# hmmscan :: search sequence(s) against a profile database # HMMER 3.4 (Aug 2023); http://hmmer.org/ # Copyright (C) 2023 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query sequence file: ../data/protein/Apulchra-genome.pep.faa # target HMM database: ../data/Pfam-A.hmm # per-dom hits tabular output: ../output/25-hmmer/Apul_hmmscan_results.domtblout # multithread parallelization: 42 workers # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: FUN_000001-T1 [L=751] Description: FUN_000001 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (751 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 918 (0.0359366); expected 510.9 (0.02) Passed bias filter: 658 (0.0257585); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.39u 1.28s 00:00:01.67 Elapsed: 00:00:06.01 # Mc/sec: 509.02 // Query: FUN_000002-T1 [L=794] Description: FUN_000002 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-07 30.7 0.1 0.025 15.5 0.0 3.0 3 SET SET domain ------ inclusion threshold ------ 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 PRDM2_PR PR domain zinc finger protein 2, PR domain 0.13 13.0 0.1 7.6 7.3 0.0 2.6 2 DUF5371 Family of unknown function (DUF5371) Domain annotation for each model (and alignments): >> SET SET domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 1.2 1e+04 10 47 .. 235 310 .. 229 346 .. 0.43 2 ! 12.4 0.0 2.6e-05 0.23 1 31 [. 684 712 .. 684 717 .. 0.81 3 ! 15.5 0.0 3e-06 0.025 65 104 .. 719 752 .. 707 753 .. 0.77 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.2 xxxxxxxxxxx..xxxxxxxxxxxxxxxx...........xxxxxxxxxx................................x RF SET 10 ikkgelileyv..ekllitkeeadkreee...........eylftldeke................................a 47 ++ ge++ + e+ ++e+++r++ + + e + FUN_000002-T1 235 FSIGEFMS-TCikEHGSTLPDEDHQRRRGrprvsslldtlD------SIEslgasssclqdqvlifqaisnfpllkyvnepmT 310 55666663.33354334444444444433466663333331......222333333333333333333333333333333333 PP == domain 2 score: 12.4 bits; conditional E-value: 2.6e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 1 GrGlfAtedikkgelileyvekllitkeead 31 G Glf+ ++i++g+l++ y++ t +ea+ FUN_000002-T1 684 GLGLFTLKKIPRGTLVCAYAP--TATIWEAR 712 89******************8..55555554 PP == domain 3 score: 15.5 bits; conditional E-value: 3e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 65 iNHscepncevevevvngekrivvfalrdIkkgeEltidY 104 i H + nc ++++ ++ i++++ rd+++geEl+++Y FUN_000002-T1 719 ISH--RVNC-EYCK---CGDGIWLKTVRDVSAGEELLMCY 752 445..4588.4444...59********************* PP >> PRDM2_PR PR domain zinc finger protein 2, PR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.6e-05 0.14 84 115 .. 724 755 .. 718 762 .. 0.89 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.6e-05 PRDM2_PR 84 NLvavqhkgeiYyrtikdIepgeeLlvwysee 115 N +++++ i+ +t++d+++geeLl++ys++ FUN_000002-T1 724 NCEYCKCGDGIWLKTVRDVSAGEELLMCYSQD 755 78889************************987 PP >> DUF5371 Family of unknown function (DUF5371) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.025 2.1e+02 6 31 .. 602 627 .. 600 636 .. 0.88 2 ? 7.3 0.0 0.00089 7.6 33 58 .. 716 741 .. 710 744 .. 0.86 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.025 DUF5371 6 HAqtvLpeedLeeLkkkcgesstkdA 31 H Lp ++ + Lk+ c + +t+ A FUN_000002-T1 602 HSNAFLPWHERQMLKQLCSQETTRTA 627 88899******************987 PP == domain 2 score: 7.3 bits; conditional E-value: 0.00089 DUF5371 33 siAveHYLeCeYtdlgedmwtkklEe 58 s + H ++CeY + g+ w k + FUN_000002-T1 716 SNVISHRVNCEYCKCGDGIWLKTVRD 741 77899***************998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (794 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 854 (0.0334312); expected 510.9 (0.02) Passed bias filter: 733 (0.0286945); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.55u 2.97s 00:00:03.52 Elapsed: 00:00:01.04 # Mc/sec: 3098.85 // Query: FUN_000003-T1 [L=57] Description: FUN_000003 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (57 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 464 (0.018164); expected 510.9 (0.02) Passed bias filter: 308 (0.0120572); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.53 # Mc/sec: 432.37 // Query: FUN_000004-T1 [L=770] Description: FUN_000004 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (770 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 946 (0.0370327); expected 510.9 (0.02) Passed bias filter: 683 (0.0267371); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.41u 0.42s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 7159.79 // Query: FUN_000005-T1 [L=794] Description: FUN_000005 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-07 30.7 0.1 0.025 15.5 0.0 3.0 3 SET SET domain ------ inclusion threshold ------ 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 PRDM2_PR PR domain zinc finger protein 2, PR domain 0.13 13.0 0.1 7.6 7.3 0.0 2.6 2 DUF5371 Family of unknown function (DUF5371) Domain annotation for each model (and alignments): >> SET SET domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 1.2 1e+04 10 47 .. 235 310 .. 229 346 .. 0.43 2 ! 12.4 0.0 2.6e-05 0.23 1 31 [. 684 712 .. 684 717 .. 0.81 3 ! 15.5 0.0 3e-06 0.025 65 104 .. 719 752 .. 707 753 .. 0.77 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.2 xxxxxxxxxxx..xxxxxxxxxxxxxxxx...........xxxxxxxxxx................................x RF SET 10 ikkgelileyv..ekllitkeeadkreee...........eylftldeke................................a 47 ++ ge++ + e+ ++e+++r++ + + e + FUN_000005-T1 235 FSIGEFMS-TCikEHGSTLPDEDHQRRRGrprvsslldtlD------SIEslgasssclqdqvlifqaisnfpllkyvnepmT 310 55666663.33354334444444444433466663333331......222333333333333333333333333333333333 PP == domain 2 score: 12.4 bits; conditional E-value: 2.6e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 1 GrGlfAtedikkgelileyvekllitkeead 31 G Glf+ ++i++g+l++ y++ t +ea+ FUN_000005-T1 684 GLGLFTLKKIPRGTLVCAYAP--TATIWEAR 712 89******************8..55555554 PP == domain 3 score: 15.5 bits; conditional E-value: 3e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 65 iNHscepncevevevvngekrivvfalrdIkkgeEltidY 104 i H + nc ++++ ++ i++++ rd+++geEl+++Y FUN_000005-T1 719 ISH--RVNC-EYCK---CGDGIWLKTVRDVSAGEELLMCY 752 445..4588.4444...59********************* PP >> PRDM2_PR PR domain zinc finger protein 2, PR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.6e-05 0.14 84 115 .. 724 755 .. 718 762 .. 0.89 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.6e-05 PRDM2_PR 84 NLvavqhkgeiYyrtikdIepgeeLlvwysee 115 N +++++ i+ +t++d+++geeLl++ys++ FUN_000005-T1 724 NCEYCKCGDGIWLKTVRDVSAGEELLMCYSQD 755 78889************************987 PP >> DUF5371 Family of unknown function (DUF5371) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.025 2.1e+02 6 31 .. 602 627 .. 600 636 .. 0.88 2 ? 7.3 0.0 0.00089 7.6 33 58 .. 716 741 .. 710 744 .. 0.86 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.025 DUF5371 6 HAqtvLpeedLeeLkkkcgesstkdA 31 H Lp ++ + Lk+ c + +t+ A FUN_000005-T1 602 HSNAFLPWHERQMLKQLCSQETTRTA 627 88899******************987 PP == domain 2 score: 7.3 bits; conditional E-value: 0.00089 DUF5371 33 siAveHYLeCeYtdlgedmwtkklEe 58 s + H ++CeY + g+ w k + FUN_000005-T1 716 SNVISHRVNCEYCKCGDGIWLKTVRD 741 77899***************998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (794 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 854 (0.0334312); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.38s 00:00:00.79 Elapsed: 00:00:00.41 # Mc/sec: 7719.59 // Query: FUN_000006-T1 [L=873] Description: FUN_000006 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (873 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 747 (0.0292425); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 8304.00 // Query: FUN_000007-T1 [L=152] Description: FUN_000007 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (152 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 501 (0.0196124); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.42s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1507.94 // Query: FUN_000008-T1 [L=99] Description: FUN_000008 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.019 15.9 0.0 0.037 15.0 0.0 1.5 2 SET SET domain Domain annotation for each model (and alignments): >> SET SET domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.28 7.3e+03 49 54 .. 32 37 .. 5 59 .. 0.59 2 ? 15.0 0.0 1.4e-06 0.037 1 23 [. 71 93 .. 71 99 .] 0.86 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.28 xxxxxx RF SET 49 yvidar 54 ++id + FUN_000008-T1 32 MYIDIQ 37 334433 PP == domain 2 score: 15.0 bits; conditional E-value: 1.4e-06 xxxxxxxxxxxxxxxxxxxxxxx RF SET 1 GrGlfAtedikkgelileyvekl 23 G Glf+ ++i++g+l++ y++++ FUN_000008-T1 71 GLGLFTLKKIPRGTLVCAYAPTA 93 89*****************9754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 567 (0.0221961); expected 510.9 (0.02) Passed bias filter: 518 (0.0202779); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.58s 00:00:00.88 Elapsed: 00:00:00.44 # Mc/sec: 908.82 // Query: FUN_000009-T1 [L=477] Description: FUN_000009 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (477 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1248 (0.048855); expected 510.9 (0.02) Passed bias filter: 676 (0.0264631); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4620.53 // Query: FUN_000010-T1 [L=241] Description: FUN_000010 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000010-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000010-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000010-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2384.47 // Query: FUN_000011-T1 [L=241] Description: FUN_000011 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000011-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000011-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000011-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2398.46 // Query: FUN_000012-T1 [L=241] Description: FUN_000012 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000012-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000012-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000012-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2432.94 // Query: FUN_000013-T1 [L=179] Description: FUN_000013 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 534 (0.0209043); expected 510.9 (0.02) Passed bias filter: 361 (0.0141319); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1763.80 // Query: FUN_000014-T1 [L=241] Description: FUN_000014 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000014-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000014-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000014-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2447.41 // Query: FUN_000015-T1 [L=241] Description: FUN_000015 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.041 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000015-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000015-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000015-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 631 (0.0247015); expected 510.9 (0.02) Passed bias filter: 520 (0.0203562); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2390.95 // Query: FUN_000016-T1 [L=241] Description: FUN_000016 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000016-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000016-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000016-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 2485.88 // Query: FUN_000017-T1 [L=241] Description: FUN_000017 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000017-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000017-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000017-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 2338.85 // Query: FUN_000018-T1 [L=241] Description: FUN_000018 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000018-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000018-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000018-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2364.92 // Query: FUN_000019-T1 [L=196] Description: FUN_000019 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (196 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 553 (0.0216481); expected 510.9 (0.02) Passed bias filter: 452 (0.0176943); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.54 # Mc/sec: 1480.56 // Query: FUN_000020-T1 [L=241] Description: FUN_000020 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000020-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000020-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000020-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.46 # Mc/sec: 2119.02 // Query: FUN_000021-T1 [L=241] Description: FUN_000021 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000021-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000021-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000021-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2409.60 // Query: FUN_000022-T1 [L=241] Description: FUN_000022 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.041 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000022-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000022-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000022-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 651 (0.0254844); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2410.69 // Query: FUN_000023-T1 [L=241] Description: FUN_000023 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000023-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000023-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000023-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2368.74 // Query: FUN_000024-T1 [L=241] Description: FUN_000024 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000024-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000024-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000024-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2378.70 // Query: FUN_000025-T1 [L=241] Description: FUN_000025 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000025-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000025-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000025-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2427.08 // Query: FUN_000026-T1 [L=241] Description: FUN_000026 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000026-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000026-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000026-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2393.75 // Query: FUN_000027-T1 [L=241] Description: FUN_000027 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000027-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000027-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000027-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2395.98 // Query: FUN_000028-T1 [L=196] Description: FUN_000028 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (196 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 553 (0.0216481); expected 510.9 (0.02) Passed bias filter: 452 (0.0176943); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1911.23 // Query: FUN_000029-T1 [L=280] Description: FUN_000029 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-07 31.0 5.8 0.00016 22.1 0.6 2.5 2 zf-CCHC Zinc knuckle 0.0015 18.7 0.6 0.0015 18.7 0.6 2.8 3 zf-CCHC_5 GAG-polyprotein viral zinc-finger 0.0024 18.2 0.0 0.0049 17.2 0.0 1.5 1 RRM_1 RNA recognition motif ------ inclusion threshold ------ 0.12 11.9 0.5 0.2 11.2 0.5 1.3 1 DUF4663 Domain of unknown function (DUF4663) 0.26 11.8 0.0 0.52 10.8 0.0 1.5 1 RRM_7 RNA recognition motif 0.3 11.4 6.7 3.9 7.8 1.0 2.4 2 zf-CCHC_2 Zinc knuckle 1.4 9.1 5.0 16 5.7 0.6 2.9 3 zf-CCHC_4 Zinc knuckle Domain annotation for each model (and alignments): >> zf-CCHC Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.5 0.00011 0.41 3 17 .. 154 168 .. 152 168 .. 0.91 2 ! 22.1 0.6 4.4e-08 0.00016 3 18 .] 173 188 .. 171 188 .. 0.91 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00011 zf-CCHC 3 CynCGepGHiardCp 17 C C e GH+ rdC FUN_000029-T1 154 CSVCRESGHLPRDCR 168 999***********5 PP == domain 2 score: 22.1 bits; conditional E-value: 4.4e-08 zf-CCHC 3 CynCGepGHiardCpk 18 C +C +pGH+ar+Cp+ FUN_000029-T1 173 CLKCRQPGHVARNCPS 188 889************6 PP >> zf-CCHC_5 GAG-polyprotein viral zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 1.1 0.15 5.3e+02 4 19 .. 153 168 .. 150 168 .. 0.87 2 ! 18.7 0.6 4e-07 0.0015 2 20 .. 170 188 .. 169 191 .. 0.92 3 ? -2.0 0.1 1.2 4.2e+03 15 21 .. 213 219 .. 212 221 .. 0.87 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.15 zf-CCHC_5 4 lCpRCkkgkHwardCh 19 C C H rdC+ FUN_000029-T1 153 FCSVCRESGHLPRDCR 168 68999999*******7 PP == domain 2 score: 18.7 bits; conditional E-value: 4e-07 zf-CCHC_5 2 pglCpRCkkgkHwardChs 20 +glC++C + H+ar+C s FUN_000029-T1 170 SGLCLKCRQPGHVARNCPS 188 79***************88 PP == domain 3 score: -2.0 bits; conditional E-value: 1.2 zf-CCHC_5 15 ardChsk 21 ar C s+ FUN_000029-T1 213 ARHCTSR 219 899**98 PP >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 1.3e-06 0.0049 1 30 [. 79 108 .. 79 116 .. 0.94 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.3e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirl 30 ++V++Lp++v++ ++ F+ fG + sir FUN_000029-T1 79 VYVRDLPFEVSDADVVSAFRSFGVVLSIRP 108 8**************************986 PP >> DUF4663 Domain of unknown function (DUF4663) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.5 5.4e-05 0.2 279 312 .. 189 222 .. 162 230 .. 0.89 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 5.4e-05 DUF4663 279 snslldsdplPlaqsnPtPpsqgapegrtsrfsy 312 s sll sdp+P+ s+ +Pps a tsr++ FUN_000029-T1 189 STSLLSSDPTPVPASPESPPSVMAARHCTSRLTD 222 7899**************************9875 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00014 0.52 4 29 .. 79 104 .. 77 116 .. 0.92 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00014 RRM_7 4 vfvGGlPiDiteeeltatfkafGkll 29 v+v lP+++++++++++f++fG +l FUN_000029-T1 79 VYVRDLPFEVSDADVVSAFRSFGVVL 104 89999******************985 PP >> zf-CCHC_2 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.5 0.0031 11 6 20 .. 154 168 .. 153 168 .. 0.92 2 ? 7.8 1.0 0.0011 3.9 6 20 .. 173 187 .. 172 188 .. 0.89 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0031 zf-CCHC_2 6 ChiCgkkGHyIqdCP 20 C +C + GH+ +dC+ FUN_000029-T1 154 CSVCRESGHLPRDCR 168 889***********5 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0011 zf-CCHC_2 6 ChiCgkkGHyIqdCP 20 C C ++GH ++CP FUN_000029-T1 173 CLKCRQPGHVARNCP 187 888***********9 PP >> zf-CCHC_4 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 1.5 5.5e+03 2 13 .. 127 138 .. 126 140 .. 0.79 2 ? 5.7 0.6 0.0045 16 33 49 .] 153 169 .. 151 169 .. 0.93 3 ? 4.9 0.3 0.0078 28 31 48 .. 170 187 .. 168 188 .. 0.89 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1.5 zf-CCHC_4 2 dvtkPLrffrri 13 +t+PL ++ ++ FUN_000029-T1 127 SFTDPLPSSLHV 138 69****888776 PP == domain 2 score: 5.7 bits; conditional E-value: 0.0045 zf-CCHC_4 33 fCfiCgrlgHsdkfCpk 49 fC++C gH ++C++ FUN_000029-T1 153 FCSVCRESGHLPRDCRY 169 9**************86 PP == domain 3 score: 4.9 bits; conditional E-value: 0.0078 zf-CCHC_4 31 rrfCfiCgrlgHsdkfCp 48 + +C C gH ++Cp FUN_000029-T1 170 SGLCLKCRQPGHVARNCP 187 689**************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (280 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 542 (0.0212175); expected 510.9 (0.02) Passed bias filter: 416 (0.016285); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2772.48 // Query: FUN_000030-T1 [L=241] Description: FUN_000030 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.2 0.0 0.083 13.3 0.0 1.5 1 RRM_1 RNA recognition motif 0.12 12.7 1.6 0.25 11.6 1.6 1.5 1 zf-C2H2_10 C2H2 zinc-finger 0.22 12.0 0.0 0.44 11.0 0.0 1.5 1 RRM_7 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 9.7e-06 0.083 1 28 [. 86 113 .. 86 117 .. 0.94 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 9.7e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksi 28 +fV++Lp +++++++k F+ fG + s+ FUN_000030-T1 86 VFVRDLPVELSDDDVKCAFESFGVVHSV 113 8***********************9876 PP >> zf-C2H2_10 C2H2 zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.6 3e-05 0.25 4 15 .. 159 170 .. 158 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3e-05 zf-C2H2_10 4 itCSYChetGHt 15 ++CS Che GH FUN_000030-T1 159 VQCSICHEFGHQ 170 68*********5 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 5.2e-05 0.44 3 28 .. 85 110 .. 83 115 .. 0.92 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.2e-05 RRM_7 3 kvfvGGlPiDiteeeltatfkafGkl 28 vfv lP+++++++++ +f++fG + FUN_000030-T1 85 PVFVRDLPVELSDDDVKCAFESFGVV 110 69**********************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 637 (0.0249364); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2433.82 // Query: FUN_000031-T1 [L=92] Description: FUN_000031 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (92 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 500 (0.0195733); expected 510.9 (0.02) Passed bias filter: 213 (0.00833823); expected 510.9 (0.02) Passed Vit filter: 10 (0.000391466); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 928.60 // Query: FUN_000032-T1 [L=815] Description: FUN_000032 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.39 11.2 2.6 99 3.6 0.1 3.4 3 Zn_ribbon_8 Zinc ribbon domain Domain annotation for each model (and alignments): >> Zn_ribbon_8 Zinc ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 0.0039 99 18 35 .. 65 82 .. 63 85 .. 0.81 2 ? 1.8 0.1 0.014 3.5e+02 18 35 .. 94 111 .. 91 114 .. 0.80 3 ? 3.5 0.1 0.004 1e+02 18 35 .. 123 140 .. 120 143 .. 0.81 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.0039 Zn_ribbon_8 18 lqkmsdapltaCPeCgsg 35 +++ +++plt+CP+ ++ FUN_000032-T1 65 FHRKHEPPLTPCPRTSQE 82 677889*******99774 PP == domain 2 score: 1.8 bits; conditional E-value: 0.014 Zn_ribbon_8 18 lqkmsdapltaCPeCgsg 35 +++ +++pl +CP+ ++ FUN_000032-T1 94 FHRKHEPPLIPCPRTSQE 111 67778999999**99774 PP == domain 3 score: 3.5 bits; conditional E-value: 0.004 Zn_ribbon_8 18 lqkmsdapltaCPeCgsg 35 +++ +++plt+CP+ ++ FUN_000032-T1 123 FHRKHEPPLTPCPRTSQE 140 677889*******99774 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (815 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 998 (0.0390683); expected 510.9 (0.02) Passed bias filter: 729 (0.0285379); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.40u 0.41s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7663.34 // Query: FUN_000033-T1 [L=779] Description: FUN_000033 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-07 30.7 0.1 0.025 15.5 0.0 3.0 3 SET SET domain ------ inclusion threshold ------ 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 PRDM2_PR PR domain zinc finger protein 2, PR domain 0.12 13.1 0.1 7.4 7.3 0.0 2.6 2 DUF5371 Family of unknown function (DUF5371) Domain annotation for each model (and alignments): >> SET SET domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 1.1 9.7e+03 10 47 .. 220 295 .. 214 331 .. 0.43 2 ! 12.5 0.0 2.6e-05 0.22 1 31 [. 669 697 .. 669 702 .. 0.81 3 ! 15.5 0.0 2.9e-06 0.025 65 104 .. 704 737 .. 692 738 .. 0.77 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.1 xxxxxxxxxxx..xxxxxxxxxxxxxxxx...........xxxxxxxxxx................................x RF SET 10 ikkgelileyv..ekllitkeeadkreee...........eylftldeke................................a 47 ++ ge++ + e+ ++e+++r++ + + e + FUN_000033-T1 220 FSIGEFMS-TCikEHGSTLPDEDHQRRRGrprvsslldtlD------SIEslgasssclqdqvlifqaisnfpllkyvnepmT 295 55666663.33354334444444444433466663333331......222333333333333333333333333333333333 PP == domain 2 score: 12.5 bits; conditional E-value: 2.6e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 1 GrGlfAtedikkgelileyvekllitkeead 31 G Glf+ ++i++g+l++ y++ t +ea+ FUN_000033-T1 669 GLGLFTLKKIPRGTLVCAYAP--TATIWEAR 697 89******************8..55555554 PP == domain 3 score: 15.5 bits; conditional E-value: 2.9e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 65 iNHscepncevevevvngekrivvfalrdIkkgeEltidY 104 i H + nc ++++ ++ i++++ rd+++geEl+++Y FUN_000033-T1 704 ISH--RVNC-EYCK---CGDGIWLKTVRDVSAGEELLMCY 737 445..4588.4444...59********************* PP >> PRDM2_PR PR domain zinc finger protein 2, PR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.6e-05 0.14 84 115 .. 709 740 .. 703 747 .. 0.89 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.6e-05 PRDM2_PR 84 NLvavqhkgeiYyrtikdIepgeeLlvwysee 115 N +++++ i+ +t++d+++geeLl++ys++ FUN_000033-T1 709 NCEYCKCGDGIWLKTVRDVSAGEELLMCYSQD 740 78889************************987 PP >> DUF5371 Family of unknown function (DUF5371) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.025 2.1e+02 6 31 .. 587 612 .. 585 621 .. 0.88 2 ? 7.3 0.0 0.00087 7.4 33 58 .. 701 726 .. 695 729 .. 0.86 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.025 DUF5371 6 HAqtvLpeedLeeLkkkcgesstkdA 31 H Lp ++ + Lk+ c + +t+ A FUN_000033-T1 587 HSNAFLPWHERQMLKQLCSQETTRTA 612 88899******************987 PP == domain 2 score: 7.3 bits; conditional E-value: 0.00087 DUF5371 33 siAveHYLeCeYtdlgedmwtkklEe 58 s + H ++CeY + g+ w k + FUN_000033-T1 701 SNVISHRVNCEYCKCGDGIWLKTVRD 726 77899***************998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (779 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 785 (0.0307301); expected 510.9 (0.02) Passed bias filter: 697 (0.0272852); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.41s 00:00:00.82 Elapsed: 00:00:00.44 # Mc/sec: 7208.27 // Query: FUN_000034-T1 [L=507] Description: FUN_000034 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_000034-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_000034-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_000034-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_000034-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 4982.86 // Query: FUN_000035-T1 [L=702] Description: FUN_000035 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.12 13.3 0.0 1.4 9.9 0.0 2.4 2 DUF1214 Protein of unknown function (DUF1214) 0.54 10.4 7.2 0.055 13.6 1.9 2.0 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter 0.68 10.7 3.1 1.2 10.0 0.1 2.9 2 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 3.5e-09 2.2e-05 56 142 .. 443 537 .. 432 568 .. 0.84 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.5e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_000035-T1 443 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 535 455444445555679*****9999********9999999999******************************995555.6************96 PP Phage_integrase 141 le 142 + FUN_000035-T1 536 YS 537 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.22 1.4e+03 48 88 .. 113 153 .. 103 157 .. 0.74 2 ? 9.9 0.0 0.00022 1.4 57 108 .. 425 474 .. 406 477 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.22 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_000035-T1 113 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 153 556777778666666767889999**********9985544 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00022 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_000035-T1 425 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 474 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 1.9 8.6e-06 0.055 83 123 .. 72 112 .. 24 123 .. 0.79 2 ? -3.5 0.0 1.6 1e+04 24 42 .. 547 565 .. 534 594 .. 0.52 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8.6e-06 MVD-like_N 83 kvkveSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_000035-T1 72 AGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 5556899999********************99988766554 PP == domain 2 score: -3.5 bits; conditional E-value: 1.6 MVD-like_N 24 sSlSltldelytkttvefs 42 +Sl +l++ + + + +++ FUN_000035-T1 547 DSLAAALRHSREQAQSTYD 565 3444444433322222222 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.1 0.00019 1.2 1 32 [. 280 311 .. 280 343 .. 0.87 2 ? -0.8 0.5 0.44 2.8e+03 29 69 .. 531 568 .. 520 578 .. 0.71 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_000035-T1 280 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 311 689*******************9998665555 PP == domain 2 score: -0.8 bits; conditional E-value: 0.44 Phage_int_SAM_1 29 flkflseegesleqittsdvraflaelkaeglsasslarrl 69 fl+++ + ++ +++ ++++a l++++++ ++s+ rr FUN_000035-T1 531 FLTWAYS-QSECTDSMKDSLAAALRHSREQ--AQSTYDRRT 568 4444444.7788888888889999998884..567766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (702 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6899.22 // Query: FUN_000036-T1 [L=697] Description: FUN_000036 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.59 11.3 1.8 1.7 9.9 1.8 1.8 1 DUF4404 Domain of unknown function (DUF4404) 1.3 9.5 4.9 0.69 10.4 2.0 1.9 2 VWC2L_1st VWC2L-like, N-terminal domain Domain annotation for each model (and alignments): >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 1.8 0.00013 1.7 4 60 .. 429 486 .. 427 490 .. 0.89 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00013 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_000036-T1 429 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 486 799****************99988776167**************99********9998 PP >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 0.33 4.2e+03 20 27 .. 490 497 .. 484 501 .. 0.69 2 ? 10.4 2.0 5.4e-05 0.69 22 33 .. 511 523 .. 508 532 .. 0.86 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.33 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_000036-T1 490 SQAECTCL 497 55667775 PP == domain 2 score: 10.4 bits; conditional E-value: 5.4e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_000036-T1 511 QNCPyCICTEEGG 523 79*********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (697 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1551 (0.0607164); expected 510.9 (0.02) Passed bias filter: 644 (0.0252104); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 6730.03 // Query: FUN_000037-T1 [L=603] Description: FUN_000037 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.55 11.0 3.3 1.1 10.0 0.0 3.1 3 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 0.14 3.5e+03 53 70 .. 18 35 .. 10 36 .. 0.71 2 ? -2.4 0.1 0.33 8.3e+03 38 70 .. 105 139 .. 99 142 .. 0.67 3 ? 10.0 0.0 4.4e-05 1.1 1 30 [. 255 284 .. 255 299 .. 0.85 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.14 Phage_int_SAM_1 53 aelkaeglsasslarrlS 70 ++++g +a++++r+ S FUN_000037-T1 18 LNRQQRGIKATTANRTAS 35 45666799******9866 PP == domain 2 score: -2.4 bits; conditional E-value: 0.33 Phage_int_SAM_1 38 esleqittsdvraflaelkaeg..lsasslarrlS 70 +s++q+++ + +++ ++++ s++s + rlS FUN_000037-T1 105 KSWQQVQRLVPSIYVSPSSESEdqDSEASRRSRLS 139 67888888777778777776654456666666666 PP == domain 3 score: 10.0 bits; conditional E-value: 4.4e-05 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkafl 30 +e++l++L+ rglS T+ ++++ L l FUN_000037-T1 255 LESYLDHLKDHRGLSSATIANHASSLVYPL 284 689*******************99986555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (603 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 732 (0.0286553); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5773.62 // Query: FUN_000038-T1 [L=252] Description: FUN_000038 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.8 4.4 0.21 12.0 2.0 2.3 2 VWC2L_1st VWC2L-like, N-terminal domain Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.047 1.2e+03 20 27 .. 45 52 .. 38 56 .. 0.69 2 ? 12.0 2.0 8.2e-06 0.21 22 33 .. 66 78 .. 63 87 .. 0.86 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.047 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_000038-T1 45 SQAECTCL 52 55677775 PP == domain 2 score: 12.0 bits; conditional E-value: 8.2e-06 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_000038-T1 66 QNCPyCICTEEGG 78 79*********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (252 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1825 (0.0714426); expected 510.9 (0.02) Passed bias filter: 943 (0.0369152); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 2517.56 // Query: FUN_000039-T1 [L=247] Description: FUN_000039 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 5.5 6.6 4.0 7.3 6.2 4.0 1.1 1 TrbL_3 TrbL/VirB6 plasmid conjugal transfer like protein Domain annotation for each model (and alignments): >> TrbL_3 TrbL/VirB6 plasmid conjugal transfer like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 4.0 0.00029 7.3 265 321 .. 126 181 .. 102 206 .. 0.66 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.00029 TrbL_3 265 llalvspltwkafaayatpaaaaasggaarrrsekggevggaavsgarnvtrgards 321 ++ +++t +++++ a+ a+a +s+g +rrr++k+ ++ aa+++a ++t+++ FUN_000039-T1 126 YVSTRQMVT-QQLQVRAATARASGSSGMTRRRKQKAPRRKPAASQRAPEATATSTAT 181 566666777.89989999999999999997777777777777766666444444422 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (247 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1396 (0.0546487); expected 510.9 (0.02) Passed bias filter: 674 (0.0263848); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2497.01 // Query: FUN_000040-T1 [L=702] Description: FUN_000040 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.12 13.3 0.0 1.4 9.9 0.0 2.4 2 DUF1214 Protein of unknown function (DUF1214) 0.54 10.4 7.2 0.055 13.6 1.9 2.0 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter 0.68 10.7 3.1 1.2 10.0 0.1 2.9 2 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 3.5e-09 2.2e-05 56 142 .. 443 537 .. 432 568 .. 0.84 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.5e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_000040-T1 443 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 535 455444445555679*****9999********9999999999******************************995555.6************96 PP Phage_integrase 141 le 142 + FUN_000040-T1 536 YS 537 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.22 1.4e+03 48 88 .. 113 153 .. 103 157 .. 0.74 2 ? 9.9 0.0 0.00022 1.4 57 108 .. 425 474 .. 406 477 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.22 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_000040-T1 113 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 153 556777778666666767889999**********9985544 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00022 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_000040-T1 425 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 474 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 1.9 8.6e-06 0.055 83 123 .. 72 112 .. 24 123 .. 0.79 2 ? -3.5 0.0 1.6 1e+04 24 42 .. 547 565 .. 534 594 .. 0.52 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8.6e-06 MVD-like_N 83 kvkveSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_000040-T1 72 AGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 5556899999********************99988766554 PP == domain 2 score: -3.5 bits; conditional E-value: 1.6 MVD-like_N 24 sSlSltldelytkttvefs 42 +Sl +l++ + + + +++ FUN_000040-T1 547 DSLAAALRHSREQAQSTYD 565 3444444433322222222 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.1 0.00019 1.2 1 32 [. 280 311 .. 280 343 .. 0.87 2 ? -0.8 0.5 0.44 2.8e+03 29 69 .. 531 568 .. 520 578 .. 0.71 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_000040-T1 280 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 311 689*******************9998665555 PP == domain 2 score: -0.8 bits; conditional E-value: 0.44 Phage_int_SAM_1 29 flkflseegesleqittsdvraflaelkaeglsasslarrl 69 fl+++ + ++ +++ ++++a l++++++ ++s+ rr FUN_000040-T1 531 FLTWAYS-QSECTDSMKDSLAAALRHSREQ--AQSTYDRRT 568 4444444.7788888888889999998884..567766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (702 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.43 # Mc/sec: 6609.97 // Query: FUN_000041-T1 [L=507] Description: FUN_000041 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_000041-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_000041-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_000041-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_000041-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 4788.01 // Query: FUN_000042-T1 [L=264] Description: FUN_000042 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.012 15.7 2.0 0.012 15.7 2.0 1.9 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal Domain annotation for each model (and alignments): >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 2.0 4.8e-07 0.012 81 123 .. 70 112 .. 22 123 .. 0.77 2 ? -1.7 0.6 0.11 2.8e+03 99 113 .. 133 147 .. 124 172 .. 0.51 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 4.8e-07 MVD-like_N 81 elkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 + +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_000042-T1 70 DDAGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 555567899999********************99988766554 PP == domain 2 score: -1.7 bits; conditional E-value: 0.11 MVD-like_N 99 ASSasgfAalalala 113 A S ++ A++ ++ + FUN_000042-T1 133 AASTAASASIYVSPS 147 344444444443333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (264 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 796 (0.0311607); expected 510.9 (0.02) Passed bias filter: 488 (0.0191035); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2651.90 // Query: FUN_000043-T1 [L=347] Description: FUN_000043 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-06 27.6 0.0 6.2e-06 26.6 0.0 1.5 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.22 12.5 0.0 0.5 11.3 0.0 1.6 1 DUF1214 Protein of unknown function (DUF1214) Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.0 4.9e-10 6.2e-06 56 142 .. 88 182 .. 76 214 .. 0.83 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 4.9e-10 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_000043-T1 88 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 180 455444445555679*****9999********9999999999******************************995555.6************97 PP Phage_integrase 141 le 142 + FUN_000043-T1 181 YS 182 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 3.9e-05 0.5 57 108 .. 70 119 .. 39 122 .. 0.86 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 3.9e-05 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_000043-T1 70 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 119 55666664..5789**************999**********99999999988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (347 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 792 (0.0310041); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3372.45 // Query: FUN_000044-T1 [L=507] Description: FUN_000044 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_000044-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_000044-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_000044-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_000044-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.40u 0.36s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4829.01 // Query: FUN_000045-T1 [L=359] Description: FUN_000045 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.019 15.1 1.9 0.019 15.1 1.9 1.8 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter 0.16 12.8 0.0 0.5 11.2 0.0 1.9 1 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 1.9 1.5e-06 0.019 81 123 .. 70 112 .. 22 123 .. 0.77 2 ? -1.7 0.2 0.23 2.9e+03 95 111 .. 133 145 .. 117 171 .. 0.56 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.5e-06 MVD-like_N 81 elkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 + +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_000045-T1 70 DDAGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 555567899999********************99988766554 PP == domain 2 score: -1.7 bits; conditional E-value: 0.23 MVD-like_N 95 aaglASSasgfAalala 111 aa A Sa ++ ++ FUN_000045-T1 133 AASTAASA----SIYVS 145 33333333....33333 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 3.9e-05 0.5 1 32 [. 280 311 .. 280 340 .. 0.86 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 3.9e-05 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_000045-T1 280 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 311 689*******************9998665555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (359 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 583 (0.0228225); expected 510.9 (0.02) Passed bias filter: 396 (0.0155021); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3577.98 // Query: FUN_000046-T1 [L=126] Description: FUN_000046 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.2e-15 58.1 0.0 1.6e-15 57.7 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 1.9e-05 25.3 0.0 2.7e-05 24.8 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.3e-05 24.5 0.0 3.9e-05 23.8 0.0 1.4 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2e-24 1.3e-20 1 34 [. 92 125 .. 92 126 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000046-T1 92 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 125 9*******************************97 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.7 0.0 2.6e-19 1.6e-15 8 87 .. 11 89 .. 6 90 .. 0.94 Alignments for each domain: == domain 1 score: 57.7 bits; conditional E-value: 2.6e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000046-T1 11 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 89 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 4.3e-09 2.7e-05 2 65 .] 25 88 .. 24 88 .. 0.98 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 4.3e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000046-T1 25 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 88 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 6.2e-09 3.9e-05 94 136 .] 12 54 .. 4 54 .. 0.89 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 6.2e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000046-T1 12 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 54 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 506 (0.0198082); expected 510.9 (0.02) Passed bias filter: 424 (0.0165982); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1287.53 // Query: FUN_000047-T1 [L=139] Description: FUN_000047 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000047-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000047-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000047-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000047-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000047-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000047-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000047-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000047-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000047-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1417.17 // Query: FUN_000048-T1 [L=181] Description: FUN_000048 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-19 70.5 0.4 2.9e-19 69.7 0.4 1.4 1 Histone Core histone H2A/H2B/H3/H4 domain 2.4e-08 34.2 0.0 4.6e-08 33.3 0.0 1.5 1 Histone_ABTB Histone domain in ABTB family protein 0.0019 18.9 0.0 0.0058 17.4 0.0 1.8 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) ------ inclusion threshold ------ 0.015 15.8 0.1 0.02 15.3 0.1 1.1 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repe 0.099 13.1 0.1 0.19 12.2 0.1 1.4 1 RNase_P-MRP_p29 Ribonuclease P/MRP, subunit p29 Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.7 0.4 5.6e-23 2.9e-19 7 88 .] 79 156 .. 73 156 .. 0.94 Alignments for each domain: == domain 1 score: 69.7 bits; conditional E-value: 5.6e-23 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000048-T1 79 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 156 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.0 9e-12 4.6e-08 10 91 .. 100 180 .. 95 181 .] 0.84 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 9e-12 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000048-T1 100 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 180 5555544333...788899999999999*************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 1.1e-06 0.0058 8 65 .] 97 154 .. 96 154 .. 0.95 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 1.1e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000048-T1 97 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 154 679*****88888.*****************************************9996 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.1 3.9e-06 0.02 41 117 .. 79 157 .. 51 161 .. 0.73 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.9e-06 ARM_TT21 41 kskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000048-T1 79 AETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 157 2222333345556777889999*******************98765266656788**********************98 PP >> RNase_P-MRP_p29 Ribonuclease P/MRP, subunit p29 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 3.7e-05 0.19 25 55 .. 46 76 .. 37 95 .. 0.91 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.7e-05 RNase_P-MRP_p29 25 GikGivvdEtkntlkivtkenkvktipKegs 55 i+G++ +Et+ +lk++ ++ k++ K++s FUN_000048-T1 46 RISGLIYEETRGVLKVAAAKKGEKRVGKAKS 76 689************************9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 682 (0.026698); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1825.26 // Query: FUN_000049-T1 [L=164] Description: FUN_000049 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000049-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000049-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000049-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 1592.72 // Query: FUN_000050-T1 [L=129] Description: FUN_000050 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000050-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000050-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000050-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000050-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1294.17 // Query: FUN_000051-T1 [L=164] Description: FUN_000051 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000051-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000051-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000051-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1618.10 // Query: FUN_000052-T1 [L=129] Description: FUN_000052 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000052-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000052-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000052-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000052-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1272.81 // Query: FUN_000053-T1 [L=164] Description: FUN_000053 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000053-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000053-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000053-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1607.27 // Query: FUN_000054-T1 [L=129] Description: FUN_000054 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000054-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000054-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000054-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000054-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1311.49 // Query: FUN_000055-T1 [L=164] Description: FUN_000055 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000055-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000055-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000055-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 1582.94 // Query: FUN_000056-T1 [L=129] Description: FUN_000056 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000056-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000056-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000056-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000056-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1300.92 // Query: FUN_000057-T1 [L=164] Description: FUN_000057 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000057-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000057-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000057-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1647.89 // Query: FUN_000058-T1 [L=129] Description: FUN_000058 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000058-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000058-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000058-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000058-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.38 # Mc/sec: 1349.60 // Query: FUN_000059-T1 [L=164] Description: FUN_000059 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000059-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000059-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000059-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1640.36 // Query: FUN_000060-T1 [L=129] Description: FUN_000060 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000060-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000060-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000060-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000060-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1329.17 // Query: FUN_000061-T1 [L=164] Description: FUN_000061 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000061-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000061-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000061-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1598.74 // Query: FUN_000062-T1 [L=129] Description: FUN_000062 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000062-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000062-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000062-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000062-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1301.73 // Query: FUN_000063-T1 [L=164] Description: FUN_000063 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000063-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000063-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000063-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1615.35 // Query: FUN_000064-T1 [L=129] Description: FUN_000064 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000064-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000064-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000064-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000064-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1300.62 // Query: FUN_000065-T1 [L=139] Description: FUN_000065 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000065-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000065-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000065-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000065-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000065-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000065-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000065-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000065-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000065-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.25u 0.42s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1391.84 // Query: FUN_000066-T1 [L=181] Description: FUN_000066 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-19 70.5 0.4 2.9e-19 69.7 0.4 1.4 1 Histone Core histone H2A/H2B/H3/H4 domain 2.4e-08 34.2 0.0 4.6e-08 33.3 0.0 1.5 1 Histone_ABTB Histone domain in ABTB family protein 0.0019 18.9 0.0 0.0058 17.4 0.0 1.8 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) ------ inclusion threshold ------ 0.015 15.8 0.1 0.02 15.3 0.1 1.1 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repe 0.099 13.1 0.1 0.19 12.2 0.1 1.4 1 RNase_P-MRP_p29 Ribonuclease P/MRP, subunit p29 Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.7 0.4 5.6e-23 2.9e-19 7 88 .] 79 156 .. 73 156 .. 0.94 Alignments for each domain: == domain 1 score: 69.7 bits; conditional E-value: 5.6e-23 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000066-T1 79 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 156 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.0 9e-12 4.6e-08 10 91 .. 100 180 .. 95 181 .] 0.84 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 9e-12 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000066-T1 100 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 180 5555544333...788899999999999*************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 1.1e-06 0.0058 8 65 .] 97 154 .. 96 154 .. 0.95 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 1.1e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000066-T1 97 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 154 679*****88888.*****************************************9996 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.1 3.9e-06 0.02 41 117 .. 79 157 .. 51 161 .. 0.73 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.9e-06 ARM_TT21 41 kskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000066-T1 79 AETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 157 2222333345556777889999*******************98765266656788**********************98 PP >> RNase_P-MRP_p29 Ribonuclease P/MRP, subunit p29 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 3.7e-05 0.19 25 55 .. 46 76 .. 37 95 .. 0.91 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.7e-05 RNase_P-MRP_p29 25 GikGivvdEtkntlkivtkenkvktipKegs 55 i+G++ +Et+ +lk++ ++ k++ K++s FUN_000066-T1 46 RISGLIYEETRGVLKVAAAKKGEKRVGKAKS 76 689************************9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 682 (0.026698); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1782.20 // Query: FUN_000067-T1 [L=164] Description: FUN_000067 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000067-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000067-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000067-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1615.20 // Query: FUN_000068-T1 [L=129] Description: FUN_000068 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000068-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000068-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000068-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000068-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1316.72 // Query: FUN_000069-T1 [L=238] Description: FUN_000069 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-54 181.7 0.1 4.2e-38 130.1 0.2 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 1.6e-20 73.0 1.7 3.6e-20 71.9 1.7 1.7 1 Histone_H2A_C C-terminus of histone H2A 7.8e-10 39.4 0.0 0.00011 22.9 0.0 2.4 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 6.2e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 CENP-T_C Centromere kinetochore component CENP-T his 0.00089 20.5 0.9 0.0014 19.9 0.9 1.3 1 PAF PCNA-associated factor histone like domain 0.0015 19.3 0.1 0.0045 17.9 0.0 1.7 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.033 14.7 0.1 0.28 11.7 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD s 0.065 13.6 0.0 0.14 12.6 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.1 0.2 1.3e-41 4.2e-38 1 88 [] 44 131 .. 44 131 .. 0.99 2 ! 49.5 0.0 1.8e-16 5.8e-13 21 87 .. 136 201 .. 132 202 .. 0.95 Alignments for each domain: == domain 1 score: 130.1 bits; conditional E-value: 1.3e-41 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000069-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 131 689************************************************************************************7 PP == domain 2 score: 49.5 bits; conditional E-value: 1.8e-16 Histone 21 qklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000069-T1 136 LQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 201 689**********8.89999**********************************************9 PP >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.9 1.7 1.1e-23 3.6e-20 1 34 [. 204 237 .. 204 238 .] 0.97 Alignments for each domain: == domain 1 score: 71.9 bits; conditional E-value: 1.1e-23 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000069-T1 204 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 237 9*******************************96 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 1.7e-05 0.054 2 64 .. 65 128 .. 64 128 .. 0.93 2 ! 22.9 0.0 3.4e-08 0.00011 2 65 .] 137 200 .. 136 200 .. 0.98 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.7e-05 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000069-T1 65 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 128 7888888887888889999******************************************998 PP == domain 2 score: 22.9 bits; conditional E-value: 3.4e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000069-T1 137 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 200 69************************************************************98 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.3e-08 0.00017 11 77 .. 70 130 .. 59 143 .. 0.83 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.3e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000069-T1 70 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 130 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.9 4.3e-07 0.0014 1 62 [. 1 58 [. 1 80 [. 0.90 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 4.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000069-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 58 99***998...9***************999999999988899999998.6999999999996 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-06 0.0045 14 71 .. 71 130 .. 65 134 .. 0.83 2 ? -2.0 0.0 2.1 6.7e+03 53 76 .] 183 206 .. 160 206 .. 0.71 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-06 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000069-T1 71 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 444433311666789999*************************************99876 PP == domain 2 score: -2.0 bits; conditional E-value: 2.1 CENP-S 53 AkHAkRstittdDvlLlaRrnesL 76 A+ k+s i + + L +R++e+L FUN_000069-T1 183 ARDNKKSRIIPRHLQLAVRNDEEL 206 455567777777788888887765 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 8.8e-05 0.28 23 70 .. 85 132 .. 69 148 .. 0.87 2 ? 0.3 0.0 0.31 9.8e+02 40 69 .. 173 202 .. 160 211 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.8e-05 TFIID-31kDa 23 yeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA r FUN_000069-T1 85 FQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIR 132 78889999***********************************96655 PP == domain 2 score: 0.3 bits; conditional E-value: 0.31 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000069-T1 173 AEILELAGNAARDNKKSRIIPRHLQLAVRN 202 689999999999999999999999999975 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 4.3e-05 0.14 35 77 .] 51 93 .. 49 93 .. 0.92 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.3e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000069-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66677889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2372.56 // Query: FUN_000070-T1 [L=238] Description: FUN_000070 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-54 181.7 0.1 4.2e-38 130.1 0.2 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 1.6e-20 73.0 1.7 3.6e-20 71.9 1.7 1.7 1 Histone_H2A_C C-terminus of histone H2A 7.8e-10 39.4 0.0 0.00011 22.9 0.0 2.4 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 6.2e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 CENP-T_C Centromere kinetochore component CENP-T his 0.00089 20.5 0.9 0.0014 19.9 0.9 1.3 1 PAF PCNA-associated factor histone like domain 0.0015 19.3 0.1 0.0045 17.9 0.0 1.7 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.033 14.7 0.1 0.28 11.7 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD s 0.065 13.6 0.0 0.14 12.6 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.1 0.2 1.3e-41 4.2e-38 1 88 [] 44 131 .. 44 131 .. 0.99 2 ! 49.5 0.0 1.8e-16 5.8e-13 21 87 .. 136 201 .. 132 202 .. 0.95 Alignments for each domain: == domain 1 score: 130.1 bits; conditional E-value: 1.3e-41 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000070-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 131 689************************************************************************************7 PP == domain 2 score: 49.5 bits; conditional E-value: 1.8e-16 Histone 21 qklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000070-T1 136 LQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 201 689**********8.89999**********************************************9 PP >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.9 1.7 1.1e-23 3.6e-20 1 34 [. 204 237 .. 204 238 .] 0.97 Alignments for each domain: == domain 1 score: 71.9 bits; conditional E-value: 1.1e-23 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000070-T1 204 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 237 9*******************************96 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 1.7e-05 0.054 2 64 .. 65 128 .. 64 128 .. 0.93 2 ! 22.9 0.0 3.4e-08 0.00011 2 65 .] 137 200 .. 136 200 .. 0.98 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.7e-05 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000070-T1 65 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 128 7888888887888889999******************************************998 PP == domain 2 score: 22.9 bits; conditional E-value: 3.4e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000070-T1 137 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 200 69************************************************************98 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.3e-08 0.00017 11 77 .. 70 130 .. 59 143 .. 0.83 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.3e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000070-T1 70 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 130 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.9 4.3e-07 0.0014 1 62 [. 1 58 [. 1 80 [. 0.90 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 4.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000070-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 58 99***998...9***************999999999988899999998.6999999999996 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-06 0.0045 14 71 .. 71 130 .. 65 134 .. 0.83 2 ? -2.0 0.0 2.1 6.7e+03 53 76 .] 183 206 .. 160 206 .. 0.71 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-06 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000070-T1 71 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 444433311666789999*************************************99876 PP == domain 2 score: -2.0 bits; conditional E-value: 2.1 CENP-S 53 AkHAkRstittdDvlLlaRrnesL 76 A+ k+s i + + L +R++e+L FUN_000070-T1 183 ARDNKKSRIIPRHLQLAVRNDEEL 206 455567777777788888887765 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 8.8e-05 0.28 23 70 .. 85 132 .. 69 148 .. 0.87 2 ? 0.3 0.0 0.31 9.8e+02 40 69 .. 173 202 .. 160 211 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.8e-05 TFIID-31kDa 23 yeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA r FUN_000070-T1 85 FQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIR 132 78889999***********************************96655 PP == domain 2 score: 0.3 bits; conditional E-value: 0.31 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000070-T1 173 AEILELAGNAARDNKKSRIIPRHLQLAVRN 202 689999999999999999999999999975 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 4.3e-05 0.14 35 77 .] 51 93 .. 49 93 .. 0.92 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.3e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000070-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66677889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.27u 0.43s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2329.12 // Query: FUN_000071-T1 [L=139] Description: FUN_000071 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000071-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000071-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000071-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000071-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000071-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000071-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000071-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000071-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000071-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1390.80 // Query: FUN_000072-T1 [L=129] Description: FUN_000072 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000072-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000072-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000072-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000072-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1307.75 // Query: FUN_000073-T1 [L=139] Description: FUN_000073 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000073-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000073-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000073-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000073-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000073-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000073-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000073-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000073-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000073-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.35s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1411.97 // Query: FUN_000074-T1 [L=272] Description: FUN_000074 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-39 135.1 4.6 6.9e-19 68.5 0.4 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 1.7e-18 67.0 0.3 5e-08 33.2 0.0 2.2 2 Histone_ABTB Histone domain in ABTB family protein 1.5e-08 35.3 0.5 0.012 16.3 0.0 2.8 3 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.1e-06 28.3 0.4 0.088 13.2 0.1 2.1 2 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.00011 22.8 1.7 0.36 11.3 0.2 2.2 2 YscO-like YscO-like protein 0.0002 22.3 0.0 1.5 9.9 0.0 2.4 2 TFIID_20kDa Transcription initiation factor TFIID subunit 0.0013 19.1 2.8 0.97 9.7 0.2 2.1 2 DUF5096 Domain of unknown function (DUF5096) ------ inclusion threshold ------ 0.018 15.7 0.0 11 6.8 0.0 2.4 2 Diphtheria_T Diphtheria toxin, T domain 0.072 13.2 0.0 21 5.3 0.0 2.3 2 Arm_3 Atypical Arm repeat 0.073 13.6 3.5 23 5.6 0.0 3.4 3 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain 0.087 13.0 0.1 17 5.6 0.0 2.4 2 LUC7 LUC7 N_terminus 0.17 12.6 0.0 37 5.1 0.0 2.4 2 SAM_CEP-1_C CEP-1 C-terminal SAM domain 0.21 12.3 0.0 45 4.9 0.0 2.4 2 DUF5367 Family of unknown function (DUF5367) 0.22 12.3 0.1 39 5.1 0.0 2.3 2 WHD_HELB DNA helicase B winged helix domain 0.37 11.8 9.7 3.4 8.7 1.2 2.3 2 PHF20_AT-hook PHD finger protein 20, AT-hook Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.5 0.4 4e-22 6.9e-19 7 88 .] 23 100 .. 17 100 .. 0.94 2 ! 68.5 0.4 4e-22 6.9e-19 7 88 .] 170 247 .. 164 247 .. 0.94 Alignments for each domain: == domain 1 score: 68.5 bits; conditional E-value: 4e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000074-T1 23 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 57788899999*****************....************************************************97 PP == domain 2 score: 68.5 bits; conditional E-value: 4e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000074-T1 170 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 247 57788899999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.2 0.0 3e-11 5e-08 10 91 .. 44 124 .. 39 134 .. 0.83 2 ! 32.1 0.0 6.4e-11 1.1e-07 10 91 .. 191 271 .. 186 272 .] 0.84 Alignments for each domain: == domain 1 score: 33.2 bits; conditional E-value: 3e-11 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000074-T1 44 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 124 5555444333...688889999999999*************99998763378*****************************987 PP == domain 2 score: 32.1 bits; conditional E-value: 6.4e-11 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000074-T1 191 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 271 5555444333...688889999999999*************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 7.2e-06 0.012 8 65 .] 41 98 .. 40 98 .. 0.95 2 ? -2.6 0.0 5.6 9.6e+03 31 56 .. 109 134 .. 105 136 .. 0.63 3 ! 16.3 0.0 7.2e-06 0.012 8 65 .] 188 245 .. 187 245 .. 0.95 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 7.2e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000074-T1 41 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 98 6799****88888.*****************************************9996 PP == domain 2 score: -2.6 bits; conditional E-value: 5.6 CBFD_NFYB_HMF 31 ecveefieevaseAaeickkekrKTi 56 +v+e + v++ ++++ + rK + FUN_000074-T1 109 HAVSEGTKAVTKYTSSKSPFDARKMV 134 45666666677777777777777765 PP == domain 3 score: 16.3 bits; conditional E-value: 7.2e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000074-T1 188 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 245 6799****88888.*****************************************9996 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 5.5e-05 0.094 42 117 .. 24 101 .. 5 104 .. 0.79 2 ! 13.2 0.1 5.2e-05 0.088 42 117 .. 171 248 .. 150 251 .. 0.78 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.5e-05 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000074-T1 24 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 101 233333445566778899999*******************98765266656788*********************998 PP == domain 2 score: 13.2 bits; conditional E-value: 5.2e-05 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000074-T1 171 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 248 233333445566778899999*******************98765266656788*********************998 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.2 0.00021 0.36 39 113 .. 24 100 .. 2 120 .. 0.74 2 ! 10.8 0.1 0.0003 0.52 40 113 .. 172 247 .. 150 261 .. 0.76 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00021 YscO-like 39 akleaerdkvlkhkkaKlqq.lrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 + + r k+++ + + + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_000074-T1 24 ETAKRRRGKRKESYAIYIYKvLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 33344455555666666666454424599****************************************99988655 PP == domain 2 score: 10.8 bits; conditional E-value: 0.0003 YscO-like 40 kleaerdkvlkhkkaKlqq.lrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 + r k+++ + + + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_000074-T1 172 TAKRRRGKRKESYAIYIYKvLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 247 3344455555555555555444414599****************************************99988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.0 0.00088 1.5 7 60 .. 43 96 .. 40 100 .. 0.93 2 ! 9.9 0.0 0.00088 1.5 7 60 .. 190 243 .. 187 247 .. 0.93 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00088 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000074-T1 43 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 96 5789************************************************95 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00088 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000074-T1 190 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 243 5789************************************************95 PP >> DUF5096 Domain of unknown function (DUF5096) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.2 0.00057 0.97 27 73 .. 36 87 .. 31 101 .. 0.78 2 ! 9.7 0.2 0.00059 1 27 73 .. 183 234 .. 178 247 .. 0.78 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00057 DUF5096 27 iaalnllkllknif...sssakieiiigg..ddiyneIglilgRlllakgyd 73 + a++++k+lk++ + s+k + i+++ +di+ +I++ +Rl+l +++ FUN_000074-T1 36 SYAIYIYKVLKQVHpdtGISSKAMGIMNSfvNDIFERIAVESSRLSLYNKKA 87 67999*******99999666666655554459***************99544 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00059 DUF5096 27 iaalnllkllknif...sssakieiiigg..ddiyneIglilgRlllakgyd 73 + a++++k+lk++ + s+k + i+++ +di+ +I++ +Rl+l +++ FUN_000074-T1 183 SYAIYIYKVLKQVHpdtGISSKAMGIMNSfvNDIFERIAVESSRLSLYNKKA 234 67999*******99999666666655554459***************99554 PP >> Diphtheria_T Diphtheria toxin, T domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.0063 11 109 133 .. 57 81 .. 21 87 .. 0.86 2 ? 6.8 0.0 0.0063 11 109 133 .. 204 228 .. 168 234 .. 0.86 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0063 Diphtheria_T 109 salGiadgivkhdteeiavnsiaLs 133 +a+Gi ++ v++ e iav+s Ls FUN_000074-T1 57 KAMGIMNSFVNDIFERIAVESSRLS 81 69******************98887 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0063 Diphtheria_T 109 salGiadgivkhdteeiavnsiaLs 133 +a+Gi ++ v++ e iav+s Ls FUN_000074-T1 204 KAMGIMNSFVNDIFERIAVESSRLS 228 69******************98887 PP >> Arm_3 Atypical Arm repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.012 21 20 41 .. 47 68 .. 47 77 .. 0.89 2 ? 5.3 0.0 0.012 21 20 41 .. 194 215 .. 194 224 .. 0.89 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.012 Arm_3 20 QeHeneeIYkkAlkIiekYFse 41 Q H + I+ kA+ I+ ++ ++ FUN_000074-T1 47 QVHPDTGISSKAMGIMNSFVND 68 889999*************987 PP == domain 2 score: 5.3 bits; conditional E-value: 0.012 Arm_3 20 QeHeneeIYkkAlkIiekYFse 41 Q H + I+ kA+ I+ ++ ++ FUN_000074-T1 194 QVHPDTGISSKAMGIMNSFVND 215 889999*************987 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.013 23 33 60 .. 72 99 .. 66 100 .. 0.88 2 ? 1.0 0.3 0.38 6.4e+02 37 65 .] 149 177 .. 148 177 .. 0.87 3 ? 5.6 0.0 0.013 23 33 60 .. 219 246 .. 213 247 .. 0.88 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.013 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000074-T1 72 RIAVESSRLSLYNKKATISSREIQTAIR 99 4678**********************96 PP == domain 2 score: 1.0 bits; conditional E-value: 0.38 LonB_AAA-LID 37 EAdywAreegaevveaehVekAleekeyR 65 E+++ A ++g+++v ++ +A +k++R FUN_000074-T1 149 ESNVAAAKKGEKRVGKAKSGTAETAKRRR 177 99************999888887777776 PP == domain 3 score: 5.6 bits; conditional E-value: 0.013 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000074-T1 219 RIAVESSRLSLYNKKATISSREIQTAIR 246 4678**********************96 PP >> LUC7 LUC7 N_terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.0098 17 76 120 .. 49 93 .. 11 120 .. 0.84 2 ? 5.1 0.0 0.014 24 76 120 .. 196 240 .. 181 249 .. 0.79 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.0098 LUC7 76 kkkygyeeellrflekliedvdrkiekakerlektqeekekeeek 120 + ++g +++ ++++++d+ ++i+ + +rl++ +++ + ++++ FUN_000074-T1 49 HPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSRE 93 4457888999***********************988777655544 PP == domain 2 score: 5.1 bits; conditional E-value: 0.014 LUC7 76 kkkygyeeellrflekliedvdrkiekakerlektqeekekeeek 120 + ++g +++ ++++++d+ ++i+ + +rl++ +++ + ++++ FUN_000074-T1 196 HPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSRE 240 4457888999***********************988776655444 PP >> SAM_CEP-1_C CEP-1 C-terminal SAM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.022 37 67 93 .. 61 85 .. 46 88 .. 0.88 2 ? 5.1 0.0 0.022 37 67 93 .. 208 232 .. 193 235 .. 0.88 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.022 SAM_CEP-1_C 67 LlkaFekdsdiFeklgidsekieklyk 93 +++ F + diFe++ ++s+ ++ ++k FUN_000074-T1 61 IMNSFVN--DIFERIAVESSRLSLYNK 85 6777777..************999886 PP == domain 2 score: 5.1 bits; conditional E-value: 0.022 SAM_CEP-1_C 67 LlkaFekdsdiFeklgidsekieklyk 93 +++ F + diFe++ ++s+ ++ ++k FUN_000074-T1 208 IMNSFVN--DIFERIAVESSRLSLYNK 232 6777777..************999886 PP >> DUF5367 Family of unknown function (DUF5367) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.027 45 26 52 .. 80 106 .. 70 113 .. 0.89 2 ? 4.8 0.0 0.028 47 26 52 .. 227 253 .. 217 259 .. 0.89 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.027 DUF5367 26 lpvyrykklkkqerlkaavlialpgml 52 l +y++k ++ ++++a+ ++lpg l FUN_000074-T1 80 LSLYNKKATISSREIQTAIRLLLPGEL 106 679*********************976 PP == domain 2 score: 4.8 bits; conditional E-value: 0.028 DUF5367 26 lpvyrykklkkqerlkaavlialpgml 52 l +y++k ++ ++++a+ ++lpg l FUN_000074-T1 227 LSLYNKKATISSREIQTAIRLLLPGEL 253 679*********************976 PP >> WHD_HELB DNA helicase B winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.023 39 46 69 .. 34 57 .. 29 96 .. 0.76 2 ? 5.1 0.0 0.023 39 46 69 .. 181 204 .. 176 243 .. 0.76 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.023 WHD_HELB 46 lqknaLiiYekLkkecrekGhTyv 69 ++ a++iY+ Lk+ ++G FUN_000074-T1 34 KESYAIYIYKVLKQVHPDTGISSK 57 6778**********9998886554 PP == domain 2 score: 5.1 bits; conditional E-value: 0.023 WHD_HELB 46 lqknaLiiYekLkkecrekGhTyv 69 ++ a++iY+ Lk+ ++G FUN_000074-T1 181 KESYAIYIYKVLKQVHPDTGISSK 204 6778**********9998886554 PP >> PHF20_AT-hook PHD finger protein 20, AT-hook # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 1.8 0.0055 9.4 62 88 .. 7 33 .. 3 39 .. 0.90 2 ? 8.7 1.2 0.002 3.4 60 88 .. 152 180 .. 146 186 .. 0.88 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0055 PHF20_AT-hook 62 vdkksesdivKksQenlkeaKRkRgrp 88 + kk e+ ++K + ++ aKR+Rg+ FUN_000074-T1 7 AAKKGEKRVGKAKSGTAETAKRRRGKR 33 679**********************85 PP == domain 2 score: 8.7 bits; conditional E-value: 0.002 PHF20_AT-hook 60 tqvdkksesdivKksQenlkeaKRkRgrp 88 + kk e+ ++K + ++ aKR+Rg+ FUN_000074-T1 152 VAAAKKGEKRVGKAKSGTAETAKRRRGKR 180 5678***********************85 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 448 (0.0175377); expected 510.9 (0.02) Passed bias filter: 261 (0.0102173); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.42 # Mc/sec: 2635.60 // Query: FUN_000075-T1 [L=179] Description: FUN_000075 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.1e-51 170.7 0.1 1.4e-32 112.4 0.2 2.0 2 Histone Core histone H2A/H2B/H3/H4 domain 3.2e-10 40.6 0.0 6.2e-05 23.7 0.0 2.1 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 3.1e-05 24.1 0.1 8.2e-05 22.8 0.0 1.7 2 Histone_ABTB Histone domain in ABTB family protein 5.1e-05 23.8 0.1 0.00012 22.7 0.0 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00075 20.3 0.1 0.0027 18.6 0.0 1.8 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.021 15.2 0.0 0.04 14.3 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.023 15.3 0.1 0.25 11.9 0.0 2.0 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.0 1.2e-18 4.2e-15 9 87 .. 11 88 .. 5 89 .. 0.94 2 ! 112.4 0.2 3.9e-36 1.4e-32 14 88 .] 100 174 .. 94 174 .. 0.98 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 1.2e-18 Histone 9 irkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000075-T1 11 GTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 88 67899999*****************8.89999**********************************************9 PP == domain 2 score: 112.4 bits; conditional E-value: 3.9e-36 Histone 14 kstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 kst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000075-T1 100 KSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 174 79************************************************************************7 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 1.7e-08 6.2e-05 2 65 .] 24 87 .. 23 87 .. 0.98 2 ! 15.1 0.0 8.4e-06 0.031 2 64 .. 108 171 .. 107 171 .. 0.93 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 1.7e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000075-T1 24 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 87 69************************************************************98 PP == domain 2 score: 15.1 bits; conditional E-value: 8.4e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000075-T1 108 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 171 7888888887888889999******************************************998 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.0 2.2e-08 8.2e-05 94 136 .] 11 53 .. 6 53 .. 0.89 2 ? -2.0 0.0 0.96 3.5e+03 23 48 .. 128 153 .. 107 174 .. 0.56 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 2.2e-08 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000075-T1 11 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 53 4457899**************************9999999875 PP == domain 2 score: -2.0 bits; conditional E-value: 0.96 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqR 48 ++ ++v l + + Lv + ++++ FUN_000075-T1 128 FQSSAVLALQEASEAYLVGLFEDTNL 153 45555555555555556655555543 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.6 9.5e+03 16 37 .. 65 84 .. 54 92 .. 0.61 2 ! 22.7 0.0 3.2e-08 0.00012 11 77 .. 113 173 .. 103 177 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 16 lakrfarasaiskaklskeale 37 la ++ar +k ++ + +l+ FUN_000075-T1 65 LAGNAARD--NKKSRIIPRHLQ 84 44455444..456666666665 PP == domain 2 score: 22.7 bits; conditional E-value: 3.2e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000075-T1 113 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 173 3455555555.....47899****************************************86.4555 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.72 2.6e+03 53 75 .. 70 92 .. 20 93 .. 0.65 2 ! 18.6 0.0 7.4e-07 0.0027 14 71 .. 114 173 .. 108 176 .. 0.83 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.72 CENP-S 53 AkHAkRstittdDvlLlaRrnes 75 A+ k+s i + + L +R++e+ FUN_000075-T1 70 ARDNKKSRIIPRHLQLAVRNDEE 92 45556666767777777777665 PP == domain 2 score: 18.6 bits; conditional E-value: 7.4e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000075-T1 114 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 173 444433311666789999*************************************99876 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 1.1e-05 0.04 24 77 .] 80 136 .. 64 136 .. 0.79 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.1e-05 YebU_pre-PUA_dom 24 deeleLWqR.Dkei..WLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 +++l+L R D+e+ L +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000075-T1 80 PRHLQLAVRnDEELnkLLAGKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 136 5566666552455532466789999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.13 4.8e+02 40 69 .. 60 89 .. 40 106 .. 0.86 2 ? 11.9 0.0 6.8e-05 0.25 22 68 .. 127 173 .. 112 178 .. 0.87 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.13 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000075-T1 60 AEILELAGNAARDNKKSRIIPRHLQLAVRN 89 689999999999999999999999999976 PP == domain 2 score: 11.9 bits; conditional E-value: 6.8e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000075-T1 127 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 173 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 510 (0.0199648); expected 510.9 (0.02) Passed bias filter: 423 (0.016559); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1755.92 // Query: FUN_000076-T1 [L=224] Description: FUN_000076 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-25 90.0 1.6 4.6e-19 69.1 0.4 2.3 2 Histone Core histone H2A/H2B/H3/H4 domain 5.3e-09 36.7 0.6 0.0042 17.8 0.1 2.6 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) 1.4e-08 34.9 0.8 7.4e-08 32.6 0.0 2.0 2 Histone_ABTB Histone domain in ABTB family protein 4.4e-06 27.2 0.1 0.00011 22.8 0.1 2.4 2 CENP-T_C Centromere kinetochore component CENP-T hist 8.2e-05 23.2 0.2 0.00048 20.7 0.0 2.2 2 TAF TATA box binding protein associated factor ( 0.00026 21.5 0.1 0.012 16.2 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD su 0.0026 18.6 0.0 0.012 16.4 0.0 2.0 2 CENP-S CENP-S protein 0.0036 18.2 0.1 1.1 10.3 0.0 2.4 2 TFIID_20kDa Transcription initiation factor TFIID subuni 0.0098 16.4 0.1 5.9 7.5 0.0 2.7 2 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain ------ inclusion threshold ------ 0.014 15.9 0.2 0.02 15.3 0.2 1.2 1 Intron_maturas2 Type II intron maturase 0.014 15.8 0.1 0.021 15.2 0.1 1.3 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repe 0.2 12.2 0.1 0.45 11.0 0.1 1.6 1 Bromo_TP Bromodomain associated Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.0 4.1e-07 0.00088 54 86 .. 59 91 .. 18 92 .. 0.91 2 ! 69.1 0.4 2.2e-22 4.6e-19 7 88 .] 122 199 .. 116 199 .. 0.94 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 4.1e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAv 86 ++ +l+ + ++A +++haKR+T+t+ D+ A+ FUN_000076-T1 59 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 788*************************98875 PP == domain 2 score: 69.1 bits; conditional E-value: 2.2e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000076-T1 122 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 199 57788999999*****************....************************************************97 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 2e-06 0.0042 32 65 .] 58 91 .. 32 91 .. 0.84 2 ! 16.8 0.0 4.1e-06 0.0087 8 65 .] 140 197 .. 139 197 .. 0.95 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 2e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000076-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 5778*************************98876 PP == domain 2 score: 16.8 bits; conditional E-value: 4.1e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000076-T1 140 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 197 6799****88888.*****************************************9996 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.1 0.21 4.5e+02 27 82 .. 51 108 .. 26 132 .. 0.59 2 ! 32.6 0.0 3.5e-11 7.4e-08 10 91 .. 143 223 .. 138 224 .] 0.84 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.21 Histone_ABTB 27 vvkrlsallqraLvriareaqRLskllakctke..evksavklvlseslaesCikaav 82 + ++ +l++ L ++ r+a +++ ++ t + +v +a++ ++ + +C aa FUN_000076-T1 51 IYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTamDVVYALNSSSFRTASCKCRAAAK 108 4444455666666666666666666655544430044444443333444445555555 PP == domain 2 score: 32.6 bits; conditional E-value: 3.5e-11 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000076-T1 143 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 223 5555544333...788899999999999*************99998763378****************************9865 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.1 5.1e-08 0.00011 28 75 .. 44 91 .. 17 109 .. 0.79 2 ? 2.2 0.0 0.12 2.6e+02 29 74 .. 151 196 .. 139 209 .. 0.84 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 5.1e-08 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLl 75 +++s e +++ f+e v D +y++HA+RKt+ Dv+ l FUN_000076-T1 44 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 446666667777778899**************************9765 PP == domain 2 score: 2.2 bits; conditional E-value: 0.12 CENP-T_C 29 aklskealealeqasewffeqvseDLeayakHAgRKtidesDvllL 74 + +s +a+ +++ + fe+++ + +++ ++ ti ++++ + FUN_000076-T1 151 TGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTA 196 5688999999999999999*99999888888888888888877665 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 2.2e-07 0.00048 35 65 .. 61 91 .. 27 92 .. 0.78 2 ? -0.2 0.0 0.76 1.6e+03 38 66 .] 170 198 .. 151 198 .. 0.80 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 2.2e-07 TAF 35 yrlkeivqeaakfmrhskRrkLtvaDvdsAL 65 l +++++a+ +++h+kR++ t+ Dv +AL FUN_000076-T1 61 VFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 55889**********************9998 PP == domain 2 score: -0.2 bits; conditional E-value: 0.76 TAF 38 keivqeaakfmrhskRrkLtvaDvdsALr 66 +i+ e+++ k +++++ ++ A+r FUN_000076-T1 170 ERIAVESSRLSLYNKKATISSREIQTAIR 198 56778888888888999999999999998 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 5.7e-06 0.012 38 70 .. 62 94 .. 34 102 .. 0.86 2 ? 3.4 0.0 0.052 1.1e+02 39 70 .. 169 200 .. 141 213 .. 0.79 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 5.7e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++s FUN_000076-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALNSS 94 6789*************************9875 PP == domain 2 score: 3.4 bits; conditional E-value: 0.052 TFIID-31kDa 39 ttevledAkvysehakkkkidlddvrlAiqsr 70 + +++ +s ++kk++i+ ++++Ai FUN_000076-T1 169 FERIAVESSRLSLYNKKATISSREIQTAIRLL 200 455667899999999**************875 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 5.7e-06 0.012 42 67 .. 63 88 .. 41 94 .. 0.88 2 ? -1.1 0.0 1.8 3.7e+03 26 49 .. 153 179 .. 137 196 .. 0.50 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 5.7e-06 CENP-S 42 lenlakDLeaFAkHAkRstittdDvl 67 len+ +D ++ +HAkR+t+t+ Dv+ FUN_000076-T1 63 LENVIRDAVTYTEHAKRKTVTAMDVV 88 789999*******************7 PP == domain 2 score: -1.1 bits; conditional E-value: 1.8 CENP-S 26 vtpqfi...aaltelvykqlenlakDL 49 ++++++ ++ ++ ++++++ ++ L FUN_000076-T1 153 ISSKAMgimNSFVNDIFERIAVESSRL 179 444444001333333344444333334 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.018 39 33 62 .. 62 91 .. 57 94 .. 0.90 2 ! 10.3 0.0 0.0005 1.1 7 60 .. 142 195 .. 139 199 .. 0.93 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.018 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhl 62 F e+v+ a+ h k +++ + D+ + l FUN_000076-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 99***********************98777 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0005 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000076-T1 142 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 195 5789************************************************95 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0028 5.9 32 65 .] 64 97 .. 62 97 .. 0.91 2 ! 6.1 0.0 0.0078 17 33 60 .. 171 198 .. 164 199 .. 0.88 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0028 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAleekeyR 65 ++++r A ++ +++++++v+a +V Al+ +R FUN_000076-T1 64 ENVIRDAVTYTEHAKRKTVTAMDVVYALNSSSFR 97 789999**********************988777 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0078 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000076-T1 171 RIAVESSRLSLYNKKATISSREIQTAIR 198 4678**********************96 PP >> Intron_maturas2 Type II intron maturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.2 9.5e-06 0.02 32 109 .. 44 121 .. 27 152 .. 0.83 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 9.5e-06 Intron_maturas2 32 PrsvlrwidledrdIllry.kaiirgllnYYsfasnkkrlrerikyilrkscvkTLArKlklktvrkvikkfGkklsdl 109 +++ +i++e+r +l+ + + +ir + Y a++k+ + + y l+ s +T K + +k k+ Gk s FUN_000076-T1 44 VKRISGLIYEETRGVLKVFlENVIRDAVTYTEHAKRKTVTAMDVVYALNSSSFRTASCKCRA-AAKKGEKRVGKAKSGT 121 5678899**********99457*******************9*******************9.9999999999544433 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 1e-05 0.021 25 117 .. 105 200 .. 83 204 .. 0.70 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1e-05 ARM_TT21 25 eAlktLktAlklpg.kkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 A+k ++ + ++ + +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000076-T1 105 AAAKKGEKRVGKAKsGTAETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 200 444333333332221222333344445567778899999*******************98765266656788**********************98 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.00021 0.45 34 70 .. 57 93 .. 52 100 .. 0.87 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00021 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L+ FUN_000076-T1 57 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALNS 93 56778999999*********************99975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 853 (0.0333921); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 2200.10 // Query: FUN_000077-T1 [L=164] Description: FUN_000077 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000077-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000077-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000077-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1676.62 // Query: FUN_000078-T1 [L=129] Description: FUN_000078 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000078-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000078-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000078-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000078-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1297.18 // Query: FUN_000079-T1 [L=139] Description: FUN_000079 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000079-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000079-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000079-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000079-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000079-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000079-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000079-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000079-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000079-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.35s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1393.67 // Query: FUN_000080-T1 [L=129] Description: FUN_000080 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000080-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000080-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000080-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000080-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1277.26 // Query: FUN_000081-T1 [L=238] Description: FUN_000081 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-54 181.7 0.1 4.2e-38 130.1 0.2 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 1.6e-20 73.0 1.7 3.6e-20 71.9 1.7 1.7 1 Histone_H2A_C C-terminus of histone H2A 7.8e-10 39.4 0.0 0.00011 22.9 0.0 2.4 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 6.2e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 CENP-T_C Centromere kinetochore component CENP-T his 0.00089 20.5 0.9 0.0014 19.9 0.9 1.3 1 PAF PCNA-associated factor histone like domain 0.0015 19.3 0.1 0.0045 17.9 0.0 1.7 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.033 14.7 0.1 0.28 11.7 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD s 0.065 13.6 0.0 0.14 12.6 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.1 0.2 1.3e-41 4.2e-38 1 88 [] 44 131 .. 44 131 .. 0.99 2 ! 49.5 0.0 1.8e-16 5.8e-13 21 87 .. 136 201 .. 132 202 .. 0.95 Alignments for each domain: == domain 1 score: 130.1 bits; conditional E-value: 1.3e-41 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000081-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 131 689************************************************************************************7 PP == domain 2 score: 49.5 bits; conditional E-value: 1.8e-16 Histone 21 qklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000081-T1 136 LQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 201 689**********8.89999**********************************************9 PP >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.9 1.7 1.1e-23 3.6e-20 1 34 [. 204 237 .. 204 238 .] 0.97 Alignments for each domain: == domain 1 score: 71.9 bits; conditional E-value: 1.1e-23 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000081-T1 204 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 237 9*******************************96 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 1.7e-05 0.054 2 64 .. 65 128 .. 64 128 .. 0.93 2 ! 22.9 0.0 3.4e-08 0.00011 2 65 .] 137 200 .. 136 200 .. 0.98 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.7e-05 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000081-T1 65 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 128 7888888887888889999******************************************998 PP == domain 2 score: 22.9 bits; conditional E-value: 3.4e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000081-T1 137 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 200 69************************************************************98 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.3e-08 0.00017 11 77 .. 70 130 .. 59 143 .. 0.83 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.3e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000081-T1 70 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 130 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.9 4.3e-07 0.0014 1 62 [. 1 58 [. 1 80 [. 0.90 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 4.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000081-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 58 99***998...9***************999999999988899999998.6999999999996 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-06 0.0045 14 71 .. 71 130 .. 65 134 .. 0.83 2 ? -2.0 0.0 2.1 6.7e+03 53 76 .] 183 206 .. 160 206 .. 0.71 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-06 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000081-T1 71 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 444433311666789999*************************************99876 PP == domain 2 score: -2.0 bits; conditional E-value: 2.1 CENP-S 53 AkHAkRstittdDvlLlaRrnesL 76 A+ k+s i + + L +R++e+L FUN_000081-T1 183 ARDNKKSRIIPRHLQLAVRNDEEL 206 455567777777788888887765 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 8.8e-05 0.28 23 70 .. 85 132 .. 69 148 .. 0.87 2 ? 0.3 0.0 0.31 9.8e+02 40 69 .. 173 202 .. 160 211 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.8e-05 TFIID-31kDa 23 yeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA r FUN_000081-T1 85 FQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIR 132 78889999***********************************96655 PP == domain 2 score: 0.3 bits; conditional E-value: 0.31 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000081-T1 173 AEILELAGNAARDNKKSRIIPRHLQLAVRN 202 689999999999999999999999999975 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 4.3e-05 0.14 35 77 .] 51 93 .. 49 93 .. 0.92 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.3e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000081-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66677889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.32u 0.35s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2372.95 // Query: FUN_000082-T1 [L=136] Description: FUN_000082 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-39 132.6 0.2 1e-38 132.1 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.9e-05 24.2 0.6 5.8e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00028 22.1 0.7 0.00032 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00094 20.0 0.0 0.0014 19.4 0.0 1.2 1 CENP-S CENP-S protein 0.0083 16.9 0.0 0.016 15.9 0.0 1.5 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.028 14.8 0.0 0.049 14.0 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.069 13.7 0.2 0.14 12.7 0.0 1.5 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.1 0.2 2.8e-42 1e-38 1 88 [] 44 131 .. 44 131 .. 0.99 Alignments for each domain: == domain 1 score: 132.1 bits; conditional E-value: 2.8e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000082-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 131 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.7 9.8e+03 14 25 .. 19 30 .. 15 38 .. 0.63 2 ! 23.6 0.1 1.6e-08 5.8e-05 11 77 .. 70 130 .. 57 134 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.7 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000082-T1 19 KQLATKAARKSA 30 455556555554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.6e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000082-T1 70 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 130 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 8.7e-08 0.00032 1 62 [. 1 58 [. 1 88 [. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 8.7e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000082-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 58 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 4e-07 0.0014 14 71 .. 71 130 .. 65 133 .. 0.83 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 4e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000082-T1 71 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.5e-06 0.016 2 64 .. 65 128 .. 64 128 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.5e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000082-T1 65 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 128 789999888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 1.3e-05 0.049 35 77 .] 51 93 .. 48 93 .. 0.93 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.3e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000082-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 2.3 8.4e+03 74 90 .. 11 27 .. 5 33 .. 0.62 2 ? 12.7 0.0 3.8e-05 0.14 22 68 .. 84 130 .. 69 135 .. 0.87 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 2.3 TFIID-31kDa 74 sftepppkelLlelAre 90 s ++ p++ L++ A++ FUN_000082-T1 11 STGGKAPRKQLATKAAR 27 55566677777666654 PP == domain 2 score: 12.7 bits; conditional E-value: 3.8e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000082-T1 84 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (136 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 498 (0.019495); expected 510.9 (0.02) Passed bias filter: 378 (0.0147974); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1382.32 // Query: FUN_000083-T1 [L=129] Description: FUN_000083 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000083-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000083-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000083-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000083-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1281.17 // Query: FUN_000084-T1 [L=164] Description: FUN_000084 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000084-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000084-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000084-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1620.74 // Query: FUN_000085-T1 [L=129] Description: FUN_000085 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000085-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000085-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000085-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000085-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1295.15 // Query: FUN_000086-T1 [L=164] Description: FUN_000086 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000086-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000086-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000086-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1642.65 // Query: FUN_000087-T1 [L=129] Description: FUN_000087 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000087-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000087-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000087-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000087-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.35s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1279.17 // Query: FUN_000088-T1 [L=164] Description: FUN_000088 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000088-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000088-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000088-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1639.88 // Query: FUN_000089-T1 [L=129] Description: FUN_000089 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000089-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000089-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000089-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000089-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1295.83 // Query: FUN_000090-T1 [L=164] Description: FUN_000090 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000090-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000090-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000090-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1656.07 // Query: FUN_000091-T1 [L=129] Description: FUN_000091 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000091-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000091-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000091-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000091-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1289.17 // Query: FUN_000092-T1 [L=164] Description: FUN_000092 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000092-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000092-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000092-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1622.11 // Query: FUN_000093-T1 [L=129] Description: FUN_000093 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000093-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000093-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000093-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000093-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1290.69 // Query: FUN_000094-T1 [L=164] Description: FUN_000094 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000094-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000094-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000094-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1657.12 // Query: FUN_000095-T1 [L=129] Description: FUN_000095 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000095-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000095-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000095-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000095-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1304.60 // Query: FUN_000096-T1 [L=164] Description: FUN_000096 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000096-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000096-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000096-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1613.08 // Query: FUN_000097-T1 [L=129] Description: FUN_000097 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000097-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000097-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000097-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000097-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1332.82 // Query: FUN_000098-T1 [L=164] Description: FUN_000098 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000098-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000098-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000098-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1612.17 // Query: FUN_000099-T1 [L=129] Description: FUN_000099 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000099-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000099-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000099-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000099-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1342.55 // Query: FUN_000100-T1 [L=164] Description: FUN_000100 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000100-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000100-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000100-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1707.87 // Query: FUN_000101-T1 [L=129] Description: FUN_000101 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000101-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000101-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000101-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000101-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1305.34 // Query: FUN_000102-T1 [L=164] Description: FUN_000102 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000102-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000102-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000102-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1618.19 // Query: FUN_000103-T1 [L=129] Description: FUN_000103 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-21 74.1 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 3.8e-05 23.8 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000103-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000103-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000103-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 5.9e-09 3.8e-05 94 136 .] 15 57 .. 5 57 .. 0.88 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 5.9e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000103-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 532 (0.020826); expected 510.9 (0.02) Passed bias filter: 446 (0.0174594); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1310.88 // Query: FUN_000104-T1 [L=139] Description: FUN_000104 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000104-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000104-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000104-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000104-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000104-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000104-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000104-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000104-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000104-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1416.64 // Query: FUN_000105-T1 [L=129] Description: FUN_000105 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000105-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000105-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000105-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000105-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1289.17 // Query: FUN_000106-T1 [L=139] Description: FUN_000106 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000106-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000106-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000106-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000106-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000106-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000106-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000106-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000106-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000106-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1433.77 // Query: FUN_000107-T1 [L=267] Description: FUN_000107 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-39 135.1 4.6 6.7e-19 68.6 0.4 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 5.3e-17 62.2 0.1 1.1e-07 32.1 0.0 2.2 2 Histone_ABTB Histone domain in ABTB family protein 1.3e-08 35.4 0.2 0.012 16.4 0.0 2.6 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2e-06 28.4 0.4 0.085 13.3 0.1 2.1 2 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 6.1e-05 23.6 0.9 0.34 11.4 0.1 2.2 2 YscO-like YscO-like protein 0.00019 22.3 0.0 1.5 9.9 0.0 2.4 2 TFIID_20kDa Transcription initiation factor TFIID subunit 0.0012 19.2 2.8 0.94 9.8 0.2 2.1 2 DUF5096 Domain of unknown function (DUF5096) ------ inclusion threshold ------ 0.017 15.8 0.0 10 6.8 0.0 2.4 2 Diphtheria_T Diphtheria toxin, T domain 0.068 13.7 3.5 22 5.7 0.0 3.4 3 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain 0.07 13.2 0.0 20 5.3 0.0 2.3 2 Arm_3 Atypical Arm repeat 0.084 13.1 0.1 17 5.6 0.0 2.4 2 LUC7 LUC7 N_terminus 0.16 12.7 0.0 36 5.2 0.0 2.4 2 SAM_CEP-1_C CEP-1 C-terminal SAM domain 0.21 12.4 0.0 45 4.9 0.0 2.4 2 DUF5367 Family of unknown function (DUF5367) 0.21 12.4 0.1 37 5.1 0.0 2.3 2 WHD_HELB DNA helicase B winged helix domain 0.37 11.8 9.7 3.3 8.7 1.2 2.3 2 PHF20_AT-hook PHD finger protein 20, AT-hook Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.6 0.4 3.9e-22 6.7e-19 7 88 .] 23 100 .. 17 100 .. 0.94 2 ! 68.6 0.4 3.9e-22 6.7e-19 7 88 .] 165 242 .. 159 242 .. 0.94 Alignments for each domain: == domain 1 score: 68.6 bits; conditional E-value: 3.9e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000107-T1 23 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 57788899999*****************....************************************************97 PP == domain 2 score: 68.6 bits; conditional E-value: 3.9e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000107-T1 165 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 242 57788899999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 0.0 1.1e-09 1.8e-06 10 86 .. 44 119 .. 39 123 .. 0.84 2 ! 32.1 0.0 6.2e-11 1.1e-07 10 91 .. 186 266 .. 181 267 .] 0.84 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 1.1e-09 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvs 86 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ FUN_000107-T1 44 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVT 119 5555444333...688889999999999*************99998763378*************************86 PP == domain 2 score: 32.1 bits; conditional E-value: 6.2e-11 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000107-T1 186 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 266 5555444333...688889999999999*************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 7e-06 0.012 8 65 .] 41 98 .. 40 98 .. 0.95 2 ! 16.4 0.0 7e-06 0.012 8 65 .] 183 240 .. 182 240 .. 0.95 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 7e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000107-T1 41 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 98 6799****88888.*****************************************9996 PP == domain 2 score: 16.4 bits; conditional E-value: 7e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000107-T1 183 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 240 6799****88888.*****************************************9996 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 5.3e-05 0.091 42 117 .. 24 101 .. 5 104 .. 0.79 2 ! 13.3 0.1 5e-05 0.085 42 117 .. 166 243 .. 145 246 .. 0.78 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 5.3e-05 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000107-T1 24 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 101 233333445566778899999*******************98765266656788*********************998 PP == domain 2 score: 13.3 bits; conditional E-value: 5e-05 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000107-T1 166 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 243 233333445566778899999*******************98765266656788*********************998 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.1 0.0002 0.34 39 113 .. 24 100 .. 2 115 .. 0.74 2 ! 10.9 0.1 0.00029 0.5 40 113 .. 167 242 .. 145 256 .. 0.76 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0002 YscO-like 39 akleaerdkvlkhkkaKlqq.lrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 + + r k+++ + + + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_000107-T1 24 ETAKRRRGKRKESYAIYIYKvLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 33344455555666666666454424599****************************************99988655 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00029 YscO-like 40 kleaerdkvlkhkkaKlqq.lrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 + r k+++ + + + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_000107-T1 167 TAKRRRGKRKESYAIYIYKvLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 242 3344455555555555555444414599****************************************99988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.0 0.00086 1.5 7 60 .. 43 96 .. 40 100 .. 0.93 2 ! 9.9 0.0 0.00086 1.5 7 60 .. 185 238 .. 182 242 .. 0.93 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00086 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000107-T1 43 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 96 5789************************************************95 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00086 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000107-T1 185 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 238 5789************************************************95 PP >> DUF5096 Domain of unknown function (DUF5096) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.2 0.00055 0.94 27 73 .. 36 87 .. 31 101 .. 0.78 2 ! 9.7 0.2 0.00057 0.98 27 73 .. 178 229 .. 173 242 .. 0.78 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00055 DUF5096 27 iaalnllkllknif...sssakieiiigg..ddiyneIglilgRlllakgyd 73 + a++++k+lk++ + s+k + i+++ +di+ +I++ +Rl+l +++ FUN_000107-T1 36 SYAIYIYKVLKQVHpdtGISSKAMGIMNSfvNDIFERIAVESSRLSLYNKKA 87 67999*******99999666666655554459***************99544 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00057 DUF5096 27 iaalnllkllknif...sssakieiiigg..ddiyneIglilgRlllakgyd 73 + a++++k+lk++ + s+k + i+++ +di+ +I++ +Rl+l +++ FUN_000107-T1 178 SYAIYIYKVLKQVHpdtGISSKAMGIMNSfvNDIFERIAVESSRLSLYNKKA 229 67999*******99999666666655554459***************99554 PP >> Diphtheria_T Diphtheria toxin, T domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.0061 10 109 133 .. 57 81 .. 20 87 .. 0.86 2 ? 6.8 0.0 0.0061 10 109 133 .. 199 223 .. 163 229 .. 0.86 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0061 Diphtheria_T 109 salGiadgivkhdteeiavnsiaLs 133 +a+Gi ++ v++ e iav+s Ls FUN_000107-T1 57 KAMGIMNSFVNDIFERIAVESSRLS 81 69******************98887 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0061 Diphtheria_T 109 salGiadgivkhdteeiavnsiaLs 133 +a+Gi ++ v++ e iav+s Ls FUN_000107-T1 199 KAMGIMNSFVNDIFERIAVESSRLS 223 69******************98887 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.013 22 33 60 .. 72 99 .. 66 100 .. 0.88 2 ? 1.0 0.3 0.37 6.3e+02 37 65 .] 144 172 .. 143 172 .. 0.87 3 ? 5.7 0.0 0.013 22 33 60 .. 214 241 .. 208 242 .. 0.88 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.013 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000107-T1 72 RIAVESSRLSLYNKKATISSREIQTAIR 99 4678**********************96 PP == domain 2 score: 1.0 bits; conditional E-value: 0.37 LonB_AAA-LID 37 EAdywAreegaevveaehVekAleekeyR 65 E+++ A ++g+++v ++ +A +k++R FUN_000107-T1 144 ESNVAAAKKGEKRVGKAKSGTAETAKRRR 172 99************999888887777777 PP == domain 3 score: 5.7 bits; conditional E-value: 0.013 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000107-T1 214 RIAVESSRLSLYNKKATISSREIQTAIR 241 4678**********************96 PP >> Arm_3 Atypical Arm repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.012 20 20 41 .. 47 68 .. 47 77 .. 0.89 2 ? 5.3 0.0 0.012 20 20 41 .. 189 210 .. 189 219 .. 0.89 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.012 Arm_3 20 QeHeneeIYkkAlkIiekYFse 41 Q H + I+ kA+ I+ ++ ++ FUN_000107-T1 47 QVHPDTGISSKAMGIMNSFVND 68 889999*************987 PP == domain 2 score: 5.3 bits; conditional E-value: 0.012 Arm_3 20 QeHeneeIYkkAlkIiekYFse 41 Q H + I+ kA+ I+ ++ ++ FUN_000107-T1 189 QVHPDTGISSKAMGIMNSFVND 210 889999*************987 PP >> LUC7 LUC7 N_terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.0099 17 76 120 .. 49 93 .. 11 116 .. 0.84 2 ? 5.1 0.0 0.014 23 76 120 .. 191 235 .. 176 244 .. 0.79 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.0099 LUC7 76 kkkygyeeellrflekliedvdrkiekakerlektqeekekeeek 120 + ++g +++ ++++++d+ ++i+ + +rl++ +++ + ++++ FUN_000107-T1 49 HPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSRE 93 4457888999***********************988777655444 PP == domain 2 score: 5.1 bits; conditional E-value: 0.014 LUC7 76 kkkygyeeellrflekliedvdrkiekakerlektqeekekeeek 120 + ++g +++ ++++++d+ ++i+ + +rl++ +++ + ++++ FUN_000107-T1 191 HPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSRE 235 4457888999***********************988776655444 PP >> SAM_CEP-1_C CEP-1 C-terminal SAM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.021 36 67 93 .. 61 85 .. 46 88 .. 0.88 2 ? 5.2 0.0 0.021 36 67 93 .. 203 227 .. 188 230 .. 0.88 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.021 SAM_CEP-1_C 67 LlkaFekdsdiFeklgidsekieklyk 93 +++ F + diFe++ ++s+ ++ ++k FUN_000107-T1 61 IMNSFVN--DIFERIAVESSRLSLYNK 85 6777777..************999886 PP == domain 2 score: 5.2 bits; conditional E-value: 0.021 SAM_CEP-1_C 67 LlkaFekdsdiFeklgidsekieklyk 93 +++ F + diFe++ ++s+ ++ ++k FUN_000107-T1 203 IMNSFVN--DIFERIAVESSRLSLYNK 227 6777777..************999886 PP >> DUF5367 Family of unknown function (DUF5367) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.026 45 26 52 .. 80 106 .. 69 112 .. 0.89 2 ? 4.9 0.0 0.026 45 26 52 .. 222 248 .. 211 254 .. 0.89 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.026 DUF5367 26 lpvyrykklkkqerlkaavlialpgml 52 l +y++k ++ ++++a+ ++lpg l FUN_000107-T1 80 LSLYNKKATISSREIQTAIRLLLPGEL 106 679*********************976 PP == domain 2 score: 4.9 bits; conditional E-value: 0.026 DUF5367 26 lpvyrykklkkqerlkaavlialpgml 52 l +y++k ++ ++++a+ ++lpg l FUN_000107-T1 222 LSLYNKKATISSREIQTAIRLLLPGEL 248 679*********************976 PP >> WHD_HELB DNA helicase B winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.022 37 46 69 .. 34 57 .. 29 96 .. 0.76 2 ? 5.1 0.0 0.022 37 46 69 .. 176 199 .. 171 238 .. 0.76 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.022 WHD_HELB 46 lqknaLiiYekLkkecrekGhTyv 69 ++ a++iY+ Lk+ ++G FUN_000107-T1 34 KESYAIYIYKVLKQVHPDTGISSK 57 6778**********9998886554 PP == domain 2 score: 5.1 bits; conditional E-value: 0.022 WHD_HELB 46 lqknaLiiYekLkkecrekGhTyv 69 ++ a++iY+ Lk+ ++G FUN_000107-T1 176 KESYAIYIYKVLKQVHPDTGISSK 199 6778**********9998886554 PP >> PHF20_AT-hook PHD finger protein 20, AT-hook # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 1.8 0.0054 9.1 62 88 .. 7 33 .. 3 39 .. 0.90 2 ? 8.7 1.2 0.002 3.3 60 88 .. 147 175 .. 141 181 .. 0.88 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0054 PHF20_AT-hook 62 vdkksesdivKksQenlkeaKRkRgrp 88 + kk e+ ++K + ++ aKR+Rg+ FUN_000107-T1 7 AAKKGEKRVGKAKSGTAETAKRRRGKR 33 679**********************85 PP == domain 2 score: 8.7 bits; conditional E-value: 0.002 PHF20_AT-hook 60 tqvdkksesdivKksQenlkeaKRkRgrp 88 + kk e+ ++K + ++ aKR+Rg+ FUN_000107-T1 147 VAAAKKGEKRVGKAKSGTAETAKRRRGKR 175 5678***********************85 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (267 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 610 (0.0238794); expected 510.9 (0.02) Passed bias filter: 386 (0.0151106); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2683.87 // Query: FUN_000108-T1 [L=179] Description: FUN_000108 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.1e-51 170.7 0.1 1.4e-32 112.4 0.2 2.0 2 Histone Core histone H2A/H2B/H3/H4 domain 3.2e-10 40.6 0.0 6.2e-05 23.7 0.0 2.1 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 3.1e-05 24.1 0.1 8.2e-05 22.8 0.0 1.7 2 Histone_ABTB Histone domain in ABTB family protein 5.1e-05 23.8 0.1 0.00012 22.7 0.0 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00075 20.3 0.1 0.0027 18.6 0.0 1.8 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.021 15.2 0.0 0.04 14.3 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.023 15.3 0.1 0.25 11.9 0.0 2.0 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.0 1.2e-18 4.2e-15 9 87 .. 11 88 .. 5 89 .. 0.94 2 ! 112.4 0.2 3.9e-36 1.4e-32 14 88 .] 100 174 .. 94 174 .. 0.98 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 1.2e-18 Histone 9 irkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000108-T1 11 GTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 88 67899999*****************8.89999**********************************************9 PP == domain 2 score: 112.4 bits; conditional E-value: 3.9e-36 Histone 14 kstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 kst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000108-T1 100 KSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 174 79************************************************************************7 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 1.7e-08 6.2e-05 2 65 .] 24 87 .. 23 87 .. 0.98 2 ! 15.1 0.0 8.4e-06 0.031 2 64 .. 108 171 .. 107 171 .. 0.93 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 1.7e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000108-T1 24 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 87 69************************************************************98 PP == domain 2 score: 15.1 bits; conditional E-value: 8.4e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000108-T1 108 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 171 7888888887888889999******************************************998 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.0 2.2e-08 8.2e-05 94 136 .] 11 53 .. 6 53 .. 0.89 2 ? -2.0 0.0 0.96 3.5e+03 23 48 .. 128 153 .. 107 174 .. 0.56 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 2.2e-08 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000108-T1 11 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 53 4457899**************************9999999875 PP == domain 2 score: -2.0 bits; conditional E-value: 0.96 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqR 48 ++ ++v l + + Lv + ++++ FUN_000108-T1 128 FQSSAVLALQEASEAYLVGLFEDTNL 153 45555555555555556655555543 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.6 9.5e+03 16 37 .. 65 84 .. 54 92 .. 0.61 2 ! 22.7 0.0 3.2e-08 0.00012 11 77 .. 113 173 .. 103 177 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 16 lakrfarasaiskaklskeale 37 la ++ar +k ++ + +l+ FUN_000108-T1 65 LAGNAARD--NKKSRIIPRHLQ 84 44455444..456666666665 PP == domain 2 score: 22.7 bits; conditional E-value: 3.2e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000108-T1 113 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 173 3455555555.....47899****************************************86.4555 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.72 2.6e+03 53 75 .. 70 92 .. 20 93 .. 0.65 2 ! 18.6 0.0 7.4e-07 0.0027 14 71 .. 114 173 .. 108 176 .. 0.83 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.72 CENP-S 53 AkHAkRstittdDvlLlaRrnes 75 A+ k+s i + + L +R++e+ FUN_000108-T1 70 ARDNKKSRIIPRHLQLAVRNDEE 92 45556666767777777777665 PP == domain 2 score: 18.6 bits; conditional E-value: 7.4e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000108-T1 114 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 173 444433311666789999*************************************99876 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 1.1e-05 0.04 24 77 .] 80 136 .. 64 136 .. 0.79 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.1e-05 YebU_pre-PUA_dom 24 deeleLWqR.Dkei..WLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 +++l+L R D+e+ L +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000108-T1 80 PRHLQLAVRnDEELnkLLAGKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 136 5566666552455532466789999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.13 4.8e+02 40 69 .. 60 89 .. 40 106 .. 0.86 2 ? 11.9 0.0 6.8e-05 0.25 22 68 .. 127 173 .. 112 178 .. 0.87 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.13 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000108-T1 60 AEILELAGNAARDNKKSRIIPRHLQLAVRN 89 689999999999999999999999999976 PP == domain 2 score: 11.9 bits; conditional E-value: 6.8e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000108-T1 127 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 173 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 510 (0.0199648); expected 510.9 (0.02) Passed bias filter: 423 (0.016559); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1764.65 // Query: FUN_000109-T1 [L=224] Description: FUN_000109 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-25 90.0 1.6 4.6e-19 69.1 0.4 2.3 2 Histone Core histone H2A/H2B/H3/H4 domain 5.3e-09 36.7 0.6 0.0042 17.8 0.1 2.6 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) 1.4e-08 34.9 0.8 7.4e-08 32.6 0.0 2.0 2 Histone_ABTB Histone domain in ABTB family protein 4.4e-06 27.2 0.1 0.00011 22.8 0.1 2.4 2 CENP-T_C Centromere kinetochore component CENP-T hist 8.2e-05 23.2 0.2 0.00048 20.7 0.0 2.2 2 TAF TATA box binding protein associated factor ( 0.00026 21.5 0.1 0.012 16.2 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD su 0.0026 18.6 0.0 0.012 16.4 0.0 2.0 2 CENP-S CENP-S protein 0.0036 18.2 0.1 1.1 10.3 0.0 2.4 2 TFIID_20kDa Transcription initiation factor TFIID subuni 0.0098 16.4 0.1 5.9 7.5 0.0 2.7 2 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain ------ inclusion threshold ------ 0.014 15.9 0.2 0.02 15.3 0.2 1.2 1 Intron_maturas2 Type II intron maturase 0.014 15.8 0.1 0.021 15.2 0.1 1.3 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repe 0.2 12.2 0.1 0.45 11.0 0.1 1.6 1 Bromo_TP Bromodomain associated Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.0 4.1e-07 0.00088 54 86 .. 59 91 .. 18 92 .. 0.91 2 ! 69.1 0.4 2.2e-22 4.6e-19 7 88 .] 122 199 .. 116 199 .. 0.94 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 4.1e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAv 86 ++ +l+ + ++A +++haKR+T+t+ D+ A+ FUN_000109-T1 59 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 788*************************98875 PP == domain 2 score: 69.1 bits; conditional E-value: 2.2e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000109-T1 122 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 199 57788999999*****************....************************************************97 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 2e-06 0.0042 32 65 .] 58 91 .. 32 91 .. 0.84 2 ! 16.8 0.0 4.1e-06 0.0087 8 65 .] 140 197 .. 139 197 .. 0.95 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 2e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000109-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 5778*************************98876 PP == domain 2 score: 16.8 bits; conditional E-value: 4.1e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000109-T1 140 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 197 6799****88888.*****************************************9996 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.1 0.21 4.5e+02 27 82 .. 51 108 .. 26 132 .. 0.59 2 ! 32.6 0.0 3.5e-11 7.4e-08 10 91 .. 143 223 .. 138 224 .] 0.84 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.21 Histone_ABTB 27 vvkrlsallqraLvriareaqRLskllakctke..evksavklvlseslaesCikaav 82 + ++ +l++ L ++ r+a +++ ++ t + +v +a++ ++ + +C aa FUN_000109-T1 51 IYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTamDVVYALNSSSFRTASCKCRAAAK 108 4444455666666666666666666655544430044444443333444445555555 PP == domain 2 score: 32.6 bits; conditional E-value: 3.5e-11 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000109-T1 143 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 223 5555544333...788899999999999*************99998763378****************************9865 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.1 5.1e-08 0.00011 28 75 .. 44 91 .. 17 109 .. 0.79 2 ? 2.2 0.0 0.12 2.6e+02 29 74 .. 151 196 .. 139 209 .. 0.84 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 5.1e-08 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLl 75 +++s e +++ f+e v D +y++HA+RKt+ Dv+ l FUN_000109-T1 44 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 446666667777778899**************************9765 PP == domain 2 score: 2.2 bits; conditional E-value: 0.12 CENP-T_C 29 aklskealealeqasewffeqvseDLeayakHAgRKtidesDvllL 74 + +s +a+ +++ + fe+++ + +++ ++ ti ++++ + FUN_000109-T1 151 TGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTA 196 5688999999999999999*99999888888888888888877665 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 2.2e-07 0.00048 35 65 .. 61 91 .. 27 92 .. 0.78 2 ? -0.2 0.0 0.76 1.6e+03 38 66 .] 170 198 .. 151 198 .. 0.80 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 2.2e-07 TAF 35 yrlkeivqeaakfmrhskRrkLtvaDvdsAL 65 l +++++a+ +++h+kR++ t+ Dv +AL FUN_000109-T1 61 VFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 55889**********************9998 PP == domain 2 score: -0.2 bits; conditional E-value: 0.76 TAF 38 keivqeaakfmrhskRrkLtvaDvdsALr 66 +i+ e+++ k +++++ ++ A+r FUN_000109-T1 170 ERIAVESSRLSLYNKKATISSREIQTAIR 198 56778888888888999999999999998 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 5.7e-06 0.012 38 70 .. 62 94 .. 34 102 .. 0.86 2 ? 3.4 0.0 0.052 1.1e+02 39 70 .. 169 200 .. 141 213 .. 0.79 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 5.7e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++s FUN_000109-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALNSS 94 6789*************************9875 PP == domain 2 score: 3.4 bits; conditional E-value: 0.052 TFIID-31kDa 39 ttevledAkvysehakkkkidlddvrlAiqsr 70 + +++ +s ++kk++i+ ++++Ai FUN_000109-T1 169 FERIAVESSRLSLYNKKATISSREIQTAIRLL 200 455667899999999**************875 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 5.7e-06 0.012 42 67 .. 63 88 .. 41 94 .. 0.88 2 ? -1.1 0.0 1.8 3.7e+03 26 49 .. 153 179 .. 137 196 .. 0.50 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 5.7e-06 CENP-S 42 lenlakDLeaFAkHAkRstittdDvl 67 len+ +D ++ +HAkR+t+t+ Dv+ FUN_000109-T1 63 LENVIRDAVTYTEHAKRKTVTAMDVV 88 789999*******************7 PP == domain 2 score: -1.1 bits; conditional E-value: 1.8 CENP-S 26 vtpqfi...aaltelvykqlenlakDL 49 ++++++ ++ ++ ++++++ ++ L FUN_000109-T1 153 ISSKAMgimNSFVNDIFERIAVESSRL 179 444444001333333344444333334 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.018 39 33 62 .. 62 91 .. 57 94 .. 0.90 2 ! 10.3 0.0 0.0005 1.1 7 60 .. 142 195 .. 139 199 .. 0.93 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.018 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhl 62 F e+v+ a+ h k +++ + D+ + l FUN_000109-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 99***********************98777 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0005 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000109-T1 142 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 195 5789************************************************95 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0028 5.9 32 65 .] 64 97 .. 62 97 .. 0.91 2 ! 6.1 0.0 0.0078 17 33 60 .. 171 198 .. 164 199 .. 0.88 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0028 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAleekeyR 65 ++++r A ++ +++++++v+a +V Al+ +R FUN_000109-T1 64 ENVIRDAVTYTEHAKRKTVTAMDVVYALNSSSFR 97 789999**********************988777 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0078 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000109-T1 171 RIAVESSRLSLYNKKATISSREIQTAIR 198 4678**********************96 PP >> Intron_maturas2 Type II intron maturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.2 9.5e-06 0.02 32 109 .. 44 121 .. 27 152 .. 0.83 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 9.5e-06 Intron_maturas2 32 PrsvlrwidledrdIllry.kaiirgllnYYsfasnkkrlrerikyilrkscvkTLArKlklktvrkvikkfGkklsdl 109 +++ +i++e+r +l+ + + +ir + Y a++k+ + + y l+ s +T K + +k k+ Gk s FUN_000109-T1 44 VKRISGLIYEETRGVLKVFlENVIRDAVTYTEHAKRKTVTAMDVVYALNSSSFRTASCKCRA-AAKKGEKRVGKAKSGT 121 5678899**********99457*******************9*******************9.9999999999544433 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 1e-05 0.021 25 117 .. 105 200 .. 83 204 .. 0.70 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1e-05 ARM_TT21 25 eAlktLktAlklpg.kkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 A+k ++ + ++ + +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000109-T1 105 AAAKKGEKRVGKAKsGTAETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 200 444333333332221222333344445567778899999*******************98765266656788**********************98 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.00021 0.45 34 70 .. 57 93 .. 52 100 .. 0.87 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00021 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L+ FUN_000109-T1 57 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALNS 93 56778999999*********************99975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 853 (0.0333921); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2234.11 // Query: FUN_000110-T1 [L=164] Description: FUN_000110 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000110-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000110-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000110-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1640.31 // Query: FUN_000111-T1 [L=129] Description: FUN_000111 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000111-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000111-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000111-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000111-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.38 # Mc/sec: 1350.71 // Query: FUN_000112-T1 [L=139] Description: FUN_000112 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000112-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000112-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000112-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000112-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000112-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000112-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000112-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000112-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000112-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1378.96 // Query: FUN_000113-T1 [L=129] Description: FUN_000113 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000113-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000113-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000113-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000113-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1306.49 // Query: FUN_000114-T1 [L=238] Description: FUN_000114 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-54 181.7 0.1 4.2e-38 130.1 0.2 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 1.6e-20 73.0 1.7 3.6e-20 71.9 1.7 1.7 1 Histone_H2A_C C-terminus of histone H2A 7.8e-10 39.4 0.0 0.00011 22.9 0.0 2.4 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 6.2e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 CENP-T_C Centromere kinetochore component CENP-T his 0.00089 20.5 0.9 0.0014 19.9 0.9 1.3 1 PAF PCNA-associated factor histone like domain 0.0015 19.3 0.1 0.0045 17.9 0.0 1.7 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.033 14.7 0.1 0.28 11.7 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD s 0.065 13.6 0.0 0.14 12.6 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.1 0.2 1.3e-41 4.2e-38 1 88 [] 44 131 .. 44 131 .. 0.99 2 ! 49.5 0.0 1.8e-16 5.8e-13 21 87 .. 136 201 .. 132 202 .. 0.95 Alignments for each domain: == domain 1 score: 130.1 bits; conditional E-value: 1.3e-41 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000114-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 131 689************************************************************************************7 PP == domain 2 score: 49.5 bits; conditional E-value: 1.8e-16 Histone 21 qklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000114-T1 136 LQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 201 689**********8.89999**********************************************9 PP >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.9 1.7 1.1e-23 3.6e-20 1 34 [. 204 237 .. 204 238 .] 0.97 Alignments for each domain: == domain 1 score: 71.9 bits; conditional E-value: 1.1e-23 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000114-T1 204 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 237 9*******************************96 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 1.7e-05 0.054 2 64 .. 65 128 .. 64 128 .. 0.93 2 ! 22.9 0.0 3.4e-08 0.00011 2 65 .] 137 200 .. 136 200 .. 0.98 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.7e-05 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000114-T1 65 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 128 7888888887888889999******************************************998 PP == domain 2 score: 22.9 bits; conditional E-value: 3.4e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000114-T1 137 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 200 69************************************************************98 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.3e-08 0.00017 11 77 .. 70 130 .. 59 143 .. 0.83 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.3e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000114-T1 70 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 130 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.9 4.3e-07 0.0014 1 62 [. 1 58 [. 1 80 [. 0.90 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 4.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000114-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 58 99***998...9***************999999999988899999998.6999999999996 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-06 0.0045 14 71 .. 71 130 .. 65 134 .. 0.83 2 ? -2.0 0.0 2.1 6.7e+03 53 76 .] 183 206 .. 160 206 .. 0.71 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-06 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000114-T1 71 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 444433311666789999*************************************99876 PP == domain 2 score: -2.0 bits; conditional E-value: 2.1 CENP-S 53 AkHAkRstittdDvlLlaRrnesL 76 A+ k+s i + + L +R++e+L FUN_000114-T1 183 ARDNKKSRIIPRHLQLAVRNDEEL 206 455567777777788888887765 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 8.8e-05 0.28 23 70 .. 85 132 .. 69 148 .. 0.87 2 ? 0.3 0.0 0.31 9.8e+02 40 69 .. 173 202 .. 160 211 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.8e-05 TFIID-31kDa 23 yeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA r FUN_000114-T1 85 FQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIR 132 78889999***********************************96655 PP == domain 2 score: 0.3 bits; conditional E-value: 0.31 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000114-T1 173 AEILELAGNAARDNKKSRIIPRHLQLAVRN 202 689999999999999999999999999975 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 4.3e-05 0.14 35 77 .] 51 93 .. 49 93 .. 0.92 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.3e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000114-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66677889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2341.06 // Query: FUN_000115-T1 [L=164] Description: FUN_000115 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000115-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000115-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000115-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1691.37 // Query: FUN_000116-T1 [L=129] Description: FUN_000116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000116-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000116-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000116-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000116-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1322.57 // Query: FUN_000117-T1 [L=164] Description: FUN_000117 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000117-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000117-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000117-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1637.19 // Query: FUN_000118-T1 [L=129] Description: FUN_000118 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000118-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000118-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000118-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000118-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.36s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 1333.79 // Query: FUN_000119-T1 [L=164] Description: FUN_000119 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000119-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000119-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000119-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.42s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 1603.79 // Query: FUN_000120-T1 [L=129] Description: FUN_000120 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000120-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000120-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000120-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000120-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1319.89 // Query: FUN_000121-T1 [L=139] Description: FUN_000121 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000121-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000121-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000121-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000121-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000121-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000121-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000121-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000121-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000121-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1369.21 // Query: FUN_000122-T1 [L=215] Description: FUN_000122 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-25 89.4 3.4 4.3e-19 69.2 0.4 2.3 2 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-09 37.1 0.2 9.6e-08 32.6 0.1 2.4 2 CENP-T_C Centromere kinetochore component CENP-T histon 4.8e-09 36.8 0.7 0.004 17.9 0.1 2.6 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.3e-08 34.3 0.1 6.8e-08 32.7 0.0 1.7 2 Histone_ABTB Histone domain in ABTB family protein 2.9e-05 24.6 0.3 0.00016 22.3 0.1 2.2 2 TAF TATA box binding protein associated factor (TA 0.00023 22.1 0.0 1 10.4 0.0 2.4 2 TFIID_20kDa Transcription initiation factor TFIID subunit 0.00038 21.0 0.0 0.018 15.6 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD subu 0.00046 21.0 0.0 0.002 19.0 0.0 2.0 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.02 15.4 0.1 12 6.5 0.0 2.6 2 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain 0.025 15.0 0.1 0.037 14.5 0.1 1.3 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.068 13.7 0.0 0.17 12.4 0.0 1.6 1 Bromo_TP Bromodomain associated Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.2 1.7e-07 0.0004 54 87 .. 59 92 .. 18 93 .. 0.91 2 ! 69.2 0.4 1.8e-22 4.3e-19 7 88 .] 113 190 .. 107 190 .. 0.94 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 1.7e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_000122-T1 59 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 92 788**************************99986 PP == domain 2 score: 69.2 bits; conditional E-value: 1.8e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000122-T1 113 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 190 57788999999*****************....************************************************97 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.6 0.1 4.1e-11 9.6e-08 28 85 .. 44 101 .. 17 109 .. 0.81 2 ? 2.3 0.0 0.1 2.4e+02 29 74 .. 142 187 .. 130 200 .. 0.84 Alignments for each domain: == domain 1 score: 32.6 bits; conditional E-value: 4.1e-11 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrkitkkt 85 +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq+ kk+ FUN_000122-T1 44 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGPAAKKG 101 456666667777778899*********************************9877766 PP == domain 2 score: 2.3 bits; conditional E-value: 0.1 CENP-T_C 29 aklskealealeqasewffeqvseDLeayakHAgRKtidesDvllL 74 + +s +a+ +++ + fe+++ + +++ ++ ti ++++ + FUN_000122-T1 142 TGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTA 187 568999999999999999**99999888888888888888877665 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.1 1.7e-06 0.004 32 65 .] 58 91 .. 32 91 .. 0.84 2 ! 16.9 0.0 3.5e-06 0.0081 8 65 .] 131 188 .. 130 188 .. 0.95 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.7e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000122-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 5778*************************98876 PP == domain 2 score: 16.9 bits; conditional E-value: 3.5e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000122-T1 131 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 188 6799****88888.*****************************************9996 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 0.93 2.2e+03 33 55 .. 57 79 .. 24 101 .. 0.54 2 ! 32.7 0.0 2.9e-11 6.8e-08 10 91 .. 134 214 .. 129 215 .] 0.84 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.93 Histone_ABTB 33 allqraLvriareaqRLskllak 55 +l++ L ++ r+a +++ ++ FUN_000122-T1 57 GVLKVFLENVIRDAVTYTEHAKR 79 33444444444444444433333 PP == domain 2 score: 32.7 bits; conditional E-value: 2.9e-11 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000122-T1 134 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 214 5555544333...788899999999999*************99998763378****************************9865 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.1 6.8e-08 0.00016 35 66 .] 61 92 .. 27 92 .. 0.78 2 ? -0.1 0.0 0.65 1.5e+03 38 66 .] 161 189 .. 142 189 .. 0.80 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 6.8e-08 TAF 35 yrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_000122-T1 61 VFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 92 55889*************************97 PP == domain 2 score: -0.1 bits; conditional E-value: 0.65 TAF 38 keivqeaakfmrhskRrkLtvaDvdsALr 66 +i+ e+++ k +++++ ++ A+r FUN_000122-T1 161 ERIAVESSRLSLYNKKATISSREIQTAIR 189 56778888888888999999999999998 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.2 0.0 0.0011 2.5 33 65 .. 62 94 .. 57 95 .. 0.94 2 ! 10.4 0.0 0.00043 1 7 60 .. 133 186 .. 130 190 .. 0.93 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0011 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhlern 65 F e+v+ a+ h k +++ + D+ + l+r+ FUN_000122-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 99*****************************96 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00043 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000122-T1 133 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 186 5789************************************************95 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 8e-06 0.018 38 70 .. 62 94 .. 34 105 .. 0.85 2 ? 3.5 0.0 0.045 1e+02 39 70 .. 160 191 .. 132 204 .. 0.79 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 8e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++ + FUN_000122-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 6789***********************999765 PP == domain 2 score: 3.5 bits; conditional E-value: 0.045 TFIID-31kDa 39 ttevledAkvysehakkkkidlddvrlAiqsr 70 + +++ +s ++kk++i+ ++++Ai FUN_000122-T1 160 FERIAVESSRLSLYNKKATISSREIQTAIRLL 191 45566789999999***************875 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.0 8.7e-07 0.002 42 73 .. 63 94 .. 36 96 .. 0.89 2 ? -1.0 0.0 1.5 3.5e+03 26 49 .. 144 170 .. 128 187 .. 0.50 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 8.7e-07 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_000122-T1 63 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 789999*******************9988875 PP == domain 2 score: -1.0 bits; conditional E-value: 1.5 CENP-S 26 vtpqfi...aaltelvykqlenlakDL 49 ++++++ ++ ++ ++++++ ++ L FUN_000122-T1 144 ISSKAMgimNSFVNDIFERIAVESSRL 170 444444001333333344444433334 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.0052 12 32 61 .. 64 93 .. 62 95 .. 0.90 2 ? 6.2 0.0 0.0067 16 33 60 .. 162 189 .. 155 190 .. 0.88 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0052 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAlee 61 ++++r A ++ +++++++v+a +V Al+ FUN_000122-T1 64 ENVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 789999*******************99976 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0067 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000122-T1 162 RIAVESSRLSLYNKKATISSREIQTAIR 189 4678**********************96 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.1 1.6e-05 0.037 42 117 .. 114 191 .. 64 195 .. 0.76 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.6e-05 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000122-T1 114 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 191 223333344556677889999*******************98765266656788**********************98 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 7.4e-05 0.17 34 70 .. 57 93 .. 52 97 .. 0.90 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7.4e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_000122-T1 57 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 56778999999************************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (215 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 725 (0.0283813); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.42 # Mc/sec: 2084.70 // Query: FUN_000123-T1 [L=164] Description: FUN_000123 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000123-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000123-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000123-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1610.57 // Query: FUN_000124-T1 [L=129] Description: FUN_000124 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000124-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000124-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000124-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000124-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1267.05 // Query: FUN_000125-T1 [L=164] Description: FUN_000125 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000125-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000125-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000125-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1646.87 // Query: FUN_000126-T1 [L=129] Description: FUN_000126 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000126-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000126-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000126-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000126-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.35s 00:00:00.62 Elapsed: 00:00:00.38 # Mc/sec: 1354.18 // Query: FUN_000127-T1 [L=164] Description: FUN_000127 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000127-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000127-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000127-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1599.69 // Query: FUN_000128-T1 [L=129] Description: FUN_000128 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000128-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000128-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000128-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000128-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1278.68 // Query: FUN_000129-T1 [L=164] Description: FUN_000129 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000129-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000129-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000129-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1624.26 // Query: FUN_000130-T1 [L=129] Description: FUN_000130 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000130-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000130-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000130-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000130-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1293.99 // Query: FUN_000131-T1 [L=139] Description: FUN_000131 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000131-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000131-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000131-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000131-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000131-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000131-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000131-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000131-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000131-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1432.72 // Query: FUN_000132-T1 [L=129] Description: FUN_000132 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000132-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000132-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000132-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000132-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1297.33 // Query: FUN_000133-T1 [L=103] Description: FUN_000133 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-08 34.4 0.1 4.3e-08 33.7 0.1 1.4 1 CENP-T_C Centromere kinetochore component CENP-T histon 2.5e-05 24.8 0.2 3.7e-05 24.3 0.2 1.4 1 TAF TATA box binding protein associated factor (TA 6.4e-05 23.7 0.2 8.6e-05 23.3 0.2 1.4 1 Histone Core histone H2A/H2B/H3/H4 domain 0.0003 21.6 0.1 0.00041 21.2 0.1 1.4 1 CENP-S CENP-S protein 0.00048 20.8 0.3 0.0009 20.0 0.2 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 0.003 18.1 0.0 0.0034 18.0 0.0 1.1 1 TFIID-31kDa Transcription initiation factor IID, 31kD subu ------ inclusion threshold ------ 0.026 15.0 0.0 0.043 14.3 0.0 1.3 1 Bromo_TP Bromodomain associated 0.26 11.5 0.2 0.32 11.3 0.2 1.0 1 UPF0137 Uncharacterised protein family (UPF0137) Domain annotation for each model (and alignments): >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.7 0.1 1.3e-11 4.3e-08 28 80 .. 44 96 .. 21 98 .. 0.81 Alignments for each domain: == domain 1 score: 33.7 bits; conditional E-value: 1.3e-11 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq++ FUN_000133-T1 44 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR 96 456777777777888999*********************************75 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.2 1.1e-08 3.7e-05 33 66 .] 59 92 .. 27 92 .. 0.75 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 1.1e-08 TAF 33 veyrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 ++ l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_000133-T1 59 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 92 5566889*************************98 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.2 2.7e-08 8.6e-05 53 87 .. 58 92 .. 16 93 .. 0.89 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 2.7e-08 Histone 53 avedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 +++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_000133-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 92 5789**************************99986 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.1 1.3e-07 0.00041 42 73 .. 63 94 .. 28 97 .. 0.88 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 1.3e-07 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_000133-T1 63 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 789999*******************9998885 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.2 2.8e-07 0.0009 32 65 .] 58 91 .. 30 91 .. 0.82 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 2.8e-07 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000133-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 6788*************************98876 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 1.1e-06 0.0034 38 70 .. 62 94 .. 32 100 .. 0.82 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 1.1e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++ + FUN_000133-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 6789************************99876 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 1.4e-05 0.043 34 70 .. 57 93 .. 51 96 .. 0.90 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.4e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_000133-T1 57 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 67778999999************************97 PP >> UPF0137 Uncharacterised protein family (UPF0137) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.2 0.0001 0.32 141 212 .. 23 94 .. 18 99 .. 0.92 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0001 UPF0137 141 lkaeveslPrqavYtLasRegslekkeeiienynGetktelleiirktfPlldtdrRqknlsekllellakl 212 l+ +++ + + a+ La R g + i e+ +G k l ++ir + +++ +R++ + ++ l++ FUN_000133-T1 23 LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 7889999**************9999999********************************999999999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 670 (0.0262282); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1020.49 // Query: FUN_000134-T1 [L=164] Description: FUN_000134 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000134-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000134-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000134-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1622.60 // Query: FUN_000135-T1 [L=181] Description: FUN_000135 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-19 70.5 0.4 2.9e-19 69.7 0.4 1.4 1 Histone Core histone H2A/H2B/H3/H4 domain 2.4e-08 34.2 0.0 4.6e-08 33.3 0.0 1.5 1 Histone_ABTB Histone domain in ABTB family protein 0.0019 18.9 0.0 0.0058 17.4 0.0 1.8 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) ------ inclusion threshold ------ 0.015 15.8 0.1 0.02 15.3 0.1 1.1 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repe 0.099 13.1 0.1 0.19 12.2 0.1 1.4 1 RNase_P-MRP_p29 Ribonuclease P/MRP, subunit p29 Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.7 0.4 5.6e-23 2.9e-19 7 88 .] 79 156 .. 73 156 .. 0.94 Alignments for each domain: == domain 1 score: 69.7 bits; conditional E-value: 5.6e-23 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000135-T1 79 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 156 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.0 9e-12 4.6e-08 10 91 .. 100 180 .. 95 181 .] 0.84 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 9e-12 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_000135-T1 100 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 180 5555544333...788899999999999*************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 1.1e-06 0.0058 8 65 .] 97 154 .. 96 154 .. 0.95 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 1.1e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000135-T1 97 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 154 679*****88888.*****************************************9996 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.1 3.9e-06 0.02 41 117 .. 79 157 .. 51 161 .. 0.73 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.9e-06 ARM_TT21 41 kskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000135-T1 79 AETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 157 2222333345556777889999*******************98765266656788**********************98 PP >> RNase_P-MRP_p29 Ribonuclease P/MRP, subunit p29 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 3.7e-05 0.19 25 55 .. 46 76 .. 37 95 .. 0.91 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.7e-05 RNase_P-MRP_p29 25 GikGivvdEtkntlkivtkenkvktipKegs 55 i+G++ +Et+ +lk++ ++ k++ K++s FUN_000135-T1 46 RISGLIYEETRGVLKVAAAKKGEKRVGKAKS 76 689************************9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 682 (0.026698); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1820.30 // Query: FUN_000136-T1 [L=164] Description: FUN_000136 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000136-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000136-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000136-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1614.34 // Query: FUN_000137-T1 [L=125] Description: FUN_000137 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-21 74.2 1.7 1.2e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.2e-15 58.1 0.0 1.6e-15 57.7 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 1.9e-05 25.3 0.0 2.7e-05 24.8 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.3e-05 24.5 0.0 4.1e-05 23.7 0.0 1.4 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 1.9e-24 1.2e-20 1 34 [. 91 124 .. 91 125 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 1.9e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000137-T1 91 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 124 9*******************************97 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.7 0.0 2.5e-19 1.6e-15 8 87 .. 10 88 .. 5 89 .. 0.94 Alignments for each domain: == domain 1 score: 57.7 bits; conditional E-value: 2.5e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000137-T1 10 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 88 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 4.2e-09 2.7e-05 2 65 .] 24 87 .. 23 87 .. 0.98 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 4.2e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000137-T1 24 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 87 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.5e-09 4.1e-05 94 136 .] 11 53 .. 6 53 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.5e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000137-T1 11 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 53 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (125 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 499 (0.0195342); expected 510.9 (0.02) Passed bias filter: 421 (0.0164807); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1240.49 // Query: FUN_000138-T1 [L=139] Description: FUN_000138 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000138-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000138-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000138-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000138-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000138-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000138-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000138-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000138-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000138-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1433.80 // Query: FUN_000139-T1 [L=129] Description: FUN_000139 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000139-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000139-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000139-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000139-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.35s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 1350.44 // Query: FUN_000140-T1 [L=238] Description: FUN_000140 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-54 181.7 0.1 4.2e-38 130.1 0.2 2.2 2 Histone Core histone H2A/H2B/H3/H4 domain 1.6e-20 73.0 1.7 3.6e-20 71.9 1.7 1.7 1 Histone_H2A_C C-terminus of histone H2A 7.8e-10 39.4 0.0 0.00011 22.9 0.0 2.4 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y 6.2e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 CENP-T_C Centromere kinetochore component CENP-T his 0.00089 20.5 0.9 0.0014 19.9 0.9 1.3 1 PAF PCNA-associated factor histone like domain 0.0015 19.3 0.1 0.0045 17.9 0.0 1.7 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.033 14.7 0.1 0.28 11.7 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD s 0.065 13.6 0.0 0.14 12.6 0.0 1.5 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.1 0.2 1.3e-41 4.2e-38 1 88 [] 44 131 .. 44 131 .. 0.99 2 ! 49.5 0.0 1.8e-16 5.8e-13 21 87 .. 136 201 .. 132 202 .. 0.95 Alignments for each domain: == domain 1 score: 130.1 bits; conditional E-value: 1.3e-41 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000140-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 131 689************************************************************************************7 PP == domain 2 score: 49.5 bits; conditional E-value: 1.8e-16 Histone 21 qklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000140-T1 136 LQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 201 689**********8.89999**********************************************9 PP >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.9 1.7 1.1e-23 3.6e-20 1 34 [. 204 237 .. 204 238 .] 0.97 Alignments for each domain: == domain 1 score: 71.9 bits; conditional E-value: 1.1e-23 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000140-T1 204 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 237 9*******************************96 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 1.7e-05 0.054 2 64 .. 65 128 .. 64 128 .. 0.93 2 ! 22.9 0.0 3.4e-08 0.00011 2 65 .] 137 200 .. 136 200 .. 0.98 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.7e-05 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000140-T1 65 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 128 7888888887888889999******************************************998 PP == domain 2 score: 22.9 bits; conditional E-value: 3.4e-08 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000140-T1 137 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 200 69************************************************************98 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.3e-08 0.00017 11 77 .. 70 130 .. 59 143 .. 0.83 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.3e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000140-T1 70 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 130 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.9 4.3e-07 0.0014 1 62 [. 1 58 [. 1 80 [. 0.90 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 4.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000140-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 58 99***998...9***************999999999988899999998.6999999999996 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-06 0.0045 14 71 .. 71 130 .. 65 134 .. 0.83 2 ? -2.0 0.0 2.1 6.7e+03 53 76 .] 183 206 .. 160 206 .. 0.71 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-06 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000140-T1 71 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130 444433311666789999*************************************99876 PP == domain 2 score: -2.0 bits; conditional E-value: 2.1 CENP-S 53 AkHAkRstittdDvlLlaRrnesL 76 A+ k+s i + + L +R++e+L FUN_000140-T1 183 ARDNKKSRIIPRHLQLAVRNDEEL 206 455567777777788888887765 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 8.8e-05 0.28 23 70 .. 85 132 .. 69 148 .. 0.87 2 ? 0.3 0.0 0.31 9.8e+02 40 69 .. 173 202 .. 160 211 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.8e-05 TFIID-31kDa 23 yeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA r FUN_000140-T1 85 FQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIR 132 78889999***********************************96655 PP == domain 2 score: 0.3 bits; conditional E-value: 0.31 TFIID-31kDa 40 tevledAkvysehakkkkidlddvrlAiqs 69 +e+le A ++++kk++i ++lA+ FUN_000140-T1 173 AEILELAGNAARDNKKSRIIPRHLQLAVRN 202 689999999999999999999999999975 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 4.3e-05 0.14 35 77 .] 51 93 .. 49 93 .. 0.92 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.3e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000140-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66677889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.28u 0.43s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2319.98 // Query: FUN_000141-T1 [L=229] Description: FUN_000141 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-25 90.2 2.2 4.9e-19 69.0 0.4 2.3 2 Histone Core histone H2A/H2B/H3/H4 domain 6.6e-09 36.4 0.6 0.0044 17.8 0.1 2.5 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 8.6e-09 36.0 0.1 2.6e-07 31.2 0.1 2.3 2 CENP-T_C Centromere kinetochore component CENP-T histon 3.5e-05 24.4 0.3 0.00018 22.1 0.1 2.1 2 TAF TATA box binding protein associated factor (TA 0.00028 21.8 0.0 1.1 10.3 0.0 2.3 2 TFIID_20kDa Transcription initiation factor TFIID subunit 0.00045 21.0 0.0 0.0021 18.9 0.0 2.0 2 CENP-S CENP-S protein 0.00047 20.7 0.1 0.018 15.6 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD subu 0.001 19.2 0.3 0.0025 17.9 0.1 1.7 2 Histone_ABTB Histone domain in ABTB family protein 0.002 18.6 0.1 0.0038 17.7 0.1 1.4 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat ------ inclusion threshold ------ 0.018 15.5 0.1 9.9 6.8 0.0 2.6 2 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain 0.082 13.4 0.0 0.19 12.2 0.0 1.5 1 Bromo_TP Bromodomain associated 0.11 13.0 0.1 0.16 12.4 0.1 1.3 1 YscO-like YscO-like protein Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.0 0.4 2.3e-22 4.9e-19 7 88 .] 23 100 .. 17 100 .. 0.94 2 ! 21.2 0.1 1.9e-07 0.00041 54 87 .. 185 218 .. 144 219 .. 0.91 Alignments for each domain: == domain 1 score: 69.0 bits; conditional E-value: 2.3e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000141-T1 23 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 57788999999*****************....************************************************97 PP == domain 2 score: 21.2 bits; conditional E-value: 1.9e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_000141-T1 185 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 218 788**************************99986 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 4.3e-06 0.0091 8 65 .] 41 98 .. 40 98 .. 0.95 2 ! 17.8 0.1 2.1e-06 0.0044 32 65 .] 184 217 .. 158 217 .. 0.84 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 4.3e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000141-T1 41 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 98 6799****88888.*****************************************9996 PP == domain 2 score: 17.8 bits; conditional E-value: 2.1e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000141-T1 184 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 217 5778*************************98876 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.098 2.1e+02 29 76 .. 52 99 .. 40 112 .. 0.84 2 ! 31.2 0.1 1.2e-10 2.6e-07 28 80 .. 170 222 .. 145 224 .. 0.81 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.098 CENP-T_C 29 aklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlk 76 + +s +a+ +++ + fe+++ + +++ ++ ti ++++ + ++ FUN_000141-T1 52 TGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIR 99 5689999***************99999999999999999888877655 PP == domain 2 score: 31.2 bits; conditional E-value: 1.2e-10 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq++ FUN_000141-T1 170 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR 222 446666667777778899*********************************75 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.79 1.7e+03 38 66 .] 71 99 .. 52 99 .. 0.80 2 ! 22.1 0.1 8.3e-08 0.00018 35 66 .] 187 218 .. 153 218 .. 0.78 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.79 TAF 38 keivqeaakfmrhskRrkLtvaDvdsALr 66 +i+ e+++ k +++++ ++ A+r FUN_000141-T1 71 ERIAVESSRLSLYNKKATISSREIQTAIR 99 56778888888888999999999999998 PP == domain 2 score: 22.1 bits; conditional E-value: 8.3e-08 TAF 35 yrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_000141-T1 187 VFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 218 55889*************************97 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.0 0.00053 1.1 7 60 .. 43 96 .. 40 100 .. 0.93 2 ! 9.0 0.0 0.0013 2.7 33 65 .. 188 220 .. 183 221 .. 0.94 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00053 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000141-T1 43 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 96 5789************************************************95 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0013 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhlern 65 F e+v+ a+ h k +++ + D+ + l+r+ FUN_000141-T1 188 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 220 99*****************************96 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 1.8 3.9e+03 26 49 .. 54 80 .. 38 97 .. 0.50 2 ! 18.9 0.0 9.8e-07 0.0021 42 73 .. 189 220 .. 167 223 .. 0.89 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.8 CENP-S 26 vtpqfi...aaltelvykqlenlakDL 49 ++++++ ++ ++ ++++++ ++ L FUN_000141-T1 54 ISSKAMgimNSFVNDIFERIAVESSRL 80 444444001333333344444333333 PP == domain 2 score: 18.9 bits; conditional E-value: 9.8e-07 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_000141-T1 189 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 220 789999*******************9998885 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.061 1.3e+02 39 69 .. 70 100 .. 42 113 .. 0.79 2 ! 15.6 0.0 8.5e-06 0.018 38 70 .. 188 220 .. 160 226 .. 0.85 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.061 TFIID-31kDa 39 ttevledAkvysehakkkkidlddvrlAiqs 69 + +++ +s ++kk++i+ ++++Ai FUN_000141-T1 70 FERIAVESSRLSLYNKKATISSREIQTAIRL 100 455667899999999*************986 PP == domain 2 score: 15.6 bits; conditional E-value: 8.5e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++ + FUN_000141-T1 188 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 220 6789************************99866 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.1 1.2e-06 0.0025 10 72 .. 44 105 .. 39 113 .. 0.80 2 ? -1.8 0.0 1.4 3e+03 33 53 .. 183 203 .. 151 218 .. 0.49 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.2e-06 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlses 72 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ + FUN_000141-T1 44 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPVT 105 5555544333...788899999999999*************99998763378*********9965 PP == domain 2 score: -1.8 bits; conditional E-value: 1.4 Histone_ABTB 33 allqraLvriareaqRLskll 53 +l++ L ++ r+a +++ FUN_000141-T1 183 GVLKVFLENVIRDAVTYTEHA 203 334444444444444444333 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.1 1.8e-06 0.0038 42 129 .. 24 113 .. 5 117 .. 0.79 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 1.8e-06 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelLkkikpdspyylq 129 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL ++ + +++++ FUN_000141-T1 24 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLLLPVTHSVNNHVR 113 233333445566778899999*******************98765266656788************************999998887765 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.008 17 33 60 .. 72 99 .. 65 100 .. 0.88 2 ? 6.8 0.0 0.0046 9.9 32 62 .. 190 220 .. 188 222 .. 0.90 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.008 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000141-T1 72 RIAVESSRLSLYNKKATISSREIQTAIR 99 4678**********************96 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0046 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAleek 62 ++++r A ++ +++++++v+a +V Al+ + FUN_000141-T1 190 ENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 220 789999*********************9876 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 9.2e-05 0.19 34 70 .. 183 219 .. 178 222 .. 0.90 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 9.2e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_000141-T1 183 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 219 56778999999************************97 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 7.6e-05 0.16 39 114 .. 24 101 .. 1 117 [. 0.72 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7.6e-05 YscO-like 39 akleaerdkvlkhkkaKlqq.lrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEeareel 114 + + r k+++ + + + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a l FUN_000141-T1 24 ETAKRRRGKRKESYAIYIYKvLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRLL 101 33344455566666666666455424599*****************************************99987666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (229 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 771 (0.030182); expected 510.9 (0.02) Passed bias filter: 633 (0.0247798); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2234.75 // Query: FUN_000142-T1 [L=221] Description: FUN_000142 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-18 64.8 1.3 1e-07 32.5 0.1 2.4 2 CENP-T_C Centromere kinetochore component CENP-T hist 5.6e-12 46.1 0.5 0.00017 22.2 0.1 2.5 2 TAF TATA box binding protein associated factor ( 1e-10 42.3 2.2 0.00041 21.1 0.2 2.5 2 Histone Core histone H2A/H2B/H3/H4 domain 5.2e-10 40.1 0.2 0.002 19.0 0.0 2.5 2 CENP-S CENP-S protein 6e-09 36.5 1.9 0.0041 17.8 0.1 2.7 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) 4.1e-08 33.8 0.1 0.011 16.3 0.0 2.1 2 TFIID-31kDa Transcription initiation factor IID, 31kD su 1.5e-06 28.6 0.4 0.043 14.3 0.1 2.3 2 Bromo_TP Bromodomain associated 0.0006 20.8 0.1 2.6 9.1 0.0 2.4 2 TFIID_20kDa Transcription initiation factor TFIID subuni 0.00083 19.8 0.2 2 8.9 0.0 2.2 2 TAFII28 hTAFII28-like protein conserved region 0.0018 18.6 1.2 1.4 9.1 0.1 2.0 2 UPF0137 Uncharacterised protein family (UPF0137) 0.0083 16.7 0.4 4.3 7.8 0.0 2.1 2 HIGH_NTase1_ass Cytidyltransferase-related C-terminal region 0.0088 16.2 0.0 2.6 8.1 0.0 2.1 2 PrkA PrkA serine protein kinase C-terminal domain ------ inclusion threshold ------ 0.016 15.8 0.1 9.4 6.9 0.0 2.5 2 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain 0.018 15.8 2.2 8.4 7.2 0.2 2.9 2 E3_binding e3 binding domain 0.025 15.4 0.0 7.2 7.5 0.0 2.8 2 CEP76_N CEP76 N-terminal domain 0.042 14.5 0.0 11 6.7 0.0 2.1 2 Csa5_I-A Type-I-A Cascade subunit Csa5 0.051 14.1 2.0 15 6.3 0.1 2.9 3 SAM_TNK SAM domain-like 0.06 13.9 0.2 16 6.1 0.0 2.3 2 TFIID-18kDa Transcription initiation factor IID, 18kD su 0.079 13.2 0.3 11 6.2 0.0 2.1 2 DUF8102 Domain of unknown function 0.091 13.0 0.0 18 5.6 0.0 2.2 2 dUTPase dUTPase 0.11 12.5 0.0 6 6.8 0.0 2.1 2 pAdhesive_6 Putative adhesive domain (group 6) 0.16 12.4 3.0 4.1 7.8 0.2 2.1 2 Flavi_DEAD Flavivirus DEAD domain 0.16 12.2 0.0 4.1 7.7 0.0 2.4 2 VapC50_C VapC50 C-terminal domain 0.24 11.2 0.2 12 5.7 0.0 2.1 2 TARBP1 TARBP1 domain Domain annotation for each model (and alignments): >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 0.1 9.5e-11 1e-07 28 82 .. 44 98 .. 17 106 .. 0.80 2 ! 31.3 0.1 2.3e-10 2.5e-07 28 80 .. 162 214 .. 136 216 .. 0.81 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 9.5e-11 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrkit 82 +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq++ + FUN_000142-T1 44 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGLTH 98 446666667777778899*********************************9765 PP == domain 2 score: 31.3 bits; conditional E-value: 2.3e-10 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq++ FUN_000142-T1 162 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR 214 446666667777778899*********************************75 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.1 1.6e-07 0.00017 35 66 .] 61 92 .. 27 92 .. 0.78 2 ! 22.2 0.1 1.6e-07 0.00017 35 66 .] 179 210 .. 145 210 .. 0.78 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 1.6e-07 TAF 35 yrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_000142-T1 61 VFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 92 55889*************************97 PP == domain 2 score: 22.2 bits; conditional E-value: 1.6e-07 TAF 35 yrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_000142-T1 179 VFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 210 55889*************************97 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.2 3.9e-07 0.00041 54 87 .. 59 92 .. 18 93 .. 0.91 2 ! 21.1 0.2 3.9e-07 0.00041 54 87 .. 177 210 .. 136 211 .. 0.91 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 3.9e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_000142-T1 59 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 92 788**************************99986 PP == domain 2 score: 21.1 bits; conditional E-value: 3.9e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_000142-T1 177 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 210 788**************************99986 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.1 2e-06 0.0021 42 73 .. 63 94 .. 41 115 .. 0.91 2 ! 19.0 0.0 1.8e-06 0.002 42 73 .. 181 212 .. 159 215 .. 0.89 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 2e-06 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_000142-T1 63 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 789999*******************9988875 PP == domain 2 score: 19.0 bits; conditional E-value: 1.8e-06 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_000142-T1 181 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 212 789999*******************9998885 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 3.9e-06 0.0041 32 65 .] 58 91 .. 32 91 .. 0.84 2 ! 17.8 0.1 3.9e-06 0.0041 32 65 .] 176 209 .. 150 209 .. 0.84 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 3.9e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000142-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 91 5778*************************98876 PP == domain 2 score: 17.8 bits; conditional E-value: 3.9e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000142-T1 176 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 209 5778*************************98876 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 1e-05 0.011 38 71 .. 62 95 .. 34 107 .. 0.81 2 ! 15.7 0.0 1.6e-05 0.017 38 70 .. 180 212 .. 152 218 .. 0.85 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 1e-05 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsrv 71 + +v++dA +y ehak+k++++ dv A++ + FUN_000142-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQG 95 6789*************************98765 PP == domain 2 score: 15.7 bits; conditional E-value: 1.6e-05 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++ + FUN_000142-T1 180 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 212 6789************************99866 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.1 4e-05 0.043 34 73 .. 57 96 .. 52 102 .. 0.88 2 ! 12.3 0.0 0.00017 0.18 34 70 .. 175 211 .. 170 214 .. 0.90 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 4e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqelgi 73 ++++ +++++ ++a + eha R ++t Dvv +L++ g+ FUN_000142-T1 57 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGL 96 56778999999*************************9887 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00017 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_000142-T1 175 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 211 56778999999************************97 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.1 0.0 0.0024 2.6 33 65 .. 62 94 .. 57 95 .. 0.94 2 ! 9.1 0.0 0.0024 2.6 33 65 .. 180 212 .. 175 213 .. 0.94 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0024 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhlern 65 F e+v+ a+ h k +++ + D+ + l+r+ FUN_000142-T1 62 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 99*****************************96 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0024 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhlern 65 F e+v+ a+ h k +++ + D+ + l+r+ FUN_000142-T1 180 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 212 99*****************************96 PP >> TAFII28 hTAFII28-like protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.0 0.0019 2 22 72 .. 30 80 .. 24 98 .. 0.85 2 ! 8.8 0.0 0.0021 2.2 22 72 .. 148 198 .. 142 211 .. 0.85 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0019 TAFII28 22 lnkaaikklvnsvlgqsvsqnvaivvaglaKvFvgeiveeAlevqeewges 72 + k ai++l+ + + +s + +g+ KvF +++ A++ e+ + + FUN_000142-T1 30 ITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRK 80 67889999999999999999999999****************999987655 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0021 TAFII28 22 lnkaaikklvnsvlgqsvsqnvaivvaglaKvFvgeiveeAlevqeewges 72 + k ai++l+ + + +s + +g+ KvF +++ A++ e+ + + FUN_000142-T1 148 ITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRK 198 67889999999999999999999999****************999987554 PP >> UPF0137 Uncharacterised protein family (UPF0137) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.1 0.1 0.0013 1.4 141 212 .. 23 94 .. 18 112 .. 0.87 2 ! 8.5 0.2 0.0021 2.3 141 212 .. 141 212 .. 136 217 .. 0.91 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0013 UPF0137 141 lkaeveslPrqavYtLasRegslekkeeiienynGetktelleiirktfPlldtdrRqknlsekllellakl 212 l+ +++ + + a+ La R g + i e+ +G k l ++ir + +++ +R++ + ++ l++ FUN_000142-T1 23 LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 7889999**************9999999********************************999999999763 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0021 UPF0137 141 lkaeveslPrqavYtLasRegslekkeeiienynGetktelleiirktfPlldtdrRqknlsekllellakl 212 l+ +++ + + a+ La R g + i e+ +G k l ++ir + +++ +R++ + ++ l++ FUN_000142-T1 141 LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 212 7889999**************9999999********************************999999999876 PP >> HIGH_NTase1_ass Cytidyltransferase-related C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.0 0.004 4.3 67 110 .. 23 66 .. 9 104 .. 0.84 2 ! 7.4 0.1 0.0054 5.7 68 110 .. 142 184 .. 128 207 .. 0.86 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.004 HIGH_NTase1_ass 67 fverieGvsGtkireavydgnlesvkkmlPeetidvlkeeleag 110 + + i+G++ ir+ g ++++ +++ eet vlk +le+ FUN_000142-T1 23 LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENV 66 45789*********************************999984 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0054 HIGH_NTase1_ass 68 verieGvsGtkireavydgnlesvkkmlPeetidvlkeeleag 110 + i+G++ ir+ g ++++ +++ eet vlk +le+ FUN_000142-T1 142 RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENV 184 5789*********************************999984 PP >> PrkA PrkA serine protein kinase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.0 0.0024 2.6 34 79 .. 55 100 .. 22 114 .. 0.80 2 ! 6.3 0.0 0.0088 9.4 34 72 .. 173 211 .. 141 216 .. 0.84 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0024 PrkA 34 msGvspRfvikalsealskseakkekcinpldvlnalekglkehes 79 +Gv f+ +++ +a++ +e++k+k+++++dv++al++ h++ FUN_000142-T1 55 TRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGLTHSV 100 57888889999*******9******************987666554 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0088 PrkA 34 msGvspRfvikalsealskseakkekcinpldvlnalek 72 +Gv f+ +++ +a++ +e++k+k+++++dv++al++ FUN_000142-T1 173 TRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 211 57888889999******99*****************987 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.012 13 32 61 .. 64 93 .. 62 95 .. 0.90 2 ? 6.9 0.0 0.0088 9.4 32 62 .. 182 212 .. 180 214 .. 0.90 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.012 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAlee 61 ++++r A ++ +++++++v+a +V Al+ FUN_000142-T1 64 ENVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 789999*******************99976 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0088 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAleek 62 ++++r A ++ +++++++v+a +V Al+ + FUN_000142-T1 182 ENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 212 789999*********************9876 PP >> E3_binding e3 binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.2 0.0079 8.4 4 16 .. 32 44 .. 30 49 .. 0.84 2 ? 7.2 0.2 0.0079 8.4 4 16 .. 150 162 .. 148 167 .. 0.84 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0079 E3_binding 4 sPaaRklArelGi 16 Pa R+lAr G+ FUN_000142-T1 32 KPAIRRLARRGGV 44 6********9999 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0079 E3_binding 4 sPaaRklArelGi 16 Pa R+lAr G+ FUN_000142-T1 150 KPAIRRLARRGGV 162 6********9999 PP >> CEP76_N CEP76 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.0068 7.2 21 53 .. 65 97 .. 52 106 .. 0.83 2 ? 5.0 0.0 0.041 43 21 51 .. 183 213 .. 170 213 .. 0.84 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0068 CEP76_N 21 dvlsetvreeegessrqlseedllkaLrerGiv 53 +v+ + v+ +e + +++ d+ aL+++G+ FUN_000142-T1 65 NVIRDAVTYTEHAKRKTVTAMDVVYALKRQGLT 97 56666666666667889**************85 PP == domain 2 score: 5.0 bits; conditional E-value: 0.041 CEP76_N 21 dvlsetvreeegessrqlseedllkaLrerG 51 +v+ + v+ +e + +++ d+ aL+++G FUN_000142-T1 183 NVIRDAVTYTEHAKRKTVTAMDVVYALKRQG 213 56666666666667889*************9 PP >> Csa5_I-A Type-I-A Cascade subunit Csa5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.0099 11 26 66 .. 46 86 .. 35 111 .. 0.79 2 ? 5.8 0.0 0.019 20 26 66 .. 164 204 .. 153 212 .. 0.85 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0099 Csa5_I-A 26 yidpliysldpkqikdvlsealreyvsylasaskrsvvlkd 66 i liy +k l + +r+ v+y+ a +++v+ d FUN_000142-T1 46 RISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMD 86 47889999999999*********************997554 PP == domain 2 score: 5.8 bits; conditional E-value: 0.019 Csa5_I-A 26 yidpliysldpkqikdvlsealreyvsylasaskrsvvlkd 66 i liy +k l + +r+ v+y+ a +++v+ d FUN_000142-T1 164 RISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMD 204 47889999999999********************9998765 PP >> SAM_TNK SAM domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.1 0.014 15 41 51 .. 29 39 .. 26 41 .. 0.89 2 ? -2.4 0.0 7.1 7.5e+03 40 53 .. 127 140 .. 124 143 .. 0.79 3 ? 6.3 0.1 0.014 15 41 51 .. 147 157 .. 144 159 .. 0.89 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.014 SAM_TNK 41 GmskpeiRRLr 51 G++kp+iRRL FUN_000142-T1 29 GITKPAIRRLA 39 99*******96 PP == domain 2 score: -2.4 bits; conditional E-value: 7.1 SAM_TNK 40 iGmskpeiRRLrka 53 G++k ++R rk FUN_000142-T1 127 FGLGKGGAKRHRKI 140 79999999998876 PP == domain 3 score: 6.3 bits; conditional E-value: 0.014 SAM_TNK 41 GmskpeiRRLr 51 G++kp+iRRL FUN_000142-T1 147 GITKPAIRRLA 157 99*******96 PP >> TFIID-18kDa Transcription initiation factor IID, 18kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.023 24 31 66 .. 58 93 .. 52 98 .. 0.90 2 ? 6.1 0.0 0.015 16 31 67 .. 176 212 .. 170 217 .. 0.88 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.023 TFIID-18kDa 31 lvrgyliellqqaakvaklrgsrkitlEDllfliRk 66 +++ +l +++ a+ +++ +++ +t D+++++++ FUN_000142-T1 58 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 56678999*************************987 PP == domain 2 score: 6.1 bits; conditional E-value: 0.015 TFIID-18kDa 31 lvrgyliellqqaakvaklrgsrkitlEDllfliRkD 67 +++ +l +++ a+ +++ +++ +t D+++++++ FUN_000142-T1 176 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 212 56678999*************************9986 PP >> DUF8102 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.01 11 82 122 .. 53 93 .. 42 110 .. 0.81 2 ? 5.1 0.0 0.022 23 82 120 .. 171 209 .. 160 215 .. 0.88 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.01 DUF8102 82 eetgldfesvleeairsaeeylaaadraatvsvdvtfevet 122 eet ++ le+ ir a +y + a+r+ ++ +dv + + FUN_000142-T1 53 EETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 5666778999*************************998776 PP == domain 2 score: 5.1 bits; conditional E-value: 0.022 DUF8102 82 eetgldfesvleeairsaeeylaaadraatvsvdvtfev 120 eet ++ le+ ir a +y + a+r+ ++ +dv + FUN_000142-T1 171 EETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 209 5666778999*************************9975 PP >> dUTPase dUTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.017 18 57 93 .. 39 76 .. 33 103 .. 0.86 2 ? 5.4 0.0 0.019 21 57 93 .. 157 194 .. 151 211 .. 0.86 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.017 dUTPase 57 aakglivvg.gvidsdyrGevkvvlfnstkkditikkg 93 a++g++ g+i + +rG +kv l n ++ +t+++ FUN_000142-T1 39 ARRGGVKRIsGLIYEETRGVLKVFLENVIRDAVTYTEH 76 56666666669********************9999876 PP == domain 2 score: 5.4 bits; conditional E-value: 0.019 dUTPase 57 aakglivvg.gvidsdyrGevkvvlfnstkkditikkg 93 a++g++ g+i + +rG +kv l n ++ +t+++ FUN_000142-T1 157 ARRGGVKRIsGLIYEETRGVLKVFLENVIRDAVTYTEH 194 56666666669********************9999875 PP >> pAdhesive_6 Putative adhesive domain (group 6) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.0056 6 99 159 .. 46 104 .. 12 108 .. 0.79 2 ? 3.8 0.0 0.047 51 99 142 .. 164 205 .. 128 216 .. 0.73 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0056 pAdhesive_6 99 tksGtlvYeiapgttsvaleltvkldltfllnnasrsfndaieVqssksenGaetiideek 159 sG l+Ye + g+ +v le ++ +t+ +++a+r+++ a++V + + +G ++ +++ + FUN_000142-T1 46 RISG-LIYEETRGVLKVFLENVIRDAVTY-TEHAKRKTVTAMDVVYALKRQGLTHSVNNHV 104 3333.99**********************.8888888888999988888899999888766 PP == domain 2 score: 3.8 bits; conditional E-value: 0.047 pAdhesive_6 99 tksGtlvYeiapgttsvaleltvkldltfllnnasrsfndaieV 142 sG l+Ye + g+ +v le ++ +t+ +++a+r+++ a++V FUN_000142-T1 164 RISG-LIYEETRGVLKVFLENVIRDAVTY-TEHAKRKTVTAMDV 205 3333.99**********************.55566655555555 PP >> Flavi_DEAD Flavivirus DEAD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.2 0.0039 4.1 15 91 .. 28 104 .. 16 113 .. 0.88 2 ? 5.3 0.2 0.024 26 15 75 .. 146 206 .. 134 213 .. 0.89 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0039 Flavi_DEAD 15 aGktrkvlpelvkeaierrlrtlvLaPtrvvlaemeealkglevryktsavkeektgreivdvmchatftkrllspv 91 +G t+ + +l ++ +r+ l+ tr vl+ e + v y+++a +++ t ++v ++ +t+ + ++v FUN_000142-T1 28 QGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGLTHSVNNHV 104 588999999999***************************************99999999999988888887766555 PP == domain 2 score: 5.3 bits; conditional E-value: 0.024 Flavi_DEAD 15 aGktrkvlpelvkeaierrlrtlvLaPtrvvlaemeealkglevryktsavkeektgreiv 75 +G t+ + +l ++ +r+ l+ tr vl+ e + v y+++a +++ t ++v FUN_000142-T1 146 QGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVV 206 588999999999*************************99999*******999888888877 PP >> VapC50_C VapC50 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.0038 4.1 27 51 .. 77 101 .. 66 102 .. 0.89 2 ? 1.7 0.0 0.27 2.9e+02 27 45 .. 195 213 .. 184 216 .. 0.88 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0038 VapC50_C 27 lknPPltveelLdrLerqGlpqfaa 51 k+ +t+ +++ +L+rqGl+ +++ FUN_000142-T1 77 AKRKTVTAMDVVYALKRQGLTHSVN 101 689999**************99885 PP == domain 2 score: 1.7 bits; conditional E-value: 0.27 VapC50_C 27 lknPPltveelLdrLerqG 45 k+ +t+ +++ +L+rqG FUN_000142-T1 195 AKRKTVTAMDVVYALKRQG 213 689999***********99 PP >> TARBP1 TARBP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.011 12 38 82 .. 61 104 .. 55 117 .. 0.77 2 ? 3.3 0.0 0.057 61 38 70 .. 179 211 .. 173 214 .. 0.91 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.011 TARBP1 38 etlkaalyealtadkdagkranmqlrveyLlkrivaltkeqelke 82 l++ + +a+t ++a +++ + v y lkr lt++ + + FUN_000142-T1 61 VFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ-GLTHSVNNHV 104 5688999**************************5.5666555443 PP == domain 2 score: 3.3 bits; conditional E-value: 0.057 TARBP1 38 etlkaalyealtadkdagkranmqlrveyLlkr 70 l++ + +a+t ++a +++ + v y lkr FUN_000142-T1 179 VFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 211 5688999*************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 435 (0.0170288); expected 510.9 (0.02) Passed bias filter: 365 (0.0142885); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 24 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2188.18 // Query: FUN_000143-T1 [L=164] Description: FUN_000143 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000143-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000143-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000143-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1602.02 // Query: FUN_000144-T1 [L=129] Description: FUN_000144 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000144-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000144-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000144-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000144-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1312.98 // Query: FUN_000145-T1 [L=139] Description: FUN_000145 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000145-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000145-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000145-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000145-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000145-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000145-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000145-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000145-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000145-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1406.00 // Query: FUN_000146-T1 [L=139] Description: FUN_000146 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-39 132.6 0.2 1.1e-38 132.0 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 3.7e-05 24.3 0.5 6.2e-05 23.6 0.1 1.6 2 CENP-T_C Centromere kinetochore component CENP-T his 0.00029 22.1 0.7 0.00034 21.9 0.7 1.1 1 PAF PCNA-associated factor histone like domain 0.00098 20.0 0.0 0.0015 19.3 0.0 1.3 1 CENP-S CENP-S protein 0.0072 17.1 0.0 0.017 15.9 0.0 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y ------ inclusion threshold ------ 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera 0.066 13.8 0.2 0.15 12.7 0.0 1.6 2 TFIID-31kDa Transcription initiation factor IID, 31kD s Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.0 0.2 3e-42 1.1e-38 1 88 [] 47 134 .. 47 134 .. 0.99 Alignments for each domain: == domain 1 score: 132.0 bits; conditional E-value: 3e-42 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++lv lfe++nl+a+haKRvT++pkDiqlA+r+ FUN_000146-T1 47 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI 134 689************************************************************************************7 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 2.6 9.6e+03 14 25 .. 22 33 .. 17 41 .. 0.64 2 ! 23.6 0.1 1.7e-08 6.2e-05 11 77 .. 73 133 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.6 CENP-T_C 14 krlakrfarasa 25 k+la+++ar+sa FUN_000146-T1 22 KQLATKAARKSA 33 455666655554 PP == domain 2 score: 23.6 bits; conditional E-value: 1.7e-08 CENP-T_C 11 avvkrlakrfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkR 77 +v+ +a++f + + + +a+ al++ase ++ + eD + a HA+R ti ++D+ L +R FUN_000146-T1 73 RLVREIAQDF-----KTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQ-LARR 133 3445555555.....47899****************************************86.4555 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.7 9.2e-08 0.00034 1 62 [. 4 61 .. 4 91 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 9.2e-08 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKg 62 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK FUN_000146-T1 4 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKS 61 99***998...9***************999999999988999999998.6999999999997 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 4.2e-07 0.0015 14 71 .. 74 133 .. 68 136 .. 0.83 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 4.2e-07 CENP-S 14 iveeeal..eekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaR 71 +v+e+a+ ++++ + ++++ al e + l l +D ++ A HAkR ti ++D+ L R FUN_000146-T1 74 LVREIAQdfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 444433312666789999*************************************99876 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-06 0.017 2 64 .. 68 131 .. 67 131 .. 0.93 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-06 CBFD_NFYB_HMF 2 eLPiarvkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklA 64 +LP r r + +d + + ++ ++A ++e+ e ++ + + ++ + ++kr Ti++++i+lA FUN_000146-T1 68 KLPFQRLVREIAQDfKTDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLA 131 789898888888888999*******************************************998 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.4e-05 0.051 35 77 .] 54 96 .. 51 96 .. 0.93 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.4e-05 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000146-T1 54 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 96 66678899999******************************98 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.6 5.8e+03 72 90 .. 12 30 .. 3 37 .. 0.64 2 ? 12.7 0.0 4e-05 0.15 22 68 .. 87 133 .. 72 138 .. 0.87 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.6 TFIID-31kDa 72 eksftepppkelLlelAre 90 +ks ++ p++ L++ A++ FUN_000146-T1 12 RKSTGGKAPRKQLATKAAR 30 4455566777777766654 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 TFIID-31kDa 22 eyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiq 68 ++ + vl L e Y + + ed ++++ hak+ +i +d++lA FUN_000146-T1 87 RFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 133 578889999***********************************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1397.35 // Query: FUN_000147-T1 [L=129] Description: FUN_000147 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000147-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000147-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000147-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000147-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1346.59 // Query: FUN_000148-T1 [L=129] Description: FUN_000148 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000148-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000148-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000148-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000148-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1305.80 // Query: FUN_000149-T1 [L=208] Description: FUN_000149 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-25 89.5 3.4 4e-19 69.3 0.4 2.3 2 Histone Core histone H2A/H2B/H3/H4 domain 4.7e-09 36.9 0.7 0.0038 18.0 0.1 2.5 2 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 8.9e-09 35.9 0.2 2.3e-07 31.4 0.1 2.3 2 CENP-T_C Centromere kinetochore component CENP-T histon 2.6e-05 24.8 0.3 0.00015 22.4 0.1 2.2 2 TAF TATA box binding protein associated factor (TA 0.00016 21.8 0.1 0.00049 20.2 0.0 1.7 2 Histone_ABTB Histone domain in ABTB family protein 0.0002 22.3 0.0 0.94 10.5 0.0 2.3 2 TFIID_20kDa Transcription initiation factor TFIID subunit 0.00028 21.4 0.0 0.015 15.8 0.0 2.2 2 TFIID-31kDa Transcription initiation factor IID, 31kD subu 0.00041 21.2 0.1 0.0017 19.2 0.0 2.0 2 CENP-S CENP-S protein ------ inclusion threshold ------ 0.013 16.0 0.1 8.6 7.0 0.0 2.6 2 LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain 0.025 15.0 0.1 0.049 14.1 0.1 1.4 1 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.068 13.7 0.0 0.17 12.4 0.0 1.6 1 Bromo_TP Bromodomain associated 0.12 12.9 0.1 0.18 12.3 0.1 1.3 1 YscO-like YscO-like protein Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.3 0.4 1.9e-22 4e-19 7 88 .] 23 100 .. 17 100 .. 0.94 2 ! 21.3 0.2 1.8e-07 0.00037 54 87 .. 164 197 .. 123 198 .. 0.91 Alignments for each domain: == domain 1 score: 69.3 bits; conditional E-value: 1.9e-22 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ ++++++++++++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_000149-T1 23 AETAKRRRGKRKESYAIYIYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 57788999999*****************....************************************************97 PP == domain 2 score: 21.3 bits; conditional E-value: 1.8e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_000149-T1 164 LKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 197 788**************************99986 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 3.6e-06 0.0076 8 65 .] 41 98 .. 40 98 .. 0.95 2 ! 18.0 0.1 1.8e-06 0.0038 32 65 .] 163 196 .. 137 196 .. 0.84 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 3.6e-06 CBFD_NFYB_HMF 8 vkrImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 + +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_000149-T1 41 IYKVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 98 6799****88888.*****************************************9996 PP == domain 2 score: 18.0 bits; conditional E-value: 1.8e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ +++++krKT++a ++ A+ FUN_000149-T1 163 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 196 5778*************************98876 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.12 2.5e+02 29 73 .. 52 96 .. 39 101 .. 0.84 2 ! 31.4 0.1 1.1e-10 2.3e-07 28 80 .. 149 201 .. 126 203 .. 0.81 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.12 CENP-T_C 29 aklskealealeqasewffeqvseDLeayakHAgRKtidesDvll 73 + +s +a+ +++ + fe+++ + +++ ++ ti ++++ + FUN_000149-T1 52 TGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 96 5689999***************99999999988888998887766 PP == domain 2 score: 31.4 bits; conditional E-value: 1.1e-10 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq++ FUN_000149-T1 149 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR 201 446666667777778899*********************************75 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.68 1.4e+03 38 66 .] 71 99 .. 52 99 .. 0.80 2 ! 22.4 0.1 7e-08 0.00015 34 66 .] 165 197 .. 132 197 .. 0.78 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.68 TAF 38 keivqeaakfmrhskRrkLtvaDvdsALr 66 +i+ e+++ k +++++ ++ A+r FUN_000149-T1 71 ERIAVESSRLSLYNKKATISSREIQTAIR 99 56778888888888999999999999998 PP == domain 2 score: 22.4 bits; conditional E-value: 7e-08 TAF 34 eyrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 + l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_000149-T1 165 KVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 197 555889*************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 2.3e-07 0.00049 10 74 .. 44 107 .. 39 111 .. 0.81 2 ? -1.5 0.0 1.2 2.5e+03 32 53 .. 161 182 .. 129 197 .. 0.49 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 2.3e-07 Histone_ABTB 10 vlqkgrlkeavelvsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlsesla 74 vl++++ + +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+++++ FUN_000149-T1 44 VLKQVHPDTG---ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPANMS 107 5555544333...788899999999999*************99998763378***********9987 PP == domain 2 score: -1.5 bits; conditional E-value: 1.2 Histone_ABTB 32 sallqraLvriareaqRLskll 53 +l++ L ++ r+a +++ FUN_000149-T1 161 RGVLKVFLENVIRDAVTYTEHA 182 3334444444444444444333 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00044 0.94 7 60 .. 43 96 .. 40 100 .. 0.93 2 ! 9.3 0.0 0.0011 2.3 33 65 .. 167 199 .. 162 200 .. 0.94 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00044 TFIID_20kDa 7 dLvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_000149-T1 43 KVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 96 5789************************************************95 PP == domain 2 score: 9.3 bits; conditional E-value: 0.0011 TFIID_20kDa 33 FvesvtkkacklakhRksdklevrDiqlhlern 65 F e+v+ a+ h k +++ + D+ + l+r+ FUN_000149-T1 167 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 199 99*****************************96 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.044 93 39 71 .. 70 102 .. 42 110 .. 0.78 2 ! 15.8 0.0 7.2e-06 0.015 38 70 .. 167 199 .. 139 205 .. 0.85 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.044 TFIID-31kDa 39 ttevledAkvysehakkkkidlddvrlAiqsrv 71 + +++ +s ++kk++i+ ++++Ai + FUN_000149-T1 70 FERIAVESSRLSLYNKKATISSREIQTAIRLLL 102 45666789999999***************8765 PP == domain 2 score: 15.8 bits; conditional E-value: 7.2e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y ehak+k++++ dv A++ + FUN_000149-T1 167 FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 199 6789************************99866 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 1.5 3.2e+03 26 49 .. 54 80 .. 37 97 .. 0.50 2 ! 19.2 0.0 7.9e-07 0.0017 42 73 .. 168 199 .. 139 202 .. 0.89 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.5 CENP-S 26 vtpqfi...aaltelvykqlenlakDL 49 ++++++ ++ ++ ++++++ ++ L FUN_000149-T1 54 ISSKAMgimNSFVNDIFERIAVESSRL 80 444444001333333444444434334 PP == domain 2 score: 19.2 bits; conditional E-value: 7.9e-07 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_000149-T1 168 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 199 789999*******************9998885 PP >> LonB_AAA-LID Archaeal LonB, AAA+ ATPase LID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.007 15 33 60 .. 72 99 .. 65 100 .. 0.88 2 ? 7.0 0.0 0.004 8.6 32 62 .. 169 199 .. 167 201 .. 0.90 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.007 LonB_AAA-LID 33 dllrEAdywAreegaevveaehVekAle 60 + +E++ ++ +++++++++++++A++ FUN_000149-T1 72 RIAVESSRLSLYNKKATISSREIQTAIR 99 4678**********************96 PP == domain 2 score: 7.0 bits; conditional E-value: 0.004 LonB_AAA-LID 32 adllrEAdywAreegaevveaehVekAleek 62 ++++r A ++ +++++++v+a +V Al+ + FUN_000149-T1 169 ENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 199 789999*********************9876 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.1 2.3e-05 0.049 42 117 .. 24 101 .. 5 106 .. 0.79 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.3e-05 ARM_TT21 42 skekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee.fkg.tpeevrillanaelalargdvdkAlelL 117 +++k+++ + +es + +y l +v+ +++ +++A+ ++++ +++ f+ e +r+ l n + +++ ++++A++lL FUN_000149-T1 24 ETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDiFERiAVESSRLSLYNKKATISSREIQTAIRLL 101 233333445566778899999*******************98765266656788**********************98 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 7.9e-05 0.17 34 70 .. 162 198 .. 157 201 .. 0.90 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7.9e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_000149-T1 162 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 198 56778999999************************97 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 8.3e-05 0.18 38 113 .. 23 100 .. 1 106 [. 0.71 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 8.3e-05 YscO-like 38 lakleaerdkvlkhkkaKlqq.lrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 + + r k+++ + + + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_000149-T1 23 AETAKRRRGKRKESYAIYIYKvLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 100 233344455566666666666455424599*****************************************9988655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 966 (0.0378156); expected 510.9 (0.02) Passed bias filter: 729 (0.0285379); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2105.08 // Query: FUN_000150-T1 [L=125] Description: FUN_000150 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (125 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 522 (0.0204345); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1260.31 // Query: FUN_000151-T1 [L=164] Description: FUN_000151 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000151-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000151-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000151-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1658.41 // Query: FUN_000152-T1 [L=129] Description: FUN_000152 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000152-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000152-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000152-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000152-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1290.08 // Query: FUN_000153-T1 [L=164] Description: FUN_000153 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000153-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000153-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000153-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1641.73 // Query: FUN_000154-T1 [L=129] Description: FUN_000154 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000154-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000154-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000154-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000154-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1311.43 // Query: FUN_000155-T1 [L=164] Description: FUN_000155 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000155-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000155-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000155-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1594.02 // Query: FUN_000156-T1 [L=129] Description: FUN_000156 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000156-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000156-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000156-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000156-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1300.88 // Query: FUN_000157-T1 [L=164] Description: FUN_000157 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000157-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000157-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000157-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.42s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1647.72 // Query: FUN_000158-T1 [L=129] Description: FUN_000158 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000158-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000158-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000158-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000158-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1295.15 // Query: FUN_000159-T1 [L=164] Description: FUN_000159 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000159-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000159-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000159-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1647.15 // Query: FUN_000160-T1 [L=129] Description: FUN_000160 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000160-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000160-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000160-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000160-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1285.13 // Query: FUN_000161-T1 [L=164] Description: FUN_000161 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000161-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000161-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000161-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1645.03 // Query: FUN_000162-T1 [L=129] Description: FUN_000162 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000162-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000162-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000162-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000162-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1314.99 // Query: FUN_000163-T1 [L=164] Description: FUN_000163 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000163-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000163-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000163-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1661.46 // Query: FUN_000164-T1 [L=129] Description: FUN_000164 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000164-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000164-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000164-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000164-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1297.58 // Query: FUN_000165-T1 [L=164] Description: FUN_000165 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000165-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000165-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000165-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1666.89 // Query: FUN_000166-T1 [L=129] Description: FUN_000166 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000166-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000166-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000166-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000166-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1309.77 // Query: FUN_000167-T1 [L=164] Description: FUN_000167 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000167-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000167-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000167-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1620.50 // Query: FUN_000168-T1 [L=129] Description: FUN_000168 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000168-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000168-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000168-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000168-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1278.47 // Query: FUN_000169-T1 [L=164] Description: FUN_000169 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000169-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000169-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000169-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1664.04 // Query: FUN_000170-T1 [L=129] Description: FUN_000170 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000170-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000170-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000170-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000170-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1284.54 // Query: FUN_000171-T1 [L=164] Description: FUN_000171 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000171-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000171-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000171-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1659.68 // Query: FUN_000172-T1 [L=129] Description: FUN_000172 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000172-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000172-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000172-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000172-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1291.56 // Query: FUN_000173-T1 [L=164] Description: FUN_000173 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000173-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000173-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000173-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1668.58 // Query: FUN_000174-T1 [L=129] Description: FUN_000174 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000174-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000174-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000174-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000174-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1290.95 // Query: FUN_000175-T1 [L=164] Description: FUN_000175 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000175-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000175-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000175-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1689.04 // Query: FUN_000176-T1 [L=129] Description: FUN_000176 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000176-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000176-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000176-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000176-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1295.58 // Query: FUN_000177-T1 [L=164] Description: FUN_000177 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000177-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000177-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000177-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1614.53 // Query: FUN_000178-T1 [L=129] Description: FUN_000178 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000178-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000178-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000178-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000178-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1297.36 // Query: FUN_000179-T1 [L=164] Description: FUN_000179 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-21 74.9 0.2 1.4e-20 73.9 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00092 20.4 3.1 0.0011 20.1 3.1 1.4 1 PAF PCNA-associated factor histone like domain ------ inclusion threshold ------ 0.042 14.2 0.0 0.072 13.5 0.0 1.3 1 YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransfera Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.9 0.2 1.6e-24 1.4e-20 1 60 [. 44 103 .. 44 107 .. 0.97 Alignments for each domain: == domain 1 score: 73.9 bits; conditional E-value: 1.6e-24 Histone 1 kgtkalkeirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllve 60 +gt+al+eir+yqkst+lli+klpf+R+vre+ +++k+dlr++++av alqea+e++l+e FUN_000179-T1 44 PGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLALQEASEAYLEE 103 689*******************************************************98 PP >> PAF PCNA-associated factor histone like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 3.1 1.3e-07 0.0011 1 67 [. 1 63 [. 1 152 [. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.3e-07 PAF 1 MvrTkAdvsaarkavaakAprkslgasssssstssssskkkkkkyaggNpvcprptPaWQKgIteFf 67 M+rTk ++ rk ++kAprk+l+++ + +s ++ kk + y +g v r++ QK + FUN_000179-T1 1 MARTKQTA---RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPG-TVALREIRRYQKSTELLI 63 99***998...9***************999999999988999999998.6999***99999866555 PP >> YebU_pre-PUA_dom Ribosomal RNA small subunit methyltransferase F, pre-PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.5e-06 0.072 35 77 .] 51 93 .. 49 93 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.5e-06 YebU_pre-PUA_dom 35 eiWLfpaaiepllgkvrfsRiGlklaetfkkGyrWqheaviaL 77 ei + +++e l+ k+ f+R+ +a fk r+q av+aL FUN_000179-T1 51 EIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVLAL 93 66678889999******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1625.29 // Query: FUN_000180-T1 [L=129] Description: FUN_000180 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-21 74.2 1.7 1.3e-20 73.3 1.7 1.5 1 Histone_H2A_C C-terminus of histone H2A 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 Histone Core histone H2A/H2B/H3/H4 domain 2.1e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.3 1 Histone_ABTB Histone domain in ABTB family protein Domain annotation for each model (and alignments): >> Histone_H2A_C C-terminus of histone H2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.3 1.7 2.1e-24 1.3e-20 1 34 [. 95 128 .. 95 129 .] 0.97 Alignments for each domain: == domain 1 score: 73.3 bits; conditional E-value: 2.1e-24 Histone_H2A_C 1 EELnkLLggVTIAqGGVLPnIhkaLLpkktkkkk 34 EELnkLL gVTIAqGGVLPnI+++LLpkkt+kk+ FUN_000180-T1 95 EELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQ 128 9*******************************96 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.6 0.0 2.8e-19 1.8e-15 8 87 .. 14 92 .. 9 93 .. 0.94 Alignments for each domain: == domain 1 score: 57.6 bits; conditional E-value: 2.8e-19 Histone 8 eirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 + +k+ +++++ + ++p+ R++r ++k + r+ a a+v++++++e+l e++e A ++a+++K++++ p+++qlAvr FUN_000180-T1 14 QGTKSKSRSSRAGLQFPVGRIHRLLRK-GNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVR 92 567899999*****************8.89999**********************************************9 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 4.5e-09 2.9e-05 2 65 .] 28 91 .. 27 91 .. 0.98 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.5e-09 CBFD_NFYB_HMF 2 eLPiarvkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++P +r+ r++++ + a+++ A++++a ++e e+++ A ++ k+ i + h++lAv FUN_000180-T1 28 QFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAV 91 69************************************************************98 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 6.4e-09 4.1e-05 94 136 .] 15 57 .. 6 57 .. 0.89 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 6.4e-09 Histone_ABTB 94 galkrsksaragLqlsvGrfyrwlvdtriskrvhdyaavylta 136 g+ +s+s+ragLq++vGr++r l + + ++rv a vy++a FUN_000180-T1 15 GTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAA 57 4457899**************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1308.04 // Query: FUN_000181-T1 [L=116] Description: FUN_000181 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0094 16.2 0.0 0.011 16.0 0.0 1.1 1 DUF8077 Domain of unknown function (DUF8077) Domain annotation for each model (and alignments): >> DUF8077 Domain of unknown function (DUF8077) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 4.2e-07 0.011 26 91 .. 31 96 .. 14 108 .. 0.88 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 4.2e-07 DUF8077 26 epfkealakvvnkyCrnataCrlkksvvfskeqvvlldgypkreeeavefrflvvlPheavplkkl 91 ++f ++ + +k +n t C lk++ + s ++vl ++++ + ++r + v+P++ ++l+++ FUN_000181-T1 31 KAFDSSCRQHRSKLYHNYTPCGLKERANASIAELVLSLSFSRDAADLRTLRLYNVFPPADRELARK 96 567788888888999******************************************998887554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 483 (0.0189078); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.40s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1185.41 // Query: FUN_000182-T1 [L=126] Description: FUN_000182 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-11 44.9 0.1 1.9e-11 44.5 0.1 1.2 1 zf-AD Zinc-finger associated domain (zf-AD) ------ inclusion threshold ------ 0.061 13.9 0.9 0.21 12.2 0.9 1.8 1 FYVE FYVE zinc finger Domain annotation for each model (and alignments): >> zf-AD Zinc-finger associated domain (zf-AD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.5 0.1 1.5e-15 1.9e-11 1 73 [. 22 97 .. 22 99 .. 0.95 Alignments for each domain: == domain 1 score: 44.5 bits; conditional E-value: 1.5e-15 zf-AD 1 vCRlCl...deeaellpifepsesektlaelleellgielspkdllpkkiCerCleklqefysFrkrclesqallq 73 vCR+C ++++l++f+++++++ ++++le+++g+++++ d+lp+ C++C+ k++++ F k++ es a+ + FUN_000182-T1 22 VCRTCNnnvILKSHPLDLFGDKAKDERIVADLEKMFGLKITRGDGLPSRTCRSCYVKISKIQAFVKMIFESKAQQE 97 7*****8888899*********9999*********************************************99865 PP >> FYVE FYVE zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.9 1.6e-05 0.21 20 66 .. 16 80 .. 8 81 .. 0.65 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.6e-05 FYVE 20 llrrrhHCrkCGkvfCskCs..................skkislleelkeekpvrvCdeCykkle 66 + +r+ Cr C + + k +k + l+ + ++ p r+C++Cy k++ FUN_000182-T1 16 FSSRKDVCRTCNNNVILKSHpldlfgdkakderivadlEKMFGLKITRGDGLPSRTCRSCYVKIS 80 557888999998877733333555555555444444444444444788899999*******9886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 975 (0.0381679); expected 510.9 (0.02) Passed bias filter: 709 (0.0277549); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1235.55 // Query: FUN_000183-T1 [L=180] Description: FUN_000183 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-06 29.0 0.2 1.9e-06 29.0 0.2 2.2 2 THAP THAP domain 0.0074 16.5 1.1 0.0074 16.5 1.1 1.5 2 DivIC Septum formation initiator ------ inclusion threshold ------ 0.015 15.0 0.7 0.016 14.9 0.7 1.1 1 Tmemb_cc2 Predicted transmembrane and coiled-coil 2 prot 0.051 14.1 4.0 0.075 13.6 4.0 1.3 1 UPF0242 Uncharacterised protein family (UPF0242) N-ter 0.057 14.0 1.3 0.064 13.9 0.4 1.5 2 TolA_bind_tri TolA binding protein trimerisation 0.13 11.8 0.5 0.18 11.3 0.5 1.2 1 Seadorna_VP6 Seadornavirus VP6 protein 0.14 12.9 0.3 0.23 12.3 0.3 1.3 1 TEDC1 Tubulin epsilon and delta complex protein 1 0.24 12.0 0.8 0.67 10.5 0.5 1.8 2 DUF2443 Protein of unknown function (DUF2443) Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 0.2 6e-10 1.9e-06 28 86 .] 4 57 .. 2 57 .. 0.89 2 ? -2.1 3.2 3 9.7e+03 24 60 .. 89 122 .. 58 154 .. 0.48 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 6e-10 THAP 28 errkkWlknikredlekkkk.kksrvCskHFeeelekeedeekrskkrrrLkpdavPtlf 86 ++r+kW k+++r d+ +++ ++ r+C +HF k +d++++ ++r +++ P++f FUN_000183-T1 4 ALRRKWRKFCRRADKGFETQeNP-RICAAHF-----KISDFKQSLNGRIDVRKGTSPSIF 57 5799*********9999999556.*******.....56788899999999********98 PP == domain 2 score: -2.1 bits; conditional E-value: 3 THAP 24 PkdkerrkkWlknikredlekkkkkksrvCskHFeee 60 P +++r+ + ++ e +++++ + +k F+++ FUN_000183-T1 89 PLKEARITQLKSAVAAEAVKHDHD---YCSHKDFHDK 122 444444444444444443332222...4455566444 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 5.6 1.8e+04 45 51 .. 93 99 .. 92 106 .. 0.45 2 ! 16.5 1.1 2.3e-06 0.0074 11 49 .. 119 157 .. 118 163 .. 0.92 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 5.6 DivIC 45 aeikdLk 51 a+i +Lk FUN_000183-T1 93 ARITQLK 99 4444443 PP == domain 2 score: 16.5 bits; conditional E-value: 2.3e-06 DivIC 11 fgkngllaykqlkqeiaeleaeiaklkaeneeLeaeikd 49 f++++ ++ ++l qe++ +++++++lk+en++L+a+++d FUN_000183-T1 119 FHDKSTQTNFDLPQELQGIKEDLQRLKEENDKLKAKLDD 157 5788999****************************9886 PP >> Tmemb_cc2 Predicted transmembrane and coiled-coil 2 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.7 5.1e-06 0.016 177 249 .. 87 158 .. 22 179 .. 0.57 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 5.1e-06 Tmemb_cc2 177 yksddevssssvesssadsnsnkeesaaenekeaesesqekleaileelqelkeeqaqleekleelkeqlkke 249 y+ e++ ++ +s++a ++ +++++ + +k + +s+++ + +elq +ke+ ++l+e+ ++lk++l+ + FUN_000183-T1 87 YQPLKEARITQLKSAVAAEAVKHDHDYCS-HKDFHDKSTQTNFDLPQELQGIKEDLQRLKEENDKLKAKLDDK 158 22222333333335555544444444443.3344444444444556777777777777777777777766543 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 4.0 2.3e-05 0.075 72 143 .. 90 169 .. 59 175 .. 0.72 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.3e-05 UPF0242 72 ekeallteed....aedlkilee......eleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfaefklesee 143 kea +t+++ ae +k ++ +++++ + +l +el+ +e l++lkee+++lk kl++ ++ + +l++ + FUN_000183-T1 90 LKEARITQLKsavaAEAVKHDHDycshkdFHDKSTQTNFDLPQELQGIKEDLQRLKEENDKLKAKLDD--KETLKRELFMGD 169 4555555555555544444444444333256677888899**************************99..555555555555 PP >> TolA_bind_tri TolA binding protein trimerisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 5.8 1.8e+04 4 11 .. 93 100 .. 92 105 .. 0.48 2 ? 13.9 0.4 2e-05 0.064 16 59 .. 123 166 .. 119 168 .. 0.90 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 5.8 TolA_bind_tri 4 dRlarLEr 11 +R+++L FUN_000183-T1 93 ARITQLKS 100 45555543 PP == domain 2 score: 13.9 bits; conditional E-value: 2e-05 TolA_bind_tri 16 rnqallelqqqleqLqqevaeLRGqiEelqyqleqlqeRqrdlY 59 ++q++++l q+l+ +++++++L+ ++++l+ +l++ + r+l+ FUN_000183-T1 123 STQTNFDLPQELQGIKEDLQRLKEENDKLKAKLDDKETLKRELF 166 579******************************99888888875 PP >> Seadorna_VP6 Seadornavirus VP6 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.5 5.7e-05 0.18 2 38 .. 125 159 .. 124 175 .. 0.81 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 5.7e-05 Seadorna_VP6 2 aEnqeLrdevvdlreenealkaennvLkrklaaLeee 38 + n++L +e+ ++e+ ++lk+en++Lk+kl ++e FUN_000183-T1 125 QTNFDLPQELQGIKEDLQRLKEENDKLKAKLD--DKE 159 6799999**********************986..444 PP >> TEDC1 Tubulin epsilon and delta complex protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.3 7.1e-05 0.23 86 148 .. 96 158 .. 88 166 .. 0.84 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 7.1e-05 TEDC1 86 aqqekakllhkihsatqgvsvdpslnhlsvletkllrdpeelkkllqllekensrLealleWk 148 +q + a +++ + + +s + +++ + ++ +l ++ + +k++lq+l++en++L+a l+ k FUN_000183-T1 96 TQLKSAVAAEAVKHDHDYCSHKDFHDKSTQTNFDLPQELQGIKEDLQRLKEENDKLKAKLDDK 158 555666677778888888999999999******************************999755 PP >> DUF2443 Protein of unknown function (DUF2443) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.3 4.2e+03 44 68 .. 79 104 .. 76 109 .. 0.67 2 ? 10.5 0.5 0.00021 0.67 41 77 .. 128 166 .. 118 167 .. 0.86 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.3 DUF2443 44 Peslnvafltqide.evekLkeaida 68 Pe+ + ++ ++e ++ +Lk a+ a FUN_000183-T1 79 PEHREDCTYQPLKEaRITQLKSAVAA 104 66666666777665357788877654 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00021 DUF2443 41 ldmPeslnva..fltqideevekLkeaidaLnkikkelL 77 d+P++l+ l++++ee +kLk+++d +k+el+ FUN_000183-T1 128 FDLPQELQGIkeDLQRLKEENDKLKAKLDDKETLKRELF 166 69999998542269***********************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (180 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1708 (0.0668624); expected 510.9 (0.02) Passed bias filter: 842 (0.0329614); expected 510.9 (0.02) Passed Vit filter: 123 (0.00481503); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1781.76 // Query: FUN_000184-T1 [L=721] Description: FUN_000184 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-66 225.6 9.5 1.2e-66 225.6 9.5 1.9 2 Zip ZIP Zinc transporter 3.9e-15 56.4 2.1 1.3e-10 41.7 0.4 2.8 3 ZIP4_domain Zinc transporter ZIP4 domain 9.3e-10 39.6 8.6 2.6e-07 31.7 1.1 4.5 4 EF-hand_Zip Zip protein EF-hand ------ inclusion threshold ------ 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 Fapy_DNA_glyco_C Formamidopyrimidine-DNA glycosylase C-termi 0.081 13.2 0.0 0.17 12.2 0.0 1.5 1 Cas8b_C Type I-B CRISPR Cas8b C-terminal domain 1.2 9.9 0.0 1.2 9.9 0.0 2.5 3 CD225 Interferon-induced transmembrane protein Domain annotation for each model (and alignments): >> Zip ZIP Zinc transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.5 0.24 1e+03 124 159 .. 259 294 .. 232 318 .. 0.71 2 ! 225.6 9.5 2.9e-70 1.2e-66 2 323 .] 373 710 .. 372 710 .. 0.81 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.24 Zip 124 eveeseekedhgseeksdadskeklkkgkeekseee 159 e+++++ +dhg++++ +++++ l +ke s+++ FUN_000184-T1 259 ETSSESTAHDHGHHHRRRRSTTAALLPRKELVSSHA 294 455666667888888888887777777777666665 PP == domain 2 score: 225.6 bits; conditional E-value: 2.9e-70 Zip 2 llkilaifaillisliglllpllvpkikklaskkllslllafaaGvllataflhllPealealeslqled....htw......pfaglivllGfll 87 +++ ++i a++lisl +l ++ +p i k+ ++k+l ll+++a+G l ++++lhllP++++ + ++++e+ h++ +++ ++vl ++++ FUN_000184-T1 373 KIWGYGIGAVTLISLTSLAGVATIPFIGKRLYNKVLDLLVGLAVGSLAGDGLLHLLPHSFGLHAHEEEEStgdsHDHsedhafIWKAMVVLASIYV 468 5799********************************************************9888887777666666699***************** PP Zip 88 vllveklltllver.......ktpkkeksshshkatvksvseeeveeseekedhgseeksdadskeklkkgkeekseeekeks......eeedkek 170 ++l+e l++l +++ + k+e++ ++ k + +++ v + +++d+++ +sd+ + e+++ g s +++k + FUN_000184-T1 469 FYLFEILTHLGLKSkflglsrHELKPEEQLRKGKTEIPKDNKDIVLMNASSKDVQDVIQSDKGDHENERVGA----------SlqprssASSKKNS 554 *********999995555544222222222222222222333333333333444444444444333333333..........23333335567789 PP Zip 171 laslrvraillllgiilHsfieGLalG..vssss....stgislliAvllHelpeglglgaiLlqagfsrkkavllallfalttplGiliGilvss 260 ++++ +a+++++g++lH++++GLa+G +s++ s gis++iAv++Help++lg++a+Ll+ag+s+k a+++++l+al++ +G++iGi FUN_000184-T1 555 WKNISAVAWMIIIGDSLHNISDGLAIGavFSQGGpsgiSGGISTSIAVFCHELPHELGDFAVLLKAGMSVKMALVANFLSALSCFIGLFIGIE--- 647 999*************************988765111167789*************************************************9... PP Zip 261 ieessgadivsgillafsAGtflYvalvellprellrek....sslklsllqllalllGfalmalla 323 ++ v +++a+++G+flYvalv++lp +l ++k + l+++llq+++ll+Gf++++++a FUN_000184-T1 648 ---VGQQGEVRLWFFAIAGGIFLYVALVDMLP-HLIHSKtlkaEPLVTFLLQNVGLLVGFGILLIIA 710 ...789999***********************.9999999***99*******************997 PP >> ZIP4_domain Zinc transporter ZIP4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.0 0.00073 3.1 74 152 .. 31 113 .. 26 118 .. 0.80 2 ! 41.7 0.4 3e-14 1.3e-10 15 158 .] 74 217 .. 56 217 .. 0.85 3 ! 13.2 0.0 1.8e-05 0.077 111 157 .. 310 355 .. 300 356 .. 0.90 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00073 ZIP4_domain 74 adqllykllslrqdedsealsqgeledlLqkir..qhyktses...eaCvdvkqLleeanvaedspgadektlpkvlaaiidhv 152 ++ +y++ +lr++ + ++l+ +e ++l ++++ + +t+++ +C+++++L e + s g +++++ + ii+ + FUN_000184-T1 31 RQHGDYSFKDLREAVNGDYLTPEEQQTLFNSLHllNCNETKNEldyRKCFTTNDLHEFEGS-SASRGLNSTEFTDISPVIIYCL 113 467899999999999********9999988888644444444477988******9987777.8999999999999999999765 PP == domain 2 score: 41.7 bits; conditional E-value: 3e-14 ZIP4_domain 15 edCekcLevdallalasggdsedvLeeeviqrlsaalllYl...snpediCasklagrwasradqllykllslrqdedsealsqgeledlLqkirq 107 d kc++ ++l g +++ L++ ++ +s ++++ l s+++++ + + + +s+ + +++ + + ++e +s ++le++L++i++ FUN_000184-T1 74 LDYRKCFTTNDLHEFE-GSSASRGLNSTEFTDISPVIIYCLlptSSQKNLVGEPCDISRKSHEQIFDAFV--SNFSKGQEGISYKGLETILKQINN 166 56689***********.*****************998888755578999988888888887777666666..5668999****************9 PP ZIP4_domain 108 hyktses.eaCvdvkqLleeanvaedspgadektlpkvlaaiidhvlqGsCl 158 ++++ + ++C+++ + +e+ e+ + d++++++ +a+ii h++qG C+ FUN_000184-T1 167 TVGQFFTkKKCFSADSIIKEVLK-EEGNTLDQNEFKRACASIILHLVQGYCI 217 9988776699************9.8999999********************5 PP == domain 3 score: 13.2 bits; conditional E-value: 1.8e-05 ZIP4_domain 111 tseseaCvdvkqLleeanvaedspgadektlpkvlaaiidhvlqGsC 157 +++s +C ++ +Ll +v ++s gad +++++++ a i+++++G+C FUN_000184-T1 310 HQTSGTCYSLDDLLTIFDV-DHSTGADRDDFQNLCPAFIQQAKSGAC 355 456678*************.*************************** PP >> EF-hand_Zip Zip protein EF-hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.0 0.0016 7 63 106 .. 69 113 .. 24 117 .. 0.82 2 ! 31.7 1.1 6e-11 2.6e-07 3 110 .] 231 354 .. 229 354 .. 0.68 3 ? -3.1 0.1 4 1.7e+04 31 49 .. 432 450 .. 419 464 .. 0.58 4 ? 0.0 0.1 0.42 1.8e+03 40 72 .. 527 559 .. 510 572 .. 0.66 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0016 EF-hand_Zip 63 ssssvWd.tlclsardvlavyGlseqaGvtpeawaqlsPallqqq 106 + ++ d + c++++d+ + G s G+ +++ +sP ++ + FUN_000184-T1 69 ETKNELDyRKCFTTNDLHEFEGSSASRGLNSTEFTDISPVIIYCL 113 4444444257*****************************998665 PP == domain 2 score: 31.7 bits; conditional E-value: 6e-11 EF-hand_Zip 3 yfvdfvfrqhsseapnitlaelealmerlgvGgeaet...hddhseee.................rkasrqgpvalta........tnssssvWdt 70 +f++ +f ++ ++ +++ +++++lg+G+++++ hd++++++ a + ++ ++ t FUN_000184-T1 231 FFINDIFM----HKSHLSREDFHEIIKSLGIGETSSEstaHDHGHHHRrrrsttaallprkelvsS----------HAvyrreidpHGNQVDAHQT 312 56666666....34567889999*********8765344588877777445555544444322211..........11222222334444444444 PP EF-hand_Zip 71 ..lclsardvlavyGlseqaGvtpeawaqlsPallqqqlsga 110 c+s d+l ++ ++ +G ++++ +l Pa++qq sga FUN_000184-T1 313 sgTCYSLDDLLTIFDVDHSTGADRDDFQNLCPAFIQQAKSGA 354 337***********************************9997 PP == domain 3 score: -3.1 bits; conditional E-value: 4 EF-hand_Zip 31 lgvGgeaethddhseeerk 49 +g+ +++e+ + +++++++ FUN_000184-T1 432 FGLHAHEEEESTGDSHDHS 450 5555544443333333222 PP == domain 4 score: 0.0 bits; conditional E-value: 0.42 EF-hand_Zip 40 hddhseeerkasrqgpvaltatnssssvWdtlc 72 +d+ ++e++ ++ ++ s++++W ++ FUN_000184-T1 527 QSDKGDHENERVGASLQPRSSASSKKNSWKNIS 559 455555555555556666777777777887764 PP >> Fapy_DNA_glyco_C Formamidopyrimidine-DNA glycosylase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 7.3e-06 0.031 13 34 .. 294 315 .. 287 318 .. 0.88 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 7.3e-06 Fapy_DNA_glyco_C 13 lVYRkkkDPlGNkVkadKiiGs 34 VYR++ DP GN+V a + G+ FUN_000184-T1 294 AVYRREIDPHGNQVDAHQTSGT 315 6*************99988775 PP >> Cas8b_C Type I-B CRISPR Cas8b C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 3.9e-05 0.17 60 141 .. 153 232 .. 124 256 .. 0.79 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.9e-05 Cas8b_C 60 wytgfdklletlpa...elfieepfFgrdvrekfkelieeekeekemkeeeaeeeeleelvyrlvksYvlskleekyglkwkkek 141 y+g++++l++++ ++f++++ F+ d +ke+ ++e ++++++e ++++++++ +lv+ Y + + e+ +l k++ FUN_000184-T1 153 SYKGLETILKQINNtvgQFFTKKKCFSADSI--IKEVL--KEEGNTLDQNEF-KRACASIILHLVQGYCIGQNETLKKLPSKAFF 232 5889999999988655688999*****9953..33333..367899999988.9****************999998888877765 PP >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00028 1.2 15 33 .. 14 32 .. 9 40 .. 0.87 2 ? -3.5 0.6 4.2 1.8e+04 46 64 .. 548 566 .. 546 567 .. 0.57 3 ? -3.1 0.3 3.1 1.3e+04 50 64 .. 630 644 .. 625 646 .. 0.58 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00028 CD225 15 fcclplGivAlvySvkvrd 33 f+++ l+i A+v+S+++r+ FUN_000184-T1 14 FWFWVLNIGAFVFSHESRQ 32 78999************96 PP == domain 2 score: -3.5 bits; conditional E-value: 4.2 CD225 46 asskAkllniislvlglvi 64 assk + is+v+ ++i FUN_000184-T1 548 ASSKKNSWKNISAVAWMII 566 5666666666666665555 PP == domain 3 score: -3.1 bits; conditional E-value: 3.1 CD225 50 Akllniislvlglvi 64 A +l+ +s +gl+i FUN_000184-T1 630 ANFLSALSCFIGLFI 644 555666666666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (721 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 840 (0.0328831); expected 510.9 (0.02) Passed bias filter: 636 (0.0248972); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 6745.51 // Query: FUN_000185-T1 [L=954] Description: FUN_000185 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-93 313.8 0.4 2.9e-93 313.3 0.4 1.2 1 ERAP1_C ERAP1-like C-terminal domain 6.1e-88 294.6 1.1 1.1e-87 293.7 1.1 1.5 1 Peptidase_M1 Peptidase family M1 domain 6.6e-54 183.3 0.3 1.1e-53 182.6 0.3 1.3 1 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.022 14.6 0.0 0.052 13.4 0.0 1.5 1 Aminopep Putative aminopeptidase 0.38 11.0 4.8 0.061 13.5 0.5 1.8 2 DUF7266 Family of unknown function (DUF7266) 7.5 6.9 6.4 57 4.1 6.2 2.4 2 DUF2970 Protein of unknown function (DUF2970) Domain annotation for each model (and alignments): >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 313.3 0.4 6.7e-97 2.9e-93 1 316 [. 609 925 .. 609 927 .. 0.95 Alignments for each domain: == domain 1 score: 313.3 bits; conditional E-value: 6.7e-97 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlkslls.ed 93 w+k+Na++ GyyrvnY ++ +++l+ q ++v+ + dRagliddaf+larag++++s a++l+k yl++E+eyv+w+a++++++t+ks+l ++ FUN_000185-T1 609 WLKANAGQRGYYRVNYGQTLWNRLGIQMEnnHEVFKSTDRAGLIDDAFNLARAGYMKYSMAFKLTK-YLRKEEEYVPWEAVITNVNTIKSILPrSS 703 9***********************7765568**********************************9.999**********************9667 PP ERAP1_C 94 pvyealkaflrkllsplleklgweekpgeshldqqlrslllsaacsagdeevvaeakklfeawlegddsaippdlrwavlcaavanggeaewdall 189 p + l++++ +l pl++klg+++ + shl+ + r+ +l+++c ag+++++++a ++f++w+e++ +++p+++r+ v+ ++++ngg +ewd+++ FUN_000185-T1 704 PSFKYLEKYIYNLSFPLYQKLGFND--TGSHLEIYKRNIVLGTMCGAGESSCLSQASRYFQNWMEKN-QSVPANFRSLVYFYGIRNGGVKEWDFAF 796 7**********************44..56***********************************975.48************************** PP ERAP1_C 190 erykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlagl.asnpagrelawdfvkenwdelekrlgggs.slgrlvkgltps 283 e++++tt+ase++++l l+ t++ ++l r+le+++ds +++ qd++ v+ ++ np+gr+law+f+k nw+ + k++ggg+ s+++++ g+t++ FUN_000185-T1 797 EQFQKTTVASERRNILFGLSGTTESWILTRYLEYSIDSTKIKAQDTSRVIYYIaNYNPQGRHLAWQFLKINWNFILKKFGGGFfSIRNVILGVTSG 892 ************************************9****************8889***********************9999************ PP ERAP1_C 284 fsteeeldeveaFfadkdtpglr.ralaqaleti 316 f+te el+e+++F ++++ +g+ ra +qa+e++ FUN_000185-T1 893 FATEFELQELKKFNENNA-AGAGaRAQQQAVERV 925 ************988885.66666********98 PP >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 293.7 1.1 2.6e-91 1.1e-87 1 218 [] 308 530 .. 308 530 .. 0.99 Alignments for each domain: == domain 1 score: 293.7 bits; conditional E-value: 2.6e-91 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 +a+++ +k+l+f+e yf + Yplpk d++a+pdf agaMEnwglityre++ll+++ +s+e++k++va v+ HElaHqWfGnlVtmkwW+dlwLnE FUN_000185-T1 308 FAMDNGIKMLQFMEGYFGIRYPLPKADMIAIPDFAAGAMENWGLITYRETALLIKSGESAETNKKRVAAVVSHELAHQWFGNLVTMKWWDDLWLNE 403 799********************************************************************************************* PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfas++ey ++++++p+wk+ +++++ ++++a++ D l++shpi+v v++++ei+e+Fd+isY+KGas++rml+ +lg++vf kgl++Yl+k+ y+ FUN_000185-T1 404 GFASFVEYYGVNATQPDWKLLDSFVVADMASAFSLDGLTNSHPIKVPVNHPDEINEIFDSISYNKGASIIRMLQYFLGKDVFLKGLNRYLNKHLYG 499 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasg.....kdvkslmdtw 218 na+t+dlw+alee++ k+vk++mdtw FUN_000185-T1 500 NAETDDLWNALEEETRsrgnfKHVKQMMDTW 530 *************77777899********** PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 182.6 0.3 2.5e-57 1.1e-53 1 186 [] 88 273 .. 88 273 .. 0.96 Alignments for each domain: == domain 1 score: 182.6 bits; conditional E-value: 2.5e-57 Peptidase_M1_N 1 vpehYdldlkinlkektfkGsvtitlqlknatssivlnakeleikkvslsaevasesvkvdfkveqkdeekltiklpeslqqtssvtLeieysge 95 vp+hYd++l+i+l++ +f+Gsvti ++++++t+++ ++ ++++i+++s+ + + + + k+ ++++ +i l++ l++++++++++ ++++ FUN_000185-T1 88 VPDHYDVELNIDLDKAEFNGSVTILVTVREPTENVLVHVNKMKITSASVEKASTGGQLGIVRKFLFEKNQFYVIILKSALEKQGQYKIKMRFKAK 182 69**********************************************999999999999999999999999999******************** PP Peptidase_M1_N 96 lndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpviesekledgkkitkFeetpkmstYL 186 l+d+laGlykstY+ +g++ +a+Tqf++tdAR+afPcfDeP+ Katf++++ ++ +++ +SNmp ++se+++ + + ++F++tpkm+tYL FUN_000185-T1 183 LTDDLAGLYKSTYKRkDGTEIAIAATQFQPTDARRAFPCFDEPALKATFSVTLGHNPKYISISNMPIESSEMKD-SLQLDHFQKTPKMPTYL 273 ***************8888899**********************************************888886.688*************9 PP >> Aminopep Putative aminopeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 1.2e-05 0.052 144 185 .. 368 415 .. 364 421 .. 0.82 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 1.2e-05 Aminopep 144 ryseeeLarlifHElaHq......tlYvkgdtafnEsfAtfveregae 185 +++++++a+++ HElaHq t+ +d +nE fA+fve g++ FUN_000185-T1 368 ETNKKRVAAVVSHELAHQwfgnlvTMKWWDDLWLNEGFASFVEYYGVN 415 568899***********9444433445679*************99986 PP >> DUF7266 Family of unknown function (DUF7266) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.5 1.4e-05 0.061 12 107 .. 20 125 .. 10 150 .. 0.70 2 ? -2.3 0.3 1.1 4.7e+03 43 68 .. 910 936 .. 903 941 .. 0.73 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.4e-05 DUF7266 12 kaLelgivvlyvallttalyGgvvpdyreaagaevadrvlaaaaarveaavplaaaavevrvrvdLPetIrgesYrirvenr............tL 95 k++ giv++++ +++++l ++v+ r++ + + +++ a+ + + ++ +++ +ev +v+LP+++ ++Y ++++ + + FUN_000185-T1 20 KVIIYGIVLVLLLIMVIVL-ASVLGYTRSKLAGNRQAKTTPATMEPTP-TIGPTTPGTEVWWKVRLPHNVVPDHYDVELNIDldkaefngsvtiLV 113 88999**************.*********9999988888888888887.5555556678******************9964433334444453333 PP DUF7266 96 vLdhpdpevsgr 107 +++ p ++v ++ FUN_000185-T1 114 TVREPTENVLVH 125 334444444333 PP == domain 2 score: -2.3 bits; conditional E-value: 1.1 DUF7266 43 gaevadrvlaaaaarveaavplaaa.a 68 +a + r+ ++a++rv a v+ +++ + FUN_000185-T1 910 AAGAGARAQQQAVERVMANVQWRKQnE 936 556688999999999999998887733 PP >> DUF2970 Protein of unknown function (DUF2970) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 6.2 0.013 57 32 50 .. 20 38 .. 16 42 .. 0.89 2 ? -0.5 0.0 0.36 1.5e+03 8 22 .. 627 641 .. 625 642 .. 0.89 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.013 DUF2970 32 hviivGvilaalFvlgLvl 50 +vii G++l++l+++++vl FUN_000185-T1 20 KVIIYGIVLVLLLIMVIVL 38 79**************998 PP == domain 2 score: -0.5 bits; conditional E-value: 0.36 DUF2970 8 VlaaffGVrseknre 22 +l+ +G++ e n+e FUN_000185-T1 627 TLWNRLGIQMENNHE 641 79999********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (954 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1136 (0.0444705); expected 510.9 (0.02) Passed bias filter: 819 (0.0320611); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.43u 0.39s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 9159.53 // Query: FUN_000186-T1 [L=453] Description: FUN_000186 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-87 292.2 1.0 9.4e-87 291.9 1.0 1.1 1 ERAP1_C ERAP1-like C-terminal domain Domain annotation for each model (and alignments): >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 291.9 1.0 3.7e-91 9.4e-87 1 317 [. 95 417 .. 95 418 .. 0.94 Alignments for each domain: == domain 1 score: 291.9 bits; conditional E-value: 3.7e-91 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlkslls.ed 93 w+k Na++ G+yrvnYd++++++l ++ + +kv+ + dRag+i+dafalar+g++++++al+l++ yl++E eyv+w aa+++++ +k ll + FUN_000186-T1 95 WIKGNAGQKGFYRVNYDDQNWDALANAFKndHKVMNVSDRAGVIGDAFALARSGKINYTKALELTS-YLPAEMEYVPWVAAVKSFNLIKELLTpTR 189 9*************************65589**********************************9.99***********************9767 PP ERAP1_C 94 pvyealkaflrkllsplleklgweekpgeshldqqlrslllsaacsagdeevvaeakklfeawlegddsa.ippdlrwavlcaavanggeaewdal 188 p+y+ l+++++++++p++e+l +++ shl+++l+ +l ++c+ag++ ++ +a ++f++w++++ + +p+++r+ v+ +++angg++ew++ FUN_000186-T1 190 PAYKLLQRYVLRQAKPIYERLEFTD--RGSHLESLLQPIILDTVCAAGEKLCLLNASNYFHEWMKDPRRKqVPANFRSLVYYYGIANGGREEWEFS 283 7**********************66..459*********************************99888555************************* PP ERAP1_C 189 lerykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlagl.asnpagrelawdfvkenwdelekrlgggs.slgrlvkgltp 282 ++++ +t++asek++++r laa+ +p++l r+l+l+ld+d +++ d+ +v++ + +++ gr+lawdf+ ++w++l++r+++g +l rl++ +t FUN_000186-T1 284 FNQFLSTSVASEKNTLMRGLAASSEPWILSRYLQLSLDTDVIKSSDTPMVISRVaEASHIGRQLAWDFILRHWKTLKTRYSEGLnVLKRLLEDVTA 379 ******************************************************8888**********************9766699********* PP ERAP1_C 283 sfsteeeldeveaFfadkdtpglr....ralaqaletir 317 +f++e +l++v +F ++ d +g+ +l+qa+e i+ FUN_000186-T1 380 GFTNEFQLQQVINFAKSYD-HGYGkdnlASLSQAIEVIK 417 ***************9995.3333225568888888886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (453 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 709 (0.0277549); expected 510.9 (0.02) Passed bias filter: 564 (0.0220787); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4515.73 // Query: FUN_000186-T2 [L=418] Description: FUN_000186 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-84 282.6 0.9 8e-84 282.2 0.9 1.1 1 ERAP1_C ERAP1-like C-terminal domain Domain annotation for each model (and alignments): >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 282.2 0.9 3.1e-88 8e-84 1 293 [. 95 390 .. 95 393 .. 0.96 Alignments for each domain: == domain 1 score: 282.2 bits; conditional E-value: 3.1e-88 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlkslls.ed 93 w+k Na++ G+yrvnYd++++++l ++ + +kv+ + dRag+i+dafalar+g++++++al+l++ yl++E eyv+w aa+++++ +k ll + FUN_000186-T2 95 WIKGNAGQKGFYRVNYDDQNWDALANAFKndHKVMNVSDRAGVIGDAFALARSGKINYTKALELTS-YLPAEMEYVPWVAAVKSFNLIKELLTpTR 189 9*************************65589**********************************9.99***********************9767 PP ERAP1_C 94 pvyealkaflrkllsplleklgweekpgeshldqqlrslllsaacsagdeevvaeakklfeawlegddsa.ippdlrwavlcaavanggeaewdal 188 p+y+ l+++++++++p++e+l +++ shl+++l+ +l ++c+ag++ ++ +a ++f++w++++ + +p+++r+ v+ +++angg++ew++ FUN_000186-T2 190 PAYKLLQRYVLRQAKPIYERLEFTD--RGSHLESLLQPIILDTVCAAGEKLCLLNASNYFHEWMKDPRRKqVPANFRSLVYYYGIANGGREEWEFS 283 7**********************66..459*********************************99888555************************* PP ERAP1_C 189 lerykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlagl.asnpagrelawdfvkenwdelekrlgggs.slgrlvkgltp 282 ++++ +t++asek++++r laa+ +p++l r+l+l+ld+d +++ d+ +v++ + +++ gr+lawdf+ ++w++l++r+++g +l rl++ +t FUN_000186-T2 284 FNQFLSTSVASEKNTLMRGLAASSEPWILSRYLQLSLDTDVIKSSDTPMVISRVaEASHIGRQLAWDFILRHWKTLKTRYSEGLnVLKRLLEDVTA 379 ******************************************************8888**********************9766699********* PP ERAP1_C 283 sfsteeeldev 293 +f++e +l++v FUN_000186-T2 380 GFTNEFQLQQV 390 *********97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (418 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 772 (0.0302212); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4009.44 // Query: FUN_000187-T1 [L=145] Description: FUN_000187 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-25 91.0 0.2 1.7e-25 90.4 0.2 1.3 1 Peptidase_M1 Peptidase family M1 domain 0.0011 19.6 1.3 0.017 15.7 0.1 2.2 2 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.15 12.7 0.2 0.22 12.2 0.2 1.3 1 Collagen_bind Collagen binding domain Domain annotation for each model (and alignments): >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.4 0.2 2e-29 1.7e-25 4 78 .. 66 140 .. 63 142 .. 0.96 Alignments for each domain: == domain 1 score: 90.4 bits; conditional E-value: 2e-29 Peptidase_M1 4 evtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHq 78 ++t ll+ffeeyf+++Y+lpk+d++a+p+f gaMEnwglityr+ ll++ + ss+ +k++vaev+ HElaHq FUN_000187-T1 66 KITDSLLTFFEEYFDIKYALPKVDMIAIPNFLHGAMENWGLITYRDLNLLYKANISSSFHKQRVAEVVSHELAHQ 140 567889********************************************************************9 PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.1 2.1e-06 0.017 159 186 .] 1 28 [. 1 28 [. 0.95 2 ? 3.1 0.1 0.015 1.3e+02 89 109 .. 60 80 .. 35 87 .. 0.78 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2.1e-06 Peptidase_M1_N 159 mpviesekledgkkitkFeetpkmstYL 186 mp +s +++dg++++kF+++ mstYL FUN_000187-T1 1 MPIYQSRQEKDGWTYDKFQKSAVMSTYL 28 78889999*******************9 PP == domain 2 score: 3.1 bits; conditional E-value: 0.015 Peptidase_M1_N 89 eieysgelndklaGlykstYt 109 ++ey+ +++d+l ++++++ FUN_000187-T1 60 QVEYVSKITDSLLTFFEEYFD 80 699*************97664 PP >> Collagen_bind Collagen binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.2 2.5e-05 0.22 77 120 .. 39 85 .. 4 93 .. 0.80 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 2.5e-05 Collagen_bind 77 idldtdngFkvtfgdtidsaviisYtTtitdsgksq...syknkatl 120 + + +n Fkv+++ + ++ +++Y ++itds + ++++k+ l FUN_000187-T1 39 VEVAHNNSFKVRIYTPQEQIDQVEYVSKITDSLLTFfeeYFDIKYAL 85 5667899************************9876444467777666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (145 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 840 (0.0328831); expected 510.9 (0.02) Passed bias filter: 544 (0.0212958); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1499.83 // Query: FUN_000188-T1 [L=182] Description: FUN_000188 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-09 37.4 0.0 5e-09 37.0 0.0 1.2 1 Peptidase_M1_N Peptidase M1 N-terminal domain Domain annotation for each model (and alignments): >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.0 0.0 2e-13 5e-09 2 58 .. 108 161 .. 107 180 .. 0.84 Alignments for each domain: == domain 1 score: 37.0 bits; conditional E-value: 2e-13 Peptidase_M1_N 2 pehYdldlkinlkektfkGsvtitlqlknatssivlnakeleikkvslsaevasesv 58 p+hYd++++++lk+++f+G+v+i ++++n+t+ + l+a+el ++ vs+++ ++++ FUN_000188-T1 108 PKHYDVTVRVDLKKFKFNGHVSILINVTNPTEYVLLHANELRVTLVSAQT---IKGS 161 99*****************************************6665554...3333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1099 (0.0430221); expected 510.9 (0.02) Passed bias filter: 810 (0.0317087); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1792.77 // Query: FUN_000189-T1 [L=193] Description: FUN_000189 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-07 30.5 0.1 6.5e-07 29.9 0.1 1.4 1 Myb_DNA-binding Myb-like DNA-binding domain 7.4e-05 23.0 0.4 0.00011 22.4 0.4 1.2 1 Myb_DNA-bind_7 Myb DNA-binding like ------ inclusion threshold ------ 0.032 14.9 0.1 0.051 14.3 0.1 1.3 1 Myb_DNA-bind_6 Myb-like DNA-binding domain 0.081 13.2 0.3 0.11 12.8 0.3 1.2 1 DUF4456 Domain of unknown function (DUF4456) 0.12 11.3 0.7 0.14 11.1 0.7 1.0 1 LCD1 DNA damage checkpoint protein Domain annotation for each model (and alignments): >> Myb_DNA-binding Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.1 1.3e-10 6.5e-07 2 40 .. 49 87 .. 48 93 .. 0.95 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 1.3e-10 Myb_DNA-binding 2 gpWtpeEdelLleaveklGnrWkkIakllpgRtdkqckn 40 g+W +eE e L +av+++G++ kkI+ ++ g++ q+k+ FUN_000189-T1 49 GKWGDEEIEMLRSAVKRFGEDLKKISGQVKGKSVAQIKS 87 89***********************************97 PP >> Myb_DNA-bind_7 Myb DNA-binding like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.4 2.2e-08 0.00011 7 73 .. 47 113 .. 44 125 .. 0.87 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 2.2e-08 Myb_DNA-bind_7 7 ktkkWskeetekFYkaLsqfGtDFsliaklfpertrrqiKlKfkrEerknpelvekalkekkkidle 73 ++ kW +ee e+ +a+++fG D++ i+ ++++ qiK+ k+ ++ + +++a k+k+k++ + FUN_000189-T1 47 NSGKWGDEEIEMLRSAVKRFGEDLKKISGQVKGKSVAQIKSALKKKLHEHDSSLSNAQKSKTKTQQA 113 6789*****************************************************9999985443 PP >> Myb_DNA-bind_6 Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.1 1e-05 0.051 1 55 [. 51 108 .. 51 113 .. 0.77 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1e-05 Myb_DNA-bind_6 1 WteeEdekLiqlvekygndWkqIakel.grRtpkqcrerwkrkl...kpkikrspwske 55 W +eE e L++ v+++g d k+I+ ++ g ++ q++ + k+kl ++++++++ sk+ FUN_000189-T1 51 WGDEEIEMLRSAVKRFGEDLKKISGQVkG-KSVAQIKSALKKKLhehDSSLSNAQKSKT 108 999************************66.99988888888755222555555555555 PP >> DUF4456 Domain of unknown function (DUF4456) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.3 2.2e-05 0.11 51 109 .. 54 112 .. 45 116 .. 0.91 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2.2e-05 DUF4456 51 sslqelReqverleellskvpelilesllkkhaqkleeamkaiaeeFekkqkklealkk 109 + + lR++v+r+ e l+k++ + + + +++l+++ +++ +++++ qk+ +++++ FUN_000189-T1 54 EEIEMLRSAVKRFGEDLKKISGQVKGKSVAQIKSALKKKLHEHDSSLSNAQKSKTKTQQ 112 56788*********************************************999888766 PP >> LCD1 DNA damage checkpoint protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.7 2.7e-05 0.14 29 89 .. 50 126 .. 25 149 .. 0.62 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 2.7e-05 LCD1 29 ssheeelekLkkevqkLeDekkFlelelrslsat............sqaasksaeeetadssevs..............lKkRKiee 89 + +ee+e+L+++v++ + k + +++ +s + ++++ ++a + +KkRKie FUN_000189-T1 50 KWGDEEIEMLRSAVKRFGEDLKKISGQVKGKSVAqiksalkkklheHDSSLSNA----------QksktktqqatdaphSKKRKIEG 126 456899**********97666667777777776656655555555322222222..........1333444445588889****985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (193 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2079 (0.0813858); expected 510.9 (0.02) Passed bias filter: 1209 (0.0473282); expected 510.9 (0.02) Passed Vit filter: 109 (0.00426698); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 1943.45 // Query: FUN_000190-T1 [L=277] Description: FUN_000190 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-07 31.8 0.6 4.2e-07 30.9 0.4 1.6 1 TEX33 Testis-expressed sequence 33 protein family Domain annotation for each model (and alignments): >> TEX33 Testis-expressed sequence 33 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.4 1.7e-11 4.2e-07 34 128 .. 90 184 .. 68 189 .. 0.78 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 1.7e-11 TEX33 34 eeqkrasswlsktqspvktssifsdyseLgyslrsnllqGapq.etksLmkasytkevieksvrdvehwhgRktDdlgrWheknalnlnLqkalee 128 + ++s+ +++ ++ ++ +i+ y +L+ lrsn+++G + e s + +t+ + + e + g +tD+ g+W n+l+ +++k +++ FUN_000190-T1 90 AAKTKRSNLSKRPKASDRSFQITEYYDNLSVALRSNVFPGLGNnEWNSTTAKVFTEK-HVTPLTQGETFFGIQTDEHGKWSAANVLHERMKKKWND 184 4444444444444444444478888999************99879999999999965.556677899***************************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (277 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 909 (0.0355843); expected 510.9 (0.02) Passed bias filter: 531 (0.0207868); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2808.48 // Query: FUN_000191-T1 [L=143] Description: FUN_000191 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-26 93.0 0.0 1.6e-26 92.7 0.0 1.1 1 Thioredoxin Thioredoxin 1.1e-09 39.1 0.1 1.2e-08 35.7 0.1 2.1 1 Thioredoxin_2 Thioredoxin-like domain 2e-06 28.3 0.0 3.9e-06 27.4 0.0 1.4 1 Thioredoxin_7 Thioredoxin-like 5.2e-06 27.3 0.0 0.00097 20.0 0.0 2.5 2 Thioredoxin_8 Thioredoxin-like 0.00038 20.9 0.0 0.00083 19.8 0.0 1.6 1 DUF6568 Family of unknown function (DUF6568) 0.00058 20.3 0.0 0.00084 19.8 0.0 1.2 1 Thioredoxin_3 Thioredoxin domain 0.0027 18.5 0.0 0.004 17.9 0.0 1.3 1 Glrx-like Glutaredoxin-like domain (DUF836) 0.0057 17.1 0.0 0.0074 16.7 0.0 1.2 1 AhpC-TSA AhpC/TSA family ------ inclusion threshold ------ 0.02 15.1 0.0 0.059 13.6 0.0 1.6 2 DSBA DSBA-like thioredoxin domain Domain annotation for each model (and alignments): >> Thioredoxin Thioredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.7 0.0 5.8e-30 1.6e-26 5 102 .. 42 139 .. 38 140 .. 0.96 Alignments for each domain: == domain 1 score: 92.7 bits; conditional E-value: 5.8e-30 Thioredoxin 5 ltkenFeeevakskklvlvdFyApwCGpCkalaPeleelaeelkdkvklakvdvdenkelakkyevegiPtlklfkngkevekyegarekeelaaf 100 k++Fe+ v +s+k+vlvdF A+wC pCkal+P+l+++ e ++++lakvd+d+n+ela +y+v+g+Pt++ +kngk ++ ++g e e+l++f FUN_000191-T1 42 KDKDDFEKRVLSSSKPVLVDFHAEWCAPCKALSPKLDSVIGENDGQLELAKVDIDTNSELALEYKVTGVPTVLGVKNGKIIDAFTGLAETEQLRRF 137 57889*****************************************************************************************99 PP Thioredoxin 101 ik 102 ++ FUN_000191-T1 138 VE 139 97 PP >> Thioredoxin_2 Thioredoxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.7 0.1 4.1e-12 1.2e-08 4 102 .. 54 136 .. 51 138 .. 0.84 Alignments for each domain: == domain 1 score: 35.7 bits; conditional E-value: 4.1e-12 Thioredoxin_2 4 ngkpvlvvftdpdCpyCkklkkelkelddvtkylkeefefkavniwcakerakafkdieeekelarkygvrgtPtiv.fldgkeevarlpGyvpae 98 + kpvlv f++++C Ck+l +l+++ ++e+ + + + + + i++++ela +y+v+g+Pt++ + +gk +++ ++G+ e FUN_000191-T1 54 SSKPVLVDFHAEWCAPCKALSPKLDSV------IGEN-DGQLELAKVD---------IDTNSELALEYKVTGVPTVLgVKNGK-IIDAFTGLAETE 132 689************************......8888.3333333333.........556799************99899999.********9999 PP Thioredoxin_2 99 elaa 102 +l++ FUN_000191-T1 133 QLRR 136 9875 PP >> Thioredoxin_7 Thioredoxin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 1.4e-09 3.9e-06 15 79 .. 53 114 .. 48 117 .. 0.86 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 1.4e-09 Thioredoxin_7 15 ergkpvlvdlqadwcftCqvlerdvlsdeevkaalrknfvllrldwtsrdenireldesgvPvva 79 ++ kpvlvd++a+wc +C++l ++ ++ + + + l ++d+++++e +e++ +gvP+v+ FUN_000191-T1 53 SSSKPVLVDFHAEWCAPCKALSPKLD--SVIGE-NDGQLELAKVDIDTNSELALEYKVTGVPTVL 114 578*******************9996..57888.8899999999999999866687889999986 PP >> Thioredoxin_8 Thioredoxin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 3.4e-07 0.00097 2 46 .. 56 98 .. 55 100 .. 0.90 2 ! 7.5 0.0 0.0026 7.4 65 94 .] 93 121 .. 79 121 .. 0.76 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 3.4e-07 Thioredoxin_8 2 kvvlLyfgaseckkckkflpkLkelykklkkkkkveiVyvsldrd 46 k+vl++f+a++c +ck++ pkL ++ ++ ++e+ v +d++ FUN_000191-T1 56 KPVLVDFHAEWCAPCKALSPKLDSVIGEND--GQLELAKVDIDTN 98 89**********************999997..8999999998865 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0026 Thioredoxin_8 65 fddderkklanklkvseiPtlvvld.kdgev 94 +d d++++la ++kv+++Pt vl+ k+g++ FUN_000191-T1 93 VDIDTNSELALEYKVTGVPT--VLGvKNGKI 121 4446788*************..777777775 PP >> DUF6568 Family of unknown function (DUF6568) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 2.9e-07 0.00083 2 96 .. 40 128 .. 39 142 .. 0.80 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 2.9e-07 DUF6568 2 nsltveefkakvkkkek.lfvYvGRPsCgdCnaFepiLkklikeekledklyyvNvdrlredkkawaalkkkydidsvPtlvklkkgkllskldle 96 n + +++f+++v ++ k ++v + C C+a p+L +i e++ + l+ v +d +l +y++++vPt++ +k+gk+++ + FUN_000191-T1 40 NVKDKDDFEKRVLSSSKpVLVDFHAEWCAPCKALSPKLDSVIGENDGQLELAKVDIDT-------NSELALEYKVTGVPTVLGVKNGKIIDAFTGL 128 566788999999888554999999999****************998887776665554.......3467789*****************9987654 PP >> Thioredoxin_3 Thioredoxin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 3e-07 0.00084 10 75 .. 67 138 .. 58 139 .. 0.86 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 3e-07 Thioredoxin_3 10 CakCpklekavkeavaelgieaevekv..tdfkei.akygVmstPal..vidgkvv..ssGkvpseeeikell 75 Ca C++l + ++ e++ ++e+ kv +++e+ +y+V+ +P++ v +gk+ ++G + ++e+++ ++ FUN_000191-T1 67 CAPCKALSPKLDSVIGENDGQLELAKVdiDTNSELaLEYKVTGVPTVlgVKNGKIIdaFTG-LAETEQLRRFV 138 ******************999999988867888999***********99999**9544999.88999988876 PP >> Glrx-like Glutaredoxin-like domain (DUF836) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-06 0.004 9 57 .. 66 117 .. 62 139 .. 0.73 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-06 Glrx-like 9 gCglCeeaeevLeelaledg..lelevidIdedeeleekYqle.ipvlalvg 57 C C+ ++ +L + e++ lel ++dId++ el +Y+ + +p ++ v+ FUN_000191-T1 66 WCAPCKALSPKLDSVIGENDgqLELAKVDIDTNSELALEYKVTgVPTVLGVK 117 6999**********76666567******************976477555554 PP >> AhpC-TSA AhpC/TSA family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 2.6e-06 0.0074 21 100 .. 50 127 .. 35 138 .. 0.69 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 2.6e-06 AhpC-TSA 21 sdl.kgkwvvLffypkdwtpvCttelpalaelyeefkekgvevlgvsvdspeshkkfaekeelpfpllsDpkgevaraygv 100 + l + k+v++ f+++ w+ +C++ p+l + e + +e+ v +d+ ++++ + ++p+ l ++g++++a+ FUN_000191-T1 50 RVLsSSKPVLVDFHAE-WCAPCKALSPKLDSVIGEND-GQLELAKVDIDTNSELALEYKVTGVPTVLGV-KNGKIIDAFTG 127 33323478********.****************9999.6799999999998876655555544433333.46666666655 PP >> DSBA DSBA-like thioredoxin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.14 3.9e+02 10 41 .. 67 97 .. 61 100 .. 0.84 2 ? 13.6 0.0 2.1e-05 0.059 149 188 .. 92 136 .. 87 139 .. 0.86 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.14 DSBA 10 CPyCylakerleklaaqspdvkvrlrpfdlag 41 C C++ +++l++++ + d +++l +d++ FUN_000191-T1 67 CAPCKALSPKLDSVIGEN-DGQLELAKVDIDT 97 999*************99.7777777777765 PP == domain 2 score: 13.6 bits; conditional E-value: 2.1e-05 DSBA 149 keavrentaaaislgvtGvPtvvv..ggk...mvfGadrldtlae 188 k +++n ++a +++vtGvPtv+ +gk +++G ++l++ FUN_000191-T1 92 KVDIDTNSELALEYKVTGVPTVLGvkNGKiidAFTGLAETEQLRR 136 678999****************97789989999999999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (143 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 474 (0.0185555); expected 510.9 (0.02) Passed bias filter: 454 (0.0177726); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1438.93 // Query: FUN_000191-T2 [L=115] Description: FUN_000191 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-20 73.0 0.0 2.8e-20 72.7 0.0 1.1 1 Thioredoxin Thioredoxin 2.2e-05 25.0 0.0 3.1e-05 24.5 0.0 1.4 1 Thioredoxin_7 Thioredoxin-like 8.1e-05 23.4 0.0 0.00079 20.2 0.0 2.1 1 Thioredoxin_2 Thioredoxin-like domain 0.00012 22.9 0.0 0.00026 21.8 0.0 1.6 2 Thioredoxin_8 Thioredoxin-like 0.0058 17.4 0.0 0.0095 16.7 0.0 1.3 1 Glrx-like Glutaredoxin-like domain (DUF836) ------ inclusion threshold ------ 0.012 16.0 0.0 0.016 15.6 0.0 1.2 1 AhpC-TSA AhpC/TSA family Domain annotation for each model (and alignments): >> Thioredoxin Thioredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.7 0.0 6.5e-24 2.8e-20 5 76 .. 42 113 .. 38 115 .] 0.95 Alignments for each domain: == domain 1 score: 72.7 bits; conditional E-value: 6.5e-24 Thioredoxin 5 ltkenFeeevakskklvlvdFyApwCGpCkalaPeleelaeelkdkvklakvdvdenkelakkyevegiPtl 76 k++Fe+ v +s+k+vlvdF A+wC pCkal+P+l+++ e ++++lakvd+d+n+ela +y+v++ P l FUN_000191-T2 42 KDKDDFEKRVLSSSKPVLVDFHAEWCAPCKALSPKLDSVIGENDGQLELAKVDIDTNSELALEYKVRARPRL 113 57889****************************************************************987 PP >> Thioredoxin_7 Thioredoxin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.0 7.2e-09 3.1e-05 15 40 .. 53 78 .. 45 114 .. 0.76 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 7.2e-09 Thioredoxin_7 15 ergkpvlvdlqadwcftCqvlerdvl 40 ++ kpvlvd++a+wc +C++l ++ FUN_000191-T2 53 SSSKPVLVDFHAEWCAPCKALSPKLD 78 578****************9987664 PP >> Thioredoxin_2 Thioredoxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 1.9e-07 0.00079 4 77 .. 54 111 .. 51 115 .] 0.71 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 1.9e-07 Thioredoxin_2 4 ngkpvlvvftdpdCpyCkklkkelkelddvtkylkeefefkavniwcakerakafkdieeekelarkygvrgtP 77 + kpvlv f++++C Ck+l +l+++ ++e+ + + + + + i++++ela +y+vr+ P FUN_000191-T2 54 SSKPVLVDFHAEWCAPCKALSPKLDSV------IGEN-DGQLELAKVD---------IDTNSELALEYKVRARP 111 68**********************999......6666.2222222222.........34457777777777766 PP >> Thioredoxin_8 Thioredoxin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 3.7 1.6e+04 57 74 .. 32 48 .. 25 51 .. 0.56 2 ! 21.8 0.0 6e-08 0.00026 2 47 .. 56 99 .. 54 113 .. 0.88 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 3.7 Thioredoxin_8 57 mkpwlslpfddderkkla 74 ++ pf+ +++ ++ FUN_000191-T2 32 S-SYFRAPFNVKDKDDFE 48 4.4555666666665555 PP == domain 2 score: 21.8 bits; conditional E-value: 6e-08 Thioredoxin_8 2 kvvlLyfgaseckkckkflpkLkelykklkkkkkveiVyvsldrde 47 k+vl++f+a++c +ck++ pkL ++ ++ ++e+ v +d++ FUN_000191-T2 56 KPVLVDFHAEWCAPCKALSPKLDSVIGEND--GQLELAKVDIDTNS 99 89***********************99997..99999999999654 PP >> Glrx-like Glutaredoxin-like domain (DUF836) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 2.2e-06 0.0095 8 48 .. 65 107 .. 62 111 .. 0.86 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 2.2e-06 Glrx-like 8 pgCglCeeaeevLeelaledg..lelevidIdedeeleekYql 48 + C C+ ++ +L + e++ lel ++dId++ el +Y+ FUN_000191-T2 65 EWCAPCKALSPKLDSVIGENDgqLELAKVDIDTNSELALEYKV 107 56999**********76666567**************999986 PP >> AhpC-TSA AhpC/TSA family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 3.8e-06 0.016 20 71 .. 49 99 .. 35 110 .. 0.74 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 3.8e-06 AhpC-TSA 20 lsdl.kgkwvvLffypkdwtpvCttelpalaelyeefkekgvevlgvsvdspe 71 + l + k+v++ f+++ w+ +C++ p+l + e + +e+ v +d+ + FUN_000191-T2 49 KRVLsSSKPVLVDFHAE-WCAPCKALSPKLDSVIGEND-GQLELAKVDIDTNS 99 333323478********.**************999988.56777777777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 405 (0.0158544); expected 510.9 (0.02) Passed bias filter: 379 (0.0148366); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1189.92 // Query: FUN_000192-T1 [L=201] Description: FUN_000192 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-73 245.8 0.6 3.5e-73 245.6 0.6 1.0 1 Nt_Gln_amidase N-terminal glutamine amidase Domain annotation for each model (and alignments): >> Nt_Gln_amidase N-terminal glutamine amidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 245.6 0.6 1.4e-77 3.5e-73 1 183 [. 20 195 .. 20 196 .. 0.97 Alignments for each domain: == domain 1 score: 245.6 bits; conditional E-value: 1.4e-77 Nt_Gln_amidase 1 ytscYCEENvyklceklkeekeaekeklfvvfisnekktvplwkqkaskeedelvvWdYHvillekekkkekeeslvyDlDstLpfpveleeYve 95 ytscYCEENv+klce++k+ek++ +++ f+vf+snek++vplw qk++k++ +vvWdYHvill+ + + ++lvyDlDs Lpfp+++e+Y + FUN_000192-T1 20 YTSCYCEENVWKLCEQIKNEKKEILNEHFAVFVSNEKRQVPLWMQKSAKDPLAPVVWDYHVILLR----QVEGRCLVYDLDSILPFPCPFEQYSQ 110 9***************************************************************4....45677********************* PP Nt_Gln_amidase 96 etlkedkklkeelkrlfrvveakkylkkfasDRshmkdedgkylkppPeyppiekkesksnLdefismseeeeeklGevlseeelvel 183 +++++dk+lk++++r+frv++a+++l++fasDRshmk+++g+++k+pP+y pi+++es++nL+efi+m+ee + Gev++ + +v+ FUN_000192-T1 111 QAIQNDKQLKKKFHRKFRVLPAEVFLRTFASDRSHMKTPNGEWIKAPPPYSPIRTSESTMNLEEFIDMTEE---GEGEVMDYKAFVRN 195 **********************************************************************9...56******999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1200 (0.0469759); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2016.57 // Query: FUN_000193-T1 [L=172] Description: FUN_000193 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-30 106.0 0.0 3.4e-30 105.8 0.0 1.0 1 Glyco_tran_28_C Glycosyltransferase family 28 C-terminal dom ------ inclusion threshold ------ 0.071 12.8 0.0 0.092 12.4 0.0 1.1 1 Glyco_trans_1_3 Glycosyl transferase family 1 0.085 13.3 0.1 0.15 12.5 0.1 1.4 1 Exonuc_VII_S Exonuclease VII small subunit 0.24 11.7 0.0 0.38 11.1 0.0 1.4 1 NAD_binding_10 NAD(P)H-binding Domain annotation for each model (and alignments): >> Glyco_tran_28_C Glycosyltransferase family 28 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.8 0.0 5.3e-34 3.4e-30 1 148 [. 10 152 .. 10 162 .. 0.92 Alignments for each domain: == domain 1 score: 105.8 bits; conditional E-value: 5.3e-34 Glyco_tran_28_C 1 tilVtGGSqgaealnelvlkekkllelk.r.elqvlhqtGkgdleelkiqlselginvevfefidnmaeyikaadlvIsRAGAgtiaEllalgk 92 +++Vt+G+++++ l+e++ ek+ lk + + +++q+G+ +e+++ q+ +++ ++ ++++d++a++i++a+lvIs+AGAg+++E+l++gk FUN_000193-T1 10 VVFVTVGTTSFDQLIETASNEKFIELLKrKgYQSLVLQIGRAVSEPQSLQRDDFS--MQHYRYKDSIAADIQRASLVISHAGAGSVLEVLHAGK 101 69********************998888435789**************9999997..999********************************** PP Glyco_tran_28_C 93 paIlvPlpsaaenhqdnNakelvkkgaalvllqkeltpekLeeallklllekekla 148 p+I+v+++ ++dn+++el++++ ++ +l++ + ++L e++++ l ++++ FUN_000193-T1 102 PLIVVINEL----LMDNHQLELASQLSEEGHLYYAT-CRTLLETVKERDLSLLNPY 152 *********....********************999.9999999998777666655 PP >> Glyco_trans_1_3 Glycosyl transferase family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.4e-05 0.092 202 280 .. 26 106 .. 17 120 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.4e-05 Glyco_trans_1_3 202 tstanealaevLkqvgvefrvyGlrrdlteegv..egnltykpf.seegfldDLatakaviagagftLvteavyLkkPlLav 280 t+ +ne++ e+Lk+ g + v ++r ++e + ++ +++ ++ +D++ a vi+ ag v e ++ kPl+ v FUN_000193-T1 26 TA-SNEKFIELLKRKGYQSLVLQIGRAVSEPQSlqRDDFSMQHYrYKDSIAADIQRASLVISHAGAGSVLEVLHAGKPLIVV 106 55.899********************99986531133444444414677889**************************9876 PP >> Exonuc_VII_S Exonuclease VII small subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 2.4e-05 0.15 11 49 .. 106 144 .. 101 144 .. 0.88 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2.4e-05 Exonuc_VII_S 11 IvekLEsgelsLeeslklyeeGikLlkeCekkLeeaeqk 49 ++++L ++ Le + +l eeG ++ C++ Le+++++ FUN_000193-T1 106 VINELLMDNHQLELASQLSEEGHLYYATCRTLLETVKER 144 56777778889************************9986 PP >> NAD_binding_10 NAD(P)H-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 5.9e-05 0.38 57 130 .. 4 78 .. 1 98 [. 0.75 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 5.9e-05 NAD_binding_10 57 alkgadaVisalggggtdeeg....akniidaakeagvkrfilvsalgvgdevpgkfgewnkevlkaylaakraaeel 130 ++g ++V++++g+++ d+ + ++ i+ +k++g + ++l + v++ p+++++ ++ +++y + a+++ FUN_000193-T1 4 KMEGENVVFVTVGTTSFDQLIetasNEKFIELLKRKGYQSLVLQIGRAVSE--PQSLQR-DDFSMQHYRYKDSIAADI 78 699*********9988743335556******************88888885..444444.455667775444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (172 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 611 (0.0239186); expected 510.9 (0.02) Passed bias filter: 557 (0.0218047); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.42 # Mc/sec: 1668.75 // Query: FUN_000194-T1 [L=621] Description: FUN_000194 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-91 306.3 2.0 3.7e-91 305.8 0.0 2.0 2 PIP5K Phosphatidylinositol-4-phosphate 5-Kinase Domain annotation for each model (and alignments): >> PIP5K Phosphatidylinositol-4-phosphate 5-Kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 305.8 0.0 1.4e-95 3.7e-91 3 287 .. 164 480 .. 162 481 .. 0.90 2 ? -2.0 1.7 0.094 2.4e+03 188 202 .. 520 544 .. 489 598 .. 0.47 Alignments for each domain: == domain 1 score: 305.8 bits; conditional E-value: 1.4e-95 PIP5K 3 skeilselsspGkSgsffylskDdrfiiKtikksEvkflrkilpeYyehvkenpntLltkfyglhrvklkggkkirfvVmnnlfptelkiherYDL 98 ++e+l el+++G+Sgs+fy+++Dd+fi+Kt++++E++fl+k+lp Yy ++++n++tLl+kf+gl+++++ ggk+ir+v+mnnl+p+ +kih +YDL FUN_000194-T1 164 CNEPLVELTNSGASGSLFYVTNDDEFIVKTVQHKEAEFLQKLLPGYYLNLNQNKRTLLPKFFGLYCYQC-GGKNIRLVIMNNLLPRVYKIHFKYDL 258 8999***************************************************************98.************************** PP PIP5K 99 KGstvgReakkkekekeektvlkDlDllekkkk.lklgpekreellkqlerDvefLeslnimDYSLLlGihdlekeekeeskekessseeeesese 193 KGst++R+a+k+e++ke++t lkDlD+l+++ + l l+p+++++ ++ ++rD+++L+s++imDYSLL++ih++e++ + ++k++ s+ ++++ + FUN_000194-T1 259 KGSTYKRKASKAERAKETPT-LKDLDFLNDHPEgLFLEPDTYTAVMRIIQRDCRVLQSFKIMDYSLLVAIHKVEEAGHPRMKRSYSEPSSDNPLKP 353 *************9999888.*********9889************************************99998777666666555544443333 PP PIP5K 194 eeesssee....................................ekeeeeeseeeeksekkedeegeraseeesedekeiyylGiIDiLqeYnlkK 253 ++ s + ++ +++ e+ + +++e+++ +++++ ++e+ +++lGiIDiLq+Y++ K FUN_000194-T1 354 DSLS---DvisdntqtstngqhltvastpddnysplkrarslkaREGFSSAWEAITVGDETEERPVGGIPARNAKGERLLLFLGIIDILQSYRIVK 446 3322...124467889999********************99876555566666677778888889999**************************** PP PIP5K 254 klehalkslkkdgksisavpPkeYaeRFlkfiek 287 +leh +ks+ +dg+++s+++P++Y+ RF++f+++ FUN_000194-T1 447 RLEHGWKSIVHDGDTVSVHRPSFYCTRFQEFMSN 480 ********************************98 PP == domain 2 score: -2.0 bits; conditional E-value: 0.094 PIP5K 188 eeseseeeesssee..............e 202 +es++++++ + + FUN_000194-T1 520 NESSTSDKQ----RprsfsgtaekrvekT 544 111111111....1111122222222220 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (621 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 933 (0.0365238); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.41u 0.41s 00:00:00.82 Elapsed: 00:00:00.47 # Mc/sec: 5320.44 // Query: FUN_000195-T1 [L=188] Description: FUN_000195 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-20 74.1 0.0 2.4e-20 73.6 0.0 1.3 1 Formyl_trans_N Formyl transferase ------ inclusion threshold ------ 0.034 14.5 0.0 0.058 13.8 0.0 1.3 1 HTH_Tnp_Tc3_1 Tc3 transposase Domain annotation for each model (and alignments): >> Formyl_trans_N Formyl transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.6 0.0 1.8e-24 2.4e-20 76 140 .. 100 164 .. 19 170 .. 0.70 Alignments for each domain: == domain 1 score: 73.6 bits; conditional E-value: 1.8e-24 Formyl_trans_N 76 kalaadlivlagymkilpkelvqaprgkilniHpSLLPkfrGaaaiqraleaGdketGvtihfvd 140 a + d+ ++a+++ ++p++++++++ +++niHpSLLP+++Ga++i +a++ G+ketGv+i v FUN_000195-T1 100 PASQYDIGIVASFGHLIPNHVLDMFPCGAINIHPSLLPQWKGASPISQAILTGAKETGVSIVEVS 164 45678999*****************************************************9887 PP >> HTH_Tnp_Tc3_1 Tc3 transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 4.5e-06 0.058 8 37 .. 145 174 .. 141 177 .. 0.88 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 4.5e-06 HTH_Tnp_Tc3_1 8 tEraillvmkllnvklsEiarklsRsRnCI 37 +ail + k+ +v++ E++r R +C+ FUN_000195-T1 145 ISQAILTGAKETGVSIVEVSRERFRRTQCL 174 569******************988888885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 384 (0.0150323); expected 510.9 (0.02) Passed bias filter: 379 (0.0148366); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1960.88 // Query: FUN_000196-T1 [L=146] Description: FUN_000196 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (146 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 453 (0.0177334); expected 510.9 (0.02) Passed bias filter: 351 (0.0137405); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.40s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 1527.89 // Query: FUN_000197-T1 [L=540] Description: FUN_000197 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-82 278.1 16.3 2.1e-82 277.5 16.3 1.2 1 Peptidase_A22B Signal peptide peptidase 3.7e-11 43.5 0.0 9.1e-11 42.2 0.0 1.6 1 PA PA domain ------ inclusion threshold ------ 0.041 14.4 0.3 0.13 12.7 0.0 2.0 2 RAMP4 Ribosome associated membrane protein RAMP4 5.7 7.8 7.5 2.2 9.1 0.2 2.8 3 Orf78 Orf78 (ac78) Domain annotation for each model (and alignments): >> Peptidase_A22B Signal peptide peptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 277.5 16.3 3.2e-86 2.1e-82 3 283 .. 222 502 .. 218 504 .. 0.94 Alignments for each domain: == domain 1 score: 277.5 bits; conditional E-value: 3.2e-86 Peptidase_A22B 3 keevetitkkeavlfvlvasvtlllLylffklllvllltvlfvilgvvalasllspllsrlllkkveekkvkleflkkelkaaelvvlllsivva 97 ++ + ++t ++v+fv++ + tlllL++f+++ lv++++vlf++++ ++++++l+p++ l+l +++ + l+f+k +++ ++++++s++++ FUN_000197-T1 222 EDASLEVTPWMVVIFVILICGTLLLLFYFYNY-LVYVVIVLFCLAACNGFYECLRPIVLWLPLGSCK---IPLSFIKNPPQIRIVFLVVFSLAIS 312 5667789999**********************.9*************************88666665...567777778999************* PP Peptidase_A22B 98 vlwllkrhe...wilqdilglalainvieilrlpslkvgalLLlglflYDifwVFiskylfk.tsvmvevAkgpkdaeedlPiklklPq..lsee 186 v+w ++r++ w+lqdilg++++i +i+ +rlp+lkv+++LLl l++YDif+VFi++++ +svmv+vA+ + ++e+lP++lk+P+ +s+ FUN_000197-T1 313 VWWGIERNKsyaWVLQDILGISFCISLIKNIRLPNLKVCTILLLLLLIYDIFFVFITPLFSAgKSVMVQVAT-GAGSKEQLPMVLKVPRltKSTL 406 ********99***********************************************999888*********.667899**********888889 PP Peptidase_A22B 187 aeeaskfsilGlGDivlPGllialvlrfdvskkkksketYfivtliaYglgLlvtivalalfkaaQPALLYlvPatlvtllllallrgelkklws 281 + + +++s+lG+GDi++P l i ++++fd+ +k + ++Yf++t+iaYg+gLl+t+ +l +++++QPALLYlvP+tl+t ++++ rg++k+lw+ FUN_000197-T1 407 SVCLRPYSLLGFGDILVPALYIGFCHTFDIVSKTPH-KIYFLATTIAYGMGLLITFGMLFVMEKGQPALLYLVPCTLGTGYAIGWKRGDIKRLWT 500 99****************************998886.5********************************************************9 PP Peptidase_A22B 282 ee 283 ++ FUN_000197-T1 501 GQ 502 86 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.2 0.0 1.4e-14 9.1e-11 2 91 .. 64 144 .. 63 147 .. 0.83 Alignments for each domain: == domain 1 score: 42.2 bits; conditional E-value: 1.4e-14 PA 2 tgplVaa.pndgc.easdgssedfdvkGkivLvqrGectfaeKvrnAqaaGAagviiynnvegglgapteaggeeleadpitiPavgiskad 91 ++plV a p++ c +a d + +++G v ++rG+ctf +K+ Aq+ GA+ vii++n+ +l +p+ + +++ iP + is +d FUN_000197-T1 64 KYPLVEAkPPLLCmQAQDP---S-EMSGAAVAIDRGNCTFLQKGIYAQDSGAKEVIIVSND--TLFTPD-----RNPTNNFSIPMAVISHDD 144 689**97899999655554...4.89*********************************99..766666.....3334569*******9876 PP >> RAMP4 Ribosome associated membrane protein RAMP4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.3 1.7 1.1e+04 39 47 .. 9 17 .. 8 20 .. 0.83 2 ? 12.7 0.0 2.1e-05 0.13 18 54 .. 208 246 .. 199 247 .. 0.88 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 1.7 RAMP4 39 wlLglfiFV 47 ++L+++ FV FUN_000197-T1 9 MVLVFISFV 17 7999****9 PP == domain 2 score: 12.7 bits; conditional E-value: 2.1e-05 RAMP4 18 tkrGkvpkslk..kkekkspvgpwlLglfiFVViGsaif 54 + G++++ +k ++ + v pw++++f+ ++G +++ FUN_000197-T1 208 AASGNSQNNTKqeDEDASLEVTPWMVVIFVILICGTLLL 246 67899999999877788999***************9886 PP >> Orf78 Orf78 (ac78) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 1.9 1.2e+04 58 74 .. 170 186 .. 148 188 .. 0.72 2 ? 9.1 0.2 0.00034 2.2 38 84 .. 207 250 .. 191 261 .. 0.47 3 ? 0.8 1.8 0.13 8.6e+02 67 86 .. 349 368 .. 338 374 .. 0.71 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 1.9 Orf78 58 asalnillisllavvcv 74 ++l il++ +++ v++ FUN_000197-T1 170 DGNLAILWMLAVCTVAI 186 55667888888888876 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00034 Orf78 38 ekqsvaakneieekesnaekasalnillisllavvcvlvllyviyYf 84 +++s +++n++++++++ as + +++++ v+ ++ l++++Yf FUN_000197-T1 207 NAASGNSQNNTKQEDED---ASLEVTPWMVVIFVILICGTLLLLFYF 250 33333333444444444...333444444444444444444444444 PP == domain 3 score: 0.8 bits; conditional E-value: 0.13 Orf78 67 sllavvcvlvllyviyYfvi 86 + +++ +l+l+y i++ +i FUN_000197-T1 349 KVCTILLLLLLIYDIFFVFI 368 45566677777777777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (540 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1326 (0.0519084); expected 510.9 (0.02) Passed bias filter: 673 (0.0263457); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 5284.73 // Query: FUN_000198-T1 [L=124] Description: FUN_000198 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-19 70.0 3.0 2.4e-19 69.8 3.0 1.0 1 CEP15-like Centrosomal protein 15-like ------ inclusion threshold ------ 0.019 15.2 0.4 0.022 15.0 0.4 1.2 1 YkyA Putative cell-wall binding lipoprotein 0.04 14.1 0.1 0.049 13.9 0.1 1.1 1 SPEF2_C SPEF2 C-terminal domain 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 GtgE GtgE peptidase 0.14 12.8 0.8 6.5 7.5 0.1 2.4 2 HALZ Homeobox associated leucine zipper Domain annotation for each model (and alignments): >> CEP15-like Centrosomal protein 15-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.8 3.0 4.8e-23 2.4e-19 4 99 .. 10 107 .. 7 115 .. 0.91 Alignments for each domain: == domain 1 score: 69.8 bits; conditional E-value: 4.8e-23 CEP15-like 4 ylaqEvkLskkheeilaqRalLLqqmenkledqkkkkksqleaakaAkkRNakllkdlealekslqkrlkelpk..PelvaLetrYwasveeklPk 97 la+E +Ls++heeila+R++LL+ e+ + +++ +s l+ + + RN++l+k+l+ l+ +l+k+++++ + +l+ L+ Yw +vee+ Pk FUN_000198-T1 10 WLAREAQLSQQHEEILAKREMLLAANESLMVASQQNFQSTLHGFQIIETRNDQLIKELDGLQSRLKKKTEPSFDcdAKLIGLQASYWKMVEEEFPK 105 6899**************************999999999999***************************99875116799**************** PP CEP15-like 98 We 99 W FUN_000198-T1 106 WI 107 *4 PP >> YkyA Putative cell-wall binding lipoprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.4 4.3e-06 0.022 54 115 .. 16 79 .. 8 106 .. 0.88 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 4.3e-06 YkyA 54 klseealenveeReellekekesieeakeefekieeiieei..edeelkeeaeelaeamekrye 115 +ls++ e++ +Re ll+ + + +++++f++ ++ i +++l +e++ l++ ++k++e FUN_000198-T1 16 QLSQQHEEILAKREMLLAANESLMVASQQNFQSTLHGFQIIetRNDQLIKELDGLQSRLKKKTE 79 799*******************************998887744688999999999999998875 PP >> SPEF2_C SPEF2 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.1 9.6e-06 0.049 61 114 .. 15 68 .. 5 86 .. 0.87 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 9.6e-06 SPEF2_C 61 vsllfgdselidWrkFLlaaalpwpfPsqeeLLetlkrfkevDeestglitreq 114 ++l +++e++ r+ Llaa++ + + sq++ +tl+ f+ +++++ +li++ + FUN_000198-T1 15 AQLSQQHEEILAKREMLLAANESLMVASQQNFQSTLHGFQIIETRNDQLIKELD 68 55667889999**************************************99865 PP >> GtgE GtgE peptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 2.8e-05 0.14 27 89 .. 39 108 .. 24 123 .. 0.75 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.8e-05 GtgE 27 iisnnqafnnvlegvdiiecen..llkeln.....vqkipessfftnikea.lqaeafnstiendfesfis 89 +++ +q f+ l g +iie n l+kel+ ++k e sf + k lqa ++ +e++f +i FUN_000198-T1 39 MVASQQNFQSTLHGFQIIETRNdqLIKELDglqsrLKKKTEPSFDCDAKLIgLQA-SYWKMVEEEFPKWIE 108 567899*************976559***964333367889999999999752555.566788999988876 PP >> HALZ Homeobox associated leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 0.021 1.1e+02 10 31 .. 17 38 .. 15 40 .. 0.88 2 ? 7.5 0.1 0.0013 6.5 13 42 .. 45 74 .. 43 75 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.021 HALZ 10 LKasYdsLksdfdsLkkenqkL 31 L ++++ ++ + L++ n++L FUN_000198-T1 17 LSQQHEEILAKREMLLAANESL 38 678999999***********99 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0013 HALZ 13 sYdsLksdfdsLkkenqkLkaElqeLkekl 42 ++ s + f+ +++ n++L +El L ++l FUN_000198-T1 45 NFQSTLHGFQIIETRNDQLIKELDGLQSRL 74 667777789999999********9999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1274 (0.0498728); expected 510.9 (0.02) Passed bias filter: 627 (0.0245449); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.25u 0.42s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1263.79 // Query: FUN_000198-T2 [L=94] Description: FUN_000198 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-13 48.6 1.9 1.1e-12 48.4 1.9 1.0 1 CEP15-like Centrosomal protein 15-like ------ inclusion threshold ------ 0.022 15.0 1.2 0.027 14.7 1.2 1.0 1 YkyA Putative cell-wall binding lipoprotein 0.022 15.0 0.1 0.024 14.9 0.1 1.0 1 SPEF2_C SPEF2 C-terminal domain 0.065 13.9 0.8 3.9 8.2 0.1 2.2 2 HALZ Homeobox associated leucine zipper 2.5 8.8 5.9 3.3 8.4 0.4 2.2 2 bZIP_1 bZIP transcription factor Domain annotation for each model (and alignments): >> CEP15-like Centrosomal protein 15-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.4 1.9 2.1e-16 1.1e-12 4 76 .. 10 82 .. 7 92 .. 0.92 Alignments for each domain: == domain 1 score: 48.4 bits; conditional E-value: 2.1e-16 CEP15-like 4 ylaqEvkLskkheeilaqRalLLqqmenkledqkkkkksqleaakaAkkRNakllkdlealekslqkrlkelp 76 la+E +Ls++heeila+R++LL+ e+ + +++ +s l+ + + RN++l+k+l+ l+ +l+k+++++ FUN_000198-T2 10 WLAREAQLSQQHEEILAKREMLLAANESLMVASQQNFQSTLHGFQIIETRNDQLIKELDGLQSRLKKKTEPSF 82 6899**************************999999999999**************************88765 PP >> YkyA Putative cell-wall binding lipoprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 1.2 5.3e-06 0.027 54 115 .. 16 79 .. 8 81 .. 0.90 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 5.3e-06 YkyA 54 klseealenveeReellekekesieeakeefekieeiieei..edeelkeeaeelaeamekrye 115 +ls++ e++ +Re ll+ + + +++++f++ ++ i +++l +e++ l++ ++k++e FUN_000198-T2 16 QLSQQHEEILAKREMLLAANESLMVASQQNFQSTLHGFQIIetRNDQLIKELDGLQSRLKKKTE 79 799*******************************99877774468999*******999999875 PP >> SPEF2_C SPEF2 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.1 4.6e-06 0.024 61 114 .. 15 68 .. 5 84 .. 0.87 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 4.6e-06 SPEF2_C 61 vsllfgdselidWrkFLlaaalpwpfPsqeeLLetlkrfkevDeestglitreq 114 ++l +++e++ r+ Llaa++ + + sq++ +tl+ f+ +++++ +li++ + FUN_000198-T2 15 AQLSQQHEEILAKREMLLAANESLMVASQQNFQSTLHGFQIIETRNDQLIKELD 68 56667889999**************************************99865 PP >> HALZ Homeobox associated leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.1 0.013 66 10 31 .. 17 38 .. 15 40 .. 0.88 2 ? 8.2 0.1 0.00076 3.9 13 42 .. 45 74 .. 43 75 .. 0.83 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.013 HALZ 10 LKasYdsLksdfdsLkkenqkL 31 L ++++ ++ + L++ n++L FUN_000198-T2 17 LSQQHEEILAKREMLLAANESL 38 67899999************99 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00076 HALZ 13 sYdsLksdfdsLkkenqkLkaElqeLkekl 42 ++ s + f+ +++ n++L +El L ++l FUN_000198-T2 45 NFQSTLHGFQIIETRNDQLIKELDGLQSRL 74 677777789999999*********999887 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 1.1 0.028 1.4e+02 21 57 .. 7 43 .. 5 49 .. 0.85 2 ? 8.4 0.4 0.00064 3.3 35 59 .. 53 77 .. 43 81 .. 0.86 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.028 bZIP_1 21 RqRKqaeieeLerrvkaLekeNksLkseleelkkeve 57 R + a+ ++L+++ +++ ++ ++L +e+l+ ++ FUN_000198-T2 7 RTKWLAREAQLSQQHEEILAKREMLLAANESLMVASQ 43 6777888999*************99999999976655 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00064 bZIP_1 35 vkaLekeNksLkseleelkkevekL 59 ++ +e+ N +L++el+ l+ +k+ FUN_000198-T2 53 FQIIETRNDQLIKELDGLQSRLKKK 77 57899*************9988764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (94 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1166 (0.0456449); expected 510.9 (0.02) Passed bias filter: 579 (0.0226659); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 941.34 // Query: FUN_000199-T1 [L=284] Description: FUN_000199 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.062 14.1 4.3 0.092 13.5 4.3 1.2 1 Na_trans_assoc Sodium ion transport-associated Domain annotation for each model (and alignments): >> Na_trans_assoc Sodium ion transport-associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 4.3 3.6e-06 0.092 31 159 .. 112 281 .. 97 284 .] 0.58 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 3.6e-06 Na_trans_assoc 31 kkl.........kkk.kekekelkelkkkksKlenqianhtsketkelkkake...ekkea..eeddhsdfiknpnltvsVpIA........... 99 ++l kkk +++e+ ++lk k++K e + n+ +++++lk+ + +k+ d+h++ +kn++++v I FUN_000199-T1 112 NALdllhdvvdlKKKkRAEERAKESLKAKEKKYEDYARNDLCEDPTKLKRLRVpelNKYLKhhRLDKHLKSTKNDKVKV---ITrywllqmnpeg 203 3335566666885553777777788888888888888888776666666554455544443222333444444444333...4557778888888 PP Na_trans_assoc 100 ..................egEsdlen.eeeedessesseeekskeqeqeelddssssegstvDlkdpeeelekieeeee 159 ++sd ++ e+++ sess ee+++++ + d+++s+ + + d eeele +++ ++ FUN_000199-T1 204 tdplqtslrerdeavnepLENSDNDHsDEDDNGGSESSSEEENENDYIYSGDRDESKDVILA-FIDDEEELEGQPQHVR 281 88888888888888777766677775244455556666666666566666666666655544.6667777777776655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (284 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1421 (0.0556273); expected 510.9 (0.02) Passed bias filter: 646 (0.0252887); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2840.65 // Query: FUN_000200-T1 [L=475] Description: FUN_000200 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-34 118.1 0.1 1.1e-33 115.5 0.0 2.3 3 RRM_7 RNA recognition motif 2.2e-26 92.3 8.3 2.2e-26 92.3 8.3 2.0 3 CEBP_ZZ Cytoplasmic polyadenylation element-binding 4.9e-10 39.6 0.0 4.6e-05 23.7 0.0 2.8 3 RRM_1 RNA recognition motif 0.0093 16.0 0.5 0.055 13.5 0.2 2.1 2 CEBP1_N Cytoplasmic polyadenylation element-binding ------ inclusion threshold ------ 0.016 15.8 8.6 0.03 14.9 8.6 1.5 1 ANCHR-like_BBOX ANCHR-like B-box zinc-binding domain Domain annotation for each model (and alignments): >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 2.3 1.2e+04 19 29 .. 104 114 .. 95 117 .. 0.78 2 ! 115.5 0.0 2.2e-37 1.1e-33 1 94 [] 227 320 .. 227 320 .. 0.95 3 ? -1.2 0.0 0.55 2.8e+03 2 19 .. 340 357 .. 339 371 .. 0.70 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 2.3 RRM_7 19 tatfkafGkll 29 t+tf+ fG+l+ FUN_000200-T1 104 TSTFSPFGPLS 114 689*****986 PP == domain 2 score: 115.5 bits; conditional E-value: 2.2e-37 RRM_7 1 srkvfvGGlPiDiteeeltatfkafGkllvdWPrkaeskskaaeskaakGyvflvfedeksvkaLldaceeee...gelylklssrrlkdkevqvr 93 s+kvf+GG+P+Dite+ l+++fk fG + v+WP+ka+ ++ + + kGyv+l+f++eksvkaLl +c+++ g++y+k+ssrr+++kevqv+ FUN_000200-T1 227 STKVFLGGVPWDITEASLVMSFKPFGSVRVEWPGKADGRHLHH---PPKGYVYLIFDSEKSVKALLASCTHDFcngGDWYFKISSRRMRCKEVQVI 319 79*********************************98866664...789**********************998999******************9 PP RRM_7 94 p 94 p FUN_000200-T1 320 P 320 8 PP == domain 3 score: -1.2 bits; conditional E-value: 0.55 RRM_7 2 rkvfvGGlPiDiteeelt 19 vfvGGl ++ e+l FUN_000200-T1 340 WTVFVGGLHGMLNAEGLA 357 579****98766666665 PP >> CEBP_ZZ Cytoplasmic polyadenylation element-binding protein ZZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.1 3.6 1.8e+04 30 38 .. 291 299 .. 290 311 .. 0.72 2 ? -3.0 0.0 2.4 1.2e+04 1 11 [. 314 324 .. 314 326 .. 0.84 3 ! 92.3 8.3 4.2e-30 2.2e-26 1 58 [] 412 469 .. 412 469 .. 0.99 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 3.6 CEBP_ZZ 30 aCfkYyCes 38 +C + +C+ FUN_000200-T1 291 SCTHDFCNG 299 688888874 PP == domain 2 score: -3.0 bits; conditional E-value: 2.4 CEBP_ZZ 1 KkvqvdPyled 11 K vqv P++ + FUN_000200-T1 314 KEVQVIPWVLS 324 89*****9976 PP == domain 3 score: 92.3 bits; conditional E-value: 4.2e-30 CEBP_ZZ 1 KkvqvdPyledslCseCekqqapyfCrdlaCfkYyCesCWelqHskeslkeHkplvrn 58 KkvqvdPyleds+C+ C+++++p+fCr+++CfkYyC+sCW ++Hs e +++H+pl+r+ FUN_000200-T1 412 KKVQVDPYLEDSMCDICRTTSGPFFCREESCFKYYCHSCWLWHHSIEGYRHHRPLTRT 469 9*******************************************************96 PP >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 2.9 1.5e+04 18 25 .. 106 113 .. 105 114 .. 0.84 2 ! 23.7 0.0 9e-09 4.6e-05 1 62 [. 230 295 .. 230 301 .. 0.88 3 ! 12.9 0.0 2.2e-05 0.11 1 57 [. 342 399 .. 342 405 .. 0.97 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 2.9 RRM_1 18 lFskfGpi 25 Fs+fGp FUN_000200-T1 106 TFSPFGPL 113 6*****96 PP == domain 2 score: 23.7 bits; conditional E-value: 9e-09 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd.....etgrskgfafVeFedeedaekAlealngk 62 +f+g++p+d+te +L + F++fG++ +++ + + ++ +kg+ + F++e + ++ l+++ + FUN_000200-T1 230 VFLGGVPWDITEASLVMSFKPFGSV-RVEWPGKadgrhLHHPPKGYVYLIFDSEKSVKALLASCTHD 295 89***********************.77777665588889999**************9999888765 PP == domain 3 score: 12.9 bits; conditional E-value: 2.2e-05 RRM_1 1 lfVgnLppdvteeeLkelFsk.fGpiksirlvrdetgrskgfafVeFedeedaekAle 57 +fVg+L+ ++ e L ++++ fG+++++ + +d+++ + g + ++F+++ + +A++ FUN_000200-T1 342 VFVGGLHGMLNAEGLAYIMNElFGGVVYAGIDTDKHRYPIGSGRITFNNQKSFLEAVR 399 8****************************************************99997 PP >> CEBP1_N Cytoplasmic polyadenylation element-binding protein 1 N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.1 5.1e+02 28 43 .. 11 26 .. 5 33 .. 0.86 2 ! 13.5 0.2 1.1e-05 0.055 288 307 .] 204 224 .. 98 224 .. 0.70 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.1 CEBP1_N 28 adifrrlnallgnsld 43 + i+ r+nall+ +ld FUN_000200-T1 11 TSILTRINALLDSALD 26 56999**********9 PP == domain 2 score: 13.5 bits; conditional E-value: 1.1e-05 CEBP1_N 288 vnea.tftwsGqlPprnyknP 307 n wsGqlP rnyknP FUN_000200-T1 204 CNKGnMKKWSGQLPRRNYKNP 224 44440457************9 PP >> ANCHR-like_BBOX ANCHR-like B-box zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 8.6 5.9e-06 0.03 2 38 .. 425 464 .. 424 465 .. 0.89 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 5.9e-06 ANCHR-like_BBOX 2 CdiCn.edavlrCed..CddlyCekCfkehhkkkklkdHk 38 CdiC+ ++C + C + yC +C+ hh+ ++++H+ FUN_000200-T1 425 CDICRtTSGPFFCREesCFKYYCHSCWLWHHSIEGYRHHR 464 ****8899*****753388*************999***97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (475 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 580 (0.022705); expected 510.9 (0.02) Passed bias filter: 397 (0.0155412); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4633.36 // Query: FUN_000201-T1 [L=211] Description: FUN_000201 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-15 58.4 26.6 1.6e-13 51.5 26.2 3.1 1 FoP_duplication C-terminal duplication domain of Friend of P ------ inclusion threshold ------ 0.26 11.3 0.7 27 4.9 0.1 2.2 2 KNOX2 KNOX2 domain Domain annotation for each model (and alignments): >> FoP_duplication C-terminal duplication domain of Friend of PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.5 26.2 1.2e-17 1.6e-13 5 80 .. 138 208 .. 58 209 .. 0.86 Alignments for each domain: == domain 1 score: 51.5 bits; conditional E-value: 1.2e-17 FoP_duplication 5 raakrrkgsrggrrgrgrggrggrrgrgrgrggrrkrkkkkpktkeeLDaeLDeYmgpktkkskLDaeLDsYmkkk 80 r++ + ++s +g +++ rg+rggr gr rg++r+ +kp++k+ LDaeLD+Ym+ kt ks+LDaeLD+Ym+ + FUN_000201-T1 138 RGNVGVGRSGRGLQRAKRGARGGRVGRVATRGRGRG---DKPVSKDKLDAELDQYMS-KT-KSHLDAELDEYMQHA 208 333333333444455567777777777777777777...******************.**.************976 PP >> KNOX2 KNOX2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.0021 27 4 13 .. 182 191 .. 179 192 .. 0.84 2 ? 4.8 0.1 0.0022 28 3 13 .. 196 206 .. 194 207 .. 0.85 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0021 KNOX2 4 adpELDqFMe 13 d ELDq+M+ FUN_000201-T1 182 LDAELDQYMS 191 699******7 PP == domain 2 score: 4.8 bits; conditional E-value: 0.0022 KNOX2 3 gadpELDqFMe 13 + d ELD++M+ FUN_000201-T1 196 HLDAELDEYMQ 206 679*******7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 897 (0.0351145); expected 510.9 (0.02) Passed bias filter: 644 (0.0252104); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2092.99 // Query: FUN_000202-T1 [L=489] Description: FUN_000202 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-76 257.6 0.0 1.7e-76 257.1 0.0 1.2 1 Lectin_leg-like Legume-like lectin family ------ inclusion threshold ------ 1.8 9.1 12.1 3.6 8.1 0.6 2.3 2 DUF1664 Protein of unknown function (DUF1664) 5.8 7.8 15.2 0.17 12.7 5.0 2.9 2 BLOC1_2 Biogenesis of lysosome-related organelles co Domain annotation for each model (and alignments): >> Lectin_leg-like Legume-like lectin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 257.1 0.0 2e-80 1.7e-76 2 228 .. 31 253 .. 30 255 .. 0.98 Alignments for each domain: == domain 1 score: 257.1 bits; conditional E-value: 2e-80 Lectin_leg-like 2 afkrehslkkPylgqgskalpeWeyggsaildsnqirltsdeqskkGslwtkspvaleswevevsFrvtgsetelegdglaiwytsergkegpv 95 +f+++hs+k P+l+++++++p+W++ggsai +++qirlt++ +kkG lwtks + ++wevev +vtg ++l+gdg+aiwyt+ g egp FUN_000202-T1 31 KFQYKHSFKGPHLANKEGSIPFWAHGGSAIPSDDQIRLTPSMTNKKGYLWTKSGFPHDWWEVEVAIKVTGV-GRLGGDGVAIWYTETAGIEGPA 123 589********************************************************************.99******************** PP Lectin_leg-like 96 FgskdkfdGlailldtydndngpdkknkpaisamlndgsleydhekdgkaqelasCtadfrnkdyetlikikYdknaltvlidsgllenkndyk 189 Fg + ++Gl+i+ d++dnd+ + n+p+is+mlndg+ ydh+kdg++ + ++C++dfrn++ ++++ki+Y++n+lt+ ++ g++ + +d++ FUN_000202-T1 124 FGNVNTWKGLGIFCDSFDNDQ---QGNNPFISVMLNDGTHIYDHNKDGQDLQRGGCLRDFRNRPNPVKLKIRYYENVLTLWVHMGMSMKAEDFE 214 *********************...558******************************************************************* PP Lectin_leg-like 190 lCfqvkevelPtgyyfgvsaatgdlsdnhdvlsllllql 228 lC +++++ l +g+yfg+saatg+l+d+hdv+s+ + +l FUN_000202-T1 215 LCTRLENIALGKGGYFGLSAATGGLADDHDVISFITHSL 253 **********************************99876 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.6 0.00042 3.6 44 120 .. 272 346 .. 263 349 .. 0.84 2 ? 4.9 5.3 0.0044 37 63 124 .] 374 435 .. 354 435 .. 0.78 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.00042 DUF1664 44 esvskqleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklkei 120 ++++q e+ +++l+++++e++ ++ +k+ + ++ ++ +++v v e+ ++i++ + ++++ v +l +++++ FUN_000202-T1 272 RKLAEQYEEYQKKLEQQREEFKT--AHPEKTKQPEAQYENAYERDVRLVYEGQNAIHQMIGNLHNKVGELTLQINTL 346 56888999999999999999976..5677777777888899999************************999999876 PP == domain 2 score: 4.9 bits; conditional E-value: 0.0044 DUF1664 63 eLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklkeieekQ 124 L + +++ +kl+e++++ ++ + v + + ++++++++++ +e+l +++++ ++kQ FUN_000202-T1 374 TLINVQQQLVAKLQEMSNMMNQGGNVVKRDTGESAVTNTQLSNMQKSIESLTESVNHFSTKQ 435 45555577888999999999998888888888888999999999999999999999998888 PP >> BLOC1_2 Biogenesis of lysosome-related organelles complex-1 subunit 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 2.5 0.35 3e+03 57 57 .. 289 289 .. 263 350 .. 0.63 2 ? 12.7 5.0 2e-05 0.17 4 83 .. 354 430 .. 351 434 .. 0.82 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.35 BLOC1_2 57 y 57 FUN_000202-T1 289 R 289 2 PP == domain 2 score: 12.7 bits; conditional E-value: 2e-05 BLOC1_2 4 ftkvskyveaeleataedlklLeklNeatsekykklkdvasslekeleelkekyeelqpylqqidqieeqvtkLeetvke 83 ++k++++v+ + +++++++++L ++ ++ +k +++++++++ + + k+ e + +q+ ++++++++L+e v++ FUN_000202-T1 354 HNKLNNVVTVDQTISRQEVNTLINVQQQLVAKLQEMSNMMNQGGNVV---KRDTGESAVTNTQLSNMQKSIESLTESVNH 430 58999********************9999999999999988755544...444558888888888888888888888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (489 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2826 (0.110628); expected 510.9 (0.02) Passed bias filter: 1151 (0.0450577); expected 510.9 (0.02) Passed Vit filter: 109 (0.00426698); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.42s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 4663.28 // Query: FUN_000203-T1 [L=224] Description: FUN_000203 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00023 21.3 0.0 0.0004 20.5 0.0 1.4 1 RIIa Regulatory subunit of type II PKA R-subunit Domain annotation for each model (and alignments): >> RIIa Regulatory subunit of type II PKA R-subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 1.5e-08 0.0004 3 34 .. 20 51 .. 18 54 .. 0.90 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 1.5e-08 RIIa 3 lqaLLedltveVlraqPsDvlqFaadYFekLe 34 l ++L+ +t + r+qP Dvlq a++YF+ L FUN_000203-T1 20 LPDVLKQFTKAAIRTQPKDVLQWAYAYFDALS 51 6689************************9775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 509 (0.0199256); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2246.05 // Query: FUN_000204-T1 [L=496] Description: FUN_000204 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-18 65.0 15.6 6.4e-06 26.8 0.0 5.8 6 TPR_12 Tetratricopeptide repeat 4.3e-08 33.2 9.1 0.048 14.3 0.1 5.8 5 TPR_2 Tetratricopeptide repeat 2.3e-07 30.8 2.6 0.29 11.5 0.0 4.1 3 TPR_1 Tetratricopeptide repeat 3.1e-07 30.7 9.3 4.5 7.9 0.0 6.5 6 TPR_10 Tetratricopeptide repeat 2.7e-06 27.6 12.2 0.2 12.4 0.1 5.9 5 TPR_8 Tetratricopeptide repeat 0.0019 18.5 3.3 0.11 12.9 0.2 3.3 3 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR dom 0.0028 18.1 0.3 6.9 7.5 0.0 3.7 2 TPR_7 Tetratricopeptide repeat ------ inclusion threshold ------ 0.023 14.9 0.8 61 3.9 0.1 3.8 3 TPR_11 TPR repeat 0.046 12.4 0.0 0.063 11.9 0.0 1.1 1 P1 Major inner capsid protein P1 0.053 14.5 7.5 2.4 9.2 0.2 3.8 3 TPR_16 Tetratricopeptide repeat 0.073 12.9 5.7 4.9 7.0 0.9 3.5 3 TPR_NPHP3 Nephrocystin-3 TPR domain 0.18 13.1 11.8 8 8.0 0.1 5.8 6 TPR_14 Tetratricopeptide repeat 0.19 12.5 3.6 2.9 8.9 0.0 3.9 4 TPR_17 Tetratricopeptide repeat 0.23 12.3 0.1 6.8 7.6 0.1 2.5 2 HTHP Hexameric tyrosine-coordinated heme protein (H 0.29 11.6 9.1 3.6 8.0 1.7 3.5 3 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.44 11.1 1.9 0.8 10.3 0.8 2.0 2 MAS20 MAS20 protein import receptor Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 1.0 2.8e-05 0.044 18 74 .. 104 160 .. 92 163 .. 0.89 2 ? 4.5 0.0 0.035 56 48 71 .. 188 211 .. 181 223 .. 0.81 3 ! 18.6 0.3 1.4e-06 0.0022 8 60 .. 237 289 .. 230 292 .. 0.87 4 ! 7.3 0.1 0.0048 7.7 19 74 .. 293 349 .. 290 352 .. 0.89 5 ! 8.1 0.0 0.0026 4.2 20 71 .. 337 388 .. 317 392 .. 0.92 6 ! 26.8 0.0 4e-09 6.4e-06 8 75 .. 367 434 .. 360 435 .. 0.92 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 2.8e-05 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylal.gdyeeAlelleqalei 74 + + A + + ++++l + l+G++h +a a+ L+++yl++ g e+Al + e a ++ FUN_000204-T1 104 D-ERAVSDCVRCVALSRILHGDNHWKLAKAHSKLSQAYLEQgGMAEQALLHAENARNV 160 5.778999999***************************9888999***9999988765 PP == domain 2 score: 4.5 bits; conditional E-value: 0.035 TPR_12 48 lrnLgrlylalgdyeeAlelleqa 71 + +g ++lal+++ +A++ l++a FUN_000204-T1 188 YLVMGKAQLALKNTHKAEQNLKKA 211 667788888888888888888887 PP == domain 3 score: 18.6 bits; conditional E-value: 1.4e-06 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgd 60 l+ +++r+ + Ale +ekal++ ++ +G+d+ +++ +++ L+ + + +g+ FUN_000204-T1 237 SLGRACLRANKSGHALEAFEKALQITQAQYGDDSAELIPIYQCLAKAESSQGN 289 57888888888888********************************9999998 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0048 TPR_12 19 ydeAlellekalelaerllGpdhpltatalrnLgrlyl.algdyeeAlelleqalei 74 ++ A + l +a+e+ ++ +G+d+ + a++ + ++ y ++A ++le+++++ FUN_000204-T1 293 HERATQVLLQAHEISRARYGEDSIEFAESSFVVATSYInSFDGDAKAKNYLEDVVRL 349 78899999**************************99976889999999999998775 PP == domain 5 score: 8.1 bits; conditional E-value: 0.0026 TPR_12 20 deAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqa 71 ++A +le +++l + +Gp+h t+ a+ L+rl+ + g +eeA++l + + FUN_000204-T1 337 AKAKNYLEDVVRLNMQHRGPYHSSTIKAQDELSRLLVRGGFLEEAVSLQKSV 388 689999********9999***************************9998865 PP == domain 6 score: 26.8 bits; conditional E-value: 4e-09 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +l +l r g ++eA +l++ + ++ l+G+ + + a +++ Lg + l++g++++Al++l + ++++ FUN_000204-T1 367 ELSRLLVRGGFLEEAVSLQKSVADAKVVLYGDPSQEAADCYQMLGSIRLKQGRLQQALKWLTKGYNML 434 6777888999*****************************************************99986 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.23 3.6e+02 1 15 [. 130 144 .. 130 144 .. 0.94 2 ? 4.7 0.1 0.036 58 4 28 .. 188 212 .. 186 217 .. 0.86 3 ! 14.3 0.1 3e-05 0.048 6 30 .. 237 261 .. 233 264 .. 0.92 4 ? -0.3 0.0 1.4 2.2e+03 18 33 .. 337 352 .. 336 353 .. 0.87 5 ! 12.2 0.1 0.00014 0.23 1 26 [. 404 429 .. 404 433 .. 0.92 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.23 TPR_2 1 aealynlGlayyklg 15 a+a+ l++ay+++g FUN_000204-T1 130 AKAHSKLSQAYLEQG 144 799**********98 PP == domain 2 score: 4.7 bits; conditional E-value: 0.036 TPR_2 4 lynlGlayyklgdyeeAleayekAl 28 + +G+a ++l++ +A++ ++kA FUN_000204-T1 188 YLVMGKAQLALKNTHKAEQNLKKAE 212 66789*****************995 PP == domain 3 score: 14.3 bits; conditional E-value: 3e-05 TPR_2 6 nlGlayyklgdyeeAleayekAlel 30 lG+a++++++ Alea+ekAl++ FUN_000204-T1 237 SLGRACLRANKSGHALEAFEKALQI 261 59*********************98 PP == domain 4 score: -0.3 bits; conditional E-value: 1.4 TPR_2 18 eeAleayekAleldPn 33 ++A++++e +++l+ + FUN_000204-T1 337 AKAKNYLEDVVRLNMQ 352 69**********9976 PP == domain 5 score: 12.2 bits; conditional E-value: 0.00014 TPR_2 1 aealynlGlayyklgdyeeAleayek 26 a+++ +lG + +k+g++++Al+++ k FUN_000204-T1 404 ADCYQMLGSIRLKQGRLQQALKWLTK 429 68999******************988 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.0 0.1 0.0097 15 4 27 .. 188 211 .. 186 215 .. 0.91 2 ! 11.5 0.0 0.00018 0.29 6 30 .. 237 261 .. 234 261 .. 0.93 3 ! 10.4 0.0 0.00042 0.67 1 26 [. 404 429 .. 404 430 .. 0.91 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0097 TPR_1 4 lynlGnayfklgkydeAleyyekA 27 + +G a ++l++ +A++ +kA FUN_000204-T1 188 YLVMGKAQLALKNTHKAEQNLKKA 211 67799*****************99 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00018 TPR_1 6 nlGnayfklgkydeAleyyekALel 30 lG a+++ +k Ale++ekAL++ FUN_000204-T1 237 SLGRACLRANKSGHALEAFEKALQI 261 5999*******************97 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00042 TPR_1 1 akalynlGnayfklgkydeAleyyek 26 a+++ lG + +k+g++++Al+ k FUN_000204-T1 404 ADCYQMLGSIRLKQGRLQQALKWLTK 429 789999***************98876 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0038 6 19 40 .. 105 126 .. 104 128 .. 0.94 2 ! 6.8 0.2 0.0064 10 8 40 .. 238 270 .. 225 272 .. 0.84 3 ? 4.3 0.2 0.037 59 18 41 .. 293 316 .. 276 317 .. 0.81 4 ? -2.9 0.0 7 1.1e+04 21 31 .. 339 349 .. 337 350 .. 0.83 5 ? 4.3 0.0 0.037 60 1 37 [. 361 397 .. 361 402 .. 0.80 6 ! 7.9 0.0 0.0028 4.5 2 40 .. 404 442 .. 403 442 .. 0.91 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0038 TPR_10 19 eeAeelleealairervlGpdH 40 e+A+ ++ +++a+ + ++G++H FUN_000204-T1 105 ERAVSDCVRCVALSRILHGDNH 126 6899****************** PP == domain 2 score: 6.8 bits; conditional E-value: 0.0064 TPR_10 8 LanalraqgryeeAeelleealairervlGpdH 40 L++a + ++ A+e +e+al+i+++ +G+d+ FUN_000204-T1 238 LGRACLRANKSGHALEAFEKALQITQAQYGDDS 270 5556666667778*************9999997 PP == domain 3 score: 4.3 bits; conditional E-value: 0.037 TPR_10 18 yeeAeelleealairervlGpdHP 41 +e+A + l +a +i ++ +G+d+ FUN_000204-T1 293 HERATQVLLQAHEISRARYGEDSI 316 689******************986 PP == domain 4 score: -2.9 bits; conditional E-value: 7 TPR_10 21 Aeelleealai 31 A ++le+++++ FUN_000204-T1 339 AKNYLEDVVRL 349 899****9985 PP == domain 5 score: 4.3 bits; conditional E-value: 0.037 TPR_10 1 tasslnnLanalraqgryeeAeelleealairervlG 37 t+ + + L+++l + g +eeA+ l++ + + ++G FUN_000204-T1 361 TIKAQDELSRLLVRGGFLEEAVSLQKSVADAKVVLYG 397 5667889*****************8887776666666 PP == domain 6 score: 7.9 bits; conditional E-value: 0.0028 TPR_10 2 asslnnLanalraqgryeeAeelleealairervlGpdH 40 a+++ L+ + +qgr++ A+++l + + +lG H FUN_000204-T1 404 ADCYQMLGSIRLKQGRLQQALKWLTKGYNMLTVTLGTSH 442 899*********************999888888888887 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.1 2.1 3.3e+03 1 15 [. 130 144 .. 130 150 .. 0.78 2 ! 7.5 0.3 0.0047 7.5 3 27 .. 187 211 .. 186 215 .. 0.95 3 ! 9.5 0.1 0.001 1.7 5 32 .. 236 263 .. 232 265 .. 0.88 4 ? 1.3 0.0 0.44 7.1e+02 19 31 .. 338 350 .. 336 353 .. 0.89 5 ! 12.4 0.1 0.00012 0.2 1 27 [. 404 430 .. 404 433 .. 0.91 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 2.1 TPR_8 1 aeayynlGliylklg 15 a+a+ +l+++yl++g FUN_000204-T1 130 AKAHSKLSQAYLEQG 144 577788999998887 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0047 TPR_8 3 ayynlGliylklgdyeeAkeyyeka 27 +y+ +G++ l l++ ++A++ ++ka FUN_000204-T1 187 IYLVMGKAQLALKNTHKAEQNLKKA 211 6999********************8 PP == domain 3 score: 9.5 bits; conditional E-value: 0.001 TPR_8 5 ynlGliylklgdyeeAkeyyekaleldp 32 + lG+++l+ ++ A e++ekal++ + FUN_000204-T1 236 MSLGRACLRANKSGHALEAFEKALQITQ 263 679*********************9975 PP == domain 4 score: 1.3 bits; conditional E-value: 0.44 TPR_8 19 eAkeyyekaleld 31 +Ak+y+e +++l+ FUN_000204-T1 338 KAKNYLEDVVRLN 350 8*********997 PP == domain 5 score: 12.4 bits; conditional E-value: 0.00012 TPR_8 1 aeayynlGliylklgdyeeAkeyyeka 27 a+ y++lG+i lk+g++++A +++ k FUN_000204-T1 404 ADCYQMLGSIRLKQGRLQQALKWLTKG 430 689********************9985 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.13 2e+02 54 83 .. 189 218 .. 187 230 .. 0.88 2 ! 12.9 0.2 6.7e-05 0.11 54 104 .. 236 290 .. 234 310 .. 0.66 3 ? 1.8 0.0 0.16 2.6e+02 53 79 .. 407 433 .. 395 437 .. 0.81 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.13 TPR_CcmH_CycH 54 llLGriglslndaetAiqAfekAlklapnn 83 l++G+ +l+l+++++A q ++kA l++++ FUN_000204-T1 189 LVMGKAQLALKNTHKAEQNLKKAEILSQER 218 6799*******************9888876 PP == domain 2 score: 12.9 bits; conditional E-value: 6.7e-05 TPR_CcmH_CycH 54 llLGriglslndaetAiqAfekAlklap....nnteiklsYaqaLmlsgdeedlk 104 + LGr l n+ A++AfekAl++++ ++++ + q L ++ + ++ FUN_000204-T1 236 MSLGRACLRANKSGHALEAFEKALQITQaqygDDSAELIPIYQCLAKAESSQGNA 290 67************************97222223344444455555554444444 PP == domain 3 score: 1.8 bits; conditional E-value: 0.16 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlkl 79 +LG i l+++++++A++ + k +++ FUN_000204-T1 407 YQMLGSIRLKQGRLQQALKWLTKGYNM 433 569999999999999999988888875 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.1 0.011 18 4 30 .. 237 263 .. 236 265 .. 0.92 2 ! 7.5 0.0 0.0043 6.9 4 24 .. 409 429 .. 406 430 .. 0.91 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.011 TPR_7 4 aLariyrklGdydeAirlyerlLalak 30 +L+r++ + ++ A++ +e++L++++ FUN_000204-T1 237 SLGRACLRANKSGHALEAFEKALQITQ 263 69********************99875 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0043 TPR_7 4 aLariyrklGdydeAirlyer 24 L++i k+G+ ++A++++++ FUN_000204-T1 409 MLGSIRLKQGRLQQALKWLTK 429 79***************9986 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.064 1e+02 28 42 .] 130 144 .. 128 144 .. 0.92 2 ? 3.9 0.1 0.038 61 1 25 [. 239 263 .. 239 265 .. 0.78 3 ? 3.6 0.0 0.047 76 1 17 [. 411 427 .. 411 430 .. 0.88 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.064 TPR_11 28 aeayynLGlayykqG 42 a a+++L +ay++qG FUN_000204-T1 130 AKAHSKLSQAYLEQG 144 89************9 PP == domain 2 score: 3.9 bits; conditional E-value: 0.038 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldP 25 G+a+ +k A+ea++kAl++++ FUN_000204-T1 239 GRACLRANKSGHALEAFEKALQITQ 263 566666677778***********87 PP == domain 3 score: 3.6 bits; conditional E-value: 0.047 TPR_11 1 GdayyeqGkyeeAieaY 17 G + +qG++ +A++++ FUN_000204-T1 411 GSIRLKQGRLQQALKWL 427 78899*********987 PP >> P1 Major inner capsid protein P1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 4e-05 0.063 171 244 .. 99 181 .. 81 196 .. 0.78 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 4e-05 P1 171 iatfpdyralvDavraseLrRvle.....eLedaDvklvkaqfkk....kaAlapaliarelaaaataAseraRGsydaiavv 244 + + d ra+ D+vr L R+l+ +L++a +kl +a +++ Al a ar++ aa++A+++ R yd +v FUN_000204-T1 99 FKSMGDERAVSDCVRCVALSRILHgdnhwKLAKAHSKLSQAYLEQggmaEQALLHAENARNVLLAADTAKQQGRQVYDRSDVL 181 45566779***************7555557***********9987211144666666799*******************9995 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.8 1.2 1.9e+03 33 51 .. 132 150 .. 128 171 .. 0.62 2 ? 9.2 0.2 0.0015 2.4 30 61 .. 231 262 .. 189 267 .. 0.81 3 ? 6.8 0.0 0.0085 14 5 55 .. 370 428 .. 367 431 .. 0.73 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.2 TPR_16 33 AllglGlallrqgrlaeAa 51 A+ l +a+l+qg +ae a FUN_000204-T1 132 AHSKLSQAYLEQGGMAEQA 150 5555666666666555554 PP == domain 2 score: 9.2 bits; conditional E-value: 0.0015 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraalraa 61 ++++ lG+a+lr+++ A++a+++al++ FUN_000204-T1 231 RLEISMSLGRACLRANKSGHALEAFEKALQIT 262 557899**********************9765 PP == domain 3 score: 6.8 bits; conditional E-value: 0.0085 TPR_16 5 raalaagdyddAaaaleaalrrn........PeaaaAllglGlallrqgrlaeAaaayr 55 r++++ g ++A+ + + ++++ eaa+ + lG + l+qgrl+ A++++ FUN_000204-T1 370 RLLVRGGFLEEAVSLQKSVADAKvvlygdpsQEAADCYQMLGSIRLKQGRLQQALKWLT 428 6666667777777555555555577777777778888889***************9985 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.1 0.23 3.6e+02 63 107 .. 126 172 .. 113 181 .. 0.67 2 ? 7.0 0.9 0.0031 4.9 106 209 .. 239 303 .. 165 322 .. 0.56 3 ? 4.7 0.0 0.015 24 93 127 .. 398 432 .. 381 447 .. 0.83 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.23 TPR_NPHP3 63 yWqyvgadksklakaYlnaikkledav...egeltlakvadlyealGr 107 +W++ ++ +skl++aYl++ + e+a+ e+ +++ ad+ + Gr FUN_000204-T1 126 HWKL-AKAHSKLSQAYLEQGGMAEQALlhaENARNVLLAADTAKQQGR 172 4654.4556788888888888888776443444455555777777776 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0031 TPR_NPHP3 106 GrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkq...dk 198 Gr + + a + +++al+i++ +yG d ++ ++ la q FUN_000204-T1 239 GRACLRANKSG------------------------------------------HALEAFEKALQITQAQYGDDSAELIPIYQCLAKAESSQgnaSS 292 44444444444..........................................4555556666666666666665555555555543322211112 PP TPR_NPHP3 199 hdlaeplkkra 209 h+ a ++ +a FUN_000204-T1 293 HERATQVLLQA 303 22222222222 PP == domain 3 score: 4.7 bits; conditional E-value: 0.015 TPR_NPHP3 93 ltlakvadlyealGrflkdlgllsqalpaLqraLe 127 +++++ ad y++lG + g l+qal+ L + + FUN_000204-T1 398 DPSQEAADCYQMLGSIRLKQGRLQQALKWLTKGYN 432 567889**********************9998765 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.2 7.1 1.1e+04 11 27 .. 141 157 .. 131 167 .. 0.62 2 ? 2.5 0.1 0.31 4.9e+02 4 27 .. 188 211 .. 186 221 .. 0.86 3 ? 8.0 0.1 0.005 8 3 30 .. 234 261 .. 232 271 .. 0.87 4 ? -1.0 0.0 4 6.3e+03 4 27 .. 277 303 .. 275 310 .. 0.61 5 ? -1.1 0.0 4.3 6.9e+03 3 22 .. 364 383 .. 362 384 .. 0.83 6 ? 5.3 0.0 0.039 62 2 26 .. 405 429 .. 404 433 .. 0.89 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 7.1 TPR_14 11 llalGdpdeAlellera 27 l++ G ++Al ++e a FUN_000204-T1 141 LEQGGMAEQALLHAENA 157 34444666666665555 PP == domain 2 score: 2.5 bits; conditional E-value: 0.31 TPR_14 4 wlalarallalGdpdeAlellera 27 +l +++a lal+++++A++ l++a FUN_000204-T1 188 YLVMGKAQLALKNTHKAEQNLKKA 211 7889999999*******9999988 PP == domain 3 score: 8.0 bits; conditional E-value: 0.005 TPR_14 3 awlalarallalGdpdeAlelleralal 30 + + l+ra+l++++ Ale++e+al+ FUN_000204-T1 234 ISMSLGRACLRANKSGHALEAFEKALQI 261 56789********************985 PP == domain 4 score: -1.0 bits; conditional E-value: 4 TPR_14 4 wlalarallalGd...pdeAlellera 27 ++ la+a+ +G+ +++A ++l +a FUN_000204-T1 277 YQCLAKAESSQGNassHERATQVLLQA 303 667888888888733344455554444 PP == domain 5 score: -1.1 bits; conditional E-value: 4.3 TPR_14 3 awlalarallalGdpdeAle 22 a+ l r+l++ G ++eA+ FUN_000204-T1 364 AQDELSRLLVRGGFLEEAVS 383 77889999999999999986 PP == domain 6 score: 5.3 bits; conditional E-value: 0.039 TPR_14 2 eawlalarallalGdpdeAleller 26 +++++l+ + l++G++++Al+ l + FUN_000204-T1 405 DCYQMLGSIRLKQGRLQQALKWLTK 429 67999****************9976 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.1 0.45 7.2e+02 9 27 .. 126 144 .. 124 151 .. 0.76 2 ? -0.8 0.1 2.2 3.5e+03 15 34 .] 187 206 .. 186 206 .. 0.84 3 ? -2.1 0.0 5.8 9.2e+03 15 28 .. 276 289 .. 274 292 .. 0.84 4 ? 8.9 0.0 0.0018 2.9 13 33 .. 404 424 .. 398 425 .. 0.92 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.45 TPR_17 9 dPnnadayynLArlllnnG 27 +++ a+a+ L +++l++G FUN_000204-T1 126 HWKLAKAHSKLSQAYLEQG 144 567789999*******997 PP == domain 2 score: -0.8 bits; conditional E-value: 2.2 TPR_17 15 ayynLArlllnnGqleeAlq 34 +y ++ ++l ++++ +A+q FUN_000204-T1 187 IYLVMGKAQLALKNTHKAEQ 206 57778999999999999987 PP == domain 3 score: -2.1 bits; conditional E-value: 5.8 TPR_17 15 ayynLArlllnnGq 28 +y++LA + + +G+ FUN_000204-T1 276 IYQCLAKAESSQGN 289 7999**99998887 PP == domain 4 score: 8.9 bits; conditional E-value: 0.0018 TPR_17 13 adayynLArlllnnGqleeAl 33 ad+y++L+ + l++G+l++Al FUN_000204-T1 404 ADCYQMLGSIRLKQGRLQQAL 424 799*****************8 PP >> HTHP Hexameric tyrosine-coordinated heme protein (HTHP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.24 3.9e+02 36 58 .. 259 281 .. 232 286 .. 0.83 2 ? 7.6 0.1 0.0043 6.8 29 61 .. 297 329 .. 290 344 .. 0.76 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.24 HTHP 36 rkklReeYaeDaasLiavsqvvA 58 ++ ++Y +D+a+Li + q +A FUN_000204-T1 259 LQITQAQYGDDSAELIPIYQCLA 281 5556789*********9998877 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0043 HTHP 29 tqpdaevrkklReeYaeDaasLiavsqvvAveF 61 tq + + R++Y eD+ + ++s vvA+++ FUN_000204-T1 297 TQVLLQAHEISRARYGEDSIEFAESSFVVATSY 329 66666777788*******************974 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 1.7 0.0023 3.6 10 86 .. 188 261 .. 184 266 .. 0.85 2 ? 4.0 0.5 0.038 61 14 106 .. 239 326 .. 227 333 .. 0.69 3 ? 5.0 0.0 0.019 31 14 51 .. 411 448 .. 403 476 .. 0.77 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0023 ARM_TT21 10 hlikakvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee 86 +l+ +k++ + +++++A + Lk+A l+++++ + + + + + ++++ ++l +++ +++k+ A +++++a++ FUN_000204-T1 188 YLVMGKAQLALKNTHKAEQNLKKAEILSQEREGRGYS---HQAMQRRLEISMSLGRACLRANKSGHALEAFEKALQI 261 6899999******************998876665544...445678999***********************99875 PP == domain 2 score: 4.0 bits; conditional E-value: 0.038 ARM_TT21 14 akvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkve...eAkkllqeaieefkgtpeevrillanaelala 106 ++++ +++k +Al+++++Al++++ + + + + + +y l+++ s++++++ A+++l +a e + e+ i +a++++ +a FUN_000204-T1 239 GRACLRANKSGHALEAFEKALQITQAQYGDD--------SAELIPIYQCLAKAESSQGNASsheRATQVLLQAHEISRARYGEDSIEFAESSFVVA 326 6677788888999999999999976543333........235667777777776655444322268888888888888888888888887777666 PP == domain 3 score: 5.0 bits; conditional E-value: 0.019 ARM_TT21 14 akvlkkegkleeAlktLktAlklpgkkkskekkkekes 51 +++ k+g+l++Alk L++ +++ + + +++k++k++ FUN_000204-T1 411 GSIRLKQGRLQQALKWLTKGYNMLTVTLGTSHKRTKQM 448 677889****************9987766666665544 PP >> MAS20 MAS20 protein import receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 3.8 6.1e+03 56 91 .. 118 153 .. 90 164 .. 0.60 2 ? 10.3 0.8 0.0005 0.8 42 119 .. 200 278 .. 191 287 .. 0.69 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 3.8 MAS20 56 kealeeakeeplptdaeekeayFleevqlGEellaq 91 +++l+ +++ +l + ++++ + +le+ + E+ l + FUN_000204-T1 118 SRILHGDNHWKLAKAHSKLSQAYLEQGGMAEQALLH 153 445555555566677777777777777777776655 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0005 MAS20 42 eeaeaekkkkkeaikealeeakeeplptdaeekeayFleevqlGEellaqgdeeeaalhlykAlkvypq.....PkeLlqilq 119 + ++k++++ + e+l+ +++e+ +++++++ +++lG ++l +++ +a++++ kAl++ + +eL+ i+q FUN_000204-T1 200 N---THKAEQNLKKAEILS-QEREGRGYSHQAMQRRLEISMSLGRACLRANKSGHALEAFEKALQITQAqygddSAELIPIYQ 278 2...222233332323333.34456668999**********************************976411112466777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (496 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 926 (0.0362498); expected 510.9 (0.02) Passed bias filter: 625 (0.0244666); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 4845.65 // Query: FUN_000204-T2 [L=463] Description: FUN_000204 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-18 65.6 15.6 5.8e-06 26.9 0.0 5.7 6 TPR_12 Tetratricopeptide repeat 2.8e-08 33.8 9.1 0.044 14.4 0.1 5.8 5 TPR_2 Tetratricopeptide repeat 1e-07 32.2 8.5 4.1 8.0 0.0 6.6 7 TPR_10 Tetratricopeptide repeat 1.7e-07 31.3 2.6 0.27 11.6 0.0 4.2 3 TPR_1 Tetratricopeptide repeat 1.7e-06 28.2 12.2 0.18 12.5 0.1 6.0 5 TPR_8 Tetratricopeptide repeat 0.0015 18.9 3.3 0.097 13.0 0.2 3.3 3 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR dom 0.0022 18.4 0.3 6.3 7.7 0.0 3.7 2 TPR_7 Tetratricopeptide repeat ------ inclusion threshold ------ 0.018 15.2 0.8 56 4.0 0.1 3.8 3 TPR_11 TPR repeat 0.041 12.5 0.0 0.057 12.1 0.0 1.1 1 P1 Major inner capsid protein P1 0.046 14.7 7.5 2.2 9.3 0.2 3.8 3 TPR_16 Tetratricopeptide repeat 0.11 13.8 11.6 7.4 8.1 0.1 5.8 6 TPR_14 Tetratricopeptide repeat 0.12 12.8 8.0 2.6 8.5 1.9 3.5 4 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.18 12.7 3.8 2.7 9.0 0.0 3.9 4 TPR_17 Tetratricopeptide repeat 0.2 12.6 0.1 6.2 7.7 0.1 2.5 2 HTHP Hexameric tyrosine-coordinated heme protein (H 0.29 11.7 1.5 0.62 10.6 0.6 2.0 2 MAS20 MAS20 protein import receptor Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.9 2.1e-05 0.036 17 74 .. 103 160 .. 91 163 .. 0.89 2 ? 4.6 0.0 0.03 51 48 71 .. 188 211 .. 181 223 .. 0.81 3 ! 18.8 0.3 1.2e-06 0.002 8 60 .. 237 289 .. 230 292 .. 0.87 4 ! 7.4 0.1 0.0041 7 19 74 .. 293 349 .. 290 352 .. 0.89 5 ! 8.0 0.0 0.0027 4.6 20 71 .. 337 388 .. 334 392 .. 0.91 6 ! 26.9 0.0 3.4e-09 5.8e-06 8 75 .. 367 434 .. 360 435 .. 0.92 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.1e-05 TPR_12 17 grydeAlellekalelaerllGpdhpltatalrnLgrlylal.gdyeeAlelleqalei 74 g+ + A + + ++++l + l+G++h +a a+ L+++yl++ g e+Al + e a ++ FUN_000204-T2 103 GD-ERAVSDCVRCVALSRILHGDNHWKLAKAHSKLSQAYLEQgGMAEQALLHAENARNV 160 55.77899999****************************9888999***9999988765 PP == domain 2 score: 4.6 bits; conditional E-value: 0.03 TPR_12 48 lrnLgrlylalgdyeeAlelleqa 71 + +g ++lal+++ +A++ l++a FUN_000204-T2 188 YLVMGKAQLALKNTHKAEQNLKKA 211 667788888888888888888887 PP == domain 3 score: 18.8 bits; conditional E-value: 1.2e-06 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgd 60 l+ +++r+ + Ale +ekal++ ++ +G+d+ +++ +++ L+ + + +g+ FUN_000204-T2 237 SLGRACLRANKSGHALEAFEKALQITQAQYGDDSAELIPIYQCLAKAESSQGN 289 57888888888888********************************9999998 PP == domain 4 score: 7.4 bits; conditional E-value: 0.0041 TPR_12 19 ydeAlellekalelaerllGpdhpltatalrnLgrlyl.algdyeeAlelleqalei 74 ++ A + l +a+e+ ++ +G+d+ + a++ + ++ y ++A ++le+++++ FUN_000204-T2 293 HERATQVLLQAHEISRARYGEDSIEFAESSFVVATSYInSFDGDAKAKNYLEDVVRL 349 78899999**************************99976889999999999998775 PP == domain 5 score: 8.0 bits; conditional E-value: 0.0027 TPR_12 20 deAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqa 71 ++A +le +++l + +Gp+h t+ a+ L+rl+ + g +eeA++l + + FUN_000204-T2 337 AKAKNYLEDVVRLNMQHRGPYHSSTIKAQDELSRLLVRGGFLEEAVSLQKSV 388 68999999******9999***************************9998865 PP == domain 6 score: 26.9 bits; conditional E-value: 3.4e-09 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +l +l r g ++eA +l++ + ++ l+G+ + + a +++ Lg + l++g++++Al++l + ++++ FUN_000204-T2 367 ELSRLLVRGGFLEEAVSLQKSVADAKVVLYGDPSQEAADCYQMLGSIRLKQGRLQQALKWLTKGYNML 434 6777888999*****************************************************99986 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.1 0.19 3.3e+02 1 15 [. 130 144 .. 130 144 .. 0.94 2 ? 4.8 0.1 0.031 53 4 28 .. 188 212 .. 186 217 .. 0.86 3 ! 14.4 0.1 2.6e-05 0.044 6 30 .. 237 261 .. 233 264 .. 0.92 4 ? -0.1 0.0 1.2 2e+03 18 33 .. 337 352 .. 336 353 .. 0.87 5 ! 12.3 0.1 0.00012 0.21 1 26 [. 404 429 .. 404 433 .. 0.92 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.19 TPR_2 1 aealynlGlayyklg 15 a+a+ l++ay+++g FUN_000204-T2 130 AKAHSKLSQAYLEQG 144 799**********98 PP == domain 2 score: 4.8 bits; conditional E-value: 0.031 TPR_2 4 lynlGlayyklgdyeeAleayekAl 28 + +G+a ++l++ +A++ ++kA FUN_000204-T2 188 YLVMGKAQLALKNTHKAEQNLKKAE 212 66789*****************995 PP == domain 3 score: 14.4 bits; conditional E-value: 2.6e-05 TPR_2 6 nlGlayyklgdyeeAleayekAlel 30 lG+a++++++ Alea+ekAl++ FUN_000204-T2 237 SLGRACLRANKSGHALEAFEKALQI 261 59*********************98 PP == domain 4 score: -0.1 bits; conditional E-value: 1.2 TPR_2 18 eeAleayekAleldPn 33 ++A++++e +++l+ + FUN_000204-T2 337 AKAKNYLEDVVRLNMQ 352 69**********9976 PP == domain 5 score: 12.3 bits; conditional E-value: 0.00012 TPR_2 1 aealynlGlayyklgdyeeAleayek 26 a+++ +lG + +k+g++++Al+++ k FUN_000204-T2 404 ADCYQMLGSIRLKQGRLQQALKWLTK 429 68999******************988 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.6 0.0 0.0033 5.6 19 40 .. 105 126 .. 104 128 .. 0.94 2 ? -3.3 0.0 9.1 1.5e+04 7 16 .. 135 144 .. 134 148 .. 0.78 3 ! 6.9 0.1 0.0053 9 8 40 .. 238 270 .. 231 272 .. 0.81 4 ? 4.5 0.2 0.032 54 18 41 .. 293 316 .. 276 317 .. 0.81 5 ? -2.8 0.0 6.1 1e+04 21 31 .. 339 349 .. 337 350 .. 0.83 6 ? 4.5 0.0 0.032 55 1 37 [. 361 397 .. 361 402 .. 0.80 7 ! 8.0 0.0 0.0024 4.1 2 40 .. 404 442 .. 403 442 .. 0.91 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0033 TPR_10 19 eeAeelleealairervlGpdH 40 e+A+ ++ +++a+ + ++G++H FUN_000204-T2 105 ERAVSDCVRCVALSRILHGDNH 126 689******************* PP == domain 2 score: -3.3 bits; conditional E-value: 9.1 TPR_10 7 nLanalraqg 16 L++a+ +qg FUN_000204-T2 135 KLSQAYLEQG 144 5999999999 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0053 TPR_10 8 LanalraqgryeeAeelleealairervlGpdH 40 L++a + ++ A+e +e+al+i+++ +G+d+ FUN_000204-T2 238 LGRACLRANKSGHALEAFEKALQITQAQYGDDS 270 5566666667778*************9999997 PP == domain 4 score: 4.5 bits; conditional E-value: 0.032 TPR_10 18 yeeAeelleealairervlGpdHP 41 +e+A + l +a +i ++ +G+d+ FUN_000204-T2 293 HERATQVLLQAHEISRARYGEDSI 316 689******************986 PP == domain 5 score: -2.8 bits; conditional E-value: 6.1 TPR_10 21 Aeelleealai 31 A ++le+++++ FUN_000204-T2 339 AKNYLEDVVRL 349 899****9985 PP == domain 6 score: 4.5 bits; conditional E-value: 0.032 TPR_10 1 tasslnnLanalraqgryeeAeelleealairervlG 37 t+ + + L+++l + g +eeA+ l++ + + ++G FUN_000204-T2 361 TIKAQDELSRLLVRGGFLEEAVSLQKSVADAKVVLYG 397 5667889*****************8887776666666 PP == domain 7 score: 8.0 bits; conditional E-value: 0.0024 TPR_10 2 asslnnLanalraqgryeeAeelleealairervlGpdH 40 a+++ L+ + +qgr++ A+++l + + +lG H FUN_000204-T2 404 ADCYQMLGSIRLKQGRLQQALKWLTKGYNMLTVTLGTSH 442 899*********************999888888888887 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.2 0.1 0.0084 14 4 27 .. 188 211 .. 186 215 .. 0.91 2 ! 11.6 0.0 0.00016 0.27 6 30 .. 237 261 .. 234 261 .. 0.93 3 ! 10.5 0.0 0.00036 0.62 1 26 [. 404 429 .. 404 430 .. 0.91 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0084 TPR_1 4 lynlGnayfklgkydeAleyyekA 27 + +G a ++l++ +A++ +kA FUN_000204-T2 188 YLVMGKAQLALKNTHKAEQNLKKA 211 67799*****************99 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00016 TPR_1 6 nlGnayfklgkydeAleyyekALel 30 lG a+++ +k Ale++ekAL++ FUN_000204-T2 237 SLGRACLRANKSGHALEAFEKALQI 261 5999*******************97 PP == domain 3 score: 10.5 bits; conditional E-value: 0.00036 TPR_1 1 akalynlGnayfklgkydeAleyyek 26 a+++ lG + +k+g++++Al+ k FUN_000204-T2 404 ADCYQMLGSIRLKQGRLQQALKWLTK 429 789999***************98876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.1 1.8 3.1e+03 1 15 [. 130 144 .. 130 150 .. 0.78 2 ! 7.6 0.3 0.0041 6.9 3 27 .. 187 211 .. 186 215 .. 0.95 3 ! 9.7 0.1 0.00089 1.5 5 32 .. 236 263 .. 232 265 .. 0.88 4 ? 1.4 0.0 0.38 6.6e+02 19 31 .. 338 350 .. 336 353 .. 0.89 5 ! 12.5 0.1 0.00011 0.18 1 27 [. 404 430 .. 404 433 .. 0.91 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.8 TPR_8 1 aeayynlGliylklg 15 a+a+ +l+++yl++g FUN_000204-T2 130 AKAHSKLSQAYLEQG 144 577788999998887 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0041 TPR_8 3 ayynlGliylklgdyeeAkeyyeka 27 +y+ +G++ l l++ ++A++ ++ka FUN_000204-T2 187 IYLVMGKAQLALKNTHKAEQNLKKA 211 6999********************8 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00089 TPR_8 5 ynlGliylklgdyeeAkeyyekaleldp 32 + lG+++l+ ++ A e++ekal++ + FUN_000204-T2 236 MSLGRACLRANKSGHALEAFEKALQITQ 263 689*********************9975 PP == domain 4 score: 1.4 bits; conditional E-value: 0.38 TPR_8 19 eAkeyyekaleld 31 +Ak+y+e +++l+ FUN_000204-T2 338 KAKNYLEDVVRLN 350 8*********997 PP == domain 5 score: 12.5 bits; conditional E-value: 0.00011 TPR_8 1 aeayynlGliylklgdyeeAkeyyeka 27 a+ y++lG+i lk+g++++A +++ k FUN_000204-T2 404 ADCYQMLGSIRLKQGRLQQALKWLTKG 430 689********************9985 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.1 0.11 1.8e+02 54 83 .. 189 218 .. 187 230 .. 0.88 2 ! 13.0 0.2 5.7e-05 0.097 54 105 .. 236 291 .. 234 310 .. 0.66 3 ? 2.0 0.0 0.14 2.4e+02 53 79 .. 407 433 .. 395 437 .. 0.81 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.11 TPR_CcmH_CycH 54 llLGriglslndaetAiqAfekAlklapnn 83 l++G+ +l+l+++++A q ++kA l++++ FUN_000204-T2 189 LVMGKAQLALKNTHKAEQNLKKAEILSQER 218 6799*******************9888876 PP == domain 2 score: 13.0 bits; conditional E-value: 5.7e-05 TPR_CcmH_CycH 54 llLGriglslndaetAiqAfekAlklap....nnteiklsYaqaLmlsgdeedlkk 105 + LGr l n+ A++AfekAl++++ ++++ + q L ++ + ++ FUN_000204-T2 236 MSLGRACLRANKSGHALEAFEKALQITQaqygDDSAELIPIYQCLAKAESSQGNAS 291 67************************972222233444445555555544444444 PP == domain 3 score: 2.0 bits; conditional E-value: 0.14 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlkl 79 +LG i l+++++++A++ + k +++ FUN_000204-T2 407 YQMLGSIRLKQGRLQQALKWLTKGYNM 433 569999999999999999988888875 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.3 0.1 0.0098 17 4 30 .. 237 263 .. 236 265 .. 0.92 2 ! 7.7 0.0 0.0037 6.3 4 24 .. 409 429 .. 406 430 .. 0.91 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0098 TPR_7 4 aLariyrklGdydeAirlyerlLalak 30 +L+r++ + ++ A++ +e++L++++ FUN_000204-T2 237 SLGRACLRANKSGHALEAFEKALQITQ 263 69********************99875 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0037 TPR_7 4 aLariyrklGdydeAirlyer 24 L++i k+G+ ++A++++++ FUN_000204-T2 409 MLGSIRLKQGRLQQALKWLTK 429 79***************9986 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.055 94 28 42 .] 130 144 .. 128 144 .. 0.92 2 ? 4.0 0.1 0.033 56 1 25 [. 239 263 .. 239 265 .. 0.78 3 ? 3.7 0.0 0.041 70 1 17 [. 411 427 .. 411 430 .. 0.88 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.055 TPR_11 28 aeayynLGlayykqG 42 a a+++L +ay++qG FUN_000204-T2 130 AKAHSKLSQAYLEQG 144 89************9 PP == domain 2 score: 4.0 bits; conditional E-value: 0.033 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldP 25 G+a+ +k A+ea++kAl++++ FUN_000204-T2 239 GRACLRANKSGHALEAFEKALQITQ 263 566666677778***********87 PP == domain 3 score: 3.7 bits; conditional E-value: 0.041 TPR_11 1 GdayyeqGkyeeAieaY 17 G + +qG++ +A++++ FUN_000204-T2 411 GSIRLKQGRLQQALKWL 427 78899*********987 PP >> P1 Major inner capsid protein P1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 3.3e-05 0.057 171 244 .. 99 181 .. 81 196 .. 0.78 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.3e-05 P1 171 iatfpdyralvDavraseLrRvle.....eLedaDvklvkaqfkk....kaAlapaliarelaaaataAseraRGsydaiavv 244 + + d ra+ D+vr L R+l+ +L++a +kl +a +++ Al a ar++ aa++A+++ R yd +v FUN_000204-T2 99 FKSMGDERAVSDCVRCVALSRILHgdnhwKLAKAHSKLSQAYLEQggmaEQALLHAENARNVLLAADTAKQQGRQVYDRSDVL 181 45566779***************7555557***********9987211144666666799*******************9995 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.8 1 1.8e+03 33 51 .. 132 150 .. 128 171 .. 0.61 2 ? 9.3 0.2 0.0013 2.2 30 61 .. 231 262 .. 189 267 .. 0.81 3 ? 6.9 0.0 0.0073 12 5 55 .. 370 428 .. 367 431 .. 0.73 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 1 TPR_16 33 AllglGlallrqgrlaeAa 51 A+ l +a+l+qg +ae a FUN_000204-T2 132 AHSKLSQAYLEQGGMAEQA 150 5555666666666555554 PP == domain 2 score: 9.3 bits; conditional E-value: 0.0013 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraalraa 61 ++++ lG+a+lr+++ A++a+++al++ FUN_000204-T2 231 RLEISMSLGRACLRANKSGHALEAFEKALQIT 262 557899**********************9765 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0073 TPR_16 5 raalaagdyddAaaaleaalrrn........PeaaaAllglGlallrqgrlaeAaaayr 55 r++++ g ++A+ + + ++++ eaa+ + lG + l+qgrl+ A++++ FUN_000204-T2 370 RLLVRGGFLEEAVSLQKSVADAKvvlygdpsQEAADCYQMLGSIRLKQGRLQQALKWLT 428 6666677777777555555555577777777778888889***************9985 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.2 5.8 9.9e+03 11 27 .. 141 157 .. 131 168 .. 0.63 2 ? 2.6 0.1 0.27 4.5e+02 4 27 .. 188 211 .. 186 221 .. 0.86 3 ? 8.1 0.1 0.0043 7.4 3 30 .. 234 261 .. 232 271 .. 0.87 4 ? -0.8 0.0 3.4 5.8e+03 4 27 .. 277 303 .. 275 310 .. 0.61 5 ? -1.0 0.0 3.7 6.4e+03 3 22 .. 364 383 .. 362 384 .. 0.83 6 ? 5.4 0.0 0.033 57 2 26 .. 405 429 .. 404 433 .. 0.89 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 5.8 TPR_14 11 llalGdpdeAlellera 27 l++ G ++Al ++e a FUN_000204-T2 141 LEQGGMAEQALLHAENA 157 34444666666655555 PP == domain 2 score: 2.6 bits; conditional E-value: 0.27 TPR_14 4 wlalarallalGdpdeAlellera 27 +l +++a lal+++++A++ l++a FUN_000204-T2 188 YLVMGKAQLALKNTHKAEQNLKKA 211 7889999999*******9999988 PP == domain 3 score: 8.1 bits; conditional E-value: 0.0043 TPR_14 3 awlalarallalGdpdeAlelleralal 30 + + l+ra+l++++ Ale++e+al+ FUN_000204-T2 234 ISMSLGRACLRANKSGHALEAFEKALQI 261 56789********************985 PP == domain 4 score: -0.8 bits; conditional E-value: 3.4 TPR_14 4 wlalarallalGd...pdeAlellera 27 ++ la+a+ +G+ +++A ++l +a FUN_000204-T2 277 YQCLAKAESSQGNassHERATQVLLQA 303 667888888888733344455554444 PP == domain 5 score: -1.0 bits; conditional E-value: 3.7 TPR_14 3 awlalarallalGdpdeAle 22 a+ l r+l++ G ++eA+ FUN_000204-T2 364 AQDELSRLLVRGGFLEEAVS 383 77889999999999999986 PP == domain 6 score: 5.4 bits; conditional E-value: 0.033 TPR_14 2 eawlalarallalGdpdeAleller 26 +++++l+ + l++G++++Al+ l + FUN_000204-T2 405 DCYQMLGSIRLKQGRLQQALKWLTK 429 67999****************9976 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.8 0.046 79 18 84 .. 142 212 .. 132 221 .. 0.65 2 ? 8.5 1.9 0.0015 2.6 10 86 .. 188 261 .. 183 285 .. 0.85 3 ? 3.6 0.2 0.049 84 17 106 .. 242 326 .. 238 333 .. 0.66 4 ? 4.9 0.0 0.02 34 14 51 .. 411 448 .. 403 459 .. 0.77 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.046 ARM_TT21 18 kkegkleeAlktLktAlklpgkkkskekkkekessesdkvs.....vylelidvlsklkkveeAkkllqeai 84 ++ g e+Al + ++A ++ ++ + ++ +++ ++ v +yl + ++ lk++++A++ l++a FUN_000204-T2 142 EQGGMAEQALLHAENARNVLLAADTAK-QQGRQVYDRSDVLpimelIYLVMGKAQLALKNTHKAEQNLKKAE 212 556677788888888888754332222.22333333333322334489999999999999999999988874 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0015 ARM_TT21 10 hlikakvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaiee 86 +l+ +k++ + +++++A + Lk+A l+++++ + + + + + ++++ ++l +++ +++k+ A +++++a++ FUN_000204-T2 188 YLVMGKAQLALKNTHKAEQNLKKAEILSQEREGRGYS---HQAMQRRLEISMSLGRACLRANKSGHALEAFEKALQI 261 68999999*****************998876665544...445678999***********************99976 PP == domain 3 score: 3.6 bits; conditional E-value: 0.049 ARM_TT21 17 lkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkve...eAkkllqeaieefkgtpeevrillanaelala 106 + +++k +Al+++++Al++++ + + + + + +y l+++ s++++++ A+++l +a e + e+ i +a++++ +a FUN_000204-T2 242 CLRANKSGHALEAFEKALQITQAQYGDD--------SAELIPIYQCLAKAESSQGNASsheRATQVLLQAHEISRARYGEDSIEFAESSFVVA 326 5567778889999999999976543332........235667777777776655444322268888888888888888888888887777766 PP == domain 4 score: 4.9 bits; conditional E-value: 0.02 ARM_TT21 14 akvlkkegkleeAlktLktAlklpgkkkskekkkekes 51 +++ k+g+l++Alk L++ +++ + + +++k++k++ FUN_000204-T2 411 GSIRLKQGRLQQALKWLTKGYNMLTVTLGTSHKRTKQM 448 677889****************9987777666666554 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 0.39 6.6e+02 9 27 .. 126 144 .. 124 151 .. 0.76 2 ? -0.6 0.1 1.9 3.2e+03 15 34 .] 187 206 .. 186 206 .. 0.84 3 ? -1.9 0.0 4.9 8.4e+03 15 28 .. 276 289 .. 274 293 .. 0.84 4 ? 9.0 0.0 0.0016 2.7 13 33 .. 404 424 .. 398 425 .. 0.92 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.39 TPR_17 9 dPnnadayynLArlllnnG 27 +++ a+a+ L +++l++G FUN_000204-T2 126 HWKLAKAHSKLSQAYLEQG 144 567789999*******997 PP == domain 2 score: -0.6 bits; conditional E-value: 1.9 TPR_17 15 ayynLArlllnnGqleeAlq 34 +y ++ ++l ++++ +A+q FUN_000204-T2 187 IYLVMGKAQLALKNTHKAEQ 206 57778999999999999987 PP == domain 3 score: -1.9 bits; conditional E-value: 4.9 TPR_17 15 ayynLArlllnnGq 28 +y++LA + + +G+ FUN_000204-T2 276 IYQCLAKAESSQGN 289 7999*999998887 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0016 TPR_17 13 adayynLArlllnnGqleeAl 33 ad+y++L+ + l++G+l++Al FUN_000204-T2 404 ADCYQMLGSIRLKQGRLQQAL 424 799*****************8 PP >> HTHP Hexameric tyrosine-coordinated heme protein (HTHP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.21 3.5e+02 36 58 .. 259 281 .. 232 286 .. 0.83 2 ? 7.7 0.1 0.0037 6.2 29 61 .. 297 329 .. 290 344 .. 0.76 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.21 HTHP 36 rkklReeYaeDaasLiavsqvvA 58 ++ ++Y +D+a+Li + q +A FUN_000204-T2 259 LQITQAQYGDDSAELIPIYQCLA 281 5556789*********9998877 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0037 HTHP 29 tqpdaevrkklReeYaeDaasLiavsqvvAveF 61 tq + + R++Y eD+ + ++s vvA+++ FUN_000204-T2 297 TQVLLQAHEISRARYGEDSIEFAESSFVVATSY 329 66666777788*******************974 PP >> MAS20 MAS20 protein import receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 2.9 4.9e+03 55 91 .. 117 153 .. 89 165 .. 0.60 2 ? 10.6 0.6 0.00037 0.62 42 119 .. 200 278 .. 191 288 .. 0.69 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 2.9 MAS20 55 ikealeeakeeplptdaeekeayFleevqlGEellaq 91 ++++l+ +++ +l + ++++ + +le+ + E+ l + FUN_000204-T2 117 LSRILHGDNHWKLAKAHSKLSQAYLEQGGMAEQALLH 153 4455555555566677777777777777777776655 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00037 MAS20 42 eeaeaekkkkkeaikealeeakeeplptdaeekeayFleevqlGEellaqgdeeeaalhlykAlkvypq.....PkeLlqilq 119 + ++k++++ + e+l+ +++e+ +++++++ +++lG ++l +++ +a++++ kAl++ + +eL+ i+q FUN_000204-T2 200 N---THKAEQNLKKAEILS-QEREGRGYSHQAMQRRLEISMSLGRACLRANKSGHALEAFEKALQITQAqygddSAELIPIYQ 278 2...222233332323333.34456668999**********************************976411112467777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (463 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 798 (0.031239); expected 510.9 (0.02) Passed bias filter: 527 (0.0206303); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4443.25 // Query: FUN_000205-T1 [L=433] Description: FUN_000205 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.15 12.7 0.4 0.15 12.7 0.4 2.5 3 Cnn_1N Centrosomin N-terminal motif 1 0.38 11.5 6.1 3.7 8.3 6.1 2.4 1 DUF7491 Coiled-coil region of unknown function (DUF7491) 4.6 8.4 9.0 1 10.5 4.4 2.2 3 YabA Initiation control protein YabA Domain annotation for each model (and alignments): >> Cnn_1N Centrosomin N-terminal motif 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.7 6e+03 38 69 .. 24 55 .. 18 63 .. 0.80 2 ? -1.4 0.3 0.45 3.8e+03 47 61 .. 65 78 .. 40 87 .. 0.55 3 ? 12.7 0.4 1.8e-05 0.15 11 35 .. 96 120 .. 93 145 .. 0.91 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.7 Cnn_1N 38 ieellkenvelkveleslqkelkklkkllkea 69 i+++ ++ l+++++ + +++k+k + ++ FUN_000205-T1 24 IQSMANQRHWLQDDNHIHRGDIDKCKGMAAQW 55 57777888889999999999999999877665 PP == domain 2 score: -1.4 bits; conditional E-value: 0.45 Cnn_1N 47 elkveleslqkelkk 61 +l+v e+l++ k+ FUN_000205-T1 65 QLQVITEELRQA-KQ 78 333333333332.33 PP == domain 3 score: 12.7 bits; conditional E-value: 1.8e-05 Cnn_1N 11 kLkkENFnLKLkihfleerleklap 35 +L+ EN nLKL+ + lee+ + +++ FUN_000205-T1 96 NLREENNNLKLRYFQLEEKYKATKQ 120 89*****************998877 PP >> DUF7491 Coiled-coil region of unknown function (DUF7491) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 6.1 0.00043 3.7 5 75 .. 34 104 .. 30 124 .. 0.87 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00043 DUF7491 5 lqgeNrelrqqisdlsststkyeellrrkeselaiLradvkrheeekksLekekeslssrhdemqarlrel 75 lq++N+ r +i++ +++ ++ + k+++l+++++++++ ++ +++L++ +++ h ++ ++ +l FUN_000205-T1 34 LQDDNHIHRGDIDKCKGMAAQWQQYTQEKDNQLQVITEELRQAKQLEQRLNSGMAKVVVDHANLREENNNL 104 8999***********************************************99999998888887766555 PP >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.3 0.15 1.3e+03 20 74 .. 13 67 .. 3 74 .. 0.60 2 ? 10.5 4.4 0.00012 1 8 74 .. 64 130 .. 59 138 .. 0.85 3 ? -3.9 0.0 3 2.6e+04 35 51 .. 400 416 .. 394 426 .. 0.53 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.15 YabA 20 llkeleelkeelaelleenaeLeiEnekLrerlkkeeekekekkkelsegkenLa 74 l++ +++ + +++++ ++ + L+ +n+ r ++k + ++ ++ ++e ++L+ FUN_000205-T1 13 LIQIINQQRIAIQSMANQRHWLQDDNHIHRGDIDKCKGMAAQWQQYTQEKDNQLQ 67 3444566667788888888888888888888885555555555554555444454 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00012 YabA 8 dqleeleeqleellkeleelkeelaelleenaeLeiEnekLrerlkkeeekekekkkelsegkenLa 74 +ql+ ++e+l++ + ++l + +a+++ ++a+L+ En++L+ r+ + eek k++k++l+ g + + FUN_000205-T1 64 NQLQVITEELRQAKQLEQRLNSGMAKVVVDHANLREENNNLKLRYFQLEEKYKATKQDLQYGLDLGR 130 5788899999999999999**************************8888888999988887776555 PP == domain 3 score: -3.9 bits; conditional E-value: 3 YabA 35 leenaeLeiEnekLrer 51 + + ++++ ++++r+ FUN_000205-T1 400 VSNSKTVTKKKSHIRRI 416 33444444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (433 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1551 (0.0607164); expected 510.9 (0.02) Passed bias filter: 537 (0.0210217); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4234.67 // Query: FUN_000206-T1 [L=154] Description: FUN_000206 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-05 25.9 0.0 2.7e-05 25.1 0.0 1.5 1 QIL1 MICOS complex subunit MIC13, QIL1 Domain annotation for each model (and alignments): >> QIL1 MICOS complex subunit MIC13, QIL1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.0 1.1e-09 2.7e-05 39 76 .. 50 86 .. 24 87 .. 0.70 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.1e-09 QIL1 39 lpklpsveeikfsaveyWNkgVkkvfsflselPtyake 76 + lp ++ + +++++WN+gV++ f++l+++P++a e FUN_000206-T1 50 IVSLPEMP-TQTKIKQSWNSGVQRAFNGLEQAPQTAWE 86 33344443.3347999*****************99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (154 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 713 (0.0279115); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1537.55 // Query: FUN_000207-T1 [L=169] Description: FUN_000207 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.034 15.0 0.0 0.42 11.4 0.0 2.3 2 DUF3848 Protein of unknown function (DUF3848) Domain annotation for each model (and alignments): >> DUF3848 Protein of unknown function (DUF3848) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 1.7e-05 0.42 9 34 .. 36 69 .. 26 84 .. 0.68 2 ? 1.0 0.0 0.029 7.4e+02 53 78 .. 102 127 .. 91 139 .. 0.72 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 1.7e-05 DUF3848 9 maaeqekyrdwlksqpp........eeilkhtye 34 +a eky dwlksq +eil+h e FUN_000207-T1 36 LALVGEKYSDWLKSQDSivqsfengQEILHHKEE 69 677889********96422222222678888755 PP == domain 2 score: 1.0 bits; conditional E-value: 0.029 DUF3848 53 araaallessspladvykefedlets 78 + al + l+ +yk ++++t+ FUN_000207-T1 102 QVSVALTACKYLLSSLYKRVQERDTA 127 34557777777788888888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (169 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 814 (0.0318653); expected 510.9 (0.02) Passed bias filter: 565 (0.0221178); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1664.89 // Query: FUN_000208-T1 [L=184] Description: FUN_000208 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 Tti2 Tti2 family ------ inclusion threshold ------ 0.071 13.6 1.3 29 5.3 0.2 3.6 4 F-box F-box domain Domain annotation for each model (and alignments): >> Tti2 Tti2 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 0.0 8.3e-11 1.1e-06 142 274 .. 2 127 .. 1 132 [. 0.85 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 8.3e-11 Tti2 142 GcelLqtllekleekkllrrtGLdsvfedallpcllyLPpltpeeeSlkllraaYpallsLykt.efaekkee...rnklldkilregilsgisha 233 G++++++++e ++++ l G ++vf +a++ +l+ e ++ a Yp+l+s++k+ ef+++k + ++++ d+i+ + +l+++ + FUN_000208-T1 2 GLRCVRHIVENMNSA-ELGWFGRADVFYEAIQRHLYTS------E--PSVVTALYPCLISILKVvEFSPTKPKfgrKTNKCDSIF-QTVLTSMEF- 86 899999999999999.999999999******9999865......2..2477899******9996377777777996777777777.669******. PP Tti2 234 sesprlvellleqlselvkelgisavkhLkrlipllgeils 274 ++++ + + ++l+ ++++gi++++h krl+ ++ ++l+ FUN_000208-T1 87 ESKIAMRRVCSSHLKHFIQHMGITTLRHFKRLLRVIFSYLE 127 4559********************************99887 PP >> F-box F-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.085 1.1e+03 8 22 .. 5 19 .. 3 23 .. 0.82 2 ? 5.3 0.2 0.0023 29 8 29 .. 76 97 .. 73 98 .. 0.87 3 ? 4.0 0.0 0.0058 74 8 23 .. 118 133 .. 116 133 .. 0.89 4 ? -3.2 0.0 1.1 1.4e+04 7 16 .. 135 144 .. 134 146 .. 0.72 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.085 F-box 8 llleIlsrLdpkdll 22 ++++I+++++ +l FUN_000208-T1 5 CVRHIVENMNSAELG 19 789******988875 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0023 F-box 8 llleIlsrLdpkdllrlslVSk 29 + + +l +++ + +++++V+ FUN_000208-T1 76 IFQTVLTSMEFESKIAMRRVCS 97 67889****************7 PP == domain 3 score: 4.0 bits; conditional E-value: 0.0058 F-box 8 llleIlsrLdpkdllr 23 ll+ I+s+L++ d+++ FUN_000208-T1 118 LLRVIFSYLEVSDYPN 133 7999*******99875 PP == domain 4 score: -3.2 bits; conditional E-value: 1.1 F-box 7 ellleIlsrL 16 e+ leIl+ L FUN_000208-T1 135 EARLEILDTL 144 6778899877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 635 (0.0248581); expected 510.9 (0.02) Passed bias filter: 532 (0.020826); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1850.00 // Query: FUN_000209-T1 [L=336] Description: FUN_000209 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-69 232.5 0.1 8.3e-69 232.2 0.1 1.1 1 Trypsin Trypsin 2.4e-05 25.3 11.0 3e-05 25.0 9.4 2.1 2 ShK ShK domain-like 0.00037 21.7 0.0 0.0014 19.9 0.0 1.8 1 Trypsin_2 Trypsin-like peptidase domain 0.00095 20.0 0.0 0.0016 19.3 0.0 1.4 1 DUF1986 Domain of unknown function (DUF1986) 0.0023 18.0 0.0 0.36 10.8 0.0 2.8 2 DUF316 Nematode trypsin-6-like family Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 232.2 0.1 1.6e-72 8.3e-69 1 220 [] 98 329 .. 98 329 .. 0.93 Alignments for each domain: == domain 1 score: 232.2 bits; conditional E-value: 1.6e-72 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegs.eqklkvekvivhpnynsdtl..dnDial 91 ivgg+ aq+g++pwq++l+ +g+ fCGG+li ++wvlTAaHCv+ +s+++v++g+h + ++++ eq +++e++i h+ yn++ + +Dial FUN_000209-T1 98 IVGGTAAQPGDWPWQAMLKSPRGSSFCGGTLIAPQWVLTAAHCVTRkwPSDFRVRMGAHMKNGNDPEgEQDFEIERIIKHESYNKKPYrnSYDIAL 193 89*********************99*********************************66665555459****************998889***** PP Trypsin 92 lklkspvtlgdavrpiclpaasssl...avgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsayggkvtdnmicagak.ggkdacqGDSGG 182 lkl++p++l+++v+ +clp++s +l ++c+++GwG+ +++g ++++l +++vp+vs+++c ++y +k+ d+m+cag++ gg+d+cqGDSGG FUN_000209-T1 194 LKLSTPAQLNKRVALACLPDTSVELpidDLSKKCWITGWGTLQSGGtSPKVLMQAQVPLVSKDRCLKSY-HKLHDSMLCAGYDeGGADTCQGDSGG 288 ********************7666611345679*********9************************75.669**********999********** PP Trypsin 183 Plvcsdg...eliGivswgkgcasgnkpgvytrvssyadwi 220 Plvc+ + + G +swg++cas+++ gvy++v ++++wi FUN_000209-T1 289 PLVCKYNgkwHVEGATSWGYKCASKGYFGVYAKVRYVLSWI 329 *****999********************************9 PP >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 9.4 5.9e-09 3e-05 2 37 .] 23 56 .. 22 56 .. 0.97 2 ? -3.0 0.0 3.1 1.6e+04 12 25 .. 306 318 .. 305 321 .. 0.69 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 5.9e-09 ShK 2 CvDpssdCaswaang.CnspayqdfmkenCpktCgfC 37 C D+++dC ++a+ + C+++ f+k C+k+Cg+C FUN_000209-T1 23 CYDKWPDCKNFADEDnCKNNL---FVKYRCQKSCGLC 56 *****************9996...************* PP == domain 2 score: -3.0 bits; conditional E-value: 3.1 ShK 12 waangCnspayqdf 25 w + C s+ y + FUN_000209-T1 306 WGYK-CASKGYFGV 318 7777.988887655 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 2.7e-07 0.0014 3 137 .. 126 292 .. 124 298 .. 0.61 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 2.7e-07 Trypsin_2 3 GfvvssdglvlTnaHvv...................adaeeaav...vaekvsvaladgreyaatvvaadpelDlallkv.....sedgaglpplp 71 G +++++ vlT+aH+v + + + ++ ++ + y + ++++ +D+allk+ + + +l++lp FUN_000209-T1 126 GTLIAPQW-VLTAAHCVtrkwpsdfrvrmgahmkngN------DpegEQDFEIERIIKHESYNKKPYRNS--YDIALLKLstpaqLNKRVALACLP 212 89999998.********99888888888886664321......222233455556666666666655555..8*******9876644444444444 PP Trypsin_2 72 lgdsa.....plvggervyavGy.plggekleslseGtvsavse.....srderddeell.....qtdaslspGsSGgPlfd 137 + + + +++ +G ++gg+++ +l +++v vs+ s ++ ++++l + a++ G SGgPl+ FUN_000209-T1 213 DTSVElpiddLSKKC-WITGWGTlQSGGTSPKVLMQAQVPLVSKdrclkS-YHKLHDSMLcagydEGGADTCQGDSGGPLVC 292 222112322033333.6666666656666666777777777777778743.33344444458888777777779*****997 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 3.2e-07 0.0016 1 103 [. 109 218 .. 109 231 .. 0.79 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 3.2e-07 DUF1986 1 wPwladvyl.eGdlicsGvlidkswvlvsescl...sdvdlehsyvsvvlGgaktkksvkgpyeqivrvdafkdvpks...evvllhlkskvsfsr 89 wPw a + G+ +c G li +wvl c+ + d++ + + + g+ + + e+i + +++++ p ++ ll l ++++ + FUN_000209-T1 109 WPWQAMLKSpRGSSFCGGTLIAPQWVLTAAHCVtrkWPSDFRVRMGAHMKNGNDPEGEQDFEIERIIKHESYNKKPYRnsyDIALLKLSTPAQLNK 204 99*99997537*********************822234566666666666666667777778899******987664312379************* PP DUF1986 90 hvlPtfvpesrnen 103 v +p+++ e+ FUN_000209-T1 205 RVALACLPDTSVEL 218 *********99876 PP >> DUF316 Nematode trypsin-6-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.012 59 29 95 .. 88 145 .. 86 171 .. 0.80 2 ! 10.8 0.0 7e-05 0.36 154 252 .. 182 305 .. 167 324 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.012 DUF316 29 esCGnktlpkkskknngiyaeksekeWlvlvafkngnekkylapatlISsrHiltssrviltskskW 95 +CG l ++s+ g+ a+ +W +++ g+ + +tlI + +lt ++ + +kW FUN_000209-T1 88 GTCG---LRPESRIVGGTAAQPGDWPWQAMLKSPRGSS---FCGGTLIAPQWVLTAAHCVT---RKW 145 5899...7777778788888888888888888888877...55***************998...667 PP == domain 2 score: 10.8 bits; conditional E-value: 7e-05 DUF316 154 kskqklsaapmlvelekp..leinssvvCladestsleksdavdvyglkssselkhrklkieavss.......................aalsikt 224 k+++++s+ + l+ l +p l++ +Cl+d+s +l +d + + ++ + l+++ ++++ ++ +a + FUN_000209-T1 182 KKPYRNSYDIALLKLSTPaqLNKRVALACLPDTSVELPIDDLSKKCWITGWGTLQSGGTSPKVLMQaqvplvskdrclksyhklhdsmlCAGYDEG 277 5778899999999999996666777789********************999999999999999988889999999999999988776654444445 PP DUF316 225 sqylskkedggplikkvsgkltviGfga 252 ++++++ggpl+ k +gk+ v G + FUN_000209-T1 278 GADTCQGDSGGPLVCKYNGKWHVEGATS 305 5679999*************99987654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 730 (0.028577); expected 510.9 (0.02) Passed bias filter: 461 (0.0180466); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3289.85 // Query: FUN_000210-T1 [L=792] Description: FUN_000210 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-85 286.0 5.1 4e-85 285.3 5.1 1.3 1 Peptidase_M1 Peptidase family M1 domain 3.9e-41 141.7 0.0 8.1e-41 140.6 0.0 1.5 1 Peptidase_M1_N Peptidase M1 N-terminal domain 2e-32 113.4 1.3 5.9e-32 111.8 1.4 1.8 2 ERAP1_C ERAP1-like C-terminal domain Domain annotation for each model (and alignments): >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 285.3 5.1 4.7e-89 4e-85 1 218 [] 354 577 .. 354 577 .. 0.98 Alignments for each domain: == domain 1 score: 285.3 bits; conditional E-value: 4.7e-89 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 +al v++k+l+f+ee+f+v+Yplpk dl+a+pdf++gaMEnwglit+r +++l+d ++ss ++k+ va v+aHElaHqWfGnlVtmkwW+dlwLnE FUN_000210-T1 354 FALSVAVKVLQFYEEKFQVDYPLPKQDLIAIPDFPTGAMENWGLITFRLTSILFDVNKSSRRNKQWVAVVVAHELAHQWFGNLVTMKWWSDLWLNE 449 7899******************************************************************************************** PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfas++e ++++ ++pewk+++++ l++ +k +a D l++shpi ev+++++i+++Fd+isY+KGas++rmle++lg +vf kgl++Ylkk++++ FUN_000210-T1 450 GFASFVENVGVNFTNPEWKMMDQFYLDKFQKSMALDQLSNSHPIMAEVKDPAQINSLFDSISYDKGASIIRMLENVLGTDVFFKGLQKYLKKYSFS 545 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasg......kdvkslmdtw 218 na+t+dlwd l++a+ dvk++m tw FUN_000210-T1 546 NAETNDLWDCLTQAARdeqqkeIDVKQMMTTW 577 *************65556666689*******9 PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 140.6 0.0 9.6e-45 8.1e-41 2 186 .] 121 319 .. 120 319 .. 0.83 Alignments for each domain: == domain 1 score: 140.6 bits; conditional E-value: 9.6e-45 Peptidase_M1_N 2 pehYdldlkinlkektfkGsvtitlqlknatssivlna.kelei.....kkvslsaevasesvkv..dfkveqkdeekltiklpes..lqqtssv 86 p Y + l++nl+++tf+G+v + l ++ ++++i+l+ +l+i k +s+++ + e vk+ kv+ +e l+i+l ++ lq+ + + FUN_000210-T1 121 PIEYLVYLHPNLTTFTFSGKVDVLLYCSVSANNITLHVgDKLNIlessvKVASIQDPLGKETVKLldVAKVDRAPGEMLVITLHKNslLQSGGYY 215 889999*******************************6368999987665556666666666665222466777888888777543115559999 PP Peptidase_M1_N 87 tLeieysgel.ndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpviesekledgkk..itkFe 177 L ie+s el n+ l G+y stY + +g k+++a+T+fe+tdAR+afPcfDeP+ Ka+f+i i +k +val+Nmp ++++ +++ +++Fe FUN_000210-T1 216 FLAIEFSSELnNTRLSGFYLSTYYTlSGDKRYLATTHFEPTDARNAFPCFDEPDLKARFSIVIVREKRHVALANMPLNHTDGCDKEADlcTDHFE 310 **********77789****6666666**************************************************999887664444459**** PP Peptidase_M1_N 178 etpkmstYL 186 +++kmstYL FUN_000210-T1 311 KSVKMSTYL 319 ********9 PP >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 0.61 5.2e+03 191 221 .. 246 275 .. 245 315 .. 0.76 2 ! 111.8 1.4 7e-36 5.9e-32 1 126 [. 658 791 .. 658 792 .] 0.90 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 0.61 ERAP1_C 191 rykdttsasekeaalralaatpdpellerll 221 ry tt e + a +a ++ +p+l++r+ FUN_000210-T1 246 RYLATTH-FEPTDARNAFPCFDEPDLKARFS 275 6777776.8889999999********99964 PP == domain 2 score: 111.8 bits; conditional E-value: 7e-36 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalarag.elstsdaldlvkaylknEteyvvwsaalsqlstlkslls.. 91 w+k N+++tGyyr+nYd+ ++ kl++ql+ ++vls++dRaglidda +lara ls ++a+dl++ ylknE+ey++w +al++++++++ +s FUN_000210-T1 658 WIKMNSGQTGYYRINYDAVNWCKLGHQLAtdHTVLSAADRAGLIDDALNLARADaGLSDDQAMDLTL-YLKNEKEYIPWMSALNNFAYFATQFStl 752 9*************************9999**********************872566677*****9.999******************9999776 PP ERAP1_C 92 ....edpvyealkaflrkllsplleklgweekpgeshld 126 ++++y+++k+++ l+++l+++lgwee p++ hl+ FUN_000210-T1 753 dsegKTEYYASYKKYIYYLIKELAHELGWEEMPDDGHLK 791 3433345899*******************8888988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (792 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1100 (0.0430613); expected 510.9 (0.02) Passed bias filter: 846 (0.033118); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.38s 00:00:00.79 Elapsed: 00:00:00.41 # Mc/sec: 7736.33 // Query: FUN_000210-T2 [L=663] Description: FUN_000210 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-85 285.5 6.8 5.2e-85 285.0 6.8 1.3 1 Peptidase_M1 Peptidase family M1 domain 3.4e-41 141.9 0.0 5.8e-41 141.1 0.0 1.4 1 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 Aminopep Putative aminopeptidase Domain annotation for each model (and alignments): >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 285.0 6.8 6.1e-89 5.2e-85 1 218 [] 354 577 .. 354 577 .. 0.98 Alignments for each domain: == domain 1 score: 285.0 bits; conditional E-value: 6.1e-89 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 +al v++k+l+f+ee+f+v+Yplpk dl+a+pdf agaMEnwglityr ++ll+d ++ss+++k+ va v+aHElaHqWfGnlVtmkwW+dlwLnE FUN_000210-T2 354 FALSVAVKVLQFYEEKFQVDYPLPKQDLIAIPDFAAGAMENWGLITYRLTSLLYDEHKSSIANKEWVAVVVAHELAHQWFGNLVTMKWWSDLWLNE 449 7899******************************************************************************************** PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfas++e ++++ ++pewk+++++ l++ +k +a D l++shpi ev+++++i+++Fd+isY+KGas++rmle++lg +vf kgl++Ylkk++++ FUN_000210-T2 450 GFASFVENVGVNFTNPEWKMMDQFYLDKFQKSMALDQLSNSHPIMAEVKDPAQINSLFDSISYDKGASIIRMLENVLGTDVFFKGLQKYLKKYSFS 545 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasg......kdvkslmdtw 218 na+t+dlwd l++a+ dvk++m tw FUN_000210-T2 546 NAETNDLWDCLTQAARdeqqkeIDVKQMMTTW 577 *************65556666689*******9 PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 141.1 0.0 6.9e-45 5.8e-41 2 186 .] 121 319 .. 120 319 .. 0.83 Alignments for each domain: == domain 1 score: 141.1 bits; conditional E-value: 6.9e-45 Peptidase_M1_N 2 pehYdldlkinlkektfkGsvtitlqlknatssivlna.kelei.....kkvslsaevasesvkv..dfkveqkdeekltiklpes..lqqtssv 86 p Y + l++nl+++tf+G+v + l ++ ++++i+l+ +l+i k +s+++ + e vk+ kv+ +e l+i+l ++ lq+ + + FUN_000210-T2 121 PIEYLVYLHPNLTTFTFSGKVDVLLYCSVSANNITLHVgDKLNIlessvKVASIQDPLGKETVKLldVAKVDRAPGEMLVITLHKNslLQSGGYY 215 889999*******************************6368999987665556666666666665222466777888888777543115559999 PP Peptidase_M1_N 87 tLeieysgel.ndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpviesekledgkk..itkFe 177 L ie+s el n+ l G+y stY + +g k+++a+T+fe+tdAR+afPcfDeP+ Ka+f+i i +k +val+Nmp ++++ +++ +++Fe FUN_000210-T2 216 FLAIEFSSELnNTRLSGFYLSTYYTlSGDKRYLATTHFEPTDARNAFPCFDEPDLKARFSIVIVREKRHVALANMPLNHTDGCDKEADlcTDHFE 310 **********77789****6666666**************************************************999887664444459**** PP Peptidase_M1_N 178 etpkmstYL 186 +++kmstYL FUN_000210-T2 311 KSVKMSTYL 319 ********9 PP >> Aminopep Putative aminopeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 2.9e-05 0.24 148 185 .. 418 461 .. 411 487 .. 0.80 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 2.9e-05 Aminopep 148 eeLarlifHElaHq......tlYvkgdtafnEsfAtfveregae 185 e +a ++ HElaHq t+ +d +nE fA+fve+ g++ FUN_000210-T2 418 EWVAVVVAHELAHQwfgnlvTMKWWSDLWLNEGFASFVENVGVN 461 5578899******9444433344568999***********9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (663 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1177 (0.0460756); expected 510.9 (0.02) Passed bias filter: 910 (0.0356234); expected 510.9 (0.02) Passed Vit filter: 74 (0.00289685); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6348.79 // Query: FUN_000211-T1 [L=525] Description: FUN_000211 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (525 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 709 (0.0277549); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.42s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5069.97 // Query: FUN_000211-T2 [L=345] Description: FUN_000211 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (345 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 517 (0.0202388); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3429.12 // Query: FUN_000212-T1 [L=945] Description: FUN_000212 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-87 295.0 0.7 1.6e-87 294.4 0.7 1.3 1 ERAP1_C ERAP1-like C-terminal domain 1.7e-83 280.0 0.8 4.1e-83 278.8 0.8 1.7 1 Peptidase_M1 Peptidase family M1 domain 9.2e-48 163.3 4.1 1.8e-46 159.1 4.1 2.4 1 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.098 13.6 0.0 0.29 12.1 0.0 1.8 1 RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7 Domain annotation for each model (and alignments): >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 294.4 0.7 2.6e-91 1.6e-87 1 318 [] 599 916 .. 599 916 .. 0.96 Alignments for each domain: == domain 1 score: 294.4 bits; conditional E-value: 2.6e-91 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlksllsedp 94 w+k+N+d+ GyyrvnY+++++ +l+ ql +kvls++dR gliddaf lar+++l+ + al+l++ y k+Et+y ++++ +++++++ s l+ + FUN_000212-T1 599 WIKANVDQIGYYRVNYEKKNWINLGLQLYldHKVLSAADRSGLIDDAFHLARSNQLDQTIALSLTE-YIKHETDYSPLRTFITNMNYIGSQLAMRD 693 9***********************9987799**********************************9.768**********************8455 PP ERAP1_C 95 vyealkaflrkllsplleklgweekpgeshldqqlrslllsaacsagdeevvaeakklfeawlegddsaippdlrwavlcaavanggeaewdalle 190 +y+ +k +++++++p +++lgwe+ +g shld++lr +l++ac++g+ v+++ k+lf++ ++g + +ip++lr v++++v++gge ew++++ FUN_000212-T1 694 TYSIFKVYMLQQIQPQIQRLGWED-KG-SHLDKLLRPIILRTACECGETTVISKIKDLFHQAVTGHK-TIPSNLRALVYSIGVREGGEVEWNQVFC 786 8*********************66.45.9**********************************9964.8*************************** PP ERAP1_C 191 rykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlaglasnpagrelawdfvkenwdelekrlgggs.slgrlvkgltpsfs 285 +y +t+ ase++ +l al +t+dp l+++ l+++ld++++r+qd+ +v++++a p++ ++awdfv++nwd l+kr++ gs ++ l+++l+ + + FUN_000212-T1 787 KYSTTHIASERRILLDALTYTRDPYLVQKCLKYSLDKGKIRSQDTLSVISNVALDPQTWRMAWDFVRKNWDILYKRYSRGSdLWQWLISSLMMKCN 882 **99999*********************************************999**********************9877799************ PP ERAP1_C 286 teeeldeveaFfadkdtpglr.ralaqaletirr 318 t+ +l+e+ +Ff+d + ++ r ++ ++e++r+ FUN_000212-T1 883 TQVQLNEIMDFFKDYKATAAGyRQVQMGIERVRA 916 **************965555559********985 PP >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 278.8 0.8 6.4e-87 4.1e-83 1 218 [] 304 521 .. 304 521 .. 1.00 Alignments for each domain: == domain 1 score: 278.8 bits; conditional E-value: 6.4e-87 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 +al++++k+l+ +ee f++++plpk dlva+pdf +gaMEnwgli + ++l+dp+++s+s ++ v ++++HElaHqWfGnlVtmkwW+dlwLnE FUN_000212-T1 304 FALHIAAKTLSHYEEFFRIKFPLPKQDLVAIPDFGTGAMENWGLIGFSAAMVLFDPKKTSDSLQQVVCQTVTHELAHQWFGNLVTMKWWNDLWLNE 399 799********************************************************************************************* PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfa+y+e +++ +ep w+++++++++ +++a+aeD ++ shpisv ve++++id++Fd+isYeKGas++rml+++lg ++f +gl+ Ylkk++++ FUN_000212-T1 400 GFATYVENIGCSMVEPRWRMMDQFQVDVLQTAFAEDQSSYSHPISVDVEDPKDIDSIFDSISYEKGASIIRMLRNFLGSDEFTSGLQLYLKKYSFA 495 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasgkdvkslmdtw 218 na+t+dlw+ l+e+s +vk++mdtw FUN_000212-T1 496 NADTDDLWECLSEKSAINVKEIMDTW 521 ************************** PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.1 4.1 2.7e-50 1.8e-46 2 186 .] 56 269 .. 55 269 .. 0.93 Alignments for each domain: == domain 1 score: 159.1 bits; conditional E-value: 2.7e-50 Peptidase_M1_N 2 pehYdldlkinlkektfkGsvtitlqlknatssivlnakelei............................kkvslsaevasesvkvdfkveqkd 68 p +Y+++l+++l+ ++++Gsv+i++q+ +at++++l+ k++++ k ++ e++ e+ +v ++++ ++ FUN_000212-T1 56 PLNYKITLQTDLDAFHVRGSVKIRVQCLKATKNLILHLKDMNVinaavfkndkdqsvpekdiyddeelitkLKGKEEIEEEVEKLQVIKTMQSER 150 89*************************************************************99988854233333456667777778888888 PP Peptidase_M1_N 69 eekltiklpeslqqtssvtLeieysgelndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpvi 162 e + i+++e+l +++ + i ++ l+d l G+y+s+Yt +ge++++a+T fe+t+AR+afPcfDeP++Katft+si+ + +++alSNmp + FUN_000212-T1 151 IEMFLIEVSEQLTPRQHYDMYITFEYPLTDGLLGFYRSYYTAkDGERRYLAATLFEPTEARRAFPCFDEPAMKATFTVSIIRQGKYTALSNMPIE 245 888***************************************9999************************************************* PP Peptidase_M1_N 163 esekledgkkitkFeetpkmstYL 186 ++ k ++ +++F+e+ kms+YL FUN_000212-T1 246 KTVKISEDLFVDHFKESEKMSSYL 269 ******9999*************9 PP >> RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 4.6e-05 0.29 6 43 .. 340 376 .. 337 412 .. 0.88 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 4.6e-05 RNA_pol_Rpb2_7 6 GEMEvwaleayGaaklLkerltikSDavevdvcgrckl 43 G ME w l+++ aa++L + ++SD+++ vc+++ + FUN_000212-T1 340 GAMENWGLIGFSAAMVLFDP-KKTSDSLQQVVCQTVTH 376 89***************997.57899999999998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (945 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 958 (0.0375024); expected 510.9 (0.02) Passed bias filter: 567 (0.0221961); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.42u 0.37s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 9087.60 // Query: FUN_000213-T1 [L=1568] Description: FUN_000213 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-179 598.0 0.0 4.1e-179 597.5 0.0 1.2 1 RdRP RNA dependent RNA polymerase 1.5e-24 87.3 1.5 3.4e-24 86.2 1.5 1.6 1 RdRP_head RdRP, head domain 3.3e-07 30.5 3.9 3.3e-07 30.5 3.9 2.3 2 PH_met_RdRP Metazoan RdRP associated PH-like domain ------ inclusion threshold ------ 0.018 15.6 0.1 0.43 11.2 0.0 3.0 3 RdRP_helical RNA dependent RNA polymerase, helical domain 0.11 13.1 0.1 0.34 11.5 0.1 1.9 1 DUF7752 Domain of unknown function (DUF7752) Domain annotation for each model (and alignments): >> RdRP RNA dependent RNA polymerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 597.5 0.0 7.9e-183 4.1e-179 1 583 [. 412 985 .. 412 986 .. 0.90 Alignments for each domain: == domain 1 score: 597.5 bits; conditional E-value: 7.9e-183 RdRP 1 vtptrillegpeleksnrvlRrfkegsdrflrvqfpdedleq.rlnsevdseeevfervkkllkegikiagrkfeflafsnsqlrehsvwffapfe 95 +tpt+ +l +pel nrv+R + g+++ +r+ f+ded ++ + +++ +++++erv +ll++ i+i+grkfefla+snsqlr+h++w++a FUN_000213-T1 412 ITPTQRFLIPPELVAENRVIRDY--GHENAMRIAFRDEDFSKlSSTHREGLNDVLQERVMDLLSQHIEIGGRKFEFLACSNSQLRDHGAWLYAV-- 503 79*********************..**************996554455455*****************************************94.. PP RdRP 96 esgervtveeirkwlgdfsnieqsvaKyaaRlgqafSktratvvkveeee.i.veeipD..........evrngkkiyv..........ftDGvGk 169 +ge ++++ir++lg++++i ++va y++R+gq+fS+t+++ v+++ ee e+ipD + + f+DGvGk FUN_000213-T1 504 -EGE-HRAHDIRSSLGRLTEI-RCVATYVSRMGQCFSSTKEA-VTINIEEgFeNEQIPDvemefkdvffK--------CcqnwrsgtytFSDGVGK 587 .333.69**************.*******************5.4445555555899**975544444443........23555555555******* PP RdRP 170 iSrelarkiakelglkkeelPsafQiRlgGaKGvlavdkel...p.kdwielrpSmiKfeseeesrtLeivkaskkpkpayLnrqlIkiLedlgvp 261 iSr+lark+a++l+l +++Psa+QiR+gG+KG+la+d++l + ++ + r+Sm+Kf+s +r Lei+++sk++ +yLnrq I++L+ lgvp FUN_000213-T1 588 ISRALARKVADSLNL--DPIPSAYQIRFGGCKGMLAIDPSLphgNfREILLYRKSMRKFDST--HRVLEICETSKPN-LLYLNRQCIILLSGLGVP 678 ***************..69**********************765344468899******776..666********99.****************** PP RdRP 262 devflelleealeeleealkdaelaaelleksgdpaeleellaellkagfepkelkdpflrsllkllvkkklrelkekarIpvp..ksatllgvaD 355 d+vf+ l++e+l++l+++l +++a++ l++ p ++ ++l ++g++ + +pf+rsll +++k++l +l ++arI +p +++ l+gv+D FUN_000213-T1 679 DDVFIGLQDEMLRTLASILLFESVALDSLRRITIPGGMKF--TSLSRSGINVT--LEPFFRSLLLAVYKSRLGDLLRRARIAIPetHGRLLMGVMD 770 *****************************98877777765..57779999655..39***************************888********* PP RdRP 356 etgvLeegevfvqfssatve.eekektkllegkvlVaRnPalhpgDiqvvravdvpelrhlkdvvVFsqkGdrplpselsGGDlDGDlywviwdpe 450 etg L++g+vfv++s+ + + ++ + k+l+g+v++++nP+ hpgD++ ++avdv++l+hl+d++VF+ G+rp+p+e+sG+DlDGD+y+v+w + FUN_000213-T1 771 ETGSLQYGQVFVRYSKSVSQpGK--ELKTLDGRVVISKNPCFHPGDMRTFKAVDVEALHHLVDCIVFPAIGPRPHPNEMSGSDLDGDKYFVTWLDK 864 **************995444344..599999***************************************************************** PP RdRP 451 lefapakptneepadyeaakpkeldrevtvediadffveymksdvlGlianahlaiadqseegvkdekclkLaelhskaVDypKtGipvekkelpr 546 l p+ ++neep+d++a+++k+l+r+v+v+d+ +f+ +y+k+d+lG+ianahl++ad +++g+++++c++La++hs+aVD+pKtG+ + l++ FUN_000213-T1 865 LI--PT-RRNEEPMDFTAPEKKTLTRPVQVSDMIEFVSDYIKNDQLGIIANAHLVHADYNKDGIFSPECIQLAHMHSDAVDFPKTGKCPT---LSK 954 *5..55.68899******************************************************************************...999 PP RdRP 547 elkkpkekPdfkekekkekkkkkyyksekilGkLyre 583 el +p ++Pdf++k+ k+ yks++ilG+L+r+ FUN_000213-T1 955 EL-RPDQYPDFMMKTG-----KPQYKSNRILGRLFRK 985 99.7999*****6553.....367***********98 PP >> RdRP_head RdRP, head domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 86.2 1.5 6.7e-28 3.4e-24 3 136 .. 1008 1174 .. 1006 1186 .. 0.85 Alignments for each domain: == domain 1 score: 86.2 bits; conditional E-value: 6.7e-28 RdRP_head 3 dedlevpgfedfleeakawkenYdekLtqlmdyYrvkteeeiltGiillllkrdskkqg.....kdriklavneLrkea..............a 77 dedl+v g+e +le+a+a +++Y++kL lm++Y+ k+e e++tG++ ++ r s k + ++ i+++ Lr ++ + FUN_000213-T1 1008 DEDLKVRGYERYLEDAEAARKHYNAKLEGLMSLYGLKNEGEVITGCLFRVNTRLSAKTDekfevAQMIQASLATLRAKTredfyaefggeeavM 1101 89*********************************************55555544444444447999***********9999999999999999 PP RdRP_head 78 seFeeskedeenlekkAsAwYqvtYhpairekkl..............aflsFaWvagdvLlrikaesakrke 136 eFee ++ +++ +kAsAwY vtY++ + + +sF+Wv+ + L++ik ++ ++ FUN_000213-T1 1102 EEFEENESFGDEVMMKASAWYMVTYDQVDQTSGSsqrdyqtadarteiQLISFPWVVDRILAEIKDMKQEERQ 1174 999999999999**************866554445799***************************96553333 PP >> PH_met_RdRP Metazoan RdRP associated PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 3.9 6.4e-11 3.3e-07 8 204 .. 121 278 .. 116 291 .. 0.78 2 ? -3.2 0.1 1.3 6.7e+03 26 64 .. 1260 1299 .. 1250 1312 .. 0.69 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 6.4e-11 PH_met_RdRP 8 ipleaiafGNilnggtFlnhwevsfpeetnseklqellkvlrelrkadikspmladFeHDrriltvrFavreeykkreveesnekgleeavyqlkv 103 ++ +++ fG+++n+gt++ hw+ + ++ k ++ ++++FeHD ++l++ F r+ ++ + +++++ FUN_000213-T1 121 LRANSFGFGSFFNRGTYIEHWSSQD--DCLFIK----------------ENHIQIEFEHDAKQLVISFFERDDTQ------------VFKEVRIEM 186 67799*****************994..455443................578****************9998722............45679**** PP PH_met_RdRP 104 rynsIrr.iivdle..dekgedrvriyfqlnyPpeirrfrkkknkkgkkklesegkRvlswpegdrkedeesseeaiseSpvfclefkeed...sd 193 y + +++d++ + + ++++++y+ l++Pp++ + k + ++++kRv + + + +e++ ++v+cl+f+e+ ++ FUN_000213-T1 187 DYRHLETyVVIDNNsdQTSPQKTIKLYIPLQFPPKVFQEVKLGE-------YTNYKRVTHFLK--------CCREVLGSCSVLCLCFPENWqenKA 267 ******9667799976555778899**********988555554.......467888775555........5799999999999999987522234 PP PH_met_RdRP 194 eelydilsRLr 204 + +++RL FUN_000213-T1 268 DSPSALIARLS 278 45666777765 PP == domain 2 score: -3.2 bits; conditional E-value: 1.3 PH_met_RdRP 26 nhwevsfpeetnseklqellkvlrelrk.adikspmladF 64 h++ +++ +++ lq+l ++++++ + + +++p+ +F FUN_000213-T1 1260 AHFKWNASVPEQRQYLQHLQRSFKKFGDtNITRNPLILHF 1299 5655555555666666777777777776344466777666 PP >> RdRP_helical RNA dependent RNA polymerase, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.21 1.1e+03 28 78 .. 35 87 .. 31 90 .. 0.74 2 ? 11.2 0.0 8.5e-05 0.43 12 46 .. 308 342 .. 305 347 .. 0.93 3 ? -3.6 0.0 3.3 1.7e+04 16 31 .. 1054 1069 .. 1053 1088 .. 0.59 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.21 RdRP_helical 28 ivqkaldaelfklLeevpeevsvdilrklkk.lsm.vcyeaavwlkleqksia 78 +k+l + f+ Lee ++ ++ +r+ k l+ +++a+++ + +k + FUN_000213-T1 35 GDFKHLLRRYFQVLEEPSKPTNTGNIRNIKFtLKDaKMFGKAQFFEKLSKAWC 87 567899999******************99852333146888887776666554 PP == domain 2 score: 11.2 bits; conditional E-value: 8.5e-05 RdRP_helical 12 eFeilFllnallhkgiivqkaldaelfklLeevpe 46 eF+i++ l ll++g v l++++++lL++ ++ FUN_000213-T1 308 EFKIIYALECLLSRGYKVRDRLSQKFYDLLQRASD 342 8*****************************99865 PP == domain 3 score: -3.6 bits; conditional E-value: 3.3 RdRP_helical 16 lFllnallhkgiivqk 31 lF++n+ l+ + ++ FUN_000213-T1 1054 LFRVNTRLSAKTDEKF 1069 6788887774333333 PP >> DUF7752 Domain of unknown function (DUF7752) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 6.7e-05 0.34 2 45 .. 1329 1375 .. 1328 1406 .. 0.82 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 6.7e-05 DUF7752 2 vkrypgLdkllffllkWaekhklf...eksplreehlclLliqfglg 45 v+r p L +ll ++++W+++ ++ ek l+ e+l++++i f+ + FUN_000213-T1 1329 VQRCPRLFHLLRIIMNWGRRRQINgyhEKLFLTDEQLAIIFITFCEK 1375 7899******************9954455789************865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1568 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 816 (0.0319436); expected 510.9 (0.02) Passed bias filter: 661 (0.0258759); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.55u 0.37s 00:00:00.92 Elapsed: 00:00:00.43 # Mc/sec: 14584.66 // Query: FUN_000213-T2 [L=1937] Description: FUN_000213 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-179 597.4 0.0 6.2e-179 596.9 0.0 1.2 1 RdRP RNA dependent RNA polymerase 1.7e-24 87.1 1.5 4.6e-24 85.8 1.5 1.7 1 RdRP_head RdRP, head domain 8.9e-08 32.4 6.4 3.4e-07 30.5 3.6 3.1 2 PH_met_RdRP Metazoan RdRP associated PH-like domain ------ inclusion threshold ------ 0.029 14.9 0.1 0.55 10.8 0.0 2.8 2 RdRP_helical RNA dependent RNA polymerase, helical domain 0.14 12.8 0.1 0.45 11.1 0.1 1.9 1 DUF7752 Domain of unknown function (DUF7752) Domain annotation for each model (and alignments): >> RdRP RNA dependent RNA polymerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 596.9 0.0 1.2e-182 6.2e-179 1 583 [. 412 985 .. 412 986 .. 0.90 Alignments for each domain: == domain 1 score: 596.9 bits; conditional E-value: 1.2e-182 RdRP 1 vtptrillegpeleksnrvlRrfkegsdrflrvqfpdedleq.rlnsevdseeevfervkkllkegikiagrkfeflafsnsqlrehsvwffapfe 95 +tpt+ +l +pel nrv+R + g+++ +r+ f+ded ++ + +++ +++++erv +ll++ i+i+grkfefla+snsqlr+h++w++a FUN_000213-T2 412 ITPTQRFLIPPELVAENRVIRDY--GHENAMRIAFRDEDFSKlSSTHREGLNDVLQERVMDLLSQHIEIGGRKFEFLACSNSQLRDHGAWLYAV-- 503 79*********************..**************996554455455*****************************************94.. PP RdRP 96 esgervtveeirkwlgdfsnieqsvaKyaaRlgqafSktratvvkveeee.i.veeipD..........evrngkkiyv..........ftDGvGk 169 +ge ++++ir++lg++++i ++va y++R+gq+fS+t+++ v+++ ee e+ipD + + f+DGvGk FUN_000213-T2 504 -EGE-HRAHDIRSSLGRLTEI-RCVATYVSRMGQCFSSTKEA-VTINIEEgFeNEQIPDvemefkdvffK--------CcqnwrsgtytFSDGVGK 587 .333.69**************.*******************5.4445555555899**975544444443........23555555555******* PP RdRP 170 iSrelarkiakelglkkeelPsafQiRlgGaKGvlavdkel...p.kdwielrpSmiKfeseeesrtLeivkaskkpkpayLnrqlIkiLedlgvp 261 iSr+lark+a++l+l +++Psa+QiR+gG+KG+la+d++l + ++ + r+Sm+Kf+s +r Lei+++sk++ +yLnrq I++L+ lgvp FUN_000213-T2 588 ISRALARKVADSLNL--DPIPSAYQIRFGGCKGMLAIDPSLphgNfREILLYRKSMRKFDST--HRVLEICETSKPN-LLYLNRQCIILLSGLGVP 678 ***************..69**********************765344468899******776..666********99.****************** PP RdRP 262 devflelleealeeleealkdaelaaelleksgdpaeleellaellkagfepkelkdpflrsllkllvkkklrelkekarIpvp..ksatllgvaD 355 d+vf+ l++e+l++l+++l +++a++ l++ p ++ ++l ++g++ + +pf+rsll +++k++l +l ++arI +p +++ l+gv+D FUN_000213-T2 679 DDVFIGLQDEMLRTLASILLFESVALDSLRRITIPGGMKF--TSLSRSGINVT--LEPFFRSLLLAVYKSRLGDLLRRARIAIPetHGRLLMGVMD 770 *****************************98877777765..57779999655..39***************************888********* PP RdRP 356 etgvLeegevfvqfssatve.eekektkllegkvlVaRnPalhpgDiqvvravdvpelrhlkdvvVFsqkGdrplpselsGGDlDGDlywviwdpe 450 etg L++g+vfv++s+ + + ++ + k+l+g+v++++nP+ hpgD++ ++avdv++l+hl+d++VF+ G+rp+p+e+sG+DlDGD+y+v+w + FUN_000213-T2 771 ETGSLQYGQVFVRYSKSVSQpGK--ELKTLDGRVVISKNPCFHPGDMRTFKAVDVEALHHLVDCIVFPAIGPRPHPNEMSGSDLDGDKYFVTWLDK 864 **************995444344..599999***************************************************************** PP RdRP 451 lefapakptneepadyeaakpkeldrevtvediadffveymksdvlGlianahlaiadqseegvkdekclkLaelhskaVDypKtGipvekkelpr 546 l p+ ++neep+d++a+++k+l+r+v+v+d+ +f+ +y+k+d+lG+ianahl++ad +++g+++++c++La++hs+aVD+pKtG+ + l++ FUN_000213-T2 865 LI--PT-RRNEEPMDFTAPEKKTLTRPVQVSDMIEFVSDYIKNDQLGIIANAHLVHADYNKDGIFSPECIQLAHMHSDAVDFPKTGKCPT---LSK 954 *5..55.68899******************************************************************************...999 PP RdRP 547 elkkpkekPdfkekekkekkkkkyyksekilGkLyre 583 el +p ++Pdf++k+ k+ yks++ilG+L+r+ FUN_000213-T2 955 EL-RPDQYPDFMMKTG-----KPQYKSNRILGRLFRK 985 99.7999*****6553.....367***********98 PP >> RdRP_head RdRP, head domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.8 1.5 8.9e-28 4.6e-24 3 136 .. 1008 1174 .. 1006 1186 .. 0.85 Alignments for each domain: == domain 1 score: 85.8 bits; conditional E-value: 8.9e-28 RdRP_head 3 dedlevpgfedfleeakawkenYdekLtqlmdyYrvkteeeiltGiillllkrdskkqg.....kdriklavneLrkea..............a 77 dedl+v g+e +le+a+a +++Y++kL lm++Y+ k+e e++tG++ ++ r s k + ++ i+++ Lr ++ + FUN_000213-T2 1008 DEDLKVRGYERYLEDAEAARKHYNAKLEGLMSLYGLKNEGEVITGCLFRVNTRLSAKTDekfevAQMIQASLATLRAKTredfyaefggeeavM 1101 89*********************************************55555544444444447999***********9999999999999999 PP RdRP_head 78 seFeeskedeenlekkAsAwYqvtYhpairekkl..............aflsFaWvagdvLlrikaesakrke 136 eFee ++ +++ +kAsAwY vtY++ + + +sF+Wv+ + L++ik ++ ++ FUN_000213-T2 1102 EEFEENESFGDEVMMKASAWYMVTYDQVDQTSGSsqrdyqtadarteiQLISFPWVVDRILAEIKDMKQEERQ 1174 999999999999**************866554445799***************************96553333 PP >> PH_met_RdRP Metazoan RdRP associated PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 3.6 6.7e-11 3.4e-07 8 203 .. 121 277 .. 116 291 .. 0.78 2 ? 0.1 0.0 0.14 6.9e+02 14 53 .. 1664 1702 .. 1658 1713 .. 0.71 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 6.7e-11 PH_met_RdRP 8 ipleaiafGNilnggtFlnhwevsfpeetnseklqellkvlrelrkadikspmladFeHDrriltvrFavreeykkreveesnekgleeavyqlkv 103 ++ +++ fG+++n+gt++ hw+ + ++ k ++ ++++FeHD ++l++ F r+ ++ + +++++ FUN_000213-T2 121 LRANSFGFGSFFNRGTYIEHWSSQD--DCLFIK----------------ENHIQIEFEHDAKQLVISFFERDDTQ------------VFKEVRIEM 186 67799*****************994..455443................578****************9998722............45679**** PP PH_met_RdRP 104 rynsIrr.iivdle..dekgedrvriyfqlnyPpeirrfrkkknkkgkkklesegkRvlswpegdrkedeesseeaiseSpvfclefkeed...sd 193 y + +++d++ + + ++++++y+ l++Pp++ + k + ++++kRv + + + +e++ ++v+cl+f+e+ ++ FUN_000213-T2 187 DYRHLETyVVIDNNsdQTSPQKTIKLYIPLQFPPKVFQEVKLGE-------YTNYKRVTHFLK--------CCREVLGSCSVLCLCFPENWqenKA 267 ******9667799976555778899**********988555554.......467888775555........5799999999999999987522234 PP PH_met_RdRP 194 eelydilsRL 203 + +++RL FUN_000213-T2 268 DSPSALIARL 277 4566677776 PP == domain 2 score: 0.1 bits; conditional E-value: 0.14 PH_met_RdRP 14 afGNilnggtFlnhwevsfpeetnseklqellkvlrelrk 53 fG+i+ ++ l+h v + e+t s++ + ++ + +k FUN_000213-T2 1664 EFGSIYAENVMLVHSRVREVEDTFSKSA-DPRNQSGKANK 1702 7****************99999887764.44444333333 PP >> RdRP_helical RNA dependent RNA polymerase, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.27 1.4e+03 28 78 .. 35 87 .. 31 90 .. 0.74 2 ? 10.8 0.0 0.00011 0.55 12 46 .. 308 342 .. 305 347 .. 0.93 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.27 RdRP_helical 28 ivqkaldaelfklLeevpeevsvdilrklkk.lsm.vcyeaavwlkleqksia 78 +k+l + f+ Lee ++ ++ +r+ k l+ +++a+++ + +k + FUN_000213-T2 35 GDFKHLLRRYFQVLEEPSKPTNTGNIRNIKFtLKDaKMFGKAQFFEKLSKAWC 87 567899999******************99852333146888887776666554 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00011 RdRP_helical 12 eFeilFllnallhkgiivqkaldaelfklLeevpe 46 eF+i++ l ll++g v l++++++lL++ ++ FUN_000213-T2 308 EFKIIYALECLLSRGYKVRDRLSQKFYDLLQRASD 342 8*****************************99865 PP >> DUF7752 Domain of unknown function (DUF7752) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 8.8e-05 0.45 2 45 .. 1329 1375 .. 1328 1405 .. 0.82 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8.8e-05 DUF7752 2 vkrypgLdkllffllkWaekhklf...eksplreehlclLliqfglg 45 v+r p L +ll ++++W+++ ++ ek l+ e+l++++i f+ + FUN_000213-T2 1329 VQRCPRLFHLLRIIMNWGRRRQINgyhEKLFLTDEQLAIIFITFCEK 1375 7899******************9954455789************865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1937 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 822 (0.0321785); expected 510.9 (0.02) Passed bias filter: 648 (0.025367); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.59u 0.38s 00:00:00.97 Elapsed: 00:00:00.43 # Mc/sec: 17996.34 // Query: FUN_000215-T1 [L=991] Description: FUN_000215 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-69 234.9 0.0 3.7e-69 234.1 0.0 1.4 1 ERAP1_C ERAP1-like C-terminal domain 2.6e-69 233.7 0.3 5.1e-69 232.7 0.3 1.5 1 Peptidase_M1 Peptidase family M1 domain 2.7e-50 171.6 1.4 5.8e-50 170.5 0.5 1.9 2 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.12 13.9 0.1 0.26 12.8 0.1 1.5 1 YxzE YxzE-like putative bacteriocin 0.2 12.0 0.0 0.39 11.0 0.0 1.4 1 SP_C-Propep Surfactant protein C, N terminal propeptide Domain annotation for each model (and alignments): >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 234.1 0.0 7.2e-73 3.7e-69 1 317 [. 640 959 .. 640 960 .. 0.95 Alignments for each domain: == domain 1 score: 234.1 bits; conditional E-value: 7.2e-73 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlkslls.ed 93 w+k N ++tG+yrvnY+ +++ l++ql+ +k++ dRaglidd+++lara+ l+ + l+l yl++E++y+++ +a++ l+++ +++ + FUN_000215-T1 640 WIKGNIGQTGFYRVNYEIGNWKILTTQLKfnHKIFNDTDRAGLIDDSYNLARANLLNHTIPLSLSV-YLTKEEDYIPLVTAMAELKQIIKIVPsTR 734 9*************************999************************************9.999*********************98566 PP ERAP1_C 94 pvyealkaflrkllsplleklgweekpg.eshldqqlrslllsaacsagdeevvaeakklfeawlegddsa.ippdlrwavlcaavanggeaewda 187 pvy+ l++f+ l ++ ++klg e g +h + + r l+l++ c ag ++++ + +++f++w++++ ++ i p l+ v+ ++v +ggeaewd+ FUN_000215-T1 735 PVYPYLQKFIEYLTKEQFDKLGM-E--GtGDHFTWMKRGLILESNCLAGGASCLRNITRMFNQWMNDPIKNaIAPHLKYLVYYIGVMRGGEAEWDF 827 7*********************8.5..3379**********************************9988777************************ PP ERAP1_C 188 llerykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlagl.asnpagrelawdfvkenwdelekrlgggs.slgrlvkglt 281 ++e++k++++ s+k a+ +ala +++p+l+er+l+++ld +++ + l+ ++ ++ sn +g ++w+f++ n+d++++ lg+++ +l ++ + FUN_000215-T1 828 VFEQFKSANV-SDKSALHYALAGSQEPWLIERYLKYSLDLSKIDKSYLTNAFYYVaDSNAVGTNVVWNFLQLNFDRISNLLGSPQvTLKTFTPHVS 922 *****99999.***************************9999*************9999***********************9999********** PP ERAP1_C 282 psfsteeeldeveaFfadk.dtpglrralaqaletir 317 ++fst+ +l+++e+ ++ + + +++qa+e+++ FUN_000215-T1 923 SRFSTDYQLKQLEDSVKRVmKDETPPWTVNQAIERVK 959 **************99988555556699999999987 PP >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 232.7 0.3 9.9e-73 5.1e-69 1 218 [] 335 553 .. 335 553 .. 0.97 Alignments for each domain: == domain 1 score: 232.7 bits; conditional E-value: 9.9e-73 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 yalevt +++++fe+ f v+Y+l k+d valp f ++MEnwgli y+e+l+ll + +s+++++aHE+ HqWfGn+Vtm+wW+dlwLnE FUN_000215-T1 335 YALEVTNQTMMYFEKFFGVPYSLSKSDGVALPAFGPAGMENWGLIKYKERLVLLR----EGMTSQSITTLVAHEVGHQWFGNIVTMDWWTDLWLNE 426 89****************************************************9....5566799****************************** PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfa+y++++ ++++ pew+ +++++ v + l D l+ssh ++ v +++ i e+Fd isY KG s+l ml+++lg+e f++g+k+Yl+k++++ FUN_000215-T1 427 GFATYVSAVATQHIRPEWHSIPQFIVNYVFNSLDVDGLQSSHAVRIPVIDPQKILEIFDIISYRKGGSILFMLHNFLGDEIFRDGVKRYLTKHAFG 522 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasg.....kdvkslmdtw 218 na+t+dlwda++ea + +d++++m+t+ FUN_000215-T1 523 NAETKDLWDAMTEAIQaagktTDIRKMMNTF 553 *************877778899******986 PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.5 0.5 1.1e-53 5.8e-50 1 186 [] 117 300 .. 117 300 .. 0.96 2 ? -1.1 0.0 0.49 2.5e+03 100 122 .. 647 667 .. 640 671 .. 0.84 Alignments for each domain: == domain 1 score: 170.5 bits; conditional E-value: 1.1e-53 Peptidase_M1_N 1 vpehYdldlkinlkektfkGsvtitlqlknatssivlnakeleikkvslsaevasesvkvdfkveqkdeekltiklpeslqqtssvtLeieysge 95 +p+hY++ l+i+l++ f+G+v+i ++++ ts i l+++++++ + ++++++ e+++v+ ++ ++++ l+i+l+++l+ +++++ ++eysg+ FUN_000215-T1 117 KPSHYNIILSIDLTKPNFNGTVSIWIKISIITSYILLHTSNMNV-TLVEVKKESGEQIPVKRYFDFDKNQFLVIELESPLD-QGTYITTVEYSGK 209 69******************************************.5555568899999********************999.************* PP Peptidase_M1_N 96 lndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpviesekledgkkitkFeetpkmstYL 186 ++ +l+Glyks+Y d +g + ++a+Tqfe+ AR+afPcfDeP+ Katf+++i ++ + + lSNmp ++ ++e g k+++Fe+++kmstYL FUN_000215-T1 210 YSADLRGLYKSSYRDkNGVESFFAATQFEPLRARRAFPCFDEPALKATFNVTIVHNPKLISLSNMPLYQTYEKE-GFKYDRFEKSVKMSTYL 300 ***************99999************************************************888875.9***************9 PP == domain 2 score: -1.1 bits; conditional E-value: 0.49 Peptidase_M1_N 100 laGlykstYtdkgekkvvavTqf 122 +G+y+ +Y+ + k +++Tq+ FUN_000215-T1 647 QTGFYRVNYEIGNWK--ILTTQL 667 58********99888..889986 PP >> YxzE YxzE-like putative bacteriocin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 5.1e-05 0.26 3 34 .. 42 73 .. 40 87 .. 0.78 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 5.1e-05 YxzE 3 livllilvfiliiiilavltsskskkkkkrss 34 +iv++il++++iii+la++ ++++k+++ + FUN_000215-T1 42 AIVIFILILVIIIIVLAAVLGHERSKHREEIK 73 58888999999999999999999999988766 PP >> SP_C-Propep Surfactant protein C, N terminal propeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 7.6e-05 0.39 35 71 .. 37 72 .. 5 84 .. 0.79 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 7.6e-05 SP_C-Propep 35 nlkrllivvvvvvlvvvvvlgallmglhmsqkhtemv 71 ++k + iv+ +++lv+++++ a ++g s kh e + FUN_000215-T1 37 KIKLIAIVIFILILVIIIIVLAAVLGHERS-KHREEI 72 688889999999999999999999996655.666554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (991 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1388 (0.0543355); expected 510.9 (0.02) Passed bias filter: 988 (0.0386768); expected 510.9 (0.02) Passed Vit filter: 113 (0.00442357); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.49u 0.37s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 9482.67 // Query: FUN_000216-T1 [L=548] Description: FUN_000216 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-05 23.6 0.9 0.7 10.6 0.0 3.1 3 TPR_12 Tetratricopeptide repeat 6.6e-05 23.2 0.4 10 7.1 0.0 3.8 3 TPR_2 Tetratricopeptide repeat ------ inclusion threshold ------ 0.014 15.7 1.7 21 5.6 0.0 3.6 3 TPR_1 Tetratricopeptide repeat 0.097 13.4 2.3 47 5.0 0.2 3.6 3 TPR_8 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.49 3.1e+03 12 25 .. 267 280 .. 257 282 .. 0.75 2 ! 10.6 0.0 0.00011 0.7 51 76 .. 307 332 .. 299 333 .. 0.89 3 ! 9.6 0.1 0.00022 1.4 9 37 .. 455 483 .. 449 506 .. 0.88 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.49 TPR_12 12 vlrrlgrydeAlel 25 +++++g+++++ ++ FUN_000216-T1 267 LYYQMGNLEKCKKY 280 56889999988776 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00011 TPR_12 51 LgrlylalgdyeeAlelleqaleiae 76 L+ +y ++gd+ +A+elle + e++e FUN_000216-T1 307 LSGAYKQQGDFVKAEELLESSTEMLE 332 667899*****************998 PP == domain 3 score: 9.6 bits; conditional E-value: 0.00022 TPR_12 9 lAavlrrlgrydeAlellekalelaerll 37 +++vl g+y+e ++ +al++ae+l FUN_000216-T1 455 VGDVLTMKGEYEEGISAVSEALAVAEELQ 483 699**********************9984 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.1 0.1 0.0069 44 9 25 .. 266 282 .. 265 288 .. 0.84 2 ! 6.6 0.0 0.0022 14 7 25 .. 307 325 .. 302 331 .. 0.84 3 ! 7.1 0.0 0.0016 10 4 31 .. 452 479 .. 449 482 .. 0.88 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0069 TPR_2 9 layyklgdyeeAleaye 25 +yy++g++e+++++ e FUN_000216-T1 266 VLYYQMGNLEKCKKYGE 282 58***********9966 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0022 TPR_2 7 lGlayyklgdyeeAleaye 25 l+ ay ++gd+ +A+e++e FUN_000216-T1 307 LSGAYKQQGDFVKAEELLE 325 5669************998 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0016 TPR_2 4 lynlGlayyklgdyeeAleayekAleld 31 +++ G+++ ++g+yee + a +Al+ + FUN_000216-T1 452 CCAVGDVLTMKGEYEEGISAVSEALAVA 479 67889********************976 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.3 0.0098 63 10 23 .. 267 280 .. 266 280 .. 0.89 2 ? 5.6 0.0 0.0032 21 10 25 .. 310 325 .. 310 330 .. 0.88 3 ? 2.6 0.0 0.03 1.9e+02 8 31 .. 456 479 .. 451 482 .. 0.85 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.0098 TPR_1 10 ayfklgkydeAley 23 +y+++g+++++ +y FUN_000216-T1 267 LYYQMGNLEKCKKY 280 8*********9887 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0032 TPR_1 10 ayfklgkydeAleyye 25 ay ++g++ +A+e e FUN_000216-T1 310 AYKQQGDFVKAEELLE 325 7***********9876 PP == domain 3 score: 2.6 bits; conditional E-value: 0.03 TPR_1 8 GnayfklgkydeAleyyekALeln 31 G ++ +g+y+e + + ++AL + FUN_000216-T1 456 GDVLTMKGEYEEGISAVSEALAVA 479 778999**********99999876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.2 0.0073 47 9 23 .. 266 280 .. 259 281 .. 0.87 2 ? 3.9 0.1 0.017 1.1e+02 7 29 .. 307 329 .. 302 330 .. 0.86 3 ? 1.6 0.0 0.093 5.9e+02 4 31 .. 452 479 .. 451 481 .. 0.85 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0073 TPR_8 9 liylklgdyeeAkey 23 +y ++g++e+ k+y FUN_000216-T1 266 VLYYQMGNLEKCKKY 280 689**********98 PP == domain 2 score: 3.9 bits; conditional E-value: 0.017 TPR_8 7 lGliylklgdyeeAkeyyekale 29 l+ +y+++gd+ +A+e +e ++e FUN_000216-T1 307 LSGAYKQQGDFVKAEELLESSTE 329 5669************9998776 PP == domain 3 score: 1.6 bits; conditional E-value: 0.093 TPR_8 4 yynlGliylklgdyeeAkeyyekaleld 31 ++ G+++ +g+yee + + +al + FUN_000216-T1 452 CCAVGDVLTMKGEYEEGISAVSEALAVA 479 77889999999********999998766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (548 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 586 (0.0229399); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.54 # Mc/sec: 4137.82 // Query: FUN_000217-T1 [L=543] Description: FUN_000217 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0089 16.7 0.8 0.0089 16.7 0.8 2.6 2 FliJ Flagellar FliJ protein ------ inclusion threshold ------ 0.041 14.2 2.0 0.066 13.5 2.0 1.3 1 CALS1 Callose synthase 1 domain 0.043 14.4 1.5 0.043 14.4 1.5 3.1 3 Cep57_CLD_2 Centrosome localisation domain of PPC89 2.2 8.0 4.7 0.33 10.7 0.4 1.7 2 DUF4407 Domain of unknown function (DUF4407) Domain annotation for each model (and alignments): >> FliJ Flagellar FliJ protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 8.3 3.2 2e+04 12 67 .. 206 259 .. 187 309 .. 0.56 2 ! 16.7 0.8 1.4e-06 0.0089 1 53 [. 331 384 .. 331 387 .. 0.90 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 3.2 FliJ 12 qeleqaeekleeleeyreeyqqqlsgalqGlsaaelrnyqafisqldeaieqqqqe 67 l++++++ +el++ ++e ++q++ l++ + s++ +ai++q++ FUN_000217-T1 206 LLLQEKRRHGAELNKLLNEMESQKELLH--TYELTLEHKDSIVSNITNAIQKQKER 259 2223333333333333333333333222..22333344444444444444444443 PP == domain 2 score: 16.7 bits; conditional E-value: 1.4e-06 FliJ 1 eeaarelaeaqqeleqaeekleeleeyreeyqqqlsgal.qGlsaaelrnyqaf 53 e+ +++l+ a +ele a++++++l ++r++y++ +++a+ +G+ a +l++ + f FUN_000217-T1 331 EDYENRLQTATRELEVARNEIARLHAERDQYEETMKKAFmRGVCALNLEAMSMF 384 56799**********************************999999888877766 PP >> CALS1 Callose synthase 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 2.0 1e-05 0.066 57 170 .. 238 355 .. 222 356 .. 0.78 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1e-05 CALS1 57 ldeeekkvveeifkeveesiekktllkefrlseLpslskklvkLlelLkeeeeedkkkkqvvnllqdilevvtrdimedgeslkde....dereql 148 + e+ ++v++i+++++++ e++++l+ f l +L + ++ + + + L +++ ++ ++++ + ++e ++ +e+ + k + + +e+ FUN_000217-T1 238 TLEHKDSIVSNITNAIQKQKERNEMLRAFTLWKLRHCDERRESFASKLARRHYNHVLQSRAWSAWRSVIESRWKQRVEKACQAKAQdvcvKLTEDY 333 33556689********************************************99999999999999999998888888876666552232344555 PP CALS1 149 faklnlklvkeeawkekikRLh 170 ++l++ + + e ++ i RLh FUN_000217-T1 334 ENRLQTATRELEVARNEIARLH 355 5566666667788888888888 PP >> Cep57_CLD_2 Centrosome localisation domain of PPC89 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 1.4 0.5 3.2e+03 45 62 .. 216 233 .. 207 241 .. 0.78 2 ? -2.1 0.8 0.92 5.9e+03 20 42 .. 254 287 .. 246 293 .. 0.57 3 ? 14.4 1.5 6.8e-06 0.043 9 43 .. 334 368 .. 331 371 .. 0.91 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.5 Cep57_CLD_2 45 leiqeLkaenealrkElk 62 e+++L +e e+ ++ l FUN_000217-T1 216 AELNKLLNEMESQKELLH 233 589999999998876555 PP == domain 2 score: -2.1 bits; conditional E-value: 0.92 Cep57_CLD_2 20 evheselkrLrr...........ERDsalrqLgv 42 +++ + +++Lr+ R+s++++L + FUN_000217-T1 254 QKQKERNEMLRAftlwklrhcdeRRESFASKLAR 287 5555555555554444444444346666666665 PP == domain 3 score: 14.4 bits; conditional E-value: 6.8e-06 Cep57_CLD_2 9 qnrLdsltrklevheselkrLrrERDsalrqLgvA 43 +nrL +tr+lev+ e++rL +ERD ++ A FUN_000217-T1 334 ENRLQTATRELEVARNEIARLHAERDQYEETMKKA 368 59*************************99877766 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.4 0.41 2.6e+03 189 212 .. 211 240 .. 183 288 .. 0.53 2 ? 10.7 0.4 5.1e-05 0.33 111 166 .. 312 367 .. 307 396 .. 0.86 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.41 DUF4407 189 keeeldaaqaelaalqak......ntakle 212 k+++ +++++ l++++++ + +le FUN_000217-T1 211 KRRHGAELNKLLNEMESQkellhtYELTLE 240 333333333333333333333333222222 PP == domain 2 score: 10.7 bits; conditional E-value: 5.1e-05 DUF4407 111 qeldeekneeadaakaqlaqalraelaelqaqiaalqaeidaaekeldelqkearc 166 q++++ +++a+++ +l+++++++l++++++++ +++ei+ +++e+d+ ++++++ FUN_000217-T1 312 QRVEKACQAKAQDVCVKLTEDYENRLQTATRELEVARNEIARLHAERDQYEETMKK 367 677888889999999999999****************************9998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (543 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1634 (0.0639656); expected 510.9 (0.02) Passed bias filter: 535 (0.0209434); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.44s 00:00:00.81 Elapsed: 00:00:00.48 # Mc/sec: 4526.06 // Query: FUN_000219-T1 [L=1237] Description: FUN_000219 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-19 69.9 7.6 2.3e-19 69.9 7.6 2.7 2 WSC WSC domain 4.2e-08 33.8 0.3 4.2e-08 33.8 0.3 2.3 2 SEA SEA domain ------ inclusion threshold ------ 1.8 8.9 7.2 2.9 8.3 2.9 2.6 2 DUF7436 Family of unknown function (DUF7436) 5.9 6.1 7.5 13 5.0 7.5 1.5 1 LMBR1 LMBR1-like membrane protein Domain annotation for each model (and alignments): >> WSC WSC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 2.7 0.2 1.3e+03 8 36 .. 202 230 .. 195 242 .. 0.72 2 ! 69.9 7.6 3.6e-23 2.3e-19 1 82 [] 614 692 .. 614 692 .. 0.94 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.2 WSC 8 ssessrlllassasssdmtvekCvaaCke 36 +++++++++++ ++++++t ++C ++C + FUN_000219-T1 202 TQDQQSQQQDAGNNNATQTQGNCERKCFT 230 44556666667778888899999999974 PP == domain 2 score: 69.9 bits; conditional E-value: 3.6e-23 WSC 1 ylGCysdssessrlllassasssdmtvekCvaaCkekgykyagleygkeCyCgnslpssskkaeeseCntsCsGdsselCGg 82 y+GC++d+ + + l++++++ +mt+e+Cv +Ck +gy++agl+yg+ C+Cgn++ ++ k+++++ C++ C Gd+++ CG+ FUN_000219-T1 614 YVGCFRDR--KPGRDLPKQFTKYEMTPEWCVGKCKLAGYSFAGLQYGYLCFCGNKYGKYGKADNSE-CSSLCFGDKTRNCGA 692 9*****99..6778888899999*************************************999776.*************95 PP >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.8 0.3 6.5e-12 4.2e-08 5 97 .. 475 560 .. 472 568 .. 0.87 2 ? -1.4 0.2 0.55 3.5e+03 66 88 .. 1133 1155 .. 1095 1172 .. 0.58 Alignments for each domain: == domain 1 score: 33.8 bits; conditional E-value: 6.5e-12 SEA 5 gsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspekgsvvvdvvlvfrfpstenaldreklieeileqkln 97 +s+++++ ++ +d+++psS++++ +s ++e++++++++ l++++++++v++ls e+ +v +++ l f +p ++l+ +i ++ l+ FUN_000219-T1 475 ASLRFKQ-NWHSDYRRPSSTKYRIFSTEVEKAIKDVYS---LDPNFKSVRVTSLSDEDMKVAANFELDFIQP---EDKALKRLAAAITNNYLQ 560 5666654.99***************************9...5*****************************9...667777777777777666 PP == domain 2 score: -1.4 bits; conditional E-value: 0.55 SEA 66 vvdvvlvfrfpstenaldrekli 88 vv v +++++ ++ d +k+ FUN_000219-T1 1133 VVKKVNELAQSIRQEVDDYKKTH 1155 33333333333344444444444 PP >> DUF7436 Family of unknown function (DUF7436) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 2.9 0.00045 2.9 12 94 .. 1060 1143 .. 1057 1152 .. 0.84 2 ? 1.7 0.1 0.048 3.1e+02 23 87 .. 1158 1222 .. 1148 1236 .. 0.74 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00045 DUF7436 12 GseeavdlllerlaaAdesvvavvgapyeq.adletleeeveafleeaeddvsVslllseevvdtlpeelrelladqsedvevR 94 G ++ + +++++++ e+v++ v + ye+ +l +l++ v+++ e++ +++ V +++v +++ e++r+++ ++ ++++ FUN_000219-T1 1060 GGDTQLTKMKDHVEKGAENVMSLVLDIYESkKTLANLQQIVQQLKEDVMQQMAVPAGQKDQVKNEIKETVRQTVVKKVNELAQS 1143 678889999****99999988777777765378999**********************************99998887665544 PP == domain 2 score: 1.7 bits; conditional E-value: 0.048 DUF7436 23 rlaaAdesvvavvgapyeqadletleeeveafleeaeddvsVslllseevvdtlpeelrelladq 87 ++A+e v a+++ p+ q ++++l++++ + + ++e++ + see+ + l e++++++ad FUN_000219-T1 1158 VSQQAKEAVAAILDIPVFQDKVKSLKSQIRKRAVAIEKEYKKAKRGSEELPSILKEHFKRNTADI 1222 56789999999999999999999999999988888888877777777777777777777666654 PP >> LMBR1 LMBR1-like membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 7.5 0.002 13 208 303 .. 1064 1167 .. 1045 1211 .. 0.84 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.002 LMBR1 208 klkeekeeaeeeledllkevkqlkesikesdplrkyleeile......kvPseiterlkseee..neeatekslaelhkqlikalqkkkrtekq 293 +l++ k++ e+ e++++ v + es+k ++l++ ++++ e vP+ ++++k+e + ++ k+++el +++++++ ++k+t++ FUN_000219-T1 1064 QLTKMKDHVEKGAENVMSLVLDIYESKKTLANLQQIVQQLKEdvmqqmAVPAGQKDQVKNEIKetVRQTVVKKVNELAQSIRQEVDDYKKTHQA 1157 567778888999999999999999999999988888888888888899999999999999888887788889********************** PP LMBR1 294 wkkllkkafe 303 ++ k+a++ FUN_000219-T1 1158 VSQQAKEAVA 1167 **99999932 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1237 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3096 (0.121198); expected 510.9 (0.02) Passed bias filter: 823 (0.0322177); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.55u 0.44s 00:00:00.99 Elapsed: 00:00:00.48 # Mc/sec: 10457.43 // Query: FUN_000220-T1 [L=689] Description: FUN_000220 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-36 125.0 0.7 1.3e-35 123.5 0.6 1.5 1 Lipoxygenase Lipoxygenase 5.2e-05 23.9 8.3 0.00011 22.8 8.3 1.6 1 EGF EGF-like domain ------ inclusion threshold ------ 0.63 11.1 6.5 2 9.5 4.7 2.5 1 hEGF Human growth factor-like EGF 1.4 9.4 6.4 11 6.5 0.1 3.7 4 Rsd_AlgQ Regulator of RNA polymerase sigma(70) subunit, 3.8 8.4 10.7 7.1 7.6 10.7 1.5 1 EGF_2 EGF-like domain Domain annotation for each model (and alignments): >> Lipoxygenase Lipoxygenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 123.5 0.6 2.5e-39 1.3e-35 138 561 .. 167 589 .. 115 614 .. 0.76 Alignments for each domain: == domain 1 score: 123.5 bits; conditional E-value: 2.5e-39 Lipoxygenase 138 yeegiklkkkklkeelkkklplpellkeilkaekeeellkfelPkvikedklawlrdeefaretlaGlnpvviellkefplkskldpevygd...q 230 e+ ++lk+ +e+ + + + ++ e++ +++++ + k++ + + +++d+ fa + +aG np+++ ++++ + ++ ++ + + FUN_000220-T1 167 LESRFTLKD-PRFHEIPTLIDF-AVVYETF-YKHHRKHSAMSALKLVPAVEENFFKDRCFADQRVAGANPLQLWRITDKEDDNGIQWKTLLEeklN 259 455555555.344555555555.3344444.23334556666677777888899**********************98887777776665441224 PP Lipoxygenase 231 esaiteehiekeleg...ltveealeekklfildyhD...lllP..ylkkineleetklyasrtllfl...kkdgt..LkplaieL.slPkkeeke 312 +s ee+ ++ l+ t+e+a+++ +++ y + + +P l++ + +++ +s lf +++g+ L p+ai++ s+P FUN_000220-T1 260 KSFDWEETFKAALSKgdeNTLEKAIDNGQIYAAIYPEldgVKMPkaLLHDTKFNHTVLQMSSPIALFAvieSEHGIkrLVPVAIQMdSTP------ 349 5666788888888533559************98775411256875457777766666667777667752223444333778888873444...... PP Lipoxygenase 313 evkkvftpaeeateawlWqlakahvlandsgyHqlvsHwlrtHavvEpfiiatnRqLsalHPiyklLkPhfrdtleinalaRqsLinagGiiEstf 408 +kv tp + W lak++v d +l++ l++H +++ ++ +s+ HPiy+l++ h+r +le n l +L + i + + FUN_000220-T1 350 -DSKVHTPID----GKDWFLAKSFVQRADFNSLHLIKKRLKAHLYLDAPCTLVEKYFSEYHPIYQLIRQHCRAALETNKLFEIKLFGRSAPIYKVL 440 .578999984....566******************************99999**********************************9998888777 PP Lipoxygenase 409 lpg.kyslelssaaYkklWrfdeeaLPadLikRglAvedpsaphglkLlieDYPyaaDGleiWsaikewvkeyvsiyYkedeavesDeElqawwke 503 + +le+ + Y+k +fd+ L +dL kRg+ +d+ + YPy DG+++++ + e+++ y++ yY++d++v+sD+Elq+ +e FUN_000220-T1 441 SVDySSALEMLNKEYEK-MTFDDLDLKNDLKKRGVDDTDK---------LTYYPYRDDGILLYEKLDEFADAYIDAYYDNDQEVTSDNELQELVNE 526 6541668********99.9***************865554.........356******************************************** PP Lipoxygenase 504 vrekgHa.Dkkd....epwwpklktkedLveilttiiWvasalhaavnfgqyayagylpnrpt 561 + g + D +++ k++ k+ L ++ltt++W +++haav + +y+g++pn p FUN_000220-T1 527 LSADGKQgDFGGkgmvKEFPAKIEDKATLRKVLTTLLWAFTGQHAAVTYPILEYGGFVPNAPH 589 **99975244331111345568999***********************************996 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 8.3 2.2e-08 0.00011 1 30 [. 44 75 .. 44 76 .. 0.90 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 2.2e-08 EGF 1 CspnpCsngGtCvdtp..rggytCiCpeGytG 30 C+pnpC+ngGtC + +gy C+C+ + G FUN_000220-T1 44 CKPNPCKNGGTCSRDYnlIDGYRCDCADDFGG 75 ************776679********998876 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 4.7 0.0004 2 1 19 [. 49 70 .. 49 73 .. 0.81 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0004 hEGF 1 ClNGGtCv.d..gvngykCqCp 19 C+NGGtC+ d +++gy+C C FUN_000220-T1 49 CKNGGTCSrDynLIDGYRCDCA 70 *******864337899*****7 PP >> Rsd_AlgQ Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.57 2.9e+03 129 143 .. 161 175 .. 152 181 .. 0.85 2 ? -0.2 0.1 0.26 1.3e+03 48 88 .. 384 423 .. 366 475 .. 0.69 3 ? 3.3 0.2 0.021 1.1e+02 94 130 .. 492 529 .. 488 533 .. 0.88 4 ? 6.5 0.1 0.0022 11 74 112 .. 628 667 .. 625 672 .. 0.84 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.57 Rsd_AlgQ 129 sklgeaLeeRfelED 143 ++l + Le+Rf+l D FUN_000220-T1 161 ADLNKDLESRFTLKD 175 578999******998 PP == domain 2 score: -0.2 bits; conditional E-value: 0.26 Rsd_AlgQ 48 lpseeelqefcqllvDYvSaGhFevYeqlveeaeefgekel 88 l+++ l+ c l+ Y S+ h +Y+ + ++++++ e+++ FUN_000220-T1 384 LKAHLYLDAPCTLVEKYFSEYH-PIYQLIRQHCRAALETNK 423 5556667777888888999987.799999998888766653 PP == domain 3 score: 3.3 bits; conditional E-value: 0.021 Rsd_AlgQ 94 lypkieatTeaald.fndkyeeaadedeleeldedLsk 130 ly+k+++ +a +d ++d+ +e ++++el+el ++Ls+ FUN_000220-T1 492 LYEKLDEFADAYIDaYYDNDQEVTSDNELQELVNELSA 529 7999999999999758999999**************97 PP == domain 4 score: 6.5 bits; conditional E-value: 0.0022 Rsd_AlgQ 74 eqlveeaeefgeke.lelakelypkieatTeaaldfndky 112 +ql++ e+ + k+ + +++++++++++ T+ +l+ ndk FUN_000220-T1 628 DQLLDYSEKVEGKKgQVVIEKMFKELKTLTDDILKANDKR 667 5777777777776669999*******************96 PP >> EGF_2 EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 10.7 0.0014 7.1 1 32 [] 44 78 .. 44 78 .. 0.89 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0014 EGF_2 1 CsasgliCsgrGtCvnqcG.....kCkCdsgyqGatC 32 C+++ C+++GtC++ + +C+C + + G tC FUN_000220-T1 44 CKPN--PCKNGGTCSRDYNlidgyRCDCADDFGGFTC 78 7765..8********9999988888***999999999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (689 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 721 (0.0282247); expected 510.9 (0.02) Passed bias filter: 545 (0.0213349); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 6800.79 // Query: FUN_000221-T1 [L=1276] Description: FUN_000221 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.8e-12 45.1 91.6 9.8e-06 25.7 29.9 5.3 5 Collagen Collagen triple helix repeat (20 copies) Domain annotation for each model (and alignments): >> Collagen Collagen triple helix repeat (20 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.0 5.7 0.00026 6.7 8 57 .. 297 347 .. 293 352 .. 0.39 2 ! 9.7 5.0 3.9e-05 1 16 49 .. 384 417 .. 378 428 .. 0.35 3 ? -3.0 0.2 0.37 9.3e+03 29 33 .. 567 571 .. 557 575 .. 0.29 4 ! 25.7 29.9 3.8e-10 9.8e-06 4 59 .. 701 756 .. 699 760 .. 0.49 5 ! 24.4 21.9 9.7e-10 2.5e-05 4 50 .. 805 851 .. 800 861 .. 0.46 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.00026 Collagen 8 epGppGppGkrGepGeaG.ekGekGpaGekGppGaaGkpGapGekGeaGap 57 ++ +G++ ++Ge+Ge e+Ge+ ++G++ + G+ G++G + +Ge ++ FUN_000221-T1 297 SASLEGKTSASGESGEYSeESGESDESGSSDESGESGDSGYAEDSGETEES 347 333344444444444432123333344444444444444444444443333 PP == domain 2 score: 9.7 bits; conditional E-value: 3.9e-05 Collagen 16 GkrGepGeaGekGekGpaGekGppGaaGkpGapG 49 G++ ++Ge+G e+G++Ge+G+ G ++G+ G FUN_000221-T1 384 GESSASGESGDWEESGASGESGSSGDFEESGESG 417 2222222222222222222222222222222222 PP == domain 3 score: -3.0 bits; conditional E-value: 0.37 Collagen 29 ekGpa 33 e+G++ FUN_000221-T1 567 ESGES 571 11222 PP == domain 4 score: 25.7 bits; conditional E-value: 3.8e-10 Collagen 4 GepGepGppGppGkrGepGeaGekGekGpaGekGppGaaGkpGapGekGeaGapge 59 G +Ge+G++G + ++Ge+Ge+Ge+Ge+G++Ge+G+ G+ G++G+ Ge+Ge+G++ge FUN_000221-T1 701 GGSGESGESGGSAESGESGESGESGESGESGESGESGESGESGESGESGESGESGE 756 44455555555555555555555555555555555555555555555555555444 PP == domain 5 score: 24.4 bits; conditional E-value: 9.7e-10 Collagen 4 GepGepGppGppGkrGepGeaGekGekGpaGekGppGaaGkpGapGe 50 Ge+G++ ++G++G++Ge+Ge+Ge+G++G++Ge+G+ G+ G++G+ Ge FUN_000221-T1 805 GESGDSEESGESGESGESGESGESGQSGESGESGQGGESGESGQSGE 851 44444444444444444444444444444444444444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1276 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1912 (0.0748483); expected 510.9 (0.02) Passed bias filter: 512 (0.0200431); expected 510.9 (0.02) Passed Vit filter: 101 (0.00395381); expected 25.5 (0.001) Passed Fwd filter: 34 (0.00133098); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 1.09u 0.41s 00:00:01.50 Elapsed: 00:00:00.45 # Mc/sec: 11449.45 // Query: FUN_000222-T1 [L=465] Description: FUN_000222 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-07 30.5 8.9 3.7e-07 30.5 8.9 2.8 2 zf-RING_UBOX RING-type zinc-finger 2.9e-05 24.3 10.0 2.9e-05 24.3 10.0 3.2 3 zf-C3HC4 Zinc finger, C3HC4 type (RING fin 0.00012 22.6 16.1 0.002 18.6 10.0 3.3 3 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/X 0.00095 19.4 11.9 0.00095 19.4 11.9 3.2 4 zf-C3HC4_3 Zinc finger, C3HC4 type (RING fin 0.0014 18.9 13.8 0.0014 18.9 13.8 3.0 3 zf-C3HC4_2 Zinc finger, C3HC4 type (RING fin 0.0016 19.2 15.5 0.0016 19.2 15.5 3.5 3 zf-RING_2 Ring finger domain 0.0019 18.7 10.1 0.0019 18.7 10.1 3.0 4 zf-C3HC4_4 zinc finger of C3HC4-type, RING 0.0024 18.2 6.9 0.019 15.4 4.7 3.0 2 Prok-RING_4 Prokaryotic RING finger family 4 ------ inclusion threshold ------ 0.014 15.9 14.7 0.014 15.9 14.7 3.2 3 zf-RING_5 zinc-RING finger domain 0.042 14.7 0.3 0.15 12.9 0.0 2.1 2 Sas-6-like_oligomerization Sas-6-like, oligomerization domai 0.14 12.3 3.1 11 6.3 0.2 2.8 2 ZNF512_C2HC Zinc finger protein 512, C2HC zin Domain annotation for each model (and alignments): >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.1 1.1 2.5e+03 29 39 .] 83 93 .. 80 96 .. 0.79 2 ! 30.5 8.9 1.6e-10 3.7e-07 1 39 [] 327 367 .. 327 367 .. 0.94 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 1.1 zf-RING_UBOX 29 skkekgkikCP 39 +k+ +gki CP FUN_000222-T1 83 AKWTEGKIYCP 93 67888999998 PP == domain 2 score: 30.5 bits; conditional E-value: 1.6e-10 zf-RING_UBOX 1 CpICleeftdPlvl.pCGHtfCreCl..welskkekgkikCP 39 C+ICl++f +P + +C H+fC Cl + + +++g+i+CP FUN_000222-T1 327 CSICLDLFFEP-LKcSCEHVFCDPCLrqLNFRTGRRGTIRCP 367 ***********.5448************999**********9 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.2 3.2 7.5e+03 22 31 .. 15 24 .. 14 28 .. 0.73 2 ? 1.9 0.1 0.13 3e+02 28 40 .] 84 95 .. 77 95 .. 0.83 3 ! 24.3 10.0 1.3e-08 2.9e-05 1 40 [] 327 369 .. 327 369 .. 0.93 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 3.2 zf-C3HC4 22 CssCikslle 31 C++C +l + FUN_000222-T1 15 CRKCRITLFS 24 9999877766 PP == domain 2 score: 1.9 bits; conditional E-value: 0.13 zf-C3HC4 28 sllesnnvkCplC 40 +++e ++ +Cp+C FUN_000222-T1 84 KWTE-GKIYCPKC 95 5666.8899**** PP == domain 3 score: 24.3 bits; conditional E-value: 1.3e-08 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCikslle....snnvkCplC 40 C+iCl+ + ep+ C H fC +C+++l +++ CplC FUN_000222-T1 327 CSICLDLFFEPL-KCSCEHVFCDPCLRQLNFrtgrRGTIRCPLC 369 ************.***************998888777777**** PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 3.2 7.5e+03 22 33 .. 15 26 .. 13 37 .. 0.73 2 ! 6.0 0.0 0.0074 17 34 55 .. 78 99 .. 62 101 .. 0.82 3 ! 18.6 10.0 8.5e-07 0.002 1 56 [. 326 374 .. 326 375 .. 0.87 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 3.2 RING_XB3-XBAT31 22 CaqCalalcskk 33 C +C ++l s+k FUN_000222-T1 15 CRKCRITLFSSK 26 888888888776 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0074 RING_XB3-XBAT31 34 kkteaataskespaCPfCRssi 55 +++e+a+ +++++ CP C s+i FUN_000222-T1 78 ENIEEAKWTEGKIYCPKCKSRI 99 4677778889999******998 PP == domain 3 score: 18.6 bits; conditional E-value: 8.5e-07 RING_XB3-XBAT31 1 lCsiCferactieveeCgHqlCaqCalalcskkkkteaataskespaCPfCRssiv 56 +CsiC++ + +C+H +C C +l +++ CP+CR++++ FUN_000222-T1 326 CCSICLDLFFEPLKCSCEHVFCDPCLRQLNFRT-------GRRGTIRCPLCRKTVE 374 6*************************9987663.......3457899*****9985 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 2.6 6e+03 26 33 .. 15 22 .. 11 27 .. 0.69 2 ? 0.7 0.0 0.28 6.4e+02 37 46 .. 90 99 .. 83 102 .. 0.70 3 ! 19.4 11.9 4.1e-07 0.00095 2 48 .. 324 375 .. 323 376 .. 0.94 4 ? -3.5 0.2 5.8 1.3e+04 13 20 .. 428 435 .. 425 445 .. 0.59 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.6 zf-C3HC4_3 26 CeeCaekl 33 C++C +l FUN_000222-T1 15 CRKCRITL 22 77777666 PP == domain 2 score: 0.7 bits; conditional E-value: 0.28 zf-C3HC4_3 37 kkCpiCrqki 46 Cp C++ i FUN_000222-T1 90 IYCPKCKSRI 99 5688887776 PP == domain 3 score: 19.4 bits; conditional E-value: 4.1e-07 zf-C3HC4_3 2 eeeCviClerernvvllpCgHlclCeeCaeklr......kkkkCpiCrqkies 48 +++C iCl+ + + + C H+ +C C ++l+ + +Cp+Cr+ +e+ FUN_000222-T1 324 RHCCSICLDLFFEPLKCSCEHV-FCDPCLRQLNfrtgrrGTIRCPLCRKTVEN 375 689*******************.***********99999999*******9985 PP == domain 4 score: -3.5 bits; conditional E-value: 5.8 zf-C3HC4_3 13 rnvvllpC 20 + v lpC FUN_000222-T1 428 QRSVTLPC 435 56778888 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.2 5 1.2e+04 23 29 .. 15 21 .. 14 26 .. 0.73 2 ? -0.7 0.1 0.79 1.8e+03 36 40 .] 91 95 .. 83 99 .. 0.74 3 ! 18.9 13.8 6.1e-07 0.0014 2 40 .] 327 369 .. 326 369 .. 0.82 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 5 zf-C3HC4_2 23 CqkCilr 29 C+kC ++ FUN_000222-T1 15 CRKCRIT 21 9999776 PP == domain 2 score: -0.7 bits; conditional E-value: 0.79 zf-C3HC4_2 36 eCPlC 40 CP+C FUN_000222-T1 91 YCPKC 95 79999 PP == domain 3 score: 18.9 bits; conditional E-value: 6.1e-07 zf-C3HC4_2 2 CpiCldmlkdplvvtpCgHvfCqkCilr.aLeesn....eCPlC 40 C iCld++ +p C HvfC C+++ + + +CPlC FUN_000222-T1 327 CSICLDLFFEP-LKCSCEHVFCDPCLRQlNFRTGRrgtiRCPLC 369 ***********.888***********99756544322378**99 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.2 0.21 5e+02 32 44 .] 84 96 .. 82 98 .. 0.88 2 ! 19.2 15.5 6.8e-07 0.0016 2 44 .] 326 370 .. 325 370 .. 0.83 3 ? -2.9 0.1 5.1 1.2e+04 13 21 .. 427 435 .. 422 448 .. 0.64 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.21 zf-RING_2 32 kwlrtsstCPlCr 44 kw++ + CP C+ FUN_000222-T1 84 KWTEGKIYCPKCK 96 79999999****6 PP == domain 2 score: 19.2 bits; conditional E-value: 6.8e-07 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkw.lrtsst....CPlCr 44 C+iCl+ + e+ k+ C Hvf+ Cl+++ +rt ++ CPlCr FUN_000222-T1 326 CCSICLDLFFEPLKCS---CEHVFCDPCLRQLnFRTGRRgtirCPLCR 370 5*****9996655544...************9666666699******9 PP == domain 3 score: -2.9 bits; conditional E-value: 5.1 zf-RING_2 13 eekvivlpC 21 +++ ++lpC FUN_000222-T1 427 SQRSVTLPC 435 455567888 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 8.3 1.9e+04 21 24 .. 15 18 .. 12 27 .. 0.64 2 ? -1.8 0.1 2.1 4.9e+03 19 24 .. 90 95 .. 85 99 .. 0.63 3 ! 18.7 10.1 8.3e-07 0.0019 1 42 [] 327 369 .. 327 369 .. 0.88 4 ? -2.9 0.4 4.7 1.1e+04 21 26 .. 442 447 .. 429 456 .. 0.54 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 8.3 zf-C3HC4_4 21 ClsC 24 C++C FUN_000222-T1 15 CRKC 18 6666 PP == domain 2 score: -1.8 bits; conditional E-value: 2.1 zf-C3HC4_4 19 sfClsC 24 ++C +C FUN_000222-T1 90 IYCPKC 95 455555 PP == domain 3 score: 18.7 bits; conditional E-value: 8.3e-07 zf-C3HC4_4 1 CpvCldyLekPvsieCGhsfClsCisslqkepdges.llCplC 42 C +Cld++ +P C+h+fC C+ +l CplC FUN_000222-T1 327 CSICLDLFFEPLKCSCEHVFCDPCLRQLNFRTGRRGtIRCPLC 369 9************************999876655544899999 PP == domain 4 score: -2.9 bits; conditional E-value: 4.7 zf-C3HC4_4 21 ClsCis 26 C++ FUN_000222-T1 442 VCACVY 447 223444 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.21 4.9e+02 33 41 .. 92 100 .. 85 104 .. 0.83 2 ! 15.4 4.7 8e-06 0.019 1 44 [. 327 377 .. 327 379 .. 0.85 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.21 Prok-RING_4 33 CPiCrrrvd 41 CP C++r+ FUN_000222-T1 92 CPKCKSRIG 100 ******996 PP == domain 2 score: 15.4 bits; conditional E-value: 8e-06 Prok-RING_4 1 CvlcgreetkivlspCgHlvCkeCfdssdfs.a......CPiCrrrvdadd 44 C++c ++ +C+H+ C+ C + +f + CP+Cr+ v++ + FUN_000222-T1 327 CSICLDLFFEPLKCSCEHVFCDPCLRQLNFRtGrrgtirCPLCRKTVENLS 377 88999998999999***************9743677788******998765 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.2 1.6 3.7e+03 2 9 .. 15 22 .. 14 29 .. 0.64 2 ? -1.6 1.0 1.7 4e+03 2 7 .. 92 97 .. 88 113 .. 0.69 3 ? 15.9 14.7 5.9e-06 0.014 2 43 .] 327 371 .. 325 371 .. 0.95 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.6 zf-RING_5 2 CnkCfkel 9 C kC+ l FUN_000222-T1 15 CRKCRITL 22 88887666 PP == domain 2 score: -1.6 bits; conditional E-value: 1.7 zf-RING_5 2 CnkCfk 7 C+kC + FUN_000222-T1 92 CPKCKS 97 555544 PP == domain 3 score: 15.9 bits; conditional E-value: 5.9e-06 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll......eerqCpiCkk 43 C++C + + ++ sC H+fC+ Cl +l+ +Cp+C+k FUN_000222-T1 327 CSICLDLF---FEPLKCSCEHVFCDPCLRQLNfrtgrrGTIRCPLCRK 371 999*****...888889********************99*******97 PP >> Sas-6-like_oligomerization Sas-6-like, oligomerization domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 6.9 1.6e+04 7 21 .. 234 248 .. 230 259 .. 0.77 2 ? 12.9 0.0 6.4e-05 0.15 25 42 .. 384 401 .. 376 405 .. 0.89 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 6.9 Sas-6-like_oligomerization 7 keerdsasiqlaqcr 21 ++rd s q c FUN_000222-T1 234 MDNRDLRSDQADECN 248 588999999988885 PP == domain 2 score: 12.9 bits; conditional E-value: 6.4e-05 Sas-6-like_oligomerization 25 aelreqydkhllevqaqa 42 e+r+ ydkhll v+a++ FUN_000222-T1 384 NEIRNTYDKHLLRVRAKS 401 599***********9986 PP >> ZNF512_C2HC Zinc finger protein 512, C2HC zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.2 0.0046 11 11 20 .. 87 96 .. 81 98 .. 0.88 2 ? 5.3 0.3 0.0098 23 11 28 .. 361 374 .. 355 377 .. 0.83 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0046 ZNF512_C2HC 11 kgeVtCPtCk 20 g++ CP+Ck FUN_000222-T1 87 EGKIYCPKCK 96 59*******8 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0098 ZNF512_C2HC 11 kgeVtCPtCkvVsRktve 28 +g + CP C Rktve FUN_000222-T1 361 RGTIRCPLC----RKTVE 374 89*******....67776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (465 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1084 (0.0424349); expected 510.9 (0.02) Passed bias filter: 543 (0.0212566); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4448.96 // Query: FUN_000223-T1 [L=384] Description: FUN_000223 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-106 355.1 0.1 5.3e-106 354.3 0.1 1.4 1 CARME Carnosine N-methyltransferase 0.00091 19.5 0.4 0.0023 18.2 0.0 2.0 2 Methyltransf_23 Methyltransferase domain 0.0033 17.7 0.1 0.19 12.0 0.0 2.7 3 Methyltransf_31 Methyltransferase domain 0.0055 17.8 0.0 0.022 15.8 0.0 2.1 2 Methyltransf_11 Methyltransferase domain ------ inclusion threshold ------ 0.018 16.2 0.0 0.13 13.4 0.0 2.4 2 Methyltransf_25 Methyltransferase domain 0.026 15.7 0.0 0.12 13.6 0.0 2.2 2 Methyltransf_12 Methyltransferase domain 0.043 14.5 0.2 0.12 13.1 0.2 1.7 1 BLYB Borrelia hemolysin accessory protein 0.048 13.0 0.1 0.25 10.6 0.1 1.8 2 DUF674 Protein of unknown function (DUF674) 0.12 12.7 0.2 3.4 8.0 0.2 2.2 2 RhoGAP RhoGAP domain Domain annotation for each model (and alignments): >> CARME Carnosine N-methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 354.3 0.1 1.9e-109 5.3e-106 10 267 .. 127 383 .. 119 384 .] 0.98 Alignments for each domain: == domain 1 score: 354.3 bits; conditional E-value: 1.9e-109 CARME 10 ldlskvrstlkqivRdwsaegkeERealykpiieelkklfpseskerekvkilvPGaGlGrlayelatkgyqvegnEfsyfmllasefiLnavkee 105 d++kv +tlkq+vRdws egk+ER+a+ykpiiee+++l+p s r++++ilvPGaGlGrl++++a++g+ ++gnE+s +ml+as+f+Ln+ + FUN_000223-T1 127 FDMEKVLTTLKQFVRDWSDEGKSERDACYKPIIEEIEQLYPAMSYSRKDISILVPGAGLGRLMFDIAKLGFMCQGNEWSLYMLFASHFVLNRAPGT 222 79********************************************************************************************** PP CARME 106 nqitiypfvhsfsnqlsrddqlrsvkipDveplsklkrkknlsmaagdflevykeeeesydvvvtcfFiDtaeNvleYletiekvlkpgglwiNlG 201 ++ tiyp+vh+++n++s+ dq+r+v+ipDv+p+ + n+smaagdflevy+e+ + +d+vvtc+FiDta+Nv+ Y+e i+k+lkpgg+wiN+G FUN_000223-T1 223 YHTTIYPYVHQTCNNKSTADQVRPVSIPDVDPTD-VPSGLNFSMAAGDFLEVYTEK-DCWDCVVTCYFIDTAHNVIAYIENIAKILKPGGYWINFG 316 *********************************9.********************9.*************************************** PP CARME 202 PLlYhfedledevsielsleeilalakk.vgfkvlkeekeieskYltnkesmlqlkYklvffvlrke 267 PLlYhf+d+++e s+els+e+i+++ + + f ++ke ++i s+Y+ n++sml+l Y vffv+rk+ FUN_000223-T1 317 PLLYHFSDMANEWSVELSYEDIKRISTDyFKFDIIKEVTSIPSGYIENERSMLKLLYDNVFFVARKP 383 **************************9989**********************************986 PP >> Methyltransf_23 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.3 0.95 2.7e+03 147 147 .. 51 51 .. 14 89 .. 0.58 2 ! 18.2 0.0 8e-07 0.0023 78 115 .. 276 313 .. 171 347 .. 0.80 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.95 Methyltransf_23 147 a 147 a FUN_000223-T1 51 A 51 2 PP == domain 2 score: 18.2 bits; conditional E-value: 8e-07 Methyltransf_23 78 pagkydvIvlrevlehvkdppallrqiaallkpgGlll 115 +++ +d++v+ + +++ ++++a++++ia++lkpgG+ + FUN_000223-T1 276 EKDCWDCVVTCYFIDTAHNVIAYIENIAKILKPGGYWI 313 67799******************************965 PP >> Methyltransf_31 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 2.9 8.4e+03 117 137 .. 70 90 .. 56 107 .. 0.56 2 ? 2.8 0.0 0.046 1.3e+02 3 30 .. 174 200 .. 172 206 .. 0.86 3 ! 12.0 0.0 6.8e-05 0.19 55 108 .. 262 313 .. 258 354 .. 0.89 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 2.9 Methyltransf_31 117 elpaevkeeseeykecvegai 137 e+ ++k+ +++++c+e ++ FUN_000223-T1 70 EMLPHFKDHINKIMQCIEENQ 90 444555555555554443333 PP == domain 2 score: 2.8 bits; conditional E-value: 0.046 Methyltransf_31 3 kglkvLDlGCGtGrlsfelaeelgpnae 30 k+ ++L G+G Grl+f++a +lg++++ FUN_000223-T1 174 KDISILVPGAGLGRLMFDIA-KLGFMCQ 200 67788889************.8888775 PP == domain 3 score: 12.0 bits; conditional E-value: 6.8e-05 Methyltransf_31 55 nvkFeqgdieelpesledekfDviisnevlnavpdpdkvleeiervlkpggill 108 n+++ +gd++e e+++ D +++ + ++++ + +++e+i ++lkpgg+ + FUN_000223-T1 262 NFSMAAGDFLEVY--TEKDCWDCVVTCYFIDTAHNVIAYIENIAKILKPGGYWI 313 899********88..678********9999*********************976 PP >> Methyltransf_11 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 1.8 5.1e+03 3 31 .. 181 209 .. 179 244 .. 0.80 2 ! 15.8 0.0 7.9e-06 0.022 44 93 .. 263 312 .. 222 314 .. 0.86 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.8 Methyltransf_11 3 vGcGtGllaealarlgarvtgvDlspeml 31 G+G G+l+ +a+lg + g + s +ml FUN_000223-T1 181 PGAGLGRLMFDIAKLGFMCQGNEWSLYML 209 58999999999999998888888888887 PP == domain 2 score: 15.8 bits; conditional E-value: 7.9e-06 Methyltransf_11 44 vefvqadaedlpfpdesfDlvlssevlhhvedpekalreiaRvLkpgGll 93 +++ +d+ ++ + + D+v+ ++++ +++ +++++ia++LkpgG+ FUN_000223-T1 263 FSMAAGDFLEVYTEKDCWDCVVTCYFIDTAHNVIAYIENIAKILKPGGYW 312 5667889999988999********************************96 PP >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 1.8 5.1e+03 2 22 .. 179 197 .. 178 213 .. 0.75 2 ? 13.4 0.0 4.6e-05 0.13 44 97 .] 259 310 .. 252 310 .. 0.88 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.8 Methyltransf_25 2 LdlGcGtGrlalelakrlgea 22 L G+G Grl+ +ak + FUN_000223-T1 179 LVPGAGLGRLMFDIAKLG--F 197 66699********99984..4 PP == domain 2 score: 13.4 bits; conditional E-value: 4.6e-05 Methyltransf_25 44 eglnvefvqgdaedlpfedgsfdlvvssgalhhlsdedleaalaeiarvLkpgG 97 +gln+++ gd+ ++ e++ d+vv+++ + +++ a++++ia++LkpgG FUN_000223-T1 259 SGLNFSMAAGDFLEVYTEKDCWDCVVTCYFIDTA--HNVIAYIENIAKILKPGG 310 57899999*******99**********8666654..47889************9 PP >> Methyltransf_12 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 3.1 8.7e+03 4 17 .. 182 195 .. 181 206 .. 0.89 2 ? 13.6 0.0 4.3e-05 0.12 65 97 .. 279 311 .. 240 312 .. 0.88 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 3.1 Methyltransf_12 4 GcGtGallrallea 17 G+G G+l++ +++ FUN_000223-T1 182 GAGLGRLMFDIAKL 195 99*******99986 PP == domain 2 score: 13.6 bits; conditional E-value: 4.3e-05 Methyltransf_12 65 sfDvvvasnvlhhladleevlrnlrrlLkpgGv 97 +D+vv ++++ ++ + ++n+++ LkpgG+ FUN_000223-T1 279 CWDCVVTCYFIDTAHNVIAYIENIAKILKPGGY 311 68******************************6 PP >> BLYB Borrelia hemolysin accessory protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.2 4.1e-05 0.12 21 85 .. 23 90 .. 18 99 .. 0.76 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 4.1e-05 BLYB 21 ksdteiDelfqkgfkkvidlykyykkiYtkslkklesaes..kkivke.ledilekiaklidainsDk 85 +++te D+l ++ f kv++ +++yk+ ++l+++ + + ++ +e l + ++i+k+++ i+ ++ FUN_000223-T1 23 HMETEEDKLERQHFWKVVEAFHFYKHFSARKLQRIKDNYTflPRTHREmLPHFKDHINKIMQCIEENQ 90 689******************9999999*******987664434444414556666777777666655 PP >> DUF674 Protein of unknown function (DUF674) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 8.8e-05 0.25 330 388 .. 62 122 .. 42 141 .. 0.75 2 ? -0.2 0.0 0.17 4.8e+02 64 103 .. 335 374 .. 330 376 .. 0.91 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 8.8e-05 DUF674 330 s...llskkvlphyykcsqkqlleveeeepevyyslvsskskeklkeeakk.vkvklvdpkse 388 + +++++lph+ k + +++++++ee++++ ++vs+ + e++++ ++ v+++ vdp s+ FUN_000223-T1 62 TflpRTHREMLPHF-KDHINKIMQCIEENQNFLNRIVSH-TGEMFENRDHTrVPMNPVDPASQ 122 244467899*****.555899999999999*99999999.666666665556********976 PP == domain 2 score: -0.2 bits; conditional E-value: 0.17 DUF674 64 YkSVedleievfeteaCkqmLLyPrsvkeakcrklKlnid 103 Y+ ++++++++f+ ++ k++ P e++ +lKl d FUN_000223-T1 335 YEDIKRISTDYFKFDIIKEVTSIPSGYIENERSMLKLLYD 374 89999*******************************9766 PP >> RhoGAP RhoGAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.2 0.0012 3.4 90 129 .. 51 90 .. 31 96 .. 0.85 2 ? 2.3 0.0 0.071 2e+02 47 68 .. 123 144 .. 97 146 .. 0.80 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0012 RhoGAP 90 eerlealkellekLPkanretLryLlehLkrvaknseknk 129 +l+++k+ + LP+++re+L + +h++++ ++ e+n+ FUN_000223-T1 51 ARKLQRIKDNYTFLPRTHREMLPHFKDHINKIMQCIEENQ 90 4788999999999**********************99986 PP == domain 2 score: 2.3 bits; conditional E-value: 0.071 RhoGAP 47 dleeedvhdvaslLKlflrelp 68 ++ +d++ v ++LK+f r+ FUN_000223-T1 123 PISGFDMEKVLTTLKQFVRDWS 144 77899**************865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (384 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1024 (0.0400861); expected 510.9 (0.02) Passed bias filter: 802 (0.0313956); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3742.61 // Query: FUN_000224-T1 [L=891] Description: FUN_000224 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.8e-11 42.5 15.6 8.8e-11 42.5 15.6 2.9 2 KIAA1328 Uncharacterised protein KIAA1328 ------ inclusion threshold ------ 6.2 6.2 9.6 13 5.1 9.6 1.4 1 Piezo_TM25-28 Piezo TM25-28 Domain annotation for each model (and alignments): >> KIAA1328 Uncharacterised protein KIAA1328 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.5 15.6 6.9e-15 8.8e-11 2 75 .. 123 196 .. 122 390 .. 0.63 2 ? -6.1 12.7 2 2.6e+04 285 321 .. 455 492 .. 413 540 .. 0.66 Alignments for each domain: == domain 1 score: 42.5 bits; conditional E-value: 6.9e-15 KIAA1328 2 LCleDkRRianLikeLaRvseekevteeRLkaeqesFekkirqLeeqneLiikereaLqlqYReCqeLLsLYqk 75 L + Dk+R+anL+keLa+v ee+ eeRL+ e ++F+ ++ L e + ++ke++ L++ + e q LL Yq FUN_000224-T1 123 LNPQDKKRVANLVKELAKVGEERINAEERLQIERKAFDERLVILQEEYDAVLKEKQYLKKRFLELQALLVKYQV 196 7799******************************************************************9994 PP == domain 2 score: -6.1 bits; conditional E-value: 2 KIAA1328 285 qkLllqkmeLeiekerLq..hLLaqqetkLLlkqqqLhq 321 +L lq+ +e+ k +Lq + L q + L kq+q +q FUN_000224-T1 455 LQLQLQQQQIELQKQQLQlqQQLQ-QVEALQQKQEQQRQ 492 344444444444444433103332.22233333333322 PP >> Piezo_TM25-28 Piezo TM25-28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 9.6 0.001 13 177 262 .. 439 519 .. 431 537 .. 0.51 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.001 Piezo_TM25-28 177 vadlkaskllasrGaelfeasivksvkarkeeekksleqlkrqmerikakqkkvkeakesseseeeekepeeeeekaeeekekkek 262 a+l a l +r +el + ++++++ +k ql++q++++ a q+k+++++++ e + +e+ ++ + ek+++e+ + ++ FUN_000224-T1 439 SAELDAVYRLYCREYELQLQLQQQQIEL-----QKQQLQLQQQLQQVEALQQKQEQQRQQDEGQFKEQPQHLKPEKKQQEQRQVRE 519 5666666666667666655554444444.....34445666666666666666666666554443222222222222222222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (891 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2771 (0.108475); expected 510.9 (0.02) Passed bias filter: 758 (0.0296731); expected 510.9 (0.02) Passed Vit filter: 113 (0.00442357); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.46u 0.41s 00:00:00.87 Elapsed: 00:00:00.42 # Mc/sec: 8565.76 // Query: FUN_000224-T2 [L=847] Description: FUN_000224 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-11 43.1 15.1 5.8e-11 43.1 15.1 2.9 2 KIAA1328 Uncharacterised protein KIAA1328 ------ inclusion threshold ------ 5.7 6.3 9.6 13 5.2 9.6 1.5 1 Piezo_TM25-28 Piezo TM25-28 Domain annotation for each model (and alignments): >> KIAA1328 Uncharacterised protein KIAA1328 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.1 15.1 4.6e-15 5.8e-11 2 75 .. 123 196 .. 122 392 .. 0.62 2 ? -6.2 13.0 2 2.6e+04 285 321 .. 455 492 .. 414 540 .. 0.66 Alignments for each domain: == domain 1 score: 43.1 bits; conditional E-value: 4.6e-15 KIAA1328 2 LCleDkRRianLikeLaRvseekevteeRLkaeqesFekkirqLeeqneLiikereaLqlqYReCqeLLsLYqk 75 L + Dk+R+anL+keLa+v ee+ eeRL+ e ++F+ ++ L e + ++ke++ L++ + e q LL Yq FUN_000224-T2 123 LNPQDKKRVANLVKELAKVGEERINAEERLQIERKAFDERLVILQEEYDAVLKEKQYLKKRFLELQALLVKYQV 196 7799******************************************************************9994 PP == domain 2 score: -6.2 bits; conditional E-value: 2 KIAA1328 285 qkLllqkmeLeiekerLq..hLLaqqetkLLlkqqqLhq 321 +L lq+ +e+ k +Lq + L q + L kq+q +q FUN_000224-T2 455 LQLQLQQQQIELQKQQLQlqQQLQ-QVEALQQKQEQQRQ 492 344444444444444433103332.22233333333322 PP >> Piezo_TM25-28 Piezo TM25-28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 9.6 0.00098 13 177 262 .. 439 519 .. 431 537 .. 0.51 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.00098 Piezo_TM25-28 177 vadlkaskllasrGaelfeasivksvkarkeeekksleqlkrqmerikakqkkvkeakesseseeeekepeeeeekaeeekekkek 262 a+l a l +r +el + ++++++ +k ql++q++++ a q+k+++++++ e + +e+ ++ + ek+++e+ + ++ FUN_000224-T2 439 SAELDAVYRLYCREYELQLQLQQQQIEL-----QKQQLQLQQQLQQVEALQQKQEQQRQQDEGQFKEQPQHLKPEKKQQEQRQVRE 519 5666666666677666655554444444.....34445666666666666666666666554443222222222222222222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (847 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3378 (0.132237); expected 510.9 (0.02) Passed bias filter: 1004 (0.0393032); expected 510.9 (0.02) Passed Vit filter: 137 (0.00536308); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.53u 0.39s 00:00:00.92 Elapsed: 00:00:00.44 # Mc/sec: 7836.89 // Query: FUN_000225-T1 [L=112] Description: FUN_000225 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-06 28.5 23.9 3.2e-06 28.0 23.9 1.3 1 UPAR_LY6 u-PAR/Ly-6 domain 0.00095 20.3 29.3 0.0016 19.6 29.3 1.4 1 Toxin_TOLIP Snake toxin and toxin-like protein ------ inclusion threshold ------ 0.019 15.6 18.0 0.025 15.3 18.0 1.1 1 UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.0 23.9 3.8e-10 3.2e-06 2 81 .. 7 91 .. 6 92 .. 0.77 Alignments for each domain: == domain 1 score: 28.0 bits; conditional E-value: 3.8e-10 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig....sltvtesccqsdlCns 81 +l+Cy+C +++s+++c+s++ +Cp+g++ C++++++++g + +k+C + sc ++++ + + t +cc+s+lCns FUN_000225-T1 7 ELKCYTCSSTKSWEDCKSTQskkTCPEGQERCFKVSTEYNGT----KSYSKDCldEASCDDKDTYLQDCkaaqNSTCILTCCSSELCNS 91 79****************999******************964....5566677664444444333322234557788889********8 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 29.3 1.9e-07 0.0016 1 72 [] 8 90 .. 8 90 .. 0.77 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 1.9e-07 Toxin_TOLIP 1 LkCytCeeeksnsnCl...ketkCsesekyCvttvtsakskklisksCsss..Ceessselgvas......vsvsCCqtdlCN 72 LkCytC+++ks ++C+ ++++C+e ++ C ++ t+ + +k++sk+C ++ C ++++ l+ + ++CC+++lCN FUN_000225-T1 8 LKCYTCSSTKSWEDCKstqSKKTCPEGQERCFKVSTEYNGTKSYSKDCLDEasCDDKDTYLQDCKaaqnstCILTCCSSELCN 90 89*************94334679*************997799******876448866554443322222236679*******9 PP >> UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 18.0 2.9e-06 0.025 6 89 .. 6 90 .. 2 97 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.9e-06 UPAR_LY6_2 6 ksfkcftcekaadnyecnrwaedkycpretkycltvhklesegksvsvtkkcaaleecllvgc..reskeeehkect.sccegnicn 89 + +kc+tc ++ +c k cp+ + c+ v + e +g ++s +k c + c ++ k ++ c+ +cc ++cn FUN_000225-T1 6 HELKCYTCSSTKSWEDCKSTQSKKTCPEGQERCFKVST-EYNG-TKSYSKDCLDEASCDDKDTylQDCKAAQNSTCIlTCCSSELCN 90 679*******************************8865.4555.56779*******99765432277787777788549*******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (112 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1179 (0.0461538); expected 510.9 (0.02) Passed bias filter: 316 (0.0123703); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1118.13 // Query: FUN_000226-T1 [L=602] Description: FUN_000226 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-19 67.7 0.1 9.9e-19 67.7 0.1 3.5 3 LEDGF Lens epithelium-derived growth factor (LEDGF) 5.2e-18 65.8 0.1 5.2e-18 65.8 0.1 5.5 3 PWWP PWWP domain Domain annotation for each model (and alignments): >> LEDGF Lens epithelium-derived growth factor (LEDGF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.6 3.3 1.8 2.4e+04 66 93 .. 134 161 .. 122 188 .. 0.64 2 ? -10.5 12.3 2 2.6e+04 63 112 .. 292 341 .. 280 352 .. 0.60 3 ! 67.7 0.1 7.7e-23 9.9e-19 2 106 .. 397 483 .. 396 495 .. 0.92 Alignments for each domain: == domain 1 score: -4.6 bits; conditional E-value: 1.8 LEDGF 66 kldeeeevefkekakeirekAeeiYnkf 93 +++e++e +fk k + + k ee+ + FUN_000226-T1 134 NKSEKKEKSFKGKKQSVSGKKEEMSKAG 161 5667777888888888877777765544 PP == domain 2 score: -10.5 bits; conditional E-value: 2 LEDGF 63 eewkldeeeevefkekakeirekAeeiYnkfkslflvpegeanfwedfee 112 e++k ++++e + +ek ++i ek ++ +k k+ l++++ ++++ +e FUN_000226-T1 292 EKSKSKDDTERKKQEKLQKIAEKKAMLKEKKKKEKLEQKKAEKAKMLEKE 341 45566666677777888888888888877776666544444233322222 PP == domain 3 score: 67.7 bits; conditional E-value: 7.7e-23 LEDGF 2 rklveldaeikeaLkldkadvkkcleaLdelkklqvtklmLkknpevvetikklrrYvgnleewkldeeeevefkekakeirekAeeiYnkfkslf 97 + l +++ ++ ++L ++ +dv kcl++++++ ++++++ ++kknpe+v+tik++r+Y+ n +++rekA+++Y++fkslf FUN_000226-T1 397 EILDKMNYNLVMSLTVEAPDVPKCLKIITQISEMEINPDIIKKNPEIVQTIKRIRNYKQN------------------SKVREKASQLYTQFKSLF 474 56778999999*************************************************..................9***************** PP LEDGF 98 lvpegeanf 106 + +++++ FUN_000226-T1 475 SIAGADSSV 483 977776555 PP >> PWWP PWWP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.8 0.1 4.1e-22 5.2e-18 1 91 [. 6 86 .. 6 88 .. 0.83 2 ? -9.9 10.7 2 2.6e+04 84 84 .. 146 146 .. 109 230 .. 0.67 3 ? -20.5 24.4 2 2.6e+04 73 73 .. 331 331 .. 274 401 .. 0.67 Alignments for each domain: == domain 1 score: 65.8 bits; conditional E-value: 4.1e-22 PWWP 1 gdlvwaKlkgypwWParvvdpeelpenvlkkkkkskklylVrFfgdseyawvkekdlkpfteeeekeelkkkkkkkkkkafkkaveeaeea 91 gdl+waK++gyp+WPar+ p e +e++ kk + ++Ffg++e+a ++ kdl+p+++++ek+ +++++++ + fk+a+ e+ e+ FUN_000226-T1 6 GDLIWAKMRGYPHWPARIDLPAE-GEKIPPKK------FAIFFFGTHETAVMQAKDLFPYEKNKEKFLKNSNRSR---RGFKEALVEILEN 86 8*****************99866.45555554......**********************999966555555554...39******99886 PP == domain 2 score: -9.9 bits; conditional E-value: 2 PWWP 84 a 84 FUN_000226-T1 146 K 146 1 PP == domain 3 score: -20.5 bits; conditional E-value: 2 PWWP 73 k 73 k FUN_000226-T1 331 K 331 1 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (602 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4759 (0.186299); expected 510.9 (0.02) Passed bias filter: 892 (0.0349188); expected 510.9 (0.02) Passed Vit filter: 526 (0.0205911); expected 25.5 (0.001) Passed Fwd filter: 140 (0.00548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 1.28u 0.47s 00:00:01.75 Elapsed: 00:00:00.51 # Mc/sec: 4763.64 // Query: FUN_000228-T1 [L=227] Description: FUN_000228 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-54 182.1 0.0 9.8e-54 181.8 0.0 1.1 1 Ras Ras family 1.3e-30 106.6 0.0 2e-30 106.0 0.0 1.3 1 Roc Ras of Complex, Roc, domain of DAPkinase 1.4e-12 48.0 0.0 2.6e-12 47.1 0.0 1.4 1 Arf ADP-ribosylation factor family 1.6e-05 25.3 0.1 0.032 14.5 0.0 2.1 2 RsgA_GTPase RsgA GTPase 3.2e-05 24.1 0.0 6.3e-05 23.1 0.0 1.5 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.0076 16.2 0.1 0.019 14.9 0.1 1.7 1 Gtr1_RagA Gtr1/RagA G protein conserved region ------ inclusion threshold ------ 0.018 15.6 0.0 0.031 14.9 0.0 1.4 1 MMR_HSR1 50S ribosome-binding GTPase 0.065 13.4 0.1 0.42 10.8 0.0 1.9 2 AAA_24 AAA domain 0.071 13.2 0.6 0.69 10.0 0.1 2.3 2 DO-GTPase2 Double-GTPase 2 0.17 12.7 0.1 1.4 9.7 0.0 2.1 2 AAA_22 AAA domain 0.22 11.6 0.1 0.31 11.1 0.1 1.2 1 CNK2_3_dom Connector enhancer of kinase suppressor of ras 2 Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 181.8 0.0 4.2e-57 9.8e-54 1 161 [. 12 184 .. 12 185 .. 0.97 Alignments for each domain: == domain 1 score: 181.8 bits; conditional E-value: 4.2e-57 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevd...........gkevklqiwDTAGqerfralreayyrgaegillvyditsee 85 k++ +GdsgvGK+sll+++++++F+ +++sT+g+df +k+v + g++v+lq+wDTAGqerfr+l++a++r+a+g+llv+d+t+e+ FUN_000228-T1 12 KFLALGDSGVGKTSLLFQYTDKAFNPKFISTVGIDFREKRVIHHplnpdgsrssrGQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLVFDLTHEQ 107 7899************************************9888899999999999**************************************** PP Ras 86 sfenvkkwleeikrvae.envpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 sf n+++wl++++++a en ivl+Gnk+Dle++++v+++e+++la++lglk++etSA + +nv+e e+l+++++ FUN_000228-T1 108 SFLNIRNWLSQLQTHAYcENPDIVLIGNKADLEDQKQVDENEARTLAENLGLKYFETSALSGHNVSESVEALLDQVM 184 ***************99999***************************************************999885 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.0 0.0 8.5e-34 2e-30 1 119 [] 12 138 .. 12 138 .. 0.87 Alignments for each domain: == domain 1 score: 106.0 bits; conditional E-value: 8.5e-34 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkik....glendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...s 89 K + lGdsgvGKtsll +++++ f++k st+g+df +k++ + g +++++ ++++l++WDtaGqerfrsl++ ++r+a +++lvfd + FUN_000228-T1 12 KFLALGDSGVGKTSLLFQYTDKAFNPKFISTVGIDFREKRVIHHPlnpdG-SRSSRGQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLVFDlthE 106 6788***********************************99754321213.45567899*********************************9766 PP Roc 90 rssenlkeWlkelkev..agkspvilvgnkiD 119 +s+ n+++Wl++l+++ +++ ++l+gnk D FUN_000228-T1 107 QSFLNIRNWLSQLQTHayCENPDIVLIGNKAD 138 78889********8763377889*******98 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.1 0.0 1.1e-15 2.6e-12 15 173 .. 11 182 .. 2 183 .. 0.89 Alignments for each domain: == domain 1 score: 47.1 bits; conditional E-value: 1.1e-15 Arf 15 lrilllGLDnaGKtTilkklkleelvt.tiPTigfnveevei...............knlkftvwDvGGqeklRplWknYfektdavifvvDsadr 94 l+ l lG + GKt +l +++++ ++ i T+g + +e ++ + +++++wD Gqe+ R+l +f++ + + v D +++ FUN_000228-T1 11 LKFLALGDSGVGKTSLLFQYTDKAFNPkFISTVGIDFREKRVihhplnpdgsrssrgQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLVFDLTHE 106 688999*99*************9998548899997776544445899*******99999************************************* PP Arf 95 eRleeakeeLkalleeeelkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkeglewlses 173 + + + ++ L++l ++ ++ +++++NK Dl++ + +e ++ e+l l+ +++sa++g++++e++e l ++ FUN_000228-T1 107 QSFLNIRNWLSQLQTHAYCENPDIVLIGNKADLEDQKQVDENEARTLAENL---GLKYFETSALSGHNVSESVEALLDQ 182 **********************************99988887766555555...678899*************999886 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.00081 1.9 112 128 .. 16 32 .. 11 42 .. 0.83 2 ! 14.5 0.0 1.4e-05 0.032 47 127 .. 121 201 .. 94 220 .. 0.72 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00081 RsgA_GTPase 112 lGqSGvGKStLinallp 128 lG SGvGK++L+ + ++ FUN_000228-T1 16 LGDSGVGKTSLLFQYTD 32 7**********977665 PP == domain 2 score: 14.5 bits; conditional E-value: 1.4e-05 RsgA_GTPase 47 vlaeesgiepvivlnKiDlleeee.eleelkkeyealgyevllvsaktgegleelkellkgkttvllGqSGvGKStLinall 127 ++a ++ ++v++ nK+Dl ++++ + +e ++ +e+lg++ + +sa +g+++ e e+l ++++ + + v K tL n++l FUN_000228-T1 121 THAYCENPDIVLIGNKADLEDQKQvDENEARTLAENLGLKYFETSALSGHNVSESVEALLDQVMRRM-ENCVDKDTLPNNVL 201 44555566777778*********98888899999***************999887777777665544.34466666666555 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 3.1 7.3e+03 6 20 .. 13 27 .. 10 32 .. 0.81 2 ! 23.1 0.0 2.7e-08 6.3e-05 66 185 .. 67 182 .. 40 189 .. 0.74 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 3.1 GTP_EFTU 6 igiighvDhGKtTlt 20 + +g+ GKt+l+ FUN_000228-T1 13 FLALGDSGVGKTSLL 27 667899999***986 PP == domain 2 score: 23.1 bits; conditional E-value: 2.7e-08 GTP_EFTU 66 tkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveG.....vepqteevlrlarklgvpiivviNKmDrvdeaelkevveevkeellekvge 156 +++ +++l Dt G + F + +++ + + g +lv+d ++ + + ++ +a ++ i+++ NK D+ + k+v e+ ++l e+ FUN_000228-T1 67 GQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLVFDLTHEqsflnIRNWLSQLQTHAYCENPDIVLIGNKADLE---DQKQVDENEARTLAENL-- 157 78899*********************************995444333333333333444444599999*****9...45556666666664333.. PP GTP_EFTU 157 kgekevpvvpgSalkgegvkellealvel 185 +++ +Sal+g +v e +eal + FUN_000228-T1 158 ----GLKYFETSALSGHNVSESVEALLDQ 182 ....4567899999999888666666543 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.9 0.1 8.2e-06 0.019 36 131 .. 58 147 .. 12 166 .. 0.69 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 8.2e-06 Gtr1_RagA 36 dveksevrflgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveske.leedlarlketlealsevspeakvfvlihKvDlisedkre 130 +++ s+ + + ++l+lwd Gqe+f + f++ + vfD + ++ + + + l+++ ++++ +p++ + +K Dl ++++ + FUN_000228-T1 58 NPDGSRSSRGQRVHLQLWDTAGQERFRSLT-----TAFFRDAMGFLLVFDLTHEQsFLNIRNWLSQLQTHAYCENPDI--VLIGNKADLEDQKQVD 146 5555666667889***********997765.....889**************66535555555555555555555654..4445888887766544 PP Gtr1_RagA 131 e 131 e FUN_000228-T1 147 E 147 4 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 1.4e-05 0.031 5 112 .. 16 135 .. 12 136 .. 0.67 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 1.4e-05 MMR_HSR1 5 vGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkgkk.............ielvDtpGliegaseee.gleraflaieeadlillvvd.. 84 +G + vGK++L+ + t k + + + + d e+++ ++ + ++l+Dt+G e ++ +l+ af + +a llv+d FUN_000228-T1 16 LGDSGVGKTSLLFQYTDKAFNPKFISTVGIDFREKRVIHHPLNpdgsrssrgqrvhLQLWDTAG-QE----RFrSLTTAFFR--DAMGFLLVFDlt 104 7999************9966666666666666666665442112344467777777********.65....44488888884..899999999976 PP MMR_HSR1 85 aeeglteldeeleellee...ekkpvilvln 112 +e+++ ++++ l +l+++ e+ +++l+ n FUN_000228-T1 105 HEQSFLNIRNWLSQLQTHaycENPDIVLIGN 135 4344555655555555445545555666666 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00018 0.42 4 26 .. 12 34 .. 10 53 .. 0.83 2 ? 0.4 0.0 0.27 6.2e+02 122 172 .. 124 190 .. 105 213 .. 0.57 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00018 AAA_24 4 kvliyGpsgiGKTtlakslpkpl 26 k+l G+sg+GKT+l++++ + + FUN_000228-T1 12 KFLALGDSGVGKTSLLFQYTDKA 34 78899*************95544 PP == domain 2 score: 0.4 bits; conditional E-value: 0.27 AAA_24 122 k....nvvfiah....ekerkdedeege........kytryepklgektakeleeivDlvlrlelke 172 + ++v+i+ e++++++++e++ ky + g +++ +e ++D v+r + FUN_000228-T1 124 YcenpDIVLIGNkadlEDQKQVDENEARtlaenlglKYFETSALSGHNVSESVEALLDQVMRRMENC 190 3555567777652111233333333333666666666666666667777888888888888755554 PP >> DO-GTPase2 Double-GTPase 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.16 3.8e+02 6 20 .. 16 30 .. 15 55 .. 0.79 2 ? 10.0 0.1 0.0003 0.69 118 209 .. 92 178 .. 60 190 .. 0.74 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.16 DO-GTPase2 6 vGppdaGKTtllasl 20 +G+++ GKT+ll FUN_000228-T1 16 LGDSGVGKTSLLFQY 30 799********9765 PP == domain 2 score: 10.0 bits; conditional E-value: 0.0003 DO-GTPase2 118 rhAdailllvDgealasgekrglarddlrqllerlaeelagrpkirlavvwtKsdl...eevaerilaeikeelaeaglraaeievaevaassed 209 r A +ll+ D + ++ ++r+ l +l++++ ++++ K+dl ++v+e+ +++ e l+ + ++++ ++ ++v++s e FUN_000228-T1 92 RDAMGFLLVFDLTH-------EQSFLNIRNWLSQLQTHAYCEN-PDIVLIGNKADLedqKQVDENEARTLAENLGLKYFETSALSGHNVSESVEA 178 55555555555333.......3555678999999999998844.59**********9999999999999******99999999999999987665 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.0 0.00061 1.4 11 33 .. 16 49 .. 13 142 .. 0.67 2 ? 1.5 0.0 0.22 5e+02 27 79 .. 117 187 .. 108 201 .. 0.64 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00061 AAA_22 11 tGesGtGKTtllrrlleqldee...........d 33 G+sG+GKT ll ++++++ + + FUN_000228-T1 16 LGDSGVGKTSLLFQYTDKAFNPkfistvgidfrE 49 69**************997533455555555544 PP == domain 2 score: 1.5 bits; conditional E-value: 0.22 AAA_22 27 eqldee....ddsvv....lvelpsstspkdl.lrellralglelek.........elskeellaalqeal 79 +ql+ + ++++v + +l +++ ++ +r+l+++lgl+ + +s e+ll+++++ + FUN_000228-T1 117 SQLQTHayceNPDIVlignKADLEDQKQVDENeARTLAENLGLKYFEtsalsghnvSESVEALLDQVMRRM 187 44444466664444446667777777766666688899999988888888885555555555555555554 PP >> CNK2_3_dom Connector enhancer of kinase suppressor of ras 2/3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 0.00013 0.31 37 89 .. 162 214 .. 149 221 .. 0.83 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00013 CNK2_3_dom 37 ssrtglpgakgsESPnsfLdqesrrrftiadsdqllvgyevearvlpaklRek 89 + ++l+g++ sES + Ldq rr + +d+d+l+ + + +klRe FUN_000228-T1 162 FETSALSGHNVSESVEALLDQVMRRMENCVDKDTLPNNVLNNNPNRGTKLREV 214 455678999**************************997777777888999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (227 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 803 (0.0314347); expected 510.9 (0.02) Passed bias filter: 680 (0.0266197); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2236.07 // Query: FUN_000229-T1 [L=309] Description: FUN_000229 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-24 85.4 0.0 3.2e-22 79.3 0.0 2.3 2 Cyclin_C_2 Cyclin C-terminal domain 1.4e-10 41.5 0.2 2.5e-10 40.7 0.2 1.5 1 Cyclin_N Cyclin, N-terminal domain 5.8e-05 23.5 0.0 0.04 14.4 0.0 2.5 2 TFIIB Transcription factor TFIIB repeat 0.0035 18.2 0.1 0.098 13.5 0.1 2.3 2 Spy1 Cell cycle regulatory protein ------ inclusion threshold ------ 0.028 14.9 0.2 0.14 12.7 0.1 2.2 2 Cyclin_C Cyclin, C-terminal domain Domain annotation for each model (and alignments): >> Cyclin_C_2 Cyclin C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.018 94 24 65 .. 87 128 .. 72 161 .. 0.78 2 ! 79.3 0.0 6.2e-26 3.2e-22 1 86 [. 171 252 .. 171 285 .. 0.86 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.018 Cyclin_C_2 24 ieklykkareilksalltDayflYtPsqialaallladekla 65 +++++++a +lk+ +l ++ ++P + l +l++a + + FUN_000229-T1 87 PGAVTATAVAYLKRFYLKTSVMDHPPREMFLVCLYMACKVEE 128 567788999999999*********************998766 PP == domain 2 score: 79.3 bits; conditional E-value: 6.2e-26 Cyclin_C_2 1 hPfRpLeGflldlktrlkslekrieklykkareilksalltDayflYtPsqialaallladeklaerylteklgkkeskekaklek 86 +P+Rp+eGf++d+ktr+++l+ ++ek+++ka+e+l++allt + +lY+Psqialaal a+e+ y+++ lg+++++ l + FUN_000229-T1 171 NPYRPMEGFIIDIKTRCPKLD-DPEKWRTKAEEFLRKALLTNVLLLYSPSQIALAALFNASEGSLACYIENDLGEHNERV---LRQ 252 7*******************8.***************************************************8754433...333 PP >> Cyclin_N Cyclin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.7 0.2 4.8e-14 2.5e-10 37 126 .. 74 167 .. 40 168 .. 0.87 Alignments for each domain: == domain 1 score: 40.7 bits; conditional E-value: 4.8e-14 Cyclin_N 37 wlvevhekfk..lspetlylavnyldRflskksvpkkklqlvgvtcLllAaKyeeisppkvedlvyit..dn.aytkeeilemErliLetLkfdl 126 l+ev+ kf+ + + ++av yl Rf+ k sv + + ++++cL++A+K+ee + +v+ +v i d tke il+ E+l+++ L f+l FUN_000229-T1 74 VLMEVCDKFRppVPGAVTATAVAYLKRFYLKTSVMDHPPREMFLVCLYMACKVEEHN-ISVDRFVEILpaDRrEKTKEFILAHELLLMQRLSFHL 167 489999999866778899*************************************95.99*****99966335889999**************98 PP >> TFIIB Transcription factor TFIIB repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.0 7.7e-06 0.04 24 75 .. 89 140 .. 75 153 .. 0.85 2 ! 6.3 0.0 0.0026 13 12 59 .. 183 230 .. 180 234 .. 0.92 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 7.7e-06 TFIIB 24 kVadaAkelaklaveekllkGrspagiaaAalyiAcrleevkrtlkeissvl 75 V+ +A+ +k+ + + + p ++ +ly+Ac+ ee++ ++ +++++l FUN_000229-T1 89 AVTATAVAYLKRFYLKTSVMDHPPREMFLVCLYMACKVEEHNISVDRFVEIL 140 588888888888888888888899999999*****************99987 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0026 TFIIB 12 ikrfadaleLpekVadaAkelaklaveekllkGrspagiaaAalyiAc 59 ik + +l+ pek + +A+e++++a+ ++l sp++ia Aal+ A+ FUN_000229-T1 183 IKTRCPKLDDPEKWRTKAEEFLRKALLTNVLLLYSPSQIALAALFNAS 230 6777999999**********************************9887 PP >> Spy1 Cell cycle regulatory protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.1 1.9e-05 0.098 33 109 .. 91 169 .. 56 174 .. 0.72 2 ? 2.3 0.0 0.054 2.8e+02 30 78 .. 206 255 .. 199 279 .. 0.76 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.9e-05 Spy1 33 lamvlvYfkraglaseeyk...rinfflaLylAndmEedeeeskleifpfllgknwkeevpkfl.klrdellarmeyraav 109 a ++Y kr l+++ r f++ Ly+A+++Ee + ++++ f +l +++e++++f l++r++++ +v FUN_000229-T1 91 TATAVAYLKRFYLKTSVMDhppREMFLVCLYMACKVEEHNISVDR--FVEILPADRREKTKEFIlAHELLLMQRLSFHLTV 169 578899999999887765422278899**********99877665..4345555666666666514555667788887776 PP == domain 2 score: 2.3 bits; conditional E-value: 0.054 Spy1 30 kyLlamvlvYfkraglas.eeykrinfflaLylAndmEedeeeskleifp 78 k Ll+ vl ++ +++a + ++ ++ la y+ nd+ e +e++ ++i FUN_000229-T1 206 KALLTNVLLLYSPSQIALaALFNASEGSLACYIENDLGEHNERVLRQINL 255 5677777777777776651568999999*********9999888777654 PP >> Cyclin_C Cyclin, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 0.47 2.4e+03 48 61 .. 92 105 .. 70 132 .. 0.70 2 ? 12.7 0.1 2.7e-05 0.14 15 57 .. 192 231 .. 181 304 .. 0.84 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.47 Cyclin_C 48 Aaaavylarktlns 61 A+a+ yl r+ l++ FUN_000229-T1 92 ATAVAYLKRFYLKT 105 55555555555433 PP == domain 2 score: 12.7 bits; conditional E-value: 2.7e-05 Cyclin_C 15 daskdleletlakylleltlldydflkyppSliAaaavylark 57 d + + +t a+ +l +ll +l y+pS+iA aa++ a+ FUN_000229-T1 192 DP--E-KWRTKAEEFLRKALLTNVLLLYSPSQIALAALFNASE 231 33..4.88999***************************98876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 720 (0.0281856); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.43s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3034.98 // Query: FUN_000230-T1 [L=611] Description: FUN_000230 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-13 51.7 0.0 9e-11 42.4 0.0 3.1 2 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family Domain annotation for each model (and alignments): >> Exo_endo_phos Endonuclease/Exonuclease/phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.4 0.0 3.5e-15 9e-11 2 166 .. 140 345 .. 139 381 .. 0.76 2 ! 3.2 0.0 0.0037 93 172 224 .] 511 600 .. 493 600 .. 0.64 Alignments for each domain: == domain 1 score: 42.4 bits; conditional E-value: 3.5e-15 xxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Exo_endo_phos 2 twNvngg.............nadaardparldalaellraydpDvllLQEvdlddaealllalla.lggyysyvysggggggggGvailsrfplts 83 ++Nv+ + + + ++++r+++l++ + +y++Dv++LQEv + ea ++ l+ +g y + +++++ +G+a++++++ ++ FUN_000230-T1 140 SYNVLADgllhahselypgvEQWMKDWEYRRRNLLQEILHYKADVICLQEVEKCHFEAWFEPRLKeKG-YTGIYMK-RTRDKTDGCATFFKHSRFT 233 67777777777777777777777789************************877777777777776533.4443355.999**************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................... RF Exo_endo_phos 84 vivrtlsedgdpslrialapvggtlvvlvvl.....pappapprlarreqrlllllllaallaarsgpvil......................... 149 +++++l + p++r ++ + +v l p FUN_000230-T1 234 LVKSKLVSFLKPDVRLMDRDNVAIVVLLKPKcrtgkP---------------------------------Ppqksnnlicvsnthvlfnkkrgdik 296 ********************99998666655555653.................................04444444444444444444444444 PP ................................xxxxxxxxxxxxxxxxx RF Exo_endo_phos 150 ................................aGDfNaapdsgdlrrll 166 +GDfN++p s+ +++ + FUN_000230-T1 297 laqltclfaeinemaritspdcgdckhhpiicCGDFNSTPYSPIYNFVA 345 44444445888888888888888888888888******99888776655 PP == domain 2 score: 3.2 bits; conditional E-value: 0.0037 x.........xx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........................xxxxx RF Exo_endo_phos 172 l.........sf.....ggggtgfgttptartpnggsrlDyilvsgglavrsvgvlidpgal........................tgSDH 224 + +f + +g++ +t ++++ ++ Dy ++s+g++ + ++ g l +SDH FUN_000230-T1 511 DsctsqkhgfNFysvyrHDLQNGWPKVTTFHDSGSTTV-DYMFASRGIRKSCYKCKSQHGCLelegnlnllsegdirqlgglpnkfISSDH 600 33444434352234455667778888888888888888.*******999988877666665566666666666666666666666666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (611 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1026 (0.0401644); expected 510.9 (0.02) Passed bias filter: 461 (0.0180466); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5838.42 // Query: FUN_000231-T1 [L=1547] Description: FUN_000231 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-64 211.0 114.8 7.8e-06 26.0 0.2 17.7 17 MORN MORN repeat 5.3e-48 164.1 7.0 1.1e-47 163.0 7.0 1.5 1 RhoGEF RhoGEF domain 3.7e-05 24.0 0.0 7.5e-05 23.1 0.0 1.5 1 PH_alsin Alsin PH-like domain 0.00069 20.2 0.1 0.0032 18.1 0.0 2.1 2 RHG20_PH Rho GTPase-activating protein 20, PH domain 0.0056 17.1 0.2 0.024 15.1 0.2 2.2 1 PH_13 Pleckstrin homology domain ------ inclusion threshold ------ 0.011 16.8 0.0 0.04 14.9 0.0 2.1 1 PH PH domain 0.35 11.2 10.5 3.4 8.0 0.0 5.6 5 DUF2158 Uncharacterized small protein (DUF2158) Domain annotation for each model (and alignments): >> MORN MORN repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.1 6e-08 0.00022 1 21 [. 1130 1150 .. 1130 1152 .. 0.95 2 ! 15.6 0.5 4.4e-06 0.016 1 22 [. 1153 1174 .. 1153 1175 .. 0.97 3 ! 22.0 0.5 3.9e-08 0.00014 1 23 [] 1176 1198 .. 1176 1198 .. 0.97 4 ! 15.3 3.6 5.2e-06 0.019 1 22 [. 1199 1220 .. 1199 1221 .. 0.97 5 ! 6.2 0.0 0.0041 15 1 21 [. 1222 1242 .. 1222 1244 .. 0.94 6 ! 21.7 2.5 4.7e-08 0.00017 1 23 [] 1245 1267 .. 1245 1267 .. 0.97 7 ! 21.1 0.6 7.6e-08 0.00028 1 22 [. 1268 1289 .. 1268 1290 .. 0.97 8 ! 17.2 1.5 1.3e-06 0.0047 1 22 [. 1291 1312 .. 1291 1313 .. 0.97 9 ! 17.9 0.6 8.2e-07 0.003 1 22 [. 1314 1335 .. 1314 1336 .. 0.97 10 ! 9.8 2.9 0.0003 1.1 1 23 [] 1337 1359 .. 1337 1359 .. 0.96 11 ? 3.9 0.7 0.023 82 1 23 [] 1360 1382 .. 1360 1382 .. 0.89 12 ! 26.0 0.2 2.1e-09 7.8e-06 1 22 [. 1383 1404 .. 1383 1405 .. 0.95 13 ! 12.2 0.7 5.2e-05 0.19 1 21 [. 1406 1426 .. 1406 1428 .. 0.95 14 ! 8.5 0.5 0.0008 2.9 1 17 [. 1429 1445 .. 1429 1449 .. 0.94 15 ! 23.5 2.1 1.3e-08 4.9e-05 1 17 [. 1453 1469 .. 1453 1473 .. 0.92 16 ! 23.4 0.2 1.4e-08 5.2e-05 1 17 [. 1475 1491 .. 1475 1493 .. 0.93 17 ! 17.5 0.4 1e-06 0.0038 1 22 [. 1498 1519 .. 1498 1520 .. 0.91 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 6e-08 MORN 1 YeGewknGkrhGkGvytwpdG 21 Y+G+ + GkrhG+G++ wp+ FUN_000231-T1 1130 YCGNLVSGKRHGHGTLSWPNQ 1150 9******************96 PP == domain 2 score: 15.6 bits; conditional E-value: 4.4e-06 MORN 1 YeGewknGkrhGkGvytwpdGd 22 Y+G+w+++ r+G G + + +Gd FUN_000231-T1 1153 YQGDWRDDDRCGVGELLYNSGD 1174 *********************9 PP == domain 3 score: 22.0 bits; conditional E-value: 3.9e-08 MORN 1 YeGewknGkrhGkGvytwpdGdr 23 Y G+w ++k hG G++++ +Gd+ FUN_000231-T1 1176 YKGQWLDDKQHGTGTLHYINGDV 1198 9********************96 PP == domain 4 score: 15.3 bits; conditional E-value: 5.2e-06 MORN 1 YeGewknGkrhGkGvytwpdGd 22 Y G+w +G +hGkG+ + +Gd FUN_000231-T1 1199 YHGQWFEGDMHGKGTINFKNGD 1220 99*******************8 PP == domain 5 score: 6.2 bits; conditional E-value: 0.0041 MORN 1 YeGewknGkrhGkGvytwpdG 21 +eG++ ++ hG G +++ +G FUN_000231-T1 1222 FEGDFDHNEIHGDGELICDNG 1242 79*****************99 PP == domain 6 score: 21.7 bits; conditional E-value: 4.7e-08 MORN 1 YeGewknGkrhGkGvytwpdGdr 23 Y G w + k+hGkG++++p+Gd+ FUN_000231-T1 1245 YKGKWEQSKKHGKGWMHFPNGDV 1267 99*******************96 PP == domain 7 score: 21.1 bits; conditional E-value: 7.6e-08 MORN 1 YeGewknGkrhGkGvytwpdGd 22 Y+G++ n++++G+G ++++dG+ FUN_000231-T1 1268 YSGDFANDQCNGHGEMHYADGS 1289 9********************8 PP == domain 8 score: 17.2 bits; conditional E-value: 1.3e-06 MORN 1 YeGewknGkrhGkGvytwpdGd 22 Y G+w++++r G G ++ +dG+ FUN_000231-T1 1291 YKGQWVDNRRGGEGEFRSSDGT 1312 9********************7 PP == domain 9 score: 17.9 bits; conditional E-value: 8.2e-07 MORN 1 YeGewknGkrhGkGvytwpdGd 22 Y G w++++ +G G++ +++Gd FUN_000231-T1 1314 YTGGWSKDLINGPGRMEYSNGD 1335 9********************9 PP == domain 10 score: 9.8 bits; conditional E-value: 0.0003 MORN 1 YeGewknGkrhGkGvytwpdGdr 23 Y G+w ++ r G+Gv+++++Gd+ FUN_000231-T1 1337 YNGNWFKNTRYGQGVMKYSNGDV 1359 89*******************96 PP == domain 11 score: 3.9 bits; conditional E-value: 0.023 MORN 1 YeGewknGkrhGkGvytwpdGdr 23 Y G + ++++ +G++t+ dG++ FUN_000231-T1 1360 YNGGFEYDLCSKNGKMTYKDGSV 1382 7889999999999********85 PP == domain 12 score: 26.0 bits; conditional E-value: 2.1e-09 MORN 1 YeGewknGkrhGkGvytwpdGd 22 YeG w+nG+rhG G++ +++ + FUN_000231-T1 1383 YEGLWSNGLRHGEGKMSYANKS 1404 *******************976 PP == domain 13 score: 12.2 bits; conditional E-value: 5.2e-05 MORN 1 YeGewknGkrhGkGvytwpdG 21 YeG w +G+rh Gv+t+++ FUN_000231-T1 1406 YEGRWFYGMRHYEGVLTYANH 1426 *******************96 PP == domain 14 score: 8.5 bits; conditional E-value: 0.0008 MORN 1 YeGewknGkrhGkGvyt 17 Y G+w +k +G+G y+ FUN_000231-T1 1429 YHGQWDFDKQQGRGMYK 1445 99************996 PP == domain 15 score: 23.5 bits; conditional E-value: 1.3e-08 MORN 1 YeGewknGkrhGkGvyt 17 YeGewknG++hGkGv++ FUN_000231-T1 1453 YEGEWKNGLKHGKGVEK 1469 **************985 PP == domain 16 score: 23.4 bits; conditional E-value: 1.4e-08 MORN 1 YeGewknGkrhGkGvyt 17 YeGewk+++rhG+G+++ FUN_000231-T1 1475 YEGEWKDNMRHGQGTEV 1491 **************985 PP == domain 17 score: 17.5 bits; conditional E-value: 1e-06 MORN 1 YeGewknGkrhGkGvytwpdGd 22 YeG wk++k+hG G+ + +G FUN_000231-T1 1498 YEGRWKENKKHGVGTKKLKSGM 1519 ***************9988885 PP >> RhoGEF RhoGEF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 163.0 7.0 3e-51 1.1e-47 1 180 [] 795 976 .. 795 976 .. 0.93 Alignments for each domain: == domain 1 score: 163.0 bits; conditional E-value: 3e-51 RhoGEF 1 vikElletEksYvkdLkilvevflkplseeellseeeiktiFsnieeilelhkkllleeLeerlekesseeqkigdvflklaekfkv......Yse 90 v+ El++tE+sYv+ L++++e f kp +e+++l ++e+ t+F+nie+++ ++k+ll L er+ ++++++q++gd+fl+ + fk+ Y++ FUN_000231-T1 795 VALELYTTERSYVRRLETVLELFKKPCEENNYLDKKELVTMFMNIEDVYAVNKDLL-FMLLERI-SHWNDQQCVGDLFLDQS--FKIidrmkiYTK 886 678*************************999*********************5555.5588899.89***********9876..444445666*** PP RhoGEF 91 Ycsnypkalkllkklkkknkkfkefleelekkpec.kgldLeslLikPvqRiprYplLLkellkhtpedhpdyenlkkaleaikevakqin 180 Yc+nyp a+kl+k++ k+k+f++f++++ +++ c gl+L+ +Li vqRiprY lLL++llk+tpe+hpdy nl+ka+++++++a +in FUN_000231-T1 887 YCNNYPAAEKLYKDKI-KKKEFEAFIHSCYEHQVCqAGLNLPAYLISVVQRIPRYLLLLQDLLKRTPENHPDYANLSKAFAKMENLAVYIN 976 **************66.******************779*************************************************9998 PP >> PH_alsin Alsin PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 2.1e-08 7.5e-05 57 108 .. 1045 1104 .. 992 1106 .. 0.74 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 2.1e-08 PH_alsin 57 vtyPLstlWv........ksegelelrittPEksfllvtrtseakkvWldqlqssikaaL 108 +t L tlW +s +e +l+i tPE+s+ + + t+++kkvWl++l++++ +aL FUN_000231-T1 1045 KTLDLATLWCmdlggdnpQSAKEDSLEIYTPEHSYIMYAGTKNEKKVWLQKLRTAVAQAL 1104 555666666521111111344566677*******************************99 PP >> RHG20_PH Rho GTPase-activating protein 20, PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.2 4.5e+03 10 27 .. 931 948 .. 926 956 .. 0.86 2 ! 18.1 0.0 8.7e-07 0.0032 14 93 .] 1017 1094 .. 1006 1094 .. 0.84 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.2 RHG20_PH 10 teglktqerhlfLfsdvL 27 + +++ r+l+L +d+L FUN_000231-T1 931 ISVVQRIPRYLLLLQDLL 948 56688999********98 PP == domain 2 score: 18.1 bits; conditional E-value: 8.7e-07 RHG20_PH 14 ktqerhlfLfsdvLviaklkskksfklkkrvrlselwvascveeveeektsaeksfvlgWpttnvvatFsssevkekWls 93 +++ r L +d+Lv+a + ++s ++k+++l +lw ++ + + ++ +e+s+ + p + +++ ++++k+ Wl+ FUN_000231-T1 1017 TKKIRQAWLLNDMLVFAAKGVSRSSEVEKTLDLATLWCMDLGGD--NPQSAKEDSLEIYTPEHSYIMYAGTKNEKKVWLQ 1094 46779999*****************************7665444..34556789************************86 PP >> PH_13 Pleckstrin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.2 6.5e-06 0.024 93 149 .. 1062 1118 .. 999 1123 .. 0.86 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 6.5e-06 PH_13 93 dvsseeptfqishidrvytlkaesinertaWvkkikeaaekyietekkkrekayrar 149 +s++e++++i ++ y++ a ++ne++ W++k++ a + + e+ + + ++r FUN_000231-T1 1062 PQSAKEDSLEIYTPEHSYIMYAGTKNEKKVWLQKLRTAVAQALHGEEANESYEIESR 1118 345899********************************9999988877665554555 PP >> PH PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 1.1e-05 0.04 16 104 .. 1015 1100 .. 999 1101 .. 0.86 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 1.1e-05 PH 16 kswkk.ryfvLkdgsllyykdkkskkskepkgsislkgcevvevva.sdkekrkfvFelrtsertgdrtlllqaeseeerkeWikaiqsai 104 ++ kk r ++L ++ l++ + ++s+e ++++l ++ +++ + ++++ ++ + e+ t+ +++++++a ++ e+k W++ ++ a+ FUN_000231-T1 1015 NGTKKiRQAWLLNDMLVFAAKG-VSRSSEVEKTLDLATLWCMDLGGdNPQSAKEDSLEIYTP----EHSYIMYAGTKNEKKVWLQKLRTAV 1100 4566669*****8888888888.999*****************999777**********999....79*******************9876 PP >> DUF2158 Uncharacterized small protein (DUF2158) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.0 0.00093 3.4 20 41 .. 1165 1186 .. 1162 1192 .. 0.87 2 ? 3.5 0.1 0.024 89 20 41 .. 1188 1209 .. 1185 1218 .. 0.79 3 ? -2.5 0.1 1.8 6.4e+03 19 41 .. 1233 1255 .. 1230 1263 .. 0.83 4 ? 1.2 0.1 0.13 4.6e+02 19 41 .. 1279 1301 .. 1276 1309 .. 0.81 5 ? 0.3 0.1 0.24 8.7e+02 19 40 .. 1325 1346 .. 1315 1353 .. 0.79 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00093 DUF2158 20 aGevaaktGesyvcqWfdgkge 41 Ge+ ++G++y+ qW+d+k++ FUN_000231-T1 1165 VGELLYNSGDKYKGQWLDDKQH 1186 5889999************998 PP == domain 2 score: 3.5 bits; conditional E-value: 0.024 DUF2158 20 aGevaaktGesyvcqWfdgkge 41 +G + G+ y qWf+g+ + FUN_000231-T1 1188 TGTLHYINGDVYHGQWFEGDMH 1209 566667789**********987 PP == domain 3 score: -2.5 bits; conditional E-value: 1.8 DUF2158 19 faGevaaktGesyvcqWfdgkge 41 + Ge++ + G y+ +W + k++ FUN_000231-T1 1233 GDGELICDNGLIYKGKWEQSKKH 1255 678999999********888887 PP == domain 4 score: 1.2 bits; conditional E-value: 0.13 DUF2158 19 faGevaaktGesyvcqWfdgkge 41 + Ge+ G y+ qW d+ FUN_000231-T1 1279 GHGEMHYADGSFYKGQWVDNRRG 1301 568888999**********9765 PP == domain 5 score: 0.3 bits; conditional E-value: 0.24 DUF2158 19 faGevaaktGesyvcqWfdgkg 40 + G + G+ y +Wf++ FUN_000231-T1 1325 GPGRMEYSNGDCYNGNWFKNTR 1346 556677789**********976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1547 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 871 (0.0340967); expected 510.9 (0.02) Passed bias filter: 511 (0.0200039); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.47u 0.40s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 14672.18 // Query: FUN_000232-T1 [L=439] Description: FUN_000232 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-62 211.3 0.0 3.7e-62 211.0 0.0 1.1 1 Amidohydro_1 Amidohydrolase family 5.9e-13 49.6 0.0 3.2e-09 37.3 0.0 2.1 2 Amidohydro_3 Amidohydrolase family Domain annotation for each model (and alignments): >> Amidohydro_1 Amidohydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 211.0 0.0 2.9e-66 3.7e-62 1 345 [] 66 435 .. 66 435 .. 0.93 Alignments for each domain: == domain 1 score: 211.0 bits; conditional E-value: 2.9e-66 Amidohydro_1 1 ivlPGlIDaHvHleqsllrge...lpleewl...........vppetaaealasgiktmlksGtttvldmgattstgiealleaaeelplglrlvg 82 +++PG++D+H+H++q++++g+ pl +wl + ++a++a++++++++lk+Gttt+ ++ + ++ + l + + el g+r ++ FUN_000232-T1 66 FLIPGFVDTHIHAPQYVFTGTgydVPLLQWLekytfpveskfKCTKYAEHAYKKVVARLLKNGTTTASYFASIHLEATNVLCDVVAEL--GQRGYI 159 689***************************************9*****************************9999999999999997..****** PP Amidohydro_1 83 psvsldrt.....dgeaetrkaereklkagaaevikikadgvvkvalapheaptfsdeelkaaleeakkrglpvaiHaletkgevedaeaafggti 173 ++vs+d++ ++++ +++ +e++++ + ++ ++ ++++ ++p++ ++++ +lk++ ++a+k+++p++ H+ etk+e++++++ f FUN_000232-T1 160 GKVSMDQNspdyyVETTQKAIEDAERFVKHV----LELKNALITPVVTPRFVLSCTAHLLKQLGDVAMKYDVPIQSHLNETKNEIQMVKKSFS--- 248 **********655444555555555555555....667889999*************************************************... PP Amidohydro_1 174 ehgthlevaeslgllddiklilahgvhlsptelellaehlkgagvahcpfsnsklrsgrealrkaleeGvkvglgtDgaasgnslnlleelrlalk 269 + t++ v+++ ll++ k+ +ah++h s++el l+ ++ g+gvahcp+sn ++rsg++++r +l++ +kvglgtD ++ g s ++l +r+++k FUN_000232-T1 249 -DDTYTAVYDKHNLLNS-KTYMAHCCHSSEEELCLMVKK--GSGVAHCPTSNFNIRSGIADVRAMLDKKIKVGLGTD-VSGGESTSILVAIRDCIK 339 .669*************.*************9***99**..************************************.****************** PP Amidohydro_1 270 lqr.lla...deegglspkealrmaTingAkalglddkvGsievGkdADlvvvdl...dp.............laafvglkkdgnvkkvivkGklv 345 ++ l +e l +ea+ +aT++g ++lgld k+G +evGkd+D ++d ++ + +f l +d+n+ kv+v+G++v FUN_000232-T1 340 ASNvLSLrkpEEYKPLNFEEAFFLATLGGSQVLGLDGKIGNFEVGKDFDALLIDVeaqNSafdcfdrdntmdvIQKFLMLGDDRNILKVFVAGRVV 435 ***76669*988888****************************************875227777888889999********************997 PP >> Amidohydro_3 Amidohydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.1 3.2e-05 0.41 9 21 .. 66 78 .. 56 102 .. 0.66 2 ! 37.3 0.0 2.5e-13 3.2e-09 264 471 .. 215 435 .. 108 436 .. 0.82 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 3.2e-05 Amidohydro_3 9 lvlPGFvDsHtHl 21 +++PGFvD H+H FUN_000232-T1 66 FLIPGFVDTHIHA 78 69**********4 PP == domain 2 score: 37.3 bits; conditional E-value: 2.5e-13 Amidohydro_3 264 laelvaaarergldvaihaigdaaidrvldafeaaaeklgledrr.......riehaegltesqiervaalggaagvqpvfnfddelldsrlgker 352 l++l + a ++++++ h +++ + ++++ + +++d++ ++h++ +e+++ + + g + +p +nf + FUN_000232-T1 215 LKQLGDVAMKYDVPIQSHLNETKNEIQMVKKSFSDDTYTAVYDKHnllnsktYMAHCCHSSEEELCLMVKKGSGVAHCPTSNF-----------NI 299 6667777889999999999999998866665555533344444334444458*******************************...........99 PP Amidohydro_3 353 argstpvkellkagvkvalgsD.apvgpfdpwprigaavmrktrrggevlgpdeelsleealalyTrgpAkalgledrkGtlevGkdADlvvld.. 445 ++g+ v+++l++ +kv+lg+D + ++++ ++ i +++ ++ ++ + + + l +eea+ l T g+ ++lgl+ + G+ evGkd D ++d FUN_000232-T1 300 RSGIADVRAMLDKKIKVGLGTDvSGGESTSILVAIRDCIKASNVLSLRKPEEYKPLNFEEAFFLATLGGSQVLGLDGKIGNFEVGKDFDALLIDve 395 **********************999999999********666665547777778899*************************************99 PP Amidohydro_3 446 .....rdpltvdppeiaeer..........vrltvvdGrvv 471 d +++d + ++ + + ++ v+Grvv FUN_000232-T1 396 aqnsaFDCFDRDNTMDVI-QkflmlgddrnILKVFVAGRVV 435 998777777777664333.3699999999999999999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (439 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 770 (0.0301429); expected 510.9 (0.02) Passed bias filter: 607 (0.023762); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.35s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 4197.26 // Query: FUN_000233-T1 [L=131] Description: FUN_000233 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 11.3 20.2 1.1 10.3 20.2 1.5 1 UPAR_LY6 u-PAR/Ly-6 domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 20.2 4.2e-05 1.1 3 81 .. 20 110 .. 19 111 .. 0.80 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 4.2e-05 UPAR_LY6 3 lrCysClgessssccssgs...sC.pkgd..tqCvtttiklsgggkksslsvkgC..spscpelnetseig....sltvtesccqsdlCns 81 ++C+ C++ +s ++c s + C + g+ ++C++tt+ ++g+ ++ + k+C ++ c+e +et + +cc++d Cn+ FUN_000233-T1 20 IKCNVCYSSQSMKECISNEdlvDCdQLGAgfEVCLKTTFVYGGSDVEIKKFAKSCsyKSTCEEGSETFKRCkrvsGKICKLDCCDTDGCNN 110 79*********999999999****55544889***********99999999****998888777766655545534455778888888885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1430 (0.0559796); expected 510.9 (0.02) Passed bias filter: 505 (0.019769); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1327.63 // Query: FUN_000234-T1 [L=258] Description: FUN_000234 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.037 14.6 0.1 0.069 13.8 0.1 1.4 1 DUF2673 Protein of unknown function (DUF2673) Domain annotation for each model (and alignments): >> DUF2673 Protein of unknown function (DUF2673) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.1 2.7e-06 0.069 4 60 .. 45 101 .. 41 114 .. 0.88 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 2.7e-06 DUF2673 4 llkilliiafanpvfassmqmpdpasvtttqihamstnaqqdwiasltanqynmlsp 60 ++++ l+ + vf mq+ p vt+ + a ++i slt y+ +s FUN_000234-T1 45 VMRVSLVTDVSSSVFVCIMQLVVPLQVTAPVLQASKESIVHEYIVSLTESIYEGVSL 101 5788999999***************************************99987775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (258 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 744 (0.0291251); expected 510.9 (0.02) Passed bias filter: 566 (0.022157); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2570.46 // Query: FUN_000235-T1 [L=200] Description: FUN_000235 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.095 12.9 0.0 13 6.0 0.1 2.5 2 zf-C2H2_AcuF Oxidoreductase acuF-like, C2H2 type zinc-finger Domain annotation for each model (and alignments): >> zf-C2H2_AcuF Oxidoreductase acuF-like, C2H2 type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.1 0.00051 13 15 24 .. 27 36 .. 22 40 .. 0.83 2 ? 4.3 0.0 0.0018 45 15 26 .. 79 90 .. 73 91 .. 0.87 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.00051 zf-C2H2_AcuF 15 iksrkaWkkH 24 +s+ +WkkH FUN_000235-T1 27 LNSPNDWKKH 36 5799****** PP == domain 2 score: 4.3 bits; conditional E-value: 0.0018 zf-C2H2_AcuF 15 iksrkaWkkHVf 26 +++r Wk H f FUN_000235-T1 79 MSDRDNWKSHPF 90 67899*****99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (200 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 464 (0.018164); expected 510.9 (0.02) Passed bias filter: 444 (0.0173811); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2031.94 // Query: FUN_000236-T1 [L=760] Description: FUN_000236 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-32 110.9 213.6 0.00054 20.5 20.7 12.6 12 EGF_laminin Laminin EGF domain 1.3e-07 32.3 264.7 0.0027 18.5 11.4 19.4 17 EGF_2 EGF-like domain 2.4e-07 31.1 218.2 0.038 14.1 15.9 9.2 5 EGF_TEN Teneurin EGF domain 7.9e-07 29.5 38.9 8.9e-05 23.0 11.7 18.2 17 EGF_Teneurin Teneurin-like EGF domain 0.0005 20.8 244.2 0.0014 19.3 15.9 11.9 11 DSL Delta serrate ligand 0.0017 18.8 24.9 0.0052 17.3 6.1 12.3 11 EGF_PEAR1L Platelet endothelial aggregation receptor 1-lik ------ inclusion threshold ------ 0.026 15.5 3.3 0.026 15.5 3.3 19.4 20 hEGF Human growth factor-like EGF 0.035 15.0 0.1 0.061 14.2 0.1 1.3 1 SCIMP SCIMP protein 0.041 14.3 0.0 0.064 13.7 0.0 1.3 1 RIFIN Rifin 0.053 14.1 1.0 0.053 14.1 1.0 17.3 20 EGF_DL_JAG Delta-like/Jagged, EGF-like domain Domain annotation for each model (and alignments): >> EGF_laminin Laminin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 4.1 2.3 5.8e+03 22 34 .. 12 25 .. 6 31 .. 0.53 2 ? 1.0 20.3 0.27 6.9e+02 1 49 [] 25 69 .. 21 69 .. 0.83 3 ! 19.2 23.2 5.4e-07 0.0014 1 49 [] 67 110 .. 62 112 .. 0.86 4 ! 11.9 23.5 0.0001 0.26 1 49 [] 110 155 .. 105 155 .. 0.88 5 ? 5.3 19.1 0.012 32 1 49 [] 153 196 .. 149 198 .. 0.88 6 ! 16.6 16.6 3.6e-06 0.0093 1 49 [] 196 245 .. 196 245 .. 0.89 7 ? 5.0 13.9 0.015 39 1 47 [. 243 285 .. 242 287 .. 0.84 8 ! 19.4 12.3 4.7e-07 0.0012 1 40 [. 285 321 .. 285 327 .. 0.93 9 ! 17.0 10.6 2.6e-06 0.0067 1 49 [] 328 371 .. 328 371 .. 0.88 10 ! 20.5 20.7 2.1e-07 0.00054 1 49 [] 371 418 .. 367 418 .. 0.87 11 ! 13.0 17.8 4.7e-05 0.12 1 47 [. 416 462 .. 416 464 .. 0.87 12 ! 13.4 5.0 3.5e-05 0.09 1 33 [. 462 490 .. 461 493 .. 0.93 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 2.3 EGF_laminin 22 CkenveGrrCd.rC 34 C+++ G C +C FUN_000236-T1 12 CQPGSYGYLCSdEC 25 66666666663233 PP == domain 2 score: 1.0 bits; conditional E-value: 0.27 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr.CkpgyyglpsdspegC 49 C C++ ++C +++g C C +++G C++ C +g gl+ +++++C FUN_000236-T1 25 CRCKN-----GTCSPVDGSCYCSVGFTGAYCNKpCVNGSAGLNCTKHCNC 69 44433.....67*******************977*****99977777666 PP == domain 3 score: 19.2 bits; conditional E-value: 5.4e-07 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCd.rCkpgyyglpsdspegC 49 C+C+ g +C++ tg+C+C++++ G++C+ +Ck+g++g ++ + +C FUN_000236-T1 67 CNCSAYG----TCNQFTGTCQCQPGYGGKHCEmKCKEGFFGP-QC-RGKC 110 8888888....********************967******96.33.3355 PP == domain 4 score: 11.9 bits; conditional E-value: 0.0001 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr.CkpgyyglpsdspegC 49 C C++++ +Cd+++g+C+C+++ +G +Cd+ C + yyg++ +s+++C FUN_000236-T1 110 CLCQSNA----TCDEKDGTCDCQPGWTGVQCDNpCPSDYYGKNCNSKCKC 155 6677766....********************977*******977887777 PP == domain 5 score: 5.3 bits; conditional E-value: 0.012 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCd.rCkpgyyglpsdspegC 49 C+C++ g +C+s++g+C C ++ +G+ Cd C +ygl + +++C FUN_000236-T1 153 CKCQNGG----SCESVDGNCTCVDEWQGEICDlMCDAWTYGL--NCRNSC 196 8999888....*********************66******99..555556 PP == domain 6 score: 16.6 bits; conditional E-value: 3.6e-06 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr...CkpgyyglpsdspegC 49 C C++++ +++C+ +g+C Ck +++G Cd+ C+ g+yg++ +++++C FUN_000236-T1 196 CLCKQNQ--TERCHTISGKCFCKSGFTGLLCDQqisCTAGFYGNQCSKTCNC 245 8999999..89*********************8888*******966666565 PP == domain 7 score: 5.0 bits; conditional E-value: 0.015 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrC.drCkpgyyglpsdspe 47 C+Cn++ Cd +tg+C+C + + + C + C g yg++ ++ + FUN_000236-T1 243 CNCNGAP-----CDVVTGACDCPAGKMLPICaESCPLGSYGKKCQESC 285 8888877.....*******************778*******9555554 PP == domain 8 score: 19.4 bits; conditional E-value: 4.7e-07 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr.Ckpgyyg 40 C+C+++g +Cd++tg+C+C ++ +Gr Cd+ C++g yg FUN_000236-T1 285 CTCQNSG----SCDPVTGACSCTDGWQGRLCDKgCSEGWYG 321 99**999....*********************87**99997 PP == domain 9 score: 17.0 bits; conditional E-value: 2.6e-06 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr.CkpgyyglpsdspegC 49 C+C+++g +C +tgqC C + G+ C++ C +g +g ++C FUN_000236-T1 328 CDCSNRG----SCYHVTGQCACSAGWVGPICNKfCPEGKFGP--GCSKQC 371 *******....********************977***99986..444466 PP == domain 10 score: 20.5 bits; conditional E-value: 2.1e-07 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCd.rCkpgyyglpsdspegC 49 C+C + +++Cd +tgqC+C e+ G++Cd rC gyyg + +++++C FUN_000236-T1 371 CQCRRDS--TENCDHVTGQCSCLEGWIGDKCDkRCVAGYYGYKCQKTCQC 418 7777666..99********************967********76666666 PP == domain 11 score: 13.0 bits; conditional E-value: 4.7e-05 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr.Ckpgyyglpsdspe 47 C+Cn ++eCd ++gqC C+++++ C++ C+ g+yg++ ++++ FUN_000236-T1 416 CQCNLPR-MDAECDHRNGQCYCEPGYANIYCNEtCAAGTYGFNCSNKC 462 ****998.88*********************755********555554 PP == domain 12 score: 13.4 bits; conditional E-value: 3.5e-05 EGF_laminin 1 CeCnphgslsseCdsetgqClCkenveGrrCdr 33 C C++++ +Cd++ g C+C ++++G C++ FUN_000236-T1 462 CPCQNNS----TCDPVFGFCNCLKGFQGIYCEE 490 8888888....********************96 PP >> EGF_2 EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 16.2 0.015 38 1 32 [] 25 50 .. 12 50 .. 0.84 2 ! 17.0 19.2 3.1e-06 0.0079 7 32 .] 68 93 .. 56 93 .. 0.92 3 ? 4.6 0.8 0.023 59 22 32 .] 96 106 .. 96 106 .. 0.96 4 ! 13.7 12.4 3.5e-05 0.089 7 32 .] 111 136 .. 107 136 .. 0.94 5 ? 1.2 1.1 0.27 7e+02 23 32 .] 140 149 .. 139 149 .. 0.97 6 ! 11.5 13.5 0.00016 0.41 1 32 [] 153 179 .. 150 179 .. 0.93 7 ! 7.1 10.9 0.0038 9.6 1 32 [] 192 224 .. 192 224 .. 0.83 8 ? 1.0 3.6 0.31 7.9e+02 14 32 .] 224 239 .. 224 239 .. 0.82 9 ? -5.7 13.6 10 2.6e+04 5 26 .. 236 262 .. 230 264 .. 0.59 10 ? -0.8 0.1 1.1 2.9e+03 22 32 .] 271 281 .. 271 281 .. 0.91 11 ! 17.2 14.5 2.7e-06 0.0069 1 32 [] 281 311 .. 281 311 .. 0.91 12 ? 0.7 2.8 0.4 1e+03 23 32 .] 315 324 .. 314 324 .. 0.96 13 ! 18.5 11.4 1e-06 0.0027 7 32 .] 329 354 .. 325 354 .. 0.92 14 ? -1.9 3.9 2.6 6.6e+03 14 23 .. 367 375 .. 357 379 .. 0.66 15 ? 5.6 14.3 0.011 29 11 32 .] 378 399 .. 367 399 .. 0.85 16 ? 0.6 17.9 0.43 1.1e+03 13 32 .] 426 445 .. 403 445 .. 0.91 17 ! 6.9 10.9 0.0045 11 1 32 [] 462 488 .. 449 488 .. 0.86 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.015 EGF_2 1 CsasgliCsgrGtCvnqcGkCkCdsgyqGatC 32 C+ C+ +GtC+ G C+C+ g++Ga+C FUN_000236-T1 25 CR-----CK-NGTCSPVDGSCYCSVGFTGAYC 50 33.....76.6***87789************* PP == domain 2 score: 17.0 bits; conditional E-value: 3.1e-06 EGF_2 7 iCsgrGtCvnqcGkCkCdsgyqGatC 32 +Cs GtC++++G+C+C++gy G++C FUN_000236-T1 68 NCSAYGTCNQFTGTCQCQPGYGGKHC 93 4************************* PP == domain 3 score: 4.6 bits; conditional E-value: 0.023 EGF_2 22 kCdsgyqGatC 32 kC+ g++G++C FUN_000236-T1 96 KCKEGFFGPQC 106 6********** PP == domain 4 score: 13.7 bits; conditional E-value: 3.5e-05 EGF_2 7 iCsgrGtCvnqcGkCkCdsgyqGatC 32 C+ + tC+ + G+C+C++g++G +C FUN_000236-T1 111 LCQSNATCDEKDGTCDCQPGWTGVQC 136 599999******************** PP == domain 5 score: 1.2 bits; conditional E-value: 0.27 EGF_2 23 CdsgyqGatC 32 C+s y+G++C FUN_000236-T1 140 CPSDYYGKNC 149 ********** PP == domain 6 score: 11.5 bits; conditional E-value: 0.00016 EGF_2 1 CsasgliCsgrGtCvnqcGkCkCdsgyqGatC 32 C+ C+++G+C++ G+C C + +qG C FUN_000236-T1 153 CK-----CQNGGSCESVDGNCTCVDEWQGEIC 179 66.....********99************877 PP == domain 7 score: 7.1 bits; conditional E-value: 0.0038 EGF_2 1 CsasgliCsg.rGtCvnqcGkCkCdsgyqGatC 32 C++s+l ++ ++C + GkC C+sg++G C FUN_000236-T1 192 CRNSCLCKQNqTERCHTISGKCFCKSGFTGLLC 224 8887655555689**9888***********999 PP == domain 8 score: 1.0 bits; conditional E-value: 0.31 EGF_2 14 CvnqcGkCkCdsgyqGatC 32 C++q +C +g++G++C FUN_000236-T1 224 CDQQI---SCTAGFYGNQC 239 55555...7********** PP == domain 9 score: -5.7 bits; conditional E-value: 10 EGF_2 5 gliCsgrGtCvnqcG.........kCkCdsg 26 g++Cs tC+ c+ C+C++g FUN_000236-T1 236 GNQCSK--TCN--CNgapcdvvtgACDCPAG 262 556665..555..533555555448***987 PP == domain 10 score: -0.8 bits; conditional E-value: 1.1 EGF_2 22 kCdsgyqGatC 32 +C+ g +G++C FUN_000236-T1 271 SCPLGSYGKKC 281 5999******* PP == domain 11 score: 17.2 bits; conditional E-value: 2.7e-06 EGF_2 1 CsasgliCsgrGtCvnqcGkCkCdsgyqGatC 32 C+ s+ +C++ G+C+ +G C+C +g+qG C FUN_000236-T1 281 CQESC-TCQNSGSCDPVTGACSCTDGWQGRLC 311 77764.7*******9999*************9 PP == domain 12 score: 0.7 bits; conditional E-value: 0.4 EGF_2 23 CdsgyqGatC 32 C+ g++G+ C FUN_000236-T1 315 CSEGWYGPGC 324 ********99 PP == domain 13 score: 18.5 bits; conditional E-value: 1e-06 EGF_2 7 iCsgrGtCvnqcGkCkCdsgyqGatC 32 +Cs+rG+C + +G+C C++g+ G+ C FUN_000236-T1 329 DCSNRGSCYHVTGQCACSAGWVGPIC 354 4*******999************988 PP == domain 14 score: -1.9 bits; conditional E-value: 2.6 EGF_2 14 CvnqcGkCkC 23 C++qc +C FUN_000236-T1 367 CSKQC-QCRR 375 66445.4444 PP == domain 15 score: 5.6 bits; conditional E-value: 0.011 EGF_2 11 rGtCvnqcGkCkCdsgyqGatC 32 ++C++ +G+C+C g+ G++C FUN_000236-T1 378 TENCDHVTGQCSCLEGWIGDKC 399 579******************* PP == domain 16 score: 0.6 bits; conditional E-value: 0.43 EGF_2 13 tCvnqcGkCkCdsgyqGatC 32 C++ +G+C+C++gy +C FUN_000236-T1 426 ECDHRNGQCYCEPGYANIYC 445 6***************9999 PP == domain 17 score: 6.9 bits; conditional E-value: 0.0045 EGF_2 1 CsasgliCsgrGtCvnqc.GkCkCdsgyqGatC 32 C C+++ tC+ G C C +g+qG +C FUN_000236-T1 462 C-----PCQNNSTCDP-VfGFCNCLKGFQGIYC 488 4.....5*******83.359************* PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.2 59.1 0.0039 9.8 15 220 .. 11 137 .. 4 143 .. 0.40 2 ! 8.4 37.7 0.00082 2.1 148 221 .. 97 181 .. 96 184 .. 0.64 3 ? 2.7 72.8 0.043 1.1e+02 16 189 .. 140 312 .. 140 314 .. 0.34 4 ! 14.1 15.9 1.5e-05 0.038 179 225 .. 315 359 .. 313 362 .. 0.83 5 ! 7.2 49.5 0.0019 4.9 47 192 .. 358 492 .. 358 507 .. 0.69 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0039 EGF_TEN 15 eCkkgfeGeDCskavcpvlCs.grGayekgkCeCeegykGeeCevkv.......keceaancsgrGecie..gkCvCkpgykGkkCeektcldanC 100 C++g G Cs + c C+ g + ++g+C+C+ g++G+ C+ ++ +++++ ncs G+c + g+C+C+pgy Gk+Ce FUN_000236-T1 11 VCQPGSYGYLCSDE-CR--CKnGTCSPVDGSCYCSVGFTGAYCNKPCvngsaglNCTKHCNCSAYGTCNQftGTCQCQPGYGGKHCEM-------- 95 24444444444432.22..220222233555555555555555443211111112233444555555543334455555555555544........ PP EGF_TEN 101 sgngvCvngkCvCeegytgedCelekkackekcskkgklvkesgscvcdegytgedceeetcsldCgehgkCveskCkCdegwtGekCekktCesr 196 kC+eg+ G +C+ k C FUN_000236-T1 96 -----------------------------------------------------------------------------KCKEGFFGPQCRGK-CL-- 111 .............................................................................45555555555432.33.. PP EGF_TEN 197 CkehGvc..knGtCiCekGfngeecs 220 C+++ +c k+GtC C++G++g +c+ FUN_000236-T1 112 CQSNATCdeKDGTCDCQPGWTGVQCD 137 33333331133555555555555553 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00082 EGF_TEN 148 cdegytgedceeetcsldCgehgkCve..skCkCdegwtGekCekk........tCesrCk..ehGvck..nGtCiCekGfngeecsl 221 c+eg+ g +c + c C+++++C e ++C C+ gwtG +C++ +C+s+Ck + G c+ +G+C+C + ++ge c+l FUN_000236-T1 97 CKEGFFGPQCRGK-CL--CQSNATCDEkdGTCDCQPGWTGVQCDNPcpsdyygkNCNSKCKcqNGGSCEsvDGNCTCVDEWQGEICDL 181 7778888888764.65..7788888763357888888888888753333333337877654326677752258888888888888865 PP == domain 3 score: 2.7 bits; conditional E-value: 0.043 EGF_TEN 16 CkkgfeGeDCskavcpvlCsgrGaye..kgkCeCeegykGeeCevkvkecea.anc..........sgrGeciegkCvCkpgykGkkCeektclda 98 C + + G++C + +c+ C++ G++e +g+C+C ++++Ge C+++++ + nc ++r + i+gkC Ck+g++G C+++ +a FUN_000236-T1 140 CPSDYYGKNCNS-KCK--CQNGGSCEsvDGNCTCVDEWQGEICDLMCDAWTYgLNCrnsclckqnqTERCHTISGKCFCKSGFTGLLCDQQISCTA 232 455566666643.343..555555543356666666666666665544211101110000111100122222334444444444444444322211 PP EGF_TEN 99 nCsgngvCvngkCvCeegytgedCelekkackekcskkgklvkesgscvcdegytgedceeetcsldCgehgkCve..skCkCdegwtGekCe 189 g+ + +C C+ g+ C++ + ac+ c ++l + c g +g++c+e+ c+ C++ g+C + C+C +gw+G+ C+ FUN_000236-T1 233 --GFYGNQCSKTCNCN----GAPCDVVTGACD--CPAGKMLPICA--ESCPLGSYGKKCQES-CT--CQNSGSCDPvtGACSCTDGWQGRLCD 312 ..11222222233332....444444333332..22111111111..123344444444442.33..55555553211455555555555554 PP == domain 4 score: 14.1 bits; conditional E-value: 1.5e-05 EGF_TEN 179 CdegwtGekCekktCesrCkehGvckn..GtCiCekGfngeecsleaCp 225 C+egw G C+ ++C+ C+++G c G+C+C++G+ g c + Cp FUN_000236-T1 315 CSEGWYGPGCN-RSCD--CSNRGSCYHvtGQCACSAGWVGPIC-NKFCP 359 99999999997.5787..9999999755599999999999999.46676 PP == domain 5 score: 7.2 bits; conditional E-value: 0.0019 EGF_TEN 47 CeegykGeeCevkvkeceaancsgrGeciegkCvCkpgykGkkCeektcldanCsgngvCvngkCvCeegytgedCelekkackekcskkgklvke 142 C eg G C+ ++c +++++ + ++g+C+C +g+ G+kC+++ c+ g+ + +C+C+ + ++C++++ +c ++ + + FUN_000236-T1 358 CPEGKFGPGCSK-QCQCRR-DSTENCDHVTGQCSCLEGWIGDKCDKR-CVA---GYYGYKCQKTCQCNLPRMDAECDHRNGQCY----CEPGYANI 443 566667788874.455665.567777777888888888888888876.764...355666677888888888888888655553....33333333 PP EGF_TEN 143 sgscvcdegytgedceeetcsldCgehgkCve..skCkCdegwtGekCekkt 192 + +c +g +g +c+++ c+ C+++++C + C+C +g++G Ce+ + FUN_000236-T1 444 YCNETCAAGTYGFNCSNK-CP--CQNNSTCDPvfGFCNCLKGFQGIYCEEVA 492 334467888888888885.77..88888886544788888888888888765 PP >> EGF_Teneurin Teneurin-like EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 13.4 0.00011 0.29 1 29 [. 21 52 .. 20 53 .. 0.89 2 ! 14.6 14.2 1.4e-05 0.035 4 28 .. 68 94 .. 66 96 .. 0.91 3 ? 2.7 0.2 0.076 1.9e+02 18 27 .. 97 106 .. 96 109 .. 0.90 4 ! 23.0 11.7 3.5e-08 8.9e-05 4 30 .] 111 139 .. 108 139 .. 0.95 5 ? -1.0 0.1 1.1 2.8e+03 18 29 .. 140 151 .. 140 152 .. 0.87 6 ? 2.3 15.9 0.098 2.5e+02 4 28 .. 154 180 .. 147 181 .. 0.85 7 ? -1.6 1.5 1.7 4.4e+03 15 21 .. 195 201 .. 189 203 .. 0.85 8 ! 15.6 1.6 6.9e-06 0.018 11 29 .. 206 226 .. 204 227 .. 0.89 9 ? 0.5 0.1 0.38 9.7e+02 18 28 .. 230 240 .. 229 242 .. 0.89 10 ? -5.7 9.2 10 2.6e+04 1 20 [. 239 261 .. 239 262 .. 0.83 11 ? 4.8 14.6 0.017 42 4 28 .. 286 312 .. 279 314 .. 0.89 12 ! 8.1 2.9 0.0015 3.9 18 28 .. 315 325 .. 314 327 .. 0.92 13 ! 19.8 10.2 3.5e-07 0.00089 4 28 .. 329 355 .. 326 356 .. 0.94 14 ? 5.1 12.9 0.013 34 12 29 .. 384 401 .. 358 402 .. 0.79 15 ? -0.2 0.1 0.62 1.6e+03 17 28 .. 402 413 .. 402 415 .. 0.88 16 ! 5.7 3.5 0.0089 23 12 28 .. 430 446 .. 426 448 .. 0.78 17 ? -5.6 13.7 10 2.6e+04 5 29 .. 464 490 .. 445 491 .. 0.86 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00011 EGF_Teneurin 1 CppqC.gghGtC..kkGsCaCesGWkGeeCdv 29 C++ C +GtC +GsC C+ G++G+ C+ FUN_000236-T1 21 CSDECrCKNGTCspVDGSCYCSVGFTGAYCNK 52 888884479***999***************96 PP == domain 2 score: 14.6 bits; conditional E-value: 1.4e-05 EGF_Teneurin 4 qCgghGtC..kkGsCaCesGWkGeeCd 28 C+ GtC G+C C++G+ G +C+ FUN_000236-T1 68 NCSAYGTCnqFTGTCQCQPGYGGKHCE 94 7*******8889**************8 PP == domain 3 score: 2.7 bits; conditional E-value: 0.076 EGF_Teneurin 18 CesGWkGeeC 27 C++G+ G++C FUN_000236-T1 97 CKEGFFGPQC 106 ********** PP == domain 4 score: 23.0 bits; conditional E-value: 3.5e-08 EGF_Teneurin 4 qCgghGtC..kkGsCaCesGWkGeeCdve 30 +C ++ tC k+G+C C++GW+G +Cd++ FUN_000236-T1 111 LCQSNATCdeKDGTCDCQPGWTGVQCDNP 139 7**************************85 PP == domain 5 score: -1.0 bits; conditional E-value: 1.1 EGF_Teneurin 18 CesGWkGeeCdv 29 C s + G C+ FUN_000236-T1 140 CPSDYYGKNCNS 151 899999****85 PP == domain 6 score: 2.3 bits; conditional E-value: 0.098 EGF_Teneurin 4 qCgghGtC..kkGsCaCesGWkGeeCd 28 +C G C +G C+C W+Ge Cd FUN_000236-T1 154 KCQNGGSCesVDGNCTCVDEWQGEICD 180 57777889777899************8 PP == domain 7 score: -1.6 bits; conditional E-value: 1.7 EGF_Teneurin 15 sCaCesG 21 sC+C+++ FUN_000236-T1 195 SCLCKQN 201 8***997 PP == domain 8 score: 15.6 bits; conditional E-value: 6.9e-06 EGF_Teneurin 11 C..kkGsCaCesGWkGeeCdv 29 C ++G+C C+sG++G Cd+ FUN_000236-T1 206 ChtISGKCFCKSGFTGLLCDQ 226 66689**************98 PP == domain 9 score: 0.5 bits; conditional E-value: 0.38 EGF_Teneurin 18 CesGWkGeeCd 28 C G+ G +C+ FUN_000236-T1 230 CTAGFYGNQCS 240 99********8 PP == domain 10 score: -5.7 bits; conditional E-value: 10 EGF_Teneurin 1 CppqCgghGt.C..kkGsCaCes 20 C+ C+ +G C G C C FUN_000236-T1 239 CSKTCNCNGApCdvVTGACDCPA 261 9999**99975788899999965 PP == domain 11 score: 4.8 bits; conditional E-value: 0.017 EGF_Teneurin 4 qCgghGtC..kkGsCaCesGWkGeeCd 28 C G C G C C GW+G Cd FUN_000236-T1 286 TCQNSGSCdpVTGACSCTDGWQGRLCD 312 58889999988999************9 PP == domain 12 score: 8.1 bits; conditional E-value: 0.0015 EGF_Teneurin 18 CesGWkGeeCd 28 C++GW G++C+ FUN_000236-T1 315 CSEGWYGPGCN 325 **********9 PP == domain 13 score: 19.8 bits; conditional E-value: 3.5e-07 EGF_Teneurin 4 qCgghGtC..kkGsCaCesGWkGeeCd 28 +C+ +G C G+CaC+ GW G+ C+ FUN_000236-T1 329 DCSNRGSCyhVTGQCACSAGWVGPICN 355 8*******999***************8 PP == domain 14 score: 5.1 bits; conditional E-value: 0.013 EGF_Teneurin 12 kkGsCaCesGWkGeeCdv 29 G+C C +GW G +Cd FUN_000236-T1 384 VTGQCSCLEGWIGDKCDK 401 4578************97 PP == domain 15 score: -0.2 bits; conditional E-value: 0.62 EGF_Teneurin 17 aCesGWkGeeCd 28 +C G+ G +C FUN_000236-T1 402 RCVAGYYGYKCQ 413 699********7 PP == domain 16 score: 5.7 bits; conditional E-value: 0.0089 EGF_Teneurin 12 kkGsCaCesGWkGeeCd 28 G+C Ce+G+ C+ FUN_000236-T1 430 RNGQCYCEPGYANIYCN 446 57*********766665 PP == domain 17 score: -5.6 bits; conditional E-value: 10 EGF_Teneurin 5 CgghGtC..kkGsCaCesGWkGeeCdv 29 C + tC G C C G++G C++ FUN_000236-T1 464 CQNNSTCdpVFGFCNCLKGFQGIYCEE 490 6677777777788************96 PP >> DSL Delta serrate ligand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 14.8 0.022 57 1 46 [] 12 53 .. 12 53 .. 0.92 2 ? -2.6 15.7 3.9 1e+04 7 45 .. 60 95 .. 54 96 .. 0.80 3 ! 12.6 16.1 6.8e-05 0.17 1 46 [] 97 139 .. 97 139 .. 0.92 4 ! 10.8 16.8 0.00026 0.67 1 44 [. 140 180 .. 140 182 .. 0.91 5 ? 3.5 13.9 0.048 1.2e+02 1 45 [. 183 226 .. 183 227 .. 0.90 6 ? 3.3 9.4 0.058 1.5e+02 1 19 [. 230 248 .. 230 271 .. 0.74 7 ! 6.2 16.1 0.0068 17 4 45 .. 275 313 .. 272 314 .. 0.89 8 ! 11.3 16.3 0.00017 0.44 1 45 [. 315 356 .. 315 357 .. 0.90 9 ! 19.3 15.9 5.6e-07 0.0014 1 45 [. 358 401 .. 358 402 .. 0.91 10 ! 8.7 16.2 0.0012 2.9 1 45 [. 403 447 .. 403 448 .. 0.93 11 ! 7.0 12.9 0.0039 10 1 45 [. 449 490 .. 449 491 .. 0.92 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.022 DSL 1 CdenyyGekCskfCrprddkfghyrCde.nGkksCleGwtGekCeka 46 C+ yG Cs+ Cr ++ + C++ +G+ C+ G+tG +C+k+ FUN_000236-T1 12 CQPGSYGYLCSDECRCKNGT-----CSPvDGSCYCSVGFTGAYCNKP 53 88899***********9998.....98549**************986 PP == domain 2 score: -2.6 bits; conditional E-value: 3.9 DSL 7 GekCskfCrprddkfghyrCd.enGkksCleGwtGekCek 45 G +C+k C+ + +C+ +G+ +C +G+ G++Ce FUN_000236-T1 60 GLNCTKHCNCSAYG----TCNqFTGTCQCQPGYGGKHCEM 95 56788888776555....998359**************85 PP == domain 3 score: 12.6 bits; conditional E-value: 6.8e-05 DSL 1 CdenyyGekCskfCrprddkfghyrCd.enGkksCleGwtGekCeka 46 C+e ++G +C+ C + + +Cd ++G+ C +GwtG +C+++ FUN_000236-T1 97 CKEGFFGPQCRGKCLCQSNA----TCDeKDGTCDCQPGWTGVQCDNP 139 **************988777....9*9568**************986 PP == domain 4 score: 10.8 bits; conditional E-value: 0.00026 DSL 1 CdenyyGekCskfCrprddkfghyrCd.enGkksCleGwtGekCe 44 C + yyG++C++ C+ ++ +C+ +G+ +C ++w+Ge C+ FUN_000236-T1 140 CPSDYYGKNCNSKCKCQNGG----SCEsVDGNCTCVDEWQGEICD 180 999************99987....897369**************8 PP == domain 5 score: 3.5 bits; conditional E-value: 0.048 DSL 1 CdenyyGekCskfCrprddkfghyrCde.nGkksCleGwtGekCek 45 Cd yG +C++ C ++++ rC + +Gk C +G+tG C++ FUN_000236-T1 183 CDAWTYGLNCRNSCLCKQNQ--TERCHTiSGKCFCKSGFTGLLCDQ 226 99999*********999999..77898549**************98 PP == domain 6 score: 3.3 bits; conditional E-value: 0.058 DSL 1 CdenyyGekCskfCrprdd 19 C +yG++Csk+C+ + + FUN_000236-T1 230 CTAGFYGNQCSKTCNCNGA 248 999***********97765 PP == domain 7 score: 6.2 bits; conditional E-value: 0.0068 DSL 4 nyyGekCskfCrprddkfghyrCde.nGkksCleGwtGekCek 45 yG+kC++ C+ ++ +Cd+ +G sC +Gw+G C+k FUN_000236-T1 275 GSYGKKCQESCTCQNSG----SCDPvTGACSCTDGWQGRLCDK 313 56************998....9**648**************97 PP == domain 8 score: 11.3 bits; conditional E-value: 0.00017 DSL 1 CdenyyGekCskfCrprddkfghyrCd.enGkksCleGwtGekCek 45 C+e +yG +C++ C+ ++ +C +G+ C+ Gw G+ C+k FUN_000236-T1 315 CSEGWYGPGCNRSCDCSNRG----SCYhVTGQCACSAGWVGPICNK 356 ***************99877....675269**************86 PP == domain 9 score: 19.3 bits; conditional E-value: 5.6e-07 DSL 1 CdenyyGekCskfCrprddkfghyrCde.nGkksCleGwtGekCek 45 C e +G +Csk C+ r+d+ +Cd+ +G+ sCleGw G+kC+k FUN_000236-T1 358 CPEGKFGPGCSKQCQCRRDS--TENCDHvTGQCSCLEGWIGDKCDK 401 77888**************9..889*9549**************97 PP == domain 10 score: 8.7 bits; conditional E-value: 0.0012 DSL 1 CdenyyGekCskfCrprddkfghyrCd.enGkksCleGwtGekCek 45 C yyG kC+k+C+ + + + +Cd +nG+ C +G+ +C++ FUN_000236-T1 403 CVAGYYGYKCQKTCQCNLPR-MDAECDhRNGQCYCEPGYANIYCNE 447 8899************9999.899**9679**************86 PP == domain 11 score: 7.0 bits; conditional E-value: 0.0039 DSL 1 CdenyyGekCskfCrprddkfghyrCden.GkksCleGwtGekCek 45 C+ yG +Cs+ C ++++ +Cd+ G +Cl+G++G +Ce+ FUN_000236-T1 449 CAAGTYGFNCSNKCPCQNNS----TCDPVfGFCNCLKGFQGIYCEE 490 89999************999....***744**************96 PP >> EGF_PEAR1L Platelet endothelial aggregation receptor 1-like, EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 13.5 1.5 3.9e+03 8 48 .. 20 63 .. 9 64 .. 0.83 2 ! 16.2 10.8 4.3e-06 0.011 15 48 .. 72 106 .. 62 107 .. 0.77 3 ? 4.0 11.4 0.029 75 23 48 .. 124 149 .. 110 150 .. 0.92 4 ? -0.3 10.3 0.6 1.5e+03 22 48 .. 166 192 .. 152 193 .. 0.80 5 ? 1.9 8.2 0.13 3.3e+02 8 48 .. 197 239 .. 194 251 .. 0.73 6 ? -4.1 6.6 9.4 2.4e+04 19 48 .. 252 281 .. 242 282 .. 0.78 7 ? -1.0 20.2 1 2.6e+03 22 49 .] 298 325 .. 260 325 .. 0.85 8 ! 5.9 12.0 0.0074 19 16 48 .. 334 367 .. 327 368 .. 0.84 9 ! 17.3 6.1 2e-06 0.0052 22 48 .. 386 412 .. 373 413 .. 0.91 10 ! 8.0 6.7 0.0016 4.1 22 48 .. 432 458 .. 416 459 .. 0.85 11 ? -1.0 0.6 1 2.6e+03 24 36 .. 477 489 .. 463 495 .. 0.83 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.5 EGF_PEAR1L 8 lcaqec..vhGrcva.pnqcqcvpGwrGddcssecapGmwGpqc 48 lc+ ec G c c c G+ G c c G G +c FUN_000236-T1 20 LCSDECrcKNGTCSPvDGSCYCSVGFTGAYCNKPCVNGSAGLNC 63 8999963257999751468*******************999888 PP == domain 2 score: 16.2 bits; conditional E-value: 4.3e-06 EGF_PEAR1L 15 hGrcva.pnqcqcvpGwrGddcssecapGmwGpqc 48 +G c cqc pG+ G c +c G +Gpqc FUN_000236-T1 72 YGTCNQfTGTCQCQPGYGGKHCEMKCKEGFFGPQC 106 5566541457************************* PP == domain 3 score: 4.0 bits; conditional E-value: 0.029 EGF_PEAR1L 23 qcqcvpGwrGddcssecapGmwGpqc 48 c c pGw G c c +G +c FUN_000236-T1 124 TCDCQPGWTGVQCDNPCPSDYYGKNC 149 6**********************999 PP == domain 4 score: -0.3 bits; conditional E-value: 0.6 EGF_PEAR1L 22 nqcqcvpGwrGddcssecapGmwGpqc 48 +c cv w+G+ c c +G +c FUN_000236-T1 166 GNCTCVDEWQGEICDLMCDAWTYGLNC 192 57****************998888887 PP == domain 5 score: 1.9 bits; conditional E-value: 0.13 EGF_PEAR1L 8 lcaqecvhGrc.vapnqcqcvpGwrGddcss..ecapGmwGpqc 48 lc q+ rc +c c G+ G c c+ G +G qc FUN_000236-T1 197 LCKQNQT-ERChTISGKCFCKSGFTGLLCDQqiSCTAGFYGNQC 239 6666654.456234678999999999877652269999999999 PP == domain 6 score: -4.1 bits; conditional E-value: 9.4 EGF_PEAR1L 19 vapnqcqcvpGwrGddcssecapGmwGpqc 48 v c c G c+ c G +G +c FUN_000236-T1 252 VVTGACDCPAGKMLPICAESCPLGSYGKKC 281 555678888888888899999999999888 PP == domain 7 score: -1.0 bits; conditional E-value: 1 EGF_PEAR1L 22 nqcqcvpGwrGddcssecapGmwGpqcd 49 c c Gw+G c c+ G +Gp c+ FUN_000236-T1 298 GACSCTDGWQGRLCDKGCSEGWYGPGCN 325 57************************95 PP == domain 8 score: 5.9 bits; conditional E-value: 0.0074 EGF_PEAR1L 16 Grcv.apnqcqcvpGwrGddcssecapGmwGpqc 48 G c qc c Gw G c c G +Gp c FUN_000236-T1 334 GSCYhVTGQCACSAGWVGPICNKFCPEGKFGPGC 367 55642457*************************9 PP == domain 9 score: 17.3 bits; conditional E-value: 2e-06 EGF_PEAR1L 22 nqcqcvpGwrGddcssecapGmwGpqc 48 qc c+ Gw Gd c c G +G +c FUN_000236-T1 386 GQCSCLEGWIGDKCDKRCVAGYYGYKC 412 6************************99 PP == domain 10 score: 8.0 bits; conditional E-value: 0.0016 EGF_PEAR1L 22 nqcqcvpGwrGddcssecapGmwGpqc 48 qc c pG+ c ca G +G +c FUN_000236-T1 432 GQCYCEPGYANIYCNETCAAGTYGFNC 458 5***********************999 PP == domain 11 score: -1.0 bits; conditional E-value: 1 EGF_PEAR1L 24 cqcvpGwrGddcs 36 c+c+ G++G c FUN_000236-T1 477 CNCLKGFQGIYCE 489 9999999998885 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.5 0.77 2e+03 7 16 .. 12 21 .. 11 22 .. 0.83 2 ? 3.6 6.3 0.056 1.4e+02 1 22 [] 27 45 .. 27 45 .. 0.92 3 ? -2.1 0.3 3.5 8.9e+03 7 16 .. 54 63 .. 53 64 .. 0.79 4 ? 5.7 11.1 0.012 31 1 22 [] 69 88 .. 66 88 .. 0.88 5 ? 15.5 3.3 1e-05 0.026 1 22 [] 112 131 .. 112 131 .. 0.93 6 ? 11.1 6.1 0.00025 0.63 1 19 [. 155 171 .. 155 174 .. 0.89 7 ? -1.0 1.5 1.6 4e+03 7 20 .. 192 200 .. 189 200 .. 0.74 8 ? 3.0 1.0 0.086 2.2e+02 6 22 .] 205 219 .. 201 219 .. 0.91 9 ? -1.9 2.4 3.1 8e+03 1 16 [. 224 239 .. 224 240 .. 0.81 10 ? 2.6 4.5 0.12 2.9e+02 3 21 .. 246 262 .. 245 262 .. 0.87 11 ? 6.0 6.7 0.0094 24 1 22 [] 287 306 .. 287 306 .. 0.91 12 ? 11.3 6.8 0.00021 0.54 1 22 [] 330 349 .. 330 349 .. 0.99 13 ? -3.3 2.8 8.3 2.1e+04 15 18 .. 370 373 .. 366 375 .. 0.77 14 ? 7.4 1.8 0.0036 9.2 7 22 .] 381 394 .. 379 394 .. 0.89 15 ? 4.7 0.4 0.025 63 6 17 .. 402 413 .. 401 413 .. 0.93 16 ? -1.8 1.1 2.9 7.3e+03 15 19 .. 415 419 .. 414 419 .. 0.86 17 ? 3.7 2.2 0.051 1.3e+02 7 22 .] 427 440 .. 424 440 .. 0.88 18 ? -0.5 0.6 1.1 2.7e+03 4 17 .. 447 459 .. 446 459 .. 0.85 19 ? 3.3 5.1 0.072 1.8e+02 1 22 [] 464 483 .. 464 483 .. 0.92 20 ? -4.0 0.2 10 2.6e+04 5 12 .. 572 579 .. 571 579 .. 0.70 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.77 hEGF 7 CvdgvngykC 16 C+ g+ gy+C FUN_000236-T1 12 CQPGSYGYLC 21 8989999999 PP == domain 2 score: 3.6 bits; conditional E-value: 0.056 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+NG tC+ v+g +C C G+ FUN_000236-T1 27 CKNG-TCS-PVDG-SCYCSVGF 45 9***.***.9999.99999998 PP == domain 3 score: -2.1 bits; conditional E-value: 3.5 hEGF 7 CvdgvngykC 16 Cv+g+ g C FUN_000236-T1 54 CVNGSAGLNC 63 8888888888 PP == domain 4 score: 5.7 bits; conditional E-value: 0.012 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ GtC+ +g +CqC+pGy FUN_000236-T1 69 CSAYGTCN-QFTG-TCQCQPGY 88 66668***.8888.*******9 PP == domain 5 score: 15.5 bits; conditional E-value: 1e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++tC+ +g +C C+pG+ FUN_000236-T1 112 CQSNATCD-EKDG-TCDCQPGW 131 9*******.6688.******** PP == domain 6 score: 11.1 bits; conditional E-value: 0.00025 hEGF 1 ClNGGtCvdgvngykCqCp 19 C+NGG+C v+g C C FUN_000236-T1 155 CQNGGSCE-SVDG-NCTCV 171 ********.9999.99996 PP == domain 7 score: -1.0 bits; conditional E-value: 1.6 hEGF 7 CvdgvngykCqCpp 20 C ++C C++ FUN_000236-T1 192 CR-----NSCLCKQ 200 44.....6799986 PP == domain 8 score: 3.0 bits; conditional E-value: 0.086 hEGF 6 tCvdgvngykCqCppGy 22 +C+ +++g kC C++G+ FUN_000236-T1 205 RCH-TISG-KCFCKSGF 219 799.9999.*******9 PP == domain 9 score: -1.9 bits; conditional E-value: 3.1 hEGF 1 ClNGGtCvdgvngykC 16 C + +C+ g g++C FUN_000236-T1 224 CDQQISCTAGFYGNQC 239 6666789999999999 PP == domain 10 score: 2.6 bits; conditional E-value: 0.12 hEGF 3 NGGtCvdgvngykCqCppG 21 NG+ C+ v+g C Cp+G FUN_000236-T1 246 NGAPCD-VVTG-ACDCPAG 262 898999.7777.7****99 PP == domain 11 score: 6.0 bits; conditional E-value: 0.0094 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+N G+C+ v+g C+C G+ FUN_000236-T1 287 CQNSGSCD-PVTG-ACSCTDGW 306 ********.7777.7******9 PP == domain 12 score: 11.3 bits; conditional E-value: 0.00021 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+N+G+C +v+g +C C +G+ FUN_000236-T1 330 CSNRGSCY-HVTG-QCACSAGW 349 ********.****.*******9 PP == domain 13 score: -3.3 bits; conditional E-value: 8.3 hEGF 15 kCqC 18 +CqC FUN_000236-T1 370 QCQC 373 8*** PP == domain 14 score: 7.4 bits; conditional E-value: 0.0036 hEGF 7 CvdgvngykCqCppGy 22 C d+v+g +C+C +G+ FUN_000236-T1 381 C-DHVTG-QCSCLEGW 394 4.59***.*******9 PP == domain 15 score: 4.7 bits; conditional E-value: 0.025 hEGF 6 tCvdgvngykCq 17 +Cv g+ gykCq FUN_000236-T1 402 RCVAGYYGYKCQ 413 6**********8 PP == domain 16 score: -1.8 bits; conditional E-value: 2.9 hEGF 15 kCqCp 19 +CqC+ FUN_000236-T1 415 TCQCN 419 7***7 PP == domain 17 score: 3.7 bits; conditional E-value: 0.051 hEGF 7 CvdgvngykCqCppGy 22 C+ + ng +C C pGy FUN_000236-T1 427 CD-HRNG-QCYCEPGY 440 77.9999.*******9 PP == domain 18 score: -0.5 bits; conditional E-value: 1.1 hEGF 4 GGtCvdgvngykCq 17 tC g+ g+ C+ FUN_000236-T1 447 E-TCAAGTYGFNCS 459 5.9**9*******5 PP == domain 19 score: 3.3 bits; conditional E-value: 0.072 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+N+ tC+ v g C C G+ FUN_000236-T1 464 CQNNSTCD-PVFG-FCNCLKGF 483 ********.8888.9***9998 PP == domain 20 score: -4.0 bits; conditional E-value: 10 hEGF 5 GtCvdgvn 12 G Cv+ vn FUN_000236-T1 572 GGCVNEVN 579 46998776 PP >> SCIMP SCIMP protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 2.4e-05 0.061 10 80 .. 525 600 .. 521 645 .. 0.73 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 2.4e-05 SCIMP 10 iilavaiivvsvvlglilycvcrrll...rqGkkweiakplkqkerdeekmye.nvlnq.spvqlPplPPrgllsl 80 +++a+ +++v++vl l+l ++ r +l r Gk + k lk +er+ + e nv ++ p+++ P g +s+ FUN_000236-T1 525 LVIAIVVVMVTIVLVLVLVYLRRNRLivdRTGKSVSVRKLLKSQERQGGCVNEvNVKDDeGPDDVSVNPQHGDMSE 600 5778888888888888888888888777899***************999998878876515677766666554443 PP >> RIFIN Rifin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 2.5e-05 0.064 276 305 .. 515 545 .. 445 566 .. 0.76 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2.5e-05 RIFIN 276 eatyaslqtaiiaSi.vaivvIvLimvIIYl 305 ++++s+ ta++++i v++v IvL++v++Yl FUN_000236-T1 515 GTNTTSMATALVIAIvVVMVTIVLVLVLVYL 545 3455566666555550556779999999998 PP >> EGF_DL_JAG Delta-like/Jagged, EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 1.5 0.83 2.1e+03 12 24 .. 11 23 .. 6 25 .. 0.82 2 ? -3.1 4.2 4.9 1.3e+04 10 16 .. 24 30 .. 21 33 .. 0.86 3 ? 6.3 2.5 0.0055 14 2 25 .. 29 53 .. 28 54 .. 0.78 4 ? 3.3 9.2 0.048 1.2e+02 3 23 .. 73 94 .. 71 97 .. 0.81 5 ? -2.2 0.1 2.5 6.4e+03 12 19 .. 96 103 .. 94 106 .. 0.76 6 ? 9.9 7.6 0.00043 1.1 10 25 .. 124 139 .. 116 140 .. 0.90 7 ? -1.7 2.0 1.7 4.4e+03 10 16 .. 152 158 .. 149 161 .. 0.88 8 ? 0.9 5.7 0.27 7e+02 10 23 .. 167 180 .. 157 182 .. 0.90 9 ? 14.1 1.0 2.1e-05 0.053 10 26 .] 212 228 .. 212 228 .. 0.92 10 ? -4.9 3.0 10 2.6e+04 10 14 .. 242 246 .. 238 247 .. 0.74 11 ? -4.1 1.2 9.6 2.5e+04 11 14 .. 285 288 .. 284 289 .. 0.79 12 ? 12.1 4.0 8.2e-05 0.21 11 24 .. 300 313 .. 290 314 .. 0.89 13 ? 3.7 1.3 0.035 90 13 24 .. 315 326 .. 313 328 .. 0.89 14 ? 13.4 2.8 3.3e-05 0.084 10 24 .. 342 356 .. 333 357 .. 0.91 15 ? -5.8 3.5 10 2.6e+04 10 14 .. 370 374 .. 367 375 .. 0.76 16 ? 6.1 6.1 0.0062 16 10 24 .. 387 401 .. 387 403 .. 0.93 17 ? -6.8 3.8 10 2.6e+04 5 13 .. 412 418 .. 411 419 .. 0.49 18 ? 7.3 1.3 0.0027 6.8 10 24 .. 433 447 .. 430 449 .. 0.95 19 ? -4.4 1.2 10 2.6e+04 10 14 .. 461 465 .. 461 466 .. 0.80 20 ? 6.6 2.2 0.0046 12 11 24 .. 477 490 .. 468 491 .. 0.91 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.83 EGF_DL_JAG 12 nCeeGWgGlfCdq 24 +C++G G +C FUN_000236-T1 11 VCQPGSYGYLCSD 23 6**********75 PP == domain 2 score: -3.1 bits; conditional E-value: 4.9 EGF_DL_JAG 10 eCnCeeG 16 eC+C++G FUN_000236-T1 24 ECRCKNG 30 7999988 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0055 EGF_DL_JAG 2 HGtCskPw..eCnCeeGWgGlfCdqd 25 +GtCs P C C G G +C+++ FUN_000236-T1 29 NGTCS-PVdgSCYCSVGFTGAYCNKP 53 68886.44226*************96 PP == domain 4 score: 3.3 bits; conditional E-value: 0.048 EGF_DL_JAG 3 GtCskPw.eCnCeeGWgGlfCd 23 GtC++ +C+C++G gG C+ FUN_000236-T1 73 GTCNQFTgTCQCQPGYGGKHCE 94 888883238*********9997 PP == domain 5 score: -2.2 bits; conditional E-value: 2.5 EGF_DL_JAG 12 nCeeGWgG 19 +C+eG G FUN_000236-T1 96 KCKEGFFG 103 6****776 PP == domain 6 score: 9.9 bits; conditional E-value: 0.00043 EGF_DL_JAG 10 eCnCeeGWgGlfCdqd 25 +C C++GW G+ Cd++ FUN_000236-T1 124 TCDCQPGWTGVQCDNP 139 6*************75 PP == domain 7 score: -1.7 bits; conditional E-value: 1.7 EGF_DL_JAG 10 eCnCeeG 16 +C+C++G FUN_000236-T1 152 KCKCQNG 158 6****99 PP == domain 8 score: 0.9 bits; conditional E-value: 0.27 EGF_DL_JAG 10 eCnCeeGWgGlfCd 23 +C+C + W G Cd FUN_000236-T1 167 NCTCVDEWQGEICD 180 6************9 PP == domain 9 score: 14.1 bits; conditional E-value: 2.1e-05 EGF_DL_JAG 10 eCnCeeGWgGlfCdqdl 26 +C C+ G Gl+Cdq + FUN_000236-T1 212 KCFCKSGFTGLLCDQQI 228 5**************75 PP == domain 10 score: -4.9 bits; conditional E-value: 10 EGF_DL_JAG 10 eCnCe 14 +CnC+ FUN_000236-T1 242 TCNCN 246 69995 PP == domain 11 score: -4.1 bits; conditional E-value: 9.6 EGF_DL_JAG 11 CnCe 14 C+C+ FUN_000236-T1 285 CTCQ 288 9998 PP == domain 12 score: 12.1 bits; conditional E-value: 8.2e-05 EGF_DL_JAG 11 CnCeeGWgGlfCdq 24 C C +GW G +Cd+ FUN_000236-T1 300 CSCTDGWQGRLCDK 313 *************7 PP == domain 13 score: 3.7 bits; conditional E-value: 0.035 EGF_DL_JAG 13 CeeGWgGlfCdq 24 C eGW G C+ FUN_000236-T1 315 CSEGWYGPGCNR 326 *******99985 PP == domain 14 score: 13.4 bits; conditional E-value: 3.3e-05 EGF_DL_JAG 10 eCnCeeGWgGlfCdq 24 +C C GW+G C++ FUN_000236-T1 342 QCACSAGWVGPICNK 356 9************97 PP == domain 15 score: -5.8 bits; conditional E-value: 10 EGF_DL_JAG 10 eCnCe 14 +C+C FUN_000236-T1 370 QCQCR 374 89995 PP == domain 16 score: 6.1 bits; conditional E-value: 0.0062 EGF_DL_JAG 10 eCnCeeGWgGlfCdq 24 +C C eGW G Cd+ FUN_000236-T1 387 QCSCLEGWIGDKCDK 401 8*********99997 PP == domain 17 score: -6.8 bits; conditional E-value: 10 EGF_DL_JAG 5 CskPweCnC 13 C+k C+C FUN_000236-T1 412 CQKT--CQC 418 5554..555 PP == domain 18 score: 7.3 bits; conditional E-value: 0.0027 EGF_DL_JAG 10 eCnCeeGWgGlfCdq 24 +C Ce+G ++C++ FUN_000236-T1 433 QCYCEPGYANIYCNE 447 8*************8 PP == domain 19 score: -4.4 bits; conditional E-value: 10 EGF_DL_JAG 10 eCnCe 14 +C+C+ FUN_000236-T1 461 KCPCQ 465 5***8 PP == domain 20 score: 6.6 bits; conditional E-value: 0.0046 EGF_DL_JAG 11 CnCeeGWgGlfCdq 24 CnC +G G++C++ FUN_000236-T1 477 CNCLKGFQGIYCEE 490 ************86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (760 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1659 (0.0649442); expected 510.9 (0.02) Passed bias filter: 778 (0.0304561); expected 510.9 (0.02) Passed Vit filter: 163 (0.0063809); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.49u 0.40s 00:00:00.89 Elapsed: 00:00:00.42 # Mc/sec: 7240.95 // Query: FUN_000237-T1 [L=905] Description: FUN_000237 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-27 94.0 0.2 1.6e-26 93.2 0.2 1.4 1 RFX_DNA_binding RFX DNA-binding domain 1.4e-09 38.1 0.2 4.3e-09 36.5 0.2 1.8 1 RFX5_N RFX5 N-terminal domain 0.0059 17.1 0.0 0.012 16.1 0.0 1.4 1 Phage_tail_terminator_2 Phage tail termination protein ------ inclusion threshold ------ 0.079 13.9 0.0 0.19 12.7 0.0 1.6 1 Pox_D5 Poxvirus D5 protein-like 0.27 11.6 0.0 0.46 10.8 0.0 1.3 1 MID51-like_C Mitochondrial dynamics protein MID51 Domain annotation for each model (and alignments): >> RFX_DNA_binding RFX DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.2 0.2 3.1e-30 1.6e-26 1 78 [. 135 214 .. 135 215 .. 0.96 Alignments for each domain: == domain 1 score: 93.2 bits; conditional E-value: 3.1e-30 RFX_DNA_binding 1 qkfalqwlkknyeeaed.vsvpRsevYaeYvstcsklkl.kplnaasfgklvravFpnlktRRLgtrGqskYhYvglrlk 78 q++a++w+++++ee+++ +++p++evY+eY ++c++++ ++l+a +fgk+++ vFp++k RRLgtrG+skY+Y+g+++k FUN_000237-T1 135 QTQAFHWIRCHLEECDNnSTLPKHEVYDEYKAHCESMNAaRTLSAPDFGKIIKCVFPRVKARRLGTRGNSKYCYSGIQRK 214 57899*********99889*******************999************************************987 PP >> RFX5_N RFX5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.2 8.4e-13 4.3e-09 3 45 .. 70 112 .. 68 123 .. 0.90 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 8.4e-13 RFX5_N 3 LlqklknsiskavqskvegiLqevekFsDlekLYLYLqLPsGl 45 L q lk +sk +q++++ iL ev++ sD ekL LYL LP FUN_000237-T1 70 LEQALKSFVSKEIQERIQKILEEVQQLSDTEKLLLYLRLPGET 112 8899************************************654 PP >> Phage_tail_terminator_2 Phage tail termination protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 2.3e-06 0.012 17 105 .. 71 155 .. 64 170 .. 0.85 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 2.3e-06 Phage_tail_terminator_2 17 EdvvkallqplledvvlvctwLpddaleevedtepvlrvaRqgGeadkskrtdealvqiaaitesrsdSlrliefvrqvleeveeg 102 E+++k+ +++ +++ ++++ ++++ ++ dte++l R +Ge ++++ d + q i+++r++ + +++r lee +++ FUN_000237-T1 71 EQALKSFVSKEIQE---RIQKILEEVQ-QLSDTEKLLLYLRLPGETASDSLEDFDQNQSLPISTTRAEQTQAFHWIRCHLEECDNN 152 55555555554444...5567778887.9***************************************************999998 PP Phage_tail_terminator_2 103 gkv 105 ++ FUN_000237-T1 153 STL 155 765 PP >> Pox_D5 Poxvirus D5 protein-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 3.8e-05 0.19 19 59 .. 152 192 .. 144 218 .. 0.87 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 3.8e-05 Pox_D5 19 strvpsrylyaaYkawceknGykpvlskrtFqkrLkkhlee 59 +p+ +y+ Yka ce+ + ++ls F+k +k +++ FUN_000237-T1 152 NSTLPKHEVYDEYKAHCESMNAARTLSAPDFGKIIKCVFPR 192 5679*****************************99988875 PP >> MID51-like_C Mitochondrial dynamics protein MID51-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 9e-05 0.46 98 163 .. 283 348 .. 277 366 .. 0.76 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 9e-05 MID51-like_C 98 rfvvGg.ylsskvllevlekvlvasvnWPaigsllecvirPvvaseelklevkhekkleltiallpv 163 rf+vGg y+ssk+++ ++ + + +n P i+ l +++ P ee l ++ ++++ ++ lp FUN_000237-T1 283 RFLVGGsYVSSKSMA-AFVVMSSNELNTPHISHSLASLMTPLKQVEEQMLLTQKRRHSQQLVKKLPP 348 899987699999886.566788899****************99988877766666555555555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (905 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1030 (0.040321); expected 510.9 (0.02) Passed bias filter: 618 (0.0241926); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.45u 0.36s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 8529.46 // Query: FUN_000238-T1 [L=637] Description: FUN_000238 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-18 67.0 0.1 3.3e-18 66.0 0.1 1.6 1 Chromosome_seg Chromosome segregation during meiosis 2.5e-14 53.9 0.1 8.4e-14 52.3 0.1 2.0 1 DUF4210 Domain of unknown function (DUF4210) Domain annotation for each model (and alignments): >> Chromosome_seg Chromosome segregation during meiosis # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.0 0.1 2.6e-22 3.3e-18 2 53 .. 584 636 .. 583 637 .] 0.96 Alignments for each domain: == domain 1 score: 66.0 bits; conditional E-value: 2.6e-22 Chromosome_seg 2 LRYliHLrfcspkkgRiYLykdIRvvFanrvpDsdegk.LrsetetPsepkYs 53 L YliHLrf+s+k+ R+YL++dIRv+Fa++ pD +g + ++t++P+epkY+ FUN_000238-T1 584 LHYLIHLRFASSKSARLYLHTDIRVIFARQPPDLPTGVtFCTVTDGPTEPKYT 636 89**********************************878*************7 PP >> DUF4210 Domain of unknown function (DUF4210) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.3 0.1 6.6e-18 8.4e-14 1 72 [. 450 507 .. 450 508 .. 0.95 Alignments for each domain: == domain 1 score: 52.3 bits; conditional E-value: 6.6e-18 DUF4210 1 lvgSyeeSlLnGrmstlpskple.FvaeiGvlgkgkcksslrcpphlklpfeavfysledsdkksksedgsPY 72 l+g++eeS+LnGrm+ p+ ++e F+ae+G++g++ cp+h++lp++a+f+sl+d+++ sPY FUN_000238-T1 450 LLGNFEESVLNGRME--PVGAVEgFMAELGASGSF-------CPAHVTLPVKAYFFSLSDDNAP------SPY 507 78*************..******************.......******************9986......788 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (637 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 754 (0.0295165); expected 510.9 (0.02) Passed bias filter: 504 (0.0197299); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 6223.87 // Query: FUN_000238-T2 [L=506] Description: FUN_000238 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-18 67.4 0.1 2.4e-18 66.5 0.1 1.5 1 Chromosome_seg Chromosome segregation during meiosis 2e-14 54.3 0.2 6.2e-14 52.7 0.1 1.9 2 DUF4210 Domain of unknown function (DUF4210) Domain annotation for each model (and alignments): >> Chromosome_seg Chromosome segregation during meiosis # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.5 0.1 1.9e-22 2.4e-18 2 53 .. 453 505 .. 452 506 .] 0.96 Alignments for each domain: == domain 1 score: 66.5 bits; conditional E-value: 1.9e-22 Chromosome_seg 2 LRYliHLrfcspkkgRiYLykdIRvvFanrvpDsdegk.LrsetetPsepkYs 53 L YliHLrf+s+k+ R+YL++dIRv+Fa++ pD +g + ++t++P+epkY+ FUN_000238-T2 453 LHYLIHLRFASSKSARLYLHTDIRVIFARQPPDLPTGVtFCTVTDGPTEPKYT 505 89**********************************878*************7 PP >> DUF4210 Domain of unknown function (DUF4210) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.7 0.1 4.8e-18 6.2e-14 1 72 [. 319 376 .. 319 377 .. 0.95 2 ? -4.0 0.0 2 2.6e+04 37 59 .. 401 423 .. 395 427 .. 0.73 Alignments for each domain: == domain 1 score: 52.7 bits; conditional E-value: 4.8e-18 DUF4210 1 lvgSyeeSlLnGrmstlpskple.FvaeiGvlgkgkcksslrcpphlklpfeavfysledsdkksksedgsPY 72 l+g++eeS+LnGrm+ p+ ++e F+ae+G++g++ cp+h++lp++a+f+sl+d+++ sPY FUN_000238-T2 319 LLGNFEESVLNGRME--PVGAVEgFMAELGASGSF-------CPAHVTLPVKAYFFSLSDDNAP------SPY 376 78*************..******************.......******************9986......788 PP == domain 2 score: -4.0 bits; conditional E-value: 2 DUF4210 37 ksslrcpphlklpfeavfysled 59 + l p++ +++ +v y+++d FUN_000238-T2 401 QLTLFNPNKTVVKVFVVLYDFSD 423 55566788888888888888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (506 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 784 (0.0306909); expected 510.9 (0.02) Passed bias filter: 501 (0.0196124); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.34s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 4899.93 // Query: FUN_000239-T1 [L=84] Description: FUN_000239 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-30 104.1 4.0 3.8e-30 103.9 4.0 1.1 1 Ribosomal_S27e Ribosomal protein S27 ------ inclusion threshold ------ 0.036 15.2 0.0 0.043 14.9 0.0 1.1 1 Ig-like_Pom152_1 Nucleoporin pom152-like, first immunoglobul 0.083 13.0 3.2 0.34 11.0 1.4 2.1 2 Zn_ribbon_FGT1_1 FORGETTER1 first zinc ribbon domain 0.15 12.7 1.4 0.22 12.2 1.4 1.3 1 E7 E7 protein, Early protein 0.92 10.3 3.3 1.6 9.5 3.3 1.4 1 Lar_restr_allev Restriction alleviation protein Lar Domain annotation for each model (and alignments): >> Ribosomal_S27e Ribosomal protein S27 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 103.9 4.0 7.4e-34 3.8e-30 1 55 [] 28 82 .. 28 82 .. 0.99 Alignments for each domain: == domain 1 score: 103.9 bits; conditional E-value: 7.4e-34 Ribosomal_S27e 1 prskFldvkCpdCenetvvFshaatvvkCisCgkvLvePtGGkaklkaqilerlk 55 p+s+F+dvkCp+C+++t+vFsha+tvv+C+sC+ vL++PtGG+a+l++++++r+k FUN_000239-T1 28 PNSYFMDVKCPGCYKITTVFSHAQTVVLCVSCSMVLCQPTGGRARLTEGCSFRRK 82 89***************************************************97 PP >> Ig-like_Pom152_1 Nucleoporin pom152-like, first immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 8.4e-06 0.043 59 100 .. 12 53 .. 5 62 .. 0.86 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 8.4e-06 Ig-like_Pom152_1 59 ikkkaekksssslqktqslleipvkkpGlyrLekVlDeskle 100 ++++++k+++++l ++++ + + vk pG y+++ V + ++ FUN_000239-T1 12 VEEEKQKHKRKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTV 53 56778888999999*********************9887765 PP >> Zn_ribbon_FGT1_1 FORGETTER1 first zinc ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 1.4 6.7e-05 0.34 2 28 .. 34 61 .. 33 63 .. 0.80 2 ? 3.2 0.8 0.019 97 3 12 .. 54 63 .. 52 68 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 6.7e-05 Zn_ribbon_FGT1_1 2 qVrCAGCreiltV.apGltEFvCPkCql 28 V+C GC +i tV +++ t C +C++ FUN_000239-T1 34 DVKCPGCYKITTVfSHAQTVVLCVSCSM 61 69**********9556777777888876 PP == domain 2 score: 3.2 bits; conditional E-value: 0.019 Zn_ribbon_FGT1_1 3 VrCAGCreil 12 V C C+++l FUN_000239-T1 54 VLCVSCSMVL 63 89****9998 PP >> E7 E7 protein, Early protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 1.4 4.3e-05 0.22 31 72 .. 12 53 .. 5 65 .. 0.75 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 4.3e-05 E7 31 eeeeeedepeqkaktprrpYaveaaCarCekkvrlvvlatee 72 eee++++++++ ++ + Y +++ C+ C k+ ++ +a+ FUN_000239-T1 12 VEEEKQKHKRKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTV 53 3455555455666666666************99999988865 PP >> Lar_restr_allev Restriction alleviation protein Lar # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 3.3 0.00031 1.6 6 35 .. 37 66 .. 35 78 .. 0.73 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00031 Lar_restr_allev 6 CPfCGgaavlvesergeyegeyvaCkd..Cga 35 CP C++ +++ + +++ +v+C+ C+ FUN_000239-T1 37 CPGCYKITTVFSHAQTVVL--CVSCSMvlCQP 66 *************999753..66664455655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (84 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 984 (0.0385203); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.34s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 839.68 // Query: FUN_000240-T1 [L=157] Description: FUN_000240 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.044 14.4 2.0 0.063 13.9 2.0 1.3 1 NGF Nerve growth factor family 0.047 14.8 1.2 0.047 14.8 1.2 2.5 2 Yeast-kill-tox Yeast killer toxin 0.33 12.1 15.4 0.28 12.4 11.3 2.2 2 PLA2_inh Phospholipase A2 inhibitor Domain annotation for each model (and alignments): >> NGF Nerve growth factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 2.0 7.3e-06 0.063 25 91 .. 60 133 .. 42 154 .. 0.76 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 7.3e-06 NGF 25 irgkevtvlkevkinkvvlkqyfy....etkckeesksvksgcrGidkkkWnseckt...kqsfvraltikkek 91 ++++ v++ +e+k++++ l+ yfy et ck+++++ k+ c+ + + +c+ + f al +++++ FUN_000240-T1 60 VADTCVNISTEIKTETGFLRSYFYgcgtETMCKDAEENLKEICQNATREDHTPKCSVnccTTDFCVALDVTSDS 133 566779999***************99999****999999******99999998887511144566666665555 PP >> Yeast-kill-tox Yeast killer toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 1.2 5.5e-06 0.047 53 78 .. 44 71 .. 39 84 .. 0.81 2 ? -2.4 4.1 1.3 1.1e+04 59 74 .. 112 127 .. 83 133 .. 0.72 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 5.5e-06 Yeast-kill-tox 53 egsgcvgrsttmccp..adtccnintgf 78 e sgc s m cp adtc+ni t + FUN_000240-T1 44 EVSGCSKTSQQMTCPgvADTCVNISTEI 71 789************5559*****9865 PP == domain 2 score: -2.4 bits; conditional E-value: 1.3 Yeast-kill-tox 59 grsttmccpadtccni 74 + + cc +d c+ + FUN_000240-T1 112 PKCSVNCCTTDFCVAL 127 4566778888888766 PP >> PLA2_inh Phospholipase A2 inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.1 0.086 7.3e+02 34 54 .. 14 34 .. 5 40 .. 0.80 2 ? 12.4 11.3 3.3e-05 0.28 14 81 .. 51 124 .. 43 126 .. 0.82 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.086 PLA2_inh 34 vssaplslrlihknCfssdlC 54 ++sa ls ++ +++C d+ FUN_000240-T1 14 LVSAFLSTTVHSRKCAHLDVV 34 67999999999****887764 PP == domain 2 score: 12.4 bits; conditional E-value: 3.3e-05 PLA2_inh 14 egykeeCdsneDaCvtvllevssaplslrlihknCfssdlCk.....Lekldvn.igkelylrgkiaCCdeeeC 81 ++ + +C D+Cv++ +e+ + lr+ C++ +Ck L+++ n + ++ + + ++CC+ + C FUN_000240-T1 51 TSQQMTCPGVADTCVNISTEIKTETGFLRSYFYGCGTETMCKdaeenLKEICQNaTREDHTPKCSVNCCTTDFC 124 447889***********************************955544555544415678899*********999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1171 (0.0458407); expected 510.9 (0.02) Passed bias filter: 510 (0.0199648); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1617.44 // Query: FUN_000242-T1 [L=334] Description: FUN_000242 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0032 17.7 0.0 0.0063 16.7 0.0 1.5 1 Arnt_C Aminoarabinose transferase C-terminal domain Domain annotation for each model (and alignments): >> Arnt_C Aminoarabinose transferase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 2.5e-07 0.0063 49 103 .] 270 325 .. 262 325 .. 0.92 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 2.5e-07 Arnt_C 49 epekwiptleefaar.WragkkalAlispdtyeeLkaqglPmrvvardarrvvvak 103 +pe+ +++e f+++ W+ ++ + l+s ++ L+++ l+m+v++ d++rvvv+k FUN_000242-T1 270 NPERPCHQVEMFHKAgWTIVEPPVPLMSDSHSMWLSSKWLSMNVLMLDPKRVVVEK 325 6889999999997644**************************************86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (334 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 763 (0.0298689); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3221.89 // Query: FUN_000243-T1 [L=537] Description: FUN_000243 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-32 112.0 0.1 2.2e-31 110.1 0.0 1.9 2 Cupin_8 Cupin-like domain 1.4e-05 26.0 0.0 2.5e-05 25.2 0.0 1.4 1 JmjC JmjC domain, hydroxylase 0.0026 17.8 0.1 0.17 11.9 0.1 2.4 1 JmjC_2 JmjC domain Domain annotation for each model (and alignments): >> Cupin_8 Cupin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.1 0.0 2.6e-35 2.2e-31 1 246 [. 58 283 .. 58 287 .. 0.88 2 ? -1.5 0.1 0.3 2.6e+03 77 127 .. 465 515 .. 431 533 .. 0.50 Alignments for each domain: == domain 1 score: 110.1 bits; conditional E-value: 2.6e-35 Cupin_8 1 paeffreyvaknkPvvikgavkdwpavekwkdkeelldylkekagdvkvsveetpdgradalfenddltfvnpk.eeemtfkeflkeleaesdqka 95 p+ef+++yv +k v++ga+k+ +a+++w+d +ylk+k d +v++e ++ e++ ++ v +k ++t+++f+++++++ FUN_000243-T1 58 PQEFWTKYVLPSKAAVLRGAAKHGRAFTQWTD-----EYLKDKFADLEVRLEGKK--------EKSSIVPVGAKgVGRDTIGNFIDNYHNNG---- 136 78999**************************8.....*************97666........34456666554499*************83.... PP Cupin_8 96 ekalylqsaslrsefpelkedndlplateafgeepkavnlWiGnersvtslHkDhyeNlycvvrGrKrFtLfpPsdvenLyegpleepegqsvslv 191 + ly+ s+ p+++ + l + +++++ +v lW++ +++++ lHkD+y+ + c+ +G+K++ L++ + +++y+ + ++ +s++ FUN_000243-T1 137 -SNLYIVSELPTPMWPDVTVISPLTC--GLLKDRLVEVDLWMSGGGTKSILHKDAYNAINCLYNGTKKWKLIEYKYEDKIYKAWEPPQMVGGFSRI 229 .4577776666666677766555555..899999************************************************9754577889**** PP Cupin_8 192 dvdapdlekfprfreaakalevelepGdvLylPalWfHhVesldplniavnyWyd 246 +v+++dl k+p+++e+ v++++Gd+L+lP+ ++H+V+s+++ niav ++ FUN_000243-T1 230 NVLSVDLLKYPKVSEV-PWSFVTVNAGDCLFLPKSYYHQVSSYGTQNIAVSLLFS 283 ****************.9*************************999****98776 PP == domain 2 score: -1.5 bits; conditional E-value: 0.3 Cupin_8 77 emtfkeflkeleaesdqkaekalylqsaslrsefpelkedndlplateafg 127 em f+++ ++ ++++ +e++ + l+++++ ++e +d+p ++a+g FUN_000243-T1 465 EMLFNKLRDNDNNSDTVAEEEVRRNIDRALQRYLDWVREPEDIPQSQDAYG 515 233333333333332222222222223333333333333344444444444 PP >> JmjC JmjC domain, hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 3e-09 2.5e-05 20 111 .. 188 279 .. 175 282 .. 0.85 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 3e-09 JmjC 20 lySinylhfgapkvWyiipeekkeklekvlkkenskeqpdllrhlstlispkqleeegipvyrivqkpgefVivfpgayHavfnlgf.niaea 111 y + + ++ ++k W++i++++++k+ k++++ + + ++ ls + ++ ++e +p ++ ++g+ ++ + yH+v ++g+ nia++ FUN_000243-T1 188 AYNAINCLYNGTKKWKLIEYKYEDKIYKAWEPPQMVGGFSRINVLSVDLLKYPKVSE-VPWSFVTVNAGDCLFLPKSYYHQVSSYGTqNIAVS 279 455557789999*********************777777778888888888888777.**************************996466665 PP >> JmjC_2 JmjC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.9 0.1 2e-05 0.17 24 116 .. 169 279 .. 160 286 .. 0.60 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 2e-05 JmjC_2 24 vgsnvYatpggsegvgpHyDeydvfilQleGkkrWrvgk..............pkeeeqeekseeelklldef....epvedlvLepGDlLYlPrg 101 v+++++++ gg++++ H D y++ +G+k+W++ + +++ ++ + +++ll+ p +++++GD L+lP+ FUN_000243-T1 169 VEVDLWMSGGGTKSI-LHKDAYNAINCLYNGTKKWKLIEykyedkiykaweppQMVGGFSRINVLSVDLLKYPkvseVPWSFVTVNAGDCLFLPKS 263 556677777775554.58899998888899999999888666666666544221111112222222222221111212333457899********* PP JmjC_2 102 liHqgvaee.esltls 116 + Hq ++ + + +++s FUN_000243-T1 264 YYHQVSSYGtQNIAVS 279 ****998875555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (537 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 994 (0.0389117); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 5076.52 // Query: FUN_000243-T2 [L=463] Description: FUN_000243 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-32 111.4 0.0 1.6e-31 110.6 0.0 1.3 1 Cupin_8 Cupin-like domain 1.1e-05 26.3 0.0 2e-05 25.5 0.0 1.4 1 JmjC JmjC domain, hydroxylase 0.002 18.1 0.1 0.13 12.3 0.1 2.3 1 JmjC_2 JmjC domain Domain annotation for each model (and alignments): >> Cupin_8 Cupin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.6 0.0 1.9e-35 1.6e-31 1 246 [. 58 283 .. 58 287 .. 0.88 Alignments for each domain: == domain 1 score: 110.6 bits; conditional E-value: 1.9e-35 Cupin_8 1 paeffreyvaknkPvvikgavkdwpavekwkdkeelldylkekagdvkvsveetpdgradalfenddltfvnpk.eeemtfkeflkeleaesdqka 95 p+ef+++yv +k v++ga+k+ +a+++w+d +ylk+k d +v++e ++ e++ ++ v +k ++t+++f+++++++ FUN_000243-T2 58 PQEFWTKYVLPSKAAVLRGAAKHGRAFTQWTD-----EYLKDKFADLEVRLEGKK--------EKSSIVPVGAKgVGRDTIGNFIDNYHNNG---- 136 78999**************************8.....*************97666........34456666554499*************83.... PP Cupin_8 96 ekalylqsaslrsefpelkedndlplateafgeepkavnlWiGnersvtslHkDhyeNlycvvrGrKrFtLfpPsdvenLyegpleepegqsvslv 191 + ly+ s+ p+++ + l + +++++ +v lW++ +++++ lHkD+y+ + c+ +G+K++ L++ + +++y+ + ++ +s++ FUN_000243-T2 137 -SNLYIVSELPTPMWPDVTVISPLTC--GLLKDRLVEVDLWMSGGGTKSILHKDAYNAINCLYNGTKKWKLIEYKYEDKIYKAWEPPQMVGGFSRI 229 .4577776666666677766555555..899999************************************************9754577889**** PP Cupin_8 192 dvdapdlekfprfreaakalevelepGdvLylPalWfHhVesldplniavnyWyd 246 +v+++dl k+p+++e+ v++++Gd+L+lP+ ++H+V+s+++ niav ++ FUN_000243-T2 230 NVLSVDLLKYPKVSEV-PWSFVTVNAGDCLFLPKSYYHQVSSYGTQNIAVSLLFS 283 ****************.9*************************999****98776 PP >> JmjC JmjC domain, hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 2.3e-09 2e-05 20 111 .. 188 279 .. 175 282 .. 0.85 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 2.3e-09 JmjC 20 lySinylhfgapkvWyiipeekkeklekvlkkenskeqpdllrhlstlispkqleeegipvyrivqkpgefVivfpgayHavfnlgf.niaea 111 y + + ++ ++k W++i++++++k+ k++++ + + ++ ls + ++ ++e +p ++ ++g+ ++ + yH+v ++g+ nia++ FUN_000243-T2 188 AYNAINCLYNGTKKWKLIEYKYEDKIYKAWEPPQMVGGFSRINVLSVDLLKYPKVSE-VPWSFVTVNAGDCLFLPKSYYHQVSSYGTqNIAVS 279 455557789999*********************777777778888888888888777.**************************996466665 PP >> JmjC_2 JmjC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.1 1.5e-05 0.13 24 116 .. 169 279 .. 160 286 .. 0.61 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 1.5e-05 JmjC_2 24 vgsnvYatpggsegvgpHyDeydvfilQleGkkrWrvgk..............pkeeeqeekseeelklldef....epvedlvLepGDlLYlPrg 101 v+++++++ gg++++ H D y++ +G+k+W++ + +++ ++ + +++ll+ p +++++GD L+lP+ FUN_000243-T2 169 VEVDLWMSGGGTKSI-LHKDAYNAINCLYNGTKKWKLIEykyedkiykaweppQMVGGFSRINVLSVDLLKYPkvseVPWSFVTVNAGDCLFLPKS 263 556677777775554.68899999888899999999988666666666544221111112222222222221111212333457899********* PP JmjC_2 102 liHqgvaee.esltls 116 + Hq ++ + + +++s FUN_000243-T2 264 YYHQVSSYGtQNIAVS 279 ****998875555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (463 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 439 (0.0171854); expected 510.9 (0.02) Passed bias filter: 415 (0.0162458); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 4482.95 // Query: FUN_000244-T1 [L=424] Description: FUN_000244 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00044 19.9 0.1 0.049 13.1 0.0 2.5 3 ADI Arginine deiminase ------ inclusion threshold ------ 0.11 12.7 0.1 0.35 11.1 0.0 1.9 2 Arnt_C Aminoarabinose transferase C-terminal domain Domain annotation for each model (and alignments): >> ADI Arginine deiminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.8 0.0 0.0026 33 11 36 .. 121 146 .. 119 163 .. 0.87 2 ? -2.9 0.0 0.28 3.6e+03 237 249 .. 301 313 .. 255 323 .. 0.63 3 ! 13.1 0.0 3.8e-06 0.049 322 377 .] 361 416 .. 356 416 .. 0.91 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0026 ADI 11 leeaqkeHdeFaqvLreegveVlyle 36 l++aq e +eF+ vL +egv V ++ FUN_000244-T1 121 LKKAQTEVEEFCSVLHHEGVTVRRPD 146 789******************98765 PP == domain 2 score: -2.9 bits; conditional E-value: 0.28 ADI 237 raamhLDtvftmv 249 + mh D +f+++ FUN_000244-T1 301 PNPMHIDATFNII 313 4568888888776 PP == domain 3 score: 13.1 bits; conditional E-value: 3.8e-06 ADI 322 gsNvLaiapgvvvtydrntvtnekleeaGikVieipgseLsrGrGGarCmscplvR 377 +NvL ++p vv+ + ++ t + e Gi+ + ++ + GG +C sc ++R FUN_000244-T1 361 SMNVLMLDPKRVVVEKNEKTTQKMFESLGIQCVPVSLRFANSLGGGFHCWSCDVRR 416 59**********8877778888889999*********9999999********9998 PP >> Arnt_C Aminoarabinose transferase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 0.45 5.8e+03 77 93 .. 218 234 .. 203 240 .. 0.59 2 ? 11.1 0.0 2.8e-05 0.35 48 103 .] 320 376 .. 304 376 .. 0.91 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 0.45 Arnt_C 77 dtyeeLkaqglPmrvva 93 + ++L +q Pmr v FUN_000244-T1 218 TMSDDLYDQLYPMRTVE 234 33445555556777664 PP == domain 2 score: 11.1 bits; conditional E-value: 2.8e-05 Arnt_C 48 qepekwiptleefaar.WragkkalAlispdtyeeLkaqglPmrvvardarrvvvak 103 ++p++ +++e f+++ W+ k+ li+ + ++++ l+m+v++ d++rvvv+k FUN_000244-T1 320 SNPDRPCHQIEMFHKAgWTVVKPPNPLIPDTHPLWMSSKWLSMNVLMLDPKRVVVEK 376 68999999****98644***********9999999********************86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (424 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 726 (0.0284204); expected 510.9 (0.02) Passed bias filter: 692 (0.0270894); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4073.68 // Query: FUN_000245-T1 [L=358] Description: FUN_000245 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.011 16.4 0.2 0.027 15.1 0.1 1.8 2 Alpha_adaptin_C Alpha adaptin AP2, C-terminal domain Domain annotation for each model (and alignments): >> Alpha_adaptin_C Alpha adaptin AP2, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.1 1.1e-06 0.027 18 88 .. 149 220 .. 147 241 .. 0.92 2 ? -2.6 0.0 0.33 8.4e+03 34 48 .. 265 279 .. 234 319 .. 0.60 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.1e-06 Alpha_adaptin_C 18 qlggapreaqkifglkkankeideetvrkvleGfrlsileevdpnpenivgagvlhtssa.kvgcLlrlepn 88 ql++ ++e + f++++a+ +++ e+ r+ +e +++++ e+ ++ ++ +++++ + k+ + rl FUN_000245-T1 149 QLSNVHQELLHLFAIHDAKYQMECERERRTVEDIKTRLHEQLLSKMARRKASEIFEMERKrKIEEMKRLTDT 220 89********************************************************99999999998755 PP == domain 2 score: -2.6 bits; conditional E-value: 0.33 Alpha_adaptin_C 34 kankeideetvrkvl 48 +++ke+ + +r+ FUN_000245-T1 265 EEHKEMMLQEIRRRP 279 333344444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (358 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2478 (0.0970053); expected 510.9 (0.02) Passed bias filter: 537 (0.0210217); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3515.40 // Query: FUN_000246-T1 [L=136] Description: FUN_000246 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.7 5.4 0.25 11.9 5.4 1.5 1 DUF1542 Domain of Unknown Function (DUF1542) 0.16 12.5 1.4 0.22 12.1 1.4 1.2 1 MetOD1 Methanogen output domain 1 0.29 10.3 5.0 0.35 10.0 5.0 1.0 1 Med17 Subunit 17 of Mediator complex Domain annotation for each model (and alignments): >> DUF1542 Domain of Unknown Function (DUF1542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 5.4 2.9e-05 0.25 7 42 .. 13 48 .. 7 73 .. 0.84 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 2.9e-05 DUF1542 7 aeidqkaeekkaeInnnpdaTteEkqeAinqvnqak 42 + +q+a+ek+ I+n+ T+++k++A+++ + + FUN_000246-T1 13 EVMNQEAQEKTRRIKNSASRTSDQKDDAKSKAIDML 48 6689*************************9876555 PP >> MetOD1 Methanogen output domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 1.4 2.6e-05 0.22 33 91 .. 15 79 .. 2 84 .. 0.73 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 2.6e-05 MetOD1 33 lkpkfekelkekkt......ekekkdsenileaylewlselfgnfgietetkkdedrivleftnC 91 ++++ ++++ k+ +++++ +++ ++++++ ++l++ f i + + +e+ +l++ nC FUN_000246-T1 15 MNQEAQEKTRRIKNsasrtsDQKDDAKSKAIDMLVDVQKQLLDVFAIAKIRDVKERMNHLKVMNC 79 3333333333332244455567777888999********************************** PP >> Med17 Subunit 17 of Mediator complex # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 5.0 4.1e-05 0.35 55 112 .. 2 87 .. 1 90 [. 0.79 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 4.1e-05 Med17 55 tEesLreeiekeeeskeeedke...........eeeeeeeeeeiDvve.edk.................eltqeefekarkelieqi 112 +Ee Lr++i+ke +++e+++k+ +++++ +++ iD++ + ++++ ++++ r++++++i FUN_000246-T1 2 QEELLRKSIQKEVMNQEAQEKTrriknsasrtsDQKDDAKSKAIDMLVdV-QkqlldvfaiakirdvkeRMNHLKVMNCRQNMLREI 87 7999***********99999997887777777777777777777776642.257999999999988887777779999999999988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (136 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2167 (0.0848307); expected 510.9 (0.02) Passed bias filter: 809 (0.0316696); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1352.90 // Query: FUN_000247-T1 [L=1126] Description: FUN_000247 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-65 220.2 0.1 6.9e-34 118.2 0.0 2.2 2 Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-prop 1.8e-49 169.0 6.2 1.5e-21 77.6 0.0 3.7 4 PQQ_2 Outer membrane protein assembly factor Ba 6.2e-47 160.6 0.0 1.1e-46 159.7 0.0 1.4 1 Aldo_ket_red Aldo/keto reductase family 2.7e-39 136.1 0.3 6.7e-39 134.8 0.3 1.7 1 Cupin_8 Cupin-like domain 3.5e-19 69.4 0.3 2.2e-05 23.8 0.0 6.1 6 PQQ Glucose/ethanol/alcohol dehydrogenase, be 5.3e-09 36.3 0.0 0.0007 19.5 0.0 3.2 4 Beta-prop_EML_2 Echinoderm microtubule-associated protein 1.2e-08 35.2 0.1 8.1e-05 22.6 0.0 3.2 3 Beta-prop_EMC1_N EMC1 N-terminal beta-propeller domain 2e-08 34.0 0.0 0.00043 19.9 0.1 2.4 2 Beta-prop_THOC3 THOC3 beta-propeller domain 2.7e-07 30.7 0.0 1.3e-06 28.4 0.0 2.2 1 JmjC_2 JmjC domain 6.8e-07 29.5 5.7 0.071 13.1 0.1 4.5 5 Beta-prop_CGLA Lambda-carrageenase beta-propeller domain 2.3e-05 24.3 0.3 0.026 14.3 0.1 2.1 2 Beta-prop_WDR5 WDR5 beta-propeller domain 5e-05 23.0 0.0 0.039 13.5 0.0 2.6 2 WDR55 WDR55 0.0012 19.0 0.3 0.23 11.6 0.1 2.4 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 0.0046 17.3 0.6 10 6.5 0.1 4.0 4 SSL_N Strictosidine synthase-like, N-terminal 0.0064 17.2 0.0 4 8.2 0.0 4.0 4 ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 0.0068 17.3 0.3 0.022 15.7 0.1 2.0 1 JmjC JmjC domain, hydroxylase ------ inclusion threshold ------ 0.028 14.2 0.0 1.1 8.9 0.0 2.3 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 0.05 13.8 0.2 0.31 11.3 0.1 2.4 2 Cupin_2 Cupin domain 0.06 13.9 0.0 4.1 8.0 0.0 3.4 4 SUKH-4 SUKH-4 immunity protein 0.07 13.8 0.3 0.32 11.7 0.0 2.3 1 DUF7957 Domain of unknown function (DUF7957) 0.55 10.8 4.9 3.8 8.1 0.4 3.8 4 PD40 WD40-like Beta Propeller Repeat Domain annotation for each model (and alignments): >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.1 0.0 5.2e-33 6.3e-30 11 192 .. 777 961 .. 773 962 .. 0.87 2 ! 118.2 0.0 5.6e-37 6.9e-34 57 225 .. 950 1119 .. 949 1124 .. 0.94 Alignments for each domain: == domain 1 score: 105.1 bits; conditional E-value: 5.2e-33 Beta-prop_ACSF4 11 vvaktvdksselvvvgSHsgkivcvdletgeviweielpdriEssacvskdgklvvvGcydgklycldlatgeilwkfktgdaiKsspvidses 104 v++++vd +++++ S ++ i ++d+ +g++ w++ d+ s++++++dg+ v+ G+ d++l +ld+ +g+++wkf+tg+ai ss + + FUN_000247-T1 777 VLIERVDLRDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRVGP-D 869 5556677788899999999**************************99999**********************************99999976.5 PP Beta-prop_ACSF4 105 glvvvgsydknlyaldvesgklvwklklggsifsspllskskesvlvatldG...tvaalseesgeilWkvklesPiFsspvilsde..vvva 192 g++++g+ d+++ya++ + g+l+wk +lg++i ssp++ ++ +++++++++ +v+al+ ++geilW +++ P+Fssp+i+ d v+++ FUN_000247-T1 870 GSLYFGCLDGYFYAINPD-GSLKWKQNLGEEIWSSPAVLSNGKTLFIGSMADgaaNVFALNCATGEILWDNETKGPVFSSPTISYDGktVFFC 961 6889***********995.9****************999999999999985323378999999******************998653225555 PP == domain 2 score: 118.2 bits; conditional E-value: 5.6e-37 Beta-prop_ACSF4 57 cvskdgklvvvGcydgklycldlatgeilwkfktgdaiKsspvidsesglvvvgsydknlyaldvesgklvwklklggsifsspllskskes 148 ++s dgk v++ ++d + y+++ ++g+ lw f+t++ai sspv+ + g+++vgs ++n+ya+d +gk++w+++ +g++fssp + + + FUN_000247-T1 950 TISYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIA-PDGH 1040 68999*********************************************************************************5.6899 PP Beta-prop_ACSF4 149 vlvatldGtvaalseesgeilWkvklesPiFsspvilsde.vvvaevdgtvlcls.eegeklwsvktkgpiFsspvlvk 225 +++++ +G+v+al +++g+++W++k+es + ssp + ++ ++++ +d +++l+ e+g+ +w++kt+gp+ +p++ + FUN_000247-T1 1041 IFIGSGEGEVLALRQTDGSLVWSFKTESAVWSSPRLGKNGvLFIGGIDTYLYALRsEDGQVVWKYKTDGPVVGTPLITR 1119 ************************************87753789**********8578**************9999864 PP >> PQQ_2 Outer membrane protein assembly factor BamB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.5 0.0 2.2e-12 2.7e-09 32 147 .. 785 897 .. 771 899 .. 0.85 2 ! 77.6 0.0 1.3e-24 1.5e-21 3 183 .. 879 1052 .. 877 1052 .. 0.84 3 ! 42.0 0.2 9.3e-14 1.1e-10 28 102 .. 991 1067 .. 986 1076 .. 0.89 4 ! 39.3 0.2 6.3e-13 7.6e-10 2 77 .. 1047 1123 .. 1046 1126 .] 0.89 Alignments for each domain: == domain 1 score: 37.5 bits; conditional E-value: 2.2e-12 PQQ_2 32 dggrlfvasgggelvaldaetGkllWrqalsgevlga.Plvaggrv.vvvaadgtlialdakdGrrlWslqrseealalrsssspavvgdtvvlgf 125 +++l+ s+ ++a+da +Gk W++ e ++ ++++g+v ++ ++d++l+alda +G++ W + ++ + ++ss+++ ++ +++g+ FUN_000247-T1 785 RDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKcAFNSDGTVvYCGTDDKSLRALDAVSGSLIWKFSTG----GAITSSTRVGPDGSLYFGC 876 6889************************99555555546666666659999999***************8888....55667777777899***** PP PQQ_2 126 ssgklvaldpktGkvlweasva 147 +g +a++p+ G++ w +++ FUN_000247-T1 877 LDGYFYAINPD-GSLKWKQNLG 897 *********88.******9985 PP == domain 2 score: 77.6 bits; conditional E-value: 1.3e-24 PQQ_2 3 gtvaaldaatGaelWrvdlerk.lgggvav.dggrlfva...sgggelvaldaetGkllWrqalsgevlgaPlv..aggrvvvvaadgtliald 89 g +a+++ +G++ W+++l+++ +++ ++ +g++lf++ +g + + al+ +tG++lW ++ +g+v ++P++ +g++v+ + d +a++ FUN_000247-T1 879 GYFYAINP-DGSLKWKQNLGEEiWSSPAVLsNGKTLFIGsmaDGAANVFALNCATGEILWDNETKGPVFSSPTIsyDGKTVFFCSFDANCYAFN 971 56679997.8*********655155555667999****9666699**************************9973368899************* PP PQQ_2 90 akdGrrlWslqrseealalrsssspavvgdtvvlgfssgklvaldpktGkvlweasvaaprgtseiervgdvtgrpvva.ggrVyassgqgrlv 182 +++G++lW +q+ a+ ss+ v++t+++g s g+++a+d +tGkv w + +g g+++++p++a +g +++ sg+g+++ FUN_000247-T1 972 TESGKELWVFQTD---SAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTR-----EGK------GELFSSPFIApDGHIFIGSGEGEVL 1051 *********7766...3555666666679************************99.....333......3469999999555999999999886 PP PQQ_2 183 a 183 a FUN_000247-T1 1052 A 1052 5 PP == domain 3 score: 42.0 bits; conditional E-value: 9.3e-14 PQQ_2 28 gvav.dggrlfvasgggelvaldaetGkllWrqalsgevlgaPlva.ggrvvvvaadgtlialdakdGrrlWslqrs 102 v++ +g+lfv+s +g ++a+d +tGk+ W+ + +ge+ ++P++a +g++++ +++g++ al ++dG+++Ws++++ FUN_000247-T1 991 PVVSkVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIApDGHIFIGSGEGEVLALRQTDGSLVWSFKTE 1067 4577789************************************99878999**********************5544 PP == domain 4 score: 39.3 bits; conditional E-value: 6.3e-13 PQQ_2 2 dgtvaaldaatGaelWrvdlerk.lgggvavdggrlfvasgggelvaldaetGkllWrqalsgevlgaPlvaggrvv 77 +g+v al +++G+++W+++ e + +++ + ++g+lf+++ l+al e+G ++W+++ +g+v+g+Pl+++++ v FUN_000247-T1 1047 EGEVLALRQTDGSLVWSFKTESAvWSSPRLGKNGVLFIGGIDTYLYALRSEDGQVVWKYKTDGPVVGTPLITREHAV 1123 799***************9966516666667****************************************999875 PP >> Aldo_ket_red Aldo/keto reductase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.7 0.0 9.3e-50 1.1e-46 1 286 [. 469 730 .. 469 733 .. 0.94 Alignments for each domain: == domain 1 score: 159.7 bits; conditional E-value: 9.3e-50 Aldo_ket_red 1 klglGtwqlgggegrvskeealetlkaaldaGirfiDtAevYgdgksEellgealkksrvkrekvfiatKvkgdgpwksglskeeirksleeslkr 96 klg+Gt+ l+ e+ + + al aG+r+iD+A++Y +Ee +g al+ks +re++fi++Kv ++ l ++e +s+eeslk+ FUN_000247-T1 469 KLGFGTAGLF--------EDTKSSVLLALNAGYRLIDSAQAY----NEEHVGFALEKSGIPREDIFIVSKV-----HPRFLGYQETLQSVEESLKN 547 5788888888........788889999***************....*************************.....999999************** PP Aldo_ket_red 97 lgtdylDllylHwpdpstp...............ieetlkaLeelkkeGkiraiGvSnfdieqiekakkkkkipivavqveynllrrreeeellel 177 l+++y+Dl ++H d++ e+ +kaLe l+ + kir+iGvSnf++++++++++ + i +++vq+++ ++ ++++e +e+ FUN_000247-T1 548 LKVSYIDLMLIHSMDCDEGpgahltcakgepkgtWEDSWKALESLVGKNKIRSIGVSNFEVKDLQRLLEIANIHPSVVQNSFDPF--NQDRETREF 641 ******************99*****************************************************************..********* PP Aldo_ket_red 178 cekkgigliaysplagGlltkkktkdedkgskeeredlkktslnlealealeelakehgvslaevalryalkkpkvtvvivgvsnleqleenlaal 273 c+k++i+++a+s+l+ + + ++ ++++ + +e l+++a++ + s+ ++++++ l ++ i+ ++n++++e n+ FUN_000247-T1 642 CKKNNIQFMAHSTLGDSWKR----EGLPQNP-------------VLSDEGLRKIATQFDASVPQLVIKWCL---EQAICIPRSRNPNHIETNFHLS 717 ***************66655....5555544.............4899***********************...899******************* PP Aldo_ket_red 274 efelsdeevarid 286 ++ l+ + ++++ FUN_000247-T1 718 HVHLNNHDREYFK 730 9999988776665 PP >> Cupin_8 Cupin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 134.8 0.3 5.5e-42 6.7e-39 3 249 .. 168 388 .. 166 390 .. 0.86 Alignments for each domain: == domain 1 score: 134.8 bits; conditional E-value: 5.5e-42 Cupin_8 3 effreyvaknkPvvikgavkdwpavekwkdkeelldylkekagdvkvsveetpdgradalfenddltfvnpkeeemtfkeflkeleaesdqkaeka 98 +f++ ++ k++P++++ga+k+wpav+ w++ +yl++k+g+v + v+ t+ +++ ++ p++++m++ efl ++++ + FUN_000247-T1 168 DFYEHFLRKRRPLIMRGAIKNWPAVKYWSE----ESYLQQKYGHVIFDVQLTK-------KYEGEF----PAKKTMNLTEFLGIYKNK-------Q 241 67899***********************98....79*************8888.......455444....999**************9.......6 PP Cupin_8 99 lylqsaslrsefpelkedndlp...lateafgeepkavnlWiGnersvtslHkDhyeNlycvvrGrKrFtLfpPsdvenLyegpleepegqsvslv 191 +yl++ +s ++ +d +p ++e++++ ++++l + +++++s H D yeNl+ v+ G+K+ ++ +P+ +e+ y+++ ++ + s + FUN_000247-T1 242 VYLDCPFPHS---DMIQDIFVPyclQCEEVMNT-IASTHLLFSSGNTSSSCHMDGYENLLSVIAGTKEILVADPKYIEYFYPRNH--TTVNIESPI 331 9998655555...44555444422235566664.7899*********************************************94..33445567* PP Cupin_8 192 dvdapdlekfprfreaakalevelepGdvLylPalWfHhVesldplniavnyWydmsf 249 d++a+dlekfp++ e ++v l++Gd+Ly+P+ W+HhV+s++ nia+ W++++ FUN_000247-T1 332 DPEAVDLEKFPKLAEI-PFHKVVLKAGDILYIPQHWWHHVRSYNCPNIAISLWFHPFA 388 ****************.**************************767********9976 PP >> PQQ Glucose/ethanol/alcohol dehydrogenase, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 1.8e-08 2.2e-05 57 153 .. 786 867 .. 760 876 .. 0.83 2 ! 6.8 0.0 0.0027 3.3 534 584 .. 896 949 .. 885 956 .. 0.71 3 ! 6.9 0.0 0.0024 2.9 57 579 .. 955 986 .. 947 993 .. 0.62 4 ! 15.9 0.0 4.5e-06 0.0054 47 86 .. 985 1026 .. 982 1033 .. 0.84 5 ? 2.6 0.0 0.048 58 55 87 .. 1036 1068 .. 1025 1075 .. 0.81 6 ! 7.7 0.0 0.0014 1.7 538 585 .. 1070 1116 .. 1063 1123 .. 0.84 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 1.8e-08 PQQ 57 dgvLylctptnrvvAldaatGeekWrfdpkvkekkslekltcRGvayweakaktaecakriilatadarLialdaatGkpcegFGekGvvdlkegl 152 d +Lyl++ +++++A da +G+ kW++ + + +c a+ ++ + ++ +t d+ L alda +G+++ +F ++G++ ++++ FUN_000247-T1 786 DSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGG-----SKC---AFNSD-------GTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRV 866 789************************8744322.....222...33333.......478999**************************9877766 PP PQQ 153 g 153 g FUN_000247-T1 867 G 867 5 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0027 PQQ 534 tgtpnlggpl.vtagglvfigatade..rlrAfdkktGeelwetelpagaqatp 584 +g+ +p + +g+ +fig++ad + A++ +tGe lw+ e + ++p FUN_000247-T1 896 LGEEIWSSPAvLSNGKTLFIGSMADGaaNVFALNCATGEILWDNETKGPVFSSP 949 555555555404567889999998853388999999999999998887777766 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0024 PQQ 57 dgvLylctptnrvvAldaatGeekWrfdpkvkekkslekltcRGvayweakaktaecakriilatadarLialdaatGkpcegFGekGvvdlkegl 152 + ++++c+ + + +A + ++G+e+W+f+++ FUN_000247-T1 955 GKTVFFCSFDANCYAFNTESGKELWVFQTDS----------------------------------------------------------------- 985 4566667777777777777777777766554................................................................. PP PQQ 153 geaepgeygvtspPvvvgdtvvvggsvtdnqstkepsGvvrafDartGklkWafdpgeeeaeaepedeetytrgtanvWavlsaDeelglvYlptg 248 FUN_000247-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 249 saspDfyGgdRkggdnlyasSvVALdaatGkvvWhfQtvhhDlwDyDlpaqPvLvditkdgkkipavaqvtKqgllFvldRetGeplfpveerpvp 344 FUN_000247-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 345 qsdvpgeklspTQPfptlpalpaqdlteedlwgltpedqaacreklkklryeglftPpseqgtlvlPgalGgvnwggvaidpetgllivnsnelpa 440 FUN_000247-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 441 vvklvpreeaealekkkeakgageesevkpqegtpyaverkpllsplglpcvkPPwgeltaidlntgeiaWqvplGttedsaplplkvklpletgt 536 FUN_000247-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 537 pnlggplvtagglvfigataderlrAfdkktGeelwetelpag 579 + FUN_000247-T1 986 ------------------------------------------A 986 ..........................................3 PP == domain 4 score: 15.9 bits; conditional E-value: 4.5e-06 PQQ 47 safeatPl..vvdgvLylctptnrvvAldaatGeekWrfdpk 86 sa++++P+ +vdg+L++ +++++++A+d atG+ kW+ + k FUN_000247-T1 985 SAIQSSPVvsKVDGTLFVGSSEGNIYAVDSATGKVKWTREGK 1026 5677888733689************************98765 PP == domain 5 score: 2.6 bits; conditional E-value: 0.048 PQQ 55 vvdgvLylctptnrvvAldaatGeekWrfdpkv 87 + dg++++ +++++v+Al + G +W+f+++ FUN_000247-T1 1036 APDGHIFIGSGEGEVLALRQTDGSLVWSFKTES 1068 458899999999999999999999999998765 PP == domain 6 score: 7.7 bits; conditional E-value: 0.0014 PQQ 538 nlggplvtagglvfigataderlrAfdkktGeelwetelpagaqatpm 585 +p + + g++fig+ d +l+A+ +++G+++w+++ + +tp FUN_000247-T1 1070 VWSSPRLGKNGVLFIGGI-DTYLYALRSEDGQVVWKYKTDGPVVGTPL 1116 55667777899****996.9******************9999999885 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 5.7e-07 0.0007 16 109 .. 792 885 .. 784 898 .. 0.88 2 ? 4.9 0.0 0.017 20 32 113 .. 890 975 .. 886 1000 .. 0.77 3 ! 10.4 0.0 0.00035 0.43 13 100 .. 958 1045 .. 950 1051 .. 0.80 4 ! 6.9 0.0 0.0042 5.1 16 108 .. 1003 1094 .. 998 1112 .. 0.81 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 5.7e-07 Beta-prop_EML_2 16 agdDktvrlWdlekkklvakv.klekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylY 108 +dD+ ++ +d+ + k+ +k+ + ++ + +af++dg+++ +G++d s+ lda +++ + ++++ s + pdg+ L g+ d+++y FUN_000247-T1 792 SSDDHWIYAFDAVSGKMKWKYgTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRVGPDGS-LYFGCLDGYFYAI 884 69******************9555677788*************************************************8.5669999998866 PP Beta-prop_EML_2 109 d 109 + FUN_000247-T1 885 N 885 5 PP == domain 2 score: 4.9 bits; conditional E-value: 0.017 Beta-prop_EML_2 32 lvakvklekea.rsvafspdgkllavGlk.dG..svlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskk 113 l +k +l++e+ +s a+ ++gk+l +G+ dG +v+ l+ t+e + +++ s + s dgk++ +s d + y ++++++ FUN_000247-T1 890 LKWKQNLGEEIwSSPAVLSNGKTLFIGSMaDGaaNVFALNCATGEILWDNETKGPVFSSPTISYDGKTVFFCSFDANCYAFNTESG 975 5677788777647889999********843662256668889999999999999999*************************8754 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00035 Beta-prop_EML_2 13 fvTagdDktvrlWdlekkklvakvklekearsv.afspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgs 100 ++ ++ D + + +++e+ k ++ +++++++s +s+ + +l vG+++G+++ +d+ t+++ + + + e s +pdg++ +gs FUN_000247-T1 958 VFFCSFDANCYAFNTESGKELWVFQTDSAIQSSpVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGHIF-IGS 1045 566999***********************9876156777889***************9999888887777777776667776543.455 PP == domain 4 score: 6.9 bits; conditional E-value: 0.0042 Beta-prop_EML_2 16 agdDktvrlWdlekkklvakvklekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiyl 107 ++ +++++ d ++ k+ ++ + + e+ s f + ++ +G+ +G+vl l++++++ v ++k+++ s + ++g +L +g d+++y FUN_000247-T1 1003 GSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGHIFIGSGEGEVLALRQTDGSLVWSFKTESAVWSSPRLGKNG-VLFIGGIDTYLYA 1093 5777889999999999999999999998888888888999*******************9999998888887777776.4566666776665 PP Beta-prop_EML_2 108 Y 108 FUN_000247-T1 1094 L 1094 4 PP >> Beta-prop_EMC1_N EMC1 N-terminal beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 6.7e-08 8.1e-05 33 216 .. 787 960 .. 775 970 .. 0.82 2 ? 5.1 0.1 0.014 17 92 147 .. 971 1024 .. 967 1031 .. 0.74 3 ! 6.1 0.2 0.0067 8.2 35 147 .. 1000 1106 .. 994 1113 .. 0.63 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 6.7e-08 Beta-prop_EMC1_N 33 krvlVaTeenviAslnlrtGeiaWRhvleedaegqidilLssgklvvtvsgggrllRaWnlpdGqlnWetslqssspskallvveedkdksvl 125 + ++++++ + i + ++ +G+ W+ eg +++++s+ vv + + lRa ++ +G+l+W+ s + +s++ + + d s+ FUN_000247-T1 787 STLYLSSDDHWIYAFDAVSGKMKWKYGT--ADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSST----RVGPDGSLY 873 5799********************9886..667777777789999************************99866666665....334555555 PP Beta-prop_EMC1_N 126 vl.kksaltalslsdGevkwkeelpeselviyqvlqspgsdkvyvvGvvesskvvvvqldaedGevlkqksvsapwlslsgecvlvssdvLv 216 + ++ +a++ dG++kwk++l e e++ ++ s+g k +G ++ +v +l+ +Ge+l +++++ p + +s ++++ ++v+ FUN_000247-T1 874 FGcLDGYFYAINP-DGSLKWKQNLGE-EIWSSPAVLSNG--KTLFIGSMADGAANVFALNCATGEILWDNETKGPVF-SSPTISYDGKTVFF 960 5447788888886.9*********97.599999999955..55889*************************999997.55555554455555 PP == domain 2 score: 5.1 bits; conditional E-value: 0.014 Beta-prop_EMC1_N 92 nlpdGqlnWetslqssspskallvveedkdksvlvl.kksaltalslsdGevkwkee 147 n+++G+ W + +s s+ vv ++ d +++v +++ ++a+++ +G+vkw++e FUN_000247-T1 971 NTESGKELWVFQTDSAIQSSP--VV-SKVDGTLFVGsSEGNIYAVDSATGKVKWTRE 1024 677777777666655555555..32.56778888876999**************987 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0067 Beta-prop_EMC1_N 35 vlVaTeenviAslnlrtGeiaWRhvleedaegqidilLssgklvvtv.sgggrllRaWnlpdGqlnWetslqssspskallvveedkdksv 124 ++V + e i ++++ tG++ W + + + ++ i+ + + sg+g++ a +dG+l+W +s s+ ++ v FUN_000247-T1 1000 LFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIA---PDGHIFIgSGEGEV-LALRQTDGSLVWSFKTESAVWSSP-----RLGKNGV 1081 5665555556678888888888765433333333333...34444440445554.466889999999877766666665.....3345555 PP Beta-prop_EMC1_N 125 lvl..kksaltalslsdGevkwkee 147 l++ ++ l+al ++dG+v+wk + FUN_000247-T1 1082 LFIggIDTYLYALRSEDGQVVWKYK 1106 5554778999999999999999876 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.1 3.6e-07 0.00043 58 258 .. 785 988 .. 755 991 .. 0.82 2 ! 17.8 0.0 1.5e-06 0.0018 61 174 .. 957 1071 .. 908 1092 .. 0.82 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 3.6e-07 Beta-prop_THOC3 58 hpdllatassDktvrlWdvrtgkstatvktkgen.inlawspdGktiavgskddtvslidvrtgkvkkeekfkkev.nevafspdgkllllttg 149 ++ +l +s+D+ + +d+ +gk + t +e ++a++ dG+++ +g++d+ ++ +d+ +g+ + + ++ + ++++ pdg+ l++++ FUN_000247-T1 785 RDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGgSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAItSSTRVGPDGS-LYFGCL 877 455778899***************9999997776268****************************9999888877615788889988.566999 PP Beta-prop_THOC3 150 dgtvevlsypsleevktlkahtsnclcvafdpkgrylAvGs.aDalvslWDleeliclrtl.trlespvrsv.sFShdGkllAsasedktidia 240 dg + ++ p++ ++ + ++ + a+ +g++l +Gs aD +++ l+ + + ++++ pv s +S+dGk++ +s d++ + FUN_000247-T1 878 DGYFYAIN-PDGSLKWKQNLGEEIWSSPAVLSNGKTLFIGSmADGAANVFALNCATGEILWdNETKGPVFSSpTISYDGKTVFFCSFDANCYAF 970 99998887.7777777777777778888888999999999967*********9776554441568888865427******************** PP Beta-prop_THOC3 241 svetgesvhtikteaavn 258 ++e+g++++ ++t++a++ FUN_000247-T1 971 NTESGKELWVFQTDSAIQ 988 ************999876 PP == domain 2 score: 17.8 bits; conditional E-value: 1.5e-06 Beta-prop_THOC3 61 llatassDktvrlWdvrtgkstatvktkgenin..lawspdGktiavgskddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgd 150 ++ +s D + +++++gk++ ++t++ + + + dG t+ vgs++ ++ +d tgkvk +++ k e + f ++++++g+ FUN_000247-T1 957 TVFFCSFDANCYAFNTESGKELWVFQTDSAIQSspVVSKVDG-TLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGHIFIGSGE 1047 4556888999999**************998865446666676.899*********************************99999999***** PP Beta-prop_THOC3 151 gtvevlsypsleevktlkahtsnc 174 g+v l+ +++ v+++k ++ FUN_000247-T1 1048 GEVLALRQTDGSLVWSFKTESAVW 1071 ************999999877655 PP >> JmjC_2 JmjC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.4 0.0 1.1e-09 1.3e-06 14 118 .. 265 381 .. 252 390 .. 0.65 Alignments for each domain: == domain 1 score: 28.4 bits; conditional E-value: 1.1e-09 JmjC_2 14 lddllisfslvgsnvYatpggsegvgpHyDeydvfilQleGkkrWrvgk..............pkeeeqeekseeelklldef..epvedlvLepG 93 ++++ + s + +g+++ H+D y+ ++ + G+k v + + e+ + + +l+++ + p + +vL++G FUN_000247-T1 265 CEEVMNTI---ASTHLLFSSGNTSSSCHMDGYENLLSVIAGTKEILVADpkyieyfyprnhttVNIESPIDPEAVDLEKFPKLaeIPFHKVVLKAG 357 44555555...444445556668889999999999999999999999888888888776643211111112222233333333445789******* PP JmjC_2 94 DlLYlPrgliHqgvaeeesltlsvg 118 D+LY+P++++H+ ++ + + +++++ FUN_000247-T1 358 DILYIPQHWWHHVRSYN-CPNIAIS 381 ************99987.5444444 PP >> Beta-prop_CGLA Lambda-carrageenase beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.1 0.023 28 51 108 .. 793 850 .. 783 866 .. 0.80 2 ? 1.6 0.0 0.18 2.2e+02 53 87 .. 878 912 .. 872 919 .. 0.76 3 ! 11.2 0.2 0.00021 0.25 11 107 .. 925 1018 .. 913 1032 .. 0.75 4 ! 13.1 0.1 5.8e-05 0.071 5 109 .. 1004 1102 .. 1000 1109 .. 0.73 5 ? 2.6 0.0 0.089 1.1e+02 49 75 .. 1084 1110 .. 1075 1120 .. 0.76 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.023 Beta-prop_CGLA 51 nadGslyclds.kGkllWkfkkneaPmyavcvvkkekkpYvvcGgfDkniyyLsa.kGel 108 + d +y+ d+ +Gk+ Wk+ + + + c+ ++++ + v cG Dk++ L+a +G+l FUN_000247-T1 793 SDDHWIYAFDAvSGKMKWKYGTADEG-GSKCAFNSDG-TVVYCGTDDKSLRALDAvSGSL 850 5567799999659********99876.6778888776.5799*********998735665 PP == domain 2 score: 1.6 bits; conditional E-value: 0.18 Beta-prop_CGLA 53 dGslycldskGkllWkfkkneaPmyavcvvkkekk 87 dG y+++ +G+l Wk + e + +v++++k+ FUN_000247-T1 878 DGYFYAINPDGSLKWKQNLGEEIWSSPAVLSNGKT 912 99999999999999998777666666666665555 PP == domain 3 score: 11.2 bits; conditional E-value: 0.00021 Beta-prop_CGLA 11 vlavsy.dGkilWknklsGfmnhdiwceDitgDgkdEilaanadGslycld.skGkllWkfkkneaPmyavcvvkk.ekkpYvvcGgfDkniy 100 v+a++ +G+ilW+n+ G + i Dgk ++ + d + y+ + ++Gk+lW f++ +a + + vv+k +++ +v G+ + niy FUN_000247-T1 925 VFALNCaTGEILWDNETKGPVFS---SPTISYDGKT-VFFCSFDANCYAFNtESGKELWVFQTDSA-IQSSPVVSKvDGTLFV--GSSEGNIY 1010 66666426999999999998754...4679999985.9999**********558*******99855.6666666662556554..99999999 PP Beta-prop_CGLA 101 yLsa.kGe 107 +++ +G+ FUN_000247-T1 1011 AVDSaTGK 1018 98651454 PP == domain 4 score: 13.1 bits; conditional E-value: 5.8e-05 Beta-prop_CGLA 5 ssYeGtvlavsy.dGkilWknklsGfmnhdiwceDitgDgkdEilaanadGslyclds.kGkllWkfkkneaPmyavcvvkkekkpYvvcGgf 95 s eG + av+ +Gk++W+ + G + i Dg+ i++ + +G++ +l + +G+l+W+fk+++a + + +k+ + Gg+ FUN_000247-T1 1004 S-SEGNIYAVDSaTGKVKWTREGKGELFSSPF---IAPDGH--IFIGSGEGEVLALRQtDGSLVWSFKTESAVWSS-PRL--GKNGVLFIGGI 1087 4.489999987526999999998886655544...567775..*************8549*********9654333.333..45556778*** PP Beta-prop_CGLA 96 DkniyyLsa.kGelv 109 D+ +y L + +G++v FUN_000247-T1 1088 DTYLYALRSeDGQVV 1102 *****9965167766 PP == domain 5 score: 2.6 bits; conditional E-value: 0.089 Beta-prop_CGLA 49 aanadGslyclds.kGkllWkfkkneaP 75 + d ly+l s +G+++Wk+k+ P FUN_000247-T1 1084 IGGIDTYLYALRSeDGQVVWKYKTD-GP 1110 5667899****8538*******986.44 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.1 2.1e-05 0.026 21 130 .. 789 856 .. 772 887 .. 0.62 2 ! 7.9 0.0 0.0019 2.3 135 214 .. 946 1024 .. 897 1072 .. 0.53 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 2.1e-05 Beta-prop_WDR5 21 lasasaDktikiwdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSGsfDetvr 115 l +s D+ i +d+ +gk++ + +G s+ a++sd++++ ++ DDk++r d+ +g+l+ FUN_000247-T1 789 LYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLI-------------------------------- 851 344556666666666666666666666666666666666666666666666666665555554................................ PP Beta-prop_WDR5 116 lWdvrtgkclktlpa 130 ++ FUN_000247-T1 852 ----------WKFST 856 ..........44444 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0019 Beta-prop_WDR5 135 vsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvsfvkFspngkyiLastldstirLwdyekekvvktYk 214 s+ +++dg+++ +s+D + ++te+g+ l + +d+ + + s + + + + + +i +d +++kv+ t + FUN_000247-T1 946 FSSPTISYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSAIQS-SPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTRE 1024 34445556666666666666666666666666655543332222.22233333344444444445445544444444333 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 3.2e-05 0.039 67 207 .. 788 927 .. 785 932 .. 0.76 2 ! 7.9 0.0 0.0016 2 26 147 .. 918 1037 .. 908 1062 .. 0.69 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 3.2e-05 WDR55 67 klfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtlt 162 +l+ s D+ i ++d+ +gk+k+k+ +a+e ++ d +++ G dd ++ D + + +++++ + s+ v + L + dG++ FUN_000247-T1 788 TLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRVGP-DGSLYFGCLDGYFY 882 678888899999999999999999999999999999999999999999999999999999999999887766555555554.55678888888888 PP WDR55 163 vfnirkkklevqseeyeeellslalvkeekkvvvGs.seGklylfn 207 ++n +l+ + + ee s a++ ++k + +Gs +G+ ++f FUN_000247-T1 883 AINPD-GSLKWKQNLGEEIWSSPAVLSNGKTLFIGSmADGAANVFA 927 88865.5566666777777777778888888877763467777775 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0016 WDR55 26 tidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllvid..enllatGdddG 117 + dG ++ ++ ++e l+ e++ + + s dGk++f +s D ++ ++++e+gk ++ +++ s+i+s v++ + +l+ G +G FUN_000247-T1 918 MADGAANVFALNCATGE--ILWDNETKGPVFSSPTISYDGKTVFFCSFDANCYAFNTESGKELWVFQTD--SAIQSSPVVSkvDGTLFVGSSEG 1007 55788888888886664..6788888888888888999****************999999988888744..44444433331144667788889 PP WDR55 118 tvklWDlRkkkavmelkehedyisdlvvde 147 ++ D + k ++ + + s+ + FUN_000247-T1 1008 NIYAVDSATGKVKWTREGKGELFSSPFIAP 1037 988888777776666666666666655555 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.6 0.1 0.00019 0.23 40 118 .. 785 862 .. 752 928 .. 0.75 2 ? 5.4 0.0 0.016 19 38 131 .. 952 1045 .. 918 1093 .. 0.62 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00019 Beta-prop_WDR3_1st 40 dgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvts 118 ++++l ++d +i +d+ sg+++ ++ + + af++dg+ + +G D+++ D v+++ +++++ +++ts FUN_000247-T1 785 RDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFST-GGAITS 862 4567888999******************************************************99999864.345555 PP == domain 2 score: 5.4 bits; conditional E-value: 0.016 Beta-prop_WDR3_1st 38 spdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvafleekk 126 s dgk++ + d + +++esg+ +f+ ++ ++ +k + +L+ Gs++ +i +D +++ ++ +g + s + ++++ FUN_000247-T1 952 SYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGH 1040 55566666666666666666666666666666665556666666666666666666666666666666555555444444444444444 PP Beta-prop_WDR3_1st 127 vlvss 131 + + s FUN_000247-T1 1041 IFIGS 1045 44444 PP >> SSL_N Strictosidine synthase-like, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 9.4 1.1e+04 31 45 .. 786 800 .. 781 801 .. 0.80 2 ! 6.5 0.1 0.0086 10 27 41 .. 865 879 .. 863 884 .. 0.88 3 ? 5.2 0.0 0.023 28 30 44 .. 996 1010 .. 992 1012 .. 0.87 4 ? 0.6 0.0 0.61 7.4e+02 28 44 .. 1035 1051 .. 1034 1053 .. 0.89 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 9.4 SSL_N 31 dGrlYtgladGrIvR 45 d +lY +++d +I+ FUN_000247-T1 786 DSTLYLSSDDHWIYA 800 6789*9999988875 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0086 SSL_N 27 avdadGrlYtgladG 41 v++dG lY+g +dG FUN_000247-T1 865 RVGPDGSLYFGCLDG 879 589***********9 PP == domain 3 score: 5.2 bits; conditional E-value: 0.023 SSL_N 30 adGrlYtgladGrIv 44 dG+l++g+ +G+I+ FUN_000247-T1 996 VDGTLFVGSSEGNIY 1010 59************9 PP == domain 4 score: 0.6 bits; conditional E-value: 0.61 SSL_N 28 vdadGrlYtgladGrIv 44 + +dG ++ g+ +G+++ FUN_000247-T1 1035 IAPDGHIFIGSGEGEVL 1051 579***********998 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.0033 4 30 81 .. 810 859 .. 791 864 .. 0.81 2 ? -1.5 0.0 3.7 4.5e+03 48 81 .. 953 986 .. 924 997 .. 0.81 3 ? 1.0 0.0 0.58 7.1e+02 48 72 .. 996 1019 .. 973 1029 .. 0.75 4 ? 1.9 0.0 0.3 3.7e+02 13 78 .. 1044 1107 .. 1037 1113 .. 0.73 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0033 ANAPC4_WD40 30 wklseekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksd 81 wk d+ ++ a++ dG++ +++d ++r ld+ sg l+ ++s++ FUN_000247-T1 810 WKY--GTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGA 859 555..34444446789******************************998765 PP == domain 2 score: -1.5 bits; conditional E-value: 3.7 ANAPC4_WD40 48 pdGklLavaysdgevrlldvesgklvhslsaksd 81 dGk + d ++ ++ esgk + +++ s FUN_000247-T1 953 YDGKTVFFCSFDANCYAFNTESGKELWVFQTDSA 986 5788888888899999999999999988887765 PP == domain 3 score: 1.0 bits; conditional E-value: 0.58 ANAPC4_WD40 48 pdGklLavaysdgevrlldvesgkl 72 dG L v+ s+g++ +d+ +gk+ FUN_000247-T1 996 VDG-TLFVGSSEGNIYAVDSATGKV 1019 455.477999***********9997 PP == domain 4 score: 1.9 bits; conditional E-value: 0.3 ANAPC4_WD40 13 atedgevllkRl.nwqrvwklseekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsa 78 ++ +gevl+ R ++ vw++ k++s+v s + +L ++ d+ + l +e+g++v ++++ FUN_000247-T1 1044 GSGEGEVLALRQtDGSLVWSF---KTESAVWSSPRLGKNGVLFIGGIDTYLYALRSEDGQVVWKYKT 1107 566677777665488889998...6666666655555666888888888888888899888887766 PP >> JmjC JmjC domain, hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.1 1.8e-05 0.022 76 105 .. 345 374 .. 321 384 .. 0.85 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.8e-05 JmjC 76 egipvyrivqkpgefVivfpgayHavfnlg 105 ++ip++++v k+g++++++ ++H v ++ FUN_000247-T1 345 AEIPFHKVVLKAGDILYIPQHWWHHVRSYN 374 67************************9875 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.073 89 55 224 .. 820 860 .. 768 886 .. 0.66 2 ? 8.9 0.0 0.00093 1.1 54 126 .. 946 1020 .. 921 1068 .. 0.56 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.073 WD40_CDC20-Fz 55 tsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalawnenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrll 150 + +++++dg+++ +Gt++ +++ +d+ +++ + ++++ FUN_000247-T1 820 SKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTG---------------------------------------------------------- 857 55666666666666666666666666666555554443.......................................................... PP WD40_CDC20-Fz 151 AsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgsqv 224 + FUN_000247-T1 858 -----------------------------------------------------------------------GAI 860 .......................................................................333 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00093 WD40_CDC20-Fz 54 vtsvkwsedgelLavGtssgevelwdvekkkklrtleghs..srvgalawnenllssGsrdgkilhhDvrtkele 126 +s s dg+++ + + + +++ +++e++k+l ++++s ++ +++ + +l++Gs++g+i+ D t +++ FUN_000247-T1 946 FSSPTISYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSaiQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVK 1020 555555555555555555555555555555555444433211334444444455555555555555555544433 PP >> Cupin_2 Cupin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 0.00026 0.31 37 57 .. 351 371 .. 349 374 .. 0.92 2 ? -2.5 0.0 5.1 6.2e+03 14 38 .. 720 745 .. 715 746 .. 0.76 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00026 Cupin_2 37 evvlkaGdsvyfpagvpHrfr 57 +vvlkaGd++y+p + +H++r FUN_000247-T1 351 KVVLKAGDILYIPQHWWHHVR 371 799****************97 PP == domain 2 score: -2.5 bits; conditional E-value: 5.1 Cupin_2 14 hrHpge.effyVleGeleltvdgeev 38 h ++ e+f l+G++++ dg ++ FUN_000247-T1 720 HLNNHDrEYFKNLDGKIVVPDDGPPY 745 555555799999****9998888776 PP >> SUKH-4 SUKH-4 immunity protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.97 1.2e+03 79 110 .. 910 944 .. 889 950 .. 0.77 2 ? 8.0 0.0 0.0033 4.1 67 111 .. 985 1029 .. 964 1037 .. 0.83 3 ? -1.2 0.0 2.2 2.7e+03 79 105 .. 1038 1065 .. 1034 1074 .. 0.76 4 ? -0.6 0.0 1.4 1.7e+03 63 110 .. 1062 1110 .. 1048 1117 .. 0.77 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.97 SUKH-4 79 esllvLGal...egaslvldpatGaVlavsleade 110 ++ l +G++ ++++l+ atG++l+ +++++ FUN_000247-T1 910 GKTLFIGSMadgAANVFALNCATGEILWDNETKGP 944 5677889998888999***********98777766 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0033 SUKH-4 67 aaersaelpadaesllvLGalegaslvldpatGaVlavsleader 111 a +s ++ +++++ l +G+ eg+ +++d atG+V + +++++e+ FUN_000247-T1 985 SAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGEL 1029 455667777899999**********************99999876 PP == domain 3 score: -1.2 bits; conditional E-value: 2.2 SUKH-4 79 esllvLGalegaslvldpatGa.Vlavs 105 ++ + +G+ eg +l+l++++G+ V+ ++ FUN_000247-T1 1038 DGHIFIGSGEGEVLALRQTDGSlVWSFK 1065 6778899999999999999998344444 PP == domain 4 score: -0.6 bits; conditional E-value: 1.4 SUKH-4 63 lalvaaersaelpa.daesllvLGalegaslvldpatGaVlavsleade 110 +++ +++ + +p+ + ++l +G ++ ++l+ ++G+V++ +++++ FUN_000247-T1 1062 WSFKTESAVWSSPRlGKNGVLFIGGIDTYLYALRSEDGQVVWKYKTDGP 1110 5556666666666546778999******************997777766 PP >> DUF7957 Domain of unknown function (DUF7957) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00026 0.32 49 106 .. 965 1020 .. 962 1024 .. 0.80 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00026 DUF7957 49 rNviafdk.dGnklWeieelpeekeskpyveiavedgeLiasswnsyeykiDietGeve 106 N af++ G++lW + ++ +s+p +++ dg L ++s +++ y +D +tG+v+ FUN_000247-T1 965 ANCYAFNTeSGKELWVFQ-TDSAIQSSP--VVSKVDGTLFVGSSEGNIYAVDSATGKVK 1020 5888887526999**999.555555555..456789*********************97 PP >> PD40 WD40-like Beta Propeller Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 7.9 9.6e+03 14 25 .. 864 874 .. 856 874 .. 0.73 2 ? -1.7 0.0 3.7 4.5e+03 13 32 .. 903 921 .. 902 926 .. 0.74 3 ? 8.1 0.4 0.0031 3.8 13 28 .. 948 963 .. 946 972 .. 0.93 4 ? 1.8 0.0 0.29 3.6e+02 13 26 .. 1032 1045 .. 1026 1059 .. 0.82 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 7.9 PD40 14 PsfSPDGkrlaF 25 ++ PDG +l+F FUN_000247-T1 864 TRVGPDG-SLYF 874 56669**.8888 PP == domain 2 score: -1.7 bits; conditional E-value: 3.7 PD40 13 ePsfSPDGkrlaFsSdrdsG 32 +P++ ++Gk+l S d G FUN_000247-T1 903 SPAVLSNGKTLFIGSMAD-G 921 69999*****98766555.5 PP == domain 3 score: 8.1 bits; conditional E-value: 0.0031 PD40 13 ePsfSPDGkrlaFsSd 28 +P++S DGk+ F+S+ FUN_000247-T1 948 SPTISYDGKTVFFCSF 963 7**************8 PP == domain 4 score: 1.8 bits; conditional E-value: 0.29 PD40 13 ePsfSPDGkrlaFs 26 +P++ PDG ++ s FUN_000247-T1 1032 SPFIAPDGHIFIGS 1045 8*******777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 913 (0.0357408); expected 510.9 (0.02) Passed bias filter: 700 (0.0274026); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 21 [number of targets reported over threshold] # CPU time: 0.52u 0.40s 00:00:00.92 Elapsed: 00:00:00.43 # Mc/sec: 10469.70 // Query: FUN_000247-T2 [L=1083] Description: FUN_000247 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-65 220.4 0.1 6.5e-34 118.3 0.0 2.2 2 Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-prop 5.5e-50 170.7 5.8 1e-20 74.9 0.0 3.8 4 PQQ_2 Outer membrane protein assembly factor Ba 5.7e-47 160.7 0.0 1.1e-46 159.8 0.0 1.4 1 Aldo_ket_red Aldo/keto reductase family 1e-36 127.6 1.8 1.9e-36 126.7 1.8 1.4 1 Cupin_8 Cupin-like domain 2.8e-19 69.7 0.3 2.1e-05 23.9 0.0 6.1 6 PQQ Glucose/ethanol/alcohol dehydrogenase, be 4.3e-09 36.6 0.0 0.00066 19.6 0.0 3.2 5 Beta-prop_EML_2 Echinoderm microtubule-associated protein 8.4e-09 35.7 0.1 7.7e-05 22.7 0.0 3.3 3 Beta-prop_EMC1_N EMC1 N-terminal beta-propeller domain 1.8e-08 34.2 0.0 0.00039 20.0 0.1 2.4 2 Beta-prop_THOC3 THOC3 beta-propeller domain 4.4e-07 30.2 5.6 0.067 13.1 0.1 4.7 5 Beta-prop_CGLA Lambda-carrageenase beta-propeller domain 1.3e-06 28.5 0.0 6.4e-06 26.2 0.0 2.2 1 JmjC_2 JmjC domain 2e-05 24.5 0.3 0.025 14.4 0.1 2.2 2 Beta-prop_WDR5 WDR5 beta-propeller domain 3.4e-05 23.5 0.0 0.035 13.6 0.0 2.8 3 WDR55 WDR55 0.00097 19.4 0.3 0.22 11.7 0.1 2.5 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 0.0038 17.5 0.5 10 6.6 0.1 4.0 4 SSL_N Strictosidine synthase-like, N-terminal 0.0039 17.9 0.1 3.8 8.3 0.0 4.2 4 ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 ------ inclusion threshold ------ 0.011 15.8 0.0 0.023 14.8 0.0 1.4 1 Cupin_1 Cupin 0.018 14.9 0.1 1.1 9.0 0.0 2.6 3 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 0.036 14.3 0.1 0.21 11.8 0.1 2.3 2 Cupin_2 Cupin domain 0.036 15.0 0.4 0.11 13.5 0.1 2.0 1 JmjC JmjC domain, hydroxylase 0.054 14.1 0.0 4 8.0 0.0 3.5 3 SUKH-4 SUKH-4 immunity protein 0.068 13.9 0.3 0.3 11.8 0.0 2.3 1 DUF7957 Domain of unknown function (DUF7957) 1.4 9.4 6.7 3.7 8.1 0.4 4.0 4 PD40 WD40-like Beta Propeller Repeat 8.2 7.7 7.3 3.4 8.9 0.2 4.2 2 WD40 WD domain, G-beta repeat Domain annotation for each model (and alignments): >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.2 0.0 5.4e-33 6e-30 11 192 .. 734 918 .. 730 919 .. 0.87 2 ! 118.3 0.0 5.8e-37 6.5e-34 57 225 .. 907 1076 .. 906 1081 .. 0.94 Alignments for each domain: == domain 1 score: 105.2 bits; conditional E-value: 5.4e-33 Beta-prop_ACSF4 11 vvaktvdksselvvvgSHsgkivcvdletgeviweielpdriEssacvskdgklvvvGcydgklycldlatgeilwkfktgdaiKsspvidses 104 v++++vd +++++ S ++ i ++d+ +g++ w++ d+ s++++++dg+ v+ G+ d++l +ld+ +g+++wkf+tg+ai ss + + FUN_000247-T2 734 VLIERVDLRDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRVGP-D 826 5556677788899999999**************************99999**********************************99999976.5 PP Beta-prop_ACSF4 105 glvvvgsydknlyaldvesgklvwklklggsifsspllskskesvlvatldG...tvaalseesgeilWkvklesPiFsspvilsde..vvva 192 g++++g+ d+++ya++ + g+l+wk +lg++i ssp++ ++ +++++++++ +v+al+ ++geilW +++ P+Fssp+i+ d v+++ FUN_000247-T2 827 GSLYFGCLDGYFYAINPD-GSLKWKQNLGEEIWSSPAVLSNGKTLFIGSMADgaaNVFALNCATGEILWDNETKGPVFSSPTISYDGktVFFC 918 6889***********995.9****************999999999999985323378999999******************998653225555 PP == domain 2 score: 118.3 bits; conditional E-value: 5.8e-37 Beta-prop_ACSF4 57 cvskdgklvvvGcydgklycldlatgeilwkfktgdaiKsspvidsesglvvvgsydknlyaldvesgklvwklklggsifsspllskskes 148 ++s dgk v++ ++d + y+++ ++g+ lw f+t++ai sspv+ + g+++vgs ++n+ya+d +gk++w+++ +g++fssp + + + FUN_000247-T2 907 TISYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIA-PDGH 997 68999*********************************************************************************5.6899 PP Beta-prop_ACSF4 149 vlvatldGtvaalseesgeilWkvklesPiFsspvilsde.vvvaevdgtvlcls.eegeklwsvktkgpiFsspvlvk 225 +++++ +G+v+al +++g+++W++k+es + ssp + ++ ++++ +d +++l+ e+g+ +w++kt+gp+ +p++ + FUN_000247-T2 998 IFIGSGEGEVLALRQTDGSLVWSFKTESAVWSSPRLGKNGvLFIGGIDTYLYALRsEDGQVVWKYKTDGPVVGTPLITR 1076 ************************************87753789**********8578**************9999864 PP >> PQQ_2 Outer membrane protein assembly factor BamB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 0.0 1.1e-09 1.3e-06 32 129 .. 742 837 .. 730 843 .. 0.75 2 ! 74.9 0.0 9.4e-24 1e-20 3 177 .. 836 1003 .. 834 1005 .. 0.80 3 ! 54.4 0.4 1.7e-17 1.9e-14 6 102 .. 925 1024 .. 925 1032 .. 0.90 4 ! 39.4 0.2 6.5e-13 7.2e-10 2 77 .. 1004 1080 .. 1003 1083 .] 0.89 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 1.1e-09 PQQ_2 32 dggrlfvasgggelvaldaetGkllWrqalsgevlga.Plvaggrv.vvvaadgtlialdakdGrrlWslqrseealalrsssspavvgdtvvlgf 125 +++l+ s+ ++a+da +Gk W++ e ++ ++++g+v ++ ++d++l+alda +G++ W + ++ + ++ss+++ ++ +++g+ FUN_000247-T2 742 RDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKcAFNSDGTVvYCGTDDKSLRALDAVSGSLIWKFSTG----GAITSSTRVGPDGSLYFGC 833 57899***********************99555555545666666659999999***************7777....3334444444455555555 PP PQQ_2 126 ssgk 129 +g FUN_000247-T2 834 LDGY 837 5555 PP == domain 2 score: 74.9 bits; conditional E-value: 9.4e-24 PQQ_2 3 gtvaaldaatGaelWrvdlerk.lgggvav.dggrlfva...sgggelvaldaetGkllWrqalsgevlgaPlv..aggrvvvvaadgtliald 89 g +a+++ +G++ W+++l+++ +++ ++ +g++lf++ +g + + al+ +tG++lW ++ +g+v ++P++ +g++v+ + d +a++ FUN_000247-T2 836 GYFYAINP-DGSLKWKQNLGEEiWSSPAVLsNGKTLFIGsmaDGAANVFALNCATGEILWDNETKGPVFSSPTIsyDGKTVFFCSFDANCYAFN 928 56679997.8*********655155555667999****9666699**************************9973368899************* PP PQQ_2 90 akdGrrlWslqrseealalrsssspavvgdtvvlgfssgklvaldpktGkvlweasvaaprgtseiervgdvtgrpvva.ggrVyassg 177 +++G++lW +q+ a+ ss+ v++t+++g s g+++a+d +tGkv w ++ g+++++p++a +g +++ sg FUN_000247-T2 929 TESGKELWVFQTD---SAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREG-----K------GELFSSPFIApDGHIFIGSG 1003 *********7766...3555666666679************************9832.....2......23466666663346666665 PP == domain 3 score: 54.4 bits; conditional E-value: 1.7e-17 PQQ_2 6 aaldaatGaelWrvdlerklgggv.av.dggrlfvasgggelvaldaetGkllWrqalsgevlgaPlva.ggrvvvvaadgtlialdakdGrrl 96 +a++ ++G+elW ++ ++++ + ++ +g+lfv+s +g ++a+d +tGk+ W+ + +ge+ ++P++a +g++++ +++g++ al ++dG+++ FUN_000247-T2 925 YAFNTESGKELWVFQTDSAIQSSPvVSkVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIApDGHIFIGSGEGEVLALRQTDGSLV 1018 58999*********88667777775889**************************************99878999******************** PP PQQ_2 97 Wslqrs 102 Ws++++ FUN_000247-T2 1019 WSFKTE 1024 **5544 PP == domain 4 score: 39.4 bits; conditional E-value: 6.5e-13 PQQ_2 2 dgtvaaldaatGaelWrvdlerk.lgggvavdggrlfvasgggelvaldaetGkllWrqalsgevlgaPlvaggrvv 77 +g+v al +++G+++W+++ e + +++ + ++g+lf+++ l+al e+G ++W+++ +g+v+g+Pl+++++ v FUN_000247-T2 1004 EGEVLALRQTDGSLVWSFKTESAvWSSPRLGKNGVLFIGGIDTYLYALRSEDGQVVWKYKTDGPVVGTPLITREHAV 1080 799***************9966516666667****************************************999875 PP >> Aldo_ket_red Aldo/keto reductase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.8 0.0 9.5e-50 1.1e-46 1 286 [. 426 687 .. 426 690 .. 0.94 Alignments for each domain: == domain 1 score: 159.8 bits; conditional E-value: 9.5e-50 Aldo_ket_red 1 klglGtwqlgggegrvskeealetlkaaldaGirfiDtAevYgdgksEellgealkksrvkrekvfiatKvkgdgpwksglskeeirksleeslkr 96 klg+Gt+ l+ e+ + + al aG+r+iD+A++Y +Ee +g al+ks +re++fi++Kv ++ l ++e +s+eeslk+ FUN_000247-T2 426 KLGFGTAGLF--------EDTKSSVLLALNAGYRLIDSAQAY----NEEHVGFALEKSGIPREDIFIVSKV-----HPRFLGYQETLQSVEESLKN 504 5788888888........788889999***************....*************************.....999999************** PP Aldo_ket_red 97 lgtdylDllylHwpdpstp...............ieetlkaLeelkkeGkiraiGvSnfdieqiekakkkkkipivavqveynllrrreeeellel 177 l+++y+Dl ++H d++ e+ +kaLe l+ + kir+iGvSnf++++++++++ + i +++vq+++ ++ ++++e +e+ FUN_000247-T2 505 LKVSYIDLMLIHSMDCDEGpgahltcakgepkgtWEDSWKALESLVGKNKIRSIGVSNFEVKDLQRLLEIANIHPSVVQNSFDPF--NQDRETREF 598 ******************99*****************************************************************..********* PP Aldo_ket_red 178 cekkgigliaysplagGlltkkktkdedkgskeeredlkktslnlealealeelakehgvslaevalryalkkpkvtvvivgvsnleqleenlaal 273 c+k++i+++a+s+l+ + + ++ ++++ + +e l+++a++ + s+ ++++++ l ++ i+ ++n++++e n+ FUN_000247-T2 599 CKKNNIQFMAHSTLGDSWKR----EGLPQNP-------------VLSDEGLRKIATQFDASVPQLVIKWCL---EQAICIPRSRNPNHIETNFHLS 674 ***************66655....5555544.............4899***********************...899******************* PP Aldo_ket_red 274 efelsdeevarid 286 ++ l+ + ++++ FUN_000247-T2 675 HVHLNNHDREYFK 687 9999988776665 PP >> Cupin_8 Cupin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 126.7 1.8 1.8e-39 1.9e-36 4 249 .. 126 345 .. 124 347 .. 0.88 Alignments for each domain: == domain 1 score: 126.7 bits; conditional E-value: 1.8e-39 Cupin_8 4 ffreyvaknkPvvikgavkdwpavekwkdkeelldylkekagdvkvsveetpdgradalfenddltfvnpkeeemtfkeflkeleaesdqkaekal 99 f++ ++ k++P+v++ga+++w a++ w++ y+k+k+g+v++ ve t+ ++ p +++m+++++l+ ++++ + FUN_000247-T2 126 FYSHFIRKSQPLVMRGAASEWGAFKYWTN----DTYMKKKYGHVMFDVEFTK-------H----YEGIHPVKKTMNLSAYLDIYKTQ-------HV 199 77899***********************9....7999**********96666.......2....3467999***************9.......48 PP Cupin_8 100 ylqsaslrsefpelkedndlplateafg..eepkavnlWiGnersvtslHkDhyeNlycvvrGrKrFtLfpPsdvenLyegpleepegqsvslvdv 193 yl+ +++ + ++l++d +p + ++ + + +v+l + +++++slH+D y+Nl++v++G K++++ + +e+Ly + ++ s v++ FUN_000247-T2 200 YLD-SPFPQ--SDLTSDVMIPYCLQCEEvmSTITSVHLLYSSGNTSSSLHNDGYQNLLAVISGSKEVLVANSDNAEYLYANNY--TTIPGLSPVNP 290 998.44444..57888988886665544224588*********************************************9985..45779****** PP Cupin_8 194 dapdlekfprfreaakalevelepGdvLylPalWfHhVesldplniavnyWydmsf 249 +++dl+kfp ++++ + ++v l++Gd+Ly+P+ W+HhV+s++ nia+ W++++ FUN_000247-T2 291 ESVDLKKFPNVSKV-SFHKVVLKAGDILYIPQHWWHHVRSYNCPNIAISLWFHPFA 345 **************.**************************767********9976 PP >> PQQ Glucose/ethanol/alcohol dehydrogenase, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 1.9e-08 2.1e-05 57 153 .. 743 824 .. 717 833 .. 0.83 2 ! 6.8 0.0 0.0028 3.1 534 584 .. 853 906 .. 842 913 .. 0.71 3 ! 7.0 0.0 0.0025 2.8 57 579 .. 912 943 .. 904 950 .. 0.62 4 ! 16.0 0.0 4.7e-06 0.0052 47 86 .. 942 983 .. 939 990 .. 0.84 5 ? 2.7 0.0 0.05 56 55 87 .. 993 1025 .. 982 1032 .. 0.81 6 ! 7.8 0.0 0.0014 1.6 538 585 .. 1027 1073 .. 1020 1080 .. 0.84 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 1.9e-08 PQQ 57 dgvLylctptnrvvAldaatGeekWrfdpkvkekkslekltcRGvayweakaktaecakriilatadarLialdaatGkpcegFGekGvvdlkegl 152 d +Lyl++ +++++A da +G+ kW++ + + +c a+ ++ + ++ +t d+ L alda +G+++ +F ++G++ ++++ FUN_000247-T2 743 DSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGG-----SKC---AFNSD-------GTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRV 823 789************************8744322.....222...33333.......478999**************************9877766 PP PQQ 153 g 153 g FUN_000247-T2 824 G 824 5 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0028 PQQ 534 tgtpnlggpl.vtagglvfigatade..rlrAfdkktGeelwetelpagaqatp 584 +g+ +p + +g+ +fig++ad + A++ +tGe lw+ e + ++p FUN_000247-T2 853 LGEEIWSSPAvLSNGKTLFIGSMADGaaNVFALNCATGEILWDNETKGPVFSSP 906 555555555404567889999998853388999999999999998887777766 PP == domain 3 score: 7.0 bits; conditional E-value: 0.0025 PQQ 57 dgvLylctptnrvvAldaatGeekWrfdpkvkekkslekltcRGvayweakaktaecakriilatadarLialdaatGkpcegFGekGvvdlkegl 152 + ++++c+ + + +A + ++G+e+W+f+++ FUN_000247-T2 912 GKTVFFCSFDANCYAFNTESGKELWVFQTDS----------------------------------------------------------------- 942 4566667777777777777777777766554................................................................. PP PQQ 153 geaepgeygvtspPvvvgdtvvvggsvtdnqstkepsGvvrafDartGklkWafdpgeeeaeaepedeetytrgtanvWavlsaDeelglvYlptg 248 FUN_000247-T2 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 249 saspDfyGgdRkggdnlyasSvVALdaatGkvvWhfQtvhhDlwDyDlpaqPvLvditkdgkkipavaqvtKqgllFvldRetGeplfpveerpvp 344 FUN_000247-T2 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 345 qsdvpgeklspTQPfptlpalpaqdlteedlwgltpedqaacreklkklryeglftPpseqgtlvlPgalGgvnwggvaidpetgllivnsnelpa 440 FUN_000247-T2 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 441 vvklvpreeaealekkkeakgageesevkpqegtpyaverkpllsplglpcvkPPwgeltaidlntgeiaWqvplGttedsaplplkvklpletgt 536 FUN_000247-T2 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP PQQ 537 pnlggplvtagglvfigataderlrAfdkktGeelwetelpag 579 + FUN_000247-T2 943 ------------------------------------------A 943 ..........................................3 PP == domain 4 score: 16.0 bits; conditional E-value: 4.7e-06 PQQ 47 safeatPl..vvdgvLylctptnrvvAldaatGeekWrfdpk 86 sa++++P+ +vdg+L++ +++++++A+d atG+ kW+ + k FUN_000247-T2 942 SAIQSSPVvsKVDGTLFVGSSEGNIYAVDSATGKVKWTREGK 983 5677888733689************************98765 PP == domain 5 score: 2.7 bits; conditional E-value: 0.05 PQQ 55 vvdgvLylctptnrvvAldaatGeekWrfdpkv 87 + dg++++ +++++v+Al + G +W+f+++ FUN_000247-T2 993 APDGHIFIGSGEGEVLALRQTDGSLVWSFKTES 1025 458899999999999999999999999998765 PP == domain 6 score: 7.8 bits; conditional E-value: 0.0014 PQQ 538 nlggplvtagglvfigataderlrAfdkktGeelwetelpagaqatpm 585 +p + + g++fig+ d +l+A+ +++G+++w+++ + +tp FUN_000247-T2 1027 VWSSPRLGKNGVLFIGGI-DTYLYALRSEDGQVVWKYKTDGPVVGTPL 1073 55667778899****996.9******************9999999885 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 6e-07 0.00066 16 109 .. 749 842 .. 741 855 .. 0.88 2 ? 5.0 0.0 0.017 19 32 113 .. 847 932 .. 842 957 .. 0.78 3 ! 8.8 0.0 0.0012 1.4 13 73 .. 915 976 .. 870 985 .. 0.59 4 ! 10.6 0.0 0.00033 0.37 13 101 .. 915 1003 .. 907 1010 .. 0.81 5 ! 6.9 0.0 0.0044 4.9 16 108 .. 960 1051 .. 955 1069 .. 0.81 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 6e-07 Beta-prop_EML_2 16 agdDktvrlWdlekkklvakv.klekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylY 108 +dD+ ++ +d+ + k+ +k+ + ++ + +af++dg+++ +G++d s+ lda +++ + ++++ s + pdg+ L g+ d+++y FUN_000247-T2 749 SSDDHWIYAFDAVSGKMKWKYgTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRVGPDGS-LYFGCLDGYFYAI 841 69******************9555677788*************************************************8.5669999998866 PP Beta-prop_EML_2 109 d 109 + FUN_000247-T2 842 N 842 5 PP == domain 2 score: 5.0 bits; conditional E-value: 0.017 Beta-prop_EML_2 32 lvakvklekea.rsvafspdgkllavGlk.dG..svlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskk 113 l +k +l++e+ +s a+ ++gk+l +G+ dG +v+ l+ t+e + +++ s + s dgk++ +s d + y ++++++ FUN_000247-T2 847 LKWKQNLGEEIwSSPAVLSNGKTLFIGSMaDGaaNVFALNCATGEILWDNETKGPVFSSPTISYDGKTVFFCSFDANCYAFNTESG 932 5677888777647889999********843662256668889999999999999999*************************8754 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0012 Beta-prop_EML_2 13 fvTagdDktvrlWdlekkklvakvklekearsv.afspdgkllavGlkdGsvlvldaetlee 73 ++ ++ D + + +++e+ k ++ +++++++s +s+ + +l vG+++G+++ +d+ t+++ FUN_000247-T2 915 VFFCSFDANCYAFNTESGKELWVFQTDSAIQSSpVVSKVDGTLFVGSSEGNIYAVDSATGKV 976 33455566666666666666666666666554313444455566666666666666555544 PP == domain 4 score: 10.6 bits; conditional E-value: 0.00033 Beta-prop_EML_2 13 fvTagdDktvrlWdlekkklvakvklekearsv.afspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgsh 101 ++ ++ D + + +++e+ k ++ +++++++s +s+ + +l vG+++G+++ +d+ t+++ + + + e s +pdg++ +gs FUN_000247-T2 915 VFFCSFDANCYAFNTESGKELWVFQTDSAIQSSpVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGHIF-IGSG 1003 566999***********************9876156777889***************9999888887777777777777776543.4555 PP == domain 5 score: 6.9 bits; conditional E-value: 0.0044 Beta-prop_EML_2 16 agdDktvrlWdlekkklvakvklekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiyl 107 ++ +++++ d ++ k+ ++ + + e+ s f + ++ +G+ +G+vl l++++++ v ++k+++ s + ++g +L +g d+++y FUN_000247-T2 960 GSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGHIFIGSGEGEVLALRQTDGSLVWSFKTESAVWSSPRLGKNG-VLFIGGIDTYLYA 1050 5777889999999999999999999998888888888999*******************9999998888887777776.4566666776665 PP Beta-prop_EML_2 108 Y 108 FUN_000247-T2 1051 L 1051 4 PP >> Beta-prop_EMC1_N EMC1 N-terminal beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 6.9e-08 7.7e-05 33 216 .. 744 917 .. 732 927 .. 0.82 2 ? 5.3 0.1 0.014 15 92 147 .. 928 981 .. 924 990 .. 0.75 3 ! 6.0 0.2 0.008 8.9 36 147 .. 958 1063 .. 954 1070 .. 0.62 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 6.9e-08 Beta-prop_EMC1_N 33 krvlVaTeenviAslnlrtGeiaWRhvleedaegqidilLssgklvvtvsgggrllRaWnlpdGqlnWetslqssspskallvveedkdksvl 125 + ++++++ + i + ++ +G+ W+ eg +++++s+ vv + + lRa ++ +G+l+W+ s + +s++ + + d s+ FUN_000247-T2 744 STLYLSSDDHWIYAFDAVSGKMKWKYGT--ADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSST----RVGPDGSLY 830 5799********************9886..667777777789999************************99866666665....334555555 PP Beta-prop_EMC1_N 126 vl.kksaltalslsdGevkwkeelpeselviyqvlqspgsdkvyvvGvvesskvvvvqldaedGevlkqksvsapwlslsgecvlvssdvLv 216 + ++ +a++ dG++kwk++l e e++ ++ s+g k +G ++ +v +l+ +Ge+l +++++ p + +s ++++ ++v+ FUN_000247-T2 831 FGcLDGYFYAINP-DGSLKWKQNLGE-EIWSSPAVLSNG--KTLFIGSMADGAANVFALNCATGEILWDNETKGPVF-SSPTISYDGKTVFF 917 5447788888886.9*********97.599999999955..55889*************************999997.55555554455555 PP == domain 2 score: 5.3 bits; conditional E-value: 0.014 Beta-prop_EMC1_N 92 nlpdGqlnWetslqssspskallvveedkdksvlvl.kksaltalslsdGevkwkee 147 n+++G+ W + +s s+ vv ++ d +++v +++ ++a+++ +G+vkw++e FUN_000247-T2 928 NTESGKELWVFQTDSAIQSSP--VV-SKVDGTLFVGsSEGNIYAVDSATGKVKWTRE 981 677777777666655555555..32.56778888876999**************987 PP == domain 3 score: 6.0 bits; conditional E-value: 0.008 Beta-prop_EMC1_N 36 lVaTeenviAslnlrtGeiaWRhvleedaegqidilLssgklvvtv.sgggrllRaWnlpdGqlnWetslqssspskallvveedkdksvl 125 +V + e i ++++ tG++ W + + + ++ i+ + + sg+g++ a +dG+l+W +s s+ ++ vl FUN_000247-T2 958 FVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIA---PDGHIFIgSGEGEV-LALRQTDGSLVWSFKTESAVWSSP-----RLGKNGVL 1039 555555555668888888888665433333333333...33444440444554.466888999999877766666665.....33455555 PP Beta-prop_EMC1_N 126 vl..kksaltalslsdGevkwkee 147 ++ ++ l+al ++dG+v+wk + FUN_000247-T2 1040 FIggIDTYLYALRSEDGQVVWKYK 1063 554778999999999999999876 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 3.5e-07 0.00039 58 258 .. 742 945 .. 712 949 .. 0.82 2 ! 17.9 0.0 1.5e-06 0.0017 61 174 .. 914 1028 .. 865 1049 .. 0.82 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 3.5e-07 Beta-prop_THOC3 58 hpdllatassDktvrlWdvrtgkstatvktkgen.inlawspdGktiavgskddtvslidvrtgkvkkeekfkkev.nevafspdgkllllttg 149 ++ +l +s+D+ + +d+ +gk + t +e ++a++ dG+++ +g++d+ ++ +d+ +g+ + + ++ + ++++ pdg+ l++++ FUN_000247-T2 742 RDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGgSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAItSSTRVGPDGS-LYFGCL 834 455778899***************9999997776268****************************9999888877615788899988.566999 PP Beta-prop_THOC3 150 dgtvevlsypsleevktlkahtsnclcvafdpkgrylAvGs.aDalvslWDleeliclrtl.trlespvrsv.sFShdGkllAsasedktidia 240 dg + ++ p++ ++ + ++ + a+ +g++l +Gs aD +++ l+ + + ++++ pv s +S+dGk++ +s d++ + FUN_000247-T2 835 DGYFYAIN-PDGSLKWKQNLGEEIWSSPAVLSNGKTLFIGSmADGAANVFALNCATGEILWdNETKGPVFSSpTISYDGKTVFFCSFDANCYAF 927 99998887.7777777777777778888888999999999967*********9776554441568888865427******************** PP Beta-prop_THOC3 241 svetgesvhtikteaavn 258 ++e+g++++ ++t++a++ FUN_000247-T2 928 NTESGKELWVFQTDSAIQ 945 ************999876 PP == domain 2 score: 17.9 bits; conditional E-value: 1.5e-06 Beta-prop_THOC3 61 llatassDktvrlWdvrtgkstatvktkgenin..lawspdGktiavgskddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgd 150 ++ +s D + +++++gk++ ++t++ + + + dG t+ vgs++ ++ +d tgkvk +++ k e + f ++++++g+ FUN_000247-T2 914 TVFFCSFDANCYAFNTESGKELWVFQTDSAIQSspVVSKVDG-TLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGHIFIGSGE 1004 4556888999999**************998865446666676.899*********************************99999999***** PP Beta-prop_THOC3 151 gtvevlsypsleevktlkahtsnc 174 g+v l+ +++ v+++k ++ FUN_000247-T2 1005 GEVLALRQTDGSLVWSFKTESAVW 1028 ************999999877655 PP >> Beta-prop_CGLA Lambda-carrageenase beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 0.024 26 51 108 .. 750 807 .. 740 823 .. 0.80 2 ? 1.7 0.0 0.18 2e+02 53 87 .. 835 869 .. 829 879 .. 0.77 3 ! 11.3 0.2 0.00021 0.24 11 107 .. 882 975 .. 870 989 .. 0.75 4 ! 13.1 0.1 6e-05 0.067 5 109 .. 961 1059 .. 957 1066 .. 0.73 5 ? 2.6 0.0 0.094 1e+02 49 75 .. 1041 1067 .. 1032 1077 .. 0.76 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.024 Beta-prop_CGLA 51 nadGslyclds.kGkllWkfkkneaPmyavcvvkkekkpYvvcGgfDkniyyLsa.kGel 108 + d +y+ d+ +Gk+ Wk+ + + + c+ ++++ + v cG Dk++ L+a +G+l FUN_000247-T2 750 SDDHWIYAFDAvSGKMKWKYGTADEG-GSKCAFNSDG-TVVYCGTDDKSLRALDAvSGSL 807 5567799999659********99876.6778888776.5799*********998735666 PP == domain 2 score: 1.7 bits; conditional E-value: 0.18 Beta-prop_CGLA 53 dGslycldskGkllWkfkkneaPmyavcvvkkekk 87 dG y+++ +G+l Wk + e + +v++++k+ FUN_000247-T2 835 DGYFYAINPDGSLKWKQNLGEEIWSSPAVLSNGKT 869 99999999999999998777766666666666655 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00021 Beta-prop_CGLA 11 vlavsy.dGkilWknklsGfmnhdiwceDitgDgkdEilaanadGslycld.skGkllWkfkkneaPmyavcvvkk.ekkpYvvcGgfDkniyyL 102 v+a++ +G+ilW+n+ G + i Dgk ++ + d + y+ + ++Gk+lW f++ +a + + vv+k +++ +v G+ + niy + FUN_000247-T2 882 VFALNCaTGEILWDNETKGPVFS---SPTISYDGKT-VFFCSFDANCYAFNtESGKELWVFQTDSA-IQSSPVVSKvDGTLFV--GSSEGNIYAV 969 66666426999999999998754...4679999985.9999**********558*******99855.6666666662556554..9999999998 PP Beta-prop_CGLA 103 sa.kGe 107 ++ +G+ FUN_000247-T2 970 DSaTGK 975 651454 PP == domain 4 score: 13.1 bits; conditional E-value: 6e-05 Beta-prop_CGLA 5 ssYeGtvlavsy.dGkilWknklsGfmnhdiwceDitgDgkdEilaanadGslyclds.kGkllWkfkkneaPmyavcvvkkekkpYvvcGgf 95 s eG + av+ +Gk++W+ + G + i Dg+ i++ + +G++ +l + +G+l+W+fk+++a + + +k+ + Gg+ FUN_000247-T2 961 S-SEGNIYAVDSaTGKVKWTREGKGELFSSPF---IAPDGH--IFIGSGEGEVLALRQtDGSLVWSFKTESAVWSS-PRL--GKNGVLFIGGI 1044 4.489999987526999999998886655544...567775..*************8549*********9654333.333..45556778*** PP Beta-prop_CGLA 96 DkniyyLsa.kGelv 109 D+ +y L + +G++v FUN_000247-T2 1045 DTYLYALRSeDGQVV 1059 *****9965167766 PP == domain 5 score: 2.6 bits; conditional E-value: 0.094 Beta-prop_CGLA 49 aanadGslyclds.kGkllWkfkkneaP 75 + d ly+l s +G+++Wk+k+ P FUN_000247-T2 1041 IGGIDTYLYALRSeDGQVVWKYKTD-GP 1067 5667899****8538*******986.44 PP >> JmjC_2 JmjC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 5.8e-09 6.4e-06 36 118 .. 241 338 .. 211 347 .. 0.58 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 5.8e-09 JmjC_2 36 egvgpHyDeydvfilQleGkkrWrvgk...................pkeeeqeekseeelklldef..epvedlvLepGDlLYlPrgliHqgvaee 110 ++ H D y ++ ++G+k v + p + ++ +lk++ ++ + +vL++GD+LY+P++++H+ ++ + FUN_000247-T2 241 TSSSLHNDGYQNLLAVISGSKEVLVANsdnaeylyannyttipglsP-----VNPESVDLKKFPNVskVSFHKVVLKAGDILYIPQHWWHHVRSYN 331 45556666666666666666666666555655555544433222111.....112223333333332134689******************99987 PP JmjC_2 111 esltlsvg 118 + +++++ FUN_000247-T2 332 -CPNIAIS 338 .5444444 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.1 2.2e-05 0.025 21 130 .. 746 813 .. 729 843 .. 0.62 2 ! 8.0 0.0 0.002 2.2 135 214 .. 903 981 .. 855 1029 .. 0.53 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.2e-05 Beta-prop_WDR5 21 lasasaDktikiwdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSGsfDetvr 115 l +s D+ i +d+ +gk++ + +G s+ a++sd++++ ++ DDk++r d+ +g+l+ FUN_000247-T2 746 LYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLI-------------------------------- 808 344556666666666666666666666666666666666666666666666666665555554................................ PP Beta-prop_WDR5 116 lWdvrtgkclktlpa 130 ++ FUN_000247-T2 809 ----------WKFST 813 ..........44444 PP == domain 2 score: 8.0 bits; conditional E-value: 0.002 Beta-prop_WDR5 135 vsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvsfvkFspngkyiLastldstirLwdyekekvvktYk 214 s+ +++dg+++ +s+D + ++te+g+ l + +d+ + + s + + + + + +i +d +++kv+ t + FUN_000247-T2 903 FSSPTISYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSAIQS-SPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTRE 981 34445556666666666666666666666666655543332222.22233333344444444445555544444444333 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 0.0 7.8 8.7e+03 182 215 .. 251 283 .. 227 294 .. 0.59 2 ! 13.6 0.0 3.2e-05 0.035 67 207 .. 745 884 .. 741 890 .. 0.77 3 ! 8.0 0.0 0.0016 1.8 25 147 .. 874 994 .. 863 1019 .. 0.70 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 7.8 WDR55 182 llslalvkeekkvvvGsseGklylfnwgefgahs 215 + la++ k v+v++s+ + yl+ +++ ++ FUN_000247-T2 251 QNLLAVISGSKEVLVANSDNAEYLYA-NNYTTIP 283 34466777777888888888888885.4455555 PP == domain 2 score: 13.6 bits; conditional E-value: 3.2e-05 WDR55 67 klfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtlt 162 +l+ s D+ i ++d+ +gk+k+k+ +a+e ++ d +++ G dd ++ D + + +++++ + s+ v + L + dG++ FUN_000247-T2 745 TLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGAITSSTRVGP-DGSLYFGCLDGYFY 839 688888999999999999999999999999999999999999999999999999999999999999887766655555554.55678888888888 PP WDR55 163 vfnirkkklevqseeyeeellslalvkeekkvvvGs.seGklylfn 207 ++n +l+ + + ee s a++ ++k + +Gs +G+ ++f FUN_000247-T2 840 AINPD-GSLKWKQNLGEEIWSSPAVLSNGKTLFIGSmADGAANVFA 884 88865.5566776777777777788888888888763467777775 PP == domain 3 score: 8.0 bits; conditional E-value: 0.0016 WDR55 25 gtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllvid..enllatGdddGt 118 ++ dG ++ ++ ++e l+ e++ + + s dGk++f +s D ++ ++++e+gk ++ +++ s+i+s v++ + +l+ G +G+ FUN_000247-T2 874 SMADGAANVFALNCATGE--ILWDNETKGPVFSSPTISYDGKTVFFCSFDANCYAFNTESGKELWVFQTD--SAIQSSPVVSkvDGTLFVGSSEGN 965 455788888888887664..6888888888888889999*****************99999988888744..444444333311446677888899 PP WDR55 119 vklWDlRkkkavmelkehedyisdlvvde 147 + D + k ++ + + s+ + FUN_000247-T2 966 IYAVDSATGKVKWTREGKGELFSSPFIAP 994 88888777776666666666666655555 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 0.1 0.0002 0.22 40 118 .. 742 819 .. 709 885 .. 0.75 2 ? 5.4 0.0 0.016 18 38 131 .. 909 1002 .. 875 1050 .. 0.62 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.0002 Beta-prop_WDR3_1st 40 dgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvts 118 ++++l ++d +i +d+ sg+++ ++ + + af++dg+ + +G D+++ D v+++ +++++ +++ts FUN_000247-T2 742 RDSTLYLSSDDHWIYAFDAVSGKMKWKYGTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFST-GGAITS 819 4567888999******************************************************99999864.345555 PP == domain 2 score: 5.4 bits; conditional E-value: 0.016 Beta-prop_WDR3_1st 38 spdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvafleekk 126 s dgk++ + d + +++esg+ +f+ ++ ++ +k + +L+ Gs++ +i +D +++ ++ +g + s + ++++ FUN_000247-T2 909 SYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGELFSSPFIAPDGH 997 55566666666666666666666666666666665556666666666666666666666666666666555555444444444444444 PP Beta-prop_WDR3_1st 127 vlvss 131 + + s FUN_000247-T2 998 IFIGS 1002 44444 PP >> SSL_N Strictosidine synthase-like, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 6.8 7.5e+03 30 45 .. 742 757 .. 737 758 .. 0.77 2 ! 6.6 0.1 0.009 10 27 41 .. 822 836 .. 820 841 .. 0.88 3 ? 5.2 0.0 0.024 27 30 44 .. 953 967 .. 949 969 .. 0.87 4 ? 0.7 0.0 0.64 7.1e+02 28 44 .. 992 1008 .. 991 1010 .. 0.89 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 6.8 SSL_N 30 adGrlYtgladGrIvR 45 +d +lY +++d +I+ FUN_000247-T2 742 RDSTLYLSSDDHWIYA 757 67789***99988875 PP == domain 2 score: 6.6 bits; conditional E-value: 0.009 SSL_N 27 avdadGrlYtgladG 41 v++dG lY+g +dG FUN_000247-T2 822 RVGPDGSLYFGCLDG 836 589***********9 PP == domain 3 score: 5.2 bits; conditional E-value: 0.024 SSL_N 30 adGrlYtgladGrIv 44 dG+l++g+ +G+I+ FUN_000247-T2 953 VDGTLFVGSSEGNIY 967 59************9 PP == domain 4 score: 0.7 bits; conditional E-value: 0.64 SSL_N 28 vdadGrlYtgladGrIv 44 + +dG ++ g+ +G+++ FUN_000247-T2 992 IAPDGHIFIGSGEGEVL 1008 579***********998 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.0 0.0034 3.8 30 81 .. 767 816 .. 748 821 .. 0.81 2 ? -1.7 0.0 4.4 4.8e+03 48 81 .. 910 943 .. 883 951 .. 0.83 3 ? 1.1 0.0 0.61 6.8e+02 48 72 .. 953 976 .. 930 986 .. 0.75 4 ? 2.0 0.0 0.31 3.5e+02 13 78 .. 1001 1064 .. 994 1070 .. 0.73 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0034 ANAPC4_WD40 30 wklseekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksd 81 wk d+ ++ a++ dG++ +++d ++r ld+ sg l+ ++s++ FUN_000247-T2 767 WKY--GTADEGGSKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTGGA 816 555..34444446789******************************998765 PP == domain 2 score: -1.7 bits; conditional E-value: 4.4 ANAPC4_WD40 48 pdGklLavaysdgevrlldvesgklvhslsaksd 81 dGk + d ++ ++ esgk + +++ s FUN_000247-T2 910 YDGKTVFFCSFDANCYAFNTESGKELWVFQTDSA 943 6888888888899999999999999988887765 PP == domain 3 score: 1.1 bits; conditional E-value: 0.61 ANAPC4_WD40 48 pdGklLavaysdgevrlldvesgkl 72 dG L v+ s+g++ +d+ +gk+ FUN_000247-T2 953 VDG-TLFVGSSEGNIYAVDSATGKV 976 455.477999***********9997 PP == domain 4 score: 2.0 bits; conditional E-value: 0.31 ANAPC4_WD40 13 atedgevllkRl.nwqrvwklseekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsa 78 ++ +gevl+ R ++ vw++ k++s+v s + +L ++ d+ + l +e+g++v ++++ FUN_000247-T2 1001 GSGEGEVLALRQtDGSLVWSF---KTESAVWSSPRLGKNGVLFIGGIDTYLYALRSEDGQVVWKYKT 1064 566677777665488889998...6666666655555666888888888888888999888887766 PP >> Cupin_1 Cupin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 2.1e-05 0.023 54 111 .. 250 338 .. 227 348 .. 0.84 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.1e-05 Cupin_1 54 ateilyvleGegrvgfvvsnng...............................nrvfhkk.lreGdvfvvPqglvhfqynsgkepavafv 111 +l v+ G+ v ++ s+n+ + +fhk+ l++Gd++++Pq++ h +++ + p+ a++ FUN_000247-T2 250 YQNLLAVISGSKEVLVANSDNAeylyannyttipglspvnpesvdlkkfpnvsKVSFHKVvLKAGDILYIPQHWWHHVRSYN-CPNIAIS 338 56778899999997777777779999999999999999999999999999998999*********************99996.7777776 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 5.7 6.4e+03 5 44 .. 244 285 .. 242 307 .. 0.64 2 ? 2.8 0.0 0.077 85 55 224 .. 777 817 .. 725 843 .. 0.66 3 ? 9.0 0.0 0.00095 1.1 54 126 .. 903 977 .. 878 1026 .. 0.56 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 5.7 WD40_CDC20-Fz 5 glrdDfylnlldWsk.knvlava.lgssvylwnaetgevkel 44 +l +D y nll+ + ++ + va ++ yl+ ++ ++ l FUN_000247-T2 244 SLHNDGYQNLLAVISgSKEVLVAnSDNAEYLYANNYTTIPGL 285 688999999987543234444441455557777666666555 PP == domain 2 score: 2.8 bits; conditional E-value: 0.077 WD40_CDC20-Fz 55 tsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalawnenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrll 150 + +++++dg+++ +Gt++ +++ +d+ +++ + ++++ FUN_000247-T2 777 SKCAFNSDGTVVYCGTDDKSLRALDAVSGSLIWKFSTG---------------------------------------------------------- 814 55666666666666666666666666666555554443.......................................................... PP WD40_CDC20-Fz 151 AsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgsqv 224 + FUN_000247-T2 815 -----------------------------------------------------------------------GAI 817 .......................................................................333 PP == domain 3 score: 9.0 bits; conditional E-value: 0.00095 WD40_CDC20-Fz 54 vtsvkwsedgelLavGtssgevelwdvekkkklrtleghs..srvgalawnenllssGsrdgkilhhDvrtkele 126 +s s dg+++ + + + +++ +++e++k+l ++++s ++ +++ + +l++Gs++g+i+ D t +++ FUN_000247-T2 903 FSSPTISYDGKTVFFCSFDANCYAFNTESGKELWVFQTDSaiQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVK 977 555555555555555555555555555555555444433211334444444445555555555555555544433 PP >> Cupin_2 Cupin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 0.00019 0.21 36 57 .. 307 328 .. 301 331 .. 0.90 2 ? -2.4 0.0 5.3 5.9e+03 14 38 .. 677 702 .. 672 703 .. 0.76 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00019 Cupin_2 36 eevvlkaGdsvyfpagvpHrfr 57 ++vvlkaGd++y+p + +H++r FUN_000247-T2 307 HKVVLKAGDILYIPQHWWHHVR 328 589*****************97 PP == domain 2 score: -2.4 bits; conditional E-value: 5.3 Cupin_2 14 hrHpge.effyVleGeleltvdgeev 38 h ++ e+f l+G++++ dg ++ FUN_000247-T2 677 HLNNHDrEYFKNLDGKIVVPDDGPPY 702 555555799999****9998888776 PP >> JmjC JmjC domain, hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 9.6e-05 0.11 76 105 .. 302 331 .. 277 341 .. 0.84 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 9.6e-05 JmjC 76 egipvyrivqkpgefVivfpgayHavfnlg 105 +++ ++++v k+g++++++ ++H v ++ FUN_000247-T2 302 SKVSFHKVVLKAGDILYIPQHWWHHVRSYN 331 5799**********************9875 PP >> SUKH-4 SUKH-4 immunity protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 1 1.1e+03 79 110 .. 867 901 .. 846 907 .. 0.77 2 ? 8.0 0.0 0.0036 4 67 111 .. 942 986 .. 922 994 .. 0.83 3 ? 0.2 0.0 0.9 9.9e+02 63 104 .. 1019 1061 .. 994 1074 .. 0.58 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 1 SUKH-4 79 esllvLGal...egaslvldpatGaVlavsleade 110 ++ l +G++ ++++l+ atG++l+ +++++ FUN_000247-T2 867 GKTLFIGSMadgAANVFALNCATGEILWDNETKGP 901 5678889998888999***********98777766 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0036 SUKH-4 67 aaersaelpadaesllvLGalegaslvldpatGaVlavsleader 111 a +s ++ +++++ l +G+ eg+ +++d atG+V + +++++e+ FUN_000247-T2 942 SAIQSSPVVSKVDGTLFVGSSEGNIYAVDSATGKVKWTREGKGEL 986 455667777899999**********************99999876 PP == domain 3 score: 0.2 bits; conditional E-value: 0.9 SUKH-4 63 lalvaaersaelpa.daesllvLGalegaslvldpatGaVlav 104 +++ +++ + +p+ + ++l +G ++ ++l+ ++G+V++ FUN_000247-T2 1019 WSFKTESAVWSSPRlGKNGVLFIGGIDTYLYALRSEDGQVVWK 1061 3344444444444424556666666666666677777776665 PP >> DUF7957 Domain of unknown function (DUF7957) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.00027 0.3 49 106 .. 922 977 .. 919 981 .. 0.80 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00027 DUF7957 49 rNviafdk.dGnklWeieelpeekeskpyveiavedgeLiasswnsyeykiDietGeve 106 N af++ G++lW + ++ +s+p +++ dg L ++s +++ y +D +tG+v+ FUN_000247-T2 922 ANCYAFNTeSGKELWVFQ-TDSAIQSSP--VVSKVDGTLFVGSSEGNIYAVDSATGKVK 977 5888887526999**999.555555555..456789*********************97 PP >> PD40 WD40-like Beta Propeller Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.1 8.3 9.2e+03 14 25 .. 821 831 .. 813 831 .. 0.73 2 ? -1.6 0.0 3.8 4.3e+03 13 32 .. 860 878 .. 859 883 .. 0.74 3 ? 8.1 0.4 0.0033 3.7 13 28 .. 905 920 .. 903 929 .. 0.93 4 ? 1.9 0.0 0.31 3.4e+02 13 26 .. 989 1002 .. 983 1016 .. 0.82 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 8.3 PD40 14 PsfSPDGkrlaF 25 ++ PDG +l+F FUN_000247-T2 821 TRVGPDG-SLYF 831 56669**.8888 PP == domain 2 score: -1.6 bits; conditional E-value: 3.8 PD40 13 ePsfSPDGkrlaFsSdrdsG 32 +P++ ++Gk+l S d G FUN_000247-T2 860 SPAVLSNGKTLFIGSMAD-G 878 69999*****98766555.5 PP == domain 3 score: 8.1 bits; conditional E-value: 0.0033 PD40 13 ePsfSPDGkrlaFsSd 28 +P++S DGk+ F+S+ FUN_000247-T2 905 SPTISYDGKTVFFCSF 920 7**************8 PP == domain 4 score: 1.9 bits; conditional E-value: 0.31 PD40 13 ePsfSPDGkrlaFs 26 +P++ PDG ++ s FUN_000247-T2 989 SPFIAPDGHIFIGS 1002 8*******777766 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.2 0.0031 3.4 17 36 .. 779 798 .. 777 801 .. 0.92 2 ? -1.2 0.1 4.9 5.4e+03 19 36 .. 908 925 .. 899 928 .. 0.81 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0031 WD40 17 lafspdgsllasgsdDgtvk 36 +af++dg+ +++g dD++++ FUN_000247-T2 779 CAFNSDGTVVYCGTDDKSLR 798 89***************998 PP == domain 2 score: -1.2 bits; conditional E-value: 4.9 WD40 19 fspdgsllasgsdDgtvk 36 +s dg+ ++ +s D +++ FUN_000247-T2 908 ISYDGKTVFFCSFDANCY 925 689999999999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1083 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 929 (0.0363672); expected 510.9 (0.02) Passed bias filter: 822 (0.0321785); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 23 (0.000900372); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 23 [number of targets reported over threshold] # CPU time: 0.53u 0.38s 00:00:00.91 Elapsed: 00:00:00.43 # Mc/sec: 10194.70 // Query: FUN_000248-T1 [L=113] Description: FUN_000248 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-09 38.3 14.9 2.4e-09 38.0 14.9 1.1 1 UPAR_LY6 u-PAR/Ly-6 domain 7.5e-05 23.9 15.3 0.0001 23.4 15.3 1.2 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.0045 18.1 12.3 0.0058 17.7 12.3 1.2 1 PLA2_inh Phospholipase A2 inhibitor ------ inclusion threshold ------ 0.016 15.6 0.3 0.022 15.2 0.3 1.2 1 Izumo-Ig Izumo-like Immunoglobulin domain 0.049 14.1 0.3 0.08 13.5 0.3 1.4 1 PTCB-BRCT twin BRCT domain 7.2 8.1 15.8 14 7.2 15.8 1.6 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 14.9 5.5e-13 2.4e-09 1 82 [] 4 91 .. 4 91 .. 0.91 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 5.5e-13 UPAR_LY6 1 qglrCysClgessssccssgs.sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCnsa 82 +gl+Cy Cl++ss+++c++++ C++g ++C+++ +k+++gg++++ + kgC c+++n++ ++ t++cc++dlCnsa FUN_000248-T1 4 HGLKCYGCLSTSSWADCHQQEiFCAPGLDTCAKVYFKVEEGGLSFTEHWKGCstTLVCNAKNSKLCKKavyGGECTINCCSGDLCNSA 91 689*************************************************8866788887777777666779************85 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 15.3 2.5e-08 0.0001 1 72 [] 6 89 .. 6 89 .. 0.83 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 2.5e-08 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCsesekyCvttvtsa....kskklisksCsss..Ceessselgvas.....vsvsCCqtdlCN 72 LkCy C +++s ++C +e C+ ++C +++ ++ s + k Cs++ C++++s+l +++ +++CC+ dlCN FUN_000248-T1 6 LKCYGCLSTSSWADCHqQEIFCAPGLDTCAKVYFKVeeggLSFTEHWKGCSTTlvCNAKNSKLCKKAvyggeCTINCCSGDLCN 89 89*************934568************9999998667888999*99888998887765543334449**********9 PP >> PLA2_inh Phospholipase A2 inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 12.3 1.4e-06 0.0058 10 82 .. 17 89 .. 6 90 .. 0.88 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 1.4e-06 PLA2_inh 10 GkdCegykeeCdsneDaCvtvllevssaplslrlihknCfssdlCkLekldvnigkelylrgkiaCCdeeeCe 82 dC++ + C+ D+C++v v ls++ k C + +C+ ++ + i+CC ++ C+ FUN_000248-T1 17 WADCHQQEIFCAPGLDTCAKVYFKVEEGGLSFTEHWKGCSTTLVCNAKNSKLCKKAVYGGECTINCCSGDLCN 89 369*********************************************99999998888999**********7 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.3 5.1e-06 0.022 19 81 .. 38 98 .. 30 105 .. 0.81 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 5.1e-06 Izumo-Ig 19 WHklseGltdYsFyrvwenssetllskgkestLtkpmvgledaGtYRCeLdtvksspatiihf 81 + k+ eG sF+ w+ s tl+ ++k+s L k++v + C+ d +s+ + +i+ FUN_000248-T1 38 YFKVEEG--GLSFTEHWKGCSTTLVCNAKNSKLCKKAVYGGECTINCCSGDLCNSAAIQVINV 98 5555555..3589**************************999999999999999988888865 PP >> PTCB-BRCT twin BRCT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.3 1.9e-05 0.08 19 52 .. 40 73 .. 32 85 .. 0.88 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.9e-05 PTCB-BRCT 19 lieamGaeytkdltkkvTHLicksgeGekykkAk 52 +e+ G ++t++++ T L+c+ +++ +kkA+ FUN_000248-T1 40 KVEEGGLSFTEHWKGCSTTLVCNAKNSKLCKKAV 73 58899****************************8 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 15.8 0.0032 14 1 78 [. 6 91 .. 6 92 .. 0.66 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0032 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd.gsCfssvekettgkik..vvkkgclsre....qdpleCktsnkpeqlnsrieCCktdfCNkn 78 lkCy C +++ C+++e + c +C + k +g kgc + ++ +Ck++ + ++ i CC++d+CN++ FUN_000248-T1 6 LKCYgCLSTSswadCHQQE--IFCAPGlDTCAKVYFKVEEGGLSftEHWKGCSTTLvcnaKNSKLCKKAVYGGE--CTINCCSGDLCNSA 91 6899998888888898888..88887777775555544444443334456665555432344555888777776..48**********86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 931 (0.0364455); expected 510.9 (0.02) Passed bias filter: 306 (0.0119789); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1150.12 // Query: FUN_000250-T1 [L=165] Description: FUN_000250 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-07 30.8 20.0 6.4e-07 30.2 20.0 1.3 1 UPAR_LY6 u-PAR/Ly-6 domain 0.0037 18.4 21.2 0.0065 17.7 21.2 1.4 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.0049 18.3 18.6 0.008 17.6 18.6 1.3 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 20.0 7.5e-11 6.4e-07 1 81 [. 57 142 .. 57 143 .. 0.96 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 7.5e-11 UPAR_LY6 1 qglrCysClgessssccssgs.sC.pkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig.sltvtesccqsdlCns 81 ++l+C+ C + ss+++c++++ +C + d C+++ +k + +g + + +gC ++ c++++++s + + + +++cc++dlCn FUN_000250-T1 57 HSLKCFYCASSSSWDDCKTQKiTCeSSADARCYKAYVKTKLRGDTYTGYERGCltETLCETVKTSSLCKgKEDCQVNCCSGDLCNT 142 589****************************************************9********999988999************6 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 21.2 7.6e-07 0.0065 1 72 [] 59 141 .. 59 141 .. 0.78 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 7.6e-07 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCses.ekyCvttvtsa....kskklisksCsss..Ceessselgva.s..vsvsCCqtdlCN 72 LkC+ C +++s ++C+ ++ +C++s + C ++++++ + + +++ C ++ Ce+ +++ + + +v+CC+ dlCN FUN_000250-T1 59 LKCFYCASSSSWDDCKtQKITCESSaDARCYKAYVKTklrgDTYTGYERGCLTEtlCETVKTSSLCKgKedCQVNCCSGDLCN 141 89*************945569*8762568***9999999986678899***887679855444433222349**********9 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 18.6 9.4e-07 0.008 1 78 [. 59 143 .. 59 144 .. 0.74 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 9.4e-07 Activin_recp 1 lkC.yCetsk....Ceedesnvtcetd..gsCfssveke..ttgkikvvkkgclsre.qdpleCktsnkpeqlnsrieCCktdfCNkn 78 lkC yC +s+ C++++ +tce C+++ k + + +++gcl++ ++ + ++ ++ + ++ CC++d+CN + FUN_000250-T1 59 LKCfYCASSSswddCKTQK--ITCESSadARCYKAYVKTklRGDTYTGYERGCLTETlCETVKTSSLC-KGKEDCQVNCCSGDLCNTA 143 68966*99989999***99..66666655*****9988765444455899*****9944444444444.4445779**********75 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (165 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1117 (0.0437268); expected 510.9 (0.02) Passed bias filter: 342 (0.0133881); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1663.64 // Query: FUN_000252-T1 [L=124] Description: FUN_000252 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-06 29.4 21.5 1.5e-06 29.1 21.5 1.1 1 UPAR_LY6 u-PAR/Ly-6 domain 0.00043 21.5 22.4 0.00057 21.1 22.4 1.2 1 Toxin_TOLIP Snake toxin and toxin-like protein ------ inclusion threshold ------ 0.5 11.9 20.2 0.71 11.4 20.2 1.2 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.1 21.5 1.8e-10 1.5e-06 1 81 [. 17 101 .. 17 102 .. 0.94 Alignments for each domain: == domain 1 score: 29.1 bits; conditional E-value: 1.8e-10 UPAR_LY6 1 qglrCysClgessssccssgs.sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig.sltvtesccqsdlCns 81 ++l+Cy C++ ss+++c++++ +C+ +++ C+++ +k++++g++++ k C ++sc++ ++ + + + +cc++dlCn FUN_000252-T1 17 HSLKCYYCVSSSSWDDCKTQEiTCTSSANRCAKAYTKYKQDGNTFTDYGKLClqESSCKDYKSGPMCQgKEECQLDCCSGDLCNT 101 589***************************************************9999999998887778899***********6 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 22.4 6.7e-08 0.00057 1 72 [] 19 100 .. 19 100 .. 0.79 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 6.7e-08 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCsesekyCvttvtsa....kskklisksCsss..Ceessselgva...svsvsCCqtdlCN 72 LkCy C +++s ++C+ +e +C++s++ C +++t+ ++ + + k C ++ C++ +s + + ++ CC+ dlCN FUN_000252-T1 19 LKCYYCVSSSSWDDCKtQEITCTSSANRCAKAYTKYkqdgNTFTDYGKLCLQEssCKDYKSGPMCQgkeECQLDCCSGDLCN 100 89*************945679**********9999998886688899***87644885554332221126999********9 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 20.2 8.3e-05 0.71 1 78 [. 19 102 .. 19 103 .. 0.65 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 8.3e-05 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd....gsCfssveke.....ttgkikvvkkgclsreqdpleCktsnkpeqlnsrieCCktdfCNkn 78 lkCy C +s+ C+++e +tc+ + +++ +++ + gk + +++ ++++ +C+ +++ + ++CC++d+CN + FUN_000252-T1 19 LKCYyCVSSSswddCKTQE--ITCTSSanrcAKAYTKYKQDgntftDYGKL-CLQESSCKDYKSGPMCQGKEECQ-----LDCCSGDLCNTA 102 6897699888889999999..666665524555566666665533222333.66666666666666677666655.....79********75 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1330 (0.052065); expected 510.9 (0.02) Passed bias filter: 460 (0.0180074); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1233.32 // Query: FUN_000253-T1 [L=88] Description: FUN_000253 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (88 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 349 (0.0136622); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 906.02 // Query: FUN_000254-T1 [L=132] Description: FUN_000254 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 578 (0.0226267); expected 510.9 (0.02) Passed bias filter: 465 (0.0182032); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1373.01 // Query: FUN_000255-T1 [L=110] Description: FUN_000255 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-06 29.1 14.9 1.8e-06 28.8 14.9 1.1 1 UPAR_LY6 u-PAR/Ly-6 domain 0.0011 20.1 16.3 0.0014 19.8 16.3 1.2 1 Toxin_TOLIP Snake toxin and toxin-like protein ------ inclusion threshold ------ 0.024 16.1 14.0 0.031 15.7 14.0 1.2 1 Activin_recp Activin types I and II receptor domain 0.13 12.9 11.5 0.16 12.7 11.5 1.1 1 UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 3.1 8.3 6.1 0.22 12.0 1.0 1.7 2 TIG_plexin TIG domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 14.9 3.5e-10 1.8e-06 1 81 [. 3 87 .. 3 88 .. 0.95 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 3.5e-10 UPAR_LY6 1 qglrCysClgessssccssgs.sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig.sltvtesccqsdlCns 81 ++l+Cy C++ ss+++c++++ +C+ +++ +++ +k++++g+ + k+C ++sc++ ++ + ++ + +cc++dlCn FUN_000255-T1 3 HSLKCYFCVSSSSWDDCKTQEiTCTSPANRYAKAYTKQKIDGNIITGYGKSCvlESSCKDYKSGPMCQgKAECQLDCCSGDLCNI 87 589***************************************************9999999999888879**************5 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 16.3 2.8e-07 0.0014 1 72 [] 5 86 .. 5 86 .. 0.69 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 2.8e-07 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCsesekyCvttvtsa....kskklisksCs..ssCeessse...lgvasvsvsCCqtdlCN 72 LkCy C +++s ++C+ +e +C++ ++ +++t++ + + + ksC+ ssC++ +s +g+a+ ++ CC+ dlCN FUN_000255-T1 5 LKCYFCVSSSSWDDCKtQEITCTSPANRYAKAYTKQkidgNIITGYGKSCVleSSCKDYKSGpmcQGKAECQLDCCSGDLCN 86 89*************945679*987765555555555766444556799963255885554311134446999********9 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 14.0 6.1e-06 0.031 1 76 [. 5 86 .. 5 89 .. 0.66 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 6.1e-06 Activin_recp 1 lkCy.Cetsk....CeedesnvtcetdgsCfssveke..ttgkik.vvkkgclsre.qdple....CktsnkpeqlnsrieCCktdfCN 76 lkCy C +s+ C+++e +tc+ + +++ + +g+i+ + k+c+ + ++++ C+ ++ + +++CC++d+CN FUN_000255-T1 5 LKCYfCVSSSswddCKTQE--ITCTSPANRYAKAYTKqkIDGNIItGYGKSCVLESsCKDYKsgpmCQGKA-----ECQLDCCSGDLCN 86 69*98998888999*****..99999955555443333468888775666677766444444211144444.....4478********* PP >> UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 11.5 3.1e-05 0.16 6 92 .. 3 89 .. 1 101 [. 0.77 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 3.1e-05 UPAR_LY6_2 6 ksfkcftcekaadnyecnrwaedkycpr.etkycltvhklesegksvs.vtkkcaaleecllvgcreskeeehkec.tsccegnicnvel 92 +s+kc+ c +++ +c ++ c +y + k + +g+ ++ k c+ ++ c+ + + ++ ec cc g +cn+ FUN_000255-T1 3 HSLKCYFCVSSSSWDDCKTQ--EITCTSpANRYAKAYTKQKIDGNIITgYGKSCVLESSCKDYKSGPMCQ-GKAECqLDCCSGDLCNIAA 89 699**********99**864..5555441568999999999999976527899*******9887766655.56666258********975 PP >> TIG_plexin TIG domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 1.0 4.3e-05 0.22 25 63 .. 3 41 .. 1 48 [. 0.88 2 ? -1.5 0.3 0.68 3.5e+03 41 49 .. 68 76 .. 46 91 .. 0.58 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 4.3e-05 TIG_plexin 25 eslsCvfgdleeseaevedntvkCssPspsklppitkgk 63 sl+C+f +++s + ++++C+sP + + tk+k FUN_000255-T1 3 HSLKCYFCVSSSSWDDCKTQEITCTSPANRYAKAYTKQK 41 589*******9****************999888877765 PP == domain 2 score: -1.5 bits; conditional E-value: 0.68 TIG_plexin 41 vedntvkCs 49 + +++ +C+ FUN_000255-T1 68 MCQGKAECQ 76 224455554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1095 (0.0428655); expected 510.9 (0.02) Passed bias filter: 425 (0.0166373); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1121.69 // Query: FUN_000256-T1 [L=472] Description: FUN_000256 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (472 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1111 (0.0434919); expected 510.9 (0.02) Passed bias filter: 563 (0.0220395); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4594.91 // Query: FUN_000257-T1 [L=129] Description: FUN_000257 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-08 34.5 18.9 3.8e-08 34.2 18.9 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain 3.4e-05 25.0 19.6 4.8e-05 24.5 19.6 1.3 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.005 18.0 16.4 0.01 17.0 16.4 1.5 1 PLA2_inh Phospholipase A2 inhibitor ------ inclusion threshold ------ 0.24 12.8 17.5 0.33 12.4 17.5 1.2 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.2 18.9 6e-12 3.8e-08 1 81 [. 17 101 .. 17 102 .. 0.95 Alignments for each domain: == domain 1 score: 34.2 bits; conditional E-value: 6e-12 UPAR_LY6 1 qglrCysClgessssccssgs.sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig.sltvtesccqsdlCns 81 ++l+Cy C+++ss+++c++++ +Cp +++ C ++ +k+++gg + + k+C ++sc++ ++ + + +cc++dlCn FUN_000257-T1 17 HSLKCYYCFSTSSWDDCKTQEiTCPSSANLCSKAYTKVKQGGITITGYEKSCfaESSCKDYKSGPLCQrAEECQLDCCSGDLCNT 101 589***********************************************************9999996778999*********5 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 19.6 7.5e-09 4.8e-05 1 72 [] 19 100 .. 19 100 .. 0.79 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 7.5e-09 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCsesekyCvttvtsa....kskklisksCsss..Ceessselgva...svsvsCCqtdlCN 72 LkCy C +++s ++C+ +e +C++s++ C +++t++ + + ++ksC ++ C++ +s + + ++ CC+ dlCN FUN_000257-T1 19 LKCYYCFSTSSWDDCKtQEITCPSSANLCSKAYTKVkqggITITGYEKSCFAEssCKDYKSGPLCQraeECQLDCCSGDLCN 100 89*************945679***********999988775577789***76534886665543331235999********9 PP >> PLA2_inh Phospholipase A2 inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 16.4 1.6e-06 0.01 2 83 .] 20 101 .. 19 101 .. 0.86 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 1.6e-06 PLA2_inh 2 sCeiCvnlG..kdCegykeeCdsneDaCvtvllevssaplslrlihknCfssdlCkLekldvnigkelylrgkiaCCdeeeCet 83 +C +C + dC++ + +C s + C++ + v + + ++ +k+Cf+ + Ck + + + + CC ++ C+t FUN_000257-T1 20 KCYYCFSTSswDDCKTQEITCPSSANLCSKAYTKVKQGGITITGYEKSCFAESSCKD--YKSGPLCQRAEECQLDCCSGDLCNT 101 688887765227*******************************************94..456666777778999********86 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 17.5 5.2e-05 0.33 1 77 [. 19 101 .. 19 103 .. 0.64 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 5.2e-05 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd.gsCfssvekettgkik..vvkkgclsre.qdple....CktsnkpeqlnsrieCCktdfCNk 77 lkCy C +++ C+++e +tc C ++ +k ++g i ++k+c+ + ++++ C+ +++ +++CC++d+CN FUN_000257-T1 19 LKCYyCFSTSswddCKTQE--ITCPSSaNLCSKAYTKVKQGGITitGYEKSCFAESsCKDYKsgplCQRAEEC-----QLDCCSGDLCNT 101 6896688777778899998..7777766667666666655555545566777777755555532225544444.....68*********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1078 (0.0422); expected 510.9 (0.02) Passed bias filter: 381 (0.0149149); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1314.49 // Query: FUN_000257-T2 [L=149] Description: FUN_000257 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-08 34.0 18.9 5.8e-08 33.6 18.9 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain 5.3e-05 24.3 19.6 7.2e-05 23.9 19.6 1.2 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.0072 17.4 16.3 0.014 16.5 16.3 1.5 1 PLA2_inh Phospholipase A2 inhibitor ------ inclusion threshold ------ 0.35 12.3 17.6 0.48 11.9 17.6 1.2 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.6 18.9 9.1e-12 5.8e-08 1 81 [. 17 101 .. 17 102 .. 0.95 Alignments for each domain: == domain 1 score: 33.6 bits; conditional E-value: 9.1e-12 UPAR_LY6 1 qglrCysClgessssccssgs.sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig.sltvtesccqsdlCns 81 ++l+Cy C+++ss+++c++++ +Cp +++ C ++ +k+++gg + + k+C ++sc++ ++ + + +cc++dlCn FUN_000257-T2 17 HSLKCYYCFSTSSWDDCKTQEiTCPSSANLCSKAYTKVKQGGITITGYEKSCfaESSCKDYKSGPLCQrAEECQLDCCSGDLCNT 101 589***********************************************************9999996778999*********5 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 19.6 1.1e-08 7.2e-05 1 72 [] 19 100 .. 19 100 .. 0.79 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 1.1e-08 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCsesekyCvttvtsa....kskklisksCsss..Ceessselgva...svsvsCCqtdlCN 72 LkCy C +++s ++C+ +e +C++s++ C +++t++ + + ++ksC ++ C++ +s + + ++ CC+ dlCN FUN_000257-T2 19 LKCYYCFSTSSWDDCKtQEITCPSSANLCSKAYTKVkqggITITGYEKSCFAEssCKDYKSGPLCQraeECQLDCCSGDLCN 100 89*************945679***********999988775577789***76534886665543331235999********9 PP >> PLA2_inh Phospholipase A2 inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 16.3 2.2e-06 0.014 2 83 .] 20 101 .. 19 101 .. 0.86 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 2.2e-06 PLA2_inh 2 sCeiCvnlG..kdCegykeeCdsneDaCvtvllevssaplslrlihknCfssdlCkLekldvnigkelylrgkiaCCdeeeCet 83 +C +C + dC++ + +C s + C++ + v + + ++ +k+Cf+ + Ck + + + + CC ++ C+t FUN_000257-T2 20 KCYYCFSTSswDDCKTQEITCPSSANLCSKAYTKVKQGGITITGYEKSCFAESSCKD--YKSGPLCQRAEECQLDCCSGDLCNT 101 688887765227*******************************************94..456666777778999********86 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 17.6 7.5e-05 0.48 1 77 [. 19 101 .. 19 103 .. 0.64 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 7.5e-05 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd.gsCfssvekettgkik..vvkkgclsre.qdple....CktsnkpeqlnsrieCCktdfCNk 77 lkCy C +++ C+++e +tc C ++ +k ++g i ++k+c+ + ++++ C+ +++ +++CC++d+CN FUN_000257-T2 19 LKCYyCFSTSswddCKTQE--ITCPSSaNLCSKAYTKVKQGGITitGYEKSCFAESsCKDYKsgplCQRAEEC-----QLDCCSGDLCNT 101 6896688777778899998..7777766667666666655555545566777777755555532225544444.....68*********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (149 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 924 (0.0361715); expected 510.9 (0.02) Passed bias filter: 346 (0.0135447); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1516.99 // Query: FUN_000259-T1 [L=125] Description: FUN_000259 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-08 34.2 21.5 4.6e-08 33.9 21.5 1.1 1 UPAR_LY6 u-PAR/Ly-6 domain 0.00024 22.2 22.7 0.00032 21.8 22.7 1.2 1 Toxin_TOLIP Snake toxin and toxin-like protein ------ inclusion threshold ------ 0.17 13.4 20.1 0.22 13.0 20.1 1.2 1 Activin_recp Activin types I and II receptor domain 0.38 9.9 13.0 0.39 9.8 13.0 1.0 1 Peptidase_M8 Leishmanolysin 5.9 7.7 16.9 11 6.8 4.3 2.2 2 zf-C3HC4_IRF-2BP1_2 IRF-2BP1/2 C3HC4 zinc finger domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.9 21.5 9.1e-12 4.6e-08 1 81 [. 17 102 .. 17 103 .. 0.94 Alignments for each domain: == domain 1 score: 33.9 bits; conditional E-value: 9.1e-12 UPAR_LY6 1 qglrCysClgessssccssgs.sC.pkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig.sltvtesccqsdlCns 81 ++l+Cy C++ ss+++c++++ +C + +d Cv++ +k + + + + kgC ++ c++ +++s + + + +++cc++dlCn FUN_000259-T1 17 HSLKCYFCVSSSSWDDCKTQKiTCeSSDDARCVKGYFKTKLREDTYTSYEKGCltESACKSAKTSSLCKgKEDCQVNCCSGDLCNT 102 589*********************9999***************************99999999988888799*************6 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 22.7 6.3e-08 0.00032 1 72 [] 19 101 .. 19 101 .. 0.79 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 6.3e-08 Toxin_TOLIP 1 LkCytCeeeksnsnCl.ketkCsesek.yCvttvtsa....kskklisksCsss..Ceessselgva.s..vsvsCCqtdlCN 72 LkCy C +++s ++C+ ++ +C++s++ Cv+ + ++ + ++++k C ++ C++ +++ + + +v+CC+ dlCN FUN_000259-T1 19 LKCYFCVSSSSWDDCKtQKITCESSDDaRCVKGYFKTklreDTYTSYEKGCLTEsaCKSAKTSSLCKgKedCQVNCCSGDLCN 101 89*************945569*9876538***999999998668999****866559865555433322359**********9 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 20.1 4.4e-05 0.22 1 78 [. 19 103 .. 19 104 .. 0.72 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.4e-05 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd..gsCfssveke..ttgkikvvkkgclsre.qdpleCktsnkpeqlnsrieCCktdfCNkn 78 lkCy C +s+ C++++ +tce C + k ++ + ++kgcl++ ++ ++ ++ + ++ CC++d+CN + FUN_000259-T1 19 LKCYfCVSSSswddCKTQK--ITCESSddARCVKGYFKTklREDTYTSYEKGCLTESaCKSAKTSSLC-KGKEDCQVNCCSGDLCNTA 103 6998898888888999999..777776667785554443336777779*********54444444444.4445779**********75 PP >> Peptidase_M8 Leishmanolysin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 13.0 7.7e-05 0.39 422 520 .. 22 120 .. 8 125 .] 0.77 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 7.7e-05 Peptidase_M8 422 gaCnqdpssadpslkefnv.fsdasRCldgalrpkqstgiteeynglCa.nvkCdrakrtysvqvygssgyvaCtpGesvelatvsaafvegsyiv 515 +C +s d + ++ sd +RC++g ++ k + ++++y + C + C++a +t s +++ v+C G+ + a+++ ++ FUN_000259-T1 22 YFCVSSSSWDDCKTQKITCeSSDDARCVKGYFKTKLREDTYTSYEKGCLtESACKSA-KTSSLCKGKEDCQVNCCSGDLCNTASTK-VVSAVFMVL 115 47888888888888885442689**************99999999988626778777.7888888899**********99999887.334444556 PP Peptidase_M8 516 Cpayv 520 C+ + FUN_000259-T1 116 CAFLA 120 66555 PP >> zf-C3HC4_IRF-2BP1_2 IRF-2BP1/2 C3HC4 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 4.3 0.0022 11 13 51 .. 7 45 .. 2 59 .. 0.85 2 ? 6.7 4.8 0.0024 12 27 59 .. 75 107 .. 69 117 .. 0.80 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0022 zf-C3HC4_IRF-2BP1_2 13 shfvqCpsvkeHkfCfeCtkksikkqatkkevyCPSgek 51 f+ C sv + C+ C +s +++ +++++ C S + FUN_000259-T1 7 FAFILCVSVGHSLKCYFCVSSSSWDDCKTQKITCESSDD 45 57999**9999999********************99864 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0024 zf-C3HC4_IRF-2BP1_2 27 CfeCtkksikkqatkkevyCPSgekCplkgskv 59 C + ++s++k +++ +v+C Sg+ C +++kv FUN_000259-T1 75 CKSAKTSSLCKGKEDCQVNCCSGDLCNTASTKV 107 666677889999999***********9987754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (125 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1441 (0.0564103); expected 510.9 (0.02) Passed bias filter: 417 (0.0163241); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1289.16 // Query: FUN_000260-T1 [L=311] Description: FUN_000260 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.4 1 LysM LysM domain Domain annotation for each model (and alignments): >> LysM LysM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 0.0 7.5e-10 1.9e-05 5 43 .] 115 154 .. 111 154 .. 0.91 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 7.5e-10 LysM 5 kGDTLssIAkrygitveqLaelNglsspn.lkvGqkLkip 43 + DTL ++A +yg+tveqL++ N++ ++ ++ + Lk+p FUN_000260-T1 115 PSDTLQGLAIKYGVTVEQLRRTNKIWTNDnIHLLKILKVP 154 66***************************99988888887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (311 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 941 (0.036837); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3054.73 // Query: FUN_000261-T1 [L=164] Description: FUN_000261 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-05 24.5 0.0 9.9e-05 22.8 0.0 1.7 1 TLD TLDc domain Domain annotation for each model (and alignments): >> TLD TLDc domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.0 3.9e-09 9.9e-05 52 168 .. 4 111 .. 1 112 [. 0.82 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 3.9e-09 TLD 52 kgptlllvkdkkgkifGaflsqpwksskkffgdgesflFslspkfkvykwtgknkyfiycn......sdglgfGggdpkfslwidsslekgvsrgs 141 +gpt l+k +k+++ + ++ +w++s g++++ + ++ pkf+v+++ + i+ n ++g+++G+ + + ++d+ l+++ FUN_000261-T1 4 HGPTATLIKVGKEELLVVAVDVEWRESSSSWGNSDCRIIQIRPKFQVLRAGPNL---IFFNerarglPSGMVLGQTS-RPCVTMDNALTSAKL--- 92 69******************************************9999997744...444335688899******98.999*******99999... PP TLD 142 ekcetfenpllsgqekfkidevEvWgl 168 + + s ++++EvWg+ FUN_000261-T1 93 HYQANL-----S---PQTVQKIEVWGC 111 332322.....2...234788888887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1645 (0.0643962); expected 510.9 (0.02) Passed bias filter: 867 (0.0339401); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1634.82 // Query: FUN_000262-T1 [L=212] Description: FUN_000262 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (212 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1069 (0.0418477); expected 510.9 (0.02) Passed bias filter: 899 (0.0351928); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2080.24 // Query: FUN_000263-T1 [L=673] Description: FUN_000263 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-199 665.7 8.7 1.2e-199 665.5 8.7 1.0 1 Dymeclin Dyggve-Melchior-Clausen syndrome protein 1.8e-08 33.6 14.6 0.00075 18.3 7.5 3.1 3 Hid1 High-temperature-induced dauer-formation protein ------ inclusion threshold ------ 0.038 14.3 0.1 0.13 12.5 0.1 1.9 2 BAMBI_C BMP and activin membrane-bound inhibitor homolog C- Domain annotation for each model (and alignments): >> Dymeclin Dyggve-Melchior-Clausen syndrome protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 665.5 8.7 1.4e-203 1.2e-199 1 673 [] 1 647 [. 1 647 [. 0.92 Alignments for each domain: == domain 1 score: 665.5 bits; conditional E-value: 1.4e-203 Dymeclin 1 MGassSklkklfrkavlqllsgtqpisaddpfWdqllsfslkeptssqdvflleerlepaseilalrnertgnlatLlrkfverlvelkescssas 96 MGa+ S+ ++l+ + vlq ++g++ + +dd+fWd++l+fs++ p +s+d +llee++ep+++ l+ +n +++n+ tL+++f++r+ +lk++++ + FUN_000263-T1 1 MGAKPSSISDLQHNPVLQIFTGETAVGEDDEFWDDILAFSFQAPYNSADARLLEEATEPICQKLVANNLKSRNFLTLIKVFLKRVPSLKDGTKNDD 96 ******************************************************************************************544444 PP Dymeclin 97 eqeelflwqalNalfllrrilkflveraseeellehfe.......eeeddeeeedeeaseeaqplaesLllalvdllfcpdftvpvtdstyalrle 185 e f+w+ +Na+ l+r + k+++e +ee+ ++f +e+ ++ ++++++ ++ ++e+L+ +l+d+++ +vpv + ty +++e FUN_000263-T1 97 ---EAFMWEMYNAILLVRSFSKYFIEFLPNEEVIKQFGgeavkteGDESVSGFTEQVSHYRDCGVIEELFCELIDVII----NVPVREGTYPIHVE 185 ...57********************************9988886544555555667777788889*************....************** PP Dymeclin 186 llnlLlvllSeqlysppssasksitnplldgacsseaslalplvtsLLntviaydpvps.ladesdagsgvpynhllglvsdlaaslwllltlals 280 ++n+LlvllS+q++ p s ++ +++++l+ + ++ ++lv+ LL+++i+ +++p+ l+ +++g++ s+w+++ +++ FUN_000263-T1 186 AINTLLVLLSVQMFDPRASHNSIFYQVILKR-GGQNCG--HDLVRILLKNFITKEKTPPeLSVANTGGWFS--------------SVWSWFGSQS- 263 ****************666666677777775.444444..7****************66555555555444..............4455554443. PP Dymeclin 281 eseseeskeplaeqslllLlvlldhdkseksvkesssgaeNpfreaLsrlhdsee.......sesds....dfkivfsglfrllnntvpseqtlqf 365 ++ e+ + la+qslllLlvl++h++++k++ Np+r+aL+++ + esd+ f++ + l++++++ + ++qt FUN_000263-T1 264 --SEDEDLSLLANQSLLLLLVLVNHCTQDKQQL-------NPYRHALFSFANRNVkdtvtedGESDKecapPFTLHIGMLYTAICTDLHKDQT--- 347 ..567788**********************966.......***********888777888773444467899*********************... PP Dymeclin 366 hqellllLYkLlhsNskfleyvlsrsdveellvPiLellydaredqsrvghiyilliiLLiLSedrnFnkrlhklilksvpwyterllteislgdL 461 +llLY+Llh+N+++ +++ls++d+++l++PiL+lly+a +++ hiy+ liiLLiLS+d+nFnk++h+l+++s+pwy+er++t i+lg+L FUN_000263-T1 348 ----TLLLYLLLHRNPNVSTFILSKTDIDNLVMPILKLLYNADNHNAH--HIYMSLIILLILSQDDNFNKSVHELTIPSIPWYKERVITNITLGGL 437 ....********************************************..********************************************** PP Dymeclin 462 lilvlirtiqynlqrlrDkyLhtnclaiLaNmSpyfknLsmyaaqrLvsLlellskkraklleeangk......eedekasedlaqelsvleellr 551 l+lv++rtiqyn++++rDkyLhtncla+LaNmS++f+ L++y+ qr+vsL llskk+ak+ e ++ +++e+++ d +l++lee++r FUN_000263-T1 438 LVLVVLRTIQYNMTKMRDKYLHTNCLATLANMSSQFHALHPYVTQRIVSLYALLSKKHAKVMELIKQTegrtsaNTQEGQHTDHLADLAILEEVIR 533 *************************************************************9999888999**99********************* PP Dymeclin 552 lllEilnsiLqyqldgNpnLVYailrkrevFeqlanhpsfqdplqnilrvlqffsprvekicadkgsldvseilkiiqkgtlvgllpvphpkdrlk 647 ++lEi+ns+ ++ l++NpnLVY++l++re+F+q+++hp+f+d++qni++vl+ffs+r+e+ + l+v +l++i++gtl++ p++rlk FUN_000263-T1 534 MVLEIINSCVTNTLHHNPNLVYTLLHRRELFAQFRTHPTFHDIIQNIDTVLSFFSARLEEHPDQ--TLSVGVVLDVIKQGTLKW------PRERLK 621 ************************************************************8887..4*****************......88**** PP Dymeclin 648 kfpelkfkYeeeesteefFipyvwsl 673 kfpelkfkY+eee++eefFipyvwsl FUN_000263-T1 622 KFPELKFKYVEEEQPEEFFIPYVWSL 647 ************************96 PP >> Hid1 High-temperature-induced dauer-formation protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.041 3.5e+02 60 88 .. 71 98 .. 62 119 .. 0.72 2 ! 18.3 7.5 8.8e-08 0.00075 369 520 .. 346 495 .. 340 501 .. 0.86 3 ! 17.6 0.2 1.4e-07 0.0012 530 571 .. 530 571 .. 519 588 .. 0.89 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.041 Hid1 60 leNletLilvlverlialkkdpsfpdeka 88 N+ tLi v ++r+ lk+ ++ +d +a FUN_000263-T1 71 SRNFLTLIKVFLKRVPSLKDGTKNDD-EA 98 57999999999999999988876655.33 PP == domain 2 score: 18.3 bits; conditional E-value: 8.8e-08 Hid1 369 ellvLlwellqcNkrfrsfvidssrvldllvlilYyifeyrsdaskkglvkicvfiLlllsseknfgkrLnkpfeaqetlPtsiripvfkgtyadf 464 +++Ll ll+ N +f++ ++ +l+++il + y +d ++ ++ + ++iLl ls + nf k++ + ++P + + t + FUN_000263-T1 346 QTTLLLYLLLHRNPNVSTFILSKTDIDNLVMPILKL--LYNADNHNAHHIYMSLIILLILSQDDNFNKSVHELTIP--SIPWYKERVITNITLGGL 437 5678999***************99999999999865..588999999*******************9998876665..899666666677899999 PP Hid1 465 liiaihkll..ttskeklselvdaLleilvnlvpylkgLsmaacskllqLleslSsps 520 l++++ + + + +k + + l + l++l n++ + L ++++ L lS++ FUN_000263-T1 438 LVLVVLRTIqyNMTKMRDKYLHTNCLATLANMSSQFHALHPYVTQRIVSLYALLSKKH 495 99888888844556777788999999*************************9999875 PP == domain 3 score: 17.6 bits; conditional E-value: 1.4e-07 Hid1 530 kllallleainniiekqfkknsnLvysilkkrkvfealanlt 571 ++++++le+in+ ++ ++n+nLvy++l r+ f + ++ + FUN_000263-T1 530 EVIRMVLEIINSCVTNTLHHNPNLVYTLLHRRELFAQFRTHP 571 7899*********************************99865 PP >> BAMBI_C BMP and activin membrane-bound inhibitor homolog C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.2 1e+04 36 54 .. 181 199 .. 171 206 .. 0.81 2 ? 12.5 0.1 1.5e-05 0.13 14 81 .. 410 478 .. 403 496 .. 0.84 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.2 BAMBI_C 36 piagglilvllimlalrml 54 pi i +ll++l+++m+ FUN_000263-T1 181 PIHVEAINTLLVLLSVQMF 199 6666778899999999996 PP == domain 2 score: 12.5 bits; conditional E-value: 1.5e-05 BAMBI_C 14 itkvqelasakevwfraaviavpiagg.lilvllimlalrmlrsenkrlrdqrqqalsrlhysfhghha 81 v el+ w++ vi+ gg l+lv+l + m + +k l+ + l+++ fh+ h FUN_000263-T1 410 NKSVHELTIPSIPWYKERVITNITLGGlLVLVVLRTIQYNMTKMRDKYLHTNCLATLANMSSQFHALHP 478 5678999999999******98666666267899999999**************************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (673 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1044 (0.0408691); expected 510.9 (0.02) Passed bias filter: 730 (0.028577); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.37s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6695.64 // Query: FUN_000264-T1 [L=378] Description: FUN_000264 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-40 139.5 0.0 2.9e-40 138.9 0.0 1.3 1 MH2 MH2 domain 5.4e-21 75.2 0.1 1.2e-20 74.1 0.1 1.6 1 MH1 MH1 domain Domain annotation for each model (and alignments): >> MH2 MH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.9 0.0 2.2e-44 2.9e-40 1 172 [. 197 374 .. 197 375 .. 0.87 Alignments for each domain: == domain 1 score: 138.9 bits; conditional E-value: 2.2e-44 MH2 1 eiWckiayyElnervgeafkvsssvsvtvdGstdpsdgerfcLgllsnvnrnek.vekvrkkigkGvklsleeegevwiknlsdspvfVqsptldr 95 ++Wc+iay+E+ner+g +++ +s+v+ ++d +ps+ fcL l+++++ ++ +++vr++ig G++l+ e +e+wi+n+s+ ++f + ptl FUN_000264-T1 197 KHWCSIAYWEHNERIGPTYEGTSDVVNVFDWLPEPSG---FCLADLNRSSDVSEgTKRVRSQIGYGLQLTRE-REEIWIYNRSNFSLFANGPTLTF 288 69*********************95555776666666...********97766449****************.7********************97 PP MH2 96 eagrel.......dtvhklppeeslkvFdlekfaklleqeekavalepvdaelcsvriSfvKgwG.....eeysrqditstPcWleihl 172 ++ + + vhk+pp++slkvFd++ +++++ ++ +++e s+riSf KgwG ++y r +ts+PcW+eihl FUN_000264-T1 289 SNVNIPggklrhnIVVHKVPPGCSLKVFDYKLTPQVCRA-IDSEGVRCYHPE--SIRISFKKGWGsttssKKYCRPLVTSCPCWIEIHL 374 766666788888789******99*******999999988.555555666678..***********777777899**************8 PP >> MH1 MH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.1 0.1 9.2e-25 1.2e-20 2 102 .. 36 130 .. 35 131 .. 0.92 Alignments for each domain: == domain 1 score: 74.1 bits; conditional E-value: 9.2e-25 MH1 2 kkavesLlkklkkkkeeleelleaveskgkkktkCvliprsldgrlqvaqrkglphvilcrlfrwpdlqskselkaletcesaeeskkeevCvnPy 97 ++ ++s+lk+lk++ ++ +l++a+e++g+++t C+ i++ + rl+ ++ +ph++l r+fr+p+++s+selk+ +c s++ + ++vC+nPy FUN_000264-T1 36 EALTHSILKRLKDS--DFAALVQALETQGGCETPCIFIHS--HERLE-KRVAVEPHLVLFRIFRLPQIKSSSELKHNASCLSSYGL-DKNVCINPY 125 57799********9..5**********************4..68888.77889******************************999.678****** PP MH1 98 Hysrv 102 Hys v FUN_000264-T1 126 HYSAV 130 **987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (378 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 500 (0.0195733); expected 510.9 (0.02) Passed bias filter: 456 (0.0178509); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3650.22 // Query: FUN_000265-T1 [L=420] Description: FUN_000265 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-67 225.8 0.1 7.8e-67 225.4 0.1 1.2 1 MH2 MH2 domain 3.1e-41 140.3 0.2 6e-41 139.3 0.2 1.5 1 MH1 MH1 domain 0.0078 16.5 0.0 0.014 15.6 0.0 1.4 1 IRF-3 Interferon-regulatory factor 3 Domain annotation for each model (and alignments): >> MH2 MH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 225.4 0.1 9.1e-71 7.8e-67 2 173 .] 226 396 .. 225 396 .. 0.93 Alignments for each domain: == domain 1 score: 225.4 bits; conditional E-value: 9.1e-71 MH2 2 iWckiayyElnervgeafkvsssvsvtvdGstdpsdgerfcLgllsnvnrnekvekvrkkigkGvklsleeegevwiknlsdspvfVqsptldrea 97 +Wc+i+yyE+n+rvge f ++++ s+tvdG+tdps+++rfcLgllsn+nrn+++e +rk+igkGv+l++ +gev++++lsds++fVqsp+++++ FUN_000265-T1 226 HWCQISYYEMNTRVGESFYAAKP-SLTVDGFTDPSGSDRFCLGLLSNINRNPQIEMTRKHIGKGVRLYYI-GGEVFAECLSDSSIFVQSPNCNQRY 319 8*********************6.**********************************************.7************************ PP MH2 98 greldtvhklppeeslkvFdlekfaklleqeekavalepvd.aelcsvriSfvKgwGeeysrqditstPcWleihlh 173 g++++tv+k+pp+++lk+F++++fa+ll+q+ ++ ++ ++ +++c++r+SfvKgwG+ey+rq++tstPcW+e+hl+ FUN_000265-T1 320 GWHPATVCKIPPGCNLKIFNNQEFAQLLSQSVNQGFEAVYAlTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 396 ************99****************44443333333245*******************************97 PP >> MH1 MH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 139.3 0.2 7.1e-45 6e-41 2 103 .] 30 129 .. 29 129 .. 0.97 Alignments for each domain: == domain 1 score: 139.3 bits; conditional E-value: 7.1e-45 MH1 2 kkavesLlkklkkkkeeleelleaveskgkkktkCvliprsldgrlqvaqrkglphvilcrlfrwpdlqskselkaletcesaeeskkeevCvnPy 97 +kav+sL+kklkk+ leel++a++ + + +tkCv+iprsldgrlqv++rkglphvi+crl+rwpdlqs++el+++e+c++a+++kk+evCvnP+ FUN_000265-T1 30 EKAVKSLVKKLKKT-GGLEELERAIT-NPGIPTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLQSHHELRPIESCDYAFSLKKDEVCVNPF 123 89************.6**********.889****************************************************************** PP MH1 98 Hysrvv 103 Hy+rv+ FUN_000265-T1 124 HYQRVE 129 ****95 PP >> IRF-3 Interferon-regulatory factor 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 1.6e-06 0.014 60 139 .. 276 357 .. 240 385 .. 0.79 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.6e-06 IRF-3 60 kqreytkklLsvlerGllLevsgqglyakRLcqsrVfwsgpealekd..kPn...kLerekevklfdlekFlreLiqfqkgsgrs 139 q+e+t+ +++ +G+ L + g +++a+ L s +f+++p+ ++ +P k++ + k+f+ ++F + L q ++ ++ FUN_000265-T1 276 PQIEMTR---KHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYgwHPAtvcKIPPGCNLKIFNNQEFAQLLSQSVNQGFEA 357 4555555...69999************************99877766685543449****************9998877765554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (420 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 742 (0.0290468); expected 510.9 (0.02) Passed bias filter: 669 (0.0261891); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.46 # Mc/sec: 3716.13 // Query: FUN_000266-T1 [L=190] Description: FUN_000266 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-17 62.5 41.7 7.3e-06 26.9 8.4 3.4 3 ShK ShK domain-like ------ inclusion threshold ------ 0.22 11.4 0.1 32 4.3 0.0 2.8 3 Cas8b_N Type I-B CRISPR Cas8b N-terminal domain 0.61 10.5 18.2 6.4 7.2 0.5 4.5 4 Zn_ribbon_tTFIIB Transcription factor IIB, zinc ribbon, Tryp 0.91 10.1 20.6 0.2 12.2 3.8 3.7 3 EGF_Sp38_C Zona-pellucida-binding protein (Sp38) C-ter Domain annotation for each model (and alignments): >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 9.5 3e-09 1.9e-05 2 37 .] 44 82 .. 43 82 .. 0.87 2 ! 26.9 8.4 1.1e-09 7.3e-06 2 37 .] 95 133 .. 94 133 .. 0.84 3 ! 22.4 7.8 3e-08 0.00019 2 37 .] 146 184 .. 145 184 .. 0.79 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 3e-09 ShK 2 Cv.Dps..sdCaswaang..CnspayqdfmkenCpktCgfC 37 Cv D++ C++ aa+ C+ dfm++nCpk+CgfC FUN_000266-T1 44 CVdDKNyaDKCPEKAAIKdyCKYHS--DFMQKNCPKSCGFC 82 887555669******99999*8877..************** PP == domain 2 score: 26.9 bits; conditional E-value: 1.1e-09 ShK 2 Cv...DpssdCaswaang..CnspayqdfmkenCpktCgfC 37 C ++ C++ aa+ C++ dfm++nCpk+CgfC FUN_000266-T1 95 CAddeNYADKCPEKAAIKdyCKHHS--DFMQKNCPKSCGFC 133 66533445999999999999*9988..************** PP == domain 3 score: 22.4 bits; conditional E-value: 3e-08 ShK 2 Cv.Dps..sdCaswaang..CnspayqdfmkenCpktCgfC 37 C D++ C++ aa+ C+ y +fm++nCp++CgfC FUN_000266-T1 146 CIdDANyaDACPEKAAIPnyCQ--MYAAFMRKNCPYSCGFC 184 6653334488999999877896..588************** PP >> Cas8b_N Type I-B CRISPR Cas8b N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.039 2.5e+02 201 233 .. 48 80 .. 35 87 .. 0.82 2 ? 2.5 0.0 0.018 1.1e+02 201 232 .. 99 130 .. 81 138 .. 0.82 3 ? 4.3 0.0 0.005 32 200 227 .. 149 176 .. 141 188 .. 0.86 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.039 Cas8b_N 201 vgYvlaiPdvadLevFceelpklLksreteksg 233 Y+ P+ a+++ +c+ +++++ +++ g FUN_000266-T1 48 KNYADKCPEKAAIKDYCKYHSDFMQKNCPKSCG 80 5678889***************99988666655 PP == domain 2 score: 2.5 bits; conditional E-value: 0.018 Cas8b_N 201 vgYvlaiPdvadLevFceelpklLksreteks 232 Y+ P+ a+++ +c++ +++++ +++ FUN_000266-T1 99 ENYADKCPEKAAIKDYCKHHSDFMQKNCPKSC 130 5678889*****************98866655 PP == domain 3 score: 4.3 bits; conditional E-value: 0.005 Cas8b_N 200 evgYvlaiPdvadLevFceelpklLksr 227 ++ Y+ a P+ a++ +c+ +++++++ FUN_000266-T1 149 DANYADACPEKAAIPNYCQMYAAFMRKN 176 678999******************9986 PP >> Zn_ribbon_tTFIIB Transcription factor IIB, zinc ribbon, Trypanosome # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.5 0.001 6.4 5 16 .. 68 80 .. 66 86 .. 0.78 2 ? 6.8 0.9 0.0014 9 5 16 .. 119 131 .. 117 136 .. 0.78 3 ? -3.1 0.1 1.7 1.1e+04 24 36 .. 148 160 .. 147 162 .. 0.54 4 ? 6.6 0.8 0.0016 10 6 16 .. 171 182 .. 168 188 .. 0.78 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.001 Zn_ribbon_tTFIIB 5 aDfvGknCPy.Cg 16 +Df+ knCP Cg FUN_000266-T1 68 SDFMQKNCPKsCG 80 7********5366 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0014 Zn_ribbon_tTFIIB 5 aDfvGknCPy.Cg 16 +Df+ knCP Cg FUN_000266-T1 119 SDFMQKNCPKsCG 131 7********5366 PP == domain 3 score: -3.1 bits; conditional E-value: 1.7 Zn_ribbon_tTFIIB 24 DdalGEvACteCA 36 Dda AC e A FUN_000266-T1 148 DDANYADACPEKA 160 5555555666544 PP == domain 4 score: 6.6 bits; conditional E-value: 0.0016 Zn_ribbon_tTFIIB 6 DfvGknCPy.Cg 16 f+ knCPy Cg FUN_000266-T1 171 AFMRKNCPYsCG 182 5999*****777 PP >> EGF_Sp38_C Zona-pellucida-binding protein (Sp38) C-terminal EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 1.7 0.0053 34 12 35 .. 72 95 .. 66 102 .. 0.84 2 ? 12.2 3.8 3.2e-05 0.2 12 36 .. 123 147 .. 116 157 .. 0.89 3 ? 2.7 0.9 0.029 1.8e+02 12 24 .. 174 186 .. 163 188 .. 0.84 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0053 EGF_Sp38_C 12 HsnCaeCCvvCsPgtyspdsgvtC 35 +nC++ C Cs p v C FUN_000266-T1 72 QKNCPKSCGFCSSEIKKPPAPVVC 95 689*********988888877777 PP == domain 2 score: 12.2 bits; conditional E-value: 3.2e-05 EGF_Sp38_C 12 HsnCaeCCvvCsPgtyspdsgvtCl 36 +nC++ C Cs g++ p s + C FUN_000266-T1 123 QKNCPKSCGFCSSGSFKPPSPIGCI 147 689******************9995 PP == domain 3 score: 2.7 bits; conditional E-value: 0.029 EGF_Sp38_C 12 HsnCaeCCvvCsP 24 +nC+ C Cs FUN_000266-T1 174 RKNCPYSCGFCSS 186 689********96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (190 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 765 (0.0299472); expected 510.9 (0.02) Passed bias filter: 308 (0.0120572); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.48 # Mc/sec: 1591.97 // Query: FUN_000267-T1 [L=190] Description: FUN_000267 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-19 69.7 31.6 2.3e-06 28.5 4.5 3.4 3 ShK ShK domain-like ------ inclusion threshold ------ 3 8.4 13.7 4.5 7.8 0.3 4.5 4 zf-CCCH Zinc finger C-x8-C-x5-C-x3-H type (and similar) 7.4 7.7 29.0 10 7.3 11.7 3.6 3 Crisp Crisp Domain annotation for each model (and alignments): >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 3.7 3.8e-10 3.3e-06 7 36 .. 52 82 .. 43 82 .. 0.92 2 ! 25.3 7.7 2.8e-09 2.4e-05 2 37 .] 103 141 .. 102 141 .. 0.97 3 ! 28.5 4.5 2.8e-10 2.3e-06 1 37 [] 148 187 .. 148 187 .. 0.94 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 3.8e-10 ShK 7 sdCaswaang.CnspayqdfmkenCpktCgf 36 C++wa++g C++ fm +C+k+C++ FUN_000267-T1 52 HRCPKWAQQGlCEDEMKTRFMEHYCRKSCKL 82 57***************************85 PP == domain 2 score: 25.3 bits; conditional E-value: 2.8e-09 ShK 2 CvDpssdCaswaang.Cnspa..yqdfmkenCpktCgfC 37 C D++++C+ w+++g C+s++ ++ + +C tC C FUN_000267-T1 103 CIDYDINCDRWKSMGaCQSNNvnIKSPLNVYCGVTCDAC 141 ******************999899*************99 PP == domain 3 score: 28.5 bits; conditional E-value: 2.8e-10 ShK 1 sCvDpssdCaswaang.Cnspa..yqdfmkenCpktCgfC 37 +C D++ +C + ++ g Cns+ q +k++C tCgfC FUN_000267-T1 148 ECHDKRANCKELKREGfCNSTDpiVQYEVKSYCVVTCGFC 187 5******************9998778889*********** PP >> zf-CCCH Zinc finger C-x8-C-x5-C-x3-H type (and similar) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.02 1.7e+02 5 15 .. 53 63 .. 53 64 .. 0.93 2 ? -0.3 1.0 0.19 1.6e+03 8 16 .. 70 77 .. 69 81 .. 0.80 3 ? 4.0 0.1 0.0083 70 5 16 .. 109 120 .. 107 120 .. 0.93 4 ? 7.8 0.3 0.00053 4.5 1 16 [. 151 166 .. 151 166 .. 0.93 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.02 zf-CCCH 5 lCrfflrtGyC 15 +C+ +++ G C FUN_000267-T1 53 RCPKWAQQGLC 63 5********99 PP == domain 2 score: -0.3 bits; conditional E-value: 0.19 zf-CCCH 8 fflrtGyCk 16 +f++ +yC+ FUN_000267-T1 70 RFME-HYCR 77 7999.9**8 PP == domain 3 score: 4.0 bits; conditional E-value: 0.0083 zf-CCCH 5 lCrfflrtGyCk 16 +C++++ +G+C+ FUN_000267-T1 109 NCDRWKSMGACQ 120 7**********7 PP == domain 4 score: 7.8 bits; conditional E-value: 0.00053 zf-CCCH 1 yktelCrfflrtGyCk 16 +k+++C+ +r G+C+ FUN_000267-T1 151 DKRANCKELKREGFCN 166 59*************6 PP >> Crisp Crisp # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 3.7 0.02 1.7e+02 25 49 .. 53 81 .. 41 87 .. 0.67 2 ? 4.1 4.8 0.012 1e+02 21 49 .. 105 139 .. 100 144 .. 0.83 3 ? 7.3 11.7 0.0012 10 4 48 .. 134 184 .. 131 188 .. 0.85 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.02 Crisp 25 nCkelkktlgCenelv....kknCkAsCk 49 C++ +++ Ce+e+ ++ C+ sCk FUN_000267-T1 53 RCPKWAQQGLCEDEMKtrfmEHYCRKSCK 81 57777777777765544444777777776 PP == domain 2 score: 4.1 bits; conditional E-value: 0.012 Crisp 21 dkysnCkelkktlgCenelv......kknCkAsCk 49 d nC++ k++ C++++v + C +C FUN_000267-T1 105 DYDINCDRWKSMGACQSNNVniksplNVYCGVTCD 139 6668**************99888888889999995 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0012 Crisp 4 CpnnCedkLCtnpCeyedkysnCkelkktlgCenelv......kknCkAsC 48 C C+ np e +dk +nCkelk++ C+++ k+ C +C FUN_000267-T1 134 CGVTCDACKAPNPAECHDKRANCKELKREGFCNSTDPivqyevKSYCVVTC 184 77778777778**********************987666777799999999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (190 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 941 (0.036837); expected 510.9 (0.02) Passed bias filter: 365 (0.0142885); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.82s 00:00:01.12 Elapsed: 00:00:00.51 # Mc/sec: 1508.35 // Query: FUN_000268-T1 [L=178] Description: FUN_000268 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.3e-14 52.5 38.8 0.00013 22.9 7.5 3.9 3 ShK ShK domain-like Domain annotation for each model (and alignments): >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 7.5 5.2e-09 0.00013 7 36 .. 40 69 .. 22 69 .. 0.91 2 ! 20.3 6.0 3.4e-08 0.00087 2 37 .] 90 120 .. 89 120 .. 0.98 3 ! 20.6 8.9 2.8e-08 0.00071 2 37 .] 128 167 .. 127 167 .. 0.91 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 5.2e-09 ShK 7 sdCaswaang.CnspayqdfmkenCpktCgf 36 C+++a+ g Cn +a q +m +C+k+Cg+ FUN_000268-T1 40 DRCPEFAREGyCNGSA-QRWMEHYCRKSCGL 69 68***********999.************96 PP == domain 2 score: 20.3 bits; conditional E-value: 3.4e-08 ShK 2 CvDpssdCaswaang.CnspayqdfmkenCpktCgfC 37 C D+++ Ca+ +++g C ++ke+C tC+ C FUN_000268-T1 90 CRDRDIKCAERKQLGqC------GLFKEFCGVTCKSC 120 *****************......9************9 PP == domain 3 score: 20.6 bits; conditional E-value: 2.8e-08 ShK 2 Cv.DpssdCaswaang.Cnspa..yqdfmkenCpktCgfC 37 C D+ dC + +ng C s++ + +mk+nC tC++C FUN_000268-T1 128 CNkDAALDCKMREKNGeCDSTNpkIEYYMKKNCVGTCKYC 167 8889**************96665699************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 863 (0.0337835); expected 510.9 (0.02) Passed bias filter: 275 (0.0107653); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1759.85 // Query: FUN_000269-T1 [L=133] Description: FUN_000269 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00026 22.0 12.7 0.00081 20.4 12.7 1.8 1 ShK ShK domain-like ------ inclusion threshold ------ 0.19 12.1 0.1 0.3 11.4 0.1 1.3 1 L27_1 L27_1 1.3 10.1 12.5 2.7 9.1 12.5 1.5 1 Crisp Crisp Domain annotation for each model (and alignments): >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 12.7 9.5e-08 0.00081 2 37 .] 80 119 .. 67 119 .. 0.92 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 9.5e-08 ShK 2 Cv.DpssdCaswaang.Cnspa..yqdfmkenCpktCgfC 37 C D+ sdC + +ng C s++ + +m++nC tC++C FUN_000269-T1 80 CNkDAASDCKEREKNGeCDSSNpkIEYYMRKNCVATCKYC 119 77899*************976667999************* PP >> L27_1 L27_1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 3.5e-05 0.3 17 42 .. 38 63 .. 31 70 .. 0.89 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 3.5e-05 L27_1 17 LsrpedeeLRtaiekvisiFksnLfq 42 Ls+ +++++R+++ekv +F Lf+ FUN_000269-T1 38 LSSEKSDQVRSNMEKVFIVFLGVLFS 63 8999********************97 PP >> Crisp Crisp # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 12.5 0.00031 2.7 8 49 .. 71 117 .. 67 121 .. 0.74 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00031 Crisp 8 CedkLCtnpCeyedkysnCkelkktlgCenelv......kknCkAsCk 49 C++ C +d+ s+Cke +k+ +C++++ +knC A+Ck FUN_000269-T1 71 CTNAADDSEC-NKDAASDCKEREKNGECDSSNPkieyymRKNCVATCK 117 3333333334.479***************9876677888********8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (133 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 914 (0.03578); expected 510.9 (0.02) Passed bias filter: 474 (0.0185555); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1366.00 // Query: FUN_000270-T1 [L=378] Description: FUN_000270 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-71 237.2 3.7 1.9e-25 88.9 0.1 3.1 3 Mito_carr Mitochondrial carrier protein ------ inclusion threshold ------ 0.078 12.5 0.0 0.7 9.4 0.0 2.2 2 SLC25_like Mitochondrial SLC25 homolog Domain annotation for each model (and alignments): >> Mito_carr Mitochondrial carrier protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.1 0.1 1.5e-25 1.9e-21 4 94 .. 84 172 .. 82 174 .. 0.95 2 ! 88.9 0.1 1.5e-29 1.9e-25 3 94 .. 180 268 .. 178 270 .. 0.94 3 ! 72.4 0.1 2.1e-24 2.6e-20 2 95 .. 275 371 .. 274 372 .. 0.94 Alignments for each domain: == domain 1 score: 76.1 bits; conditional E-value: 1.5e-25 Mito_carr 4 sflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklllk 94 ++++sl aG++aga+ak++++Pld+ K+ +q++++ + k ++ +++k++ e+G+ gl++G++++++r++p+a+++f++ e++k ll++ FUN_000270-T1 84 EVISSLSAGAVAGAVAKTTIAPLDRTKIIFQTSNEPFSVKG--AVGVLQKTYLENGFLGLFRGNSATMARIIPYASLQFTAHEQFKILLRT 172 57899*******************************99877..9******************************************99976 PP == domain 2 score: 88.9 bits; conditional E-value: 1.5e-29 Mito_carr 3 lsflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklllk 94 l++++++laG++ag++a+++tyPld+++ rl +++k++ + + +++ ki+keeG+ + y+Gl+p+l++++p+a+i+f+tye+lkkl+++ FUN_000270-T1 180 LPPVRRFLAGSLAGITAASFTYPLDMIRARLAITQKNKYTG---LANIVVKIYKEEGFPAYYRGLIPTLIGIIPYAGISFFTYESLKKLYFD 268 7899*****************************99997653...9*******************************************9875 PP == domain 3 score: 72.4 bits; conditional E-value: 2.1e-24 Mito_carr 2 elsflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk..ildafkkivkeeGi.rglykGllpnllrvapaaaikfatyetlkklllk 94 +l++l++l+ G++ag+++++vtyPl++++ r+q+++ ++ +k ++ +++++k ++k+eG+ +g ykGl++n+++ +a +++f+t++ l+ +++k FUN_000270-T1 275 KLNPLHRLFFGACAGLLGQSVTYPLEIIRRRMQTNGISGPAKPEYrrMWSTAKYVYKTEGVrKGIYKGLTMNWVKGPVAVGVSFTTFDLLHGFFQK 370 67899*******************************99988777789**************889****************************9987 PP Mito_carr 95 k 95 + FUN_000270-T1 371 R 371 5 PP >> SLC25_like Mitochondrial SLC25 homolog # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.037 4.8e+02 180 200 .. 83 103 .. 47 110 .. 0.72 2 ? 9.4 0.0 5.5e-05 0.7 184 205 .. 184 205 .. 181 225 .. 0.85 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.037 SLC25_like 180 dklykkllaGalsGviAalfs 200 +++ l aGa++G++A + FUN_000270-T1 83 KEVISSLSAGAVAGAVAKTTI 103 367788999******997654 PP == domain 2 score: 9.4 bits; conditional E-value: 5.5e-05 SLC25_like 184 kkllaGalsGviAalfsyifna 205 +++laG l+G++Aa f+y++ FUN_000270-T1 184 RRFLAGSLAGITAASFTYPLDM 205 789****************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (378 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 633 (0.0247798); expected 510.9 (0.02) Passed bias filter: 603 (0.0236054); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3796.04 // Query: FUN_000271-T1 [L=688] Description: FUN_000271 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.8 9.3 6.2 1.3 9.9 2.1 2.6 2 Exo70_N Exocyst complex component Exo70 N-terminal 4 8.4 5.8 5.9 7.9 0.1 2.7 2 DUF8204 Domain of unknown function (DUF8204) Domain annotation for each model (and alignments): >> Exo70_N Exocyst complex component Exo70 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.2 0.2 2.5e+03 30 74 .. 189 233 .. 181 264 .. 0.59 2 ? 9.9 2.1 9.8e-05 1.3 23 61 .. 266 302 .. 260 327 .. 0.80 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.2 Exo70_N 30 lkeYLdavdrlqkaleflkssnlksnska.......lnraqsLlqiAmsrLe 74 lke++d ++l+++ e+ + + l+++++ l + + Le FUN_000271-T1 189 LKEFVDLQNQLKSLEEKSAGN-------NygmkhtrLVELHKNLNASHEILE 233 444444444444444444444.......222233335555544444444444 PP == domain 2 score: 9.9 bits; conditional E-value: 9.8e-05 Exo70_N 23 rkgpekelkeYLdavdrlqkaleflkssnlksnskalnr 61 +++ +ke +eYLdav++ + a ++++ nlks+ k+l + FUN_000271-T1 266 NADYQKEQNEYLDAVNKQEIAQQEFE--NLKSQYKKLYN 302 55778899******************..99999999533 PP >> DUF8204 Domain of unknown function (DUF8204) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 1.8 0.046 5.9e+02 1 51 [. 74 125 .. 74 131 .. 0.76 2 ? 7.9 0.1 0.00046 5.9 21 82 .. 215 275 .. 202 280 .. 0.86 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.046 DUF8204 1 kgksckGclyyssalksksknplcv.gisrslqqvpssivgeseleaskegr 51 k ks G ss+ ks+++ p g + ++ +++++ ++ +e ++e + FUN_000271-T1 74 KSKSSSGSSSRSSSAKSQKSRPETSpGGNDVSPTTNEQVIAKEATEQQHEMQ 125 67999999999*******9999865266666677777777777777776654 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00046 DUF8204 21 nplcvgisrslqqvpssivgeseleaskegrslsdfkYaCvGysvyldkkdssadkqekqae 82 +++ v + + l+ +++i+++ +++++ke +++ df+ a s+++++ + +ad q++q e FUN_000271-T1 215 HTRLVELHKNLN-ASHEILEKLKAQTAKEYQDVVDFNAAFNMRSMFINQAQMNADYQKEQNE 275 556667777776.688999*******************************999999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (688 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3286 (0.128636); expected 510.9 (0.02) Passed bias filter: 486 (0.0190252); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.44u 0.44s 00:00:00.88 Elapsed: 00:00:00.49 # Mc/sec: 5710.21 // Query: FUN_000271-T2 [L=675] Description: FUN_000271 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.5 9.6 6.0 1.2 9.9 2.1 2.6 2 Exo70_N Exocyst complex component Exo70 N-terminal 3.9 8.4 5.8 5.7 7.9 0.1 2.7 2 DUF8204 Domain of unknown function (DUF8204) Domain annotation for each model (and alignments): >> Exo70_N Exocyst complex component Exo70 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 0.22 2.8e+03 30 74 .. 176 220 .. 170 235 .. 0.52 2 ? 9.9 2.1 9.7e-05 1.2 23 61 .. 253 289 .. 247 314 .. 0.80 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.22 Exo70_N 30 lkeYLdavdrlqkaleflkssnlksnska.......lnraqsLlqiAmsrLe 74 lke++d ++l+++ e+ + + l+++++ l + + Le FUN_000271-T2 176 LKEFVDLQNQLKSLEEKSAGN-------NygmkhtrLVELHKNLNASHEILE 220 444444444444444444444.......233333335555555544444444 PP == domain 2 score: 9.9 bits; conditional E-value: 9.7e-05 Exo70_N 23 rkgpekelkeYLdavdrlqkaleflkssnlksnskalnr 61 +++ +ke +eYLdav++ + a ++++ nlks+ k+l + FUN_000271-T2 253 NADYQKEQNEYLDAVNKQEIAQQEFE--NLKSQYKKLYN 289 55778899******************..99999999533 PP >> DUF8204 Domain of unknown function (DUF8204) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 1.8 0.045 5.8e+02 1 51 [. 61 112 .. 61 118 .. 0.76 2 ? 7.9 0.1 0.00045 5.7 21 82 .. 202 262 .. 189 267 .. 0.86 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.045 DUF8204 1 kgksckGclyyssalksksknplcv.gisrslqqvpssivgeseleaskegr 51 k ks G ss+ ks+++ p g + ++ +++++ ++ +e ++e + FUN_000271-T2 61 KSKSSSGSSSRSSSAKSQKSRPETSpGGNDVSPTTNEQVIAKEATEQQHEMQ 112 67999999999*******9999865266666677777777777777776654 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00045 DUF8204 21 nplcvgisrslqqvpssivgeseleaskegrslsdfkYaCvGysvyldkkdssadkqekqae 82 +++ v + + l+ +++i+++ +++++ke +++ df+ a s+++++ + +ad q++q e FUN_000271-T2 202 HTRLVELHKNLN-ASHEILEKLKAQTAKEYQDVVDFNAAFNMRSMFINQAQMNADYQKEQNE 262 556667777776.688999*******************************999999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (675 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4134 (0.161832); expected 510.9 (0.02) Passed bias filter: 702 (0.0274809); expected 510.9 (0.02) Passed Vit filter: 89 (0.00348405); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.51u 0.40s 00:00:00.91 Elapsed: 00:00:00.44 # Mc/sec: 6218.85 // Query: FUN_000272-T1 [L=203] Description: FUN_000272 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0033 17.9 1.5 0.0077 16.7 1.5 1.5 1 Nucleoprot-TPR Nucleoprotein TPR-like domain 0.01 15.6 0.2 0.014 15.1 0.2 1.2 1 PUL PUL domain ------ inclusion threshold ------ 0.16 12.8 0.0 0.3 11.9 0.0 1.4 1 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain Domain annotation for each model (and alignments): >> Nucleoprot-TPR Nucleoprotein TPR-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 1.5 9.1e-07 0.0077 31 70 .. 4 43 .. 2 50 .. 0.92 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 9.1e-07 Nucleoprot-TPR 31 LkaKteellklrrekgeeileLqakledkeeeleelsssl 70 Lk+K+++ll+ + ++ee ++L+++l + ++++ ++s+ + FUN_000272-T1 4 LKKKNDSLLEDSERHTEEKYKLKCQLLETNQQMGDQSEYC 43 9********************************9998765 PP >> PUL PUL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.2 1.7e-06 0.014 84 192 .. 54 170 .. 54 200 .. 0.67 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.7e-06 PUL 84 LlRllaldprvaaylaeeegg...ktissllslltssslssap..kslenn.rmlalRllaNlFssplgrellls..efeeilstlasllssslls 171 L+R++ +++ ++ l ++ + ++ s+ ++++ ++ +++a+ s e + ++ + +++N+ + ++gr+ l+s + +++++++++l s+ + FUN_000272-T1 54 LWRVSRQQESITSLLGGNKADeflQITSRTVESYFETYSEDATkeTSDECQfVLALTGTVTNMAAAAEGRDFLVSreSGLALIDSFITVLCVSTVD 149 67777777777775554444477744444444444444443331133333456777789***************977777888888888888888* PP PUL 172 snknlrialatlllNlavllh 192 +n lr +l+N+++ ++ FUN_000272-T1 150 KNVKLRNLMLMALYNISINFS 170 *****************9885 PP >> Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 3.6e-05 0.3 5 33 .. 164 192 .. 162 196 .. 0.90 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.6e-05 Ribosomal_TL5_C 5 eVpvhlvGeapgvkkggvleqvlreveve 33 ++ +++ G +kkgg++e+ +++++ve FUN_000272-T1 164 NISINFSGMQYIMKKGGIMEHLIHTIKVE 192 68999***88899***************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1321 (0.0517127); expected 510.9 (0.02) Passed bias filter: 783 (0.0306518); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2041.95 // Query: FUN_000273-T1 [L=147] Description: FUN_000273 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.025 15.5 17.8 0.11 13.5 17.8 2.0 1 UPAR_LY6 u-PAR/Ly-6 domain 0.058 13.7 0.2 0.08 13.3 0.2 1.2 1 Lipocalin_5 Lipocalin-like domain 0.26 12.8 12.4 0.43 12.1 12.4 1.4 1 Activin_recp Activin types I and II receptor domain 0.63 11.6 12.6 0.82 11.2 12.6 1.2 1 QVR Quiver family u-PAR/Ly-6-like domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 17.8 1.7e-05 0.11 2 81 .. 27 122 .. 26 123 .. 0.80 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.7e-05 UPAR_LY6 2 glrCysClgessssccssgs........sCpkgd...tqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCns 81 +lrC++C+g + + +++++ +Cpk d +C + + ++++g ++++ + C +++c + + ++ ccq+dlCn+ FUN_000273-T1 27 TLRCFHCKGSDDGRPYPQSTcedeqsevTCPKYDnvsMVCGKYHHQIQSGVMMHEVEGRACvpQSHCHWIGMSCRAIlmaGGDCQYACCQGDLCNN 122 79******9986554444422222257788665556679****************************999888777667778*************7 PP >> Lipocalin_5 Lipocalin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.2 1.2e-05 0.08 45 96 .. 37 87 .. 29 99 .. 0.82 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.2e-05 Lipocalin_5 45 ssertplsveaveqaskeelaealksyvayaGryslkdeskvvthhvevslv 96 + +r++ ++++ e++++e + ++++ +++G+y+ + s+v+ h ve+ + FUN_000273-T1 37 DDGRPY-PQSTCEDEQSEVTCPKYDNVSMVCGKYHHQIQSGVMMHEVEGRAC 87 556665.7788899999999**************8888888*******9655 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 12.4 6.8e-05 0.43 2 78 .. 29 123 .. 28 124 .. 0.65 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 6.8e-05 Activin_recp 2 kCy.Cetsk.........CeedesnvtcetdgsCfssvekettgkikvvkkgclsreqdpleCktsnkpeqlns............rieCCktdfC 75 +C+ C++s+ Ce+++s+vtc + v+ + + ++++++g +++e + C++++ + + + CC++d+C FUN_000273-T1 29 RCFhCKGSDdgrpypqstCEDEQSEVTCPKY----DNVSMVCGKYHHQIQSGVMMHEVEGRACVPQSHCHWIGMscrailmaggdcQYACCQGDLC 120 7855887766655555667777777777664....555553444444788888888866666666666666555666666777777********** PP Activin_recp 76 Nkn 78 N++ FUN_000273-T1 121 NNA 123 *96 PP >> QVR Quiver family u-PAR/Ly-6-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 12.6 0.00013 0.82 1 86 [] 28 121 .. 28 121 .. 0.77 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00013 QVR 1 lkCYqCnse......edpeCedefdekevelkeCse...eatvCvkivek...eeegeerviRgC.eseseedeeegckeessekkkleeCtCktd 83 l+C++C+ + ++ + e+e++ ++C++ + vC k+ ++ + +e+ R C +++ + +c+ +++ ++ +C++d FUN_000273-T1 28 LRCFHCKGSddgrpyPQS-----TCEDEQSEVTCPKydnVSMVCGKYHHQiqsGVMMHEVEGRACvPQSHCHWIGMSCRAILMAGGDCQYACCQGD 118 79*****99444444444.....4455777888888776789*****999766666677778***444455667899*************9***** PP QVR 84 lCN 86 lCN FUN_000273-T1 119 LCN 121 *** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (147 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 846 (0.033118); expected 510.9 (0.02) Passed bias filter: 328 (0.0128401); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.41 # Mc/sec: 1440.34 // Query: FUN_000274-T1 [L=211] Description: FUN_000274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-31 110.2 0.0 1.5e-31 109.8 0.0 1.2 1 MAM MAM domain, meprin/A5/mu 1.3e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 Astacin Astacin (Peptidase family M12A) ------ inclusion threshold ------ 0.022 14.1 0.0 0.023 14.1 0.0 1.1 1 EP400_N E1A-binding protein p400, N-terminal Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.8 0.0 1.8e-35 1.5e-31 1 157 [. 66 211 .] 66 211 .] 0.94 Alignments for each domain: == domain 1 score: 109.8 bits; conditional E-value: 1.8e-35 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvll 93 C+F++g +Cg++qd++d++dW+r++++ s++tgp dh+ g+G+y+++etss + g+ ++s+ ++ + k +Cl+F+yhm+gs+ gtlrv l FUN_000274-T1 66 CNFNNG-MCGFIQDQDDQFDWTRKKGQtqSSNTGPLGDHN--GEGYYVYIETSSPrRLGD-KAIISRRVSLTGK-SCLSFFYHMRGSGMGTLRVKL 156 ******.******************99999**********..************955555.6688999999999.9******************99 PP MAM 94 reegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 + ++++ sg+qg+ W ++e+ l+ + +++fe++rg++ +gd a+Dd+ + ++C FUN_000274-T1 157 CD------AVIFEKSGNQGSIWLKQELRLQG-SGTKKLIFEGIRGRNFRGDAAIDDVMI--YDC 211 64......5899*******************.*************************98..555 PP >> Astacin Astacin (Peptidase family M12A) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.9 0.0 2.6e-10 2.2e-06 141 186 .] 1 43 [. 1 43 [. 0.95 Alignments for each domain: == domain 1 score: 27.9 bits; conditional E-value: 2.6e-10 Astacin 141 mhYakkafskngaleTivpkkeelqktiGqreklsevDikkinklY 186 mhY+++afskng ++Ti+pk+ tiG+r+ ls +D++++ lY FUN_000274-T1 1 MHYRANAFSKNG-QPTIIPKRA--GVTIGNRRALSPIDVQQMMLLY 43 9*********99.8******99..78****************9888 PP >> EP400_N E1A-binding protein p400, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.0 2.6e-06 0.023 155 219 .. 106 171 .. 11 186 .. 0.74 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.6e-06 EP400_N 155 patalGlcgqsptrfvdasllvrqislgsssggghfvyqdGtglaqlasa.agqvqlaspGapgsv 219 + + + ++sp r+ d +++ r++sl+++s + f + G+g+ l + v ++++G gs+ FUN_000274-T1 106 EGYYVYIETSSPRRLGDKAIISRRVSLTGKSCLSFFYHMRGSGMGTLRVKlCDAVIFEKSGNQGSI 171 4555678899***********************************998887888999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 518 (0.0202779); expected 510.9 (0.02) Passed bias filter: 474 (0.0185555); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2145.88 // Query: FUN_000274-T2 [L=402] Description: FUN_000274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-59 200.1 0.0 4.8e-59 199.6 0.0 1.2 1 Astacin Astacin (Peptidase family M12A) 4.9e-31 108.2 0.0 8.1e-31 107.5 0.0 1.4 1 MAM MAM domain, meprin/A5/mu 0.0012 19.0 0.1 0.0019 18.3 0.1 1.4 1 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like 0.0029 18.0 4.1 0.094 13.1 1.4 2.6 3 Peptidase_M10 Matrixin ------ inclusion threshold ------ 0.082 12.2 0.0 0.099 11.9 0.0 1.1 1 EP400_N E1A-binding protein p400, N-terminal 0.082 13.6 0.0 0.13 12.9 0.0 1.3 1 Reprolysin_5 Metallo-peptidase family M12 0.11 13.5 0.0 0.2 12.7 0.0 1.5 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like 0.25 11.7 0.4 0.46 10.8 0.1 1.5 2 Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like 0.38 10.4 0.7 0.62 9.7 0.7 1.3 1 DUF4953 Met-zincin Domain annotation for each model (and alignments): >> Astacin Astacin (Peptidase family M12A) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 199.6 0.0 1.7e-62 4.8e-59 2 186 .] 53 234 .. 52 234 .. 0.96 Alignments for each domain: == domain 1 score: 199.6 bits; conditional E-value: 1.7e-62 Astacin 2 wpeakipYeleeslee.keraaiakaleeyekkt..CikfkereaseenylkvtkgegClSevGraggkqevslgkgCeklgiivHElgHalGffH 94 w++a+ Y +e+sl++ +++++ia+a++ +++kt Cikf +r+ ++ y ++++g+gC+S+vGr+g kq++sl +gC gi++HE+gHalGf H FUN_000274-T2 53 WEKAEFVYDIESSLDDpRAKRVIASAMAAWNSKTngCIKFIKRT-NQAAYASFFRGSGCWSYVGRTGRKQQISLARGCWYHGIVAHEIGHALGFLH 147 999**********97537899*********998878********.999************************************************ PP Astacin 95 eqsRtdrdeyvsinkeniekgqeenfekvdskevdslgvpYdygSimhYakkafskngaleTivpkkeelqktiGqreklsevDikkinklY 186 eqsR+drd yv+i+ eni++g+e+nf+k + +++s g+pYdygSimhY+++afskng ++Ti+pk+ tiG+r+ ls +D++++ lY FUN_000274-T2 148 EQSRPDRDAYVEIKFENIQSGKENNFRKSN--SINSFGTPYDYGSIMHYRANAFSKNG-QPTIIPKRA--GVTIGNRRALSPIDVQQMMLLY 234 **************************9987..9***********************99.8******99..78****************9888 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.5 0.0 2.8e-34 8.1e-31 1 157 [. 257 402 .] 257 402 .] 0.94 Alignments for each domain: == domain 1 score: 107.5 bits; conditional E-value: 2.8e-34 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvll 93 C+F++g +Cg++qd++d++dW+r++++ s++tgp dh+ g+G+y+++etss + g+ ++s+ ++ + k +Cl+F+yhm+gs+ gtlrv l FUN_000274-T2 257 CNFNNG-MCGFIQDQDDQFDWTRKKGQtqSSNTGPLGDHN--GEGYYVYIETSSPrRLGD-KAIISRRVSLTGK-SCLSFFYHMRGSGMGTLRVKL 347 ******.******************99999**********..************955555.6688999999999.9******************99 PP MAM 94 reegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 + ++++ sg+qg+ W ++e+ l+ + +++fe++rg++ +gd a+Dd+ + ++C FUN_000274-T2 348 CD------AVIFEKSGNQGSIWLKQELRLQG-SGTKKLIFEGIRGRNFRGDAAIDDVMI--YDC 402 64......5899*******************.*************************98..555 PP >> Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 6.7e-07 0.0019 102 161 .. 96 166 .. 64 216 .. 0.61 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 6.7e-07 Reprolysin_4 102 drasqqevgvawv.gavcls..arqvnkkgsgfaassderdey.ditfAHEiGHqfGaaHdke...............s 161 + +q++ +++ g +c s r k+ a++ y i +AHEiGH +G H+ + + FUN_000274-T2 96 T---NQAAYASFFrGSGCWSyvGRTGRKQQISLARG----CWYhGI-VAHEIGHALGFLHEQSrpdrdayveikfeniQ 166 2...34444444415555554444444455555555....334366.*************9985555555444444441 PP >> Peptidase_M10 Matrixin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.1 0.012 34 2 49 .. 53 99 .. 52 108 .. 0.78 2 ! 13.1 1.4 3.3e-05 0.094 107 128 .. 130 151 .. 111 175 .. 0.84 3 ? -1.9 0.0 1.3 3.8e+03 49 71 .. 155 177 .. 149 196 .. 0.77 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.012 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF Peptidase_M10 2 wekkeltyrilnetpdlseeevrkairkAfkvwsevtp..lkFtevkege 49 wek e y i ++ l++ + +++i++A+++w+++t+ +kF + ++++ FUN_000274-T2 53 WEKAEFVYDIESS---LDDPRAKRVIASAMAAWNSKTNgcIKFIKRTNQA 99 6677777777654...5668999**************8789998876554 PP == domain 2 score: 13.1 bits; conditional E-value: 3.3e-05 xxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 107 dlflvavHeiGHaLGLeHssde 128 + +++HeiGHaLG H +++ FUN_000274-T2 130 WYHGIVAHEIGHALGFLHEQSR 151 566799************8764 PP == domain 3 score: -1.9 bits; conditional E-value: 1.3 xxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 49 eadikikFargehgdgepfDgkg 71 +a ++ikF++ + g++++f ++ FUN_000274-T2 155 DAYVEIKFENIQSGKENNFRKSN 177 67789999999999988886555 PP >> EP400_N E1A-binding protein p400, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 3.5e-05 0.099 157 219 .. 299 362 .. 202 377 .. 0.77 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.5e-05 EP400_N 157 talGlcgqsptrfvdasllvrqislgsssggghfvyqdGtglaqlasa.agqvqlaspGapgsv 219 + + ++sp r+ d +++ r++sl+++s + f + G+g+ l + v ++++G gs+ FUN_000274-T2 299 YYVYIETSSPRRLGDKAIISRRVSLTGKSCLSFFYHMRGSGMGTLRVKlCDAVIFEKSGNQGSI 362 45667899**********************************9998887888999999999887 PP >> Reprolysin_5 Metallo-peptidase family M12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 4.5e-05 0.13 82 158 .. 79 149 .. 55 201 .. 0.66 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 4.5e-05 Reprolysin_5 82 ssawrgtqsddlavltlmtncstgvglAwl..gqlcnsgsagsvsesveksnsvvvstatewqvfaHEiGHnfGavHDc 158 aw+++ + ++ ++ + ++ +A+ g+ c+s +++ ++ + + + + ++aHEiGH +G H FUN_000274-T2 79 MAAWNSKTNGCIKFIKRT---NQA-AYASFfrGSGCWSYVGRTGRKQ----QISLARGCWYHGIVAHEIGHALGFLHEQ 149 566666666655554443...222.2222235777777776666666....3445556677789**********99943 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 7e-05 0.2 96 122 .. 126 147 .. 57 148 .. 0.67 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 7e-05 Reprolysin_3 96 nsgssplgdtga.....dtfaHEiGHnfGanH 122 +aHEiGH +G H FUN_000274-T2 126 A----------RgcwyhGIVAHEIGHALGFLH 147 2..........02233489**********888 PP >> Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 4.5 1.3e+04 38 53 .. 74 89 .. 60 102 .. 0.58 2 ? 10.8 0.1 0.00016 0.46 128 146 .. 134 152 .. 126 199 .. 0.81 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 4.5 Reprolysin_2 38 attsasdsgnnrcnss 53 +++sa +++n ++n FUN_000274-T2 74 VIASAMAAWNSKTNGC 89 4555556665544433 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00016 Reprolysin_2 128 vvaHEvGHnFGatHdndgs 146 +vaHE+GH+ G H++ FUN_000274-T2 134 IVAHEIGHALGFLHEQSRP 152 89************98755 PP >> DUF4953 Met-zincin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.7 0.00022 0.62 16 30 .. 134 148 .. 130 150 .. 0.90 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00022 DUF4953 16 vsaHEVGHtLGLrhN 30 ++aHE+GH+LG+ h FUN_000274-T2 134 IVAHEIGHALGFLHE 148 89**********995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 607 (0.023762); expected 510.9 (0.02) Passed bias filter: 574 (0.0224702); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.33u 0.34s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 4051.40 // Query: FUN_000274-T3 [L=173] Description: FUN_000274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-32 111.1 0.0 8e-32 110.8 0.0 1.1 1 MAM MAM domain, meprin/A5/mu ------ inclusion threshold ------ 0.02 14.2 0.0 0.021 14.2 0.0 1.1 1 EP400_N E1A-binding protein p400, N-terminal Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.8 0.0 6.2e-36 8e-32 1 157 [. 28 173 .] 28 173 .] 0.94 Alignments for each domain: == domain 1 score: 110.8 bits; conditional E-value: 6.2e-36 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvll 93 C+F++g +Cg++qd++d++dW+r++++ s++tgp dh+ g+G+y+++etss + g+ ++s+ ++ + k +Cl+F+yhm+gs+ gtlrv l FUN_000274-T3 28 CNFNNG-MCGFIQDQDDQFDWTRKKGQtqSSNTGPLGDHN--GEGYYVYIETSSPrRLGD-KAIISRRVSLTGK-SCLSFFYHMRGSGMGTLRVKL 118 ******.******************99999**********..************955555.6688999999999.9******************99 PP MAM 94 reegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 + ++++ sg+qg+ W ++e+ l+ + +++fe++rg++ +gd a+Dd+ + ++C FUN_000274-T3 119 CD------AVIFEKSGNQGSIWLKQELRLQG-SGTKKLIFEGIRGRNFRGDAAIDDVMI--YDC 173 64......5899*******************.*************************98..555 PP >> EP400_N E1A-binding protein p400, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 1.7e-06 0.021 158 219 .. 71 133 .. 10 148 .. 0.77 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.7e-06 EP400_N 158 alGlcgqsptrfvdasllvrqislgsssggghfvyqdGtglaqlasa.agqvqlaspGapgsv 219 + + ++sp r+ d +++ r++sl+++s + f + G+g+ l + v ++++G gs+ FUN_000274-T3 71 YVYIETSSPRRLGDKAIISRRVSLTGKSCLSFFYHMRGSGMGTLRVKlCDAVIFEKSGNQGSI 133 5667899***********************************998887888999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (173 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 346 (0.0135447); expected 510.9 (0.02) Passed bias filter: 299 (0.0117048); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1728.32 // Query: FUN_000274-T4 [L=391] Description: FUN_000274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-59 200.2 0.0 4.5e-59 199.7 0.0 1.2 1 Astacin Astacin (Peptidase family M12A) 4.6e-31 108.3 0.0 7.6e-31 107.6 0.0 1.4 1 MAM MAM domain, meprin/A5/mu 0.0011 19.1 0.1 0.0018 18.4 0.1 1.4 1 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like 0.0022 18.4 3.8 0.099 13.0 1.3 2.6 3 Peptidase_M10 Matrixin ------ inclusion threshold ------ 0.078 12.3 0.0 0.094 12.0 0.0 1.1 1 EP400_N E1A-binding protein p400, N-terminal 0.079 13.6 0.0 0.12 13.0 0.0 1.3 1 Reprolysin_5 Metallo-peptidase family M12 0.11 13.5 0.0 0.19 12.7 0.0 1.5 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like 0.24 11.7 0.4 0.44 10.9 0.1 1.6 2 Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like 0.36 10.5 0.7 0.6 9.8 0.7 1.3 1 DUF4953 Met-zincin Domain annotation for each model (and alignments): >> Astacin Astacin (Peptidase family M12A) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 199.7 0.0 1.6e-62 4.5e-59 2 186 .] 42 223 .. 41 223 .. 0.96 Alignments for each domain: == domain 1 score: 199.7 bits; conditional E-value: 1.6e-62 Astacin 2 wpeakipYeleeslee.keraaiakaleeyekkt..CikfkereaseenylkvtkgegClSevGraggkqevslgkgCeklgiivHElgHalGffH 94 w++a+ Y +e+sl++ +++++ia+a++ +++kt Cikf +r+ ++ y ++++g+gC+S+vGr+g kq++sl +gC gi++HE+gHalGf H FUN_000274-T4 42 WEKAEFVYDIESSLDDpRAKRVIASAMAAWNSKTngCIKFIKRT-NQAAYASFFRGSGCWSYVGRTGRKQQISLARGCWYHGIVAHEIGHALGFLH 136 999**********97537899*********998878********.999************************************************ PP Astacin 95 eqsRtdrdeyvsinkeniekgqeenfekvdskevdslgvpYdygSimhYakkafskngaleTivpkkeelqktiGqreklsevDikkinklY 186 eqsR+drd yv+i+ eni++g+e+nf+k + +++s g+pYdygSimhY+++afskng ++Ti+pk+ tiG+r+ ls +D++++ lY FUN_000274-T4 137 EQSRPDRDAYVEIKFENIQSGKENNFRKSN--SINSFGTPYDYGSIMHYRANAFSKNG-QPTIIPKRA--GVTIGNRRALSPIDVQQMMLLY 223 **************************9987..9***********************99.8******99..78****************9888 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.6 0.0 2.7e-34 7.6e-31 1 157 [. 246 391 .] 246 391 .] 0.94 Alignments for each domain: == domain 1 score: 107.6 bits; conditional E-value: 2.7e-34 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvll 93 C+F++g +Cg++qd++d++dW+r++++ s++tgp dh+ g+G+y+++etss + g+ ++s+ ++ + k +Cl+F+yhm+gs+ gtlrv l FUN_000274-T4 246 CNFNNG-MCGFIQDQDDQFDWTRKKGQtqSSNTGPLGDHN--GEGYYVYIETSSPrRLGD-KAIISRRVSLTGK-SCLSFFYHMRGSGMGTLRVKL 336 ******.******************99999**********..************955555.6688999999999.9******************99 PP MAM 94 reegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 + ++++ sg+qg+ W ++e+ l+ + +++fe++rg++ +gd a+Dd+ + ++C FUN_000274-T4 337 CD------AVIFEKSGNQGSIWLKQELRLQG-SGTKKLIFEGIRGRNFRGDAAIDDVMI--YDC 391 64......5899*******************.*************************98..555 PP >> Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 6.4e-07 0.0018 102 161 .. 85 155 .. 53 205 .. 0.61 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 6.4e-07 Reprolysin_4 102 drasqqevgvawv.gavcls..arqvnkkgsgfaassderdey.ditfAHEiGHqfGaaHdke...............s 161 + +q++ +++ g +c s r k+ a++ y i +AHEiGH +G H+ + + FUN_000274-T4 85 T---NQAAYASFFrGSGCWSyvGRTGRKQQISLARG----CWYhGI-VAHEIGHALGFLHEQSrpdrdayveikfeniQ 155 2...34444444415556554444444455555555....334366.*************9985555555444444441 PP >> Peptidase_M10 Matrixin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.011 32 2 49 .. 42 88 .. 41 98 .. 0.78 2 ! 13.0 1.3 3.5e-05 0.099 108 128 .. 120 140 .. 108 164 .. 0.84 3 ? -2.1 0.0 1.5 4.3e+03 49 71 .. 144 166 .. 140 185 .. 0.77 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.011 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF Peptidase_M10 2 wekkeltyrilnetpdlseeevrkairkAfkvwsevtp..lkFtevkege 49 wek e y i ++ l++ + +++i++A+++w+++t+ +kF + ++++ FUN_000274-T4 42 WEKAEFVYDIESS---LDDPRAKRVIASAMAAWNSKTNgcIKFIKRTNQA 88 6677777777654...5668999**************8789998876554 PP == domain 2 score: 13.0 bits; conditional E-value: 3.5e-05 xxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 108 lflvavHeiGHaLGLeHssde 128 + +++HeiGHaLG H +++ FUN_000274-T4 120 YHGIVAHEIGHALGFLHEQSR 140 66799************8764 PP == domain 3 score: -2.1 bits; conditional E-value: 1.5 xxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 49 eadikikFargehgdgepfDgkg 71 +a ++ikF++ + g++++f ++ FUN_000274-T4 144 DAYVEIKFENIQSGKENNFRKSN 166 57789999999999888886554 PP >> EP400_N E1A-binding protein p400, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 3.3e-05 0.094 157 219 .. 288 351 .. 191 366 .. 0.77 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 3.3e-05 EP400_N 157 talGlcgqsptrfvdasllvrqislgsssggghfvyqdGtglaqlasa.agqvqlaspGapgsv 219 + + ++sp r+ d +++ r++sl+++s + f + G+g+ l + v ++++G gs+ FUN_000274-T4 288 YYVYIETSSPRRLGDKAIISRRVSLTGKSCLSFFYHMRGSGMGTLRVKlCDAVIFEKSGNQGSI 351 45667899**********************************9998887888999999999887 PP >> Reprolysin_5 Metallo-peptidase family M12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 4.3e-05 0.12 82 158 .. 68 138 .. 44 190 .. 0.66 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.3e-05 Reprolysin_5 82 ssawrgtqsddlavltlmtncstgvglAwl..gqlcnsgsagsvsesveksnsvvvstatewqvfaHEiGHnfGavHDc 158 aw+++ + ++ ++ + ++ +A+ g+ c+s +++ ++ + + + + ++aHEiGH +G H FUN_000274-T4 68 MAAWNSKTNGCIKFIKRT---NQA-AYASFfrGSGCWSYVGRTGRKQ----QISLARGCWYHGIVAHEIGHALGFLHEQ 138 566666666655554443...222.2222235777777776666666....3445556677789**********99943 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 6.7e-05 0.19 96 122 .. 115 136 .. 46 137 .. 0.67 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 6.7e-05 Reprolysin_3 96 nsgssplgdtga.....dtfaHEiGHnfGanH 122 +aHEiGH +G H FUN_000274-T4 115 A----------RgcwyhGIVAHEIGHALGFLH 136 2..........02233489**********888 PP >> Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 4 1.1e+04 38 53 .. 63 78 .. 48 92 .. 0.58 2 ? 10.9 0.1 0.00016 0.44 128 146 .. 123 141 .. 115 188 .. 0.81 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 4 Reprolysin_2 38 attsasdsgnnrcnss 53 +++sa +++n ++n FUN_000274-T4 63 VIASAMAAWNSKTNGC 78 5555666666544433 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00016 Reprolysin_2 128 vvaHEvGHnFGatHdndgs 146 +vaHE+GH+ G H++ FUN_000274-T4 123 IVAHEIGHALGFLHEQSRP 141 8*************98755 PP >> DUF4953 Met-zincin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.7 0.00021 0.6 16 30 .. 123 137 .. 119 139 .. 0.90 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00021 DUF4953 16 vsaHEVGHtLGLrhN 30 ++aHE+GH+LG+ h FUN_000274-T4 123 IVAHEIGHALGFLHE 137 89**********995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (391 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 565 (0.0221178); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3913.25 // Query: FUN_000275-T1 [L=100] Description: FUN_000275 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 435 (0.0170288); expected 510.9 (0.02) Passed bias filter: 410 (0.0160501); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1013.81 // Query: FUN_000276-T1 [L=231] Description: FUN_000276 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-06 28.3 0.0 2.9e-06 27.7 0.0 1.4 1 Thioredoxin Thioredoxin 0.00027 20.9 0.1 0.00049 20.1 0.1 1.4 1 OST3_OST6 OST3 / OST6 family, transporter family 0.0026 18.0 0.1 0.0047 17.2 0.1 1.4 1 FAM176 FAM176 family ------ inclusion threshold ------ 0.042 14.2 0.1 0.058 13.7 0.1 1.2 1 Thioredoxin_6 Thioredoxin-like domain 0.23 12.5 0.2 0.23 12.5 0.2 1.6 2 Got1 Got1/Sft2-like family Domain annotation for each model (and alignments): >> Thioredoxin Thioredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 5.7e-10 2.9e-06 28 103 .] 56 131 .. 21 131 .. 0.85 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 5.7e-10 Thioredoxin 28 pwCGpCkalaPeleelaeelkdkvklakvdvdenkelakkyevegiPtlklfkngkevekyegarekeelaafikk 103 p C+ Ck+ ++++ e+l++k+++a v ++k + k+++v P ++l+k+gk+ eg+ ++e++++fi+k FUN_000276-T1 56 PECTECKKADEAIAKAQEKLSHKLNFALVLPPKSKLTLKRFDVARWPHVILLKQGKQYTYSEGKMDEESFIRFIEK 131 67*********************************************************************99975 PP >> OST3_OST6 OST3 / OST6 family, transporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.1 9.7e-08 0.00049 15 139 .. 24 134 .. 18 185 .. 0.80 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 9.7e-08 OST3_OST6 15 klndsnykell...kgprdysvvvllTatdpqrkCelCrefepefelvakswqkdekkeskklfFakldfdegkevfqklglqtvPhlllfpptkg 107 lnd+++++l+ +g + +++++ td+ +C+ C+++++ + ak+ k s+kl Fa + ++k + +++ + Ph++l + FUN_000276-T1 24 ILNDESFEHLTqasTGATTGDWFIVFSFTDKDPECTECKKADEAI---AKAQE----KLSHKLNFALVLPPKSKLTLKRFDVARWPHVILLKQ--- 109 59*********66435556666777777777889******99765...44443....44789*****************************98... PP OST3_OST6 108 pkksskepdeydfseggfsaeqlaeflsertg 139 ++y seg+++ e++++f+++ + FUN_000276-T1 110 -------GKQYTYSEGKMDEESFIRFIEKGYE 134 .......34788889999********998776 PP >> FAM176 FAM176 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.1 9.2e-07 0.0047 19 83 .. 167 229 .. 161 231 .] 0.53 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 9.2e-07 FAM176 19 pEraaLyFvlgvcvGLvltLcllViriscrkdlkklakkkkelkeeseedeedseeeeeeeeeds 83 aa++F gv +GL+lt +l + c + +++++++ l+e +de d++e+++eeee++ FUN_000276-T1 167 KNAAAVIFFAGVLFGLMLTPVLKLL-AECLINSFTQEPDQD-LDEGLGQDEVDEDEDQNEEEEKK 229 56799**************765433.334433333333322.22233334444444444444433 PP >> Thioredoxin_6 Thioredoxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 1.1e-05 0.058 98 184 .] 47 131 .. 23 131 .. 0.84 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.1e-05 Thioredoxin_6 98 llllflkkddeet..ekfkkalekvakkfkgkinfalvdaksfkrlleylglsesdlPviaiidsfshkykffp.edeispeslkeFind 184 ++ f++kd e t +k+ +a+ k+ +k++ k+nfalv + k l+++++ P +++++ + +++ + e+++++es+ Fi++ FUN_000276-T1 47 IVFSFTDKDPECTecKKADEAIAKAQEKLSHKLNFALVLPPKSKLTLKRFDVA--RWPHVILLK---QGKQYTYsEGKMDEESFIRFIEK 131 57889999988874459999*******************999999*****555..******888...44445454************986 PP >> Got1 Got1/Sft2-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.3 2 1e+04 69 78 .. 4 13 .. 1 25 [. 0.50 2 ? 12.5 0.2 4.5e-05 0.23 47 94 .. 151 198 .. 149 201 .. 0.88 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2 Got1 69 vylvsllltL 78 +y++ ++l + FUN_000276-T1 4 CYICAFILLF 13 3333333322 PP == domain 2 score: 12.5 bits; conditional E-value: 4.5e-05 Got1 47 fLiGpkkqlkhlfskerliativylvsllltLyfalvlksylltllfa 94 f+ G++ +kh+++ + a++++++++l L+++ vlk +l+ + FUN_000276-T1 151 FIEGLMDDIKHMIQLRKNAAAVIFFAGVLFGLMLTPVLKLLAECLINS 198 899******************************999998877777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (231 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1177 (0.0460756); expected 510.9 (0.02) Passed bias filter: 821 (0.0321394); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.24u 0.43s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 2374.49 // Query: FUN_000277-T1 [L=202] Description: FUN_000277 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-23 83.3 4.6 2.7e-23 82.6 4.6 1.3 1 SUEL_Lectin D-galactoside/L-rhamnose binding SUEL lectin dom ------ inclusion threshold ------ 0.036 14.2 0.1 0.12 12.5 0.2 1.8 2 GIT_CC GIT coiled-coil Rho guanine nucleotide exchange 0.042 14.7 0.0 0.071 14.0 0.0 1.4 1 BLOC1_2 Biogenesis of lysosome-related organelles comple 0.11 13.4 0.1 0.18 12.7 0.1 1.4 1 DNA_PPF DNA polymerase processivity factor 0.35 11.8 1.9 0.66 10.9 1.9 1.4 1 FlaC_arch Flagella accessory protein C (FlaC) Domain annotation for each model (and alignments): >> SUEL_Lectin D-galactoside/L-rhamnose binding SUEL lectin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.6 4.6 5.2e-27 2.7e-23 1 80 [] 122 200 .. 122 200 .. 0.98 Alignments for each domain: == domain 1 score: 82.6 bits; conditional E-value: 5.2e-27 SUEL_Lectin 1 lsCpegkvisvksAsyGrtegetCpgsaaegtnCeaseslakvkkaCqgkesCsvevsnevfggdpCpgvykyLeveykC 80 l C+ g+++++ +A yGr++++tC+g ++t+C+a++sla+v+k C+gk sC ++++n+vf gdpC g+ kyL+v+y+C FUN_000277-T1 122 LACKAGQKMKIVQARYGRSNKRTCKGGPIRTTKCKATKSLAIVRKYCHGKASCVLRANNSVF-GDPCAGTLKYLNVRYRC 200 78***********************99999999*****************************.***************** PP >> GIT_CC GIT coiled-coil Rho guanine nucleotide exchange factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.2 2.4e-05 0.12 29 55 .. 62 88 .. 58 92 .. 0.92 2 ? -2.8 0.0 1.5 7.7e+03 12 24 .. 111 123 .. 109 128 .. 0.80 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2.4e-05 GIT_CC 29 eakiqqLlkvNtnlseeLreLQkkvqt 55 e+ +++L +vN n+ + L+++ kkv++ FUN_000277-T1 62 ESSVKHLKRVNKNMMNRLKKMDKKVDN 88 8899********************986 PP == domain 2 score: -2.8 bits; conditional E-value: 1.5 GIT_CC 12 pvtvqeYlevKea 24 +t+ eY e K a FUN_000277-T1 111 SITICEYREAKLA 123 6999999998865 PP >> BLOC1_2 Biogenesis of lysosome-related organelles complex-1 subunit 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 1.4e-05 0.071 16 55 .. 59 98 .. 45 111 .. 0.85 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.4e-05 BLOC1_2 16 eataedlklLeklNeatsekykklkdvasslekeleelke 55 ++++ +k L+++N++++ + kk++++++++ + + ++ + FUN_000277-T1 59 GVIESSVKHLKRVNKNMMNRLKKMDKKVDNIMRIMRKVMK 98 5677899************************998887765 PP >> DNA_PPF DNA polymerase processivity factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 3.6e-05 0.18 60 114 .. 74 132 .. 20 133 .. 0.72 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 3.6e-05 DNA_PPF 60 nqltsvvapvkndedniekLlaeikssedgnvkiadlsS.....yqeaykslvsgenkai 114 n ++ + k++ dni ++ ++ + + ++k+ +lsS y ea ++g+ i FUN_000277-T1 74 NMMNRLKKMDKKV-DNIMRIMRKVMKGDKPSIKPRNLSSiticeYREAKLACKAGQKMKI 132 3333344444555.79********************************999999987666 PP >> FlaC_arch Flagella accessory protein C (FlaC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 1.9 0.00013 0.66 8 43 .. 57 92 .. 55 98 .. 0.92 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00013 FlaC_arch 8 klekleseletlrkeneeisksveeieenvkkllsl 43 +++ +es+++ l++ n++ +++++++++v++++ + FUN_000277-T1 57 RIGVIESSVKHLKRVNKNMMNRLKKMDKKVDNIMRI 92 57789*************************999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (202 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1966 (0.0769622); expected 510.9 (0.02) Passed bias filter: 1186 (0.0464279); expected 510.9 (0.02) Passed Vit filter: 119 (0.00465845); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.26u 0.44s 00:00:00.70 Elapsed: 00:00:00.47 # Mc/sec: 1739.99 // Query: FUN_000278-T1 [L=111] Description: FUN_000278 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (111 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 669 (0.0261891); expected 510.9 (0.02) Passed bias filter: 440 (0.0172245); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.33s 00:00:00.61 Elapsed: 00:00:00.45 # Mc/sec: 986.92 // Query: FUN_000279-T1 [L=211] Description: FUN_000279 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 661 (0.0258759); expected 510.9 (0.02) Passed bias filter: 544 (0.0212958); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2131.61 // Query: FUN_000280-T1 [L=296] Description: FUN_000280 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 15.7 0.2 0.021 15.0 0.2 1.3 1 DUF6768 Family of unknown function (DUF6768) Domain annotation for each model (and alignments): >> DUF6768 Family of unknown function (DUF6768) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.2 8.3e-07 0.021 49 96 .. 25 72 .. 3 82 .. 0.87 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 8.3e-07 DUF6768 49 ivqivffvlfvycavqffqaeevnelikWgvgalvlllvvamlKlflw 96 ++ ++f++++y+++ +f + ++ + ++W + ++v++++ +++ ++l FUN_000280-T1 25 VACSLAFCITIYIFYPVFYEGDATKGLRWFISCIVVFVLLSVVSISLK 72 566789*******************************99998877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (296 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 674 (0.0263848); expected 510.9 (0.02) Passed bias filter: 504 (0.0197299); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.51 # Mc/sec: 2333.28 // Query: FUN_000281-T1 [L=208] Description: FUN_000281 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-07 30.8 2.0 3.4e-07 30.4 2.0 1.1 1 YdjM YdjM inner membrane protein Domain annotation for each model (and alignments): >> YdjM YdjM inner membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 2.0 1.3e-11 3.4e-07 2 130 .. 48 173 .. 47 196 .. 0.81 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 1.3e-11 YdjM 2 dtltHallGaalglaaakrlksakeaalllagllgallPDiDhpksklgrrlpylsnvgHRgftHSllfllllalllalllalfars.lslgllll 96 d++tH +++ + + ++++ +++++ + ++ g+++ + D+Dh+ + +l+ + +++ R f HS ++++++ +l ++la++ ++ +sl +l++ FUN_000281-T1 48 DNFTHGIISCISWCIVSEIRTPRDVIDAISSGIIA-CSLDVDHFVAAKSLNLQDVLHLQNRPFLHSTTVVFIVVPMLEVFLAQNIPYlQSLPYLFA 142 789*****************999887788888876.888***999888888888888899*********9999888888888888775778888** PP YdjM 97 lgylsHlllDlltsyGvqllwPfskkrirlgllf 130 ++++sH l D ++G ++wP+ + + +++ ++ FUN_000281-T1 143 VAIISHHLRDGH-RRG-LWFWPIGS-TPAIPYWL 173 **********65.455.58***965.44444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 638 (0.0249755); expected 510.9 (0.02) Passed bias filter: 464 (0.018164); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.49 # Mc/sec: 1726.70 // Query: FUN_000282-T1 [L=995] Description: FUN_000282 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 5.1 7.2 5.7 23 5.1 5.7 2.3 1 Arm-DNA-bind_4 Arm DNA-binding domain Domain annotation for each model (and alignments): >> Arm-DNA-bind_4 Arm DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 5.7 0.0009 23 1 29 [. 277 301 .. 277 302 .. 0.93 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0009 Arm-DNA-bind_4 1 kWyfqvyvgydditGkrKqktkrGFkTkk 29 kW++ + g + +G+r++k kr k+kk FUN_000282-T1 277 KWHVAH--GQTKRDGNRRYKVKR--KKKK 301 8*****..99999**********..8887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (995 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1386 (0.0542572); expected 510.9 (0.02) Passed bias filter: 564 (0.0220787); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.41u 0.45s 00:00:00.86 Elapsed: 00:00:00.55 # Mc/sec: 7301.87 // Query: FUN_000283-T1 [L=504] Description: FUN_000283 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-63 215.1 0.4 1.4e-63 214.7 0.4 1.1 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 3.1e-53 181.9 0.1 3.9e-53 181.6 0.1 1.1 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.11 13.3 1.8 0.27 12.1 1.8 1.6 1 DUF7536 Family of unknown function (DUF7536) Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 214.7 0.4 1.6e-67 1.4e-63 3 216 .] 44 251 .. 42 251 .. 0.97 Alignments for each domain: == domain 1 score: 214.7 bits; conditional E-value: 1.6e-67 Neur_chan_LBD 3 rlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlynkadgehe 98 rll+dl+++Ydk+vrPv n+s++v+V+++lsl qiisv++k+q lt+nvw++q+W+ + L+wn++dyggies++l+ +k+W+Pd++lyn+ad+++ FUN_000283-T1 44 RLLRDLFKDYDKEVRPVYNTSEAVNVEFSLSLIQIISVNSKSQLLTLNVWIRQRWKNPILAWNTSDYGGIESVNLDPSKVWIPDVILYNNADDSYG 139 89*****************************************************************************************99996 PP Neur_chan_LBD 99 ..vtekntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakree 192 ++++t v+++ dG w+ p +++s+C+i+v +FPfD+qnCslkf+Swt++++ +++ ++ +++dl+ f++ngew+l ++ak + FUN_000283-T1 140 ggLEKYKTSVILKADGYNEWNAPCSFTSTCKIQVANFPFDKQNCSLKFGSWTFQGDRLTMASTD-------SSADLELFMQNGEWNLLAMPAKLNV 228 3367789999****************************************************99.......799********************** PP Neur_chan_LBD 193 kktgsyselsysdvtftltlrRkp 216 + +++ + y+dvt++l+++Rkp FUN_000283-T1 229 VRYPCCKYP-YHDVTLNLIIKRKP 251 ****99998.8***********97 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 181.6 0.1 4.6e-57 3.9e-53 1 233 [] 258 497 .. 258 497 .. 0.91 Alignments for each domain: == domain 1 score: 181.6 bits; conditional E-value: 4.6e-57 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 li+Pc li+ L+ + F+Lp+++ gekv LgItvlL++Tvflll++e+lP+tS vpl+g+Y++ +m ++ +slv t +Vln++hrspst +m++w FUN_000283-T1 258 LILPCALISTLTLILFFLPPES-GEKVGLGITVLLAMTVFLLLVAETLPATSDDVPLLGQYFIATMFVTAMSLVSTCTVLNFFHRSPSTSPMPRW 351 69********************.************************************************************************ PP Neur_chan_memb 96 vrklfleklprlllmkrpkeeeeeea..........ssagssskaeelilkksrselkaekqsersglerettestessegkelkqseelspele 180 vr + l + ++ ++k ++e+e ++a + +g ++e+++ + s k+ + ++ +++++++t+s+ s ++ +l ++ ++ FUN_000283-T1 352 VRVIILGYMAKVFCFKIEREDEIKMApknkrkriefDLNGDIPLEDEIYMSLPVSPRKFRDDMSLVSQSGRSTPSKRSVRSMSLV--GGQNSFAD 444 ****************998888877776766666666666666999999999999999999999999999999988886555553..45555568 PP Neur_chan_memb 181 kaveevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 + +e +n +a+ +r ++++e+ +e+w ++a v+Dr+++++f+++++l t++if FUN_000283-T1 445 RLLEDINTLAEDVRARQEDERQREEWRMAALVLDRMFFWLFLFLTLLSTFLIF 497 99999*********************************************998 PP >> DUF7536 Family of unknown function (DUF7536) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 1.8 3.1e-05 0.27 22 79 .. 282 335 .. 278 340 .. 0.85 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.1e-05 DUF7536 22 aigvavgvalavlvYavrvlellgpvagtreypvlGpegwflvLafvLavatallvta 79 ++g+ + v+la++v+++ v e l + + ++p+lG+ +f++ fv a+++ + t+ FUN_000283-T1 282 KVGLGITVLLAMTVFLLLVAETLPATSD--DVPLLGQ--YFIATMFVTAMSLVSTCTV 335 7999***************998866555..59***98..9*******99998776664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (504 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1041 (0.0407516); expected 510.9 (0.02) Passed bias filter: 706 (0.0276375); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.61s 00:00:00.98 Elapsed: 00:00:00.54 # Mc/sec: 3803.13 // Query: FUN_000284-T1 [L=304] Description: FUN_000284 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (304 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 451 (0.0176551); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 3129.40 // Query: FUN_000285-T1 [L=461] Description: FUN_000285 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-36 125.4 1.4 2e-33 116.4 0.2 2.6 3 RabGAP-TBC Rab-GTPase-TBC domain 5.1e-09 36.6 0.6 5.1e-09 36.6 0.6 1.6 2 RabGap-TBC_2 RabGAP TBC domain ------ inclusion threshold ------ 0.12 12.4 0.0 0.24 11.3 0.0 1.5 1 Zwint ZW10 interactor Domain annotation for each model (and alignments): >> RabGAP-TBC Rab-GTPase-TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.00054 4.6 2 59 .. 81 141 .. 80 159 .. 0.68 2 ! 116.4 0.2 2.3e-37 2e-33 42 193 .. 200 348 .. 186 357 .. 0.88 3 ? -3.1 0.0 0.82 7e+03 201 216 .] 393 408 .. 388 408 .. 0.82 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.00054 RabGAP-TBC 2 elRgkvWklllgaek...evkklkkeekkqeksskeeselekkeeseeeeqIekDvprtfp 59 ++R++vW++l g + +++ + +++e++ + ++ k+ ++++ +e Dvp ++p FUN_000285-T1 81 RIRKDVWSFLFGLFPfssTRREREALGAENEARYQALKMRWKELVQTYQPPVESDVPESIP 141 79***********99995444444444444455555555555555666999*****99999 PP == domain 2 score: 116.4 bits; conditional E-value: 2.3e-37 RabGAP-TBC 42 eeseeeeqIekDvprtfphs..fsfkngegqesLrriLkaysiynpdvgYcqGmnfivapllllyldeeeaFwcfvsLlekyklrdlytsdfpglk 135 + +++++ I+kDvprt +++ f k +++ Lr iL +ys y+pdvgY+qGmn+i++ +l++ +e+ea+wcfv+ + + rd+ ++ + FUN_000285-T1 200 KLHSSIRVIDKDVPRTDRSQvfFAGKGNQNLLVLRDILITYSAYHPDVGYVQGMNDILSRFLIVLGSETEAYWCFVNYM-ETVKRDFLDDG---ML 291 56677999**********66677778889999******************************9999*************.56667777776...56 PP RabGAP-TBC 136 kalkvfeellkkklpklykhlkelgidlelfalkWfltlflrefplslvlriwDvlll 193 +++++ llk+ +++ly+h++++g+ lf+++W+ f refp+ +l +++ ++ FUN_000285-T1 292 HKVEQVSVLLKRLDEHLYNHFQSQGMGDILFVHRWLVLSFKREFPYGDALTMFE-IIS 348 667899***********************************************9.443 PP == domain 3 score: -3.1 bits; conditional E-value: 0.82 RabGAP-TBC 201 lrvalailkllkeell 216 ++v+la+lk +k el+ FUN_000285-T1 393 VFVCLAVLKEYKYELM 408 5799999999998876 PP >> RabGap-TBC_2 RabGAP TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.6 0.6 6e-13 5.1e-09 6 127 .. 235 353 .. 231 356 .. 0.88 2 ? -2.5 0.1 0.55 4.7e+03 34 69 .. 384 421 .. 380 438 .. 0.69 Alignments for each domain: == domain 1 score: 36.6 bits; conditional E-value: 6e-13 RabGap-TBC_2 6 kvlkaysLyDtevgYaqgllfiaaplllym.peeeaFsllvkLlkkydlrelfipdmpglelrLyqferlledllpalaihLqrqgvkssmyasqw 100 +l +ys y ++vgY+qg++ i + +l+ + +e ea+ +v+ ++ + f+ d g+ ++ q++ ll+ l +l+ h+q qg+ + w FUN_000285-T1 235 DILITYSAYHPDVGYVQGMNDILSRFLIVLgSETEAYWCFVNYMETV--KRDFLDD--GMLHKVEQVSVLLKRLDEHLYNHFQSQGMGDILFVHRW 326 68889****************9999998874789**********875..5667766..34456679****************************** PP RabGap-TBC_2 101 fltlFaykfpldlvlRifDlviaeGle 127 ++ F +fp ++l +f+++ ++ le FUN_000285-T1 327 LVLSFKREFPYGDALTMFEIISSQHLE 353 ********************9987665 PP == domain 2 score: -2.5 bits; conditional E-value: 0.55 RabGap-TBC_2 34 ympeeeaFsllvkL..lkkydlrelfipdmpglelrLy 69 m+ + F ++v+L lk+y+ + +++++++ ++++ FUN_000285-T1 384 DMNANYPFEVFVCLavLKEYKYELMKCSEVSSVYNTIH 421 56667778888887556777776666666666666555 PP >> Zwint ZW10 interactor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 2.9e-05 0.24 33 81 .. 88 134 .. 82 180 .. 0.77 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.9e-05 Zwint 33 dflqnflaqedtaqgldPlasedtsrqkaiaakeqwkelkatyqehvea 81 fl ++ t ++ + l +e+ +r +a+ k +wkel tyq ve+ FUN_000285-T1 88 SFLFGLFPFSSTRREREALGAENEARYQAL--KMRWKELVQTYQPPVES 134 677777777788999************998..778*********99996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (461 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 806 (0.0315522); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 4573.29 // Query: FUN_000286-T1 [L=295] Description: FUN_000286 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-79 267.7 7.8 1.5e-79 267.4 7.8 1.1 1 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal g ------ inclusion threshold ------ 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 COLFI Fibrillar collagen C-terminal domain 0.028 15.0 0.0 0.061 13.9 0.0 1.5 1 TolA_bind_tri TolA binding protein trimerisation 0.18 12.5 1.4 0.63 10.8 0.4 2.0 2 TPD52 Tumour protein D52 family Domain annotation for each model (and alignments): >> Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 267.4 7.8 2.3e-83 1.5e-79 2 220 .. 84 292 .. 83 293 .. 0.97 Alignments for each domain: == domain 1 score: 267.4 bits; conditional E-value: 2.3e-83 Fibrinogen_C 2 grdCedaakkGaktsglytitldkakkalevyCdmetdggGWtvlqkrldGstnfkreWkdykaGfGnlskeefWLGndkihkltkqgeyklridl 97 +r+C + +k G++ s +yti +d+ +++v+Cd +t ggGWtv+q rldGs+ f+r W+dyk+GfGnl+ +e+WLG dki +ltk ++ +lr+dl FUN_000286-T1 84 KRNCAELYKSGKRISAVYTIDPDGL-GPFNVFCDQKTAGGGWTVFQTRLDGSVSFYRGWSDYKRGFGNLN-GEYWLGLDKIYRLTKLKN-TLRVDL 176 69**********************9.9*******************************************.9**************987.69**** PP Fibrinogen_C 98 edfngetvfalydsfkvanekekyrLkvenykGdagdalktadksmtshngrvfstldrdndslsknCalsykggwWynkChaanlnGkyyygktk 193 ed +g+t++a y+ f va+e ky+L++++y+G+agd+l+ h g fst d+dnds s +Ca++ykg+wWy++Ch++nlnG y++gk+ FUN_000286-T1 177 EDTKGKTAYAAYEMFAVADERAKYKLNLGKYSGTAGDSLS-------GHRGAPFSTKDNDNDSRSSSCAVTYKGAWWYKSCHSSNLNGIYHHGKHS 265 *********************************7777665.......89*********************************************** PP Fibrinogen_C 194 skqnGivWatWkgseyslkkaemkirP 220 s +G++W +Wkg+ ys kkaemkirP FUN_000286-T1 266 SYADGVNWSHWKGFYYSAKKAEMKIRP 292 **************************9 PP >> COLFI Fibrillar collagen C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 8.4e-06 0.054 9 69 .. 59 119 .. 52 135 .. 0.75 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 8.4e-06 COLFI 9 lkslkkeie....elrsPeGskknpartCkdlklshpdlksgeyWiDPnqGcakDaikvyCnfet 69 l ++kk+++ ++++ +G+ k r+C +l+ s +++ s y iDP+ ++v+C+ +t FUN_000286-T1 59 LMKMKKQLSqiesDIKKLKGTVKAHKRNCAELYKSGKRI-SAVYTIDPDG---LGPFNVFCDQKT 119 4444444430002578889*************9998776.669*****96...457999999887 PP >> TolA_bind_tri TolA binding protein trimerisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 9.6e-06 0.061 19 51 .. 58 90 .. 53 98 .. 0.85 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 9.6e-06 TolA_bind_tri 19 allelqqqleqLqqevaeLRGqiEelqyqleql 51 +l+++ +ql+q+++++++L+G++ ++++ +l FUN_000286-T1 58 LLMKMKKQLSQIESDIKKLKGTVKAHKRNCAEL 90 6899******************99988877665 PP >> TPD52 Tumour protein D52 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.4 9.8e-05 0.63 8 39 .. 61 92 .. 56 100 .. 0.90 2 ? -0.3 0.0 0.27 1.7e+03 44 79 .. 163 197 .. 158 204 .. 0.79 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 9.8e-05 TPD52 8 elkseLakleeeivtLrqvLaakekhlaelkr 39 ++k+ L ++e +i+ L+ + a+++++ael + FUN_000286-T1 61 KMKKQLSQIESDIKKLKGTVKAHKRNCAELYK 92 799**************************965 PP == domain 2 score: -0.3 bits; conditional E-value: 0.27 TPD52 44 talselkqnlskswhdvqvsnaykktsetlsqagqk 79 l++lk+ l ++d + ++ay e ++ a + FUN_000286-T1 163 YRLTKLKNTLRVDLEDTKGKTAYAA-YEMFAVADER 197 5688999999999999999999965.7777777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1288 (0.0504208); expected 510.9 (0.02) Passed bias filter: 1066 (0.0417303); expected 510.9 (0.02) Passed Vit filter: 167 (0.00653748); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 2814.80 // Query: FUN_000286-T2 [L=295] Description: FUN_000286 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-80 269.1 8.2 5.5e-80 268.8 8.2 1.1 1 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal gl ------ inclusion threshold ------ 0.17 12.8 0.9 0.51 11.3 0.1 2.1 2 CHD1-like_C Chromodomain-helicase-DNA-binding protein 1-lik Domain annotation for each model (and alignments): >> Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 268.8 8.2 4.3e-84 5.5e-80 2 220 .. 84 292 .. 83 293 .. 0.97 Alignments for each domain: == domain 1 score: 268.8 bits; conditional E-value: 4.3e-84 Fibrinogen_C 2 grdCedaakkGaktsglytitldkakkalevyCdmetdggGWtvlqkrldGstnfkreWkdykaGfGnlskeefWLGndkihkltkqgeyklridl 97 +r+C + +k G++ s +yti +d+ +++v+Cd +t ggGWtv+qkrldGs+nf+r W+dyk+GfGnl+ +e+WLG dki +ltk ++ +lr+dl FUN_000286-T2 84 KRNCAELYKAGKRISAVYTIDPDGL-GPFDVFCDQKTAGGGWTVFQKRLDGSVNFYRGWSDYKRGFGNLN-GEYWLGLDKIYRLTKLKN-TLRVDL 176 69**********************9.9*******************************************.9**************987.69**** PP Fibrinogen_C 98 edfngetvfalydsfkvanekekyrLkvenykGdagdalktadksmtshngrvfstldrdndslsknCalsykggwWynkChaanlnGkyyygktk 193 ed +g++++a y+ f vane ky+L++++y+G+agd+l+ h g fst d+dnds s +Ca++ykg+wWy++Ch++nlnG y++gk+ FUN_000286-T2 177 EDTKGKSAYAAYEMFAVANERAKYKLNLGKYSGTAGDSLS-------GHRGAPFSTKDNDNDSRSSSCAVTYKGAWWYKSCHSSNLNGIYHHGKHS 265 *********************************7777665.......89*********************************************** PP Fibrinogen_C 194 skqnGivWatWkgseyslkkaemkirP 220 s +G++W +Wkg+ ys kkaemkirP FUN_000286-T2 266 SYADGVNWSHWKGFYYSAKKAEMKIRP 292 **************************9 PP >> CHD1-like_C Chromodomain-helicase-DNA-binding protein 1-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 4e-05 0.51 39 65 .. 58 84 .. 49 101 .. 0.80 2 ? -1.2 0.1 0.31 4e+03 75 96 .] 240 261 .. 223 261 .. 0.75 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 4e-05 CHD1-like_C 39 rakilkkeLlkiGdfIdeilkeskkek 65 + ++kk+L +iG++I+++ ++ k++k FUN_000286-T2 58 LLMKMKKQLSQIGSHIKTLKDTGKAHK 84 56899***********99999877333 PP == domain 2 score: -1.2 bits; conditional E-value: 0.31 CHD1-like_C 75 sfvskfwpkkvsskkLremYkk 96 ++ +w k+ s++L+ +Y++ FUN_000286-T2 240 TYKGAWWYKSCHSSNLNGIYHH 261 5666789988999999999985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 899 (0.0351928); expected 510.9 (0.02) Passed bias filter: 739 (0.0289293); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 2830.42 // Query: FUN_000286-T3 [L=296] Description: FUN_000286 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-77 260.4 7.1 2.5e-77 260.1 7.1 1.1 1 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal gl Domain annotation for each model (and alignments): >> Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 260.1 7.1 9.8e-82 2.5e-77 2 220 .. 84 293 .. 83 294 .. 0.96 Alignments for each domain: == domain 1 score: 260.1 bits; conditional E-value: 9.8e-82 Fibrinogen_C 2 grdCedaakkGaktsglytitldkakkalevyCdmetdggGWtvlqkrldGstnfkreWkdykaGfGnlskeefWLGndkihkltkqgeyklridl 97 +r+C + +k G++ s +yti +d+ +++v+Cd +t ggGWtv+qkrldGs+nf+r W+dyk+GfGnl+ +e+WLG dki +ltk ++ +lr+dl FUN_000286-T3 84 KRNCAELYKAGKRISAVYTIDPDGL-GPFDVFCDQKTAGGGWTVFQKRLDGSVNFYRGWSDYKRGFGNLN-GEYWLGLDKIYRLTKLKN-TLRVDL 176 69**********************9.9*******************************************.9**************987.69**** PP Fibrinogen_C 98 edfngetvfalydsfkvanekekyrLkvenykGdagdalktadksmtshngrvfstldrdnd.slsknCalsykggwWynkChaanlnGkyyygkt 192 ed +g++++a y+ f vane ky+L++++y+G+agd+l+ +h g fst d+dnd s+nCa+ ykg+wW++ Ch+++lnG y++gk+ FUN_000286-T3 177 EDTKGKSAYAAYEMFAVANERAKYKLNLGKYSGTAGDSLS-------HHRGAPFSTKDSDNDsWSSGNCAVLYKGAWWFRGCHSSHLNGIYHQGKH 265 *********************************7776665.......8**************44689***************************** PP Fibrinogen_C 193 kskqnGivWatWkgseyslkkaemkirP 220 s+ + ++W++Wkg+ ys k+aemkirP FUN_000286-T3 266 SSSAERVNWYHWKGHYYSAKRAEMKIRP 293 ***************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (296 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 876 (0.0342924); expected 510.9 (0.02) Passed bias filter: 726 (0.0284204); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2900.37 // Query: FUN_000288-T1 [L=450] Description: FUN_000288 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-74 250.0 4.5 7.1e-74 249.7 4.5 1.0 1 Adaptin_N Adaptin N terminal region 1.1e-07 32.5 0.9 8.2e-06 26.4 0.0 3.0 3 Cnd1 non-SMC mitotic condensation complex subunit 1 7.9e-07 29.8 0.1 0.00072 20.3 0.0 3.5 3 HEAT_2 HEAT repeats 1.7e-06 28.2 0.3 0.058 14.2 0.0 4.4 3 HEAT HEAT repeat 5.7e-05 23.8 1.8 0.0019 18.8 0.9 2.8 3 HEAT_GCN1 Stalled ribosome sensor GCN1-like, HEAT repeat 0.00012 22.8 3.3 0.3 11.7 0.0 3.1 3 ParcG Parkin co-regulated protein 0.00067 20.3 0.0 0.86 10.4 0.0 3.6 4 SCD Stromalin conservative domain 0.0014 19.6 0.9 0.0041 18.1 0.2 2.2 1 HEAT_EZ HEAT-like repeat 0.0097 16.8 1.7 6.5 7.7 0.5 3.1 3 EFR3_ARM EFR3, armadillo repeat ------ inclusion threshold ------ 0.016 15.6 0.8 0.016 15.6 0.8 1.7 2 STN1_2 CST, complex subunit STN1, C terminal 0.025 14.6 0.8 0.12 12.4 0.3 2.3 3 CLASP_N CLASP N terminal 0.035 14.9 0.3 1.5 9.6 0.1 2.6 2 IFNGR1_transm Interferon gamma receptor 1, transmembrane reg 0.16 12.2 0.0 60 4.0 0.0 3.4 3 PheRS_DBD1 PheRS DNA binding domain 1 Domain annotation for each model (and alignments): >> Adaptin_N Adaptin N terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 249.7 4.5 3.6e-77 7.1e-74 4 370 .. 46 436 .. 43 444 .. 0.92 Alignments for each domain: == domain 1 score: 249.7 bits; conditional E-value: 3.6e-77 Adaptin_N 4 tiqqelaeilnsfk...ddprkkkeavkkllylimlGedvsflffevvklvaskdfelKrlvYlylkelaeesedlaiLvtnslkkDlqspnqlir 96 +i +el ++++ ++++ +e++ +l+y +mlG+dvs++ +e++k+ + + +Kr++Yl+++++++e+++l+ L +n+l+kDl+s n + + FUN_000288-T1 46 IIVKELGLLKDKLTqrdLSKKEMRENLVRLIYCQMLGHDVSSGYVEAIKFAEQQSTLDKRVGYLAASLFLHEDHELIVLLINTLQKDLKSTNVMEV 141 5666666666666555578888999*********************************************************************** PP Adaptin_N 97 glALrtLskirspelaedlaraikkllvdrspyVrkkAalailklyrkspelvekfveelkellsdkdpgVvsaAvalleei.kkndklllkllpk 191 + AL++ +k++ ++++++l++++ +ll+++++ VrkkA++a+ y ksp+ +++ e+ k+++ dkdpgV a ++++ e+ k ++ + ++l+p FUN_000288-T1 142 CCALTVVCKLINKDMMPALLPQVLQLLQSKRDIVRKKAVMALHSFYIKSPSSIPDLKEHAKKAIMDKDPGVMCASLQVFNELiKASPTECKDLVPA 237 **********************************************************************************999999988***** PP Adaptin_N 192 lvrrlknll...........gelnpwlqvkilrllsrlarqdpeeskkelledilnllq......ssnnaVlletvktivelasesellvlavnaL 270 +v+ k ++ g+++pw+qvk+lr+l l++ d+++s+ +++ + l + aV +e+ +ti+ + ++ l+ +a+++ FUN_000288-T1 238 FVSLQKMIVegklapeydyhGVSSPWIQVKLLRMLGLLGADDQRASQ-KMYSVLGRTLTnlntnsLISYAVAYECTRTITAIYPDKGLIGKAAKCV 332 ***977666*********************************99995.4544444444433355545789************************** PP Adaptin_N 271 vrllsssdenlryvaLrtlnkivekepkavq...hkdlkleclktdddisirlralelllklvnesNvkeivkeLkkyvsevaded..fkselvka 361 + +l + + ++yv ++tl +++ v+ + ++++cl+ d+d+ ++++l+ll ++n sNv+ + ++L+++++++ d d f++elv+ FUN_000288-T1 333 GIFLVAKTNDIKYVGITTLTSLLQVGSGFVMesaYQRFVIDCLD-DPDETLKRKTLDLLCHITNASNVETVCEKLLSFLKSTTDVDtyFRAELVDR 427 *************************98888865457899*****.**********************************999999999******** PP Adaptin_N 362 Igslaekfa 370 I +lae+++ FUN_000288-T1 428 ITELAERYP 436 *******96 PP >> Cnd1 non-SMC mitotic condensation complex subunit 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.2 0.095 1.9e+02 19 54 .. 122 157 .. 112 160 .. 0.81 2 ! 26.4 0.0 4.2e-09 8.2e-06 6 151 .. 144 300 .. 142 309 .. 0.86 3 ? 2.7 0.0 0.085 1.7e+02 64 102 .. 372 408 .. 342 434 .. 0.59 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.095 Cnd1 19 veylvepLrkrLkDedpyVRktAaivvakLilndmv 54 + l++ L+k Lk ++++ A+ vv+kLi++dm+ FUN_000288-T1 122 IVLLINTLQKDLKSTNVMEVCCALTVVCKLINKDMM 157 5567778888888888887788999********997 PP == domain 2 score: 26.4 bits; conditional E-value: 4.2e-09 Cnd1 6 airtlgcirvpnlveylvepLrkrLkDedpyVRktAaivvakLilndmvkvkgflselaklLeDenprVvanalaalteiseksenaiynllpdii 101 a+ ++ + ++++ +l++++ + L+ + VRk+A++++ + + ++ ++ +k++ D++p V+ +l +++e+ + s++ l+p + FUN_000288-T1 144 ALTVVCKLINKDMMPALLPQVLQLLQSKRDIVRKKAVMALHSFYIKSPSSIPDLKEHAKKAIMDKDPGVMCASLQVFNELIKASPTECKDLVPAFV 239 566667777788999999*************************999**********************************************9999 PP Cnd1 102 sklsdalne...........csewgqktileaLlsyipkdkqeaeslveklcprlqhansa 151 s ++ + s w q++ l++L + ++d++ ++++ l l++ n+ FUN_000288-T1 240 SLQKMIVEGklapeydyhgvSSPWIQVKLLRMLGLLGADDQRASQKMYSVLGRTLTNLNTN 300 9888644436677788888899999999999999999999997777777777777666655 PP == domain 3 score: 2.7 bits; conditional E-value: 0.085 Cnd1 64 aklLeDenprVvanalaalteiseksenaiynllpdiis 102 ++L+D++++ +l +l+ i++ s ++ ++ ++++s FUN_000288-T1 372 IDCLDDPDETLKRKTLDLLCHITNAS--NVETVCEKLLS 408 44555555555555555555555544..23333333333 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 3.6e-07 0.00072 29 73 .. 157 203 .. 143 234 .. 0.88 2 ? -1.7 0.0 2.6 5.2e+03 14 31 .. 262 279 .. 260 308 .. 0.57 3 ? 5.1 0.0 0.02 40 4 40 .. 371 410 .. 369 431 .. 0.74 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 3.6e-07 HEAT_2 29 dpealpaLlellkdedpavRraaakaLgki..gdpealpaLlellad 73 p+ lp +l+ll+++ vR+ a++aL ++ ++p ++p L+e++++ FUN_000288-T1 157 MPALLPQVLQLLQSKRDIVRKKAVMALHSFyiKSPSSIPDLKEHAKK 203 5788999********************9876689********99875 PP == domain 2 score: -1.7 bits; conditional E-value: 2.6 HEAT_2 14 pevraaairaLgeigdpe 31 p ++ +r+Lg +g ++ FUN_000288-T1 262 PWIQVKLLRMLGLLGADD 279 555666666666333221 PP == domain 3 score: 5.1 bits; conditional E-value: 0.02 HEAT_2 4 LlqaLlkdpdpevraaairaLgeigdp....ealpaLlell 40 +++ L +dpd+ +++ + L++i ++ ++ + Ll++l FUN_000288-T1 371 VIDCL-DDPDETLKRKTLDLLCHITNAsnveTVCEKLLSFL 410 67889.9***************8877622224455555555 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 3e-05 0.058 1 27 [. 160 186 .. 160 189 .. 0.94 2 ? 4.6 0.0 0.037 72 7 29 .. 203 225 .. 199 227 .. 0.89 3 ? 4.2 0.0 0.049 96 4 28 .. 370 394 .. 369 397 .. 0.89 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 3e-05 HEAT 1 llplllkllnDpspeVReaAaeaLgal 27 llp +l+ll+++ + VR+ A+ aL ++ FUN_000288-T1 160 LLPQVLQLLQSKRDIVRKKAVMALHSF 186 79**********************987 PP == domain 2 score: 4.6 bits; conditional E-value: 0.037 HEAT 7 kllnDpspeVReaAaeaLgalae 29 k+++D++p V +a+++ + +l++ FUN_000288-T1 203 KAIMDKDPGVMCASLQVFNELIK 225 6789***************9987 PP == domain 3 score: 4.2 bits; conditional E-value: 0.049 HEAT 4 lllkllnDpspeVReaAaeaLgala 28 +++ +l Dp++ ++ ++ L++++ FUN_000288-T1 370 FVIDCLDDPDETLKRKTLDLLCHIT 394 5789*****************9986 PP >> HEAT_GCN1 Stalled ribosome sensor GCN1-like, HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 2.1 4.1e+03 18 36 .. 23 41 .. 17 76 .. 0.69 2 ! 18.8 0.9 9.6e-07 0.0019 41 156 .. 122 230 .. 110 247 .. 0.82 3 ? 2.3 0.0 0.11 2.2e+02 64 98 .. 385 418 .. 367 444 .. 0.69 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 2.1 HEAT_GCN1 18 nakaLasLaevaGeaLnrh 36 + +a +sL++++Gea ++h FUN_000288-T1 23 SSRAFQSLVRAIGEAKSKH 41 5677778888877776655 PP == domain 2 score: 18.8 bits; conditional E-value: 9.6e-07 HEAT_GCN1 41 lpaLlsalseeeeedeeeeeeleeaaeavvlsvedeegvrllieeLlealksedasrraaaakllgafcketkadyseyvpdllrelisllndede 136 + L+++l+++ + + + e+ a++ vv++ +++ + l+ ++l+ l+s++ +r+ a+ l++f ++ + +pdl ++ + +d+d+ FUN_000288-T1 122 IVLLINTLQKDLK--STNVMEVCCALT-VVCKLINKDMMPALLPQVLQLLQSKRDIVRKKAVMALHSFYIKS----PSSIPDLKEHAKKAIMDKDP 210 5567788887663..333467888888.555555555********************************999....66899*************** PP HEAT_GCN1 137 eVlkaawealsaltkkldke 156 V+ a+ + +++l+k+ + e FUN_000288-T1 211 GVMCASLQVFNELIKASPTE 230 ***************98754 PP == domain 3 score: 2.3 bits; conditional E-value: 0.11 HEAT_GCN1 64 eaaeavvlsvedeegvrllieeLlealksedasrr 98 ++++ +++++++ + v++++e+Ll+ lks++ FUN_000288-T1 385 KTLD-LLCHITNASNVETVCEKLLSFLKSTTDVDT 418 3444.888899999999999999999888654444 PP >> ParcG Parkin co-regulated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 1.5 0.0014 2.7 78 136 .. 122 178 .. 116 197 .. 0.83 2 ! 11.7 0.0 0.00015 0.3 78 128 .. 194 244 .. 189 253 .. 0.86 3 ? -0.2 0.0 0.69 1.4e+03 89 125 .. 375 413 .. 337 431 .. 0.79 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0014 ParcG 78 lpklilplkkaLntrdeeviesaLkvlqklvksseligeaLvpyyrqlLpvlnlfknkr 136 + li l+k+L++++ ++ aL+v+ kl +++ + +aL p + qlL+ + + +k+ FUN_000288-T1 122 IVLLINTLQKDLKSTNVMEVCCALTVVCKL--INKDMMPALLPQVLQLLQSKRDIVRKK 178 667999************************..6677789**********9877655555 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00015 ParcG 78 lpklilplkkaLntrdeeviesaLkvlqklvksseligeaLvpyyrqlLpv 128 +p l kka+ +d+ v++++L+v ++l+k+s++ + Lvp + l ++ FUN_000288-T1 194 IPDLKEHAKKAIMDKDPGVMCASLQVFNELIKASPTECKDLVPAFVSLQKM 244 5666666799*********************************88776555 PP == domain 3 score: -0.2 bits; conditional E-value: 0.69 ParcG 89 LntrdeeviesaLkvlqklvkss..eligeaLvpyyrql 125 L+ de+ ++L++l ++ ++s e++ e+L ++++ FUN_000288-T1 375 LDDPDETLKRKTLDLLCHITNASnvETVCEKLLSFLKST 413 677788888899999999988772246999999999865 PP >> SCD Stromalin conservative domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.018 34 38 68 .. 167 198 .. 163 204 .. 0.79 2 ? -2.0 0.0 3.3 6.4e+03 38 60 .. 204 226 .. 198 232 .. 0.80 3 ! 10.4 0.0 0.00044 0.86 6 66 .. 342 402 .. 337 412 .. 0.85 4 ? -1.9 0.0 2.9 5.7e+03 2 23 .. 415 436 .. 414 438 .. 0.75 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.018 SCD 38 lLsDksaevRlealkaLqkly.kneelvakle 68 lL+ k++ vR++a++aL+++y k+++ ++ l+ FUN_000288-T1 167 LLQSKRDIVRKKAVMALHSFYiKSPSSIPDLK 198 68899999************944556666665 PP == domain 2 score: -2.0 bits; conditional E-value: 3.3 SCD 38 lLsDksaevRlealkaLqklykn 60 ++ Dk++ v ++l++ ++l+k FUN_000288-T1 204 AIMDKDPGVMCASLQVFNELIKA 226 57899999999999999888875 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00044 SCD 6 eIRaecieelgeWikkypekFledsylrYlgwlLsDksaevRlealkaLqklykneelvak 66 +I+ i+ l++ ++ + + +e+ y r++ +L D++++ ++++l+ L ++ + +++ + FUN_000288-T1 342 DIKYVGITTLTSLLQVGSGFVMESAYQRFVIDCLDDPDETLKRKTLDLLCHITNASNVETV 402 788889999999999999999*****************************99987665543 PP == domain 4 score: -1.9 bits; conditional E-value: 2.9 SCD 2 DvdpeIRaecieelgeWikkyp 23 Dvd Rae ++ ++e ++yp FUN_000288-T1 415 DVDTYFRAELVDRITELAERYP 436 7888888888888887777776 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.2 2.1e-06 0.0041 10 52 .. 144 183 .. 139 185 .. 0.89 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 2.1e-06 HEAT_EZ 10 aLGslaeggpdllapllpellplLlplLnddddeVReaAawaL 52 aL ++++ + +++ p llp+ l+lL++++d VR++A+ aL FUN_000288-T1 144 ALT---VVCKLINKDMMPALLPQVLQLLQSKRDIVRKKAVMAL 183 563...67899999**************************998 PP >> EFR3_ARM EFR3, armadillo repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.5 0.0033 6.5 13 80 .. 127 187 .. 122 193 .. 0.75 2 ! 6.3 0.0 0.0087 17 11 64 .. 197 249 .. 195 261 .. 0.84 3 ? -2.1 0.0 3.6 7.2e+03 69 91 .. 399 421 .. 385 423 .. 0.68 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0033 EFR3_ARM 13 qrlsrdlyrertkyvkisiealdkLLlackaqslnlfvesyLkmvkkLLeskeeelqilatesfvkFs 80 + l++dl+ + v+ ++ ++ kL+ + ++ +L v +LL+sk++ +++ a+ ++ +F FUN_000288-T1 127 NTLQKDLKSTNVMEVCCALTVVCKLINKD-------MMPALLPQVLQLLQSKRDIVRKKAVMALHSFY 187 55666666666666666666666666543.......56789999999*************99999985 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0087 EFR3_ARM 11 LaqrlsrdlyrertkyvkisiealdkLLlackaqslnlfvesyLkmvkkLLesk 64 L ++ ++++ + + ++ s++++++L++a+ ++ + +v ++++ k+++e k FUN_000288-T1 197 LKEHAKKAIMDKDPGVMCASLQVFNELIKASPTE-CKDLVPAFVSLQKMIVEGK 249 66788999999999*****************888.7889999999888887765 PP == domain 3 score: -2.1 bits; conditional E-value: 3.6 EFR3_ARM 69 qilatesfvkFseieedtpsyer 91 + +e + +F ++ d +y r FUN_000288-T1 399 VETVCEKLLSFLKSTTDVDTYFR 421 34567888888888888888876 PP >> STN1_2 CST, complex subunit STN1, C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.8 8.3e-06 0.016 92 158 .. 114 176 .. 52 187 .. 0.80 2 ? -3.9 0.0 7.8 1.5e+04 142 156 .. 402 416 .. 396 433 .. 0.52 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 8.3e-06 STN1_2 92 vteqdkdLlkkikdiikedckkekyaEkGChllhilscvrqsyspnlseavlqqvlelLEdnSdivs 158 ++d++L + +++++d k ++ +E C l+ + + +++ + a l qvl+lL ++ div FUN_000288-T1 114 FLHEDHELIVLLINTLQKDLKSTNVMEVCCALTVVCKLINKD----MMPALLPQVLQLLQSKRDIVR 176 4579**************************998877776655....5567799************95 PP == domain 2 score: -3.9 bits; conditional E-value: 7.8 STN1_2 142 vlqqvlelLEdnSdi 156 v +++l++L + d+ FUN_000288-T1 402 VCEKLLSFLKSTTDV 416 344444444444443 PP >> CLASP_N CLASP N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 1.2 2.3e+03 12 84 .. 54 129 .. 48 146 .. 0.69 2 ? 12.4 0.3 6.1e-05 0.12 64 162 .. 132 228 .. 114 248 .. 0.76 3 ? -0.9 0.0 0.72 1.4e+03 175 196 .. 365 386 .. 331 414 .. 0.79 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.2 CLASP_N 12 fegketeqnwdaReksilklrslikgnapedfvsellealk..sllegilkavsslrttlsstgch.Llkelaiql 84 + +k t + +++e +r + + +d++s ++ea+k + ++ + k v l ++l+ + h L+ l +l FUN_000288-T1 54 LKDKLTQRDLSKKEMRENLVRLIYCQMLGHDVSSGYVEAIKfaEQQSTLDKRVGYLAASLFLHEDHeLIVLLINTL 129 6677788888888888888888888889999999999999966566666667777777776655432444444444 PP == domain 2 score: 12.4 bits; conditional E-value: 6.1e-05 CLASP_N 64 slrttlsstgchLlkelaiqlgealdplveillptLlkllgdtKkitsqnanvavaallsnasys.srilqvlsvalqdKNvqpRefsaiWlkill 158 +l +t +++ c l+ +++ ++ ++ +llp++l+ll + ++i++++a +a+ +++ +++ s +++ +++ a+ dK + + ++s++ + l+ FUN_000288-T1 132 DLKSTNVMEVCCALTVVCKLINK---DMMPALLPQVLQLLQSKRDIVRKKAVMALHSFYIKSPSSiPDLKEHAKKAIMDKDPGVMCASLQVFNELI 224 55556666666666655555555...577799**************************999886537889**********9999888888777777 PP CLASP_N 159 krhg 162 k ++ FUN_000288-T1 225 KASP 228 7666 PP == domain 3 score: -0.9 bits; conditional E-value: 0.72 CLASP_N 175 dliekslkkgLeDanpeVReta 196 ++++ ++ +L D++++ ++++ FUN_000288-T1 365 SAYQRFVIDCLDDPDETLKRKT 386 5688889999999998877655 PP >> IFNGR1_transm Interferon gamma receptor 1, transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.1 0.00078 1.5 6 28 .. 186 208 .. 183 209 .. 0.93 2 ? 2.5 0.0 0.13 2.5e+02 3 19 .. 332 348 .. 330 357 .. 0.80 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00078 IFNGR1_transm 6 yiiKkrndlervkirlkrvvssk 28 ++iK++++++++k+ k+++ +k FUN_000288-T1 186 FYIKSPSSIPDLKEHAKKAIMDK 208 69*****************9987 PP == domain 2 score: 2.5 bits; conditional E-value: 0.13 IFNGR1_transm 3 VdiyiiKkrndlervki 19 V i+ + k nd+++v i FUN_000288-T1 332 VGIFLVAKTNDIKYVGI 348 668878899*****976 PP >> PheRS_DBD1 PheRS DNA binding domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.12 2.3e+02 24 43 .. 111 130 .. 105 132 .. 0.83 2 ? 4.0 0.0 0.031 60 41 58 .. 216 233 .. 213 234 .. 0.90 3 ? 1.4 0.0 0.2 3.9e+02 4 22 .. 401 419 .. 398 426 .. 0.85 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.12 PheRS_DBD1 24 lAaelgvdHqkiVGaiKSLq 43 ++ l +dH+ iV i+ Lq FUN_000288-T1 111 ASLFLHEDHELIVLLINTLQ 130 455689*******9999887 PP == domain 2 score: 4.0 bits; conditional E-value: 0.031 PheRS_DBD1 41 SLqAlgevikaeqrtskk 58 SLq ++e+ika + ++k FUN_000288-T1 216 SLQVFNELIKASPTECKD 233 9***********999986 PP == domain 3 score: 1.4 bits; conditional E-value: 0.2 PheRS_DBD1 4 dltekiLqrlekkgevdsl 22 ++ek+L l ++ vd++ FUN_000288-T1 401 TVCEKLLSFLKSTTDVDTY 419 689**************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (450 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 869 (0.0340184); expected 510.9 (0.02) Passed bias filter: 650 (0.0254453); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4441.37 // Query: FUN_000289-T1 [L=725] Description: FUN_000289 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-20 72.0 0.0 1e-19 71.1 0.0 1.5 1 AP4E_app_platf Adaptin AP4 complex epsilon appendage platfo 2.7e-07 30.0 0.0 3.7e-07 29.6 0.0 1.1 1 Adaptin_N Adaptin N terminal region ------ inclusion threshold ------ 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 Coatomer_b_Cpla Coatomer beta subunit appendage platform 0.25 12.0 0.0 14 6.4 0.0 2.4 2 DUF6074 Family of unknown function (DUF6074) Domain annotation for each model (and alignments): >> AP4E_app_platf Adaptin AP4 complex epsilon appendage platform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.1 0.0 1.6e-23 1e-19 1 99 [. 625 722 .. 625 723 .. 0.96 Alignments for each domain: == domain 1 score: 71.1 bits; conditional E-value: 1.6e-23 AP4E_app_platf 1 PltisteefgklWlslsserkqnlkssqvstlsel.nalkeklrlhvVevignElIvAgqllssskvvllhvklsagaldvklrskdkeladvvl 94 Pl i+teefg +W + s+e++q++ s+ + +e+ ++ +++l++ +Ve+ig +I+Ag+l++s ++llh++ ++++l+++++s+ l d+v+ FUN_000289-T1 625 PLVINTEEFGLKWTDASFEKRQKMF-SSSRNCQEFsKRAEQELNIYTVEMIGGKAILAGTLMESG-ICLLHASCDGDSLELSIKSNNRLLNDAVI 717 99***********************.6678889999*****************************.***************************** PP AP4E_app_platf 95 kalqk 99 k++ + FUN_000289-T1 718 KHCVT 722 ***75 PP >> Adaptin_N Adaptin N terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.0 5.8e-11 3.7e-07 409 522 .. 37 148 .. 32 150 .. 0.80 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 5.8e-11 Adaptin_N 409 lreyivekLcelletieseea.kaaalWilGeygelisn..te.sasdllrsilekfvlesakvraaaltalvKlsltspdeelqesiiqlllsla 500 r+++v ++lle+ + + ++++ W+lGey+ +s+ e ++++l+ ++le+ ++ + ++a +++a+ Kl + + s+ ++l+++a FUN_000289-T1 37 IRRFAVVSYMDLLEKTVLPDIlVRVICWVLGEYSYTASEyePEvILEELI-TLLERKFEDPG-TKAWVVSAIGKLMSQMG--QPVGSMRDVLEKYA 128 5666666677888887777743999*************986554555555.55666666666.8************9997..5778********** PP Adaptin_N 501 tqdssdlevrdRaveylqllss 522 + + d+e+r+R+ e+ +l ++ FUN_000289-T1 129 S--AVDVELRQRSLEIDKLSKN 148 *..*************999875 PP >> Coatomer_b_Cpla Coatomer beta subunit appendage platform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 3.9e-05 0.25 12 67 .. 617 672 .. 611 706 .. 0.90 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 3.9e-05 Coatomer_b_Cpla 12 idimdyikpakiseeeFremWaefeWEnkitvktklsdlkeyleelvkktnmkllt 67 + + d ++p i++eeF +W+ E++ ++ ++ ++ +e+ ++ +++n+ ++ FUN_000289-T1 617 LSVKDILRPLVINTEEFGLKWTDASFEKRQKMFSSSRNCQEFSKRAEQELNIYTVE 672 5688***********************************************99887 PP >> DUF6074 Family of unknown function (DUF6074) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.028 1.8e+02 42 65 .. 18 41 .. 8 49 .. 0.82 2 ? 6.4 0.0 0.0022 14 39 76 .. 102 139 .. 87 144 .. 0.86 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.028 DUF6074 42 alaaeLarlGlseeeireevlaFq 65 ++++ G +ee++++e+++F+ FUN_000289-T1 18 HNLMRFLAEGTDEEDADNEIRRFA 41 555677889**************6 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0022 DUF6074 39 ecralaaeLarlGlseeeireevlaFqdaVqaelerls 76 ++ a+ + ++++G + +r+ ++++++aV++el+++s FUN_000289-T1 102 VVSAIGKLMSQMGQPVGSMRDVLEKYASAVDVELRQRS 139 57889999**************************9886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (725 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 825 (0.0322959); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6937.86 // Query: FUN_000290-T1 [L=307] Description: FUN_000290 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.029 14.9 0.0 0.15 12.6 0.0 2.1 2 DUF1836 Domain of unknown function (DUF1836) Domain annotation for each model (and alignments): >> DUF1836 Domain of unknown function (DUF1836) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.098 2.5e+03 7 26 .. 116 135 .. 112 160 .. 0.62 2 ? 12.6 0.0 6e-06 0.15 33 90 .. 202 260 .. 188 279 .. 0.87 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.098 DUF1836 7 PeidLyldqvielinkkles 26 P +++y++q+i+ i ++ + FUN_000290-T1 116 PAYGVYISQLIAKIIQTSQF 135 67788888887766555443 PP == domain 2 score: 12.6 bits; conditional E-value: 6e-06 DUF1836 33 kkltktminnYvKekliskpkk.KkYskeqiaelilisllksvlsleeikkllklalee 90 k++++t + +vK++ i + + KkY+ ++ + l +i + + v ++ +++k ++++l++ FUN_000290-T1 202 KVFKSTLMPMFVKRDTIVDTLHtKKYKLQEEIGLEFIHNGQLVAAFTHVEKHIRFLLKQ 260 78999*********998877666****************************99998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (307 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 922 (0.0360932); expected 510.9 (0.02) Passed bias filter: 616 (0.0241143); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3056.86 // Query: FUN_000291-T1 [L=114] Description: FUN_000291 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (114 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 418 (0.0163633); expected 510.9 (0.02) Passed bias filter: 347 (0.0135839); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1174.16 // Query: FUN_000292-T1 [L=272] Description: FUN_000292 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 329 (0.0128792); expected 510.9 (0.02) Passed bias filter: 176 (0.0068898); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2743.18 // Query: FUN_000293-T1 [L=99] Description: FUN_000293 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 437 (0.0171071); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1002.41 // Query: FUN_000294-T1 [L=86] Description: FUN_000294 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (86 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 269 (0.0105304); expected 510.9 (0.02) Passed bias filter: 205 (0.00802505); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 868.68 // Query: FUN_000295-T1 [L=864] Description: FUN_000295 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.9e-34 116.1 14.9 1.7e-10 41.5 0.1 3.5 3 fn3 Fibronectin type III domain 1.6e-26 92.8 13.4 7.1e-15 55.5 3.9 2.8 2 D8C_UMOD Uromodulin-like, D8C domain 1.2e-08 35.6 2.8 0.095 13.5 0.0 4.1 4 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 4.5e-06 27.7 18.0 0.035 15.2 0.5 3.9 3 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 5.1e-05 24.0 0.1 0.00013 22.7 0.1 1.8 1 CUB CUB domain 5.4e-05 23.8 3.0 1.1 10.0 0.3 4.1 3 fn3_2 Fibronectin type III domain 0.0026 18.7 0.0 16 6.5 0.1 3.6 3 Glyco_hydro_36C Glycosyl hydrolase family 36 C-terminal d Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.4 1.2 4.7e-14 1.7e-10 2 77 .. 135 220 .. 134 227 .. 0.86 2 ! 41.5 0.1 4.6e-14 1.7e-10 2 82 .. 619 706 .. 618 708 .. 0.85 3 ! 40.5 2.2 9.3e-14 3.4e-10 2 80 .. 757 843 .. 756 847 .. 0.87 Alignments for each domain: == domain 1 score: 41.4 bits; conditional E-value: 4.7e-14 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp...kne.....tvpgsretsvtltgLkpgteYevrVqavngaGegee 77 +P n++ ++ +sts+ v+W++ +ng i Y+v y+ +++ v + +t+ tltgL++g Y+++V a n +G+g+ FUN_000295-T1 135 PPANVRGSRMSSTSIFVQWDQVpsqYQNGVILYYTVAYYRryySSSfpqrvVVAAP-TTQTTLTGLNQGALYTISVSASNIRGDGPV 220 899*****************9999999*********99986653347776666666.9**************************964 PP == domain 2 score: 41.5 bits; conditional E-value: 4.6e-14 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ +++sts+ v+W++ ++ng + Y+v+yr + v s +++ ltgL+ +t+Y+++V a + + +g s+p+ FUN_000295-T1 619 PPANVSGYNISSTSIFVQWDHVpaaHQNGAMLYYTVTYRALPSglrqtvVVAAS-AHQTRLTGLNKYTNYSITVFASTCK-DGNVSAPIF 706 899******************99**9**************55545665555555.899*****************95554.888888875 PP == domain 3 score: 40.5 bits; conditional E-value: 9.3e-14 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne.......tvpgsretsvtltgLkpgteYevrVqavngaGegeesep 80 +P n++ + tsts+ v+W++ +ng i Y+v+y+ ++ v + +t+ tltgL+ +t Y+++V a + +G+g +s+ FUN_000295-T1 757 PPANVRG-NSTSTSIFVQWDQVppqYQNGVILYYTVTYYRAHYvrfrqrvVVFAP-TTQTTLTGLNHNTLYRITVSASTIKGDGYYSRI 843 8999999.***********98778*99************9666666665555555.899*************************99976 PP >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.0 2.0 3e-14 1.1e-10 4 76 .. 388 463 .. 385 474 .. 0.83 2 ! 55.5 3.9 1.9e-18 7.1e-15 9 87 .. 522 601 .. 515 602 .. 0.86 Alignments for each domain: == domain 1 score: 42.0 bits; conditional E-value: 3e-14 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyef 76 f g qm ++c sc tn+ wl g hpt+ +g+v r++c +++ +cc q++ i v+ c g fyvy + FUN_000295-T1 388 FSGGAGTQMAEACPKMYSCSTNSSGWLNGSHPTVAEGIVKRKVCflqlvSQFLTDCC-NQAKTISVRNC-GAFYVYRL 463 6678999***********************************994443345667788.599*******9.89****85 PP == domain 2 score: 55.5 bits; conditional E-value: 1.9e-18 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyef..vrp.ttcnlayc 87 qm dtcv cg+ p wlsgghp+l dg v r++c cc + s i v+ c gfy+y++ v p +c+ yc FUN_000295-T1 522 GTQMADTCVSMRHCGARYPGWLSGGHPSLSDGAVLRKVCFTGNRGCCQY-STFISVRNCN-GFYIYKLstVYPyNSCDYRYC 601 57*************************************9999999987.789******7.69**98733566357999999 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.4 8.9e+03 52 79 .. 24 52 .. 6 55 .. 0.75 2 ! 13.5 0.0 2.6e-05 0.095 17 70 .. 162 217 .. 144 230 .. 0.73 3 ! 9.0 0.0 0.00068 2.5 17 65 .. 646 694 .. 628 712 .. 0.83 4 ! 10.4 0.1 0.00025 0.91 19 69 .. 785 836 .. 765 850 .. 0.83 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.4 FN3_DSCAM-DSCAML_C 52 LkpatwYe.lkvtAhneaGsteaeyefaT 79 L +a Y+ l++tA + G +++ + aT FUN_000295-T1 24 LPSAAAYSpLTITASPKTGEQTQGTSSAT 52 66677776599999999999999888877 PP == domain 2 score: 13.5 bits; conditional E-value: 2.6e-05 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkk.geeewil.vsnnkeqeklviedLkpatwYelkvtAhneaGs 70 + il+++v y ++ ++++ + v +++++++++++L+++ Y+++v+A n G FUN_000295-T1 162 NGVILYYTVAYYRRyYSSSFPQrVVVAAPTTQTTLTGLNQGALYTISVSASNIRGD 217 4569999999765514555554255678999*********************9886 PP == domain 3 score: 9.0 bits; conditional E-value: 0.00068 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAh 65 + +l+++v yr + ++v +++++++ +++L+ t Y+++v A FUN_000295-T1 646 NGAMLYYTVTYRALPSGLRQTVVVAASAHQTRLTGLNKYTNYSITVFAS 694 45799********999999999889999999***************986 PP == domain 4 score: 10.4 bits; conditional E-value: 0.00025 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvs.nnkeqeklviedLkpatwYelkvtAhneaG 69 il+++v y +++ ++ + ++++++++++L+ t Y+++v+A G FUN_000295-T1 785 VILYYTVTYYRAHYVRFRQRVvVFAPTTQTTLTGLNHNTLYRITVSASTIKG 836 699*****99999888887551568999*******************98766 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 1.0 0.00045 1.6 11 82 .. 145 213 .. 136 223 .. 0.72 2 ! 15.2 0.5 9.7e-06 0.035 10 82 .. 627 695 .. 620 709 .. 0.76 3 ! 10.9 3.4 0.00021 0.76 10 82 .. 764 833 .. 758 847 .. 0.77 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00045 Pur_ac_phosph_N 11 pstsmtvsWrtpe.attspvvqygtsssa...lsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 +sts+ v+W + + + ++ v+ y t +ss+++ + + +++ tltgL+ g Y +v ++n FUN_000295-T1 145 SSTSIFVQWDQVPsQYQNGVILYYTVAYYrryYSSSFP-------QRVVVAAPTTQTTLTGLNQGALYTISVSASN 213 5999*****99762557777777777644122333333.......3444678899*****************9887 PP == domain 2 score: 15.2 bits; conditional E-value: 9.7e-06 Pur_ac_phosph_N 10 g.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +sts+ v+W +++++++++y+ +++al s +t+++ + h+ +ltgL+ t+Y +v +++ FUN_000295-T1 627 NiSSTSIFVQWDHVpaAHQNGAMLYYTVTYRALPSGLRQTVVV-------AASAHQTRLTGLNKYTNYSITVFAST 695 5579*******99743466888999999998888877666664.......4678*****************96654 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00021 Pur_ac_phosph_N 10 g.pstsmtvsWrtpe.attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +sts+ v+W + + + ++ v+ y t + + + ++++ + +++ tltgL+ +t Y +v +++ FUN_000295-T1 764 NsTSTSIFVQWDQVPpQYQNGVILYYTVTYYRAHYVRFRQRVV-----VFAPTTQTTLTGLNHNTLYRITVSAST 833 4589*********863558889999999877666655444444.....5678999****************8875 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.1 3.6e-08 0.00013 13 110 .] 241 341 .. 229 341 .. 0.81 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 3.6e-08 CUB 13 sspnypkeYeenkeCvweirvekgksvklkfedfeleeeee.caydyvevrdgeeasskllgkfcG..sekpediksssnqllikfvsdesvskkG 105 + + Y+ + C w+i ++kg++vkl +++ + + c ++e+++g a+ +++ ++c ++k + ++ ++ l i+ ++s s+ FUN_000295-T1 241 GEIIFYRYYRYYQICSWKIMANKGEQVKLLLKSVNFPWCSFsCSCGQLEIQNGTYADGSAITRMCStlRGKVTIYSHVGHGLRIRARVTHSLSRLA 336 5555566789999********************988754445***********************8555556666667889999999999999999 PP CUB 106 Fkaty 110 Fka+y FUN_000295-T1 337 FKASY 341 99998 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.081 3e+02 3 26 .. 132 157 .. 130 227 .. 0.63 2 ! 9.2 0.0 0.00053 1.9 10 77 .. 625 697 .. 618 709 .. 0.73 3 ! 10.0 0.3 0.00029 1.1 2 79 .. 753 837 .. 752 847 .. 0.67 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.081 fn3_2 3 PkaPvlkvk..nvtqtsvvleWdkle 26 P+aP +v+ + ts+ ++Wd++ FUN_000295-T1 132 PSAPPANVRgsRMSSTSIFVQWDQVP 157 6666554441167899999***9974 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00053 fn3_2 10 vknvtqtsvvleWdklelat...aklksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlktta 77 n+ ts+ ++Wd++ a a l + y+ g r + + ++++++t+l+gL+ t+y++++ +t FUN_000295-T1 625 GYNISSTSIFVQWDHVPAAHqngAMLYYTVTYRAlpsGLRQTVV-VAASAHQTRLTGLNKYTNYSITVFASTCK 697 56999*********997665222667777888853325565544.5678999*************999888875 PP == domain 3 score: 10.0 bits; conditional E-value: 0.00029 fn3_2 2 kPkaPvlkvk.nvtqtsvvleWdklelatak....lksLslykng.qrl.gkipnplkntstKlsgLsvdteyefqlvlkttaGt 79 +P+aP +v+ n t ts+ ++Wd++ + + ++ y+ +r +++ + +t+t l+gL+ +t y++++ +t G+ FUN_000295-T1 753 TPSAPPANVRgNSTSTSIFVQWDQVPPQYQNgvilYYTVTYYRAHyVRFrQRVVVFAPTTQTTLTGLNHNTLYRITVSASTIKGD 837 7999999998699**********99544332111134556677552333123444556788999999999999999999998886 PP >> Glyco_hydro_36C Glycosyl hydrolase family 36 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.028 1e+02 25 55 .. 187 217 .. 179 238 .. 0.82 2 ? 3.6 0.0 0.038 1.4e+02 26 46 .. 670 708 .. 657 742 .. 0.71 3 ! 6.5 0.1 0.0045 16 17 56 .. 799 838 .. 792 842 .. 0.82 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.028 Glyco_hydro_36C 25 pnpalprlrlrGLdpdarYrveeegevysGd 55 + ++ +++ l GL++ a Y+++ + ++ +Gd FUN_000295-T1 187 VAAPTTQTTLTGLNQGALYTISVSASNIRGD 217 567788999************6555555555 PP == domain 2 score: 3.6 bits; conditional E-value: 0.038 Glyco_hydro_36C 26 npalprlrlrGLdpdarYrv..................e 46 ++ +++rl GL++ +Y++ FUN_000295-T1 670 AASAHQTRLTGLNKYTNYSItvfastckdgnvsapifiV 708 5678899************97777776655555555550 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0045 Glyco_hydro_36C 17 fyfqvlarpnpalprlrlrGLdpdarYrveeegevysGde 56 + f+++ + ++ +++ l GL+ + Yr++ + ++ +Gd FUN_000295-T1 799 VRFRQRVVVFAPTTQTTLTGLNHNTLYRITVSASTIKGDG 838 5567777777889999*************88888999985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (864 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 687 (0.0268937); expected 510.9 (0.02) Passed bias filter: 427 (0.0167156); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 8183.09 // Query: FUN_000296-T1 [L=428] Description: FUN_000296 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-26 93.3 14.3 2.4e-14 53.8 4.0 2.4 2 D8C_UMOD Uromodulin-like, D8C domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.9 2.7 5.5e-16 1.4e-11 4 79 .. 128 206 .. 125 214 .. 0.84 2 ! 53.8 4.0 9.3e-19 2.4e-14 9 79 .. 317 384 .. 310 398 .. 0.84 Alignments for each domain: == domain 1 score: 44.9 bits; conditional E-value: 5.5e-16 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm + c sc tn+ wl g hpt+ +g+v r++c +++ n+cc s+ i v+ c g fyvy + p FUN_000296-T1 128 FNGGAGTQMAEKCPKMYSCSTNSSGWLNGTHPTVAEGIVQRKVCflqraSQFFNDCCNH-SKNIGVRNC-GAFYVYRLDPP 206 5568899***********************************99555544677889975.777*****9.89****87554 PP == domain 2 score: 53.8 bits; conditional E-value: 9.3e-19 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 qm dtcv cg+ p wlsgghp++ dg v r++c cc++ s i v+ c gfy+y++ p FUN_000296-T1 317 GTQMADTCVSMRHCGARYPGWLSGGHPSVSDGAVLRKVCFTGNRGCCHY-STFISVRNCN-GFYIYKLS-P 384 57*************************************9999999987.789******7.7****963.3 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (428 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 855 (0.0334703); expected 510.9 (0.02) Passed bias filter: 458 (0.0179291); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 4239.01 // Query: FUN_000297-T1 [L=485] Description: FUN_000297 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-25 88.7 6.3 1.1e-13 51.7 0.9 2.6 2 fn3 Fibronectin type III domain 5.8e-10 39.7 1.2 5.8e-10 39.7 1.2 2.3 2 D8C_UMOD Uromodulin-like, D8C domain 4e-09 37.2 0.2 0.0013 19.6 0.0 2.6 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 3.6e-07 31.2 10.0 0.003 18.6 1.9 2.8 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 0.0002 22.0 1.2 0.49 11.1 0.1 2.7 2 fn3_2 Fibronectin type III domain 0.0006 20.6 0.2 0.0013 19.5 0.2 1.6 1 CUB CUB domain ------ inclusion threshold ------ 0.045 14.5 0.1 0.93 10.3 0.0 2.4 2 Interfer-bind Interferon-alpha/beta receptor, fibronect 0.055 14.0 0.6 9.8 6.7 0.0 2.5 2 NDNF Neuron-derived neurotrophic factor, first 0.13 13.2 0.6 9.1 7.3 0.1 2.7 2 DUF2341 Domain of unknown function (DUF2341) 0.22 11.9 0.3 29 5.1 0.1 2.7 2 GMC_oxred_C_1st GMC oxidoreductase, C-terminal Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.7 0.9 4.3e-17 1.1e-13 2 82 .. 48 137 .. 47 139 .. 0.87 2 ! 39.3 0.5 3.1e-13 7.9e-10 2 75 .. 148 229 .. 147 234 .. 0.87 Alignments for each domain: == domain 1 score: 51.7 bits; conditional E-value: 4.3e-17 fn3 2 aPt.nltvtdvtstsltvsWtpp...dgngpitgYeveyrp..kne....tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 aP n++ + +sts+ v+W++ ++ng i Y+v+yr +++ +v+ + ++++tltgL+ +t+Y+++V a +++G g ++p+ FUN_000297-T1 48 APLaNVSGHNTSSTSIFVQWDQVpaaHQNGAILYYTVTYRAlpSGSvqtnNVTAP-ANQMTLTGLNKYTNYSITVFASTSRGAGNVTAPIF 137 666699999************9999****************65222555677777.899*************************9999986 PP == domain 2 score: 39.3 bits; conditional E-value: 3.1e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp..kne....tvpgsretsvtltgLkpgteYevrVqavngaGeg 75 +P n++ + +sts+ v+W++ ++ng i Y+++ + +++ v + +t+ tltgL++gt Y+++V a + +G g FUN_000297-T1 148 PPANISGYNTSSTSIFVQWNQVpaaHQNGVILYYTITHSSycSGDfstvIVAAP-TTQTTLTGLNQGTLYRISVSASTIKGAG 229 899*****************9999*9**********988876444676566666.9*******************99988876 PP >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 3.3 8.4e+03 29 50 .. 313 334 .. 289 343 .. 0.57 2 ! 39.7 1.2 2.3e-13 5.8e-10 9 73 .. 418 485 .] 411 485 .] 0.84 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 3.3 D8C_UMOD 29 wlsgghptledgvvsrnfcahw 50 l t dg + +c+ FUN_000297-T1 313 HLEIENGTYADGSTTTRMCSNL 334 3444445666666666666655 PP == domain 2 score: 39.7 bits; conditional E-value: 2.3e-13 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyv 73 qm d+c sc tn+ wl g hpt+ +g+v r++c +++ ++cc + + i v+ c g fyv FUN_000297-T1 418 GTQMADACPKMYSCSTNSSGWLNGTHPTVAEGIVKRKVCfsqrvSQFLKDCCNYS-KNISVRNC-GAFYV 485 57***********************************994433335668999985.569***99.78887 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 4.9e-07 0.0013 16 75 .. 75 134 .. 58 148 .. 0.82 2 ! 15.0 0.0 1.3e-05 0.032 17 71 .. 175 229 .. 157 236 .. 0.84 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 4.9e-07 FN3_DSCAM-DSCAML_C 16 ggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaey 75 ++ il+++v yr + + ++ + +++++++++++L+ t Y+++v A + G+ + + FUN_000297-T1 75 QNGAILYYTVTYRALPSGSVQTNNVTAPANQMTLTGLNKYTNYSITVFASTSRGAGNVTA 134 4568*************999999999************************9988877655 PP == domain 2 score: 15.0 bits; conditional E-value: 1.3e-05 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGst 71 + il++++ + + + ++ +v +++++++++++L+++t Y+++v+A G+ FUN_000297-T1 175 NGVILYYTITHSSYCSGDFSTVIVAAPTTQTTLTGLNQGTLYRISVSASTIKGAG 229 5579********************************************9887765 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 1.9 1.2e-06 0.003 9 83 .. 56 126 .. 51 140 .. 0.75 2 ! 16.3 1.3 6.4e-06 0.016 10 82 .. 156 224 .. 149 233 .. 0.74 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 1.2e-06 Pur_ac_phosph_N 9 tg.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 + +sts+ v+W + +++++++++y+ +++al s + +t+ + ++ +++tltgL+ t+Y +v +++s FUN_000297-T1 56 HNtSSTSIFVQWDQVpaAHQNGAILYYTVTYRALPSGSVQTN-------NVTAPANQMTLTGLNKYTNYSITVFASTS 126 5667**********7434668888888888888766544333.......3567899*****************87764 PP == domain 2 score: 16.3 bits; conditional E-value: 6.4e-06 Pur_ac_phosph_N 10 g.pstsmtvsWrtpe.attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +sts+ v+W++ + a+++ v+ y t ++++ + + st+ + +++ tltgL+ gt Y +v +++ FUN_000297-T1 156 NtSSTSIFVQWNQVPaAHQNGVILYYTITHSSYCSG--DFSTV----IVAAPTTQTTLTGLNQGTLYRISVSAST 224 336**********74377777877777776655544..44443....24678999***************98875 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.1 0.1 0.00019 0.49 2 78 .. 45 128 .. 44 135 .. 0.69 2 ! 8.9 0.2 0.00092 2.4 3 89 .] 145 238 .. 143 238 .. 0.72 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00019 fn3_2 2 kPkaPvlkv..knvtqtsvvleWdklelat...aklksLslykngqrlgkipnplk..ntstKlsgLsvdteyefqlvlkttaG 78 +P+aP +v +n+ ts+ ++Wd++ a a l + y+ +n+++ ++++ l+gL+ t+y++++ +t+ G FUN_000297-T1 45 RPSAPLANVsgHNTSSTSIFVQWDQVPAAHqngAILYYTVTYRALPSGSVQTNNVTapANQMTLTGLNKYTNYSITVFASTSRG 128 68888766633799***********9766512245666667776443333333332115678899**********999999977 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00092 fn3_2 3 PkaP..vlkvknvtqtsvvleWdklelataklksLslykngqrlgkip.......nplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 P+aP +++ n+ ts+ ++W+++ +a+ ++ly +++ + ++ +t+t l+gL+ t y++++ +t G +s i ++t FUN_000297-T1 145 PSAPpaNISGYNTSSTSIFVQWNQVP--AAHQNGVILYYTITHSSYCSgdfstviVAAPTTQTTLTGLNQGTLYRISVSASTIKGAGSSFYIGIET 238 666622344469999********875..566667777766665544443333333566788999******************99998888777766 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.2 5.1e-07 0.0013 24 79 .. 278 333 .. 257 356 .. 0.84 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 5.1e-07 CUB 24 nkeCvweirvekgksvklkfedfeleeeee.caydyvevrdgeeasskllgkfcGse 79 +++C w+i ++kg++vkl ++ ++ + c ++e+ +g a+ ++ ++c s+ FUN_000297-T1 278 SQTCSWKIMADKGEQVKLVLKRVKITLCGSsCSCGHLEIENGTYADGSTTTRMC-SN 333 689*******************999865445***************99999999.44 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.00036 0.93 42 84 .. 80 123 .. 57 133 .. 0.88 2 ? 1.4 0.0 0.22 5.6e+02 62 85 .. 200 223 .. 168 231 .. 0.78 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00036 Interfer-bind 42 lqYkvsywknssn.kekkelestnelvvlsdLepnteYCvsVqa 84 l Y+v+y+ s ++++++ + ++++l+ L++ t+Y ++V a FUN_000297-T1 80 LYYTVTYRALPSGsVQTNNVTAPANQMTLTGLNKYTNYSITVFA 123 789****9987766899*********************999987 PP == domain 2 score: 1.4 bits; conditional E-value: 0.22 Interfer-bind 62 stnelvvlsdLepnteYCvsVqae 85 ++++ +l+ L+++t Y +sV+a+ FUN_000297-T1 200 APTTQTTLTGLNQGTLYRISVSAS 223 4567778999*******9999984 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.0038 9.8 87 111 .. 102 126 .. 56 136 .. 0.84 2 ? 5.0 0.1 0.013 34 86 121 .. 200 235 .. 155 238 .. 0.81 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0038 NDNF 87 kktvqtvseLkpdtqYyfdvFavdq 111 +++t+++L++ t+Y ++vFa + FUN_000297-T1 102 PANQMTLTGLNKYTNYSITVFASTS 126 56999****************9765 PP == domain 2 score: 5.0 bits; conditional E-value: 0.013 NDNF 86 gkktvqtvseLkpdtqYyfdvFavdqkrntstaylg 121 +t++t+++L++ t Y+++v a k s++y+g FUN_000297-T1 200 APTTQTTLTGLNQGTLYRISVSASTIKGAGSSFYIG 235 45789999*************999999999999987 PP >> DUF2341 Domain of unknown function (DUF2341) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.068 1.7e+02 25 51 .. 57 83 .. 52 96 .. 0.81 2 ? 7.3 0.1 0.0036 9.1 23 54 .. 154 185 .. 149 199 .. 0.85 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.068 DUF2341 25 ttekaliWvkvpsipangsktiylyyg 51 +t+++ i+v+ +++pa ++ lyy FUN_000297-T1 57 NTSSTSIFVQWDQVPAAHQNGAILYYT 83 788999*********887777777774 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0036 DUF2341 23 dattekaliWvkvpsipangsktiylyygnas 54 ++t+++ i+v+ +++pa ++ + lyy + FUN_000297-T1 154 GYNTSSTSIFVQWNQVPAAHQNGVILYYTITH 185 58999**********************97555 PP >> GMC_oxred_C_1st GMC oxidoreductase, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.011 29 13 61 .. 38 86 .. 31 119 .. 0.88 2 ? 4.0 0.0 0.026 66 23 62 .. 147 186 .. 135 194 .. 0.88 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.011 GMC_oxred_C_1st 13 sdptGtlqstipvlgidnwddpenpvfAeiaplPlgletfaslylaitk 61 s +tG ++ + p ++ + +++++f + +P+ ++ a ly+++t FUN_000297-T1 38 SPTTGPQRPSAPLANVSGHNTSSTSIFVQWDQVPAAHQNGAILYYTVTY 86 567999999************************************9985 PP == domain 2 score: 4.0 bits; conditional E-value: 0.026 GMC_oxred_C_1st 23 ipvlgidnwddpenpvfAeiaplPlgletfaslylaitkn 62 p +i ++ +++++f + +P+ ++ + ly++it+ FUN_000297-T1 147 APPANISGYNTSSTSIFVQWNQVPAAHQNGVILYYTITHS 186 577899999****************************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (485 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 848 (0.0331963); expected 510.9 (0.02) Passed bias filter: 503 (0.0196907); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4786.11 // Query: FUN_000298-T1 [L=231] Description: FUN_000298 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-24 85.2 6.5 1.9e-12 47.7 1.5 2.1 2 fn3 Fibronectin type III domain 2e-06 28.5 0.2 0.0025 18.6 0.0 2.3 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 4.6e-05 24.4 11.4 0.017 16.2 1.7 3.2 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 0.00055 20.5 6.8 0.11 13.2 0.8 3.1 2 fn3_2 Fibronectin type III domain ------ inclusion threshold ------ 0.033 14.9 0.1 9 7.1 0.0 2.3 2 Interfer-bind Interferon-alpha/beta receptor, fibronect 0.058 13.9 2.2 0.93 10.1 0.8 2.7 2 NDNF Neuron-derived neurotrophic factor, first 0.13 12.9 0.5 7.7 7.2 0.0 2.5 2 Fn3_VIN3 VIN3-like, fibronectin type-III domain Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.1 0.2 1.2e-13 4.5e-10 2 82 .. 6 93 .. 5 95 .. 0.82 2 ! 47.7 1.5 5.1e-16 1.9e-12 2 78 .. 104 190 .. 103 195 .. 0.87 Alignments for each domain: == domain 1 score: 40.1 bits; conditional E-value: 1.2e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ +++st++ v+W++ + n + Y+v+y + v + +++ tltgL+ +t+Y+++V a + + g s+p+ FUN_000298-T1 6 PPANVSGYNISSTTIFVQWDQVptaHHNHALLYYTVTYIALPSglqqteIVAAP-AHQTTLTGLNKYTNYSFTVFASTCK-AGNVSAPIF 93 899*****************999999999999********55523444345555.899*****************95544.667777775 PP == domain 2 score: 47.7 bits; conditional E-value: 5.1e-16 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne........tvpgsr.etsvtltgLkpgteYevrVqavngaGegees 78 +P n+t + +sts+ v+W++ +ng i Y+v+yr n v +t+ tltgL++gt Y+++V a +++G+g+ + FUN_000298-T1 104 PPANVTGNSKSSTSIFVQWDQVppsYQNGVILFYTVTYRLYNRyrrflhrvIVA--VpTTQTTLTGLNQGTLYTISVSASTSKGRGPST 190 899****************98778*99*************88888977765333..14788**********************999754 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.1 0.0013 4.7 20 80 .. 36 97 .. 15 105 .. 0.75 2 ! 18.6 0.0 6.7e-07 0.0025 19 75 .. 133 191 .. 114 204 .. 0.83 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0013 FN3_DSCAM-DSCAML_C 20 ilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhn.eaGsteaeyefaTl 80 +l+++v y + ++ +++++++++++L+ t Y+++v A +aG +a + + T FUN_000298-T1 36 LLYYTVTYIALPSGLQQTEIVAAPAHQTTLTGLNKYTNYSFTVFASTcKAGNVSAPIFIVTD 97 6677777777666555555556789999***************9864389998888777775 PP == domain 2 score: 18.6 bits; conditional E-value: 6.7e-07 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsn..nkeqeklviedLkpatwYelkvtAhneaGsteaey 75 il+++v yr ++ + l+ + +++++++++L+++t Y+++v+A + G ++y FUN_000298-T1 133 VILFYTVTYRLYNRYRRFLHRVivAVPTTQTTLTGLNQGTLYTISVSASTSKGRGPSTY 191 6999*******998776665542267899**********************99877665 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 1.7 4.6e-06 0.017 10 82 .. 14 82 .. 7 96 .. 0.72 2 ! 11.4 2.5 0.00015 0.55 9 83 .. 111 183 .. 105 194 .. 0.63 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 4.6e-06 Pur_ac_phosph_N 10 g.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +st++ v+W + ++++ + ++y+ ++ al s ++t + + h+ tltgL+ t+Y ++v +++ FUN_000298-T1 14 NiSSTTIFVQWDQVptAHHNHALLYYTVTYIALPSGLQQTEIV-------AAPAHQTTLTGLNKYTNYSFTVFAST 82 55799999***99743355777777777777777766655554.......4678******************7765 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00015 Pur_ac_phosph_N 9 tg.pstsmtvsWrtpe.attspvvqygtsssa.lsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 ++ +sts+ v+W + + + ++ v+ + t + +++ +++ tltgL+ gt Y +v +++s FUN_000298-T1 111 NSkSSTSIFVQWDQVPpSYQNGVILFYTVTYRlYNRYRRFLH-----RVIVAVPTTQTTLTGLNQGTLYTISVSASTS 183 444689999999887523355544444444331333222222.....2236778999****************99875 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.6 0.00064 2.3 10 80 .. 12 87 .. 4 96 .. 0.61 2 ! 13.2 0.8 2.9e-05 0.11 3 89 .] 101 196 .. 99 196 .. 0.67 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00064 fn3_2 10 vknvtqtsvvleWdklelataklksLslyk........ngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGty 80 n+ t + ++Wd++ a + + ly +g + ++i ++ +++t l+gL+ t+y+f++ +t FUN_000298-T1 12 GYNISSTTIFVQWDQVPTAHHN--HALLYYtvtyialpSGLQQTEIV-AAPAHQTTLTGLNKYTNYSFTVFASTCKAGN 87 56999999******98655433..33333300001111344444444.34567889*************9999874433 PP == domain 2 score: 13.2 bits; conditional E-value: 2.9e-05 fn3_2 3 PkaPvlkvk..nvtqtsvvleWdklelatak...l...ksLslykngqr.lgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 P+aP +v + ts+ ++Wd++ + + l ly +r l ++ ++ +t+t l+gL+ t y++++ +t+ G +s i++ t FUN_000298-T1 101 PSAPPANVTgnSKSSTSIFVQWDQVPPSYQNgviLfytVTYRLYNRYRRfLHRVIVAVPTTQTTLTGLNQGTLYTISVSASTSKGRGPSTYIHIPT 196 66665555411446799999999986443331112111233466555552345667888999***************************9999876 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.0025 9 42 84 .. 37 80 .. 21 91 .. 0.85 2 ? 5.8 0.0 0.0065 24 43 87 .. 140 183 .. 103 191 .. 0.64 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0025 Interfer-bind 42 lqYkvsywknssn.kekkelestnelvvlsdLepnteYCvsVqa 84 l Y+v+y+ s ++++ + + ++ +l+ L++ t+Y ++V a FUN_000298-T1 37 LYYTVTYIALPSGlQQTEIVAAPAHQTTLTGLNKYTNYSFTVFA 80 789****99999978888889999****************9987 PP == domain 2 score: 5.8 bits; conditional E-value: 0.0065 Interfer-bind 43 qYkvsywknssnkekkelestnelvvlsdLepnteYCvsVqaesr 87 +Y+++ + + + + ++++ +l+ L+++t Y +sV+a+ + FUN_000298-T1 140 TYRLYNRYRRFL-HRVIVAVPTTQTTLTGLNQGTLYTISVSASTS 183 455444444433.2233334555668***************9433 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.8 0.00025 0.93 89 118 .. 61 90 .. 22 96 .. 0.86 2 ? 1.7 0.0 0.098 3.6e+02 88 111 .. 160 183 .. 147 194 .. 0.82 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00025 NDNF 89 tvqtvseLkpdtqYyfdvFavdqkrntsta 118 ++t+++L++ t+Y f+vFa k ++ +a FUN_000298-T1 61 HQTTLTGLNKYTNYSFTVFASTCKAGNVSA 90 57899***************9998888776 PP == domain 2 score: 1.7 bits; conditional E-value: 0.098 NDNF 88 ktvqtvseLkpdtqYyfdvFavdq 111 +t++t+++L++ t Y ++v a + FUN_000298-T1 160 TTQTTLTGLNQGTLYTISVSASTS 183 68999**********999977655 PP >> Fn3_VIN3 VIN3-like, fibronectin type-III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.0 0.0021 7.7 46 74 .. 51 79 .. 11 86 .. 0.74 2 ? 3.6 0.1 0.029 1.1e+02 9 74 .. 116 179 .. 111 186 .. 0.62 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0021 Fn3_VIN3 46 eptctllapntrfvisgLePateYvfkvv 74 + t ++ ap ++ +++gL+ t+Y+f v FUN_000298-T1 51 QQTEIVAAPAHQTTLTGLNKYTNYSFTVF 79 6778899*******************996 PP == domain 2 score: 3.6 bits; conditional E-value: 0.029 Fn3_VIN3 9 tsltviLgsedssssssekivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvv 74 ts+ v ++ +s ++ i Y++ +r + ++ p t+ +++gL+ t Y++ v FUN_000298-T1 116 TSIFVQWDQVPPSY-QNGVILFYTVTYRLYNR-YRRFLHRVIVAVPTTQTTLTGLNQGTLYTISVS 179 55555555554443.24455556665555443.223334456778999999*********999885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (231 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 570 (0.0223136); expected 510.9 (0.02) Passed bias filter: 409 (0.016011); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2303.29 // Query: FUN_000299-T1 [L=341] Description: FUN_000299 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-24 85.2 4.2 8.8e-12 45.6 0.3 2.2 2 fn3 Fibronectin type III domain 4.7e-15 56.0 4.4 1e-14 54.9 4.4 1.5 1 D8C_UMOD Uromodulin-like, D8C domain 1.1e-07 32.5 0.2 0.025 15.4 0.0 2.3 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 4.7e-06 27.6 5.2 0.0081 17.2 1.3 3.2 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 0.00054 20.6 0.1 1.4 9.7 0.1 2.6 2 fn3_2 Fibronectin type III domain ------ inclusion threshold ------ 0.047 14.3 0.3 6.8 7.4 0.1 2.5 2 Fn3_VIN3 VIN3-like, fibronectin type-III domain Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.6 0.3 2.1e-15 8.8e-12 2 82 .. 140 228 .. 139 230 .. 0.89 2 ! 41.0 0.4 5.6e-14 2.4e-10 3 78 .. 240 321 .. 236 327 .. 0.91 Alignments for each domain: == domain 1 score: 45.6 bits; conditional E-value: 2.1e-15 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ +ng + Y+v+yr + v + +++ tltgL+ +t+Y+++V a + +G g s+p FUN_000299-T1 140 PPMNVSGYNTSSTSIFVHWDQVpdaYQNGALLYYTVTYRSLPSgfrqtvVVAAP-AHQTTLTGLNKYTNYSITVFASTCKGAGNVSAPFF 228 899*****************9999999*************55556775555555.899*************************9999975 PP == domain 2 score: 41.0 bits; conditional E-value: 5.6e-14 fn3 3 PtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne....tvpgsretsvtltgLkpgteYevrVqavngaGegees 78 P n++ +++sts+ v+W++ ++ng i Y+++yrp + +v + +t+ tltgL+++t Y ++V a + +G g+ FUN_000299-T1 240 PVNVRGNTISSTSIFVQWDEVpaaRQNGVILYYTITYRPYTVfclvNVFAP-KTQITLTGLNESTIYWISVSASTIKGHGPAR 321 7799999************9999*99*************877899999999.89*********************99999754 PP >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.9 4.4 2.4e-18 1e-14 10 87 .. 44 122 .. 38 123 .. 0.87 Alignments for each domain: == domain 1 score: 54.9 bits; conditional E-value: 2.4e-18 D8C_UMOD 10 vqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyef..vrpt.tcnlayc 87 qm dtcv + cg+ p wlsgghp++ dg v r++c cc++ s i v+ c ggf+vy++ v+p c + yc FUN_000299-T1 44 TQMADTCVKQRHCGASYPGWLSGGHPSVSDGAVLRKVCFTGYWGCCHY-STFISVRNC-GGFFVYKLspVHPYyYCHFRYC 122 79************************************9999999998.778*****9.89****9744666425777777 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 5.8e-06 0.025 4 77 .. 152 227 .. 149 235 .. 0.78 2 ! 15.1 0.0 7.6e-06 0.032 18 73 .. 267 320 .. 248 331 .. 0.80 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 5.8e-06 FN3_DSCAM-DSCAML_C 4 tsvtlnLsaWkd..ggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyef 77 ts+ ++ ++ +d ++ +l+++v yr+ + ++v +++++++++++L+ t Y+++v A G+ + + f FUN_000299-T1 152 TSIFVHWDQVPDayQNGALLYYTVTYRSLPSGFRQTVVVAAPAHQTTLTGLNKYTNYSITVFASTCKGAGNVSAPF 227 55555555555422356799*********9999999999999*********************9888777666555 PP == domain 2 score: 15.1 bits; conditional E-value: 7.6e-06 FN3_DSCAM-DSCAML_C 18 CpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGstea 73 il++++ yr+ + + lv+ ++++++++++L+++t Y ++v+A G+ a FUN_000299-T1 267 GVILYYTITYRPYT--VFCLVNVFAPKTQITLTGLNESTIYWISVSASTIKGHGPA 320 5799*******975..6888888999*********************999887654 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 1.3 1.9e-06 0.0081 10 89 .. 148 227 .. 141 231 .. 0.75 2 ! 9.6 0.1 0.00047 2 10 82 .. 247 313 .. 240 324 .. 0.64 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.9e-06 Pur_ac_phosph_N 10 g.pstsmtvsWrtp.e.attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevy 89 + +sts+ v W + + ++++ ++y+ ++++l s + +t++++ + h+ tltgL+ t+Y +v +++ + s+ + FUN_000299-T1 148 NtSSTSIFVHWDQVpDaYQNGALLYYTVTYRSLPSGFRQTVVVA-------APAHQTTLTGLNKYTNYSITVFASTCkgagNVSAPF 227 3369********97333558889999999999999999888764.......568******************665433334466655 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00047 Pur_ac_phosph_N 10 g.pstsmtvsWrtpe.at.tspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +sts+ v+W + a ++ +++y+ +++ ++ + + ++ tltgL+ +t Y +v +++ FUN_000299-T1 247 TiSSTSIFVQWDEVPaARqNGVILYYTITYRPYTVFCLVN---------VFAPKTQITLTGLNESTIYWISVSAST 313 4457888888888642331333445555555544433322.........345678999**********99998765 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.1 0.00032 1.4 3 78 .. 137 219 .. 135 225 .. 0.71 2 ! 8.3 0.0 0.00086 3.7 8 89 .] 243 327 .. 235 327 .. 0.80 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00032 fn3_2 3 PkaPvlkvk..nvtqtsvvleWdklela...taklksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaG 78 P+aP ++v+ n+ ts+ ++Wd++ a a l + y++ g r + + ++ +++t l+gL+ t+y++++ +t G FUN_000299-T1 137 PSAPPMNVSgyNTSSTSIFVHWDQVPDAyqnGALLYYTVTYRSlpsGFRQTVVV-AAPAHQTTLTGLNKYTNYSITVFASTCKG 219 88888877544999**********964311145566667788533255554444.5667788999***9999999999999877 PP == domain 2 score: 8.3 bits; conditional E-value: 0.00086 fn3_2 8 lkvknvtqtsvvleWdklelatak...lksLslykngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 ++ + + ts+ ++Wd++ a + l + y+ + + ++ + +t++ l+gL+ t y +++ +t G+ ++ +i++ t FUN_000299-T1 243 VRGNTISSTSIFVQWDEVPAARQNgviLYYTITYRPYTVFCLVNVFAPKTQITLTGLNESTIYWISVSASTIKGHGPARHISIAT 327 45567889********998776553324455668888888888888899999***************999999999888888876 PP >> Fn3_VIN3 VIN3-like, fibronectin type-III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.013 55 46 74 .. 185 213 .. 148 220 .. 0.77 2 ? 7.4 0.1 0.0016 6.8 5 73 .. 247 309 .. 243 317 .. 0.67 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.013 Fn3_VIN3 46 eptctllapntrfvisgLePateYvfkvv 74 + t ++ ap ++ +++gL+ t+Y++ v FUN_000299-T1 185 RQTVVVAAPAHQTTLTGLNKYTNYSITVF 213 5678999*****************99886 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0016 Fn3_VIN3 5 dvkatsltviLgsedsssssse.kivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkv 73 +++ts+ v + ++ + ++ i Y++ + y+ ++ap+t+++++gL+ +t Y + v FUN_000299-T1 247 TISSTSIFVQWD--EVPAARQNgVILYYTITY-----RPYTVFCLVNVFAPKTQITLTGLNESTIYWISV 309 566777777553..333333330333333333.....46777788899*****************99877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (341 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 448 (0.0175377); expected 510.9 (0.02) Passed bias filter: 313 (0.0122529); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 3473.33 // Query: FUN_000300-T1 [L=459] Description: FUN_000300 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-27 93.9 19.4 3.5e-14 53.2 3.4 3.3 3 D8C_UMOD Uromodulin-like, D8C domain 0.00035 21.4 0.4 0.0011 19.8 0.2 1.9 2 CUB CUB domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.2 0.059 7.5e+02 33 55 .. 75 97 .. 55 118 .. 0.64 2 ! 48.5 3.0 8.3e-17 1.1e-12 4 79 .. 171 249 .. 168 257 .. 0.84 3 ! 53.2 3.4 2.8e-18 3.5e-14 9 87 .. 306 388 .. 299 389 .. 0.82 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.059 D8C_UMOD 33 ghptledgvvsrnfcahwsnncc 55 t+ dg + +c+h n FUN_000300-T1 75 QDGTFADGFTTTRICSHLLGNTI 97 23455566666677777655544 PP == domain 2 score: 48.5 bits; conditional E-value: 8.3e-17 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm dtc sc tn+ wl g hpt+ +g+v r++c +++ n+cc s+ i v+ c g fyvy + p FUN_000300-T1 171 FSGGAGAQMVDTCPRMYSCSTNSSGWLNGSHPTVAEGIVQRKVCfsqrvSQFLNDCCNH-SKNISVRNC-GAFYVYRLDPP 249 6678999***********************************99544434577999975.777*****9.89****87554 PP == domain 3 score: 53.2 bits; conditional E-value: 2.8e-18 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcah.wsnnccyfqsnpiqvkacpggfyvye...fvrptt..cnlayc 87 qm dtcv cg+ p wlsgghp++ dg v r++c + ccy s i v+ c fyvy+ f rp + c + yc FUN_000300-T1 306 GTQMADTCVKWRHCGALYPGWLSGGHPSVSDGAVLRKVCFTeYRGSCCY-SSTFISVRNCN-EFYVYKlspFYRPHSynCPFRYC 388 57*************************************7516666665.7999******7.6****755578997522556677 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.2 8.6e-08 0.0011 6 84 .. 20 97 .. 12 124 .. 0.77 2 ? -1.7 0.0 0.41 5.2e+03 72 86 .. 252 266 .. 237 277 .. 0.79 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 8.6e-08 CUB 6 tessgsisspnypkeYeenkeCvweirvekgksvklkfedfeleeeee.caydyvevrdgeeasskllgkfcGsekpedi 84 ++++g+i ++y Y+ n++C w+i ++k+++vkl +e++ + c ++ ++dg a+ + ++c + ++i FUN_000300-T1 20 NARNGKIIFSSYY--YRYNQTCSWKIVANKREQVKLVLESIHFRWCGLsCSCGHLVIQDGTFADGFTTTRICSHLLGNTI 97 5566666666665..8889********************9888854435999********99999999999976666655 PP == domain 2 score: -1.7 bits; conditional E-value: 0.41 CUB 72 lgkfcGsekpediks 86 + ++cG++ p+ + FUN_000300-T1 252 YSRYCGNGLPQASEC 266 6799**999987655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (459 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 780 (0.0305344); expected 510.9 (0.02) Passed bias filter: 422 (0.0165199); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4532.72 // Query: FUN_000301-T1 [L=243] Description: FUN_000301 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-27 95.2 6.4 3.9e-14 53.1 0.2 2.2 2 fn3 Fibronectin type III domain 5e-08 33.7 0.1 0.0069 17.2 0.0 2.2 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 3e-07 31.4 7.3 0.0013 19.8 0.4 2.5 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 2.2e-06 28.2 1.9 0.095 13.4 0.0 3.0 2 fn3_2 Fibronectin type III domain ------ inclusion threshold ------ 0.2 12.2 0.2 2.5 8.7 0.0 2.2 2 NDNF Neuron-derived neurotrophic factor, first 0.33 11.4 1.0 7.5 7.1 0.0 2.4 3 DUF4426 Domain of unknown function (DUF4426) 3.4 8.7 7.0 1.1 10.3 2.0 2.6 3 Cadherin-like Cadherin-like beta sandwich domain Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.1 0.2 1.1e-17 3.9e-14 2 82 .. 41 129 .. 40 131 .. 0.88 2 ! 44.5 1.7 5.2e-15 1.9e-11 2 81 .. 140 228 .. 139 231 .. 0.84 Alignments for each domain: == domain 1 score: 53.1 bits; conditional E-value: 1.1e-17 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ ++ng i Y+v yr + v+ +++ tltgL+ +t+Y+++V a +++G g s+p+ FUN_000301-T1 41 PPGNVSGHNTSSTSIFVHWDHIpaaHQNGAILYYTVSYRALPSgfrqtvIVSAR-ANQTTLTGLNKYTNYSISVFASTSKGAGGVSAPIF 129 89******************9889****************55556774444444.999*****************************997 PP == domain 2 score: 44.5 bits; conditional E-value: 5.2e-15 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne.......tvpgsretsvtltgLkpgteYevrVqavngaGegeesepl 81 +P ++ +v+sts+ v+W++ +ng i Y+v+y+ + v + +t+vtltgL+++t Y++++ a +++G g+ + + FUN_000301-T1 140 PPAYFRGNRVSSTSIFVQWDQVppqYQNGVILYYTVTYYRVHYsrfpqtvFVAAP-TTQVTLTGLNQDTLYSISLSASTRKGGGPSTSIS 228 788889999**********98778*99************9555655654566666.9************************999765544 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 1.9e-06 0.0069 16 71 .. 67 122 .. 50 139 .. 0.80 2 ! 14.6 0.0 1.3e-05 0.046 19 69 .. 169 220 .. 149 235 .. 0.79 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.9e-06 FN3_DSCAM-DSCAML_C 16 ggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGst 71 ++ il+++v+yr + ++v ++ ++++++++L+ t Y+++v A + G+ FUN_000301-T1 67 QNGAILYYTVSYRALPSGFRQTVIVSARANQTTLTGLNKYTNYSISVFASTSKGAG 122 4568**********998888888778889999*****************9998864 PP == domain 2 score: 14.6 bits; conditional E-value: 1.3e-05 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewil.vsnnkeqeklviedLkpatwYelkvtAhneaG 69 il+++v y + + +++ + v +++++++++++L++ t Y+++++A G FUN_000301-T1 169 VILYYTVTYYRVHYSRFPQtVFVAAPTTQVTLTGLNQDTLYSISLSASTRKG 220 6999***99888888776615678999********************98876 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.4 3.6e-07 0.0013 9 84 .. 48 123 .. 42 132 .. 0.80 2 ! 14.5 1.6 1.6e-05 0.059 11 83 .. 150 218 .. 144 231 .. 0.70 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 3.6e-07 Pur_ac_phosph_N 9 tg.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....g 84 + +sts+ v W +++++++++y+ s++al s + +t+ + s+ ++ tltgL+ t+Y +v +++s g FUN_000301-T1 48 HNtSSTSIFVHWDHIpaAHQNGAILYYTVSYRALPSGFRQTVIV-------SARANQTTLTGLNKYTNYSISVFASTSkgagG 123 5667*********9643477999***********9999988764.......6889******************8886544444 PP == domain 2 score: 14.5 bits; conditional E-value: 1.6e-05 Pur_ac_phosph_N 11 pstsmtvsWrtpe.attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 +sts+ v+W + + + ++ v+ y t + + + +++ + ++++tltgL+ +t Y + ++++ FUN_000301-T1 150 SSTSIFVQWDQVPpQYQNGVILYYTVTYYRVHYSRFPQTV-----FVAAPTTQVTLTGLNQDTLYSISLSASTR 218 5899999999976255777777777775543332222222.....356889***************99887764 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 2.6e-05 0.095 3 78 .. 38 120 .. 36 130 .. 0.75 2 ! 12.7 0.5 4.3e-05 0.16 8 89 .] 144 231 .. 135 231 .. 0.67 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 2.6e-05 fn3_2 3 PkaP..vlkvknvtqtsvvleWdklelat...aklksLslyk...ngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaG 78 P+aP +++ +n+ ts+ ++Wd++ a a l + y+ +g r + i ++ ++++t l+gL+ t+y++++ +t+ G FUN_000301-T1 38 PSAPpgNVSGHNTSSTSIFVHWDHIPAAHqngAILYYTVSYRalpSGFRQTVIVSA-RANQTTLTGLNKYTNYSISVFASTSKG 120 666633466689************98765222445555667733357888888765.666888***************999988 PP == domain 2 score: 12.7 bits; conditional E-value: 4.3e-05 fn3_2 8 lkvknvtqtsvvleWdkl..elataklk..sLslykngqrlgkip....nplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 ++ + v ts+ ++Wd++ + ++ + ++ y+ + p ++ +t++ l+gL+ dt y+++l +t G +s +i++ t FUN_000301-T1 144 FRGNRVSSTSIFVQWDQVppQYQNGVILyyTVTYYRVH--YSRFPqtvfVAAPTTQVTLTGLNQDTLYSISLSASTRKGGGPSTSISIVT 231 45567899999999999833333333331134445533..333331122566788999*********************99999999866 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.0 0.00068 2.5 85 111 .. 92 118 .. 44 125 .. 0.81 2 ? 1.2 0.1 0.14 4.9e+02 88 106 .. 195 213 .. 170 226 .. 0.86 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00068 NDNF 85 vgkktvqtvseLkpdtqYyfdvFavdq 111 + +++t+++L++ t+Y ++vFa + FUN_000301-T1 92 SARANQTTLTGLNKYTNYSISVFASTS 118 456789999**************9765 PP == domain 2 score: 1.2 bits; conditional E-value: 0.14 NDNF 88 ktvqtvseLkpdtqYyfdv 106 +t+ t+++L++dt Y +++ FUN_000301-T1 195 TTQVTLTGLNQDTLYSISL 213 68999**********8776 PP >> DUF4426 Domain of unknown function (DUF4426) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 4.7 1.7e+04 37 59 .. 24 47 .. 21 51 .. 0.51 2 ? 2.6 0.1 0.048 1.7e+02 7 55 .. 74 126 .. 70 134 .. 0.71 3 ? 7.1 0.0 0.0021 7.5 6 53 .. 177 225 .. 173 236 .. 0.82 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 4.7 DUF4426 37 lvnisvlkksekgke.aveaevsg 59 +++ +v +++ + + a + +vsg FUN_000301-T1 24 ILTTTVSSTTGPQRPsAPPGNVSG 47 444455555554444455555555 PP == domain 2 score: 2.6 bits; conditional E-value: 0.048 DUF4426 7 yevhYsalnstfLtpev....AkaygleRskykglvnisvlkksekgkeavea 55 y+v Y al+s f + + A+++ l+ ++ isv +++kg +v+a FUN_000301-T1 74 YTVSYRALPSGFRQTVIvsarANQTTLTGLNKYTNYSISVFASTSKGAGGVSA 126 899*****997755544332266667777666667778888877777777766 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0021 DUF4426 6 dyevhYsalnstfLtpevAkaygleRskykglvnisvlkksekgke.av 53 y+vhYs ++ t+ ++ +++ l+ ++ l is+ ++ kg ++ FUN_000301-T1 177 YYRVHYSRFPQTVFVAAPTTQVTLTGLNQDTLYSISLSASTRKGGGpST 225 69**********************************9998888765333 PP >> Cadherin-like Cadherin-like beta sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 2.4 8.6e+03 39 47 .. 26 34 .. 15 60 .. 0.49 2 ? -0.5 0.1 0.69 2.5e+03 30 37 .. 90 104 .. 63 132 .. 0.60 3 ? 10.3 2.0 0.00029 1.1 17 65 .. 186 234 .. 172 238 .. 0.89 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 2.4 Cadherin-like 39 gatvtvngv 47 ++tv+ + FUN_000301-T1 26 TTTVSSTTG 34 233333333 PP == domain 2 score: -0.5 bits; conditional E-value: 0.69 Cadherin-like 30 tvtataa.......n 37 v+a a+ n FUN_000301-T1 90 IVSARANqttltglN 104 333333332223332 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00029 Cadherin-like 17 eYtatVdydvtsvtvtataansgatvtvngvavdsgtesadvnLneGrn 65 t+ V+ ++t+vt+t +++ +++++ ++ ++g+ s+++++ G+n FUN_000301-T1 186 PQTVFVAAPTTQVTLTGLNQDTLYSISLSASTRKGGGPSTSISIVTGNN 234 4689******************************999999999977977 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (243 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 593 (0.0232139); expected 510.9 (0.02) Passed bias filter: 428 (0.0167547); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2418.39 // Query: FUN_000302-T1 [L=237] Description: FUN_000302 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-12 46.4 2.7 4.6e-12 46.4 2.7 2.1 2 D8C_UMOD Uromodulin-like, D8C domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.025 6.4e+02 8 59 .. 6 59 .. 2 87 .. 0.66 2 ! 46.4 2.7 1.8e-16 4.6e-12 4 76 .. 132 207 .. 129 218 .. 0.81 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.025 D8C_UMOD 8 qsvqmpdtcvdenscgtnapl.wlsgghptledgvvsrnfcahwsnnc.cyfqs 59 + v++ v+ cg + + l t dg + +c+ n+ y q FUN_000302-T1 6 EQVKLVLKSVELYYCGISCSFgHLEIQNGTYADGSTTTRMCSSLLGNVtIYSQV 59 566666667777778877665357777889999999999998876555145553 PP == domain 2 score: 46.4 bits; conditional E-value: 1.8e-16 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyef 76 f g qm ++c sc tn+ wlsg hpt+ +g+v r++c +++ +cc +s+ i v+ c g fyvy + FUN_000302-T1 132 FSGGAGTQMAEACPKMYSCSTNSSGWLSGTHPTVAEGIVQRKVCfsqrvSQFFYDCCN-HSKNISVRNC-GAFYVYRL 207 6678999***********************************9943332345567886.5778*****9.89****85 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (237 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 660 (0.0258368); expected 510.9 (0.02) Passed bias filter: 429 (0.0167939); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.45 # Mc/sec: 2139.12 // Query: FUN_000303-T1 [L=190] Description: FUN_000303 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-13 51.1 5.7 3.1e-13 50.2 5.7 1.5 1 D8C_UMOD Uromodulin-like, D8C domain 1.3e-09 38.6 0.2 2.2e-09 37.9 0.2 1.4 1 fn3 Fibronectin type III domain ------ inclusion threshold ------ 0.016 16.3 0.7 0.033 15.3 0.7 1.6 1 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 0.055 14.3 0.0 0.094 13.6 0.0 1.5 1 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.2 5.7 4.8e-17 3.1e-13 12 87 .. 1 77 [. 1 78 [. 0.89 Alignments for each domain: == domain 1 score: 50.2 bits; conditional E-value: 4.8e-17 D8C_UMOD 12 mpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyefv...rpttcnlayc 87 m d+cv cg+ p wlsgghp++ dg v r++c cc + s i v+ c gfyvy++ +cn+ yc FUN_000303-T1 1 MADSCVSMRHCGARYPGWLSGGHPSVSDGAVLRKVCFTGYRGCCQY-STFISVRNCS-GFYVYKLSpvySYYSCNFRYC 77 89******************************************98.778******6.7****9851114568*****9 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 0.2 3.5e-13 2.2e-09 2 80 .. 95 180 .. 94 184 .. 0.78 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 3.5e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeesep 80 +P n++ +++st + v+W++ ++n + Y+v+yr + v + +++ tltgL+ +t+Y+++V a + + g s p FUN_000303-T1 95 SPANVSGYNISSTRIFVQWDQVpapHQNIALLYYTVTYRALPSgfrqtvLVAAP-AHQTTLTGLNKYTNYSITVFASTCK-AGNVSVP 180 799*****************999666666666********55556774444444.899*****************95543.5555555 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.7 5.1e-06 0.033 10 82 .. 103 171 .. 95 185 .. 0.77 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 5.1e-06 Pur_ac_phosph_N 10 g.pstsmtvsWrtpe..attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +st + v+W + + +++ + ++y+ +++al s + +t+ + + h+ tltgL+ t+Y +v +++ FUN_000303-T1 103 NiSSTRIFVQWDQVPapHQNIALLYYTVTYRALPSGFRQTVLV-------AAPAHQTTLTGLNKYTNYSITVFAST 171 557999999**99852244666778888888888888777665.......5678*****************97765 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 1.5e-05 0.094 19 72 .. 124 178 .. 104 189 .. 0.82 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.5e-05 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhn.eaGste 72 +l+++v yr + ++v +++++++++++L+ t Y+++v A +aG + FUN_000303-T1 124 ALLYYTVTYRALPSGFRQTVLVAAPAHQTTLTGLNKYTNYSITVFASTcKAGNVS 178 689********999998999899999******************98642777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (190 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 598 (0.0234097); expected 510.9 (0.02) Passed bias filter: 360 (0.0140928); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.81s 00:00:01.12 Elapsed: 00:00:00.51 # Mc/sec: 1519.17 // Query: FUN_000304-T1 [L=501] Description: FUN_000304 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-23 83.1 20.4 6.5e-15 55.6 4.5 3.0 3 D8C_UMOD Uromodulin-like, D8C domain 2.5e-08 34.5 3.1 5.9e-08 33.3 3.1 1.6 1 fn3 Fibronectin type III domain 3.1e-06 28.0 0.9 7e-06 26.8 0.9 1.6 1 CUB CUB domain ------ inclusion threshold ------ 0.011 16.6 1.6 0.018 15.9 0.2 2.0 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.14 12.8 0.7 0.3 11.7 0.2 1.7 2 Fn3_VIN3 VIN3-like, fibronectin type-III domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.2 0.94 4.8e+03 33 66 .. 165 200 .. 143 217 .. 0.64 2 ! 37.0 2.9 8e-13 4.1e-09 4 79 .. 263 342 .. 260 349 .. 0.82 3 ! 55.6 4.5 1.3e-18 6.5e-15 10 87 .. 400 478 .. 392 479 .. 0.87 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.94 D8C_UMOD 33 ghptledgvvsrnfcahwsnnccyfq..snpiqvka 66 t dg + +c++ n+ + s ++++a FUN_000304-T1 165 QNGTYADGSTTSRMCSYLLGNVTIYShvSHGLKIQA 200 455777888877888877666544321244555555 PP == domain 2 score: 37.0 bits; conditional E-value: 8e-13 D8C_UMOD 4 fingqsvqmpdtcvde.nscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm + c sc tn+ wl g hpt+ +g+v r++c +++ n+cc s+ i v+ c g f+vy + p FUN_000304-T1 263 FSGGPGTQMAEVCPKRmYSCSTNSSGWLNGTHPTVAEGIVKRKVCfsqrvSQFFNDCCNH-SKNIGVRNC-GAFHVYRLDPP 342 5678889******87537*************************99544434577999975.777*****9.89****87655 PP == domain 3 score: 55.6 bits; conditional E-value: 1.3e-18 D8C_UMOD 10 vqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyefv..rp.ttcnlayc 87 qm d cv + cg+ p wlsgghp+l dg v r++c cc++ s i v+ c gfyvy++ +p cn+ yc FUN_000304-T1 400 NQMADNCVKQRHCGARYPGWLSGGHPSLSDGAVLRKVCFTRYWGCCHY-STFISVRNCS-GFYVYKLSpaHPyYYCNFRYC 478 69************************************999999**98.779******6.7****9862244246999999 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 3.1 1.1e-11 5.9e-08 2 78 .. 6 90 .. 5 96 .. 0.84 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 1.1e-11 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne.tvpgsr.....etsvtltgLkpgteYevrVqavngaGegees 78 +P n++ + tsts+ v+W++ +ng i Y+v y+ ++ + p++ + + tlt L+++t Y+++V a +++G+g+ + FUN_000304-T1 6 SPANVRG-NSTSTSIFVQWEQVpssYQNGVILYYTVIYHRAHYnRFPQTVivfapTIQTTLTSLNQSTVYSISVSASTSKGDGPAT 90 6888888.9***********9999*99***********99666644444445544667************************9865 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.9 1.4e-09 7e-06 9 77 .. 109 180 .. 98 196 .. 0.81 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 1.4e-09 CUB 9 sgsisspnypkeYee.nkeCvweirvekgksvklkfedfeleeeee..caydyvevrdgeeasskllgkfcG 77 +g+i + y Y++ n++C w+i ++kg++vkl +e + +++ c d++e+++g a+ ++ ++c FUN_000304-T1 109 NGEIIFYGYYYYYNRyNQTCSWKILANKGEQVKLVIEYMYVNTWCGwsCSCDHLEIQNGTYADGSTTSRMCS 180 5556556666666543899*******************9999766577***************999999994 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 0.2 3.5e-06 0.018 19 80 .. 34 96 .. 14 101 .. 0.83 2 ? -1.9 0.1 1.3 6.4e+03 28 57 .. 123 152 .. 116 156 .. 0.78 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 3.5e-06 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvs.nnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTl 80 il+++v y++++ +++ + +++ +++++ L+++t Y+++v+A + G a+y T+ FUN_000304-T1 34 VILYYTVIYHRAHYNRFPQTViVFAPTIQTTLTSLNQSTVYSISVSASTSKGDGPATYIYITT 96 6999**9999999998877651558999*************************9999987775 PP == domain 2 score: -1.9 bits; conditional E-value: 1.3 FN3_DSCAM-DSCAML_C 28 rkkgeeewilvsnnkeqeklviedLkpatw 57 r +++ +w + n+ eq klvie + tw FUN_000304-T1 123 RYNQTCSWKILANKGEQVKLVIEYMYVNTW 152 344556899999999999999998888877 PP >> Fn3_VIN3 VIN3-like, fibronectin type-III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.2 5.8e-05 0.3 8 79 .. 14 84 .. 11 92 .. 0.78 2 ? -3.9 0.0 4.5 2.3e+04 57 70 .. 458 471 .. 451 473 .. 0.79 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 5.8e-05 Fn3_VIN3 8 atsltviLgsedssssss.ekivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvvsfnet 79 +ts + ++ e++ ss + i Y++ + +a+ +++p+ t +++ap + ++++L+ +t Y++ v + +++ FUN_000304-T1 14 STSTSIFVQWEQVPSSYQnGVILYYTVIYHRAHYNRFPQ--TVIVFAPTIQTTLTSLNQSTVYSISVSASTSK 84 566666667777655555056788999999999888886..66899******************998766555 PP == domain 2 score: -3.9 bits; conditional E-value: 4.5 Fn3_VIN3 57 rfvisgLePateYv 70 f++ +L+Pa Y+ FUN_000304-T1 458 GFYVYKLSPAHPYY 471 57899999998886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (501 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 418 (0.0163633); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 4781.37 // Query: FUN_000305-T1 [L=274] Description: FUN_000305 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-22 80.2 9.8 4.5e-11 43.3 1.1 2.2 2 fn3 Fibronectin type III domain 1.3e-09 38.8 0.3 0.0025 18.6 0.0 2.4 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.00048 20.7 3.7 0.17 12.5 0.3 2.8 2 fn3_2 Fibronectin type III domain 0.0019 19.3 12.1 0.31 12.2 2.4 2.9 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.3 1.1 7e-15 4.5e-11 2 82 .. 45 128 .. 44 130 .. 0.91 2 ! 41.6 2.0 2.4e-14 1.5e-10 2 78 .. 139 224 .. 138 230 .. 0.87 Alignments for each domain: == domain 1 score: 43.3 bits; conditional E-value: 7e-15 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ + i Y+v yr + +v+ + +++ +ltgL+ +t+Y++ V a + +G g s+p+ FUN_000305-T1 45 PPANVSGYNTSSTSVFVQWDQV--PAAILYYTVSYRALPSgpvqtkNVTAP-ANQTNLTGLNKYTNYSILVFASTWKGAGNISAPIF 128 899*******************..*************44445666788888.899*****************************997 PP == domain 2 score: 41.6 bits; conditional E-value: 2.4e-14 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp.kne.......tvpgsretsvtltgLkpgteYevrVqavngaGegees 78 +P n+t + +sts+ v+W++ +ng i Y+v+yr + v + +++ tltgL+++t Y++ V a +++G g+++ FUN_000305-T1 139 SPANVTGNSTSSTSILVKWDQVplpYQNGVILYYTVTYRLyY-NglfpqtvVVAAP-TNQTTLTGLNQSTLYSIAVSASTSKGGGPFT 224 799****9999*********999**99*************63.3366664555555.899************************9986 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.0 4e-07 0.0025 10 72 .. 60 122 .. 52 136 .. 0.84 2 ! 18.2 0.0 5.4e-07 0.0035 16 71 .. 165 221 .. 145 234 .. 0.75 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 4e-07 FN3_DSCAM-DSCAML_C 10 LsaWkdggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGste 72 + +W++ il+++v+yr + ++ + +++++++ +++L+ t Y++ v A G+ + FUN_000305-T1 60 FVQWDQVPAAILYYTVSYRALPSGPVQTKNVTAPANQTNLTGLNKYTNYSILVFASTWKGAGN 122 56899999**************999999999999********************988766544 PP == domain 2 score: 18.2 bits; conditional E-value: 5.4e-07 FN3_DSCAM-DSCAML_C 16 ggCpilsfvveyrkkgeeewilv.snnkeqeklviedLkpatwYelkvtAhneaGst 71 ++ il+++v yr + + + +++++++++++L+++t Y++ v+A + G FUN_000305-T1 165 QNGVILYYTVTYRLYYNGLFPQTvVVAAPTNQTTLTGLNQSTLYSIAVSASTSKGGG 221 45579*********99998876515678999*******************9988855 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.2 0.00057 3.6 8 76 .. 49 117 .. 40 130 .. 0.64 2 ! 12.5 0.3 2.7e-05 0.17 11 87 .. 146 228 .. 134 230 .. 0.75 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00057 fn3_2 8 lkvknvtqtsvvleWdklelataklksLslykn....gqrlgkipnplkntstKlsgLsvdteyefqlvlktt 76 ++ n+ tsv ++Wd++ +a l + y+ +++ +++ p +++t l+gL+ t+y++ + +t FUN_000305-T1 49 VSGYNTSSTSVFVQWDQVP--AAILYYTVSYRAlpsgPVQTKNVTAP--ANQTNLTGLNKYTNYSILVFASTW 117 3446999*********875..45555555565411113444555544..456789999999999987777765 PP == domain 2 score: 12.5 bits; conditional E-value: 2.7e-05 fn3_2 11 knvtqtsvvleWdklelatak......lksLslykngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikv 87 +++ ts+ ++Wd++ l + ly ng +++ ++ +++t l+gL+ t y++ + +t+ G + i+v FUN_000305-T1 146 NSTSSTSILVKWDQVPLPYQNgvilyyTVTYRLYYNGLFPQTVVVAAPTNQTTLTGLNQSTLYSIAVSASTSKGGGPFTYIHV 228 455689*********99765522211123557999**99999999999999********************998655555555 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.1 2.3 0.0001 0.64 10 82 .. 53 116 .. 46 127 .. 0.66 2 ! 12.2 2.4 4.8e-05 0.31 5 83 .. 144 217 .. 140 230 .. 0.72 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.0001 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +sts+ v+W + +a ++++y+ s++al s +t ++ ++ +ltgL+ t+Y v +++ FUN_000305-T1 53 NtSSTSVFVQWDQVPA---AILYYTVSYRALPSGPVQTK-N------VTAPANQTNLTGLNKYTNYSILVFAST 116 3369*********875...55555555555544322222.1......244567888999999999988776665 PP == domain 2 score: 12.2 bits; conditional E-value: 4.8e-05 Pur_ac_phosph_N 5 hlsltgpstsmtvsWrtpe.attspvvqygtsssa..lsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 + + t+ sts+ v W + + + ++ v+ y t + ++ +++t+++ + +++ tltgL+ +t Y v +++s FUN_000305-T1 144 TGNSTS-STSILVKWDQVPlPYQNGVILYYTVTYRlyYNGLFPQTVVV-------AAPTNQTTLTGLNQSTLYSIAVSASTS 217 444455.9*********8744477777777776553345556655554.......46789*****************99874 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (274 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 673 (0.0263457); expected 510.9 (0.02) Passed bias filter: 438 (0.0171462); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2744.75 // Query: FUN_000306-T1 [L=101] Description: FUN_000306 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 784 (0.0306909); expected 510.9 (0.02) Passed bias filter: 438 (0.0171462); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1038.20 // Query: FUN_000307-T1 [L=167] Description: FUN_000307 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 661 (0.0258759); expected 510.9 (0.02) Passed bias filter: 594 (0.0232531); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1626.81 // Query: FUN_000310-T1 [L=198] Description: FUN_000310 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-06 27.1 0.1 2.3e-05 25.5 0.0 1.9 2 THAP THAP domain ------ inclusion threshold ------ 0.15 12.5 0.4 0.33 11.4 0.4 1.5 1 DUF7191 Family of unknown function (DUF7191) Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 1.8e-09 2.3e-05 1 63 [. 5 74 .. 5 114 .. 0.77 2 ? -2.3 0.0 0.82 1.1e+04 3 21 .. 147 162 .. 146 188 .. 0.52 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.8e-09 THAP 1 CavpgCknkskskskkkvsfhrfP............kdkerrkkWlknikredlekkkkkk.srvCskHFeeelek 63 C v gC+n+ +++++k ++r+P err+ W + i+re l + + rvC +HF +++ FUN_000310-T1 5 CEVLGCSNRFNREKDK--GYYRIPaivsrskpkkqaFSVERRATWFARIRREYLVGDAT-DfFRVCRDHF---ISG 74 999*****86655554..8999999999988887774557888*********9999888.458*******...333 PP == domain 2 score: -2.3 bits; conditional E-value: 0.82 THAP 3 vpgCknkskskskkkvsfh 21 v+gC+++ + + +++ + FUN_000310-T1 147 VKGCQSEITID---QITGF 162 67777732222...13333 PP >> DUF7191 Family of unknown function (DUF7191) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.4 2.6e-05 0.33 22 45 .. 168 190 .. 162 195 .. 0.78 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 2.6e-05 DUF7191 22 dLwEDmdrLNaLYEElmWeheevL 45 LwE m +LN LYEE e ++ + FUN_000310-T1 168 SLWEKM-KLNSLYEESFREDNDKV 190 69****.7*******887776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (198 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 847 (0.0331572); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1963.73 // Query: FUN_000311-T1 [L=207] Description: FUN_000311 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.026 14.7 0.6 0.043 14.1 0.1 1.7 2 HTH_animal Animal helix-turn-helix domain 0.073 13.6 0.2 0.82 10.3 0.0 2.3 2 DUF7083 Domain of unknown function (DUF7083) Domain annotation for each model (and alignments): >> HTH_animal Animal helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 0.7 9e+03 33 48 .. 45 60 .. 39 61 .. 0.69 2 ? 14.1 0.1 3.4e-06 0.043 4 59 .. 124 180 .. 121 181 .. 0.86 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 0.7 HTH_animal 33 dfekelkllkrilleN 48 f++ ++++ + + N FUN_000311-T1 45 QFSNTFRYIDDLFSIN 60 5777888888777666 PP == domain 2 score: 14.1 bits; conditional E-value: 3.4e-06 HTH_animal 4 hfnSnHPrhyKrniirtllrRairicspe.dfekelkllkrilleNGYplkfIkkti 59 h +Sn P + ++ +++l R ric+++ df + l+ l+ l++ G+ ++ ++t+ FUN_000311-T1 124 HMDSNIPANPAYAVYISQLVRYARICTSKvDFMNRLRGLSLRLRQQGFITNLLQRTF 180 567778888888999***********7777***************999999888886 PP >> DUF7083 Domain of unknown function (DUF7083) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 0.062 7.9e+02 64 88 .. 34 58 .. 17 60 .. 0.66 2 ? 10.3 0.0 6.4e-05 0.82 19 42 .. 177 200 .. 159 203 .. 0.83 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.062 DUF7083 64 sirdvedieevkfedtvkaLkklFg 88 ++++++ ++ ++f++t + +++lF FUN_000311-T1 34 KTMKHDITKAIQFSNTFRYIDDLFS 58 3334444567999999999999997 PP == domain 2 score: 10.3 bits; conditional E-value: 6.4e-05 DUF7083 19 ektFkkWyaRyeevftedgkeLse 42 + tF+k ++R+ ++ + g++L e FUN_000311-T1 177 QRTFTKFFNRHGLIVVKYGATLRE 200 68********************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (207 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 743 (0.0290859); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2102.90 // Query: FUN_000312-T1 [L=370] Description: FUN_000312 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-24 85.2 17.9 5.6e-14 52.6 1.6 2.8 3 fn3 Fibronectin type III domain 3.6e-09 37.3 3.2 0.0019 19.0 0.1 2.7 3 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.00074 19.8 11.8 0.023 15.0 1.4 2.9 3 Tissue_fac Tissue factor 0.0066 17.1 8.7 1.1 9.9 0.5 3.4 2 fn3_2 Fibronectin type III domain ------ inclusion threshold ------ 0.01 16.4 3.7 3.4 8.3 0.2 3.4 3 Fn3_VIN3 VIN3-like, fibronectin type-III domain 0.014 16.2 2.2 1 10.1 0.1 3.0 3 Interfer-bind Interferon-alpha/beta receptor, fibronect 0.089 13.3 0.6 1.8 9.1 0.0 2.8 3 NDNF Neuron-derived neurotrophic factor, first Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.2 1.8 6.7e+03 49 49 .. 88 88 .. 58 123 .. 0.61 2 ! 52.6 1.6 1.5e-17 5.6e-14 2 82 .. 158 246 .. 156 248 .. 0.88 3 ! 42.1 3.7 2.9e-14 1.1e-10 2 77 .. 257 340 .. 256 347 .. 0.84 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.8 fn3 49 t 49 t FUN_000312-T1 88 T 88 1 PP == domain 2 score: 52.6 bits; conditional E-value: 1.5e-17 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp..kne....tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ ++ng i Y+v+y+ +++ v+ + ++++tl+gLk +t+Y+++V a + +G g s+p+ FUN_000312-T1 158 PPVNVSGHNTSSTSIFVHWNQVpteHQNGAIMYYTVTYKAlpSGSvqtrSVSAP-SNQMTLSGLKKYTNYSITVFATTIKGAGNVSAPIF 246 788*****************999**9**************64333655666666.999*****************************997 PP == domain 3 score: 42.1 bits; conditional E-value: 2.9e-14 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp......kne.tvpgsretsvtltgLkpgteYevrVqavngaGegee 77 +P n+t + tsts+ v+W++ +ng i +Y+v+y+ ++ v + +t+ tltgL+++t Y+++V a +++G+g+ FUN_000312-T1 257 SPANVTG-NSTSTSIIVQWEHVpssYQNGVILHYTVTYYSwyysrfLQTvIVLAP-TTQTTLTGLNQSTIYSISVSASTSKGDGPA 340 6888888.9************999*99************9875444222456666.89*************************976 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 4.3 1.6e+04 47 57 .. 129 139 .. 100 153 .. 0.46 2 ! 19.0 0.1 5.1e-07 0.0019 15 73 .. 183 241 .. 167 254 .. 0.79 3 ! 18.1 0.3 9.6e-07 0.0035 18 76 .. 284 343 .. 265 353 .. 0.81 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 4.3 FN3_DSCAM-DSCAML_C 47 lviedLkpatw 57 + ++ +pa FUN_000312-T1 129 YPFTTVSPAVS 139 22444444444 PP == domain 2 score: 19.0 bits; conditional E-value: 5.1e-07 FN3_DSCAM-DSCAML_C 15 dggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGstea 73 +++ i++++v y+ + + ++ s +++++++++++Lk t Y+++v A+ G+ + FUN_000312-T1 183 HQNGAIMYYTVTYKALPSGSVQTRSVSAPSNQMTLSGLKKYTNYSITVFATTIKGAGNV 241 45678******************999************************988776654 PP == domain 3 score: 18.1 bits; conditional E-value: 9.6e-07 FN3_DSCAM-DSCAML_C 18 Cpilsfvveyrkkgeeewilvsnn.keqeklviedLkpatwYelkvtAhneaGsteaeye 76 il+++v y ++ +++++ ++++++++++L+++t Y+++v+A + G a y FUN_000312-T1 284 GVILHYTVTYYSWYYSRFLQTVIVlAPTTQTTLTGLNQSTIYSISVSASTSKGDGPAAYI 343 4699************9998765438899***********************99877763 PP >> Tissue_fac Tissue factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 1.2 4.5e+03 26 43 .. 98 115 .. 76 123 .. 0.72 2 ! 10.7 1.2 0.00014 0.51 7 99 .. 141 233 .. 135 241 .. 0.60 3 ! 15.0 1.4 6.2e-06 0.023 15 61 .. 248 298 .. 240 323 .. 0.75 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 1.2 Tissue_fac 26 qnvtfkstnfkniLtWep 43 ++++++s+ + L+W+ FUN_000312-T1 98 SSISVQSSRETESLQWKI 115 467778888888888877 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00014 Tissue_fac 7 vllllalasaavtpelpaPqnvtfkstnfkni.LtWepgqnsp...edvvYtVqyktyksedwkevekCtniteteCdlteetkdltekylarVra 98 vl ++ + + ++P nv+ + t ++i ++W+ ++ ++ +YtV+yk s++ + ++++ + +t + ++ + +y V a FUN_000312-T1 141 VLTTTVSSNTGPQRPSAPPVNVSGHNTSSTSIfVHWNQVPTEHqngAIMYYTVTYKALPSGSVQTR----SVSAPSNQMTLSGLKKYTNYSITVFA 232 4444444444445555677788877766666559***8655551135689******5555555444....44555555555555567777777776 PP Tissue_fac 99 e 99 + FUN_000312-T1 233 T 233 6 PP == domain 3 score: 15.0 bits; conditional E-value: 6.2e-06 Tissue_fac 15 saavtpelpaPqnvtfkstnfkniLtWepgqnsped...vvYtVqyk.tyk 61 +++ + ++P nvt st + i++We +++s ++ +YtV+y y+ FUN_000312-T1 248 VTDEDTPSASPANVTGNSTSTSIIVQWEHVPSSYQNgviLHYTVTYYsWYY 298 456667789********************888775523378****985444 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.5 0.00031 1.1 2 78 .. 154 237 .. 153 249 .. 0.67 2 ! 8.4 2.4 0.00093 3.4 6 89 .] 258 347 .. 252 347 .. 0.66 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00031 fn3_2 2 kPkaPvlkv..knvtqtsvvleWdklelat...aklksLslykngqrlgkip..nplkntstKlsgLsvdteyefqlvlkttaG 78 +P+aP ++v +n+ ts+ ++W+++ + a + + yk + ++ ++++ lsgL+ t+y++++ +t G FUN_000312-T1 154 RPSAPPVNVsgHNTSSTSIFVHWNQVPTEHqngAIMYYTVTYKALPSGSVQTrsVSAPSNQMTLSGLKKYTNYSITVFATTIKG 237 79999888733699**********9976541114455556677533222222113445678899*********99998888665 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00093 fn3_2 6 PvlkvknvtqtsvvleWdklelatak...lksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 P n t ts++++W+++ + + l+ + y + + l+++ + +t+t l+gL+ t y++++ +t+ G+ ++ i++ t FUN_000312-T1 258 PANVTGNSTSTSIIVQWEHVPSSYQNgviLHYTVTYYSwyySRFLQTVIVLAPTTQTTLTGLNQSTIYSISVSASTSKGDGPAAYITIAT 347 555567999*********9864433211122222232211122233444556678899*******************9998888888876 PP >> Fn3_VIN3 VIN3-like, fibronectin type-III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.1 0.0021 7.5 8 74 .. 169 231 .. 162 238 .. 0.65 2 ? 8.3 0.2 0.00093 3.4 8 80 .. 265 336 .. 261 347 .. 0.76 3 ? -2.6 0.0 2.5 9.1e+03 66 80 .. 350 364 .. 349 368 .. 0.84 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0021 Fn3_VIN3 8 atsltviLgsedssssssekivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvv 74 +ts+ v+ ++ ++++++ i+ Y++ ++ + t+ + ap +++++sgL+ t+Y++ v FUN_000312-T1 169 STSIFVHWNQV-PTEHQNGAIMYYTVTYKALP---SGSVQTRSVSAPSNQMTLSGLKKYTNYSITVF 231 45555544333.33333445555555444333...3445578899*****************99886 PP == domain 2 score: 8.3 bits; conditional E-value: 0.00093 Fn3_VIN3 8 atsltviLgsedsssssse.kivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvvsfnetr 80 +ts +i++ e++ ss ++ i +Y++ + ++ t ++lap t+ +++gL+ +t Y++ v + ++++ FUN_000312-T1 265 STSTSIIVQWEHVPSSYQNgVILHYTVTYYSWYYSRFL--QTVIVLAPTTQTTLTGLNQSTIYSISVSASTSKG 336 67777888888766655541678899888877655554..4778999*****************9987766655 PP == domain 3 score: -2.6 bits; conditional E-value: 2.5 Fn3_VIN3 66 ateYvfkvvsfnetr 80 +te++f + fn++ FUN_000312-T1 350 NTEFLFSLLDFNGET 364 69*****99999875 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.9 6.9e+03 56 84 .. 42 70 .. 30 86 .. 0.65 2 ? 10.1 0.1 0.00029 1 7 84 .. 159 232 .. 156 244 .. 0.68 3 ? 4.6 0.1 0.015 54 16 86 .. 267 333 .. 258 341 .. 0.58 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.9 Interfer-bind 56 ekkelestnelvvlsdLepnteYCvsVqa 84 ++++l+ ++ +++ +d+ +++Y v+V FUN_000312-T1 42 DTESLQLETVFITKEDVASSSTYFVTVPP 70 45666666667777777777777777755 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00029 Interfer-bind 7 evel.evedkslnvtvkdpetlkegknlslrelyqslqYkvsywknssn.kekkelestnelvvlsdLepnteYCvsVqa 84 v++ ++++s+++ v+ ++++ e +n + + Y+v+y s ++++++ ++++++ls L++ t+Y ++V a FUN_000312-T1 159 PVNVsGHNTSSTSIFVHWNQVPTEHQNGAI------MYYTVTYKALPSGsVQTRSVSAPSNQMTLSGLKKYTNYSITVFA 232 455534555566666666664433333322......567777766554446999999*****************999977 PP == domain 3 score: 4.6 bits; conditional E-value: 0.015 Interfer-bind 16 slnvtvkdpetlkegknlslrelyqslqYkvsywknssn..kekkelestnelvvlsdLepnteYCvsVqaes 86 s+++ v+ + ++ +s ++ + l Y+v+y + + ++ + ++++ +l+ L+++t Y +sV+a+ FUN_000312-T1 267 STSIIVQWEHVP-----SSYQNGVI-LHYTVTYYSWYYSrfLQTVIVLAPTTQTTLTGLNQSTIYSISVSAST 333 555555555433.....33333334.5555555444433233334444566666999********99999943 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.0005 1.8 88 109 .. 212 233 .. 161 244 .. 0.79 2 ? -2.7 0.0 2.2 7.9e+03 2 19 .. 271 289 .. 270 295 .. 0.75 3 ? 1.0 0.0 0.16 5.7e+02 88 119 .. 311 342 .. 301 349 .. 0.81 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0005 NDNF 88 ktvqtvseLkpdtqYyfdvFav 109 +++t+s+Lk+ t+Y ++vFa FUN_000312-T1 212 SNQMTLSGLKKYTNYSITVFAT 233 5899****************96 PP == domain 2 score: -2.7 bits; conditional E-value: 2.2 NDNF 2 tlkWkpsksv.ldkhaveY 19 +++W++ +s ++ +Y FUN_000312-T1 271 IVQWEHVPSSyQNGVILHY 289 7999999987777666676 PP == domain 3 score: 1.0 bits; conditional E-value: 0.16 NDNF 88 ktvqtvseLkpdtqYyfdvFavdqkrntstay 119 +t++t+++L+++t Y ++v a +k +ay FUN_000312-T1 311 TTQTTLTGLNQSTIYSISVSASTSKGDGPAAY 342 6899***********99998877776666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (370 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 881 (0.0344882); expected 510.9 (0.02) Passed bias filter: 388 (0.0151889); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3713.65 // Query: FUN_000313-T1 [L=1163] Description: FUN_000313 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-48 163.2 44.4 3.7e-13 50.0 5.1 5.1 5 D8C_UMOD Uromodulin-like, D8C domain 8.8e-45 151.3 22.8 1.5e-11 44.8 0.1 4.4 4 fn3 Fibronectin type III domain 1.2e-13 51.6 13.7 0.0035 18.2 0.3 5.1 5 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 1.1e-07 32.6 1.3 0.00012 22.8 0.6 2.8 2 CUB CUB domain 0.00062 20.4 13.3 1.6 9.5 0.0 5.4 4 fn3_2 Fibronectin type III domain 0.0066 17.5 46.5 0.0073 17.4 0.5 5.7 6 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai ------ inclusion threshold ------ 0.023 15.0 14.7 0.3 11.4 1.2 4.0 4 Tissue_fac Tissue factor 0.6 10.7 4.3 37 5.0 0.1 3.5 4 Phage_r1t_holin Putative lactococcus lactis phage r1t hol 7.3 6.8 19.5 0.4 10.9 3.8 3.1 3 Ezh2_MCSS_fung Fungal MCSS domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.1 3.5 8.8e-15 2.5e-11 4 79 .. 133 211 .. 130 219 .. 0.81 2 ! 50.0 5.1 1.3e-16 3.7e-13 9 87 .. 268 348 .. 261 349 .. 0.83 3 ? -3.5 0.1 6.1 1.7e+04 36 57 .. 625 646 .. 609 657 .. 0.72 4 ! 41.2 3.0 7e-14 2e-10 4 79 .. 722 800 .. 719 808 .. 0.81 5 ! 49.0 5.1 2.5e-16 7.2e-13 9 87 .. 857 938 .. 850 939 .. 0.79 Alignments for each domain: == domain 1 score: 44.1 bits; conditional E-value: 8.8e-15 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm ++c sc tn+ wl g hpt+ +g+v rn+c +h +cc s+ i v+ c g fyvy + p FUN_000313-T1 133 FSGGAGTQMAEACPKMYSCSTNSSGWLNGTHPTVAEGIVQRNVCfshrvSHSFYDCC-NSSKNISVRNC-GAFYVYRLDPP 211 6678999************************************95333223344566.57888*****9.89****87554 PP == domain 2 score: 50.0 bits; conditional E-value: 1.3e-16 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyef..vrpt..tcnlayc 87 qm dtcv+ cg+ p wlsgghp++ dg v r++c + cc + s i v+ c gfyvy++ v p c yc FUN_000313-T1 268 GTQMADTCVQMRHCGAWYPGWLSGGHPSVSDGAVLRKVCFTGYQWCCQY-STFISVRNCS-GFYVYKLspVVPYyyQCHYRYC 348 57***************************************9999**87.778******6.7****97333442224666666 PP == domain 3 score: -3.5 bits; conditional E-value: 6.1 D8C_UMOD 36 tledgvvsrnfcahwsnnccyf 57 t dg +c+h n+ + FUN_000313-T1 625 TYADGSTPTRMCSHLLGNVIIY 646 6678888888999987776544 PP == domain 4 score: 41.2 bits; conditional E-value: 7e-14 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm + c sc tn+ wl g hpt+ +g+v r++c +h +cc s+ i v+ c g fyvy + p FUN_000313-T1 722 FSGGAGTQMAEVCPKMYSCSTNSSGWLNGTHPTVAEGIVQRKVCfsqrvSHSFFDCCN-SSKNISVRNC-GAFYVYRLDPP 800 6678999***********************************9944333344456665.6888*****9.89****97655 PP == domain 5 score: 49.0 bits; conditional E-value: 2.5e-16 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcah.wsnnccyfqsnpiqvkacpggfyvyef..vrpt..tcnlayc 87 qm dtcv cg+ p wlsgghp++ dg v r++c + + cc s i v+ c gfyvy++ v p c yc FUN_000313-T1 857 GTQMADTCVSMRHCGAWYPGWLSGGHPSVSDGAVLRKVCFTgYHQWCCQ-YSTFISVRNCS-GFYVYKLspVVPYyyQCHYRYC 938 57*************************************7615555665.5889******6.7****97333442224666666 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.8 0.1 5.2e-15 1.5e-11 2 81 .. 362 448 .. 361 451 .. 0.85 2 ! 39.1 3.1 3.2e-13 9.1e-10 2 77 .. 460 543 .. 459 550 .. 0.84 3 ! 37.6 0.1 9.7e-13 2.8e-09 2 81 .. 952 1038 .. 951 1041 .. 0.84 4 ! 40.3 3.3 1.3e-13 3.8e-10 2 78 .. 1050 1134 .. 1049 1140 .. 0.84 Alignments for each domain: == domain 1 score: 44.8 bits; conditional E-value: 5.2e-15 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeesepl 81 +P n+++ +++sts+ v+W++ ++ng + Y+v+yr+ + v + +++ tltgL+ +t+Y+++V a + + g s+p+ FUN_000313-T1 362 PPANVSAYNISSTSIFVQWDQVpaaHQNGAMLYYTVTYRELPSgfrqtvIVAAP-AHQTTLTGLNKYTNYSITVFASTCK-AGNVSAPI 448 89******************9999*9**************55556765556655.899*****************95544.66777776 PP == domain 2 score: 39.1 bits; conditional E-value: 3.2e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp......kne.tvpgsretsvtltgLkpgteYevrVqavngaGegee 77 +P n+t + tsts+ v+W++ ++ng i +Y+v+y+ ++ v + +t+ tltgL+++t Y+++V a +++G g+ FUN_000313-T1 460 SPANVTG-NSTSTSIFVQWEQVpspHQNGVILHYTVTYYSwyysrfLQTvIVLAP-TTQTTLTGLNQSTIYSISVSASTSKGGGPA 543 6888888.9***********9999*99************9875444222456666.89***********************99975 PP == domain 3 score: 37.6 bits; conditional E-value: 9.7e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeesepl 81 +P n++ +++st + v+W++ ++ng + Y+v+yr+ + v + +++ tltgL+ +t+Y+++V a + + g s+p+ FUN_000313-T1 952 PPANVSGYNISSTIIFVQWDQVpaaHQNGAMLYYTVTYRELPSgfrqtvIVAAP-AHQTTLTGLNKYTNYSITVFASTCK-AGNVSAPI 1038 899*****************9999*9**************55556765556655.899*****************95544.66777776 PP == domain 4 score: 40.3 bits; conditional E-value: 1.3e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp......kne.tvpgsretsvtltgLkpgteYevrVqavngaGegees 78 +P n++ + tsts+ v+W++ ++ng+i +Y+v+y+ ++ v + +t+ tltgL+++t Y+++V a +++G+g+ FUN_000313-T1 1050 SPANVSG-NSTSTSIFVQWEQVpspHQNGDILHYTVTYYSwyysrfLQTvIVLAP-TTQTTLTGLNQSTIYSISVSASTSKGDGPAA 1134 6888888.9***********9999*9*************9875444222456666.89*************************9865 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.0 8.3e-05 0.23 17 79 .. 389 452 .. 371 459 .. 0.81 2 ! 15.4 0.1 8.5e-06 0.024 17 75 .. 486 545 .. 467 554 .. 0.80 3 ? -2.7 0.3 3.8 1.1e+04 23 50 .. 575 602 .. 573 605 .. 0.83 4 ! 12.1 0.0 9.6e-05 0.27 17 79 .. 979 1042 .. 961 1049 .. 0.82 5 ! 18.2 0.3 1.2e-06 0.0035 16 82 .. 1075 1142 .. 1057 1147 .. 0.83 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 8.3e-05 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhn.eaGsteaeyefaT 79 + +l+++v yr+ + ++v +++++++++++L+ t Y+++v A +aG +a + + T FUN_000313-T1 389 NGAMLYYTVTYRELPSGFRQTVIVAAPAHQTTLTGLNKYTNYSITVFASTcKAGNVSAPIFIFT 452 55799*********9999999999999*******************986438888777766666 PP == domain 2 score: 15.4 bits; conditional E-value: 8.5e-06 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilvsnn.keqeklviedLkpatwYelkvtAhneaGsteaey 75 + il+++v y ++ +++++ ++++++++++L+++t Y+++v+A + G a y FUN_000313-T1 486 NGVILHYTVTYYSWYYSRFLQTVIVlAPTTQTTLTGLNQSTIYSISVSASTSKGGGPAAY 545 5579*************9998765438899*******************99988766655 PP == domain 3 score: -2.7 bits; conditional E-value: 3.8 FN3_DSCAM-DSCAML_C 23 fvveyrkkgeeewilvsnnkeqeklvie 50 + yr +++ +w + n+ eq klvie FUN_000313-T1 575 YYYYYRYNQTCSWKIMANKGEQVKLVIE 602 55679999999****9999999998886 PP == domain 4 score: 12.1 bits; conditional E-value: 9.6e-05 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhn.eaGsteaeyefaT 79 + +l+++v yr+ + ++v +++++++++++L+ t Y+++v A +aG +a + + T FUN_000313-T1 979 NGAMLYYTVTYRELPSGFRQTVIVAAPAHQTTLTGLNKYTNYSITVFASTcKAGNVSAPIFIFT 1042 45799*********9999999999999*******************986438888777766666 PP == domain 5 score: 18.2 bits; conditional E-value: 1.2e-06 FN3_DSCAM-DSCAML_C 16 ggCpilsfvveyrkkgeeewilvsnn.keqeklviedLkpatwYelkvtAhneaGsteaeyefaTltl 82 ++ il+++v y ++ +++++ ++++++++++L+++t Y+++v+A + G a y T+ + FUN_000313-T1 1075 QNGDILHYTVTYYSWYYSRFLQTVIVlAPTTQTTLTGLNQSTIYSISVSASTSKGDGPAAYITITTGK 1142 55689*************9998765438899*************************999998888755 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.0029 8.1 33 82 .. 2 53 .. 1 67 [. 0.84 2 ! 22.8 0.6 4.4e-08 0.00012 19 79 .. 577 639 .. 557 656 .. 0.84 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0029 CUB 33 vekgksvklkfedfeleeeee..caydyvevrdgeeasskllgkfcGsekpe 82 ++kg++vkl +e + +++ c +++e+++g a++++ ++c + + FUN_000313-T1 2 ANKGEQVKLVIEYMYVNTWCGwsCSCNHLEIQNGTYADASTTTRMCSHLLGN 53 6899*********9999766577***********************654444 PP == domain 2 score: 22.8 bits; conditional E-value: 4.4e-08 CUB 19 keYeenkeCvweirvekgksvklkfedfeleeeee..caydyvevrdgeeasskllgkfcGse 79 Y+ n++C w+i ++kg++vkl +e + ++++ c +ve++ g a+ ++ ++c + FUN_000313-T1 577 YYYRYNQTCSWKIMANKGEQVKLVIEYMYVNSRCGwsCSCGHVEIQLGTYADGSTPTRMCSHL 639 46999**************************776688*************9999999999544 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.0 0.00055 1.6 7 78 .. 365 441 .. 359 452 .. 0.74 2 ? 3.6 1.9 0.037 1.1e+02 9 89 .] 464 550 .. 455 550 .. 0.60 3 ? 4.4 0.0 0.02 58 10 78 .. 958 1031 .. 949 1042 .. 0.72 4 ? 5.3 1.6 0.011 32 11 89 .] 1056 1140 .. 1045 1140 .. 0.64 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00055 fn3_2 7 vlkvknvtqtsvvleWdklelat...aklksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaG 78 +++ n+ ts+ ++Wd++ a a l + y++ g r + i ++ +++t l+gL+ t+y++++ +t FUN_000313-T1 365 NVSAYNISSTSIFVQWDQVPAAHqngAMLYYTVTYRElpsGFRQTVIV-AAPAHQTTLTGLNKYTNYSITVFASTCKA 441 56788*************977652226777778899644467777776.45677899***********9999888643 PP == domain 2 score: 3.6 bits; conditional E-value: 0.037 fn3_2 9 kvknvtqtsvvleWdklelatak...lksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 n t ts+ ++W+++ + l+ + y + + l+++ + +t+t l+gL+ t y++++ +t+ G ++ i++ t FUN_000313-T1 464 VTGNSTSTSIFVQWEQVPSPHQNgviLHYTVTYYSwyySRFLQTVIVLAPTTQTTLTGLNQSTIYSISVSASTSKGGGPAAYITIAT 550 456889999999999885433221113322223221102223334445567788899999999999999999999987777777665 PP == domain 3 score: 4.4 bits; conditional E-value: 0.02 fn3_2 10 vknvtqtsvvleWdklelat...aklksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaG 78 n+ t + ++Wd++ a a l + y++ g r + i ++ +++t l+gL+ t+y++++ +t FUN_000313-T1 958 GYNISSTIIFVQWDQVPAAHqngAMLYYTVTYRElpsGFRQTVIV-AAPAHQTTLTGLNKYTNYSITVFASTCKA 1031 5699999999****9976642226677778899644467777766.45677899***********9999888643 PP == domain 4 score: 5.3 bits; conditional E-value: 0.011 fn3_2 11 knvtqtsvvleWdklelat..aklksLsl.....ykngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 n t ts+ ++W+++ ++ + ++ y ++ l+++ + +t+t l+gL+ t y++++ +t+ G+ ++ i+++t FUN_000313-T1 1056 GNSTSTSIFVQWEQVPSPHqnGDILHYTVtyyswYYSR-FLQTVIVLAPTTQTTLTGLNQSTIYSISVSASTSKGDGPAAYITITT 1140 58899999999998854330033332222111103222.233444455678899*********************99999998887 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.8 1.5 9 2.6e+04 68 79 .. 333 344 .. 331 350 .. 0.81 2 ! 17.4 0.5 2.6e-06 0.0073 7 83 .. 367 439 .. 363 452 .. 0.78 3 ! 8.9 3.5 0.0011 3.2 9 82 .. 467 536 .. 460 546 .. 0.66 4 ? -5.7 2.2 9 2.6e+04 68 79 .. 923 934 .. 921 938 .. 0.82 5 ! 12.6 0.2 7.8e-05 0.22 10 83 .. 960 1029 .. 953 1042 .. 0.77 6 ! 8.6 4.2 0.0014 4.1 9 83 .. 1056 1127 .. 1051 1140 .. 0.73 Alignments for each domain: == domain 1 score: -4.8 bits; conditional E-value: 9 Pur_ac_phosph_N 68 LepgttYyYrvg 79 L+p YyY++ FUN_000313-T1 333 LSPVVPYYYQCH 344 788888****96 PP == domain 2 score: 17.4 bits; conditional E-value: 2.6e-06 Pur_ac_phosph_N 7 sltg.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 s + +sts+ v+W + +++++++++y+ ++++l s + +t+ ++ + h+ tltgL+ t+Y +v +++ FUN_000313-T1 367 SAYNiSSTSIFVQWDQVpaAHQNGAMLYYTVTYRELPSGFRQTVIVA-------APAHQTTLTGLNKYTNYSITVFASTC 439 444557**********744477999*************999998865.......568******************66653 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0011 Pur_ac_phosph_N 9 tgpstsmtvsWrtpeattsp..vvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 +++sts+ v+W + +++ ++ +++y+ ++ +s+ + + + + +++ tltgL+ +t Y +v +++ FUN_000313-T1 467 NSTSTSIFVQWEQVPSPHQNgvILHYTVTY--YSWYYSRFLQ----TVIVLAPTTQTTLTGLNQSTIYSISVSAST 536 348999999999986544441144444444..4333222222....2235688999****************9886 PP == domain 4 score: -5.7 bits; conditional E-value: 9 Pur_ac_phosph_N 68 LepgttYyYrvg 79 L+p YyY++ FUN_000313-T1 923 LSPVVPYYYQCH 934 788888****96 PP == domain 5 score: 12.6 bits; conditional E-value: 7.8e-05 Pur_ac_phosph_N 10 g.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 + +st + v+W + +++++++++y+ ++++l s + +t+ ++ + h+ tltgL+ t+Y +v +++ FUN_000313-T1 960 NiSSTIIFVQWDQVpaAHQNGAMLYYTVTYRELPSGFRQTVIVA-------APAHQTTLTGLNKYTNYSITVFASTC 1029 446888999**997444779999999999999999999888765.......568******************66653 PP == domain 6 score: 8.6 bits; conditional E-value: 0.0014 Pur_ac_phosph_N 9 tg.pstsmtvsWrtp..eattspvvqygtsssa.lsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 ++ +sts+ v+W + +++++ +++y+ ++ + + s++ +t+ + +++ tltgL+ +t Y +v +++s FUN_000313-T1 1056 GNsTSTSIFVQWEQVpsPHQNGDILHYTVTYYSwYYSRFLQTVI-------VLAPTTQTTLTGLNQSTIYSISVSASTS 1127 34489999999999733366888999998875523333443433.......4577899****************98874 PP >> Tissue_fac Tissue factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.24 6.9e+02 20 58 .. 358 400 .. 347 438 .. 0.72 2 ? 11.4 1.2 0.00011 0.3 15 61 .. 451 501 .. 431 523 .. 0.77 3 ? -2.1 0.0 1.7 4.9e+03 39 58 .. 968 990 .. 946 1010 .. 0.66 4 ? 10.1 0.5 0.00027 0.76 15 61 .. 1041 1091 .. 1022 1119 .. 0.77 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.24 Tissue_fac 20 pelpaPqnvtfkstnfkni.LtWepgqnsp...edvvYtVqyk 58 + ++P nv+ + ++i ++W+ +++ + +YtV+y FUN_000313-T1 358 RSSAPPANVSAYNISSTSIfVQWDQVPAAHqngAMLYYTVTYR 400 5567788888766555554389*98665551125689***998 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00011 Tissue_fac 15 saavtpelpaPqnvtfkstnfkniLtWepgqnsped...vvYtVqyk.tyk 61 ++++ + ++P nvt st + ++We +++++++ +YtV+y y+ FUN_000313-T1 451 FTDEDTPSASPANVTGNSTSTSIFVQWEQVPSPHQNgviLHYTVTYYsWYY 501 667777889*******************9766664422279****985444 PP == domain 3 score: -2.1 bits; conditional E-value: 1.7 Tissue_fac 39 LtWepgqnsp...edvvYtVqyk 58 ++W+ +++ + +YtV+y FUN_000313-T1 968 VQWDQVPAAHqngAMLYYTVTYR 990 67887554441125689999997 PP == domain 4 score: 10.1 bits; conditional E-value: 0.00027 Tissue_fac 15 saavtpelpaPqnvtfkstnfkniLtWepgqnsped...vvYtVqyk.tyk 61 ++++ + ++P nv+ st + ++We +++++++ +YtV+y y+ FUN_000313-T1 1041 FTDEDTPSASPANVSGNSTSTSIFVQWEQVPSPHQNgdiLHYTVTYYsWYY 1091 567777889*******************876666443338*****985444 PP >> Phage_r1t_holin Putative lactococcus lactis phage r1t holin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 1.6 4.4e+03 17 46 .. 407 436 .. 405 438 .. 0.88 2 ? 5.0 0.1 0.013 37 16 46 .. 504 534 .. 502 536 .. 0.93 3 ? -1.7 0.0 1.6 4.4e+03 17 46 .. 997 1026 .. 995 1028 .. 0.88 4 ? 5.0 0.1 0.013 37 16 46 .. 1094 1124 .. 1092 1126 .. 0.93 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.6 Phage_r1t_holin 17 aqallalipadavglldvDwvaalsiaalA 46 q+++ + pa ++ l+ ++ si + A FUN_000313-T1 407 RQTVIVAAPAHQTTLTGLNKYTNYSITVFA 436 6999************99999999998877 PP == domain 2 score: 5.0 bits; conditional E-value: 0.013 Phage_r1t_holin 16 aaqallalipadavglldvDwvaalsiaalA 46 + q+++ l p++++ l+ ++ + si++ A FUN_000313-T1 504 FLQTVIVLAPTTQTTLTGLNQSTIYSISVSA 534 679*************************988 PP == domain 3 score: -1.7 bits; conditional E-value: 1.6 Phage_r1t_holin 17 aqallalipadavglldvDwvaalsiaalA 46 q+++ + pa ++ l+ ++ si + A FUN_000313-T1 997 RQTVIVAAPAHQTTLTGLNKYTNYSITVFA 1026 6999************99999999998877 PP == domain 4 score: 5.0 bits; conditional E-value: 0.013 Phage_r1t_holin 16 aaqallalipadavglldvDwvaalsiaalA 46 + q+++ l p++++ l+ ++ + si++ A FUN_000313-T1 1094 FLQTVIVLAPTTQTTLTGLNQSTIYSISVSA 1124 679*************************988 PP >> Ezh2_MCSS_fung Fungal MCSS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.1 5.7 1.6e+04 20 29 .. 24 33 .. 23 34 .. 0.76 2 ? 10.9 3.8 0.00014 0.4 17 45 .. 175 203 .. 170 206 .. 0.93 3 ? 4.7 3.3 0.012 34 17 45 .. 764 792 .. 762 795 .. 0.94 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 5.7 Ezh2_MCSS_fung 20 shsCeHGeyd 29 s sC+H e++ FUN_000313-T1 24 SCSCNHLEIQ 33 669***7775 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00014 Ezh2_MCSS_fung 17 iCfshsCeHGeydadNekrtfSlesiggl 45 +Cfsh H +yd N+ +++S+ ++g + FUN_000313-T1 175 VCFSHRVSHSFYDCCNSSKNISVRNCGAF 203 9************************9975 PP == domain 3 score: 4.7 bits; conditional E-value: 0.012 Ezh2_MCSS_fung 17 iCfshsCeHGeydadNekrtfSlesiggl 45 +Cfs H ++d N+ +++S+ ++g + FUN_000313-T1 764 VCFSQRVSHSFFDCCNSSKNISVRNCGAF 792 8************************9975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1163 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 506 (0.0198082); expected 510.9 (0.02) Passed bias filter: 225 (0.00880799); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.49 # Mc/sec: 9511.48 // Query: FUN_000314-T1 [L=573] Description: FUN_000314 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-23 83.4 21.3 1.8e-13 51.0 5.5 3.0 3 D8C_UMOD Uromodulin-like, D8C domain 4.5e-23 81.7 9.7 9.6e-12 45.4 0.3 2.5 2 fn3 Fibronectin type III domain 3.1e-08 34.3 1.3 0.0024 18.7 0.4 2.6 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.0026 18.4 3.8 0.87 10.3 0.0 3.1 2 fn3_2 Fibronectin type III domain 0.0035 18.4 0.5 0.0035 18.4 0.5 3.4 3 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.2 1.3 6.8e+03 35 57 .. 35 57 .. 17 69 .. 0.70 2 ! 41.9 3.0 2.3e-14 1.2e-10 4 79 .. 133 211 .. 130 219 .. 0.81 3 ! 51.0 5.5 3.5e-17 1.8e-13 9 87 .. 268 348 .. 261 349 .. 0.83 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.3 D8C_UMOD 35 ptledgvvsrnfcahwsnnccyf 57 t dg +c+h n+ + FUN_000314-T1 35 GTYADGSTPTRMCSHLLGNVIIY 57 46678888888898887776544 PP == domain 2 score: 41.9 bits; conditional E-value: 2.3e-14 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm ++c sc tn+ wl g hpt+ +g+v r++c +h +cc s+ i v+ c g fyvy + p FUN_000314-T1 133 FSGGVGTQMAEACPRMYSCSTNSSGWLNGTHPTVAEGIVQRKVCfsqrvSHSFFDCCN-SSKNISVRNC-GAFYVYRLDPP 211 6678899***********************************9944333344456665.6888*****9.89****97655 PP == domain 3 score: 51.0 bits; conditional E-value: 3.5e-17 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyef..vrpt..tcnlayc 87 qm dtcv+ cg+ p wlsgghp++ dg v r++c + cc + s i v+ c gfyvy++ v p c yc FUN_000314-T1 268 GTQMADTCVQMRHCGAWYPGWLSGGHPSVSDGAVLRKVCFTGYQWCCQY-STYISVRNCN-GFYVYKLspVVPYyyQCHYRYC 348 57***************************************9999**98.678******7.7****97333442224666666 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.4 0.3 1.9e-15 9.6e-12 2 82 .. 362 449 .. 361 451 .. 0.87 2 ! 39.1 4.1 1.8e-13 9.1e-10 2 78 .. 460 544 .. 459 550 .. 0.84 Alignments for each domain: == domain 1 score: 45.4 bits; conditional E-value: 1.9e-15 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ +++sts+ v+W++ ++ng + Y+v+yr+ + v + +++ tltgL+ +t+Y+++V a +++ g s+p+ FUN_000314-T1 362 PPANVSGYNISSTSIFVQWDQVpaaHQNGAMLYYTVTYRELPSgfrqtvIVAAP-AHQTTLTGLNKYTNYSITVFASTSK-AGNVSAPIF 449 899*****************9999*9**************55556765556655.899*****************98887.778888875 PP == domain 2 score: 39.1 bits; conditional E-value: 1.8e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp......kne.tvpgsretsvtltgLkpgteYevrVqavngaGegees 78 +P n++ + tsts+ v+W++ +ng i +Y+v+y+ ++ v + +t+ tltgL+++t Y+++V a +++G+g+ FUN_000314-T1 460 SPANVSG-NSTSTSIFVQWEQVpspYQNGVILHYTVTYYSwyysrfLQTvIVLAP-TTQTTLTGLNQSTIYSISVSASTSKGDGPAA 544 6888888.9***********9999999************9875444222456666.89*************************9865 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 1.5e-05 0.078 17 72 .. 389 445 .. 371 454 .. 0.81 2 ! 18.7 0.4 4.7e-07 0.0024 19 82 .. 488 552 .. 467 557 .. 0.84 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.5e-05 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAh.neaGste 72 + +l+++v yr+ + ++v +++++++++++L+ t Y+++v A ++aG + FUN_000314-T1 389 NGAMLYYTVTYRELPSGFRQTVIVAAPAHQTTLTGLNKYTNYSITVFAStSKAGNVS 445 55799*********9999999999999*******************88526788765 PP == domain 2 score: 18.7 bits; conditional E-value: 4.7e-07 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnn.keqeklviedLkpatwYelkvtAhneaGsteaeyefaTltl 82 il+++v y ++ +++++ ++++++++++L+++t Y+++v+A + G a y T+ + FUN_000314-T1 488 VILHYTVTYYSWYYSRFLQTVIVlAPTTQTTLTGLNQSTIYSISVSASTSKGDGPAAYITITTGK 552 699************9998765438899*************************999998888755 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.0 0.00017 0.87 9 78 .. 367 441 .. 359 450 .. 0.75 2 ! 5.2 2.5 0.0065 33 11 89 .] 466 550 .. 455 550 .. 0.63 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00017 fn3_2 9 kvknvtqtsvvleWdklelat...aklksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaG 78 + n+ ts+ ++Wd++ a a l + y++ g r + i ++ +++t l+gL+ t+y++++ +t+ FUN_000314-T1 367 SGYNISSTSIFVQWDQVPAAHqngAMLYYTVTYRElpsGFRQTVIV-AAPAHQTTLTGLNKYTNYSITVFASTSKA 441 55699***********977652226777778899644467777776.45677899*************99999843 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0065 fn3_2 11 knvtqtsvvleWdklelatak...lksLslykn...gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikvrt 89 n t ts+ ++W+++ + l+ + y + + l+++ + +t+t l+gL+ t y++++ +t+ G+ ++ i+++t FUN_000314-T1 466 GNSTSTSIFVQWEQVPSPYQNgviLHYTVTYYSwyySRFLQTVIVLAPTTQTTLTGLNQSTIYSISVSASTSKGDGPAAYITITT 550 578888888888887532221111222222222110222333444556788999*******************999999998887 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 1.7 4.8 2.4e+04 67 79 .. 332 344 .. 327 350 .. 0.82 2 ! 18.4 0.5 6.9e-07 0.0035 10 83 .. 370 439 .. 363 451 .. 0.82 3 ! 7.6 5.1 0.0016 8.1 10 83 .. 467 537 .. 460 550 .. 0.64 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 4.8 Pur_ac_phosph_N 67 gLepgttYyYrvg 79 +L+p YyY++ FUN_000314-T1 332 KLSPVVPYYYQCH 344 5888889****96 PP == domain 2 score: 18.4 bits; conditional E-value: 6.9e-07 Pur_ac_phosph_N 10 g.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 + +sts+ v+W + +++++++++y+ ++++l s + +t+ ++ + h+ tltgL+ t+Y +v +++s FUN_000314-T1 370 NiSSTSIFVQWDQVpaAHQNGAMLYYTVTYRELPSGFRQTVIVA-------APAHQTTLTGLNKYTNYSITVFASTS 439 5579*********744477999*************999998865.......568******************88875 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0016 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattsp..vvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens 83 + +sts+ v+W + +++ ++ +++y+ ++ +s+ + + + + +++ tltgL+ +t Y +v +++s FUN_000314-T1 467 NsTSTSIFVQWEQVPSPYQNgvILHYTVTY--YSWYYSRFLQ----TVIVLAPTTQTTLTGLNQSTIYSISVSASTS 537 347888888888876553331144444443..3332221111....2225688999****************98874 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (573 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 677 (0.0265023); expected 510.9 (0.02) Passed bias filter: 347 (0.0135839); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.41u 0.94s 00:00:01.35 Elapsed: 00:00:00.65 # Mc/sec: 3580.36 // Query: FUN_000315-T1 [L=661] Description: FUN_000315 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-23 83.7 15.5 5.7e-12 46.1 4.8 2.8 2 D8C_UMOD Uromodulin-like, D8C domain 4.6e-21 75.3 9.8 6.1e-11 42.9 1.3 2.4 2 fn3 Fibronectin type III domain 1.3e-08 35.6 0.5 0.0061 17.4 0.1 2.8 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.00051 20.6 0.3 0.93 10.2 0.1 2.8 2 fn3_2 Fibronectin type III domain Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.4 2.9 1.3e-14 8.3e-11 4 79 .. 133 211 .. 130 219 .. 0.82 2 ! 46.1 4.8 9e-16 5.7e-12 9 87 .. 311 390 .. 304 391 .. 0.87 Alignments for each domain: == domain 1 score: 42.4 bits; conditional E-value: 1.3e-14 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyefvrp 79 f g qm ++c sc tn+ wl g hpt+ +g+v r++c +h +cc s+ i v+ c g fyvy + p FUN_000315-T1 133 FSGGAGTQMAEACPKMYSCSTNSSGWLNGTHPTVAEGIVQRKVCfsqrvSHSFFDCCN-SSKNISVRNC-GAFYVYRLDPP 211 6678999***********************************9944333344456665.6888*****9.89****87554 PP == domain 2 score: 46.1 bits; conditional E-value: 9e-16 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyef..vrp.ttcnlayc 87 qm +tcv cg+ p wlsgghp + dg v r++c cc + s i v+ c ggf +y++ v p +c + yc FUN_000315-T1 311 GTQMAETCVKMRHCGAWYPGWLSGGHPFVSDGAVLRKVCFTGYRGCCQY-STFISVRNC-GGFCIYKLspVYPhNSCHFRYC 390 57*********************************************98.678*****9.7899998744666357999999 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.9 1.3 9.5e-15 6.1e-11 2 82 .. 408 491 .. 407 493 .. 0.91 2 ! 36.9 1.7 7.2e-13 4.6e-09 2 78 .. 502 587 .. 501 593 .. 0.86 Alignments for each domain: == domain 1 score: 42.9 bits; conditional E-value: 9.5e-15 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrp..kne....tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ + i Y+v+yr +++ +v+ + +++ +ltgL+ +t+Y++ V a + +G g s+p+ FUN_000315-T1 408 PPANVSGYNTSSTSVFVQWDQV--PAAILYYTVTYRAlpSGSvqtkNVTAP-ANQTNLTGLNKYTNYSILVFASTWKGAGNISAPIF 491 899*******************..*************75333666788888.899*****************************997 PP == domain 2 score: 36.9 bits; conditional E-value: 7.2e-13 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp.kne.......tvpgsretsvtltgLkpgteYevrVqavngaGegees 78 +P n+t + +sts+ v+W++ +ng i Y+v yr + v + +++ tltgL+++t Y++ V a +++G g+++ FUN_000315-T1 502 SPANVTGNSTSSTSILVKWDQVplpYQNGVILYYTVMYRLyY-NglfpqtvVVAAP-TNQTTLTGLNQSTLYSIAVSASTSKGGGPFT 587 799****9999*********999**99*********999953.3356664555555.899************************9876 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.1 9.6e-07 0.0061 10 71 .. 423 484 .. 415 499 .. 0.84 2 ! 15.5 0.0 3.8e-06 0.024 17 71 .. 529 584 .. 509 597 .. 0.77 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 9.6e-07 FN3_DSCAM-DSCAML_C 10 LsaWkdggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGst 71 + +W++ il+++v yr + + ++ + +++++++ +++L+ t Y++ v A G+ FUN_000315-T1 423 FVQWDQVPAAILYYTVTYRALPSGSVQTKNVTAPANQTNLTGLNKYTNYSILVFASTWKGAG 484 56899999***************9999999999*********************98876654 PP == domain 2 score: 15.5 bits; conditional E-value: 3.8e-06 FN3_DSCAM-DSCAML_C 17 gCpilsfvveyrkkgeeewilv.snnkeqeklviedLkpatwYelkvtAhneaGst 71 + il+++v yr + + + +++++++++++L+++t Y++ v+A + G FUN_000315-T1 529 NGVILYYTVMYRLYYNGLFPQTvVVAAPTNQTTLTGLNQSTLYSIAVSASTSKGGG 584 4579*********99998876515678999*******************9988855 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.001 6.4 9 78 .. 413 482 .. 404 493 .. 0.69 2 ! 10.2 0.1 0.00015 0.93 11 79 .. 509 583 .. 498 593 .. 0.75 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.001 fn3_2 9 kvknvtqtsvvleWdklelataklksLslykn....gqrlgkipnplkntstKlsgLsvdteyefqlvlkttaG 78 + n+ tsv ++Wd++ +a l + y+ +++ +++ p +++t l+gL+ t+y++ + +t G FUN_000315-T1 413 SGYNTSSTSVFVQWDQVP--AAILYYTVTYRAlpsgSVQTKNVTAP--ANQTNLTGLNKYTNYSILVFASTWKG 482 4469999********875..66677777777621113344444444..56788999999999999887777544 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00015 fn3_2 11 knvtqtsvvleWdklelatak...lksL...slykngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGt 79 +++ ts+ ++Wd++ l + l ly ng +++ ++ +++t l+gL+ t y++ + +t+ G FUN_000315-T1 509 NSTSSTSILVKWDQVPLPYQNgviLYYTvmyRLYYNGLFPQTVVVAAPTNQTTLTGLNQSTLYSIAVSASTSKGG 583 455689*********997655222333211157779999999999999999********************9885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (661 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1237 (0.0484243); expected 510.9 (0.02) Passed bias filter: 779 (0.0304952); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.46u 0.69s 00:00:01.14 Elapsed: 00:00:00.51 # Mc/sec: 5212.54 // Query: FUN_000316-T1 [L=480] Description: FUN_000316 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-24 86.1 9.6 4.1e-12 46.6 0.4 2.9 3 fn3 Fibronectin type III domain 6.9e-07 30.0 0.2 0.021 15.6 0.0 2.9 3 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.00063 20.5 0.7 0.0017 19.1 0.7 1.7 1 CUB CUB domain 0.0047 18.0 17.3 0.069 14.2 1.0 3.9 4 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.2 2.7 1.7e+04 12 27 .. 82 99 .. 77 105 .. 0.61 2 ! 46.6 0.4 6.4e-16 4.1e-12 2 82 .. 121 209 .. 120 211 .. 0.88 3 ! 45.1 0.3 2e-15 1.3e-11 2 81 .. 220 308 .. 219 310 .. 0.87 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 2.7 fn3 12 tstsltvsWtpp..dgng 27 +s s+++ W+ ++++ FUN_000316-T1 82 SSISIQLLWESLqwKVES 99 455677888877554444 PP == domain 2 score: 46.6 bits; conditional E-value: 6.4e-16 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ ++ng i Y+v+y + v + +++ tltgL+ +t+Y+++V a + +G g s+p+ FUN_000316-T1 121 PPANVSGHNTSSTSIFVHWDQVpteHQNGAILYYTVTYIALPKglrqtvIVAAP-AHQTTLTGLNKYTNYSISVFASTIKGAGNVSAPIF 209 899*****************999**9**************44434554555555.899*****************************996 PP == domain 3 score: 45.1 bits; conditional E-value: 2e-15 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp..kne......tvpgsretsvtltgLkpgteYevrVqavngaGegeesepl 81 +P +++ + +sts+ v+W++ ++ng i Y+++yr + ++ + +t+ tltgL +gt Y+++V a +++G+g+ s + FUN_000316-T1 220 PPADVSGYNSSSTSIFVQWDQVpaaHQNGAILYYTITYRLffN-GlfpqtvVIDAP-TTQTTLTGLFQGTLYSISVSASTSKGNGTSSSYI 308 899*****************9999****************851.345553455555.9***************************998765 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.0 7.3e-05 0.46 15 74 .. 146 205 .. 130 220 .. 0.78 2 ! 15.6 0.0 3.4e-06 0.021 16 73 .. 246 304 .. 229 313 .. 0.79 3 ? -3.2 0.0 2.5 1.6e+04 27 51 .. 347 371 .. 339 375 .. 0.68 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7.3e-05 FN3_DSCAM-DSCAML_C 15 dggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteae 74 +++ il+++v y + ++v +++++++++++L+ t Y+++v A G+ + + FUN_000316-T1 146 HQNGAILYYTVTYIALPKGLRQTVIVAAPAHQTTLTGLNKYTNYSISVFASTIKGAGNVS 205 356689********9999999999999999********************9887776654 PP == domain 2 score: 15.6 bits; conditional E-value: 3.4e-06 FN3_DSCAM-DSCAML_C 16 ggCpilsfvveyrkkgeeewilv.snnkeqeklviedLkpatwYelkvtAhneaGstea 73 ++ il++++ yr + + + +++++++++++L ++t Y+++v+A + G ++ FUN_000316-T1 246 QNGAILYYTITYRLFFNGLFPQTvVIDAPTTQTTLTGLFQGTLYSISVSASTSKGNGTS 304 45689*********99998876515578899*********************9998654 PP == domain 3 score: -3.2 bits; conditional E-value: 2.5 FN3_DSCAM-DSCAML_C 27 yrkkgeeewilvsnnkeqeklvied 51 yr ++ +w + n+ eq klv+++ FUN_000316-T1 347 YRYNRICSWKIMANKGEQVKLVLKG 371 3445556899988888888888876 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.7 2.6e-07 0.0017 12 76 .. 339 403 .. 329 415 .. 0.84 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 2.6e-07 CUB 12 isspnypkeYeenkeCvweirvekgksvklkfedfeleeeee.caydyvevrdgeeasskllgkfc 76 +s ny Y+ n C w+i ++kg++vkl ++ e + c ++e+++g + + ++c FUN_000316-T1 339 YYSFNYQ-YYRYNRICSWKIMANKGEQVKLVLKGVEFAHCGFsCSCGHLEIQNGTFGDGSSTTRMC 403 5677887.599*************************9954437**********9988877777777 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.2 1.4e+04 23 36 .. 68 81 .. 42 97 .. 0.56 2 ! 13.3 1.4 2.1e-05 0.13 9 82 .. 128 197 .. 122 212 .. 0.76 3 ! 14.2 1.0 1.1e-05 0.069 9 90 .. 228 308 .. 223 310 .. 0.70 4 ? -1.6 0.2 0.92 5.9e+03 37 53 .. 447 463 .. 436 473 .. 0.51 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.2 Pur_ac_phosph_N 23 eattspvvqygtss 36 +a+ ++++ y+tss FUN_000316-T1 68 SASPASIIGYTTSS 81 22233333344333 PP == domain 2 score: 13.3 bits; conditional E-value: 2.1e-05 Pur_ac_phosph_N 9 tg.pstsmtvsWrtp..eattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +sts+ v W + e++++++++y+ ++ al + +t+ + + h+ tltgL+ t+Y +v +++ FUN_000316-T1 128 HNtSSTSIFVHWDQVptEHQNGAILYYTVTYIALPKGLRQTVIV-------AAPAHQTTLTGLNKYTNYSISVFAST 197 55579********9744466888888888888888877666654.......4678****************996654 PP == domain 3 score: 14.2 bits; conditional E-value: 1.1e-05 Pur_ac_phosph_N 9 tgpstsmtvsWrtp.e.attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens...gwsevys 90 +++sts+ v+W + + ++++++++y+ ++ + +++ + + ++ +++ tltgL gt Y +v +++s g+s+ y FUN_000316-T1 228 NSSSTSIFVQWDQVpAaHQNGAILYYTITY---RLFFNGLFPQ---TVVIDAPTTQTTLTGLFQGTLYSISVSASTSkgnGTSSSYI 308 3489*******9973324455555555555...3344554433...223578899*****************999777777777765 PP == domain 4 score: -1.6 bits; conditional E-value: 0.92 Pur_ac_phosph_N 37 salsstatatsstytte 53 ++++t tat+++ tt FUN_000316-T1 447 MSDDTTETATTTETTTR 463 33444444555444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (480 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 830 (0.0324917); expected 510.9 (0.02) Passed bias filter: 448 (0.0175377); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.51 # Mc/sec: 3837.28 // Query: FUN_000317-T1 [L=83] Description: FUN_000317 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 11.4 0.0 0.4 10.6 0.0 1.4 1 P3A Poliovirus 3A protein like Domain annotation for each model (and alignments): >> P3A Poliovirus 3A protein like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 1.6e-05 0.4 2 19 .. 35 52 .. 34 56 .. 0.91 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 1.6e-05 P3A 2 ilqykDLkidiktsPPPe 19 ilq k+L +ikt PPP FUN_000317-T1 35 ILQDKELAEEIKTLPPPA 52 89***************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (83 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 522 (0.0204345); expected 510.9 (0.02) Passed bias filter: 468 (0.0183206); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 837.94 // Query: FUN_000318-T1 [L=999] Description: FUN_000318 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-27 93.5 11.9 4.7e-15 56.0 2.0 2.7 2 D8C_UMOD Uromodulin-like, D8C domain 6.8e-24 84.4 7.4 3.4e-13 50.1 0.4 2.8 2 fn3 Fibronectin type III domain 3e-06 28.0 0.5 9.2e-06 26.4 0.5 1.8 1 CUB CUB domain 4e-05 24.4 3.6 0.069 14.0 0.0 3.4 4 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.00041 20.9 0.6 1.4 9.6 0.1 3.2 3 fn3_2 Fibronectin type III domain ------ inclusion threshold ------ 3.9 7.9 12.0 0.31 11.5 4.9 2.6 2 DUF3439 Domain of unknown function (DUF3439) Domain annotation for each model (and alignments): >> D8C_UMOD Uromodulin-like, D8C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.0 2.6 2.7e-14 1.1e-10 4 76 .. 550 625 .. 547 636 .. 0.83 2 ! 56.0 2.0 1.1e-18 4.7e-15 9 76 .. 684 749 .. 677 758 .. 0.92 Alignments for each domain: == domain 1 score: 42.0 bits; conditional E-value: 2.7e-14 D8C_UMOD 4 fingqsvqmpdtcvdenscgtnaplwlsgghptledgvvsrnfc.....ahwsnnccyfqsnpiqvkacpggfyvyef 76 f g qm ++c sc tn+ wl g hpt+ +g+v r++c +++ +cc +s+ i v+ c g fyvy + FUN_000318-T1 550 FSGGAGTQMAEACTRMYSCSTNSSGWLNGTHPTVAEGIVQRKVCfsqrvSQFFSDCCN-RSKNISVRNC-GSFYVYRL 625 6678999***********************************9944333345567775.7899*****9.89****75 PP == domain 2 score: 56.0 bits; conditional E-value: 1.1e-18 D8C_UMOD 9 svqmpdtcvdenscgtnaplwlsgghptledgvvsrnfcahwsnnccyfqsnpiqvkacpggfyvyef 76 qm dtcv + cg+ p wlsgghp++ dg v r++c s cc+f s i v+ c gfyvy++ FUN_000318-T1 684 GTQMADTCVKQRYCGAWYPGWLSGGHPSVSDGAVLRKVCFTGSWGCCHF-SAFISVRNCN-GFYVYKL 749 57**********************************************9.678******7.7****86 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.1 0.4 8.1e-17 3.4e-13 2 82 .. 192 280 .. 191 282 .. 0.92 2 ! 36.7 1.5 1.2e-12 5e-09 2 79 .. 291 377 .. 290 382 .. 0.84 Alignments for each domain: == domain 1 score: 50.1 bits; conditional E-value: 8.1e-17 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGegeeseple 82 +P n++ + +sts+ v+W++ ++ng i Y+v+y+ + v+ + ++++tl+gLk +t+Y+++V a + +G g s+p+ FUN_000318-T1 192 PPANVSGHNTSSTSIFVHWDQVpaaHQNGAILYYTVTYTALPSayalsrSVSAP-ANQMTLSGLKKYTNYSITVSASTIKGAGNVSAPIF 280 899*****************9999****************66667677788888.899*****************************996 PP == domain 2 score: 36.7 bits; conditional E-value: 1.2e-12 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrp.kne.......tvpgsretsvtltgLkpgteYevrVqavngaGegeese 79 +P n++ + +sts+ v+W++ +ng i Y+++ r + v+ + +t+ tltgL +gt Y+++V a +++G+g s FUN_000318-T1 291 SPANIRGHNTSSTSIFVQWDQVpaaYQNGVILYYTITSRLyY-NglfsqtvVVDAP-TTQTTLTGLFQGTLYSISVSASTRKGNGGSSY 377 6999****************9999*99*********666642.2244553455555.9**************************98875 PP >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.5 2.2e-09 9.2e-06 19 80 .. 410 472 .. 394 488 .. 0.87 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 2.2e-09 CUB 19 keYeenkeCvweirvekgksvklkfedfeleeeee.caydyvevrdgeeasskllgkfcGsek 80 + Y+ n +C w+i ++kg++vkl ++++e + c ++e+++g + ++ ++cGs FUN_000318-T1 410 QYYRYNRTCSWKIMANKGEQVKLVLKSMEFTQCGFsCSCSHLEMQNGTYGDGSNTTRMCGSLL 472 57999************************9965547************************754 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.9 7.9e+03 42 81 .. 129 169 .. 111 175 .. 0.72 2 ! 14.0 0.0 1.6e-05 0.069 16 73 .. 218 275 .. 201 289 .. 0.80 3 ! 9.5 0.0 0.0004 1.7 19 74 .. 320 376 .. 300 382 .. 0.81 4 ? -2.4 0.1 2.1 9e+03 23 52 .. 408 437 .. 406 440 .. 0.82 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.9 FN3_DSCAM-DSCAML_C 42 keqeklviedLkpatwYelkvtAhneaGs.teaeyefaTlt 81 +++++ ++ L++ + +lk++++ + s +++ y f+T++ FUN_000318-T1 129 TSSNSISLQSLWDTESLQLKIQSTIKGDSlSSSIYPFTTVS 169 45678889999999999999998766655144556677765 PP == domain 2 score: 14.0 bits; conditional E-value: 1.6e-05 FN3_DSCAM-DSCAML_C 16 ggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGstea 73 ++ il+++v y + ++ s +++++++++++Lk t Y+++v+A G+ + FUN_000318-T1 218 QNGAILYYTVTYTALPSAYALSRSVSAPANQMTLSGLKKYTNYSITVSASTIKGAGNV 275 4568*********999988888888999*********************988777654 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0004 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilv.snnkeqeklviedLkpatwYelkvtAhneaGsteae 74 il++++ r + + + +++++++++++L ++t Y+++v+A G ++ FUN_000318-T1 320 VILYYTITSRLYYNGLFSQTvVVDAPTTQTTLTGLFQGTLYSISVSASTRKGNGGSS 376 68999999999988887765145688999*******************999976655 PP == domain 4 score: -2.4 bits; conditional E-value: 2.1 FN3_DSCAM-DSCAML_C 23 fvveyrkkgeeewilvsnnkeqeklviedL 52 f yr +++ +w + n+ eq klv++ + FUN_000318-T1 408 FYQYYRYNRTCSWKIMANKGEQVKLVLKSM 437 556689999999***999999999998766 PP >> fn3_2 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.00088 3.7 2 78 .. 188 271 .. 187 283 .. 0.67 2 ! 9.6 0.1 0.00033 1.4 7 87 .. 294 380 .. 287 382 .. 0.79 3 ? -3.7 0.0 4.8 2.1e+04 70 83 .. 979 992 .. 970 995 .. 0.79 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.00088 fn3_2 2 kPkaPvlkv..knvtqtsvvleWdklelat...aklksLslykngqrlgkipnplk..ntstKlsgLsvdteyefqlvlkttaG 78 +P+aP +v +n+ ts+ ++Wd++ a a l + y + +++++++ ++++ lsgL+ t+y++++ +t G FUN_000318-T1 188 RPSAPPANVsgHNTSSTSIFVHWDQVPAAHqngAILYYTVTYTALPSAYALSRSVSapANQMTLSGLKKYTNYSITVSASTIKG 271 57777544422799**********987654111344444555555555555554431167889999999999999999988766 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00033 fn3_2 7 vlkvknvtqtsvvleWdklelataklksL......slykngqrlgkipnplkntstKlsgLsvdteyefqlvlkttaGtyksekikv 87 +++ +n+ ts+ ++Wd++ a + L ly ng ++++ + +t+t l+gL t y++++ +t G+ s i + FUN_000318-T1 294 NIRGHNTSSTSIFVQWDQVPAAYQNGVILyytitsRLYYNGLFSQTVVVDAPTTQTTLTGLFQGTLYSISVSASTRKGNGGSSYIYI 380 578899************987765532221122226999999999999999999*********************999988887776 PP == domain 3 score: -3.7 bits; conditional E-value: 4.8 fn3_2 70 qlvlkttaGtykse 83 ++l t++G+ +s+ FUN_000318-T1 979 VIKLVTASGEMASD 992 57899999999997 PP >> DUF3439 Domain of unknown function (DUF3439) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.6 0.55 2.3e+03 39 69 .. 157 179 .. 130 195 .. 0.57 2 ? 11.5 4.9 7.3e-05 0.31 29 71 .. 771 814 .. 749 820 .. 0.80 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.55 DUF3439 39 pvrsiicpttttttttttttmpttttlpttt 69 + s i p tt + + +t+ ttt FUN_000318-T1 157 SLSSSIYPFTTVSP--------AVSTVLTTT 179 44555555443322........111111111 PP == domain 2 score: 11.5 bits; conditional E-value: 7.3e-05 DUF3439 29 dsakcsgsg.kpvrsiicpttttttttttttmpttttlptttkm 71 +s cs g p + p+tt t tttttt+ ttt + tk FUN_000318-T1 771 SSRYCSSNGsEPPTTGATPSTTDTPTTTTTTITETTTRNSPTKP 814 56778877634777788999999999999999999998888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (999 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 973 (0.0380896); expected 510.9 (0.02) Passed bias filter: 487 (0.0190644); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 9689.39 // Query: FUN_000319-T1 [L=221] Description: FUN_000319 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-29 102.6 0.0 4.4e-29 101.8 0.0 1.4 1 PITH PITH domain 2.3e-26 92.3 0.4 3.7e-26 91.6 0.4 1.2 1 Thioredoxin Thioredoxin 1.7e-05 25.6 0.1 4.4e-05 24.2 0.1 1.7 1 Thioredoxin_2 Thioredoxin-like domain 2.4e-05 25.2 0.0 8.8e-05 23.3 0.0 1.9 1 Thioredoxin_8 Thioredoxin-like 0.00024 21.1 0.0 0.0003 20.8 0.0 1.1 1 OST3_OST6 OST3 / OST6 family, transporter family 0.0016 18.9 0.1 0.0023 18.3 0.1 1.3 1 AhpC-TSA AhpC/TSA family 0.0024 18.4 0.1 0.0057 17.2 0.1 1.6 1 Thioredoxin_7 Thioredoxin-like 0.0092 16.3 0.0 0.015 15.5 0.0 1.3 1 Redoxin Redoxin ------ inclusion threshold ------ 0.043 14.2 0.0 0.065 13.6 0.0 1.3 1 Thioredoxin_9 Thioredoxin 0.055 14.0 0.1 0.15 12.6 0.1 1.6 1 DUF6568 Family of unknown function (DUF6568) Domain annotation for each model (and alignments): >> PITH PITH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 101.8 0.0 1.7e-32 4.4e-29 5 109 .. 122 221 .] 118 221 .] 0.95 Alignments for each domain: == domain 1 score: 101.8 bits; conditional E-value: 1.7e-32 PITH 5 pkgqqsLysqIdlskveclNeaeegslkkvfkpwderldekkyleSdaDeqLlihipFtqsvklhsiliksseeesaPktiklfiNrpn.ldFdda 99 kg+++L +I++s++eclNe++++ +++++ + +yleSd+DeqLli+i F+q vklhs++i++ +++++Pkt+klf N ++ +dFd+a FUN_000319-T1 122 VKGHMDLGLFINKSGCECLNESDDHHFSAAL------AKGPDYLESDCDEQLLISIAFNQGVKLHSLKIQGPDDGRGPKTVKLFSNLTKtMDFDSA 211 678999*************************......8899*********************************************7666****** PP PITH 100 eskkptqeie 109 e +++q++e FUN_000319-T1 212 EGFEAVQTLE 221 *******987 PP >> Thioredoxin Thioredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.6 0.4 1.4e-29 3.7e-26 7 103 .] 16 111 .. 10 111 .. 0.93 Alignments for each domain: == domain 1 score: 91.6 bits; conditional E-value: 1.4e-29 Thioredoxin 7 kenFeeevak.skklvlvdFyApwCGpCkalaPeleelaeelkdkvklakvdvdenkelakkyevegiPtlklfkngkevekyegarekeelaafi 101 ++F++e+ k +klv+vdF A+wCGpCk +aP + +l+ +++ + +++k+dvd+++++a+ ++++++Pt+++fk +v++++ga e ++l+++i FUN_000319-T1 16 YAHFQTEMTKaGSKLVVVDFSASWCGPCKTIAPIFSNLSAKYS-DAVFLKIDVDQCEDIAAAHKISAMPTFLFFKGKVKVDEMTGADE-KKLEEKI 109 5789999999789******************************.999****************************999********99.8999998 PP Thioredoxin 102 kk 103 kk FUN_000319-T1 110 KK 111 75 PP >> Thioredoxin_2 Thioredoxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.1 1.7e-08 4.4e-05 3 94 .. 26 100 .. 24 109 .. 0.74 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 1.7e-08 Thioredoxin_2 3 gngkpvlvvftdpdCpyCkklkkelkelddvtkylkeefefkavniwcakerakafkdieeekelarkygvrgtPtivfldgkeevarlpGy 94 + k v+v f++++C+ Ck + +++l +++ +++++ +i+ ++ + + a +++++++Pt++f+ gk +v++++G+ FUN_000319-T1 26 AGSKLVVVDFSASWCGPCKTIAPIFSNL---SAKY---SDAVFLKIDVDQCE-----------DIAAAHKISAMPTFLFFKGKVKVDEMTGA 100 567899**************99977777...3333...33344444444443...........3678999*************888999998 PP >> Thioredoxin_8 Thioredoxin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 3.5e-08 8.8e-05 2 51 .. 29 71 .. 27 89 .. 0.76 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 3.5e-08 Thioredoxin_8 2 kvvlLyfgaseckkckkflpkLkelykklkkkkkveiVyvsldrdeeefe 51 k+v+++f+as+c +ck ++p+ ++l k++ + V++++d d ++e FUN_000319-T1 29 KLVVVDFSASWCGPCKTIAPIFSNLSAKYS-----DAVFLKIDVD--QCE 71 99***************************7.....4555555555..333 PP >> OST3_OST6 OST3 / OST6 family, transporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 1.2e-07 0.0003 44 134 .. 38 113 .. 3 120 .. 0.81 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 1.2e-07 OST3_OST6 44 rkCelCrefepefelvakswqkdekkeskklfFakldfdegkevfqklglqtvPhlllfpptkgpkksskepdeydfseggfsaeqlaefl 134 + C +C+ ++p f+++++ + +F k+d+d+ +++ + ++ +P++l+f+ + + de+ ++++ e++ +++ FUN_000319-T1 38 SWCGPCKTIAPIFSNLSAKYSDA--------VFLKIDVDQCEDIAAAHKISAMPTFLFFKGKV-------KVDEMTGADEKKLEEKIKKWI 113 46***************999888........9***************************9955.......456666666666667777776 PP >> AhpC-TSA AhpC/TSA family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 9.2e-07 0.0023 24 91 .. 26 91 .. 12 120 .. 0.78 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 9.2e-07 AhpC-TSA 24 kg.kwvvLffypkdwtpvCttelpalaelyeefkekgvevlgvsvdspeshkkfaekeelpfpllsDpk 91 +g k vv+ f ++ w+ +C+t +p +++l +++ ++ l + vd+ e++++ ++ +p+ l+ k FUN_000319-T1 26 AGsKLVVVDFSAS-WCGPCKTIAPIFSNLSAKYS--DAVFLKIDVDQCEDIAAAHKISAMPTFLFFKGK 91 3437788888888.*****************999..7899******99998888776666665555555 PP >> Thioredoxin_7 Thioredoxin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.1 2.2e-06 0.0057 17 81 .. 28 88 .. 16 90 .. 0.73 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 2.2e-06 Thioredoxin_7 17 gkpvlvdlqadwcftCqvlerdvlsdeevkaalrknfvllrldwtsrdenirelde.sgvPvvafl 81 k v vd++a+wc++C++++ + s+ ++k ++ v+l++d+++ ++ + ++ s +P+++f+ FUN_000319-T1 28 SKLVVVDFSASWCGPCKTIAPIF-SNLSAKY---SDAVFLKIDVDQCEDIA-AAHKiSAMPTFLFF 88 566888************98766.4444544...88999999998888744.33334778888887 PP >> Redoxin Redoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 6e-06 0.015 27 61 .. 26 60 .. 17 81 .. 0.81 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6e-06 Redoxin 27 kgkk.vvlnfvpgafcPtCsaehpyleklnelykek 61 +g k vv+ f ++ +c++C++ +p + +l+++y++ FUN_000319-T1 26 AGSKlVVVDFSAS-WCGPCKTIAPIFSNLSAKYSDA 60 4445166677777.*****************99875 PP >> Thioredoxin_9 Thioredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 2.6e-05 0.065 28 109 .. 15 93 .. 8 112 .. 0.83 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.6e-05 Thioredoxin_9 28 lseeleekiksiekkikilvltedwCgDaaqnvPvlakiaelnpnielrillrdenlelmdqyltngkraIPtliildeege 109 +++++++++ +k+ ++ + + wCg + + P++ +++ + + + d+ +++ ++ + a Pt++++ +++ FUN_000319-T1 15 SYAHFQTEMTKAGSKLVVVDFSASWCGPCKTIAPIFSNLSAKYSDAVFLKIDVDQCEDIAAAHKI---SAMPTFLFFKGKVK 93 55667778888999999999*******************99888888878888888888886655...88999999877655 PP >> DUF6568 Family of unknown function (DUF6568) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 5.8e-05 0.15 7 111 .. 17 114 .. 11 116 .. 0.76 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 5.8e-05 DUF6568 7 eefkakvkkk.ek.lfvYvGRPsCgdCnaFepiLkklikeekledklyyvNvdrlredkkawaalkkkydidsvPtlvklkkgkllskldledegG 100 +f++ ++k k + v + Cg C++ pi+ +l++ k +d l+ d ++ +++ +i+ +Pt++ +k + ++ + de+ FUN_000319-T1 17 AHFQTEMTKAgSKlVVVDFSASWCGPCKTIAPIFSNLSA--KYSD------AVFLKIDVDQCEDIAAAHKISAMPTFLFFKGKVKVDEMTGADEKK 104 566666666533335566777789999999999999988..3344......4445667889999****************9998899999999987 PP DUF6568 101 isadelekwls 111 + ++++kw+ FUN_000319-T1 105 L-EEKIKKWIG 114 6.578****95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 523 (0.0204737); expected 510.9 (0.02) Passed bias filter: 472 (0.0184772); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2251.01 // Query: FUN_000320-T1 [L=1103] Description: FUN_000320 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-27 95.7 0.0 1.2e-14 54.9 0.0 2.5 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1.4e-23 84.1 0.6 3.4e-08 33.6 0.0 3.9 3 Beta-prop_WDR5 WDR5 beta-propeller domain 6.5e-19 68.5 0.0 4.8e-08 32.8 0.0 3.0 2 Beta-prop_THOC3 THOC3 beta-propeller domain 3.3e-18 65.8 7.0 0.00031 21.6 0.1 6.4 5 WD40 WD domain, G-beta repeat 7.4e-18 65.1 0.0 9.5e-10 38.5 0.0 2.7 3 WD40_Prp19 Prp19 WD40 domain 2.3e-16 60.5 0.1 9.9e-09 35.4 0.0 3.5 4 Beta-prop_EML_2 Echinoderm microtubule-associated 7e-16 58.9 0.0 2.3e-06 27.6 0.0 3.4 4 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 1.5e-14 54.4 0.0 1.8e-05 24.6 0.0 3.4 3 WD40_WDHD1_1st WDHD1 first WD40 domain 1.7e-14 54.2 0.0 1.1e-05 25.3 0.0 3.1 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 7e-12 45.8 0.0 0.00022 21.2 0.0 2.7 3 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 2.3e-11 43.9 0.0 8.9e-06 25.5 0.0 3.5 4 EIF3I EIF3I 6.1e-11 42.9 0.0 0.012 16.4 0.0 4.6 3 ANAPC4_WD40 Anaphase-promoting complex subunit 3.9e-10 39.7 0.1 6.7e-05 22.5 0.1 2.4 2 WD40_Gbeta G protein beta WD-40 repeat protei 7.7e-10 39.0 0.2 0.0013 18.6 0.1 2.9 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 5.2e-08 32.9 4.4 0.0034 17.1 2.0 4.8 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 6.4e-08 32.5 0.0 0.0054 16.3 0.0 2.8 2 WDR55 WDR55 1.1e-07 31.7 1.0 0.00019 21.1 0.0 2.5 2 WDR90_beta-prop_4th WDR90, 4th beta-propeller 5.7e-07 29.3 0.3 0.0019 17.7 0.0 2.6 2 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 1.5e-06 28.2 0.5 0.0019 18.0 0.0 3.3 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 4.3e-06 26.3 1.6 0.0013 18.1 0.0 3.5 4 Beta-prop_SCAP SCAP Beta-propeller 5.4e-06 25.8 0.0 0.042 13.0 0.0 2.5 2 Beta-prop_IFT140_1st IFT140 first beta-propeller 2.4e-05 24.4 0.3 0.023 14.6 0.0 3.3 3 Beta-prop_EIPR1 EIPR1 beta-propeller 7.3e-05 22.4 0.0 0.74 9.2 0.0 3.5 4 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 9.6e-05 22.6 0.1 0.00036 20.7 0.0 1.9 2 WDR72_alpha-sol WDR72, alpha-solenoid domain 0.00016 21.3 0.0 0.012 15.1 0.0 2.5 2 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.00048 20.1 0.0 1.2 8.9 0.0 3.1 2 Beta-prop_RIG_2nd RIG second beta-propeller 0.00081 19.4 0.0 1.6 8.7 0.0 2.7 3 Beta-prop_EML Echinoderm microtubule-associated 0.0013 18.0 0.0 0.0068 15.6 0.0 2.0 2 Tricorn_2nd Tricorn protease second beta prope 0.002 17.8 0.3 2.5 7.6 0.1 2.6 2 Beta-prop_Aladin Aladin seven-bladed propeller 0.0057 16.0 0.1 0.55 9.4 0.0 2.4 2 Beta-prop_WDR41 WDR41 0.0076 15.9 0.0 1 9.0 0.0 2.5 2 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal ------ inclusion threshold ------ 0.01 15.6 0.0 2.5 7.7 0.0 2.4 2 Beta-prop_HPS5 HPS5 beta-propeller 0.01 15.3 0.0 0.16 11.3 0.0 2.6 2 Beta-prop_VPS8 Vps8 beta-propeller 0.013 15.3 0.0 0.32 10.7 0.1 2.2 2 KNTC1_N KNTC1, N-terminal 0.025 15.0 0.2 9.4 6.8 0.0 3.4 3 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 0.025 14.4 0.2 0.13 12.1 0.1 2.1 2 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 0.073 12.6 0.0 4.3 6.8 0.0 2.9 3 PEP5_VPS11_N PEP5/VPS11 N-terminal 0.13 12.0 0.6 3.1 7.5 0.0 2.6 2 Beta-prop_RSE1_2nd RSE1/DDB1/CPSF1 second beta-propel 0.28 11.8 2.3 1.4 9.5 0.1 3.1 3 PELP1_HEAT PELP1, middle domain Domain annotation for each model (and alignments): >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.9 0.0 1.8e-17 1.2e-14 32 184 .] 19 196 .. 8 196 .. 0.83 2 ! 38.1 0.0 2.6e-12 1.7e-09 33 100 .. 977 1044 .. 950 1054 .. 0.90 Alignments for each domain: == domain 1 score: 54.9 bits; conditional E-value: 1.8e-17 Beta-prop_WDR3_1st 32 vtalaaspdgkklavGyadgsirlwdlesgel.............evtfngHksavtalaf......dkdgsrLasGskDtdiivwDvvae 103 vta p+ + + +G +dgsi + +++++++ + + gH++ vt+l + d++ L+sG++D + +wD+ ++ FUN_000320-T1 19 VTASLYLPSYDYIVCGREDGSIVVTSAARAAItqllqppgsgwpaHRLLLGHRGPVTCLLYpyddyrRYDKEFLVSGGADFAVKLWDIFTG 109 66666677888899999999999999988887445555555555458999*********88332222235678****************** PP Beta-prop_WDR3_1st 104 aglfrLkgHkdqvtsvaflee......kkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtgssdselrvwki 184 l++++ H ++ ++ ++ ++++ s ++D+ + l l++++c+ h v +++ + +++lv+g+sd ++ vw++ FUN_000320-T1 110 DLLYTFSTHAGELLRLLCTPSncsnrvQSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQM 196 ****************99986333333679*******************************************************85 PP == domain 2 score: 38.1 bits; conditional E-value: 2.6e-12 Beta-prop_WDR3_1st 33 talaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGs.kDtdiivwDv 100 ++++ sp++++lavG ++g+i l+dl+s++++ ++ +H+s+vtal+f++d+ Las s D++i+ w + FUN_000320-T1 977 NMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQ-MLPAHSSQVTALSFSPDDRALASYSfGDSKIHFWQT 1044 67899************************998.79*********************8856999999976 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.099 65 226 259 .. 22 55 .. 13 60 .. 0.80 2 ! 18.1 0.0 2.7e-06 0.0018 84 132 .. 65 119 .. 57 125 .. 0.83 3 ! 33.6 0.0 5.2e-11 3.4e-08 96 163 .. 979 1046 .. 973 1090 .. 0.83 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.099 Beta-prop_WDR5 226 efsetggklvvsGsedgkvyiwdlqskeivqkle 259 ++ + +++v+G edg++++ + i+q l+ FUN_000320-T1 22 SLYLPSYDYIVCGREDGSIVVTSAARAAITQLLQ 55 455456689************9999999888775 PP == domain 2 score: 18.1 bits; conditional E-value: 2.7e-06 Beta-prop_WDR5 84 ktlkgHtnyvfcvaF......npkgnllvSGsfDetvrlWdvrtgkclktlpaHs 132 + l gH v+c+ + +++++lvSG++D +v+lWd+ tg +l t++ H+ FUN_000320-T1 65 RLLLGHRGPVTCLLYpyddyrRYDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHA 119 67899999999998833322235689***************************97 PP == domain 3 score: 33.6 bits; conditional E-value: 5.2e-11 Beta-prop_WDR5 96 vaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssy.Dgliriwdtet 163 v+++p++ l+ G+ + ++ l+d+r+++c ++lpaHs +v+a++f+ d + ++s s+ D i+ w+t + FUN_000320-T1 979 VSYSPQSRRLAVGAKNGQIALYDLRSSRC-QMLPAHSSQVTALSFSPDDRALASYSFgDSKIHFWQTGS 1046 899***********************999.68**********************998799999998754 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.8 0.0 7.3e-11 4.8e-08 42 169 .. 67 207 .. 29 228 .. 0.75 2 ! 32.1 0.0 1.2e-10 7.9e-08 176 242 .. 978 1044 .. 929 1068 .. 0.69 Alignments for each domain: == domain 1 score: 32.8 bits; conditional E-value: 7.3e-11 Beta-prop_THOC3 42 lkghtdsVeqla.....wspthpdllatassDktvrlWdvrtgkstatvktkg.eninlawspdG......ktiavgskddtvslidvrtgkvk 123 l gh + V++l ++ ++++l+++++D v+lWd+ tg + t++t+ e + l +p ++i++ +d+ v l+ +r+ k++ FUN_000320-T1 67 LLGHRGPVTCLLypyddYRRYDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAgELLRLLCTPSNcsnrvqSCICSVAQDHSVALLGLRERKCI 160 5677777777762222234567899************************9976155566655543222222456777899**********9986 PP Beta-prop_THOC3 124 ke.ekfkkevnevafspdgkllllttgdgtvevlsypsleevktlka 169 + +++ v+++++ ++l+++++dg+v v++++++ + +++ FUN_000320-T1 161 MLaSVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMETGHLDRCVSG 207 55166889***************************998876555555 PP == domain 2 score: 32.1 bits; conditional E-value: 1.2e-10 Beta-prop_THOC3 176 cvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvsFShdGkllAsas.edktidiasv 242 v+ +p++r lAvG+++ + l+Dl++ c+ +l +++s+v+++sFS+d + lAs s d++i +++ FUN_000320-T1 978 MVSYSPQSRRLAVGAKNGQIALYDLRSSRCQ-MLPAHSSQVTALSFSPDDRALASYSfGDSKIHFWQT 1044 4566666666666666666666666666663.566666666666666666666666533555555554 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.18 1.2e+02 14 37 .. 19 42 .. 8 44 .. 0.83 2 ! 18.9 0.0 3.6e-06 0.0024 7 39 .] 67 105 .. 61 105 .. 0.88 3 ! 14.2 0.1 0.00011 0.07 4 38 .. 160 194 .. 157 195 .. 0.85 4 ? 5.1 0.0 0.081 53 17 39 .] 979 1001 .. 975 1001 .. 0.94 5 ! 21.6 0.1 4.8e-07 0.00031 4 38 .. 1007 1042 .. 1004 1043 .. 0.86 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.18 WD40 14 VtslafspdgsllasgsdDgtvkl 37 Vt+ + p+ +++++g +Dg++ + FUN_000320-T1 19 VTASLYLPSYDYIVCGREDGSIVV 42 666668899************976 PP == domain 2 score: 18.9 bits; conditional E-value: 3.6e-06 WD40 7 lkgHtsgVtslafspdgsl......lasgsdDgtvklWd 39 l gH+++Vt+l ++ d+ l+sg++D vklWd FUN_000320-T1 67 LLGHRGPVTCLLYPYDDYRrydkefLVSGGADFAVKLWD 105 56**999****9777777788***9*************9 PP == domain 3 score: 14.2 bits; conditional E-value: 0.00011 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklW 38 + + H +V ++++ +++l++g+ Dg+v++W FUN_000320-T1 160 IMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVW 194 55556787789***************99******* PP == domain 4 score: 5.1 bits; conditional E-value: 0.081 WD40 17 lafspdgsllasgsdDgtvklWd 39 +++sp ++ la+g+++g + l+d FUN_000320-T1 979 VSYSPQSRRLAVGAKNGQIALYD 1001 789****************9998 PP == domain 5 score: 21.6 bits; conditional E-value: 4.8e-07 WD40 4 lrtlkgHtsgVtslafspdgsllasg..sdDgtvklW 38 + l++H+s Vt+l+fspd++ las + D+++++W FUN_000320-T1 1007 CQMLPAHSSQVTALSFSPDDRALASYsfG-DSKIHFW 1042 56799**999*************988444.******* PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 4.8 3.1e+03 99 123 .. 24 48 .. 16 57 .. 0.61 2 ! 38.5 0.0 1.4e-12 9.5e-10 14 125 .. 84 201 .. 74 215 .. 0.90 3 ! 23.4 0.0 5.7e-08 3.7e-05 137 204 .. 975 1042 .. 908 1046 .. 0.89 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 4.8 WD40_Prp19 99 vhptgdylvsaskDgtwalhdletg 123 p+ dy+v++ +Dg++ +++++ + FUN_000320-T1 24 YLPSYDYIVCGREDGSIVVTSAARA 48 4566777777777777666655544 PP == domain 2 score: 38.5 bits; conditional E-value: 1.4e-12 WD40_Prp19 14 lnpsdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpse......dvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptg 103 +++ dk+ +++GGaD v l+d ++ l t++ h + +++ ps+ + + s ++D++v + e++++++++ h+ v++++ ++ FUN_000320-T1 84 YRRYDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPSNcsnrvqSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALD 179 56678999************************************9976444333579*************************************** PP WD40_Prp19 104 dylvsaskDgtwalhdletgkt 125 d+lv +++Dg++ ++++etg+ FUN_000320-T1 180 DFLVVGCSDGSVYVWQMETGHL 201 *****************99875 PP == domain 3 score: 23.4 bits; conditional E-value: 5.7e-08 WD40_Prp19 137 aitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsas.edgtvklW 204 +++ +++ P l++G k+g++ ++D++s+++ l +hs++vt+l+FS + LAs s d+++ +W FUN_000320-T1 975 RFNMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQ-MLPAHSSQVTALSFSPDDRALASYSfGDSKIHFW 1042 67778888888889****************9985.69*********************87578899999 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1.5 1e+03 43 70 .. 20 47 .. 16 60 .. 0.79 2 ? 1.6 0.0 0.31 2.1e+02 197 265 .. 32 105 .. 30 106 .. 0.77 3 ! 18.3 0.1 2.5e-06 0.0016 10 71 .. 137 199 .. 125 215 .. 0.89 4 ! 35.4 0.0 1.5e-11 9.9e-09 84 154 .. 976 1045 .. 951 1062 .. 0.89 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1.5 Beta-prop_EML_2 43 rsvafspdgkllavGlkdGsvlvldaet 70 ++ + p+ +++++G +dGs++v +a FUN_000320-T1 20 TASLYLPSYDYIVCGREDGSIVVTSAAR 47 5566778999999999999999988765 PP == domain 2 score: 1.6 bits; conditional E-value: 0.31 Beta-prop_EML_2 197 vdrsksekllatgddfGkvklfkyPctkkkakykkykgHsshVtnvrFla......ddsylistGGaDasvfqWk 265 v+ +++++++t+ ++ P + ++++ + gH Vt++ + + d+++l+ GGaD +v W FUN_000320-T1 32 VCGREDGSIVVTSAARAAITQLLQPPGSGWPAHRLLLGHRGPVTCLLYPYddyrryDKEFLV-SGGADFAVKLWD 105 56677888899999999998888888888999999999******999988333333445555.599999999996 PP == domain 3 score: 18.3 bits; conditional E-value: 2.5e-06 Beta-prop_EML_2 10 epqfvTagdDktvrlWdlekkklvakvkle.kearsvafspdgkllavGlkdGsvlvldaetl 71 +++++++ +D++v+l l+++k+++ ++++ +++++++ +++l+vG++dGsv+v++ et+ FUN_000320-T1 137 QSCICSVAQDHSVALLGLRERKCIMLASVHaFPVETIKWRALDDFLVVGCSDGSVYVWQMETG 199 67899******************9999887379************************998875 PP == domain 4 score: 35.4 bits; conditional E-value: 1.5e-11 Beta-prop_EML_2 84 isdikfspdgklLavgshdnkiylYdvskkykkvgklkghssfithlDwsedskylqsns.gdyellfwdak 154 + +++sp+++ Lavg++++ i lYd+ + ++ ++l hss +t l +s d++ l s s gd++++fw++ FUN_000320-T1 976 FNMVSYSPQSRRLAVGAKNGQIALYDL--RSSRCQMLPAHSSQVTALSFSPDDRALASYSfGDSKIHFWQTG 1045 6789**********************8..56999**********************9987699******975 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.2 0.0 0.0014 0.93 185 221 .. 84 118 .. 23 126 .. 0.63 2 ! 24.8 0.0 2.6e-08 1.7e-05 62 165 .. 88 197 .. 81 210 .. 0.83 3 ! 17.4 0.0 4.7e-06 0.0031 22 92 .. 140 208 .. 130 233 .. 0.75 4 ! 27.6 0.0 3.5e-09 2.3e-06 100 164 .. 982 1044 .. 936 1072 .. 0.74 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0014 WD40_CDC20-Fz 185 WcpwkkslLatGGGtaDktirlwntntgkllksvdtg 221 + ++k+ L++GG aD ++lw++ tg ll++++t+ FUN_000320-T1 84 YRRYDKEFLVSGG--ADFAVKLWDIFTGDLLYTFSTH 118 4455667777777..4777777777777777777776 PP == domain 2 score: 24.8 bits; conditional E-value: 2.6e-08 WD40_CDC20-Fz 62 dgelLavGtssgevelwdvekkkklrtleghssrvgalaw...nenl.....lssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrl 149 d+e+L+ G ++ v+lwd+ ++ l t+++h+ + l + n+++ ++s +d+++ +r+++ ++ + h v +kw++ +++ FUN_000320-T1 88 DKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCtpsNCSNrvqscICSVAQDHSVALLGLRERK--CIMLASVHAFPVETIKWRALDDF 181 6789999************************9765444442223222334559999*************97..5678999**************** PP WD40_CDC20-Fz 150 lAsGgndntvkiwdlr 165 l +G++d++v++w+++ FUN_000320-T1 182 LVVGCSDGSVYVWQME 197 *************986 PP == domain 3 score: 17.4 bits; conditional E-value: 4.7e-06 WD40_CDC20-Fz 22 vlavalgssvylwnaetgevkelldlseesdyvtsvkwsedgelLavGtssgevelwdvekkkklrtlegh 92 + +va ++sv l+ +++++ l +++ v +kw +++L+vG+s+g+v++w +e+++ r ++g+ FUN_000320-T1 140 ICSVAQDHSVALLGLRERKCIMLASVH--AFPVETIKWRALDDFLVVGCSDGSVYVWQMETGHLDRCVSGQ 208 456888888888888888888777665..457888888888888888888888888888888776666554 PP == domain 4 score: 27.6 bits; conditional E-value: 3.5e-09 WD40_CDC20-Fz 100 awnenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrllAs.Ggndntvkiwdl 164 + +++ l++G ++g+i +D+r+++ ++l ah+++v+ l++spd+r lAs + d++++ w++ FUN_000320-T1 982 SPQSRRLAVGAKNGQIALYDLRSSRC---QMLPAHSSQVTALSFSPDDRALASySFGDSKIHFWQT 1044 23455688888888888888888764...4678888888888888888888874446777777765 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.022 14 97 138 .. 88 129 .. 70 133 .. 0.80 2 ! 19.8 0.1 7.5e-07 0.00049 94 167 .. 133 206 .. 127 232 .. 0.86 3 ! 24.6 0.0 2.7e-08 1.8e-05 90 166 .. 977 1062 .. 949 1100 .. 0.76 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.022 WD40_WDHD1_1st 97 dgkllaagseDftikvvsvedsskqktleghkapvlsvaldp 138 d+++l++g++Df +k+ ++ +++ t++ h + l + p FUN_000320-T1 88 DKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTP 129 678888888888888888888888888888888777766555 PP == domain 2 score: 19.8 bits; conditional E-value: 7.5e-07 WD40_WDHD1_1st 94 lskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlk 167 ++ ++ + + ++D+++ ++ +++ + ++ + h pv ++ + + +l+ ++DG+v +W++e++ ++++ FUN_000320-T1 133 SNRVQSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMETGHLDRCVS 206 56677888999******************************************************987655554 PP == domain 3 score: 24.6 bits; conditional E-value: 2.7e-08 WD40_WDHD1_1st 90 thialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSss.cDGtvkiWdiesk.........ecvktl 166 + +++s++ + la+g+++ +i ++++ ss+ l h+++v++++++p + laS s +D ++++W+ s+ +cv++ FUN_000320-T1 977 NMVSYSPQSRRLAVGAKNGQIALYDL-RSSRCQMLPAHSSQVTALSFSPDDRALASYSfGDSKIHFWQTGSSlfgmlgsslKCVRSY 1062 678999*******************9.5666779**********************87479******99876444333333333333 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.4 2.6e+02 32 74 .. 9 52 .. 6 57 .. 0.81 2 ! 23.5 0.0 5.8e-08 3.8e-05 171 288 .. 67 196 .. 63 201 .. 0.87 3 ! 25.3 0.0 1.7e-08 1.1e-05 45 109 .. 980 1044 .. 972 1051 .. 0.90 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.4 Beta-prop_WDR3_2nd 32 cirtie.seyalclafvpgdrhvlvgtkdGklevldlasaelle 74 c++++ + +++++++p +++ g +dG++ v++ a a++ + FUN_000320-T1 9 CLNDLGqAIPVTASLYLPSYDYIVCGREDGSIVVTSAARAAITQ 52 777775145688999*******************9998888766 PP == domain 2 score: 23.5 bits; conditional E-value: 5.8e-08 Beta-prop_WDR3_2nd 171 lYGhklPvlsl.....di.ssDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpkt......HylfsagkdkkvkyWDadkf 249 l Gh+ Pv++l d +D +++v+g aD +k+w + GD+ ++ +h ++++ ++p++ + s+++d++v + FUN_000320-T1 67 LLGHRGPVTCLlypydDYrRYDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPSNcsnrvqSCICSVAQDHSVALLGLRER 157 679999999993333322246899*************************************995433333378999*************** PP Beta-prop_WDR3_2nd 250 ekiqtleghagevwalavsskgkfvvsashDksiRlwer 288 ++i+ + ha v ++ ++f+v + +D s+ +w++ FUN_000320-T1 158 KCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQM 196 *************************************96 PP == domain 3 score: 25.3 bits; conditional E-value: 1.7e-08 Beta-prop_WDR3_2nd 45 afvpgdrhvlvgtkdGklevldlasaelletieahegavwsvaltpdekglvtgg.aDkkvkfwef 109 + p+ r + vg+k+G+++++dl+s+++ +++ ah+++v +++ +pd++ l + + +D+k++fw+ FUN_000320-T1 980 SYSPQSRRLAVGAKNGQIALYDLRSSRC-QMLPAHSSQVTALSFSPDDRALASYSfGDSKIHFWQT 1044 5679999*****************9875.89********************997758*******85 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 4.7 3.1e+03 153 178 .. 19 44 .. 12 101 .. 0.79 2 ! 21.2 0.0 3.4e-07 0.00022 129 231 .. 98 205 .. 87 216 .. 0.81 3 ! 21.2 0.0 3.3e-07 0.00022 155 221 .. 978 1043 .. 955 1051 .. 0.82 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 4.7 Beta-prop_WDR36-Utp21_1st 153 italeqspaldvvaiglasGeivlhn 178 +ta p d + g ++G+iv+ FUN_000320-T1 19 VTASLYLPSYDYIVCGREDGSIVVTS 44 66777778889999999999998864 PP == domain 2 score: 21.2 bits; conditional E-value: 3.4e-07 Beta-prop_WDR36-Utp21_1st 129 qGslqlwNirtgkliytfksfksaitaleqsp......aldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDgep 206 + +++lw+i tg l+ytf++ +++ l +p + +++ ++ ++ l ++ + ++ + ++ pv +i r + FUN_000320-T1 98 DFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPsncsnrVQSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRAL-DD 180 55799*************99986666665555333333445555566888*******************99********95.67 PP Beta-prop_WDR36-Utp21_1st 207 vlatgsssGdialwdLekrrlvhvl 231 +l++g+s+G++++w +e+++l ++ FUN_000320-T1 181 FLVVGCSDGSVYVWQMETGHLDRCV 205 9****************99886665 PP == domain 3 score: 21.2 bits; conditional E-value: 3.3e-07 Beta-prop_WDR36-Utp21_1st 155 aleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssGdialwd 221 +++ sp +a+g ++G+i l++++ + + ++ ++vt++sF D++++ + + +i +w FUN_000320-T1 978 MVSYSPQSRRLAVGAKNGQIALYDLRSSRCQMLPAHS-SQVTALSFSPDDRALASYSFGDSKIHFWQ 1043 6677888888999999999999999998888877777.89999999999877666666788888885 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 3.6 2.4e+03 149 175 .. 19 45 .. 13 53 .. 0.69 2 ! 25.5 0.0 1.4e-08 8.9e-06 62 180 .. 87 201 .. 67 214 .. 0.72 3 ? -1.2 0.0 1.9 1.2e+03 89 158 .. 500 568 .. 495 575 .. 0.78 4 ! 13.4 0.0 6.7e-05 0.044 136 207 .. 963 1033 .. 922 1073 .. 0.75 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 3.6 EIF3I 149 vtvalwsaldktiitghedgeiskydl 175 vt++l+ ++i+ g edg+i+ ++ FUN_000320-T1 19 VTASLYLPSYDYIVCGREDGSIVVTSA 45 456667777778888888888765544 PP == domain 2 score: 25.5 bits; conditional E-value: 1.4e-08 EIF3I 62 settllvtgsadntvklWdvetGkelktletkta..vr.svefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalw 154 + + lv+g ad vklWd+ tG+ l t++t++ r ++ s +++++ ++ +v ++ ++ +l +r e++ ++ +v+ v+++ w FUN_000320-T1 87 YDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGelLRlLCTPSNCSNRVQSCICSV-AQDHSVALLGLR------ERKCIMLASVHAFPVETIKW 175 567899**********************99986411231233444444444333333.333344444444......566788888899999***** PP EIF3I 155 saldktiitghedgeiskydlktgek 180 ald+++++g +dg++ ++++tg+ FUN_000320-T1 176 RALDDFLVVGCSDGSVYVWQMETGHL 201 **********************9875 PP == domain 3 score: -1.2 bits; conditional E-value: 1.9 EIF3I 89 tletktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsald 158 +t + +++f +++k+l+l t+ + + +s+ + +d +d+ +e v + ++++ a ws+l FUN_000320-T1 500 VANTLMSLNQISFVPKEKRLALLTTAALEAPSSSSSYDENDKPPGMSEVDVQRA-MNHRAHIKAGWSQLA 568 5677788999****************************9887766655555554.455555678888765 PP == domain 4 score: 13.4 bits; conditional E-value: 6.7e-05 EIF3I 136 eepvlkieveeskvtvalwsaldktiitghedgeiskydlktgeklksvkehekqitdlqlskdktylitas 207 e+ ++++ +++++ +s +++ + +g ++g+i+ ydl++++ ++ +h++q+t l +s+d l + s FUN_000320-T1 963 EKGMTELFPGLCRFNMVSYSPQSRRLAVGAKNGQIALYDLRSSR-CQMLPAHSSQVTALSFSPDDRALASYS 1033 33444455555788999***********************9765.68899*************998877655 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.087 57 48 82 .. 87 121 .. 22 133 .. 0.81 2 ! 16.4 0.0 1.8e-05 0.012 35 72 .. 164 201 .. 139 211 .. 0.82 3 ! 15.5 0.0 3.2e-05 0.021 2 63 .. 980 1040 .. 979 1055 .. 0.80 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.087 ANAPC4_WD40 48 pdGklLavaysdgevrlldvesgklvhslsaksdk 82 d ++L+ + +d v+l d+ +g+l+ ++s+++ + FUN_000320-T1 87 YDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGE 121 57799************************999875 PP == domain 2 score: 16.4 bits; conditional E-value: 1.8e-05 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgkl 72 + + v+ ++W+ +L+v++sdg+v + ++e+g+l FUN_000320-T1 164 SVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMETGHL 201 55667899***************************986 PP == domain 3 score: 15.5 bits; conditional E-value: 3.2e-05 ANAPC4_WD40 2 swcpkmDLiAlatedgevllkRlnwqrvwklseekedsevtslaWkpdGklLav.aysdgevr 63 s++p+ +A++ ++g+++l+ l + r l ++++s+vt+l+++pd + La ++ d++++ FUN_000320-T1 980 SYSPQSRRLAVGAKNGQIALYDLRSSRCQML--PAHSSQVTALSFSPDDRALASySFGDSKIH 1040 7999999999999999999999999999999..899999999999999999984234444444 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.1 1e-07 6.7e-05 103 255 .. 22 196 .. 14 215 .. 0.71 2 ! 14.6 0.0 2.7e-05 0.017 190 245 .. 979 1033 .. 963 1048 .. 0.88 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 1e-07 WD40_Gbeta 103 cayapsgnfvacggldnic........siynlktregn.vrvsrelaghtgylsccrf.......lddnqivtssgdttcalwdietgqqttvfvg 182 y ps +++ cg d +i +l g r l gh g ++c + d + +v+ d ++ lwdi tg+ +f+ FUN_000320-T1 22 SLYLPSYDYIVCGREDGSIvvtsaaraAITQLLQPPGSgWPAHRLLLGHRGPVTCLLYpyddyrrYDKEFLVSGGADFAVKLWDIFTGDLLYTFST 117 567778888888776653301111111234444444431346688899999999975521111114555567777799****************** PP WD40_Gbeta 183 htgdvmslslapdt......rlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsddatcrlfdl 255 h+g+++ l +p + s a d s+ l +re c h +++i + + l+ g d ++ ++++ FUN_000320-T1 118 HAGELLRLLCTPSNcsnrvqSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQM 196 ********9998642221113456778899*************999999999999999998888888888888776665 PP == domain 2 score: 14.6 bits; conditional E-value: 2.7e-05 WD40_Gbeta 190 lslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgs 245 +s +p++r + ga + + l+d+r + c q + h s++ a++f p+ +ala+ s FUN_000320-T1 979 VSYSPQSRRLAVGAKNGQIALYDLRSSRC-QMLPAHSSQVTALSFSPDDRALASYS 1033 6889************************9.68999****************99866 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.0 0.0011 0.72 234 281 .. 65 118 .. 63 122 .. 0.77 2 ! 18.6 0.1 2e-06 0.0013 170 275 .. 90 202 .. 87 218 .. 0.81 3 ! 16.7 0.0 7.2e-06 0.0047 241 310 .. 974 1043 .. 913 1060 .. 0.56 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0011 Beta-prop_WDR36-Utp21_2nd 234 RkfsghknritDltf......spdarWlitasmDstirtwdlpsgkliDvflve 281 R + gh++ +t l + d +l++ + D +++ wd+ +g l+ +f+++ FUN_000320-T1 65 RLLLGHRGPVTCLLYpyddyrRYDKEFLVSGGADFAVKLWDIFTGDLLYTFSTH 118 667788888877776222222457889********************9999875 PP == domain 2 score: 18.6 bits; conditional E-value: 2e-06 Beta-prop_WDR36-Utp21_2nd 170 qvvitagadkklkfwkfkskklletlk........leasisklvlhressllavalddfsilvvDidtrrvvRkfsghknritD 245 + ++++gad +k+w++ + +ll t++ l + s++ + +s + +v +d+s+ ++ + r+++ s h ++ FUN_000320-T1 90 EFLVSGGADFAVKLWDIFTGDLLYTFSthagellrLLCTPSNCSNRVQSCICSV-AQDHSVALLGLRERKCIMLASVHAFPVET 172 6799****************9998766111111114445555555555555555.5789************************* PP Beta-prop_WDR36-Utp21_2nd 246 ltfspdarWlitasmDstirtwdlpsgkli 275 + + + +l+ +D ++ +w++ +g+l FUN_000320-T1 173 IKWRALDDFLVVGCSDGSVYVWQMETGHLD 202 ***************************985 PP == domain 3 score: 16.7 bits; conditional E-value: 7.2e-06 Beta-prop_WDR36-Utp21_2nd 241 nritDltfspdarWlitasmDstirtwdlpsgkliDvflvesaatslslsptgdfLatahvddlgvyLws 310 r + +++sp++r l + i +dl s++ + + +s +t+ls+sp + La+ d ++ w+ FUN_000320-T1 974 CRFNMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQMLPAHSSQVTALSFSPDDRALASYSFGDSKIHFWQ 1043 4444455555555555555555555555555555444445555555555555555555555555555554 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 2.0 5.2e-06 0.0034 81 206 .. 62 198 .. 29 222 .. 0.59 2 ! 7.1 0.0 0.0058 3.8 81 117 .. 1005 1042 .. 962 1048 .. 0.62 3 ! 7.4 0.1 0.0047 3 81 136 .. 1005 1060 .. 1003 1068 .. 0.75 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 5.2e-06 Beta-prop_TEP1_2nd 81 sslsvlrghtgavtccsfsld......GgllatggrdrsllcWdvrvpkaPvlirsllachrdWv......tgcaWtkddllvscssdGsv 159 +++ l gh+g+vtc + d + l +gg d ++ +Wd+ + l++++++ + + + c+ ++ + s ++d sv FUN_000320-T1 62 PAHRLLLGHRGPVTCLLYPYDdyrrydKEFLVSGGADFAVKLWDIFT---GDLLYTFSTHAGELLrllctpSNCSNRVQSCICSVAQDHSV 149 55556667777777766654311111134567777777777777766...33444444333222211222235666666666777777777 PP Beta-prop_TEP1_2nd 160 glWdiekeqrlgkflGhqsavsavv..aveehvvsvgrdGllkvWdlqG 206 +l +++++ ++ h +v ++ a+++ +v dG++ vW+++ FUN_000320-T1 150 ALLGLRERKCIMLASVHAFPVETIKwrALDDFLVVGCSDGSVYVWQMET 198 7777777777777777777776664336666666666677777776543 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0058 Beta-prop_TEP1_2nd 81 sslsvlrghtgavtccsfsldGgllatgg.rdrsllcW 117 s++++l h + vt sfs+d + la+ + d ++ W FUN_000320-T1 1005 SRCQMLPAHSSQVTALSFSPDDRALASYSfGDSKIHFW 1042 34555666666666666666666666544234444444 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0047 Beta-prop_TEP1_2nd 81 sslsvlrghtgavtccsfsldGgllatgg.rdrsllcWdvrvpkaPvlirsllachr 136 s++++l h + vt sfs+d + la+ + d ++ W + +l s l c r FUN_000320-T1 1005 SRCQMLPAHSSQVTALSFSPDDRALASYSfGDSKIHFWQTGSSLFGMLGSS-LKCVR 1060 5678999*******************9773688888998776544444443.34555 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 8.3e-06 0.0054 104 221 .. 86 207 .. 69 221 .. 0.82 2 ! 12.7 0.0 0.0001 0.067 13 77 .. 979 1039 .. 974 1047 .. 0.60 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 8.3e-06 WDR55 104 videnllatGdddGtvklWDlRkkkavmelkehedyisdlvv......deekklLlatsgdGtltvfnirkkklevqseeyeeellslalvkeekk 193 d+++l++G d vklWD+ + + +++++ h l++ ++ + +++++ d +++ + +r++k+ + + + +++ ++ FUN_000320-T1 86 RYDKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCtpsncsNRVQSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDF 181 578999*************************99988888876222222345678999999************************************ PP WDR55 194 vvvGsseGklylfnwgefgahsdrfpgh 221 +vvG s+G++y++++++ h dr+ FUN_000320-T1 182 LVVGCSDGSVYVWQMET--GHLDRCVSG 207 ************99874..345665555 PP == domain 2 score: 12.7 bits; conditional E-value: 0.0001 WDR55 13 isfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvs.kDksi 77 +s++P++ +avg +G++ ly +++ + l +h++++ a++Fs d + l s s D +i FUN_000320-T1 979 VSYSPQSRRLAVGAKNGQIALYDLRSSRC-----QMLPAHSSQVTALSFSPDDRALASYSfGDSKI 1039 66677777777777777777776665433.....34566777777777777777776665223333 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.1 0.0021 1.4 16 128 .. 94 206 .. 86 222 .. 0.92 2 ! 21.1 0.0 2.9e-07 0.00019 222 308 .. 950 1043 .. 941 1046 .. 0.83 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0021 WDR90_beta-prop_4th 16 tcsedGsvrvwslasmelvvqfqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelklhphavaltaiaysadGqtil 105 + + d +v++w + + +l+ f + l l +ps+++ q+++ + d ++ ++ + + + ha + +i++ a + ++ FUN_000320-T1 94 SGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPSNCSNRVQSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDFLV 183 5678999*******************************************************9999999999****************** PP WDR90_beta-prop_4th 106 sgdkdGlvavssprtGvtlrvls 128 g dG v v + tG r +s FUN_000320-T1 184 VGCSDGSVYVWQMETGHLDRCVS 206 **********9999998777665 PP == domain 2 score: 21.1 bits; conditional E-value: 2.9e-07 WDR90_beta-prop_4th 222 evlfyslrkkqvvekiplpffa.....vslslspkarlvavGfaerllrlvdcasgtaqdfaghddsvqlcrfspsgkllftaay..s 302 +++ y+l ++q+ ek f +s sp++r +avG ++ + l d s++ q h+ +v fsp + l + ++ s FUN_000320-T1 950 DIVVYCLDQRQLKEKGMTELFPglcrfNMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQMLPAHSSQVTALSFSPDDRALASYSFgdS 1037 6899********999766555321122458************************************************9987766225 PP WDR90_beta-prop_4th 303 eilvwe 308 +i w+ FUN_000320-T1 1038 KIHFWQ 1043 677775 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.1 0.0014 0.9 236 341 .] 88 196 .. 70 210 .. 0.77 2 ! 17.7 0.0 2.9e-06 0.0019 94 339 .. 979 1042 .. 900 1048 .. 0.64 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0014 WD40_MABP1-WDR62_2nd 236 skklvavacqDrnirvynvssgkqkksfkgsqsedgtllkvqlDpsgl......yvatscsdknlsildfesGecvatvfGhseivtgl 318 +k++++ ++ D ++++++ +g +f + g ll++ ps + + + + d+++++l ++ +c+ h+ v ++ FUN_000320-T1 88 DKEFLVSGGADFAVKLWDIFTGDLLYTFSTHA---GELLRLLCTPSNCsnrvqsCICSVAQDHSVALLGLRERKCIMLASVHAFPVETI 173 56677788889999999999999888886655...567777777665411111133344469999999999999999999999999999 PP WD40_MABP1-WDR62_2nd 319 kFtedcrhlisvsgDsCifvWrl 341 k+ + l+ +D+ ++vW++ FUN_000320-T1 174 KWRALDDFLVVGCSDGSVYVWQM 196 99999999999999999999985 PP == domain 2 score: 17.7 bits; conditional E-value: 2.9e-06 WD40_MABP1-WDR62_2nd 94 lkvspdgkhlasGDrsGniriydletleellkieahdsevlcleyskpetglkllasasRDRlihvfdvekdysllqtlddhsssit 180 ++ sp++++la G ++G+i +ydl++ ++ + ah s+v +l +s FUN_000320-T1 979 VSYSPQSRRLAVGAKNGQIALYDLRSS-RCQMLPAHSSQVTALSFSPD--------------------------------------- 1025 445566666666666666666666543.34555666666666666654....................................... PP WD40_MABP1-WDR62_2nd 181 avkfaeeeeklkliscgaDksilfrkaqktkegvefsrehhvvekttlydmevdaskklvavacqDrnirvynvssgkqkksfkgsq 267 FUN_000320-T1 - --------------------------------------------------------------------------------------- - ....................................................................................... PP WD40_MABP1-WDR62_2nd 268 sedgtllkvqlDpsglyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhlisvs.gDsCifvW 339 r l s s gDs i W FUN_000320-T1 1026 --------------------------------------------------------DRALASYSfGDSKIHFW 1042 ........................................................44444444344444444 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 1.3 8.6e+02 43 69 .. 23 49 .. 14 56 .. 0.81 2 ? 5.8 0.1 0.015 9.8 13 109 .. 96 198 .. 86 233 .. 0.73 3 ! 18.0 0.0 2.9e-06 0.0019 41 96 .. 978 1032 .. 974 1058 .. 0.89 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.3 Beta-prop_WDR90_POC16_2nd 43 afhPskqvfacGfssGvvrvfsveats 69 + Ps + ++cG ++G + v s ++++ FUN_000320-T1 23 LYLPSYDYIVCGREDGSIVVTSAARAA 49 589**************9998877665 PP == domain 2 score: 5.8 bits; conditional E-value: 0.015 Beta-prop_WDR90_POC16_2nd 13 seDetiriWdldtlqqlydfsaseeaPcavafhPsk......qvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdg 90 +D ++++Wd+ t ly fs+++ + Ps+ +++ + ++ v + +++ + ++ + h v ++ + FUN_000320-T1 96 GADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPSNcsnrvqSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALD 179 578999999999999999999988766666666653222220344444567788999999999999999999999999999999 PP Beta-prop_WDR90_POC16_2nd 91 eylysacslGslalydase 109 ++l cs Gs+ ++++++ FUN_000320-T1 180 DFLVVGCSDGSVYVWQMET 198 9999999999988887765 PP == domain 3 score: 18.0 bits; conditional E-value: 2.9e-06 Beta-prop_WDR90_POC16_2nd 41 avafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgeylysa 96 +v++ P+++ +a G ++G + +++++++ + h ++vt+l fspd++ l s FUN_000320-T1 978 MVSYSPQSRRLAVGAKNGQIALYDLRSSRCQM-LPAHSSQVTALSFSPDDRALASY 1032 699***********************999866.6899**************99775 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.0 1.9e-06 0.0013 358 399 .. 90 131 .. 66 144 .. 0.76 2 ? 1.8 0.3 0.17 1.1e+02 323 378 .. 144 200 .. 138 210 .. 0.77 3 ? -3.0 0.0 5 3.3e+03 466 489 .. 296 319 .. 292 322 .. 0.86 4 ? 2.4 0.0 0.11 73 356 395 .. 984 1022 .. 978 1049 .. 0.83 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 1.9e-06 Beta-prop_SCAP 358 mvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvcttsc 399 l sGG d a+ lwd++tG + +h G++ l+ct s FUN_000320-T1 90 EFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPSN 131 4699***********************************884 PP == domain 2 score: 1.8 bits; conditional E-value: 0.17 Beta-prop_SCAP 323 sqdhtvrvyrledscclftlqGhsGgitavy...idqtmvlasGGqdGaiclwdvltGs 378 +qdh+v + l + c++ h+ + ++ +d+ l G dG++ +w + tG FUN_000320-T1 144 AQDHSVALLGLRERKCIMLASVHAFPVETIKwraLDDF--LVVGCSDGSVYVWQMETGH 200 79999999999999999999999988888852225554..5568899999999998885 PP == domain 3 score: -3.0 bits; conditional E-value: 5 Beta-prop_SCAP 466 Gksseaqgvrqllvldnaaivcdf 489 k+ + + q+l++d a++c++ FUN_000320-T1 296 TKCGDRDPEIQVLLFDTEALICNL 319 6899999999************97 PP == domain 4 score: 2.4 bits; conditional E-value: 0.11 Beta-prop_SCAP 356 qtmvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvc 395 q+ la G ++G i l+d l sr + +h +vt+l + FUN_000320-T1 984 QSRRLAVGAKNGQIALYD-LRSSRCQMLPAHSSQVTALSF 1022 6677999999999**999.678999999999999999865 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.0 0.00057 0.37 83 136 .. 148 200 .. 136 218 .. 0.85 2 ! 13.0 0.0 6.4e-05 0.042 61 119 .. 974 1031 .. 953 1047 .. 0.85 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00057 Beta-prop_IFT140_1st 83 evlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWkldqrGr 136 v +l ++++++ l ++h +++++w + Lv g + G++ vW++++ G+ FUN_000320-T1 148 SVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMET-GH 200 56777788899999999******************************9974.55 PP == domain 2 score: 13.0 bits; conditional E-value: 6.4e-05 Beta-prop_IFT140_1st 61 vqvtvlsWHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvs 119 ++ ++s+ P+ + lavg ++G++ ++ ++ +++ lp+ h++++t l++s L+s FUN_000320-T1 974 CRFNMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQMLPA-HSSQVTALSFSPDDRALAS 1031 566788999********************9999988876.************9999987 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.18 1.2e+02 211 234 .. 83 106 .. 79 119 .. 0.83 2 ? 3.1 0.1 0.11 74 171 234 .. 138 196 .. 133 211 .. 0.83 3 ! 14.6 0.0 3.5e-05 0.023 179 280 .] 950 1042 .. 942 1042 .. 0.85 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.18 Beta-prop_EIPR1 211 dfdpakknklltagddgvvlihDi 234 d+ ++ k+ l++ g d v+++Di FUN_000320-T1 83 DYRRYDKEFLVSGGADFAVKLWDI 106 788888999999999999999998 PP == domain 2 score: 3.1 bits; conditional E-value: 0.11 Beta-prop_EIPR1 171 sslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDi 234 s ++ va +++++l+ lR++k +a+v++ v+++ + + ++ + dg v+++ + FUN_000320-T1 138 SCICSVAQDHSVALLGLRERKCIMLASVHAFP----VETIKWRALDDFLVVGC-SDGSVYVWQM 196 678999999***************99998887....89999988877666665.5788888876 PP == domain 3 score: 14.6 bits; conditional E-value: 3.5e-05 Beta-prop_EIPR1 179 esglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLils 270 + ++ +D R+ k+k +e g+ + v ++p+ l+ ++g++ ++D+R ++ + l+ah+ +v++ +f p L FUN_000320-T1 950 DIVVYCLDQRQLKEKG--MTELFPGLCRFNMVSYSPQSRR-LAVGAKNGQIALYDLR------SSRCQMLPAHSSQVTALSFSPDDRALASY 1032 5678999*****9999..889999************8765.5556689*********......788999***************98887766 PP Beta-prop_EIPR1 271 cssdstlkLw 280 + ds+++ w FUN_000320-T1 1033 SFGDSKIHFW 1042 6677777766 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.2 0.0 0.0011 0.74 73 209 .. 19 162 .. 6 172 .. 0.71 2 ? 2.7 0.0 0.11 71 69 102 .. 166 199 .. 154 212 .. 0.76 3 ? 1.2 0.0 0.31 2e+02 72 102 .. 975 1005 .. 947 1012 .. 0.78 4 ! 6.2 0.0 0.0093 6.1 136 192 .. 979 1034 .. 975 1047 .. 0.70 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0011 Beta-prop_CAF1B_HIR1 73 vnvvrfspsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlsws......pdskklisgsvDntai 155 v + + ps +++ g +++ i++ +++ i++l + w ++++l Gh v l + d+++l+sg D ++ FUN_000320-T1 19 VTASLYLPSYDYIVCGREDGSIVVTSAARAA--ITQL---LQPPGSGWPAHRLLLGHRGPVTCLLYPyddyrrYDKEFLVSGGADFAVK 102 5566677788888888888888877666654..3333...3455678999*******999977776511111156789*********** PP Beta-prop_CAF1B_HIR1 156 lWdvekgkklailkdhkgfvqgvawdPkn......qyvatlssDrslrifdiktkkvvar 209 lWd+ g l ++ h g + P+n +++++++ D s+ ++ ++++k++ FUN_000320-T1 103 LWDIFTGDLLYTFSTHAGELLRLLCTPSNcsnrvqSCICSVAQDHSVALLGLRERKCIML 162 ***************998777776666553333325788888888888888888888765 PP == domain 2 score: 2.7 bits; conditional E-value: 0.11 Beta-prop_CAF1B_HIR1 69 hqkavnvvrfspsgelLasgdDesviiiWklkee 102 h +v ++++ +++L g ++ + +W++++ FUN_000320-T1 166 HAFPVETIKWRALDDFLVVGCSDGSVYVWQMETG 199 6667888888888888888888888888887765 PP == domain 3 score: 1.2 bits; conditional E-value: 0.31 Beta-prop_CAF1B_HIR1 72 avnvvrfspsgelLasgdDesviiiWklkee 102 n+v +sp+ + La g +++i ++ l+++ FUN_000320-T1 975 RFNMVSYSPQSRRLAVGAKNGQIALYDLRSS 1005 569********************99988876 PP == domain 4 score: 6.2 bits; conditional E-value: 0.0093 Beta-prop_CAF1B_HIR1 136 lswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlss 192 +s+sp+s++l g+ + ++ l+d++ + + ++l h + v + ++ P ++ +a+ s FUN_000320-T1 979 VSYSPQSRRLAVGAKNGQIALYDLRSS-RCQMLPAHSSQVTALSFSPDDRALASYSF 1034 578888888888887777778887554.45777888888888888888888877763 PP >> WDR72_alpha-sol WDR72, alpha-solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.1 5.3 3.5e+03 62 100 .. 338 375 .. 333 382 .. 0.77 2 ! 20.7 0.0 5.5e-07 0.00036 110 145 .. 594 629 .. 585 646 .. 0.88 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 5.3 WDR72_alpha-sol 62 sekmesvrsKwkssendllntssfyselanekneshvpe 100 s k s+ K k++ ++s++y+ l +kne+h+ + FUN_000320-T1 338 SSKTASATGKRKKTPT-SQQMSASYQALPYQKNETHFVA 375 6788888888888777.5678899999999999998755 PP == domain 2 score: 20.7 bits; conditional E-value: 5.5e-07 WDR72_alpha-sol 110 ssWrdQSVqViEAiQAVLLaEvqrkmktlrktiitt 145 W+d +V EA QA+LLaE++r rk++++t FUN_000320-T1 594 RKWQDRCLEVREAAQAILLAELRRIGSDGRKRVVDT 629 57**********************999999998877 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.074 49 61 112 .. 147 198 .. 129 220 .. 0.81 2 ! 15.1 0.0 1.9e-05 0.012 85 136 .. 977 1027 .. 960 1069 .. 0.80 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.074 Beta-prop_WDR19_1st 61 slvllwdantkktskldtglkdkltfllWskkspiLavGtskGnlllYnkkt 112 ++v l ++++k +l + ++ +++W ++L+vG s G++++++ +t FUN_000320-T1 147 HSVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMET 198 5667777777777777777777888999999999999999999999998776 PP == domain 2 score: 15.1 bits; conditional E-value: 1.9e-05 Beta-prop_WDR19_1st 85 tfllWskkspiLavGtskGnlllYnkktskkipilGkHskkItcgawskenl 136 ++++ s +s LavG ++G+++lY+ ++s+ +l Hs ++t ++s ++ FUN_000320-T1 977 NMVSYSPQSRRLAVGAKNGQIALYDLRSSR-CQMLPAHSSQVTALSFSPDDR 1027 577888888888888888888888888776.567888888888888886553 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0067 4.4 206 249 .. 159 201 .. 86 211 .. 0.68 2 ! 8.9 0.0 0.0019 1.2 5 55 .. 986 1033 .. 976 1046 .. 0.81 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0067 Beta-prop_RIG_2nd 206 kkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepek 249 + as + ++++kw ++ l++ + dg+v+vW++e+++ FUN_000320-T1 159 CIMLASVHAFPVETIKWRALDDFLVVG-CSDGSVYVWQMETGHL 201 34556678889999***9998888887.569*******998765 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0019 Beta-prop_RIG_2nd 5 nkiAlgvsDrrvalldlsklsakklsieslkvkskvlsLaWspdkenLA.fg 55 ++A+g ++++al+dl + +++ l+ +s s+v++L+ spd + LA ++ FUN_000320-T1 986 RRLAVGAKNGQIALYDLRSSRCQMLPAHS----SQVTALSFSPDDRALAsYS 1033 58899999999999999999999888875....7889999999999987455 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 2.3 1.5e+03 195 226 .. 68 105 .. 19 119 .. 0.64 2 ! 7.6 0.0 0.0049 3.2 41 145 .. 99 203 .. 64 212 .. 0.78 3 ! 8.7 0.0 0.0024 1.6 163 226 .. 980 1043 .. 951 1064 .. 0.71 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2.3 Beta-prop_EML 195 kahegsvfsllvlkdg......tllsgggkdgkivawd 226 h+g+v++ll+ d +l++gg d ++ wd FUN_000320-T1 68 LGHRGPVTCLLYPYDDyrrydkEFLVSGGADFAVKLWD 105 47888888886543322222225556668888888887 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0049 Beta-prop_EML 41 phiriWdsetletlavlg..kgefergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhia 134 +++ Wd+ t l ++ +ge+ r +++ + +++ + +++ +++h++ + ++++ ++ + ++ +v +++ ld+ l+v c ++ FUN_000320-T1 99 FAVKLWDIFTGDLLYTFSthAGELLRLLCTPSNCSN--RVQSCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVY 192 567888888777777665224566665555555544..45566666678899999999************************************** PP Beta-prop_EML 135 FWtlegkklek 145 W++e + l++ FUN_000320-T1 193 VWQMETGHLDR 203 ***99988765 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0024 Beta-prop_EML 163 afsengd.vitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdg.tllsgggkdgkivawd 226 ++s++ + G +nG+i +++ ++++ ++ ah+++v++l +++d l s + d ki w+ FUN_000320-T1 980 SYSPQSRrLAVGAKNGQIALYDLRSSRC--QMLPAHSSQVTALSFSPDDrALASYSFGDSKIHFWQ 1043 5554443377899999999998766665..455689999999988887514444444556665555 PP >> Tricorn_2nd Tricorn protease second beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 1.1 7.3e+02 13 62 .. 410 460 .. 408 463 .. 0.74 2 ! 15.6 0.0 1e-05 0.0068 68 147 .. 955 1037 .. 921 1043 .. 0.81 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.1 Tricorn_2nd 13 ialtsRGkaFt..vpawegpvlqlgeksgvryrlvewlndgkrvaavsdeee 62 ++l++RG+ F+ +p w g v ++ +++++ l + +++++ ++ ++d+e FUN_000320-T1 410 FGLVTRGNRFSlmLPGWYGEVCRI-NNEDAETTLRKLSDNEDLLIEIEDTES 460 5799*****9733589********.556777777777777776777777665 PP == domain 2 score: 15.6 bits; conditional E-value: 1e-05 Tricorn_2nd 68 ildadgseka.ltd..edlgrieelkvspdgkkiavannrneLllvdletgeatlidkseegaiedfswspdsrwlA.Ysfpes 147 ld+++ +++ +t+ +l r + ++ sp+++++av+ ++ ++ l+dl + +++ + ++ ++ +s+spd r lA Ysf +s FUN_000320-T1 955 CLDQRQLKEKgMTElfPGLCRFNMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQMLPAHSS-QVTALSFSPDDRALAsYSFGDS 1037 555555555554441145667888999*****************************99888.59**********9997888765 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.6 0.1 0.0038 2.5 101 152 .. 158 205 .. 133 221 .. 0.68 2 ! 7.3 0.0 0.0049 3.2 99 141 .. 1004 1045 .. 979 1083 .. 0.80 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0038 Beta-prop_Aladin 101 saqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvg 152 ++ +L + pv +++W d Lv ++ d s++vW++++ L r FUN_000320-T1 158 KCIMLASVHAFPVETIKWRALDDFLVVGC-SDGSVYVWQMETG---HLDRCV 205 55677777778888999988888888665.5888888887653...344444 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0049 Beta-prop_Aladin 99 sssaqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdva 141 ss +q+L + s vt +++sp+ + L+s s d++i W+ FUN_000320-T1 1004 SSRCQMLPAH-SSQVTALSFSPDDRALASYSFGDSKIHFWQTG 1045 4555666543.4789999*************999999999865 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.00083 0.55 52 113 .. 88 148 .. 63 175 .. 0.74 2 ? 3.6 0.1 0.047 31 51 75 .. 178 201 .. 170 217 .. 0.78 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00083 Beta-prop_WDR41 52 ddfrfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdkt 113 d+ ++s g d v lwd+ tg+ l+ + h+ ++ + +++ s+ + i + + d++ FUN_000320-T1 88 DKEFLVSGGADFAVKLWDIFTGDLLYTFSTHAGELLRLLCTPSNC-SNRVQSCICSVAQDHS 148 33346999************************9998888777654.4444445555555555 PP == domain 2 score: 3.6 bits; conditional E-value: 0.047 Beta-prop_WDR41 51 iddfrfasagddgivflwdvqtgei 75 +ddf + dg+v++w+++tg+ FUN_000320-T1 178 LDDFLVVG-CSDGSVYVWQMETGHL 201 56775554.56899******99975 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.041 27 14 56 .. 167 209 .. 141 222 .. 0.82 2 ! 9.0 0.0 0.0015 1 159 198 .. 976 1015 .. 948 1070 .. 0.90 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.041 Beta-prop_WDR35_TULP_N 14 nvklksvaWnkeqgyiavggedglLkvLklesekkeakakgla 56 ++++ W + ++++ vg++dg + v ++e+ + ++ ++g+ FUN_000320-T1 167 AFPVETIKWRALDDFLVVGCSDGSVYVWQMETGHLDRCVSGQV 209 56689999***************99999999987666555554 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0015 Beta-prop_WDR35_TULP_N 159 lakvewspdgklllfglkegevhvydsegnflsklklkcl 198 + +v++sp+++ l +g k+g++ +yd + + ++ l + FUN_000320-T1 976 FNMVSYSPQSRRLAVGAKNGQIALYDLRSSRCQMLPAHSS 1015 6789**********************99999988887654 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.023 15 40 90 .. 148 198 .. 121 210 .. 0.78 2 ? 7.7 0.0 0.0038 2.5 28 87 .. 984 1043 .. 973 1048 .. 0.75 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.023 Beta-prop_HPS5 40 gvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelni 90 +v ++ + k++ l + + ++ t++ + +d++ v+ s+g v+v+++++ FUN_000320-T1 148 SVALLGLRERKCIMLASVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMET 198 56666666777777777788889999999999****************986 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0038 Beta-prop_HPS5 28 srkflaLGsstGgvyifsrealkllqlltakegaistvaispdedlva.vatsrglvvvve 87 ++ la+G+ +G++ +++ + + q+l+a++++++ +++spd+ +a + +++++ ++ FUN_000320-T1 984 QSRRLAVGAKNGQIALYDLRSSR-CQMLPAHSSQVTALSFSPDDRALAsYSFGDSKIHFWQ 1043 4566999**********988776.5899**************7776661444566666665 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.53 3.5e+02 73 104 .. 174 205 .. 159 216 .. 0.74 2 ? 11.3 0.0 0.00025 0.16 33 126 .. 986 1090 .. 979 1102 .. 0.75 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.53 Beta-prop_VPS8 73 afnadstrllaGyarGqilmwDlsngkllrti 104 + a l++G ++G++ +w +++g+l r + FUN_000320-T1 174 KWRALDDFLVVGCSDGSVYVWQMETGHLDRCV 205 55555566899999999999999999876655 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00025 Beta-prop_VPS8 33 sliavGTshGlvLvFdseqtLklclgstakgaeqgaVsalafnadstrll.aGyarGqilmwDlsng.........kllrtisdahppgt... 112 + +avG +G + ++d + + +l a++ V+al+f+ d l+ + + +i w + ++ k++r+ + p + FUN_000320-T1 986 RRLAVGAKNGQIALYDLRSSRCQMLP-----AHSSQVTALSFSPDDRALAsYSFGDSKIHFWQTGSSlfgmlgsslKCVRSYTTNSPSSKmap 1073 5689************9987443443.....45779*********9999845899999**999999888888888888887777666665566 PP Beta-prop_VPS8 113 ...avlhikFtddptla 126 + + + ++++++++ FUN_000320-T1 1074 allKLIRLVWINHKNVI 1090 55566666666666655 PP >> KNTC1_N KNTC1, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.1 0.00048 0.32 29 98 .. 127 198 .. 110 210 .. 0.83 2 ? 2.0 0.0 0.22 1.4e+02 71 100 .. 977 1006 .. 974 1019 .. 0.86 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00048 KNTC1_N 29 snPklvassssegli.vvadksvslfdeicqsvllt.LsfdsevdvvalsqdgqfLlvgersGnlhlihves 98 ++P+ ++ ++ +++ v+ d+sv+l+ +++++ +v+++++ fL+vg ++G++++ ++e+ FUN_000320-T1 127 CTPSNCSNRVQSCICsVAQDHSVALLGLRERKCIMLaSVHAFPVETIKWRALDDFLVVGCSDGSVYVWQMET 198 578999999999999677899*****98888876551446679***********************998876 PP == domain 2 score: 2.0 bits; conditional E-value: 0.22 KNTC1_N 71 dvvalsqdgqfLlvgersGnlhlihveskk 100 ++v s++++ L+vg ++G++ l++ s++ FUN_000320-T1 977 NMVSYSPQSRRLAVGAKNGQIALYDLRSSR 1006 57899******************9998876 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.014 9.4 12 42 .. 89 119 .. 86 141 .. 0.80 2 ? 4.0 0.2 0.11 72 12 70 .. 137 193 .. 133 197 .. 0.83 3 ? 1.5 0.0 0.64 4.2e+02 9 32 .. 176 199 .. 166 220 .. 0.85 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.014 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkkqvGlFvCea 42 ++ ++s D +vKlWd t ++ F +a FUN_000320-T1 89 KEFLVSGGADFAVKLWDIFTGDLLYTFSTHA 119 57899************99999998888776 PP == domain 2 score: 4.0 bits; conditional E-value: 0.11 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkkqvGlFvCea.pvlvlevnpnpeseleLvcgDklGkvYf 70 ++ i+s ++D++v l ++ k + l +a pv++++ + Lv+g + G vY FUN_000320-T1 137 QSCICSVAQDHSVALLGLRERKCIMLASVHAfPVETIKWR-A--LDDFLVVGCSDGSVYV 193 78999***********999999999998887799999974.3..3447899999999996 PP == domain 3 score: 1.5 bits; conditional E-value: 0.64 Beta-prop_TEP1_C 9 kltddliisAseDrtvKlWdretk 32 + +dd ++ +D +v +W+ et FUN_000320-T1 176 RALDDFLVVGCSDGSVYVWQMETG 199 568999999999*******99885 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.0002 0.13 62 168 .. 89 201 .. 84 210 .. 0.75 2 ? -1.6 0.0 2.9 1.9e+03 18 43 .. 983 1008 .. 950 1023 .. 0.69 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.0002 Beta-prop_ACSF4 62 gklvvvGcydgklycldlatgeilwkfktgd....aiKsspvidsesg..lvvvgsydknlyaldvesgklvwklklggsifsspllskskesv 149 ++++v G+ d + d+ tg++l++f+t + ++p +s++ + + d+++ l ++++k+++ +++ ++ + + + ++++ FUN_000320-T1 89 KEFLVSGGADFAVKLWDIFTGDLLYTFSTHAgellRLLCTPSNCSNRVqsCICSVAQDHSVALLGLRERKCIMLASVHAFPVETIKWRALDDFL 182 6677778888888888888888888888755455556688888776542266667788888888888888888888888888888888888888 PP Beta-prop_ACSF4 150 lvatldGtvaalseesgei 168 +v+ dG+v+ ++e+g++ FUN_000320-T1 183 VVGCSDGSVYVWQMETGHL 201 8888888888888888876 PP == domain 2 score: -1.6 bits; conditional E-value: 2.9 Beta-prop_ACSF4 18 ksselvvvgSHsgkivcvdletgevi 43 +s++++vg g+i+ +dl++++++ FUN_000320-T1 983 PQSRRLAVGAKNGQIALYDLRSSRCQ 1008 34455666666666666666665554 PP >> PEP5_VPS11_N PEP5/VPS11 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.94 6.1e+02 123 151 .. 15 43 .. 8 53 .. 0.89 2 ? 1.1 0.0 0.36 2.3e+02 123 154 .. 166 197 .. 145 209 .. 0.82 3 ? 6.8 0.0 0.0066 4.3 129 200 .. 978 1044 .. 958 1066 .. 0.83 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.94 PEP5_VPS11_N 123 kpfpvsalavsedlsllavGfangsVlli 151 +++pv+a +++ ++++ G ++gs+++ FUN_000320-T1 15 QAIPVTASLYLPSYDYIVCGREDGSIVVT 43 6789**********************986 PP == domain 2 score: 1.1 bits; conditional E-value: 0.36 PEP5_VPS11_N 123 kpfpvsalavsedlsllavGfangsVllirgd 154 +fpv +++ + ++l+vG ++gsV++++ + FUN_000320-T1 166 HAFPVETIKWRALDDFLVVGCSDGSVYVWQME 197 47888999988889999999999999998765 PP == domain 3 score: 6.8 bits; conditional E-value: 0.0066 PEP5_VPS11_N 129 alavsedlsllavGfangsVllirgdlirdrgskqrvvyeseepItglafreeskstvLFvvTtskvlsynl 200 +++ s++ lavG +ng++ l+ r+s+ +++ ++++t l+f+ +++++ + sk+ ++ FUN_000320-T1 978 MVSYSPQSRRLAVGAKNGQIALYDL-----RSSRCQMLPAHSSQVTALSFSPDDRALASYSFGDSKIHFWQT 1044 5667778888999999999999965.....888899999999999999999998888888888888877665 PP >> Beta-prop_RSE1_2nd RSE1/DDB1/CPSF1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.0047 3.1 163 206 .. 170 225 .. 108 252 .. 0.67 2 ? 1.9 0.0 0.23 1.5e+02 161 194 .. 950 1017 .. 850 1060 .. 0.61 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0047 Beta-prop_RSE1_2nd 163 l........seflvvgtwdgtvrifslsd...lngldllssqaLsds.peessprs 206 + +flvvg++dg+v++ ++++ + +++ ++ ++ ++ +ee +p s FUN_000320-T1 170 VetikwralDDFLVVGCSDGSVYVWQMETghlDRCVSGQVALNILSAcDEENKPNS 225 13445555578*****************9877666665544444333644555544 PP == domain 2 score: 1.9 bits; conditional E-value: 0.23 Beta-prop_RSE1_2nd 161 s...........................ql.....seflvvgtwdgtvrifslsd..lngldllssqa 194 + s+ l+vg +g++ +++l + + +l ssq FUN_000320-T1 950 DivvycldqrqlkekgmtelfpglcrfnMVsyspqSRRLAVGAKNGQIALYDLRSsrCQMLPAHSSQV 1017 03334344443444433333333333332244445788999999999999999885533333333333 PP >> PELP1_HEAT PELP1, middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 3.6 2.4e+03 19 44 .. 32 56 .. 19 58 .. 0.85 2 ? 9.5 0.1 0.0022 1.4 14 47 .. 292 325 .. 287 327 .. 0.86 3 ? -2.0 0.0 8.6 5.7e+03 20 33 .. 572 585 .. 564 592 .. 0.72 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 3.6 PELP1_HEAT 19 tCGasegsLqvsafsseaLltaLlsd 44 +CG +gs+ v + + a +t+Ll + FUN_000320-T1 32 VCGREDGSIVVTS-AARAAITQLLQP 56 7********9999.888888999876 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0022 PELP1_HEAT 14 ellvltCGasegsLqvsafsseaLltaLlsdivP 47 ++ + CG ++ +qv f +eaL+ +Ll + P FUN_000320-T1 292 KVMSTKCGDRDPEIQVLLFDTEALICNLLTEEDP 325 556677**********************987655 PP == domain 3 score: -2.0 bits; conditional E-value: 8.6 PELP1_HEAT 20 CGasegsLqvsafs 33 C +++L+vs+f FUN_000320-T1 572 CCLLADILKVSSFK 585 77778888888886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 672 (0.0263065); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 39 (0.00152672); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 39 [number of targets reported over threshold] # CPU time: 0.52u 0.39s 00:00:00.91 Elapsed: 00:00:00.43 # Mc/sec: 10294.25 // Query: FUN_000321-T1 [L=180] Description: FUN_000321 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-10 39.5 1.0 6.3e-08 32.9 1.0 2.3 1 LRR_9 Leucine-rich repeat 3.6e-09 37.1 1.2 0.00029 21.5 0.0 3.1 3 LRR_4 Leucine Rich repeats (2 copies) 9.6e-08 32.1 0.9 0.0073 16.1 0.0 3.0 3 DHU1_N DWD hypersensitive to UV-B 1, N-terminal ------ inclusion threshold ------ 0.04 14.5 2.6 16 6.7 0.1 3.3 3 LRR_1 Leucine Rich Repeat 0.17 12.4 0.0 0.24 11.9 0.0 1.3 1 BARF1_ig2 BARF1 second Ig-like domain 0.23 11.7 7.2 9.3 6.6 6.2 3.2 3 LRR_8 Leucine rich repeat Domain annotation for each model (and alignments): >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.9 1.0 1.5e-11 6.3e-08 54 166 .. 37 156 .. 35 163 .. 0.78 Alignments for each domain: == domain 1 score: 32.9 bits; conditional E-value: 1.5e-11 LRR_9 54 irkldgfPllkrlktlllnnnrilrigegleevlPnleeliltknslqelad.ldPlas.lkkltslsllrnpvt..........nkedyrlyviy 137 i ld+f k+l+tl+l+nn+++ + ++ +l++l + +n++++l+ ++ +a+ +++l ++s+++n + + +dyr yvi FUN_000321-T1 37 ITVLDDF---KKLNTLILDNNKLTSHVN--FPIIESLHTLWVNHNKITNLSSfVETIAKcFPHLRYFSMMNNEAApsyfnggtyyQYKDYRCYVIS 127 5556655...7899*******9975433..3688999*************983466765489*********976533333333335699******* PP LRR_9 138 klkqlrlldfrkvklkeredaeelfrskk 166 +l++l +ld + + +ere+a++++ ++ FUN_000321-T1 128 HLPSLTVLDDHAITEEEREEARKIYGNRR 156 ***********************998776 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.3 0.00012 0.49 12 38 .. 33 58 .. 29 58 .. 0.85 2 ! 21.5 0.0 6.7e-08 0.00029 2 34 .. 67 103 .. 66 107 .. 0.84 3 ? 1.1 0.0 0.17 7.4e+02 20 29 .. 127 136 .. 122 136 .. 0.83 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00012 LRR_4 12 ritdidplskLpnLetLdLsgNnkitd 38 +i di l ++++L tL L +Nnk+t+ FUN_000321-T1 33 KIDDITVLDDFKKLNTLIL-DNNKLTS 58 5788888999*******88.9999985 PP == domain 2 score: 21.5 bits; conditional E-value: 6.7e-08 LRR_4 2 nLetLdLsnNritdidpls....k.LpnLetLdLsgNn 34 +L+tL+ ++N+it+++++ k +p+L++ ++ Nn FUN_000321-T1 67 SLHTLWVNHNKITNLSSFVetiaKcFPHLRYFSM-MNN 103 89***************44456677*********.554 PP == domain 3 score: 1.1 bits; conditional E-value: 0.17 LRR_4 20 skLpnLetLd 29 s+Lp+L++Ld FUN_000321-T1 127 SHLPSLTVLD 136 459****997 PP >> DHU1_N DWD hypersensitive to UV-B 1, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.7 0.1 0.0049 21 134 157 .. 34 57 .. 29 63 .. 0.87 2 ! 8.9 0.0 0.00026 1.1 145 177 .. 67 102 .. 60 113 .. 0.85 3 ! 16.1 0.0 1.7e-06 0.0073 333 368 .. 118 153 .. 112 155 .. 0.92 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.0049 DHU1_N 134 ihklnivgeftqlhtlildknriv 157 i + ++ +f +l tlild+n++ FUN_000321-T1 34 IDDITVLDDFKKLNTLILDNNKLT 57 77889999*************986 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00026 DHU1_N 145 qlhtlildknriv...gfgedcfscmpkltylsmcd 177 lhtl +++n+i f e c+p+l y+sm + FUN_000321-T1 67 SLHTLWVNHNKITnlsSFVETIAKCFPHLRYFSMMN 102 69********9973336899**************86 PP == domain 3 score: 16.1 bits; conditional E-value: 1.7e-06 DHU1_N 333 ekhyrmyminslpklqvldnlairksdrdkaietys 368 k yr y+i lp l vld+ ai + +r++a + y FUN_000321-T1 118 YKDYRCYVISHLPSLTVLDDHAITEEEREEARKIYG 153 589**************************9998885 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.2 0.0059 25 1 14 [. 45 58 .. 45 66 .. 0.79 2 ? 6.7 0.1 0.0038 16 1 16 [. 67 81 .. 67 91 .. 0.76 3 ? -1.5 0.0 2.3 9.6e+03 1 10 [. 94 103 .. 94 105 .. 0.86 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0059 LRR_1 1 nLeeLdLsnNnlsg 14 +L +L L+nN+l++ FUN_000321-T1 45 KLNTLILDNNKLTS 58 599*********63 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0038 LRR_1 1 nLeeLdLsnNnlsgll 16 +L +L++++N+++ l FUN_000321-T1 67 SLHTLWVNHNKITN-L 81 799*********62.2 PP == domain 3 score: -1.5 bits; conditional E-value: 2.3 LRR_1 1 nLeeLdLsnN 10 +L+++++ nN FUN_000321-T1 94 HLRYFSMMNN 103 6999999998 PP >> BARF1_ig2 BARF1 second Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 5.6e-05 0.24 4 94 .. 63 152 .. 60 159 .. 0.81 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 5.6e-05 BARF1_ig2 4 pltlsvhakrsvypdfsvltvrckvnayphphvewlmpegvepaptlangqvlkekdgslsvvvdlslpkpwllpvtcvgkndkeeargvy 94 p+ s+h+ + ++ l+ ++ a ph +++ e ap+ ng++ + v +lp l ++ +++eear +y FUN_000321-T1 63 PIIESLHTLWVNHNKITNLSSFVETIAKCFPHLRYFSMMNNEAAPSYFNGGTYYQYKD-YRCYVISHLPSLTVLDDHAITEEEREEARKIY 152 66667777777777778888778888888999999999999*********99876544.34455679*********************999 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 3.1 0.0025 11 22 60 .. 41 77 .. 33 78 .. 0.68 2 ? 6.6 6.2 0.0022 9.3 2 59 .. 45 103 .. 44 104 .. 0.73 3 ? 0.6 0.0 0.16 6.9e+02 45 55 .. 126 136 .. 124 136 .. 0.65 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0025 LRR_8 22 kglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNr 60 + ++L++L L nN+lt+ f +sL +L +++N+ FUN_000321-T1 41 DDFKKLNTLILDNNKLTSH--VNFPIIESLHTLWVNHNK 77 4578888888888888875..256666666666666666 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0022 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafs.....gLpsLrsLdLsgN 59 +L++L+L++N+lts F ++L +L ++N++t ls +f+ ++p+Lr+ ++ +N FUN_000321-T1 45 KLNTLILDNNKLTS--HVNFPIIESLHTLWVNHNKITNLS--SFVetiakCFPHLRYFSMMNN 103 799********997..55666669***********99998..664222225666666666666 PP == domain 3 score: 0.6 bits; conditional E-value: 0.16 LRR_8 45 fsgLpsLrsLd 55 +s+LpsL+ Ld FUN_000321-T1 126 ISHLPSLTVLD 136 56777777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (180 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 725 (0.0283813); expected 510.9 (0.02) Passed bias filter: 548 (0.0214523); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1812.90 // Query: FUN_000322-T1 [L=182] Description: FUN_000322 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-17 62.2 0.2 1.2e-16 61.2 0.2 1.5 1 FOP_dimer FOP N terminal dimerisation domain 3.7e-05 23.2 0.0 6.4e-05 22.4 0.0 1.4 1 LisH_2 LisH ------ inclusion threshold ------ 0.018 16.0 0.1 0.038 15.0 0.1 1.5 1 Dimer_MINDY4_N MINDY4, N-terminal dimerisation domain 0.088 13.3 0.5 0.18 12.3 0.5 1.5 1 LisH LisH 0.29 11.8 0.5 0.65 10.7 0.5 1.5 1 ARMC9_LisH ARMC9, LIS1 homology motif Domain annotation for each model (and alignments): >> FOP_dimer FOP N terminal dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.2 0.2 2.3e-20 1.2e-16 6 81 .] 48 114 .. 43 114 .. 0.89 Alignments for each domain: == domain 1 score: 61.2 bits; conditional E-value: 2.3e-20 FOP_dimer 6 neNLkkvlstkeGrlvaeLirefLeffeldytlavfspEanlseelddRevlskeLnises.dsaknkPLLlevvkr 81 neN l++eLire+L f++++yt +v+ +E++++ e+ dR++l +eLni ++ +s+ + PLL++++++ FUN_000322-T1 48 NEN----------LLINELIREYLVFNKYKYTESVLLAETGQPMEPMDRKFLIQELNIADEqESSPSMPLLYGILSH 114 444..........49*******************************************9762677899******997 PP >> LisH_2 LisH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.0 1.2e-08 6.4e-05 1 26 [. 53 78 .. 53 80 .. 0.96 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.2e-08 LisH_2 1 lnsLvaEYLasqgYsYTLSVFlPEsG 26 +n L+ EYL ++Y YT SV l E+G FUN_000322-T1 53 INELIREYLVFNKYKYTESVLLAETG 78 699**********************9 PP >> Dimer_MINDY4_N MINDY4, N-terminal dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.1 7.5e-06 0.038 4 50 .. 52 97 .. 49 104 .. 0.90 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 7.5e-06 Dimer_MINDY4_N 4 laaaLVREyLsrkglkkTlktldeElprtessisnrseLikvlhLek 50 l++ L+REyL+ +++k T ++l E+ + + + r+ Li++l++ + FUN_000322-T1 52 LINELIREYLVFNKYKYTESVLLAETGQPMEPMD-RKFLIQELNIAD 97 6788************************988887.999****99975 PP >> LisH LisH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.5 3.5e-05 0.18 2 27 .] 52 77 .. 52 77 .. 0.95 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 3.5e-05 LisH 2 eLNrLIldYLvkeGYeetAeaFekEa 27 ++N LI +YLv + Y+ t + ++ E+ FUN_000322-T1 52 LINELIREYLVFNKYKYTESVLLAET 77 59********************9997 PP >> ARMC9_LisH ARMC9, LIS1 homology motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.5 0.00013 0.65 4 23 .. 53 72 .. 53 76 .. 0.85 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00013 ARMC9_LisH 4 LLgmvkEYLkFaeFeeTvks 23 ++ +++EYL F + T ++ FUN_000322-T1 53 INELIREYLVFNKYKYTESV 72 589*********99888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 402 (0.0157369); expected 510.9 (0.02) Passed bias filter: 372 (0.0145625); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1849.67 // Query: FUN_000323-T1 [L=1817] Description: FUN_000323 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-271 903.1 10.8 1.5e-271 903.1 10.8 2.6 3 Myosin_head Myosin head (motor domain) 4.7e-37 126.8 2.9 4.7e-37 126.8 2.9 3.5 3 DIL DIL domain 2.4e-17 61.5 54.3 3.5e-05 23.7 1.8 7.6 8 IQ IQ calmodulin-binding motif 7.9e-05 22.9 0.6 7.9e-05 22.9 0.6 2.1 2 Myosin_N Myosin N-terminal SH3-like domain 0.0065 17.5 0.1 0.058 14.4 0.0 2.7 3 AAA_16 AAA ATPase domain ------ inclusion threshold ------ 0.01 16.6 0.3 0.075 13.8 0.0 2.6 2 AAA_22 AAA domain 0.024 15.4 1.2 19 6.2 0.0 3.7 4 HTH_17 Helix-turn-helix domain 0.046 13.9 3.8 2 8.6 2.0 3.1 3 AAA_24 AAA domain 0.062 13.3 17.5 2 8.5 2.6 4.7 4 IQ_SCN5A_C SCN5A-like, C-terminal IQ motif 0.072 13.7 0.6 0.79 10.3 0.4 2.7 2 Mating_N Mating-type protein beta 1 0.65 10.7 0.0 0.65 10.7 0.0 3.2 3 NPHP3_N Nephrocystin 3, N-terminal Domain annotation for each model (and alignments): >> Myosin_head Myosin head (motor domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 903.1 10.8 6.3e-275 1.5e-271 2 679 .] 71 735 .. 70 735 .. 0.97 2 ? -2.9 1.6 0.87 2e+03 272 324 .. 982 1037 .. 922 1048 .. 0.57 3 ? -5.9 4.8 7 1.6e+04 486 569 .. 1259 1346 .. 1184 1366 .. 0.48 Alignments for each domain: == domain 1 score: 903.1 bits; conditional E-value: 6.3e-275 Myosin_head 2 edlveLsllneasvlenlkkRyk.kdliYtysglvlvavnPykklkiysedvikaykgkkkeelpPHifaiadeayrsmlqdkenqsilisGEsGA 96 +dl++Ls+l+e++vl nl+ R+ ++ iYty+g+vlva+nPy++l++ys+d+i+ay+g+++ +++PHifa+a++a+r+m +d++nqsi++sGEsGA FUN_000323-T1 71 NDLTTLSYLHEPAVLYNLQVRFLqSNAIYTYCGIVLVAINPYQQLPLYSQDIIAAYSGQSMGDMDPHIFAVAEDAFRAMSRDRQNQSIIVSGESGA 166 79********************73678********************************************************************* PP Myosin_head 97 GKteatKkvlqylasvseskeevekeeveekilqsnPilEafGnAktvrnnnssRFGKyieiefdkkgkiagakietYLLEksRvvkqaeeERnyH 192 GKt+++K+ ++y+asv + ++ +++ve+k+l+snPi+Ea+GnAkt+rn+nssRFGKy+ei+fdk+ +i+ga+++tYLLEksRvv+qa +ERnyH FUN_000323-T1 167 GKTVSAKYAMRYFASVGGASS---ETQVEKKVLASNPIMEAIGNAKTIRNDNSSRFGKYLEISFDKNHQIIGAHMRTYLLEKSRVVFQAVDERNYH 259 ******************999...578********************************************************************* PP Myosin_head 193 iFYqllagaseeekkelkledvkdyaylsqsgeltvdgiddseefketkkaldvlglseeeqkeifrivaailhlGniefkkeakeeqavskdeek 288 iFYql+a + e+k+l+l + +++ yl+q+++ vd +dd e f+e+++a+d+lg+ e++q+ ifri+a+ilh+Gni+++ + +ee+ +s+++ + FUN_000323-T1 260 IFYQLCAACDLPELKDLRLGHQDNFYYLNQGECPYVDDVDDGEGFEEMREAMDLLGIMEDQQQMIFRILAGILHIGNINIQPAGDEESEISDKDVH 355 ***********************************************************************************9999889999999 PP Myosin_head 289 lekaaellgvdaeelekalvkrriktgkevvskalnveqakvardalakaiyerlFdwlvekinkslekkkeekksfiGvLDiaGFEifeknsFEq 384 l++aaellgv+ ++l+k++++r+i t +ev++k+lnv +a++ r+a++k+iy++lF+w+v+ in+sl++++ +++sf+G+LDi+GFE+fe+nsFEq FUN_000323-T1 356 LSIAAELLGVQRNQLKKWMCNRKIVTVQEVLIKPLNVDEANCGREAISKHIYSQLFKWIVQCINNSLSNNA-KQHSFLGILDIYGFETFEVNSFEQ 450 *********************************************************************99.99********************** PP Myosin_head 385 lcinyvnEkLqqlFnelvlklEqeeYvrEgiewefidfgldnqaiidLiekkplGilslLdeecllpkatdetfleklvkefekhakfeksrlkks 480 +ciny+nEkLqq+F ++v+klEqeeYv+E+iew+fi+f +dnq++idLie+k lGil+lLdeec++pk+ d+++++kl+k++ ++++f+k+r +s FUN_000323-T1 451 FCINYANEKLQQQFTQHVFKLEQEEYVKEEIEWSFINF-YDNQPCIDLIESK-LGILDLLDEECKMPKGADRSWVQKLYKNHLNKKHFSKPR--MS 542 **************************************.9***********6.**************************************9..6* PP Myosin_head 481 eakFiikHyAgkveYevegfleKnkDtlnedlvellkkskkkllaelfkeeekeakaeakksekkkkkkkkkkkfktvgskfkeslaeLmktlest 576 e++Fi++H+A++veYev+gf+eKn+Dt+n++++++lk+s+ + + +lf ++e + + +k ++++++k+ +k++++vgs+f+esl++Lm tl++t FUN_000323-T1 543 ETAFIVHHFADNVEYEVKGFVEKNRDTVNKEHLAILKASEYDTVGDLFTDNEA--HLAPRKRSASRSNKNVTKSKRSVGSEFRESLSKLMLTLNNT 636 **************************************************776..45556666666777777789********************* PP Myosin_head 577 nphyvRCikpnekkkakkldeslvleqlrclGvlegirirraGfpnRitfeefvqrYkilakkelkeleklkedakkaveailkkleldkeeykiG 672 phy+RCikpn++k++ +++ ++ ++qlr++Gvle++ri++aG+p+R+ + ef+ rY++l+k e + +++ ++++ ilk+ d +++++G FUN_000323-T1 637 APHYIRCIKPNDRKASFQFNPQRSIQQLRACGVLETVRISAAGYPSRWSYPEFFARYRMLLKFEDIN----RKKPYNTIRVILKRFIKDPDKFQMG 728 *************************************************************998644....47888999***************** PP Myosin_head 673 ktKiFfr 679 ktKiFfr FUN_000323-T1 729 KTKIFFR 735 ******8 PP == domain 2 score: -2.9 bits; conditional E-value: 0.87 Myosin_head 272 fkkeakeeqavskdeeklekaa.....ellgvdae.elekalvkrriktgkevvskaln 324 +++k+++++++ +l+++ el++++ e +ka+++r+i+ + e+vs++l+ FUN_000323-T1 982 RDDSRKQSKTEKE---QLDEINeklkeELMKLKDElAESKAITEREISLRDEIVSQSLE 1037 2222222222222...2333330000033333222023345555555555555555554 PP == domain 3 score: -5.9 bits; conditional E-value: 7 Myosin_head 486 ikHyAgkveYevegfleKnkDtlnedl.vellkkskk...kllaelfkeeek.eakaeakksekkkkkkkkkkkfktvgskfkeslaeL 569 + A+++ +ve+ l+ n D l e lkk+++ + l+el+++e++ ++++++ +ek++ ++ + ++ +++ +f +++++L FUN_000323-T1 1259 MASVAKEI-HNVEEMLKNNPDESAYVLqAESLKKANNvlqNELKELMEKEAElKNANDKLWKEKADLQRGRGTSLSAMDGNFNKAVSQL 1346 33333333.45666666666643322202233333320002233333332222222222222333333333333333333444444444 PP >> DIL DIL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.5 0.3 7e+02 2 23 .. 406 427 .. 405 466 .. 0.86 2 ? -2.2 0.0 2.9 6.6e+03 54 74 .. 813 833 .. 779 861 .. 0.75 3 ! 126.8 2.9 2e-40 4.7e-37 1 105 [] 1649 1752 .. 1649 1752 .. 0.98 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.3 DIL 2 lfsqlfyfinaelfNrlllrkk 23 + sqlf++i + N+l ++ k FUN_000323-T1 406 IYSQLFKWIVQCINNSLSNNAK 427 6899999998888888877766 PP == domain 2 score: -2.2 bits; conditional E-value: 2.9 DIL 54 sarehlepliqalqlLqlkks 74 +r+++ ++++a+ ++q+ + FUN_000323-T1 813 VCRKQFVSIRKAVVIIQCYTR 833 567777788888777777554 PP == domain 3 score: 126.8 bits; conditional E-value: 2e-40 DIL 1 qlfsqlfyfinaelfNrlllrkklcswskGlqirynlskleeWarskglepeksarehlepliqalqlLqlkkstledleeilevcpaLnpaql 94 q+f+qlfy+i+a+++N+lllrk++c+ws+G+qir+nls+le+W+r ++le + ++ e le++iqa+qlLq++k+tled+++i+evc++Ln++q+ FUN_000323-T1 1649 QVFRQLFYYIGANMMNNLLLRKDMCHWSRGMQIRFNLSQLEDWVRLNQLEGS-GIVEALENVIQATQLLQVNKKTLEDVDAICEVCSSLNTLQV 1741 89***********************************************666.99*************************************** PP DIL 95 kklltnYkped 105 +k+l++Y+p++ FUN_000323-T1 1742 QKILSMYTPAN 1752 ********985 PP >> IQ IQ calmodulin-binding motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 9.6 2.2e+04 6 15 .. 233 242 .. 233 243 .. 0.84 2 ? -1.8 0.0 2.4 5.6e+03 7 20 .. 523 536 .. 522 536 .. 0.90 3 ! 8.2 0.1 0.0015 3.5 1 20 [. 751 770 .. 751 771 .. 0.89 4 ! 22.0 2.9 5.3e-08 0.00012 1 19 [. 774 792 .. 774 794 .. 0.92 5 ! 23.7 1.8 1.5e-08 3.5e-05 2 20 .. 800 818 .. 799 819 .. 0.95 6 ! 14.0 1.0 2e-05 0.047 1 18 [. 822 839 .. 822 840 .. 0.95 7 ! 14.8 8.0 1.1e-05 0.026 4 21 .] 850 867 .. 848 867 .. 0.94 8 ! 7.6 1.3 0.0022 5.2 2 21 .] 871 890 .. 870 890 .. 0.91 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 9.6 IQ 6 kIQaawRGyl 15 +I a+ R yl FUN_000323-T1 233 IIGAHMRTYL 242 5789*****9 PP == domain 2 score: -1.8 bits; conditional E-value: 2.4 IQ 7 IQaawRGylaRkry 20 Q+ ++ +l +k++ FUN_000323-T1 523 VQKLYKNHLNKKHF 536 69*******99998 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0015 IQ 1 rkaaikIQaawRGylaRkry 20 r++ i IQ+ +R ++ + y FUN_000323-T1 751 RDSCIMIQKNFRCWREHRLY 770 6899**********999887 PP == domain 4 score: 22.0 bits; conditional E-value: 5.3e-08 IQ 1 rkaaikIQaawRGylaRkr 19 r++ai+IQa+ RGylaR+ FUN_000323-T1 774 RRSAILIQAWLRGYLARRL 792 79***************96 PP == domain 5 score: 23.7 bits; conditional E-value: 1.5e-08 IQ 2 kaaikIQaawRGylaRkry 20 +aai+IQ+++RGy++Rk++ FUN_000323-T1 800 RAAITIQKCYRGYVCRKQF 818 9****************99 PP == domain 6 score: 14.0 bits; conditional E-value: 2e-05 IQ 1 rkaaikIQaawRGylaRk 18 rka+++IQ++ RG+ aR+ FUN_000323-T1 822 RKAVVIIQCYTRGMFARR 839 79***************9 PP == domain 7 score: 14.8 bits; conditional E-value: 1.1e-05 IQ 4 aikIQaawRGylaRkryk 21 a +IQ++wR+y+aRkry+ FUN_000323-T1 850 AKIIQRCWRRYRARKRYR 867 789**************8 PP == domain 8 score: 7.6 bits; conditional E-value: 0.0022 IQ 2 kaaikIQaawRGylaRkryk 21 k +i +Q+++R+++a++++k FUN_000323-T1 871 KNVIYLQSCVRRMRAKRQLK 890 6799*************986 PP >> Myosin_N Myosin N-terminal SH3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.6 3.4e-08 7.9e-05 4 42 .. 11 51 .. 8 53 .. 0.91 2 ? -3.2 0.5 4.6 1.1e+04 21 35 .. 969 985 .. 967 993 .. 0.52 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 3.4e-08 Myosin_N 4 klVWVpDpkegfvkGeikeeegdk..vtVetedGktvtVkk 42 +VW+p+ + ++ Ge++++ g++ +++e+edG ++tV+ FUN_000323-T1 11 ARVWIPHSQVVWIGGELTKDLGENgvLEIELEDGNEITVDV 51 68********************998899999********86 PP == domain 2 score: -3.2 bits; conditional E-value: 4.6 Myosin_N 21 keeegdk..vtVetedG 35 ke + + vtVe +d FUN_000323-T1 969 KELKEELhvVTVERDDS 985 54444332266666443 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.0 2.5e-05 0.058 13 48 .. 143 179 .. 136 215 .. 0.83 2 ? -2.7 0.0 4.5 1e+04 41 128 .. 548 632 .. 546 640 .. 0.58 3 ? -3.7 0.1 9.1 2.1e+04 94 105 .. 1037 1048 .. 1018 1118 .. 0.61 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.5e-05 AAA_16 13 lallervrsgrp.plvlvsGeaGvGKSalvrellral 48 ++++++ ++ r ++++vsGe+G+GK++ ++ ++r FUN_000323-T1 143 EDAFRAMSRDRQnQSIIVSGESGAGKTVSAKYAMRYF 179 5789988888888***************999998654 PP == domain 2 score: -2.7 bits; conditional E-value: 4.5 AAA_16 41 vrellralera.alvlsgkcdelqrglpyaallealtresllrqllaeseaallaawraalleelaavpalegeeaerllealsrllal 128 v+++++ +e + ++++ + d + a+l+a +++ + +l +++ea l+++ r a ++ + v + ++ ++e ls+l+ FUN_000323-T1 548 VHHFADNVEYEvKGFVEKNRDTV--NKEHLAILKAS-EYDTVGDLFTDNEAHLAPRKRSASRSNKN-VTKSKRSVGSEFRESLSKLMLT 632 56666666666544555555555..33345667777.66999999999888676666665444333.3333444447788887777744 PP == domain 3 score: -3.7 bits; conditional E-value: 9.1 AAA_16 94 aawraalleela 105 +a r++ll+e++ FUN_000323-T1 1037 EAQREQLLAEFE 1048 333333333333 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 3.2e-05 0.075 3 32 .. 153 182 .. 151 276 .. 0.72 2 ? -2.1 0.3 2.7 6.2e+03 46 82 .. 991 1039 .. 967 1072 .. 0.55 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 3.2e-05 AAA_22 3 stagilvltGesGtGKTtllrrlleqldee 32 ++ +++++ GesG+GKT+++++ ++ + ++ FUN_000323-T1 153 RQNQSIIVSGESGAGKTVSAKYAMRYFASV 182 47899***************9988876544 PP == domain 2 score: -2.1 bits; conditional E-value: 2.7 AAA_22 46 spkdllrellralglelek...........elskeell.aalqealkal 82 + k+ l e+ ++l++el k ++++ l+ + + + l+a+ FUN_000323-T1 991 TEKEQLDEINEKLKEELMKlkdelaeskaiTEREISLRdEIVSQSLEAQ 1039 5555566666666666666555566666664444444433333333333 PP >> HTH_17 Helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.0081 19 7 28 .. 359 380 .. 359 393 .. 0.88 2 ? -3.7 0.1 9.5 2.2e+04 16 31 .. 878 893 .. 877 897 .. 0.78 3 ? 5.4 0.0 0.014 32 20 48 .. 1665 1693 .. 1658 1694 .. 0.80 4 ? -2.3 0.0 3.5 8.2e+03 6 18 .. 1711 1723 .. 1709 1725 .. 0.86 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0081 HTH_17 7 aAelLgvsrrTvyrlirsGelp 28 aAelLgv r+ + +++ ++++ FUN_000323-T1 359 AAELLGVQRNQLKKWMCNRKIV 380 8***************999995 PP == domain 2 score: -3.7 bits; conditional E-value: 9.5 HTH_17 16 rTvyrlirsGelpaak 31 + v+r++ +++l+ k FUN_000323-T1 878 SCVRRMRAKRQLKQLK 893 5699****99997655 PP == domain 3 score: 5.4 bits; conditional E-value: 0.014 HTH_17 20 rlirsGelpaak.iGrrwriprsdLeewle 48 +l +++ ++ +G ++r++ s Le+w++ FUN_000323-T1 1665 NLLLRKDM-CHWsRGMQIRFNLSQLEDWVR 1693 56667777.776699*************86 PP == domain 4 score: -2.3 bits; conditional E-value: 3.5 HTH_17 6 EaAelLgvsrrTv 18 +a +lL+v ++T+ FUN_000323-T1 1711 QATQLLQVNKKTL 1723 7889********8 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.033 77 2 22 .. 155 175 .. 154 181 .. 0.87 2 ? 8.6 2.0 0.00086 2 90 168 .. 939 1017 .. 924 1046 .. 0.80 3 ? -3.2 0.0 3.4 7.8e+03 112 167 .. 1467 1523 .. 1465 1545 .. 0.69 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.033 AAA_24 2 klkvliyGpsgiGKTtlaksl 22 ++++++ G+sg GKT ak + FUN_000323-T1 155 NQSIIVSGESGAGKTVSAKYA 175 7899************99987 PP == domain 2 score: 8.6 bits; conditional E-value: 0.00086 AAA_24 90 kaeki.edkgdgkG.ygelkeefrrlldalqelgk..nvvfiahekerkdedeegekytryepklgektakeleeivDlvlrl 168 + +k+ e + ++kG + ++++++ +l ++el++ +vv + + + rk+ ++e+e+ +++ek+++el ++ D++++ FUN_000323-T1 939 VTRKElEHAKQWKGqFELAQTKILQLELEIKELKEelHVVTVERDDSRKQSKTEKEQ----LDEINEKLKEELMKLKDELAES 1017 444445667889***************************************998885....5566777777777777777665 PP == domain 3 score: -3.2 bits; conditional E-value: 3.4 AAA_24 112 rlldalqelgknvvfiahekerkdedeege.kytryepklgektakeleeivDlvlr 167 ++ da+ l+ +++f +++ + + d++++ + + ++ k+ k+ +e +D++++ FUN_000323-T1 1467 SMADAIPGLPAHILFMCIRHADHVNDDRRMqSLLTNSINSIRKVVKKNPENLDILAF 1523 567888899999999999999999999888544444444444445555666666655 PP >> IQ_SCN5A_C SCN5A-like, C-terminal IQ motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.029 68 13 23 .. 755 765 .. 752 771 .. 0.81 2 ? 0.6 0.1 0.25 5.9e+02 10 31 .. 775 796 .. 774 799 .. 0.82 3 ? 8.0 1.2 0.0012 2.8 7 25 .. 797 815 .. 794 821 .. 0.87 4 ? 8.5 2.6 0.00086 2 12 27 .. 850 865 .. 841 872 .. 0.85 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.029 IQ_SCN5A_C 13 avIQkAFRkYl 23 + IQk+FR+ + FUN_000323-T1 755 IMIQKNFRCWR 765 57******986 PP == domain 2 score: 0.6 bits; conditional E-value: 0.25 IQ_SCN5A_C 10 rcAavIQkAFRkYlmkvtkkkl 31 r+A++IQ R Yl ++ +k+l FUN_000323-T1 775 RSAILIQAWLRGYLARRLAKDL 796 89*****88899*988877765 PP == domain 3 score: 8.0 bits; conditional E-value: 0.0012 IQ_SCN5A_C 7 eEErcAavIQkAFRkYlmk 25 +E r+A+ IQk +R Y + FUN_000323-T1 797 REKRAAITIQKCYRGYVCR 815 699*************765 PP == domain 4 score: 8.5 bits; conditional E-value: 0.00086 IQ_SCN5A_C 12 AavIQkAFRkYlmkvt 27 A +IQ+ +R+Y+ + + FUN_000323-T1 850 AKIIQRCWRRYRARKR 865 88*********87655 PP >> Mating_N Mating-type protein beta 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.4 0.00034 0.79 10 57 .. 1028 1075 .. 1021 1083 .. 0.91 2 ? -0.5 0.0 0.84 2e+03 42 59 .. 1373 1390 .. 1338 1396 .. 0.79 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00034 Mating_N 10 sDedvrqtLdalrkdFfssLrgdsealstFlsawskfdellqschdsL 57 +De+v+q+L+a r+++++ +++ ++ ++ l+ +++++++ q+++d+ FUN_000323-T1 1028 RDEIVSQSLEAQREQLLAEFESERSNHQRVLRDYDRLEQRYQNLQDEM 1075 49**********************99*****************99876 PP == domain 2 score: -0.5 bits; conditional E-value: 0.84 Mating_N 42 awskfdellqschdsLse 59 a + f++++qsc+ +L++ FUN_000323-T1 1373 AVAPFRSRIQSCKGDLEQ 1390 667899999999999987 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.00028 0.65 10 48 .. 144 181 .. 140 192 .. 0.80 2 ? -2.7 0.8 3.6 8.4e+03 78 118 .. 963 1005 .. 954 1043 .. 0.59 3 ? -3.2 0.3 5.1 1.2e+04 69 113 .. 1210 1253 .. 1200 1267 .. 0.46 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00028 NPHP3_N 10 eefqeWldspsdssllwlsGkpGsGKsvlastvidhlqa 48 ++f++ +++ +++ + +sG+ G+GK+v a++ ++++ + FUN_000323-T1 144 DAFRAMSRDR-QNQSIIVSGESGAGKTVSAKYAMRYFAS 181 6777777664.677889***************9998765 PP == domain 2 score: -2.7 bits; conditional E-value: 3.6 NPHP3_N 78 qlasqlpelreellekl..aedlgldekdlrelweklletlll 118 ql + +el+eel+ ++d+++++k+ +e+++++ e+l + FUN_000323-T1 963 QLELEIKELKEELHVVTveRDDSRKQSKTEKEQLDEINEKLKE 1005 5555556666655433211333444444445555555444432 PP == domain 3 score: -3.2 bits; conditional E-value: 5.1 NPHP3_N 69 ssllrsllhqlasqlpelreelleklaedlgldekdlrelwekll 113 +llr ll q +++ + + ekl+e + d+k +e ++l FUN_000323-T1 1210 LELLRKLLSQRNVDKEAEWDMINEKLKEM-SDDRKRVDEEKKQLR 1253 45666666666544444334444443332.223333333333343 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1817 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2857 (0.111842); expected 510.9 (0.02) Passed bias filter: 617 (0.0241535); expected 510.9 (0.02) Passed Vit filter: 105 (0.00411039); expected 25.5 (0.001) Passed Fwd filter: 34 (0.00133098); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.72u 0.42s 00:00:01.13 Elapsed: 00:00:00.45 # Mc/sec: 16335.23 // Query: FUN_000323-T2 [L=1420] Description: FUN_000323 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-272 903.9 10.8 8.4e-272 903.9 10.8 2.6 3 Myosin_head Myosin head (motor domain) 3e-18 64.3 53.9 2.7e-05 24.1 1.8 7.7 8 IQ IQ calmodulin-binding motif 6e-05 23.2 0.6 6e-05 23.2 0.6 2.1 2 Myosin_N Myosin N-terminal SH3-like domain 0.0038 18.3 0.2 0.044 14.8 0.0 2.9 3 AAA_16 AAA ATPase domain 0.0063 17.3 0.4 0.056 14.2 0.0 2.8 2 AAA_22 AAA domain ------ inclusion threshold ------ 0.022 14.8 17.6 1.5 8.8 2.6 4.9 4 IQ_SCN5A_C SCN5A-like, C-terminal IQ motif 0.042 14.4 0.6 0.6 10.7 0.4 2.8 2 Mating_N Mating-type protein beta 1 0.053 13.7 4.2 1.5 9.0 2.0 2.7 2 AAA_24 AAA domain 0.072 13.8 0.4 0.072 13.8 0.4 7.9 7 Cnn_1N Centrosomin N-terminal motif 1 0.49 11.0 0.0 0.49 11.0 0.0 3.4 3 NPHP3_N Nephrocystin 3, N-terminal Domain annotation for each model (and alignments): >> Myosin_head Myosin head (motor domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 903.9 10.8 3.3e-275 8.4e-272 2 679 .] 71 735 .. 70 735 .. 0.97 2 ? -2.3 1.5 0.53 1.4e+03 272 324 .. 982 1037 .. 914 1050 .. 0.59 3 ? -5.1 4.1 3.7 9.6e+03 489 571 .. 1262 1348 .. 1211 1366 .. 0.46 Alignments for each domain: == domain 1 score: 903.9 bits; conditional E-value: 3.3e-275 Myosin_head 2 edlveLsllneasvlenlkkRyk.kdliYtysglvlvavnPykklkiysedvikaykgkkkeelpPHifaiadeayrsmlqdkenqsilisGEsGA 96 +dl++Ls+l+e++vl nl+ R+ ++ iYty+g+vlva+nPy++l++ys+d+i+ay+g+++ +++PHifa+a++a+r+m +d++nqsi++sGEsGA FUN_000323-T2 71 NDLTTLSYLHEPAVLYNLQVRFLqSNAIYTYCGIVLVAINPYQQLPLYSQDIIAAYSGQSMGDMDPHIFAVAEDAFRAMSRDRQNQSIIVSGESGA 166 79********************73678********************************************************************* PP Myosin_head 97 GKteatKkvlqylasvseskeevekeeveekilqsnPilEafGnAktvrnnnssRFGKyieiefdkkgkiagakietYLLEksRvvkqaeeERnyH 192 GKt+++K+ ++y+asv + ++ +++ve+k+l+snPi+Ea+GnAkt+rn+nssRFGKy+ei+fdk+ +i+ga+++tYLLEksRvv+qa +ERnyH FUN_000323-T2 167 GKTVSAKYAMRYFASVGGASS---ETQVEKKVLASNPIMEAIGNAKTIRNDNSSRFGKYLEISFDKNHQIIGAHMRTYLLEKSRVVFQAVDERNYH 259 ******************999...578********************************************************************* PP Myosin_head 193 iFYqllagaseeekkelkledvkdyaylsqsgeltvdgiddseefketkkaldvlglseeeqkeifrivaailhlGniefkkeakeeqavskdeek 288 iFYql+a + e+k+l+l + +++ yl+q+++ vd +dd e f+e+++a+d+lg+ e++q+ ifri+a+ilh+Gni+++ + +ee+ +s+++ + FUN_000323-T2 260 IFYQLCAACDLPELKDLRLGHQDNFYYLNQGECPYVDDVDDGEGFEEMREAMDLLGIMEDQQQMIFRILAGILHIGNINIQPAGDEESEISDKDVH 355 ***********************************************************************************9999889999999 PP Myosin_head 289 lekaaellgvdaeelekalvkrriktgkevvskalnveqakvardalakaiyerlFdwlvekinkslekkkeekksfiGvLDiaGFEifeknsFEq 384 l++aaellgv+ ++l+k++++r+i t +ev++k+lnv +a++ r+a++k+iy++lF+w+v+ in+sl++++ +++sf+G+LDi+GFE+fe+nsFEq FUN_000323-T2 356 LSIAAELLGVQRNQLKKWMCNRKIVTVQEVLIKPLNVDEANCGREAISKHIYSQLFKWIVQCINNSLSNNA-KQHSFLGILDIYGFETFEVNSFEQ 450 *********************************************************************99.99********************** PP Myosin_head 385 lcinyvnEkLqqlFnelvlklEqeeYvrEgiewefidfgldnqaiidLiekkplGilslLdeecllpkatdetfleklvkefekhakfeksrlkks 480 +ciny+nEkLqq+F ++v+klEqeeYv+E+iew+fi+f +dnq++idLie+k lGil+lLdeec++pk+ d+++++kl+k++ ++++f+k+r +s FUN_000323-T2 451 FCINYANEKLQQQFTQHVFKLEQEEYVKEEIEWSFINF-YDNQPCIDLIESK-LGILDLLDEECKMPKGADRSWVQKLYKNHLNKKHFSKPR--MS 542 **************************************.9***********6.**************************************9..6* PP Myosin_head 481 eakFiikHyAgkveYevegfleKnkDtlnedlvellkkskkkllaelfkeeekeakaeakksekkkkkkkkkkkfktvgskfkeslaeLmktlest 576 e++Fi++H+A++veYev+gf+eKn+Dt+n++++++lk+s+ + + +lf ++e + + +k ++++++k+ +k++++vgs+f+esl++Lm tl++t FUN_000323-T2 543 ETAFIVHHFADNVEYEVKGFVEKNRDTVNKEHLAILKASEYDTVGDLFTDNEA--HLAPRKRSASRSNKNVTKSKRSVGSEFRESLSKLMLTLNNT 636 **************************************************776..45556666666777777789********************* PP Myosin_head 577 nphyvRCikpnekkkakkldeslvleqlrclGvlegirirraGfpnRitfeefvqrYkilakkelkeleklkedakkaveailkkleldkeeykiG 672 phy+RCikpn++k++ +++ ++ ++qlr++Gvle++ri++aG+p+R+ + ef+ rY++l+k e + +++ ++++ ilk+ d +++++G FUN_000323-T2 637 APHYIRCIKPNDRKASFQFNPQRSIQQLRACGVLETVRISAAGYPSRWSYPEFFARYRMLLKFEDIN----RKKPYNTIRVILKRFIKDPDKFQMG 728 *************************************************************998644....47888999***************** PP Myosin_head 673 ktKiFfr 679 ktKiFfr FUN_000323-T2 729 KTKIFFR 735 ******8 PP == domain 2 score: -2.3 bits; conditional E-value: 0.53 Myosin_head 272 fkkeakeeqavskdeeklekaa.....ellgvdae.elekalvkrriktgkevvskaln 324 +++k+++++++ +l+++ el++++ e +ka+++r+i+ + e+vs++l+ FUN_000323-T2 982 RDDSRKQSKTEKE---QLDEINeklkeELMKLKDElAESKAITEREISLRDEIVSQSLE 1037 2222222222222...2333330000033333222023345555555555555555555 PP == domain 3 score: -5.1 bits; conditional E-value: 3.7 Myosin_head 489 yAgkveYevegfleKnkDtlnedl.vellkkskk...kllaelfkeeek.eakaeakksekkkkkkkkkkkfktvgskfkeslaeLmk 571 A+++ +ve+ l+ n D l e lkk+++ + l+el+++e++ ++++++ +ek++ ++ + ++ +++ +f +++++L++ FUN_000323-T2 1262 VAKEI-HNVEEMLKNNPDESAYVLqAESLKKANNvlqNELKELMEKEAElKNANDKLWKEKADLQRGRGTSLSAMDGNFNKAVSQLVT 1348 44443.4667777777665333220233333333000333333333332222222222333333333444444444445555444443 PP >> IQ IQ calmodulin-binding motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 6.6 1.7e+04 6 15 .. 233 242 .. 233 243 .. 0.84 2 ? -1.1 0.0 1.3 3.4e+03 7 20 .. 523 536 .. 522 537 .. 0.91 3 ! 8.5 0.1 0.001 2.6 1 20 [. 751 770 .. 751 771 .. 0.89 4 ! 22.4 2.9 3.7e-08 9.4e-05 1 19 [. 774 792 .. 774 794 .. 0.92 5 ! 24.1 1.8 1e-08 2.7e-05 2 20 .. 800 818 .. 799 819 .. 0.95 6 ! 14.3 1.0 1.4e-05 0.036 1 18 [. 822 839 .. 822 840 .. 0.95 7 ! 15.2 8.0 7.6e-06 0.019 4 21 .] 850 867 .. 848 867 .. 0.94 8 ! 8.0 1.3 0.0015 3.9 2 21 .] 871 890 .. 870 890 .. 0.91 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 6.6 IQ 6 kIQaawRGyl 15 +I a+ R yl FUN_000323-T2 233 IIGAHMRTYL 242 5789*****9 PP == domain 2 score: -1.1 bits; conditional E-value: 1.3 IQ 7 IQaawRGylaRkry 20 Q+ ++ +l +k++ FUN_000323-T2 523 VQKLYKNHLNKKHF 536 69********9998 PP == domain 3 score: 8.5 bits; conditional E-value: 0.001 IQ 1 rkaaikIQaawRGylaRkry 20 r++ i IQ+ +R ++ + y FUN_000323-T2 751 RDSCIMIQKNFRCWREHRLY 770 6899**********999887 PP == domain 4 score: 22.4 bits; conditional E-value: 3.7e-08 IQ 1 rkaaikIQaawRGylaRkr 19 r++ai+IQa+ RGylaR+ FUN_000323-T2 774 RRSAILIQAWLRGYLARRL 792 79***************96 PP == domain 5 score: 24.1 bits; conditional E-value: 1e-08 IQ 2 kaaikIQaawRGylaRkry 20 +aai+IQ+++RGy++Rk++ FUN_000323-T2 800 RAAITIQKCYRGYVCRKQF 818 9****************99 PP == domain 6 score: 14.3 bits; conditional E-value: 1.4e-05 IQ 1 rkaaikIQaawRGylaRk 18 rka+++IQ++ RG+ aR+ FUN_000323-T2 822 RKAVVIIQCYTRGMFARR 839 79***************9 PP == domain 7 score: 15.2 bits; conditional E-value: 7.6e-06 IQ 4 aikIQaawRGylaRkryk 21 a +IQ++wR+y+aRkry+ FUN_000323-T2 850 AKIIQRCWRRYRARKRYR 867 789**************8 PP == domain 8 score: 8.0 bits; conditional E-value: 0.0015 IQ 2 kaaikIQaawRGylaRkryk 21 k +i +Q+++R+++a++++k FUN_000323-T2 871 KNVIYLQSCVRRMRAKRQLK 890 6799*************986 PP >> Myosin_N Myosin N-terminal SH3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.6 2.3e-08 6e-05 4 42 .. 11 51 .. 8 53 .. 0.91 2 ? -2.8 0.6 3.3 8.5e+03 20 35 .. 968 985 .. 967 994 .. 0.52 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 2.3e-08 Myosin_N 4 klVWVpDpkegfvkGeikeeegdk..vtVetedGktvtVkk 42 +VW+p+ + ++ Ge++++ g++ +++e+edG ++tV+ FUN_000323-T2 11 ARVWIPHSQVVWIGGELTKDLGENgvLEIELEDGNEITVDV 51 68********************998899999********86 PP == domain 2 score: -2.8 bits; conditional E-value: 3.3 Myosin_N 20 ikeeegdk..vtVetedG 35 ike + + vtVe +d FUN_000323-T2 968 IKELKEELhvVTVERDDS 985 554444332266666443 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 1.7e-05 0.044 13 48 .. 143 179 .. 136 215 .. 0.83 2 ? -2.0 0.0 2.6 6.5e+03 41 130 .. 548 634 .. 546 641 .. 0.59 3 ? -2.9 0.1 4.7 1.2e+04 94 105 .. 1037 1048 .. 1005 1127 .. 0.61 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.7e-05 AAA_16 13 lallervrsgrp.plvlvsGeaGvGKSalvrellral 48 ++++++ ++ r ++++vsGe+G+GK++ ++ ++r FUN_000323-T2 143 EDAFRAMSRDRQnQSIIVSGESGAGKTVSAKYAMRYF 179 5789988888888***************999998654 PP == domain 2 score: -2.0 bits; conditional E-value: 2.6 AAA_16 41 vrellralera.alvlsgkcdelqrglpyaallealtresllrqllaeseaallaawraalleelaavpalegeeaerllealsrllalaa 130 v+++++ +e + ++++ + d + a+l+a +++ + +l +++ea l+++ r a ++ + v + ++ ++e ls+l+ + FUN_000323-T2 548 VHHFADNVEYEvKGFVEKNRDTV--NKEHLAILKAS-EYDTVGDLFTDNEAHLAPRKRSASRSNKN-VTKSKRSVGSEFRESLSKLMLTLN 634 56666666666544555555555..33345667777.67999999999888776666665444333.444444444888888888874444 PP == domain 3 score: -2.9 bits; conditional E-value: 4.7 AAA_16 94 aawraalleela 105 +a r++ll+e++ FUN_000323-T2 1037 EAQREQLLAEFE 1048 333333333333 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 2.2e-05 0.056 3 32 .. 153 182 .. 151 276 .. 0.72 2 ? -1.6 0.3 1.7 4.3e+03 46 82 .. 991 1039 .. 966 1073 .. 0.55 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 2.2e-05 AAA_22 3 stagilvltGesGtGKTtllrrlleqldee 32 ++ +++++ GesG+GKT+++++ ++ + ++ FUN_000323-T2 153 RQNQSIIVSGESGAGKTVSAKYAMRYFASV 182 47899***************9988876544 PP == domain 2 score: -1.6 bits; conditional E-value: 1.7 AAA_22 46 spkdllrellralglelek...........elskeell.aalqealkal 82 + k+ l e+ ++l++el k ++++ l+ + + + l+a+ FUN_000323-T2 991 TEKEQLDEINEKLKEELMKlkdelaeskaiTEREISLRdEIVSQSLEAQ 1039 5555566666666666666555566666664444444423333333322 PP >> IQ_SCN5A_C SCN5A-like, C-terminal IQ motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.02 52 13 23 .. 755 765 .. 752 771 .. 0.81 2 ? 0.9 0.1 0.18 4.5e+02 10 31 .. 775 796 .. 774 799 .. 0.82 3 ? 8.3 1.2 0.00087 2.2 7 25 .. 797 815 .. 794 820 .. 0.87 4 ? 8.8 2.6 0.0006 1.5 12 27 .. 850 865 .. 841 872 .. 0.85 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.02 IQ_SCN5A_C 13 avIQkAFRkYl 23 + IQk+FR+ + FUN_000323-T2 755 IMIQKNFRCWR 765 57******986 PP == domain 2 score: 0.9 bits; conditional E-value: 0.18 IQ_SCN5A_C 10 rcAavIQkAFRkYlmkvtkkkl 31 r+A++IQ R Yl ++ +k+l FUN_000323-T2 775 RSAILIQAWLRGYLARRLAKDL 796 89*****88899*988877765 PP == domain 3 score: 8.3 bits; conditional E-value: 0.00087 IQ_SCN5A_C 7 eEErcAavIQkAFRkYlmk 25 +E r+A+ IQk +R Y + FUN_000323-T2 797 REKRAAITIQKCYRGYVCR 815 699*************765 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0006 IQ_SCN5A_C 12 AavIQkAFRkYlmkvt 27 A +IQ+ +R+Y+ + + FUN_000323-T2 850 AKIIQRCWRRYRARKR 865 88*********87655 PP >> Mating_N Mating-type protein beta 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.4 0.00023 0.6 10 57 .. 1028 1075 .. 1021 1083 .. 0.91 2 ? -0.2 0.0 0.58 1.5e+03 42 59 .. 1373 1390 .. 1338 1396 .. 0.79 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00023 Mating_N 10 sDedvrqtLdalrkdFfssLrgdsealstFlsawskfdellqschdsL 57 +De+v+q+L+a r+++++ +++ ++ ++ l+ +++++++ q+++d+ FUN_000323-T2 1028 RDEIVSQSLEAQREQLLAEFESERSNHQRVLRDYDRLEQRYQNLQDEM 1075 49**********************99*****************99876 PP == domain 2 score: -0.2 bits; conditional E-value: 0.58 Mating_N 42 awskfdellqschdsLse 59 a + f++++qsc+ +L++ FUN_000323-T2 1373 AVAPFRSRIQSCKGDLEQ 1390 667899999999999987 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.023 59 2 22 .. 155 175 .. 154 181 .. 0.87 2 ? 9.0 2.0 0.00057 1.5 89 168 .. 938 1017 .. 923 1047 .. 0.80 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.023 AAA_24 2 klkvliyGpsgiGKTtlaksl 22 ++++++ G+sg GKT ak + FUN_000323-T2 155 NQSIIVSGESGAGKTVSAKYA 175 7899************99987 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00057 AAA_24 89 skaeki.edkgdgkG.ygelkeefrrlldalqelgk..nvvfiahekerkdedeegekytryepklgektakeleeivDlvlrl 168 ++ +k+ e + ++kG + ++++++ +l ++el++ +vv + + + rk+ ++e+e+ +++ek+++el ++ D++++ FUN_000323-T2 938 EVTRKElEHAKQWKGqFELAQTKILQLELEIKELKEelHVVTVERDDSRKQSKTEKEQ----LDEINEKLKEELMKLKDELAES 1017 4444445667889***************************************998885....5567777777777777777665 PP >> Cnn_1N Centrosomin N-terminal motif 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 5.0 0.28 7.1e+02 13 58 .. 903 947 .. 892 961 .. 0.77 2 ? -1.3 11.4 1.4 3.6e+03 19 69 .. 964 1017 .. 957 1024 .. 0.65 3 ? -1.2 0.7 1.3 3.4e+03 30 73 .. 1032 1075 .. 1022 1076 .. 0.71 4 ? 4.4 0.1 0.023 59 18 46 .. 1139 1167 .. 1123 1172 .. 0.90 5 ? 6.7 7.6 0.0044 11 27 70 .. 1180 1221 .. 1173 1225 .. 0.83 6 ? -3.7 12.7 7.7 2e+04 2 67 .. 1235 1315 .. 1234 1326 .. 0.69 7 ? 13.8 0.4 2.8e-05 0.072 32 64 .. 1337 1369 .. 1330 1370 .. 0.87 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.28 Cnn_1N 13 kkENFnLKLkihfleerleklapeqieellkenvelkveleslqke 58 kk N ++ ki +l++rl++ + ++e++ +l+v++++l++ FUN_000323-T2 903 KKLNIGMENKIIHLQQRLDQQVK-EKEQAQVAVRQLEVTRKELEHA 947 66677888899*******99999.6666666678888888888765 PP == domain 2 score: -1.3 bits; conditional E-value: 1.4 Cnn_1N 19 LKLkihfleerleklap...eqieellkenvelkveleslqkelkklkkllkea 69 L L+i+ l+e+l+ + ++ ++ e +l +e+l+ el klk++l+e+ FUN_000323-T2 964 LELEIKELKEELHVVTVerdDSRKQSKTEKEQLDEINEKLKEELMKLKDELAES 1017 667888888888776665555555555666666666666666666666666654 PP == domain 3 score: -1.2 bits; conditional E-value: 1.3 Cnn_1N 30 leklapeqieellkenvelkveleslqkelkklkkllkeaekai 73 +++ + q e+ll e + + + ++ ++l+++ +++++++ FUN_000323-T2 1032 VSQSLEAQREQLLAEFESERSNHQRVLRDYDRLEQRYQNLQDEM 1075 55666678888888877777788888888888888888777766 PP == domain 4 score: 4.4 bits; conditional E-value: 0.023 Cnn_1N 18 nLKLkihfleerleklapeqieellkenv 46 ++K++i le++l + + +q+e++ k nv FUN_000323-T2 1139 GMKIRIRELEDKLLEYERSQSEDVPKINV 1167 68*********************999888 PP == domain 5 score: 6.7 bits; conditional E-value: 0.0044 Cnn_1N 27 eerleklapeqieellkenvelkveleslqkelkklkkllkeae 70 e++++ l++ +e+l+ke el++e+++++ el+ l+kll + + FUN_000323-T2 1180 EKYQNALKE--KESLEKEKGELETERKKMKSELELLRKLLSQRN 1221 445555555..9****************************9865 PP == domain 6 score: -3.7 bits; conditional E-value: 7.7 Cnn_1N 2 LrEqeeqidkLkkENFnLKLki..........hfleerleklap.....eqieellkenvelkveleslqkelkklkkllk 67 L+E+++ ++++ E +L+L++ h ee l+++++ q e+l k n l+ el++l + ++lk+ FUN_000323-T2 1235 LKEMSDDRKRVDEEKKQLRLELidmasvakeiHNVEEMLKNNPDesayvLQAESLKKANNVLQNELKELMEKEAELKNAND 1315 789999999999999999999988888888889999999888885555555555555555555555555554444444444 PP == domain 7 score: 13.8 bits; conditional E-value: 2.8e-05 Cnn_1N 32 klapeqieellkenvelkveleslqkelkklkk 64 + ++ + +l+ envelk ++e+l+ e++++k+ FUN_000323-T2 1337 GNFNKAVSQLVTENVELKEQVEKLEAEVEEYKR 1369 555677889**********************96 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00019 0.49 10 48 .. 144 181 .. 140 192 .. 0.80 2 ? -2.3 0.8 2.4 6.1e+03 78 118 .. 963 1005 .. 953 1054 .. 0.61 3 ? -2.5 0.3 2.9 7.3e+03 69 117 .. 1210 1257 .. 1200 1269 .. 0.47 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00019 NPHP3_N 10 eefqeWldspsdssllwlsGkpGsGKsvlastvidhlqa 48 ++f++ +++ +++ + +sG+ G+GK+v a++ ++++ + FUN_000323-T2 144 DAFRAMSRDR-QNQSIIVSGESGAGKTVSAKYAMRYFAS 181 6777777664.677889***************9998765 PP == domain 2 score: -2.3 bits; conditional E-value: 2.4 NPHP3_N 78 qlasqlpelreellekl..aedlgldekdlrelweklletlll 118 ql + +el+eel+ ++d+++++k+ +e+++++ e+l + FUN_000323-T2 963 QLELEIKELKEELHVVTveRDDSRKQSKTEKEQLDEINEKLKE 1005 5555555666555433201333344444444455544444432 PP == domain 3 score: -2.5 bits; conditional E-value: 2.9 NPHP3_N 69 ssllrsllhqlasqlpelreelleklaedlgldekdlrelweklletll 117 +llr ll q +++ + + ekl+e + d+k +e ++l +l+ FUN_000323-T2 1210 LELLRKLLSQRNVDKEAEWDMINEKLKEM-SDDRKRVDEEKKQLRLELI 1257 45677777776544444444444444332.2333333344444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1420 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2988 (0.11697); expected 510.9 (0.02) Passed bias filter: 600 (0.023488); expected 510.9 (0.02) Passed Vit filter: 115 (0.00450186); expected 25.5 (0.001) Passed Fwd filter: 37 (0.00144842); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.70u 0.42s 00:00:01.11 Elapsed: 00:00:00.55 # Mc/sec: 10479.85 // Query: FUN_000323-T3 [L=1640] Description: FUN_000323 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-271 903.4 10.8 1.2e-271 903.4 10.8 2.6 3 Myosin_head Myosin head (motor domain) 5.4e-17 60.4 57.0 3.1e-05 23.8 1.8 7.9 9 IQ IQ calmodulin-binding motif 7e-05 23.0 0.6 7e-05 23.0 0.6 2.2 2 Myosin_N Myosin N-terminal SH3-like domain 0.0054 17.7 0.1 0.052 14.5 0.0 2.8 3 AAA_16 AAA ATPase domain 0.0088 16.9 0.3 0.066 14.0 0.0 2.7 2 AAA_22 AAA domain ------ inclusion threshold ------ 0.042 14.0 4.0 2 8.6 2.2 3.0 3 AAA_24 AAA domain 0.042 13.8 17.6 1.8 8.6 2.6 4.8 4 IQ_SCN5A_C SCN5A-like, C-terminal IQ motif 0.059 13.9 0.6 0.7 10.5 0.4 2.7 2 Mating_N Mating-type protein beta 1 0.58 10.8 0.0 0.58 10.8 0.0 3.3 3 NPHP3_N Nephrocystin 3, N-terminal Domain annotation for each model (and alignments): >> Myosin_head Myosin head (motor domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 903.4 10.8 4.2e-275 1.2e-271 2 679 .] 71 735 .. 70 735 .. 0.97 2 ? -2.7 1.6 0.63 1.8e+03 272 324 .. 982 1037 .. 917 1049 .. 0.58 3 ? -5.9 5.0 5.5 1.6e+04 486 569 .. 1259 1346 .. 1183 1366 .. 0.48 Alignments for each domain: == domain 1 score: 903.4 bits; conditional E-value: 4.2e-275 Myosin_head 2 edlveLsllneasvlenlkkRyk.kdliYtysglvlvavnPykklkiysedvikaykgkkkeelpPHifaiadeayrsmlqdkenqsilisGEsGA 96 +dl++Ls+l+e++vl nl+ R+ ++ iYty+g+vlva+nPy++l++ys+d+i+ay+g+++ +++PHifa+a++a+r+m +d++nqsi++sGEsGA FUN_000323-T3 71 NDLTTLSYLHEPAVLYNLQVRFLqSNAIYTYCGIVLVAINPYQQLPLYSQDIIAAYSGQSMGDMDPHIFAVAEDAFRAMSRDRQNQSIIVSGESGA 166 79********************73678********************************************************************* PP Myosin_head 97 GKteatKkvlqylasvseskeevekeeveekilqsnPilEafGnAktvrnnnssRFGKyieiefdkkgkiagakietYLLEksRvvkqaeeERnyH 192 GKt+++K+ ++y+asv + ++ +++ve+k+l+snPi+Ea+GnAkt+rn+nssRFGKy+ei+fdk+ +i+ga+++tYLLEksRvv+qa +ERnyH FUN_000323-T3 167 GKTVSAKYAMRYFASVGGASS---ETQVEKKVLASNPIMEAIGNAKTIRNDNSSRFGKYLEISFDKNHQIIGAHMRTYLLEKSRVVFQAVDERNYH 259 ******************999...578********************************************************************* PP Myosin_head 193 iFYqllagaseeekkelkledvkdyaylsqsgeltvdgiddseefketkkaldvlglseeeqkeifrivaailhlGniefkkeakeeqavskdeek 288 iFYql+a + e+k+l+l + +++ yl+q+++ vd +dd e f+e+++a+d+lg+ e++q+ ifri+a+ilh+Gni+++ + +ee+ +s+++ + FUN_000323-T3 260 IFYQLCAACDLPELKDLRLGHQDNFYYLNQGECPYVDDVDDGEGFEEMREAMDLLGIMEDQQQMIFRILAGILHIGNINIQPAGDEESEISDKDVH 355 ***********************************************************************************9999889999999 PP Myosin_head 289 lekaaellgvdaeelekalvkrriktgkevvskalnveqakvardalakaiyerlFdwlvekinkslekkkeekksfiGvLDiaGFEifeknsFEq 384 l++aaellgv+ ++l+k++++r+i t +ev++k+lnv +a++ r+a++k+iy++lF+w+v+ in+sl++++ +++sf+G+LDi+GFE+fe+nsFEq FUN_000323-T3 356 LSIAAELLGVQRNQLKKWMCNRKIVTVQEVLIKPLNVDEANCGREAISKHIYSQLFKWIVQCINNSLSNNA-KQHSFLGILDIYGFETFEVNSFEQ 450 *********************************************************************99.99********************** PP Myosin_head 385 lcinyvnEkLqqlFnelvlklEqeeYvrEgiewefidfgldnqaiidLiekkplGilslLdeecllpkatdetfleklvkefekhakfeksrlkks 480 +ciny+nEkLqq+F ++v+klEqeeYv+E+iew+fi+f +dnq++idLie+k lGil+lLdeec++pk+ d+++++kl+k++ ++++f+k+r +s FUN_000323-T3 451 FCINYANEKLQQQFTQHVFKLEQEEYVKEEIEWSFINF-YDNQPCIDLIESK-LGILDLLDEECKMPKGADRSWVQKLYKNHLNKKHFSKPR--MS 542 **************************************.9***********6.**************************************9..6* PP Myosin_head 481 eakFiikHyAgkveYevegfleKnkDtlnedlvellkkskkkllaelfkeeekeakaeakksekkkkkkkkkkkfktvgskfkeslaeLmktlest 576 e++Fi++H+A++veYev+gf+eKn+Dt+n++++++lk+s+ + + +lf ++e + + +k ++++++k+ +k++++vgs+f+esl++Lm tl++t FUN_000323-T3 543 ETAFIVHHFADNVEYEVKGFVEKNRDTVNKEHLAILKASEYDTVGDLFTDNEA--HLAPRKRSASRSNKNVTKSKRSVGSEFRESLSKLMLTLNNT 636 **************************************************776..45556666666777777789********************* PP Myosin_head 577 nphyvRCikpnekkkakkldeslvleqlrclGvlegirirraGfpnRitfeefvqrYkilakkelkeleklkedakkaveailkkleldkeeykiG 672 phy+RCikpn++k++ +++ ++ ++qlr++Gvle++ri++aG+p+R+ + ef+ rY++l+k e + +++ ++++ ilk+ d +++++G FUN_000323-T3 637 APHYIRCIKPNDRKASFQFNPQRSIQQLRACGVLETVRISAAGYPSRWSYPEFFARYRMLLKFEDIN----RKKPYNTIRVILKRFIKDPDKFQMG 728 *************************************************************998644....47888999***************** PP Myosin_head 673 ktKiFfr 679 ktKiFfr FUN_000323-T3 729 KTKIFFR 735 ******8 PP == domain 2 score: -2.7 bits; conditional E-value: 0.63 Myosin_head 272 fkkeakeeqavskdeeklekaa.....ellgvdae.elekalvkrriktgkevvskaln 324 +++k+++++++ +l+++ el++++ e +ka+++r+i+ + e+vs++l+ FUN_000323-T3 982 RDDSRKQSKTEKE---QLDEINeklkeELMKLKDElAESKAITEREISLRDEIVSQSLE 1037 2222222222222...2333330000033333222023345555555555555555555 PP == domain 3 score: -5.9 bits; conditional E-value: 5.5 Myosin_head 486 ikHyAgkveYevegfleKnkDtlnedl.vellkkskk...kllaelfkeeek.eakaeakksekkkkkkkkkkkfktvgskfkeslaeL 569 + A+++ +ve+ l+ n D l e lkk+++ + l+el+++e++ ++++++ +ek++ ++ + ++ +++ +f +++++L FUN_000323-T3 1259 MASVAKEI-HNVEEMLKNNPDESAYVLqAESLKKANNvlqNELKELMEKEAElKNANDKLWKEKADLQRGRGTSLSAMDGNFNKAVSQL 1346 33333333.45666666666543322202233333320002233333332222222222222333333333333333333444444444 PP >> IQ IQ calmodulin-binding motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 7 2e+04 6 15 .. 233 242 .. 233 243 .. 0.84 2 ? -1.3 0.0 1.4 4e+03 7 20 .. 523 536 .. 522 537 .. 0.91 3 ! 8.3 0.1 0.0011 3.1 1 20 [. 751 770 .. 751 771 .. 0.89 4 ! 22.1 2.9 3.9e-08 0.00011 1 19 [. 774 792 .. 774 794 .. 0.92 5 ! 23.8 1.8 1.1e-08 3.1e-05 2 20 .. 800 818 .. 799 819 .. 0.95 6 ! 14.1 1.0 1.5e-05 0.042 1 18 [. 822 839 .. 822 840 .. 0.95 7 ! 14.9 8.0 8e-06 0.023 4 21 .] 850 867 .. 848 867 .. 0.94 8 ! 7.8 1.3 0.0016 4.6 2 21 .] 871 890 .. 870 890 .. 0.91 9 ? -3.0 0.0 4.8 1.4e+04 6 12 .. 1632 1638 .. 1630 1638 .. 0.87 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 7 IQ 6 kIQaawRGyl 15 +I a+ R yl FUN_000323-T3 233 IIGAHMRTYL 242 5789*****9 PP == domain 2 score: -1.3 bits; conditional E-value: 1.4 IQ 7 IQaawRGylaRkry 20 Q+ ++ +l +k++ FUN_000323-T3 523 VQKLYKNHLNKKHF 536 69********9998 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0011 IQ 1 rkaaikIQaawRGylaRkry 20 r++ i IQ+ +R ++ + y FUN_000323-T3 751 RDSCIMIQKNFRCWREHRLY 770 6899**********999887 PP == domain 4 score: 22.1 bits; conditional E-value: 3.9e-08 IQ 1 rkaaikIQaawRGylaRkr 19 r++ai+IQa+ RGylaR+ FUN_000323-T3 774 RRSAILIQAWLRGYLARRL 792 79***************96 PP == domain 5 score: 23.8 bits; conditional E-value: 1.1e-08 IQ 2 kaaikIQaawRGylaRkry 20 +aai+IQ+++RGy++Rk++ FUN_000323-T3 800 RAAITIQKCYRGYVCRKQF 818 9****************99 PP == domain 6 score: 14.1 bits; conditional E-value: 1.5e-05 IQ 1 rkaaikIQaawRGylaRk 18 rka+++IQ++ RG+ aR+ FUN_000323-T3 822 RKAVVIIQCYTRGMFARR 839 79***************9 PP == domain 7 score: 14.9 bits; conditional E-value: 8e-06 IQ 4 aikIQaawRGylaRkryk 21 a +IQ++wR+y+aRkry+ FUN_000323-T3 850 AKIIQRCWRRYRARKRYR 867 789**************8 PP == domain 8 score: 7.8 bits; conditional E-value: 0.0016 IQ 2 kaaikIQaawRGylaRkryk 21 k +i +Q+++R+++a++++k FUN_000323-T3 871 KNVIYLQSCVRRMRAKRQLK 890 6799*************986 PP == domain 9 score: -3.0 bits; conditional E-value: 4.8 IQ 6 kIQaawR 12 ++Q+++R FUN_000323-T3 1632 VFQSRCR 1638 68****9 PP >> Myosin_N Myosin N-terminal SH3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.6 2.5e-08 7e-05 4 42 .. 11 51 .. 8 53 .. 0.91 2 ? -3.1 0.6 3.5 9.9e+03 20 35 .. 968 985 .. 967 994 .. 0.52 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 2.5e-08 Myosin_N 4 klVWVpDpkegfvkGeikeeegdk..vtVetedGktvtVkk 42 +VW+p+ + ++ Ge++++ g++ +++e+edG ++tV+ FUN_000323-T3 11 ARVWIPHSQVVWIGGELTKDLGENgvLEIELEDGNEITVDV 51 68********************998899999********86 PP == domain 2 score: -3.1 bits; conditional E-value: 3.5 Myosin_N 20 ikeeegdk..vtVetedG 35 ike + + vtVe +d FUN_000323-T3 968 IKELKEELhvVTVERDDS 985 554444332266666443 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 1.8e-05 0.052 13 48 .. 143 179 .. 136 215 .. 0.83 2 ? -2.3 0.0 2.7 7.7e+03 41 130 .. 548 634 .. 546 641 .. 0.59 3 ? -3.4 0.1 6 1.7e+04 94 105 .. 1037 1048 .. 1014 1125 .. 0.62 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.8e-05 AAA_16 13 lallervrsgrp.plvlvsGeaGvGKSalvrellral 48 ++++++ ++ r ++++vsGe+G+GK++ ++ ++r FUN_000323-T3 143 EDAFRAMSRDRQnQSIIVSGESGAGKTVSAKYAMRYF 179 5789988888888***************999998654 PP == domain 2 score: -2.3 bits; conditional E-value: 2.7 AAA_16 41 vrellralera.alvlsgkcdelqrglpyaallealtresllrqllaeseaallaawraalleelaavpalegeeaerllealsrllalaa 130 v+++++ +e + ++++ + d + a+l+a +++ + +l +++ea l+++ r a ++ + v + ++ ++e ls+l+ + FUN_000323-T3 548 VHHFADNVEYEvKGFVEKNRDTV--NKEHLAILKAS-EYDTVGDLFTDNEAHLAPRKRSASRSNKN-VTKSKRSVGSEFRESLSKLMLTLN 634 56666666666544555555555..33345667777.67999999999888776666665444333.444444444888888888874444 PP == domain 3 score: -3.4 bits; conditional E-value: 6 AAA_16 94 aawraalleela 105 +a r++ll+e++ FUN_000323-T3 1037 EAQREQLLAEFE 1048 333333333333 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.0 2.3e-05 0.066 3 32 .. 153 182 .. 151 276 .. 0.72 2 ? -1.8 0.3 1.8 5.1e+03 46 82 .. 991 1039 .. 966 1073 .. 0.55 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.3e-05 AAA_22 3 stagilvltGesGtGKTtllrrlleqldee 32 ++ +++++ GesG+GKT+++++ ++ + ++ FUN_000323-T3 153 RQNQSIIVSGESGAGKTVSAKYAMRYFASV 182 47899***************9988876544 PP == domain 2 score: -1.8 bits; conditional E-value: 1.8 AAA_22 46 spkdllrellralglelek...........elskeell.aalqealkal 82 + k+ l e+ ++l++el k ++++ l+ + + + l+a+ FUN_000323-T3 991 TEKEQLDEINEKLKEELMKlkdelaeskaiTEREISLRdEIVSQSLEAQ 1039 5555566666666666666555566666664444444422333333322 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.024 69 2 22 .. 155 175 .. 154 181 .. 0.87 2 ? 8.6 2.2 0.00069 2 90 168 .. 939 1017 .. 923 1046 .. 0.80 3 ? -2.9 0.0 2.3 6.4e+03 112 167 .. 1467 1523 .. 1464 1547 .. 0.70 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.024 AAA_24 2 klkvliyGpsgiGKTtlaksl 22 ++++++ G+sg GKT ak + FUN_000323-T3 155 NQSIIVSGESGAGKTVSAKYA 175 7899************99987 PP == domain 2 score: 8.6 bits; conditional E-value: 0.00069 AAA_24 90 kaeki.edkgdgkG.ygelkeefrrlldalqelgk..nvvfiahekerkdedeegekytryepklgektakeleeivDlvlrl 168 + +k+ e + ++kG + ++++++ +l ++el++ +vv + + + rk+ ++e+e+ +++ek+++el ++ D++++ FUN_000323-T3 939 VTRKElEHAKQWKGqFELAQTKILQLELEIKELKEelHVVTVERDDSRKQSKTEKEQ----LDEINEKLKEELMKLKDELAES 1017 444445667889***************************************998885....5567777777777777777665 PP == domain 3 score: -2.9 bits; conditional E-value: 2.3 AAA_24 112 rlldalqelgknvvfiahekerkdedeege.kytryepklgektakeleeivDlvlr 167 ++ da+ l+ +++f +++ + + d++++ + + ++ k+ k+ +e +D++++ FUN_000323-T3 1467 SMADAIPGLPAHILFMCIRHADHVNDDRRMqSLLTNSINSIRKVVKKNPENLDILAF 1523 677888899999999999999999999888544444444444455555666666655 PP >> IQ_SCN5A_C SCN5A-like, C-terminal IQ motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.021 61 13 23 .. 755 765 .. 752 771 .. 0.81 2 ? 0.7 0.1 0.19 5.3e+02 10 31 .. 775 796 .. 774 799 .. 0.82 3 ? 8.1 1.2 0.00092 2.6 7 25 .. 797 815 .. 794 820 .. 0.87 4 ? 8.6 2.6 0.00063 1.8 12 27 .. 850 865 .. 841 872 .. 0.85 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.021 IQ_SCN5A_C 13 avIQkAFRkYl 23 + IQk+FR+ + FUN_000323-T3 755 IMIQKNFRCWR 765 57******986 PP == domain 2 score: 0.7 bits; conditional E-value: 0.19 IQ_SCN5A_C 10 rcAavIQkAFRkYlmkvtkkkl 31 r+A++IQ R Yl ++ +k+l FUN_000323-T3 775 RSAILIQAWLRGYLARRLAKDL 796 89*****88899*988877765 PP == domain 3 score: 8.1 bits; conditional E-value: 0.00092 IQ_SCN5A_C 7 eEErcAavIQkAFRkYlmk 25 +E r+A+ IQk +R Y + FUN_000323-T3 797 REKRAAITIQKCYRGYVCR 815 699*************765 PP == domain 4 score: 8.6 bits; conditional E-value: 0.00063 IQ_SCN5A_C 12 AavIQkAFRkYlmkvt 27 A +IQ+ +R+Y+ + + FUN_000323-T3 850 AKIIQRCWRRYRARKR 865 88*********87655 PP >> Mating_N Mating-type protein beta 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.4 0.00025 0.7 10 57 .. 1028 1075 .. 1021 1083 .. 0.91 2 ? -0.4 0.0 0.61 1.7e+03 42 59 .. 1373 1390 .. 1338 1396 .. 0.79 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00025 Mating_N 10 sDedvrqtLdalrkdFfssLrgdsealstFlsawskfdellqschdsL 57 +De+v+q+L+a r+++++ +++ ++ ++ l+ +++++++ q+++d+ FUN_000323-T3 1028 RDEIVSQSLEAQREQLLAEFESERSNHQRVLRDYDRLEQRYQNLQDEM 1075 49**********************99*****************99876 PP == domain 2 score: -0.4 bits; conditional E-value: 0.61 Mating_N 42 awskfdellqschdsLse 59 a + f++++qsc+ +L++ FUN_000323-T3 1373 AVAPFRSRIQSCKGDLEQ 1390 667899999999999987 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.0002 0.58 10 48 .. 144 181 .. 140 192 .. 0.80 2 ? -2.4 0.7 2.4 6.9e+03 78 118 .. 963 1005 .. 954 1047 .. 0.59 3 ? -3.0 0.3 3.5 1e+04 69 113 .. 1210 1253 .. 1200 1268 .. 0.46 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0002 NPHP3_N 10 eefqeWldspsdssllwlsGkpGsGKsvlastvidhlqa 48 ++f++ +++ +++ + +sG+ G+GK+v a++ ++++ + FUN_000323-T3 144 DAFRAMSRDR-QNQSIIVSGESGAGKTVSAKYAMRYFAS 181 6777777664.677889***************9998765 PP == domain 2 score: -2.4 bits; conditional E-value: 2.4 NPHP3_N 78 qlasqlpelreellekl..aedlgldekdlrelweklletlll 118 ql + +el+eel+ ++d+++++k+ +e+++++ e+l + FUN_000323-T3 963 QLELEIKELKEELHVVTveRDDSRKQSKTEKEQLDEINEKLKE 1005 5555556666555433211333444444445555554444432 PP == domain 3 score: -3.0 bits; conditional E-value: 3.5 NPHP3_N 69 ssllrsllhqlasqlpelreelleklaedlgldekdlrelwekll 113 +llr ll q +++ + + ekl+e + d+k +e ++l FUN_000323-T3 1210 LELLRKLLSQRNVDKEAEWDMINEKLKEM-SDDRKRVDEEKKQLR 1253 45666666666544444334444443332.223333333333343 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1640 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3340 (0.13075); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 123 (0.00481503); expected 25.5 (0.001) Passed Fwd filter: 35 (0.00137013); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.77u 0.40s 00:00:01.17 Elapsed: 00:00:00.46 # Mc/sec: 14335.41 // Query: FUN_000324-T1 [L=142] Description: FUN_000324 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0024 19.0 22.4 0.0034 18.6 22.4 1.2 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.0029 18.5 20.8 0.0041 18.0 20.8 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 0.7 10.4 13.2 0.99 9.9 13.2 1.4 1 PMG PMG protein 2.1 9.2 11.6 3.2 8.6 11.6 1.3 1 BAMBI BMP and activin membrane-bound inhibitor (BAMBI 3.5 9.1 20.7 4.8 8.7 20.7 1.2 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 22.4 6.6e-07 0.0034 2 72 .] 21 101 .. 20 101 .. 0.75 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 6.6e-07 Toxin_TOLIP 2 kCytCeeeksnsnCl...ketkCse..sekyCvttvtsa.....kskklisksCsssCeessselgvasvsvsCCqtdlCN 72 +Cy C +++s ++C+ ++++Cs+ e +C t + + + ++ ++k C++ +s++ + +s +vsCC++dlCN FUN_000324-T1 21 SCYFCLSTTSWEDCRnklSIKNCSHihPEMVCATLTMEGtdeekRVTRHYQKICEEPQRCDSTQCKDVSCTVSCCHEDLCN 101 7*************84335799*97325789***99999965443344455666655444577888889***********9 PP >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 20.8 7.9e-07 0.0041 3 81 .. 20 102 .. 18 103 .. 0.78 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 7.9e-07 UPAR_LY6 3 lrCysClgessssccssgs...sC..pkgdtqCvtttiklsgg.gkksslsvkgC..spscpelnetseigsltvtesccqsdlCns 81 ++Cy Cl+++s+++c++ +C ++ +C+t t++ ++ + +++ k C ++c +++ + + ++ t+scc++dlCn+ FUN_000324-T1 20 ISCYFCLSTTSWEDCRNKLsikNCshIHPEMVCATLTMEGTDEeKRVTRHYQKICeePQRCDSTQCK---D-VSCTVSCCHEDLCNK 102 79*************9988899**8667889********9998446666888889643344333333...3.468***********8 PP >> PMG PMG protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 13.2 0.00019 0.99 47 91 .. 61 105 .. 18 127 .. 0.71 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00019 PMG 47 qlgsslldncqetcgeptscqtssvesstsstsvcepspcqrscy 91 ++ +++ +q c ep +c +++++ + s+c++ c +++ FUN_000324-T1 61 DEEKRVTRHYQKICEEPQRCDSTQCKDVSCTVSCCHEDLCNKDFR 105 345567788*******************************98765 PP >> BAMBI BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 11.6 0.00062 3.2 40 103 .. 33 105 .. 7 109 .. 0.61 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00062 BAMBI 40 mckselnacftrvldpqntnsplthgcldsllns....advcssksvrdr...sgssaplecchedmcn..yr 103 c+ +l+ + + p + lt d ++c+ + d+ + s ++ cched+cn +r FUN_000324-T1 33 DCRNKLSIKNCSHIHPEMVCATLTMEGTDEEKRVtrhyQKICEEPQRCDStqcKDVSCTVSCCHEDLCNkdFR 105 47777777777777777777777776666543331111578877665444111456889*********94445 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 20.7 0.00093 4.8 1 78 [. 20 103 .. 20 104 .. 0.70 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00093 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd...gsCfssvekettgkikvvkkgclsre.qdpleCktsnkpeqlnsrieCCktdfCNkn 78 ++Cy C ++ C+++ s +c+ +C +++++ t+++ v++ +++ ++p+ C +++ + + CC++d+CNk+ FUN_000324-T1 20 ISCYfCLSTTswedCRNKLSIKNCSHIhpeMVCATLTMEGTDEEK-RVTR-HYQKIcEEPQRCDSTQCKD-VSCTVSCCHEDLCNKD 103 57988988878899999997777776556799*999999544444.3333.3344447777777766655.466888********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1140 (0.0446271); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.46 # Mc/sec: 1237.80 // Query: FUN_000325-T1 [L=110] Description: FUN_000325 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 449 (0.0175768); expected 510.9 (0.02) Passed bias filter: 302 (0.0118223); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.71s 00:00:01.02 Elapsed: 00:00:00.49 # Mc/sec: 909.67 // Query: FUN_000326-T1 [L=782] Description: FUN_000326 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.8 0.1 0.45 11.1 0.1 1.9 1 Chromo_2 Chromatin organization modifier domain 2 Domain annotation for each model (and alignments): >> Chromo_2 Chromatin organization modifier domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 1.8e-05 0.45 8 31 .. 160 194 .. 155 210 .. 0.69 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 1.8e-05 Chromo_2 8 kRvkkgvaSyEieWkkeehvveg...........e 31 ++ +++S++i+W+ +++ +++ + FUN_000326-T1 160 AVHPTSIPSLDIKWHVAHGQTKRdekrryklkrkK 194 56789****************88887666664431 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (782 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1732 (0.0678019); expected 510.9 (0.02) Passed bias filter: 617 (0.0241535); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 7387.83 // Query: FUN_000327-T1 [L=1495] Description: FUN_000327 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-30 105.6 5.2 3.5e-30 105.6 5.2 3.6 4 Chitin_synth_2 Chitin synthase 6.6e-23 81.1 0.3 4.6e-11 43.2 0.1 2.5 2 SAM_2 SAM domain (Sterile alpha motif) 1.5e-19 70.6 0.2 1.4e-10 41.9 0.0 2.4 2 SAM_1 SAM domain (Sterile alpha motif) 2.7e-16 60.0 0.0 1.2e-15 57.9 0.0 2.0 2 Chitin_synth_1 Chitin synthase-like glycosyltransferase dom 3.4e-14 53.6 2.2 3.4e-14 53.6 2.2 3.0 3 Glyco_trans_2_3 Glycosyl transferase family group 2 3.3e-05 24.2 0.0 5.7e-05 23.4 0.0 1.4 1 Glyco_tranf_2_3 Glycosyltransferase like family 2 0.0001 22.8 0.0 0.00034 21.1 0.0 1.9 2 Glycos_transf_2 Glycosyl transferase family 2 ------ inclusion threshold ------ 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 Glyco_transf_21 Glycosyl transferase family 21 Domain annotation for each model (and alignments): >> Chitin_synth_2 Chitin synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 5.7 0.67 2.1e+03 398 470 .. 87 162 .. 82 220 .. 0.64 2 ? -3.2 0.1 1 3.2e+03 28 70 .. 483 529 .. 465 533 .. 0.65 3 ! 105.6 5.2 1.1e-33 3.5e-30 200 467 .. 612 866 .. 584 879 .. 0.81 4 ! 6.5 0.0 0.0012 4 432 495 .. 925 987 .. 900 999 .. 0.84 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 0.67 Chitin_synth_2 398 vvfieligtvvlPvaiaftlylivasilksklvpvialvllaivlG...lpai.....livltarkleyvawllvyllalP 470 vfi ++ t++lP a+ f + + + ks+ p +++++v G + ++ +i+l ++ + +v +l + FUN_000327-T1 87 TVFIMVVLTLMLPEAVSFFKACWISLFRKSHRWPRAKAIIVGLVAGvleVSGLcyftmIILLSTNLW-----PVVLILMMN 162 5888899999999999998888888888876665555544444444100333311111344444444.....333333332 PP == domain 2 score: -3.2 bits; conditional E-value: 1 Chitin_synth_2 28 iclvtaysegeeglrttldslastdyd...dkrkll.lvvcdGlikG 70 + t y e e+++ + l+sl +d +kr++ + dG ikG FUN_000327-T1 483 YICTTMYREIEQEMEQLLNSLHDIDCArqkSKRQIEsHIFFDGAIKG 529 33468899999999999999988876411133444324566777777 PP == domain 3 score: 105.6 bits; conditional E-value: 1.1e-33 Chitin_synth_2 200 dfyeivlmvdadtkvapdsltrlvaalvkdpeilglcGetkiankkeswvtaiqvfeyyishhlskafesvfGsvtclPGcfslyrikaakgadg 294 d ++l+ dad k + +s++ l+ +++dp++ ++cG t+ + q+f+y i h k + v+Gsv c PGcfs+yr a ++ FUN_000327-T1 612 DENTYILTTDADVKFTHESVEALLDFMARDPTVGAVCGRTHPLGIG--PIVWYQIFDYAIGHWFQKVANHVLGSVLCSPGCFSVYRASALRD--- 701 555789**********************************866554..455679********************************999887... PP Chitin_synth_2 295 ewvPilvspeiveeysenvvdtlhkknllllGedrylttlllktfpkrktvfvpqakaktvaPdkfkvllsqrrrwinstvhnllelvlvrdlc. 388 + Pi+ + +n d l k +Gedr+l tl+++ + + a+ t Pd+f ++ qrrrwi st+ nl+ l+ +l FUN_000327-T1 702 -VLPIYSTN------VDNSFDFLTK----DMGEDRWLCTLMVQA--GWRLDYCAAAEDSTFCPDNFDEFFKQRRRWIPSTLANLIMLISQWKLTv 783 .67776433......4566777766....48**********986..67889*************************************9988853 PP Chitin_synth_2 389 G.tfcfsmrfvvfieli..gtvvlPvaiaftlylivasilksklvpvialvllaivlGlpailivltarkley.vawllvyll 467 G c s f+++ l+ +t++ P +++++++ + + + +v +v+l+ + a++ + t++++++ va ll l+ FUN_000327-T1 784 GnNDCISFAFILYQALLvfSTIIGPSTVILIMASGLSYAHFPIESDVALVVILCTITVGFALICLYTSQEFQLkVAKLLTVLF 866 4257********98876459**********99988777666555555445555555444566677777766542555555554 PP == domain 4 score: 6.5 bits; conditional E-value: 0.0012 Chitin_synth_2 432 vialvllaivlGlpailivltarkleyvawllvyllalPifnfvlPlyafwklddfswGetrvv 495 ++ + la+++G+ + +l+ ++ + + l yl++lP +++ +y+ ++ d swG r FUN_000327-T1 925 NVSSLYLAALIGIFFLAALLHPTEAACLFHGLCYLFCLPSGYLLMIVYSICNMTDRSWGT-REE 987 45566789999999999999999************************************4.543 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.2 0.1 1.4e-14 4.6e-11 9 65 .. 1137 1193 .. 1132 1193 .. 0.96 2 ! 35.5 0.0 3.5e-12 1.1e-08 6 65 .. 1203 1266 .. 1201 1267 .. 0.96 Alignments for each domain: == domain 1 score: 43.2 bits; conditional E-value: 1.4e-14 SAM_2 9 vaeWLrsigleqykdnFkdagitgaelllrlteedLkelGitsvghrkkilkkiqel 65 v eWL+ l+ y +nFkd+g++ ++ + +t +dLk++Gi++ ghrkk+l +i++l FUN_000327-T1 1137 VEEWLHGEFLQLYLKNFKDNGYDNISFIVGITDKDLKAIGIEKRGHRKKLLFAIEKL 1193 89*************************************************999876 PP == domain 2 score: 35.5 bits; conditional E-value: 3.5e-12 SAM_2 6 lesvaeWLrsigleqykdnFkdagitgaell...lrlteedLk.elGitsvghrkkilkkiqel 65 +e+v +WL +gl +y +nFk++g+t ++l + +++e+Lk +++i ++gh k+ k++q++ FUN_000327-T1 1203 PENVEDWLVDLGLDEYWENFKQSGYTEPRMLediKVMNKETLKnDFNIFKPGHLDKLYKALQKV 1266 689************************9999999**************************9987 PP >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.9 0.0 4.3e-14 1.4e-10 6 63 .. 1135 1193 .. 1131 1194 .. 0.96 2 ! 26.5 0.0 2.7e-09 8.6e-06 6 62 .. 1204 1265 .. 1200 1267 .. 0.88 Alignments for each domain: == domain 1 score: 41.9 bits; conditional E-value: 4.3e-14 SAM_1 6 edVgeWLesiglgqYadsF.rkgyidgetLlqlteddLeklgvtllgHrkkIlsaiqrl 63 V eWL+ l+ Y ++F +gy++ + +t++dL+++g+ + gHrkk+l ai++l FUN_000327-T1 1135 TPVEEWLHGEFLQLYLKNFkDNGYDNISFIVGITDKDLKAIGIEKRGHRKKLLFAIEKL 1193 5699****************************************************998 PP == domain 2 score: 26.5 bits; conditional E-value: 2.7e-09 SAM_1 6 edVgeWLesiglgqYadsF.rkgyidgetLlq...lteddLek.lgvtllgHrkkIlsaiqr 62 e V +WL ++gl +Y ++F ++gy++ ++L + + +++L++ ++ ++gH k+ +a+q+ FUN_000327-T1 1204 ENVEDWLVDLGLDEYWENFkQSGYTEPRMLEDikvMNKETLKNdFNIFKPGHLDKLYKALQK 1265 7899**********************99988722256788********************97 PP >> Chitin_synth_1 Chitin synthase-like glycosyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.46 1.5e+03 3 126 .. 484 514 .. 482 539 .. 0.53 2 ! 57.9 0.0 3.7e-19 1.2e-15 147 331 .. 616 778 .. 587 779 .. 0.89 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.46 Chitin_synth_1 3 ivitlynEdeallartlkgvmkniaelcsrkkskvwgkdgWkkvvvcivsDGrkkidervldvlaalGvyqegiakkevngkevtahlfeyttql 97 i+ t+y E e+++ + l+++ FUN_000327-T1 484 ICTTMYREIEQEMEQLLNSL--------------------------------------------------------------------------- 503 55666655555554444443........................................................................... PP Chitin_synth_1 98 svdedlklkseekelvpvqlifclkekna 126 i c ++k++ FUN_000327-T1 504 ------------------HDIDCARQKSK 514 ..................22334444444 PP == domain 2 score: 57.9 bits; conditional E-value: 3.7e-19 Chitin_synth_1 147 vcvlldvGtkpeeksiyklwkafdkdsnvggacGeikaekgkagkkllnPlvaaqnfeyklsnildkpleSvlgyisvlpgafsayRyaalqnek 241 ++++ d+ k +++s+ l+ + +d++vg++cG+++ + P+v q f+y + + +k + vlg + pg fs yR +al++ FUN_000327-T1 616 YILTTDADVKFTHESVEALLDFMARDPTVGAVCGRTHP-------LGIGPIVWYQIFDYAIGHWFQKVANHVLGSVLCSPGCFSVYRASALRDV- 702 67778999999*************************77.......3489*******************************************99. PP Chitin_synth_1 242 gegplekyfkgeklegeseeakifeanmyLAedrilcfelvakkkekwvlkYvksakaetdvpesvaelisqrrrwlngsffaalyslvh 331 l y ++ + ++ ++++++m edr lc +v ++ w+l+Y+ +a +t +p++++e+ +qrrrw+ ++++ + +++ FUN_000327-T1 703 ----LPIYSTN--V---DNSFDFLTKDM--GEDRWLCTLMV---QAGWRLDYCAAAEDSTFCPDNFDEFFKQRRRWIPSTLANLIMLISQ 778 ....5555444..3...24789999997..8******8875...689*********************************9998877765 PP >> Glyco_trans_2_3 Glycosyl transferase family group 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -6.6 6.7 8 2.6e+04 158 195 .. 128 165 .. 26 167 .. 0.56 2 ? -4.1 1.1 4.9 1.6e+04 158 173 .. 370 384 .. 342 423 .. 0.40 3 ! 53.6 2.2 1.1e-17 3.4e-14 1 197 [. 616 844 .. 616 845 .. 0.80 Alignments for each domain: == domain 1 score: -6.6 bits; conditional E-value: 8 Glyco_trans_2_3 158 allrsllwsglplallllllsslsslalvilllallaa 195 +l + +l ++ ++ +++++l s +++ +v++l++++++ FUN_000327-T1 128 GLVAGVLEVSGLCYFTMIILLSTNLWPVVLILMMNAVF 165 33333333444455555555555555555555555544 PP == domain 2 score: -4.1 bits; conditional E-value: 4.9 Glyco_trans_2_3 158 allrsllwsglplall 173 a++ + +++ p++l+ FUN_000327-T1 370 AFA-LPMLFATPVSLA 384 221.111122222222 PP == domain 3 score: 53.6 bits; conditional E-value: 1.1e-17 Glyco_trans_2_3 1 iilllDaDtvlppdslreiaaeme.spevaliqgpivvmnvrnvleelaalffaedhgkdisvrealgdvlpfvGsnavlrwkalqevg..... 88 +il+ DaD +++s++ ++++m+ +p+v+ ++g + + + + ++ +++ +++a+ h++ + lg vl ++G + v+r++al++v FUN_000327-T1 616 YILTTDADVKFTHESVEALLDFMArDPTVGAVCGRTHPLGIGPIV-WYQIFDYAIGHWFQKVANHVLGSVLCSPGCFSVYRASALRDVLpiyst 708 69999*******************66*************876665.7888889999999989999**********************9999999 PP Glyco_trans_2_3 89 ....gwd.ddtsvsEDfdmglrlqrkGyrvrfvpyalvkeespltlkdelrQrkRwalGcl....lll..erkil.......lvsllallrsll 164 ++d ++ +ED +++ + ++G+r+ + +a + p++++ +++Qr+Rw+ l + l ++k+ + + + + l+ FUN_000327-T1 709 nvdnSFDfLTKDMGEDRWLCTLMVQAGWRLDYCAAAEDSTFCPDNFDEFFKQRRRWIPSTLanliM-LisQWKLTvgnndciSFAFILYQALLV 801 99999999999*************************99999******************8875441.134222212333322222223333333 PP Glyco_trans_2_3 165 wsg..lplallllllsslss........lalvilllallaall 197 +s+ p +++l++ s+ls+ alv++l++++++++ FUN_000327-T1 802 FSTiiGPSTVILIMASGLSYahfpiesdVALVVILCTITVGFA 844 3332145555556666666699999999999999999998886 PP >> Glyco_tranf_2_3 Glycosyltransferase like family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 1.8e-08 5.7e-05 132 228 .. 661 765 .. 606 767 .. 0.79 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 1.8e-08 Glyco_tranf_2_3 132 lsalgalefaerhiqlmllrlagg.vlplsGagslirrevlkelg.........gldpeaflltdDkslgrrlkraGfriayapdaavreltps 215 + + ++a h ++ + g vl++ G +s++r+ +l + + +d +++D l+ + +aG+r y+++a+ ++ p FUN_000327-T1 661 WYQIF--DYAIGHWFQKVANHVLGsVLCSPGCFSVYRASALRDVLpiystnvdnSFDFLTKDMGEDRWLCTLMVQAGWRLDYCAAAEDSTFCPD 752 44333..47777777777777777688888********************999988888999******************************** PP Glyco_tranf_2_3 216 slaalvkqrlRwv 228 +++ +kqr+Rw+ FUN_000327-T1 753 NFDEFFKQRRRWI 765 ************7 PP >> Glycos_transf_2 Glycosyl transferase family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.3 0.0 6.5 2.1e+04 2 22 .. 484 505 .. 484 512 .. 0.86 2 ! 21.1 0.0 1.1e-07 0.00034 80 167 .. 615 702 .. 606 703 .. 0.91 Alignments for each domain: == domain 1 score: -4.3 bits; conditional E-value: 6.5 Glycos_transf_2 2 viiptyNe.ekylletleslln 22 +++++y e e+ +++l+sl + FUN_000327-T1 484 ICTTMYREiEQEMEQLLNSLHD 505 6788999999*******99976 PP == domain 2 score: 21.1 bits; conditional E-value: 1.1e-07 Glycos_transf_2 80 dyiaflDaDdevspdwleklvekleedgadvvvgsrvaisgetgeyrrasratesrlpeklrkrllklklpfliggfalyrrealeel 167 yi++ DaD ++ + +e l++++ +d++ ++v++r + g + + ++ + ++++ + +++ + g+f++yr +al+++ FUN_000327-T1 615 TYILTTDADVKFTHESVEALLDFMARDPTVGAVCGRTHPLGIGPIVWYQIFDYAIGHWFQKVANHVLGSVLCSPGCFSVYRASALRDV 702 3***********************************999999999999887799999999999*********************9886 PP >> Glyco_transf_21 Glycosyl transferase family 21 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 8.3e-06 0.026 31 173 .. 614 764 .. 605 765 .. 0.83 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 8.3e-06 Glyco_transf_21 31 ydlllisDsdirvkpdyLtdllaeltd.pkvgLVts..lpvgadakglaaaleaaflntvagvlaaakllglgfalGksmlfrredLeel.... 117 + ++l++D+d++++ + +++ll +++ p+vg V++ p+g ++ + + a+ +++v+ l+ + ++ G + + r ++L+++ FUN_000327-T1 614 NTYILTTDADVKFTHESVEALLDFMARdPTVGAVCGrtHPLGIGPIVWYQIFDYAIGHWFQKVANH-VLGSVLCSPGCFSVYRASALRDVlpiy 706 679********************99887*******7336888888877788888888999999999.66789****************994444 PP Glyco_transf_21 118 .....GGfealgdyLAeDyalgklvraaglkvalssrpveqtsvprsaeslrevlaRqlRW 173 f l +++ eD l +l+ +ag++++ + + +t p + + e+++ RW FUN_000327-T1 707 stnvdNSFDFLTKDMGEDRWLCTLMVQAGWRLDYCAAAEDSTFCP---DNFDEFFKQRRRW 764 44444467889************************9985676666...4688888888888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1495 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1466 (0.0573889); expected 510.9 (0.02) Passed bias filter: 729 (0.0285379); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.58u 0.39s 00:00:00.97 Elapsed: 00:00:00.43 # Mc/sec: 13932.22 // Query: FUN_000328-T1 [L=958] Description: FUN_000328 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-14 51.7 33.4 4.6e-11 42.3 13.2 3.4 3 DUF7885 Leucine Rich Repeat Domain of unknown function 1.3e-12 47.3 27.7 0.1 13.2 0.0 11.6 13 LRR_6 Leucine Rich repeat 1.7e-07 31.8 18.2 0.036 14.8 0.1 8.1 9 LRR_4 Leucine Rich repeats (2 copies) 9.7e-07 29.1 27.7 0.0042 17.3 7.7 5.3 5 LRR_At5g56370 FBD-associated F-box protein At5g56370, LRR re ------ inclusion threshold ------ 0.063 13.5 11.5 0.14 12.4 0.1 5.7 7 LRR_8 Leucine rich repeat 0.13 12.8 15.2 0.42 11.0 0.5 4.7 4 LRR_RPS2 Plant disease resistance protein RPS2-like, le 3.1 7.9 8.0 35 4.5 0.2 4.1 4 LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain Domain annotation for each model (and alignments): >> DUF7885 Leucine Rich Repeat Domain of unknown function (DUF7885) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 5.0 2.1e-07 0.00078 258 361 .. 63 168 .. 58 178 .. 0.87 2 ? 0.8 0.6 0.047 1.7e+02 343 376 .. 189 224 .. 181 235 .. 0.77 3 ! 42.3 13.2 1.3e-14 4.6e-11 287 494 .. 625 824 .. 614 853 .. 0.83 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 2.1e-07 DUF7885 258 lllaegckrlesvrlgGfskvrdaGyaallqsCkdlkkfevstasll.sdltfldldeaatkltevrlvscslltseta.islssCknlevldlsg 351 llla +l+ ++l+ ++ aG + C++l+ ++ + l f l++ a++lt + l +++++ ++ + l C l+ l+lsg FUN_000328-T1 63 LLLALAPPHLRRLKLTNCNRLSCAGLQRTVAYCQQLQTLDFRECIHLlHPTVFCCLKDKASNLTSLSLENSEVVSDDIVqVALMCCPALKHLNLSG 158 677778889999*****************************99876515666889*******************9997527899************ PP DUF7885 352 CrsiadsGla 361 C+s+ ds +a FUN_000328-T1 159 CQSLTDSAFA 168 ******9875 PP == domain 2 score: 0.8 bits; conditional E-value: 0.047 DUF7885 343 nlevldlsgCrsiadsGlasiskls..kltlldlaG 376 +l +d+sgC+si + ++ + ++ l ++la FUN_000328-T1 189 HLTSVDISGCHSITTKAIKCLVAICgpTLKHINLAC 224 57789*********9999999999833355566654 PP == domain 3 score: 42.3 bits; conditional E-value: 1.3e-14 DUF7885 287 lqsCkdlkkfevstasllsdltfldldeaatkltevrlvscslltsetaisls.sCknlevldlsgCrsiadsGlasisklskltlldlaGaditd 381 ++C lk+f +s ++ d + + + ++l + lv+c+ l s ++ C +l +dl+g + d+G++ +++ l +l la a itd FUN_000328-T1 625 TRACNCLKHFSISGN-VFDDEDLVYILKNEPELESLTLVNCENLSSISLSTIPvYCPKLSSFDLQGMCFVTDHGFMPLTRSNNLKSLRLAEASITD 719 479********9866.66777777777799***************9877777526***************************************** PP DUF7885 382 aGlsalGnGss.pisslclrgCkritdrGiaslllgsgvinktlvaldlgylprisdravvliakaceeisslClrncllitdaslealgslehns 476 + l ++ nG +++ l + C +td+G+++++ +s + l l l s + + +a++c+ + sl + ++td+ l+ l+ + FUN_000328-T1 720 STLESVANGCGdKLKELDISWCEDLTDQGMSNMVAKS---CSCLEHLSLRQCD-ASHLTFISLAQNCHFVASLNIAGVTYLTDEILDNLARNM--- 808 ******999763799**********************...7888888888876.89999***************************9998654... PP DUF7885 477 gkrslrkldlsyCsrlsr 494 l+ +d+s s+l+ FUN_000328-T1 809 --PLLKDIDVSWNSSLTD 824 ..3456666666665554 PP >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.034 1.2e+02 3 15 .. 70 83 .. 68 89 .. 0.81 2 ? -2.6 0.0 3.2 1.2e+04 2 13 .. 95 106 .. 94 106 .. 0.80 3 ? -0.1 0.0 0.52 1.9e+03 3 18 .. 123 139 .. 121 142 .. 0.78 4 ! 8.7 0.0 0.00077 2.8 2 18 .. 148 165 .. 147 166 .. 0.87 5 ! 10.8 0.0 0.00016 0.59 3 23 .. 188 209 .. 188 210 .. 0.92 6 ? 0.1 0.0 0.42 1.6e+03 3 15 .. 215 227 .. 215 228 .. 0.85 7 ? -2.2 0.0 2.4 8.6e+03 10 18 .. 450 458 .. 449 458 .. 0.78 8 ! 8.7 0.0 0.00078 2.9 2 23 .. 628 649 .. 627 650 .. 0.91 9 ? 3.2 0.0 0.045 1.6e+02 2 22 .. 704 724 .. 703 726 .. 0.84 10 ! 13.2 0.0 2.9e-05 0.1 4 22 .. 732 751 .. 732 753 .. 0.91 11 ? 1.5 0.3 0.15 5.6e+02 2 14 .. 757 769 .. 756 769 .. 0.90 12 ? -2.7 0.1 3.5 1.3e+04 4 14 .. 772 782 .. 771 804 .. 0.71 13 ! 6.1 0.1 0.0053 19 3 20 .. 809 827 .. 807 831 .. 0.87 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.034 LRR_6 3 ttLteLdLsgNd.I 15 ++L+ L L++++ + FUN_000328-T1 70 PHLRRLKLTNCNrL 83 8**********966 PP == domain 2 score: -2.6 bits; conditional E-value: 3.2 LRR_6 2 nttLteLdLsgN 13 ++ L++Ld++ + FUN_000328-T1 95 CQQLQTLDFREC 106 7779****9876 PP == domain 3 score: -0.1 bits; conditional E-value: 0.52 LRR_6 3 ttLteLdLsgNd.IgDe 18 ++Lt+L L + + ++D+ FUN_000328-T1 123 SNLTSLSLENSEvVSDD 139 79******988877776 PP == domain 4 score: 8.7 bits; conditional E-value: 0.00077 LRR_6 2 nttLteLdLsgNd.IgDe 18 ++ L++L+Lsg++ ++D+ FUN_000328-T1 148 CPALKHLNLSGCQsLTDS 165 5669*********99995 PP == domain 5 score: 10.8 bits; conditional E-value: 0.00016 LRR_6 3 ttLteLdLsgNd.IgDeGleaL 23 ++Lt++d+sg++ I+ + +++L FUN_000328-T1 188 CHLTSVDISGCHsITTKAIKCL 209 7**************9999887 PP == domain 6 score: 0.1 bits; conditional E-value: 0.42 LRR_6 3 ttLteLdLsgNdI 15 +tL++ +L++ ++ FUN_000328-T1 215 PTLKHINLACTGV 227 69*******9875 PP == domain 7 score: -2.2 bits; conditional E-value: 2.4 LRR_6 10 LsgNdIgDe 18 Ls+++++ e FUN_000328-T1 450 LSCCNLTTE 458 899999865 PP == domain 8 score: 8.7 bits; conditional E-value: 0.00078 LRR_6 2 nttLteLdLsgNdIgDeGleaL 23 +++L++ +sgN ++De l+ + FUN_000328-T1 628 CNCLKHFSISGNVFDDEDLVYI 649 99***************99876 PP == domain 9 score: 3.2 bits; conditional E-value: 0.045 LRR_6 2 nttLteLdLsgNdIgDeGlea 22 +++L++L L+ I+D+ le+ FUN_000328-T1 704 SNNLKSLRLAEASITDSTLES 724 789************986665 PP == domain 10 score: 13.2 bits; conditional E-value: 2.9e-05 LRR_6 4 tLteLdLsgNd.IgDeGlea 22 +L+eLd+s+++ ++D G++ FUN_000328-T1 732 KLKELDISWCEdLTDQGMSN 751 59***************985 PP == domain 11 score: 1.5 bits; conditional E-value: 0.15 LRR_6 2 nttLteLdLsgNd 14 +++L++L L+ +d FUN_000328-T1 757 CSCLEHLSLRQCD 769 89*******9997 PP == domain 12 score: -2.7 bits; conditional E-value: 3.5 LRR_6 4 tLteLdLsgNd 14 +Lt L+ N+ FUN_000328-T1 772 HLTFISLAQNC 782 66666666664 PP == domain 13 score: 6.1 bits; conditional E-value: 0.0053 LRR_6 3 ttLteLdLsgNd.IgDeGl 20 + L+ d+s+N ++D+G+ FUN_000328-T1 809 PLLKDIDVSWNSsLTDDGI 827 56999*************7 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.3 0.1 0.0096 35 1 30 [. 70 103 .. 70 110 .. 0.66 2 ! 14.8 0.1 9.9e-06 0.036 2 38 .. 124 164 .. 123 168 .. 0.81 3 ? -0.8 0.0 0.81 2.9e+03 14 14 .. 202 202 .. 188 234 .. 0.48 4 ? -2.0 0.0 2 7.2e+03 2 18 .. 216 232 .. 215 240 .. 0.59 5 ? -0.5 0.1 0.65 2.4e+03 21 33 .. 627 639 .. 599 647 .. 0.68 6 ! 10.4 0.1 0.00025 0.9 1 32 [. 654 689 .. 654 695 .. 0.83 7 ? 3.2 0.1 0.044 1.6e+02 2 30 .. 706 738 .. 705 746 .. 0.74 8 ? 5.1 0.1 0.012 43 2 42 .. 732 773 .. 731 777 .. 0.80 9 ? -1.2 0.1 1.1 4e+03 38 38 .. 798 798 .. 771 824 .. 0.51 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0096 LRR_4 1 pnLetLdLsn.Nritdidp.ls.k.LpnLetLdL 30 p+L++L L n Nr++ ++ + +L+tLd FUN_000328-T1 70 PHLRRLKLTNcNRLSCAGLqRTvAyCQQLQTLDF 103 6788888885258886666522444888888887 PP == domain 2 score: 14.8 bits; conditional E-value: 9.9e-06 LRR_4 2 nLetLdLsnNritdidp....lskLpnLetLdLsgNnkitd 38 nL++L+L n + + d l ++p L++L+Lsg+ +td FUN_000328-T1 124 NLTSLSLENSEVVSDDIvqvaLMCCPALKHLNLSGCQSLTD 164 9********988877775454448************88877 PP == domain 3 score: -0.8 bits; conditional E-value: 0.81 LRR_4 14 t 14 t FUN_000328-T1 202 T 202 2 PP == domain 4 score: -2.0 bits; conditional E-value: 2 LRR_4 2 nLetLdLsnNritdidp 18 L++++L+ + + i + FUN_000328-T1 216 TLKHINLACTGVDCIAL 232 56666666655555544 PP == domain 5 score: -0.5 bits; conditional E-value: 0.65 LRR_4 21 kLpnLetLdLsgN 33 + L++ ++sgN FUN_000328-T1 627 ACNCLKHFSISGN 639 3777888888777 PP == domain 6 score: 10.4 bits; conditional E-value: 0.00025 LRR_4 1 pnLetLdLsnN.ritdidp...lskLpnLetLdLsg 32 p Le+L L n+ ++++i++ + +p+L + dL g FUN_000328-T1 654 PELESLTLVNCeNLSSISLstiPVYCPKLSSFDLQG 689 689****************765447*********76 PP == domain 7 score: 3.2 bits; conditional E-value: 0.044 LRR_4 2 nLetLdLsnNritdidpls...k.LpnLetLdL 30 nL++L L+ +itd + s + +L++Ld+ FUN_000328-T1 706 NLKSLRLAEASITDSTLESvanGcGDKLKELDI 738 99******999**96663355543666999998 PP == domain 8 score: 5.1 bits; conditional E-value: 0.012 LRR_4 2 nLetLdLs..nNritdidpls...k.LpnLetLdLsgNnkitdlsdL 42 +L++Ld+s +td + + k + Le+L+L ++ d s+L FUN_000328-T1 732 KLKELDISwcE-DLTDQGMSNmvaKsCSCLEHLSLRQC----DASHL 773 69999999754.89999997777754*********888....76655 PP == domain 9 score: -1.2 bits; conditional E-value: 1.1 LRR_4 38 d 38 d FUN_000328-T1 798 D 798 1 PP >> LRR_At5g56370 FBD-associated F-box protein At5g56370, LRR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 7.7 1.1e-06 0.0042 4 118 .. 63 181 .. 60 194 .. 0.82 2 ! 11.6 0.4 6e-05 0.22 59 112 .. 627 679 .. 566 695 .. 0.72 3 ! 8.0 0.1 0.00079 2.9 36 93 .. 679 738 .. 674 745 .. 0.79 4 ! 5.1 0.9 0.006 22 39 95 .. 733 792 .. 731 800 .. 0.66 5 ? 0.4 0.2 0.16 6e+02 41 90 .. 787 839 .. 777 850 .. 0.69 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 1.1e-06 LRR_At5g56370 4 WlrslalkgvqeLvlvnrpwpldlplpasllrcaslrrlylgvwrf...dtdalpraasFpnLreLgLsrvsiserdL.halLarcpvLesLsllg 95 +l la +++ L l n+++ + l ++ c++l++l + + + +t + + nL+ L+L++ + ++d+ + L +cp+L++L+l g FUN_000328-T1 63 LLLALAPPHLRRLKLTNCNRLSCAGLQRTVAYCQQLQTLDFRECIHllhPTVFCCLKDKASNLTSLSLENSEVVSDDIvQVALMCCPALKHLNLSG 158 6677888899********999999*****************998643435566667889***********987655552778************** PP LRR_At5g56370 96 srnglrrlrirsrsLrcvllwes 118 +++ ++ s+s + + + s FUN_000328-T1 159 CQSLTDSAFAFSSSTSSSGKCYS 181 99988888888888777776655 PP == domain 2 score: 11.6 bits; conditional E-value: 6e-05 LRR_At5g56370 59 sFpnLreLgLsrvsiserdLhalLarcpvLesLsllgsrnglrrlrirsrsLrc 112 + +L++ ++s ++ ++dL ++L++ p LesL+l+++ +l+++ ++ + c FUN_000328-T1 627 ACNCLKHFSISGNVFDDEDLVYILKNEPELESLTLVNCE-NLSSISLSTIPVYC 679 5679*******************************9875.67777776655555 PP == domain 3 score: 8.0 bits; conditional E-value: 0.00079 LRR_At5g56370 36 caslrrlylgvwrfdtd.alpraasFpnLreLgLsrvsiserdLhalLarc.pvLesLsl 93 c++l + l ++f td ++ nL+ L L + si++++L+++ ++c +L+ L + FUN_000328-T1 679 CPKLSSFDLQGMCFVTDhGFMPLTRSNNLKSLRLAEASITDSTLESVANGCgDKLKELDI 738 888999999888885541445567899***********************9446777766 PP == domain 4 score: 5.1 bits; conditional E-value: 0.006 LRR_At5g56370 39 lrrlylgvwr.fdtdalpr..aasFpnLreLgLsrvsiserdLhalLarcpvLesLsllg 95 l+ l +++++ ++++ +++ a s +L++L+L++++ s ++ +l ++c+ sL++ g FUN_000328-T1 733 LKELDISWCEdLTDQGMSNmvAKSCSCLEHLSLRQCDASHLTFISLAQNCHFVASLNIAG 792 556666655522333343322446788888888888888888888888888888887765 PP == domain 5 score: 0.4 bits; conditional E-value: 0.16 LRR_At5g56370 41 rlylgvwrfdtdalpr..aasFpnLreLgLs.rvsiserdLhalLarcpvLes 90 +l+++ ++ td++ + a + p L++++ s + s++++ + +lL++c +L+ FUN_000328-T1 787 SLNIAGVTYLTDEILDnlARNMPLLKDIDVSwNSSLTDDGICSLLECCLKLNR 839 444444444444444412447999****997368899***********99976 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.031 1.1e+02 1 49 [. 70 119 .. 70 120 .. 0.74 2 ? 12.4 0.1 3.9e-05 0.14 25 60 .. 123 160 .. 119 160 .. 0.88 3 ? -3.9 0.0 4.7 1.7e+04 27 35 .. 631 639 .. 623 642 .. 0.53 4 ? -0.0 0.1 0.29 1.1e+03 1 32 [. 654 687 .. 654 703 .. 0.73 5 ? -0.7 0.0 0.47 1.7e+03 26 39 .. 706 719 .. 700 742 .. 0.48 6 ? -2.3 0.0 1.5 5.4e+03 36 46 .. 759 769 .. 753 781 .. 0.48 7 ? -2.5 0.1 1.8 6.6e+03 22 59 .. 806 819 .. 799 823 .. 0.56 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.031 LRR_8 1 pnLrsLdLssNr.lt..slddgaFkglsnLkvLdLsnNllttlspgafsgLp 49 p+Lr+L L++ + l+ +l+ ++ + +++L++Ld+++ ++ l+p +f +L+ FUN_000328-T1 70 PHLRRLKLTNCNrLScaGLQRTVAY-CQQLQTLDFRE-CIHLLHPTVFCCLK 119 7899999988775652245555555.99999999987.69999999999885 PP == domain 2 score: 12.4 bits; conditional E-value: 3.9e-05 LRR_8 25 snLkvLdLsnNlltt..lspgafsgLpsLrsLdLsgNr 60 snL++L+L n + + + + a++++p+L++L+Lsg++ FUN_000328-T1 123 SNLTSLSLENSEVVSddIVQVALMCCPALKHLNLSGCQ 160 89*********76655799****************986 PP == domain 3 score: -3.9 bits; conditional E-value: 4.7 LRR_8 27 LkvLdLsnN 35 Lk++++s N FUN_000328-T1 631 LKHFSISGN 639 333333333 PP == domain 4 score: -0.0 bits; conditional E-value: 0.29 LRR_8 1 pnLrsLdLssNr.ltslddgaFkg.lsnLkvLdL 32 p+L+sL+L + l+s++ ++ +++L ++dL FUN_000328-T1 654 PELESLTLVNCEnLSSISLSTIPVyCPKLSSFDL 687 5788888887777888877766544666666665 PP == domain 5 score: -0.7 bits; conditional E-value: 0.47 LRR_8 26 nLkvLdLsnNlltt 39 nLk+L L + ++t FUN_000328-T1 706 NLKSLRLAEASITD 719 55555555555543 PP == domain 6 score: -2.3 bits; conditional E-value: 1.5 LRR_8 36 llttlspgafs 46 +l++ls + ++ FUN_000328-T1 759 CLEHLSLRQCD 769 34444444333 PP == domain 7 score: -2.5 bits; conditional E-value: 1.8 LRR_8 22 kglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgN 59 +++ p L+ +d+s N FUN_000328-T1 806 RNM------------------------PLLKDIDVSWN 819 344........................55555555544 PP >> LRR_RPS2 Plant disease resistance protein RPS2-like, leucine-rich repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 4.6 0.031 1.1e+02 29 137 .. 71 163 .. 66 174 .. 0.57 2 ? -2.7 0.0 1.9 7.1e+03 124 137 .. 189 202 .. 184 204 .. 0.80 3 ? 0.1 0.0 0.27 9.8e+02 29 139 .. 655 670 .. 640 686 .. 0.67 4 ? 11.0 0.5 0.00012 0.42 21 72 .. 724 775 .. 704 830 .. 0.69 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.031 LRR_RPS2 29 kLksLtvekckklsnavfpsnllklLknLeeLevrncdsle..eifdleglsedelvtkeeeklvklafqLkkLklenLpkLkhVwnkdpq.gils 121 +L+ L+ ++c+ ls+a ++ + ++L++L+ r+c l ++f + a++L +L+l ++ + V ++ q +++ FUN_000328-T1 71 HLRRLKLTNCNRLSCAG-LQRTVAYCQQLQTLDFRECIHLLhpTVFCCLKD---------------KASNLTSLSL---ENSEVVSDDIVQvALMC 147 57888888888888654.446777788888888888866541134432222...............2345555544...33333333333334556 PP LRR_RPS2 122 fqnLqsvevenCesLk 137 ++ L++++ + C+sL+ FUN_000328-T1 148 CPALKHLNLSGCQSLT 163 6666666666666665 PP == domain 2 score: -2.7 bits; conditional E-value: 1.9 LRR_RPS2 124 nLqsvevenCesLk 137 +L+sv+++ C+s++ FUN_000328-T1 189 HLTSVDISGCHSIT 202 68888888888876 PP == domain 3 score: 0.1 bits; conditional E-value: 0.27 LRR_RPS2 29 kLksLtvekckklsnavfpsnllklLknLeeLevrncdsleeifdleglsedelvtkeeeklvklafqLkkLklenLpkLkhVwnkdpqgilsfqn 124 +L+sLt +c++ls FUN_000328-T1 655 ELESLTLVNCENLS---------------------------------------------------------------------------------- 668 34444444444444.................................................................................. PP LRR_RPS2 125 LqsvevenCesLksl 139 s+ FUN_000328-T1 669 -------------SI 670 .............43 PP == domain 4 score: 11.0 bits; conditional E-value: 0.00012 LRR_RPS2 21 pveensfskLksLtvekckklsnavfpsnllklLknLeeLevrncdsleeif 72 +v + + kLk+L ++ c+ l ++ ++ + k + Le+L+ r+cd f FUN_000328-T1 724 SVANGCGDKLKELDISWCEDLTDQGMSNMVAKSCSCLEHLSLRQCDASHLTF 775 34567999**************998888888999***********9877776 PP >> LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.2 0.0095 35 44 85 .. 118 159 .. 103 166 .. 0.85 2 ? 4.1 0.1 0.013 48 35 93 .. 615 672 .. 584 692 .. 0.58 3 ? -0.3 0.0 0.29 1.1e+03 39 88 .. 670 718 .. 663 739 .. 0.77 4 ? 0.5 0.1 0.16 5.9e+02 31 87 .. 763 821 .. 749 836 .. 0.80 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.0095 LRR_NXF1-5 44 ieenipeLlsLnlsnnklykLdglsdivqkapnlkiLnLskn 85 ++++ ++L+sL l n ++++ d ++ p lk LnLs FUN_000328-T1 118 LKDKASNLTSLSLENSEVVSDDIVQVALMCCPALKHLNLSGC 159 5778899********9999987777778889********965 PP == domain 2 score: 4.1 bits; conditional E-value: 0.013 LRR_NXF1-5 35 ncmaavlkiieenipeLlsLnlsnnklykLdglsdivqkapnlkiLnLsknelksereL 93 + a lki + + L ++ +s n + ++l i ++ p+l +L L + e s+ L FUN_000328-T1 615 QLGMACLKIFTRACNCLKHFSISGNV-FDDEDLVYILKNEPELESLTLVNCENLSSISL 672 44456666666666666666666653.44466666666666666666665554444444 PP == domain 3 score: -0.3 bits; conditional E-value: 0.29 LRR_NXF1-5 39 avlkiieenipeLlsLnlsnnklykLdglsdivqkapnlkiLnLsknelk 88 +l i +p+L s++l+ + ++ +g+ ++ ++ nlk+L L++ ++ FUN_000328-T1 670 ISLSTIPVYCPKLSSFDLQGMCFVTDHGFMPLT-RSNNLKSLRLAEASIT 718 566777778899999999999999999998876.5789999999988764 PP == domain 4 score: 0.5 bits; conditional E-value: 0.16 LRR_NXF1-5 31 lnrrncmaavlkiie..enipeLlsLnlsnnklykLdglsdivqkapnlkiLnLsknel 87 l+ r+c a+ l i +n+ + sLn+ + + + l +++++ p lk ++ s n+ FUN_000328-T1 763 LSLRQCDASHLTFISlaQNCHFVASLNIAGVTYLTDEILDNLARNMPLLKDIDVSWNSS 821 566777777777664337888899999999999999999999999*****999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (958 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 750 (0.02936); expected 510.9 (0.02) Passed bias filter: 446 (0.0174594); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.39u 0.43s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 9230.41 // Query: FUN_000329-T1 [L=168] Description: FUN_000329 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-30 105.8 16.9 1.5e-16 60.9 4.4 2.1 2 EF-hand_7 EF-hand domain pair 5.8e-27 91.7 21.0 1.5e-08 34.1 2.1 4.2 4 EF-hand_1 EF hand domain 5.2e-24 82.1 15.2 1.1e-07 31.4 0.2 4.3 4 EF-hand_6 EF-hand domain 1.4e-16 60.4 17.7 8.6e-09 35.5 0.3 4.1 4 EF-hand_8 EF-hand domain pair 2.3e-13 49.4 14.4 9.3e-05 22.2 1.6 4.5 4 EF-hand_5 EF hand 5.8e-13 49.6 2.7 1.2e-05 26.2 0.0 2.1 2 EF-hand_9 EF-hand domain 3.1e-10 40.9 7.6 3.2e-05 24.7 0.3 2.0 2 AIF-1 Allograft inflammatory factor 1 0.00025 21.5 0.0 0.82 10.2 0.0 2.1 2 EF-hand_SWAP70_N Switch-associated protein 70-like, N-termi 0.00042 21.2 10.1 0.41 11.5 2.1 3.6 2 EF-hand_FSTL1 Follistatin-related protein 1, EF-hand dom 0.00081 19.8 5.7 0.88 10.0 0.4 3.2 3 EH EH domain 0.0013 18.8 4.0 0.044 13.9 0.9 2.9 2 EF_EFCAB10_C EFCAB10, C-terminal EF-hand 0.0062 16.8 0.0 0.012 15.8 0.0 1.5 1 SUB1_ProdP9 SUB1 protease Prodomain ProdP9 ------ inclusion threshold ------ 0.012 16.0 3.8 2 8.8 0.1 3.7 4 Caleosin Caleosin related protein 0.019 15.3 0.8 0.87 9.9 0.1 2.4 2 EF-hand_EFHB_C EFHB C-terminal EF-hand domain 0.026 15.4 2.7 1.5 9.7 0.2 2.2 2 EF-hand_14 EF-hand domain 0.034 14.5 2.0 0.034 14.5 2.0 3.1 3 FF_PRPF40A PRPF40A-like, FF domain 0.038 14.3 1.5 0.12 12.7 0.4 2.2 2 UBAP-1_UBA2 Ubiquitin-associated protein 1, UBA2 domai 0.056 14.5 0.2 0.056 14.5 0.2 2.1 2 MgtE_N MgtE intracellular N domain 0.1 13.4 3.6 2 9.3 0.2 2.5 2 SPARC_Ca_bdg Secreted protein acidic and rich in cystei 0.14 12.5 1.2 1.8 8.8 0.1 2.0 2 SurA_N_3 SurA-like N-terminal domain 0.15 12.9 0.6 11 6.9 0.0 3.0 3 SRI SRI (Set2 Rpb1 interacting) domain 0.66 10.4 0.1 0.66 10.4 0.1 2.1 3 BAHCC1-like_Tudor BAHCC1-like, Tudor domain Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.0 4.6 1.7e-16 1.9e-13 2 67 .] 29 92 .. 28 92 .. 0.96 2 ! 60.9 4.4 1.3e-19 1.5e-16 2 67 .] 102 165 .. 101 165 .. 0.96 Alignments for each domain: == domain 1 score: 51.0 bits; conditional E-value: 1.7e-16 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlelys 67 +++keaF+l+D+d+d +d+ elk ++r +g+++++ +v +++k+ D + G+i+f++F e+++ FUN_000329-T1 29 QEIKEAFDLFDTDKDRAIDYHELKVAMR--ALGFDVKKVDVLKIMKDYDRESTGKITFDDFNEVMT 92 79**********************9999..9*******************************9985 PP == domain 2 score: 60.9 bits; conditional E-value: 1.3e-19 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlelys 67 e+ ++aF+l+D d++G+++ l+++ r e+ge+++dee++++++efD+d+dG i+ eEFl++++ FUN_000329-T1 102 EEVFKAFRLFDDDDSGKISLRNLRRVAR--ELGENMTDEELRAMIDEFDKDGDGEINEEEFLAIMT 165 67789***********************..*********************************995 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.3 1e-10 1.2e-07 1 29 [] 30 58 .. 30 58 .. 0.96 2 ! 20.2 1.3 3.5e-07 0.0004 2 27 .. 67 92 .. 66 93 .. 0.92 3 ! 18.5 0.1 1.2e-06 0.0014 1 28 [. 103 130 .. 103 131 .. 0.89 4 ! 34.1 2.1 1.3e-11 1.5e-08 1 27 [. 139 165 .. 139 167 .. 0.95 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 1e-10 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkkl 29 e+ke+F++fD+D+d Id+ E+k ++++l FUN_000329-T1 30 EIKEAFDLFDTDKDRAIDYHELKVAMRAL 58 79************************975 PP == domain 2 score: 20.2 bits; conditional E-value: 3.5e-07 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellk 27 + +i++ +D+ GkI+f++f e+++ FUN_000329-T1 67 VLKIMKDYDRESTGKITFDDFNEVMT 92 679*********************97 PP == domain 3 score: 18.5 bits; conditional E-value: 1.2e-06 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkk 28 e+ ++Fr+fD D +GkI++ ++++ ++ FUN_000329-T1 103 EVFKAFRLFDDDDSGKISLRNLRRVARE 130 6789***************999998765 PP == domain 4 score: 34.1 bits; conditional E-value: 1.3e-11 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellk 27 el+ +++efDkDgdG I+ eEf+++++ FUN_000329-T1 139 ELRAMIDEFDKDGDGEINEEEFLAIMT 165 799**********************97 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 0.2 9.4e-11 1.1e-07 1 30 [] 30 59 .. 30 59 .. 0.97 2 ! 14.5 0.4 2.7e-05 0.032 4 27 .. 69 92 .. 66 97 .. 0.87 3 ! 22.6 0.3 6.8e-08 7.9e-05 3 30 .] 105 132 .. 103 132 .. 0.92 4 ! 22.7 0.4 6.1e-08 7e-05 1 27 [. 139 165 .. 139 167 .. 0.92 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 9.4e-11 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrslG 30 e++eaF+lfD+d+d i+++El+ a+r+lG FUN_000329-T1 30 EIKEAFDLFDTDKDRAIDYHELKVAMRALG 59 69*************************998 PP == domain 2 score: 14.5 bits; conditional E-value: 2.7e-05 EF-hand_6 4 eaFklfDkdgdGyisleElraalr 27 ++ k +D++ +G+i+++++ ++++ FUN_000329-T1 69 KIMKDYDRESTGKITFDDFNEVMT 92 67899**************99997 PP == domain 3 score: 22.6 bits; conditional E-value: 6.8e-08 EF-hand_6 3 reaFklfDkdgdGyisleElraalrslG 30 +aF+lfD d++G+isl lr++ r lG FUN_000329-T1 105 FKAFRLFDDDDSGKISLRNLRRVARELG 132 68*********************99987 PP == domain 4 score: 22.7 bits; conditional E-value: 6.1e-08 EF-hand_6 1 elreaFklfDkdgdGyisleElraalr 27 elr + + fDkdgdG i+ eE+ a+++ FUN_000329-T1 139 ELRAMIDEFDKDGDGEINEEEFLAIMT 165 6889999*****************997 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.5 0.001 1.2 24 51 .. 28 55 .. 17 56 .. 0.89 2 ! 17.6 1.3 2.9e-06 0.0033 2 52 .. 43 92 .. 42 94 .. 0.92 3 ! 21.9 1.9 1.3e-07 0.00015 1 44 [. 78 121 .. 78 123 .. 0.91 4 ! 35.5 0.3 7.4e-12 8.6e-09 9 51 .. 123 164 .. 121 166 .. 0.93 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.001 EF-hand_8 24 edevdtlfrefDtDgdGkisfeeFcvll 51 ++e+ + f fDtD+d +i+ e++v++ FUN_000329-T1 28 KQEIKEAFDLFDTDKDRAIDYHELKVAM 55 89**************999999999887 PP == domain 2 score: 17.6 bits; conditional E-value: 2.9e-06 EF-hand_8 2 kgvItresLkrilalLglqdlsedevdtlfrefDtDgdGkisfeeFcvlle 52 + I+ ++Lk ++++Lg +++ +v +++ D++ Gki+f++F ++++ FUN_000329-T1 43 DRAIDYHELKVAMRALGFD-VKKVDVLKIMKDYDRESTGKITFDDFNEVMT 92 6789**********99888.99999999******************99987 PP == domain 3 score: 21.9 bits; conditional E-value: 1.3e-07 EF-hand_8 1 ekgvItresLkrilalLglqdlsedevdtlfrefDtDgdGkisf 44 ++g+It++++ + +++ +l + +ev+ fr fD D++Gkis+ FUN_000329-T1 78 STGKITFDDFNEVMTDWMLDRDPQEEVFKAFRLFDDDDSGKISL 121 68**********99887777699999****************96 PP == domain 4 score: 35.5 bits; conditional E-value: 7.4e-12 EF-hand_8 9 sLkrilalLglqdlsedevdtlfrefDtDgdGkisfeeFcvll 51 +L+r ++ Lg + ++++e+++++ efD DgdG i++eeF+ + FUN_000329-T1 123 NLRRVARELGEN-MTDEELRAMIDEFDKDGDGEINEEEFLAIM 164 589989999999.**************************9877 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.2 2.3e-05 0.027 1 22 [. 31 52 .. 31 55 .. 0.91 2 ? 3.8 0.0 0.055 64 14 25 .] 80 91 .. 72 91 .. 0.94 3 ! 15.8 0.4 8.9e-06 0.01 2 24 .. 106 127 .. 105 128 .. 0.84 4 ! 22.2 1.6 8e-08 9.3e-05 1 25 [] 140 164 .. 140 164 .. 0.90 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 2.3e-05 EF-hand_5 1 lkdtFraiDlNgDGkIskeELk 22 +k++F+ +D+++D I+ ELk FUN_000329-T1 31 IKEAFDLFDTDKDRAIDYHELK 52 7889****************98 PP == domain 2 score: 3.8 bits; conditional E-value: 0.055 EF-hand_5 14 GkIskeELkrll 25 GkI+++ +++++ FUN_000329-T1 80 GKITFDDFNEVM 91 9*******9987 PP == domain 3 score: 15.8 bits; conditional E-value: 8.9e-06 EF-hand_5 2 kdtFraiDlNgDGkIskeELkrl 24 k+ Fr +D + +GkIs L+r+ FUN_000329-T1 106 KA-FRLFDDDDSGKISLRNLRRV 127 66.*************8777765 PP == domain 4 score: 22.2 bits; conditional E-value: 8e-08 EF-hand_5 1 lkdtFraiDlNgDGkIskeELkrll 25 l+++ +++D++gDG+I+ eE+ +++ FUN_000329-T1 140 LRAMIDEFDKDGDGEINEEEFLAIM 164 68899****************8765 PP >> EF-hand_9 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.8 7.8e-08 9.1e-05 2 65 .. 33 94 .. 32 95 .. 0.96 2 ! 26.2 0.0 1e-08 1.2e-05 3 63 .. 107 165 .. 106 166 .. 0.95 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 7.8e-08 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaaqdpqeleleelarelDPdgedatveldtFlrVmrdw 65 F+++Dt+k + +l+ +ra + d + +++ + +++D + +++ +d+F Vm dw FUN_000329-T1 33 EAFDLFDTDKDRAIDYHELKVAMRALGF-DVKKVDVLKIMKDYDREST-GKITFDDFNEVMTDW 94 46**************************.*****************99.**************9 PP == domain 2 score: 26.2 bits; conditional E-value: 1e-08 EF-hand_9 3 tFevcDtqktGeVpvskliayLravaaqdpqeleleelarelDPdgedatveldtFlrVmr 63 F+++D + G++ + +l + r + + ++ el e+D dg ++++ ++Fl++m FUN_000329-T1 107 AFRLFDDDDSGKISLRNLRRVARELGE-NMTDEELRAMIDEFDKDGD-GEINEEEFLAIMT 165 4**************************.777889************9.************5 PP >> AIF-1 Allograft inflammatory factor 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 2.4 1.1e-06 0.0013 37 103 .. 25 91 .. 15 96 .. 0.91 2 ! 24.7 0.3 2.7e-08 3.2e-05 41 106 .. 103 167 .. 95 168 .] 0.91 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 1.1e-06 AIF-1 37 eskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmm 103 e++ + +k+ + fd +++ id lk + lG ++++ k++++ ++s+ i++ df ++m FUN_000329-T1 25 EEQKQEIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYDRESTGKITFDDFNEVM 91 4566789999*****************************************************9998 PP == domain 2 score: 24.7 bits; conditional E-value: 2.7e-08 AIF-1 41 eafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmmlGk 106 e+fk + fd +d+G+i l +l+r+ lG + t el+ +i e ++ i+ ++fl +m G+ FUN_000329-T1 103 EVFK-AFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDGDGEINEEEFLAIMTGD 167 5555.5888******************************************************995 PP >> EF-hand_SWAP70_N Switch-associated protein 70-like, N-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.1 0.00072 0.84 4 79 .. 23 97 .. 20 103 .. 0.89 2 ! 10.2 0.0 0.00071 0.82 9 69 .. 101 160 .. 93 165 .. 0.86 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00072 EF-hand_SWAP70_N 4 lreellksiwhaFtaLdveqsgkvsKsqLkVLshnlctvlkiphdeeaLeehfkdddegpvsnqgYmpYlnkfild 79 l ee ++ i aF+ d++++ + LkV l+ +k ++ + + ++ ++ +g ++++++ + + +ld FUN_000329-T1 23 LGEEQKQEIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYDRES-TGKITFDDFNEVMTDWMLD 97 4589999******************************9999999999999999998.9999999999888888887 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00071 EF-hand_SWAP70_N 9 lksiwhaFtaLdveqsgkvsKsqLkVLshnlctvlkiphdeeaLeehfkdddegpvsnqgY 69 ++ ++ aF d+++sgk+s L+ l+ + ++ ++e+ kd +g ++++++ FUN_000329-T1 101 QEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDG-DGEINEEEF 160 56799******************************9999989998888887.788887776 PP >> EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 2.1 0.00035 0.41 27 61 .. 21 55 .. 8 95 .. 0.81 2 ! 9.8 1.5 0.0012 1.4 29 61 .. 132 164 .. 92 167 .. 0.80 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00035 EF-hand_FSTL1 27 lekgksyrellekyFkavDknkdkkldskEllelv 61 e g+++++ +++ F+ +D++kd+++d +El + FUN_000329-T1 21 RELGEEQKQEIKEAFDLFDTDKDRAIDYHELKVAM 55 5567888999********************97655 PP == domain 2 score: 9.8 bits; conditional E-value: 0.0012 EF-hand_FSTL1 29 kgksyrellekyFkavDknkdkkldskEllelv 61 +++ +e l + +++Dk+ d++++++E+l+++ FUN_000329-T1 132 GENMTDEELRAMIDEFDKDGDGEINEEEFLAIM 164 455566778888888888888888888888776 PP >> EH EH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.2 0.3 0.0014 1.6 39 69 .. 28 58 .. 23 75 .. 0.81 2 ? 2.8 0.2 0.13 1.5e+02 13 57 .. 71 119 .. 61 135 .. 0.59 3 ! 10.0 0.4 0.00076 0.88 36 66 .. 134 164 .. 101 165 .. 0.80 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0014 EH 39 qdqLakiWdlaDidddGkLdfeefviamrli 69 ++++++ dl D+d+d +d e +amr FUN_000329-T1 28 KQEIKEAFDLFDTDKDRAIDYHELKVAMRAL 58 56778889********************954 PP == domain 2 score: 2.8 bits; conditional E-value: 0.13 EH 13 fsglkpenk.kltgskvapvLknskLeqd...qLakiWdlaDidddGkL 57 ++ + e+ k+t + + v+ + L++d + k l D dd Gk+ FUN_000329-T1 71 MKDYDRESTgKITFDDFNEVMTDWMLDRDpqeEVFKAFRLFDDDDSGKI 119 4444444444666666666666666654311134444556666666666 PP == domain 3 score: 10.0 bits; conditional E-value: 0.00076 EH 36 kLeqdqLakiWdlaDidddGkLdfeefviam 66 ++ +++L + d D d dG+++ eef ++m FUN_000329-T1 134 NMTDEELRAMIDEFDKDGDGEINEEEFLAIM 164 67899999999****************9998 PP >> EF_EFCAB10_C EFCAB10, C-terminal EF-hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.9 3.8e-05 0.044 2 54 .. 30 90 .. 29 95 .. 0.74 2 ? 4.8 0.1 0.027 31 6 41 .. 107 142 .. 102 165 .. 0.81 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 3.8e-05 EF_EFCAB10_C 2 NldamFemLDptgrGyItlaQYkeALkTLGlstedev.le.......ddgdkItldtFkee 54 +++ F+++D+ + I + k A+ LG + ++ + l+ + + kIt+d F e FUN_000329-T1 30 EIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDvLKimkdydrESTGKITFDDFNEV 90 57899*************************8776654233332221223568******864 PP == domain 2 score: 4.8 bits; conditional E-value: 0.027 EF_EFCAB10_C 6 mFemLDptgrGyItlaQYkeALkTLGlstedevled 41 F+++D + G I+l+ + LG + de+l + FUN_000329-T1 107 AFRLFDDDDSGKISLRNLRRVARELGENMTDEELRA 142 699*************99999999999999998764 PP >> SUB1_ProdP9 SUB1 protease Prodomain ProdP9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 1.1e-05 0.012 33 68 .. 117 151 .. 105 162 .. 0.87 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.1e-05 SUB1_ProdP9 33 GelsnlknlksliielnsdmtdeelaeyikllekkG 68 G++s l+nl+ + el ++mtdeel + i+ ++k G FUN_000329-T1 117 GKIS-LRNLRRVARELGENMTDEELRAMIDEFDKDG 151 6665.9***********************9999887 PP >> Caleosin Caleosin related protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.1 0.0017 2 6 37 .. 31 62 .. 26 70 .. 0.86 2 ? 2.7 0.1 0.13 1.5e+02 97 128 .. 69 100 .. 63 109 .. 0.81 3 ? 2.3 0.0 0.17 2e+02 11 38 .. 109 136 .. 103 144 .. 0.86 4 ? 1.3 0.1 0.35 4.1e+02 9 25 .. 143 159 .. 136 165 .. 0.76 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0017 Caleosin 6 LqqHvaFfDrdkdGiiypldtykgfralgfni 37 +++ + fD+dkd i ++ ++ralgf++ FUN_000329-T1 31 IKEAFDLFDTDKDRAIDYHELKVAMRALGFDV 62 6666788***********************97 PP == domain 2 score: 2.7 bits; conditional E-value: 0.13 Caleosin 97 eiFskyaktekdaltlkellemlkgnrealDl 128 +i + y++++++++t+++++e+++ + D+ FUN_000329-T1 69 KIMKDYDRESTGKITFDDFNEVMTDWMLDRDP 100 57899999999******999999876666665 PP == domain 3 score: 2.3 bits; conditional E-value: 0.17 Caleosin 11 aFfDrdkdGiiypldtykgfralgfnil 38 fD d+ G i + + r+lg n++ FUN_000329-T1 109 RLFDDDDSGKISLRNLRRVARELGENMT 136 569***********99999999998875 PP == domain 4 score: 1.3 bits; conditional E-value: 0.35 Caleosin 9 HvaFfDrdkdGiiypld 25 ++ fD+d+dG i + FUN_000329-T1 143 MIDEFDKDGDGEINEEE 159 56669******997655 PP >> EF-hand_EFHB_C EFHB C-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.1 0.064 75 24 71 .. 47 93 .. 29 96 .. 0.81 2 ? 9.9 0.1 0.00075 0.87 8 69 .. 104 164 .. 101 166 .. 0.88 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.064 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeaskkdpkgevsvesFrnalde 71 + +e++ +++ g+++++ ++ +i k ++++g++ +++F++++++ FUN_000329-T1 47 DYHELKVAMRALGFDVKKVDVLKIMKDYD-RESTGKITFDDFNEVMTD 93 56788888899999999999999999886.789************986 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00075 EF-hand_EFHB_C 8 iftlyGvterdffkpRskeeirrifenigvklsdetFeeiWkeaskkdpkgevsvesFrnal 69 +f + + ++d + s +rr+ ++ g +++de++ ++ +e kd +ge+ e+F ++ FUN_000329-T1 104 VFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFD-KDGDGEINEEEFLAIM 164 67778888888888889999***********************97.8999999999998877 PP >> EF-hand_14 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.2 0.017 20 6 66 .. 35 99 .. 32 107 .. 0.75 2 ? 9.7 0.2 0.0013 1.5 6 49 .. 108 151 .. 102 163 .. 0.89 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.017 EF-hand_14 6 fdlfkdeetdklslakllkaLaetGirkdDPRlaellkklkkaekeks....evesvetleldre 66 fdlf++++ + ++l a+++ G + + +++k ++ k e ++++ ldr+ FUN_000329-T1 35 FDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYDRESTGKItfddFNEVMTDWMLDRD 99 9************************9888887777777777766665544433444445777776 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0013 EF-hand_14 6 fdlfkdeetdklslakllkaLaetGirkdDPRlaellkklkkae 49 f lf+d++++k+sl +l + +e G + +D l+ +++++ k FUN_000329-T1 108 FRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDG 151 899***********************************998765 PP >> FF_PRPF40A PRPF40A-like, FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 3.7 4.2e+03 4 15 .. 26 37 .. 25 56 .. 0.59 2 ? 14.5 2.0 2.9e-05 0.034 5 34 .. 63 92 .. 60 94 .. 0.93 3 ? 1.7 0.1 0.28 3.3e+02 26 36 .. 157 167 .. 138 168 .] 0.85 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 3.7 FF_PRPF40A 4 edkkdikdvlkd 15 e+k ik++ + FUN_000329-T1 26 EQKQEIKEAFDL 37 566667766554 PP == domain 2 score: 14.5 bits; conditional E-value: 2.9e-05 FF_PRPF40A 5 dkkdikdvlkdkkfevtstttfeeFkaais 34 +k d++ ++kd + e t + tf++F ++++ FUN_000329-T1 63 KKVDVLKIMKDYDRESTGKITFDDFNEVMT 92 799*************************97 PP == domain 3 score: 1.7 bits; conditional E-value: 0.28 FF_PRPF40A 26 feeFkaaised 36 eeF+a++++d FUN_000329-T1 157 EEEFLAIMTGD 167 59******998 PP >> UBAP-1_UBA2 Ubiquitin-associated protein 1, UBA2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.4 0.0001 0.12 7 33 .. 19 46 .. 18 48 .. 0.89 2 ? -0.8 0.0 1.7 2e+03 9 22 .. 56 68 .. 51 76 .. 0.74 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.0001 UBAP-1_UBA2 7 kFrEmGFElk.dIKEVLllhnNDQdkAL 33 k rE+G E+k +IKE l++ D d+A+ FUN_000329-T1 19 KRRELGEEQKqEIKEAFDLFDTDKDRAI 46 669******856**************97 PP == domain 2 score: -0.8 bits; conditional E-value: 1.7 UBAP-1_UBA2 9 rEmGFElkdIKEVL 22 r +GF+ k + +VL FUN_000329-T1 56 RALGFDVKKV-DVL 68 7789999876.355 PP >> MgtE_N MgtE intracellular N domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.1 2.2 2.6e+03 89 95 .. 27 33 .. 20 58 .. 0.58 2 ? 14.5 0.2 4.9e-05 0.056 10 64 .. 96 150 .. 90 158 .. 0.92 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 2.2 MgtE_N 89 ereeiee 95 +++ei+e FUN_000329-T1 27 QKQEIKE 33 2222222 PP == domain 2 score: 14.5 bits; conditional E-value: 4.9e-05 MgtE_N 10 leelpeeerlallrllpkeeaaevleeldedvqaeliealsdeelaelleeldsD 64 l++ p+ee + +rl ++++++++ +v+ el e+++deel+++++e d D FUN_000329-T1 96 LDRDPQEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKD 150 666689******************99999**********************9988 PP >> SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.2 0.0017 2 45 78 .. 20 53 .. 9 87 .. 0.84 2 ? 4.8 0.5 0.042 49 35 78 .. 119 162 .. 76 165 .. 0.54 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0017 SPARC_Ca_bdg 45 eekelkeckeaiawkFnklDtnkdklldksELaa 78 ++ +e k+ i+ F+ +Dt+kd+ +d +EL+ FUN_000329-T1 20 RRELGEEQKQEIKEAFDLFDTDKDRAIDYHELKV 53 45667888999999******************85 PP == domain 2 score: 4.8 bits; conditional E-value: 0.042 SPARC_Ca_bdg 35 eeleeeekeaeekelkeckeaiawkFnklDtnkdklldksELaa 78 +l+++++ a e ++++ e + + +++D++ d+ ++++E a FUN_000329-T1 119 ISLRNLRRVARELGENMTDEELRAMIDEFDKDGDGEINEEEFLA 162 34444445555555566666677777777777777777766655 PP >> SurA_N_3 SurA-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.2 0.058 67 66 138 .. 20 91 .. 14 99 .. 0.83 2 ? 8.8 0.1 0.0016 1.8 72 138 .. 99 164 .. 78 167 .. 0.77 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.058 SurA_N_3 66 rqqfgpqldaellkelglrqqvldqlidealllqeakklglavsdeevaqeIasipaFq.edGkFdkerYkalL 138 r+++g++ ++e +++ l + d+ id l+ +++ lg+ v++ v + ++ + + +Gk + + +++++ FUN_000329-T1 20 RRELGEEQKQEIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYD--ReSTGKITFDDFNEVM 91 66788888888888899999999**********************99998877776..4468888888888876 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0016 SurA_N_3 72 qldaellkelglrqqvldqlidealllqeakklglavsdeevaqeIasipaFq.edGkFdkerYkalL 138 + ++e +k++ l ++ ++ i+ + l+ a++lg +++dee++++I + + + dG+ ++e + a++ FUN_000329-T1 99 DPQEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFD--KdGDGEINEEEFLAIM 164 55666777777777777788999999********************9887..5459999999998876 PP >> SRI SRI (Set2 Rpb1 interacting) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.41 4.8e+02 51 65 .. 19 34 .. 6 39 .. 0.76 2 ? 0.6 0.0 0.86 1e+03 8 27 .. 67 87 .. 65 92 .. 0.85 3 ? 6.9 0.0 0.0091 11 18 45 .. 114 142 .. 102 160 .. 0.84 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.41 SRI 51 p.lelseevkkkvkkf 65 + el ee+k+++k+ FUN_000329-T1 19 KrRELGEEQKQEIKEA 34 257899********85 PP == domain 2 score: 0.6 bits; conditional E-value: 0.86 SRI 8 VvkvltpYykk..gkiaskelf 27 V k+++ Y ++ gki + ++f FUN_000329-T1 67 VLKIMKDYDREstGKI-TFDDF 87 7799999*99999999.77777 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0091 SRI 18 k..gkiaskelfKklarelthklvekelkk 45 + gki s ++ ++arel +++++ el+ FUN_000329-T1 114 DdsGKI-SLRNLRRVARELGENMTDEELRA 142 45599*.999***************99985 PP >> BAHCC1-like_Tudor BAHCC1-like, Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 8.5 9.9e+03 42 50 .. 78 86 .. 68 88 .. 0.58 2 ? 10.4 0.1 0.00056 0.66 48 62 .. 111 125 .. 98 131 .. 0.90 3 ? -2.9 0.2 8.3 9.6e+03 47 52 .. 146 152 .. 133 156 .. 0.60 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 8.5 BAHCC1-like_Tudor 42 klvaVefDD 50 ++ ++ fDD FUN_000329-T1 78 STGKITFDD 86 333556666 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00056 BAHCC1-like_Tudor 48 fDDGDsgriplediR 62 fDD Dsg+i+l+++R FUN_000329-T1 111 FDDDDSGKISLRNLR 125 9************99 PP == domain 3 score: -2.9 bits; conditional E-value: 8.3 BAHCC1-like_Tudor 47 efD.DGD 52 efD DGD FUN_000329-T1 146 EFDkDGD 152 7885665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1534 (0.0600509); expected 510.9 (0.02) Passed bias filter: 1046 (0.0409473); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 22 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 1626.18 // Query: FUN_000329-T2 [L=165] Description: FUN_000329 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-25 90.0 15.9 1.8e-13 51.1 4.6 2.1 2 EF-hand_7 EF-hand domain pair 1.8e-21 74.5 18.8 1.2e-07 31.3 0.3 4.2 4 EF-hand_1 EF hand domain 1e-19 68.8 14.1 1.1e-07 31.5 0.2 4.3 4 EF-hand_6 EF-hand domain 2.9e-12 46.6 17.3 0.00015 21.9 1.9 4.1 4 EF-hand_8 EF-hand domain pair 5.9e-10 38.7 12.1 0.01 15.8 0.4 4.5 4 EF-hand_5 EF hand 1.1e-09 39.1 2.2 8.7e-05 23.4 0.8 2.1 2 EF-hand_9 EF-hand domain 3.9e-08 34.1 6.2 0.0013 19.5 2.5 2.1 2 AIF-1 Allograft inflammatory factor 1 0.0007 19.7 2.2 0.042 14.0 0.9 2.6 2 EF_EFCAB10_C EFCAB10, C-terminal EF-hand 0.0012 19.4 0.1 0.8 10.3 0.1 2.1 2 EF-hand_SWAP70_N Switch-associated protein 70-like, N-termi 0.0081 16.4 0.0 0.017 15.4 0.0 1.5 1 SUB1_ProdP9 SUB1 protease Prodomain ProdP9 ------ inclusion threshold ------ 0.019 15.4 2.3 1.8 8.9 0.1 3.2 4 Caleosin Caleosin related protein 0.025 15.4 2.6 1.6 9.6 0.2 2.2 2 EF-hand_14 EF-hand domain 0.033 14.5 2.0 0.033 14.5 2.0 2.3 2 FF_PRPF40A PRPF40A-like, FF domain 0.037 14.3 1.5 0.12 12.8 0.4 2.2 2 UBAP-1_UBA2 Ubiquitin-associated protein 1, UBA2 domai 0.039 15.0 2.0 0.066 14.2 0.1 2.1 2 MgtE_N MgtE intracellular N domain 0.055 14.3 7.0 0.36 11.7 1.9 3.1 2 EF-hand_FSTL1 Follistatin-related protein 1, EF-hand dom 0.084 13.3 2.6 1.4 9.4 0.2 2.6 2 EH EH domain 0.21 12.4 0.9 13 6.7 0.0 2.9 3 SRI SRI (Set2 Rpb1 interacting) domain 0.64 10.5 0.1 0.64 10.5 0.1 2.0 2 BAHCC1-like_Tudor BAHCC1-like, Tudor domain Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.1 4.6 1.4e-16 1.8e-13 2 67 .] 29 92 .. 28 92 .. 0.96 2 ! 45.0 3.5 1.1e-14 1.5e-11 2 55 .. 102 153 .. 101 154 .. 0.96 Alignments for each domain: == domain 1 score: 51.1 bits; conditional E-value: 1.4e-16 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlelys 67 +++keaF+l+D+d+d +d+ elk ++r +g+++++ +v +++k+ D + G+i+f++F e+++ FUN_000329-T2 29 QEIKEAFDLFDTDKDRAIDYHELKVAMR--ALGFDVKKVDVLKIMKDYDRESTGKITFDDFNEVMT 92 79**********************9999..9*******************************9985 PP == domain 2 score: 45.0 bits; conditional E-value: 1.1e-14 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdG 55 e+ ++aF+l+D d++G+++ l+++ r e+ge+++dee++++++efD+d+dG FUN_000329-T2 102 EEVFKAFRLFDDDDSGKISLRNLRRVAR--ELGENMTDEELRAMIDEFDKDGDG 153 67789***********************..***********************9 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.3 8.6e-11 1.2e-07 1 29 [] 30 58 .. 30 58 .. 0.96 2 ! 20.2 1.3 2.9e-07 0.00039 2 27 .. 67 92 .. 66 93 .. 0.92 3 ! 18.5 0.1 1e-06 0.0014 1 28 [. 103 130 .. 103 131 .. 0.89 4 ! 15.9 0.8 7.2e-06 0.0097 1 15 [. 139 153 .. 139 154 .. 0.94 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 8.6e-11 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkkl 29 e+ke+F++fD+D+d Id+ E+k ++++l FUN_000329-T2 30 EIKEAFDLFDTDKDRAIDYHELKVAMRAL 58 79************************975 PP == domain 2 score: 20.2 bits; conditional E-value: 2.9e-07 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellk 27 + +i++ +D+ GkI+f++f e+++ FUN_000329-T2 67 VLKIMKDYDRESTGKITFDDFNEVMT 92 679*********************97 PP == domain 3 score: 18.5 bits; conditional E-value: 1e-06 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkk 28 e+ ++Fr+fD D +GkI++ ++++ ++ FUN_000329-T2 103 EVFKAFRLFDDDDSGKISLRNLRRVARE 130 6789***************999998765 PP == domain 4 score: 15.9 bits; conditional E-value: 7.2e-06 EF-hand_1 1 elkeiFrefDkDgdG 15 el+ +++efDkDgdG FUN_000329-T2 139 ELRAMIDEFDKDGDG 153 799************ PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.5 0.2 7.9e-11 1.1e-07 1 30 [] 30 59 .. 30 59 .. 0.97 2 ! 14.5 0.4 2.3e-05 0.031 4 27 .. 69 92 .. 66 97 .. 0.87 3 ! 22.6 0.3 5.7e-08 7.7e-05 3 30 .] 105 132 .. 103 132 .. 0.92 4 ! 8.4 0.2 0.0021 2.9 1 15 [. 139 153 .. 139 154 .. 0.89 Alignments for each domain: == domain 1 score: 31.5 bits; conditional E-value: 7.9e-11 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrslG 30 e++eaF+lfD+d+d i+++El+ a+r+lG FUN_000329-T2 30 EIKEAFDLFDTDKDRAIDYHELKVAMRALG 59 69*************************998 PP == domain 2 score: 14.5 bits; conditional E-value: 2.3e-05 EF-hand_6 4 eaFklfDkdgdGyisleElraalr 27 ++ k +D++ +G+i+++++ ++++ FUN_000329-T2 69 KIMKDYDRESTGKITFDDFNEVMT 92 67899**************99997 PP == domain 3 score: 22.6 bits; conditional E-value: 5.7e-08 EF-hand_6 3 reaFklfDkdgdGyisleElraalrslG 30 +aF+lfD d++G+isl lr++ r lG FUN_000329-T2 105 FKAFRLFDDDDSGKISLRNLRRVARELG 132 68*********************99987 PP == domain 4 score: 8.4 bits; conditional E-value: 0.0021 EF-hand_6 1 elreaFklfDkdgdG 15 elr + + fDkdgdG FUN_000329-T2 139 ELRAMIDEFDKDGDG 153 6889999*******9 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.6 0.0015 2 24 51 .. 28 55 .. 17 55 .. 0.87 2 ! 17.7 1.2 2.4e-06 0.0032 2 52 .. 43 92 .. 42 94 .. 0.92 3 ! 21.9 1.9 1.1e-07 0.00015 1 44 [. 78 121 .. 78 123 .. 0.91 4 ! 21.2 0.2 1.8e-07 0.00025 9 40 .. 123 153 .. 122 154 .. 0.94 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0015 EF-hand_8 24 edevdtlfrefDtDgdGkisfeeFcvll 51 ++e+ + f fDtD+d +i+ e++v++ FUN_000329-T2 28 KQEIKEAFDLFDTDKDRAIDYHELKVAM 55 89**************999988888776 PP == domain 2 score: 17.7 bits; conditional E-value: 2.4e-06 EF-hand_8 2 kgvItresLkrilalLglqdlsedevdtlfrefDtDgdGkisfeeFcvlle 52 + I+ ++Lk ++++Lg +++ +v +++ D++ Gki+f++F ++++ FUN_000329-T2 43 DRAIDYHELKVAMRALGFD-VKKVDVLKIMKDYDRESTGKITFDDFNEVMT 92 6789**********99888.99999999******************99987 PP == domain 3 score: 21.9 bits; conditional E-value: 1.1e-07 EF-hand_8 1 ekgvItresLkrilalLglqdlsedevdtlfrefDtDgdGkisf 44 ++g+It++++ + +++ +l + +ev+ fr fD D++Gkis+ FUN_000329-T2 78 STGKITFDDFNEVMTDWMLDRDPQEEVFKAFRLFDDDDSGKISL 121 68**********99887777699999****************96 PP == domain 4 score: 21.2 bits; conditional E-value: 1.8e-07 EF-hand_8 9 sLkrilalLglqdlsedevdtlfrefDtDgdG 40 +L+r ++ Lg + ++++e+++++ efD DgdG FUN_000329-T2 123 NLRRVARELGEN-MTDEELRAMIDEFDKDGDG 153 589999999***.******************9 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.2 1.9e-05 0.026 1 22 [. 31 52 .. 31 55 .. 0.91 2 ? 3.8 0.0 0.047 63 14 25 .] 80 91 .. 72 91 .. 0.94 3 ! 15.8 0.4 7.5e-06 0.01 2 24 .. 106 127 .. 105 128 .. 0.84 4 ! 10.2 0.5 0.00045 0.61 1 14 [. 140 153 .. 140 154 .. 0.90 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.9e-05 EF-hand_5 1 lkdtFraiDlNgDGkIskeELk 22 +k++F+ +D+++D I+ ELk FUN_000329-T2 31 IKEAFDLFDTDKDRAIDYHELK 52 7889****************98 PP == domain 2 score: 3.8 bits; conditional E-value: 0.047 EF-hand_5 14 GkIskeELkrll 25 GkI+++ +++++ FUN_000329-T2 80 GKITFDDFNEVM 91 9*******9987 PP == domain 3 score: 15.8 bits; conditional E-value: 7.5e-06 EF-hand_5 2 kdtFraiDlNgDGkIskeELkrl 24 k+ Fr +D + +GkIs L+r+ FUN_000329-T2 106 KA-FRLFDDDDSGKISLRNLRRV 127 66.*************8777765 PP == domain 4 score: 10.2 bits; conditional E-value: 0.00045 EF-hand_5 1 lkdtFraiDlNgDG 14 l+++ +++D++gDG FUN_000329-T2 140 LRAMIDEFDKDGDG 153 68899********* PP >> EF-hand_9 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.8 6.5e-08 8.7e-05 2 65 .. 33 94 .. 32 95 .. 0.96 2 ! 15.2 0.0 2.3e-05 0.031 3 49 .. 107 152 .. 106 159 .. 0.89 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 6.5e-08 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaaqdpqeleleelarelDPdgedatveldtFlrVmrdw 65 F+++Dt+k + +l+ +ra + d + +++ + +++D + +++ +d+F Vm dw FUN_000329-T2 33 EAFDLFDTDKDRAIDYHELKVAMRALGF-DVKKVDVLKIMKDYDREST-GKITFDDFNEVMTDW 94 46**************************.*****************99.**************9 PP == domain 2 score: 15.2 bits; conditional E-value: 2.3e-05 EF-hand_9 3 tFevcDtqktGeVpvskliayLravaaqdpqeleleelarelDPdge 49 F+++D + G++ + +l + r + + ++ el e+D dg FUN_000329-T2 107 AFRLFDDDDSGKISLRNLRRVARELGE-NMTDEELRAMIDEFDKDGD 152 4**************************.677889*********9998 PP >> AIF-1 Allograft inflammatory factor 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 2.5 9.6e-07 0.0013 37 103 .. 25 91 .. 15 97 .. 0.91 2 ! 16.5 0.1 7.8e-06 0.011 41 88 .. 103 149 .. 95 158 .. 0.86 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 9.6e-07 AIF-1 37 eskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmm 103 e++ + +k+ + fd +++ id lk + lG ++++ k++++ ++s+ i++ df ++m FUN_000329-T2 25 EEQKQEIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYDRESTGKITFDDFNEVM 91 4566789999*****************************************************9998 PP == domain 2 score: 16.5 bits; conditional E-value: 7.8e-06 AIF-1 41 eafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtg 88 e+fk + fd +d+G+i l +l+r+ lG + t el+ +i e + FUN_000329-T2 103 EVFK-AFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDK 149 5555.5888**********************************99754 PP >> EF_EFCAB10_C EFCAB10, C-terminal EF-hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.9 3.1e-05 0.042 2 54 .. 30 90 .. 29 95 .. 0.74 2 ? 4.3 0.0 0.034 46 6 41 .. 107 142 .. 102 150 .. 0.85 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 3.1e-05 EF_EFCAB10_C 2 NldamFemLDptgrGyItlaQYkeALkTLGlstedev.le.......ddgdkItldtFkee 54 +++ F+++D+ + I + k A+ LG + ++ + l+ + + kIt+d F e FUN_000329-T2 30 EIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDvLKimkdydrESTGKITFDDFNEV 90 57899*************************8776654233332221223568******864 PP == domain 2 score: 4.3 bits; conditional E-value: 0.034 EF_EFCAB10_C 6 mFemLDptgrGyItlaQYkeALkTLGlstedevled 41 F+++D + G I+l+ + LG + de+l + FUN_000329-T2 107 AFRLFDDDDSGKISLRNLRRVARELGENMTDEELRA 142 69**************99999999999999998865 PP >> EF-hand_SWAP70_N Switch-associated protein 70-like, N-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.1 0.0006 0.8 4 79 .. 23 97 .. 20 103 .. 0.89 2 ! 8.0 0.0 0.003 4.1 9 60 .. 101 152 .. 93 156 .. 0.84 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0006 EF-hand_SWAP70_N 4 lreellksiwhaFtaLdveqsgkvsKsqLkVLshnlctvlkiphdeeaLeehfkdddegpvsnqgYmpYlnkfild 79 l ee ++ i aF+ d++++ + LkV l+ +k ++ + + ++ ++ +g ++++++ + + +ld FUN_000329-T2 23 LGEEQKQEIKEAFDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYDRES-TGKITFDDFNEVMTDWMLD 97 4589999******************************9999999999999999998.9999999999888888887 PP == domain 2 score: 8.0 bits; conditional E-value: 0.003 EF-hand_SWAP70_N 9 lksiwhaFtaLdveqsgkvsKsqLkVLshnlctvlkiphdeeaLeehfkddd 60 ++ ++ aF d+++sgk+s L+ l+ + ++ ++e+ kd d FUN_000329-T2 101 QEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDGD 152 56799****************9999999999999988888888888888775 PP >> SUB1_ProdP9 SUB1 protease Prodomain ProdP9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 1.2e-05 0.017 33 68 .. 117 151 .. 105 156 .. 0.89 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.2e-05 SUB1_ProdP9 33 GelsnlknlksliielnsdmtdeelaeyikllekkG 68 G++s l+nl+ + el ++mtdeel + i+ ++k G FUN_000329-T2 117 GKIS-LRNLRRVARELGENMTDEELRAMIDEFDKDG 151 6665.9***********************9988877 PP >> Caleosin Caleosin related protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.1 0.0014 1.8 6 37 .. 31 62 .. 26 71 .. 0.85 2 ? 2.7 0.1 0.11 1.5e+02 97 128 .. 69 100 .. 63 109 .. 0.81 3 ? 2.5 0.0 0.13 1.8e+02 11 38 .. 109 136 .. 101 144 .. 0.85 4 ? -2.3 0.0 3.9 5.3e+03 8 19 .. 142 153 .. 135 154 .. 0.73 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0014 Caleosin 6 LqqHvaFfDrdkdGiiypldtykgfralgfni 37 +++ + fD+dkd i ++ ++ralgf++ FUN_000329-T2 31 IKEAFDLFDTDKDRAIDYHELKVAMRALGFDV 62 6666788***********************97 PP == domain 2 score: 2.7 bits; conditional E-value: 0.11 Caleosin 97 eiFskyaktekdaltlkellemlkgnrealDl 128 +i + y++++++++t+++++e+++ + D+ FUN_000329-T2 69 KIMKDYDRESTGKITFDDFNEVMTDWMLDRDP 100 57899999999******999999876666665 PP == domain 3 score: 2.5 bits; conditional E-value: 0.13 Caleosin 11 aFfDrdkdGiiypldtykgfralgfnil 38 fD d+ G i + + r+lg n++ FUN_000329-T2 109 RLFDDDDSGKISLRNLRRVARELGENMT 136 569**********999999999998875 PP == domain 4 score: -2.3 bits; conditional E-value: 3.9 Caleosin 8 qHvaFfDrdkdG 19 ++ fD+d+dG FUN_000329-T2 142 AMIDEFDKDGDG 153 556669999998 PP >> EF-hand_14 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.2 0.014 19 6 66 .. 35 99 .. 32 107 .. 0.75 2 ? 9.6 0.2 0.0012 1.6 6 49 .. 108 151 .. 102 160 .. 0.91 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.014 EF-hand_14 6 fdlfkdeetdklslakllkaLaetGirkdDPRlaellkklkkaekeks....evesvetleldre 66 fdlf++++ + ++l a+++ G + + +++k ++ k e ++++ ldr+ FUN_000329-T2 35 FDLFDTDKDRAIDYHELKVAMRALGFDVKKVDVLKIMKDYDRESTGKItfddFNEVMTDWMLDRD 99 9************************9888887777777777766665544433444445777776 PP == domain 2 score: 9.6 bits; conditional E-value: 0.0012 EF-hand_14 6 fdlfkdeetdklslakllkaLaetGirkdDPRlaellkklkkae 49 f lf+d++++k+sl +l + +e G + +D l+ +++++ k FUN_000329-T2 108 FRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDG 151 899**********************************9998765 PP >> FF_PRPF40A PRPF40A-like, FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.1 3.1 4.1e+03 4 15 .. 26 37 .. 25 56 .. 0.59 2 ? 14.5 2.0 2.4e-05 0.033 5 34 .. 63 92 .. 60 94 .. 0.93 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 3.1 FF_PRPF40A 4 edkkdikdvlkd 15 e+k ik++ + FUN_000329-T2 26 EQKQEIKEAFDL 37 566667766554 PP == domain 2 score: 14.5 bits; conditional E-value: 2.4e-05 FF_PRPF40A 5 dkkdikdvlkdkkfevtstttfeeFkaais 34 +k d++ ++kd + e t + tf++F ++++ FUN_000329-T2 63 KKVDVLKIMKDYDRESTGKITFDDFNEVMT 92 799*************************97 PP >> UBAP-1_UBA2 Ubiquitin-associated protein 1, UBA2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.4 8.6e-05 0.12 7 33 .. 19 46 .. 18 48 .. 0.89 2 ? -0.8 0.0 1.5 2e+03 9 22 .. 56 68 .. 51 76 .. 0.74 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 8.6e-05 UBAP-1_UBA2 7 kFrEmGFElk.dIKEVLllhnNDQdkAL 33 k rE+G E+k +IKE l++ D d+A+ FUN_000329-T2 19 KRRELGEEQKqEIKEAFDLFDTDKDRAI 46 669******856**************97 PP == domain 2 score: -0.8 bits; conditional E-value: 1.5 UBAP-1_UBA2 9 rEmGFElkdIKEVL 22 r +GF+ k + +VL FUN_000329-T2 56 RALGFDVKKV-DVL 68 7789999876.355 PP >> MgtE_N MgtE intracellular N domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.1 1.9 2.5e+03 89 95 .. 27 33 .. 20 58 .. 0.58 2 ? 14.2 0.1 4.9e-05 0.066 10 64 .. 96 150 .. 90 151 .. 0.93 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.9 MgtE_N 89 ereeiee 95 +++ei+e FUN_000329-T2 27 QKQEIKE 33 2222222 PP == domain 2 score: 14.2 bits; conditional E-value: 4.9e-05 MgtE_N 10 leelpeeerlallrllpkeeaaevleeldedvqaeliealsdeelaelleeldsD 64 l++ p+ee + +rl ++++++++ +v+ el e+++deel+++++e d D FUN_000329-T2 96 LDRDPQEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKD 150 666689******************99999**********************9987 PP >> EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 1.9 0.00027 0.36 27 61 .. 21 55 .. 8 95 .. 0.81 2 ? 3.1 0.3 0.13 1.7e+02 34 62 .. 101 129 .. 93 157 .. 0.74 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00027 EF-hand_FSTL1 27 lekgksyrellekyFkavDknkdkkldskEllelv 61 e g+++++ +++ F+ +D++kd+++d +El + FUN_000329-T2 21 RELGEEQKQEIKEAFDLFDTDKDRAIDYHELKVAM 55 5567888999********************97655 PP == domain 2 score: 3.1 bits; conditional E-value: 0.13 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllelve 62 +e ++k F+ +D++ +k++ l ++ + FUN_000329-T2 101 QEEVFKAFRLFDDDDSGKISLRNLRRVAR 129 67788999999999999999988888776 PP >> EH EH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.2 0.001 1.4 39 69 .. 28 58 .. 23 76 .. 0.80 2 ? 3.7 0.4 0.061 82 14 62 .. 72 124 .. 64 155 .. 0.61 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.001 EH 39 qdqLakiWdlaDidddGkLdfeefviamrli 69 ++++++ dl D+d+d +d e +amr FUN_000329-T2 28 KQEIKEAFDLFDTDKDRAIDYHELKVAMRAL 58 56778889********************954 PP == domain 2 score: 3.7 bits; conditional E-value: 0.061 EH 14 sglkpenk.kltgskvapvLknskLe...qdqLakiWdlaDidddGkLdfeef 62 + + e+ k+t + + v+ + L+ q++ k l D dd Gk+ + FUN_000329-T2 72 KDYDRESTgKITFDDFNEVMTDWMLDrdpQEEVFKAFRLFDDDDSGKISLRNL 124 44555555577777777777777776111344455566788888888876554 PP >> SRI SRI (Set2 Rpb1 interacting) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.1 0.34 4.6e+02 51 65 .. 19 34 .. 6 39 .. 0.76 2 ? 0.7 0.0 0.72 9.7e+02 8 27 .. 67 87 .. 65 92 .. 0.85 3 ? 6.7 0.0 0.0094 13 18 44 .. 114 141 .. 102 150 .. 0.84 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.34 SRI 51 p.lelseevkkkvkkf 65 + el ee+k+++k+ FUN_000329-T2 19 KrRELGEEQKQEIKEA 34 257899********85 PP == domain 2 score: 0.7 bits; conditional E-value: 0.72 SRI 8 VvkvltpYykk..gkiaskelf 27 V k+++ Y ++ gki + ++f FUN_000329-T2 67 VLKIMKDYDREstGKI-TFDDF 87 7799999*99999999.77777 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0094 SRI 18 k..gkiaskelfKklarelthklvekelk 44 + gki s ++ ++arel +++++ el+ FUN_000329-T2 114 DdsGKI-SLRNLRRVARELGENMTDEELR 141 45599*.999***************9997 PP >> BAHCC1-like_Tudor BAHCC1-like, Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 7.2 9.7e+03 42 50 .. 78 86 .. 68 88 .. 0.58 2 ? 10.5 0.1 0.00047 0.64 48 62 .. 111 125 .. 98 131 .. 0.90 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 7.2 BAHCC1-like_Tudor 42 klvaVefDD 50 ++ ++ fDD FUN_000329-T2 78 STGKITFDD 86 333556666 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00047 BAHCC1-like_Tudor 48 fDDGDsgriplediR 62 fDD Dsg+i+l+++R FUN_000329-T2 111 FDDDDSGKISLRNLR 125 9************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (165 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1446 (0.056606); expected 510.9 (0.02) Passed bias filter: 1033 (0.0404384); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 19 [number of targets reported over threshold] # CPU time: 0.30u 0.43s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 1635.77 // Query: FUN_000330-T1 [L=2564] Description: FUN_000330 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-134 440.1 174.7 2.9e-38 130.9 12.6 16.8 15 Talin_IBS2B Talin IBS2B domain 1.7e-93 311.7 151.6 4.9e-62 209.4 6.0 15.9 13 TLN1-like_RS Talin 1-like, rod segment domain 1.8e-71 239.6 195.1 8.9e-48 162.7 12.1 19.6 19 I_LWEQ I/LWEQ domain 1.1e-67 226.5 154.0 7.5e-39 133.3 9.6 14.7 13 Talin_R4 Talin, R4 domain 2.5e-57 193.9 4.1 2.5e-57 193.9 4.1 14.2 13 Talin_middle Talin, middle domain 1.3e-39 135.7 12.0 1.3e-39 135.7 12.0 17.0 20 Talin_VBS2 Talin VBS2 domain 1.2e-32 112.2 0.0 2.6e-32 111.2 0.0 1.6 1 IRS PTB domain (IRS-1 type) 2.5e-32 112.3 38.3 6.8e-29 101.2 0.0 8.5 7 VBS Vinculin Binding Site 1.1e-30 106.3 0.0 3.9e-28 98.1 0.0 2.9 2 FERM_f0 N-terminal or F0 domain of Talin-head FERM 2e-26 93.1 1.1 7.6e-26 91.2 0.1 2.8 1 FERM_M FERM central domain 7e-08 32.7 2.9 2.3e-06 27.9 0.2 3.5 3 FERM_N FERM N-terminal domain 2e-06 28.2 0.2 5.1e-05 23.7 0.1 3.0 2 RA_2 RA like domain 4.9e-05 22.3 100.7 0.00022 20.2 1.9 9.2 8 Vinculin Vinculin family 0.00087 19.6 0.7 4.4 7.8 0.1 4.6 3 DUF1657 Protein of unknown function (DUF1657) 0.0063 17.5 0.9 0.02 15.8 0.1 2.2 2 DdMyo7_FERM DdMyo7 FERM domain ------ inclusion threshold ------ 0.013 16.0 0.1 1 9.9 0.1 3.0 2 TrcR Transcriptional cell cycle regulator TrcR 0.02 15.3 0.1 0.074 13.5 0.0 2.0 1 PUB PUB domain 0.052 14.0 55.3 0.087 13.3 0.1 11.4 13 DUF7783 Domain of unknown function (DUF7783) 0.24 11.2 16.8 0.17 11.7 1.3 3.5 3 URGCP Up-regulator of cell proliferation-like domain 3.2 8.2 38.7 9.6 6.6 0.2 10.8 10 Serine_rich Serine rich protein interaction domain Domain annotation for each model (and alignments): >> Talin_IBS2B Talin IBS2B domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 1.8e-06 0.0023 5 114 .. 518 677 .. 515 681 .. 0.85 2 ! 33.2 13.6 4.3e-11 5.5e-08 24 113 .. 685 775 .. 675 780 .. 0.94 3 ? -2.2 0.0 4.2 5.3e+03 29 50 .. 790 811 .. 787 820 .. 0.80 4 ! 38.9 10.1 7.7e-13 9.8e-10 5 110 .. 821 927 .. 816 935 .. 0.94 5 ! 14.9 4.3 2.1e-05 0.027 22 116 .. 967 1062 .. 939 1064 .. 0.86 6 ! 104.7 3.4 3e-33 3.8e-30 1 118 [] 1068 1229 .. 1068 1229 .. 0.99 7 ! 23.5 7.2 4.4e-08 5.6e-05 17 117 .. 1277 1378 .. 1230 1380 .. 0.84 8 ? -1.3 0.0 2.2 2.8e+03 2 52 .. 1382 1434 .. 1381 1467 .. 0.76 9 ! 130.9 12.6 2.3e-41 2.9e-38 1 118 [] 1485 1602 .. 1485 1602 .. 0.99 10 ! 9.8 0.3 0.0008 1 58 116 .. 1616 1675 .. 1609 1677 .. 0.86 11 ! 26.9 1.5 4e-09 5.1e-06 2 115 .. 1680 1836 .. 1679 1839 .. 0.95 12 ? 5.9 0.0 0.013 16 6 116 .. 1886 1998 .. 1881 2001 .. 0.80 13 ! 29.6 6.5 5.8e-10 7.4e-07 7 117 .. 2050 2164 .. 2042 2165 .. 0.83 14 ! 47.7 6.1 1.4e-15 1.8e-12 2 116 .. 2172 2317 .. 2171 2318 .. 0.98 15 ! 12.4 21.9 0.00012 0.16 5 116 .. 2373 2504 .. 2333 2506 .. 0.84 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.8e-06 Talin_IBS2B 5 eldsaleaikqaceeLaepek..................................................nqqqvlsaAtdiakalsaLcnacrg 50 l++ l++i++a++eL +p + n +++a + i+++l++L + ++ FUN_000330-T1 518 SLSQGLNTIDSAEKELGSPTQvpalgsdpaslkwkqntldvskqkvasrlaalsascasivtltsgepeetNYTAAGAAINTISSNLQDLSKGIKM 613 67788899999999999999999999999999999999999999999999999999999999999***9877778888889*************** PP Talin_IBS2B 51 asakts.npeakrkfvqsAkdVanktaaLvkeikallqnpspenrqrlaqaakplleavenlvaf 114 ++ + + ++ + ++++A++ a + ++L+k +++ s e+r rl +aa ++ ++ +l +f FUN_000330-T1 614 IAGLLDdDDDTSKSLLDAARNLAGAFSNLLKAAQEGGGADS-ESRGRLLSAAGNVGSSGASLLQF 677 **99998899999*******************999766655.67777777777777776666666 PP == domain 2 score: 33.2 bits; conditional E-value: 4.3e-11 Talin_IBS2B 24 eknqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaqaakplleavenlva 113 +++q+ l+ A+++a+a++aL+ +++++++ ++ e ++k++++Ak+ a +ta+Lv +k ++ + s+ ++++ +aak +++av+ + + FUN_000330-T1 685 QRTQEMLLALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVACVKVVVPSIsSHMCQEQVVEAAKLVATAVDDTES 775 5689999999*******************************************************9899*****************98766 PP == domain 3 score: -2.2 bits; conditional E-value: 4.2 Talin_IBS2B 29 qvlsaAtdiakalsaLcnacrg 50 +++ aA+ ++ al++L+ +r+ FUN_000330-T1 790 EMMTAAQGVRDALNNLLIKVRE 811 5788888888888888888886 PP == domain 4 score: 38.9 bits; conditional E-value: 7.7e-13 Talin_IBS2B 5 eldsaleaikqaceeLaepeknqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaq 99 + d++ + i a+++L ++ n ++ + A+ a+a s+L++ ++ +++ ++++++++++ +Ak a++ta+Lv+ +k +++np + +q+l+q FUN_000330-T1 821 QYDETCDDILGATDRLFNSMGNAGEMVKQAKILAQASSSLVTGIKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKGAAKNPnAADQQQKLKQ 916 66888999999999999999*****************************************************************888******** PP Talin_IBS2B 100 aakplleaven 110 aa++l +a ++ FUN_000330-T1 917 AAEDLRSATNA 927 ******99876 PP == domain 5 score: 14.9 bits; conditional E-value: 2.1e-05 Talin_IBS2B 22 epeknqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaqaakplleavenlvaf 114 +++++qqq + + +++++L+++ ++ +++ + + +++++ k+ ++ t++Lv + ka+l +p ++la+ ak+ ++++ +l ++ FUN_000330-T1 967 RNQTSQQQLDDQCKPVEESINHLVESLKETGRNPDVAAPQLALINTSKEFIQPTSKLVANSKAALPTIgDPITATQLANFAKSTATSLAELREA 1060 334499999999999****************************************************99*******************999887 PP Talin_IBS2B 115 ap 116 a+ FUN_000330-T1 1061 AE 1062 75 PP == domain 6 score: 104.7 bits; conditional E-value: 3e-33 Talin_IBS2B 1 idqseldsaleaikqaceeLaepek...........................................nqqqvlsaAtdiakalsaLcnacrga 51 ++++e+dsal+++++++ +L++ ek n+++++ aA+d+a+al+ L+ a+rg+ FUN_000330-T1 1068 CGTLEIDSALDTVDSLNSDLKAYEKsaaegkliplpgetaescglelgatsktvgssmaqlltaasqgNESYTGIAARDTANALQVLTAAARGV 1161 899******************************************************************************************* PP Talin_IBS2B 52 saktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaqaakplleavenlvafapsp 118 +a+ ++++ + +++++++dV++++a+L++e+k++++np +p n+ rlaqaak++++a++n+v+f+p++ FUN_000330-T1 1162 AATADDKALQLNLIKATQDVVAESAKLINEAKSAVNNPgDPGNQPRLAQAAKEVSQALNNCVNFLPGQ 1229 ******************************************************************98 PP == domain 7 score: 23.5 bits; conditional E-value: 4.4e-08 Talin_IBS2B 17 ceeLaepeknqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaqaakplleave 109 e +++++ + +q ++ ++ +++ ++L+ + + + + ++++ak +v+ k+ +++++L+ +k+l+++p p+++++la+aa++++++++ FUN_000330-T1 1277 SEMVSASRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAKDEAAKDSMVRNLKNTSTASSKLLLAAKSLVSDPnAPNAKNSLANAARAVTDSIN 1370 2333444449999************************************************************999****************** PP Talin_IBS2B 110 nlvafaps 117 l ++ +s FUN_000330-T1 1371 MLLNACMS 1378 *9987765 PP == domain 8 score: -1.3 bits; conditional E-value: 2.2 Talin_IBS2B 2 dqseldsaleaikqaceeLaepek..nqqqvlsaAtdiakalsaLcnacrgas 52 +q+e+d+al i+++ + L++p + n++ + +++++ ++L++a +s FUN_000330-T1 1382 GQKECDNALRNIQAVSNILDNPVEpvNNDTFFDCLDKVTRQSHDLTEALPRIS 1434 68999999999999999999988777555566666666666666666654444 PP == domain 9 score: 130.9 bits; conditional E-value: 2.3e-41 Talin_IBS2B 1 idqseldsaleaikqaceeLaepeknqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnpspenr 94 idq+++ ++ ++i +ac++L +pe++qqqvl aAt++ak++saLcnac++asakt+np+akr+fvq+AkdVan+ta+Lvk+ k l+ ++s++nr FUN_000330-T1 1485 IDQAQFLNSKQEIMDACQSLLNPEATQQQVLGAATAVAKHTSALCNACKAASAKTNNPAAKRQFVQAAKDVANNTANLVKNTKILAGDMSEANR 1578 79******************************************************************************************** PP Talin_IBS2B 95 qrlaqaakplleavenlvafapsp 118 +++a+a++pl+++ve+l+a+a sp FUN_000330-T1 1579 EACAEATRPLMNSVESLTAYALSP 1602 ********************9887 PP == domain 10 score: 9.8 bits; conditional E-value: 0.0008 Talin_IBS2B 58 peakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaqaakplleavenlvafap 116 + a+ +++s+k a+++ + + +kal+ n ++ q+la ak++++a+++l+++++ FUN_000330-T1 1616 RSAQVPLIMSGKSMATSSTNYFNVAKALAVNSkDQPGWQQLALQAKAVSDAMRRLITAIK 1675 567888999999999999999999999999987888999999999999999999998765 PP == domain 11 score: 26.9 bits; conditional E-value: 4e-09 Talin_IBS2B 2 dqseldsaleaikqaceeLaepek..........................................nqqqvlsaAtdiakalsaLcnacrgasa 53 +q+e+d+ale+i+ ++L++++ + ++++ ++a+ +s L+ + ga++ FUN_000330-T1 1680 GQRECDEALEQINYTINQLDQASLaaisqvleprpenslqgfqaqmmqnliqmadvidplataaksEPENIGHRVAQMASFISPLTDHAVGAAS 1773 68999999999999999999999999999**********************************999999************************* PP Talin_IBS2B 54 ktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrlaqaakplleavenlvafa 115 ++ + + k +++ Ak+Va+++a+L k+ np e+ ++++aa+ + eav+ l + FUN_000330-T1 1774 QMADIQRKVDLLDQAKTVAECAAQLMYATKEGGGNPkFVEADPAISEAAQGMKEAVKDLSHTL 1836 ************************************889******************998766 PP == domain 12 score: 5.9 bits; conditional E-value: 0.013 Talin_IBS2B 6 ldsaleaikq.aceeLaepeknqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqrl 97 + +a++++ + a++ + +++++ + + +di++ +++++ r a ++ npe ++ + ++ ++Lv++ a+ +n+ +p ++++l FUN_000330-T1 1886 MTRAMKELTRrAQDMVGKSATDPTKLGPLGKDISRIYNDIAKDTRRAVKTVGNPEISLRIRTGVQGLGEACISLVQSGGAVQSNHkDPFSKKEL 1979 555555554304444444455666777788888889999999999999999999999999999999999999********99999999****** PP Talin_IBS2B 98 aqaakplleavenlvafap 116 a+ +++++e v+ l a+++ FUN_000330-T1 1980 ADNSRNVAEKVSHLLAALQ 1998 ***********99998875 PP == domain 13 score: 29.6 bits; conditional E-value: 5.8e-10 Talin_IBS2B 7 dsaleaikqaceeLaepeknqqqvlsaAtdia.kalsaLcnacr..gasaktsnpeakrkfvqsAkdVanktaaLvkeikallqnp.spenrqr 96 ++++++ + +++L ++++ q+vl++A ++a ++s+L+ ++ +++ +++++a++ ++++AkdVa++ aL++ k++ + s+ + ++ FUN_000330-T1 2050 LRTAKTLVEDTKNLVSAAQASQDVLASAAQSAvGSVSSLADNVKlgAIALGSDDSDAQQMLLNAAKDVASALGALINATKNASGKSvSDPAMEE 2143 45555555666666666666667766666555379*********666889999*******************************999******* PP Talin_IBS2B 97 laqaakplleavenlvafaps 117 l+++ k ++ v++l + ++s FUN_000330-T1 2144 LKTTGKTMVANVSSLLKTVKS 2164 **************9988776 PP == domain 14 score: 47.7 bits; conditional E-value: 1.4e-15 Talin_IBS2B 2 dqseldsaleaikqaceeLaepek...............................nqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkf 64 ++++l+s+++a+kqa e+++++ +q++++ aA++ +ka+++++ +c++a+ k +npea++++ FUN_000330-T1 2172 GTRALESTVDAVKQAVLEMQSSSMpvrdatpedlirstkdvtlatakavaagnscHQDDIITAANMGRKAVTEMLIICKAAAHKAENPEARSAA 2265 7899*******************9********************************************************************** PP Talin_IBS2B 65 vqsAkdVanktaaLvkeikallqnpspenrqrlaqaakplleavenlvafap 116 ++s+ ++ ++ ++++ + ++ q+p++e++q+l+ +k +++ v +lv +a+ FUN_000330-T1 2266 LRSGMECGASFGEMLDLVHNITQKPTQEKKQKLTPQSKMIADQVAKLVHAAE 2317 ************************************************9886 PP == domain 15 score: 12.4 bits; conditional E-value: 0.00012 Talin_IBS2B 5 eldsaleaikqaceeLaepek........................nqqqvlsaAtdiakalsaLcnacrgasaktsnpeakrkfvqsAkdVank 74 ++ +a++ai +a+ L ++++ q saA+++a a+++Lc a+ +a + ++ ++++ Ak V n+ FUN_000330-T1 2373 QILEAAKAITAATVALVKSASaaqkelvasgkvcspstdpnedgqWSQGLVSAARMVAAATTTLCDAANAAVQGNASE---ERLIAGAKQVSNS 2463 5566777777777777777779999999999999999999999997889******************97665554444...68*********** PP Talin_IBS2B 75 taaLvkeikallqnpspenrqrlaqaakplleavenlvafap 116 ta+L+ + + ++s ++rl++a +++ +a +nlv++a+ FUN_000330-T1 2464 TAQLLLACRVKADSNS-VTQRRLQTAGNAVKKAADNLVTAAK 2504 *****99987766665.889******************9986 PP >> TLN1-like_RS Talin 1-like, rod segment domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.4 0.0021 2.7 35 129 .. 552 652 .. 545 664 .. 0.81 2 ! 6.6 8.3 0.0084 11 75 159 .. 695 779 .. 685 785 .. 0.89 3 ! 23.8 8.4 4.5e-08 5.7e-05 41 151 .. 817 926 .. 799 937 .. 0.87 4 ! 17.3 0.9 4.5e-06 0.0057 77 136 .. 947 1006 .. 928 1031 .. 0.77 5 ! 30.0 5.2 5.3e-10 6.8e-07 1 156 [. 1069 1225 .. 1069 1231 .. 0.94 6 ! 21.9 7.4 1.7e-07 0.00022 28 157 .. 1243 1376 .. 1227 1381 .. 0.84 7 ! 7.2 0.0 0.0055 7 1 21 [. 1382 1402 .. 1382 1439 .. 0.85 8 ! 14.1 8.5 4.2e-05 0.054 43 154 .. 1487 1596 .. 1485 1599 .. 0.93 9 ? 2.9 0.2 0.12 1.5e+02 93 126 .. 1644 1677 .. 1612 1678 .. 0.64 10 ! 209.4 6.0 3.9e-65 4.9e-62 1 165 [] 1680 1844 .. 1680 1844 .. 0.99 11 ? 2.7 0.0 0.14 1.8e+02 38 159 .. 1878 1999 .. 1856 2002 .. 0.81 12 ! 35.1 7.4 1.5e-11 1.9e-08 1 162 [. 2003 2167 .. 2003 2170 .. 0.89 13 ? -1.9 0.1 3.5 4.5e+03 97 123 .. 2290 2316 .. 2276 2321 .. 0.72 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0021 TLN1-like_RS 35 ednslqafqeqllnsaqeildkiepvreAAkseaekL.....GhavtqlasyfepLvsaaigaASkllns.kqQmtlLdqtktvaesalqLvyaaK 124 ++n+l ++++++ +++++ + ++ + +e+e+ G+a+++++s ++ L ++ +A l + + ++lLd ++ +a + +L+ aa+ FUN_000330-T1 552 KQNTLDVSKQKVASRLAALSASCASIVTLTSGEPEETnytaaGAAINTISSNLQDLSKGIKMIAGLLDDDdDTSKSLLDAARNLAGAFSNLLKAAQ 647 567888888888888888888888888888888886333333999***********99988888887655156789******************** PP TLN1-like_RS 125 eaGGN 129 e+GG FUN_000330-T1 648 EGGGA 652 ****6 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0084 TLN1-like_RS 75 vtqlasyfepLvsaaigaASkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpkaaelheavdeaaeslkeaveellktlee 159 ++ +a++ Lv a +AS+ ++++Q+++++ +k a ++qLv ++K ++ ++e+v eaa+ + av++ +++ +e FUN_000330-T1 695 AQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATAVDDTESACKE 779 56778899999*****************************************999999999***************999887766 PP == domain 3 score: 23.8 bits; conditional E-value: 4.5e-08 TLN1-like_RS 41 afqeqllnsaqeildkiepvreAAkseaekLGhavtqlasyfepLvsaaigaASkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpkaaelh 136 + q +++++il + + ++ ++a ++ ++++ la++ Lv++ + A +s +Q+ lL +k +a+++++Lv aaK a+ Np+aa+ + FUN_000330-T1 817 QQAGQYDETCDDILGATDRLFNS-MGNAGEMVKQAKILAQASSSLVTGIKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKGAAKNPNAADQQ 911 55567778888888888888775.688999999999*******************************************************9999* PP TLN1-like_RS 137 eavdeaaeslkeave 151 +++ +aae l+ a + FUN_000330-T1 912 QKLKQAAEDLRSATN 926 **********99876 PP == domain 4 score: 17.3 bits; conditional E-value: 4.5e-06 TLN1-like_RS 77 qlasyfepLvsaaigaASkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpk.aaelh 136 + a ++L+ aa a n+ +Q++l dq+k v es + Lv + Ke G Np aa + FUN_000330-T1 947 EAAGQATQLIAAAQMAGPSNRNQTSQQQLDDQCKPVEESINHLVESLKETGRNPDvAAP-Q 1006 555666677777766666778899999***************************95544.3 PP == domain 5 score: 30.0 bits; conditional E-value: 5.3e-10 TLN1-like_RS 1 GqkeCddaieklnelireldqaslaavsqsLaprednslqafqeqllnsaqeildkiepvreAAkseaek.LGhavtqlasyfepLvsaaigaA 93 G e d+a++++ +l ++l + +a + +L p ++ + + +l + + + +++ + +AA + e+ G a+++ a++++ L+ aa g+A FUN_000330-T1 1069 GTLEIDSALDTVDSLNSDLKAYEKSAAEGKLIPLPGETAESCGLELGATSKTVGSSMAQLLTAASQGNESyTGIAARDTANALQVLTAAARGVA 1162 6679*****************************************************9999998766555279********************* PP TLN1-like_RS 94 SkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpkaaelheavdeaaeslkeaveellkt 156 + ++ Q +l+ t+ v+ +++L+ aK a Np ++++ +aa+++ +a++++++ FUN_000330-T1 1163 ATADDKALQLNLIKATQDVVAESAKLINEAKSAVNNPGDPGNQPRLAQAAKEVSQALNNCVNF 1225 ******************999999**************9999**************9999875 PP == domain 6 score: 21.9 bits; conditional E-value: 1.7e-07 TLN1-like_RS 28 sqsLa....prednslqafqeqllnsaqeildkiepvreAAkseaekLGhavtqlasyfepLvsaaigaASkllnskqQmtlLdqtktvaesal 117 sqsLa p +++ q +qe+l ++++ + + +A ++ +++L+++ ++++s ++ L ++ + A + ++ ++ +++ k ++ FUN_000330-T1 1243 SQSLAvedfPDTSEGYQVVQEKLSMRGAALNAAASEMVSASRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAKDEAAKDSMVRNLKNTSTASS 1336 233431111455667799999999999******************************************************************* PP TLN1-like_RS 118 qLvyaaKeaGGNpkaaelheavdeaaeslkeaveellktl 157 +L+ aaK +p+a ++++ + +aa+++ ++++ ll++ FUN_000330-T1 1337 KLLLAAKSLVSDPNAPNAKNSLANAARAVTDSINMLLNAC 1376 **********************************998875 PP == domain 7 score: 7.2 bits; conditional E-value: 0.0055 TLN1-like_RS 1 GqkeCddaieklnelireldq 21 GqkeCd+a+ +++ + + ld+ FUN_000330-T1 1382 GQKECDNALRNIQAVSNILDN 1402 9***************99997 PP == domain 8 score: 14.1 bits; conditional E-value: 4.2e-05 TLN1-like_RS 43 qeqllnsaqeildkiepvreAAkseaekLGhavtqlasyfepLvsaaigaASkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpkaaelh 136 q q lns qei d +++ + + + LG+a t +a+ L++a+ +a++k+ n ++ ++++ +k va+++++Lv +K +G+ +a+ + FUN_000330-T1 1487 QAQFLNSKQEIMDACQSLLNPEATQQQVLGAA-TAVAKHTSALCNACKAASAKTNNPAAKRQFVQAAKDVANNTANLVKNTKILAGDMSEAN-R 1578 57999***************999999999975.78999999***********************************************9776.8 PP TLN1-like_RS 137 eavdeaaeslkeaveell 154 ea ea++ l+++ve l+ FUN_000330-T1 1579 EACAEATRPLMNSVESLT 1596 9999**999999999875 PP == domain 9 score: 2.9 bits; conditional E-value: 0.12 TLN1-like_RS 93 ASkllnskqQmtlLdqtktvaesalqLvyaaKea 126 A ++ ++ ++l q+k+v +++ L++a+K++ FUN_000330-T1 1644 AVNSKDQPGWQQLALQAKAVSDAMRRLITAIKDN 1677 3333333333555568888888888888888886 PP == domain 10 score: 209.4 bits; conditional E-value: 3.9e-65 TLN1-like_RS 1 GqkeCddaieklnelireldqaslaavsqsLaprednslqafqeqllnsaqeildkiepvreAAkseaekLGhavtqlasyfepLvsaaigaAS 94 Gq+eCd+a+e++n i++ldqaslaa+sq L+pr +nslq+fq q+++++ +++d i+p+++AAkse+e++Gh+v q+as++ pL++ a+gaAS FUN_000330-T1 1680 GQRECDEALEQINYTINQLDQASLAAISQVLEPRPENSLQGFQAQMMQNLIQMADVIDPLATAAKSEPENIGHRVAQMASFISPLTDHAVGAAS 1773 9********************************************************************************************* PP TLN1-like_RS 95 kllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpkaaelheavdeaaeslkeaveellktleeaaseag 165 ++++ +++ +lLdq+ktvae+a+qL+ya+Ke+GGNpk e+ +a+ eaa+ +keav++l++tleeaase+g FUN_000330-T1 1774 QMADIQRKVDLLDQAKTVAECAAQLMYATKEGGGNPKFVEADPAISEAAQGMKEAVKDLSHTLEEAASESG 1844 *************************************999*****************************97 PP == domain 11 score: 2.7 bits; conditional E-value: 0.14 TLN1-like_RS 38 slqafqeqllnsaqeildkiepvreAAkseaekLGhavtqlasyfepLvsaaigaASkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpk 131 ++qe+++++++e++ +++ + ++ kLG ++++++++ +++ + a+ + n + + ++ + e+ + Lv++ N k FUN_000330-T1 1878 PFVNYQERMTRAMKELTRRAQDMVGKSATDPTKLGPLGKDISRIYNDIAKDTRRAVKTVGNPEISLRIRTGVQGLGEACISLVQSGGAVQSNHK 1971 5567899999999999998887777777789999999999999999999999888888888888888888888888999999888888888888 PP TLN1-like_RS 132 aaelheavdeaaeslkeaveellktlee 159 ++++ + +++ e v+ ll +l++ FUN_000330-T1 1972 DPFSKKELADNSRNVAEKVSHLLAALQQ 1999 8888888888888888888888887775 PP == domain 12 score: 35.1 bits; conditional E-value: 1.5e-11 TLN1-like_RS 1 GqkeCddaieklnelireldqaslaavsqsLapred.nslqafqeqllnsaqeildkiepvreAAkseaekLGha....vtqlasyfepLvsaa 89 G + C +a + ++ ++++ld l a +L+p+ + s +e +l++a+ + + + + +AA+ + L+ a v +++s+ +++ +a FUN_000330-T1 2003 GTQACINASSAVQGIVSDLDTTVLFAATGTLQPEVEgDSFGDRREAILRTAKTLVEDTKNLVSAAQASQDVLASAaqsaVGSVSSLADNVKLGA 2096 56679999999**********************866589999**************************99999872222555666666666778 PP TLN1-like_RS 90 igaASkllnskqQmtlLdqtktvaesalqLvyaaKeaGGNpkaaelheavdeaaeslkeaveellktleeaas 162 i+ S +s +Q++lL+ +k va + +L+ a+K+a G + + e++ + + + v+ llkt++++++ FUN_000330-T1 2097 IALGSD--DSDAQQMLLNAAKDVASALGALINATKNASGKSVSDPAMEELKTTGKTMVANVSSLLKTVKSVED 2167 888888..999*******************************999***********************98876 PP == domain 13 score: -1.9 bits; conditional E-value: 3.5 TLN1-like_RS 97 lnskqQmtlLdqtktvaesalqLvyaa 123 + ++++++l q+k +a+ ++Lv aa FUN_000330-T1 2290 PTQEKKQKLTPQSKMIADQVAKLVHAA 2316 445666777788888888888888777 PP >> I_LWEQ I/LWEQ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.3 2.6 3.3e+03 38 63 .. 552 577 .. 547 612 .. 0.68 2 ! 25.8 3.2 1e-08 1.3e-05 4 103 .. 621 720 .. 618 724 .. 0.87 3 ! 18.8 7.8 1.5e-06 0.0019 4 62 .. 684 745 .. 681 755 .. 0.88 4 ! 20.3 4.2 5e-07 0.00064 6 103 .. 720 821 .. 717 835 .. 0.88 5 ! 17.1 14.4 4.9e-06 0.0063 10 88 .. 845 928 .. 837 937 .. 0.85 6 ! 13.7 3.9 5.3e-05 0.068 39 97 .. 938 998 .. 927 1014 .. 0.85 7 ? 1.4 0.5 0.32 4.1e+02 41 97 .. 1008 1066 .. 999 1092 .. 0.77 8 ? 2.7 0.0 0.13 1.7e+02 41 63 .. 1113 1135 .. 1109 1140 .. 0.86 9 ! 15.3 6.9 1.7e-05 0.022 14 101 .. 1143 1235 .. 1142 1251 .. 0.78 10 ? -2.5 7.3 5.3 6.7e+03 21 112 .. 1235 1322 .. 1229 1346 .. 0.49 11 ! 6.8 3.7 0.0072 9.2 37 101 .. 1319 1385 .. 1310 1401 .. 0.67 12 ! 25.0 5.7 1.8e-08 2.3e-05 23 102 .. 1495 1576 .. 1481 1605 .. 0.54 13 ! 7.5 1.3 0.0045 5.7 65 130 .. 1647 1711 .. 1608 1727 .. 0.76 14 ! 7.7 1.5 0.0039 5 19 98 .. 1758 1842 .. 1752 1861 .. 0.82 15 ? 4.3 0.1 0.043 55 67 100 .. 1972 2005 .. 1949 2026 .. 0.68 16 ? 5.7 10.9 0.016 20 18 114 .. 2049 2151 .. 2043 2165 .. 0.66 17 ? 3.9 2.8 0.057 73 7 68 .. 2172 2225 .. 2166 2270 .. 0.74 18 ? 2.2 9.1 0.19 2.5e+02 5 98 .. 2292 2398 .. 2288 2409 .. 0.75 19 ! 162.7 12.1 7e-51 8.9e-48 3 151 .] 2414 2559 .. 2412 2559 .. 0.97 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.6 I_LWEQ 38 seeeLivaakevaastaqLvaasrvK 63 +++ L v++++va+ a L a++ FUN_000330-T1 552 KQNTLDVSKQKVASRLAALSASCASI 577 66778888888888888888877643 PP == domain 2 score: 25.8 bits; conditional E-value: 1e-08 I_LWEQ 4 nnrwtegLisaAkaVaeatnlLveaa.dkvvkgkaseeeLivaakevaastaqLvaasrvKadensktqerLeaaskavtsatkalvaavkeaaek 98 + ++ L+ aA++ a a + L +aa ++ + ++s +L++aa +v +s a L++ + +++tqe L a ++av +at+alv ++k++a++ FUN_000330-T1 621 DDDTSKSLLDAARNLAGAFSNLLKAAqEGGGADSESRGRLLSAAGNVGSSGASLLQF-MGEPEVDQRTQEMLLALAQAVANATAALVLKAKNIASE 715 5567899*******************66666777*******************9875.456667779999************************99 PP I_LWEQ 99 qeeee 103 +++ e FUN_000330-T1 716 ADDTE 720 99863 PP == domain 3 score: 18.8 bits; conditional E-value: 1.5e-06 I_LWEQ 4 nnrwtegLisaAkaVaeatnlLveaadkvvkgk...aseeeLivaakevaastaqLvaasrv 62 ++r +e L+ A+aVa at Lv +a++++++ ++++++i aake a taqLva +v FUN_000330-T1 684 DQRTQEMLLALAQAVANATAALVLKAKNIASEAddtENQNKVINAAKETARTTAQLVACVKV 745 6889999*******************99998877779999*****************98777 PP == domain 4 score: 20.3 bits; conditional E-value: 5e-07 I_LWEQ 6 rwtegLisaAkaVaeatnlLveaadkvvkgk...aseeeLivaakevaastaqLvaasrvKadensktqerLeaaskavtsatkalvaavkeaaek 98 + ++ i+aAk+ a +t Lv + + vv + +e+++ aak va+++ +a++ +s+ + ++ a++ v++a ++l+ +v+e+ + FUN_000330-T1 720 ENQNKVINAAKETARTTAQLVACVKVVVPSIsshMCQEQVVEAAKLVATAVDDTESACKEAVPGDSELLPEMMTAAQGVRDALNNLLIKVREGGRD 815 567889******************9998766333678*********************************************************99 PP I_LWEQ 99 qeee.e 103 ++++ + FUN_000330-T1 816 NQQAgQ 821 988741 PP == domain 5 score: 17.1 bits; conditional E-value: 4.9e-06 I_LWEQ 10 gLisaAkaVaeatnlLveaadkvvkgk...aseeeLivaakevaastaqLvaasr..vKadensktqerLeaaskavtsatkal 88 +++++Ak a+a ++Lv+ +++ ++ + +s+++L++aak +a +ta+Lv a++ +K+ + ++q++L++a+++++sat+a FUN_000330-T1 845 EMVKQAKILAQASSSLVTGIKAEAETQddsDSQKRLLAAAKVLADATAKLVEAAKgaAKNPNAADQQQKLKQAAEDLRSATNAA 928 799**************98866666555689********************99984477778888999************9875 PP == domain 6 score: 13.7 bits; conditional E-value: 5.3e-05 I_LWEQ 39 eeeLivaakevaastaqLvaasrvK..adensktqerLeaaskavtsatkalvaavkeaae 97 +L va+ke a + +qL+aa+++ +++n+ +q++L + k v +++++lv+++ke FUN_000330-T1 938 VRRLEVASKEAAGQATQLIAAAQMAgpSNRNQTSQQQLDDQCKPVEESINHLVESLKETGR 998 5689*******************9744678888999*******************998765 PP == domain 7 score: 1.4 bits; conditional E-value: 0.32 I_LWEQ 41 eLivaakevaastaqLvaasrvKadensktqe..rLeaaskavtsatkalvaavkeaae 97 Li ++ke t +Lva s++ + + +L + +k+ + ++l +a+++aae FUN_000330-T1 1008 ALINTSKEFIQPTSKLVANSKAALPTIGDPITatQLANFAKSTATSLAELREAAEKAAE 1066 68889999999999999999988887766544448888888888888888888887775 PP == domain 8 score: 2.7 bits; conditional E-value: 0.13 I_LWEQ 41 eLivaakevaastaqLvaasrvK 63 eL +++k v +s aqL++a+ FUN_000330-T1 1113 ELGATSKTVGSSMAQLLTAASQG 1135 67899************998765 PP == domain 9 score: 15.3 bits; conditional E-value: 1.7e-05 I_LWEQ 14 aAkaVaeatnlLveaadkvvkgk...aseeeLivaakevaastaqLvaasr..vKadensktqerLeaaskavtsatkalvaavkeaaekqee 101 aA++ a a ++L+ aa++v++ a + +Li+a ++v a+ a+L+ +++ v++ + +q rL +a+k+v++a ++ v+ + +++ +e FUN_000330-T1 1143 AARDTANALQVLTAAARGVAATAddkALQLNLIKATQDVVAESAKLINEAKsaVNNPGDPGNQPRLAQAAKEVSQALNNCVNFLPGQRDVDEA 1235 89****************9987765577789***************977661155555555677**************999877666655444 PP == domain 10 score: -2.5 bits; conditional E-value: 5.3 I_LWEQ 21 atnlLveaadkvvkgk..aseeeLivaakevaastaqLvaasrvKadensktqerLeaaskavtsatkalvaavkeaaekqeee..eeeeldfs 110 a++ v++ ++++ ++ +++e v ++++ a L aa+ ++ t+++L a+ k+++s+ + l+ + ++ a ++++e + FUN_000330-T1 1235 AIKAVVDSSQSLAVEDfpDTSEGYQVVQEKLSMRGAALNAAASEMVSASRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAKDEaaK------- 1321 444444444444444444555555555555555555555555555555555555666666666666666666555555554444211....... PP I_LWEQ 111 kl 112 FUN_000330-T1 1322 -D 1322 .1 PP == domain 11 score: 6.8 bits; conditional E-value: 0.0072 I_LWEQ 37 aseeeLivaakevaastaqLvaasr.vKadensktqe.rLeaaskavtsatkalvaavkeaaekqee 101 a ++ +++ k+ +++ +L+ a++ +d+n ++ + L +a++avt++++ l++a+++aa q+e FUN_000330-T1 1319 AAKDSMVRNLKNTSTASSKLLLAAKsLVSDPNAPNAKnSLANAARAVTDSINMLLNACMSAAPGQKE 1385 5556666666666666666666555145666666666689999999999999999888888765555 PP == domain 12 score: 25.0 bits; conditional E-value: 1.8e-08 I_LWEQ 23 nlLveaadkvvkgkaseeeLivaakevaastaqLvaasrvKad.ensktqe.rLeaaskavtsatkalvaavkeaaekqeee 102 + +++a++++++ +a++++++ aa +va++t L a+++ + +n+++ + + +a+k+v ++t++lv++ k a + +e+ FUN_000330-T1 1495 QEIMDACQSLLNPEATQQQVLGAATAVAKHTSALCNACKAASAkTNNPAAKrQFVQAAKDVANNTANLVKNTKILAGDMSEA 1576 5556666666666666666666666666666666666665433033333334666666666666666666666555444444 PP == domain 13 score: 7.5 bits; conditional E-value: 0.0045 I_LWEQ 65 densktqerLeaaskavtsatkalvaavkeaaekqeeeeeeeldfsklslhqakrqemeaqvkilk 130 +++++ ++L +kav++a+++l+ a+k+ a q+e +e l+ + + +q+ ++ + a +++l+ FUN_000330-T1 1647 SKDQPGWQQLALQAKAVSDAMRRLITAIKDNAPGQREC-DEALEQINYTINQLDQASLAAISQVLE 1711 33445667999999**************9999998887.688888888888888888777777775 PP == domain 14 score: 7.7 bits; conditional E-value: 0.0039 I_LWEQ 19 aeatnlLveaadkvvkgk...aseeeLivaakevaastaqLvaasrvKadensktqe..rLeaaskavtsatkalvaavkeaaek 98 a+ ++ L++ a +++++ + + L+ ak va + aqL+ a + ++ + ++++a++ +++a+k l ++++eaa++ FUN_000330-T1 1758 ASFISPLTDHAVGAASQMadiQRKVDLLDQAKTVAECAAQLMYATKEGGGNPKFVEAdpAISEAAQGMKEAVKDLSHTLEEAASE 1842 55556666666665555545567778999*****************99998887776689*****************99999876 PP == domain 15 score: 4.3 bits; conditional E-value: 0.043 I_LWEQ 67 nsktqerLeaaskavtsatkalvaavkeaaekqe 100 + ++++L + s++v +++++l+aa+++++ ++ FUN_000330-T1 1972 DPFSKKELADNSRNVAEKVSHLLAALQQGSRGTQ 2005 3345668889999999999999998888875444 PP == domain 16 score: 5.7 bits; conditional E-value: 0.016 I_LWEQ 18 VaeatnlLveaadkvvkgk.aseeeLivaake....vaastaqLvaasrvKadensktqerLeaaskavtsatkalvaavkeaaekqeee.eee 105 + ++++Lve +++v+ as++ L +aa++ v++ + + + +++s++q+ L +a+k+v sa al++a k+a+ k+ ++ + e FUN_000330-T1 2049 ILRTAKTLVEDTKNLVSAAqASQDVLASAAQSavgsVSSLADNVKLGAIALGSDDSDAQQMLLNAAKDVASALGALINATKNASGKSVSDpAME 2142 44455555555533333332567777777776111155555555555555568999*************************9998877765445 PP I_LWEQ 106 eldfsklsl 114 el+++ ++ FUN_000330-T1 2143 ELKTTGKTM 2151 555555544 PP == domain 17 score: 3.9 bits; conditional E-value: 0.057 I_LWEQ 7 wtegLisaAkaVaeatnlLveaadkvvkgkaseeeLivaakevaastaqLvaasrvKadens 68 t+ L s++ aV +a+ + ++ v a+ e Li++ k+v +ta+ vaa + s FUN_000330-T1 2172 GTRALESTVDAVKQAVLEMQSSSMPVRD--ATPEDLIRSTKDVTLATAKAVAAGN------S 2225 6788999999999999999888877655..99*****************999964......4 PP == domain 18 score: 2.2 bits; conditional E-value: 0.19 I_LWEQ 5 nrwtegLisaAkaVaeatnlLveaadkvvkgk.........aseeeLivaakevaastaqL...vaasrvKadensktqe.rLeaaskavtsat 85 ++ ++ L ++k++a+ + Lv+aa+++ + e+eL+ aa ++ a+ +L r K ++s + e ++ +a+ka+t+at FUN_000330-T1 2292 QEKKQKLTPQSKMIADQVAKLVHAAEALKGVNwvnpedpnvIAENELLGAAAAIEAAARKLaelKPKPRPKEADESLNFEeQILEAAKAITAAT 2385 55778899999999999999999998864444555546666678888888888888776651004566777777777766799*********** PP I_LWEQ 86 kalvaavkeaaek 98 alv+++ +a+++ FUN_000330-T1 2386 VALVKSASAAQKE 2398 ******9999875 PP == domain 19 score: 162.7 bits; conditional E-value: 7e-51 I_LWEQ 3 knnrwtegLisaAkaVaeatnlLveaadkvvkgkaseeeLivaakevaastaqLvaasrvKadensktqerLeaaskavtsatkalvaavkeaa 96 ++ +w++gL+saA++Va+at++L++aa+++v+g+asee+Li+ ak+v+ staqL+ a+rvKad+ns tq+rL+ a++av++a+++lv a+k+aa FUN_000330-T1 2414 EDGQWSQGLVSAARMVAAATTTLCDAANAAVQGNASEERLIAGAKQVSNSTAQLLLACRVKADSNSVTQRRLQTAGNAVKKAADNLVTAAKNAA 2507 789******************************************************************************************* PP I_LWEQ 97 ekqeeeeeeeldfsklslhqakrqemeaqvkilklekeLeearkkLaelRkakYk 151 +e+e ++ + +++ + ++qe+eaq+kil++ekeL +ar+kL+++R+akY+ FUN_000330-T1 2508 IFEEQE---TTVIINQRFVGGIAQELEAQEKILRIEKELAAARNKLSQIRQAKYR 2559 999886...467999***************************************6 PP >> Talin_R4 Talin, R4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.2 7.5 9.6e+03 42 88 .. 598 645 .. 553 649 .. 0.50 2 ! 31.8 8.7 1.5e-10 2e-07 31 126 .] 685 780 .. 678 780 .. 0.95 3 ! 21.9 4.8 1.8e-07 0.00023 34 124 .. 843 926 .. 831 928 .. 0.74 4 ! 133.3 9.6 5.9e-42 7.5e-39 1 126 [] 940 1064 .. 940 1064 .. 0.97 5 ! 30.7 7.2 3.3e-10 4.3e-07 3 117 .. 1115 1220 .. 1112 1222 .. 0.88 6 ! 10.3 8.2 0.00068 0.86 19 126 .] 1274 1379 .. 1266 1379 .. 0.90 7 ! 16.2 6.9 1e-05 0.013 22 98 .. 1500 1575 .. 1487 1597 .. 0.83 8 ! 10.8 0.5 0.0005 0.64 62 124 .. 1613 1675 .. 1607 1677 .. 0.87 9 ! 7.6 0.8 0.0046 5.9 17 125 .. 1730 1838 .. 1719 1839 .. 0.83 10 ? 4.9 0.0 0.034 43 81 124 .. 1955 1998 .. 1915 2023 .. 0.67 11 ! 8.3 6.5 0.0029 3.7 13 119 .. 2060 2158 .. 2048 2169 .. 0.73 12 ? 3.3 2.8 0.1 1.3e+02 29 88 .. 2290 2355 .. 2282 2397 .. 0.67 13 ! 13.7 8.3 6e-05 0.077 2 100 .. 2422 2513 .. 2421 2524 .. 0.86 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 7.5 Talin_R4 42 kevaeqiprlvqsikgsqaqp.ddpsaqlnLinaseeflqpatrlvea 88 ++++ ++ l ++ik ++ dd + +L++a+ ++ ++l++a FUN_000330-T1 598 NTISSNLQDLSKGIKMIAGLLdDDDDTSKSLLDAARNLAGAFSNLLKA 645 444444444444554444432122333344555555544444444444 PP == domain 2 score: 31.8 bits; conditional E-value: 1.5e-10 Talin_R4 31 assqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavptvtdqaaalqLsnsskqlataLaeLrsalnka 126 + +qe L + ++va+ ++ lv k+++++ dd++ q + ina++e +++++lv+ k +vp+++ +++ q+ +++k +ata+ + sa+++a FUN_000330-T1 685 QRTQEMLLALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATAVDDTESACKEA 780 567999999***********************************************************************************9886 PP == domain 3 score: 21.9 bits; conditional E-value: 1.8e-07 Talin_R4 34 qeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavptvtdqaaalqLsnsskqlataLaeLrsaln 124 e++++ k +a+ +lv++ik+ ++++dd+ +q +L+ a++ + +++lveaak a+ + + aa q ++l++a ++Lrsa n FUN_000330-T1 843 AGEMVKQAKILAQASSSLVTGIKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKGAAKN---PNAADQ----QQKLKQAAEDLRSATN 926 55788899999999999999999999999999999999999999999999999999988754...444433....3445555555555555 PP == domain 4 score: 133.3 bits; conditional E-value: 5.9e-42 Talin_R4 1 rLeqaAkqaaaaatQlIaAaqaaaslnknnassqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavp 94 rLe a+k+aa +atQlIaAaq a ++n+n+ +sq++L +ck v+e+i++lv+s+k++ ++pd ++ ql+Lin s+ef+qp+++lv+++kaa+p FUN_000330-T1 940 RLEVASKEAAGQATQLIAAAQMAGPSNRNQ-TSQQQLDDQCKPVEESINHLVESLKETGRNPDVAAPQLALINTSKEFIQPTSKLVANSKAALP 1032 79**********************998766.56889********************************************************** PP Talin_R4 95 tvtdqaaalqLsnsskqlataLaeLrsalnka 126 t+ d+ +a+qL+n++k++at+LaeLr a++ka FUN_000330-T1 1033 TIGDPITATQLANFAKSTATSLAELREAAEKA 1064 ******************************98 PP == domain 5 score: 30.7 bits; conditional E-value: 3.3e-10 Talin_R4 3 eqaAkqaaaaatQlIaAaqaaaslnknnassqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavptv 96 ++k ++ Ql++Aa++++++++ + + +a+ + l ++ +g++a+ dd++ qlnLi+a++++++ +++l++ ak+av++ FUN_000330-T1 1115 GATSKTVGSSMAQLLTAASQGNESYTG-------I--AARDTANALQVLTAAARGVAATADDKALQLNLIKATQDVVAESAKLINEAKSAVNNP 1199 567888888999999999866665422.......2..3478999999*********************************************** PP Talin_R4 97 tdqaaalqLsnsskqlataLa 117 d+ L++++k++++aL+ FUN_000330-T1 1200 GDPGNQPRLAQAAKEVSQALN 1220 *******************98 PP == domain 6 score: 10.3 bits; conditional E-value: 0.00068 Talin_R4 19 AaqaaaslnknnassqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavptvtdqaaalqLsnsskql 112 A aa+++ ++ + ++La+++k+ + + l+ s + + q +d++a+ +++++ ++ +++l+ aak+ v + + a ++L+n+++++ FUN_000330-T1 1274 A--AASEMVSASRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAKDEAAKDSMVRNLKNTSTASSKLLLAAKSLVSDPNAPNAKNSLANAARAV 1365 2..234455566778899**************************************************************************** PP Talin_R4 113 ataLaeLrsalnka 126 + +++ L +a+ +a FUN_000330-T1 1366 TDSINMLLNACMSA 1379 *****999998765 PP == domain 7 score: 16.2 bits; conditional E-value: 1e-05 Talin_R4 22 aaaslnknnassqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavptvtd 98 a++sl + +a++q ++ ++va+++ l ++ k+++a+ ++p+a+ + ++a++++ + +++lv+++k + +++ FUN_000330-T1 1500 ACQSLLNPEATQQ-QVLGAATAVAKHTSALCNACKAASAKTNNPAAKRQFVQAAKDVANNTANLVKNTKILAGDMSE 1575 4777776666655.566889************************************************988777666 PP == domain 8 score: 10.8 bits; conditional E-value: 0.0005 Talin_R4 62 pddpsaqlnLinaseeflqpatrlveaakaavptvtdqaaalqLsnsskqlataLaeLrsaln 124 ++ +saq+ Li + +++ +t+ +++aka + + +dq qL+ +k+++ a+ L +a++ FUN_000330-T1 1613 EEARSAQVPLIMSGKSMATSSTNYFNVAKALAVNSKDQPGWQQLALQAKAVSDAMRRLITAIK 1675 567899999999999999999999999999999999999999999999999999999988876 PP == domain 9 score: 7.6 bits; conditional E-value: 0.0046 Talin_R4 17 IaAaqaaaslnknnassqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaa..vptvtdqaaalqLsns 108 I a ++l + +s+ e++ + ++a i +l g+++q d + +++L+++++ + + a++l+ a+k p++ ++ +s++ FUN_000330-T1 1730 IQMADVIDPLATAAKSEPENIGHRVAQMASFISPLTDHAVGAASQMADIQRKVDLLDQAKTVAECAAQLMYATKEGggNPKFVEADP--AISEA 1821 56666667777788888899999999************************************************9622566666555..56899 PP Talin_R4 109 skqlataLaeLrsalnk 125 ++ +++a+++L l++ FUN_000330-T1 1822 AQGMKEAVKDLSHTLEE 1838 99999999999877766 PP == domain 10 score: 4.9 bits; conditional E-value: 0.034 Talin_R4 81 patrlveaakaavptvtdqaaalqLsnsskqlataLaeLrsaln 124 + +lv++ a++ + +d+ + +L+ +s+++a++++ L +al+ FUN_000330-T1 1955 ACISLVQSGGAVQSNHKDPFSKKELADNSRNVAEKVSHLLAALQ 1998 45555555555555555555555555555555555555555544 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0029 Talin_R4 13 atQlIaAaqaaaslnknnassqeeLaqeckevaeqiprlvqsik..gsqaqpddpsaqlnLinaseeflqpatrlveaakaavp.tvtdqaaal 103 + l++ + sq+ La+ ++ +++ +l +k +++ dd+ aq+ L+na++++ + l++a+k+a +v+d+a+ FUN_000330-T1 2060 TKNLVS----------AAQASQDVLASAAQSAVGSVSSLADNVKlgAIALGSDDSDAQQMLLNAAKDVASALGALINATKNASGkSVSDPAM-E 2142 444444..........445556666677777777777777777732344557999*************************998626777765.7 PP Talin_R4 104 qLsnsskqlataLaeL 119 +L+++ k++ ++++ L FUN_000330-T1 2143 ELKTTGKTMVANVSSL 2158 8999999999998877 PP == domain 12 score: 3.3 bits; conditional E-value: 0.1 Talin_R4 29 nnassqeeLaqeckevaeqiprlvqs...ikgsq.aqpddp..saqlnLinaseeflqpatrlvea 88 +++++++L+ + k +a+q+++lv++ +kg++ +p+dp a +L+ a+ ++ + a +l+e FUN_000330-T1 2290 PTQEKKQKLTPQSKMIADQVAKLVHAaeaLKGVNwVNPEDPnvIAENELLGAAAAIEAAARKLAEL 2355 34567889****************861114444323566663346667777777776666666665 PP == domain 13 score: 13.7 bits; conditional E-value: 6e-05 Talin_R4 2 LeqaAkqaaaaatQlIaAaqaaaslnknnassqeeLaqeckevaeqiprlvqsikgsqaqpddpsaqlnLinaseeflqpatrlveaakaavpt 95 L +aA+ aaa+t l Aa+aa + n a s+e+L++ k+v++++++l+ + + + +++ +q +L +a +++ + a +lv+aak+a+ FUN_000330-T1 2422 LVSAARMVAAATTTLCDAANAAVQGN---A-SEERLIAGAKQVSNSTAQLLLACRVKA--DSNSVTQRRLQTAGNAVKKAADNLVTAAKNAA-I 2508 779****************9998764...3.5789*******************9765..788999***********************985.4 PP Talin_R4 96 vtdqa 100 +++q FUN_000330-T1 2509 FEEQE 2513 55555 PP >> Talin_middle Talin, middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 193.9 4.1 2e-60 2.5e-57 1 161 [] 511 675 .. 511 675 .. 0.97 2 ? -0.2 5.0 1 1.3e+03 100 135 .. 708 743 .. 682 773 .. 0.56 3 ! 9.4 7.6 0.0011 1.4 96 157 .. 859 925 .. 849 929 .. 0.80 4 ? 2.8 7.2 0.12 1.5e+02 60 156 .. 1121 1218 .. 1114 1223 .. 0.77 5 ! 8.0 7.7 0.003 3.8 47 156 .. 1259 1368 .. 1240 1373 .. 0.88 6 ? 3.3 7.8 0.084 1.1e+02 20 133 .. 1488 1597 .. 1471 1619 .. 0.82 7 ? -1.4 1.7 2.4 3e+03 54 137 .. 1722 1804 .. 1666 1823 .. 0.69 8 ? 1.4 0.1 0.33 4.2e+02 115 153 .. 1977 2014 .. 1964 2030 .. 0.63 9 ! 6.3 8.0 0.0097 12 63 139 .. 2059 2132 .. 2040 2138 .. 0.72 10 ? -1.5 0.1 2.5 3.2e+03 80 80 .. 2173 2173 .. 2138 2246 .. 0.48 11 ? 0.9 3.5 0.44 5.6e+02 15 137 .. 2344 2394 .. 2287 2412 .. 0.65 12 ! 6.4 1.3 0.0092 12 109 161 .] 2414 2468 .. 2410 2468 .. 0.89 13 ? -1.7 0.2 2.9 3.7e+03 80 102 .. 2485 2507 .. 2473 2550 .. 0.76 Alignments for each domain: == domain 1 score: 193.9 bits; conditional E-value: 2e-60 Talin_middle 1 aqrallstisagqeavekaekeleekaqlpplgsdaaslkwkenkldvskqnvssqvaAinaatAsvvtltsgdeeevdytavgaaittissnlpe 96 aq+a++s++s+g +++++aekel +++q+p+lgsd+aslkwk+n+ldvskq+v+s++aA++a++As+vtltsg++ee++yta gaai+tissnl++ FUN_000330-T1 511 AQKAYMSSLSQGLNTIDSAEKELGSPTQVPALGSDPASLKWKQNTLDVSKQKVASRLAALSASCASIVTLTSGEPEETNYTAAGAAINTISSNLQD 606 79********************************************************************************************** PP Talin_middle 97 mskdvkliaaLmdde.kegdkLleAareLagafsdllkaaepes...kekrqnllnaAnrvGeasaalL 161 +sk++k+ia+L dd+ +++++Ll+Aar+Lagafs+llkaa++ +e+r ll+aA++vG+++a+lL FUN_000330-T1 607 LSKGIKMIAGLLDDDdDTSKSLLDAARNLAGAFSNLLKAAQEGGgadSESRGRLLSAAGNVGSSGASLL 675 **********99888577899********************9877779****************99987 PP == domain 2 score: -0.2 bits; conditional E-value: 1 Talin_middle 100 dvkliaaLmddekegdkLleAareLagafsdllkaa 135 ++k ia+ dd ++++k+++Aa+e a ++l+ + FUN_000330-T1 708 KAKNIASEADDTENQNKVINAAKETARTTAQLVACV 743 345566666666677777777777776666665544 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0011 Talin_middle 96 emskdvkliaaLmddekegdkLleAareLagafsdllkaae.....peskekrqnllnaAnrvGeas 157 ++ +++k a +dd++++++Ll Aa+ La a ++l++aa+ p+++ ++q+l +aA + +a+ FUN_000330-T1 859 SLVTGIKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKgaaknPNAADQQQKLKQAAEDLRSAT 925 5567889999999*************************98622222666888999999998877766 PP == domain 4 score: 2.8 bits; conditional E-value: 0.12 Talin_middle 60 inaatAsvvtltsgdeeevdytavgaaittissnlpemskdvkliaaLmddekegdkLleAareLagafsdllkaaepes.....kekrqnlln 148 + ++ A+++t +s+ +e+ yt++ a + l+ ++ ++ +aa dd+ + +L++A+++ ++ ++l++ a+ ++ l + FUN_000330-T1 1121 VGSSMAQLLTAASQGNES--YTGI--AARDTANALQVLTAAARGVAATADDKALQLNLIKATQDVVAESAKLINEAKSAVnnpgdPGNQPRLAQ 1210 567889998887777777..7776..45677899***************************************988654411211444556777 PP Talin_middle 149 aAnrvGea 156 aA +v +a FUN_000330-T1 1211 AAKEVSQA 1218 77777665 PP == domain 5 score: 8.0 bits; conditional E-value: 0.003 Talin_middle 47 dvskqnvssqvaAinaatAsvvtltsgdeeevdytavgaaittissnlpemskdvkliaaLmddekegdkLleAareLagafsdllkaae.... 136 +v ++++s + aA+naa++++v+ ++g ++ + a+ + ss+ +++ + +a+ de +d++++ ++ ++a s+ll aa+ FUN_000330-T1 1259 QVVQEKLSMRGAALNAAASEMVSASRGTSNQ-----LAASTKKFSSSYQDLLDSGMKLAGQAKDEAAKDSMVRNLKNTSTASSKLLLAAKslvs 1347 56778888999************99998888.....99***************9999*****************************99854444 PP Talin_middle 137 .peskekrqnllnaAnrvGea 156 p++ + +++l naA v ++ FUN_000330-T1 1348 dPNAPNAKNSLANAARAVTDS 1368 488899999999999988766 PP == domain 6 score: 3.3 bits; conditional E-value: 0.084 Talin_middle 20 ekeleekaqlpplgsdaaslkwkenkldvskqnvssqvaAinaatAsvvtltsgdeeevdytavgaaittissnlpemskdvkliaaLmddeke 113 ++ l++k+++ + ++ + ++++ + +v+ + +A+ a+ + t+++ ++ + v aa + ++ n ++ k+ k +a+ m + + FUN_000330-T1 1488 AQFLNSKQEIMDACQSLLNPEATQQQVLGAATAVAKHTSALCNACKAASAKTNNPAAK--RQFVQAA-KDVANNTANLVKNTKILAGDMSEA-N 1577 5567888888888888888889999999999999999999999999988889888888..5666665.889****************99888.9 PP Talin_middle 114 gdkLleAareLagafsdllk 133 +++ eA+r L++ +++l FUN_000330-T1 1578 REACAEATRPLMNSVESLTA 1597 **************999864 PP == domain 7 score: -1.4 bits; conditional E-value: 2.4 Talin_middle 54 ssqvaAinaatAsvvtltsgdeeevdytavgaaittissnlpemskdvkliaaLmddekegdkLleAareLagafsdllkaaep 137 ++q+ A v+ + ++ + + +g +++++s + ++ ++ a+ m d +++ +Ll+ a++ a+ ++l+ a ++ FUN_000330-T1 1722 QAQMMQNLIQMADVIDPLATAAKS-EPENIGHRVAQMASFISPLTDHAVGAASQMADIQRKVDLLDQAKTVAECAAQLMYATKE 1804 555555555556666544444444.56778999999999999999888888888888889999999999999999999988776 PP == domain 8 score: 1.4 bits; conditional E-value: 0.33 Talin_middle 115 dkLleAareLagafsdllkaaepeskekrqnllnaAnrv 153 ++L + +r+ a+ +s+ll a + s+ q +na + v FUN_000330-T1 1977 KELADNSRNVAEKVSHLLAALQQGSR-GTQACINASSAV 2014 55666666666666666666655443.345555555544 PP == domain 9 score: 6.3 bits; conditional E-value: 0.0097 Talin_middle 63 atAsvvtltsgdeeevdytavgaaittissnlpemskdvklia.aL.mddekegdkLleAareLagafsdllkaaepes 139 t ++v+ ++ ++v ++a +a+ +ss ++ +vkl a aL dd++ ++ Ll+Aa++ a+a+ +l++a + s FUN_000330-T1 2059 DTKNLVSA-AQASQDVLASAAQSAVGSVSS----LADNVKLGAiALgSDDSDAQQMLLNAAKDVASALGALINATKNAS 2132 55556653.455677788888888888887....66677764435514555788899*****************98776 PP == domain 10 score: -1.5 bits; conditional E-value: 2.5 Talin_middle 80 y 80 + FUN_000330-T1 2173 T 2173 2 PP == domain 11 score: 0.9 bits; conditional E-value: 0.44 Talin_middle 15 avekaekeleekaqlpplgsdaaslkwkenkldvskqnvssqvaAinaatAsvvtltsgdeeevdytavgaaittissnlpemskdvkliaaLm 108 a+e+a+++l+e + p+ + + sl++ e+ FUN_000330-T1 2344 AIEAAARKLAELKPKPRPKEADESLNFEEQI--------------------------------------------------------------- 2374 4555555555555555555555555555555............................................................... PP Talin_middle 109 ddekegdkLleAareLagafsdllkaaep 137 leAa+ +++a +l+k+a FUN_000330-T1 2375 ---------LEAAKAITAATVALVKSASA 2394 .........55555555555555555533 PP == domain 12 score: 6.4 bits; conditional E-value: 0.0092 Talin_middle 109 ddekegdkLleAareLagafsdllkaaepes..kekrqnllnaAnrvGeasaalL 161 +d + ++ L++Aar a+a l +aa+ +++ + l+ A +v +++a+lL FUN_000330-T1 2414 EDGQWSQGLVSAARMVAAATTTLCDAANAAVqgNASEERLIAGAKQVSNSTAQLL 2468 56668899******************9987666889999************9997 PP == domain 13 score: -1.7 bits; conditional E-value: 2.9 Talin_middle 80 ytavgaaittissnlpemskdvk 102 +++ g a++ + nl ++k+++ FUN_000330-T1 2485 LQTAGNAVKKAADNLVTAAKNAA 2507 56677788888888887777754 PP >> Talin_VBS2 Talin VBS2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.4 0.055 70 54 90 .. 619 656 .. 596 676 .. 0.69 2 ! 10.6 6.4 0.00062 0.79 51 103 .. 679 731 .. 660 741 .. 0.80 3 ! 11.9 9.3 0.00025 0.32 31 107 .. 693 769 .. 684 781 .. 0.87 4 ? 4.2 1.3 0.063 81 30 108 .. 726 802 .. 722 805 .. 0.62 5 ! 135.7 12.0 1e-42 1.3e-39 2 115 .. 819 932 .. 818 933 .. 0.98 6 ? -1.0 0.5 2.5 3.2e+03 61 100 .. 939 978 .. 936 991 .. 0.83 7 ? 0.6 0.5 0.81 1e+03 34 85 .. 1014 1065 .. 1006 1072 .. 0.88 8 ! 7.5 4.9 0.006 7.7 32 110 .. 1143 1221 .. 1119 1225 .. 0.84 9 ? -1.2 0.8 2.9 3.7e+03 36 88 .. 1272 1322 .. 1263 1343 .. 0.70 10 ? 1.9 2.5 0.32 4e+02 28 97 .. 1323 1390 .. 1318 1400 .. 0.72 11 ? -2.4 0.0 7 8.9e+03 29 81 .. 1419 1473 .. 1415 1498 .. 0.57 12 ! 8.6 5.5 0.0027 3.5 28 92 .. 1513 1576 .. 1490 1596 .. 0.78 13 ? 1.9 0.5 0.32 4.1e+02 36 94 .. 1629 1688 .. 1619 1709 .. 0.74 14 ! 11.4 0.9 0.00036 0.46 41 108 .. 1762 1829 .. 1742 1835 .. 0.85 15 ? -1.5 5.6 3.5 4.5e+03 30 107 .. 2050 2120 .. 2028 2131 .. 0.47 16 ? -0.5 6.4 1.7 2.2e+03 15 97 .. 2059 2144 .. 2051 2157 .. 0.67 17 ? -1.3 1.2 3.1 4e+03 51 93 .. 2219 2261 .. 2179 2273 .. 0.67 18 ? 4.9 0.6 0.038 48 58 83 .. 2293 2318 .. 2281 2353 .. 0.75 19 ? -1.8 3.4 4.5 5.7e+03 52 84 .. 2363 2395 .. 2341 2402 .. 0.87 20 ? 5.1 11.3 0.032 41 29 115 .. 2422 2506 .. 2414 2508 .. 0.80 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.055 Talin_VBS2 54 eidlenskkllaaaklladatakmveaak.gaaanpes 90 + d + sk ll aa+ la a +++++aa+ g a+ es FUN_000330-T1 619 DDDDDTSKSLLDAARNLAGAFSNLLKAAQeGGGADSES 656 45667899999999999999999999886244554443 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00062 Talin_VBS2 51 aeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrlreaaeg 103 e e+d lla a+ +a+ata +v ak a++ ++ e+q+++ +aa+ FUN_000330-T1 679 GEPEVDQRTQEMLLALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKE 731 57889999999999999999999999999999999999888888877777643 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00025 Talin_VBS2 31 rqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrlreaaeglrva 107 a+ +a+at+ lv k a d en +k++ aak a +ta++v + k s q+++ eaa+ + a FUN_000330-T1 693 ALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATA 769 4588899*******99999999999*******************************999*999999***99876665 PP == domain 4 score: 4.2 bits; conditional E-value: 0.063 Talin_VBS2 30 vrqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrlreaaeglrvat 108 + a+ a++t++lv ++k + + +++ aakl+a a a+k a p + e + aa+g+r a FUN_000330-T1 726 INAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATAVDDTESACKEA--VPGDSELLPEMMTAAQGVRDAL 802 4455666777777777777777776666667777777777777766665555543..3555555566666667766665 PP == domain 5 score: 135.7 bits; conditional E-value: 1e-42 Talin_VBS2 2 igrydqatdtiltvtesifssmgdagemvrqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrl 97 +g+yd++ d il t+ +f smg+agemv+qa++laqa+s lv ika+ae++ d + k+llaaak+ladatak+veaakgaa np++ +qqq+l FUN_000330-T1 819 AGQYDETCDDILGATDRLFNSMGNAGEMVKQAKILAQASSSLVTGIKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKGAAKNPNAADQQQKL 914 79********************************************************************************************** PP Talin_VBS2 98 reaaeglrvatnaaaqna 115 ++aae lr atnaaa +a FUN_000330-T1 915 KQAAEDLRSATNAAASDA 932 ***************988 PP == domain 6 score: -1.0 bits; conditional E-value: 2.5 Talin_VBS2 61 kkllaaaklladatakmveaakgaaanpeseeqqqrlrea 100 ++l a+k a +++++ aa+ a ++ qq+l + FUN_000330-T1 939 RRLEVASKEAAGQATQLIAAAQMAGPSNRNQTSQQQLDDQ 978 677789999999999******9999888888889988765 PP == domain 7 score: 0.6 bits; conditional E-value: 0.81 Talin_VBS2 34 rvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaa 85 + + q ts lv ka + d + +l ak a + a + eaa aa FUN_000330-T1 1014 KEFIQPTSKLVANSKAALPTIGDPITATQLANFAKSTATSLAELREAAEKAA 1065 556799999**9999999999999999*********************9987 PP == domain 8 score: 7.5 bits; conditional E-value: 0.006 Talin_VBS2 32 qarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrlreaaeglrvatna 110 ar a+a l a + a + d +l+ a++ + +ak+++ ak a np + +q rl +aa+ + a n FUN_000330-T1 1143 AARDTANALQVLTAAARGVAATADDKALQLNLIKATQDVVAESAKLINEAKSAVNNPGDPGNQPRLAQAAKEVSQALNN 1221 4666777777888888888888888888888999998888888***************************999888775 PP == domain 9 score: -1.2 bits; conditional E-value: 2.9 Talin_VBS2 36 laqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanp 88 l a+s++v a + ++ +kk+ ++ + l d+ k+ ak aa+ FUN_000330-T1 1272 LNAAASEMVSASRGTSNQ--LAASTKKFSSSYQDLLDSGMKLAGQAKDEAAKD 1322 566778888887765443..234556777777889999999999999888875 PP == domain 10 score: 1.9 bits; conditional E-value: 0.32 Talin_VBS2 28 emvrqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrl 97 mvr+ + + a+s l+ a k+ + + l aa+ ++d+ +++a+ aa ++e ++ l FUN_000330-T1 1323 SMVRNLKNTSTASSKLLLAAKSLVSDPNAPNAKNSLANAARAVTDSINMLLNACMSAAP--GQKECDNAL 1390 69999999999999999999997765544444445667899999999999999887764..444444444 PP == domain 11 score: -2.4 bits; conditional E-value: 7 Talin_VBS2 29 mvrqarvlaqatsdlvnaikadaeaeidlenskkllaaakllada...takmveaa 81 + rq+ l++a + n+ik+ e d+ + a l+++ +a +v a FUN_000330-T1 1419 VTRQSHDLTEALPRISNSIKSGDFNEFDVGV-RDASGAVCALTESaaqAAYLVAVA 1473 5688888888999999999998888888743.333333333333300034445444 PP == domain 12 score: 8.6 bits; conditional E-value: 0.0027 Talin_VBS2 28 emvrqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpesee 92 +++ a +a+ ts l na ka + + ++++ aak +a+ ta++v+ +k a + se FUN_000330-T1 1513 QVLGAATAVAKHTSALCNACKAASAKTNNPAAKRQFVQAAKDVANNTANLVKNTKILAGDM-SEA 1576 556678889*************998888999999******************999877654.333 PP == domain 13 score: 1.9 bits; conditional E-value: 0.32 Talin_VBS2 36 laqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaa.npeseeqq 94 +a ++++ n ka a d ++l ak ++da +++ a k a + e +e FUN_000330-T1 1629 MATSSTNYFNVAKALAVNSKDQPGWQQLALQAKAVSDAMRRLITAIKDNAPgQRECDEAL 1688 667777888999999999999999999999999999999999999997664144444444 PP == domain 14 score: 11.4 bits; conditional E-value: 0.00036 Talin_VBS2 41 sdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrlreaaeglrvat 108 s l + a +d++ ll ak +a+++a+++ a+k np+ e + + eaa+g++ a FUN_000330-T1 1762 SPLTDHAVGAASQMADIQRKVDLLDQAKTVAECAAQLMYATKEGGGNPKFVEADPAISEAAQGMKEAV 1829 5555555566777889999999*****************************************99876 PP == domain 15 score: -1.5 bits; conditional E-value: 3.5 Talin_VBS2 30 vrqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaak.gaaa.npeseeqqqrlreaaeglrva 107 +r a+ l + t +lv a +a d+ l +aa+ + + + + k ga a ++ + qq l +aa+ + a FUN_000330-T1 2050 LRTAKTLVEDTKNLVSAAQAS----QDV-----LASAAQSAVGSVSSLADNVKlGAIAlGSDDSDAQQMLLNAAKDVASA 2120 466666666666666554332....222.....22233333333333333333233221234445555555555544433 PP == domain 16 score: -0.5 bits; conditional E-value: 1.7 Talin_VBS2 15 vtesifssmgdagemvrqa.rvlaqatsdlvnaik..adaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrl 97 t+++ s+ + +++ a + + s l + +k a a + d + + ll aak +a a +++a+k a+ + s+ + l FUN_000330-T1 2059 DTKNLVSAAQASQDVLASAaQSAVGSVSSLADNVKlgAIALGSDDSDAQQMLLNAAKDVASALGALINATKNASGKSVSDPAMEEL 2144 55566555555555444430333445677777777224455677888999999*****************9998877666555555 PP == domain 17 score: -1.3 bits; conditional E-value: 3.1 Talin_VBS2 51 aeaeidlenskkllaaaklladatakmveaakgaaanpeseeq 93 a a + +++aa++ a + m+ +k aa + e+ e FUN_000330-T1 2219 AVAAGNSCHQDDIITAANMGRKAVTEMLIICKAAAHKAENPEA 2261 3333333445578899999999999999999999888887554 PP == domain 18 score: 4.9 bits; conditional E-value: 0.038 Talin_VBS2 58 enskkllaaaklladatakmveaakg 83 e+ +kl +k++ad ak+v aa FUN_000330-T1 2293 EKKQKLTPQSKMIADQVAKLVHAAEA 2318 77899****************98854 PP == domain 19 score: -1.8 bits; conditional E-value: 4.5 Talin_VBS2 52 eaeidlenskkllaaaklladatakmveaakga 84 ea+ l+ ++l aak ++ at +v++a a FUN_000330-T1 2363 EADESLNFEEQILEAAKAITAATVALVKSASAA 2395 77778888999****************999766 PP == domain 20 score: 5.1 bits; conditional E-value: 0.032 Talin_VBS2 29 mvrqarvlaqatsdlvnaikadaeaeidlenskkllaaaklladatakmveaakgaaanpeseeqqqrlreaaeglrvatn...aaaqna 115 +v ar++a at+ l +a +a ++++ +l+a ak ++++ta+++ a++ a + q+rl+ a + ++ a++ +aa+na FUN_000330-T1 2422 LVSAARMVAAATTTLCDAANAAVQGNASE---ERLIAGAKQVSNSTAQLLLACRVKAD--SNSVTQRRLQTAGNAVKKAADnlvTAAKNA 2506 7899**************99999998754...58****************99987654..345578899999999887764233455554 PP >> IRS PTB domain (IRS-1 type) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 111.2 0.0 2e-35 2.6e-32 1 92 [] 324 411 .. 324 411 .. 0.98 Alignments for each domain: == domain 1 score: 111.2 bits; conditional E-value: 2e-35 IRS 1 fvvkekakgknklvpeyllaitkesvvlvdektkevlvtwpltsirrwgasktsFsleaGrrcdtgegeltfqTsegeeiaqliasyikail 92 f+vkek+kgknklvp+ ll++tkes+++vdektkev++twplt++rrw+as++sF+l++G+ + e+++++qT ege+i+qlia+yi++il FUN_000330-T1 324 FLVKEKMKGKNKLVPR-LLGVTKESILRVDEKTKEVMKTWPLTTVRRWAASPNSFTLDFGD-YL--ESYYSVQTIEGEKISQLIAGYIDIIL 411 89**************.********************************************.88..9**********************996 PP >> VBS Vinculin Binding Site # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.82 1e+03 70 123 .. 602 649 .. 563 651 .. 0.77 2 ? -1.2 3.4 2.5 3.2e+03 32 117 .. 689 774 .. 682 780 .. 0.85 3 ! 6.8 0.8 0.0086 11 12 114 .. 1117 1220 .. 1113 1228 .. 0.88 4 ! 16.5 1.1 8.3e-06 0.011 13 120 .. 1269 1376 .. 1257 1380 .. 0.92 5 ! 6.7 0.1 0.0091 12 33 121 .. 1717 1803 .. 1706 1807 .. 0.79 6 ! 101.2 0.0 5.3e-32 6.8e-29 2 125 .] 1879 2002 .. 1878 2002 .. 0.99 7 ? 0.4 0.4 0.8 1e+03 2 63 .. 2042 2103 .. 2041 2157 .. 0.82 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.82 VBS 70 trvqelghgcialvtkagalqvspsdvytkkeliecaravsekvslvlaalqag 123 +q+l +g ++ ag l+ d t k l++ ar+++ s +l a q g FUN_000330-T1 602 SNLQDLSKGIKMI---AGLLD---DDDDTSKSLLDAARNLAGAFSNLLKAAQEG 649 4556666655443...55553...688899******************999987 PP == domain 2 score: -1.2 bits; conditional E-value: 2.5 VBS 32 eelgglasqltsdygrlasqakmaavaaeneeigaqiktrvqelghgcialvtkagalqvspsdvytkkeliecaravsekvslvl 117 e l +la+ ++ l +ak a a++ e ++ + +e + lv + s s + +++e a+ v+ v FUN_000330-T1 689 EMLLALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATAVDDTE 774 66778999999999999999999999999999999999999999999999999988888888888999999999999988887655 PP == domain 3 score: 6.8 bits; conditional E-value: 0.0086 VBS 12 takaiavtvqemvtksvtspeelgglasqltsd.ygrlasqakmaavaaeneeigaqiktrvqelghgcialvtkagalqvspsdvytkkelie 104 t+k++ ++ +++t + e g+a++ t++ l+ a+ a++a+++ + +++ + q++ + l++ a + p d + l + FUN_000330-T1 1117 TSKTVGSSMAQLLTAASQGNESYTGIAARDTANaLQVLTAAARGVAATADDKALQLNLIKATQDVVAESAKLINEAKSAVNNPGDPGNQPRLAQ 1210 7899999999999999999999999999888772566889999***********************************99************** PP VBS 105 caravsekvs 114 a+ vs+ + FUN_000330-T1 1211 AAKEVSQALN 1220 **99998765 PP == domain 4 score: 16.5 bits; conditional E-value: 8.3e-06 VBS 13 akaiavtvqemvtksvtspeelgglasqltsdygrlasqakmaavaaeneeigaqiktrvqelghgcialvtkagalqvspsdvytkkelieca 106 a+ ++ emv+ s + ++l + +++++s y l + a a++e + + +++ + l+ a +l p +k+ l + a FUN_000330-T1 1269 GAALNAAASEMVSASRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAKDEAAKDSMVRNLKNTSTASSKLLLAAKSLVSDPNAPNAKNSLANAA 1362 56788899********************************9999******999999999*********************************** PP VBS 107 ravsekvslvlaal 120 rav++ + ++l a FUN_000330-T1 1363 RAVTDSINMLLNAC 1376 ********999885 PP == domain 5 score: 6.7 bits; conditional E-value: 0.0091 VBS 33 elgglasqltsdygrlasqakmaavaa..eneeigaqiktrvqelghgcialvtkagalqvspsdvytkkeliecaravsekvslvlaalq 121 l g+ +q+ + ++a + a+aa e+e+i +rv ++ + l +a +d+ k +l++ a++v+e ++++ a + FUN_000330-T1 1717 SLQGFQAQMMQNLIQMADVIDPLATAAksEPENI----GHRVAQMASFISPLTDHAVGAASQMADIQRKVDLLDQAKTVAECAAQLMYATK 1803 4778888898998899888887776661155555....58999999999999999988888899999999999999999999888777765 PP == domain 6 score: 101.2 bits; conditional E-value: 5.3e-32 VBS 2 fvdyqttvvktakaiavtvqemvtksvtspeelgglasqltsdygrlasqakmaavaaeneeigaqiktrvqelghgcialvtkagalqvspsd 95 fv+yq + + k ++ +q+mv ks+t+p +lg+l ++++ y +a +++ a + n ei ++i+t vq lg ci lv+ ga+q d FUN_000330-T1 1879 FVNYQERMTRAMKELTRRAQDMVGKSATDPTKLGPLGKDISRIYNDIAKDTRRAVKTVGNPEISLRIRTGVQGLGEACISLVQSGGAVQSNHKD 1972 9********************************************************************************************* PP VBS 96 vytkkeliecaravsekvslvlaalqagnk 125 ++kkel + +r+v+ekvs++laalq g + FUN_000330-T1 1973 PFSKKELADNSRNVAEKVSHLLAALQQGSR 2002 **************************9976 PP == domain 7 score: 0.4 bits; conditional E-value: 0.8 VBS 2 fvdyqttvvktakaiavtvqemvtksvtspeelgglasqltsdygrlasqakmaavaaenee 63 f d + ++++tak++ ++++v+ +++s + l + a+ la + k a+a +++ FUN_000330-T1 2042 FGDRREAILRTAKTLVEDTKNLVSAAQASQDVLASAAQSAVGSVSSLADNVKLGAIALGSDD 2103 77888888999999999999999999999999888888888888888888888887765544 PP >> FERM_f0 N-terminal or F0 domain of Talin-head FERM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.1 0.0 3e-31 3.9e-28 1 80 [. 3 83 .. 3 84 .. 0.99 2 ? 5.0 0.1 0.033 43 3 53 .. 89 136 .. 88 156 .. 0.90 Alignments for each domain: == domain 1 score: 98.1 bits; conditional E-value: 3e-31 FERM_f0 1 LslkislveknvtKtiqFdpetlvkdacklireKvseael.nakdygLFladedgkksvWlesertleyYdlregdeleYk 80 Lslkis+v+++ +KtiqF+pe++v++a+++ire+v ++ + +dygLF +d+d++k++Wle++rtl++Y l++gd+leYk FUN_000330-T1 3 LSLKISIVKNSAIKTIQFNPEATVAEALRIIRERVHDSTPgKISDYGLFSQDDDPSKGKWLEPARTLNFYPLKNGDMLEYK 83 8**************************************99***************************************9 PP == domain 2 score: 5.0 bits; conditional E-value: 0.033 FERM_f0 3 lkislveknvtKtiqFdpetlvkdacklireKvseaelnakdygLFladed 53 lki++ ++++Kt+q d + v ++ + K+ ++ +++++L ++++ FUN_000330-T1 89 LKIKF-MDGTVKTLQIDDSHNVGQILDSVCVKMGIGN--VEEFSLLVEGQK 136 89999.7899***********************9999..79***9987754 PP >> FERM_M FERM central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.2 0.1 6e-29 7.6e-26 2 117 .] 214 324 .. 213 324 .. 0.97 Alignments for each domain: == domain 1 score: 91.2 bits; conditional E-value: 6e-29 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FERM_M 2 lesklqdevtrellYlQlkrdllegrlpcseeeallLAaLqlqaelgdyssesheseylslesflpkqllkklkskelekrvleahkklrglsaee 97 ++ +++d+v ++ll++Q+++ +l+g +p +++ea++LAa+q+q+++ d++++ + + ++l++flpk+ ksk++ek++ e+hkk++g ++ + FUN_000330-T1 214 QNVDIKDPVQLNLLFVQCRDGILDGTHPITQDEAIQLAAIQIQVQFSDFDDS--KYKFIDLKEFLPKE---YVKSKNIEKKIKEEHKKVSGHDELQ 304 67789*********************************************98..77889********9...999********************** PP xxxxxxxxxxxxxxxxxxxx RF FERM_M 98 AklkylqiaqslptyGvelF 117 k+ky q+++ l+tyGv++F FUN_000330-T1 305 GKYKYVQLCRGLKTYGVTFF 324 *******************9 PP >> FERM_N FERM N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.97 1.2e+03 39 58 .. 49 69 .. 47 72 .. 0.78 2 ! 27.9 0.2 1.8e-09 2.3e-06 1 46 [. 91 136 .. 91 142 .. 0.93 3 ? 2.3 0.1 0.18 2.3e+02 46 63 .. 180 197 .. 174 198 .. 0.85 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.97 FERM_N 39 GLqfldsk.sehrWLdlekkl 58 GL +d++ s+ +WL+++++l FUN_000330-T1 49 GLFSQDDDpSKGKWLEPARTL 69 5666655559********998 PP == domain 2 score: 27.9 bits; conditional E-value: 1.8e-09 FERM_N 1 VrlLDgtklefevqkkatgqelLdqVckhlnlkEkdyFGLqfldsk 46 ++++Dgt+++++++++++++++Ld Vc ++++ +++ F+L + ++k FUN_000330-T1 91 IKFMDGTVKTLQIDDSHNVGQILDSVCVKMGIGNVEEFSLLVEGQK 136 68**************************************999777 PP == domain 3 score: 2.3 bits; conditional E-value: 0.18 FERM_N 46 ksehrWLdlekklekqak 63 ++e WL ++k+l++q++ FUN_000330-T1 180 DDEVQWLGHDKTLREQGV 197 5789************86 PP >> RA_2 RA like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.67 8.5e+02 11 37 .. 12 38 .. 4 53 .. 0.84 2 ! 23.7 0.1 4e-08 5.1e-05 4 49 .. 88 133 .. 85 183 .. 0.90 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.67 RA_2 11 Dgsskavevdsattarevceklaeklg 37 + k++++++ +t++e+++ + e+++ FUN_000330-T1 12 NSAIKTIQFNPEATVAEALRIIRERVH 38 56789***************9999887 PP == domain 2 score: 23.7 bits; conditional E-value: 4e-08 RA_2 4 vvkvflmDgsskavevdsattarevceklaeklglkdsegFsLyes 49 ++k+ +mDg++k++++d + ++++++ ++ k+g+ + e FsL FUN_000330-T1 88 HLKIKFMDGTVKTLQIDDSHNVGQILDSVCVKMGIGNVEEFSLLVE 133 6899**************************************9865 PP >> Vinculin Vinculin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.047 60 772 826 .. 597 647 .. 576 649 .. 0.81 2 ! 6.4 4.6 0.0025 3.2 21 115 .. 674 770 .. 667 773 .. 0.87 3 ! 16.5 6.7 2.3e-06 0.0029 514 657 .. 841 984 .. 821 1028 .. 0.76 4 ? 0.7 2.1 0.14 1.7e+02 382 474 .. 1125 1217 .. 1120 1264 .. 0.75 5 ! 20.2 1.9 1.7e-07 0.00022 31 119 .. 1283 1373 .. 1271 1432 .. 0.86 6 ! 11.4 13.1 7.7e-05 0.098 40 367 .. 1516 1840 .. 1503 1942 .. 0.67 7 ? 3.1 12.1 0.025 32 5 199 .. 2047 2243 .. 2044 2267 .. 0.70 8 ? 2.2 3.3 0.047 59 17 90 .. 2432 2505 .. 2419 2510 .. 0.73 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.047 Vinculin 772 IalictQLkilSkVKAtvlglsnelvvedldaaesLvqnAkNLmqsVketVkaae 826 I +i+ L+ lSk ++ +++ l ++d+d+ +sL+ +A+NL + + kaa+ FUN_000330-T1 597 INTISSNLQDLSK---GIKMIAG-LLDDDDDTSKSLLDAARNLAGAFSNLLKAAQ 647 6666666666666...3445555.8899999************999999999885 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0025 Vinculin 21 Lvilheeaekdkgavkdltalvaavekavenlikkgeeiakesdd..lkedlpaAleeVekagelleeaaselaeDpySsvkRkkliegaRglLsa 114 L + e e+d+ + l al++av +a++ l+ k ++ia+e dd ++++ +A +e ++ +l++ + + S + ++++e+a+ + +a FUN_000330-T1 674 LLQFMGEPEVDQRTQEMLLALAQAVANATAALVLKAKNIASEADDteNQNKVINAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATA 769 555666889999999******************************888889999999999999999988888887777888899999999877777 PP Vinculin 115 v 115 v FUN_000330-T1 770 V 770 6 PP == domain 3 score: 16.5 bits; conditional E-value: 2.3e-06 Vinculin 514 adpetlvatassiarranRvllvvkaEmdnseepvytervkeAakeLkktvvpmvaeakevavnaldaeaaksveesneelldavr.lVrdavrdi 608 ++ ++v++a +a ++ +++ +kaE++ +++ ++r+++Aak+L ++ + v+ ak +a n++ a+++++++++ e+l +a + da+++ FUN_000330-T1 841 GNAGEMVKQAKILAQASSSLVTGIKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKGAAKNPNAADQQQKLKQAAEDLRSATNaAASDALKKK 936 577899***************************************************************************999851568999865 PP Vinculin 609 rkavlmnrlpeeletdseleiqedeeadvrskssvetedelrqiseeet 657 l ++e + ++++l ++ a + ++++ +++ +q ++ e+ FUN_000330-T1 937 LVRRLEVASKEAAGQATQLI-AAAQMAGPSNRNQTSQQQLDDQCKPVEE 984 55555555666666666555.4444444444333333332233333333 PP == domain 4 score: 0.7 bits; conditional E-value: 0.14 Vinculin 382 lkllieAakagrEeeveekakvfqehanklvevarlaasvsknketveliraaaaqveeLtPQvinAarillanpgskaaqenletlknqwed 474 + +l Aa +g+E + a+ + + l++ ar +a+ +++k + +a + v + + +in a+ ++npg+ +q l + ++ ++ FUN_000330-T1 1125 MAQLLTAASQGNESYTGIAARDTANALQVLTAAARGVAATADDKALQLNLIKATQDVVAESAKLINEAKSAVNNPGDPGNQPRLAQAAKEVSQ 1217 567888999999998888888888888888889999998888877666666666777777888999999999999888887777655554444 PP == domain 5 score: 20.2 bits; conditional E-value: 1.7e-07 Vinculin 31 dkgavkdltalvaavekavenlikkgeeiakesdd..lkedlpaAleeVekagelleeaaselaeDpySsvkRkkliegaRglLsavsrLL 119 +g +++l a +++ + + l+ g + a + +d +k+ ++ l++ a+++l aa++l +Dp +++++l ++aR++ ++ LL FUN_000330-T1 1283 SRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAKDeaAKDSMVRNLKNTSTASSKLLLAAKSLVSDPNAPNAKNSLANAARAVTDSINMLL 1373 6889999***********************99888899*********************************************99887776 PP == domain 6 score: 11.4 bits; conditional E-value: 7.7e-05 Vinculin 40 alvaavekavenlikkgeeiakesdd..lkedlpaAleeVekagelleeaaselaeDpySsvkRkkliegaRglLsavsrLLllaDeadVrkii 131 ++ av k ++ l + ++ ++++ +k+++++A ++V +++ +l++ ++ la D +S R+ e++R l+++v +L a + + + FUN_000330-T1 1516 GAATAVAKHTSALCNACKAASAKTNNpaAKRQFVQAAKDVANNTANLVKNTKILAGD-MSEANREACAEATRPLMNSVESLTAYALSPEFAPLR 1608 4567788888888888887665555557***************************99.7999********************999999998886 PP Vinculin 132 rklkkvedylavaevietkedlvqlvkdlspeleklakevakRqqeLtdqehrdelvaarealkklapiLitamkvfvrhp.gveeareNRdyl 224 k+ ++++ a+v l k++ ++ + +++ + + +dq ++l+ +a+ + Lita k + + +ea e +y+ FUN_000330-T1 1609 AKI---SEEARSAQV-----PLIMSGKSMATSSTNYFNVAKALAVNSKDQPGWQQLALQAKAVSDAMRRLITAIKDNAPGQrECDEALEQINYT 1694 554...444444433.....455566677777777777777777788899999999999999*************9988866************ PP Vinculin 225 vkrmsde.lneiirvlqltsytvakkalsaigseLaaaldelddkii.....ldpaekseerarpeleeriesiiseaasmadslctlrnrrq. 311 ++++ ++ l++i++vl+ + ++ + ++++ ++L++ d +d + +++ ++ ++++ + + + +a++mad + + + q FUN_000330-T1 1695 INQLDQAsLAAISQVLEPRPENSLQGFQAQMMQNLIQMADVIDPLATaaksePENIGHRVAQMASFISPLTDHAVGAASQMADIQRKVDLLDQa 1788 ****87549********99976666666655556666555554443322122333333333333344445556666677777777777766666 PP Vinculin 312 aivaelng...........................avrqAlqdllseyrklagrkedldalcsaidrarkktkdLrrqlrkav 367 ++vae+ ++++ kdL ++l +a FUN_000330-T1 1789 KTVAECAAqlmyatkegggnpkfveadpaiseaaqG-------------------------------MKEAVKDLSHTLEEAA 1840 778888854444444444455555555544444442...............................5555555554444442 PP == domain 7 score: 3.1 bits; conditional E-value: 0.025 Vinculin 5 ktvekileplvqqvsrLvilheeaekdkgavkdltalvaavekavenlikkgeeiakesdd..lkedlpaAleeVekagelleeaaselaeDpy 96 ++ ++ + lv++ +Lv + ++ ++ +v++v+ +n +k g ia sdd +++ l++A ++V +a +l +a+++ + ++ FUN_000330-T1 2047 EAILRTAKTLVEDTKNLVSAAQASQ--DVLASAAQSAVGSVSSLADN-VKLGA-IALGSDDsdAQQMLLNAAKDVASALGALINATKNASGKSV 2136 678889999999999***9998777..5666778999*****99888.79999.776666668******************************* PP Vinculin 97 SsvkRkkliegaRglLsavsrLLllaDeadVrkiirklkkvedylavaevi.....etkedlvq.lvkdlspeleklakevakRqqeLtdqehr 184 S ++ ++l +++ + vs+LL + +++ + +r + e ++++++++ ++ + + + dl++ ++++ +++ + h+ FUN_000330-T1 2137 SDPAMEELKTTGKTMVANVSSLLKTVKSVEDK-ALRGTRALESTVDAVKQAvlemqSSSMPVRDaTPEDLIRSTKDVTLAT-AKAVAAGNSCHQ 2228 ***************************99955.566666666666655543110002222222202344555555554333.333444455555 PP Vinculin 185 delvaarealkklap 199 d+++ a ++ +k ++ FUN_000330-T1 2229 DDIITAANMGRKAVT 2243 666666666555555 PP == domain 8 score: 2.2 bits; conditional E-value: 0.047 Vinculin 17 qvsrLvilheeaekdkgavk.dltalvaavekavenlikkgeeiakesddlkedlpaAleeVekagelleeaase 90 ++L + a ++++a++ +l a + +v++++++l+ ++ a+++ ++ l++A ++V+ka+++l++aa++ FUN_000330-T1 2432 ATTTLCDAAN-AAVQGNASEeRLIAGAKQVSNSTAQLLLACRVKADSNSVTQRRLQTAGNAVKKAADNLVTAAKN 2505 4566666654.4446666642677888889999999999999878888888889999999999999999888875 PP >> DUF1657 Protein of unknown function (DUF1657) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.1 0.0034 4.4 15 40 .. 1532 1557 .. 1528 1563 .. 0.85 2 ? -2.6 0.0 5.8 7.5e+03 32 46 .. 1819 1833 .. 1814 1834 .. 0.88 3 ! 6.3 0.0 0.0098 13 19 40 .. 2098 2119 .. 2094 2124 .. 0.91 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0034 DUF1657 15 LetFAlqTqdeeAkqmYeqaaeqlee 40 ++ + T+++ Ak+ + qaa+++ + FUN_000330-T1 1532 CKAASAKTNNPAAKRQFVQAAKDVAN 1557 6667889***************9976 PP == domain 2 score: -2.6 bits; conditional E-value: 5.8 DUF1657 32 eqaaeqleeviqdLe 46 ++aa+ ++e ++dL FUN_000330-T1 1819 SEAAQGMKEAVKDLS 1833 79***********96 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0098 DUF1657 19 AlqTqdeeAkqmYeqaaeqlee 40 Al ++d A+qm+ +aa+++ + FUN_000330-T1 2098 ALGSDDSDAQQMLLNAAKDVAS 2119 99****************9876 PP >> DdMyo7_FERM DdMyo7 FERM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.1 1.6e-05 0.02 9 82 .. 216 288 .. 210 299 .. 0.83 2 ? -2.8 0.1 9.5 1.2e+04 27 66 .. 1686 1726 .. 1684 1734 .. 0.66 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.6e-05 DdMyo7_FERM 9 lwtddeisfeltfvqireewlrglyltlsekdisvaaailiqlaypnqsklqltkellrqvlpdqllnsqnikf 82 + +d + ++l fvq r+ l g++ +++ ++ +aai iq+++ + + + l+++lp++ ++s+ni FUN_000330-T1 216 VDIKDPVQLNLLFVQCRDGILDGTHP-ITQDEAIQLAAIQIQVQFSDFDDSKYKFIDLKEFLPKEYVKSKNIEK 288 55689999*****************9.8888888999999999998765555555569*************975 PP == domain 2 score: -2.8 bits; conditional E-value: 9.5 DdMyo7_FERM 27 ewlrglyltlsekdisvaaailiqla.ypnqsklqltkell 66 e l + t+++ d + +aai l+ p++s ++ +++ FUN_000330-T1 1686 EALEQINYTINQLDQASLAAISQVLEpRPENSLQGFQAQMM 1726 666777778******99999975554244555444555555 PP >> TrcR Transcriptional cell cycle regulator TrcR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.18 2.3e+02 103 125 .. 205 227 .. 195 233 .. 0.87 2 ? 9.9 0.1 0.00079 1 36 108 .. 284 356 .. 272 365 .. 0.83 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.18 TrcR 103 irdrthwnsanikpkdPvtlglc 125 +r + +++ +n++ kdPv+l+l FUN_000330-T1 205 LRRKYFYSDQNVDIKDPVQLNLL 227 6899999*************985 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00079 TrcR 36 kdenarlklkesklelaekkkkgarYtPvskRqdrPdaiawllrnhpelkdaqiaklvgttketieairdrth 108 k+ ++++k +++k++ +++ + + +Y+ + + +l+++ + k++ + +l+g tke+i ++ ++t+ FUN_000330-T1 284 KNIEKKIKEEHKKVSGHDELQGKYKYVQLCRGLKTYGVTFFLVKEKMKGKNKLVPRLLGVTKESILRVDEKTK 356 56666777777777777677777799999988888888889***************************99987 PP >> PUB PUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 5.8e-05 0.074 12 59 .. 2280 2327 .. 2277 2349 .. 0.86 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 5.8e-05 PUB 12 lkyleNilsnpneekyRkirlsNkafqekvlplegalelLeaiGFeek 59 l ++ Ni ++p++ek +k+ ++k++ ++v++l a e L+ + +++ FUN_000330-T1 2280 LDLVHNITQKPTQEKKQKLTPQSKMIADQVAKLVHAAEALKGVNWVNP 2327 56899***********************************99988764 PP >> DUF7783 Domain of unknown function (DUF7783) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.9 1 1.3e+03 68 119 .. 690 741 .. 680 772 .. 0.79 2 ? 12.0 2.6 0.00016 0.21 35 114 .. 843 925 .. 833 937 .. 0.82 3 ? 3.4 0.1 0.074 95 24 113 .. 968 1053 .. 954 1067 .. 0.79 4 ? 13.3 0.1 6.8e-05 0.087 10 119 .. 1119 1224 .. 1116 1233 .. 0.89 5 ? 3.5 2.1 0.071 91 24 122 .. 1283 1377 .. 1272 1385 .. 0.71 6 ? 1.2 0.6 0.37 4.7e+02 81 122 .. 1526 1567 .. 1493 1597 .. 0.73 7 ? -1.3 0.0 2.1 2.7e+03 29 51 .. 1654 1676 .. 1643 1709 .. 0.71 8 ? -2.3 0.0 4.4 5.6e+03 13 50 .. 1766 1803 .. 1761 1830 .. 0.76 9 ? -1.5 0.1 2.5 3.2e+03 45 92 .. 2025 2072 .. 1982 2098 .. 0.50 10 ? -0.1 0.2 0.96 1.2e+03 67 125 .. 2072 2132 .. 2038 2137 .. 0.60 11 ? 1.2 0.1 0.37 4.7e+02 27 84 .. 2106 2159 .. 2101 2165 .. 0.66 12 ? 3.6 0.0 0.068 87 12 51 .. 2279 2318 .. 2276 2342 .. 0.80 13 ? 3.5 0.9 0.073 93 39 124 .. 2423 2506 .. 2416 2512 .. 0.60 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1 DUF7783 68 aLkphhralmaslsKLvLsskvAsgvwpppdavakllqeadevlvaVrnFve 119 L + +a+ ++ + LvL +k ++ ++ +k+ ++a+e + v+ FUN_000330-T1 690 MLLALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVA 741 5555556667778889999998888888899999999999987766666555 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00016 DUF7783 35 aeaiveairllLaagsgtt...dkesgessiiksnkaLkphhralmaslsKLvLsskvAsgvwpppdavakllqeadevlvaV 114 a ++v++ ++l a+s+ + + e++++ s+k L + + l + +KLv ++k A+++ +++d+ +kl+q+a+++ +a FUN_000330-T1 843 AGEMVKQAKILAQASSSLVtgiKAEAETQDDSDSQKRLLAAAKVLADATAKLVEAAKGAAKNPNAADQQQKLKQAAEDLRSAT 925 566777777777776654312255666677788999999999************************************98775 PP == domain 3 score: 3.4 bits; conditional E-value: 0.074 DUF7783 24 kngqkeeyvekaeaiveairllLaagsgttdkesgessiiksnkaLkphhralmaslsKLvLsskvAsgvwpppdavakllqeadevlva 113 ++++++++ ++ + + e+i l+ + ++ +++ + + + aL + +++++ sKLv sk A ++ p ++++l + a+ ++ FUN_000330-T1 968 NQTSQQQLDDQCKPVEESINHLVESLKE----TGRNPDVAAPQLALINTSKEFIQPTSKLVANSKAALPTIGDPITATQLANFAKSTATS 1053 4667788888889999999999998443....3457899999************************988888777777777766665555 PP == domain 4 score: 13.3 bits; conditional E-value: 6.8e-05 DUF7783 10 ediaqaieelneaikngqkeeyvekaeaiveairllLaagsgttdkesgessiiksnkaLkphhralmaslsKLvLsskvAsgvwpppdavakl 103 +++ +++ +l +a+ +g++++ a++ +a+++l aa+ g++ + + ++++ +L + ++++a+ +KL+ +k A ++ p + +l FUN_000330-T1 1119 KTVGSSMAQLLTAASQGNESYTGIAARDTANALQVLTAAARGVAATA--DDKALQ--LNLIKATQDVVAESAKLINEAKSAVNNPGDPGNQPRL 1208 67788999***********99999***************99987654..345555..5689999****************************** PP DUF7783 104 lqeadevlvaVrnFve 119 q+a+ev +a++n v+ FUN_000330-T1 1209 AQAAKEVSQALNNCVN 1224 **********999876 PP == domain 5 score: 3.5 bits; conditional E-value: 0.071 DUF7783 24 kngqkeeyvekaeaiveairllLaagsgttdkesgessiiksnkaLkphhralmaslsKLvLsskvAsgvwpppdavakllqeadevlvaVrnF 117 +g+ +++ +++++ + + + lL +g + + + + +++ +++ ++ ++ sKL L++k ++ ++p+a + l ++a+ v +++ FUN_000330-T1 1283 SRGTSNQLAASTKKFSSSYQDLLDSGMKLAGQAK---DEAAKDSMVRN-LKNTSTASSKLLLAAKSLVSDPNAPNAKNSLANAARAVTDSINML 1372 5566666666777777777777776554443332...22333334443.466667789*******99999999***********9999999988 PP DUF7783 118 vevaq 122 ++++ FUN_000330-T1 1373 LNACM 1377 88876 PP == domain 6 score: 1.2 bits; conditional E-value: 0.37 DUF7783 81 sKLvLsskvAsgvwpppdavakllqeadevlvaVrnFvevaq 122 s L + k As+ +++p a + q+a++v + n v+ + FUN_000330-T1 1526 SALCNACKAASAKTNNPAAKRQFVQAAKDVANNTANLVKNTK 1567 445556677777777777777777777777777666665544 PP == domain 7 score: -1.3 bits; conditional E-value: 2.1 DUF7783 29 eeyvekaeaiveairllLaagsg 51 +++ +a+a+++a+r l++a + FUN_000330-T1 1654 QQLALQAKAVSDAMRRLITAIKD 1676 56667899999999999999443 PP == domain 8 score: -2.3 bits; conditional E-value: 4.4 DUF7783 13 aqaieelneaikngqkeeyvekaeaiveairllLaags 50 +a+ + +++ + k ++ ++a+++ e l++a++ FUN_000330-T1 1766 DHAVGAASQMADIQRKVDLLDQAKTVAECAAQLMYATK 1803 67788888899999999999999999999999999953 PP == domain 9 score: -1.5 bits; conditional E-value: 2.5 DUF7783 45 lLaagsgttdkesgessiiksnkaLkphhralmaslsKLvLsskvAsg 92 +L a+ gt++ e + s+ + +a+ ++l+ Lv +++ + + FUN_000330-T1 2025 VLFAATGTLQPEVEGDSFGDRREAILRTAKTLVEDTKNLVSAAQASQD 2072 455556666655555555555555555555555555555533333333 PP == domain 10 score: -0.1 bits; conditional E-value: 0.96 DUF7783 67 kaLkphhralmaslsKLvLsskvAsgvwpp..pdavakllqeadevlvaVrnFvevaqelr 125 L + ++ + s+s L k+ + + + da + ll++a++v +a+ +++ ++++ FUN_000330-T1 2072 DVLASAAQSAVGSVSSLADNVKLGAIALGSddSDAQQMLLNAAKDVASALGALINATKNAS 2132 4455555555555555555555555544431156777888888888888888887777665 PP == domain 11 score: 1.2 bits; conditional E-value: 0.37 DUF7783 27 qkeeyvekaeaiveairllLaagsgttdkesgessiiksnkaLkphhralmaslsKLv 84 ++ + + a+++ a+ l+ a+++ sg+s + ++Lk+ ++++a++s L FUN_000330-T1 2106 AQQMLLNAAKDVASALGALINATKNA----SGKSVSDPAMEELKTTGKTMVANVSSLL 2159 45667778888888888888885444....4434444455678888888888887764 PP == domain 12 score: 3.6 bits; conditional E-value: 0.068 DUF7783 12 iaqaieelneaikngqkeeyvekaeaiveairllLaagsg 51 + +++ ++ +++k++++++++ i +++ l++a+++ FUN_000330-T1 2279 MLDLVHNITQKPTQEKKQKLTPQSKMIADQVAKLVHAAEA 2318 556799999999999****************999999654 PP == domain 13 score: 3.5 bits; conditional E-value: 0.073 DUF7783 39 veairllLaagsgttdkesgessiiksnkaLkphhralmaslsKLvLsskvAsgvwpppdavakllqeadevlvaVrnFvevaqel 124 v a r++ aa+ d ++ + +s++ L + +++ +s ++L L+ +v ++ + +l+++ + v a n v++a+++ FUN_000330-T1 2423 VSAARMVAAATTTLCDAANAAVQGNASEERLIAGAKQVSNSTAQLLLACRVKADSN--SVTQRRLQTAGNAVKKAADNLVTAAKNA 2506 55566666666555665555555556666666666666666666666666666543..3344566666666666666666666665 PP >> URGCP Up-regulator of cell proliferation-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 1.3 0.00013 0.17 204 292 .. 692 780 .. 674 786 .. 0.81 2 ? 7.2 3.4 0.0029 3.8 156 297 .. 838 987 .. 826 990 .. 0.74 3 ? -3.7 0.2 6.2 7.9e+03 194 242 .. 2458 2506 .. 2444 2539 .. 0.76 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00013 URGCP 204 ilvlsekekkkkeelealkkllkelelkkkkvliklknrneaelveelkkaikkvlskskkkvsleelaeiarelgikvDedseecqka 292 + + ++ ++ ++ + + k++++e + ++++ ++ + +++ a+++ +l + +k v+ + ++++ e+++e a+ + vD+ +++c++a FUN_000330-T1 692 LALAQAVANATAALVLKAKNIASEADDTENQNKVINAAKETARTTAQLVACVKVVVPSISSHMCQEQVVEAAKLVATAVDDTESACKEA 780 333333344444445567778888888888888889999************************************************97 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0029 URGCP 156 NLrGdaeshekqlsfLtevSsvvvvlldkldeke......kkllkslk...kskkklilvlsekekkkkeelealkkllkelelkkkkvliklknr 242 N G+a ++ kq ++L ++Ss +v ++ e++ k+ll+ k ++++kl+ + +k+ +++++ +kl ++ e ++ + +++ FUN_000330-T1 838 NSMGNAGEMVKQAKILAQASSSLVTGIKAEAETQddsdsqKRLLAAAKvlaDATAKLVEAAKGAAKN-PNAADQQQKLKQAAEDLRSATNAAASDA 932 667******************9999887433322233465667766551114444555555444444.4567788888888888899999999999 PP URGCP 243 neaelveelkkaikkvlskskkkvsleelaeiarelgikvDedseecqkakekae 297 +++lv++l+ a k+ + ++ + +++a +++ + + + +++c+ +e+++ FUN_000330-T1 933 LKKKLVRRLEVASKEAAGQATQLIAAAQMAGPSNRNQTSQQQLDDQCKPVEESIN 987 999*********9*99999999999999999888888887777777877666655 PP == domain 3 score: -3.7 bits; conditional E-value: 6.2 URGCP 194 kslkkskkklilvlsekekkkkeelealkkllkelelkkkkvliklknr 242 k++++s+++l+l + k+++++ ++++l++ +++++ ++++ +kn FUN_000330-T1 2458 KQVSNSTAQLLLACRVKADSNSVTQRRLQTAGNAVKKAADNLVTAAKNA 2506 5677788888888888888888888888888888888888887776554 PP >> Serine_rich Serine rich protein interaction domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.2 5.2 6.6e+03 7 46 .. 688 727 .. 684 749 .. 0.62 2 ? 4.4 0.5 0.036 46 12 120 .. 793 904 .. 787 930 .. 0.72 3 ? -0.6 0.3 1.2 1.6e+03 73 100 .. 966 993 .. 906 999 .. 0.56 4 ? 5.0 0.2 0.023 30 53 111 .. 1148 1204 .. 1124 1246 .. 0.70 5 ? -1.8 0.1 2.9 3.7e+03 6 28 .. 1354 1376 .. 1288 1404 .. 0.66 6 ? 2.2 0.1 0.17 2.1e+02 123 150 .. 1651 1678 .. 1572 1707 .. 0.65 7 ? 4.9 0.1 0.025 31 121 153 .. 2041 2074 .. 1976 2077 .. 0.80 8 ? 6.6 0.2 0.0075 9.6 4 55 .. 2138 2193 .. 2136 2197 .. 0.88 9 ? 3.9 0.0 0.052 66 66 108 .. 2282 2324 .. 2232 2336 .. 0.80 10 ? -0.1 0.9 0.88 1.1e+03 7 65 .. 2450 2512 .. 2444 2563 .. 0.61 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 5.2 Serine_rich 7 letlarlqqevessvskLlsfvsskWRsrenleknlqeir 46 e+l +l q+v+++ + L+ +++ + e++ + i+ FUN_000330-T1 688 QEMLLALAQAVANATAALVLKAKNIASEADDTENQNKVIN 727 5788999999999999998776644444444444333333 PP == domain 2 score: 4.4 bits; conditional E-value: 0.036 Serine_rich 12 rlqqevessvskLlsfvsskWRsrenl...eknlqeirkavdkveeslrefleFargavanaaklsdknLqtkLkkqlqkledsyqilletsqaLd 104 q v +++++Ll v + R +++ +++ ++i a+d++ +s+ + e ++a+ a+ s+ k + + q+ +ds++ ll +++ L FUN_000330-T1 793 TAAQGVRDALNNLLIKVREGGRDNQQAgqyDETCDDILGATDRLFNSMGNAGEMVKQAKILAQASSSLVTGIKAEAETQDDSDSQKRLLAAAKVLA 888 556788888888888888777776655444888899999999999999999999999988888777666667777777777888888888888887 PP Serine_rich 105 scgWsldvlatdkkqe 120 + +l + a+ +++ FUN_000330-T1 889 DATAKLVEAAKGAAKN 904 7766665555555544 PP == domain 3 score: -0.6 bits; conditional E-value: 1.2 Serine_rich 73 lsdknLqtkLkkqlqkledsyqillets 100 ++++ q++L +q +++e+s + l+e+ FUN_000330-T1 966 NRNQTSQQQLDDQCKPVEESINHLVESL 993 3345556666666666666655555443 PP == domain 4 score: 5.0 bits; conditional E-value: 0.023 Serine_rich 53 eeslrefleFargavanaaklsdknLqtkLkkqlqkl.edsyqilletsqaLdscgWsld 111 ++l+ ++ arg+ aa + dk Lq L k q++ +s +++ e+++a ++ g + FUN_000330-T1 1148 ANALQVLTAAARGV---AATADDKALQLNLIKATQDVvAESAKLINEAKSAVNNPGDPGN 1204 45555555555555...55667*********99998527999999999999998765444 PP == domain 5 score: -1.8 bits; conditional E-value: 2.9 Serine_rich 6 AletlarlqqevessvskLlsfv 28 A++ la+ ++v++s++ Ll+ FUN_000330-T1 1354 AKNSLANAARAVTDSINMLLNAC 1376 44444444444444444444444 PP == domain 6 score: 2.2 bits; conditional E-value: 0.17 Serine_rich 123 ddldrlvmvartvpdDikqlasiiqana 150 +l a++v+d +++l + i+ na FUN_000330-T1 1651 PGWQQLALQAKAVSDAMRRLITAIKDNA 1678 3444555556666666666666665554 PP == domain 7 score: 4.9 bits; conditional E-value: 0.025 Serine_rich 121 k.pddldrlvmvartvpdDikqlasiiqanaklL 153 + d + ++ +a+t+ +D+k l+s qa+ ++L FUN_000330-T1 2041 SfGDRREAILRTAKTLVEDTKNLVSAAQASQDVL 2074 2578889999****************99988776 PP == domain 8 score: 6.6 bits; conditional E-value: 0.0075 Serine_rich 4 dsAletlarlqqevessvskLlsfvssk....WRsrenleknlqeirkavdkvees 55 d A+e l+ + +++ +vs+Ll+ v+s R le++++++++av ++++s FUN_000330-T1 2138 DPAMEELKTTGKTMVANVSSLLKTVKSVedkaLRGTRALESTVDAVKQAVLEMQSS 2193 789*******************99965334449*****************999877 PP == domain 9 score: 3.9 bits; conditional E-value: 0.052 Serine_rich 66 avanaaklsdknLqtkLkkqlqkledsyqilletsqaLdscgW 108 +v n ++ ++ ++kL +q + + d+ l+++++aL+ +W FUN_000330-T1 2282 LVHNITQKPTQEKKQKLTPQSKMIADQVAKLVHAAEALKGVNW 2324 455556666667789**************************** PP == domain 10 score: -0.1 bits; conditional E-value: 0.88 Serine_rich 7 letlarlqqevessvskLlsfv....sskWRsrenleknlqeirkavdkveeslrefleFarg 65 e+l + ++v++s ++Ll s+ ++ +l++ ++++ka+d++ ++ ++ + F ++ FUN_000330-T1 2450 EERLIAGAKQVSNSTAQLLLACrvkaDSNSVTQRRLQTAGNAVKKAADNLVTAAKNAAIFEEQ 2512 567777788888888888876522123344445666666677777777777776666655543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2564 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2212 (0.0865923); expected 510.9 (0.02) Passed bias filter: 737 (0.028851); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 30 (0.0011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.87u 0.39s 00:00:01.26 Elapsed: 00:00:00.46 # Mc/sec: 22444.72 // Query: FUN_000331-T1 [L=104] Description: FUN_000331 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-11 44.2 0.0 2.8e-11 43.9 0.0 1.1 1 Death Death domain ------ inclusion threshold ------ 0.18 12.5 0.0 0.23 12.2 0.0 1.1 1 Death_Lrrd1 Lrrd1 death domain Domain annotation for each model (and alignments): >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.9 0.0 2.2e-15 2.8e-11 8 72 .. 14 78 .. 11 90 .. 0.89 Alignments for each domain: == domain 1 score: 43.9 bits; conditional E-value: 2.2e-15 Death 8 ldaveplgkdWreLarklglseeeideiesenrdlrsqtyelLklWearegknatvgnLleaLrk 72 l +lg++W++L r lg++e i+ ie+enr++ + +y+ L lW++ g+ at++ L + L++ FUN_000331-T1 14 LSLSGELGSKWKNLSRALGIPEASIEVIEEENRRVVEKCYSSLILWKQGRGSLATYEVLEAGLCH 78 5555679****************************************************999985 PP >> Death_Lrrd1 Lrrd1 death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 1.8e-05 0.23 20 66 .. 27 73 .. 21 84 .. 0.82 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.8e-05 Death_Lrrd1 20 lcqKLklkkseikvlekstlkleEkvyqalekWkteknlsltaaalr 66 l + L + ++ i+v+e+ + ++ Ek y +l Wk+ + + t +l+ FUN_000331-T1 27 LSRALGIPEASIEVIEEENRRVVEKCYSSLILWKQGRGSLATYEVLE 73 66778899999***********************9976655555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 626 (0.0245058); expected 510.9 (0.02) Passed bias filter: 596 (0.0233314); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1033.48 // Query: FUN_000332-T1 [L=112] Description: FUN_000332 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.061 13.6 0.0 0.098 12.9 0.0 1.3 1 CSTF1_dimer Cleavage stimulation factor subunit 1, dimerisat 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 DUF6400 Family of unknown function (DUF6400) Domain annotation for each model (and alignments): >> CSTF1_dimer Cleavage stimulation factor subunit 1, dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 7.7e-06 0.098 2 21 .. 18 37 .. 17 40 .. 0.93 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 7.7e-06 CSTF1_dimer 2 aikeRelLYRliIsQLfyDG 21 +ik+ e+LYR +QL +DG FUN_000332-T1 18 SIKSQERLYRGYSQQLIADG 37 79*****************9 PP >> DUF6400 Family of unknown function (DUF6400) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 1.8e-05 0.23 1 43 [. 46 89 .. 46 103 .. 0.82 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 1.8e-05 DUF6400 1 FevdltaeEarRr.aevlaalgddwDPvavlrgEeeAydlLYSg 43 F++ l++eE +R+ ++l lgddw a l +E eA+ L g FUN_000332-T1 46 FKLFLANEENKRQlCQLLLSLGDDWSVGAELIDELEAFTCLMYG 89 677788999999846999******************99866444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (112 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 390 (0.0152672); expected 510.9 (0.02) Passed bias filter: 362 (0.0141711); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1151.14 // Query: FUN_000334-T1 [L=1535] Description: FUN_000334 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-107 351.1 9.5 4.3e-16 59.4 0.0 7.7 8 TPR_12 Tetratricopeptide repeat 5.7e-99 320.8 47.1 6.6e-08 32.5 0.1 13.9 13 TPR_1 Tetratricopeptide repeat 2.2e-67 217.9 9.4 1.9e-05 24.9 0.0 13.8 13 TPR_7 Tetratricopeptide repeat 5e-67 217.0 48.8 2.1e-05 24.8 0.1 14.4 14 TPR_2 Tetratricopeptide repeat 1.9e-63 205.7 44.7 3.9e-05 23.9 0.0 13.2 12 TPR_8 Tetratricopeptide repeat 3.3e-39 132.2 5.2 0.056 14.0 0.0 12.5 12 TPR_10 Tetratricopeptide repeat 5.9e-33 111.7 0.2 0.52 11.6 0.0 13.4 12 TPR_6 Tetratricopeptide repeat 3.1e-32 110.5 51.7 0.036 14.2 0.1 16.7 15 TPR_11 TPR repeat 4.8e-30 105.5 39.6 6.4e-10 39.4 2.2 4.5 6 SNAP Soluble NSF attachment protein, SNAP 1.4e-24 86.7 0.3 0.025 15.5 0.0 10.6 11 TPR_16 Tetratricopeptide repeat 1.1e-21 75.7 0.9 0.86 10.5 0.0 12.4 10 TPR_17 Tetratricopeptide repeat 2.3e-19 70.2 11.5 12 6.7 0.1 13.1 12 DUF7018 Domain of unknown function (DUF7018) 1e-17 65.0 0.0 4.3e-05 23.4 0.0 5.1 6 TPR_MalT MalT-like TPR region 4.1e-17 61.4 3.0 3.9 9.0 0.0 11.8 10 TPR_14 Tetratricopeptide repeat 1.2e-16 61.4 2.7 3.4e-16 59.9 2.7 1.8 1 COR-A C-terminal of Roc, COR-A domain 8.3e-14 52.3 0.6 6.8e-06 26.8 0.0 3.0 2 Roc Ras of Complex, Roc, domain of DAPkinas 4.3e-13 49.9 4.0 0.35 11.0 0.0 8.7 8 ComR_TPR ComR tetratricopeptide 1.1e-12 48.3 0.1 7.2 7.2 0.0 9.5 9 TPR_9 Tetratricopeptide repeat 1.4e-09 38.5 15.7 17 5.7 0.1 10.7 11 DUF7380 Domain of unknown function (DUF7380) 2.2e-09 37.0 22.9 0.49 9.4 0.4 7.4 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.7e-07 31.1 14.8 36 4.5 0.0 10.3 9 SHNi-TPR SHNi-TPR 7.7e-07 29.4 0.0 28 4.8 0.0 6.7 8 TPR_COPA_B COPA/B TPR domain 8.4e-07 29.2 11.2 55 4.2 0.0 10.0 10 TP6A_N Type IIB DNA topoisomerase 3.8e-06 27.2 18.1 1.2 9.3 0.4 7.8 9 RPN7 26S proteasome subunit RPN7 8.8e-05 23.0 18.2 36 4.7 0.1 10.9 12 CoV_NSP8 Coronavirus replicase NSP8 0.00038 21.0 10.2 26 5.5 0.1 8.3 8 ANAPC5 Anaphase-promoting complex subunit 5 0.00043 21.0 12.0 14 6.4 0.2 8.6 8 ARM_TT21_4th Tetratricopeptide repeat protein 21 for 0.00049 20.2 0.0 0.76 9.8 0.0 2.5 2 Ras Ras family 0.0034 17.9 0.0 0.0082 16.7 0.0 1.7 1 Death Death domain 0.0072 16.5 7.7 22 5.1 0.1 5.1 5 Phage_tail_tube_init Putative phage tail tube initiator prot ------ inclusion threshold ------ 0.015 14.2 0.3 4.4 6.0 0.1 3.6 4 Cohesin_load Cohesin loading factor 0.02 15.3 2.0 9 6.6 0.1 4.3 5 HEAT_Nup120 Nucleoporin Nup120, HEAT repeats 0.097 13.0 0.0 0.37 11.1 0.0 2.0 1 PduV-EutP Ethanolamine utilisation - propanediol 0.16 12.3 1.3 3.3e+02 1.5 0.0 5.4 4 RE_NgoFVII_C NgoFVII C-terminal B3-like DNA-binding 0.23 11.6 0.0 1.8e+02 2.3 0.0 3.9 4 DMA DMRTA motif 0.23 12.7 0.0 47 5.5 0.0 3.4 2 TPR_4 Tetratricopeptide repeat 0.44 11.1 3.1 96 3.5 0.0 5.3 7 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.3 0.0 1.3e-13 9e-11 19 77 .] 24 80 .. 22 80 .. 0.96 2 ! 59.4 0.0 6.2e-19 4.3e-16 6 77 .] 91 160 .. 86 160 .. 0.96 3 ! 54.7 0.0 1.8e-17 1.2e-14 5 77 .] 170 240 .. 167 240 .. 0.96 4 ! 50.0 0.1 5.1e-16 3.5e-13 5 77 .] 250 320 .. 249 320 .. 0.96 5 ! 50.7 0.0 3.2e-16 2.2e-13 4 77 .] 289 360 .. 286 360 .. 0.93 6 ! 49.9 0.0 5.6e-16 3.9e-13 6 77 .] 331 400 .. 327 400 .. 0.96 7 ! 50.7 0.0 3.2e-16 2.2e-13 4 77 .] 369 440 .. 366 440 .. 0.93 8 ! 56.6 0.0 4.4e-18 3e-15 6 77 .] 451 520 .. 446 520 .. 0.96 Alignments for each domain: == domain 1 score: 42.3 bits; conditional E-value: 1.3e-13 TPR_12 19 ydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++eAl +ek l +a+++ +d+ ++ +a+ nLg++y+ d+ +A+e++e++l+ia++ FUN_000334-T1 24 FQEALNKYEKQLKIATKA--GDRAGVGWAYLNLGIAYYFHSDFPKAIECYEKSLNIARE 80 89****************..99**********************************986 PP == domain 2 score: 59.4 bits; conditional E-value: 6.2e-19 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + nl++++ +g++ +A+e++ek l++a+++ +d++++ +++nLg++y +gd+ +A+e++e++l+ia++ FUN_000334-T1 91 YFNLGNAYKCQGDFPKAIECYEKRLNIAREA--GDRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSLNIARE 160 669****************************..89999*******************************986 PP == domain 3 score: 54.7 bits; conditional E-value: 1.8e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++++l+ ++ + ++ +A+e++ek+l++a+++ +d++++ +++ Lg +y + d+ +A+e++e++l+ia++ FUN_000334-T1 170 VYYGLGLAYNSQSDFPKAIECYEKSLNIARQA--GDRDGEKDVYYSLGLAYNSQSDFPKAIECYEKSLNIARE 240 5789****************************..89999*******************************986 PP == domain 4 score: 50.0 bits; conditional E-value: 5.1e-16 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++++l+ ++ + ++ +A+e++ek+l++a+++ +d+ + +a++++g +y + d +A+e++e++l+ia++ FUN_000334-T1 250 VYYGLGLAYNSQSDFPKAIECYEKSLNIAREA--GDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIARE 320 5789****************************..8999********************************986 PP == domain 5 score: 50.7 bits; conditional E-value: 3.2e-16 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ +++ ++ + + +A+e++ek+l++a+++ d++ + +++nLg +y + d+ +A+e++e++l+ia++ FUN_000334-T1 289 RAYFGIGLAYKSQSDVLKAIECYEKSLNIAREA--RDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSLNIARE 360 577789***************************..5666699*****************************986 PP == domain 6 score: 49.9 bits; conditional E-value: 5.6e-16 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + nl++++ + ++ +A+e++ek+l++a+++ +d+ + +a++++g +y + d +A+e++e++l+ia++ FUN_000334-T1 331 YFNLGNAYKSQSDFPKAIECYEKSLNIAREA--GDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIARE 400 669****************************..8999********************************986 PP == domain 7 score: 50.7 bits; conditional E-value: 3.2e-16 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ +++ ++ + + +A+e++ek+l++a+++ d++ + +++nLg +y + d+ +A+e++e++l+ia++ FUN_000334-T1 369 RAYFGIGLAYKSQSDVLKAIECYEKSLNIAREA--RDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSLNIARE 440 577789***************************..5666699*****************************986 PP == domain 8 score: 56.6 bits; conditional E-value: 4.4e-18 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + nl++++ + ++ +A+e++ek+l++a+++ +d+ + +a++n+g +y + d+ +A+e++e++l+ia++ FUN_000334-T1 451 YFNLGNAYKSQSDFPKAIECYEKSLNIAREA--GDKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSLNIARE 520 669****************************..9999********************************986 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.3 2e-08 1.4e-05 2 31 .. 49 78 .. 48 80 .. 0.92 2 ! 28.7 0.3 1.6e-09 1.1e-06 2 26 .. 89 113 .. 89 115 .. 0.96 3 ! 29.6 0.1 8.1e-10 5.6e-07 2 31 .. 129 158 .. 129 160 .. 0.92 4 ! 29.6 0.1 7.9e-10 5.5e-07 2 31 .. 169 198 .. 169 200 .. 0.92 5 ! 29.1 0.1 1.1e-09 7.9e-07 2 31 .. 209 238 .. 209 240 .. 0.92 6 ! 29.6 0.1 7.9e-10 5.4e-07 2 31 .. 249 278 .. 249 280 .. 0.92 7 ! 21.6 0.1 2.8e-07 0.00019 2 31 .. 289 318 .. 288 320 .. 0.93 8 ! 32.5 0.1 9.5e-11 6.6e-08 2 31 .. 329 358 .. 329 360 .. 0.92 9 ! 21.6 0.1 2.8e-07 0.00019 2 31 .. 369 398 .. 368 400 .. 0.93 10 ! 32.5 0.1 9.5e-11 6.6e-08 2 31 .. 409 438 .. 409 440 .. 0.92 11 ! 32.5 0.1 9.5e-11 6.6e-08 2 31 .. 449 478 .. 449 480 .. 0.92 12 ! 29.9 0.1 6.4e-10 4.4e-07 2 31 .. 489 518 .. 488 520 .. 0.93 13 ? 3.2 0.0 0.17 1.2e+02 19 29 .. 558 568 .. 557 569 .. 0.89 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 2e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay+ ++ +A+e+yek L + FUN_000334-T1 49 WAYLNLGIAYYFHSDFPKAIECYEKSLNIA 78 59************************9775 PP == domain 2 score: 28.7 bits; conditional E-value: 1.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 ++++nlGnay +g++ +A+e+yek FUN_000334-T1 89 DVYFNLGNAYKCQGDFPKAIECYEK 113 58**********************8 PP == domain 3 score: 29.6 bits; conditional E-value: 8.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlG ay +g++ +A+e+yek L + FUN_000334-T1 129 DVYFNLGDAYNFQGDFPKAIECYEKSLNIA 158 58************************9775 PP == domain 4 score: 29.6 bits; conditional E-value: 7.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++y+lG+ay ++ ++ +A+e+yek L + FUN_000334-T1 169 DVYYGLGLAYNSQSDFPKAIECYEKSLNIA 198 68************************9775 PP == domain 5 score: 29.1 bits; conditional E-value: 1.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++y lG+ay ++ ++ +A+e+yek L + FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIECYEKSLNIA 238 68************************9775 PP == domain 6 score: 29.6 bits; conditional E-value: 7.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++y+lG+ay ++ ++ +A+e+yek L + FUN_000334-T1 249 DVYYGLGLAYNSQSDFPKAIECYEKSLNIA 278 68************************9775 PP == domain 7 score: 21.6 bits; conditional E-value: 2.8e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++++G+ay ++ + +A+e+yek L + FUN_000334-T1 289 RAYFGIGLAYKSQSDVLKAIECYEKSLNIA 318 79************************9775 PP == domain 8 score: 32.5 bits; conditional E-value: 9.5e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlGnay ++ ++ +A+e+yek L + FUN_000334-T1 329 DVYFNLGNAYKSQSDFPKAIECYEKSLNIA 358 58************************9775 PP == domain 9 score: 21.6 bits; conditional E-value: 2.8e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++++G+ay ++ + +A+e+yek L + FUN_000334-T1 369 RAYFGIGLAYKSQSDVLKAIECYEKSLNIA 398 79************************9775 PP == domain 10 score: 32.5 bits; conditional E-value: 9.5e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlGnay ++ ++ +A+e+yek L + FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIECYEKSLNIA 438 58************************9775 PP == domain 11 score: 32.5 bits; conditional E-value: 9.5e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlGnay ++ ++ +A+e+yek L + FUN_000334-T1 449 DVYFNLGNAYKSQSDFPKAIECYEKSLNIA 478 58************************9775 PP == domain 12 score: 29.9 bits; conditional E-value: 6.4e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++n+G ay ++ ++ +A+e+yek L + FUN_000334-T1 489 RAYFNIGSAYKSQSDFPKAIECYEKSLNIA 518 79************************9775 PP == domain 13 score: 3.2 bits; conditional E-value: 0.17 TPR_1 19 eAleyyekALe 29 Ale+y+kAL+ FUN_000334-T1 558 RALEAYNKALT 568 59*******95 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.021 15 15 36 .] 24 45 .. 22 45 .. 0.92 2 ! 12.4 0.0 0.00028 0.19 1 35 [. 50 84 .. 50 85 .. 0.95 3 ! 24.9 0.0 2.7e-08 1.9e-05 2 35 .. 91 124 .. 90 125 .. 0.95 4 ! 19.4 0.0 1.6e-06 0.0011 2 35 .. 131 164 .. 130 165 .. 0.95 5 ! 15.7 0.0 2.5e-05 0.017 3 35 .. 172 204 .. 170 205 .. 0.94 6 ! 15.5 0.0 2.8e-05 0.02 2 35 .. 211 244 .. 210 245 .. 0.94 7 ! 14.2 0.0 7.1e-05 0.049 3 35 .. 252 284 .. 250 284 .. 0.94 8 ! 9.5 0.1 0.0023 1.6 1 35 [. 290 324 .. 290 325 .. 0.92 9 ! 20.7 0.0 6e-07 0.00042 2 35 .. 331 364 .. 330 364 .. 0.95 10 ! 9.5 0.1 0.0023 1.6 1 35 [. 370 404 .. 370 405 .. 0.92 11 ! 20.5 0.0 6.9e-07 0.00048 2 35 .. 411 444 .. 410 445 .. 0.94 12 ! 20.5 0.0 7e-07 0.00048 2 35 .. 451 484 .. 450 485 .. 0.94 13 ! 18.5 0.0 3.1e-06 0.0021 1 34 [. 490 523 .. 490 525 .. 0.94 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.021 TPR_7 15 ydeAirlyerlLalakdpedre 36 ++eA++ ye++L +a + +dr+ FUN_000334-T1 24 FQEALNKYEKQLKIATKAGDRA 45 79**************999985 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00028 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y d+ +Ai++ye+ L +a++ +dr FUN_000334-T1 50 AYLNLGIAYYFHSDFPKAIECYEKSLNIAREARDR 84 789***************************99987 PP == domain 3 score: 24.9 bits; conditional E-value: 2.7e-08 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y +Gd+ +Ai++ye+ L +a++ +dr FUN_000334-T1 91 YFNLGNAYKCQGDFPKAIECYEKRLNIAREAGDR 124 579***************************9998 PP == domain 4 score: 19.4 bits; conditional E-value: 1.6e-06 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y +Gd+ +Ai++ye+ L +a++ +dr FUN_000334-T1 131 YFNLGDAYNFQGDFPKAIECYEKSLNIAREAGDR 164 579***************************9998 PP == domain 5 score: 15.7 bits; conditional E-value: 2.5e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 + L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000334-T1 172 YGLGLAYNSQSDFPKAIECYEKSLNIARQAGDR 204 689***************************998 PP == domain 6 score: 15.5 bits; conditional E-value: 2.8e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000334-T1 211 YYSLGLAYNSQSDFPKAIECYEKSLNIAREAGDR 244 579***************************9998 PP == domain 7 score: 14.2 bits; conditional E-value: 7.1e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 + L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000334-T1 252 YGLGLAYNSQSDFPKAIECYEKSLNIAREAGDR 284 689*************************99997 PP == domain 8 score: 9.5 bits; conditional E-value: 0.0023 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ ++ +y ++ d +Ai++ye+ L +a++ +dr FUN_000334-T1 290 AYFGIGLAYKSQSDVLKAIECYEKSLNIAREARDR 324 567899************************99987 PP == domain 9 score: 20.7 bits; conditional E-value: 6e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y ++ d+ +Ai++ye+ L +a++ +dr FUN_000334-T1 331 YFNLGNAYKSQSDFPKAIECYEKSLNIAREAGDR 364 579**************************99997 PP == domain 10 score: 9.5 bits; conditional E-value: 0.0023 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ ++ +y ++ d +Ai++ye+ L +a++ +dr FUN_000334-T1 370 AYFGIGLAYKSQSDVLKAIECYEKSLNIAREARDR 404 567899************************99987 PP == domain 11 score: 20.5 bits; conditional E-value: 6.9e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y ++ d+ +Ai++ye+ L +a++ +dr FUN_000334-T1 411 YFNLGNAYKSQSDFPKAIECYEKSLNIAREARDR 444 579**************************99987 PP == domain 12 score: 20.5 bits; conditional E-value: 7e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y ++ d+ +Ai++ye+ L +a++ +d+ FUN_000334-T1 451 YFNLGNAYKSQSDFPKAIECYEKSLNIAREAGDK 484 579**************************99986 PP == domain 13 score: 18.5 bits; conditional E-value: 3.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+ +++++y ++ d+ +Ai++ye+ L +a++ +d FUN_000334-T1 490 AYFNIGSAYKSQSDFPKAIECYEKSLNIAREAGD 523 789***************************9988 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 8.8 6.1e+03 17 26 .. 24 33 .. 24 39 .. 0.81 2 ! 20.0 0.3 1e-06 0.00072 3 32 .. 50 79 .. 48 81 .. 0.93 3 ! 24.3 0.1 4.2e-08 2.9e-05 2 26 .. 89 113 .. 88 120 .. 0.93 4 ! 21.6 0.1 3.2e-07 0.00022 2 32 .. 129 159 .. 128 161 .. 0.93 5 ! 16.5 0.1 1.3e-05 0.0092 2 32 .. 169 199 .. 168 201 .. 0.92 6 ! 15.9 0.1 2.2e-05 0.015 3 32 .. 210 239 .. 208 241 .. 0.92 7 ! 16.5 0.1 1.3e-05 0.0092 2 32 .. 249 279 .. 248 281 .. 0.92 8 ! 16.1 0.1 1.8e-05 0.013 2 32 .. 289 319 .. 288 321 .. 0.93 9 ! 24.8 0.1 3.1e-08 2.1e-05 2 32 .. 329 359 .. 328 361 .. 0.93 10 ! 16.1 0.1 1.8e-05 0.013 2 32 .. 369 399 .. 368 401 .. 0.93 11 ! 24.8 0.1 3.1e-08 2.1e-05 2 32 .. 409 439 .. 408 441 .. 0.93 12 ! 24.8 0.1 3.1e-08 2.1e-05 2 32 .. 449 479 .. 448 481 .. 0.93 13 ! 21.3 0.0 3.9e-07 0.00027 2 32 .. 489 519 .. 488 521 .. 0.93 14 ? 1.1 0.0 1.2 8e+02 19 28 .. 558 567 .. 557 571 .. 0.89 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 8.8 TPR_2 17 yeeAleayek 26 ++eAl+ yek FUN_000334-T1 24 FQEALNKYEK 33 7899999998 PP == domain 2 score: 20.0 bits; conditional E-value: 1e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a+ nlG ayy d+ +A+e+yek+l ++ FUN_000334-T1 50 AYLNLGIAYYFHSDFPKAIECYEKSLNIAR 79 899***********************9875 PP == domain 3 score: 24.3 bits; conditional E-value: 4.2e-08 TPR_2 2 ealynlGlayyklgdyeeAleayek 26 ++++nlG+ay +gd+ +A+e+yek FUN_000334-T1 89 DVYFNLGNAYKCQGDFPKAIECYEK 113 58**********************8 PP == domain 4 score: 21.6 bits; conditional E-value: 3.2e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG+ay +gd+ +A+e+yek+l ++ FUN_000334-T1 129 DVYFNLGDAYNFQGDFPKAIECYEKSLNIAR 159 58*************************9875 PP == domain 5 score: 16.5 bits; conditional E-value: 1.3e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +++y lGlay + d+ +A+e+yek+l ++ FUN_000334-T1 169 DVYYGLGLAYNSQSDFPKAIECYEKSLNIAR 199 589************************9875 PP == domain 6 score: 15.9 bits; conditional E-value: 2.2e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 ++y lGlay + d+ +A+e+yek+l ++ FUN_000334-T1 210 VYYSLGLAYNSQSDFPKAIECYEKSLNIAR 239 89************************9875 PP == domain 7 score: 16.5 bits; conditional E-value: 1.3e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +++y lGlay + d+ +A+e+yek+l ++ FUN_000334-T1 249 DVYYGLGLAYNSQSDFPKAIECYEKSLNIAR 279 589************************9875 PP == domain 8 score: 16.1 bits; conditional E-value: 1.8e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++ Glay + d +A+e+yek+l ++ FUN_000334-T1 289 RAYFGIGLAYKSQSDVLKAIECYEKSLNIAR 319 69*************************9875 PP == domain 9 score: 24.8 bits; conditional E-value: 3.1e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG+ay + d+ +A+e+yek+l ++ FUN_000334-T1 329 DVYFNLGNAYKSQSDFPKAIECYEKSLNIAR 359 58*************************9875 PP == domain 10 score: 16.1 bits; conditional E-value: 1.8e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++ Glay + d +A+e+yek+l ++ FUN_000334-T1 369 RAYFGIGLAYKSQSDVLKAIECYEKSLNIAR 399 69*************************9875 PP == domain 11 score: 24.8 bits; conditional E-value: 3.1e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG+ay + d+ +A+e+yek+l ++ FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIECYEKSLNIAR 439 58*************************9875 PP == domain 12 score: 24.8 bits; conditional E-value: 3.1e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG+ay + d+ +A+e+yek+l ++ FUN_000334-T1 449 DVYFNLGNAYKSQSDFPKAIECYEKSLNIAR 479 58*************************9875 PP == domain 13 score: 21.3 bits; conditional E-value: 3.9e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++n G ay + d+ +A+e+yek+l ++ FUN_000334-T1 489 RAYFNIGSAYKSQSDFPKAIECYEKSLNIAR 519 69*************************9875 PP == domain 14 score: 1.1 bits; conditional E-value: 1.2 TPR_2 19 eAleayekAl 28 +Aleay+kAl FUN_000334-T1 558 RALEAYNKAL 567 69*******9 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.2 0.0011 0.78 3 32 .. 50 79 .. 50 80 .. 0.95 2 ! 16.1 0.1 1.9e-05 0.013 3 31 .. 90 118 .. 89 120 .. 0.89 3 ! 23.9 0.0 5.7e-08 3.9e-05 2 32 .. 129 159 .. 128 160 .. 0.94 4 ! 17.4 0.1 7.4e-06 0.0051 3 32 .. 170 199 .. 169 200 .. 0.94 5 ! 17.9 0.1 4.9e-06 0.0034 3 32 .. 210 239 .. 209 240 .. 0.94 6 ! 17.2 0.1 8.7e-06 0.006 3 32 .. 250 279 .. 249 280 .. 0.94 7 ! 19.0 0.2 2.2e-06 0.0015 2 32 .. 289 319 .. 288 320 .. 0.95 8 ! 21.5 0.1 3.4e-07 0.00023 3 32 .. 330 359 .. 329 360 .. 0.94 9 ! 19.0 0.2 2.2e-06 0.0015 2 32 .. 369 399 .. 368 400 .. 0.95 10 ! 21.5 0.1 3.4e-07 0.00023 3 32 .. 410 439 .. 409 440 .. 0.94 11 ! 21.5 0.1 3.4e-07 0.00023 3 32 .. 450 479 .. 449 480 .. 0.94 12 ! 23.1 0.1 1.1e-07 7.6e-05 2 32 .. 489 519 .. 488 520 .. 0.95 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0011 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay+nlG +y d+ +A+e+yek+l +++ FUN_000334-T1 50 AYLNLGIAYYFHSDFPKAIECYEKSLNIAR 79 79************************9987 PP == domain 2 score: 16.1 bits; conditional E-value: 1.9e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 +y+nlG++y+ +gd+ +A+e+yek l ++ FUN_000334-T1 90 VYFNLGNAYKCQGDFPKAIECYEKRLNIA 118 8**********************977666 PP == domain 3 score: 23.9 bits; conditional E-value: 5.7e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++y+nlG++y +gd+ +A+e+yek+l +++ FUN_000334-T1 129 DVYFNLGDAYNFQGDFPKAIECYEKSLNIAR 159 58*************************9987 PP == domain 4 score: 17.4 bits; conditional E-value: 7.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +yy lGl+y ++ d+ +A+e+yek+l +++ FUN_000334-T1 170 VYYGLGLAYNSQSDFPKAIECYEKSLNIAR 199 8*************************9987 PP == domain 5 score: 17.9 bits; conditional E-value: 4.9e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +yy lGl+y ++ d+ +A+e+yek+l +++ FUN_000334-T1 210 VYYSLGLAYNSQSDFPKAIECYEKSLNIAR 239 8*************************9987 PP == domain 6 score: 17.2 bits; conditional E-value: 8.7e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +yy lGl+y ++ d+ +A+e+yek+l +++ FUN_000334-T1 250 VYYGLGLAYNSQSDFPKAIECYEKSLNIAR 279 8*************************9987 PP == domain 7 score: 19.0 bits; conditional E-value: 2.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ +Gl+y+++ d +A+e+yek+l +++ FUN_000334-T1 289 RAYFGIGLAYKSQSDVLKAIECYEKSLNIAR 319 89*************************9987 PP == domain 8 score: 21.5 bits; conditional E-value: 3.4e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y+nlG++y+++ d+ +A+e+yek+l +++ FUN_000334-T1 330 VYFNLGNAYKSQSDFPKAIECYEKSLNIAR 359 8*************************9987 PP == domain 9 score: 19.0 bits; conditional E-value: 2.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ +Gl+y+++ d +A+e+yek+l +++ FUN_000334-T1 369 RAYFGIGLAYKSQSDVLKAIECYEKSLNIAR 399 89*************************9987 PP == domain 10 score: 21.5 bits; conditional E-value: 3.4e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y+nlG++y+++ d+ +A+e+yek+l +++ FUN_000334-T1 410 VYFNLGNAYKSQSDFPKAIECYEKSLNIAR 439 8*************************9987 PP == domain 11 score: 21.5 bits; conditional E-value: 3.4e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y+nlG++y+++ d+ +A+e+yek+l +++ FUN_000334-T1 450 VYFNLGNAYKSQSDFPKAIECYEKSLNIAR 479 8*************************9987 PP == domain 12 score: 23.1 bits; conditional E-value: 1.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+n+G++y+++ d+ +A+e+yek+l +++ FUN_000334-T1 489 RAYFNIGSAYKSQSDFPKAIECYEKSLNIAR 519 89*************************9987 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.6 0.0 0.00022 0.15 3 35 .. 49 81 .. 47 86 .. 0.91 2 ! 10.4 0.0 0.001 0.72 7 34 .. 93 120 .. 91 121 .. 0.92 3 ! 11.5 0.0 0.0005 0.34 7 35 .. 133 161 .. 131 161 .. 0.96 4 ! 8.9 0.0 0.003 2.1 7 34 .. 173 200 .. 169 201 .. 0.91 5 ! 10.2 0.0 0.0012 0.82 5 35 .. 211 241 .. 209 241 .. 0.92 6 ! 9.3 0.0 0.0024 1.7 7 35 .. 253 281 .. 249 281 .. 0.92 7 ? 2.5 0.0 0.33 2.3e+02 8 35 .. 294 321 .. 293 326 .. 0.88 8 ! 13.1 0.0 0.00015 0.1 7 35 .. 333 361 .. 331 361 .. 0.96 9 ? 2.5 0.0 0.33 2.3e+02 8 35 .. 374 401 .. 373 406 .. 0.88 10 ! 14.0 0.0 8.1e-05 0.056 7 35 .. 413 441 .. 411 446 .. 0.93 11 ! 13.1 0.0 0.00015 0.1 7 35 .. 453 481 .. 451 481 .. 0.96 12 ! 9.9 0.0 0.0015 1 7 35 .. 493 521 .. 489 521 .. 0.94 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00022 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL+ a++ ++ A e +e++l i++++ FUN_000334-T1 49 WAYLNLGIAYYFHSDFPKAIECYEKSLNIAREA 81 699***************************997 PP == domain 2 score: 10.4 bits; conditional E-value: 0.001 TPR_10 7 nLanalraqgryeeAeelleealairer 34 nL+na+ qg++ A e +e+ l i+++ FUN_000334-T1 93 NLGNAYKCQGDFPKAIECYEKRLNIARE 120 9*******************98888876 PP == domain 3 score: 11.5 bits; conditional E-value: 0.0005 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ qg++ A e +e++l i++++ FUN_000334-T1 133 NLGDAYNFQGDFPKAIECYEKSLNIAREA 161 9************************9985 PP == domain 4 score: 8.9 bits; conditional E-value: 0.003 TPR_10 7 nLanalraqgryeeAeelleealairer 34 L+ a+ +q ++ A e +e++l i+++ FUN_000334-T1 173 GLGLAYNSQSDFPKAIECYEKSLNIARQ 200 69***********************998 PP == domain 5 score: 10.2 bits; conditional E-value: 0.0012 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + L+ a+ +q ++ A e +e++l i++++ FUN_000334-T1 211 YYSLGLAYNSQSDFPKAIECYEKSLNIAREA 241 668************************9985 PP == domain 6 score: 9.3 bits; conditional E-value: 0.0024 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 L+ a+ +q ++ A e +e++l i++++ FUN_000334-T1 253 GLGLAYNSQSDFPKAIECYEKSLNIAREA 281 69***********************9985 PP == domain 7 score: 2.5 bits; conditional E-value: 0.33 TPR_10 8 LanalraqgryeeAeelleealairerv 35 ++ a+ +q + A e +e++l i++++ FUN_000334-T1 294 IGLAYKSQSDVLKAIECYEKSLNIAREA 321 6889999999999***********9997 PP == domain 8 score: 13.1 bits; conditional E-value: 0.00015 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+na+ +q ++ A e +e++l i++++ FUN_000334-T1 333 NLGNAYKSQSDFPKAIECYEKSLNIAREA 361 9************************9985 PP == domain 9 score: 2.5 bits; conditional E-value: 0.33 TPR_10 8 LanalraqgryeeAeelleealairerv 35 ++ a+ +q + A e +e++l i++++ FUN_000334-T1 374 IGLAYKSQSDVLKAIECYEKSLNIAREA 401 6889999999999***********9997 PP == domain 10 score: 14.0 bits; conditional E-value: 8.1e-05 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+na+ +q ++ A e +e++l i++++ FUN_000334-T1 413 NLGNAYKSQSDFPKAIECYEKSLNIAREA 441 9*************************997 PP == domain 11 score: 13.1 bits; conditional E-value: 0.00015 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+na+ +q ++ A e +e++l i++++ FUN_000334-T1 453 NLGNAYKSQSDFPKAIECYEKSLNIAREA 481 9************************9985 PP == domain 12 score: 9.9 bits; conditional E-value: 0.0015 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 n++ a+ +q ++ A e +e++l i++++ FUN_000334-T1 493 NIGSAYKSQSDFPKAIECYEKSLNIAREA 521 9************************9985 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.035 24 2 25 .. 50 73 .. 49 77 .. 0.91 2 ? 6.5 0.0 0.031 22 1 25 [. 89 113 .. 89 113 .. 0.94 3 ! 11.6 0.0 0.00075 0.52 1 25 [. 129 153 .. 129 157 .. 0.93 4 ! 8.1 0.0 0.0095 6.6 1 25 [. 169 193 .. 169 197 .. 0.93 5 ? 6.6 0.0 0.029 20 1 25 [. 209 233 .. 209 237 .. 0.92 6 ! 8.1 0.0 0.0095 6.6 1 25 [. 249 273 .. 249 277 .. 0.93 7 ? 6.2 0.0 0.039 27 2 25 .. 290 313 .. 289 317 .. 0.93 8 ! 8.1 0.0 0.0094 6.5 1 25 [. 329 353 .. 329 357 .. 0.93 9 ? 6.2 0.0 0.039 27 2 25 .. 370 393 .. 369 397 .. 0.93 10 ! 8.1 0.0 0.0094 6.5 1 25 [. 409 433 .. 409 437 .. 0.93 11 ! 8.1 0.0 0.0094 6.5 1 25 [. 449 473 .. 449 477 .. 0.93 12 ? 8.0 0.0 0.01 7.2 2 25 .. 490 513 .. 489 517 .. 0.93 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.035 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+l+l+ +y+ d+ +A++ +++ FUN_000334-T1 50 AYLNLGIAYYFHSDFPKAIECYEK 73 99*********77*********98 PP == domain 2 score: 6.5 bits; conditional E-value: 0.031 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+ +y+ +gd+ +A++ +++ FUN_000334-T1 89 DVYFNLGNAYKCQGDFPKAIECYEK 113 789********999*********96 PP == domain 3 score: 11.6 bits; conditional E-value: 0.00075 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+++y +gd+ +A++ +++ FUN_000334-T1 129 DVYFNLGDAYNFQGDFPKAIECYEK 153 789********************98 PP == domain 4 score: 8.1 bits; conditional E-value: 0.0095 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d+++ l+l+y + d+ +A++ +++ FUN_000334-T1 169 DVYYGLGLAYNSQSDFPKAIECYEK 193 789********************98 PP == domain 5 score: 6.6 bits; conditional E-value: 0.029 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d+++ l+l+y + d+ +A++ +++ FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIECYEK 233 789********************98 PP == domain 6 score: 8.1 bits; conditional E-value: 0.0095 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d+++ l+l+y + d+ +A++ +++ FUN_000334-T1 249 DVYYGLGLAYNSQSDFPKAIECYEK 273 789********************98 PP == domain 7 score: 6.2 bits; conditional E-value: 0.039 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A++ ++l+y+ + d +A++ +++ FUN_000334-T1 290 AYFGIGLAYKSQSDVLKAIECYEK 313 99********************98 PP == domain 8 score: 8.1 bits; conditional E-value: 0.0094 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+ +y+ + d+ +A++ +++ FUN_000334-T1 329 DVYFNLGNAYKSQSDFPKAIECYEK 353 789********************98 PP == domain 9 score: 6.2 bits; conditional E-value: 0.039 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A++ ++l+y+ + d +A++ +++ FUN_000334-T1 370 AYFGIGLAYKSQSDVLKAIECYEK 393 99********************98 PP == domain 10 score: 8.1 bits; conditional E-value: 0.0094 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+ +y+ + d+ +A++ +++ FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIECYEK 433 789********************98 PP == domain 11 score: 8.1 bits; conditional E-value: 0.0094 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+ +y+ + d+ +A++ +++ FUN_000334-T1 449 DVYFNLGNAYKSQSDFPKAIECYEK 473 789********************98 PP == domain 12 score: 8.0 bits; conditional E-value: 0.01 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++++ +y+ + d+ +A++ +++ FUN_000334-T1 490 AYFNIGSAYKSQSDFPKAIECYEK 513 9*********************98 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 5.1 3.5e+03 10 19 .. 24 33 .. 22 37 .. 0.78 2 ? 2.2 1.4 0.31 2.1e+02 29 39 .. 49 59 .. 49 61 .. 0.94 3 ! 8.9 0.5 0.0024 1.6 9 42 .] 63 102 .. 61 102 .. 0.73 4 ! 11.5 0.0 0.00037 0.26 1 19 [. 95 113 .. 95 120 .. 0.92 5 ! 14.2 0.0 5.5e-05 0.038 1 23 [. 135 157 .. 135 161 .. 0.94 6 ! 11.7 0.0 0.00032 0.22 1 23 [. 175 197 .. 175 201 .. 0.93 7 ! 11.6 0.0 0.00034 0.23 1 23 [. 215 237 .. 215 241 .. 0.93 8 ! 11.6 0.0 0.00034 0.23 1 23 [. 255 277 .. 255 281 .. 0.93 9 ? 6.0 0.2 0.02 14 1 23 [. 295 317 .. 289 321 .. 0.92 10 ! 14.2 0.1 5.2e-05 0.036 1 23 [. 335 357 .. 329 361 .. 0.95 11 ? 6.0 0.2 0.02 14 1 23 [. 375 397 .. 369 401 .. 0.92 12 ! 14.2 0.1 5.2e-05 0.036 1 23 [. 415 437 .. 409 441 .. 0.95 13 ! 14.2 0.0 5.5e-05 0.038 1 23 [. 455 477 .. 449 480 .. 0.96 14 ! 11.4 0.0 0.00041 0.28 1 23 [. 495 517 .. 495 520 .. 0.94 15 ? 0.9 0.1 0.79 5.4e+02 13 21 .. 559 567 .. 557 568 .. 0.89 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 5.1 TPR_11 10 yeeAieaYkk 19 + eA+++Y+k FUN_000334-T1 24 FQEALNKYEK 33 689*****98 PP == domain 2 score: 2.2 bits; conditional E-value: 0.31 TPR_11 29 eayynLGlayy 39 +ay+nLG ayy FUN_000334-T1 49 WAYLNLGIAYY 59 69********9 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0024 TPR_11 9 kyeeAieaYkkAlkl......dPdnaeayynLGlayykqG 42 ++++Aie+Y+k l++ + + ++y+nLG+ay qG FUN_000334-T1 63 DFPKAIECYEKSLNIareardRDSEKDVYFNLGNAYKCQG 102 578999999999999444442223358*********8776 PP == domain 4 score: 11.5 bits; conditional E-value: 0.00037 TPR_11 1 GdayyeqGkyeeAieaYkk 19 G+ay qG++++Aie+Y+k FUN_000334-T1 95 GNAYKCQGDFPKAIECYEK 113 9****************98 PP == domain 5 score: 14.2 bits; conditional E-value: 5.5e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 Gday qG++++Aie+Y+k l++ FUN_000334-T1 135 GDAYNFQGDFPKAIECYEKSLNI 157 9******************9987 PP == domain 6 score: 11.7 bits; conditional E-value: 0.00032 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q ++++Aie+Y+k l++ FUN_000334-T1 175 GLAYNSQSDFPKAIECYEKSLNI 197 89*****************9997 PP == domain 7 score: 11.6 bits; conditional E-value: 0.00034 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q ++++Aie+Y+k l++ FUN_000334-T1 215 GLAYNSQSDFPKAIECYEKSLNI 237 89*****************9987 PP == domain 8 score: 11.6 bits; conditional E-value: 0.00034 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q ++++Aie+Y+k l++ FUN_000334-T1 255 GLAYNSQSDFPKAIECYEKSLNI 277 89*****************9987 PP == domain 9 score: 6.0 bits; conditional E-value: 0.02 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q + +Aie+Y+k l++ FUN_000334-T1 295 GLAYKSQSDVLKAIECYEKSLNI 317 88999999999********9987 PP == domain 10 score: 14.2 bits; conditional E-value: 5.2e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G+ay +q ++++Aie+Y+k l++ FUN_000334-T1 335 GNAYKSQSDFPKAIECYEKSLNI 357 9******************9987 PP == domain 11 score: 6.0 bits; conditional E-value: 0.02 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q + +Aie+Y+k l++ FUN_000334-T1 375 GLAYKSQSDVLKAIECYEKSLNI 397 88999999999********9987 PP == domain 12 score: 14.2 bits; conditional E-value: 5.2e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G+ay +q ++++Aie+Y+k l++ FUN_000334-T1 415 GNAYKSQSDFPKAIECYEKSLNI 437 9******************9987 PP == domain 13 score: 14.2 bits; conditional E-value: 5.5e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G+ay +q ++++Aie+Y+k l++ FUN_000334-T1 455 GNAYKSQSDFPKAIECYEKSLNI 477 9******************9987 PP == domain 14 score: 11.4 bits; conditional E-value: 0.00041 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q ++++Aie+Y+k l++ FUN_000334-T1 495 GSAYKSQSDFPKAIECYEKSLNI 517 89*****************9987 PP == domain 15 score: 0.9 bits; conditional E-value: 0.79 TPR_11 13 AieaYkkAl 21 A+eaY+kAl FUN_000334-T1 559 ALEAYNKAL 567 9*******8 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.5 1.2 2.5e-10 1.7e-07 44 180 .. 57 193 .. 50 204 .. 0.87 2 ! 18.7 0.3 1.9e-06 0.0013 42 142 .. 175 275 .. 167 282 .. 0.85 3 ! 23.8 0.6 5.6e-08 3.9e-05 36 143 .. 209 316 .. 206 331 .. 0.92 4 ! 30.7 1.2 4.3e-10 3e-07 44 142 .. 297 395 .. 290 406 .. 0.95 5 ! 32.9 1.2 9.1e-11 6.3e-08 35 140 .. 328 433 .. 314 434 .. 0.86 6 ! 39.4 2.2 9.3e-13 6.4e-10 35 142 .. 408 515 .. 399 524 .. 0.94 Alignments for each domain: == domain 1 score: 31.5 bits; conditional E-value: 2.5e-10 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 ay + ++ +A e+++k ++ +++ ++d+ + y++ ++yk + d +A+e++ek +i e+g ++ + ++++++ y+ + +d+ kAie+Y FUN_000334-T1 57 AYYFHSDFPKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKCQgDFPKAIECYEKRLNIAREAGDRDNEKDVYFNLGDAYNFQ-GDFPKAIECY 151 6777788899999999999999999999999999999999999776888999999999999999999999999999999999999.9999999999 PP SNAP 139 eqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e++ ++ ++ + + ++ + + ++ +++kAie yek FUN_000334-T1 152 EKSLNIAREAGDRDGEKDVYYGLGLAYNSQSDFPKAIECYEK 193 999999999999999999999999889999999999999997 PP == domain 2 score: 18.7 bits; conditional E-value: 1.9e-06 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 + ay + ++ +A e+++k ++ ++++++d + y +y+++ d +A+e++ek+ +i e+g + + + ++ y+++ +d+ kAie FUN_000334-T1 175 GLAYNSQSDFPKAIECYEKSLNIARQAGDRDGEKDVYYSLGLAYNSQsDFPKAIECYEKSLNIAREAGDRDGEKDVYYGLGLAYNSQ-SDFPKAIE 269 567888999999999999999999999999999999999999998774777999999999999999999999999999999999999.99999999 PP SNAP 137 aYeqAa 142 +Ye++ FUN_000334-T1 270 CYEKSL 275 999875 PP == domain 3 score: 23.8 bits; conditional E-value: 5.6e-08 SNAP 36 dlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqd 130 d+y + + ay + ++ +A e+++k ++ ++++++d + y +y+++ d +A+e++ek+ +i e+g ++ ++ ++ i+ y+++ +d FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIECYEKSLNIAREAGDRDGEKDVYYGLGLAYNSQsDFPKAIECYEKSLNIAREAGDRNMEGRAYFGIGLAYKSQ-SD 303 677777889999*********************************999999875788************************************.** PP SNAP 131 lekAieaYeqAad 143 + kAie+Ye++ + FUN_000334-T1 304 VLKAIECYEKSLN 316 *********9865 PP == domain 4 score: 30.7 bits; conditional E-value: 4.3e-10 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 ayk + ++ +A e+++k ++ +++ ++d+ + y++ ++yk++ d +A+e++ek+ +i e+g ++ ++ ++ i+ y+++ +d+ kAie+Y FUN_000334-T1 297 AYKSQSDVLKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQsDFPKAIECYEKSLNIAREAGDRNMEGRAYFGIGLAYKSQ-SDVLKAIECY 391 8******************************************985778************************************.********** PP SNAP 139 eqAa 142 e++ FUN_000334-T1 392 EKSL 395 *976 PP == domain 5 score: 32.9 bits; conditional E-value: 9.1e-11 SNAP 35 adlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelq 129 d+y + +nayk + ++ +A e+++k ++ +++++++ ++ay+ +yk++ d +A+e++ek+ +i e+ + + ++++++ y+++ + FUN_000334-T1 328 KDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREAGDRNMEGRAYFGIGLAYKSQsDVLKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQ-S 422 5888888999999999999999999999999999999999999999999999884666999999999999888888888889999999999999.9 PP SNAP 130 dlekAieaYeq 140 d+ kAie+Ye+ FUN_000334-T1 423 DFPKAIECYEK 433 99999999997 PP == domain 6 score: 39.4 bits; conditional E-value: 9.3e-13 SNAP 35 adlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelq 129 d+y + +nayk + ++ +A e+++k ++ +++ ++d+ + y++ ++yk++ d +A+e++ek+ +i e+g ++ +++i+ y+++ + FUN_000334-T1 408 KDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQsDFPKAIECYEKSLNIAREAGDKVSEGRAYFNIGSAYKSQ-S 502 5899999*********************************************985778************************************.* PP SNAP 130 dlekAieaYeqAa 142 d+ kAie+Ye++ FUN_000334-T1 503 DFPKAIECYEKSL 515 **********976 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.003 2.1 1 55 [. 52 112 .. 52 115 .. 0.80 2 ! 12.7 0.0 0.00027 0.19 2 58 .. 93 155 .. 92 162 .. 0.84 3 ! 15.5 0.0 3.7e-05 0.025 2 58 .. 133 195 .. 132 205 .. 0.83 4 ! 11.2 0.0 0.00079 0.54 1 58 [. 172 235 .. 172 245 .. 0.82 5 ! 12.5 0.0 0.00032 0.22 2 58 .. 213 275 .. 212 285 .. 0.80 6 ? 6.7 0.1 0.02 14 1 58 [. 252 315 .. 252 325 .. 0.70 7 ! 8.2 0.0 0.0071 4.9 13 58 .. 311 355 .. 292 365 .. 0.81 8 ! 8.8 0.0 0.0045 3.1 2 58 .. 333 395 .. 332 402 .. 0.83 9 ? 7.7 0.0 0.01 7 14 58 .. 392 435 .. 391 446 .. 0.81 10 ! 11.8 0.0 0.00054 0.37 2 58 .. 413 475 .. 412 483 .. 0.81 11 ! 11.8 0.0 0.00053 0.37 2 58 .. 453 515 .. 452 525 .. 0.84 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.003 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayr 55 l l+ a++ + d++ A++++e l + + +++lG a+ qg++++A++ y+ FUN_000334-T1 52 LNLGIAYYFHSDFPKAIECYEKSLNIAreardrDSEKDVYFNLGNAYKCQGDFPKAIECYE 112 5789999999999999999986542222345787899*******************98765 PP == domain 2 score: 12.7 bits; conditional E-value: 0.00027 TPR_16 2 alaraalaagdyddAaaal.eaalrrn.....PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A++++ +++ ++ + +++lG+a+ qg++++A++ y++ l FUN_000334-T1 93 NLGNAYKCQGDFPKAIECYeKRLNIAReagdrDNEKDVYFNLGDAYNFQGDFPKAIECYEKSL 155 68999999*********9966665555567**9999********************9998866 PP == domain 3 score: 15.5 bits; conditional E-value: 3.7e-05 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A++++e l + ++glGla+ q ++++A++ y++ l FUN_000334-T1 133 NLGDAYNFQGDFPKAIECYEKSLNIAreagdrDGEKDVYYGLGLAYNSQSDFPKAIECYEKSL 195 68999999***********87653333467998899*********************999887 PP == domain 4 score: 11.2 bits; conditional E-value: 0.00079 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 + l++a+ + d++ A++++e l + ++ lGla+ q ++++A++ y++ l FUN_000334-T1 172 YGLGLAYNSQSDFPKAIECYEKSLNIArqagdrDGEKDVYYSLGLAYNSQSDFPKAIECYEKSL 235 6788899999999999999987653333478997799********************9998876 PP == domain 5 score: 12.5 bits; conditional E-value: 0.00032 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ + d++ A++++e l + ++glGla+ q ++++A++ y++ l FUN_000334-T1 213 SLGLAYNSQSDFPKAIECYEKSLNIAreagdrDGEKDVYYGLGLAYNSQSDFPKAIECYEKSL 275 678888889999999999987553333466997899********************9998876 PP == domain 6 score: 6.7 bits; conditional E-value: 0.02 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 + l++a+ + d++ A++++e l +A++g Gla+ q ++ +A++ y++ l FUN_000334-T1 252 YGLGLAYNSQSDFPKAIECYEKSLNIAreagdrNMEGRAYFGIGLAYKSQSDVLKAIECYEKSL 315 5677777778888888888866542222355777778888888888888888888888777655 PP == domain 7 score: 8.2 bits; conditional E-value: 0.0071 TPR_16 13 yddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraal 58 y+ +++ +++a++r+ + +++lG a+ q ++++A++ y++ l FUN_000334-T1 311 YEKSLNIAREARDRDS-EKDVYFNLGNAYKSQSDFPKAIECYEKSL 355 5566666777788886.899*******************9998876 PP == domain 8 score: 8.8 bits; conditional E-value: 0.0045 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ + d++ A++++e l +A++g Gla+ q ++ +A++ y++ l FUN_000334-T1 333 NLGNAYKSQSDFPKAIECYEKSLNIAreagdrNMEGRAYFGIGLAYKSQSDVLKAIECYEKSL 395 699****************876533334679988999******************99888765 PP == domain 9 score: 7.7 bits; conditional E-value: 0.01 TPR_16 14 ddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraal 58 + +++ +++a++r+ + +++lG a+ q ++++A++ y++ l FUN_000334-T1 392 EKSLNIAREARDRDS-EKDVYFNLGNAYKSQSDFPKAIECYEKSL 435 566677788888886.79999*************99999888866 PP == domain 10 score: 11.8 bits; conditional E-value: 0.00054 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ + d++ A++++e l + + +++lG a+ q ++++A++ y++ l FUN_000334-T1 413 NLGNAYKSQSDFPKAIECYEKSLNIAreardrDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 475 68999999999999999998654222234588789*********************9998876 PP == domain 11 score: 11.8 bits; conditional E-value: 0.00053 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ + d++ A++++e l + +A+++ G a+ q ++++A++ y++ l FUN_000334-T1 453 NLGNAYKSQSDFPKAIECYEKSLNIAreagdkVSEGRAYFNIGSAYKSQSDFPKAIECYEKSL 515 699****************87653333467**889*********************9999876 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.29 2e+02 14 34 .] 49 69 .. 47 69 .. 0.90 2 ! 10.5 0.0 0.0013 0.86 14 34 .] 89 109 .. 85 109 .. 0.93 3 ! 9.2 0.0 0.0034 2.3 13 34 .] 128 149 .. 125 149 .. 0.90 4 ? 2.4 0.0 0.48 3.3e+02 14 34 .] 169 189 .. 166 189 .. 0.92 5 ? 3.6 0.0 0.2 1.4e+02 14 34 .] 209 229 .. 206 229 .. 0.92 6 ? 2.4 0.0 0.48 3.3e+02 14 34 .] 249 269 .. 246 269 .. 0.92 7 ! 7.7 0.0 0.0097 6.7 14 34 .] 329 349 .. 325 349 .. 0.93 8 ! 7.7 0.0 0.0097 6.7 14 34 .] 409 429 .. 405 429 .. 0.93 9 ! 7.7 0.0 0.0097 6.7 14 34 .] 449 469 .. 445 469 .. 0.93 10 ? 2.5 0.0 0.45 3.1e+02 14 34 .] 489 509 .. 487 509 .. 0.92 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.29 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL++++ ++ +A++ FUN_000334-T1 49 WAYLNLGIAYYFHSDFPKAIE 69 89*********9999999985 PP == domain 2 score: 10.5 bits; conditional E-value: 0.0013 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL+++++ +G++ +A++ FUN_000334-T1 89 DVYFNLGNAYKCQGDFPKAIE 109 79****************985 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0034 TPR_17 13 adayynLArlllnnGqleeAlq 34 d+y+nL+ ++ +G++ +A++ FUN_000334-T1 128 KDVYFNLGDAYNFQGDFPKAIE 149 589****************985 PP == domain 4 score: 2.4 bits; conditional E-value: 0.48 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+yy L+ ++ + ++ +A++ FUN_000334-T1 169 DVYYGLGLAYNSQSDFPKAIE 189 79***************9985 PP == domain 5 score: 3.6 bits; conditional E-value: 0.2 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+yy L+ ++ + ++ +A++ FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIE 229 79***************9985 PP == domain 6 score: 2.4 bits; conditional E-value: 0.48 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+yy L+ ++ + ++ +A++ FUN_000334-T1 249 DVYYGLGLAYNSQSDFPKAIE 269 79***************9985 PP == domain 7 score: 7.7 bits; conditional E-value: 0.0097 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL+++++ + ++ +A++ FUN_000334-T1 329 DVYFNLGNAYKSQSDFPKAIE 349 79****************985 PP == domain 8 score: 7.7 bits; conditional E-value: 0.0097 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL+++++ + ++ +A++ FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIE 429 79****************985 PP == domain 9 score: 7.7 bits; conditional E-value: 0.0097 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL+++++ + ++ +A++ FUN_000334-T1 449 DVYFNLGNAYKSQSDFPKAIE 469 79****************985 PP == domain 10 score: 2.5 bits; conditional E-value: 0.45 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+n + +++ + ++ +A++ FUN_000334-T1 489 RAYFNIGSAYKSQSDFPKAIE 509 59****************985 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.2 1.4e+02 70 95 .. 62 88 .. 59 99 .. 0.84 2 ? 3.0 0.0 0.23 1.6e+02 68 94 .. 100 126 .. 93 134 .. 0.84 3 ? 5.0 0.0 0.055 38 67 92 .. 139 164 .. 133 172 .. 0.85 4 ? 4.8 0.0 0.063 44 67 92 .. 179 204 .. 177 213 .. 0.84 5 ? 5.7 0.0 0.034 23 67 92 .. 219 244 .. 217 252 .. 0.85 6 ? 5.1 0.0 0.051 36 67 92 .. 259 284 .. 257 289 .. 0.88 7 ? 6.7 0.0 0.017 12 68 95 .. 300 328 .. 297 337 .. 0.84 8 ? 4.8 0.0 0.062 43 68 92 .. 340 364 .. 332 369 .. 0.86 9 ? 6.7 0.1 0.017 12 68 95 .. 380 408 .. 377 419 .. 0.84 10 ? 6.7 0.0 0.017 12 68 95 .. 420 448 .. 415 459 .. 0.84 11 ? 5.0 0.0 0.055 38 68 92 .. 460 484 .. 452 490 .. 0.86 12 ? 4.3 0.0 0.09 62 68 89 .. 500 521 .. 491 536 .. 0.88 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.2 DUF7018 70 kllekaidhyekslklieeavek.kdk 95 ++ kai+ yeksl++++ea ++ ++k FUN_000334-T1 62 SDFPKAIECYEKSLNIAREARDRdSEK 88 6899***************98884444 PP == domain 2 score: 3.0 bits; conditional E-value: 0.23 DUF7018 68 vqkllekaidhyekslklieeavekkd 94 q ++ kai+ yek l++++ea ++ + FUN_000334-T1 100 CQGDFPKAIECYEKRLNIAREAGDRDN 126 799******************988743 PP == domain 3 score: 5.0 bits; conditional E-value: 0.055 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000334-T1 139 NFQGDFPKAIECYEKSLNIAREAGDR 164 789*****************999776 PP == domain 4 score: 4.8 bits; conditional E-value: 0.063 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl+++++a ++ FUN_000334-T1 179 NSQSDFPKAIECYEKSLNIARQAGDR 204 689****************9998776 PP == domain 5 score: 5.7 bits; conditional E-value: 0.034 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000334-T1 219 NSQSDFPKAIECYEKSLNIAREAGDR 244 689*****************999776 PP == domain 6 score: 5.1 bits; conditional E-value: 0.051 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000334-T1 259 NSQSDFPKAIECYEKSLNIAREAGDR 284 689*****************998655 PP == domain 7 score: 6.7 bits; conditional E-value: 0.017 DUF7018 68 vqkllekaidhyekslklieeavek.kdk 95 q ++ kai+ yeksl++++ea ++ ++k FUN_000334-T1 300 SQSDVLKAIECYEKSLNIAREARDRdSEK 328 699******************98884444 PP == domain 8 score: 4.8 bits; conditional E-value: 0.062 DUF7018 68 vqkllekaidhyekslklieeavek 92 q ++ kai+ yeksl++++ea ++ FUN_000334-T1 340 SQSDFPKAIECYEKSLNIAREAGDR 364 699****************998655 PP == domain 9 score: 6.7 bits; conditional E-value: 0.017 DUF7018 68 vqkllekaidhyekslklieeavek.kdk 95 q ++ kai+ yeksl++++ea ++ ++k FUN_000334-T1 380 SQSDVLKAIECYEKSLNIAREARDRdSEK 408 699******************98884444 PP == domain 10 score: 6.7 bits; conditional E-value: 0.017 DUF7018 68 vqkllekaidhyekslklieeavek.kdk 95 q ++ kai+ yeksl++++ea ++ ++k FUN_000334-T1 420 SQSDFPKAIECYEKSLNIAREARDRdSEK 448 699******************98884444 PP == domain 11 score: 5.0 bits; conditional E-value: 0.055 DUF7018 68 vqkllekaidhyekslklieeavek 92 q ++ kai+ yeksl++++ea +k FUN_000334-T1 460 SQSDFPKAIECYEKSLNIAREAGDK 484 699****************998665 PP == domain 12 score: 4.3 bits; conditional E-value: 0.09 DUF7018 68 vqkllekaidhyekslklieea 89 q ++ kai+ yeksl++++ea FUN_000334-T1 500 SQSDFPKAIECYEKSLNIAREA 521 699***************9997 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.12 86 94 155 .. 22 81 .. 16 87 .. 0.75 2 ! 23.4 0.0 6.3e-08 4.3e-05 14 155 .. 61 201 .. 55 206 .. 0.87 3 ! 12.7 0.0 0.00012 0.08 41 155 .. 209 321 .. 175 331 .. 0.83 4 ! 15.6 0.0 1.5e-05 0.01 10 155 .. 257 401 .. 246 411 .. 0.88 5 ! 14.0 0.0 4.6e-05 0.032 13 155 .. 300 441 .. 296 446 .. 0.82 6 ! 11.1 0.0 0.00034 0.24 13 116 .. 420 524 .. 417 538 .. 0.87 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.12 TPR_MalT 94 GqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 G +++A++ y++ l+ a++++ +a vg+++ l+ +y d+ +A ++ +++++++r++ FUN_000334-T1 22 GGFQEALNKYEKQLKIATKAGDRA--GVGWAYLNLGIAYYFHSDFPKAIECYEKSLNIAREA 81 777888888888888888887774..788888888888888888888888888888887765 PP == domain 2 score: 23.4 bits; conditional E-value: 6.3e-08 TPR_MalT 14 qgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 ++++a+e ++ L++ +e + + ++++lG a+ +qgd+ +A + +++ +ar+a++ + + +++ + qG++ +A+e y++ l FUN_000334-T1 61 HSDFPKAIECYEKSLNIAREARDRDSeKDVYFNLGNAYKCQGDFPKAIECYEKRLNIAREAGDRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSLN 156 5677788888888888887765443337799********************************999999999************************ PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 a+e++ + ++ gl+ + + d+ +A ++ +++++++rq+ FUN_000334-T1 157 IAREAGDRD--GEKDVYYGLGLAYNSQSDFPKAIECYEKSLNIARQA 201 *****9996..788999999999999999999999999999999997 PP == domain 3 score: 12.7 bits; conditional E-value: 0.00012 TPR_MalT 41 latlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwn 136 ++++lG+a+ q d+ +A + +++ +ar+a++ + +++++ + q ++ +A+e y++ l a+e++ ++ + g ++ g + + + FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIECYEKSLNIAREAGDRDGEKDVYYGLGLAYNSQSDFPKAIECYEKSLNIAREAGDRN--MEGRAYFGIGLAYKSQS 302 46799*********************************9999*******************************9997..88888999999999999 PP TPR_MalT 137 dLeeAeqhlqqgiqlgrql 155 d +A ++ +++++++r++ FUN_000334-T1 303 DVLKAIECYEKSLNIAREA 321 9999999999999998886 PP == domain 4 score: 15.6 bits; conditional E-value: 1.5e-05 TPR_MalT 10 lavsqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyq 104 + sq ++++a+e ++ L++ +e d ++ + a++ G+a+ q d+ +A + +++ +ar+a + ++ + +++ + q ++ +A+e y+ FUN_000334-T1 257 AYNSQSDFPKAIECYEKSLNIAREAgDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYE 352 5678999999999999999999886478999****************************9999999998888889999999*************** PP TPR_MalT 105 qalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 + l a+e++ ++ + g ++ g + + + d +A ++ +++++++r++ FUN_000334-T1 353 KSLNIAREAGDRN--MEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIAREA 401 ********99997..888888899988999999999999999999988876 PP == domain 5 score: 14.0 bits; conditional E-value: 4.6e-05 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 sq ++ +a+e ++ L++ +e + + ++++lG a+ q d+ +A + +++ +ar+a++ ++ a+ + + + q + +A+e y++ l FUN_000334-T1 300 SQSDVLKAIECYEKSLNIAREARDRDSeKDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREAGDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSL 395 566677777777777777766543333367889999999999999999999999999999999999999999999999999999999999999999 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 a+e++ + ++ l++ + + d+ +A ++ +++++++r++ FUN_000334-T1 396 NIAREARDRD--SEKDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREA 441 9999999997..445788889999999999999999999999999886 PP == domain 6 score: 11.1 bits; conditional E-value: 0.00034 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 sq ++++a+e ++ L++ +e + + ++++lG a+ q d+ +A + +++ +ar+a++ + a+ + + q ++ +A+e y++ l FUN_000334-T1 420 SQSDFPKAIECYEKSLNIAREARDRDSeKDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREAGDKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSL 515 67788888888888888888875444337899*********************************99999999*********************** PP TPR_MalT 108 qlaqeskle 116 a+e++ + FUN_000334-T1 516 NIAREAGDQ 524 ***998765 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.69 4.8e+02 2 29 .. 49 76 .. 48 83 .. 0.88 2 ! 9.0 0.0 0.0056 3.9 3 29 .. 90 116 .. 88 123 .. 0.87 3 ! 8.8 0.0 0.0066 4.6 3 28 .. 130 155 .. 128 163 .. 0.87 4 ? 4.2 0.0 0.19 1.3e+02 2 28 .. 169 195 .. 168 203 .. 0.88 5 ? 4.3 0.0 0.18 1.2e+02 2 28 .. 209 235 .. 208 243 .. 0.88 6 ? 4.3 0.0 0.18 1.3e+02 2 29 .. 249 276 .. 248 284 .. 0.88 7 ? 3.8 0.0 0.27 1.9e+02 3 29 .. 330 356 .. 328 364 .. 0.87 8 ? 3.8 0.0 0.26 1.8e+02 3 29 .. 410 436 .. 408 443 .. 0.86 9 ? 3.6 0.0 0.3 2.1e+02 3 28 .. 450 475 .. 448 482 .. 0.87 10 ? 1.2 0.0 1.8 1.2e+03 3 28 .. 490 515 .. 489 522 .. 0.85 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.69 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+l l+ a+ d+ +A+e++e+ l FUN_000334-T1 49 WAYLNLGIAYYFHSDFPKAIECYEKSLN 76 68999*******************9875 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0056 TPR_14 3 awlalarallalGdpdeAlellerala 29 ++ l++a+ +Gd+ +A+e++e+ l FUN_000334-T1 90 VYFNLGNAYKCQGDFPKAIECYEKRLN 116 67789******************9875 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0066 TPR_14 3 awlalarallalGdpdeAlelleral 28 ++ l++a+ +Gd+ +A+e++e+ l FUN_000334-T1 130 VYFNLGDAYNFQGDFPKAIECYEKSL 155 67789******************977 PP == domain 4 score: 4.2 bits; conditional E-value: 0.19 TPR_14 2 eawlalarallalGdpdeAlelleral 28 ++++ l+ a+ + d+ +A+e++e+ l FUN_000334-T1 169 DVYYGLGLAYNSQSDFPKAIECYEKSL 195 57899*******************977 PP == domain 5 score: 4.3 bits; conditional E-value: 0.18 TPR_14 2 eawlalarallalGdpdeAlelleral 28 ++++ l+ a+ + d+ +A+e++e+ l FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIECYEKSL 235 57899*******************977 PP == domain 6 score: 4.3 bits; conditional E-value: 0.18 TPR_14 2 eawlalarallalGdpdeAlellerala 29 ++++ l+ a+ + d+ +A+e++e+ l FUN_000334-T1 249 DVYYGLGLAYNSQSDFPKAIECYEKSLN 276 57899*******************9875 PP == domain 7 score: 3.8 bits; conditional E-value: 0.27 TPR_14 3 awlalarallalGdpdeAlellerala 29 ++ l++a+ + d+ +A+e++e+ l FUN_000334-T1 330 VYFNLGNAYKSQSDFPKAIECYEKSLN 356 67789******************9875 PP == domain 8 score: 3.8 bits; conditional E-value: 0.26 TPR_14 3 awlalarallalGdpdeAlellerala 29 ++ l++a+ + d+ +A+e++e+ l FUN_000334-T1 410 VYFNLGNAYKSQSDFPKAIECYEKSLN 436 67789******************9875 PP == domain 9 score: 3.6 bits; conditional E-value: 0.3 TPR_14 3 awlalarallalGdpdeAlelleral 28 ++ l++a+ + d+ +A+e++e+ l FUN_000334-T1 450 VYFNLGNAYKSQSDFPKAIECYEKSL 475 67789******************977 PP == domain 10 score: 1.2 bits; conditional E-value: 1.8 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+ + a+ + d+ +A+e++e+ l FUN_000334-T1 490 AYFNIGSAYKSQSDFPKAIECYEKSL 515 56677899***************977 PP >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.9 2.7 5e-19 3.4e-16 1 142 [] 971 1131 .. 971 1131 .. 0.89 Alignments for each domain: == domain 1 score: 59.9 bits; conditional E-value: 5e-19 COR-A 1 Pkswlevreelee.kkseknyisleeyreicke.nglkeeeeqdrllkfLhdlGvllyfqddeelkdlviLkpeWlteavykvlds........ 84 P +wl+++++l+ ++ ++ i++e+ ++i++e +++++++e ++l+fLhd l++f+d el++lv+L+p+Wl+++ +v++ FUN_000334-T1 971 PIKWLKYEKTLQViLAEGHKWITIEHAKRIASEvCQIHDDQEFVTVLDFLHDQRILIHFDDTVELNKLVVLDPQWLIDVFKTVITVkrydkqer 1064 89***********99999************98658**************************99**********************988888877 PP COR-A 85 .....kevlkkkGllkeedlkkiwkek.ypaeehdellrlmekfelcyelek...eeedtylvpqlL 142 l+++G+l+e+ l++ w++ ++++ ++l+ +mekf l + ++ +++ylvp++L FUN_000334-T1 1065 gfkdlWLKLEREGILEEKLLRHAWSSIvEEQHTFESLIAIMEKFSLLCSWSSadePCSKKYLVPSML 1131 774332234567**************878888889***********99998876645699****987 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 1.9e-07 0.00013 2 68 .. 579 632 .. 578 681 .. 0.72 2 ! 26.8 0.0 9.8e-09 6.8e-06 43 91 .. 781 827 .. 758 867 .. 0.79 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 1.9e-07 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqer 68 ++l+G+++ GKtsl k + +f+++e+st+g+d + + k++ iW t+ +++ FUN_000334-T1 579 MMLIGQERSGKTSLKKSLQGLQFNPNEDSTVGIDADPSYF-------------KVTTAIWKTGKKNQ 632 58********************************987654.............23445565555544 PP == domain 2 score: 26.8 bits; conditional E-value: 9.8e-09 Roc 43 kikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.srs 91 k++++e + +i +WD+aG+ ++++h+l+++++a+++lv+d sr+ FUN_000334-T1 781 KVDKME---SEDDIYSVMWDFAGESVYYETHQLFLTSRAIYLLVYDlSRD 827 233333...345677789****************************7554 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.011 7.8 139 211 .. 52 123 .. 47 130 .. 0.84 2 ? 4.8 0.0 0.039 27 136 212 .. 89 164 .. 87 172 .. 0.77 3 ? 5.1 0.0 0.033 23 138 211 .. 131 203 .. 128 211 .. 0.69 4 ? 5.3 0.0 0.027 19 149 213 .. 222 285 .. 209 289 .. 0.61 5 ! 8.3 0.0 0.0034 2.4 148 214 .. 298 366 .. 288 369 .. 0.70 6 ? 5.0 0.0 0.033 23 149 209 .. 379 441 .. 371 450 .. 0.68 7 ! 11.0 0.0 0.00051 0.35 136 213 .. 409 485 .. 403 488 .. 0.88 8 ? 2.1 0.0 0.26 1.8e+02 187 212 .. 499 524 .. 492 525 .. 0.88 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.011 ComR_TPR 139 lsalavllllkdyekleellkvlkeiidktqdf.qkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 l++ ++ + d+ k e+ +++ +i ++++d ++k +++ l y + df kA e+Y+k + a+ gd FUN_000334-T1 52 LNLGIAYYFHSDFPKAIECYEKSLNIAREARDRdSEKDVYFNLGNAYKC--QGDFPKAIECYEKRLNIAREAGD 123 5666778889999999999999999999999862578888888888877..9************9999998888 PP == domain 2 score: 4.8 bits; conditional E-value: 0.039 ComR_TPR 136 dvllsalavllllkdyekleellkvlkeiidktqdf.qkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgde 212 dv++++ ++ + d+ k e+ ++ +i +++ d ++k +++ l y + df kA e+Y+k++ a+ gd FUN_000334-T1 89 DVYFNLGNAYKCQGDFPKAIECYEKRLNIAREAGDRdNEKDVYFNLGDAYNF--QGDFPKAIECYEKSLNIAREAGDR 164 5666777777777888887777777777887776651556777777777766..99***************9998885 PP == domain 3 score: 5.1 bits; conditional E-value: 0.033 ComR_TPR 138 llsalavllllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 ++++ ++ d+ k e+ +++ +i +++ d +k +++ l y + df kA e+Y+k++ a+ gd FUN_000334-T1 131 YFNLGDAYNFQGDFPKAIECYEKSLNIAREAGDRDgEKDVYYGLGLAYNS--QSDFPKAIECYEKSLNIARQAGD 203 55555566666666666666667777776666543256666666666666..88999999999999999998888 PP == domain 4 score: 5.3 bits; conditional E-value: 0.027 ComR_TPR 149 kdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 d+ k e+ +++ +i +++ d +k +++ l y + df kA e+Y+k++ a+ gd FUN_000334-T1 222 SDFPKAIECYEKSLNIAREAGDRDgEKDVYYGLGLAYNS--QSDFPKAIECYEKSLNIAREAGDRN 285 444444444444445555544432245566666666655..8899999999999999999888876 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0034 ComR_TPR 148 lkdyekleellkv...lkeiidktqd.fqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdevL 214 +k+ +++++++++ + +i ++++d ++k +++ l y + df kA e+Y+k++ a+ gd + FUN_000334-T1 298 YKSQSDVLKAIECyekSLNIAREARDrDSEKDVYFNLGNAYKS--QSDFPKAIECYEKSLNIAREAGDRNM 366 4455555555554000455666666624578888888888887..9******************9999876 PP == domain 6 score: 5.0 bits; conditional E-value: 0.033 ComR_TPR 149 kdyekleellkv...lkeiidktqd.fqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakll 209 k+ +++++++++ + +i ++++d ++k +++ l y + df kA e+Y+k++ a+ FUN_000334-T1 379 KSQSDVLKAIECyekSLNIAREARDrDSEKDVYFNLGNAYKS--QSDFPKAIECYEKSLNIAREA 441 444444444444000455666666624578888888888877..9**************999765 PP == domain 7 score: 11.0 bits; conditional E-value: 0.00051 ComR_TPR 136 dvllsalavllllkdyekleellkvlkeiidktqdf.qkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 dv++++ ++ + d+ k e+ +++ +i ++++d ++k +++ l y + df kA e+Y+k++ a+ gd+v FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIECYEKSLNIAREARDRdSEKDVYFNLGNAYKS--QSDFPKAIECYEKSLNIAREAGDKV 485 678888888999999999999999999****999862678899999998888..9*******************99986 PP == domain 8 score: 2.1 bits; conditional E-value: 0.26 ComR_TPR 187 kvkkdfkkAkelYqkaimfakllgde 212 k + df kA e+Y+k++ a+ gd+ FUN_000334-T1 499 KSQSDFPKAIECYEKSLNIAREAGDQ 524 46899***************999985 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.31 2.1e+02 34 66 .. 53 85 .. 50 90 .. 0.88 2 ? 4.2 0.0 0.093 65 3 66 .. 96 165 .. 94 166 .. 0.80 3 ? 2.8 0.0 0.25 1.7e+02 34 65 .. 173 204 .. 141 206 .. 0.67 4 ? 5.2 0.0 0.045 31 4 66 .. 177 245 .. 174 250 .. 0.77 5 ? 4.1 0.0 0.1 69 5 65 .. 218 284 .. 214 287 .. 0.67 6 ? 5.2 0.0 0.045 31 4 66 .. 257 325 .. 254 328 .. 0.78 7 ? 7.2 0.0 0.01 7.2 1 66 [. 334 405 .. 334 410 .. 0.84 8 ? 2.9 0.0 0.23 1.6e+02 1 24 [. 414 437 .. 411 446 .. 0.73 9 ? 5.8 0.0 0.028 19 1 62 [. 454 521 .. 454 525 .. 0.76 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.31 TPR_9 34 drGllyaqlgcleaAladLeaylalapdapdae 66 + G++y+ ++ +A+++ e+ l +a +a+d++ FUN_000334-T1 53 NLGIAYYFHSDFPKAIECYEKSLNIAREARDRD 85 6899999999999********999999999987 PP == domain 2 score: 4.2 bits; conditional E-value: 0.093 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 ++y + d+++a++++e l + + ++ + +++ G +y +g++ +A+++ e+ l +a +a d++ FUN_000334-T1 96 NAYKCQGDFPKAIECYEKRLNIareagdRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSLNIAREAGDRD 165 6677788899999999999888777777777778888999999999999999999999998888888875 PP == domain 3 score: 2.8 bits; conditional E-value: 0.25 TPR_9 34 drGllyaqlgcleaAladLeaylalapdapda 65 Gl+y + ++ +A+++ e+ l +a +a d+ FUN_000334-T1 173 GLGLAYNSQSDFPKAIECYEKSLNIARQAGDR 204 56777777777777777777777777777766 PP == domain 4 score: 5.2 bits; conditional E-value: 0.045 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 +y ++ d+++a++++e l + + + + ++ Gl+y + ++ +A+++ e+ l +a +a d++ FUN_000334-T1 177 AYNSQSDFPKAIECYEKSLNIarqagdRDGEKDVYYSLGLAYNSQSDFPKAIECYEKSLNIAREAGDRD 245 566788888888888888888666555555666788889999999999999999999888888888775 PP == domain 5 score: 4.1 bits; conditional E-value: 0.1 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 y ++ d+++a++++e l + + + + ++ Gl+y + ++ +A+++ e+ l +a +a d+ FUN_000334-T1 218 YNSQSDFPKAIECYEKSLNIareagdRDGEKDVYYGLGLAYNSQSDFPKAIECYEKSLNIAREAGDR 284 5667777777777777777755555544555566777888888888888888888777777777665 PP == domain 6 score: 5.2 bits; conditional E-value: 0.045 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 +y ++ d+++a++++e l + + + + ++ Gl+y + ++ +A+++ e+ l +a +a+d++ FUN_000334-T1 257 AYNSQSDFPKAIECYEKSLNIareagdRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIAREARDRD 325 567788889999999988888555544445556777789999999999999999999999999999887 PP == domain 7 score: 7.2 bits; conditional E-value: 0.01 TPR_9 1 Lkaiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 L ++y ++ d+++a++++e l + + + + ++ Gl+y + ++ +A+++ e+ l +a +a+d++ FUN_000334-T1 334 LGNAYKSQSDFPKAIECYEKSLNIareagdRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIAREARDRD 405 56889999*************999666555555667778889999999999999999999999999999987 PP == domain 8 score: 2.9 bits; conditional E-value: 0.23 TPR_9 1 Lkaiyireedleralavverllll 24 L ++y ++ d+++a++++e l + FUN_000334-T1 414 LGNAYKSQSDFPKAIECYEKSLNI 437 457788888888888888876654 PP == domain 9 score: 5.8 bits; conditional E-value: 0.028 TPR_9 1 Lkaiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapda 62 L ++y ++ d+++a++++e l + + + + +++ G++y + ++ +A+++ e+ l +a +a FUN_000334-T1 454 LGNAYKSQSDFPKAIECYEKSLNIareagdKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSLNIAREA 521 5688999999*******999999977755445555667788888888888888888888877776665 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.18 1.2e+02 149 175 .. 62 88 .. 35 90 .. 0.80 2 ? 3.1 0.0 0.15 1e+02 147 175 .. 124 168 .. 105 170 .. 0.69 3 ? 5.7 0.1 0.024 17 133 175 .. 147 208 .. 146 210 .. 0.73 4 ? 4.1 0.1 0.072 50 147 175 .. 204 248 .. 187 250 .. 0.65 5 ? 3.6 0.1 0.1 72 133 173 .. 227 286 .. 226 290 .. 0.70 6 ? 5.3 0.4 0.031 21 135 175 .. 289 328 .. 266 330 .. 0.75 7 ? 3.1 0.0 0.15 1.1e+02 137 174 .. 331 367 .. 329 370 .. 0.84 8 ? 4.9 0.1 0.042 29 136 175 .. 370 408 .. 368 410 .. 0.89 9 ? 4.4 0.0 0.06 41 137 175 .. 411 448 .. 409 450 .. 0.85 10 ? 2.1 0.0 0.31 2.1e+02 137 173 .. 451 486 .. 449 490 .. 0.83 11 ? 4.4 0.0 0.061 42 135 172 .. 489 525 .. 488 529 .. 0.92 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.18 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkeep 175 + +a++++e++l +a+++++r++e+ FUN_000334-T1 62 SDFPKAIECYEKSLNIAREARDRDSEK 88 567899*****************9886 PP == domain 2 score: 3.1 bits; conditional E-value: 0.15 DUF7380 147 g................seewvdalkrleRAlqlaaqlgkrkeep 175 + + +a++++e++l +a+++g+r+ e+ FUN_000334-T1 124 RdnekdvyfnlgdaynfQGDFPKAIECYEKSLNIAREAGDRDGEK 168 466666666666666665678899****************99876 PP == domain 3 score: 5.7 bits; conditional E-value: 0.024 DUF7380 133 AidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrkeep 175 Ai++Y +s + +++ + +a++++e++l +a+q+g+r+ e+ FUN_000334-T1 147 AIECYEKSLNIAREAgdrdgekdvyyglglaynsQSDFPKAIECYEKSLNIARQAGDRDGEK 208 6677755554444444557777777777777776678899*****************99876 PP == domain 4 score: 4.1 bits; conditional E-value: 0.072 DUF7380 147 g................seewvdalkrleRAlqlaaqlgkrkeep 175 + + +a++++e++l +a+++g+r+ e+ FUN_000334-T1 204 RdgekdvyyslglaynsQSDFPKAIECYEKSLNIAREAGDRDGEK 248 266666666666666555778899999999999999999998776 PP == domain 5 score: 3.6 bits; conditional E-value: 0.1 DUF7380 133 AidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrke 173 Ai++Y +s + +++ + +a++++e++l +a+++g+r+ FUN_000334-T1 227 AIECYEKSLNIAREAgdrdgekdvyyglglaynsQSDFPKAIECYEKSLNIAREAGDRNM 286 666665544444444444777777777777777667788999999999999999999986 PP == domain 6 score: 5.3 bits; conditional E-value: 0.031 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 +aY + +++ ++a++++e++l +a+++++r++e+ FUN_000334-T1 289 RAYFGIGLAYKSQ-SDVLKAIECYEKSLNIAREARDRDSEK 328 3566666666665.8899******************99886 PP == domain 7 score: 3.1 bits; conditional E-value: 0.15 DUF7380 137 YlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 Y + + +++ + +a++++e++l +a+++g+r+ e FUN_000334-T1 331 YFNLGNAYKSQ-SDFPKAIECYEKSLNIAREAGDRNME 367 67777777777.8899*****************99865 PP == domain 8 score: 4.9 bits; conditional E-value: 0.042 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 aY + +++ ++a++++e++l +a+++++r++e+ FUN_000334-T1 370 AYFGIGLAYKSQ-SDVLKAIECYEKSLNIAREARDRDSEK 408 888888888888.8999*******************9886 PP == domain 9 score: 4.4 bits; conditional E-value: 0.06 DUF7380 137 YlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 Y + + +++ + +a++++e++l +a+++++r++e+ FUN_000334-T1 411 YFNLGNAYKSQ-SDFPKAIECYEKSLNIAREARDRDSEK 448 67777777777.8899*******************9886 PP == domain 10 score: 2.1 bits; conditional E-value: 0.31 DUF7380 137 YlesaeeledgseewvdalkrleRAlqlaaqlgkrke 173 Y + + +++ + +a++++e++l +a+++g++ + FUN_000334-T1 451 YFNLGNAYKSQ-SDFPKAIECYEKSLNIAREAGDKVS 486 67777777777.8899****************99866 PP == domain 11 score: 4.4 bits; conditional E-value: 0.061 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrk 172 +aY ++ + +++ + +a++++e++l +a+++g+++ FUN_000334-T1 489 RAYFNIGSAYKSQ-SDFPKAIECYEKSLNIAREAGDQG 525 6999999999999.999****************99986 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.1 0.0031 2.2 92 141 .. 63 113 .. 49 120 .. 0.73 2 ! 9.2 0.6 0.00086 0.6 163 246 .. 178 269 .. 113 281 .. 0.40 3 ! 9.4 0.3 0.00074 0.51 91 142 .. 302 354 .. 290 367 .. 0.61 4 ! 9.4 0.4 0.00071 0.49 91 142 .. 382 434 .. 357 444 .. 0.63 5 ! 7.3 0.1 0.003 2.1 87 142 .. 458 514 .. 434 521 .. 0.63 6 ? -1.1 0.1 1.1 7.8e+02 117 161 .. 615 659 .. 607 675 .. 0.81 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0031 TPR_IF140-IFT172 92 klyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyek 141 ++ +a + ++k+l++a++ +dr ++ y+n + +gd+ +ai+ yek FUN_000334-T1 63 DFPKAIECYEKSLNIAREaRDRDSEKDVYFNLGNAYKCQGDFPKAIECYEK 113 555666677777777754267777888888888888888888888888876 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00086 TPR_IF140-IFT172 163 yvkkskdkelkkWwaqyle...stgeletalk.yyeaaedylslv....rvlCyledlekaaelanetgdkaacyhlarqyenadeikeaih 246 y ++s+ ++ + + l+ ++g+ + ++ yy+ y s+ + Cy + l+ a+e + g+k y l+ y+++ ++ +ai+ FUN_000334-T1 178 YNSQSDFPKAIECYEKSLNiarQAGDRDGEKDvYYSLGLAYNSQSdfpkAIECYEKSLNIAREAGDRDGEKDVYYGLGLAYNSQSDFPKAIE 269 33333333333333333321111222222222122222222232211112445555555555555555555555555555555555555555 PP == domain 3 score: 9.4 bits; conditional E-value: 0.00074 TPR_IF140-IFT172 91 nklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 +++++a + ++k+l++a++ +dr ++ y+n + ++ d+ +ai+ yeks FUN_000334-T1 302 SDVLKAIECYEKSLNIAREaRDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKS 354 34445555555666665431456666666666666666666666666666655 PP == domain 4 score: 9.4 bits; conditional E-value: 0.00071 TPR_IF140-IFT172 91 nklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 +++++a + ++k+l++a++ +dr ++ y+n + ++ d+ +ai+ yeks FUN_000334-T1 382 SDVLKAIECYEKSLNIAREaRDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKS 434 44445555555555555431455555566666666666666666666666555 PP == domain 5 score: 7.3 bits; conditional E-value: 0.003 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 y +++ +a + ++k+l++a++ d++ ++y+n ++ d+ +ai+ yeks FUN_000334-T1 458 YKSQSDFPKAIECYEKSLNIAREAgDKVSEGRAYFNIGSAYKSQSDFPKAIECYEKS 514 444444455555556666666543367777777777777777777777777777766 PP == domain 6 score: -1.1 bits; conditional E-value: 1.1 TPR_IF140-IFT172 117 ktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaLe 161 y++ + + ++g+ ++a+++ e + +++v r++f++ ++ e FUN_000334-T1 615 PSYFKVTTAIWKTGKKNQAANKEETTAPYEHHVARVVFENLREQE 659 5799999999999**************************976533 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.35 2.4e+02 17 31 .. 64 78 .. 61 82 .. 0.86 2 ? 2.5 0.0 0.21 1.4e+02 14 32 .. 141 159 .. 129 164 .. 0.77 3 ? 2.8 0.0 0.18 1.2e+02 14 32 .. 181 199 .. 180 204 .. 0.85 4 ? 3.1 0.0 0.14 93 14 32 .. 221 239 .. 209 244 .. 0.85 5 ? 2.8 0.0 0.18 1.2e+02 14 32 .. 261 279 .. 260 283 .. 0.84 6 ? 4.5 0.0 0.052 36 2 32 .. 329 359 .. 329 363 .. 0.82 7 ? 4.4 0.0 0.054 37 2 32 .. 409 439 .. 409 443 .. 0.82 8 ? 4.4 0.0 0.054 37 2 31 .. 449 478 .. 449 482 .. 0.82 9 ? 2.8 0.0 0.18 1.2e+02 14 32 .. 501 519 .. 500 523 .. 0.84 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.35 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F+ A++ ++k+L++ FUN_000334-T1 64 FPKAIECYEKSLNIA 78 999**********95 PP == domain 2 score: 2.5 bits; conditional E-value: 0.21 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 + F+ A++ ++k+L++ + FUN_000334-T1 141 QGDFPKAIECYEKSLNIAR 159 5669************965 PP == domain 3 score: 2.8 bits; conditional E-value: 0.18 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000334-T1 181 QSDFPKAIECYEKSLNIAR 199 56799***********955 PP == domain 4 score: 3.1 bits; conditional E-value: 0.14 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000334-T1 221 QSDFPKAIECYEKSLNIAR 239 6779************965 PP == domain 5 score: 2.8 bits; conditional E-value: 0.18 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000334-T1 261 QSDFPKAIECYEKSLNIAR 279 56799***********955 PP == domain 6 score: 4.5 bits; conditional E-value: 0.052 SHNi-TPR 2 dvydlLGEiSLEnenFeqAvkDlrkaLeLre 32 dvy LG+ +++ F+ A++ ++k+L++ + FUN_000334-T1 329 DVYFNLGNAYKSQSDFPKAIECYEKSLNIAR 359 677777777778899*************965 PP == domain 7 score: 4.4 bits; conditional E-value: 0.054 SHNi-TPR 2 dvydlLGEiSLEnenFeqAvkDlrkaLeLre 32 dvy LG+ +++ F+ A++ ++k+L++ + FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIECYEKSLNIAR 439 677777777778899*************955 PP == domain 8 score: 4.4 bits; conditional E-value: 0.054 SHNi-TPR 2 dvydlLGEiSLEnenFeqAvkDlrkaLeLr 31 dvy LG+ +++ F+ A++ ++k+L++ FUN_000334-T1 449 DVYFNLGNAYKSQSDFPKAIECYEKSLNIA 478 677777777778899*************95 PP == domain 9 score: 2.8 bits; conditional E-value: 0.18 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000334-T1 501 QSDFPKAIECYEKSLNIAR 519 56799***********955 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.36 2.5e+02 59 99 .. 73 113 .. 48 118 .. 0.85 2 ? 4.8 0.0 0.04 28 59 101 .. 113 155 .. 111 160 .. 0.92 3 ? 2.0 0.0 0.29 2e+02 59 101 .. 193 235 .. 172 240 .. 0.81 4 ? 0.9 0.0 0.63 4.4e+02 47 100 .. 219 274 .. 205 278 .. 0.77 5 ? 3.9 0.0 0.078 54 59 101 .. 313 355 .. 307 359 .. 0.88 6 ? 3.9 0.0 0.075 52 59 101 .. 393 435 .. 387 440 .. 0.88 7 ? 3.7 0.0 0.088 61 60 101 .. 434 475 .. 431 481 .. 0.88 8 ? 1.2 0.0 0.53 3.7e+02 59 101 .. 473 515 .. 464 518 .. 0.90 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.36 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclek 99 ++l++a+e +++++++ + +lg++ +g++ a ec+ek FUN_000334-T1 73 KSLNIAREARDRDSEKDVYFNLGNAYKCQGDFPKAIECYEK 113 578999998888889999*********************98 PP == domain 2 score: 4.8 bits; conditional E-value: 0.04 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+e +++++++ + +lgd+ +g++ a ec+ek+ FUN_000334-T1 113 KRLNIAREAGDRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSL 155 579999999999****************************985 PP == domain 3 score: 2.0 bits; conditional E-value: 0.29 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a++ +++ +++ + +lg + +++++ a ec+ek+ FUN_000334-T1 193 KSLNIARQAGDRDGEKDVYYSLGLAYNSQSDFPKAIECYEKSL 235 6799999999999999************************985 PP == domain 4 score: 0.9 bits; conditional E-value: 0.63 TPR_COPA_B 47 dpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeecleka 100 +++ F a++ ++l++a+e +++ +++ + lg + +++++ a ec+ek+ FUN_000334-T1 219 NSQSDFPKAIECyeKSLNIAREAGDRDGEKDVYYGLGLAYNSQSDFPKAIECYEKS 274 55555555655422578999999999999999999999999999999999999997 PP == domain 5 score: 3.9 bits; conditional E-value: 0.078 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+e +++++++ + +lg++ +++++ a ec+ek+ FUN_000334-T1 313 KSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 355 568899998888888999**********************985 PP == domain 6 score: 3.9 bits; conditional E-value: 0.075 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+e +++++++ + +lg++ +++++ a ec+ek+ FUN_000334-T1 393 KSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 435 568899998888888999**********************985 PP == domain 7 score: 3.7 bits; conditional E-value: 0.088 TPR_COPA_B 60 klevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 +l++a+e +++++++ + +lg++ +++++ a ec+ek+ FUN_000334-T1 434 SLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 475 68889998888888999**********************985 PP == domain 8 score: 1.2 bits; conditional E-value: 0.53 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+e ++ ++ + + ++g + +++++ a ec+ek+ FUN_000334-T1 473 KSLNIAREAGDKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSL 515 57899999999999999***********************985 PP >> TP6A_N Type IIB DNA topoisomerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.39 2.7e+02 27 58 .. 169 200 .. 168 201 .. 0.94 2 ? 4.2 0.0 0.08 55 27 58 .. 209 240 .. 208 241 .. 0.96 3 ? 3.3 0.0 0.15 1.1e+02 27 58 .. 249 280 .. 248 281 .. 0.95 4 ? 1.8 0.0 0.46 3.2e+02 36 58 .. 298 320 .. 296 321 .. 0.94 5 ? 3.4 0.0 0.14 98 27 58 .. 329 360 .. 326 361 .. 0.94 6 ? 1.8 0.0 0.46 3.2e+02 36 58 .. 378 400 .. 376 401 .. 0.94 7 ? 3.4 0.0 0.14 98 27 58 .. 409 440 .. 406 441 .. 0.94 8 ? 3.4 0.0 0.14 98 27 58 .. 449 480 .. 446 481 .. 0.94 9 ? 0.1 0.0 1.5 1e+03 34 58 .. 496 520 .. 490 521 .. 0.89 10 ? -1.2 0.2 3.7 2.6e+03 28 50 .. 803 825 .. 802 826 .. 0.82 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.39 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+YY + sQs+ ++i+ e+ l++ R+ FUN_000334-T1 169 DVYYGLGLAYNSQSDFPKAIECYEKSLNIARQ 200 89***999********************9996 PP == domain 2 score: 4.2 bits; conditional E-value: 0.08 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+YY+ + sQs+ ++i+ e+ l++ Re FUN_000334-T1 209 DVYYSLGLAYNSQSDFPKAIECYEKSLNIARE 240 89****9***********************98 PP == domain 3 score: 3.3 bits; conditional E-value: 0.15 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+YY + sQs+ ++i+ e+ l++ Re FUN_000334-T1 249 DVYYGLGLAYNSQSDFPKAIECYEKSLNIARE 280 89***99***********************98 PP == domain 4 score: 1.8 bits; conditional E-value: 0.46 TP6A_N 36 FksQsevdrliddieallgvpRe 58 +ksQs+v ++i+ e+ l++ Re FUN_000334-T1 298 YKSQSDVLKAIECYEKSLNIARE 320 89*******************98 PP == domain 5 score: 3.4 bits; conditional E-value: 0.14 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+Y + + +ksQs+ ++i+ e+ l++ Re FUN_000334-T1 329 DVYFNLGNAYKSQSDFPKAIECYEKSLNIARE 360 88999999**********************98 PP == domain 6 score: 1.8 bits; conditional E-value: 0.46 TP6A_N 36 FksQsevdrliddieallgvpRe 58 +ksQs+v ++i+ e+ l++ Re FUN_000334-T1 378 YKSQSDVLKAIECYEKSLNIARE 400 89*******************98 PP == domain 7 score: 3.4 bits; conditional E-value: 0.14 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+Y + + +ksQs+ ++i+ e+ l++ Re FUN_000334-T1 409 DVYFNLGNAYKSQSDFPKAIECYEKSLNIARE 440 88999999**********************98 PP == domain 8 score: 3.4 bits; conditional E-value: 0.14 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+Y + + +ksQs+ ++i+ e+ l++ Re FUN_000334-T1 449 DVYFNLGNAYKSQSDFPKAIECYEKSLNIARE 480 88999999**********************98 PP == domain 9 score: 0.1 bits; conditional E-value: 1.5 TP6A_N 34 elFksQsevdrliddieallgvpRe 58 + +ksQs+ ++i+ e+ l++ Re FUN_000334-T1 496 SAYKSQSDFPKAIECYEKSLNIARE 520 579*******************998 PP == domain 10 score: -1.2 bits; conditional E-value: 3.7 TP6A_N 28 iYYrdvelFksQsevdrliddie 50 +YY +lF + + + l+ d++ FUN_000334-T1 803 VYYETHQLFLTSRAIYLLVYDLS 825 8********99888877777765 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.017 12 13 63 .. 25 75 .. 23 81 .. 0.93 2 ! 9.3 0.4 0.0017 1.2 23 136 .. 75 191 .. 72 197 .. 0.76 3 ? 6.7 0.1 0.011 7.3 16 63 .. 108 155 .. 101 231 .. 0.85 4 ? 0.2 0.1 1.1 7.3e+02 36 63 .. 208 235 .. 186 243 .. 0.76 5 ? -0.1 0.0 1.3 9e+02 21 63 .. 233 275 .. 225 283 .. 0.74 6 ? 5.8 0.3 0.021 14 14 64 .. 306 356 .. 298 389 .. 0.87 7 ? 5.5 0.2 0.026 18 14 63 .. 386 435 .. 375 441 .. 0.89 8 ? 4.9 0.1 0.04 28 22 74 .. 434 486 .. 432 509 .. 0.82 9 ? 4.8 0.1 0.042 29 16 63 .. 468 515 .. 464 523 .. 0.90 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.017 RPN7 13 ekeleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 ++ l++ e++lk a + + a+++l+ y+ + d+ +A+++ye+ + FUN_000334-T1 25 QEALNKYEKQLKIATKAGDRAGVGWAYLNLGIAYYFHSDFPKAIECYEKSL 75 5789999*****99999999****************************965 PP == domain 2 score: 9.3 bits; conditional E-value: 0.0017 RPN7 23 lkdakenlgkeeirraledlaehyakigdlenAlkayer...arekttslghkidlllnlirvgiffndwalvskylekaksliekggdwerrnrl 115 l+ a+e + + ++ + +l++ y gd+ +A+++ye+ + +++ ++ d+++nl f +d+ ++ + ek ++ ++gd++ + + FUN_000334-T1 75 LNIAREARDRDSEKDVYFNLGNAYKCQGDFPKAIECYEKrlnIAREAGDRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSLNIAREAGDRDGEKDV 170 566667777777788888899999999999999999988444445555556778888888888888888888888888888888888888888888 PP RPN7 116 kvyeGlaalairkfkeAakll 136 Gla+ ++ +f +A ++ FUN_000334-T1 171 YYGLGLAYNSQSDFPKAIECY 191 888888888888888887765 PP == domain 3 score: 6.7 bits; conditional E-value: 0.011 RPN7 16 leeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 +e e++l+ a+e + ++ + +l++ y gd+ +A+++ye+ + FUN_000334-T1 108 IECYEKRLNIAREAGDRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSL 155 566788888888888888889999999999999999999999999876 PP == domain 4 score: 0.2 bits; conditional E-value: 1.1 RPN7 36 rraledlaehyakigdlenAlkayerar 63 ++ ++ l+ y + d+ +A+++ye+ + FUN_000334-T1 208 KDVYYSLGLAYNSQSDFPKAIECYEKSL 235 567888999999999999****999865 PP == domain 5 score: -0.1 bits; conditional E-value: 1.3 RPN7 21 aelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 + l+ a+e ++ ++ l+ y + d+ +A+++ye+ + FUN_000334-T1 233 KSLNIAREAGDRDGEKDVYYGLGLAYNSQSDFPKAIECYEKSL 275 555555555555556677888999999999*********9975 PP == domain 6 score: 5.8 bits; conditional E-value: 0.021 RPN7 14 keleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerare 64 k +e e+ l+ a+e + + ++ + +l++ y + d+ +A+++ye+ ++ FUN_000334-T1 306 KAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSLN 356 66788899999999*********************************9775 PP == domain 7 score: 5.5 bits; conditional E-value: 0.026 RPN7 14 keleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 k +e e+ l+ a+e + + ++ + +l++ y + d+ +A+++ye+ + FUN_000334-T1 386 KAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 435 67788899999999*********************************965 PP == domain 8 score: 4.9 bits; conditional E-value: 0.04 RPN7 22 elkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghkid 74 l+ a+e + + ++ + +l++ y + d+ +A+++ye+ ++ + +g k++ FUN_000334-T1 434 SLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREAGDKVS 486 667777888888889999**********************9988877777765 PP == domain 9 score: 4.8 bits; conditional E-value: 0.042 RPN7 16 leeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 +e e+ l+ a+e k + ra+ +++ y + d+ +A+++ye+ + FUN_000334-T1 468 IECYEKSLNIAREAGDKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSL 515 666789999999999******************************976 PP >> CoV_NSP8 Coronavirus replicase NSP8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.36 2.5e+02 32 53 .. 65 86 .. 59 93 .. 0.87 2 ? 1.6 0.0 0.44 3e+02 26 53 .. 99 126 .. 91 134 .. 0.84 3 ? 1.9 0.0 0.37 2.6e+02 28 52 .. 141 165 .. 128 169 .. 0.86 4 ? 1.6 0.0 0.45 3.1e+02 30 52 .. 183 205 .. 175 210 .. 0.83 5 ? 1.4 0.0 0.5 3.5e+02 30 52 .. 223 245 .. 212 249 .. 0.83 6 ? 0.5 0.0 0.97 6.7e+02 30 52 .. 263 285 .. 255 289 .. 0.81 7 ? 2.4 0.1 0.26 1.8e+02 30 53 .. 303 326 .. 296 334 .. 0.83 8 ? 2.3 0.0 0.28 1.9e+02 23 52 .. 335 365 .. 328 369 .. 0.83 9 ? 2.4 0.1 0.26 1.8e+02 30 53 .. 383 406 .. 375 413 .. 0.83 10 ? 4.7 0.1 0.052 36 23 53 .. 415 446 .. 410 454 .. 0.84 11 ? -0.3 0.0 1.7 1.2e+03 23 48 .. 455 481 .. 449 487 .. 0.80 12 ? -1.0 0.0 2.8 1.9e+03 24 48 .. 496 521 .. 486 525 .. 0.76 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.36 CoV_NSP8 32 eqllkqlkkalniaksefdrda 53 ++ ++ ++k+lnia+ + drd+ FUN_000334-T1 65 PKAIECYEKSLNIAREARDRDS 86 678999**************97 PP == domain 2 score: 1.6 bits; conditional E-value: 0.44 CoV_NSP8 26 kangsseqllkqlkkalniaksefdrda 53 k +g+ ++ ++ ++k lnia+ + drd+ FUN_000334-T1 99 KCQGDFPKAIECYEKRLNIAREAGDRDN 126 55778899******************96 PP == domain 3 score: 1.9 bits; conditional E-value: 0.37 CoV_NSP8 28 ngsseqllkqlkkalniaksefdrd 52 +g+ ++ ++ ++k+lnia+ + drd FUN_000334-T1 141 QGDFPKAIECYEKSLNIAREAGDRD 165 5777999**************9998 PP == domain 4 score: 1.6 bits; conditional E-value: 0.45 CoV_NSP8 30 sseqllkqlkkalniaksefdrd 52 + ++ ++ ++k+lnia+ + drd FUN_000334-T1 183 DFPKAIECYEKSLNIARQAGDRD 205 3388999*************998 PP == domain 5 score: 1.4 bits; conditional E-value: 0.5 CoV_NSP8 30 sseqllkqlkkalniaksefdrd 52 + ++ ++ ++k+lnia+ + drd FUN_000334-T1 223 DFPKAIECYEKSLNIAREAGDRD 245 338999*************9998 PP == domain 6 score: 0.5 bits; conditional E-value: 0.97 CoV_NSP8 30 sseqllkqlkkalniaksefdrd 52 + ++ ++ ++k+lnia+ + dr+ FUN_000334-T1 263 DFPKAIECYEKSLNIAREAGDRN 285 3388999**********999997 PP == domain 7 score: 2.4 bits; conditional E-value: 0.26 CoV_NSP8 30 sseqllkqlkkalniaksefdrda 53 ++ + ++ ++k+lnia+ + drd+ FUN_000334-T1 303 DVLKAIECYEKSLNIAREARDRDS 326 45678999**************97 PP == domain 8 score: 2.3 bits; conditional E-value: 0.28 CoV_NSP8 23 eeakangss.eqllkqlkkalniaksefdrd 52 +a +++s ++ ++ ++k+lnia+ + dr+ FUN_000334-T1 335 GNAYKSQSDfPKAIECYEKSLNIAREAGDRN 365 567666666699*************999997 PP == domain 9 score: 2.4 bits; conditional E-value: 0.26 CoV_NSP8 30 sseqllkqlkkalniaksefdrda 53 ++ + ++ ++k+lnia+ + drd+ FUN_000334-T1 383 DVLKAIECYEKSLNIAREARDRDS 406 45678999**************97 PP == domain 10 score: 4.7 bits; conditional E-value: 0.052 CoV_NSP8 23 eeakangss.eqllkqlkkalniaksefdrda 53 +a +++s ++ ++ ++k+lnia+ + drd+ FUN_000334-T1 415 GNAYKSQSDfPKAIECYEKSLNIAREARDRDS 446 567666666699******************97 PP == domain 11 score: -0.3 bits; conditional E-value: 1.7 CoV_NSP8 23 eeakangss.eqllkqlkkalniakse 48 +a +++s ++ ++ ++k+lnia+ + FUN_000334-T1 455 GNAYKSQSDfPKAIECYEKSLNIAREA 481 567666666699************976 PP == domain 12 score: -1.0 bits; conditional E-value: 2.8 CoV_NSP8 24 eakangss.eqllkqlkkalniakse 48 a +++s ++ ++ ++k+lnia+ + FUN_000334-T1 496 SAYKSQSDfPKAIECYEKSLNIAREA 521 555555555999***********865 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.048 33 14 74 .. 24 84 .. 20 88 .. 0.83 2 ? 1.7 0.0 0.57 3.9e+02 13 74 .. 103 164 .. 90 166 .. 0.68 3 ? 0.1 0.1 1.8 1.2e+03 52 74 .. 222 244 .. 176 246 .. 0.61 4 ? 2.0 0.1 0.43 3e+02 10 74 .. 260 324 .. 251 328 .. 0.71 5 ? 1.0 0.2 0.9 6.2e+02 42 74 .. 332 364 .. 296 372 .. 0.61 6 ? 1.9 0.1 0.49 3.3e+02 12 73 .. 342 403 .. 330 410 .. 0.65 7 ? 0.9 0.3 1 7e+02 42 73 .. 412 443 .. 371 453 .. 0.61 8 ? 5.5 0.1 0.037 26 11 76 .. 461 526 .. 411 536 .. 0.70 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.048 ANAPC5 14 YqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +q+al++ + ++++ ++ a lnl i ++ ++ +A++ e + ++Are +D FUN_000334-T1 24 FQEALNKYEKQLKIATKAGDRAGVGWAYLNLGIAYYFHSDFPKAIECYEKSLNIAREARDR 84 5666666666666677777777778899*****9999999******************997 PP == domain 2 score: 1.7 bits; conditional E-value: 0.57 ANAPC5 13 dYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 d+++a+++ + ++ + ++ + + +nl + g+ +A++ e + ++Are +D FUN_000334-T1 103 DFPKAIECYEKRLNIAREAGDRDNEKDVYFNLGDAYNFQGDFPKAIECYEKSLNIAREAGDR 164 55555555555555555555555555555666666666688889999999999999999886 PP == domain 3 score: 0.1 bits; conditional E-value: 1.8 ANAPC5 52 ghneeAvkaieeaiklArenkDt 74 ++ +A++ e + ++Are +D FUN_000334-T1 222 SDFPKAIECYEKSLNIAREAGDR 244 44557888888888888888875 PP == domain 4 score: 2.0 bits; conditional E-value: 0.43 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +++d+++a+++ + ++ + ++++ a + + + ++ +A++ e + ++Are +D FUN_000334-T1 260 SQSDFPKAIECYEKSLNIAREAGDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIAREARDR 324 55677777777777777777777777666666666666777777778888888888888888875 PP == domain 5 score: 1.0 bits; conditional E-value: 0.9 ANAPC5 42 lnlailhadfghneeAvkaieeaiklArenkDt 74 +nl + + ++ +A++ e + ++Are +D FUN_000334-T1 332 FNLGNAYKSQSDFPKAIECYEKSLNIAREAGDR 364 444444444455566777777777777777776 PP == domain 6 score: 1.9 bits; conditional E-value: 0.49 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 +d+++a+++ + ++ + ++++ a + + + ++ +A++ e + ++Are +D FUN_000334-T1 342 SDFPKAIECYEKSLNIAREAGDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIAREARD 403 55666666666666666666666655556666666666666666777777777777777777 PP == domain 7 score: 0.9 bits; conditional E-value: 1 ANAPC5 42 lnlailhadfghneeAvkaieeaiklArenkD 73 +nl + + ++ +A++ e + ++Are +D FUN_000334-T1 412 FNLGNAYKSQSDFPKAIECYEKSLNIAREARD 443 44444444445555677777777777777776 PP == domain 8 score: 5.5 bits; conditional E-value: 0.037 ANAPC5 11 akdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 ++d+++a+++ + ++ + ++ s a +n + + + ++ +A++ e + ++Are +D+ FUN_000334-T1 461 QSDFPKAIECYEKSLNIAREAGDKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSLNIAREAGDQGG 526 456666666666666666666666666677777777777777777777777777777777777655 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 2.8 2e+03 126 150 .. 88 112 .. 61 115 .. 0.61 2 ? -0.9 0.0 3.6 2.5e+03 127 153 .] 129 155 .. 113 155 .. 0.80 3 ? -0.9 0.0 3.5 2.4e+03 133 153 .] 175 195 .. 167 195 .. 0.77 4 ? -0.0 0.0 1.9 1.3e+03 130 153 .] 212 235 .. 203 235 .. 0.80 5 ? -0.9 0.0 3.7 2.5e+03 133 153 .] 255 275 .. 248 275 .. 0.76 6 ? 4.6 0.1 0.07 49 120 153 .] 322 355 .. 294 355 .. 0.67 7 ? 6.4 0.2 0.021 14 76 153 .] 394 475 .. 381 475 .. 0.63 8 ? 1.6 0.0 0.59 4.1e+02 5 27 .. 494 516 .. 491 521 .. 0.66 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 2.8 ARM_TT21_4th 126 akiclqlAehaaserdyekaiklYk 150 +++ ++l++ + + d+ kai++Y FUN_000334-T1 88 KDVYFNLGNAYKCQGDFPKAIECYE 112 4555566666666666666666665 PP == domain 2 score: -0.9 bits; conditional E-value: 3.6 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 ++ ++l++ + + d+ kai++Y +L FUN_000334-T1 129 DVYFNLGDAYNFQGDFPKAIECYEKSL 155 667788888999999999999998765 PP == domain 3 score: -0.9 bits; conditional E-value: 3.5 ARM_TT21_4th 133 AehaaserdyekaiklYkeAL 153 + + s++d+ kai++Y +L FUN_000334-T1 175 GLAYNSQSDFPKAIECYEKSL 195 556788999999999998765 PP == domain 4 score: -0.0 bits; conditional E-value: 1.9 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 ++l+ + s++d+ kai++Y +L FUN_000334-T1 212 YSLGLAYNSQSDFPKAIECYEKSL 235 567778899999999999998776 PP == domain 5 score: -0.9 bits; conditional E-value: 3.7 ARM_TT21_4th 133 AehaaserdyekaiklYkeAL 153 + + s++d+ kai++Y +L FUN_000334-T1 255 GLAYNSQSDFPKAIECYEKSL 275 556788999999999998765 PP == domain 6 score: 4.6 bits; conditional E-value: 0.07 ARM_TT21_4th 120 eqkklaakiclqlAehaaserdyekaiklYkeAL 153 + + +++ ++l++ + s++d+ kai++Y +L FUN_000334-T1 322 RDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 355 34556688999*******************9876 PP == domain 7 score: 6.4 bits; conditional E-value: 0.021 ARM_TT21_4th 76 lllLlakvrksgkkeealetLkkakelqarvlkrvsveqpdav....eeqkklaakiclqlAehaaserdyekaiklYkeAL 153 l++ + r +++++++ +L +a++ q+ k +++ +++ ++ + +++ ++l++ + s++d+ kai++Y +L FUN_000334-T1 394 SLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSLNiareARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSL 475 5555555555666666777777777777777777765544432111133455667888888888888888888888887765 PP == domain 8 score: 1.6 bits; conditional E-value: 0.59 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 iG a+ ++ kAi+ Ye+ l+ FUN_000334-T1 494 IGSAYKSQSDFPKAIECYEKSLN 516 66666666677777777776665 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.0 0.0011 0.76 3 41 .. 580 618 .. 578 631 .. 0.87 2 ! 7.6 0.0 0.0053 3.7 45 83 .. 788 826 .. 762 848 .. 0.81 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.0011 Ras 3 vlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktv 41 +l+G++ GK+sl + +F+ + +sT+g+d + + FUN_000334-T1 580 MLIGQERSGKTSLKKSLQGLQFNPNEDSTVGIDADPSYF 618 79******************************9766555 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0053 Ras 45 gkevklqiwDTAGqerfralreayyrgaegillvydits 83 + ++ +wD AG + + +++++++ + llvyd+++ FUN_000334-T1 788 EDDIYSVMWDFAGESVYYETHQLFLTSRAIYLLVYDLSR 826 45667779****************************976 PP >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 1.2e-05 0.0082 11 81 .. 1470 1534 .. 1460 1535 .] 0.87 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 1.2e-05 Death 11 veplgkdWreLarklglseeeideiesenrdlrsqtyelLklWearegknatvgnLleaLrklgrrdaaek 81 ++ g++W+ +a++lgl+ ei+++ + r ++ + L +r + +v++L+++L ++g+ +a++ FUN_000334-T1 1470 LSG-GEEWKVVAERLGLNAKEIRYLDVRM---RNPCDAALSVVSQR--RCMNVDDLYDVLNECGMPVLADI 1534 456.89**********************9...**************..7777************9887776 PP >> Phage_tail_tube_init Putative phage tail tube initiator protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.1 0.22 1.5e+02 144 179 .. 71 106 .. 68 143 .. 0.74 2 ? 5.1 0.1 0.032 22 144 179 .. 311 346 .. 293 371 .. 0.79 3 ? 4.0 0.0 0.07 48 144 176 .. 391 423 .. 371 429 .. 0.88 4 ? 4.4 0.1 0.052 36 144 178 .. 431 465 .. 428 490 .. 0.82 5 ? -1.5 0.0 3.2 2.2e+03 144 178 .. 471 505 .. 467 525 .. 0.84 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.22 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksd 179 Ye +l + r+a + d+e+ v +++GN ++ ++ + FUN_000334-T1 71 YEKSLNIAREARDRDSEKDVYFNLGNAYKCQGDFPK 106 899999********************9987766553 PP == domain 2 score: 5.1 bits; conditional E-value: 0.032 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksd 179 Ye +l + r+a + d+e+ v +++GN ++s ++ + FUN_000334-T1 311 YEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPK 346 999**************************9988664 PP == domain 3 score: 4.0 bits; conditional E-value: 0.07 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpslee 176 Ye +l + r+a + d+e+ v +++GN ++s ++ FUN_000334-T1 391 YEKSLNIAREARDRDSEKDVYFNLGNAYKSQSD 423 999*************************99876 PP == domain 4 score: 4.4 bits; conditional E-value: 0.052 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeks 178 Ye +l + r+a + d+e+ v +++GN ++s ++ FUN_000334-T1 431 YEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFP 465 8999*************************998766 PP == domain 5 score: -1.5 bits; conditional E-value: 3.2 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeks 178 Ye +l + r+a++ +e + ++iG ++s ++ FUN_000334-T1 471 YEKSLNIAREAGDKVSEGRAYFNIGSAYKSQSDFP 505 8999**********************999988755 PP >> Cohesin_load Cohesin loading factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.27 1.9e+02 369 429 .. 140 197 .. 50 211 .. 0.64 2 ? 4.0 0.0 0.027 19 365 428 .. 176 236 .. 97 252 .. 0.70 3 ? 6.0 0.1 0.0063 4.4 396 522 .. 244 400 .. 207 443 .. 0.50 4 ? 2.0 0.0 0.1 72 305 428 .. 374 516 .. 370 538 .. 0.68 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.27 Cohesin_load 369 vrsdwtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqsplls 429 ++d+ ka e+ e+ + +++ + + + + ++y gl + ++ d +A ++y+++l+ FUN_000334-T1 140 FQGDFPKAIECYEKSLNIAREAG---DRDGEKDVYYGLGLAYNSQSDFPKAIECYEKSLNI 197 56777777666533333333333...55667778888888888888888888888777654 PP == domain 2 score: 4.0 bits; conditional E-value: 0.027 Cohesin_load 365 flalvrsdwtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspll 428 +++ ++sd+ ka e+ e+ + +++ + + + + ++y gl + ++ d +A ++y+++l+ FUN_000334-T1 176 LAYNSQSDFPKAIECYEKSLNIARQAG---DRDGEKDVYYSLGLAYNSQSDFPKAIECYEKSLN 236 344455555555444422222222222...3444555555555555555555555555555443 PP == domain 3 score: 6.0 bits; conditional E-value: 0.0063 Cohesin_load 396 kslktllhyleglyaqgtgdleaAlaiyqspllsl.lsseskttak..........dip.selailaalnlllilrdpshpdtselnelleklepl 479 + + ++y gl + ++ d +A ++y+++l+ ++ ++++++ + + + l+ + + + l + + + ++se + + + +++ FUN_000334-T1 244 RDGEKDVYYGLGLAYNSQSDFPKAIECYEKSLNIArEAGDRNMEGRayfgiglaykS-QsDVLKAIECYEKSLNIAREARDRDSEKDVYFNLGNAY 338 455555566666666666666666666655554442222222222233433333322.12444444444444422222222234444444444444 PP Cohesin_load 480 ...................clshpnkslraayslvkalqantqnslleakkslqealqaakk 522 + ++++++ ++ +l++ +q+ +l+a ++ ++l++a++ FUN_000334-T1 339 ksqsdfpkaiecyekslniAREAGDRNMEGRAYFGIGLAYKSQSDVLKAIECYEKSLNIARE 400 33333333333322222222223555555555555555555555555555555555555554 PP == domain 4 score: 2.0 bits; conditional E-value: 0.1 Cohesin_load 305 vaylpknsddk.kaekfleealklleklkkslk..epslsl.seasakaewlkvlrcylliylaf..................lalvrsdwtkase 378 + +++k+++d ka+++ e+ l++ ++ +++ + + + l +++++++++ k ++cy + + + ++ ++sd+ ka e FUN_000334-T1 374 IGLAYKSQSDVlKAIECYEKSLNIAREARDRDSekDVYFNLgNAYKSQSDFPKAIECYEKSLNIAreardrdsekdvyfnlgnAYKSQSDFPKAIE 469 566777777778899999999998888888766553333332455577777777777777666666777777777777777768888888888877 PP Cohesin_load 379 sleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspll 428 + e+ + +++ + +k +++ g + ++ d +A ++y+++l+ FUN_000334-T1 470 CYEKSLNIAREAG---DKVSEGRAYFNIGSAYKSQSDFPKAIECYEKSLN 516 7744444444444...5556777777778888888888888888877765 PP >> HEAT_Nup120 Nucleoporin Nup120, HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 1.9 1.3e+03 103 144 .. 66 107 .. 58 111 .. 0.88 2 ? -1.1 0.0 2.9 2e+03 87 144 .. 170 227 .. 137 236 .. 0.71 3 ? -1.1 0.0 3 2.1e+03 81 141 .. 204 264 .. 177 271 .. 0.53 4 ? 3.6 0.1 0.11 75 95 144 .. 298 347 .. 212 352 .. 0.91 5 ? 6.6 0.1 0.013 9 72 144 .. 395 467 .. 371 472 .. 0.77 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.9 HEAT_Nup120 103 yvaefarlAlqfkqkapdeddrsellsrlfkaalalgrfeeA 144 ++e+ + +l+++ +a d d+++++ +l +a+ g+f +A FUN_000334-T1 66 KAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKCQGDFPKA 107 6899999*****999999999***********9999999887 PP == domain 2 score: -1.1 bits; conditional E-value: 2.9 HEAT_Nup120 87 YYahvasLfekakaysyvaefarlAlqfkqkapdeddrsellsrlfkaalalgrfeeA 144 Y + + +++ + ++e+ + +l+++ +a d d ++++ ++l a+ + ++f +A FUN_000334-T1 170 VYYGLGLAYNSQSDFPKAIECYEKSLNIARQAGDRDGEKDVYYSLGLAYNSQSDFPKA 227 4555555566677777788888888888666667777888888888888888888776 PP == domain 3 score: -1.1 bits; conditional E-value: 3 HEAT_Nup120 81 nsglpkYYahvasLfekakaysyvaefarlAlqfkqkapdeddrsellsrlfkaalalgrf 141 +g+ + Y + + +++ + ++e+ + +l+++ +a d d ++++ + l a+ + ++f FUN_000334-T1 204 RDGEKDVYYSLGLAYNSQSDFPKAIECYEKSLNIAREAGDRDGEKDVYYGLGLAYNSQSDF 264 3444444444444555555555666666666666444455555566666665555555555 PP == domain 4 score: 3.6 bits; conditional E-value: 0.11 HEAT_Nup120 95 fekakaysyvaefarlAlqfkqkapdeddrsellsrlfkaalalgrfeeA 144 +++++ ++e+ + +l+++ +a d d+++++ +l +a+ + ++f +A FUN_000334-T1 298 YKSQSDVLKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKA 347 67788888999*********9999999*******************9988 PP == domain 5 score: 6.6 bits; conditional E-value: 0.013 HEAT_Nup120 72 ldvlepnalnsglpkYYahvasLfekakaysyvaefarlAlqfkqkapdeddrsellsrlfkaalalgrfeeA 144 l+++ + +++ + Y + + +++++ + ++e+ + +l+++ +a d d+++++ +l +a+ + ++f +A FUN_000334-T1 395 LNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKA 467 4445444456677777888888889999999999999999999888999999999999999999999999877 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00053 0.37 4 27 .. 579 602 .. 575 614 .. 0.87 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00053 PduV-EutP 4 illiGkvgsGKttLtqalkgeelk 27 ++liG+ sGKt+L+++l+g++++ FUN_000334-T1 579 MMLIGQERSGKTSLKKSLQGLQFN 602 69*****************98875 PP >> RE_NgoFVII_C NgoFVII C-terminal B3-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 1.5 1e+03 23 57 .. 73 106 .. 60 111 .. 0.84 2 ? 1.5 0.0 0.48 3.3e+02 20 57 .. 310 346 .. 299 352 .. 0.83 3 ? 1.4 0.0 0.51 3.6e+02 19 57 .. 389 426 .. 374 429 .. 0.83 4 ? 0.9 0.0 0.76 5.2e+02 25 57 .. 434 466 .. 426 472 .. 0.85 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 1.5 RE_NgoFVII_C 23 kSglNvgqareqrkaprdaYirvpkeitrsefype 57 k lN++ + ++r+ ++d Y +++++ ++ +p+ FUN_000334-T1 73 K-SLNIAREARDRDSEKDVYFNLGNAYKCQGDFPK 106 4.49**999999999********999998888886 PP == domain 2 score: 1.5 bits; conditional E-value: 0.48 RE_NgoFVII_C 20 veekSglNvgqareqrkaprdaYirvpkeitrsefype 57 ekS lN++ + ++r+ ++d Y +++++ ++ +p+ FUN_000334-T1 310 CYEKS-LNIAREARDRDSEKDVYFNLGNAYKSQSDFPK 346 45555.9**999999999**********9999999987 PP == domain 3 score: 1.4 bits; conditional E-value: 0.51 RE_NgoFVII_C 19 eveekSglNvgqareqrkaprdaYirvpkeitrsefype 57 e ekS lN++ + ++r+ ++d Y +++++ ++ +p+ FUN_000334-T1 389 ECYEKS-LNIAREARDRDSEKDVYFNLGNAYKSQSDFPK 426 455555.9**999999999**********9999999986 PP == domain 4 score: 0.9 bits; conditional E-value: 0.76 RE_NgoFVII_C 25 glNvgqareqrkaprdaYirvpkeitrsefype 57 lN++ + ++r+ ++d Y +++++ ++ +p+ FUN_000334-T1 434 SLNIAREARDRDSEKDVYFNLGNAYKSQSDFPK 466 49**999999999**********9999999987 PP >> DMA DMRTA motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.44 3.1e+02 25 36 .. 99 110 .. 98 111 .. 0.92 2 ? -2.7 0.0 9.4 6.5e+03 26 36 .. 140 150 .. 139 150 .. 0.88 3 ? 2.3 0.0 0.26 1.8e+02 29 36 .. 303 310 .. 301 311 .. 0.91 4 ? 2.3 0.0 0.26 1.8e+02 29 36 .. 383 390 .. 381 391 .. 0.91 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.44 DMA 25 rCkGDVvqAIEq 36 C+GD +AIE+ FUN_000334-T1 99 KCQGDFPKAIEC 110 5**********8 PP == domain 2 score: -2.7 bits; conditional E-value: 9.4 DMA 26 CkGDVvqAIEq 36 ++GD +AIE+ FUN_000334-T1 140 FQGDFPKAIEC 150 789999****8 PP == domain 3 score: 2.3 bits; conditional E-value: 0.26 DMA 29 DVvqAIEq 36 DV++AIE+ FUN_000334-T1 303 DVLKAIEC 310 9******8 PP == domain 4 score: 2.3 bits; conditional E-value: 0.26 DMA 29 DVvqAIEq 36 DV++AIE+ FUN_000334-T1 383 DVLKAIEC 390 9******8 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.58 4e+02 5 23 .. 92 110 .. 90 113 .. 0.83 2 ? 5.5 0.0 0.068 47 5 23 .. 132 150 .. 130 153 .. 0.84 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.58 TPR_4 5 laLArallalGdldeAral 23 +L+ a+ +Gd++ A + FUN_000334-T1 92 FNLGNAYKCQGDFPKAIEC 110 79************99665 PP == domain 2 score: 5.5 bits; conditional E-value: 0.068 TPR_4 5 laLArallalGdldeAral 23 +L+ a+ +Gd++ A + FUN_000334-T1 132 FNLGDAYNFQGDFPKAIEC 150 79************99665 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.14 96 66 114 .. 61 109 .. 60 121 .. 0.86 2 ? 1.5 0.0 0.57 3.9e+02 73 114 .. 108 149 .. 104 159 .. 0.88 3 ? 0.1 0.0 1.6 1.1e+03 68 113 .. 183 228 .. 178 241 .. 0.81 4 ? -2.0 0.0 6.7 4.6e+03 68 96 .. 263 291 .. 246 320 .. 0.78 5 ? -0.9 0.0 3.1 2.1e+03 70 113 .. 305 348 .. 297 361 .. 0.81 6 ? -0.9 0.0 3.1 2.1e+03 71 113 .. 386 428 .. 379 442 .. 0.80 7 ? -0.6 0.0 2.5 1.8e+03 68 113 .. 423 468 .. 417 480 .. 0.82 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.14 Ulvan_lyase_2nd 66 hrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpaik 114 h ++ + e ye ln+a+ ++ e+++ +L +ay+ +G++ +ai+ FUN_000334-T1 61 HSDFPKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKCQGDFPKAIE 109 5567778899*********************************999884 PP == domain 2 score: 1.5 bits; conditional E-value: 0.57 Ulvan_lyase_2nd 73 eelyelalnlakrkgyteleekaealLkqaydaeGgykpaik 114 e ye ln+a+ g ++ e+++ +L ay+ +G++ +ai+ FUN_000334-T1 108 IECYEKRLNIAREAGDRDNEKDVYFNLGDAYNFQGDFPKAIE 149 5789********************************998875 PP == domain 3 score: 0.1 bits; conditional E-value: 1.6 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 ++ + e ye ln+a++ g ++ e+++ L ay+++ ++ +ai FUN_000334-T1 183 DFPKAIECYEKSLNIARQAGDRDGEKDVYYSLGLAYNSQSDFPKAI 228 56677899***************99999999998888776666655 PP == domain 4 score: -2.0 bits; conditional E-value: 6.7 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekae 96 ++ + e ye ln+a+ g +++e +a FUN_000334-T1 263 DFPKAIECYEKSLNIAREAGDRNMEGRAY 291 56677789999999999999999887765 PP == domain 5 score: -0.9 bits; conditional E-value: 3.1 Ulvan_lyase_2nd 70 deteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 + e ye ln+a+ ++ e+++ +L +ay+++ ++ +ai FUN_000334-T1 305 LKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAI 348 56678999999***999999999999999999998877666655 PP == domain 6 score: -0.9 bits; conditional E-value: 3.1 Ulvan_lyase_2nd 71 eteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 + e ye ln+a+ ++ e+++ +L +ay+++ ++ +ai FUN_000334-T1 386 KAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAI 428 667899999****999999999999999999998877766665 PP == domain 7 score: -0.6 bits; conditional E-value: 2.5 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 ++ + e ye ln+a+ ++ e+++ +L +ay+++ ++ +ai FUN_000334-T1 423 DFPKAIECYEKSLNIAREARDRDSEKDVYFNLGNAYKSQSDFPKAI 468 56677899*******************9999999998887766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1535 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 981 (0.0384028); expected 510.9 (0.02) Passed bias filter: 657 (0.0257193); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 38 (0.00148757); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 37 [number of targets reported over threshold] # CPU time: 0.63u 0.41s 00:00:01.04 Elapsed: 00:00:00.47 # Mc/sec: 13158.01 // Query: FUN_000335-T1 [L=1234] Description: FUN_000335 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-41 138.4 6.1 4.5e-12 46.5 0.0 5.0 7 TPR_12 Tetratricopeptide repeat 3.8e-20 71.3 10.2 1.7e-05 24.9 0.0 6.9 7 TPR_1 Tetratricopeptide repeat 5.7e-18 65.7 0.7 1.2e-17 64.6 0.7 1.6 1 COR-A C-terminal of Roc, COR-A domain 7.2e-17 60.5 7.5 0.00018 21.9 0.0 6.8 6 TPR_2 Tetratricopeptide repeat 1.5e-13 51.5 0.2 7.8e-06 26.6 0.0 2.9 3 Roc Ras of Complex, Roc, domain of DAPkinase 1.7e-13 50.0 0.1 0.0071 16.8 0.0 5.2 4 TPR_7 Tetratricopeptide repeat 1.5e-11 44.0 7.2 0.0042 17.6 0.1 6.3 6 TPR_8 Tetratricopeptide repeat 2e-08 34.4 0.0 0.041 14.4 0.0 4.4 4 TPR_10 Tetratricopeptide repeat 2.1e-06 28.2 0.1 0.07 13.7 0.0 4.0 3 ANAPC5 Anaphase-promoting complex subunit 5 3.1e-06 27.4 0.0 5.7e-06 26.5 0.0 1.3 1 SNAP Soluble NSF attachment protein, SNAP 0.00017 22.5 0.7 3.3 8.7 0.0 4.4 5 TPR_16 Tetratricopeptide repeat 0.00025 21.9 1.0 6 8.4 0.0 5.3 4 TPR_14 Tetratricopeptide repeat 0.00049 20.2 0.1 1.5 8.8 0.0 2.4 2 Ras Ras family 0.0009 20.2 0.0 22 6.4 0.0 5.4 5 TPR_6 Tetratricopeptide repeat 0.0018 18.5 0.0 1.1 9.4 0.0 2.5 2 RPN7 26S proteasome subunit RPN7 0.0021 18.7 0.5 54 4.9 0.0 5.5 5 TPR_17 Tetratricopeptide repeat 0.0037 17.8 0.0 0.012 16.2 0.0 1.9 1 Death Death domain ------ inclusion threshold ------ 0.016 15.1 0.0 1.1 9.3 0.0 3.6 4 SHNi-TPR SHNi-TPR 0.023 14.4 0.0 0.34 10.6 0.0 2.2 2 TPR_MalT MalT-like TPR region 0.077 13.3 0.0 0.17 12.2 0.0 1.5 1 PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.086 13.0 10.3 9.4 6.5 0.2 6.6 6 TPR_11 TPR repeat 0.091 12.4 0.1 0.16 11.6 0.1 1.4 1 G-alpha G-protein alpha subunit 0.17 12.5 0.6 27 5.4 0.0 3.0 2 TPR_9 Tetratricopeptide repeat 0.18 12.1 0.1 16 5.8 0.1 3.7 4 DUF7380 Domain of unknown function (DUF7380) Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.1 1.2e-05 0.013 25 77 .] 28 78 .. 27 78 .. 0.96 2 ! 40.7 0.0 2.6e-13 2.8e-10 15 77 .] 58 118 .. 46 118 .. 0.90 3 ! 42.6 0.1 6.6e-14 7.1e-11 5 76 .. 88 157 .. 84 158 .. 0.94 4 ! 46.5 0.0 4.2e-15 4.5e-12 5 76 .. 128 197 .. 124 198 .. 0.95 5 ! 27.8 0.0 2.8e-09 3e-06 4 67 .. 167 228 .. 164 229 .. 0.96 6 ? -2.1 0.0 6.1 6.5e+03 63 72 .. 256 265 .. 254 266 .. 0.67 7 ? -1.7 0.1 4.4 4.7e+03 54 77 .] 781 804 .. 780 804 .. 0.89 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.2e-05 TPR_12 25 llekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ek l++a ++++p + + a+ Lg++y ++ +A++ +e++l+ia++ FUN_000335-T1 28 HHEKHLNIAGEAHNPAR--EGDAHLSLGIAYDSHSNFPKAIKGYEKSLNIARE 78 89************999..999****************************986 PP == domain 2 score: 40.7 bits; conditional E-value: 2.6e-13 TPR_12 15 rlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ +A++ +ek+l++a+++ +d+ + a+ nL ++y a gd+ +A+e++e++l+ia++ FUN_000335-T1 58 SHSNFPKAIKGYEKSLNIAREA--GDRAREGDAYLNLLIAYKAIGDFPKAIECFEKSLDIARE 118 556899****************..9999********************************986 PP == domain 3 score: 42.6 bits; conditional E-value: 6.6e-14 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl ++ + g++ +A+e++ek+l++a+++ +d+ + a+ nLg++y+ g + e +e +e++l+ia+ FUN_000335-T1 88 AYLNLLIAYKAIGDFPKAIECFEKSLDIAREA--GDRAKEGDAYLNLGTAYEFHGGFSEGIESYEKSLDIAR 157 66777789999*********************..99**********************************98 PP == domain 4 score: 46.5 bits; conditional E-value: 4.2e-15 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ ++ g + e +e +ek+l++a+r+ +d+ + a+ nLg++++ g++ +A+e++e++l+ia FUN_000335-T1 128 AYLNLGTAYEFHGGFSEGIESYEKSLDIARRV--GDRTSEGDAYLNLGIAHQSHGEFPKAIECFEESLNIAS 197 899*****************************..88999******************************985 PP == domain 5 score: 27.8 bits; conditional E-value: 2.8e-09 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlel 67 a++nl+ +++ g++ +A+e++e++l++a+++ +d+ + ++a + L + y+algd+ +A+e+ FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEESLNIASEA--GDWAGISRAKQYLRISYFALGDFLKAVEY 228 5899***************************99..9*************************987 PP == domain 6 score: -2.1 bits; conditional E-value: 6.1 TPR_12 63 eAlelleqal 72 +A+e++++al FUN_000335-T1 256 KAREAYNKAL 265 5777777776 PP == domain 7 score: -1.7 bits; conditional E-value: 4.4 TPR_12 54 lylalgdyeeAlelleqaleiaek 77 l++a g+ +e + +e+ ++i+ek FUN_000335-T1 781 LQHAWGQIAEERHTFERLIAIMEK 804 568999***************986 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 6.4e-05 0.068 2 31 .. 47 76 .. 46 78 .. 0.92 2 ! 17.9 0.1 2.5e-06 0.0027 4 31 .. 89 116 .. 86 118 .. 0.84 3 ! 10.7 0.0 0.0005 0.53 2 31 .. 127 156 .. 126 158 .. 0.94 4 ! 24.9 0.0 1.6e-08 1.7e-05 2 30 .. 167 195 .. 166 198 .. 0.93 5 ? 2.1 0.0 0.26 2.8e+02 10 23 .. 215 228 .. 214 228 .. 0.92 6 ? 2.3 0.1 0.22 2.3e+02 19 29 .. 256 266 .. 255 267 .. 0.90 7 ? -2.8 0.0 9.3 9.9e+03 24 29 .. 674 679 .. 673 680 .. 0.61 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 6.4e-05 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lG ay + ++ +A++ yek L + FUN_000335-T1 47 DAHLSLGIAYDSHSNFPKAIKGYEKSLNIA 76 799**********************99775 PP == domain 2 score: 17.9 bits; conditional E-value: 2.5e-06 TPR_1 4 lynlGnayfklgkydeAleyyekALeln 31 + nl ay + g++ +A+e++ek L + FUN_000335-T1 89 YLNLLIAYKAIGDFPKAIECFEKSLDIA 116 5555579******************986 PP == domain 3 score: 10.7 bits; conditional E-value: 0.0005 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay g + e +e yek L + FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIA 156 79*************************986 PP == domain 4 score: 24.9 bits; conditional E-value: 1.6e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG a+++ g++ +A+e++e+ L + FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEESLNI 195 79***********************9976 PP == domain 5 score: 2.1 bits; conditional E-value: 0.26 TPR_1 10 ayfklgkydeAley 23 yf+lg++ +A+ey FUN_000335-T1 215 SYFALGDFLKAVEY 228 6***********98 PP == domain 6 score: 2.3 bits; conditional E-value: 0.22 TPR_1 19 eAleyyekALe 29 +A e+y+kAL+ FUN_000335-T1 256 KAREAYNKALR 266 89*******96 PP == domain 7 score: -2.8 bits; conditional E-value: 9.3 TPR_1 24 yekALe 29 yekAL+ FUN_000335-T1 674 YEKALQ 679 666665 PP >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.6 0.7 1.1e-20 1.2e-17 1 142 [] 668 828 .. 668 828 .. 0.91 Alignments for each domain: == domain 1 score: 64.6 bits; conditional E-value: 1.1e-20 COR-A 1 Pkswlevreelee.kkseknyisleeyreicke.nglkeeeeqdrllkfLhdlGvllyfqddeelkdlviLkpeWlteavykvlds.......... 84 P +wl+++++l+ ++ +++i++e+ +i++e +++ +++e ++l+fLhd l++f+d el++lv+L+p+Wl+++ +v++ FUN_000335-T1 668 PIKWLRYEKALQVtLAEGHKCITIEHAEQIASEvCQIGDRQEFVTMLDFLHDQRILIHFDDTVELNKLVVLDPQWLIDVFKAVITVkpfhlqekgf 763 89**********988999************98658**************************99**********************99999999999 PP COR-A 85 ...kevlkkkGllkeedlkkiwkek.ypaeehdellrlmekfelcyelek...eeedtylvpqlL 142 ++l+++G+l+e+ l++ w + ++++ + l+ +mekf l + ++ +++ylvp++L FUN_000335-T1 764 kdmWRTLEREGILEEKLLQHAWGQIaEERHTFERLIAIMEKFSLLCSWSSsdePCSKKYLVPSML 828 7776677899*************97788888899**********99988865545689****987 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.0 0.0012 1.2 2 32 .. 47 77 .. 46 79 .. 0.92 2 ! 13.9 0.2 6.1e-05 0.065 10 32 .. 95 117 .. 87 119 .. 0.90 3 ! 7.4 0.0 0.0073 7.8 2 31 .. 127 156 .. 126 158 .. 0.93 4 ! 21.9 0.0 1.7e-07 0.00018 2 31 .. 167 196 .. 166 199 .. 0.93 5 ? 1.6 0.0 0.51 5.4e+02 10 23 .. 215 228 .. 214 228 .. 0.91 6 ? 3.6 0.0 0.12 1.3e+02 19 29 .. 256 266 .. 255 270 .. 0.90 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0012 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ lG ay ++ +A++ yek+l ++ FUN_000335-T1 47 DAHLSLGIAYDSHSNFPKAIKGYEKSLNIAR 77 68999**********************9875 PP == domain 2 score: 13.9 bits; conditional E-value: 6.1e-05 TPR_2 10 ayyklgdyeeAleayekAleldP 32 ay + gd+ +A+e++ek+l ++ FUN_000335-T1 95 AYKAIGDFPKAIECFEKSLDIAR 117 89999**************9976 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0073 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlG ay+ g + e +e yek+l ++ FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIA 156 699************************986 PP == domain 4 score: 21.9 bits; conditional E-value: 1.7e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlG a+ g++ +A+e++e++l ++ FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEESLNIA 196 69*************************987 PP == domain 5 score: 1.6 bits; conditional E-value: 0.51 TPR_2 10 ayyklgdyeeAlea 23 +y++lgd+ +A+e+ FUN_000335-T1 215 SYFALGDFLKAVEY 228 79*********997 PP == domain 6 score: 3.6 bits; conditional E-value: 0.12 TPR_2 19 eAleayekAle 29 +A+eay+kAl+ FUN_000335-T1 256 KAREAYNKALR 266 8*********8 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.0 2.5e-07 0.00027 2 44 .. 277 318 .. 276 363 .. 0.86 2 ! 26.6 0.0 7.4e-09 7.8e-06 47 91 .. 480 525 .. 453 550 .. 0.75 3 ? -2.6 0.0 8.6 9.1e+03 59 86 .. 876 904 .. 874 909 .. 0.74 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 2.5e-07 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskeltki 44 ++l+G+ + GKtsl k + +f+++e+ t+g+d+ + ++ + FUN_000335-T1 277 IMLIGQDRSGKTSLKKSLQGLQFNPNEDGTVGIDVDPSYFK-V 318 89*********************************887653.3 PP == domain 2 score: 26.6 bits; conditional E-value: 7.4e-09 Roc 47 lendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.srs 91 +++ + +i +WD+aG+ ++++h+l+++++a+++lv+d +r+ FUN_000335-T1 480 VDKMGSEDDIYSVLWDFAGESVYYETHQLFLTSKAIYLLVYDlNRD 525 33333445677889****************************6443 PP == domain 3 score: -2.6 bits; conditional E-value: 8.6 Roc 59 niWDtaGqerfrslhplyyre.aaaailv 86 ++W ta + +++ +++y + +++ +++ FUN_000335-T1 876 DFWSTANPKLYKNFARFYTAKdKNVSVIL 904 5899*************996504454544 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.0027 2.9 1 36 [] 48 83 .. 48 83 .. 0.95 2 ! 16.8 0.0 6.7e-06 0.0071 1 36 [] 88 123 .. 88 123 .. 0.92 3 ? 6.2 0.0 0.017 18 1 35 [. 128 162 .. 128 163 .. 0.95 4 ! 11.8 0.0 0.00027 0.29 1 33 [. 168 200 .. 168 201 .. 0.91 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0027 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +y + ++ +Ai+ ye+ L +a++ +dr+ FUN_000335-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSLNIAREAGDRA 83 7899*****************************985 PP == domain 2 score: 16.8 bits; conditional E-value: 6.7e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L +y + Gd+ +Ai+++e+ L++a++ +dr+ FUN_000335-T1 88 AYLNLLIAYKAIGDFPKAIECFEKSLDIAREAGDRA 123 56788889*************************985 PP == domain 3 score: 6.2 bits; conditional E-value: 0.017 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y+ G + e i+ ye+ L++a++ +dr FUN_000335-T1 128 AYLNLGTAYEFHGGFSEGIESYEKSLDIARRVGDR 162 789******************************98 PP == domain 4 score: 11.8 bits; conditional E-value: 0.00027 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpe 33 a+++L+ ++++ G++ +Ai+++e+ L +a + + FUN_000335-T1 168 AYLNLGIAHQSHGEFPKAIECFEESLNIASEAG 200 789*********************999987765 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 2.1 2.2e+03 3 32 .. 48 77 .. 46 78 .. 0.84 2 ! 17.6 0.1 3.9e-06 0.0042 2 32 .. 87 117 .. 86 118 .. 0.95 3 ! 11.7 0.0 0.00031 0.33 2 32 .. 127 157 .. 126 158 .. 0.95 4 ! 11.2 0.0 0.00046 0.49 2 31 .. 167 196 .. 166 198 .. 0.94 5 ? -0.2 0.0 2.1 2.2e+03 11 23 .. 216 228 .. 215 228 .. 0.89 6 ? -0.6 0.2 2.7 2.9e+03 19 28 .. 256 265 .. 256 266 .. 0.89 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 2.1 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 a++ lG +y + ++ +A++ yek+l +++ FUN_000335-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSLNIAR 77 67788888999899999*********9986 PP == domain 2 score: 17.6 bits; conditional E-value: 3.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nl +y+ gd+ +A+e++ek+l++++ FUN_000335-T1 87 DAYLNLLIAYKAIGDFPKAIECFEKSLDIAR 117 69**************************987 PP == domain 3 score: 11.7 bits; conditional E-value: 0.00031 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y+ g + e +e+yek+l++++ FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIAR 157 69**************************986 PP == domain 4 score: 11.2 bits; conditional E-value: 0.00046 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay+nlG ++++ g++ +A+e++e++l ++ FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEESLNIA 196 69*************************997 PP == domain 5 score: -0.2 bits; conditional E-value: 2.1 TPR_8 11 ylklgdyeeAkey 23 y lgd+ +A+ey FUN_000335-T1 216 YFALGDFLKAVEY 228 89999*9999998 PP == domain 6 score: -0.6 bits; conditional E-value: 2.7 TPR_8 19 eAkeyyekal 28 +A+e+y+kal FUN_000335-T1 256 KAREAYNKAL 265 69*******9 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 2.7 2.8e+03 8 34 .. 52 78 .. 50 79 .. 0.85 2 ! 6.7 0.0 0.0097 10 6 35 .. 90 119 .. 87 119 .. 0.86 3 ! 7.5 0.0 0.0057 6 3 35 .. 127 159 .. 126 159 .. 0.96 4 ! 14.4 0.0 3.8e-05 0.041 3 32 .. 167 196 .. 166 199 .. 0.92 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2.7 TPR_10 8 LanalraqgryeeAeelleealairer 34 L+ a+ + ++ A + +e++l i+++ FUN_000335-T1 52 LGIAYDSHSNFPKAIKGYEKSLNIARE 78 899999999999999999999999987 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0097 TPR_10 6 nnLanalraqgryeeAeelleealairerv 35 nL a+ a g++ A e +e++l+i++++ FUN_000335-T1 90 LNLLIAYKAIGDFPKAIECFEKSLDIAREA 119 55557999******************9985 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0057 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL++a+ g + e e +e++l+i++rv FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIARRV 159 5899***************************97 PP == domain 4 score: 14.4 bits; conditional E-value: 3.8e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealair 32 +++ nL+ a+++ g++ A e +ee+l i+ FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEESLNIA 196 5899***********************986 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.27 2.8e+02 40 74 .. 48 82 .. 19 85 .. 0.82 2 ! 7.1 0.0 0.0075 8 40 75 .. 88 123 .. 86 125 .. 0.94 3 ! 13.7 0.0 6.6e-05 0.07 18 82 .. 146 210 .. 128 214 .. 0.81 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.27 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDt 74 a l+l i + + ++ +A+k e + ++Are +D FUN_000335-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSLNIAREAGDR 82 55677777777778889999999999999999997 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0075 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDta 75 a lnl i + ++g+ +A++ +e + +Are +D a FUN_000335-T1 88 AYLNLLIAYKAIGDFPKAIECFEKSLDIAREAGDRA 123 789******************************975 PP == domain 3 score: 13.7 bits; conditional E-value: 6.6e-05 ANAPC5 18 ldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtacLnlals 82 ++s + D++ +++s a lnl i h++ g+ +A++ +ee+ ++A e +D a ++ a + FUN_000335-T1 146 IESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGEFPKAIECFEESLNIASEAGDWAGISRAKQ 210 555556666666666666666799********************************998877665 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.0 5.3e-09 5.7e-06 44 180 .. 55 191 .. 46 200 .. 0.95 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 5.3e-09 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 ay + ++ +A + ++k ++ ++++++ ++ay++ +yk d +A+e++ek+ +i e+g + ++ + +++ ye + +++ ie+Y FUN_000335-T1 55 AYDSHSNFPKAIKGYEKSLNIAREAGDRAREGDAYLNLLIAYKAIgDFPKAIECFEKSLDIAREAGDRAKEGDAYLNLGTAYEFH-GGFSEGIESY 149 5667789999*********************************987999***********************************9.********** PP SNAP 139 eqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e++ d+ + + ++ ++l++ + ++++++kAie +e+ FUN_000335-T1 150 EKSLDIARRVGDRTSEGDAYLNLGIAHQSHGEFPKAIECFEE 191 ****************************************97 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.12 1.3e+02 28 54 .. 43 70 .. 33 81 .. 0.80 2 ? 4.0 0.1 0.094 1e+02 21 61 .. 74 116 .. 70 120 .. 0.78 3 ? 6.2 0.0 0.02 21 5 59 .. 94 154 .. 90 158 .. 0.81 4 ! 8.7 0.0 0.0031 3.3 2 58 .. 131 193 .. 130 200 .. 0.82 5 ? -0.3 0.0 2.2 2.3e+03 48 61 .. 255 268 .. 253 271 .. 0.69 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.12 TPR_16 28 PeaaaAllglGlallrqgrlaeAa.aay 54 + +A+l lG a+ ++++A+ + FUN_000335-T1 43 AREGDAHLSLGIAYDSHSNFPKAIkGYE 70 67889******************95544 PP == domain 2 score: 4.0 bits; conditional E-value: 0.094 TPR_16 21 eaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalraa 61 a++++ + +A+l+l a+ + g++++A++ +++ l++a FUN_000335-T1 74 NIAREAGdrAREGDAYLNLLIAYKAIGDFPKAIECFEKSLDIA 116 5566666777788999999999999999999999998888665 PP == domain 3 score: 6.2 bits; conditional E-value: 0.02 TPR_16 5 raalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalr 59 a+ a gd++ A++++e l+ +A+l+lG a++ g + e ++ y++ l+ FUN_000335-T1 94 IAYKAIGDFPKAIECFEKSLDIAreagdrAKEGDAYLNLGTAYEFHGGFSEGIESYEKSLD 154 6788899******99999888777888999999*********9977777777777777665 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0031 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +g + + ++ +e l+ + +A+l+lG a+ g++++A++ +++ l FUN_000335-T1 131 NLGTAYEFHGGFSEGIESYEKSLDIArrvgdrTSEGDAYLNLGIAHQSHGEFPKAIECFEESL 193 6788888888888888888887776667789966899*******************9988866 PP == domain 5 score: -0.3 bits; conditional E-value: 2.2 TPR_16 48 aeAaaayraalraa 61 ++A++ay++alr++ FUN_000335-T1 255 PKAREAYNKALREG 268 46777777777665 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 0.0 0.0057 6 2 30 .. 87 115 .. 86 123 .. 0.88 2 ? 0.1 0.0 2.8 3e+03 2 29 .. 127 154 .. 126 158 .. 0.88 3 ? 5.7 0.0 0.041 44 2 28 .. 167 193 .. 166 203 .. 0.89 4 ? -0.3 0.0 3.7 3.9e+03 19 31 .. 256 268 .. 253 273 .. 0.83 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0057 TPR_14 2 eawlalarallalGdpdeAlelleralal 30 +a+l l+ a+ a Gd+ +A+e++e+ l FUN_000335-T1 87 DAYLNLLIAYKAIGDFPKAIECFEKSLDI 115 68999*******************98875 PP == domain 2 score: 0.1 bits; conditional E-value: 2.8 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+l l+ a++ G ++e +e +e+ l FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLD 154 68999***************99998775 PP == domain 3 score: 5.7 bits; conditional E-value: 0.041 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+l l+ a+ G++ +A+e++e+ l FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEESL 193 68999*******************987 PP == domain 4 score: -0.3 bits; conditional E-value: 3.7 TPR_14 19 eAlelleralald 31 +A+e++++al+ FUN_000335-T1 256 KAREAYNKALREG 268 8********9976 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.0014 1.5 2 47 .. 277 322 .. 276 336 .. 0.86 2 ! 8.7 0.0 0.0015 1.6 45 83 .. 486 524 .. 461 546 .. 0.83 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0014 Ras 2 lvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgke 47 ++l+G+ GK+sl + +F+ + + T+g+d + ++v + FUN_000335-T1 277 IMLIGQDRSGKTSLKKSLQGLQFNPNEDGTVGIDVDPSYFKVTTEV 322 689*******************************987777766555 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0015 Ras 45 gkevklqiwDTAGqerfralreayyrgaegillvydits 83 + ++ +wD AG + + +++++++ + llvyd+++ FUN_000335-T1 486 EDDIYSVLWDFAGESVYYETHQLFLTSKAIYLLVYDLNR 524 45666789****************************986 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 3.4 3.6e+03 1 25 [. 47 71 .. 47 74 .. 0.88 2 ? 2.6 0.0 0.34 3.7e+02 8 25 .. 94 111 .. 87 115 .. 0.80 3 ? 2.6 0.0 0.35 3.8e+02 1 25 [. 127 151 .. 127 154 .. 0.87 4 ? 6.4 0.0 0.021 22 1 25 [. 167 191 .. 167 195 .. 0.93 5 ? -1.5 0.0 7.4 7.8e+03 9 22 .. 215 228 .. 214 228 .. 0.88 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.4 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA l l+ +y ++ +A++ +++ FUN_000335-T1 47 DAHLSLGIAYDSHSNFPKAIKGYEK 71 688999*****977*******9997 PP == domain 2 score: 2.6 bits; conditional E-value: 0.34 TPR_6 8 lsylelgdkdeAkaalqr 25 +y++ gd+ +A++ +++ FUN_000335-T1 94 IAYKAIGDFPKAIECFEK 111 689999**********98 PP == domain 3 score: 2.6 bits; conditional E-value: 0.35 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +y+ g + e ++ +++ FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEK 151 8**********98888888888886 PP == domain 4 score: 6.4 bits; conditional E-value: 0.021 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +++ g++ +A++ +++ FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIECFEE 191 8***********99********996 PP == domain 5 score: -1.5 bits; conditional E-value: 7.4 TPR_6 9 sylelgdkdeAkaa 22 sy++lgd+ +A+++ FUN_000335-T1 215 SYFALGDFLKAVEY 228 8*******999985 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0077 8.2 19 65 .. 69 115 .. 59 125 .. 0.80 2 ! 9.4 0.0 0.001 1.1 37 134 .. 127 227 .. 113 229 .. 0.89 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0077 RPN7 19 LeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarek 65 e+ l+ a+e +a+++l y +igd+ +A++++e+ ++ FUN_000335-T1 69 YEKSLNIAREAGDRAREGDAYLNLLIAYKAIGDFPKAIECFEKSLDI 115 56666666666667777789999*******************98875 PP == domain 2 score: 9.4 bits; conditional E-value: 0.001 RPN7 37 raledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksli...ekggdwerrnrlkvyeGlaalairkf 129 +a+++l+ y+ +g +++ +++ye+ ++ + g + + +++gi+ + + k +e ++ + +++gdw r k y ++++a ++f FUN_000335-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGEFPKAIECFEESLniaSEAGDWAGISRAKQYLRISYFALGDF 222 6899*********************************************99999999999888876511167999********************* PP RPN7 130 keAak 134 +A + FUN_000335-T1 223 LKAVE 227 99975 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 2 2.1e+03 14 33 .. 47 66 .. 44 67 .. 0.89 2 ? 2.5 0.0 0.3 3.2e+02 14 34 .] 87 107 .. 84 107 .. 0.92 3 ? 2.9 0.0 0.22 2.3e+02 13 28 .. 126 141 .. 123 147 .. 0.81 4 ? 4.9 0.0 0.051 54 14 34 .] 167 187 .. 164 187 .. 0.92 5 ? -1.6 0.0 6.3 6.7e+03 12 25 .. 882 895 .. 881 899 .. 0.82 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2 TPR_17 14 dayynLArlllnnGqleeAl 33 da+ L++++ ++ +A+ FUN_000335-T1 47 DAHLSLGIAYDSHSNFPKAI 66 8999********99999997 PP == domain 2 score: 2.5 bits; conditional E-value: 0.3 TPR_17 14 dayynLArlllnnGqleeAlq 34 day nL ++++ G++ +A++ FUN_000335-T1 87 DAYLNLLIAYKAIGDFPKAIE 107 89****************985 PP == domain 3 score: 2.9 bits; conditional E-value: 0.22 TPR_17 13 adayynLArlllnnGq 28 day nL+++++ G FUN_000335-T1 126 GDAYLNLGTAYEFHGG 141 59*********98876 PP == domain 4 score: 4.9 bits; conditional E-value: 0.051 TPR_17 14 dayynLArlllnnGqleeAlq 34 day nL+++++ G++ +A++ FUN_000335-T1 167 DAYLNLGIAHQSHGEFPKAIE 187 8*****************985 PP == domain 5 score: -1.6 bits; conditional E-value: 6.3 TPR_17 12 nadayynLArllln 25 n+++y n Ar++ FUN_000335-T1 882 NPKLYKNFARFYTA 895 8999******9975 PP >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 1.1e-05 0.012 15 81 .. 1172 1233 .. 1161 1234 .] 0.91 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.1e-05 Death 15 gkdWreLarklglseeeideiesenrdlrsqtyelLklWearegknatvgnLleaLrklgrrdaaek 81 g+ W+ +a++lgl+ ei+++ + r ++++ L +r + +v++L+++L ++g+ +a++ FUN_000335-T1 1172 GEGWKVVAERLGLNAKEIRYLDVRV---RNPCEAALSVVSQR--RCMNVDDLYDVLNECGMPVLADI 1233 799**********************...**************..7777************9887776 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.001 1.1 15 32 .. 60 77 .. 58 81 .. 0.89 2 ? -0.5 0.0 1.2 1.3e+03 17 31 .. 102 116 .. 99 120 .. 0.87 3 ? -1.9 0.0 3.2 3.4e+03 17 31 .. 142 156 .. 142 161 .. 0.81 4 ? -0.6 0.0 1.2 1.3e+03 16 30 .. 181 195 .. 177 198 .. 0.88 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.001 SHNi-TPR 15 enFeqAvkDlrkaLeLre 32 +nF+ A+k ++k+L++ + FUN_000335-T1 60 SNFPKAIKGYEKSLNIAR 77 8**************965 PP == domain 2 score: -0.5 bits; conditional E-value: 1.2 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F+ A++ ++k+L++ FUN_000335-T1 102 FPKAIECFEKSLDIA 116 999*********995 PP == domain 3 score: -1.9 bits; conditional E-value: 3.2 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F++ ++ ++k+L++ FUN_000335-T1 142 FSEGIESYEKSLDIA 156 7777899*****995 PP == domain 4 score: -0.6 bits; conditional E-value: 1.2 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++++L++ FUN_000335-T1 181 EFPKAIECFEESLNI 195 599***********8 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.016 17 16 115 .. 21 121 .. 17 126 .. 0.91 2 ? 10.6 0.0 0.00032 0.34 14 113 .. 99 199 .. 87 204 .. 0.91 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.016 TPR_MalT 16 eaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 + e +++ ++ L++ e +ar + a+l+lG a+ ++ +A + +++ +ar+a++ + a+l + + a G++ +A+e +++ l a FUN_000335-T1 21 SVREPMDHHEKHLNIAGEAHNPAReGDAHLSLGIAYDSHSNFPKAIKGYEKSLNIAREAGDRAREGDAYLNLLIAYKAIGDFPKAIECFEKSLDIA 116 56677888889999999999999999************************************999999999999********************** PP TPR_MalT 111 qeskl 115 +e++ FUN_000335-T1 117 REAGD 121 99865 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00032 TPR_MalT 14 qgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++++a+e ++ L++ +e a+ + a+l+lG+a+ g ++++ +++++ +arr ++ ++ a+l ++ ++ G++ +A+e +++ l FUN_000335-T1 99 IGDFPKAIECFEKSLDIAREAGDRAKeGDAYLNLGTAYEFHGGFSEGIESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGEFPKAIECFEESLN 194 58899999999999999998766665699******************************************************************9 PP TPR_MalT 109 laqes 113 a e+ FUN_000335-T1 195 IASEA 199 99876 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00016 0.17 4 26 .. 277 299 .. 273 310 .. 0.90 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00016 PduV-EutP 4 illiGkvgsGKttLtqalkgeel 26 i+liG+ sGKt+L+++l+g+++ FUN_000335-T1 277 IMLIGQDRSGKTSLKKSLQGLQF 299 9******************9876 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2.5 2.7e+03 29 38 .. 47 56 .. 47 60 .. 0.93 2 ? -1.1 0.1 2.1 2.2e+03 9 23 .. 61 75 .. 53 77 .. 0.86 3 ? 6.5 0.2 0.0088 9.4 3 38 .. 95 136 .. 95 140 .. 0.69 4 ? 3.0 0.2 0.11 1.2e+02 29 42 .] 167 180 .. 166 180 .. 0.91 5 ? 2.2 0.0 0.19 2.1e+02 8 23 .. 180 195 .. 178 199 .. 0.88 6 ? 0.8 0.1 0.55 5.9e+02 12 22 .. 256 266 .. 255 266 .. 0.88 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.5 TPR_11 29 eayynLGlay 38 +a++ LG ay FUN_000335-T1 47 DAHLSLGIAY 56 79*******9 PP == domain 2 score: -1.1 bits; conditional E-value: 2.1 TPR_11 9 kyeeAieaYkkAlkl 23 ++++Ai+ Y+k l++ FUN_000335-T1 61 NFPKAIKGYEKSLNI 75 6899*******9987 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0088 TPR_11 3 ayyeqGkyeeAieaYkkAlkl......dPdnaeayynLGlay 38 ay + G++++Aie+++k l++ + + +ay+nLG ay FUN_000335-T1 95 AYKAIGDFPKAIECFEKSLDIareagdRAKEGDAYLNLGTAY 136 68899************9998322222233446677777666 PP == domain 4 score: 3.0 bits; conditional E-value: 0.11 TPR_11 29 eayynLGlayykqG 42 +ay+nLG a++ G FUN_000335-T1 167 DAYLNLGIAHQSHG 180 79********9877 PP == domain 5 score: 2.2 bits; conditional E-value: 0.19 TPR_11 8 GkyeeAieaYkkAlkl 23 G++++Aie++++ l++ FUN_000335-T1 180 GEFPKAIECFEESLNI 195 9**********99987 PP == domain 6 score: 0.8 bits; conditional E-value: 0.55 TPR_11 12 eAieaYkkAlk 22 +A eaY+kAl+ FUN_000335-T1 256 KAREAYNKALR 266 799******96 PP >> G-alpha G-protein alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 0.00015 0.16 4 127 .. 258 409 .. 255 427 .. 0.59 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00015 G-alpha 4 skeidkqlkeekkkakkevklLllGageSGKsTilkqmkilhkkgfseeerkeyraviysnilrslktllealekleiel..............ee 85 ++ +k l+e k++ k+ + ++l+G+ SGK+++ k ++ l + ++ + + y ++ + +++ ++ + ++e e+ FUN_000335-T1 258 REAYNKALREGKTRVKR-IPIMLIGQDRSGKTSLKKSLQGLQFNPNEDGTVGIDVDPSYFKVTTEVWKTGKKDQAANKEEkapsfehhvarvvvEN 352 56678888888888888.********************9777444333333223333444444444444444444444445566666667777744 PP G-alpha 86 eenkerlkkllslesslk...............eeeefsselaeaikelwndpgiqe 127 +++e ++++++++s+ e++e+ +++ +++ +d++i + FUN_000335-T1 353 LKEQELPSEVKAVDESKDlessppmsteapiasETNEIAEDYRGPSSKIIHDQVIAS 409 444444444444444433444444665555555555555566666666666666655 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.071 76 38 66 .. 95 123 .. 88 124 .. 0.89 2 ? 5.4 0.0 0.025 27 32 65 .. 169 202 .. 165 210 .. 0.86 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.071 TPR_9 38 lyaqlgcleaAladLeaylalapdapdae 66 +y g++ +A++++e+ l++a +a d++ FUN_000335-T1 95 AYKAIGDFPKAIECFEKSLDIAREAGDRA 123 67778*****************9999985 PP == domain 2 score: 5.4 bits; conditional E-value: 0.025 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalapdapda 65 + + G++++ g + +A++++e l +a +a d FUN_000335-T1 169 YLNLGIAHQSHGEFPKAIECFEESLNIASEAGDW 202 6789*******************99999888775 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.95 1e+03 149 175 .. 60 86 .. 47 88 .. 0.82 2 ? 5.8 0.1 0.015 16 135 175 .. 87 126 .. 64 128 .. 0.87 3 ? 0.7 0.0 0.54 5.7e+02 135 175 .. 127 166 .. 126 168 .. 0.84 4 ? 0.1 0.0 0.83 8.9e+02 135 170 .. 167 201 .. 166 207 .. 0.91 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.95 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkeep 175 ++ +a+k +e++l +a+++g+r++e FUN_000335-T1 60 SNFPKAIKGYEKSLNIAREAGDRAREG 86 5688999***************99875 PP == domain 2 score: 5.8 bits; conditional E-value: 0.015 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ + + +a++++e++l +a+++g+r++e FUN_000335-T1 87 DAYLNLLIAYKAI-GDFPKAIECFEKSLDIAREAGDRAKEG 126 6888888888887.9999*******************9986 PP == domain 3 score: 0.7 bits; conditional E-value: 0.54 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ + e +++ ++ +e++l +a+++g+r +e FUN_000335-T1 127 DAYLNLGTAYEFH-GGFSEGIESYEKSLDIARRVGDRTSEG 166 6788887777777.788999****************98875 PP == domain 4 score: 0.1 bits; conditional E-value: 0.83 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgk 170 daYl+ +++ e+ +a++++e +l +a ++g+ FUN_000335-T1 167 DAYLNLGIAHQSH-GEFPKAIECFEESLNIASEAGD 201 79*****99*999.999**************99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1234 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 928 (0.036328); expected 510.9 (0.02) Passed bias filter: 723 (0.028303); expected 510.9 (0.02) Passed Vit filter: 86 (0.00336661); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 24 [number of targets reported over threshold] # CPU time: 0.50u 0.39s 00:00:00.89 Elapsed: 00:00:00.43 # Mc/sec: 11607.22 // Query: FUN_000336-T1 [L=603] Description: FUN_000336 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-169 551.0 11.8 2.8e-16 60.0 0.0 8.1 12 TPR_12 Tetratricopeptide repeat 1.1e-107 348.3 31.5 2.1e-08 34.1 0.1 12.7 12 TPR_1 Tetratricopeptide repeat 8.4e-69 222.3 6.1 0.00041 20.7 0.0 13.2 13 TPR_7 Tetratricopeptide repeat 5e-64 207.7 27.4 1.7e-05 25.0 0.0 12.8 12 TPR_2 Tetratricopeptide repeat 6e-64 207.3 32.9 6.5e-05 23.3 0.0 12.5 12 TPR_8 Tetratricopeptide repeat 1.4e-52 174.7 1.4 0.0028 18.1 0.0 12.5 12 TPR_10 Tetratricopeptide repeat 5.4e-28 96.9 49.6 0.31 11.3 0.0 19.5 23 TPR_11 TPR repeat 3.8e-27 92.7 0.0 3.9 8.5 0.0 13.9 13 TPR_17 Tetratricopeptide repeat 9.5e-27 94.0 1.1 6.4 7.5 0.0 12.2 12 DUF7018 Domain of unknown function (DUF7018) 1.3e-25 88.7 0.0 1.3 10.3 0.0 11.6 10 TPR_6 Tetratricopeptide repeat 1.8e-24 86.3 0.0 0.14 13.1 0.0 11.2 12 TPR_16 Tetratricopeptide repeat 2.9e-24 86.5 23.0 8.2e-10 39.1 1.8 4.8 5 SNAP Soluble NSF attachment protein, SNAP 1e-23 84.6 0.0 3.5e-05 23.7 0.0 5.2 7 TPR_MalT MalT-like TPR region 5e-17 62.8 2.5 1.8 8.6 0.0 9.5 8 ComR_TPR ComR tetratricopeptide 4.5e-15 55.9 0.0 0.83 10.2 0.0 9.1 9 TPR_9 Tetratricopeptide repeat 2.1e-14 53.8 26.6 0.94 10.1 0.1 11.5 12 MIT MIT (microtubule interacting and transport) 1.3e-13 51.5 0.1 12 6.5 0.0 10.2 12 Cerato-platanin Cerato-platanin 1.1e-12 48.6 14.3 2.5 8.3 0.0 11.0 12 DUF7380 Domain of unknown function (DUF7380) 1.2e-12 48.3 9.9 47 5.3 0.0 11.9 11 Sel1 Sel1 repeat 2e-12 47.5 4.2 5.7 7.3 0.0 10.9 12 TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, 4.8e-12 45.6 16.8 7.3 6.7 0.0 11.6 12 SHNi-TPR SHNi-TPR 3.3e-11 43.2 0.6 82 4.9 0.0 10.4 10 TPR_14 Tetratricopeptide repeat 6.9e-11 42.3 7.1 0.74 10.2 0.1 9.0 10 TP6A_N Type IIB DNA topoisomerase 1.6e-10 41.5 0.0 1.3 9.3 0.0 8.1 8 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR 1.8e-10 40.6 14.8 0.042 12.9 2.3 6.6 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.1e-09 39.1 1.3 1.8e+02 2.9 0.0 10.7 12 DUF7971 Family of unknown function (DUF7971) 1.5e-09 38.3 0.0 5.5 7.1 0.0 6.5 8 TPR_COPA_B COPA/B TPR domain 1.6e-09 38.2 13.3 4.6 7.9 0.0 9.4 9 ANAPC5 Anaphase-promoting complex subunit 5 5.5e-09 35.4 0.0 0.094 11.5 0.0 5.2 4 Cohesin_load Cohesin loading factor 5.6e-09 36.7 24.2 14 5.9 0.0 10.9 12 ARM_TT21_C Tetratricopeptide repeat protein 21 C-termi 2.9e-07 31.1 11.2 45 4.3 0.0 10.8 12 CoV_NSP8 Coronavirus replicase NSP8 1.3e-06 29.3 8.9 56 4.4 0.1 9.6 10 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth A 1.5e-06 28.5 12.6 3.9 7.6 0.1 8.2 7 RPN7 26S proteasome subunit RPN7 9.6e-06 26.2 1.4 57 4.2 0.0 6.8 10 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain 2.2e-05 24.2 0.4 9.7 5.6 0.0 5.7 6 Paf67 RNA polymerase I-associated factor PAF67 0.00089 19.7 2.1 5.6e+02 1.2 0.0 8.6 11 Vault Major Vault Protein repeat domain ------ inclusion threshold ------ 0.012 16.0 25.9 1.1e+02 3.4 0.0 10.5 11 ssDBP Phage single-stranded DNA-binding protein 0.038 14.6 12.5 57 4.4 0.1 7.8 10 MTES_1575 REase_MTES_1575 0.049 14.1 1.5 1.7e+02 2.6 0.0 6.2 5 Ferritin Ferritin-like domain 0.06 13.6 8.8 7.5 6.8 0.1 6.9 9 Clathrin Region in Clathrin and VPS 0.095 12.8 0.2 2.2e+02 1.7 0.0 5.4 6 Piezo_cap Piezo non-specific cation channel, cap doma 0.22 11.6 0.2 52 3.9 0.0 3.9 6 Foie-gras_1 Foie gras liver health family 1 9.3 7.1 14.0 70 4.3 0.0 7.6 8 RAG1 Recombination-activation protein 1 (RAG1) n Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.7 0.0 1e-12 6e-10 17 75 .. 18 74 .. 18 76 .. 0.96 2 ! 59.9 0.0 4.9e-19 2.9e-16 6 77 .] 87 156 .. 85 156 .. 0.95 3 ! 59.0 0.0 9.4e-19 5.6e-16 4 77 .] 125 196 .. 123 196 .. 0.96 4 ! 53.2 0.0 6e-17 3.5e-14 5 77 .] 166 236 .. 163 236 .. 0.95 5 ! 53.5 0.1 4.9e-17 2.9e-14 4 77 .] 205 276 .. 202 276 .. 0.94 6 ! 55.6 0.0 1e-17 6.2e-15 4 77 .] 245 316 .. 242 316 .. 0.95 7 ! 50.7 0.0 3.5e-16 2.1e-13 5 77 .] 286 356 .. 285 356 .. 0.94 8 ! 55.2 0.0 1.4e-17 8.6e-15 4 77 .] 325 396 .. 322 396 .. 0.95 9 ! 60.0 0.0 4.7e-19 2.8e-16 5 77 .] 366 436 .. 365 436 .. 0.96 10 ! 57.3 0.0 3.1e-18 1.9e-15 4 77 .] 405 476 .. 402 476 .. 0.96 11 ! 58.5 0.0 1.3e-18 8e-16 5 77 .] 446 516 .. 442 516 .. 0.96 12 ! 29.9 0.1 1.1e-09 6.7e-07 5 60 .. 486 539 .. 483 542 .. 0.94 Alignments for each domain: == domain 1 score: 39.7 bits; conditional E-value: 1e-12 TPR_12 17 grydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 g ++eAl+ +ek l +a+++ +d+ ++ a+ nLg++y + d+ +A+e++e++l+ia FUN_000336-T1 18 GSFQEALDKHEKQLKIATKA--GDRAGVGLAYLNLGIAYDSQSDFPKAIECYEKSLNIA 74 679*****************..99*********************************97 PP == domain 2 score: 59.9 bits; conditional E-value: 4.9e-19 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + nl+ ++ ++ +A+e++ek+l++a+++ +d++ + ta++nLg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 87 YFNLGVAYNSKSDFPKAIECYEKSLNIAREA--GDRHREGTAYCNLGVAYKSQSDFPKAIECYEKSLNIARE 156 669**************************99..66779*******************************986 PP == domain 3 score: 59.0 bits; conditional E-value: 9.4e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ta+ nl+ ++ + ++ +A+e++ek+l++a+++ +d++ + +++nLg +y + d+ +A+e +e++l+ia++ FUN_000336-T1 125 TAYCNLGVAYKSQSDFPKAIECYEKSLNIAREA--GDRDCEKDVYYNLGVAYDSQSDFPKAIESYEKSLNIARE 196 7999*****************************..89999*******************************986 PP == domain 4 score: 53.2 bits; conditional E-value: 6e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +++nl+ ++ + ++ +A+e +ek+l++a+++ +d++ + +a++ Lg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 166 VYYNLGVAYDSQSDFPKAIESYEKSLNIAREA--GDRHTEGRAYCSLGVAYNSQSDFPKAIECYEKSLNIARE 236 688***************************99..66779*******************************986 PP == domain 5 score: 53.5 bits; conditional E-value: 4.9e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+ ++ + ++ +A+e++ek+l++a+++ +d++ + +a++ Lg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 205 RAYCSLGVAYNSQSDFPKAIECYEKSLNIAREA--GDRHTEGRAYCSLGVAYNSQSDFLKAIECHEKSLNIARE 276 68888**************************99..66779*******************************986 PP == domain 6 score: 55.6 bits; conditional E-value: 1e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+ ++ + ++ +A+e++ek+l++a+++ +d++ + +++++Lg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 245 RAYCSLGVAYNSQSDFLKAIECHEKSLNIAREA--GDRDCEKIVYYDLGVAYDSQSDFPKAIECYEKSLNIARE 316 68888****************************..89999*******************************986 PP == domain 7 score: 50.7 bits; conditional E-value: 3.5e-16 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +++ l+ ++ + ++ +A+e++ek+l++a+++ G++h + +a++ Lg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 286 VYYDLGVAYDSQSDFPKAIECYEKSLNIAREA-GDQH-TEGRAYCSLGVAYNSQSDFPKAIECHEKSLNIARE 356 5778999**********************999.6666.99******************************986 PP == domain 8 score: 55.2 bits; conditional E-value: 1.4e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+ ++ + ++ +A+e++ek+l++a+++ +d++ + +++++Lg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 325 RAYCSLGVAYNSQSDFPKAIECHEKSLNIAREA--GDRDCEKIVYYDLGVAYNSQSDFPKAIECYEKSLNIARE 396 68888****************************..89999*******************************986 PP == domain 9 score: 60.0 bits; conditional E-value: 4.7e-19 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +++ l+ ++ + ++ +A+e++ek+l++a+++ +d+ + +a++nLg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSLNIAREA--GDRRREGRAYCNLGVTYKSQSDFPKAIECYEKSLNIARE 436 5789****************************..78889*******************************986 PP == domain 10 score: 57.3 bits; conditional E-value: 3.1e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+ ++ + ++ +A+e++ek+l++a+++ +d+ ++ ++++Lg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 405 RAYCNLGVTYKSQSDFPKAIECYEKSLNIAREA--GDRNGEKDVYYGLGVAYNSQSDFPKAIECYEKSLNIARE 476 7999*****************************..88999*******************************986 PP == domain 11 score: 58.5 bits; conditional E-value: 1.3e-18 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++++l+ ++ + ++ +A+e++ek+l++a+++ +d++ + +++nLg +y + d+ +A+e++e++l+ia++ FUN_000336-T1 446 VYYGLGVAYNSQSDFPKAIECYEKSLNIAREA--GDRDCEKDVYYNLGVAYDSQSDFPKAIECYEKSLNIARE 516 5789****************************..89999*******************************986 PP == domain 12 score: 29.9 bits; conditional E-value: 1.1e-09 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgd 60 +++nl+ ++ + ++ +A+e++ek+l++a+++ +d ++ +a + +++yl lg+ FUN_000336-T1 486 VYYNLGVAYDSQSDFPKAIECYEKSLNIAREA--GDQAAVRRASHYVAECYLGLGN 539 688****************************9..8899**************9998 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.1 7.3e-10 4.4e-07 3 30 .. 46 73 .. 44 75 .. 0.94 2 ! 30.1 0.0 6.6e-10 3.9e-07 2 31 .. 85 114 .. 85 116 .. 0.92 3 ! 34.1 0.1 3.6e-11 2.1e-08 3 31 .. 126 154 .. 125 156 .. 0.93 4 ! 30.4 0.0 5.1e-10 3e-07 2 31 .. 165 194 .. 165 196 .. 0.92 5 ! 31.1 0.0 3.1e-10 1.9e-07 2 31 .. 205 234 .. 204 236 .. 0.93 6 ! 22.6 0.1 1.6e-07 9.4e-05 2 31 .. 245 274 .. 244 276 .. 0.93 7 ! 28.8 0.0 1.6e-09 9.8e-07 3 31 .. 286 314 .. 285 316 .. 0.92 8 ! 25.7 0.0 1.6e-08 9.6e-06 2 31 .. 325 354 .. 324 356 .. 0.93 9 ! 29.1 0.1 1.4e-09 8e-07 3 31 .. 366 394 .. 365 396 .. 0.92 10 ! 33.9 0.0 4.2e-11 2.5e-08 2 31 .. 405 434 .. 404 436 .. 0.93 11 ! 31.1 0.1 3.1e-10 1.8e-07 2 31 .. 445 474 .. 445 476 .. 0.92 12 ! 33.9 0.1 4.2e-11 2.5e-08 2 31 .. 485 514 .. 485 516 .. 0.92 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 7.3e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlG ay ++ ++ +A+e+yek L + FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEKSLNI 73 9***********************9965 PP == domain 2 score: 30.1 bits; conditional E-value: 6.6e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlG+ay ++ ++ +A+e+yek L + FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEKSLNIA 114 58************************9775 PP == domain 3 score: 34.1 bits; conditional E-value: 3.6e-11 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a++nlG+ay ++ ++ +A+e+yek L + FUN_000336-T1 126 AYCNLGVAYKSQSDFPKAIECYEKSLNIA 154 9************************9775 PP == domain 4 score: 30.4 bits; conditional E-value: 5.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++ynlG+ay ++ ++ +A+e yek L + FUN_000336-T1 165 DVYYNLGVAYDSQSDFPKAIESYEKSLNIA 194 68************************9775 PP == domain 5 score: 31.1 bits; conditional E-value: 3.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++ lG+ay ++ ++ +A+e+yek L + FUN_000336-T1 205 RAYCSLGVAYNSQSDFPKAIECYEKSLNIA 234 79************************9775 PP == domain 6 score: 22.6 bits; conditional E-value: 1.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++ lG+ay ++ ++ +A+e+ ek L + FUN_000336-T1 245 RAYCSLGVAYNSQSDFLKAIECHEKSLNIA 274 79***********************99775 PP == domain 7 score: 28.8 bits; conditional E-value: 1.6e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++y lG+ay ++ ++ +A+e+yek L + FUN_000336-T1 286 VYYDLGVAYDSQSDFPKAIECYEKSLNIA 314 79***********************9775 PP == domain 8 score: 25.7 bits; conditional E-value: 1.6e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++ lG+ay ++ ++ +A+e+ ek L + FUN_000336-T1 325 RAYCSLGVAYNSQSDFPKAIECHEKSLNIA 354 79***********************99775 PP == domain 9 score: 29.1 bits; conditional E-value: 1.4e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++y lG+ay ++ ++ +A+e+yek L + FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSLNIA 394 79***********************9775 PP == domain 10 score: 33.9 bits; conditional E-value: 4.2e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG++y ++ ++ +A+e+yek L + FUN_000336-T1 405 RAYCNLGVTYKSQSDFPKAIECYEKSLNIA 434 79************************9775 PP == domain 11 score: 31.1 bits; conditional E-value: 3.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++y+lG+ay ++ ++ +A+e+yek L + FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIECYEKSLNIA 474 68************************9775 PP == domain 12 score: 33.9 bits; conditional E-value: 4.2e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++ynlG+ay ++ ++ +A+e+yek L + FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEKSLNIA 514 68************************9775 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.021 12 15 36 .] 20 41 .. 18 41 .. 0.91 2 ! 20.0 0.0 1.1e-06 0.00068 1 35 [. 46 80 .. 46 81 .. 0.95 3 ! 16.8 0.0 1.3e-05 0.0075 2 35 .. 87 120 .. 86 120 .. 0.95 4 ! 19.3 0.0 2e-06 0.0012 4 35 .. 129 160 .. 126 161 .. 0.95 5 ! 20.5 0.0 7.9e-07 0.00047 2 35 .. 167 200 .. 166 200 .. 0.95 6 ! 15.0 0.0 4.8e-05 0.029 4 35 .. 209 240 .. 206 240 .. 0.95 7 ! 9.9 0.0 0.002 1.2 4 35 .. 249 280 .. 246 281 .. 0.94 8 ! 16.7 0.0 1.3e-05 0.0076 3 34 .. 288 319 .. 286 320 .. 0.92 9 ! 13.9 0.0 0.00011 0.064 4 35 .. 329 360 .. 326 361 .. 0.95 10 ! 15.7 0.0 2.9e-05 0.017 3 35 .. 368 400 .. 366 401 .. 0.93 11 ! 18.3 0.0 4e-06 0.0024 4 35 .. 409 440 .. 406 440 .. 0.95 12 ! 16.2 0.0 1.9e-05 0.011 3 35 .. 448 480 .. 446 481 .. 0.94 13 ! 20.7 0.0 6.9e-07 0.00041 2 35 .. 487 520 .. 486 521 .. 0.94 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.021 TPR_7 15 ydeAirlyerlLalakdpedre 36 ++eA++ +e++L +a + +dr+ FUN_000336-T1 20 FQEALDKHEKQLKIATKAGDRA 41 89**************999985 PP == domain 2 score: 20.0 bits; conditional E-value: 1.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y ++ d+ +Ai++ye+ L +a + +dr FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEKSLNIAGEAGDR 80 789**************************999987 PP == domain 3 score: 16.8 bits; conditional E-value: 1.3e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000336-T1 87 YFNLGVAYNSKSDFPKAIECYEKSLNIAREAGDR 120 579**************************99997 PP == domain 4 score: 19.3 bits; conditional E-value: 2e-06 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedr 35 +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000336-T1 129 NLGVAYKSQSDFPKAIECYEKSLNIAREAGDR 160 8***************************9998 PP == domain 5 score: 20.5 bits; conditional E-value: 7.9e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L+ +y ++ d+ +Ai+ ye+ L +a++ +dr FUN_000336-T1 167 YYNLGVAYDSQSDFPKAIESYEKSLNIAREAGDR 200 68***************************99997 PP == domain 6 score: 15.0 bits; conditional E-value: 4.8e-05 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedr 35 +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000336-T1 209 SLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 240 69*************************99997 PP == domain 7 score: 9.9 bits; conditional E-value: 0.002 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedr 35 +L+ +y ++ d+ +Ai+++e+ L +a++ +dr FUN_000336-T1 249 SLGVAYNSQSDFLKAIECHEKSLNIAREAGDR 280 699*************************9998 PP == domain 8 score: 16.7 bits; conditional E-value: 1.3e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdped 34 + L+ +y ++ d+ +Ai++ye+ L +a++ +d FUN_000336-T1 288 YDLGVAYDSQSDFPKAIECYEKSLNIAREAGD 319 569************************99887 PP == domain 9 score: 13.9 bits; conditional E-value: 0.00011 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedr 35 +L+ +y ++ d+ +Ai+++e+ L +a++ +dr FUN_000336-T1 329 SLGVAYNSQSDFPKAIECHEKSLNIAREAGDR 360 69**************************9998 PP == domain 10 score: 15.7 bits; conditional E-value: 2.9e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 + L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000336-T1 368 YDLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 400 569**************************9998 PP == domain 11 score: 18.3 bits; conditional E-value: 4e-06 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedr 35 +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000336-T1 409 NLGVTYKSQSDFPKAIECYEKSLNIAREAGDR 440 8**************************99997 PP == domain 12 score: 16.2 bits; conditional E-value: 1.9e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 + L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000336-T1 448 YGLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 480 689**************************9998 PP == domain 13 score: 20.7 bits; conditional E-value: 6.9e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L+ +y ++ d+ +Ai++ye+ L +a++ +d+ FUN_000336-T1 487 YYNLGVAYDSQSDFPKAIECYEKSLNIAREAGDQ 520 68***************************99997 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.1 2.7e-07 0.00016 3 31 .. 46 74 .. 44 77 .. 0.92 2 ! 17.8 0.0 6e-06 0.0036 2 32 .. 85 115 .. 84 117 .. 0.92 3 ! 23.7 0.0 7.5e-08 4.5e-05 3 32 .. 126 155 .. 124 157 .. 0.93 4 ! 22.3 0.0 2.1e-07 0.00013 2 32 .. 165 195 .. 164 197 .. 0.93 5 ! 15.9 0.0 2.6e-05 0.015 2 32 .. 205 235 .. 204 237 .. 0.92 6 ? 4.4 0.1 0.12 71 2 31 .. 245 274 .. 244 277 .. 0.90 7 ! 22.0 0.0 2.7e-07 0.00016 3 32 .. 286 315 .. 285 317 .. 0.93 8 ? 6.3 0.0 0.03 18 2 31 .. 325 354 .. 324 357 .. 0.90 9 ! 17.0 0.0 1.1e-05 0.0067 3 32 .. 366 395 .. 365 397 .. 0.93 10 ! 22.7 0.0 1.6e-07 9.8e-05 2 32 .. 405 435 .. 404 437 .. 0.93 11 ! 17.6 0.0 6.8e-06 0.0041 2 32 .. 445 475 .. 444 477 .. 0.92 12 ! 25.0 0.0 2.9e-08 1.7e-05 2 32 .. 485 515 .. 484 517 .. 0.93 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 2.7e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG ay + d+ +A+e+yek+l ++ FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEKSLNIA 74 89************************986 PP == domain 2 score: 17.8 bits; conditional E-value: 6e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG ay + d+ +A+e+yek+l ++ FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEKSLNIAR 115 58*************************9875 PP == domain 3 score: 23.7 bits; conditional E-value: 7.5e-08 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a++nlG ay + d+ +A+e+yek+l ++ FUN_000336-T1 126 AYCNLGVAYKSQSDFPKAIECYEKSLNIAR 155 8*************************9875 PP == domain 4 score: 22.3 bits; conditional E-value: 2.1e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +++ynlG ay + d+ +A+e yek+l ++ FUN_000336-T1 165 DVYYNLGVAYDSQSDFPKAIESYEKSLNIAR 195 58*************************9875 PP == domain 5 score: 15.9 bits; conditional E-value: 2.6e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++ lG ay + d+ +A+e+yek+l ++ FUN_000336-T1 205 RAYCSLGVAYNSQSDFPKAIECYEKSLNIAR 235 6899***********************9875 PP == domain 6 score: 4.4 bits; conditional E-value: 0.12 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++ lG ay + d+ +A+e+ ek+l ++ FUN_000336-T1 245 RAYCSLGVAYNSQSDFLKAIECHEKSLNIA 274 68999*****************99999887 PP == domain 7 score: 22.0 bits; conditional E-value: 2.7e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 ++y lG ay + d+ +A+e+yek+l ++ FUN_000336-T1 286 VYYDLGVAYDSQSDFPKAIECYEKSLNIAR 315 69************************9875 PP == domain 8 score: 6.3 bits; conditional E-value: 0.03 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++ lG ay + d+ +A+e+ ek+l ++ FUN_000336-T1 325 RAYCSLGVAYNSQSDFPKAIECHEKSLNIA 354 6899******************99999887 PP == domain 9 score: 17.0 bits; conditional E-value: 1.1e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 ++y lG ay + d+ +A+e+yek+l ++ FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSLNIAR 395 69************************9875 PP == domain 10 score: 22.7 bits; conditional E-value: 1.6e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG y + d+ +A+e+yek+l ++ FUN_000336-T1 405 RAYCNLGVTYKSQSDFPKAIECYEKSLNIAR 435 69*************************9875 PP == domain 11 score: 17.6 bits; conditional E-value: 6.8e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +++y lG ay + d+ +A+e+yek+l ++ FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIECYEKSLNIAR 475 589************************9875 PP == domain 12 score: 25.0 bits; conditional E-value: 2.9e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +++ynlG ay + d+ +A+e+yek+l ++ FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEKSLNIAR 515 58*************************9875 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.1 1.3e-05 0.008 3 31 .. 46 74 .. 45 76 .. 0.95 2 ! 20.0 0.0 1.2e-06 0.00074 2 32 .. 85 115 .. 84 116 .. 0.94 3 ! 22.3 0.1 2.3e-07 0.00014 3 32 .. 126 155 .. 124 156 .. 0.94 4 ! 20.6 0.1 7.6e-07 0.00045 2 32 .. 165 195 .. 164 196 .. 0.94 5 ! 18.8 0.1 3e-06 0.0018 2 32 .. 205 235 .. 204 236 .. 0.95 6 ! 13.2 0.1 0.00018 0.11 2 32 .. 245 275 .. 244 276 .. 0.95 7 ! 18.2 0.1 4.5e-06 0.0027 3 32 .. 286 315 .. 285 316 .. 0.95 8 ! 11.2 0.0 0.00082 0.49 2 32 .. 325 355 .. 324 356 .. 0.95 9 ! 17.1 0.1 1e-05 0.0062 3 32 .. 366 395 .. 365 396 .. 0.95 10 ! 23.3 0.0 1.1e-07 6.5e-05 2 32 .. 405 435 .. 404 436 .. 0.95 11 ! 17.7 0.1 6.9e-06 0.0041 2 32 .. 445 475 .. 444 476 .. 0.94 12 ! 22.2 0.1 2.4e-07 0.00014 2 32 .. 485 515 .. 484 516 .. 0.94 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.3e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay+nlG +y ++ d+ +A+e+yek+l ++ FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEKSLNIA 74 8*************************986 PP == domain 2 score: 20.0 bits; conditional E-value: 1.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++y+nlG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEKSLNIAR 115 58*************************9987 PP == domain 3 score: 22.3 bits; conditional E-value: 2.3e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay+nlG +y+++ d+ +A+e+yek+l +++ FUN_000336-T1 126 AYCNLGVAYKSQSDFPKAIECYEKSLNIAR 155 9*************************9987 PP == domain 4 score: 20.6 bits; conditional E-value: 7.6e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++yynlG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 165 DVYYNLGVAYDSQSDFPKAIESYEKSLNIAR 195 58*************************9987 PP == domain 5 score: 18.8 bits; conditional E-value: 3e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ lG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 205 RAYCSLGVAYNSQSDFPKAIECYEKSLNIAR 235 89*************************9987 PP == domain 6 score: 13.2 bits; conditional E-value: 0.00018 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ lG +y ++ d+ +A+e+ ek+l +++ FUN_000336-T1 245 RAYCSLGVAYNSQSDFLKAIECHEKSLNIAR 275 89*************************9986 PP == domain 7 score: 18.2 bits; conditional E-value: 4.5e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +yy lG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 286 VYYDLGVAYDSQSDFPKAIECYEKSLNIAR 315 6*************************9987 PP == domain 8 score: 11.2 bits; conditional E-value: 0.00082 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ lG +y ++ d+ +A+e+ ek+l +++ FUN_000336-T1 325 RAYCSLGVAYNSQSDFPKAIECHEKSLNIAR 355 89*************************9986 PP == domain 9 score: 17.1 bits; conditional E-value: 1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +yy lG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSLNIAR 395 6*************************9987 PP == domain 10 score: 23.3 bits; conditional E-value: 1.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y+++ d+ +A+e+yek+l +++ FUN_000336-T1 405 RAYCNLGVTYKSQSDFPKAIECYEKSLNIAR 435 89*************************9987 PP == domain 11 score: 17.7 bits; conditional E-value: 6.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++yy lG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIECYEKSLNIAR 475 58*************************9987 PP == domain 12 score: 22.2 bits; conditional E-value: 2.4e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++yynlG +y ++ d+ +A+e+yek+l +++ FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEKSLNIAR 515 58*************************9987 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 0.00027 0.16 4 32 .. 46 74 .. 43 77 .. 0.92 2 ! 10.3 0.0 0.0013 0.78 7 35 .. 89 117 .. 87 122 .. 0.95 3 ! 18.1 0.0 4.6e-06 0.0028 3 35 .. 125 157 .. 124 157 .. 0.95 4 ! 12.8 0.0 0.00021 0.13 5 35 .. 167 197 .. 165 201 .. 0.93 5 ! 14.0 0.0 8.9e-05 0.053 4 35 .. 206 237 .. 204 241 .. 0.93 6 ! 9.9 0.0 0.0018 1.1 4 35 .. 246 277 .. 244 277 .. 0.93 7 ! 11.3 0.0 0.00063 0.38 5 35 .. 287 317 .. 286 321 .. 0.92 8 ! 13.2 0.0 0.00016 0.098 4 35 .. 326 357 .. 324 357 .. 0.94 9 ! 12.4 0.0 0.00029 0.17 5 35 .. 367 397 .. 366 397 .. 0.93 10 ! 17.5 0.0 7.5e-06 0.0044 4 35 .. 406 437 .. 404 437 .. 0.94 11 ! 11.4 0.0 0.0006 0.36 7 35 .. 449 477 .. 445 477 .. 0.92 12 ! 14.4 0.0 6.8e-05 0.04 5 35 .. 487 517 .. 485 517 .. 0.94 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00027 TPR_10 4 slnnLanalraqgryeeAeelleealair 32 ++ nL+ a+ +q ++ A e +e++l i+ FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEKSLNIA 74 799***********************986 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0013 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++a+ + ++ A e +e++l i++++ FUN_000336-T1 89 NLGVAYNSKSDFPKAIECYEKSLNIAREA 117 9************************9875 PP == domain 3 score: 18.1 bits; conditional E-value: 4.6e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL++a+ +q ++ A e +e++l i++++ FUN_000336-T1 125 TAYCNLGVAYKSQSDFPKAIECYEKSLNIAREA 157 799**************************9985 PP == domain 4 score: 12.8 bits; conditional E-value: 0.00021 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + nL++a+ +q ++ A e +e++l i++++ FUN_000336-T1 167 YYNLGVAYDSQSDFPKAIESYEKSLNIAREA 197 78*************************9985 PP == domain 5 score: 14.0 bits; conditional E-value: 8.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L++a+ +q ++ A e +e++l i++++ FUN_000336-T1 206 AYCSLGVAYNSQSDFPKAIECYEKSLNIAREA 237 7899************************9985 PP == domain 6 score: 9.9 bits; conditional E-value: 0.0018 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L++a+ +q ++ A e +e++l i++++ FUN_000336-T1 246 AYCSLGVAYNSQSDFLKAIECHEKSLNIAREA 277 7899************************9985 PP == domain 7 score: 11.3 bits; conditional E-value: 0.00063 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + +L++a+ +q ++ A e +e++l i++++ FUN_000336-T1 287 YYDLGVAYDSQSDFPKAIECYEKSLNIAREA 317 568************************9985 PP == domain 8 score: 13.2 bits; conditional E-value: 0.00016 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L++a+ +q ++ A e +e++l i++++ FUN_000336-T1 326 AYCSLGVAYNSQSDFPKAIECHEKSLNIAREA 357 7899************************9985 PP == domain 9 score: 12.4 bits; conditional E-value: 0.00029 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + +L++a+ +q ++ A e +e++l i++++ FUN_000336-T1 367 YYDLGVAYNSQSDFPKAIECYEKSLNIAREA 397 568************************9985 PP == domain 10 score: 17.5 bits; conditional E-value: 7.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL++++ +q ++ A e +e++l i++++ FUN_000336-T1 406 AYCNLGVTYKSQSDFPKAIECYEKSLNIAREA 437 899*************************9985 PP == domain 11 score: 11.4 bits; conditional E-value: 0.0006 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 L++a+ +q ++ A e +e++l i++++ FUN_000336-T1 449 GLGVAYNSQSDFPKAIECYEKSLNIAREA 477 69***********************9985 PP == domain 12 score: 14.4 bits; conditional E-value: 6.8e-05 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + nL++a+ +q ++ A e +e++l i++++ FUN_000336-T1 487 YYNLGVAYDSQSDFPKAIECYEKSLNIAREA 517 78*************************9985 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.2 0.54 3.2e+02 30 38 .. 46 54 .. 45 58 .. 0.87 2 ! 7.6 0.0 0.0072 4.2 4 23 .. 54 73 .. 51 74 .. 0.86 3 ? 3.5 0.1 0.14 83 29 38 .. 85 94 .. 85 97 .. 0.90 4 ! 10.4 0.0 0.00094 0.56 3 23 .. 93 113 .. 91 117 .. 0.90 5 ? 6.1 0.1 0.021 12 29 41 .. 125 137 .. 124 138 .. 0.89 6 ! 11.0 0.0 0.00063 0.38 3 23 .. 133 153 .. 131 157 .. 0.90 7 ? 5.5 0.6 0.033 20 29 38 .. 165 174 .. 164 178 .. 0.88 8 ? 6.4 0.1 0.017 9.9 6 23 .. 176 193 .. 173 197 .. 0.87 9 ? 1.7 0.0 0.5 2.9e+02 30 39 .. 206 215 .. 205 218 .. 0.84 10 ! 11.3 0.0 0.00052 0.31 3 23 .. 213 233 .. 211 237 .. 0.90 11 ? 2.2 0.0 0.35 2.1e+02 30 39 .. 246 255 .. 240 273 .. 0.81 12 ? 1.4 0.2 0.61 3.6e+02 30 38 .. 286 294 .. 285 298 .. 0.86 13 ! 8.1 0.1 0.0052 3.1 3 23 .. 293 313 .. 291 317 .. 0.86 14 ? 1.8 0.0 0.48 2.8e+02 30 39 .. 326 335 .. 324 338 .. 0.84 15 ? 3.7 0.0 0.12 72 3 23 .. 333 353 .. 331 356 .. 0.88 16 ? 1.2 0.1 0.71 4.2e+02 30 38 .. 366 374 .. 366 377 .. 0.85 17 ! 11.3 0.0 0.00052 0.31 3 23 .. 373 393 .. 371 397 .. 0.90 18 ? 4.2 0.1 0.085 51 30 41 .. 406 417 .. 404 418 .. 0.88 19 ! 9.6 0.0 0.0017 1 3 23 .. 413 433 .. 411 437 .. 0.89 20 ? 3.5 0.3 0.13 79 29 39 .. 445 455 .. 444 458 .. 0.86 21 ! 11.3 0.0 0.00052 0.31 3 23 .. 453 473 .. 451 477 .. 0.90 22 ? 5.5 0.6 0.034 20 29 38 .. 485 494 .. 484 498 .. 0.88 23 ? 6.8 0.0 0.012 7.4 6 23 .. 496 513 .. 494 516 .. 0.88 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.54 TPR_11 30 ayynLGlay 38 ay+nLG ay FUN_000336-T1 46 AYLNLGIAY 54 8*******9 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0072 TPR_11 4 yyeqGkyeeAieaYkkAlkl 23 y +q ++++Aie+Y+k l++ FUN_000336-T1 54 YDSQSDFPKAIECYEKSLNI 73 668999**********9987 PP == domain 3 score: 3.5 bits; conditional E-value: 0.14 TPR_11 29 eayynLGlay 38 ++y+nLG+ay FUN_000336-T1 85 DVYFNLGVAY 94 78*******9 PP == domain 4 score: 10.4 bits; conditional E-value: 0.00094 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay ++ ++++Aie+Y+k l++ FUN_000336-T1 93 AYNSKSDFPKAIECYEKSLNI 113 899**************9987 PP == domain 5 score: 6.1 bits; conditional E-value: 0.021 TPR_11 29 eayynLGlayykq 41 +ay+nLG+ay q FUN_000336-T1 125 TAYCNLGVAYKSQ 137 59********876 PP == domain 6 score: 11.0 bits; conditional E-value: 0.00063 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+Y+k l++ FUN_000336-T1 133 AYKSQSDFPKAIECYEKSLNI 153 89***************9987 PP == domain 7 score: 5.5 bits; conditional E-value: 0.033 TPR_11 29 eayynLGlay 38 ++yynLG+ay FUN_000336-T1 165 DVYYNLGVAY 174 79*******9 PP == domain 8 score: 6.4 bits; conditional E-value: 0.017 TPR_11 6 eqGkyeeAieaYkkAlkl 23 +q ++++Aie+Y+k l++ FUN_000336-T1 176 SQSDFPKAIESYEKSLNI 193 7899**********9987 PP == domain 9 score: 1.7 bits; conditional E-value: 0.5 TPR_11 30 ayynLGlayy 39 ay+ LG+ay FUN_000336-T1 206 AYCSLGVAYN 215 9*******95 PP == domain 10 score: 11.3 bits; conditional E-value: 0.00052 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+Y+k l++ FUN_000336-T1 213 AYNSQSDFPKAIECYEKSLNI 233 89***************9987 PP == domain 11 score: 2.2 bits; conditional E-value: 0.35 TPR_11 30 ayynLGlayy 39 ay+ LG+ay FUN_000336-T1 246 AYCSLGVAYN 255 7888888884 PP == domain 12 score: 1.4 bits; conditional E-value: 0.61 TPR_11 30 ayynLGlay 38 +yy LG+ay FUN_000336-T1 286 VYYDLGVAY 294 7*******9 PP == domain 13 score: 8.1 bits; conditional E-value: 0.0052 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+Y+k l++ FUN_000336-T1 293 AYDSQSDFPKAIECYEKSLNI 313 5668999**********9987 PP == domain 14 score: 1.8 bits; conditional E-value: 0.48 TPR_11 30 ayynLGlayy 39 ay+ LG+ay FUN_000336-T1 326 AYCSLGVAYN 335 9*******95 PP == domain 15 score: 3.7 bits; conditional E-value: 0.12 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+ +k l++ FUN_000336-T1 333 AYNSQSDFPKAIECHEKSLNI 353 89************9998876 PP == domain 16 score: 1.2 bits; conditional E-value: 0.71 TPR_11 30 ayynLGlay 38 +yy LG+ay FUN_000336-T1 366 VYYDLGVAY 374 6*******9 PP == domain 17 score: 11.3 bits; conditional E-value: 0.00052 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+Y+k l++ FUN_000336-T1 373 AYNSQSDFPKAIECYEKSLNI 393 89***************9987 PP == domain 18 score: 4.2 bits; conditional E-value: 0.085 TPR_11 30 ayynLGlayykq 41 ay+nLG++y q FUN_000336-T1 406 AYCNLGVTYKSQ 417 9********876 PP == domain 19 score: 9.6 bits; conditional E-value: 0.0017 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 y +q ++++Aie+Y+k l++ FUN_000336-T1 413 TYKSQSDFPKAIECYEKSLNI 433 5899*************9987 PP == domain 20 score: 3.5 bits; conditional E-value: 0.13 TPR_11 29 eayynLGlayy 39 ++yy+LG+ay FUN_000336-T1 445 DVYYGLGVAYN 455 79*******95 PP == domain 21 score: 11.3 bits; conditional E-value: 0.00052 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+Y+k l++ FUN_000336-T1 453 AYNSQSDFPKAIECYEKSLNI 473 89***************9987 PP == domain 22 score: 5.5 bits; conditional E-value: 0.034 TPR_11 29 eayynLGlay 38 ++yynLG+ay FUN_000336-T1 485 DVYYNLGVAY 494 79*******9 PP == domain 23 score: 6.8 bits; conditional E-value: 0.012 TPR_11 6 eqGkyeeAieaYkkAlkl 23 +q ++++Aie+Y+k l++ FUN_000336-T1 496 SQSDFPKAIECYEKSLNI 513 57899*********9987 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.042 25 15 34 .] 46 65 .. 44 65 .. 0.92 2 ? 6.6 0.0 0.027 16 14 34 .] 85 105 .. 84 105 .. 0.92 3 ? 7.0 0.0 0.019 11 15 34 .] 126 145 .. 123 145 .. 0.93 4 ! 8.5 0.0 0.0065 3.9 14 34 .] 165 185 .. 163 185 .. 0.93 5 ? 4.5 0.0 0.12 70 14 34 .] 205 225 .. 201 225 .. 0.90 6 ? 3.6 0.0 0.24 1.4e+02 14 34 .] 245 265 .. 241 265 .. 0.89 7 ? 0.2 0.0 3 1.8e+03 2 10 .. 260 268 .. 259 271 .. 0.85 8 ? 4.8 0.0 0.099 59 15 34 .] 286 305 .. 284 305 .. 0.92 9 ? 4.7 0.0 0.1 62 14 34 .] 325 345 .. 319 345 .. 0.89 10 ? 4.7 0.0 0.11 63 15 34 .] 366 385 .. 364 385 .. 0.92 11 ! 8.3 0.0 0.0072 4.3 14 34 .] 405 425 .. 402 425 .. 0.92 12 ? 4.3 0.0 0.14 83 14 34 .] 445 465 .. 442 465 .. 0.92 13 ! 8.5 0.0 0.0065 3.9 14 34 .] 485 505 .. 483 505 .. 0.93 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.042 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL++++ + ++ +A++ FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIE 65 8****************985 PP == domain 2 score: 6.6 bits; conditional E-value: 0.027 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL++++ + ++ +A++ FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIE 105 78**************99985 PP == domain 3 score: 7.0 bits; conditional E-value: 0.019 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay+nL+++++ + ++ +A++ FUN_000336-T1 126 AYCNLGVAYKSQSDFPKAIE 145 8****************985 PP == domain 4 score: 8.5 bits; conditional E-value: 0.0065 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+yynL++++ + ++ +A++ FUN_000336-T1 165 DVYYNLGVAYDSQSDFPKAIE 185 79****************985 PP == domain 5 score: 4.5 bits; conditional E-value: 0.12 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+ L++++ + ++ +A++ FUN_000336-T1 205 RAYCSLGVAYNSQSDFPKAIE 225 69***************9985 PP == domain 6 score: 3.6 bits; conditional E-value: 0.24 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+ L++++ + ++ +A++ FUN_000336-T1 245 RAYCSLGVAYNSQSDFLKAIE 265 69*************999985 PP == domain 7 score: 0.2 bits; conditional E-value: 3 TPR_17 2 ylkaleldP 10 +lka+e++ FUN_000336-T1 260 FLKAIECHE 268 89*****86 PP == domain 8 score: 4.8 bits; conditional E-value: 0.099 TPR_17 15 ayynLArlllnnGqleeAlq 34 +yy+L++++ + ++ +A++ FUN_000336-T1 286 VYYDLGVAYDSQSDFPKAIE 305 6****************985 PP == domain 9 score: 4.7 bits; conditional E-value: 0.1 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+ L++++ + ++ +A++ FUN_000336-T1 325 RAYCSLGVAYNSQSDFPKAIE 345 79***************9985 PP == domain 10 score: 4.7 bits; conditional E-value: 0.11 TPR_17 15 ayynLArlllnnGqleeAlq 34 +yy+L++++ + ++ +A++ FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIE 385 6***************9985 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0072 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+nL+++++ + ++ +A++ FUN_000336-T1 405 RAYCNLGVTYKSQSDFPKAIE 425 59****************985 PP == domain 12 score: 4.3 bits; conditional E-value: 0.14 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+yy L++++ + ++ +A++ FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIE 465 79***************9985 PP == domain 13 score: 8.5 bits; conditional E-value: 0.0065 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+yynL++++ + ++ +A++ FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIE 505 79****************985 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.024 14 67 92 .. 55 80 .. 52 89 .. 0.85 2 ? 4.2 0.0 0.12 71 67 92 .. 95 120 .. 92 126 .. 0.85 3 ? 6.7 0.0 0.019 12 68 92 .. 136 160 .. 132 170 .. 0.84 4 ? 7.5 0.0 0.011 6.4 67 92 .. 175 200 .. 171 208 .. 0.89 5 ? 6.9 0.0 0.017 9.8 67 92 .. 215 240 .. 212 248 .. 0.88 6 ? 5.5 0.0 0.046 27 67 95 .. 255 283 .. 252 290 .. 0.86 7 ? 7.0 0.0 0.016 9.2 67 91 .. 295 319 .. 288 326 .. 0.88 8 ? 4.4 0.0 0.098 58 67 95 .. 335 363 .. 332 369 .. 0.86 9 ? 6.9 0.0 0.017 10 67 92 .. 375 400 .. 368 406 .. 0.88 10 ? 6.8 0.0 0.019 11 68 93 .. 416 441 .. 412 448 .. 0.84 11 ? 7.2 0.0 0.013 7.8 67 92 .. 455 480 .. 453 490 .. 0.85 12 ? 6.9 0.0 0.017 9.9 67 91 .. 495 519 .. 491 532 .. 0.88 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.024 DUF7018 67 dvqkllekaidhyekslklieeavek 92 d q ++ kai+ yeksl+++ ea ++ FUN_000336-T1 55 DSQSDFPKAIECYEKSLNIAGEAGDR 80 78*****************9998666 PP == domain 2 score: 4.2 bits; conditional E-value: 0.12 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + + ++ kai+ yeksl++++ea ++ FUN_000336-T1 95 NSKSDFPKAIECYEKSLNIAREAGDR 120 56789***************998665 PP == domain 3 score: 6.7 bits; conditional E-value: 0.019 DUF7018 68 vqkllekaidhyekslklieeavek 92 q ++ kai+ yeksl++++ea ++ FUN_000336-T1 136 SQSDFPKAIECYEKSLNIAREAGDR 160 699*****************99776 PP == domain 4 score: 7.5 bits; conditional E-value: 0.011 DUF7018 67 dvqkllekaidhyekslklieeavek 92 d q ++ kai+ yeksl++++ea ++ FUN_000336-T1 175 DSQSDFPKAIESYEKSLNIAREAGDR 200 78******************999766 PP == domain 5 score: 6.9 bits; conditional E-value: 0.017 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000336-T1 215 NSQSDFPKAIECYEKSLNIAREAGDR 240 689*****************999766 PP == domain 6 score: 5.5 bits; conditional E-value: 0.046 DUF7018 67 dvqkllekaidhyekslklieeavekkdk 95 + q ++ kai+ +eksl++++ea ++ + FUN_000336-T1 255 NSQSDFLKAIECHEKSLNIAREAGDRDCE 283 68*******************99877655 PP == domain 7 score: 7.0 bits; conditional E-value: 0.016 DUF7018 67 dvqkllekaidhyekslklieeave 91 d q ++ kai+ yeksl++++ea + FUN_000336-T1 295 DSQSDFPKAIECYEKSLNIAREAGD 319 78*****************999865 PP == domain 8 score: 4.4 bits; conditional E-value: 0.098 DUF7018 67 dvqkllekaidhyekslklieeavekkdk 95 + q ++ kai+ +eksl++++ea ++ + FUN_000336-T1 335 NSQSDFPKAIECHEKSLNIAREAGDRDCE 363 689******************99877655 PP == domain 9 score: 6.9 bits; conditional E-value: 0.017 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000336-T1 375 NSQSDFPKAIECYEKSLNIAREAGDR 400 689*****************998665 PP == domain 10 score: 6.8 bits; conditional E-value: 0.019 DUF7018 68 vqkllekaidhyekslklieeavekk 93 q ++ kai+ yeksl++++ea +++ FUN_000336-T1 416 SQSDFPKAIECYEKSLNIAREAGDRN 441 699*****************997774 PP == domain 11 score: 7.2 bits; conditional E-value: 0.013 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000336-T1 455 NSQSDFPKAIECYEKSLNIAREAGDR 480 689******************99776 PP == domain 12 score: 6.9 bits; conditional E-value: 0.017 DUF7018 67 dvqkllekaidhyekslklieeave 91 d q ++ kai+ yeksl++++ea + FUN_000336-T1 495 DSQSDFPKAIECYEKSLNIAREAGD 519 78*****************999855 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.0065 3.9 2 25 .. 46 69 .. 45 73 .. 0.93 2 ? 7.5 0.0 0.018 11 1 25 [. 85 109 .. 85 113 .. 0.92 3 ? 5.1 0.0 0.1 59 5 25 .. 129 149 .. 125 153 .. 0.89 4 ! 10.2 0.0 0.0024 1.4 1 25 [. 165 189 .. 165 193 .. 0.93 5 ? 3.2 0.0 0.4 2.4e+02 6 25 .. 210 229 .. 206 233 .. 0.91 6 ? 6.7 0.0 0.032 19 3 25 .. 287 309 .. 286 313 .. 0.91 7 ? 6.7 0.0 0.032 19 3 25 .. 367 389 .. 366 393 .. 0.91 8 ? 3.6 0.0 0.31 1.8e+02 5 25 .. 409 429 .. 405 433 .. 0.89 9 ! 9.1 0.0 0.0055 3.3 1 25 [. 445 469 .. 445 473 .. 0.93 10 ! 10.3 0.0 0.0022 1.3 1 25 [. 485 509 .. 485 513 .. 0.93 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0065 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+l+l+ +y + d+ +A++ +++ FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEK 69 89********************98 PP == domain 2 score: 7.5 bits; conditional E-value: 0.018 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+++y d+ +A++ +++ FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEK 109 789*********88*********98 PP == domain 3 score: 5.1 bits; conditional E-value: 0.1 TPR_6 5 klalsylelgdkdeAkaalqr 25 +l+++y+ + d+ +A++ +++ FUN_000336-T1 129 NLGVAYKSQSDFPKAIECYEK 149 69*****************98 PP == domain 4 score: 10.2 bits; conditional E-value: 0.0024 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+++y + d+ +A++ +++ FUN_000336-T1 165 DVYYNLGVAYDSQSDFPKAIESYEK 189 789********************98 PP == domain 5 score: 3.2 bits; conditional E-value: 0.4 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+++y + d+ +A++ +++ FUN_000336-T1 210 LGVAYNSQSDFPKAIECYEK 229 899****99*********98 PP == domain 6 score: 6.7 bits; conditional E-value: 0.032 TPR_6 3 llklalsylelgdkdeAkaalqr 25 ++ l+++y + d+ +A++ +++ FUN_000336-T1 287 YYDLGVAYDSQSDFPKAIECYEK 309 899******************98 PP == domain 7 score: 6.7 bits; conditional E-value: 0.032 TPR_6 3 llklalsylelgdkdeAkaalqr 25 ++ l+++y + d+ +A++ +++ FUN_000336-T1 367 YYDLGVAYNSQSDFPKAIECYEK 389 899******************98 PP == domain 8 score: 3.6 bits; conditional E-value: 0.31 TPR_6 5 klalsylelgdkdeAkaalqr 25 +l++ y+ + d+ +A++ +++ FUN_000336-T1 409 NLGVTYKSQSDFPKAIECYEK 429 699*****9**********98 PP == domain 9 score: 9.1 bits; conditional E-value: 0.0055 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d+++ l+++y + d+ +A++ +++ FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIECYEK 469 789********************98 PP == domain 10 score: 10.3 bits; conditional E-value: 0.0022 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+++y + d+ +A++ +++ FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEK 509 789********************98 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.0054 3.2 19 58 .. 30 71 .. 20 81 .. 0.83 2 ! 10.1 0.0 0.002 1.2 1 58 [. 48 111 .. 48 120 .. 0.81 3 ? 4.4 0.0 0.12 74 30 58 .. 123 151 .. 107 161 .. 0.69 4 ! 13.1 0.0 0.00024 0.14 3 58 .. 130 191 .. 128 201 .. 0.77 5 ? 5.2 0.0 0.071 42 31 58 .. 204 231 .. 191 239 .. 0.83 6 ? -0.1 0.0 3.3 1.9e+03 31 51 .. 244 264 .. 227 266 .. 0.77 7 ? 6.3 0.0 0.033 20 34 58 .. 287 311 .. 269 321 .. 0.77 8 ? 7.2 0.0 0.016 9.6 1 51 [. 288 344 .. 288 346 .. 0.72 9 ? 6.6 0.0 0.027 16 33 58 .. 366 391 .. 348 400 .. 0.83 10 ? 7.1 0.0 0.018 11 1 58 [. 368 431 .. 368 439 .. 0.72 11 ! 12.1 0.0 0.00049 0.29 6 58 .. 413 471 .. 408 481 .. 0.73 12 ! 8.1 0.0 0.0088 5.2 32 58 .. 485 511 .. 470 522 .. 0.81 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0054 TPR_16 19 aleaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 +l+ a++++ A+l+lG a+ q ++++A++ y++ l FUN_000336-T1 30 QLKIATKAGdrAGVGLAYLNLGIAYDSQSDFPKAIECYEKSL 71 66777777777677889*****************99998866 PP == domain 2 score: 10.1 bits; conditional E-value: 0.002 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l l+ a+ + d++ A++++e l + +++lG+a+ + ++++A++ y++ l FUN_000336-T1 48 LNLGIAYDSQSDFPKAIECYEKSLNIAgeagdrDWEKDVYFNLGVAYNSKSDFPKAIECYEKSL 111 578999999999999999998877655577777445689******************9998876 PP == domain 3 score: 4.4 bits; conditional E-value: 0.12 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraal 58 +A+ +lG+a+ q ++++A++ y++ l FUN_000336-T1 123 EGTAYCNLGVAYKSQSDFPKAIECYEKSL 151 67788888888888888888888777655 PP == domain 4 score: 13.1 bits; conditional E-value: 0.00024 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a+ + d++ A++++e l + +++lG+a+ q ++++A++ y++ l FUN_000336-T1 130 LGVAYKSQSDFPKAIECYEKSLNIAreagdrDCEKDVYYNLGVAYDSQSDFPKAIESYEKSL 191 677888888999999888765533334568844568********************999877 PP == domain 5 score: 5.2 bits; conditional E-value: 0.071 TPR_16 31 aaAllglGlallrqgrlaeAaaayraal 58 +A+ lG+a+ q ++++A++ y++ l FUN_000336-T1 204 GRAYCSLGVAYNSQSDFPKAIECYEKSL 231 578889***************9998866 PP == domain 6 score: -0.1 bits; conditional E-value: 3.3 TPR_16 31 aaAllglGlallrqgrlaeAa 51 +A+ lG+a+ q ++ +A+ FUN_000336-T1 244 GRAYCSLGVAYNSQSDFLKAI 264 5789999****9999999998 PP == domain 7 score: 6.3 bits; conditional E-value: 0.033 TPR_16 34 llglGlallrqgrlaeAaaayraal 58 ++ lG+a+ q ++++A++ y++ l FUN_000336-T1 287 YYDLGVAYDSQSDFPKAIECYEKSL 311 6778888888888888887777655 PP == domain 8 score: 7.2 bits; conditional E-value: 0.016 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAa 51 ++l+ a+ + d++ A++++e l +A+ lG+a+ q ++++A+ FUN_000336-T1 288 YDLGVAYDSQSDFPKAIECYEKSLNIAreagdqHTEGRAYCSLGVAYNSQSDFPKAI 344 788999999999999999998655322235577335678888888888888888887 PP == domain 9 score: 6.6 bits; conditional E-value: 0.027 TPR_16 33 AllglGlallrqgrlaeAaaayraal 58 ++ lG+a+ q ++++A++ y++ l FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSL 391 6899***************9998876 PP == domain 10 score: 7.1 bits; conditional E-value: 0.018 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 ++l+ a+ + d++ A++++e l + +A+ +lG+ + q ++++A++ y++ l FUN_000336-T1 368 YDLGVAYNSQSDFPKAIECYEKSLNIAreagdrRREGRAYCNLGVTYKSQSDFPKAIECYEKSL 431 6777777788888888888876543222356888888888888888888888888888777765 PP == domain 11 score: 12.1 bits; conditional E-value: 0.00049 TPR_16 6 aalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 + + d++ A++++e l + ++glG+a+ q ++++A++ y++ l FUN_000336-T1 413 TYKSQSDFPKAIECYEKSLNIAreagdrNGEKDVYYGLGVAYNSQSDFPKAIECYEKSL 471 566677777777777654422223457745789*******************9999876 PP == domain 12 score: 8.1 bits; conditional E-value: 0.0088 TPR_16 32 aAllglGlallrqgrlaeAaaayraal 58 + +++lG+a+ q ++++A++ y++ l FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEKSL 511 6799****************9999877 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.077 46 90 142 .. 20 71 .. 15 80 .. 0.74 2 ! 39.1 1.8 1.4e-12 8.2e-10 36 180 .. 85 229 .. 81 229 .. 0.92 3 ! 27.8 2.1 3.9e-09 2.3e-06 39 180 .. 208 349 .. 204 359 .. 0.90 4 ! 32.6 1.1 1.3e-10 8e-08 40 180 .. 329 469 .. 325 469 .. 0.94 5 ! 26.3 1.7 1.1e-08 6.7e-06 39 165 .. 408 534 .. 405 549 .. 0.90 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.077 SNAP 90 peeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAa 142 +eA++ ek +i t++g + + +++ y+++ +d+ kAie+Ye++ FUN_000336-T1 20 FQEALDKHEKQLKIATKAGDRAGVGLAYLNLGIAYDSQ-SDFPKAIECYEKSL 71 56777777777777777777777777778888888888.88888888888764 PP == domain 2 score: 39.1 bits; conditional E-value: 1.4e-12 SNAP 36 dlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqd 130 d+y + + ay + ++ +A e+++k ++ +++++++ ++ay++ +yk++ d +A+e++ek+ +i e+g + + + +++ y+++ +d FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEKSLNIAREAGDRHREGTAYCNLGVAYKSQsDFPKAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQ-SD 179 67777788999999*************************************985778************************************.** PP SNAP 131 lekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + kAie+Ye++ ++ ++ + + ++ + + ++ +++kAie yek FUN_000336-T1 180 FPKAIESYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFPKAIECYEK 229 **************9988877777777777766678899*********97 PP == domain 3 score: 27.8 bits; conditional E-value: 3.9e-09 SNAP 39 kqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlek 133 ++ + ay + ++ +A e+++k ++ +++++++ ++ay+ +y+++ d +A+e+ ek+ +i e+g + + +++ y+++ +d+ k FUN_000336-T1 208 CSLGVAYNSQSDFPKAIECYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQsDFLKAIECHEKSLNIAREAGDRDCEKIVYYDLGVAYDSQ-SDFPK 302 55567899999**********************************999875778************************************.***** PP SNAP 134 AieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 Aie+Ye++ ++ ++ + + + ++ + + ++ +++kAie ek FUN_000336-T1 303 AIECYEKSLNIAREAGDQHTEGRAYCSLGVAYNSQSDFPKAIECHEK 349 ***********9988877777776666666678899*******9997 PP == domain 4 score: 32.6 bits; conditional E-value: 1.3e-10 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + + ay + ++ +A e+++k ++ ++++++d y + +y+++ d +A+e++ek+ +i e+g rr ++ + +++ y+++ +d+ kA FUN_000336-T1 329 SLGVAYNSQSDFPKAIECHEKSLNIAREAGDRDCEKIVYYDLGVAYNSQsDFPKAIECYEKSLNIAREAGDRRREGRAYCNLGVTYKSQ-SDFPKA 423 55678999999*******************************99999875788************************************.****** PP SNAP 135 ieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 ie+Ye++ ++ ++ + + ++ + + ++ +++kAie yek FUN_000336-T1 424 IECYEKSLNIAREAGDRNGEKDVYYGLGVAYNSQSDFPKAIECYEK 469 *************99999999999999999999***********96 PP == domain 5 score: 26.3 bits; conditional E-value: 1.1e-08 SNAP 39 kqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlek 133 ++ + yk + ++ +A e+++k ++ +++++++ + y +y+++ d +A+e++ek+ +i e+g + + + +++ y+++ +d+ k FUN_000336-T1 408 CNLGVTYKSQSDFPKAIECYEKSLNIAREAGDRNGEKDVYYGLGVAYNSQsDFPKAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQ-SDFPK 502 555678*********************************999999998875788************************************.***** PP SNAP 134 AieaYeqAadlyeqeeaealankcllkvAdls 165 Aie+Ye++ ++ ++ + +a + vA+ + FUN_000336-T1 503 AIECYEKSLNIAREAGDQAAVRRASHYVAECY 534 ********999999888888888888888765 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.32 1.9e+02 54 114 .. 18 78 .. 12 83 .. 0.80 2 ! 18.8 0.0 1.9e-06 0.0011 16 114 .. 59 158 .. 54 164 .. 0.84 3 ! 23.7 0.0 5.9e-08 3.5e-05 42 156 .. 166 279 .. 159 284 .. 0.92 4 ! 15.6 0.0 1.8e-05 0.011 42 155 .. 246 357 .. 242 363 .. 0.86 5 ! 12.8 0.0 0.00012 0.073 13 111 .. 296 395 .. 282 396 .. 0.48 6 ! 18.6 0.0 2.2e-06 0.0013 40 155 .. 364 477 .. 337 480 .. 0.75 7 ! 22.5 0.0 1.4e-07 8.2e-05 11 162 .. 374 524 .. 371 540 .. 0.90 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.32 TPR_MalT 54 gdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesk 114 g +++Al+ ++ ++a +a++ + la+l ++ + q ++ +A+e y++ l a+e++ FUN_000336-T1 18 GSFQEALDKHEKQLKIATKAGDRAGVGLAYLNLGIAYDSQSDFPKAIECYEKSLNIAGEAG 78 6677788877777888888888888889999999999999999999999999999988765 PP == domain 2 score: 18.8 bits; conditional E-value: 1.9e-06 TPR_MalT 16 eaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 ++++a+e ++ L++ e d + ++++lG+a+ + d+ +A + +++ +ar+a++ h+ a++ ++ + q ++ +A+e y++ l a FUN_000336-T1 59 DFPKAIECYEKSLNIAGEAgDRDWEKDVYFNLGVAYNSKSDFPKAIECYEKSLNIAREAGDRHREGTAYCNLGVAYKSQSDFPKAIECYEKSLNIA 154 55555555555565554432456667789******************************************************************* PP TPR_MalT 111 qesk 114 +e++ FUN_000336-T1 155 REAG 158 9976 PP == domain 3 score: 23.7 bits; conditional E-value: 5.9e-08 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 ++++lG+a+ q d+ +A +++++ +ar+a++ h a+++++ + q ++ +A+e y++ l a+e++ ++ + g ++ +l+ + + d FUN_000336-T1 166 VYYNLGVAYDSQSDFPKAIESYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFPKAIECYEKSLNIAREAGDRH--TEGRAYCSLGVAYNSQSD 259 6799********************************99*************************************9..66788889999999999* PP TPR_MalT 138 LeeAeqhlqqgiqlgrql.e 156 + +A ++ +++++++r++ + FUN_000336-T1 260 FLKAIECHEKSLNIAREAgD 279 99999999999999998734 PP == domain 4 score: 15.6 bits; conditional E-value: 1.8e-05 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 a+ +lG+a+ q d+ +A + ++ +ar+a++ + + ++ ++ + q ++ +A+e y++ l a+e++ ++ + g ++ +l+ + + d FUN_000336-T1 246 AYCSLGVAYNSQSDFLKAIECHEKSLNIAREAGDRDCEKIVYYDLGVAYDSQSDFPKAIECYEKSLNIAREAGDQH--TEGRAYCSLGVAYNSQSD 339 7788999999999999999999999999999999999999999999999999999999999999999999999998..567888899999999999 PP TPR_MalT 138 LeeAeqhlqqgiqlgrql 155 + +A ++ +++++++r++ FUN_000336-T1 340 FPKAIECHEKSLNIAREA 357 999999999999999986 PP == domain 5 score: 12.8 bits; conditional E-value: 0.00012 TPR_MalT 13 sqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 sq ++++a+e ++ L++ +e d + + a+ +lG+a+ q d+ +A + ++ +ar+a++ + + ++ ++ + q ++ +A+e y++ l FUN_000336-T1 296 SQSDFPKAIECYEKSLNIAREAgDQHTEGRAYCSLGVAYNSQSDFPKAIECHEKSLNIAREAGDRDCEKIVYYDLGVAYNSQSDFPKAIECYEKSL 391 344455555555555555544312233345555555555555555555555555555555555555555555555555555555555555555555 PP TPR_MalT 108 qlaq 111 a+ FUN_000336-T1 392 NIAR 395 5444 PP == domain 6 score: 18.6 bits; conditional E-value: 2.2e-06 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 ++++ lG+a+ q d+ +A + +++ +ar+a++ ++ a++ ++ ++ q ++ +A+e y++ l a+e++ ++ ++ gl+ + + FUN_000336-T1 364 KIVYYDLGVAYNSQSDFPKAIECYEKSLNIAREAGDRRREGRAYCNLGVTYKSQSDFPKAIECYEKSLNIAREAGDRN--GEKDVYYGLGVAYNSQ 457 456678888999999999999999999999999999988888999999999999999999999999999998888886..6677777888888888 PP TPR_MalT 136 ndLeeAeqhlqqgiqlgrql 155 d+ +A ++ +++++++r++ FUN_000336-T1 458 SDFPKAIECYEKSLNIAREA 477 88888888888888887765 PP == domain 7 score: 22.5 bits; conditional E-value: 1.4e-07 TPR_MalT 11 avsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 + sq ++++a+e ++ L++ +e r + a+ +lG+++ q d+ +A + +++ +ar+a++ + +++++ + q ++ +A+e y++ FUN_000336-T1 374 YNSQSDFPKAIECYEKSLNIAREAGDRRReGRAYCNLGVTYKSQSDFPKAIECYEKSLNIAREAGDRNGEKDVYYGLGVAYNSQSDFPKAIECYEK 469 56789999*************9998788889***************************************************************** PP TPR_MalT 106 alqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrqlepaaale 162 l a+e++ + ++ l+ + + d+ +A ++ +++++++r+++ +aa++ FUN_000336-T1 470 SLNIAREAGDRD--CEKDVYYNLGVAYDSQSDFPKAIECYEKSLNIAREAGDQAAVR 524 *********996..667788899999***********************98888876 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.19 1.2e+02 186 212 .. 54 80 .. 19 87 .. 0.84 2 ! 8.6 0.0 0.0031 1.8 136 212 .. 85 160 .. 84 169 .. 0.74 3 ! 7.2 0.0 0.0087 5.1 139 213 .. 168 241 .. 164 246 .. 0.67 4 ! 8.5 0.0 0.0033 2 148 213 .. 257 321 .. 245 325 .. 0.65 5 ! 7.5 0.0 0.0069 4.1 144 211 .. 333 399 .. 324 401 .. 0.72 6 ? 4.2 0.0 0.071 42 187 212 .. 415 440 .. 407 448 .. 0.87 7 ? 4.3 0.0 0.063 38 188 213 .. 456 481 .. 444 490 .. 0.85 8 ? 4.9 0.0 0.043 26 188 213 .. 496 521 .. 483 527 .. 0.86 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.19 ComR_TPR 186 lkvkkdfkkAkelYqkaimfakllgde 212 + + df kA e+Y+k++ a gd FUN_000336-T1 54 YDSQSDFPKAIECYEKSLNIAGEAGDR 80 56689*************999888876 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0031 ComR_TPR 136 dvllsalavllllkdyekleellkvlkeiidktqdfqkk.pivlmlewkyylkvkkdfkkAkelYqkaimfakllgde 212 dv++++ +++ ++ d+ k e+ +++ +i +++ d ++ ++ l y + df kA e+Y+k++ a+ gd FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEKSLNIAREAGDRHREgTAYCNLGVAYKS--QSDFPKAIECYEKSLNIAREAGDR 160 5667777777778888888888888888888887766551455666666665..999999999999999999988886 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0087 ComR_TPR 139 lsalavllllkdyekleellkvlkeiidktqd.fqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 ++ +++ + d+ k e +++ +i +++ d +++ ++ l y + df kA e+Y+k++ a+ gd + FUN_000336-T1 168 YNLGVAYDSQSDFPKAIESYEKSLNIAREAGDrHTEGRAYCSLGVAYNS--QSDFPKAIECYEKSLNIAREAGDRH 241 5555666666666666666666667776665513444556666666665..8899999999999999999888876 PP == domain 4 score: 8.5 bits; conditional E-value: 0.0033 ComR_TPR 148 lkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 d+ k e+ +++ +i +++ d +k++++ l y + df kA e+Y+k++ a+ gd++ FUN_000336-T1 257 QSDFLKAIECHEKSLNIAREAGDRDcEKIVYYDLGVAYDS--QSDFPKAIECYEKSLNIAREAGDQH 321 3333333344444444555544433256666666666666..9********************9987 PP == domain 5 score: 7.5 bits; conditional E-value: 0.0069 ComR_TPR 144 vllllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 ++ + d+ k e+ +++ +i +++ d +k++++ l y + df kA e+Y+k++ a+ gd FUN_000336-T1 333 AYNSQSDFPKAIECHEKSLNIAREAGDRDcEKIVYYDLGVAYNS--QSDFPKAIECYEKSLNIAREAGD 399 45555566666666666667777766654267777777777777..9*****************99888 PP == domain 6 score: 4.2 bits; conditional E-value: 0.071 ComR_TPR 187 kvkkdfkkAkelYqkaimfakllgde 212 k + df kA e+Y+k++ a+ gd FUN_000336-T1 415 KSQSDFPKAIECYEKSLNIAREAGDR 440 45899***************999996 PP == domain 7 score: 4.3 bits; conditional E-value: 0.063 ComR_TPR 188 vkkdfkkAkelYqkaimfakllgdev 213 + df kA e+Y+k++ a+ gd FUN_000336-T1 456 SQSDFPKAIECYEKSLNIAREAGDRD 481 5889****************999975 PP == domain 8 score: 4.9 bits; conditional E-value: 0.043 ComR_TPR 188 vkkdfkkAkelYqkaimfakllgdev 213 + df kA e+Y+k++ a+ gd++ FUN_000336-T1 496 SQSDFPKAIECYEKSLNIAREAGDQA 521 5899****************999986 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.19 1.1e+02 35 65 .. 50 80 .. 45 83 .. 0.68 2 ! 9.1 0.0 0.003 1.8 4 66 .. 93 161 .. 90 164 .. 0.90 3 ? 4.7 0.0 0.076 45 4 65 .. 133 200 .. 130 203 .. 0.65 4 ? 6.1 0.0 0.028 16 4 52 .. 213 260 .. 210 282 .. 0.73 5 ? 3.7 0.0 0.15 90 5 58 .. 294 353 .. 290 365 .. 0.60 6 ? 6.9 0.0 0.015 9.1 32 67 .. 367 402 .. 330 403 .. 0.71 7 ! 10.2 0.0 0.0014 0.83 4 57 .. 373 425 .. 370 441 .. 0.81 8 ? 5.3 0.0 0.048 28 4 65 .. 413 480 .. 410 484 .. 0.71 9 ? 7.0 0.0 0.014 8.3 4 70 .. 453 525 .. 450 528 .. 0.78 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.19 TPR_9 35 rGllyaqlgcleaAladLeaylalapdapda 65 G++y + ++ +A+++ e+ l +a +a d+ FUN_000336-T1 50 LGIAYDSQSDFPKAIECYEKSLNIAGEAGDR 80 6777777777777777777777777766665 PP == domain 2 score: 9.1 bits; conditional E-value: 0.003 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 +y ++ d+++a++++e l + ++++ + + + G +y + ++ +A+++ e+ l +a +a d++ FUN_000336-T1 93 AYNSKSDFPKAIECYEKSLNIareagdRHREGTAYCNLGVAYKSQSDFPKAIECYEKSLNIAREAGDRD 161 577899***************9999999999999999*******************9999999998886 PP == domain 3 score: 4.7 bits; conditional E-value: 0.076 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 +y ++ d+++a++++e l + + + + +++ G +y + ++ +A++ e+ l +a +a d+ FUN_000336-T1 133 AYKSQSDFPKAIECYEKSLNIareagdRDCEKDVYYNLGVAYDSQSDFPKAIESYEKSLNIAREAGDR 200 67888899999999998888744433222233456677777777777777777777777666666665 PP == domain 4 score: 6.1 bits; conditional E-value: 0.028 TPR_9 4 iyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladL 52 +y ++ d+++a++++e l +a +++++r G++y lg + d+ FUN_000336-T1 213 AYNSQSDFPKAIECYEKSLNIA-REAGDRHTEGRAYCSLGVAYNSQSDF 260 677899************9995.77888888888888887665555555 PP == domain 5 score: 3.7 bits; conditional E-value: 0.15 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylal 58 y ++ d+++a++++e l + ++ + + + G +y + ++ +A+++ e+ l + FUN_000336-T1 294 YDSQSDFPKAIECYEKSLNIareagdQHTEGRAYCSLGVAYNSQSDFPKAIECHEKSLNI 353 667889999999999988885554444444444444555555555555555555555555 PP == domain 6 score: 6.9 bits; conditional E-value: 0.015 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalapdapdaea 67 ++d G +y + ++ +A+++ e+ l +a +a d+++ FUN_000336-T1 367 YYDLGVAYNSQSDFPKAIECYEKSLNIAREAGDRRR 402 789999999999999999999999999999999875 PP == domain 7 score: 10.2 bits; conditional E-value: 0.0014 TPR_9 4 iyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y ++ d+++a++++e l +a +++++rr G++y +lg + ++ d+ ++++ FUN_000336-T1 373 AYNSQSDFPKAIECYEKSLNIA-REAGDRRREGRAYCNLGVTYKSQSDFPKAIE 425 678899***************6.9999999999999999988877777766664 PP == domain 8 score: 5.3 bits; conditional E-value: 0.048 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 y ++ d+++a++++e l + + + + ++ G +y + ++ +A+++ e+ l +a +a d+ FUN_000336-T1 413 TYKSQSDFPKAIECYEKSLNIareagdRNGEKDVYYGLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 480 57788888888888888888855555555555666677778888888888888888777777777776 PP == domain 9 score: 7.0 bits; conditional E-value: 0.014 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdaeaire 70 +y ++ d+++a++++e l + + + + +++ G +y + ++ +A+++ e+ l +a +a d +a+r+ FUN_000336-T1 453 AYNSQSDFPKAIECYEKSLNIareagdRDCEKDVYYNLGVAYDSQSDFPKAIECYEKSLNIAREAGDQAAVRR 525 5677888888888888888885554433334456899999999999999999999999999999999888886 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.1 0.0016 0.94 5 32 .. 45 72 .. 43 77 .. 0.91 2 ? 5.3 0.1 0.05 30 9 32 .. 89 112 .. 87 119 .. 0.87 3 ? 4.7 0.1 0.075 45 7 33 .. 127 153 .. 122 165 .. 0.82 4 ? 7.4 0.0 0.011 6.6 10 32 .. 170 192 .. 167 205 .. 0.89 5 ? 4.7 0.0 0.077 46 11 32 .. 211 232 .. 203 246 .. 0.85 6 ? -1.5 0.0 6.9 4.1e+03 11 32 .. 251 272 .. 242 280 .. 0.80 7 ! 8.5 0.0 0.0051 3 11 32 .. 291 312 .. 287 326 .. 0.89 8 ? -0.3 0.0 2.9 1.7e+03 11 32 .. 331 352 .. 323 359 .. 0.84 9 ? 4.0 0.0 0.13 75 12 32 .. 372 392 .. 368 404 .. 0.85 10 ? 4.0 0.0 0.12 74 11 33 .. 411 433 .. 402 445 .. 0.80 11 ? 4.0 0.0 0.13 75 12 33 .. 452 473 .. 449 485 .. 0.84 12 ! 8.8 0.3 0.0041 2.4 10 32 .. 490 512 .. 487 527 .. 0.89 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.0016 MIT 5 lelvkkAveeDnagnyeeAlelYkeale 32 l++++ + +D++ ++ +A+e+Y+++l+ FUN_000336-T1 45 LAYLNLGIAYDSQSDFPKAIECYEKSLN 72 6788999******************997 PP == domain 2 score: 5.3 bits; conditional E-value: 0.05 MIT 9 kkAveeDnagnyeeAlelYkeale 32 + v + ++ ++ +A+e+Y+++l+ FUN_000336-T1 89 NLGVAYNSKSDFPKAIECYEKSLN 112 667889999************997 PP == domain 3 score: 4.7 bits; conditional E-value: 0.075 MIT 7 lvkkAveeDnagnyeeAlelYkealel 33 + + v + ++ ++ +A+e+Y+++l+ FUN_000336-T1 127 YCNLGVAYKSQSDFPKAIECYEKSLNI 153 5677788889999**********9985 PP == domain 4 score: 7.4 bits; conditional E-value: 0.011 MIT 10 kAveeDnagnyeeAlelYkeale 32 v +D++ ++ +A+e Y+++l+ FUN_000336-T1 170 LGVAYDSQSDFPKAIESYEKSLN 192 5799****************997 PP == domain 5 score: 4.7 bits; conditional E-value: 0.077 MIT 11 AveeDnagnyeeAlelYkeale 32 v + ++ ++ +A+e+Y+++l+ FUN_000336-T1 211 GVAYNSQSDFPKAIECYEKSLN 232 678889999**********997 PP == domain 6 score: -1.5 bits; conditional E-value: 6.9 MIT 11 AveeDnagnyeeAlelYkeale 32 v + ++ ++ +A+e+ +++l+ FUN_000336-T1 251 GVAYNSQSDFLKAIECHEKSLN 272 5777788888999999999886 PP == domain 7 score: 8.5 bits; conditional E-value: 0.0051 MIT 11 AveeDnagnyeeAlelYkeale 32 v +D++ ++ +A+e+Y+++l+ FUN_000336-T1 291 GVAYDSQSDFPKAIECYEKSLN 312 589****************997 PP == domain 8 score: -0.3 bits; conditional E-value: 2.9 MIT 11 AveeDnagnyeeAlelYkeale 32 v + ++ ++ +A+e+ +++l+ FUN_000336-T1 331 GVAYNSQSDFPKAIECHEKSLN 352 6778889999*******99987 PP == domain 9 score: 4.0 bits; conditional E-value: 0.13 MIT 12 veeDnagnyeeAlelYkeale 32 v + ++ ++ +A+e+Y+++l+ FUN_000336-T1 372 VAYNSQSDFPKAIECYEKSLN 392 667788999*********997 PP == domain 10 score: 4.0 bits; conditional E-value: 0.12 MIT 11 AveeDnagnyeeAlelYkealel 33 v + ++ ++ +A+e+Y+++l+ FUN_000336-T1 411 GVTYKSQSDFPKAIECYEKSLNI 433 5667778899**********985 PP == domain 11 score: 4.0 bits; conditional E-value: 0.13 MIT 12 veeDnagnyeeAlelYkealel 33 v + ++ ++ +A+e+Y+++l+ FUN_000336-T1 452 VAYNSQSDFPKAIECYEKSLNI 473 667788899*********9985 PP == domain 12 score: 8.8 bits; conditional E-value: 0.0041 MIT 10 kAveeDnagnyeeAlelYkeale 32 v +D++ ++ +A+e+Y+++l+ FUN_000336-T1 490 LGVAYDSQSDFPKAIECYEKSLN 512 5799****************997 PP >> Cerato-platanin Cerato-platanin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 6.9 4.1e+03 64 92 .. 51 79 .. 32 87 .. 0.86 2 ? 4.5 0.0 0.088 53 64 100 .. 91 127 .. 73 143 .. 0.88 3 ? -0.2 0.0 2.5 1.5e+03 64 93 .. 131 160 .. 118 168 .. 0.85 4 ? 6.1 0.0 0.028 17 64 100 .. 171 207 .. 162 212 .. 0.90 5 ? 6.4 0.0 0.022 13 64 100 .. 211 247 .. 206 252 .. 0.90 6 ? 4.6 0.0 0.082 48 63 92 .. 250 279 .. 244 287 .. 0.88 7 ? 6.5 0.0 0.021 12 64 100 .. 291 327 .. 281 333 .. 0.90 8 ? 1.6 0.0 0.68 4.1e+02 64 92 .. 331 359 .. 326 365 .. 0.89 9 ? 3.0 0.0 0.26 1.5e+02 64 99 .. 371 406 .. 361 414 .. 0.88 10 ? 1.1 0.0 1 6e+02 64 93 .. 411 440 .. 405 449 .. 0.88 11 ? 1.0 0.0 1.1 6.4e+02 64 93 .. 451 480 .. 445 491 .. 0.88 12 ? 2.0 0.0 0.51 3e+02 64 99 .. 491 526 .. 481 531 .. 0.87 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 6.9 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamd 92 +i y++++ + ai+ + +nia +a d FUN_000336-T1 51 GIAYDSQSDFPKAIECYEKSLNIAGEAGD 79 68999999999999999999999988866 PP == domain 2 score: 4.5 bits; conditional E-value: 0.088 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa 100 ++ yn+k+ + ai+ + +nia++a d+ +g+a FUN_000336-T1 91 GVAYNSKSDFPKAIECYEKSLNIAREAGDRHREGTAY 127 689************************9999888874 PP == domain 3 score: -0.2 bits; conditional E-value: 2.5 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamde 93 ++ y++++ + ai+ + +nia++a d+ FUN_000336-T1 131 GVAYKSQSDFPKAIECYEKSLNIAREAGDR 160 6899999******************99775 PP == domain 4 score: 6.1 bits; conditional E-value: 0.028 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa 100 ++ y++++ + ai++ + +nia++a d+ t+g+a FUN_000336-T1 171 GVAYDSQSDFPKAIESYEKSLNIAREAGDRHTEGRAY 207 589******************************9984 PP == domain 5 score: 6.4 bits; conditional E-value: 0.022 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa 100 ++ yn+++ + ai+ + +nia++a d+ t+g+a FUN_000336-T1 211 GVAYNSQSDFPKAIECYEKSLNIAREAGDRHTEGRAY 247 699******************************9984 PP == domain 6 score: 4.6 bits; conditional E-value: 0.082 Cerato-platanin 63 ykityngktiyvlaidaagaGfniakkamd 92 ++ yn+++ ++ ai+ + +nia++a d FUN_000336-T1 250 LGVAYNSQSDFLKAIECHEKSLNIAREAGD 279 4799**********************9977 PP == domain 7 score: 6.5 bits; conditional E-value: 0.021 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa 100 ++ y++++ + ai+ + +nia++a d+ t+g+a FUN_000336-T1 291 GVAYDSQSDFPKAIECYEKSLNIAREAGDQHTEGRAY 327 58999*****************************984 PP == domain 8 score: 1.6 bits; conditional E-value: 0.68 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamd 92 ++ yn+++ + ai+ + +nia++a d FUN_000336-T1 331 GVAYNSQSDFPKAIECHEKSLNIAREAGD 359 699**********************9977 PP == domain 9 score: 3.0 bits; conditional E-value: 0.26 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqa 99 ++ yn+++ + ai+ + +nia++a d+ +g+a FUN_000336-T1 371 GVAYNSQSDFPKAIECYEKSLNIAREAGDRRREGRA 406 589************************999888877 PP == domain 10 score: 1.1 bits; conditional E-value: 1 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamde 93 ++ty++++ + ai+ + +nia++a d+ FUN_000336-T1 411 GVTYKSQSDFPKAIECYEKSLNIAREAGDR 440 79***********************99875 PP == domain 11 score: 1.0 bits; conditional E-value: 1.1 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamde 93 ++ yn+++ + ai+ + +nia++a d+ FUN_000336-T1 451 GVAYNSQSDFPKAIECYEKSLNIAREAGDR 480 689**********************99875 PP == domain 12 score: 2.0 bits; conditional E-value: 0.51 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqa 99 ++ y++++ + ai+ + +nia++a d+ + +a FUN_000336-T1 491 GVAYDSQSDFPKAIECYEKSLNIAREAGDQAAVRRA 526 58999**********************999877666 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.15 90 136 173 .. 46 82 .. 31 86 .. 0.89 2 ? 4.4 0.1 0.069 41 147 174 .. 85 123 .. 63 126 .. 0.68 3 ? 6.2 0.0 0.02 12 136 174 .. 126 163 .. 124 166 .. 0.90 4 ? -0.2 0.0 1.8 1.1e+03 149 174 .. 178 203 .. 167 206 .. 0.79 5 ? 7.0 0.1 0.011 6.5 147 174 .. 200 243 .. 181 246 .. 0.68 6 ? 4.1 0.0 0.089 53 135 172 .. 245 281 .. 244 286 .. 0.89 7 ? 2.4 0.0 0.28 1.7e+02 149 174 .. 298 323 .. 287 326 .. 0.83 8 ? 3.5 0.0 0.13 76 135 172 .. 325 361 .. 324 366 .. 0.88 9 ? 3.6 0.0 0.12 72 150 174 .. 379 403 .. 367 406 .. 0.84 10 ! 8.3 0.0 0.0043 2.5 135 175 .. 405 444 .. 404 446 .. 0.92 11 ? 2.4 0.0 0.29 1.7e+02 150 174 .. 459 483 .. 450 486 .. 0.83 12 ? 4.4 0.1 0.069 41 133 173 .. 463 522 .. 462 526 .. 0.70 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.15 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrke 173 aYl+ +++ + +a++++e++l +a ++g+r+ FUN_000336-T1 46 AYLNLGIAYDSQ-SDFPKAIECYEKSLNIAGEAGDRDW 82 899999999998.999***************9999875 PP == domain 2 score: 4.4 bits; conditional E-value: 0.069 DUF7380 147 g...........seewvdalkrleRAlqlaaqlgkrkee 174 + +a++++e++l +a+++g+r +e FUN_000336-T1 85 DvyfnlgvaynsKSDFPKAIECYEKSLNIAREAGDRHRE 123 055555555554477899****************99887 PP == domain 3 score: 6.2 bits; conditional E-value: 0.02 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aY++ +++ + +a++++e++l +a+++g+r+ e FUN_000336-T1 126 AYCNLGVAYKSQ-SDFPKAIECYEKSLNIAREAGDRDCE 163 899999999999.999******************99865 PP == domain 4 score: -0.2 bits; conditional E-value: 1.8 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkee 174 + +a++ +e++l +a+++g+r +e FUN_000336-T1 178 SDFPKAIESYEKSLNIAREAGDRHTE 203 45778899999999999999998776 PP == domain 5 score: 7.0 bits; conditional E-value: 0.011 DUF7380 147 g................seewvdalkrleRAlqlaaqlgkrkee 174 + + +a++++e++l +a+++g+r +e FUN_000336-T1 200 RhtegraycslgvaynsQSDFPKAIECYEKSLNIAREAGDRHTE 243 2556666666655555448999*****************99876 PP == domain 6 score: 4.1 bits; conditional E-value: 0.089 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrk 172 +aY++ ++ +++a+++ e++l +a+++g+r+ FUN_000336-T1 245 RAYCSLGVAYNSQ-SDFLKAIECHEKSLNIAREAGDRD 281 5899988888888.999*****************9997 PP == domain 7 score: 2.4 bits; conditional E-value: 0.28 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkee 174 + +a++++e++l +a+++g++ +e FUN_000336-T1 298 SDFPKAIECYEKSLNIAREAGDQHTE 323 457899**************999876 PP == domain 8 score: 3.5 bits; conditional E-value: 0.13 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrk 172 +aY++ ++ + +a+++ e++l +a+++g+r+ FUN_000336-T1 325 RAYCSLGVAYNSQ-SDFPKAIECHEKSLNIAREAGDRD 361 5899988888888.8999****************9997 PP == domain 9 score: 3.6 bits; conditional E-value: 0.12 DUF7380 150 ewvdalkrleRAlqlaaqlgkrkee 174 + +a++++e++l +a+++g+r++e FUN_000336-T1 379 DFPKAIECYEKSLNIAREAGDRRRE 403 57899****************9987 PP == domain 10 score: 8.3 bits; conditional E-value: 0.0043 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 +aY++ +++ + +a++++e++l +a+++g+r+ e+ FUN_000336-T1 405 RAYCNLGVTYKSQ-SDFPKAIECYEKSLNIAREAGDRNGEK 444 6999999999999.999********************9886 PP == domain 11 score: 2.4 bits; conditional E-value: 0.29 DUF7380 150 ewvdalkrleRAlqlaaqlgkrkee 174 + +a++++e++l +a+++g+r+ e FUN_000336-T1 459 DFPKAIECYEKSLNIAREAGDRDCE 483 47899***************99865 PP == domain 12 score: 4.4 bits; conditional E-value: 0.069 DUF7380 133 AidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrke 173 Ai++Y +s + +++ + +a++++e++l +a+++g+++ FUN_000336-T1 463 AIECYEKSLNIAREAgdrdcekdvyynlgvaydsQSDFPKAIECYEKSLNIAREAGDQAA 522 6666655444444444447777777777777776678889999********999999875 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.12 71 4 31 .. 47 70 .. 43 72 .. 0.68 2 ? 4.5 0.0 0.13 80 18 31 .. 97 110 .. 85 112 .. 0.76 3 ? 4.1 0.0 0.19 1.1e+02 18 31 .. 137 150 .. 125 152 .. 0.70 4 ? 3.3 0.0 0.34 2e+02 19 31 .. 218 230 .. 205 232 .. 0.81 5 ? -1.2 0.0 8.9 5.3e+03 20 31 .. 259 270 .. 246 272 .. 0.79 6 ? 4.2 0.0 0.17 1e+02 18 31 .. 297 310 .. 286 312 .. 0.71 7 ? -0.5 0.0 5.4 3.2e+03 19 31 .. 338 350 .. 325 352 .. 0.78 8 ? 3.8 0.0 0.24 1.4e+02 18 31 .. 377 390 .. 366 392 .. 0.74 9 ? 4.2 0.0 0.18 1.1e+02 18 31 .. 417 430 .. 404 432 .. 0.70 10 ? 4.9 0.0 0.11 64 13 31 .. 448 470 .. 445 472 .. 0.71 11 ? 5.3 0.0 0.08 47 5 31 .. 488 510 .. 485 512 .. 0.74 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.12 Sel1 4 qyrLGylylyGlgvpkDpekAlewyekA 31 + +LG y D kA+e+yek+ FUN_000336-T1 47 YLNLGI--AYD--SQSDFPKAIECYEKS 70 445553..222..3569*********96 PP == domain 2 score: 4.5 bits; conditional E-value: 0.13 Sel1 18 pkDpekAlewyekA 31 + D kA+e+yek+ FUN_000336-T1 97 KSDFPKAIECYEKS 110 789*********96 PP == domain 3 score: 4.1 bits; conditional E-value: 0.19 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000336-T1 137 QSDFPKAIECYEKS 150 3499********96 PP == domain 4 score: 3.3 bits; conditional E-value: 0.34 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000336-T1 218 SDFPKAIECYEKS 230 4999*******96 PP == domain 5 score: -1.2 bits; conditional E-value: 8.9 Sel1 20 DpekAlewyekA 31 D kA+e+ ek+ FUN_000336-T1 259 DFLKAIECHEKS 270 888999999986 PP == domain 6 score: 4.2 bits; conditional E-value: 0.17 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000336-T1 297 QSDFPKAIECYEKS 310 4599********96 PP == domain 7 score: -0.5 bits; conditional E-value: 5.4 Sel1 19 kDpekAlewyekA 31 D kA+e+ ek+ FUN_000336-T1 338 SDFPKAIECHEKS 350 4899999999986 PP == domain 8 score: 3.8 bits; conditional E-value: 0.24 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000336-T1 377 QSDFPKAIECYEKS 390 45999*******96 PP == domain 9 score: 4.2 bits; conditional E-value: 0.18 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000336-T1 417 QSDFPKAIECYEKS 430 3499********96 PP == domain 10 score: 4.9 bits; conditional E-value: 0.11 Sel1 13 yGlgvpk....DpekAlewyekA 31 yGlgv D kA+e+yek+ FUN_000336-T1 448 YGLGVAYnsqsDFPKAIECYEKS 470 5555444344599********96 PP == domain 11 score: 5.3 bits; conditional E-value: 0.08 Sel1 5 yrLGylylyGlgvpkDpekAlewyekA 31 y+LG y + D kA+e+yek+ FUN_000336-T1 488 YNLGV--AYDS--QSDFPKAIECYEKS 510 67775..4443..56**********96 PP >> TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.3 1.8e+02 55 70 .. 57 72 .. 51 78 .. 0.83 2 ? 3.2 0.0 0.18 1.1e+02 55 71 .. 97 113 .. 91 122 .. 0.80 3 ? 3.3 0.0 0.18 1e+02 55 71 .. 137 153 .. 129 160 .. 0.81 4 ? 0.6 0.0 1.2 6.9e+02 55 73 .. 177 195 .. 171 212 .. 0.79 5 ? 3.6 0.0 0.14 84 55 73 .. 217 235 .. 210 256 .. 0.79 6 ? -1.4 0.0 5 3e+03 55 70 .. 257 272 .. 250 277 .. 0.80 7 ? 3.7 0.0 0.13 79 55 75 .. 297 317 .. 291 338 .. 0.77 8 ? -1.0 0.0 3.6 2.2e+03 55 70 .. 337 352 .. 330 357 .. 0.80 9 ? 3.2 0.0 0.18 1.1e+02 55 72 .. 377 394 .. 371 415 .. 0.83 10 ? 2.6 0.0 0.28 1.6e+02 55 71 .. 417 433 .. 411 438 .. 0.83 11 ? 2.9 0.0 0.23 1.4e+02 55 71 .. 457 473 .. 451 479 .. 0.82 12 ! 7.3 0.0 0.0096 5.7 55 88 .. 497 530 .. 491 539 .. 0.88 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.3 TPR_BSK1_C 55 akdfktaiecytqfid 70 + df +aiecy + ++ FUN_000336-T1 57 QSDFPKAIECYEKSLN 72 579********99876 PP == domain 2 score: 3.2 bits; conditional E-value: 0.18 TPR_BSK1_C 55 akdfktaiecytqfida 71 + df +aiecy + ++ FUN_000336-T1 97 KSDFPKAIECYEKSLNI 113 459********998875 PP == domain 3 score: 3.3 bits; conditional E-value: 0.18 TPR_BSK1_C 55 akdfktaiecytqfida 71 + df +aiecy + ++ FUN_000336-T1 137 QSDFPKAIECYEKSLNI 153 569********998875 PP == domain 4 score: 0.6 bits; conditional E-value: 1.2 TPR_BSK1_C 55 akdfktaiecytqfidagt 73 + df +aie+y + ++ + FUN_000336-T1 177 QSDFPKAIESYEKSLNIAR 195 579********99887655 PP == domain 5 score: 3.6 bits; conditional E-value: 0.14 TPR_BSK1_C 55 akdfktaiecytqfidagt 73 + df +aiecy + ++ + FUN_000336-T1 217 QSDFPKAIECYEKSLNIAR 235 579********99988765 PP == domain 6 score: -1.4 bits; conditional E-value: 5 TPR_BSK1_C 55 akdfktaiecytqfid 70 + df +aiec + ++ FUN_000336-T1 257 QSDFLKAIECHEKSLN 272 579*******988776 PP == domain 7 score: 3.7 bits; conditional E-value: 0.13 TPR_BSK1_C 55 akdfktaiecytqfidagtmv 75 + df +aiecy + ++ + + FUN_000336-T1 297 QSDFPKAIECYEKSLNIAREA 317 579*********999876655 PP == domain 8 score: -1.0 bits; conditional E-value: 3.6 TPR_BSK1_C 55 akdfktaiecytqfid 70 + df +aiec + ++ FUN_000336-T1 337 QSDFPKAIECHEKSLN 352 579*******988776 PP == domain 9 score: 3.2 bits; conditional E-value: 0.18 TPR_BSK1_C 55 akdfktaiecytqfidag 72 + df +aiecy + ++ FUN_000336-T1 377 QSDFPKAIECYEKSLNIA 394 579********9988765 PP == domain 10 score: 2.6 bits; conditional E-value: 0.28 TPR_BSK1_C 55 akdfktaiecytqfida 71 + df +aiecy + ++ FUN_000336-T1 417 QSDFPKAIECYEKSLNI 433 579********998765 PP == domain 11 score: 2.9 bits; conditional E-value: 0.23 TPR_BSK1_C 55 akdfktaiecytqfida 71 + df +aiecy + ++ FUN_000336-T1 457 QSDFPKAIECYEKSLNI 473 579********998775 PP == domain 12 score: 7.3 bits; conditional E-value: 0.0096 TPR_BSK1_C 55 akdfktaiecytqfidagtmvsptvyarrslsyl 88 + df +aiecy + ++ + + +rr+ y+ FUN_000336-T1 497 QSDFPKAIECYEKSLNIAREAGDQAAVRRASHYV 530 579****************999999999998776 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.14 86 14 30 .. 57 73 .. 56 76 .. 0.87 2 ? 3.7 0.0 0.1 62 15 32 .. 98 115 .. 96 120 .. 0.85 3 ? 4.3 0.0 0.069 41 14 32 .. 137 155 .. 136 160 .. 0.85 4 ? 6.7 0.0 0.012 7.3 14 32 .. 177 195 .. 176 200 .. 0.86 5 ? 4.3 0.0 0.069 41 14 32 .. 217 235 .. 216 240 .. 0.85 6 ? 4.5 0.0 0.058 34 14 33 .. 297 316 .. 296 321 .. 0.83 7 ? -0.7 0.0 2.5 1.5e+03 15 30 .. 338 353 .. 336 358 .. 0.74 8 ? 4.2 0.0 0.072 43 14 32 .. 377 395 .. 376 399 .. 0.84 9 ? 4.2 0.0 0.072 43 14 32 .. 417 435 .. 416 439 .. 0.84 10 ? 4.3 0.0 0.069 41 14 32 .. 457 475 .. 456 480 .. 0.85 11 ? 4.3 0.0 0.067 40 14 32 .. 497 515 .. 496 520 .. 0.84 12 ? -2.1 0.1 6.9 4.1e+03 1 9 [. 531 539 .. 531 539 .. 0.89 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.14 SHNi-TPR 14 nenFeqAvkDlrkaLeL 30 ++ F+ A++ ++k+L++ FUN_000336-T1 57 QSDFPKAIECYEKSLNI 73 5679999999****998 PP == domain 2 score: 3.7 bits; conditional E-value: 0.1 SHNi-TPR 15 enFeqAvkDlrkaLeLre 32 + F+ A++ ++k+L++ + FUN_000336-T1 98 SDFPKAIECYEKSLNIAR 115 5699***********965 PP == domain 3 score: 4.3 bits; conditional E-value: 0.069 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 137 QSDFPKAIECYEKSLNIAR 155 5679************965 PP == domain 4 score: 6.7 bits; conditional E-value: 0.012 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 177 QSDFPKAIESYEKSLNIAR 195 577*************965 PP == domain 5 score: 4.3 bits; conditional E-value: 0.069 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 217 QSDFPKAIECYEKSLNIAR 235 5679************965 PP == domain 6 score: 4.5 bits; conditional E-value: 0.058 SHNi-TPR 14 nenFeqAvkDlrkaLeLree 33 ++ F+ A++ ++k+L++ +e FUN_000336-T1 297 QSDFPKAIECYEKSLNIARE 316 5679************9665 PP == domain 7 score: -0.7 bits; conditional E-value: 2.5 SHNi-TPR 15 enFeqAvkDlrkaLeL 30 + F+ A++ +k+L++ FUN_000336-T1 338 SDFPKAIECHEKSLNI 353 5688888888888888 PP == domain 8 score: 4.2 bits; conditional E-value: 0.072 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 377 QSDFPKAIECYEKSLNIAR 395 5679************955 PP == domain 9 score: 4.2 bits; conditional E-value: 0.072 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 417 QSDFPKAIECYEKSLNIAR 435 5679************955 PP == domain 10 score: 4.3 bits; conditional E-value: 0.069 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 457 QSDFPKAIECYEKSLNIAR 475 5679************965 PP == domain 11 score: 4.3 bits; conditional E-value: 0.067 SHNi-TPR 14 nenFeqAvkDlrkaLeLre 32 ++ F+ A++ ++k+L++ + FUN_000336-T1 497 QSDFPKAIECYEKSLNIAR 515 5679************965 PP == domain 12 score: -2.1 bits; conditional E-value: 6.9 SHNi-TPR 1 AdvydlLGE 9 A++y LG+ FUN_000336-T1 531 AECYLGLGN 539 9***99996 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.39 2.3e+02 3 29 .. 46 72 .. 45 81 .. 0.87 2 ? 1.1 0.0 2.2 1.3e+03 4 29 .. 87 112 .. 84 122 .. 0.82 3 ? 1.5 0.0 1.7 1e+03 7 29 .. 130 152 .. 129 160 .. 0.84 4 ? 1.0 0.0 2.5 1.5e+03 3 28 .. 166 191 .. 164 201 .. 0.85 5 ? 2.0 0.0 1.2 7.2e+02 7 29 .. 210 232 .. 209 242 .. 0.85 6 ? 3.2 0.0 0.48 2.8e+02 4 29 .. 287 312 .. 285 321 .. 0.87 7 ? 4.7 0.0 0.16 94 4 29 .. 367 392 .. 365 403 .. 0.87 8 ? 0.2 0.0 4.5 2.7e+03 9 28 .. 412 431 .. 409 439 .. 0.80 9 ? 4.9 0.0 0.14 82 2 29 .. 445 472 .. 444 480 .. 0.88 10 ? 3.7 0.0 0.33 2e+02 3 29 .. 486 512 .. 484 527 .. 0.81 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.39 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+l l+ a+ + d+ +A+e++e+ l FUN_000336-T1 46 AYLNLGIAYDSQSDFPKAIECYEKSLN 72 6889999****************9876 PP == domain 2 score: 1.1 bits; conditional E-value: 2.2 TPR_14 4 wlalarallalGdpdeAlellerala 29 + l+ a+ d+ +A+e++e+ l FUN_000336-T1 87 YFNLGVAYNSKSDFPKAIECYEKSLN 112 6678889999999*********9875 PP == domain 3 score: 1.5 bits; conditional E-value: 1.7 TPR_14 7 larallalGdpdeAlellerala 29 l+ a+ + d+ +A+e++e+ l FUN_000336-T1 130 LGVAYKSQSDFPKAIECYEKSLN 152 567899999**********9775 PP == domain 4 score: 1.0 bits; conditional E-value: 2.5 TPR_14 3 awlalarallalGdpdeAlelleral 28 +++ l+ a+ + d+ +A+e +e+ l FUN_000336-T1 166 VYYNLGVAYDSQSDFPKAIESYEKSL 191 68889999************999977 PP == domain 5 score: 2.0 bits; conditional E-value: 1.2 TPR_14 7 larallalGdpdeAlellerala 29 l+ a+ + d+ +A+e++e+ l FUN_000336-T1 210 LGVAYNSQSDFPKAIECYEKSLN 232 677999999**********9875 PP == domain 6 score: 3.2 bits; conditional E-value: 0.48 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ l+ a+ + d+ +A+e++e+ l FUN_000336-T1 287 YYDLGVAYDSQSDFPKAIECYEKSLN 312 789999****************9875 PP == domain 7 score: 4.7 bits; conditional E-value: 0.16 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ l+ a+ + d+ +A+e++e+ l FUN_000336-T1 367 YYDLGVAYNSQSDFPKAIECYEKSLN 392 78999*****************9875 PP == domain 8 score: 0.2 bits; conditional E-value: 4.5 TPR_14 9 rallalGdpdeAlelleral 28 ++ + d+ +A+e++e+ l FUN_000336-T1 412 VTYKSQSDFPKAIECYEKSL 431 567888899*******9977 PP == domain 9 score: 4.9 bits; conditional E-value: 0.14 TPR_14 2 eawlalarallalGdpdeAlellerala 29 ++++ l+ a+ + d+ +A+e++e+ l FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIECYEKSLN 472 578999******************9875 PP == domain 10 score: 3.7 bits; conditional E-value: 0.33 TPR_14 3 awlalarallalGdpdeAlellerala 29 +++ l+ a+ + d+ +A+e++e+ l FUN_000336-T1 486 VYYNLGVAYDSQSDFPKAIECYEKSLN 512 6889999****************9876 PP >> TP6A_N Type IIB DNA topoisomerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.1 6.5e+02 36 58 .. 134 156 .. 129 157 .. 0.92 2 ! 10.2 0.1 0.0012 0.74 27 58 .. 165 196 .. 164 197 .. 0.96 3 ? -0.7 0.0 3.2 1.9e+03 36 58 .. 214 236 .. 212 237 .. 0.90 4 ? -1.7 0.0 6.6 3.9e+03 36 58 .. 254 276 .. 252 277 .. 0.85 5 ? 4.4 0.1 0.079 47 28 58 .. 286 316 .. 285 317 .. 0.95 6 ? -1.3 0.0 4.7 2.8e+03 36 58 .. 334 356 .. 332 357 .. 0.87 7 ? 3.5 0.0 0.16 93 28 58 .. 366 396 .. 365 397 .. 0.94 8 ? 1.9 0.0 0.49 2.9e+02 35 58 .. 413 436 .. 407 437 .. 0.92 9 ? 5.9 0.0 0.028 17 27 58 .. 445 476 .. 444 477 .. 0.96 10 ! 7.9 0.1 0.0065 3.9 27 58 .. 485 516 .. 484 517 .. 0.96 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.1 TP6A_N 36 FksQsevdrliddieallgvpRe 58 +ksQs+ ++i+ e+ l++ Re FUN_000336-T1 134 YKSQSDFPKAIECYEKSLNIARE 156 89******************998 PP == domain 2 score: 10.2 bits; conditional E-value: 0.0012 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+YY+ ++sQs+ ++i++ e+ l++ Re FUN_000336-T1 165 DVYYNLGVAYDSQSDFPKAIESYEKSLNIARE 196 89*****************************8 PP == domain 3 score: -0.7 bits; conditional E-value: 3.2 TP6A_N 36 FksQsevdrliddieallgvpRe 58 + sQs+ ++i+ e+ l++ Re FUN_000336-T1 214 YNSQSDFPKAIECYEKSLNIARE 236 78999999***********9998 PP == domain 4 score: -1.7 bits; conditional E-value: 6.6 TP6A_N 36 FksQsevdrliddieallgvpRe 58 + sQs+ ++i+ e+ l++ Re FUN_000336-T1 254 YNSQSDFLKAIECHEKSLNIARE 276 78899999999999999999998 PP == domain 5 score: 4.4 bits; conditional E-value: 0.079 TP6A_N 28 iYYrdvelFksQsevdrliddieallgvpRe 58 +YY ++sQs+ ++i+ e+ l++ Re FUN_000336-T1 286 VYYDLGVAYDSQSDFPKAIECYEKSLNIARE 316 7999999**********************98 PP == domain 6 score: -1.3 bits; conditional E-value: 4.7 TP6A_N 36 FksQsevdrliddieallgvpRe 58 + sQs+ ++i+ e+ l++ Re FUN_000336-T1 334 YNSQSDFPKAIECHEKSLNIARE 356 78999999999999999999998 PP == domain 7 score: 3.5 bits; conditional E-value: 0.16 TP6A_N 28 iYYrdvelFksQsevdrliddieallgvpRe 58 +YY + sQs+ ++i+ e+ l++ Re FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSLNIARE 396 79999999*********************98 PP == domain 8 score: 1.9 bits; conditional E-value: 0.49 TP6A_N 35 lFksQsevdrliddieallgvpRe 58 ++ksQs+ ++i+ e+ l++ Re FUN_000336-T1 413 TYKSQSDFPKAIECYEKSLNIARE 436 79*******************998 PP == domain 9 score: 5.9 bits; conditional E-value: 0.028 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+YY + sQs+ ++i+ e+ l++ Re FUN_000336-T1 445 DVYYGLGVAYNSQSDFPKAIECYEKSLNIARE 476 89****************************98 PP == domain 10 score: 7.9 bits; conditional E-value: 0.0065 TP6A_N 27 diYYrdvelFksQsevdrliddieallgvpRe 58 d+YY+ ++sQs+ ++i+ e+ l++ Re FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEKSLNIARE 516 89****************************98 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.034 20 56 150 .. 50 153 .. 45 161 .. 0.66 2 ? 6.4 0.0 0.018 11 56 151 .. 90 194 .. 79 201 .. 0.69 3 ! 9.2 0.0 0.0023 1.4 55 152 .. 129 235 .. 119 241 .. 0.79 4 ! 7.9 0.0 0.006 3.6 56 150 .. 170 273 .. 163 281 .. 0.75 5 ! 8.3 0.0 0.0047 2.8 54 151 .. 248 354 .. 239 361 .. 0.82 6 ! 9.3 0.0 0.0022 1.3 53 152 .. 327 435 .. 319 441 .. 0.81 7 ! 7.3 0.0 0.0093 5.5 56 150 .. 370 473 .. 363 481 .. 0.76 8 ? 5.1 0.0 0.043 25 56 148 .. 410 511 .. 401 521 .. 0.55 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.034 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteikls...YaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s++d +Ai+ +ek+l++a + + + Y ++ + ++++d kA e ++k l+ + +++ +a+ l++ + +q d+++Ai+ FUN_000336-T1 50 LGIAYDSQSDFPKAIECYEKSLNIAGEAGDRDWEkdvYFNLGVAYNSKSDFPKAIECYEKSLNiareagDRHREGTAYCNLGVAYKSQSDFPKAIE 145 555566677777788888888888766555433222377777777777777777777777664222222456677788888888888888888888 PP TPR_CcmH_CycH 143 aWqkmlkl 150 ++k l++ FUN_000336-T1 146 CYEKSLNI 153 88887765 PP == domain 2 score: 6.4 bits; conditional E-value: 0.018 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteik...lsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s +d +Ai+ +ek+l++a + + + Y ++ + ++++d kA e ++k l+ + + +++ l++ + +q d+++Ai+ FUN_000336-T1 90 LGVAYNSKSDFPKAIECYEKSLNIAREAGDRHregTAYCNLGVAYKSQSDFPKAIECYEKSLNiareagDRDCEKDVYYNLGVAYDSQSDFPKAIE 185 666777778888888888888888876554432227788888888888888888888887765221111222356788888888888888888888 PP TPR_CcmH_CycH 143 aWqkmlkll 151 ++k l++ FUN_000336-T1 186 SYEKSLNIA 194 888877765 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0023 TPR_CcmH_CycH 55 lLGriglslndaetAiqAfekAlklapnnteikls...YaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAi 141 LG + s++d +Ai+ +ek+l++a + + + Y ++ + ++++d kA e ++k l+ + +t+ ra+ l++ + +q d+++Ai FUN_000336-T1 129 NLGVAYKSQSDFPKAIECYEKSLNIAREAGDRDCEkdvYYNLGVAYDSQSDFPKAIESYEKSLNiareagDRHTEGRAYCSLGVAYNSQSDFPKAI 224 68888889999999999999999999887665543333889999999999999999988887753333336789999******************* PP TPR_CcmH_CycH 142 aaWqkmlkllp 152 + ++k l++ FUN_000336-T1 225 ECYEKSLNIAR 235 ***99888765 PP == domain 4 score: 7.9 bits; conditional E-value: 0.006 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteikl...sYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s++d +Ai+++ek+l++a + + + Y + + ++++d kA e ++k l+ + +t+ ra+ l++ + +q d+ +Ai+ FUN_000336-T1 170 LGVAYDSQSDFPKAIESYEKSLNIAREAGDRHTegrAYCSLGVAYNSQSDFPKAIECYEKSLNiareagDRHTEGRAYCSLGVAYNSQSDFLKAIE 265 566666788888999999999999888776665222588888999999999999888888775333333567888899999999999999999998 PP TPR_CcmH_CycH 143 aWqkmlkl 150 +k l++ FUN_000336-T1 266 CHEKSLNI 273 88877765 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0047 TPR_CcmH_CycH 54 llLGriglslndaetAiqAfekAlklapnnte...iklsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeA 140 LG + s++d +Ai+ ek+l++a + + k+ Y ++ + ++++d kA e ++k l+ +++t+ ra+ l++ + +q d+++A FUN_000336-T1 248 CSLGVAYNSQSDFLKAIECHEKSLNIAREAGDrdcEKIVYYDLGVAYDSQSDFPKAIECYEKSLNiareagDQHTEGRAYCSLGVAYNSQSDFPKA 343 56888899999999***********99876551125899*****************999998875444444789999******************* PP TPR_CcmH_CycH 141 iaaWqkmlkll 151 i+ +k l++ FUN_000336-T1 344 IECHEKSLNIA 354 **999988765 PP == domain 6 score: 9.3 bits; conditional E-value: 0.0022 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlklapnnte...iklsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyee 139 LG + s++d +Ai+ ek+l++a + + k+ Y ++ + ++++d kA e ++k l+ + +++ ra+ l++++ +q d+++ FUN_000336-T1 327 YCSLGVAYNSQSDFPKAIECHEKSLNIAREAGDrdcEKIVYYDLGVAYNSQSDFPKAIECYEKSLNiareagDRRREGRAYCNLGVTYKSQSDFPK 422 567899999999***************9876551125899******************999998763322224567889***************** PP TPR_CcmH_CycH 140 AiaaWqkmlkllp 152 Ai+ ++k l++ FUN_000336-T1 423 AIECYEKSLNIAR 435 *****99888755 PP == domain 7 score: 7.3 bits; conditional E-value: 0.0093 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteik...lsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s++d +Ai+ +ek+l++a + + + Y ++ ++ ++++d kA e ++k l+ + + + +++ l++ + +q d+++Ai+ FUN_000336-T1 370 LGVAYNSQSDFPKAIECYEKSLNIAREAGDRRregRAYCNLGVTYKSQSDFPKAIECYEKSLNiareagDRNGEKDVYYGLGVAYNSQSDFPKAIE 465 677778888999999999999999988777662224699999999999999999998888775222222334567899999999999999999999 PP TPR_CcmH_CycH 143 aWqkmlkl 150 ++k l++ FUN_000336-T1 466 CYEKSLNI 473 99988776 PP == domain 8 score: 5.1 bits; conditional E-value: 0.043 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnte...iklsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s++d +Ai+ +ek+l++a + + k Y + + ++++d kA e ++k l+ + + +++ l++ + +q d+++Ai+ FUN_000336-T1 410 LGVTYKSQSDFPKAIECYEKSLNIAREAGDrngEKDVYYGLGVAYNSQSDFPKAIECYEKSLNiareagDRDCEKDVYYNLGVAYDSQSDFPKAIE 505 566666666777777777777777655433000334455555666666666666666655554111111122234566666666666666666666 PP TPR_CcmH_CycH 143 aWqkml 148 ++k l FUN_000336-T1 506 CYEKSL 511 666655 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.065 38 97 142 .. 24 70 .. 19 76 .. 0.65 2 ! 8.4 0.0 0.0017 1 86 142 .. 53 110 .. 46 117 .. 0.86 3 ! 12.9 2.3 7.1e-05 0.042 87 250 .. 134 309 .. 110 313 .. 0.64 4 ! 6.2 0.1 0.0078 4.7 91 142 .. 338 390 .. 310 398 .. 0.63 5 ! 8.5 0.0 0.0016 0.95 205 250 .. 424 469 .. 413 474 .. 0.82 6 ! 6.4 0.1 0.0069 4.1 101 142 .. 468 510 .. 466 517 .. 0.68 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.065 TPR_IF140-IFT172 97 sgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 +k +k l++a+k dr + +y n +++ d+ +ai+ yeks FUN_000336-T1 24 LDKHEKQLKIATKAgDRAGVGLAYLNLGIAYDSQSDFPKAIECYEKS 70 45666666666543367777777777777777777777777777776 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0017 TPR_IF140-IFT172 86 rydllnklyqasgkwdkaleva.ekkdrihlrktyynyakhleakgdieeaiklyeks 142 yd +++ +a + ++k+l++a e dr ++ y+n ++k d+ +ai+ yeks FUN_000336-T1 53 AYDSQSDFPKAIECYEKSLNIAgEAGDRDWEKDVYFNLGVAYNSKSDFPKAIECYEKS 110 5888888999999999999999445699999999999999999999999999999998 PP == domain 3 score: 12.9 bits; conditional E-value: 7.1e-05 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaLesyvkkskdkelkkWwaq 178 y +++ +a + ++k+l++a++ dr ++ yyn +++ d+ +ai+ yeks e + ++ v+ + + ++ k FUN_000336-T1 134 YKSQSDFPKAIECYEKSLNIAREAgDRDCEKDVYYNLGVAYDSQSDFPKAIESYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFPKAIEC 226 444455556666677778888654499999**************************9776666666666666555544555566666666666 PP TPR_IF140-IFT172 179 ylestgeletalkyyeaaedylslv...........rvlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 y s + +a + + + y sl + C+ + l+ a+e + +k y l+ y+++ ++ +ai+ + + FUN_000336-T1 227 YEKSLNIAREAGDRHTEGRAYCSLGvaynsqsdflkAIECHEKSLNIAREAGDRDCEKIVYYDLGVAYDSQSDFPKAIECYEK 309 65555555555555555555555540000000111134455555555555555555667899999999999999999999977 PP == domain 4 score: 6.2 bits; conditional E-value: 0.0078 TPR_IF140-IFT172 91 nklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 +++ +a + +k+l++a++ dr + yy+ +++ d+ +ai+ yeks FUN_000336-T1 338 SDFPKAIECHEKSLNIAREAgDRDCEKIVYYDLGVAYNSQSDFPKAIECYEKS 390 44444444455555555443367677777777777777777777777777776 PP == domain 5 score: 8.5 bits; conditional E-value: 0.0016 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 + Cy + l+ a+e + g+k y l+ y+++ ++ +ai+ + + FUN_000336-T1 424 IECYEKSLNIAREAGDRNGEKDVYYGLGVAYNSQSDFPKAIECYEK 469 6799999999999999999999999999999999999999988876 PP == domain 6 score: 6.4 bits; conditional E-value: 0.0069 TPR_IF140-IFT172 101 dkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 +k+l++a++ dr ++ yyn +++ d+ +ai+ yeks FUN_000336-T1 468 EKSLNIAREAgDRDCEKDVYYNLGVAYDSQSDFPKAIECYEKS 510 5666666543377777777777777777777777777777776 PP >> DUF7971 Family of unknown function (DUF7971) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 1.2 7.2e+02 23 50 .. 56 83 .. 53 88 .. 0.84 2 ? 2.5 0.0 0.4 2.4e+02 23 52 .. 96 125 .. 92 130 .. 0.86 3 ? 2.0 0.0 0.55 3.3e+02 23 50 .. 136 163 .. 131 172 .. 0.86 4 ? 2.9 0.0 0.29 1.8e+02 22 50 .. 175 203 .. 171 213 .. 0.85 5 ? 1.8 0.0 0.66 3.9e+02 23 50 .. 216 243 .. 211 250 .. 0.85 6 ? 0.0 0.0 2.3 1.4e+03 23 51 .. 256 284 .. 251 289 .. 0.85 7 ? 2.6 0.0 0.36 2.2e+02 22 51 .. 295 324 .. 291 330 .. 0.86 8 ? 0.3 0.0 1.8 1.1e+03 23 51 .. 336 364 .. 331 369 .. 0.86 9 ? 1.5 0.0 0.77 4.6e+02 23 50 .. 376 403 .. 372 409 .. 0.85 10 ? 1.5 0.0 0.8 4.7e+02 23 50 .. 416 443 .. 412 448 .. 0.85 11 ? 2.0 0.0 0.56 3.3e+02 23 50 .. 456 483 .. 453 492 .. 0.85 12 ? 2.0 0.0 0.55 3.3e+02 22 48 .. 495 521 .. 490 534 .. 0.77 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.2 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d + e FUN_000336-T1 56 SQSDFPKAIECYEKSLNIAGEAGDRDWE 83 68899************99988887765 PP == domain 2 score: 2.5 bits; conditional E-value: 0.4 DUF7971 23 aaadmqraveglerrlneaieeaddeeeaa 52 +++d+ +a+e +e++ln a e+ d ++e + FUN_000336-T1 96 SKSDFPKAIECYEKSLNIAREAGDRHREGT 125 68999**************99999888765 PP == domain 3 score: 2.0 bits; conditional E-value: 0.55 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d + e FUN_000336-T1 136 SQSDFPKAIECYEKSLNIAREAGDRDCE 163 67899************99999888766 PP == domain 4 score: 2.9 bits; conditional E-value: 0.29 DUF7971 22 eaaadmqraveglerrlneaieeaddeee 50 ++++d+ +a+e++e++ln a e+ d ++e FUN_000336-T1 175 DSQSDFPKAIESYEKSLNIAREAGDRHTE 203 568899*************9999888776 PP == domain 5 score: 1.8 bits; conditional E-value: 0.66 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d ++e FUN_000336-T1 216 SQSDFPKAIECYEKSLNIAREAGDRHTE 243 68899************99999887776 PP == domain 6 score: 0.0 bits; conditional E-value: 2.3 DUF7971 23 aaadmqraveglerrlneaieeaddeeea 51 +++d+ +a+e +e++ln a e+ d + e+ FUN_000336-T1 256 SQSDFLKAIECHEKSLNIAREAGDRDCEK 284 678999***********999999888765 PP == domain 7 score: 2.6 bits; conditional E-value: 0.36 DUF7971 22 eaaadmqraveglerrlneaieeaddeeea 51 ++++d+ +a+e +e++ln a e+ d+++e FUN_000336-T1 295 DSQSDFPKAIECYEKSLNIAREAGDQHTEG 324 568899**************9999988775 PP == domain 8 score: 0.3 bits; conditional E-value: 1.8 DUF7971 23 aaadmqraveglerrlneaieeaddeeea 51 +++d+ +a+e +e++ln a e+ d + e+ FUN_000336-T1 336 SQSDFPKAIECHEKSLNIAREAGDRDCEK 364 678999************99999888765 PP == domain 9 score: 1.5 bits; conditional E-value: 0.77 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d +e FUN_000336-T1 376 SQSDFPKAIECYEKSLNIAREAGDRRRE 403 67899************99998887766 PP == domain 10 score: 1.5 bits; conditional E-value: 0.8 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d + e FUN_000336-T1 416 SQSDFPKAIECYEKSLNIAREAGDRNGE 443 67899************99998887765 PP == domain 11 score: 2.0 bits; conditional E-value: 0.56 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d + e FUN_000336-T1 456 SQSDFPKAIECYEKSLNIAREAGDRDCE 483 67899************99999888766 PP == domain 12 score: 2.0 bits; conditional E-value: 0.55 DUF7971 22 eaaadmqraveglerrlneaieeadde 48 ++++d+ +a+e +e++ln a e+ d+ FUN_000336-T1 495 DSQSDFPKAIECYEKSLNIAREAGDQA 521 568899************998876653 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.97 5.8e+02 59 104 .. 29 74 .. 20 78 .. 0.82 2 ? 5.0 0.0 0.041 24 40 101 .. 48 111 .. 42 114 .. 0.87 3 ? 4.4 0.0 0.061 36 43 101 .. 91 151 .. 88 155 .. 0.83 4 ? 6.8 0.0 0.012 7 42 101 .. 170 231 .. 163 235 .. 0.89 5 ! 7.1 0.0 0.0092 5.5 41 101 .. 289 351 .. 255 355 .. 0.83 6 ? 3.9 0.0 0.09 53 42 101 .. 370 431 .. 361 435 .. 0.84 7 ? 3.4 0.0 0.12 73 43 101 .. 411 471 .. 402 477 .. 0.81 8 ? 3.6 0.0 0.11 65 42 101 .. 450 511 .. 441 515 .. 0.84 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.97 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekakdls 104 ++l++a++ ++a + +lg + +++++ a ec+ek+ ++ FUN_000336-T1 29 KQLKIATKAGDRAGVGLAYLNLGIAYDSQSDFPKAIECYEKSLNIA 74 5778888888888888889999999999999999999999987766 PP == domain 2 score: 5.0 bits; conditional E-value: 0.041 TPR_COPA_B 40 eaLevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 L ++ d++ F a++ ++l++a e +++ +++ + +lg + +k+++ a ec+ek+ FUN_000336-T1 48 LNLGIAYDSQSDFPKAIECyeKSLNIAGEAGDRDWEKDVYFNLGVAYNSKSDFPKAIECYEKSL 111 56889999999999999974467999***9999999*************************975 PP == domain 3 score: 4.4 bits; conditional E-value: 0.061 TPR_COPA_B 43 evstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 v+ +++ F a++ ++l++a+e +++++ + + +lg + +++++ a ec+ek+ FUN_000336-T1 91 GVAYNSKSDFPKAIECyeKSLNIAREAGDRHREGTAYCNLGVAYKSQSDFPKAIECYEKSL 151 56677777777777753367999999999999999***********************985 PP == domain 4 score: 6.8 bits; conditional E-value: 0.012 TPR_COPA_B 42 LevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 L v+ d++ F a++ ++l++a+e +++ + + + +lg + +++++ a ec+ek+ FUN_000336-T1 170 LGVAYDSQSDFPKAIESyeKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFPKAIECYEKSL 231 78999999999999986336799****999999**************************985 PP == domain 5 score: 7.1 bits; conditional E-value: 0.0092 TPR_COPA_B 41 aLevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 L v+ d++ F a++ ++l++a+e +++ + + + +lg + +++++ a ec ek+ FUN_000336-T1 289 DLGVAYDSQSDFPKAIECyeKSLNIAREAGDQHTEGRAYCSLGVAYNSQSDFPKAIECHEKSL 351 68999********9999744679***********************************99975 PP == domain 6 score: 3.9 bits; conditional E-value: 0.09 TPR_COPA_B 42 LevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 L v+ +++ F a++ ++l++a+e ++ ++ + + +lg + +++++ a ec+ek+ FUN_000336-T1 370 LGVAYNSQSDFPKAIECyeKSLNIAREAGDRRREGRAYCNLGVTYKSQSDFPKAIECYEKSL 431 667777778888888763367999999999999999**********************9985 PP == domain 7 score: 3.4 bits; conditional E-value: 0.12 TPR_COPA_B 43 evstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 v+ ++ F a++ ++l++a+e +++ +++ + lg + +++++ a ec+ek+ FUN_000336-T1 411 GVTYKSQSDFPKAIECyeKSLNIAREAGDRNGEKDVYYGLGVAYNSQSDFPKAIECYEKSL 471 56666666666676653367999999999999999**********************9985 PP == domain 8 score: 3.6 bits; conditional E-value: 0.11 TPR_COPA_B 42 LevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 L v+ +++ F a++ ++l++a+e +++ +++ + +lg + +++++ a ec+ek+ FUN_000336-T1 450 LGVAYNSQSDFPKAIECyeKSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPKAIECYEKSL 511 6677777777888877633679999999999999999*********************9985 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.68 4e+02 13 74 .. 19 80 .. 15 84 .. 0.83 2 ? 2.3 0.0 0.41 2.4e+02 14 74 .. 60 120 .. 56 122 .. 0.70 3 ! 7.9 0.0 0.0077 4.6 10 76 .. 96 162 .. 87 171 .. 0.91 4 ? 2.0 0.0 0.52 3.1e+02 54 75 .. 180 201 .. 164 206 .. 0.85 5 ? 4.7 0.2 0.073 44 11 76 .. 217 282 .. 211 292 .. 0.76 6 ? 4.8 0.1 0.069 41 12 76 .. 298 362 .. 287 373 .. 0.74 7 ? 3.2 0.1 0.22 1.3e+02 56 76 .. 342 362 .. 327 408 .. 0.62 8 ? 6.3 0.0 0.024 14 10 75 .. 376 441 .. 367 444 .. 0.90 9 ? 6.9 0.2 0.016 9.5 16 84 .. 462 530 .. 453 534 .. 0.69 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.68 ANAPC5 13 dYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 ++q+ald+ + ++++ ++ a lnl i + + ++ +A++ e + ++A e +D FUN_000336-T1 19 SFQEALDKHEKQLKIATKAGDRAGVGLAYLNLGIAYDSQSDFPKAIECYEKSLNIAGEAGDR 80 57777777777777788888888888999999999999999999999999999999999885 PP == domain 2 score: 2.3 bits; conditional E-value: 0.41 ANAPC5 14 YqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +++a+++ + ++ + ++ + +nl + + + ++ +A++ e + ++Are +D FUN_000336-T1 60 FPKAIECYEKSLNIAGEAGDRDWEKDVYFNLGVAYNSKSDFPKAIECYEKSLNIAREAGDR 120 55555555555555555555555555567777777777888899999**********9996 PP == domain 3 score: 7.9 bits; conditional E-value: 0.0077 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 +++d+++a+++ + ++ + ++ + +a nl + + + ++ +A++ e + ++Are +D c FUN_000336-T1 96 SKSDFPKAIECYEKSLNIAREAGDRHREGTAYCNLGVAYKSQSDFPKAIECYEKSLNIAREAGDRDC 162 678999999999999999999999999999**********************************988 PP == domain 4 score: 2.0 bits; conditional E-value: 0.52 ANAPC5 54 neeAvkaieeaiklArenkDta 75 +A+++ e + ++Are +D FUN_000336-T1 180 FPKAIESYEKSLNIAREAGDRH 201 5689999************976 PP == domain 5 score: 4.7 bits; conditional E-value: 0.073 ANAPC5 11 akdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 ++d+++a+++ + ++ + ++ + a +l + + + ++ +A++ e + ++Are +D c FUN_000336-T1 217 QSDFPKAIECYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFLKAIECHEKSLNIAREAGDRDC 282 567777777777777777777777777777777777777778888999999999999999999888 PP == domain 6 score: 4.8 bits; conditional E-value: 0.069 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 +d+++a+++ + ++ + ++ + a +l + + + ++ +A++ e + ++Are +D c FUN_000336-T1 298 SDFPKAIECYEKSLNIAREAGDQHTEGRAYCSLGVAYNSQSDFPKAIECHEKSLNIAREAGDRDC 362 56667777777777776666666666666677777777777778888888899999999998887 PP == domain 7 score: 3.2 bits; conditional E-value: 0.22 ANAPC5 56 eAvkaieeaiklArenkDtac 76 +A++ e + ++Are +D c FUN_000336-T1 342 KAIECHEKSLNIAREAGDRDC 362 455555556666666666555 PP == domain 8 score: 6.3 bits; conditional E-value: 0.024 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 +++d+++a+++ + ++ + ++++ a nl + + + ++ +A++ e + ++Are +D + FUN_000336-T1 376 SQSDFPKAIECYEKSLNIAREAGDRRREGRAYCNLGVTYKSQSDFPKAIECYEKSLNIAREAGDRN 441 6789999999999999999999999999999999****************************9975 PP == domain 9 score: 6.9 bits; conditional E-value: 0.016 ANAPC5 16 saldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtacLnlalswl 84 +a+++ + ++ + ++ + + nl + + + ++ +A++ e + ++Are +D+a + a +++ FUN_000336-T1 462 KAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPKAIECYEKSLNIAREAGDQAAVRRASHYV 530 5555555555555555555555555556666666666778899999999*********99999888876 PP >> Cohesin_load Cohesin loading factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0029 1.7 151 211 .. 174 236 .. 166 243 .. 0.87 2 ? 4.5 0.0 0.021 13 358 430 .. 247 314 .. 227 333 .. 0.71 3 ! 5.8 0.0 0.0085 5.1 150 210 .. 293 355 .. 284 366 .. 0.86 4 ! 11.5 0.0 0.00016 0.094 293 430 .. 360 514 .. 358 534 .. 0.80 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0029 Cohesin_load 151 e.ssrdysaalenLqsiselaeqrgdqavyvvallleallhl.rssksdsleevqralaaars 211 s++d+ +a+e++++ +++a+ gd+++ a+ + + +++ +s+ ++++e ++ l+ ar FUN_000336-T1 174 YdSQSDFPKAIESYEKSLNIAREAGDRHTEGRAYCSLGVAYNsQSDFPKAIECYEKSLNIARE 236 44567*************************************999999999988888888875 PP == domain 2 score: 4.5 bits; conditional E-value: 0.021 Cohesin_load 358 ylliylaflalvrsdwtkasesl.eelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspllsl 430 y+ l+ ++ ++sd+ ka e+ ++l+ + + ++ + ++++y g+ + ++ d +A ++y+++l+ FUN_000336-T1 247 YC--SLGVAYNSQSDFLKAIECHeKSLNIAREAGDR----DCEKIVYYDLGVAYDSQSDFPKAIECYEKSLNIA 314 44..36667778999999988885666555555554....5599999999999999999999999998888665 PP == domain 3 score: 5.8 bits; conditional E-value: 0.0085 Cohesin_load 150 qe.ssrdysaalenLqsiselaeqrgdqavyvvallleallhl.rssksdsleevqralaaar 210 + s++d+ +a+e +++ +++a+ gdq++ a+ + + +++ +s+ ++++e ++ l+ ar FUN_000336-T1 293 AYdSQSDFPKAIECYEKSLNIAREAGDQHTEGRAYCSLGVAYNsQSDFPKAIECHEKSLNIAR 355 455678*************************************99999999998888888777 PP == domain 4 score: 11.5 bits; conditional E-value: 0.00016 Cohesin_load 293 edlkiLvYlLsgvaylpknsddkkaekfleealklleklkkslk...epslslseasakaewlkvlrcylliylaf..................la 367 +d+ +vY+ gvay + + ka+++ e+ l++ ++ ++++ + ++ ++++++++ k ++cy + + + ++ FUN_000336-T1 360 RDCEKIVYYDLGVAYNSQSDFP-KAIECYEKSLNIAREAGDRRRegrAYCNLGVTYKSQSDFPKAIECYEKSLNIAreagdrngekdvyyglgvAY 454 5677778888888888888776.9999999999999999999888865555556788999999999999998888889999999999999999999 PP Cohesin_load 368 lvrsdwtkasesl.eelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspllsl 430 ++sd+ ka e+ ++l+ + + ++ + + ++y g+ + ++ d +A ++y+++l+ FUN_000336-T1 455 NSQSDFPKAIECYeKSLNIAREAGDRDC----EKDVYYNLGVAYDSQSDFPKAIECYEKSLNIA 514 9999999999998667766666666666....77788999999999999999999999888665 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.035 21 130 162 .. 45 77 .. 21 106 .. 0.84 2 ? 1.4 0.0 0.6 3.6e+02 135 161 .. 90 116 .. 80 121 .. 0.87 3 ? 3.0 0.0 0.19 1.1e+02 130 161 .. 125 156 .. 120 160 .. 0.88 4 ? 4.3 0.1 0.073 44 126 161 .. 160 196 .. 155 200 .. 0.82 5 ? 5.9 0.0 0.024 14 129 161 .. 204 236 .. 199 242 .. 0.89 6 ? 0.9 0.0 0.85 5.1e+02 129 160 .. 244 275 .. 239 278 .. 0.88 7 ? 4.1 0.0 0.089 53 126 161 .. 280 316 .. 277 322 .. 0.81 8 ? 1.5 0.0 0.53 3.2e+02 129 160 .. 324 355 .. 319 358 .. 0.88 9 ? 3.1 0.1 0.18 1.1e+02 126 161 .. 360 396 .. 356 400 .. 0.80 10 ? 5.1 0.0 0.042 25 129 161 .. 404 436 .. 398 448 .. 0.89 11 ? 1.5 0.0 0.56 3.3e+02 135 161 .. 450 476 .. 443 480 .. 0.86 12 ? 5.9 0.1 0.025 15 126 165 .. 480 520 .. 476 532 .. 0.79 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.035 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklskes 162 Ay lG+ +++++ + +A+e+Yek+ ++++e+ FUN_000336-T1 45 LAYLNLGIAYDSQSDFPKAIECYEKSLNIAGEA 77 68899********************99987765 PP == domain 2 score: 1.4 bits; conditional E-value: 0.6 ARM_TT21_C 135 lGliaekeqsykdAaenYekAWklske 161 lG+ +++++ + +A+e+Yek+ +++ e FUN_000336-T1 90 LGVAYNSKSDFPKAIECYEKSLNIARE 116 89999***************9887765 PP == domain 3 score: 3.0 bits; conditional E-value: 0.19 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklske 161 Ay lG+ + +++ + +A+e+Yek+ +++ e FUN_000336-T1 125 TAYCNLGVAYKSQSDFPKAIECYEKSLNIARE 156 588899*******************9887765 PP == domain 4 score: 4.3 bits; conditional E-value: 0.073 ARM_TT21_C 126 kscakA.yellGliaekeqsykdAaenYekAWklske 161 ++c k y lG+ +++++ + +A+e+Yek+ +++ e FUN_000336-T1 160 RDCEKDvYYNLGVAYDSQSDFPKAIESYEKSLNIARE 196 67877525669*******************9887765 PP == domain 5 score: 5.9 bits; conditional E-value: 0.024 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklske 161 ++Ay lG+ +++++ + +A+e+Yek+ +++ e FUN_000336-T1 204 GRAYCSLGVAYNSQSDFPKAIECYEKSLNIARE 236 699***********************9887765 PP == domain 6 score: 0.9 bits; conditional E-value: 0.85 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklsk 160 ++Ay lG+ +++++ + +A+e+ ek+ +++ FUN_000336-T1 244 GRAYCSLGVAYNSQSDFLKAIECHEKSLNIAR 275 689**********************9877765 PP == domain 7 score: 4.1 bits; conditional E-value: 0.089 ARM_TT21_C 126 kscakA.yellGliaekeqsykdAaenYekAWklske 161 ++c k y lG+ +++++ + +A+e+Yek+ +++ e FUN_000336-T1 280 RDCEKIvYYDLGVAYDSQSDFPKAIECYEKSLNIARE 316 66777514459*******************9887765 PP == domain 8 score: 1.5 bits; conditional E-value: 0.53 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklsk 160 ++Ay lG+ +++++ + +A+e+ ek+ +++ FUN_000336-T1 324 GRAYCSLGVAYNSQSDFPKAIECHEKSLNIAR 355 699**********************9877765 PP == domain 9 score: 3.1 bits; conditional E-value: 0.18 ARM_TT21_C 126 kscakA.yellGliaekeqsykdAaenYekAWklske 161 ++c k y lG+ +++++ + +A+e+Yek+ +++ e FUN_000336-T1 360 RDCEKIvYYDLGVAYNSQSDFPKAIECYEKSLNIARE 396 66777514459*******************9887765 PP == domain 10 score: 5.1 bits; conditional E-value: 0.042 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklske 161 ++Ay lG+ + +++ + +A+e+Yek+ +++ e FUN_000336-T1 404 GRAYCNLGVTYKSQSDFPKAIECYEKSLNIARE 436 699***********************9888766 PP == domain 11 score: 1.5 bits; conditional E-value: 0.56 ARM_TT21_C 135 lGliaekeqsykdAaenYekAWklske 161 lG+ +++++ + +A+e+Yek+ +++ e FUN_000336-T1 450 LGVAYNSQSDFPKAIECYEKSLNIARE 476 89999***************9887665 PP == domain 12 score: 5.9 bits; conditional E-value: 0.025 ARM_TT21_C 126 kscakA.yellGliaekeqsykdAaenYekAWklskesspa 165 ++c k y lG+ +++++ + +A+e+Yek+ +++ e+ + FUN_000336-T1 480 RDCEKDvYYNLGVAYDSQSDFPKAIECYEKSLNIAREAGDQ 520 67877525669*******************99998877655 PP >> CoV_NSP8 Coronavirus replicase NSP8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.8 4.7e+02 30 52 .. 59 81 .. 46 87 .. 0.82 2 ? 2.2 0.0 0.35 2.1e+02 31 53 .. 99 122 .. 83 128 .. 0.81 3 ? 4.3 0.0 0.076 45 25 53 .. 133 162 .. 124 167 .. 0.80 4 ? 2.7 0.0 0.24 1.4e+02 31 52 .. 179 201 .. 164 206 .. 0.80 5 ? 1.9 0.0 0.41 2.5e+02 31 52 .. 219 241 .. 205 245 .. 0.80 6 ? 0.3 0.0 1.3 7.8e+02 32 53 .. 261 282 .. 244 286 .. 0.79 7 ? -0.3 0.0 2.1 1.2e+03 30 49 .. 299 318 .. 287 323 .. 0.76 8 ? 1.5 0.0 0.56 3.3e+02 31 53 .. 339 362 .. 325 366 .. 0.81 9 ? 1.8 0.0 0.45 2.7e+02 31 52 .. 378 401 .. 366 406 .. 0.79 10 ? 2.2 0.0 0.35 2.1e+02 28 52 .. 416 441 .. 403 446 .. 0.80 11 ? 3.4 0.0 0.15 88 30 53 .. 459 482 .. 451 490 .. 0.82 12 ? 1.3 0.0 0.66 3.9e+02 31 57 .. 499 525 .. 484 535 .. 0.73 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.8 CoV_NSP8 30 sseqllkqlkkalniaksefdrd 52 + ++ ++ ++k+lnia + drd FUN_000336-T1 59 DFPKAIECYEKSLNIAGEAGDRD 81 3488999*********9999998 PP == domain 2 score: 2.2 bits; conditional E-value: 0.35 CoV_NSP8 31 s.eqllkqlkkalniaksefdrda 53 ++ ++ ++k+lnia+ + dr + FUN_000336-T1 99 DfPKAIECYEKSLNIAREAGDRHR 122 248999***********9999975 PP == domain 3 score: 4.3 bits; conditional E-value: 0.076 CoV_NSP8 25 akangss.eqllkqlkkalniaksefdrda 53 a +++s ++ ++ ++k+lnia+ + drd FUN_000336-T1 133 AYKSQSDfPKAIECYEKSLNIAREAGDRDC 162 55555555999****************995 PP == domain 4 score: 2.7 bits; conditional E-value: 0.24 CoV_NSP8 31 s.eqllkqlkkalniaksefdrd 52 ++ ++ ++k+lnia+ + dr FUN_000336-T1 179 DfPKAIESYEKSLNIAREAGDRH 201 34899************999986 PP == domain 5 score: 1.9 bits; conditional E-value: 0.41 CoV_NSP8 31 s.eqllkqlkkalniaksefdrd 52 ++ ++ ++k+lnia+ + dr FUN_000336-T1 219 DfPKAIECYEKSLNIAREAGDRH 241 258999***********999986 PP == domain 6 score: 0.3 bits; conditional E-value: 1.3 CoV_NSP8 32 eqllkqlkkalniaksefdrda 53 + ++ +k+lnia+ + drd FUN_000336-T1 261 LKAIECHEKSLNIAREAGDRDC 282 45677889***********995 PP == domain 7 score: -0.3 bits; conditional E-value: 2.1 CoV_NSP8 30 sseqllkqlkkalniaksef 49 + ++ ++ ++k+lnia+ + FUN_000336-T1 299 DFPKAIECYEKSLNIAREAG 318 3388999*********9765 PP == domain 8 score: 1.5 bits; conditional E-value: 0.56 CoV_NSP8 31 s.eqllkqlkkalniaksefdrda 53 ++ ++ +k+lnia+ + drd FUN_000336-T1 339 DfPKAIECHEKSLNIAREAGDRDC 362 24889999*************995 PP == domain 9 score: 1.8 bits; conditional E-value: 0.45 CoV_NSP8 31 s..eqllkqlkkalniaksefdrd 52 s ++ ++ ++k+lnia+ + dr FUN_000336-T1 378 SdfPKAIECYEKSLNIAREAGDRR 401 325899************998885 PP == domain 10 score: 2.2 bits; conditional E-value: 0.35 CoV_NSP8 28 ngss.eqllkqlkkalniaksefdrd 52 ++s ++ ++ ++k+lnia+ + dr+ FUN_000336-T1 416 SQSDfPKAIECYEKSLNIAREAGDRN 441 33334899************999996 PP == domain 11 score: 3.4 bits; conditional E-value: 0.15 CoV_NSP8 30 sseqllkqlkkalniaksefdrda 53 + ++ ++ ++k+lnia+ + drd FUN_000336-T1 459 DFPKAIECYEKSLNIAREAGDRDC 482 338999***************995 PP == domain 12 score: 1.3 bits; conditional E-value: 0.66 CoV_NSP8 31 s.eqllkqlkkalniaksefdrdaavqk 57 ++ ++ ++k+lnia+ + d+ aav++ FUN_000336-T1 499 DfPKAIECYEKSLNIAREAGDQ-AAVRR 525 2488999*********988664.56665 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 2 1.2e+03 132 153 .] 50 71 .. 45 71 .. 0.77 2 ? 2.0 0.0 0.55 3.3e+02 127 153 .] 85 111 .. 74 111 .. 0.83 3 ? 1.8 0.0 0.62 3.7e+02 130 153 .] 128 151 .. 122 151 .. 0.84 4 ? 2.0 0.0 0.54 3.2e+02 130 153 .] 208 231 .. 196 231 .. 0.85 5 ? 4.1 0.0 0.12 70 89 153 .] 243 311 .. 229 311 .. 0.70 6 ? 4.4 0.1 0.094 56 82 153 .] 316 391 .. 281 391 .. 0.55 7 ? 2.0 0.0 0.54 3.2e+02 130 153 .] 408 431 .. 403 431 .. 0.88 8 ? 0.9 0.0 1.1 6.8e+02 132 153 .] 450 471 .. 440 471 .. 0.78 9 ? 1.1 0.0 1 6.1e+02 8 153 .] 453 471 .. 448 479 .. 0.57 10 ? 1.5 0.0 0.74 4.4e+02 127 153 .] 485 511 .. 474 511 .. 0.81 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 2 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s++d+ kai++Y +L FUN_000336-T1 50 LGIAYDSQSDFPKAIECYEKSL 71 5566778999999999998765 PP == domain 2 score: 2.0 bits; conditional E-value: 0.55 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 ++ ++l+ + s++d+ kai++Y +L FUN_000336-T1 85 DVYFNLGVAYNSKSDFPKAIECYEKSL 111 667788889999999999999998776 PP == domain 3 score: 1.8 bits; conditional E-value: 0.62 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 ++l+ + s++d+ kai++Y +L FUN_000336-T1 128 CNLGVAYKSQSDFPKAIECYEKSL 151 677888999999999999998776 PP == domain 4 score: 2.0 bits; conditional E-value: 0.54 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 ++l+ + s++d+ kai++Y +L FUN_000336-T1 208 CSLGVAYNSQSDFPKAIECYEKSL 231 678888999999999999998776 PP == domain 5 score: 4.1 bits; conditional E-value: 0.12 ARM_TT21_4th 89 keealetLkkakelqarvlkrvsveqpdav....eeqkklaakiclqlAehaaserdyekaiklYkeAL 153 + a +L a++ q+ lk +++++++ + + + + + ++l+ + s++d+ kai++Y +L FUN_000336-T1 243 EGRAYCSLGVAYNSQSDFLKAIECHEKSLNiareAGDRDCEKIVYYDLGVAYDSQSDFPKAIECYEKSL 311 5556777888888899999988887776541111223444455668999999*************9876 PP == domain 6 score: 4.4 bits; conditional E-value: 0.094 ARM_TT21_4th 82 kvrksgkkeealetLkkakelqarvlkrvsveqpdav....eeqkklaakiclqlAehaaserdyekaiklYkeAL 153 + ++ + a +L a++ q+ k +++++++ + + + + + ++l+ + s++d+ kai++Y +L FUN_000336-T1 316 EAGDQHTEGRAYCSLGVAYNSQSDFPKAIECHEKSLNiareAGDRDCEKIVYYDLGVAYNSQSDFPKAIECYEKSL 391 3335555666667777777777777777766655543111112233444455678888888888888888887765 PP == domain 7 score: 2.0 bits; conditional E-value: 0.54 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 ++l+ ++ s++d+ kai++Y +L FUN_000336-T1 408 CNLGVTYKSQSDFPKAIECYEKSL 431 67888999************9876 PP == domain 8 score: 0.9 bits; conditional E-value: 1.1 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s++d+ kai++Y +L FUN_000336-T1 450 LGVAYNSQSDFPKAIECYEKSL 471 5667888999999999998765 PP == domain 9 score: 1.1 bits; conditional E-value: 1 ARM_TT21_4th 8 alvktHqYkkAinYYeaalksseqksLrldLAeLllkLkqydkaekvlkqaleeekskdleslmeevklllLlakvrksgkkeealetLkkakelq 103 a FUN_000336-T1 453 A----------------------------------------------------------------------------------------------- 453 4............................................................................................... PP ARM_TT21_4th 104 arvlkrvsveqpdaveeqkklaakiclqlAehaaserdyekaiklYkeAL 153 + s++d+ kai++Y +L FUN_000336-T1 454 --------------------------------YNSQSDFPKAIECYEKSL 471 ................................445555555555555443 PP == domain 10 score: 1.5 bits; conditional E-value: 0.74 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 ++ ++l+ + s++d+ kai++Y +L FUN_000336-T1 485 DVYYNLGVAYDSQSDFPKAIECYEKSL 511 666778888999999999999998776 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.3 0.022 13 14 132 .. 22 143 .. 17 150 .. 0.59 2 ! 7.3 0.2 0.0085 5 20 134 .. 108 225 .. 102 227 .. 0.74 3 ! 7.6 0.1 0.0066 3.9 39 134 .. 167 265 .. 163 288 .. 0.69 4 ? 2.4 0.0 0.26 1.6e+02 38 63 .. 366 391 .. 348 399 .. 0.83 5 ? 3.9 0.0 0.092 54 20 63 .. 388 431 .. 381 439 .. 0.76 6 ? 0.2 0.0 1.2 7.3e+02 39 63 .. 447 471 .. 435 480 .. 0.84 7 ? 2.4 0.1 0.25 1.5e+02 21 63 .. 469 511 .. 462 523 .. 0.76 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.022 RPN7 14 keleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghk...idlllnlirvgiffndwalvskylekaksliekg 106 + l++ e++lk a + + a+++l+ y + d+ +A+++ye+ ++ + +g d+++nl +d+ ++ + ek ++ ++ FUN_000336-T1 22 EALDKHEKQLKIATKAGDRAGVGLAYLNLGIAYDSQSDFPKAIECYEKSLNIAGEAGDRdweKDVYFNLGVAYNSKSDFPKAIECYEKSLNIAREA 117 566666777777777777777778888888888888888888888888666555544431114555554433334444444444445555555555 PP RPN7 107 gdwerrnrlkvyeGlaalairkfkeA 132 gd+ r+ + G+a+ ++ +f +A FUN_000336-T1 118 GDRHREGTAYCNLGVAYKSQSDFPKA 143 55555555555555555555555555 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0085 RPN7 20 eaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghk...idlllnlirvgi.ffndwalvskylekaksliekggdwer 111 e+ l+ a+e + +a+ +l+ y + d+ +A+++ye+ ++ + +g d+++nl v++ +d+ ++ ++ ek ++ ++gd+ + FUN_000336-T1 108 EKSLNIAREAGDRHREGTAYCNLGVAYKSQSDFPKAIECYEKSLNIAREAGDRdceKDVYYNL-GVAYdSQSDFPKAIESYEKSLNIAREAGDRHT 202 5666666666666666788999999999999*********99777666655431115555555.44441456888888888999999999999999 PP RPN7 112 rnrlkvyeGlaalairkfkeAak 134 + r + G+a+ ++ +f +A + FUN_000336-T1 203 EGRAYCSLGVAYNSQSDFPKAIE 225 99999999999999999988866 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0066 RPN7 39 ledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskyle...kaksliekggdwerrnrlkvyeGlaalairkfke 131 +++l+ y + d+ +A+++ye+ ++ + +g + +g+++n + k +e k ++ ++gd+ ++ r + G+a+ ++ +f + FUN_000336-T1 167 YYNLGVAYDSQSDFPKAIESYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFPKAIEcyeKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFLK 262 566777777777777777777777777777777777777777777777755555555541114444555677777777777777777777777777 PP RPN7 132 Aak 134 A + FUN_000336-T1 263 AIE 265 765 PP == domain 4 score: 2.4 bits; conditional E-value: 0.26 RPN7 38 aledlaehyakigdlenAlkayerar 63 ++dl+ y + d+ +A+++ye+ + FUN_000336-T1 366 VYYDLGVAYNSQSDFPKAIECYEKSL 391 478999*****************976 PP == domain 5 score: 3.9 bits; conditional E-value: 0.092 RPN7 20 eaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 e+ l+ a+e ra+ +l+ y + d+ +A+++ye+ + FUN_000336-T1 388 EKSLNIAREAGDRRREGRAYCNLGVTYKSQSDFPKAIECYEKSL 431 55666666666666666889999999999999999999999865 PP == domain 6 score: 0.2 bits; conditional E-value: 1.2 RPN7 39 ledlaehyakigdlenAlkayerar 63 ++ l+ y + d+ +A+++ye+ + FUN_000336-T1 447 YYGLGVAYNSQSDFPKAIECYEKSL 471 566788899999**********976 PP == domain 7 score: 2.4 bits; conditional E-value: 0.25 RPN7 21 aelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 + l+ a+e ++ +++l+ y + d+ +A+++ye+ + FUN_000336-T1 469 KSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPKAIECYEKSL 511 5555555555555557789999******************976 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.5 3e+02 64 112 .. 55 103 .. 52 114 .. 0.86 2 ? 0.4 0.0 1.5 8.6e+02 65 111 .. 96 142 .. 92 153 .. 0.82 3 ? 3.1 0.0 0.22 1.3e+02 68 114 .. 139 185 .. 135 196 .. 0.83 4 ? 3.7 0.0 0.14 84 64 113 .. 175 224 .. 169 234 .. 0.87 5 ? 0.8 0.0 1.1 6.3e+02 67 113 .. 218 264 .. 212 275 .. 0.83 6 ? 4.2 0.0 0.096 57 64 113 .. 295 344 .. 290 356 .. 0.87 7 ? -1.0 0.0 3.9 2.3e+03 68 110 .. 379 421 .. 375 436 .. 0.75 8 ? -0.9 0.0 3.7 2.2e+03 68 110 .. 419 461 .. 415 475 .. 0.75 9 ? 2.4 0.0 0.35 2.1e+02 67 111 .. 458 502 .. 443 509 .. 0.85 10 ? 3.9 0.0 0.12 70 64 111 .. 495 542 .. 491 570 .. 0.82 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.5 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpa 112 Ds+ ++ + e ye ln+a g ++ e+++ +L ay+++ ++ +a FUN_000336-T1 55 DSQSDFPKAIECYEKSLNIAGEAGDRDWEKDVYFNLGVAYNSKSDFPKA 103 899999999*********************9999999999887666655 PP == domain 2 score: 0.4 bits; conditional E-value: 1.5 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykp 111 s+ ++ + e ye ln+a+ g ++ e +a +L ay+++ ++ + FUN_000336-T1 96 SKSDFPKAIECYEKSLNIAREAGDRHREGTAYCNLGVAYKSQSDFPK 142 56777888899************999999999999988877766655 PP == domain 3 score: 3.1 bits; conditional E-value: 0.22 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpaik 114 ++ + e ye ln+a+ g ++ e+++ +L ayd++ ++ +ai+ FUN_000336-T1 139 DFPKAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPKAIE 185 56677899************************999999888877774 PP == domain 4 score: 3.7 bits; conditional E-value: 0.14 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Ds+ ++ + e+ye ln+a+ g ++ e +a L ay+++ ++ +ai FUN_000336-T1 175 DSQSDFPKAIESYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFPKAI 224 99999999***********************9999999998887666655 PP == domain 5 score: 0.8 bits; conditional E-value: 1.1 Ulvan_lyase_2nd 67 rkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 ++ + e ye ln+a+ g ++ e +a L ay+++ ++ +ai FUN_000336-T1 218 SDFPKAIECYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFLKAI 264 566677899*****************999999999998887766665 PP == domain 6 score: 4.2 bits; conditional E-value: 0.096 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Ds+ ++ + e ye ln+a+ g ++ e +a L ay+++ ++ +ai FUN_000336-T1 295 DSQSDFPKAIECYEKSLNIAREAGDQHTEGRAYCSLGVAYNSQSDFPKAI 344 89999999*************************99999999887776666 PP == domain 7 score: -1.0 bits; conditional E-value: 3.9 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgyk 110 ++ + e ye ln+a+ g + e +a +L y+++ ++ FUN_000336-T1 379 DFPKAIECYEKSLNIAREAGDRRREGRAYCNLGVTYKSQSDFP 421 5667778999999999999999888888888877777665555 PP == domain 8 score: -0.9 bits; conditional E-value: 3.7 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgyk 110 ++ + e ye ln+a+ g ++ e+++ L ay+++ ++ FUN_000336-T1 419 DFPKAIECYEKSLNIAREAGDRNGEKDVYYGLGVAYNSQSDFP 461 5566778999999999999999988888877777777665555 PP == domain 9 score: 2.4 bits; conditional E-value: 0.35 Ulvan_lyase_2nd 67 rkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykp 111 ++ + e ye ln+a+ g ++ e+++ +L ayd++ ++ + FUN_000336-T1 458 SDFPKAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPK 502 566778899********************9999999998766655 PP == domain 10 score: 3.9 bits; conditional E-value: 0.12 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykp 111 Ds+ ++ + e ye ln+a+ g ++ ++a ++++ y G+ + FUN_000336-T1 495 DSQSDFPKAIECYEKSLNIAREAGDQAAVRRASHYVAECYLGLGNSVK 542 89999999**************************99999976666554 PP >> Paf67 RNA polymerase I-associated factor PAF67 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 1.9 1.1e+03 164 194 .. 86 116 .. 83 130 .. 0.82 2 ? 2.6 0.0 0.13 78 159 195 .. 161 197 .. 138 211 .. 0.80 3 ? 5.6 0.0 0.016 9.7 136 199 .. 254 321 .. 242 330 .. 0.75 4 ? 3.4 0.0 0.073 43 158 193 .. 360 395 .. 325 417 .. 0.77 5 ? -0.2 0.0 0.92 5.4e+02 164 191 .. 446 473 .. 419 480 .. 0.89 6 ? 3.9 0.0 0.053 32 159 195 .. 481 517 .. 458 531 .. 0.79 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.9 Paf67 164 lyyyvGfaylmlrrYkdAirtfssillyiqr 194 +y+++G+ay + +Ai+++++ l+ + FUN_000336-T1 86 VYFNLGVAYNSKSDFPKAIECYEKSLNIARE 116 6899*******************99976554 PP == domain 2 score: 2.6 bits; conditional E-value: 0.13 Paf67 159 aahvtlyyyvGfaylmlrrYkdAirtfssillyiqrt 195 ++ +yy++G+ay + +Ai+ +++ l+ + FUN_000336-T1 161 DCEKDVYYNLGVAYDSQSDFPKAIESYEKSLNIAREA 197 588899**********************999765554 PP == domain 3 score: 5.6 bits; conditional E-value: 0.016 Paf67 136 YtlAlkvlenidlskkalf....skvpaahvtlyyyvGfaylmlrrYkdAirtfssillyiqrtkqyq 199 Y++ l+ i++++k+l + ++ +yy +G+ay + +Ai+++++ l+ + ++ FUN_000336-T1 254 YNSQSDFLKAIECHEKSLNiareAGDRDCEKIVYYDLGVAYDSQSDFPKAIECYEKSLNIAREAGDQH 321 66666788999999988543333445689999************************998766654454 PP == domain 4 score: 3.4 bits; conditional E-value: 0.073 Paf67 158 paahvtlyyyvGfaylmlrrYkdAirtfssillyiq 193 ++ +yy +G+ay + +Ai+++++ l+ + FUN_000336-T1 360 RDCEKIVYYDLGVAYNSQSDFPKAIECYEKSLNIAR 395 5688889**********************9997654 PP == domain 5 score: -0.2 bits; conditional E-value: 0.92 Paf67 164 lyyyvGfaylmlrrYkdAirtfssilly 191 +yy +G+ay + +Ai+++++ l+ FUN_000336-T1 446 VYYGLGVAYNSQSDFPKAIECYEKSLNI 473 7999******************999875 PP == domain 6 score: 3.9 bits; conditional E-value: 0.053 Paf67 159 aahvtlyyyvGfaylmlrrYkdAirtfssillyiqrt 195 ++ +yy++G+ay + +Ai+++++ l+ + FUN_000336-T1 481 DCEKDVYYNLGVAYDSQSDFPKAIECYEKSLNIAREA 517 588899***********************99765544 PP >> Vault Major Vault Protein repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 1.8 1.1e+03 12 30 .. 102 120 .. 102 121 .. 0.84 2 ? 0.0 0.0 2.1 1.3e+03 12 30 .. 142 160 .. 142 160 .. 0.84 3 ? 1.1 0.0 0.99 5.9e+02 12 30 .. 182 200 .. 182 201 .. 0.90 4 ? 0.2 0.0 1.8 1.1e+03 12 30 .. 222 240 .. 222 241 .. 0.84 5 ? 1.2 0.0 0.94 5.6e+02 11 30 .. 261 280 .. 260 280 .. 0.90 6 ? -1.0 0.0 4.5 2.7e+03 12 30 .. 302 320 .. 302 320 .. 0.82 7 ? -0.8 0.0 3.7 2.2e+03 13 30 .. 343 360 .. 342 360 .. 0.74 8 ? 0.0 0.0 2.1 1.3e+03 12 30 .. 382 400 .. 382 400 .. 0.84 9 ? 0.0 0.0 2.1 1.3e+03 12 30 .. 422 440 .. 422 440 .. 0.84 10 ? 0.0 0.0 2.1 1.3e+03 12 30 .. 462 480 .. 462 480 .. 0.84 11 ? -0.5 0.0 3.1 1.9e+03 12 30 .. 502 520 .. 502 530 .. 0.80 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 1.8 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 102 KAIECYEKSLNIAREAGDR 120 578888888889******8 PP == domain 2 score: 0.0 bits; conditional E-value: 2.1 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 142 KAIECYEKSLNIAREAGDR 160 578888888889******8 PP == domain 3 score: 1.1 bits; conditional E-value: 0.99 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 182 KAIESYEKSLNIAREAGDR 200 68999999999*******8 PP == domain 4 score: 0.2 bits; conditional E-value: 1.8 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 222 KAIECYEKSLNIAREAGDR 240 578888888889******8 PP == domain 5 score: 1.2 bits; conditional E-value: 0.94 Vault 11 LrAledFtDrdgveRkaGee 30 L+A+e + + ++ R+aG++ FUN_000336-T1 261 LKAIECHEKSLNIAREAGDR 280 789999999999*******8 PP == domain 6 score: -1.0 bits; conditional E-value: 4.5 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 302 KAIECYEKSLNIAREAGDQ 320 578888888889*****95 PP == domain 7 score: -0.8 bits; conditional E-value: 3.7 Vault 13 AledFtDrdgveRkaGee 30 A+e + + ++ R+aG++ FUN_000336-T1 343 AIECHEKSLNIAREAGDR 360 566666666799*****8 PP == domain 8 score: 0.0 bits; conditional E-value: 2.1 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 382 KAIECYEKSLNIAREAGDR 400 578888888889******8 PP == domain 9 score: 0.0 bits; conditional E-value: 2.1 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 422 KAIECYEKSLNIAREAGDR 440 578888888889******8 PP == domain 10 score: 0.0 bits; conditional E-value: 2.1 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 462 KAIECYEKSLNIAREAGDR 480 578888888889******8 PP == domain 11 score: -0.5 bits; conditional E-value: 3.1 Vault 12 rAledFtDrdgveRkaGee 30 +A+e ++ + ++ R+aG++ FUN_000336-T1 502 KAIECYEKSLNIAREAGDQ 520 5778888888899****97 PP >> ssDBP Phage single-stranded DNA-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.29 1.7e+02 25 47 .. 49 71 .. 34 83 .. 0.79 2 ? 2.0 0.0 0.47 2.8e+02 26 48 .. 90 112 .. 83 121 .. 0.80 3 ? 3.2 0.0 0.19 1.2e+02 19 48 .. 124 152 .. 115 163 .. 0.77 4 ? 1.2 0.1 0.84 5e+02 27 47 .. 171 191 .. 164 201 .. 0.81 5 ? 3.4 0.0 0.18 1.1e+02 19 48 .. 204 232 .. 196 243 .. 0.78 6 ? 1.7 0.1 0.57 3.4e+02 27 48 .. 291 312 .. 284 322 .. 0.81 7 ? 0.7 0.0 1.2 7e+02 18 46 .. 323 350 .. 315 362 .. 0.75 8 ? 1.8 0.0 0.55 3.2e+02 27 47 .. 371 391 .. 364 401 .. 0.82 9 ? 1.9 0.0 0.51 3e+02 19 48 .. 404 432 .. 395 442 .. 0.78 10 ? 2.6 0.0 0.31 1.9e+02 26 48 .. 450 472 .. 434 484 .. 0.79 11 ? 2.2 0.1 0.4 2.4e+02 27 50 .. 491 514 .. 478 525 .. 0.81 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.29 ssDBP 25 aeafahledapfPqkisyyvesk 47 + + a+ ++ +fP+ i+ y +s FUN_000336-T1 49 NLGIAYDSQSDFPKAIECYEKSL 71 557899*************9984 PP == domain 2 score: 2.0 bits; conditional E-value: 0.47 ssDBP 26 eafahledapfPqkisyyveskd 48 + a+ + +fP+ i+ y +s + FUN_000336-T1 90 LGVAYNSKSDFPKAIECYEKSLN 112 577999************99854 PP == domain 3 score: 3.2 bits; conditional E-value: 0.19 ssDBP 19 GnpYtmaeafahledapfPqkisyyveskd 48 G +Y + + a++++ +fP+ i+ y +s + FUN_000336-T1 124 GTAYC-NLGVAYKSQSDFPKAIECYEKSLN 152 55554.457899*************99955 PP == domain 4 score: 1.2 bits; conditional E-value: 0.84 ssDBP 27 afahledapfPqkisyyvesk 47 + a+ ++ +fP+ i+ y +s FUN_000336-T1 171 GVAYDSQSDFPKAIESYEKSL 191 568999*********999885 PP == domain 5 score: 3.4 bits; conditional E-value: 0.18 ssDBP 19 GnpYtmaeafahledapfPqkisyyveskd 48 G++Y + + a+ ++ +fP+ i+ y +s + FUN_000336-T1 204 GRAYC-SLGVAYNSQSDFPKAIECYEKSLN 232 66665.4578999************99955 PP == domain 6 score: 1.7 bits; conditional E-value: 0.57 ssDBP 27 afahledapfPqkisyyveskd 48 + a+ ++ +fP+ i+ y +s + FUN_000336-T1 291 GVAYDSQSDFPKAIECYEKSLN 312 568999***********99955 PP == domain 7 score: 0.7 bits; conditional E-value: 1.2 ssDBP 18 kGnpYtmaeafahledapfPqkisyyves 46 +G++Y + + a+ ++ +fP+ i+ + +s FUN_000336-T1 323 EGRAYC-SLGVAYNSQSDFPKAIECHEKS 350 466665.45779999*****999877766 PP == domain 8 score: 1.8 bits; conditional E-value: 0.55 ssDBP 27 afahledapfPqkisyyvesk 47 + a+ ++ +fP+ i+ y +s FUN_000336-T1 371 GVAYNSQSDFPKAIECYEKSL 391 56899************9985 PP == domain 9 score: 1.9 bits; conditional E-value: 0.51 ssDBP 19 GnpYtmaeafahledapfPqkisyyveskd 48 G++Y + + ++++ +fP+ i+ y +s + FUN_000336-T1 404 GRAYC-NLGVTYKSQSDFPKAIECYEKSLN 432 56664.4577899************99854 PP == domain 10 score: 2.6 bits; conditional E-value: 0.31 ssDBP 26 eafahledapfPqkisyyveskd 48 + a+ ++ +fP+ i+ y +s + FUN_000336-T1 450 LGVAYNSQSDFPKAIECYEKSLN 472 567999************99955 PP == domain 11 score: 2.2 bits; conditional E-value: 0.4 ssDBP 27 afahledapfPqkisyyveskdev 50 + a+ ++ +fP+ i+ y +s + FUN_000336-T1 491 GVAYDSQSDFPKAIECYEKSLNIA 514 5689999**********9996555 PP >> MTES_1575 REase_MTES_1575 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.95 5.7e+02 21 62 .. 42 84 .. 33 91 .. 0.82 2 ? -0.7 0.0 3.7 2.2e+03 28 61 .. 89 123 .. 83 129 .. 0.78 3 ? 2.1 0.1 0.48 2.9e+02 28 62 .. 129 164 .. 121 171 .. 0.83 4 ? 4.4 0.1 0.097 57 29 62 .. 250 284 .. 240 291 .. 0.85 5 ? -0.7 0.0 3.7 2.2e+03 26 58 .. 287 320 .. 284 327 .. 0.80 6 ? 2.5 0.1 0.37 2.2e+02 29 62 .. 330 364 .. 316 367 .. 0.81 7 ? 1.1 0.0 1 5.9e+02 26 61 .. 367 403 .. 364 407 .. 0.84 8 ? -1.2 0.0 5.4 3.2e+03 28 60 .. 409 442 .. 400 451 .. 0.80 9 ? 1.7 0.1 0.66 3.9e+02 29 62 .. 450 484 .. 436 491 .. 0.83 10 ? -2.0 0.0 9.1 5.4e+03 29 62 .. 490 524 .. 484 526 .. 0.72 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.95 MTES_1575 21 gvggyriDlvvedp.pgryllaiecDgatyhsskeardrdrlr 62 gvg +++l++ + ++++ aiec +++ + + ea drd ++ FUN_000336-T1 42 GVGLAYLNLGIAYDsQSDFPKAIECYEKSLNIAGEAGDRDWEK 84 566667778887776799999**********999999999886 PP == domain 2 score: -0.7 bits; conditional E-value: 3.7 MTES_1575 28 Dlvvedp.pgryllaiecDgatyhsskeardrdrl 61 +l+v + ++++ aiec +++ + ++ea dr r+ FUN_000336-T1 89 NLGVAYNsKSDFPKAIECYEKSLNIAREAGDRHRE 123 56666665688889******999999999888775 PP == domain 3 score: 2.1 bits; conditional E-value: 0.48 MTES_1575 28 Dlvvedp.pgryllaiecDgatyhsskeardrdrlr 62 +l+v + ++++ aiec +++ + ++ea drd+++ FUN_000336-T1 129 NLGVAYKsQSDFPKAIECYEKSLNIAREAGDRDCEK 164 56666665688899*******************987 PP == domain 4 score: 4.4 bits; conditional E-value: 0.097 MTES_1575 29 lvvedp.pgryllaiecDgatyhsskeardrdrlr 62 l+v + ++++l aiec +++ + ++ea drd+++ FUN_000336-T1 250 LGVAYNsQSDFLKAIECHEKSLNIAREAGDRDCEK 284 5566665689999*******************975 PP == domain 5 score: -0.7 bits; conditional E-value: 3.7 MTES_1575 26 riDlvvedp.pgryllaiecDgatyhsskeardr 58 + Dl+v + ++++ aiec +++ + ++ea d+ FUN_000336-T1 287 YYDLGVAYDsQSDFPKAIECYEKSLNIAREAGDQ 320 5699998886799999****99988887777665 PP == domain 6 score: 2.5 bits; conditional E-value: 0.37 MTES_1575 29 lvvedp.pgryllaiecDgatyhsskeardrdrlr 62 l+v + ++++ aiec +++ + ++ea drd+++ FUN_000336-T1 330 LGVAYNsQSDFPKAIECHEKSLNIAREAGDRDCEK 364 5666665688889*******************875 PP == domain 7 score: 1.1 bits; conditional E-value: 1 MTES_1575 26 riDlvvedp.pgryllaiecDgatyhsskeardrdrl 61 + Dl+v + ++++ aiec +++ + ++ea dr r+ FUN_000336-T1 367 YYDLGVAYNsQSDFPKAIECYEKSLNIAREAGDRRRE 403 579999999779999********99999998888765 PP == domain 8 score: -1.2 bits; conditional E-value: 5.4 MTES_1575 28 Dlvvedp.pgryllaiecDgatyhsskeardrdr 60 +l+v+ + ++++ aiec +++ + ++ea dr+ FUN_000336-T1 409 NLGVTYKsQSDFPKAIECYEKSLNIAREAGDRNG 442 66777776688889****9999999999888865 PP == domain 9 score: 1.7 bits; conditional E-value: 0.66 MTES_1575 29 lvvedp.pgryllaiecDgatyhsskeardrdrlr 62 l+v + ++++ aiec +++ + ++ea drd+++ FUN_000336-T1 450 LGVAYNsQSDFPKAIECYEKSLNIAREAGDRDCEK 484 5555554678888*******************987 PP == domain 10 score: -2.0 bits; conditional E-value: 9.1 MTES_1575 29 lvvedp.pgryllaiecDgatyhsskeardrdrlr 62 l+v + ++++ aiec +++ + ++ea d+ r FUN_000336-T1 490 LGVAYDsQSDFPKAIECYEKSLNIAREAGDQAAVR 524 55555546788889999999998888887776655 PP >> Ferritin Ferritin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 6.9 4.1e+03 94 113 .. 102 121 .. 94 128 .. 0.80 2 ? 2.6 0.0 0.29 1.7e+02 94 115 .. 182 203 .. 176 204 .. 0.91 3 ? 0.6 0.0 1.2 6.8e+02 94 115 .. 222 243 .. 216 244 .. 0.90 4 ? 0.7 0.0 1.1 6.3e+02 94 115 .. 302 323 .. 297 324 .. 0.90 5 ? 0.1 0.0 1.7 1e+03 94 124 .. 502 532 .. 498 533 .. 0.84 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 6.9 Ferritin 94 kvtkslrelielaeeegDya 113 k+++ +++ ++a+e+gD + FUN_000336-T1 102 KAIECYEKSLNIAREAGDRH 121 78888999999999999975 PP == domain 2 score: 2.6 bits; conditional E-value: 0.29 Ferritin 94 kvtkslrelielaeeegDyata 115 k+++s+++ ++a+e+gD +t+ FUN_000336-T1 182 KAIESYEKSLNIAREAGDRHTE 203 789****************996 PP == domain 3 score: 0.6 bits; conditional E-value: 1.2 Ferritin 94 kvtkslrelielaeeegDyata 115 k+++ +++ ++a+e+gD +t+ FUN_000336-T1 222 KAIECYEKSLNIAREAGDRHTE 243 78999**************996 PP == domain 4 score: 0.7 bits; conditional E-value: 1.1 Ferritin 94 kvtkslrelielaeeegDyata 115 k+++ +++ ++a+e+gD +t+ FUN_000336-T1 302 KAIECYEKSLNIAREAGDQHTE 323 78999**************996 PP == domain 5 score: 0.1 bits; conditional E-value: 1.7 Ferritin 94 kvtkslrelielaeeegDyatadflewflae 124 k+++ +++ ++a+e+gD a + +++ae FUN_000336-T1 502 KAIECYEKSLNIAREAGDQAAVRRASHYVAE 532 789999************9988777777765 PP >> Clathrin Region in Clathrin and VPS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 2.5 1.5e+03 91 109 .. 52 70 .. 22 79 .. 0.69 2 ? -1.1 0.0 3.3 2e+03 106 124 .. 94 112 .. 88 118 .. 0.68 3 ? 0.3 0.0 1.2 7.3e+02 92 111 .. 133 152 .. 113 180 .. 0.70 4 ? -0.3 0.0 1.9 1.1e+03 92 108 .. 213 229 .. 163 243 .. 0.67 5 ? -0.1 0.0 1.7 1e+03 91 112 .. 292 313 .. 254 326 .. 0.71 6 ? -2.5 0.0 9.3 5.6e+03 92 112 .. 333 351 .. 321 380 .. 0.66 7 ? -0.6 0.0 2.4 1.4e+03 92 122 .. 373 390 .. 349 400 .. 0.64 8 ? 1.4 0.0 0.59 3.5e+02 93 138 .. 414 457 .. 404 462 .. 0.71 9 ? 6.8 0.1 0.013 7.5 80 133 .. 482 536 .. 441 542 .. 0.80 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 2.5 Clathrin 91 ilYkknedwdeaisvlkkn 109 i+Y+ +d+ +ai++++k FUN_000336-T1 52 IAYDSQSDFPKAIECYEKS 70 3788888888888886654 PP == domain 2 score: -1.1 bits; conditional E-value: 3.3 Clathrin 106 lkknklykraieyavkasn 124 +++++++++aie+++k+ n FUN_000336-T1 94 YNSKSDFPKAIECYEKSLN 112 6666777777777776644 PP == domain 3 score: 0.3 bits; conditional E-value: 1.2 Clathrin 92 lYkknedwdeaisvlkknkl 111 +Yk +d+ +ai++++k + FUN_000336-T1 133 AYKSQSDFPKAIECYEKSLN 152 56666777777776555333 PP == domain 4 score: -0.3 bits; conditional E-value: 1.9 Clathrin 92 lYkknedwdeaisvlkk 108 +Y +d+ +ai++++k FUN_000336-T1 213 AYNSQSDFPKAIECYEK 229 44555555555555444 PP == domain 5 score: -0.1 bits; conditional E-value: 1.7 Clathrin 91 ilYkknedwdeaisvlkknkly 112 ++Y+ +d+ +ai++++k ++ FUN_000336-T1 292 VAYDSQSDFPKAIECYEKSLNI 313 3677777888888876665444 PP == domain 6 score: -2.5 bits; conditional E-value: 9.3 Clathrin 92 lYkknedwdeaisv.lkknkly 112 +Y +d+ +ai++ +k+ + FUN_000336-T1 333 AYNSQSDFPKAIEChEKS---L 351 566666777777752322...2 PP == domain 7 score: -0.6 bits; conditional E-value: 2.4 Clathrin 92 lYkknedwdeaisvlkknklykraieyavka 122 +Y +d+ +ai++++k + FUN_000336-T1 373 AYNSQSDFPKAIECYEK-------------S 390 45555555555555444.............3 PP == domain 8 score: 1.4 bits; conditional E-value: 0.59 Clathrin 93 Ykknedwdeaisvlkknklykraieyavkasnpelweellealldn 138 Yk +d+ +ai++++k +++ a e+ + +++++ l+ a++ + FUN_000336-T1 414 YKSQSDFPKAIECYEK--SLNIAREAGDRNGEKDVYYGLGVAYNSQ 457 7777788888887666..6666667777777777777777777766 PP == domain 9 score: 6.8 bits; conditional E-value: 0.013 Clathrin 80 cekaklyeealilYkknedwdeaisvlkknklykrai..eyavkasnpelweelle 133 cek y + ++Y+ +d+ +ai++++k ++ r++ ++av++++ ++e+ l+ FUN_000336-T1 482 CEKDVYY-NLGVAYDSQSDFPKAIECYEKSLNIAREAgdQAAVRRASHYVAECYLG 536 6666666.67789*************999999999999********9999999876 PP >> Piezo_cap Piezo non-specific cation channel, cap domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.37 2.2e+02 265 284 .. 151 170 .. 141 172 .. 0.90 2 ? -1.0 0.0 2.5 1.5e+03 266 284 .. 272 290 .. 269 291 .. 0.89 3 ? -1.0 0.0 2.5 1.5e+03 266 284 .. 352 370 .. 349 371 .. 0.89 4 ? -1.9 0.0 4.6 2.8e+03 265 284 .. 391 410 .. 386 416 .. 0.85 5 ? -1.7 0.0 4.1 2.4e+03 265 284 .. 431 450 .. 426 450 .. 0.88 6 ? 1.7 0.0 0.37 2.2e+02 265 284 .. 471 490 .. 461 492 .. 0.90 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.37 Piezo_cap 265 IylaReegdlelEedlyakL 284 + +aRe+gd + E+d+y++L FUN_000336-T1 151 LNIAREAGDRDCEKDVYYNL 170 679**************988 PP == domain 2 score: -1.0 bits; conditional E-value: 2.5 Piezo_cap 266 ylaReegdlelEedlyakL 284 +aRe+gd + E+ +y+ L FUN_000336-T1 272 NIAREAGDRDCEKIVYYDL 290 69**************977 PP == domain 3 score: -1.0 bits; conditional E-value: 2.5 Piezo_cap 266 ylaReegdlelEedlyakL 284 +aRe+gd + E+ +y+ L FUN_000336-T1 352 NIAREAGDRDCEKIVYYDL 370 69**************977 PP == domain 4 score: -1.9 bits; conditional E-value: 4.6 Piezo_cap 265 IylaReegdlelEedlyakL 284 + +aRe+gd + E + y +L FUN_000336-T1 391 LNIAREAGDRRREGRAYCNL 410 569**************998 PP == domain 5 score: -1.7 bits; conditional E-value: 4.1 Piezo_cap 265 IylaReegdlelEedlyakL 284 + +aRe+gd E+d+y+ L FUN_000336-T1 431 LNIAREAGDRNGEKDVYYGL 450 569*************9865 PP == domain 6 score: 1.7 bits; conditional E-value: 0.37 Piezo_cap 265 IylaReegdlelEedlyakL 284 + +aRe+gd + E+d+y++L FUN_000336-T1 471 LNIAREAGDRDCEKDVYYNL 490 679**************988 PP >> Foie-gras_1 Foie gras liver health family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 5.3 3.1e+03 169 217 .. 63 111 .. 58 118 .. 0.81 2 ? 0.3 0.0 1.1 6.3e+02 161 214 .. 135 188 .. 99 198 .. 0.61 3 ? -1.4 0.0 3.4 2e+03 167 211 .. 221 265 .. 182 279 .. 0.64 4 ? -2.1 0.0 5.6 3.3e+03 169 213 .. 303 347 .. 281 358 .. 0.80 5 ? 0.4 0.0 0.98 5.8e+02 169 218 .. 383 432 .. 375 438 .. 0.88 6 ? 3.9 0.0 0.087 52 168 247 .. 462 541 .. 443 552 .. 0.89 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 5.3 Foie-gras_1 169 iidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrpla 217 +i++++++l + + + + ++ + ++++ +y d+ ka+e ++ FUN_000336-T1 63 AIECYEKSLNIAGEAGDRDWEKDVYFNLGVAYNSKSDFPKAIECYEKSL 111 57888888888888888888899999999************99988665 PP == domain 2 score: 0.3 bits; conditional E-value: 1.1 Foie-gras_1 161 kgvdhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellr 214 k+ + +i++++++l +++ + + ++ + ++++ +y d+ ka+e ++ FUN_000336-T1 135 KSQSDFPKAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPKAIESYE 188 333444456666777766666666666666777777777777777777766665 PP == domain 3 score: -1.4 bits; conditional E-value: 3.4 Foie-gras_1 167 kliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakale 211 +i++++++l +++ + + ++ + ++ +y d+ ka+e FUN_000336-T1 221 PKAIECYEKSLNIAREAGDRHTEGRAYCSLGVAYNSQSDFLKAIE 265 446677777777776666666666666677777777777777766 PP == domain 4 score: -2.1 bits; conditional E-value: 5.6 Foie-gras_1 169 iidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalell 213 +i++++++l +++ + + ++ + ++ +y d+ ka+e FUN_000336-T1 303 AIECYEKSLNIAREAGDQHTEGRAYCSLGVAYNSQSDFPKAIECH 347 688899999988888888888888888899999999999988865 PP == domain 5 score: 0.4 bits; conditional E-value: 0.98 Foie-gras_1 169 iidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplal 218 +i++++++l +++ + +R + + +++ y d+ ka+e ++ + FUN_000336-T1 383 AIECYEKSLNIAREAGDRRREGRAYCNLGVTYKSQSDFPKAIECYEKSLN 432 799****************************************9987655 PP == domain 6 score: 3.9 bits; conditional E-value: 0.087 Foie-gras_1 168 liidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplalsyrqegWwsLleevlwalrecalkvgdvk 247 +i++++++l +++ + + ++ + ++++ +y d+ ka+e ++ ++ r++g + + + + ec+l +g++ FUN_000336-T1 462 KAIECYEKSLNIAREAGDRDCEKDVYYNLGVAYDSQSDFPKAIECYEKSLNIAREAGDQAAVRRASHYVAECYLGLGNSV 541 57999*****99999999999***********************************999999999999999999988765 PP >> RAG1 Recombination-activation protein 1 (RAG1) nonamer-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.12 70 54 66 .. 112 124 .. 106 128 .. 0.87 2 ? -0.8 0.0 4.4 2.6e+03 54 68 .. 152 166 .. 149 168 .. 0.85 3 ? -0.2 0.1 2.9 1.7e+03 54 65 .. 192 203 .. 190 206 .. 0.84 4 ? 0.0 0.0 2.5 1.5e+03 54 65 .. 232 243 .. 229 247 .. 0.84 5 ? -1.5 0.1 7.2 4.3e+03 54 65 .. 312 323 .. 310 326 .. 0.83 6 ? 1.0 0.1 1.2 7.1e+02 54 66 .. 392 404 .. 388 407 .. 0.86 7 ? -0.7 0.0 4.1 2.5e+03 54 68 .. 432 446 .. 429 448 .. 0.85 8 ? -0.8 0.0 4.4 2.6e+03 54 68 .. 472 486 .. 469 488 .. 0.85 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.12 RAG1 54 lllldAGdeaRea 66 ++++AGd++Re FUN_000336-T1 112 NIAREAGDRHREG 124 689********95 PP == domain 2 score: -0.8 bits; conditional E-value: 4.4 RAG1 54 lllldAGdeaReadv 68 ++++AGd+ e dv FUN_000336-T1 152 NIAREAGDRDCEKDV 166 679******999886 PP == domain 3 score: -0.2 bits; conditional E-value: 2.9 RAG1 54 lllldAGdeaRe 65 ++++AGd++ e FUN_000336-T1 192 NIAREAGDRHTE 203 579*******87 PP == domain 4 score: 0.0 bits; conditional E-value: 2.5 RAG1 54 lllldAGdeaRe 65 ++++AGd++ e FUN_000336-T1 232 NIAREAGDRHTE 243 679*******87 PP == domain 5 score: -1.5 bits; conditional E-value: 7.2 RAG1 54 lllldAGdeaRe 65 ++++AGd++ e FUN_000336-T1 312 NIAREAGDQHTE 323 579******976 PP == domain 6 score: 1.0 bits; conditional E-value: 1.2 RAG1 54 lllldAGdeaRea 66 ++++AGd+ Re FUN_000336-T1 392 NIAREAGDRRREG 404 689********85 PP == domain 7 score: -0.7 bits; conditional E-value: 4.1 RAG1 54 lllldAGdeaReadv 68 ++++AGd+ e dv FUN_000336-T1 432 NIAREAGDRNGEKDV 446 679******999886 PP == domain 8 score: -0.8 bits; conditional E-value: 4.4 RAG1 54 lllldAGdeaReadv 68 ++++AGd+ e dv FUN_000336-T1 472 NIAREAGDRDCEKDV 486 679******999886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (603 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 351 (0.0137405); expected 510.9 (0.02) Passed bias filter: 315 (0.0123312); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 46 (0.00180074); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 43 [number of targets reported over threshold] # CPU time: 0.53u 0.41s 00:00:00.94 Elapsed: 00:00:00.47 # Mc/sec: 5190.98 // Query: FUN_000337-T1 [L=798] Description: FUN_000337 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-17 63.1 2.6 1.4e-16 61.2 2.6 2.0 1 COR-A C-terminal of Roc, COR-A domain 5e-15 56.3 0.4 4.3e-06 27.4 0.0 3.2 3 Roc Ras of Complex, Roc, domain of DAPkinase 5.7e-05 23.2 0.0 0.19 11.7 0.0 2.6 2 Ras Ras family ------ inclusion threshold ------ 0.029 14.6 0.0 0.062 13.6 0.0 1.5 1 PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.098 12.5 0.0 2.4 8.0 0.0 2.9 3 Gtr1_RagA Gtr1/RagA G protein conserved region Domain annotation for each model (and alignments): >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.2 2.6 2.7e-20 1.4e-16 1 142 [] 417 577 .. 417 577 .. 0.89 Alignments for each domain: == domain 1 score: 61.2 bits; conditional E-value: 2.7e-20 COR-A 1 Pkswlevreelee.kkseknyisleeyreicke.nglkeeeeqdrllkfLhdlGvllyfqddeelkdlviLkpeWlteavykvlds.......... 84 P +wl+++++l+ ++ ++ i++e+ ++i++e +++++++e ++l+fLhd l++f+d el++lv+L+p+Wl+++ +v++ FUN_000337-T1 417 PIKWLKYEKALQViLAEGHKWITIEHAKRIASEvCQIHDDQEFITVLDFLHDQRILIHFDDTVELNKLVVLDPQWLIDVFKTVITVkrydkqergf 512 89***********99999************98658**************************99**********************98888887777 PP COR-A 85 ...kevlkkkGllkeedlkkiwkek.ypaeehdellrlmekfelcyelek...eeedtylvpqlL 142 l+++G+l+e+ l++ w++ ++++ ++l+ +mekf l + ++ ++tylvp++L FUN_000337-T1 513 kdlWLKLEREGILEEKLLRHAWSSIvEEQHTFESLIAIMEKFSLLCSWSSadePCSKTYLVPSML 577 4332234567**************878888889***********9999887665579*****987 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 4e-09 2e-05 2 70 .. 24 79 .. 23 125 .. 0.72 2 ! 27.4 0.0 8.4e-10 4.3e-06 44 91 .. 228 273 .. 199 298 .. 0.72 3 ? -2.0 0.0 1.2 5.9e+03 59 84 .. 625 650 .. 621 658 .. 0.79 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 4e-09 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfr 70 ++l+G+++ GKtsl k + +f+++e+st+g+d + + k++ +iW t+ +++ FUN_000337-T1 24 IMLIGQERSGKTSLKKSLQGLQFNPNEDSTVGIDADPSYF-------------KVTTEIWKTGKKDQAA 79 89********************************987654.............2445566666555544 PP == domain 2 score: 27.4 bits; conditional E-value: 8.4e-10 Roc 44 ikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.srs 91 ++++ ++ i +WD+aG+ ++++h+l+++++a+++lv+d sr+ FUN_000337-T1 228 VDKM---ESEDGIYSVLWDFAGESVYYETHQLFLTSRAIYLLVYDlSRD 273 2233...3334466789****************************7553 PP == domain 3 score: -2.0 bits; conditional E-value: 1.2 Roc 59 niWDtaGqerfrslhplyyreaaaai 84 ++W ta + +++ +++y e + + FUN_000337-T1 625 EFWSTANPQLYKNFARFYTAEDENFS 650 689**************998766544 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 0.0 3.8e-05 0.19 2 45 .. 24 67 .. 23 83 .. 0.86 2 ! 8.7 0.0 0.00032 1.6 47 83 .. 236 272 .. 207 298 .. 0.80 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3.8e-05 Ras 2 lvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdg 45 ++l+G++ GK+sl + +F+ + +sT+g+d + ++v FUN_000337-T1 24 IMLIGQERSGKTSLKKSLQGLQFNPNEDSTVGIDADPSYFKVTT 67 689*******************************8777666654 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00032 Ras 47 evklqiwDTAGqerfralreayyrgaegillvydits 83 + +wD AG + + +++++++ + llvyd+++ FUN_000337-T1 236 GIYSVLWDFAGESVYYETHQLFLTSRAIYLLVYDLSR 272 455679****************************976 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 1.2e-05 0.062 4 27 .. 24 47 .. 20 59 .. 0.87 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.2e-05 PduV-EutP 4 illiGkvgsGKttLtqalkgeelk 27 i+liG+ sGKt+L+++l+g++++ FUN_000337-T1 24 IMLIGQERSGKTSLKKSLQGLQFN 47 9******************98875 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.0 0.00047 2.4 2 18 .. 24 40 .. 23 80 .. 0.82 2 ? -0.4 0.0 0.18 9e+02 24 65 .. 213 254 .. 209 270 .. 0.76 3 ? -0.6 0.0 0.2 1e+03 166 197 .. 531 564 .. 498 568 .. 0.70 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00047 Gtr1_RagA 2 vLLmGksksGKsSirsv 18 ++L+G+++sGK+S+++ FUN_000337-T1 24 IMLIGQERSGKTSLKKS 40 89************985 PP == domain 2 score: -0.4 bits; conditional E-value: 0.18 Gtr1_RagA 24 spkdtlrlgatidveksevrflgnltlnlwdlgGqekfldey 65 +p+++ +l + + +++++ + ++ lwd+ G + + ++ FUN_000337-T1 213 MPEEIETLIKELRDKVDKMESEDGIYSVLWDFAGESVYYETH 254 5677777777777778888999999999******99998874 PP == domain 3 score: -0.6 bits; conditional E-value: 0.2 Gtr1_RagA 166 ykAfskivqkLi..pnlevleelLkklassseae 197 +A+s+iv++ +l ++ e+++ l+s s+a+ FUN_000337-T1 531 RHAWSSIVEEQHtfESLIAIMEKFSLLCSWSSAD 564 37******76431156666667777777766666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (798 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1206 (0.0472108); expected 510.9 (0.02) Passed bias filter: 730 (0.028577); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.40u 0.41s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7513.78 // Query: FUN_000338-T1 [L=188] Description: FUN_000338 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-05 23.0 0.0 0.00021 21.8 0.0 1.7 1 Death Death domain Domain annotation for each model (and alignments): >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 8.4e-09 0.00021 11 81 .. 123 187 .. 113 188 .] 0.87 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 8.4e-09 Death 11 veplgkdWreLarklglseeeideiesenrdlrsqtyelLklWearegknatvgnLleaLrklgrrdaaek 81 ++ g++W+ +a++lgl+ ei+++ + r ++ + L +r + +v++L+++L+++g+ +a++ FUN_000338-T1 123 LSG-GEEWKVVAERLGLNAKEIRYLDVRM---RNPCDAALSVVSQR--RCMNVDDLYDVLTECGMPVLADI 187 566.89**********************9...**************..7777************9988776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 617 (0.0241535); expected 510.9 (0.02) Passed bias filter: 579 (0.0226659); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1898.41 // Query: FUN_000339-T1 [L=551] Description: FUN_000339 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-45 152.6 3.8 4.5e-13 49.7 0.0 4.8 6 TPR_12 Tetratricopeptide repeat 5.2e-24 83.5 5.6 3.9e-06 26.9 0.0 6.5 6 TPR_1 Tetratricopeptide repeat 2.5e-18 65.1 10.9 2.7e-05 24.4 0.0 6.9 7 TPR_2 Tetratricopeptide repeat 2.5e-15 55.7 0.0 0.0029 18.0 0.0 5.0 4 TPR_7 Tetratricopeptide repeat 3.3e-14 53.6 0.1 2.9e-06 28.0 0.0 2.4 2 Roc Ras of Complex, Roc, domain of DAPkinase 4.2e-13 48.8 11.9 0.00088 19.7 0.1 6.6 6 TPR_8 Tetratricopeptide repeat 8.3e-10 38.8 0.0 0.016 15.6 0.0 4.4 4 TPR_10 Tetratricopeptide repeat 1.8e-07 31.6 0.0 0.029 14.9 0.0 3.7 3 ANAPC5 Anaphase-promoting complex subunit 5 3.8e-07 30.4 0.0 7.1e-07 29.5 0.0 1.3 1 SNAP Soluble NSF attachment protein, SNAP 2.4e-06 28.4 0.5 0.55 11.2 0.0 4.9 5 TPR_16 Tetratricopeptide repeat 1e-05 26.3 0.0 2.6 9.4 0.0 5.8 5 TPR_6 Tetratricopeptide repeat 1.2e-05 26.0 0.7 7.9 8.0 0.0 5.4 5 TPR_14 Tetratricopeptide repeat 4.3e-05 23.9 0.0 11 7.1 0.0 5.4 5 TPR_17 Tetratricopeptide repeat 7.9e-05 22.8 0.0 0.53 10.3 0.0 2.3 2 Ras Ras family 0.00015 22.0 0.1 0.45 10.7 0.0 3.0 2 RPN7 26S proteasome subunit RPN7 0.00051 20.1 10.7 9.1 6.6 0.0 7.4 8 TPR_11 TPR repeat 0.0012 18.8 0.0 0.45 10.5 0.0 4.1 4 SHNi-TPR SHNi-TPR 0.0071 16.1 0.0 0.099 12.4 0.0 2.0 2 TPR_MalT MalT-like TPR region 0.0075 16.8 0.1 4.5 7.9 0.0 2.8 2 TPR_9 Tetratricopeptide repeat ------ inclusion threshold ------ 0.01 16.2 0.0 3.8 7.8 0.0 3.8 4 DUF7380 Domain of unknown function (DUF7380) 0.029 14.0 0.2 0.045 13.4 0.2 1.3 1 G-alpha G-protein alpha subunit 0.031 14.6 0.0 0.067 13.5 0.0 1.5 1 PduV-EutP Ethanolamine utilisation - propanediol util 0.034 14.7 0.5 11 6.7 0.0 4.1 4 MIT MIT (microtubule interacting and transport) 0.062 13.7 0.0 25 5.3 0.0 3.3 3 Cdc6_lid Cdc6 AAA+ ATPase-type lid domain 0.064 13.1 0.0 2.2 8.1 0.0 2.2 2 Gtr1_RagA Gtr1/RagA G protein conserved region 0.07 13.9 0.0 17 6.2 0.0 3.3 3 NRBF2_MIT MIT domain of nuclear receptor-binding fact 0.096 11.8 0.1 3.4 6.7 0.0 2.7 2 TPR_IF140-IFT172 IF140/IFT172 TPR domain 0.1 13.1 0.0 15 6.1 0.0 3.2 4 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain 0.12 13.2 0.1 19 6.3 0.0 3.1 2 PPR PPR repeat 0.17 11.8 0.1 0.31 11.0 0.1 1.4 1 Arf ADP-ribosylation factor family 0.23 11.9 0.0 4.9 7.6 0.0 2.9 3 ssDBP Phage single-stranded DNA-binding protein Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.1 5.8e-06 0.0047 25 77 .] 28 78 .. 27 78 .. 0.96 2 ! 40.2 0.0 4.9e-13 4.1e-10 18 77 .] 61 118 .. 59 118 .. 0.96 3 ! 42.8 0.0 7.6e-14 6.2e-11 5 76 .. 88 157 .. 84 158 .. 0.93 4 ! 49.7 0.0 5.5e-16 4.5e-13 5 76 .. 128 197 .. 124 198 .. 0.95 5 ! 30.8 0.0 4.1e-10 3.4e-07 4 67 .. 167 228 .. 164 229 .. 0.96 6 ? -0.7 0.0 2.8 2.3e+03 63 72 .. 256 265 .. 253 266 .. 0.63 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 5.8e-06 TPR_12 25 llekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ek l++a ++++p + + a+ Lg++y ++ +A++ +e++l+ia++ FUN_000339-T1 28 HHEKHLNIAGEAHNPAR--EGDAHLSLGIAYDSHSNFPKAIKGYEKSLNIARE 78 89************999..999****************************986 PP == domain 2 score: 40.2 bits; conditional E-value: 4.9e-13 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ +A++ +ek+l++a+++ +d+ + a+ nL ++y gd+ +A+e++e++l+ia++ FUN_000339-T1 61 NFPKAIKGYEKSLNIAREA--GDRAREGDAYLNLLIAYKSIGDFPKAIECFEKSLDIARE 118 7899***************..9999********************************986 PP == domain 3 score: 42.8 bits; conditional E-value: 7.6e-14 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl ++ g++ +A+e++ek+l++a+++ +d+ + a+ nLg++y+ g + e +e +e++l+ia+ FUN_000339-T1 88 AYLNLLIAYKSIGDFPKAIECFEKSLDIAREA--GDRAKEGDAYLNLGTAYEFHGGFSEGIESYEKSLDIAR 157 566777788899********************..99**********************************98 PP == domain 4 score: 49.7 bits; conditional E-value: 5.5e-16 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ ++ g + e +e +ek+l++a+r+ +d+ + a+ nLg++++ gd+ +A+e++e++l+ia FUN_000339-T1 128 AYLNLGTAYEFHGGFSEGIESYEKSLDIARRV--GDRTSEGDAYLNLGIAHQSHGDFPKAIECFEESLNIAS 197 899*****************************..88999******************************985 PP == domain 5 score: 30.8 bits; conditional E-value: 4.1e-10 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlel 67 a++nl+ +++ g++ +A+e++e++l++a+++ +d+ + ++a + L + y+algd+ +A+e+ FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEESLNIASEA--GDWAGISRAKQYLRISYFALGDFLKAVEY 228 5899***************************99..9*************************987 PP == domain 6 score: -0.7 bits; conditional E-value: 2.8 TPR_12 63 eAlelleqal 72 +A+e++++al FUN_000339-T1 256 KAREAYNKAL 265 5666666666 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 3.2e-05 0.026 2 31 .. 47 76 .. 46 78 .. 0.92 2 ! 19.6 0.1 9.6e-07 0.00079 3 31 .. 88 116 .. 86 118 .. 0.85 3 ! 12.0 0.0 0.00025 0.21 2 31 .. 127 156 .. 126 158 .. 0.94 4 ! 26.9 0.0 4.8e-09 3.9e-06 2 30 .. 167 195 .. 166 198 .. 0.93 5 ? 3.3 0.0 0.14 1.2e+02 10 23 .. 215 228 .. 214 228 .. 0.92 6 ? 3.5 0.1 0.12 96 19 29 .. 256 266 .. 255 267 .. 0.90 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 3.2e-05 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lG ay + ++ +A++ yek L + FUN_000339-T1 47 DAHLSLGIAYDSHSNFPKAIKGYEKSLNIA 76 799***********************9775 PP == domain 2 score: 19.6 bits; conditional E-value: 9.6e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nl ay + g++ +A+e++ek L + FUN_000339-T1 88 AYLNLLIAYKSIGDFPKAIECFEKSLDIA 116 55555579******************986 PP == domain 3 score: 12.0 bits; conditional E-value: 0.00025 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay g + e +e yek L + FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIA 156 79*************************986 PP == domain 4 score: 26.9 bits; conditional E-value: 4.8e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG a+++ g++ +A+e++e+ L + FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEESLNI 195 79***********************9976 PP == domain 5 score: 3.3 bits; conditional E-value: 0.14 TPR_1 10 ayfklgkydeAley 23 yf+lg++ +A+ey FUN_000339-T1 215 SYFALGDFLKAVEY 228 6***********98 PP == domain 6 score: 3.5 bits; conditional E-value: 0.12 TPR_1 19 eAleyyekALe 29 +A e+y+kAL+ FUN_000339-T1 256 KAREAYNKALR 266 89*******96 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.0 0.00057 0.47 2 32 .. 47 77 .. 46 79 .. 0.92 2 ! 14.3 0.1 5.6e-05 0.046 10 32 .. 95 117 .. 86 119 .. 0.88 3 ! 8.7 0.0 0.0036 3 2 31 .. 127 156 .. 126 158 .. 0.93 4 ! 24.4 0.0 3.3e-08 2.7e-05 2 31 .. 167 196 .. 166 199 .. 0.93 5 ? 2.9 0.0 0.27 2.2e+02 10 23 .. 215 228 .. 214 228 .. 0.91 6 ? 4.8 0.0 0.063 52 19 29 .. 256 266 .. 255 270 .. 0.90 7 ? -2.0 0.2 9.4 7.7e+03 13 27 .. 324 338 .. 323 338 .. 0.86 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00057 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ lG ay ++ +A++ yek+l ++ FUN_000339-T1 47 DAHLSLGIAYDSHSNFPKAIKGYEKSLNIAR 77 68999**********************9875 PP == domain 2 score: 14.3 bits; conditional E-value: 5.6e-05 TPR_2 10 ayyklgdyeeAleayekAleldP 32 ay gd+ +A+e++ek+l ++ FUN_000339-T1 95 AYKSIGDFPKAIECFEKSLDIAR 117 78899**************9976 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0036 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlG ay+ g + e +e yek+l ++ FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIA 156 69*************************986 PP == domain 4 score: 24.4 bits; conditional E-value: 3.3e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlG a+ gd+ +A+e++e++l ++ FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEESLNIA 196 69*************************987 PP == domain 5 score: 2.9 bits; conditional E-value: 0.27 TPR_2 10 ayyklgdyeeAlea 23 +y++lgd+ +A+e+ FUN_000339-T1 215 SYFALGDFLKAVEY 228 79*********997 PP == domain 6 score: 4.8 bits; conditional E-value: 0.063 TPR_2 19 eAleayekAle 29 +A+eay+kAl+ FUN_000339-T1 256 KAREAYNKALR 266 8*********8 PP == domain 7 score: -2.0 bits; conditional E-value: 9.4 TPR_2 13 klgdyeeAleayekA 27 k g+ ++A++ ekA FUN_000339-T1 324 KTGKKDQAANKQEKA 338 789*****9998887 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.0013 1.1 1 36 [] 48 83 .. 48 83 .. 0.95 2 ! 18.0 0.0 3.6e-06 0.0029 1 36 [] 88 123 .. 88 123 .. 0.92 3 ! 7.6 0.0 0.0082 6.8 1 35 [. 128 162 .. 128 163 .. 0.95 4 ! 13.9 0.0 7.4e-05 0.061 1 33 [. 168 200 .. 168 201 .. 0.91 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0013 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +y + ++ +Ai+ ye+ L +a++ +dr+ FUN_000339-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSLNIAREAGDRA 83 7899*****************************985 PP == domain 2 score: 18.0 bits; conditional E-value: 3.6e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L +y + Gd+ +Ai+++e+ L++a++ +dr+ FUN_000339-T1 88 AYLNLLIAYKSIGDFPKAIECFEKSLDIAREAGDRA 123 56788889*************************995 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0082 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y+ G + e i+ ye+ L++a++ +dr FUN_000339-T1 128 AYLNLGTAYEFHGGFSEGIESYEKSLDIARRVGDR 162 789******************************98 PP == domain 4 score: 13.9 bits; conditional E-value: 7.4e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpe 33 a+++L+ ++++ Gd+ +Ai+++e+ L +a + + FUN_000339-T1 168 AYLNLGIAHQSHGDFPKAIECFEESLNIASEAG 200 789*********************999987765 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.0 1.1e-07 8.7e-05 2 44 .. 277 318 .. 276 368 .. 0.83 2 ! 28.0 0.0 3.6e-09 2.9e-06 47 91 .. 480 525 .. 453 544 .. 0.74 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 1.1e-07 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskeltki 44 ++l+G+ + GKtsl k + +f+++e+ t+g+d+ + ++ + FUN_000339-T1 277 IMLIGQDRSGKTSLKKSLQGLQFNPNEDGTVGIDVDPSYFK-V 318 89*********************************887553.2 PP == domain 2 score: 28.0 bits; conditional E-value: 3.6e-09 Roc 47 lendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.srs 91 +++ + +i +WD+aG+ ++++h+l+++++a+++lv+d +r+ FUN_000339-T1 480 VDKMGSEDDIYSVLWDFAGESVYYETHQLFLTSKAIYLLVYDlNRD 525 33333445677889****************************6443 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 1 8.4e+02 3 32 .. 48 77 .. 46 78 .. 0.85 2 ! 19.7 0.1 1.1e-06 0.00088 2 32 .. 87 117 .. 86 118 .. 0.95 3 ! 13.0 0.0 0.00015 0.13 2 32 .. 127 157 .. 126 158 .. 0.95 4 ! 14.4 0.0 5.4e-05 0.044 2 31 .. 167 196 .. 166 198 .. 0.94 5 ? 1.0 0.0 1.1 9e+02 11 23 .. 216 228 .. 215 228 .. 0.89 6 ? 0.8 0.2 1.3 1.1e+03 19 29 .. 256 266 .. 256 267 .. 0.90 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 1 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 a++ lG +y + ++ +A++ yek+l +++ FUN_000339-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSLNIAR 77 67788889999999999*********9986 PP == domain 2 score: 19.7 bits; conditional E-value: 1.1e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nl +y++ gd+ +A+e++ek+l++++ FUN_000339-T1 87 DAYLNLLIAYKSIGDFPKAIECFEKSLDIAR 117 69**************************987 PP == domain 3 score: 13.0 bits; conditional E-value: 0.00015 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y+ g + e +e+yek+l++++ FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIAR 157 69**************************986 PP == domain 4 score: 14.4 bits; conditional E-value: 5.4e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay+nlG ++++ gd+ +A+e++e++l ++ FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEESLNIA 196 69*************************997 PP == domain 5 score: 1.0 bits; conditional E-value: 1.1 TPR_8 11 ylklgdyeeAkey 23 y lgd+ +A+ey FUN_000339-T1 216 YFALGDFLKAVEY 228 8999**9999998 PP == domain 6 score: 0.8 bits; conditional E-value: 1.3 TPR_8 19 eAkeyyekale 29 +A+e+y+kal+ FUN_000339-T1 256 KAREAYNKALR 266 69*******96 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 1.4 1.1e+03 8 34 .. 52 78 .. 50 79 .. 0.85 2 ! 8.0 0.0 0.0051 4.2 6 35 .. 90 119 .. 87 119 .. 0.86 3 ! 8.8 0.0 0.0028 2.3 3 35 .. 127 159 .. 126 159 .. 0.96 4 ! 15.6 0.0 2e-05 0.016 3 32 .. 167 196 .. 166 199 .. 0.92 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 1.4 TPR_10 8 LanalraqgryeeAeelleealairer 34 L+ a+ + ++ A + +e++l i+++ FUN_000339-T1 52 LGIAYDSHSNFPKAIKGYEKSLNIARE 78 899999999999999999999999987 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0051 TPR_10 6 nnLanalraqgryeeAeelleealairerv 35 nL a+ + g++ A e +e++l+i++++ FUN_000339-T1 90 LNLLIAYKSIGDFPKAIECFEKSLDIAREA 119 55557999******************9985 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0028 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL++a+ g + e e +e++l+i++rv FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIARRV 159 5899***************************97 PP == domain 4 score: 15.6 bits; conditional E-value: 2e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealair 32 +++ nL+ a+++ g++ A e +ee+l i+ FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEESLNIA 196 5899***********************986 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.14 1.2e+02 40 74 .. 48 82 .. 25 84 .. 0.85 2 ! 8.6 0.0 0.0032 2.6 40 75 .. 88 123 .. 86 132 .. 0.94 3 ! 14.9 0.0 3.5e-05 0.029 18 82 .. 146 210 .. 129 214 .. 0.81 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.14 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDt 74 a l+l i + + ++ +A+k e + ++Are +D FUN_000339-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSLNIAREAGDR 82 567777777777888899999999*******9997 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0032 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDta 75 a lnl i + ++g+ +A++ +e + +Are +D a FUN_000339-T1 88 AYLNLLIAYKSIGDFPKAIECFEKSLDIAREAGDRA 123 789******************************975 PP == domain 3 score: 14.9 bits; conditional E-value: 3.5e-05 ANAPC5 18 ldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtacLnlals 82 ++s + D++ +++s a lnl i h++ g+ +A++ +ee+ ++A e +D a ++ a + FUN_000339-T1 146 IESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGDFPKAIECFEESLNIASEAGDWAGISRAKQ 210 555556666666666666666799********************************998877765 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 8.6e-10 7.1e-07 44 180 .. 55 191 .. 45 201 .. 0.95 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 8.6e-10 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 ay + ++ +A + ++k ++ ++++++ ++ay++ +yk+ d +A+e++ek+ +i e+g + ++ + +++ ye + +++ ie+Y FUN_000339-T1 55 AYDSHSNFPKAIKGYEKSLNIAREAGDRAREGDAYLNLLIAYKSIgDFPKAIECFEKSLDIAREAGDRAKEGDAYLNLGTAYEFH-GGFSEGIESY 149 5667789999**********************************98999***********************************9.********** PP SNAP 139 eqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e++ d+ + + ++ ++l++ + ++++++kAie +e+ FUN_000339-T1 150 EKSLDIARRVGDRTSEGDAYLNLGIAHQSHGDFPKAIECFEE 191 ****************************************97 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.055 45 28 54 .. 43 70 .. 32 83 .. 0.80 2 ? 4.6 0.0 0.081 67 21 61 .. 74 116 .. 69 121 .. 0.79 3 ? 6.5 0.0 0.02 16 6 59 .. 95 154 .. 90 158 .. 0.79 4 ! 11.2 0.0 0.00067 0.55 2 58 .. 131 193 .. 130 200 .. 0.81 5 ? 0.9 0.0 1.1 9.4e+02 48 61 .. 255 268 .. 253 271 .. 0.69 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.055 TPR_16 28 PeaaaAllglGlallrqgrlaeAa.aay 54 + +A+l lG a+ ++++A+ + FUN_000339-T1 43 AREGDAHLSLGIAYDSHSNFPKAIkGYE 70 67889*******************4444 PP == domain 2 score: 4.6 bits; conditional E-value: 0.081 TPR_16 21 eaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalraa 61 a++++ + +A+l+l a+ g++++A++ +++ l++a FUN_000339-T1 74 NIAREAGdrAREGDAYLNLLIAYKSIGDFPKAIECFEKSLDIA 116 5566666677789999999999999999999999999888665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.02 TPR_16 6 aalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalr 59 a+ gd++ A++++e l+ +A+l+lG a++ g + e ++ y++ l+ FUN_000339-T1 95 AYKSIGDFPKAIECFEKSLDIAreagdrAKEGDAYLNLGTAYEFHGGFSEGIESYEKSLD 154 56667999999999998887777788999999********99987777777777777665 PP == domain 4 score: 11.2 bits; conditional E-value: 0.00067 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +g + + ++ +e l+ + +A+l+lG a+ g++++A++ +++ l FUN_000339-T1 131 NLGTAYEFHGGFSEGIESYEKSLDIArrvgdrTSEGDAYLNLGIAHQSHGDFPKAIECFEESL 193 6788888888888888888887776667789966899******************99888866 PP == domain 5 score: 0.9 bits; conditional E-value: 1.1 TPR_16 48 aeAaaayraalraa 61 ++A++ay++alr++ FUN_000339-T1 255 PKAREAYNKALREG 268 46777777777665 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 1.6 1.3e+03 1 25 [. 47 71 .. 47 75 .. 0.88 2 ? 2.9 0.0 0.35 2.9e+02 8 25 .. 94 111 .. 84 115 .. 0.75 3 ? 4.0 0.0 0.17 1.4e+02 1 25 [. 127 151 .. 127 155 .. 0.88 4 ! 9.4 0.0 0.0031 2.6 1 25 [. 167 191 .. 167 195 .. 0.93 5 ? -0.3 0.0 3.9 3.2e+03 9 22 .. 215 228 .. 214 228 .. 0.88 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.6 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA l l+ +y ++ +A++ +++ FUN_000339-T1 47 DAHLSLGIAYDSHSNFPKAIKGYEK 71 788999*****977*******9997 PP == domain 2 score: 2.9 bits; conditional E-value: 0.35 TPR_6 8 lsylelgdkdeAkaalqr 25 +y+ gd+ +A++ +++ FUN_000339-T1 94 IAYKSIGDFPKAIECFEK 111 466667**********98 PP == domain 3 score: 4.0 bits; conditional E-value: 0.17 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +y+ g + e ++ +++ FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEK 151 8**********98899999888887 PP == domain 4 score: 9.4 bits; conditional E-value: 0.0031 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +++ gd+ +A++ +++ FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEE 191 8***********99********996 PP == domain 5 score: -0.3 bits; conditional E-value: 3.9 TPR_6 9 sylelgdkdeAkaa 22 sy++lgd+ +A+++ FUN_000339-T1 215 SYFALGDFLKAVEY 228 8*******999986 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 9.3 7.6e+03 3 28 .. 48 73 .. 47 82 .. 0.82 2 ! 8.0 0.0 0.0096 7.9 2 30 .. 87 115 .. 86 123 .. 0.88 3 ? 1.4 0.0 1.3 1.1e+03 2 29 .. 127 154 .. 126 159 .. 0.88 4 ? 7.7 0.0 0.012 9.8 2 28 .. 167 193 .. 166 203 .. 0.89 5 ? 0.9 0.0 1.9 1.6e+03 19 31 .. 256 268 .. 253 273 .. 0.83 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 9.3 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+l l+ a+ ++ +A++ +e+ l FUN_000339-T1 48 AHLSLGIAYDSHSNFPKAIKGYEKSL 73 77889999999999999999999876 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0096 TPR_14 2 eawlalarallalGdpdeAlelleralal 30 +a+l l+ a+ Gd+ +A+e++e+ l FUN_000339-T1 87 DAYLNLLIAYKSIGDFPKAIECFEKSLDI 115 68999*******************98875 PP == domain 3 score: 1.4 bits; conditional E-value: 1.3 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+l l+ a++ G ++e +e +e+ l FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLD 154 68999***************99998775 PP == domain 4 score: 7.7 bits; conditional E-value: 0.012 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+l l+ a+ Gd+ +A+e++e+ l FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIECFEESL 193 68999*******************987 PP == domain 5 score: 0.9 bits; conditional E-value: 1.9 TPR_14 19 eAlelleralald 31 +A+e++++al+ FUN_000339-T1 256 KAREAYNKALREG 268 8*********976 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 1 8.5e+02 14 33 .. 47 66 .. 44 67 .. 0.89 2 ? 3.4 0.0 0.2 1.7e+02 14 34 .] 87 107 .. 84 107 .. 0.92 3 ? 4.2 0.0 0.11 93 13 28 .. 126 141 .. 123 147 .. 0.81 4 ? 7.1 0.0 0.013 11 14 34 .] 167 187 .. 164 187 .. 0.93 5 ? -1.0 0.0 5.1 4.2e+03 15 25 .. 215 228 .. 214 237 .. 0.69 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 1 TPR_17 14 dayynLArlllnnGqleeAl 33 da+ L++++ ++ +A+ FUN_000339-T1 47 DAHLSLGIAYDSHSNFPKAI 66 8999********99999997 PP == domain 2 score: 3.4 bits; conditional E-value: 0.2 TPR_17 14 dayynLArlllnnGqleeAlq 34 day nL ++++ G++ +A++ FUN_000339-T1 87 DAYLNLLIAYKSIGDFPKAIE 107 89****************985 PP == domain 3 score: 4.2 bits; conditional E-value: 0.11 TPR_17 13 adayynLArlllnnGq 28 day nL+++++ G FUN_000339-T1 126 GDAYLNLGTAYEFHGG 141 59*********98876 PP == domain 4 score: 7.1 bits; conditional E-value: 0.013 TPR_17 14 dayynLArlllnnGqleeAlq 34 day nL+++++ G++ +A++ FUN_000339-T1 167 DAYLNLGIAHQSHGDFPKAIE 187 8*****************985 PP == domain 5 score: -1.0 bits; conditional E-value: 5.1 TPR_17 15 ayynLArlll...n 25 +y++L+ +l+ FUN_000339-T1 215 SYFALGDFLKaveY 228 79999999875553 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.0 0.00064 0.53 2 47 .. 277 322 .. 276 343 .. 0.86 2 ! 10.1 0.0 0.00074 0.61 45 83 .. 486 524 .. 460 538 .. 0.82 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00064 Ras 2 lvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgke 47 ++l+G+ GK+sl + +F+ + + T+g+d + ++v + FUN_000339-T1 277 IMLIGQDRSGKTSLKKSLQGLQFNPNEDGTVGIDVDPSYFKVTTEV 322 689*******************************988777776655 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00074 Ras 45 gkevklqiwDTAGqerfralreayyrgaegillvydits 83 + ++ +wD AG + + +++++++ + llvyd+++ FUN_000339-T1 486 EDDIYSVLWDFAGESVYYETHQLFLTSKAIYLLVYDLNR 524 45667789****************************986 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.0 0.0032 2.7 18 64 .. 68 114 .. 59 124 .. 0.80 2 ! 10.7 0.0 0.00055 0.45 37 134 .. 127 227 .. 117 228 .. 0.81 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0032 RPN7 18 eLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerare 64 e+ l+ a+e +a+++l y +igd+ +A++++e+ ++ FUN_000339-T1 68 GYEKSLNIAREAGDRAREGDAYLNLLIAYKSIGDFPKAIECFEKSLD 114 55666776677777777778999********************9887 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00055 RPN7 37 raledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekak...sliekggdwerrnrlkvyeGlaalairkf 129 +a+++l+ y+ +g +++ +++ye+ ++ + g + + +++gi+ + + k +e + ++ +++gdw r k y ++++a ++f FUN_000339-T1 127 DAYLNLGTAYEFHGGFSEGIESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGDFPKAIECFEeslNIASEAGDWAGISRAKQYLRISYFALGDF 222 589999999999999999999999999999999999888888888888876666666665555511156678999999999999999999999999 PP RPN7 130 keAak 134 +A + FUN_000339-T1 223 LKAVE 227 99865 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 1.4 1.1e+03 29 38 .. 47 56 .. 47 60 .. 0.93 2 ? 0.1 0.1 1.1 9.1e+02 9 23 .. 61 75 .. 55 78 .. 0.87 3 ? 6.6 0.0 0.011 9.1 3 23 .. 95 115 .. 95 121 .. 0.91 4 ? 2.8 0.1 0.16 1.3e+02 29 39 .. 127 137 .. 122 140 .. 0.90 5 ? 4.2 0.2 0.062 51 29 42 .] 167 180 .. 166 180 .. 0.91 6 ? 3.3 0.0 0.11 95 8 23 .. 180 195 .. 178 199 .. 0.88 7 ? -2.1 0.0 5.6 4.6e+03 4 15 .. 216 227 .. 215 227 .. 0.79 8 ? 2.0 0.1 0.3 2.4e+02 12 22 .. 256 266 .. 255 266 .. 0.88 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.4 TPR_11 29 eayynLGlay 38 +a++ LG ay FUN_000339-T1 47 DAHLSLGIAY 56 79*******9 PP == domain 2 score: 0.1 bits; conditional E-value: 1.1 TPR_11 9 kyeeAieaYkkAlkl 23 ++++Ai+ Y+k l++ FUN_000339-T1 61 NFPKAIKGYEKSLNI 75 6899*******9987 PP == domain 3 score: 6.6 bits; conditional E-value: 0.011 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay + G++++Aie+++k l++ FUN_000339-T1 95 AYKSIGDFPKAIECFEKSLDI 115 68999************9987 PP == domain 4 score: 2.8 bits; conditional E-value: 0.16 TPR_11 29 eayynLGlayy 39 +ay+nLG ay FUN_000339-T1 127 DAYLNLGTAYE 137 89*******96 PP == domain 5 score: 4.2 bits; conditional E-value: 0.062 TPR_11 29 eayynLGlayykqG 42 +ay+nLG a++ G FUN_000339-T1 167 DAYLNLGIAHQSHG 180 79********9877 PP == domain 6 score: 3.3 bits; conditional E-value: 0.11 TPR_11 8 GkyeeAieaYkkAlkl 23 G++++Aie++++ l++ FUN_000339-T1 180 GDFPKAIECFEESLNI 195 99**********9987 PP == domain 7 score: -2.1 bits; conditional E-value: 5.6 TPR_11 4 yyeqGkyeeAie 15 y+++G++ +A+e FUN_000339-T1 216 YFALGDFLKAVE 227 899999888875 PP == domain 8 score: 2.0 bits; conditional E-value: 0.3 TPR_11 12 eAieaYkkAlk 22 +A eaY+kAl+ FUN_000339-T1 256 KAREAYNKALR 266 799******96 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00054 0.45 15 32 .. 60 77 .. 58 81 .. 0.89 2 ? 0.8 0.0 0.62 5.1e+02 17 31 .. 102 116 .. 99 120 .. 0.87 3 ? -0.4 0.0 1.4 1.2e+03 17 31 .. 142 156 .. 141 162 .. 0.82 4 ? 0.4 0.0 0.82 6.7e+02 17 30 .. 182 195 .. 177 198 .. 0.89 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00054 SHNi-TPR 15 enFeqAvkDlrkaLeLre 32 +nF+ A+k ++k+L++ + FUN_000339-T1 60 SNFPKAIKGYEKSLNIAR 77 8**************965 PP == domain 2 score: 0.8 bits; conditional E-value: 0.62 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F+ A++ ++k+L++ FUN_000339-T1 102 FPKAIECFEKSLDIA 116 999*********995 PP == domain 3 score: -0.4 bits; conditional E-value: 1.4 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F++ ++ ++k+L++ FUN_000339-T1 142 FSEGIESYEKSLDIA 156 7788899*****995 PP == domain 4 score: 0.4 bits; conditional E-value: 0.82 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++++L++ FUN_000339-T1 182 FPKAIECFEESLNI 195 999*********98 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.021 17 16 114 .. 21 120 .. 17 125 .. 0.91 2 ! 12.4 0.0 0.00012 0.099 14 113 .. 99 199 .. 94 204 .. 0.91 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.021 TPR_MalT 16 eaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 + e +++ ++ L++ e +ar + a+l+lG a+ ++ +A + +++ +ar+a++ + a+l + + G++ +A+e +++ l a FUN_000339-T1 21 SVREPMDHHEKHLNIAGEAHNPAReGDAHLSLGIAYDSHSNFPKAIKGYEKSLNIAREAGDRAREGDAYLNLLIAYKSIGDFPKAIECFEKSLDIA 116 56677888889999999999999999************************************99999999999999999****************9 PP TPR_MalT 111 qesk 114 +e++ FUN_000339-T1 117 REAG 120 9986 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00012 TPR_MalT 14 qgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++++a+e ++ L++ +e a+ + a+l+lG+a+ g ++++ +++++ +arr ++ ++ a+l ++ ++ G++ +A+e +++ l FUN_000339-T1 99 IGDFPKAIECFEKSLDIAREAGDRAKeGDAYLNLGTAYEFHGGFSEGIESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGDFPKAIECFEESLN 194 58899999999999999998766665699******************************************************************9 PP TPR_MalT 109 laqes 113 a e+ FUN_000339-T1 195 IASEA 199 99886 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.028 23 37 66 .. 94 123 .. 87 124 .. 0.90 2 ! 7.9 0.0 0.0054 4.5 32 65 .. 169 202 .. 165 210 .. 0.86 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.028 TPR_9 37 llyaqlgcleaAladLeaylalapdapdae 66 ++y g++ +A++++e+ l++a +a d++ FUN_000339-T1 94 IAYKSIGDFPKAIECFEKSLDIAREAGDRA 123 567789*****************9999985 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0054 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalapdapda 65 + + G++++ g++ +A++++e l +a +a d FUN_000339-T1 169 YLNLGIAHQSHGDFPKAIECFEESLNIASEAGDW 202 6789******************999999888775 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.48 3.9e+02 149 175 .. 60 86 .. 46 88 .. 0.82 2 ? 7.8 0.0 0.0046 3.8 135 175 .. 87 126 .. 78 128 .. 0.93 3 ? 2.0 0.0 0.27 2.2e+02 135 175 .. 127 166 .. 126 168 .. 0.84 4 ? 0.6 0.0 0.75 6.2e+02 135 170 .. 167 201 .. 166 207 .. 0.90 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.48 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkeep 175 ++ +a+k +e++l +a+++g+r++e FUN_000339-T1 60 SNFPKAIKGYEKSLNIAREAGDRAREG 86 5688999***************99875 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0046 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ ++ + +a++++e++l +a+++g+r++e FUN_000339-T1 87 DAYLNLLIAYKSI-GDFPKAIECFEKSLDIAREAGDRAKEG 126 7999999999998.999********************9986 PP == domain 3 score: 2.0 bits; conditional E-value: 0.27 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ + e +++ ++ +e++l +a+++g+r +e FUN_000339-T1 127 DAYLNLGTAYEFH-GGFSEGIESYEKSLDIARRVGDRTSEG 166 6788887777777.789999****************98875 PP == domain 4 score: 0.6 bits; conditional E-value: 0.75 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgk 170 daYl+ +++ + +a++++e +l +a ++g+ FUN_000339-T1 167 DAYLNLGIAHQSH-GDFPKAIECFEESLNIASEAGD 201 79***99999999.9999*************99876 PP >> G-alpha G-protein alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.2 5.5e-05 0.045 4 128 .. 258 410 .. 255 429 .. 0.61 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 5.5e-05 G-alpha 4 skeidkqlkeekkkakkevklLllGageSGKsTilkqmkilhkkgfseeerkeyraviysnilrslktllealekleiel..............ee 85 ++ +k l+e k++ k+ + ++l+G+ SGK+++ k ++ l + ++ + + y ++ + +++ ++ + +++ e+ FUN_000339-T1 258 REAYNKALREGKTRVKR-IPIMLIGQDRSGKTSLKKSLQGLQFNPNEDGTVGIDVDPSYFKVTTEVWKTGKKDQAANKQEkapsfehhvarvvvEN 352 56678888888888888.*********************777444333333223333444444444444444444444445666677777777755 PP G-alpha 86 eenkerlkkllslesslk...............eeeefsselaeaikelwndpgiqev 128 +++e ++++++++s+ e++e+ +++ +++ +d++i ++ FUN_000339-T1 353 LKEQELPSEVKAVDESKDlessppmsteapiasETNEIAEDYRGPSSKIIHDQVIASA 410 5555555555555554444445556666666655555555666666777777766655 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 8.1e-05 0.067 4 26 .. 277 299 .. 273 310 .. 0.90 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.1e-05 PduV-EutP 4 illiGkvgsGKttLtqalkgeel 26 i+liG+ sGKt+L+++l+g+++ FUN_000339-T1 277 IMLIGQDRSGKTSLKKSLQGLQF 299 9******************9876 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.014 11 10 32 .. 52 74 .. 48 85 .. 0.88 2 ? 0.0 0.0 1.6 1.3e+03 18 33 .. 100 115 .. 94 126 .. 0.83 3 ? -1.4 0.0 4.4 3.6e+03 11 32 .. 133 154 .. 113 156 .. 0.67 4 ? 1.8 0.0 0.44 3.6e+02 11 32 .. 173 194 .. 164 204 .. 0.84 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.014 MIT 10 kAveeDnagnyeeAlelYkeale 32 + +D+ n+ +A++ Y+++l+ FUN_000339-T1 52 LGIAYDSHSNFPKAIKGYEKSLN 74 57899***************997 PP == domain 2 score: 0.0 bits; conditional E-value: 1.6 MIT 18 gnyeeAlelYkealel 33 g++ +A+e+++++l+ FUN_000339-T1 100 GDFPKAIECFEKSLDI 115 7889999999999985 PP == domain 3 score: -1.4 bits; conditional E-value: 4.4 MIT 11 AveeDnagnyeeAlelYkeale 32 + ++ g ++e +e Y+++l+ FUN_000339-T1 133 GTAYEFHGGFSEGIESYEKSLD 154 4455555666777777777776 PP == domain 4 score: 1.8 bits; conditional E-value: 0.44 MIT 11 AveeDnagnyeeAlelYkeale 32 + + g++ +A+e+++e+l+ FUN_000339-T1 173 GIAHQSHGDFPKAIECFEESLN 194 56667889***********997 PP >> Cdc6_lid Cdc6 AAA+ ATPase-type lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 7.6 6.3e+03 40 53 .. 73 86 .. 71 91 .. 0.75 2 ? 4.1 0.0 0.076 62 29 56 .. 95 122 .. 88 128 .. 0.85 3 ? 5.3 0.0 0.03 25 28 55 .. 174 201 .. 169 203 .. 0.92 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 7.6 Cdc6_lid 40 ldlLrkAgelAere 53 l++ r+Ag+ A++ FUN_000339-T1 73 LNIAREAGDRAREG 86 77778899988875 PP == domain 2 score: 4.1 bits; conditional E-value: 0.076 Cdc6_lid 29 aaqesGDaRrAldlLrkAgelAeregse 56 a ++ GD +A++ ++k+ ++A++ g++ FUN_000339-T1 95 AYKSIGDFPKAIECFEKSLDIAREAGDR 122 6677899999999999999999999876 PP == domain 3 score: 5.3 bits; conditional E-value: 0.03 Cdc6_lid 28 laaqesGDaRrAldlLrkAgelAeregs 55 +a q++GD +A++ ++++ ++A + g+ FUN_000339-T1 174 IAHQSHGDFPKAIECFEESLNIASEAGD 201 7899*******************99875 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.0027 2.2 2 17 .. 277 292 .. 276 341 .. 0.82 2 ? 2.7 0.0 0.12 99 21 68 .. 462 510 .. 457 524 .. 0.82 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0027 Gtr1_RagA 2 vLLmGksksGKsSirs 17 ++L+G+ +sGK+S+++ FUN_000339-T1 277 IMLIGQDRSGKTSLKK 292 89************98 PP == domain 2 score: 2.7 bits; conditional E-value: 0.12 Gtr1_RagA 21 snyspkdtlrlgatidveksevrflgnltlnlwdlgGqekflde.ylts 68 s ++p+++ +l + e +++ + + ++ lwd+ G + + ++ +l FUN_000339-T1 462 SAMIPEEIETLIKKLRDEVDKMGSEDDIYSVLWDFAGESVYYEThQLFL 510 6799999999999999999*******************99998733444 PP >> NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.02 17 22 68 .. 20 66 .. 8 84 .. 0.84 2 ? 3.4 0.0 0.16 1.3e+02 21 58 .. 99 136 .. 70 142 .. 0.82 3 ? -1.5 0.0 5.5 4.6e+03 21 41 .. 179 199 .. 169 211 .. 0.80 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.02 NRBF2_MIT 22 Gkyeeaischkkaaaylseamkltkseqahlslelqreshikqllli 68 G e + h+k ++ ea + ++ ahlsl + +sh + i FUN_000339-T1 20 GSVREPMDHHEKHLNIAGEAHNPAREGDAHLSLGIAYDSHSNFPKAI 66 566788889999999*************************8765555 PP == domain 2 score: 3.4 bits; conditional E-value: 0.16 NRBF2_MIT 21 aGkyeeaischkkaaaylseamkltkseqahlslelqr 58 G + +ai c +k+ ++ ea +k a l l FUN_000339-T1 99 IGDFPKAIECFEKSLDIAREAGDRAKEGDAYLNLGTAY 136 5899*****************99999999999886655 PP == domain 3 score: -1.5 bits; conditional E-value: 5.5 NRBF2_MIT 21 aGkyeeaischkkaaaylsea 41 G + +ai c + + ++ sea FUN_000339-T1 179 HGDFPKAIECFEESLNIASEA 199 477888899988887777776 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.0041 3.4 95 142 .. 104 152 .. 71 203 .. 0.64 2 ? 1.4 0.0 0.16 1.3e+02 115 159 .. 311 355 .. 304 373 .. 0.85 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0041 TPR_IF140-IFT172 95 qasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 +a + ++k+l++a++ dr + ++y n e +g ++e i+ yeks FUN_000339-T1 104 KAIECFEKSLDIAREAgDRAKEGDAYLNLGTAYEFHGGFSEGIESYEKS 152 4444555555555432255555555555555555555555555555554 PP == domain 2 score: 1.4 bits; conditional E-value: 0.16 TPR_IF140-IFT172 115 lrktyynyakhleakgdieeaiklyeksethrfevPrlLfddtea 159 + y++ + ++ ++g+ ++a+++ ek+ +++v r+++++ ++ FUN_000339-T1 311 VDPSYFKVTTEVWKTGKKDQAANKQEKAPSFEHHVARVVVENLKE 355 5668999999999**************************998654 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.018 15 64 113 .. 57 106 .. 54 119 .. 0.91 2 ? 0.9 0.0 0.71 5.9e+02 73 114 .. 106 147 .. 101 163 .. 0.85 3 ? 0.9 0.0 0.76 6.2e+02 69 113 .. 142 186 .. 136 199 .. 0.84 4 ? 2.0 0.0 0.33 2.7e+02 65 116 .. 178 229 .. 177 237 .. 0.89 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.018 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Dsh ++ + + ye ln+a+ g ++ e +a +L ay++ G++ +ai FUN_000339-T1 57 DSHSNFPKAIKGYEKSLNIAREAGDRAREGDAYLNLLIAYKSIGDFPKAI 106 9*******************************999999999999988776 PP == domain 2 score: 0.9 bits; conditional E-value: 0.71 Ulvan_lyase_2nd 73 eelyelalnlakrkgyteleekaealLkqaydaeGgykpaik 114 e +e l++a+ g ++ e +a +L ay+ +Gg+++ i+ FUN_000339-T1 106 IECFEKSLDIAREAGDRAKEGDAYLNLGTAYEFHGGFSEGIE 147 57899999***********************99999998775 PP == domain 3 score: 0.9 bits; conditional E-value: 0.76 Ulvan_lyase_2nd 69 ndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 + e e+ye l++a+r g ++ e +a +L a +++G++ +ai FUN_000339-T1 142 FSEGIESYEKSLDIARRVGDRTSEGDAYLNLGIAHQSHGDFPKAI 186 5566789***************99999999999999999987776 PP == domain 4 score: 2.0 bits; conditional E-value: 0.33 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpaikts 116 sh ++ + e +e ln+a+ g + +a+++L+ +y a G++ +a++++ FUN_000339-T1 178 SHGDFPKAIECFEESLNIASEAGDWAGISRAKQYLRISYFALGDFLKAVEYR 229 67778888999********************************999888765 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.023 19 3 25 .. 89 111 .. 87 114 .. 0.91 2 ? 3.2 0.0 0.21 1.7e+02 12 25 .. 178 191 .. 169 194 .. 0.89 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.023 PPR 3 ynslIsgycknGkleeAlelfke 25 y l+ +y + G++ +A+e+f++ FUN_000339-T1 89 YLNLLIAYKSIGDFPKAIECFEK 111 88899****************97 PP == domain 2 score: 3.2 bits; conditional E-value: 0.21 PPR 12 knGkleeAlelfke 25 ++G++ +A+e+f+e FUN_000339-T1 178 SHGDFPKAIECFEE 191 69**********98 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.00037 0.31 4 70 .. 264 330 .. 261 337 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00037 Arf 4 ilaklklkkkelrilllGLDnaGKtTilkklkleelv.ttiPTigfnveeveiknlkftvwDvGGqek 70 l++ k++ k + i+l+G D +GKt + k l+ +++ + T+g +v+ ++ +++ +vw G +++ FUN_000339-T1 264 ALREGKTRVKRIPIMLIGQDRSGKTSLKKSLQGLQFNpNEDGTVGIDVDP-SYFKVTTEVWKTGKKDQ 330 5666677789999******************9988872578899999986.67789999999887776 PP >> ssDBP Phage single-stranded DNA-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 2.8 2.3e+03 27 47 .. 53 73 .. 45 83 .. 0.80 2 ? -0.8 0.0 2.5 2e+03 28 50 .. 94 116 .. 77 123 .. 0.72 3 ? 7.6 0.0 0.006 4.9 17 57 .. 164 203 .. 155 210 .. 0.86 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 2.8 ssDBP 27 afahledapfPqkisyyvesk 47 + a+ + +fP+ i+ y +s FUN_000339-T1 53 GIAYDSHSNFPKAIKGYEKSL 73 67899999******9998885 PP == domain 2 score: -0.8 bits; conditional E-value: 2.5 ssDBP 28 fahledapfPqkisyyveskdev 50 a+++ +fP+ i+ + +s d FUN_000339-T1 94 IAYKSIGDFPKAIECFEKSLDIA 116 57788889******999996655 PP == domain 3 score: 7.6 bits; conditional E-value: 0.006 ssDBP 17 akGnpYtmaeafahledapfPqkisyyveskdevlpaGeye 57 ++G++Y ++ + ah++ +fP+ i+ + es + +aG+++ FUN_000339-T1 164 SEGDAY-LNLGIAHQSHGDFPKAIECFEESLNIASEAGDWA 203 468888.57799******************99999999997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (551 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 737 (0.028851); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 31 (0.00121354); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 31 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 5398.39 // Query: FUN_000340-T1 [L=677] Description: FUN_000340 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-18 67.2 0.5 4e-18 66.2 0.5 1.6 1 COR-A C-terminal of Roc, COR-A domain 0.00095 19.7 0.0 0.0038 17.8 0.0 2.0 2 Death Death domain Domain annotation for each model (and alignments): >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.2 0.5 3.1e-22 4e-18 1 142 [] 111 271 .. 111 271 .. 0.91 Alignments for each domain: == domain 1 score: 66.2 bits; conditional E-value: 3.1e-22 COR-A 1 Pkswlevreelee.kkseknyisleeyreicke.nglkeeeeqdrllkfLhdlGvllyfqddeelkdlviLkpeWlteavykvlds.......... 84 P +wl+++++l+ ++ +++i++e+ +i++e +++ +++e ++l+fLhd l++f+d el++lv+L+p+Wl+++ +v++ FUN_000340-T1 111 PIKWLRYEKALQVtLAEGHKCITIEHAEQIASEvCQIGDRQEFVTMLDFLHDQRILIHFDDTVELNKLVVLDPQWLIDVFKAVITVkpfhlqekgf 206 89**********988999************98658**************************99**********************99999999999 PP COR-A 85 ...kevlkkkGllkeedlkkiwkek.ypaeehdellrlmekfelcyelek...eeedtylvpqlL 142 ++l+++G+l+e+ l++ w + ++++ + l+ +mekf l + ++ +++ylvp++L FUN_000340-T1 207 kdmWRTLEREGILEEKPLQHAWGQIaEERHTFERLIAIMEKFSLLCSWSSsdePCSKKYLVPSML 271 7776677899*************97788888899**********99988865545689****987 PP >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 0.72 9.2e+03 53 73 .. 228 248 .. 224 251 .. 0.80 2 ! 17.8 0.0 3e-07 0.0038 15 81 .. 615 676 .. 605 677 .] 0.91 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 0.72 Death 53 WearegknatvgnLleaLrkl 73 W + + +t+++L+++++k FUN_000340-T1 228 WGQIAEERHTFERLIAIMEKF 248 777777889999999999885 PP == domain 2 score: 17.8 bits; conditional E-value: 3e-07 Death 15 gkdWreLarklglseeeideiesenrdlrsqtyelLklWearegknatvgnLleaLrklgrrdaaek 81 g+ W+ +a++lgl+ ei+++ + r ++++ L +r + +v++L+++L+++g+ +a++ FUN_000340-T1 615 GEGWKVVAERLGLNAKEIRYLDVRV---RNPCEAALSVVSQR--RCMNVDDLYDVLTECGMPVLADI 676 799**********************...**************..7777************9987776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (677 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 947 (0.0370718); expected 510.9 (0.02) Passed bias filter: 701 (0.0274418); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6549.37 // Query: FUN_000341-T1 [L=1860] Description: FUN_000341 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-114 374.3 6.8 1e-15 58.1 0.0 9.0 8 TPR_12 Tetratricopeptide repeat 1.1e-106 345.2 50.0 1.2e-07 31.7 0.1 15.6 15 TPR_1 Tetratricopeptide repeat 8.6e-84 282.2 0.0 1.5e-83 281.4 0.0 1.4 1 GT4-conflict Family 4 Glycosyltransferase in co 5.6e-80 257.2 11.6 6.5e-05 23.2 0.0 14.2 13 TPR_7 Tetratricopeptide repeat 6.5e-76 244.7 53.4 5.9e-06 26.5 0.3 15.0 14 TPR_2 Tetratricopeptide repeat 5.2e-72 232.4 56.4 8.2e-06 26.1 0.2 15.0 14 TPR_8 Tetratricopeptide repeat 3.5e-48 160.8 15.9 0.032 14.7 0.0 13.7 13 TPR_10 Tetratricopeptide repeat 1.1e-34 120.7 24.4 6.8e-11 42.6 3.4 4.6 4 SNAP Soluble NSF attachment protein, SN 1.7e-28 97.7 13.2 1.1 10.6 0.0 14.2 13 TPR_6 Tetratricopeptide repeat 2.9e-28 98.4 10.9 0.018 15.9 0.0 12.0 13 TPR_16 Tetratricopeptide repeat 5.9e-27 94.7 6.5 4.4 8.0 0.0 13.8 13 DUF7018 Domain of unknown function (DUF701 2.7e-24 83.8 0.0 17 6.5 0.0 14.1 13 TPR_17 Tetratricopeptide repeat 3.2e-23 81.6 62.2 0.062 13.5 0.7 20.5 16 TPR_11 TPR repeat 3e-20 73.3 0.0 7.1e-06 26.0 0.0 5.4 7 TPR_MalT MalT-like TPR region 1.3e-19 71.3 0.0 2.7e-19 70.3 0.0 1.6 1 Glyco_trans_1_4 Glycosyl transferases group 1 2.3e-19 70.1 0.0 4.9e-19 69.0 0.0 1.5 1 Glycos_transf_1 Glycosyl transferases group 1 2e-17 63.9 3.4 3.9e-17 63.0 2.3 2.2 1 COR-A C-terminal of Roc, COR-A domain 2.7e-17 63.0 2.2 0.67 10.5 0.0 9.2 8 TPR_9 Tetratricopeptide repeat 1.4e-16 59.8 12.5 21 6.7 0.0 13.4 13 TPR_14 Tetratricopeptide repeat 1.1e-14 54.7 35.1 0.92 10.7 0.3 13.6 13 Sel1 Sel1 repeat 2.4e-14 54.1 20.1 6.2 7.1 0.1 12.7 13 DUF7380 Domain of unknown function (DUF738 3.5e-14 53.6 0.2 4.1e-06 27.5 0.1 3.1 2 Roc Ras of Complex, Roc, domain of DAP 4.4e-13 49.9 2.1 2.7 8.9 0.0 7.7 8 ANAPC3 Anaphase-promoting complex, cyclos 5.4e-12 46.3 4.9 1.5 8.9 0.0 10.0 11 ComR_TPR ComR tetratricopeptide 7.1e-11 41.9 24.0 0.044 12.9 2.6 7.7 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 3.3e-08 34.2 0.1 8.8 7.3 0.0 7.6 8 Bleomycin_resist_prot_dom Bleomycin resistance protein domai 3.5e-08 33.8 1.4 50 4.5 0.0 8.6 6 VGCC_beta4Aa_N Voltage gated calcium channel subu 4.2e-08 34.1 15.3 22 5.7 0.0 11.9 12 ARM_TT21_4th Tetratricopeptide repeat protein 2 1.6e-07 31.8 25.7 6.8 7.4 0.0 13.2 14 MIT MIT (microtubule interacting and t 7.9e-07 29.5 7.8 0.88 10.2 0.0 8.6 11 ANAPC5 Anaphase-promoting complex subunit 1.4e-06 28.8 22.9 0.13 12.6 0.9 8.0 6 ARM_TT21_C Tetratricopeptide repeat protein 2 3.4e-06 27.2 13.4 2.1 8.2 0.0 6.9 7 SPO22 Meiosis protein SPO22/ZIP4 like 5.2e-06 27.0 4.6 5.9 7.6 0.0 6.0 5 TPR_P4H Prolyl 4-hydroxylase peptide-subst 2.9e-05 24.7 0.0 63 4.2 0.0 7.0 9 Cerato-platanin Cerato-platanin 4.1e-05 24.2 7.9 56 4.2 0.1 8.2 10 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain 9.2e-05 22.8 31.5 3.6 8.1 0.1 11.6 13 ssDBP Phage single-stranded DNA-binding 0.00027 21.0 0.0 0.66 10.0 0.0 2.5 2 Ras Ras family 0.00065 20.2 0.0 0.0036 17.8 0.0 2.1 2 Glyco_transf_4 Glycosyltransferase Family 4 ------ inclusion threshold ------ 0.074 13.3 0.0 0.16 12.3 0.0 1.5 1 PduV-EutP Ethanolamine utilisation - propane 0.12 12.8 21.0 1.3e+02 3.2 0.1 9.4 9 YARHG YARHG domain 7.6 6.6 8.4 97 3.0 0.1 5.7 8 Phage_tail_tube_init Putative phage tail tube initiator Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.5 0.0 5.3e-18 3.3e-15 4 77 .] 4 75 .. 2 75 .. 0.96 2 ! 53.4 0.0 4.8e-17 3e-14 6 77 .] 86 155 .. 81 155 .. 0.95 3 ! 57.2 0.0 3.2e-18 2e-15 6 77 .] 166 235 .. 162 235 .. 0.96 4 ! 52.7 0.1 8.4e-17 5.2e-14 12 77 .] 252 315 .. 244 315 .. 0.94 5 ! 56.6 0.0 5e-18 3.1e-15 4 77 .] 324 395 .. 321 395 .. 0.96 6 ! 58.1 0.0 1.7e-18 1e-15 4 77 .] 404 475 .. 401 475 .. 0.96 7 ! 32.5 0.0 1.7e-10 1e-07 4 62 .. 484 540 .. 481 541 .. 0.94 8 ? 1.1 0.0 1.1 6.6e+02 28 60 .. 543 573 .. 542 576 .. 0.89 Alignments for each domain: == domain 1 score: 56.5 bits; conditional E-value: 5.3e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a++n+++++ + ++ +A+e++ek+l++a+++ +d++ + +++nLg +y + d+ +A+e++e++l+ia++ FUN_000341-T1 4 RAYLNIGSAYKSQSDFLKAIECYEKSLNIAREA--GDRDCEKDVYFNLGVAYNSQSDFPKAIECYEKSLNIARE 75 6899*****************************..89999*******************************986 PP == domain 2 score: 53.4 bits; conditional E-value: 4.8e-17 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ l+ ++ + ++ +A+e++ek+l++a+++ +d++ + +a++nLg +y + d+ +A+e++e++l+ia++ FUN_000341-T1 86 YLSLGVAYDSQSDFPKAIECYEKSLNIAREA--GDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIARE 155 6679999999*********************..88999*******************************986 PP == domain 3 score: 57.2 bits; conditional E-value: 3.2e-18 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + nl++++ + ++ +A+e++ek+l++a+++ +d++ + +a++n+g +y+ + d+ +A+e++e++l+ia++ FUN_000341-T1 166 YFNLGMAYNSQSDFPKAIECYEKSLNIAREA--GDRDTEGRAYFNIGFAYESQRDFPKAIECYEKSLNIARE 235 669****************************..88999*******************************986 PP == domain 4 score: 52.7 bits; conditional E-value: 8.4e-17 TPR_12 12 vlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ + ++ +A+e++ek+l++a+++ +d++ + +a++nLg +y + d+ +A+e++e++l+ia++ FUN_000341-T1 252 AYNSQRDFPKAIECYEKSLNIAREA--GDRDTEGRAYFNLGKAYKSQRDFSKAIEWYEKSLNIARE 315 68899********************..88999*******************************986 PP == domain 5 score: 56.6 bits; conditional E-value: 5e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ n+++++ + ++ +A+e++ek+l++a+++ +d+++ a++nLg +y + d+ +A+e++e++l+ia++ FUN_000341-T1 324 RAYFNIGFAYESQRDFPKAIECYEKSLDIAREA--GDRDGGKKAYFNLGVAYNSQSDFPKAIECYEKSLNIARE 395 6889*****************************..88999*******************************986 PP == domain 6 score: 58.1 bits; conditional E-value: 1.7e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+ ++ + ++ +A+e++ek+l++a+++ +d++ + +a++nLg +y + d+ +A+e++e++l+ia++ FUN_000341-T1 404 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREA--GDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIARE 475 6889*****************************..88999*******************************986 PP == domain 7 score: 32.5 bits; conditional E-value: 1.7e-10 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdye 62 +a+ nl+ ++ + ++ +A+e++ek+l++a+++ +d++++ +++ Lg +y + d+ FUN_000341-T1 484 RAYFNLGKAYKSQRDFPKAIECYEKSLNIAREA--GDRDGEKDVYFSLGNAYNSQSDFP 540 6889*****************************..89999*************999986 PP == domain 8 score: 1.1 bits; conditional E-value: 1.1 TPR_12 28 kalelaerllGpdhpltatalrnLgrlylalgd 60 k+l++a+++ +d ++++a + ++ yl lg+ FUN_000341-T1 543 KSLNIAREA--GDQGGVIRASYYVAESYLGLGN 573 89****999..7777*************99998 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.2 2.4e-08 1.5e-05 2 31 .. 4 33 .. 3 35 .. 0.93 2 ! 30.2 0.0 5.9e-10 3.7e-07 2 31 .. 44 73 .. 44 75 .. 0.92 3 ! 25.1 0.0 2.3e-08 1.5e-05 2 31 .. 84 113 .. 84 115 .. 0.92 4 ! 27.5 0.2 4.2e-09 2.6e-06 2 31 .. 124 153 .. 123 155 .. 0.93 5 ! 30.2 0.0 6e-10 3.7e-07 2 31 .. 164 193 .. 164 195 .. 0.92 6 ! 29.6 0.1 8.9e-10 5.5e-07 2 31 .. 204 233 .. 203 235 .. 0.93 7 ! 17.9 0.3 4.5e-06 0.0028 3 31 .. 245 273 .. 244 275 .. 0.87 8 ! 27.7 0.3 3.6e-09 2.2e-06 2 31 .. 284 313 .. 283 315 .. 0.93 9 ! 31.2 0.1 2.8e-10 1.8e-07 2 31 .. 324 353 .. 323 355 .. 0.94 10 ! 31.7 0.1 1.9e-10 1.2e-07 2 31 .. 364 393 .. 364 395 .. 0.93 11 ! 27.5 0.2 4.2e-09 2.6e-06 2 31 .. 404 433 .. 403 435 .. 0.93 12 ! 27.5 0.2 4.2e-09 2.6e-06 2 31 .. 444 473 .. 443 475 .. 0.93 13 ! 31.2 0.2 2.9e-10 1.8e-07 2 31 .. 484 513 .. 483 515 .. 0.93 14 ? 5.3 0.0 0.042 26 2 18 .. 524 540 .. 524 541 .. 0.89 15 ? 2.8 0.0 0.27 1.7e+02 19 28 .. 588 597 .. 587 598 .. 0.89 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 2.4e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ n+G ay ++ ++ +A+e+yek L + FUN_000341-T1 4 RAYLNIGSAYKSQSDFLKAIECYEKSLNIA 33 79************************9775 PP == domain 2 score: 30.2 bits; conditional E-value: 5.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlG+ay ++ ++ +A+e+yek L + FUN_000341-T1 44 DVYFNLGVAYNSQSDFPKAIECYEKSLNIA 73 58************************9775 PP == domain 3 score: 25.1 bits; conditional E-value: 2.3e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +++ lG+ay ++ ++ +A+e+yek L + FUN_000341-T1 84 DVYLSLGVAYDSQSDFPKAIECYEKSLNIA 113 5799**********************9775 PP == domain 4 score: 27.5 bits; conditional E-value: 4.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay ++ ++ +A+e yek L + FUN_000341-T1 124 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIA 153 79************************9775 PP == domain 5 score: 30.2 bits; conditional E-value: 6e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ++++nlG+ay ++ ++ +A+e+yek L + FUN_000341-T1 164 DVYFNLGMAYNSQSDFPKAIECYEKSLNIA 193 58************************9775 PP == domain 6 score: 29.6 bits; conditional E-value: 8.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++n+G ay ++ ++ +A+e+yek L + FUN_000341-T1 204 RAYFNIGFAYESQRDFPKAIECYEKSLNIA 233 79************************9775 PP == domain 7 score: 17.9 bits; conditional E-value: 4.5e-06 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a++nl +ay ++ ++ +A+e+yek L + FUN_000341-T1 245 AYFNLEVAYNSQRDFPKAIECYEKSLNIA 273 7777779******************9775 PP == domain 8 score: 27.7 bits; conditional E-value: 3.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay ++ ++ +A+e yek L + FUN_000341-T1 284 RAYFNLGKAYKSQRDFSKAIEWYEKSLNIA 313 79************************9775 PP == domain 9 score: 31.2 bits; conditional E-value: 2.8e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++n+G ay ++ ++ +A+e+yek L + FUN_000341-T1 324 RAYFNIGFAYESQRDFPKAIECYEKSLDIA 353 79*************************986 PP == domain 10 score: 31.7 bits; conditional E-value: 1.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka++nlG+ay ++ ++ +A+e+yek L + FUN_000341-T1 364 KAYFNLGVAYNSQSDFPKAIECYEKSLNIA 393 79************************9775 PP == domain 11 score: 27.5 bits; conditional E-value: 4.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay ++ ++ +A+e yek L + FUN_000341-T1 404 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIA 433 79************************9775 PP == domain 12 score: 27.5 bits; conditional E-value: 4.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay ++ ++ +A+e yek L + FUN_000341-T1 444 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIA 473 79************************9775 PP == domain 13 score: 31.2 bits; conditional E-value: 2.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay ++ ++ +A+e+yek L + FUN_000341-T1 484 RAYFNLGKAYKSQRDFPKAIECYEKSLNIA 513 79************************9775 PP == domain 14 score: 5.3 bits; conditional E-value: 0.042 TPR_1 2 kalynlGnayfklgkyd 18 ++++ lGnay ++ ++ FUN_000341-T1 524 DVYFSLGNAYNSQSDFP 540 589***********996 PP == domain 15 score: 2.8 bits; conditional E-value: 0.27 TPR_1 19 eAleyyekAL 28 Ale+y+kAL FUN_000341-T1 588 RALEAYNKAL 597 59*******9 PP >> GT4-conflict Family 4 Glycosyltransferase in conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 281.4 0.0 2.5e-86 1.5e-83 3 385 .] 1477 1842 .. 1475 1842 .. 0.91 Alignments for each domain: == domain 1 score: 281.4 bits; conditional E-value: 2.5e-86 GT4-conflict 3 vatewssakGGistfNreLceaLAaaga.eviclVpeaseeeiadAkaagVrLvkaeaepgvsereslllrrpelpagvepdlviGHgrvtGpa 95 + ew+s kGG+st+Nre+ + LA+ + ev + p+ see+ ++A++++VrL+ka+++pg l++ +p++ + d+viGHg + G+ FUN_000341-T1 1477 LTSEWGSTKGGLSTMNREISIQLAKDDNvEVCMYLPAFSEEDKKAADKCRVRLLKAKKKPGYDPID-WLAS---IPSDHQMDVVIGHGIHLGKQ 1566 567***********************998********************************99988.4444...4456677************* PP GT4-conflict 96 AkalaedfypdakrvhfvHmapdelewlkekrdaaeraeerekierelaakAdlvvaVGprLaeearrllseapgepkvleldpgfdveaeeep 189 +++e + p++k v++vH++p+e ++k+ d+++++e++ + e+el+++Ad vva+Gp+La+++ + + +v l+pg+ e+++ + FUN_000341-T1 1567 IPHIKESH-PECKWVQVVHTDPEECGMFKTYADPTAKGEKKYEAEVELCKQADQVVAIGPKLADTYSHSCG----KGEVFDLTPGIFSEFANMK 1655 ********.**********************************************************9983....349*********9999988 PP GT4-conflict 190 rtppeggklkvLllGRae..DaelKgldlAaravgrlakesrderveLvvrGapaeeaeelrerlaeiagepalevtvrpytkdraeleadlrr 281 + + e+++++vL++GR + D +lKg+d+Aa av++l + ++++ +Lv +Gapa++ eel+er+ + + ++ ++tvr+ k r+el++++ + FUN_000341-T1 1656 QDIGEKRTFQVLVFGRGDseDFQLKGYDIAACAVAKLKD--EEHPFKLVFVGAPAGKEEELKERFL-LQDISRRQLTVRR-AKKREELAQQFYE 1745 9999************9999*****************88..6677**************9998876.4555566799999.67899******** PP GT4-conflict 282 aslvlmPSraEGFGLvglEAiaagvPvLvsseSGlaelLeek.lseeeaerlvvpvtgddeedaeewaraieevlrdlea.aferaaelreeLa 373 a+lv+mPSr+EGFGL++lEA++ag+PvLvss+SGl+ Le+ + ++++vv+ ++ + ewa+ai++v +++++ + ++a +lr++ + FUN_000341-T1 1746 ADLVIMPSRTEGFGLAALEALSAGLPVLVSSNSGLGVALEKVpF----GTNFVVNSED-P----TEWAKAIRRVRSKHRNvRLREASDLRKNYS 1830 ***************************************99933....5679999444.4....69********97655516789********9 PP GT4-conflict 374 erltWaaaaasL 385 e + W++ +++L FUN_000341-T1 1831 ETYNWEKQCSQL 1842 99*****99886 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 2.8e-05 0.018 1 35 [. 5 39 .. 5 40 .. 0.96 2 ! 16.4 0.0 1.6e-05 0.01 2 35 .. 46 79 .. 45 80 .. 0.95 3 ! 17.7 0.0 6.3e-06 0.0039 3 35 .. 87 119 .. 85 120 .. 0.94 4 ! 22.5 0.0 1.8e-07 0.00011 1 35 [. 125 159 .. 125 160 .. 0.96 5 ! 16.4 0.0 1.6e-05 0.01 2 35 .. 166 199 .. 165 200 .. 0.95 6 ! 16.9 0.0 1.1e-05 0.007 1 35 [. 205 239 .. 205 240 .. 0.93 7 ! 17.8 0.0 5.7e-06 0.0036 1 35 [. 245 279 .. 245 280 .. 0.96 8 ! 23.2 0.0 1e-07 6.5e-05 1 35 [. 285 319 .. 285 320 .. 0.96 9 ! 17.7 0.0 6e-06 0.0038 1 35 [. 325 359 .. 325 360 .. 0.93 10 ! 17.7 0.0 6.3e-06 0.0039 1 35 [. 365 399 .. 365 400 .. 0.96 11 ! 22.5 0.0 1.8e-07 0.00011 1 35 [. 405 439 .. 405 440 .. 0.96 12 ! 22.5 0.0 1.8e-07 0.00011 1 35 [. 445 479 .. 445 480 .. 0.96 13 ! 22.3 0.0 2.1e-07 0.00013 1 35 [. 485 519 .. 485 520 .. 0.96 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 2.8e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++++++y ++ d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 5 AYLNIGSAYKSQSDFLKAIECYEKSLNIAREAGDR 39 789****************************9998 PP == domain 2 score: 16.4 bits; conditional E-value: 1.6e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 46 YFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 79 579***************************9998 PP == domain 3 score: 17.7 bits; conditional E-value: 6.3e-06 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 ++L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 87 LSLGVAYDSQSDFPKAIECYEKSLNIAREAGDR 119 78***************************9998 PP == domain 4 score: 22.5 bits; conditional E-value: 1.8e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y +++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 125 AYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDR 159 789****************************9998 PP == domain 5 score: 16.4 bits; conditional E-value: 1.6e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 166 YFNLGMAYNSQSDFPKAIECYEKSLNIAREAGDR 199 579***************************9998 PP == domain 6 score: 16.9 bits; conditional E-value: 1.1e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +++ +y++++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 205 AYFNIGFAYESQRDFPKAIECYEKSLNIAREAGDR 239 67888999***********************9998 PP == domain 7 score: 17.8 bits; conditional E-value: 5.7e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y +++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 245 AYFNLEVAYNSQRDFPKAIECYEKSLNIAREAGDR 279 789****************************9998 PP == domain 8 score: 23.2 bits; conditional E-value: 1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y +++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 285 AYFNLGKAYKSQRDFSKAIEWYEKSLNIAREAGDR 319 789****************************9998 PP == domain 9 score: 17.7 bits; conditional E-value: 6e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +++ +y++++d+ +Ai++ye+ L++a++ +dr FUN_000341-T1 325 AYFNIGFAYESQRDFPKAIECYEKSLDIAREAGDR 359 67888999***********************9998 PP == domain 10 score: 17.7 bits; conditional E-value: 6.3e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 365 AYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 399 789****************************9998 PP == domain 11 score: 22.5 bits; conditional E-value: 1.8e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y +++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 405 AYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDR 439 789****************************9998 PP == domain 12 score: 22.5 bits; conditional E-value: 1.8e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y +++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 445 AYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDR 479 789****************************9998 PP == domain 13 score: 22.3 bits; conditional E-value: 2.1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y +++d+ +Ai++ye+ L +a++ +dr FUN_000341-T1 485 AYFNLGKAYKSQRDFPKAIECYEKSLNIAREAGDR 519 789****************************9998 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.2 1.6e-05 0.01 2 32 .. 4 34 .. 3 36 .. 0.92 2 ! 17.6 0.0 6.6e-06 0.0041 2 32 .. 44 74 .. 43 76 .. 0.93 3 ! 17.1 0.0 9.5e-06 0.0059 3 32 .. 85 114 .. 84 116 .. 0.91 4 ! 24.7 0.3 3.7e-08 2.3e-05 2 32 .. 124 154 .. 123 156 .. 0.93 5 ! 18.3 0.0 4e-06 0.0025 2 32 .. 164 194 .. 163 196 .. 0.93 6 ! 25.2 0.1 2.5e-08 1.6e-05 2 32 .. 204 234 .. 203 236 .. 0.93 7 ! 9.8 0.2 0.0022 1.4 13 32 .. 255 274 .. 244 276 .. 0.86 8 ! 24.9 0.4 3.1e-08 1.9e-05 2 32 .. 284 314 .. 283 316 .. 0.93 9 ! 25.5 0.1 1.9e-08 1.2e-05 2 32 .. 324 354 .. 323 356 .. 0.93 10 ! 18.6 0.1 3.2e-06 0.002 2 32 .. 364 394 .. 363 396 .. 0.93 11 ! 24.7 0.3 3.7e-08 2.3e-05 2 32 .. 404 434 .. 403 436 .. 0.93 12 ! 24.7 0.3 3.7e-08 2.3e-05 2 32 .. 444 474 .. 443 476 .. 0.93 13 ! 26.5 0.3 9.5e-09 5.9e-06 2 32 .. 484 514 .. 483 516 .. 0.93 14 ? 0.4 0.0 2.1 1.3e+03 19 28 .. 588 597 .. 587 598 .. 0.90 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 1.6e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ n G ay + d+ +A+e+yek+l ++ FUN_000341-T1 4 RAYLNIGSAYKSQSDFLKAIECYEKSLNIAR 34 699************************9875 PP == domain 2 score: 17.6 bits; conditional E-value: 6.6e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG ay + d+ +A+e+yek+l ++ FUN_000341-T1 44 DVYFNLGVAYNSQSDFPKAIECYEKSLNIAR 74 58*************************9875 PP == domain 3 score: 17.1 bits; conditional E-value: 9.5e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 ++ lG ay + d+ +A+e+yek+l ++ FUN_000341-T1 85 VYLSLGVAYDSQSDFPKAIECYEKSLNIAR 114 6888**********************9875 PP == domain 4 score: 24.7 bits; conditional E-value: 3.7e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG+ay + d+ +A+e+yek+l ++ FUN_000341-T1 124 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 154 69*************************9875 PP == domain 5 score: 18.3 bits; conditional E-value: 4e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG+ay + d+ +A+e+yek+l ++ FUN_000341-T1 164 DVYFNLGMAYNSQSDFPKAIECYEKSLNIAR 194 58*************************9875 PP == domain 6 score: 25.2 bits; conditional E-value: 2.5e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++n G ay+ + d+ +A+e+yek+l ++ FUN_000341-T1 204 RAYFNIGFAYESQRDFPKAIECYEKSLNIAR 234 69*************************9875 PP == domain 7 score: 9.8 bits; conditional E-value: 0.0022 TPR_2 13 klgdyeeAleayekAleldP 32 + d+ +A+e+yek+l ++ FUN_000341-T1 255 SQRDFPKAIECYEKSLNIAR 274 589*************9875 PP == domain 8 score: 24.9 bits; conditional E-value: 3.1e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG+ay + d+ +A+e+yek+l ++ FUN_000341-T1 284 RAYFNLGKAYKSQRDFSKAIEWYEKSLNIAR 314 69*************************9875 PP == domain 9 score: 25.5 bits; conditional E-value: 1.9e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++n G ay+ + d+ +A+e+yek+l ++ FUN_000341-T1 324 RAYFNIGFAYESQRDFPKAIECYEKSLDIAR 354 69*************************9976 PP == domain 10 score: 18.6 bits; conditional E-value: 3.2e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG ay + d+ +A+e+yek+l ++ FUN_000341-T1 364 KAYFNLGVAYNSQSDFPKAIECYEKSLNIAR 394 69*************************9875 PP == domain 11 score: 24.7 bits; conditional E-value: 3.7e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG+ay + d+ +A+e+yek+l ++ FUN_000341-T1 404 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 434 69*************************9875 PP == domain 12 score: 24.7 bits; conditional E-value: 3.7e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG+ay + d+ +A+e+yek+l ++ FUN_000341-T1 444 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 474 69*************************9875 PP == domain 13 score: 26.5 bits; conditional E-value: 9.5e-09 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG+ay + d+ +A+e+yek+l ++ FUN_000341-T1 484 RAYFNLGKAYKSQRDFPKAIECYEKSLNIAR 514 69*************************9875 PP == domain 14 score: 0.4 bits; conditional E-value: 2.1 TPR_2 19 eAleayekAl 28 +Aleay+kAl FUN_000341-T1 588 RALEAYNKAL 597 69*******9 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.3 9.2e-08 5.7e-05 2 32 .. 4 34 .. 3 35 .. 0.95 2 ! 17.8 0.0 6.1e-06 0.0038 3 32 .. 45 74 .. 44 75 .. 0.94 3 ! 15.2 0.0 4.1e-05 0.026 3 32 .. 85 114 .. 84 115 .. 0.94 4 ! 22.5 0.1 1.9e-07 0.00012 2 32 .. 124 154 .. 123 155 .. 0.95 5 ! 19.7 0.0 1.5e-06 0.00093 3 32 .. 165 194 .. 164 195 .. 0.94 6 ! 21.2 0.1 5e-07 0.00031 2 32 .. 204 234 .. 203 235 .. 0.95 7 ! 9.0 0.2 0.004 2.5 3 32 .. 245 274 .. 244 275 .. 0.88 8 ! 26.1 0.2 1.3e-08 8.2e-06 2 32 .. 284 314 .. 283 315 .. 0.95 9 ! 21.8 0.0 3e-07 0.00019 2 32 .. 324 354 .. 323 355 .. 0.95 10 ! 18.7 0.1 2.9e-06 0.0018 2 32 .. 364 394 .. 363 395 .. 0.95 11 ! 22.5 0.1 1.9e-07 0.00012 2 32 .. 404 434 .. 403 435 .. 0.95 12 ! 22.5 0.1 1.9e-07 0.00012 2 32 .. 444 474 .. 443 475 .. 0.95 13 ! 24.0 0.1 6.1e-08 3.8e-05 2 32 .. 484 514 .. 483 515 .. 0.95 14 ? -1.1 0.0 6.6 4.1e+03 3 14 .. 525 536 .. 524 539 .. 0.75 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 9.2e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+n+G++y+++ d+ +A+e+yek+l +++ FUN_000341-T1 4 RAYLNIGSAYKSQSDFLKAIECYEKSLNIAR 34 89*************************9987 PP == domain 2 score: 17.8 bits; conditional E-value: 6.1e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y+nlG +y ++ d+ +A+e+yek+l +++ FUN_000341-T1 45 VYFNLGVAYNSQSDFPKAIECYEKSLNIAR 74 8*************************9987 PP == domain 3 score: 15.2 bits; conditional E-value: 4.1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y+ lG +y ++ d+ +A+e+yek+l +++ FUN_000341-T1 85 VYLSLGVAYDSQSDFPKAIECYEKSLNIAR 114 89************************9987 PP == domain 4 score: 22.5 bits; conditional E-value: 1.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y+++ d+ +A+e+yek+l +++ FUN_000341-T1 124 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 154 89*************************9987 PP == domain 5 score: 19.7 bits; conditional E-value: 1.5e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y+nlG++y ++ d+ +A+e+yek+l +++ FUN_000341-T1 165 VYFNLGMAYNSQSDFPKAIECYEKSLNIAR 194 8*************************9987 PP == domain 6 score: 21.2 bits; conditional E-value: 5e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+n+G +y+++ d+ +A+e+yek+l +++ FUN_000341-T1 204 RAYFNIGFAYESQRDFPKAIECYEKSLNIAR 234 89*************************9987 PP == domain 7 score: 9.0 bits; conditional E-value: 0.004 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay+nl +y ++ d+ +A+e+yek+l +++ FUN_000341-T1 245 AYFNLEVAYNSQRDFPKAIECYEKSLNIAR 274 6777778999****************9987 PP == domain 8 score: 26.1 bits; conditional E-value: 1.3e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y+++ d+ +A+e+yek+l +++ FUN_000341-T1 284 RAYFNLGKAYKSQRDFSKAIEWYEKSLNIAR 314 89*************************9987 PP == domain 9 score: 21.8 bits; conditional E-value: 3e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+n+G +y+++ d+ +A+e+yek+l++++ FUN_000341-T1 324 RAYFNIGFAYESQRDFPKAIECYEKSLDIAR 354 89**************************987 PP == domain 10 score: 18.7 bits; conditional E-value: 2.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y ++ d+ +A+e+yek+l +++ FUN_000341-T1 364 KAYFNLGVAYNSQSDFPKAIECYEKSLNIAR 394 69*************************9987 PP == domain 11 score: 22.5 bits; conditional E-value: 1.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y+++ d+ +A+e+yek+l +++ FUN_000341-T1 404 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 434 89*************************9987 PP == domain 12 score: 22.5 bits; conditional E-value: 1.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y+++ d+ +A+e+yek+l +++ FUN_000341-T1 444 RAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 474 89*************************9987 PP == domain 13 score: 24.0 bits; conditional E-value: 6.1e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y+++ d+ +A+e+yek+l +++ FUN_000341-T1 484 RAYFNLGKAYKSQRDFPKAIECYEKSLNIAR 514 89*************************9987 PP == domain 14 score: -1.1 bits; conditional E-value: 6.6 TPR_8 3 ayynlGliylkl 14 +y+ lG++y ++ FUN_000341-T1 525 VYFSLGNAYNSQ 536 799999999766 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.1 0.0017 1.1 4 35 .. 5 36 .. 3 36 .. 0.94 2 ! 11.8 0.0 0.00042 0.26 7 35 .. 48 76 .. 46 76 .. 0.96 3 ! 10.1 0.0 0.0015 0.93 5 35 .. 86 116 .. 84 116 .. 0.93 4 ! 14.7 0.0 5.2e-05 0.032 7 35 .. 128 156 .. 124 156 .. 0.94 5 ! 12.6 0.0 0.00024 0.15 7 35 .. 168 196 .. 166 196 .. 0.96 6 ! 10.1 0.0 0.0015 0.94 7 35 .. 208 236 .. 204 236 .. 0.93 7 ? 6.0 0.0 0.028 18 11 35 .. 252 276 .. 251 276 .. 0.93 8 ! 14.6 0.1 5.7e-05 0.036 7 35 .. 288 316 .. 284 316 .. 0.94 9 ! 11.4 0.0 0.00057 0.35 7 35 .. 328 356 .. 324 356 .. 0.94 10 ! 12.0 0.0 0.00036 0.22 7 35 .. 368 396 .. 365 396 .. 0.95 11 ! 14.7 0.0 5.2e-05 0.032 7 35 .. 408 436 .. 404 436 .. 0.94 12 ! 14.7 0.0 5.2e-05 0.032 7 35 .. 448 476 .. 444 476 .. 0.94 13 ! 12.8 0.0 0.00021 0.13 7 35 .. 488 516 .. 484 516 .. 0.94 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0017 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ n++ a+ +q ++ A e +e++l i++++ FUN_000341-T1 5 AYLNIGSAYKSQSDFLKAIECYEKSLNIAREA 36 899*************************9985 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00042 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++a+ +q ++ A e +e++l i++++ FUN_000341-T1 48 NLGVAYNSQSDFPKAIECYEKSLNIAREA 76 9************************9985 PP == domain 3 score: 10.1 bits; conditional E-value: 0.0015 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + L++a+ +q ++ A e +e++l i++++ FUN_000341-T1 86 YLSLGVAYDSQSDFPKAIECYEKSLNIAREA 116 789************************9985 PP == domain 4 score: 14.7 bits; conditional E-value: 5.2e-05 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ +q+++ A e++e++l i++++ FUN_000341-T1 128 NLGKAYKSQRDFPKAIEWYEKSLNIAREA 156 9************************9985 PP == domain 5 score: 12.6 bits; conditional E-value: 0.00024 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++a+ +q ++ A e +e++l i++++ FUN_000341-T1 168 NLGMAYNSQSDFPKAIECYEKSLNIAREA 196 9************************9985 PP == domain 6 score: 10.1 bits; conditional E-value: 0.0015 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 n++ a+ +q+++ A e +e++l i++++ FUN_000341-T1 208 NIGFAYESQRDFPKAIECYEKSLNIAREA 236 99***********************9985 PP == domain 7 score: 6.0 bits; conditional E-value: 0.028 TPR_10 11 alraqgryeeAeelleealairerv 35 a+ +q+++ A e +e++l i++++ FUN_000341-T1 252 AYNSQRDFPKAIECYEKSLNIAREA 276 899******************9985 PP == domain 8 score: 14.6 bits; conditional E-value: 5.7e-05 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ +q+++ A e++e++l i++++ FUN_000341-T1 288 NLGKAYKSQRDFSKAIEWYEKSLNIAREA 316 9************************9985 PP == domain 9 score: 11.4 bits; conditional E-value: 0.00057 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 n++ a+ +q+++ A e +e++l+i++++ FUN_000341-T1 328 NIGFAYESQRDFPKAIECYEKSLDIAREA 356 9************************9985 PP == domain 10 score: 12.0 bits; conditional E-value: 0.00036 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++a+ +q ++ A e +e++l i++++ FUN_000341-T1 368 NLGVAYNSQSDFPKAIECYEKSLNIAREA 396 9************************9985 PP == domain 11 score: 14.7 bits; conditional E-value: 5.2e-05 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ +q+++ A e++e++l i++++ FUN_000341-T1 408 NLGKAYKSQRDFPKAIEWYEKSLNIAREA 436 9************************9985 PP == domain 12 score: 14.7 bits; conditional E-value: 5.2e-05 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ +q+++ A e++e++l i++++ FUN_000341-T1 448 NLGKAYKSQRDFPKAIEWYEKSLNIAREA 476 9************************9985 PP == domain 13 score: 12.8 bits; conditional E-value: 0.00021 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ +q+++ A e +e++l i++++ FUN_000341-T1 488 NLGKAYKSQRDFPKAIECYEKSLNIAREA 516 9************************9985 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.7 1.3 1.1e-10 7e-08 41 180 .. 9 148 .. 3 148 .. 0.96 2 ! 39.0 2.0 1.4e-12 8.9e-10 42 180 .. 130 268 .. 123 268 .. 0.94 3 ! 42.6 3.4 1.1e-13 6.8e-11 44 180 .. 252 388 .. 245 399 .. 0.96 4 ! 34.9 0.9 2.5e-11 1.6e-08 42 142 .. 410 510 .. 404 517 .. 0.95 Alignments for each domain: == domain 1 score: 32.7 bits; conditional E-value: 1.1e-10 SNAP 41 AAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAi 135 + ayk + ++ +A e+++k ++ ++++++d + y++ +y+++ d +A+e++ek+ +i e+g + + + +++ y+++ +d+ kAi FUN_000341-T1 9 IGSAYKSQSDFLKAIECYEKSLNIAREAGDRDCEKDVYFNLGVAYNSQsDFPKAIECYEKSLNIAREAGDRDGEKDVYLSLGVAYDSQ-SDFPKAI 103 5789****************************************99875788************************************.******* PP SNAP 136 eaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e+Ye++ ++ ++ + + ++ ++ + + ++++++kAie yek FUN_000341-T1 104 ECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEK 148 *******************************************97 PP == domain 2 score: 39.0 bits; conditional E-value: 1.4e-12 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 ++ayk ++++ +A e ++k ++ ++++++d + y++ +y+++ d +A+e++ek+ +i e+g ++ ++ +++i+ ye++ d+ kAie FUN_000341-T1 130 GKAYKSQRDFPKAIEWYEKSLNIAREAGDRDGEKDVYFNLGMAYNSQsDFPKAIECYEKSLNIAREAGDRDTEGRAYFNIGFAYESQ-RDFPKAIE 224 789*****************************************9885788************************************.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 +Ye++ ++ ++ + +k++ ++ + ++++++kAie yek FUN_000341-T1 225 CYEKSLNIAREAGDRDGEKKAYFNLEVAYNSQRDFPKAIECYEK 268 ********9999998888888888877788999*********97 PP == domain 3 score: 42.6 bits; conditional E-value: 1.1e-13 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 ay ++++ +A e+++k ++ ++++++d ++ay++ k+yk++ d ++A+e +ek+ +i e+g ++ ++ +++i+ ye++ d+ kAie+Y FUN_000341-T1 252 AYNSQRDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQrDFSKAIEWYEKSLNIAREAGDRDTEGRAYFNIGFAYESQ-RDFPKAIECY 346 688999*************************************997899************************************.********** PP SNAP 139 eqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e++ d+ ++ + +k++ ++ + ++ +++kAie yek FUN_000341-T1 347 EKSLDIAREAGDRDGGKKAYFNLGVAYNSQSDFPKAIECYEK 388 *********999999*******99999**************7 PP == domain 4 score: 34.9 bits; conditional E-value: 2.5e-11 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 ++ayk ++++ +A e ++k ++ ++++++d ++ay++ k+yk++ d +A+e +ek+ +i e+g ++ ++ ++++++ y+++ d+ kAie FUN_000341-T1 410 GKAYKSQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQrDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQ-RDFPKAIE 504 789******************************************996788************************************.******** PP SNAP 137 aYeqAa 142 +Ye++ FUN_000341-T1 505 CYEKSL 510 ***976 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.064 40 2 25 .. 5 28 .. 4 32 .. 0.93 2 ? 7.8 0.0 0.014 8.4 1 25 [. 44 68 .. 44 72 .. 0.93 3 ? 4.7 0.0 0.13 79 1 25 [. 84 108 .. 84 112 .. 0.91 4 ? 5.8 0.0 0.058 36 2 21 .. 125 144 .. 124 151 .. 0.88 5 ! 8.5 0.0 0.0078 4.8 1 25 [. 164 188 .. 164 192 .. 0.93 6 ! 9.7 0.0 0.0032 2 2 25 .. 205 228 .. 204 232 .. 0.93 7 ? -0.6 0.0 6.4 4e+03 9 25 .. 252 268 .. 245 271 .. 0.84 8 ? 6.6 0.1 0.033 21 2 22 .. 285 305 .. 284 311 .. 0.88 9 ! 9.7 0.0 0.0033 2.1 2 25 .. 325 348 .. 324 352 .. 0.93 10 ! 8.2 0.0 0.01 6.2 2 25 .. 365 388 .. 364 392 .. 0.93 11 ? 5.8 0.0 0.058 36 2 21 .. 405 424 .. 404 431 .. 0.88 12 ? 5.8 0.0 0.058 36 2 21 .. 445 464 .. 444 471 .. 0.88 13 ! 10.6 0.0 0.0017 1.1 2 25 .. 485 508 .. 484 512 .. 0.93 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.064 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+l+++ +y+ + d+ +A++ +++ FUN_000341-T1 5 AYLNIGSAYKSQSDFLKAIECYEK 28 99********************98 PP == domain 2 score: 7.8 bits; conditional E-value: 0.014 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+++y + d+ +A++ +++ FUN_000341-T1 44 DVYFNLGVAYNSQSDFPKAIECYEK 68 789********************98 PP == domain 3 score: 4.7 bits; conditional E-value: 0.13 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++l l+++y + d+ +A++ +++ FUN_000341-T1 84 DVYLSLGVAYDSQSDFPKAIECYEK 108 68999******************98 PP == domain 4 score: 5.8 bits; conditional E-value: 0.058 TPR_6 2 AllklalsylelgdkdeAka 21 A+++l+++y+ + d+ +A++ FUN_000341-T1 125 AYFNLGKAYKSQRDFPKAIE 144 9*****************98 PP == domain 5 score: 8.5 bits; conditional E-value: 0.0078 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+++y + d+ +A++ +++ FUN_000341-T1 164 DVYFNLGMAYNSQSDFPKAIECYEK 188 789********************98 PP == domain 6 score: 9.7 bits; conditional E-value: 0.0032 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++++ +y+ + d+ +A++ +++ FUN_000341-T1 205 AYFNIGFAYESQRDFPKAIECYEK 228 9*********************98 PP == domain 7 score: -0.6 bits; conditional E-value: 6.4 TPR_6 9 sylelgdkdeAkaalqr 25 +y + d+ +A++ +++ FUN_000341-T1 252 AYNSQRDFPKAIECYEK 268 677799*********98 PP == domain 8 score: 6.6 bits; conditional E-value: 0.033 TPR_6 2 AllklalsylelgdkdeAkaa 22 A+++l+++y+ + d+ +A++ FUN_000341-T1 285 AYFNLGKAYKSQRDFSKAIEW 305 9*****************985 PP == domain 9 score: 9.7 bits; conditional E-value: 0.0033 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++++ +y+ + d+ +A++ +++ FUN_000341-T1 325 AYFNIGFAYESQRDFPKAIECYEK 348 9*********************98 PP == domain 10 score: 8.2 bits; conditional E-value: 0.01 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++l+++y + d+ +A++ +++ FUN_000341-T1 365 AYFNLGVAYNSQSDFPKAIECYEK 388 99********************98 PP == domain 11 score: 5.8 bits; conditional E-value: 0.058 TPR_6 2 AllklalsylelgdkdeAka 21 A+++l+++y+ + d+ +A++ FUN_000341-T1 405 AYFNLGKAYKSQRDFPKAIE 424 9*****************98 PP == domain 12 score: 5.8 bits; conditional E-value: 0.058 TPR_6 2 AllklalsylelgdkdeAka 21 A+++l+++y+ + d+ +A++ FUN_000341-T1 445 AYFNLGKAYKSQRDFPKAIE 464 9*****************98 PP == domain 13 score: 10.6 bits; conditional E-value: 0.0017 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++l+++y+ + d+ +A++ +++ FUN_000341-T1 485 AYFNLGKAYKSQRDFPKAIECYEK 508 9*********************98 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.0 0.0093 5.8 4 58 .. 10 70 .. 7 80 .. 0.70 2 ? 4.9 0.0 0.082 51 27 58 .. 77 110 .. 67 120 .. 0.75 3 ! 15.9 0.0 3e-05 0.018 3 58 .. 89 150 .. 87 160 .. 0.80 4 ? 5.8 0.0 0.044 28 30 58 .. 162 190 .. 150 200 .. 0.80 5 ? 7.1 0.0 0.018 11 3 58 .. 169 230 .. 167 240 .. 0.75 6 ? 3.5 0.0 0.23 1.4e+02 6 58 .. 212 270 .. 207 278 .. 0.74 7 ! 12.8 0.2 0.00029 0.18 10 58 .. 256 310 .. 251 320 .. 0.74 8 ? 5.7 0.0 0.049 31 30 61 .. 322 353 .. 307 357 .. 0.81 9 ! 14.5 0.0 8.4e-05 0.052 6 58 .. 332 390 .. 327 400 .. 0.87 10 ! 12.1 0.1 0.00048 0.3 30 58 .. 402 430 .. 388 439 .. 0.82 11 ! 12.1 0.1 0.00048 0.3 30 58 .. 442 470 .. 428 479 .. 0.82 12 ? 6.3 0.0 0.031 19 31 58 .. 483 510 .. 468 520 .. 0.76 13 ? 5.1 0.0 0.074 46 2 46 .. 488 538 .. 487 541 .. 0.67 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0093 TPR_16 4 araalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 + a+ + d+ A++++e l + +++lG+a+ q ++++A++ y++ l FUN_000341-T1 10 GSAYKSQSDFLKAIECYEKSLNIAreagdrDCEKDVYFNLGVAYNSQSDFPKAIECYEKSL 70 666666666666666665543222234466445689******************9998876 PP == domain 2 score: 4.9 bits; conditional E-value: 0.082 TPR_16 27 n..PeaaaAllglGlallrqgrlaeAaaayraal 58 + + +l lG+a+ q ++++A++ y++ l FUN_000341-T1 77 GdrDGEKDVYLSLGVAYDSQSDFPKAIECYEKSL 110 444446788999**************99998876 PP == domain 3 score: 15.9 bits; conditional E-value: 3e-05 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a+ + d++ A++++e l +A+++lG a+ q+++++A+++y++ l FUN_000341-T1 89 LGVAYDSQSDFPKAIECYEKSLNIAreagdrDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSL 150 778888999999999999875533334669977899**********************9987 PP == domain 4 score: 5.8 bits; conditional E-value: 0.044 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraal 58 + +++lG a+ q ++++A++ y++ l FUN_000341-T1 162 EKDVYFNLGMAYNSQSDFPKAIECYEKSL 190 67899*****************9998876 PP == domain 5 score: 7.1 bits; conditional E-value: 0.018 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a+ + d++ A++++e l +A+++ G a++ q+++++A++ y++ l FUN_000341-T1 169 LGMAYNSQSDFPKAIECYEKSLNIAreagdrDTEGRAYFNIGFAYESQRDFPKAIECYEKSL 230 677777788888888888765432223558866889*******************9998876 PP == domain 6 score: 3.5 bits; conditional E-value: 0.23 TPR_16 6 aalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 a+ ++d++ A++++e l A+++l +a+ q+++++A++ y++ l FUN_000341-T1 212 AYESQRDFPKAIECYEKSLNIAreagdrDGEKKAYFNLEVAYNSQRDFPKAIECYEKSL 270 56678888888888876543222355886788899999999999999999998887765 PP == domain 7 score: 12.8 bits; conditional E-value: 0.00029 TPR_16 10 agdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 ++d++ A++++e l +A+++lG a+ q+++ +A+++y++ l FUN_000341-T1 256 QRDFPKAIECYEKSLNIAreagdrDTEGRAYFNLGKAYKSQRDFSKAIEWYEKSL 310 56666666666554322223447766789**********************9987 PP == domain 8 score: 5.7 bits; conditional E-value: 0.049 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraalraa 61 +A+++ G a++ q+++++A++ y++ l++a FUN_000341-T1 322 EGRAYFNIGFAYESQRDFPKAIECYEKSLDIA 353 579********************999998765 PP == domain 9 score: 14.5 bits; conditional E-value: 8.4e-05 TPR_16 6 aalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 a+ ++d++ A++++e l+ A+++lG+a+ q ++++A++ y++ l FUN_000341-T1 332 AYESQRDFPKAIECYEKSLDIAreagdrDGGKKAYFNLGVAYNSQSDFPKAIECYEKSL 390 6778999*****99999988777888998899********************9998876 PP == domain 10 score: 12.1 bits; conditional E-value: 0.00048 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraal 58 +A+++lG a+ q+++++A+++y++ l FUN_000341-T1 402 EGRAYFNLGKAYKSQRDFPKAIEWYEKSL 430 579**********************9987 PP == domain 11 score: 12.1 bits; conditional E-value: 0.00048 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraal 58 +A+++lG a+ q+++++A+++y++ l FUN_000341-T1 442 EGRAYFNLGKAYKSQRDFPKAIEWYEKSL 470 579**********************9987 PP == domain 12 score: 6.3 bits; conditional E-value: 0.031 TPR_16 31 aaAllglGlallrqgrlaeAaaayraal 58 +A+++lG a+ q+++++A++ y++ l FUN_000341-T1 483 GRAYFNLGKAYKSQRDFPKAIECYEKSL 510 6788888888888888888888877765 PP == domain 13 score: 5.1 bits; conditional E-value: 0.074 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgr 46 l++a+ ++d++ A++++e l + ++ lG a+ q + FUN_000341-T1 488 NLGKAYKSQRDFPKAIECYEKSLNIAreagdrDGEKDVYFSLGNAYNSQSD 538 6899**************987542222344665566666666666666655 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.027 17 68 92 .. 15 39 .. 7 48 .. 0.84 2 ? 5.8 0.0 0.035 22 67 93 .. 54 80 .. 51 90 .. 0.84 3 ? 5.4 0.0 0.046 28 67 92 .. 94 119 .. 90 124 .. 0.88 4 ? 7.3 0.0 0.012 7.4 66 92 .. 134 159 .. 125 168 .. 0.83 5 ? 5.1 0.0 0.058 36 67 92 .. 174 199 .. 171 205 .. 0.88 6 ? 5.5 0.0 0.042 26 67 92 .. 214 239 .. 211 249 .. 0.87 7 ? 5.6 0.0 0.04 25 67 92 .. 254 279 .. 247 286 .. 0.88 8 ! 8.0 0.0 0.0071 4.4 66 92 .. 294 319 .. 284 325 .. 0.85 9 ? 5.7 0.0 0.037 23 67 91 .. 334 358 .. 331 367 .. 0.88 10 ? 5.1 0.0 0.057 36 67 92 .. 374 399 .. 371 406 .. 0.88 11 ? 7.0 0.0 0.015 9.4 66 92 .. 414 439 .. 405 451 .. 0.86 12 ? 6.9 0.0 0.016 9.7 66 92 .. 454 479 .. 444 486 .. 0.85 13 ? 6.0 0.0 0.03 18 66 93 .. 494 520 .. 485 539 .. 0.83 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.027 DUF7018 68 vqkllekaidhyekslklieeavek 92 q ++ kai+ yeksl++++ea ++ FUN_000341-T1 15 SQSDFLKAIECYEKSLNIAREAGDR 39 699****************999776 PP == domain 2 score: 5.8 bits; conditional E-value: 0.035 DUF7018 67 dvqkllekaidhyekslklieeavekk 93 + q ++ kai+ yeksl++++ea ++ FUN_000341-T1 54 NSQSDFPKAIECYEKSLNIAREAGDRD 80 689******************998773 PP == domain 3 score: 5.4 bits; conditional E-value: 0.046 DUF7018 67 dvqkllekaidhyekslklieeavek 92 d q ++ kai+ yeksl++++ea ++ FUN_000341-T1 94 DSQSDFPKAIECYEKSLNIAREAGDR 119 78******************998665 PP == domain 4 score: 7.3 bits; conditional E-value: 0.012 DUF7018 66 kdvqkllekaidhyekslklieeavek 92 k q+++ kai++yeksl++++ea ++ FUN_000341-T1 134 K-SQRDFPKAIEWYEKSLNIAREAGDR 159 3.699*****************99776 PP == domain 5 score: 5.1 bits; conditional E-value: 0.058 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000341-T1 174 NSQSDFPKAIECYEKSLNIAREAGDR 199 689*****************998665 PP == domain 6 score: 5.5 bits; conditional E-value: 0.042 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q+++ kai+ yeksl++++ea ++ FUN_000341-T1 214 ESQRDFPKAIECYEKSLNIAREAGDR 239 689*****************999766 PP == domain 7 score: 5.6 bits; conditional E-value: 0.04 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q+++ kai+ yeksl++++ea ++ FUN_000341-T1 254 NSQRDFPKAIECYEKSLNIAREAGDR 279 78******************998665 PP == domain 8 score: 8.0 bits; conditional E-value: 0.0071 DUF7018 66 kdvqkllekaidhyekslklieeavek 92 k q+++ kai++yeksl++++ea ++ FUN_000341-T1 294 K-SQRDFSKAIEWYEKSLNIAREAGDR 319 3.699****************998665 PP == domain 9 score: 5.7 bits; conditional E-value: 0.037 DUF7018 67 dvqkllekaidhyekslklieeave 91 + q+++ kai+ yeksl++++ea + FUN_000341-T1 334 ESQRDFPKAIECYEKSLDIAREAGD 358 689*****************99865 PP == domain 10 score: 5.1 bits; conditional E-value: 0.057 DUF7018 67 dvqkllekaidhyekslklieeavek 92 + q ++ kai+ yeksl++++ea ++ FUN_000341-T1 374 NSQSDFPKAIECYEKSLNIAREAGDR 399 689*****************998665 PP == domain 11 score: 7.0 bits; conditional E-value: 0.015 DUF7018 66 kdvqkllekaidhyekslklieeavek 92 k q+++ kai++yeksl++++ea ++ FUN_000341-T1 414 K-SQRDFPKAIEWYEKSLNIAREAGDR 439 3.699****************998766 PP == domain 12 score: 6.9 bits; conditional E-value: 0.016 DUF7018 66 kdvqkllekaidhyekslklieeavek 92 k q+++ kai++yeksl++++ea ++ FUN_000341-T1 454 K-SQRDFPKAIEWYEKSLNIAREAGDR 479 3.699****************998665 PP == domain 13 score: 6.0 bits; conditional E-value: 0.03 DUF7018 66 kdvqkllekaidhyekslklieeavekk 93 k q+++ kai+ yeksl++++ea ++ FUN_000341-T1 494 K-SQRDFPKAIECYEKSLNIAREAGDRD 520 3.699*****************998773 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 3 1.9e+03 16 34 .] 6 24 .. 3 32 .. 0.60 2 ? 5.9 0.0 0.041 25 14 34 .] 44 64 .. 42 64 .. 0.93 3 ? 1.1 0.0 1.4 8.8e+02 14 34 .] 84 104 .. 82 104 .. 0.92 4 ? 6.5 0.0 0.027 17 14 34 .] 124 144 .. 120 144 .. 0.90 5 ? 6.2 0.0 0.032 20 14 34 .] 164 184 .. 162 184 .. 0.93 6 ? 4.0 0.0 0.17 1e+02 14 34 .] 204 224 .. 200 224 .. 0.90 7 ? 6.0 0.0 0.038 24 14 34 .] 284 304 .. 280 304 .. 0.90 8 ? 4.0 0.0 0.17 1e+02 14 34 .] 324 344 .. 320 344 .. 0.90 9 ? 6.4 0.0 0.029 18 14 34 .] 364 384 .. 362 384 .. 0.93 10 ? 6.5 0.0 0.027 17 14 34 .] 404 424 .. 400 424 .. 0.90 11 ? 6.5 0.0 0.027 17 14 34 .] 444 464 .. 440 464 .. 0.90 12 ? 6.5 0.0 0.027 17 14 34 .] 484 504 .. 480 504 .. 0.90 13 ? 0.8 0.0 1.8 1.1e+03 14 31 .. 524 541 .. 522 543 .. 0.85 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 3 TPR_17 16 yynLArlllnnGqleeAlq 34 y n + +++ + ++ +A++ FUN_000341-T1 6 YLNIGSAYKSQSDFLKAIE 24 5555555555555555543 PP == domain 2 score: 5.9 bits; conditional E-value: 0.041 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL++++ + ++ +A++ FUN_000341-T1 44 DVYFNLGVAYNSQSDFPKAIE 64 79***************9985 PP == domain 3 score: 1.1 bits; conditional E-value: 1.4 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y L++++ + ++ +A++ FUN_000341-T1 84 DVYLSLGVAYDSQSDFPKAIE 104 789**************9985 PP == domain 4 score: 6.5 bits; conditional E-value: 0.027 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+nL+ +++ + ++ +A++ FUN_000341-T1 124 RAYFNLGKAYKSQRDFPKAIE 144 69****************985 PP == domain 5 score: 6.2 bits; conditional E-value: 0.032 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y+nL++++ + ++ +A++ FUN_000341-T1 164 DVYFNLGMAYNSQSDFPKAIE 184 79***************9985 PP == domain 6 score: 4.0 bits; conditional E-value: 0.17 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+n +++++ + ++ +A++ FUN_000341-T1 204 RAYFNIGFAYESQRDFPKAIE 224 69****************985 PP == domain 7 score: 6.0 bits; conditional E-value: 0.038 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+nL+ +++ + ++ +A++ FUN_000341-T1 284 RAYFNLGKAYKSQRDFSKAIE 304 69**************99985 PP == domain 8 score: 4.0 bits; conditional E-value: 0.17 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+n +++++ + ++ +A++ FUN_000341-T1 324 RAYFNIGFAYESQRDFPKAIE 344 69****************985 PP == domain 9 score: 6.4 bits; conditional E-value: 0.029 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay+nL++++ + ++ +A++ FUN_000341-T1 364 KAYFNLGVAYNSQSDFPKAIE 384 69***************9985 PP == domain 10 score: 6.5 bits; conditional E-value: 0.027 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+nL+ +++ + ++ +A++ FUN_000341-T1 404 RAYFNLGKAYKSQRDFPKAIE 424 69****************985 PP == domain 11 score: 6.5 bits; conditional E-value: 0.027 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+nL+ +++ + ++ +A++ FUN_000341-T1 444 RAYFNLGKAYKSQRDFPKAIE 464 69****************985 PP == domain 12 score: 6.5 bits; conditional E-value: 0.027 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay+nL+ +++ + ++ +A++ FUN_000341-T1 484 RAYFNLGKAYKSQRDFPKAIE 504 69****************985 PP == domain 13 score: 0.8 bits; conditional E-value: 1.8 TPR_17 14 dayynLArlllnnGqlee 31 d+y+ L++++ + ++ + FUN_000341-T1 524 DVYFSLGNAYNSQSDFPK 541 79********99988766 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.1 0.0082 5.1 1 23 [. 10 32 .. 10 36 .. 0.93 2 ? 2.5 0.1 0.26 1.6e+02 29 39 .. 44 54 .. 43 57 .. 0.86 3 ! 9.5 0.0 0.0017 1.1 3 23 .. 52 72 .. 50 76 .. 0.90 4 ! 10.4 0.5 0.00089 0.55 3 41 .. 92 136 .. 90 136 .. 0.76 5 ! 8.8 0.1 0.0029 1.8 1 23 [. 130 152 .. 130 156 .. 0.94 6 ! 11.7 0.3 0.00036 0.23 1 39 [. 170 214 .. 170 216 .. 0.74 7 ? 3.9 0.1 0.095 59 8 23 .. 217 232 .. 212 235 .. 0.83 8 ! 10.1 0.5 0.0012 0.72 3 41 .. 252 296 .. 252 296 .. 0.77 9 ! 9.3 1.3 0.002 1.2 1 40 [. 290 335 .. 290 337 .. 0.76 10 ? 3.3 0.0 0.15 94 9 23 .. 338 352 .. 335 356 .. 0.87 11 ? 2.4 0.1 0.28 1.8e+02 30 39 .. 365 374 .. 364 377 .. 0.85 12 ! 13.5 0.7 9.9e-05 0.062 3 41 .. 372 416 .. 370 417 .. 0.80 13 ! 12.0 1.4 0.0003 0.18 1 41 [. 410 456 .. 410 456 .. 0.81 14 ! 12.4 1.1 0.00022 0.14 1 41 [. 450 496 .. 450 497 .. 0.82 15 ! 9.4 1.1 0.0018 1.1 1 26 [. 490 515 .. 490 537 .. 0.74 16 ? 0.6 0.1 1.1 6.7e+02 13 21 .. 589 597 .. 587 598 .. 0.89 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0082 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay +q ++ +Aie+Y+k l++ FUN_000341-T1 10 GSAYKSQSDFLKAIECYEKSLNI 32 899****************9987 PP == domain 2 score: 2.5 bits; conditional E-value: 0.26 TPR_11 29 eayynLGlayy 39 ++y+nLG+ay FUN_000341-T1 44 DVYFNLGVAYN 54 79*******95 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0017 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +q ++++Aie+Y+k l++ FUN_000341-T1 52 AYNSQSDFPKAIECYEKSLNI 72 89***************9987 PP == domain 4 score: 10.4 bits; conditional E-value: 0.00089 TPR_11 3 ayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykq 41 ay +q ++++Aie+Y+k l++ + + ay+nLG+ay q FUN_000341-T1 92 AYDSQSDFPKAIECYEKSLNIAREAGDrdtegrAYFNLGKAYKSQ 136 5668999**************7665433333349*******9865 PP == domain 5 score: 8.8 bits; conditional E-value: 0.0029 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G+ay +q ++++Aie+Y+k l++ FUN_000341-T1 130 GKAYKSQRDFPKAIEWYEKSLNI 152 89*****************9987 PP == domain 6 score: 11.7 bits; conditional E-value: 0.00036 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayy 39 G ay +q ++++Aie+Y+k l++ + + ay+n+G+ay FUN_000341-T1 170 GMAYNSQSDFPKAIECYEKSLNIAREAGDrdtegrAYFNIGFAYE 214 569*******************96654333333338888888886 PP == domain 7 score: 3.9 bits; conditional E-value: 0.095 TPR_11 8 GkyeeAieaYkkAlkl 23 ++++Aie+Y+k l++ FUN_000341-T1 217 RDFPKAIECYEKSLNI 232 5799********9987 PP == domain 8 score: 10.1 bits; conditional E-value: 0.0012 TPR_11 3 ayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykq 41 ay +q ++++Aie+Y+k l++ + + ay+nLG+ay q FUN_000341-T1 252 AYNSQRDFPKAIECYEKSLNIAREAGDrdtegrAYFNLGKAYKSQ 296 68888899*************7665433333349*******9865 PP == domain 9 score: 9.3 bits; conditional E-value: 0.002 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayyk 40 G+ay +q ++ +Aie+Y+k l++ + + ay+n+G+ay FUN_000341-T1 290 GKAYKSQRDFSKAIEWYEKSLNIAREAGDrdtegrAYFNIGFAYES 335 89********************966543333333388888888865 PP == domain 10 score: 3.3 bits; conditional E-value: 0.15 TPR_11 9 kyeeAieaYkkAlkl 23 ++++Aie+Y+k l++ FUN_000341-T1 338 DFPKAIECYEKSLDI 352 689********9987 PP == domain 11 score: 2.4 bits; conditional E-value: 0.28 TPR_11 30 ayynLGlayy 39 ay+nLG+ay FUN_000341-T1 365 AYFNLGVAYN 374 9*******95 PP == domain 12 score: 13.5 bits; conditional E-value: 9.9e-05 TPR_11 3 ayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykq 41 ay +q ++++Aie+Y+k l++ + + ay+nLG+ay q FUN_000341-T1 372 AYNSQSDFPKAIECYEKSLNIAREAGDrdtegrAYFNLGKAYKSQ 416 89*******************7765433333349*******9865 PP == domain 13 score: 12.0 bits; conditional E-value: 0.0003 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykq 41 G+ay +q ++++Aie+Y+k l++ + + ay+nLG+ay q FUN_000341-T1 410 GKAYKSQRDFPKAIEWYEKSLNIAREAGDrdtegrAYFNLGKAYKSQ 456 89*********************7765433333349*******9865 PP == domain 14 score: 12.4 bits; conditional E-value: 0.00022 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykq 41 G+ay +q ++++Aie+Y+k l++ + + ay+nLG+ay q FUN_000341-T1 450 GKAYKSQRDFPKAIEWYEKSLNIAREAGDrdtegrAYFNLGKAYKSQ 496 89*********************7765433333349*******9865 PP == domain 15 score: 9.4 bits; conditional E-value: 0.0018 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPd 26 G+ay +q ++++Aie+Y+k l++ + FUN_000341-T1 490 GKAYKSQRDFPKAIECYEKSLNIARE 515 89*******************99655 PP == domain 16 score: 0.6 bits; conditional E-value: 1.1 TPR_11 13 AieaYkkAl 21 A+eaY+kAl FUN_000341-T1 589 ALEAYNKAL 597 9*******8 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.0 0.00079 0.49 40 115 .. 43 118 .. 4 123 .. 0.82 2 ! 14.6 0.0 3.4e-05 0.021 40 155 .. 123 236 .. 118 240 .. 0.87 3 ! 14.1 0.0 4.8e-05 0.03 13 155 .. 175 316 .. 173 321 .. 0.87 4 ! 12.6 0.0 0.00014 0.087 12 114 .. 254 357 .. 251 361 .. 0.87 5 ! 11.2 0.0 0.00036 0.23 13 116 .. 295 399 .. 290 404 .. 0.89 6 ! 14.1 0.0 4.8e-05 0.03 40 116 .. 363 439 .. 330 443 .. 0.82 7 ! 26.0 0.0 1.1e-08 7.1e-06 12 155 .. 374 516 .. 371 529 .. 0.92 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00079 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqeskl 115 ++++lG+a+ q d+ +A + +++ +ar+a++ + +l+++ + q ++ +A+e y++ l a+e++ FUN_000341-T1 43 KDVYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDRDGEKDVYLSLGVAYDSQSDFPKAIECYEKSLNIAREAGD 118 56789********************************99999999************************9999876 PP == domain 2 score: 14.6 bits; conditional E-value: 3.4e-05 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 + a+++lG a+ q d+ +A +++++ +ar+a++ + + +++ + q ++ +A+e y++ l a+e++ + + g ++ + + + FUN_000341-T1 123 GRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDRDGEKDVYFNLGMAYNSQSDFPKAIECYEKSLNIAREAGDRD--TEGRAYFNIGFAYESQ 216 5689***********************************9999*******************************9997..5556666667777778 PP TPR_MalT 136 ndLeeAeqhlqqgiqlgrql 155 d+ +A ++ +++++++r++ FUN_000341-T1 217 RDFPKAIECYEKSLNIAREA 236 88888888888888887765 PP == domain 3 score: 14.1 bits; conditional E-value: 4.8e-05 TPR_MalT 13 sqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 sq ++++a+e ++ L++ +e d + + a+++ G a+ q d+ +A + +++ +ar+a++ + a+ + + q ++ +A+e y++ l FUN_000341-T1 175 SQSDFPKAIECYEKSLNIAREAgDRDTEGRAYFNIGFAYESQRDFPKAIECYEKSLNIAREAGDRDGEKKAYFNLEVAYNSQRDFPKAIECYEKSL 270 57788888888888888887754667889999*****************************99999999999999999999999************ PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 a+e++ + + g ++ l++ + + d+ +A + +++++++r++ FUN_000341-T1 271 NIAREAGDRD--TEGRAYFNLGKAYKSQRDFSKAIEWYEKSLNIAREA 316 *****99996..678888899999999999999999999999999986 PP == domain 4 score: 12.6 bits; conditional E-value: 0.00014 TPR_MalT 12 vsqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 sq ++++a+e ++ L++ +e d + + a+++lG a+ q d+++A +++++ +ar+a++ + a+ + ++ q ++ +A+e y++ FUN_000341-T1 254 NSQRDFPKAIECYEKSLNIAREAgDRDTEGRAYFNLGKAYKSQRDFSKAIEWYEKSLNIAREAGDRDTEGRAYFNIGFAYESQRDFPKAIECYEKS 349 578889999999999999988754667889999***************************9999999888899999999999999999*****999 PP TPR_MalT 107 lqlaqesk 114 l a+e++ FUN_000341-T1 350 LDIAREAG 357 99999875 PP == domain 5 score: 11.2 bits; conditional E-value: 0.00036 TPR_MalT 13 sqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 sq ++ +a+e ++ L++ +e d + + a+++ G a+ q d+ +A + +++ +ar+a++ + a+ ++ + q ++ +A+e y++ l FUN_000341-T1 295 SQRDFSKAIEWYEKSLNIAREAgDRDTEGRAYFNIGFAYESQRDFPKAIECYEKSLDIAREAGDRDGGKKAYFNLGVAYNSQSDFPKAIECYEKSL 390 677888888888888888877535678899****************************************************************** PP TPR_MalT 108 qlaqeskle 116 a+e++ + FUN_000341-T1 391 NIAREAGDR 399 ***998765 PP == domain 6 score: 14.1 bits; conditional E-value: 4.8e-05 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqeskle 116 a+++lG+a+ q d+ +A + +++ +ar+a++ + a+ +++ + q ++ +A+e+y++ l a+e++ + FUN_000341-T1 363 KKAYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDR 439 4689**********************************99*******************************998765 PP == domain 7 score: 26.0 bits; conditional E-value: 1.1e-08 TPR_MalT 12 vsqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 sq ++++a+e ++ L++ +e d + + a+++lG a+ q d+ +A +++++ +ar+a++ + a+ +++ + q ++ +A+e+y++ FUN_000341-T1 374 NSQSDFPKAIECYEKSLNIAREAgDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKS 469 578899999999999999998864668889*************************************99*************************** PP TPR_MalT 107 lqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 l a+e++ + + g ++ l++ + + d+ +A ++ +++++++r++ FUN_000341-T1 470 LNIAREAGDRD--TEGRAYFNLGKAYKSQRDFPKAIECYEKSLNIAREA 516 *********97..7789999*************************9987 PP >> Glyco_trans_1_4 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.3 0.0 4.3e-22 2.7e-19 4 138 .. 1666 1810 .. 1663 1813 .. 0.79 Alignments for each domain: == domain 1 score: 70.3 bits; conditional E-value: 4.3e-22 Glyco_trans_1_4 4 ilfvGrl.ae..nekgvdllleavplvrkkerdvrlvivGdgpeeeeeleelak..gledr...veftGfvedlaellaaadvfvlPslseg 87 +l +Gr +e + kg d+ + av++++++e+ ++lv+vG +eeel+e+ +++ r v+ ++e+la+ + +ad++++Ps++eg FUN_000341-T1 1666 VLVFGRGdSEdfQLKGYDIAACAVAKLKDEEHPFKLVFVGAPAGKEEELKERFLlqDISRRqltVRRAKKREELAQQFYEADLVIMPSRTEG 1757 67778875557889**************88448*******433455799995544566544323555555599******************* PP Glyco_trans_1_4 88 fglkllEAmaaglPvVatdvggipevvedg..engllvppgdpealaeailrl 138 fgl++lEA++aglPv +++ +g+ ++e+ + ++v+++dp+++a+ai+r+ FUN_000341-T1 1758 FGLAALEALSAGLPVLVSSNSGLGVALEKVpfGTNFVVNSEDPTEWAKAIRRV 1810 ***************99988786665554444456***************986 PP >> Glycos_transf_1 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.0 0.0 7.8e-22 4.9e-19 27 158 .. 1679 1813 .. 1652 1830 .. 0.81 Alignments for each domain: == domain 1 score: 69.0 bits; conditional E-value: 7.8e-22 Glycos_transf_1 27 eKgldlllkafaklkeklkpdlklviaG..dgeeekklkklaeklglednvkflgfvs.dedlpellkiadvfvlpsrsEgfGivllEAmaa 115 Kg+d + a+aklk++ ++++klv++G g+e ++lk++ + ++ ++ + + + +e+l + + ad++++psr+EgfG+++lEA++a FUN_000341-T1 1679 LKGYDIAACAVAKLKDE-EHPFKLVFVGapAGKE-EELKERFLLQDISRRQLTVRRAKkREELAQQFYEADLVIMPSRTEGFGLAALEALSA 1768 39************986.**********975555.555555555555555555555554********************************* PP Glycos_transf_1 116 glpviasdvgglrevvkdge..tGllvkpnnaealaeaieklled 158 glpv++s ++gl +++ t ++v ++++ ++a+ai+++ ++ FUN_000341-T1 1769 GLPVLVSSNSGLGVALEKVPfgTNFVVNSEDPTEWAKAIRRVRSK 1813 ********9999999987666799****************98665 PP >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.0 2.3 6.3e-20 3.9e-17 1 142 [] 1000 1160 .. 1000 1160 .. 0.89 Alignments for each domain: == domain 1 score: 63.0 bits; conditional E-value: 6.3e-20 COR-A 1 Pkswlevreelee.kkseknyisleeyreicke.nglkeeeeqdrllkfLhdlGvllyfqddeelkdlviLkpeWlteavykvlds........ 84 P +wl++++ l+ + + +++i++e+ ++i++e +++++ +e ++l+fLhd l++f+d++el++lv+L+p+Wl+++ +v++ FUN_000341-T1 1000 PIKWLKYEKVLKVvQGQGRKCITIEHAKRIASEvCQIHDLQEFVTVLDFLHDQRILIHFDDNDELNNLVVLDPQWLIDVFKTVITVkrydhkew 1093 899*********9899**************98658**************************************************988888888 PP COR-A 85 .....kevlkkkGllkeedlkkiwkek.ypaeehdellrlmekfelcyelek...eeedtylvpqlL 142 l+++G+l+ee l++ w + +++ ++l+ +mekf l + ++ ++++ylvp++L FUN_000341-T1 1094 rfkdlWLKLEREGILEEELLQHAWGQMiDEHHTFESLIAIMEKFSLLCSWSSsdePRSKKYLVPSML 1160 774432335667**************9777777899**********99988876667799****987 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.23 1.4e+02 5 65 .. 13 79 .. 9 81 .. 0.61 2 ? 7.3 0.0 0.011 6.7 5 57 .. 93 144 .. 89 160 .. 0.86 3 ! 9.0 0.0 0.0033 2.1 5 66 .. 173 240 .. 169 241 .. 0.85 4 ! 10.5 0.0 0.0011 0.67 3 57 .. 251 304 .. 249 321 .. 0.85 5 ? 6.7 0.1 0.016 10 31 66 .. 325 360 .. 322 361 .. 0.87 6 ! 8.1 0.0 0.0062 3.8 4 57 .. 372 424 .. 369 441 .. 0.85 7 ? 5.8 0.0 0.033 20 3 57 .. 411 464 .. 409 482 .. 0.85 8 ? 6.1 0.0 0.025 15 3 57 .. 451 504 .. 449 520 .. 0.72 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.23 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 y ++ d+ +a++++e l + + + + +++ G +y + ++ +A+++ e+ l +a +a d+ FUN_000341-T1 13 YKSQSDFLKAIECYEKSLNIareagdRDCEKDVYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDR 79 5566666666666666666644333222233446777778888888888888888777777777766 PP == domain 2 score: 7.3 bits; conditional E-value: 0.011 TPR_9 5 yireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 y ++ d+++a++++e l +a +++++r G++y++lg ++ +d+ ++++ FUN_000341-T1 93 YDSQSDFPKAIECYEKSLNIA-REAGDRDTEGRAYFNLGKAYKSQRDFPKAIE 144 66899***************6.99****************9999999987775 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0033 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 y ++ d+++a++++e l + + + + +++ G++y+ ++++ +A+++ e+ l +a +a d++ FUN_000341-T1 173 YNSQSDFPKAIECYEKSLNIareagdRDTEGRAYFNIGFAYESQRDFPKAIECYEKSLNIAREAGDRD 240 6788999999999999999977766656667899999*******************999999998876 PP == domain 4 score: 10.5 bits; conditional E-value: 0.0011 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y +++d+++a++++e l +a +++++r G++y++lg ++ +d+ ++++ FUN_000341-T1 251 VAYNSQRDFPKAIECYEKSLNIA-REAGDRDTEGRAYFNLGKAYKSQRDFSKAIE 304 568899****************6.99****************9999999999885 PP == domain 5 score: 6.7 bits; conditional E-value: 0.016 TPR_9 31 errdrGllyaqlgcleaAladLeaylalapdapdae 66 +++ G++y+ ++++ +A+++ e+ l++a +a d++ FUN_000341-T1 325 AYFNIGFAYESQRDFPKAIECYEKSLDIAREAGDRD 360 577889999999999999999999999999998876 PP == domain 6 score: 8.1 bits; conditional E-value: 0.0062 TPR_9 4 iyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y ++ d+++a++++e l +a +++++r G++y++lg ++ +d+ ++++ FUN_000341-T1 372 AYNSQSDFPKAIECYEKSLNIA-REAGDRDTEGRAYFNLGKAYKSQRDFPKAIE 424 678899***************6.99****************9999999988775 PP == domain 7 score: 5.8 bits; conditional E-value: 0.033 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y +++d+++a++ +e l +a +++++r G++y++lg ++ +d+ ++++ FUN_000341-T1 411 KAYKSQRDFPKAIEWYEKSLNIA-REAGDRDTEGRAYFNLGKAYKSQRDFPKAIE 464 67999****************96.99***************99999999988775 PP == domain 8 score: 6.1 bits; conditional E-value: 0.025 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y +++d+++a++ +e l +a +++++r G++y++lg ++ +d+ ++++ FUN_000341-T1 451 KAYKSQRDFPKAIEWYEKSLNIA-REAGDRDTEGRAYFNLGKAYKSQRDFPKAIE 504 56888999999999999999995.7888888888888888877777777766654 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 5.2 3.2e+03 3 28 .. 5 30 .. 4 38 .. 0.86 2 ? 1.7 0.0 1.4 8.5e+02 3 28 .. 45 70 .. 43 78 .. 0.86 3 ? 2.2 0.0 0.97 6e+02 2 28 .. 84 110 .. 83 119 .. 0.88 4 ? 5.8 0.0 0.066 41 2 28 .. 124 150 .. 123 158 .. 0.88 5 ? 3.0 0.0 0.52 3.2e+02 3 29 .. 165 191 .. 163 199 .. 0.86 6 ? 4.2 0.0 0.22 1.4e+02 3 29 .. 205 231 .. 203 239 .. 0.84 7 ? 1.5 0.0 1.6 9.8e+02 9 28 .. 251 270 .. 244 278 .. 0.82 8 ? 6.7 0.0 0.034 21 2 28 .. 284 310 .. 283 319 .. 0.88 9 ? 4.8 0.0 0.14 89 3 30 .. 325 352 .. 323 359 .. 0.84 10 ? 2.1 0.0 1 6.4e+02 3 28 .. 365 390 .. 363 399 .. 0.87 11 ? 5.8 0.0 0.064 40 2 28 .. 404 430 .. 403 439 .. 0.88 12 ? 5.8 0.0 0.064 40 2 28 .. 444 470 .. 443 479 .. 0.88 13 ? 6.1 0.0 0.052 33 2 29 .. 484 511 .. 483 519 .. 0.88 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 5.2 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+l + a+ + d+ +A+e++e+ l FUN_000341-T1 5 AYLNIGSAYKSQSDFLKAIECYEKSL 30 7888999****************977 PP == domain 2 score: 1.7 bits; conditional E-value: 1.4 TPR_14 3 awlalarallalGdpdeAlelleral 28 ++ l+ a+ + d+ +A+e++e+ l FUN_000341-T1 45 VYFNLGVAYNSQSDFPKAIECYEKSL 70 5778999****************977 PP == domain 3 score: 2.2 bits; conditional E-value: 0.97 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +++l l+ a+ + d+ +A+e++e+ l FUN_000341-T1 84 DVYLSLGVAYDSQSDFPKAIECYEKSL 110 578999******************987 PP == domain 4 score: 5.8 bits; conditional E-value: 0.066 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+ l++a+ + d+ +A+e +e+ l FUN_000341-T1 124 RAYFNLGKAYKSQRDFPKAIEWYEKSL 150 57889*******************977 PP == domain 5 score: 3.0 bits; conditional E-value: 0.52 TPR_14 3 awlalarallalGdpdeAlellerala 29 ++ l+ a+ + d+ +A+e++e+ l FUN_000341-T1 165 VYFNLGMAYNSQSDFPKAIECYEKSLN 191 677899*****************9875 PP == domain 6 score: 4.2 bits; conditional E-value: 0.22 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+ + a++ + d+ +A+e++e+ l FUN_000341-T1 205 AYFNIGFAYESQRDFPKAIECYEKSLN 231 56667889***************9875 PP == domain 7 score: 1.5 bits; conditional E-value: 1.6 TPR_14 9 rallalGdpdeAlelleral 28 a+ + d+ +A+e++e+ l FUN_000341-T1 251 VAYNSQRDFPKAIECYEKSL 270 68999************977 PP == domain 8 score: 6.7 bits; conditional E-value: 0.034 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+ l++a+ + d+++A+e +e+ l FUN_000341-T1 284 RAYFNLGKAYKSQRDFSKAIEWYEKSL 310 57889*******************987 PP == domain 9 score: 4.8 bits; conditional E-value: 0.14 TPR_14 3 awlalarallalGdpdeAlelleralal 30 a+ + a++ + d+ +A+e++e+ l FUN_000341-T1 325 AYFNIGFAYESQRDFPKAIECYEKSLDI 352 56667889***************98875 PP == domain 10 score: 2.1 bits; conditional E-value: 1 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+ l+ a+ + d+ +A+e++e+ l FUN_000341-T1 365 AYFNLGVAYNSQSDFPKAIECYEKSL 390 6788999****************987 PP == domain 11 score: 5.8 bits; conditional E-value: 0.064 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+ l++a+ + d+ +A+e +e+ l FUN_000341-T1 404 RAYFNLGKAYKSQRDFPKAIEWYEKSL 430 57889*******************987 PP == domain 12 score: 5.8 bits; conditional E-value: 0.064 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+ l++a+ + d+ +A+e +e+ l FUN_000341-T1 444 RAYFNLGKAYKSQRDFPKAIEWYEKSL 470 57889*******************987 PP == domain 13 score: 6.1 bits; conditional E-value: 0.052 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+ l++a+ + d+ +A+e++e+ l FUN_000341-T1 484 RAYFNLGKAYKSQRDFPKAIECYEKSLN 511 57889*******************9875 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 1.6 9.8e+02 20 31 .. 18 29 .. 5 31 .. 0.81 2 ? 2.1 0.0 0.79 4.9e+02 18 31 .. 56 69 .. 44 71 .. 0.75 3 ? 1.5 0.0 1.2 7.4e+02 19 31 .. 97 109 .. 87 111 .. 0.84 4 ! 9.7 0.2 0.0031 1.9 3 31 .. 125 149 .. 123 151 .. 0.77 5 ? 2.3 0.0 0.65 4e+02 18 31 .. 176 189 .. 164 191 .. 0.71 6 ? 4.1 0.0 0.18 1.1e+02 18 31 .. 216 229 .. 203 231 .. 0.71 7 ? 3.0 0.0 0.4 2.5e+02 18 31 .. 256 269 .. 245 271 .. 0.87 8 ! 10.7 0.3 0.0015 0.92 3 31 .. 285 309 .. 283 311 .. 0.78 9 ? 4.2 0.0 0.16 1e+02 18 31 .. 336 349 .. 323 351 .. 0.71 10 ? 4.1 0.0 0.18 1.1e+02 2 31 .. 364 389 .. 363 391 .. 0.76 11 ! 9.7 0.2 0.0031 1.9 3 31 .. 405 429 .. 403 431 .. 0.77 12 ! 9.7 0.2 0.0031 1.9 3 31 .. 445 469 .. 443 471 .. 0.77 13 ? 5.3 0.1 0.073 45 3 31 .. 485 509 .. 483 511 .. 0.77 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 1.6 Sel1 20 DpekAlewyekA 31 D kA+e+yek+ FUN_000341-T1 18 DFLKAIECYEKS 29 999*******96 PP == domain 2 score: 2.1 bits; conditional E-value: 0.79 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000341-T1 56 QSDFPKAIECYEKS 69 35999*******96 PP == domain 3 score: 1.5 bits; conditional E-value: 1.2 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000341-T1 97 SDFPKAIECYEKS 109 4999*******96 PP == domain 4 score: 9.7 bits; conditional E-value: 0.0031 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG ++ +D kA+ewyek+ FUN_000341-T1 125 AYFNLGkA--YKS---QRDFPKAIEWYEKS 149 77777753..355...69**********96 PP == domain 5 score: 2.3 bits; conditional E-value: 0.65 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000341-T1 176 QSDFPKAIECYEKS 189 35999*******96 PP == domain 6 score: 4.1 bits; conditional E-value: 0.18 Sel1 18 pkDpekAlewyekA 31 +D kA+e+yek+ FUN_000341-T1 216 QRDFPKAIECYEKS 229 58**********96 PP == domain 7 score: 3.0 bits; conditional E-value: 0.4 Sel1 18 pkDpekAlewyekA 31 +D kA+e+yek+ FUN_000341-T1 256 QRDFPKAIECYEKS 269 58**********96 PP == domain 8 score: 10.7 bits; conditional E-value: 0.0015 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG ++ +D +kA+ewyek+ FUN_000341-T1 285 AYFNLGkA--YKS---QRDFSKAIEWYEKS 309 77777853..355...69**********96 PP == domain 9 score: 4.2 bits; conditional E-value: 0.16 Sel1 18 pkDpekAlewyekA 31 +D kA+e+yek+ FUN_000341-T1 336 QRDFPKAIECYEKS 349 58**********97 PP == domain 10 score: 4.1 bits; conditional E-value: 0.18 Sel1 2 eAqyrLGylylyGlgvpkDpekAlewyekA 31 +A+++LG +y + D kA+e+yek+ FUN_000341-T1 364 KAYFNLGVAY-NS---QSDFPKAIECYEKS 389 5888999433.44...469*********96 PP == domain 11 score: 9.7 bits; conditional E-value: 0.0031 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG ++ +D kA+ewyek+ FUN_000341-T1 405 AYFNLGkA--YKS---QRDFPKAIEWYEKS 429 77777753..355...69**********96 PP == domain 12 score: 9.7 bits; conditional E-value: 0.0031 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG ++ +D kA+ewyek+ FUN_000341-T1 445 AYFNLGkA--YKS---QRDFPKAIEWYEKS 469 77777753..355...69**********96 PP == domain 13 score: 5.3 bits; conditional E-value: 0.073 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG ++ +D kA+e+yek+ FUN_000341-T1 485 AYFNLGkA--YKS---QRDFPKAIECYEKS 509 77777753..355...69**********96 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.1 0.0099 6.2 135 174 .. 4 42 .. 4 45 .. 0.92 2 ? 2.2 0.0 0.32 2e+02 149 175 .. 57 83 .. 40 85 .. 0.82 3 ? 4.1 0.0 0.08 50 133 174 .. 62 122 .. 60 125 .. 0.68 4 ? 5.3 0.0 0.036 22 135 175 .. 124 163 .. 123 165 .. 0.92 5 ? 2.0 0.0 0.37 2.3e+02 147 174 .. 176 202 .. 164 205 .. 0.80 6 ? 6.1 0.0 0.021 13 135 175 .. 204 243 .. 203 245 .. 0.92 7 ? 3.4 0.0 0.14 85 136 174 .. 245 282 .. 244 284 .. 0.85 8 ? 4.9 0.1 0.046 29 135 174 .. 284 322 .. 283 324 .. 0.93 9 ? 4.5 0.0 0.062 39 135 172 .. 324 360 .. 323 365 .. 0.91 10 ? 2.8 0.0 0.21 1.3e+02 136 174 .. 365 402 .. 363 405 .. 0.81 11 ? 5.0 0.0 0.044 28 135 174 .. 404 442 .. 403 445 .. 0.92 12 ? 4.7 0.0 0.053 33 135 174 .. 444 482 .. 443 484 .. 0.93 13 ? 6.1 0.0 0.02 12 135 175 .. 484 523 .. 483 525 .. 0.92 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0099 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 +aYl++ + +++ +++a++++e++l +a+++g+r+ e FUN_000341-T1 4 RAYLNIGSAYKSQ-SDFLKAIECYEKSLNIAREAGDRDCE 42 69**********9.99*******************99865 PP == domain 2 score: 2.2 bits; conditional E-value: 0.32 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkeep 175 + +a++++e++l +a+++g+r+ e+ FUN_000341-T1 57 SDFPKAIECYEKSLNIAREAGDRDGEK 83 568899****************99876 PP == domain 3 score: 4.1 bits; conditional E-value: 0.08 DUF7380 133 AidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrkee 174 Ai++Y +s + +++ + +a++++e++l +a+++g+r++e FUN_000341-T1 62 AIECYEKSLNIAREAgdrdgekdvylslgvaydsQSDFPKAIECYEKSLNIAREAGDRDTE 122 5666644444444334446666666666666665578899999*********999999876 PP == domain 4 score: 5.3 bits; conditional E-value: 0.036 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 +aY + + +++ + + +a++++e++l +a+++g+r+ e+ FUN_000341-T1 124 RAYFNLGKAYKSQ-RDFPKAIEWYEKSLNIAREAGDRDGEK 163 5999999999999.99********************99876 PP == domain 5 score: 2.0 bits; conditional E-value: 0.37 DUF7380 147 gseewvdalkrleRAlqlaaqlgkrkee 174 + + +a++++e++l +a+++g+r++e FUN_000341-T1 176 Q-SDFPKAIECYEKSLNIAREAGDRDTE 202 4.568899****************9986 PP == domain 6 score: 6.1 bits; conditional E-value: 0.021 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 +aY ++ e++ + + +a++++e++l +a+++g+r+ e+ FUN_000341-T1 204 RAYFNIGFAYESQ-RDFPKAIECYEKSLNIAREAGDRDGEK 243 5999999999999.99********************99876 PP == domain 7 score: 3.4 bits; conditional E-value: 0.14 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aY + ++ + + +a++++e++l +a+++g+r++e FUN_000341-T1 245 AYFNLEVAYNSQ-RDFPKAIECYEKSLNIAREAGDRDTE 282 777777777777.8899******************9876 PP == domain 8 score: 4.9 bits; conditional E-value: 0.046 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 +aY + + +++ + +++a++++e++l +a+++g+r++e FUN_000341-T1 284 RAYFNLGKAYKSQ-RDFSKAIEWYEKSLNIAREAGDRDTE 322 5999999999999.99********************9876 PP == domain 9 score: 4.5 bits; conditional E-value: 0.062 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrk 172 +aY ++ e++ + + +a++++e++l +a+++g+r+ FUN_000341-T1 324 RAYFNIGFAYESQ-RDFPKAIECYEKSLDIAREAGDRD 360 5999999999999.99******************9987 PP == domain 10 score: 2.8 bits; conditional E-value: 0.21 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aY + ++ + +a++++e++l +a+++g+r++e FUN_000341-T1 365 AYFNLGVAYNSQ-SDFPKAIECYEKSLNIAREAGDRDTE 402 666666666666.77999*****************9986 PP == domain 11 score: 5.0 bits; conditional E-value: 0.044 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 +aY + + +++ + + +a++++e++l +a+++g+r++e FUN_000341-T1 404 RAYFNLGKAYKSQ-RDFPKAIEWYEKSLNIAREAGDRDTE 442 5999999999999.99********************9986 PP == domain 12 score: 4.7 bits; conditional E-value: 0.053 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 +aY + + +++ + + +a++++e++l +a+++g+r++e FUN_000341-T1 444 RAYFNLGKAYKSQ-RDFPKAIEWYEKSLNIAREAGDRDTE 482 5999999999999.99********************9876 PP == domain 13 score: 6.1 bits; conditional E-value: 0.02 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 +aY + + +++ + + +a++++e++l +a+++g+r+ e+ FUN_000341-T1 484 RAYFNLGKAYKSQ-RDFPKAIECYEKSLNIAREAGDRDGEK 523 5999999999999.99********************99876 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.0 2e-07 0.00012 2 41 .. 609 648 .. 608 700 .. 0.82 2 ! 27.5 0.1 6.5e-09 4.1e-06 39 91 .. 808 859 .. 785 906 .. 0.78 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 2e-07 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskel 41 ++l+G+++ GKtsl k + +f+++e+st+g+d + + FUN_000341-T1 609 IMLIGQERSGKTSLKKSLQGLQFNPNEDSTVGIDADPSYF 648 89********************************987654 PP == domain 2 score: 27.5 bits; conditional E-value: 6.5e-09 Roc 39 keltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.srs 91 kel+ ++++++++ +i +WD+aG+ ++++h+l+++++a+++lv+d sr+ FUN_000341-T1 808 KELQ--DKVDKRESEDDIYSVLWDFAGESVYYETHQLFLTSRAIYLLVYDlSRD 859 3332..344455556778889*****************************7553 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.1 0.46 2.9e+02 7 49 .. 21 69 .. 15 76 .. 0.74 2 ! 8.6 0.0 0.0053 3.3 3 71 .. 57 131 .. 55 134 .. 0.82 3 ? 6.0 0.0 0.035 22 2 50 .. 136 191 .. 135 210 .. 0.85 4 ? 3.7 0.0 0.18 1.1e+02 2 71 .. 216 291 .. 215 295 .. 0.72 5 ? 7.5 0.0 0.011 6.9 2 50 .. 256 311 .. 255 329 .. 0.77 6 ? 4.6 0.0 0.09 56 2 71 .. 336 411 .. 335 415 .. 0.73 7 ! 8.9 0.0 0.0043 2.7 2 71 .. 416 491 .. 415 495 .. 0.75 8 ? 5.1 0.0 0.064 40 2 71 .. 496 573 .. 495 575 .. 0.87 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.46 ANAPC3 7 nAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka 49 Ai ++e+ l a +++ ++d+y l+ ++ +++++ +A+e +k+ FUN_000341-T1 21 KAIECYEKSLniareAGDRDCEKDVYFnLGVAYNSQSDFPKAIECYEKS 69 68999999996665334444455566658****************9998 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0053 ANAPC3 3 hqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrkaklnekslgcryllAqcllkLkk 71 ++ Ai ++e+ l a +++ ++d+yl l+ ++ +++++ +A+e +k+ + + g r +++++ L+k FUN_000341-T1 57 SDFPKAIECYEKSLniareAGDRDGEKDVYLsLGVAYDSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGK 131 57789*********777766999999*****88********************5556666777777777777755 PP == domain 3 score: 6.0 bits; conditional E-value: 0.035 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka.k 50 ++++ Ai ++e+ l a +++ ++d+y l+ ++ +++++ +A+e +k+ + FUN_000341-T1 136 QRDFPKAIEWYEKSLniareAGDRDGEKDVYFnLGMAYNSQSDFPKAIECYEKSlN 191 678899*********7777668899999999978*****************99933 PP == domain 4 score: 3.7 bits; conditional E-value: 0.18 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrkaklnekslgcryllAqcllkLkk 71 ++++ Ai ++e+ l a +++ ++ ay l ++ ++ ++ +A+e +k+ + + g r +++++ L+k FUN_000341-T1 216 QRDFPKAIECYEKSLniareAGDRDGEKKAYFnLEVAYNSQRDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGK 291 5678889999999996666545666666666647888999999999999999995556666777777777776654 PP == domain 5 score: 7.5 bits; conditional E-value: 0.011 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka.k 50 ++++ Ai ++e+ l a +++++ ay l++++ ++ ++ +A+e+ +k+ + FUN_000341-T1 256 QRDFPKAIECYEKSLniareAGDRDTEGRAYFnLGKAYKSQRDFSKAIEWYEKSlN 311 6778899********6655334444444466558*****************99933 PP == domain 6 score: 4.6 bits; conditional E-value: 0.09 ANAPC3 2 nhqyknAiflaerll.....a.aepespedayllAqclflngqykrAyellrkaklnekslgcryllAqcllkLkk 71 ++++ Ai ++e+ l a + ++ + l+ ++ +++++ +A+e +k+ + + g r +++++ L+k FUN_000341-T1 336 QRDFPKAIECYEKSLdiareAgDRDGGKKAYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGK 411 6678899999999996655422444445556669******************995556666777777777777755 PP == domain 7 score: 8.9 bits; conditional E-value: 0.0043 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrkaklnekslgcryllAqcllkLkk 71 ++++ Ai ++e+ l a +++++ ay l++++ ++ ++ +A+e+ +k+ + + g r +++++ L+k FUN_000341-T1 416 QRDFPKAIEWYEKSLniareAGDRDTEGRAYFnLGKAYKSQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGK 491 678899*********6655434444454566658*******************95556666777777777777755 PP == domain 8 score: 5.1 bits; conditional E-value: 0.064 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngq..ykrAyellrkaklnekslgcryllAqcllkLkk 71 ++++ Ai ++e+ l a +++ ++d+y l++++ ++++ k+ +++ r+a+ ++ +++ y A+++l L++ FUN_000341-T1 496 QRDFPKAIECYEKSLniareAGDRDGEKDVYFsLGNAYNSQSDfpKKKSLNIAREAGDQGGVIRASYYVAESYLGLGN 573 678889*********7766557888888877758*********66699*************************98875 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.037 23 146 211 .. 14 78 .. 4 86 .. 0.66 2 ? 5.2 0.0 0.032 20 137 211 .. 45 118 .. 42 122 .. 0.72 3 ? 4.8 0.0 0.043 27 136 211 .. 84 158 .. 81 165 .. 0.74 4 ? 4.4 0.0 0.058 36 145 211 .. 133 198 .. 124 202 .. 0.69 5 ? 5.1 0.0 0.034 21 140 211 .. 168 238 .. 163 240 .. 0.60 6 ! 8.9 0.0 0.0024 1.5 138 211 .. 206 278 .. 203 282 .. 0.82 7 ? 1.5 0.0 0.45 2.8e+02 187 211 .. 294 318 .. 285 322 .. 0.87 8 ? 2.4 0.0 0.23 1.4e+02 186 211 .. 333 358 .. 325 360 .. 0.86 9 ? 3.9 0.0 0.083 52 144 211 .. 372 438 .. 362 443 .. 0.58 10 ? 2.8 0.0 0.17 1.1e+02 148 211 .. 416 478 .. 404 486 .. 0.58 11 ? 4.2 0.0 0.068 42 148 211 .. 456 518 .. 444 524 .. 0.64 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.037 ComR_TPR 146 lllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 + d+ k e+ +++ +i +++ d +k +++ l y + df kA e+Y+k++ a+ gd FUN_000341-T1 14 KSQSDFLKAIECYEKSLNIAREAGDRDcEKDVYFNLGVAYNS--QSDFPKAIECYEKSLNIAREAGD 78 444444444444555555555554433256777777777777..99999999999999999998887 PP == domain 2 score: 5.2 bits; conditional E-value: 0.032 ComR_TPR 137 vllsalavllllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 v++++ +++ + d+ k e+ +++ +i +++ d +k ++l l y + df kA e+Y+k++ a+ gd FUN_000341-T1 45 VYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDRDgEKDVYLSLGVAYDS--QSDFPKAIECYEKSLNIAREAGD 118 666666677777777777777777777777776654256677777777766..89999999999999999988877 PP == domain 3 score: 4.8 bits; conditional E-value: 0.043 ComR_TPR 136 dvllsalavllllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 dv+ls+ +++ + d+ k e+ +++ +i +++ d ++ k y ++df kA e Y+k++ a+ gd FUN_000341-T1 84 DVYLSLGVAYDSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYK-SQRDFPKAIEWYEKSLNIAREAGD 158 567777777777888888888888888888888777666655555555554.689999999999999999888777 PP == domain 4 score: 4.4 bits; conditional E-value: 0.058 ComR_TPR 145 llllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 + + d+ k e +++ +i +++ d +k +++ l y + df kA e+Y+k++ a+ gd FUN_000341-T1 133 YKSQRDFPKAIEWYEKSLNIAREAGDRDgEKDVYFNLGMAYNS--QSDFPKAIECYEKSLNIAREAGD 198 5555566666666666666666665543256677777777766..89999999999999999988887 PP == domain 5 score: 5.1 bits; conditional E-value: 0.034 ComR_TPR 140 salavllllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 ++ +++ + d+ k e+ +++ +i +++ d ++ ++ + ++df kA e+Y+k++ a+ gd FUN_000341-T1 168 NLGMAYNSQSDFPKAIECYEKSLNIAREAGDRDTE-GRAYFNIGFAYESQRDFPKAIECYEKSLNIAREAGD 238 55555555555555555555555555555554332.333344445555689999999999999999888777 PP == domain 6 score: 8.9 bits; conditional E-value: 0.0024 ComR_TPR 138 llsalavllllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 ++++ +++++ d+ k e+ +++ +i +++ d +k ++ le y ++df kA e+Y+k++ a+ gd FUN_000341-T1 206 YFNIGFAYESQRDFPKAIECYEKSLNIAREAGDRDgEKKAYFNLEVAYNS--QRDFPKAIECYEKSLNIAREAGD 278 5666777788888888888888888888888765437889999**99998..9****************999888 PP == domain 7 score: 1.5 bits; conditional E-value: 0.45 ComR_TPR 187 kvkkdfkkAkelYqkaimfakllgd 211 k ++df+kA e Y+k++ a+ gd FUN_000341-T1 294 KSQRDFSKAIEWYEKSLNIAREAGD 318 4689****************99888 PP == domain 8 score: 2.4 bits; conditional E-value: 0.23 ComR_TPR 186 lkvkkdfkkAkelYqkaimfakllgd 211 + ++df kA e+Y+k++ a+ gd FUN_000341-T1 333 YESQRDFPKAIECYEKSLDIAREAGD 358 45689****************99888 PP == domain 9 score: 3.9 bits; conditional E-value: 0.083 ComR_TPR 144 vllllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 ++ + d+ k e+ +++ +i +++ d ++ k y ++df kA e Y+k++ a+ gd FUN_000341-T1 372 AYNSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYK-SQRDFPKAIEWYEKSLNIAREAGD 438 4445555555555555555555555555444444443444443.577777777777777777776666 PP == domain 10 score: 2.8 bits; conditional E-value: 0.17 ComR_TPR 148 lkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 d+ k e +++ +i +++ d ++ k y ++df kA e Y+k++ a+ gd FUN_000341-T1 416 QRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYK-SQRDFPKAIEWYEKSLNIAREAGD 478 444444444455555555555444444333333333333.577788888888888777777666 PP == domain 11 score: 4.2 bits; conditional E-value: 0.068 ComR_TPR 148 lkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 d+ k e +++ +i +++ d ++ k y ++df kA e+Y+k++ a+ gd FUN_000341-T1 456 QRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYK-SQRDFPKAIECYEKSLNIAREAGD 518 555555555555666666666555544444444444443.689999999999999999988887 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.1 0.0031 1.9 87 142 .. 13 69 .. 3 76 .. 0.66 2 ! 9.4 0.1 0.0008 0.5 205 251 .. 103 149 .. 100 176 .. 0.88 3 ! 6.8 0.1 0.0051 3.2 92 142 .. 178 229 .. 157 238 .. 0.64 4 ! 12.9 2.6 7e-05 0.044 97 251 .. 263 429 .. 257 436 .. 0.67 5 ! 7.2 0.1 0.0038 2.4 85 142 .. 451 509 .. 429 515 .. 0.69 6 ? -3.9 0.1 8.4 5.3e+03 118 160 .. 646 688 .. 641 701 .. 0.81 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0031 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 y +++++a + ++k+l++a++ dr ++ y+n +++ d+ +ai+ yeks FUN_000341-T1 13 YKSQSDFLKAIECYEKSLNIAREAgDRDCEKDVYFNLGVAYNSQSDFPKAIECYEKS 69 555556666666677777776543366666777777777777777777777777766 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0008 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy + l+ a+e + + a + l++ y ++ ++ +ai+++ ++ FUN_000341-T1 103 IECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKS 149 68999999999999999999999********************9886 PP == domain 3 score: 6.8 bits; conditional E-value: 0.0051 TPR_IF140-IFT172 92 klyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 ++ +a + ++k+l++a++ dr ++y+n e+++d+ +ai+ yeks FUN_000341-T1 178 DFPKAIECYEKSLNIAREAgDRDTEGRAYFNIGFAYESQRDFPKAIECYEKS 229 5555555566666666543256666666666666666666666666666665 PP == domain 4 score: 12.9 bits; conditional E-value: 7e-05 TPR_IF140-IFT172 97 sgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaLe...syvkkskdkelkkWwaqyles... 182 + ++k+l++a++ dr ++y+n k +++d+++ai+ yeks e + ++ ++ +y ++++ ++ + + l+ FUN_000341-T1 263 IECYEKSLNIAREAgDRDTEGRAYFNLGKAYKSQRDFSKAIEWYEKSLNIAREAGDRDTEGRAYFNigfAYESQRDFPKAIECYEKSLDIare 355 566889999997643899999999999999999999999999999997666666555555555555111233333333333344444433111 PP TPR_IF140-IFT172 183 tgeletalkyy.eaaedylslv....rvlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 +g+ + +k y + y s+ + Cy + l+ a+e + + a + l++ y ++ ++ +ai+++ ++ FUN_000341-T1 356 AGDRDGGKKAYfNLGVAYNSQSdfpkAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKS 429 344555555551444455565422225788888888888888888888899*******************9875 PP == domain 5 score: 7.2 bits; conditional E-value: 0.0038 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 k y ++ +a + ++k+l++a++ dr ++y+n k +++d+ +ai+ yeks FUN_000341-T1 451 KAYKSQRDFPKAIEWYEKSLNIAREAgDRDTEGRAYFNLGKAYKSQRDFPKAIECYEKS 509 33444444445555566777777654388888889999999999999999999999998 PP == domain 6 score: -3.9 bits; conditional E-value: 8.4 TPR_IF140-IFT172 118 tyynyakhleakgdieeaiklyeksethrfevPrlLfddteaL 160 y++ + ++ ++g+ ++a+++ e + ++ + r++f++ ++ FUN_000341-T1 646 SYFKVTTEIWRTGKKDQAANKKETAAPYEHRLARVVFENLREQ 688 68889999999999999*********99*******99987654 PP >> Bleomycin_resist_prot_dom Bleomycin resistance protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 9.5 5.9e+03 7 33 .. 97 123 .. 90 128 .. 0.85 2 ? 3.6 0.0 0.19 1.2e+02 7 32 .. 137 162 .. 130 173 .. 0.87 3 ? -0.4 0.0 3.5 2.2e+03 7 41 .. 177 211 .. 170 219 .. 0.81 4 ? -1.7 0.0 8.6 5.4e+03 7 33 .. 257 283 .. 252 288 .. 0.88 5 ? 7.3 0.0 0.014 8.8 6 42 .. 296 332 .. 290 345 .. 0.83 6 ? -1.6 0.0 8.3 5.2e+03 7 33 .. 377 403 .. 370 408 .. 0.85 7 ? 5.5 0.0 0.051 32 7 34 .. 417 444 .. 410 456 .. 0.85 8 ? 5.7 0.0 0.045 28 7 35 .. 457 485 .. 450 504 .. 0.85 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 9.5 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeG 33 d k+++ +ek l + rd eG FUN_000341-T1 97 SDFPKAIECYEKSLNIAREAGDRDTEG 123 58899************9999***999 PP == domain 2 score: 3.6 bits; conditional E-value: 0.19 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivardde 32 +d k+++W+ek l + rd+e FUN_000341-T1 137 RDFPKAIEWYEKSLNIAREAGDRDGE 162 7999**********999999999998 PP == domain 3 score: -0.4 bits; conditional E-value: 3.5 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGlGdyGcvf 41 d k+++ +ek l + rd eG + f FUN_000341-T1 177 SDFPKAIECYEKSLNIAREAGDRDTEGRAYFNIGF 211 5899**********************987766555 PP == domain 4 score: -1.7 bits; conditional E-value: 8.6 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeG 33 +d k+++ +ek l + rd eG FUN_000341-T1 257 RDFPKAIECYEKSLNIAREAGDRDTEG 283 6899***************99***999 PP == domain 5 score: 7.3 bits; conditional E-value: 0.014 Bleomycin_resist_prot_dom 6 tkdmdktlkWfekilGWsGdivarddeGlGdyGcvfd 42 +d k+++W+ek l + rd eG + f FUN_000341-T1 296 QRDFSKAIEWYEKSLNIAREAGDRDTEGRAYFNIGFA 332 4799************************877665555 PP == domain 6 score: -1.6 bits; conditional E-value: 8.3 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeG 33 d k+++ +ek l + rd eG FUN_000341-T1 377 SDFPKAIECYEKSLNIAREAGDRDTEG 403 5899*************9999***999 PP == domain 7 score: 5.5 bits; conditional E-value: 0.051 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGl 34 +d k+++W+ek l + rd eG FUN_000341-T1 417 RDFPKAIEWYEKSLNIAREAGDRDTEGR 444 7999**********************96 PP == domain 8 score: 5.7 bits; conditional E-value: 0.045 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGlG 35 +d k+++W+ek l + rd eG FUN_000341-T1 457 RDFPKAIEWYEKSLNIAREAGDRDTEGRA 485 7999**********************965 PP >> VGCC_beta4Aa_N Voltage gated calcium channel subunit beta domain 4Aa N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.18 1.1e+02 15 38 .. 109 132 .. 107 134 .. 0.89 2 ? 4.5 0.0 0.081 50 15 38 .. 229 252 .. 227 254 .. 0.90 3 ? 3.4 0.0 0.18 1.1e+02 15 38 .. 269 292 .. 267 294 .. 0.89 4 ? 3.4 0.0 0.18 1.1e+02 15 38 .. 389 412 .. 387 414 .. 0.89 5 ? 3.4 0.0 0.18 1.1e+02 15 38 .. 429 452 .. 427 454 .. 0.89 6 ? 3.4 0.0 0.18 1.1e+02 15 38 .. 469 492 .. 467 494 .. 0.89 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.18 VGCC_beta4Aa_N 15 sLeedREaiRreaErqAllqLerA 38 sL+ REa r++E A L +A FUN_000341-T1 109 SLNIAREAGDRDTEGRAYFNLGKA 132 67778*****************99 PP == domain 2 score: 4.5 bits; conditional E-value: 0.081 VGCC_beta4Aa_N 15 sLeedREaiRreaErqAllqLerA 38 sL+ REa r+ E++A Le A FUN_000341-T1 229 SLNIAREAGDRDGEKKAYFNLEVA 252 67778****************987 PP == domain 3 score: 3.4 bits; conditional E-value: 0.18 VGCC_beta4Aa_N 15 sLeedREaiRreaErqAllqLerA 38 sL+ REa r++E A L +A FUN_000341-T1 269 SLNIAREAGDRDTEGRAYFNLGKA 292 67778*****************99 PP == domain 4 score: 3.4 bits; conditional E-value: 0.18 VGCC_beta4Aa_N 15 sLeedREaiRreaErqAllqLerA 38 sL+ REa r++E A L +A FUN_000341-T1 389 SLNIAREAGDRDTEGRAYFNLGKA 412 67778*****************99 PP == domain 5 score: 3.4 bits; conditional E-value: 0.18 VGCC_beta4Aa_N 15 sLeedREaiRreaErqAllqLerA 38 sL+ REa r++E A L +A FUN_000341-T1 429 SLNIAREAGDRDTEGRAYFNLGKA 452 67778*****************99 PP == domain 6 score: 3.4 bits; conditional E-value: 0.18 VGCC_beta4Aa_N 15 sLeedREaiRreaErqAllqLerA 38 sL+ REa r++E A L +A FUN_000341-T1 469 SLNIAREAGDRDTEGRAYFNLGKA 492 67778*****************99 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.66 4.1e+02 122 153 .] 39 70 .. 11 70 .. 0.73 2 ? -0.4 0.0 2.9 1.8e+03 130 153 .] 87 110 .. 79 114 .. 0.76 3 ? 4.2 0.0 0.11 67 5 29 .. 129 153 .. 126 161 .. 0.83 4 ? 0.8 0.0 1.2 7.3e+02 128 153 .] 165 190 .. 159 190 .. 0.83 5 ? 0.7 0.0 1.3 7.9e+02 134 153 .] 211 230 .. 206 236 .. 0.64 6 ? -0.3 0.1 2.5 1.6e+03 135 153 .] 252 270 .. 243 270 .. 0.84 7 ? 5.7 0.0 0.036 22 5 29 .. 289 313 .. 287 317 .. 0.83 8 ? 0.4 0.0 1.5 9.5e+02 133 153 .] 330 350 .. 326 354 .. 0.73 9 ? -0.2 0.0 2.5 1.5e+03 132 153 .] 369 390 .. 364 395 .. 0.66 10 ? 4.0 0.0 0.12 75 5 29 .. 409 433 .. 407 437 .. 0.82 11 ? 4.1 0.0 0.12 74 5 29 .. 449 473 .. 447 478 .. 0.82 12 ? 2.9 0.1 0.27 1.7e+02 131 153 .] 488 510 .. 484 516 .. 0.72 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.66 ARM_TT21_4th 122 kklaakiclqlAehaaserdyekaiklYkeAL 153 + + +++ ++l+ + s++d+ kai++Y +L FUN_000341-T1 39 RDCEKDVYFNLGVAYNSQSDFPKAIECYEKSL 70 45556778888899999999999999998765 PP == domain 2 score: -0.4 bits; conditional E-value: 2.9 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 l+l+ + s++d+ kai++Y +L FUN_000341-T1 87 LSLGVAYDSQSDFPKAIECYEKSL 110 566677788888888888887665 PP == domain 3 score: 4.2 bits; conditional E-value: 0.11 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ ++ kAi++Ye+ l++ FUN_000341-T1 129 LGKAYKSQRDFPKAIEWYEKSLNIA 153 7899999999999999999988765 PP == domain 4 score: 0.8 bits; conditional E-value: 1.2 ARM_TT21_4th 128 iclqlAehaaserdyekaiklYkeAL 153 + ++l+ + s++d+ kai++Y +L FUN_000341-T1 165 VYFNLGMAYNSQSDFPKAIECYEKSL 190 56778889999999999999998776 PP == domain 5 score: 0.7 bits; conditional E-value: 1.3 ARM_TT21_4th 134 ehaaserdyekaiklYkeAL 153 ++s+rd+ kai++Y +L FUN_000341-T1 211 FAYESQRDFPKAIECYEKSL 230 44566677777777776554 PP == domain 6 score: -0.3 bits; conditional E-value: 2.5 ARM_TT21_4th 135 haaserdyekaiklYkeAL 153 + s+rd+ kai++Y +L FUN_000341-T1 252 AYNSQRDFPKAIECYEKSL 270 57899**********9876 PP == domain 7 score: 5.7 bits; conditional E-value: 0.036 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi++Ye+ l++ FUN_000341-T1 289 LGKAYKSQRDFSKAIEWYEKSLNIA 313 7999999999999999999988765 PP == domain 8 score: 0.4 bits; conditional E-value: 1.5 ARM_TT21_4th 133 AehaaserdyekaiklYkeAL 153 + ++s+rd+ kai++Y +L FUN_000341-T1 330 GFAYESQRDFPKAIECYEKSL 350 445778888888888887665 PP == domain 9 score: -0.2 bits; conditional E-value: 2.5 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s++d+ kai++Y +L FUN_000341-T1 369 LGVAYNSQSDFPKAIECYEKSL 390 4555666777777777776554 PP == domain 10 score: 4.0 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ ++ kAi++Ye+ l++ FUN_000341-T1 409 LGKAYKSQRDFPKAIEWYEKSLNIA 433 6899999999999999999988765 PP == domain 11 score: 4.1 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ ++ kAi++Ye+ l++ FUN_000341-T1 449 LGKAYKSQRDFPKAIEWYEKSLNIA 473 6899999999999999999988765 PP == domain 12 score: 2.9 bits; conditional E-value: 0.27 ARM_TT21_4th 131 qlAehaaserdyekaiklYkeAL 153 +l++ + s+rd+ kai++Y +L FUN_000341-T1 488 NLGKAYKSQRDFPKAIECYEKSL 510 56677777777777777776654 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.9 1.8e+03 18 32 .. 17 31 .. 9 43 .. 0.84 2 ? 3.3 0.1 0.21 1.3e+02 9 33 .. 48 72 .. 46 84 .. 0.84 3 ? 7.4 0.0 0.011 6.8 10 33 .. 89 112 .. 86 125 .. 0.87 4 ? 0.5 0.0 1.5 9.2e+02 16 33 .. 135 152 .. 123 164 .. 0.82 5 ? 2.2 0.0 0.43 2.7e+02 12 33 .. 171 192 .. 166 204 .. 0.81 6 ? 4.8 0.1 0.069 43 8 33 .. 207 232 .. 201 252 .. 0.82 7 ? 2.0 0.0 0.53 3.3e+02 14 33 .. 253 272 .. 246 284 .. 0.84 8 ? 1.4 0.0 0.79 4.9e+02 16 32 .. 295 311 .. 281 324 .. 0.81 9 ? 5.1 0.0 0.056 35 8 33 .. 327 352 .. 321 360 .. 0.85 10 ? 4.0 0.0 0.12 76 7 33 .. 366 392 .. 364 405 .. 0.85 11 ? 0.6 0.0 1.4 8.5e+02 16 32 .. 415 431 .. 401 444 .. 0.80 12 ? 0.6 0.0 1.4 8.7e+02 16 32 .. 455 471 .. 442 484 .. 0.80 13 ? 1.5 0.0 0.72 4.5e+02 16 33 .. 495 512 .. 481 524 .. 0.81 14 ? -1.2 0.1 4.9 3.1e+03 14 36 .. 1823 1845 .. 1821 1848 .. 0.87 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.9 MIT 18 gnyeeAlelYkeale 32 ++ +A+e+Y+++l+ FUN_000341-T1 17 SDFLKAIECYEKSLN 31 56779******9997 PP == domain 2 score: 3.3 bits; conditional E-value: 0.21 MIT 9 kkAveeDnagnyeeAlelYkealel 33 + v + ++ ++ +A+e+Y+++l+ FUN_000341-T1 48 NLGVAYNSQSDFPKAIECYEKSLNI 72 5678888999***********9985 PP == domain 3 score: 7.4 bits; conditional E-value: 0.011 MIT 10 kAveeDnagnyeeAlelYkealel 33 v +D++ ++ +A+e+Y+++l+ FUN_000341-T1 89 LGVAYDSQSDFPKAIECYEKSLNI 112 5799****************9985 PP == domain 4 score: 0.5 bits; conditional E-value: 1.5 MIT 16 nagnyeeAlelYkealel 33 ++ ++ +A+e+Y+++l+ FUN_000341-T1 135 SQRDFPKAIEWYEKSLNI 152 5678999*******9975 PP == domain 5 score: 2.2 bits; conditional E-value: 0.43 MIT 12 veeDnagnyeeAlelYkealel 33 + + ++ ++ +A+e+Y+++l+ FUN_000341-T1 171 MAYNSQSDFPKAIECYEKSLNI 192 5667788999********9975 PP == domain 6 score: 4.8 bits; conditional E-value: 0.069 MIT 8 vkkAveeDnagnyeeAlelYkealel 33 ++ ++++ ++ +A+e+Y+++l+ FUN_000341-T1 207 FNIGFAYESQRDFPKAIECYEKSLNI 232 566678999**************986 PP == domain 7 score: 2.0 bits; conditional E-value: 0.53 MIT 14 eDnagnyeeAlelYkealel 33 + ++ ++ +A+e+Y+++l+ FUN_000341-T1 253 YNSQRDFPKAIECYEKSLNI 272 56778999********9975 PP == domain 8 score: 1.4 bits; conditional E-value: 0.79 MIT 16 nagnyeeAlelYkeale 32 ++ ++++A+e+Y+++l+ FUN_000341-T1 295 SQRDFSKAIEWYEKSLN 311 677999*******9997 PP == domain 9 score: 5.1 bits; conditional E-value: 0.056 MIT 8 vkkAveeDnagnyeeAlelYkealel 33 ++ ++++ ++ +A+e+Y+++l+ FUN_000341-T1 327 FNIGFAYESQRDFPKAIECYEKSLDI 352 566678999**************985 PP == domain 10 score: 4.0 bits; conditional E-value: 0.12 MIT 7 lvkkAveeDnagnyeeAlelYkealel 33 +++ v + ++ ++ +A+e+Y+++l+ FUN_000341-T1 366 YFNLGVAYNSQSDFPKAIECYEKSLNI 392 567789999999***********9985 PP == domain 11 score: 0.6 bits; conditional E-value: 1.4 MIT 16 nagnyeeAlelYkeale 32 ++ ++ +A+e+Y+++l+ FUN_000341-T1 415 SQRDFPKAIEWYEKSLN 431 5678999*****99997 PP == domain 12 score: 0.6 bits; conditional E-value: 1.4 MIT 16 nagnyeeAlelYkeale 32 ++ ++ +A+e+Y+++l+ FUN_000341-T1 455 SQRDFPKAIEWYEKSLN 471 5678999*****99997 PP == domain 13 score: 1.5 bits; conditional E-value: 0.72 MIT 16 nagnyeeAlelYkealel 33 ++ ++ +A+e+Y+++l+ FUN_000341-T1 495 SQRDFPKAIECYEKSLNI 512 577899********9975 PP == domain 14 score: -1.2 bits; conditional E-value: 4.9 MIT 14 eDnagnyeeAlelYkealelLlq 36 +D ++ny+e +++ k++ +lL + FUN_000341-T1 1823 SDLRKNYSETYNWEKQCSQLLEK 1845 6889*********9**9999976 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.65 4e+02 42 76 .. 7 41 .. 4 45 .. 0.82 2 ? 1.7 0.1 0.63 3.9e+02 18 73 .. 23 78 .. 15 85 .. 0.51 3 ? 1.7 0.0 0.61 3.8e+02 12 74 .. 57 119 .. 46 123 .. 0.63 4 ? 1.2 0.0 0.91 5.6e+02 12 73 .. 97 158 .. 91 163 .. 0.69 5 ? 1.7 0.0 0.61 3.8e+02 40 74 .. 165 199 .. 135 202 .. 0.71 6 ? 2.0 0.0 0.5 3.1e+02 11 73 .. 176 238 .. 166 241 .. 0.55 7 ? 4.2 0.1 0.1 64 10 74 .. 215 279 .. 206 282 .. 0.89 8 ? 2.9 0.0 0.26 1.6e+02 10 74 .. 255 319 .. 250 321 .. 0.85 9 ! 10.2 0.0 0.0014 0.88 10 75 .. 335 400 .. 326 403 .. 0.94 10 ? 0.8 0.0 1.2 7.5e+02 12 74 .. 417 479 .. 405 489 .. 0.68 11 ? 1.2 0.0 0.86 5.4e+02 12 74 .. 457 519 .. 446 521 .. 0.71 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.65 ANAPC5 42 lnlailhadfghneeAvkaieeaiklArenkDtac 76 ln + + + ++ +A++ e + ++Are +D c FUN_000341-T1 7 LNIGSAYKSQSDFLKAIECYEKSLNIAREAGDRDC 41 66666666667778999***************988 PP == domain 2 score: 1.7 bits; conditional E-value: 0.63 ANAPC5 18 ldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 +++ + ++ + ++ + + +nl + + + ++ +A++ e + ++Are +D FUN_000341-T1 23 IECYEKSLNIAREAGDRDCEKDVYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGD 78 33333333333333333333334445555555555555666666666666666665 PP == domain 3 score: 1.7 bits; conditional E-value: 0.61 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +d+++a+++ + ++ + ++ + l+l + + + ++ +A++ e + ++Are +D FUN_000341-T1 57 SDFPKAIECYEKSLNIAREAGDRDGEKDVYLSLGVAYDSQSDFPKAIECYEKSLNIAREAGDR 119 455555555555555555555555555556666666666666777777777788888887775 PP == domain 4 score: 1.2 bits; conditional E-value: 0.91 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 +d+++a+++ + ++ + ++ + a +nl + + + +A++ e + ++Are +D FUN_000341-T1 97 SDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGD 158 56666666666666666666666666667777777777777777777777888888888777 PP == domain 5 score: 1.7 bits; conditional E-value: 0.61 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDt 74 +nl + + + ++ +A++ e + ++Are +D FUN_000341-T1 165 VYFNLGMAYNSQSDFPKAIECYEKSLNIAREAGDR 199 56788888888888899999999999999999996 PP == domain 6 score: 2.0 bits; conditional E-value: 0.5 ANAPC5 11 akdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 ++d+++a+++ + ++ + ++ + a +n + + + +A++ e + ++Are +D FUN_000341-T1 176 QSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNIGFAYESQRDFPKAIECYEKSLNIAREAGD 238 445555555555555555555555555555555555555555556666666666666666666 PP == domain 7 score: 4.2 bits; conditional E-value: 0.1 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +++d+++a+++ + ++ + ++ + a +nl + + + + +A++ e + ++Are +D FUN_000341-T1 215 SQRDFPKAIECYEKSLNIAREAGDRDGEKKAYFNLEVAYNSQRDFPKAIECYEKSLNIAREAGDR 279 578999999999999999999999999999999999999999999****************9997 PP == domain 8 score: 2.9 bits; conditional E-value: 0.26 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +++d+++a+++ + ++ + ++ + a +nl + + + +A++ e + ++Are +D FUN_000341-T1 255 SQRDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFSKAIEWYEKSLNIAREAGDR 319 56788888888888888888888888888899999999999999999999999999999999996 PP == domain 9 score: 10.2 bits; conditional E-value: 0.0014 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 +++d+++a+++ + D++ + ++ + a +nl + + + ++ +A++ e + ++Are +D FUN_000341-T1 335 SQRDFPKAIECYEKSLDIAREAGDRDGGKKAYFNLGVAYNSQSDFPKAIECYEKSLNIAREAGDRD 400 689***********************************************************9975 PP == domain 10 score: 0.8 bits; conditional E-value: 1.2 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +d+++a++ + ++ + ++ + a +nl + + + +A++ e + ++Are +D FUN_000341-T1 417 RDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDR 479 555555555555555555555555555666666666666667777778888888888888775 PP == domain 11 score: 1.2 bits; conditional E-value: 0.86 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +d+++a++ + ++ + ++ + a +nl + + + +A++ e + ++Are +D FUN_000341-T1 457 RDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIECYEKSLNIAREAGDR 519 566666666666666666666666666677777777777777888888899999999998885 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.3 0.16 98 97 160 .. 5 74 .. 3 83 .. 0.62 2 ? 1.1 0.0 0.7 4.4e+02 134 161 .. 88 115 .. 78 119 .. 0.87 3 ? 6.5 0.1 0.015 9.3 129 172 .. 203 246 .. 196 251 .. 0.84 4 ! 12.6 0.9 0.0002 0.13 59 165 .. 247 359 .. 238 369 .. 0.84 5 ? 4.1 0.0 0.081 50 129 161 .. 363 395 .. 358 399 .. 0.89 6 ! 8.0 0.3 0.0053 3.3 57 161 .. 405 515 .. 391 521 .. 0.83 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.16 ARM_TT21_C 97 awLlladiyiqsgkldlAeeLlkkvlky.....nkscakA.yellGliaekeqsykdAaenYekAWklsk 160 a+L + y +++ + +A e +k l+ +++c k y lG+ +++++ + +A+e+Yek+ +++ FUN_000341-T1 5 AYLNIGSAYKSQSDFLKAIECYEKSLNIareagDRDCEKDvYFNLGVAYNSQSDFPKAIECYEKSLNIAR 74 5555555555555555555555555554222224567775255688888888888888888888877665 PP == domain 2 score: 1.1 bits; conditional E-value: 0.7 ARM_TT21_C 134 llGliaekeqsykdAaenYekAWklske 161 lG+ +++++ + +A+e+Yek+ +++ e FUN_000341-T1 88 SLGVAYDSQSDFPKAIECYEKSLNIARE 115 689******************9887665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.015 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskesspavGykLAf 172 ++Ay +G+ +e++ + +A+e+Yek+ +++ e+ + G k A+ FUN_000341-T1 203 GRAYFNIGFAYESQRDFPKAIECYEKSLNIAREAGDRDGEKKAY 246 589999*********************99988876666666555 PP == domain 4 score: 12.6 bits; conditional E-value: 0.0002 ARM_TT21_C 59 lalaealvllkqtqkArnqLkriskleysveeadelekawLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsykdA 148 + l a+ +++ +kA + ++ ++ ++ + d +a+ l + y ++ + +A e +k l+ ++ ++Ay +G+ +e++ + +A FUN_000341-T1 247 FNLEVAYNSQRDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFSKAIEWYEKSLNIAREAgdrdteGRAYFNIGFAYESQRDFPKA 342 5566788888899999999999889999999999999****************************9998733333369****************** PP ARM_TT21_C 149 aenYekAWklskesspa 165 +e+Yek+ +++ e+ + FUN_000341-T1 343 IECYEKSLDIAREAGDR 359 ******99988876655 PP == domain 5 score: 4.1 bits; conditional E-value: 0.081 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklske 161 +kAy lG+ +++++ + +A+e+Yek+ +++ e FUN_000341-T1 363 KKAYFNLGVAYNSQSDFPKAIECYEKSLNIARE 395 69************************9887665 PP == domain 6 score: 8.0 bits; conditional E-value: 0.0053 ARM_TT21_C 57 allalaealvllkqtqkArnqLkriskleysveeadelekawLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsyk 146 a++ l +a+ +++ +kA + ++ ++ ++ + d +a+ l + y ++ + +A e +k l+ ++ ++Ay lG + ++ + FUN_000341-T1 405 AYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAREAgdrdteGRAYFNLGKAYKSQRDFP 500 566777888889999999999999889999999999999999999999999999999*9999999999988733333359999************* PP ARM_TT21_C 147 dAaenYekAWklske 161 +A+e+Yek+ +++ e FUN_000341-T1 501 KAIECYEKSLNIARE 515 *******99877665 PP >> SPO22 Meiosis protein SPO22/ZIP4 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.0 0.0041 2.6 5 66 .. 96 154 .. 95 169 .. 0.69 2 ! 7.8 0.1 0.0043 2.7 35 66 .. 283 314 .. 254 326 .. 0.65 3 ? -3.0 0.0 8.9 5.5e+03 251 273 .. 328 350 .. 326 351 .. 0.87 4 ! 8.2 0.0 0.0034 2.1 5 66 .. 376 434 .. 373 446 .. 0.71 5 ? 5.4 0.1 0.024 15 251 273 .. 448 470 .. 446 471 .. 0.89 6 ? -2.1 0.0 4.7 2.9e+03 251 273 .. 488 510 .. 486 511 .. 0.87 7 ? -2.7 0.0 7 4.4e+03 124 175 .. 1098 1146 .. 1083 1168 .. 0.81 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0041 SPO22 5 qgdldlAehmlskaaednllsldpetaeeLarllYnigksllskkkyeeavkWLqraldile 66 q+d+ A +++k + n+ + + + r ++n gk+ s++++ +a+ W +++l i FUN_000341-T1 96 QSDFPKAIECYEK-S-LNIARE-AGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 154 6677777777777.2.233332.455555677888888888888888888888888888765 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0043 SPO22 35 arllYnigksllskkkyeeavkWLqraldile 66 r ++n gk+ s++++++a+ W +++l i FUN_000341-T1 283 GRAYFNLGKAYKSQRDFSKAIEWYEKSLNIAR 314 56777778887788888888888777777765 PP == domain 3 score: -3.0 bits; conditional E-value: 8.9 SPO22 251 kkgkkaykaknydeAaeWyelal 273 + g + ++++++++A+e ye++l FUN_000341-T1 328 NIGFAYESQRDFPKAIECYEKSL 350 66778899************998 PP == domain 4 score: 8.2 bits; conditional E-value: 0.0034 SPO22 5 qgdldlAehmlskaaednllsldpetaeeLarllYnigksllskkkyeeavkWLqraldile 66 q+d+ A +++k + n+ + + + r ++n gk+ s++++ +a+ W +++l i FUN_000341-T1 376 QSDFPKAIECYEK-S-LNIARE-AGDRDTEGRAYFNLGKAYKSQRDFPKAIEWYEKSLNIAR 434 6777777777777.2.233333.556666678888888888888888888888888888876 PP == domain 5 score: 5.4 bits; conditional E-value: 0.024 SPO22 251 kkgkkaykaknydeAaeWyelal 273 + gk+ +++++++A+eWye++l FUN_000341-T1 448 NLGKAYKSQRDFPKAIEWYEKSL 470 77899999*************98 PP == domain 6 score: -2.1 bits; conditional E-value: 4.7 SPO22 251 kkgkkaykaknydeAaeWyelal 273 + gk+ +++++++A+e ye++l FUN_000341-T1 488 NLGKAYKSQRDFPKAIECYEKSL 510 7789999999**********998 PP == domain 7 score: -2.7 bits; conditional E-value: 7 SPO22 124 llLkleillkeeadeeeiedalmrmirsvdlsetnfklilshikklaekspk 175 l+Lkle ee +++a +mi++ + + +++ +i+ + l+++s++ FUN_000341-T1 1098 LWLKLER--EGILEEELLQHAWGQMIDEHH-TFESLIAIMEKFSLLCSWSSS 1146 7888883..56667777888999***9887.888888899988888887775 PP >> TPR_P4H Prolyl 4-hydroxylase peptide-substrate-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 6 3.8e+03 44 72 .. 45 73 .. 8 115 .. 0.55 2 ! 7.6 0.0 0.0094 5.9 4 73 .. 126 194 .. 123 235 .. 0.84 3 ? 7.4 0.0 0.011 6.9 4 74 .. 286 355 .. 283 370 .. 0.74 4 ? 3.5 0.0 0.17 1.1e+02 4 31 .. 406 433 .. 403 445 .. 0.77 5 ? 4.6 0.0 0.082 51 4 40 .. 446 483 .. 443 526 .. 0.73 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 6 TPR_P4H 44 iLdyLayalyqqgdlkraleLtkrllkld 72 + L a+ q+d +a+e ++ l+++ FUN_000341-T1 45 VYFNLGVAYNSQSDFPKAIECYEKSLNIA 73 44445555555555555555444444333 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0094 TPR_P4H 4 cfelgkvaynekDyyhtvlWleealkrldegeektvekveiLdyLayalyqqgdlkraleLtkrllkldp 73 f+lgk+ ++D+ ++ W e++l+ e + ++++ L a+ q+d +a+e ++ l+++ FUN_000341-T1 126 YFNLGKAYKSQRDFPKAIEWYEKSLNIAREAGD-RDGEKDVYFNLGMAYNSQSDFPKAIECYEKSLNIAR 194 599***9999**************976554444.445678888999999999999999998888777765 PP == domain 3 score: 7.4 bits; conditional E-value: 0.011 TPR_P4H 4 cfelgkvaynekDyyhtvlWleealkr.ldegeektvekveiLdyLayalyqqgdlkraleLtkrllkldpe 74 f+lgk+ ++D+ ++ W e++l+ ++g+ t+ ++ + +a+ q d +a+e ++ l ++ e FUN_000341-T1 286 YFNLGKAYKSQRDFSKAIEWYEKSLNIaREAGDRDTEGRAYF--NIGFAYESQRDFPKAIECYEKSLDIARE 355 599***9999**************875156677777665543..5788888888888888887777766654 PP == domain 4 score: 3.5 bits; conditional E-value: 0.17 TPR_P4H 4 cfelgkvaynekDyyhtvlWleealkrl 31 f+lgk+ ++D+ ++ W e++l+ FUN_000341-T1 406 YFNLGKAYKSQRDFPKAIEWYEKSLNIA 433 599***9999*************97643 PP == domain 5 score: 4.6 bits; conditional E-value: 0.082 TPR_P4H 4 cfelgkvaynekDyyhtvlWleealkr.ldegeektve 40 f+lgk+ ++D+ ++ W e++l+ ++g+ t+ FUN_000341-T1 446 YFNLGKAYKSQRDFPKAIEWYEKSLNIaREAGDRDTEG 483 599***9999*************986414556666654 PP >> Cerato-platanin Cerato-platanin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 9.3 5.8e+03 66 93 .. 12 39 .. 9 48 .. 0.88 2 ? -1.1 0.0 4.5 2.8e+03 64 92 .. 50 78 .. 41 86 .. 0.90 3 ? 2.9 0.0 0.26 1.6e+02 64 103 .. 90 130 .. 83 138 .. 0.88 4 ? 2.6 0.0 0.32 2e+02 65 99 .. 171 205 .. 166 239 .. 0.92 5 ? 3.1 0.0 0.23 1.4e+02 64 104 .. 250 291 .. 242 303 .. 0.86 6 ? -1.5 0.0 6.1 3.8e+03 67 99 .. 293 325 .. 287 330 .. 0.85 7 ? 4.2 0.0 0.1 63 64 103 .. 370 410 .. 363 420 .. 0.88 8 ? -1.0 0.0 4.3 2.7e+03 68 103 .. 414 450 .. 407 459 .. 0.79 9 ? -0.9 0.0 4 2.5e+03 67 103 .. 453 490 .. 443 499 .. 0.80 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 9.3 Cerato-platanin 66 tyngktiyvlaidaagaGfniakkamde 93 y++++ ++ ai+ + +nia++a d+ FUN_000341-T1 12 AYKSQSDFLKAIECYEKSLNIAREAGDR 39 58899999***************99775 PP == domain 2 score: -1.1 bits; conditional E-value: 4.5 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamd 92 ++ yn+++ + ai+ + +nia++a d FUN_000341-T1 50 GVAYNSQSDFPKAIECYEKSLNIAREAGD 78 689**********************9977 PP == domain 3 score: 2.9 bits; conditional E-value: 0.26 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 ++ y++++ + ai+ + +nia++a d+ t+g+a +lG FUN_000341-T1 90 GVAYDSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYfNLG 130 6899*****************************99853566 PP == domain 4 score: 2.6 bits; conditional E-value: 0.32 Cerato-platanin 65 ityngktiyvlaidaagaGfniakkamdeltngqa 99 + yn+++ + ai+ + +nia++a d+ t+g+a FUN_000341-T1 171 MAYNSQSDFPKAIECYEKSLNIAREAGDRDTEGRA 205 789****************************9998 PP == domain 5 score: 3.1 bits; conditional E-value: 0.23 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa.elGr 104 ++ yn++ + ai+ + +nia++a d+ t+g+a +lG+ FUN_000341-T1 250 EVAYNSQRDFPKAIECYEKSLNIAREAGDRDTEGRAYfNLGK 291 6899*999**************************99536665 PP == domain 6 score: -1.5 bits; conditional E-value: 6.1 Cerato-platanin 67 yngktiyvlaidaagaGfniakkamdeltngqa 99 y+++ + ai+ + +nia++a d+ t+g+a FUN_000341-T1 293 YKSQRDFSKAIEWYEKSLNIAREAGDRDTEGRA 325 6666667789999999***********999988 PP == domain 7 score: 4.2 bits; conditional E-value: 0.1 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 ++ yn+++ + ai+ + +nia++a d+ t+g+a +lG FUN_000341-T1 370 GVAYNSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYfNLG 410 689******************************99853566 PP == domain 8 score: -1.0 bits; conditional E-value: 4.3 Cerato-platanin 68 ngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 +++ + ai+ + +nia++a d+ t+g+a +lG FUN_000341-T1 414 KSQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYfNLG 450 5555566789999999*************99853566 PP == domain 9 score: -0.9 bits; conditional E-value: 4 Cerato-platanin 67 yngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 y+++ + ai+ + +nia++a d+ t+g+a +lG FUN_000341-T1 453 YKSQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYfNLG 490 55555666789999999*************99853566 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 1.3 7.9e+02 67 113 .. 17 63 .. 14 76 .. 0.83 2 ? 2.8 0.0 0.26 1.6e+02 64 106 .. 94 136 .. 89 144 .. 0.90 3 ? 2.2 0.0 0.38 2.4e+02 65 113 .. 135 183 .. 134 195 .. 0.87 4 ? 3.6 0.0 0.15 91 65 105 .. 215 255 .. 213 256 .. 0.93 5 ? 4.2 0.1 0.091 56 65 113 .. 255 303 .. 254 316 .. 0.87 6 ? 0.5 0.0 1.3 8.1e+02 65 113 .. 335 383 .. 324 393 .. 0.88 7 ? 0.7 0.0 1.1 7e+02 67 107 .. 377 417 .. 371 431 .. 0.84 8 ? 2.5 0.0 0.32 2e+02 65 108 .. 415 458 .. 414 473 .. 0.86 9 ? 2.4 0.0 0.32 2e+02 65 108 .. 455 498 .. 454 512 .. 0.87 10 ? 1.5 0.0 0.63 3.9e+02 65 108 .. 495 538 .. 494 549 .. 0.88 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1.3 Ulvan_lyase_2nd 67 rkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 ++ + e ye ln+a+ g ++ e+++ +L ay+++ ++ +ai FUN_000341-T1 17 SDFLKAIECYEKSLNIAREAGDRDCEKDVYFNLGVAYNSQSDFPKAI 63 567788899*******************9999999998887766665 PP == domain 2 score: 2.8 bits; conditional E-value: 0.26 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydae 106 Ds+ ++ + e ye ln+a+ g ++ e +a +L +ay+++ FUN_000341-T1 94 DSQSDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQ 136 89999999****************************9999765 PP == domain 3 score: 2.2 bits; conditional E-value: 0.38 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 s+r++ + e ye ln+a+ g ++ e+++ +L +ay+++ ++ +ai FUN_000341-T1 135 SQRDFPKAIEWYEKSLNIAREAGDRDGEKDVYFNLGMAYNSQSDFPKAI 183 689999999******************************9887776666 PP == domain 4 score: 3.6 bits; conditional E-value: 0.15 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqayda 105 s+r++ + e ye ln+a+ g ++ e+ka +L+ ay++ FUN_000341-T1 215 SQRDFPKAIECYEKSLNIAREAGDRDGEKKAYFNLEVAYNS 255 7899999**************************99999975 PP == domain 5 score: 4.2 bits; conditional E-value: 0.091 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 s+r++ + e ye ln+a+ g ++ e +a +L +ay+++ ++++ai FUN_000341-T1 255 SQRDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFSKAI 303 78999999*******************************9887777776 PP == domain 6 score: 0.5 bits; conditional E-value: 1.3 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 s+r++ + e ye l++a+ g ++ +ka +L ay+++ ++ +ai FUN_000341-T1 335 SQRDFPKAIECYEKSLDIAREAGDRDGGKKAYFNLGVAYNSQSDFPKAI 383 7899999************************999999998887666655 PP == domain 7 score: 0.7 bits; conditional E-value: 1.1 Ulvan_lyase_2nd 67 rkndeteelyelalnlakrkgyteleekaealLkqaydaeG 107 ++ + e ye ln+a+ g ++ e +a +L +ay+++ FUN_000341-T1 377 SDFPKAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQR 417 566677899**************************998765 PP == domain 8 score: 2.5 bits; conditional E-value: 0.32 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGg 108 s+r++ + e ye ln+a+ g ++ e +a +L +ay+++ + FUN_000341-T1 415 SQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRD 458 689999999****************************9987655 PP == domain 9 score: 2.4 bits; conditional E-value: 0.32 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGg 108 s+r++ + e ye ln+a+ g ++ e +a +L +ay+++ + FUN_000341-T1 455 SQRDFPKAIEWYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRD 498 689999999****************************9987655 PP == domain 10 score: 1.5 bits; conditional E-value: 0.63 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGg 108 s+r++ + e ye ln+a+ g ++ e+++ L +ay+++ + FUN_000341-T1 495 SQRDFPKAIECYEKSLNIAREAGDRDGEKDVYFSLGNAYNSQSD 538 68999999***********************9999999987755 PP >> ssDBP Phage single-stranded DNA-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 1 6.5e+02 25 48 .. 48 71 .. 34 82 .. 0.82 2 ? 0.5 0.0 1.3 8.2e+02 26 48 .. 89 111 .. 73 122 .. 0.80 3 ? 3.8 0.0 0.12 76 18 48 .. 122 151 .. 113 162 .. 0.80 4 ? 1.6 0.0 0.6 3.8e+02 24 48 .. 167 191 .. 152 201 .. 0.80 5 ! 7.4 0.1 0.0096 6 18 48 .. 202 231 .. 193 241 .. 0.83 6 ? 0.4 0.0 1.4 8.7e+02 27 48 .. 250 271 .. 232 282 .. 0.76 7 ? -0.7 0.0 3.1 2e+03 18 48 .. 282 311 .. 273 320 .. 0.79 8 ! 8.1 0.1 0.0058 3.6 18 50 .. 322 353 .. 313 360 .. 0.83 9 ? 2.9 0.0 0.24 1.5e+02 17 48 .. 360 391 .. 350 401 .. 0.79 10 ? 3.7 0.0 0.13 80 18 48 .. 402 431 .. 394 440 .. 0.79 11 ? 3.7 0.0 0.13 80 18 48 .. 442 471 .. 434 480 .. 0.79 12 ? 1.5 0.0 0.65 4e+02 18 48 .. 482 511 .. 473 521 .. 0.79 13 ? -1.6 0.0 6.2 3.8e+03 24 42 .. 527 545 .. 509 563 .. 0.79 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 1 ssDBP 25 aeafahledapfPqkisyyveskd 48 + + a+ ++ +fP+ i+ y +s + FUN_000341-T1 48 NLGVAYNSQSDFPKAIECYEKSLN 71 56789**************99854 PP == domain 2 score: 0.5 bits; conditional E-value: 1.3 ssDBP 26 eafahledapfPqkisyyveskd 48 + a+ ++ +fP+ i+ y +s + FUN_000341-T1 89 LGVAYDSQSDFPKAIECYEKSLN 111 57799*************99955 PP == domain 3 score: 3.8 bits; conditional E-value: 0.12 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a++++ +fP+ i++y +s + FUN_000341-T1 122 EGRAY-FNLGKAYKSQRDFPKAIEWYEKSLN 151 56777.56677999************99955 PP == domain 4 score: 1.6 bits; conditional E-value: 0.6 ssDBP 24 maeafahledapfPqkisyyveskd 48 ++ + a+ ++ +fP+ i+ y +s + FUN_000341-T1 167 FNLGMAYNSQSDFPKAIECYEKSLN 191 667899**************99955 PP == domain 5 score: 7.4 bits; conditional E-value: 0.0096 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ +fa++++ +fP+ i+ y +s + FUN_000341-T1 202 EGRAY-FNIGFAYESQRDFPKAIECYEKSLN 231 67888.788*****************99854 PP == domain 6 score: 0.4 bits; conditional E-value: 1.4 ssDBP 27 afahledapfPqkisyyveskd 48 a+ ++ +fP+ i+ y +s + FUN_000341-T1 250 EVAYNSQRDFPKAIECYEKSLN 271 46899************99955 PP == domain 7 score: -0.7 bits; conditional E-value: 3.1 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a++++ +f + i++y +s + FUN_000341-T1 282 EGRAY-FNLGKAYKSQRDFSKAIEWYEKSLN 311 56777.5667789999**********99954 PP == domain 8 score: 8.1 bits; conditional E-value: 0.0058 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskdev 50 +G++Y ++ +fa++++ +fP+ i+ y +s d FUN_000341-T1 322 EGRAY-FNIGFAYESQRDFPKAIECYEKSLDIA 353 67888.788*****************9996655 PP == domain 9 score: 2.9 bits; conditional E-value: 0.24 ssDBP 17 akGnpYtmaeafahledapfPqkisyyveskd 48 G+ ++ + a+ ++ +fP+ i+ y +s + FUN_000341-T1 360 DGGKKAYFNLGVAYNSQSDFPKAIECYEKSLN 391 557777789999***************99955 PP == domain 10 score: 3.7 bits; conditional E-value: 0.13 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a++++ +fP+ i++y +s + FUN_000341-T1 402 EGRAY-FNLGKAYKSQRDFPKAIEWYEKSLN 431 56777.56677999************99954 PP == domain 11 score: 3.7 bits; conditional E-value: 0.13 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a++++ +fP+ i++y +s + FUN_000341-T1 442 EGRAY-FNLGKAYKSQRDFPKAIEWYEKSLN 471 56777.56677999************99954 PP == domain 12 score: 1.5 bits; conditional E-value: 0.65 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a++++ +fP+ i+ y +s + FUN_000341-T1 482 EGRAY-FNLGKAYKSQRDFPKAIECYEKSLN 511 56777.56677999************99854 PP == domain 13 score: -1.6 bits; conditional E-value: 6.2 ssDBP 24 maeafahledapfPqkisy 42 ++ + a+ ++ +fP+k s FUN_000341-T1 527 FSLGNAYNSQSDFPKKKSL 545 55577899999***99875 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.0011 0.66 2 43 .. 609 650 .. 608 665 .. 0.87 2 ! 8.2 0.0 0.0038 2.3 45 83 .. 820 858 .. 791 884 .. 0.77 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0011 Ras 2 lvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvev 43 ++l+G++ GK+sl + +F+ + +sT+g+d + ++v FUN_000341-T1 609 IMLIGQERSGKTSLKKSLQGLQFNPNEDSTVGIDADPSYFKV 650 689******************************987666555 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0038 Ras 45 gkevklqiwDTAGqerfralreayyrgaegillvydits 83 + ++ +wD AG + + +++++++ + llvyd+++ FUN_000341-T1 820 EDDIYSVLWDFAGESVYYETHQLFLTSRAIYLLVYDLSR 858 56677789****************************976 PP >> Glyco_transf_4 Glycosyltransferase Family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 5.7e-06 0.0036 2 152 .. 1486 1635 .. 1485 1641 .. 0.79 2 ? -1.2 0.0 4 2.5e+03 51 100 .. 1723 1773 .. 1690 1787 .. 0.57 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 5.7e-06 Glyco_transf_4 2 GGverhvleLaraLar.rGheVtvvtpggpgeleeeevrvvrvpsvplplpkrllrslaflrrlrrllrrerpDivHahspfalglaalaarr 93 GG+++ +e++ +La+ ++eV + p+ ++e +++ + ++ ++l + + + + l+++ +++ D+v h+ + g + +++ FUN_000341-T1 1486 GGLSTMNREISIQLAKdDNVEVCMYLPAFSEEDKKA---ADKCRV--RLLKAKKKPGYDPIDWLASIPSDHQMDVVIGHGIHL-GKQIPHIKE 1572 9***************66788888888888888888...333444..444445555556677889999999*****9999555.688888888 PP Glyco_transf_4 94 .rlgiplvatyHglfe.lglvgallsplkrllrrlerrl..lrradrviavSeavaeelrery 152 + ++ v +H+ e g+++ + p + ++++e+ + +++ad+v+a+ +++a+ + + + FUN_000341-T1 1573 sHPECKWVQVVHTDPEeCGMFKTYADPTAKGEKKYEAEVelCKQADQVVAIGPKLADTYSHSC 1635 99***************666667777777777777777777*************999887755 PP == domain 2 score: -1.2 bits; conditional E-value: 4 Glyco_transf_4 51 pkrllrslaflrrlrrllrre.rpDivHahspfa.lglaalaarrrlgiplv 100 r++++++ + + +l++++ + D+v s + +glaal a+ g p+ FUN_000341-T1 1723 ISRRQLTVRRAKKREELAQQFyEADLVIMPSRTEgFGLAALEALS-AGLPVL 1773 444555555555555555555666666444443312344444443.566665 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.00026 0.16 4 27 .. 609 632 .. 605 644 .. 0.88 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00026 PduV-EutP 4 illiGkvgsGKttLtqalkgeelk 27 i+liG+ sGKt+L+++l+g++++ FUN_000341-T1 609 IMLIGQERSGKTSLKKSLQGLQFN 632 9******************98875 PP >> YARHG YARHG domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.27 1.7e+02 43 62 .. 120 140 .. 118 155 .. 0.80 2 ? 1.1 0.0 0.89 5.5e+02 43 62 .. 200 220 .. 199 235 .. 0.79 3 ? -0.0 0.0 2.1 1.3e+03 45 62 .. 242 260 .. 239 275 .. 0.77 4 ? 3.2 0.1 0.21 1.3e+02 43 62 .. 280 300 .. 278 315 .. 0.78 5 ? 0.9 0.0 1 6.5e+02 43 62 .. 320 340 .. 319 354 .. 0.81 6 ? -0.6 0.0 3 1.9e+03 46 62 .. 363 380 .. 359 394 .. 0.78 7 ? 2.7 0.0 0.29 1.8e+02 43 62 .. 400 420 .. 399 435 .. 0.79 8 ? 2.7 0.0 0.29 1.8e+02 43 62 .. 440 460 .. 439 475 .. 0.79 9 ? 2.8 0.0 0.27 1.7e+02 43 62 .. 480 500 .. 479 515 .. 0.79 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.27 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ ++ yk++++ + FUN_000341-T1 120 DTEGRAYFNLGKAYKSQRDfP 140 6899**************854 PP == domain 2 score: 1.1 bits; conditional E-value: 0.89 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ + y+++++ + FUN_000341-T1 200 DTEGRAYFNIGFAYESQRDfP 220 6799*************9853 PP == domain 3 score: -0.0 bits; conditional E-value: 2.1 YARHG 45 dlkayFssqcwykpess.f 62 + kayF+ + y+++++ + FUN_000341-T1 242 EKKAYFNLEVAYNSQRDfP 260 569*************853 PP == domain 4 score: 3.2 bits; conditional E-value: 0.21 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ ++ yk++++ + FUN_000341-T1 280 DTEGRAYFNLGKAYKSQRDfS 300 6899**************842 PP == domain 5 score: 0.9 bits; conditional E-value: 1 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ + y+++++ + FUN_000341-T1 320 DTEGRAYFNIGFAYESQRDfP 340 6799*************9853 PP == domain 6 score: -0.6 bits; conditional E-value: 3 YARHG 46 lkayFssqcwykpess.f 62 kayF+ + y+++s+ + FUN_000341-T1 363 KKAYFNLGVAYNSQSDfP 380 59************9853 PP == domain 7 score: 2.7 bits; conditional E-value: 0.29 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ ++ yk++++ + FUN_000341-T1 400 DTEGRAYFNLGKAYKSQRDfP 420 6799**************854 PP == domain 8 score: 2.7 bits; conditional E-value: 0.29 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ ++ yk++++ + FUN_000341-T1 440 DTEGRAYFNLGKAYKSQRDfP 460 6799**************854 PP == domain 9 score: 2.8 bits; conditional E-value: 0.27 YARHG 43 tpdlkayFssqcwykpess.f 62 +++++ayF+ ++ yk++++ + FUN_000341-T1 480 DTEGRAYFNLGKAYKSQRDfP 500 6799**************853 PP >> Phage_tail_tube_init Putative phage tail tube initiator protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 8.4 5.2e+03 144 178 .. 26 60 .. 25 84 .. 0.75 2 ? 0.3 0.0 1 6.4e+02 129 180 .. 90 142 .. 79 184 .. 0.67 3 ? -1.2 0.0 3 1.9e+03 144 178 .. 186 220 .. 164 258 .. 0.74 4 ? 0.4 0.0 0.93 5.8e+02 144 181 .. 266 306 .. 251 366 .. 0.64 5 ? -0.4 0.0 1.7 1e+03 144 180 .. 386 422 .. 368 459 .. 0.64 6 ? -0.8 0.0 2.2 1.4e+03 144 180 .. 426 462 .. 410 497 .. 0.66 7 ? 3.0 0.1 0.16 97 144 188 .. 506 550 .. 491 569 .. 0.81 8 ? -2.4 0.0 6.8 4.2e+03 115 138 .. 695 718 .. 687 719 .. 0.90 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 8.4 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeks 178 Ye +l + r+a++ d e+ v +++G + s ++ FUN_000341-T1 26 YEKSLNIAREAGDRDCEKDVYFNLGVAYNSQSDFP 60 88899999*****9999999999998877776654 PP == domain 2 score: 0.3 bits; conditional E-value: 1 Phage_tail_tube_init 129 glkyersvdsp.LlyrYeiklvvlrkasepddedvvdpeiGNrfpsleeksdk 180 g+ y+ ++d p + Ye +l + r+a++ d e + +++G ++s + ++ FUN_000341-T1 90 GVAYDSQSDFPkAIECYEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKA 142 66665555554133458888899999999999988888888888887665533 PP == domain 3 score: -1.2 bits; conditional E-value: 3 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeks 178 Ye +l + r+a++ d e + ++iG + s + FUN_000341-T1 186 YEKSLNIAREAGDRDTEGRAYFNIGFAYESQRDFP 220 9999********************99888877655 PP == domain 4 score: 0.4 bits; conditional E-value: 0.93 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksdk...s 181 Ye +l + r+a++ d e + +++G ++s + s++ + FUN_000341-T1 266 YEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFSKAiewY 306 66666666666666666666666666666666555432221 PP == domain 5 score: -0.4 bits; conditional E-value: 1.7 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksdk 180 Ye +l + r+a++ d e + +++G ++s + ++ FUN_000341-T1 386 YEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKA 422 7778888888888888888888888877776665533 PP == domain 6 score: -0.8 bits; conditional E-value: 2.2 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksdk 180 Ye +l + r+a++ d e + +++G ++s + ++ FUN_000341-T1 426 YEKSLNIAREAGDRDTEGRAYFNLGKAYKSQRDFPKA 462 7778888888888888888888888887777665533 PP == domain 7 score: 3.0 bits; conditional E-value: 0.16 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksdkseknakkd 188 Ye +l + r+a++ d e+ v + +GN + s ++ +k++ n ++ FUN_000341-T1 506 YEKSLNIAREAGDRDGEKDVYFSLGNAYNSQSDFPKKKSLNIARE 550 9999*************************9999886655544444 PP == domain 8 score: -2.4 bits; conditional E-value: 6.8 Phage_tail_tube_init 115 fTddesyvVhLspeglkyersvds 138 +T d+s v h+sp ++ +sv++ FUN_000341-T1 695 KTVDKSKVLHISPTIFTEAQSVNE 718 5889*****************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1860 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 953 (0.0373067); expected 510.9 (0.02) Passed bias filter: 594 (0.0232531); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 41 [number of targets reported over threshold] # CPU time: 0.73u 0.38s 00:00:01.10 Elapsed: 00:00:00.46 # Mc/sec: 16274.58 // Query: FUN_000342-T1 [L=364] Description: FUN_000342 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-92 303.1 9.1 6.4e-18 65.2 0.2 6.8 7 TPR_12 Tetratricopeptide repeat 3.3e-72 236.1 24.9 2.6e-08 33.8 0.1 10.1 10 TPR_1 Tetratricopeptide repeat 1.4e-57 187.6 18.2 8.6e-07 29.1 0.1 9.8 10 TPR_2 Tetratricopeptide repeat 4.5e-57 185.8 1.0 5.2e-07 29.7 0.0 9.3 9 TPR_7 Tetratricopeptide repeat 4.6e-50 164.0 23.9 1.6e-06 28.3 0.1 9.6 9 TPR_8 Tetratricopeptide repeat 3.4e-37 125.8 0.0 7.6e-05 23.1 0.0 9.3 9 TPR_10 Tetratricopeptide repeat 1.5e-25 88.5 0.0 0.025 15.7 0.0 8.7 8 TPR_6 Tetratricopeptide repeat 3.3e-24 86.3 11.1 6e-09 36.3 0.7 3.0 3 SNAP Soluble NSF attachment protein, SNAP 1.3e-22 78.6 5.7 0.81 10.6 0.0 10.7 9 TPR_17 Tetratricopeptide repeat 1.5e-21 77.0 1.9 2.2e-05 25.3 0.1 7.1 6 TPR_16 Tetratricopeptide repeat 1.3e-18 66.8 50.1 0.0066 16.6 3.6 14.9 14 TPR_11 TPR repeat 3.1e-15 55.7 0.0 0.43 11.9 0.0 8.3 8 TPR_14 Tetratricopeptide repeat 5.1e-13 49.5 0.0 2.1e-06 27.7 0.0 3.4 3 TPR_MalT MalT-like TPR region 5.2e-13 49.3 0.0 0.03 14.9 0.0 6.0 7 TPR_9 Tetratricopeptide repeat 1.9e-12 47.9 0.2 5 7.9 0.0 7.9 7 DUF7018 Domain of unknown function (DUF7018) 5.5e-12 45.5 8.0 0.027 13.6 0.2 5.9 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.9e-10 41.2 6.3 0.046 13.9 0.2 6.5 7 RPN7 26S proteasome subunit RPN7 4.6e-10 39.9 0.9 0.62 10.6 0.2 6.1 7 ANAPC5 Anaphase-promoting complex subunit 5 5.9e-10 39.7 7.4 8 6.7 0.1 8.0 8 DUF7380 Domain of unknown function (DUF7380) 9.4e-09 35.7 12.8 12 6.5 0.0 8.3 8 MIT MIT (microtubule interacting and transport) 1.6e-08 34.4 3.3 27 4.9 0.0 8.2 8 SHNi-TPR SHNi-TPR 2.2e-07 31.3 1.4 10 6.2 0.1 6.7 6 ComR_TPR ComR tetratricopeptide 2.4e-07 31.2 0.2 0.68 10.5 0.0 6.1 7 Rapsyn_N Rapsyn N-terminal myristoylation and linker 2.4e-07 31.5 18.2 7.4 7.8 0.1 9.8 8 Sel1 Sel1 repeat 3.7e-07 30.9 0.8 1.4 9.8 0.0 5.2 7 TPR_19 Tetratricopeptide repeat 5.4e-07 30.1 0.0 0.45 10.8 0.0 5.7 4 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR 1.4e-06 28.6 12.9 2.3 8.7 0.1 7.1 7 ssDBP Phage single-stranded DNA-binding protein 2e-06 28.2 3.4 32 4.9 0.0 6.9 7 TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, 2.9e-06 28.1 6.9 14 6.4 0.0 7.2 9 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth A 5.2e-06 27.2 5.7 1.6 9.6 0.1 5.3 7 ANAPC3 Anaphase-promoting complex, cyclosome, subu 6.8e-06 26.4 0.9 26 5.0 0.0 6.2 7 Clathrin Region in Clathrin and VPS 9.8e-06 26.3 0.0 1.2e+02 3.4 0.0 6.8 7 DUF7971 Family of unknown function (DUF7971) 2.2e-05 24.6 4.2 2.5 8.0 0.1 5.3 6 DUF6377 Domain of unknown function (DUF6377) 6.1e-05 23.3 0.0 4.5 7.4 0.0 4.4 5 TPR_COPA_B COPA/B TPR domain 6.5e-05 23.8 0.2 0.83 10.5 0.0 5.0 4 TPR_IF140_C IF140 C-terminal TPR domain 0.00014 22.7 0.0 83 4.1 0.0 6.4 7 Glyoxalase Glyoxalase/Bleomycin resistance protein/Dio 0.00056 20.8 0.2 20 6.2 0.0 5.0 5 Glyco_hydro_36C Glycosyl hydrolase family 36 C-terminal dom 0.00097 19.6 3.9 18 5.7 0.0 6.8 8 CoV_NSP8 Coronavirus replicase NSP8 0.0012 19.5 0.3 4 8.1 0.0 4.1 5 TPR_EMC2 EMC2 TPR-like repeat domain 0.0017 19.2 3.5 32 5.4 0.0 6.1 6 TPR_Slam Surface lipoprotein assembly modifier, N-te 0.0022 18.6 2.3 15 6.3 0.0 5.2 6 WH_Halo_primase Halobacteria primase winged helix domain 0.0028 17.3 9.6 2.7 7.6 0.1 4.9 6 AimR AimR transcriptional regulator-like 0.004 17.9 0.3 54 4.5 0.0 4.9 4 TPR_5 Tetratrico peptide repeat 0.0045 17.7 0.6 33 5.1 0.0 5.0 5 DUF6845 Domain of unknown function (DUF6845) 0.005 16.8 0.0 4.2 7.2 0.0 3.2 3 TPR_NPHP3 Nephrocystin-3 TPR domain ------ inclusion threshold ------ 0.01 15.8 0.5 30 4.4 0.0 4.2 4 TPR_15 Tetratricopeptide repeat 0.01 16.1 0.4 19 5.5 0.0 4.9 7 RE_NgoFVII_C NgoFVII C-terminal B3-like DNA-binding doma 0.013 16.0 1.6 14 6.2 0.1 4.9 7 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain 0.015 16.0 2.6 25 5.7 0.0 5.0 6 NRBF2_MIT MIT domain of nuclear receptor-binding fact 0.015 15.6 10.6 7.6 6.8 0.7 5.7 5 ARM_TT21_C Tetratricopeptide repeat protein 21 C-termi 0.037 14.5 0.5 34 4.9 0.0 4.6 6 DUF627 Protein of unknown function (DUF627) 0.05 13.9 0.0 43 4.5 0.0 3.2 3 BAG6 BCL2-associated athanogene 6 0.062 13.4 0.0 32 4.6 0.0 3.1 3 Foie-gras_1 Foie gras liver health family 1 0.14 12.1 0.3 2.8 7.8 0.0 3.1 3 SPO22 Meiosis protein SPO22/ZIP4 like 0.22 10.4 0.0 15 4.4 0.0 3.4 5 DUF6178 Family of unknown function (DUF6178) 0.3 11.2 0.0 61 3.6 0.0 3.0 3 DUF5385 Family of unknown function (DUF5385) 0.39 11.4 13.3 18 6.0 0.1 5.4 7 PT26-6P_helical PT26-6P, helical domain 0.63 10.8 2.3 30 5.4 0.1 3.8 3 DHR-2_Lobe_A DHR-2, Lobe A 0.92 11.0 27.0 3e+02 3.5 0.1 9.7 9 NSF Aromatic-di-Alanine (AdAR) repeat 8.7 6.8 8.0 28 5.2 0.0 5.2 6 Cdc6_lid Cdc6 AAA+ ATPase-type lid domain Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.7 0.1 6.5e-13 2.8e-10 23 77 .] 3 55 .. 1 55 [. 0.96 2 ! 56.5 0.0 7.6e-18 3.2e-15 8 76 .. 28 94 .. 28 95 .. 0.98 3 ! 54.1 0.0 4.5e-17 1.9e-14 4 76 .. 101 171 .. 98 172 .. 0.95 4 ! 45.1 0.0 2.8e-14 1.2e-11 18 75 .. 155 210 .. 153 212 .. 0.96 5 ! 65.2 0.2 1.5e-20 6.4e-18 4 77 .] 221 292 .. 218 292 .. 0.96 6 ! 59.1 0.0 1.2e-18 5.1e-16 5 75 .. 262 330 .. 261 332 .. 0.96 7 ! 24.9 0.0 5.5e-08 2.4e-05 4 63 .. 301 358 .. 300 358 .. 0.91 Alignments for each domain: == domain 1 score: 40.7 bits; conditional E-value: 6.5e-13 TPR_12 23 lellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +e++ek+l++a+++ +d+ + +a +nLg++y+ l d+ +A++++e++l+ia+k FUN_000342-T1 3 IECYEKSLDIAREE--GDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARK 55 79*********999..9999********************************996 PP == domain 2 score: 56.5 bits; conditional E-value: 7.6e-18 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 nl+ +++ l ++ +A++++ek+l++a+++ +d+ + ++++nLg +y d+ +A+e++e++l+ia+ FUN_000342-T1 28 NLGTAYHSLSDLPKAIDYYEKSLNIARKV--GDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNIAR 94 89***************************..99**********************************98 PP == domain 3 score: 54.1 bits; conditional E-value: 4.5e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ ++ +g + +A+e+++k+l++a ++ +d + a++nLg++y d+ +A+e++e++l+ia FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNIAIEA--GDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIAS 171 6899**************************999..8999*******************************985 PP == domain 4 score: 45.1 bits; conditional E-value: 2.8e-14 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 ++ +A+e++ek+l++a+++ +d+ + ++++nLg +y d+ +A+e++e++l+ia FUN_000342-T1 155 DFPKAIECYEKSLNIASEA--GDRATEGNVYFNLGNAYDSISDFPKAIECYEKSLNIA 210 789**************99..99*********************************98 PP == domain 5 score: 65.2 bits; conditional E-value: 1.5e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++nl+ ++ +g++++A e++ek+l++a+++ d+ + a++nLg ++ +gd+ +A+e++e++l+ia++ FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLNIAREA--SDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 292 5899*****************************..99**********************************986 PP == domain 6 score: 59.1 bits; conditional E-value: 1.2e-18 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ nl++++ +g++ +A+e++ek+l++a+++ +d+ + ta++nLg++y d+ A+e++e++l+ia FUN_000342-T1 262 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREE--GDRAREGTAYFNLGIAYKSHRDFPRAIECYEKSLNIA 330 6779*************************999..9999******************************996 PP == domain 7 score: 24.9 bits; conditional E-value: 5.5e-08 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyee 63 ta+ nl+ ++ ++ A+e++ek+l++a ++ +d+ + ++ nLg+++ d+++ FUN_000342-T1 301 TAYFNLGIAYKSHRDFPRAIECYEKSLNIAWEA--GDRAREGKTYLNLGIALKSHSDFQK 358 67889*************************555..99***************99999885 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.14 61 21 31 .. 3 13 .. 1 15 [. 0.87 2 ! 28.5 0.1 3e-09 1.3e-06 2 31 .. 24 53 .. 23 55 .. 0.92 3 ! 30.6 0.1 6.5e-10 2.8e-07 3 31 .. 65 93 .. 63 95 .. 0.92 4 ! 26.8 0.2 1e-08 4.3e-06 2 30 .. 101 129 .. 100 130 .. 0.94 5 ! 30.5 0.1 7.1e-10 3e-07 2 30 .. 141 169 .. 140 172 .. 0.93 6 ! 29.9 0.0 1.1e-09 4.5e-07 3 30 .. 182 209 .. 180 210 .. 0.93 7 ! 32.1 0.2 2.2e-10 9.3e-08 2 31 .. 221 250 .. 220 252 .. 0.93 8 ! 33.8 0.1 6.1e-11 2.6e-08 2 31 .. 261 290 .. 260 292 .. 0.93 9 ! 26.7 0.0 1.1e-08 4.8e-06 3 30 .. 302 329 .. 301 330 .. 0.94 10 ? 3.3 0.0 0.26 1.1e+02 2 19 .. 341 358 .. 340 358 .. 0.89 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.14 TPR_1 21 leyyekALeln 31 +e+yek L + FUN_000342-T1 3 IECYEKSLDIA 13 8*******986 PP == domain 2 score: 28.5 bits; conditional E-value: 3e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay++l ++ +A++yyek L + FUN_000342-T1 24 RACFNLGTAYHSLSDLPKAIDYYEKSLNIA 53 699***********************9875 PP == domain 3 score: 30.6 bits; conditional E-value: 6.5e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 +++nlGnay + ++ +A+e+yek L + FUN_000342-T1 65 IYFNLGNAYDSISDFPKAIECYEKSLNIA 93 7************************9876 PP == domain 4 score: 26.8 bits; conditional E-value: 1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay ++g + +A+e+y+k L + FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNI 129 79***********************9965 PP == domain 5 score: 30.5 bits; conditional E-value: 7.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a++nlG ay + ++ +A+e+yek L + FUN_000342-T1 141 DAYFNLGIAYKSHSDFPKAIECYEKSLNI 169 79************************977 PP == domain 6 score: 29.9 bits; conditional E-value: 1.1e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 +++nlGnay + ++ +A+e+yek L + FUN_000342-T1 182 VYFNLGNAYDSISDFPKAIECYEKSLNI 209 8***********************9965 PP == domain 7 score: 32.1 bits; conditional E-value: 2.2e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay ++g++ +A e+yek L + FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLNIA 250 79************************9775 PP == domain 8 score: 33.8 bits; conditional E-value: 6.1e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG a+ ++g++ +A+eyyek L + FUN_000342-T1 261 DAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 290 79************************9775 PP == domain 9 score: 26.7 bits; conditional E-value: 1.1e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a++nlG ay + ++ A+e+yek L + FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIECYEKSLNI 329 9***********************9965 PP == domain 10 score: 3.3 bits; conditional E-value: 0.26 TPR_1 2 kalynlGnayfklgkyde 19 k++ nlG a+ + ++++ FUN_000342-T1 341 KTYLNLGIALKSHSDFQK 358 68********99999886 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 1.6 6.8e+02 21 31 .. 3 13 .. 3 16 .. 0.85 2 ! 21.7 0.0 4.9e-07 0.00021 2 31 .. 24 53 .. 23 55 .. 0.93 3 ! 23.0 0.0 1.8e-07 7.8e-05 3 33 .. 65 95 .. 63 96 .. 0.93 4 ! 19.0 0.1 3.6e-06 0.0015 2 31 .. 101 130 .. 100 133 .. 0.93 5 ! 24.5 0.0 6e-08 2.5e-05 2 31 .. 141 170 .. 140 173 .. 0.93 6 ! 22.6 0.0 2.5e-07 0.00011 3 31 .. 182 210 .. 180 213 .. 0.93 7 ! 26.1 0.1 1.8e-08 7.7e-06 2 32 .. 221 251 .. 220 253 .. 0.93 8 ! 29.1 0.1 2e-09 8.6e-07 2 31 .. 261 290 .. 260 293 .. 0.93 9 ! 24.0 0.0 8.9e-08 3.8e-05 3 30 .. 302 329 .. 300 330 .. 0.94 10 ? -0.5 0.0 6.1 2.6e+03 3 18 .. 342 357 .. 338 359 .. 0.61 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 1.6 TPR_2 21 leayekAleld 31 +e+yek+l ++ FUN_000342-T1 3 IECYEKSLDIA 13 79******987 PP == domain 2 score: 21.7 bits; conditional E-value: 4.9e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG ay l d+ +A+++yek+l ++ FUN_000342-T1 24 RACFNLGTAYHSLSDLPKAIDYYEKSLNIA 53 69*************************987 PP == domain 3 score: 23.0 bits; conditional E-value: 1.8e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAleldPn 33 +++nlG+ay d+ +A+e+yek+l ++ + FUN_000342-T1 65 IYFNLGNAYDSISDFPKAIECYEKSLNIARD 95 79************************99865 PP == domain 4 score: 19.0 bits; conditional E-value: 3.6e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlG ay +g + +A+e+y+k+l ++ FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNIA 130 69************************9875 PP == domain 5 score: 24.5 bits; conditional E-value: 6e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG ay d+ +A+e+yek+l ++ FUN_000342-T1 141 DAYFNLGIAYKSHSDFPKAIECYEKSLNIA 170 69*************************987 PP == domain 6 score: 22.6 bits; conditional E-value: 2.5e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 +++nlG+ay d+ +A+e+yek+l ++ FUN_000342-T1 182 VYFNLGNAYDSISDFPKAIECYEKSLNIA 210 89************************986 PP == domain 7 score: 26.1 bits; conditional E-value: 1.8e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ nlG ay +gd+ +A e+yek+l ++ FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLNIAR 251 69*************************9975 PP == domain 8 score: 29.1 bits; conditional E-value: 2e-09 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG a+ +gd+ +A+e+yek+l ++ FUN_000342-T1 261 DAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 290 69*************************987 PP == domain 9 score: 24.0 bits; conditional E-value: 8.9e-08 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a++nlG ay d+ +A+e+yek+l + FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIECYEKSLNI 329 9************************987 PP == domain 10 score: -0.5 bits; conditional E-value: 6.1 TPR_2 3 alynlGlayyklgdye 18 + nlG a+ d++ FUN_000342-T1 342 TYLNLGIALKSHSDFQ 357 4667777766665555 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 0.14 60 19 36 .] 3 20 .. 3 20 .. 0.92 2 ! 24.6 0.0 5.6e-08 2.4e-05 1 36 [] 25 60 .. 25 60 .. 0.97 3 ! 22.7 0.0 2.2e-07 9.4e-05 3 35 .. 67 99 .. 65 100 .. 0.94 4 ! 16.1 0.0 2.9e-05 0.012 1 35 [. 102 136 .. 102 137 .. 0.92 5 ! 16.9 0.0 1.7e-05 0.0071 1 36 [] 142 177 .. 142 177 .. 0.95 6 ! 19.9 0.0 1.8e-06 0.00076 2 35 .. 183 216 .. 182 217 .. 0.92 7 ! 23.9 0.1 9.4e-08 4e-05 1 36 [] 222 257 .. 222 257 .. 0.95 8 ! 29.7 0.0 1.2e-09 5.2e-07 1 36 [] 262 297 .. 262 297 .. 0.96 9 ! 15.9 0.0 3.3e-05 0.014 1 34 [. 302 335 .. 302 337 .. 0.87 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.14 TPR_7 19 irlyerlLalakdpedre 36 i++ye+ L++a++++dr+ FUN_000342-T1 3 IECYEKSLDIAREEGDRA 20 789*************96 PP == domain 2 score: 24.6 bits; conditional E-value: 5.6e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L+ +y++l d +Ai++ye+ L +a++ +dr+ FUN_000342-T1 25 ACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRA 60 8********************************995 PP == domain 3 score: 22.7 bits; conditional E-value: 2.2e-07 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +L+++y + d+ +Ai++ye+ L +a+d +d+ FUN_000342-T1 67 FNLGNAYDSISDFPKAIECYEKSLNIARDAGDQ 99 79***************************9985 PP == domain 4 score: 16.1 bits; conditional E-value: 2.9e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y ++G + +Ai++y++ L +a + +d+ FUN_000342-T1 102 AYLNLGIAYKSQGGFPKAIECYKKSLNIAIEAGDQ 136 789***********************999888775 PP == domain 5 score: 16.9 bits; conditional E-value: 1.7e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L+ +y + d+ +Ai++ye+ L +a + +dr+ FUN_000342-T1 142 AYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRA 177 789***************************999985 PP == domain 6 score: 19.9 bits; conditional E-value: 1.8e-06 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y + d+ +Ai++ye+ L +a++ +++ FUN_000342-T1 183 YFNLGNAYDSISDFPKAIECYEKSLNIAMEAGHQ 216 579************************9998875 PP == domain 7 score: 23.9 bits; conditional E-value: 9.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +y ++Gd+ +A ++ye+ L +a++ +dr+ FUN_000342-T1 222 AYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRA 257 789****************************99985 PP == domain 8 score: 29.7 bits; conditional E-value: 1.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L++++ ++Gd+ +Ai++ye+ L +a++++dr+ FUN_000342-T1 262 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRA 297 789*******************************96 PP == domain 9 score: 15.9 bits; conditional E-value: 3.3e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+ +L+ +y + +d+ +Ai++ye+ L +a + +d FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIECYEKSLNIAWEAGD 335 789*********************9988755555 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.54 2.3e+02 21 33 .. 3 15 .. 3 16 .. 0.89 2 ! 22.7 0.0 2.3e-07 9.7e-05 2 33 .. 24 55 .. 23 56 .. 0.95 3 ! 22.3 0.0 3.1e-07 0.00013 3 33 .. 65 95 .. 63 95 .. 0.94 4 ! 16.3 0.1 2.6e-05 0.011 2 30 .. 101 129 .. 100 130 .. 0.95 5 ! 17.4 0.1 1.2e-05 0.0049 2 31 .. 141 170 .. 140 172 .. 0.94 6 ! 20.3 0.0 1.4e-06 0.0006 3 30 .. 182 209 .. 180 210 .. 0.94 7 ! 27.5 0.2 6.9e-09 3e-06 2 32 .. 221 251 .. 220 252 .. 0.95 8 ! 28.3 0.1 3.7e-09 1.6e-06 2 33 .. 261 292 .. 260 293 .. 0.94 9 ! 16.0 0.0 3.4e-05 0.014 3 30 .. 302 329 .. 300 330 .. 0.94 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.54 TPR_8 21 keyyekaleldpd 33 +e+yek+l+++++ FUN_000342-T1 3 IECYEKSLDIARE 15 79*******9975 PP == domain 2 score: 22.7 bits; conditional E-value: 2.3e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldpd 33 +a++nlG +y++l d+ +A+ yyek+l ++++ FUN_000342-T1 24 RACFNLGTAYHSLSDLPKAIDYYEKSLNIARK 55 89**************************9975 PP == domain 3 score: 22.3 bits; conditional E-value: 3.1e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldpd 33 +y+nlG++y + d+ +A+e+yek+l +++d FUN_000342-T1 65 IYFNLGNAYDSISDFPKAIECYEKSLNIARD 95 8**************************9975 PP == domain 4 score: 16.3 bits; conditional E-value: 2.6e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay+nlG +y+++g + +A+e+y+k+l + FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNI 129 69************************988 PP == domain 5 score: 17.4 bits; conditional E-value: 1.2e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay+nlG +y++ d+ +A+e+yek+l ++ FUN_000342-T1 141 DAYFNLGIAYKSHSDFPKAIECYEKSLNIA 170 69*************************997 PP == domain 6 score: 20.3 bits; conditional E-value: 1.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 +y+nlG++y + d+ +A+e+yek+l + FUN_000342-T1 182 VYFNLGNAYDSISDFPKAIECYEKSLNI 209 8************************988 PP == domain 7 score: 27.5 bits; conditional E-value: 6.9e-09 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y+++gd+ +A e+yek+l +++ FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLNIAR 251 69*************************9987 PP == domain 8 score: 28.3 bits; conditional E-value: 3.7e-09 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldpd 33 +ay+nlG++++++gd+ +A+eyyek+l ++++ FUN_000342-T1 261 DAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 292 69**************************9975 PP == domain 9 score: 16.0 bits; conditional E-value: 3.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay+nlG +y++ d+ A+e+yek+l + FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIECYEKSLNI 329 9************************988 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.0 0.00013 0.054 7 35 .. 28 56 .. 26 56 .. 0.98 2 ! 10.9 0.0 0.0012 0.5 9 37 .. 63 91 .. 63 95 .. 0.83 3 ! 15.5 0.0 4.4e-05 0.019 3 34 .. 101 132 .. 100 133 .. 0.92 4 ? 7.5 0.0 0.014 6.1 7 32 .. 145 170 .. 141 173 .. 0.90 5 ! 11.3 0.0 0.00087 0.37 9 37 .. 180 208 .. 180 217 .. 0.87 6 ! 23.1 0.0 1.8e-07 7.6e-05 3 35 .. 221 253 .. 220 256 .. 0.94 7 ! 18.9 0.0 3.7e-06 0.0016 7 34 .. 265 292 .. 261 293 .. 0.94 8 ! 10.6 0.0 0.0015 0.63 7 31 .. 305 329 .. 301 332 .. 0.91 9 ? -0.6 0.0 5 2.1e+03 4 14 .. 342 352 .. 341 357 .. 0.79 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.00013 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++a+ ++ ++ A +++e++l i+++v FUN_000342-T1 28 NLGTAYHSLSDLPKAIDYYEKSLNIARKV 56 9*************************997 PP == domain 2 score: 10.9 bits; conditional E-value: 0.0012 TPR_10 9 analraqgryeeAeelleealairervlG 37 +n+++++g+ ++ ++ +a++++e+ l+ FUN_000342-T1 63 GNIYFNLGNAYDSISDFPKAIECYEKSLN 91 68899999999999999999999998876 PP == domain 3 score: 15.5 bits; conditional E-value: 4.4e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 +++ nL+ a+ +qg + A e ++++l i+ + FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNIAIE 132 5899***********************99765 PP == domain 4 score: 7.5 bits; conditional E-value: 0.014 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+ a+ + ++ A e +e++l i+ FUN_000342-T1 145 NLGIAYKSHSDFPKAIECYEKSLNIA 170 9*********************9886 PP == domain 5 score: 11.3 bits; conditional E-value: 0.00087 TPR_10 9 analraqgryeeAeelleealairervlG 37 +n+++++g+ ++ ++ +a++++e+ l+ FUN_000342-T1 180 GNVYFNLGNAYDSISDFPKAIECYEKSLN 208 799**********************9987 PP == domain 6 score: 23.1 bits; conditional E-value: 1.8e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL+ a+ +qg+++ A e +e++l i++++ FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLNIAREA 253 5899**************************997 PP == domain 7 score: 18.9 bits; conditional E-value: 3.7e-06 TPR_10 7 nLanalraqgryeeAeelleealairer 34 nL+ a+ +qg++ A e++e++l i+++ FUN_000342-T1 265 NLGSAHKSQGDFPKAIEYYEKSLNIARE 292 9************************987 PP == domain 8 score: 10.6 bits; conditional E-value: 0.0015 TPR_10 7 nLanalraqgryeeAeelleealai 31 nL+ a+ + +++ +A e +e++l i FUN_000342-T1 305 NLGIAYKSHRDFPRAIECYEKSLNI 329 9*********************987 PP == domain 9 score: -0.6 bits; conditional E-value: 5 TPR_10 4 slnnLanalra 14 ++ nL+ al + FUN_000342-T1 342 TYLNLGIALKS 352 799*****976 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.1 44 4 25 .. 27 48 .. 24 52 .. 0.91 2 ? 5.2 0.0 0.13 57 3 25 .. 66 88 .. 65 93 .. 0.91 3 ! 10.4 0.0 0.003 1.3 1 25 [. 101 125 .. 101 128 .. 0.94 4 ! 9.9 0.0 0.004 1.7 1 25 [. 141 165 .. 141 169 .. 0.92 5 ? 6.0 0.0 0.071 30 2 25 .. 182 205 .. 181 209 .. 0.91 6 ! 14.5 0.0 0.00014 0.059 1 25 [. 221 245 .. 221 249 .. 0.94 7 ! 15.7 0.0 5.8e-05 0.025 1 25 [. 261 285 .. 261 289 .. 0.94 8 ! 9.0 0.0 0.0082 3.5 2 25 .. 302 325 .. 301 329 .. 0.92 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.1 TPR_6 4 lklalsylelgdkdeAkaalqr 25 ++l+ +y l d +A++++++ FUN_000342-T1 27 FNLGTAYHSLSDLPKAIDYYEK 48 89*******99*********98 PP == domain 2 score: 5.2 bits; conditional E-value: 0.13 TPR_6 3 llklalsylelgdkdeAkaalqr 25 +++l+ +y d+ +A++ +++ FUN_000342-T1 66 YFNLGNAYDSISDFPKAIECYEK 88 699*******88*********98 PP == domain 3 score: 10.4 bits; conditional E-value: 0.003 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +y+ +g + +A++ +++ FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKK 125 8**********************97 PP == domain 4 score: 9.9 bits; conditional E-value: 0.004 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+++l+ +y+ d+ +A++ +++ FUN_000342-T1 141 DAYFNLGIAYKSHSDFPKAIECYEK 165 8***********77*********98 PP == domain 5 score: 6.0 bits; conditional E-value: 0.071 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 ++++l+ +y d+ +A++ +++ FUN_000342-T1 182 VYFNLGNAYDSISDFPKAIECYEK 205 589********88*********98 PP == domain 6 score: 14.5 bits; conditional E-value: 0.00014 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +y+ +gd+++A + +++ FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEK 245 8********************9997 PP == domain 7 score: 15.7 bits; conditional E-value: 5.8e-05 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+++l+ +++ +gd+ +A++++++ FUN_000342-T1 261 DAYFNLGSAHKSQGDFPKAIEYYEK 285 8**********************98 PP == domain 8 score: 9.0 bits; conditional E-value: 0.0082 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++l+ +y+ d+ +A++ +++ FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIECYEK 325 99*********88*********98 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 5.7e-07 0.00024 94 180 .. 3 88 .. 1 96 [. 0.95 2 ! 36.3 0.7 1.4e-11 6e-09 35 150 .. 100 215 .. 93 226 .. 0.85 3 ! 34.2 2.5 5.8e-11 2.5e-08 36 145 .. 221 330 .. 212 358 .. 0.89 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 5.7e-07 SNAP 94 vealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 +e++ek+ +i e+g r ++ ++++ y + +dl kAi++Ye++ ++ ++ + a+ +++ ++ + + + +++kAie yek FUN_000342-T1 3 IECYEKSLDIAREEGDRARQGRACFNLGTAYHSL-SDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEK 88 89******************************87.**************************************************97 PP == domain 2 score: 36.3 bits; conditional E-value: 1.4e-11 SNAP 35 adlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelq 129 d y + + ayk + + +A e++ k ++ +++++ ++ay++ +yk+ d +A+e++ek+ +i e+g + ++ ++++++ y++ + FUN_000342-T1 100 GDAYLNLGIAYKSQGGFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHsDFPKAIECYEKSLNIASEAGDRATEGNVYFNLGNAYDSI-S 194 5778888899999999999999999999999999999999999999999999875778999999999999999999999999999999999987.9 PP SNAP 130 dlekAieaYeqAadlyeqeea 150 d+ kAie+Ye++ ++ + + FUN_000342-T1 195 DFPKAIECYEKSLNIAMEAGH 215 999999999998776555555 PP == domain 3 score: 34.2 bits; conditional E-value: 5.8e-11 SNAP 36 dlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqd 130 d y + + ayk + ++++A+e+++k ++ ++++++ ++ay++ + k++ d +A+e +ek+ +i e+g r ++ +++++ y++ d FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRAREGDAYFNLGSAHKSQgDFPKAIEYYEKSLNIAREEGDRAREGTAYFNLGIAYKSH-RD 315 77888899****************************************999987999***********************************9.** PP SNAP 131 lekAieaYeqAadly 145 + +Aie+Ye++ ++ FUN_000342-T1 316 FPRAIECYEKSLNIA 330 *********987764 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.22 92 17 33 .. 27 43 .. 24 44 .. 0.93 2 ! 8.5 0.0 0.0092 3.9 14 34 .] 64 84 .. 60 84 .. 0.89 3 ! 10.6 0.0 0.0019 0.81 11 34 .] 98 121 .. 85 121 .. 0.77 4 ! 9.8 0.0 0.0036 1.5 14 34 .] 141 161 .. 136 161 .. 0.91 5 ? 8.1 0.0 0.012 5 14 34 .] 181 201 .. 177 201 .. 0.89 6 ! 9.6 0.1 0.0041 1.7 14 32 .. 221 239 .. 217 239 .. 0.92 7 ! 9.6 0.0 0.0041 1.7 14 34 .] 261 281 .. 258 281 .. 0.93 8 ? 7.1 0.0 0.026 11 15 34 .] 302 321 .. 299 321 .. 0.92 9 ? 0.7 0.0 2.8 1.2e+03 15 29 .. 342 356 .. 339 358 .. 0.78 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.22 TPR_17 17 ynLArlllnnGqleeAl 33 +nL+++++ + +l +A+ FUN_000342-T1 27 FNLGTAYHSLSDLPKAI 43 8*************997 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0092 TPR_17 14 dayynLArlllnnGqleeAlq 34 ++y+nL++++ ++ +A++ FUN_000342-T1 64 NIYFNLGNAYDSISDFPKAIE 84 79*************999985 PP == domain 3 score: 10.6 bits; conditional E-value: 0.0019 TPR_17 11 nnadayynLArlllnnGqleeAlq 34 + day nL+++++ +G + +A++ FUN_000342-T1 98 DQGDAYLNLGIAYKSQGGFPKAIE 121 5689**************999985 PP == domain 4 score: 9.8 bits; conditional E-value: 0.0036 TPR_17 14 dayynLArlllnnGqleeAlq 34 day+nL+++++ ++ +A++ FUN_000342-T1 141 DAYFNLGIAYKSHSDFPKAIE 161 8***************99985 PP == domain 5 score: 8.1 bits; conditional E-value: 0.012 TPR_17 14 dayynLArlllnnGqleeAlq 34 ++y+nL++++ ++ +A++ FUN_000342-T1 181 NVYFNLGNAYDSISDFPKAIE 201 79*************999985 PP == domain 6 score: 9.6 bits; conditional E-value: 0.0041 TPR_17 14 dayynLArlllnnGqleeA 32 day nL+++++ +G++ +A FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKA 239 8**************9987 PP == domain 7 score: 9.6 bits; conditional E-value: 0.0041 TPR_17 14 dayynLArlllnnGqleeAlq 34 day+nL+ +++ +G++ +A++ FUN_000342-T1 261 DAYFNLGSAHKSQGDFPKAIE 281 8*****************985 PP == domain 8 score: 7.1 bits; conditional E-value: 0.026 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay+nL+++++ ++ +A++ FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIE 321 8************9999985 PP == domain 9 score: 0.7 bits; conditional E-value: 2.8 TPR_17 15 ayynLArlllnnGql 29 y nL+++l+ ++ FUN_000342-T1 342 TYLNLGIALKSHSDF 356 799***999877765 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.1 0.00061 0.26 20 58 .. 10 50 .. 7 60 .. 0.83 2 ! 11.8 0.0 0.00085 0.36 2 58 .. 68 127 .. 67 135 .. 0.85 3 ! 13.2 0.0 0.00032 0.14 1 58 [. 104 167 .. 104 175 .. 0.83 4 ! 11.5 0.0 0.0011 0.45 2 54 .. 185 243 .. 184 253 .. 0.84 5 ! 25.3 0.1 5.1e-08 2.2e-05 1 58 [. 224 287 .. 224 296 .. 0.86 6 ? 7.4 0.0 0.02 8.6 28 58 .. 297 327 .. 285 335 .. 0.70 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00061 TPR_16 20 leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a++ + + +A ++lG a++ + +l++A+++y++ l FUN_000342-T1 10 LDIAREEGdrARQGRACFNLGTAYHSLSDLPKAIDYYEKSL 50 56666666777889999********************9876 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00085 TPR_16 2 alaraalaagdyddAaaaleaalrrn...PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ d++ A++++e l + +A+l+lG a+ qg +++A++ y++ l FUN_000342-T1 68 NLGNAYDSISDFPKAIECYEKSLNIArdaGDQGDAYLNLGIAYKSQGGFPKAIECYKKSL 127 689999999**********887633334899**********************9888765 PP == domain 3 score: 13.2 bits; conditional E-value: 0.00032 TPR_16 1 lalaraalaagdyddAaaalea....alrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l l+ a+ +g ++ A+++++ a++++ + +A+++lG a+ ++++A++ y++ l FUN_000342-T1 104 LNLGIAYKSQGGFPKAIECYKKslniAIEAGdqAREGDAYFNLGIAYKSHSDFPKAIECYEKSL 167 578999999*******999876222266666**99**********************9998876 PP == domain 4 score: 11.5 bits; conditional E-value: 0.0011 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaay 54 l++a+ d++ A++++e l + +A+l+lG a+ qg++++A + y FUN_000342-T1 185 NLGNAYDSISDFPKAIECYEKSLNIAmeaghqAREGDAYLNLGIAYKSQGDFTKASECY 243 6899999999999999999998866666889999*******************996555 PP == domain 5 score: 25.3 bits; conditional E-value: 5.1e-08 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l l+ a+ +gd+ A +++e l + +A+++lG a+ qg++++A+++y++ l FUN_000342-T1 224 LNLGIAYKSQGDFTKASECYEKSLNIAreasdrAREGDAYFNLGSAHKSQGDFPKAIEYYEKSL 287 67999**************9876633335779*99*************************9976 PP == domain 6 score: 7.4 bits; conditional E-value: 0.02 TPR_16 28 PeaaaAllglGlallrqgrlaeAaaayraal 58 + +A+++lG a+ +++++A++ y++ l FUN_000342-T1 297 AREGTAYFNLGIAYKSHRDFPRAIECYEKSL 327 5667778888888888888888877776655 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.017 7.2 1 23 [. 30 52 .. 30 55 .. 0.92 2 ? 5.7 0.3 0.038 16 29 38 .. 64 73 .. 63 77 .. 0.93 3 ! 16.6 3.6 1.6e-05 0.0066 1 42 [] 70 114 .. 70 114 .. 0.89 4 ! 12.2 0.1 0.00038 0.16 3 23 .. 109 129 .. 109 130 .. 0.93 5 ? 5.9 0.3 0.035 15 29 39 .. 141 151 .. 140 154 .. 0.90 6 ? 6.7 0.1 0.02 8.4 9 23 .. 155 169 .. 150 173 .. 0.84 7 ? 4.6 0.2 0.086 37 29 38 .. 181 190 .. 180 194 .. 0.91 8 ! 8.9 0.1 0.0039 1.7 1 23 [. 187 209 .. 187 210 .. 0.92 9 ! 8.0 0.4 0.0077 3.3 29 42 .] 221 234 .. 220 234 .. 0.95 10 ! 12.6 0.1 0.00027 0.12 3 23 .. 229 249 .. 227 253 .. 0.91 11 ! 10.3 0.4 0.0015 0.63 1 23 [. 267 289 .. 260 292 .. 0.87 12 ? 4.9 0.1 0.072 31 29 39 .. 301 311 .. 301 313 .. 0.88 13 ? 3.6 0.0 0.18 76 10 23 .. 316 329 .. 315 330 .. 0.86 14 ? -1.0 0.0 5.1 2.2e+03 31 39 .. 343 351 .. 341 353 .. 0.83 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.017 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay+++ ++++Ai Y+k l++ FUN_000342-T1 30 GTAYHSLSDLPKAIDYYEKSLNI 52 779****************9987 PP == domain 2 score: 5.7 bits; conditional E-value: 0.038 TPR_11 29 eayynLGlay 38 ++y+nLG+ay FUN_000342-T1 64 NIYFNLGNAY 73 69*******9 PP == domain 3 score: 16.6 bits; conditional E-value: 1.6e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPd...naeayynLGlayykqG 42 G+ay + ++++Aie+Y+k l++ d + +ay+nLG ay qG FUN_000342-T1 70 GNAYDSISDFPKAIECYEKSLNIARDagdQGDAYLNLGIAYKSQG 114 89999999***************997222578**********998 PP == domain 4 score: 12.2 bits; conditional E-value: 0.00038 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +qG +++Aie+Ykk l++ FUN_000342-T1 109 AYKSQGGFPKAIECYKKSLNI 129 799**************9987 PP == domain 5 score: 5.9 bits; conditional E-value: 0.035 TPR_11 29 eayynLGlayy 39 +ay+nLG ay FUN_000342-T1 141 DAYFNLGIAYK 151 79********7 PP == domain 6 score: 6.7 bits; conditional E-value: 0.02 TPR_11 9 kyeeAieaYkkAlkl 23 ++++Aie+Y+k l++ FUN_000342-T1 155 DFPKAIECYEKSLNI 169 789********9998 PP == domain 7 score: 4.6 bits; conditional E-value: 0.086 TPR_11 29 eayynLGlay 38 ++y+nLG+ay FUN_000342-T1 181 NVYFNLGNAY 190 68*******9 PP == domain 8 score: 8.9 bits; conditional E-value: 0.0039 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G+ay + ++++Aie+Y+k l++ FUN_000342-T1 187 GNAYDSISDFPKAIECYEKSLNI 209 89999999***********9987 PP == domain 9 score: 8.0 bits; conditional E-value: 0.0077 TPR_11 29 eayynLGlayykqG 42 +ay+nLG ay qG FUN_000342-T1 221 DAYLNLGIAYKSQG 234 79*********998 PP == domain 10 score: 12.6 bits; conditional E-value: 0.00027 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +qG++++A e+Y+k l++ FUN_000342-T1 229 AYKSQGDFTKASECYEKSLNI 249 89***************9987 PP == domain 11 score: 10.3 bits; conditional E-value: 0.0015 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G a +qG++++Aie Y+k l++ FUN_000342-T1 267 GSAHKSQGDFPKAIEYYEKSLNI 289 67888999999999999998887 PP == domain 12 score: 4.9 bits; conditional E-value: 0.072 TPR_11 29 eayynLGlayy 39 +ay+nLG ay FUN_000342-T1 301 TAYFNLGIAYK 311 59********6 PP == domain 13 score: 3.6 bits; conditional E-value: 0.18 TPR_11 10 yeeAieaYkkAlkl 23 ++ Aie+Y+k l++ FUN_000342-T1 316 FPRAIECYEKSLNI 329 678*******9987 PP == domain 14 score: -1.0 bits; conditional E-value: 5.1 TPR_11 31 yynLGlayy 39 y+nLG a+ FUN_000342-T1 343 YLNLGIALK 351 99***9975 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 1.2 5.2e+02 7 28 .. 29 50 .. 24 58 .. 0.86 2 ? 3.1 0.0 0.71 3e+02 3 29 .. 65 91 .. 63 98 .. 0.84 3 ? 4.6 0.0 0.24 1e+02 2 28 .. 101 127 .. 100 134 .. 0.91 4 ? 3.3 0.0 0.63 2.7e+02 3 28 .. 142 167 .. 140 175 .. 0.87 5 ? 2.5 0.0 1.1 4.8e+02 4 28 .. 183 207 .. 181 214 .. 0.85 6 ! 10.2 0.0 0.0036 1.5 2 29 .. 221 248 .. 220 259 .. 0.87 7 ! 11.9 0.0 0.001 0.43 2 29 .. 261 288 .. 260 299 .. 0.87 8 ? 5.3 0.0 0.14 59 3 32 .. 302 331 .. 301 340 .. 0.84 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 1.2 TPR_14 7 larallalGdpdeAlelleral 28 l+ a+ l d+ +A++++e+ l FUN_000342-T1 29 LGTAYHSLSDLPKAIDYYEKSL 50 788999999**********976 PP == domain 2 score: 3.1 bits; conditional E-value: 0.71 TPR_14 3 awlalarallalGdpdeAlellerala 29 ++ l++a+ d+ +A+e++e+ l FUN_000342-T1 65 IYFNLGNAYDSISDFPKAIECYEKSLN 91 5778999999999**********9876 PP == domain 3 score: 4.6 bits; conditional E-value: 0.24 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+l l+ a+ +G + +A+e++++ l FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSL 127 68999******************9866 PP == domain 4 score: 3.3 bits; conditional E-value: 0.63 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+ l+ a+ d+ +A+e++e+ l FUN_000342-T1 142 AYFNLGIAYKSHSDFPKAIECYEKSL 167 78889999***************976 PP == domain 5 score: 2.5 bits; conditional E-value: 1.1 TPR_14 4 wlalarallalGdpdeAlelleral 28 + l++a+ d+ +A+e++e+ l FUN_000342-T1 183 YFNLGNAYDSISDFPKAIECYEKSL 207 677999999999**********976 PP == domain 6 score: 10.2 bits; conditional E-value: 0.0036 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+l l+ a+ +Gd+ +A e++e+ l FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKSLN 248 68999*******************9876 PP == domain 7 score: 11.9 bits; conditional E-value: 0.001 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+ l+ a+ +Gd+ +A+e++e+ l FUN_000342-T1 261 DAYFNLGSAHKSQGDFPKAIEYYEKSLN 288 578899******************9876 PP == domain 8 score: 5.3 bits; conditional E-value: 0.14 TPR_14 3 awlalarallalGdpdeAlelleralaldP 32 a+ l+ a+ d+ +A+e++e+ l + FUN_000342-T1 302 AYFNLGIAYKSHRDFPRAIECYEKSLNIAW 331 5677999****************9887655 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.1 0.0 0.00058 0.25 34 114 .. 16 97 .. 4 100 .. 0.86 2 ? 6.6 0.0 0.013 5.7 40 118 .. 100 178 .. 95 190 .. 0.84 3 ! 27.7 0.0 5e-09 2.1e-06 16 117 .. 195 297 .. 189 346 .. 0.88 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00058 TPR_MalT 34 ddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesk 114 + ar + a ++lG+a++ + dl +A + +++ +ar+ ++ + +++ + ++ +A+e y++ l a++++ FUN_000342-T1 16 EGDRARqGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNIARDAG 97 4444555999*****************************9999987788888999****99****************99876 PP == domain 2 score: 6.6 bits; conditional E-value: 0.013 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqeskleal 118 + a+l+lG a+ qg + +A + +++ +a +a++ + a+ ++ + ++ +A+e y++ l a e++ +a+ FUN_000342-T1 100 GDAYLNLGIAYKSQGGFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRAT 178 5688999999999999999999999999999888888888888888888888888999999999999999998877665 PP == domain 3 score: 27.7 bits; conditional E-value: 5e-09 TPR_MalT 16 eaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 ++++a+e ++ L++ e + ar + a+l+lG a+ qgd+++A + +++ +ar+a + + a+ ++ + qG++ +A+e y++ l a FUN_000342-T1 195 DFPKAIECYEKSLNIAMEAGHQAReGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 290 789999999**************************************************99999999***************************** PP TPR_MalT 111 qesklea 117 +e++ +a FUN_000342-T1 291 REEGDRA 297 *998775 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.8 7.6e+02 33 59 .. 27 53 .. 19 63 .. 0.71 2 ? 5.3 0.0 0.065 28 4 57 .. 32 84 .. 29 97 .. 0.83 3 ? 7.6 0.0 0.013 5.6 7 58 .. 75 129 .. 69 140 .. 0.83 4 ! 9.9 0.0 0.0024 1 3 57 .. 148 201 .. 146 218 .. 0.87 5 ! 14.9 0.0 6.9e-05 0.03 7 66 .. 192 257 .. 186 260 .. 0.90 6 ? 5.4 0.0 0.063 27 31 66 .. 262 297 .. 257 299 .. 0.84 7 ! 9.4 0.0 0.0036 1.5 3 66 .. 268 337 .. 266 342 .. 0.87 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.8 TPR_9 33 rdrGllyaqlgcleaAladLeaylala 59 ++ G +y+ l +l +A+++ e+ l +a FUN_000342-T1 27 FNLGTAYHSLSDLPKAIDYYEKSLNIA 53 567778888888888888877766555 PP == domain 2 score: 5.3 bits; conditional E-value: 0.065 TPR_9 4 iyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y++ dl++a+ ++e l +a + +++r G +y++lg+ ++ d+ ++++ FUN_000342-T1 32 AYHSLSDLPKAIDYYEKSLNIA-RKVGDRATEGNIYFNLGNAYDSISDFPKAIE 84 6788899999999999999996.8999999999999999999999999987775 PP == domain 3 score: 7.6 bits; conditional E-value: 0.013 TPR_9 7 reedleralavverllll...aPddpeerrdrGllyaqlgcleaAladLeaylal 58 + d+++a++++e l + a d+ + + + G++y +g + +A+++ ++ l + FUN_000342-T1 75 SISDFPKAIECYEKSLNIardAGDQGDAYLNLGIAYKSQGGFPKAIECYKKSLNI 129 5579************998877889999*******************99877654 PP == domain 4 score: 9.9 bits; conditional E-value: 0.0024 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y + d+++a++++e l +a ++++r G +y++lg+ ++ d+ ++++ FUN_000342-T1 148 IAYKSHSDFPKAIECYEKSLNIAS-EAGDRATEGNVYFNLGNAYDSISDFPKAIE 201 6788999***************97.689**************9999999988776 PP == domain 5 score: 14.9 bits; conditional E-value: 6.9e-05 TPR_9 7 reedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 + d+++a++++e l + + ++ + + + G++y +g++ +A ++ e+ l +a +a d++ FUN_000342-T1 192 SISDFPKAIECYEKSLNIameaghQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRA 257 55799*************9999999999999***************************99999986 PP == domain 6 score: 5.4 bits; conditional E-value: 0.063 TPR_9 31 errdrGllyaqlgcleaAladLeaylalapdapdae 66 +++ G+++ +g++ +A+++ e+ l +a + d++ FUN_000342-T1 262 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRA 297 67899999999**********999998888777665 PP == domain 7 score: 9.4 bits; conditional E-value: 0.0036 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 ++ ++ d+++a++++e l + + ++ + +++ G++y +++ +A+++ e+ l +a +a d++ FUN_000342-T1 268 SAHKSQGDFPKAIEYYEKSLNIareegdRAREGTAYFNLGIAYKSHRDFPRAIECYEKSLNIAWEAGDRA 337 5688899999999999999999999888899999999******************999988887777765 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.038 16 70 92 .. 37 59 .. 32 68 .. 0.84 2 ? 5.3 0.0 0.075 32 70 94 .. 77 101 .. 66 144 .. 0.71 3 ? 4.2 0.0 0.16 70 69 92 .. 153 176 .. 149 185 .. 0.84 4 ? 3.3 0.0 0.31 1.3e+02 69 90 .. 193 214 .. 187 225 .. 0.81 5 ? 6.1 0.0 0.041 17 68 92 .. 232 256 .. 229 269 .. 0.87 6 ? 7.9 0.0 0.012 5 68 89 .. 272 293 .. 268 301 .. 0.86 7 ? 1.8 0.0 0.87 3.7e+02 69 92 .. 313 336 .. 308 358 .. 0.83 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.038 DUF7018 70 kllekaidhyekslklieeavek 92 +l kaid+yeksl++++++ ++ FUN_000342-T1 37 SDLPKAIDYYEKSLNIARKVGDR 59 5889************9987655 PP == domain 2 score: 5.3 bits; conditional E-value: 0.075 DUF7018 70 kllekaidhyekslklieeavekkd 94 ++ kai+ yeksl+++++a ++ d FUN_000342-T1 77 SDFPKAIECYEKSLNIARDAGDQGD 101 6888999999999999888877633 PP == domain 3 score: 4.2 bits; conditional E-value: 0.16 DUF7018 69 qkllekaidhyekslklieeavek 92 ++ kai+ yeksl+++ ea ++ FUN_000342-T1 153 HSDFPKAIECYEKSLNIASEAGDR 176 57999*************998666 PP == domain 4 score: 3.3 bits; conditional E-value: 0.31 DUF7018 69 qkllekaidhyekslklieeav 90 ++ kai+ yeksl+++ ea FUN_000342-T1 193 ISDFPKAIECYEKSLNIAMEAG 214 57999***********988874 PP == domain 5 score: 6.1 bits; conditional E-value: 0.041 DUF7018 68 vqkllekaidhyekslklieeavek 92 q +++ka + yeksl++++ea ++ FUN_000342-T1 232 SQGDFTKASECYEKSLNIAREASDR 256 699*****************99876 PP == domain 6 score: 7.9 bits; conditional E-value: 0.012 DUF7018 68 vqkllekaidhyekslklieea 89 q ++ kai++yeksl++++e FUN_000342-T1 272 SQGDFPKAIEYYEKSLNIAREE 293 799**************99875 PP == domain 7 score: 1.8 bits; conditional E-value: 0.87 DUF7018 69 qkllekaidhyekslklieeavek 92 +++ +ai+ yeksl+++ ea ++ FUN_000342-T1 313 HRDFPRAIECYEKSLNIAWEAGDR 336 57999***********99887655 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.0 0.0 0.00019 0.081 205 251 .. 3 49 .. 1 56 [. 0.89 2 ? 5.1 0.0 0.024 10 101 142 .. 47 89 .. 46 96 .. 0.81 3 ! 9.3 0.1 0.0013 0.55 205 251 .. 120 166 .. 118 170 .. 0.94 4 ? 6.3 0.0 0.01 4.3 101 142 .. 164 206 .. 162 213 .. 0.63 5 ! 13.6 0.2 6.5e-05 0.027 91 142 .. 234 286 .. 207 292 .. 0.69 6 ? 4.9 0.1 0.027 11 101 143 .. 284 327 .. 283 335 .. 0.79 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00019 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy + l+ a+e + +++ ac+ l+ y + ++ +ai+++ ++ FUN_000342-T1 3 IECYEKSLDIAREEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKS 49 6799999999999999999999**********************986 PP == domain 2 score: 5.1 bits; conditional E-value: 0.024 TPR_IF140-IFT172 101 dkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 +k+l++a+k dr + y+n + ++ d+ +ai+ yeks FUN_000342-T1 47 EKSLNIARKVgDRATEGNIYFNLGNAYDSISDFPKAIECYEKS 89 6777888764388888999999999999999999999999987 PP == domain 3 score: 9.3 bits; conditional E-value: 0.0013 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy++ l+ a e +++++ a + l+ y ++ ++ +ai+ + ++ FUN_000342-T1 120 IECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKS 166 68****************************************99875 PP == domain 4 score: 6.3 bits; conditional E-value: 0.01 TPR_IF140-IFT172 101 dkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 +k+l++a++ dr + y+n + ++ d+ +ai+ yeks FUN_000342-T1 164 EKSLNIASEaGDRATEGNVYFNLGNAYDSISDFPKAIECYEKS 206 4555555431467777777777777777777777777777776 PP == domain 5 score: 13.6 bits; conditional E-value: 6.5e-05 TPR_IF140-IFT172 91 nklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 ++ +as+ ++k+l++a++ +dr + ++y+n ++gd+ +ai++yeks FUN_000342-T1 234 GDFTKASECYEKSLNIAREaSDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKS 286 45666666677777777542677777777777777777777777777777776 PP == domain 6 score: 4.9 bits; conditional E-value: 0.027 TPR_IF140-IFT172 101 dkalevaek.kdrihlrktyynyakhleakgdieeaiklyekse 143 +k+l++a++ dr + ++y+n +++d+ +ai+ yeks FUN_000342-T1 284 EKSLNIAREeGDRAREGTAYFNLGIAYKSHRDFPRAIECYEKSL 327 67788885415899999999999999999999999999999985 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.11 45 20 63 .. 7 50 .. 2 60 .. 0.82 2 ? 6.6 0.0 0.019 8.1 39 78 .. 66 105 .. 61 106 .. 0.83 3 ? 2.2 0.0 0.43 1.9e+02 37 66 .. 101 130 .. 96 138 .. 0.85 4 ? 4.5 0.1 0.081 34 37 67 .. 141 171 .. 118 178 .. 0.79 5 ! 8.0 0.0 0.0069 3 39 72 .. 183 216 .. 171 220 .. 0.90 6 ! 13.9 0.2 0.00011 0.046 37 138 .. 221 325 .. 217 332 .. 0.90 7 ? 5.7 0.0 0.036 15 16 87 .. 280 351 .. 273 363 .. 0.73 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.11 RPN7 20 eaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 e+ l+ a+e+ ra +l+ y++ dl +A+++ye+ + FUN_000342-T1 7 EKSLDIAREEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSL 50 6666667777777777889999*******************976 PP == domain 2 score: 6.6 bits; conditional E-value: 0.019 RPN7 39 ledlaehyakigdlenAlkayerarekttslghkidllln 78 + +l++ y +i d+ +A+++ye+ ++ + +g d +ln FUN_000342-T1 66 YFNLGNAYDSISDFPKAIECYEKSLNIARDAGDQGDAYLN 105 66899******************98877777776666665 PP == domain 3 score: 2.2 bits; conditional E-value: 0.43 RPN7 37 raledlaehyakigdlenAlkayerarekt 66 +a+++l+ y + g + +A+++y++ ++ + FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNIA 130 689999999***************987655 PP == domain 4 score: 4.5 bits; conditional E-value: 0.081 RPN7 37 raledlaehyakigdlenAlkayerarektt 67 +a+ +l+ y ++ d+ +A+++ye+ ++ ++ FUN_000342-T1 141 DAYFNLGIAYKSHSDFPKAIECYEKSLNIAS 171 678899999***************9887665 PP == domain 5 score: 8.0 bits; conditional E-value: 0.0069 RPN7 39 ledlaehyakigdlenAlkayerarekttslghk 72 + +l++ y +i d+ +A+++ye+ ++ ++ +gh FUN_000342-T1 183 YFNLGNAYDSISDFPKAIECYEKSLNIAMEAGHQ 216 67899*******************9999999886 PP == domain 6 score: 13.9 bits; conditional E-value: 0.00011 RPN7 37 raledlaehyakigdlenAlkayer...arekttslghkidlllnlirvgiffndwalvskylekaksliekggdwerrnrlkvyeGlaalairkf 129 +a+++l+ y + gd+++A ++ye+ + ++++ d ++nl +d+ ++ +y ek ++ + gd+ r+ G+a+ + r+f FUN_000342-T1 221 DAYLNLGIAYKSQGDFTKASECYEKslnIAREASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRAREGTAYFNLGIAYKSHRDF 316 57999999****************9444455666777788******************************************************** PP RPN7 130 keAakllld 138 +A ++ + FUN_000342-T1 317 PRAIECYEK 325 ***988755 PP == domain 7 score: 5.7 bits; conditional E-value: 0.036 RPN7 16 leeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffn 87 +e e+ l+ a+e+ +a+ +l+ y ++ d+ +A+++ye+ ++ + +g + + +++gi+++ FUN_000342-T1 280 IEYYEKSLNIAREEGDRAREGTAYFNLGIAYKSHRDFPRAIECYEKSLNIAWEAGDRAREGKTYLNLGIALK 351 556677777777777777777888899999999999999999999988877777777666666666666655 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.015 6.5 21 76 .. 6 61 .. 1 71 [. 0.90 2 ? 1.2 0.0 1.3 5.7e+02 47 74 .. 72 99 .. 63 106 .. 0.80 3 ? 1.4 0.0 1.2 4.9e+02 40 73 .. 102 135 .. 76 139 .. 0.54 4 ? 4.1 0.0 0.17 71 12 75 .. 114 177 .. 102 180 .. 0.80 5 ! 10.6 0.2 0.0015 0.62 12 75 .. 194 257 .. 183 258 .. 0.94 6 ? 6.9 0.0 0.021 8.9 40 75 .. 262 297 .. 261 299 .. 0.94 7 ? 1.2 0.0 1.3 5.4e+02 50 87 .. 319 356 .. 300 359 .. 0.64 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.015 ANAPC5 21 LhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 + D++ ++ ++ + a++nl + ++++++ +A++ e + ++Ar +D a+ FUN_000342-T1 6 YEKSLDIAREEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRAT 61 5567899999999999999*******************************999875 PP == domain 2 score: 1.2 bits; conditional E-value: 1.3 ANAPC5 47 lhadfghneeAvkaieeaiklArenkDt 74 + ++++ +A++ e + ++Ar+ +D+ FUN_000342-T1 72 AYDSISDFPKAIECYEKSLNIARDAGDQ 99 556667778999999*********9997 PP == domain 3 score: 1.4 bits; conditional E-value: 1.2 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkD 73 a lnl i + + g +A++ + + ++A e +D FUN_000342-T1 102 AYLNLGIAYKSQGGFPKAIECYKKSLNIAIEAGD 135 3455555555555555555555555555555555 PP == domain 4 score: 4.1 bits; conditional E-value: 0.17 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 + +++a+++ + ++++ ++ + a +nl i + + ++ +A++ e + ++A e +D a FUN_000342-T1 114 GGFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRA 177 5577777777777777777777777788899999999999999999999999999999999976 PP == domain 5 score: 10.6 bits; conditional E-value: 0.0015 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 +d+++a+++ + ++++ ++ + a lnl i + + g+ +A + e + ++Are +D a FUN_000342-T1 194 SDFPKAIECYEKSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRA 257 6999999999999999999999999999*********************************975 PP == domain 6 score: 6.9 bits; conditional E-value: 0.021 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDta 75 a +nl + h + g+ +A++ e + ++Are++D a FUN_000342-T1 262 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRA 297 679999***************************975 PP == domain 7 score: 1.2 bits; conditional E-value: 1.3 ANAPC5 50 dfghneeAvkaieeaiklArenkDtacLnlalswllel 87 +++++e++++ ea Are k L +al ++ + FUN_000342-T1 319 AIECYEKSLNIAWEAGDRAREGKTYLNLGIALKSHSDF 356 33677777777777777777777777777776666666 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.049 21 151 174 .. 39 62 .. 2 65 .. 0.80 2 ? 2.6 0.0 0.34 1.5e+02 149 173 .. 77 101 .. 66 103 .. 0.80 3 ? 4.4 0.0 0.094 40 135 175 .. 101 140 .. 100 142 .. 0.91 4 ? 5.6 0.0 0.042 18 135 174 .. 141 179 .. 140 182 .. 0.90 5 ? 4.3 0.0 0.1 45 143 175 .. 189 220 .. 181 222 .. 0.78 6 ? 6.7 0.1 0.019 8 135 175 .. 221 260 .. 220 262 .. 0.92 7 ? 5.4 0.0 0.048 20 135 174 .. 261 299 .. 260 302 .. 0.91 8 ? 4.1 0.0 0.12 52 136 174 .. 302 339 .. 301 342 .. 0.88 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.049 DUF7380 151 wvdalkrleRAlqlaaqlgkrkee 174 +a++++e++l +a+++g+r++e FUN_000342-T1 39 LPKAIDYYEKSLNIARKVGDRATE 62 56899***************9987 PP == domain 2 score: 2.6 bits; conditional E-value: 0.34 DUF7380 149 eewvdalkrleRAlqlaaqlgkrke 173 + +a++++e++l +a+ +g++++ FUN_000342-T1 77 SDFPKAIECYEKSLNIARDAGDQGD 101 668899*************999875 PP == domain 3 score: 4.4 bits; conditional E-value: 0.094 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ +++ + +a+++++++l +a ++g++++e FUN_000342-T1 101 DAYLNLGIAYKSQ-GGFPKAIECYKKSLNIAIEAGDQAREG 140 7999999999999.999******************999875 PP == domain 4 score: 5.6 bits; conditional E-value: 0.042 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daY + ++ + +a++++e++l +a ++g+r++e FUN_000342-T1 141 DAYFNLGIAYKSH-SDFPKAIECYEKSLNIASEAGDRATE 179 6899999999998.9999******************9987 PP == domain 5 score: 4.3 bits; conditional E-value: 0.1 DUF7380 143 eledgseewvdalkrleRAlqlaaqlgkrkeep 175 ++ + +a++++e++l +a+++g++++e FUN_000342-T1 189 AYDSI-SDFPKAIECYEKSLNIAMEAGHQAREG 220 44554.77899****************999875 PP == domain 6 score: 6.7 bits; conditional E-value: 0.019 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ +++ +++a +++e++l +a+++ +r++e FUN_000342-T1 221 DAYLNLGIAYKSQ-GDFTKASECYEKSLNIAREASDRAREG 260 79***99999999.999******************999875 PP == domain 7 score: 5.4 bits; conditional E-value: 0.048 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daY + + ++++ + +a++++e++l +a++ g+r++e FUN_000342-T1 261 DAYFNLGSAHKSQ-GDFPKAIEYYEKSLNIAREEGDRARE 299 7999999999999.999****************9999887 PP == domain 8 score: 4.1 bits; conditional E-value: 0.12 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aY + ++ + + +a++++e++l +a ++g+r++e FUN_000342-T1 302 AYFNLGIAYKSH-RDFPRAIECYEKSLNIAWEAGDRARE 339 788888888888.9999*****************99987 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 1.1 4.7e+02 19 32 .. 38 51 .. 23 62 .. 0.83 2 ? 4.9 0.1 0.095 41 13 32 .. 72 91 .. 66 96 .. 0.87 3 ? 5.4 0.0 0.065 28 9 33 .. 105 129 .. 98 141 .. 0.81 4 ? 4.3 0.0 0.14 59 11 32 .. 147 168 .. 138 179 .. 0.82 5 ? 6.5 0.0 0.029 12 13 37 .. 189 213 .. 183 226 .. 0.83 6 ? 4.5 0.1 0.12 52 9 33 .. 225 249 .. 218 262 .. 0.81 7 ? 5.0 0.0 0.085 36 16 32 .. 272 288 .. 262 289 .. 0.88 8 ? 3.9 0.0 0.19 83 5 32 .. 301 328 .. 298 333 .. 0.84 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 1.1 MIT 19 nyeeAlelYkeale 32 + +A+++Y+++l+ FUN_000342-T1 38 DLPKAIDYYEKSLN 51 6789*******997 PP == domain 2 score: 4.9 bits; conditional E-value: 0.095 MIT 13 eeDnagnyeeAlelYkeale 32 +D+ ++ +A+e+Y+++l+ FUN_000342-T1 72 AYDSISDFPKAIECYEKSLN 91 5789999**********997 PP == domain 3 score: 5.4 bits; conditional E-value: 0.065 MIT 9 kkAveeDnagnyeeAlelYkealel 33 + + + ++g + +A+e+Yk++l+ FUN_000342-T1 105 NLGIAYKSQGGFPKAIECYKKSLNI 129 5667777889999*********985 PP == domain 4 score: 4.3 bits; conditional E-value: 0.14 MIT 11 AveeDnagnyeeAlelYkeale 32 + + + ++ +A+e+Y+++l+ FUN_000342-T1 147 GIAYKSHSDFPKAIECYEKSLN 168 56666788999********997 PP == domain 5 score: 6.5 bits; conditional E-value: 0.029 MIT 13 eeDnagnyeeAlelYkealelLlqa 37 +D+ ++ +A+e+Y+++l+ + a FUN_000342-T1 189 AYDSISDFPKAIECYEKSLNIAMEA 213 5789999************987766 PP == domain 6 score: 4.5 bits; conditional E-value: 0.12 MIT 9 kkAveeDnagnyeeAlelYkealel 33 + + + ++g++ +A e+Y+++l+ FUN_000342-T1 225 NLGIAYKSQGDFTKASECYEKSLNI 249 566777889*************986 PP == domain 7 score: 5.0 bits; conditional E-value: 0.085 MIT 16 nagnyeeAlelYkeale 32 ++g++ +A+e+Y+++l+ FUN_000342-T1 272 SQGDFPKAIEYYEKSLN 288 5799**********997 PP == domain 8 score: 3.9 bits; conditional E-value: 0.19 MIT 5 lelvkkAveeDnagnyeeAlelYkeale 32 ++++ + + + ++ A+e+Y+++l+ FUN_000342-T1 301 TAYFNLGIAYKSHRDFPRAIECYEKSLN 328 5667777888889999*********997 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.5 6.5e+02 20 33 .. 42 55 .. 36 58 .. 0.68 2 ? 3.7 0.0 0.14 61 16 30 .. 78 92 .. 74 95 .. 0.83 3 ? 3.2 0.0 0.21 92 17 30 .. 116 129 .. 112 131 .. 0.92 4 ? 3.5 0.0 0.16 69 16 30 .. 155 169 .. 152 173 .. 0.88 5 ? 3.6 0.0 0.16 66 16 30 .. 195 209 .. 190 212 .. 0.82 6 ? 3.0 0.0 0.24 1e+02 17 31 .. 236 250 .. 232 254 .. 0.84 7 ? 4.9 0.0 0.062 27 17 30 .. 276 289 .. 272 293 .. 0.85 8 ? 1.7 0.0 0.63 2.7e+02 17 30 .. 316 329 .. 315 330 .. 0.92 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.5 SHNi-TPR 20 AvkDlrkaLeLree 33 A+ ++k+L++ ++ FUN_000342-T1 42 AIDYYEKSLNIARK 55 44457888888665 PP == domain 2 score: 3.7 bits; conditional E-value: 0.14 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000342-T1 78 DFPKAIECYEKSLNI 92 589999999999998 PP == domain 3 score: 3.2 bits; conditional E-value: 0.21 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000342-T1 116 FPKAIECYKKSLNI 129 999**********8 PP == domain 4 score: 3.5 bits; conditional E-value: 0.16 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000342-T1 155 DFPKAIECYEKSLNI 169 5999*********98 PP == domain 5 score: 3.6 bits; conditional E-value: 0.16 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000342-T1 195 DFPKAIECYEKSLNI 209 588999999999987 PP == domain 6 score: 3.0 bits; conditional E-value: 0.24 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F+ A++ ++k+L++ FUN_000342-T1 236 FTKASECYEKSLNIA 250 9999*********95 PP == domain 7 score: 4.9 bits; conditional E-value: 0.062 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000342-T1 276 FPKAIEYYEKSLNI 289 9************9 PP == domain 8 score: 1.7 bits; conditional E-value: 0.63 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000342-T1 316 FPRAIECYEKSLNI 329 8999999*****98 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.15 66 189 214 .. 36 61 .. 3 69 .. 0.84 2 ? 2.4 0.0 0.34 1.4e+02 190 212 .. 77 99 .. 65 102 .. 0.89 3 ? 5.5 0.0 0.04 17 186 213 .. 150 177 .. 102 185 .. 0.80 4 ? 5.3 0.0 0.046 19 187 213 .. 151 177 .. 141 219 .. 0.76 5 ? 6.2 0.1 0.024 10 143 211 .. 188 255 .. 178 259 .. 0.64 6 ? 4.5 0.0 0.077 33 149 206 .. 274 330 .. 261 339 .. 0.48 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.15 ComR_TPR 189 kkdfkkAkelYqkaimfakllgdevL 214 d+ kA +Y+k++ a+ +gd + FUN_000342-T1 36 LSDLPKAIDYYEKSLNIARKVGDRAT 61 68999*****************9875 PP == domain 2 score: 2.4 bits; conditional E-value: 0.34 ComR_TPR 190 kdfkkAkelYqkaimfakllgde 212 df kA e+Y+k++ a+ gd+ FUN_000342-T1 77 SDFPKAIECYEKSLNIARDAGDQ 99 699**************988885 PP == domain 3 score: 5.5 bits; conditional E-value: 0.04 ComR_TPR 186 lkvkkdfkkAkelYqkaimfakllgdev 213 k + df kA e+Y+k++ a+ gd + FUN_000342-T1 150 YKSHSDFPKAIECYEKSLNIASEAGDRA 177 345889***************9999975 PP == domain 4 score: 5.3 bits; conditional E-value: 0.046 ComR_TPR 187 kvkkdfkkAkelYqkaimfakllgdev 213 k + df kA e+Y+k++ a+ gd + FUN_000342-T1 151 KSHSDFPKAIECYEKSLNIASEAGDRA 177 446678888888888888888777764 PP == domain 5 score: 6.2 bits; conditional E-value: 0.024 ComR_TPR 143 avllllkdyekleellkvlkei.idktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 ++ + d+ k e+ +++ +i ++ +++ + +l l y + df kA e+Y+k++ a+ d FUN_000342-T1 188 NAYDSISDFPKAIECYEKSLNIaMEAGHQAREGDAYLNLGIAYKS--QGDFTKASECYEKSLNIAREASD 255 555555555554444444444315555555556666666665655..99*************99986665 PP == domain 6 score: 4.5 bits; conditional E-value: 0.077 ComR_TPR 149 kdyekleellkvlkeiidktqdfqkk.pivlmlewkyylkvkkdfkkAkelYqkaimfa 206 d+ k e+ +++ +i ++ d + ++ l ++ k ++df +A e+Y+k++ a FUN_000342-T1 274 GDFPKAIEYYEKSLNIAREEGDRAREgTAYFNL--GIAYKSHRDFPRAIECYEKSLNIA 330 344444444444444444443333220222222..233334666666666666666665 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 6 2.6e+03 46 77 .. 29 57 .. 12 60 .. 0.69 2 ? 3.7 0.0 0.21 90 23 76 .. 80 133 .. 70 137 .. 0.70 3 ? 6.3 0.0 0.034 15 37 75 .. 137 172 .. 118 177 .. 0.76 4 ? 3.2 0.0 0.3 1.3e+02 36 77 .. 216 254 .. 188 257 .. 0.72 5 ! 10.5 0.0 0.0016 0.68 19 75 .. 233 292 .. 224 297 .. 0.73 6 ? -0.1 0.0 3.3 1.4e+03 39 73 .. 299 330 .. 294 337 .. 0.67 7 ? 0.3 0.0 2.5 1.1e+03 37 59 .. 337 359 .. 310 363 .. 0.77 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 6 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 lG ta+ + a+++ + lnia+ + FUN_000342-T1 29 LG---TAYHSLSDLPKAIDYYEKSLNIARKVG 57 34...444444455568999999999999875 PP == domain 2 score: 3.7 bits; conditional E-value: 0.21 Rapsyn_N 23 ekalrvWrkvl...kktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 ka+ + k l +++ d++d + lG+ a+ G + a+e ++ lnia e FUN_000342-T1 80 PKAIECYEKSLniaRDAGDQGDAYLNLGI---AYKSQGGFPKAIECYKKSLNIAIEA 133 57788888777222455556666666665...6667899999999999999999875 PP == domain 3 score: 6.3 bits; conditional E-value: 0.034 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaee 75 ++ +d + lG+ +++hs++ k e + lnia e FUN_000342-T1 137 AREGDAYFNLGIAYKSHSDFPKAI---ECYEKSLNIASE 172 678899999**********88855...555556666666 PP == domain 4 score: 3.2 bits; conditional E-value: 0.3 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeele 77 ++ +d + lG+ +++ ++ k e e + lnia+e FUN_000342-T1 216 QAREGDAYLNLGIAYKSQGDFTKASECYE---KSLNIAREAS 254 46778889999998888877777777665...5578888865 PP == domain 5 score: 10.5 bits; conditional E-value: 0.0016 Rapsyn_N 19 sndtekalrvWrkvl...kktsdredkfrllGylitahsemGkykealefslaqlniaee 75 + d +ka + k l +++sdr l ah G + a+e+ + lnia+e FUN_000342-T1 233 QGDFTKASECYEKSLniaREASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 292 556677777776666333556666555555666779***********************9 PP == domain 6 score: -0.1 bits; conditional E-value: 3.3 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlnia 73 + + lG+ +++h ++ + a+e + lnia FUN_000342-T1 299 EGTAYFNLGIAYKSHRDFPR---AIECYEKSLNIA 330 55666779999999999655...455555555555 PP == domain 7 score: 0.3 bits; conditional E-value: 2.5 Rapsyn_N 37 sdredkfrllGylitahsemGky 59 ++ + + lG+ +++hs++ k FUN_000342-T1 337 AREGKTYLNLGIALKSHSDFQKL 359 34555677799999999999885 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.024 10 2 31 .. 24 49 .. 23 51 .. 0.76 2 ? 4.0 0.0 0.28 1.2e+02 19 31 .. 77 89 .. 66 91 .. 0.79 3 ? 1.5 0.3 1.7 7.3e+02 3 31 .. 102 126 .. 100 128 .. 0.58 4 ? 4.5 0.1 0.19 80 19 31 .. 154 166 .. 140 168 .. 0.65 5 ? 4.1 0.0 0.26 1.1e+02 18 31 .. 193 206 .. 182 208 .. 0.78 6 ? -0.1 0.1 5.6 2.4e+03 3 29 .. 222 244 .. 220 253 .. 0.57 7 ? 7.8 0.1 0.017 7.4 3 31 .. 262 286 .. 260 288 .. 0.69 8 ? 4.4 0.0 0.21 90 19 31 .. 314 326 .. 301 328 .. 0.73 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.024 Sel1 2 eAqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG y + D kA+ +yek+ FUN_000342-T1 24 RACFNLGtA-Y-HS---LSDLPKAIDYYEKS 49 589999963.3.55...469999******96 PP == domain 2 score: 4.0 bits; conditional E-value: 0.28 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000342-T1 77 SDFPKAIECYEKS 89 6999*******96 PP == domain 3 score: 1.5 bits; conditional E-value: 1.7 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+ +LG ++ +g kA+e+y+k+ FUN_000342-T1 102 AYLNLGiA--YKSQGGF---PKAIECYKKS 126 55566643..2333333...3899999986 PP == domain 4 score: 4.5 bits; conditional E-value: 0.19 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000342-T1 154 SDFPKAIECYEKS 166 39999*****996 PP == domain 5 score: 4.1 bits; conditional E-value: 0.26 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000342-T1 193 ISDFPKAIECYEKS 206 56999*******96 PP == domain 6 score: -0.1 bits; conditional E-value: 5.6 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewye 29 A+ +LG + +G D kA e+ye FUN_000342-T1 222 AYLNLGiAYKSQG-----DFTKASECYE 244 6667774322333.....4455555555 PP == domain 7 score: 7.8 bits; conditional E-value: 0.017 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG + + D kA+e+yek+ FUN_000342-T1 262 AYFNLGsAHKSQ-----GDFPKAIEYYEKS 286 666666542233.....3999*******96 PP == domain 8 score: 4.4 bits; conditional E-value: 0.21 Sel1 19 kDpekAlewyekA 31 +D +A+e+yek+ FUN_000342-T1 314 RDFPRAIECYEKS 326 799********96 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 5.6 2.4e+03 26 54 .. 24 52 .. 17 60 .. 0.72 2 ? 2.4 0.0 0.68 2.9e+02 6 57 .. 38 95 .. 33 98 .. 0.77 3 ? 6.6 0.0 0.032 13 6 50 .. 78 125 .. 77 130 .. 0.80 4 ? -0.1 0.0 4.1 1.8e+03 23 50 .. 178 205 .. 151 219 .. 0.66 5 ! 9.8 0.0 0.0032 1.4 23 57 .. 218 252 .. 194 260 .. 0.75 6 ? 6.4 0.1 0.038 16 24 57 .. 259 292 .. 243 302 .. 0.70 7 ? 6.7 0.0 0.03 13 4 49 .. 273 324 .. 270 330 .. 0.77 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 5.6 TPR_19 26 earllLArallalgrldeAealLaalpaa 54 +a+ +L+ a+ l +l +A+ ++ ++ FUN_000342-T1 24 RACFNLGTAYHSLSDLPKAIDYYEKSLNI 52 67778888888888888887776665555 PP == domain 2 score: 2.4 bits; conditional E-value: 0.68 TPR_19 6 dydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaadpd 57 d+ +A+ ++e+ l ++ + ++ +L++a+ ++ +A++ ++ ++ ++d FUN_000342-T1 38 DLPKAIDYYEKSLNIARKvgdratEGNIYFNLGNAYDSISDFPKAIECYEKSLNIARD 95 5667788888877665444444458899999999**9999999999999988888777 PP == domain 3 score: 6.6 bits; conditional E-value: 0.032 TPR_19 6 dydeAlalLeqalaedPd...naearllLArallalgrldeAealLaa 50 d+ +A++ +e+ l ++ d +a+l+L+ a+ +g + +A++ ++ FUN_000342-T1 78 DFPKAIECYEKSLNIARDagdQGDAYLNLGIAYKSQGGFPKAIECYKK 125 677888888886655444445*********************998765 PP == domain 4 score: -0.1 bits; conditional E-value: 4.1 TPR_19 23 dnaearllLArallalgrldeAealLaa 50 + ++ +L++a+ ++ +A++ ++ FUN_000342-T1 178 TEGNVYFNLGNAYDSISDFPKAIECYEK 205 3677888888888888888888887766 PP == domain 5 score: 9.8 bits; conditional E-value: 0.0032 TPR_19 23 dnaearllLArallalgrldeAealLaalpaadpd 57 +a+l+L+ a+ +g++ +A++ ++ ++ +++ FUN_000342-T1 218 REGDAYLNLGIAYKSQGDFTKASECYEKSLNIARE 252 3789********************99998888776 PP == domain 6 score: 6.4 bits; conditional E-value: 0.038 TPR_19 24 naearllLArallalgrldeAealLaalpaadpd 57 +a+ +L+ a+ +g++ +A++ ++ ++ +++ FUN_000342-T1 259 EGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 292 5677888888888888888888877777666665 PP == domain 7 score: 6.7 bits; conditional E-value: 0.03 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAealLa 49 +gd+ +A++++e+ l ++ + a+ +L+ a+ ++ +A++ + FUN_000342-T1 273 QGDFPKAIEYYEKSLNIAREegdrarEGTAYFNLGIAYKSHRDFPRAIECYE 324 9************987766654566677788888888888888888887665 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.14 58 55 81 .. 68 94 .. 21 125 .. 0.56 2 ! 8.6 0.0 0.0051 2.2 55 153 .. 68 172 .. 55 177 .. 0.85 3 ! 10.8 0.0 0.0011 0.45 56 155 .. 186 294 .. 175 297 .. 0.79 4 ? 6.6 0.0 0.021 9 59 150 .. 229 289 .. 214 337 .. 0.52 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.14 TPR_CcmH_CycH 55 lLGriglslndaetAiqAfekAlklap 81 LG + s++d +Ai+ +ek+l++a FUN_000342-T1 68 NLGNAYDSISDFPKAIECYEKSLNIAR 94 344444455555555555555555544 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0051 TPR_CcmH_CycH 55 lLGriglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAiaaW 144 LG + s++d +Ai+ +ek+l++a + + Y ++ + +++ kA e +kk l+ ++ ++ +a+ l++ + ++ d+++Ai+ + FUN_000342-T1 68 NLGNAYDSISDFPKAIECYEKSLNIARDAGDQGDAYLNLGIAYKSQGGFPKAIECYKKSLNiaieagDQAREGDAYFNLGIAYKSHSDFPKAIECY 163 58889999999***********************************999999999999876433333567788999999****************9 PP TPR_CcmH_CycH 145 qkmlkllpa 153 +k l++ + FUN_000342-T1 164 EKSLNIASE 172 998887665 PP == domain 3 score: 10.8 bits; conditional E-value: 0.0011 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteikl...sYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s++d +Ai+ +ek+l++a + + + Y ++ + +++ d +kA+e ++k l+ + ++ +a+ l+ + +qgd+++Ai+ FUN_000342-T1 186 LGNAYDSISDFPKAIECYEKSLNIAMEAGHQARegdAYLNLGIAYKSQGDFTKASECYEKSLNiareasDRAREGDAYFNLGSAHKSQGDFPKAIE 281 8888899999999*********999887655542226999999999*********99999875222111344567899999*************** PP TPR_CcmH_CycH 143 aWqkmlkllpadd 155 +++k l++ ++ FUN_000342-T1 282 YYEKSLNIAREEG 294 ***9998877665 PP == domain 4 score: 6.6 bits; conditional E-value: 0.021 TPR_CcmH_CycH 59 iglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAiaaWqkmlkl 150 + s++d ++A + +ek+l++a + ++ + + +a+ l+ + +qgd+++Ai++++k l++ FUN_000342-T1 229 AYKSQGDFTKASECYEKSLNIAREASDRAR-------------------------------EGDAYFNLGSAHKSQGDFPKAIEYYEKSLNI 289 455555555555555555555544433322...............................2223333333333344444444444433333 PP >> ssDBP Phage single-stranded DNA-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.61 2.6e+02 26 48 .. 29 51 .. 14 62 .. 0.74 2 ? 2.0 0.0 0.67 2.9e+02 18 46 .. 62 89 .. 56 98 .. 0.77 3 ? 5.0 0.0 0.075 32 18 55 .. 99 135 .. 93 138 .. 0.86 4 ? 5.0 0.1 0.076 32 18 48 .. 139 168 .. 135 178 .. 0.80 5 ? 4.0 0.0 0.16 68 18 54 .. 179 214 .. 169 218 .. 0.80 6 ! 8.7 0.1 0.0054 2.3 18 46 .. 259 286 .. 246 297 .. 0.83 7 ? 4.8 0.0 0.088 37 18 54 .. 299 334 .. 291 338 .. 0.79 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.61 ssDBP 26 eafahledapfPqkisyyveskd 48 + a+ + + P+ i+yy +s + FUN_000342-T1 29 LGTAYHSLSDLPKAIDYYEKSLN 51 45567777789*******99954 PP == domain 2 score: 2.0 bits; conditional E-value: 0.67 ssDBP 18 kGnpYtmaeafahledapfPqkisyyves 46 +Gn Y ++ + a+ + +fP+ i+ y +s FUN_000342-T1 62 EGNIY-FNLGNAYDSISDFPKAIECYEKS 89 56766.566778888999******99988 PP == domain 3 score: 5.0 bits; conditional E-value: 0.075 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskdevlpaGe 55 +G++Y ++ + a++++ fP+ i+ y +s + ++aG+ FUN_000342-T1 99 QGDAY-LNLGIAYKSQGGFPKAIECYKKSLNIAIEAGD 135 67888.467899*****************999999998 PP == domain 4 score: 5.0 bits; conditional E-value: 0.076 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a+++ +fP+ i+ y +s + FUN_000342-T1 139 EGDAY-FNLGIAYKSHSDFPKAIECYEKSLN 168 57777.67899***************99955 PP == domain 5 score: 4.0 bits; conditional E-value: 0.16 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskdevlpaG 54 +Gn Y ++ + a+ + +fP+ i+ y +s + ++aG FUN_000342-T1 179 EGNVY-FNLGNAYDSISDFPKAIECYEKSLNIAMEAG 214 67777.566778888899********99988777777 PP == domain 6 score: 8.7 bits; conditional E-value: 0.0054 ssDBP 18 kGnpYtmaeafahledapfPqkisyyves 46 +G++Y ++ + ah+++ +fP+ i+yy +s FUN_000342-T1 259 EGDAY-FNLGSAHKSQGDFPKAIEYYEKS 286 67787.677889**************998 PP == domain 7 score: 4.8 bits; conditional E-value: 0.088 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskdevlpaG 54 +G +Y ++ + a+++ +fP+ i+ y +s + +aG FUN_000342-T1 299 EGTAY-FNLGIAYKSHRDFPRAIECYEKSLNIAWEAG 334 56666.67899***************99966555555 PP >> TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 8.1 3.5e+03 56 72 .. 37 53 .. 30 60 .. 0.76 2 ? 2.6 0.0 0.39 1.7e+02 56 71 .. 77 92 .. 70 103 .. 0.86 3 ? 0.6 0.0 1.6 6.9e+02 57 71 .. 115 129 .. 105 136 .. 0.79 4 ? 4.9 0.0 0.074 32 54 71 .. 152 169 .. 132 176 .. 0.76 5 ? 4.4 0.1 0.11 45 56 100 .. 194 236 .. 187 245 .. 0.67 6 ? 3.6 0.1 0.19 80 36 70 .. 247 288 .. 228 304 .. 0.63 7 ? 4.3 0.0 0.12 49 55 70 .. 313 328 .. 306 335 .. 0.84 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 8.1 TPR_BSK1_C 56 kdfktaiecytqfidag 72 d+ +ai++y + ++ FUN_000342-T1 37 SDLPKAIDYYEKSLNIA 53 57889999999887765 PP == domain 2 score: 2.6 bits; conditional E-value: 0.39 TPR_BSK1_C 56 kdfktaiecytqfida 71 df +aiecy + ++ FUN_000342-T1 77 SDFPKAIECYEKSLNI 92 69********998765 PP == domain 3 score: 0.6 bits; conditional E-value: 1.6 TPR_BSK1_C 57 dfktaiecytqfida 71 f +aiecy + ++ FUN_000342-T1 115 GFPKAIECYKKSLNI 129 599******998765 PP == domain 4 score: 4.9 bits; conditional E-value: 0.074 TPR_BSK1_C 54 rakdfktaiecytqfida 71 + df +aiecy + ++ FUN_000342-T1 152 SHSDFPKAIECYEKSLNI 169 368*********998876 PP == domain 5 score: 4.4 bits; conditional E-value: 0.11 TPR_BSK1_C 56 kdfktaiecytqfidagtmvsptvyarrslsylmsdkpqeALkda 100 df +aiecy + ++ +++ ar +yl + + ++ +d FUN_000342-T1 194 SDFPKAIECYEKSLNIA--MEAGHQAREGDAYLNLGIAYKSQGDF 236 59*********998754..44555566666666665555555555 PP == domain 6 score: 3.6 bits; conditional E-value: 0.19 TPR_BSK1_C 36 tqqmqetlnskkkgDaaFr.......akdfktaiecytqfid 70 + +e+ + ++gDa F+ + df +aie+y + ++ FUN_000342-T1 247 LNIAREASDRAREGDAYFNlgsahksQGDFPKAIEYYEKSLN 288 444556666666666666333222224588888888887765 PP == domain 7 score: 4.3 bits; conditional E-value: 0.12 TPR_BSK1_C 55 akdfktaiecytqfid 70 ++df aiecy + ++ FUN_000342-T1 313 HRDFPRAIECYEKSLN 328 79*********99876 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.1 43 5 28 .. 29 52 .. 25 56 .. 0.72 2 ? 3.3 0.0 0.29 1.2e+02 127 153 .] 64 90 .. 56 90 .. 0.84 3 ? -0.2 0.0 3.5 1.5e+03 135 153 .] 109 127 .. 103 132 .. 0.62 4 ? 2.2 0.0 0.66 2.8e+02 8 27 .. 149 168 .. 144 176 .. 0.59 5 ? 2.4 0.0 0.57 2.4e+02 127 153 .] 181 207 .. 168 207 .. 0.79 6 ? 2.4 0.0 0.55 2.3e+02 5 27 .. 186 208 .. 182 218 .. 0.68 7 ? -0.3 0.0 3.9 1.7e+03 133 153 .] 227 247 .. 220 256 .. 0.66 8 ? 6.4 0.0 0.032 14 6 30 .. 267 291 .. 263 298 .. 0.78 9 ? 1.9 0.0 0.8 3.4e+02 132 153 .] 306 327 .. 301 330 .. 0.75 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ + kAi+YYe+ l++ FUN_000342-T1 29 LGTAYHSLSDLPKAIDYYEKSLNI 52 566777777777888888888775 PP == domain 2 score: 3.3 bits; conditional E-value: 0.29 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 +i ++l++ + s +d+ kai++Y +L FUN_000342-T1 64 NIYFNLGNAYDSISDFPKAIECYEKSL 90 788899999999999999999998776 PP == domain 3 score: -0.2 bits; conditional E-value: 3.5 ARM_TT21_4th 135 haaserdyekaiklYkeAL 153 + s+ + kai++Yk +L FUN_000342-T1 109 AYKSQGGFPKAIECYKKSL 127 4555555666666666554 PP == domain 4 score: 2.2 bits; conditional E-value: 0.66 ARM_TT21_4th 8 alvktHqYkkAinYYeaalk 27 a+ ++ kAi+ Ye+ l+ FUN_000342-T1 149 AYKSHSDFPKAIECYEKSLN 168 44333356666666666665 PP == domain 5 score: 2.4 bits; conditional E-value: 0.57 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 ++ ++l++ + s +d+ kai++Y +L FUN_000342-T1 181 NVYFNLGNAYDSISDFPKAIECYEKSL 207 566788888888899999999998765 PP == domain 6 score: 2.4 bits; conditional E-value: 0.55 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ ++ kAi+ Ye+ l+ FUN_000342-T1 186 LGNAYDSISDFPKAIECYEKSLN 208 56666666667777777776665 PP == domain 7 score: -0.3 bits; conditional E-value: 3.9 ARM_TT21_4th 133 AehaaserdyekaiklYkeAL 153 + + s+ d++ka ++Y +L FUN_000342-T1 227 GIAYKSQGDFTKASECYEKSL 247 445566666666666666544 PP == domain 8 score: 6.4 bits; conditional E-value: 0.032 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalksse 30 G a ++ kAi+YYe+ l++ + FUN_000342-T1 267 GSAHKSQGDFPKAIEYYEKSLNIAR 291 55666666899********998765 PP == domain 9 score: 1.9 bits; conditional E-value: 0.8 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s+rd+ +ai++Y +L FUN_000342-T1 306 LGIAYKSHRDFPRAIECYEKSL 327 5566778888888888887665 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 7.2 3.1e+03 41 81 .. 8 48 .. 5 49 .. 0.68 2 ? 1.3 0.0 1.4 6e+02 7 56 .. 41 90 .. 35 92 .. 0.68 3 ? 6.6 0.0 0.032 14 5 50 .. 79 128 .. 75 133 .. 0.87 4 ? 6.6 0.1 0.031 13 3 59 .. 154 210 .. 152 215 .. 0.86 5 ! 8.4 0.1 0.0087 3.7 5 50 .. 196 248 .. 192 258 .. 0.82 6 ! 9.6 0.1 0.0038 1.6 2 50 .. 233 288 .. 232 307 .. 0.80 7 ? 2.9 0.0 0.46 2e+02 2 49 .. 273 326 .. 272 333 .. 0.56 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 7.2 ANAPC3 41 rAyellrkaklnekslgcryllAqcllkLkkykeAldaLek 81 + +++ r+ + + + ++++ l+ +++ L + +A+d +ek FUN_000342-T1 8 KSLDIAREEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEK 48 55566666666666666777778888888888888888776 PP == domain 2 score: 1.3 bits; conditional E-value: 1.4 ANAPC3 7 nAiflaerllaaepespedayllAqclflngqykrAyellrka.klneksl 56 Ai ++e+ l ++ d+ + ++ +f++g+ + + + ka +++eksl FUN_000342-T1 41 KAIDYYEKSL-NIARKVGDRATEGNIYFNLGNAYDSISDFPKAiECYEKSL 90 6788888888.7777777777777778877777766666666655555555 PP == domain 3 score: 6.6 bits; conditional E-value: 0.032 ANAPC3 5 yknAiflaerll..aaepespedayl.lAqclflngqykrAyellrka.k 50 + Ai ++e+ l a ++ + dayl l+ ++ ++g + +A+e +k+ + FUN_000342-T1 79 FPKAIECYEKSLniARDAGDQGDAYLnLGIAYKSQGGFPKAIECYKKSlN 128 6789********55599999999***88*****************99944 PP == domain 4 score: 6.6 bits; conditional E-value: 0.031 ANAPC3 3 hqyknAiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcr 59 ++ Ai ++e+ l + ++ d+ + ++++f++g+ + + + ka +++eksl+ + FUN_000342-T1 154 SDFPKAIECYEKSL-NIASEAGDRATEGNVYFNLGNAYDSISDFPKAiECYEKSLNIA 210 56789*********.999999999999********99999988888888888888765 PP == domain 5 score: 8.4 bits; conditional E-value: 0.0087 ANAPC3 5 yknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka.k 50 + Ai ++e+ l a ++ ++ dayl l+ ++ ++g++++A e +k+ + FUN_000342-T1 196 FPKAIECYEKSLniameAGHQAREGDAYLnLGIAYKSQGDFTKASECYEKSlN 248 5689999999997766557778888899978****************999943 PP == domain 6 score: 9.6 bits; conditional E-value: 0.0038 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka.k 50 ++++ A ++e+ l a+++ ++ day l+ ++ ++g++ +A+e+ +k+ + FUN_000342-T1 233 QGDFTKASECYEKSLniareASDRAREGDAYFnLGSAHKSQGDFPKAIEYYEKSlN 288 6778889999999997766546666666677659*****************99933 PP == domain 7 score: 2.9 bits; conditional E-value: 0.46 ANAPC3 2 nhqyknAiflaerll.....a.aepespedayllAqclflngqykrAyellrka 49 ++++ Ai ++e+ l + + +++ + + l+ ++ + ++ rA+e +k+ FUN_000342-T1 273 QGDFPKAIEYYEKSLniareEgDRAREGTAYFNLGIAYKSHRDFPRAIECYEKS 326 667888999999999333221222333333444566666666666666666655 PP >> Clathrin Region in Clathrin and VPS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 1.1 4.7e+02 106 124 .. 33 51 .. 26 54 .. 0.83 2 ? 3.7 0.0 0.15 65 75 115 .. 55 95 .. 52 107 .. 0.80 3 ? 5.0 0.0 0.06 26 79 111 .. 136 168 .. 127 190 .. 0.74 4 ? 2.3 0.0 0.41 1.8e+02 92 131 .. 189 226 .. 173 238 .. 0.71 5 ? -0.5 0.0 3.2 1.4e+03 91 114 .. 228 251 .. 214 276 .. 0.73 6 ? 0.1 0.0 2 8.6e+02 107 124 .. 271 288 .. 239 293 .. 0.78 7 ? 5.0 0.0 0.063 27 89 134 .. 306 349 .. 294 357 .. 0.76 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.1 Clathrin 106 lkknklykraieyavkasn 124 +++++++++ai+y++k+ n FUN_000342-T1 33 YHSLSDLPKAIDYYEKSLN 51 899999*******999866 PP == domain 2 score: 3.7 bits; conditional E-value: 0.15 Clathrin 75 kvaklcekaklyeealilYkknedwdeaisvlkknklykra 115 kv++++ + + y + +Y+ ++d+ +ai++++k ++ r+ FUN_000342-T1 55 KVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNIARD 95 788888888888777779*************7776665554 PP == domain 3 score: 5.0 bits; conditional E-value: 0.06 Clathrin 79 lcekaklyeealilYkknedwdeaisvlkknkl 111 + + + y + i+Yk ++d+ +ai++++k + FUN_000342-T1 136 QAREGDAYFNLGIAYKSHSDFPKAIECYEKSLN 168 55666777777899************9776433 PP == domain 4 score: 2.3 bits; conditional E-value: 0.41 Clathrin 92 lYkknedwdeaisvlkknklykraieyavkasnpelweel 131 +Y+ ++d+ +ai++++k +++ a+e+ +a+ + + +l FUN_000342-T1 189 AYDSISDFPKAIECYEK--SLNIAMEAGHQAREGDAYLNL 226 79999999999999776..677777766666666666555 PP == domain 5 score: -0.5 bits; conditional E-value: 3.2 Clathrin 91 ilYkknedwdeaisvlkknklykr 114 i+Yk d+++a ++++k ++ r FUN_000342-T1 228 IAYKSQGDFTKASECYEKSLNIAR 251 577777788887777555444444 PP == domain 6 score: 0.1 bits; conditional E-value: 2 Clathrin 107 kknklykraieyavkasn 124 k+ +++++aiey++k+ n FUN_000342-T1 271 KSQGDFPKAIEYYEKSLN 288 667899999999999866 PP == domain 7 score: 5.0 bits; conditional E-value: 0.063 Clathrin 89 alilYkknedwdeaisvlkknklykraieyavkasnpelweellea 134 + i+Yk + d+ +ai++++k +++ a+e+ +a+ +++ +l+ a FUN_000342-T1 306 LGIAYKSHRDFPRAIECYEK--SLNIAWEAGDRAREGKTYLNLGIA 349 5579************9777..788888888888888887776655 PP >> DUF7971 Family of unknown function (DUF7971) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.96 4.1e+02 25 71 .. 37 88 .. 32 100 .. 0.51 2 ? 1.5 0.0 1.1 4.8e+02 28 50 .. 117 139 .. 110 145 .. 0.85 3 ? 1.8 0.0 0.9 3.8e+02 23 50 .. 152 179 .. 149 185 .. 0.83 4 ? 2.9 0.0 0.41 1.7e+02 23 50 .. 192 219 .. 186 226 .. 0.83 5 ? 0.1 0.0 3.1 1.3e+03 23 50 .. 232 259 .. 229 264 .. 0.84 6 ? 2.5 0.0 0.56 2.4e+02 22 52 .. 271 301 .. 266 305 .. 0.84 7 ? 3.4 0.0 0.28 1.2e+02 23 51 .. 312 340 .. 309 348 .. 0.86 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.96 DUF7971 25 admqraveglerrlneaieeaddeeeaa.....savvdaierleerleryde 71 +d+ +a++ +e++ln a + d +e +++ d i + + +e y++ FUN_000342-T1 37 SDLPKAIDYYEKSLNIARKVGDRATEGNiyfnlGNAYDSISDFPKAIECYEK 88 5667777777777776655555444432111113344444444444444444 PP == domain 2 score: 1.5 bits; conditional E-value: 1.1 DUF7971 28 qraveglerrlneaieeaddeee 50 +a+e ++++ln aie+ d+ +e FUN_000342-T1 117 PKAIECYKKSLNIAIEAGDQARE 139 689*************9999877 PP == domain 3 score: 1.8 bits; conditional E-value: 0.9 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d +e FUN_000342-T1 152 SHSDFPKAIECYEKSLNIASEAGDRATE 179 578999***********99988877655 PP == domain 4 score: 2.9 bits; conditional E-value: 0.41 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 + +d+ +a+e +e++ln a+e+ ++ +e FUN_000342-T1 192 SISDFPKAIECYEKSLNIAMEAGHQARE 219 568999**************99877766 PP == domain 5 score: 0.1 bits; conditional E-value: 3.1 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 ++ d+++a e +e++ln a e++d +e FUN_000342-T1 232 SQGDFTKASECYEKSLNIAREASDRARE 259 5679999**********99999988776 PP == domain 6 score: 2.5 bits; conditional E-value: 0.56 DUF7971 22 eaaadmqraveglerrlneaieeaddeeeaa 52 +++ d+ +a+e +e++ln a ee d +e + FUN_000342-T1 271 KSQGDFPKAIEYYEKSLNIAREEGDRAREGT 301 5678999*************99999887765 PP == domain 7 score: 3.4 bits; conditional E-value: 0.28 DUF7971 23 aaadmqraveglerrlneaieeaddeeea 51 +++d+ ra+e +e++ln a e+ d +e FUN_000342-T1 312 SHRDFPRAIECYEKSLNIAWEAGDRAREG 340 67899***************999988775 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.11 47 7 47 .. 21 61 .. 18 76 .. 0.90 2 ? -0.7 0.0 2.7 1.1e+03 10 48 .. 101 139 .. 94 155 .. 0.87 3 ? 1.3 0.0 0.7 3e+02 6 46 .. 137 177 .. 132 186 .. 0.89 4 ! 8.0 0.1 0.006 2.5 6 48 .. 217 259 .. 212 262 .. 0.92 5 ! 7.6 0.1 0.0082 3.5 6 48 .. 257 299 .. 252 303 .. 0.92 6 ? 4.2 0.0 0.091 39 7 48 .. 298 339 .. 296 348 .. 0.92 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.11 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarlR 47 ++ a ++L++ ++ d+ +A Y + +l+ a+++++r FUN_000342-T1 21 RQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRAT 61 5678999***************************9999865 PP == domain 2 score: -0.7 bits; conditional E-value: 2.7 DUF6377 10 aallkLaellyeegdierAykYikvaledakfynarlRk 48 a l+L+ + +g + +A ++ k +l+ a +++ R+ FUN_000342-T1 101 DAYLNLGIAYKSQGGFPKAIECYKKSLNIAIEAGDQARE 139 688899999999999************999999999886 PP == domain 3 score: 1.3 bits; conditional E-value: 0.7 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarl 46 +e a ++L+ + + d+ +A ++ + +l+ a+ ++r FUN_000342-T1 137 AREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRA 177 5788999**************************99998875 PP == domain 4 score: 8.0 bits; conditional E-value: 0.006 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlRk 48 +e a l+L+ + +gd+++A+++ + +l+ a+ ++r R+ FUN_000342-T1 217 AREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRARE 259 689999********************************99996 PP == domain 5 score: 7.6 bits; conditional E-value: 0.0082 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlRk 48 +e a ++L++ +gd+ +A +Y + +l+ a+ ++r R+ FUN_000342-T1 257 AREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRARE 299 578999******************************9999996 PP == domain 6 score: 4.2 bits; conditional E-value: 0.091 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarlRk 48 +e +a ++L+ + + d+ rA ++ + +l+ a ++r R+ FUN_000342-T1 298 REGTAYFNLGIAYKSHRDFPRAIECYEKSLNIAWEAGDRARE 339 7999********************************999997 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.15 63 59 101 .. 48 90 .. 43 95 .. 0.92 2 ? 5.3 0.0 0.048 20 42 103 .. 106 169 .. 91 173 .. 0.78 3 ? 2.7 0.0 0.3 1.3e+02 59 100 .. 165 206 .. 146 208 .. 0.81 4 ? 7.4 0.0 0.011 4.5 59 101 .. 205 247 .. 185 252 .. 0.87 5 ? 0.5 0.0 1.4 5.8e+02 60 101 .. 286 327 .. 276 331 .. 0.84 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.15 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+++ ++a + + + +lg++ + +++ a ec+ek+ FUN_000342-T1 48 KSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSL 90 57999***********************************985 PP == domain 2 score: 5.3 bits; conditional E-value: 0.048 TPR_COPA_B 42 LevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekakdl 103 L ++ ++ F a++ ++l++a e ++a++ + + +lg + +++++ a ec+ek+ ++ FUN_000342-T1 106 LGIAYKSQGGFPKAIECykKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNI 169 555555566666666642267999***9*******************************98765 PP == domain 3 score: 2.7 bits; conditional E-value: 0.3 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecleka 100 ++l++a e ++a + + + +lg++ + +++ a ec+ek+ FUN_000342-T1 165 KSLNIASEAGDRATEGNVYFNLGNAYDSISDFPKAIECYEKS 206 579999999999999999*********************986 PP == domain 4 score: 7.4 bits; conditional E-value: 0.011 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+e ++a++ + + +lg + ++g+++ a+ec+ek+ FUN_000342-T1 205 KSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKSL 247 6799************************************985 PP == domain 5 score: 0.5 bits; conditional E-value: 1.4 TPR_COPA_B 60 klevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 +l++a+e ++a++ + + +lg + ++ ++ a ec+ek+ FUN_000342-T1 286 SLNIAREEGDRAREGTAYFNLGIAYKSHRDFPRAIECYEKSL 327 57777777778888889999999999************9975 PP >> TPR_IF140_C IF140 C-terminal TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 1.1 4.8e+02 22 73 .. 40 89 .. 34 96 .. 0.69 2 ? 0.7 0.0 2.1 9.1e+02 16 41 .. 74 99 .. 70 129 .. 0.75 3 ! 10.5 0.0 0.0019 0.83 19 122 .. 154 245 .. 148 247 .. 0.82 4 ? 6.8 0.0 0.029 12 93 122 .. 216 245 .. 191 287 .. 0.48 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 1.1 TPR_IF140_C 22 ekAlgalkealkclskakeksekekekkleelkekielikkfveakklyeed 73 kA++ ++++l++ k+ ++ ++ + + +l + + i+ f +a ++ye++ FUN_000342-T1 40 PKAIDYYEKSLNIARKVGDRA--TEGNIYFNLGNAYDSISDFPKAIECYEKS 89 578888888888888877653..34556667777777777777777777764 PP == domain 2 score: 0.7 bits; conditional E-value: 2.1 TPR_IF140_C 16 deyqdYekAlgalkealkclskakek 41 d d+ kA+++++++l++ a ++ FUN_000342-T1 74 DSISDFPKAIECYEKSLNIARDAGDQ 99 56678888888888888877766554 PP == domain 3 score: 10.5 bits; conditional E-value: 0.0019 TPR_IF140_C 19 qdYekAlgalkealkclskakeksekekekkleelkekielikkfveakklyeedpeealkqceeLleepdleeavRlgDvyalliehyvkqgnfk 114 d+ kA+++++++l++ s+a ++ ++ + + +l + + i+ f +a ++ye++ + a+++ + R gD y l +y +qg+f+ FUN_000342-T1 154 SDFPKAIECYEKSLNIASEAGDRA--TEGNVYFNLGNAYDSISDFPKAIECYEKSLNIAMEAG----------HQAREGDAYLNLGIAYKSQGDFT 237 699999999999999999999764..4566778999999*********999999988888554..........34588999999999999999999 PP TPR_IF140_C 115 kAyellee 122 kA e+ e+ FUN_000342-T1 238 KASECYEK 245 99888775 PP == domain 4 score: 6.8 bits; conditional E-value: 0.029 TPR_IF140_C 93 avRlgDvyalliehyvkqgnfkkAyellee 122 R gD y l +y +qg+f+kA e+ e+ FUN_000342-T1 216 QAREGDAYLNLGIAYKSQGDFTKASECYEK 245 334444444444444444444444444332 PP >> Glyoxalase Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.19 83 10 27 .. 37 54 .. 35 72 .. 0.83 2 ? 1.3 0.0 1.4 6.1e+02 10 25 .. 77 92 .. 75 109 .. 0.88 3 ? 0.5 0.0 2.5 1.1e+03 10 25 .. 154 169 .. 152 183 .. 0.89 4 ? 2.5 0.0 0.58 2.5e+02 10 31 .. 194 215 .. 192 240 .. 0.81 5 ? -1.4 0.0 9.5 4.1e+03 10 30 .. 234 254 .. 232 272 .. 0.77 6 ? 2.8 0.0 0.49 2.1e+02 10 30 .. 274 294 .. 269 309 .. 0.81 7 ? 0.1 0.0 3.5 1.5e+03 10 25 .. 314 329 .. 312 345 .. 0.87 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.19 Glyoxalase 10 gdleksldFYtevLGfkl 27 +dl+k++d+Y++ L+ FUN_000342-T1 37 SDLPKAIDYYEKSLNIAR 54 69**********999765 PP == domain 2 score: 1.3 bits; conditional E-value: 1.4 Glyoxalase 10 gdleksldFYtevLGf 25 +d +k++++Y++ L+ FUN_000342-T1 77 SDFPKAIECYEKSLNI 92 799*********9986 PP == domain 3 score: 0.5 bits; conditional E-value: 2.5 Glyoxalase 10 gdleksldFYtevLGf 25 +d +k++++Y++ L+ FUN_000342-T1 154 SDFPKAIECYEKSLNI 169 6999********9985 PP == domain 4 score: 2.5 bits; conditional E-value: 0.58 Glyoxalase 10 gdleksldFYtevLGfklveet 31 +d +k++++Y++ L+ + + FUN_000342-T1 194 SDFPKAIECYEKSLNIAMEAGH 215 799***********98876655 PP == domain 5 score: -1.4 bits; conditional E-value: 9.5 Glyoxalase 10 gdleksldFYtevLGfklvee 30 gd k+ ++Y++ L+ + FUN_000342-T1 234 GDFTKASECYEKSLNIAREAS 254 688999999*99999876655 PP == domain 6 score: 2.8 bits; conditional E-value: 0.49 Glyoxalase 10 gdleksldFYtevLGfklvee 30 gd +k++++Y++ L+ e FUN_000342-T1 274 GDFPKAIEYYEKSLNIAREEG 294 799***********9877665 PP == domain 7 score: 0.1 bits; conditional E-value: 3.5 Glyoxalase 10 gdleksldFYtevLGf 25 +d ++++++Y++ L+ FUN_000342-T1 314 RDFPRAIECYEKSLNI 329 6999********9985 PP >> Glyco_hydro_36C Glycosyl hydrolase family 36 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 3.9 1.7e+03 53 69 .. 99 115 .. 94 121 .. 0.87 2 ? 2.1 0.0 0.95 4.1e+02 51 70 .. 137 156 .. 123 160 .. 0.86 3 ? 6.2 0.0 0.048 20 50 71 .. 216 237 .. 182 240 .. 0.87 4 ? -0.4 0.0 5.6 2.4e+03 52 70 .. 298 316 .. 281 320 .. 0.83 5 ? 4.0 0.0 0.24 1e+02 52 71 .. 338 357 .. 322 359 .. 0.89 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 3.9 Glyco_hydro_36C 53 sGdeLmnaGLnlplegd 69 +Gd++ n G+ ++++g FUN_000342-T1 99 QGDAYLNLGIAYKSQGG 115 69*********998875 PP == domain 2 score: 2.1 bits; conditional E-value: 0.95 Glyco_hydro_36C 51 vysGdeLmnaGLnlplegdf 70 Gd++ n G+ ++++ df FUN_000342-T1 137 AREGDAYFNLGIAYKSHSDF 156 568************99998 PP == domain 3 score: 6.2 bits; conditional E-value: 0.048 Glyco_hydro_36C 50 evysGdeLmnaGLnlplegdfq 71 + Gd++ n G+ ++++gdf+ FUN_000342-T1 216 QAREGDAYLNLGIAYKSQGDFT 237 5668****************96 PP == domain 4 score: -0.4 bits; conditional E-value: 5.6 Glyco_hydro_36C 52 ysGdeLmnaGLnlplegdf 70 G ++ n G+ ++++ df FUN_000342-T1 298 REGTAYFNLGIAYKSHRDF 316 579999*******999998 PP == domain 5 score: 4.0 bits; conditional E-value: 0.24 Glyco_hydro_36C 52 ysGdeLmnaGLnlplegdfq 71 G+++ n G+ l+++ dfq FUN_000342-T1 338 REGKTYLNLGIALKSHSDFQ 357 579***************98 PP >> CoV_NSP8 Coronavirus replicase NSP8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.73 3.1e+02 32 52 .. 40 60 .. 22 64 .. 0.81 2 ? 0.3 0.0 1.9 8.1e+02 31 50 .. 79 98 .. 67 106 .. 0.77 3 ? 0.6 0.0 1.5 6.3e+02 26 47 .. 111 132 .. 101 140 .. 0.79 4 ? 1.3 0.0 0.88 3.7e+02 27 52 .. 151 177 .. 141 182 .. 0.79 5 ? -1.7 0.0 7.2 3.1e+03 32 46 .. 197 211 .. 184 221 .. 0.78 6 ? 0.7 0.0 1.4 5.8e+02 29 52 .. 234 257 .. 219 261 .. 0.79 7 ? 5.7 0.0 0.041 18 24 52 .. 268 297 .. 260 304 .. 0.81 8 ? 0.2 0.0 1.9 8.2e+02 31 52 .. 316 337 .. 300 345 .. 0.77 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.73 CoV_NSP8 32 eqllkqlkkalniaksefdrd 52 ++ + ++k+lnia+ + dr FUN_000342-T1 40 PKAIDYYEKSLNIARKVGDRA 60 788999*********998885 PP == domain 2 score: 0.3 bits; conditional E-value: 1.9 CoV_NSP8 31 seqllkqlkkalniaksefd 50 ++ ++ ++k+lnia+ + d FUN_000342-T1 79 FPKAIECYEKSLNIARDAGD 98 3789999********97765 PP == domain 3 score: 0.6 bits; conditional E-value: 1.5 CoV_NSP8 26 kangsseqllkqlkkalniaks 47 k +g+ ++ ++ +kk+lnia FUN_000342-T1 111 KSQGGFPKAIECYKKSLNIAIE 132 445667999**********965 PP == domain 4 score: 1.3 bits; conditional E-value: 0.88 CoV_NSP8 27 angss.eqllkqlkkalniaksefdrd 52 ++ s ++ ++ ++k+lnia + dr FUN_000342-T1 151 KSHSDfPKAIECYEKSLNIASEAGDRA 177 444444899***********9888875 PP == domain 5 score: -1.7 bits; conditional E-value: 7.2 CoV_NSP8 32 eqllkqlkkalniak 46 ++ ++ ++k+lnia FUN_000342-T1 197 PKAIECYEKSLNIAM 211 788999*******95 PP == domain 6 score: 0.7 bits; conditional E-value: 1.4 CoV_NSP8 29 gsseqllkqlkkalniaksefdrd 52 g+ + + ++k+lnia+ + dr FUN_000342-T1 234 GDFTKASECYEKSLNIAREASDRA 257 5556667789********999996 PP == domain 7 score: 5.7 bits; conditional E-value: 0.041 CoV_NSP8 24 ea.kangsseqllkqlkkalniaksefdrd 52 a k +g+ ++ ++ ++k+lnia+ e dr FUN_000342-T1 268 SAhKSQGDFPKAIEYYEKSLNIAREEGDRA 297 452455677****************99996 PP == domain 8 score: 0.2 bits; conditional E-value: 1.9 CoV_NSP8 31 seqllkqlkkalniaksefdrd 52 ++ ++ ++k+lnia + dr FUN_000342-T1 316 FPRAIECYEKSLNIAWEAGDRA 337 4889999********9888886 PP >> TPR_EMC2 EMC2 TPR-like repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 3.3 1.4e+03 67 111 .. 38 88 .. 32 99 .. 0.67 2 ? 3.2 0.0 0.31 1.3e+02 63 111 .. 111 165 .. 98 208 .. 0.74 3 ? 2.1 0.0 0.66 2.8e+02 67 111 .. 195 245 .. 186 257 .. 0.66 4 ? 1.0 0.0 1.5 6.2e+02 63 91 .. 231 259 .. 223 268 .. 0.79 5 ! 8.1 0.0 0.0093 4 62 111 .. 270 325 .. 266 333 .. 0.70 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 3.3 TPR_EMC2 67 dmalaveylnkylelfm......adhdawrelaetyvalqmykqaafcyee 111 d+ a++y +k l++ ++ + + +l ++y ++ + +a cye+ FUN_000342-T1 38 DLPKAIDYYEKSLNIARkvgdraTEGNIYFNLGNAYDSISDFPKAIECYEK 88 666677777777776531111112345677888999999999999999986 PP == domain 2 score: 3.2 bits; conditional E-value: 0.31 TPR_EMC2 63 kaqgdmalaveylnkylelfmadh......dawrelaetyvalqmykqaafcyee 111 k+qg + a+e +k l++ + da+ +l +y + + +a cye+ FUN_000342-T1 111 KSQGGFPKAIECYKKSLNIAIEAGdqaregDAYFNLGIAYKSHSDFPKAIECYEK 165 8899999999999999998876540011115555566666666667777778876 PP == domain 3 score: 2.1 bits; conditional E-value: 0.66 TPR_EMC2 67 dmalaveylnkylelfm.adh.....dawrelaetyvalqmykqaafcyee 111 d+ a+e +k l++ m a h da+ +l +y + + +a+ cye+ FUN_000342-T1 195 DFPKAIECYEKSLNIAMeAGHqaregDAYLNLGIAYKSQGDFTKASECYEK 245 555677777777777663333222226677777777777777788888876 PP == domain 4 score: 1.0 bits; conditional E-value: 1.5 TPR_EMC2 63 kaqgdmalaveylnkylelfmadhdawre 91 k+qgd++ a e +k l++ d re FUN_000342-T1 231 KSQGDFTKASECYEKSLNIAREASDRARE 259 89999999999999999988777777766 PP == domain 5 score: 8.1 bits; conditional E-value: 0.0093 TPR_EMC2 62 akaqgdmalaveylnkylelfmadhdawre......laetyvalqmykqaafcyee 111 k+qgd+ a+ey +k l++ + d re l +y + + + +a cye+ FUN_000342-T1 270 HKSQGDFPKAIEYYEKSLNIAREEGDRAREgtayfnLGIAYKSHRDFPRAIECYEK 325 599*****************999999887711111133444444455566667765 PP >> TPR_Slam Surface lipoprotein assembly modifier, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 6.9 2.9e+03 58 75 .. 34 51 .. 27 56 .. 0.78 2 ? 2.1 0.0 0.83 3.5e+02 54 75 .. 107 128 .. 97 133 .. 0.88 3 ? 1.3 0.0 1.5 6.4e+02 53 77 .. 146 170 .. 142 174 .. 0.83 4 ? 1.8 0.1 1 4.3e+02 54 77 .. 227 250 .. 222 258 .. 0.85 5 ? 5.4 0.0 0.076 32 55 75 .. 268 288 .. 262 298 .. 0.84 6 ? 1.6 0.0 1.2 5.2e+02 52 75 .. 305 328 .. 296 333 .. 0.86 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 6.9 TPR_Slam 58 rsqgnyaeAialYrella 75 +s ++ +Ai++Y++ l+ FUN_000342-T1 34 HSLSDLPKAIDYYEKSLN 51 56678899*****99876 PP == domain 2 score: 2.1 bits; conditional E-value: 0.83 TPR_Slam 54 AilarsqgnyaeAialYrella 75 +i +sqg + +Ai+ Y++ l+ FUN_000342-T1 107 GIAYKSQGGFPKAIECYKKSLN 128 78899*************9876 PP == domain 3 score: 1.3 bits; conditional E-value: 1.5 TPR_Slam 53 qAilarsqgnyaeAialYrellaek 77 +i +s+ ++ +Ai+ Y++ l+ FUN_000342-T1 146 LGIAYKSHSDFPKAIECYEKSLNIA 170 57889999***********998765 PP == domain 4 score: 1.8 bits; conditional E-value: 1 TPR_Slam 54 AilarsqgnyaeAialYrellaek 77 +i +sqg++++A + Y++ l+ FUN_000342-T1 227 GIAYKSQGDFTKASECYEKSLNIA 250 78899*************998765 PP == domain 5 score: 5.4 bits; conditional E-value: 0.076 TPR_Slam 55 ilarsqgnyaeAialYrella 75 +sqg++ +Ai++Y++ l+ FUN_000342-T1 268 SAHKSQGDFPKAIEYYEKSLN 288 56799************9886 PP == domain 6 score: 1.6 bits; conditional E-value: 1.2 TPR_Slam 52 aqAilarsqgnyaeAialYrella 75 +i +s++++ +Ai+ Y++ l+ FUN_000342-T1 305 NLGIAYKSHRDFPRAIECYEKSLN 328 5688999************99876 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.036 15 24 54 .. 32 62 .. 24 81 .. 0.75 2 ? 1.7 0.0 0.92 3.9e+02 24 45 .. 72 93 .. 67 114 .. 0.76 3 ? -0.1 0.0 3.4 1.5e+03 26 43 .. 151 168 .. 123 198 .. 0.73 4 ? 1.1 0.0 1.5 6.2e+02 24 41 .. 189 206 .. 184 238 .. 0.85 5 ? 0.5 0.0 2.2 9.4e+02 21 47 .. 265 292 .. 243 316 .. 0.58 6 ? 3.3 0.0 0.3 1.3e+02 26 71 .. 311 359 .. 305 362 .. 0.77 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.036 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss 54 + hs ++l +A++ Ye+ + +kv ++ + FUN_000342-T1 32 AYHSLSDLPKAIDYYEKSLNIARKVGDRATE 62 579*************999988888887644 PP == domain 2 score: 1.7 bits; conditional E-value: 0.92 WH_Halo_primase 24 efhsarelydAleaYeperewe 45 + s+++ +A+e Ye+ + FUN_000342-T1 72 AYDSISDFPKAIECYEKSLNIA 93 567999*********9876655 PP == domain 3 score: -0.1 bits; conditional E-value: 3.4 WH_Halo_primase 26 hsarelydAleaYepere 43 s ++ +A+e Ye+ + FUN_000342-T1 151 KSHSDFPKAIECYEKSLN 168 566788899999987655 PP == domain 4 score: 1.1 bits; conditional E-value: 1.5 WH_Halo_primase 24 efhsarelydAleaYepe 41 + s+++ +A+e Ye+ FUN_000342-T1 189 AYDSISDFPKAIECYEKS 206 567999999******975 PP == domain 5 score: 0.5 bits; conditional E-value: 2.2 WH_Halo_primase 21 qlgefhsar.elydAleaYepereweqk 47 +lg h + + +A+e Ye+ + ++ FUN_000342-T1 265 NLGSAHKSQgDFPKAIEYYEKSLNIARE 292 5666664443888999999987665444 PP == domain 6 score: 3.3 bits; conditional E-value: 0.3 WH_Halo_primase 26 hsarelydAleaYepere..weqkvknei.ssprsLgnvLkkardhrsv 71 s r+ +A+e Ye+ + we + ++ +Lg Lk+++d +++ FUN_000342-T1 311 KSHRDFPRAIECYEKSLNiaWEAGDRAREgKTYLNLGIALKSHSDFQKL 359 56789999******99887788754444348888999999999887776 PP >> AimR AimR transcriptional regulator-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.34 1.5e+02 170 199 .. 25 55 .. 3 64 .. 0.80 2 ! 7.6 0.1 0.0062 2.7 146 203 .. 38 99 .. 24 110 .. 0.73 3 ? 3.1 0.0 0.14 59 152 200 .. 121 173 .. 112 182 .. 0.75 4 ! 6.9 0.5 0.0098 4.2 148 203 .. 160 216 .. 150 232 .. 0.80 5 ? 3.3 0.5 0.13 54 147 200 .. 236 293 .. 222 311 .. 0.66 6 ? 1.6 0.1 0.4 1.7e+02 183 201 .. 276 294 .. 269 345 .. 0.59 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.34 AimR 170 shltlGnSYl.fesYekamkyfekalkiakn 199 + ++lG+ Y ++ ka+ y+ek+l+ia++ FUN_000342-T1 25 ACFNLGTAYHsLSDLPKAIDYYEKSLNIARK 55 5688999995489**************9985 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0062 AimR 146 eleearkyakkviensn...nprfkalshltlGnSY.lfesYekamkyfekalkiakneekk 203 +l +a y++k ++ ++ + +++lGn Y ++++ ka++ +ek+l+ia+++ ++ FUN_000342-T1 38 DLPKAIDYYEKSLNIARkvgDRATEGNIYFNLGNAYdSISDFPKAIECYEKSLNIARDAGDQ 99 5555666666666665511134445569********779*****************987655 PP == domain 3 score: 3.1 bits; conditional E-value: 0.14 AimR 152 kyakkviensnnprfkal...shltlGnSYl.fesYekamkyfekalkiakne 200 +++kk ++ +++ +a ++++lG Y +++ ka++ +ek+l+ia ++ FUN_000342-T1 121 ECYKKSLNIAIEAGDQARegdAYFNLGIAYKsHSDFPKAIECYEKSLNIASEA 173 5555555555555555555559********75899*************99864 PP == domain 4 score: 6.9 bits; conditional E-value: 0.0098 AimR 148 eearkyakkviensnnprfkalshltlGnSY.lfesYekamkyfekalkiakneekk 203 +e+ + + ++ ++ ++ +++++lGn Y ++++ ka++ +ek+l+ia ++ ++ FUN_000342-T1 160 IECYEKSLNIASEAGDRATEGNVYFNLGNAYdSISDFPKAIECYEKSLNIAMEAGHQ 216 4555566666666667777888*********77*****************9876554 PP == domain 5 score: 3.3 bits; conditional E-value: 0.13 AimR 147 leearkyakkviensnnprfkal...shltlGnSYlfe.sYekamkyfekalkiakne 200 +a+++++k ++ ++ a ++++lG ++ ka++y+ek+l+ia++e FUN_000342-T1 236 FTKASECYEKSLNIAREASDRARegdAYFNLGSAHKSQgDFPKAIEYYEKSLNIAREE 293 4556666666555555444444333477777777765437888888888888888765 PP == domain 6 score: 1.6 bits; conditional E-value: 0.4 AimR 183 Yekamkyfekalkiaknee 201 + ka++y+ek+l+ia++e FUN_000342-T1 276 FPKAIEYYEKSLNIAREEG 294 4555555555555555432 PP >> TPR_5 Tetratrico peptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 7.7 3.3e+03 2 29 .. 24 51 .. 23 55 .. 0.87 2 ? 2.8 0.0 0.44 1.9e+02 2 29 .. 64 91 .. 63 110 .. 0.85 3 ? 4.5 0.0 0.13 54 3 37 .. 182 217 .. 180 258 .. 0.75 4 ? 3.4 0.0 0.28 1.2e+02 3 34 .. 262 293 .. 260 307 .. 0.82 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 7.7 TPR_5 2 vaaferagarDsvGhedkavplYrraLa 29 a f+ ++a s + ka++ Y+++L+ FUN_000342-T1 24 RACFNLGTAYHSLSDLPKAIDYYEKSLN 51 57899999999999999******99986 PP == domain 2 score: 2.8 bits; conditional E-value: 0.44 TPR_5 2 vaaferagarDsvGhedkavplYrraLa 29 + f+ + a Ds+ + ka++ Y+++L+ FUN_000342-T1 64 NIYFNLGNAYDSISDFPKAIECYEKSLN 91 57899999*****************997 PP == domain 3 score: 4.5 bits; conditional E-value: 0.13 TPR_5 3 aaferagarDsvGhedkavplYrraLaaGLa.garr 37 + f+ + a Ds+ + ka++ Y+++L+ ++ g ++ FUN_000342-T1 182 VYFNLGNAYDSISDFPKAIECYEKSLNIAMEaGHQA 217 67999999****************998766423333 PP == domain 4 score: 3.4 bits; conditional E-value: 0.28 TPR_5 3 aaferagarDsvGhedkavplYrraLaaGLag 34 a f+ ++a+ s G+ ka++ Y+++L+ ++ FUN_000342-T1 262 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREE 293 789999*******************9865544 PP >> DUF6845 Domain of unknown function (DUF6845) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.077 33 8 26 .. 40 58 .. 34 66 .. 0.81 2 ? 1.9 0.0 0.75 3.2e+02 8 30 .. 80 102 .. 74 132 .. 0.79 3 ? -1.7 0.0 10 4.2e+03 99 121 .. 148 170 .. 135 179 .. 0.58 4 ? -0.3 0.1 3.6 1.5e+03 99 125 .. 228 254 .. 215 259 .. 0.78 5 ? 3.0 0.0 0.35 1.5e+02 9 23 .. 278 292 .. 272 300 .. 0.86 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.077 DUF6845 8 nevieYYntslevlkdvvn 26 + i+YY++sl++ ++v + FUN_000342-T1 40 PKAIDYYEKSLNIARKVGD 58 678************9966 PP == domain 2 score: 1.9 bits; conditional E-value: 0.75 DUF6845 8 nevieYYntslevlkdvvnekdv 30 + ie Y++sl++ +d +++d+ FUN_000342-T1 80 PKAIECYEKSLNIARDAGDQGDA 102 578999**********9999886 PP == domain 3 score: -1.7 bits; conditional E-value: 10 DUF6845 99 laYlkdddyakakqlleenkkls 121 +aY+ d ka + e++ +++ FUN_000342-T1 148 IAYKSHSDFPKAIECYEKSLNIA 170 55555555555555544444444 PP == domain 4 score: -0.3 bits; conditional E-value: 3.6 DUF6845 99 laYlkdddyakakqlleenkklseels 125 +aY+ + d +ka++ e++ +++ e s FUN_000342-T1 228 IAYKSQGDFTKASECYEKSLNIAREAS 254 689999999999999998888887765 PP == domain 5 score: 3.0 bits; conditional E-value: 0.35 DUF6845 9 evieYYntslevlkd 23 + ieYY++sl++ ++ FUN_000342-T1 278 KAIEYYEKSLNIARE 292 679*********987 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.27 1.1e+02 111 174 .. 35 96 .. 20 129 .. 0.59 2 ? 6.4 0.0 0.017 7.4 101 216 .. 142 253 .. 132 259 .. 0.68 3 ! 7.2 0.0 0.0098 4.2 96 173 .. 217 292 .. 203 330 .. 0.86 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.27 TPR_NPHP3 111 dlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 l+ l +a+ +++L+i + D ++ + +L + y+ f +a + y+++l+i ++a FUN_000342-T1 35 SLSDLPKAIDYYEKSLNIARKV--GDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNIARDA 96 4444555555555555554444..4555556666666677777777777777777777666554 PP == domain 2 score: 6.4 bits; conditional E-value: 0.017 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelea...lally 193 y lG k + +a++ +++L+i a D ++ + +L + y+ f +a + y+++l+i +a G h+ a+e +a l + y FUN_000342-T1 142 AYFNLGIAYKSHSDFPKAIECYEKSLNIASEA--GDRATEGNVYFNLGNAYDSISDFPKAIECYEKSLNIAMEA-G--HQ--AREGDAylnLGIAY 230 56666666666666677777777777776665..6777777888888888888888888888888888887655.3..33..33333322277778 PP TPR_NPHP3 194 qkqdkhdlaeplkkravairkka 216 + q + a + +++++i ++a FUN_000342-T1 231 KSQGDFTKASECYEKSLNIAREA 253 88888888888888888887664 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0098 TPR_NPHP3 96 akvadlyealGrflkdlgllsqalpaLqraLei.RetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 a+ d y lG k g ++a + +++L+i Re++ D + ++ +L + + g f +a ++y+++l+i ++ FUN_000342-T1 217 AREGDAYLNLGIAYKSQGDFTKASECYEKSLNIaREAS---DRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 292 455788999999999999999**********9945554...889999***************************99865 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.072 30 220 245 .. 28 53 .. 12 58 .. 0.85 2 ? 0.4 0.0 1.2 5.1e+02 136 177 .. 131 171 .. 118 188 .. 0.71 3 ? 2.6 0.1 0.25 1.1e+02 132 176 .. 206 250 .. 164 264 .. 0.66 4 ? 4.2 0.1 0.082 35 96 175 .. 206 289 .. 190 306 .. 0.57 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.072 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqn 245 +++A+ l++ +kA y++k ++ + FUN_000342-T1 28 NLGTAYHSLSDLPKAIDYYEKSLNIA 53 589******************87765 PP == domain 2 score: 0.4 bits; conditional E-value: 1.2 TPR_15 136 aeeeealkkseafwllraelerqegekkaAleayreAltlaP 177 +e+ ++++ a++ l +++ + +++ +A+e+y++ l +a FUN_000342-T1 131 IEAGDQAREGDAYFNLGIAY-KSHSDFPKAIECYEKSLNIAS 171 45556677667777766655.567888899*****9998765 PP == domain 3 score: 2.6 bits; conditional E-value: 0.25 TPR_15 132 llasaee.eealkkseafwllraelerqegekkaAleayreAltla 176 +l+ a+e +++++ a++ l ++++ +g+ +A e+y++ l +a FUN_000342-T1 206 SLNIAMEaGHQAREGDAYLNLGIAYK-SQGDFTKASECYEKSLNIA 250 44444442667777788887777665.5699999999999999875 PP == domain 4 score: 4.2 bits; conditional E-value: 0.082 TPR_15 96 aarlalaawqrfrsprfllsalellealkdwkqlasllas....aee.eealkkseafwllraelerqegekkaAleayreAltl 175 ++++a++a ++ r+ + +l+ +++ ++d+++ + ++ a e +++ a++ ++ +++ +g+ +A+e y++ l + FUN_000342-T1 206 SLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKslniAREaSDRAREGDAYFN-LGSAHKSQGDFPKAIEYYEKSLNI 289 555555555566666655555555555655555555554433222221222333333333.344555666666666666666655 PP >> RE_NgoFVII_C NgoFVII C-terminal B3-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.55 2.3e+02 26 58 .. 90 119 .. 78 124 .. 0.78 2 ? -1.2 0.0 5.5 2.4e+03 23 57 .. 124 158 .. 119 168 .. 0.74 3 ? -1.6 0.0 7.1 3e+03 23 56 .. 165 197 .. 148 203 .. 0.76 4 ? 0.6 0.0 1.5 6.6e+02 22 55 .. 204 236 .. 188 241 .. 0.71 5 ? 5.5 0.0 0.045 19 18 58 .. 240 279 .. 235 284 .. 0.84 6 ? -1.2 0.0 5.6 2.4e+03 25 56 .. 286 317 .. 278 325 .. 0.77 7 ? -1.3 0.0 5.7 2.4e+03 24 55 .. 326 356 .. 316 362 .. 0.65 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.55 RE_NgoFVII_C 26 lNvgqareqrkaprdaYirvpkeitrsefypek 58 lN++ ++daY++++ + +++++p+ FUN_000342-T1 90 LNIARDA---GDQGDAYLNLGIAYKSQGGFPKA 119 6666544...3467****************985 PP == domain 2 score: -1.2 bits; conditional E-value: 5.5 RE_NgoFVII_C 23 kSglNvgqareqrkaprdaYirvpkeitrsefype 57 k lN++ + ++ +++daY +++ + ++ +p+ FUN_000342-T1 124 KKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPK 158 45688866665566689999988887777777765 PP == domain 3 score: -1.6 bits; conditional E-value: 7.1 RE_NgoFVII_C 23 kSglNvgqareqrkaprdaYirvpkeitrsefyp 56 kS lN++ + +r ++++ Y +++++ + +p FUN_000342-T1 165 KS-LNIASEAGDRATEGNVYFNLGNAYDSISDFP 197 44.8998888888899999999888766666665 PP == domain 4 score: 0.6 bits; conditional E-value: 1.5 RE_NgoFVII_C 22 ekSglNvgqareqrkaprdaYirvpkeitrsefy 55 ekS lN++ + ++ +++daY++++ + +++ + FUN_000342-T1 204 EKS-LNIAMEAGHQAREGDAYLNLGIAYKSQGDF 236 444.88866554444689****999888777655 PP == domain 5 score: 5.5 bits; conditional E-value: 0.045 RE_NgoFVII_C 18 geveekSglNvgqareqrkaprdaYirvpkeitrsefypek 58 +e ekS lN++ + ++r +++daY +++++ +++ +p+ FUN_000342-T1 240 SECYEKS-LNIAREASDRAREGDAYFNLGSAHKSQGDFPKA 279 4555665.9***9999**99*************99999975 PP == domain 6 score: -1.2 bits; conditional E-value: 5.6 RE_NgoFVII_C 25 glNvgqareqrkaprdaYirvpkeitrsefyp 56 lN++ + +r +++ aY +++ + ++ +p FUN_000342-T1 286 SLNIAREEGDRAREGTAYFNLGIAYKSHRDFP 317 49999999889899999988887766666666 PP == domain 7 score: -1.3 bits; conditional E-value: 5.7 RE_NgoFVII_C 24 SglNvgqareqrkaprdaYirvpkeitrsefy 55 S lN++ + +r ++++ Y++++ + ++ + FUN_000342-T1 326 S-LNIAWEAGDRAREGKTYLNLGIALKSHSDF 356 4.555554555556689999998877766555 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 7.5 3.2e+03 72 103 .. 2 33 .. 1 57 [. 0.72 2 ? -1.1 0.0 5.8 2.5e+03 74 104 .. 44 74 .. 35 96 .. 0.72 3 ? -1.1 0.0 5.8 2.5e+03 65 113 .. 75 120 .. 72 133 .. 0.69 4 ? 0.7 0.0 1.6 6.9e+02 65 104 .. 152 191 .. 151 196 .. 0.86 5 ? 6.2 0.1 0.033 14 64 113 .. 191 240 .. 191 253 .. 0.86 6 ? 4.8 0.1 0.089 38 68 115 .. 235 282 .. 232 293 .. 0.88 7 ? 0.5 0.0 1.9 8.1e+02 65 94 .. 312 341 .. 304 357 .. 0.82 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 7.5 Ulvan_lyase_2nd 72 teelyelalnlakrkgyteleekaealLkqay 103 t e ye l++a+ +g ++ + +a +L ay FUN_000342-T1 2 TIECYEKSLDIAREEGDRARQGRACFNLGTAY 33 56778888888888888877777776666666 PP == domain 2 score: -1.1 bits; conditional E-value: 5.8 Ulvan_lyase_2nd 74 elyelalnlakrkgyteleekaealLkqayd 104 + ye ln+a++ g ++ e + +L +ayd FUN_000342-T1 44 DYYEKSLNIARKVGDRATEGNIYFNLGNAYD 74 5677888888887777777777777766665 PP == domain 3 score: -1.1 bits; conditional E-value: 5.8 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 s ++ + e ye ln+a+ g + +a +L ay+++Gg+ +ai FUN_000342-T1 75 SISDFPKAIECYEKSLNIARDAGDQ---GDAYLNLGIAYKSQGGFPKAI 120 5556667778888888888877653...456666667777777776665 PP == domain 4 score: 0.7 bits; conditional E-value: 1.6 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqayd 104 sh ++ + e ye ln+a+ g ++ e ++ +L +ayd FUN_000342-T1 152 SHSDFPKAIECYEKSLNIASEAGDRATEGNVYFNLGNAYD 191 788899999************9999998888888877775 PP == domain 5 score: 6.2 bits; conditional E-value: 0.033 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Ds ++ + e ye ln+a g ++ e +a +L ay+++G++ +a FUN_000342-T1 191 DSISDFPKAIECYEKSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKAS 240 566677788899*********************************99775 PP == domain 6 score: 4.8 bits; conditional E-value: 0.089 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpaikt 115 ++++ e ye ln+a+ + ++ e +a +L +a +++G++ +ai++ FUN_000342-T1 235 DFTKASECYEKSLNIAREASDRAREGDAYFNLGSAHKSQGDFPKAIEY 282 6788999**********************************9999865 PP == domain 7 score: 0.5 bits; conditional E-value: 1.9 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleek 94 shr++ e ye ln+a g ++ e k FUN_000342-T1 312 SHRDFPRAIECYEKSLNIAWEAGDRAREGK 341 89****************988877766655 PP >> NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 6.7 2.9e+03 24 37 .. 79 92 .. 47 109 .. 0.66 2 ? 5.7 0.0 0.058 25 21 62 .. 113 154 .. 86 161 .. 0.82 3 ? -0.2 0.1 4 1.7e+03 24 41 .. 156 173 .. 152 180 .. 0.84 4 ? 2.3 0.0 0.66 2.8e+02 23 58 .. 195 230 .. 189 239 .. 0.86 5 ? 1.6 0.2 1.1 4.7e+02 10 46 .. 215 251 .. 203 298 .. 0.66 6 ? 2.0 0.0 0.87 3.7e+02 24 66 .. 316 358 .. 305 362 .. 0.88 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 6.7 NRBF2_MIT 24 yeeaischkkaaay 37 + +ai c++k+ ++ FUN_000342-T1 79 FPKAIECYEKSLNI 92 44555555555444 PP == domain 2 score: 5.7 bits; conditional E-value: 0.058 NRBF2_MIT 21 aGkyeeaischkkaaaylseamkltkseqahlslelqreshi 62 G + +ai c+kk+ ++ ea ++ a + l + +sh FUN_000342-T1 113 QGGFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHS 154 57899****************999999999999999999986 PP == domain 3 score: -0.2 bits; conditional E-value: 4 NRBF2_MIT 24 yeeaischkkaaaylsea 41 + +ai c++k+ ++ sea FUN_000342-T1 156 FPKAIECYEKSLNIASEA 173 7789******99999987 PP == domain 4 score: 2.3 bits; conditional E-value: 0.66 NRBF2_MIT 23 kyeeaischkkaaaylseamkltkseqahlslelqr 58 + +ai c++k+ ++ ea + ++ a l l + FUN_000342-T1 195 DFPKAIECYEKSLNIAMEAGHQAREGDAYLNLGIAY 230 5789***********99*999999999999987765 PP == domain 5 score: 1.6 bits; conditional E-value: 1.1 NRBF2_MIT 10 qqsrradrllaaGkyeeaischkkaaaylseamkltk 46 q+r d l G ++ +ka+++ +++++++ FUN_000342-T1 215 HQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAR 251 4666666666666555555555566665555554443 PP == domain 6 score: 2.0 bits; conditional E-value: 0.87 NRBF2_MIT 24 yeeaischkkaaaylseamkltkseqahlslelqreshikqll 66 + ai c++k+ ++ ea ++ ++ l l + +sh ++ FUN_000342-T1 316 FPRAIECYEKSLNIAWEAGDRAREGKTYLNLGIALKSHSDFQK 358 6789**************9999999999999999999987665 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 1.1 4.6e+02 132 159 .. 66 93 .. 24 99 .. 0.71 2 ? 2.0 0.1 0.53 2.2e+02 115 156 .. 83 127 .. 66 137 .. 0.60 3 ? 4.8 0.3 0.074 31 98 161 .. 103 172 .. 93 209 .. 0.66 4 ? 6.8 0.7 0.018 7.6 97 159 .. 222 290 .. 217 297 .. 0.65 5 ? 1.9 0.0 0.58 2.5e+02 130 158 .. 301 329 .. 295 343 .. 0.81 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 1.1 ARM_TT21_C 132 yellGliaekeqsykdAaenYekAWkls 159 y lG +++ + + +A+e+Yek+ +++ FUN_000342-T1 66 YFNLGNAYDSISDFPKAIECYEKSLNIA 93 4458999999999999999999987665 PP == domain 2 score: 2.0 bits; conditional E-value: 0.53 ARM_TT21_C 115 eeLlkkvlkynksc...akAyellGliaekeqsykdAaenYekAW 156 e +k l+ ++ + Ay lG+ + ++ + +A+e+Y+k+ FUN_000342-T1 83 IECYEKSLNIARDAgdqGDAYLNLGIAYKSQGGFPKAIECYKKSL 127 444444444444331113577777777777778888888887765 PP == domain 3 score: 4.8 bits; conditional E-value: 0.074 ARM_TT21_C 98 wLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsykdAaenYekAWklske 161 +L l y ++g + +A e kk l+ + + Ay lG+ + +++ + +A+e+Yek+ ++++e FUN_000342-T1 103 YLNLGIAYKSQGGFPKAIECYKKSLNIAIEAgdqareGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASE 172 5555555555555555555555555544333111111357888999999999999999999998887655 PP == domain 4 score: 6.8 bits; conditional E-value: 0.018 ARM_TT21_C 97 awLlladiyiqsgkldlAeeLlkkvlkynksca.k.....AyellGliaekeqsykdAaenYekAWkls 159 a+L l y ++g + +A+e +k l+ ++ + + Ay lG + ++ + +A+e+Yek+ +++ FUN_000342-T1 222 AYLNLGIAYKSQGDFTKASECYEKSLNIAREASdRaregdAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 290 566666677777777777777777777776654221222255567888888888888888888776665 PP == domain 5 score: 1.9 bits; conditional E-value: 0.58 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWkl 158 Ay lG+ + ++ + A+e+Yek+ ++ FUN_000342-T1 301 TAYFNLGIAYKSHRDFPRAIECYEKSLNI 329 588889******************96444 PP >> DUF627 Protein of unknown function (DUF627) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 3.8 1.6e+03 81 106 .. 27 52 .. 2 57 .. 0.49 2 ? 1.7 0.0 0.8 3.4e+02 78 106 .. 64 92 .. 14 94 .. 0.73 3 ? 1.2 0.0 1.1 4.8e+02 62 106 .. 119 169 .. 116 171 .. 0.81 4 ? 4.9 0.0 0.081 34 62 106 .. 159 209 .. 156 211 .. 0.90 5 ? 0.3 0.0 2.1 9e+02 80 106 .. 263 289 .. 234 291 .. 0.65 6 ? 0.4 0.0 2 8.6e+02 8 28 .. 273 293 .. 266 361 .. 0.68 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.8 DUF627 81 felasqlgsvlyYkkavkkakqaLsv 106 f+l+ + s ++ ka+ +++L + FUN_000342-T1 27 FNLGTAYHSLSDLPKAIDYYEKSLNI 52 44444444444444444444444433 PP == domain 2 score: 1.7 bits; conditional E-value: 0.8 DUF627 78 rsLfelasqlgsvlyYkkavkkakqaLsv 106 + f+l++ ++s +++ ka++ +++L + FUN_000342-T1 64 NIYFNLGNAYDSISDFPKAIECYEKSLNI 92 45578888888888888888877777765 PP == domain 3 score: 1.2 bits; conditional E-value: 1.1 DUF627 62 svecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsv 106 ++ec++++ ++ + f+l+ ++s +++ ka++ +++L + FUN_000342-T1 119 AIECYKKSLNIAieagdqAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNI 169 788888888888888877667778899999999999999999988888876 PP == domain 4 score: 4.9 bits; conditional E-value: 0.081 DUF627 62 svecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsv 106 ++ec++++ ++ + + f+l++ ++s +++ ka++ +++L + FUN_000342-T1 159 AIECYEKSLNIAseagdrATEGNVYFNLGNAYDSISDFPKAIECYEKSLNI 209 899999999999999998899999******************999988876 PP == domain 5 score: 0.3 bits; conditional E-value: 2.1 DUF627 80 LfelasqlgsvlyYkkavkkakqaLsv 106 f+l+s +s+ ++ ka++ +++L + FUN_000342-T1 263 YFNLGSAHKSQGDFPKAIEYYEKSLNI 289 567777777777777777777777765 PP == domain 6 score: 0.4 bits; conditional E-value: 2 DUF627 8 rgnhikALeiiedlisrhked 28 +g+ kA+e e+++ +e+ FUN_000342-T1 273 QGDFPKAIEYYEKSLNIAREE 293 566666666666666554443 PP >> BAG6 BCL2-associated athanogene 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.1 43 57 68 .. 28 39 .. 19 49 .. 0.86 2 ? 2.9 0.0 0.31 1.3e+02 53 68 .. 64 79 .. 42 90 .. 0.79 3 ? 2.3 0.0 0.47 2e+02 53 68 .. 181 196 .. 169 205 .. 0.85 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.1 BAG6 57 llshalhalSDl 68 +l+ a+h+lSDl FUN_000342-T1 28 NLGTAYHSLSDL 39 79*********9 PP == domain 2 score: 2.9 bits; conditional E-value: 0.31 BAG6 53 EalhllshalhalSDl 68 +++ +l++a+ ++SD FUN_000342-T1 64 NIYFNLGNAYDSISDF 79 48899**********7 PP == domain 3 score: 2.3 bits; conditional E-value: 0.47 BAG6 53 EalhllshalhalSDl 68 +++ +l++a+ ++SD FUN_000342-T1 181 NVYFNLGNAYDSISDF 196 57889**********7 PP >> Foie-gras_1 Foie gras liver health family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 0.075 32 164 219 .. 37 92 .. 20 97 .. 0.86 2 ? 4.4 0.0 0.083 35 160 214 .. 150 204 .. 124 215 .. 0.83 3 ? 0.1 0.0 1.8 7.5e+02 170 223 .. 240 293 .. 206 295 .. 0.61 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.075 Foie-gras_1 164 dhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplals 219 + +id ++++l ++k + + ++ ++ ++++++y + d+ ka+e ++ ++ FUN_000342-T1 37 SDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNI 92 5666789***********99999999**********************99876555 PP == domain 2 score: 4.4 bits; conditional E-value: 0.083 Foie-gras_1 160 ekgvdhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellr 214 +k+ + +i++++++l +s+ + + ++ ++ ++++++y + d+ ka+e ++ FUN_000342-T1 150 YKSHSDFPKAIECYEKSLNIASEAGDRATEGNVYFNLGNAYDSISDFPKAIECYE 204 5566666679************999999999********************9987 PP == domain 3 score: 0.1 bits; conditional E-value: 1.8 Foie-gras_1 170 idlLkraleeFskrkqtRlae.elsleiAeEylrlgdwakalellrplalsyrqe 223 ++++++l ++ ++R +e ++++ ++ gd+ ka+e ++ ++ r+e FUN_000342-T1 240 SECYEKSLNIAR-EASDRAREgDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAREE 293 455555555444.333444440344577778888888888887777666666655 PP >> SPO22 Meiosis protein SPO22/ZIP4 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 2 8.4e+02 36 66 .. 24 54 .. 7 91 .. 0.77 2 ? -0.6 0.0 2.3 9.9e+02 11 66 .. 119 171 .. 111 195 .. 0.68 3 ? 7.8 0.0 0.0066 2.8 5 66 .. 233 291 .. 229 308 .. 0.75 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 2 SPO22 36 rllYnigksllskkkyeeavkWLqraldile 66 r ++n g + +s ++ +a+++ +++l i FUN_000342-T1 24 RACFNLGTAYHSLSDLPKAIDYYEKSLNIAR 54 5677777777777777777777777776665 PP == domain 2 score: -0.6 bits; conditional E-value: 2.3 SPO22 11 AehmlskaaednllsldpetaeeLarllYnigksllskkkyeeavkWLqraldile 66 A +++k ++ ++++ + + + ++n g++ s +++ +a+ +++l i + FUN_000342-T1 119 AIECYKK---SLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIAS 171 5555666...2445555666666778888888888888888888866666666655 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0066 SPO22 5 qgdldlAehmlskaaednllsldpetaeeLarllYnigksllskkkyeeavkWLqraldile 66 qgd++ A+ +++k + n+ + +++ + + ++n g + s++++ +a+ + +++l i FUN_000342-T1 233 QGDFTKASECYEK-S-LNIARE-ASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAR 291 7888888888888.2.344444.778888888888888888888888888888888888876 PP >> DUF6178 Family of unknown function (DUF6178) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.95 4.1e+02 306 335 .. 93 122 .. 88 126 .. 0.82 2 ? -1.7 0.0 2.4 1e+03 310 336 .. 137 163 .. 133 166 .. 0.86 3 ? 4.4 0.0 0.034 15 310 337 .. 217 244 .. 210 247 .. 0.87 4 ? -0.4 0.0 0.97 4.1e+02 310 336 .. 297 323 .. 291 326 .. 0.88 5 ? -2.8 0.0 5 2.1e+03 310 332 .. 337 359 .. 335 361 .. 0.83 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.95 DUF6178 306 lrevvekvagylnLGLelLsggdleraael 335 r++ ++ +ylnLG+ + s+g +a e+ FUN_000342-T1 93 ARDAGDQGDAYLNLGIAYKSQGGFPKAIEC 122 688999999*********999988888776 PP == domain 2 score: -1.7 bits; conditional E-value: 2.4 DUF6178 310 vekvagylnLGLelLsggdleraaell 336 +++ +y nLG+ + s++d +a e+ FUN_000342-T1 137 AREGDAYFNLGIAYKSHSDFPKAIECY 163 677889***************999875 PP == domain 3 score: 4.4 bits; conditional E-value: 0.034 DUF6178 310 vekvagylnLGLelLsggdleraaelle 337 +++ +ylnLG+ + s+gd +a+e+ e FUN_000342-T1 217 AREGDAYLNLGIAYKSQGDFTKASECYE 244 678889*****************99866 PP == domain 4 score: -0.4 bits; conditional E-value: 0.97 DUF6178 310 vekvagylnLGLelLsggdleraaell 336 +++ ++y nLG+ + s+ d ra e+ FUN_000342-T1 297 AREGTAYFNLGIAYKSHRDFPRAIECY 323 68999****************999875 PP == domain 5 score: -2.8 bits; conditional E-value: 5 DUF6178 310 vekvagylnLGLelLsggdlera 332 +++ ylnLG+ l s++d ++ FUN_000342-T1 337 AREGKTYLNLGIALKSHSDFQKL 359 567788*******9999998875 PP >> DUF5385 Family of unknown function (DUF5385) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.18 75 123 150 .. 65 92 .. 45 100 .. 0.86 2 ? 3.6 0.0 0.14 61 123 154 .. 182 213 .. 175 223 .. 0.83 3 ? -1.2 0.0 4.2 1.8e+03 124 150 .. 303 329 .. 276 342 .. 0.74 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.18 DUF5385 123 vlFvtkdaktsvidepriieaevktvkv 150 ++F +a s+ d p++ie+ k +++ FUN_000342-T1 65 IYFNLGNAYDSISDFPKAIECYEKSLNI 92 9********************8777665 PP == domain 2 score: 3.6 bits; conditional E-value: 0.14 DUF5385 123 vlFvtkdaktsvidepriieaevktvkvkskk 154 v+F +a s+ d p++ie+ k +++ + FUN_000342-T1 182 VYFNLGNAYDSISDFPKAIECYEKSLNIAMEA 213 89*******************88887776554 PP == domain 3 score: -1.2 bits; conditional E-value: 4.2 DUF5385 124 lFvtkdaktsvidepriieaevktvkv 150 +F a s d pr+ie+ k +++ FUN_000342-T1 303 YFNLGIAYKSHRDFPRAIECYEKSLNI 329 66666777788899*****97776665 PP >> PT26-6P_helical PT26-6P, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.1 0.043 18 66 106 .. 41 79 .. 34 91 .. 0.86 2 ? 0.5 0.1 2.1 9e+02 85 108 .. 81 104 .. 72 115 .. 0.67 3 ? 1.9 0.3 0.81 3.4e+02 39 100 .. 87 150 .. 81 158 .. 0.49 4 ? 2.0 0.2 0.73 3.1e+02 65 106 .. 157 196 .. 119 197 .. 0.75 5 ? 5.6 0.8 0.058 25 37 108 .. 162 238 .. 158 255 .. 0.63 6 ? 1.2 0.1 1.3 5.5e+02 66 79 .. 278 291 .. 267 319 .. 0.71 7 ? -1.2 0.0 7.3 3.1e+03 66 106 .. 318 356 .. 306 360 .. 0.75 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.043 PT26-6P_helical 66 kaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 kai++y+++++ rk+ d + e ++++ ++ i df FUN_000342-T1 41 KAIDYYEKSLNIARKVG--DRATEGNIYFNLGNAYDSISDF 79 9*************995..6677888899999999999998 PP == domain 2 score: 0.5 bits; conditional E-value: 2.1 PT26-6P_helical 85 davdeillalkvakkleqiGdfym 108 +a++ + + l++a++ Gd y+ FUN_000342-T1 81 KAIECYEKSLNIARDAGDQGDAYL 104 455556666666666666666664 PP == domain 3 score: 1.9 bits; conditional E-value: 0.81 PT26-6P_helical 39 eekitaaedlkkkadaegne....kakllaekaieayddaiealrkieqtdavdeillalkvakkl 100 e+ + a d ++ da n k++ kaie y+++++ ie d++ e ++++ + FUN_000342-T1 87 EKSLNIARDAGDQGDAYLNLgiayKSQGGFPKAIECYKKSLNI--AIEAGDQAREGDAYFNLGIAY 150 4444555555555555444311112222334777777777653..455556655555555555555 PP == domain 4 score: 2.0 bits; conditional E-value: 0.73 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 kaie y+++++ e d + e ++++ ++ i df FUN_000342-T1 157 PKAIECYEKSLNIAS--EAGDRATEGNVYFNLGNAYDSISDF 196 478888888876543..5667788888888888888888887 PP == domain 5 score: 5.6 bits; conditional E-value: 0.058 PT26-6P_helical 37 sleekitaaedlkkkadaegnekakl.lae.......kaieayddaiealrkieqtdavdeillalkvakkleqiGdfym 108 e+ + a + ++a+ egn +l a kaie y+++++ +e +++ e +l++ + Gdf FUN_000342-T1 162 CYEKSLNIASEAGDRAT-EGNVYFNLgNAYdsisdfpKAIECYEKSLNI--AMEAGHQAREGDAYLNLGIAYKSQGDFTK 238 55666666777777776.6664333212220011122777777777664..45677778888888999999999999964 PP == domain 6 score: 1.2 bits; conditional E-value: 1.3 PT26-6P_helical 66 kaieayddaiealr 79 kaie+y+++++ r FUN_000342-T1 278 KAIEYYEKSLNIAR 291 9*******998655 PP == domain 7 score: -1.2 bits; conditional E-value: 7.3 PT26-6P_helical 66 kaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 +aie y+++++ e d + e + +l++ l df FUN_000342-T1 318 RAIECYEKSLNI--AWEAGDRAREGKTYLNLGIALKSHSDF 356 688999998765..356777788888888887777776666 PP >> DHR-2_Lobe_A DHR-2, Lobe A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 3.4 1.4e+03 127 148 .. 148 169 .. 141 175 .. 0.82 2 ? 5.4 0.1 0.07 30 99 149 .. 200 250 .. 190 255 .. 0.80 3 ? 1.2 0.0 1.4 5.8e+02 127 145 .. 308 326 .. 300 332 .. 0.85 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 3.4 DHR-2_Lobe_A 127 piyekkrdYkklseihkklael 148 y+++ d+ k e+++k ++ FUN_000342-T1 148 IAYKSHSDFPKAIECYEKSLNI 169 579*************997665 PP == domain 2 score: 5.4 bits; conditional E-value: 0.07 DHR-2_Lobe_A 99 velleeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaely 149 +e +e+ ++ +a + + y l y+++ d++k se+++k ++ FUN_000342-T1 200 IECYEKSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIA 250 666777777777777777777788888899**************9987765 PP == domain 3 score: 1.2 bits; conditional E-value: 1.4 DHR-2_Lobe_A 127 piyekkrdYkklseihkkl 145 y+++rd+ + e+++k FUN_000342-T1 308 IAYKSHRDFPRAIECYEKS 326 67**************986 PP >> NSF Aromatic-di-Alanine (AdAR) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 6.2 2.7e+03 2 7 .. 3 8 .. 2 12 .. 0.83 2 ? 2.0 0.1 2.3 9.8e+02 1 10 [. 42 51 .. 42 53 .. 0.81 3 ? 3.5 0.1 0.71 3e+02 1 10 [. 82 91 .. 82 93 .. 0.81 4 ? 1.0 0.1 4.7 2e+03 1 7 [. 119 125 .. 118 130 .. 0.73 5 ? 3.5 0.1 0.71 3e+02 1 10 [. 159 168 .. 159 170 .. 0.81 6 ? 3.5 0.1 0.71 3e+02 1 10 [. 199 208 .. 199 210 .. 0.81 7 ? 2.5 0.0 1.5 6.3e+02 7 12 .] 238 243 .. 236 249 .. 0.63 8 ? 1.6 0.2 3 1.3e+03 1 10 [. 279 288 .. 279 290 .. 0.80 9 ? 3.5 0.1 0.71 3e+02 1 10 [. 319 328 .. 319 330 .. 0.81 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 6.2 NSF 2 akhyek 7 +++yek FUN_000342-T1 3 IECYEK 8 89***8 PP == domain 2 score: 2.0 bits; conditional E-value: 2.3 NSF 1 AakhyekAae 10 A+++yek + FUN_000342-T1 42 AIDYYEKSLN 51 99****9755 PP == domain 3 score: 3.5 bits; conditional E-value: 0.71 NSF 1 AakhyekAae 10 A+++yek + FUN_000342-T1 82 AIECYEKSLN 91 99****9755 PP == domain 4 score: 1.0 bits; conditional E-value: 4.7 NSF 1 Aakhyek 7 A+++y k FUN_000342-T1 119 AIECYKK 125 7888877 PP == domain 5 score: 3.5 bits; conditional E-value: 0.71 NSF 1 AakhyekAae 10 A+++yek + FUN_000342-T1 159 AIECYEKSLN 168 99****9755 PP == domain 6 score: 3.5 bits; conditional E-value: 0.71 NSF 1 AakhyekAae 10 A+++yek + FUN_000342-T1 199 AIECYEKSLN 208 99****9755 PP == domain 7 score: 2.5 bits; conditional E-value: 1.5 NSF 7 kAaeiy 12 kA+e+y FUN_000342-T1 238 KASECY 243 555555 PP == domain 8 score: 1.6 bits; conditional E-value: 3 NSF 1 AakhyekAae 10 A+++yek + FUN_000342-T1 279 AIEYYEKSLN 288 89****9655 PP == domain 9 score: 3.5 bits; conditional E-value: 0.71 NSF 1 AakhyekAae 10 A+++yek + FUN_000342-T1 319 AIECYEKSLN 328 99****9755 PP >> Cdc6_lid Cdc6 AAA+ ATPase-type lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 5.9 2.5e+03 35 56 .. 38 59 .. 35 64 .. 0.83 2 ? -1.7 0.0 9.3 4e+03 38 55 .. 118 135 .. 107 142 .. 0.55 3 ? 0.2 0.0 2.4 1e+03 29 57 .. 149 177 .. 147 183 .. 0.79 4 ? -0.6 0.0 4.2 1.8e+03 28 56 .. 228 256 .. 226 262 .. 0.79 5 ? 5.2 0.0 0.065 28 29 56 .. 269 296 .. 267 299 .. 0.91 6 ? -1.7 0.0 9.1 3.9e+03 39 52 .. 326 339 .. 309 342 .. 0.71 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 5.9 Cdc6_lid 35 DaRrAldlLrkAgelAeregse 56 D+ +A+d +k+ ++A++ g++ FUN_000342-T1 38 DLPKAIDYYEKSLNIARKVGDR 59 5568999999999999998876 PP == domain 2 score: -1.7 bits; conditional E-value: 9.3 Cdc6_lid 38 rAldlLrkAgelAeregs 55 +A++ +k+ ++A + g+ FUN_000342-T1 118 KAIECYKKSLNIAIEAGD 135 566665555555555444 PP == domain 3 score: 0.2 bits; conditional E-value: 2.4 Cdc6_lid 29 aaqesGDaRrAldlLrkAgelAeregser 57 a +++ D +A++ +k+ ++A + g++ FUN_000342-T1 149 AYKSHSDFPKAIECYEKSLNIASEAGDRA 177 56677788899999999999999988764 PP == domain 4 score: -0.6 bits; conditional E-value: 4.2 Cdc6_lid 28 laaqesGDaRrAldlLrkAgelAeregse 56 +a +++GD +A + +k+ ++A++ ++ FUN_000342-T1 228 IAYKSQGDFTKASECYEKSLNIAREASDR 256 56788999999999999999999877654 PP == domain 5 score: 5.2 bits; conditional E-value: 0.065 Cdc6_lid 29 aaqesGDaRrAldlLrkAgelAeregse 56 a +++GD +A++ +k+ ++A++eg++ FUN_000342-T1 269 AHKSQGDFPKAIEYYEKSLNIAREEGDR 296 56789********************986 PP == domain 6 score: -1.7 bits; conditional E-value: 9.1 Cdc6_lid 39 AldlLrkAgelAer 52 +l++ ++Ag+ A++ FUN_000342-T1 326 SLNIAWEAGDRARE 339 45666777777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (364 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 400 (0.0156586); expected 510.9 (0.02) Passed bias filter: 355 (0.013897); expected 510.9 (0.02) Passed Vit filter: 87 (0.00340575); expected 25.5 (0.001) Passed Fwd filter: 61 (0.00238794); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 60 [number of targets reported over threshold] # CPU time: 0.47u 0.40s 00:00:00.87 Elapsed: 00:00:00.46 # Mc/sec: 3222.13 // Query: FUN_000343-T1 [L=400] Description: FUN_000343 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-92 303.0 4.0 7.5e-18 65.0 0.2 6.0 6 TPR_12 Tetratricopeptide repeat 1.5e-80 262.5 19.5 7.2e-09 35.6 0.2 9.1 9 TPR_1 Tetratricopeptide repeat 4.6e-66 214.0 11.8 9.8e-07 28.9 0.1 9.2 9 TPR_2 Tetratricopeptide repeat 6.9e-65 210.1 1.2 5.9e-07 29.6 0.0 9.1 9 TPR_7 Tetratricopeptide repeat 1.3e-56 184.4 18.8 1.8e-06 28.1 0.1 9.2 9 TPR_8 Tetratricopeptide repeat 1.6e-40 136.4 0.0 8.6e-05 22.9 0.0 9.2 9 TPR_10 Tetratricopeptide repeat 4.3e-28 96.5 0.0 0.021 16.0 0.0 9.3 9 TPR_6 Tetratricopeptide repeat 2e-26 93.6 11.1 2.4e-09 37.6 0.9 3.1 3 SNAP Soluble NSF attachment protein, SNAP 6.8e-25 85.7 0.4 0.11 13.4 0.1 10.6 9 TPR_17 Tetratricopeptide repeat 8.1e-25 87.4 0.0 2.5e-05 25.1 0.1 7.7 7 TPR_16 Tetratricopeptide repeat 4.8e-23 81.1 41.3 0.0049 17.0 0.0 14.7 14 TPR_11 TPR repeat 1.9e-17 62.5 0.0 0.49 11.7 0.0 9.0 9 TPR_14 Tetratricopeptide repeat 8.9e-16 58.2 0.0 0.034 14.6 0.0 6.5 8 TPR_9 Tetratricopeptide repeat 1.7e-15 57.6 0.0 3e-06 27.2 0.0 3.3 3 TPR_MalT MalT-like TPR region 1.2e-14 55.0 0.1 5.4 7.8 0.0 8.8 9 DUF7018 Domain of unknown function (DUF7018) 1e-12 48.4 1.0 0.019 15.5 0.0 5.7 5 ANAPC5 Anaphase-promoting complex subunit 5 1.4e-12 48.0 12.5 1.1 9.9 0.0 9.0 9 MIT MIT (microtubule interacting and transp 8.2e-12 45.7 12.2 8 7.7 0.1 10.4 9 Sel1 Sel1 repeat 1.4e-11 44.9 7.8 0.19 11.9 0.2 7.4 7 RPN7 26S proteasome subunit RPN7 2.6e-11 43.3 9.2 0.034 13.3 0.2 5.8 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.6e-09 38.3 8.4 6.2 7.1 0.1 8.2 8 DUF7380 Domain of unknown function (DUF7380) 2.8e-09 37.6 2.0 0.36 11.7 0.0 5.5 7 TPR_19 Tetratricopeptide repeat 3.7e-09 37.1 0.0 0.35 11.2 0.0 6.5 5 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H 6.2e-09 36.8 6.5 15 6.3 0.0 8.4 10 ARM_TT21_4th Tetratricopeptide repeat protein 21 for 1.6e-08 35.0 3.2 10 6.2 0.0 7.5 6 ComR_TPR ComR tetratricopeptide 3.7e-08 33.2 7.0 30 4.7 0.0 8.8 9 SHNi-TPR SHNi-TPR 5.4e-08 33.3 0.1 0.79 10.3 0.0 6.1 6 Rapsyn_N Rapsyn N-terminal myristoylation and li 7.1e-08 32.8 6.8 20 5.6 0.1 7.8 8 TPR_BSK1_C Serine/threonine-protein kinase BSK1-li 2.4e-07 31.5 7.3 1.3 9.9 0.0 5.7 8 ANAPC3 Anaphase-promoting complex, cyclosome, 1.4e-06 29.1 0.1 1.1e+02 3.6 0.0 7.6 8 DUF7971 Family of unknown function (DUF7971) 2.5e-06 27.8 12.5 2.8 8.4 0.1 7.2 7 ssDBP Phage single-stranded DNA-binding prote 5.3e-06 27.3 0.1 93 3.9 0.0 7.5 8 Glyoxalase Glyoxalase/Bleomycin resistance protein 7.2e-06 26.3 1.2 39 4.5 0.0 7.3 9 Clathrin Region in Clathrin and VPS 7.4e-06 26.2 5.1 2.8 7.9 0.1 6.1 7 DUF6377 Domain of unknown function (DUF6377) 1.9e-05 25.5 1.3 0.99 10.3 0.0 5.8 5 TPR_IF140_C IF140 C-terminal TPR domain 2.2e-05 24.9 10.7 2.7 8.3 0.0 6.4 7 ARM_TT21_C Tetratricopeptide repeat protein 21 C-t 3e-05 24.3 0.0 4.8 7.3 0.0 4.9 5 TPR_COPA_B COPA/B TPR domain 4.2e-05 24.4 4.0 36 5.3 0.0 7.0 7 TPR_Slam Surface lipoprotein assembly modifier, 5e-05 22.3 0.3 0.27 10.0 0.0 3.8 3 Cohesin_load Cohesin loading factor 7.6e-05 23.4 0.3 2.1 9.0 0.0 4.1 5 TPR_EMC2 EMC2 TPR-like repeat domain 0.00016 21.7 0.0 4.1 7.2 0.0 3.9 5 TPR_NPHP3 Nephrocystin-3 TPR domain 0.00035 21.3 0.6 55 4.5 0.0 5.4 5 TPR_5 Tetratrico peptide repeat 0.00045 19.9 10.1 3.1 7.3 0.1 5.5 7 AimR AimR transcriptional regulator-like 0.00097 19.2 2.1 0.5 10.3 0.1 3.3 4 RNPP_C RNPP family C-terminal domain 0.0016 19.4 0.2 26 5.9 0.0 4.7 4 Glyco_hydro_36C Glycosyl hydrolase family 36 C-terminal 0.0022 18.9 0.0 62 5.1 0.0 5.4 4 TPR_4 Tetratricopeptide repeat 0.0026 18.2 5.1 21 5.5 0.0 6.9 9 CoV_NSP8 Coronavirus replicase NSP8 0.0047 17.6 0.2 37 5.0 0.0 5.2 4 DUF6845 Domain of unknown function (DUF6845) 0.0057 17.3 3.4 19 6.0 0.0 5.6 7 WH_Halo_primase Halobacteria primase winged helix domai 0.0061 17.1 2.3 19 5.8 0.1 5.1 5 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain ------ inclusion threshold ------ 0.011 15.7 0.8 3.3 7.6 0.0 3.5 3 SPO22 Meiosis protein SPO22/ZIP4 like 0.013 15.4 0.4 31 4.3 0.0 4.3 3 TPR_15 Tetratricopeptide repeat 0.026 14.7 0.0 2.4 8.3 0.0 2.3 2 T5_p143 Bacteriophage T5 tail completion protei 0.038 14.1 0.0 31 4.6 0.0 3.3 3 Foie-gras_1 Foie gras liver health family 1 0.048 14.0 4.8 31 5.0 0.0 5.9 6 Cdc6_lid Cdc6 AAA+ ATPase-type lid domain 0.056 12.4 0.0 16 4.2 0.0 3.2 4 DUF6178 Family of unknown function (DUF6178) 0.076 13.8 3.8 16 6.3 0.0 5.0 5 NRBF2_MIT MIT domain of nuclear receptor-binding 0.14 12.5 0.0 50 4.3 0.0 3.2 3 BAG6 BCL2-associated athanogene 6 0.15 12.5 2.1 43 4.5 0.0 4.8 4 Ferritin Ferritin-like domain 0.15 12.3 0.1 19 5.6 0.0 3.9 5 RE_NgoFVII_C NgoFVII C-terminal B3-like DNA-binding 0.18 12.4 0.2 98 3.5 0.0 4.1 3 ATP-synt_B ATP synthase B/B' CF(0) 0.22 12.5 0.0 81 4.2 0.0 4.0 3 Glyco_tran_10_N Fucosyltransferase, N-terminal 0.26 12.1 5.6 33 5.3 0.1 4.8 4 DHR-2_Lobe_A DHR-2, Lobe A 0.44 11.3 14.3 16 6.2 0.7 5.5 6 PT26-6P_helical PT26-6P, helical domain 0.48 10.5 2.1 39 4.3 0.0 3.2 3 Phage_tail_tube_init Putative phage tail tube initiator prot 0.78 9.9 8.7 0.48 10.6 0.8 4.0 4 DUF6591 Family of unknown function (DUF6591) 0.9 11.0 27.9 3.4e+02 3.3 0.1 9.7 9 NSF Aromatic-di-Alanine (AdAR) repeat Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.1 0.1 9.9e-17 3.8e-14 8 77 .] 51 118 .. 45 118 .. 0.94 2 ! 57.2 0.0 5.4e-18 2.1e-15 8 76 .. 91 157 .. 86 158 .. 0.97 3 ! 58.2 0.0 2.5e-18 9.6e-16 4 76 .. 164 234 .. 161 235 .. 0.95 4 ! 42.8 0.0 1.7e-13 6.3e-11 18 75 .. 218 273 .. 217 275 .. 0.96 5 ! 65.0 0.2 2e-20 7.5e-18 4 77 .] 284 355 .. 281 355 .. 0.96 6 ! 59.2 0.0 1.2e-18 4.8e-16 5 75 .. 325 393 .. 323 393 .. 0.96 Alignments for each domain: == domain 1 score: 53.1 bits; conditional E-value: 9.9e-17 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 l+ ++ + ++++A+e++ek+l++a+++ +d+ + +a +nLg++y+ l d+ +A++++e++l+ia+k FUN_000343-T1 51 SLGIIYDSRSDFQKAIECYEKSLDIAREE--GDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARK 118 699999999*****************999..9999********************************996 PP == domain 2 score: 57.2 bits; conditional E-value: 5.4e-18 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 nl+ +++ l ++ +A++++ek+l++a+++ +d+ + ++++nLg +y d+ +A+e++e++l+ia+ FUN_000343-T1 91 NLGTAYHSLSDLPKAIDYYEKSLNIARKV--GDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNIAR 157 8****************************..99**********************************98 PP == domain 3 score: 58.2 bits; conditional E-value: 2.5e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ ++ +g++ +A+e+++k+l++a ++ +d + a++nLg++y d+ +A+e++e++l+ia FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSLNIAIEA--GDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIAS 234 6899**************************999..8999*******************************985 PP == domain 4 score: 42.8 bits; conditional E-value: 1.7e-13 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 ++ +A+e++ek+l++a+++ +d+ + ++++nLg +y d+ +A+e++e++l+ia FUN_000343-T1 218 DFPKAIECYEKSLNIASEA--GDRATEGNVHFNLGNAYDSISDFPKAIECYEKSLNIA 273 789**************99..99*********************************98 PP == domain 5 score: 65.0 bits; conditional E-value: 2e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++nl+ ++ +g++++A e++ek+l++a+++ d+ + a++nLg ++ +gd+ +A+e++e++l+ia++ FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLNIAREA--SDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 355 5899*****************************..99**********************************986 PP == domain 6 score: 59.2 bits; conditional E-value: 1.2e-18 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ nl++++ +g++ +A+e++ek+l++a+++ +d+ + ta++nLg++y d+ A+e++e++l+ia FUN_000343-T1 325 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREE--GDRAREGTAYFNLGITYKSHRDFPRAIECYEKSLNIA 393 678**************************999..9999******************************996 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 4.9e-08 1.9e-05 6 31 .. 51 76 .. 47 78 .. 0.90 2 ! 28.3 0.1 3.8e-09 1.4e-06 2 31 .. 87 116 .. 86 118 .. 0.92 3 ! 30.4 0.1 8.2e-10 3.1e-07 3 31 .. 128 156 .. 126 158 .. 0.92 4 ! 35.6 0.2 1.9e-11 7.2e-09 2 30 .. 164 192 .. 163 193 .. 0.94 5 ! 30.3 0.1 8.9e-10 3.4e-07 2 30 .. 204 232 .. 203 235 .. 0.93 6 ! 28.6 0.0 3.1e-09 1.2e-06 3 30 .. 245 272 .. 243 273 .. 0.93 7 ! 31.9 0.2 2.8e-10 1.1e-07 2 31 .. 284 313 .. 283 315 .. 0.93 8 ! 33.6 0.1 7.7e-11 3e-08 2 31 .. 324 353 .. 323 355 .. 0.93 9 ! 25.2 0.0 3.7e-08 1.4e-05 3 30 .. 365 392 .. 364 393 .. 0.94 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 4.9e-08 TPR_1 6 nlGnayfklgkydeAleyyekALeln 31 lG +y + ++++A+e+yek L + FUN_000343-T1 51 SLGIIYDSRSDFQKAIECYEKSLDIA 76 79*********************986 PP == domain 2 score: 28.3 bits; conditional E-value: 3.8e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay++l ++ +A++yyek L + FUN_000343-T1 87 RACFNLGTAYHSLSDLPKAIDYYEKSLNIA 116 699***********************9875 PP == domain 3 score: 30.4 bits; conditional E-value: 8.2e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 +++nlGnay + ++ +A+e+yek L + FUN_000343-T1 128 IYFNLGNAYDSISDFPKAIECYEKSLNIA 156 7************************9876 PP == domain 4 score: 35.6 bits; conditional E-value: 1.9e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay ++g++ +A+e+y+k L + FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSLNI 192 79***********************9965 PP == domain 5 score: 30.3 bits; conditional E-value: 8.9e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a++nlG ay + ++ +A+e+yek L + FUN_000343-T1 204 DAYFNLGIAYKSHSDFPKAIECYEKSLNI 232 79************************977 PP == domain 6 score: 28.6 bits; conditional E-value: 3.1e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 +++nlGnay + ++ +A+e+yek L + FUN_000343-T1 245 VHFNLGNAYDSISDFPKAIECYEKSLNI 272 79**********************9965 PP == domain 7 score: 31.9 bits; conditional E-value: 2.8e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay ++g++ +A e+yek L + FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLNIA 313 79************************9775 PP == domain 8 score: 33.6 bits; conditional E-value: 7.7e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG a+ ++g++ +A+eyyek L + FUN_000343-T1 324 DAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 353 79************************9775 PP == domain 9 score: 25.2 bits; conditional E-value: 3.7e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a++nlG +y + ++ A+e+yek L + FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEKSLNI 392 9***********************9965 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 9.4e-06 0.0036 7 32 .. 52 77 .. 47 79 .. 0.90 2 ! 21.5 0.0 6.2e-07 0.00024 2 31 .. 87 116 .. 86 118 .. 0.93 3 ! 22.8 0.0 2.3e-07 8.8e-05 3 33 .. 128 158 .. 126 159 .. 0.93 4 ! 27.3 0.0 8.8e-09 3.4e-06 2 30 .. 164 192 .. 163 195 .. 0.94 5 ! 24.3 0.0 7.6e-08 2.9e-05 2 31 .. 204 233 .. 203 236 .. 0.93 6 ! 22.3 0.0 3.4e-07 0.00013 3 31 .. 245 273 .. 243 276 .. 0.93 7 ! 26.0 0.1 2.3e-08 8.7e-06 2 32 .. 284 314 .. 283 316 .. 0.93 8 ! 28.9 0.1 2.6e-09 9.8e-07 2 31 .. 324 353 .. 323 356 .. 0.93 9 ! 22.2 0.0 3.7e-07 0.00014 3 30 .. 365 392 .. 363 393 .. 0.94 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 9.4e-06 TPR_2 7 lGlayyklgdyeeAleayekAleldP 32 lG +y + d+++A+e+yek+l ++ FUN_000343-T1 52 LGIIYDSRSDFQKAIECYEKSLDIAR 77 9*********************9975 PP == domain 2 score: 21.5 bits; conditional E-value: 6.2e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG ay l d+ +A+++yek+l ++ FUN_000343-T1 87 RACFNLGTAYHSLSDLPKAIDYYEKSLNIA 116 69*************************987 PP == domain 3 score: 22.8 bits; conditional E-value: 2.3e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAleldPn 33 +++nlG+ay d+ +A+e+yek+l ++ + FUN_000343-T1 128 IYFNLGNAYDSISDFPKAIECYEKSLNIARD 158 79************************99865 PP == domain 4 score: 27.3 bits; conditional E-value: 8.8e-09 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ nlG ay +gd+ +A+e+y+k+l + FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSLNI 192 69************************987 PP == domain 5 score: 24.3 bits; conditional E-value: 7.6e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG ay d+ +A+e+yek+l ++ FUN_000343-T1 204 DAYFNLGIAYKSHSDFPKAIECYEKSLNIA 233 69*************************987 PP == domain 6 score: 22.3 bits; conditional E-value: 3.4e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 +++nlG+ay d+ +A+e+yek+l ++ FUN_000343-T1 245 VHFNLGNAYDSISDFPKAIECYEKSLNIA 273 89************************986 PP == domain 7 score: 26.0 bits; conditional E-value: 2.3e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ nlG ay +gd+ +A e+yek+l ++ FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLNIAR 314 69*************************9975 PP == domain 8 score: 28.9 bits; conditional E-value: 2.6e-09 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG a+ +gd+ +A+e+yek+l ++ FUN_000343-T1 324 DAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 353 69*************************987 PP == domain 9 score: 22.2 bits; conditional E-value: 3.7e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a++nlG y d+ +A+e+yek+l + FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEKSLNI 392 9************************987 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 5.1e-08 2e-05 3 36 .] 50 83 .. 48 83 .. 0.94 2 ! 24.4 0.0 7.1e-08 2.7e-05 1 36 [] 88 123 .. 88 123 .. 0.97 3 ! 22.5 0.0 2.8e-07 0.00011 3 35 .. 130 162 .. 128 163 .. 0.94 4 ! 22.6 0.0 2.7e-07 0.0001 1 35 [. 165 199 .. 165 200 .. 0.92 5 ! 16.7 0.0 2.1e-05 0.008 1 36 [] 205 240 .. 205 240 .. 0.95 6 ! 19.7 0.0 2.3e-06 0.00087 2 35 .. 246 279 .. 245 280 .. 0.92 7 ! 23.7 0.1 1.2e-07 4.6e-05 1 36 [] 285 320 .. 285 320 .. 0.95 8 ! 29.6 0.0 1.5e-09 5.9e-07 1 36 [] 325 360 .. 325 360 .. 0.96 9 ! 15.2 0.0 6.1e-05 0.023 1 34 [. 365 398 .. 365 400 .] 0.87 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 5.1e-08 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedre 36 ++L+ iy ++ d+++Ai++ye+ L++a++++dr+ FUN_000343-T1 50 LSLGIIYDSRSDFQKAIECYEKSLDIAREEGDRA 83 68******************************96 PP == domain 2 score: 24.4 bits; conditional E-value: 7.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L+ +y++l d +Ai++ye+ L +a++ +dr+ FUN_000343-T1 88 ACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRA 123 8********************************995 PP == domain 3 score: 22.5 bits; conditional E-value: 2.8e-07 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +L+++y + d+ +Ai++ye+ L +a+d +d+ FUN_000343-T1 130 FNLGNAYDSISDFPKAIECYEKSLNIARDAGDQ 162 79***************************9985 PP == domain 4 score: 22.6 bits; conditional E-value: 2.7e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y ++Gd+ +Ai++y++ L +a + +d+ FUN_000343-T1 165 AYLNLGIAYKSQGDFPKAIECYKKSLNIAIEAGDQ 199 789***********************999888775 PP == domain 5 score: 16.7 bits; conditional E-value: 2.1e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L+ +y + d+ +Ai++ye+ L +a + +dr+ FUN_000343-T1 205 AYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRA 240 789***************************999985 PP == domain 6 score: 19.7 bits; conditional E-value: 2.3e-06 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+++y + d+ +Ai++ye+ L +a++ +++ FUN_000343-T1 246 HFNLGNAYDSISDFPKAIECYEKSLNIAMEAGHQ 279 579************************9998875 PP == domain 7 score: 23.7 bits; conditional E-value: 1.2e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +y ++Gd+ +A ++ye+ L +a++ +dr+ FUN_000343-T1 285 AYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRA 320 789****************************99985 PP == domain 8 score: 29.6 bits; conditional E-value: 1.5e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L++++ ++Gd+ +Ai++ye+ L +a++++dr+ FUN_000343-T1 325 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRA 360 789*******************************96 PP == domain 9 score: 15.2 bits; conditional E-value: 6.1e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+ +L+ +y + +d+ +Ai++ye+ L +a + +d FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEKSLNIAWEAGD 398 789*********************9988755555 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 1.9e-05 0.0072 5 33 .. 50 78 .. 47 79 .. 0.90 2 ! 22.6 0.0 2.9e-07 0.00011 2 33 .. 87 118 .. 86 119 .. 0.95 3 ! 22.1 0.0 4e-07 0.00015 3 33 .. 128 158 .. 126 158 .. 0.94 4 ! 23.1 0.1 2e-07 7.6e-05 2 30 .. 164 192 .. 163 193 .. 0.95 5 ! 17.2 0.1 1.5e-05 0.0056 2 31 .. 204 233 .. 203 235 .. 0.94 6 ! 17.2 0.0 1.5e-05 0.0058 3 30 .. 245 272 .. 243 273 .. 0.93 7 ! 27.3 0.2 8.8e-09 3.3e-06 2 32 .. 284 314 .. 283 315 .. 0.95 8 ! 28.1 0.1 4.7e-09 1.8e-06 2 33 .. 324 355 .. 323 356 .. 0.94 9 ! 15.6 0.0 5e-05 0.019 3 30 .. 365 392 .. 363 393 .. 0.94 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1.9e-05 TPR_8 5 ynlGliylklgdyeeAkeyyekaleldpd 33 + lG iy + d+++A+e+yek+l+++++ FUN_000343-T1 50 LSLGIIYDSRSDFQKAIECYEKSLDIARE 78 56999********************9975 PP == domain 2 score: 22.6 bits; conditional E-value: 2.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldpd 33 +a++nlG +y++l d+ +A+ yyek+l ++++ FUN_000343-T1 87 RACFNLGTAYHSLSDLPKAIDYYEKSLNIARK 118 89**************************9975 PP == domain 3 score: 22.1 bits; conditional E-value: 4e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldpd 33 +y+nlG++y + d+ +A+e+yek+l +++d FUN_000343-T1 128 IYFNLGNAYDSISDFPKAIECYEKSLNIARD 158 8**************************9975 PP == domain 4 score: 23.1 bits; conditional E-value: 2e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay+nlG +y+++gd+ +A+e+y+k+l + FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSLNI 192 69************************987 PP == domain 5 score: 17.2 bits; conditional E-value: 1.5e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay+nlG +y++ d+ +A+e+yek+l ++ FUN_000343-T1 204 DAYFNLGIAYKSHSDFPKAIECYEKSLNIA 233 69*************************997 PP == domain 6 score: 17.2 bits; conditional E-value: 1.5e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 +++nlG++y + d+ +A+e+yek+l + FUN_000343-T1 245 VHFNLGNAYDSISDFPKAIECYEKSLNI 272 689**********************988 PP == domain 7 score: 27.3 bits; conditional E-value: 8.8e-09 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y+++gd+ +A e+yek+l +++ FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLNIAR 314 69*************************9987 PP == domain 8 score: 28.1 bits; conditional E-value: 4.7e-09 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldpd 33 +ay+nlG++++++gd+ +A+eyyek+l ++++ FUN_000343-T1 324 DAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 355 69**************************9975 PP == domain 9 score: 15.6 bits; conditional E-value: 5e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay+nlG +y++ d+ A+e+yek+l + FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEKSLNI 392 9************************988 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 0.0016 0.62 7 34 .. 51 78 .. 48 79 .. 0.94 2 ! 13.8 0.0 0.00016 0.061 7 35 .. 91 119 .. 89 119 .. 0.98 3 ! 10.8 0.0 0.0015 0.57 9 37 .. 126 154 .. 126 158 .. 0.83 4 ! 18.6 0.0 4.9e-06 0.0019 3 34 .. 164 195 .. 163 196 .. 0.92 5 ? 7.3 0.0 0.018 6.9 7 32 .. 208 233 .. 204 236 .. 0.90 6 ! 9.9 0.0 0.0027 1 9 37 .. 243 271 .. 243 280 .. 0.85 7 ! 22.9 0.0 2.3e-07 8.6e-05 3 35 .. 284 316 .. 283 319 .. 0.94 8 ! 18.7 0.0 4.7e-06 0.0018 7 34 .. 328 355 .. 324 356 .. 0.94 9 ! 10.6 0.0 0.0017 0.65 7 31 .. 368 392 .. 364 395 .. 0.91 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0016 TPR_10 7 nLanalraqgryeeAeelleealairer 34 L+ ++ ++ +++ A e +e++l+i+++ FUN_000343-T1 51 SLGIIYDSRSDFQKAIECYEKSLDIARE 78 69***********************987 PP == domain 2 score: 13.8 bits; conditional E-value: 0.00016 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++a+ ++ ++ A +++e++l i+++v FUN_000343-T1 91 NLGTAYHSLSDLPKAIDYYEKSLNIARKV 119 9*************************997 PP == domain 3 score: 10.8 bits; conditional E-value: 0.0015 TPR_10 9 analraqgryeeAeelleealairervlG 37 +n+++++g+ ++ ++ +a++++e+ l+ FUN_000343-T1 126 GNIYFNLGNAYDSISDFPKAIECYEKSLN 154 68899999999999999999999998876 PP == domain 4 score: 18.6 bits; conditional E-value: 4.9e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 +++ nL+ a+ +qg++ A e ++++l i+ + FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSLNIAIE 195 5899***********************99765 PP == domain 5 score: 7.3 bits; conditional E-value: 0.018 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+ a+ + ++ A e +e++l i+ FUN_000343-T1 208 NLGIAYKSHSDFPKAIECYEKSLNIA 233 9*********************9886 PP == domain 6 score: 9.9 bits; conditional E-value: 0.0027 TPR_10 9 analraqgryeeAeelleealairervlG 37 +n+++++g+ ++ ++ +a++++e+ l+ FUN_000343-T1 243 GNVHFNLGNAYDSISDFPKAIECYEKSLN 271 78999999999999999999999999887 PP == domain 7 score: 22.9 bits; conditional E-value: 2.3e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL+ a+ +qg+++ A e +e++l i++++ FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLNIAREA 316 5899**************************997 PP == domain 8 score: 18.7 bits; conditional E-value: 4.7e-06 TPR_10 7 nLanalraqgryeeAeelleealairer 34 nL+ a+ +qg++ A e++e++l i+++ FUN_000343-T1 328 NLGSAHKSQGDFPKAIEYYEKSLNIARE 355 9************************987 PP == domain 9 score: 10.6 bits; conditional E-value: 0.0017 TPR_10 7 nLanalraqgryeeAeelleealai 31 nL+ ++ + +++ +A e +e++l i FUN_000343-T1 368 NLGITYKSHRDFPRAIECYEKSLNI 392 9*********************987 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.096 37 1 25 [. 47 71 .. 47 75 .. 0.91 2 ? 5.4 0.0 0.13 50 4 25 .. 90 111 .. 87 115 .. 0.91 3 ? 5.0 0.0 0.17 64 3 25 .. 129 151 .. 128 156 .. 0.91 4 ! 16.0 0.0 5.4e-05 0.021 1 25 [. 164 188 .. 164 191 .. 0.94 5 ! 9.8 0.0 0.0051 1.9 1 25 [. 204 228 .. 204 232 .. 0.92 6 ? 4.0 0.0 0.34 1.3e+02 4 25 .. 247 268 .. 245 271 .. 0.90 7 ! 14.4 0.0 0.00017 0.066 1 25 [. 284 308 .. 284 312 .. 0.94 8 ! 15.6 0.0 7.3e-05 0.028 1 25 [. 324 348 .. 324 352 .. 0.94 9 ? 7.2 0.0 0.034 13 2 25 .. 365 388 .. 364 392 .. 0.91 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.096 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA l l+ +y d+++A++ +++ FUN_000343-T1 47 DASLSLGIIYDSRSDFQKAIECYEK 71 78899*******99*********98 PP == domain 2 score: 5.4 bits; conditional E-value: 0.13 TPR_6 4 lklalsylelgdkdeAkaalqr 25 ++l+ +y l d +A++++++ FUN_000343-T1 90 FNLGTAYHSLSDLPKAIDYYEK 111 89*******99*********98 PP == domain 3 score: 5.0 bits; conditional E-value: 0.17 TPR_6 3 llklalsylelgdkdeAkaalqr 25 +++l+ +y d+ +A++ +++ FUN_000343-T1 129 YFNLGNAYDSISDFPKAIECYEK 151 699*******88*********98 PP == domain 4 score: 16.0 bits; conditional E-value: 5.4e-05 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +y+ +gd+ +A++ +++ FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKK 188 8**********************97 PP == domain 5 score: 9.8 bits; conditional E-value: 0.0051 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+++l+ +y+ d+ +A++ +++ FUN_000343-T1 204 DAYFNLGIAYKSHSDFPKAIECYEK 228 8***********77*********98 PP == domain 6 score: 4.0 bits; conditional E-value: 0.34 TPR_6 4 lklalsylelgdkdeAkaalqr 25 ++l+ +y d+ +A++ +++ FUN_000343-T1 247 FNLGNAYDSISDFPKAIECYEK 268 89*******88*********98 PP == domain 7 score: 14.4 bits; conditional E-value: 0.00017 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l+ +y+ +gd+++A + +++ FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEK 308 8********************9997 PP == domain 8 score: 15.6 bits; conditional E-value: 7.3e-05 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+++l+ +++ +gd+ +A++++++ FUN_000343-T1 324 DAYFNLGSAHKSQGDFPKAIEYYEK 348 8**********************98 PP == domain 9 score: 7.2 bits; conditional E-value: 0.034 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+++l+ y+ d+ +A++ +++ FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEK 388 99*********88*********98 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.8 0.1 6e-09 2.3e-06 87 180 .. 59 151 .. 54 162 .. 0.94 2 ! 37.6 0.9 6.3e-12 2.4e-09 35 151 .. 163 279 .. 156 289 .. 0.87 3 ! 34.1 1.4 7.3e-11 2.8e-08 36 142 .. 284 390 .. 276 396 .. 0.94 Alignments for each domain: == domain 1 score: 27.8 bits; conditional E-value: 6e-09 SNAP 87 ksdpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 +sd ++A+e++ek+ +i e+g r ++ ++++ y + +dl kAi++Ye++ ++ ++ + a+ +++ ++ + + + +++kAie yek FUN_000343-T1 59 RSDFQKAIECYEKSLDIAREEGDRARQGRACFNLGTAYHSL-SDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEK 151 56889**********************************87.**************************************************97 PP == domain 2 score: 37.6 bits; conditional E-value: 6.3e-12 SNAP 35 adlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelq 129 d y + + ayk + ++ +A e++ k ++ +++++ ++ay++ +yk+ d +A+e++ek+ +i e+g + ++ ++++++ y++ + FUN_000343-T1 163 GDAYLNLGIAYKSQGDFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHsDFPKAIECYEKSLNIASEAGDRATEGNVHFNLGNAYDSI-S 257 5788888999*************************************99999985778*********************************988.* PP SNAP 130 dlekAieaYeqAadlyeqeeae 151 d+ kAie+Ye++ ++ + + + FUN_000343-T1 258 DFPKAIECYEKSLNIAMEAGHQ 279 **********988765555555 PP == domain 3 score: 34.1 bits; conditional E-value: 7.3e-11 SNAP 36 dlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqd 130 d y + + ayk + ++++A+e+++k ++ ++++++ ++ay++ + k++ d +A+e +ek+ +i e+g r ++ +++++ y++ d FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRAREGDAYFNLGSAHKSQgDFPKAIEYYEKSLNIAREEGDRAREGTAYFNLGITYKSH-RD 378 77888899****************************************999987999***********************************9.** PP SNAP 131 lekAieaYeqAa 142 + +Aie+Ye++ FUN_000343-T1 379 FPRAIECYEKSL 390 *********975 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.68 2.6e+02 2 8 .. 62 68 .. 42 76 .. 0.64 2 ? 4.0 0.0 0.27 1e+02 17 33 .. 90 106 .. 87 107 .. 0.93 3 ? 8.3 0.0 0.012 4.4 14 34 .] 127 147 .. 123 147 .. 0.89 4 ! 13.4 0.1 0.00028 0.11 11 34 .] 161 184 .. 148 184 .. 0.78 5 ! 9.6 0.0 0.0045 1.7 14 34 .] 204 224 .. 199 224 .. 0.91 6 ? 6.0 0.0 0.065 25 14 34 .] 244 264 .. 240 264 .. 0.89 7 ! 9.4 0.1 0.0051 1.9 14 32 .. 284 302 .. 280 302 .. 0.92 8 ! 9.4 0.0 0.0052 2 14 34 .] 324 344 .. 321 344 .. 0.93 9 ? 7.6 0.0 0.02 7.5 15 34 .] 365 384 .. 362 384 .. 0.92 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.68 TPR_17 2 ylkalel 8 ++ka+e+ FUN_000343-T1 62 FQKAIEC 68 4555555 PP == domain 2 score: 4.0 bits; conditional E-value: 0.27 TPR_17 17 ynLArlllnnGqleeAl 33 +nL+++++ + +l +A+ FUN_000343-T1 90 FNLGTAYHSLSDLPKAI 106 8*************997 PP == domain 3 score: 8.3 bits; conditional E-value: 0.012 TPR_17 14 dayynLArlllnnGqleeAlq 34 ++y+nL++++ ++ +A++ FUN_000343-T1 127 NIYFNLGNAYDSISDFPKAIE 147 79*************999985 PP == domain 4 score: 13.4 bits; conditional E-value: 0.00028 TPR_17 11 nnadayynLArlllnnGqleeAlq 34 + day nL+++++ +G++ +A++ FUN_000343-T1 161 DQGDAYLNLGIAYKSQGDFPKAIE 184 5689*****************985 PP == domain 5 score: 9.6 bits; conditional E-value: 0.0045 TPR_17 14 dayynLArlllnnGqleeAlq 34 day+nL+++++ ++ +A++ FUN_000343-T1 204 DAYFNLGIAYKSHSDFPKAIE 224 8***************99985 PP == domain 6 score: 6.0 bits; conditional E-value: 0.065 TPR_17 14 dayynLArlllnnGqleeAlq 34 ++++nL++++ ++ +A++ FUN_000343-T1 244 NVHFNLGNAYDSISDFPKAIE 264 789************999985 PP == domain 7 score: 9.4 bits; conditional E-value: 0.0051 TPR_17 14 dayynLArlllnnGqleeA 32 day nL+++++ +G++ +A FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKA 302 8**************9987 PP == domain 8 score: 9.4 bits; conditional E-value: 0.0052 TPR_17 14 dayynLArlllnnGqleeAlq 34 day+nL+ +++ +G++ +A++ FUN_000343-T1 324 DAYFNLGSAHKSQGDFPKAIE 344 8*****************985 PP == domain 9 score: 7.6 bits; conditional E-value: 0.02 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay+nL+++++ ++ +A++ FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIE 384 8************9999985 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.04 15 31 61 .. 46 76 .. 39 80 .. 0.86 2 ! 16.8 0.0 2.5e-05 0.0097 3 58 .. 52 113 .. 50 118 .. 0.89 3 ! 17.4 0.0 1.7e-05 0.0065 2 58 .. 131 190 .. 130 200 .. 0.85 4 ? 8.4 0.0 0.011 4.3 20 58 .. 190 230 .. 187 239 .. 0.84 5 ! 10.9 0.0 0.0018 0.69 2 50 .. 248 302 .. 247 310 .. 0.85 6 ! 25.1 0.1 6.5e-08 2.5e-05 1 58 [. 287 350 .. 287 359 .. 0.86 7 ? 3.4 0.0 0.41 1.6e+02 2 22 .. 368 388 .. 367 391 .. 0.86 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.04 TPR_16 31 aaAllglGlallrqgrlaeAaaayraalraa 61 +A+l lG ++ + ++++A++ y++ l++a FUN_000343-T1 46 GDASLSLGIIYDSRSDFQKAIECYEKSLDIA 76 5899*****************9999988765 PP == domain 2 score: 16.8 bits; conditional E-value: 2.5e-05 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ + + d++ A++++e l+ + +A ++lG a++ + +l++A+++y++ l FUN_000343-T1 52 LGIIYDSRSDFQKAIECYEKSLDIAreegdrARQGRACFNLGTAYHSLSDLPKAIDYYEKSL 113 6777888999********99998888899**99*************************9876 PP == domain 3 score: 17.4 bits; conditional E-value: 1.7e-05 TPR_16 2 alaraalaagdyddAaaaleaalrrn...PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ d++ A++++e l + +A+l+lG a+ qg++++A++ y++ l FUN_000343-T1 131 NLGNAYDSISDFPKAIECYEKSLNIArdaGDQGDAYLNLGIAYKSQGDFPKAIECYKKSL 190 68999999***********887633334899**********************9998876 PP == domain 4 score: 8.4 bits; conditional E-value: 0.011 TPR_16 20 leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l a++++ + +A+++lG a+ ++++A++ y++ l FUN_000343-T1 190 LNIAIEAGdqAREGDAYFNLGIAYKSHSDFPKAIECYEKSL 230 67788888888899********************9998876 PP == domain 5 score: 10.9 bits; conditional E-value: 0.0018 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeA 50 l++a+ d++ A++++e l + +A+l+lG a+ qg++++A FUN_000343-T1 248 NLGNAYDSISDFPKAIECYEKSLNIAmeaghqAREGDAYLNLGIAYKSQGDFTKA 302 68999999999999999999988666668899999*****************999 PP == domain 6 score: 25.1 bits; conditional E-value: 6.5e-08 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l l+ a+ +gd+ A +++e l + +A+++lG a+ qg++++A+++y++ l FUN_000343-T1 287 LNLGIAYKSQGDFTKASECYEKSLNIAreasdrAREGDAYFNLGSAHKSQGDFPKAIEYYEKSL 350 67999**************9876633335779*99*************************9976 PP == domain 7 score: 3.4 bits; conditional E-value: 0.41 TPR_16 2 alaraalaagdyddAaaalea 22 l+ + ++d+++A++++e FUN_000343-T1 368 NLGITYKSHRDFPRAIECYEK 388 678899999**********96 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.0 0.015 5.9 4 23 .. 56 75 .. 53 78 .. 0.84 2 ? 6.7 0.0 0.021 8.1 1 23 [. 93 115 .. 93 118 .. 0.92 3 ? 5.6 0.4 0.049 19 29 38 .. 127 136 .. 125 139 .. 0.93 4 ! 16.6 3.4 1.7e-05 0.0065 1 42 [] 133 177 .. 133 177 .. 0.89 5 ! 17.0 0.0 1.3e-05 0.0049 3 23 .. 172 192 .. 170 193 .. 0.92 6 ? 5.7 0.3 0.044 17 29 39 .. 204 214 .. 203 217 .. 0.90 7 ? 6.5 0.1 0.025 9.4 9 23 .. 218 232 .. 213 236 .. 0.84 8 ? 4.2 0.1 0.13 49 29 38 .. 244 253 .. 243 256 .. 0.92 9 ! 8.8 0.1 0.0048 1.8 1 23 [. 250 272 .. 250 273 .. 0.92 10 ! 7.9 0.3 0.009 3.4 29 42 .] 284 297 .. 283 297 .. 0.95 11 ! 12.5 0.1 0.00034 0.13 3 23 .. 292 312 .. 290 316 .. 0.91 12 ! 10.1 0.3 0.0018 0.7 1 23 [. 330 352 .. 323 355 .. 0.86 13 ? 2.9 0.1 0.32 1.2e+02 29 39 .. 364 374 .. 363 376 .. 0.87 14 ? 3.5 0.0 0.22 85 10 23 .. 379 392 .. 378 393 .. 0.86 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.015 TPR_11 4 yyeqGkyeeAieaYkkAlkl 23 y ++ ++ +Aie+Y+k l++ FUN_000343-T1 56 YDSRSDFQKAIECYEKSLDI 75 5578899*********9987 PP == domain 2 score: 6.7 bits; conditional E-value: 0.021 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G ay+++ ++++Ai Y+k l++ FUN_000343-T1 93 GTAYHSLSDLPKAIDYYEKSLNI 115 779****************9987 PP == domain 3 score: 5.6 bits; conditional E-value: 0.049 TPR_11 29 eayynLGlay 38 ++y+nLG+ay FUN_000343-T1 127 NIYFNLGNAY 136 69*******9 PP == domain 4 score: 16.6 bits; conditional E-value: 1.7e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPd...naeayynLGlayykqG 42 G+ay + ++++Aie+Y+k l++ d + +ay+nLG ay qG FUN_000343-T1 133 GNAYDSISDFPKAIECYEKSLNIARDagdQGDAYLNLGIAYKSQG 177 89999999***************997222578**********998 PP == domain 5 score: 17.0 bits; conditional E-value: 1.3e-05 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +qG++++Aie+Ykk l++ FUN_000343-T1 172 AYKSQGDFPKAIECYKKSLNI 192 89***************9987 PP == domain 6 score: 5.7 bits; conditional E-value: 0.044 TPR_11 29 eayynLGlayy 39 +ay+nLG ay FUN_000343-T1 204 DAYFNLGIAYK 214 79********7 PP == domain 7 score: 6.5 bits; conditional E-value: 0.025 TPR_11 9 kyeeAieaYkkAlkl 23 ++++Aie+Y+k l++ FUN_000343-T1 218 DFPKAIECYEKSLNI 232 789********9998 PP == domain 8 score: 4.2 bits; conditional E-value: 0.13 TPR_11 29 eayynLGlay 38 ++++nLG+ay FUN_000343-T1 244 NVHFNLGNAY 253 68*******9 PP == domain 9 score: 8.8 bits; conditional E-value: 0.0048 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G+ay + ++++Aie+Y+k l++ FUN_000343-T1 250 GNAYDSISDFPKAIECYEKSLNI 272 89999999***********9987 PP == domain 10 score: 7.9 bits; conditional E-value: 0.009 TPR_11 29 eayynLGlayykqG 42 +ay+nLG ay qG FUN_000343-T1 284 DAYLNLGIAYKSQG 297 79*********998 PP == domain 11 score: 12.5 bits; conditional E-value: 0.00034 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay +qG++++A e+Y+k l++ FUN_000343-T1 292 AYKSQGDFTKASECYEKSLNI 312 89***************9987 PP == domain 12 score: 10.1 bits; conditional E-value: 0.0018 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G a +qG++++Aie Y+k l++ FUN_000343-T1 330 GSAHKSQGDFPKAIEYYEKSLNI 352 67888999999999999998887 PP == domain 13 score: 2.9 bits; conditional E-value: 0.32 TPR_11 29 eayynLGlayy 39 +ay+nLG +y FUN_000343-T1 364 TAYFNLGITYK 374 59******996 PP == domain 14 score: 3.5 bits; conditional E-value: 0.22 TPR_11 10 yeeAieaYkkAlkl 23 ++ Aie+Y+k l++ FUN_000343-T1 379 FPRAIECYEKSLNI 392 678*******9987 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.57 2.2e+02 4 31 .. 49 76 .. 47 88 .. 0.79 2 ? 2.2 0.0 1.5 5.9e+02 7 28 .. 92 113 .. 87 121 .. 0.86 3 ? 2.9 0.0 0.9 3.4e+02 3 29 .. 128 154 .. 126 161 .. 0.84 4 ! 10.1 0.0 0.0045 1.7 2 28 .. 164 190 .. 163 197 .. 0.92 5 ? 3.1 0.0 0.8 3e+02 3 28 .. 205 230 .. 203 238 .. 0.87 6 ? 1.8 0.0 2.1 8.2e+02 5 28 .. 247 270 .. 244 277 .. 0.84 7 ! 10.1 0.0 0.0045 1.7 2 29 .. 284 311 .. 283 322 .. 0.87 8 ! 11.7 0.0 0.0013 0.49 2 29 .. 324 351 .. 323 362 .. 0.87 9 ? 3.3 0.0 0.68 2.6e+02 4 30 .. 366 392 .. 364 398 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.57 TPR_14 4 wlalarallalGdpdeAlelleralald 31 l l+ ++ + d+++A+e++e+ l FUN_000343-T1 49 SLSLGIIYDSRSDFQKAIECYEKSLDIA 76 577888899999**********998765 PP == domain 2 score: 2.2 bits; conditional E-value: 1.5 TPR_14 7 larallalGdpdeAlelleral 28 l+ a+ l d+ +A++++e+ l FUN_000343-T1 92 LGTAYHSLSDLPKAIDYYEKSL 113 788999999**********976 PP == domain 3 score: 2.9 bits; conditional E-value: 0.9 TPR_14 3 awlalarallalGdpdeAlellerala 29 ++ l++a+ d+ +A+e++e+ l FUN_000343-T1 128 IYFNLGNAYDSISDFPKAIECYEKSLN 154 5778999999999**********9876 PP == domain 4 score: 10.1 bits; conditional E-value: 0.0045 TPR_14 2 eawlalarallalGdpdeAlelleral 28 +a+l l+ a+ +Gd+ +A+e++++ l FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSL 190 68999******************9866 PP == domain 5 score: 3.1 bits; conditional E-value: 0.8 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+ l+ a+ d+ +A+e++e+ l FUN_000343-T1 205 AYFNLGIAYKSHSDFPKAIECYEKSL 230 78889999***************976 PP == domain 6 score: 1.8 bits; conditional E-value: 2.1 TPR_14 5 lalarallalGdpdeAlelleral 28 l++a+ d+ +A+e++e+ l FUN_000343-T1 247 FNLGNAYDSISDFPKAIECYEKSL 270 56899999999*********9976 PP == domain 7 score: 10.1 bits; conditional E-value: 0.0045 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+l l+ a+ +Gd+ +A e++e+ l FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKSLN 311 68999*******************9876 PP == domain 8 score: 11.7 bits; conditional E-value: 0.0013 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+ l+ a+ +Gd+ +A+e++e+ l FUN_000343-T1 324 DAYFNLGSAHKSQGDFPKAIEYYEKSLN 351 578899******************9876 PP == domain 9 score: 3.3 bits; conditional E-value: 0.68 TPR_14 4 wlalarallalGdpdeAlelleralal 30 + l+ ++ d+ +A+e++e+ l FUN_000343-T1 366 YFNLGITYKSHRDFPRAIECYEKSLNI 392 6678889999************98765 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.0 0.003 1.1 2 59 .. 53 116 .. 52 124 .. 0.82 2 ? 5.0 0.0 0.089 34 4 57 .. 95 147 .. 92 159 .. 0.83 3 ! 10.5 0.0 0.0018 0.67 7 58 .. 138 192 .. 132 203 .. 0.83 4 ! 10.3 0.0 0.002 0.77 3 66 .. 171 240 .. 169 244 .. 0.92 5 ! 8.3 0.0 0.0084 3.2 3 57 .. 211 264 .. 209 281 .. 0.86 6 ! 14.6 0.0 9e-05 0.034 7 66 .. 255 320 .. 249 323 .. 0.90 7 ? 5.2 0.0 0.08 30 31 66 .. 325 360 .. 320 362 .. 0.84 8 ? 3.3 0.0 0.31 1.2e+02 3 23 .. 371 391 .. 369 397 .. 0.83 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.003 TPR_9 2 kaiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylala 59 iy ++ d+++a++++e l + + ++ + ++ G +y+ l +l +A+++ e+ l +a FUN_000343-T1 53 GIIYDSRSDFQKAIECYEKSLDIareegdRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIA 116 5788899999999999999999988888888999999999999999999999999988877655 PP == domain 2 score: 5.0 bits; conditional E-value: 0.089 TPR_9 4 iyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y++ dl++a+ ++e l +a + +++r G +y++lg+ ++ d+ ++++ FUN_000343-T1 95 AYHSLSDLPKAIDYYEKSLNIA-RKVGDRATEGNIYFNLGNAYDSISDFPKAIE 147 6788889999999999999996.8999999999999999999999999877775 PP == domain 3 score: 10.5 bits; conditional E-value: 0.0018 TPR_9 7 reedleralavverllll...aPddpeerrdrGllyaqlgcleaAladLeaylal 58 + d+++a++++e l + a d+ + + + G++y +g++ +A+++ ++ l + FUN_000343-T1 138 SISDFPKAIECYEKSLNIardAGDQGDAYLNLGIAYKSQGDFPKAIECYKKSLNI 192 5579************998877889999*******************99877654 PP == domain 4 score: 10.3 bits; conditional E-value: 0.002 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 +y ++ d+++a++++ l + + ++ + +++ G++y ++ +A+++ e+ l +a +a d++ FUN_000343-T1 171 IAYKSQGDFPKAIECYKKSLNIaieagdQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRA 240 6789999*************999999999999999*************************9999998875 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0084 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 +y + d+++a++++e l +a ++++r G ++++lg+ ++ d+ ++++ FUN_000343-T1 211 IAYKSHSDFPKAIECYEKSLNIAS-EAGDRATEGNVHFNLGNAYDSISDFPKAIE 264 6788999***************97.5899999*********99999999987775 PP == domain 6 score: 14.6 bits; conditional E-value: 9e-05 TPR_9 7 reedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 + d+++a++++e l + + ++ + + + G++y +g++ +A ++ e+ l +a +a d++ FUN_000343-T1 255 SISDFPKAIECYEKSLNIameaghQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRA 320 55799************99999999999999***************************99999986 PP == domain 7 score: 5.2 bits; conditional E-value: 0.08 TPR_9 31 errdrGllyaqlgcleaAladLeaylalapdapdae 66 +++ G+++ +g++ +A+++ e+ l +a + d++ FUN_000343-T1 325 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRA 360 67899999999**********999998888777665 PP == domain 8 score: 3.3 bits; conditional E-value: 0.31 TPR_9 3 aiyireedleralavverlll 23 y + +d++ra++++e l FUN_000343-T1 371 ITYKSHRDFPRAIECYEKSLN 391 678899**********98775 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 1.1e-05 0.0044 10 114 .. 55 160 .. 46 164 .. 0.91 2 ! 13.5 0.0 0.00012 0.045 40 155 .. 163 276 .. 158 287 .. 0.85 3 ! 27.2 0.0 7.9e-09 3e-06 15 116 .. 257 359 .. 243 393 .. 0.91 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.1e-05 TPR_MalT 10 lavsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyq 104 ++ s+ ++++a+e ++ L++ +e+ ar + a ++lG+a++ + dl +A + +++ +ar+ ++ + +++ + ++ +A+e y+ FUN_000343-T1 55 IYDSRSDFQKAIECYEKSLDIAREEGDRARqGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYE 150 5667899***************999888888*******************************999999877888889999999999********** PP TPR_MalT 105 qalqlaqesk 114 + l a++++ FUN_000343-T1 151 KSLNIARDAG 160 ****999876 PP == domain 2 score: 13.5 bits; conditional E-value: 0.00012 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 + a+l+lG a+ qgd+ +A + +++ +a +a++ + a+ ++ + ++ +A+e y++ l a e++ +a+ g ++ l++ + FUN_000343-T1 163 GDAYLNLGIAYKSQGDFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRAT--EGNVHFNLGNAYDSI 256 67899*************************99999999989999999999999999******************99975..556666889999999 PP TPR_MalT 136 ndLeeAeqhlqqgiqlgrql 155 d+ +A ++ +++++++ ++ FUN_000343-T1 257 SDFPKAIECYEKSLNIAMEA 276 99999999999988888776 PP == domain 3 score: 27.2 bits; conditional E-value: 7.9e-09 TPR_MalT 15 geaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 ++++a+e ++ L++ e + ar + a+l+lG a+ qgd+++A + +++ +ar+a + + a+ ++ + qG++ +A+e y++ l FUN_000343-T1 257 SDFPKAIECYEKSLNIAMEAGHQAReGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNI 352 5799999999**************************************************99999999**************************** PP TPR_MalT 110 aqeskle 116 a+e++ + FUN_000343-T1 353 AREEGDR 359 *998766 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.082 31 67 88 .. 57 78 .. 55 87 .. 0.86 2 ? 6.1 0.0 0.047 18 70 92 .. 100 122 .. 94 130 .. 0.84 3 ? 4.1 0.0 0.2 76 69 93 .. 139 163 .. 133 172 .. 0.83 4 ? 4.4 0.0 0.16 61 68 89 .. 175 196 .. 170 207 .. 0.85 5 ? 4.0 0.0 0.2 76 69 92 .. 216 239 .. 211 248 .. 0.84 6 ? 3.0 0.0 0.42 1.6e+02 69 89 .. 256 276 .. 251 287 .. 0.81 7 ? 6.1 0.0 0.047 18 68 92 .. 295 319 .. 291 334 .. 0.86 8 ? 7.8 0.0 0.014 5.4 67 89 .. 334 356 .. 330 364 .. 0.86 9 ? 0.7 0.0 2.2 8.5e+02 69 89 .. 376 396 .. 371 399 .. 0.83 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.082 DUF7018 67 dvqkllekaidhyekslkliee 88 d + +++kai+ yeksl++++e FUN_000343-T1 57 DSRSDFQKAIECYEKSLDIARE 78 66789*************9987 PP == domain 2 score: 6.1 bits; conditional E-value: 0.047 DUF7018 70 kllekaidhyekslklieeavek 92 +l kaid+yeksl++++++ ++ FUN_000343-T1 100 SDLPKAIDYYEKSLNIARKVGDR 122 5899************9987655 PP == domain 3 score: 4.1 bits; conditional E-value: 0.2 DUF7018 69 qkllekaidhyekslklieeavekk 93 ++ kai+ yeksl+++++a ++ FUN_000343-T1 139 ISDFPKAIECYEKSLNIARDAGDQG 163 57999*************9987665 PP == domain 4 score: 4.4 bits; conditional E-value: 0.16 DUF7018 68 vqkllekaidhyekslklieea 89 q ++ kai+ y+ksl+++ ea FUN_000343-T1 175 SQGDFPKAIECYKKSLNIAIEA 196 699*************998776 PP == domain 5 score: 4.0 bits; conditional E-value: 0.2 DUF7018 69 qkllekaidhyekslklieeavek 92 ++ kai+ yeksl+++ ea ++ FUN_000343-T1 216 HSDFPKAIECYEKSLNIASEAGDR 239 57999*************998666 PP == domain 6 score: 3.0 bits; conditional E-value: 0.42 DUF7018 69 qkllekaidhyekslklieea 89 ++ kai+ yeksl+++ ea FUN_000343-T1 256 ISDFPKAIECYEKSLNIAMEA 276 57999***********98887 PP == domain 7 score: 6.1 bits; conditional E-value: 0.047 DUF7018 68 vqkllekaidhyekslklieeavek 92 q +++ka + yeksl++++ea ++ FUN_000343-T1 295 SQGDFTKASECYEKSLNIAREASDR 319 699*****************99877 PP == domain 8 score: 7.8 bits; conditional E-value: 0.014 DUF7018 67 dvqkllekaidhyekslklieea 89 + q ++ kai++yeksl++++e FUN_000343-T1 334 KSQGDFPKAIEYYEKSLNIAREE 356 5799**************99875 PP == domain 9 score: 0.7 bits; conditional E-value: 2.2 DUF7018 69 qkllekaidhyekslklieea 89 +++ +ai+ yeksl+++ ea FUN_000343-T1 376 HRDFPRAIECYEKSLNIAWEA 396 57999**********998765 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 4.9e-05 0.019 11 75 .. 59 123 .. 51 130 .. 0.95 2 ? 1.2 0.0 1.5 5.7e+02 48 74 .. 136 162 .. 128 173 .. 0.79 3 ? 6.7 0.0 0.029 11 10 76 .. 175 241 .. 165 249 .. 0.90 4 ! 10.4 0.1 0.002 0.75 12 75 .. 257 320 .. 250 321 .. 0.94 5 ? 6.8 0.0 0.025 9.7 40 75 .. 325 360 .. 324 365 .. 0.94 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 4.9e-05 ANAPC5 11 akdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 ++d+q+a+++ + D++ ++ ++ + a++nl + ++++++ +A++ e + ++Ar +D a FUN_000343-T1 59 RSDFQKAIECYEKSLDIAREEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRA 123 689*********************************************************99987 PP == domain 2 score: 1.2 bits; conditional E-value: 1.5 ANAPC5 48 hadfghneeAvkaieeaiklArenkDt 74 + ++++ +A++ e + ++Ar+ +D+ FUN_000343-T1 136 YDSISDFPKAIECYEKSLNIARDAGDQ 162 55667778999999*********9997 PP == domain 3 score: 6.7 bits; conditional E-value: 0.029 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 +++d+++a+++ + ++++ ++ + a +nl i + + ++ +A++ e + ++A e +D a+ FUN_000343-T1 175 SQGDFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRAT 241 57899999999999999999999999999999*****************************999875 PP == domain 4 score: 10.4 bits; conditional E-value: 0.002 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 +d+++a+++ + ++++ ++ + a lnl i + + g+ +A + e + ++Are +D a FUN_000343-T1 257 SDFPKAIECYEKSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRA 320 6899999999999999999999999999*********************************975 PP == domain 5 score: 6.8 bits; conditional E-value: 0.025 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDta 75 a +nl + h + g+ +A++ e + ++Are++D a FUN_000343-T1 325 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRA 360 679999***************************975 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.0 0.0028 1.1 12 32 .. 54 74 .. 48 75 .. 0.89 2 ? 1.3 0.0 1.4 5.3e+02 19 32 .. 101 114 .. 86 125 .. 0.84 3 ? 4.7 0.1 0.12 46 13 32 .. 135 154 .. 129 159 .. 0.87 4 ? 8.0 0.0 0.011 4.3 8 33 .. 167 192 .. 161 205 .. 0.83 5 ? 4.2 0.0 0.18 67 11 32 .. 210 231 .. 201 242 .. 0.82 6 ? 6.2 0.0 0.04 15 14 37 .. 253 276 .. 246 287 .. 0.83 7 ? 4.4 0.1 0.15 59 9 33 .. 288 312 .. 281 325 .. 0.81 8 ? 4.9 0.0 0.11 40 16 32 .. 335 351 .. 325 352 .. 0.88 9 ? 3.2 0.0 0.34 1.3e+02 6 32 .. 365 391 .. 361 392 .. 0.80 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0028 MIT 12 veeDnagnyeeAlelYkeale 32 + +D++ ++++A+e+Y+++l+ FUN_000343-T1 54 IIYDSRSDFQKAIECYEKSLD 74 679****************98 PP == domain 2 score: 1.3 bits; conditional E-value: 1.4 MIT 19 nyeeAlelYkeale 32 + +A+++Y+++l+ FUN_000343-T1 101 DLPKAIDYYEKSLN 114 6789*******997 PP == domain 3 score: 4.7 bits; conditional E-value: 0.12 MIT 13 eeDnagnyeeAlelYkeale 32 +D+ ++ +A+e+Y+++l+ FUN_000343-T1 135 AYDSISDFPKAIECYEKSLN 154 5789999**********997 PP == domain 4 score: 8.0 bits; conditional E-value: 0.011 MIT 8 vkkAveeDnagnyeeAlelYkealel 33 ++ + + ++g++ +A+e+Yk++l+ FUN_000343-T1 167 LNLGIAYKSQGDFPKAIECYKKSLNI 192 5667778899*************986 PP == domain 5 score: 4.2 bits; conditional E-value: 0.18 MIT 11 AveeDnagnyeeAlelYkeale 32 + + + ++ +A+e+Y+++l+ FUN_000343-T1 210 GIAYKSHSDFPKAIECYEKSLN 231 56666788999********997 PP == domain 6 score: 6.2 bits; conditional E-value: 0.04 MIT 14 eDnagnyeeAlelYkealelLlqa 37 +D+ ++ +A+e+Y+++l+ + a FUN_000343-T1 253 YDSISDFPKAIECYEKSLNIAMEA 276 789999************987766 PP == domain 7 score: 4.4 bits; conditional E-value: 0.15 MIT 9 kkAveeDnagnyeeAlelYkealel 33 + + + ++g++ +A e+Y+++l+ FUN_000343-T1 288 NLGIAYKSQGDFTKASECYEKSLNI 312 566777889*************986 PP == domain 8 score: 4.9 bits; conditional E-value: 0.11 MIT 16 nagnyeeAlelYkeale 32 ++g++ +A+e+Y+++l+ FUN_000343-T1 335 SQGDFPKAIEYYEKSLN 351 5799**********997 PP == domain 9 score: 3.2 bits; conditional E-value: 0.34 MIT 6 elvkkAveeDnagnyeeAlelYkeale 32 ++++ + + + ++ A+e+Y+++l+ FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEKSLN 391 5666777777889999********997 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.064 25 18 31 .. 59 72 .. 50 74 .. 0.82 2 ? 7.2 0.0 0.03 11 2 31 .. 87 112 .. 86 114 .. 0.76 3 ? 3.9 0.0 0.34 1.3e+02 19 31 .. 140 152 .. 129 154 .. 0.79 4 ? 4.3 0.1 0.25 95 19 31 .. 176 189 .. 163 191 .. 0.65 5 ? 4.4 0.1 0.24 90 19 31 .. 217 229 .. 203 231 .. 0.65 6 ? 3.8 0.0 0.36 1.4e+02 19 31 .. 257 269 .. 246 271 .. 0.80 7 ? -0.3 0.1 7.3 2.8e+03 3 28 .. 285 306 .. 283 312 .. 0.52 8 ? 7.7 0.1 0.021 8 3 31 .. 325 349 .. 323 351 .. 0.69 9 ? 4.1 0.0 0.28 1.1e+02 19 31 .. 377 389 .. 364 391 .. 0.75 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.064 Sel1 18 pkDpekAlewyekA 31 + D +kA+e+yek+ FUN_000343-T1 59 RSDFQKAIECYEKS 72 459*********97 PP == domain 2 score: 7.2 bits; conditional E-value: 0.03 Sel1 2 eAqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG y + D kA+ +yek+ FUN_000343-T1 87 RACFNLGtA-Y-HS---LSDLPKAIDYYEKS 112 589999963.3.55...469999******96 PP == domain 3 score: 3.9 bits; conditional E-value: 0.34 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000343-T1 140 SDFPKAIECYEKS 152 6999*******96 PP == domain 4 score: 4.3 bits; conditional E-value: 0.25 Sel1 19 k.DpekAlewyekA 31 + D kA+e+y+k+ FUN_000343-T1 176 QgDFPKAIECYKKS 189 33999*******96 PP == domain 5 score: 4.4 bits; conditional E-value: 0.24 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000343-T1 217 SDFPKAIECYEKS 229 39999*****996 PP == domain 6 score: 3.8 bits; conditional E-value: 0.36 Sel1 19 kDpekAlewyekA 31 D kA+e+yek+ FUN_000343-T1 257 SDFPKAIECYEKS 269 6999*******96 PP == domain 7 score: -0.3 bits; conditional E-value: 7.3 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewy 28 A+ +LG + +G D kA e+y FUN_000343-T1 285 AYLNLGiAYKSQG-----DFTKASECY 306 6667774322333.....455555555 PP == domain 8 score: 7.7 bits; conditional E-value: 0.021 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG + + D kA+e+yek+ FUN_000343-T1 325 AYFNLGsAHKSQ-----GDFPKAIEYYEKS 349 666666542233.....3999*******96 PP == domain 9 score: 4.1 bits; conditional E-value: 0.28 Sel1 19 kDpekAlewyekA 31 +D +A+e+yek+ FUN_000343-T1 377 RDFPRAIECYEKS 389 799********96 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.089 34 37 64 .. 47 74 .. 30 83 .. 0.82 2 ? 3.1 0.0 0.25 94 28 63 .. 78 113 .. 70 124 .. 0.78 3 ? 6.4 0.0 0.023 8.9 39 78 .. 129 168 .. 122 169 .. 0.83 4 ? 5.9 0.0 0.035 13 37 66 .. 164 193 .. 161 201 .. 0.85 5 ? 3.8 0.0 0.15 56 38 68 .. 205 235 .. 195 242 .. 0.85 6 ! 7.7 0.0 0.0096 3.7 39 72 .. 246 279 .. 240 282 .. 0.90 7 ! 11.9 0.2 0.0005 0.19 37 138 .. 284 388 .. 281 393 .. 0.89 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.089 RPN7 37 raledlaehyakigdlenAlkayerare 64 +a + l+ y + d+++A+++ye+ ++ FUN_000343-T1 47 DASLSLGIIYDSRSDFQKAIECYEKSLD 74 5677899999**************9876 PP == domain 2 score: 3.1 bits; conditional E-value: 0.25 RPN7 28 enlgkeeirraledlaehyakigdlenAlkayerar 63 e+ ra +l+ y++ dl +A+++ye+ + FUN_000343-T1 78 EEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSL 113 55555555677889*******************976 PP == domain 3 score: 6.4 bits; conditional E-value: 0.023 RPN7 39 ledlaehyakigdlenAlkayerarekttslghkidllln 78 + +l++ y +i d+ +A+++ye+ ++ + +g d +ln FUN_000343-T1 129 YFNLGNAYDSISDFPKAIECYEKSLNIARDAGDQGDAYLN 168 66899******************98877777766666665 PP == domain 4 score: 5.9 bits; conditional E-value: 0.035 RPN7 37 raledlaehyakigdlenAlkayerarekt 66 +a+++l+ y + gd+ +A+++y++ ++ + FUN_000343-T1 164 DAYLNLGIAYKSQGDFPKAIECYKKSLNIA 193 689999******************987655 PP == domain 5 score: 3.8 bits; conditional E-value: 0.15 RPN7 38 aledlaehyakigdlenAlkayerarektts 68 a+ +l+ y ++ d+ +A+++ye+ ++ ++ FUN_000343-T1 205 AYFNLGIAYKSHSDFPKAIECYEKSLNIASE 235 67889999***************98876655 PP == domain 6 score: 7.7 bits; conditional E-value: 0.0096 RPN7 39 ledlaehyakigdlenAlkayerarekttslghk 72 + +l++ y +i d+ +A+++ye+ ++ ++ +gh FUN_000343-T1 246 HFNLGNAYDSISDFPKAIECYEKSLNIAMEAGHQ 279 66899*******************9999998885 PP == domain 7 score: 11.9 bits; conditional E-value: 0.0005 RPN7 37 raledlaehyakigdlenAlkayer...arekttslghkidlllnlirvgiffndwalvskylekaksliekggdwerrnrlkvyeGlaalairkf 129 +a+++l+ y + gd+++A ++ye+ + ++++ d ++nl +d+ ++ +y ek ++ + gd+ r+ G+ + + r+f FUN_000343-T1 284 DAYLNLGIAYKSQGDFTKASECYEKslnIAREASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRAREGTAYFNLGITYKSHRDF 379 578999999***************94444556666777789******************************************************* PP RPN7 130 keAakllld 138 +A ++ + FUN_000343-T1 380 PRAIECYEK 388 *99988655 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.1 0.00018 0.07 205 251 .. 66 112 .. 54 119 .. 0.87 2 ? 5.0 0.0 0.029 11 101 142 .. 110 152 .. 109 161 .. 0.81 3 ! 9.5 0.1 0.0012 0.45 205 251 .. 183 229 .. 172 235 .. 0.92 4 ! 7.3 0.1 0.0058 2.2 97 250 .. 223 268 .. 212 278 .. 0.57 5 ! 13.3 0.2 8.8e-05 0.034 91 142 .. 297 349 .. 270 353 .. 0.69 6 ? 4.2 0.0 0.049 19 102 143 .. 348 390 .. 347 396 .. 0.78 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00018 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy + l+ a+e + +++ ac+ l+ y + ++ +ai+++ ++ FUN_000343-T1 66 IECYEKSLDIAREEGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKS 112 6899999999999999999999**********************886 PP == domain 2 score: 5.0 bits; conditional E-value: 0.029 TPR_IF140-IFT172 101 dkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 +k+l++a+k dr + y+n + ++ d+ +ai+ yeks FUN_000343-T1 110 EKSLNIARKVgDRATEGNIYFNLGNAYDSISDFPKAIECYEKS 152 6777888764388888999999999999999999999999987 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0012 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy++ l+ a e +++++ a + l+ y ++ ++ +ai+ + ++ FUN_000343-T1 183 IECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKS 229 78****************************************99875 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0058 TPR_IF140-IFT172 97 sgkwdkalevaekkdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaLesyvkkskdkelkkWwaqylestgeleta 189 FUN_000343-T1 223 I-------------------------------------------------------------------------------------------- 223 3............................................................................................ PP TPR_IF140-IFT172 190 lkyyeaaedylslvrvlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 Cy + l+ a+e + + + + l+ y++ ++ +ai+ + + FUN_000343-T1 224 ----------------ECYEKSLNIASEAGDRATEGNVHFNLGNAYDSISDFPKAIECYEK 268 ................455444444444444444444555556666666666666655554 PP == domain 5 score: 13.3 bits; conditional E-value: 8.8e-05 TPR_IF140-IFT172 91 nklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 ++ +as+ ++k+l++a++ +dr + ++y+n ++gd+ +ai++yeks FUN_000343-T1 297 GDFTKASECYEKSLNIAREaSDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKS 349 45566666677777777532677777777777777777777777777777776 PP == domain 6 score: 4.2 bits; conditional E-value: 0.049 TPR_IF140-IFT172 102 kalevae.kkdrihlrktyynyakhleakgdieeaiklyekse 143 k+l++a+ + dr + ++y+n + +++d+ +ai+ yeks FUN_000343-T1 348 KSLNIAReEGDRAREGTAYFNLGITYKSHRDFPRAIECYEKSL 390 5677775146899999999999999999999999999999985 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.1 0.016 6.2 132 174 .. 64 125 .. 46 128 .. 0.80 2 ? 2.5 0.0 0.43 1.6e+02 149 173 .. 140 164 .. 129 166 .. 0.80 3 ? 5.0 0.0 0.073 28 135 175 .. 164 203 .. 163 205 .. 0.92 4 ? 5.4 0.0 0.053 20 135 174 .. 204 242 .. 203 245 .. 0.90 5 ? 3.3 0.0 0.23 89 150 175 .. 258 283 .. 247 285 .. 0.84 6 ? 6.5 0.1 0.024 9.2 135 175 .. 284 323 .. 283 325 .. 0.92 7 ? 5.2 0.0 0.061 23 135 174 .. 324 362 .. 323 365 .. 0.91 8 ? 2.0 0.0 0.6 2.3e+02 136 171 .. 365 399 .. 363 400 .] 0.89 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.016 DUF7380 132 lAidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrkee 174 Ai++Y +s ++++ +a++++e++l +a+++g+r++e FUN_000343-T1 64 KAIECYEKSLDIAREEgdrarqgracfnlgtayhsLSDLPKAIDYYEKSLNIARKVGDRATE 125 577777766666655566688888888888877776677899****************9987 PP == domain 2 score: 2.5 bits; conditional E-value: 0.43 DUF7380 149 eewvdalkrleRAlqlaaqlgkrke 173 + +a++++e++l +a+ +g++++ FUN_000343-T1 140 SDFPKAIECYEKSLNIARDAGDQGD 164 668899*************999875 PP == domain 3 score: 5.0 bits; conditional E-value: 0.073 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ +++ + +a+++++++l +a ++g++++e FUN_000343-T1 164 DAYLNLGIAYKSQ-GDFPKAIECYKKSLNIAIEAGDQAREG 203 79***99999999.999******************999875 PP == domain 4 score: 5.4 bits; conditional E-value: 0.053 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daY + ++ + +a++++e++l +a ++g+r++e FUN_000343-T1 204 DAYFNLGIAYKSH-SDFPKAIECYEKSLNIASEAGDRATE 242 6899999999998.9999******************9987 PP == domain 5 score: 3.3 bits; conditional E-value: 0.23 DUF7380 150 ewvdalkrleRAlqlaaqlgkrkeep 175 + +a++++e++l +a+++g++++e FUN_000343-T1 258 DFPKAIECYEKSLNIAMEAGHQAREG 283 57899***************999875 PP == domain 6 score: 6.5 bits; conditional E-value: 0.024 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeep 175 daYl+ +++ +++a +++e++l +a+++ +r++e FUN_000343-T1 284 DAYLNLGIAYKSQ-GDFTKASECYEKSLNIAREASDRAREG 323 79***99999999.999******************999875 PP == domain 7 score: 5.2 bits; conditional E-value: 0.061 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daY + + ++++ + +a++++e++l +a++ g+r++e FUN_000343-T1 324 DAYFNLGSAHKSQ-GDFPKAIEYYEKSLNIAREEGDRARE 362 7999999999999.999****************9999887 PP == domain 8 score: 2.0 bits; conditional E-value: 0.6 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkr 171 aY + ++ + + +a++++e++l +a ++g+r FUN_000343-T1 365 AYFNLGITYKSH-RDFPRAIECYEKSLNIAWEAGDR 399 888888899998.9999*************999887 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.17 65 5 55 .. 60 116 .. 56 124 .. 0.84 2 ? 1.9 0.0 1 3.9e+02 6 57 .. 101 158 .. 96 159 .. 0.76 3 ! 11.7 0.0 0.00094 0.36 6 50 .. 141 188 .. 140 193 .. 0.80 4 ? 0.1 0.0 3.9 1.5e+03 22 51 .. 240 269 .. 213 281 .. 0.68 5 ! 9.6 0.0 0.0041 1.6 23 57 .. 281 315 .. 257 322 .. 0.75 6 ? 6.2 0.1 0.048 18 24 57 .. 322 355 .. 306 365 .. 0.70 7 ? 5.4 0.0 0.085 32 4 45 .. 336 383 .. 333 392 .. 0.68 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.17 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaad 55 d+++A++ +e+ l+++ + +a+ +L+ a+ l +l +A+ ++ ++ + FUN_000343-T1 60 SDFQKAIECYEKSLDIAREegdrarQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIA 116 5999********999977776777899999999999999999999998887766665 PP == domain 2 score: 1.9 bits; conditional E-value: 1 TPR_19 6 dydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaadpd 57 d+ +A+ ++e+ l ++ + ++ +L++a+ ++ +A++ ++ ++ ++d FUN_000343-T1 101 DLPKAIDYYEKSLNIARKvgdratEGNIYFNLGNAYDSISDFPKAIECYEKSLNIARD 158 5667788888877665444444458899999999999999999999999988887776 PP == domain 3 score: 11.7 bits; conditional E-value: 0.00094 TPR_19 6 dydeAlalLeqalaedPd...naearllLArallalgrldeAealLaa 50 d+ +A++ +e+ l ++ d +a+l+L+ a+ +g++ +A++ ++ FUN_000343-T1 141 DFPKAIECYEKSLNIARDagdQGDAYLNLGIAYKSQGDFPKAIECYKK 188 677888888886655444445*********************998765 PP == domain 4 score: 0.1 bits; conditional E-value: 3.9 TPR_19 22 PdnaearllLArallalgrldeAealLaal 51 + ++ +L++a+ ++ +A++ ++ FUN_000343-T1 240 ATEGNVHFNLGNAYDSISDFPKAIECYEKS 269 337788899999999999999998887765 PP == domain 5 score: 9.6 bits; conditional E-value: 0.0041 TPR_19 23 dnaearllLArallalgrldeAealLaalpaadpd 57 +a+l+L+ a+ +g++ +A++ ++ ++ +++ FUN_000343-T1 281 REGDAYLNLGIAYKSQGDFTKASECYEKSLNIARE 315 3789********************99998888776 PP == domain 6 score: 6.2 bits; conditional E-value: 0.048 TPR_19 24 naearllLArallalgrldeAealLaalpaadpd 57 +a+ +L+ a+ +g++ +A++ ++ ++ +++ FUN_000343-T1 322 EGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 355 5677888888888888888888877777666665 PP == domain 7 score: 5.4 bits; conditional E-value: 0.085 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAe 45 +gd+ +A++++e+ l ++ + a+ +L+ ++ ++ +A+ FUN_000343-T1 336 QGDFPKAIEYYEKSLNIAREegdrarEGTAYFNLGITYKSHRDFPRAI 383 9************98776653334445555556666666666665555 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.18 68 55 83 .. 51 79 .. 37 85 .. 0.75 2 ? 7.7 0.0 0.011 4.1 56 149 .. 92 191 .. 87 201 .. 0.62 3 ! 11.2 0.0 0.00092 0.35 56 153 .. 132 235 .. 121 240 .. 0.87 4 ! 10.1 0.0 0.0019 0.73 56 155 .. 249 357 .. 244 360 .. 0.78 5 ? 6.5 0.0 0.025 9.6 56 149 .. 289 351 .. 274 399 .. 0.52 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.18 TPR_CcmH_CycH 55 lLGriglslndaetAiqAfekAlklapnn 83 LG i+ s +d ++Ai+ +ek+l++a ++ FUN_000343-T1 51 SLGIIYDSRSDFQKAIECYEKSLDIAREE 79 57777778888888888888888877665 PP == domain 2 score: 7.7 bits; conditional E-value: 0.011 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteikls...YaqaLmlsgdeedlkkAeelLkkll...kqdptnlralsllAfnafeqgdyeeAiaaWq 145 LG + sl+d+ +Ai+ +ek+l++a + + +++ Y ++ ++ +d kA e ++k l ++ ++ +a+ l++ + +qgd+++Ai+ ++ FUN_000343-T1 92 LGTAYHSLSDLPKAIDYYEKSLNIARKVGDRATEgniYFNLGNAYDSISDFPKAIECYEKSLniaRDAGDQGDAYLNLGIAYKSQGDFPKAIECYK 187 666677777777777777777777766555444322366666666666666666666666541113444556777777777777888888887777 PP TPR_CcmH_CycH 146 kmlk 149 k l+ FUN_000343-T1 188 KSLN 191 7665 PP == domain 3 score: 11.2 bits; conditional E-value: 0.00092 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAiaaWq 145 LG + s++d +Ai+ +ek+l++a + + Y ++ + +++ d kA e +kk l+ ++ ++ +a+ l++ + ++ d+++Ai+ ++ FUN_000343-T1 132 LGNAYDSISDFPKAIECYEKSLNIARDAGDQGDAYLNLGIAYKSQGDFPKAIECYKKSLNiaieagDQAREGDAYFNLGIAYKSHSDFPKAIECYE 227 888999999*******************************************9999988644433357788899*********************9 PP TPR_CcmH_CycH 146 kmlkllpa 153 k l++ + FUN_000343-T1 228 KSLNIASE 235 99887665 PP == domain 4 score: 10.1 bits; conditional E-value: 0.0019 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteikl...sYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdyeeAia 142 LG + s++d +Ai+ +ek+l++a + + + Y ++ + +++ d +kA+e ++k l+ + ++ +a+ l+ + +qgd+++Ai+ FUN_000343-T1 249 LGNAYDSISDFPKAIECYEKSLNIAMEAGHQARegdAYLNLGIAYKSQGDFTKASECYEKSLNiareasDRAREGDAYFNLGSAHKSQGDFPKAIE 344 78888899999999999***999998876555422259999999999999999999999887522211134456789999999************* PP TPR_CcmH_CycH 143 aWqkmlkllpadd 155 +++k l++ ++ FUN_000343-T1 345 YYEKSLNIAREEG 357 ***9998877665 PP == domain 5 score: 6.5 bits; conditional E-value: 0.025 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteikls...YaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAiaaWqkml 148 LG + s++d ++A + +ek+l++a + ++ + + Y ++ +++ d kA e ++k l FUN_000343-T1 289 LGIAYKSQGDFTKASECYEKSLNIAREASDRAREgdaYFNLGSAHKSQGDFPKAIEYYEKSL---------------------------------- 350 55555555555555555555555554444333211113333333444444444444444333.................................. PP TPR_CcmH_CycH 149 k 149 + FUN_000343-T1 351 N 351 3 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.079 30 113 153 .] 33 73 .. 26 73 .. 0.84 2 ? 4.7 0.0 0.12 46 5 28 .. 92 115 .. 88 120 .. 0.73 3 ? 3.1 0.0 0.37 1.4e+02 127 153 .] 127 153 .. 120 153 .. 0.84 4 ? 2.5 0.0 0.56 2.1e+02 132 153 .] 169 190 .. 165 192 .. 0.81 5 ? 2.0 0.0 0.81 3.1e+02 8 27 .. 212 231 .. 207 240 .. 0.60 6 ? 2.3 0.0 0.66 2.5e+02 127 153 .] 244 270 .. 234 270 .. 0.79 7 ? 2.3 0.0 0.66 2.5e+02 5 27 .. 249 271 .. 245 281 .. 0.67 8 ? -0.5 0.0 4.9 1.9e+03 133 153 .] 290 310 .. 283 319 .. 0.66 9 ? 6.3 0.0 0.04 15 6 30 .. 330 354 .. 326 361 .. 0.78 10 ? 1.8 0.0 0.98 3.7e+02 131 153 .] 368 390 .. 363 390 .. 0.85 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.079 ARM_TT21_4th 113 eqpdaveeqkklaakiclqlAehaaserdyekaiklYkeAL 153 e++++ ++++ + + +l+l+ + s++d++kai++Y +L FUN_000343-T1 33 ENSSTQTKRRSTQGDASLSLGIIYDSRSDFQKAIECYEKSL 73 5566667778888899999******************9876 PP == domain 2 score: 4.7 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ + kAi+YYe+ l++ FUN_000343-T1 92 LGTAYHSLSDLPKAIDYYEKSLNI 115 566777777777888888888776 PP == domain 3 score: 3.1 bits; conditional E-value: 0.37 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 +i ++l++ + s +d+ kai++Y +L FUN_000343-T1 127 NIYFNLGNAYDSISDFPKAIECYEKSL 153 688899999999999999999998776 PP == domain 4 score: 2.5 bits; conditional E-value: 0.56 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s+ d+ kai++Yk +L FUN_000343-T1 169 LGIAYKSQGDFPKAIECYKKSL 190 5667888999999999999876 PP == domain 5 score: 2.0 bits; conditional E-value: 0.81 ARM_TT21_4th 8 alvktHqYkkAinYYeaalk 27 a+ ++ kAi+ Ye+ l+ FUN_000343-T1 212 AYKSHSDFPKAIECYEKSLN 231 44333356666666666665 PP == domain 6 score: 2.3 bits; conditional E-value: 0.66 ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYkeAL 153 ++ ++l++ + s +d+ kai++Y +L FUN_000343-T1 244 NVHFNLGNAYDSISDFPKAIECYEKSL 270 566788888889999999999998765 PP == domain 7 score: 2.3 bits; conditional E-value: 0.66 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ ++ kAi+ Ye+ l+ FUN_000343-T1 249 LGNAYDSISDFPKAIECYEKSLN 271 46666666666666666666665 PP == domain 8 score: -0.5 bits; conditional E-value: 4.9 ARM_TT21_4th 133 AehaaserdyekaiklYkeAL 153 + + s+ d++ka ++Y +L FUN_000343-T1 290 GIAYKSQGDFTKASECYEKSL 310 445566666666666666544 PP == domain 9 score: 6.3 bits; conditional E-value: 0.04 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalksse 30 G a ++ kAi+YYe+ l++ + FUN_000343-T1 330 GSAHKSQGDFPKAIEYYEKSLNIAR 354 55666666899********998765 PP == domain 10 score: 1.8 bits; conditional E-value: 0.98 ARM_TT21_4th 131 qlAehaaserdyekaiklYkeAL 153 +l+ ++ s+rd+ +ai++Y +L FUN_000343-T1 368 NLGITYKSHRDFPRAIECYEKSL 390 56778999***********9876 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.03 11 147 213 .. 58 123 .. 49 132 .. 0.59 2 ? 4.0 0.0 0.13 48 194 214 .. 104 124 .. 94 165 .. 0.49 3 ? 6.2 0.0 0.027 10 177 213 .. 206 240 .. 164 249 .. 0.64 4 ? 5.2 0.1 0.053 20 166 211 .. 275 318 .. 245 324 .. 0.65 5 ? 5.1 0.1 0.06 23 149 207 .. 297 354 .. 286 362 .. 0.46 6 ? 4.2 0.0 0.11 41 191 211 .. 338 358 .. 325 400 .] 0.47 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.03 ComR_TPR 147 llkdyekleellkvlkeiidktqdf.qkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 + d++k e+ +++ +i ++ d + ++ l y+ d+ kA +Y+k++ a+ +gd + FUN_000343-T1 58 SRSDFQKAIECYEKSLDIAREEGDRaRQGRACFNLGTAYHS--LSDLPKAIDYYEKSLNIARKVGDRA 123 44445555555555555555444431333445555555555..6788888888888888888888765 PP == domain 2 score: 4.0 bits; conditional E-value: 0.13 ComR_TPR 194 kAkelYqkaimfakllgdevL 214 kA +Y+k++ a+ +gd + FUN_000343-T1 104 KAIDYYEKSLNIARKVGDRAT 124 444444444444444444432 PP == domain 3 score: 6.2 bits; conditional E-value: 0.027 ComR_TPR 177 vlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 ++ l y k + df kA e+Y+k++ a+ gd + FUN_000343-T1 206 YFNLGIAY--KSHSDFPKAIECYEKSLNIASEAGDRA 240 44444444..44889999*******999999999976 PP == domain 4 score: 5.2 bits; conditional E-value: 0.053 ComR_TPR 166 dktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 + +++ + +l l y k + df kA e+Y+k++ a+ d FUN_000343-T1 275 EAGHQAREGDAYLNLGIAY--KSQGDFTKASECYEKSLNIAREASD 318 4444444444444444444..45999***********999986665 PP == domain 5 score: 5.1 bits; conditional E-value: 0.06 ComR_TPR 149 kdyekleellkvlkeiidktqdfqkkp.ivlmlewkyylkvkkdfkkAkelYqkaimfak 207 d++k e+ +++ +i +++ d + ++ l + k + df kA e+Y+k++ a+ FUN_000343-T1 297 GDFTKASECYEKSLNIAREASDRAREGdAYFNLGS--AHKSQGDFPKAIEYYEKSLNIAR 354 33444444444444444444333322202222222..22335666666666666666665 PP == domain 6 score: 4.2 bits; conditional E-value: 0.11 ComR_TPR 191 dfkkAkelYqkaimfakllgd 211 df kA e+Y+k++ a+ gd FUN_000343-T1 338 DFPKAIEYYEKSLNIAREEGD 358 444444444444444443333 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.5 1.9e+02 16 30 .. 61 75 .. 57 78 .. 0.61 2 ? 0.3 0.0 1.9 7.2e+02 20 33 .. 105 118 .. 99 121 .. 0.68 3 ? 3.6 0.0 0.18 68 16 30 .. 141 155 .. 137 158 .. 0.83 4 ? 3.3 0.0 0.21 81 17 30 .. 179 192 .. 175 194 .. 0.90 5 ? 3.4 0.0 0.2 77 16 30 .. 218 232 .. 215 236 .. 0.88 6 ? 3.4 0.0 0.2 76 16 30 .. 258 272 .. 254 275 .. 0.82 7 ? 2.8 0.0 0.3 1.1e+02 17 31 .. 299 313 .. 295 317 .. 0.84 8 ? 4.7 0.0 0.078 30 17 30 .. 339 352 .. 335 356 .. 0.85 9 ? 1.5 0.0 0.78 3e+02 17 30 .. 379 392 .. 378 393 .. 0.92 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.5 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F A++ ++k+L++ FUN_000343-T1 61 DFQKAIECYEKSLDI 75 455666666666665 PP == domain 2 score: 0.3 bits; conditional E-value: 1.9 SHNi-TPR 20 AvkDlrkaLeLree 33 A+ ++k+L++ ++ FUN_000343-T1 105 AIDYYEKSLNIARK 118 44457888888665 PP == domain 3 score: 3.6 bits; conditional E-value: 0.18 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000343-T1 141 DFPKAIECYEKSLNI 155 589999999999998 PP == domain 4 score: 3.3 bits; conditional E-value: 0.21 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000343-T1 179 FPKAIECYKKSLNI 192 99**********98 PP == domain 5 score: 3.4 bits; conditional E-value: 0.2 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000343-T1 218 DFPKAIECYEKSLNI 232 5999*********98 PP == domain 6 score: 3.4 bits; conditional E-value: 0.2 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000343-T1 258 DFPKAIECYEKSLNI 272 589999999999997 PP == domain 7 score: 2.8 bits; conditional E-value: 0.3 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F+ A++ ++k+L++ FUN_000343-T1 299 FTKASECYEKSLNIA 313 9999*********95 PP == domain 8 score: 4.7 bits; conditional E-value: 0.078 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000343-T1 339 FPKAIEYYEKSLNI 352 9************9 PP == domain 9 score: 1.5 bits; conditional E-value: 0.78 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000343-T1 379 FPRAIECYEKSLNI 392 8999999*****98 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.9 3.4e+02 34 75 .. 40 78 .. 36 83 .. 0.74 2 ? 4.6 0.0 0.13 48 23 76 .. 143 196 .. 131 200 .. 0.69 3 ? 6.5 0.0 0.032 12 36 75 .. 199 235 .. 176 240 .. 0.70 4 ? 3.0 0.0 0.39 1.5e+02 36 77 .. 279 317 .. 252 320 .. 0.72 5 ! 10.3 0.0 0.0021 0.79 19 75 .. 296 355 .. 287 360 .. 0.73 6 ? -0.3 0.0 4.2 1.6e+03 38 72 .. 361 392 .. 356 398 .. 0.67 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.9 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaee 75 k+ s ++d lG+++ + s++ k a+e + l+ia+e FUN_000343-T1 40 KRRSTQGDASLSLGIIYDSRSDFQK---AIECYEKSLDIARE 78 5567778888889999999999655...66666666777776 PP == domain 2 score: 4.6 bits; conditional E-value: 0.13 Rapsyn_N 23 ekalrvWrkvl...kktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 ka+ + k l +++ d++d + lG+ + G + a+e ++ lnia e FUN_000343-T1 143 PKAIECYEKSLniaRDAGDQGDAYLNLGIAY---KSQGDFPKAIECYKKSLNIAIEA 196 5777788777722255566666666666655...56678888899989999998775 PP == domain 3 score: 6.5 bits; conditional E-value: 0.032 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaee 75 ++ +d + lG+ +++hs++ k e + lnia e FUN_000343-T1 199 QAREGDAYFNLGIAYKSHSDFPKAI---ECYEKSLNIASE 235 4677899999**********88855...555555666666 PP == domain 4 score: 3.0 bits; conditional E-value: 0.39 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeele 77 ++ +d + lG+ +++ ++ k e e + lnia+e FUN_000343-T1 279 QAREGDAYLNLGIAYKSQGDFTKASECYE---KSLNIAREAS 317 46788889999998888877777777665...5578888865 PP == domain 5 score: 10.3 bits; conditional E-value: 0.0021 Rapsyn_N 19 sndtekalrvWrkvl...kktsdredkfrllGylitahsemGkykealefslaqlniaee 75 + d +ka + k l +++sdr l ah G + a+e+ + lnia+e FUN_000343-T1 296 QGDFTKASECYEKSLniaREASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 355 556677777776666333556666555555666779***********************9 PP == domain 6 score: -0.3 bits; conditional E-value: 4.2 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlni 72 + + + lG+ +++h ++ + a+e + lni FUN_000343-T1 361 REGTAYFNLGITYKSHRDFPR---AIECYEKSLNI 392 455667779999999999765...44444455555 PP >> TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.1 0.053 20 55 72 .. 59 76 .. 30 90 .. 0.85 2 ? -1.7 0.0 9.6 3.6e+03 56 72 .. 100 116 .. 91 123 .. 0.76 3 ? 2.4 0.0 0.51 1.9e+02 56 71 .. 140 155 .. 133 162 .. 0.84 4 ? 3.5 0.0 0.23 87 55 71 .. 176 192 .. 161 200 .. 0.82 5 ? 4.8 0.0 0.094 36 54 71 .. 215 232 .. 195 239 .. 0.76 6 ? 4.5 0.0 0.11 43 56 104 .. 257 303 .. 250 311 .. 0.69 7 ? 3.4 0.1 0.24 92 35 70 .. 309 351 .. 290 359 .. 0.59 8 ? 3.7 0.0 0.2 76 55 70 .. 376 391 .. 369 396 .. 0.86 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.053 TPR_BSK1_C 55 akdfktaiecytqfidag 72 + df++aiecy + +d FUN_000343-T1 59 RSDFQKAIECYEKSLDIA 76 579*********999865 PP == domain 2 score: -1.7 bits; conditional E-value: 9.6 TPR_BSK1_C 56 kdfktaiecytqfidag 72 d+ +ai++y + ++ FUN_000343-T1 100 SDLPKAIDYYEKSLNIA 116 57889999999887765 PP == domain 3 score: 2.4 bits; conditional E-value: 0.51 TPR_BSK1_C 56 kdfktaiecytqfida 71 df +aiecy + ++ FUN_000343-T1 140 SDFPKAIECYEKSLNI 155 69********998765 PP == domain 4 score: 3.5 bits; conditional E-value: 0.23 TPR_BSK1_C 55 akdfktaiecytqfida 71 + df +aiecy + ++ FUN_000343-T1 176 QGDFPKAIECYKKSLNI 192 359********998765 PP == domain 5 score: 4.8 bits; conditional E-value: 0.094 TPR_BSK1_C 54 rakdfktaiecytqfida 71 + df +aiecy + ++ FUN_000343-T1 215 SHSDFPKAIECYEKSLNI 232 368*********998876 PP == domain 6 score: 4.5 bits; conditional E-value: 0.11 TPR_BSK1_C 56 kdfktaiecytqfidagtmvsptvyarrslsylmsdkpqeALkdamqaq 104 df +aiecy + ++ +++ ar +yl + + ++ +d ++a FUN_000343-T1 257 SDFPKAIECYEKSLNIA--MEAGHQAREGDAYLNLGIAYKSQGDFTKAS 303 59********9998754..455556666666666666666666655555 PP == domain 7 score: 3.4 bits; conditional E-value: 0.24 TPR_BSK1_C 35 wtqqmqetlnskkkgDaaFr.......akdfktaiecytqfid 70 + +e+ + ++gDa F+ + df +aie+y + ++ FUN_000343-T1 309 SLNIAREASDRAREGDAYFNlgsahksQGDFPKAIEYYEKSLN 351 4444556666666666666332222224588888888887765 PP == domain 8 score: 3.7 bits; conditional E-value: 0.2 TPR_BSK1_C 55 akdfktaiecytqfid 70 ++df aiecy + ++ FUN_000343-T1 376 HRDFPRAIECYEKSLN 391 79*********99876 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.52 2e+02 32 69 .. 55 92 .. 43 112 .. 0.61 2 ? 3.4 0.1 0.36 1.4e+02 4 51 .. 61 114 .. 58 140 .. 0.55 3 ? 1.2 0.0 1.8 6.9e+02 7 56 .. 104 153 .. 98 155 .. 0.68 4 ! 9.9 0.0 0.0033 1.3 5 50 .. 142 191 .. 138 196 .. 0.87 5 ? 6.1 0.0 0.05 19 3 59 .. 217 273 .. 215 278 .. 0.87 6 ? 8.0 0.1 0.013 5 5 50 .. 259 311 .. 255 317 .. 0.82 7 ! 9.3 0.1 0.0051 2 2 50 .. 296 351 .. 295 369 .. 0.81 8 ? 2.5 0.0 0.66 2.5e+02 2 49 .. 336 389 .. 335 393 .. 0.55 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.52 ANAPC3 32 clflngqykrAyellrkaklnekslgcryllAqcllkL 69 + +++++++A+e +k+ + g r +++++ L FUN_000343-T1 55 IYDSRSDFQKAIECYEKSLDIAREEGDRARQGRACFNL 92 56667777777777777744444445555555555544 PP == domain 2 score: 3.4 bits; conditional E-value: 0.36 ANAPC3 4 qyknAiflaerllaaepesped.......ayllAqclflngqykrAyellrkakl 51 +++ Ai ++e+ l + ++++ d + l++++ ++++ +A+++ +k+ + FUN_000343-T1 61 DFQKAIECYEKSL-DIAREEGDrarqgraCFNLGTAYHSLSDLPKAIDYYEKSLN 114 5678888888888.44444444112222144455566666666666666655533 PP == domain 3 score: 1.2 bits; conditional E-value: 1.8 ANAPC3 7 nAiflaerllaaepespedayllAqclflngqykrAyellrka.klneksl 56 Ai ++e+ l ++ d+ + ++ +f++g+ + + + ka +++eksl FUN_000343-T1 104 KAIDYYEKSL-NIARKVGDRATEGNIYFNLGNAYDSISDFPKAiECYEKSL 153 6788888888.7777777777777777877777766666666555555555 PP == domain 4 score: 9.9 bits; conditional E-value: 0.0033 ANAPC3 5 yknAiflaerll..aaepespedayl.lAqclflngqykrAyellrka.k 50 + Ai ++e+ l a ++ + dayl l+ ++ ++g++ +A+e +k+ + FUN_000343-T1 142 FPKAIECYEKSLniARDAGDQGDAYLnLGIAYKSQGDFPKAIECYKKSlN 191 6789********55599999999***88******************9944 PP == domain 5 score: 6.1 bits; conditional E-value: 0.05 ANAPC3 3 hqyknAiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcr 59 ++ Ai ++e+ l + ++ d+ + ++++f++g+ + + + ka +++eksl+ + FUN_000343-T1 217 SDFPKAIECYEKSL-NIASEAGDRATEGNVHFNLGNAYDSISDFPKAiECYEKSLNIA 273 56789*********.999999999999*********9999998888888888888765 PP == domain 6 score: 8.0 bits; conditional E-value: 0.013 ANAPC3 5 yknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka.k 50 + Ai ++e+ l a ++ ++ dayl l+ ++ ++g++++A e +k+ + FUN_000343-T1 259 FPKAIECYEKSLniameAGHQAREGDAYLnLGIAYKSQGDFTKASECYEKSlN 311 5689999999997766557778888899978****************999833 PP == domain 7 score: 9.3 bits; conditional E-value: 0.0051 ANAPC3 2 nhqyknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka.k 50 ++++ A ++e+ l a+++ ++ day l+ ++ ++g++ +A+e+ +k+ + FUN_000343-T1 296 QGDFTKASECYEKSLniareASDRAREGDAYFnLGSAHKSQGDFPKAIEYYEKSlN 351 6778889999999997766546666666677659*****************99933 PP == domain 8 score: 2.5 bits; conditional E-value: 0.66 ANAPC3 2 nhqyknAiflaerll.....a.aepespedayllAqclflngqykrAyellrka 49 ++++ Ai ++e+ l + + +++ + + l+ ++ + ++ rA+e +k+ FUN_000343-T1 336 QGDFPKAIEYYEKSLniareEgDRAREGTAYFNLGITYKSHRDFPRAIECYEKS 389 667888999999999333221222333333444566666666666666666655 PP >> DUF7971 Family of unknown function (DUF7971) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.68 2.6e+02 23 48 .. 58 83 .. 56 92 .. 0.83 2 ? 2.0 0.0 0.87 3.3e+02 26 71 .. 101 151 .. 93 167 .. 0.49 3 ? 3.6 0.0 0.28 1.1e+02 23 50 .. 175 202 .. 172 208 .. 0.86 4 ? 1.7 0.0 1.1 4.2e+02 23 50 .. 215 242 .. 212 249 .. 0.83 5 ? 2.7 0.0 0.53 2e+02 23 50 .. 255 282 .. 250 289 .. 0.83 6 ? -0.1 0.0 3.9 1.5e+03 23 50 .. 295 322 .. 292 327 .. 0.84 7 ? 2.3 0.0 0.69 2.6e+02 22 52 .. 334 364 .. 329 369 .. 0.84 8 ? 1.0 0.0 1.8 7e+02 23 46 .. 375 398 .. 372 400 .] 0.85 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.68 DUF7971 23 aaadmqraveglerrlneaieeadde 48 +++d+q+a+e +e++l+ a ee d FUN_000343-T1 58 SRSDFQKAIECYEKSLDIAREEGDRA 83 678*************9998887765 PP == domain 2 score: 2.0 bits; conditional E-value: 0.87 DUF7971 26 dmqraveglerrlneaieeaddeeeaa.....savvdaierleerleryde 71 d+ +a++ +e++ln a + d +e +++ d i + + +e y++ FUN_000343-T1 101 DLPKAIDYYEKSLNIARKVGDRATEGNiyfnlGNAYDSISDFPKAIECYEK 151 666666666666665555444444322111113334444444444444443 PP == domain 3 score: 3.6 bits; conditional E-value: 0.28 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 ++ d+ +a+e ++++ln aie+ d+ +e FUN_000343-T1 175 SQGDFPKAIECYKKSLNIAIEAGDQARE 202 567999***************9999877 PP == domain 4 score: 1.7 bits; conditional E-value: 1.1 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 +++d+ +a+e +e++ln a e+ d +e FUN_000343-T1 215 SHSDFPKAIECYEKSLNIASEAGDRATE 242 578999***********99988876655 PP == domain 5 score: 2.7 bits; conditional E-value: 0.53 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 + +d+ +a+e +e++ln a+e+ ++ +e FUN_000343-T1 255 SISDFPKAIECYEKSLNIAMEAGHQARE 282 567999**************99877766 PP == domain 6 score: -0.1 bits; conditional E-value: 3.9 DUF7971 23 aaadmqraveglerrlneaieeaddeee 50 ++ d+++a e +e++ln a e++d +e FUN_000343-T1 295 SQGDFTKASECYEKSLNIAREASDRARE 322 5679999**********99999988776 PP == domain 7 score: 2.3 bits; conditional E-value: 0.69 DUF7971 22 eaaadmqraveglerrlneaieeaddeeeaa 52 +++ d+ +a+e +e++ln a ee d +e + FUN_000343-T1 334 KSQGDFPKAIEYYEKSLNIAREEGDRAREGT 364 5678999*************99999887765 PP == domain 8 score: 1.0 bits; conditional E-value: 1.8 DUF7971 23 aaadmqraveglerrlneaieead 46 +++d+ ra+e +e++ln a e+ d FUN_000343-T1 375 SHRDFPRAIECYEKSLNIAWEAGD 398 67899************9988765 PP >> ssDBP Phage single-stranded DNA-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.71 2.7e+02 25 48 .. 91 114 .. 72 124 .. 0.75 2 ? 1.8 0.1 0.85 3.2e+02 18 47 .. 125 153 .. 121 162 .. 0.76 3 ? 7.5 0.0 0.014 5.5 18 55 .. 162 198 .. 156 201 .. 0.87 4 ? 4.8 0.1 0.098 37 18 48 .. 202 231 .. 199 242 .. 0.80 5 ? 2.1 0.0 0.67 2.6e+02 26 54 .. 249 277 .. 236 282 .. 0.80 6 ! 8.4 0.1 0.0073 2.8 18 46 .. 322 349 .. 309 358 .. 0.84 7 ? 3.1 0.0 0.33 1.2e+02 18 54 .. 362 397 .. 350 400 .] 0.78 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.71 ssDBP 25 aeafahledapfPqkisyyveskd 48 + + a+ + + P+ i+yy +s + FUN_000343-T1 91 NLGTAYHSLSDLPKAIDYYEKSLN 114 445567777789*******99954 PP == domain 2 score: 1.8 bits; conditional E-value: 0.85 ssDBP 18 kGnpYtmaeafahledapfPqkisyyvesk 47 +Gn Y ++ + a+ + +fP+ i+ y +s FUN_000343-T1 125 EGNIY-FNLGNAYDSISDFPKAIECYEKSL 153 56666.566778888999******999984 PP == domain 3 score: 7.5 bits; conditional E-value: 0.014 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskdevlpaGe 55 +G++Y ++ + a++++ +fP+ i+ y +s + ++aG+ FUN_000343-T1 162 QGDAY-LNLGIAYKSQGDFPKAIECYKKSLNIAIEAGD 198 67888.567899*****************999999998 PP == domain 4 score: 4.8 bits; conditional E-value: 0.098 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskd 48 +G++Y ++ + a+++ +fP+ i+ y +s + FUN_000343-T1 202 EGDAY-FNLGIAYKSHSDFPKAIECYEKSLN 231 57777.67899***************99965 PP == domain 5 score: 2.1 bits; conditional E-value: 0.67 ssDBP 26 eafahledapfPqkisyyveskdevlpaG 54 + a+ + +fP+ i+ y +s + ++aG FUN_000343-T1 249 LGNAYDSISDFPKAIECYEKSLNIAMEAG 277 4667888899********99988777777 PP == domain 6 score: 8.4 bits; conditional E-value: 0.0073 ssDBP 18 kGnpYtmaeafahledapfPqkisyyves 46 +G++Y ++ + ah+++ +fP+ i+yy +s FUN_000343-T1 322 EGDAY-FNLGSAHKSQGDFPKAIEYYEKS 349 67787.677889**************998 PP == domain 7 score: 3.1 bits; conditional E-value: 0.33 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskdevlpaG 54 +G +Y ++ + +++ +fP+ i+ y +s + +aG FUN_000343-T1 362 EGTAY-FNLGITYKSHRDFPRAIECYEKSLNIAWEAG 397 46666.677899**************99966555555 PP >> Glyoxalase Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.68 2.6e+02 10 29 .. 60 79 .. 58 99 .. 0.82 2 ? 3.9 0.0 0.24 93 10 27 .. 100 117 .. 98 135 .. 0.83 3 ? 1.0 0.0 2 7.5e+02 10 25 .. 140 155 .. 138 165 .. 0.87 4 ? 0.8 0.0 2.3 8.8e+02 10 27 .. 177 194 .. 175 209 .. 0.84 5 ? 0.4 0.0 3 1.2e+03 10 25 .. 217 232 .. 215 248 .. 0.88 6 ? 2.4 0.0 0.73 2.8e+02 10 31 .. 257 278 .. 255 303 .. 0.82 7 ? 2.7 0.0 0.57 2.2e+02 10 30 .. 337 357 .. 328 372 .. 0.82 8 ? -0.6 0.0 6 2.3e+03 10 24 .. 377 391 .. 375 394 .. 0.89 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.68 Glyoxalase 10 gdleksldFYtevLGfklve 29 +d +k++++Y++ L+ e FUN_000343-T1 60 SDFQKAIECYEKSLDIAREE 79 799*********99876655 PP == domain 2 score: 3.9 bits; conditional E-value: 0.24 Glyoxalase 10 gdleksldFYtevLGfkl 27 +dl+k++d+Y++ L+ FUN_000343-T1 100 SDLPKAIDYYEKSLNIAR 117 69**********999765 PP == domain 3 score: 1.0 bits; conditional E-value: 2 Glyoxalase 10 gdleksldFYtevLGf 25 +d +k++++Y++ L+ FUN_000343-T1 140 SDFPKAIECYEKSLNI 155 799*********9986 PP == domain 4 score: 0.8 bits; conditional E-value: 2.3 Glyoxalase 10 gdleksldFYtevLGfkl 27 gd +k++++Y++ L+ + FUN_000343-T1 177 GDFPKAIECYKKSLNIAI 194 799*********999766 PP == domain 5 score: 0.4 bits; conditional E-value: 3 Glyoxalase 10 gdleksldFYtevLGf 25 +d +k++++Y++ L+ FUN_000343-T1 217 SDFPKAIECYEKSLNI 232 6999********9985 PP == domain 6 score: 2.4 bits; conditional E-value: 0.73 Glyoxalase 10 gdleksldFYtevLGfklveet 31 +d +k++++Y++ L+ + + FUN_000343-T1 257 SDFPKAIECYEKSLNIAMEAGH 278 799***********98876655 PP == domain 7 score: 2.7 bits; conditional E-value: 0.57 Glyoxalase 10 gdleksldFYtevLGfklvee 30 gd +k++++Y++ L+ e FUN_000343-T1 337 GDFPKAIEYYEKSLNIAREEG 357 799***********9877665 PP == domain 8 score: -0.6 bits; conditional E-value: 6 Glyoxalase 10 gdleksldFYtevLG 24 +d ++++++Y++ L+ FUN_000343-T1 377 RDFPRAIECYEKSLN 391 6999********997 PP >> Clathrin Region in Clathrin and VPS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.93 3.6e+02 91 110 .. 54 73 .. 47 84 .. 0.78 2 ? 0.8 0.0 1.4 5.3e+02 106 124 .. 96 114 .. 89 117 .. 0.83 3 ? 3.4 0.0 0.21 81 75 114 .. 118 157 .. 116 168 .. 0.79 4 ? 1.3 0.0 0.96 3.6e+02 91 115 .. 171 193 .. 164 206 .. 0.67 5 ? 4.5 0.0 0.1 39 80 111 .. 200 231 .. 193 245 .. 0.75 6 ? 1.8 0.0 0.68 2.6e+02 92 131 .. 252 289 .. 237 301 .. 0.72 7 ? -0.8 0.0 4.3 1.6e+03 91 114 .. 291 314 .. 272 324 .. 0.68 8 ? -0.2 0.0 2.8 1.1e+03 107 124 .. 334 351 .. 302 354 .. 0.77 9 ? 1.4 0.0 0.88 3.4e+02 91 122 .. 371 389 .. 357 397 .. 0.65 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.93 Clathrin 91 ilYkknedwdeaisvlkknk 110 i+Y+ +d+++ai++++k FUN_000343-T1 54 IIYDSRSDFQKAIECYEKSL 73 68888889999999877644 PP == domain 2 score: 0.8 bits; conditional E-value: 1.4 Clathrin 106 lkknklykraieyavkasn 124 +++++++++ai+y++k+ n FUN_000343-T1 96 YHSLSDLPKAIDYYEKSLN 114 899999*******999866 PP == domain 3 score: 3.4 bits; conditional E-value: 0.21 Clathrin 75 kvaklcekaklyeealilYkknedwdeaisvlkknklykr 114 kv++++ + + y + +Y+ ++d+ +ai++++k ++ r FUN_000343-T1 118 KVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNIAR 157 788888888888777779*************777666555 PP == domain 4 score: 1.3 bits; conditional E-value: 0.96 Clathrin 91 ilYkknedwdeaisvlkknklykra 115 i+Yk d+ +ai+++kk +++ a FUN_000343-T1 171 IAYKSQGDFPKAIECYKK--SLNIA 193 567777777777777666..44444 PP == domain 5 score: 4.5 bits; conditional E-value: 0.1 Clathrin 80 cekaklyeealilYkknedwdeaisvlkknkl 111 + + + y + i+Yk ++d+ +ai++++k + FUN_000343-T1 200 AREGDAYFNLGIAYKSHSDFPKAIECYEKSLN 231 5666677777789************9776444 PP == domain 6 score: 1.8 bits; conditional E-value: 0.68 Clathrin 92 lYkknedwdeaisvlkknklykraieyavkasnpelweel 131 +Y+ ++d+ +ai++++k +++ a+e+ +a+ + + +l FUN_000343-T1 252 AYDSISDFPKAIECYEK--SLNIAMEAGHQAREGDAYLNL 289 68899999999998766..666666666666666665555 PP == domain 7 score: -0.8 bits; conditional E-value: 4.3 Clathrin 91 ilYkknedwdeaisvlkknklykr 114 i+Yk d+++a ++++k ++ r FUN_000343-T1 291 IAYKSQGDFTKASECYEKSLNIAR 314 677777788887777555444444 PP == domain 8 score: -0.2 bits; conditional E-value: 2.8 Clathrin 107 kknklykraieyavkasn 124 k+ +++++aiey++k+ n FUN_000343-T1 334 KSQGDFPKAIEYYEKSLN 351 667899999999999866 PP == domain 9 score: 1.4 bits; conditional E-value: 0.88 Clathrin 91 ilYkknedwdeaisvlkknklykraieyavka 122 i Yk + d+ +ai++++k + FUN_000343-T1 371 ITYKSHRDFPRAIECYEK-------------S 389 456666666666666544.............3 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.19 74 7 48 .. 44 85 .. 38 89 .. 0.87 2 ? 3.6 0.0 0.16 59 7 46 .. 84 123 .. 80 129 .. 0.89 3 ? 2.4 0.0 0.35 1.3e+02 9 48 .. 163 202 .. 156 205 .. 0.88 4 ? 0.9 0.0 1 3.8e+02 7 46 .. 201 240 .. 198 249 .. 0.89 5 ! 7.9 0.1 0.0073 2.8 6 48 .. 280 322 .. 275 326 .. 0.92 6 ? 7.1 0.0 0.013 5.1 7 48 .. 321 362 .. 319 376 .. 0.92 7 ? 1.5 0.0 0.65 2.5e+02 7 43 .. 361 397 .. 357 400 .] 0.88 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.19 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarlRk 48 ++ a l+L+ ++ + d+++A ++ + +l+ a+ ++r R+ FUN_000343-T1 44 TQGDASLSLGIIYDSRSDFQKAIECYEKSLDIAREEGDRARQ 85 45667789999999***********************99997 PP == domain 2 score: 3.6 bits; conditional E-value: 0.16 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarl 46 ++ a ++L++ ++ d+ +A Y + +l+ a+++++r FUN_000343-T1 84 RQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRA 123 567899****************************999986 PP == domain 3 score: 2.4 bits; conditional E-value: 0.35 DUF6377 9 naallkLaellyeegdierAykYikvaledakfynarlRk 48 a l+L+ + +gd+ +A ++ k +l+ a +++ R+ FUN_000343-T1 163 GDAYLNLGIAYKSQGDFPKAIECYKKSLNIAIEAGDQARE 202 568899*************************999999886 PP == domain 4 score: 0.9 bits; conditional E-value: 1 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarl 46 +e a ++L+ + + d+ +A ++ + +l+ a+ ++r FUN_000343-T1 201 REGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRA 240 788999**************************99998886 PP == domain 5 score: 7.9 bits; conditional E-value: 0.0073 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlRk 48 +e a l+L+ + +gd+++A+++ + +l+ a+ ++r R+ FUN_000343-T1 280 AREGDAYLNLGIAYKSQGDFTKASECYEKSLNIAREASDRARE 322 689999********************************99996 PP == domain 6 score: 7.1 bits; conditional E-value: 0.013 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarlRk 48 +e a ++L++ +gd+ +A +Y + +l+ a+ ++r R+ FUN_000343-T1 321 REGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAREEGDRARE 362 688899******************************999996 PP == domain 7 score: 1.5 bits; conditional E-value: 0.65 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfyn 43 +e +a ++L+ ++ + d+ rA ++ + +l+ a + FUN_000343-T1 361 REGTAYFNLGITYKSHRDFPRAIECYEKSLNIAWEAG 397 7999*************************99886665 PP >> TPR_IF140_C IF140 C-terminal TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 1.2 4.7e+02 16 41 .. 57 82 .. 54 125 .. 0.72 2 ? 2.4 0.0 0.73 2.8e+02 52 73 .. 131 152 .. 95 190 .. 0.60 3 ? -1.0 0.0 8 3.1e+03 20 41 .. 178 199 .. 172 207 .. 0.75 4 ! 10.3 0.0 0.0026 0.99 19 122 .. 217 308 .. 211 310 .. 0.81 5 ? 2.9 0.0 0.51 1.9e+02 90 122 .. 316 348 .. 309 350 .. 0.86 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 1.2 TPR_IF140_C 16 deyqdYekAlgalkealkclskakek 41 d d++kA+++++++l + + ++ FUN_000343-T1 57 DSRSDFQKAIECYEKSLDIAREEGDR 82 55679999999999999887766554 PP == domain 2 score: 2.4 bits; conditional E-value: 0.73 TPR_IF140_C 52 elkekielikkfveakklyeed 73 +l + + i+ f +a ++ye++ FUN_000343-T1 131 NLGNAYDSISDFPKAIECYEKS 152 5555555555555555555443 PP == domain 3 score: -1.0 bits; conditional E-value: 8 TPR_IF140_C 20 dYekAlgalkealkclskakek 41 d+ kA++++k++l++ +a ++ FUN_000343-T1 178 DFPKAIECYKKSLNIAIEAGDQ 199 7888999999888887777654 PP == domain 4 score: 10.3 bits; conditional E-value: 0.0026 TPR_IF140_C 19 qdYekAlgalkealkclskakeksekekekkleelkekielikkfveakklyeedpeealkqceeLleepdleeavRlgDvyalliehyvkqgnfk 114 d+ kA+++++++l++ s+a ++ + + + +l + + i+ f +a ++ye++ + a+++ + R gD y l +y +qg+f+ FUN_000343-T1 217 SDFPKAIECYEKSLNIASEAGDRAT--EGNVHFNLGNAYDSISDFPKAIECYEKSLNIAMEAG----------HQAREGDAYLNLGIAYKSQGDFT 300 6999999999999999999997643..34445689999999*******999999988888554..........34588999999999999999999 PP TPR_IF140_C 115 kAyellee 122 kA e+ e+ FUN_000343-T1 301 KASECYEK 308 99888775 PP == domain 5 score: 2.9 bits; conditional E-value: 0.51 TPR_IF140_C 90 leeavRlgDvyalliehyvkqgnfkkAyellee 122 + R gD y l +++ +qg+f kA e+ e+ FUN_000343-T1 316 ASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEK 348 55667***********************99875 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.0 0.0071 2.7 133 161 .. 50 78 .. 38 106 .. 0.88 2 ? 0.7 0.0 1.5 5.8e+02 132 159 .. 129 156 .. 91 162 .. 0.74 3 ? 2.8 0.1 0.33 1.3e+02 114 157 .. 145 191 .. 127 201 .. 0.67 4 ? 5.3 0.3 0.059 23 97 161 .. 165 235 .. 158 273 .. 0.65 5 ? -0.4 0.0 3.2 1.2e+03 135 160 .. 249 274 .. 245 281 .. 0.84 6 ? 6.6 0.6 0.024 9.1 97 159 .. 285 353 .. 282 361 .. 0.65 7 ? 1.4 0.0 0.89 3.4e+02 131 158 .. 365 392 .. 360 399 .. 0.83 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0071 ARM_TT21_C 133 ellGliaekeqsykdAaenYekAWklske 161 lG+i+++++ +++A+e+Yek+ +++ e FUN_000343-T1 50 LSLGIIYDSRSDFQKAIECYEKSLDIARE 78 579*******************9887765 PP == domain 2 score: 0.7 bits; conditional E-value: 1.5 ARM_TT21_C 132 yellGliaekeqsykdAaenYekAWkls 159 y lG +++ + + +A+e+Yek+ +++ FUN_000343-T1 129 YFNLGNAYDSISDFPKAIECYEKSLNIA 156 4458999999999********9987665 PP == domain 3 score: 2.8 bits; conditional E-value: 0.33 ARM_TT21_C 114 AeeLlkkvlkynksc...akAyellGliaekeqsykdAaenYekAWk 157 A e +k l+ ++ + Ay lG+ + ++ + +A+e+Y+k+ + FUN_000343-T1 145 AIECYEKSLNIARDAgdqGDAYLNLGIAYKSQGDFPKAIECYKKSLN 191 45555555555544311146888888889999999999999988765 PP == domain 4 score: 5.3 bits; conditional E-value: 0.059 ARM_TT21_C 97 awLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsykdAaenYekAWklske 161 a+L l y ++g + +A e kk l+ + + Ay lG+ + +++ + +A+e+Yek+ ++++e FUN_000343-T1 165 AYLNLGIAYKSQGDFPKAIECYKKSLNIAIEAgdqareGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASE 235 55666666666666666666666666654433111111457888999999999999999999998887654 PP == domain 5 score: -0.4 bits; conditional E-value: 3.2 ARM_TT21_C 135 lGliaekeqsykdAaenYekAWklsk 160 lG +++ + + +A+e+Yek+ +++ FUN_000343-T1 249 LGNAYDSISDFPKAIECYEKSLNIAM 274 6888999999*********9987765 PP == domain 6 score: 6.6 bits; conditional E-value: 0.024 ARM_TT21_C 97 awLlladiyiqsgkldlAeeLlkkvlkynksca.k.....AyellGliaekeqsykdAaenYekAWkls 159 a+L l y ++g + +A+e +k l+ ++ + + Ay lG + ++ + +A+e+Yek+ +++ FUN_000343-T1 285 AYLNLGIAYKSQGDFTKASECYEKSLNIAREASdRaregdAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 353 566666667777777777777777777776654221222255667888888888888888888776665 PP == domain 7 score: 1.4 bits; conditional E-value: 0.89 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWkl 158 Ay lG+ + ++ + A+e+Yek+ ++ FUN_000343-T1 365 AYFNLGITYKSHRDFPRAIECYEKSLNI 392 88889******************97554 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 2.6 1e+03 80 103 .. 52 75 .. 38 77 .. 0.82 2 ? 3.6 0.0 0.18 67 59 101 .. 111 153 .. 105 159 .. 0.91 3 ? 5.6 0.0 0.043 16 40 103 .. 167 232 .. 153 236 .. 0.78 4 ? 7.3 0.0 0.013 4.8 59 101 .. 268 310 .. 241 314 .. 0.86 5 ? -0.2 0.0 2.5 9.5e+02 60 101 .. 349 390 .. 338 393 .. 0.83 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 2.6 TPR_COPA_B 80 lgdlalkkgklklaeeclekakdl 103 lg + ++++++ a ec+ek+ d+ FUN_000343-T1 52 LGIIYDSRSDFQKAIECYEKSLDI 75 5556667899999******99886 PP == domain 2 score: 3.6 bits; conditional E-value: 0.18 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+++ ++a + + + +lg++ + +++ a ec+ek+ FUN_000343-T1 111 KSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSL 153 57999***********************************985 PP == domain 3 score: 5.6 bits; conditional E-value: 0.043 TPR_COPA_B 40 eaLevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeeclekakdl 103 L ++ ++ F a++ ++l++a e ++a++ + + +lg + +++++ a ec+ek+ ++ FUN_000343-T1 167 LNLGIAYKSQGDFPKAIECykKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNI 232 55666666667777777652267999999999999*************************998765 PP == domain 4 score: 7.3 bits; conditional E-value: 0.013 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 ++l++a+e ++a++ + + +lg + ++g+++ a+ec+ek+ FUN_000343-T1 268 KSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKSL 310 6799************************************985 PP == domain 5 score: -0.2 bits; conditional E-value: 2.5 TPR_COPA_B 60 klevalelakeadseqkwkqlgdlalkkgklklaeeclekak 101 +l++a+e ++a++ + + +lg + ++ ++ a ec+ek+ FUN_000343-T1 349 SLNIAREEGDRAREGTAYFNLGITYKSHRDFPRAIECYEKSL 390 5777777777788888899999999999**********9975 PP >> TPR_Slam Surface lipoprotein assembly modifier, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.73 2.8e+02 52 75 .. 51 74 .. 43 83 .. 0.87 2 ? -1.0 0.0 8.6 3.3e+03 58 75 .. 97 114 .. 90 119 .. 0.78 3 ? 4.5 0.0 0.17 64 54 75 .. 170 191 .. 161 197 .. 0.88 4 ? 1.1 0.0 1.9 7.2e+02 53 77 .. 209 233 .. 205 237 .. 0.83 5 ? 1.7 0.1 1.3 4.8e+02 54 77 .. 290 313 .. 285 321 .. 0.85 6 ? 5.3 0.0 0.096 36 55 75 .. 331 351 .. 325 361 .. 0.84 7 ? 1.4 0.0 1.5 5.9e+02 52 75 .. 368 391 .. 359 396 .. 0.86 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.73 TPR_Slam 52 aqAilarsqgnyaeAialYrella 75 + +i+ s+ ++++Ai+ Y++ l+ FUN_000343-T1 51 SLGIIYDSRSDFQKAIECYEKSLD 74 5689999*************9886 PP == domain 2 score: -1.0 bits; conditional E-value: 8.6 TPR_Slam 58 rsqgnyaeAialYrella 75 +s ++ +Ai++Y++ l+ FUN_000343-T1 97 HSLSDLPKAIDYYEKSLN 114 56678899*****99876 PP == domain 3 score: 4.5 bits; conditional E-value: 0.17 TPR_Slam 54 AilarsqgnyaeAialYrella 75 +i +sqg++ +Ai+ Y++ l+ FUN_000343-T1 170 GIAYKSQGDFPKAIECYKKSLN 191 78899*************9876 PP == domain 4 score: 1.1 bits; conditional E-value: 1.9 TPR_Slam 53 qAilarsqgnyaeAialYrellaek 77 +i +s+ ++ +Ai+ Y++ l+ FUN_000343-T1 209 LGIAYKSHSDFPKAIECYEKSLNIA 233 57889999***********998765 PP == domain 5 score: 1.7 bits; conditional E-value: 1.3 TPR_Slam 54 AilarsqgnyaeAialYrellaek 77 +i +sqg++++A + Y++ l+ FUN_000343-T1 290 GIAYKSQGDFTKASECYEKSLNIA 313 78899*************998765 PP == domain 6 score: 5.3 bits; conditional E-value: 0.096 TPR_Slam 55 ilarsqgnyaeAialYrella 75 +sqg++ +Ai++Y++ l+ FUN_000343-T1 331 SAHKSQGDFPKAIEYYEKSLN 351 56799************9886 PP == domain 7 score: 1.4 bits; conditional E-value: 1.5 TPR_Slam 52 aqAilarsqgnyaeAialYrella 75 +i +s++++ +Ai+ Y++ l+ FUN_000343-T1 368 NLGITYKSHRDFPRAIECYEKSLN 391 5689999************99876 PP >> Cohesin_load Cohesin loading factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.008 3 347 428 .. 36 114 .. 20 132 .. 0.75 2 ? 0.5 0.0 0.53 2e+02 402 429 .. 165 192 .. 116 208 .. 0.66 3 ! 10.0 0.0 0.00071 0.27 304 430 .. 210 353 .. 205 378 .. 0.69 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.008 Cohesin_load 347 akaewlkvlrcylliylaflalvrsdwtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspll 428 +++ ++++++ + l++ + +rsd+ ka e+ e+ +++++ + + +++ g+ +++ dl +A +y+++l+ FUN_000343-T1 36 STQTKRRSTQGDASLSLGIIYDSRSDFQKAIECYEKSLDIAREEG---DRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLN 114 555666666666777777788899999999888855555555555...45579999999999999**********9988875 PP == domain 2 score: 0.5 bits; conditional E-value: 0.53 Cohesin_load 402 lhyleglyaqgtgdleaAlaiyqsplls 429 +++ g+ + ++gd +A ++y+++l+ FUN_000343-T1 165 AYLNLGIAYKSQGDFPKAIECYKKSLNI 192 4455688899999999999999777654 PP == domain 3 score: 10.0 bits; conditional E-value: 0.00071 Cohesin_load 304 gvaylpknsddkkaekfleealklleklkkslk..epslslseas.akaewlkvlrcylliylaf..................lalvrsdwtkase 378 g+ay +++ ka+++ e+ l++ ++ ++ + ++ l +a+ + +++ k ++cy + + + ++ +++d+tkase FUN_000343-T1 210 GIAYKSHSDFP-KAIECYEKSLNIASEAGDRATegNVHFNLGNAYdSISDFPKAIECYEKSLNIAmeaghqaregdaylnlgiAYKSQGDFTKASE 304 66666666555.888888888888888877666775566665544144556677777766544444777777777777777778899999999999 PP Cohesin_load 379 sl.eelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspllsl 430 + ++l+ + + s+++ +++ g + ++gd +A ++y+++l+ FUN_000343-T1 305 CYeKSLNIAREASDRA----REGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIA 353 9866666665555544....466677888999999999999999998887655 PP >> TPR_EMC2 EMC2 TPR-like repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 4.2 1.6e+03 67 111 .. 101 151 .. 94 160 .. 0.67 2 ? 5.9 0.0 0.05 19 62 111 .. 173 228 .. 161 236 .. 0.71 3 ? 1.8 0.0 0.91 3.5e+02 67 111 .. 258 308 .. 251 318 .. 0.65 4 ? 0.9 0.0 1.7 6.6e+02 62 91 .. 293 322 .. 284 330 .. 0.76 5 ! 9.0 0.0 0.0055 2.1 62 111 .. 333 388 .. 328 394 .. 0.77 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 4.2 TPR_EMC2 67 dmalaveylnkylelfm......adhdawrelaetyvalqmykqaafcyee 111 d+ a++y +k l++ ++ + + +l ++y ++ + +a cye+ FUN_000343-T1 101 DLPKAIDYYEKSLNIARkvgdraTEGNIYFNLGNAYDSISDFPKAIECYEK 151 666777777777776531111112345677888999999999999999986 PP == domain 2 score: 5.9 bits; conditional E-value: 0.05 TPR_EMC2 62 akaqgdmalaveylnkylelfmadh......dawrelaetyvalqmykqaafcyee 111 k+qgd+ a+e +k l++ + da+ +l +y + + +a cye+ FUN_000343-T1 173 YKSQGDFPKAIECYKKSLNIAIEAGdqaregDAYFNLGIAYKSHSDFPKAIECYEK 228 399***************99886550011125555666666666777778888886 PP == domain 3 score: 1.8 bits; conditional E-value: 0.91 TPR_EMC2 67 dmalaveylnkylelfm.adh.....dawrelaetyvalqmykqaafcyee 111 d+ a+e +k l++ m a h da+ +l +y + + +a+ cye+ FUN_000343-T1 258 DFPKAIECYEKSLNIAMeAGHqaregDAYLNLGIAYKSQGDFTKASECYEK 308 555677777777777663333222226677777777777778888888886 PP == domain 4 score: 0.9 bits; conditional E-value: 1.7 TPR_EMC2 62 akaqgdmalaveylnkylelfmadhdawre 91 k+qgd++ a e +k l++ d re FUN_000343-T1 293 YKSQGDFTKASECYEKSLNIAREASDRARE 322 388999999999999998887777776666 PP == domain 5 score: 9.0 bits; conditional E-value: 0.0055 TPR_EMC2 62 akaqgdmalaveylnkylelfmadhdawre......laetyvalqmykqaafcyee 111 k+qgd+ a+ey +k l++ + d re l ty + + + +a cye+ FUN_000343-T1 333 HKSQGDFPKAIEYYEKSLNIAREEGDRAREgtayfnLGITYKSHRDFPRAIECYEK 388 599*****************998888666522222266777777788888888886 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.087 33 104 172 .. 44 117 .. 24 122 .. 0.77 2 ? 3.2 0.0 0.18 68 113 171 .. 133 193 .. 111 233 .. 0.63 3 ? 3.4 0.0 0.16 60 99 174 .. 163 236 .. 144 271 .. 0.71 4 ? 6.9 0.0 0.014 5.2 100 217 .. 204 317 .. 194 325 .. 0.77 5 ? 7.2 0.0 0.011 4.1 95 173 .. 279 355 .. 261 395 .. 0.85 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.087 TPR_NPHP3 104 alGrflkdlgllsqalpaLqraLeiRetald.....PDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 + G + lg++ + + q+a+e e +ld D +r+ +L + y + +a ++y+++l+i + FUN_000343-T1 44 TQGDASLSLGIIYDSRSDFQKAIECYEKSLDiareeGDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIAR 117 56666677888888888899999999999874444457788888888888888888888888888888888865 PP == domain 2 score: 3.2 bits; conditional E-value: 0.18 TPR_NPHP3 113 gllsqalpaLqraLeiRetald..PDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 g +++ +a+e e +l+ D + ++ +L y g f +a + yk++l+i FUN_000343-T1 133 GNAYDSISDFPKAIECYEKSLNiaRDAGDQGDAYLNLGIAYKSQGDFPKAIECYKKSLNIA 193 3333344444444444444443113444445666677777888888888888888887775 PP == domain 3 score: 3.4 bits; conditional E-value: 0.16 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 d y lG k g +a++ +++L+i a D+ + ++ +L y f +a + y+++l+i +a FUN_000343-T1 163 GDAYLNLGIAYKSQGDFPKAIECYKKSLNIAIEA--GDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEA 236 5677778888888888888888888888887665..6777788888888888888888888888888888887654 PP == domain 4 score: 6.9 bits; conditional E-value: 0.014 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelea...lall 192 d y lG k + +a++ +++L+i a D ++ + +L + y+ f +a + y+++l+i +a G h+ a+e +a l + FUN_000343-T1 204 DAYFNLGIAYKSHSDFPKAIECYEKSLNIASEA--GDRATEGNVHFNLGNAYDSISDFPKAIECYEKSLNIAMEA-G--HQ--AREGDAylnLGIA 292 667777777777777788888888888887776..688888899999999999999**********999998765.3..33..3444432228888 PP TPR_NPHP3 193 yqkqdkhdlaeplkkravairkkak 217 y+ q + a + +++++i ++a FUN_000343-T1 293 YKSQGDFTKASECYEKSLNIAREAS 317 9999999999999999999987754 PP == domain 5 score: 7.2 bits; conditional E-value: 0.011 TPR_NPHP3 95 lakvadlyealGrflkdlgllsqalpaLqraLei.RetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 a+ d y lG k g ++a + +++L+i Re++ D + ++ +L + + g f +a ++y+++l+i ++ FUN_000343-T1 279 QAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIaREAS---DRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIARE 355 4555789999999999999999**********9945554...8899999**************************99865 PP >> TPR_5 Tetratrico peptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.47 1.8e+02 8 46 .. 53 94 .. 46 115 .. 0.67 2 ? 2.8 0.0 0.48 1.8e+02 2 30 .. 127 155 .. 126 178 .. 0.83 3 ? -0.0 0.0 3.7 1.4e+03 10 32 .. 172 194 .. 163 214 .. 0.78 4 ? 4.5 0.0 0.14 55 3 37 .. 245 280 .. 243 320 .. 0.75 5 ? 3.3 0.0 0.34 1.3e+02 3 34 .. 325 356 .. 323 374 .. 0.83 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.47 TPR_5 8 agarDsvGhedkavplYrraLaaGLag...arrrqatiqLas 46 + + Ds + +ka++ Y+++L+ ++ ar+++a L FUN_000343-T1 53 GIIYDSRSDFQKAIECYEKSLDIAREEgdrARQGRACFNLGT 94 567799999999999999999865543111444556655555 PP == domain 2 score: 2.8 bits; conditional E-value: 0.48 TPR_5 2 vaaferagarDsvGhedkavplYrraLaa 30 + f+ + a Ds+ + ka++ Y+++L+ FUN_000343-T1 127 NIYFNLGNAYDSISDFPKAIECYEKSLNI 155 57899999*****************9975 PP == domain 3 score: -0.0 bits; conditional E-value: 3.7 TPR_5 10 arDsvGhedkavplYrraLaaGL 32 a s G+ ka++ Y+++L+ + FUN_000343-T1 172 AYKSQGDFPKAIECYKKSLNIAI 194 667899999********998655 PP == domain 4 score: 4.5 bits; conditional E-value: 0.14 TPR_5 3 aaferagarDsvGhedkavplYrraLaaGLa.garr 37 + f+ + a Ds+ + ka++ Y+++L+ ++ g ++ FUN_000343-T1 245 VHFNLGNAYDSISDFPKAIECYEKSLNIAMEaGHQA 280 6799999*****************998766423333 PP == domain 5 score: 3.3 bits; conditional E-value: 0.34 TPR_5 3 aaferagarDsvGhedkavplYrraLaaGLag 34 a f+ ++a+ s G+ ka++ Y+++L+ ++ FUN_000343-T1 325 AYFNLGSAHKSQGDFPKAIEYYEKSLNIAREE 356 789999*******************9865544 PP >> AimR AimR transcriptional regulator-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.5 5.8e+02 181 201 .. 60 80 .. 35 88 .. 0.80 2 ? 3.7 0.0 0.1 40 144 199 .. 59 118 .. 48 126 .. 0.71 3 ? 6.8 0.2 0.011 4.4 151 203 .. 106 162 .. 96 174 .. 0.72 4 ? 3.6 0.1 0.11 41 149 200 .. 181 236 .. 165 245 .. 0.77 5 ! 7.3 0.1 0.0081 3.1 148 203 .. 223 279 .. 215 289 .. 0.79 6 ? 3.0 0.3 0.17 64 148 200 .. 300 356 .. 286 366 .. 0.64 7 ? 2.5 0.2 0.24 90 149 197 .. 341 393 .. 326 399 .. 0.60 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.5 AimR 181 esYekamkyfekalkiaknee 201 ++++ka++ +ek+l+ia++e FUN_000343-T1 60 SDFQKAIECYEKSLDIAREEG 80 799************999764 PP == domain 2 score: 3.7 bits; conditional E-value: 0.1 AimR 144 rneleearkyakkviensnnprfkal...shltlGnSYl.fesYekamkyfekalkiakn 199 r++ ++a ++++k ++ +++ a + ++lG+ Y ++ ka+ y+ek+l+ia++ FUN_000343-T1 59 RSDFQKAIECYEKSLDIAREEGDRARqgrACFNLGTAYHsLSDLPKAIDYYEKSLNIARK 118 556666666777666666655554433448899999995489999999999999999975 PP == domain 3 score: 6.8 bits; conditional E-value: 0.011 AimR 151 rkyakkviensn...nprfkalshltlGnSY.lfesYekamkyfekalkiakneekk 203 y++k ++ ++ + +++lGn Y ++++ ka++ +ek+l+ia+++ ++ FUN_000343-T1 106 IDYYEKSLNIARkvgDRATEGNIYFNLGNAYdSISDFPKAIECYEKSLNIARDAGDQ 162 45555555554411133445569********779*****************987655 PP == domain 4 score: 3.6 bits; conditional E-value: 0.11 AimR 149 earkyakkviensnnprfkal...shltlGnSYl.fesYekamkyfekalkiakne 200 +a +++kk ++ +++ +a ++++lG Y +++ ka++ +ek+l+ia ++ FUN_000343-T1 181 KAIECYKKSLNIAIEAGDQARegdAYFNLGIAYKsHSDFPKAIECYEKSLNIASEA 236 5667777777777777776666669********75899************999764 PP == domain 5 score: 7.3 bits; conditional E-value: 0.0081 AimR 148 eearkyakkviensnnprfkalshltlGnSY.lfesYekamkyfekalkiakneekk 203 +e+ + + ++ ++ ++ ++h++lGn Y ++++ ka++ +ek+l+ia ++ ++ FUN_000343-T1 223 IECYEKSLNIASEAGDRATEGNVHFNLGNAYdSISDFPKAIECYEKSLNIAMEAGHQ 279 4555566666666667777888*********77*****************9876554 PP == domain 6 score: 3.0 bits; conditional E-value: 0.17 AimR 148 eearkyakkviensnnprfkal...shltlGnSYlfe.sYekamkyfekalkiakne 200 +a+++++k ++ ++ a ++++lG ++ ka++y+ek+l+ia++e FUN_000343-T1 300 TKASECYEKSLNIAREASDRARegdAYFNLGSAHKSQgDFPKAIEYYEKSLNIAREE 356 555566666555555444444333477777777765437888888888888888765 PP == domain 7 score: 2.5 bits; conditional E-value: 0.24 AimR 149 earkyakkviensnnprfkal...shltlGnSYl.fesYekamkyfekalkia 197 +a +y++k ++ +++ a ++++lG +Y ++ a++ +ek+l+ia FUN_000343-T1 341 KAIEYYEKSLNIAREEGDRARegtAYFNLGITYKsHRDFPRAIECYEKSLNIA 393 45556666665555554433222277777777753556777777777776665 PP >> RNPP_C RNPP family C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.1 0.0013 0.5 84 187 .. 51 151 .. 48 176 .. 0.84 2 ? 2.2 0.1 0.41 1.6e+02 86 168 .. 170 250 .. 165 272 .. 0.62 3 ? 5.4 0.2 0.042 16 86 189 .. 210 310 .. 204 336 .. 0.86 4 ? 0.4 0.0 1.4 5.2e+02 91 150 .. 335 392 .. 327 397 .. 0.73 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0013 RNPP_C 84 slAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYqraeclEkldfsee 179 sl ++y + ++k+ie y++ l + + +e d + ++ +n + + d+ +++++ +++++++ + + + G +y+ ++ + + ++ FUN_000343-T1 51 SLGIIYDSRSDFQKAIECYEKSL-DIAREEGD-RARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSIS-DFP 143 7899*******************.66666666.7899*******************************999999999999999998887764.333 PP RNPP_C 180 eiaesykk 187 + e y+k FUN_000343-T1 144 KAIECYEK 151 33455555 PP == domain 2 score: 2.2 bits; conditional E-value: 0.41 RNPP_C 86 AnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYqra 168 + y +g + k+ie y++ l + + + d + + +n + + d+ +++e +++++++ e + + G +++ + FUN_000343-T1 170 GIAYKSQGDFPKAIECYKKSL-NIAIEAGD-QAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIASEAGDRATEGNVHFNLG 250 566778888888888888777.33333333.4555666667666655667777777777777777666655555555555544 PP == domain 3 score: 5.4 bits; conditional E-value: 0.042 RNPP_C 86 AnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYqraeclEkldfseeei 181 + y + + k+ie y++ l + +++ d v +n + d+ +++e ++++++++e + G y + + k ++++ + FUN_000343-T1 210 GIAYKSHSDFPKAIECYEKSL-NIASEAGD-RATEGNVHFNLGNAYDSISDFPKAIECYEKSLNIAMEAGHQAREGDAYLNLG-IAYKSQGDFTKA 302 567888889999******999.77777777.78999********99999*******************999999999988776.566888888888 PP RNPP_C 182 aesykkAl 189 +e y+k l FUN_000343-T1 303 SECYEKSL 310 88888876 PP == domain 4 score: 0.4 bits; conditional E-value: 1.4 RNPP_C 91 eegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaikl 150 +g + k+ie+y++ l + + +e d + +n + ++d+ +++e ++++++ FUN_000343-T1 335 SQGDFPKAIEYYEKSL-NIAREEGD-RAREGTAYFNLGITYKSHRDFPRAIECYEKSLNI 392 6788999999999999.77777766.6666777777776666677888888888877766 PP >> Glyco_hydro_36C Glycosyl hydrolase family 36 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.24 92 53 70 .. 162 179 .. 155 183 .. 0.93 2 ? 1.9 0.0 1.2 4.6e+02 51 70 .. 200 219 .. 186 223 .. 0.86 3 ? 5.9 0.0 0.068 26 50 71 .. 279 300 .. 258 303 .. 0.87 4 ? -0.3 0.0 5.8 2.2e+03 52 70 .. 361 379 .. 343 382 .. 0.83 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.24 Glyco_hydro_36C 53 sGdeLmnaGLnlplegdf 70 +Gd++ n G+ ++++gdf FUN_000343-T1 162 QGDAYLNLGIAYKSQGDF 179 69***************9 PP == domain 2 score: 1.9 bits; conditional E-value: 1.2 Glyco_hydro_36C 51 vysGdeLmnaGLnlplegdf 70 Gd++ n G+ ++++ df FUN_000343-T1 200 AREGDAYFNLGIAYKSHSDF 219 568************99998 PP == domain 3 score: 5.9 bits; conditional E-value: 0.068 Glyco_hydro_36C 50 evysGdeLmnaGLnlplegdfq 71 + Gd++ n G+ ++++gdf+ FUN_000343-T1 279 QAREGDAYLNLGIAYKSQGDFT 300 5568****************96 PP == domain 4 score: -0.3 bits; conditional E-value: 5.8 Glyco_hydro_36C 52 ysGdeLmnaGLnlplegdf 70 G ++ n G++++++ df FUN_000343-T1 361 REGTAYFNLGITYKSHRDF 379 579999*******999998 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 6.7 2.6e+03 2 13 .. 87 98 .. 86 105 .. 0.81 2 ? 5.1 0.0 0.16 62 3 20 .. 165 182 .. 156 186 .. 0.93 3 ? 3.9 0.0 0.42 1.6e+02 3 22 .. 285 304 .. 283 308 .. 0.84 4 ? 1.6 0.0 2.2 8.3e+02 3 20 .. 325 342 .. 323 344 .. 0.89 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 6.7 TPR_4 2 rallaLAralla 13 ra+ +L+ a++ FUN_000343-T1 87 RACFNLGTAYHS 98 899******985 PP == domain 2 score: 5.1 bits; conditional E-value: 0.16 TPR_4 3 allaLArallalGdldeA 20 a+l+L+ a+ +Gd++ A FUN_000343-T1 165 AYLNLGIAYKSQGDFPKA 182 789************998 PP == domain 3 score: 3.9 bits; conditional E-value: 0.42 TPR_4 3 allaLArallalGdldeAra 22 a+l+L+ a+ +Gd+ A + FUN_000343-T1 285 AYLNLGIAYKSQGDFTKASE 304 789***********988865 PP == domain 4 score: 1.6 bits; conditional E-value: 2.2 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ +Gd++ A FUN_000343-T1 325 AYFNLGSAHKSQGDFPKA 342 6789999********988 PP >> CoV_NSP8 Coronavirus replicase NSP8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 2.4 9.2e+02 31 53 .. 62 84 .. 55 91 .. 0.84 2 ? 1.4 0.0 0.91 3.5e+02 32 52 .. 103 123 .. 85 127 .. 0.81 3 ? 0.1 0.0 2.4 9.1e+02 31 50 .. 142 161 .. 130 169 .. 0.77 4 ? 0.8 0.0 1.4 5.5e+02 26 47 .. 174 195 .. 164 202 .. 0.80 5 ? 1.3 0.0 1 3.8e+02 27 52 .. 214 240 .. 204 249 .. 0.79 6 ? -1.7 0.0 8.2 3.1e+03 31 46 .. 259 274 .. 242 282 .. 0.77 7 ? 0.4 0.0 1.9 7.4e+02 29 52 .. 297 320 .. 284 322 .. 0.78 8 ? 5.5 0.0 0.054 21 24 52 .. 331 360 .. 323 365 .. 0.80 9 ? -1.6 0.0 7.9 3e+03 32 51 .. 380 399 .. 372 400 .] 0.78 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 2.4 CoV_NSP8 31 seqllkqlkkalniaksefdrda 53 ++ ++ ++k+l+ia+ e dr + FUN_000343-T1 62 FQKAIECYEKSLDIAREEGDRAR 84 4889999*********9999965 PP == domain 2 score: 1.4 bits; conditional E-value: 0.91 CoV_NSP8 32 eqllkqlkkalniaksefdrd 52 ++ + ++k+lnia+ + dr FUN_000343-T1 103 PKAIDYYEKSLNIARKVGDRA 123 788999*********998885 PP == domain 3 score: 0.1 bits; conditional E-value: 2.4 CoV_NSP8 31 seqllkqlkkalniaksefd 50 ++ ++ ++k+lnia+ + d FUN_000343-T1 142 FPKAIECYEKSLNIARDAGD 161 3789999********97765 PP == domain 4 score: 0.8 bits; conditional E-value: 1.4 CoV_NSP8 26 kangsseqllkqlkkalniaks 47 k +g+ ++ ++ +kk+lnia FUN_000343-T1 174 KSQGDFPKAIECYKKSLNIAIE 195 55677899***********965 PP == domain 5 score: 1.3 bits; conditional E-value: 1 CoV_NSP8 27 angss.eqllkqlkkalniaksefdrd 52 ++ s ++ ++ ++k+lnia + dr FUN_000343-T1 214 KSHSDfPKAIECYEKSLNIASEAGDRA 240 4444448999**********9988885 PP == domain 6 score: -1.7 bits; conditional E-value: 8.2 CoV_NSP8 31 seqllkqlkkalniak 46 ++ ++ ++k+lnia FUN_000343-T1 259 FPKAIECYEKSLNIAM 274 3789999*******95 PP == domain 7 score: 0.4 bits; conditional E-value: 1.9 CoV_NSP8 29 gsseqllkqlkkalniaksefdrd 52 g+ + + ++k+lnia+ + dr FUN_000343-T1 297 GDFTKASECYEKSLNIAREASDRA 320 5556666789********999996 PP == domain 8 score: 5.5 bits; conditional E-value: 0.054 CoV_NSP8 24 ea.kangsseqllkqlkkalniaksefdrd 52 a k +g+ ++ ++ ++k+lnia+ e dr FUN_000343-T1 331 SAhKSQGDFPKAIEYYEKSLNIAREEGDRA 360 452455677****************99996 PP == domain 9 score: -1.6 bits; conditional E-value: 7.9 CoV_NSP8 32 eqllkqlkkalniaksefdr 51 ++ ++ ++k+lnia + dr FUN_000343-T1 380 PRAIECYEKSLNIAWEAGDR 399 678999*******9877666 PP >> DUF6845 Domain of unknown function (DUF6845) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.097 37 8 26 .. 103 121 .. 97 129 .. 0.81 2 ? 1.2 0.0 1.4 5.4e+02 8 30 .. 143 165 .. 137 183 .. 0.82 3 ? -0.5 0.1 4.6 1.7e+03 99 125 .. 291 317 .. 278 322 .. 0.78 4 ? 2.8 0.0 0.44 1.7e+02 9 23 .. 341 355 .. 335 363 .. 0.86 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.097 DUF6845 8 nevieYYntslevlkdvvn 26 + i+YY++sl++ ++v + FUN_000343-T1 103 PKAIDYYEKSLNIARKVGD 121 678************9966 PP == domain 2 score: 1.2 bits; conditional E-value: 1.4 DUF6845 8 nevieYYntslevlkdvvnekdv 30 + ie Y++sl++ +d +++d+ FUN_000343-T1 143 PKAIECYEKSLNIARDAGDQGDA 165 57899***********9998886 PP == domain 3 score: -0.5 bits; conditional E-value: 4.6 DUF6845 99 laYlkdddyakakqlleenkklseels 125 +aY+ + d +ka++ e++ +++ e s FUN_000343-T1 291 IAYKSQGDFTKASECYEKSLNIAREAS 317 689999999999999998888887765 PP == domain 4 score: 2.8 bits; conditional E-value: 0.44 DUF6845 9 evieYYntslevlkd 23 + ieYY++sl++ ++ FUN_000343-T1 341 KAIEYYEKSLNIARE 355 679*********987 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 3.9 1.5e+03 29 44 .. 60 75 .. 51 96 .. 0.76 2 ? 6.0 0.0 0.05 19 24 54 .. 95 125 .. 91 144 .. 0.74 3 ? 2.6 0.0 0.55 2.1e+02 24 65 .. 135 176 .. 130 191 .. 0.75 4 ? -0.3 0.0 4.4 1.7e+03 26 43 .. 214 231 .. 187 258 .. 0.73 5 ? 1.0 0.0 1.7 6.6e+02 24 40 .. 252 268 .. 227 279 .. 0.85 6 ? 1.8 0.0 1 3.8e+02 22 67 .. 329 378 .. 306 389 .. 0.57 7 ? -0.0 0.0 3.7 1.4e+03 26 43 .. 374 391 .. 366 396 .. 0.73 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 3.9 WH_Halo_primase 29 relydAleaYeperew 44 ++ +A+e Ye+ + FUN_000343-T1 60 SDFQKAIECYEKSLDI 75 78899*****987665 PP == domain 2 score: 6.0 bits; conditional E-value: 0.05 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss 54 + hs ++l +A++ Ye+ + +kv ++ + FUN_000343-T1 95 AYHSLSDLPKAIDYYEKSLNIARKVGDRATE 125 579*************999988888887644 PP == domain 3 score: 2.6 bits; conditional E-value: 0.55 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneissprsLgnvLkka 65 + s+++ +A+e Ye+ + +++ ++ +Lg +k++ FUN_000343-T1 135 AYDSISDFPKAIECYEKSLNIARDAGDQGDAYLNLGIAYKSQ 176 567899999******998877777777666666666666665 PP == domain 4 score: -0.3 bits; conditional E-value: 4.4 WH_Halo_primase 26 hsarelydAleaYepere 43 s ++ +A+e Ye+ + FUN_000343-T1 214 KSHSDFPKAIECYEKSLN 231 566788899999998655 PP == domain 5 score: 1.0 bits; conditional E-value: 1.7 WH_Halo_primase 24 efhsarelydAleaYep 40 + s+++ +A+e Ye+ FUN_000343-T1 252 AYDSISDFPKAIECYEK 268 56799999*******97 PP == domain 6 score: 1.8 bits; conditional E-value: 1 WH_Halo_primase 22 lgefhsar.elydAleaYepereweqkvknei...ssprsLgnvLkkard 67 lg h + + +A+e Ye+ + ++ ++ +Lg ++k++rd FUN_000343-T1 329 LGSAHKSQgDFPKAIEYYEKSLNIAREEGDRAregTAYFNLGITYKSHRD 378 55555443377788888888777555555555221334456666666655 PP == domain 7 score: -0.0 bits; conditional E-value: 3.7 WH_Halo_primase 26 hsarelydAleaYepere 43 s r+ +A+e Ye+ + FUN_000343-T1 374 KSHRDFPRAIECYEKSLN 391 567888899999998655 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.57 2.2e+02 64 103 .. 57 96 .. 54 111 .. 0.87 2 ? -1.2 0.0 7 2.7e+03 74 104 .. 107 137 .. 92 159 .. 0.74 3 ? 1.5 0.0 1 3.9e+02 65 104 .. 215 254 .. 213 259 .. 0.90 4 ? 5.8 0.1 0.05 19 64 113 .. 254 303 .. 253 311 .. 0.88 5 ? 4.6 0.1 0.11 43 68 115 .. 298 345 .. 295 356 .. 0.88 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.57 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqay 103 Ds ++++ e ye l++a+ +g ++ + +a +L ay FUN_000343-T1 57 DSRSDFQKAIECYEKSLDIAREEGDRARQGRACFNLGTAY 96 99999******************99998888877777766 PP == domain 2 score: -1.2 bits; conditional E-value: 7 Ulvan_lyase_2nd 74 elyelalnlakrkgyteleekaealLkqayd 104 + ye ln+a++ g ++ e + +L +ayd FUN_000343-T1 107 DYYEKSLNIARKVGDRATEGNIYFNLGNAYD 137 5677788888887777777777666666665 PP == domain 3 score: 1.5 bits; conditional E-value: 1 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqayd 104 sh ++ + e ye ln+a+ g ++ e +++ +L +ayd FUN_000343-T1 215 SHSDFPKAIECYEKSLNIASEAGDRATEGNVHFNLGNAYD 254 788999999**************99999999999988886 PP == domain 4 score: 5.8 bits; conditional E-value: 0.05 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Ds ++ + e ye ln+a g ++ e +a +L ay+++G++ +a FUN_000343-T1 254 DSISDFPKAIECYEKSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKAS 303 666677788999*********************************98765 PP == domain 5 score: 4.6 bits; conditional E-value: 0.11 Ulvan_lyase_2nd 68 kndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpaikt 115 ++++ e ye ln+a+ + ++ e +a +L +a +++G++ +ai++ FUN_000343-T1 298 DFTKASECYEKSLNIAREASDRAREGDAYFNLGSAHKSQGDFPKAIEY 345 6788999**********************************9999865 PP >> SPO22 Meiosis protein SPO22/ZIP4 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.33 1.3e+02 6 67 .. 60 118 .. 58 154 .. 0.81 2 ? 2.3 0.0 0.34 1.3e+02 5 66 .. 176 234 .. 172 276 .. 0.81 3 ? 7.6 0.0 0.0087 3.3 5 66 .. 296 354 .. 291 369 .. 0.74 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.33 SPO22 6 gdldlAehmlskaaednllsldpe.taeeLarllYnigksllskkkyeeavkWLqraldilek 67 +d++ A +++k +l+ e + + r ++n g + +s ++ +a+++ +++l i k FUN_000343-T1 60 SDFQKAIECYEK----SLDIAREEgDRARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARK 118 678888888888....34444333588899999999999999999999999999999998774 PP == domain 2 score: 2.3 bits; conditional E-value: 0.34 SPO22 5 qgdldlAehmlskaaednllsldpetaeeLarllYnigksllskkkyeeavkWLqraldile 66 qgd+ A +++k + + ++++ + + + ++n g++ s +++ +a+ +++l i + FUN_000343-T1 176 QGDFPKAIECYKK-S--LNIAIEAGDQAREGDAYFNLGIAYKSHSDFPKAIECYEKSLNIAS 234 8999999999999.3..667788999999999999999999999999999966666666655 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0087 SPO22 5 qgdldlAehmlskaaednllsldpetaeeLarllYnigksllskkkyeeavkWLqraldile 66 qgd++ A+ +++k + n+ + +++ + + ++n g + s++++ +a+ + +++l i FUN_000343-T1 296 QGDFTKASECYEK-S-LNIARE-ASDRAREGDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAR 354 7888888888888.2.344444.778888888888888888888888888888888888876 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.082 31 220 245 .. 91 116 .. 71 123 .. 0.85 2 ? 0.1 0.0 1.6 6e+02 136 177 .. 194 234 .. 176 255 .. 0.74 3 ? 1.6 0.0 0.58 2.2e+02 135 177 .. 272 314 .. 256 327 .. 0.73 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.082 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqn 245 +++A+ l++ +kA y++k ++ + FUN_000343-T1 91 NLGTAYHSLSDLPKAIDYYEKSLNIA 116 589******************87765 PP == domain 2 score: 0.1 bits; conditional E-value: 1.6 TPR_15 136 aeeeealkkseafwllraelerqegekkaAleayreAltlaP 177 +e+ ++++ a++ l +++ + +++ +A+e+y++ l +a FUN_000343-T1 194 IEAGDQAREGDAYFNLGIAY-KSHSDFPKAIECYEKSLNIAS 234 44556677667777766655.556888899999999998764 PP == domain 3 score: 1.6 bits; conditional E-value: 0.58 TPR_15 135 saee.eealkkseafwllraelerqegekkaAleayreAltlaP 177 a+e +++++ a++ l ++++ +g+ +A e+y++ l +a FUN_000343-T1 272 IAMEaGHQAREGDAYLNLGIAYK-SQGDFTKASECYEKSLNIAR 314 44432667777788887777665.5699999*******998764 PP >> T5_p143 Bacteriophage T5 tail completion protein p143 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.0062 2.4 36 127 .. 55 147 .. 24 154 .. 0.80 2 ? 4.0 0.0 0.13 49 89 127 .. 226 264 .. 200 272 .. 0.81 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0062 T5_p143 36 lkdsarDgtvatvsfkfskPvsedlln.erskkiLkavaesldvqedlgvidalleevagkkskvGrkrstGkvevslGDpadaeegeeaavk 127 + ds++D + a ++ s +++++ + r+ + ++ ++++ +dl + e+ + + kvG + ++G++ +lG++ d+ ++ +a++ FUN_000343-T1 55 IYDSRSDFQKAIECYEKSLDIAREEGDrARQGRACFNLGTAYHSLSDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIE 147 56888888888888888888887775426777888899999999999987777799999999*********************9998888876 PP == domain 2 score: 4.0 bits; conditional E-value: 0.13 T5_p143 89 leevagkkskvGrkrstGkvevslGDpadaeegeeaavk 127 e+ + +s+ G + ++G+v+ +lG++ d+ ++ +a++ FUN_000343-T1 226 YEKSLNIASEAGDRATEGNVHFNLGNAYDSISDFPKAIE 264 56667778999******************9998888876 PP >> Foie-gras_1 Foie gras liver health family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.1 40 164 219 .. 100 155 .. 89 160 .. 0.85 2 ? 4.6 0.0 0.082 31 160 214 .. 213 267 .. 191 277 .. 0.84 3 ? -0.2 0.0 2.3 8.8e+02 170 223 .. 303 356 .. 270 358 .. 0.61 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.1 Foie-gras_1 164 dhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplals 219 + +id ++++l ++k + + ++ ++ ++++++y + d+ ka+e ++ ++ FUN_000343-T1 100 SDLPKAIDYYEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFPKAIECYEKSLNI 155 5566789***********99999999**********************99876555 PP == domain 2 score: 4.6 bits; conditional E-value: 0.082 Foie-gras_1 160 ekgvdhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellr 214 +k+ + +i++++++l +s+ + + ++ ++ ++++++y + d+ ka+e ++ FUN_000343-T1 213 YKSHSDFPKAIECYEKSLNIASEAGDRATEGNVHFNLGNAYDSISDFPKAIECYE 267 5555666679************9999999**********************9987 PP == domain 3 score: -0.2 bits; conditional E-value: 2.3 Foie-gras_1 170 idlLkraleeFskrkqtRlae.elsleiAeEylrlgdwakalellrplalsyrqe 223 ++++++l ++ ++R +e ++++ ++ gd+ ka+e ++ ++ r+e FUN_000343-T1 303 SECYEKSLNIAR-EASDRAREgDAYFNLGSAHKSQGDFPKAIEYYEKSLNIAREE 356 455555555444.333444430344577777888888888887777666666655 PP >> Cdc6_lid Cdc6 AAA+ ATPase-type lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 1.5 5.9e+02 35 56 .. 61 82 .. 56 85 .. 0.88 2 ? -1.3 0.0 7.6 2.9e+03 36 56 .. 102 122 .. 99 127 .. 0.82 3 ? 2.1 0.0 0.68 2.6e+02 28 55 .. 171 198 .. 156 204 .. 0.87 4 ? 0.0 0.0 3 1.1e+03 29 57 .. 212 240 .. 210 246 .. 0.78 5 ? -0.8 0.1 5.5 2.1e+03 28 56 .. 291 319 .. 289 325 .. 0.79 6 ? 5.0 0.0 0.082 31 29 56 .. 332 359 .. 330 362 .. 0.91 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.5 Cdc6_lid 35 DaRrAldlLrkAgelAeregse 56 D +A++ +k+ ++A++eg++ FUN_000343-T1 61 DFQKAIECYEKSLDIAREEGDR 82 77899************99986 PP == domain 2 score: -1.3 bits; conditional E-value: 7.6 Cdc6_lid 36 aRrAldlLrkAgelAeregse 56 + +A+d +k+ ++A++ g++ FUN_000343-T1 102 LPKAIDYYEKSLNIARKVGDR 122 568999999999999998876 PP == domain 3 score: 2.1 bits; conditional E-value: 0.68 Cdc6_lid 28 laaqesGDaRrAldlLrkAgelAeregs 55 +a +++GD +A++ +k+ ++A + g+ FUN_000343-T1 171 IAYKSQGDFPKAIECYKKSLNIAIEAGD 198 677899*********9999999988776 PP == domain 4 score: 0.0 bits; conditional E-value: 3 Cdc6_lid 29 aaqesGDaRrAldlLrkAgelAeregser 57 a +++ D +A++ +k+ ++A + g++ FUN_000343-T1 212 AYKSHSDFPKAIECYEKSLNIASEAGDRA 240 56677788899999999999999988764 PP == domain 5 score: -0.8 bits; conditional E-value: 5.5 Cdc6_lid 28 laaqesGDaRrAldlLrkAgelAeregse 56 +a +++GD +A + +k+ ++A++ ++ FUN_000343-T1 291 IAYKSQGDFTKASECYEKSLNIAREASDR 319 56778999999999999999999877654 PP == domain 6 score: 5.0 bits; conditional E-value: 0.082 Cdc6_lid 29 aaqesGDaRrAldlLrkAgelAeregse 56 a +++GD +A++ +k+ ++A++eg++ FUN_000343-T1 332 AHKSQGDFPKAIEYYEKSLNIAREEGDR 359 56789********************986 PP >> DUF6178 Family of unknown function (DUF6178) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.069 26 306 336 .. 156 186 .. 150 190 .. 0.86 2 ? -1.9 0.0 3 1.2e+03 310 336 .. 200 226 .. 196 229 .. 0.86 3 ? 4.2 0.0 0.043 16 310 337 .. 280 307 .. 273 310 .. 0.87 4 ? -1.2 0.0 1.9 7.4e+02 310 336 .. 360 386 .. 355 389 .. 0.88 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.069 DUF6178 306 lrevvekvagylnLGLelLsggdleraaell 336 r++ ++ +ylnLG+ + s+gd +a e+ FUN_000343-T1 156 ARDAGDQGDAYLNLGIAYKSQGDFPKAIECY 186 688999999*****************99875 PP == domain 2 score: -1.9 bits; conditional E-value: 3 DUF6178 310 vekvagylnLGLelLsggdleraaell 336 +++ +y nLG+ + s++d +a e+ FUN_000343-T1 200 AREGDAYFNLGIAYKSHSDFPKAIECY 226 677889***************999875 PP == domain 3 score: 4.2 bits; conditional E-value: 0.043 DUF6178 310 vekvagylnLGLelLsggdleraaelle 337 +++ +ylnLG+ + s+gd +a+e+ e FUN_000343-T1 280 AREGDAYLNLGIAYKSQGDFTKASECYE 307 678889*****************99866 PP == domain 4 score: -1.2 bits; conditional E-value: 1.9 DUF6178 310 vekvagylnLGLelLsggdleraaell 336 +++ ++y nLG+ + s+ d ra e+ FUN_000343-T1 360 AREGTAYFNLGITYKSHRDFPRAIECY 386 68999****************999875 PP >> NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 5.7 2.2e+03 23 34 .. 61 72 .. 33 85 .. 0.58 2 ? -1.0 0.0 7.8 3e+03 24 37 .. 142 155 .. 110 176 .. 0.66 3 ? 6.3 0.0 0.041 16 21 62 .. 176 217 .. 149 228 .. 0.83 4 ? 0.6 0.0 2.5 9.6e+02 24 44 .. 219 239 .. 215 257 .. 0.77 5 ? 2.6 0.1 0.59 2.2e+02 24 60 .. 259 295 .. 254 320 .. 0.70 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 5.7 NRBF2_MIT 23 kyeeaischkka 34 +++ai c++k+ FUN_000343-T1 61 DFQKAIECYEKS 72 344444444443 PP == domain 2 score: -1.0 bits; conditional E-value: 7.8 NRBF2_MIT 24 yeeaischkkaaay 37 + +ai c++k+ ++ FUN_000343-T1 142 FPKAIECYEKSLNI 155 44555555555443 PP == domain 3 score: 6.3 bits; conditional E-value: 0.041 NRBF2_MIT 21 aGkyeeaischkkaaaylseamkltkseqahlslelqreshi 62 G + +ai c+kk+ ++ ea ++ a + l + +sh FUN_000343-T1 176 QGDFPKAIECYKKSLNIAIEAGDQAREGDAYFNLGIAYKSHS 217 58999****************999999999999999999996 PP == domain 4 score: 0.6 bits; conditional E-value: 2.5 NRBF2_MIT 24 yeeaischkkaaaylseamkl 44 + +ai c++k+ ++ sea FUN_000343-T1 219 FPKAIECYEKSLNIASEAGDR 239 7789*******9999999654 PP == domain 5 score: 2.6 bits; conditional E-value: 0.59 NRBF2_MIT 24 yeeaischkkaaaylseamkltkseqahlslelqres 60 + +ai c++k+ ++ ea + ++ a l l + +s FUN_000343-T1 259 FPKAIECYEKSLNIAMEAGHQAREGDAYLNLGIAYKS 295 5677788888777777777777777777776655444 PP >> BAG6 BCL2-associated athanogene 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.13 50 57 68 .. 91 102 .. 81 110 .. 0.86 2 ? 2.7 0.0 0.39 1.5e+02 53 68 .. 127 142 .. 105 153 .. 0.79 3 ? 1.0 0.0 1.4 5.2e+02 56 68 .. 247 259 .. 234 268 .. 0.82 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.13 BAG6 57 llshalhalSDl 68 +l+ a+h+lSDl FUN_000343-T1 91 NLGTAYHSLSDL 102 79*********9 PP == domain 2 score: 2.7 bits; conditional E-value: 0.39 BAG6 53 EalhllshalhalSDl 68 +++ +l++a+ ++SD FUN_000343-T1 127 NIYFNLGNAYDSISDF 142 48899**********7 PP == domain 3 score: 1.0 bits; conditional E-value: 1.4 BAG6 56 hllshalhalSDl 68 +l++a+ ++SD FUN_000343-T1 247 FNLGNAYDSISDF 259 469*********7 PP >> Ferritin Ferritin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.11 43 88 113 .. 58 83 .. 40 85 .. 0.89 2 ? 0.6 0.0 1.8 7e+02 94 115 .. 104 125 .. 97 127 .. 0.86 3 ? 1.0 0.0 1.4 5.2e+02 94 115 .. 221 242 .. 214 244 .. 0.88 4 ? -0.9 0.0 5.3 2e+03 94 113 .. 341 360 .. 338 362 .. 0.87 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.11 Ferritin 88 alehekkvtkslrelielaeeegDya 113 + + +k+++ +++ ++a+eegD a FUN_000343-T1 58 SRSDFQKAIECYEKSLDIAREEGDRA 83 56789*******************76 PP == domain 2 score: 0.6 bits; conditional E-value: 1.8 Ferritin 94 kvtkslrelielaeeegDyata 115 k+++ +++ ++a+++gD at+ FUN_000343-T1 104 KAIDYYEKSLNIARKVGDRATE 125 789999*************996 PP == domain 3 score: 1.0 bits; conditional E-value: 1.4 Ferritin 94 kvtkslrelielaeeegDyata 115 k+++ +++ ++a e+gD at+ FUN_000343-T1 221 KAIECYEKSLNIASEAGDRATE 242 78999***************97 PP == domain 4 score: -0.9 bits; conditional E-value: 5.3 Ferritin 94 kvtkslrelielaeeegDya 113 k+++ +++ ++a+eegD a FUN_000343-T1 341 KAIEYYEKSLNIAREEGDRA 360 6789999***********76 PP >> RE_NgoFVII_C NgoFVII C-terminal B3-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 3.6 1.4e+03 26 58 .. 153 182 .. 138 188 .. 0.76 2 ? -1.2 0.0 6.3 2.4e+03 23 57 .. 187 221 .. 180 226 .. 0.72 3 ? 0.3 0.0 2.1 7.9e+02 23 55 .. 268 299 .. 255 304 .. 0.70 4 ? 5.6 0.0 0.05 19 18 58 .. 303 342 .. 292 347 .. 0.84 5 ? -1.4 0.0 7.1 2.7e+03 25 56 .. 349 380 .. 341 384 .. 0.76 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.6 RE_NgoFVII_C 26 lNvgqareqrkaprdaYirvpkeitrsefypek 58 lN++ ++daY++++ + +++ +p+ FUN_000343-T1 153 LNIARDA---GDQGDAYLNLGIAYKSQGDFPKA 182 6666544...33679****99999999999875 PP == domain 2 score: -1.2 bits; conditional E-value: 6.3 RE_NgoFVII_C 23 kSglNvgqareqrkaprdaYirvpkeitrsefype 57 k lN++ + ++ +++daY +++ + ++ +p+ FUN_000343-T1 187 KKSLNIAIEAGDQAREGDAYFNLGIAYKSHSDFPK 221 556888666656666899**998887777777765 PP == domain 3 score: 0.3 bits; conditional E-value: 2.1 RE_NgoFVII_C 23 kSglNvgqareqrkaprdaYirvpkeitrsefy 55 kS lN++ + ++ +++daY++++ + +++ + FUN_000343-T1 268 KS-LNIAMEAGHQAREGDAYLNLGIAYKSQGDF 299 44.88866554444689****999888777655 PP == domain 4 score: 5.6 bits; conditional E-value: 0.05 RE_NgoFVII_C 18 geveekSglNvgqareqrkaprdaYirvpkeitrsefypek 58 +e ekS lN++ + ++r +++daY +++++ +++ +p+ FUN_000343-T1 303 SECYEKS-LNIAREASDRAREGDAYFNLGSAHKSQGDFPKA 342 4555665.9****999**99*************99999975 PP == domain 5 score: -1.4 bits; conditional E-value: 7.1 RE_NgoFVII_C 25 glNvgqareqrkaprdaYirvpkeitrsefyp 56 lN++ + +r +++ aY +++ + ++ +p FUN_000343-T1 349 SLNIAREEGDRAREGTAYFNLGITYKSHRDFP 380 49999999899899999988887766666665 PP >> ATP-synt_B ATP synthase B/B' CF(0) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.38 1.4e+02 45 71 .. 58 84 .. 56 87 .. 0.90 2 ? -1.0 0.1 6.4 2.4e+03 42 71 .. 292 321 .. 288 326 .. 0.80 3 ? 3.5 0.0 0.26 98 39 71 .. 329 361 .. 321 365 .. 0.90 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.38 ATP-synt_B 45 rkkeaaaalaeaekalkeAraeAaeii 71 +++++++a++ +ek l Ar e ++ + FUN_000343-T1 58 SRSDFQKAIECYEKSLDIAREEGDRAR 84 689******************998876 PP == domain 2 score: -1.0 bits; conditional E-value: 6.4 ATP-synt_B 42 AeerkkeaaaalaeaekalkeAraeAaeii 71 A +++ ++ +a + +ek l Ar +++ + FUN_000343-T1 292 AYKSQGDFTKASECYEKSLNIAREASDRAR 321 557788899999999999999988777655 PP == domain 3 score: 3.5 bits; conditional E-value: 0.26 ATP-synt_B 39 iaeAeerkkeaaaalaeaekalkeAraeAaeii 71 + +A +++ ++ +a++ +ek l Ar e ++ + FUN_000343-T1 329 LGSAHKSQGDFPKAIEYYEKSLNIAREEGDRAR 361 56899**********************998866 PP >> Glyco_tran_10_N Fucosyltransferase, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 7.5 2.8e+03 86 104 .. 84 102 .. 53 105 .. 0.79 2 ? 4.2 0.0 0.21 81 85 104 .. 200 219 .. 190 222 .. 0.84 3 ? 2.0 0.0 1 3.9e+02 87 104 .. 362 379 .. 347 383 .. 0.80 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 7.5 Glyco_tran_10_N 86 eelenlfNltmtYrrdsdi 104 ++ + fNl Y++ sd+ FUN_000343-T1 84 RQGRACFNLGTAYHSLSDL 102 455679*******999997 PP == domain 2 score: 4.2 bits; conditional E-value: 0.21 Glyco_tran_10_N 85 leelenlfNltmtYrrdsdi 104 +e + +fNl + Y++ sd+ FUN_000343-T1 200 AREGDAYFNLGIAYKSHSDF 219 556789*************7 PP == domain 3 score: 2.0 bits; conditional E-value: 1 Glyco_tran_10_N 87 elenlfNltmtYrrdsdi 104 e +fNl +tY++ d+ FUN_000343-T1 362 EGTAYFNLGITYKSHRDF 379 45679********98886 PP >> DHR-2_Lobe_A DHR-2, Lobe A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.66 2.5e+02 127 149 .. 54 76 .. 49 79 .. 0.86 2 ? -0.3 0.0 4.4 1.7e+03 127 148 .. 211 232 .. 204 237 .. 0.82 3 ? 5.3 0.1 0.086 33 99 149 .. 263 313 .. 251 318 .. 0.81 4 ? 1.7 0.0 1.1 4.1e+02 127 145 .. 371 389 .. 363 395 .. 0.85 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.66 DHR-2_Lobe_A 127 piyekkrdYkklseihkklaely 149 iy+++ d++k e+++k ++ FUN_000343-T1 54 IIYDSRSDFQKAIECYEKSLDIA 76 69**************9987765 PP == domain 2 score: -0.3 bits; conditional E-value: 4.4 DHR-2_Lobe_A 127 piyekkrdYkklseihkklael 148 y+++ d+ k e+++k ++ FUN_000343-T1 211 IAYKSHSDFPKAIECYEKSLNI 232 5799************987665 PP == domain 3 score: 5.3 bits; conditional E-value: 0.086 DHR-2_Lobe_A 99 velleeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaely 149 +e +e+ ++ +a + + y l y+++ d++k se+++k ++ FUN_000343-T1 263 IECYEKSLNIAMEAGHQAREGDAYLNLGIAYKSQGDFTKASECYEKSLNIA 313 667777777777777777777888888899**************9987665 PP == domain 4 score: 1.7 bits; conditional E-value: 1.1 DHR-2_Lobe_A 127 piyekkrdYkklseihkkl 145 +y+++rd+ + e+++k FUN_000343-T1 371 ITYKSHRDFPRAIECYEKS 389 68**************986 PP >> PT26-6P_helical PT26-6P, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 3.7 1.4e+03 65 79 .. 63 77 .. 56 102 .. 0.74 2 ? 5.8 0.1 0.055 21 66 106 .. 104 142 .. 94 152 .. 0.86 3 ? 2.0 0.3 0.8 3.1e+02 39 93 .. 150 206 .. 144 221 .. 0.45 4 ? 1.4 0.1 1.2 4.8e+02 66 106 .. 221 259 .. 190 261 .. 0.81 5 ? 6.2 0.7 0.043 16 35 108 .. 223 301 .. 220 320 .. 0.67 6 ? 1.5 0.1 1.2 4.6e+02 65 79 .. 340 354 .. 307 384 .. 0.73 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 3.7 PT26-6P_helical 65 ekaieayddaiealr 79 +kaie y+++++ r FUN_000343-T1 63 QKAIECYEKSLDIAR 77 799*****9998655 PP == domain 2 score: 5.8 bits; conditional E-value: 0.055 PT26-6P_helical 66 kaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 kai++y+++++ rk+ d + e ++++ ++ i df FUN_000343-T1 104 KAIDYYEKSLNIARKVG--DRATEGNIYFNLGNAYDSISDF 142 9*************995..6677888899999999999998 PP == domain 3 score: 2.0 bits; conditional E-value: 0.8 PT26-6P_helical 39 eekitaaedlkkkadaegne....kakllaekaieayddaiealrkieqtdavdeilla 93 e+ + a d ++ da n k++ kaie y+++++ ie d++ e + FUN_000343-T1 150 EKSLNIARDAGDQGDAYLNLgiayKSQGDFPKAIECYKKSLNI--AIEAGDQAREGDAY 206 4444444444444444443211112222234666666666553..35555555555444 PP == domain 4 score: 1.4 bits; conditional E-value: 1.2 PT26-6P_helical 66 kaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 kaie y+++++ e d + e +++ ++ i df FUN_000343-T1 221 KAIECYEKSLNIAS--EAGDRATEGNVHFNLGNAYDSISDF 259 89999999887543..5667788888888888888888887 PP == domain 5 score: 6.2 bits; conditional E-value: 0.043 PT26-6P_helical 35 issleekitaaedlkkkadaegnekakl.lae.......kaieayddaiealrkieqtdavdeillalkvakkleqiGdfym 108 i+ e+ + a + ++a+ egn + +l a kaie y+++++ +e +++ e +l++ + Gdf FUN_000343-T1 223 IECYEKSLNIASEAGDRAT-EGNVHFNLgNAYdsisdfpKAIECYEKSLNI--AMEAGHQAREGDAYLNLGIAYKSQGDFTK 301 5666777778888888887.7776544323330011122666666666553..35677788888888999999999999964 PP == domain 6 score: 1.5 bits; conditional E-value: 1.2 PT26-6P_helical 65 ekaieayddaiealr 79 kaie+y+++++ r FUN_000343-T1 340 PKAIEYYEKSLNIAR 354 599*****9987655 PP >> Phage_tail_tube_init Putative phage tail tube initiator protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.27 1e+02 144 178 .. 109 143 .. 95 177 .. 0.83 2 ? 4.3 0.0 0.1 39 144 179 .. 226 261 .. 210 288 .. 0.79 3 ? 0.3 0.0 1.7 6.6e+02 144 179 .. 306 341 .. 304 372 .. 0.77 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.27 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeks 178 Ye +l + rk ++ + e + +++GN + s+++ FUN_000343-T1 109 YEKSLNIARKVGDRATEGNIYFNLGNAYDSISDFP 143 9999************************9999866 PP == domain 2 score: 4.3 bits; conditional E-value: 0.1 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksd 179 Ye +l + +a++ + e v +++GN + s+++ + FUN_000343-T1 226 YEKSLNIASEAGDRATEGNVHFNLGNAYDSISDFPK 261 9999*************************9998664 PP == domain 3 score: 0.3 bits; conditional E-value: 1.7 Phage_tail_tube_init 144 YeiklvvlrkasepddedvvdpeiGNrfpsleeksd 179 Ye +l + r+as+ ++e + +++G +s ++ + FUN_000343-T1 306 YEKSLNIAREASDRAREGDAYFNLGSAHKSQGDFPK 341 889999***********9999****99999877654 PP >> DUF6591 Family of unknown function (DUF6591) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.8 0.0013 0.48 99 155 .. 12 74 .. 3 78 .. 0.70 2 ? -1.3 0.0 5.4 2.1e+03 139 155 .. 215 231 .. 184 236 .. 0.78 3 ? -0.0 0.1 2.3 8.8e+02 136 159 .. 252 275 .. 224 302 .. 0.72 4 ? -0.8 0.1 3.9 1.5e+03 132 155 .. 328 351 .. 294 353 .. 0.55 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0013 DUF6591 99 eeedaakedsessdeadtsaeeeepeetssdssteaeasd.......lrpdfkaamDsYEafmd 155 +e d a+ +ssd+++ ++e+++++t+ st+ +as r+df++a++ YE+ +d FUN_000343-T1 12 TEGDCASPAGSSSDAHEGRTTENSSTQTK-RRSTQGDASLslgiiydSRSDFQKAIECYEKSLD 74 45556666666677666666666665554.555555555567888889************9887 PP == domain 2 score: -1.3 bits; conditional E-value: 5.4 DUF6591 139 lrpdfkaamDsYEafmd 155 ++df +a++ YE+ ++ FUN_000343-T1 215 SHSDFPKAIECYEKSLN 231 57899999999999887 PP == domain 3 score: -0.0 bits; conditional E-value: 2.3 DUF6591 136 asdlrpdfkaamDsYEafmdeYve 159 a d +df +a++ YE+ ++ +e FUN_000343-T1 252 AYDSISDFPKAIECYEKSLNIAME 275 334679**********99986555 PP == domain 4 score: -0.8 bits; conditional E-value: 3.9 DUF6591 132 teaeasdlrpdfkaamDsYEafmd 155 + +a++ + df +a++ YE+ ++ FUN_000343-T1 328 NLGSAHKSQGDFPKAIEYYEKSLN 351 223344467888888888888776 PP >> NSF Aromatic-di-Alanine (AdAR) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 1.1 4.1e+02 1 7 [. 65 71 .. 62 75 .. 0.76 2 ? 1.8 0.1 2.9 1.1e+03 1 10 [. 105 114 .. 105 116 .. 0.81 3 ? 3.3 0.1 0.88 3.4e+02 1 10 [. 145 154 .. 145 156 .. 0.81 4 ? 0.9 0.1 5.8 2.2e+03 1 7 [. 182 188 .. 181 193 .. 0.73 5 ? 3.3 0.1 0.88 3.4e+02 1 10 [. 222 231 .. 222 233 .. 0.81 6 ? 3.3 0.1 0.88 3.4e+02 1 10 [. 262 271 .. 262 273 .. 0.81 7 ? 2.4 0.0 1.8 7e+02 7 12 .] 301 306 .. 299 312 .. 0.63 8 ? 1.5 0.2 3.7 1.4e+03 1 10 [. 342 351 .. 342 353 .. 0.80 9 ? 3.3 0.1 0.88 3.4e+02 1 10 [. 382 391 .. 382 393 .. 0.81 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 1.1 NSF 1 Aakhyek 7 A+++yek FUN_000343-T1 65 AIECYEK 71 7778877 PP == domain 2 score: 1.8 bits; conditional E-value: 2.9 NSF 1 AakhyekAae 10 A+++yek + FUN_000343-T1 105 AIDYYEKSLN 114 99****9755 PP == domain 3 score: 3.3 bits; conditional E-value: 0.88 NSF 1 AakhyekAae 10 A+++yek + FUN_000343-T1 145 AIECYEKSLN 154 99****9755 PP == domain 4 score: 0.9 bits; conditional E-value: 5.8 NSF 1 Aakhyek 7 A+++y k FUN_000343-T1 182 AIECYKK 188 7888877 PP == domain 5 score: 3.3 bits; conditional E-value: 0.88 NSF 1 AakhyekAae 10 A+++yek + FUN_000343-T1 222 AIECYEKSLN 231 99****9755 PP == domain 6 score: 3.3 bits; conditional E-value: 0.88 NSF 1 AakhyekAae 10 A+++yek + FUN_000343-T1 262 AIECYEKSLN 271 99****9755 PP == domain 7 score: 2.4 bits; conditional E-value: 1.8 NSF 7 kAaeiy 12 kA+e+y FUN_000343-T1 301 KASECY 306 555555 PP == domain 8 score: 1.5 bits; conditional E-value: 3.7 NSF 1 AakhyekAae 10 A+++yek + FUN_000343-T1 342 AIEYYEKSLN 351 89****9655 PP == domain 9 score: 3.3 bits; conditional E-value: 0.88 NSF 1 AakhyekAae 10 A+++yek + FUN_000343-T1 382 AIECYEKSLN 391 99****9755 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (400 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 625 (0.0244666); expected 510.9 (0.02) Passed bias filter: 518 (0.0202779); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 68 (0.00266197); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 67 [number of targets reported over threshold] # CPU time: 0.58u 0.35s 00:00:00.93 Elapsed: 00:00:00.47 # Mc/sec: 3450.49 // Query: FUN_000344-T1 [L=309] Description: FUN_000344 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-14 53.4 10.1 4.9e-07 30.4 0.7 2.2 2 DED Death effector domain ------ inclusion threshold ------ 0.011 16.0 0.3 0.037 14.4 0.2 1.7 2 TK Thymidine kinase 0.058 14.2 1.3 0.46 11.3 1.3 2.1 1 MutS_III MutS domain III 0.27 11.6 2.3 0.25 11.7 0.5 1.9 2 Mu_Gam-Sipho_Gp157-TOTE Mu Gam/Sipho_Gp157-like domain of th Domain annotation for each model (and alignments): >> DED Death effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.7 7.7e-11 4.9e-07 1 79 [. 6 85 .. 6 87 .. 0.92 2 ! 27.4 2.9 6.6e-10 4.2e-06 15 81 .. 107 175 .. 92 176 .. 0.81 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 7.7e-11 DED 1 frklLleiseeLtseelesLk.FLlkdkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkieky 79 ++ lL++is +L+ + L +++k++++ ++i++ l+l++ Le+ l+ d ++ ++++L+ +++ dL + + FUN_000344-T1 6 YNTLLYHISRQLDAIDALGLVrLICEEKLGHQAHQDIQDTLSLLKKLEESSFLGVDEMQDVKDILKAVNQWDLYDDVVMF 85 789***********99888873669999*********************************************9887665 PP == domain 2 score: 27.4 bits; conditional E-value: 6.6e-10 DED 15 eelesLk.FLlk.dkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +le L+ ++ ++ipk++ ++i+++++lf+ Le+ + l+ d+l +L+++++++k+++Ll+++ +++k FUN_000344-T1 107 RDLERLMsIVCRvKRIPKERKNNIHDVRSLFQVLEDINCLGIDRLGILRDIFNEMKKDELLTELGEFQK 175 566666525677355************************************************999987 PP >> TK Thymidine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.2 5.8e-06 0.037 61 139 .. 40 115 .. 21 134 .. 0.71 2 ? -0.3 0.0 0.18 1.2e+03 55 94 .. 122 159 .. 107 165 .. 0.70 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 5.8e-06 TK 61 sktssledikeeleeedvdvvlvDEaqFfedivelseklanegkivivagLdtdFerklFenilkllalaekvkklkav 139 ++++ ++ ++le + + ++vDE q +di++ ++++ ++ +v+ +++ ++++ l i +l l + +++l + FUN_000344-T1 40 QDIQDTLSLLKKLE--ESSFLGVDEMQDVKDILKAVNQWDLYDDVVMFESMRREYKELLERVINELEGLRD-LERLMSI 115 33444444444444..4899***********************************9776666666655544.4444443 PP == domain 2 score: -0.3 bits; conditional E-value: 0.18 TK 55 sleakksktssledikeeleeedvdvvlvDEaqFfedive 94 + + +k++++ + ++ ++le+ ++++++D ++di + FUN_000344-T1 122 IPKERKNNIHDVRSLFQVLED--INCLGIDRLGILRDIFN 159 444445667777777777766..9******9888888765 PP >> MutS_III MutS domain III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 1.3 7.2e-05 0.46 65 116 .. 93 151 .. 8 281 .. 0.68 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7.2e-05 xxxxxxxxxxxxxxxxxxxxxx......xxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx RF MutS_III 65 selreelreslkklpDlerlls......rialgka.kprdllallesleklpelkella 116 +el e++ ++l++l+Dlerl+s ri +++ + d+++l + le ++ l + FUN_000344-T1 93 KELLERVINELEGLRDLERLMSivcrvkRIPKERKnNIHDVRSLFQVLEDINCLGIDRL 151 567888999999999******96665555555554345555555555553332222222 PP >> Mu_Gam-Sipho_Gp157-TOTE Mu Gam/Sipho_Gp157-like domain of the TOTE conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 1.4 9.1e+03 7 30 .. 81 104 .. 77 106 .. 0.57 2 ? 11.7 0.5 4e-05 0.25 29 56 .. 154 181 .. 152 184 .. 0.92 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 1.4 Mu_Gam-Sipho_Gp157-TOTE 7 elveLkkqrrelskeikkyeekLe 30 ++v + rre + + ++ ++Le FUN_000344-T1 81 DVVMFESMRREYKELLERVINELE 104 555555556666666666666555 PP == domain 2 score: 11.7 bits; conditional E-value: 4e-05 Mu_Gam-Sipho_Gp157-TOTE 29 LedlFksagvdeveidiGkLvRvdende 56 L+d+F++ + de+ +++G + +++ +de FUN_000344-T1 154 LRDIFNEMKKDELLTELGEFQKRRIEDE 181 89********************999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1226 (0.0479937); expected 510.9 (0.02) Passed bias filter: 843 (0.0330006); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.42s 00:00:00.74 Elapsed: 00:00:00.49 # Mc/sec: 2533.70 // Query: FUN_000345-T1 [L=1325] Description: FUN_000345 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-49 166.7 1.1 2.1e-13 50.7 0.0 5.7 5 TPR_12 Tetratricopeptide repeat 3.1e-48 160.2 20.6 2.3e-07 30.8 0.2 9.5 9 TPR_1 Tetratricopeptide repeat 1.8e-36 121.7 16.3 4.9e-05 23.6 0.0 9.5 9 TPR_2 Tetratricopeptide repeat 9.7e-34 113.1 0.0 0.00081 19.8 0.0 10.1 9 TPR_7 Tetratricopeptide repeat 1.4e-23 81.5 15.1 7.5e-05 23.1 0.2 8.3 8 TPR_8 Tetratricopeptide repeat 3.8e-17 63.0 0.8 1e-16 61.6 0.8 1.8 1 COR-A C-terminal of Roc, COR-A domain 6.2e-17 62.4 15.1 1.7e-08 34.8 0.7 2.9 3 SNAP Soluble NSF attachment protein, SNAP 3.5e-15 56.8 0.1 4.3e-06 27.5 0.1 3.0 2 Roc Ras of Complex, Roc, domain of DAPkinase 4.6e-14 52.4 0.0 1.8 9.2 0.0 7.4 7 TPR_10 Tetratricopeptide repeat 2.2e-11 43.6 0.3 2.3 9.2 0.0 7.8 6 TPR_17 Tetratricopeptide repeat 3.6e-10 39.9 17.9 0.68 10.2 0.1 10.9 10 TPR_11 TPR repeat 5.2e-10 39.8 0.0 0.69 11.2 0.0 7.6 6 TPR_6 Tetratricopeptide repeat 1.5e-08 34.8 0.0 0.0011 18.8 0.0 2.9 2 TPR_MalT MalT-like TPR region 4.1e-08 33.6 1.3 0.0024 18.1 0.0 3.3 3 RPN7 26S proteasome subunit RPN7 1.2e-07 32.5 0.2 0.94 10.5 0.0 5.9 6 TPR_16 Tetratricopeptide repeat 8.4e-07 29.5 0.2 0.71 10.5 0.0 5.4 5 ANAPC5 Anaphase-promoting complex subunit 5 9.1e-06 25.0 7.9 0.17 10.9 0.1 5.0 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.9e-05 24.9 0.1 13 5.8 0.0 5.5 5 ComR_TPR ComR tetratricopeptide 2.7e-05 24.6 0.0 30 5.2 0.0 5.3 5 TPR_9 Tetratricopeptide repeat 5.7e-05 23.6 5.3 7.1 7.3 0.0 6.4 6 MIT MIT (microtubule interacting and transport) 6.4e-05 23.4 0.0 35 5.1 0.0 5.9 7 Rapsyn_N Rapsyn N-terminal myristoylation and linker 7.9e-05 23.0 1.5 7.1 7.0 0.0 6.0 6 TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, 8.7e-05 22.4 0.0 28 4.8 0.0 6.5 7 SHNi-TPR SHNi-TPR 0.00016 21.8 0.1 0.23 11.5 0.0 2.4 2 Ras Ras family 0.00026 21.9 0.1 1.1e+02 4.4 0.0 5.9 4 TPR_14 Tetratricopeptide repeat 0.0045 17.5 0.2 39 4.7 0.0 4.7 5 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain 0.0062 16.9 7.0 5 7.6 0.0 5.6 6 ssDBP Phage single-stranded DNA-binding protein 0.0068 16.3 0.1 11 5.8 0.0 3.6 4 TPR_NPHP3 Nephrocystin-3 TPR domain 0.0081 16.5 3.4 19 5.5 0.2 5.2 5 DUF7380 Domain of unknown function (DUF7380) 0.009 16.3 2.2 95 3.2 0.1 5.6 5 Clathrin Region in Clathrin and VPS 0.0098 16.9 2.5 30 5.9 0.0 5.5 4 Sel1 Sel1 repeat ------ inclusion threshold ------ 0.012 16.3 0.0 1.3e+02 3.3 0.0 5.8 5 DUF7018 Domain of unknown function (DUF7018) 0.051 14.3 1.8 1.6e+02 2.9 0.0 5.6 5 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth A 0.059 13.7 0.0 0.12 12.6 0.0 1.5 1 PduV-EutP Ethanolamine utilisation - propanediol util 0.13 12.8 0.1 78 3.9 0.0 4.0 4 Cerato-platanin Cerato-platanin 0.17 12.9 0.0 1.5e+02 3.3 0.0 4.5 4 Glyco_tran_10_N Fucosyltransferase, N-terminal 0.19 11.8 0.1 23 5.0 0.0 3.0 3 Foie-gras_1 Foie gras liver health family 1 0.22 11.9 4.7 40 4.4 0.3 4.7 5 ARM_TT21_C Tetratricopeptide repeat protein 21 C-termi Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 5.1e-06 0.0034 18 77 .] 26 83 .. 25 83 .. 0.87 2 ! 50.7 0.0 3.1e-16 2.1e-13 5 77 .] 93 163 .. 89 163 .. 0.96 3 ! 38.6 0.0 1.9e-12 1.3e-09 18 77 .] 146 203 .. 143 203 .. 0.96 4 ! 40.2 0.0 6.1e-13 4.1e-10 5 77 .] 213 283 .. 208 283 .. 0.96 5 ! 33.5 0.0 7.4e-11 5e-08 5 74 .. 293 360 .. 289 362 .. 0.95 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 5.1e-06 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ e l+ +e+ l++ae+++ d ++ a++ Lg +y ++ +A+e+++ +l+ia++ FUN_000345-T1 26 NFREVLDKHENQLNIAEKAG--DPAEEGKAYFHLGNTYKSHSNFPKAIECYKNSLNIARE 83 555667779999*******4..44579******************************986 PP == domain 2 score: 50.7 bits; conditional E-value: 3.1e-16 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl++++ l ++ +A+e++ek l +a+++ +d+ + a++nLg+++ d+ +A+e++e++l+ia++ FUN_000345-T1 93 AYFNLGSAYKLLSDFPKAIECYEKILSIARET--GDRATEGDAYFNLGIAHDSNRDFPKAIECYEKSLNIARE 163 788*****************************..99**********************************986 PP == domain 3 score: 38.6 bits; conditional E-value: 1.9e-12 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ +A+e++ek+l++a+++ +d+ + a +nLg++y d+ A e++e++l+ia+k FUN_000345-T1 146 DFPKAIECYEKSLNIAREA--GDWAREGKANFNLGIAYDSHSDFPRATECYEKSLNIARK 203 899****************..9***********************************996 PP == domain 4 score: 40.2 bits; conditional E-value: 6.1e-13 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+ +++ ++ +A+e+++k+l++a+++ +++ + a++nL ++y+ d+ +A+++++ +l ia++ FUN_000345-T1 213 AYFNLGIAYHSHSDFPKAIECYKKSLNIAREA--GNRVREGKAYFNLWIAYHSHSDFPKAIKCYQMSLSIARE 283 788*****************************..99**********************************986 PP == domain 5 score: 33.5 bits; conditional E-value: 7.4e-11 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 ++ nl+ +++ ++ +A+e++ k+l++a+++ +d+ ++++a + L ++y+alg++ +A e+ e+ l+i FUN_000345-T1 293 VYFNLGIAYHSHSDFPNAIECYGKSLNIAREA--GDRFGVSRAIHYLVICYSALGEFSQAAEYREEYLKI 360 6779****************************..999****************************99987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.1 8.5e-08 5.7e-05 2 30 .. 52 80 .. 51 83 .. 0.92 2 ! 30.8 0.2 3.5e-10 2.3e-07 2 31 .. 92 121 .. 92 123 .. 0.94 3 ! 27.4 0.0 4.3e-09 2.9e-06 2 31 .. 132 161 .. 131 163 .. 0.93 4 ! 15.7 0.0 2e-05 0.013 3 31 .. 173 201 .. 171 203 .. 0.90 5 ! 28.7 0.1 1.6e-09 1.1e-06 2 31 .. 212 241 .. 211 243 .. 0.93 6 ! 14.0 0.0 7.2e-05 0.049 2 31 .. 252 281 .. 251 283 .. 0.88 7 ! 22.0 0.0 2.1e-07 0.00014 2 30 .. 292 320 .. 291 323 .. 0.92 8 ? 2.9 0.2 0.23 1.6e+02 10 23 .. 340 353 .. 339 360 .. 0.90 9 ? 1.9 0.0 0.48 3.2e+02 20 29 .. 393 402 .. 391 403 .. 0.91 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 8.5e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka++ lGn+y + ++ +A+e+y+ L + FUN_000345-T1 52 KAYFHLGNTYKSHSNFPKAIECYKNSLNI 80 79**********************99976 PP == domain 2 score: 30.8 bits; conditional E-value: 3.5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka++nlG ay l ++ +A+e+yek L++ FUN_000345-T1 92 KAYFNLGSAYKLLSDFPKAIECYEKILSIA 121 79*************************986 PP == domain 3 score: 27.4 bits; conditional E-value: 4.3e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG a+ ++ ++ +A+e+yek L + FUN_000345-T1 132 DAYFNLGIAHDSNRDFPKAIECYEKSLNIA 161 79************************9775 PP == domain 4 score: 15.7 bits; conditional E-value: 2e-05 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a +nlG ay + ++ A e+yek L + FUN_000345-T1 173 ANFNLGIAYDSHSDFPRATECYEKSLNIA 201 669**********************9775 PP == domain 5 score: 28.7 bits; conditional E-value: 1.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG ay++ ++ +A+e+y+k L + FUN_000345-T1 212 DAYFNLGIAYHSHSDFPKAIECYKKSLNIA 241 79************************9775 PP == domain 6 score: 14.0 bits; conditional E-value: 7.2e-05 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka++nl ay++ ++ +A+++y+ L++ FUN_000345-T1 252 KAYFNLWIAYHSHSDFPKAIKCYQMSLSIA 281 678888889******************986 PP == domain 7 score: 22.0 bits; conditional E-value: 2.1e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ++++nlG ay++ ++ A+e+y k L + FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAIECYGKSLNI 320 68***********************9977 PP == domain 8 score: 2.9 bits; conditional E-value: 0.23 TPR_1 10 ayfklgkydeAley 23 +y +lg++ +A ey FUN_000345-T1 340 CYSALGEFSQAAEY 353 9**********998 PP == domain 9 score: 1.9 bits; conditional E-value: 0.48 TPR_1 20 AleyyekALe 29 Ale+y kAL+ FUN_000345-T1 393 ALEAYTKALT 402 9*******95 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 1.1e-05 0.0071 2 32 .. 52 82 .. 51 84 .. 0.93 2 ! 22.6 0.1 1.6e-07 0.00011 2 31 .. 92 121 .. 91 124 .. 0.93 3 ! 23.6 0.0 7.3e-08 4.9e-05 2 32 .. 132 162 .. 131 164 .. 0.93 4 ! 14.4 0.0 6.6e-05 0.045 2 32 .. 172 202 .. 171 204 .. 0.92 5 ! 22.0 0.1 2.4e-07 0.00016 2 32 .. 212 242 .. 211 244 .. 0.93 6 ? 6.4 0.0 0.024 16 4 32 .. 254 282 .. 251 284 .. 0.82 7 ! 16.4 0.0 1.5e-05 0.01 2 32 .. 292 322 .. 291 324 .. 0.92 8 ? 1.1 0.1 1.2 8.1e+02 10 26 .. 340 356 .. 335 362 .. 0.83 9 ? -0.0 0.0 2.8 1.9e+03 20 28 .. 393 401 .. 391 404 .. 0.88 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1.1e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++ lG+ y ++ +A+e+y+ +l ++ FUN_000345-T1 52 KAYFHLGNTYKSHSNFPKAIECYKNSLNIAR 82 79************************99875 PP == domain 2 score: 22.6 bits; conditional E-value: 1.6e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlG ay l d+ +A+e+yek l+++ FUN_000345-T1 92 KAYFNLGSAYKLLSDFPKAIECYEKILSIA 121 79*************************987 PP == domain 3 score: 23.6 bits; conditional E-value: 7.3e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG a+ + d+ +A+e+yek+l ++ FUN_000345-T1 132 DAYFNLGIAHDSNRDFPKAIECYEKSLNIAR 162 69*************************9875 PP == domain 4 score: 14.4 bits; conditional E-value: 6.6e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a +nlG ay d+ +A e+yek+l ++ FUN_000345-T1 172 KANFNLGIAYDSHSDFPRATECYEKSLNIAR 202 688************************9875 PP == domain 5 score: 22.0 bits; conditional E-value: 2.4e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++nlG ay d+ +A+e+y+k+l ++ FUN_000345-T1 212 DAYFNLGIAYHSHSDFPKAIECYKKSLNIAR 242 69*************************9875 PP == domain 6 score: 6.4 bits; conditional E-value: 0.024 TPR_2 4 lynlGlayyklgdyeeAleayekAleldP 32 ++nl ay d+ +A+++y+ +l+++ FUN_000345-T1 254 YFNLWIAYHSHSDFPKAIKCYQMSLSIAR 282 555557899999**********9999875 PP == domain 7 score: 16.4 bits; conditional E-value: 1.5e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 ++++nlG ay d+ A+e+y k+l ++ FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAIECYGKSLNIAR 322 58*************************9875 PP == domain 8 score: 1.1 bits; conditional E-value: 1.2 TPR_2 10 ayyklgdyeeAleayek 26 +y +lg++ +A+e+ e+ FUN_000345-T1 340 CYSALGEFSQAAEYREE 356 899*********99555 PP == domain 9 score: -0.0 bits; conditional E-value: 2.8 TPR_2 20 AleayekAl 28 Aleay kAl FUN_000345-T1 393 ALEAYTKAL 401 9*******9 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.16 1.1e+02 13 35 .. 25 47 .. 25 48 .. 0.93 2 ! 11.6 0.0 0.00051 0.34 1 35 [. 53 87 .. 53 88 .. 0.93 3 ! 19.8 0.0 1.2e-06 0.00081 1 36 [] 93 128 .. 93 128 .. 0.96 4 ! 15.6 0.0 2.7e-05 0.018 1 34 [. 133 166 .. 133 166 .. 0.94 5 ! 10.6 0.0 0.001 0.7 4 36 .] 176 208 .. 175 208 .. 0.95 6 ! 14.8 0.0 4.9e-05 0.033 1 35 [. 213 247 .. 213 248 .. 0.94 7 ? 6.3 0.0 0.025 17 2 34 .. 254 286 .. 253 286 .. 0.87 8 ! 11.3 0.0 0.00064 0.43 2 35 .. 294 327 .. 293 328 .. 0.95 9 ? 5.1 0.0 0.064 43 6 26 .. 338 358 .. 333 367 .. 0.81 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.16 TPR_7 13 GdydeAirlyerlLalakdpedr 35 G+++e ++ +e++L +a++ +d+ FUN_000345-T1 25 GNFREVLDKHENQLNIAEKAGDP 47 899****************9998 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00051 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ L+++y + ++ +Ai++y++ L +a++ +d+ FUN_000345-T1 53 AYFHLGNTYKSHSNFPKAIECYKNSLNIAREAGDQ 87 6789**************************99986 PP == domain 3 score: 19.8 bits; conditional E-value: 1.2e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+ +L+++y l d+ +Ai++ye+ L++a++ +dr+ FUN_000345-T1 93 AYFNLGSAYKLLSDFPKAIECYEKILSIARETGDRA 128 789******************************995 PP == domain 4 score: 15.6 bits; conditional E-value: 2.7e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+ +L+ ++ + +d+ +Ai++ye+ L +a++ +d FUN_000345-T1 133 AYFNLGIAHDSNRDFPKAIECYEKSLNIAREAGD 166 789*************************998776 PP == domain 5 score: 10.6 bits; conditional E-value: 0.001 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedre 36 +L+ +y + d+ +A ++ye+ L +a++ +dr+ FUN_000345-T1 176 NLGIAYDSHSDFPRATECYEKSLNIARKAGDRA 208 9****************************9985 PP == domain 6 score: 14.8 bits; conditional E-value: 4.9e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y++ d+ +Ai++y++ L +a++ ++r FUN_000345-T1 213 AYFNLGIAYHSHSDFPKAIECYKKSLNIAREAGNR 247 789***************************99887 PP == domain 7 score: 6.3 bits; conditional E-value: 0.025 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdped 34 + +L +y++ d+ +Ai++y+ L++a++ +d FUN_000345-T1 254 YFNLWIAYHSHSDFPKAIKCYQMSLSIAREAGD 286 66777899999****************998776 PP == domain 8 score: 11.3 bits; conditional E-value: 0.00064 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L+ +y++ d+ +Ai++y + L +a++ +dr FUN_000345-T1 294 YFNLGIAYHSHSDFPNAIECYGKSLNIAREAGDR 327 579***************************9997 PP == domain 9 score: 5.1 bits; conditional E-value: 0.064 TPR_7 6 ariyrklGdydeAirlyerlL 26 +y++lG++ +A+++ e+ L FUN_000345-T1 338 VICYSALGEFSQAAEYREEYL 358 568*************99855 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.0 0.00057 0.39 2 32 .. 52 82 .. 51 83 .. 0.94 2 ! 23.1 0.2 1.1e-07 7.5e-05 2 33 .. 92 123 .. 91 124 .. 0.95 3 ! 16.9 0.0 1.1e-05 0.0074 2 32 .. 132 162 .. 131 163 .. 0.95 4 ? 6.8 0.0 0.019 13 2 32 .. 172 202 .. 171 203 .. 0.93 5 ! 14.6 0.0 5.8e-05 0.039 2 32 .. 212 242 .. 211 243 .. 0.95 6 ? -1.5 0.0 8.3 5.6e+03 11 32 .. 261 282 .. 252 283 .. 0.72 7 ! 10.3 0.0 0.0014 0.91 2 32 .. 292 322 .. 291 323 .. 0.94 8 ? 0.4 0.2 2.2 1.5e+03 10 29 .. 340 359 .. 337 360 .. 0.86 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00057 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay++lG++y++ ++ +A+e+y+ +l +++ FUN_000345-T1 52 KAYFHLGNTYKSHSNFPKAIECYKNSLNIAR 82 79***********************999986 PP == domain 2 score: 23.1 bits; conditional E-value: 1.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldpd 33 +ay+nlG++y+ l d+ +A+e+yek l+++++ FUN_000345-T1 92 KAYFNLGSAYKLLSDFPKAIECYEKILSIARE 123 79***************************986 PP == domain 3 score: 16.9 bits; conditional E-value: 1.1e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG ++ + d+ +A+e+yek+l +++ FUN_000345-T1 132 DAYFNLGIAHDSNRDFPKAIECYEKSLNIAR 162 69*************************9987 PP == domain 4 score: 6.8 bits; conditional E-value: 0.019 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +a +nlG +y + d+ A e+yek+l +++ FUN_000345-T1 172 KANFNLGIAYDSHSDFPRATECYEKSLNIAR 202 6899***********************9987 PP == domain 5 score: 14.6 bits; conditional E-value: 5.8e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG +y++ d+ +A+e+y+k+l +++ FUN_000345-T1 212 DAYFNLGIAYHSHSDFPKAIECYKKSLNIAR 242 69*************************9987 PP == domain 6 score: -1.5 bits; conditional E-value: 8.3 TPR_8 11 ylklgdyeeAkeyyekaleldp 32 y++ d+ +A+++y+ +l++++ FUN_000345-T1 261 YHSHSDFPKAIKCYQMSLSIAR 282 5555566689****98888876 PP == domain 7 score: 10.3 bits; conditional E-value: 0.0014 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++y+nlG +y++ d+ +A+e+y k+l +++ FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAIECYGKSLNIAR 322 68*************************9986 PP == domain 8 score: 0.4 bits; conditional E-value: 2.2 TPR_8 10 iylklgdyeeAkeyyekale 29 +y+ lg++ +A ey e+ l+ FUN_000345-T1 340 CYSALGEFSQAAEYREEYLK 359 69***********9887776 PP >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.6 0.8 1.5e-19 1e-16 1 142 [] 788 948 .. 788 948 .. 0.86 Alignments for each domain: == domain 1 score: 61.6 bits; conditional E-value: 1.5e-19 COR-A 1 Pkswlevreelee.kkseknyisleeyreicke.nglkeeeeqdrllkfLhdlGvllyfqddeelkdlviLkpeWlteavykvlds.......... 84 P +wl+++++l+ ++ +++i++e+ +i++e +++ +++e ++++fLhd l++f+d el++lv+L+p+Wl+++ +v++ FUN_000345-T1 788 PIKWLKYERALQViLAEGHKCITIEHAEQIASEiCQIGDHQEFVTMIDFLHDQRILIHFDDTVELNKLVVLDPQWLIDVFKAVITVkpfhkhergf 883 89***********99999************97548**************************99**********************98888777777 PP COR-A 85 ...kevlkkkGllkeedlkkiwkek.ypaeehdellrlmekfel.cyelek..eeedtylvpqlL 142 l+++G+l+e+ l++ w + ++++ ++l+ +mekf l cy ++ +++ylvp++L FUN_000345-T1 884 kdmWLKLERDGILDEKLLRHAWGQIvEEHHTFESLIAIMEKFSLlCYWSSSdePCRKKYLVPSML 948 4322234455************997666777799********9548887775434689****987 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.6 1.3 3.8e-09 2.5e-06 61 180 .. 37 156 .. 25 165 .. 0.85 2 ! 34.8 0.7 2.5e-11 1.7e-08 44 180 .. 100 236 .. 99 236 .. 0.96 3 ! 27.4 0.7 4.3e-09 2.9e-06 46 180 .. 182 316 .. 177 357 .. 0.93 Alignments for each domain: == domain 1 score: 27.6 bits; conditional E-value: 3.8e-09 SNAP 61 aAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealan 155 ++ ek++++ e ++ay+ + yk+ + +A+e+++++ +i e+g ++ k +++++ y+ +d+ kAie+Ye+ + ++ + a+ FUN_000345-T1 37 QLNIAEKAGDPAEEGKAYFHLGNTYKSHsNFPKAIECYKNSLNIAREAGDQTTEQKAYFNLGSAYKLL-SDFPKAIECYEKILSIARETGDRATEG 131 55678889999999999999999999874667999999999999999999999999999999999976.999999999999999999999999999 PP SNAP 156 kcllkvAdlsaelekyekAieiyek 180 ++ ++ + ++++++kAie yek FUN_000345-T1 132 DAYFNLGIAHDSNRDFPKAIECYEK 156 9999999999999999999999997 PP == domain 2 score: 34.8 bits; conditional E-value: 2.5e-11 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 aykl ++ +A e+++k+ ++ ++++++ ++ay++ + ++ d +A+e++ek+ +i e+g r +k +++++ y++ +d+ +A+e+Y FUN_000345-T1 100 AYKLLSDFPKAIECYEKILSIARETGDRATEGDAYFNLGIAHDSNrDFPKAIECYEKSLNIAREAGDWAREGKANFNLGIAYDSH-SDFPRATECY 194 7************************************999888775788************************************.********** PP SNAP 139 eqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e++ ++ ++ + a+ ++ ++ + ++ +++kAie y+k FUN_000345-T1 195 EKSLNIARKAGDRATEGDAYFNLGIAYHSHSDFPKAIECYKK 236 ****************************************86 PP == domain 3 score: 27.4 bits; conditional E-value: 4.3e-09 SNAP 46 klakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeq 140 + ++ +A e+++k ++ +k++++ ++ay++ +y++ d +A+e+++k+ +i e+g+ r +k ++++ y + +d+ kAi++Y+ FUN_000345-T1 182 DSHSDFPRATECYEKSLNIARKAGDRATEGDAYFNLGIAYHSHsDFPKAIECYKKSLNIAREAGNRVREGKAYFNLWIAYHSH-SDFPKAIKCYQM 276 55677899****************************99999875788**********************************99.************ PP SNAP 141 AadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + + ++ + ++ + ++ ++ + ++ ++++Aie y k FUN_000345-T1 277 SLSIAREAGDWSTEEDVYFNLGIAYHSHSDFPNAIECYGK 316 **********************9999**********9965 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.1 6.3e-09 4.3e-06 2 73 .. 413 483 .. 412 506 .. 0.77 2 ! 26.0 0.0 1.8e-08 1.2e-05 48 90 .. 601 644 .. 573 671 .. 0.78 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 6.3e-09 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslh 73 ++l+G+++ GKtsl k + +f+++e+st+g+d+ + ++ ++++ ++ +k+ n D+aG + + + FUN_000345-T1 413 IMLIGQERSGKTSLKKSLQGLQFNPDEDSTVGIDVDPSYFKVTTEIWKT-GKKDQAANNKDMAGSYEHHVAR 483 89*********************************99876444444333.3455566777777776666544 PP == domain 2 score: 26.0 bits; conditional E-value: 1.8e-08 Roc 48 endkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.sr 90 ++ + +i +WD+aG+ ++++h+l+++++a+++lv+d sr FUN_000345-T1 601 DKMGSEDDIYSVLWDFAGESVYYETHQLFLTSRAIYLLVYDlSR 644 3333445677789****************************644 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.064 43 7 35 .. 56 84 .. 53 84 .. 0.93 2 ? 6.9 0.0 0.014 9.5 7 35 .. 96 124 .. 93 124 .. 0.95 3 ! 9.2 0.0 0.0027 1.8 7 35 .. 136 164 .. 132 164 .. 0.93 4 ! 8.5 0.0 0.0044 3 7 35 .. 176 204 .. 176 204 .. 0.96 5 ! 7.4 0.0 0.0096 6.5 7 35 .. 216 244 .. 212 244 .. 0.93 6 ? 4.6 0.0 0.072 49 7 35 .. 296 324 .. 294 324 .. 0.96 7 ? -1.2 0.0 4.9 3.3e+03 4 24 .. 333 353 .. 330 359 .. 0.84 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.064 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 +L+n++ + ++ A e ++ +l i++++ FUN_000345-T1 56 HLGNTYKSHSNFPKAIECYKNSLNIAREA 84 69**********************99985 PP == domain 2 score: 6.9 bits; conditional E-value: 0.014 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ + ++ A e +e+ l i++++ FUN_000345-T1 96 NLGSAYKLLSDFPKAIECYEKILSIARET 124 9************************9985 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0027 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ +++++ A e +e++l i++++ FUN_000345-T1 136 NLGIAHDSNRDFPKAIECYEKSLNIAREA 164 9************************9985 PP == domain 4 score: 8.5 bits; conditional E-value: 0.0044 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ + ++ +A e +e++l i++++ FUN_000345-T1 176 NLGIAYDSHSDFPRATECYEKSLNIARKA 204 9************************9985 PP == domain 5 score: 7.4 bits; conditional E-value: 0.0096 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ + ++ A e ++++l i++++ FUN_000345-T1 216 NLGIAYHSHSDFPKAIECYKKSLNIAREA 244 9************************9985 PP == domain 6 score: 4.6 bits; conditional E-value: 0.072 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ a+ + ++ A e + ++l i++++ FUN_000345-T1 296 NLGIAYHSHSDFPNAIECYGKSLNIAREA 324 9************************9985 PP == domain 7 score: -1.2 bits; conditional E-value: 4.9 TPR_10 4 slnnLanalraqgryeeAeel 24 +++ L ++a+g++ A e+ FUN_000345-T1 333 AIHYLVICYSALGEFSQAAEY 353 6788888899******99987 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.14 93 14 34 .] 52 72 .. 49 72 .. 0.91 2 ? 6.5 0.0 0.025 17 14 34 .] 92 112 .. 88 112 .. 0.91 3 ? 6.6 0.0 0.022 15 13 34 .] 131 152 .. 128 152 .. 0.91 4 ? 0.5 0.0 2.1 1.4e+03 14 32 .. 172 190 .. 170 192 .. 0.85 5 ! 9.2 0.0 0.0035 2.3 13 34 .] 211 232 .. 208 232 .. 0.90 6 ? 4.7 0.0 0.091 61 14 33 .. 292 311 .. 289 312 .. 0.85 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.14 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay+ L+++++ ++ +A++ FUN_000345-T1 52 KAYFHLGNTYKSHSNFPKAIE 72 79*************999985 PP == domain 2 score: 6.5 bits; conditional E-value: 0.025 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay+nL+ +++ + ++ +A++ FUN_000345-T1 92 KAYFNLGSAYKLLSDFPKAIE 112 79***************9985 PP == domain 3 score: 6.6 bits; conditional E-value: 0.022 TPR_17 13 adayynLArlllnnGqleeAlq 34 day+nL++++ n ++ +A++ FUN_000345-T1 131 GDAYFNLGIAHDSNRDFPKAIE 152 69****************9985 PP == domain 4 score: 0.5 bits; conditional E-value: 2.1 TPR_17 14 dayynLArlllnnGqleeA 32 +a +nL++++ ++ +A FUN_000345-T1 172 KANFNLGIAYDSHSDFPRA 190 689*******999888777 PP == domain 5 score: 9.2 bits; conditional E-value: 0.0035 TPR_17 13 adayynLArlllnnGqleeAlq 34 day+nL+++++ ++ +A++ FUN_000345-T1 211 GDAYFNLGIAYHSHSDFPKAIE 232 69***************99985 PP == domain 6 score: 4.7 bits; conditional E-value: 0.091 TPR_17 14 dayynLArlllnnGqleeAl 33 d+y+nL+++++ ++ A+ FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAI 311 79*********999887776 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.1 0.001 0.68 1 39 [. 58 102 .. 58 105 .. 0.75 2 ? 4.5 0.0 0.059 40 1 19 [. 98 116 .. 98 121 .. 0.91 3 ? 1.3 0.0 0.59 4e+02 29 38 .. 132 141 .. 129 144 .. 0.90 4 ? 3.5 0.0 0.12 80 10 23 .. 147 160 .. 146 164 .. 0.88 5 ? -2.5 0.0 9.1 6.1e+03 30 38 .. 173 181 .. 172 182 .. 0.89 6 ? 5.4 0.3 0.03 20 29 40 .. 212 223 .. 211 225 .. 0.91 7 ! 8.6 0.1 0.003 2 3 23 .. 220 240 .. 218 243 .. 0.90 8 ! 8.0 0.0 0.0047 3.2 3 40 .. 260 303 .. 260 305 .. 0.73 9 ? 5.3 0.0 0.035 23 3 23 .. 300 320 .. 298 323 .. 0.90 10 ? -1.3 0.0 3.9 2.6e+03 12 21 .. 392 401 .. 391 402 .. 0.88 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.001 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayy 39 G+ y + ++++Aie+Yk+ l++ + + ay+nLG ay FUN_000345-T1 58 GNTYKSHSNFPKAIECYKNSLNIAREAGDqtteqkAYFNLGSAYK 102 99999*****************96655333333337888888775 PP == domain 2 score: 4.5 bits; conditional E-value: 0.059 TPR_11 1 GdayyeqGkyeeAieaYkk 19 G ay + ++++Aie+Y+k FUN_000345-T1 98 GSAYKLLSDFPKAIECYEK 116 78999999*********98 PP == domain 3 score: 1.3 bits; conditional E-value: 0.59 TPR_11 29 eayynLGlay 38 +ay+nLG a+ FUN_000345-T1 132 DAYFNLGIAH 141 79*****997 PP == domain 4 score: 3.5 bits; conditional E-value: 0.12 TPR_11 10 yeeAieaYkkAlkl 23 +++Aie+Y+k l++ FUN_000345-T1 147 FPKAIECYEKSLNI 160 789*******9987 PP == domain 5 score: -2.5 bits; conditional E-value: 9.1 TPR_11 30 ayynLGlay 38 a +nLG ay FUN_000345-T1 173 ANFNLGIAY 181 789*****9 PP == domain 6 score: 5.4 bits; conditional E-value: 0.03 TPR_11 29 eayynLGlayyk 40 +ay+nLG ay+ FUN_000345-T1 212 DAYFNLGIAYHS 223 79********95 PP == domain 7 score: 8.6 bits; conditional E-value: 0.003 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay++ ++++Aie+Ykk l++ FUN_000345-T1 220 AYHSHSDFPKAIECYKKSLNI 240 899999***********9987 PP == domain 8 score: 8.0 bits; conditional E-value: 0.0047 TPR_11 3 ayyeqGkyeeAieaYkkAlkldPdn......aeayynLGlayyk 40 ay++ ++++Ai++Y+ l + + ++y+nLG ay+ FUN_000345-T1 260 AYHSHSDFPKAIKCYQMSLSIAREAgdwsteEDVYFNLGIAYHS 303 5777788888888888888887543222222899********95 PP == domain 9 score: 5.3 bits; conditional E-value: 0.035 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ay++ ++++Aie+Y k l++ FUN_000345-T1 300 AYHSHSDFPNAIECYGKSLNI 320 899999***********9987 PP == domain 10 score: -1.3 bits; conditional E-value: 3.9 TPR_11 12 eAieaYkkAl 21 +A+eaY kAl FUN_000345-T1 392 GALEAYTKAL 401 7********8 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 1 6.7e+02 2 24 .. 53 75 .. 52 79 .. 0.90 2 ! 11.2 0.0 0.001 0.69 2 28 .. 93 119 .. 92 122 .. 0.94 3 ? 6.6 0.0 0.03 20 1 25 [. 132 156 .. 132 160 .. 0.93 4 ? 5.8 0.0 0.054 36 1 25 [. 212 236 .. 212 240 .. 0.92 5 ? 1.6 0.0 1.1 7.7e+02 1 25 [. 292 316 .. 292 319 .. 0.89 6 ? 0.6 0.0 2.5 1.7e+03 5 22 .. 336 353 .. 332 359 .. 0.83 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 1 TPR_6 2 AllklalsylelgdkdeAkaalq 24 A+++l+ y+ ++ +A++ ++ FUN_000345-T1 53 AYFHLGNTYKSHSNFPKAIECYK 75 99*********77*******997 PP == domain 2 score: 11.2 bits; conditional E-value: 0.001 TPR_6 2 AllklalsylelgdkdeAkaalqrlik 28 A+++l+ +y+ l d+ +A++ ++++++ FUN_000345-T1 93 AYFNLGSAYKLLSDFPKAIECYEKILS 119 99*********99***********985 PP == domain 3 score: 6.6 bits; conditional E-value: 0.03 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+++l+ ++ d+ +A++ +++ FUN_000345-T1 132 DAYFNLGIAHDSNRDFPKAIECYEK 156 8***********88*********98 PP == domain 4 score: 5.8 bits; conditional E-value: 0.054 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+++l+ +y d+ +A++ +++ FUN_000345-T1 212 DAYFNLGIAYHSHSDFPKAIECYKK 236 8***********77*********97 PP == domain 5 score: 1.6 bits; conditional E-value: 1.1 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++++l+ +y d+ +A++ + + FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAIECYGK 316 789*********77******99976 PP == domain 6 score: 0.6 bits; conditional E-value: 2.5 TPR_6 5 klalsylelgdkdeAkaa 22 +l +y +lg++ +A+++ FUN_000345-T1 336 YLVICYSALGEFSQAAEY 353 7778***********987 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.6 0.0 0.00013 0.086 38 154 .. 49 163 .. 22 177 .. 0.80 2 ! 18.8 0.0 1.7e-06 0.0011 15 191 .. 185 361 .. 177 381 .. 0.87 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00013 TPR_MalT 38 artlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLly 133 + + a++ lG ++ ++ +A + ++ +ar+a++ + + a+ ++ + ++ +A+e y+++l a+e++ +a + g ++ l+ + FUN_000345-T1 49 EEGKAYFHLGNTYKSHSNFPKAIECYKNSLNIAREAGDQTTEQKAYFNLGSAYKLLSDFPKAIECYEKILSIARETGDRA--TEGDAYFNLGIAHD 142 458899*********************************9999999999999999999******************9997..55566666666666 PP TPR_MalT 134 EwndLeeAeqhlqqgiqlgrq 154 d+ +A ++ +++++++r+ FUN_000345-T1 143 SNRDFPKAIECYEKSLNIARE 163 666666666666666666665 PP == domain 2 score: 18.8 bits; conditional E-value: 1.7e-06 TPR_MalT 15 geaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 ++++a e ++ L++ ++ d ++ + a+++lG a++ d+ +A + +++ +ar+a++ + a+ ++ + ++ +A++ yq l FUN_000345-T1 185 SDFPRATECYEKSLNIARKAgDRATEGDAYFNLGIAYHSHSDFPKAIECYKKSLNIAREAGNRVREGKAYFNLWIAYHSHSDFPKAIKCYQMSLSI 280 5677777777778888777535567799******************************************************************** PP TPR_MalT 110 aqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerla 191 a+e++ ++ + ++ l+ ++ d+ +A ++ ++++++r++ +++ + +a l+ a Ge ++A ++ ++ +++ FUN_000345-T1 281 AREAGDW--STEEDVYFNLGIAYHSHSDFPNAIECYGKSLNIAREAgDRFGVSRAIHYLVICYSALGEFSQAAEYREEYLKIV 361 ***9988..588999999***************************96667777898999999999********9987766655 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.4 2.7e+02 16 62 .. 31 77 .. 27 85 .. 0.84 2 ! 18.1 0.0 3.6e-06 0.0024 18 139 .. 73 197 .. 67 203 .. 0.84 3 ! 12.4 0.1 0.0002 0.13 37 145 .. 212 323 .. 194 346 .. 0.81 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.4 RPN7 16 leeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayera 62 l++ e++l+ a++ e +a+ l++ y ++ ++ +A+++y+ FUN_000345-T1 31 LDKHENQLNIAEKAGDPAEEGKAYFHLGNTYKSHSNFPKAIECYKNS 77 566677888888888888888999********************975 PP == domain 2 score: 18.1 bits; conditional E-value: 3.6e-06 RPN7 18 eLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghkidlllnlirvgif...fndwalvskylekaksliekggdwe 110 ++ l+ a+e ++ ++a+ +l+ y d+ +A+++ye+++ + +g + + ++gi+ +d+ ++ + ek ++ ++gdw FUN_000345-T1 73 CYKNSLNIAREAGDQTTEQKAYFNLGSAYKLLSDFPKAIECYEKILSIARETGDRATEGDAYFNLGIAhdsNRDFPKAIECYEKSLNIAREAGDWA 168 56677888888888888899*************************9999999988866666666666611157777778888888899999***** PP RPN7 111 rrnrlkvyeGlaalairkfkeAaklllds 139 r+ + + G+a+ + +f +A+++ +s FUN_000345-T1 169 REGKANFNLGIAYDSHSDFPRATECYEKS 197 ***********************997665 PP == domain 3 score: 12.4 bits; conditional E-value: 0.0002 RPN7 37 raledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekak...sliekggdwerrnrlkvyeGlaalairkf 129 +a+ +l+ y+++ d+ +A+++y++ ++ + +g+ + + ++ i+++ ++ k ++ + s+ ++gdw+++ + G+a+ + +f FUN_000345-T1 212 DAYFNLGIAYHSHSDFPKAIECYKKSLNIAREAGNRVREGKAYFNLWIAYHSHSDFPKAIKCYQmslSIAREAGDWSTEEDVYFNLGIAYHSHSDF 307 678899999*****************************999999999999877777777765551115667799********************** PP RPN7 130 keAakllldslstfts 145 A ++ +sl + FUN_000345-T1 308 PNAIECYGKSLNIARE 323 ****999988766554 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 4.1 2.8e+03 28 53 .. 48 73 .. 35 88 .. 0.60 2 ? 4.5 0.0 0.11 72 30 58 .. 90 118 .. 55 127 .. 0.70 3 ! 10.4 0.0 0.0015 1 4 58 .. 98 158 .. 95 166 .. 0.79 4 ! 8.0 0.0 0.0082 5.5 2 57 .. 136 197 .. 135 207 .. 0.80 5 ! 10.5 0.0 0.0014 0.94 3 58 .. 177 238 .. 175 246 .. 0.74 6 ? 1.2 0.0 1.2 7.8e+02 32 52 .. 292 312 .. 263 318 .. 0.85 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 4.1 TPR_16 28 PeaaaAllglGlallrqgrlaeAaaa 53 e A++ lG + ++++A++ FUN_000345-T1 48 AEEGKAYFHLGNTYKSHSNFPKAIEC 73 55555555555555555555555543 PP == domain 2 score: 4.5 bits; conditional E-value: 0.11 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraal 58 A+++lG a+ + ++++A++ y+++l FUN_000345-T1 90 EQKAYFNLGSAYKLLSDFPKAIECYEKIL 118 4579******************9999987 PP == domain 3 score: 10.4 bits; conditional E-value: 0.0015 TPR_16 4 araalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 + a+ + d++ A++++e l +A+++lG a+ ++++++A++ y++ l FUN_000345-T1 98 GSAYKLLSDFPKAIECYEKILSIAretgdrATEGDAYFNLGIAHDSNRDFPKAIECYEKSL 158 55666678899999999666655557888877899*******************9998876 PP == domain 4 score: 8.0 bits; conditional E-value: 0.0082 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraa 57 l+ a+ ++d++ A++++e l + A ++lG a+ ++++A + y++ FUN_000345-T1 136 NLGIAHDSNRDFPKAIECYEKSLNIAreagdwAREGKANFNLGIAYDSHSDFPRATECYEKS 197 68999999**********98765333346799999************999999997776665 PP == domain 5 score: 10.5 bits; conditional E-value: 0.0014 TPR_16 3 laraalaagdyddAaaalea....alrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a+ + d+++A +++e a++++ +A+++lG a++ ++++A++ y++ l FUN_000345-T1 177 LGIAYDSHSDFPRATECYEKslniARKAGdrATEGDAYFNLGIAYHSHSDFPKAIECYKKSL 238 677777777777777666541111555558877899*******************9998876 PP == domain 6 score: 1.2 bits; conditional E-value: 1.2 TPR_16 32 aAllglGlallrqgrlaeAaa 52 + +++lG a++ +++ A++ FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAIE 312 578999****99999999996 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.0011 0.71 10 75 .. 63 128 .. 54 134 .. 0.93 2 ? 4.1 0.0 0.1 68 13 74 .. 106 167 .. 105 187 .. 0.82 3 ? 1.7 0.0 0.58 3.9e+02 56 74 .. 149 167 .. 134 216 .. 0.58 4 ? 6.3 0.0 0.022 15 8 75 .. 221 288 .. 214 292 .. 0.92 5 ? 2.9 0.0 0.25 1.7e+02 42 85 .. 295 338 .. 291 343 .. 0.86 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.0011 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 +++++++a+++ + ++ + ++++ q a +nl + + +++ +A++ e ++Are +D a FUN_000345-T1 63 SHSNFPKAIECYKNSLNIAREAGDQTTEQKAYFNLGSAYKLLSDFPKAIECYEKILSIARETGDRA 128 578999*********************************************************987 PP == domain 2 score: 4.1 bits; conditional E-value: 0.1 ANAPC5 13 dYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 d+++a+++ ++ ++ ++ ++ + a +nl i h + + +A++ e + ++Are +D FUN_000345-T1 106 DFPKAIECYEKILSIARETGDRATEGDAYFNLGIAHDSNRDFPKAIECYEKSLNIAREAGDW 167 67777777777777777777777777889999999999999999999999999999999885 PP == domain 3 score: 1.7 bits; conditional E-value: 0.58 ANAPC5 56 eAvkaieeaiklArenkDt 74 +A++ e + ++Are +D FUN_000345-T1 149 KAIECYEKSLNIAREAGDW 167 4444444444444444432 PP == domain 4 score: 6.3 bits; conditional E-value: 0.022 ANAPC5 8 alrakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDta 75 ++++d+++a+++ + ++ + ++ + a +nl i +++ ++ +A+k + + ++Are +D + FUN_000345-T1 221 YHSHSDFPKAIECYKKSLNIAREAGNRVREGKAYFNLWIAYHSHSDFPKAIKCYQMSLSIAREAGDWS 288 5788999*********************99**********************************9965 PP == domain 5 score: 2.9 bits; conditional E-value: 0.25 ANAPC5 42 lnlailhadfghneeAvkaieeaiklArenkDtacLnlalswll 85 +nl i +++ ++ +A++ + ++Are +D ++ a+++l+ FUN_000345-T1 295 FNLGIAYHSHSDFPNAIECYGKSLNIAREAGDRFGVSRAIHYLV 338 6777777888888899999999************9999999886 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.017 11 210 250 .. 36 76 .. 30 88 .. 0.75 2 ! 10.9 0.1 0.00026 0.17 205 250 .. 71 116 .. 49 121 .. 0.92 3 ! 10.4 0.0 0.00036 0.24 81 142 .. 95 157 .. 86 164 .. 0.88 4 ! 6.3 0.1 0.0064 4.3 87 142 .. 181 237 .. 167 259 .. 0.69 5 ? 2.5 0.0 0.094 63 205 251 .. 271 317 .. 260 323 .. 0.93 6 ? 0.1 0.0 0.48 3.2e+02 114 160 .. 446 492 .. 440 508 .. 0.83 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.017 TPR_IF140-IFT172 210 edlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 ++l+ a++ + +++ a +hl+ y ++ ++ +ai+ + + FUN_000345-T1 36 NQLNIAEKAGDPAEEGKAYFHLGNTYKSHSNFPKAIECYKN 76 455666666666777779******************97754 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00026 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 + Cy++ l+ a+e ++t ++ a + l+ y ++ +ai+ + + FUN_000345-T1 71 IECYKNSLNIAREAGDQTTEQKAYFNLGSAYKLLSDFPKAIECYEK 116 78****************************************9987 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00036 TPR_IF140-IFT172 81 lksckrydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 ++ + y ll+++ +a + ++k l++a++ dr ++y+n ++++d+ +ai+ yeks FUN_000345-T1 95 FNLGSAYKLLSDFPKAIECYEKILSIAREtGDRATEGDAYFNLGIAHDSNRDFPKAIECYEKS 157 555678********************97516*******************************8 PP == domain 4 score: 6.3 bits; conditional E-value: 0.0064 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 yd +++ +a++ ++k+l++a+k dr ++y+n ++ d+ +ai+ y+ks FUN_000345-T1 181 YDSHSDFPRATECYEKSLNIARKAgDRATEGDAYFNLGIAYHSHSDFPKAIECYKKS 237 666666666666666666666553366666666666666666666666666666665 PP == domain 5 score: 2.5 bits; conditional E-value: 0.094 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 ++Cy+ l+ a+e + + ++ + l+ y ++ ++ +ai+ ++++ FUN_000345-T1 271 IKCYQMSLSIAREAGDWSTEEDVYFNLGIAYHSHSDFPNAIECYGKS 317 78******************************************986 PP == domain 6 score: 0.1 bits; conditional E-value: 0.48 TPR_IF140-IFT172 114 hlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaL 160 ++ y++ + ++ ++g+ ++a+++ + + +++v r++f++ ++ FUN_000345-T1 446 DVDPSYFKVTTEIWKTGKKDQAANNKDMAGSYEHHVARVVFENLREQ 492 56668999999999****************************97643 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.02 13 144 212 .. 60 127 .. 51 132 .. 0.68 2 ? 1.8 0.0 0.33 2.2e+02 188 211 .. 143 166 .. 133 170 .. 0.88 3 ? 2.2 0.0 0.25 1.7e+02 188 212 .. 183 207 .. 173 212 .. 0.87 4 ? 5.6 0.0 0.023 15 141 211 .. 217 286 .. 212 294 .. 0.65 5 ? 3.4 0.0 0.11 72 145 211 .. 261 326 .. 253 332 .. 0.50 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.02 ComR_TPR 144 vllllkdyekleellkvlkeiidktqdf.qkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgde 212 ++ ++ ++ k e+ k + +i +++ d+ ++ ++ l y l df kA e+Y+k ++ a+ +gd FUN_000345-T1 60 TYKSHSNFPKAIECYKNSLNIAREAGDQtTEQKAYFNLGSAYKL--LSDFPKAIECYEKILSIARETGDR 127 44455555555555555556666665541445667777777777..899**********99999999996 PP == domain 2 score: 1.8 bits; conditional E-value: 0.33 ComR_TPR 188 vkkdfkkAkelYqkaimfakllgd 211 ++df kA e+Y+k++ a+ gd FUN_000345-T1 143 SNRDFPKAIECYEKSLNIAREAGD 166 6899**************998887 PP == domain 3 score: 2.2 bits; conditional E-value: 0.25 ComR_TPR 188 vkkdfkkAkelYqkaimfakllgde 212 + df +A e+Y+k++ a+ gd FUN_000345-T1 183 SHSDFPRATECYEKSLNIARKAGDR 207 5789****************99996 PP == domain 4 score: 5.6 bits; conditional E-value: 0.023 ComR_TPR 141 alavllllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 + ++ ++ d+ k e+ k++ +i +++ + + ++ w y + df kA ++Yq +++ a+ gd FUN_000345-T1 217 LGIAYHSHSDFPKAIECYKKSLNIAREAGNRVREGKAYFNLWIAYH-SHSDFPKAIKCYQMSLSIAREAGD 286 4455666666666666666666666666554444444444443333.5899***********999998888 PP == domain 5 score: 3.4 bits; conditional E-value: 0.11 ComR_TPR 145 llllkdyekleellkvlkeiidktqdfq.kkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 + ++ d+ k ++ +++ i +++ d + + +++ l y+ + df +A e+Y k++ a+ gd FUN_000345-T1 261 YHSHSDFPKAIKCYQMSLSIAREAGDWStEEDVYFNLGIAYHS--HSDFPNAIECYGKSLNIAREAGD 326 4444444444444444444444444433133344444444444..56666666666666666666665 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.047 32 3 65 .. 59 127 .. 57 131 .. 0.80 2 ? 4.3 0.0 0.09 60 4 64 .. 140 206 .. 137 209 .. 0.64 3 ? 3.0 0.0 0.22 1.5e+02 7 61 .. 183 243 .. 177 249 .. 0.75 4 ? 5.2 0.0 0.045 30 4 62 .. 260 324 .. 257 334 .. 0.70 5 ? -0.1 0.0 2.1 1.4e+03 37 57 .. 339 359 .. 339 373 .. 0.84 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.047 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 + y + ++++a++++ l + + + +++ G++y l ++ +A+++ e+ l++a + d+ FUN_000345-T1 59 NTYKSHSNFPKAIECYKNSLNIareagdQTTEQKAYFNLGSAYKLLSDFPKAIECYEKILSIARETGDR 127 667778888888888888888877766666666779999******************999998876665 PP == domain 2 score: 4.3 bits; conditional E-value: 0.09 TPR_9 4 iyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapd 64 ++ +++d+++a++++e l + ++ ++ G++y ++ +A+++ e+ l +a +a d FUN_000345-T1 140 AHDSNRDFPKAIECYEKSLNIareagdWAREGKANFNLGIAYDSHSDFPRATECYEKSLNIARKAGD 206 567899**********999994432222333344556666666666777777777777766666655 PP == domain 3 score: 3.0 bits; conditional E-value: 0.22 TPR_9 7 reedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapd 61 + d++ra +++e l + + + + +++ G++y+ ++ +A+++ ++ l +a + FUN_000345-T1 183 SHSDFPRATECYEKSLNIarkagdRATEGDAYFNLGIAYHSHSDFPKAIECYKKSLNIARE 243 6678888888888888887776666677778899999999999999999988877766655 PP == domain 4 score: 5.2 bits; conditional E-value: 0.045 TPR_9 4 iyireedleralavverllll..aPddpee....rrdrGllyaqlgcleaAladLeaylalapda 62 +y++ d+++a++++++ l + + d++ +++ G++y+ ++ A+++ + l +a +a FUN_000345-T1 260 AYHSHSDFPKAIKCYQMSLSIarEAGDWSTeedvYFNLGIAYHSHSDFPNAIECYGKSLNIAREA 324 689999*************9955444443222226777777777777777777766666655555 PP == domain 5 score: -0.1 bits; conditional E-value: 2.1 TPR_9 37 llyaqlgcleaAladLeayla 57 ++y lg +++A+++ e yl+ FUN_000345-T1 339 ICYSALGEFSQAAEYREEYLK 359 58999*********9999995 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.1 0.08 54 17 39 .. 64 86 .. 50 99 .. 0.80 2 ? 7.3 0.0 0.011 7.1 8 32 .. 135 159 .. 130 165 .. 0.89 3 ? 3.5 0.0 0.16 1.1e+02 8 33 .. 175 200 .. 169 213 .. 0.85 4 ? 3.1 0.0 0.22 1.5e+02 10 32 .. 217 239 .. 209 244 .. 0.83 5 ? -1.0 0.0 4.1 2.8e+03 18 31 .. 265 278 .. 259 289 .. 0.85 6 ? -0.5 0.0 2.9 1.9e+03 13 32 .. 300 319 .. 294 323 .. 0.80 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.08 MIT 17 agnyeeAlelYkealelLlqalk 39 n+ +A+e+Yk++l+ a + FUN_000345-T1 64 HSNFPKAIECYKNSLNIAREAGD 86 67999*********997666555 PP == domain 2 score: 7.3 bits; conditional E-value: 0.011 MIT 8 vkkAveeDnagnyeeAlelYkeale 32 ++ + D++ ++ +A+e+Y+++l+ FUN_000345-T1 135 FNLGIAHDSNRDFPKAIECYEKSLN 159 6778999***************997 PP == domain 3 score: 3.5 bits; conditional E-value: 0.16 MIT 8 vkkAveeDnagnyeeAlelYkealel 33 ++ + +D+ ++ A e+Y+++l+ FUN_000345-T1 175 FNLGIAYDSHSDFPRATECYEKSLNI 200 567899*****************985 PP == domain 4 score: 3.1 bits; conditional E-value: 0.22 MIT 10 kAveeDnagnyeeAlelYkeale 32 + + + ++ +A+e+Yk++l+ FUN_000345-T1 217 LGIAYHSHSDFPKAIECYKKSLN 239 566677788999********997 PP == domain 5 score: -1.0 bits; conditional E-value: 4.1 MIT 18 gnyeeAlelYkeal 31 ++ +A+++Y+ +l FUN_000345-T1 265 SDFPKAIKCYQMSL 278 68899*****9887 PP == domain 6 score: -0.5 bits; conditional E-value: 2.9 MIT 13 eeDnagnyeeAlelYkeale 32 + + ++ A+e+Y ++l+ FUN_000345-T1 300 AYHSHSDFPNAIECYGKSLN 319 556678899******99987 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.051 35 55 79 .. 23 47 .. 13 48 .. 0.86 2 ? 0.9 0.0 1 6.9e+02 42 76 .. 53 84 .. 48 88 .. 0.76 3 ? 0.2 0.0 1.7 1.2e+03 34 76 .. 122 164 .. 104 168 .. 0.70 4 ? -0.9 0.0 3.6 2.4e+03 40 66 .. 170 197 .. 145 208 .. 0.68 5 ? 4.5 0.0 0.077 52 35 75 .. 207 243 .. 190 247 .. 0.73 6 ? 2.4 0.0 0.35 2.4e+02 37 76 .. 288 324 .. 261 327 .. 0.82 7 ? 1.7 0.0 0.58 3.9e+02 23 72 .. 308 360 .. 298 364 .. 0.71 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.051 Rapsyn_N 55 emGkykealefslaqlniaeeledP 79 G ++e+l+ +qlniae dP FUN_000345-T1 23 TPGNFREVLDKHENQLNIAEKAGDP 47 5699****************99888 PP == domain 2 score: 0.9 bits; conditional E-value: 1 Rapsyn_N 42 kfrllGylitahsemGkykealefslaqlniaeel 76 + lG +++hs++ k a+e ++ lnia+e FUN_000345-T1 53 AYFHLGNTYKSHSNFPK---AIECYKNSLNIAREA 84 55668999999998665...788888889999986 PP == domain 3 score: 0.2 bits; conditional E-value: 1.7 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 ++t dr l ah + a+e + lnia+e FUN_000345-T1 122 RETGDRATEGDAYFNLGIAHDSNRDFPKAIECYEKSLNIAREA 164 667766555555555667899999999999999999****996 PP == domain 4 score: -0.9 bits; conditional E-value: 3.6 Rapsyn_N 40 edkfrl.lGylitahsemGkykealefs 66 e+k + lG+ + +hs++ + e e s FUN_000345-T1 170 EGKANFnLGIAYDSHSDFPRATECYEKS 197 4443322899999999988877766654 PP == domain 5 score: 4.5 bits; conditional E-value: 0.077 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaee 75 + + +d + lG+ + +hs++ k a+e ++ lnia+e FUN_000345-T1 207 R-ATEGDAYFNLGIAYHSHSDFPK---AIECYKKSLNIARE 243 3.3457777889********9776...77778888999998 PP == domain 6 score: 2.4 bits; conditional E-value: 0.35 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeel 76 s ed + lG+ + +hs+ + +a+e + lnia+e FUN_000345-T1 288 STEEDVYFNLGIAYHSHSD---FPNAIECYGKSLNIAREA 324 567899999********99...678999888999999986 PP == domain 7 score: 1.7 bits; conditional E-value: 0.58 Rapsyn_N 23 ekalrvWrkvlkktsdredkf...rllGylitahsemGkykealefslaqlni 72 +a+ + k l + + +d+f r + yl+ +s +G + +a e+ + l i FUN_000345-T1 308 PNAIECYGKSLNIAREAGDRFgvsRAIHYLVICYSALGEFSQAAEYREEYLKI 360 56777777777666666666633367999***********9999988777665 PP >> TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 2.8 1.9e+03 55 71 .. 64 80 .. 57 93 .. 0.81 2 ? 1.3 0.0 0.65 4.4e+02 56 71 .. 105 120 .. 96 129 .. 0.84 3 ? 2.8 0.0 0.21 1.4e+02 55 71 .. 144 160 .. 121 166 .. 0.81 4 ? 2.9 0.0 0.2 1.4e+02 54 72 .. 223 241 .. 197 253 .. 0.84 5 ? -0.5 0.0 2.2 1.5e+03 55 68 .. 264 277 .. 259 284 .. 0.80 6 ? 7.0 0.0 0.011 7.1 54 104 .. 303 351 .. 296 359 .. 0.82 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 2.8 TPR_BSK1_C 55 akdfktaiecytqfida 71 + +f +aiecy + ++ FUN_000345-T1 64 HSNFPKAIECYKNSLNI 80 57899******987765 PP == domain 2 score: 1.3 bits; conditional E-value: 0.65 TPR_BSK1_C 56 kdfktaiecytqfida 71 df +aiecy ++++ FUN_000345-T1 105 SDFPKAIECYEKILSI 120 59********999865 PP == domain 3 score: 2.8 bits; conditional E-value: 0.21 TPR_BSK1_C 55 akdfktaiecytqfida 71 ++df +aiecy + ++ FUN_000345-T1 144 NRDFPKAIECYEKSLNI 160 79*********998765 PP == domain 4 score: 2.9 bits; conditional E-value: 0.2 TPR_BSK1_C 54 rakdfktaiecytqfidag 72 + df +aiecy + ++ FUN_000345-T1 223 SHSDFPKAIECYKKSLNIA 241 478*********9988765 PP == domain 5 score: -0.5 bits; conditional E-value: 2.2 TPR_BSK1_C 55 akdfktaiecytqf 68 + df +ai+cy FUN_000345-T1 264 HSDFPKAIKCYQMS 277 78*********765 PP == domain 6 score: 7.0 bits; conditional E-value: 0.011 TPR_BSK1_C 54 rakdfktaiecytqfidagtmvsptvyarrslsylmsdkpqeALkdamqaq 104 + df +aiecy + ++ + + + r++ yl+ +AL++ qa FUN_000345-T1 303 SHSDFPNAIECYGKSLNIAREAGDRFGVSRAIHYLVI--CYSALGEFSQAA 351 578*******************************994..456666666665 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.041 28 15 33 .. 65 83 .. 62 88 .. 0.87 2 ? 1.7 0.0 0.4 2.7e+02 17 31 .. 147 161 .. 143 165 .. 0.87 3 ? -0.9 0.0 2.5 1.7e+03 17 30 .. 187 200 .. 184 204 .. 0.83 4 ? 3.2 0.0 0.13 90 16 33 .. 226 243 .. 223 247 .. 0.84 5 ? -2.3 0.0 6.9 4.7e+03 17 30 .. 267 280 .. 264 283 .. 0.84 6 ? 1.1 0.0 0.61 4.1e+02 16 32 .. 306 322 .. 303 325 .. 0.86 7 ? 0.4 0.0 0.98 6.6e+02 3 15 .. 340 352 .. 340 352 .. 0.91 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.041 SHNi-TPR 15 enFeqAvkDlrkaLeLree 33 +nF+ A++ ++ +L++ +e FUN_000345-T1 65 SNFPKAIECYKNSLNIARE 83 8**************9766 PP == domain 2 score: 1.7 bits; conditional E-value: 0.4 SHNi-TPR 17 FeqAvkDlrkaLeLr 31 F+ A++ ++k+L++ FUN_000345-T1 147 FPKAIECYEKSLNIA 161 999**********95 PP == domain 3 score: -0.9 bits; conditional E-value: 2.5 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A + ++k+L++ FUN_000345-T1 187 FPRATECYEKSLNI 200 8889999******9 PP == domain 4 score: 3.2 bits; conditional E-value: 0.13 SHNi-TPR 16 nFeqAvkDlrkaLeLree 33 F+ A++ ++k+L++ +e FUN_000345-T1 226 DFPKAIECYKKSLNIARE 243 59************9766 PP == domain 5 score: -2.3 bits; conditional E-value: 6.9 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A+k ++ +L++ FUN_000345-T1 267 FPKAIKCYQMSLSI 280 99999999999998 PP == domain 6 score: 1.1 bits; conditional E-value: 0.61 SHNi-TPR 16 nFeqAvkDlrkaLeLre 32 F+ A++ + k+L++ + FUN_000345-T1 306 DFPNAIECYGKSLNIAR 322 59************955 PP == domain 7 score: 0.4 bits; conditional E-value: 0.98 SHNi-TPR 3 vydlLGEiSLEne 15 +y LGE S+ +e FUN_000345-T1 340 CYSALGEFSQAAE 352 9*******99887 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.0 0.00034 0.23 2 46 .. 413 457 .. 412 486 .. 0.83 2 ! 7.6 0.0 0.0054 3.6 45 83 .. 606 644 .. 583 649 .. 0.82 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00034 Ras 2 lvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgk 46 ++l+G++ GK+sl + +F+ + +sT+g+d + ++v + FUN_000345-T1 413 IMLIGQERSGKTSLKKSLQGLQFNPDEDSTVGIDVDPSYFKVTTE 457 689*******************************87766666544 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0054 Ras 45 gkevklqiwDTAGqerfralreayyrgaegillvydits 83 + ++ +wD AG + + +++++++ + llvyd+++ FUN_000345-T1 606 EDDIYSVLWDFAGESVYYETHQLFLTSRAIYLLVYDLSR 644 45666779****************************975 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.17 1.1e+02 3 30 .. 93 120 .. 92 128 .. 0.87 2 ? 3.6 0.0 0.31 2.1e+02 3 33 .. 133 163 .. 131 175 .. 0.81 3 ? 0.3 0.0 3.7 2.5e+03 3 29 .. 213 239 .. 211 253 .. 0.86 4 ? 4.3 0.0 0.19 1.2e+02 3 30 .. 333 360 .. 331 365 .. 0.88 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.17 TPR_14 3 awlalarallalGdpdeAlelleralal 30 a+ l+ a+ l d+ +A+e++e++l+ FUN_000345-T1 93 AYFNLGSAYKLLSDFPKAIECYEKILSI 120 678899******************9986 PP == domain 2 score: 3.6 bits; conditional E-value: 0.31 TPR_14 3 awlalarallalGdpdeAlelleralaldPd 33 a+ l+ a+ + d+ +A+e++e+ l + FUN_000345-T1 133 AYFNLGIAHDSNRDFPKAIECYEKSLNIARE 163 7888999****************99876655 PP == domain 3 score: 0.3 bits; conditional E-value: 3.7 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+ l+ a+ d+ +A+e++++ l FUN_000345-T1 213 AYFNLGIAYHSHSDFPKAIECYKKSLN 239 78889999999***********99775 PP == domain 4 score: 4.3 bits; conditional E-value: 0.19 TPR_14 3 awlalarallalGdpdeAlelleralal 30 a ++l+ + alG++++A+e+ e++l+ FUN_000345-T1 333 AIHYLVICYSALGEFSQAAEYREEYLKI 360 67889999*************9999985 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.059 39 65 104 .. 63 102 .. 62 126 .. 0.92 2 ? 2.9 0.0 0.22 1.5e+02 64 105 .. 142 183 .. 141 191 .. 0.89 3 ? 3.4 0.0 0.15 1e+02 64 103 .. 182 221 .. 178 232 .. 0.86 4 ? -0.1 0.0 1.8 1.2e+03 65 104 .. 223 262 .. 219 279 .. 0.83 5 ? -1.0 0.0 3.6 2.4e+03 65 98 .. 263 296 .. 262 307 .. 0.80 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.059 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqayd 104 sh ++ + e y+ ln+a+ g ++ e+ka +L +ay+ FUN_000345-T1 63 SHSNFPKAIECYKNSLNIAREAGDQTTEQKAYFNLGSAYK 102 789999999**********************999998885 PP == domain 2 score: 2.9 bits; conditional E-value: 0.22 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqayda 105 Ds+r++ + e ye ln+a+ g + e ka+ +L ayd+ FUN_000345-T1 142 DSNRDFPKAIECYEKSLNIAREAGDWAREGKANFNLGIAYDS 183 9***********************999999999998888865 PP == domain 3 score: 3.4 bits; conditional E-value: 0.15 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqay 103 Dsh ++ e ye ln+a++ g ++ e +a +L ay FUN_000345-T1 182 DSHSDFPRATECYEKSLNIARKAGDRATEGDAYFNLGIAY 221 9***********************9999888877776665 PP == domain 4 score: -0.1 bits; conditional E-value: 1.8 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaealLkqayd 104 sh ++ + e y+ ln+a+ g++ e ka +L ay+ FUN_000345-T1 223 SHSDFPKAIECYKKSLNIAREAGNRVREGKAYFNLWIAYH 262 7889999999**************9999998887776665 PP == domain 5 score: -1.0 bits; conditional E-value: 3.6 Ulvan_lyase_2nd 65 shrkndeteelyelalnlakrkgyteleekaeal 98 sh ++ + + y++ l++a+ g + ee++ + FUN_000345-T1 263 SHSDFPKAIKCYQMSLSIAREAGDWSTEEDVYFN 296 788899999***********99987777766555 PP >> ssDBP Phage single-stranded DNA-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.1 0.86 5.8e+02 18 49 .. 50 80 .. 42 114 .. 0.79 2 ! 7.6 0.0 0.0075 5 17 57 .. 129 168 .. 116 179 .. 0.84 3 ? -0.5 0.0 2.5 1.7e+03 25 55 .. 176 206 .. 169 209 .. 0.80 4 ? 3.0 0.1 0.21 1.4e+02 17 46 .. 209 237 .. 197 248 .. 0.83 5 ? 2.5 0.0 0.3 2e+02 19 57 .. 251 288 .. 242 296 .. 0.83 6 ? 0.5 0.0 1.2 8.3e+02 26 47 .. 297 318 .. 290 328 .. 0.81 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.86 ssDBP 18 kGnpYtmaeafahledapfPqkisyyveskde 49 +G++Y + + +++ +fP+ i+ y +s + FUN_000345-T1 50 EGKAY-FHLGNTYKSHSNFPKAIECYKNSLNI 80 57777.455667788889*****999998654 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0075 ssDBP 17 akGnpYtmaeafahledapfPqkisyyveskdevlpaGeye 57 ++G++Y ++ + ah ++ +fP+ i+ y +s + +aG+++ FUN_000345-T1 129 TEGDAY-FNLGIAHDSNRDFPKAIECYEKSLNIAREAGDWA 168 568888.68899******************99899999997 PP == domain 3 score: -0.5 bits; conditional E-value: 2.5 ssDBP 25 aeafahledapfPqkisyyveskdevlpaGe 55 + + a+ + +fP+ + y +s + +aG+ FUN_000345-T1 176 NLGIAYDSHSDFPRATECYEKSLNIARKAGD 206 5578999**********99999766666665 PP == domain 4 score: 3.0 bits; conditional E-value: 0.21 ssDBP 17 akGnpYtmaeafahledapfPqkisyyves 46 ++G++Y ++ + a+ + +fP+ i+ y +s FUN_000345-T1 209 TEGDAY-FNLGIAYHSHSDFPKAIECYKKS 237 467787.678999**************998 PP == domain 5 score: 2.5 bits; conditional E-value: 0.3 ssDBP 19 GnpYtmaeafahledapfPqkisyyveskdevlpaGeye 57 G++Y ++ a+ + +fP+ i+ y s +aG++ FUN_000345-T1 251 GKAY-FNLWIAYHSHSDFPKAIKCYQMSLSIAREAGDWS 288 6666.455679999***********99988888899986 PP == domain 6 score: 0.5 bits; conditional E-value: 1.2 ssDBP 26 eafahledapfPqkisyyvesk 47 + a+ + +fP i+ y +s FUN_000345-T1 297 LGIAYHSHSDFPNAIECYGKSL 318 577999************9995 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.15 1e+02 125 174 .. 37 84 .. 27 89 .. 0.85 2 ? 2.8 0.0 0.13 90 101 215 .. 93 203 .. 84 217 .. 0.77 3 ? -1.6 0.0 3 2e+03 136 172 .. 206 242 .. 171 247 .. 0.61 4 ? 5.8 0.0 0.016 11 100 174 .. 292 364 .. 268 372 .. 0.82 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.15 TPR_NPHP3 125 aLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 L+i e a dP + ++++ +L + y +f +a + yk++l+i ++a FUN_000345-T1 37 QLNIAEKAGDPAEE--GKAYFHLGNTYKSHSNFPKAIECYKNSLNIAREA 84 57777888777664..78999************************98765 PP == domain 2 score: 2.8 bits; conditional E-value: 0.13 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLei.RetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqk 195 y lG k l+ +a++ ++ L i Ret D + ++ +L ++ + f +a + y+++l+i ++a d k l + y FUN_000345-T1 93 AYFNLGSAYKLLSDFPKAIECYEKILSIaRETG---DRATEGDAYFNLGIAHDSNRDFPKAIECYEKSLNIAREAG--DWAREGKANFNLGIAYDS 183 58889999999999999********99967776...999999****************************998763..333333333445666666 PP TPR_NPHP3 196 qdkhdlaeplkkravairkk 215 + + a + +++++i +k FUN_000345-T1 184 HSDFPRATECYEKSLNIARK 203 66666666666666666655 PP == domain 3 score: -1.6 bits; conditional E-value: 3 TPR_NPHP3 136 DhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 D + ++ +L y f +a + yk++l+i + FUN_000345-T1 206 DRATEGDAYFNLGIAYHSHSDFPKAIECYKKSLNIAR 242 4445555666666677777777777777777777765 PP == domain 4 score: 5.8 bits; conditional E-value: 0.016 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 d+y lG + + a++ ++L+i a D v+r+ h+L y+ g+fs+a ++ ++ l+i++ FUN_000345-T1 292 DVYFNLGIAYHSHSDFPNAIECYGKSLNIAREA--GDRFGVSRAIHYLVICYSALGEFSQAAEYREEYLKIVNGV 364 677777777777888888899999999985555..59999**********************9999999998765 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.33 2.2e+02 136 176 .. 53 92 .. 51 93 .. 0.90 2 ? 1.5 0.1 0.49 3.3e+02 133 175 .. 70 131 .. 68 133 .. 0.76 3 ? 5.5 0.2 0.028 19 133 172 .. 150 208 .. 109 213 .. 0.58 4 ? 1.3 0.0 0.57 3.8e+02 135 174 .. 212 250 .. 211 253 .. 0.85 5 ? 2.2 0.1 0.3 2e+02 133 173 .. 230 289 .. 228 293 .. 0.67 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.33 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkeepe 176 aY + ++ ++ +a+++++ +l +a+++g++ +e++ FUN_000345-T1 53 AYFHLGNTYKSH-SNFPKAIECYKNSLNIAREAGDQTTEQK 92 899999999998.999*******************999876 PP == domain 2 score: 1.5 bits; conditional E-value: 0.49 DUF7380 133 AidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrkeep 175 Ai++Y +s + +++ + +a++++e+ l++a++ g+r++e FUN_000345-T1 70 AIECYKNSLNIAREAgdqtteqkayfnlgsayklLSDFPKAIECYEKILSIARETGDRATEG 131 77777766666665566677777777777777776889999999999999999999998875 PP == domain 3 score: 5.5 bits; conditional E-value: 0.028 DUF7380 133 AidaY...lesaeeledg................seewvdalkrleRAlqlaaqlgkrk 172 Ai++Y l++a+e+ d+ + +a +++e++l +a+++g+r+ FUN_000345-T1 150 AIECYeksLNIAREAGDWaregkanfnlgiaydsHSDFPRATECYEKSLNIARKAGDRA 208 44444222222333333355555555555554444455556666666666666666655 PP == domain 4 score: 1.3 bits; conditional E-value: 0.57 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daY + + + +a+++++++l +a+++g r +e FUN_000345-T1 212 DAYFNLGIAYHSH-SDFPKAIECYKKSLNIAREAGNRVRE 250 6888888888887.8899***************9998765 PP == domain 5 score: 2.2 bits; conditional E-value: 0.3 DUF7380 133 AidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrke 173 Ai++Y +s + +++ + +a+k+++++l++a+++g+ ++ FUN_000345-T1 230 AIECYKKSLNIAREAgnrvregkayfnlwiayhsHSDFPKAIKCYQMSLSIAREAGDWST 289 5566655555444444556666666666666555588999************99987665 PP >> Clathrin Region in Clathrin and VPS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.14 95 62 116 .. 28 84 .. 22 102 .. 0.70 2 ? 2.3 0.0 0.26 1.8e+02 75 120 .. 123 169 .. 120 174 .. 0.83 3 ? 3.0 0.0 0.16 1.1e+02 77 114 .. 205 242 .. 179 252 .. 0.81 4 ? -0.5 0.0 1.9 1.3e+03 81 111 .. 249 279 .. 241 290 .. 0.77 5 ? -0.2 0.0 1.6 1e+03 82 109 .. 290 317 .. 279 329 .. 0.65 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.14 Clathrin 62 eeflkefnn.yd.aekvaklcekaklyeealilYkknedwdeaisvlkknklykrai 116 +e+l++++n + aek ++ +e+ k y + Yk ++++ +ai+++k+ ++ r++ FUN_000345-T1 28 REVLDKHENqLNiAEKAGDPAEEGKAYFHLGNTYKSHSNFPKAIECYKNSLNIAREA 84 5666655555441356667777777776666699***********999977776666 PP == domain 2 score: 2.3 bits; conditional E-value: 0.26 Clathrin 75 kvaklcekaklyeealilYkknedwdeaisvlkknklykrai.eyav 120 + ++++ + + y + i+++ n d+ +ai++++k ++ r++ ++a+ FUN_000345-T1 123 ETGDRATEGDAYFNLGIAHDSNRDFPKAIECYEKSLNIAREAgDWAR 169 56888889999999999**************8887777777667665 PP == domain 3 score: 3.0 bits; conditional E-value: 0.16 Clathrin 77 aklcekaklyeealilYkknedwdeaisvlkknklykr 114 ++++ + + y + i+Y ++d+ +ai+++kk ++ r FUN_000345-T1 205 GDRATEGDAYFNLGIAYHSHSDFPKAIECYKKSLNIAR 242 67777778888888899999999999999988666655 PP == domain 4 score: -0.5 bits; conditional E-value: 1.9 Clathrin 81 ekaklyeealilYkknedwdeaisvlkknkl 111 + k y + i+Y ++d+ +ai++++ + FUN_000345-T1 249 REGKAYFNLWIAYHSHSDFPKAIKCYQMSLS 279 566677778899999********99876555 PP == domain 5 score: -0.2 bits; conditional E-value: 1.6 Clathrin 82 kaklyeealilYkknedwdeaisvlkkn 109 + + y + i+Y ++d+ +ai+++ k FUN_000345-T1 290 EEDVYFNLGIAYHSHSDFPNAIECYGKS 317 5556666666666677777776665443 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.64 4.3e+02 3 30 .. 93 116 .. 91 117 .. 0.68 2 ? 5.9 0.0 0.044 30 2 31 .. 132 157 .. 131 159 .. 0.82 3 ? 2.8 0.1 0.41 2.8e+02 2 31 .. 212 237 .. 211 239 .. 0.72 4 ? -0.4 0.0 4.5 3e+03 20 31 .. 266 277 .. 264 279 .. 0.87 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.64 Sel1 3 AqyrLGylylyGlg.vpkDpekAlewyek 30 A+++LG + + + D kA+e+yek FUN_000345-T1 93 AYFNLGSA-----YkLLSDFPKAIECYEK 116 55555532.....22456999******98 PP == domain 2 score: 5.9 bits; conditional E-value: 0.044 Sel1 2 eAqyrLGylylyGlgvpkDpekAlewyekA 31 +A+++LG + + +D kA+e+yek+ FUN_000345-T1 132 DAYFNLGI--AHDS--NRDFPKAIECYEKS 157 68888886..6665..9***********96 PP == domain 3 score: 2.8 bits; conditional E-value: 0.41 Sel1 2 eAqyrLG.ylylyGlgvpkDpekAlewyekA 31 +A+++LG ++ + D kA+e+y+k+ FUN_000345-T1 212 DAYFNLGiAYHSHS-----DFPKAIECYKKS 237 57888886534444.....899999999996 PP == domain 4 score: -0.4 bits; conditional E-value: 4.5 Sel1 20 DpekAlewyekA 31 D kA+++y+++ FUN_000345-T1 266 DFPKAIKCYQMS 277 889******985 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 2.1 1.4e+03 70 93 .. 65 88 .. 58 103 .. 0.82 2 ? -1.3 0.0 5.2 3.5e+03 70 90 .. 105 125 .. 100 132 .. 0.83 3 ? 3.3 0.0 0.19 1.3e+02 67 90 .. 142 165 .. 140 216 .. 0.66 4 ? 2.7 0.0 0.3 2e+02 70 92 .. 225 247 .. 220 267 .. 0.85 5 ? -1.2 0.0 4.8 3.3e+03 70 91 .. 265 286 .. 260 294 .. 0.82 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 2.1 DUF7018 70 kllekaidhyekslklieeavekk 93 ++ kai+ y++sl++++ea +++ FUN_000345-T1 65 SNFPKAIECYKNSLNIAREAGDQT 88 5799************99997764 PP == domain 2 score: -1.3 bits; conditional E-value: 5.2 DUF7018 70 kllekaidhyekslklieeav 90 ++ kai+ yek l++++e+ FUN_000345-T1 105 SDFPKAIECYEKILSIARETG 125 5899***********998875 PP == domain 3 score: 3.3 bits; conditional E-value: 0.19 DUF7018 67 dvqkllekaidhyekslklieeav 90 d +++ kai+ yeksl++++ea FUN_000345-T1 142 DSNRDFPKAIECYEKSLNIAREAG 165 567788888999999888888874 PP == domain 4 score: 2.7 bits; conditional E-value: 0.3 DUF7018 70 kllekaidhyekslklieeavek 92 ++ kai+ y+ksl++++ea ++ FUN_000345-T1 225 SDFPKAIECYKKSLNIAREAGNR 247 7999*************999776 PP == domain 5 score: -1.2 bits; conditional E-value: 4.8 DUF7018 70 kllekaidhyekslklieeave 91 ++ kai+ y+ sl++++ea + FUN_000345-T1 265 SDFPKAIKCYQMSLSIAREAGD 286 6899************999855 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.24 1.6e+02 130 153 .] 55 78 .. 50 78 .. 0.90 2 ? -1.1 0.0 4.2 2.8e+03 5 28 .. 97 120 .. 94 128 .. 0.79 3 ? -0.7 0.0 3.3 2.2e+03 132 153 .] 137 158 .. 127 158 .. 0.82 4 ? 1.8 0.0 0.53 3.5e+02 132 153 .] 217 238 .. 209 242 .. 0.83 5 ? 1.2 0.0 0.83 5.5e+02 91 140 .. 1193 1242 .. 1185 1250 .. 0.86 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.24 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 ++l++++ s++++ kai++Yk++L FUN_000345-T1 55 FHLGNTYKSHSNFPKAIECYKNSL 78 578999***************987 PP == domain 2 score: -1.1 bits; conditional E-value: 4.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G a+ ++ kAi+ Ye++l++ FUN_000345-T1 97 LGSAYKLLSDFPKAIECYEKILSI 120 577777778899999999998876 PP == domain 3 score: -0.7 bits; conditional E-value: 3.3 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s+rd+ kai++Y +L FUN_000345-T1 137 LGIAHDSNRDFPKAIECYEKSL 158 556677899999***9998876 PP == domain 4 score: 1.8 bits; conditional E-value: 0.53 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ ++s++d+ kai++Yk +L FUN_000345-T1 217 LGIAYHSHSDFPKAIECYKKSL 238 6667888999999999999876 PP == domain 5 score: 1.2 bits; conditional E-value: 0.83 ARM_TT21_4th 91 ealetLkkakelqarvlkrvsveqpdaveeqkklaakiclqlAehaaser 140 + ++ L +ake+ ++ +++++eq+d + ++++ i + +A+ s+r FUN_000345-T1 1193 SLVSPLCDAKEIVLQLKENLHLEQTDLEKPTPETMKMIRCLVAKAKYSNR 1242 56788999*********************************999766554 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.00018 0.12 4 26 .. 413 435 .. 409 448 .. 0.89 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00018 PduV-EutP 4 illiGkvgsGKttLtqalkgeel 26 i+liG+ sGKt+L+++l+g+++ FUN_000345-T1 413 IMLIGQERSGKTSLKKSLQGLQF 435 9******************9886 PP >> Cerato-platanin Cerato-platanin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.12 78 65 100 .. 59 94 .. 39 102 .. 0.86 2 ? 0.9 0.0 1 6.7e+02 64 99 .. 178 213 .. 164 218 .. 0.87 3 ? 0.6 0.0 1.3 8.6e+02 64 99 .. 218 253 .. 215 257 .. 0.91 4 ? 0.2 0.0 1.7 1.1e+03 64 99 .. 298 333 .. 283 339 .. 0.86 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.12 Cerato-platanin 65 ityngktiyvlaidaagaGfniakkamdeltngqaa 100 ty++++ + ai+ + +nia++a d+ t+++a FUN_000345-T1 59 NTYKSHSNFPKAIECYKNSLNIAREAGDQTTEQKAY 94 4899999999*********************99884 PP == domain 2 score: 0.9 bits; conditional E-value: 1 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqa 99 +i y++++ + a + + +nia+ka d+ t+g a FUN_000345-T1 178 GIAYDSHSDFPRATECYEKSLNIARKAGDRATEGDA 213 688999999999999999**************9988 PP == domain 3 score: 0.6 bits; conditional E-value: 1.3 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqa 99 +i y++++ + ai+ + +nia++a +++ +g+a FUN_000345-T1 218 GIAYHSHSDFPKAIECYKKSLNIAREAGNRVREGKA 253 588999999999******************999987 PP == domain 4 score: 0.2 bits; conditional E-value: 1.7 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqa 99 +i y++++ + ai+ g+ +nia++a d++ ++a FUN_000345-T1 298 GIAYHSHSDFPNAIECYGKSLNIAREAGDRFGVSRA 333 68999999999****************998876666 PP >> Glyco_tran_10_N Fucosyltransferase, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 4.3 2.9e+03 85 104 .. 88 107 .. 75 110 .. 0.82 2 ? 1.2 0.0 1 6.9e+02 86 104 .. 209 227 .. 196 230 .. 0.84 3 ? 3.3 0.0 0.23 1.5e+02 85 104 .. 248 267 .. 239 271 .. 0.83 4 ? 0.5 0.0 1.7 1.1e+03 88 105 .. 291 308 .. 279 311 .. 0.83 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 4.3 Glyco_tran_10_N 85 leelenlfNltmtYrrdsdi 104 ++e + +fNl Y++ sd+ FUN_000345-T1 88 TTEQKAYFNLGSAYKLLSDF 107 556789***********997 PP == domain 2 score: 1.2 bits; conditional E-value: 1 Glyco_tran_10_N 86 eelenlfNltmtYrrdsdi 104 +e + +fNl + Y++ sd+ FUN_000345-T1 209 TEGDAYFNLGIAYHSHSDF 227 55689*************7 PP == domain 3 score: 3.3 bits; conditional E-value: 0.23 Glyco_tran_10_N 85 leelenlfNltmtYrrdsdi 104 ++e + +fNl++ Y++ sd+ FUN_000345-T1 248 VREGKAYFNLWIAYHSHSDF 267 566778*************7 PP == domain 4 score: 0.5 bits; conditional E-value: 1.7 Glyco_tran_10_N 88 lenlfNltmtYrrdsdif 105 + +fNl + Y++ sd+ FUN_000345-T1 291 EDVYFNLGIAYHSHSDFP 308 5679************75 PP >> Foie-gras_1 Foie gras liver health family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.035 23 146 221 .. 47 122 .. 13 126 .. 0.86 2 ? 2.9 0.0 0.15 1e+02 168 252 .. 229 313 .. 190 319 .. 0.82 3 ? -1.2 0.0 2.8 1.9e+03 193 216 .. 814 837 .. 794 842 .. 0.84 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.035 Foie-gras_1 146 apepheetelegseekgvdhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplalsyr 221 e+ +++ g+++k+ + +i+++k++l +++ + + ++++ ++++ +y l d+ ka+e ++ + ++ r FUN_000345-T1 47 PAEEGKAYFHLGNTYKSHSNFPKAIECYKNSLNIAREAGDQTTEQKAYFNLGSAYKLLSDFPKAIECYEKILSIAR 122 556667777777777777777889*******************************************998866655 PP == domain 2 score: 2.9 bits; conditional E-value: 0.15 Foie-gras_1 168 liidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplalsyrqegWwsLleevlwalrecalkvgdvkdvlrv 252 +i+++k++l +++ + + + + +++ +y d+ ka++ +++ ++ r++g ws e+v l ++ +d+ +++++ FUN_000345-T1 229 KAIECYKKSLNIAREAGNRVREGKAYFNLWIAYHSHSDFPKAIKCYQMSLSIAREAGDWSTEEDVYFNLGIAYHSHSDFPNAIEC 313 5788999998888755554445556669999999***************999999999999999999999999998888888877 PP == domain 3 score: -1.2 bits; conditional E-value: 2.8 Foie-gras_1 193 sleiAeEylrlgdwakalellrpl 216 + +iA E ++gd+++ +++++ l FUN_000345-T1 814 AEQIASEICQIGDHQEFVTMIDFL 837 559**************9999876 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.3 0.06 40 129 166 .. 51 88 .. 46 125 .. 0.65 2 ? 2.9 0.1 0.18 1.2e+02 130 160 .. 132 162 .. 91 166 .. 0.75 3 ? 0.7 0.0 0.82 5.5e+02 130 160 .. 172 202 .. 169 209 .. 0.86 4 ? -0.2 0.0 1.6 1.1e+03 131 163 .. 213 245 .. 209 257 .. 0.86 5 ? -1.8 0.0 5 3.4e+03 135 174 .. 297 336 .. 292 341 .. 0.83 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.06 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskesspav 166 +kAy lG + +++++ +A+e+Y+++ +++ e+ + FUN_000345-T1 51 GKAYFHLGNTYKSHSNFPKAIECYKNSLNIAREAGDQT 88 69999999999999999999999999998866544333 PP == domain 2 score: 2.9 bits; conditional E-value: 0.18 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklsk 160 Ay lG+ ++++ + +A+e+Yek+ +++ FUN_000345-T1 132 DAYFNLGIAHDSNRDFPKAIECYEKSLNIAR 162 4777899999999**********99877765 PP == domain 3 score: 0.7 bits; conditional E-value: 0.82 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklsk 160 kA lG+ +++++ + A e+Yek+ +++ FUN_000345-T1 172 KANFNLGIAYDSHSDFPRATECYEKSLNIAR 202 677789*******************988765 PP == domain 4 score: -0.2 bits; conditional E-value: 1.6 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklskess 163 Ay lG+ + +++ + +A+e+Y+k+ +++ e+ FUN_000345-T1 213 AYFNLGIAYHSHSDFPKAIECYKKSLNIAREAG 245 788899******************999887765 PP == domain 5 score: -1.8 bits; conditional E-value: 5 ARM_TT21_C 135 lGliaekeqsykdAaenYekAWklskesspavGykLAfny 174 lG+ + +++ + +A+e+Y k+ +++ e+ + G A +y FUN_000345-T1 297 LGIAYHSHSDFPNAIECYGKSLNIAREAGDRFGVSRAIHY 336 789999999***********99999888777776666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1325 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1035 (0.0405167); expected 510.9 (0.02) Passed bias filter: 826 (0.0323351); expected 510.9 (0.02) Passed Vit filter: 86 (0.00336661); expected 25.5 (0.001) Passed Fwd filter: 38 (0.00148757); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 38 [number of targets reported over threshold] # CPU time: 0.61u 0.37s 00:00:00.98 Elapsed: 00:00:00.45 # Mc/sec: 11926.76 // Query: FUN_000346-T1 [L=75] Description: FUN_000346 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (75 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 283 (0.0110785); expected 510.9 (0.02) Passed bias filter: 271 (0.0106087); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.39s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 758.20 // Query: FUN_000347-T1 [L=344] Description: FUN_000347 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-25 88.5 0.1 9.9e-25 87.6 0.1 1.4 1 Ephrin Ephrin ------ inclusion threshold ------ 0.055 13.8 10.6 0.47 10.8 10.6 2.1 1 TMEM154 TMEM154 protein family 0.075 13.7 0.8 0.15 12.8 0.8 1.5 1 DUF2905 Protein of unknown function (DUF2905) 1.5 8.2 10.7 2.7 7.3 10.7 1.3 1 US29 Cytomegalovirus US29 protein Domain annotation for each model (and alignments): >> Ephrin Ephrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.6 0.1 1.5e-28 9.9e-25 7 140 .] 26 163 .. 21 163 .. 0.88 Alignments for each domain: == domain 1 score: 87.6 bits; conditional E-value: 1.5e-28 Ephrin 7 avyWnssnpkfrkedyvlevkigdyldiiCPkyeesev....eeeeaeyy.klYlVekeeyeeCelekkkellleCdkpeaeekftekfqefspfp 97 +++W np f+++d+ ++v +l i+CP+ ++ + + ++ e y + + V++e ye+C++++ ++ ll+C++p + ++ft fqe+s++ FUN_000347-T1 26 TIHWAPDNPLFERNDSLIYVFPSSKLSIVCPNPSTVLKtardSISKNELYqNFWIVSRESYERCDTSQGSRRLLKCNEPLRLKYFTLVFQEYSAVN 121 89*****************************9876544322223334555156789*************************************987 PP Ephrin 98 lGleFqegeeYYyistssgklegleekkggvCekknlklkvkv 140 + +geeYY+i+ts+g+++ + ++gg+C++ n++lk++v FUN_000347-T1 122 HP-VYIPGEEYYFIATSDGTHRSVGWRSGGNCKRANMRLKIHV 163 76.59***********************************987 PP >> TMEM154 TMEM154 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 10.6 7.3e-05 0.47 14 102 .. 209 308 .. 168 320 .. 0.61 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 7.3e-05 TMEM154 14 dtaletetleeetataslaavteteslk...........qeeakanlsstdldneedqlefil....mviiPlvlliilllvvvilitkykrkRaK 94 +t+ ++ t++++t a++ a+t + sl ++ + +s d + +++ +e + mv+iPl++ ++l+l + i+ ++r +++ FUN_000347-T1 209 STTASSVTPQKTT--ATTHASTFSTSLLrssvvarttkqDTQGPVARASSDDQHQKNLIEAVTglnwMVVIPLMACLLLSLLGNIIL--ICRLKIR 300 4444444444333..3334444444443344443321111222333444444555555555524455************99997776..5777777 PP TMEM154 95 ddekseae 102 d ++ + FUN_000347-T1 301 DHGYQLPH 308 77665544 PP >> DUF2905 Protein of unknown function (DUF2905) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.8 2.3e-05 0.15 38 61 .. 270 293 .. 267 295 .. 0.88 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2.3e-05 DUF2905 38 rgnftfyfPlttsillSlvlslll 61 + n+ +++Pl+ ++llSl+ ++l FUN_000347-T1 270 GLNWMVVIPLMACLLLSLLGNIIL 293 568899**************9997 PP >> US29 Cytomegalovirus US29 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 10.7 0.00042 2.7 29 123 .. 177 282 .. 164 286 .. 0.51 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.00042 US29 29 tstvraqstvvkeesspvsttssavnvtatsnvstvvtrpaeststteelntasptrqvrkdevdarrrqrlr............kpnysaCvtet 112 t+t++ +t + +++ ++ +++++ t++s +st+ +++ +t ++ ++ t+ +r++ v + +q+++ + n+ + vt+ FUN_000347-T1 177 TATTGKRTTKTIPTTKAST-ETRSTRKTSQSIISTTASSVTPQKTTATTHASTFSTSLLRSSVVARTTKQDTQgpvarassddqhQKNLIEAVTGL 271 4444444444443333333.2333344444444444444433333333332222333334444444444444444444444444477889999999 PP US29 113 tWltnlafskC 123 +W++ +++ C FUN_000347-T1 272 NWMVVIPLMAC 282 99999999888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (344 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1191 (0.0466236); expected 510.9 (0.02) Passed bias filter: 580 (0.022705); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 3436.97 // Query: FUN_000348-T1 [L=333] Description: FUN_000348 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-23 83.3 0.3 3.5e-23 82.6 0.3 1.3 1 Ephrin Ephrin ------ inclusion threshold ------ 0.038 14.0 0.0 0.066 13.2 0.0 1.4 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.069 11.6 3.8 0.085 11.3 3.8 1.1 1 Dicty_REP Dictyostelium (Slime Mold) REP protein 0.077 14.4 0.0 0.21 13.1 0.0 1.7 1 CS CS domain 0.11 11.9 1.0 0.15 11.5 1.0 1.1 1 Otopetrin Otopetrin 0.5 10.1 2.9 0.17 11.6 0.5 1.5 2 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 1.6 7.3 6.6 2 6.9 6.6 1.2 1 Sporozoite_P67 Sporozoite P67 surface antigen Domain annotation for each model (and alignments): >> Ephrin Ephrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.6 0.3 9.7e-27 3.5e-23 7 140 .] 28 164 .. 24 164 .. 0.90 Alignments for each domain: == domain 1 score: 82.6 bits; conditional E-value: 9.7e-27 Ephrin 7 avyWnssnpkfr.kedyvlevkigdyldiiCPkyeeseveeeea....eyyklYlVekeeyeeCelekkk.ellleCdkpeaeekftekfqefspf 96 +++W s+np f+ ++++ ++++ l ++CP++ + ++++ ey +l+lV +e ye+C++++ ++l C+kp + +++ f+e+ + FUN_000348-T1 28 SIHWTSTNPLFKrNRTQCVYPE--SILYFLCPNTVTVVAKTQDSflspEYENLWLVGEESYERCNVTQGVdRKLQVCNKPFELKSYRVIFREYGAG 121 79*********97777777775..79*******9987765555456669****************999877***********************99 PP Ephrin 97 plGleFqegeeYYyistssgklegleekkggvCekknlklkvkv 140 l + Fq+ge+YY+i+ts+g++ +++++gg+C+++n+klk+++ FUN_000348-T1 122 NLPV-FQPGEDYYFIATSDGTAPSVDQTSGGHCKTHNMKLKFHI 164 9976.***********************************9875 PP >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 1.8e-05 0.066 150 193 .. 263 306 .. 233 330 .. 0.79 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1.8e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 150 evsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkkk 193 e t++ +v+gfl+p++++l c + il k+ +k ++kk+ FUN_000348-T1 263 ETNETVYHTVIGFLVPFCFLLSCVCVILLYKLKHTQKTARKKTI 306 55568999*******************98777777776664443 PP >> Dicty_REP Dictyostelium (Slime Mold) REP protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 3.8 2.3e-05 0.085 250 324 .. 188 266 .. 167 300 .. 0.59 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.3e-05 Dicty_REP 250 skeknkttttt..tttttttsqart.rkrkaidddklsenqakekkknskksdddp.qsdfskkssrksgslkdvrvdn 324 s+++++ttttt ttttttt++++ +k k+ + + +++a + ++ s+ ++ + + ++ +++g+ ++ + ++ FUN_000348-T1 188 SSTTAATTTTTatTTTTTTTPTPTSpTKAKTAEVNAQRRKPATSHLLETASSTISTiYTTPTTIMPDDNGNERNLETNE 266 3333333333300333333333322133333333333344444444445555444422333445567777777776665 PP >> CS CS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 5.6e-05 0.21 29 68 .. 152 192 .. 142 198 .. 0.86 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.6e-05 CS 29 kveikkrslkvki.kgknekliiegeLfkeIdpeesswtie 68 +++ +++lk++i +++++++++++L++ I p+++s t FUN_000348-T1 152 HCKTHNMKLKFHIcVNSTDPVCLNEDLCNGIVPSQASSTTA 192 56777888***************************999876 PP >> Otopetrin Otopetrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 1.0 4e-05 0.15 129 217 .. 207 317 .. 152 331 .. 0.56 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 4e-05 Otopetrin 129 e......skeessevskakekeskssieestt.......................lkeCertnilgslvqdaspfLypfiveYSliaaavlyvmWk 195 + +k++++ev+ +++k ++s + + ++ ++ +++++++ fL pf S++++ ly + k FUN_000348-T1 207 TptptspTKAKTAEVNAQRRKPATS------HlletasstistiyttpttimpddNGNERNLETNETVYHTVIGFLVPFCFLLSCVCVILLYKL-K 295 1112222222222222222222222......1222333455555556666666554444666777888************************99.5 PP Otopetrin 196 nigkkkkeeksvakseekeeas 217 +++k+ +++++ ++++e+++++ FUN_000348-T1 296 HTQKTARKKTILKQHAERNSSD 317 5555555555544444444444 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.1 2.2 8.2e+03 62 84 .. 41 63 .. 29 66 .. 0.73 2 ? 11.6 0.5 4.6e-05 0.17 175 237 .. 252 315 .. 185 321 .. 0.69 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 2.2 7TM_GPCR_Srw 62 eeseClppdsylkvlldlilesl 84 ++++C+ p+s+l +l+ ++++++ FUN_000348-T1 41 NRTQCVYPESILYFLCPNTVTVV 63 47889999998888888877776 PP == domain 2 score: 11.6 bits; conditional E-value: 4.6e-05 7TM_GPCR_Srw 175 lvvselftandglllkifllidgilskiipsillpiltilLiieLrkakksrkkls...kskknek 237 + ++ ++n + ++++ ++ g+l + ++ll + ++L+++L+ ++k+++k + +++++++ FUN_000348-T1 252 MPDDNGNERNLETNETVYHTVIGFL--VPFCFLLSCVCVILLYKLKHTQKTARKKTilkQHAERNS 315 4444444444445555566655555..566*******************99888876533333334 PP >> Sporozoite_P67 Sporozoite P67 surface antigen # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 6.6 0.00055 2 269 312 .. 186 226 .. 152 260 .. 0.72 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.00055 Sporozoite_P67 269 rvgdatssssttspssstttttpassgpsaqgspgsssrnavtr 312 + ++t++++tt+++++tttttp+ ++ + ++ na r FUN_000348-T1 186 QASSTTAATTTTTATTTTTTTTPTPTS---PTKAKTAEVNAQRR 226 334455555555555555555555555...55555555555444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (333 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1834 (0.0717949); expected 510.9 (0.02) Passed bias filter: 1015 (0.0397338); expected 510.9 (0.02) Passed Vit filter: 106 (0.00414954); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.36u 0.40s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 3244.48 // Query: FUN_000349-T1 [L=128] Description: FUN_000349 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 11.9 0.2 0.27 10.7 0.0 1.6 2 DUF2434 Protein of unknown function (DUF2434) Domain annotation for each model (and alignments): >> DUF2434 Protein of unknown function (DUF2434) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 1.1e-05 0.27 140 180 .. 16 56 .. 12 78 .. 0.92 2 ? -1.1 0.1 0.041 1.1e+03 76 96 .. 82 102 .. 65 110 .. 0.81 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 1.1e-05 DUF2434 140 eavrhwGswqerqlidpdpfalreddrrskvefllPlvfYl 180 +a hwGs q r+ + ++ + ++++r++ f +Pl + FUN_000349-T1 16 HAAEHWGSNQAREGLVENLCSSMNSSSRTNRFFQMPLAVFW 56 6789*********************************8764 PP == domain 2 score: -1.1 bits; conditional E-value: 0.041 DUF2434 76 peekrfepigrRwqwywlllv 96 +++ +++ +rR++++ +l+ FUN_000349-T1 82 KSKTKWYSSSRRARFIVILWQ 102 567789999999999988775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 643 (0.0251713); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1288.95 // Query: FUN_000350-T1 [L=218] Description: FUN_000350 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-64 216.9 0.1 1.8e-64 216.7 0.1 1.0 1 Ras Ras family 6.6e-36 123.6 0.1 9.6e-36 123.1 0.1 1.2 1 Roc Ras of Complex, Roc, domain of DAPkinase 5.5e-12 46.0 0.1 7e-12 45.6 0.1 1.2 1 Arf ADP-ribosylation factor family 1.6e-07 31.9 0.1 4.1e-07 30.6 0.0 1.7 2 MMR_HSR1 50S ribosome-binding GTPase 1.3e-05 25.3 0.1 6.6e-05 23.0 0.1 1.9 1 GTP_EFTU Elongation factor Tu GTP binding domain 1.9e-05 25.0 0.3 0.021 15.1 0.0 2.2 2 RsgA_GTPase RsgA GTPase 9.6e-05 23.2 0.0 0.00058 20.7 0.0 2.0 1 AAA_22 AAA domain ------ inclusion threshold ------ 0.012 15.9 0.0 0.023 15.0 0.0 1.6 1 PduV-EutP Ethanolamine utilisation - propanediol utilisat 0.019 16.0 0.1 0.028 15.5 0.1 1.6 1 ABC_tran ABC transporter 0.023 15.7 0.1 0.04 14.9 0.1 1.6 1 AAA_16 AAA ATPase domain 0.031 14.3 0.4 0.1 12.6 0.1 2.0 2 FeoB_N Ferrous iron transport protein B 0.047 14.0 0.1 0.084 13.2 0.1 1.5 1 NTPase_1 NTPase 0.049 13.5 0.0 0.067 13.1 0.0 1.3 1 Gtr1_RagA Gtr1/RagA G protein conserved region 0.05 13.6 0.0 0.26 11.2 0.0 2.0 2 TniB Bacterial TniB protein 0.061 13.8 0.1 0.24 11.9 0.1 2.0 2 AAA_14 AAA domain 0.14 12.1 0.0 0.16 11.9 0.0 1.2 1 DUF3289 Protein of unknown function (DUF3289) 0.16 12.2 0.0 0.33 11.1 0.0 1.5 1 AAA_24 AAA domain 0.18 11.4 0.0 0.3 10.6 0.0 1.4 1 MCM MCM P-loop domain 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 ABC_sub_bind ABC transporter substrate binding protein 0.23 12.2 0.1 0.52 11.0 0.1 1.6 2 FAD-SLDH Membrane bound FAD containing D-sorbitol dehydr Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 216.7 0.1 1.4e-67 1.8e-64 1 161 [. 13 173 .. 13 174 .. 0.99 Alignments for each domain: == domain 1 score: 216.7 bits; conditional E-value: 1.4e-67 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwlee 96 k+vl+GdsgvGKs+ll rf++n+F+ e++sTigv+f t++++vdgk++k qiwDTAGqer+ra+++ayyrga g+llvydi ++ ++env++wl+e FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE 108 89********************************************************************************************** PP Ras 97 ikrvaeenvpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 ++++a++n++i+lvGnk+Dl++ r+v+t+e++++a+++gl f+etSA +++nve af+++++ei+ FUN_000350-T1 109 LRDHADSNIVIMLVGNKSDLRHLRAVPTDEAKAFAEKNGLSFIETSALDSTNVEVAFHNILTEIY 173 *************************************************************9986 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 123.1 0.1 7.5e-39 9.6e-36 1 119 [] 13 127 .. 13 127 .. 0.91 Alignments for each domain: == domain 1 score: 123.1 bits; conditional E-value: 7.5e-39 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srsse 93 Kvvl+GdsgvGK+ ll+rf+++ef+ ++kstigv+f ++++ +++g k+ik +iWDtaGqer+r++++ yyr+a +a+lv+d + ++e FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSI-QVDG-------KTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDiakHLTYE 100 9************************************9987.4554.......789********************************8533388* PP Roc 94 nlkeWlkelkevagksp.vilvgnkiD 119 n+++Wlkel+++a++++ ++lvgnk D FUN_000350-T1 101 NVERWLKELRDHADSNIvIMLVGNKSD 127 ************997751569****98 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.6 0.1 5.5e-15 7e-12 15 141 .. 12 144 .. 4 180 .. 0.79 Alignments for each domain: == domain 1 score: 45.6 bits; conditional E-value: 5.5e-15 Arf 15 lrilllGLDnaGKtTilkklkleelvt.tiPTigfn..veevei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLk 105 ++++l+G + GK+ +l +++ +e++ + Tig + ++++++ k++k ++wD Gqe+ R + + Y++ + + v D a++ e+ ++ Lk FUN_000350-T1 12 FKVVLIGDSGVGKSNLLSRFTRNEFNLeSKSTIGVEfaTRSIQVdgKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLK 107 799********************9975388999865114445546699************************************************ PP Arf 106 alleeeelkeaallvlaNKqDlpe..alseaeikealg 141 +l ++ + +++++++++NK Dl++ a+ ++e k+ + FUN_000350-T1 108 ELRDHAD-SNIVIMLVGNKSDLRHlrAVPTDEAKAFAE 144 *876665.66777788*****98522565665554444 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 0.0 3.2e-10 4.1e-07 1 109 [. 13 119 .. 13 125 .. 0.64 2 ? -1.9 0.0 4 5.2e+03 8 18 .. 185 195 .. 165 197 .. 0.80 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 3.2e-10 MMR_HSR1 1 rvaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkg..kkielvDtpGliegaseee.gleraflaieeadlillvvd..aee.glt 90 +v+++G + vGKS L+ + t+++ + +++ + +++++++g k +++Dt+G e ++ +++a+ + a +llv d + + +++ FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGktIKAQIWDTAG-QE----RYrAITSAYYR--GAVGALLVYDiaK-HlTYE 100 699*****************9866555555555555555555444226789******.55....33366666663..4778888888642.32566 PP MMR_HSR1 91 eldeeleelleeekkpvil 109 ++++ l+el ++++ ++++ FUN_000350-T1 101 NVERWLKELRDHADSNIVI 119 6666666665444444333 PP == domain 2 score: -1.9 bits; conditional E-value: 4 MMR_HSR1 8 pNvGKStLina 18 pN+G S L n+ FUN_000350-T1 185 PNSGGSQLSNK 195 78888888876 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.1 5.2e-08 6.6e-05 48 179 .. 37 165 .. 10 178 .. 0.73 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 5.2e-08 GTP_EFTU 48 keErerGiTiksaavsfe..tkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveGvepqteevlrl.ark...lgvpiivviNKmDrvdea 137 + E + i ++ a+ s++ +k+ + ++ Dt G + + +++ ++ + ga+lv d+++ ++ + e ++ +r+ ++ i++v NK D+ FUN_000350-T1 37 NLESKSTIGVEFATRSIQvdGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKeLRDhadSNIVIMLVGNKSDLR--- 129 55666666666666666555999999********************************98555444444330333100455577777****99... PP GTP_EFTU 138 elkevveevkeellekvgekgekevpvvpgSalkgegvkell 179 l+ v ++ + + +ek + +++ +Sal+ +v+ + FUN_000350-T1 130 HLRAVPTDEAKAF----AEK--NGLSFIETSALDSTNVEVAF 165 9999999999888....333..35899******999998433 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 1.6e-05 0.021 109 129 .. 14 34 .. 10 72 .. 0.85 2 ! 8.2 0.1 0.0022 2.9 27 99 .. 88 163 .. 84 184 .. 0.76 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.6e-05 RsgA_GTPase 109 tvllGqSGvGKStLinallpe 129 +vl+G SGvGKS L+ +++ + FUN_000350-T1 14 VVLIGDSGVGKSNLLSRFTRN 34 69*************998874 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0022 RsgA_GTPase 27 vivvslkepefnlrlldrfLvla...eesgiepvivlnKiDlleeee.eleelkkeyealgyevllvsaktgeglee 99 ++v ++ ++++ + ++r L + +s+i +++v nK Dl + ++ ++e k+ +e+ g+ ++ +sa +++++e FUN_000350-T1 88 LLVYDIA-KHLTYENVERWLKELrdhADSNIVIMLVGNKSDLRHLRAvPTDEAKAFAEKNGLSFIETSALDSTNVEV 163 5666666.66777778888776611145677788888******999988999*****************99988874 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 4.5e-07 0.00058 8 128 .. 14 130 .. 13 131 .. 0.73 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 4.5e-07 AAA_22 8 lvltGesGtGKTtllrrlleqldee.ddsvvlvelpsst...spkdllrellralglelekelskeellaalqealkalaaravliiDEaqnls.e 98 +vl+G+sG+GK+ ll r++++ + ++s++ ve + + + k++ ++ g+ e ++a++ a + a+ a+l+ D a +l+ e FUN_000350-T1 14 VVLIGDSGVGKSNLLSRFTRNEFNLeSKSTIGVEFATRSiqvDGKTIKAQIWDTAGQ---------ERYRAITSAYYRGAVGALLVYDIAKHLTyE 100 589***************997544468888888888877545666666555555553.........444566666666666699999******865 PP AAA_22 99 elleeLrsllnlesekllqliLvGtp.elre 128 ++ ++L++l + +++++ + LvG +lr+ FUN_000350-T1 101 NVERWLKELRD-HADSNIVIMLVGNKsDLRH 130 55555566666.56699*******9988876 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 1.8e-05 0.023 3 54 .. 13 66 .. 11 100 .. 0.87 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1.8e-05 PduV-EutP 3 killiGkvgsGKttLtqalkgee..lkYkktqaiefsdaviDtPGeylenrkly 54 k++liG +g+GK L +++ +e l+ k+t +ef ++ i G+ ++ + + FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNEfnLESKSTIGVEFATRSIQVDGKTIKAQIWD 66 89***************9987652278899*************99999887664 PP >> ABC_tran ABC transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.1 2.2e-05 0.028 14 42 .. 14 44 .. 12 194 .. 0.80 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 2.2e-05 xxxxxxxxxxxxxxxxxxxxxxxx..xxxxx RF ABC_tran 14 lalvGenGaGKStLlkllagllkp..teGei 42 ++l+G +G+GKS Ll+ +++++ + ++ +i FUN_000350-T1 14 VVLIGDSGVGKSNLLSRFTRNEFNleSKSTI 44 89****************9998775533333 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.1 3.1e-05 0.04 27 47 .. 14 37 .. 13 173 .. 0.72 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 3.1e-05 AAA_16 27 vlvsGeaGvGKSalvrellr...a 47 v+++G++GvGKS l+++++r FUN_000350-T1 14 VVLIGDSGVGKSNLLSRFTRnefN 37 89***************9974433 PP >> FeoB_N Ferrous iron transport protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 8e-05 0.1 2 59 .. 13 72 .. 12 168 .. 0.68 2 ? -3.4 0.0 6.6 8.4e+03 8 20 .. 184 196 .. 181 197 .. 0.83 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 8e-05 FeoB_N 2 tvalvGnpnvGkttlfnaltgakqkvgNwpGvtvekkegklklkekei..elvDlPGiYs 59 +v+l+G vGk+ l+ + t + + + + ve ++ ++++++k+i ++ D+ G FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIkaQIWDTAGQER 72 79*********************************9999999998655227889888644 PP == domain 2 score: -3.4 bits; conditional E-value: 6.6 FeoB_N 8 npnvGkttlfnal 20 pn+G + l n++ FUN_000350-T1 184 SPNSGGSQLSNKM 196 699**99999875 PP >> NTPase_1 NTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.1 6.6e-05 0.084 1 93 [. 13 106 .. 13 124 .. 0.79 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 6.6e-05 NTPase_1 1 kifiTGepGvGKtTlvekvaek...lkekgvkvgGfyteevreggkrigFkivdlasgeegiLarveakseprvgkyvvnveeleevavealrkal 93 k+++ G +GvGK+ l+++ ++ l++k f t+ ++ +gk i +i d g+e + a ++a + vg + v + +++++ e++++ l FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNefnLESKSTIGVEFATRSIQVDGKTIKAQIWDT-AGQERYRAITSAYYRGAVGALLVY-DIAKHLTYENVERWL 106 58899************98874333666655555699******************.777777787777888899999888.778888888877765 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 5.3e-05 0.067 1 123 [. 13 128 .. 13 175 .. 0.65 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.3e-05 Gtr1_RagA 1 kvLLmGksksGKsSirsviFsnyspkdt.lrlgatidveksevrflgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedl 95 kv+L+G s+ GKs + s +n + ++g+ + +v + ++ ++wd Gqe++ + + + v++L+ v D+ ++ + FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTRNEFNLESkSTIGVEFATRSIQVD-GKTIKAQIWDTAGQERYRAIT----SAYYRGAVGALL-VYDIAKH---LTY 99 89************999766665554441456666666666663.5679***********987766....344445677775.7788833...344 PP Gtr1_RagA 96 arlketlealsevspeakvfvli.hKvDl 123 +++++ l++l+++ v +l+ +K Dl FUN_000350-T1 100 ENVERWLKELRDHADSNIVIMLVgNKSDL 128 55566666666665555555555356665 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.0002 0.26 38 59 .. 14 35 .. 6 56 .. 0.87 2 ? -0.2 0.0 0.65 8.3e+02 137 170 .. 100 132 .. 58 139 .. 0.70 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0002 TniB 38 lllvGdsnnGKstivekFarlh 59 ++l+Gds +GKs ++++F+r++ FUN_000350-T1 14 VVLIGDSGVGKSNLLSRFTRNE 35 789****************986 PP == domain 2 score: -0.2 bits; conditional E-value: 0.65 TniB 137 rkqreflnalkslgnelkipivlvGteealralk 170 ++ + l+ l++ + + +i i lvG ++ lr+l+ FUN_000350-T1 100 ENVERWLKELRD-HADSNIVIMLVGNKSDLRHLR 132 444444444444.334578888899888887776 PP >> AAA_14 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.1 0.00018 0.24 5 99 .. 14 126 .. 13 153 .. 0.67 2 ? -3.3 0.0 9.3 1.2e+04 105 122 .. 187 204 .. 171 205 .. 0.73 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00018 AAA_14 5 lvitGpRqvGKTtllkqlikell..ekesilylnlddprlreladee...........llelllellke......ekkllflDEiqrv..peweka 79 +v++G +vGK+ ll ++ ++++ e++s++ +++ + + + ++ +++++ + ll+ D ++++ +++e++ FUN_000350-T1 14 VVLIGDSGVGKSNLLSRFTRNEFnlESKSTIGVEFATRSIQVDGKTIkaqiwdtagqeRYRAIT----SayyrgaVGALLVYDIAKHLtyENVERW 105 68899999************99999889999999998777443322111232233323333344....1444466456688887776444899999 PP AAA_14 80 lkrlvdeg.knlkvvltGSss 99 lk+l+d+ +n+ ++l G +s FUN_000350-T1 106 LKELRDHAdSNIVIMLVGNKS 126 999999764666666666544 PP == domain 2 score: -3.3 bits; conditional E-value: 9.3 AAA_14 105 elaeslagrveelellPl 122 + ++l+ +++++ l Pl FUN_000350-T1 187 SGGSQLSNKMDTIPLPPL 204 456778888888888887 PP >> DUF3289 Protein of unknown function (DUF3289) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.00013 0.16 84 147 .. 70 134 .. 29 165 .. 0.76 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00013 DUF3289 84 DefrslskqfafsGkyrs.likelinhlqygnGapfsselLdsalkekilsetssdssllkiqka 147 e ++ ++ ++ G l+ ++ +hl y+n + + +el d+a + ++ ++s l +++++ FUN_000350-T1 70 QERYRAITSAYYRGAVGAlLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAV 134 5555555667778887651678999*************************999999999988875 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00026 0.33 4 39 .. 13 55 .. 12 76 .. 0.73 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00026 AAA_24 4 kvliyGpsgiGKTtlaksl.......pkplvldtekGsksleg 39 kv+++G+sg+GK+ l++++ + + +e + s+++ FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFtrnefnlESKSTIGVEFATRSIQV 55 89****************9766555555555555555555555 PP >> MCM MCM P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.00024 0.3 59 79 .. 13 33 .. 4 64 .. 0.83 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00024 MCM 59 nvllvgdpgtaKsqlLkyvek 79 +v+l+gd+g++Ks+lL++ ++ FUN_000350-T1 13 KVVLIGDSGVGKSNLLSRFTR 33 699*************98764 PP >> ABC_sub_bind ABC transporter substrate binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00023 0.29 150 192 .. 137 179 .. 118 201 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00023 ABC_sub_bind 150 ellkklakkaglklveaavkkvkdvesavkalkekvdaivilt 192 + k+ a+k+gl+ +e ++ ++ +ve+a +++ + + iv + FUN_000350-T1 137 DEAKAFAEKNGLSFIETSALDSTNVEVAFHNILTEIYHIVSQK 179 57899****************************9999998765 PP >> FAD-SLDH Membrane bound FAD containing D-sorbitol dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.00041 0.52 96 135 .. 61 101 .. 24 105 .. 0.81 2 ? -2.5 0.0 5.9 7.5e+03 70 92 .. 162 184 .. 153 192 .. 0.77 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00041 FAD-SLDH 96 aasavaedsalkalarkiisaWYlGvvge...gddakvvaYes 135 +a+ + d a ++ +r+i sa+Y+G vg+ d ak ++Ye+ FUN_000350-T1 61 KAQ--IWDTAGQERYRAITSAYYRGAVGAllvYDIAKHLTYEN 101 444..778889999*************9988888899999987 PP == domain 2 score: -2.5 bits; conditional E-value: 5.9 FAD-SLDH 70 dpefeaqleaLlalleqqklkdv 92 + +f++ l++++++++q++++d+ FUN_000350-T1 162 EVAFHNILTEIYHIVSQKQITDS 184 45677888888888888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (218 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 721 (0.0282247); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2156.65 // Query: FUN_000351-T1 [L=1199] Description: FUN_000351 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-104 343.5 28.3 2.4e-16 60.6 0.0 8.8 9 Ank_2 Ankyrin repeats (3 copies) 2e-84 273.1 23.4 1.3e-07 32.0 0.1 15.6 16 Ank Ankyrin repeat 4e-65 207.7 9.4 0.0033 18.3 0.0 16.5 16 Ank_3 Ankyrin repeat 1.2e-59 197.4 11.4 4.1e-07 30.6 0.0 12.6 14 Ank_4 Ankyrin repeats (many copies) 2.8e-51 171.4 20.3 1.3e-06 29.1 0.2 13.7 14 Ank_5 Ankyrin repeats (many copies) 2.4e-18 66.8 3.4 0.00034 20.9 0.1 7.3 7 Ank_KRIT1 KRIT1 ankyrin-repeats domain 8.4e-14 51.8 22.1 1.2e-13 51.3 22.1 1.2 1 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 Nucleopor_Nup85 Nup85 Nucleoporin 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 TSKS Testis-specific serine kinase substrate 0.12 11.8 2.0 0.28 10.6 2.0 1.5 1 IFT57 Intra-flagellar transport protein 57 1.2 10.0 2.9 14 6.6 0.2 3.1 3 TilS TilS substrate binding domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.5 0.1 4.5e-14 1e-10 27 90 .] 155 225 .. 128 225 .. 0.78 2 ! 41.0 1.9 1.3e-13 3e-10 19 88 .. 218 293 .. 217 294 .. 0.86 3 ! 29.7 0.1 4.3e-10 9.9e-07 9 87 .. 277 369 .. 275 371 .. 0.78 4 ! 36.8 0.0 2.6e-12 6e-09 1 82 [. 302 398 .. 302 405 .. 0.80 5 ! 58.3 0.0 5.2e-19 1.2e-15 1 90 [] 346 442 .. 346 442 .. 0.89 6 ! 48.3 0.0 6.9e-16 1.6e-12 24 90 .] 407 475 .. 401 475 .. 0.93 7 ! 59.7 0.2 1.9e-19 4.5e-16 1 90 [] 449 544 .. 449 544 .. 0.87 8 ! 60.6 0.0 1e-19 2.4e-16 1 88 [. 551 643 .. 551 645 .. 0.86 9 ! 50.7 0.7 1.2e-16 2.8e-13 1 82 [. 618 704 .. 618 707 .. 0.90 Alignments for each domain: == domain 1 score: 42.5 bits; conditional E-value: 4.5e-14 Ank_2 27 k....ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 n++ Lh ++g+++ +++Ll++ +++ d++g+taLh++++ g++++vk+Ll + ad+n+kd FUN_000351-T1 155 GeygdNEKDTLHTLSRKGNIQEISALLSQQnEEIDkrDSYGKTALHCSVSAGQVDTVKYLLYNHADPNIKD 225 1444578999**********99*999995323345569***********************999****998 PP == domain 2 score: 41.0 bits; conditional E-value: 1.3e-13 Ank_2 19 gadanlqdkngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaes...ghleivklLlekgadina 88 +ad+n++d ++e +Lh+A+++g++e+v++Ll+h +vn +n +t+Lh Aa + +ei++ Ll++ a+++a FUN_000351-T1 218 HADPNIKDHREEAPLHVAVRTGNVEVVEALLNHTaTNVNieGRNRYTPLHNAAHLehrNAVEICQKLLDCRANVTA 293 799*****************************976567776799*********88666668999999988888875 PP == domain 3 score: 29.7 bits; conditional E-value: 4.3e-10 Ank_2 9 nlelvklLlegadanlqdk..ngetaLhlAaknghleivklLlehgad...............vndnngrtaLhyAaesghleivklLlekgadin 87 e+++ Ll ++ an++ + +t+L +Aa++g++ei+ l+ ++ + v d +g + Lh+A+ sg l++vkl le+g++++ FUN_000351-T1 277 AVEICQKLL-DCRANVTARgvDHMTPLSVAAQKGSAEIMALFFKKC-SetqrgaklqqehlygV-DFEGGSLLHLAVDSGVLKAVKLCLEYGCSVT 369 469******.666665555679*****************9999952.23445555654444333.588******************999***9987 PP == domain 4 score: 36.8 bits; conditional E-value: 2.6e-12 Ank_2 1 LmlAakngnlelvklLl.eg....adanlqdk.........ngetaLhlAaknghleivklLlehgadvn...dnngrtaLhyAaesghleivklL 79 L +Aa++g+ e++ l++ + a+l + +g + LhlA+ +g l++vkl le+g++v ++g t++h+A++ g lei+k L FUN_000351-T1 302 LSVAAQKGSAEIMALFFkKCsetqRGAKL--QqehlygvdfEGGSLLHLAVDSGVLKAVKLCLEYGCSVTavkRRDGGTPIHLACRLGALEILKCL 395 6789999*999999999622233312233..13477888899***********************98855565699******************** PP Ank_2 80 lek 82 e+ FUN_000351-T1 396 YEH 398 986 PP == domain 5 score: 58.3 bits; conditional E-value: 5.2e-19 Ank_2 1 LmlAakngnlelvklLl.egadanlqdk.ngetaLhlAaknghleivklLlehg.advn....dnngrtaLhyAaesghleivklLlekgadinak 89 L+lA+ +g l++vkl l +g+++ ++ +g t++hlA++ g lei+k+L eh+ a+ + d++ +t+Lh +++ +h+ +v++L+++g+d+n + FUN_000351-T1 346 LHLAVDSGVLKAVKLCLeYGCSVTAVKRrDGGTPIHLACRLGALEILKCLYEHDpAAFErtlvDKEDMTPLHRCSMFNHVGVVQFLVDHGVDLNPR 441 8*******99*******999999944445************************76443345667*****************************988 PP Ank_2 90 d 90 d FUN_000351-T1 442 D 442 7 PP == domain 6 score: 48.3 bits; conditional E-value: 6.9e-16 Ank_2 24 lqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+dk+ +t+Lh + + +h+ +v++L++hg+d+n d++ +t+L +Aa +g+ +v lLle+gad++ +d FUN_000351-T1 407 LVDKEDMTPLHRCSMFNHVGVVQFLVDHGVDLNprDRERCTPLLLAAAHGCSAVVSLLLENGADVTCED 475 567788*************************99999*****************************9876 PP == domain 7 score: 59.7 bits; conditional E-value: 1.9e-19 Ank_2 1 LmlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLle....hgad...vn..dnngrtaLhyAaesghleivklLlekgadi 86 L lAa++g + +v lLl +gad+ ++d++ +taLh+A+ ++ ++++ Ll+ + + vn d++g taLhyAa+ g l+ v lLl++gad+ FUN_000351-T1 449 LLLAAAHGCSAVVSLLLeNGADVTCEDEKRRTALHWAVGQD--KTIERLLKdvqvQ--ElklVNqrDSTGSTALHYAAQGGFLKSVLLLLKNGADP 540 679*****999999999***********************9..8898888755442..144455669****************************9 PP Ank_2 87 nakd 90 +k+ FUN_000351-T1 541 SLKN 544 9875 PP == domain 8 score: 60.6 bits; conditional E-value: 1e-19 Ank_2 1 LmlAakngnlelvklLlegadanlqdk...ngetaLhlAaknghleivklLlehgadvn.dnngrtaLhyAaesghleivklLlek.gadina 88 L+lAa++g l +vk L+eg ++++++ t+LhlAa+ng+ +vk+Ll+ ga ++ d +grt+Lh+Aa +g+l+ v+l++++ +in+ FUN_000351-T1 551 LHLAASYGWLPIVKKLMEGRQTRMMNVgnlSDLTPLHLAACNGQDRVVKFLLDRGATIErDTDGRTPLHFAAAKGSLKSVQLICSScPNSINV 643 8*******99*******887766666566788*********************99878889*********************99543446665 PP == domain 9 score: 50.7 bits; conditional E-value: 1.2e-16 Ank_2 1 LmlAakngnlelvklLl..egadanlqdk.ngetaLhlAaknghleivklLlehg.advn.dnngrtaLhyAaesghleivklLlek 82 L++Aa++g+l+ v+l+ +++++n++d+ + +taLhlAakngh ++v ++l+h+ +v + ++++aL +A+e g +++v ++e+ FUN_000351-T1 618 LHFAAAKGSLKSVQLICssCPNSINVEDNkDQDTALHLAAKNGHPDVVTYFLSHEsQNVTyNGYNQNALDVAIEAGKEQVVLAIAEH 704 8***************9999999998888899*********************975445577999***************9988765 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 2.5 5.8e+03 6 32 .. 165 192 .. 165 193 .. 0.78 2 ! 32.0 0.1 5.6e-11 1.3e-07 1 32 [. 194 225 .. 194 226 .. 0.94 3 ! 23.3 0.1 3.4e-08 7.8e-05 5 31 .. 231 258 .. 228 260 .. 0.87 4 ! 18.6 0.4 1e-06 0.0023 2 31 .. 262 294 .. 261 296 .. 0.82 5 ! 6.2 0.0 0.0091 21 2 20 .. 298 316 .. 297 323 .. 0.86 6 ! 11.1 0.0 0.00026 0.61 3 31 .. 343 371 .. 341 373 .. 0.88 7 ! 14.9 0.1 1.5e-05 0.036 1 24 [. 375 398 .. 375 404 .. 0.87 8 ! 24.3 0.0 1.6e-08 3.7e-05 3 32 .. 413 442 .. 411 443 .. 0.93 9 ! 22.9 0.1 4.4e-08 0.0001 3 32 .. 446 475 .. 444 476 .. 0.92 10 ! 8.7 0.0 0.0015 3.4 3 23 .. 479 497 .. 477 504 .. 0.81 11 ! 26.1 0.0 4.3e-09 9.9e-06 2 32 .. 514 544 .. 513 545 .. 0.94 12 ! 16.0 0.0 6.7e-06 0.016 3 25 .. 548 569 .. 546 576 .. 0.90 13 ! 26.0 0.0 4.5e-09 1e-05 3 28 .. 583 608 .. 581 612 .. 0.89 14 ! 20.2 0.0 3.1e-07 0.00072 1 31 [. 613 644 .. 613 646 .. 0.76 15 ! 22.5 0.0 6.1e-08 0.00014 2 24 .. 649 671 .. 648 679 .. 0.82 16 ? -2.3 0.0 4.7 1.1e+04 3 18 .. 683 698 .. 681 701 .. 0.85 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.5 Ank 6 LHlAaraghlevvklLL.khGAdvnard 32 LH +r+g+++ + LL +++ ++ rd FUN_000351-T1 165 LHTLSRKGNIQEISALLsQQNEEIDKRD 192 7866889999999999966678888887 PP == domain 2 score: 32.0 bits; conditional E-value: 5.6e-11 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G T+LH+ ++ag++++vk+LL+++Ad+n++d FUN_000351-T1 194 YGKTALHCSVSAGQVDTVKYLLYNHADPNIKD 225 69********************779******9 PP == domain 3 score: 23.3 bits; conditional E-value: 3.4e-08 Ank 5 PLHlAaraghlevvklLLkh.GAdvnar 31 PLH+A+r g++evv+ LL+h +vn+ FUN_000351-T1 231 PLHVAVRTGNVEVVEALLNHtATNVNIE 258 9*****************7734799985 PP == domain 4 score: 18.6 bits; conditional E-value: 1e-06 Ank 2 GnTPLHlAaragh...levvklLLkhGAdvnar 31 +TPLH Aa+ h +e+++ LL+ A+v ar FUN_000351-T1 262 RYTPLHNAAHLEHrnaVEICQKLLDCRANVTAR 294 58*******5555556********778***997 PP == domain 5 score: 6.2 bits; conditional E-value: 0.0091 Ank 2 GnTPLHlAaraghlevvkl 20 +TPL +Aa++g+ e++ l FUN_000351-T1 298 HMTPLSVAAQKGSAEIMAL 316 68***********999876 PP == domain 6 score: 11.1 bits; conditional E-value: 0.00026 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnar 31 + LHlA+ g l+ vkl L++G++v a+ FUN_000351-T1 343 GSLLHLAVDSGVLKAVKLCLEYGCSVTAV 371 578*****99**********88***9886 PP == domain 7 score: 14.9 bits; conditional E-value: 1.5e-05 Ank 1 dGnTPLHlAaraghlevvklLLkh 24 dG TP+HlA+r g le++k L +h FUN_000351-T1 375 DGGTPIHLACRLGALEILKCLYEH 398 688*****************9854 PP == domain 8 score: 24.3 bits; conditional E-value: 1.6e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH +++ +h+ vv++L++hG+d+n rd FUN_000351-T1 413 MTPLHRCSMFNHVGVVQFLVDHGVDLNPRD 442 8*****999***********99*****998 PP == domain 9 score: 22.9 bits; conditional E-value: 4.4e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPL lAa +g+ vv lLL++GAdv + d FUN_000351-T1 446 CTPLLLAAAHGCSAVVSLLLENGADVTCED 475 8*******99**********98****9877 PP == domain 10 score: 8.7 bits; conditional E-value: 0.0015 Ank 3 nTPLHlAaraghlevvklLLk 23 +T+LH+A+ g+ ++++ LLk FUN_000351-T1 479 RTALHWAV--GQDKTIERLLK 497 8*****99..66679999994 PP == domain 11 score: 26.1 bits; conditional E-value: 4.3e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G T+LH+Aa+ g l+ v lLLk+GAd+ +++ FUN_000351-T1 514 GSTALHYAAQGGFLKSVLLLLKNGADPSLKN 544 99*******************98****9998 PP == domain 12 score: 16.0 bits; conditional E-value: 6.7e-06 Ank 3 nTPLHlAaraghlevvklLLkhG 25 TPLHlAa++g l +vk L + G FUN_000351-T1 548 ETPLHLAASYGWLPIVKKLME-G 569 6****************9983.5 PP == domain 13 score: 26.0 bits; conditional E-value: 4.5e-09 Ank 3 nTPLHlAaraghlevvklLLkhGAdv 28 TPLHlAa++g+ vvk+LL++GA + FUN_000351-T1 583 LTPLHLAACNGQDRVVKFLLDRGATI 608 6*******************889976 PP == domain 14 score: 20.2 bits; conditional E-value: 3.1e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhG.Advnar 31 dG+TPLH Aa +g+l+ v+l++++ ++n+ FUN_000351-T1 613 DGRTPLHFAAAKGSLKSVQLICSSCpNSINVE 644 8******99999*******9994332235655 PP == domain 15 score: 22.5 bits; conditional E-value: 6.1e-08 Ank 2 GnTPLHlAaraghlevvklLLkh 24 +T+LHlAa++gh++vv + L+h FUN_000351-T1 649 QDTALHLAAKNGHPDVVTYFLSH 671 68*******************65 PP == domain 16 score: -2.3 bits; conditional E-value: 4.7 Ank 3 nTPLHlAaraghlevv 18 + +L +A++ag ++vv FUN_000351-T1 683 QNALDVAIEAGKEQVV 698 7899****99999998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.7 1.6e+03 6 30 .. 165 189 .. 165 190 .. 0.88 2 ! 12.1 0.0 0.00015 0.34 1 31 [] 194 223 .. 194 223 .. 0.94 3 ! 17.0 0.0 3.8e-06 0.0088 5 30 .. 231 256 .. 228 257 .. 0.89 4 ! 9.0 0.1 0.0015 3.6 2 29 .. 262 291 .. 261 293 .. 0.83 5 ? 6.3 0.0 0.011 26 2 25 .. 298 321 .. 297 325 .. 0.87 6 ! 13.6 0.0 4.9e-05 0.11 2 29 .. 342 368 .. 341 370 .. 0.92 7 ! 16.6 0.0 4.9e-06 0.011 1 27 [. 375 401 .. 375 404 .. 0.88 8 ! 18.3 0.0 1.4e-06 0.0033 3 30 .. 413 439 .. 411 439 .. 0.95 9 ! 18.2 0.1 1.5e-06 0.0035 3 30 .. 446 472 .. 444 473 .. 0.93 10 ? 5.2 0.0 0.026 60 3 23 .. 479 497 .. 477 502 .. 0.84 11 ! 14.5 0.0 2.3e-05 0.054 2 30 .. 514 541 .. 513 542 .. 0.93 12 ! 14.8 0.0 1.9e-05 0.044 3 23 .. 548 568 .. 546 572 .. 0.91 13 ! 14.3 0.0 2.8e-05 0.065 4 29 .. 584 608 .. 582 610 .. 0.93 14 ! 14.7 0.0 2.1e-05 0.049 1 30 [. 613 642 .. 613 643 .. 0.93 15 ! 15.2 0.0 1.4e-05 0.032 3 24 .. 650 671 .. 648 677 .. 0.87 16 ? 1.3 0.0 0.5 1.2e+03 1 24 [. 681 704 .. 681 707 .. 0.88 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.7 Ank_3 6 LhlAarngrleivklLleklgadin 30 Lh+ r g+++ + +Ll +++ +i+ FUN_000351-T1 165 LHTLSRKGNIQEISALLSQQNEEID 189 89********88*****98888776 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00015 Ank_3 1 dgntpLhlAarngrleivklLleklgadina 31 +g t+Lh+ ++ g+++ vk+Ll ++ad+n+ FUN_000351-T1 194 YGKTALHCSVSAGQVDTVKYLLY-NHADPNI 223 799*******************9.9999985 PP == domain 3 score: 17.0 bits; conditional E-value: 3.8e-06 Ank_3 5 pLhlAarngrleivklLleklgadin 30 pLh+A+r g++e+v++Ll++ ++n FUN_000351-T1 231 PLHVAVRTGNVEVVEALLNHTATNVN 256 9******************8777777 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0015 Ank_3 2 gntpLhlAarngrl...eivklLleklgadi 29 +tpLh Aa+ + ei++ Ll+ + a++ FUN_000351-T1 262 RYTPLHNAAHLEHRnavEICQKLLD-CRANV 291 69************77778888888.88876 PP == domain 5 score: 6.3 bits; conditional E-value: 0.011 Ank_3 2 gntpLhlAarngrleivklLlekl 25 ++tpL +Aa g+ ei+ l+++k+ FUN_000351-T1 298 HMTPLSVAAQKGSAEIMALFFKKC 321 78*************999998855 PP == domain 6 score: 13.6 bits; conditional E-value: 4.9e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g ++LhlA+ +g l++vkl+le +g+++ FUN_000351-T1 342 GGSLLHLAVDSGVLKAVKLCLE-YGCSV 368 789*******************.**987 PP == domain 7 score: 16.6 bits; conditional E-value: 4.9e-06 Ank_3 1 dgntpLhlAarngrleivklLleklga 27 dg tp+hlA+r g lei+k+L e+ +a FUN_000351-T1 375 DGGTPIHLACRLGALEILKCLYEHDPA 401 689******************997665 PP == domain 8 score: 18.3 bits; conditional E-value: 1.4e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +tpLh + +++++ +v++L++ +g+d+n FUN_000351-T1 413 MTPLHRCSMFNHVGVVQFLVD-HGVDLN 439 7********************.****98 PP == domain 9 score: 18.2 bits; conditional E-value: 1.5e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +tpL lAa +g+ +v lLle +gad+ FUN_000351-T1 446 CTPLLLAAAHGCSAVVSLLLE-NGADVT 472 8********************.****85 PP == domain 10 score: 5.2 bits; conditional E-value: 0.026 Ank_3 3 ntpLhlAarngrleivklLle 23 +t+Lh+A+ ++ ++ Ll+ FUN_000351-T1 479 RTALHWAVGQDKT--IERLLK 497 8********9999..888877 PP == domain 11 score: 14.5 bits; conditional E-value: 2.3e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 g t+Lh+Aa g l+ v lLl+ +gad+ FUN_000351-T1 514 GSTALHYAAQGGFLKSVLLLLK-NGADPS 541 88************99******.****85 PP == domain 12 score: 14.8 bits; conditional E-value: 1.9e-05 Ank_3 3 ntpLhlAarngrleivklLle 23 +tpLhlAa++g l+ivk L e FUN_000351-T1 548 ETPLHLAASYGWLPIVKKLME 568 7****************9998 PP == domain 13 score: 14.3 bits; conditional E-value: 2.8e-05 Ank_3 4 tpLhlAarngrleivklLleklgadi 29 tpLhlAa ng+ +vk+Ll+ +ga i FUN_000351-T1 584 TPLHLAACNGQDRVVKFLLD-RGATI 608 9*******************.**988 PP == domain 14 score: 14.7 bits; conditional E-value: 2.1e-05 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 dg+tpLh+Aa g+l+ v+l++ ++ +in FUN_000351-T1 613 DGRTPLHFAAAKGSLKSVQLICSSCPNSIN 642 79*************99*****99999988 PP == domain 15 score: 15.2 bits; conditional E-value: 1.4e-05 Ank_3 3 ntpLhlAarngrleivklLlek 24 t+LhlAa+ng++++v ++l + FUN_000351-T1 650 DTALHLAAKNGHPDVVTYFLSH 671 69*****************984 PP == domain 16 score: 1.3 bits; conditional E-value: 0.5 Ank_3 1 dgntpLhlAarngrleivklLlek 24 +++++L +A++ g+ ++v ++ e+ FUN_000351-T1 681 YNQNALDVAIEAGKEQVVLAIAEH 704 6899************99999885 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 3.9e-10 9.1e-07 1 50 [] 165 215 .. 165 215 .. 0.94 2 ! 30.6 0.0 1.8e-10 4.1e-07 7 50 .] 205 248 .. 203 248 .. 0.96 3 ? 4.4 0.1 0.032 73 30 50 .] 262 285 .. 252 285 .. 0.66 4 ! 9.7 0.2 0.00068 1.6 1 48 [. 266 316 .. 266 318 .. 0.92 5 ! 25.1 0.0 9.7e-09 2.3e-05 1 49 [. 346 395 .. 346 396 .. 0.97 6 ! 18.3 0.0 1.4e-06 0.0032 26 50 .] 408 432 .. 402 432 .. 0.91 7 ! 28.3 0.1 9.3e-10 2.2e-06 1 41 [. 416 456 .. 416 461 .. 0.97 8 ! 16.9 0.1 3.7e-06 0.0087 4 38 .. 452 486 .. 451 491 .. 0.94 9 ! 13.9 0.0 3.2e-05 0.075 11 50 .] 490 534 .. 487 534 .. 0.75 10 ! 22.3 0.0 7.6e-08 0.00018 1 49 [. 518 566 .. 518 567 .. 0.95 11 ! 6.6 0.0 0.0067 15 27 50 .] 579 602 .. 576 602 .. 0.90 12 ! 24.0 0.0 2.1e-08 4.8e-05 1 48 [. 586 632 .. 586 633 .. 0.89 13 ! 18.2 0.0 1.4e-06 0.0032 27 50 .] 646 669 .. 638 669 .. 0.88 14 ? -0.2 0.0 0.86 2e+03 1 19 [. 686 704 .. 675 723 .. 0.67 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 3.9e-10 Ank_4 1 lhaAaksghlellklLlen.gadinatdgngetaLhfAasngnlevlklLl 50 lh + +g+++ + Ll+ +i+++d +g taLh+ +s g+++ +k+Ll FUN_000351-T1 165 LHTLSRKGNIQEISALLSQqNEEIDKRDSYGKTALHCSVSAGQVDTVKYLL 215 799999***********654999***************************8 PP == domain 2 score: 30.6 bits; conditional E-value: 1.8e-10 Ank_4 7 sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 +g+++++k+Ll n ad+n d+ e +Lh A++ gn+ev++ Ll FUN_000351-T1 205 AGQVDTVKYLLYNHADPNIKDHREEAPLHVAVRTGNVEVVEALL 248 799**************************************997 PP == domain 3 score: 4.4 bits; conditional E-value: 0.032 Ank_4 30 getaLhfAasngn...levlklLl 50 +t+Lh+Aa+ ++ +e+++ Ll FUN_000351-T1 262 RYTPLHNAAHLEHrnaVEICQKLL 285 369******655533477777775 PP == domain 4 score: 9.7 bits; conditional E-value: 0.00068 Ank_4 1 lhaAak...sghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 lh Aa+ ++ +e+++ Ll+ +a++ a+ + +t+L Aa++g+ e+ l FUN_000351-T1 266 LHNAAHlehRNAVEICQKLLDCRANVTARGVDHMTPLSVAAQKGSAEIMAL 316 799999999********************889************9998765 PP == domain 5 score: 25.1 bits; conditional E-value: 9.7e-09 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklL 49 lh A+ sg l+++kl+le+g ++ a+ ++g t++h A++ g le+lk+L FUN_000351-T1 346 LHLAVDSGVLKAVKLCLEYGCSVTAVkRRDGGTPIHLACRLGALEILKCL 395 799999******************************************98 PP == domain 6 score: 18.3 bits; conditional E-value: 1.4e-06 Ank_4 26 tdgngetaLhfAasngnlevlklLl 50 +d++++t+Lh++++++++ v+++L+ FUN_000351-T1 408 VDKEDMTPLHRCSMFNHVGVVQFLV 432 399********************96 PP == domain 7 score: 28.3 bits; conditional E-value: 9.3e-10 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasng 41 lh++ +++h+ ++++L+++g+d+n +d++ t+L Aa++g FUN_000351-T1 416 LHRCSMFNHVGVVQFLVDHGVDLNPRDRERCTPLLLAAAHG 456 8**************************************99 PP == domain 8 score: 16.9 bits; conditional E-value: 3.7e-06 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAa 38 Aa++g+ ++ lLlengad+ + d+ +taLh+A+ FUN_000351-T1 452 AAAHGCSAVVSLLLENGADVTCEDEKRRTALHWAV 486 899****************9999***********8 PP == domain 9 score: 13.9 bits; conditional E-value: 3.2e-05 Ank_4 11 ellklLlengad......inatdgngetaLhfAasngnlevlklLl 50 +++++Ll+ ++ +n +d g taLh+Aa++g l+ + lLl FUN_000351-T1 490 KTIERLLKD-VQvqelklVNQRDSTGSTALHYAAQGGFLKSVLLLL 534 566777743.22336666888899**************99999886 PP == domain 10 score: 22.3 bits; conditional E-value: 7.6e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+Aa g l+ + lLl+ngad+ + et+Lh Aas g l ++k L FUN_000351-T1 518 LHYAAQGGFLKSVLLLLKNGADPSLKNTKLETPLHLAASYGWLPIVKKL 566 8***************************************988888876 PP == domain 11 score: 6.6 bits; conditional E-value: 0.0067 Ank_4 27 dgngetaLhfAasngnlevlklLl 50 + ++ t+Lh Aa ng+ +v+k+Ll FUN_000351-T1 579 NLSDLTPLHLAACNGQDRVVKFLL 602 56789*****************97 PP == domain 12 score: 24.0 bits; conditional E-value: 2.1e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 lh Aa g+ +++k+Ll+ ga ++d +g+t+LhfAa++g+l+ ++l FUN_000351-T1 586 LHLAACNGQDRVVKFLLDRGAT-IERDTDGRTPLHFAAAKGSLKSVQL 632 6788889************985.567999*************999986 PP == domain 13 score: 18.2 bits; conditional E-value: 1.4e-06 Ank_4 27 dgngetaLhfAasngnlevlklLl 50 +++++taLh Aa+ng+++v+ ++l FUN_000351-T1 646 NKDQDTALHLAAKNGHPDVVTYFL 669 899*******************97 PP == domain 14 score: -0.2 bits; conditional E-value: 0.86 Ank_4 1 lhaAaksghlellklLlen 19 l++A+++g+++++ + e+ FUN_000351-T1 686 LDVAIEAGKEQVVLAIAEH 704 5566667777777666666 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 1.3e-07 0.0003 4 56 .] 183 235 .. 180 235 .. 0.91 2 ! 16.2 0.2 6.4e-06 0.015 6 37 .. 218 249 .. 216 253 .. 0.91 3 ! 12.5 1.1 9.4e-05 0.22 1 36 [. 247 285 .. 247 297 .. 0.75 4 ! 9.0 0.0 0.0011 2.6 2 36 .. 285 318 .. 284 349 .. 0.83 5 ? 3.1 0.0 0.084 2e+02 14 44 .. 342 370 .. 330 374 .. 0.84 6 ! 12.4 0.0 9.6e-05 0.22 11 44 .. 373 404 .. 362 407 .. 0.79 7 ! 16.2 0.0 6.2e-06 0.014 13 53 .. 409 449 .. 406 449 .. 0.95 8 ! 29.1 0.2 5.7e-10 1.3e-06 1 54 [. 431 483 .. 431 485 .. 0.95 9 ! 26.8 0.0 3e-09 7.1e-06 9 56 .] 507 554 .. 502 554 .. 0.94 10 ! 21.7 0.0 1.2e-07 0.00027 1 37 [. 533 568 .. 533 576 .. 0.91 11 ! 20.2 0.0 3.4e-07 0.00079 12 56 .] 578 621 .. 572 621 .. 0.88 12 ! 11.5 0.0 0.00019 0.43 13 36 .. 611 634 .. 605 640 .. 0.84 13 ! 25.0 0.2 1.1e-08 2.5e-05 8 56 .] 640 689 .. 636 689 .. 0.87 14 ? -3.5 0.0 9.6 2.2e+04 19 31 .. 778 790 .. 776 791 .. 0.83 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.3e-07 Ank_5 4 ngpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 ++ ++ +d +g t+Lh +++g + v++Ll n++d+n+kd + + pl++A FUN_000351-T1 183 QQNEEIDKRDSYGKTALHCSVSAGQVDTVKYLLYNHADPNIKDHREEAPLHVA 235 456788999999**************************************998 PP == domain 2 score: 16.2 bits; conditional E-value: 6.4e-06 Ank_5 6 padlnrldgegytpLhvAakygaleivrlLla 37 +ad+n++d + + pLhvA+++g+ e+v+ Ll+ FUN_000351-T1 218 HADPNIKDHREEAPLHVAVRTGNVEVVEALLN 249 6999***************************5 PP == domain 3 score: 12.5 bits; conditional E-value: 9.4e-05 Ank_5 1 LlengpadlnrldgegytpLhvAak...ygaleivrlLl 36 Ll+++ ++n++ +++ytpLh+Aa+ ++a ei ++Ll FUN_000351-T1 247 LLNHTATNVNIEGRNRYTPLHNAAHlehRNAVEICQKLL 285 7888899*****************632366666666666 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0011 Ank_5 2 lengpadlnrldgegytpLhvAakygaleivrlLl 36 l+++ a++ ++ + +tpL vAa +g++ei+ l++ FUN_000351-T1 285 LDCR-ANVTARGVDHMTPLSVAAQKGSAEIMALFF 318 6666.66666666779***************9998 PP == domain 5 score: 3.1 bits; conditional E-value: 0.084 Ank_5 14 gegytpLhvAakygaleivrlLlangvdlnl 44 g+ Lh+A+ g l v+l+l++g+++++ FUN_000351-T1 342 GG--SLLHLAVDSGVLKAVKLCLEYGCSVTA 370 33..88*********************9876 PP == domain 6 score: 12.4 bits; conditional E-value: 9.6e-05 Ank_5 11 rldgegytpLhvAakygaleivrlLlangvdlnl 44 r+dg+ tp+h+A++ galei++ L++++ +++ FUN_000351-T1 373 RRDGG--TPIHLACRLGALEILKCLYEHDPAAFE 404 34444..******************998877765 PP == domain 7 score: 16.2 bits; conditional E-value: 6.2e-06 Ank_5 13 dgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 d+e +tpLh + ++ +v++L+++gvdln +d e +tpl FUN_000351-T1 409 DKEDMTPLHRCSMFNHVGVVQFLVDHGVDLNPRDRERCTPL 449 78899**********************************97 PP == domain 8 score: 29.1 bits; conditional E-value: 5.7e-10 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 L+++g ++++ +++++ tpL +Aa +g++ +v lLl+ng+d+++ de t+l+ FUN_000351-T1 431 LVDHGvDLNPRDRERC--TPLLLAAAHGCSAVVSLLLENGADVTCEDEKRRTALH 483 89***99999999999..**********************************997 PP == domain 9 score: 26.8 bits; conditional E-value: 3e-09 Ank_5 9 lnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 +n +d g t+Lh+Aa +g l v+lLl+ng+d+ lk+ +tpl+lA FUN_000351-T1 507 VNQRDSTGSTALHYAAQGGFLKSVLLLLKNGADPSLKNTKLETPLHLA 554 678888889*************************************99 PP == domain 10 score: 21.7 bits; conditional E-value: 1.2e-07 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLla 37 Ll+ng ad+ ++++ +tpLh+Aa+yg l+iv++L++ FUN_000351-T1 533 LLKNG-ADPSLKNTKLETPLHLAASYGWLPIVKKLME 568 899**.99999************************94 PP == domain 11 score: 20.2 bits; conditional E-value: 3.4e-07 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + tpLh+Aa +g ++v++Ll +++ +d +g tpl++A FUN_000351-T1 578 GNLSDLTPLHLAACNGQDRVVKFLL-DRGATIERDTDGRTPLHFA 621 455666*******************.88888899999*****998 PP == domain 12 score: 11.5 bits; conditional E-value: 0.00019 Ank_5 13 dgegytpLhvAakygaleivrlLl 36 d++g tpLh+Aa +g+l v+l++ FUN_000351-T1 611 DTDGRTPLHFAAAKGSLKSVQLIC 634 45566************9999987 PP == domain 13 score: 25.0 bits; conditional E-value: 1.1e-08 Ank_5 8 dlnrldgegy.tpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 ++n +d++ + t+Lh+Aak+g++++v ++l + + + +++ +++++ld+A FUN_000351-T1 640 SINVEDNKDQdTALHLAAKNGHPDVVTYFLSHESQNVTYNGYNQNALDVA 689 55555555555*************************************98 PP == domain 14 score: -3.5 bits; conditional E-value: 9.6 Ank_5 19 pLhvAakygalei 31 Lh+++ky++ ++ FUN_000351-T1 778 SLHTMVKYKRVNC 790 69*****998876 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.1 1.4e-07 0.00034 14 118 .. 157 261 .. 153 286 .. 0.81 2 ? 2.9 0.0 0.049 1.1e+02 50 107 .. 266 320 .. 258 339 .. 0.73 3 ? 4.7 0.0 0.013 31 48 113 .. 378 441 .. 323 446 .. 0.71 4 ! 6.1 0.0 0.0052 12 49 107 .. 415 467 .. 406 485 .. 0.72 5 ! 11.2 0.0 0.00014 0.32 6 106 .. 476 568 .. 471 573 .. 0.73 6 ! 7.8 0.0 0.0015 3.6 36 104 .. 573 633 .. 568 636 .. 0.73 7 ! 12.1 0.0 7.4e-05 0.17 20 68 .. 616 671 .. 611 685 .. 0.82 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1.4e-07 Ank_KRIT1 14 yvklddeeLrkaaakGdeetvariL.nvrekvddpes.....lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikl 103 y ++++++L++++ kG+ + + +L + +e++d+ +s l+ +G+ + +++Ll +adp+ +k+ ++Pl a+ +n++v++ FUN_000351-T1 157 YGDNEKDTLHTLSRKGNIQEISALLsQQNEEIDKRDSygktaLHCSVSAGQVDTVKYLLY-NHADPN---IKDH--REEAPLHVAVRTGNVEVVEA 246 6678899****************994456789999999999999*************996.577887...6654..5679**************** PP Ank_KRIT1 104 lldqeefdptrrlkg 118 ll+++ + +++ ++ FUN_000351-T1 247 LLNHTATNVNIEGRN 261 ****99988877333 PP == domain 2 score: 2.9 bits; conditional E-value: 0.049 Ank_KRIT1 50 lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 l++Aa+ h++++++ +l ++ ++ v+ ++ tPl a ++ ++++ l+ ++ FUN_000351-T1 266 LHNAAHLEHRNAVEICQKLLDCRAN---VTARGVDHMTPLSVAAQKGSAEIMALFFKK 320 6777777788888887777777777...677777888888777777888888887665 PP == domain 3 score: 4.7 bits; conditional E-value: 0.013 Ank_KRIT1 48 eslvaAakgGheevlqlLlalGkadpdPepvksl..kpeystPllAaiGrenlkvikllldqe.efdpt 113 ++ A++ G e+l+ L++ dP++ + + ++e tPl +++ v+++l+d+ +++p+ FUN_000351-T1 378 TPIHLACRLGALEILKCLYE-----HDPAAFERTlvDKEDMTPLHRCSMFNHVGVVQFLVDHGvDLNPR 441 34999**********99986.....4677776665788999***9999899*********985246665 PP == domain 4 score: 6.1 bits; conditional E-value: 0.0052 Ank_KRIT1 49 slvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 l+ + h v+q+L++ G +d +P + e tPll a ++ +v++lll++ FUN_000351-T1 415 PLHRCSMFNHVGVVQFLVDHG-VDLNP-----RDRERCTPLLLAAAHGCSAVVSLLLEN 467 566666667778888888877.34443.....367889***9888999********986 PP == domain 5 score: 11.2 bits; conditional E-value: 0.00014 Ank_KRIT1 6 ektsndllyvklddeeLrkaaakGdeetvariLnvrekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPl.lAaiGrenlkv 100 ek + l + +d++++++ + +++ ++ ++n r+++ + +l++Aa+gG + + lLl+ G adp +k +++++tPl lAa + l + FUN_000351-T1 476 EKRRTALHWAVGQDKTIERLLKDVQVQELK-LVNQRDST-GSTALHYAAQGGFLKSVLLLLKNG-ADPS---LK--NTKLETPLhLAAS-YGWLPI 562 667777888888888888887777766654.55666666.7889***********999999988.4555...44..468999*977665.477777 PP Ank_KRIT1 101 ikllld 106 +k l++ FUN_000351-T1 563 VKKLME 568 777665 PP == domain 6 score: 7.8 bits; conditional E-value: 0.0015 Ank_KRIT1 36 riLnvrekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikll 104 r++nv + d l+ Aa G+++v+++Ll+ G + +++ tPl a ++ lk ++l+ FUN_000351-T1 573 RMMNVGNLS-DLTPLHLAACNGQDRVVKFLLDRGATIE-------RDTDGRTPLHFAAAKGSLKSVQLI 633 677777666.9999*****************9997522.......245667777555556677777765 PP == domain 7 score: 12.1 bits; conditional E-value: 7.4e-05 Ank_KRIT1 20 eeLrkaaakGdeetvari.......LnvrekvddpeslvaAakgGheevlqlLlal 68 + L+ aaakG + v+ i +nv+++ d+ +l+ Aak Gh +v+ ++l FUN_000351-T1 616 TPLHFAAAKGSLKSVQLIcsscpnsINVEDNKDQDTALHLAAKNGHPDVVTYFLSH 671 56888899999988887644444447999999999***************999875 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.3 22.1 5.2e-17 1.2e-13 5 238 .. 817 1046 .. 812 1051 .. 0.83 Alignments for each domain: == domain 1 score: 51.3 bits; conditional E-value: 5.2e-17 Ion_trans 5 elfilllillntvvlaletyfqpeekel.klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil..seskeslsll 95 ++il+l++l+++++ le ++ ++ l ++ ++ +v+ + +l +++i+ ++ kYl + n++ ++ ++ sl+ ++ + + +++ FUN_000351-T1 817 GFYILFLVMLTAMTVLLEKDTENTQSPLlDVPRFTIVVMSLFHLLKEIFQIWDEKF--KYLLKIDNWMEWFLYMTSLAYMFQyhQ---SPDNSV 905 58899************98888855555888889999999****************..********************8875432...233334 PP Ion_trans 96 rvlrll.rllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwlfqtlt 188 ++ ++ ++ ++ ++rr+ ++ +++ ++++++++l+++++l++ ++++f+i ++ l+ ++ + ++ r+ Fd ++++l+++f ++ FUN_000351-T1 906 AAAAIFiAWVIFVLYLRRFSSFGIYIIMMTNIIRTLVKIIILFIPFVIAFGIPFFLLLPKRTE----PGGSTASTRYLFDHLPYSLFTTFMLIL 995 3333333778888999**************************************999933333....33444455566**************** PP Ion_trans 189 te.gwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqel 238 +e ++ ++ + +++i+++++++f++++ +++ nlli++ + ++++ FUN_000351-T1 996 GEmKYPHTVFKYQPLPHPSISYVVYIIFCLCMPIIIKNLLIGLSVGDVNRI 1046 **77777777777777**************************988877766 PP >> Nucleopor_Nup85 Nup85 Nucleoporin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 2.5e-05 0.058 391 454 .. 640 703 .. 629 725 .. 0.94 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2.5e-05 Nucleopor_Nup85 391 rlplktnddaekllsiCaklkLpevaksIckilgkrllkegrlgeAlawaskagdaelvkriaw 454 +++++n+d + +l+++ak++ p+v++ +++ ++++ ++g +Al a+ ag+ ++v ia+ FUN_000351-T1 640 SINVEDNKDQDTALHLAAKNGHPDVVTYFLSHESQNVTYNGYNQNALDVAIEAGKEQVVLAIAE 703 68899****************************************************9988885 PP >> TSKS Testis-specific serine kinase substrate # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 3.2e-05 0.074 119 166 .. 1106 1153 .. 1084 1159 .. 0.86 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 3.2e-05 TSKS 119 seaelqkviagleelrrevssltarwqqeegavkealrllgglGgrld 166 s ++ v + l ++ ++s+lt + +q+e ++++rllg l rl FUN_000351-T1 1106 SATQQTYVNPALVQINEKISKLTNKVEQQEDKFQNIIRLLGRLDQRLT 1153 3344456999************************************96 PP >> IFT57 Intra-flagellar transport protein 57 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 2.0 0.00012 0.28 189 312 .. 1052 1180 .. 1044 1197 .. 0.78 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00012 IFT57 189 ieskvdaaeWklEleRVlpqLkv.........tikadakDWrahleqmkkhkksieeslkevksqlkklqedisktlekiesrEkylnsqleel 273 +e++ + e lEleR +p+ ++ ++++ Wr++l + + k+ +++ + v+++l ++ e isk ++k+e++E ++++ FUN_000351-T1 1052 MEQHAMQVELLLELERATPRNVLrriwapscvEYPNRKRTWRQKLVEFGSPKRHSATQQTYVNPALVQINEKISKLTNKVEQQED----KFQNI 1141 566666778889****9988555668889987889999*********************************************97....56667 PP IFT57 274 iqeyreaqeelsevqekykelsegvsertrelaeiseel 312 i+ + ++ ++l+e++ + k+l+ +v ++ +e+ l FUN_000351-T1 1142 IRLLGRLDQRLTEMNPSGKTLTCTVDGQQVSTREVPPTL 1180 777777777777777777777777776666666665555 PP >> TilS TilS substrate binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.13 3.1e+02 9 55 .. 473 518 .. 471 522 .. 0.85 2 ? -2.5 0.0 3.9 9.1e+03 45 67 .. 691 711 .. 684 712 .. 0.69 3 ? 6.6 0.2 0.0058 14 3 34 .. 1059 1090 .. 1057 1100 .. 0.88 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.13 TilS 9 lsparrrrlLRrwLaqlg..lpmpsaahleeilrqlllaredaqpqlql 55 + +++rr +L+++ q +++ ++++e ++l+ +++d++++ +l FUN_000351-T1 473 CEDEKRRTALHWAVGQDKtiERLLKDVQVQE--LKLV-NQRDSTGSTAL 518 56789***********999999*********..7888.78888777665 PP == domain 2 score: -2.5 bits; conditional E-value: 3.9 TilS 45 aredaqpqlqlpgggvrRyrgrL 67 +++ q l+++ + rR+r+ + FUN_000351-T1 691 EAGKEQVVLAIA--EHRRWREMC 711 556666666777..99**99866 PP == domain 3 score: 6.6 bits; conditional E-value: 0.0058 TilS 3 laaLralsparrrrlLRrwLaqlglpmpsaah 34 ++ L++l a r++LRr++a ++ p +++ FUN_000351-T1 1059 VELLLELERATPRNVLRRIWAPSCVEYPNRKR 1090 7889*****************99998888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1199 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1443 (0.0564885); expected 510.9 (0.02) Passed bias filter: 837 (0.0327657); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.54u 0.41s 00:00:00.95 Elapsed: 00:00:00.43 # Mc/sec: 11138.48 // Query: FUN_000351-T2 [L=1144] Description: FUN_000351 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-118 388.3 29.7 2.2e-16 60.7 0.0 8.8 11 Ank_2 Ankyrin repeats (3 copies) 8.9e-85 274.2 23.4 1.2e-07 32.1 0.1 15.7 16 Ank Ankyrin repeat 1.7e-65 208.9 9.4 0.0031 18.3 0.0 16.5 16 Ank_3 Ankyrin repeat 7.2e-60 198.1 11.5 3.9e-07 30.7 0.0 12.6 14 Ank_4 Ankyrin repeats (many copies) 1.3e-51 172.4 20.2 1.2e-06 29.2 0.2 13.7 14 Ank_5 Ankyrin repeats (many copies) 1.4e-18 67.5 3.2 0.00034 20.8 0.1 7.3 7 Ank_KRIT1 KRIT1 ankyrin-repeats domain 7.8e-14 51.9 22.1 1.1e-13 51.4 22.1 1.2 1 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.03 13.5 0.0 0.055 12.6 0.0 1.3 1 Nucleopor_Nup85 Nup85 Nucleoporin 1 10.2 2.9 13 6.6 0.2 3.1 3 TilS TilS substrate binding domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.6 0.1 3.5e-14 9.9e-11 27 90 .] 155 225 .. 128 225 .. 0.78 2 ! 41.1 1.9 1e-13 2.8e-10 19 88 .. 218 293 .. 217 294 .. 0.86 3 ! 30.5 0.1 2e-10 5.6e-07 8 88 .. 276 370 .. 273 372 .. 0.78 4 ! 37.0 0.0 1.9e-12 5.4e-09 1 83 [. 302 399 .. 302 406 .. 0.80 5 ! 58.4 0.0 4e-19 1.1e-15 1 90 [] 346 442 .. 346 442 .. 0.89 6 ! 48.4 0.0 5.3e-16 1.5e-12 24 90 .] 407 475 .. 401 475 .. 0.93 7 ! 59.8 0.2 1.5e-19 4.2e-16 1 90 [] 449 544 .. 449 544 .. 0.87 8 ! 51.4 0.0 6.3e-17 1.8e-13 14 87 .. 531 609 .. 530 612 .. 0.85 9 ! 60.7 0.0 7.9e-20 2.2e-16 1 88 [. 551 643 .. 551 645 .. 0.86 10 ! 50.8 0.7 9.6e-17 2.7e-13 1 82 [. 618 704 .. 618 706 .. 0.90 11 ? -3.4 0.0 7.8 2.2e+04 31 51 .. 1045 1065 .. 1030 1071 .. 0.60 Alignments for each domain: == domain 1 score: 42.6 bits; conditional E-value: 3.5e-14 Ank_2 27 k....ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 n++ Lh ++g+++ +++Ll++ +++ d++g+taLh++++ g++++vk+Ll + ad+n+kd FUN_000351-T2 155 GeygdNEKDTLHTLSRKGNIQEISALLSQQnEEIDkrDSYGKTALHCSVSAGQVDTVKYLLYNHADPNIKD 225 1444578999**********99*999995323345569***********************999****998 PP == domain 2 score: 41.1 bits; conditional E-value: 1e-13 Ank_2 19 gadanlqdkngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaes...ghleivklLlekgadina 88 +ad+n++d ++e +Lh+A+++g++e+v++Ll+h +vn +n +t+Lh Aa + +ei++ Ll++ a+++a FUN_000351-T2 218 HADPNIKDHREEAPLHVAVRTGNVEVVEALLNHTaTNVNieGRNRYTPLHNAAHLehrNAVEICQKLLDCRANVTA 293 799*****************************976567776799*********88666668999999988888875 PP == domain 3 score: 30.5 bits; conditional E-value: 2e-10 Ank_2 8 gnlelvklLlegadanlqdk..ngetaLhlAaknghleivklLlehgad...............vndnngrtaLhyAaesghleivklLlekgadi 86 + e+++ Ll ++ an++ + +t+L +Aa++g++ei+ l+ ++ + v d +g + Lh+A+ sg l++vkl le+g+++ FUN_000351-T2 276 NAVEICQKLL-DCRANVTARgvDHMTPLSVAAQKGSAEIMALFFKKC-SetqrgaklqqehlygV-DFEGGSLLHLAVDSGVLKAVKLCLEYGCSV 368 5569******.666665555679*****************9999952.23445555654444333.588******************999***998 PP Ank_2 87 na 88 +a FUN_000351-T2 369 TA 370 75 PP == domain 4 score: 37.0 bits; conditional E-value: 1.9e-12 Ank_2 1 LmlAakngnlelvklLl.eg....adanlqdk.........ngetaLhlAaknghleivklLlehgadvn...dnngrtaLhyAaesghleivklL 79 L +Aa++g+ e++ l++ + a+l + +g + LhlA+ +g l++vkl le+g++v ++g t++h+A++ g lei+k L FUN_000351-T2 302 LSVAAQKGSAEIMALFFkKCsetqRGAKL--QqehlygvdfEGGSLLHLAVDSGVLKAVKLCLEYGCSVTavkRRDGGTPIHLACRLGALEILKCL 395 6789999*999999999622233312233..13477888899***********************98855565699******************** PP Ank_2 80 lekg 83 e++ FUN_000351-T2 396 YEHD 399 9863 PP == domain 5 score: 58.4 bits; conditional E-value: 4e-19 Ank_2 1 LmlAakngnlelvklLl.egadanlqdk.ngetaLhlAaknghleivklLlehg.advn....dnngrtaLhyAaesghleivklLlekgadinak 89 L+lA+ +g l++vkl l +g+++ ++ +g t++hlA++ g lei+k+L eh+ a+ + d++ +t+Lh +++ +h+ +v++L+++g+d+n + FUN_000351-T2 346 LHLAVDSGVLKAVKLCLeYGCSVTAVKRrDGGTPIHLACRLGALEILKCLYEHDpAAFErtlvDKEDMTPLHRCSMFNHVGVVQFLVDHGVDLNPR 441 8*******99*******999999944445************************76443345667*****************************988 PP Ank_2 90 d 90 d FUN_000351-T2 442 D 442 7 PP == domain 6 score: 48.4 bits; conditional E-value: 5.3e-16 Ank_2 24 lqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+dk+ +t+Lh + + +h+ +v++L++hg+d+n d++ +t+L +Aa +g+ +v lLle+gad++ +d FUN_000351-T2 407 LVDKEDMTPLHRCSMFNHVGVVQFLVDHGVDLNprDRERCTPLLLAAAHGCSAVVSLLLENGADVTCED 475 567788*************************99999*****************************9876 PP == domain 7 score: 59.8 bits; conditional E-value: 1.5e-19 Ank_2 1 LmlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLle....hgad...vn..dnngrtaLhyAaesghleivklLlekgadi 86 L lAa++g + +v lLl +gad+ ++d++ +taLh+A+ ++ ++++ Ll+ + + vn d++g taLhyAa+ g l+ v lLl++gad+ FUN_000351-T2 449 LLLAAAHGCSAVVSLLLeNGADVTCEDEKRRTALHWAVGQD--KTIERLLKdvqvQ--ElklVNqrDSTGSTALHYAAQGGFLKSVLLLLKNGADP 540 679*****999999999***********************9..8898888755442..144455669****************************9 PP Ank_2 87 nakd 90 +k+ FUN_000351-T2 541 SLKN 544 9875 PP == domain 8 score: 51.4 bits; conditional E-value: 6.3e-17 Ank_2 14 klLl.egadanlqdkngetaLhlAaknghleivklLle..hg..advn..dnngrtaLhyAaesghleivklLlekgadin 87 lLl +gad+ l++++ et+LhlAa++g+l ivk L+e + + n + + t+Lh+Aa++g+ +vk+Ll++ga i+ FUN_000351-T2 531 LLLLkNGADPSLKNTKLETPLHLAASYGWLPIVKKLMEgrQTrmM--NvgNLSDLTPLHLAACNGQDRVVKFLLDRGATIE 609 46779******999999********************95422333..4557999*********************999886 PP == domain 9 score: 60.7 bits; conditional E-value: 7.9e-20 Ank_2 1 LmlAakngnlelvklLlegadanlqdk...ngetaLhlAaknghleivklLlehgadvn.dnngrtaLhyAaesghleivklLlek.gadina 88 L+lAa++g l +vk L+eg ++++++ t+LhlAa+ng+ +vk+Ll+ ga ++ d +grt+Lh+Aa +g+l+ v+l++++ +in+ FUN_000351-T2 551 LHLAASYGWLPIVKKLMEGRQTRMMNVgnlSDLTPLHLAACNGQDRVVKFLLDRGATIErDTDGRTPLHFAAAKGSLKSVQLICSScPNSINV 643 8*******99*******887766666566788*********************99878889*********************99543446665 PP == domain 10 score: 50.8 bits; conditional E-value: 9.6e-17 Ank_2 1 LmlAakngnlelvklLl..egadanlqdk.ngetaLhlAaknghleivklLlehg.advn.dnngrtaLhyAaesghleivklLlek 82 L++Aa++g+l+ v+l+ +++++n++d+ + +taLhlAakngh ++v ++l+h+ +v + ++++aL +A+e g +++v ++e+ FUN_000351-T2 618 LHFAAAKGSLKSVQLICssCPNSINVEDNkDQDTALHLAAKNGHPDVVTYFLSHEsQNVTyNGYNQNALDVAIEAGKEQVVLAIAEH 704 8***************9999999998888899*********************975445577999***************9988765 PP == domain 11 score: -3.4 bits; conditional E-value: 7.8 Ank_2 31 taLhlAaknghlei.vklLleh 51 +L+ A + +h+ + v+lLle FUN_000351-T2 1045 RILQSAKMEQHA-MqVELLLEL 1065 567777777664.448888874 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2 5.5e+03 6 32 .. 165 192 .. 165 193 .. 0.78 2 ! 32.1 0.1 4.3e-11 1.2e-07 1 32 [. 194 225 .. 194 226 .. 0.94 3 ! 23.3 0.1 2.6e-08 7.4e-05 5 31 .. 231 258 .. 228 260 .. 0.87 4 ! 18.7 0.4 7.8e-07 0.0022 2 31 .. 262 294 .. 261 296 .. 0.82 5 ! 6.3 0.0 0.0071 20 2 20 .. 298 316 .. 297 323 .. 0.86 6 ! 11.1 0.0 0.0002 0.57 3 31 .. 343 371 .. 341 373 .. 0.88 7 ! 15.0 0.1 1.2e-05 0.034 1 24 [. 375 398 .. 375 404 .. 0.87 8 ! 24.3 0.0 1.2e-08 3.5e-05 3 32 .. 413 442 .. 411 443 .. 0.93 9 ! 23.0 0.1 3.4e-08 9.8e-05 3 32 .. 446 475 .. 444 476 .. 0.92 10 ! 8.8 0.0 0.0012 3.3 3 23 .. 479 497 .. 477 504 .. 0.81 11 ! 26.1 0.0 3.3e-09 9.4e-06 2 32 .. 514 544 .. 513 545 .. 0.94 12 ! 16.1 0.0 5.2e-06 0.015 3 25 .. 548 569 .. 546 576 .. 0.90 13 ! 26.1 0.0 3.5e-09 9.8e-06 3 28 .. 583 608 .. 581 612 .. 0.89 14 ! 20.3 0.0 2.4e-07 0.00068 1 31 [. 613 644 .. 613 646 .. 0.76 15 ! 22.5 0.0 4.7e-08 0.00013 2 24 .. 649 671 .. 648 679 .. 0.82 16 ? -2.2 0.0 3.6 1e+04 3 18 .. 683 698 .. 681 701 .. 0.85 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2 Ank 6 LHlAaraghlevvklLL.khGAdvnard 32 LH +r+g+++ + LL +++ ++ rd FUN_000351-T2 165 LHTLSRKGNIQEISALLsQQNEEIDKRD 192 7866889999999999966678888887 PP == domain 2 score: 32.1 bits; conditional E-value: 4.3e-11 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G T+LH+ ++ag++++vk+LL+++Ad+n++d FUN_000351-T2 194 YGKTALHCSVSAGQVDTVKYLLYNHADPNIKD 225 69********************779******9 PP == domain 3 score: 23.3 bits; conditional E-value: 2.6e-08 Ank 5 PLHlAaraghlevvklLLkh.GAdvnar 31 PLH+A+r g++evv+ LL+h +vn+ FUN_000351-T2 231 PLHVAVRTGNVEVVEALLNHtATNVNIE 258 9*****************7734799985 PP == domain 4 score: 18.7 bits; conditional E-value: 7.8e-07 Ank 2 GnTPLHlAaragh...levvklLLkhGAdvnar 31 +TPLH Aa+ h +e+++ LL+ A+v ar FUN_000351-T2 262 RYTPLHNAAHLEHrnaVEICQKLLDCRANVTAR 294 58*******5555556********778***997 PP == domain 5 score: 6.3 bits; conditional E-value: 0.0071 Ank 2 GnTPLHlAaraghlevvkl 20 +TPL +Aa++g+ e++ l FUN_000351-T2 298 HMTPLSVAAQKGSAEIMAL 316 68***********999876 PP == domain 6 score: 11.1 bits; conditional E-value: 0.0002 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnar 31 + LHlA+ g l+ vkl L++G++v a+ FUN_000351-T2 343 GSLLHLAVDSGVLKAVKLCLEYGCSVTAV 371 578*****99**********88***9886 PP == domain 7 score: 15.0 bits; conditional E-value: 1.2e-05 Ank 1 dGnTPLHlAaraghlevvklLLkh 24 dG TP+HlA+r g le++k L +h FUN_000351-T2 375 DGGTPIHLACRLGALEILKCLYEH 398 688*****************9854 PP == domain 8 score: 24.3 bits; conditional E-value: 1.2e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH +++ +h+ vv++L++hG+d+n rd FUN_000351-T2 413 MTPLHRCSMFNHVGVVQFLVDHGVDLNPRD 442 8*****999***********99*****998 PP == domain 9 score: 23.0 bits; conditional E-value: 3.4e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPL lAa +g+ vv lLL++GAdv + d FUN_000351-T2 446 CTPLLLAAAHGCSAVVSLLLENGADVTCED 475 8*******99**********98****9877 PP == domain 10 score: 8.8 bits; conditional E-value: 0.0012 Ank 3 nTPLHlAaraghlevvklLLk 23 +T+LH+A+ g+ ++++ LLk FUN_000351-T2 479 RTALHWAV--GQDKTIERLLK 497 8*****99..66679999994 PP == domain 11 score: 26.1 bits; conditional E-value: 3.3e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G T+LH+Aa+ g l+ v lLLk+GAd+ +++ FUN_000351-T2 514 GSTALHYAAQGGFLKSVLLLLKNGADPSLKN 544 99*******************98****9998 PP == domain 12 score: 16.1 bits; conditional E-value: 5.2e-06 Ank 3 nTPLHlAaraghlevvklLLkhG 25 TPLHlAa++g l +vk L + G FUN_000351-T2 548 ETPLHLAASYGWLPIVKKLME-G 569 6****************9983.5 PP == domain 13 score: 26.1 bits; conditional E-value: 3.5e-09 Ank 3 nTPLHlAaraghlevvklLLkhGAdv 28 TPLHlAa++g+ vvk+LL++GA + FUN_000351-T2 583 LTPLHLAACNGQDRVVKFLLDRGATI 608 6*******************889976 PP == domain 14 score: 20.3 bits; conditional E-value: 2.4e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhG.Advnar 31 dG+TPLH Aa +g+l+ v+l++++ ++n+ FUN_000351-T2 613 DGRTPLHFAAAKGSLKSVQLICSSCpNSINVE 644 8******99999*******9994332235655 PP == domain 15 score: 22.5 bits; conditional E-value: 4.7e-08 Ank 2 GnTPLHlAaraghlevvklLLkh 24 +T+LHlAa++gh++vv + L+h FUN_000351-T2 649 QDTALHLAAKNGHPDVVTYFLSH 671 68*******************65 PP == domain 16 score: -2.2 bits; conditional E-value: 3.6 Ank 3 nTPLHlAaraghlevv 18 + +L +A++ag ++vv FUN_000351-T2 683 QNALDVAIEAGKEQVV 698 7899****99999998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.54 1.5e+03 6 30 .. 165 189 .. 165 190 .. 0.88 2 ! 12.2 0.0 0.00011 0.32 1 31 [] 194 223 .. 194 223 .. 0.94 3 ! 17.0 0.0 2.9e-06 0.0084 5 30 .. 231 256 .. 228 257 .. 0.89 4 ! 9.0 0.1 0.0012 3.4 2 29 .. 262 291 .. 261 293 .. 0.83 5 ! 6.4 0.0 0.0088 25 2 25 .. 298 321 .. 297 325 .. 0.87 6 ! 13.6 0.0 3.8e-05 0.11 2 29 .. 342 368 .. 341 370 .. 0.92 7 ! 16.7 0.0 3.8e-06 0.011 1 27 [. 375 401 .. 375 404 .. 0.88 8 ! 18.3 0.0 1.1e-06 0.0031 3 30 .. 413 439 .. 411 439 .. 0.95 9 ! 18.3 0.1 1.2e-06 0.0033 3 30 .. 446 472 .. 444 473 .. 0.93 10 ? 5.3 0.0 0.02 57 3 23 .. 479 497 .. 477 502 .. 0.84 11 ! 14.6 0.0 1.8e-05 0.051 2 30 .. 514 541 .. 513 542 .. 0.93 12 ! 14.9 0.0 1.5e-05 0.042 3 23 .. 548 568 .. 546 572 .. 0.91 13 ! 14.4 0.0 2.2e-05 0.061 4 29 .. 584 608 .. 582 610 .. 0.93 14 ! 14.7 0.0 1.6e-05 0.047 1 30 [. 613 642 .. 613 643 .. 0.93 15 ! 15.3 0.0 1.1e-05 0.031 3 24 .. 650 671 .. 648 677 .. 0.87 16 ? 1.4 0.0 0.38 1.1e+03 1 24 [. 681 704 .. 681 707 .. 0.88 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.54 Ank_3 6 LhlAarngrleivklLleklgadin 30 Lh+ r g+++ + +Ll +++ +i+ FUN_000351-T2 165 LHTLSRKGNIQEISALLSQQNEEID 189 89********88*****98888776 PP == domain 2 score: 12.2 bits; conditional E-value: 0.00011 Ank_3 1 dgntpLhlAarngrleivklLleklgadina 31 +g t+Lh+ ++ g+++ vk+Ll ++ad+n+ FUN_000351-T2 194 YGKTALHCSVSAGQVDTVKYLLY-NHADPNI 223 799*******************9.9999985 PP == domain 3 score: 17.0 bits; conditional E-value: 2.9e-06 Ank_3 5 pLhlAarngrleivklLleklgadin 30 pLh+A+r g++e+v++Ll++ ++n FUN_000351-T2 231 PLHVAVRTGNVEVVEALLNHTATNVN 256 9******************8777777 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0012 Ank_3 2 gntpLhlAarngrl...eivklLleklgadi 29 +tpLh Aa+ + ei++ Ll+ + a++ FUN_000351-T2 262 RYTPLHNAAHLEHRnavEICQKLLD-CRANV 291 69************77778888888.88876 PP == domain 5 score: 6.4 bits; conditional E-value: 0.0088 Ank_3 2 gntpLhlAarngrleivklLlekl 25 ++tpL +Aa g+ ei+ l+++k+ FUN_000351-T2 298 HMTPLSVAAQKGSAEIMALFFKKC 321 78*************999998855 PP == domain 6 score: 13.6 bits; conditional E-value: 3.8e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g ++LhlA+ +g l++vkl+le +g+++ FUN_000351-T2 342 GGSLLHLAVDSGVLKAVKLCLE-YGCSV 368 789*******************.**987 PP == domain 7 score: 16.7 bits; conditional E-value: 3.8e-06 Ank_3 1 dgntpLhlAarngrleivklLleklga 27 dg tp+hlA+r g lei+k+L e+ +a FUN_000351-T2 375 DGGTPIHLACRLGALEILKCLYEHDPA 401 689******************997665 PP == domain 8 score: 18.3 bits; conditional E-value: 1.1e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +tpLh + +++++ +v++L++ +g+d+n FUN_000351-T2 413 MTPLHRCSMFNHVGVVQFLVD-HGVDLN 439 7********************.****98 PP == domain 9 score: 18.3 bits; conditional E-value: 1.2e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +tpL lAa +g+ +v lLle +gad+ FUN_000351-T2 446 CTPLLLAAAHGCSAVVSLLLE-NGADVT 472 8********************.****85 PP == domain 10 score: 5.3 bits; conditional E-value: 0.02 Ank_3 3 ntpLhlAarngrleivklLle 23 +t+Lh+A+ ++ ++ Ll+ FUN_000351-T2 479 RTALHWAVGQDKT--IERLLK 497 8********9999..888877 PP == domain 11 score: 14.6 bits; conditional E-value: 1.8e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 g t+Lh+Aa g l+ v lLl+ +gad+ FUN_000351-T2 514 GSTALHYAAQGGFLKSVLLLLK-NGADPS 541 88************99******.****85 PP == domain 12 score: 14.9 bits; conditional E-value: 1.5e-05 Ank_3 3 ntpLhlAarngrleivklLle 23 +tpLhlAa++g l+ivk L e FUN_000351-T2 548 ETPLHLAASYGWLPIVKKLME 568 7****************9998 PP == domain 13 score: 14.4 bits; conditional E-value: 2.2e-05 Ank_3 4 tpLhlAarngrleivklLleklgadi 29 tpLhlAa ng+ +vk+Ll+ +ga i FUN_000351-T2 584 TPLHLAACNGQDRVVKFLLD-RGATI 608 9*******************.**988 PP == domain 14 score: 14.7 bits; conditional E-value: 1.6e-05 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 dg+tpLh+Aa g+l+ v+l++ ++ +in FUN_000351-T2 613 DGRTPLHFAAAKGSLKSVQLICSSCPNSIN 642 79*************99*****99999988 PP == domain 15 score: 15.3 bits; conditional E-value: 1.1e-05 Ank_3 3 ntpLhlAarngrleivklLlek 24 t+LhlAa+ng++++v ++l + FUN_000351-T2 650 DTALHLAAKNGHPDVVTYFLSH 671 69*****************984 PP == domain 16 score: 1.4 bits; conditional E-value: 0.38 Ank_3 1 dgntpLhlAarngrleivklLlek 24 +++++L +A++ g+ ++v ++ e+ FUN_000351-T2 681 YNQNALDVAIEAGKEQVVLAIAEH 704 6899************99999885 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.0 3e-10 8.6e-07 1 50 [] 165 215 .. 165 215 .. 0.94 2 ! 30.7 0.0 1.4e-10 3.9e-07 7 50 .] 205 248 .. 203 248 .. 0.96 3 ? 4.5 0.1 0.025 70 30 50 .] 262 285 .. 252 285 .. 0.66 4 ! 9.8 0.2 0.00053 1.5 1 48 [. 266 316 .. 266 318 .. 0.92 5 ! 25.2 0.0 7.5e-09 2.1e-05 1 49 [. 346 395 .. 346 396 .. 0.97 6 ! 18.4 0.0 1e-06 0.0028 26 50 .] 408 432 .. 398 432 .. 0.91 7 ! 28.4 0.1 7.2e-10 2.1e-06 1 41 [. 416 456 .. 416 461 .. 0.97 8 ! 18.0 0.1 1.3e-06 0.0037 3 39 .. 451 487 .. 449 496 .. 0.91 9 ! 14.0 0.0 2.5e-05 0.071 11 50 .] 490 534 .. 487 534 .. 0.75 10 ! 22.3 0.0 5.9e-08 0.00017 1 49 [. 518 566 .. 518 567 .. 0.95 11 ! 6.6 0.0 0.0052 15 27 50 .] 579 602 .. 576 602 .. 0.90 12 ! 24.1 0.0 1.6e-08 4.6e-05 1 48 [. 586 632 .. 586 633 .. 0.89 13 ! 18.3 0.0 1.1e-06 0.0031 27 50 .] 646 669 .. 638 669 .. 0.88 14 ? -0.1 0.0 0.67 1.9e+03 1 19 [. 686 704 .. 675 723 .. 0.67 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 3e-10 Ank_4 1 lhaAaksghlellklLlen.gadinatdgngetaLhfAasngnlevlklLl 50 lh + +g+++ + Ll+ +i+++d +g taLh+ +s g+++ +k+Ll FUN_000351-T2 165 LHTLSRKGNIQEISALLSQqNEEIDKRDSYGKTALHCSVSAGQVDTVKYLL 215 799999***********654999***************************8 PP == domain 2 score: 30.7 bits; conditional E-value: 1.4e-10 Ank_4 7 sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 +g+++++k+Ll n ad+n d+ e +Lh A++ gn+ev++ Ll FUN_000351-T2 205 AGQVDTVKYLLYNHADPNIKDHREEAPLHVAVRTGNVEVVEALL 248 799**************************************997 PP == domain 3 score: 4.5 bits; conditional E-value: 0.025 Ank_4 30 getaLhfAasngn...levlklLl 50 +t+Lh+Aa+ ++ +e+++ Ll FUN_000351-T2 262 RYTPLHNAAHLEHrnaVEICQKLL 285 369******655533477777775 PP == domain 4 score: 9.8 bits; conditional E-value: 0.00053 Ank_4 1 lhaAak...sghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 lh Aa+ ++ +e+++ Ll+ +a++ a+ + +t+L Aa++g+ e+ l FUN_000351-T2 266 LHNAAHlehRNAVEICQKLLDCRANVTARGVDHMTPLSVAAQKGSAEIMAL 316 799999999********************889************9998765 PP == domain 5 score: 25.2 bits; conditional E-value: 7.5e-09 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklL 49 lh A+ sg l+++kl+le+g ++ a+ ++g t++h A++ g le+lk+L FUN_000351-T2 346 LHLAVDSGVLKAVKLCLEYGCSVTAVkRRDGGTPIHLACRLGALEILKCL 395 799999******************************************98 PP == domain 6 score: 18.4 bits; conditional E-value: 1e-06 Ank_4 26 tdgngetaLhfAasngnlevlklLl 50 +d++++t+Lh++++++++ v+++L+ FUN_000351-T2 408 VDKEDMTPLHRCSMFNHVGVVQFLV 432 399********************96 PP == domain 7 score: 28.4 bits; conditional E-value: 7.2e-10 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasng 41 lh++ +++h+ ++++L+++g+d+n +d++ t+L Aa++g FUN_000351-T2 416 LHRCSMFNHVGVVQFLVDHGVDLNPRDRERCTPLLLAAAHG 456 8**************************************99 PP == domain 8 score: 18.0 bits; conditional E-value: 1.3e-06 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAas 39 Aa++g+ ++ lLlengad+ + d+ +taLh+A+ FUN_000351-T2 451 LAAAHGCSAVVSLLLENGADVTCEDEKRRTALHWAVG 487 6999****************9999***********95 PP == domain 9 score: 14.0 bits; conditional E-value: 2.5e-05 Ank_4 11 ellklLlengad......inatdgngetaLhfAasngnlevlklLl 50 +++++Ll+ ++ +n +d g taLh+Aa++g l+ + lLl FUN_000351-T2 490 KTIERLLKD-VQvqelklVNQRDSTGSTALHYAAQGGFLKSVLLLL 534 566777743.22336666888899**************99999886 PP == domain 10 score: 22.3 bits; conditional E-value: 5.9e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+Aa g l+ + lLl+ngad+ + et+Lh Aas g l ++k L FUN_000351-T2 518 LHYAAQGGFLKSVLLLLKNGADPSLKNTKLETPLHLAASYGWLPIVKKL 566 8***************************************988888876 PP == domain 11 score: 6.6 bits; conditional E-value: 0.0052 Ank_4 27 dgngetaLhfAasngnlevlklLl 50 + ++ t+Lh Aa ng+ +v+k+Ll FUN_000351-T2 579 NLSDLTPLHLAACNGQDRVVKFLL 602 56789*****************97 PP == domain 12 score: 24.1 bits; conditional E-value: 1.6e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 lh Aa g+ +++k+Ll+ ga ++d +g+t+LhfAa++g+l+ ++l FUN_000351-T2 586 LHLAACNGQDRVVKFLLDRGAT-IERDTDGRTPLHFAAAKGSLKSVQL 632 6788889************985.567999*************999986 PP == domain 13 score: 18.3 bits; conditional E-value: 1.1e-06 Ank_4 27 dgngetaLhfAasngnlevlklLl 50 +++++taLh Aa+ng+++v+ ++l FUN_000351-T2 646 NKDQDTALHLAAKNGHPDVVTYFL 669 899*******************97 PP == domain 14 score: -0.1 bits; conditional E-value: 0.67 Ank_4 1 lhaAaksghlellklLlen 19 l++A+++g+++++ + e+ FUN_000351-T2 686 LDVAIEAGKEQVVLAIAEH 704 5566667777777666666 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.1 9.9e-08 0.00028 4 56 .] 183 235 .. 180 235 .. 0.91 2 ! 16.3 0.2 4.9e-06 0.014 6 37 .. 218 249 .. 216 253 .. 0.91 3 ! 12.5 1.1 7.5e-05 0.21 1 36 [. 247 285 .. 247 296 .. 0.75 4 ! 9.0 0.0 0.00096 2.7 2 36 .. 285 318 .. 284 334 .. 0.81 5 ? 3.3 0.0 0.06 1.7e+02 14 44 .. 342 370 .. 330 375 .. 0.84 6 ! 12.5 0.0 7.5e-05 0.21 11 44 .. 373 404 .. 362 407 .. 0.79 7 ! 16.3 0.0 4.8e-06 0.014 13 53 .. 409 449 .. 406 449 .. 0.95 8 ! 29.2 0.2 4.4e-10 1.2e-06 1 54 [. 431 483 .. 431 485 .. 0.95 9 ! 26.9 0.0 2.4e-09 6.7e-06 9 56 .] 507 554 .. 502 554 .. 0.94 10 ! 21.8 0.0 9.2e-08 0.00026 1 37 [. 533 568 .. 533 576 .. 0.91 11 ! 20.3 0.0 2.7e-07 0.00075 12 56 .] 578 621 .. 572 621 .. 0.88 12 ! 11.6 0.0 0.00014 0.41 13 36 .. 611 634 .. 605 640 .. 0.84 13 ! 25.1 0.2 8.5e-09 2.4e-05 8 56 .] 640 689 .. 636 689 .. 0.87 14 ? -3.3 0.0 7 2e+04 19 31 .. 778 790 .. 775 791 .. 0.83 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 9.9e-08 Ank_5 4 ngpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 ++ ++ +d +g t+Lh +++g + v++Ll n++d+n+kd + + pl++A FUN_000351-T2 183 QQNEEIDKRDSYGKTALHCSVSAGQVDTVKYLLYNHADPNIKDHREEAPLHVA 235 456788999999**************************************998 PP == domain 2 score: 16.3 bits; conditional E-value: 4.9e-06 Ank_5 6 padlnrldgegytpLhvAakygaleivrlLla 37 +ad+n++d + + pLhvA+++g+ e+v+ Ll+ FUN_000351-T2 218 HADPNIKDHREEAPLHVAVRTGNVEVVEALLN 249 6999***************************5 PP == domain 3 score: 12.5 bits; conditional E-value: 7.5e-05 Ank_5 1 LlengpadlnrldgegytpLhvAak...ygaleivrlLl 36 Ll+++ ++n++ +++ytpLh+Aa+ ++a ei ++Ll FUN_000351-T2 247 LLNHTATNVNIEGRNRYTPLHNAAHlehRNAVEICQKLL 285 7888899*****************632356666666666 PP == domain 4 score: 9.0 bits; conditional E-value: 0.00096 Ank_5 2 lengpadlnrldgegytpLhvAakygaleivrlLl 36 l+++ a++ ++ + +tpL vAa +g++ei+ l++ FUN_000351-T2 285 LDCR-ANVTARGVDHMTPLSVAAQKGSAEIMALFF 318 6666.66666666779***************9998 PP == domain 5 score: 3.3 bits; conditional E-value: 0.06 Ank_5 14 gegytpLhvAakygaleivrlLlangvdlnl 44 g+ Lh+A+ g l v+l+l++g+++++ FUN_000351-T2 342 GG--SLLHLAVDSGVLKAVKLCLEYGCSVTA 370 33..88*********************9876 PP == domain 6 score: 12.5 bits; conditional E-value: 7.5e-05 Ank_5 11 rldgegytpLhvAakygaleivrlLlangvdlnl 44 r+dg+ tp+h+A++ galei++ L++++ +++ FUN_000351-T2 373 RRDGG--TPIHLACRLGALEILKCLYEHDPAAFE 404 34444..******************998877765 PP == domain 7 score: 16.3 bits; conditional E-value: 4.8e-06 Ank_5 13 dgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 d+e +tpLh + ++ +v++L+++gvdln +d e +tpl FUN_000351-T2 409 DKEDMTPLHRCSMFNHVGVVQFLVDHGVDLNPRDRERCTPL 449 78899**********************************97 PP == domain 8 score: 29.2 bits; conditional E-value: 4.4e-10 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 L+++g ++++ +++++ tpL +Aa +g++ +v lLl+ng+d+++ de t+l+ FUN_000351-T2 431 LVDHGvDLNPRDRERC--TPLLLAAAHGCSAVVSLLLENGADVTCEDEKRRTALH 483 89***99999999999..**********************************997 PP == domain 9 score: 26.9 bits; conditional E-value: 2.4e-09 Ank_5 9 lnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 +n +d g t+Lh+Aa +g l v+lLl+ng+d+ lk+ +tpl+lA FUN_000351-T2 507 VNQRDSTGSTALHYAAQGGFLKSVLLLLKNGADPSLKNTKLETPLHLA 554 678888889*************************************99 PP == domain 10 score: 21.8 bits; conditional E-value: 9.2e-08 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLla 37 Ll+ng ad+ ++++ +tpLh+Aa+yg l+iv++L++ FUN_000351-T2 533 LLKNG-ADPSLKNTKLETPLHLAASYGWLPIVKKLME 568 899**.99999************************94 PP == domain 11 score: 20.3 bits; conditional E-value: 2.7e-07 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + tpLh+Aa +g ++v++Ll +++ +d +g tpl++A FUN_000351-T2 578 GNLSDLTPLHLAACNGQDRVVKFLL-DRGATIERDTDGRTPLHFA 621 455666*******************.88888899999*****998 PP == domain 12 score: 11.6 bits; conditional E-value: 0.00014 Ank_5 13 dgegytpLhvAakygaleivrlLl 36 d++g tpLh+Aa +g+l v+l++ FUN_000351-T2 611 DTDGRTPLHFAAAKGSLKSVQLIC 634 45566************9999987 PP == domain 13 score: 25.1 bits; conditional E-value: 8.5e-09 Ank_5 8 dlnrldgegy.tpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 ++n +d++ + t+Lh+Aak+g++++v ++l + + + +++ +++++ld+A FUN_000351-T2 640 SINVEDNKDQdTALHLAAKNGHPDVVTYFLSHESQNVTYNGYNQNALDVA 689 55555555555*************************************98 PP == domain 14 score: -3.3 bits; conditional E-value: 7 Ank_5 19 pLhvAakygalei 31 Lh+++ky++ ++ FUN_000351-T2 778 SLHTMVKYKRVNC 790 69*****998876 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.1 1.2e-07 0.00034 14 118 .. 157 261 .. 153 285 .. 0.82 2 ? 3.2 0.0 0.032 91 49 107 .. 265 320 .. 255 340 .. 0.74 3 ? 4.7 0.0 0.011 32 48 112 .. 378 440 .. 323 445 .. 0.71 4 ! 5.3 0.0 0.0076 22 50 107 .. 416 467 .. 408 472 .. 0.72 5 ! 11.3 0.0 0.0001 0.29 6 106 .. 476 568 .. 471 574 .. 0.73 6 ! 7.9 0.0 0.0011 3.2 35 104 .. 572 633 .. 567 636 .. 0.73 7 ! 12.1 0.0 5.7e-05 0.16 20 68 .. 616 671 .. 611 684 .. 0.82 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 1.2e-07 Ank_KRIT1 14 yvklddeeLrkaaakGdeetvariL.nvrekvddpes.....lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikl 103 y ++++++L++++ kG+ + + +L + +e++d+ +s l+ +G+ + +++Ll +adp+ +k+ ++Pl a+ +n++v++ FUN_000351-T2 157 YGDNEKDTLHTLSRKGNIQEISALLsQQNEEIDKRDSygktaLHCSVSAGQVDTVKYLLY-NHADPN---IKDH--REEAPLHVAVRTGNVEVVEA 246 6678899****************994456789999999999999*************996.577887...6654..5679**************** PP Ank_KRIT1 104 lldqeefdptrrlkg 118 ll+++ + +++ ++ FUN_000351-T2 247 LLNHTATNVNIEGRN 261 ****99988777333 PP == domain 2 score: 3.2 bits; conditional E-value: 0.032 Ank_KRIT1 49 slvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 l++Aa+ h++++++ +l ++ ++ v+ ++ tPl a ++ ++++ l+ ++ FUN_000351-T2 265 PLHNAAHLEHRNAVEICQKLLDCRAN---VTARGVDHMTPLSVAAQKGSAEIMALFFKK 320 57788888888888888888888887...777778888888777777888888887765 PP == domain 3 score: 4.7 bits; conditional E-value: 0.011 Ank_KRIT1 48 eslvaAakgGheevlqlLlalGkadpdPepvksl..kpeystPllAaiGrenlkvikllldqe.efdp 112 ++ A++ G e+l+ L++ dP++ + + ++e tPl +++ v+++l+d+ +++p FUN_000351-T2 378 TPIHLACRLGALEILKCLYE-----HDPAAFERTlvDKEDMTPLHRCSMFNHVGVVQFLVDHGvDLNP 440 34999**********99986.....4677776665788999**99999899*********98524555 PP == domain 4 score: 5.3 bits; conditional E-value: 0.0076 Ank_KRIT1 50 lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 l+ + h v+q+L++ G +d +P + e tPll a ++ +v++lll++ FUN_000351-T2 416 LHRCSMFNHVGVVQFLVDHG-VDLNP-----RDRERCTPLLLAAAHGCSAVVSLLLEN 467 55556666777777777777.34443.....367888999888888999999999986 PP == domain 5 score: 11.3 bits; conditional E-value: 0.0001 Ank_KRIT1 6 ektsndllyvklddeeLrkaaakGdeetvariLnvrekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPl.lAaiGrenlkv 100 ek + l + +d++++++ + +++ ++ ++n r+++ + +l++Aa+gG + + lLl+ G adp +k +++++tPl lAa + l + FUN_000351-T2 476 EKRRTALHWAVGQDKTIERLLKDVQVQELK-LVNQRDST-GSTALHYAAQGGFLKSVLLLLKNG-ADPS---LK--NTKLETPLhLAAS-YGWLPI 562 667777888888888888887777766654.55666666.7889***********999999988.4555...44..46899**977665.477777 PP Ank_KRIT1 101 ikllld 106 +k l++ FUN_000351-T2 563 VKKLME 568 777765 PP == domain 6 score: 7.9 bits; conditional E-value: 0.0011 Ank_KRIT1 35 ariLnvrekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikll 104 +r++nv + d l+ Aa G+++v+++Ll+ G + +++ tPl a ++ lk ++l+ FUN_000351-T2 572 TRMMNVGNLS-DLTPLHLAACNGQDRVVKFLLDRGATIE-------RDTDGRTPLHFAAAKGSLKSVQLI 633 5677777666.9999*****************9997522.......245667777555556677777765 PP == domain 7 score: 12.1 bits; conditional E-value: 5.7e-05 Ank_KRIT1 20 eeLrkaaakGdeetvari.......LnvrekvddpeslvaAakgGheevlqlLlal 68 + L+ aaakG + v+ i +nv+++ d+ +l+ Aak Gh +v+ ++l FUN_000351-T2 616 TPLHFAAAKGSLKSVQLIcsscpnsINVEDNKDQDTALHLAAKNGHPDVVTYFLSH 671 56888899999988887644444447999999999***************999875 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.4 22.1 3.9e-17 1.1e-13 5 238 .. 817 1046 .. 812 1051 .. 0.83 Alignments for each domain: == domain 1 score: 51.4 bits; conditional E-value: 3.9e-17 Ion_trans 5 elfilllillntvvlaletyfqpeekel.klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil..seskeslsll 95 ++il+l++l+++++ le ++ ++ l ++ ++ +v+ + +l +++i+ ++ kYl + n++ ++ ++ sl+ ++ + + +++ FUN_000351-T2 817 GFYILFLVMLTAMTVLLEKDTENTQSPLlDVPRFTIVVMSLFHLLKEIFQIWDEKF--KYLLKIDNWMEWFLYMTSLAYMFQyhQ---SPDNSV 905 58899************98888855555888889999999****************..********************8875432...233334 PP Ion_trans 96 rvlrll.rllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwlfqtlt 188 ++ ++ ++ ++ ++rr+ ++ +++ ++++++++l+++++l++ ++++f+i ++ l+ ++ + ++ r+ Fd ++++l+++f ++ FUN_000351-T2 906 AAAAIFiAWVIFVLYLRRFSSFGIYIIMMTNIIRTLVKIIILFIPFVIAFGIPFFLLLPKRTE----PGGSTASTRYLFDHLPYSLFTTFMLIL 995 3333333778888999**************************************999933333....33444455566**************** PP Ion_trans 189 te.gwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqel 238 +e ++ ++ + +++i+++++++f++++ +++ nlli++ + ++++ FUN_000351-T2 996 GEmKYPHTVFKYQPLPHPSISYVVYIIFCLCMPIIIKNLLIGLSVGDVNRI 1046 **77777777777777**************************988877766 PP >> Nucleopor_Nup85 Nup85 Nucleoporin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 1.9e-05 0.055 391 454 .. 640 703 .. 629 725 .. 0.94 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.9e-05 Nucleopor_Nup85 391 rlplktnddaekllsiCaklkLpevaksIckilgkrllkegrlgeAlawaskagdaelvkriaw 454 +++++n+d + +l+++ak++ p+v++ +++ ++++ ++g +Al a+ ag+ ++v ia+ FUN_000351-T2 640 SINVEDNKDQDTALHLAAKNGHPDVVTYFLSHESQNVTYNGYNQNALDVAIEAGKEQVVLAIAE 703 68899****************************************************9988885 PP >> TilS TilS substrate binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.1 2.9e+02 9 55 .. 473 518 .. 471 522 .. 0.85 2 ? -2.4 0.0 3 8.6e+03 45 67 .. 691 711 .. 684 712 .. 0.69 3 ? 6.6 0.2 0.0045 13 3 34 .. 1059 1090 .. 1057 1100 .. 0.88 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.1 TilS 9 lsparrrrlLRrwLaqlg..lpmpsaahleeilrqlllaredaqpqlql 55 + +++rr +L+++ q +++ ++++e ++l+ +++d++++ +l FUN_000351-T2 473 CEDEKRRTALHWAVGQDKtiERLLKDVQVQE--LKLV-NQRDSTGSTAL 518 56789***********999999*********..7888.78888777665 PP == domain 2 score: -2.4 bits; conditional E-value: 3 TilS 45 aredaqpqlqlpgggvrRyrgrL 67 +++ q l+++ + rR+r+ + FUN_000351-T2 691 EAGKEQVVLAIA--EHRRWREMC 711 556666666777..99**99866 PP == domain 3 score: 6.6 bits; conditional E-value: 0.0045 TilS 3 laaLralsparrrrlLRrwLaqlglpmpsaah 34 ++ L++l a r++LRr++a ++ p +++ FUN_000351-T2 1059 VELLLELERATPRNVLRRIWAPSCVEYPNRKR 1090 7889*****************99998888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1143 (0.0447446); expected 510.9 (0.02) Passed bias filter: 630 (0.0246624); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.48u 0.38s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 10897.94 // Query: FUN_000352-T1 [L=876] Description: FUN_000352 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-71 236.7 21.2 1.5e-12 47.6 0.0 9.3 9 CSD 'Cold-shock' DNA-binding domain 1.2e-53 179.7 3.1 1.4e-10 41.7 0.0 9.0 8 CSDE1 Cold shock domain-containing protein E1 CSD 4.1e-08 33.6 5.4 3.4 8.3 0.0 5.9 5 S1-like S1-like 4.7e-05 23.4 1.1 0.00011 22.3 1.1 1.6 1 SUZ-C SUZ-C motif 0.00048 20.9 9.2 1.7 9.5 0.3 6.0 6 S1 S1 RNA binding domain 0.001 19.3 0.9 1.2e+02 3.1 0.0 6.4 6 Rho_RNA_bind Rho termination factor, RNA-binding domain ------ inclusion threshold ------ 0.011 16.1 8.5 3.8 8.0 0.2 4.9 5 MazE_antitoxin Antidote-toxin recognition MazE, bacterial a 0.026 14.9 10.3 28 5.2 0.0 6.6 7 DUF2196 Uncharacterized conserved protein (DUF2196) 0.07 13.8 0.1 4.8 7.9 0.0 3.0 2 Poly_export Polysaccharide biosynthesis/export protein 0.074 13.8 0.0 0.3 11.9 0.0 2.0 1 PHA_gran_rgn Putative polyhydroxyalkanoic acid system pro 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 Cyclophil_like2 Cyclophilin-like family 7.6 6.8 14.7 21 5.4 0.3 5.7 5 OB_RNB Ribonuclease B OB domain Domain annotation for each model (and alignments): >> CSD 'Cold-shock' DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.6 0.0 7.3e-16 1.5e-12 2 65 .. 53 115 .. 52 116 .. 0.95 2 ! 6.5 0.0 0.0051 11 39 63 .. 185 211 .. 170 214 .. 0.75 3 ! 43.9 0.3 1.1e-14 2.3e-11 2 65 .. 223 283 .. 222 284 .. 0.96 4 ? 4.0 0.0 0.029 63 22 63 .. 333 374 .. 330 377 .. 0.71 5 ! 40.9 0.2 9.1e-14 1.9e-10 3 54 .. 391 441 .. 389 453 .. 0.89 6 ! 5.8 0.0 0.0081 17 41 65 .. 520 546 .. 502 547 .. 0.83 7 ! 44.9 0.4 5e-15 1.1e-11 2 65 .. 556 616 .. 555 617 .. 0.97 8 ? 4.5 0.0 0.022 46 39 63 .. 695 721 .. 688 724 .. 0.80 9 ! 45.4 0.3 3.5e-15 7.5e-12 4 65 .. 731 791 .. 728 792 .. 0.88 Alignments for each domain: == domain 1 score: 47.6 bits; conditional E-value: 7.3e-16 CSD 2 tGtVkwfnakkgfGFItpedgdkdvFvHfsaiqgdgfrsLkegqkVeFevee..gkkgpqAanVtk 65 tG+++++ ++GFI++ ++d ++F+H+s+i++d ++L g++ eFev++ ++++p A+ V++ FUN_000352-T1 53 TGVIEKLLH--SYGFIQCCERDLRIFFHYSQINEDP-EDLHVGDELEFEVTSdqRTGKPIACRVVR 115 899999999..*************************.**************98999*******985 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0051 CSD 39 rsLkegqkVeFevee..gkkgpqAanV 63 L +g+kVeF+v+ +++ +A ++ FUN_000352-T1 185 TPLHKGDKVEFYVTTdkRTGVVRAREI 211 4699*********99555555566655 PP == domain 3 score: 43.9 bits; conditional E-value: 1.1e-14 CSD 2 tGtVkwfnakkgfGFItpedgdkdvFvHfsaiqgdgfrsLkegqkVeFeveegkkgpqAanVtk 65 +G+V +++ +fGFI+++d+ +++F+H+s++ g+ +L ++VeF ++ +++++ A+ ++k FUN_000352-T1 223 QGVVSSMKE--SFGFIERADKVSEIFFHYSEFCGEV-SELMLCDDVEFGIQVRNGKEVAVRIKK 283 799****99..************************9.**********************99876 PP == domain 4 score: 4.0 bits; conditional E-value: 0.029 CSD 22 gdkdvFvHfsaiqgdgfrsLkegqkVeFevee..gkkgpqAanV 63 +++++ + +++qgd sL +g+ VeF++ ++ ++A+n+ FUN_000352-T1 333 TEEEIVFSERDLQGDL--SLRTGDIVEFNIAVdcRDLLKRATNI 374 5566666667788888..***********976455555566665 PP == domain 5 score: 40.9 bits; conditional E-value: 9.1e-14 CSD 3 GtVkwfnakkgfGFItpedgdkdvFvHfsaiqgdgfrsLkegqkVeFevee..g 54 G+V +++ gfGFI + d+d++ F+Hfs++ ++g +++ g++VeF v+e + FUN_000352-T1 391 GVVASLKE--GFGFIRCCDRDARMFFHFSELLDSG-HQVQVGDEVEFAVSEdmS 441 99999999..*************************.*************99552 PP == domain 6 score: 5.8 bits; conditional E-value: 0.0081 CSD 41 LkegqkVeFevee..gkkgpqAanVtk 65 ++ g+kVeF+++ +++ ++A+nVt+ FUN_000352-T1 520 VQYGDKVEFNLSIsqRTGFKRAVNVTV 546 688******876544888899***986 PP == domain 7 score: 44.9 bits; conditional E-value: 5e-15 CSD 2 tGtVkwfnakkgfGFItpedgdkdvFvHfsaiqgdgfrsLkegqkVeFeveegkkgpqAanVtk 65 +G V ++++ +fGF +++++dk+vF+H+s++ gd +L g++ e++++ ++++ +A+ V+k FUN_000352-T1 556 KGFVATLKE--NFGFLETSEHDKEVFFHYSEFDGDP-GELVLGDEMEYTIKCKNGKVSAETVVK 616 799******..************************9.9************************87 PP == domain 8 score: 4.5 bits; conditional E-value: 0.022 CSD 39 rsLkegqkVeFevee..gkkgpqAanV 63 L+ g+kV F + ++++++A ++ FUN_000352-T1 695 TVLQLGEKVRFHIGVdqQTGKERAMKI 721 479********9865558999999887 PP == domain 9 score: 45.4 bits; conditional E-value: 3.5e-15 CSD 4 tVkwfnakkgfGFItpedgd.kdvFvHfsaiqgdgfrsLkegqkVeFevee..gkkgpqAanVtk 65 V+ ++ +fGFI++e+++ k++F+H+s+++g+ +L+ g++VeF v++ ++++++A++V++ FUN_000352-T1 731 RVESLKG--QFGFIAYENEEgKNLFFHMSEVEGEV--ELQPGDEVEFVVVQnqKTRKMSACSVRR 791 6777777..9*****9876526*************..*************988899******986 PP >> CSDE1 Cold shock domain-containing protein E1 CSD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.012 25 56 81 .. 88 113 .. 71 116 .. 0.85 2 ! 41.7 0.0 6.4e-14 1.4e-10 17 84 .] 147 214 .. 137 214 .. 0.85 3 ? 0.6 0.0 0.41 8.8e+02 21 82 .. 222 282 .. 217 284 .. 0.68 4 ! 36.0 0.0 3.9e-12 8.3e-09 1 83 [. 297 376 .. 297 377 .. 0.92 5 ? 3.7 0.0 0.044 93 55 71 .. 424 440 .. 399 454 .. 0.82 6 ! 28.2 0.0 1e-09 2.2e-06 1 83 [. 467 546 .. 467 547 .. 0.90 7 ! 27.6 0.0 1.6e-09 3.3e-06 2 81 .. 631 721 .. 630 723 .. 0.71 8 ! 25.1 0.1 9.7e-09 2.1e-05 31 82 .. 740 790 .. 731 792 .. 0.88 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.012 CSDE1 56 slqkGdkvkFsisdkkrdgqevAtni 81 l Gd+ +F++ ++r+g+ A + FUN_000352-T1 88 DLHVGDELEFEVTSDQRTGKPIACRV 113 5889***************9998765 PP == domain 2 score: 41.7 bits; conditional E-value: 6.4e-14 CSDE1 17 tksenkglpgeveegiviydekGevytlaftakdv.kgkvslqkGdkvkFsisdkkrdgqevAtnielL 84 ks+++g+++ + g v y+++Ge ++l+f +dv + + l kGdkv+F + ++kr+g ++A+ i+lL FUN_000352-T1 147 IKSPSNGVIDP-DMGRVSYERNGEFFYLSFSSNDVvNTGTPLHKGDKVEFYVTTDKRTGVVRAREITLL 214 56666666654.6789******************735667799************************98 PP == domain 3 score: 0.6 bits; conditional E-value: 0.41 CSDE1 21 nkglpgeveegiviydekGevytlaftakdvkgkvs.lqkGdkvkFsisdkkrdgqevAtnie 82 ++g+ ++e + ++ +v + f + g+vs l d v+F i++ r+g+evA i+ FUN_000352-T1 222 YQGVVSSMKESFGFIERADKVSEIFFHYSEFCGEVSeLMLCDDVEFGIQV--RNGKEVAVRIK 282 56666666666666666666667777777777777547778999999976..78888888776 PP == domain 4 score: 36.0 bits; conditional E-value: 3.9e-12 CSDE1 1 erfeGtVvkevpkvdPtksenkglpgeveegiviydekGevytlaftakdvkgkvslqkGdkvkFsisdkkrdgqevAtniel 83 +r+ GtV +++ k+ +k + ++l g++ ++ + + f ++d +g+ sl++Gd v+F+i ++ rd +++Atni l FUN_000352-T1 297 TRYTGTVDRPLSKS-ASKRQHDPLHGKIVYT--VPGNGDTEEEIVFSERDLQGDLSLRTGDIVEFNIAVDCRDLLKRATNISL 376 69************.9*********999888..6666456678**************************************87 PP == domain 5 score: 3.7 bits; conditional E-value: 0.044 CSDE1 55 vslqkGdkvkFsisdkk 71 + q Gd+v+F +s++ FUN_000352-T1 424 HQVQVGDEVEFAVSEDM 440 5689*********9875 PP == domain 6 score: 28.2 bits; conditional E-value: 1e-09 CSDE1 1 erfeGtVvkevpkvdPtksenkglpgeveegiviydekGevytlaftakdvkgkvslqkGdkvkFsisdkkrdgqevAtniel 83 e+++G V++e + t+s+ k e+e g++ +G l+f + + q Gdkv+F++s +r+g ++A n+++ FUN_000352-T1 467 EIYQGLVEREPCYS--TRSPRKD-SRESESGLINSYINGTRESLPFDMTNFEIRAGVQYGDKVEFNLSISQRTGFKRAVNVTV 546 67999999998888..7887775.4679*****9999***************99999************************98 PP == domain 7 score: 27.6 bits; conditional E-value: 1.6e-09 CSDE1 2 rfeGtVvkevpkvdPtksenkglpgeveegiv.iydekG.....ev....ytlaft.akdvkgkvslqkGdkvkFsisdkkrdgqevAtni 81 + G+V + ++ dP + e+ gl+ ++ + +e G e +tl ++ v+ k+ lq G+kv+F+i +++++g+e+A i FUN_000352-T1 631 VYLGKVLRSLRRADPQQAEYSGLIMRIVSDEQdSDEEAGaeeepENqdlpFTLEYGiTSLVDKKTVLQLGEKVRFHIGVDQQTGKERAMKI 721 699********************9887444320233333222114422225555542345788889**********************877 PP == domain 8 score: 25.1 bits; conditional E-value: 9.7e-09 CSDE1 31 giviydekGevytlaftakdvkgkvslqkGdkvkFsisdkkrdgqevAtnie 82 g+++y++ e l f +v+g+v+lq Gd+v+F++ +++++ + +A ++ FUN_000352-T1 740 GFIAYEN-EEGKNLFFHMSEVEGEVELQPGDEVEFVVVQNQKTRKMSACSVR 790 8999997.56667889999***************************998886 PP >> S1-like S1-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.033 71 5 27 .. 53 80 .. 50 94 .. 0.77 2 ! 8.3 0.0 0.0016 3.4 4 31 .. 222 254 .. 220 259 .. 0.74 3 ! 6.7 0.0 0.0048 10 6 42 .. 391 434 .. 389 443 .. 0.80 4 ! 7.6 0.1 0.0025 5.3 5 32 .. 556 588 .. 554 596 .. 0.86 5 ? 3.7 0.1 0.04 86 8 44 .. 732 775 .. 726 785 .. 0.69 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.033 S1-like 5 tGvVTklqdefGfv.....DedVfFqls 27 tGv+ kl +Gf+ D +fF s FUN_000352-T1 53 TGVIEKLLHSYGFIqccerDLRIFFHYS 80 9************944444444555555 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0016 S1-like 4 ftGvVTklqdefGfvD.....edVfFqlsvvkG 31 + GvV ++++ fGf+ ++fF s G FUN_000352-T1 222 YQGVVSSMKESFGFIEradkvSEIFFHYSEFCG 254 78*************733333477777776555 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0048 S1-like 6 GvVTklqdefGfv.....DedVfFqlsvv..kGrlPqvgdkVLv 42 GvV +l++ fGf+ D fF s + G+ qvgd V + FUN_000352-T1 391 GVVASLKEGFGFIrccdrDARMFFHFSELldSGHQVQVGDEVEF 434 9***********98886666789999984347999999999855 PP == domain 4 score: 7.6 bits; conditional E-value: 0.0025 S1-like 5 tGvVTklqdefGfv.....DedVfFqlsvvkGr 32 G V l+++fGf+ D++VfF s G FUN_000352-T1 556 KGFVATLKENFGFLetsehDKEVFFHYSEFDGD 588 599**********87777799*****9987775 PP == domain 5 score: 3.7 bits; conditional E-value: 0.04 S1-like 8 VTklqdefGfv......DedVfFqlsvvkGrlP.qvgdkVLveA 44 V +l+++fGf+ ++ fF +s v+G++ q gd V + FUN_000352-T1 732 VESLKGQFGFIayeneeGKNLFFHMSEVEGEVElQPGDEVEFVV 775 678999999994432222459*********98535677775555 PP >> SUZ-C SUZ-C motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 1.1 5.2e-08 0.00011 7 25 .] 818 836 .. 814 836 .. 0.86 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 5.2e-08 SUZ-C 7 nvlRQPrGPDGskGFrqrR 25 v+R P+GPDG++GF q R FUN_000352-T1 818 EVIRKPTGPDGTRGFAQPR 836 69*************9965 PP >> S1 S1 RNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.16 3.3e+02 30 61 .. 75 101 .. 66 112 .. 0.77 2 ? 2.5 0.0 0.13 2.8e+02 38 61 .. 176 199 .. 173 210 .. 0.83 3 ? 0.6 0.2 0.49 1e+03 6 62 .. 220 284 .. 217 290 .. 0.69 4 ? 5.5 0.0 0.015 32 9 61 .. 390 438 .. 383 450 .. 0.80 5 ? -2.3 0.0 3.9 8.3e+03 44 59 .. 692 707 .. 688 720 .. 0.81 6 ! 9.5 0.3 0.00081 1.7 21 71 .. 731 787 .. 710 790 .. 0.65 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.16 S1 30 gfvpiselssdhvedpdevvkvGdevkvkvlk 61 +f + s++ d e ++vGde++++v+ FUN_000352-T1 75 IFFHYSQINED-----PEDLHVGDELEFEVTS 101 56666777754.....7899**********86 PP == domain 2 score: 2.5 bits; conditional E-value: 0.13 S1 38 ssdhvedpdevvkvGdevkvkvlk 61 ss++v + ++ +++Gd+v+++v+ FUN_000352-T1 176 SSNDVVNTGTPLHKGDKVEFYVTT 199 677788999999**********85 PP == domain 3 score: 0.6 bits; conditional E-value: 0.49 S1 6 evveGeVtrvtk.gGafVelgngvegfvpiselssd.......hvedpdevvkvGdevkvkvlkv 62 e+++G+V++ + +G++ + + e+f + se+ + ++ + + +v+ G+ev v++ k+ FUN_000352-T1 220 ERYQGVVSSMKEsFGFIERADKVSEIFFHYSEFCGEvselmlcDDVEFGIQVRNGKEVAVRIKKL 284 56777777776667777777766667777777666666666656666677778888888888775 PP == domain 4 score: 5.5 bits; conditional E-value: 0.015 S1 9 eGeVtrvtkgGafVelg.ngvegfvpiselssdhvedpdevvkvGdevkvkvlk 61 +G+V ++ +g f++ +++ f + sel + ++ +v+vGdev++ v + FUN_000352-T1 390 MGVVASLKEGFGFIRCCdRDARMFFHFSELLD-----SGHQVQVGDEVEFAVSE 438 68888888877788887789999999999995.....899**********9976 PP == domain 5 score: -2.3 bits; conditional E-value: 3.9 S1 44 dpdevvkvGdevkvkv 59 d+++v++ G++v++ + FUN_000352-T1 692 DKKTVLQLGEKVRFHI 707 6789999999999976 PP == domain 6 score: 9.5 bits; conditional E-value: 0.00081 S1 21 fVelgngvegfvpiselssd......hvedpdevvkvGdevkvkvlkvdkdrrriil 71 +Ve g+ gf+ ++ + + + + + ++++Gdev+++v + k+r+ FUN_000352-T1 731 RVESLKGQFGFIAYENEEGKnlffhmSEVEGEVELQPGDEVEFVVVQNQKTRKMSAC 787 4444444444444444444444444444449999*****************995555 PP >> Rho_RNA_bind Rho termination factor, RNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.27 5.8e+02 2 34 .. 53 82 .. 52 113 .. 0.70 2 ? -0.4 0.0 0.7 1.5e+03 2 17 .. 223 238 .. 222 244 .. 0.86 3 ? 0.9 0.0 0.26 5.6e+02 37 50 .. 348 361 .. 333 383 .. 0.76 4 ? 3.1 0.0 0.057 1.2e+02 3 17 .. 391 405 .. 389 412 .. 0.88 5 ? 2.7 0.0 0.075 1.6e+02 2 20 .. 556 574 .. 555 582 .. 0.84 6 ? 1.5 0.0 0.18 3.8e+02 26 60 .. 751 786 .. 731 797 .. 0.63 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.27 Rho_RNA_bind 2 eGvLeiledgyGFlrssnylpspddiYVsasqi 34 +Gv+e l + yGF++ + + i+ + sqi FUN_000352-T1 53 TGVIEKLLHSYGFIQCC---ERDLRIFFHYSQI 82 699***********974...4444555555555 PP == domain 2 score: -0.4 bits; conditional E-value: 0.7 Rho_RNA_bind 2 eGvLeiledgyGFlrs 17 +Gv+ +++ +GF+ + FUN_000352-T1 223 QGVVSSMKESFGFIER 238 799**********975 PP == domain 3 score: 0.9 bits; conditional E-value: 0.26 Rho_RNA_bind 37 fgLrtGDaveGqvr 50 + LrtGD+ve ++ FUN_000352-T1 348 LSLRTGDIVEFNIA 361 68*******97665 PP == domain 4 score: 3.1 bits; conditional E-value: 0.057 Rho_RNA_bind 3 GvLeiledgyGFlrs 17 Gv+ l++g+GF+r FUN_000352-T1 391 GVVASLKEGFGFIRC 405 89999********96 PP == domain 5 score: 2.7 bits; conditional E-value: 0.075 Rho_RNA_bind 2 eGvLeiledgyGFlrssny 20 +G++ l++++GFl +s++ FUN_000352-T1 556 KGFVATLKENFGFLETSEH 574 689999********99865 PP == domain 6 score: 1.5 bits; conditional E-value: 0.18 Rho_RNA_bind 26 diYVsasqir.rfgLrtGDaveGqvrppkenekyfa 60 + + ++s + +++L+ GD ve v ++++++k++a FUN_000352-T1 751 NLFFHMSEVEgEVELQPGDEVEFVVVQNQKTRKMSA 786 44445554432689********88888876666654 PP >> MazE_antitoxin Antidote-toxin recognition MazE, bacterial antitoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.1 0.016 33 21 36 .. 88 103 .. 85 104 .. 0.88 2 ? 2.9 0.0 0.071 1.5e+02 22 36 .. 187 201 .. 187 206 .. 0.88 3 ? -2.6 0.0 3.8 8.2e+03 20 30 .. 348 358 .. 347 359 .. 0.87 4 ? 0.9 0.0 0.3 6.4e+02 21 35 .. 425 439 .. 422 441 .. 0.81 5 ? 8.0 0.2 0.0018 3.8 19 36 .. 762 779 .. 757 782 .. 0.84 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.016 MazE_antitoxin 21 glkeGdeveievdgdg 36 +l Gde+e+ev+ d+ FUN_000352-T1 88 DLHVGDELEFEVTSDQ 103 7999********9997 PP == domain 2 score: 2.9 bits; conditional E-value: 0.071 MazE_antitoxin 22 lkeGdeveievdgdg 36 l +Gd+ve++v+ d+ FUN_000352-T1 187 LHKGDKVEFYVTTDK 201 578********9997 PP == domain 3 score: -2.6 bits; conditional E-value: 3.8 MazE_antitoxin 20 lglkeGdevei 30 l l+ Gd ve+ FUN_000352-T1 348 LSLRTGDIVEF 358 67999****97 PP == domain 4 score: 0.9 bits; conditional E-value: 0.3 MazE_antitoxin 21 glkeGdeveievdgd 35 ++ Gdeve+ v +d FUN_000352-T1 425 QVQVGDEVEFAVSED 439 6889*****987766 PP == domain 5 score: 8.0 bits; conditional E-value: 0.0018 MazE_antitoxin 19 alglkeGdeveievdgdg 36 + l++Gdeve++v+ ++ FUN_000352-T1 762 EVELQPGDEVEFVVVQNQ 779 6789*********99987 PP >> DUF2196 Uncharacterized conserved protein (DUF2196) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.093 2e+02 6 27 .. 87 108 .. 83 119 .. 0.86 2 ? 1.3 0.0 0.22 4.7e+02 8 26 .. 187 205 .. 181 211 .. 0.88 3 ? -3.2 0.0 5.4 1.1e+04 8 20 .. 271 283 .. 270 310 .. 0.73 4 ? 0.3 0.1 0.46 9.7e+02 7 31 .. 425 449 .. 422 458 .. 0.78 5 ? 3.1 0.0 0.058 1.2e+02 5 45 .. 517 557 .. 513 565 .. 0.80 6 ? 1.6 0.1 0.18 3.8e+02 7 27 .. 696 716 .. 691 722 .. 0.87 7 ? 5.2 0.0 0.013 28 7 35 .. 764 792 .. 759 797 .. 0.88 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.093 DUF2196 6 kdikpGleVeIvlkkdqrtGkl 27 +d++ G+e e+ + dqrtGk FUN_000352-T1 87 EDLHVGDELEFEVTSDQRTGKP 108 7899****************96 PP == domain 2 score: 1.3 bits; conditional E-value: 0.22 DUF2196 8 ikpGleVeIvlkkdqrtGk 26 +++G++Ve+ + +d+rtG FUN_000352-T1 187 LHKGDKVEFYVTTDKRTGV 205 799**************95 PP == domain 3 score: -3.2 bits; conditional E-value: 5.4 DUF2196 8 ikpGleVeIvlkk 20 ++ G eV++ kk FUN_000352-T1 271 VRNGKEVAVRIKK 283 6778888877765 PP == domain 4 score: 0.3 bits; conditional E-value: 0.46 DUF2196 7 dikpGleVeIvlkkdqrtGklteGi 31 +++ G+eVe+ + +d + k+ +G+ FUN_000352-T1 425 QVQVGDEVEFAVSEDMSANKRIHGV 449 7899999999999998888888886 PP == domain 5 score: 3.1 bits; conditional E-value: 0.058 DUF2196 5 rkdikpGleVeIvlkkdqrtGklteGiVkdilTksstHphG 45 r+ ++ G++Ve+ l qrtG + V i +s+ ++G FUN_000352-T1 517 RAGVQYGDKVEFNLSISQRTGFKRAVNVTVIKRNSEVRHKG 557 78899****************88877777777777666666 PP == domain 6 score: 1.6 bits; conditional E-value: 0.18 DUF2196 7 dikpGleVeIvlkkdqrtGkl 27 ++ G +V + dq+tGk+ FUN_000352-T1 696 VLQLGEKVRFHIGVDQQTGKE 716 5789***************97 PP == domain 7 score: 5.2 bits; conditional E-value: 0.013 DUF2196 7 dikpGleVeIvlkkdqrtGklteGiVkdi 35 +++pG+eVe+v+ ++q+t k V++i FUN_000352-T1 764 ELQPGDEVEFVVVQNQKTRKMSACSVRRI 792 789***************99998888877 PP >> Poly_export Polysaccharide biosynthesis/export protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.0 0.0023 4.8 8 41 .. 425 463 .. 420 468 .. 0.85 2 ? 2.2 0.0 0.14 2.9e+02 3 24 .. 759 780 .. 757 795 .. 0.80 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0023 Poly_export 8 rlgpgDvlritvwgepels.......eevtVdpdGtIslPl 41 ++++gD+++ v + ++s +v+V p+GtI++ FUN_000352-T1 425 QVQVGDEVEFAVSE--DMSankrihgVRVRVLPKGTIQMEN 463 7899********66..77777*****55*********9976 PP == domain 2 score: 2.2 bits; conditional E-value: 0.14 Poly_export 3 aasdyrlgpgDvlritvwgepe 24 ++ + l+pgD+++ v ++++ FUN_000352-T1 759 VEGEVELQPGDEVEFVVVQNQK 780 567889*********9999765 PP >> PHA_gran_rgn Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.00014 0.3 13 56 .. 723 768 .. 716 775 .. 0.85 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00014 PHA_gran_rgn 13 eareaaeklaekleeefgl.eiewe.gdtlsfkrsgvkGklevepd 56 ++r+++ + +e l+ +fg+ ++e e g++l f+ s v+G++e++p+ FUN_000352-T1 723 SVRQRVRARVESLKGQFGFiAYENEeGKNLFFHMSEVEGEVELQPG 768 589**************751555558*****************996 PP >> Cyclophil_like2 Cyclophilin-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.00012 0.25 7 70 .. 266 330 .. 260 331 .. 0.82 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00012 Cyclophil_like2 7 eftaelndnaaarallalLP.ltltmedyggnEkiaylpeklstegapegddieaGdlayyapwg 70 ef +++ + + + +++LP t+++ed+ ++ ++++ +++ls ++++++ d+ G ++y p++ FUN_000352-T1 266 EFGIQVRNGKEVAVRIKKLPeGTVKFEDVSTTRYTGTVDRPLSKSASKRQHDPLHGKIVYTVPGN 330 55566656555555678887358*************************************99954 PP >> OB_RNB Ribonuclease B OB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.3 2.7e+03 18 30 .. 22 34 .. 19 37 .. 0.79 2 ? 1.7 0.2 0.14 3e+02 1 23 [. 224 246 .. 224 252 .. 0.86 3 ? 5.4 0.3 0.0098 21 1 50 [. 391 445 .. 391 453 .. 0.69 4 ? 3.0 0.7 0.057 1.2e+02 2 25 .. 558 581 .. 557 587 .. 0.80 5 ? 2.1 0.0 0.11 2.2e+02 2 51 .. 731 785 .. 730 792 .. 0.70 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.3 OB_RNB 18 geeDifIppeqmk 30 eD++I +++ + FUN_000352-T1 22 FNEDYYIGNHNAR 34 579*****99866 PP == domain 2 score: 1.7 bits; conditional E-value: 0.14 OB_RNB 1 GtvrahkkGFGFlipdegeeDif 23 G+v++ k+ FGF++ ++ ++if FUN_000352-T1 224 GVVSSMKESFGFIERADKVSEIF 246 8999*********9988888888 PP == domain 3 score: 5.4 bits; conditional E-value: 0.0098 OB_RNB 1 GtvrahkkGFGFlipdegeeDifIppeqmkkamh....GDrVlvritk.gdrrgr 50 G+v + k+GFGF+++ + + +f + +++ h GD V+ +++ ++ +r FUN_000352-T1 391 GVVASLKEGFGFIRCCDRDARMFFHFSELLDSGHqvqvGDEVEFAVSEdMSANKR 445 889999********98878888877777765555444467777666666665555 PP == domain 4 score: 3.0 bits; conditional E-value: 0.057 OB_RNB 2 tvrahkkGFGFlipdegeeDifIp 25 v + k+ FGFl++ e ++++f + FUN_000352-T1 558 FVATLKENFGFLETSEHDKEVFFH 581 56677899********99999965 PP == domain 5 score: 2.1 bits; conditional E-value: 0.11 OB_RNB 2 tvrahkkGFGFlipde.geeDifIppeqmkkamh...GDrVlvritk.gdrrgrr 51 +v++ k FGF+ + + + +f + +++++ GD V+ + + ++ r+ + FUN_000352-T1 731 RVESLKGQFGFIAYENeEGKNLFFHMSEVEGEVElqpGDEVEFVVVQnQKTRKMS 785 567777789****999999999999998887554444888876666656666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (876 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 546 (0.021374); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 8352.59 // Query: FUN_000355-T1 [L=244] Description: FUN_000355 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (244 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 958 (0.0375024); expected 510.9 (0.02) Passed bias filter: 633 (0.0247798); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2394.06 // Query: FUN_000356-T1 [L=500] Description: FUN_000356 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-10 40.3 0.1 1.4e-09 38.7 0.1 1.8 1 Ig_3 Immunoglobulin domain 4.9e-09 36.8 0.1 1.1e-08 35.6 0.1 1.6 1 Ig_2 Immunoglobulin domain 4.9e-08 33.4 0.4 1.5e-07 31.8 0.4 1.9 1 I-set Immunoglobulin I-set domain 0.00012 22.8 0.3 0.00044 21.0 0.3 2.0 1 ig Immunoglobulin domain 0.00082 20.0 1.5 0.8 10.4 0.1 2.5 2 V-set Immunoglobulin V-set domain ------ inclusion threshold ------ 0.025 14.9 0.1 0.068 13.5 0.1 1.8 1 Ig_6 Immunoglobulin domain 0.03 15.4 0.7 0.066 14.3 0.7 1.6 1 Ig_4 T-cell surface glycoprotein CD3 delta chain Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.7 0.1 3.9e-13 1.4e-09 3 76 .. 318 381 .. 318 382 .. 0.88 Alignments for each domain: == domain 1 score: 38.7 bits; conditional E-value: 3.9e-13 Ig_3 3 vitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvA 76 +i v+p+s++ +eg++v+L+Cea+gn +++W+k+g+ + +++ + L +++v+ d G+Y C++ FUN_000356-T1 318 KIAVQPQSQTKKEGSRVELRCEATGNKL-SYSWLKDGQ---E---M---EGQRGCCLVFEQVNMADFGSYVCQV 381 5889*******************77665.8********...5...2...356899*****************98 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.6 0.1 3e-12 1.1e-08 5 79 .] 322 397 .. 317 397 .. 0.87 Alignments for each domain: == domain 1 score: 35.6 bits; conditional E-value: 3e-12 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn..fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++++++ eg+ v L+C+a gn + +y+w kdg++++ ++ ++ +v+ d G Y C+++ ++++++s e+ v FUN_000356-T1 322 QPQSQTKKEGSRVELRCEATGN-KLSYSWLKDGQEMEGQRGccLVFEQVNMADFGSYVCQVKKKDQSCSSEVAELDV 397 45557789*************9.9*************777775555************************9999876 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.8 0.4 4.2e-11 1.5e-07 2 86 .. 318 392 .. 317 397 .. 0.87 Alignments for each domain: == domain 1 score: 31.8 bits; conditional E-value: 4.2e-11 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasa 86 k+ ++++++ keG+++el c+++G+ +++ sWlkdg+e++ +++ + L++++v+++D G+Y c+++ + +++++++ FUN_000356-T1 318 KIAVQPQSQTKKEGSRVELRCEATGN-KLSYSWLKDGQEMEG-------QRG--CCLVFEQVNMADFGSYVCQVKKKDQSCSSEV 392 577899********************.77************6.......445..8999999**************9977776654 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.3 1.2e-07 0.00044 2 75 .. 325 386 .. 324 392 .. 0.90 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1.2e-07 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpgg 75 + t +eG++++L+C+a+ +++W k+g++++ ++ + l + +v + d G Y C+v + FUN_000356-T1 325 SQTKKEGSRVELRCEAT--GNKLSYSWLKDGQEMEGQR----------GCCLVFEQVNMADFGSYVCQVKKKDQ 386 67889************..999**************95..........5********************98765 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.2 0.00046 1.7 2 43 .. 322 360 .. 321 368 .. 0.78 2 ! 10.4 0.1 0.00022 0.8 75 108 .. 364 397 .. 356 398 .. 0.83 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00046 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrqppgk.ept 43 +p++ t+ eG +v+L+C+ + + s++W ++ ++ +++ FUN_000356-T1 322 QPQSQTKKEGSRVELRCEATGN----KLSYSWLKDGQEMeGQR 360 69999************88865....99*****9887655444 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00022 V-set 75 ltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 l +++++++D G+Y C+v +k+++ +++ +L V FUN_000356-T1 364 LVFEQVNMADFGSYVCQVKKKDQSCSSEVAELDV 397 7789*************98888877877777766 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 1.9e-05 0.068 69 103 .. 358 389 .. 319 405 .. 0.81 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.9e-05 Ig_6 69 ileknaLrfkpvkvndsGlYiCrprirspqekacc 103 + + L f+ v++ d G+Y+C++ ++++++c FUN_000356-T1 358 GQRGCCLVFEQVNMADFGSYVCQV---KKKDQSCS 389 478899****************93...44666664 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.7 1.8e-05 0.066 3 55 .. 333 387 .. 331 395 .. 0.82 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.8e-05 Ig_4 3 kVlLtCnsss..keitwlkdgkeikeskektldlgksiedprglYqCkeeekkks 55 +V L+C+ + ++ wlkdg+e++ ++ l +++ + g Y+C+ ++k++s FUN_000356-T1 333 RVELRCEATGnkLSYSWLKDGQEMEGQRGCCLVFEQVNMADFGSYVCQVKKKDQS 387 799***766533579**************9999****99*********6566655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (500 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 800 (0.0313173); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4859.49 // Query: FUN_000356-T2 [L=502] Description: FUN_000356 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-10 40.3 0.1 1.4e-09 38.7 0.1 1.8 1 Ig_3 Immunoglobulin domain 4.9e-09 36.8 0.1 1.1e-08 35.6 0.1 1.6 1 Ig_2 Immunoglobulin domain 5e-08 33.4 0.4 1.5e-07 31.8 0.4 1.8 1 I-set Immunoglobulin I-set domain 0.00012 22.7 0.3 0.00044 21.0 0.3 2.0 1 ig Immunoglobulin domain 0.00085 20.0 1.5 0.8 10.4 0.1 2.5 2 V-set Immunoglobulin V-set domain ------ inclusion threshold ------ 0.026 14.9 0.1 0.068 13.5 0.1 1.8 1 Ig_6 Immunoglobulin domain 0.03 15.4 0.7 0.067 14.3 0.7 1.6 1 Ig_4 T-cell surface glycoprotein CD3 delta chain Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.7 0.1 3.9e-13 1.4e-09 3 76 .. 318 381 .. 318 382 .. 0.88 Alignments for each domain: == domain 1 score: 38.7 bits; conditional E-value: 3.9e-13 Ig_3 3 vitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvA 76 +i v+p+s++ +eg++v+L+Cea+gn +++W+k+g+ + +++ + L +++v+ d G+Y C++ FUN_000356-T2 318 KIAVQPQSQTKKEGSRVELRCEATGNKL-SYSWLKDGQ---E---M---EGQRGCCLVFEQVNMADFGSYVCQV 381 5889*******************77665.8********...5...2...356899*****************98 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.6 0.1 3.1e-12 1.1e-08 5 79 .] 322 397 .. 317 397 .. 0.87 Alignments for each domain: == domain 1 score: 35.6 bits; conditional E-value: 3.1e-12 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn..fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++++++ eg+ v L+C+a gn + +y+w kdg++++ ++ ++ +v+ d G Y C+++ ++++++s e+ v FUN_000356-T2 322 QPQSQTKKEGSRVELRCEATGN-KLSYSWLKDGQEMEGQRGccLVFEQVNMADFGSYVCQVKKKDQSCSSEVAELDV 397 45557789*************9.9*************777775555************************9999876 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.8 0.4 4.2e-11 1.5e-07 2 86 .. 318 392 .. 317 397 .. 0.87 Alignments for each domain: == domain 1 score: 31.8 bits; conditional E-value: 4.2e-11 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasa 86 k+ ++++++ keG+++el c+++G+ +++ sWlkdg+e++ +++ + L++++v+++D G+Y c+++ + +++++++ FUN_000356-T2 318 KIAVQPQSQTKKEGSRVELRCEATGN-KLSYSWLKDGQEMEG-------QRG--CCLVFEQVNMADFGSYVCQVKKKDQSCSSEV 392 577899********************.77************6.......445..8999999**************9977776654 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.3 1.2e-07 0.00044 2 75 .. 325 386 .. 324 392 .. 0.90 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1.2e-07 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpgg 75 + t +eG++++L+C+a+ +++W k+g++++ ++ + l + +v + d G Y C+v + FUN_000356-T2 325 SQTKKEGSRVELRCEAT--GNKLSYSWLKDGQEMEGQR----------GCCLVFEQVNMADFGSYVCQVKKKDQ 386 67889************..999**************95..........5********************98765 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.2 0.00046 1.7 2 43 .. 322 360 .. 321 368 .. 0.78 2 ! 10.4 0.1 0.00022 0.8 75 108 .. 364 397 .. 356 398 .. 0.83 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00046 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrqppgk.ept 43 +p++ t+ eG +v+L+C+ + + s++W ++ ++ +++ FUN_000356-T2 322 QPQSQTKKEGSRVELRCEATGN----KLSYSWLKDGQEMeGQR 360 69999************88865....99*****9887655444 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00022 V-set 75 ltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 l +++++++D G+Y C+v +k+++ +++ +L V FUN_000356-T2 364 LVFEQVNMADFGSYVCQVKKKDQSCSSEVAELDV 397 7789*************98888877877777766 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 1.9e-05 0.068 69 103 .. 358 389 .. 319 405 .. 0.81 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.9e-05 Ig_6 69 ileknaLrfkpvkvndsGlYiCrprirspqekacc 103 + + L f+ v++ d G+Y+C++ ++++++c FUN_000356-T2 358 GQRGCCLVFEQVNMADFGSYVCQV---KKKDQSCS 389 478899****************93...44666664 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.7 1.8e-05 0.067 3 55 .. 333 387 .. 331 395 .. 0.82 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.8e-05 Ig_4 3 kVlLtCnsss..keitwlkdgkeikeskektldlgksiedprglYqCkeeekkks 55 +V L+C+ + ++ wlkdg+e++ ++ l +++ + g Y+C+ ++k++s FUN_000356-T2 333 RVELRCEATGnkLSYSWLKDGQEMEGQRGCCLVFEQVNMADFGSYVCQVKKKDQS 387 799***766533579**************9999****99*********6566655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (502 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 819 (0.0320611); expected 510.9 (0.02) Passed bias filter: 654 (0.0256019); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.34u 0.41s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 4952.34 // Query: FUN_000357-T1 [L=177] Description: FUN_000357 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.01 16.7 0.1 0.015 16.2 0.1 1.2 1 Mog1 Ran-interacting Mog1 protein Domain annotation for each model (and alignments): >> Mog1 Ran-interacting Mog1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.2 0.1 5.8e-07 0.015 77 131 .. 12 65 .. 1 68 [. 0.66 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 5.8e-07 Mog1 77 eveevekllakeeeasaitligtqkvakfnkeaekeetvavllaliRleevetDi 131 + ++++ +k+ + + + ++ ++v+k +ke+ +e++v+++++liRl+e+e + FUN_000357-T1 12 TPLTFDEYREKKGKERSSRFVSSKSVKKGKKEN-NESEVTIHIGLIRLKEEELKV 65 334444444455566666667777777777766.689************998665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (177 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 650 (0.0254453); expected 510.9 (0.02) Passed bias filter: 458 (0.0179291); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1808.86 // Query: FUN_000359-T1 [L=121] Description: FUN_000359 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.8e-29 100.8 0.6 9.5e-29 100.5 0.6 1.1 1 Ras Ras family 0.00026 21.7 0.1 0.00061 20.5 0.1 1.6 1 Roc Ras of Complex, Roc, domain of DAPkinase ------ inclusion threshold ------ 0.064 13.7 0.6 0.1 13.1 0.6 1.3 1 DUF3963 Protein of unknown function (DUF3963) 0.3 11.9 1.4 6.6 7.6 0.6 2.2 2 KIX KIX domain Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.5 0.6 1.5e-32 9.5e-29 76 161 .. 1 86 [. 1 87 [. 0.98 Alignments for each domain: == domain 1 score: 100.5 bits; conditional E-value: 1.5e-32 Ras 76 llvyditseesfenvkkwleeikrvaeenvpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 +lvydit +sfen+k+w+++i+++a+++v+ +++Gnk+D+e++r+v++++g +la e+++kf+etSAk++ nveeaf +l+r+i+ FUN_000359-T1 1 MLVYDITYDKSFENIKNWIRNIEEHASSDVEKMVLGNKCDMEDRRAVTKDRGTQLATEYEIKFMETSAKSSINVEEAFFTLARDIK 86 79*********************************************************************************986 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.1 9.6e-08 0.00061 84 119 .] 1 40 [. 1 40 [. 0.88 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 9.6e-08 Roc 84 ilvfd...srssenlkeWlkelkevagks.pvilvgnkiD 119 +lv+d ++s+en+k+W+++++e+a+++ +++gnk+D FUN_000359-T1 1 MLVYDityDKSFENIKNWIRNIEEHASSDvEKMVLGNKCD 40 589998777899*************99774789******9 PP >> DUF3963 Protein of unknown function (DUF3963) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.6 1.6e-05 0.1 4 23 .. 3 22 .. 1 24 [. 0.87 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 1.6e-05 DUF3963 4 iyaiFiEkYFgDiqKWiRNi 23 +y i +k F +i+ WiRNi FUN_000359-T1 3 VYDITYDKSFENIKNWIRNI 22 67788899***********9 PP >> KIX KIX domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.02 1.3e+02 35 55 .. 7 27 .. 4 34 .. 0.84 2 ? 7.6 0.6 0.001 6.6 34 80 .. 46 94 .. 30 95 .. 0.75 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.02 KIX 35 lnDkRmeelieyarkvEkeaf 55 +Dk +e++++ +r++E+ a FUN_000359-T1 7 TYDKSFENIKNWIRNIEEHAS 27 689**************9875 PP == domain 2 score: 7.6 bits; conditional E-value: 0.001 KIX 34 alnDkRmeeli.ey.arkvEkeafekakdrdeYYhllaekiyklqKelk 80 a+ R ++l ey ++++E a +++ + ++ l+ + +k+ K+l+ FUN_000359-T1 46 AVTKDRGTQLAtEYeIKFMETSAKSSINVEEAFFTLARDIKLKMDKKLE 94 55555555554133368999999999999999999999999******98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1199 (0.0469368); expected 510.9 (0.02) Passed bias filter: 711 (0.0278332); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.45 # Mc/sec: 1077.58 // Query: FUN_000360-T1 [L=577] Description: FUN_000360 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-06 28.7 0.0 0.048 13.5 0.0 2.4 2 Bact_GSDM Bacterial Gasdermin Family 0.00057 20.3 0.0 1.4 9.3 0.0 2.3 2 A2M_bMG2 Bacterial alpha-2 macroglobulin MG2 domain 0.0016 18.2 0.1 1 9.1 0.0 2.3 2 StiP Tellurite-like stress resistance cysteine protease ------ inclusion threshold ------ 2.1 8.5 4.9 9 6.5 0.6 2.4 2 DUF460 Protein of unknown function (DUF460) 4.8 7.9 4.5 47 4.7 0.4 2.4 2 DUF4514 Domain of unknown function (DUF4514) Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 1.9e-05 0.098 130 160 .. 215 245 .. 186 255 .. 0.74 2 ! 13.5 0.0 9.5e-06 0.048 128 160 .. 454 486 .. 427 503 .. 0.76 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.9e-05 Bact_GSDM 130 kkgelyvitsvlksksfsvtaedengisvel 160 ++++l+++tsv++s++f v e+e++ + ++ FUN_000360-T1 215 QDHDLFLVTSVVYSEKFVVVGEREQKRQSDV 245 6789***************998877665544 PP == domain 2 score: 13.5 bits; conditional E-value: 9.5e-06 Bact_GSDM 128 klkkgelyvitsvlksksfsvtaedengisvel 160 +++el+++tsv++s++f v e+e++ + ++ FUN_000360-T1 454 PYQDHELFLVTSVVYSEKFVVVGEREQKRQSDV 486 45799****************998877665544 PP >> A2M_bMG2 Bacterial alpha-2 macroglobulin MG2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0005 2.5 44 95 .. 203 254 .. 159 256 .. 0.75 2 ! 9.3 0.0 0.00028 1.4 44 95 .. 444 495 .. 407 497 .. 0.78 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0005 A2M_bMG2 44 aelqrreslsyweldellkladlvysgrfdleakknkreklllplkdikelq 95 + + +++ ++ ++l ++++vys +f + ++++++++ ++ ++ ++l+ FUN_000360-T1 203 RAVLDADKMIPYQDHDLFLVTSVVYSEKFVVVGEREQKRQSDVAFDAPEPLK 254 445567789999999************************9999999888887 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00028 A2M_bMG2 44 aelqrreslsyweldellkladlvysgrfdleakknkreklllplkdikelq 95 + + + +++ ++ +el ++++vys +f + ++++++++ ++ ++ ++l+ FUN_000360-T1 444 RAVLNADKMIPYQDHELFLVTSVVYSEKFVVVGEREQKRQSDVAFDAPEPLK 495 45567788999****************************9999999888887 PP >> StiP Tellurite-like stress resistance cysteine protease StiP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.8 0.0 0.00099 5 168 224 .. 158 218 .. 140 231 .. 0.79 2 ! 9.1 0.0 0.0002 1 167 224 .. 398 459 .. 382 472 .. 0.80 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.00099 StiP 168 kleeeLavlaDpagvaelaatreDflip....saiLnstvsGLvSRtvlnedligpedfHg 224 +++++a+ D+++va ++ +D l+ + iL+ + G++SR+vl +d + p + H FUN_000360-T1 158 PVDSDIAIGLDVGSVAGITVIADDILLGrvreEYILDPDLRGILSRAVLDADKMIPYQDHD 218 5788999999****************972222569***************99988888886 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0002 StiP 167 ekleeeLavlaDpagvaelaatreDflip....saiLnstvsGLvSRtvlnedligpedfHg 224 + +++++a+ D+++va ++ +D l+ + iL+ + G++SR+vln+d + p + H FUN_000360-T1 398 APVDSDIAIGVDVGSVAGITVIADDILLGrvreEYILDPDLRGILSRAVLNADKMIPYQDHE 459 3578899999*****************97222256*****************9999888886 PP >> DUF460 Protein of unknown function (DUF460) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.3 0.019 96 9 47 .. 141 178 .. 137 186 .. 0.81 2 ? 6.5 0.6 0.0018 9 5 47 .. 378 419 .. 375 427 .. 0.87 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.019 DUF460 9 vevksvekekiefeplkkkrkkklivGiDPGitvgiail 47 v++k ++++ ie ++ + ++ + +G+D G + gi+++ FUN_000360-T1 141 VKLKVIKEQVIEKGKT-APVDSDIAIGLDVGSVAGITVI 178 6667777777776555.777899*************998 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0018 DUF460 5 kdvqvevksvekekiefeplkkkrkkklivGiDPGitvgiail 47 k++ v++k ++++ ie ++ + ++ + +G+D G + gi+++ FUN_000360-T1 378 KEYAVKLKVIKEQVIEKGKT-APVDSDIAIGVDVGSVAGITVI 419 67889999999999998666.888999*************998 PP >> DUF4514 Domain of unknown function (DUF4514) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.3 0.011 57 5 33 .. 148 177 .. 144 184 .. 0.78 2 ? 4.7 0.4 0.0093 47 5 33 .. 389 418 .. 385 425 .. 0.77 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.011 DUF4514 5 aqvLatGksagaeiDikYal.iGtavGvai 33 qv++ Gk+a + Di l +G+ G+ + FUN_000360-T1 148 EQVIEKGKTAPVDSDIAIGLdVGSVAGITV 177 59*************987665666666665 PP == domain 2 score: 4.7 bits; conditional E-value: 0.0093 DUF4514 5 aqvLatGksagaeiDikYal.iGtavGvai 33 qv++ Gk+a + Di + +G+ G+ + FUN_000360-T1 389 EQVIEKGKTAPVDSDIAIGVdVGSVAGITV 418 59*************976665566666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (577 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 422 (0.0165199); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.50s 00:00:00.84 Elapsed: 00:00:00.55 # Mc/sec: 4255.69 // Query: FUN_000362-T1 [L=1411] Description: FUN_000362 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-235 763.1 3.7 1.9e-14 54.1 0.0 17.7 24 TPR_12 Tetratricopeptide repeat 3.7e-182 584.1 72.8 5.5e-08 32.8 0.1 28.9 29 TPR_1 Tetratricopeptide repeat 7.3e-134 425.5 56.5 3.2e-05 24.2 0.0 29.4 29 TPR_2 Tetratricopeptide repeat 1.3e-122 390.0 6.1 0.00012 22.4 0.0 28.5 28 TPR_7 Tetratricopeptide repeat 8.2e-120 381.4 75.7 0.00022 21.6 0.1 29.3 29 TPR_8 Tetratricopeptide repeat 3.2e-87 284.8 0.1 0.0098 16.4 0.0 26.7 27 TPR_10 Tetratricopeptide repeat 3.5e-57 194.5 30.7 1.9e-09 37.9 0.9 9.8 13 SNAP Soluble NSF attachment protein, SNAP 3.1e-48 165.3 0.0 1.1e-08 35.3 0.0 9.2 9 TPR_MalT MalT-like TPR region 5.9e-42 139.9 3.7 2.8 9.3 0.0 24.3 24 TPR_6 Tetratricopeptide repeat 2.3e-39 133.3 73.7 0.0037 17.4 0.3 30.8 30 TPR_11 TPR repeat 4.8e-36 123.3 0.0 0.035 15.0 0.0 17.9 20 TPR_16 Tetratricopeptide repeat 1.1e-30 103.8 9.6 8.8 7.4 0.0 24.9 25 TPR_17 Tetratricopeptide repeat 4.5e-28 98.3 8.8 8.7 7.1 0.0 21.3 22 DUF7018 Domain of unknown function (DUF7018) 4.6e-25 88.8 24.8 0.048 13.8 0.0 13.7 14 RPN7 26S proteasome subunit RPN7 1.5e-23 81.3 0.0 14 7.2 0.0 19.6 20 TPR_14 Tetratricopeptide repeat 2.7e-22 79.6 17.8 0.037 13.1 0.0 12.1 11 TPR_IF140-IFT172 IF140/IFT172 TPR domain 3.8e-21 75.4 3.0 0.14 12.7 0.1 15.6 16 ANAPC5 Anaphase-promoting complex subunit 5 5e-21 75.0 0.0 12 6.4 0.0 15.1 15 TPR_9 Tetratricopeptide repeat 1.9e-20 73.8 0.0 9 6.6 0.0 17.8 16 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR 1.5e-19 71.2 30.4 0.72 10.2 0.2 15.9 15 ARM_TT21_C Tetratricopeptide repeat protein 21 C-term 4.4e-16 59.7 11.1 18 5.4 0.0 16.2 15 ComR_TPR ComR tetratricopeptide 5.8e-14 52.4 2.3 0.3 11.7 0.0 12.9 17 Rapsyn_N Rapsyn N-terminal myristoylation and linke 2.5e-13 50.6 26.2 4.7 8.1 0.0 14.0 17 ANAPC3 Anaphase-promoting complex, cyclosome, sub 2.6e-12 47.1 33.4 5.8 7.6 0.0 18.0 18 MIT MIT (microtubule interacting and transport 1.5e-11 44.9 21.4 8.7 6.6 0.0 17.1 23 DUF7380 Domain of unknown function (DUF7380) 1.9e-11 44.5 33.9 14 7.0 0.0 20.8 18 Sel1 Sel1 repeat 7.8e-11 41.5 0.5 0.17 10.7 0.0 7.4 7 Cohesin_load Cohesin loading factor 7.2e-10 39.1 0.1 1.6 8.5 0.0 8.3 10 TPR_NPHP3 Nephrocystin-3 TPR domain 2.8e-09 37.5 0.6 85 3.9 0.0 13.2 14 SHPRH_helical-1st E3 ubiquitin-protein ligase SHPRH, first h 3.1e-08 33.9 16.3 1.9 8.4 0.0 9.4 10 RNPP_C RNPP family C-terminal domain 7.2e-07 29.8 0.6 11 6.7 0.1 9.1 10 Cerato-platanin Cerato-platanin 5e-06 27.4 6.7 17 6.3 0.0 9.5 7 Glyoxalase Glyoxalase/Bleomycin resistance protein/Di 6.3e-06 26.4 8.4 64 3.5 0.0 11.3 15 DUF6377 Domain of unknown function (DUF6377) 1.7e-05 24.6 25.5 1.7 8.2 0.2 10.0 12 AimR AimR transcriptional regulator-like 3.8e-05 24.5 23.4 20 5.9 0.1 13.7 15 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth 0.00018 22.0 10.2 1.1e+02 3.3 0.0 10.5 12 Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain 0.00022 21.7 8.6 15 6.2 0.0 9.8 10 HTH_Tnp_Mu_2 Mu DNA binding, I gamma subdomain 0.0023 17.9 30.4 14 5.7 0.0 14.7 15 SHNi-TPR SHNi-TPR ------ inclusion threshold ------ 0.018 15.4 2.0 91 3.4 0.0 6.8 5 Sec8_N Exocyst complex component Sec8 N-terminal 0.022 14.6 2.8 10 5.9 0.0 5.7 6 TPR_leprecan Leprecan family TPR-like repeat region 0.11 12.6 9.5 6.9 6.8 0.0 6.9 6 TPR_21 Tetratricopeptide repeat-like domain 0.2 11.7 0.7 22 5.0 0.0 4.2 5 Foie-gras_1 Foie gras liver health family 1 4.5 7.8 17.3 45 4.5 0.0 8.9 8 DUF627 Protein of unknown function (DUF627) 4.8 8.1 6.9 18 6.2 0.1 5.2 3 DUF1187 Protein of unknown function (DUF1187) Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.2 0.0 8.1e-14 4.7e-11 18 77 .] 32 89 .. 26 89 .. 0.93 2 ! 48.2 0.0 2.3e-15 1.3e-12 5 76 .. 59 128 .. 59 129 .. 0.96 3 ! 32.2 0.0 2.2e-10 1.3e-07 5 77 .] 99 169 .. 95 169 .. 0.95 4 ! 31.0 0.0 5.2e-10 3e-07 5 77 .] 139 209 .. 135 209 .. 0.94 5 ! 38.7 0.0 2e-12 1.2e-09 7 77 .] 181 249 .. 175 249 .. 0.94 6 ! 48.7 0.0 1.6e-15 9.1e-13 4 77 .] 218 289 .. 215 289 .. 0.96 7 ! 48.9 0.0 1.3e-15 7.8e-13 4 77 .] 298 369 .. 295 369 .. 0.95 8 ! 43.1 0.0 9e-14 5.2e-11 8 77 .] 342 409 .. 338 409 .. 0.96 9 ! 40.1 0.0 7.5e-13 4.4e-10 5 76 .. 379 448 .. 375 449 .. 0.94 10 ! 45.5 0.0 1.6e-14 9.1e-12 4 75 .. 418 487 .. 415 489 .. 0.95 11 ! 47.6 0.0 3.5e-15 2e-12 5 77 .] 459 529 .. 455 529 .. 0.95 12 ! 47.9 0.0 2.8e-15 1.6e-12 5 76 .. 499 568 .. 496 569 .. 0.96 13 ! 33.3 0.0 9.9e-11 5.8e-08 4 76 .. 538 608 .. 535 609 .. 0.89 14 ! 11.3 0.0 0.00075 0.43 5 64 .. 579 636 .. 575 638 .. 0.93 15 ! 44.9 0.0 2.4e-14 1.4e-11 6 75 .. 747 814 .. 743 816 .. 0.93 16 ! 47.0 0.0 5.1e-15 3e-12 4 77 .] 825 896 .. 822 896 .. 0.95 17 ! 41.8 0.2 2.2e-13 1.3e-10 4 74 .. 865 933 .. 863 936 .. 0.95 18 ! 37.5 0.0 5.1e-12 2.9e-09 5 77 .] 906 976 .. 900 976 .. 0.94 19 ! 19.7 0.0 1.8e-06 0.001 5 63 .. 946 1002 .. 942 1006 .. 0.90 20 ! 23.0 0.3 1.6e-07 9.3e-05 35 77 .] 1105 1147 .. 1100 1147 .. 0.92 21 ! 54.1 0.0 3.2e-17 1.9e-14 8 77 .] 1160 1227 .. 1153 1227 .. 0.95 22 ! 47.5 0.0 3.8e-15 2.2e-12 4 77 .] 1236 1307 .. 1233 1307 .. 0.96 23 ! 41.4 0.0 3e-13 1.7e-10 8 77 .] 1320 1387 .. 1313 1387 .. 0.94 24 ! 23.8 0.0 9e-08 5.2e-05 5 56 .. 1357 1406 .. 1354 1411 .] 0.90 Alignments for each domain: == domain 1 score: 43.2 bits; conditional E-value: 8.1e-14 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ +++e++ek+l +a + G+d+ + a+ nLgr+y + d+ +A+e++e++l+ia++ FUN_000362-T1 32 DFSKSIECYEKSLKIA--SEGGDRATEGDAYLNLGRVYDSQSDFPKAIECYEESLKIAKE 89 7789************..5679***********************************986 PP == domain 2 score: 48.2 bits; conditional E-value: 2.3e-15 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ v+ + ++ +A+e++e++l +a+++ +d+ a++nLg ++ + d+ + +e++e++l+ia FUN_000362-T1 59 AYLNLGRVYDSQSDFPKAIECYEESLKIAKEA--GDRVRKGKAYFNLGLVFDSQSDFSKSIECYEKSLKIAS 128 588*****************************..99*********************************985 PP == domain 3 score: 32.2 bits; conditional E-value: 2.2e-10 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+ v + ++ +++e++ek+l +a + G+d+ + a+ nL r+y+ + d+++ ++++e++l+ia++ FUN_000362-T1 99 AYFNLGLVFDSQSDFSKSIECYEKSLKIA--SEGGDWATEGDAYLNLRRVYESQSDFAKPIQFYEKSLKIARE 169 7789*************************..5689***********************************986 PP == domain 4 score: 31.0 bits; conditional E-value: 5.2e-10 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++nl v+ + ++++ ++++ek+l +a+++ +d+ l+ + gr+y ++ +A+++++++l+ia+k FUN_000362-T1 139 AYLNLRRVYESQSDFAKPIQFYEKSLKIAREA--GDRALEGVGYLKVGRVYDSESNFPKAIKFYKKSLKIAKK 209 6667778999**********************..99**********************************986 PP == domain 5 score: 38.7 bits; conditional E-value: 2e-12 TPR_12 7 nnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++++ v+ ++ +A+++++k+l +a+++ +d+ ++ a+ Lgr+y +l ++ + +e++e++l ia++ FUN_000362-T1 181 LKVGRVYDSESNFPKAIKFYKKSLKIAKKA--GDRVREIKAYLSLGRVYDTLSNFPKSIECYEKSLTIAKE 249 56788888899*******************..99**********************************986 PP == domain 6 score: 48.7 bits; conditional E-value: 1.6e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++ l+ v+ l ++ +++e++ek+l +a+++ +d+ + a+ nLg +y + d+ +A+e++e++l+ia++ FUN_000362-T1 218 KAYLSLGRVYDTLSNFPKSIECYEKSLTIAKEA--GDRVTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKIARE 289 57888****************************..99**********************************986 PP == domain 7 score: 48.9 bits; conditional E-value: 1.3e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++nl+ v+ +g + +++e++ek+l++a + G+d+ + a +nLg +y + d+ +A+e++e++l+ia++ FUN_000362-T1 298 KAYLNLGLVYGSQGIFGKSIECYEKSLRIA--SEGGDRATEGDAFFNLGLVYDSQSDFPKAVECYEKSLKIAKE 369 5899**************************..5679***********************************986 PP == domain 8 score: 43.1 bits; conditional E-value: 9e-14 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 nl+ v+ + ++ +A e++ek+l +a+++ +d+ l+ a+ nLg ly d+ +A+e+ e++l+ia++ FUN_000362-T1 342 NLGLVYDSQSDFPKAVECYEKSLKIAKEA--GDRTLEGDAYLNLGCLYNSESDFPKAIECDEKSLNIARE 409 9***************************9..999*********************************986 PP == domain 9 score: 40.1 bits; conditional E-value: 7.5e-13 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ ++ ++ +A+e+ ek+l++a+++++p + + a+ nLg +y+ + ++ + +e++e+ l+i + FUN_000362-T1 379 AYLNLGCLYNSESDFPKAIECDEKSLNIAREAGDPVR--EGKAYLNLGLVYFSQSNFPKSIECYEETLKIVR 448 899*****************************77777..999***************************987 PP == domain 10 score: 45.5 bits; conditional E-value: 1.6e-14 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a++nl+ v++ + ++ +++e++e+ l +++++ +d+ + a++nLg +y + ++ + +e++e++l+ a FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLKIVREA--GDRVREGKAYFNLGFVYNSQSEFPKSIECFEKSLKTA 487 5899*****************************..99*******************************9865 PP == domain 11 score: 47.6 bits; conditional E-value: 3.5e-15 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl++v+ + ++ +++e++ek+l a + G d+ + a+ nLgr+y+ + d+ +A+e++e++l+ia++ FUN_000362-T1 459 AYFNLGFVYNSQSEFPKSIECFEKSLKTA--SEGRDRATEGDAYLNLGRVYFSQSDFCKAIECYEESLKIARE 529 788**************************..568************************************986 PP == domain 12 score: 47.9 bits; conditional E-value: 2.8e-15 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++nl+ v++ + ++ +A+e++e++l +a+++ ++++l+ a+ n g ++ +gd+ A+e++e++l+ia FUN_000362-T1 499 AYLNLGRVYFSQSDFCKAIECYEESLKIAREA--GNRDLEGDAYLNVGLFFYSQGDFPIAIECYEKSLKIAS 568 799*****************************..89999******************************985 PP == domain 13 score: 33.3 bits; conditional E-value: 9.9e-11 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a++n++ + + +g++ A+e++ek+l +a + G d+ + ++ nLg +y+ + d+++ e+ e +l ia+ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKSLKIA--SEGVDWATEGKVYLNLGHVYYSQSDFRKETECCENSLSIAK 608 5899**************************..568***********************997777777776665 PP == domain 14 score: 11.3 bits; conditional E-value: 0.00075 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeA 64 +++nl++v++ + ++ + e++e++l +a+++ +d ++ ++ L + y alg+ +A FUN_000362-T1 579 VYLNLGHVYYSQSDFRKETECCENSLSIAKEA--GDQAGVTRVNEFLLDSYTALGNSSKA 636 789**************************999..8899*****************99999 PP == domain 15 score: 44.9 bits; conditional E-value: 2.4e-14 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 + nl+ v++ + ++ +A++++ekal++++++ ++ l+ ++ Lg +y +d+ +A+e++e++l ia FUN_000362-T1 747 YFNLGVVYYSRSEFRKAIKCYEKALNIFTEV--GEQALEGDSYLKLGNAYKSHNDFPKAIECYEKSLIIA 814 569****************************..7788*****************************9666 PP == domain 16 score: 47.0 bits; conditional E-value: 5.1e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a nl+ v+ ++ +A+e++ek+l++a+++ +d+ + +a+ nLg +y + +A +++e++l+ia++ FUN_000362-T1 825 NAFFNLGIVYNSCSDLPKAIEYYEKSLNIAREA--GDKAKEGNAYLNLGNAYMSHDESPKAFNCYEKSLNIARE 896 56679****************************..8999********************************986 PP == domain 17 score: 41.8 bits; conditional E-value: 2.2e-13 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +a++nl+++++ ++ +A+ ++ek+l++a+++ +d+ + a +nLg +yl +gd +A+e++e++l i FUN_000362-T1 865 NAYLNLGNAYMSHDESPKAFNCYEKSLNIAREA--GDRATEGKANYNLGSVYLCRGDRSKAIECYEKSLHI 933 7999*****************************..99*******************************966 PP == domain 18 score: 37.5 bits; conditional E-value: 5.1e-12 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++nl++v++ +g+ +A+e++ek+l +a ++ +d + a+++Lg +y+ + d+ A++++ ++l+ia++ FUN_000362-T1 906 ANYNLGSVYLCRGDRSKAIECYEKSLHIAGEA--GDGTTEGKAYFTLGVVYESRCDLTNAIDCYVKSLNIARE 976 678**************************999..67778*******************************986 PP == domain 19 score: 19.7 bits; conditional E-value: 1.8e-06 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyee 63 a+ l+ v+ + ++++A++++ k+l++a+++ +d+ ++ +a + Lg ylalgd + FUN_000362-T1 946 AYFTLGVVYESRCDLTNAIDCYVKSLNIAREA--GDRTGVNRANQYLGVSYLALGDVLK 1002 6768****************************..88999999************99655 PP == domain 20 score: 23.0 bits; conditional E-value: 1.6e-07 TPR_12 35 rllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + + +d+ a+a++ Lg +yl l d+++A+e++e+ l+ia++ FUN_000362-T1 1105 EDYAGDRATKAEAYFHLGAVYLSLSDFRKAIECHEKGLNIARE 1147 56789999********************************986 PP == domain 21 score: 54.1 bits; conditional E-value: 3.2e-17 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +l+ v++ + ++ +A+e++ek+l++a+++ +d+ + ++nLg++y ++d+ +A+e++e++l+ia++ FUN_000362-T1 1160 HLGTVYHFQSDFPKAIECYEKSLDIAREA--GDRATEGSGYFNLGTVYKSRNDLPKAIEFYEKSLNIARE 1227 79***************************..99**********************************986 PP == domain 22 score: 47.5 bits; conditional E-value: 3.8e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a++nl+ v+ + ++ +A+e++ek+l +a+++ +d+ ++ ++nLg++y ++d+ +A e++e++l+i ++ FUN_000362-T1 1236 KAYLNLGLVYDSQSDFRNAIECYEKSLLIATKA--GDRAAEGSGYFNLGTVYKSRNDLPKAMEFYEKSLNISRE 1307 5899*****************************..99*********************************9875 PP == domain 23 score: 41.4 bits; conditional E-value: 3e-13 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 nl+ ++ + ++ +A+e++ek+l++a ++ +d + a++ Lg++y + +d+++A e++e++l+ia++ FUN_000362-T1 1320 NLGLIYDSQSNFSKAIECYEKSLNIAWEA--GDQATEGKAYFSLGIVYKLHKDFAKAFECFEKSLNIARE 1387 8*************************556..9999********************************986 PP == domain 24 score: 23.8 bits; conditional E-value: 9e-08 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlyl 56 a+ l+ v+ +++++A+e++ek+l++a+++ +dh ++++a + L+ yl FUN_000362-T1 1357 AYFSLGIVYKLHKDFAKAFECFEKSLNIAREA--GDHAGVSRANQYLANSYL 1406 565799**************************..99********99999886 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.003 1.8 14 31 .. 30 47 .. 28 49 .. 0.87 2 ! 28.9 0.0 1.6e-09 9.5e-07 2 31 .. 58 87 .. 57 89 .. 0.95 3 ! 27.0 0.0 6.2e-09 3.6e-06 2 31 .. 98 127 .. 97 129 .. 0.95 4 ? 3.5 0.1 0.18 1e+02 10 31 .. 146 167 .. 138 169 .. 0.85 5 ! 13.8 0.0 9.6e-05 0.056 7 31 .. 183 207 .. 178 209 .. 0.88 6 ! 19.8 0.0 1.2e-06 0.00069 2 31 .. 218 247 .. 217 249 .. 0.94 7 ! 32.8 0.1 9.5e-11 5.5e-08 2 31 .. 258 287 .. 257 289 .. 0.95 8 ! 24.5 0.0 3.8e-08 2.2e-05 2 31 .. 298 327 .. 297 329 .. 0.94 9 ! 29.6 0.0 9.7e-10 5.6e-07 2 31 .. 338 367 .. 337 369 .. 0.95 10 ! 15.0 0.1 4e-05 0.023 2 23 .. 378 399 .. 377 409 .. 0.88 11 ! 26.9 0.0 7.1e-09 4.1e-06 2 30 .. 418 446 .. 417 448 .. 0.96 12 ! 23.8 0.0 6.5e-08 3.8e-05 2 29 .. 458 485 .. 457 489 .. 0.94 13 ! 24.9 0.1 2.9e-08 1.7e-05 2 31 .. 498 527 .. 497 529 .. 0.95 14 ! 24.0 0.0 5.8e-08 3.3e-05 2 31 .. 538 567 .. 537 569 .. 0.95 15 ! 10.0 0.0 0.0015 0.9 2 30 .. 578 606 .. 577 609 .. 0.82 16 ! 29.8 0.2 8.5e-10 5e-07 3 29 .. 746 772 .. 744 774 .. 0.93 17 ! 24.6 0.1 3.6e-08 2.1e-05 2 30 .. 785 813 .. 784 816 .. 0.91 18 ! 22.6 0.1 1.6e-07 9.4e-05 2 31 .. 825 854 .. 824 856 .. 0.92 19 ! 18.2 0.2 4e-06 0.0023 2 31 .. 865 894 .. 864 896 .. 0.92 20 ! 21.6 0.1 3.1e-07 0.00018 2 30 .. 905 933 .. 904 936 .. 0.92 21 ! 16.5 0.0 1.3e-05 0.0077 2 30 .. 945 973 .. 944 976 .. 0.93 22 ? -1.1 0.1 4.8 2.8e+03 6 17 .. 989 1000 .. 986 1003 .. 0.84 23 ! 24.1 0.1 5.3e-08 3.1e-05 1 30 [. 1115 1144 .. 1115 1147 .. 0.93 24 ! 22.1 0.0 2.2e-07 0.00013 3 31 .. 1157 1185 .. 1155 1187 .. 0.90 25 ! 22.9 0.0 1.3e-07 7.4e-05 3 31 .. 1197 1225 .. 1196 1227 .. 0.92 26 ! 27.5 0.2 4.3e-09 2.5e-06 2 30 .. 1236 1264 .. 1235 1265 .. 0.94 27 ! 20.2 0.0 9.2e-07 0.00053 3 30 .. 1277 1304 .. 1276 1307 .. 0.92 28 ! 28.0 0.2 3.2e-09 1.8e-06 2 30 .. 1316 1344 .. 1315 1345 .. 0.93 29 ! 20.1 0.1 9.5e-07 0.00055 2 31 .. 1356 1385 .. 1355 1387 .. 0.93 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.003 TPR_1 14 lgkydeAleyyekALeln 31 + ++ + +e+yek L++ FUN_000362-T1 30 KSDFSKSIECYEKSLKIA 47 5799************96 PP == domain 2 score: 28.9 bits; conditional E-value: 1.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG +y ++ ++ +A+e+ye+ L++ FUN_000362-T1 58 DAYLNLGRVYDSQSDFPKAIECYEESLKIA 87 79**************************96 PP == domain 3 score: 27.0 bits; conditional E-value: 6.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka++nlG+++ ++ ++ + +e+yek L++ FUN_000362-T1 98 KAYFNLGLVFDSQSDFSKSIECYEKSLKIA 127 79**************************96 PP == domain 4 score: 3.5 bits; conditional E-value: 0.18 TPR_1 10 ayfklgkydeAleyyekALeln 31 +y ++ ++ + +++yek L++ FUN_000362-T1 146 VYESQSDFAKPIQFYEKSLKIA 167 79999999999*********97 PP == domain 5 score: 13.8 bits; conditional E-value: 9.6e-05 TPR_1 7 lGnayfklgkydeAleyyekALeln 31 G +y + ++ +A+++y+k L++ FUN_000362-T1 183 VGRVYDSESNFPKAIKFYKKSLKIA 207 5889*******************96 PP == domain 6 score: 19.8 bits; conditional E-value: 1.2e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka+ lG +y l ++ + +e+yek L++ FUN_000362-T1 218 KAYLSLGRVYDTLSNFPKSIECYEKSLTIA 247 8**************************986 PP == domain 7 score: 32.8 bits; conditional E-value: 9.5e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG++y ++ ++ +A+e+yek L++ FUN_000362-T1 258 DAYLNLGLVYDSQSDFPKAIECYEKSLKIA 287 79**************************97 PP == domain 8 score: 24.5 bits; conditional E-value: 3.8e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka+ nlG++y ++g + + +e+yek L++ FUN_000362-T1 298 KAYLNLGLVYGSQGIFGKSIECYEKSLRIA 327 79*************************986 PP == domain 9 score: 29.6 bits; conditional E-value: 9.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG++y ++ ++ +A+e+yek L++ FUN_000362-T1 338 DAFFNLGLVYDSQSDFPKAVECYEKSLKIA 367 79**************************96 PP == domain 10 score: 15.0 bits; conditional E-value: 4e-05 TPR_1 2 kalynlGnayfklgkydeAley 23 +a+ nlG +y + ++ +A+e+ FUN_000362-T1 378 DAYLNLGCLYNSESDFPKAIEC 399 79*******************9 PP == domain 11 score: 26.9 bits; conditional E-value: 7.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ nlG++yf++ ++ + +e+ye+ L++ FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLKI 446 79***********************9997 PP == domain 12 score: 23.8 bits; conditional E-value: 6.5e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALe 29 ka++nlG +y ++ ++ + +e++ek L+ FUN_000362-T1 458 KAYFNLGFVYNSQSEFPKSIECFEKSLK 485 79************************98 PP == domain 13 score: 24.9 bits; conditional E-value: 2.9e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG +yf++ ++ +A+e+ye+ L++ FUN_000362-T1 498 DAYLNLGRVYFSQSDFCKAIECYEESLKIA 527 79**************************97 PP == domain 14 score: 24.0 bits; conditional E-value: 5.8e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ n G+ ++++g++ A+e+yek L++ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKSLKIA 567 79**************************96 PP == domain 15 score: 10.0 bits; conditional E-value: 0.0015 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k++ nlG++y+++ ++ + e++e L++ FUN_000362-T1 578 KVYLNLGHVYYSQSDFRKETECCENSLSI 606 78**************9866666666665 PP == domain 16 score: 29.8 bits; conditional E-value: 8.5e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALe 29 ++nlG++y++ ++ +A+++yekAL FUN_000362-T1 746 FYFNLGVVYYSRSEFRKAIKCYEKALN 772 69***********************96 PP == domain 17 score: 24.6 bits; conditional E-value: 3.6e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +++ lGnay + +++ +A+e+yek L + FUN_000362-T1 785 DSYLKLGNAYKSHNDFPKAIECYEKSLII 813 57999********************9966 PP == domain 18 score: 22.6 bits; conditional E-value: 1.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a++nlG +y + ++ +A+eyyek L + FUN_000362-T1 825 NAFFNLGIVYNSCSDLPKAIEYYEKSLNIA 854 599***********************9775 PP == domain 19 score: 18.2 bits; conditional E-value: 4e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGnay++ + +A +yek L + FUN_000362-T1 865 NAYLNLGNAYMSHDESPKAFNCYEKSLNIA 894 69************************9775 PP == domain 20 score: 21.6 bits; conditional E-value: 3.1e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka ynlG +y+ g+ +A+e+yek L + FUN_000362-T1 905 KANYNLGSVYLCRGDRSKAIECYEKSLHI 933 577***********************987 PP == domain 21 score: 16.5 bits; conditional E-value: 1.3e-05 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka++ lG++y + ++ A+++y k L + FUN_000362-T1 945 KAYFTLGVVYESRCDLTNAIDCYVKSLNI 973 79***********************9977 PP == domain 22 score: -1.1 bits; conditional E-value: 4.8 TPR_1 6 nlGnayfklgky 17 lG+ y++lg+ FUN_000362-T1 989 YLGVSYLALGDV 1000 59********95 PP == domain 23 score: 24.1 bits; conditional E-value: 5.3e-08 TPR_1 1 akalynlGnayfklgkydeAleyyekALel 30 a+a++ lG++y++l ++ +A+e+ ek L + FUN_000362-T1 1115 AEAYFHLGAVYLSLSDFRKAIECHEKGLNI 1144 89************************9977 PP == domain 24 score: 22.1 bits; conditional E-value: 2.2e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a + lG +y+ + ++ +A+e+yek L + FUN_000362-T1 1157 ASFHLGTVYHFQSDFPKAIECYEKSLDIA 1185 6689**********************986 PP == domain 25 score: 22.9 bits; conditional E-value: 1.3e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++nlG +y + +++ +A+e+yek L + FUN_000362-T1 1197 GYFNLGTVYKSRNDLPKAIEFYEKSLNIA 1225 59***********************9775 PP == domain 26 score: 27.5 bits; conditional E-value: 4.3e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ nlG++y ++ ++ A+e+yek L + FUN_000362-T1 1236 KAYLNLGLVYDSQSDFRNAIECYEKSLLI 1264 79***********************9965 PP == domain 27 score: 20.2 bits; conditional E-value: 9.2e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 ++nlG +y + +++ +A e+yek L + FUN_000362-T1 1277 GYFNLGTVYKSRNDLPKAMEFYEKSLNI 1304 59**********************9976 PP == domain 28 score: 28.0 bits; conditional E-value: 3.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ nlG++y ++ ++ +A+e+yek L + FUN_000362-T1 1316 KACLNLGLIYDSQSNFSKAIECYEKSLNI 1344 799**********************9965 PP == domain 29 score: 20.1 bits; conditional E-value: 9.5e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 ka++ lG +y +++ +A e++ek L + FUN_000362-T1 1356 KAYFSLGIVYKLHKDFAKAFECFEKSLNIA 1385 79************************9775 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.038 22 16 31 .. 32 47 .. 28 49 .. 0.89 2 ! 22.8 0.1 1.6e-07 9.1e-05 2 32 .. 58 88 .. 57 90 .. 0.94 3 ! 18.5 0.0 3.8e-06 0.0022 2 31 .. 98 127 .. 97 129 .. 0.94 4 ? 0.5 0.1 2.3 1.3e+03 10 32 .. 146 168 .. 137 170 .. 0.77 5 ! 10.7 0.0 0.0012 0.69 4 32 .. 180 208 .. 178 210 .. 0.89 6 ! 13.4 0.0 0.00016 0.092 2 32 .. 218 248 .. 217 250 .. 0.92 7 ! 22.9 0.1 1.4e-07 8.2e-05 2 32 .. 258 288 .. 257 290 .. 0.93 8 ! 17.3 0.0 9.2e-06 0.0054 2 31 .. 298 327 .. 297 329 .. 0.94 9 ! 22.3 0.0 2.3e-07 0.00013 2 32 .. 338 368 .. 337 370 .. 0.93 10 ? 2.5 0.0 0.48 2.8e+02 2 31 .. 378 407 .. 377 410 .. 0.83 11 ! 18.5 0.0 3.8e-06 0.0022 2 30 .. 418 446 .. 417 450 .. 0.93 12 ! 12.2 0.0 0.00038 0.22 2 29 .. 458 485 .. 457 489 .. 0.94 13 ! 19.1 0.1 2.4e-06 0.0014 2 32 .. 498 528 .. 497 530 .. 0.93 14 ! 17.4 0.0 8.4e-06 0.0049 2 31 .. 538 567 .. 537 569 .. 0.93 15 ? 2.8 0.0 0.41 2.4e+02 2 19 .. 578 595 .. 577 609 .. 0.81 16 ! 24.2 0.0 5.5e-08 3.2e-05 3 30 .. 746 773 .. 744 776 .. 0.93 17 ! 19.8 0.1 1.4e-06 0.0008 3 31 .. 786 814 .. 784 817 .. 0.90 18 ! 10.8 0.0 0.0011 0.64 3 32 .. 826 855 .. 824 857 .. 0.90 19 ! 15.1 0.1 4.5e-05 0.026 3 32 .. 866 895 .. 864 897 .. 0.92 20 ! 20.9 0.1 6.4e-07 0.00037 2 31 .. 905 934 .. 904 937 .. 0.91 21 ! 14.9 0.0 5.1e-05 0.03 2 32 .. 945 975 .. 944 977 .. 0.93 22 ? 1.7 0.0 0.91 5.3e+02 4 20 .. 987 1003 .. 985 1004 .. 0.85 23 ! 14.0 0.2 0.0001 0.06 1 31 [. 1115 1145 .. 1115 1147 .. 0.91 24 ! 15.9 0.0 2.6e-05 0.015 3 32 .. 1157 1186 .. 1155 1188 .. 0.90 25 ! 18.3 0.0 4.2e-06 0.0025 3 31 .. 1197 1225 .. 1195 1228 .. 0.93 26 ! 18.0 0.1 5.4e-06 0.0031 2 31 .. 1236 1265 .. 1235 1268 .. 0.93 27 ! 16.1 0.0 2.2e-05 0.013 3 31 .. 1277 1305 .. 1275 1308 .. 0.92 28 ! 19.9 0.0 1.3e-06 0.00076 2 30 .. 1316 1344 .. 1315 1345 .. 0.94 29 ! 20.0 0.1 1.2e-06 0.00072 2 32 .. 1356 1386 .. 1355 1388 .. 0.93 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.038 TPR_2 16 dyeeAleayekAleld 31 d+ + +e+yek+l+++ FUN_000362-T1 32 DFSKSIECYEKSLKIA 47 899***********97 PP == domain 2 score: 22.8 bits; conditional E-value: 1.6e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ nlG++y + d+ +A+e+ye++l+++ FUN_000362-T1 58 DAYLNLGRVYDSQSDFPKAIECYEESLKIAK 88 69**************************987 PP == domain 3 score: 18.5 bits; conditional E-value: 3.8e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a++nlGl+ + d+ + +e+yek+l+++ FUN_000362-T1 98 KAYFNLGLVFDSQSDFSKSIECYEKSLKIA 127 79**************************97 PP == domain 4 score: 0.5 bits; conditional E-value: 2.3 TPR_2 10 ayyklgdyeeAleayekAleldP 32 +y+ + d+++ +++yek+l+++ FUN_000362-T1 146 VYESQSDFAKPIQFYEKSLKIAR 168 67777788888899999999875 PP == domain 5 score: 10.7 bits; conditional E-value: 0.0012 TPR_2 4 lynlGlayyklgdyeeAleayekAleldP 32 + G++y ++ +A+++y+k+l+++ FUN_000362-T1 180 YLKVGRVYDSESNFPKAIKFYKKSLKIAK 208 5677999*******************987 PP == domain 6 score: 13.4 bits; conditional E-value: 0.00016 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ lG++y l ++ + +e+yek+l ++ FUN_000362-T1 218 KAYLSLGRVYDTLSNFPKSIECYEKSLTIAK 248 68999**********************9976 PP == domain 7 score: 22.9 bits; conditional E-value: 1.4e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ nlGl+y + d+ +A+e+yek+l+++ FUN_000362-T1 258 DAYLNLGLVYDSQSDFPKAIECYEKSLKIAR 288 69**************************986 PP == domain 8 score: 17.3 bits; conditional E-value: 9.2e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlGl+y +g + + +e+yek+l+++ FUN_000362-T1 298 KAYLNLGLVYGSQGIFGKSIECYEKSLRIA 327 79*************************997 PP == domain 9 score: 22.3 bits; conditional E-value: 2.3e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a +nlGl+y + d+ +A+e+yek+l+++ FUN_000362-T1 338 DAFFNLGLVYDSQSDFPKAVECYEKSLKIAK 368 689*************************987 PP == domain 10 score: 2.5 bits; conditional E-value: 0.48 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlG++y d+ +A+e+ ek+l ++ FUN_000362-T1 378 DAYLNLGCLYNSESDFPKAIECDEKSLNIA 407 689999999999999999999977777665 PP == domain 11 score: 18.5 bits; conditional E-value: 3.8e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ nlGl+y+ + ++ + +e+ye+ l++ FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLKI 446 79***********************9998 PP == domain 12 score: 12.2 bits; conditional E-value: 0.00038 TPR_2 2 ealynlGlayyklgdyeeAleayekAle 29 +a++nlG +y + ++ + +e++ek+l+ FUN_000362-T1 458 KAYFNLGFVYNSQSEFPKSIECFEKSLK 485 79************************98 PP == domain 13 score: 19.1 bits; conditional E-value: 2.4e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+ nlG++y+ + d+ +A+e+ye++l+++ FUN_000362-T1 498 DAYLNLGRVYFSQSDFCKAIECYEESLKIAR 528 69**************************986 PP == domain 14 score: 17.4 bits; conditional E-value: 8.4e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ n Gl y +gd+ A+e+yek+l+++ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKSLKIA 567 6999************************97 PP == domain 15 score: 2.8 bits; conditional E-value: 0.41 TPR_2 2 ealynlGlayyklgdyee 19 +++ nlG +yy + d+ + FUN_000362-T1 578 KVYLNLGHVYYSQSDFRK 595 6899*********99976 PP == domain 16 score: 24.2 bits; conditional E-value: 5.5e-08 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 ++nlG +yy + ++ +A+++yekAl + FUN_000362-T1 746 FYFNLGVVYYSRSEFRKAIKCYEKALNI 773 79************************87 PP == domain 17 score: 19.8 bits; conditional E-value: 1.4e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 + lG+ay +d+ +A+e+yek+l ++ FUN_000362-T1 786 SYLKLGNAYKSHNDFPKAIECYEKSLIIA 814 6889*********************9876 PP == domain 18 score: 10.8 bits; conditional E-value: 0.0011 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a +nlG +y d+ +A+e+yek+l ++ FUN_000362-T1 826 AFFNLGIVYNSCSDLPKAIEYYEKSLNIAR 855 7899**********************9875 PP == domain 19 score: 15.1 bits; conditional E-value: 4.5e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a+ nlG+ay+ + +A ++yek+l ++ FUN_000362-T1 866 AYLNLGNAYMSHDESPKAFNCYEKSLNIAR 895 89************************9875 PP == domain 20 score: 20.9 bits; conditional E-value: 6.4e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a ynlG +y+ +gd +A+e+yek+l ++ FUN_000362-T1 905 KANYNLGSVYLCRGDRSKAIECYEKSLHIA 934 688***********************9775 PP == domain 21 score: 14.9 bits; conditional E-value: 5.1e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a+++lG +y+ + d+ A+++y k+l ++ FUN_000362-T1 945 KAYFTLGVVYESRCDLTNAIDCYVKSLNIAR 975 79*************************9875 PP == domain 22 score: 1.7 bits; conditional E-value: 0.91 TPR_2 4 lynlGlayyklgdyeeA 20 +lG +y++lgd +A FUN_000362-T1 987 NQYLGVSYLALGDVLKA 1003 679**********8777 PP == domain 23 score: 14.0 bits; conditional E-value: 0.0001 TPR_2 1 aealynlGlayyklgdyeeAleayekAleld 31 aea++ lG +y+ l d+ +A+e+ ek l ++ FUN_000362-T1 1115 AEAYFHLGAVYLSLSDFRKAIECHEKGLNIA 1145 89*********************88888765 PP == domain 24 score: 15.9 bits; conditional E-value: 2.6e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a + lG +y + d+ +A+e+yek+l ++ FUN_000362-T1 1157 ASFHLGTVYHFQSDFPKAIECYEKSLDIAR 1186 6699**********************9976 PP == domain 25 score: 18.3 bits; conditional E-value: 4.2e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 +++nlG +y ++d+ +A+e+yek+l ++ FUN_000362-T1 1197 GYFNLGTVYKSRNDLPKAIEFYEKSLNIA 1225 69************************987 PP == domain 26 score: 18.0 bits; conditional E-value: 5.4e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ nlGl+y + d+ A+e+yek+l ++ FUN_000362-T1 1236 KAYLNLGLVYDSQSDFRNAIECYEKSLLIA 1265 79************************9875 PP == domain 27 score: 16.1 bits; conditional E-value: 2.2e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 +++nlG +y ++d+ +A e+yek+l + FUN_000362-T1 1277 GYFNLGTVYKSRNDLPKAMEFYEKSLNIS 1305 69************************986 PP == domain 28 score: 19.9 bits; conditional E-value: 1.3e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ nlGl+y + ++ +A+e+yek+l + FUN_000362-T1 1316 KACLNLGLIYDSQSNFSKAIECYEKSLNI 1344 6999**********************987 PP == domain 29 score: 20.0 bits; conditional E-value: 1.2e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a++ lG +y +d+++A e++ek+l ++ FUN_000362-T1 1356 KAYFSLGIVYKLHKDFAKAFECFEKSLNIAR 1386 79*************************9875 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.72 4.2e+02 13 35 .. 31 53 .. 28 54 .. 0.87 2 ! 22.4 0.0 2e-07 0.00012 1 35 [. 59 93 .. 59 94 .. 0.96 3 ! 10.4 0.0 0.0015 0.86 1 31 [. 99 129 .. 99 132 .. 0.89 4 ! 13.1 0.1 0.00019 0.11 1 36 [] 139 174 .. 139 174 .. 0.96 5 ! 11.6 0.0 0.00061 0.35 6 35 .. 184 213 .. 180 214 .. 0.93 6 ! 14.8 0.0 5.8e-05 0.033 1 35 [. 219 253 .. 219 254 .. 0.96 7 ! 20.1 0.0 1.1e-06 0.00064 1 35 [. 259 293 .. 259 294 .. 0.96 8 ! 8.3 0.0 0.007 4 1 36 [] 299 334 .. 299 334 .. 0.94 9 ! 19.3 0.0 2e-06 0.0012 1 35 [. 339 373 .. 339 374 .. 0.95 10 ! 11.9 0.0 0.00048 0.28 1 35 [. 379 413 .. 379 414 .. 0.95 11 ! 9.1 0.0 0.0037 2.1 1 35 [. 419 453 .. 419 454 .. 0.95 12 ? 3.7 0.0 0.2 1.1e+02 1 35 [. 459 493 .. 459 494 .. 0.87 13 ! 12.6 0.0 0.00028 0.16 1 35 [. 499 533 .. 499 534 .. 0.94 14 ? 5.7 0.0 0.047 27 1 29 [. 539 567 .. 539 570 .. 0.88 15 ? 3.9 0.0 0.18 1e+02 2 35 .. 580 613 .. 579 614 .. 0.89 16 ! 12.6 0.0 0.00028 0.16 3 27 .. 748 772 .. 747 779 .. 0.92 17 ! 14.2 0.0 8.9e-05 0.052 2 34 .. 787 819 .. 786 821 .. 0.91 18 ! 16.1 0.0 2.2e-05 0.013 1 35 [. 826 860 .. 826 861 .. 0.94 19 ! 11.5 0.0 0.00066 0.38 1 36 [] 866 901 .. 866 901 .. 0.96 20 ! 18.4 0.0 3.8e-06 0.0022 3 34 .. 908 939 .. 907 941 .. 0.91 21 ! 8.1 0.0 0.0079 4.6 5 35 .. 950 980 .. 946 981 .. 0.92 22 ! 13.8 0.0 0.00011 0.066 1 35 [. 1117 1151 .. 1117 1152 .. 0.94 23 ! 16.4 0.0 1.7e-05 0.0096 4 36 .] 1160 1192 .. 1157 1192 .. 0.94 24 ! 17.1 0.0 1e-05 0.0059 3 34 .. 1199 1230 .. 1198 1230 .. 0.95 25 ! 19.8 0.1 1.4e-06 0.00083 1 36 [] 1237 1272 .. 1237 1272 .. 0.95 26 ! 14.9 0.0 5.2e-05 0.03 3 36 .] 1279 1312 .. 1278 1312 .. 0.95 27 ! 18.2 0.0 4.4e-06 0.0025 1 29 [. 1317 1345 .. 1317 1352 .. 0.90 28 ? 4.0 0.0 0.16 92 1 34 [. 1357 1390 .. 1357 1392 .. 0.92 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.72 TPR_7 13 GdydeAirlyerlLalakdpedr 35 d+ + i++ye+ L +a + +dr FUN_000362-T1 31 SDFSKSIECYEKSLKIASEGGDR 53 6999***********99999988 PP == domain 2 score: 22.4 bits; conditional E-value: 2e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+r+y ++ d+ +Ai++ye+ L +ak+ +dr FUN_000362-T1 59 AYLNLGRVYDSQSDFPKAIECYEESLKIAKEAGDR 93 789****************************9998 PP == domain 3 score: 10.4 bits; conditional E-value: 0.0015 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+ +L+ ++ ++ d+ + i++ye+ L +a + FUN_000362-T1 99 AYFNLGLVFDSQSDFSKSIECYEKSLKIASE 129 789*********************9988765 PP == domain 4 score: 13.1 bits; conditional E-value: 0.00019 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L r+y+++ d+ + i++ye+ L +a++ +dr+ FUN_000362-T1 139 AYLNLRRVYESQSDFAKPIQFYEKSLKIAREAGDRA 174 789*****************************9985 PP == domain 5 score: 11.6 bits; conditional E-value: 0.00061 TPR_7 6 ariyrklGdydeAirlyerlLalakdpedr 35 +r+y ++ ++ +Ai++y++ L +ak+ +dr FUN_000362-T1 184 GRVYDSESNFPKAIKFYKKSLKIAKKAGDR 213 9*************************9998 PP == domain 6 score: 14.8 bits; conditional E-value: 5.8e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+r+y l ++ + i++ye+ L++ak+ +dr FUN_000362-T1 219 AYLSLGRVYDTLSNFPKSIECYEKSLTIAKEAGDR 253 7899***************************9998 PP == domain 7 score: 20.1 bits; conditional E-value: 1.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y ++ d+ +Ai++ye+ L +a++ +dr FUN_000362-T1 259 AYLNLGLVYDSQSDFPKAIECYEKSLKIAREAGDR 293 789****************************9998 PP == domain 8 score: 8.3 bits; conditional E-value: 0.007 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +y ++G + + i++ye+ L++a + +dr+ FUN_000362-T1 299 AYLNLGLVYGSQGIFGKSIECYEKSLRIASEGGDRA 334 789**************************9999985 PP == domain 9 score: 19.3 bits; conditional E-value: 2e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y ++ d+ +A+++ye+ L +ak+ +dr FUN_000362-T1 339 AFFNLGLVYDSQSDFPKAVECYEKSLKIAKEAGDR 373 678****************************9998 PP == domain 10 score: 11.9 bits; conditional E-value: 0.00048 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y ++ d+ +Ai++ e+ L +a++ +d+ FUN_000362-T1 379 AYLNLGCLYNSESDFPKAIECDEKSLNIAREAGDP 413 789***************************99997 PP == domain 11 score: 9.1 bits; conditional E-value: 0.0037 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y ++ ++ + i++ye+ L ++++ +dr FUN_000362-T1 419 AYLNLGLVYFSQSNFPKSIECYEETLKIVREAGDR 453 789***************************99998 PP == domain 12 score: 3.7 bits; conditional E-value: 0.2 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y ++ ++ + i+++e+ L +a + +dr FUN_000362-T1 459 AYFNLGFVYNSQSEFPKSIECFEKSLKTASEGRDR 493 6889999*****************99888777766 PP == domain 13 score: 12.6 bits; conditional E-value: 0.00028 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+r+y ++ d+ +Ai++ye+ L +a++ ++r FUN_000362-T1 499 AYLNLGRVYFSQSDFCKAIECYEESLKIAREAGNR 533 789**************************998876 PP == domain 14 score: 5.7 bits; conditional E-value: 0.047 TPR_7 1 aLsaLariyrklGdydeAirlyerlLala 29 a+++ + ++ ++Gd+ Ai++ye+ L +a FUN_000362-T1 539 AYLNVGLFFYSQGDFPIAIECYEKSLKIA 567 6789999*****************88765 PP == domain 15 score: 3.9 bits; conditional E-value: 0.18 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L+++y ++ d+++ +++e+ L++ak+ +d+ FUN_000362-T1 580 YLNLGHVYYSQSDFRKETECCENSLSIAKEAGDQ 613 689************9999999999999998886 PP == domain 16 score: 12.6 bits; conditional E-value: 0.00028 TPR_7 3 saLariyrklGdydeAirlyerlLa 27 +L+ +y ++ ++++Ai++ye++L FUN_000362-T1 748 FNLGVVYYSRSEFRKAIKCYEKALN 772 69********************885 PP == domain 17 score: 14.2 bits; conditional E-value: 8.9e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdped 34 ++ L+++y + +d+ +Ai++ye+ L +a++ +d FUN_000362-T1 787 YLKLGNAYKSHNDFPKAIECYEKSLIIARRAGD 819 678**********************99999887 PP == domain 18 score: 16.1 bits; conditional E-value: 2.2e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y ++ d +Ai++ye+ L +a++ +d+ FUN_000362-T1 826 AFFNLGIVYNSCSDLPKAIEYYEKSLNIAREAGDK 860 678****************************9997 PP == domain 19 score: 11.5 bits; conditional E-value: 0.00066 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+++y++ + +A ++ye+ L +a++ +dr+ FUN_000362-T1 866 AYLNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRA 901 789******************************985 PP == domain 20 score: 18.4 bits; conditional E-value: 3.8e-06 TPR_7 3 saLariyrklGdydeAirlyerlLalakdped 34 ++L+++y +Gd+ +Ai++ye+ L +a + +d FUN_000362-T1 908 YNLGSVYLCRGDRSKAIECYEKSLHIAGEAGD 939 59********************9999877766 PP == domain 21 score: 8.1 bits; conditional E-value: 0.0079 TPR_7 5 LariyrklGdydeAirlyerlLalakdpedr 35 L+ +y+++ d +Ai++y + L +a++ +dr FUN_000362-T1 950 LGVVYESRCDLTNAIDCYVKSLNIAREAGDR 980 99**************************998 PP == domain 22 score: 13.8 bits; conditional E-value: 0.00011 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ L+ +y +l d+++Ai+++e+ L +a++ +dr FUN_000362-T1 1117 AYFHLGAVYLSLSDFRKAIECHEKGLNIAREVGDR 1151 6789***************************9998 PP == domain 23 score: 16.4 bits; conditional E-value: 1.7e-05 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpedre 36 L+ +y+ + d+ +Ai++ye+ L++a++ +dr+ FUN_000362-T1 1160 HLGTVYHFQSDFPKAIECYEKSLDIAREAGDRA 1192 79****************************985 PP == domain 24 score: 17.1 bits; conditional E-value: 1e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdped 34 +L+ +y +++d +Ai++ye+ L +a++++d FUN_000362-T1 1199 FNLGTVYKSRNDLPKAIEFYEKSLNIAREEGD 1230 69**************************9987 PP == domain 25 score: 19.8 bits; conditional E-value: 1.4e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +y ++ d+++Ai++ye+ L +a + +dr+ FUN_000362-T1 1237 AYLNLGLVYDSQSDFRNAIECYEKSLLIATKAGDRA 1272 789**************************9999985 PP == domain 26 score: 14.9 bits; conditional E-value: 5.2e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedre 36 +L+ +y +++d +A ++ye+ L ++++ +dr+ FUN_000362-T1 1279 FNLGTVYKSRNDLPKAMEFYEKSLNISREAGDRA 1312 69****************************9985 PP == domain 27 score: 18.2 bits; conditional E-value: 4.4e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLala 29 a+++L+ iy ++ ++ +Ai++ye+ L +a FUN_000362-T1 1317 ACLNLGLIYDSQSNFSKAIECYEKSLNIA 1345 8***********************98876 PP == domain 28 score: 4.0 bits; conditional E-value: 0.16 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+ +L+ +y d+ +A +++e+ L +a++ +d FUN_000362-T1 1357 AYFSLGIVYKLHKDFAKAFECFEKSLNIAREAGD 1390 6789*************************99988 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.1 0.034 20 16 32 .. 32 48 .. 28 49 .. 0.86 2 ! 19.6 0.1 1.7e-06 0.00096 2 32 .. 58 88 .. 57 89 .. 0.95 3 ! 19.5 0.0 1.8e-06 0.0011 2 32 .. 98 128 .. 97 129 .. 0.95 4 ? 6.5 0.1 0.028 16 2 32 .. 138 168 .. 137 169 .. 0.90 5 ! 9.7 0.1 0.0024 1.4 4 32 .. 180 208 .. 179 209 .. 0.93 6 ! 16.8 0.0 1.3e-05 0.0078 2 32 .. 218 248 .. 217 249 .. 0.94 7 ! 21.4 0.1 4.6e-07 0.00027 2 32 .. 258 288 .. 257 289 .. 0.95 8 ! 18.4 0.1 4.2e-06 0.0025 2 32 .. 298 328 .. 297 329 .. 0.94 9 ! 17.8 0.0 6.6e-06 0.0038 2 32 .. 338 368 .. 337 369 .. 0.94 10 ! 9.6 0.0 0.0028 1.6 2 32 .. 378 408 .. 377 409 .. 0.93 11 ! 11.1 0.0 0.00091 0.53 2 29 .. 418 445 .. 417 446 .. 0.92 12 ! 11.0 0.0 0.00098 0.57 2 30 .. 458 486 .. 457 489 .. 0.93 13 ! 19.8 0.1 1.5e-06 0.00087 2 32 .. 498 528 .. 497 529 .. 0.95 14 ! 13.3 0.0 0.00018 0.11 2 32 .. 538 568 .. 537 569 .. 0.94 15 ! 9.2 0.0 0.0037 2.2 2 32 .. 578 608 .. 577 609 .. 0.93 16 ! 17.2 0.1 9.6e-06 0.0056 2 30 .. 745 773 .. 744 775 .. 0.95 17 ! 14.5 0.1 7.4e-05 0.043 2 28 .. 785 811 .. 784 815 .. 0.94 18 ! 12.4 0.0 0.00033 0.19 3 32 .. 826 855 .. 824 856 .. 0.93 19 ! 10.3 0.1 0.0017 0.96 3 32 .. 866 895 .. 864 896 .. 0.94 20 ! 15.3 0.1 4.2e-05 0.024 2 28 .. 905 931 .. 904 936 .. 0.92 21 ! 10.0 0.0 0.002 1.2 2 32 .. 945 975 .. 944 976 .. 0.94 22 ? 0.4 0.0 2.4 1.4e+03 3 18 .. 993 1008 .. 992 1017 .. 0.90 23 ! 16.1 0.0 2.2e-05 0.013 1 32 [. 1115 1146 .. 1115 1148 .. 0.95 24 ! 13.7 0.0 0.00013 0.078 3 32 .. 1157 1186 .. 1155 1187 .. 0.92 25 ! 17.5 0.0 8.2e-06 0.0047 4 33 .. 1198 1227 .. 1196 1228 .. 0.94 26 ! 21.6 0.1 3.9e-07 0.00022 2 31 .. 1236 1265 .. 1235 1267 .. 0.93 27 ! 16.5 0.0 1.6e-05 0.0094 4 32 .. 1278 1306 .. 1276 1307 .. 0.94 28 ! 21.5 0.2 4.2e-07 0.00024 2 30 .. 1316 1344 .. 1315 1345 .. 0.94 29 ! 14.1 0.1 9.7e-05 0.057 2 32 .. 1356 1386 .. 1355 1387 .. 0.95 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.034 TPR_8 16 dyeeAkeyyekaleldp 32 d+ +++e+yek+l+++ FUN_000362-T1 32 DFSKSIECYEKSLKIAS 48 8999**********985 PP == domain 2 score: 19.6 bits; conditional E-value: 1.7e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y ++ d+ +A+e+ye++l++++ FUN_000362-T1 58 DAYLNLGRVYDSQSDFPKAIECYEESLKIAK 88 69**************************986 PP == domain 3 score: 19.5 bits; conditional E-value: 1.8e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlGl+ ++ d+ +++e+yek+l+++ FUN_000362-T1 98 KAYFNLGLVFDSQSDFSKSIECYEKSLKIAS 128 79**************************985 PP == domain 4 score: 6.5 bits; conditional E-value: 0.028 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nl ++y+++ d+++ +++yek+l++++ FUN_000362-T1 138 DAYLNLRRVYESQSDFAKPIQFYEKSLKIAR 168 578888899*******************987 PP == domain 5 score: 9.7 bits; conditional E-value: 0.0024 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldp 32 y++ G++y + ++ +A+++y+k+l++++ FUN_000362-T1 180 YLKVGRVYDSESNFPKAIKFYKKSLKIAK 208 7889**********************986 PP == domain 6 score: 16.8 bits; conditional E-value: 1.3e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ lG++y +l ++ +++e+yek+l++++ FUN_000362-T1 218 KAYLSLGRVYDTLSNFPKSIECYEKSLTIAK 248 89**************************986 PP == domain 7 score: 21.4 bits; conditional E-value: 4.6e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlGl+y ++ d+ +A+e+yek+l++++ FUN_000362-T1 258 DAYLNLGLVYDSQSDFPKAIECYEKSLKIAR 288 69**************************987 PP == domain 8 score: 18.4 bits; conditional E-value: 4.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlGl+y ++g + +++e+yek+l+++ FUN_000362-T1 298 KAYLNLGLVYGSQGIFGKSIECYEKSLRIAS 328 79*************************9985 PP == domain 9 score: 17.8 bits; conditional E-value: 6.6e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +a +nlGl+y ++ d+ +A+e+yek+l++++ FUN_000362-T1 338 DAFFNLGLVYDSQSDFPKAVECYEKSLKIAK 368 689*************************986 PP == domain 10 score: 9.6 bits; conditional E-value: 0.0028 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y + d+ +A+e+ ek+l +++ FUN_000362-T1 378 DAYLNLGCLYNSESDFPKAIECDEKSLNIAR 408 69**********************9999986 PP == domain 11 score: 11.1 bits; conditional E-value: 0.00091 TPR_8 2 eayynlGliylklgdyeeAkeyyekale 29 +ay+nlGl+y ++ ++ +++e+ye+ l+ FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLK 445 79**********************8666 PP == domain 12 score: 11.0 bits; conditional E-value: 0.00098 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay+nlG +y ++ ++ +++e++ek+l+ FUN_000362-T1 458 KAYFNLGFVYNSQSEFPKSIECFEKSLKT 486 79************************985 PP == domain 13 score: 19.8 bits; conditional E-value: 1.5e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+nlG++y ++ d+ +A+e+ye++l++++ FUN_000362-T1 498 DAYLNLGRVYFSQSDFCKAIECYEESLKIAR 528 69**************************987 PP == domain 14 score: 13.3 bits; conditional E-value: 0.00018 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+n Gl ++gd+ A+e+yek+l+++ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKSLKIAS 568 69**************************985 PP == domain 15 score: 9.2 bits; conditional E-value: 0.0037 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++y+nlG++y ++ d+ + e++e +l++++ FUN_000362-T1 578 KVYLNLGHVYYSQSDFRKETECCENSLSIAK 608 68*************************9986 PP == domain 16 score: 17.2 bits; conditional E-value: 9.6e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 + y+nlG +y + ++ +A+++yekal + FUN_000362-T1 745 RFYFNLGVVYYSRSEFRKAIKCYEKALNI 773 78************************986 PP == domain 17 score: 14.5 bits; conditional E-value: 7.4e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekal 28 ++y++lG++y++ +d+ +A+e+yek+l FUN_000362-T1 785 DSYLKLGNAYKSHNDFPKAIECYEKSL 811 68***********************87 PP == domain 18 score: 12.4 bits; conditional E-value: 0.00033 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 a +nlG +y + d+ +A+eyyek+l +++ FUN_000362-T1 826 AFFNLGIVYNSCSDLPKAIEYYEKSLNIAR 855 789***********************9987 PP == domain 19 score: 10.3 bits; conditional E-value: 0.0017 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay+nlG++y++ + +A ++yek+l +++ FUN_000362-T1 866 AYLNLGNAYMSHDESPKAFNCYEKSLNIAR 895 9*************************9987 PP == domain 20 score: 15.3 bits; conditional E-value: 4.2e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekal 28 +a ynlG++yl gd +A+e+yek+l FUN_000362-T1 905 KANYNLGSVYLCRGDRSKAIECYEKSL 931 689**********************98 PP == domain 21 score: 10.0 bits; conditional E-value: 0.002 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ lG +y++ d+ +A+ +y k+l +++ FUN_000362-T1 945 KAYFTLGVVYESRCDLTNAIDCYVKSLNIAR 975 79*************************9986 PP == domain 22 score: 0.4 bits; conditional E-value: 2.4 TPR_8 3 ayynlGliylklgdye 18 +y+ lG++++ +g+ e FUN_000362-T1 993 SYLALGDVLKATGNRE 1008 799**********987 PP == domain 23 score: 16.1 bits; conditional E-value: 2.2e-05 TPR_8 1 aeayynlGliylklgdyeeAkeyyekaleldp 32 aeay++lG +yl+l d+ +A+e+ ek l +++ FUN_000362-T1 1115 AEAYFHLGAVYLSLSDFRKAIECHEKGLNIAR 1146 79*************************99987 PP == domain 24 score: 13.7 bits; conditional E-value: 0.00013 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 a ++lG +y+ + d+ +A+e+yek+l++++ FUN_000362-T1 1157 ASFHLGTVYHFQSDFPKAIECYEKSLDIAR 1186 6689***********************987 PP == domain 25 score: 17.5 bits; conditional E-value: 8.2e-06 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldpd 33 y+nlG +y++ +d+ +A+e+yek+l ++++ FUN_000362-T1 1198 YFNLGTVYKSRNDLPKAIEFYEKSLNIARE 1227 9*************************9875 PP == domain 26 score: 21.6 bits; conditional E-value: 3.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay+nlGl+y ++ d+ +A+e+yek+l ++ FUN_000362-T1 1236 KAYLNLGLVYDSQSDFRNAIECYEKSLLIA 1265 79***********************99775 PP == domain 27 score: 16.5 bits; conditional E-value: 1.6e-05 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldp 32 y+nlG +y++ +d+ +A+e+yek+l +++ FUN_000362-T1 1278 YFNLGTVYKSRNDLPKAMEFYEKSLNISR 1306 9************************9986 PP == domain 28 score: 21.5 bits; conditional E-value: 4.2e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +a++nlGliy ++ ++ +A+e+yek+l + FUN_000362-T1 1316 KACLNLGLIYDSQSNFSKAIECYEKSLNI 1344 69************************987 PP == domain 29 score: 14.1 bits; conditional E-value: 9.7e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay+ lG +y+ +d+++A e++ek+l +++ FUN_000362-T1 1356 KAYFSLGIVYKLHKDFAKAFECFEKSLNIAR 1386 79*************************9987 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 1.7e-05 0.0098 3 35 .. 58 90 .. 57 90 .. 0.94 2 ? 1.0 0.0 1.2 6.9e+02 7 32 .. 102 127 .. 98 129 .. 0.88 3 ? 0.0 0.0 2.4 1.4e+03 5 35 .. 140 170 .. 138 170 .. 0.79 4 ? 1.9 0.0 0.61 3.6e+02 8 34 .. 183 209 .. 180 210 .. 0.84 5 ! 7.7 0.0 0.0091 5.3 4 35 .. 219 250 .. 217 250 .. 0.94 6 ! 15.2 0.0 3.9e-05 0.022 3 35 .. 258 290 .. 257 290 .. 0.95 7 ? 6.1 0.0 0.029 17 4 32 .. 299 327 .. 298 329 .. 0.93 8 ! 11.6 0.0 0.00051 0.3 7 35 .. 342 370 .. 342 370 .. 0.96 9 ! 8.3 0.0 0.0059 3.4 3 35 .. 378 410 .. 377 410 .. 0.94 10 ! 14.1 0.0 8.5e-05 0.049 4 34 .. 419 449 .. 418 450 .. 0.93 11 ? 4.9 0.0 0.07 40 7 31 .. 462 486 .. 459 489 .. 0.93 12 ! 14.2 0.0 8.1e-05 0.047 3 35 .. 498 530 .. 497 533 .. 0.95 13 ! 11.1 0.0 0.00077 0.45 3 32 .. 538 567 .. 537 569 .. 0.93 14 ! 8.0 0.0 0.0071 4.1 5 34 .. 580 609 .. 578 610 .. 0.94 15 ! 11.4 0.0 0.0006 0.35 7 32 .. 749 774 .. 748 777 .. 0.92 16 ! 13.8 0.0 0.00011 0.061 3 35 .. 785 817 .. 784 817 .. 0.95 17 ! 10.0 0.0 0.0017 0.96 7 35 .. 829 857 .. 829 857 .. 0.96 18 ! 10.9 0.0 0.00089 0.52 4 35 .. 866 897 .. 864 897 .. 0.95 19 ! 9.4 0.0 0.0025 1.5 7 32 .. 909 934 .. 908 937 .. 0.93 20 ? -1.8 0.0 8.9 5.2e+03 8 34 .. 950 976 .. 949 977 .. 0.89 21 ? 6.2 0.0 0.026 15 7 35 .. 1120 1148 .. 1115 1148 .. 0.81 22 ! 7.7 0.0 0.009 5.2 7 35 .. 1160 1188 .. 1160 1188 .. 0.95 23 ! 12.4 0.0 0.0003 0.18 7 34 .. 1200 1227 .. 1199 1228 .. 0.96 24 ! 10.0 0.1 0.0017 0.96 4 34 .. 1237 1267 .. 1236 1268 .. 0.92 25 ! 14.2 0.0 7.9e-05 0.046 7 35 .. 1280 1308 .. 1279 1308 .. 0.96 26 ! 8.8 0.0 0.0041 2.4 5 31 .. 1318 1344 .. 1316 1347 .. 0.92 27 ? 6.7 0.0 0.018 11 8 35 .. 1361 1388 .. 1357 1388 .. 0.94 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 1.7e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL++++ +q ++ A e +ee+l+i++++ FUN_000362-T1 58 DAYLNLGRVYDSQSDFPKAIECYEESLKIAKEA 90 5899*************************9985 PP == domain 2 score: 1.0 bits; conditional E-value: 1.2 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+ + +q ++ + e +e++l+i+ FUN_000362-T1 102 NLGLVFDSQSDFSKSIECYEKSLKIA 127 89999999999999999999999985 PP == domain 3 score: 0.0 bits; conditional E-value: 2.4 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + nL +++ +q +++ +++e++l+i++++ FUN_000362-T1 140 YLNLRRVYESQSDFAKPIQFYEKSLKIAREA 170 55666778888888888899*******9985 PP == domain 4 score: 1.9 bits; conditional E-value: 0.61 TPR_10 8 LanalraqgryeeAeelleealairer 34 ++++ + ++ A ++++++l+i+++ FUN_000362-T1 183 VGRVYDSESNFPKAIKFYKKSLKIAKK 209 5788888889999**********9998 PP == domain 5 score: 7.7 bits; conditional E-value: 0.0091 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L++++ + ++ + e +e++l+i++++ FUN_000362-T1 219 AYLSLGRVYDTLSNFPKSIECYEKSLTIAKEA 250 7899************************9985 PP == domain 6 score: 15.2 bits; conditional E-value: 3.9e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL+ ++ +q ++ A e +e++l+i++++ FUN_000362-T1 258 DAYLNLGLVYDSQSDFPKAIECYEKSLKIAREA 290 5899*************************9985 PP == domain 7 score: 6.1 bits; conditional E-value: 0.029 TPR_10 4 slnnLanalraqgryeeAeelleealair 32 ++ nL+ ++ +qg + + e +e++l+i+ FUN_000362-T1 299 AYLNLGLVYGSQGIFGKSIECYEKSLRIA 327 799***********************985 PP == domain 8 score: 11.6 bits; conditional E-value: 0.00051 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ ++ +q ++ A+e +e++l+i++++ FUN_000362-T1 342 NLGLVYDSQSDFPKAVECYEKSLKIAKEA 370 9************************9985 PP == domain 9 score: 8.3 bits; conditional E-value: 0.0059 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL++++ + ++ A e e++l i++++ FUN_000362-T1 378 DAYLNLGCLYNSESDFPKAIECDEKSLNIAREA 410 5899*************************9985 PP == domain 10 score: 14.1 bits; conditional E-value: 8.5e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+ ++++q ++ + e +ee+l+i ++ FUN_000362-T1 419 AYLNLGLVYFSQSNFPKSIECYEETLKIVRE 449 799************************9876 PP == domain 11 score: 4.9 bits; conditional E-value: 0.07 TPR_10 7 nLanalraqgryeeAeelleealai 31 nL+ ++ +q ++ + e +e++l++ FUN_000362-T1 462 NLGFVYNSQSEFPKSIECFEKSLKT 486 9*********************986 PP == domain 12 score: 14.2 bits; conditional E-value: 8.1e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ nL++++++q ++ A e +ee+l+i++++ FUN_000362-T1 498 DAYLNLGRVYFSQSDFCKAIECYEESLKIAREA 530 5899*************************9985 PP == domain 13 score: 11.1 bits; conditional E-value: 0.00077 TPR_10 3 sslnnLanalraqgryeeAeelleealair 32 +++ n + ++qg++ A e +e++l+i+ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKSLKIA 567 5899***********************985 PP == domain 14 score: 8.0 bits; conditional E-value: 0.0071 TPR_10 5 lnnLanalraqgryeeAeelleealairer 34 + nL+ ++++q ++ e +e +l i+++ FUN_000362-T1 580 YLNLGHVYYSQSDFRKETECCENSLSIAKE 609 88*************************998 PP == domain 15 score: 11.4 bits; conditional E-value: 0.0006 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+++++++ ++ A + +e+al i FUN_000362-T1 749 NLGVVYYSRSEFRKAIKCYEKALNIF 774 9**********************985 PP == domain 16 score: 13.8 bits; conditional E-value: 0.00011 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +s+ L+na+ + +++ A e +e++l i++r+ FUN_000362-T1 785 DSYLKLGNAYKSHNDFPKAIECYEKSLIIARRA 817 58999**************************96 PP == domain 17 score: 10.0 bits; conditional E-value: 0.0017 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL+ ++ ++ ++ A e++e++l i++++ FUN_000362-T1 829 NLGIVYNSCSDLPKAIEYYEKSLNIAREA 857 9************************9985 PP == domain 18 score: 10.9 bits; conditional E-value: 0.00089 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+ + + A + +e++l i++++ FUN_000362-T1 866 AYLNLGNAYMSHDESPKAFNCYEKSLNIAREA 897 899*************************9985 PP == domain 19 score: 9.4 bits; conditional E-value: 0.0025 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+ ++ +g++ A e +e++l i+ FUN_000362-T1 909 NLGSVYLCRGDRSKAIECYEKSLHIA 934 9**********************986 PP == domain 20 score: -1.8 bits; conditional E-value: 8.9 TPR_10 8 LanalraqgryeeAeelleealairer 34 L++++ ++ +++ A + + ++l i+++ FUN_000362-T1 950 LGVVYESRCDLTNAIDCYVKSLNIARE 976 8999999999999*********99998 PP == domain 21 score: 6.2 bits; conditional E-value: 0.026 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 +L++++ ++ ++ A e +e+ l i+++v FUN_000362-T1 1120 HLGAVYLSLSDFRKAIECHEKGLNIAREV 1148 78999999999999999999999998886 PP == domain 22 score: 7.7 bits; conditional E-value: 0.009 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 +L++++ q ++ A e +e++l+i++++ FUN_000362-T1 1160 HLGTVYHFQSDFPKAIECYEKSLDIAREA 1188 69***********************9985 PP == domain 23 score: 12.4 bits; conditional E-value: 0.0003 TPR_10 7 nLanalraqgryeeAeelleealairer 34 nL++++ +++++ A e++e++l i+++ FUN_000362-T1 1200 NLGTVYKSRNDLPKAIEFYEKSLNIARE 1227 9************************987 PP == domain 24 score: 10.0 bits; conditional E-value: 0.0017 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+ ++ +q ++ A e +e++l i+ + FUN_000362-T1 1237 AYLNLGLVYDSQSDFRNAIECYEKSLLIATK 1267 799***********************98765 PP == domain 25 score: 14.2 bits; conditional E-value: 7.9e-05 TPR_10 7 nLanalraqgryeeAeelleealairerv 35 nL++++ +++++ A+e++e++l i +++ FUN_000362-T1 1280 NLGTVYKSRNDLPKAMEFYEKSLNISREA 1308 9************************9985 PP == domain 26 score: 8.8 bits; conditional E-value: 0.0041 TPR_10 5 lnnLanalraqgryeeAeelleealai 31 + nL+ ++ +q ++ A e +e++l i FUN_000362-T1 1318 CLNLGLIYDSQSNFSKAIECYEKSLNI 1344 67**********************987 PP == domain 27 score: 6.7 bits; conditional E-value: 0.018 TPR_10 8 LanalraqgryeeAeelleealairerv 35 L+ ++ ++++ A e +e++l i++++ FUN_000362-T1 1361 LGIVYKLHKDFAKAFECFEKSLNIAREA 1388 99**********************9985 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.1 1.1e-07 6.1e-05 85 180 .. 28 122 .. 22 125 .. 0.89 2 ! 23.4 0.1 8.4e-08 4.9e-05 67 180 .. 89 202 .. 84 212 .. 0.90 3 ! 16.4 0.0 1.2e-05 0.0067 83 180 .. 225 322 .. 204 330 .. 0.77 4 ! 27.9 0.0 3.5e-09 2e-06 44 177 .. 266 399 .. 256 410 .. 0.93 5 ! 25.3 0.0 2.3e-08 1.4e-05 45 182 .. 347 484 .. 333 491 .. 0.93 6 ! 27.9 0.0 3.7e-09 2.1e-06 38 180 .. 380 522 .. 377 532 .. 0.92 7 ! 23.5 0.1 8e-08 4.6e-05 49 180 .. 431 562 .. 427 573 .. 0.73 8 ! 17.6 0.1 5e-06 0.0029 45 173 .. 467 595 .. 458 606 .. 0.78 9 ! 25.2 0.1 2.4e-08 1.4e-05 115 180 .. 745 809 .. 733 820 .. 0.69 10 ! 25.1 1.5 2.5e-08 1.5e-05 50 179 .. 839 968 .. 824 1008 .. 0.87 11 ! 29.7 0.1 1e-09 6e-07 52 180 .. 1091 1220 .. 1085 1228 .. 0.94 12 ! 37.9 0.9 3.2e-12 1.9e-09 43 180 .. 1203 1340 .. 1198 1359 .. 0.95 13 ? 2.6 0.1 0.19 1.1e+02 43 72 .. 1363 1392 .. 1355 1405 .. 0.80 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 1.1e-07 SNAP 85 ykksdpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 +ksd ++++e++ek+ +i e g + ++ + +++ +y+++ +d+ kAie+Ye++ ++ ++ + ++ k++ ++ + ++ +++k+ie yek FUN_000362-T1 28 ASKSDFSKSIECYEKSLKIASEGGDRATEGDAYLNLGRVYDSQ-SDFPKAIECYEESLKIAKEAGDRVRKGKAYFNLGLVFDSQSDFSKSIECYEK 122 4678899999999999999999999999999999999999999.9999999999999999999999999999999999999999999999999997 PP == domain 2 score: 23.4 bits; conditional E-value: 8.4e-08 SNAP 67 klkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkv 161 +++++ ++ay++ ++ ++ d ++++e++ek+ +i e g + ++ + ++ +ye++ +d+ k i+ Ye++ ++ ++ + al +lkv FUN_000362-T1 89 EAGDRVRKGKAYFNLGLVFDSQsDFSKSIECYEKSLKIASEGGDWATEGDAYLNLRRVYESQ-SDFAKPIQFYEKSLKIAREAGDRALEGVGYLKV 183 56666667788888888887665899************************************.********************************* PP SNAP 162 AdlsaelekyekAieiyek 180 ++ ++ +++kAi+ y+k FUN_000362-T1 184 GRVYDSESNFPKAIKFYKK 202 *****************96 PP == domain 3 score: 16.4 bits; conditional E-value: 1.2e-05 SNAP 83 kcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAiei 177 ++y + + +++e++ek+ +i e+g + ++ + +++ +y+++ +d+ kAie+Ye++ ++ ++ + + k++l++ ++ +++ + k+ie FUN_000362-T1 225 RVYDTLsNFPKSIECYEKSLTIAKEAGDRVTEGDAYLNLGLVYDSQ-SDFPKAIECYEKSLKIAREAGDRVREGKAYLNLGLVYGSQGIFGKSIEC 319 5555442556788888888888888888888888888888888888.8888888888888888888888888888888888888888888888888 PP SNAP 178 yek 180 yek FUN_000362-T1 320 YEK 322 886 PP == domain 4 score: 27.9 bits; conditional E-value: 3.5e-09 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 y + ++ +A e+++k ++ ++++++ ++ay++ +y ++ +++e++ek+ i e g + ++ ++++ +y+++ +d+ kA+e+Y FUN_000362-T1 266 VYDSQSDFPKAIECYEKSLKIAREAGDRVREGKAYLNLGLVYGSQgIFGKSIECYEKSLRIASEGGDRATEGDAFFNLGLVYDSQ-SDFPKAVECY 360 677788999*********************************9984567************************************.********** PP SNAP 139 eqAadlyeqeeaealankcllkvAdlsaelekyekAiei 177 e++ ++ ++ + +l ++l++ l+ ++ +++kAie FUN_000362-T1 361 EKSLKIAKEAGDRTLEGDAYLNLGCLYNSESDFPKAIEC 399 *************************************96 PP == domain 5 score: 25.3 bits; conditional E-value: 2.3e-08 SNAP 45 yklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYe 139 y + ++ +A e+++k ++ +++++++ ++ay++ y+++ d +A+e+ ek+ +i e+g r +k + +++ +y ++ +++ k+ie+Ye FUN_000362-T1 347 YDSQSDFPKAVECYEKSLKIAKEAGDRTLEGDAYLNLGCLYNSEsDFPKAIECDEKSLNIAREAGDPVREGKAYLNLGLVYFSQ-SNFPKSIECYE 441 66788999****************************999998875778************************************.*********** PP SNAP 140 qAadlyeqeeaealankcllkvAdlsaelekyekAieiyekva 182 + ++ ++ + + k++ ++ ++ ++ +++k+ie +ek FUN_000362-T1 442 ETLKIVREAGDRVREGKAYFNLGFVYNSQSEFPKSIECFEKSL 484 ****************************************865 PP == domain 6 score: 27.9 bits; conditional E-value: 3.7e-09 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + + +y + ++ +A e+ +k ++ ++++++ ++ay++ +y ++ + +++e++e++ +i e+g r +k +++++ +y+++ +++ FUN_000362-T1 380 YLNLGCLYNSESDFPKAIECDEKSLNIAREAGDPVREGKAYLNLGLVYFSQsNFPKSIECYEETLKIVREAGDRVREGKAYFNLGFVYNSQ-SEFP 474 555566788889999999999999999999*************999988764778************************************.**** PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 k+ie++e++ + ++ + a+ ++l++ ++ ++ ++ kAie ye+ FUN_000362-T1 475 KSIECFEKSLKTASEGRDRATEGDAYLNLGRVYFSQSDFCKAIECYEE 522 ************99999*****************************97 PP == domain 7 score: 23.5 bits; conditional E-value: 8e-08 SNAP 49 kkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAad 143 ++ ++ e+++++ ++ ++++++ ++ay++ +y+++ + +++e++ek+ ++ e + ++ + +++ +y ++ +d+ kAie+Ye++ + FUN_000362-T1 431 SNFPKSIECYEETLKIVREAGDRVREGKAYFNLGFVYNSQsEFPKSIECFEKSLKTASEGRDRATEGDAYLNLGRVYFSQ-SDFCKAIECYEESLK 525 56667777888888888888888888888888777777663455888888888887665555555677777888888888.888888888888888 PP SNAP 144 lyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + ++ + l ++l+v + ++++++ Aie yek FUN_000362-T1 526 IAREAGNRDLEGDAYLNVGLFFYSQGDFPIAIECYEK 562 8888888888888888888888888888888888876 PP == domain 8 score: 17.6 bits; conditional E-value: 5e-06 SNAP 45 yklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYe 139 y + ++ ++ e+f+k ++ ++ ++ ++ay++ ++y ++ d +A+e++e++ +i e+g+ + ++ + +++ + ++ +d+ Aie+Ye FUN_000362-T1 467 YNSQSEFPKSIECFEKSLKTASEGRDRATEGDAYLNLGRVYFSQsDFCKAIECYEESLKIAREAGNRDLEGDAYLNVGLFFYSQ-GDFPIAIECYE 561 666777888888888888888888888888889998888887664677899999999999999999999999999999888888.89999999999 PP SNAP 140 qAadlyeqeeaealankcllkvAdlsaelekyek 173 ++ ++ ++ a+ k++l++ +++ ++ ++ k FUN_000362-T1 562 KSLKIASEGVDWATEGKVYLNLGHVYYSQSDFRK 595 8888776666777777777777777776666666 PP == domain 9 score: 25.2 bits; conditional E-value: 2.4e-08 SNAP 115 klkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 +++++++ +y + ++++kAi++Ye+A +++++ + +al +lk+ + + ++++++kAie yek FUN_000362-T1 745 RFYFNLGVVYYSR-SEFRKAIKCYEKALNIFTEVGEQALEGDSYLKLGNAYKSHNDFPKAIECYEK 809 5666666666666.6777777777777777777777777777777777777777777777777765 PP == domain 10 score: 25.1 bits; conditional E-value: 2.5e-08 SNAP 50 kwkeAgeaflkaAecqeklkekdeaanayveAakcykksdpe.eAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadl 144 ++ +A e ++k ++ +++++k + +nay++ ++y + d + +A +++ek+ +i e+g + +k + +++ +y +d +kAie+Ye++ ++ FUN_000362-T1 839 DLPKAIEYYEKSLNIAREAGDKAKEGNAYLNLGNAYMSHDESpKAFNCYEKSLNIAREAGDRATEGKANYNLGSVYLCR-GDRSKAIECYEKSLHI 933 5678999*****************************9997666**********************************99.************9998 PP SNAP 145 yeqeeaealankcllkvAdlsaelekyekAieiye 179 + + ++ k++ + ++ + ++++Ai+ y FUN_000362-T1 934 AGEAGDGTTEGKAYFTLGVVYESRCDLTNAIDCYV 968 88888888888888888888888888888888775 PP == domain 11 score: 29.7 bits; conditional E-value: 1e-09 SNAP 52 keAgeaflkaAecqek.lkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAad 143 ++Ag+++ e++e+ ++++ a+ay+ +y + d +A+e+ ek +i e g ++ +k +++++ +y + +d+ kAie+Ye++ d FUN_000362-T1 1091 DSAGSVWTTQIETEEDyAGDRATKAEAYFHLGAVYLSLsDFRKAIECHEKGLNIAREVGDRTTEGKASFHLGTVYHFQ-SDFPKAIECYEKSLD 1183 789*************99999999999999988887654999************************************.*************** PP SNAP 144 lyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + ++ + a+ + + ++ ++ + ++++kAie yek FUN_000362-T1 1184 IAREAGDRATEGSGYFNLGTVYKSRNDLPKAIEFYEK 1220 ************************************7 PP == domain 12 score: 37.9 bits; conditional E-value: 3.2e-12 SNAP 43 nayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAi 135 + yk ++++ +A e ++k ++ ++ ++ ++ay++ +y ++ d +A+e++ek+ i t++g ++ +++++ +y++ +dl kA+ FUN_000362-T1 1203 TVYKSRNDLPKAIEFYEKSLNIAREEGDWAREGKAYLNLGLVYDSQsDFRNAIECYEKSLLIATKAGDRAAEGSGYFNLGTVYKSR-NDLPKAM 1295 68*****************************************9875889******************999999************.******* PP SNAP 136 eaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e Ye++ ++ ++ + a+ k+ l++ ++ ++ +++kAie yek FUN_000362-T1 1296 EFYEKSLNISREAGDRATEGKACLNLGLIYDSQSNFSKAIECYEK 1340 ********************************************8 PP == domain 13 score: 2.6 bits; conditional E-value: 0.19 SNAP 43 nayklakkwkeAgeaflkaAecqeklkekd 72 ykl+k++ +A e+f+k ++ ++++++ FUN_000362-T1 1363 IVYKLHKDFAKAFECFEKSLNIAREAGDHA 1392 67****************999999887765 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 2.1e-08 1.2e-05 10 169 .. 66 225 .. 57 227 .. 0.95 2 ! 17.0 0.0 6.9e-06 0.004 25 156 .. 241 371 .. 225 383 .. 0.84 3 ! 26.3 0.0 1e-08 5.8e-06 10 158 .. 386 534 .. 381 543 .. 0.93 4 ! 27.0 0.0 6.2e-09 3.6e-06 9 180 .. 465 636 .. 463 651 .. 0.89 5 ! 8.6 0.0 0.0023 1.4 86 155 .. 750 817 .. 728 856 .. 0.71 6 ! 20.4 0.0 6.2e-07 0.00036 10 177 .. 833 1000 .. 829 1006 .. 0.81 7 ! 7.0 0.0 0.0073 4.3 80 157 .. 1115 1190 .. 1097 1196 .. 0.69 8 ! 35.3 0.0 1.8e-11 1.1e-08 9 158 .. 1163 1311 .. 1162 1319 .. 0.93 9 ! 19.7 0.0 1e-06 0.0006 43 175 .. 1278 1409 .. 1275 1411 .] 0.91 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 2.1e-08 TPR_MalT 10 lavsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyq 104 ++ sq ++++a+e +e L++ +e +r + a+++lG+++ q d++++ + +++ ++a + +++ a+l + +++ q ++++ ++ y+ FUN_000362-T1 66 VYDSQSDFPKAIECYEESLKIAKEAGDRVRkGKAYFNLGLVFDSQSDFSKSIECYEKSLKIASEGGDWATEGDAYLNLRRVYESQSDFAKPIQFYE 161 5668999*****************9999999**************************************99************************* PP TPR_MalT 105 qalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllar 169 + l+ a+e++ +al+ vg l +++++ + +A ++ ++++++++++ ++ + ++ay+ l r FUN_000362-T1 162 KSLKIAREAGDRALEGVGYL--KVGRVYDSESNFPKAIKFYKKSLKIAKKAgDRVREIKAYLSLGR 225 *************9999999..778*************************9788******998866 PP == domain 2 score: 17.0 bits; conditional E-value: 6.9e-06 TPR_MalT 25 reALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealp 119 ++ L++ +e d + + a+l+lG+++ q d+ +A + +++ ++ar+a++ + a+l ++ ++ qG + + +e y++ l+ a e + +a++ FUN_000362-T1 241 EKSLTIAKEAgDRVTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKIAREAGDRVREGKAYLNLGLVYGSQGIFGKSIECYEKSLRIASEGGDRATE 336 55555555542345568899*************************************************************************877 PP TPR_MalT 120 lvgfllvgladLlyEwndLeeAeqhlqqgiqlgrqle 156 +f l+ ++ + d+ +A ++ +++++++++++ FUN_000362-T1 337 GDAFF--NLGLVYDSQSDFPKAVECYEKSLKIAKEAG 371 66666..999**********************99973 PP == domain 3 score: 26.3 bits; conditional E-value: 1e-08 TPR_MalT 10 lavsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyq 104 l+ s+ ++++a+e ++ L++ +e ++r + a+l+lG++++ q ++ ++ + ++e+ ++ r+a++ + a+ ++ ++ q ++ + +e ++ FUN_000362-T1 386 LYNSESDFPKAIECDEKSLNIAREAGDPVReGKAYLNLGLVYFSQSNFPKSIECYEETLKIVREAGDRVREGKAYFNLGFVYNSQSEFPKSIECFE 481 56778899**************************************************************************************** PP TPR_MalT 105 qalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epa 158 + l+ a e + +a + g ++ l++++ + d+ +A ++ +++++++r++ +++ FUN_000362-T1 482 KSLKTASEGRDRA--TEGDAYLNLGRVYFSQSDFCKAIECYEESLKIAREAgNRD 534 ********99996..7789999***************************983445 PP == domain 4 score: 27.0 bits; conditional E-value: 6.2e-09 TPR_MalT 9 llavsqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaety 103 +++ sq e+++++e ++ L++ +e d ++ + a+l+lG++++ q d+++A + ++e ++ar+a++ + a+l + qG++ A+e y FUN_000362-T1 465 FVYNSQSEFPKSIECFEKSLKTASEgRDRATEGDAYLNLGRVYFSQSDFCKAIECYEESLKIAREAGNRDLEGDAYLNVGLFFYSQGDFPIAIECY 560 67788999999999999999887662566777**************************************9999********************** PP TPR_MalT 104 qqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeA 180 ++ l+ a e a + g ++ l++++y + d+ + ++++ ++ +++++ ++a +++ + +l++ a G+ + A FUN_000362-T1 561 EKSLKIASEGVDWA--TEGKVYLNLGHVYYSQSDFRKETECCENSLSIAKEAgDQAGVTRVNEFLLDSYTALGNSSKA 636 *******9988775..67788889***************************956677778999999999999987765 PP == domain 5 score: 8.6 bits; conditional E-value: 0.0023 TPR_MalT 86 qaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 ++ ++ + ++++A++ y++al +e +++a l g + l++ + nd+ +A ++ ++++ ++r++ FUN_000362-T1 750 LGVVYYSRSEFRKAIKCYEKALNIFTEVGEQA--LEGDSYLKLGNAYKSHNDFPKAIECYEKSLIIARRA 817 66677777778888888888888888887775..566667788888888888888888888887777775 PP == domain 6 score: 20.4 bits; conditional E-value: 6.2e-07 TPR_MalT 10 lavsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaet 102 ++ s+ + ++a+e+ ++ L++ +e a+ + a+l+lG a++ + +A + +++ +ar+a++ a + ++ ++ +G+ +A+e FUN_000362-T1 833 VYNSCSDLPKAIEYYEKSLNIAREAGDKAKeGNAYLNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRATEGKANYNLGSVYLCRGDRSKAIEC 926 5667888899999999999999888666666999999999999999999999999999999999999888888999999999999999999999 PP TPR_MalT 103 yqqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGel 177 y++ l+ a+e++ + g ++ l+ ++ + dL++A + ++++++r++ ++ + +a++ l la G++ FUN_000362-T1 927 YEKSLHIAGEAGDGT--TEGKAYFTLGVVYESRCDLTNAIDCYVKSLNIAREAgDRTGVNRANQYLGVSYLALGDV 1000 999999999998885..56777778999999999999999999999999999844455555777777777777766 PP == domain 7 score: 7.0 bits; conditional E-value: 0.0073 TPR_MalT 80 llallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrqlep 157 + a+ ++++++ ++++A+e +++l a+e + + ++ + l+ +++ + d+ +A ++ +++++++r+++ FUN_000362-T1 1115 AEAYFHLGAVYLSLSDFRKAIECHEKGLNIAREVGDRTTEGKASF--HLGTVYHFQSDFPKAIECYEKSLDIAREAGD 1190 566777777777777777777777777777777777765544443..4577777777777777777777777777644 PP == domain 8 score: 35.3 bits; conditional E-value: 1.8e-11 TPR_MalT 9 llavsqgeaeeaeelAreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAae 101 +++ +q ++++a+e ++ L++ +e d ++ ++ +++lG+++ ++dl +A + +++ +ar+++++ + a+l ++ ++ q ++++A+e FUN_000362-T1 1163 TVYHFQSDFPKAIECYEKSLDIAREAgDRATEGSGYFNLGTVYKSRNDLPKAIEFYEKSLNIAREEGDWAREGKAYLNLGLVYDSQSDFRNAIE 1256 57788999999999999***9999863567779999********************************************************** PP TPR_MalT 102 tyqqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrqlepa 158 y++ l a++++ +a++ +g l+ ++ +ndL +A ++ +++++++r+++ + FUN_000362-T1 1257 CYEKSLLIATKAGDRAAEGSGYF--NLGTVYKSRNDLPKAMEFYEKSLNISREAGDR 1311 ***************99999977..89*************************98554 PP == domain 9 score: 19.7 bits; conditional E-value: 1e-06 TPR_MalT 43 tlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwn 136 +++lG+++ ++dl +A + +++ ++r+a++ a l ++ ++ q + +A+e y++ l a e++ +a + g ++ +l+ ++ FUN_000362-T1 1278 YFNLGTVYKSRNDLPKAMEFYEKSLNISREAGDRATEGKACLNLGLIYDSQSNFSKAIECYEKSLNIAWEAGDQA--TEGKAYFSLGIVYKLHK 1369 699******************************9999999********************************997..66788889********* PP TPR_MalT 137 dLeeAeqhlqqgiqlgrqlepaaale.ayvllarvalaqG 175 d+ +A ++ +++++++r+++ +a + a++ la+ l G FUN_000362-T1 1370 DFAKAFECFEKSLNIAREAGDHAGVSrANQYLANSYLVPG 1409 ******************9776666559999998877666 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0083 4.8 1 25 [. 58 82 .. 58 87 .. 0.92 2 ? 3.6 0.0 0.31 1.8e+02 2 26 .. 99 123 .. 98 127 .. 0.91 3 ? -0.4 0.0 5.8 3.3e+03 3 25 .. 180 202 .. 179 206 .. 0.86 4 ! 9.3 0.0 0.0047 2.8 1 26 [. 258 283 .. 258 287 .. 0.93 5 ? 1.6 0.0 1.3 7.6e+02 2 25 .. 299 322 .. 298 326 .. 0.91 6 ! 8.9 0.0 0.0063 3.6 1 26 [. 338 363 .. 338 367 .. 0.93 7 ? 0.7 0.0 2.7 1.6e+03 1 21 [. 378 398 .. 378 399 .. 0.88 8 ? 5.0 0.0 0.11 66 2 28 .. 419 445 .. 418 447 .. 0.92 9 ? 1.5 0.0 1.5 8.5e+02 2 27 .. 459 484 .. 458 487 .. 0.89 10 ? 5.3 0.0 0.092 53 1 25 [. 498 522 .. 498 526 .. 0.91 11 ? 5.7 0.0 0.065 38 1 26 [. 538 563 .. 538 567 .. 0.92 12 ? 6.2 0.0 0.045 26 3 28 .. 747 772 .. 746 775 .. 0.91 13 ! 9.0 0.0 0.0058 3.4 1 25 [. 785 809 .. 785 811 .. 0.94 14 ? 2.2 0.0 0.9 5.2e+02 2 25 .. 826 849 .. 825 853 .. 0.91 15 ? 1.7 0.0 1.3 7.3e+02 2 25 .. 866 889 .. 865 893 .. 0.90 16 ? 3.3 0.0 0.4 2.3e+02 2 25 .. 906 929 .. 905 932 .. 0.89 17 ? 0.4 0.0 3.2 1.8e+03 5 19 .. 989 1003 .. 986 1004 .. 0.86 18 ? 2.8 0.0 0.56 3.3e+02 1 21 [. 1116 1136 .. 1116 1137 .. 0.93 19 ? 2.4 0.0 0.78 4.5e+02 2 25 .. 1157 1180 .. 1156 1184 .. 0.91 20 ? 4.6 0.0 0.15 87 3 25 .. 1198 1220 .. 1197 1224 .. 0.92 21 ? 7.1 0.0 0.023 13 2 25 .. 1237 1260 .. 1236 1262 .. 0.95 22 ? 4.3 0.0 0.19 1.1e+02 3 25 .. 1278 1300 .. 1277 1304 .. 0.92 23 ? 3.5 0.0 0.33 1.9e+02 4 25 .. 1319 1340 .. 1317 1343 .. 0.92 24 ? 4.3 0.0 0.19 1.1e+02 2 25 .. 1357 1380 .. 1356 1384 .. 0.92 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0083 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l++ y + d+ +A++ +++ FUN_000362-T1 58 DAYLNLGRVYDSQSDFPKAIECYEE 82 8**********************97 PP == domain 2 score: 3.6 bits; conditional E-value: 0.31 TPR_6 2 AllklalsylelgdkdeAkaalqrl 26 A+++l+l + + d+ + ++ +++ FUN_000362-T1 99 AYFNLGLVFDSQSDFSKSIECYEKS 123 99********************985 PP == domain 3 score: -0.4 bits; conditional E-value: 5.8 TPR_6 3 llklalsylelgdkdeAkaalqr 25 +lk ++ y ++ +A++++++ FUN_000362-T1 180 YLKVGRVYDSESNFPKAIKFYKK 202 689999999977*********98 PP == domain 4 score: 9.3 bits; conditional E-value: 0.0047 TPR_6 1 dAllklalsylelgdkdeAkaalqrl 26 dA+l+l+l y + d+ +A++ +++ FUN_000362-T1 258 DAYLNLGLVYDSQSDFPKAIECYEKS 283 8**********************985 PP == domain 5 score: 1.6 bits; conditional E-value: 1.3 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+l+l+l y +g + + ++ +++ FUN_000362-T1 299 AYLNLGLVYGSQGIFGKSIECYEK 322 99***********99999999987 PP == domain 6 score: 8.9 bits; conditional E-value: 0.0063 TPR_6 1 dAllklalsylelgdkdeAkaalqrl 26 dA+++l+l y + d+ +A++ +++ FUN_000362-T1 338 DAFFNLGLVYDSQSDFPKAVECYEKS 363 8**********************985 PP == domain 7 score: 0.7 bits; conditional E-value: 2.7 TPR_6 1 dAllklalsylelgdkdeAka 21 dA+l+l+ +y d+ +A++ FUN_000362-T1 378 DAYLNLGCLYNSESDFPKAIE 398 8*********99779999986 PP == domain 8 score: 5.0 bits; conditional E-value: 0.11 TPR_6 2 AllklalsylelgdkdeAkaalqrlik 28 A+l+l+l y+ + ++ + ++ +++ +k FUN_000362-T1 419 AYLNLGLVYFSQSNFPKSIECYEETLK 445 99********************98765 PP == domain 9 score: 1.5 bits; conditional E-value: 1.5 TPR_6 2 AllklalsylelgdkdeAkaalqrli 27 A+++l+ y + ++ + ++ +++ + FUN_000362-T1 459 AYFNLGFVYNSQSEFPKSIECFEKSL 484 99*********99******9999855 PP == domain 10 score: 5.3 bits; conditional E-value: 0.092 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 dA+l+l++ y+ + d+ +A++ +++ FUN_000362-T1 498 DAYLNLGRVYFSQSDFCKAIECYEE 522 8***********99**9***99997 PP == domain 11 score: 5.7 bits; conditional E-value: 0.065 TPR_6 1 dAllklalsylelgdkdeAkaalqrl 26 dA+l+ +l ++ +gd+ A++ +++ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKS 563 89*********************985 PP == domain 12 score: 6.2 bits; conditional E-value: 0.045 TPR_6 3 llklalsylelgdkdeAkaalqrlik 28 +++l++ y+ ++ +A++ +++ ++ FUN_000362-T1 747 YFNLGVVYYSRSEFRKAIKCYEKALN 772 699*******99**********9887 PP == domain 13 score: 9.0 bits; conditional E-value: 0.0058 TPR_6 1 dAllklalsylelgdkdeAkaalqr 25 d++lkl+ +y+ +d+ +A++ +++ FUN_000362-T1 785 DSYLKLGNAYKSHNDFPKAIECYEK 809 789*********99*********97 PP == domain 14 score: 2.2 bits; conditional E-value: 0.9 TPR_6 2 Allklalsyle.lgdkdeAkaalqr 25 A+++l+ y d +A++++++ FUN_000362-T1 826 AFFNLGIVYNScS-DLPKAIEYYEK 849 89*********99.*********98 PP == domain 15 score: 1.7 bits; conditional E-value: 1.3 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+l+l+ +y+ ++ +A +++ FUN_000362-T1 866 AYLNLGNAYMSHDESPKAFNCYEK 889 89*********9999999999987 PP == domain 16 score: 3.3 bits; conditional E-value: 0.4 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A ++l+ yl gd+ +A++ +++ FUN_000362-T1 906 ANYNLGSVYLCRGDRSKAIECYEK 929 66999*9999888*********97 PP == domain 17 score: 0.4 bits; conditional E-value: 3.2 TPR_6 5 klalsylelgdkdeA 19 +l++syl+lgd +A FUN_000362-T1 989 YLGVSYLALGDVLKA 1003 79********98665 PP == domain 18 score: 2.8 bits; conditional E-value: 0.56 TPR_6 1 dAllklalsylelgdkdeAka 21 +A+++l+ yl l d+ +A++ FUN_000362-T1 1116 EAYFHLGAVYLSLSDFRKAIE 1136 79**********99*****97 PP == domain 19 score: 2.4 bits; conditional E-value: 0.78 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A ++l+ y + d+ +A++ +++ FUN_000362-T1 1157 ASFHLGTVYHFQSDFPKAIECYEK 1180 7899*******99*********98 PP == domain 20 score: 4.6 bits; conditional E-value: 0.15 TPR_6 3 llklalsylelgdkdeAkaalqr 25 +++l+ y+ +d +A++++++ FUN_000362-T1 1198 YFNLGTVYKSRNDLPKAIEFYEK 1220 699*******9**********98 PP == domain 21 score: 7.1 bits; conditional E-value: 0.023 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A+l+l+l y + d+ +A++ +++ FUN_000362-T1 1237 AYLNLGLVYDSQSDFRNAIECYEK 1260 99********************97 PP == domain 22 score: 4.3 bits; conditional E-value: 0.19 TPR_6 3 llklalsylelgdkdeAkaalqr 25 +++l+ y+ +d +A++++++ FUN_000362-T1 1278 YFNLGTVYKSRNDLPKAMEFYEK 1300 699*******9**********98 PP == domain 23 score: 3.5 bits; conditional E-value: 0.33 TPR_6 4 lklalsylelgdkdeAkaalqr 25 l+l+l+y + ++ +A++ +++ FUN_000362-T1 1319 LNLGLIYDSQSNFSKAIECYEK 1340 78******************98 PP == domain 24 score: 4.3 bits; conditional E-value: 0.19 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A++ l+ y+ +d+++A + +++ FUN_000362-T1 1357 AYFSLGIVYKLHKDFAKAFECFEK 1380 8999*******99*********98 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.2 1.1e+02 6 23 .. 29 46 .. 25 50 .. 0.86 2 ! 9.5 0.1 0.0018 1.1 1 26 [. 64 89 .. 64 111 .. 0.76 3 ? 3.9 0.0 0.1 60 4 23 .. 107 126 .. 104 129 .. 0.84 4 ? 2.3 0.0 0.33 1.9e+02 1 23 [. 184 206 .. 184 210 .. 0.86 5 ? 0.7 0.0 1.1 6.2e+02 7 23 .. 230 246 .. 218 250 .. 0.80 6 ? 2.6 0.3 0.26 1.5e+02 29 38 .. 258 267 .. 256 271 .. 0.89 7 ! 10.3 2.2 0.001 0.59 1 42 [] 264 311 .. 264 311 .. 0.86 8 ? 3.7 0.1 0.12 69 1 23 [. 304 326 .. 304 330 .. 0.90 9 ? 1.2 0.0 0.73 4.2e+02 29 38 .. 338 347 .. 335 351 .. 0.89 10 ? 7.0 0.0 0.011 6.6 1 23 [. 344 366 .. 344 370 .. 0.89 11 ? -1.7 0.0 6.1 3.6e+03 29 38 .. 378 387 .. 377 399 .. 0.74 12 ! 11.0 0.0 0.00064 0.37 1 38 [. 424 467 .. 424 471 .. 0.79 13 ? 0.4 0.0 1.3 7.5e+02 3 22 .. 466 485 .. 464 485 .. 0.89 14 ! 11.3 0.0 0.00051 0.3 1 23 [. 504 526 .. 504 529 .. 0.95 15 ! 17.4 0.3 6.3e-06 0.0037 4 41 .. 547 590 .. 544 591 .. 0.91 16 ? 4.0 0.0 0.099 57 30 39 .. 746 755 .. 745 758 .. 0.90 17 ! 13.7 0.2 9.4e-05 0.055 3 23 .. 753 773 .. 751 773 .. 0.93 18 ! 10.6 0.0 0.00083 0.48 1 20 [. 791 810 .. 791 813 .. 0.94 19 ? 5.4 2.1 0.036 21 3 39 .. 833 875 .. 831 878 .. 0.72 20 ? 4.2 0.0 0.083 48 1 21 [. 911 931 .. 911 933 .. 0.88 21 ? -1.8 0.0 6.6 3.8e+03 30 39 .. 946 955 .. 945 957 .. 0.88 22 ? -0.8 0.0 3.1 1.8e+03 9 23 .. 959 973 .. 958 976 .. 0.88 23 ? 6.1 0.0 0.021 12 26 40 .. 1113 1127 .. 1111 1129 .. 0.86 24 ? 6.9 0.0 0.013 7.3 1 23 [. 1162 1184 .. 1162 1187 .. 0.88 25 ? 6.5 0.0 0.016 9.5 1 23 [. 1202 1224 .. 1202 1227 .. 0.91 26 ? 1.4 0.1 0.64 3.7e+02 30 38 .. 1237 1245 .. 1236 1249 .. 0.87 27 ? 2.4 0.1 0.32 1.8e+02 1 20 [. 1242 1261 .. 1242 1264 .. 0.85 28 ? 5.2 0.0 0.042 24 1 24 [. 1282 1305 .. 1282 1308 .. 0.90 29 ? 7.0 0.0 0.011 6.5 1 23 [. 1322 1344 .. 1322 1345 .. 0.91 30 ? -0.7 0.1 3 1.7e+03 30 39 .. 1357 1366 .. 1355 1368 .. 0.80 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.2 TPR_11 6 eqGkyeeAieaYkkAlkl 23 ++ ++ ++ie+Y+k lk+ FUN_000362-T1 29 SKSDFSKSIECYEKSLKI 46 677899**********98 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0018 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPd 26 G++y +q ++++Aie+Y++ lk+ + FUN_000362-T1 64 GRVYDSQSDFPKAIECYEESLKIAKE 89 788999****************9765 PP == domain 3 score: 3.9 bits; conditional E-value: 0.1 TPR_11 4 yyeqGkyeeAieaYkkAlkl 23 + +q ++ ++ie+Y+k lk+ FUN_000362-T1 107 FDSQSDFSKSIECYEKSLKI 126 5578999***********98 PP == domain 4 score: 2.3 bits; conditional E-value: 0.33 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G++y + ++++Ai+ Ykk lk+ FUN_000362-T1 184 GRVYDSESNFPKAIKFYKKSLKI 206 6777788899***********98 PP == domain 5 score: 0.7 bits; conditional E-value: 1.1 TPR_11 7 qGkyeeAieaYkkAlkl 23 + +++++ie+Y+k l + FUN_000362-T1 230 LSNFPKSIECYEKSLTI 246 5678999****998876 PP == domain 6 score: 2.6 bits; conditional E-value: 0.26 TPR_11 29 eayynLGlay 38 +ay+nLGl+y FUN_000362-T1 258 DAYLNLGLVY 267 79*******9 PP == domain 7 score: 10.3 bits; conditional E-value: 0.001 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykqG 42 G +y +q ++++Aie+Y+k lk+ + + ay+nLGl+y qG FUN_000362-T1 264 GLVYDSQSDFPKAIECYEKSLKIAREAGDrvregkAYLNLGLVYGSQG 311 67788999***************9998766666669999999999998 PP == domain 8 score: 3.7 bits; conditional E-value: 0.12 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G +y +qG + ++ie+Y+k l++ FUN_000362-T1 304 GLVYGSQGIFGKSIECYEKSLRI 326 778999*************9998 PP == domain 9 score: 1.2 bits; conditional E-value: 0.73 TPR_11 29 eayynLGlay 38 +a++nLGl+y FUN_000362-T1 338 DAFFNLGLVY 347 79*******9 PP == domain 10 score: 7.0 bits; conditional E-value: 0.011 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G +y +q ++++A+e+Y+k lk+ FUN_000362-T1 344 GLVYDSQSDFPKAVECYEKSLKI 366 67788999*************98 PP == domain 11 score: -1.7 bits; conditional E-value: 6.1 TPR_11 29 eayynLGlay 38 +ay+nLG +y FUN_000362-T1 378 DAYLNLGCLY 387 6777777555 PP == domain 12 score: 11.0 bits; conditional E-value: 0.00064 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnae......ayynLGlay 38 G +y++q +++++ie+Y++ lk+ + + ay+nLG++y FUN_000362-T1 424 GLVYFSQSNFPKSIECYEETLKIVREAGDrvregkAYFNLGFVY 467 889******************99887654444444777777777 PP == domain 13 score: 0.4 bits; conditional E-value: 1.3 TPR_11 3 ayyeqGkyeeAieaYkkAlk 22 +y +q +++++ie+++k lk FUN_000362-T1 466 VYNSQSEFPKSIECFEKSLK 485 799************99876 PP == domain 14 score: 11.3 bits; conditional E-value: 0.00051 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G++y++q ++ +Aie+Y++ lk+ FUN_000362-T1 504 GRVYFSQSDFCKAIECYEESLKI 526 99*****************9998 PP == domain 15 score: 17.4 bits; conditional E-value: 6.3e-06 TPR_11 4 yyeqGkyeeAieaYkkAlkldPdnae......ayynLGlayykq 41 +y+qG+++ Aie+Y+k lk+ ++ ++ +y+nLG++yy q FUN_000362-T1 547 FYSQGDFPIAIECYEKSLKIASEGVDwategkVYLNLGHVYYSQ 590 9************************87777779*********87 PP == domain 16 score: 4.0 bits; conditional E-value: 0.099 TPR_11 30 ayynLGlayy 39 +y+nLG++yy FUN_000362-T1 746 FYFNLGVVYY 755 7********9 PP == domain 17 score: 13.7 bits; conditional E-value: 9.4e-05 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 +yy++ ++ +Ai++Y+kAl++ FUN_000362-T1 753 VYYSRSEFRKAIKCYEKALNI 773 8******************97 PP == domain 18 score: 10.6 bits; conditional E-value: 0.00083 TPR_11 1 GdayyeqGkyeeAieaYkkA 20 G+ay + +++++Aie+Y+k FUN_000362-T1 791 GNAYKSHNDFPKAIECYEKS 810 9****************996 PP == domain 19 score: 5.4 bits; conditional E-value: 0.036 TPR_11 3 ayyeqGkyeeAieaYkkAlkl......dPdnaeayynLGlayy 39 +y + ++++Aie Y+k l++ + + +ay+nLG+ay+ FUN_000362-T1 833 VYNSCSDLPKAIEYYEKSLNIareagdKAKEGNAYLNLGNAYM 875 6778888889999999998883333333445589*******97 PP == domain 20 score: 4.2 bits; conditional E-value: 0.083 TPR_11 1 GdayyeqGkyeeAieaYkkAl 21 G +y +G+ +Aie+Y+k l FUN_000362-T1 911 GSVYLCRGDRSKAIECYEKSL 931 7789999***********976 PP == domain 21 score: -1.8 bits; conditional E-value: 6.6 TPR_11 30 ayynLGlayy 39 ay+ LG++y FUN_000362-T1 946 AYFTLGVVYE 955 89******96 PP == domain 22 score: -0.8 bits; conditional E-value: 3.1 TPR_11 9 kyeeAieaYkkAlkl 23 ++++Ai +Y k l++ FUN_000362-T1 959 DLTNAIDCYVKSLNI 973 5789******99987 PP == domain 23 score: 6.1 bits; conditional E-value: 0.021 TPR_11 26 dnaeayynLGlayyk 40 + aeay++LG++y+ FUN_000362-T1 1113 TKAEAYFHLGAVYLS 1127 579**********86 PP == domain 24 score: 6.9 bits; conditional E-value: 0.013 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G +y+ q ++++Aie+Y+k l++ FUN_000362-T1 1162 GTVYHFQSDFPKAIECYEKSLDI 1184 56788899***********9987 PP == domain 25 score: 6.5 bits; conditional E-value: 0.016 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G +y +++++++Aie Y+k l++ FUN_000362-T1 1202 GTVYKSRNDLPKAIEFYEKSLNI 1224 6789***************9987 PP == domain 26 score: 1.4 bits; conditional E-value: 0.64 TPR_11 30 ayynLGlay 38 ay+nLGl+y FUN_000362-T1 1237 AYLNLGLVY 1245 8*******9 PP == domain 27 score: 2.4 bits; conditional E-value: 0.32 TPR_11 1 GdayyeqGkyeeAieaYkkA 20 G +y +q ++ +Aie+Y+k FUN_000362-T1 1242 GLVYDSQSDFRNAIECYEKS 1261 66777899999******996 PP == domain 28 score: 5.2 bits; conditional E-value: 0.042 TPR_11 1 GdayyeqGkyeeAieaYkkAlkld 24 G +y +++++++A+e Y+k l+++ FUN_000362-T1 1282 GTVYKSRNDLPKAMEFYEKSLNIS 1305 6789*****************997 PP == domain 29 score: 7.0 bits; conditional E-value: 0.011 TPR_11 1 GdayyeqGkyeeAieaYkkAlkl 23 G +y +q ++ +Aie+Y+k l++ FUN_000362-T1 1322 GLIYDSQSNFSKAIECYEKSLNI 1344 7788899************9987 PP == domain 30 score: -0.7 bits; conditional E-value: 3 TPR_11 30 ayynLGlayy 39 ay+ LG +y FUN_000362-T1 1357 AYFSLGIVYK 1366 7999998885 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 0.0 0.0071 4.1 31 60 .. 57 86 .. 32 91 .. 0.83 2 ! 13.7 0.0 0.00016 0.095 1 62 [. 61 128 .. 61 131 .. 0.92 3 ? -1.5 0.0 8.8 5.1e+03 37 61 .. 183 207 .. 179 211 .. 0.82 4 ! 9.3 0.0 0.0038 2.2 3 61 .. 223 287 .. 221 293 .. 0.71 5 ! 9.7 0.0 0.0028 1.7 1 62 [. 261 328 .. 261 332 .. 0.91 6 ? 6.7 0.0 0.024 14 3 60 .. 303 366 .. 301 372 .. 0.72 7 ? 5.2 0.0 0.074 43 2 52 .. 342 398 .. 341 412 .. 0.83 8 ? 7.2 0.0 0.017 9.9 22 58 .. 406 444 .. 401 453 .. 0.78 9 ? 7.0 0.0 0.02 11 1 58 [. 421 484 .. 421 492 .. 0.86 10 ! 8.9 0.0 0.0052 3 12 61 .. 472 527 .. 467 533 .. 0.79 11 ! 15.0 0.0 6.1e-05 0.035 1 62 [. 501 568 .. 501 571 .. 0.92 12 ? 4.4 0.0 0.13 73 32 58 .. 745 771 .. 739 776 .. 0.74 13 ! 14.5 0.0 9.3e-05 0.054 1 58 [. 788 851 .. 788 861 .. 0.89 14 ? -0.6 0.1 4.7 2.7e+03 21 50 .. 852 883 .. 848 898 .. 0.74 15 ? 1.9 0.0 0.79 4.6e+02 31 58 .. 904 931 .. 868 940 .. 0.77 16 ? -0.8 0.1 5.4 3.1e+03 1 22 [. 995 1016 .. 981 1022 .. 0.64 17 ? 0.5 0.1 2.2 1.3e+03 31 51 .. 1115 1135 .. 1108 1137 .. 0.84 18 ? 5.1 0.0 0.079 46 10 58 .. 1168 1222 .. 1159 1230 .. 0.77 19 ! 9.7 0.0 0.0029 1.7 1 58 [. 1239 1302 .. 1239 1312 .. 0.87 20 ? 2.6 0.0 0.48 2.8e+02 2 52 .. 1320 1376 .. 1319 1390 .. 0.61 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0071 TPR_16 31 aaAllglGlallrqgrlaeAaaayraalra 60 +A+l+lG+++ q ++++A++ y++ l++ FUN_000362-T1 57 GDAYLNLGRVYDSQSDFPKAIECYEESLKI 86 589999999999999999999999988765 PP == domain 2 score: 13.7 bits; conditional E-value: 0.00016 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalraap 62 l l+r + + d++ A++++e+ l+ + A+++lGl++ q ++ + ++ y++ l++a+ FUN_000362-T1 61 LNLGRVYDSQSDFPKAIECYEESLKIAkeagdrVRKGKAYFNLGLVFDSQSDFSKSIECYEKSLKIAS 128 679**********************99999***8899********************99999887665 PP == domain 3 score: -1.5 bits; conditional E-value: 8.8 TPR_16 37 lGlallrqgrlaeAaaayraalraa 61 G+++ ++++A+++y++ l++a FUN_000362-T1 183 VGRVYDSESNFPKAIKFYKKSLKIA 207 5888899999********9998765 PP == domain 4 score: 9.3 bits; conditional E-value: 0.0038 TPR_16 3 laraalaagdyddAaaal.eaalrrn.....PeaaaAllglGlallrqgrlaeAaaayraalraa 61 l+r + + +++ +++++ + ++ + +A+l+lGl++ q ++++A++ y++ l++a FUN_000362-T1 223 LGRVYDTLSNFPKSIECYeKSLTIAKeagdrVTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKIA 287 566666666666666666333333335666644678********************999988655 PP == domain 5 score: 9.7 bits; conditional E-value: 0.0028 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalraap 62 l l++ + + d++ A++++e l+ + A+l+lGl++ qg + + ++ y++ lr+a+ FUN_000362-T1 261 LNLGLVYDSQSDFPKAIECYEKSLKIAreagdrVREGKAYLNLGLVYGSQGIFGKSIECYEKSLRIAS 328 579999***************9999888999**8899*****************99999999998765 PP == domain 6 score: 6.7 bits; conditional E-value: 0.024 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalra 60 l++ + +g + +++++e lr +A ++lGl++ q ++++A++ y++ l++ FUN_000362-T1 303 LGLVYGSQGIFGKSIECYEKSLRIAseggdrATEGDAFFNLGLVYDSQSDFPKAVECYEKSLKI 366 55666666666666666655555555666665567999****************9999988865 PP == domain 7 score: 5.2 bits; conditional E-value: 0.074 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaa 52 l++ + + d++ A++++e l+ + +A+l+lG ++ ++++A++ FUN_000362-T1 342 NLGLVYDSQSDFPKAVECYEKSLKIAkeagdrTLEGDAYLNLGCLYNSESDFPKAIE 398 688999999999999999999999888888886678888888888888888888875 PP == domain 8 score: 7.2 bits; conditional E-value: 0.017 TPR_16 22 aalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 a++++ + A+l+lGl+++ q ++++ ++ y++ l FUN_000362-T1 406 IAREAGdpVREGKAYLNLGLVYFSQSNFPKSIECYEETL 444 556666665678899999999999999999999888866 PP == domain 9 score: 7.0 bits; conditional E-value: 0.02 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l l++ ++ + +++ +++++e+ l+ + A+++lG ++ q ++++ ++ +++ l FUN_000362-T1 421 LNLGLVYFSQSNFPKSIECYEETLKIVreagdrVREGKAYFNLGFVYNSQSEFPKSIECFEKSL 484 67999******************99888889997889999999999999999999998888776 PP == domain 10 score: 8.9 bits; conditional E-value: 0.0052 TPR_16 12 dyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalraa 61 +++ +++++e l+ +A+l+lG++++ q ++ +A++ y++ l++a FUN_000362-T1 472 EFPKSIECFEKSLKTAsegrdrATEGDAYLNLGRVYFSQSDFCKAIECYEESLKIA 527 566666667777766666667766789*******************9999988655 PP == domain 11 score: 15.0 bits; conditional E-value: 6.1e-05 TPR_16 1 lalaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalraap 62 l l+r ++ + d+ A++++e+ l+ + +A+l+ Gl ++ qg+++ A++ y++ l++a+ FUN_000362-T1 501 LNLGRVYFSQSDFCKAIECYEESLKIAreagnrDLEGDAYLNVGLFFYSQGDFPIAIECYEKSLKIAS 568 679*******************999888999**99**********************99999887765 PP == domain 12 score: 4.4 bits; conditional E-value: 0.13 TPR_16 32 aAllglGlallrqgrlaeAaaayraal 58 +++++lG++++ + ++ +A++ y++al FUN_000362-T1 745 RFYFNLGVVYYSRSEFRKAIKCYEKAL 771 677777777777777777777777665 PP == domain 13 score: 14.5 bits; conditional E-value: 9.3e-05 TPR_16 1 lalaraalaagdyddAaaal.eaalrrn.....PeaaaAllglGlallrqgrlaeAaaayraal 58 l+l++a+ ++d++ A++++ + ++ ++ + A ++lG ++ +l++A+++y++ l FUN_000362-T1 788 LKLGNAYKSHNDFPKAIECYeKSLIIARragdvVREGNAFFNLGIVYNSCSDLPKAIEYYEKSL 851 689*****************77777777899**889************************9987 PP == domain 14 score: -0.6 bits; conditional E-value: 4.7 TPR_16 21 eaalrrn..PeaaaAllglGlallrqgrlaeA 50 a++++ A+l+lG a+ + ++A FUN_000362-T1 852 NIAREAGdkAKEGNAYLNLGNAYMSHDESPKA 883 55666666667788999999999876665555 PP == domain 15 score: 1.9 bits; conditional E-value: 0.79 TPR_16 31 aaAllglGlallrqgrlaeAaaayraal 58 A ++lG ++l +g+ +A++ y++ l FUN_000362-T1 904 GKANYNLGSVYLCRGDRSKAIECYEKSL 931 5688888888888888888888777766 PP == domain 16 score: -0.8 bits; conditional E-value: 5.4 TPR_16 1 lalaraalaagdyddAaaalea 22 lal++ + a g+ + a+ ea FUN_000362-T1 995 LALGDVLKATGNREVGAHTVEA 1016 4556666666666666665555 PP == domain 17 score: 0.5 bits; conditional E-value: 2.2 TPR_16 31 aaAllglGlallrqgrlaeAa 51 a+A++ lG ++l + ++ +A+ FUN_000362-T1 1115 AEAYFHLGAVYLSLSDFRKAI 1135 789999999999999888887 PP == domain 18 score: 5.1 bits; conditional E-value: 0.079 TPR_16 10 agdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 + d++ A++++e l+ +++lG ++ +++l++A+++y++ l FUN_000362-T1 1168 QSDFPKAIECYEKSLDIAreagdrATEGSGYFNLGTVYKSRNDLPKAIEFYEKSL 1222 67777777777777766665667766677899999999999**********9876 PP == domain 19 score: 9.7 bits; conditional E-value: 0.0029 TPR_16 1 lalaraalaagdyddAaaal.eaalrrn.....PeaaaAllglGlallrqgrlaeAaaayraal 58 l l++ + + d++ A++++ + +l + +++lG ++ +++l++A ++y++ l FUN_000362-T1 1239 LNLGLVYDSQSDFRNAIECYeKSLLIATkagdrAAEGSGYFNLGTVYKSRNDLPKAMEFYEKSL 1302 579999**************7777777788899889999*********************9977 PP == domain 20 score: 2.6 bits; conditional E-value: 0.48 TPR_16 2 alaraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaa 52 l++ + + ++ A++++e l A++ lG ++ +++a+A + FUN_000362-T1 1320 NLGLIYDSQSNFSKAIECYEKSLNIAweagdqATEGKAYFSLGIVYKLHKDFAKAFE 1376 567777777788888888765543333555554455566666666666666666655 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.015 8.8 12 34 .] 56 78 .. 39 78 .. 0.89 2 ? 0.1 0.0 3.2 1.9e+03 14 32 .. 98 116 .. 96 118 .. 0.80 3 ? -1.0 0.0 7.4 4.3e+03 14 32 .. 218 236 .. 216 238 .. 0.82 4 ? 5.9 0.0 0.044 25 13 34 .] 257 278 .. 255 278 .. 0.91 5 ? 1.0 0.0 1.7 9.9e+02 14 28 .. 298 312 .. 296 326 .. 0.81 6 ? 4.6 0.0 0.12 70 13 33 .. 337 357 .. 333 358 .. 0.89 7 ? 5.2 0.0 0.075 44 14 34 .] 378 398 .. 374 398 .. 0.91 8 ? 1.3 0.0 1.3 7.8e+02 14 33 .. 418 437 .. 416 438 .. 0.84 9 ? 3.6 0.0 0.24 1.4e+02 14 32 .. 458 476 .. 456 478 .. 0.84 10 ? 2.7 0.0 0.49 2.9e+02 13 28 .. 497 512 .. 494 522 .. 0.83 11 ? -0.7 0.0 5.9 3.4e+03 14 28 .. 578 592 .. 575 596 .. 0.79 12 ? 2.5 0.0 0.53 3.1e+02 14 33 .. 745 764 .. 742 773 .. 0.83 13 ? 3.9 0.0 0.19 1.1e+02 14 34 .] 785 805 .. 782 805 .. 0.92 14 ? 4.5 0.0 0.13 75 14 34 .] 825 845 .. 823 845 .. 0.92 15 ? 2.6 0.1 0.51 3e+02 14 32 .. 865 883 .. 862 885 .. 0.85 16 ? 2.1 0.0 0.75 4.4e+02 14 32 .. 905 923 .. 901 925 .. 0.80 17 ? -1.1 0.0 7.9 4.6e+03 14 24 .. 945 955 .. 942 964 .. 0.83 18 ? -0.8 0.1 6.3 3.6e+03 16 32 .. 987 1003 .. 985 1006 .. 0.70 19 ? 6.5 0.0 0.028 16 12 34 .] 1114 1136 .. 1112 1136 .. 0.91 20 ? -0.2 0.0 4.1 2.4e+03 15 34 .] 1157 1176 .. 1153 1176 .. 0.86 21 ? 5.8 0.0 0.047 27 15 34 .] 1197 1216 .. 1193 1216 .. 0.90 22 ? 1.9 0.0 0.85 5e+02 14 33 .. 1236 1255 .. 1233 1256 .. 0.85 23 ? 4.1 0.0 0.17 1e+02 15 32 .. 1277 1294 .. 1275 1296 .. 0.89 24 ? -0.7 0.0 5.8 3.4e+03 18 34 .] 1320 1336 .. 1317 1344 .. 0.71 25 ? 3.2 0.0 0.34 2e+02 13 32 .. 1355 1374 .. 1351 1376 .. 0.88 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.015 TPR_17 12 nadayynLArlllnnGqleeAlq 34 day nL+r++ + ++ +A++ FUN_000362-T1 56 EGDAYLNLGRVYDSQSDFPKAIE 78 579****************9985 PP == domain 2 score: 0.1 bits; conditional E-value: 3.2 TPR_17 14 dayynLArlllnnGqleeA 32 +ay+nL+ + + ++ + FUN_000362-T1 98 KAYFNLGLVFDSQSDFSKS 116 69*****999888877665 PP == domain 3 score: -1.0 bits; conditional E-value: 7.4 TPR_17 14 dayynLArlllnnGqleeA 32 +ay L+r++ + ++ + FUN_000362-T1 218 KAYLSLGRVYDTLSNFPKS 236 69********988887765 PP == domain 4 score: 5.9 bits; conditional E-value: 0.044 TPR_17 13 adayynLArlllnnGqleeAlq 34 day nL+ ++ + ++ +A++ FUN_000362-T1 257 GDAYLNLGLVYDSQSDFPKAIE 278 69****************9985 PP == domain 5 score: 1.0 bits; conditional E-value: 1.7 TPR_17 14 dayynLArlllnnGq 28 +ay nL+ ++ +G FUN_000362-T1 298 KAYLNLGLVYGSQGI 312 699******997774 PP == domain 6 score: 4.6 bits; conditional E-value: 0.12 TPR_17 13 adayynLArlllnnGqleeAl 33 da++nL+ ++ + ++ +A+ FUN_000362-T1 337 GDAFFNLGLVYDSQSDFPKAV 357 699*************99997 PP == domain 7 score: 5.2 bits; conditional E-value: 0.075 TPR_17 14 dayynLArlllnnGqleeAlq 34 day nL++l+ ++ +A++ FUN_000362-T1 378 DAYLNLGCLYNSESDFPKAIE 398 8***********999999985 PP == domain 8 score: 1.3 bits; conditional E-value: 1.3 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay nL+ ++ + ++ + + FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSI 437 69********9999887765 PP == domain 9 score: 3.6 bits; conditional E-value: 0.24 TPR_17 14 dayynLArlllnnGqleeA 32 +ay+nL++++ + ++ + FUN_000362-T1 458 KAYFNLGFVYNSQSEFPKS 476 69********999887766 PP == domain 10 score: 2.7 bits; conditional E-value: 0.49 TPR_17 13 adayynLArlllnnGq 28 day nL+r++ + + FUN_000362-T1 497 GDAYLNLGRVYFSQSD 512 69*********98776 PP == domain 11 score: -0.7 bits; conditional E-value: 5.9 TPR_17 14 dayynLArlllnnGq 28 ++y nL++++ + + FUN_000362-T1 578 KVYLNLGHVYYSQSD 592 6899****9987766 PP == domain 12 score: 2.5 bits; conditional E-value: 0.53 TPR_17 14 dayynLArlllnnGqleeAl 33 +y+nL++++ + ++ +A+ FUN_000362-T1 745 RFYFNLGVVYYSRSEFRKAI 764 589*******9888877776 PP == domain 13 score: 3.9 bits; conditional E-value: 0.19 TPR_17 14 dayynLArlllnnGqleeAlq 34 d+y L+++++ +++ +A++ FUN_000362-T1 785 DSYLKLGNAYKSHNDFPKAIE 805 89***************9985 PP == domain 14 score: 4.5 bits; conditional E-value: 0.13 TPR_17 14 dayynLArlllnnGqleeAlq 34 +a++nL++++ + +l +A++ FUN_000362-T1 825 NAFFNLGIVYNSCSDLPKAIE 845 699***************985 PP == domain 15 score: 2.6 bits; conditional E-value: 0.51 TPR_17 14 dayynLArlllnnGqleeA 32 +ay nL++++ +++ +A FUN_000362-T1 865 NAYLNLGNAYMSHDESPKA 883 79********988888877 PP == domain 16 score: 2.1 bits; conditional E-value: 0.75 TPR_17 14 dayynLArlllnnGqleeA 32 +a ynL+ ++l +G+ +A FUN_000362-T1 905 KANYNLGSVYLCRGDRSKA 923 799********99985555 PP == domain 17 score: -1.1 bits; conditional E-value: 7.9 TPR_17 14 dayynLArlll 24 +ay+ L+++++ FUN_000362-T1 945 KAYFTLGVVYE 955 79*******97 PP == domain 18 score: -0.8 bits; conditional E-value: 6.3 TPR_17 16 yynLArlllnnGqleeA 32 ++L++ +l +G+ +A FUN_000362-T1 987 NQYLGVSYLALGDVLKA 1003 56788888888876665 PP == domain 19 score: 6.5 bits; conditional E-value: 0.028 TPR_17 12 nadayynLArlllnnGqleeAlq 34 a+ay+ L+ ++l + ++ +A++ FUN_000362-T1 1114 KAEAYFHLGAVYLSLSDFRKAIE 1136 689***************99985 PP == domain 20 score: -0.2 bits; conditional E-value: 4.1 TPR_17 15 ayynLArlllnnGqleeAlq 34 a + L+++++ + ++ +A++ FUN_000362-T1 1157 ASFHLGTVYHFQSDFPKAIE 1176 6689************9985 PP == domain 21 score: 5.8 bits; conditional E-value: 0.047 TPR_17 15 ayynLArlllnnGqleeAlq 34 y+nL+++++ +++l +A++ FUN_000362-T1 1197 GYFNLGTVYKSRNDLPKAIE 1216 6****************985 PP == domain 22 score: 1.9 bits; conditional E-value: 0.85 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay nL+ ++ + ++ A+ FUN_000362-T1 1236 KAYLNLGLVYDSQSDFRNAI 1255 79*********999887776 PP == domain 23 score: 4.1 bits; conditional E-value: 0.17 TPR_17 15 ayynLArlllnnGqleeA 32 y+nL+++++ +++l +A FUN_000362-T1 1277 GYFNLGTVYKSRNDLPKA 1294 59************9998 PP == domain 24 score: -0.7 bits; conditional E-value: 5.8 TPR_17 18 nLArlllnnGqleeAlq 34 nL+ ++ + ++ +A++ FUN_000362-T1 1320 NLGLIYDSQSNFSKAIE 1336 67777777777666654 PP == domain 25 score: 3.2 bits; conditional E-value: 0.34 TPR_17 13 adayynLArlllnnGqleeA 32 +ay+ L+++++ +++++A FUN_000362-T1 1355 GKAYFSLGIVYKLHKDFAKA 1374 589**********9999998 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.94 5.5e+02 69 89 .. 30 50 .. 22 61 .. 0.85 2 ? 6.3 0.0 0.027 16 67 92 .. 68 93 .. 64 102 .. 0.88 3 ? 4.1 0.0 0.13 73 67 88 .. 108 129 .. 106 136 .. 0.91 4 ? 6.0 0.0 0.034 19 67 90 .. 148 171 .. 140 179 .. 0.88 5 ? 5.2 0.1 0.056 33 68 92 .. 189 213 .. 184 260 .. 0.67 6 ? 6.1 0.0 0.03 18 67 91 .. 268 292 .. 266 303 .. 0.88 7 ? -1.6 0.0 7.3 4.3e+03 69 88 .. 310 329 .. 302 337 .. 0.85 8 ? 7.1 0.0 0.015 8.7 67 92 .. 348 373 .. 346 410 .. 0.89 9 ? -0.4 0.0 3.2 1.9e+03 69 91 .. 430 452 .. 427 461 .. 0.86 10 ? 2.1 0.0 0.51 3e+02 67 90 .. 468 491 .. 464 501 .. 0.85 11 ? 4.5 0.0 0.094 54 69 92 .. 510 533 .. 506 542 .. 0.89 12 ? -0.6 0.0 3.6 2.1e+03 69 91 .. 550 572 .. 546 582 .. 0.87 13 ? -1.2 0.0 5.6 3.2e+03 71 91 .. 759 779 .. 755 810 .. 0.75 14 ? -1.5 0.0 6.8 3.9e+03 69 87 .. 797 815 .. 786 823 .. 0.81 15 ? 5.3 0.0 0.054 32 70 93 .. 838 861 .. 833 874 .. 0.85 16 ? -0.1 0.0 2.5 1.5e+03 69 92 .. 957 980 .. 953 989 .. 0.84 17 ? 5.1 0.0 0.062 36 68 92 .. 1167 1191 .. 1163 1196 .. 0.87 18 ? 1.7 0.0 0.69 4e+02 69 88 .. 1208 1227 .. 1202 1230 .. 0.86 19 ? 2.1 0.0 0.55 3.2e+02 67 92 .. 1246 1271 .. 1244 1276 .. 0.86 20 ? 3.9 0.0 0.15 85 69 92 .. 1288 1311 .. 1282 1317 .. 0.84 21 ? 3.5 0.0 0.19 1.1e+02 67 89 .. 1326 1348 .. 1324 1357 .. 0.86 22 ? 2.0 0.0 0.57 3.3e+02 69 89 .. 1368 1388 .. 1364 1403 .. 0.87 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.94 DUF7018 69 qkllekaidhyekslklieea 89 + ++ k+i+ yekslk++ e FUN_000362-T1 30 KSDFSKSIECYEKSLKIASEG 50 5799************99875 PP == domain 2 score: 6.3 bits; conditional E-value: 0.027 DUF7018 67 dvqkllekaidhyekslklieeavek 92 d q ++ kai+ ye+slk+++ea ++ FUN_000362-T1 68 DSQSDFPKAIECYEESLKIAKEAGDR 93 88*******************99665 PP == domain 3 score: 4.1 bits; conditional E-value: 0.13 DUF7018 67 dvqkllekaidhyekslkliee 88 d q ++ k+i+ yekslk++ e FUN_000362-T1 108 DSQSDFSKSIECYEKSLKIASE 129 78****************9876 PP == domain 4 score: 6.0 bits; conditional E-value: 0.034 DUF7018 67 dvqkllekaidhyekslklieeav 90 + q ++ k i++yekslk+++ea FUN_000362-T1 148 ESQSDFAKPIQFYEKSLKIAREAG 171 68*****************99985 PP == domain 5 score: 5.2 bits; conditional E-value: 0.056 DUF7018 68 vqkllekaidhyekslklieeavek 92 ++ kai++y+kslk++++a ++ FUN_000362-T1 189 SESNFPKAIKFYKKSLKIAKKAGDR 213 5678899999999999999998766 PP == domain 6 score: 6.1 bits; conditional E-value: 0.03 DUF7018 67 dvqkllekaidhyekslklieeave 91 d q ++ kai+ yekslk+++ea + FUN_000362-T1 268 DSQSDFPKAIECYEKSLKIAREAGD 292 78******************99865 PP == domain 7 score: -1.6 bits; conditional E-value: 7.3 DUF7018 69 qkllekaidhyekslkliee 88 q + k+i+ yeksl ++ e FUN_000362-T1 310 QGIFGKSIECYEKSLRIASE 329 77899**********99877 PP == domain 8 score: 7.1 bits; conditional E-value: 0.015 DUF7018 67 dvqkllekaidhyekslklieeavek 92 d q ++ ka++ yekslk+++ea ++ FUN_000362-T1 348 DSQSDFPKAVECYEKSLKIAKEAGDR 373 78********************9776 PP == domain 9 score: -0.4 bits; conditional E-value: 3.2 DUF7018 69 qkllekaidhyekslklieeave 91 q ++ k+i+ ye++lk+++ea + FUN_000362-T1 430 QSNFPKSIECYEETLKIVREAGD 452 88999************999865 PP == domain 10 score: 2.1 bits; conditional E-value: 0.51 DUF7018 67 dvqkllekaidhyekslklieeav 90 + q ++ k+i+ +ekslk++ e FUN_000362-T1 468 NSQSEFPKSIECFEKSLKTASEGR 491 6899**************998865 PP == domain 11 score: 4.5 bits; conditional E-value: 0.094 DUF7018 69 qkllekaidhyekslklieeavek 92 q ++ kai+ ye+slk+++ea ++ FUN_000362-T1 510 QSDFCKAIECYEESLKIAREAGNR 533 99****************999776 PP == domain 12 score: -0.6 bits; conditional E-value: 3.6 DUF7018 69 qkllekaidhyekslklieeave 91 q ++ ai+ yekslk++ e v+ FUN_000362-T1 550 QGDFPIAIECYEKSLKIASEGVD 572 889999***********999876 PP == domain 13 score: -1.2 bits; conditional E-value: 5.6 DUF7018 71 llekaidhyekslklieeave 91 ++ kai+ yek+l++ e+ e FUN_000362-T1 759 EFRKAIKCYEKALNIFTEVGE 779 678888888888888777654 PP == domain 14 score: -1.5 bits; conditional E-value: 6.8 DUF7018 69 qkllekaidhyekslklie 87 +++ kai+ yeksl +++ FUN_000362-T1 797 HNDFPKAIECYEKSLIIAR 815 57999********997765 PP == domain 15 score: 5.3 bits; conditional E-value: 0.054 DUF7018 70 kllekaidhyekslklieeavekk 93 +l kai++yeksl++++ea +k FUN_000362-T1 838 SDLPKAIEYYEKSLNIAREAGDKA 861 6899**************997764 PP == domain 16 score: -0.1 bits; conditional E-value: 2.5 DUF7018 69 qkllekaidhyekslklieeavek 92 + +l++aid y ksl++++ea ++ FUN_000362-T1 957 RCDLTNAIDCYVKSLNIAREAGDR 980 67999*************998665 PP == domain 17 score: 5.1 bits; conditional E-value: 0.062 DUF7018 68 vqkllekaidhyekslklieeavek 92 q ++ kai+ yeksl++++ea ++ FUN_000362-T1 1167 FQSDFPKAIECYEKSLDIAREAGDR 1191 699****************998665 PP == domain 18 score: 1.7 bits; conditional E-value: 0.69 DUF7018 69 qkllekaidhyekslkliee 88 +++l kai++yeksl++++e FUN_000362-T1 1208 RNDLPKAIEFYEKSLNIARE 1227 57999**********99876 PP == domain 19 score: 2.1 bits; conditional E-value: 0.55 DUF7018 67 dvqkllekaidhyekslklieeavek 92 d q ++ +ai+ yeksl ++ +a ++ FUN_000362-T1 1246 DSQSDFRNAIECYEKSLLIATKAGDR 1271 78***************999888665 PP == domain 20 score: 3.9 bits; conditional E-value: 0.15 DUF7018 69 qkllekaidhyekslklieeavek 92 +++l ka+++yeksl++ +ea ++ FUN_000362-T1 1288 RNDLPKAMEFYEKSLNISREAGDR 1311 57999***********99998655 PP == domain 21 score: 3.5 bits; conditional E-value: 0.19 DUF7018 67 dvqkllekaidhyekslklieea 89 d q ++ kai+ yeksl+++ ea FUN_000362-T1 1326 DSQSNFSKAIECYEKSLNIAWEA 1348 789***************98776 PP == domain 22 score: 2.0 bits; conditional E-value: 0.57 DUF7018 69 qkllekaidhyekslklieea 89 k++ ka + +eksl++++ea FUN_000362-T1 1368 HKDFAKAFECFEKSLNIAREA 1388 699**************9987 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.0 0.0011 0.63 16 110 .. 37 134 .. 28 138 .. 0.81 2 ? -0.5 0.0 2.1 1.2e+03 20 64 .. 201 245 .. 189 255 .. 0.75 3 ! 11.9 0.0 0.00033 0.19 16 139 .. 237 363 .. 227 375 .. 0.87 4 ? 1.8 0.0 0.4 2.3e+02 37 65 .. 418 446 .. 360 466 .. 0.81 5 ! 7.5 0.0 0.0072 4.2 37 107 .. 418 488 .. 401 495 .. 0.90 6 ! 7.6 0.1 0.0067 3.9 14 64 .. 475 525 .. 470 533 .. 0.88 7 ? 4.7 0.0 0.054 31 37 64 .. 538 565 .. 523 621 .. 0.77 8 ? 4.9 0.1 0.047 27 38 67 .. 746 775 .. 723 781 .. 0.78 9 ? 6.1 0.0 0.02 12 38 97 .. 786 845 .. 784 852 .. 0.85 10 ? 5.1 0.1 0.04 23 15 63 .. 843 891 .. 838 902 .. 0.88 11 ! 11.7 0.2 0.00038 0.22 37 132 .. 905 1003 .. 888 1006 .. 0.81 12 ? 1.2 0.1 0.64 3.7e+02 35 61 .. 1114 1140 .. 1098 1149 .. 0.80 13 ! 13.8 0.0 8.2e-05 0.048 41 139 .. 1160 1261 .. 1142 1270 .. 0.89 14 ! 10.9 0.1 0.00067 0.39 38 140 .. 1277 1382 .. 1273 1387 .. 0.91 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.0011 RPN7 16 leeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliek...ggd 108 +e e+ lk a e +a+++l+ y + d+ +A+++ye+ ++ + +g + + ++g+ f + sk++e ++ ++ ggd FUN_000362-T1 37 IECYEKSLKIASEGGDRATEGDAYLNLGRVYDSQSDFPKAIECYEESLKIAKEAGDRVRKGKAYFNLGLVFDSQSDFSKSIECYEKSLKIaseGGD 132 55566666655555555556689*************************************************999999999877766553222778 PP RPN7 109 we 110 w FUN_000362-T1 133 WA 134 86 PP == domain 2 score: -0.5 bits; conditional E-value: 2.1 RPN7 20 eaelkdakenlgkeeirraledlaehyakigdlenAlkayerare 64 ++ lk ak+ +a++ l+ y + ++ +++++ye+ + FUN_000362-T1 201 KKSLKIAKKAGDRVREIKAYLSLGRVYDTLSNFPKSIECYEKSLT 245 556666666666666667899999999999999999999999765 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00033 RPN7 16 leeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaks...liekggd 108 +e e+ l+ ake +a+++l+ y + d+ +A+++ye+ ++ + +g + + +++g+ ++ k++e ++ + ++ggd FUN_000362-T1 237 IECYEKSLTIAKEAGDRVTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKIAREAGDRVREGKAYLNLGLVYGSQGIFGKSIECYEKslrIASEGGD 332 55567777777777778888899*********************************************************9866651115678999 PP RPN7 109 werrnrlkvyeGlaalairkfkeAaklllds 139 + ++ Gl + ++ +f +A ++ +s FUN_000362-T1 333 RATEGDAFFNLGLVYDSQSDFPKAVECYEKS 363 9999999999999999999999999987666 PP == domain 4 score: 1.8 bits; conditional E-value: 0.4 RPN7 37 raledlaehyakigdlenAlkayerarek 65 +a+++l+ y++ ++ +++++ye++++ FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLKI 446 57888888999999999999999988765 PP == domain 5 score: 7.5 bits; conditional E-value: 0.0072 RPN7 37 raledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliekgg 107 +a+++l+ y++ ++ +++++ye++++ + +g + + ++g+ +n + k++e ++ ++++ FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLKIVREAGDRVREGKAYFNLGFVYNSQSEFPKSIECFEKSLKTAS 488 6899*******************************************************999998888764 PP == domain 6 score: 7.6 bits; conditional E-value: 0.0067 RPN7 14 keleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerare 64 k +e +e+ lk a e + +a+++l+ y++ d+ +A+++ye+ ++ FUN_000362-T1 475 KSIECFEKSLKTASEGRDRATEGDAYLNLGRVYFSQSDFCKAIECYEESLK 525 56788999999999999999999************************9765 PP == domain 7 score: 4.7 bits; conditional E-value: 0.054 RPN7 37 raledlaehyakigdlenAlkayerare 64 +a+++ + ++++ gd+ A+++ye+ ++ FUN_000362-T1 538 DAYLNVGLFFYSQGDFPIAIECYEKSLK 565 58999*******************9665 PP == domain 8 score: 4.9 bits; conditional E-value: 0.047 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 + +l+ y++ ++++A+k+ye+a++ t FUN_000362-T1 746 FYFNLGVVYYSRSEFRKAIKCYEKALNIFT 775 57789999****************987665 PP == domain 9 score: 6.1 bits; conditional E-value: 0.02 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskyle 97 +++l++ y ++ d+ +A+++ye+ + + +g ++ ++ ++gi +n ++ + k +e FUN_000362-T1 786 SYLKLGNAYKSHNDFPKAIECYEKSLIIARRAGDVVREGNAFFNLGIVYNSCSDLPKAIE 845 6899********************999999999999999999999999988887777776 PP == domain 10 score: 5.1 bits; conditional E-value: 0.04 RPN7 15 eleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerar 63 +e e+ l+ a+e k + +a+++l++ y+++ + +A+++ye+ + FUN_000362-T1 843 AIEYYEKSLNIAREAGDKAKEGNAYLNLGNAYMSHDESPKAFNCYEKSL 891 5677889999999999999999************************976 PP == domain 11 score: 11.7 bits; conditional E-value: 0.00038 RPN7 37 raledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskyle...kaksliekggdwerrnrlkvyeGlaalair 127 +a+++l+ y+ gd+++A+++ye+ + + +g + +g+ ++ +++ ++ k ++ ++gd++ nr + y G+++la + FUN_000362-T1 905 KANYNLGSVYLCRGDRSKAIECYEKSLHIAGEAGDGTTEGKAYFTLGVVYESRCDLTNAIDcyvKSLNIAREAGDRTGVNRANQYLGVSYLALG 998 789***********************99999999999999999999999998888888777333445566778999999999999999999988 PP RPN7 128 kfkeA 132 + +A FUN_000362-T1 999 DVLKA 1003 76655 PP == domain 12 score: 1.2 bits; conditional E-value: 0.64 RPN7 35 irraledlaehyakigdlenAlkayer 61 ++a+ l+ y++ d+++A+++ e+ FUN_000362-T1 1114 KAEAYFHLGAVYLSLSDFRKAIECHEK 1140 46789999***************9987 PP == domain 13 score: 13.8 bits; conditional E-value: 8.2e-05 RPN7 41 dlaehyakigdlenAlkayerarekttslghki...dlllnlirvgiffndwalvskylekaksliekggdwerrnrlkvyeGlaalairkfke 131 l+ y+ d+ +A+++ye+ ++ + +g + + ++nl v +nd+ ++ ++ ek ++ + gdw r+ + Gl + ++ +f FUN_000362-T1 1160 HLGTVYHFQSDFPKAIECYEKSLDIAREAGDRAtegSGYFNLGTVYKSRNDLPKAIEFYEKSLNIAREEGDWAREGKAYLNLGLVYDSQSDFRN 1253 6888899999***********999999998776333799999999999********************************************** PP RPN7 132 Aaklllds 139 A ++ +s FUN_000362-T1 1254 AIECYEKS 1261 *9987666 PP == domain 14 score: 10.9 bits; conditional E-value: 0.00067 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliek...ggdwerrnrlkvyeGlaalairk 128 ++ +l+ y + dl +A+++ye+ ++ +g + + +++g+ + + sk +e ++ + +gd+ ++ + G+ + ++ FUN_000362-T1 1277 GYFNLGTVYKSRNDLPKAMEFYEKSLNISREAGDRATEGKACLNLGLIYDSQSNFSKAIECYEKSLNIaweAGDQATEGKAYFSLGIVYKLHKD 1370 5678999*******************************************99999999988777666433399********************* PP RPN7 129 fkeAakllldsl 140 f++A +++ +sl FUN_000362-T1 1371 FAKAFECFEKSL 1382 ********8876 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.0 0.024 14 2 34 .. 58 90 .. 57 126 .. 0.90 2 ? -0.7 0.0 9.1 5.3e+03 4 32 .. 180 208 .. 178 216 .. 0.82 3 ? -0.3 0.0 6.8 3.9e+03 3 30 .. 219 246 .. 217 252 .. 0.85 4 ? 5.0 0.0 0.12 72 2 33 .. 258 289 .. 257 301 .. 0.83 5 ? 1.4 0.0 1.9 1.1e+03 6 32 .. 342 368 .. 338 375 .. 0.83 6 ? 0.2 0.0 4.5 2.6e+03 3 31 .. 419 447 .. 418 461 .. 0.84 7 ? 2.0 0.0 1.2 6.7e+02 2 31 .. 498 527 .. 497 533 .. 0.89 8 ? 3.6 0.0 0.36 2.1e+02 3 30 .. 539 566 .. 537 580 .. 0.86 9 ? 2.6 0.0 0.76 4.4e+02 6 30 .. 749 773 .. 745 779 .. 0.84 10 ? 6.0 0.0 0.062 36 4 28 .. 787 811 .. 785 820 .. 0.90 11 ? -0.3 0.0 6.8 3.9e+03 6 28 .. 829 851 .. 825 858 .. 0.81 12 ? 1.5 0.0 1.7 9.9e+02 2 29 .. 865 892 .. 864 901 .. 0.88 13 ? 5.9 0.0 0.064 37 5 29 .. 908 932 .. 905 940 .. 0.85 14 ? 2.4 0.0 0.92 5.3e+02 2 28 .. 1116 1142 .. 1115 1148 .. 0.89 15 ? 0.7 0.0 3.2 1.9e+03 6 30 .. 1160 1184 .. 1156 1192 .. 0.83 16 ? 2.5 0.0 0.8 4.6e+02 5 34 .. 1199 1228 .. 1196 1239 .. 0.78 17 ? 0.5 0.0 3.6 2.1e+03 3 28 .. 1237 1262 .. 1231 1270 .. 0.85 18 ? 1.3 0.0 2 1.1e+03 5 28 .. 1279 1302 .. 1276 1311 .. 0.86 19 ? 0.3 0.0 4.4 2.5e+03 6 30 .. 1320 1344 .. 1316 1350 .. 0.81 20 ? 0.8 0.0 2.9 1.7e+03 3 29 .. 1357 1383 .. 1355 1392 .. 0.85 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.024 TPR_14 2 eawlalarallalGdpdeAlelleralaldPdd 34 +a+l l+r++ + d+ +A+e++e+ l+ + FUN_000362-T1 58 DAYLNLGRVYDSQSDFPKAIECYEESLKIAKEA 90 6899**********************9987664 PP == domain 2 score: -0.7 bits; conditional E-value: 9.1 TPR_14 4 wlalarallalGdpdeAlelleralaldP 32 +l +r++ ++ +A++ +++ l+ FUN_000362-T1 180 YLKVGRVYDSESNFPKAIKFYKKSLKIAK 208 56778888999999********9999765 PP == domain 3 score: -0.3 bits; conditional E-value: 6.8 TPR_14 3 awlalarallalGdpdeAlelleralal 30 a+l l+r++ l ++ + +e++e+ l FUN_000362-T1 219 AYLSLGRVYDTLSNFPKSIECYEKSLTI 246 899999***********99999998875 PP == domain 4 score: 5.0 bits; conditional E-value: 0.12 TPR_14 2 eawlalarallalGdpdeAlelleralaldPd 33 +a+l l+ ++ + d+ +A+e++e+ l+ + FUN_000362-T1 258 DAYLNLGLVYDSQSDFPKAIECYEKSLKIARE 289 68999********************9997655 PP == domain 5 score: 1.4 bits; conditional E-value: 1.9 TPR_14 6 alarallalGdpdeAlelleralaldP 32 l+ ++ + d+ +A+e++e+ l+ FUN_000362-T1 342 NLGLVYDSQSDFPKAVECYEKSLKIAK 368 6788999999***********999765 PP == domain 6 score: 0.2 bits; conditional E-value: 4.5 TPR_14 3 awlalarallalGdpdeAlelleralald 31 a+l l+ +++ + ++ + +e++e+ l+ FUN_000362-T1 419 AYLNLGLVYFSQSNFPKSIECYEETLKIV 447 78999******************999865 PP == domain 7 score: 2.0 bits; conditional E-value: 1.2 TPR_14 2 eawlalarallalGdpdeAlelleralald 31 +a+l l+r+++ + d+ +A+e++e+ l+ FUN_000362-T1 498 DAYLNLGRVYFSQSDFCKAIECYEESLKIA 527 68999********************99865 PP == domain 8 score: 3.6 bits; conditional E-value: 0.36 TPR_14 3 awlalarallalGdpdeAlelleralal 30 a+l + ++ +Gd+ A+e++e+ l+ FUN_000362-T1 539 AYLNVGLFFYSQGDFPIAIECYEKSLKI 566 77788889999*************9986 PP == domain 9 score: 2.6 bits; conditional E-value: 0.76 TPR_14 6 alarallalGdpdeAlelleralal 30 l+ ++ + ++ +A++++e+al FUN_000362-T1 749 NLGVVYYSRSEFRKAIKCYEKALNI 773 6788899999************976 PP == domain 10 score: 6.0 bits; conditional E-value: 0.062 TPR_14 4 wlalarallalGdpdeAlelleral 28 +l l++a+ +d+ +A+e++e+ l FUN_000362-T1 787 YLKLGNAYKSHNDFPKAIECYEKSL 811 899******************9865 PP == domain 11 score: -0.3 bits; conditional E-value: 6.8 TPR_14 6 alarallalGdpdeAlelleral 28 l+ ++ + d+ +A+e++e+ l FUN_000362-T1 829 NLGIVYNSCSDLPKAIEYYEKSL 851 577788889999********976 PP == domain 12 score: 1.5 bits; conditional E-value: 1.7 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a+l l++a++ ++ +A ++e+ l FUN_000362-T1 865 NAYLNLGNAYMSHDESPKAFNCYEKSLN 892 68999******************99775 PP == domain 13 score: 5.9 bits; conditional E-value: 0.064 TPR_14 5 lalarallalGdpdeAlellerala 29 + l+ ++l +Gd ++A+e++e+ l FUN_000362-T1 908 YNLGSVYLCRGDRSKAIECYEKSLH 932 67999****************9876 PP == domain 14 score: 2.4 bits; conditional E-value: 0.92 TPR_14 2 eawlalarallalGdpdeAlelleral 28 ea+ l++++l l d+ +A+e+ e++l FUN_000362-T1 1116 EAYFHLGAVYLSLSDFRKAIECHEKGL 1142 79999****************999887 PP == domain 15 score: 0.7 bits; conditional E-value: 3.2 TPR_14 6 alarallalGdpdeAlelleralal 30 l+ ++ + d+ +A+e++e+ l FUN_000362-T1 1160 HLGTVYHFQSDFPKAIECYEKSLDI 1184 5788999999**********98875 PP == domain 16 score: 2.5 bits; conditional E-value: 0.8 TPR_14 5 lalarallalGdpdeAlelleralaldPdd 34 l+ ++ ++d+ +A+e +e+ l ++ FUN_000362-T1 1199 FNLGTVYKSRNDLPKAIEFYEKSLNIAREE 1228 568899***************998876555 PP == domain 17 score: 0.5 bits; conditional E-value: 3.6 TPR_14 3 awlalarallalGdpdeAlelleral 28 a+l l+ ++ + d+ A+e++e+ l FUN_000362-T1 1237 AYLNLGLVYDSQSDFRNAIECYEKSL 1262 78889999999999999999999865 PP == domain 18 score: 1.3 bits; conditional E-value: 2 TPR_14 5 lalarallalGdpdeAlelleral 28 l+ ++ ++d+ +A+e +e+ l FUN_000362-T1 1279 FNLGTVYKSRNDLPKAMEFYEKSL 1302 568899***************977 PP == domain 19 score: 0.3 bits; conditional E-value: 4.4 TPR_14 6 alarallalGdpdeAlelleralal 30 l+ ++ + ++++A+e++e+ l FUN_000362-T1 1320 NLGLIYDSQSNFSKAIECYEKSLNI 1344 57888899999*********98765 PP == domain 20 score: 0.8 bits; conditional E-value: 2.9 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+ l+ ++ +d+++A e++e+ l FUN_000362-T1 1357 AYFSLGIVYKLHKDFAKAFECFEKSLN 1383 6788999999************99775 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.011 6.3 206 249 .. 38 81 .. 33 91 .. 0.69 2 ! 11.1 0.0 0.00027 0.15 83 142 .. 63 123 .. 52 129 .. 0.87 3 ! 6.7 0.0 0.0057 3.3 212 251 .. 160 203 .. 134 210 .. 0.75 4 ! 12.1 0.0 0.00013 0.074 83 142 .. 223 283 .. 212 294 .. 0.90 5 ? 3.9 0.0 0.04 23 206 251 .. 318 363 .. 315 371 .. 0.67 6 ? 3.7 0.1 0.045 26 87 142 .. 467 523 .. 430 529 .. 0.58 7 ? 5.7 0.1 0.011 6.5 205 292 .. 764 850 .. 739 862 .. 0.65 8 ! 11.5 0.3 0.0002 0.12 80 251 .. 787 970 .. 771 975 .. 0.81 9 ! 13.1 0.0 6.3e-05 0.037 187 250 .. 1113 1180 .. 1091 1182 .. 0.84 10 ! 8.5 0.0 0.0016 0.94 205 251 .. 1175 1221 .. 1174 1227 .. 0.85 11 ? 2.2 0.2 0.13 78 205 251 .. 1335 1381 .. 1324 1388 .. 0.89 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.011 TPR_IF140-IFT172 206 lCyledlekaaelanetgdkaacyhlarqyenadeikeaihfft 249 Cy + l+ a+e + + + a + l+r y+++ ++ +ai+ + FUN_000362-T1 38 ECYEKSLKIASEGGDRATEGDAYLNLGRVYDSQSDFPKAIECYE 81 45555555555555555555588999999999999999998775 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00027 TPR_IF140-IFT172 83 sckrydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 + yd +++ +a + ++++l++a++ dr++ k+y+n + +++ d++++i+ yeks FUN_000362-T1 63 LGRVYDSQSDFPKAIECYEESLKIAKEAgDRVRKGKAYFNLGLVFDSQSDFSKSIECYEKS 123 556799999999999999******98754*******************************8 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0057 TPR_IF140-IFT172 212 lekaaelanetgdka....acyhlarqyenadeikeaihfftra 251 +ek+ ++a+e+gd+a + ++r y+++ ++ +ai+f+ ++ FUN_000362-T1 160 YEKSLKIAREAGDRAlegvGYLKVGRVYDSESNFPKAIKFYKKS 203 57888999999999944434689******************885 PP == domain 4 score: 12.1 bits; conditional E-value: 0.00013 TPR_IF140-IFT172 83 sckrydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeks 142 + yd l+++ ++ + ++k+l++a++ dr+ ++y n + +++ d+ +ai+ yeks FUN_000362-T1 223 LGRVYDTLSNFPKSIECYEKSLTIAKEAgDRVTEGDAYLNLGLVYDSQSDFPKAIECYEKS 283 5678*********************8754*******************************8 PP == domain 5 score: 3.9 bits; conditional E-value: 0.04 TPR_IF140-IFT172 206 lCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 Cy + l a+e + + + a++ l+ y+++ ++ +a++ + ++ FUN_000362-T1 318 ECYEKSLRIASEGGDRATEGDAFFNLGLVYDSQSDFPKAVECYEKS 363 4555555555555555555558888888888888888888887664 PP == domain 6 score: 3.7 bits; conditional E-value: 0.045 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 y+ +++ ++ + ++k+l++a++ +dr ++y n ++ ++ d+ +ai+ ye+s FUN_000362-T1 467 YNSQSEFPKSIECFEKSLKTASEgRDRATEGDAYLNLGRVYFSQSDFCKAIECYEES 523 333333333344445555555332567777777777777777777777777777765 PP == domain 7 score: 5.7 bits; conditional E-value: 0.011 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftraqaygn.airlckeheledqllnlallakk.eekleaaryfekk 292 ++Cy + l+ +e+ +++ + + + l+ y +++++ +ai+ + ++ + a +++e + ++nl+++ ++ ++ +a +y+ek+ FUN_000362-T1 764 IKCYEKALNIFTEVGEQALEGDSYLKLGNAYKSHNDFPKAIECYEKSLIIARrAGDVVRE---GNAFFNLGIVYNScSDLPKAIEYYEKS 850 567777777777777777777778888888888888888888777654332212223333...334555555444312333444555554 PP == domain 8 score: 11.5 bits; conditional E-value: 0.0002 TPR_IF140-IFT172 80 llksckrydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaL...esyvkksk 168 lk + y n++ +a + ++k+l +a++ d ++ ++++n + ++ d+ +ai++yeks e + ++ L ++y+++ + FUN_000362-T1 787 YLKLGNAYKSHNDFPKAIECYEKSLIIARRAgDVVREGNAFFNLGIVYNSCSDLPKAIEYYEKSLNIAREAGDKAKEGNAYLnlgNAYMSHDE 879 556667788889999999999999999986537888999*************************99999999999998888733448999999 PP TPR_IF140-IFT172 169 dkelkkWwaqylestgel....etalkyyeaaedylsl....vrvlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 +++ + + l+ + e + + y+ yl + Cy + l+ a e + t + a + l+ ye+ ++ +ai+ + ++ FUN_000362-T1 880 SPKAFNCYEKSLNIAREAgdraTEGKANYNLGSVYLCRgdrsKAIECYEKSLHIAGEAGDGTTEGKAYFTLGVVYESRCDLTNAIDCYVKS 970 9999999999887666542111445668999998987522213589****************************************99875 PP == domain 9 score: 13.1 bits; conditional E-value: 6.3e-05 TPR_IF140-IFT172 187 etalkyyeaaedylslv..r..vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 +a+ y++ + ylsl r + C+ + l+ a+e+ + t + a +hl+ y + ++ +ai+ + + FUN_000362-T1 1113 TKAEAYFHLGAVYLSLSdfRkaIECHEKGLNIAREVGDRTTEGKASFHLGTVYHFQSDFPKAIECYEK 1180 467888888899999863323489999*************************************9987 PP == domain 10 score: 8.5 bits; conditional E-value: 0.0016 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy + l+ a+e + + + + + l+ y + +++ +ai+f+ ++ FUN_000362-T1 1175 IECYEKSLDIAREAGDRATEGSGYFNLGTVYKSRNDLPKAIEFYEKS 1221 57888888888888888888888999999999999999999999875 PP == domain 11 score: 2.2 bits; conditional E-value: 0.13 TPR_IF140-IFT172 205 vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftra 251 + Cy + l+ a e +++ + a + l+ y ++++ +a + f ++ FUN_000362-T1 1335 IECYEKSLNIAWEAGDQATEGKAYFSLGIVYKLHKDFAKAFECFEKS 1381 7899999999999999999999*****************99999875 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.067 39 12 74 .. 31 93 .. 26 95 .. 0.81 2 ? -0.8 0.0 4.1 2.4e+03 40 74 .. 139 173 .. 99 175 .. 0.75 3 ? -0.2 0.0 2.6 1.5e+03 40 75 .. 219 254 .. 190 256 .. 0.86 4 ? 2.6 0.0 0.36 2.1e+02 40 74 .. 259 293 .. 231 298 .. 0.85 5 ? 1.7 0.0 0.68 4e+02 13 73 .. 352 412 .. 345 416 .. 0.74 6 ? 2.8 0.0 0.3 1.8e+02 39 74 .. 418 453 .. 389 459 .. 0.79 7 ? 4.5 0.0 0.092 53 12 73 .. 471 532 .. 465 546 .. 0.81 8 ? 1.3 0.0 0.9 5.2e+02 43 83 .. 582 622 .. 578 626 .. 0.74 9 ? 3.8 0.0 0.15 87 39 75 .. 825 861 .. 786 862 .. 0.83 10 ? 4.1 0.0 0.12 67 28 76 .. 854 902 .. 837 910 .. 0.75 11 ? 2.5 0.0 0.37 2.1e+02 55 84 .. 961 990 .. 944 992 .. 0.82 12 ? 3.2 0.0 0.23 1.3e+02 40 76 .. 1117 1153 .. 1105 1168 .. 0.89 13 ? 7.2 0.0 0.013 7.5 10 73 .. 1167 1230 .. 1159 1233 .. 0.93 14 ? -1.2 0.0 5.5 3.2e+03 41 76 .. 1278 1313 .. 1247 1325 .. 0.77 15 ? 3.0 0.0 0.27 1.6e+02 18 76 .. 1295 1353 .. 1278 1355 .. 0.78 16 ! 12.7 0.1 0.00024 0.14 11 85 .. 1328 1402 .. 1323 1404 .. 0.89 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.067 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDt 74 +d+++++++ + ++++ ++ + a lnl ++ + ++ +A++ ee+ k+A+e +D FUN_000362-T1 31 SDFSKSIECYEKSLKIASEGGDRATEGDAYLNLGRVYDSQSDFPKAIECYEESLKIAKEAGDR 93 56666666666666666666677777778999999999999*******************996 PP == domain 2 score: -0.8 bits; conditional E-value: 4.1 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDt 74 a lnl ++ + ++ ++ ++ e + k+Are +D FUN_000362-T1 139 AYLNLRRVYESQSDFAKPIQFYEKSLKIAREAGDR 173 56677777777777777778888889999999987 PP == domain 3 score: -0.2 bits; conditional E-value: 2.6 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDta 75 a l+l ++ ++++ ++++ e + ++A+e +D + FUN_000362-T1 219 AYLSLGRVYDTLSNFPKSIECYEKSLTIAKEAGDRV 254 789999999999999999999**********99976 PP == domain 4 score: 2.6 bits; conditional E-value: 0.36 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDt 74 a lnl ++ + ++ +A++ e + k+Are +D FUN_000362-T1 259 AYLNLGLVYDSQSDFPKAIECYEKSLKIAREAGDR 293 7899999999999999****************996 PP == domain 5 score: 1.7 bits; conditional E-value: 0.68 ANAPC5 13 dYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 d+++a+++ + ++ + +++ a lnl l+ + ++ +A++ e + ++Are +D FUN_000362-T1 352 DFPKAVECYEKSLKIAKEAGDRTLEGDAYLNLGCLYNSESDFPKAIECDEKSLNIAREAGD 412 5666666666666666666666555668899999999999999999999999999999988 PP == domain 6 score: 2.8 bits; conditional E-value: 0.3 ANAPC5 39 yallnlailhadfghneeAvkaieeaiklArenkDt 74 a lnl ++ + ++ ++++ ee+ k++re +D FUN_000362-T1 418 KAYLNLGLVYFSQSNFPKSIECYEETLKIVREAGDR 453 57888888888889999999999*********9996 PP == domain 7 score: 4.5 bits; conditional E-value: 0.092 ANAPC5 12 kdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 +++++++++ + +++ +++ + a lnl ++ + ++ +A++ ee+ k+Are ++ FUN_000362-T1 471 SEFPKSIECFEKSLKTASEGRDRATEGDAYLNLGRVYFSQSDFCKAIECYEESLKIAREAGN 532 56666666666666666666777777778999999999999999***************765 PP == domain 8 score: 1.3 bits; conditional E-value: 0.9 ANAPC5 43 nlailhadfghneeAvkaieeaiklArenkDtacLnlalsw 83 nl ++++ ++ + ++ e++ ++A+e +D+a ++ ++ + FUN_000362-T1 582 NLGHVYYSQSDFRKETECCENSLSIAKEAGDQAGVTRVNEF 622 555555555566666777899************99877665 PP == domain 9 score: 3.8 bits; conditional E-value: 0.15 ANAPC5 39 yallnlailhadfghneeAvkaieeaiklArenkDta 75 a +nl i++ + ++ +A++ e + ++Are +D+a FUN_000362-T1 825 NAFFNLGIVYNSCSDLPKAIEYYEKSLNIAREAGDKA 861 58899999***************************86 PP == domain 10 score: 4.1 bits; conditional E-value: 0.12 ANAPC5 28 tlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 + + ++ + a lnl +++ ++ +A + e + ++Are +D a+ FUN_000362-T1 854 AREAGDKAKEGNAYLNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRAT 902 5555555555568889998899999999999999999999999999875 PP == domain 11 score: 2.5 bits; conditional E-value: 0.37 ANAPC5 55 eeAvkaieeaiklArenkDtacLnlalswl 84 +A++ + ++Are +D + +n a+++l FUN_000362-T1 961 TNAIDCYVKSLNIAREAGDRTGVNRANQYL 990 57888888899************9988765 PP == domain 12 score: 3.2 bits; conditional E-value: 0.23 ANAPC5 40 allnlailhadfghneeAvkaieeaiklArenkDtac 76 a ++l ++ ++++ +A++ e ++Are +D ++ FUN_000362-T1 1117 AYFHLGAVYLSLSDFRKAIECHEKGLNIAREVGDRTT 1153 7899999999***********************9875 PP == domain 13 score: 7.2 bits; conditional E-value: 0.013 ANAPC5 10 rakdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkD 73 ++d+++a+++ + D++ + ++ + +nl +++ + ++ +A++ e + ++Are++D FUN_000362-T1 1167 FQSDFPKAIECYEKSLDIAREAGDRATEGSGYFNLGTVYKSRNDLPKAIEFYEKSLNIAREEGD 1230 5789**********************************************************99 PP == domain 14 score: -1.2 bits; conditional E-value: 5.5 ANAPC5 41 llnlailhadfghneeAvkaieeaiklArenkDtac 76 +nl +++ + ++ +A++ e + ++ re +D a+ FUN_000362-T1 1278 YFNLGTVYKSRNDLPKAMEFYEKSLNISREAGDRAT 1313 5778888888888889999999999999*9999764 PP == domain 15 score: 3.0 bits; conditional E-value: 0.27 ANAPC5 18 ldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtac 76 ++ + ++ + ++ + a+lnl ++ + ++ +A++ e + ++A e +D+a+ FUN_000362-T1 1295 MEFYEKSLNISREAGDRATEGKACLNLGLIYDSQSNFSKAIECYEKSLNIAWEAGDQAT 1353 5555555555555555556667999999999999********************99975 PP == domain 16 score: 12.7 bits; conditional E-value: 0.00024 ANAPC5 11 akdYqsaldsLhryFDytlssneessyqyallnlailhadfghneeAvkaieeaiklArenkDtacLnlalswll 85 ++++++a+++ + ++ + ++ + a ++l i++ ++ ++A + +e + ++Are +D+a ++ a+++l+ FUN_000362-T1 1328 QSNFSKAIECYEKSLNIAWEAGDQATEGKAYFSLGIVYKLHKDFAKAFECFEKSLNIAREAGDHAGVSRANQYLA 1402 5788888888888888888888888888999************************************99988876 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.5 2.9e+02 33 62 .. 61 90 .. 26 95 .. 0.61 2 ? 3.9 0.0 0.13 75 3 54 .. 65 122 .. 63 135 .. 0.60 3 ? 5.6 0.0 0.039 23 5 65 .. 267 333 .. 263 335 .. 0.78 4 ? 5.5 0.0 0.041 24 5 60 .. 347 401 .. 343 416 .. 0.85 5 ? 2.2 0.0 0.46 2.7e+02 5 65 .. 387 453 .. 383 456 .. 0.73 6 ? 2.3 0.0 0.42 2.5e+02 5 66 .. 427 494 .. 423 495 .. 0.71 7 ? 5.7 0.0 0.038 22 3 64 .. 505 572 .. 503 575 .. 0.77 8 ? 1.3 0.0 0.85 5e+02 32 56 .. 747 771 .. 744 782 .. 0.83 9 ? 5.2 0.0 0.051 30 1 32 [. 790 821 .. 790 861 .. 0.61 10 ? 5.3 0.0 0.048 28 1 64 [. 870 939 .. 870 942 .. 0.83 11 ? 2.3 0.1 0.41 2.4e+02 30 57 .. 1109 1136 .. 1106 1148 .. 0.82 12 ? 6.4 0.0 0.021 12 4 57 .. 1164 1216 .. 1161 1228 .. 0.88 13 ? 2.8 0.0 0.29 1.7e+02 5 56 .. 1245 1295 .. 1241 1313 .. 0.67 14 ? 1.7 0.0 0.65 3.8e+02 31 58 .. 1317 1344 .. 1281 1354 .. 0.63 15 ? 3.1 0.0 0.24 1.4e+02 3 64 .. 1323 1390 .. 1321 1397 .. 0.77 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.5 TPR_9 33 rdrGllyaqlgcleaAladLeaylalapda 62 + G++y + ++ +A+++ e l++a +a FUN_000362-T1 61 LNLGRVYDSQSDFPKAIECYEESLKIAKEA 90 555666666666666666666655555555 PP == domain 2 score: 3.9 bits; conditional E-value: 0.13 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLea 54 + y ++ d+++a++++e l + + + +++ Gl+ + ++++++++ e+ FUN_000362-T1 65 RVYDSQSDFPKAIECYEESLKIakeagdRVRKGKAYFNLGLVFDSQSDFSKSIECYEK 122 56778999*********99999333222222233444455555555555555555555 PP == domain 3 score: 5.6 bits; conditional E-value: 0.039 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 y ++ d+++a++++e l + + ++ + + Gl+y +g + +++++ e+ l++a ++ d+ FUN_000362-T1 267 YDSQSDFPKAIECYEKSLKIareagdRVREGKAYLNLGLVYGSQGIFGKSIECYEKSLRIASEGGDR 333 667899999*****99999967633333444457789999999999999999999999999988887 PP == domain 4 score: 5.5 bits; conditional E-value: 0.041 TPR_9 5 yireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeaylalap 60 y ++ d+++a +++e l +a +++++r G +y +lgcl + d+ ++++ ++ FUN_000362-T1 347 YDSQSDFPKAVECYEKSLKIA-KEAGDRTLEGDAYLNLGCLYNSESDFPKAIECDE 401 66799**************97.99999*************9999999988886555 PP == domain 5 score: 2.2 bits; conditional E-value: 0.46 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapda 65 y +e d+++a+++ e l + + ++ + + Gl+y+ + ++ +++++ e l++ +a d+ FUN_000362-T1 387 YNSESDFPKAIECDEKSLNIareagdPVREGKAYLNLGLVYFSQSNFPKSIECYEETLKIVREAGDR 453 6677788888888888777766544222334567789999999999999999999998877777665 PP == domain 6 score: 2.3 bits; conditional E-value: 0.42 TPR_9 5 yireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 y+++ ++++ ++++e l + + ++ +++ G++y + + ++++++e+ l+ a +++d++ FUN_000362-T1 427 YFSQSNFPKSIECYEETLKIvreagdRVREGKAYFNLGFVYNSQSEFPKSIECFEKSLKTASEGRDRA 494 66666666666666666666666333333444588999999999999999999999999999998875 PP == domain 7 score: 5.7 bits; conditional E-value: 0.038 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapd 64 + y+++ d+ +a++++e l + + + + + + Gl + +g++ A+++ e+ l++a ++ d FUN_000362-T1 505 RVYFSQSDFCKAIECYEESLKIareagnRDLEGDAYLNVGLFFYSQGDFPIAIECYEKSLKIASEGVD 572 667888888888888888888855554333345688999******************99998887765 PP == domain 8 score: 1.3 bits; conditional E-value: 0.85 TPR_9 32 rrdrGllyaqlgcleaAladLeayl 56 +++ G +y+ + + +A+++ e++l FUN_000362-T1 747 YFNLGVVYYSRSEFRKAIKCYEKAL 771 5678999999999999999999887 PP == domain 9 score: 5.2 bits; conditional E-value: 0.051 TPR_9 1 LkaiyireedleralavverllllaPddpeer 32 L ++y + +d+++a++++e l++a + + + FUN_000362-T1 790 LGNAYKSHNDFPKAIECYEKSLIIARRAGDVV 821 56889999**************9964333333 PP == domain 10 score: 5.3 bits; conditional E-value: 0.048 TPR_9 1 Lkaiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapd 64 L ++y++ +++++a +++e l + + + ++ G++y +g+ ++A+++ e+ l++a +a d FUN_000362-T1 870 LGNAYMSHDESPKAFNCYEKSLNIareagdRATEGKANYNLGSVYLCRGDRSKAIECYEKSLHIAGEAGD 939 5688999999999999999999997876666666667899999999999999999999999988887765 PP == domain 11 score: 2.3 bits; conditional E-value: 0.41 TPR_9 30 eerrdrGllyaqlgcleaAladLeayla 57 ++r ++ +y++lg++ +l d+ ++++ FUN_000362-T1 1109 GDRATKAEAYFHLGAVYLSLSDFRKAIE 1136 6788899999999999999999998886 PP == domain 12 score: 6.4 bits; conditional E-value: 0.021 TPR_9 4 iyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 y+ + d+++a++++e l +a +++++r G+ y++lg + +++ dL ++++ FUN_000362-T1 1164 VYHFQSDFPKAIECYEKSLDIA-REAGDRATEGSGYFNLGTVYKSRNDLPKAIE 1216 577789***************6.99***********************988776 PP == domain 13 score: 2.8 bits; conditional E-value: 0.29 TPR_9 5 yireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayl 56 y ++ d+ a++++e ll+a +++r G+ y++lg + +++ dL +++ FUN_000362-T1 1245 YDSQSDFRNAIECYEKSLLIAT-KAGDRAAEGSGYFNLGTVYKSRNDLPKAM 1295 6678899999999999999964.45666666666666666666666665444 PP == domain 14 score: 1.7 bits; conditional E-value: 0.65 TPR_9 31 errdrGllyaqlgcleaAladLeaylal 58 + Gl+y + ++++A+++ e+ l + FUN_000362-T1 1317 ACLNLGLIYDSQSNFSKAIECYEKSLNI 1344 4567888999999999999988876655 PP == domain 15 score: 3.1 bits; conditional E-value: 0.24 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAladLeaylalapdapd 64 iy ++ ++ +a++++e l + + + ++ G++y ++++A +++e+ l +a +a d FUN_000362-T1 1323 LIYDSQSNFSKAIECYEKSLNIaweagdQATEGKAYFSLGIVYKLHKDFAKAFECFEKSLNIAREAGD 1390 57778888888999988888887776666666667888999999999999999999998887776665 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.085 50 52 83 .. 59 90 .. 52 96 .. 0.87 2 ? -0.3 0.0 2.1 1.2e+03 53 82 .. 180 209 .. 173 215 .. 0.86 3 ? 3.0 0.0 0.2 1.2e+02 51 83 .. 218 250 .. 212 255 .. 0.88 4 ? 2.0 0.0 0.39 2.3e+02 54 82 .. 261 289 .. 253 294 .. 0.79 5 ? 5.5 0.0 0.034 20 55 155 .. 342 451 .. 331 454 .. 0.77 6 ? -2.0 0.0 6.7 3.9e+03 56 81 .. 463 488 .. 457 495 .. 0.68 7 ? 5.8 0.0 0.027 16 52 83 .. 499 530 .. 491 543 .. 0.86 8 ? -0.6 0.0 2.5 1.5e+03 59 82 .. 546 569 .. 532 576 .. 0.71 9 ? -0.0 0.0 1.7 9.7e+02 53 82 .. 787 816 .. 775 823 .. 0.83 10 ? 2.7 0.0 0.24 1.4e+02 49 83 .. 863 897 .. 858 903 .. 0.86 11 ? 1.1 0.0 0.74 4.3e+02 56 82 .. 910 936 .. 902 943 .. 0.89 12 ? -1.9 0.0 6.4 3.7e+03 53 82 .. 947 976 .. 938 980 .. 0.80 13 ? 3.3 0.0 0.16 92 49 82 .. 1114 1147 .. 1110 1154 .. 0.87 14 ? 6.0 0.0 0.024 14 56 146 .. 1161 1260 .. 1156 1263 .. 0.69 15 ? 6.6 0.0 0.015 9 53 149 .. 1238 1343 .. 1232 1351 .. 0.76 16 ? 0.5 0.0 1.2 6.9e+02 52 83 .. 1357 1388 .. 1349 1393 .. 0.81 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.085 TPR_CcmH_CycH 52 gWllLGriglslndaetAiqAfekAlklapnn 83 + l LGr++ s++d +Ai+ +e +lk+a + FUN_000362-T1 59 AYLNLGRVYDSQSDFPKAIECYEESLKIAKEA 90 5678***********************99875 PP == domain 2 score: -0.3 bits; conditional E-value: 2.1 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlklapn 82 l Gr++ s ++ +Ai+ ++k+lk+a + FUN_000362-T1 180 YLKVGRVYDSESNFPKAIKFYKKSLKIAKK 209 567899999****************99876 PP == domain 3 score: 3.0 bits; conditional E-value: 0.2 TPR_CcmH_CycH 51 tgWllLGriglslndaetAiqAfekAlklapnn 83 ++ l LGr++ l++ ++i+ +ek+l++a + FUN_000362-T1 218 KAYLSLGRVYDTLSNFPKSIECYEKSLTIAKEA 250 66789**********************999875 PP == domain 4 score: 2.0 bits; conditional E-value: 0.39 TPR_CcmH_CycH 54 llLGriglslndaetAiqAfekAlklapn 82 l LG ++ s++d +Ai+ +ek+lk+a + FUN_000362-T1 261 LNLGLVYDSQSDFPKAIECYEKSLKIARE 289 66888888999999999999999988766 PP == domain 5 score: 5.5 bits; conditional E-value: 0.034 TPR_CcmH_CycH 55 lLGriglslndaetAiqAfekAlklapnnteikls...YaqaLmlsgdeedlkkAeelLkkllkqdp......tnlralsllAfnafeqgdyeeAi 141 LG ++ s++d +A++ +ek+lk+a + + l+ Y ++ l ++e+d kA e +k l+ + ++ +a+ l++ +f+q +++++i FUN_000362-T1 342 NLGLVYDSQSDFPKAVECYEKSLKIAKEAGDRTLEgdaYLNLGCLYNSESDFPKAIECDEKSLNIAReagdpvREGKAYLNLGLVYFSQSNFPKSI 437 58999999999999**********999999998854448888888999999999987766665433211111246689999999999999999999 PP TPR_CcmH_CycH 142 aaWqkmlkllpadd 155 + +++ lk++ + FUN_000362-T1 438 ECYEETLKIVREAG 451 99999999887765 PP == domain 6 score: -2.0 bits; conditional E-value: 6.7 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklap 81 LG ++ s+++ ++i+ fek+lk a FUN_000362-T1 463 LGFVYNSQSEFPKSIECFEKSLKTAS 488 66677777777777777777777665 PP == domain 7 score: 5.8 bits; conditional E-value: 0.027 TPR_CcmH_CycH 52 gWllLGriglslndaetAiqAfekAlklapnn 83 + l LGr+++s++d +Ai+ +e +lk+a + FUN_000362-T1 499 AYLNLGRVYFSQSDFCKAIECYEESLKIAREA 530 5678***********************99875 PP == domain 8 score: -0.6 bits; conditional E-value: 2.5 TPR_CcmH_CycH 59 iglslndaetAiqAfekAlklapn 82 +s++d Ai+ +ek+lk+a + FUN_000362-T1 546 FFYSQGDFPIAIECYEKSLKIASE 569 456677777777888887777766 PP == domain 9 score: -0.0 bits; conditional E-value: 1.7 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlklapn 82 l LG + s nd +Ai+ +ek+l +a FUN_000362-T1 787 YLKLGNAYKSHNDFPKAIECYEKSLIIARR 816 5679999999*************9988765 PP == domain 10 score: 2.7 bits; conditional E-value: 0.24 TPR_CcmH_CycH 49 datgWllLGriglslndaetAiqAfekAlklapnn 83 + ++ l LG ++s + +A++ +ek+l++a + FUN_000362-T1 863 EGNAYLNLGNAYMSHDESPKAFNCYEKSLNIAREA 897 5567889***********************99875 PP == domain 11 score: 1.1 bits; conditional E-value: 0.74 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapn 82 LG ++l +d ++Ai+ +ek+l++a + FUN_000362-T1 910 LGSVYLCRGDRSKAIECYEKSLHIAGE 936 999*******************99865 PP == domain 12 score: -1.9 bits; conditional E-value: 6.4 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlklapn 82 + LG ++ s d+++Ai+ + k+l++a + FUN_000362-T1 947 YFTLGVVYESRCDLTNAIDCYVKSLNIARE 976 567888888999999999999999998765 PP == domain 13 score: 3.3 bits; conditional E-value: 0.16 TPR_CcmH_CycH 49 datgWllLGriglslndaetAiqAfekAlklapn 82 a++ + LG ++lsl+d ++Ai+ ek l++a + FUN_000362-T1 1114 KAEAYFHLGAVYLSLSDFRKAIECHEKGLNIARE 1147 5677889********************9999875 PP == domain 14 score: 6.0 bits; conditional E-value: 0.024 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteik...lsYaqaLmlsgdeedlkkAeelLkkllkqdpt......nlralsllAfnafeqgdyeeA 140 LG ++ ++d +Ai+ +ek+l++a + + + +Y ++ ++ ++++dl kA e+++k l+ ++ + +a+ l++ + +q d+++A FUN_000362-T1 1161 LGTVYHFQSDFPKAIECYEKSLDIAREAGDRAtegSGYFNLGTVYKSRNDLPKAIEFYEKSLNIAREegdwarEGKAYLNLGLVYDSQSDFRNA 1254 7888888888888999999999888776655411257888888888888888888888887764443111111346777788888888888888 PP TPR_CcmH_CycH 141 iaaWqk 146 i+ ++k FUN_000362-T1 1255 IECYEK 1260 887775 PP == domain 15 score: 6.6 bits; conditional E-value: 0.015 TPR_CcmH_CycH 53 WllLGriglslndaetAiqAfekAlklapnnteik...lsYaqaLmlsgdeedlkkAeelLkkllk......qdptnlralsllAfnafeqgdy 137 l LG ++ s++d ++Ai+ +ek+l +a + + + +Y ++ ++ ++++dl kA e+++k l+ + t+ +a l++ + +q ++ FUN_000362-T1 1238 YLNLGLVYDSQSDFRNAIECYEKSLLIATKAGDRAaegSGYFNLGTVYKSRNDLPKAMEFYEKSLNisreagDRATEGKACLNLGLIYDSQSNF 1331 5679999999999999999999999998876554412268999999999999999999999988762222223456677888889999999999 PP TPR_CcmH_CycH 138 eeAiaaWqkmlk 149 ++Ai+ ++k l+ FUN_000362-T1 1332 SKAIECYEKSLN 1343 999999888665 PP == domain 16 score: 0.5 bits; conditional E-value: 1.2 TPR_CcmH_CycH 52 gWllLGriglslndaetAiqAfekAlklapnn 83 + + LG ++ +d ++A++ fek+l++a + FUN_000362-T1 1357 AYFSLGIVYKLHKDFAKAFECFEKSLNIAREA 1388 55678889999999999********9998765 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.038 22 131 162 .. 59 90 .. 53 95 .. 0.89 2 ? 4.5 0.0 0.067 39 129 160 .. 97 128 .. 94 132 .. 0.91 3 ? 4.9 0.0 0.052 30 98 162 .. 140 210 .. 135 215 .. 0.70 4 ? 3.4 0.0 0.15 85 129 163 .. 217 251 .. 212 255 .. 0.90 5 ? 6.2 0.0 0.021 12 131 162 .. 259 290 .. 255 295 .. 0.88 6 ? 6.4 0.0 0.018 10 131 162 .. 339 370 .. 297 374 .. 0.77 7 ? 1.1 0.0 0.73 4.2e+02 129 161 .. 417 449 .. 378 455 .. 0.73 8 ? 3.8 0.0 0.11 65 97 159 .. 419 487 .. 408 495 .. 0.62 9 ? -0.2 0.0 1.8 1.1e+03 131 161 .. 499 529 .. 491 536 .. 0.87 10 ? 2.8 0.1 0.23 1.3e+02 134 159 .. 749 774 .. 741 781 .. 0.86 11 ! 8.7 0.1 0.0035 2 51 175 .. 860 990 .. 825 995 .. 0.83 12 ? 4.1 0.0 0.086 50 97 161 .. 1117 1187 .. 1103 1193 .. 0.71 13 ! 9.4 0.1 0.0021 1.2 101 156 .. 1201 1262 .. 1187 1272 .. 0.73 14 ! 10.2 0.2 0.0012 0.72 100 158 .. 1280 1344 .. 1272 1354 .. 0.72 15 ? 3.8 0.2 0.11 65 129 175 .. 1355 1401 .. 1350 1407 .. 0.88 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.038 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklskes 162 Ay lG ++++++ + +A+e+Ye++ k++ke+ FUN_000362-T1 59 AYLNLGRVYDSQSDFPKAIECYEESLKIAKEA 90 88899********************9999886 PP == domain 2 score: 4.5 bits; conditional E-value: 0.067 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklsk 160 +kAy lGl+ ++++ +++ +e+Yek+ k+++ FUN_000362-T1 97 GKAYFNLGLVFDSQSDFSKSIECYEKSLKIAS 128 69************************988875 PP == domain 3 score: 4.9 bits; conditional E-value: 0.052 ARM_TT21_C 98 wLlladiyiqsgkldlAeeLlkkvlkynksca.kAyellGl.....iaekeqsykdAaenYekAWklskes 162 +L l +y +++ + + ++ +k lk ++ + +A e +G+ ++++e+++ +A++ Y+k+ k++k++ FUN_000362-T1 140 YLNLRRVYESQSDFAKPIQFYEKSLKIAREAGdRALEGVGYlkvgrVYDSESNFPKAIKFYKKSLKIAKKA 210 566666666666666666777777777776543677765542222278****************9999876 PP == domain 4 score: 3.4 bits; conditional E-value: 0.15 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskess 163 kAy lG +++ +++ + +e+Yek+ +++ke+ FUN_000362-T1 217 IKAYLSLGRVYDTLSNFPKSIECYEKSLTIAKEAG 251 59************************999988765 PP == domain 5 score: 6.2 bits; conditional E-value: 0.021 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklskes 162 Ay lGl++++++ + +A+e+Yek+ k++ e+ FUN_000362-T1 259 AYLNLGLVYDSQSDFPKAIECYEKSLKIAREA 290 88899********************9998776 PP == domain 6 score: 6.4 bits; conditional E-value: 0.018 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklskes 162 A+ lGl++++++ + +A+e+Yek+ k++ke+ FUN_000362-T1 339 AFFNLGLVYDSQSDFPKAVECYEKSLKIAKEA 370 55579********************9998875 PP == domain 7 score: 1.1 bits; conditional E-value: 0.73 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklske 161 +kAy lGl++ +++++ + +e+Ye+ k+ e FUN_000362-T1 417 GKAYLNLGLVYFSQSNFPKSIECYEETLKIVRE 449 589999999999999999999999998877665 PP == domain 8 score: 3.8 bits; conditional E-value: 0.11 ARM_TT21_C 97 awLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsykdAaenYekAWkls 159 a+L l +y +++++ ++ e + lk ++ +kAy lG+++++++++ + +e++ek+ k++ FUN_000362-T1 419 AYLNLGLVYFSQSNFPKSIECYEETLKIVREAgdrvreGKAYFNLGFVYNSQSEFPKSIECFEKSLKTA 487 555555555555555555544444444444432222225788888888888888888888888877665 PP == domain 9 score: -0.2 bits; conditional E-value: 1.8 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklske 161 Ay lG ++ +++ + +A+e+Ye++ k++ e FUN_000362-T1 499 AYLNLGRVYFSQSDFCKAIECYEESLKIARE 529 7888999999**************9998766 PP == domain 10 score: 2.8 bits; conditional E-value: 0.23 ARM_TT21_C 134 llGliaekeqsykdAaenYekAWkls 159 lG+++ +++++++A+++YekA ++ FUN_000362-T1 749 NLGVVYYSRSEFRKAIKCYEKALNIF 774 589*******************8765 PP == domain 11 score: 8.7 bits; conditional E-value: 0.0035 ARM_TT21_C 51 ekdsvpallalaealvllkqtqkArnqLkriskleysveeadelekawLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliae 140 + ++ a+l l +a++ +++kA n ++ ++ ++ + ka l +y+ g +A e +k l+ + +kAy lG+++e FUN_000362-T1 860 KAKEGNAYLNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRATEGKANYNLGSVYLCRGDRSKAIECYEKSLHIAGEAgdgtteGKAYFTLGVVYE 955 34457789999999999999999999999998998888888888999999********************999987653333336*********** PP ARM_TT21_C 141 keqsykdAaenYekAWklskesspavGykLAfnyL 175 ++ ++A+++Y k+ +++ e+ + G A +yL FUN_000362-T1 956 SRCDLTNAIDCYVKSLNIAREAGDRTGVNRANQYL 990 ****************9999999888888887777 PP == domain 12 score: 4.1 bits; conditional E-value: 0.086 ARM_TT21_C 97 awLlladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsykdAaenYekAWklske 161 a+ l +y++ + + +A e +k l+ ++ +kA lG+++ ++ + +A+e+Yek+ +++ e FUN_000362-T1 1117 AYFHLGAVYLSLSDFRKAIECHEKGLNIAREVgdrtteGKASFHLGTVYHFQSDFPKAIECYEKSLDIARE 1187 55556666666666666666666666665554222222689999*******************99877665 PP == domain 13 score: 9.4 bits; conditional E-value: 0.0021 ARM_TT21_C 101 ladiyiqsgkldlAeeLlkkvlkynks......cakAyellGliaekeqsykdAaenYekAW 156 l +y + + l +A e+ +k l+ ++ +kAy lGl++++++ +++A+e+Yek+ FUN_000362-T1 1201 LGTVYKSRNDLPKAIEFYEKSLNIAREegdwarEGKAYLNLGLVYDSQSDFRNAIECYEKSL 1262 555666666666666666666666665222222369***********************986 PP == domain 14 score: 10.2 bits; conditional E-value: 0.0012 ARM_TT21_C 100 lladiyiqsgkldlAeeLlkkvlkynksc......akAyellGliaekeqsykdAaenYekAWkl 158 l +y + + l +A e+ +k l+ ++ +kA lGli+++++++++A+e+Yek+ ++ FUN_000362-T1 1280 NLGTVYKSRNDLPKAMEFYEKSLNISREAgdrateGKACLNLGLIYDSQSNFSKAIECYEKSLNI 1344 56667777777777888888888887776222222477778*******************96544 PP == domain 15 score: 3.8 bits; conditional E-value: 0.11 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskesspavGykLAfnyL 175 +kAy lG+++ ++ + +A e++ek+ +++ e+ + G A +yL FUN_000362-T1 1355 GKAYFSLGIVYKLHKDFAKAFECFEKSLNIAREAGDHAGVSRANQYL 1401 69***************************999998888877777776 PP >> ComR_TPR ComR tetratricopeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.4 8.3e+02 186 212 .. 27 53 .. 22 57 .. 0.84 2 ? 3.5 0.0 0.12 69 188 213 .. 69 94 .. 65 100 .. 0.89 3 ? 2.0 0.0 0.35 2e+02 185 214 .. 146 175 .. 98 180 .. 0.74 4 ? 4.3 0.1 0.066 39 145 213 .. 147 214 .. 138 219 .. 0.62 5 ? 4.4 0.0 0.061 35 145 212 .. 187 253 .. 178 258 .. 0.62 6 ? 4.5 0.0 0.059 34 144 213 .. 226 294 .. 217 298 .. 0.62 7 ? 5.1 0.0 0.038 22 188 215 .. 349 376 .. 342 380 .. 0.90 8 ? 2.9 0.0 0.17 1e+02 143 214 .. 465 535 .. 457 538 .. 0.66 9 ? 5.4 0.0 0.03 18 185 213 .. 793 821 .. 745 825 .. 0.69 10 ? 0.6 0.0 0.9 5.2e+02 190 212 .. 838 860 .. 827 865 .. 0.89 11 ? 1.2 0.0 0.61 3.5e+02 139 211 .. 868 939 .. 863 943 .. 0.66 12 ? 5.3 0.0 0.033 19 140 212 .. 1120 1191 .. 1104 1195 .. 0.69 13 ? 2.8 0.0 0.19 1.1e+02 186 212 .. 1245 1271 .. 1198 1275 .. 0.61 14 ? 2.8 0.1 0.19 1.1e+02 148 211 .. 1288 1350 .. 1278 1357 .. 0.51 15 ? 2.6 0.1 0.22 1.3e+02 151 211 .. 1328 1390 .. 1313 1396 .. 0.46 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.4 ComR_TPR 186 lkvkkdfkkAkelYqkaimfakllgde 212 + k df+k e+Y+k++ a+ gd FUN_000362-T1 27 IASKSDFSKSIECYEKSLKIASEGGDR 53 67799**************99887775 PP == domain 2 score: 3.5 bits; conditional E-value: 0.12 ComR_TPR 188 vkkdfkkAkelYqkaimfakllgdev 213 + df kA e+Y++++ ak gd v FUN_000362-T1 69 SQSDFPKAIECYEESLKIAKEAGDRV 94 5789*****************99986 PP == domain 3 score: 2.0 bits; conditional E-value: 0.35 ComR_TPR 185 ylkvkkdfkkAkelYqkaimfakllgdevL 214 + + + df+k ++Y+k++ a+ gd +L FUN_000362-T1 146 VYESQSDFAKPIQFYEKSLKIAREAGDRAL 175 344688999999999999999999999887 PP == domain 4 score: 4.3 bits; conditional E-value: 0.066 ComR_TPR 145 llllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 +++ d+ k ++ +++ +i +++ d v l+ + + + +f kA ++Y k++ ak gd v FUN_000362-T1 147 YESQSDFAKPIQFYEKSLKIAREAGDRA-LEGVGYLKVGRVYDSESNFPKAIKFYKKSLKIAKKAGDRV 214 5555555555555555555555555443.3334444444455678899999999999999999888875 PP == domain 5 score: 4.4 bits; conditional E-value: 0.061 ComR_TPR 145 llllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgde 212 + + ++ k ++ k++ +i +k+ d + + +++ + y +f k e+Y+k+++ ak gd FUN_000362-T1 187 YDSESNFPKAIKFYKKSLKIAKKAGDRVREIKAYLSLGRVYD-TLSNFPKSIECYEKSLTIAKEAGDR 253 555555566666666666666666666665555555555554.5567777777777777777777775 PP == domain 6 score: 4.5 bits; conditional E-value: 0.059 ComR_TPR 144 vllllkdyekleellkvlkeiidktqdf.qkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdev 213 v+ +l ++ k e+ +++ +i +++ d ++ +l l y + + df kA e+Y+k++ a+ gd v FUN_000362-T1 226 VYDTLSNFPKSIECYEKSLTIAKEAGDRvTEGDAYLNLGLVY--DSQSDFPKAIECYEKSLKIAREAGDRV 294 555555555555555555555555544313333444444444..448999999999999999999998875 PP == domain 7 score: 5.1 bits; conditional E-value: 0.038 ComR_TPR 188 vkkdfkkAkelYqkaimfakllgdevLa 215 + df kA e+Y+k++ ak gd L+ FUN_000362-T1 349 SQSDFPKAVECYEKSLKIAKEAGDRTLE 376 5789********************9986 PP == domain 8 score: 2.9 bits; conditional E-value: 0.17 ComR_TPR 143 avllllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgdevL 214 +v+ + ++ k e+ +++ ++ ++ +d +++ + y + df kA e+Y++++ a+ g+ L FUN_000362-T1 465 FVYNSQSEFPKSIECFEKSLKTASEGRDRATEGDAYLNLGRVYF-SQSDFCKAIECYEESLKIAREAGNRDL 535 55555556666666666666666666665554444444444444.599****************99998766 PP == domain 9 score: 5.4 bits; conditional E-value: 0.03 ComR_TPR 185 ylkvkkdfkkAkelYqkaimfakllgdev 213 + k ++df kA e+Y+k++ a+ gd v FUN_000362-T1 793 AYKSHNDFPKAIECYEKSLIIARRAGDVV 821 445689****************9999975 PP == domain 10 score: 0.6 bits; conditional E-value: 0.9 ComR_TPR 190 kdfkkAkelYqkaimfakllgde 212 d+ kA e+Y+k++ a+ gd+ FUN_000362-T1 838 SDLPKAIEYYEKSLNIAREAGDK 860 6889**************99997 PP == domain 11 score: 1.2 bits; conditional E-value: 0.61 ComR_TPR 139 lsalavllllkdyekleellkvlkeiidktqdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 l++ +++++++ k ++ +++ +i +++ d + yl d +kA e+Y+k++ a gd FUN_000362-T1 868 LNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRATEGKANYNLGSVYL-CRGDRSKAIECYEKSLHIAGEAGD 939 555566666666667777777777777766665555544444444455.688999999999999988876666 PP == domain 12 score: 5.3 bits; conditional E-value: 0.033 ComR_TPR 140 salavllllkdyekleellkvlkeiidktqdfqkkp.ivlmlewkyylkvkkdfkkAkelYqkaimfakllgde 212 ++ av+l+l d++k e+ ++ +i ++ d + + l y+ + df kA e+Y+k++ a+ gd FUN_000362-T1 1120 HLGAVYLSLSDFRKAIECHEKGLNIAREVGDRTTEGkASFHLGTVYH--FQSDFPKAIECYEKSLDIAREAGDR 1191 55566666666666666666666666666555443303344444444..59*****************999986 PP == domain 13 score: 2.8 bits; conditional E-value: 0.19 ComR_TPR 186 lkvkkdfkkAkelYqkaimfakllgde 212 + + df++A e+Y+k+++ a gd FUN_000362-T1 1245 YDSQSDFRNAIECYEKSLLIATKAGDR 1271 345778888888888888888877775 PP == domain 14 score: 2.8 bits; conditional E-value: 0.19 ComR_TPR 148 lkdyekleellkvlkeiidktqdfqkkp.ivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 +d k e+ +++ +i +++ d +l l + + + +f+kA e+Y+k++ a gd FUN_000362-T1 1288 RNDLPKAMEFYEKSLNISREAGDRATEGkACLNLG--LIYDSQSNFSKAIECYEKSLNIAWEAGD 1350 44444444444444444444443322220222222..2233467777777777777777766666 PP == domain 15 score: 2.6 bits; conditional E-value: 0.22 ComR_TPR 151 yekleellkvlkeiidkt....qdfqkkpivlmlewkyylkvkkdfkkAkelYqkaimfakllgd 211 +++ +++++ ++ ++ + ++++ ++ l y k++kdf+kA e+++k++ a+ gd FUN_000362-T1 1328 QSNFSKAIECYEKSLNIAweagDQATEGKAYFSLGIVY--KLHKDFAKAFECFEKSLNIAREAGD 1390 33333333333333222200001122222333333333..3366666666666666666666555 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 5.5 3.2e+03 38 70 .. 55 84 .. 29 93 .. 0.59 2 ? 0.4 0.0 1.7 1e+03 12 76 .. 103 170 .. 93 174 .. 0.62 3 ? 0.5 0.0 1.6 9.3e+02 15 46 .. 185 217 .. 180 254 .. 0.61 4 ? -0.9 0.0 4.3 2.5e+03 39 75 .. 256 289 .. 225 293 .. 0.72 5 ? -0.6 0.0 3.4 2e+03 13 41 .. 264 292 .. 254 330 .. 0.61 6 ? 0.7 0.0 1.4 8e+02 38 67 .. 335 364 .. 298 373 .. 0.74 7 ! 11.7 0.0 0.00052 0.3 16 79 .. 347 413 .. 339 414 .. 0.76 8 ? 1.5 0.0 0.75 4.4e+02 11 68 .. 422 485 .. 416 495 .. 0.69 9 ? -1.2 0.0 5.3 3.1e+03 36 71 .. 493 525 .. 466 532 .. 0.63 10 ? 2.0 0.0 0.52 3e+02 12 67 .. 543 604 .. 538 613 .. 0.73 11 ? 2.0 0.0 0.53 3.1e+02 15 64 .. 753 808 .. 747 820 .. 0.69 12 ? 4.1 0.0 0.12 68 20 77 .. 798 858 .. 792 861 .. 0.71 13 ? -2.1 0.0 9.9 5.8e+03 40 76 .. 944 977 .. 917 980 .. 0.62 14 ? 1.6 0.0 0.72 4.2e+02 50 78 .. 1125 1150 .. 1109 1152 .. 0.77 15 ? 1.4 0.0 0.85 4.9e+02 40 75 .. 1196 1227 .. 1159 1231 .. 0.72 16 ? 1.9 0.0 0.57 3.3e+02 21 77 .. 1250 1309 .. 1234 1312 .. 0.62 17 ? 4.6 0.0 0.086 50 13 75 .. 1322 1387 .. 1311 1391 .. 0.68 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 5.5 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaql 70 +d + lG ++ + s++ k e e l FUN_000362-T1 55 TEGDAYLNLGRVYDSQSDFPKAIECYEE---SL 84 3467788899999999888775544443...33 PP == domain 2 score: 0.4 bits; conditional E-value: 1.7 Rapsyn_N 12 kGlklyesndtekalrvWrkvlkktsdred......kfrllGylitahsemGkykealefslaqlniaeel 76 Gl + + d k++ + k lk +s+ +d + l ++++ s+ + ++f + l ia+e FUN_000362-T1 103 LGLVFDSQSDFSKSIECYEKSLKIASEGGDwategdAYLNLRRVYESQSD---FAKPIQFYEKSLKIAREA 170 56777778888888888888888877654411100044444455555554...555788888888888885 PP == domain 3 score: 0.5 bits; conditional E-value: 1.6 Rapsyn_N 15 klyesn.dtekalrvWrkvlkktsdredkfrll 46 ++y+s+ + ka++ ++k lk + + +d+ r + FUN_000362-T1 185 RVYDSEsNFPKAIKFYKKSLKIAKKAGDRVREI 217 66776426689*******999998888887633 PP == domain 4 score: -0.9 bits; conditional E-value: 4.3 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaee 75 +d + lG ++ + s++ k e + l ia+e FUN_000362-T1 256 EGDAYLNLGLVYDSQSDFPKAIECY---EKSLKIARE 289 5677778888888888877654444...444455555 PP == domain 5 score: -0.6 bits; conditional E-value: 3.4 Rapsyn_N 13 GlklyesndtekalrvWrkvlkktsdred 41 Gl + d ka+ + k lk + + +d FUN_000362-T1 264 GLVYDSQSDFPKAIECYEKSLKIAREAGD 292 33333344555566666655555444444 PP == domain 6 score: 0.7 bits; conditional E-value: 1.4 Rapsyn_N 38 dredkfrllGylitahsemGkykealefsl 67 +d f lG ++ + s++ k e e sl FUN_000362-T1 335 TEGDAFFNLGLVYDSQSDFPKAVECYEKSL 364 457889999999999999888776665544 PP == domain 7 score: 11.7 bits; conditional E-value: 0.00052 Rapsyn_N 16 lyesndtekalrvWrkvlkktsd...r...edkfrllGylitahsemGkykealefslaqlniaeeledP 79 + d ka+ + k lk + + r +d + lG+l+++ s++ k a+e + lnia+e dP FUN_000362-T1 347 YDSQSDFPKAVECYEKSLKIAKEagdRtleGDAYLNLGCLYNSESDFPK---AIECDEKSLNIAREAGDP 413 445678889999999988755441113333688999*********9766...899999********9998 PP == domain 8 score: 1.5 bits; conditional E-value: 0.75 Rapsyn_N 11 ekGlklyesndtekalrvWrkvlkktsdredk......frllGylitahsemGkykealefsla 68 + Gl + + + k++ + + lk + +d+ + lG+++++ se+ k e +e sl+ FUN_000362-T1 422 NLGLVYFSQSNFPKSIECYEETLKIVREAGDRvregkaYFNLGFVYNSQSEFPKSIECFEKSLK 485 567888888888888888887777554444430001115579********99999888887765 PP == domain 9 score: -1.2 bits; conditional E-value: 5.3 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqln 71 + +d + lG ++ + s++ k e e + l FUN_000362-T1 493 RATEGDAYLNLGRVYFSQSDFCKAIECYE---ESLK 525 34467888889999999999888555444...3344 PP == domain 10 score: 2.0 bits; conditional E-value: 0.52 Rapsyn_N 12 kGlklyesndtekalrvWrkvlkktsd.....redk.frllGylitahsemGkykealefsl 67 Gl +y + d a+ + k lk +s+ e+k + lG ++ + s++ k e e sl FUN_000362-T1 543 VGLFFYSQGDFPIAIECYEKSLKIASEgvdwaTEGKvYLNLGHVYYSQSDFRKETECCENSL 604 59999******************998633333344415569999999999888777766554 PP == domain 11 score: 2.0 bits; conditional E-value: 0.53 Rapsyn_N 15 klyesndtekalrvWrkvlk......ktsdredkfrllGylitahsemGkykeale 64 y + + ka++ + k+l + + +d + lG +++h ++ k e e FUN_000362-T1 753 VYYSRSEFRKAIKCYEKALNiftevgEQALEGDSYLKLGNAYKSHNDFPKAIECYE 808 56777777777777777776222111234467899999*******99988776655 PP == domain 12 score: 4.1 bits; conditional E-value: 0.12 Rapsyn_N 20 ndtekalrvWrkvl...k...ktsdredkfrllGylitahsemGkykealefslaqlniaeele 77 nd ka+ + k l + + + ++ f lG+++++ s++ k a+e+ + lnia+e FUN_000362-T1 798 NDFPKAIECYEKSLiiaRragDVVREGNAFFNLGIVYNSCSDLPK---AIEYYEKSLNIAREAG 858 66666776666666222211123567788999**********998...8999999999*99965 PP == domain 13 score: -2.1 bits; conditional E-value: 9.9 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaeel 76 + + lG+++++ ++ +a++ + lnia+e FUN_000362-T1 944 GKAYFTLGVVYESRCDLT---NAIDCYVKSLNIAREA 977 334556888888888764...6788888888888875 PP == domain 14 score: 1.6 bits; conditional E-value: 0.72 Rapsyn_N 50 itahsemGkykealefslaqlniaeeled 78 + + ++ a+e + lnia+e+ d FUN_000362-T1 1125 Y---LSLSDFRKAIECHEKGLNIAREVGD 1150 4...3456799***************876 PP == domain 15 score: 1.4 bits; conditional E-value: 0.85 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaee 75 + f lG ++++ ++ k a+ef + lnia+e FUN_000362-T1 1196 SGYF-NLGTVYKSRNDLPK---AIEFYEKSLNIARE 1227 3334.47999999999877...899999999**998 PP == domain 16 score: 1.9 bits; conditional E-value: 0.57 Rapsyn_N 21 dtekalrvWrkvlkktsdredk......frllGylitahsemGkykealefslaqlniaeele 77 d +a+ + k l +++ +d+ + lG ++++ ++ k a+ef + lni++e FUN_000362-T1 1250 DFRNAIECYEKSLLIATKAGDRaaegsgYFNLGTVYKSRNDLPK---AMEFYEKSLNISREAG 1309 55555555555543333222221111114458999999999987...7889999999999965 PP == domain 17 score: 4.6 bits; conditional E-value: 0.086 Rapsyn_N 13 GlklyesndtekalrvWrkvlkktsdred......kfrllGylitahsemGkykealefslaqlniaee 75 Gl + + ka+ + k l + + +d + lG++++ h ++ k e +e lnia+e FUN_000362-T1 1322 GLIYDSQSNFSKAIECYEKSLNIAWEAGDqategkAYFSLGIVYKLHKDFAKAFECFEK---SLNIARE 1387 665556778888888888888755444331111115778**********9998887765...4677777 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.016 9.5 9 70 .. 37 104 .. 29 108 .. 0.78 2 ? -1.1 0.0 5.8 3.4e+03 31 59 .. 185 213 .. 178 242 .. 0.60 3 ? 4.7 0.0 0.089 52 19 53 .. 252 287 .. 231 307 .. 0.69 4 ? 3.6 0.0 0.21 1.2e+02 25 69 .. 338 383 .. 310 388 .. 0.75 5 ? 1.3 0.0 1 6e+02 22 49 .. 415 443 .. 389 464 .. 0.69 6 ? 7.5 0.1 0.012 7 11 50 .. 479 525 .. 469 542 .. 0.74 7 ? 2.1 0.0 0.58 3.4e+02 25 53 .. 538 568 .. 530 587 .. 0.79 8 ? -1.0 0.0 5.4 3.1e+03 4 41 .. 552 595 .. 549 603 .. 0.59 9 ? 4.9 0.2 0.079 46 29 70 .. 750 791 .. 742 809 .. 0.68 10 ? -0.6 0.0 4.2 2.4e+03 2 57 .. 797 852 .. 796 860 .. 0.74 11 ? -0.2 0.2 3.1 1.8e+03 5 49 .. 840 890 .. 836 911 .. 0.68 12 ? 0.8 0.1 1.5 8.8e+02 18 49 .. 899 930 .. 876 942 .. 0.76 13 ? 4.6 0.0 0.099 58 20 60 .. 1112 1152 .. 1103 1166 .. 0.73 14 ? 0.9 0.0 1.4 8.2e+02 4 49 .. 1170 1221 .. 1167 1244 .. 0.67 15 ? 5.4 0.1 0.054 31 3 50 .. 1209 1262 .. 1207 1272 .. 0.71 16 ! 8.1 0.0 0.0081 4.7 2 70 .. 1248 1322 .. 1247 1327 .. 0.80 17 ? 5.6 0.2 0.047 27 2 49 .. 1328 1381 .. 1327 1388 .. 0.80 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.016 ANAPC3 9 iflaerlla.....aepespedayl.lAqclflngqykrAyellrkaklnekslgcryllAqcllkLk 70 i ++e+ l+ ++ ++ dayl l+ ++ +++++ +A+e +++ k g r+ ++++++ L+ FUN_000362-T1 37 IECYEKSLKiasegGDRATEGDAYLnLGRVYDSQSDFPKAIECYEESLKIAKEAGDRVRKGKAYFNLG 104 566666663322345667778899978********************777888899999999999986 PP == domain 2 score: -1.1 bits; conditional E-value: 5.8 ANAPC3 31 qclflngqykrAyellrkaklnekslgcr 59 ++ +++++ +A+++ +k+ k g r FUN_000362-T1 185 RVYDSESNFPKAIKFYKKSLKIAKKAGDR 213 56677777777777777773333333443 PP == domain 3 score: 4.7 bits; conditional E-value: 0.089 ANAPC3 19 epespedayl.lAqclflngqykrAyellrkaklne 53 ++ ++ dayl l++++ +++++ +A+e +k+ FUN_000362-T1 252 DRVTEGDAYLnLGLVYDSQSDFPKAIECYEKSLKIA 287 444566799978******************994434 PP == domain 4 score: 3.6 bits; conditional E-value: 0.21 ANAPC3 25 dayl.lAqclflngqykrAyellrkaklnekslgcryllAqcllkL 69 da+ l++++ +++++ +A+e +k+ k g r l + ++l L FUN_000362-T1 338 DAFFnLGLVYDSQSDFPKAVECYEKSLKIAKEAGDRTLEGDAYLNL 383 4444389****************99966677778887777777766 PP == domain 5 score: 1.3 bits; conditional E-value: 1 ANAPC3 22 spedayl.lAqclflngqykrAyellrka 49 ++ ayl l++++f+++++ + +e ++ FUN_000362-T1 415 REGKAYLnLGLVYFSQSNFPKSIECYEET 443 445588868*********99988888877 PP == domain 6 score: 7.5 bits; conditional E-value: 0.012 ANAPC3 11 laerlla.....aepespedayl.lAqclflngqykrAyellrka.k 50 ++e+ l+ ++ ++ dayl l+ ++f+++++ +A+e +++ k FUN_000362-T1 479 CFEKSLKtasegRDRATEGDAYLnLGRVYFSQSDFCKAIECYEESlK 525 5666663222335566777899978****************999844 PP == domain 7 score: 2.1 bits; conditional E-value: 0.58 ANAPC3 25 dayll.AqclflngqykrAyellrka.klne 53 dayl ++ ++++g++ A+e +k+ k+++ FUN_000362-T1 538 DAYLNvGLFFYSQGDFPIAIECYEKSlKIAS 568 78885599***************99955544 PP == domain 8 score: -1.0 bits; conditional E-value: 5.4 ANAPC3 4 qyknAiflaerlla.....aepespedayl.lAqclflngqykr 41 ++ Ai ++e+ l+ + ++ +yl l+ ++++++++++ FUN_000362-T1 552 DFPIAIECYEKSLKiasegVDWATEGKVYLnLGHVYYSQSDFRK 595 55667777777773222223333344466656888888888765 PP == domain 9 score: 4.9 bits; conditional E-value: 0.079 ANAPC3 29 lAqclflngqykrAyellrkaklnekslgcryllAqcllkLk 70 l+ ++++++++++A++ +ka + + +g l + ++lkL+ FUN_000362-T1 750 LGVVYYSRSEFRKAIKCYEKALNIFTEVGEQALEGDSYLKLG 791 677888888888888888888444444555555555555554 PP == domain 10 score: -0.6 bits; conditional E-value: 4.2 ANAPC3 2 nhqyknAiflaerllaaepespedayllAqclflngq.ykrAyellrkaklnekslg 57 ++++ Ai ++e+ l ++++ d+ ++++f++g y+++ +l + + +eksl+ FUN_000362-T1 797 HNDFPKAIECYEKSL-IIARRAGDVVREGNAFFNLGIvYNSCSDLPKAIEYYEKSLN 852 678889999999999.99999999888888888888745555554444477777665 PP == domain 11 score: -0.2 bits; conditional E-value: 3.1 ANAPC3 5 yknAiflaerll.....aaepespedayl.lAqclflngqykrAyellrka 49 + Ai ++e+ l a ++ + +ayl l++++ + + +A++ +k+ FUN_000362-T1 840 LPKAIEYYEKSLniareAGDKAKEGNAYLnLGNAYMSHDESPKAFNCYEKS 890 567999999999554443444445556654688888777777777777776 PP == domain 12 score: 0.8 bits; conditional E-value: 1.5 ANAPC3 18 aepespedayllAqclflngqykrAyellrka 49 + +++ ++ y l+ +++ +g+ +A+e +k+ FUN_000362-T1 899 DRATEGKANYNLGSVYLCRGDRSKAIECYEKS 930 445555678889***************99988 PP == domain 13 score: 4.6 bits; conditional E-value: 0.099 ANAPC3 20 pespedayllAqclflngqykrAyellrkaklnekslgcry 60 ++ +e+ + l+ ++++++++++A+e +k + + +g r FUN_000362-T1 1112 ATKAEAYFHLGAVYLSLSDFRKAIECHEKGLNIAREVGDRT 1152 5678889999**************99877644444445555 PP == domain 14 score: 0.9 bits; conditional E-value: 1.4 ANAPC3 4 qyknAiflaerllaaepesped.......ayllAqclflngqykrAyellrka 49 ++ Ai ++e+ l + ++++ d + l++++ ++++ +A+e+ +k+ FUN_000362-T1 1170 DFPKAIECYEKSL-DIAREAGDrategsgYFNLGTVYKSRNDLPKAIEFYEKS 1221 5678999999999.444444441222223455677777777777777777776 PP == domain 15 score: 5.4 bits; conditional E-value: 0.054 ANAPC3 3 hqyknAiflaerllaaepesped......ayl.lAqclflngqykrAyellrkak 50 +++ Ai ++e+ l ++++ d ayl l++++ ++++++ A+e +k+ FUN_000362-T1 1209 NDLPKAIEFYEKSL-NIAREEGDwaregkAYLnLGLVYDSQSDFRNAIECYEKSL 1262 56677888888888.3333333333444488868****************99984 PP == domain 16 score: 8.1 bits; conditional E-value: 0.0081 ANAPC3 2 nhqyknAiflaerll..aaepesped....ayllAqclflngqykrAyellrkaklnekslgcryllAqcllkLk 70 + +++nAi ++e+ l a+++ + + + l++++ ++++ +A+e+ +k+ + ++ g r ++++l L+ FUN_000362-T1 1248 QSDFRNAIECYEKSLliATKAGDRAAegsgYFNLGTVYKSRNDLPKAMEFYEKSLNISREAGDRATEGKACLNLG 1322 67899*********96634444444455557779********************777777899999999999987 PP == domain 17 score: 5.6 bits; conditional E-value: 0.047 ANAPC3 2 nhqyknAiflaerll.....a.aepespedayllAqclflngqykrAyellrka 49 + +++ Ai ++e+ l a +++++ ++ + l+ ++ l +++++A+e ++k+ FUN_000362-T1 1328 QSNFSKAIECYEKSLniaweAgDQATEGKAYFSLGIVYKLHKDFAKAFECFEKS 1381 678999*********666652477777778888999999999999999999998 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.061 35 14 32 .. 67 85 .. 59 91 .. 0.89 2 ? 2.6 0.0 0.35 2e+02 3 32 .. 96 125 .. 94 130 .. 0.89 3 ? 5.7 0.0 0.039 23 14 32 .. 187 205 .. 177 216 .. 0.89 4 ? -1.1 0.0 5.2 3e+03 14 31 .. 227 244 .. 220 250 .. 0.88 5 ? 5.1 0.1 0.058 34 11 32 .. 264 285 .. 257 292 .. 0.87 6 ? 4.1 0.0 0.12 70 12 32 .. 345 365 .. 339 374 .. 0.86 7 ? 0.9 0.0 1.2 7e+02 19 32 .. 512 525 .. 509 533 .. 0.86 8 ? 0.1 0.0 2.2 1.3e+03 17 32 .. 550 565 .. 549 577 .. 0.84 9 ? 6.7 0.0 0.019 11 17 37 .. 757 777 .. 746 788 .. 0.84 10 ? -0.0 0.0 2.4 1.4e+03 17 31 .. 797 811 .. 793 812 .. 0.86 11 ? 0.3 0.1 1.8 1.1e+03 19 33 .. 839 853 .. 827 872 .. 0.84 12 ? 0.1 0.0 2.2 1.3e+03 18 32 .. 918 932 .. 916 933 .. 0.85 13 ? 0.0 0.0 2.3 1.3e+03 5 32 .. 945 972 .. 941 981 .. 0.86 14 ? 1.3 0.0 0.93 5.4e+02 19 33 .. 1170 1184 .. 1168 1194 .. 0.86 15 ? 0.1 0.0 2.1 1.2e+03 16 32 .. 1207 1223 .. 1194 1224 .. 0.83 16 ? 4.9 0.1 0.07 40 5 31 .. 1236 1262 .. 1233 1270 .. 0.86 17 ? -1.4 0.0 6.3 3.6e+03 16 32 .. 1287 1303 .. 1277 1304 .. 0.83 18 ? 7.6 0.0 0.01 5.8 8 32 .. 1319 1343 .. 1313 1348 .. 0.85 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.061 MIT 14 eDnagnyeeAlelYkeale 32 +D++ ++ +A+e+Y+e+l+ FUN_000362-T1 67 YDSQSDFPKAIECYEESLK 85 799*************997 PP == domain 2 score: 2.6 bits; conditional E-value: 0.35 MIT 3 kAlelvkkAveeDnagnyeeAlelYkeale 32 k++++++ D++ ++++ +e+Y+++l+ FUN_000362-T1 96 KGKAYFNLGLVFDSQSDFSKSIECYEKSLK 125 778888899999***************986 PP == domain 3 score: 5.7 bits; conditional E-value: 0.039 MIT 14 eDnagnyeeAlelYkeale 32 +D++ n+ +A+++Yk++l+ FUN_000362-T1 187 YDSESNFPKAIKFYKKSLK 205 79**************997 PP == domain 4 score: -1.1 bits; conditional E-value: 5.2 MIT 14 eDnagnyeeAlelYkeal 31 +D+ n+ + +e+Y+++l FUN_000362-T1 227 YDTLSNFPKSIECYEKSL 244 688999*********998 PP == domain 5 score: 5.1 bits; conditional E-value: 0.058 MIT 11 AveeDnagnyeeAlelYkeale 32 +D++ ++ +A+e+Y+++l+ FUN_000362-T1 264 GLVYDSQSDFPKAIECYEKSLK 285 5679***************996 PP == domain 6 score: 4.1 bits; conditional E-value: 0.12 MIT 12 veeDnagnyeeAlelYkeale 32 +D++ ++ +A+e+Y+++l+ FUN_000362-T1 345 LVYDSQSDFPKAVECYEKSLK 365 669***************997 PP == domain 7 score: 0.9 bits; conditional E-value: 1.2 MIT 19 nyeeAlelYkeale 32 ++ +A+e+Y+e+l+ FUN_000362-T1 512 DFCKAIECYEESLK 525 7889*******997 PP == domain 8 score: 0.1 bits; conditional E-value: 2.2 MIT 17 agnyeeAlelYkeale 32 +g++ A+e+Y+++l+ FUN_000362-T1 550 QGDFPIAIECYEKSLK 565 688999*******997 PP == domain 9 score: 6.7 bits; conditional E-value: 0.019 MIT 17 agnyeeAlelYkealelLlqa 37 + ++ +A+++Y++al+ ++ + FUN_000362-T1 757 RSEFRKAIKCYEKALNIFTEV 777 67899*************876 PP == domain 10 score: -0.0 bits; conditional E-value: 2.4 MIT 17 agnyeeAlelYkeal 31 +++ +A+e+Y+++l FUN_000362-T1 797 HNDFPKAIECYEKSL 811 67899*******986 PP == domain 11 score: 0.3 bits; conditional E-value: 1.8 MIT 19 nyeeAlelYkealel 33 + +A+e+Y+++l+ FUN_000362-T1 839 DLPKAIEYYEKSLNI 853 5679******99975 PP == domain 12 score: 0.1 bits; conditional E-value: 2.2 MIT 18 gnyeeAlelYkeale 32 g+ ++A+e+Y+++l+ FUN_000362-T1 918 GDRSKAIECYEKSLH 932 67899******9986 PP == domain 13 score: 0.0 bits; conditional E-value: 2.3 MIT 5 lelvkkAveeDnagnyeeAlelYkeale 32 +++++ v ++++ + A+++Y ++l+ FUN_000362-T1 945 KAYFTLGVVYESRCDLTNAIDCYVKSLN 972 66778889999999*********99987 PP == domain 14 score: 1.3 bits; conditional E-value: 0.93 MIT 19 nyeeAlelYkealel 33 ++ +A+e+Y+++l+ FUN_000362-T1 1170 DFPKAIECYEKSLDI 1184 6789********985 PP == domain 15 score: 0.1 bits; conditional E-value: 2.1 MIT 16 nagnyeeAlelYkeale 32 ++++ +A+e+Y+++l+ FUN_000362-T1 1207 SRNDLPKAIEFYEKSLN 1223 678899********997 PP == domain 16 score: 4.9 bits; conditional E-value: 0.07 MIT 5 lelvkkAveeDnagnyeeAlelYkeal 31 +++++ +D++ ++ A+e+Y+++l FUN_000362-T1 1236 KAYLNLGLVYDSQSDFRNAIECYEKSL 1262 5667778889**************997 PP == domain 17 score: -1.4 bits; conditional E-value: 6.3 MIT 16 nagnyeeAlelYkeale 32 ++++ +A+e+Y+++l+ FUN_000362-T1 1287 SRNDLPKAMEFYEKSLN 1303 5788999*******986 PP == domain 18 score: 7.6 bits; conditional E-value: 0.01 MIT 8 vkkAveeDnagnyeeAlelYkeale 32 ++ +D++ n+++A+e+Y+++l+ FUN_000362-T1 1319 LNLGLIYDSQSNFSKAIECYEKSLN 1343 5666679***************997 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 6.1 3.5e+03 149 174 .. 31 56 .. 24 59 .. 0.80 2 ? 2.6 0.0 0.26 1.5e+02 135 173 .. 58 95 .. 36 99 .. 0.90 3 ? -1.3 0.0 4 2.3e+03 134 167 .. 77 129 .. 76 138 .. 0.61 4 ? 2.3 0.0 0.32 1.9e+02 135 173 .. 138 175 .. 134 179 .. 0.92 5 ? 0.8 0.0 0.89 5.2e+02 137 174 .. 180 216 .. 178 219 .. 0.84 6 ? 5.2 0.0 0.04 23 134 174 .. 217 256 .. 215 259 .. 0.89 7 ? 4.8 0.0 0.055 32 135 174 .. 258 296 .. 257 299 .. 0.90 8 ? -0.9 0.0 3.1 1.8e+03 136 174 .. 299 336 .. 297 339 .. 0.79 9 ? 1.9 0.0 0.4 2.3e+02 148 174 .. 350 376 .. 315 379 .. 0.72 10 ? -0.6 0.0 2.5 1.4e+03 135 169 .. 378 411 .. 356 419 .. 0.49 11 ? 0.7 0.0 0.95 5.5e+02 135 174 .. 498 536 .. 497 539 .. 0.88 12 ? -1.2 0.0 3.6 2.1e+03 132 172 .. 555 614 .. 554 618 .. 0.81 13 ? -0.4 0.0 2.1 1.2e+03 149 172 .. 758 781 .. 747 785 .. 0.85 14 ? 3.8 0.0 0.11 64 135 170 .. 785 819 .. 781 826 .. 0.91 15 ? 0.8 0.0 0.9 5.2e+02 153 175 .. 842 864 .. 835 866 .. 0.88 16 ? 6.6 0.0 0.015 8.7 136 174 .. 866 903 .. 864 906 .. 0.92 17 ? -1.6 0.0 5.1 2.9e+03 149 171 .. 958 980 .. 921 984 .. 0.53 18 ? 0.8 0.0 0.94 5.4e+02 136 174 .. 1117 1154 .. 1108 1157 .. 0.79 19 ? 1.9 0.0 0.43 2.5e+02 149 174 .. 1169 1194 .. 1142 1196 .. 0.77 20 ? 1.9 0.0 0.41 2.4e+02 135 174 .. 1236 1274 .. 1214 1277 .. 0.89 21 ? -0.5 0.1 2.2 1.3e+03 137 174 .. 1278 1314 .. 1254 1317 .. 0.69 22 ? -0.7 0.0 2.6 1.5e+03 149 174 .. 1329 1354 .. 1321 1357 .. 0.84 23 ? 1.4 0.0 0.6 3.5e+02 147 172 .. 1356 1392 .. 1332 1396 .. 0.65 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 6.1 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkee 174 +++ ++++e++l++a + g+r++e FUN_000362-T1 31 SDFSKSIECYEKSLKIASEGGDRATE 56 5678899**********999999877 PP == domain 2 score: 2.6 bits; conditional E-value: 0.26 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrke 173 daYl+ + +++ + +a++++e +l++a+++g+r + FUN_000362-T1 58 DAYLNLGRVYDSQ-SDFPKAIECYEESLKIAKEAGDRVR 95 7999999999998.999****************999865 PP == domain 3 score: -1.3 bits; conditional E-value: 4 DUF7380 134 idaYlesaeeledg...................seewvdalkrleRAlqlaaq 167 i++Y es + +++ +++ ++++e++l++a + FUN_000362-T1 77 IECYEESLKIAKEAgdrvrkgkayfnlglvfdsQSDFSKSIECYEKSLKIASE 129 55554444444444444555555555555555447788899999999999876 PP == domain 4 score: 2.3 bits; conditional E-value: 0.32 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrke 173 daYl+ + e++ + + ++ +e++l++a+++g+r+ FUN_000362-T1 138 DAYLNLRRVYESQ-SDFAKPIQFYEKSLKIAREAGDRAL 175 79***99999999.9999*****************9975 PP == domain 5 score: 0.8 bits; conditional E-value: 0.89 DUF7380 137 YlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 Yl++ + +++ ++ +a+k ++++l++a+++g+r +e FUN_000362-T1 180 YLKVGRVYDSE-SNFPKAIKFYKKSLKIAKKAGDRVRE 216 77777777777.8899*****************99765 PP == domain 6 score: 5.2 bits; conditional E-value: 0.04 DUF7380 134 idaYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 i+aYl+ + ++ ++ + ++++e++l++a+++g+r +e FUN_000362-T1 217 IKAYLSLGRVYDTL-SNFPKSIECYEKSLTIAKEAGDRVTE 256 899**999888887.99*******************99776 PP == domain 7 score: 4.8 bits; conditional E-value: 0.055 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daYl+ +++ + +a++++e++l++a+++g+r +e FUN_000362-T1 258 DAYLNLGLVYDSQ-SDFPKAIECYEKSLKIAREAGDRVRE 296 7999999999999.999******************99776 PP == domain 8 score: -0.9 bits; conditional E-value: 3.1 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aYl+ ++ + + ++++e++l++a + g+r++e FUN_000362-T1 299 AYLNLGLVYGSQ-GIFGKSIECYEKSLRIASEGGDRATE 336 667666666666.6777899***********99999887 PP == domain 9 score: 1.9 bits; conditional E-value: 0.4 DUF7380 148 seewvdalkrleRAlqlaaqlgkrkee 174 + +a++++e++l++a+++g+r e FUN_000362-T1 350 QSDFPKAVECYEKSLKIAKEAGDRTLE 376 46688999************9998765 PP == domain 10 score: -0.6 bits; conditional E-value: 2.5 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlg 169 daYl+ ++ + +a+++ e++l +a+++g FUN_000362-T1 378 DAYLNLGCLYNSE-SDFPKAIECDEKSLNIAREAG 411 2333333333333.555666666666666666665 PP == domain 11 score: 0.7 bits; conditional E-value: 0.95 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 daYl+ + ++ + +a++++e +l++a+++g r+ e FUN_000362-T1 498 DAYLNLGRVYFSQ-SDFCKAIECYEESLKIAREAGNRDLE 536 6899999888898.9999****************999765 PP == domain 12 score: -1.2 bits; conditional E-value: 3.6 DUF7380 132 lAidaYlesaeeledg...................seewvdalkrleRAlqlaaqlgkrk 172 +Ai++Y +s + + +g + + ++ e +l++a+++g+++ FUN_000362-T1 555 IAIECYEKSLKIASEGvdwategkvylnlghvyysQSDFRKETECCENSLSIAKEAGDQA 614 789999888888888888888888888888888866777788999999999999999876 PP == domain 13 score: -0.4 bits; conditional E-value: 2.1 DUF7380 149 eewvdalkrleRAlqlaaqlgkrk 172 e+ +a+k++e+Al + ++g+++ FUN_000362-T1 758 SEFRKAIKCYEKALNIFTEVGEQA 781 567899**********99999886 PP == domain 14 score: 3.8 bits; conditional E-value: 0.11 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgk 170 d+Yl+ + ++ + + +a++++e++l +a+++g+ FUN_000362-T1 785 DSYLKLGNAYKSH-NDFPKAIECYEKSLIIARRAGD 819 79**********9.******************9987 PP == domain 15 score: 0.8 bits; conditional E-value: 0.9 DUF7380 153 dalkrleRAlqlaaqlgkrkeep 175 +a++++e++l +a+++g++++e FUN_000362-T1 842 KAIEYYEKSLNIAREAGDKAKEG 864 789****************9985 PP == domain 16 score: 6.6 bits; conditional E-value: 0.015 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aYl+ + + +e+ +a++++e++l +a+++g+r++e FUN_000362-T1 866 AYLNLGNAYMSH-DESPKAFNCYEKSLNIAREAGDRATE 903 99**99999999.**********************9987 PP == domain 17 score: -1.6 bits; conditional E-value: 5.1 DUF7380 149 eewvdalkrleRAlqlaaqlgkr 171 ++a++++ ++l +a+++g+r FUN_000362-T1 958 CDLTNAIDCYVKSLNIAREAGDR 980 34456667777777777776665 PP == domain 18 score: 0.8 bits; conditional E-value: 0.94 DUF7380 136 aYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 aY ++ + +a+++ e+ l +a+++g+r +e FUN_000362-T1 1117 AYFHLGAVYLSL-SDFRKAIECHEKGLNIAREVGDRTTE 1154 555555555555.678899****************9887 PP == domain 19 score: 1.9 bits; conditional E-value: 0.43 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkee 174 + +a++++e++l +a+++g+r++e FUN_000362-T1 1169 SDFPKAIECYEKSLDIAREAGDRATE 1194 567899****************9876 PP == domain 20 score: 1.9 bits; conditional E-value: 0.41 DUF7380 135 daYlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 +aYl+ +++ + +a++++e++l +a ++g+r+ e FUN_000362-T1 1236 KAYLNLGLVYDSQ-SDFRNAIECYEKSLLIATKAGDRAAE 1274 5888888888888.9999*****************99876 PP == domain 21 score: -0.5 bits; conditional E-value: 2.2 DUF7380 137 YlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 Y + + +++ + +a + +e++l +++++g+r++e FUN_000362-T1 1278 YFNLGTVYKSR-NDLPKAMEFYEKSLNISREAGDRATE 1314 44444444555.78889999999999999999999876 PP == domain 22 score: -0.7 bits; conditional E-value: 2.6 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkee 174 ++++a++++e++l +a ++g++++e FUN_000362-T1 1329 SNFSKAIECYEKSLNIAWEAGDQATE 1354 568899*************9999877 PP == domain 23 score: 1.4 bits; conditional E-value: 0.6 DUF7380 147 g...........seewvdalkrleRAlqlaaqlgkrk 172 + + + +a++++e++l +a+++g+++ FUN_000362-T1 1356 KayfslgivyklHKDFAKAFECFEKSLNIAREAGDHA 1392 0444444444444778999999999999999999876 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 4 2.4e+03 18 31 .. 30 43 .. 27 45 .. 0.86 2 ? 1.0 0.0 1.8 1e+03 3 30 .. 59 82 .. 57 85 .. 0.68 3 ? 1.8 0.0 1 6e+02 3 31 .. 99 123 .. 97 125 .. 0.75 4 ? 1.5 0.0 1.3 7.5e+02 18 31 .. 190 203 .. 174 205 .. 0.82 5 ? 3.7 0.0 0.26 1.5e+02 3 31 .. 259 283 .. 257 285 .. 0.70 6 ? 1.9 0.0 0.97 5.6e+02 18 31 .. 350 363 .. 339 365 .. 0.78 7 ? 0.4 0.0 2.8 1.6e+03 3 31 .. 539 563 .. 537 565 .. 0.70 8 ? 3.2 0.1 0.37 2.1e+02 21 31 .. 760 770 .. 746 772 .. 0.76 9 ? 0.9 0.0 2 1.2e+03 20 31 .. 799 810 .. 789 811 .. 0.89 10 ? 3.0 0.0 0.42 2.4e+02 20 31 .. 839 850 .. 838 852 .. 0.88 11 ? 7.0 0.0 0.024 14 2 31 .. 905 930 .. 904 931 .. 0.86 12 ? 0.3 0.0 3.1 1.8e+03 2 30 .. 1116 1140 .. 1115 1143 .. 0.63 13 ? 2.3 0.0 0.71 4.1e+02 20 31 .. 1170 1181 .. 1156 1183 .. 0.78 14 ? 2.5 0.0 0.59 3.4e+02 18 31 .. 1208 1221 .. 1196 1223 .. 0.73 15 ? 0.9 0.0 1.9 1.1e+03 3 31 .. 1237 1261 .. 1235 1262 .. 0.67 16 ? 1.7 0.0 1.1 6.4e+02 18 31 .. 1288 1301 .. 1276 1303 .. 0.73 17 ? 5.2 0.0 0.086 50 3 31 .. 1317 1341 .. 1315 1343 .. 0.73 18 ? 2.9 0.0 0.45 2.6e+02 19 31 .. 1369 1381 .. 1357 1383 .. 0.85 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 4 Sel1 18 pkDpekAlewyekA 31 + D +k++e+yek+ FUN_000362-T1 30 KSDFSKSIECYEKS 43 4599********96 PP == domain 2 score: 1.0 bits; conditional E-value: 1.8 Sel1 3 AqyrLGylylyGlgvpkDpekAlewyek 30 A+ +LG y D kA+e+ye FUN_000362-T1 59 AYLNLGR--VYD--SQSDFPKAIECYEE 82 6666663..222..256999******96 PP == domain 3 score: 1.8 bits; conditional E-value: 1 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+++LG ++ D +k++e+yek+ FUN_000362-T1 99 AYFNLGlV--FDS---QSDFSKSIECYEKS 123 77777755..444...67**********96 PP == domain 4 score: 1.5 bits; conditional E-value: 1.3 Sel1 18 pkDpekAlewyekA 31 + + kA+++y+k+ FUN_000362-T1 190 ESNFPKAIKFYKKS 203 67999*******96 PP == domain 5 score: 3.7 bits; conditional E-value: 0.26 Sel1 3 AqyrLGylylyGlgvpkDpekAlewyekA 31 A+ +LG y D kA+e+yek+ FUN_000362-T1 259 AYLNLGL--VYD--SQSDFPKAIECYEKS 283 5666663..223..2569*********96 PP == domain 6 score: 1.9 bits; conditional E-value: 0.97 Sel1 18 pkDpekAlewyekA 31 D kA+e+yek+ FUN_000362-T1 350 QSDFPKAVECYEKS 363 4599********96 PP == domain 7 score: 0.4 bits; conditional E-value: 2.8 Sel1 3 AqyrLG.ylylyGlgvpkDpekAlewyekA 31 A+ ++G +y +G D A+e+yek+ FUN_000362-T1 539 AYLNVGlFFYSQG-----DFPIAIECYEKS 563 6666666555555.....888999999986 PP == domain 8 score: 3.2 bits; conditional E-value: 0.37 Sel1 21 pekAlewyekA 31 +kA+++yekA FUN_000362-T1 760 FRKAIKCYEKA 770 68********9 PP == domain 9 score: 0.9 bits; conditional E-value: 2 Sel1 20 DpekAlewyekA 31 D kA+e+yek+ FUN_000362-T1 799 DFPKAIECYEKS 810 889*******96 PP == domain 10 score: 3.0 bits; conditional E-value: 0.42 Sel1 20 DpekAlewyekA 31 D kA+e+yek+ FUN_000362-T1 839 DLPKAIEYYEKS 850 788*******96 PP == domain 11 score: 7.0 bits; conditional E-value: 0.024 Sel1 2 eAqyrLG.ylylyGlgvpkDpekAlewyekA 31 +A y+LG ++ +G D +kA+e+yek+ FUN_000362-T1 905 KANYNLGsVYLCRG-----DRSKAIECYEKS 930 68999998777888.....9*********96 PP == domain 12 score: 0.3 bits; conditional E-value: 3.1 Sel1 2 eAqyrLGylylyGlgvpkDpekAlewyek 30 eA++ LG yl D +kA+e+ ek FUN_000362-T1 1116 EAYFHLGAVYLS----LSDFRKAIECHEK 1140 666666632232....4588899988887 PP == domain 13 score: 2.3 bits; conditional E-value: 0.71 Sel1 20 DpekAlewyekA 31 D kA+e+yek+ FUN_000362-T1 1170 DFPKAIECYEKS 1181 999*******97 PP == domain 14 score: 2.5 bits; conditional E-value: 0.59 Sel1 18 pkDpekAlewyekA 31 + D kA+e+yek+ FUN_000362-T1 1208 RNDLPKAIEFYEKS 1221 3499********96 PP == domain 15 score: 0.9 bits; conditional E-value: 1.9 Sel1 3 AqyrLGylylyGlgvpkDpekAlewyekA 31 A+ +LG y D + A+e+yek+ FUN_000362-T1 1237 AYLNLGL--VYD--SQSDFRNAIECYEKS 1261 5555553..222..2569999******96 PP == domain 16 score: 1.7 bits; conditional E-value: 1.1 Sel1 18 pkDpekAlewyekA 31 + D kA+e+yek+ FUN_000362-T1 1288 RNDLPKAMEFYEKS 1301 34999*******96 PP == domain 17 score: 5.2 bits; conditional E-value: 0.086 Sel1 3 AqyrLGylylyGlgvpkDpekAlewyekA 31 A+ +LG y + +kA+e+yek+ FUN_000362-T1 1317 ACLNLGL--IYD--SQSNFSKAIECYEKS 1341 7777775..233..256**********96 PP == domain 18 score: 2.9 bits; conditional E-value: 0.45 Sel1 19 kDpekAlewyekA 31 kD kA+e++ek+ FUN_000362-T1 1369 KDFAKAFECFEKS 1381 69*********96 PP >> Cohesin_load Cohesin loading factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.4 8.2e+02 369 423 .. 69 120 .. 25 168 .. 0.63 2 ? 3.0 0.0 0.061 36 316 427 .. 195 324 .. 174 412 .. 0.57 3 ! 6.3 0.0 0.0065 3.7 300 428 .. 420 565 .. 419 645 .. 0.78 4 ? 2.5 0.0 0.09 52 347 427 .. 734 811 .. 711 822 .. 0.78 5 ! 6.6 0.0 0.005 2.9 313 430 .. 838 974 .. 826 997 .. 0.67 6 ? 1.3 0.0 0.2 1.2e+02 356 427 .. 1114 1182 .. 1102 1196 .. 0.65 7 ! 10.7 0.0 0.0003 0.17 337 526 .. 1217 1391 .. 1162 1406 .. 0.74 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.4 Cohesin_load 369 vrsdwtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiy 423 ++sd+ ka e+ ee k +k+ ++++ k +++ gl++ ++ d ++ ++y FUN_000362-T1 69 SQSDFPKAIECYEESLKIAKEAGDRV---RKGKAYFNLGLVFDSQSDFSKSIECY 120 34444444444444444444444222...44444444444555555555544444 PP == domain 2 score: 3.0 bits; conditional E-value: 0.061 Cohesin_load 316 kaekfleealklleklkkslk..epslslseasak.aewlkvlrcylliylaf..................lalvrsdwtkasesleelkkllkks 390 ka+kf ++ lk+ +k ++ + + lsl ++++ +++ k+++cy + +++ ++ ++sd+ ka e+ e+ k +++ FUN_000362-T1 195 KAIKFYKKSLKIAKKAGDRVReiKAYLSLGRVYDTlSNFPKSIECYEKSLTIAkeagdrvtegdaylnlglVYDSQSDFPKAIECYEKSLKIAREA 290 777777777777777777666665556665555441344466666655555555555555555555555445556666666655554444444444 PP Cohesin_load 391 elslskslktllhyleglyaqgtgdleaAlaiyqspl 427 + + +++ gl++ ++g ++ ++y+++l FUN_000362-T1 291 G---DRVREGKAYLNLGLVYGSQGIFGKSIECYEKSL 324 4...333555555566666666666666666665544 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0065 Cohesin_load 300 YlLsgvaylpknsddkkaekfleealklleklkkslk.......................epslslseasakaewlkvlrcylliylaflalvrsd 372 Yl g++y + ++ k++++ ee+lk++++ ++ + + sl++as+ ++ ++ +yl+ l+ +++++sd FUN_000362-T1 420 YLNLGLVYFSQSNFP-KSIECYEETLKIVREAGDRVRegkayfnlgfvynsqsefpksieCFEKSLKTASEGRDRATEGDAYLN--LGRVYFSQSD 512 555678888888887.99999999999999999999888776666666666665555555334555666666666666666655..444899**** PP Cohesin_load 373 wtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspll 428 + ka e+ ee k +++ + + +l +++ gl++ ++gd A ++y+++l FUN_000362-T1 513 FCKAIECYEESLKIAREAG---NRDLEGDAYLNVGLFFYSQGDFPIAIECYEKSLK 565 ****999944444444444...456677788888*****************88775 PP == domain 4 score: 2.5 bits; conditional E-value: 0.09 Cohesin_load 347 akaewlkvlrcylliylaflalvrsdwtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspl 427 +++e + ++ +++ l+ ++ +rs+++ka ++ e++ + +++ ++++ l +++ g + + +d +A ++y+++l FUN_000362-T1 734 DRKEGDRATEGRFYFNLGVVYYSRSEFRKAIKCYEKALNIFTEVGEQA---LEGDSYLKLGNAYKSHNDFPKAIECYEKSL 811 666666777788899999999999999999999977777777777555...788888888999999999999999997765 PP == domain 5 score: 6.6 bits; conditional E-value: 0.005 Cohesin_load 313 ddk.kaekfleealklleklkkslk................epslslseas.............akaewlkvlrcylliylaflalvrsdwtkase 378 +d ka+++ e+ l++ ++ ++ k e s a+ + ++ ++ l+ ++l r+d +ka e FUN_000362-T1 838 SDLpKAIEYYEKSLNIAREAGDKAKegnaylnlgnaymshdE--------SpkafncyekslniAREAGDRATEGKANYNLGSVYLCRGDRSKAIE 925 333488888888888888888777766544444433333331........022222333333445555556666666777777***********77 PP Cohesin_load 379 sleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspllsl 430 + +k+l+ +++ ++++ +++ g+++ ++ dl+ A +y+++l+ FUN_000362-T1 926 CY---EKSLHIAGEAGDGTTEGKAYFTLGVVYESRCDLTNAIDCYVKSLNIA 974 75...55555556666999**************************9888665 PP == domain 6 score: 1.3 bits; conditional E-value: 0.2 Cohesin_load 356 rcylliylaflalvrsdwtkasesleelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqspl 427 ++ +++l+ ++l+ sd++ka e+ e+ + +++ + + ++ + + g++++ + d +A ++y+++l FUN_000362-T1 1114 KAEAYFHLGAVYLSLSDFRKAIECHEKGLNIAREVG---DRTTEGKASFHLGTVYHFQSDFPKAIECYEKSL 1182 555666777777777777777777755555555555...333566666666777777777777777776554 PP == domain 7 score: 10.7 bits; conditional E-value: 0.0003 Cohesin_load 337 epslslseasakaewlkvlrcylliylaflalvrsdwtkasesl.eelkkllkkselslskslktllhyleglyaqgtgdleaAlaiyqsplls 429 + sl+ a++ +w ++ ++yl+ l++++ ++sd+++a e+ ++l + k ++++ ++ g+++ +++dl +A++ y+++l+ FUN_000362-T1 1217 FYEKSLNIAREEGDWAREGKAYLN--LGLVYDSQSDFRNAIECYeKSLLIATKAGDRAA----EGSGYFNLGTVYKSRNDLPKAMEFYEKSLNI 1304 556788888999999999999999..788888999999999999666666655555554....5555677899999999999999999888866 PP Cohesin_load 430 llsseskttakdipselailaalnlllilrdpshpdtselnellekleplclshpnkslraayslvkalqantqnslleakkslqealqaakki 523 +++ + + a+lnl li+++ ++ s++ e ek ++ + ++++ + ++ ++++ ++ +++a ++ ++l++a+++ FUN_000362-T1 1305 S-----REAGD---RATEGKACLNLGLIYDSQ--SNFSKAIECYEKSLNIAWEAGDQATEGKAYFSLGIVYKLHKDFAKAFECFEKSLNIAREA 1388 5.....34444...788888999999998866..556777777777777777778888888888888888888888888888888888888887 PP Cohesin_load 524 knt 526 +++ FUN_000362-T1 1389 GDH 1391 766 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.43 2.5e+02 147 171 .. 183 207 .. 52 214 .. 0.62 2 ? 2.3 0.0 0.22 1.3e+02 149 213 .. 185 247 .. 172 256 .. 0.69 3 ? 2.5 0.0 0.2 1.2e+02 99 172 .. 217 288 .. 191 292 .. 0.69 4 ? 0.8 0.0 0.66 3.8e+02 138 215 .. 334 409 .. 292 423 .. 0.72 5 ? -1.8 0.0 4.1 2.4e+03 157 173 .. 513 529 .. 435 620 .. 0.60 6 ? 1.5 0.0 0.39 2.3e+02 145 212 .. 748 813 .. 737 827 .. 0.55 7 ! 8.5 0.0 0.0028 1.6 84 174 .. 1100 1188 .. 1092 1229 .. 0.78 8 ? 0.8 0.0 0.64 3.7e+02 145 215 .. 1199 1267 .. 1189 1279 .. 0.62 9 ? 3.8 0.0 0.08 46 136 211 .. 1270 1343 .. 1230 1344 .. 0.54 10 ! 8.0 0.0 0.004 2.3 98 191 .. 1307 1403 .. 1287 1407 .. 0.76 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.43 TPR_NPHP3 147 LagLyaqwgkfstaealykqaleiy 171 + ++y+ +f +a ++yk++l+i FUN_000362-T1 183 VGRVYDSESNFPKAIKFYKKSLKIA 207 3345555555555555555555555 PP == domain 2 score: 2.3 bits; conditional E-value: 0.22 TPR_NPHP3 149 gLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravair 213 ++y+ +f +a ++yk++l+i ++a d + +k + +l +y + + + +++++i FUN_000362-T1 185 RVYDSESNFPKAIKFYKKSLKIAKKA--GDRVREIKAYLSLGRVYDTLSNFPKSIECYEKSLTIA 247 67888888999999999999988776..3455555666666666666666666655555665555 PP == domain 3 score: 2.5 bits; conditional E-value: 0.2 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 + y +lGr +l+ ++++ +++L i a D + ++ +L +y+ f +a + y+++l+i + FUN_000362-T1 217 IKAYLSLGRVYDTLSNFPKSIECYEKSLTIAKEA--GDRVTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKIAR 288 3457777888888888888888888888887666..56777777888888888888888888888888888765 PP == domain 4 score: 0.8 bits; conditional E-value: 0.66 TPR_NPHP3 138 PlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravairkk 215 + + +L +y+ f +a + y+++l+i ++a d +l + l ly+ + + a + +++++i ++ FUN_000362-T1 334 ATEGDAFFNLGLVYDSQSDFPKAVECYEKSLKIAKEA--GDRTLEGDAYLNLGCLYNSESDFPKAIECDEKSLNIARE 409 5556677788888999999999999999999998876..356666667777888888888888888888887777665 PP == domain 5 score: -1.8 bits; conditional E-value: 4.1 TPR_NPHP3 157 fstaealykqaleiyen 173 f +a + y+++l+i ++ FUN_000362-T1 513 FCKAIECYEESLKIARE 529 33333333333333332 PP == domain 6 score: 1.5 bits; conditional E-value: 0.39 TPR_NPHP3 145 hqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravai 212 +L +y + +f++a + y++al+i+ + G++ l + l + y+ ++ + a + ++++ i FUN_000362-T1 748 FNLGVVYYSRSEFRKAIKCYEKALNIFTEV-GEQ-ALEGDSYLKLGNAYKSHNDFPKAIECYEKSLII 813 445566666677777777777777776543.322.222333334444444444444444444444444 PP == domain 7 score: 8.5 bits; conditional E-value: 0.0028 TPR_NPHP3 84 kledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 ++e++ + + a+ a+ y lG l+ +a++ ++ L+i + D +++ +L ++y f +a + y+++l+i ++a FUN_000362-T1 1100 QIETEEDYAGDRATKAEAYFHLGAVYLSLSDFRKAIECHEKGLNIAREV--GDRTTEGKASFHLGTVYHFQSDFPKAIECYEKSLDIAREA 1188 4555544455667779****************************96665..599999******************************9876 PP == domain 8 score: 0.8 bits; conditional E-value: 0.64 TPR_NPHP3 145 hqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravairkk 215 +L ++y ++ + +a ++y+++l+i +++ d k + l l+y q + a + ++++ i k FUN_000362-T1 1199 FNLGTVYKSRNDLPKAIEFYEKSLNIAREE--GDWAREGKAYLNLGLVYDSQSDFRNAIECYEKSLLIATK 1267 456666777777777777777777776654..244444555556666666666666666666666655555 PP == domain 9 score: 3.8 bits; conditional E-value: 0.08 TPR_NPHP3 136 DhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkrava 211 D ++ + +L ++y ++ + +a ++y+++l+i ++a d + k l l+y q ++ a + +++++ FUN_000362-T1 1270 DRAAEGSGYFNLGTVYKSRNDLPKAMEFYEKSLNISREA--GDRATEGKACLNLGLIYDSQSNFSKAIECYEKSLN 1343 555555556666667777777777777777777766655..24444455555566666666666555555555544 PP == domain 10 score: 8.0 bits; conditional E-value: 0.004 TPR_NPHP3 98 vadlyealGrflkdlgllsqalpaLqraLeiRetald.....PDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakel 186 a + G+ + +lgl+ + + +a+e e +l+ D+ ++++ L +y + f++a++ ++++l+i ++a dh v + FUN_000362-T1 1307 EAGDRATEGKACLNLGLIYDSQSNFSKAIECYEKSLNiaweaGDQATEGKAYFSLGIVYKLHKDFAKAFECFEKSLNIAREA--GDHAGVSRAN 1398 4555567788899999999999999999999999986444446899999999999999999999999999999999999886..4777777666 PP TPR_NPHP3 187 ealal 191 + la+ FUN_000362-T1 1399 QYLAN 1403 66665 PP >> SHPRH_helical-1st E3 ubiquitin-protein ligase SHPRH, first helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 7 4.1e+03 37 60 .. 30 53 .. 26 68 .. 0.85 2 ? 3.0 0.0 0.28 1.7e+02 37 62 .. 70 95 .. 59 99 .. 0.89 3 ? 0.4 0.0 1.8 1e+03 38 61 .. 191 214 .. 187 218 .. 0.88 4 ? -1.6 0.0 7.6 4.4e+03 38 61 .. 231 254 .. 215 267 .. 0.85 5 ? 1.8 0.0 0.66 3.9e+02 37 62 .. 270 295 .. 259 299 .. 0.89 6 ? 3.9 0.0 0.15 85 37 74 .. 350 388 .. 339 400 .. 0.85 7 ? 1.2 0.0 1.1 6.1e+02 35 62 .. 428 455 .. 414 460 .. 0.85 8 ? 1.1 0.0 1.2 6.8e+02 33 58 .. 506 531 .. 479 543 .. 0.82 9 ? -0.8 0.0 4.4 2.5e+03 37 57 .. 550 570 .. 535 575 .. 0.88 10 ? -0.5 0.0 3.6 2.1e+03 37 65 .. 757 786 .. 749 794 .. 0.77 11 ? -1.5 0.0 7.2 4.2e+03 38 61 .. 838 861 .. 820 864 .. 0.84 12 ? -1.3 0.0 6.2 3.6e+03 30 57 .. 910 937 .. 888 942 .. 0.84 13 ? 0.5 0.0 1.7 9.9e+02 33 59 .. 1164 1190 .. 1152 1195 .. 0.84 14 ? -1.1 0.0 5.4 3.1e+03 37 59 .. 1328 1350 .. 1311 1368 .. 0.78 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 7 SHPRH_helical-1st 37 keevaeavekYRevlrlaeenkek 60 k+++++++e Y + l++a e ++ FUN_000362-T1 30 KSDFSKSIECYEKSLKIASEGGDR 53 67999************9997665 PP == domain 2 score: 3.0 bits; conditional E-value: 0.28 SHPRH_helical-1st 37 keevaeavekYRevlrlaeenkekik 62 ++++++a+e Y e l++a+e ++++ FUN_000362-T1 70 QSDFPKAIECYEESLKIAKEAGDRVR 95 789*****************998876 PP == domain 3 score: 0.4 bits; conditional E-value: 1.8 SHPRH_helical-1st 38 eevaeavekYRevlrlaeenkeki 61 +++++a++ Y++ l++a++ +++ FUN_000362-T1 191 SNFPKAIKFYKKSLKIAKKAGDRV 214 789**************9988776 PP == domain 4 score: -1.6 bits; conditional E-value: 7.6 SHPRH_helical-1st 38 eevaeavekYRevlrlaeenkeki 61 +++++++e Y + l +a+e +++ FUN_000362-T1 231 SNFPKSIECYEKSLTIAKEAGDRV 254 7899*************9998876 PP == domain 5 score: 1.8 bits; conditional E-value: 0.66 SHPRH_helical-1st 37 keevaeavekYRevlrlaeenkekik 62 ++++++a+e Y + l++a e ++++ FUN_000362-T1 270 QSDFPKAIECYEKSLKIAREAGDRVR 295 789****************9988876 PP == domain 6 score: 3.9 bits; conditional E-value: 0.15 SHPRH_helical-1st 37 keevaeavekYRevlrlaeenkek.iktDsLqrlHtlhn 74 ++++++ave Y + l++a+e ++ ++ D+ +l l+n FUN_000362-T1 350 QSDFPKAVECYEKSLKIAKEAGDRtLEGDAYLNLGCLYN 388 789***************999876588888877777777 PP == domain 7 score: 1.2 bits; conditional E-value: 1.1 SHPRH_helical-1st 35 iikeevaeavekYRevlrlaeenkekik 62 + ++++++++e Y e l++ e ++++ FUN_000362-T1 428 FSQSNFPKSIECYEETLKIVREAGDRVR 455 56899***************99988876 PP == domain 8 score: 1.1 bits; conditional E-value: 1.2 SHPRH_helical-1st 33 laiikeevaeavekYRevlrlaeenk 58 +++ ++++ +a+e Y e l++a e FUN_000362-T1 506 VYFSQSDFCKAIECYEESLKIAREAG 531 5667899**************98864 PP == domain 9 score: -0.8 bits; conditional E-value: 4.4 SHPRH_helical-1st 37 keevaeavekYRevlrlaeen 57 +++++ a+e Y + l++a e FUN_000362-T1 550 QGDFPIAIECYEKSLKIASEG 570 7899************99885 PP == domain 10 score: -0.5 bits; conditional E-value: 3.6 SHPRH_helical-1st 37 keevaeavekYRevlrlaeenkek.iktDs 65 ++e+ +a++ Y ++l++ +e e+ ++ Ds FUN_000362-T1 757 RSEFRKAIKCYEKALNIFTEVGEQaLEGDS 786 68999***********98886554266665 PP == domain 11 score: -1.5 bits; conditional E-value: 7.2 SHPRH_helical-1st 38 eevaeavekYRevlrlaeenkeki 61 +++++a+e Y + l++a e +k FUN_000362-T1 838 SDLPKAIEYYEKSLNIAREAGDKA 861 57899***********99987765 PP == domain 12 score: -1.3 bits; conditional E-value: 6.2 SHPRH_helical-1st 30 laglaiikeevaeavekYRevlrlaeen 57 l ++++ +++ ++a+e Y + l++a e FUN_000362-T1 910 LGSVYLCRGDRSKAIECYEKSLHIAGEA 937 56788899999***********999886 PP == domain 13 score: 0.5 bits; conditional E-value: 1.7 SHPRH_helical-1st 33 laiikeevaeavekYRevlrlaeenke 59 ++ ++++++a+e Y + l +a e + FUN_000362-T1 1164 VYHFQSDFPKAIECYEKSLDIAREAGD 1190 566899**************9998765 PP == domain 14 score: -1.1 bits; conditional E-value: 5.4 SHPRH_helical-1st 37 keevaeavekYRevlrlaeenke 59 ++++++a+e Y + l++a e + FUN_000362-T1 1328 QSNFSKAIECYEKSLNIAWEAGD 1350 7899***********99877655 PP >> RNPP_C RNPP family C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.6 0.1 0.0058 3.4 85 154 .. 63 130 .. 59 164 .. 0.82 2 ? 1.7 0.1 0.38 2.2e+02 75 153 .. 213 249 .. 182 302 .. 0.49 3 ? 3.6 0.0 0.095 55 85 168 .. 303 384 .. 298 407 .. 0.69 4 ? 3.9 0.0 0.076 44 86 155 .. 424 491 .. 419 511 .. 0.80 5 ! 8.4 0.0 0.0032 1.9 85 165 .. 463 541 .. 458 555 .. 0.87 6 ! 6.9 0.1 0.0092 5.3 87 176 .. 505 599 .. 502 609 .. 0.67 7 ? 2.2 0.2 0.27 1.5e+02 122 189 .. 745 811 .. 724 815 .. 0.80 8 ? 2.1 0.0 0.27 1.6e+02 85 166 .. 870 949 .. 865 970 .. 0.77 9 ? 1.0 0.0 0.59 3.4e+02 123 189 .. 1197 1262 .. 1157 1272 .. 0.52 10 ? 3.6 0.1 0.097 56 85 186 .. 1281 1379 .. 1278 1385 .. 0.74 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0058 RNPP_C 85 lAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiek 154 l vy + + k+ie y++ l + +++ d + k k+ +n + + + d+++s+e ++++k++ e FUN_000362-T1 63 LGRVYDSQSDFPKAIECYEESL-KIAKEAGD-RVRKGKAYFNLGLVFDSQSDFSKSIECYEKSLKIASEG 130 567899999*************.55555555.78999******97766789************9987665 PP == domain 2 score: 1.7 bits; conditional E-value: 0.38 RNPP_C 75 lhlelhiknslAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsie 153 e++ sl vy ++ ksie y++ l +++ e FUN_000362-T1 213 RVREIKAYLSLGRVYDTLSNFPKSIECYEKSL------------------------------------------TIAKE 249 33344444455555555555555555555555..........................................43332 PP == domain 3 score: 3.6 bits; conditional E-value: 0.095 RNPP_C 85 lAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLyd.kndydsslevinqaiklsiekenmsLLGqlyYqra 168 l vy +g + ksie y++ l +++ d + +n + l+yd + d+ +++e ++++k++ e + +L G y + FUN_000362-T1 303 LGLVYGSQGIFGKSIECYEKSL-RIASEGGD-RATEGDAFFNLG-LVYDsQSDFPKAVECYEKSLKIAKEAGDRTLEGDAYLNLG 384 5678999999999999999888.66666666.677888888887.4454156777777777777777776666666666554433 PP == domain 4 score: 3.9 bits; conditional E-value: 0.076 RNPP_C 86 AnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsieke 155 vy + ++ ksie y++ l + + d + k+ +n + + + ++ +s+e ++++k++ e + FUN_000362-T1 424 GLVYFSQSNFPKSIECYEETL-KIVREAGD-RVREGKAYFNLGFVYNSQSEFPKSIECFEKSLKTASEGR 491 678999999***********9.44444444.578899******9999999***********999876655 PP == domain 5 score: 8.4 bits; conditional E-value: 0.0032 RNPP_C 85 lAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyY 165 l vy + ++ ksie +++ l +++++ +d + n +++ + + d+ +++e + ++k++ e n L G y FUN_000362-T1 463 LGFVYNSQSEFPKSIECFEKSL-KTASEGRD-RATEGDAYLNLGRVYFSQSDFCKAIECYEESLKIAREAGNRDLEGDAYL 541 668999**************99.67777777.78999999**************************999999988887664 PP == domain 6 score: 6.9 bits; conditional E-value: 0.0092 RNPP_C 87 nvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydknd.......ydsslevinqaiklsiekenmsLLGqlyYqraeclEkld 175 vy + + k+ie y++ l + + + + +l + n + + y + d y++sl++ ++ + e + LG +yY +++ + + FUN_000362-T1 505 RVYFSQSDFCKAIECYEESL-KIAREAGN-RDLEGDAYLNVGLFFYSQGDfpiaiecYEKSLKIASEGVDWATEGKVYLNLGHVYYSQSDFRKETE 598 67888888899999999877.44433334.667777777777777766552222222677777777777888888888889999999888766655 PP RNPP_C 176 f 176 FUN_000362-T1 599 C 599 5 PP == domain 7 score: 2.2 bits; conditional E-value: 0.27 RNPP_C 122 kvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYqraeclEkldfseeeiaesykkAl 189 + +n + + y + ++ ++++ ++a+++ e + +L G y + ++ k + ++ + e y+k l FUN_000362-T1 745 RFYFNLGVVYYSRSEFRKAIKCYEKALNIFTEVGEQALEGDSYLKLGNAY-KSHNDFPKAIECYEKSL 811 6789999999*******************999999999999998888765.44445555566666665 PP == domain 8 score: 2.1 bits; conditional E-value: 0.27 RNPP_C 85 lAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYq 166 l n y +++ k+ + y++ l + + + d k++Yn + + + d ++++e +++++++ e + + G+ y+ FUN_000362-T1 870 LGNAYMSHDESPKAFNCYEKSL-NIAREAGD-RATEGKANYNLGSVYLCRGDRSKAIECYEKSLHIAGEAGDGTTEGKAYFT 949 5677778888888999999988.66665556.78999*********9999*********99999987666555555555554 PP == domain 9 score: 1.0 bits; conditional E-value: 0.59 RNPP_C 123 vlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYqraeclEkldfseeeiaesykkAl 189 +n + + +nd+ +++e +++++++ e+ + + G+ y + + + + ++ + e y+k l FUN_000362-T1 1197 GYFNLGTVYKSRNDLPKAIEFYEKSLNIAREEGDWAREGKAYLNLGLVYD-SQSDFRNAIECYEKSL 1262 55555555555555555555555555555555555555555444443332.2334444444444444 PP == domain 10 score: 3.6 bits; conditional E-value: 0.097 RNPP_C 85 lAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGqlyYqraeclEkldfse 178 l vy ++ k++e+y++ l + + d k+ n + + + ++++++e +++++++ e + + G+ y+ + + kl+ ++ FUN_000362-T1 1281 LGTVYKSRNDLPKAMEFYEKSL-NISREAGD-RATEGKACLNLGLIYDSQSNFSKAIECYEKSLNIAWEAGDQATEGKAYFSLGI-VYKLHKDF 1371 5678999999999999999999.44444444.5789999999985444567899*********9999999999988888887663.44555555 PP RNPP_C 179 eeiaesyk 186 + e ++ FUN_000362-T1 1372 AKAFECFE 1379 55555555 PP >> Cerato-platanin Cerato-platanin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 3.4 2e+03 66 105 .. 66 106 .. 35 119 .. 0.78 2 ? 0.2 0.0 1.9 1.1e+03 67 112 .. 187 233 .. 177 241 .. 0.84 3 ? -1.5 0.0 6.6 3.8e+03 75 105 .. 235 266 .. 224 279 .. 0.77 4 ? -1.2 0.0 5.1 3e+03 65 103 .. 265 304 .. 255 312 .. 0.86 5 ? 1.4 0.0 0.82 4.7e+02 66 103 .. 386 424 .. 367 437 .. 0.86 6 ? -0.4 0.0 3 1.7e+03 65 103 .. 832 871 .. 827 886 .. 0.81 7 ? -0.8 0.0 4 2.3e+03 81 105 .. 888 913 .. 874 926 .. 0.83 8 ? 1.9 0.0 0.58 3.3e+02 64 102 .. 951 989 .. 930 994 .. 0.85 9 ? 2.6 0.0 0.33 1.9e+02 74 105 .. 1132 1164 .. 1108 1202 .. 0.88 10 ? 6.7 0.1 0.019 11 64 105 .. 1322 1364 .. 1303 1377 .. 0.80 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 3.4 Cerato-platanin 66 tyngktiyvlaidaagaGfniakkamdeltngqaa.elGrv 105 y++++ + ai+ + + iak+a d++ +g+a +lG v FUN_000362-T1 66 VYDSQSDFPKAIECYEESLKIAKEAGDRVRKGKAYfNLGLV 106 47778888889999999999999999999998884356655 PP == domain 2 score: 0.2 bits; conditional E-value: 1.9 Cerato-platanin 67 yngktiyvlaidaagaGfniakkamdeltngqaa.elGrvdaeveev 112 y++++ + ai + + iakka d++ + +a +lGrv ++ + FUN_000362-T1 187 YDSESNFPKAIKFYKKSLKIAKKAGDRVREIKAYlSLGRVYDTLSNF 233 7888888899999999*************9998549***98777665 PP == domain 3 score: -1.5 bits; conditional E-value: 6.6 Cerato-platanin 75 laidaagaGfniakkamdeltngqaa.elGrv 105 +i+ + + iak+a d++t+g a +lG v FUN_000362-T1 235 KSIECYEKSLTIAKEAGDRVTEGDAYlNLGLV 266 56777788899***********9985366655 PP == domain 4 score: -1.2 bits; conditional E-value: 5.1 Cerato-platanin 65 ityngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 + y++++ + ai+ + + ia++a d++ +g+a +lG FUN_000362-T1 265 LVYDSQSDFPKAIECYEKSLKIAREAGDRVREGKAYlNLG 304 78999999999*******************9999842555 PP == domain 5 score: 1.4 bits; conditional E-value: 0.82 Cerato-platanin 66 tyngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 yn+++ + ai+ + +nia++a d + +g+a +lG FUN_000362-T1 386 LYNSESDFPKAIECDEKSLNIAREAGDPVREGKAYlNLG 424 699999999*******************99999852566 PP == domain 6 score: -0.4 bits; conditional E-value: 3 Cerato-platanin 65 ityngktiyvlaidaagaGfniakkamdeltngqaa.elG 103 i yn+ + ai+ + +nia++a d+ +g+a +lG FUN_000362-T1 832 IVYNSCSDLPKAIEYYEKSLNIAREAGDKAKEGNAYlNLG 871 677777778889999999**********999998842555 PP == domain 7 score: -0.8 bits; conditional E-value: 4 Cerato-platanin 81 gaGfniakkamdeltngqaa.elGrv 105 + +nia++a d+ t+g+a+ +lG v FUN_000362-T1 888 EKSLNIAREAGDRATEGKANyNLGSV 913 5679************9996356655 PP == domain 8 score: 1.9 bits; conditional E-value: 0.58 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaael 102 ++ y++++ aid + +nia++a d+ ++a+++ FUN_000362-T1 951 GVVYESRCDLTNAIDCYVKSLNIAREAGDRTGVNRANQY 989 68899999999*****************99988888764 PP == domain 9 score: 2.6 bits; conditional E-value: 0.33 Cerato-platanin 74 vlaidaagaGfniakkamdeltngqaa.elGrv 105 ai+ +G+nia++ d+ t+g+a+ +lG v FUN_000362-T1 1132 RKAIECHEKGLNIAREVGDRTTEGKASfHLGTV 1164 56999999***************9986356665 PP == domain 10 score: 6.7 bits; conditional E-value: 0.019 Cerato-platanin 64 kityngktiyvlaidaagaGfniakkamdeltngqaa.elGrv 105 ++ y++++ + ai+ + +nia +a d+ t+g+a +lG v FUN_000362-T1 1322 GLIYDSQSNFSKAIECYEKSLNIAWEAGDQATEGKAYfSLGIV 1364 468*******************************995366655 PP >> Glyoxalase Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 6.3 3.6e+03 11 27 .. 272 288 .. 270 374 .. 0.50 2 ? -1.4 0.0 7.1 4.1e+03 10 24 .. 758 772 .. 750 783 .. 0.85 3 ? 1.9 0.0 0.69 4e+02 9 27 .. 837 855 .. 834 897 .. 0.87 4 ? 4.9 0.0 0.077 45 63 110 .. 1116 1159 .. 1033 1176 .. 0.83 5 ? -0.5 0.0 3.9 2.2e+03 9 26 .. 1168 1185 .. 1160 1199 .. 0.81 6 ? 5.4 0.0 0.057 33 9 26 .. 1208 1225 .. 1200 1238 .. 0.87 7 ? 6.3 0.0 0.029 17 9 33 .. 1288 1324 .. 1281 1397 .. 0.63 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 6.3 Glyoxalase 11 dleksldFYtevLGfkl 27 d +k++++Y++ L FUN_000362-T1 272 DFPKAIECYEKSLKIAR 288 66666666666554333 PP == domain 2 score: -1.4 bits; conditional E-value: 7.1 Glyoxalase 10 gdleksldFYtevLG 24 ++ k++++Y+++L+ FUN_000362-T1 758 SEFRKAIKCYEKALN 772 56789********98 PP == domain 3 score: 1.9 bits; conditional E-value: 0.69 Glyoxalase 9 vgdleksldFYtevLGfkl 27 ++dl+k++++Y++ L+ FUN_000362-T1 837 CSDLPKAIEYYEKSLNIAR 855 58***********999765 PP == domain 4 score: 4.9 bits; conditional E-value: 0.077 Glyoxalase 63 aagegghhiafiafsvddvdaaydrlkaagveivrepgrhgwggrysf 110 + + h++++++s d+ +a + +++g +i re g+++++g++sf FUN_000362-T1 1116 E---AYFHLGAVYLSLSDFRKAIE-CHEKGLNIAREVGDRTTEGKASF 1159 2...257***********999985.99***************999986 PP == domain 5 score: -0.5 bits; conditional E-value: 3.9 Glyoxalase 9 vgdleksldFYtevLGfk 26 +d +k++++Y++ L+ FUN_000362-T1 1168 QSDFPKAIECYEKSLDIA 1185 5899*********99865 PP == domain 6 score: 5.4 bits; conditional E-value: 0.057 Glyoxalase 9 vgdleksldFYtevLGfk 26 +dl+k+++FY++ L+ FUN_000362-T1 1208 RNDLPKAIEFYEKSLNIA 1225 69***********99875 PP == domain 7 score: 6.3 bits; conditional E-value: 0.029 Glyoxalase 9 vgdleksldFYtevLGfklveetd............a 33 +dl+k+++FY++ L+ + + FUN_000362-T1 1288 RNDLPKAMEFYEKSLNISREAGDRategkaclnlglI 1324 58*************9988776665555555555443 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.11 64 7 50 .. 55 98 .. 52 118 .. 0.90 2 ? 1.5 0.0 0.42 2.5e+02 12 51 .. 180 219 .. 173 232 .. 0.85 3 ? 2.1 0.0 0.29 1.7e+02 6 49 .. 254 297 .. 250 306 .. 0.92 4 ? -1.5 0.0 3.6 2.1e+03 7 45 .. 335 373 .. 333 376 .. 0.90 5 ? -2.3 0.0 6.5 3.8e+03 6 48 .. 374 416 .. 369 447 .. 0.85 6 ? -1.8 0.0 4.3 2.5e+03 6 49 .. 414 457 .. 409 476 .. 0.89 7 ? 1.3 0.0 0.49 2.9e+02 7 45 .. 495 533 .. 489 564 .. 0.93 8 ? -1.6 0.0 3.8 2.2e+03 12 54 .. 580 622 .. 574 625 .. 0.86 9 ? 2.5 0.0 0.21 1.2e+02 6 47 .. 821 862 .. 817 866 .. 0.90 10 ? 3.3 0.1 0.12 69 6 46 .. 861 901 .. 856 913 .. 0.91 11 ? -1.6 0.0 3.9 2.3e+03 5 46 .. 940 981 .. 936 992 .. 0.85 12 ? 0.4 0.0 0.92 5.4e+02 5 45 .. 1151 1191 .. 1147 1196 .. 0.91 13 ? -1.3 0.0 3.1 1.8e+03 9 48 .. 1195 1234 .. 1190 1268 .. 0.74 14 ? -1.7 0.0 4 2.3e+03 9 46 .. 1275 1312 .. 1268 1336 .. 0.82 15 ? -0.7 0.0 2 1.2e+03 7 44 .. 1353 1390 .. 1347 1401 .. 0.87 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.11 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarlRkle 50 +e a l+L++++ + d+ +A ++ + +l+ ak ++r+Rk + FUN_000362-T1 55 TEGDAYLNLGRVYDSQSDFPKAIECYEESLKIAKEAGDRVRKGK 98 5778999**********************************976 PP == domain 2 score: 1.5 bits; conditional E-value: 0.42 DUF6377 12 llkLaellyeegdierAykYikvaledakfynarlRklei 51 lk+++++ e ++ +A k+ k +l+ ak+ ++r+R++++ FUN_000362-T1 180 YLKVGRVYDSESNFPKAIKFYKKSLKIAKKAGDRVREIKA 219 56677788889999**********************9986 PP == domain 3 score: 2.1 bits; conditional E-value: 0.29 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlRkl 49 ++e a l+L+ ++ + d+ +A ++ + +l+ a+ ++r+R+ FUN_000362-T1 254 VTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKIAREAGDRVREG 297 6788999**********************************975 PP == domain 4 score: -1.5 bits; conditional E-value: 3.6 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynar 45 +e a ++L+ ++ + d+ +A ++ + +l+ ak ++r FUN_000362-T1 335 TEGDAFFNLGLVYDSQSDFPKAVECYEKSLKIAKEAGDR 373 5778999************************99998877 PP == domain 5 score: -2.3 bits; conditional E-value: 6.5 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlRk 48 t e a l+L+ l+ e d+ +A ++ + +l+ a+ ++ +R+ FUN_000362-T1 374 TLEGDAYLNLGCLYNSESDFPKAIECDEKSLNIAREAGDPVRE 416 5677889999999999999999999999999999988887776 PP == domain 6 score: -1.8 bits; conditional E-value: 4.3 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlRkl 49 ++e a l+L+ +++ + ++ ++ ++ + +l+ + ++r+R+ FUN_000362-T1 414 VREGKAYLNLGLVYFSQSNFPKSIECYEETLKIVREAGDRVREG 457 78999***************************999999999975 PP == domain 7 score: 1.3 bits; conditional E-value: 0.49 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynar 45 +e a l+L+++++ + d+ +A ++ + +l+ a+ ++r FUN_000362-T1 495 TEGDAYLNLGRVYFSQSDFCKAIECYEESLKIAREAGNR 533 688899*************************99988876 PP == domain 8 score: -1.6 bits; conditional E-value: 3.8 DUF6377 12 llkLaellyeegdierAykYikvaledakfynarlRkleisei 54 l+L++++y + d+++ ++ + +l+ ak +++ ++++e+ FUN_000362-T1 580 YLNLGHVYYSQSDFRKETECCENSLSIAKEAGDQAGVTRVNEF 622 579*************************999998877777766 PP == domain 9 score: 2.5 bits; conditional E-value: 0.21 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarlR 47 ++e a ++L+ ++ d+ +A +Y + +l+ a+ +++ + FUN_000362-T1 821 VREGNAFFNLGIVYNSCSDLPKAIEYYEKSLNIAREAGDKAK 862 7999****************************9999887765 PP == domain 10 score: 3.3 bits; conditional E-value: 0.12 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynarl 46 ke a l+L++ ++ + + +A ++ + +l+ a+ ++r FUN_000362-T1 861 AKEGNAYLNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRA 901 6999******************************9999886 PP == domain 11 score: -1.6 bits; conditional E-value: 3.9 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynarl 46 +t+e a ++L+ ++ + d+++A + +l+ a+ ++r FUN_000362-T1 940 GTTEGKAYFTLGVVYESRCDLTNAIDCYVKSLNIAREAGDRT 981 688999999999999999999999999999999999888775 PP == domain 12 score: 0.4 bits; conditional E-value: 0.92 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 t+e a ++L+++++ + d+ +A ++ + +l+ a+ ++r FUN_000362-T1 1151 RTTEGKASFHLGTVYHFQSDFPKAIECYEKSLDIAREAGDR 1191 688999*****************************998887 PP == domain 13 score: -1.3 bits; conditional E-value: 3.1 DUF6377 9 naallkLaellyeegdierAykYikvaledakfynarlRk 48 + ++L++++ ++d+ +A ++ + +l+ a+ ++ R+ FUN_000362-T1 1195 GSGYFNLGTVYKSRNDLPKAIEFYEKSLNIAREEGDWARE 1234 5566788888888888888988888888888776665554 PP == domain 14 score: -1.7 bits; conditional E-value: 4 DUF6377 9 naallkLaellyeegdierAykYikvaledakfynarl 46 + ++L++++ ++d+ +A ++ + +l+ + ++r FUN_000362-T1 1275 GSGYFNLGTVYKSRNDLPKAMEFYEKSLNISREAGDRA 1312 5667899999999**************99888888776 PP == domain 15 score: -0.7 bits; conditional E-value: 2 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfyna 44 +e a ++L+ ++ ++d+ +A ++ + +l+ a+ ++ FUN_000362-T1 1353 TEGKAYFSLGIVYKLHKDFAKAFECFEKSLNIAREAGD 1390 6889999***99999***************99988776 PP >> AimR AimR transcriptional regulator-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.1 0.84 4.9e+02 170 201 .. 59 91 .. 29 129 .. 0.59 2 ? -0.4 0.1 1.2 7e+02 156 199 .. 205 249 .. 183 272 .. 0.65 3 ? 0.3 0.0 0.75 4.4e+02 152 200 .. 238 290 .. 212 302 .. 0.65 4 ? -1.8 0.0 3.2 1.8e+03 172 205 .. 341 375 .. 317 410 .. 0.67 5 ? -0.1 0.0 1 5.8e+02 149 221 .. 398 474 .. 387 490 .. 0.68 6 ? 0.7 0.0 0.58 3.4e+02 169 201 .. 498 531 .. 475 543 .. 0.77 7 ! 8.2 0.2 0.0029 1.7 132 199 .. 745 816 .. 741 830 .. 0.86 8 ! 8.1 0.2 0.003 1.8 145 219 .. 838 917 .. 825 939 .. 0.75 9 ? 3.9 0.0 0.059 34 165 200 .. 1112 1148 .. 1106 1159 .. 0.85 10 ? 1.3 0.0 0.37 2.2e+02 170 201 .. 1157 1189 .. 1152 1198 .. 0.85 11 ? -1.1 0.0 2 1.1e+03 139 199 .. 1203 1267 .. 1197 1288 .. 0.76 12 ! 7.5 0.2 0.0049 2.9 144 216 .. 1328 1404 .. 1315 1408 .. 0.81 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.84 AimR 170 shltlGnSY.lfesYekamkyfekalkiaknee 201 ++l+lG+ Y +++ ka++ +e++lkiak++ FUN_000362-T1 59 AYLNLGRVYdSQSDFPKAIECYEESLKIAKEAG 91 566666666334566666666666666666432 PP == domain 2 score: -0.4 bits; conditional E-value: 1.2 AimR 156 kviensnnprfkalshltlGnSY.lfesYekamkyfekalkiakn 199 k+ ++ + + ++l+lG+ Y +++ k+++ +ek+l iak+ FUN_000362-T1 205 KIAKKAGDRVREIKAYLSLGRVYdTLSNFPKSIECYEKSLTIAKE 249 223333333445667777777776677777777777777777775 PP == domain 3 score: 0.3 bits; conditional E-value: 0.75 AimR 152 kyakkviensnnprfkal...shltlGnSY.lfesYekamkyfekalkiakne 200 ++++k ++ ++++ ++ ++l+lG+ Y +++ ka++ +ek+lkia+++ FUN_000362-T1 238 ECYEKSLTIAKEAGDRVTegdAYLNLGLVYdSQSDFPKAIECYEKSLKIAREA 290 34444444444333333333388888888844678999999999999998864 PP == domain 4 score: -1.8 bits; conditional E-value: 3.2 AimR 172 ltlGnSY.lfesYekamkyfekalkiakneekkel 205 ++lG+ Y +++ ka + +ek+lkiak++ + +l FUN_000362-T1 341 FNLGLVYdSQSDFPKAVECYEKSLKIAKEAGDRTL 375 55666553347899999999*****9997654332 PP == domain 5 score: -0.1 bits; conditional E-value: 1 AimR 149 earkyakkviensnnprfkalshltlGnSYlf.esYekamkyfekalkiak...neekkelvkrtieflnnywgken 221 e+ + + ++ + p+ ++l+lG+ Y+ +++ k+++ +e+ lki++ ++ ++ ++ ++ f++n + + FUN_000362-T1 398 ECDEKSLNIAREAGDPVREGKAYLNLGLVYFSqSNFPKSIECYEETLKIVReagDRVREGKAYFNLGFVYNSQSEFP 474 55666666666666677777789999999986256999999999999999833323344445566666666655554 PP == domain 6 score: 0.7 bits; conditional E-value: 0.58 AimR 169 lshltlGnSYlf.esYekamkyfekalkiaknee 201 ++l+lG+ Y+ +++ ka++ +e++lkia+++ FUN_000362-T1 498 DAYLNLGRVYFSqSDFCKAIECYEESLKIAREAG 531 589*******85379***************9654 PP == domain 7 score: 8.2 bits; conditional E-value: 0.0029 AimR 132 Rlsellfnvllnrneleearkyakkviensnnprfkal...shltlGnSYl.fesYekamkyfekalkiakn 199 R++ +l v++ r+e +a k+++k+++ ++ + +al s+l+lGn Y ++ ka++ +ek+l ia++ FUN_000362-T1 745 RFYFNLGVVYYSRSEFRKAIKCYEKALNIFTEVGEQALegdSYLKLGNAYKsHNDFPKAIECYEKSLIIARR 816 88889999*******************99887777776666*********75799**********9988875 PP == domain 8 score: 8.1 bits; conditional E-value: 0.003 AimR 145 neleearkyakkviensnnprfkal...shltlGnSYl.fesYekamkyfekalkiakne.ekkelvkrtieflnnywgk 219 ++l +a +y++k ++ +++ ka ++l+lGn Y+ ++ ka + +ek+l+ia+++ +++++ k ++++ ++y ++ FUN_000362-T1 838 SDLPKAIEYYEKSLNIAREAGDKAKegnAYLNLGNAYMsHDESPKAFNCYEKSLNIAREAgDRATEGKANYNLGSVYLCR 917 6777888999999998887776665555**********44556677888********97625667778888887777765 PP == domain 9 score: 3.9 bits; conditional E-value: 0.059 AimR 165 rfkalshltlGnSYl.fesYekamkyfekalkiakne 200 ++ka ++++lG Yl +++ ka++ ek+l+ia++ FUN_000362-T1 1112 ATKAEAYFHLGAVYLsLSDFRKAIECHEKGLNIAREV 1148 68999*********979****************9853 PP == domain 10 score: 1.3 bits; conditional E-value: 0.37 AimR 170 shltlGnSYlf.esYekamkyfekalkiaknee 201 + ++lG+ Y f +++ ka++ +ek+l+ia+++ FUN_000362-T1 1157 ASFHLGTVYHFqSDFPKAIECYEKSLDIAREAG 1189 6799******9568***************9754 PP == domain 11 score: -1.1 bits; conditional E-value: 2 AimR 139 nvllnrneleearkyakkviensnnprfkal...shltlGnSY.lfesYekamkyfekalkiakn 199 v+ rn+l +a + ++k ++ +++ a ++l+lG+ Y +++ +a++ +ek+l ia + FUN_000362-T1 1203 TVYKSRNDLPKAIEFYEKSLNIAREEGDWARegkAYLNLGLVYdSQSDFRNAIECYEKSLLIATK 1267 56777888888888888888888877765544558999999884567899999999988877754 PP == domain 12 score: 7.5 bits; conditional E-value: 0.0049 AimR 144 rneleearkyakkviensnnprfkal...shltlGnSY.lfesYekamkyfekalkiakneekkelvkrtieflnny 216 +++ ++a ++++k ++ +++ +a+ ++++lG Y l +++ka + fek+l+ia+++ ++ v+r+ ++l+n FUN_000362-T1 1328 QSNFSKAIECYEKSLNIAWEAGDQATegkAYFSLGIVYkLHKDFAKAFECFEKSLNIAREAGDHAGVSRANQYLANS 1404 56667777777777777776666666666*********5568*******************9999999998888875 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.37 2.1e+02 131 153 .] 62 84 .. 54 89 .. 0.87 2 ? -1.6 0.0 6.8 4e+03 14 28 .. 152 166 .. 143 170 .. 0.73 3 ? 5.9 0.1 0.034 20 4 32 .. 182 210 .. 180 255 .. 0.82 4 ? -1.3 0.0 5.6 3.2e+03 132 153 .] 263 284 .. 257 284 .. 0.82 5 ? -1.2 0.0 5.1 3e+03 14 26 .. 352 364 .. 341 374 .. 0.60 6 ? 2.9 0.0 0.28 1.6e+02 131 153 .] 502 524 .. 486 530 .. 0.80 7 ? 1.5 0.0 0.79 4.6e+02 132 153 .] 750 771 .. 733 775 .. 0.76 8 ? 2.6 0.0 0.36 2.1e+02 4 25 .. 789 810 .. 786 816 .. 0.61 9 ? 2.0 0.0 0.54 3.1e+02 12 30 .. 837 855 .. 829 872 .. 0.79 10 ? -1.5 0.0 6.5 3.8e+03 112 151 .. 1101 1140 .. 1097 1142 .. 0.77 11 ? -0.3 0.0 2.7 1.6e+03 129 153 .] 1158 1182 .. 1145 1182 .. 0.85 12 ? 0.2 0.0 2 1.2e+03 16 26 .. 1212 1222 .. 1199 1229 .. 0.54 13 ? -1.3 0.0 5.7 3.3e+03 132 153 .] 1241 1262 .. 1236 1262 .. 0.83 14 ? -1.6 0.0 7 4.1e+03 131 153 .] 1280 1302 .. 1278 1302 .. 0.84 15 ? 3.4 0.1 0.21 1.2e+02 126 153 .] 1315 1342 .. 1287 1342 .. 0.84 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.37 ARM_TT21_4th 131 qlAehaaserdyekaiklYkeAL 153 +l++ + s++d+ kai++Y e+L FUN_000362-T1 62 NLGRVYDSQSDFPKAIECYEESL 84 67888899999999999999987 PP == domain 2 score: -1.6 bits; conditional E-value: 6.8 ARM_TT21_4th 14 qYkkAinYYeaalks 28 +++k i++Ye+ lk+ FUN_000362-T1 152 DFAKPIQFYEKSLKI 166 577778888887776 PP == domain 3 score: 5.9 bits; conditional E-value: 0.034 ARM_TT21_4th 4 kiGqalvktHqYkkAinYYeaalksseqk 32 k+G+ + ++ kAi++Y++ lk+ +++ FUN_000362-T1 182 KVGRVYDSESNFPKAIKFYKKSLKIAKKA 210 788888888899**********9988765 PP == domain 4 score: -1.3 bits; conditional E-value: 5.6 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s++d+ kai++Y +L FUN_000362-T1 263 LGLVYDSQSDFPKAIECYEKSL 284 5667889999999999998876 PP == domain 5 score: -1.2 bits; conditional E-value: 5.1 ARM_TT21_4th 14 qYkkAinYYeaal 26 ++ kA++ Ye+ l FUN_000362-T1 352 DFPKAVECYEKSL 364 3455555555555 PP == domain 6 score: 2.9 bits; conditional E-value: 0.28 ARM_TT21_4th 131 qlAehaaserdyekaiklYkeAL 153 +l++ + s++d+ kai++Y e+L FUN_000362-T1 502 NLGRVYFSQSDFCKAIECYEESL 524 56777778888888888888876 PP == domain 7 score: 1.5 bits; conditional E-value: 0.79 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s++++ kaik+Y AL FUN_000362-T1 750 LGVVYYSRSEFRKAIKCYEKAL 771 5556667777777777777776 PP == domain 8 score: 2.6 bits; conditional E-value: 0.36 ARM_TT21_4th 4 kiGqalvktHqYkkAinYYeaa 25 k+G+a+ ++ kAi+ Ye+ FUN_000362-T1 789 KLGNAYKSHNDFPKAIECYEKS 810 5566664444566666666654 PP == domain 9 score: 2.0 bits; conditional E-value: 0.54 ARM_TT21_4th 12 tHqYkkAinYYeaalksse 30 + + kAi+YYe+ l++ + FUN_000362-T1 837 CSDLPKAIEYYEKSLNIAR 855 556679*******998765 PP == domain 10 score: -1.5 bits; conditional E-value: 6.5 ARM_TT21_4th 112 veqpdaveeqkklaakiclqlAehaaserdyekaiklYke 151 +e+++ + +++ a+ ++l+ + s +d+ kai+++ FUN_000362-T1 1101 IETEEDYAGDRATKAEAYFHLGAVYLSLSDFRKAIECHEK 1140 5666666677777888888999999999999999998866 PP == domain 11 score: -0.3 bits; conditional E-value: 2.7 ARM_TT21_4th 129 clqlAehaaserdyekaiklYkeAL 153 +++l+ ++ ++d+ kai++Y +L FUN_000362-T1 1158 SFHLGTVYHFQSDFPKAIECYEKSL 1182 67889999999**********9876 PP == domain 12 score: 0.2 bits; conditional E-value: 2 ARM_TT21_4th 16 kkAinYYeaal 26 kAi++Ye+ l FUN_000362-T1 1212 PKAIEFYEKSL 1222 35555555555 PP == domain 13 score: -1.3 bits; conditional E-value: 5.7 ARM_TT21_4th 132 lAehaaserdyekaiklYkeAL 153 l+ + s++d+ +ai++Y +L FUN_000362-T1 1241 LGLVYDSQSDFRNAIECYEKSL 1262 56678899**********9876 PP == domain 14 score: -1.6 bits; conditional E-value: 7 ARM_TT21_4th 131 qlAehaaserdyekaiklYkeAL 153 +l+ + s++d+ ka+++Y +L FUN_000362-T1 1280 NLGTVYKSRNDLPKAMEFYEKSL 1302 67888999999999999998776 PP == domain 15 score: 3.4 bits; conditional E-value: 0.21 ARM_TT21_4th 126 akiclqlAehaaserdyekaiklYkeAL 153 k cl+l+ + s+++++kai++Y +L FUN_000362-T1 1315 GKACLNLGLIYDSQSNFSKAIECYEKSL 1342 57799*******************9876 PP >> Ulvan_lyase_2nd Endo-acting ulvan lyase 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 1.7 1e+03 66 113 .. 30 77 .. 29 93 .. 0.81 2 ? 1.7 0.0 0.58 3.4e+02 64 112 .. 108 156 .. 104 169 .. 0.88 3 ? 0.6 0.0 1.3 7.5e+02 64 104 .. 188 228 .. 184 249 .. 0.87 4 ? 0.6 0.0 1.3 7.4e+02 64 113 .. 268 317 .. 262 326 .. 0.89 5 ? 2.3 0.0 0.39 2.3e+02 64 113 .. 348 397 .. 345 407 .. 0.86 6 ? 1.1 0.0 0.91 5.3e+02 69 109 .. 513 553 .. 509 569 .. 0.83 7 ? 0.9 0.1 1.1 6.2e+02 67 121 .. 591 645 .. 588 651 .. 0.86 8 ? 3.3 0.0 0.19 1.1e+02 70 114 .. 881 925 .. 865 934 .. 0.87 9 ? -0.9 0.0 3.6 2.1e+03 75 113 .. 1217 1255 .. 1208 1281 .. 0.59 10 ? -0.6 0.0 3 1.7e+03 73 114 .. 1295 1336 .. 1287 1348 .. 0.78 11 ? 0.0 0.0 1.9 1.1e+03 64 99 .. 1326 1361 .. 1322 1377 .. 0.88 12 ? -1.0 0.0 4 2.3e+03 66 106 .. 1368 1408 .. 1366 1411 .] 0.88 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 1.7 Ulvan_lyase_2nd 66 hrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 + ++ ++ e ye l++a+ g ++ e +a +L + yd++ ++ +ai FUN_000362-T1 30 KSDFSKSIECYEKSLKIASEGGDRATEGDAYLNLGRVYDSQSDFPKAI 77 677888999999999999999999999999999999998887766655 PP == domain 2 score: 1.7 bits; conditional E-value: 0.58 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpa 112 Ds+ ++ ++ e ye l++a+ g + e +a +L++ y+++ ++ + FUN_000362-T1 108 DSQSDFSKSIECYEKSLKIASEGGDWATEGDAYLNLRRVYESQSDFAKP 156 9999**********************************99988776655 PP == domain 3 score: 0.6 bits; conditional E-value: 1.3 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqayd 104 Ds+ ++ + ++y+ l++ak+ g + e ka L + yd FUN_000362-T1 188 DSESNFPKAIKFYKKSLKIAKKAGDRVREIKAYLSLGRVYD 228 899999999**************999999888888887776 PP == domain 4 score: 0.6 bits; conditional E-value: 1.3 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Ds+ ++ + e ye l++a+ g + e ka +L y ++G + ++i FUN_000362-T1 268 DSQSDFPKAIECYEKSLKIAREAGDRVREGKAYLNLGLVYGSQGIFGKSI 317 899999999**********************9999999999999877766 PP == domain 5 score: 2.3 bits; conditional E-value: 0.39 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 Ds+ ++ + e ye l++ak g ++le +a +L y++e ++ +ai FUN_000362-T1 348 DSQSDFPKAVECYEKSLKIAKEAGDRTLEGDAYLNLGCLYNSESDFPKAI 397 8999999999**********************999999888776666655 PP == domain 6 score: 1.1 bits; conditional E-value: 0.91 Ulvan_lyase_2nd 69 ndeteelyelalnlakrkgyteleekaealLkqaydaeGgy 109 + + e ye l++a+ g+++le +a ++ +++++G++ FUN_000362-T1 513 FCKAIECYEESLKIAREAGNRDLEGDAYLNVGLFFYSQGDF 553 5667799******************9999998888888876 PP == domain 7 score: 0.9 bits; conditional E-value: 1.1 Ulvan_lyase_2nd 67 rkndeteelyelalnlakrkgyteleekaealLkqaydaeGgykpaiktstleyn 121 +++++ e e l++ak g ++ +++++ L +y a G+ ++a+ ++ ++n FUN_000362-T1 591 SDFRKETECCENSLSIAKEAGDQAGVTRVNEFLLDSYTALGNSSKAFINRIENQN 645 6788899999*********************************999877665554 PP == domain 8 score: 3.3 bits; conditional E-value: 0.19 Ulvan_lyase_2nd 70 deteelyelalnlakrkgyteleekaealLkqaydaeGgykpaik 114 + + ye ln+a+ g ++ e ka+ +L + y +G+ ++ai+ FUN_000362-T1 881 PKAFNCYEKSLNIAREAGDRATEGKANYNLGSVYLCRGDRSKAIE 925 555678********************************9999885 PP == domain 9 score: -0.9 bits; conditional E-value: 3.6 Ulvan_lyase_2nd 75 lyelalnlakrkgyteleekaealLkqaydaeGgykpai 113 +ye ln+a+ +g + e ka +L yd++ ++++ai FUN_000362-T1 1217 FYEKSLNIAREEGDWAREGKAYLNLGLVYDSQSDFRNAI 1255 556666666666655555555555555555544444333 PP == domain 10 score: -0.6 bits; conditional E-value: 3 Ulvan_lyase_2nd 73 eelyelalnlakrkgyteleekaealLkqaydaeGgykpaik 114 e+ye ln+++ g ++ e ka +L +yd++ ++++ai+ FUN_000362-T1 1295 MEFYEKSLNISREAGDRATEGKACLNLGLIYDSQSNFSKAIE 1336 678999999999999999999999999999988888777764 PP == domain 11 score: 0.0 bits; conditional E-value: 1.9 Ulvan_lyase_2nd 64 DshrkndeteelyelalnlakrkgyteleekaealL 99 Ds+ ++ + e ye ln+a g ++ e ka L FUN_000362-T1 1326 DSQSNFSKAIECYEKSLNIAWEAGDQATEGKAYFSL 1361 9999******************99999998887666 PP == domain 12 score: -1.0 bits; conditional E-value: 4 Ulvan_lyase_2nd 66 hrkndeteelyelalnlakrkgyteleekaealLkqaydae 106 h+++ + e +e ln+a+ g ++ +a+++L+++y FUN_000362-T1 1368 HKDFAKAFECFEKSLNIAREAGDHAGVSRANQYLANSYLVP 1408 7788888999************************9999655 PP >> HTH_Tnp_Mu_2 Mu DNA binding, I gamma subdomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.84 4.9e+02 48 69 .. 72 93 .. 38 102 .. 0.79 2 ? -0.1 0.0 2.4 1.4e+03 50 69 .. 234 253 .. 202 258 .. 0.83 3 ? 1.7 0.0 0.67 3.9e+02 48 69 .. 272 293 .. 256 299 .. 0.81 4 ? 1.3 0.0 0.88 5.1e+02 48 67 .. 352 371 .. 337 376 .. 0.85 5 ? -0.3 0.0 2.8 1.6e+03 43 69 .. 426 453 .. 414 461 .. 0.77 6 ? -0.3 0.0 2.8 1.6e+03 36 67 .. 499 531 .. 485 535 .. 0.73 7 ? -0.8 0.0 3.9 2.3e+03 58 68 .. 522 532 .. 511 572 .. 0.55 8 ? -1.2 0.0 5.2 3e+03 33 67 .. 783 818 .. 764 822 .. 0.77 9 ? 6.2 0.0 0.026 15 34 67 .. 864 898 .. 847 906 .. 0.84 10 ? 0.9 0.0 1.1 6.6e+02 45 67 .. 1167 1189 .. 1142 1194 .. 0.84 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.84 HTH_Tnp_Mu_2 48 ekPtlaacyerlekaAqekGwa 69 + P +cye k+A+e+G + FUN_000362-T1 72 DFPKAIECYEESLKIAKEAGDR 93 4588899***********9966 PP == domain 2 score: -0.1 bits; conditional E-value: 2.4 HTH_Tnp_Mu_2 50 PtlaacyerlekaAqekGwa 69 P +cye+ ++A+e+G + FUN_000362-T1 234 PKSIECYEKSLTIAKEAGDR 253 66678***********9965 PP == domain 3 score: 1.7 bits; conditional E-value: 0.67 HTH_Tnp_Mu_2 48 ekPtlaacyerlekaAqekGwa 69 + P +cye+ k+A+e+G + FUN_000362-T1 272 DFPKAIECYEKSLKIAREAGDR 293 4588889************965 PP == domain 4 score: 1.3 bits; conditional E-value: 0.88 HTH_Tnp_Mu_2 48 ekPtlaacyerlekaAqekG 67 + P +cye+ k+A+e+G FUN_000362-T1 352 DFPKAVECYEKSLKIAKEAG 371 4588889***********99 PP == domain 5 score: -0.3 bits; conditional E-value: 2.8 HTH_Tnp_Mu_2 43 dYlrpek.PtlaacyerlekaAqekGwa 69 Y+++++ P +cye + k+ +e+G + FUN_000362-T1 426 VYFSQSNfPKSIECYEETLKIVREAGDR 453 5666543388999***********9965 PP == domain 6 score: -0.3 bits; conditional E-value: 2.8 HTH_Tnp_Mu_2 36 awqflkadYlrpekP.tlaacyerlekaAqekG 67 a+ l Y++++ +cye k+A+e+G FUN_000362-T1 499 AYLNLGRVYFSQSDFcKAIECYEESLKIAREAG 531 55566666666655313458***********99 PP == domain 7 score: -0.8 bits; conditional E-value: 3.9 HTH_Tnp_Mu_2 58 rlekaAqekGw 68 k+A+e+G FUN_000362-T1 522 ESLKIAREAGN 532 55555555542 PP == domain 8 score: -1.2 bits; conditional E-value: 5.2 HTH_Tnp_Mu_2 33 deeawqflkadYlrp.ekPtlaacyerlekaAqekG 67 + + + l + Y ++ + P +cye+ +A+ +G FUN_000362-T1 783 EGDSYLKLGNAYKSHnDFPKAIECYEKSLIIARRAG 818 55566666677766415699999****999999988 PP == domain 9 score: 6.2 bits; conditional E-value: 0.026 HTH_Tnp_Mu_2 34 eeawqflkadYlr.pekPtlaacyerlekaAqekG 67 +a+ l + Y++ +e P +cye+ ++A+e+G FUN_000362-T1 864 GNAYLNLGNAYMShDESPKAFNCYEKSLNIAREAG 898 57888999999973689****************99 PP == domain 10 score: 0.9 bits; conditional E-value: 1.1 HTH_Tnp_Mu_2 45 lrpekPtlaacyerlekaAqekG 67 ++++ P +cye+ +A+e+G FUN_000362-T1 1167 FQSDFPKAIECYEKSLDIAREAG 1189 566779999************99 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.83 4.8e+02 14 30 .. 70 86 .. 61 90 .. 0.83 2 ? -1.1 0.0 3.3 1.9e+03 20 34 .. 109 123 .. 108 126 .. 0.72 3 ? 5.7 0.0 0.025 14 15 30 .. 191 206 .. 189 210 .. 0.91 4 ? -1.2 0.0 3.7 2.2e+03 15 30 .. 231 246 .. 230 249 .. 0.89 5 ? 2.1 0.0 0.35 2e+02 14 31 .. 270 287 .. 268 291 .. 0.83 6 ? 2.0 0.0 0.35 2.1e+02 14 30 .. 350 366 .. 349 371 .. 0.86 7 ? -0.6 0.0 2.4 1.4e+03 10 30 .. 426 446 .. 420 450 .. 0.78 8 ? 1.2 0.1 0.63 3.7e+02 4 34 .. 500 530 .. 498 534 .. 0.80 9 ? -2.2 0.0 7.5 4.4e+03 17 30 .. 553 566 .. 550 567 .. 0.86 10 ? 1.7 0.0 0.44 2.6e+02 15 34 .. 758 777 .. 753 780 .. 0.83 11 ? -0.9 0.0 3 1.7e+03 20 30 .. 843 853 .. 838 857 .. 0.76 12 ? 1.4 0.0 0.56 3.2e+02 15 31 .. 1169 1185 .. 1167 1189 .. 0.84 13 ? -1.8 0.0 5.4 3.2e+03 20 30 .. 1214 1224 .. 1210 1227 .. 0.64 14 ? -1.0 0.0 3.1 1.8e+03 20 34 .. 1247 1261 .. 1246 1264 .. 0.74 15 ? 5.3 0.0 0.033 19 14 30 .. 1328 1344 .. 1327 1346 .. 0.94 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.83 SHNi-TPR 14 nenFeqAvkDlrkaLeL 30 ++ F+ A++ ++++L++ FUN_000362-T1 70 QSDFPKAIECYEESLKI 86 56688999999999987 PP == domain 2 score: -1.1 bits; conditional E-value: 3.3 SHNi-TPR 20 AvkDlrkaLeLreel 34 ++D+ k++e +e+ FUN_000362-T1 109 SQSDFSKSIECYEKS 123 678888888877765 PP == domain 3 score: 5.7 bits; conditional E-value: 0.025 SHNi-TPR 15 enFeqAvkDlrkaLeL 30 +nF+ A+k ++k+L++ FUN_000362-T1 191 SNFPKAIKFYKKSLKI 206 8*************98 PP == domain 4 score: -1.2 bits; conditional E-value: 3.7 SHNi-TPR 15 enFeqAvkDlrkaLeL 30 +nF+ ++ ++k+L + FUN_000362-T1 231 SNFPKSIECYEKSLTI 246 79******9****987 PP == domain 5 score: 2.1 bits; conditional E-value: 0.35 SHNi-TPR 14 nenFeqAvkDlrkaLeLr 31 ++ F+ A++ ++k+L++ FUN_000362-T1 270 QSDFPKAIECYEKSLKIA 287 5679999999*****995 PP == domain 6 score: 2.0 bits; conditional E-value: 0.35 SHNi-TPR 14 nenFeqAvkDlrkaLeL 30 ++ F+ Av+ ++k+L++ FUN_000362-T1 350 QSDFPKAVECYEKSLKI 366 567999*********98 PP == domain 7 score: -0.6 bits; conditional E-value: 2.4 SHNi-TPR 10 iSLEnenFeqAvkDlrkaLeL 30 + ++++nF+ ++ +++ L++ FUN_000362-T1 426 VYFSQSNFPKSIECYEETLKI 446 5678999*9999999998887 PP == domain 8 score: 1.2 bits; conditional E-value: 0.63 SHNi-TPR 4 ydlLGEiSLEnenFeqAvkDlrkaLeLreel 34 y LG + ++++ F A++ ++++L++ +e FUN_000362-T1 500 YLNLGRVYFSQSDFCKAIECYEESLKIAREA 530 66777788889999999999*****997775 PP == domain 9 score: -2.2 bits; conditional E-value: 7.5 SHNi-TPR 17 FeqAvkDlrkaLeL 30 F+ A++ ++k+L++ FUN_000362-T1 553 FPIAIECYEKSLKI 566 7889999*****98 PP == domain 10 score: 1.7 bits; conditional E-value: 0.44 SHNi-TPR 15 enFeqAvkDlrkaLeLreel 34 + F A+k ++kaL++ +e+ FUN_000362-T1 758 SEFRKAIKCYEKALNIFTEV 777 679999*********97776 PP == domain 11 score: -0.9 bits; conditional E-value: 3 SHNi-TPR 20 AvkDlrkaLeL 30 A++ ++k+L++ FUN_000362-T1 843 AIEYYEKSLNI 853 77889999998 PP == domain 12 score: 1.4 bits; conditional E-value: 0.56 SHNi-TPR 15 enFeqAvkDlrkaLeLr 31 + F+ A++ ++k+L++ FUN_000362-T1 1169 SDFPKAIECYEKSLDIA 1185 66999*********995 PP == domain 13 score: -1.8 bits; conditional E-value: 5.4 SHNi-TPR 20 AvkDlrkaLeL 30 A++ ++k+L++ FUN_000362-T1 1214 AIEFYEKSLNI 1224 55557777776 PP == domain 14 score: -1.0 bits; conditional E-value: 3.1 SHNi-TPR 20 AvkDlrkaLeLreel 34 ++D+r a+e +e+ FUN_000362-T1 1247 SQSDFRNAIECYEKS 1261 678899888877775 PP == domain 15 score: 5.3 bits; conditional E-value: 0.033 SHNi-TPR 14 nenFeqAvkDlrkaLeL 30 ++nF+ A++ ++k+L++ FUN_000362-T1 1328 QSNFSKAIECYEKSLNI 1344 79**************8 PP >> Sec8_N Exocyst complex component Sec8 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 6.2 3.6e+03 62 92 .. 68 98 .. 65 102 .. 0.85 2 ? 3.4 0.0 0.16 91 62 96 .. 188 222 .. 184 227 .. 0.89 3 ? 0.1 0.0 1.7 9.8e+02 60 95 .. 266 301 .. 264 303 .. 0.87 4 ? 1.6 0.0 0.56 3.3e+02 65 92 .. 431 458 .. 426 463 .. 0.88 5 ? -0.5 0.0 2.6 1.5e+03 62 86 .. 755 779 .. 751 786 .. 0.81 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 6.2 Sec8_N 62 ehhqaFnssiasYskilssiqesqekvselK 92 + + +F ++i Y++ l+ +e+ ++v++ K FUN_000362-T1 68 DSQSDFPKAIECYEESLKIAKEAGDRVRKGK 98 56789*************9999999998755 PP == domain 2 score: 3.4 bits; conditional E-value: 0.16 Sec8_N 62 ehhqaFnssiasYskilssiqesqekvselKesle 96 + F ++i+ Y+k l+ +++ ++v+e+K l+ FUN_000362-T1 188 DSESNFPKAIKFYKKSLKIAKKAGDRVREIKAYLS 222 56678**************************9875 PP == domain 3 score: 0.1 bits; conditional E-value: 1.7 Sec8_N 60 vnehhqaFnssiasYskilssiqesqekvselKesl 95 v + + +F ++i Y+k l+ e+ ++v+e K l FUN_000362-T1 266 VYDSQSDFPKAIECYEKSLKIAREAGDRVREGKAYL 301 5677889********************999988766 PP == domain 4 score: 1.6 bits; conditional E-value: 0.56 Sec8_N 65 qaFnssiasYskilssiqesqekvselK 92 F +si Y+++l+ + e+ ++v+e K FUN_000362-T1 431 SNFPKSIECYEETLKIVREAGDRVREGK 458 5799******************999876 PP == domain 5 score: -0.5 bits; conditional E-value: 2.6 Sec8_N 62 ehhqaFnssiasYskilssiqesqe 86 F ++i+ Y+k+l+ ++e e FUN_000362-T1 755 YSRSEFRKAIKCYEKALNIFTEVGE 779 55678*************9998665 PP >> TPR_leprecan Leprecan family TPR-like repeat region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 8.3 4.8e+03 169 195 .. 459 485 .. 428 495 .. 0.63 2 ? -0.0 0.0 1.1 6.4e+02 144 195 .. 516 565 .. 499 569 .. 0.73 3 ? 5.9 0.0 0.017 10 170 199 .. 747 776 .. 735 784 .. 0.86 4 ? 1.9 0.0 0.29 1.7e+02 266 294 .. 787 815 .. 782 830 .. 0.73 5 ? -2.2 0.0 5 2.9e+03 265 287 .. 1117 1139 .. 1112 1151 .. 0.81 6 ? -2.5 0.0 6.4 3.7e+03 266 293 .. 1238 1265 .. 1236 1275 .. 0.76 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 8.3 TPR_leprecan 169 eefkagvrlyeeeearsaiedlekaLq 195 + f++g + ++ e+ ++ie +ek L+ FUN_000362-T1 459 AYFNLGFVYNSQSEFPKSIECFEKSLK 485 336667666666777777777777765 PP == domain 2 score: -0.0 bits; conditional E-value: 1.1 TPR_leprecan 144 dleyYkalagv.reeslkDleakphleefkagvrlyeeeearsaiedlekaLq 195 +e Y + ++ re+ +Dle ++l + g+ +y+++++ aie ek L+ FUN_000362-T1 516 AIECYEESLKIaREAGNRDLEGDAYL---NVGLFFYSQGDFPIAIECYEKSLK 565 55666554443266677888888776...468888888888888888888775 PP == domain 3 score: 5.9 bits; conditional E-value: 0.017 TPR_leprecan 170 efkagvrlyeeeearsaiedlekaLqeyfa 199 f++gv +y++ e+r+ai+ ekaL+ + + FUN_000362-T1 747 YFNLGVVYYSRSEFRKAIKCYEKALNIFTE 776 5999*********************87655 PP == domain 4 score: 1.9 bits; conditional E-value: 0.29 TPR_leprecan 266 ydyLqfayykvgdlkkaiecaksyllFdp 294 y +L ay +d+ kaiec + l+ FUN_000362-T1 787 YLKLGNAYKSHNDFPKAIECYEKSLIIAR 815 778899**************876666544 PP == domain 5 score: -2.2 bits; conditional E-value: 5 TPR_leprecan 265 hydyLqfayykvgdlkkaiecak 287 y +L y + d++kaiec + FUN_000362-T1 1117 AYFHLGAVYLSLSDFRKAIECHE 1139 57778888999999999999965 PP == domain 6 score: -2.5 bits; conditional E-value: 6.4 TPR_leprecan 266 ydyLqfayykvgdlkkaiecaksyllFd 293 y L y d+++aiec + ll FUN_000362-T1 1238 YLNLGLVYDSQSDFRNAIECYEKSLLIA 1265 5556677888999999999988877765 PP >> TPR_21 Tetratricopeptide repeat-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 2.9 1.7e+03 153 176 .. 64 87 .. 39 120 .. 0.71 2 ? 6.8 0.0 0.012 6.9 103 173 .. 487 564 .. 468 578 .. 0.80 3 ? 0.8 0.0 0.87 5.1e+02 128 171 .. 766 809 .. 750 817 .. 0.61 4 ? 1.3 0.0 0.6 3.5e+02 131 176 .. 889 934 .. 883 945 .. 0.77 5 ? -1.6 0.0 4.7 2.8e+03 151 178 .. 1160 1187 .. 1122 1194 .. 0.75 6 ? 0.8 0.1 0.82 4.8e+02 88 175 .. 1287 1377 .. 1264 1386 .. 0.76 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 2.9 TPR_21 153 GDilvaqgkldeAraAYqaAlaal 176 G ++ +q ++ +A + Y+++l+ FUN_000362-T1 64 GRVYDSQSDFPKAIECYEESLKIA 87 445555666666666666665544 PP == domain 2 score: 6.8 bits; conditional E-value: 0.012 TPR_21 103 adkakdeelkavarlrLarvllaekkydeALktLeakkdeafaalvaelkGDilva.......qgkldeAraAYqaAl 173 a++++d +++ a l L rv + + ++ +A++ e++ + a +a +l+GD++++ qg++ A + Y+++l FUN_000362-T1 487 ASEGRDRATEGDAYLNLGRVYFSQSDFCKAIECYEESLKIAREAGNRDLEGDAYLNvglffysQGDFPIAIECYEKSL 564 566778999999****************************************99752222222666666666666666 PP == domain 3 score: 0.8 bits; conditional E-value: 0.87 TPR_21 128 kydeALktLeakkdeafaalvaelkGDilvaqgkldeAraAYqa 171 y++AL+ +++ ++a ++ G ++ + +++ +A + Y++ FUN_000362-T1 766 CYEKALNIFTEVGEQALEGDSYLKLGNAYKSHNDFPKAIECYEK 809 45556666666666666665555556666666666666666665 PP == domain 4 score: 1.3 bits; conditional E-value: 0.6 TPR_21 131 eALktLeakkdeafaalvaelkGDilvaqgkldeAraAYqaAlaal 176 + L+ ++ d a +++++ G +++ g++ +A + Y+++l+ FUN_000362-T1 889 KSLNIAREAGDRATEGKANYNLGSVYLCRGDRSKAIECYEKSLHIA 934 5555556666667777777778*******************99755 PP == domain 5 score: -1.6 bits; conditional E-value: 4.7 TPR_21 151 lkGDilvaqgkldeAraAYqaAlaalee 178 G ++ q ++ +A + Y+++l+ e FUN_000362-T1 1160 HLGTVYHFQSDFPKAIECYEKSLDIARE 1187 56899999************99986655 PP == domain 6 score: 0.8 bits; conditional E-value: 0.82 TPR_21 88 ekgdlaaAkaqLewva...dkakdeelkavarlrLarvllaekkydeALktLeakkdeafaalvaelkGDilvaqgkldeAraAYqaAlaa 175 +++dl +A + +e+ + +a d +++ a l L + + ++ +A++ e++ + a++a + +G ++ + g + ++ + +A++ FUN_000362-T1 1287 SRNDLPKAMEFYEKSLnisREAGDRATEGKACLNLGLIYDSQSNFSKAIECYEKSLNIAWEAGDQATEGKAYFSLGIVYKLHKDFAKAFEC 1377 5666777766666544111455667777778888888999999999999999999999999999999999998888888888888888765 PP >> Foie-gras_1 Foie gras liver health family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 6.5 3.8e+03 170 214 .. 477 521 .. 472 530 .. 0.84 2 ? 5.0 0.0 0.039 22 167 222 .. 761 816 .. 737 818 .. 0.90 3 ? -1.4 0.0 3.7 2.1e+03 146 213 .. 860 927 .. 841 931 .. 0.76 4 ? 0.1 0.0 1.3 7.5e+02 169 226 .. 1174 1231 .. 1168 1257 .. 0.88 5 ? -0.6 0.0 2 1.2e+03 166 217 .. 1251 1302 .. 1232 1309 .. 0.85 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 6.5 Foie-gras_1 170 idlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellr 214 i++++++l+ +s+ + ++ l++++ y+ d+ ka+e ++ FUN_000362-T1 477 IECFEKSLKTASEGRDRATEGDAYLNLGRVYFSQSDFCKAIECYE 521 8999999999997666667777888***************99887 PP == domain 2 score: 5.0 bits; conditional E-value: 0.039 Foie-gras_1 167 kliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplalsyrq 222 +i+++++al F++ + + l+ l+++++y +d+ ka+e ++ ++ r+ FUN_000362-T1 761 RKAIKCYEKALNIFTEVGEQALEGDSYLKLGNAYKSHNDFPKAIECYEKSLIIARR 816 5689*****************************************99877666655 PP == domain 3 score: -1.4 bits; conditional E-value: 3.7 Foie-gras_1 146 apepheetelegseekgvdhskliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalell 213 + ++ +++ g+ + + d+s + ++++++l +++ + + ++ + ++++ yl gd +ka+e + FUN_000362-T1 860 KAKEGNAYLNLGNAYMSHDESPKAFNCYEKSLNIAREAGDRATEGKANYNLGSVYLCRGDRSKAIECY 927 55556666667777778888888888999998888888888888888889998888888888888876 PP == domain 4 score: 0.1 bits; conditional E-value: 1.3 Foie-gras_1 169 iidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrplalsyrqegWw 226 +i++++++l +++ + + ++ + ++++ y +d+ ka+e+++ ++ r+eg w FUN_000362-T1 1174 AIECYEKSLDIAREAGDRATEGSGYFNLGTVYKSRNDLPKAIEFYEKSLNIAREEGDW 1231 68999999999999998999999999********************998888888744 PP == domain 5 score: -0.6 bits; conditional E-value: 2 Foie-gras_1 166 skliidlLkraleeFskrkqtRlaeelsleiAeEylrlgdwakalellrpla 217 ++i++++++l ++k + + + + ++++ y +d+ ka+e+++ FUN_000362-T1 1251 FRNAIECYEKSLLIATKAGDRAAEGSGYFNLGTVYKSRNDLPKAMEFYEKSL 1302 5689************9998888899999******************98764 PP >> DUF627 Protein of unknown function (DUF627) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.35 2e+02 59 107 .. 33 87 .. 21 89 .. 0.85 2 ? -2.1 0.0 8.7 5e+03 62 106 .. 236 286 .. 232 288 .. 0.68 3 ? 4.5 0.0 0.078 45 62 107 .. 316 367 .. 312 368 .. 0.92 4 ? -0.9 0.0 3.7 2.1e+03 5 27 .. 507 529 .. 503 538 .. 0.81 5 ? -0.1 0.0 2.1 1.2e+03 62 107 .. 556 607 .. 554 608 .. 0.88 6 ? 0.4 0.1 1.5 8.8e+02 60 106 .. 761 813 .. 754 815 .. 0.86 7 ? -0.8 0.0 3.4 2e+03 5 27 .. 914 936 .. 912 957 .. 0.85 8 ? 0.5 0.0 1.4 8.2e+02 59 106 .. 1251 1304 .. 1244 1308 .. 0.82 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.35 DUF627 59 Llgsvecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsve 107 + s+ec++++ ++ + ++l++ ++s++++ ka++ +++L++ FUN_000362-T1 33 FSKSIECYEKSLKIAseggdrATEGDAYLNLGRVYDSQSDFPKAIECYEESLKIA 87 56799999999999999999888888999****************9999999875 PP == domain 2 score: -2.1 bits; conditional E-value: 8.7 DUF627 62 svecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsv 106 s+ec++++ ++ ++l+ ++s++++ ka++ +++L++ FUN_000362-T1 236 SIECYEKSLTIAkeagdrVTEGDAYLNLGLVYDSQSDFPKAIECYEKSLKI 286 677777777776666665444555667777778888888888777777765 PP == domain 3 score: 4.5 bits; conditional E-value: 0.078 DUF627 62 svecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsve 107 s+ec++++ ++ + +f+l+ ++s++++ kav+ +++L++ FUN_000362-T1 316 SIECYEKSLRIAseggdrATEGDAFFNLGLVYDSQSDFPKAVECYEKSLKIA 367 99*******99999999999999********************999999875 PP == domain 4 score: -0.9 bits; conditional E-value: 3.7 DUF627 5 lfargnhikALeiiedlisrhke 27 +f + + +kA+e e++++ +e FUN_000362-T1 507 YFSQSDFCKAIECYEESLKIARE 529 78999999999999999877766 PP == domain 5 score: -0.1 bits; conditional E-value: 2.1 DUF627 62 svecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsve 107 ++ec++++ ++ + + ++l++ + s+++++k + ++ +Ls+ FUN_000362-T1 556 AIECYEKSLKIAsegvdwATEGKVYLNLGHVYYSQSDFRKETECCENSLSIA 607 788999998888888888888889999*********************9986 PP == domain 6 score: 0.4 bits; conditional E-value: 1.5 DUF627 60 lgsvecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsv 106 + +++c+++a ++ ++ s ++l++ ++s ++ ka++ +++L + FUN_000362-T1 761 RKAIKCYEKALNIFtevgeqALEGDSYLKLGNAYKSHNDFPKAIECYEKSLII 813 6689999999998889999899999999*********9999999988888765 PP == domain 7 score: -0.8 bits; conditional E-value: 3.4 DUF627 5 lfargnhikALeiiedlisrhke 27 ++ rg++ kA+e e+++ +e FUN_000362-T1 914 YLCRGDRSKAIECYEKSLHIAGE 936 5679*********9999877766 PP == domain 8 score: 0.5 bits; conditional E-value: 1.4 DUF627 59 Llgsvecfseavels......rfcArsLfelasqlgsvlyYkkavkkakqaLsv 106 +++++ec++++ + + + f+l+ ++s+ + ka++ +++L + FUN_000362-T1 1251 FRNAIECYEKSLLIAtkagdrAAEGSGYFNLGTVYKSRNDLPKAMEFYEKSLNI 1304 689******999999899877777788899999999998888888877777765 PP >> DUF1187 Protein of unknown function (DUF1187) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 5 2.9e+03 22 42 .. 232 252 .. 228 257 .. 0.75 2 ? -0.1 0.0 3.1 1.8e+03 21 42 .. 351 372 .. 347 380 .. 0.81 3 ? 6.2 0.1 0.032 18 21 42 .. 591 612 .. 584 622 .. 0.75 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 5 DUF1187 22 dskltkeeCeknlskkkeAGk 42 +++ e ek l keAG FUN_000362-T1 232 NFPKSIECYEKSLTIAKEAGD 252 555555555999*******95 PP == domain 2 score: -0.1 bits; conditional E-value: 3.1 DUF1187 21 sdskltkeeCeknlskkkeAGk 42 sd++ e ek l keAG FUN_000362-T1 351 SDFPKAVECYEKSLKIAKEAGD 372 77776666669*********95 PP == domain 3 score: 6.2 bits; conditional E-value: 0.032 DUF1187 21 sdskltkeeCeknlskkkeAGk 42 sd++ e Ce ls keAG FUN_000362-T1 591 SDFRKETECCENSLSIAKEAGD 612 4555556679**********96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1411 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 407 (0.0159327); expected 510.9 (0.02) Passed bias filter: 366 (0.0143277); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 45 (0.0017616); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 44 [number of targets reported over threshold] # CPU time: 0.67u 0.50s 00:00:01.17 Elapsed: 00:00:00.56 # Mc/sec: 10151.09 // Query: FUN_000365-T1 [L=106] Description: FUN_000365 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.26 10.9 0.9 0.3 10.7 0.9 1.0 1 Hanta_Gn-H Hantavirus glycoprotein Gn, head Domain annotation for each model (and alignments): >> Hanta_Gn-H Hantavirus glycoprotein Gn, head # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.9 1.2e-05 0.3 43 117 .. 18 92 .. 3 96 .. 0.87 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 1.2e-05 Hanta_Gn-H 43 qslntitkytqvswrgkadqsqssqnsfetvstevdlkgtcvlkhkmveesyrsrksvtcydlscnstyckptly 117 s i + + +s+ d+ s++s vs + ++ + k+k + r+ d+ c s yck l FUN_000365-T1 18 VSRRDIQRASFLSYSPDNDKETDSNESDTGVSEQSEVCSSRKKKRKGRRRVWEERRVNDLVDVICSSEYCKKKLV 92 466678888889999999*******************999999****************************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (106 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1024 (0.0400861); expected 510.9 (0.02) Passed bias filter: 391 (0.0153063); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.43 # Mc/sec: 996.74 // Query: FUN_000366-T1 [L=346] Description: FUN_000366 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-08 34.0 0.3 6.4e-08 33.2 0.3 1.4 1 TPR_12 Tetratricopeptide repeat 1e-05 25.6 0.9 0.00016 21.8 0.1 2.4 2 TPR_1 Tetratricopeptide repeat 0.00015 22.1 0.8 0.0017 18.8 0.1 2.4 2 TPR_2 Tetratricopeptide repeat 0.0013 19.2 0.6 0.012 16.2 0.1 2.6 3 TPR_8 Tetratricopeptide repeat 0.0019 18.6 0.0 0.0045 17.5 0.0 1.5 1 TPR_7 Tetratricopeptide repeat 0.0066 16.9 0.0 0.017 15.6 0.0 1.7 1 TPR_10 Tetratricopeptide repeat ------ inclusion threshold ------ 0.21 11.7 0.1 0.33 11.1 0.1 1.3 1 RPN7 26S proteasome subunit RPN7 Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.2 0.3 1.8e-11 6.4e-08 22 77 .] 257 310 .. 243 310 .. 0.94 Alignments for each domain: == domain 1 score: 33.2 bits; conditional E-value: 1.8e-11 TPR_12 22 AlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++e+le ++e a+++ +d+ + a + Lg++y+ +gd+++A+e+++++l++aek FUN_000366-T1 257 SQEYLESSIEFARQA--DDRATERKANFYLGIVYSSRGDHRQAIEFYKKSLDMAEK 310 789************..************************************996 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.1 4.4e-08 0.00016 5 31 .. 282 308 .. 279 310 .. 0.89 2 ? 1.8 0.1 0.096 3.5e+02 6 16 .. 323 333 .. 319 333 .. 0.86 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 4.4e-08 TPR_1 5 ynlGnayfklgkydeAleyyekALeln 31 + lG +y + g++ +A+e+y+k L FUN_000366-T1 282 FYLGIVYSSRGDHRQAIEFYKKSLDMA 308 78*********************9865 PP == domain 2 score: 1.8 bits; conditional E-value: 0.096 TPR_1 6 nlGnayfklgk 16 lGn yf lgk FUN_000366-T1 323 YLGNSYFVLGK 333 69******997 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.1 4.8e-07 0.0017 2 32 .. 279 309 .. 278 311 .. 0.91 2 ? 1.2 0.1 0.21 7.7e+02 5 16 .. 322 333 .. 319 334 .. 0.84 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 4.8e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +a ++lG +y +gd+ +A+e+y+k+l ++ FUN_000366-T1 279 KANFYLGIVYSSRGDHRQAIEFYKKSLDMAE 309 5789***********************8775 PP == domain 2 score: 1.2 bits; conditional E-value: 0.21 TPR_2 5 ynlGlayyklgd 16 +lG++y+ lg+ FUN_000366-T1 322 QYLGNSYFVLGK 333 69******9996 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.63 2.3e+03 13 27 .. 257 271 .. 253 276 .. 0.73 2 ! 16.2 0.1 3.4e-06 0.012 7 32 .. 284 309 .. 279 310 .. 0.89 3 ? -3.9 0.0 7 2.6e+04 3 10 .. 327 334 .. 326 335 .. 0.80 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.63 TPR_8 13 klgdyeeAkeyyeka 27 +++++e ++e+ ++a FUN_000366-T1 257 SQEYLESSIEFARQA 271 566778888888887 PP == domain 2 score: 16.2 bits; conditional E-value: 3.4e-06 TPR_8 7 lGliylklgdyeeAkeyyekaleldp 32 lG +y++ gd+ +A+e+y+k+l++++ FUN_000366-T1 284 LGIVYSSRGDHRQAIEFYKKSLDMAE 309 8999******************9987 PP == domain 3 score: -3.9 bits; conditional E-value: 7 TPR_8 3 ayynlGli 10 +y+ lG++ FUN_000366-T1 327 SYFVLGKA 334 79999987 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 1.2e-06 0.0045 5 31 .. 284 310 .. 284 313 .. 0.91 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1.2e-06 TPR_7 5 LariyrklGdydeAirlyerlLalakd 31 L+ +y+++Gd ++Ai++y++ L++a++ FUN_000366-T1 284 LGIVYSSRGDHRQAIEFYKKSLDMAEK 310 899*****************9988875 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 4.6e-06 0.017 8 35 .. 284 311 .. 283 311 .. 0.95 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 4.6e-06 TPR_10 8 LanalraqgryeeAeelleealairerv 35 L+ +++++g++ A e+++++l+++e++ FUN_000366-T1 284 LGIVYSSRGDHRQAIEFYKKSLDMAEKA 311 9************************985 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 9.1e-05 0.33 15 70 .. 257 312 .. 250 318 .. 0.88 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 9.1e-05 RPN7 15 eleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslg 70 e Le+ ++ a++ r+a+ l+ y + gd+++A+++y++ ++ + +g FUN_000366-T1 257 SQEYLESSIEFARQADDRATERKANFYLGIVYSSRGDHRQAIEFYKKSLDMAEKAG 312 567899999*99999999999**************************999877666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (346 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 431 (0.0168722); expected 510.9 (0.02) Passed bias filter: 419 (0.0164024); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 3300.57 // Query: FUN_000367-T1 [L=126] Description: FUN_000367 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0049 17.5 0.6 0.0088 16.7 0.3 1.6 2 Rsbr_N Rsbr N terminal Domain annotation for each model (and alignments): >> Rsbr_N Rsbr N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 0.08 2.1e+03 27 61 .. 43 74 .. 24 79 .. 0.53 2 ! 16.7 0.3 3.4e-07 0.0088 25 73 .. 78 126 .] 59 126 .] 0.86 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.08 Rsbr_N 27 kisdelyeetskefvdlilssvkeneeeaeeelee 61 + ++ ++++ +++ l++++ +++++ +le+ FUN_000367-T1 43 SKKERVWTNAEMKYL--ALEQAE-EKKQFVVRLET 74 445566655555543..455555.55555555555 PP == domain 2 score: 16.7 bits; conditional E-value: 3.4e-07 Rsbr_N 25 lqkisdelyeetskefvdlilssvkeneeeaeeeleefserlvqlGwpL 73 ++ +++++ee+sk+f +l+ls+ ++e+e+ + l+ +s + vq pL FUN_000367-T1 78 KKSSNNQVFEEISKDFEKLLLSDEFKEENECASLLDLLSRKSVQKTRPL 126 455679****************9999******************98776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1749 (0.0684674); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.68s 00:00:01.01 Elapsed: 00:00:00.52 # Mc/sec: 980.24 // Query: FUN_000368-T1 [L=185] Description: FUN_000368 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 753 (0.0294774); expected 510.9 (0.02) Passed bias filter: 648 (0.025367); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 1889.29 // Query: FUN_000369-T1 [L=490] Description: FUN_000369 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-10 40.6 0.1 9.4e-10 39.3 0.1 1.6 1 Ig_3 Immunoglobulin domain 2.7e-09 37.6 0.1 5.3e-09 36.7 0.1 1.4 1 Ig_2 Immunoglobulin domain 6.7e-08 33.0 1.1 1.7e-07 31.7 0.3 2.1 2 I-set Immunoglobulin I-set domain 9e-05 23.2 0.2 0.00027 21.7 0.2 1.8 1 ig Immunoglobulin domain 0.00026 21.8 1.4 0.0007 20.4 1.4 1.6 1 Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 e 0.00046 20.8 1.3 0.75 10.5 0.1 2.5 2 V-set Immunoglobulin V-set domain 0.0076 17.3 0.5 0.022 15.8 0.5 1.8 1 Ig_4 T-cell surface glycoprotein CD3 delta chain ------ inclusion threshold ------ 0.029 14.7 0.1 0.081 13.3 0.1 1.8 1 Ig_6 Immunoglobulin domain Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.1 2.9e-13 9.4e-10 3 76 .. 308 371 .. 308 372 .. 0.88 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 2.9e-13 Ig_3 3 vitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvA 76 +i v+p+s++ +eg++v+L+Cea+gn +++W+k+g+ + +++ + L +++v+ d G+Y C++ FUN_000369-T1 308 KIAVQPQSQTKKEGSRVELRCEATGNEL-SYSWLKDGQ---E---M---EGQRGCCLVFEQVSMADFGSYVCQV 371 5889*******************77665.8********...5...2...356899*****************98 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.7 0.1 1.7e-12 5.3e-09 5 79 .] 312 387 .. 307 387 .. 0.88 Alignments for each domain: == domain 1 score: 36.7 bits; conditional E-value: 1.7e-12 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn..fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++++++ eg+ v L+C+a gn + +y+w kdg++++ ++ ++ +vs d G Y C+++ ++++++s e+ v FUN_000369-T1 312 QPQSQTKKEGSRVELRCEATGN-ELSYSWLKDGQEMEGQRGccLVFEQVSMADFGSYVCQVKKKDQSCSSEVAELDV 387 45557789*************9.9*************777775555************************9999876 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 4.4 1.4e+04 54 73 .. 147 166 .. 134 171 .. 0.74 2 ! 31.7 0.3 5.2e-11 1.7e-07 2 86 .. 308 382 .. 307 387 .. 0.87 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 4.4 I-set 54 gtatLtIsnvkkeDeGkYtc 73 ++++L+++ v ++ +GkY + FUN_000369-T1 147 DSKKLKLKFVYQRGTGKYIL 166 46788889999999999976 PP == domain 2 score: 31.7 bits; conditional E-value: 5.2e-11 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasa 86 k+ ++++++ keG+++el c+++G+ e++ sWlkdg+e++ +++ + L++++v+++D G+Y c+++ + +++++++ FUN_000369-T1 308 KIAVQPQSQTKKEGSRVELRCEATGN-ELSYSWLKDGQEMEG-------QRG--CCLVFEQVSMADFGSYVCQVKKKDQSCSSEV 382 577899********************.78************6.......445..8999999**************9977776654 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.2 8.5e-08 0.00027 2 75 .. 315 376 .. 314 382 .. 0.91 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 8.5e-08 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpgg 75 + t +eG++++L+C+a+ +++W k+g++++ ++ + l + +v++ d G Y C+v + FUN_000369-T1 315 SQTKKEGSRVELRCEAT--GNELSYSWLKDGQEMEGQR----------GCCLVFEQVSMADFGSYVCQVKKKDQ 376 67889************..*****************95..........5********************98765 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 1.4 2.2e-07 0.0007 5 62 .. 319 376 .. 316 390 .. 0.85 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 2.2e-07 Ig_5 5 isgttVtltCpeese.eeikWekndkelkdkeekeLvlenFsevedsGyysCykesskk 62 g++V+l+C + + + +W k+++e++++++ Lv e+ s + d G+y+C+ +++++ FUN_000369-T1 319 KEGSRVELRCEATGNeLSYSWLKDGQEMEGQRGCCLVFEQVS-MADFGSYVCQVKKKDQ 376 5799******9776537899*******************976.799******9998654 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.2 0.00034 1.1 2 43 .. 312 350 .. 311 358 .. 0.78 2 ! 10.5 0.1 0.00024 0.75 75 108 .. 354 387 .. 347 388 .. 0.83 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00034 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrqppgk.ept 43 +p++ t+ eG +v+L+C+ + ++ s++W ++ ++ +++ FUN_000369-T1 312 QPQSQTKKEGSRVELRCEATG----NELSYSWLKDGQEMeGQR 350 79999************8886....59******9887655444 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00024 V-set 75 ltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 l +++++++D G+Y C+v +k+++ +++ +L V FUN_000369-T1 354 LVFEQVSMADFGSYVCQVKKKDQSCSSEVAELDV 387 7789*************98888877877777766 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.5 6.9e-06 0.022 3 55 .. 323 377 .. 321 385 .. 0.82 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 6.9e-06 Ig_4 3 kVlLtCnsss..keitwlkdgkeikeskektldlgksiedprglYqCkeeekkks 55 +V L+C+ + ++ wlkdg+e++ ++ l ++++ + g Y+C+ ++k++s FUN_000369-T1 323 RVELRCEATGneLSYSWLKDGQEMEGQRGCCLVFEQVSMADFGSYVCQVKKKDQS 377 799***766523579**************9******************6566655 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 2.5e-05 0.081 69 103 .. 348 379 .. 309 397 .. 0.81 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.5e-05 Ig_6 69 ileknaLrfkpvkvndsGlYiCrprirspqekacc 103 + + L f+ v + d G+Y+C++ ++++++c FUN_000369-T1 348 GQRGCCLVFEQVSMADFGSYVCQV---KKKDQSCS 379 478899****************93...44666664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (490 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 669 (0.0261891); expected 510.9 (0.02) Passed bias filter: 560 (0.0219221); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4698.51 // Query: FUN_000370-T1 [L=206] Description: FUN_000370 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-52 176.9 0.3 4.2e-52 176.5 0.3 1.1 1 Ras Ras family 1.2e-21 77.7 0.4 2.2e-21 76.8 0.1 1.6 2 Roc Ras of Complex, Roc, domain of DAPkinase 5.9e-11 42.6 0.3 8.2e-11 42.2 0.3 1.2 1 Arf ADP-ribosylation factor family 2.3e-05 24.5 0.1 3.3e-05 24.1 0.1 1.2 1 GTP_EFTU Elongation factor Tu GTP binding domain ------ inclusion threshold ------ 0.022 14.7 0.1 0.031 14.2 0.1 1.3 1 Gtr1_RagA Gtr1/RagA G protein conserved region 0.19 12.5 0.2 0.43 11.3 0.1 1.7 1 Tor_FN3_2nd Tyrosine-protein kinase receptor torso, second F 0.23 12.1 1.5 0.31 11.6 0.1 2.0 2 DUF6974 Domain of unknown function (DUF6974) Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.5 0.3 1.1e-55 4.2e-52 32 161 .. 42 171 .. 38 172 .. 0.98 Alignments for each domain: == domain 1 score: 176.5 bits; conditional E-value: 1.1e-55 Ras 32 igvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwleeikrvaeenvpivlvGnkvDleekrevsteeg 127 +g+dfk++t+e+dgk++klqiwDTAGqerfr++++ayyrga+gi+lvydit+ +sfen+k+w+++i+++a+++v+ +++Gnk+D+e++r+v++++g FUN_000370-T1 42 LGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKSFENIKNWIRNIEEHASSDVEKMVLGNKCDMEDRRAVTKDRG 137 599********************************************************************************************* PP Ras 128 eelakelglkfletSAktkenveeafeelvreil 161 +la e+g+kf+etSAk++ nveeaf +l+r+i+ FUN_000370-T1 138 TQLATEYGIKFMETSAKSSINVEEAFFTLARDIK 171 *******************************986 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.8 0.1 6.1e-25 2.2e-21 33 119 .] 43 125 .. 40 125 .. 0.85 2 ? -3.5 0.0 4.7 1.7e+04 27 42 .. 139 154 .. 130 163 .. 0.57 Alignments for each domain: == domain 1 score: 76.8 bits; conditional E-value: 6.1e-25 Roc 33 gvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srssenlkeWlkelkevagks.pvilvgnkiD 119 g+df+ +++ ++ + kkikl+iWDtaGqerfr++++ yyr+a +++lv+d ++s+en+k+W+++++e+a+++ +++gnk+D FUN_000370-T1 43 GIDFKIRTI-EL-------DGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDitnDKSFENIKNWIRNIEEHASSDvEKMVLGNKCD 125 666655544.23.......3579*********************************87666889************99774789******9 PP == domain 2 score: -3.5 bits; conditional E-value: 4.7 Roc 27 kekstigvdflskelt 42 + + +g++f++ +++ FUN_000370-T1 139 QLATEYGIKFMETSAK 154 4455566777665543 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.2 0.3 2.2e-14 8.2e-11 47 166 .. 45 162 .. 40 170 .. 0.78 Alignments for each domain: == domain 1 score: 42.2 bits; conditional E-value: 2.2e-14 Arf 47 gfnveevei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLkalleeeelkeaallvlaNKqDlpealseaeikeal 140 f+++++e k++k+++wD Gqe+ R + Y++ +++ v D ++ + +e+ k+ ++++ ee+ +++ +vl+NK D+++ +++ FUN_000370-T1 45 DFKIRTIELdgKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKSFENIKNWIRNI-EEHASSDVEKMVLGNKCDMEDRR---AVTKDR 136 6777777765599*********************************************99996.778899*************9753...344444 PP Arf 141 gleelkkrkleiqkcsavkgeglkeg 166 g + ++ ++ +++sa + +++e+ FUN_000370-T1 137 GTQLATEYGIKFMETSAKSSINVEEA 162 44444455555555555555555555 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.1 8.9e-09 3.3e-05 54 177 .. 43 161 .. 42 181 .. 0.77 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 8.9e-09 GTP_EFTU 54 GiTiksaavsfetkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveG....vepqteevlrlarklgvpiivviNKmDrvdeaelkevvee 145 Gi k+ ++++++kk ++++ Dt G + F +++ ++ + g +lv d++++ ++ ++++ + +v+ +v+ NK+D+ + + v ++ FUN_000370-T1 43 GIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDksfeNIKNWIRNIEEHASSDVEKMVLGNKCDME---DRRAVTKD 135 67789999******************************************9944432333444555666678889*********9...44455555 PP GTP_EFTU 146 vkeellekvgekgekevpvvpgSalkgegvke 177 ++l +++ ++++ +Sa++ +v+e FUN_000370-T1 136 RGTQLATEY------GIKFMETSAKSSINVEE 161 555563333......35678888888888775 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 8.6e-06 0.031 36 132 .. 45 132 .. 30 167 .. 0.70 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 8.6e-06 Gtr1_RagA 36 dveksevrfl.gnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedlarlketlealsev.speakvfvlihKvDlisedkr 129 d + ++++ ++++l++wd Gqe+f + + ++ ++ v D++ +++++++k+ ++++ e+ s +++ vl +K+D ++ FUN_000370-T1 45 DFKIRTIELDgKKIKLQIWDTAGQERFRTIT-----TAYYRGAMGIMLVYDIT---NDKSFENIKNWIRNIEEHaSSDVEKMVLGNKCDMEDR--- 129 44444444441579***********998876.....55677777888999**9...78899999999999987537899999******97542... PP Gtr1_RagA 130 eev 132 + v FUN_000370-T1 130 RAV 132 222 PP >> Tor_FN3_2nd Tyrosine-protein kinase receptor torso, second FN3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 0.00012 0.43 31 71 .. 87 127 .. 65 138 .. 0.84 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00012 Tor_FN3_2nd 31 lcfdianicqntnmkhakiwptahpsfdvenlvlndeceih 71 l++di+n n+k h s dve++vl ++c++ FUN_000370-T1 87 LVYDITNDKSFENIKNWIRNIEEHASSDVEKMVLGNKCDME 127 78999999999999988888899***************985 PP >> DUF6974 Domain of unknown function (DUF6974) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.1 4.8 1.8e+04 34 48 .. 13 27 .. 3 29 .. 0.66 2 ? 11.6 0.1 8.6e-05 0.31 50 95 .. 80 124 .. 56 128 .. 0.83 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 4.8 DUF6974 34 kkaGlLrftvsriWN 48 + +L+++ + +WN FUN_000370-T1 13 EAWKVLKWKPQLLWN 27 444567787777887 PP == domain 2 score: 11.6 bits; conditional E-value: 8.6e-05 DUF6974 50 egvfrlglvfeYkdekafkdcqklieeaeeltekeevtlkvisnRg 95 g+ ++lv++ ++k+f++ ++ i+++e +++++v v +n++ FUN_000370-T1 80 RGAMGIMLVYDITNDKSFENIKNWIRNIE-EHASSDVEKMVLGNKC 124 5777899*********************9.5667777777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (206 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1244 (0.0486984); expected 510.9 (0.02) Passed bias filter: 870 (0.0340575); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.34u 0.50s 00:00:00.84 Elapsed: 00:00:00.69 # Mc/sec: 1204.99 // Query: FUN_000371-T1 [L=183] Description: FUN_000371 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-61 206.8 0.1 2.3e-61 206.6 0.1 1.0 1 Ras Ras family 1.8e-35 122.2 0.1 2.5e-35 121.8 0.1 1.2 1 Roc Ras of Complex, Roc, domain of DAPkinase 8.3e-20 71.5 0.0 1e-19 71.2 0.0 1.0 1 Arf ADP-ribosylation factor family 1.9e-07 31.3 0.1 2.5e-06 27.7 0.1 2.1 1 GTP_EFTU Elongation factor Tu GTP binding domain 2e-05 24.6 0.0 2.4e-05 24.4 0.0 1.2 1 Gtr1_RagA Gtr1/RagA G protein conserved region 7.9e-05 23.2 0.0 0.00012 22.6 0.0 1.3 1 MMR_HSR1 50S ribosome-binding GTPase 0.00011 22.6 0.0 0.0027 18.0 0.0 2.0 2 ATP_bind_1 Conserved hypothetical ATP binding protein 0.00064 19.6 0.0 0.00084 19.2 0.0 1.2 1 SRPRB Signal recognition particle receptor beta subuni 0.0013 19.0 0.0 1.4 9.2 0.0 2.3 2 RsgA_GTPase RsgA GTPase 0.0047 17.3 0.0 0.0063 16.9 0.0 1.3 1 NTPase_1 NTPase ------ inclusion threshold ------ 0.014 15.6 0.0 0.059 13.7 0.0 2.1 1 PduV-EutP Ethanolamine utilisation - propanediol utilisati 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 AAA_7 P-loop containing dynein motor region 0.043 14.6 0.0 0.088 13.6 0.0 1.6 1 AAA_22 AAA domain 0.046 13.9 0.0 0.079 13.1 0.0 1.7 1 AAA_24 AAA domain 0.052 14.6 0.0 0.076 14.0 0.0 1.5 1 AAA_16 AAA ATPase domain 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 Septin Septin 0.14 12.9 0.0 0.19 12.5 0.0 1.4 1 RXYLT1_N RXYLT1 N-terminal domain Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 206.6 0.1 1.5e-64 2.3e-61 1 161 [. 11 171 .. 11 172 .. 0.99 Alignments for each domain: == domain 1 score: 206.6 bits; conditional E-value: 1.5e-64 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwlee 96 k++++GdsgvGK++l++rf+++ F+++y+sTig+d ++tv++dgk+v+lqiwDTAGqerfr+l++ay+rga+gi+lvydit e+sf+n+++wl++ FUN_000371-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTIGIDCRSRTVDLDGKRVRLQIWDTAGQERFRTLTSAYFRGAMGIVLVYDITTEDSFKNITQWLQN 106 89********************************************************************************************** PP Ras 97 ikrvaeenvpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 i++ a++nv +lvGnk D+e++re+ + +g +++++ +++f+etSA+t e+v+eaf++++r+i+ FUN_000371-T1 107 IDENASRNVCKILVGNKLDCEDEREIAKFRGLSMSENAEFEFFETSARTGEGVSEAFMAVARQIK 171 ***************************************************************97 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 121.8 0.1 1.7e-38 2.5e-35 1 119 [] 11 125 .. 11 125 .. 0.91 Alignments for each domain: == domain 1 score: 121.8 bits; conditional E-value: 1.7e-38 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srsse 93 K+++lGdsgvGKt+l+ rf+ed f++++ stig+d s+++ +++g k+++l+iWDtaGqerfr+l++ y+r+a +++lv+d ++s++ FUN_000371-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTIGIDCRSRTV-DLDG-------KRVRLQIWDTAGQERFRTLTSAYFRGAMGIVLVYDittEDSFK 98 9***********************************99986.4444.......789********************************86555789 PP Roc 94 nlkeWlkelkevagkspv.ilvgnkiD 119 n+ +Wl++++e+a+++++ ilvgnk+D FUN_000371-T1 99 NITQWLQNIDENASRNVCkILVGNKLD 125 ***********999875449*****98 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.2 0.0 6.8e-23 1e-19 14 173 .. 9 169 .. 3 170 .. 0.89 Alignments for each domain: == domain 1 score: 71.2 bits; conditional E-value: 6.8e-23 Arf 14 elrilllGLDnaGKtTilkklkleelvt.tiPTigfnveevei....knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeL 104 ++il+lG + GKt ++ ++ ++ +++ i Tig + ++ ++ k +++++wD Gqe+ R l + Yf+ +++ v D + ++ +++ + L FUN_000371-T1 9 TYKILILGDSGVGKTCLIFRFIEDIFSDsYISTIGIDCRSRTVdldgKRVRLQIWDTAGQERFRTLTSAYFRGAMGIVLVYDITTEDSFKNITQWL 104 68*******************99998764899*9987664333335599*********************************************** PP Arf 105 kalleeeelkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkeglewlses 173 +++ +e+ +++ ++++NK D ++ e+ei++ gl+ ++ ++e +++sa +geg++e++ ++++ FUN_000371-T1 105 QNI-DENASRNVCKILVGNKLDCED---EREIAKFRGLSMSENAEFEFFETSARTGEGVSEAFMAVARQ 169 *97.6777788888889*****885...78999999***99*********************9888766 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.1 1.6e-09 2.5e-06 54 186 .. 43 170 .. 7 172 .. 0.80 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 1.6e-09 GTP_EFTU 54 GiTiksaavsfetkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveGvepqteevlrlarklgvp....iivviNKmDrvdeaelkevvee 145 Gi s +v +++k+ ++++ Dt G + F +++ + + g vlv d+++ + + +++ +++ i+v NK+D de e+ + FUN_000371-T1 43 GIDCRSRTVDLDGKRVRLQIWDTAGQERFRTLTSAYFRGAMGIVLVYDITTEDSFKNITQWLQNIDENASrnvcKILVGNKLDCEDEREIAKFRGL 138 667778899999**************************************99555555555555544433333389999******66666555444 PP GTP_EFTU 146 vkeellekvgekgekevpvvpgSalkgegvkellealvell 186 e+ e++++ +Sa +gegv e + a+ + + FUN_000371-T1 139 SM-------SEN--AEFEFFETSARTGEGVSEAFMAVARQI 170 33.......233..3699************99888877665 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.0 1.6e-08 2.4e-05 1 127 [. 11 130 .. 11 170 .. 0.77 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 1.6e-08 Gtr1_RagA 1 kvLLmGksksGKsSirsviFsnyspkdtlrlgatidveksevrflg.nltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedl 95 k+L++G s+ GK+++ F + + d ++ id +v + g + l++wd Gqe+f + + + f+ ++ v D++ +e+++ FUN_000371-T1 11 KILILGDSGVGKTCLIFR-FIEDIFSDSYISTIGIDCRSRTVDLDGkRVRLQIWDTAGQERFRTLT-----SAYFRGAMGIVLVYDIT---TEDSF 97 89************7532.333445566666666777778887765269***********997765.....788**************...67777 PP Gtr1_RagA 96 arlketlealsevspeakvfvli.hKvDlised 127 +++++ l+++ e+ + +l+ +K+D +e+ FUN_000371-T1 98 KNITQWLQNIDENASRNVCKILVgNKLDCEDER 130 888888888888777666666665677766554 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 8.2e-08 0.00012 1 112 [. 11 122 .. 11 123 .. 0.74 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 8.2e-08 MMR_HSR1 1 rvaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkg..kkielvDtpGliegaseee.gleraflaieeadlillvvd..aeeglte 91 ++ i+G + vGK+ Li + +++ s + d ++++l+g +++++Dt+G e ++ l++a+ + a i+lv d +e+++++ FUN_000371-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTIGIDCRSRTVDLDGkrVRLQIWDTAG-QE----RFrTLTSAYFR--GAMGIVLVYDitTEDSFKN 99 589******************9777777777777888888887763366899*****.65....44477777774..58999****9886567888 PP MMR_HSR1 92 ldeeleellee..ekkpvilvln 112 +++ l+++ e+ ++ ilv n FUN_000371-T1 100 ITQWLQNIDENasRNVCKILVGN 122 88888888766333333455655 PP >> ATP_bind_1 Conserved hypothetical ATP binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.058 87 1 21 [. 14 34 .. 14 54 .. 0.77 2 ! 18.0 0.0 1.8e-06 0.0027 92 213 .. 59 176 .. 40 183 .] 0.80 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.058 ATP_bind_1 1 vvGpaGsGKttfvgalseile 21 ++G G+GKt ++ +++e + FUN_000371-T1 14 ILGDSGVGKTCLIFRFIEDIF 34 6899*********99887544 PP == domain 2 score: 18.0 bits; conditional E-value: 1.8e-06 ATP_bind_1 92 dyvlfDtPGQielftlseslakiveaLesefalvavvLvDtrrltdptkflsalllalsimlrlelPfvvalnkfDllke...lekelewfedvea 184 + + Dt GQ ++ tl ++ + ++a+++v + D ++ +d++k + + l+ + ++++ +++ nk+D +e ++++ +++ + FUN_000371-T1 59 RLQIWDTAGQERFRTLTSAYF--------RGAMGIVLVYDITT-EDSFKNITQWLQNIDENASRNVCKILVGNKLDCEDEreiAKFRGLSMSENAE 145 78899****************........***********876.6669999999999********************9978787777777777777 PP ATP_bind_1 185 lslllekee..skykklaeaiaelleefalv 213 ++ +++ + + +++ a+a+ ++ef++ FUN_000371-T1 146 FEFFETSARtgEGVSEAFMAVARQIKEFQDR 176 7777777777766777777777777777765 PP >> SRPRB Signal recognition particle receptor beta subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 5.6e-07 0.00084 5 114 .. 11 120 .. 8 148 .. 0.79 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 5.6e-07 SRPRB 5 tviiaGlsdsGKtslftkLttdsvrktvtSq..epsvalry....kgkkltliDfPGhdklrqklletlkdssslkglvfvvDStvdpkevtdvAE 94 +++i G s GKt l+ + +d ++++S + + + k +l++ D G++++r+ + + + + g+v v D t ++ +++ FUN_000371-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTigIDCRSRTVdldgKRVRLQIWDTAGQERFRTLTSAY---FRGAMGIVLVYDITTED-SFKNITQ 102 699***************************96656666666787788888999*********865555...6789999*999998765.5666777 PP SRPRB 95 flyevllitekkkdkidili 114 +l ++ + +++ +il+ FUN_000371-T1 103 WLQNIDENA--SRNVCKILV 120 777764333..355555555 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.2 0.0 0.00092 1.4 109 127 .. 12 30 .. 5 42 .. 0.82 2 ! 7.7 0.0 0.0026 4 51 102 .. 112 164 .. 83 174 .. 0.72 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00092 RsgA_GTPase 109 tvllGqSGvGKStLinall 127 +++lG SGvGK+ Li ++ FUN_000371-T1 12 ILILGDSGVGKTCLIFRFI 30 4679**********97665 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0026 RsgA_GTPase 51 esgiepvivlnKiDlleeee.eleelkkeyealgyevllvsaktgegleelke 102 ++++ ++v nK+D+ +e+e + + + e++++e++ +sa+tgeg+ e FUN_000371-T1 112 SRNVCKILVGNKLDCEDEREiAKFRGLSMSENAEFEFFETSARTGEGVSEAFM 164 4567788999**********43334457889999************9987655 PP >> NTPase_1 NTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 4.2e-06 0.0063 1 57 [. 11 70 .. 11 119 .. 0.74 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 4.2e-06 NTPase_1 1 kifiTGepGvGKtTlvekvaeklkek.gvkvgGfyteevr..eggkrigFkivdlasgee 57 ki+i G +GvGKt l+ + +e + ++ +++ G+ ++ + +gkr++ +i d a +e+ FUN_000371-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDsYISTIGIDCRSRTvdLDGKRVRLQIWDTAGQER 70 68999***********9999887665267899**9986554489**********966555 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 3.9e-05 0.059 3 56 .. 11 66 .. 9 167 .. 0.62 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.9e-05 PduV-EutP 3 killiGkvgsGKttLtqalkgeel..kYkktqaiefsdaviDtPGeylenrklysa 56 kil++G +g+GKt L ++ + + +Y +t i+ ++++D G+ ++ + + +a FUN_000371-T1 11 KILILGDSGVGKTCLIFRFIEDIFsdSYISTIGIDCRSRTVDLDGKRVRLQIWDTA 66 8**************999877654337***************99998876665444 PP >> AAA_7 P-loop containing dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 3.5e-05 0.052 34 65 .. 10 41 .. 4 54 .. 0.81 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 3.5e-05 AAA_7 34 kpvLlvGptGtGKtviikdllkkldkekylsl 65 +++L+ G++G+GKt++i ++++ + +++y+s+ FUN_000371-T1 10 YKILILGDSGVGKTCLIFRFIEDIFSDSYIST 41 789****************9999888887654 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 5.8e-05 0.088 8 68 .. 12 76 .. 9 128 .. 0.80 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 5.8e-05 AAA_22 8 lvltGesGtGKTtllrrlleqldee.ddsvvlvelpsst...spkdllrellralglelekelsk 68 +++ G+sG+GKT l+ r++e ++ s++ ++++s t + k+++ ++ g+e+ +l++ FUN_000371-T1 12 ILILGDSGVGKTCLIFRFIEDIFSDsYISTIGIDCRSRTvdlDGKRVRLQIWDTAGQERFRTLTS 76 7899***********99999887555666669999999987777777777777777766664444 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 5.3e-05 0.079 3 23 .. 10 31 .. 8 120 .. 0.86 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.3e-05 AAA_24 3 lkvliyGpsgiGKTtlaksl.p 23 +k+li G+sg+GKT l++++ + FUN_000371-T1 10 YKILILGDSGVGKTCLIFRFiE 31 79***************99852 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 5.1e-05 0.076 27 66 .. 12 57 .. 10 176 .. 0.66 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 5.1e-05 AAA_16 27 vlvsGeaGvGKSalvrellralera..alvlsgkcdelqrg....l 66 +l+ G++GvGK+ l+ ++ + + + + ++ ++c++ + + FUN_000371-T1 12 ILILGDSGVGKTCLIFRFIEDIFSDsyISTIGIDCRSRTVDldgkR 57 79*************9999888888554447777766633333331 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 8.6e-05 0.13 3 71 .. 8 67 .. 6 75 .. 0.80 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 8.6e-05 Septin 3 ieftlmvvGesglGkstlinslfetdlieerkieeasekikktveikkkkveieedgvklnltvvDtpg 71 +++ +++ G+sg+Gk+ li ++e+ ++ +t+ i+ ++ +++ dg +++l++ Dt g FUN_000371-T1 8 LTYKILILGDSGVGKTCLIFRFIEDIFSDS---------YISTIGIDCRSRTVDLDGKRVRLQIWDTAG 67 57889**************98876554444.........446778888888888888888888999877 PP >> RXYLT1_N RXYLT1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.00013 0.19 59 106 .. 82 129 .. 60 164 .. 0.88 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00013 RXYLT1_N 59 venlvLvlngreeekikaakqwLdelkslkklknvavvllGne.qCene 106 + +vLv + +e+ k+ +qwL+++++ +nv +l+Gn+ +Ce+e FUN_000371-T1 82 AMGIVLVYDITTEDSFKNITQWLQNIDEN-ASRNVCKILVGNKlDCEDE 129 5679**********************996.7799999999997578765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (183 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 858 (0.0335878); expected 510.9 (0.02) Passed bias filter: 694 (0.0271677); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 1871.09 // Query: FUN_000372-T1 [L=193] Description: FUN_000372 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-65 217.6 1.3 1.1e-64 217.4 1.3 1.0 1 Ras Ras family 1.3e-31 109.8 0.4 1.3e-31 109.8 0.4 1.4 2 Roc Ras of Complex, Roc, domain of DAPkinase 5.6e-15 55.7 0.3 6.8e-15 55.5 0.3 1.1 1 Arf ADP-ribosylation factor family 0.00062 20.1 0.3 1 9.7 0.0 2.2 2 RsgA_GTPase RsgA GTPase 0.0016 18.6 0.8 0.002 18.3 0.2 1.4 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.0017 18.3 0.3 0.0022 18.0 0.3 1.2 1 Gtr1_RagA Gtr1/RagA G protein conserved region 0.0062 17.1 0.1 0.012 16.2 0.1 1.5 2 MMR_HSR1 50S ribosome-binding GTPase ------ inclusion threshold ------ 0.13 12.9 0.2 0.29 11.8 0.2 1.6 1 Tor_FN3_2nd Tyrosine-protein kinase receptor torso, second F 0.14 12.7 0.7 0.31 11.6 0.7 1.6 1 DUF3963 Protein of unknown function (DUF3963) 0.2 12.6 0.3 3.7 8.5 0.1 2.5 2 AAA ATPase family associated with various cellular a Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 217.4 1.3 4.3e-68 1.1e-64 1 161 [. 10 170 .. 10 171 .. 0.99 Alignments for each domain: == domain 1 score: 217.4 bits; conditional E-value: 4.3e-68 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwlee 96 klvlvGdsgvGK+++l+rf +++F +++++ ig+dfk++t+e+dgk++klqiw TAGqerfr+++++yyr a+gi+lvydit+ +sfen+k+w+++ FUN_000372-T1 10 KLVLVGDSGVGKTCVLFRFSEDDFISTSIASIGIDFKVRTIELDGKKIKLQIWVTAGQERFRTITTSYYRAAMGIMLVYDITNDKSFENIKNWIRN 105 89********************************************************************************************** PP Ras 97 ikrvaeenvpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 i+++a+++v+ +++Gnk+D+e++r+v++e+g +la e+g+kf+etSAk++ nveeaf +l+r+i+ FUN_000372-T1 106 IEEHASSDVEKMVLGNKCDMEDRRAVTKERGTQLATEYGIKFMETSAKSSINVEEAFFTLARDIK 170 **************************************************************996 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.8 0.4 5e-35 1.3e-31 1 119 [] 10 124 .. 10 124 .. 0.92 2 ? -2.8 0.0 4 1e+04 20 42 .. 131 153 .. 128 162 .. 0.60 Alignments for each domain: == domain 1 score: 109.8 bits; conditional E-value: 5e-35 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srsse 93 K+vl+GdsgvGKt++l rf ed+f +++ + ig+df+ +++ +++g kkikl+iW taGqerfr+++++yyr+a +++lv+d ++s+e FUN_000372-T1 10 KLVLVGDSGVGKTCVLFRFSEDDFISTSIASIGIDFKVRTI-ELDG-------KKIKLQIWVTAGQERFRTITTSYYRAAMGIMLVYDitnDKSFE 97 99**********************************98876.4444.......78*********************************87666889 PP Roc 94 nlkeWlkelkevagks.pvilvgnkiD 119 n+k+W+++++e+a+++ +++gnk+D FUN_000372-T1 98 NIKNWIRNIEEHASSDvEKMVLGNKCD 124 ************99774789******9 PP == domain 2 score: -2.8 bits; conditional E-value: 4 Roc 20 vedefdekekstigvdflskelt 42 v++e ++ + +g++f++ +++ FUN_000372-T1 131 VTKERGTQLATEYGIKFMETSAK 153 55555566666777877776553 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.5 0.3 2.7e-18 6.8e-15 15 167 .. 9 162 .. 4 175 .. 0.79 Alignments for each domain: == domain 1 score: 55.5 bits; conditional E-value: 2.7e-18 Arf 15 lrilllGLDnaGKtTilkklkleelvt.tiPT..igfnveevei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLk 105 ++++l+G + GKt +l +++++++ + i i f+v+++e k++k+++w Gqe+ R + +Y+++ +++ v D ++ + +e+ k+ ++ FUN_000372-T1 9 FKLVLVGDSGVGKTCVLFRFSEDDFIStSIASigIDFKVRTIELdgKKIKLQIWVTAGQERFRTITTSYYRAAMGIMLVYDITNDKSFENIKNWIR 104 6899******************99876244541156899998876699*********************************************999 PP Arf 106 alleeeelkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkegl 167 ++ ee+ +++ +vl+NK D+++ ++++ g + ++ ++ +++sa + +++e++ FUN_000372-T1 105 NI-EEHASSDVEKMVLGNKCDMEDRR---AVTKERGTQLATEYGIKFMETSAKSSINVEEAF 162 96.778899*************9753...344444444444455555555555555555555 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.00075 1.9 109 129 .. 11 31 .. 8 42 .. 0.80 2 ! 9.7 0.0 0.00039 1 47 104 .. 107 165 .. 71 185 .. 0.74 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00075 RsgA_GTPase 109 tvllGqSGvGKStLinallpe 129 vl+G SGvGK+ + ++ ++ FUN_000372-T1 11 LVLVGDSGVGKTCVLFRFSED 31 59*********9988776665 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00039 RsgA_GTPase 47 vlaeesgiepvivlnKiDlleeee.eleelkkeyealgyevllvsaktgegleelkell 104 +s++e +++ nK D+ ++++ + e+ + ++++g++++ +sak++ ++ee l FUN_000372-T1 107 EEHASSDVEKMVLGNKCDMEDRRAvTKERGTQLATEYGIKFMETSAKSSINVEEAFFTL 165 4456789999************99666777788899***********998888643333 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 4.5 1.2e+04 7 19 .. 12 24 .. 10 27 .. 0.80 2 ! 18.3 0.2 7.7e-07 0.002 54 178 .. 42 161 .. 36 174 .. 0.76 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 4.5 GTP_EFTU 7 giighvDhGKtTl 19 +++g+ GKt++ FUN_000372-T1 12 VLVGDSGVGKTCV 24 6789999999986 PP == domain 2 score: 18.3 bits; conditional E-value: 7.7e-07 GTP_EFTU 54 GiTiksaavsfetkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveG....vepqteevlrlarklgvpiivviNKmDrvdeaelkevvee 145 Gi k+ ++++++kk ++++ t G + F ++ ++++ g +lv d++++ ++ ++++ + +v+ +v+ NK+D+ + + v +e FUN_000372-T1 42 GIDFKVRTIELDGKKIKLQIWVTAGQERFRTITTSYYRAAMGIMLVYDITNDksfeNIKNWIRNIEEHASSDVEKMVLGNKCDME---DRRAVTKE 134 677788999999**************************************9944432333444555666678889*********9...44555555 PP GTP_EFTU 146 vkeellekvgekgekevpvvpgSalkgegvkel 178 ++l +++ ++++ +Sa++ +v+e FUN_000372-T1 135 RGTQLATEY------GIKFMETSAKSSINVEEA 161 555563333......356888888888888764 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.3 8.5e-07 0.0022 1 131 [. 10 130 .. 10 165 .. 0.72 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 8.5e-07 Gtr1_RagA 1 kvLLmGksksGKsSir.sviFsnyspkdtlrlgatidveksevrflgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedl 95 k++L+G s+ GK+++ + + ++ + ++g+ +v e+ ++++l++w Gqe+f + + + ++ ++ v D++ ++++ FUN_000372-T1 10 KLVLVGDSGVGKTCVLfRFSEDDFISTSIASIGIDFKVRTIELD-GKKIKLQIWVTAGQERFRTIT-----TSYYRAAMGIMLVYDIT---NDKSF 96 799**********9741333345667777777777777777774.678************998876.....55677778889999**9...78899 PP Gtr1_RagA 96 arlketlealsev.speakvfvlihKvDlisedkree 131 +++k+ ++++ e+ s +++ vl +K+D +++ FUN_000372-T1 97 ENIKNWIRNIEEHaSSDVEKMVLGNKCDMEDRR---A 130 999999999987537899999*******85432...2 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.1 4.6e-06 0.012 2 102 .. 11 109 .. 10 122 .. 0.72 2 ? -1.8 0.0 1.9 4.8e+03 20 52 .. 119 149 .. 111 172 .. 0.63 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 4.6e-06 MMR_HSR1 2 vaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkg..kkielvDtpGliegaseee.gleraflaieeadlillvvd..aeegltel 92 ++vG + vGK+ ++ + ++++ i ++++ d + +++el+g k++++ t+G e ++ ++ ++ + a i+lv d ++++++++ FUN_000372-T1 11 LVLVGDSGVGKTCVLFRFSEDDFISTSIASIGIDFKVRTIELDGkkIKLQIWVTAG-QE----RFrTITTSYY--RAAMGIMLVYDitNDKSFENI 99 689**************************************887235578999999.55....3335555555..346779999997633456666 PP MMR_HSR1 93 deeleellee 102 ++ ++++ e+ FUN_000372-T1 100 KNWIRNIEEH 109 5555555433 PP == domain 2 score: -1.8 bits; conditional E-value: 1.9 MMR_HSR1 20 tgkkaivsdypgtTrdpnegklelkgkkielvD 52 +g+k+ ++d +T+++ + + ++ i+++ FUN_000372-T1 119 LGNKCDMEDRRAVTKERGTQLAT--EYGIKFME 149 45566677777777776665444..34455444 PP >> Tor_FN3_2nd Tyrosine-protein kinase receptor torso, second FN3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.2 0.00011 0.29 30 71 .. 85 126 .. 60 137 .. 0.82 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00011 Tor_FN3_2nd 30 dlcfdianicqntnmkhakiwptahpsfdvenlvlndeceih 71 l++di+n n+k h s dve++vl ++c++ FUN_000372-T1 85 MLVYDITNDKSFENIKNWIRNIEEHASSDVEKMVLGNKCDME 126 588999999999999988888899***************985 PP >> DUF3963 Protein of unknown function (DUF3963) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.7 0.00012 0.31 4 23 .. 87 106 .. 84 108 .. 0.85 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00012 DUF3963 4 iyaiFiEkYFgDiqKWiRNi 23 +y i +k F +i+ WiRNi FUN_000372-T1 87 VYDITNDKSFENIKNWIRNI 106 677777899**********9 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.1 0.0015 3.7 2 63 .. 12 87 .. 11 92 .. 0.71 2 ? 1.1 0.0 0.27 7e+02 17 35 .. 138 156 .. 136 180 .. 0.79 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0015 AAA 2 llyGppGtGKTllakavake..l...........gaefveisgselv.skyvgesekklrelfeeakkkapsvifi 63 +l+G G+GKT + ++ + +++ +e++g+++ + +v ++++++r + ++ + a ++++ FUN_000372-T1 12 VLVGDSGVGKTCVLFRFSEDdfIstsiasigidfKVRTIELDGKKIKlQIWVTAGQERFRTITTSYYRAAMGIMLV 87 79*********99887777754133444444444477888888888877799999999999888876666666665 PP == domain 2 score: 1.1 bits; conditional E-value: 0.27 AAA 17 avakelgaefveisgselv 35 +a+e g++f+e+s+++ + FUN_000372-T1 138 QLATEYGIKFMETSAKSSI 156 6899**********99877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (193 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1125 (0.0440399); expected 510.9 (0.02) Passed bias filter: 745 (0.0291642); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.61 # Mc/sec: 1285.28 // Query: FUN_000373-T1 [L=179] Description: FUN_000373 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-44 150.4 0.2 1.2e-28 100.2 0.0 2.0 2 Ras Ras family 8e-24 84.7 0.1 3.5e-23 82.6 0.0 1.8 2 Roc Ras of Complex, Roc, domain of DAPkinase 2e-11 44.1 0.0 3.2e-07 30.5 0.0 2.1 2 Arf ADP-ribosylation factor family 0.0044 17.3 0.0 1.3 9.3 0.0 2.1 2 RsgA_GTPase RsgA GTPase 0.0056 17.0 0.0 0.0077 16.6 0.0 1.2 1 NTPase_1 NTPase 0.0072 16.9 0.0 0.009 16.6 0.0 1.4 1 MMR_HSR1 50S ribosome-binding GTPase 0.0097 16.2 0.0 0.016 15.5 0.0 1.4 1 Cas_Csm6_CARF Cas_Csm6 CARF domain ------ inclusion threshold ------ 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 Gtr1_RagA Gtr1/RagA G protein conserved region 0.017 15.0 0.0 0.025 14.4 0.0 1.2 1 SRPRB Signal recognition particle receptor beta subu 0.019 15.0 0.1 11 6.0 0.0 3.0 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.031 14.3 0.0 0.05 13.6 0.0 1.3 1 AAA_7 P-loop containing dynein motor region 0.043 14.6 0.0 0.075 13.8 0.0 1.4 1 AAA_22 AAA domain 0.069 13.3 0.0 0.088 13.0 0.0 1.3 1 AAA_24 AAA domain 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 Septin Septin 0.092 13.7 0.0 0.11 13.5 0.0 1.3 1 AAA_16 AAA ATPase domain 0.094 13.0 0.0 0.24 11.7 0.0 1.6 2 PduV-EutP Ethanolamine utilisation - propanediol utilisa 0.23 11.6 0.0 0.39 10.9 0.0 1.4 1 nSTAND3 Novel STAND NTPase 3 0.24 12.1 0.0 0.42 11.4 0.0 1.5 1 DUF1327 Protein of unknown function (DUF1327) Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.2 0.0 8.4e-32 1.2e-28 1 73 [. 11 83 .. 11 85 .. 0.98 2 ! 49.0 0.1 4.7e-16 6.6e-13 101 161 .. 85 145 .. 83 146 .. 0.95 Alignments for each domain: == domain 1 score: 100.2 bits; conditional E-value: 8.4e-32 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgae 73 k++++GdsgvGK++l++rf+++ F+++y+sTig+d ++tv++dgk+v+lqiwDTAGqerfr+l++ay+rga+ FUN_000373-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTIGIDCRSRTVDLDGKRVRLQIWDTAGQERFRTLTSAYFRGAM 83 89********************************************************************997 PP == domain 2 score: 49.0 bits; conditional E-value: 4.7e-16 Ras 101 aeenvpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 a++nv +lvGnk D+e++r++++ +g +++++ +l+f+etSA+t e+v+eaf++++r+i+ FUN_000373-T1 85 ASRNVCKILVGNKLDCEDERAIDKFRGISMSENAELEFFETSARTGEGVSEAFMAVARQIK 145 457899*****************************************************97 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.6 0.0 2.5e-26 3.5e-23 1 81 [. 11 83 .. 11 86 .. 0.92 2 ? -0.1 0.0 1.1 1.5e+03 107 119 .] 87 99 .. 82 99 .. 0.74 Alignments for each domain: == domain 1 score: 82.6 bits; conditional E-value: 2.5e-26 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaa 81 K+++lGdsgvGKt+l+ rf+ed f++++ stig+d s+++ +++g k+++l+iWDtaGqerfr+l++ y+r+a FUN_000373-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTIGIDCRSRTV-DLDG-------KRVRLQIWDTAGQERFRTLTSAYFRGAM 83 9***********************************99986.4444.......789**********************985 PP == domain 2 score: -0.1 bits; conditional E-value: 1.1 Roc 107 gkspvilvgnkiD 119 + + ilvgnk+D FUN_000373-T1 87 RNVCKILVGNKLD 99 455679*****98 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 0.0 2.2e-10 3.2e-07 14 80 .. 9 80 .. 3 85 .. 0.84 2 ! 12.1 0.0 0.0001 0.14 113 173 .. 86 143 .. 81 144 .. 0.85 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 2.2e-10 Arf 14 elrilllGLDnaGKtTilkklkleelvt.tiPTigfnveevei....knlkftvwDvGGqeklRplWknYfe 80 ++il+lG + GKt ++ ++ ++ +++ i Tig + ++ ++ k +++++wD Gqe+ R l + Yf+ FUN_000373-T1 9 TYKILILGDSGVGKTCLIFRFIEDIFSDsYISTIGIDCRSRTVdldgKRVRLQIWDTAGQERFRTLTSAYFR 80 68*******************99998764899*9987664333335599*********************97 PP == domain 2 score: 12.1 bits; conditional E-value: 0.0001 Arf 113 lkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkeglewlses 173 +++ ++++NK D ++ e+ i + g++ ++ +le +++sa +geg++e++ ++++ FUN_000373-T1 86 SRNVCKILVGNKLDCED---ERAIDKFRGISMSENAELEFFETSARTGEGVSEAFMAVARQ 143 578888999*****986...67788888999899********************9888766 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.0 0.00094 1.3 109 127 .. 12 30 .. 5 42 .. 0.82 2 ! 6.1 0.0 0.0087 12 51 104 .. 86 140 .. 79 152 .. 0.79 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00094 RsgA_GTPase 109 tvllGqSGvGKStLinall 127 +++lG SGvGK+ Li ++ FUN_000373-T1 12 ILILGDSGVGKTCLIFRFI 30 4679**********97665 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0087 RsgA_GTPase 51 esgiepvivlnKiDlleeeeeleelk..keyealgyevllvsaktgegleelkell 104 ++++ ++v nK+D+ +e++ +++++ + e++++e++ +sa+tgeg+ e ++ FUN_000373-T1 86 SRNVCKILVGNKLDCEDERA-IDKFRgiSMSENAELEFFETSARTGEGVSEAFMAV 140 5677789999*****99999.66664116789999************998765555 PP >> NTPase_1 NTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 5.4e-06 0.0077 1 57 [. 11 70 .. 11 97 .. 0.77 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 5.4e-06 NTPase_1 1 kifiTGepGvGKtTlvekvaeklkek.gvkvgGfyteevr..eggkrigFkivdlasgee 57 ki+i G +GvGKt l+ + +e + ++ +++ G+ ++ + +gkr++ +i d a +e+ FUN_000373-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDsYISTIGIDCRSRTvdLDGKRVRLQIWDTAGQER 70 68999***********9999887665267899**9986554489*********9976555 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 6.3e-06 0.009 1 72 [. 11 80 .. 11 145 .. 0.75 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 6.3e-06 MMR_HSR1 1 rvaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkg..kkielvDtpGliegaseee.glerafla 72 ++ i+G + vGK+ Li + +++ s + d ++++l+g +++++Dt+G e ++ l++a+ + FUN_000373-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTIGIDCRSRTVDLDGkrVRLQIWDTAG-QE----RFrTLTSAYFR 80 589******************9777777777777888888887763356899*****.54....22245555443 PP >> Cas_Csm6_CARF Cas_Csm6 CARF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 1.2e-05 0.016 34 54 .. 158 178 .. 144 179 .] 0.92 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.2e-05 Cas_Csm6_CARF 34 pdaeillnvssGtPqmksalv 54 +d++i ln s G Pqm+sa++ FUN_000373-T1 158 EDTTIPLNPSHGSPQMQSACC 178 799*****************9 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 1.6e-05 0.023 1 63 [. 11 73 .. 11 94 .. 0.76 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 1.6e-05 Gtr1_RagA 1 kvLLmGksksGKsSirsviFsnyspkdtlrlgatidveksevrflg.nltlnlwdlgGqekfld 63 k+L++G s+ GK+++ F + + d ++ id +v + g + l++wd Gqe+f + FUN_000373-T1 11 KILILGDSGVGKTCLIFR-FIEDIFSDSYISTIGIDCRSRTVDLDGkRVRLQIWDTAGQERFRT 73 89************7532.333445566666666777778887765269***********9865 PP >> SRPRB Signal recognition particle receptor beta subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 1.8e-05 0.025 5 61 .. 11 73 .. 8 93 .. 0.83 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1.8e-05 SRPRB 5 tviiaGlsdsGKtslftkLttdsvrktvtSq..epsvalry....kgkkltliDfPGhdklrq 61 +++i G s GKt l+ + +d ++++S + + + k +l++ D G++++r+ FUN_000373-T1 11 KILILGDSGVGKTCLIFRFIEDIFSDSYISTigIDCRSRTVdldgKRVRLQIWDTAGQERFRT 73 699***************************96656666666777777888999*******997 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.0081 11 54 86 .. 43 75 .. 7 85 .. 0.74 2 ? 4.4 0.0 0.024 34 121 186 .. 88 144 .. 80 146 .. 0.64 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0081 GTP_EFTU 54 GiTiksaavsfetkkrlinliDtPGhvdFvkev 86 Gi s +v +++k+ ++++ Dt G + F + FUN_000373-T1 43 GIDCRSRTVDLDGKRVRLQIWDTAGQERFRTLT 75 555666777777888888888888888887655 PP == domain 2 score: 4.4 bits; conditional E-value: 0.024 GTP_EFTU 121 gvpiivviNKmDrvdeaelkevveevkeellekvgekgekevpvvpgSalkgegvkellealvell 186 +v i+v NK+D +++ + + ++ + e+ e +++ +Sa +gegv e + a+ + + FUN_000373-T1 88 NVCKILVGNKLDCE-DERAIDKFRGIS------MSEN--AELEFFETSARTGEGVSEAFMAVARQI 144 55566667777777.333333333333......1222..46899***********99888777665 PP >> AAA_7 P-loop containing dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 3.5e-05 0.05 34 65 .. 10 41 .. 4 54 .. 0.81 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 3.5e-05 AAA_7 34 kpvLlvGptGtGKtviikdllkkldkekylsl 65 +++L+ G++G+GKt++i ++++ + +++y+s+ FUN_000373-T1 10 YKILILGDSGVGKTCLIFRFIEDIFSDSYIST 41 789****************9999888887654 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 5.3e-05 0.075 8 75 .. 12 83 .. 9 95 .. 0.79 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 5.3e-05 AAA_22 8 lvltGesGtGKTtllrrlleqldee.ddsvvlvelpsst...spkdllrellralglelekelskeellaal 75 +++ G+sG+GKT l+ r++e ++ s++ ++++s t + k+++ ++ g+e+ +l++ ++ a+ FUN_000373-T1 12 ILILGDSGVGKTCLIFRFIEDIFSDsYISTIGIDCRSRTvdlDGKRVRLQIWDTAGQERFRTLTSAYFRGAM 83 7899***********999999875566677799999999988888888888888888777766666666555 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 6.2e-05 0.088 3 23 .. 10 31 .. 8 94 .. 0.85 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 6.2e-05 AAA_24 3 lkvliyGpsgiGKTtlaksl.p 23 +k+li G+sg+GKT l++++ + FUN_000373-T1 10 YKILILGDSGVGKTCLIFRFiE 31 79**************999852 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 8.4e-05 0.12 3 71 .. 8 67 .. 6 77 .. 0.80 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 8.4e-05 Septin 3 ieftlmvvGesglGkstlinslfetdlieerkieeasekikktveikkkkveieedgvklnltvvDtpg 71 +++ +++ G+sg+Gk+ li ++e+ ++ +t+ i+ ++ +++ dg +++l++ Dt g FUN_000373-T1 8 LTYKILILGDSGVGKTCLIFRFIEDIFSDS---------YISTIGIDCRSRTVDLDGKRVRLQIWDTAG 67 57889**************98876554444.........446778888888888888888899999877 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 7.6e-05 0.11 27 62 .. 12 49 .. 10 153 .. 0.72 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 7.6e-05 AAA_16 27 vlvsGeaGvGKSalvrellralera..alvlsgkcdel 62 +l+ G++GvGK+ l+ ++ + + + + ++ ++c++ FUN_000373-T1 12 ILILGDSGVGKTCLIFRFIEDIFSDsyISTIGIDCRSR 49 79*************99888887775544466666666 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00017 0.24 3 49 .. 11 59 .. 9 69 .. 0.82 2 ? -1.6 0.0 2.1 3e+03 98 136 .. 97 135 .. 74 140 .. 0.59 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00017 PduV-EutP 3 killiGkvgsGKttLtqalkgeel..kYkktqaiefsdaviDtPGeyle 49 kil++G +g+GKt L ++ + + +Y +t i+ ++++D G+ ++ FUN_000373-T1 11 KILILGDSGVGKTCLIFRFIEDIFsdSYISTIGIDCRSRTVDLDGKRVR 59 8**************999877554237999*99***9999999987665 PP == domain 2 score: -1.6 bits; conditional E-value: 2.1 PduV-EutP 98 kidlaedeeeieaaeel.LklAGakkifkvsavekegiee 136 k+d + de +i++ + +++ + f++sa + eg+ e FUN_000373-T1 97 KLDCE-DERAIDKFRGIsMSENAELEFFETSARTGEGVSE 135 44444.5555555443313333334568888888887766 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00027 0.39 20 46 .. 12 38 .. 7 67 .. 0.85 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00027 nSTAND3 20 viitGepGiGKttlaemLalklldegy 46 ++i+G++G+GKt l + + +++y FUN_000373-T1 12 ILILGDSGVGKTCLIFRFIEDIFSDSY 38 79************9999988888776 PP >> DUF1327 Protein of unknown function (DUF1327) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00029 0.42 43 74 .. 113 146 .. 81 158 .. 0.84 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00029 DUF1327 43 drveGaalefyeaeakk..svkqvflevaeklse 74 e a lef+e+ a+ v f+ va ++ e FUN_000373-T1 113 SMSENAELEFFETSARTgeGVSEAFMAVARQIKE 146 45799**********9633699*******99887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 509 (0.0199256); expected 510.9 (0.02) Passed bias filter: 471 (0.0184381); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1789.78 // Query: FUN_000374-T1 [L=2230] Description: FUN_000374 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-44 147.4 262.6 0.0024 18.9 0.9 29.5 28 zf-C2H2_4 C2H2-type zinc finger 5.6e-39 133.2 0.0 1.6e-38 131.7 0.0 1.8 1 PRDM2_PR PR domain zinc finger protein 2, PR domai 4.1e-24 84.1 276.9 0.0013 19.5 1.0 29.7 28 zf-C2H2 Zinc finger, C2H2 type 9.9e-15 54.8 144.2 0.0095 16.6 3.5 23.9 24 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding 1.3e-09 38.2 22.2 8.9e-07 29.2 4.5 24.3 25 zf-C2H2_6 C2H2-type zinc finger 1.5e-09 38.7 0.0 1.5e-09 38.7 0.0 4.8 4 SET SET domain 6.9e-05 22.9 6.6 0.00042 20.4 0.4 20.5 20 zf-C2H2_11 zinc-finger C2H2-type 0.00058 20.6 18.1 0.006 17.4 2.8 28.8 27 zf-H2C2_2 Zinc-finger double domain 0.0029 17.8 0.4 0.0029 17.8 0.4 12.4 15 zf-C2H2_7th_ZNF462 Zinc finger protein 462, seventh C2H2 zin 0.0043 17.4 0.2 3.5 7.9 0.0 3.2 2 DddA-like Double-stranded DNA deaminase toxin A ------ inclusion threshold ------ 0.011 16.0 0.1 0.011 16.0 0.1 11.0 11 TSTD2_N TSTD2 protein N-terminal domain 0.015 16.0 2.2 0.015 16.0 2.2 15.4 17 zf-Di19 Drought induced 19 protein (Di19), zinc-b 0.018 15.5 0.1 0.053 14.0 0.1 1.7 1 HVO_2525_N HVO_2525, N-terminal 0.7 10.3 0.0 0.7 10.3 0.0 6.5 7 zf-FPG_IleRS Zinc finger found in FPG and IleRS Domain annotation for each model (and alignments): >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 6.7 0.00073 1.3 1 23 [. 305 327 .. 305 328 .. 0.93 2 ? 5.8 3.8 0.022 41 1 24 [] 333 356 .. 333 356 .. 0.91 3 ! 11.6 0.1 0.00029 0.54 2 19 .. 363 380 .. 362 381 .. 0.94 4 ? 5.9 0.2 0.02 36 7 23 .. 394 410 .. 391 411 .. 0.91 5 ! 16.9 2.2 6e-06 0.011 1 23 [. 418 440 .. 418 441 .. 0.97 6 ! 18.9 0.9 1.3e-06 0.0024 2 23 .. 457 478 .. 456 479 .. 0.97 7 ! 9.9 0.3 0.001 1.9 3 24 .] 487 507 .. 485 507 .. 0.80 8 ? 6.3 0.2 0.015 28 2 24 .] 514 536 .. 513 536 .. 0.92 9 ! 9.1 3.0 0.002 3.6 2 23 .. 591 612 .. 590 613 .. 0.94 10 ! 18.3 3.6 2.2e-06 0.004 1 23 [. 698 720 .. 698 721 .. 0.97 11 ! 12.2 3.2 0.00019 0.34 1 24 [] 762 784 .. 762 784 .. 0.95 12 ! 12.2 3.2 0.00019 0.34 1 24 [] 832 854 .. 832 854 .. 0.95 13 ! 13.2 1.0 8.9e-05 0.16 1 24 [] 934 956 .. 934 957 .. 0.88 14 ? 5.1 0.2 0.037 68 1 24 [] 988 1011 .. 988 1011 .. 0.94 15 ! 11.8 0.3 0.00026 0.47 1 22 [. 1018 1039 .. 1018 1041 .. 0.89 16 ! 10.3 2.2 0.00081 1.5 1 20 [. 1047 1066 .. 1047 1066 .. 0.93 17 ! 15.0 0.3 2.5e-05 0.045 1 23 [. 1167 1189 .. 1167 1190 .. 0.96 18 ! 18.3 2.6 2.1e-06 0.0039 1 23 [. 1196 1218 .. 1196 1219 .. 0.96 19 ! 7.6 2.2 0.0057 10 1 22 [. 1229 1250 .. 1229 1252 .. 0.92 20 ! 11.5 4.7 0.00033 0.6 1 24 [] 1286 1309 .. 1286 1309 .. 0.95 21 ! 14.7 2.5 3e-05 0.054 1 24 [] 1332 1355 .. 1332 1355 .. 0.96 22 ! 12.6 0.9 0.00014 0.26 2 24 .] 1378 1400 .. 1377 1400 .. 0.95 23 ! 9.4 0.5 0.0016 2.8 2 24 .] 1440 1462 .. 1439 1462 .. 0.94 24 ! 10.7 5.1 0.00058 1.1 1 24 [] 1538 1561 .. 1538 1561 .. 0.95 25 ! 9.7 5.2 0.0012 2.2 2 24 .] 1616 1638 .. 1615 1638 .. 0.94 26 ? 0.3 5.8 1.3 2.4e+03 5 24 .] 1731 1750 .. 1730 1750 .. 0.97 27 ? 6.0 6.7 0.019 35 1 24 [] 1804 1827 .. 1804 1827 .. 0.94 28 ? 5.0 1.1 0.041 74 1 19 [. 1892 1910 .. 1892 1918 .. 0.80 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00073 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 ++C +C++sF+s+++L+ H + h FUN_000374-T1 305 WRCIHCDRSFKSQHSLHFHKNIH 327 68*****************9998 PP == domain 2 score: 5.8 bits; conditional E-value: 0.022 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 f C+iCgk F+ + + +rH + H FUN_000374-T1 333 FTCRICGKAFTHPASRNRHYHSFH 356 89********99999999*98877 PP == domain 3 score: 11.6 bits; conditional E-value: 0.00029 zf-C2H2_4 2 kCpiCgksFsskkaLrrH 19 C+iCgk Fs+ ++L++H FUN_000374-T1 363 VCKICGKAFSDDNSLKSH 380 6****************9 PP == domain 4 score: 5.9 bits; conditional E-value: 0.02 zf-C2H2_4 7 gksFsskkaLrrHlkkh 23 ++sF+s aL++H++ h FUN_000374-T1 394 DQSFVSAFALSKHMRVH 410 689************99 PP == domain 5 score: 16.9 bits; conditional E-value: 6e-06 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 ++C++C k Fss+k+L+rH+k h FUN_000374-T1 418 YQCKQCLKFFSSSKSLNRHIKLH 440 89*******************99 PP == domain 6 score: 18.9 bits; conditional E-value: 1.3e-06 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkh 23 kC +Cg +Fss aL++H+++h FUN_000374-T1 457 KCQHCGNVFSSAVALSNHMRMH 478 7********************9 PP == domain 7 score: 9.9 bits; conditional E-value: 0.001 zf-C2H2_4 3 CpiCgksFsskka.LrrHlkkhH 24 CpiC s++++ L rH++k H FUN_000374-T1 487 CPIC--KVSNYSGsLARHMRKKH 507 ****..55555555*******99 PP == domain 8 score: 6.3 bits; conditional E-value: 0.015 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 +C Cgk++++k+ L H++ H FUN_000374-T1 514 RCGKCGKVCADKRVLAVHIAIRH 536 7*****************98777 PP == domain 9 score: 9.1 bits; conditional E-value: 0.002 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkh 23 C+iC ++F+s+k ++ H ++h FUN_000374-T1 591 SCEICFAVFPSSKLMHCHRASH 612 6******************999 PP == domain 10 score: 18.3 bits; conditional E-value: 2.2e-06 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 f+C+iC+ksFs+ ++Lr+H ++h FUN_000374-T1 698 FCCTICKKSFSTVTSLRSHKASH 720 89*******************99 PP == domain 11 score: 12.2 bits; conditional E-value: 0.00019 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 f+C C+k+F++ ++Lr+H k+hH FUN_000374-T1 762 FRCLDCNKTFPTGRSLRSH-KSHH 784 89*****************.8887 PP == domain 12 score: 12.2 bits; conditional E-value: 0.00019 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 f+C C+k+F++ ++Lr+H k+hH FUN_000374-T1 832 FRCLDCNKTFPTGRSLRSH-KSHH 854 89*****************.8887 PP == domain 13 score: 13.2 bits; conditional E-value: 8.9e-05 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 f C Cgk F sk++L rH k hH FUN_000374-T1 934 FSCGECGKAFISKRNLARH-KGHH 956 79*****************.5554 PP == domain 14 score: 5.1 bits; conditional E-value: 0.037 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 ++C+ C +sF +aL +H ++ H FUN_000374-T1 988 YECSTCLESFYGGSALVNHQRRIH 1011 89********99999*****9987 PP == domain 15 score: 11.8 bits; conditional E-value: 0.00026 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkk 22 f Cp+C+k F ++ +L+ H + FUN_000374-T1 1018 FICPFCDKIFLTRASLLLHKQD 1039 89**************999876 PP == domain 16 score: 10.3 bits; conditional E-value: 0.00081 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHl 20 f C++C+ +Fssk++ ++Hl FUN_000374-T1 1047 FTCKHCNGRFSSKYSRNNHL 1066 89*************88896 PP == domain 17 score: 15.0 bits; conditional E-value: 2.5e-05 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 + C++C ++F++k +L++H ++h FUN_000374-T1 1167 YLCDVCFEPFKTKIGLNNHKRSH 1189 78*******************99 PP == domain 18 score: 18.3 bits; conditional E-value: 2.1e-06 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 f C+iC++ F+sk++LrrH k h FUN_000374-T1 1196 FICSICHRGFVSKRNLRRHRKLH 1218 89******************999 PP == domain 19 score: 7.6 bits; conditional E-value: 0.0057 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkk 22 f C C+k+F s+++L++H k+ FUN_000374-T1 1229 FACFTCSKPFQSYSGLYKHRKR 1250 78999**************997 PP == domain 20 score: 11.5 bits; conditional E-value: 0.00033 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 ++C +C k F +++LrrH+ k H FUN_000374-T1 1286 WQCQYCEKEFQKRCNLRRHVSKKH 1309 69*******************999 PP == domain 21 score: 14.7 bits; conditional E-value: 3e-05 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 +kC +C ++F++ +L+rH++k H FUN_000374-T1 1332 WKCQHCERQFRTEFGLLRHVEKRH 1355 69*******************998 PP == domain 22 score: 12.6 bits; conditional E-value: 0.00014 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 C +Cg F+s +++r+H+ + H FUN_000374-T1 1378 NCLYCGNEFNSIHGIRKHVSRKH 1400 7*******************999 PP == domain 23 score: 9.4 bits; conditional E-value: 0.0016 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 +C +C++ F++ ++ ++H+ +H FUN_000374-T1 1440 RCQYCNRGFPTVSKRYKHVMLVH 1462 7*************999*99988 PP == domain 24 score: 10.7 bits; conditional E-value: 0.00058 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 f+C++C+k F +k++ rrH ++ H FUN_000374-T1 1538 FYCRYCKKGFLNKRSCRRHELRLH 1561 89*****************99987 PP == domain 25 score: 9.7 bits; conditional E-value: 0.0012 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 +C++C+k+F +k++ rrH ++ H FUN_000374-T1 1616 YCRYCKKRFLNKSSCRRHELRLH 1638 6*****************99987 PP == domain 26 score: 0.3 bits; conditional E-value: 1.3 zf-C2H2_4 5 iCgksFsskkaLrrHlkkhH 24 +C+k F k++ rrH +++H FUN_000374-T1 1731 HCRKGFLHKSSCRRHELRVH 1750 8*****************99 PP == domain 27 score: 6.0 bits; conditional E-value: 0.019 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkhH 24 f+C++C+k+F +++ r+H +k H FUN_000374-T1 1804 FCCRYCRKWFFARSSRRKHELKFH 1827 89*************999*99988 PP == domain 28 score: 5.0 bits; conditional E-value: 0.041 zf-C2H2_4 1 fkCpiCgksFsskkaLrrH 19 f C +C+++F + + ++H FUN_000374-T1 1892 FPCQHCSRQFITVSRRYKH 1910 89********999884444 PP >> PRDM2_PR PR domain zinc finger protein 2, PR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 131.7 0.0 8.6e-42 1.6e-38 3 120 .. 140 259 .. 138 262 .. 0.93 Alignments for each domain: == domain 1 score: 131.7 bits; conditional E-value: 8.6e-42 PRDM2_PR 3 lkessieeaglgvfakketipkgtrfGPyeGevvkkee...aannkysweifkegelshfidasdesksNWmryVncarseeeqNLvavqhkgeiY 95 lk ssi++aglg+fak + ++ ++fGPy G+ ++ ++ + +++y+w+i ++g + h+ida+de++sNW+r+Vncar+e+eqNL+a+q++g+iY FUN_000374-T1 140 LKPSSIPDAGLGIFAK-DRFESDVVFGPYWGQKISVSDltpNVDQSYMWDIIENGLVTHVIDARDEKYSNWLRFVNCARNEDEQNLIAFQYRGHIY 234 6889***********7.99*************9998863335589*************************************************** PP PRDM2_PR 96 yrtikdIepgeeLlvwyseeyakrl 120 yr++k Iepg eLlvwy+++ya l FUN_000374-T1 235 YRSFKVIEPGMELLVWYGDRYACDL 259 *********************9766 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.3 0.76 1.4e+03 2 19 .. 274 291 .. 273 293 .. 0.89 2 ? 2.0 7.1 0.28 5.1e+02 2 23 .] 306 327 .. 305 327 .. 0.90 3 ! 13.5 4.6 5.9e-05 0.11 1 23 [] 333 356 .. 333 356 .. 0.96 4 ! 14.0 0.6 4.2e-05 0.077 2 21 .. 363 382 .. 362 383 .. 0.91 5 ! 7.3 0.1 0.0055 10 7 23 .] 394 410 .. 394 410 .. 0.94 6 ! 17.7 3.3 2.8e-06 0.0051 1 23 [] 418 440 .. 418 440 .. 0.98 7 ! 19.5 1.0 7.2e-07 0.0013 2 23 .] 457 478 .. 456 478 .. 0.98 8 ? 5.6 0.3 0.019 34 3 23 .] 487 507 .. 486 507 .. 0.84 9 ! 12.0 0.2 0.00019 0.34 2 23 .] 514 536 .. 513 536 .. 0.94 10 ? 0.3 1.8 0.96 1.7e+03 2 23 .] 591 612 .. 590 612 .. 0.84 11 ! 12.1 4.0 0.00017 0.32 3 23 .] 700 720 .. 698 720 .. 0.96 12 ! 11.9 3.6 0.00019 0.35 1 23 [] 762 784 .. 762 784 .. 0.96 13 ! 11.9 3.6 0.00019 0.35 1 23 [] 832 854 .. 832 854 .. 0.96 14 ! 19.0 1.1 1.1e-06 0.002 1 23 [] 934 956 .. 934 956 .. 0.93 15 ! 10.3 0.2 0.00061 1.1 1 23 [] 988 1011 .. 988 1011 .. 0.98 16 ! 8.8 0.3 0.0018 3.3 1 23 [] 1018 1041 .. 1018 1041 .. 0.92 17 ? 6.0 5.4 0.015 26 1 21 [. 1047 1067 .. 1047 1068 .. 0.94 18 ! 13.0 0.6 8.7e-05 0.16 1 23 [] 1167 1189 .. 1167 1189 .. 0.96 19 ! 18.7 3.5 1.4e-06 0.0025 1 23 [] 1196 1218 .. 1196 1218 .. 0.97 20 ! 8.9 1.5 0.0017 3.1 1 21 [. 1229 1249 .. 1229 1250 .. 0.94 21 ! 11.1 4.6 0.00035 0.64 2 23 .] 1287 1309 .. 1286 1309 .. 0.95 22 ! 10.5 2.4 0.00053 0.97 2 23 .] 1333 1355 .. 1332 1355 .. 0.95 23 ? 4.3 1.1 0.051 92 2 23 .] 1378 1400 .. 1377 1400 .. 0.93 24 ! 7.3 0.5 0.0057 10 2 23 .] 1440 1462 .. 1439 1462 .. 0.92 25 ? -0.3 5.8 1.4 2.6e+03 1 23 [] 1538 1561 .. 1538 1561 .. 0.90 26 ? 1.0 5.6 0.56 1e+03 2 23 .] 1616 1638 .. 1615 1638 .. 0.92 27 ? -2.4 2.7 7 1.3e+04 7 20 .. 1738 1751 .. 1731 1753 .. 0.68 28 ? 3.0 1.8 0.13 2.5e+02 1 20 [. 1892 1911 .. 1892 1915 .. 0.81 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.76 zf-C2H2 2 kCpdCgksFsrksnLkrH 19 +C++C +s + +L +H FUN_000374-T1 274 QCQKCFMICSGPISLASH 291 8*****999999999999 PP == domain 2 score: 2.0 bits; conditional E-value: 0.28 zf-C2H2 2 kCpdCgksFsrksnLkrHlrtH 23 +C +C++sF+++++L H ++H FUN_000374-T1 306 RCIHCDRSFKSQHSLHFHKNIH 327 5779***********9999988 PP == domain 3 score: 13.5 bits; conditional E-value: 5.9e-05 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrt.H 23 ++C +Cgk+F+++ + +rH+ + H FUN_000374-T1 333 FTCRICGKAFTHPASRNRHYHSfH 356 89*****************99888 PP == domain 4 score: 14.0 bits; conditional E-value: 4.2e-05 zf-C2H2 2 kCpdCgksFsrksnLkrHlr 21 +C++Cgk+Fs+ +Lk+H + FUN_000374-T1 363 VCKICGKAFSDDNSLKSHSC 382 7*****************65 PP == domain 5 score: 7.3 bits; conditional E-value: 0.0055 zf-C2H2 7 gksFsrksnLkrHlrtH 23 ++sF ++ L +H+r+H FUN_000374-T1 394 DQSFVSAFALSKHMRVH 410 579*************9 PP == domain 6 score: 17.7 bits; conditional E-value: 2.8e-06 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 y+C+ C k Fs++++L+rH++ H FUN_000374-T1 418 YQCKQCLKFFSSSKSLNRHIKLH 440 9********************99 PP == domain 7 score: 19.5 bits; conditional E-value: 7.2e-07 zf-C2H2 2 kCpdCgksFsrksnLkrHlrtH 23 kC++Cg +Fs++ L +H+r+H FUN_000374-T1 457 KCQHCGNVFSSAVALSNHMRMH 478 8********************9 PP == domain 8 score: 5.6 bits; conditional E-value: 0.019 zf-C2H2 3 CpdCgksFsrksnLkrHlrt.H 23 Cp+C+ s + +L rH+r+ H FUN_000374-T1 487 CPICKVSN-YSGSLARHMRKkH 507 77776655.9**********99 PP == domain 9 score: 12.0 bits; conditional E-value: 0.00019 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 +C +Cgk++ +k L H+ + H FUN_000374-T1 514 RCGKCGKVCADKRVLAVHIAIrH 536 7******************9888 PP == domain 10 score: 0.3 bits; conditional E-value: 0.96 zf-C2H2 2 kCpdCgksFsrksnLkrHlrtH 23 +C++C +F +++ + H+ +H FUN_000374-T1 591 SCEICFAVFPSSKLMHCHRASH 612 6********9999887777766 PP == domain 11 score: 12.1 bits; conditional E-value: 0.00017 zf-C2H2 3 CpdCgksFsrksnLkrHlrtH 23 C++C+ksFs+ ++L++H +H FUN_000374-T1 700 CTICKKSFSTVTSLRSHKASH 720 99***************9998 PP == domain 12 score: 11.9 bits; conditional E-value: 0.00019 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 ++C dC+k+F + +L++H H FUN_000374-T1 762 FRCLDCNKTFPTGRSLRSHKSHH 784 89*****************9988 PP == domain 13 score: 11.9 bits; conditional E-value: 0.00019 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 ++C dC+k+F + +L++H H FUN_000374-T1 832 FRCLDCNKTFPTGRSLRSHKSHH 854 89*****************9988 PP == domain 14 score: 19.0 bits; conditional E-value: 1.1e-06 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 ++C +Cgk+F +k nL rH H FUN_000374-T1 934 FSCGECGKAFISKRNLARHKGHH 956 89*****************8776 PP == domain 15 score: 10.3 bits; conditional E-value: 0.00061 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrt.H 23 y+C+ C +sF s L +H+r+ H FUN_000374-T1 988 YECSTCLESFYGGSALVNHQRRiH 1011 99*******************999 PP == domain 16 score: 8.8 bits; conditional E-value: 0.0018 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrt.H 23 + Cp C+k F ++ +L H + H FUN_000374-T1 1018 FICPFCDKIFLTRASLLLHKQDlH 1041 88*****************98766 PP == domain 17 score: 6.0 bits; conditional E-value: 0.015 zf-C2H2 1 ykCpdCgksFsrksnLkrHlr 21 ++C++C+ +Fs+k++ ++Hl+ FUN_000374-T1 1047 FTCKHCNGRFSSKYSRNNHLC 1067 89*****************86 PP == domain 18 score: 13.0 bits; conditional E-value: 8.7e-05 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 y C++C + F++k L++H r+H FUN_000374-T1 1167 YLCDVCFEPFKTKIGLNNHKRSH 1189 67********************9 PP == domain 19 score: 18.7 bits; conditional E-value: 1.4e-06 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 + C++C++ F +k nL+rH++ H FUN_000374-T1 1196 FICSICHRGFVSKRNLRRHRKLH 1218 88*******************99 PP == domain 20 score: 8.9 bits; conditional E-value: 0.0017 zf-C2H2 1 ykCpdCgksFsrksnLkrHlr 21 + C C k F + s L +H++ FUN_000374-T1 1229 FACFTCSKPFQSYSGLYKHRK 1249 78*****************98 PP == domain 21 score: 11.1 bits; conditional E-value: 0.00035 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 +C++C k F + nL+rH + H FUN_000374-T1 1287 QCQYCEKEFQKRCNLRRHVSKkH 1309 8*****************99988 PP == domain 22 score: 10.5 bits; conditional E-value: 0.00053 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 kC++C + F++ L rH + H FUN_000374-T1 1333 KCQHCERQFRTEFGLLRHVEKrH 1355 8*****************99888 PP == domain 23 score: 4.3 bits; conditional E-value: 0.051 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 C +Cg F++ + ++H + H FUN_000374-T1 1378 NCLYCGNEFNSIHGIRKHVSRkH 1400 5*****************99888 PP == domain 24 score: 7.3 bits; conditional E-value: 0.0057 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 +C++C++ F + s +H + H FUN_000374-T1 1440 RCQYCNRGFPTVSKRYKHVMLvH 1462 7*****************98777 PP == domain 25 score: -0.3 bits; conditional E-value: 1.4 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrt.H 23 ++C +C+k F +k + +rH + H FUN_000374-T1 1538 FYCRYCKKGFLNKRSCRRHELRlH 1561 89********99999999988877 PP == domain 26 score: 1.0 bits; conditional E-value: 0.56 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 +C +C+k+F +ks+ +rH + H FUN_000374-T1 1616 YCRYCKKRFLNKSSCRRHELRlH 1638 6*****************98877 PP == domain 27 score: -2.4 bits; conditional E-value: 7 zf-C2H2 7 gksFsrksnLkrHl 20 +ks +r+++L+ H FUN_000374-T1 1738 HKSSCRRHELRVHK 1751 46667777777775 PP == domain 28 score: 3.0 bits; conditional E-value: 0.13 zf-C2H2 1 ykCpdCgksFsrksnLkrHl 20 + C++C + F + s +H FUN_000374-T1 1892 FPCQHCSRQFITVSRRYKHN 1911 89********9988777775 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 3.5 5.2e-06 0.0095 2 22 .. 305 325 .. 304 325 .. 0.93 2 ? 4.0 0.2 0.045 82 2 23 .. 333 354 .. 332 354 .. 0.92 3 ! 11.9 0.1 0.00015 0.28 4 20 .. 364 380 .. 361 380 .. 0.95 4 ! 7.2 0.9 0.0047 8.6 3 22 .. 419 438 .. 417 438 .. 0.92 5 ? 2.9 0.3 0.1 1.8e+02 4 22 .. 458 476 .. 457 476 .. 0.95 6 ? -3.2 0.0 8.6 1.6e+04 7 21 .. 518 532 .. 515 533 .. 0.89 7 ! 9.1 4.1 0.0011 2.1 4 23 .. 700 719 .. 697 724 .. 0.92 8 ! 10.8 0.0 0.00035 0.63 2 21 .. 762 781 .. 761 782 .. 0.93 9 ! 10.8 0.0 0.00035 0.63 2 21 .. 832 851 .. 831 852 .. 0.93 10 ! 7.4 0.0 0.0039 7 2 21 .. 934 953 .. 933 953 .. 0.93 11 ? -0.6 0.0 1.3 2.3e+03 2 22 .. 988 1008 .. 987 1008 .. 0.90 12 ! 8.4 0.1 0.0019 3.5 2 21 .. 1018 1037 .. 1017 1038 .. 0.91 13 ? 6.0 0.5 0.011 20 2 21 .. 1047 1066 .. 1046 1066 .. 0.93 14 ? 2.1 0.1 0.18 3.3e+02 4 24 .. 1169 1189 .. 1166 1190 .. 0.90 15 ! 10.2 0.0 0.00052 0.94 2 22 .. 1196 1216 .. 1195 1216 .. 0.94 16 ? 2.0 0.6 0.2 3.7e+02 2 13 .. 1229 1240 .. 1228 1247 .. 0.91 17 ? -0.5 5.4 1.2 2.2e+03 4 21 .. 1288 1305 .. 1285 1309 .. 0.82 18 ! 10.0 0.6 0.0006 1.1 2 21 .. 1332 1351 .. 1331 1352 .. 0.89 19 ? 0.6 0.1 0.56 1e+03 2 21 .. 1377 1396 .. 1376 1397 .. 0.86 20 ? 3.0 0.1 0.092 1.7e+02 3 13 .. 1440 1450 .. 1439 1453 .. 0.85 21 ! 7.2 1.8 0.0047 8.5 2 21 .. 1538 1557 .. 1537 1558 .. 0.89 22 ? 3.2 2.4 0.085 1.6e+02 3 21 .. 1616 1634 .. 1614 1635 .. 0.88 23 ? -0.3 2.1 1 1.9e+03 4 11 .. 1806 1813 .. 1803 1823 .. 0.79 24 ! 6.1 0.2 0.01 18 4 13 .. 1894 1903 .. 1892 1906 .. 0.90 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 5.2e-06 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlk 22 + C++Cd+ Fks+++l+ H++ FUN_000374-T1 305 WRCIHCDRSFKSQHSLHFHKN 325 78*****************87 PP == domain 2 score: 4.0 bits; conditional E-value: 0.045 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlkS 23 f C +C K F + +H+ S FUN_000374-T1 333 FTCRICGKAFTHPASRNRHYHS 354 89*****************987 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00015 zf-C2H2_jaz 4 CvlCdKyFksenalqnH 20 C++C K F+++n+l+ H FUN_000374-T1 364 CKICGKAFSDDNSLKSH 380 ****************9 PP == domain 4 score: 7.2 bits; conditional E-value: 0.0047 zf-C2H2_jaz 3 YCvlCdKyFksenalqnHlk 22 C+ C K F+s+++l +H+k FUN_000374-T1 419 QCKQCLKFFSSSKSLNRHIK 438 5*****************98 PP == domain 5 score: 2.9 bits; conditional E-value: 0.1 zf-C2H2_jaz 4 CvlCdKyFksenalqnHlk 22 C++C F+s+ al nH++ FUN_000374-T1 458 CQHCGNVFSSAVALSNHMR 476 *****************96 PP == domain 6 score: -3.2 bits; conditional E-value: 8.6 zf-C2H2_jaz 7 CdKyFksenalqnHl 21 C K + + ++l H+ FUN_000374-T1 518 CGKVCADKRVLAVHI 532 99*********9998 PP == domain 7 score: 9.1 bits; conditional E-value: 0.0011 zf-C2H2_jaz 4 CvlCdKyFksenalqnHlkS 23 C++C+K F++ +l+ H+ S FUN_000374-T1 700 CTICKKSFSTVTSLRSHKAS 719 ******************99 PP == domain 8 score: 10.8 bits; conditional E-value: 0.00035 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 f C C+K+F + ++l+ H+ FUN_000374-T1 762 FRCLDCNKTFPTGRSLRSHK 781 99*****************7 PP == domain 9 score: 10.8 bits; conditional E-value: 0.00035 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 f C C+K+F + ++l+ H+ FUN_000374-T1 832 FRCLDCNKTFPTGRSLRSHK 851 99*****************7 PP == domain 10 score: 7.4 bits; conditional E-value: 0.0039 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 f C +C K F+s ++l +H+ FUN_000374-T1 934 FSCGECGKAFISKRNLARHK 953 88**************9995 PP == domain 11 score: -0.6 bits; conditional E-value: 1.3 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlk 22 ++C C F +al+nH++ FUN_000374-T1 988 YECSTCLESFYGGSALVNHQR 1008 89999*9999999******86 PP == domain 12 score: 8.4 bits; conditional E-value: 0.0019 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 f C+ CdK F + +l H+ FUN_000374-T1 1018 FICPFCDKIFLTRASLLLHK 1037 89**********99999996 PP == domain 13 score: 6.0 bits; conditional E-value: 0.011 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 f C++C+ F+s + nHl FUN_000374-T1 1047 FTCKHCNGRFSSKYSRNNHL 1066 99****************96 PP == domain 14 score: 2.1 bits; conditional E-value: 0.18 zf-C2H2_jaz 4 CvlCdKyFksenalqnHlkSK 24 C +C Fk+ l nH++S+ FUN_000374-T1 1169 CDVCFEPFKTKIGLNNHKRSH 1189 9999999************96 PP == domain 15 score: 10.2 bits; conditional E-value: 0.00052 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlk 22 f C +C + F s ++l++H k FUN_000374-T1 1196 FICSICHRGFVSKRNLRRHRK 1216 99*****************87 PP == domain 16 score: 2.0 bits; conditional E-value: 0.2 zf-C2H2_jaz 2 fYCvlCdKyFks 13 f C C+K F s FUN_000374-T1 1229 FACFTCSKPFQS 1240 89********87 PP == domain 17 score: -0.5 bits; conditional E-value: 1.2 zf-C2H2_jaz 4 CvlCdKyFksenalqnHl 21 C++C K F + +l++H+ FUN_000374-T1 1288 CQYCEKEFQKRCNLRRHV 1305 ********9988888887 PP == domain 18 score: 10.0 bits; conditional E-value: 0.0006 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 + C++C ++F +e l +H+ FUN_000374-T1 1332 WKCQHCERQFRTEFGLLRHV 1351 78***********9999996 PP == domain 19 score: 0.6 bits; conditional E-value: 0.56 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 ++C +C F+s + + H+ FUN_000374-T1 1377 WNCLYCGNEFNSIHGIRKHV 1396 79*********999888886 PP == domain 20 score: 3.0 bits; conditional E-value: 0.092 zf-C2H2_jaz 3 YCvlCdKyFks 13 C++C++ F + FUN_000374-T1 1440 RCQYCNRGFPT 1450 5*******966 PP == domain 21 score: 7.2 bits; conditional E-value: 0.0047 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHl 21 fYC +C+K F + ++ ++H+ FUN_000374-T1 1538 FYCRYCKKGFLNKRSCRRHE 1557 9*********9999888886 PP == domain 22 score: 3.2 bits; conditional E-value: 0.085 zf-C2H2_jaz 3 YCvlCdKyFksenalqnHl 21 YC +C+K F + ++ ++H+ FUN_000374-T1 1616 YCRYCKKRFLNKSSCRRHE 1634 *********9999888886 PP == domain 23 score: -0.3 bits; conditional E-value: 1 zf-C2H2_jaz 4 CvlCdKyF 11 C +C+K+F FUN_000374-T1 1806 CRYCRKWF 1813 99****** PP == domain 24 score: 6.1 bits; conditional E-value: 0.01 zf-C2H2_jaz 4 CvlCdKyFks 13 C++C+++F++ FUN_000374-T1 1894 CQHCSRQFIT 1903 ********98 PP >> zf-C2H2_6 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 3.6 0.13 2.3e+02 3 24 .. 306 327 .. 304 329 .. 0.85 2 ? 1.7 0.4 0.21 3.9e+02 2 11 .. 333 342 .. 333 343 .. 0.91 3 ? 5.0 0.3 0.02 36 3 12 .. 363 372 .. 363 381 .. 0.83 4 ? 0.6 0.1 0.46 8.4e+02 10 27 .] 396 413 .. 394 413 .. 0.87 5 ! 9.9 2.9 0.00059 1.1 2 25 .. 418 441 .. 418 443 .. 0.90 6 ! 15.2 1.6 1.3e-05 0.023 3 27 .] 457 481 .. 457 481 .. 0.95 7 ? -3.0 0.3 6.2 1.1e+04 4 10 .. 487 493 .. 486 494 .. 0.87 8 ? 1.3 2.8 0.29 5.3e+02 4 24 .. 592 612 .. 591 615 .. 0.94 9 ! 29.2 4.5 4.9e-10 8.9e-07 2 25 .. 698 721 .. 697 723 .. 0.94 10 ! 20.1 1.5 3.6e-07 0.00066 2 24 .. 762 784 .. 761 786 .. 0.94 11 ! 20.1 1.5 3.6e-07 0.00066 2 24 .. 832 854 .. 831 856 .. 0.94 12 ? 4.6 2.0 0.027 48 2 26 .. 934 958 .. 933 959 .. 0.91 13 ! 9.7 0.2 0.00064 1.2 2 26 .. 988 1013 .. 987 1014 .. 0.86 14 ? -1.3 0.1 1.9 3.4e+03 2 11 .. 1018 1027 .. 1017 1038 .. 0.83 15 ? 0.2 1.5 0.64 1.2e+03 2 13 .. 1047 1058 .. 1047 1065 .. 0.90 16 ! 8.3 0.1 0.0018 3.2 2 24 .. 1167 1189 .. 1167 1191 .. 0.97 17 ! 13.7 1.6 3.6e-05 0.066 2 26 .. 1196 1220 .. 1196 1221 .. 0.93 18 ! 9.0 3.6 0.0011 2 2 22 .. 1229 1249 .. 1229 1251 .. 0.93 19 ? 3.1 5.0 0.075 1.4e+02 4 24 .. 1288 1309 .. 1287 1312 .. 0.83 20 ? 0.8 1.5 0.4 7.3e+02 3 20 .. 1333 1350 .. 1331 1358 .. 0.76 21 ! 6.4 0.2 0.0074 13 3 24 .. 1378 1400 .. 1377 1403 .. 0.83 22 ? 4.6 0.1 0.025 46 3 13 .. 1440 1450 .. 1440 1451 .. 0.93 23 ? -2.4 2.2 4.3 7.8e+03 2 11 .. 1538 1547 .. 1537 1547 .. 0.87 24 ? -0.9 1.3 1.4 2.5e+03 4 11 .. 1617 1624 .. 1617 1624 .. 0.96 25 ? 1.5 0.3 0.25 4.6e+02 1 11 [. 1891 1901 .. 1891 1903 .. 0.91 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.13 zf-C2H2_6 3 eCsvCgksFssyqaLggHkksH 24 +C C++sF+s+ +L Hk H FUN_000374-T1 306 RCIHCDRSFKSQHSLHFHKNIH 327 6778***********9999555 PP == domain 2 score: 1.7 bits; conditional E-value: 0.21 zf-C2H2_6 2 feCsvCgksF 11 f C +Cgk F FUN_000374-T1 333 FTCRICGKAF 342 78*******9 PP == domain 3 score: 5.0 bits; conditional E-value: 0.02 zf-C2H2_6 3 eCsvCgksFs 12 +C++Cgk Fs FUN_000374-T1 363 VCKICGKAFS 372 5********7 PP == domain 4 score: 0.6 bits; conditional E-value: 0.46 zf-C2H2_6 10 sFssyqaLggHkksHrke 27 sF s aL +H++ H+k+ FUN_000374-T1 396 SFVSAFALSKHMRVHEKQ 413 788888*********985 PP == domain 5 score: 9.9 bits; conditional E-value: 0.00059 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksHr 25 + C++C k Fss ++L+ H k H+ FUN_000374-T1 418 YQCKQCLKFFSSSKSLNRHIKLHE 441 78*****************88776 PP == domain 6 score: 15.2 bits; conditional E-value: 1.3e-05 zf-C2H2_6 3 eCsvCgksFssyqaLggHkksHrke 27 +C+ Cg++Fss aL H++ H+k+ FUN_000374-T1 457 KCQHCGNVFSSAVALSNHMRMHEKQ 481 7*********************985 PP == domain 7 score: -3.0 bits; conditional E-value: 6.2 zf-C2H2_6 4 CsvCgks 10 C++C+ s FUN_000374-T1 487 CPICKVS 493 ****976 PP == domain 8 score: 1.3 bits; conditional E-value: 0.29 zf-C2H2_6 4 CsvCgksFssyqaLggHkksH 24 C +C ++F+s + + H++sH FUN_000374-T1 592 CEICFAVFPSSKLMHCHRASH 612 99*****************99 PP == domain 9 score: 29.2 bits; conditional E-value: 4.9e-10 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksHr 25 f+C++C+ksFs+ ++L+ Hk+sH FUN_000374-T1 698 FCCTICKKSFSTVTSLRSHKASHT 721 9**********************6 PP == domain 10 score: 20.1 bits; conditional E-value: 3.6e-07 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksH 24 f+C C+k+F+++ +L+ Hk +H FUN_000374-T1 762 FRCLDCNKTFPTGRSLRSHKSHH 784 89999*****************9 PP == domain 11 score: 20.1 bits; conditional E-value: 3.6e-07 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksH 24 f+C C+k+F+++ +L+ Hk +H FUN_000374-T1 832 FRCLDCNKTFPTGRSLRSHKSHH 854 89999*****************9 PP == domain 12 score: 4.6 bits; conditional E-value: 0.027 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksHrk 26 f C +Cgk F s +L Hk +H + FUN_000374-T1 934 FSCGECGKAFISKRNLARHKGHHSR 958 77******************99976 PP == domain 13 score: 9.7 bits; conditional E-value: 0.00064 zf-C2H2_6 2 feCsvCgksFssyqaLggHkks.Hrk 26 +eCs+C +sF + aL H ++ H++ FUN_000374-T1 988 YECSTCLESFYGGSALVNHQRRiHKD 1013 9*********9999999998877775 PP == domain 14 score: -1.3 bits; conditional E-value: 1.9 zf-C2H2_6 2 feCsvCgksF 11 f+C+ C+k F FUN_000374-T1 1018 FICPFCDKIF 1027 89*****988 PP == domain 15 score: 0.2 bits; conditional E-value: 0.64 zf-C2H2_6 2 feCsvCgksFss 13 f C+ C+ +Fss FUN_000374-T1 1047 FTCKHCNGRFSS 1058 78********99 PP == domain 16 score: 8.3 bits; conditional E-value: 0.0018 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksH 24 + C+vC + F++ L+ Hk+sH FUN_000374-T1 1167 YLCDVCFEPFKTKIGLNNHKRSH 1189 78********************* PP == domain 17 score: 13.7 bits; conditional E-value: 3.6e-05 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksHrk 26 f+Cs+C++ F s +L+ H+k H + FUN_000374-T1 1196 FICSICHRGFVSKRNLRRHRKLHSS 1220 89*******************9975 PP == domain 18 score: 9.0 bits; conditional E-value: 0.0011 zf-C2H2_6 2 feCsvCgksFssyqaLggHkk 22 f C +C+k F+sy L +H+k FUN_000374-T1 1229 FACFTCSKPFQSYSGLYKHRK 1249 7799****************8 PP == domain 19 score: 3.1 bits; conditional E-value: 0.075 zf-C2H2_6 4 CsvCgksFssyqaLggHk.ksH 24 C++C k+F++ +L+ H k H FUN_000374-T1 1288 CQYCEKEFQKRCNLRRHVsKKH 1309 **********999999985555 PP == domain 20 score: 0.8 bits; conditional E-value: 0.4 zf-C2H2_6 3 eCsvCgksFssyqaLggH 20 +C+ C ++F + L H FUN_000374-T1 1333 KCQHCERQFRTEFGLLRH 1350 8*********98666666 PP == domain 21 score: 6.4 bits; conditional E-value: 0.0074 zf-C2H2_6 3 eCsvCgksFssyqaLggHk.ksH 24 +C +Cg++F+s+ ++H + H FUN_000374-T1 1378 NCLYCGNEFNSIHGIRKHVsRKH 1400 699*********99999973445 PP == domain 22 score: 4.6 bits; conditional E-value: 0.025 zf-C2H2_6 3 eCsvCgksFss 13 +C++C++ F++ FUN_000374-T1 1440 RCQYCNRGFPT 1450 7********98 PP == domain 23 score: -2.4 bits; conditional E-value: 4.3 zf-C2H2_6 2 feCsvCgksF 11 f C +C+k F FUN_000374-T1 1538 FYCRYCKKGF 1547 67******98 PP == domain 24 score: -0.9 bits; conditional E-value: 1.4 zf-C2H2_6 4 CsvCgksF 11 C +C+k+F FUN_000374-T1 1617 CRYCKKRF 1624 99*****9 PP == domain 25 score: 1.5 bits; conditional E-value: 0.25 zf-C2H2_6 1 vfeCsvCgksF 11 +f C+ C+++F FUN_000374-T1 1891 AFPCQHCSRQF 1901 699*******9 PP >> SET SET domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.7 0.0 8.1e-13 1.5e-09 1 105 [] 149 252 .. 149 252 .. 0.85 2 ? -0.5 2.1 1.3 2.3e+03 36 84 .. 349 394 .. 291 407 .. 0.62 3 ? 0.7 0.4 0.55 1e+03 14 71 .. 1017 1088 .. 943 1144 .. 0.75 4 ? -1.8 0.1 3.4 6.2e+03 16 68 .. 1539 1628 .. 1535 1654 .. 0.56 Alignments for each domain: == domain 1 score: 38.7 bits; conditional E-value: 8.1e-13 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxx RF SET 1 GrGlfAtedikkgelileyv.ekllitkeeadkreeeeylft.ldekeaeyvidaraekkgnvarfiNHsc.....epncevevevvngekrivvf 89 G G+fA+++++ + ++++y + i+ + + +++y+ + +++ ++vidar+ek++n+ rf+N c e+n+ + +++ +++i+++ FUN_000374-T1 149 GLGIFAKDRFESDVVFGPYWgQ--KISVSDLTPNVDQSYMWDiIENGLVTHVIDARDEKYSNWLRFVN--CarnedEQNL-IAFQY---RGHIYYR 236 89******************55..6777777777777777775777769999****************..5446667777.88888...******* PP xxxxxxxxxxxxxxxx RF SET 90 alrdIkkgeEltidYg 105 + + I++g El+++Yg FUN_000374-T1 237 SFKVIEPGMELLVWYG 252 ***************8 PP == domain 2 score: -0.5 bits; conditional E-value: 1.3 x..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 36 e..eylftldekeaeyvidaraekkgnvarfiNHscepncevevevvngek 84 + ++ f++d+++ v++ + ++ ++ Hsc++ c + ++ ++ FUN_000374-T1 349 NrhYHSFHVDKES--IVCKICGKAFSDDNSLKSHSCTKTCIQNRQH---GD 394 1445555566553..333333444444556789*******443333...33 PP == domain 3 score: 0.7 bits; conditional E-value: 0.55 xxxxxxxxxxxxxxxxxxxxxxx...................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 14 elileyvekllitkeeadkreee...................eylftldekeaeyvidaraekkgnvarfiNHscep 71 +i+++++k+++t++ ++++ + ++++ +++++ + + + n+ +f N c+ FUN_000374-T1 1017 NFICPFCDKIFLTRASLLLHKQDlhsssdpftckhcngrfssK----YSRN-NHLCLSEGSPCLANEVSFSNNQCSR 1088 5889999888888888888888888887777777777643331....2222.4556666666666666666655533 PP == domain 4 score: -1.8 bits; conditional E-value: 3.4 xxxxxxxxxxxxxxxxxxxxx................xxxxxxxxxx.............................xxxxxxxxxxxxxxxxxx RF SET 16 ileyvekllitkeeadkreee................eylftldeke.............................aeyvidaraekkgnvarf 64 ++y++k +++k+ ++++e + + e ++ ++d ++ ++ + rf FUN_000374-T1 1539 YCRYCKKGFLNKRSCRRHELRlhekklksastvsqdsK--------EaagnkakttgqhfsevkcksltglskaitKRSALDFNSYCRYCKKRF 1624 57777667777777777777766655544433333330........033333444444444444444445444444444455445555555588 PP xxxx RF SET 65 iNHs 68 +N s FUN_000374-T1 1625 LNKS 1628 8866 PP >> zf-C2H2_11 zinc-finger C2H2-type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.4 0.77 1.4e+03 5 23 .. 273 291 .. 271 293 .. 0.75 2 ? 3.4 5.4 0.046 84 6 26 .. 306 326 .. 304 328 .. 0.90 3 ? 4.5 1.4 0.021 38 6 24 .. 334 352 .. 332 356 .. 0.88 4 ? 2.7 0.4 0.08 1.5e+02 2 23 .. 359 380 .. 358 382 .. 0.87 5 ? 0.9 0.2 0.29 5.3e+02 14 26 .. 397 409 .. 395 412 .. 0.87 6 ! 15.8 1.2 6.4e-06 0.012 5 24 .. 418 437 .. 415 440 .. 0.91 7 ! 20.4 0.4 2.3e-07 0.00042 5 25 .. 456 476 .. 454 480 .. 0.92 8 ? 2.2 0.2 0.11 2.1e+02 17 25 .. 496 504 .. 486 507 .. 0.76 9 ? -3.3 0.8 5.9 1.1e+04 6 12 .. 514 520 .. 513 536 .. 0.72 10 ? -2.0 3.9 2.3 4.1e+03 3 23 .. 696 716 .. 695 718 .. 0.88 11 ? 3.5 0.4 0.045 82 3 23 .. 760 780 .. 759 781 .. 0.78 12 ? 3.2 0.3 0.055 1e+02 3 23 .. 830 850 .. 829 851 .. 0.79 13 ? 4.5 0.3 0.022 40 7 23 .. 936 952 .. 933 953 .. 0.94 14 ? 1.3 2.0 0.22 4e+02 6 24 .. 1048 1066 .. 1044 1068 .. 0.87 15 ? 1.3 3.9 0.21 3.9e+02 7 25 .. 1198 1216 .. 1196 1218 .. 0.92 16 ? 1.2 1.2 0.23 4.2e+02 5 24 .. 1286 1305 .. 1283 1309 .. 0.90 17 ? 4.8 0.7 0.017 32 5 24 .. 1332 1351 .. 1328 1355 .. 0.89 18 ? 0.0 0.0 0.54 9.8e+02 6 17 .. 1378 1389 .. 1373 1397 .. 0.75 19 ? -2.3 0.3 2.9 5.3e+03 5 15 .. 1439 1449 .. 1438 1463 .. 0.59 20 ? -2.7 0.5 3.8 6.9e+03 5 14 .. 1892 1901 .. 1890 1901 .. 0.79 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.77 zf-C2H2_11 5 cqCllCGlCftSqisLsRH 23 qC++C + + +isL H FUN_000374-T1 273 IQCQKCFMICSGPISLASH 291 5999997777777777655 PP == domain 2 score: 3.4 bits; conditional E-value: 0.046 zf-C2H2_11 6 qCllCGlCftSqisLsRHlfI 26 +C +C + f Sq sL H I FUN_000374-T1 306 RCIHCDRSFKSQHSLHFHKNI 326 8**************999876 PP == domain 3 score: 4.5 bits; conditional E-value: 0.021 zf-C2H2_11 6 qCllCGlCftSqisLsRHl 24 C+ CG ft + s +RH FUN_000374-T1 334 TCRICGKAFTHPASRNRHY 352 5*****************7 PP == domain 4 score: 2.7 bits; conditional E-value: 0.08 zf-C2H2_11 2 estcqCllCGlCftSqisLsRH 23 + + C CG f+ + sL+ H FUN_000374-T1 359 KESIVCKICGKAFSDDNSLKSH 380 56778**************988 PP == domain 5 score: 0.9 bits; conditional E-value: 0.29 zf-C2H2_11 14 ftSqisLsRHlfI 26 f S+ +Ls H+++ FUN_000374-T1 397 FVSAFALSKHMRV 409 889********95 PP == domain 6 score: 15.8 bits; conditional E-value: 6.4e-06 zf-C2H2_11 5 cqCllCGlCftSqisLsRHl 24 +qC +C f+S+ sL+RH+ FUN_000374-T1 418 YQCKQCLKFFSSSKSLNRHI 437 8******************7 PP == domain 7 score: 20.4 bits; conditional E-value: 2.3e-07 zf-C2H2_11 5 cqCllCGlCftSqisLsRHlf 25 ++C++CG f+S+++Ls H++ FUN_000374-T1 456 QKCQHCGNVFSSAVALSNHMR 476 79******************8 PP == domain 8 score: 2.2 bits; conditional E-value: 0.11 zf-C2H2_11 17 qisLsRHlf 25 ++sL RH++ FUN_000374-T1 496 SGSLARHMR 504 59******8 PP == domain 9 score: -3.3 bits; conditional E-value: 5.9 zf-C2H2_11 6 qCllCGl 12 +C +CG FUN_000374-T1 514 RCGKCGK 520 7999985 PP == domain 10 score: -2.0 bits; conditional E-value: 2.3 zf-C2H2_11 3 stcqCllCGlCftSqisLsRH 23 +++ C C+ f+ sL+ H FUN_000374-T1 696 GSFCCTICKKSFSTVTSLRSH 716 5778**************988 PP == domain 11 score: 3.5 bits; conditional E-value: 0.045 zf-C2H2_11 3 stcqCllCGlCftSqisLsRH 23 +t++Cl+C f sL+ H FUN_000374-T1 760 ATFRCLDCNKTFPTGRSLRSH 780 79******9888777776655 PP == domain 12 score: 3.2 bits; conditional E-value: 0.055 zf-C2H2_11 3 stcqCllCGlCftSqisLsRH 23 +t++Cl+C f sL+ H FUN_000374-T1 830 ATFRCLDCNKTFPTGRSLRSH 850 79******9888777776655 PP == domain 13 score: 4.5 bits; conditional E-value: 0.022 zf-C2H2_11 7 CllCGlCftSqisLsRH 23 C +CG f S+ L RH FUN_000374-T1 936 CGECGKAFISKRNLARH 952 99*************** PP == domain 14 score: 1.3 bits; conditional E-value: 0.22 zf-C2H2_11 6 qCllCGlCftSqisLsRHl 24 C +C f+S+ s + Hl FUN_000374-T1 1048 TCKHCNGRFSSKYSRNNHL 1066 5***********9987776 PP == domain 15 score: 1.3 bits; conditional E-value: 0.21 zf-C2H2_11 7 CllCGlCftSqisLsRHlf 25 C C + f S+ L+RH+ FUN_000374-T1 1198 CSICHRGFVSKRNLRRHRK 1216 999**************95 PP == domain 16 score: 1.2 bits; conditional E-value: 0.23 zf-C2H2_11 5 cqCllCGlCftSqisLsRHl 24 qC+ C f L+RH FUN_000374-T1 1286 WQCQYCEKEFQKRCNLRRHV 1305 59*****************6 PP == domain 17 score: 4.8 bits; conditional E-value: 0.017 zf-C2H2_11 5 cqCllCGlCftSqisLsRHl 24 +C++C + f + L RH FUN_000374-T1 1332 WKCQHCERQFRTEFGLLRHV 1351 59*****************6 PP == domain 18 score: 0.0 bits; conditional E-value: 0.54 zf-C2H2_11 6 qCllCGlCftSq 17 Cl CG f S FUN_000374-T1 1378 NCLYCGNEFNSI 1389 6*****999885 PP == domain 19 score: -2.3 bits; conditional E-value: 2.9 zf-C2H2_11 5 cqCllCGlCft 15 +C+ C + f FUN_000374-T1 1439 IRCQYCNRGFP 1449 68888887774 PP == domain 20 score: -2.7 bits; conditional E-value: 3.8 zf-C2H2_11 5 cqCllCGlCf 14 + C++C + f FUN_000374-T1 1892 FPCQHCSRQF 1901 56****8876 PP >> zf-H2C2_2 Zinc-finger double domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.1 0.0044 8 12 26 .] 302 316 .. 298 316 .. 0.88 2 ! 17.4 2.8 3.3e-06 0.006 4 26 .] 322 344 .. 319 344 .. 0.92 3 ! 9.0 1.0 0.0015 2.7 3 25 .. 349 372 .. 347 373 .. 0.88 4 ! 16.5 1.3 6e-06 0.011 1 24 [. 402 427 .. 402 429 .. 0.83 5 ? 1.5 1.2 0.36 6.5e+02 2 25 .. 433 466 .. 432 467 .. 0.55 6 ! 8.1 0.2 0.003 5.4 1 21 [. 470 491 .. 470 493 .. 0.86 7 ! 16.6 0.6 5.9e-06 0.011 1 24 [. 498 522 .. 498 524 .. 0.92 8 ? 2.5 2.1 0.18 3.3e+02 13 26 .] 696 709 .. 693 709 .. 0.84 9 ? 0.2 0.8 0.92 1.7e+03 2 10 .. 713 721 .. 712 728 .. 0.75 10 ? 0.2 0.1 0.95 1.7e+03 14 24 .. 761 771 .. 757 771 .. 0.87 11 ? -0.1 0.1 1.2 2.2e+03 15 24 .. 832 841 .. 827 841 .. 0.89 12 ? 5.8 0.2 0.015 28 11 25 .. 929 944 .. 925 945 .. 0.81 13 ? -2.9 2.1 8.9 1.6e+04 1 12 [. 948 959 .. 948 963 .. 0.80 14 ? 4.9 0.1 0.031 57 11 24 .. 984 997 .. 980 998 .. 0.89 15 ! 9.5 0.1 0.001 1.8 1 25 [. 1002 1028 .. 1002 1029 .. 0.81 16 ! 10.4 0.8 0.00052 0.95 5 26 .] 1036 1058 .. 1034 1058 .. 0.92 17 ? -1.4 0.4 3 5.5e+03 13 20 .. 1165 1172 .. 1162 1177 .. 0.87 18 ! 11.7 0.2 0.0002 0.37 2 26 .] 1182 1207 .. 1181 1207 .. 0.89 19 ! 8.6 0.5 0.002 3.6 1 22 [. 1210 1236 .. 1210 1239 .. 0.93 20 ? 5.0 0.1 0.029 53 10 24 .. 1281 1295 .. 1269 1296 .. 0.86 21 ? -1.1 5.8 2.4 4.4e+03 12 25 .. 1329 1342 .. 1300 1343 .. 0.75 22 ? 2.1 0.1 0.23 4.2e+02 12 25 .. 1374 1387 .. 1372 1388 .. 0.85 23 ? 0.8 1.5 0.63 1.1e+03 15 25 .. 1538 1548 .. 1535 1549 .. 0.87 24 ? 0.2 0.8 0.92 1.7e+03 17 25 .. 1617 1625 .. 1616 1626 .. 0.88 25 ? -1.5 0.3 3.3 6e+03 2 12 .. 1742 1752 .. 1741 1755 .. 0.72 26 ? -0.9 4.5 2 3.7e+03 14 24 .. 1803 1813 .. 1801 1814 .. 0.89 27 ? 2.7 0.5 0.15 2.8e+02 14 25 .. 1890 1902 .. 1886 1903 .. 0.80 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0044 zf-H2C2_2 12 ekpykCpeCgksFks 26 +++++C++C+ sFks FUN_000374-T1 302 HDRWRCIHCDRSFKS 316 5789*********96 PP == domain 2 score: 17.4 bits; conditional E-value: 3.3e-06 zf-H2C2_2 4 rHmrtHtgekpykCpeCgksFks 26 H+ +H g +p+ C Cgk+F++ FUN_000374-T1 322 FHKNIHKGLRPFTCRICGKAFTH 344 6********************85 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0015 zf-H2C2_2 3 krHmrtHtgekp.ykCpeCgksFk 25 +rH + +++k+ C+ Cgk+F+ FUN_000374-T1 349 NRHYHSFHVDKEsIVCKICGKAFS 372 79****8888888**********7 PP == domain 4 score: 16.5 bits; conditional E-value: 6e-06 zf-H2C2_2 1 aLkrHmrtHtgek..pykCpeCgksF 24 aL +Hmr H +++ py+C++C k F FUN_000374-T1 402 ALSKHMRVHEKQRdtPYQCKQCLKFF 427 6899******887457******9866 PP == domain 5 score: 1.5 bits; conditional E-value: 0.36 zf-H2C2_2 2 LkrHmrtHt.......gekpy......kCpeCgksFk 25 L+rH++ H + kC +Cg F+ FUN_000374-T1 433 LNRHIKLHEtshtarsQ---KkapagqKCQHCGNVFS 466 66676666333334430...14455669999998776 PP == domain 6 score: 8.1 bits; conditional E-value: 0.003 zf-H2C2_2 1 aLkrHmrtHtgekp.ykCpeCg 21 aL Hmr+H ++++ Cp C FUN_000374-T1 470 ALSNHMRMHEKQFRiNACPICK 491 5899******9988679**996 PP == domain 7 score: 16.6 bits; conditional E-value: 5.9e-06 zf-H2C2_2 1 aLkrHmrt.HtgekpykCpeCgksF 24 +L rHmr+ H g k +C +Cgk FUN_000374-T1 498 SLARHMRKkHPGAKVIRCGKCGKVC 522 599****99*************975 PP == domain 8 score: 2.5 bits; conditional E-value: 0.18 zf-H2C2_2 13 kpykCpeCgksFks 26 + C C ksF++ FUN_000374-T1 696 GSFCCTICKKSFST 709 569*********86 PP == domain 9 score: 0.2 bits; conditional E-value: 0.92 zf-H2C2_2 2 LkrHmrtHt 10 L++H+++Ht FUN_000374-T1 713 LRSHKASHT 721 788888887 PP == domain 10 score: 0.2 bits; conditional E-value: 0.95 zf-H2C2_2 14 pykCpeCgksF 24 ++C C k+F FUN_000374-T1 761 TFRCLDCNKTF 771 59*******99 PP == domain 11 score: -0.1 bits; conditional E-value: 1.2 zf-H2C2_2 15 ykCpeCgksF 24 ++C C k+F FUN_000374-T1 832 FRCLDCNKTF 841 9*******99 PP == domain 12 score: 5.8 bits; conditional E-value: 0.015 zf-H2C2_2 11 gekp.ykCpeCgksFk 25 +++ + C eCgk+F FUN_000374-T1 929 SKRElFSCGECGKAFI 944 566779*********6 PP == domain 13 score: -2.9 bits; conditional E-value: 8.9 zf-H2C2_2 1 aLkrHmrtHtge 12 +L rH+ +H+ FUN_000374-T1 948 NLARHKGHHSRS 959 799****99865 PP == domain 14 score: 4.9 bits; conditional E-value: 0.031 zf-H2C2_2 11 gekpykCpeCgksF 24 ++k y+C C +sF FUN_000374-T1 984 NQKTYECSTCLESF 997 6899*********9 PP == domain 15 score: 9.5 bits; conditional E-value: 0.001 zf-H2C2_2 1 aLkrHmrt.Ht.gekpykCpeCgksFk 25 aL H+r+ H +++ Cp+C+k F FUN_000374-T1 1002 ALVNHQRRiHKdANSNFICPFCDKIFL 1028 5889***989944455********996 PP == domain 16 score: 10.4 bits; conditional E-value: 0.00052 zf-H2C2_2 5 Hmrt.HtgekpykCpeCgksFks 26 H+ H+ +p+ C++C +F+s FUN_000374-T1 1036 HKQDlHSSSDPFTCKHCNGRFSS 1058 88888****************85 PP == domain 17 score: -1.4 bits; conditional E-value: 3 zf-H2C2_2 13 kpykCpeC 20 py C++C FUN_000374-T1 1165 EPYLCDVC 1172 69*****9 PP == domain 18 score: 11.7 bits; conditional E-value: 0.0002 zf-H2C2_2 2 LkrHmrtHtgekp.ykCpeCgksFks 26 L+ H+r+H g ++ + C C+ F+s FUN_000374-T1 1182 LNNHKRSHIGRSEpFICSICHRGFVS 1207 899********755*********985 PP == domain 19 score: 8.6 bits; conditional E-value: 0.002 zf-H2C2_2 1 aLkrHmrtHt.....gekpykCpeCgk 22 +L+rH + H+ + +p+ C C+k FUN_000374-T1 1210 NLRRHRKLHSsspevKVFPFACFTCSK 1236 7************99999*******98 PP == domain 20 score: 5.0 bits; conditional E-value: 0.029 zf-H2C2_2 10 tgekpykCpeCgksF 24 t e +++C +C+k F FUN_000374-T1 1281 TSEGKWQCQYCEKEF 1295 46778********98 PP == domain 21 score: -1.1 bits; conditional E-value: 2.4 zf-H2C2_2 12 ekpykCpeCgksFk 25 e+++kC +C+ +F FUN_000374-T1 1329 ETHWKCQHCERQFR 1342 5679*******996 PP == domain 22 score: 2.1 bits; conditional E-value: 0.23 zf-H2C2_2 12 ekpykCpeCgksFk 25 ++p+ C +Cg F+ FUN_000374-T1 1374 KNPWNCLYCGNEFN 1387 789*******8887 PP == domain 23 score: 0.8 bits; conditional E-value: 0.63 zf-H2C2_2 15 ykCpeCgksFk 25 + C +C k F FUN_000374-T1 1538 FYCRYCKKGFL 1548 89*******96 PP == domain 24 score: 0.2 bits; conditional E-value: 0.92 zf-H2C2_2 17 CpeCgksFk 25 C +C k+F FUN_000374-T1 1617 CRYCKKRFL 1625 ********6 PP == domain 25 score: -1.5 bits; conditional E-value: 3.3 zf-H2C2_2 2 LkrHmrtHtge 12 +rH+ + +++ FUN_000374-T1 1742 CRRHELRVHKK 1752 69***995543 PP == domain 26 score: -0.9 bits; conditional E-value: 2 zf-H2C2_2 14 pykCpeCgksF 24 ++ C +C+k+F FUN_000374-T1 1803 NFCCRYCRKWF 1813 599*******9 PP == domain 27 score: 2.7 bits; conditional E-value: 0.15 zf-H2C2_2 14 p.ykCpeCgksFk 25 + ++C +C+ +F FUN_000374-T1 1890 KaFPCQHCSRQFI 1902 349********96 PP >> zf-C2H2_7th_ZNF462 Zinc finger protein 462, seventh C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.1 2.9 5.2e+03 3 11 .. 331 339 .. 329 340 .. 0.86 2 ? 0.7 0.4 0.33 6e+02 2 10 .. 415 423 .. 414 440 .. 0.74 3 ? 5.0 1.9 0.016 29 6 27 .. 457 478 .. 456 491 .. 0.85 4 ! 6.6 0.5 0.0047 8.6 7 33 .. 487 512 .. 482 513 .. 0.82 5 ? -2.1 0.2 2.6 4.7e+03 4 23 .. 761 780 .. 759 783 .. 0.88 6 ? -2.4 0.1 3.2 5.8e+03 5 23 .. 832 850 .. 830 853 .. 0.89 7 ? -2.7 0.3 3.9 7.1e+03 2 11 .. 985 994 .. 984 1011 .. 0.61 8 ? 1.6 0.2 0.17 3.2e+02 1 11 [. 1043 1053 .. 1043 1057 .. 0.87 9 ? -1.9 0.2 2.2 4e+03 1 10 [. 1163 1172 .. 1163 1173 .. 0.88 10 ? -2.8 0.1 4 7.4e+03 2 23 .. 1193 1214 .. 1192 1217 .. 0.73 11 ? -2.3 1.5 3 5.5e+03 6 28 .. 1287 1309 .. 1284 1310 .. 0.79 12 ! 6.4 0.5 0.0057 10 2 28 .. 1329 1355 .. 1328 1357 .. 0.91 13 ! 17.8 0.4 1.6e-06 0.0029 3 32 .. 1375 1404 .. 1373 1405 .. 0.93 14 ? -1.9 0.4 2.2 4.1e+03 10 24 .. 1441 1455 .. 1440 1457 .. 0.75 15 ? 0.1 0.2 0.5 9.2e+02 3 11 .. 1890 1898 .. 1888 1917 .. 0.85 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 2.9 zf-C2H2_7th_ZNF462 3 lvYkCkhCs 11 +++ C+ C+ FUN_000374-T1 331 RPFTCRICG 339 79******6 PP == domain 2 score: 0.7 bits; conditional E-value: 0.33 zf-C2H2_7th_ZNF462 2 slvYkCkhC 10 +++Y+Ck C FUN_000374-T1 415 DTPYQCKQC 423 799****** PP == domain 3 score: 5.0 bits; conditional E-value: 0.016 zf-C2H2_7th_ZNF462 6 kCkhCsYtnpnvrgvltHyqkk 27 kC+hC+ + ++ ++++H+ + FUN_000374-T1 457 KCQHCGNVFSSAVALSNHMRMH 478 8*****************9986 PP == domain 4 score: 6.6 bits; conditional E-value: 0.0047 zf-C2H2_7th_ZNF462 7 CkhCsYtnpnvrgvltHyqkkHPtvkv 33 C C+ ++++ ++ H+ kkHP+ kv FUN_000374-T1 487 CPICK-VSNYSGSLARHMRKKHPGAKV 512 55555.67888899**********997 PP == domain 5 score: -2.1 bits; conditional E-value: 2.6 zf-C2H2_7th_ZNF462 4 vYkCkhCsYtnpnvrgvltH 23 ++C C t p+ r++ H FUN_000374-T1 761 TFRCLDCNKTFPTGRSLRSH 780 59******999999999988 PP == domain 6 score: -2.4 bits; conditional E-value: 3.2 zf-C2H2_7th_ZNF462 5 YkCkhCsYtnpnvrgvltH 23 ++C C t p+ r++ H FUN_000374-T1 832 FRCLDCNKTFPTGRSLRSH 850 99*****999999999988 PP == domain 7 score: -2.7 bits; conditional E-value: 3.9 zf-C2H2_7th_ZNF462 2 slvYkCkhCs 11 ++ Y C+ C FUN_000374-T1 985 QKTYECSTCL 994 5789999995 PP == domain 8 score: 1.6 bits; conditional E-value: 0.17 zf-C2H2_7th_ZNF462 1 sslvYkCkhCs 11 ss ++ CkhC FUN_000374-T1 1043 SSDPFTCKHCN 1053 5789******6 PP == domain 9 score: -1.9 bits; conditional E-value: 2.2 zf-C2H2_7th_ZNF462 1 sslvYkCkhC 10 s+ +Y C +C FUN_000374-T1 1163 SDEPYLCDVC 1172 5789****** PP == domain 10 score: -2.8 bits; conditional E-value: 4 zf-C2H2_7th_ZNF462 2 slvYkCkhCsYtnpnvrgvltH 23 s ++ C+ C ++ r++ H FUN_000374-T1 1193 SEPFICSICHRGFVSKRNLRRH 1214 67899****8766666666666 PP == domain 11 score: -2.3 bits; conditional E-value: 3 zf-C2H2_7th_ZNF462 6 kCkhCsYtnpnvrgvltHyqkkH 28 +C+ C+ + + ++ H kkH FUN_000374-T1 1287 QCQYCEKEFQKRCNLRRHVSKKH 1309 78888877777778888888888 PP == domain 12 score: 6.4 bits; conditional E-value: 0.0057 zf-C2H2_7th_ZNF462 2 slvYkCkhCsYtnpnvrgvltHyqkkH 28 ++ +kC+hC+ + g+l H k+H FUN_000374-T1 1329 ETHWKCQHCERQFRTEFGLLRHVEKRH 1355 5678**********************9 PP == domain 13 score: 17.8 bits; conditional E-value: 1.6e-06 zf-C2H2_7th_ZNF462 3 lvYkCkhCsYtnpnvrgvltHyqkkHPtvk 32 ++ C C+ + ++++g+ +H +kHP++k FUN_000374-T1 1375 NPWNCLYCGNEFNSIHGIRKHVSRKHPGRK 1404 5789************************99 PP == domain 14 score: -1.9 bits; conditional E-value: 2.2 zf-C2H2_7th_ZNF462 10 CsYtnpnvrgvltHy 24 C+Y+n + v++ y FUN_000374-T1 1441 CQYCNRGFPTVSKRY 1455 999998877777655 PP == domain 15 score: 0.1 bits; conditional E-value: 0.5 zf-C2H2_7th_ZNF462 3 lvYkCkhCs 11 + + C+hCs FUN_000374-T1 1890 KAFPCQHCS 1898 6789****8 PP >> DddA-like Double-stranded DNA deaminase toxin A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.0 0.0019 3.5 21 61 .. 778 818 .. 764 831 .. 0.81 2 ! 5.6 0.1 0.0099 18 21 64 .. 848 891 .. 833 904 .. 0.77 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0019 DddA-like 21 ddgkktrGqlfrkdgrpisaeliSgrgepadrankllaelg 61 ++k ++G+lf++ p++++l S++ ++ d++n ++e FUN_000374-T1 778 RSHKSHHGRLFTSGRLPLNPMLKSSQPSEEDSRNPSVEECD 818 589**********9999********9999999998888776 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0099 DddA-like 21 ddgkktrGqlfrkdgrpisaeliSgrgepadrankllaelgaks 64 ++k ++G+lf++ p+++ l S++ ++ d++ l+e + + FUN_000374-T1 848 RSHKSHHGRLFTSGRFPLNPLLKSSQPSEEDSRDTSLEECDSSK 891 589**********9999********8888888888888777333 PP >> TSTD2_N TSTD2 protein N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 6.8 0.18 3.3e+02 25 49 .. 297 323 .. 288 328 .. 0.84 2 ? -2.6 4.1 3.9 7.2e+03 13 52 .. 399 439 .. 389 475 .. 0.78 3 ? -3.6 0.4 8.4 1.5e+04 28 49 .. 929 952 .. 912 957 .. 0.68 4 ? 14.8 3.9 1.4e-05 0.026 26 63 .. 1279 1318 .. 1271 1321 .. 0.86 5 ? 12.9 1.4 5.5e-05 0.1 21 56 .. 1320 1357 .. 1315 1370 .. 0.87 6 ? 16.0 0.1 6.1e-06 0.011 24 55 .. 1368 1401 .. 1358 1407 .. 0.85 7 ? 0.2 0.0 0.53 9.7e+02 36 58 .. 1444 1466 .. 1423 1469 .. 0.88 8 ? -2.3 0.2 3.1 5.7e+03 36 60 .. 1543 1567 .. 1538 1573 .. 0.87 9 ? 0.7 0.2 0.38 6.9e+02 35 64 .. 1619 1648 .. 1601 1654 .. 0.81 10 ? 2.9 0.6 0.074 1.3e+02 36 63 .. 1732 1759 .. 1720 1766 .. 0.91 11 ? -3.3 0.2 6.4 1.2e+04 36 64 .. 1809 1837 .. 1798 1841 .. 0.77 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.18 TSTD2_N 25 seeskeksWkC..CgqtFkelssIHkH 49 +++s++ +W+C C++ Fk++ s H H FUN_000374-T1 297 QMNSEHDRWRCihCDRSFKSQHSLHFH 323 4567899*****************988 PP == domain 2 score: -2.6 bits; conditional E-value: 3.9 TSTD2_N 13 alfVkskevpaaseeskeksWkC..CgqtFkelssIHkHvAa 52 ++f sk++ ++ +++++ +C C + F+++ s +H+ FUN_000374-T1 399 SAFALSKHMRVHE-KQRDTPYQCkqCLKFFSSSKSLNRHIKL 439 4566677776654.3456666776699************954 PP == domain 3 score: -3.6 bits; conditional E-value: 8.4 TSTD2_N 28 skeksWkC..CgqtFkelssIHkH 49 sk++ +C Cg++F ++ + +H FUN_000374-T1 929 SKRELFSCgeCGKAFISKRNLARH 952 345566777799999999999888 PP == domain 4 score: 14.8 bits; conditional E-value: 1.4e-05 TSTD2_N 26 eeskeksWkC..CgqtFkelssIHkHvAaqHaaeikqqte 63 ++++e +W+C C+++F+++ + +Hv+++Ha++ k qt+ FUN_000374-T1 1279 MKTSEGKWQCqyCEKEFQKRCNLRRHVSKKHAKQPKLQTQ 1318 4567889*************************98777776 PP == domain 5 score: 12.9 bits; conditional E-value: 5.5e-05 TSTD2_N 21 vpaaseeskeksWkC..CgqtFkelssIHkHvAaqHaa 56 p++ ++s+e++WkC C+++F+ + + +Hv ++H++ FUN_000374-T1 1320 FPSPGMKSTETHWKCqhCERQFRTEFGLLRHVEKRHDK 1357 5677788999**************************97 PP == domain 6 score: 16.0 bits; conditional E-value: 6.1e-06 TSTD2_N 24 aseeskeksWkC..CgqtFkelssIHkHvAaqHa 55 ++ +++++ W+C Cg++F++ +I kHv+++H FUN_000374-T1 1368 KTLRDNKNPWNClyCGNEFNSIHGIRKHVSRKHP 1401 456678999************************5 PP == domain 7 score: 0.2 bits; conditional E-value: 0.53 TSTD2_N 36 CgqtFkelssIHkHvAaqHaaei 58 C++ F s+ kHv H++e FUN_000374-T1 1444 CNRGFPTVSKRYKHVMLVHKEEL 1466 99999999************996 PP == domain 8 score: -2.3 bits; conditional E-value: 3.1 TSTD2_N 36 CgqtFkelssIHkHvAaqHaaeikq 60 C++ F ++ s +H + H+++ k+ FUN_000374-T1 1543 CKKGFLNKRSCRRHELRLHEKKLKS 1567 9*************99999998765 PP == domain 9 score: 0.7 bits; conditional E-value: 0.38 TSTD2_N 35 CCgqtFkelssIHkHvAaqHaaeikqqtea 64 C++ F ++ss +H + H++ k+ +a FUN_000374-T1 1619 YCKKRFLNKSSCRRHELRLHEKRLKSSSAA 1648 5*******************9998877666 PP == domain 10 score: 2.9 bits; conditional E-value: 0.074 TSTD2_N 36 CgqtFkelssIHkHvAaqHaaeikqqte 63 C++ F +ss +H + H++eik+ + FUN_000374-T1 1732 CRKGFLHKSSCRRHELRVHKKEIKSSSA 1759 9**********************98765 PP == domain 11 score: -3.3 bits; conditional E-value: 6.4 TSTD2_N 36 CgqtFkelssIHkHvAaqHaaeikqqtea 64 C++ F +ss kH + Ha++ ++ ++ FUN_000374-T1 1809 CRKWFFARSSRRKHELKFHANQLESSSAS 1837 88889999999999888888888777665 PP >> zf-Di19 Drought induced 19 protein (Di19), zinc-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 4.3 0.016 29 3 44 .. 333 374 .. 331 382 .. 0.79 2 ? -1.9 0.4 3.2 5.8e+03 16 52 .. 402 440 .. 398 442 .. 0.71 3 ? 16.0 2.2 8e-06 0.015 4 53 .. 457 507 .. 455 508 .. 0.82 4 ? 1.4 0.0 0.29 5.3e+02 4 31 .. 514 542 .. 511 544 .. 0.82 5 ? 2.7 0.8 0.12 2.2e+02 2 28 .. 697 723 .. 696 728 .. 0.74 6 ? -1.2 0.2 2 3.6e+03 3 20 .. 934 952 .. 910 962 .. 0.58 7 ? 13.6 0.9 4.7e-05 0.086 2 39 .. 987 1025 .. 986 1026 .. 0.90 8 ? 15.2 2.4 1.5e-05 0.027 2 42 .. 1017 1057 .. 1016 1070 .. 0.79 9 ? 10.8 0.9 0.00036 0.65 3 48 .. 1167 1214 .. 1165 1220 .. 0.73 10 ? 9.0 0.5 0.0012 2.3 3 30 .. 1286 1314 .. 1284 1317 .. 0.84 11 ? 4.4 0.3 0.035 63 3 27 .. 1332 1357 .. 1330 1361 .. 0.82 12 ? 6.0 0.2 0.011 20 4 30 .. 1378 1405 .. 1375 1426 .. 0.86 13 ? -0.4 0.1 1.1 2e+03 4 28 .. 1440 1465 .. 1438 1468 .. 0.78 14 ? 1.1 0.4 0.38 7e+02 2 18 .. 1537 1553 .. 1536 1568 .. 0.68 15 ? -2.5 0.3 4.9 8.9e+03 5 18 .. 1617 1630 .. 1615 1644 .. 0.70 16 ? -2.5 0.5 4.9 8.9e+03 2 20 .. 1803 1822 .. 1802 1833 .. 0.68 17 ? -1.6 0.2 2.6 4.7e+03 2 15 .. 1891 1905 .. 1890 1918 .. 0.69 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.016 zf-Di19 3 ftCPyCgeefdvvsLceHvedeHrveskevvCPvCaekvtkd 44 ftC Cg+ f+ + + +v++++ vC +C + ++d FUN_000374-T1 333 FTCRICGKAFTHPASRNRHYHSFHVDKESIVCKICGKAFSDD 374 9*******988876665555556678999******9988765 PP == domain 2 score: -1.9 bits; conditional E-value: 3.2 zf-Di19 16 sLceHvedeHrveskevvCPvCaek..vtkdlvaHltlq 52 +L +H+ + ++ +++ C C + +k+l +H++l+ FUN_000374-T1 402 ALSKHMRVHEKQRDTPYQCKQCLKFfsSSKSLNRHIKLH 440 578888886666677899999986532567888888875 PP == domain 3 score: 16.0 bits; conditional E-value: 8e-06 zf-Di19 4 tCPyCgeef.dvvsLceHvedeHrveskevvCPvCa.ekvtkdlvaHltlqh 53 +C +Cg+ f ++v+L +H+ H ++ + CP+C+ ++ + +l++H+ +h FUN_000374-T1 457 KCQHCGNVFsSAVALSNHMRM-HEKQFRINACPICKvSNYSGSLARHMRKKH 507 699****76156677777765.*************9666778******9999 PP == domain 4 score: 1.4 bits; conditional E-value: 0.29 zf-Di19 4 tCPyCge.efdvvsLceHvedeHrveske 31 +C Cg+ d L H+ H+v++++ FUN_000374-T1 514 RCGKCGKvCADKRVLAVHIAIRHPVKRNS 542 57779996689999999999999998765 PP == domain 5 score: 2.7 bits; conditional E-value: 0.12 zf-Di19 2 eftCPyCgee.fdvvsLceHvedeHrve 28 +f C C+++ +v+sL +H + H+++ FUN_000374-T1 697 SFCCTICKKSfSTVTSLRSHKAS-HTRS 723 69999****82467889999877.6554 PP == domain 6 score: -1.2 bits; conditional E-value: 2 zf-Di19 3 ftCPyCgee.fdvvsLceH 20 f+C Cg+ ++ +L +H FUN_000374-T1 934 FSCGECGKAfISKRNLARH 952 5555566632555555555 PP == domain 7 score: 13.6 bits; conditional E-value: 4.7e-05 zf-Di19 2 eftCPyCgee.fdvvsLceHvedeHrveskevvCPvCae 39 +++C C e+ + ++L++H H++++ + +CP C++ FUN_000374-T1 987 TYECSTCLESfYGGSALVNHQRRIHKDANSNFICPFCDK 1025 789999**96488999*********************85 PP == domain 8 score: 15.2 bits; conditional E-value: 1.5e-05 zf-Di19 2 eftCPyCge.efdvvsLceHvedeHrveskevvCPvCaekvt 42 +f CP+C++ ++ +sL+ H +d H++ s + C C+ + + FUN_000374-T1 1017 NFICPFCDKiFLTRASLLLHKQDLHSS-SDPFTCKHCNGRFS 1057 799******779*************86.56688888876644 PP == domain 9 score: 10.8 bits; conditional E-value: 0.00036 zf-Di19 3 ftCPyCgeefdvv.sLceHvedeHrveskevvCPvCaek..vtkdlvaH 48 + C C e f+++ +L +H H s++ +C++C +++l +H FUN_000374-T1 1167 YLCDVCFEPFKTKiGLNNHKR-SHIGRSEPFICSICHRGfvSKRNLRRH 1214 78999***8776626666655.5*************9553244577777 PP == domain 10 score: 9.0 bits; conditional E-value: 0.0012 zf-Di19 3 ftCPyCgeefdvv.sLceHvedeHrvesk 30 +C yC++ef+ +L +Hv+++H+++ k FUN_000374-T1 1286 WQCQYCEKEFQKRcNLRRHVSKKHAKQPK 1314 58******9876439*********99876 PP == domain 11 score: 4.4 bits; conditional E-value: 0.035 zf-Di19 3 ftCPyCgeef.dvvsLceHvedeHrv 27 +C +C+++f ++ +L++Hve+ H + FUN_000374-T1 1332 WKCQHCERQFrTEFGLLRHVEKRHDK 1357 6899****8625679*********76 PP == domain 12 score: 6.0 bits; conditional E-value: 0.011 zf-Di19 4 tCPyCgeef.dvvsLceHvedeHrvesk 30 +C yCg+ef ++++ +Hv+ +H+ +k FUN_000374-T1 1378 NCLYCGNEFnSIHGIRKHVSRKHPGRKK 1405 799****862789**********98776 PP == domain 13 score: -0.4 bits; conditional E-value: 1.1 zf-Di19 4 tCPyCgeef.dvvsLceHvedeHrve 28 +C yC+++f +v++ ++Hv H++e FUN_000374-T1 1440 RCQYCNRGFpTVSKRYKHVMLVHKEE 1465 799****8636677889999888776 PP == domain 14 score: 1.1 bits; conditional E-value: 0.38 zf-Di19 2 eftCPyCgeefdvvsLc 18 +f C yC+++f ++ c FUN_000374-T1 1537 SFYCRYCKKGFLNKRSC 1553 799******97665544 PP == domain 15 score: -2.5 bits; conditional E-value: 4.9 zf-Di19 5 CPyCgeefdvvsLc 18 C yC++ f +s c FUN_000374-T1 1617 CRYCKKRFLNKSSC 1630 99****87666554 PP == domain 16 score: -2.5 bits; conditional E-value: 4.9 zf-Di19 2 eftCPyCge.efdvvsLceH 20 +f C yC++ f +s +H FUN_000374-T1 1803 NFCCRYCRKwFFARSSRRKH 1822 699****9955666555555 PP == domain 17 score: -1.6 bits; conditional E-value: 2.6 zf-Di19 2 eftCPyCgee.fdvv 15 f+C +C+++ ++v+ FUN_000374-T1 1891 AFPCQHCSRQfITVS 1905 699*****9735555 PP >> HVO_2525_N HVO_2525, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.1 2.9e-05 0.053 19 93 .. 1909 1983 .. 1897 1997 .. 0.86 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.9e-05 HVO_2525_N 19 dhdvsfsavqWeldtaaeeletrlvvegedrealeeGlsalrdhenmkefellskrddvatirtvieetdameti 93 +h++ ++ qW+l ++++++++ v + +d + ++G ++lr+++ ++++e l d+v +i tv+ + + + + FUN_000374-T1 1909 KHNLLVHSKQWNLGSSTSQVNVTAVTDRSDAKFTTHGCRVLRKKSSLHQIEPLGGSDNVMNISTVVYNSEVSASV 1983 577888999********************************************************9887765555 PP >> zf-FPG_IleRS Zinc finger found in FPG and IleRS # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 2.4 4.4e+03 3 13 .. 363 373 .. 361 381 .. 0.83 2 ? 10.3 0.0 0.00038 0.7 1 16 [. 455 470 .. 455 474 .. 0.84 3 ? 1.3 0.2 0.26 4.7e+02 12 29 .. 1008 1025 .. 1005 1026 .. 0.80 4 ? -3.1 1.1 6 1.1e+04 4 24 .. 1049 1067 .. 1046 1067 .. 0.62 5 ? -1.2 0.1 1.5 2.7e+03 19 27 .. 1164 1172 .. 1162 1174 .. 0.81 6 ? -3.1 0.5 6 1.1e+04 3 9 .. 1333 1339 .. 1333 1343 .. 0.75 7 ? -0.8 0.3 1.1 2e+03 3 16 .. 1893 1906 .. 1892 1910 .. 0.76 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 2.4 zf-FPG_IleRS 3 kCpRCwnyiek 13 +C+ C+ +++ FUN_000374-T1 363 VCKICGKAFSD 373 7*****99887 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00038 zf-FPG_IleRS 1 GekCpRCwnyiekvgv 16 G+kC++C+n +++ + FUN_000374-T1 455 GQKCQHCGNVFSSAVA 470 9*********998876 PP == domain 3 score: 1.3 bits; conditional E-value: 0.26 zf-FPG_IleRS 12 ekvgvggrstelCprCqk 29 +++ ++++s+++Cp C k FUN_000374-T1 1008 RRIHKDANSNFICPFCDK 1025 67778999******9976 PP == domain 4 score: -3.1 bits; conditional E-value: 6 zf-FPG_IleRS 4 CpRCwnyiekvgvggrstelC 24 C++C +++++ r+++lC FUN_000374-T1 1049 CKHCNGRFSSKYS--RNNHLC 1067 6666666555555..677777 PP == domain 5 score: -1.2 bits; conditional E-value: 1.5 zf-FPG_IleRS 19 rstelCprC 27 ++++lC+ C FUN_000374-T1 1164 DEPYLCDVC 1172 579****99 PP == domain 6 score: -3.1 bits; conditional E-value: 6 zf-FPG_IleRS 3 kCpRCwn 9 kC++C + FUN_000374-T1 1333 KCQHCER 1339 7888865 PP == domain 7 score: -0.8 bits; conditional E-value: 1.1 zf-FPG_IleRS 3 kCpRCwnyiekvgv 16 +C++C + + +v+ FUN_000374-T1 1893 PCQHCSRQFITVSR 1906 9****987777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2230 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1475 (0.0577412); expected 510.9 (0.02) Passed bias filter: 465 (0.0182032); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 76 (0.00297514); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.71u 0.42s 00:00:01.12 Elapsed: 00:00:00.51 # Mc/sec: 17804.64 // Query: FUN_000375-T1 [L=151] Description: FUN_000375 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.024 15.6 0.2 0.044 14.8 0.1 1.6 1 TIR_2 TIR domain 0.032 15.1 0.0 0.045 14.6 0.0 1.2 1 Bflower 4-fold beta flower protein 0.19 12.4 0.0 0.45 11.2 0.0 1.7 1 NagA_N NagA composite domain 0.19 12.3 1.2 11 6.6 0.1 2.8 3 DnaB DnaB-like helicase N terminal domain Domain annotation for each model (and alignments): >> TIR_2 TIR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.1 6.9e-06 0.044 1 64 [. 4 66 .. 4 118 .. 0.83 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 6.9e-06 TIR_2 1 VfiSYagedrewaewladaLeaa.girvw.ldewdikpgddwveeieeaieesdrvvavlspayle 64 V i ++++d+ +l+d L+++ g +v + +d d ++++e+++ es++vv+v+++++ + FUN_000375-T1 4 VLILHTQADQRRTLQLKDFLQEKlGSSVHvITVRDA-LED--NSTLEDQLFESACVVFVYTQESEK 66 7899****************5554999953788873.344..48999**************99874 PP >> Bflower 4-fold beta flower protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 7e-06 0.045 19 74 .. 78 134 .. 72 151 .] 0.73 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 7e-06 Bflower 19 tiydwdgkpv.AyleddkVyslnG.rhlGwledgvllDregkvvaftkgasgvgpskp 74 +++ +dg + A+le+d+V++ h Gw +++l+D+ k+++ +++ +++p FUN_000375-T1 78 HFVIFDGSIIkAFLEQDEVIERVIaVHFGWRPEQWLYDKLHKRIFHVSETLAL-KENP 134 56666666644*******9998866**************99999988888764.3443 PP >> NagA_N NagA composite domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 7.1e-05 0.45 16 41 .. 75 100 .. 70 105 .. 0.86 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 7.1e-05 NagA_N 16 LddHAvvienelIeavvpqaeLpagi 41 Ld+H v+ ++ +I+a + q+e+ + + FUN_000375-T1 75 LDNHFVIFDGSIIKAFLEQDEVIERV 100 9*******************986655 PP >> DnaB DnaB-like helicase N terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 0.015 96 54 74 .. 28 48 .. 22 70 .. 0.81 2 ? 0.4 0.2 0.15 9.5e+02 28 57 .. 66 97 .. 57 105 .. 0.65 3 ? 6.6 0.1 0.0017 11 15 56 .. 89 134 .. 82 140 .. 0.70 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.015 DnaB 54 gkpiDlvtvaeelekkgklee 74 g ++ ++tv++ le+++ le+ FUN_000375-T1 28 GSSVHVITVRDALEDNSTLED 48 678899************998 PP == domain 2 score: 0.4 bits; conditional E-value: 0.15 DnaB 28 dilkpedFydpahreIFe..ailelyekgkpi 57 + l++ F ++h IF+ +i++ e+++ i FUN_000375-T1 66 KHLEEGEFDLDNHFVIFDgsIIKAFLEQDEVI 97 56777788888888888632455555555544 PP == domain 3 score: 6.6 bits; conditional E-value: 0.0017 DnaB 15 alLldpeaidevadil...kpedF.ydpahreIFeailelyekgkp 56 a L ++e i++v+++ +pe++ yd+ h++IF + ++l+ k++p FUN_000375-T1 89 AFLEQDEVIERVIAVHfgwRPEQWlYDKLHKRIFHVSETLALKENP 134 5566666666666554333455543999***********9988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (151 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 844 (0.0330397); expected 510.9 (0.02) Passed bias filter: 577 (0.0225876); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1535.44 // Query: FUN_000376-T1 [L=629] Description: FUN_000376 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-10 40.7 19.7 3.8e-10 39.8 19.7 1.4 1 Ion_trans Ion transport protein 1.2e-09 38.4 23.8 2.7e-08 34.0 10.9 2.6 3 PKD_channel Polycystin cation channel 0.0016 19.5 0.0 0.24 12.5 0.0 2.6 2 Ank_2 Ankyrin repeats (3 copies) 0.0027 18.4 0.4 0.45 11.4 0.1 2.9 2 Ank Ankyrin repeat 0.0086 17.0 0.1 0.64 11.3 0.1 3.1 2 Ank_3 Ankyrin repeat ------ inclusion threshold ------ 0.21 12.6 8.6 0.78 10.8 1.7 3.3 3 YoqO YoqO-like protein 1.3 9.8 6.1 22 5.9 3.9 3.2 2 Phage_holin_2 Putative phage holin family 2 Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.8 19.7 1e-13 3.8e-10 13 240 .. 334 548 .. 314 551 .. 0.73 Alignments for each domain: == domain 1 score: 39.8 bits; conditional E-value: 1e-13 Ion_trans 13 llntvvlaletyfqp..........eekel......klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil....ses 88 ++++ + + ++eil l++tv+++ e l +++ + +Y+++++n++D++ +++ l ++ l s FUN_000376-T1 334 SFSLI---------SgsmkadptqyK---GaaeflrGFCEILTLIMTVFYICEELNQMRKERR--TYFQEWMNLFDWLGLIFILCIIPLrfagS-- 413 22222.........222222222231...13456669**********************9888..************99998888666665432.. PP Ion_trans 89 keslsllrvlrllrllrllrlirrleglrtlvnslirslks.llnlllllllvlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwl 183 + ++++ ++ l+ +lr+++++ ++ + ++l r++++ + +++ ++++v+f f g +lf ++ ++ +F+ f + ll+ FUN_000376-T1 414 SVQWTMASLAFLFNFLRIFKFACVTRFTGLYTKTLARIINEdVTRFMSVFAIVFFSFC--G-SLF-----------LSARTSKQSFSGFEDVLLSG 495 357888888888899****99865555556779****998625566666666655555..5.456...........356778899*********** PP Ion_trans 184 fqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqelte 240 f+ l+ e ++ + + +++ ++++++++++++ + v+lln+lia +++++ ++++ FUN_000376-T1 496 FRALS-E--QQPITEDYSGF-NWLSILLMLTYMGTVVVILLNILIAQMSTTYTQAKK 548 **777.4..46666666666.9******************************99886 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 1.7 6.2e+03 192 205 .. 317 332 .. 304 340 .. 0.51 2 ! 13.2 1.5 1.7e-05 0.061 12 57 .. 359 406 .. 348 411 .. 0.83 3 ! 34.0 10.9 7.3e-12 2.7e-08 95 224 .. 414 545 .. 406 546 .. 0.92 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.7 PKD_channel 192 rvLGp..llllalvfl 205 r+L++ ++++++ + FUN_000376-T1 317 RFLSIqaMCYVIFLLA 332 4444422233333333 PP == domain 2 score: 13.2 bits; conditional E-value: 1.7e-05 PKD_channel 12 lievvfvvfvlyfvveeilkirkerasylrsvwnlldla..ivvlsvv 57 +e++ +++ ++++ ee+ ++rker+ y+++ nl d + i++l+++ FUN_000376-T1 359 FCEILTLIMTVFYICEELNQMRKERRTYFQEWMNLFDWLglIFILCII 406 699**********************************85226666654 PP == domain 3 score: 34.0 bits; conditional E-value: 7.3e-12 PKD_channel 95 llriilavlvflt.tlkllkvlrfnktmslltktlaral.kdlagfalvivilflayaqlgvllfGtqasnfsnlvksiltlfrlilgdfqytele 188 +++ ++a+l fl l+++k+ + + l tktlar + +d+ f v++i+f++++ + l t + fs + l fr + ++ te FUN_000376-T1 414 SVQWTMASLAFLFnFLRIFKFACVTRFTGLYTKTLARIInEDVTRFMSVFAIVFFSFCGSLFLSARTSKQSFSGFEDVLLSGFRALSEQQPITEDY 509 566678888887538**********************87358***********************************************9999888 PP PKD_channel 189 sgnrvLGpllllalvflvifillnlflaiindsyee 224 sg +L++ll+l+++ v++illn+++a + +y++ FUN_000376-T1 510 SGFNWLSILLMLTYMGTVVVILLNILIAQMSTTYTQ 545 9*******************************9985 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 6.5e-05 0.24 27 51 .. 89 119 .. 64 159 .. 0.60 2 ? 4.1 0.0 0.026 96 27 64 .. 276 319 .. 263 331 .. 0.68 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 6.5e-05 Ank_2 27 k......ngetaLhlAaknghleivklLleh 51 ++t Lh+Aa+ + l++ k L+++ FUN_000376-T1 89 FrdeedeLKRTLLHYAAEMNFLHVTKTLVKK 119 0222333455555555555555555555554 PP == domain 2 score: 4.1 bits; conditional E-value: 0.026 Ank_2 27 k....ngetaLhlAaknghlei.....vklLlehgadvndnngrtaL 64 + + ++ Lhl ak+ ++++ v+ L++ ++ +++gr L FUN_000376-T1 276 ElfdrKSKSCLHLIAKSKNKDAlqhpvVRMLIKTKW---KSYGRRFL 319 3344467899**999999888777776899998633...36777666 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.1 0.00012 0.45 3 23 .. 98 118 .. 97 125 .. 0.88 2 ? 3.7 0.0 0.037 1.4e+02 4 22 .. 284 307 .. 282 310 .. 0.80 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00012 Ank 3 nTPLHlAaraghlevvklLLk 23 +T LH+Aa+++ l+v k L+k FUN_000376-T1 98 RTLLHYAAEMNFLHVTKTLVK 118 79******99*********94 PP == domain 2 score: 3.7 bits; conditional E-value: 0.037 Ank 4 TPLHlAaragh.....levvklLL 22 ++LHl a+ ++ + vv++L+ FUN_000376-T1 284 SCLHLIAKSKNkdalqHPVVRMLI 307 79**99955555799999999999 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.1 0.00017 0.64 3 25 .. 98 120 .. 96 124 .. 0.89 2 ? 2.0 0.0 0.19 7.1e+02 4 23 .. 284 308 .. 281 313 .. 0.74 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00017 Ank_3 3 ntpLhlAarngrleivklLlekl 25 +t+Lh+Aa+ + l + k L++k+ FUN_000376-T1 98 RTLLHYAAEMNFLHVTKTLVKKC 120 8******************9954 PP == domain 2 score: 2.0 bits; conditional E-value: 0.19 Ank_3 4 tpLhlAarngrl.....eivklLle 23 ++Lhl a++ + ++v++L++ FUN_000376-T1 284 SCLHLIAKSKNKdalqhPVVRMLIK 308 789*******995444445777776 PP >> YoqO YoqO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 1.7 0.00021 0.78 40 110 .. 304 374 .. 301 379 .. 0.80 2 ? 5.4 0.5 0.0097 35 62 105 .. 362 406 .. 347 411 .. 0.70 3 ? 0.0 0.1 0.46 1.7e+03 87 110 .. 513 536 .. 496 549 .. 0.65 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00021 YoqO 40 llYnwDelKkySkkslivlsitlvilvlliaflllkgqelidklsifqglltiakilyiivvlvivlsilk 110 + + ++K+y ++ l +++++ vi+ l + f l+ g+ d + ++ ++ i+ ++ v i FUN_000376-T1 304 RMLIKTKWKSYGRRFLSIQAMCYVIFLLALSFSLISGSMKADPTQYKGAAEFLRGFCEILTLIMTVFYICE 374 5667789******************************9998888877777777777666666666665555 PP == domain 2 score: 5.4 bits; conditional E-value: 0.0097 YoqO 62 lvilvlliaflllkgqeli..dklsifqglltiakilyiivvlviv 105 ++ l++++ ++ + +++ ++ + fq+++ +l +i +l+i+ FUN_000376-T1 362 ILTLIMTVFYIC-EELNQMrkERRTYFQEWMNLFDWLGLIFILCII 406 444455544444.4444441256789***********999999885 PP == domain 3 score: 0.0 bits; conditional E-value: 0.46 YoqO 87 qglltiakilyiivvlvivlsilk 110 + l + ++y+ v+vi l+il+ FUN_000376-T1 513 NWLSILLMLTYMGTVVVILLNILI 536 433344556677777777777765 PP >> Phage_holin_2 Putative phage holin family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.42 1.5e+03 36 55 .. 322 341 .. 306 385 .. 0.55 2 ? 5.9 3.9 0.0059 22 8 87 .. 434 539 .. 427 548 .. 0.85 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.42 Phage_holin_2 36 lsvalalvlllvvlsvlvgd 55 +++ +++ll +++s++ g+ FUN_000376-T1 322 QAMCYVIFLLALSFSLISGS 341 33555555555566655555 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0059 Phage_holin_2 8 avlalvfvllYgl.sarWwrtraGrvlmalsvalalvlllvvlsvlvgd.........................dypgrelvrlvlylllavalla 77 +++++ f+ lY +ar ++ + r + +++ +++ +++ ++ls ++ dy g+ ++ ++l+l+ + +++ FUN_000376-T1 434 FACVTRFTGLYTKtLARIINEDVTRFMSVFAIVFFSFCGSLFLSARTSKqsfsgfedvllsgfralseqqpiteDYSGFNWLSILLMLTYMGTVVV 529 678888999999998899999999999999999999999999999887778888888888888888888888888999999999999999999999 PP Phage_holin_2 78 llvtllreqr 87 +l+ +l +q FUN_000376-T1 530 ILLNILIAQM 539 9999999885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (629 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1315 (0.0514778); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 6129.61 // Query: FUN_000377-T1 [L=61] Description: FUN_000377 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-07 32.3 0.0 1.4e-07 32.2 0.0 1.0 1 ALS2CR8 Amyotrophic lateral sclerosis 2 chromosomal ------ inclusion threshold ------ 0.024 14.8 0.0 0.028 14.6 0.0 1.1 1 CG-1 CG-1 domain 0.14 13.5 0.0 0.17 13.1 0.0 1.2 1 tRNA-synt_1c_C2 tRNA synthetases class I (E and Q), anti-cod Domain annotation for each model (and alignments): >> ALS2CR8 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.2 0.0 1.6e-11 1.4e-07 78 135 .. 1 54 [. 1 60 [. 0.93 Alignments for each domain: == domain 1 score: 32.2 bits; conditional E-value: 1.6e-11 ALS2CR8 78 ikkirkFpeykvekdpkrekkkvrdelkkdllaLknkpveiegelrfyvklpliseHe 135 +++++ F yk+ ++ r ++ ++d+l++d kn++ + e+r+y++lpl+++H+ FUN_000377-T1 1 MSEVVRFAGYKITDNTERLRRGMSDRLRTD---VKNGQR-PQFERRIYISLPLEEDHK 54 689***************************...999999.5****************7 PP >> CG-1 CG-1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 3.3e-06 0.028 63 105 .. 9 50 .. 5 59 .. 0.77 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.3e-06 CG-1 63 gktvrEdhekLkvggeeviecyyahseeeetfqRRiYwlldse 105 g ++ ++ e+L+ g + + + +++ + ++f+RRiY+ l e FUN_000377-T1 9 GYKITDNTERLRRGMSDRLRTD-VKNGQRPQFERRIYISLPLE 50 667888999***9999999975.788899********976544 PP >> tRNA-synt_1c_C2 tRNA synthetases class I (E and Q), anti-codon binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 2.1e-05 0.17 33 67 .. 12 45 .. 3 47 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2.1e-05 tRNA-synt_1c_C2 33 lnpdslkvleeglaEpalanlkegdivQFeReGYf 67 ++ +++ l++g+ + ++k g++ QFeR+ Y FUN_000377-T1 12 ITDNTE-RLRRGMSDRLRTDVKNGQRPQFERRIYI 45 555555.579*********************9885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (61 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 438 (0.0171462); expected 510.9 (0.02) Passed bias filter: 382 (0.014954); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 618.43 // Query: FUN_000378-T1 [L=421] Description: FUN_000378 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-115 385.3 0.0 3.2e-115 385.0 0.0 1.1 1 Ferrochelatase Ferrochelatase Domain annotation for each model (and alignments): >> Ferrochelatase Ferrochelatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 385.0 0.0 1.2e-119 3.2e-115 1 316 [. 67 386 .. 67 387 .. 0.97 Alignments for each domain: == domain 1 score: 385.0 bits; conditional E-value: 1.2e-119 Ferrochelatase 1 ktavlLlnlGgPekpeevrpflknllsdrrvielplllqkllakiilkerskkvaekYekigggSPllkitrkqaeaLekalderg...aevkvy 92 kt++lLln+GgPe+ +v++fl +l+sdr+++ lp q +a +i+++r++k++e+Y+kigggSP++ +t+ q e + + lde a++k+y FUN_000378-T1 67 KTGILLLNMGGPEASTDVHDFLLRLFSDRDLMVLP--AQSKMAAWIARRRTPKIQEQYQKIGGGSPIKMWTEIQGEGMVNLLDEMCpdtAPHKFY 159 79*******************************98..9*********************************************998999****** PP Ferrochelatase 93 lamrygkPsiedaleelkkdgverivvlplyPqysssttgssleelaralkk..kreapevkvirsyydhpgyiealaesikealeelk..eekk 183 +++ry +P++edal++++kdg+er+v++ +yPqys+sttgssl++++r++k+ + ++++vi+++++hpg+++a+ae++k++l +++ ++k+ FUN_000378-T1 160 IGFRYVNPLTEDALDQMEKDGIERAVAFTQYPQYSCSTTGSSLNAIYRHYKEkgYGPPMKWSVIDRWPTHPGLVKAFAENVKTELLKFPadAQKD 254 **************************************************8867778899****************************9875557 PP Ferrochelatase 184 dkllfsaHglPekiiekkgdpYqaqveetvrlvaeklglseqyelayQSrvGpeeWlePstddtleelakkgvkkvlvvpigFvsDhlEtleeld 278 +++lfsaH+lP+k++ ++gdpY+++v++tv+ v+e l++s+ y+l++QS+vGp+ Wl+P+t+d+++ l kkg+k+vl+vpi+F+sDh+Etl+eld FUN_000378-T1 255 VVILFSAHSLPMKVV-ERGDPYPQEVAATVQRVMETLNTSHPYRLVWQSKVGPMSWLGPQTEDAIKGLGKKGHKHVLLVPIAFTSDHIETLHELD 348 ***************.56***************************************************************************** PP Ferrochelatase 279 ieykelaeeaggekfrrvpalndspefiealadlveek 316 iey e+a+eag+e++rr+++lndsp+fi+a+ad+v+++ FUN_000378-T1 349 IEYSEVAHEAGIENIRRAASLNDSPTFIHAMADVVKNH 386 ***********************************998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (421 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 804 (0.0314739); expected 510.9 (0.02) Passed bias filter: 738 (0.0288902); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.58s 00:00:00.95 Elapsed: 00:00:00.47 # Mc/sec: 3651.28 // Query: FUN_000379-T1 [L=160] Description: FUN_000379 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-16 60.4 0.2 4.6e-16 59.5 0.2 1.5 1 MAM MAM domain, meprin/A5/mu Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.5 0.2 1.8e-20 4.6e-16 1 124 [. 50 152 .. 50 159 .. 0.90 Alignments for each domain: == domain 1 score: 59.5 bits; conditional E-value: 1.8e-20 MAM 1 CdFeegslCgwtqdesddadWervsaasektgpssdhtetgsGhyllletssaeegqtarLlspllpasaksqClrFwyhmsgsskgtlrvllree 96 CdFe++ lCgw ++ + +W+r+ + + ht +++G+ +++++ ++++g+ a+L+ + ++ + +C++Fwy m+g++ ++l++++ ++ FUN_000379-T1 50 CDFEND-LCGWKNARYNTINWSRR--------RLRTHT-NEKGYCIFMNARKGRAGDVASLVLKHFSGK---KCMSFWYSMKGRGIDQLEIYVDYT 132 ******.****99999999**998........478899.9************9*********9999887...7********************987 PP MAM 97 geekeellwsisgeqgksWkeaevtlsk 124 ++ g+q++ Wk+ae+++s FUN_000379-T1 133 QTF--------VGKQSRGWKKAELDISG 152 665........78999999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 716 (0.028029); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1630.64 // Query: FUN_000380-T1 [L=192] Description: FUN_000380 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-29 102.2 0.1 5.8e-29 102.0 0.1 1.1 1 Trypsin Trypsin 0.00024 22.0 0.0 0.00031 21.6 0.0 1.3 1 DUF1986 Domain of unknown function (DUF1986) 0.0097 17.1 0.0 0.018 16.3 0.0 1.4 1 Trypsin_2 Trypsin-like peptidase domain ------ inclusion threshold ------ 0.035 14.4 0.1 0.28 11.5 0.0 2.1 2 MAM MAM domain, meprin/A5/mu Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.0 0.1 9.1e-33 5.8e-29 1 101 [. 87 191 .. 87 192 .] 0.97 Alignments for each domain: == domain 1 score: 102.0 bits; conditional E-value: 9.1e-33 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegs..eqklkvekvivhpnynsdtldnDiall 92 ivgg+ a+++++pwq++l +s+++fCGGsli ++wvlTAaHC+++ ++s++++lg+h++ +++s q +kv k++ h+++n +t+ nD+al+ FUN_000380-T1 87 IVGGNAANENEWPWQANLMTNSKRQFCGGSLIAKQWVLTAAHCLEQedTKSFQIRLGAHKRGGKNPSvvVQDFKVMKIFRHEKFNGQTMSNDVALV 182 89*********************9*************************************999999889************************** PP Trypsin 93 klkspvtlg 101 kl+++++l+ FUN_000380-T1 183 KLDREAKLN 191 ****99886 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.0 4.9e-08 0.00031 1 51 [. 98 147 .. 98 192 .] 0.73 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 4.9e-08 DUF1986 1 wPwladvyleGd.licsGvlidkswvlvsesclsdvdlehsyvsvvlGgakt 51 wPw a++ + + +c G li k+wvl cl + d + + lG++k FUN_000380-T1 98 WPWQANLMTNSKrQFCGGSLIAKQWVLTAAHCLEQEDT--KSFQIRLGAHKR 147 9*******9986268******************99987..445666777764 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 2.8e-06 0.018 3 63 .. 115 186 .. 113 191 .. 0.74 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 2.8e-06 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaavvaekvsvaladgreyaatvvaadp..............elDlallkvsed 63 G +++++ vlT+aH++++++++ + + ++ ++g+ ++ v +++ D+al+k+ ++ FUN_000380-T1 115 GSLIAKQW-VLTAAHCLEQEDTKSF-QIRLGAHKRGGKNPSVVVQDFKVmkifrhekfngqtmSNDVALVKL-DR 186 66788887.********99999999.566666666666666666666667777787888865555*****99.33 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 4.3e-05 0.28 126 157 .. 25 55 .. 5 56 .. 0.81 2 ? 0.7 0.0 0.093 6e+02 114 151 .. 121 160 .. 94 164 .. 0.77 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 4.3e-05 MAM 126 ekefqvvfeavrgggsegdialDdislsegeC 157 + + q+++ avrg+++ g+ia+Ddi + +C FUN_000380-T1 25 NLSSQILILAVRGKSKFGYIAIDDILF-LDTC 55 55679********************96.5666 PP == domain 2 score: 0.7 bits; conditional E-value: 0.093 MAM 114 sWkeaevtlskl..ekefqvvfeavrgggsegdialDdis 151 +W + ++ +k+fq+ + a ++gg++ ++ + d + FUN_000380-T1 121 QWVLTAAHCLEQedTKSFQIRLGAHKRGGKNPSVVVQDFK 160 5655554444333589999999999999888888888866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (192 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 456 (0.0178509); expected 510.9 (0.02) Passed bias filter: 396 (0.0155021); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1913.83 // Query: FUN_000381-T1 [L=99] Description: FUN_000381 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-26 93.3 3.9 3e-26 93.1 3.9 1.0 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.1 3.9 1.2e-30 3e-26 101 189 .. 2 93 .. 1 97 [. 0.94 Alignments for each domain: == domain 1 score: 93.1 bits; conditional E-value: 1.2e-30 Trypsin 101 gdavrpiclpa.assslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsayggkvtdnmicagak.ggkdacqGDSGGPlvcsdg 189 +++v+ +clp+ + +++ g++c+++GwG+ +++g ++d+l+ev+vp+vs++ c++ay++ + +micag + ggkdacqGDSGGP+vc++g FUN_000381-T1 2 NSQVNLVCLPDkSVPDPTHGQMCWTTGWGTLSSGGgQPDVLHEVQVPAVSQAICSKAYKNGIDATMICAGLQkGGKDACQGDSGGPFVCGQG 93 789********6556669************999999************************************999**************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 387 (0.0151497); expected 510.9 (0.02) Passed bias filter: 281 (0.0110002); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1005.02 // Query: FUN_000382-T1 [L=184] Description: FUN_000382 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-50 172.6 0.2 1.7e-50 172.3 0.2 1.0 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 172.3 0.2 6.8e-55 1.7e-50 63 220 .] 13 177 .. 2 177 .. 0.94 Alignments for each domain: == domain 1 score: 172.3 bits; conditional E-value: 6.8e-55 Trypsin 63 egseqklkvekvivhpnynsdtldnDiallklkspvtlgdavrpiclpaassslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsa.. 155 + +eqk+k+ k+i hp+yn++t+ nDiallkl++++tl ++++ +clp++++ +g+tcl++GwG+tk++g ++d+l ++vp+v ++ c++a FUN_000382-T1 13 RNTEQKFKLVKIIEHPGYNERTMSNDIALLKLQRKATLDNHTNLACLPTSDA--LEGKTCLITGWGTTKANGeQADKLLVAKVPIVRQAICKTAyn 106 4569*********************************************666..99**************************************55 PP Trypsin 156 .yggkvtdnmicagak.ggkdacqGDSGGPlvcsdg....eliGivswgkgcasgnkpgvytrvssyadwi 220 +g+++ +m+cag++ ggkd+cqGDSGGPlvc dg l+G++swg gca+++k+gvy+rv+++++wi FUN_000382-T1 107 kLGADIDASMVCAGFPkGGKDSCQGDSGGPLVCIDGngayGLHGVTSWGIGCAQKGKYGVYARVNYLLKWI 177 55555***********999********************99*****************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 398 (0.0155803); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.58s 00:00:00.87 Elapsed: 00:00:00.46 # Mc/sec: 1622.69 // Query: FUN_000383-T1 [L=809] Description: FUN_000383 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (809 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3282 (0.128479); expected 510.9 (0.02) Passed bias filter: 449 (0.0175768); expected 510.9 (0.02) Passed Vit filter: 94 (0.00367978); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.70u 0.47s 00:00:01.17 Elapsed: 00:00:00.46 # Mc/sec: 7110.01 // Query: FUN_000384-T1 [L=425] Description: FUN_000384 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-22 79.5 0.3 7e-22 78.0 0.3 1.9 1 FCH Fes/CIP4, and EFC/F-BAR homology domain 2e-13 50.2 0.1 3.5e-13 49.4 0.1 1.4 1 SH3_1 SH3 domain 5.8e-13 48.8 0.0 1.2e-12 47.8 0.0 1.6 1 SH3_2 Variant SH3 domain 2.2e-10 40.7 0.0 4.3e-10 39.8 0.0 1.5 1 SH3_9 Variant SH3 domain 6e-05 22.9 14.3 0.0036 17.1 14.3 2.1 1 GMIP-like_FCH GEM-interacting protein-like, FCH domain ------ inclusion threshold ------ 0.086 13.1 2.0 0.91 9.8 0.0 2.6 2 Poxv_Bcl-2-like Poxvirus Bcl-2-like proteins 1.3 9.8 21.2 3.3 8.5 11.1 2.6 2 Rab11-FIP3 Rab11-FIP3-like domain 2 7.4 12.4 2.8 6.9 12.4 1.1 1 Peptidase_S46 Peptidase S46 2.2 8.7 13.7 0.18 12.3 9.0 1.5 2 Phage_scaffold Phage capsid assembly scaffolding protein Domain annotation for each model (and alignments): >> FCH Fes/CIP4, and EFC/F-BAR homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.0 0.3 2.5e-25 7e-22 1 77 [. 18 89 .. 18 90 .. 0.97 Alignments for each domain: == domain 1 score: 78.0 bits; conditional E-value: 2.5e-25 FCH 1 gfkvLlkrlkqgiklleelakflkeRaeiEeeYakkLqklakkylkkkkepedeegtlkkawdellteteqlakqhl 77 gf+vL+kr+++g+++++++++fl++Ra +Ee+Y+k+L ++a+++++k e e gtlk++w++l+tete+++k h FUN_000384-T1 18 GFDVLCKRMRDGKQMCQDFEEFLRQRADAEEKYGKSLIRIAESAKGK--E-EI--GTLKESWEVLRTETENMGKLHV 89 8*********************************************8..7.88..********************95 PP >> SH3_1 SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.4 0.1 1.2e-16 3.5e-13 1 48 [] 376 421 .. 376 421 .. 0.96 Alignments for each domain: == domain 1 score: 49.4 bits; conditional E-value: 1.2e-16 SH3_1 1 vAlYDYeaeesdELsfkkGdviivleksedgWwkgrlkdggkeGliPs 48 +A +DYea+ ++ELsfk Gd i+++ k+++ Ww g+ + gk+G++P+ FUN_000384-T1 376 RASFDYEAQGAEELSFKAGDLIKLCYKEDSTWWCGEVH--GKKGMFPK 421 699***********************************..79*****5 PP >> SH3_2 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.8 0.0 4.2e-16 1.2e-12 1 53 [. 374 425 .] 374 425 .] 0.94 Alignments for each domain: == domain 1 score: 47.8 bits; conditional E-value: 4.2e-16 SH3_2 1 ygrvifdyvgtdkngLslkkGdvvkVlggkdddgwwegetgGrkGlvPstave 53 y+r+ fdy+++ +++Ls+k+Gd++k+ k+d ww ge++G+kG +P +ve FUN_000384-T1 374 YYRASFDYEAQGAEELSFKAGDLIKLC-YKEDSTWWCGEVHGKKGMFPKAFVE 425 8*************************9.6777799999**********99986 PP >> SH3_9 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.8 0.0 1.5e-13 4.3e-10 1 49 [] 377 425 .] 377 425 .] 0.97 Alignments for each domain: == domain 1 score: 39.8 bits; conditional E-value: 1.5e-13 SH3_9 1 AlypyqpkeddeLslqeGdvitvieesedgWlegentGrtGlvPanyve 49 A ++y+++ ++eLs+ +Gd+i + ++++ W+ ge +G +G +P+ +ve FUN_000384-T1 377 ASFDYEAQGAEELSFKAGDLIKLCYKEDSTWWCGEVHGKKGMFPKAFVE 425 679*********************999********************97 PP >> GMIP-like_FCH GEM-interacting protein-like, FCH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 14.3 1.3e-06 0.0036 2 281 .. 17 271 .. 16 273 .. 0.81 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 GMIP-like_FCH 2 gGvdvlleylkaeeesvkeLlafvdkranYeeefakslnkivekvkvvileqyrglkayycsangltvsqsmlssiylltketdelLltleaetla 97 G+dvl ++ ++ ++ +f +ra+ ee + ksl +i+e +k e+ l+ + + + e ++ l ++ FUN_000384-T1 17 AGFDVLCKRMRDGKQMCQDFEEFLRQRADAEEKYGKSLIRIAESAKG--KEE-----------------IGTLKESWEVLRTETENMGKLHVSLAH 93 5999***************************************9943..233.................3578999*****************999 PP GMIP-like_FCH 98 slkrdllkdlakkrvelvksrkklkeqdfldevklmqeavtvLrkaketYvqrkeelealkkespedpppqaapgsskqqearrkeiekaeaklqk 193 +l +l + + r+ rkk+ e +++ +++ + k tY q+ e +a +d ++ sk++e+ r + ka++ +++ FUN_000384-T1 94 QLMENLEHIVRDFRESQRDKRKKVEE-SVKRAQRNKKNSYDSNVRNKRTYEQKCREADA-----ADDALKKSVSLVSKDEEKLRTKLGKAKTAVEQ 183 99995555555566666668888888.66677777888899999999999998776554.....45779999999********************* PP GMIP-like_FCH 194 aeeeYksyvekanrvrdDleekkikivrlvrklvfafdevlkrvtlGlaelldesaeaasrvfaalaeCvdkievneilvefveakqt 281 a Y+ v+ + r e+++ + l++ l+ + l+ + + ++ + + + + + v+ + f+ kqt FUN_000384-T1 184 ADTAYQNSVRMLEDARVVWEKEMDQCCDLFQSLEEERIAFLRNAVWAYTNMASLNYVKLDEECELVRKSLELCTVESDIHLFISMKQT 271 *********************************9999888888777666666555555555555555555555555555555555555 PP >> Poxv_Bcl-2-like Poxvirus Bcl-2-like proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.0 0.00032 0.91 53 88 .. 27 62 .. 22 89 .. 0.80 2 ? 1.7 0.5 0.1 2.8e+02 72 110 .. 92 130 .. 88 140 .. 0.73 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00032 Poxv_Bcl-2-like 53 lnrekiGklFkeLmkfddlAkkkygkdlikliknll 88 ++ +++++ F e++ + +A++kygk+li ++++ + FUN_000384-T1 27 RDGKQMCQDFEEFLRQRADAEEKYGKSLIRIAESAK 62 566788999**********************99986 PP == domain 2 score: 1.7 bits; conditional E-value: 0.1 Poxv_Bcl-2-like 72 Akkkygkdlikliknllkldsd..iknfkkfiklkekidkd 110 A + + ++l++++ +++++++d +k +++++ +++++ + FUN_000384-T1 92 AHQLM-ENLEHIVRDFRESQRDkrKKVEESVKRAQRNKK-N 130 66667.59*********9999997666667777777776.2 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 6.6 0.033 93 66 121 .. 63 119 .. 33 128 .. 0.67 2 ? 8.5 11.1 0.0012 3.3 20 123 .. 118 220 .. 115 222 .. 0.87 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.033 Rab11-FIP3 66 leeEnseLrsevprlkaqlerleeekqklqdelee.lslelkeereeerkledklsq 121 +eE+ +L+++ + l++++e + + + +l +l+e l++ +++ re++r+ ++k+++ FUN_000384-T1 63 GKEEIGTLKESWEVLRTETENMGKLHVSLAHQLMEnLEHIVRDFRESQRDKRKKVEE 119 4789999***************99988888887664555555555555555555433 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0012 Rab11-FIP3 20 EEqlkeqelraeerleeeqrrhrealsrleRekelelenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelkeereeerkl 115 EE +k ++ ++ + + r++ ++ + Re++ + l++ ++ + ++ ++Lr+++ + k+ +e+++ q+ le+++ ++e+++ +l FUN_000384-T1 118 EESVKRAQRNK-KNSYDSNVRNKRTYEQKCREADAADDALKKSVSLVSKDEEKLRTKLGKAKTAVEQADTAYQNSVRMLEDARVVWEKEMDQCCDL 212 77777666444.444666778888899999*************************************************************99888 PP Rab11-FIP3 116 edklsqer 123 ++l++er FUN_000384-T1 213 FQSLEEER 220 88888776 PP >> Peptidase_S46 Peptidase S46 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 12.4 0.00099 2.8 328 515 .. 30 221 .. 23 238 .. 0.66 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.00099 Peptidase_S46 328 qaeeaaLrawlkkdpereekygdalselealqkekrklaeesvyleeaassesel....lslarklvrlaeerekpdeereegyqesalealeksl 419 +++ +++++ l++ ++ eekyg+ l ++++ k k+++ + e + ++ ++ +sla++l++ e+ ++ q+++ +++e+s+ FUN_000384-T1 30 KQMCQDFEEFLRQRADAEEKYGKSLIRIAESAKGKEEIGTLKESWEVLRTETENMgklhVSLAHQLMENLEHIV----RDFRESQRDKRKKVEESV 121 678899**********************9999988876555444444444444440002344555544333333....444677778888888888 PP Peptidase_S46 420 eekdkdldakvdkavlaasleeyreqlgkdklpavdkllgkks..kedlekvadslvaktkladeakrk..allegekkaveaskDpliklaaala 511 ++ +++ ++++d v ++ e + + + +a++k ++ s +e+l++ + + + + ad a+ + ++le ++ e++ D+ +l+++l FUN_000384-T1 122 KRAQRNKKNSYDSNVRNKRTYEQKCREADAADDALKKSVSLVSkdEEKLRTKLGKAKTAVEQADTAYQNsvRMLEDARVVWEKEMDQCCDLFQSLE 217 88888888888888887776555544444444677776665552256666655555444444454443311567777888899***********97 PP Peptidase_S46 512 dara 515 ++r FUN_000384-T1 218 EERI 221 7765 PP >> Phage_scaffold Phage capsid assembly scaffolding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 3.5 9.8e+03 33 41 .. 64 72 .. 35 87 .. 0.48 2 ? 12.3 9.0 6.3e-05 0.18 15 90 .. 113 192 .. 92 197 .. 0.84 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 3.5 Phage_scaffold 33 kakldklke 41 k+++ +lke FUN_000384-T1 64 KEEIGTLKE 72 333333333 PP == domain 2 score: 12.3 bits; conditional E-value: 6.3e-05 Phage_scaffold 15 qidkimaengkdkkeyvpkakldklkeekkelkkqlkeadkqleelkkk......dneelkkkieelqeknkkkkaeyeakl 90 + +k+ + ++ ++k +d+ k +++++ ead+ ++lkk+ d e+l++k+ + +++ ++++++y++ + FUN_000384-T1 113 KRKKVEESVKRA--QRNKKNSYDSNVRNKRTYEQKCREADAADDALKKSvslvskDEEKLRTKLGKAKTAVEQADTAYQNSV 192 333444444455..7789************************************999******************9999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (425 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2904 (0.113682); expected 510.9 (0.02) Passed bias filter: 933 (0.0365238); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4089.90 // Query: FUN_000385-T1 [L=119] Description: FUN_000385 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.68 10.6 13.2 0.9 10.3 13.2 1.2 1 UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 Domain annotation for each model (and alignments): >> UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 13.2 3.5e-05 0.9 10 90 .. 2 87 .. 1 107 [. 0.74 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 3.5e-05 UPAR_LY6_2 10 cftcekaadnyecnrwaedkycpretkycltvhklesegksvsvtkkcaaleecllv..gc....reskeeehkectsccegnicnv 90 c+ ce+a ec+r + c + c+ +h +++g++ + c +++ c+++ c + ++++ h ++ ce c+ FUN_000385-T1 2 CYECEDAITAEECDRRQKRETCRSLEETCMKAHYKTASGRTEEF-RGCSEKSRCENMrrKCergeKIQQNDLHLDPITKCEVACCDT 87 ****************************************9875.567777777654224511113344445556667777777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1246 (0.0487767); expected 510.9 (0.02) Passed bias filter: 447 (0.0174985); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1183.46 // Query: FUN_000386-T1 [L=103] Description: FUN_000386 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 753 (0.0294774); expected 510.9 (0.02) Passed bias filter: 572 (0.0223919); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1048.61 // Query: FUN_000387-T1 [L=894] Description: FUN_000387 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-65 215.5 15.5 9.4e-17 61.7 0.1 5.1 6 PDZ PDZ domain 1.2e-32 113.2 2.7 2.4e-32 112.2 2.7 1.5 1 FERM_M FERM central domain 1.5e-31 108.4 6.0 1e-07 32.1 0.1 4.7 4 PDZ_6 PDZ domain 6.9e-16 58.8 0.5 0.011 16.5 0.0 4.6 4 PDZ_2 PDZ domain 4.6e-15 55.7 0.3 1.3e-14 54.3 0.1 1.9 2 FERM_N FERM N-terminal domain 1.8e-14 54.5 0.1 3.9e-14 53.3 0.1 1.5 1 FERM_C FERM C-terminal PH-like domain 0.002 18.5 0.0 0.0056 17.0 0.0 1.7 1 SNX17-27-31_F1_FERM Sortin nexin 17/27/31, FERM domain, F1 l 0.007 16.1 0.2 5 6.6 0.0 3.2 3 DUF6288 Family of unknown function (DUF6288) ------ inclusion threshold ------ 0.079 13.5 0.1 0.45 11.1 0.0 2.3 2 RA_2 RA like domain Domain annotation for each model (and alignments): >> PDZ PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 3.1 8.9e+03 38 55 .. 4 23 .. 2 26 .. 0.71 2 ? -3.9 0.1 9 2.6e+04 6 18 .. 232 244 .. 229 253 .. 0.77 3 ! 50.0 0.1 1.4e-16 4e-13 2 80 .. 395 471 .. 394 472 .. 0.94 4 ! 61.7 0.1 3.3e-20 9.4e-17 3 81 .] 546 622 .. 544 622 .. 0.94 5 ! 53.4 0.3 1.2e-17 3.5e-14 3 80 .. 651 726 .. 649 727 .. 0.91 6 ! 58.8 0.0 2.5e-19 7.1e-16 4 81 .] 783 858 .. 780 858 .. 0.95 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 3.1 PDZ 38 aeaggLkaGDrIlsv...Ngq 55 a++ + +GD+++ v Ng+ FUN_000387-T1 4 AATV-IGEGDKLINVvllNGE 23 4444.899****998666665 PP == domain 2 score: -3.9 bits; conditional E-value: 9 PDZ 6 kegrgglGfslkg 18 k+g+ +lG+s++g FUN_000387-T1 232 KRGGFSLGISVRG 244 4488899999987 PP == domain 3 score: 50.0 bits; conditional E-value: 1.4e-16 PDZ 2 vslekegrgglGfslkggsdksdkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 v+l+k +g+lG+++ gg + + gi+v+ + p g+a +g +++GDrIl++Ng ++e ls eav+ l+ + + t++i FUN_000387-T1 395 VQLQK-VEGSLGLNIIGGIELG--GIYVKTMAPEGPASLSGkINIGDRILEINGHSLEGLSRQEAVNILRTAPYVCTMLI 471 57778.89************96..**********************************************9998888877 PP == domain 4 score: 61.7 bits; conditional E-value: 3.3e-20 PDZ 3 slekegrgglGfslkggsdksdkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLtil 81 ++k +g++G+++ gg + + gi+v+++lpggaaea+g ++ GDrI+++Ng+ +e l+ +av++l++s + tL+i+ FUN_000387-T1 546 EIPK-LNGSFGLNVTGGPELD--GIYVKSLLPGGAAEASGkIRNGDRIVEINGVAMEGLNRKQAVELLRRSAATATLVIE 622 5666.89************95..************************************************999999985 PP == domain 5 score: 53.4 bits; conditional E-value: 1.2e-17 PDZ 3 slekegrgglGfslkggsdksdkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 l+k +++Gfs++gg d + gifv+ ++p+gaa+ +g + + DrI++vNg++++ + eav+al++s +L++ FUN_000387-T1 651 ELQK-MDHSFGFSVVGGPDFG--GIFVKTINPDGAAAMDGrIGISDRIVAVNGVNLTGATRQEAVDALRNSPIIAQLVV 726 5666.789************7..***********************************************986666665 PP == domain 6 score: 58.8 bits; conditional E-value: 2.5e-19 PDZ 4 lekegrgglGfslkggsdksdkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLtil 81 l k g++glG+sl gg++++ +i++++++pgg+a +g L+++D+Il+vN+++v +s ++ l+++ ++v+L+++ FUN_000387-T1 783 LTK-GQSGLGMSLTGGDSAG--PIYIKKLVPGGSALLSGqLQVNDVILQVNNKNVDRMSYRDVLSILRNCPSEVKLLVQ 858 566.9*************96..******************************************************996 PP >> FERM_M FERM central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 112.2 2.7 8.3e-36 2.4e-32 5 114 .. 111 220 .. 107 222 .. 0.98 Alignments for each domain: == domain 1 score: 112.2 bits; conditional E-value: 8.3e-36 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FERM_M 5 klqdevtrellYlQlkrdllegrlpcseeeallLAaLqlqaelgdyssesheseylslesflpkqllkklkskelekrvleahkklrglsaeeAkl 100 +lq+++tr+l+YlQl++d+leg +++ ee+a+lLA+++lqae+gdy+++ h s+y+ e++lp++ + kl+++ ++k++ hk++ gls ++A++ FUN_000387-T1 111 LLQQQSTRHLYYLQLRKDVLEGGIYVHEETAMLLASYALQAEVGDYNQNVHGSDYFVPEHYLPQRAIAKLTASSIKKQLPSMHKTHTGLSDAQAEI 206 689********************************************************************************************* PP xxxxxxxxxxxxxx RF FERM_M 101 kylqiaqslptyGv 114 +yl++aq+l++yG+ FUN_000387-T1 207 EYLKEAQKLQEYGI 220 *************8 PP >> PDZ_6 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.0 1.1e-09 3.1e-06 2 47 .. 419 467 .. 418 472 .. 0.87 2 ! 32.1 0.1 3.5e-11 1e-07 2 54 .] 569 623 .. 568 623 .. 0.91 3 ! 16.9 0.3 1.9e-06 0.0053 1 43 [. 673 718 .. 673 722 .. 0.91 4 ! 31.8 0.0 4.3e-11 1.2e-07 2 54 .] 805 859 .. 804 859 .. 0.87 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 1.1e-09 PDZ_6 2 vtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllqgagges 47 v+++ p++PA G + GD+Il++NG ++ s ++++ +l+ a+ + FUN_000387-T1 419 VKTMAPEGPASLSGkINIGDRILEINGHSLegLSRQEAVNILRTAPYVC 467 8899**************************999999*******665444 PP == domain 2 score: 32.1 bits; conditional E-value: 3.5e-11 PDZ_6 2 vtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllqgaggesvrllvrR 54 v++ pg+ Ae G +r GD+I+++NG+ + +++++ll+ +l+++R FUN_000387-T1 569 VKSLLPGGAAEASGkIRNGDRIVEINGVAMegLNRKQAVELLR-RSAATATLVIER 623 88899*************************999999*******.888888888877 PP == domain 3 score: 16.9 bits; conditional E-value: 1.9e-06 PDZ_6 1 vvtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllqga 43 +v++++p++ A+ G + D+I++vNG+++ + ++++++l+++ FUN_000387-T1 673 FVKTINPDGAAAMDGrIGISDRIVAVNGVNLtgATRQEAVDALRNS 718 58999*************************9899999******954 PP == domain 4 score: 31.8 bits; conditional E-value: 4.3e-11 PDZ_6 2 vtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllqgaggesvrllvrR 54 ++ vpg+ A G l+v+D+Il+vN+++v +s+ dv +l+ + +++v llv+R FUN_000387-T1 805 IKKLVPGGSALLSGqLQVNDVILQVNNKNVdrMSYRDVLSILR-NCPSEVKLLVQR 859 67789*************************888888*******.666667777766 PP >> PDZ_2 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 3.8e-06 0.011 12 47 .. 402 451 .. 392 462 .. 0.79 2 ! 15.1 0.0 1e-05 0.028 12 63 .. 565 619 .. 533 630 .. 0.76 3 ! 10.5 0.1 0.00028 0.8 12 55 .. 666 716 .. 647 726 .. 0.78 4 ! 11.0 0.0 0.00019 0.55 3 69 .. 790 859 .. 788 866 .. 0.68 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 3.8e-06 PDZ_2 12 d.............gvvVvnVksssPaakag.lkagDvIlsidgkkvksl 47 + g++V ++++Pa +g + +gD+Il+i+g+ ++ l FUN_000387-T1 402 GslglniiggielgGIYVKTMAPEGPASLSGkINIGDRILEINGHSLEGL 451 455555555555669*****************************988655 PP == domain 2 score: 15.1 bits; conditional E-value: 1e-05 PDZ_2 12 dgvvVvnVksssPaakag.lkagDvIlsidgkkvkslt..dleeallkkkpgdtv 63 dg++V + +++ a+++g ++ gD+I++i+g + + l + +e+l ++ + t+ FUN_000387-T1 565 DGIYVKSLLPGGAAEASGkIRNGDRIVEINGVAMEGLNrkQAVELLRRSAATATL 619 499*****************************99655400444444444444444 PP == domain 3 score: 10.5 bits; conditional E-value: 0.00028 PDZ_2 12 d....gvvVvnVksssPaakag.lkagDvIlsidgkkv..ksltdleeall 55 + g+ V +++++ aa g + + D+I++++g + +++++ ++al FUN_000387-T1 666 GpdfgGIFVKTINPDGAAAMDGrIGISDRIVAVNGVNLtgATRQEAVDALR 716 14466999***************************9996666777766665 PP == domain 4 score: 11.0 bits; conditional E-value: 0.00019 PDZ_2 3 lGisfedled..gvvVvnVksssPaakag.lkagDvIlsidgkkvksltdleeall.kkkpgdtvklqvlR 69 lG+s++ ++ +++ + +++ a +g l+++DvIl++++k v++ + +++l+ ++vkl v+R FUN_000387-T1 790 LGMSLTGGDSagPIYIKKLVPGGSALLSGqLQVNDVILQVNNKNVDRM-SYRDVLSiLRNCPSEVKLLVQR 859 566666555555688888888888888888***************643.3344444333445666666666 PP >> FERM_N FERM N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.3 0.1 4.6e-18 1.3e-14 1 62 [. 17 77 .. 17 78 .. 0.97 2 ? -2.5 0.0 2.5 7e+03 44 61 .. 201 218 .. 199 219 .. 0.81 Alignments for each domain: == domain 1 score: 54.3 bits; conditional E-value: 4.6e-18 FERM_N 1 VrlLDgtklefevqkkatgqelLdqVckhlnlkEkdyFGLqfldsksehrWLdlekklekqa 62 V+lL+g++l+++vq +atgq+l + +++hl+l+E+++FGL ++++ eh++Ld + kl+k a FUN_000387-T1 17 VVLLNGERLNVRVQASATGQDLYNIITDHLGLTETTFFGLMIIKDG-EHEFLDFNEKLSKLA 77 89********************************************.************986 PP == domain 2 score: -2.5 bits; conditional E-value: 2.5 FERM_N 44 dsksehrWLdlekklekq 61 d ++e ++L+ ++kl+++ FUN_000387-T1 201 DAQAEIEYLKEAQKLQEY 218 5567889********987 PP >> FERM_C FERM C-terminal PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.3 0.1 1.4e-17 3.9e-14 6 88 .. 235 316 .. 230 320 .. 0.91 Alignments for each domain: == domain 1 score: 53.3 bits; conditional E-value: 1.4e-17 FERM_C 6 ellLGvsakGilvyekkdki..pknlFpWseirkisfkrkkfliklrkeedkkkeetleFklessrackslwklcveqhkffrlr 88 +LG+s +G++vye++ + p+ ++pW++i+++ f+r++f+i+ + +++++++++ ++ s++++++l+k+c + kf + + FUN_000387-T1 235 GFSLGISVRGLIVYEERGIVksPTFRHPWQNIKRMAFHRRRFYIEAH---GDPETSKMVLYTCSYKKSRYLLKMCTSFYKFQMMM 316 578***********99998888999**********************...99999999********************9998765 PP >> SNX17-27-31_F1_FERM Sortin nexin 17/27/31, FERM domain, F1 lobe # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 2e-06 0.0056 3 60 .. 15 70 .. 13 84 .. 0.87 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 2e-06 SNX17-27-31_F1_FERM 3 ldvylmngkkikvkvsstdqtedvLekvakkielpeelvkYFgLFlvkkeeegklsvv 60 ++v l+ng++++v+v+ + + +d+ + ++++++l+e + +FgL ++k+ e++ l + FUN_000387-T1 15 INVVLLNGERLNVRVQASATGQDLYNIITDHLGLTE--TTFFGLMIIKDGEHEFLDFN 70 68********************************98..579*******9988766554 PP >> DUF6288 Family of unknown function (DUF6288) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0018 5 3 42 .. 417 455 .. 416 464 .. 0.80 2 ? 0.3 0.0 0.15 4.3e+02 11 36 .. 575 602 .. 566 626 .. 0.73 3 ! 4.6 0.0 0.0072 20 5 36 .. 805 838 .. 802 847 .. 0.76 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0018 DUF6288 3 ikvtkveegSPAd..Gklkvgdvilgvngktlkkfskdpria 42 i v++++ + PA Gk++ gd il +ng++l+ r++ FUN_000387-T1 417 IYVKTMAPEGPASlsGKINIGDRILEINGHSLE---GLSRQE 455 77999*******999***************666...444444 PP == domain 2 score: 0.3 bits; conditional E-value: 0.15 DUF6288 11 gSPAd..Gklkvgdvilgvngktlkkfs 36 g A+ Gk++ gd i+ +ng+ ++ ++ FUN_000387-T1 575 GGAAEasGKIRNGDRIVEINGVAMEGLN 602 5555555***************666433 PP == domain 3 score: 4.6 bits; conditional E-value: 0.0072 DUF6288 5 vtkveegSPAd..Gklkvgdvilgvngktlkkfs 36 ++k+ g A G+l+v+dvil vn k+++++s FUN_000387-T1 805 IKKLVPGGSALlsGQLQVNDVILQVNNKNVDRMS 838 5665566556556***************887555 PP >> RA_2 RA like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00016 0.45 5 51 .. 15 61 .. 12 75 .. 0.89 2 ? -3.5 0.0 5.8 1.7e+04 59 90 .. 194 222 .. 187 224 .. 0.70 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00016 RA_2 5 vkvflmDgsskavevdsattarevceklaeklglkdsegFsLyeslp 51 ++v l +g+ +v v++++t +++ + + + lgl+++ F+L++ + FUN_000387-T1 15 INVVLLNGERLNVRVQASATGQDLYNIITDHLGLTETTFFGLMIIKD 61 7899*********************************99***98765 PP == domain 2 score: -3.5 bits; conditional E-value: 5.8 RA_2 59 edhehvaDvlskweqyaesgekeekaewklyf 90 + h+ + D++++ e + e+++ +e+ ++f FUN_000387-T1 194 KTHTGLSDAQAEIEYLK---EAQKLQEYGIIF 222 67888999999999976...555555566666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (894 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 614 (0.024036); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.40u 0.54s 00:00:00.94 Elapsed: 00:00:00.51 # Mc/sec: 7114.86 // Query: FUN_000388-T1 [L=69] Description: FUN_000388 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (69 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 286 (0.0111959); expected 510.9 (0.02) Passed bias filter: 239 (0.00935604); expected 510.9 (0.02) Passed Vit filter: 12 (0.000469759); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.35s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 718.74 // Query: FUN_000389-T1 [L=113] Description: FUN_000389 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 383 (0.0149931); expected 510.9 (0.02) Passed bias filter: 356 (0.0139362); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.50 # Mc/sec: 904.58 // Query: FUN_000390-T1 [L=500] Description: FUN_000390 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0031 18.1 0.4 0.019 15.6 0.0 2.3 2 End3 Actin cytoskeleton-regulatory complex protein END3 Domain annotation for each model (and alignments): >> End3 Actin cytoskeleton-regulatory complex protein END3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 7.5e-07 0.019 15 80 .. 273 345 .. 260 352 .. 0.84 2 ? -0.8 0.2 0.089 2.3e+03 72 90 .. 405 423 .. 370 441 .. 0.55 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.5e-07 End3 15 E..evrLkreLaeLeeklekveeeaekr.....esnreessksalvkreleqLLkYKeeqlreleegegkske 80 ev++ r +ae e+ +++++ea+ + ++n++++s ++vk +L +YK e l+++++++ k+++ FUN_000390-T1 273 GdiEVKISRSMAEVEDVCSDMSSEASFSsnsslSENDNADSSLQTVKPISGELGNYKSESLTNASSNTAKASR 345 3347******************999877778887788889999*********************999988765 PP == domain 2 score: -0.8 bits; conditional E-value: 0.089 End3 72 eegegkskeknlksvkeDi 90 +eg++k+k++ l++++ + FUN_000390-T1 405 SEGKNKTKKERLEELSTAL 423 2222222223344433333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (500 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1112 (0.043531); expected 510.9 (0.02) Passed bias filter: 694 (0.0271677); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.36s 00:00:00.73 Elapsed: 00:00:00.53 # Mc/sec: 3826.73 // Query: FUN_000391-T1 [L=489] Description: FUN_000391 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.025 15.4 0.1 0.088 13.6 0.1 2.0 1 Flagellin_C Bacterial flagellin C-terminal helical region 0.032 14.6 0.8 0.091 13.1 0.8 1.8 1 LURAP Leucine rich adaptor protein 0.71 11.2 9.1 4.2 8.7 2.1 3.9 4 Occludin_ELL Occludin homology domain 0.78 10.6 5.4 0.35 11.7 1.5 2.5 2 Spectrin_7 Animal spectrin repeats 2.3 9.2 12.3 1.7 9.6 4.0 2.9 2 APG6_N Apg6 coiled-coil region Domain annotation for each model (and alignments): >> Flagellin_C Bacterial flagellin C-terminal helical region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 1.7e-05 0.088 1 59 [. 417 475 .. 417 485 .. 0.93 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.7e-05 Flagellin_C 1 ldaideaitqldkerssLGavqsRlesavnnlnaqqknlkaaesriedvDmaeestrln 59 ++ i+ea + + +e ++L a + + + +++a + n+k ++s i+d+D + e ++ FUN_000391-T1 417 IQQIEEAFEWIRQELTELRAQDKDIMRTFARIQAEIRNIKHQRSLINDMDETYEYQHME 475 6889**********************************************999988886 PP >> LURAP Leucine rich adaptor protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.8 1.8e-05 0.091 8 54 .. 411 457 .. 402 468 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 1.8e-05 LURAP 8 rskssdlkrledkllalrlelaylraidvkllqqllsinegiesirW 54 ++++ +++e+ + +r+el+ lra d +++ + i+ i i+ FUN_000391-T1 411 KTEKERIQQIEEAFEWIRQELTELRAQDKDIMRTFARIQAEIRNIKH 457 4445567789999**************************99999984 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.1 0.1 5.3e+02 43 87 .. 46 91 .. 24 95 .. 0.65 2 ? -1.9 0.1 1.6 8.2e+03 33 45 .. 336 348 .. 323 364 .. 0.56 3 ? 8.5 0.1 0.00097 4.9 33 94 .. 374 436 .. 369 437 .. 0.85 4 ? 8.7 2.1 0.00083 4.2 29 75 .. 415 461 .. 408 478 .. 0.70 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.1 Occludin_ELL 43 eelkslkegsk.eykkiaeeilqeykklkkdpeylekkkrceyLke 87 +++k ++ +++ ++ ++++ i + + +kd+ +++k+r++ L+e FUN_000391-T1 46 SKWKCSRAERRtRFVSVISDISYSNVRSRKDQIRQARKNRFHALQE 91 4444444333347777888877777777889999999999999987 PP == domain 2 score: -1.9 bits; conditional E-value: 1.6 Occludin_ELL 33 avskkfskleeel 45 ++ ++f+kl++ FUN_000391-T1 336 ELVEEFKKLKKVS 348 3333444444433 PP == domain 3 score: 8.5 bits; conditional E-value: 0.00097 Occludin_ELL 33 avskkfskleeelkslkegsk..eykkiaeeilqeykklkkdpeylekkkrceyLkekLshiKk 94 a ++fs+l+++++ lk +s+ k++ e+i + +k ++++ ++ + +e ++++L+ ++ FUN_000391-T1 374 APLRRFSDLDDSIDGLKGNSSrtTAKTLLESIAKASEKT-EKERIQQIEEAFEWIRQELTELRA 436 55689*************999878888999977776666.88999**************98875 PP == domain 4 score: 8.7 bits; conditional E-value: 0.00083 Occludin_ELL 29 aeleavskkfskleeelkslkegskeykkiaeeilqeykklkkdpey 75 ++++++++ f+ +++el++l+ ++k + ++ ++i+ e++++k++++ FUN_000391-T1 415 ERIQQIEEAFEWIRQELTELRAQDKDIMRTFARIQAEIRNIKHQRSL 461 56778888888888888888888888888888888888887775543 PP >> Spectrin_7 Animal spectrin repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.1 4.8 2.4e+04 5 15 .. 336 346 .. 323 359 .. 0.57 2 ? 11.7 1.5 6.8e-05 0.35 13 69 .. 401 458 .. 395 468 .. 0.81 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 4.8 Spectrin_7 5 eLessfdsLee 15 eL ++f++L++ FUN_000391-T1 336 ELVEEFKKLKK 346 33333333333 PP == domain 2 score: 11.7 bits; conditional E-value: 6.8e-05 Spectrin_7 13 LeellkserdflnekalqqleevwesiqetykqlknqgkkFlseakkvs.eDpyLdvk 69 L e++ + +++++++++qq+ee +e i++ +++l+ q k + +++ e ++ + + FUN_000391-T1 401 LLESIAKASEKTEKERIQQIEEAFEWIRQELTELRAQDKDIMRTFARIQaEIRNIKHQ 458 5566667778889************************998888877777666665555 PP >> APG6_N Apg6 coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 1.3 0.03 1.5e+02 72 99 .. 330 357 .. 305 372 .. 0.67 2 ? 9.6 4.0 0.00033 1.7 36 103 .. 406 465 .. 383 478 .. 0.62 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.03 APG6_N 72 lekekeeldaelealeeelealdeeeee 99 +e+e++el +e ++l++ + +ld++ e FUN_000391-T1 330 TEEERDELVEEFKKLKKVSLELDKDDIE 357 5666666666666666666666666555 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00033 APG6_N 36 ekekeseekeeeleelekeleklekeeeelleeLeelekekeeldaelealeeelealdeeeeefwre 103 k ++++ +++++++e++ e +eL+el ++++++ + +++++e ++++++ FUN_000391-T1 406 AK--------ASEKTEKERIQQIEEAFEWIRQELTELRAQDKDIMRTFARIQAEIRNIKHQRSLINDM 465 22........3334445557777777777777777777777777777777777777777765544444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (489 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2213 (0.0866314); expected 510.9 (0.02) Passed bias filter: 901 (0.0352711); expected 510.9 (0.02) Passed Vit filter: 88 (0.0034449); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.36u 0.41s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 4751.75 // Query: FUN_000392-T1 [L=530] Description: FUN_000392 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-35 118.3 18.6 1.1e-05 25.5 0.0 9.5 9 LRR_6 Leucine Rich repeat 5e-12 44.0 0.0 10 7.3 0.0 8.1 8 LRR_1 Leucine Rich Repeat 1.4e-10 41.8 2.2 4e-10 40.4 2.2 1.8 1 EF-hand_7 EF-hand domain pair 5.3e-08 32.4 3.2 0.00059 19.9 0.3 3.0 2 EF-hand_6 EF-hand domain 7.6e-08 31.9 2.3 0.0034 17.3 0.4 3.0 2 EF-hand_1 EF hand domain 1.3e-05 25.0 4.5 0.092 12.8 0.1 2.9 2 EF-hand_5 EF hand 4.4e-05 24.8 0.2 0.00046 21.5 0.1 2.5 3 EF-hand_11 EF-hand domain 0.00018 22.1 7.2 0.3 11.9 0.3 5.1 6 LRR_4 Leucine Rich repeats (2 copies) 0.00043 20.5 11.0 1.4 9.2 0.3 5.2 4 LRR_8 Leucine rich repeat 0.0066 16.6 2.4 0.26 11.4 0.4 3.3 4 LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain ------ inclusion threshold ------ 0.024 14.9 2.9 0.025 14.8 1.0 2.1 2 EF-hand_8 EF-hand domain pair 0.15 12.5 0.2 0.34 11.3 0.2 1.6 1 EH EH domain 0.15 13.2 0.2 37 5.7 0.0 3.5 3 LRR_2 Leucine Rich Repeat Domain annotation for each model (and alignments): >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.0 0.0076 15 8 24 .] 137 153 .. 135 153 .. 0.92 2 ! 9.0 0.1 0.0011 2.2 2 19 .. 159 176 .. 158 181 .. 0.88 3 ! 8.4 0.0 0.0018 3.6 2 24 .] 187 209 .. 186 209 .. 0.88 4 ! 19.0 0.1 7.2e-07 0.0014 2 24 .] 215 237 .. 214 237 .. 0.97 5 ! 7.4 0.0 0.0036 7.2 2 21 .. 243 262 .. 242 265 .. 0.81 6 ! 13.5 0.1 4.3e-05 0.084 5 23 .. 274 292 .. 270 293 .. 0.90 7 ! 25.5 0.0 5.7e-09 1.1e-05 1 23 [. 298 320 .. 298 321 .. 0.94 8 ! 21.8 0.2 8.8e-08 0.00017 2 24 .] 327 349 .. 326 349 .. 0.96 9 ! 12.5 0.1 8.5e-05 0.17 2 23 .. 355 376 .. 355 377 .. 0.93 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0076 LRR_6 8 LdLsgNdIgDeGleaLa 24 d+ ++++g++G+ a+a FUN_000392-T1 137 IDIKHHGLGPTGARAIA 153 699*************8 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0011 LRR_6 2 nttLteLdLsgNdIgDeG 19 ntt t+L+L+++ +g eG FUN_000392-T1 159 NTTTTTLNLQDCAVGSEG 176 67779************9 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0018 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n ++ eLdL+ N+++ +G+ a+a FUN_000392-T1 187 NFYIIELDLAQNKLSSTGAHAMA 209 777889************98876 PP == domain 4 score: 19.0 bits; conditional E-value: 7.2e-07 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n+tL++++Ls+N++ D+ +e+La FUN_000392-T1 215 NNTLKKVNLSWNEFKDKDAECLA 237 9********************98 PP == domain 5 score: 7.4 bits; conditional E-value: 0.0036 LRR_6 2 nttLteLdLsgNdIgDeGle 21 n+++t LdLs+N++ e ++ FUN_000392-T1 243 NQSITWLDLSHNEFAEEAGM 262 999*********98766665 PP == domain 6 score: 13.5 bits; conditional E-value: 4.3e-05 LRR_6 5 LteLdLsgNdIgDeGleaL 23 L++L+L++N++ + G++a+ FUN_000392-T1 274 LEYLNLGWNHLRGRGGVAI 292 9*****************9 PP == domain 7 score: 25.5 bits; conditional E-value: 5.7e-09 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +n++L++Ld+s+N++ DeG+ a+ FUN_000392-T1 298 ANCSLKTLDISWNGLADEGAAAF 320 59******************998 PP == domain 8 score: 21.8 bits; conditional E-value: 8.8e-08 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n+tLt LdL++N+I+ G+ a+a FUN_000392-T1 327 NNTLTDLDLTNNRITTQGALAFA 349 9********************98 PP == domain 9 score: 12.5 bits; conditional E-value: 8.5e-05 LRR_6 2 nttLteLdLsgNdIgDeGleaL 23 n+tL++L ++ N I+++G+ L FUN_000392-T1 355 NNTLKVLRIGLNPIQNTGAFGL 376 99****************9766 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.6 3.1e+03 3 14 .. 163 174 .. 161 183 .. 0.74 2 ? 3.0 0.0 0.14 2.8e+02 3 15 .. 191 203 .. 189 209 .. 0.80 3 ? 3.9 0.0 0.072 1.4e+02 2 20 .. 218 236 .. 217 238 .. 0.82 4 ? 5.4 0.0 0.024 46 1 13 [. 245 257 .. 245 266 .. 0.82 5 ? 5.4 0.0 0.023 44 2 15 .. 274 287 .. 273 294 .. 0.81 6 ! 6.6 0.0 0.0087 17 1 20 [. 301 320 .. 301 322 .. 0.80 7 ! 7.3 0.0 0.0053 10 2 19 .. 330 347 .. 329 350 .. 0.80 8 ? -1.8 0.0 5.8 1.1e+04 2 13 .. 358 369 .. 357 376 .. 0.79 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.6 LRR_1 3 eeLdLsnNnlsg 14 ++L+L+++ ++ FUN_000392-T1 163 TTLNLQDCAVGS 174 79******8754 PP == domain 2 score: 3.0 bits; conditional E-value: 0.14 LRR_1 3 eeLdLsnNnlsgl 15 eLdL+ N+ls++ FUN_000392-T1 191 IELDLAQNKLSST 203 68********865 PP == domain 3 score: 3.9 bits; conditional E-value: 0.072 LRR_1 2 LeeLdLsnNnlsgllpesl 20 L++++Ls N + +++ e+l FUN_000392-T1 218 LKKVNLSWNEFKDKDAECL 236 99*********88777665 PP == domain 4 score: 5.4 bits; conditional E-value: 0.024 LRR_1 1 nLeeLdLsnNnls 13 ++++LdLs+N + FUN_000392-T1 245 SITWLDLSHNEFA 257 5799******994 PP == domain 5 score: 5.4 bits; conditional E-value: 0.023 LRR_1 2 LeeLdLsnNnlsgl 15 Le+L+L N+l g FUN_000392-T1 274 LEYLNLGWNHLRGR 287 9**********775 PP == domain 6 score: 6.6 bits; conditional E-value: 0.0087 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L++Ld+s N l ++ ++ FUN_000392-T1 301 SLKTLDISWNGLADEGAAAF 320 79*********976666555 PP == domain 7 score: 7.3 bits; conditional E-value: 0.0053 LRR_1 2 LeeLdLsnNnlsgllpes 19 L+ LdL nN+++++ + FUN_000392-T1 330 LTDLDLTNNRITTQGALA 347 899********9776555 PP == domain 8 score: -1.8 bits; conditional E-value: 5.8 LRR_1 2 LeeLdLsnNnls 13 L++L + N++ FUN_000392-T1 358 LKVLRIGLNPIQ 369 999999999995 PP >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.4 2.2 2e-13 4e-10 3 62 .. 458 515 .. 456 516 .. 0.95 Alignments for each domain: == domain 1 score: 40.4 bits; conditional E-value: 2e-13 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEF 62 +l ++F+++D+d++ ++++ee++ l+ ++++p++d+++ +l++++D d+dG i++ EF FUN_000392-T1 458 RLIDLFNQFDKDHSLSVSREEFRLGLK--SIKVPMTDDQLTKLIDMLDNDGDGEIDYGEF 515 7999*******************7777..*****************************99 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.3 3e-07 0.00059 1 28 [. 458 485 .. 458 487 .. 0.92 2 ! 12.0 0.2 9.9e-05 0.19 3 22 .. 496 515 .. 494 518 .. 0.87 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 3e-07 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrs 28 +l ++F++fDkd++ ++s+eE+r l+s FUN_000392-T1 458 RLIDLFNQFDKDHSLSVSREEFRLGLKS 485 5889*******************99987 PP == domain 2 score: 12.0 bits; conditional E-value: 9.9e-05 EF-hand_6 3 reaFklfDkdgdGyisleEl 22 ++ +++D dgdG i++ E+ FUN_000392-T1 496 TKLIDMLDNDGDGEIDYGEF 515 56779*************99 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.1 3.7e-05 0.072 2 28 .. 459 485 .. 458 486 .. 0.91 2 ! 17.3 0.4 1.7e-06 0.0034 3 23 .. 496 516 .. 494 518 .. 0.89 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 3.7e-05 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkk 28 l ++F+ fDkD++ +++eEf+ lk+ FUN_000392-T1 459 LIDLFNQFDKDHSLSVSREEFRLGLKS 485 5689******************99987 PP == domain 2 score: 17.3 bits; conditional E-value: 1.7e-06 EF-hand_1 3 keiFrefDkDgdGkIdfeEfk 23 ++++++D DgdG Id+ Ef FUN_000392-T1 496 TKLIDMLDNDGDGEIDYGEFT 516 5889***************95 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.1 4.7e-05 0.092 1 22 [. 459 480 .. 459 483 .. 0.92 2 ! 12.5 0.9 5.7e-05 0.11 5 21 .. 499 515 .. 496 516 .. 0.89 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 4.7e-05 EF-hand_5 1 lkdtFraiDlNgDGkIskeELk 22 l d+F+++D++++ +s+eE++ FUN_000392-T1 459 LIDLFNQFDKDHSLSVSREEFR 480 6799*****************8 PP == domain 2 score: 12.5 bits; conditional E-value: 5.7e-05 EF-hand_5 5 FraiDlNgDGkIskeEL 21 +++D +gDG+I+ E+ FUN_000392-T1 499 IDMLDNDGDGEIDYGEF 515 689***********998 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 5.1 1e+04 68 84 .. 106 122 .. 91 126 .. 0.81 2 ? -0.8 0.0 1.9 3.8e+03 17 43 .. 203 229 .. 195 235 .. 0.83 3 ! 21.5 0.1 2.3e-07 0.00046 4 78 .. 441 515 .. 438 524 .. 0.89 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 5.1 EF-hand_11 68 nakgrlkyqdflsklsi 84 +a gr y+d s+l i FUN_000392-T1 106 DATGRKAYRDACSQLGI 122 68999999999999876 PP == domain 2 score: -0.8 bits; conditional E-value: 1.9 EF-hand_11 17 shyhaivqefenfdtlksntvsreefr 43 + ha+++ + + +tlk +s +ef+ FUN_000392-T1 203 TGAHAMAEVLTDNNTLKKVNLSWNEFK 229 55689999999999****99**99997 PP == domain 3 score: 21.5 bits; conditional E-value: 2.3e-07 EF-hand_11 4 drdilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqi.ltdeqfdrlwselpvnakgrlkyqdf 78 ++d++ l+k v + + +++ f++fd +s +vsreefr + +++ +td+q+ +l + l + g + y +f FUN_000392-T1 441 NKDLIFVLKKYVEEKNYRLIDLFNQFDKDHSLSVSREEFRLGL-KSIKVpMTDDQLTKLIDMLDNDGDGEIDYGEF 515 7899999*********************************654.5555549**********************998 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 9.8 1.9e+04 4 12 .. 163 171 .. 163 175 .. 0.64 2 ? 3.1 0.1 0.087 1.7e+02 5 30 .. 192 223 .. 190 233 .. 0.68 3 ? 5.1 0.0 0.021 42 2 32 .. 245 280 .. 244 286 .. 0.76 4 ? 0.9 0.0 0.44 8.7e+02 23 31 .. 300 308 .. 292 314 .. 0.61 5 ! 11.9 0.3 0.00015 0.3 2 38 .. 301 342 .. 300 347 .. 0.77 6 ! 11.0 0.7 0.00029 0.56 3 38 .. 330 370 .. 328 376 .. 0.84 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 9.8 LRR_4 4 etLdLsnNr 12 +tL+L+++ FUN_000392-T1 163 TTLNLQDCA 171 467777665 PP == domain 2 score: 3.1 bits; conditional E-value: 0.087 LRR_4 5 tLdLsnNritdidp......lskLpnLetLdL 30 +LdL+ N++++ + l + L++++L FUN_000392-T1 192 ELDLAQNKLSSTGAhamaevLTDNNTLKKVNL 223 89999999999887554333334555777777 PP == domain 3 score: 5.1 bits; conditional E-value: 0.021 LRR_4 2 nLetLdLsnNritdidp..ls....kLpnLetLdLsg 32 + + LdLs+N + + l+ Le+L+L g FUN_000392-T1 245 SITWLDLSHNEFAEEAGmlLGpaidANSGLEYLNL-G 280 6789********97666774466746999*****9.4 PP == domain 4 score: 0.9 bits; conditional E-value: 0.44 LRR_4 23 pnLetLdLs 31 +L+tLd+s FUN_000392-T1 300 CSLKTLDIS 308 566666662 PP == domain 5 score: 11.9 bits; conditional E-value: 0.00015 LRR_4 2 nLetLdLs.nNritdidp..ls.kLpn...LetLdLsgNnkitd 38 +L+tLd+s n + d + ++ +L+ L+ LdL Nn+it+ FUN_000392-T1 301 SLKTLDISwN-GLADEGAaaFGeSLKEnntLTDLDL-TNNRITT 342 89******55.****999774454555566******.7779986 PP == domain 6 score: 11.0 bits; conditional E-value: 0.00029 LRR_4 3 LetLdLsnNritdidpls.....kLpn.LetLdLsgNnkitd 38 L+ LdL nNrit+ + l+ + n L++L + g n+i++ FUN_000392-T1 330 LTDLDLTNNRITTQGALAfakgmQINNtLKVLRI-GLNPIQN 370 999**********999888899777777999999.8668865 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.1 0.5 0.00078 1.5 6 60 .. 193 255 .. 192 256 .. 0.76 2 ? 3.9 0.4 0.032 63 25 38 .. 272 285 .. 267 312 .. 0.63 3 ! 9.2 0.3 0.00073 1.4 3 40 .. 302 343 .. 300 353 .. 0.66 4 ! 7.4 0.4 0.0027 5.3 2 23 .. 329 350 .. 328 380 .. 0.66 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00078 LRR_8 6 LdLssNrltslddga....FkglsnLkvLdLsnNllttlspgafsg....LpsLrsLdLsgNr 60 LdL N+l+s + +a ++++ Lk +Ls N+ + ++++++ s+++LdLs+N FUN_000392-T1 193 LDLAQNKLSSTGAHAmaevLTDNNTLKKVNLSWNEFKDKDAECLAEgiraNQSITWLDLSHNE 255 7888888888776652222678999*************999987643333899********97 PP == domain 2 score: 3.9 bits; conditional E-value: 0.032 LRR_8 25 snLkvLdLsnNllt 38 s+L++L+L+ N l+ FUN_000392-T1 272 SGLEYLNLGWNHLR 285 66777777777665 PP == domain 3 score: 9.2 bits; conditional E-value: 0.00073 LRR_8 3 LrsLdLssNrltslddgaF....kglsnLkvLdLsnNllttl 40 L++Ld+s N l + + aF k ++ L+ LdL+nN++tt FUN_000392-T1 302 LKTLDISWNGLADEGAAAFgeslKENNTLTDLDLTNNRITTQ 343 666666666666655555522225677899999999999985 PP == domain 4 score: 7.4 bits; conditional E-value: 0.0027 LRR_8 2 nLrsLdLssNrltslddgaFkg 23 +L+ LdL++Nr+t+ + aF + FUN_000392-T1 329 TLTDLDLTNNRITTQGALAFAK 350 5888888888888877777765 PP >> LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.4 0.00013 0.26 41 90 .. 181 231 .. 154 241 .. 0.79 2 ? -0.8 0.0 0.75 1.5e+03 68 90 .. 237 259 .. 232 264 .. 0.78 3 ? -0.7 0.0 0.7 1.4e+03 70 99 .. 267 296 .. 243 314 .. 0.56 4 ? 2.1 0.1 0.095 1.9e+02 72 103 .. 325 356 .. 299 371 .. 0.78 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00013 LRR_NXF1-5 41 lkiieenipeLlsLnlsnnklyk..LdglsdivqkapnlkiLnLsknelkse 90 ++++en+ +++L+l +nkl + + ++++ + +lk++nLs ne k + FUN_000392-T1 181 ARLLKENFY-IIELDLAQNKLSStgAHAMAEVLTDNNTLKKVNLSWNEFKDK 231 466777774.789*******98722589********************9976 PP == domain 2 score: -0.8 bits; conditional E-value: 0.75 LRR_NXF1-5 68 sdivqkapnlkiLnLsknelkse 90 ++ ++ ++ L+Ls+ne +e FUN_000392-T1 237 AEGIRANQSITWLDLSHNEFAEE 259 555667778999******98765 PP == domain 3 score: -0.7 bits; conditional E-value: 0.7 LRR_NXF1-5 70 ivqkapnlkiLnLsknelksereLdkvkgl 99 ++ + l LnL n+l+ + kgl FUN_000392-T1 267 AIDANSGLEYLNLGWNHLRGRGGVAIGKGL 296 344445566666666666665555555555 PP == domain 4 score: 2.1 bits; conditional E-value: 0.095 LRR_NXF1-5 72 qkapnlkiLnLsknelksereLdkvkglklee 103 ++ +l L+L++n++ ++ L kg+++++ FUN_000392-T1 325 KENNTLTDLDLTNNRITTQGALAFAKGMQINN 356 56677888999999999999999999988754 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 5.9 1.2e+04 42 49 .. 223 230 .. 223 230 .. 0.85 2 ? 14.8 1.0 1.3e-05 0.025 4 47 .. 473 515 .. 461 516 .. 0.92 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 5.9 EF-hand_8 42 isfeeFcv 49 +s++eF++ FUN_000392-T1 223 LSWNEFKD 230 79****85 PP == domain 2 score: 14.8 bits; conditional E-value: 1.3e-05 EF-hand_8 4 vItresLkrilalLglqdlsedevdtlfrefDtDgdGkisfeeF 47 +++re+++ l+ ++++ +++d+++ l+ +D DgdG i+ eF FUN_000392-T1 473 SVSREEFRLGLKSIKVP-MTDDQLTKLIDMLDNDGDGEIDYGEF 515 579******99888888.*********************97777 PP >> EH EH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.2 0.00018 0.34 13 63 .. 463 516 .. 450 520 .. 0.70 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00018 EH 13 fsglkpenk.kltgskvapvLknsk..LeqdqLakiWdlaDidddGkLdfeefv 63 f++ + ++ ++ ++ Lk+ k + +dqL k+ d+ D d dG++d ef FUN_000392-T1 463 FNQFDKDHSlSVSREEFRLGLKSIKvpMTDDQLTKLIDMLDNDGDGEIDYGEFT 516 555555555556666666666655522579**********************96 PP >> LRR_2 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.1 0.13 2.6e+02 2 16 .. 218 232 .. 218 235 .. 0.91 2 ? -1.2 0.0 2.9 5.7e+03 5 17 .. 249 261 .. 249 263 .. 0.86 3 ? 5.7 0.0 0.019 37 1 15 [. 301 315 .. 301 318 .. 0.90 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.13 LRR_2 2 LKtLhLdsVvfsded 16 LK L++++f+d d FUN_000392-T1 218 LKKVNLSWNEFKDKD 232 8999*******9987 PP == domain 2 score: -1.2 bits; conditional E-value: 2.9 LRR_2 5 LhLdsVvfsdeds 17 L L++++f+ e++ FUN_000392-T1 249 LDLSHNEFAEEAG 261 89******99976 PP == domain 3 score: 5.7 bits; conditional E-value: 0.019 LRR_2 1 sLKtLhLdsVvfsde 15 sLKtL ++++ +de FUN_000392-T1 301 SLKTLDISWNGLADE 315 8*********99998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (530 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1022 (0.0400078); expected 510.9 (0.02) Passed bias filter: 745 (0.0291642); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.37u 0.36s 00:00:00.73 Elapsed: 00:00:00.45 # Mc/sec: 4789.84 // Query: FUN_000393-T1 [L=362] Description: FUN_000393 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-38 131.8 0.0 4.2e-38 131.4 0.0 1.2 1 Ribosomal_L4 Ribosomal protein L4/L1 family 1.3e-25 89.7 3.5 1.3e-25 89.7 3.5 2.1 2 Ribos_L4_asso_C 60S ribosomal protein L4 C-terminal domain Domain annotation for each model (and alignments): >> Ribosomal_L4 Ribosomal protein L4/L1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 131.4 0.0 3.3e-42 4.2e-38 3 188 .. 22 259 .. 20 261 .. 0.93 Alignments for each domain: == domain 1 score: 131.4 bits; conditional E-value: 3.3e-42 Ribosomal_L4 3 LspkvFgaevredlihrvvvaqlanrrqgtastk.trsevsgggkkpwkQKGtGrARvgsir............splwrgGgvafgpkp.rdysek 84 L p vF a++r+d++ v +++ +nrrq++a +k +++++s++ ++++ G++ AR++++r +++rgG+++ ++k r++++k FUN_000393-T1 22 L-PGVFTAQIRPDVVSFVHTNMAKNRRQPYAVSKyAGHQTSAE--SWGT--GRAVARIPRVRgggthrsgqgafGNMCRGGRMFAPTKIwRRWHRK 112 5.88**************************************5..****..********************************************* PP Ribosomal_L4 85 lnkKvrrlAlksalsakakegklvvvd....dlele............spktkelvellkklgl..........................kkkkvL 138 +n K+rr A++sal+a+ ++++++ d ++ +ktk++v+llk l++ +k++L FUN_000393-T1 113 INVKQRRFAMCSALAATSLPALVMARGhrinD--IPevplvvsnsvesFQKTKAAVKLLKVLNAyvdvekcwaskkmragkgkmrnrrttMRKGPL 206 ***************************75442..33455778888889999**********998899999999999999999999999999***** PP Ribosomal_L4 139 ivteeedenlaksarnlpgvdvvkveglnvydLlkadk....vvitksavekle 188 i+++e d ++ +++rnlpgvd+++v++ln++ L ++ + +++++ a+++l+ FUN_000393-T1 207 IIYNE-DHGVTRAFRNLPGVDLLPVDRLNLLRLCPGGHlgrfCIWSEGAIKRLD 259 ***95.**********************************************97 PP >> Ribos_L4_asso_C 60S ribosomal protein L4 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 0.23 2.9e+03 27 47 .. 186 206 .. 183 207 .. 0.80 2 ! 89.7 3.5 1e-29 1.3e-25 1 74 [. 273 345 .. 273 350 .. 0.91 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.23 Ribos_L4_asso_C 27 vlrpakkekktkravqkkNPL 47 +r+ k++ +++r++ +k PL FUN_000393-T1 186 KMRAGKGKMRNRRTTMRKGPL 206 578888888888889999988 PP == domain 2 score: 89.7 bits; conditional E-value: 1e-29 Ribos_L4_asso_C 1 kgynLPrpkmtnaDltRiinSdEiqsvlrpakkekktkravqkkNPLkNkkvllrLNPYakvlkreallkekkr 74 k++nLP+p+mtn DltR+inS+Eiqsvl+p+ +k+ r ++k+NPLkN++++ +LNPYa +l+++a+ + +++ FUN_000393-T1 273 KDFNLPKPIMTNGDLTRLINSEEIQSVLNPPGPRKTAPR-IRKRNPLKNRELMRKLNPYADTLRQAAKETVEEN 345 79*****************************66666677.*************************998877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 689 (0.026972); expected 510.9 (0.02) Passed bias filter: 492 (0.0192601); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3583.57 // Query: FUN_000394-T1 [L=314] Description: FUN_000394 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-23 82.0 0.0 1.3e-10 41.9 0.0 2.3 2 Anthrone_oxy Anthrone oxygenase ------ inclusion threshold ------ 0.06 14.1 1.0 12 6.7 0.0 3.0 3 CwsA Cell wall synthesis protein CwsA 0.13 12.3 1.2 3 8.0 0.3 2.6 3 2-oxogl_dehyd_N 2-oxoglutarate dehydrogenase N-terminus Domain annotation for each model (and alignments): >> Anthrone_oxy Anthrone oxygenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 0.0 2.5e-13 2.1e-09 1 106 [] 46 146 .. 46 146 .. 0.72 2 ! 41.9 0.0 1.5e-14 1.3e-10 1 105 [. 201 300 .. 201 301 .. 0.85 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 2.5e-13 Anthrone_oxy 1 wallfkrgkavfpalalaaalaylylarrarrsaaarlllaaAallllgivpfTllvmvp.lNnaLaalkeaaekeeaeaaevrelldrWgrlnlv 95 w+++f+r+k ++ +l+ +++ ++ ++++++ +l+ +a++l+ vp+T+++m+p + + + + +++++ e+r+ + +W+ ++ v FUN_000394-T1 46 WRESFDRAKFLMAGTSLLPIVGGIAAFAIDQTKGKPWLI---TAIMLAFNVPYTAIAMKPkVIDPIYDY---EVASKKSPGEIRDTVAKWNSFHKV 135 999*****7777776666666666344344444444444...34555578**********655555555...444556999***9999******** PP Anthrone_oxy 96 Rtvlslaaavl 106 Rtv+ + a ++ FUN_000394-T1 136 RTVVDISALIC 146 ****9999887 PP == domain 2 score: 41.9 bits; conditional E-value: 1.5e-14 Anthrone_oxy 1 wallfkrgkavfpalalaaalaylylarrarrsaaarlllaaAallllgivpfTllvmvplNnaLaalkeaaekeeaeaaevrelldrWgrlnlvR 96 w+++f+r+k++ lal+++++ + ++ +++++ + +l+ ++ ll+ i+p+Tl++++p n ++ +++ ++++++ +re + +W+ +++vR FUN_000394-T1 201 WMESFDRAKVFQSRLALLSIISGAGAC--YCNPKKGLPFLI-GGGLLATIFPYTLFILKP--NSIDPIYDKEITAKKSESVIRETICKWNNYHMVR 291 9*******************9999666..788888888855.8888889***********..6788887667777778888887777********* PP Anthrone_oxy 97 tvlslaaav 105 +++sl +v FUN_000394-T1 292 SFISLPVFV 300 ***997665 PP >> CwsA Cell wall synthesis protein CwsA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.016 1.4e+02 94 117 .. 10 33 .. 4 42 .. 0.81 2 ? 6.7 0.0 0.0014 12 88 118 .. 51 81 .. 35 86 .. 0.82 3 ? 1.2 0.0 0.071 6e+02 93 114 .. 164 185 .. 160 195 .. 0.85 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.016 CwsA 94 iagvavavlaGGavafsivrrssr 117 ++v++ ++aGGa+ + +v + r FUN_000394-T1 10 TSTVGTGIIAGGAIYINVVEHPAR 33 45799***********99987655 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0014 CwsA 88 skrpwviagvavavlaGGavafsivrrssrP 118 + ++++ag + ++GG +af+i + + +P FUN_000394-T1 51 DRAKFLMAGTSLLPIVGGIAAFAIDQTKGKP 81 46679*******************9999888 PP == domain 3 score: 1.2 bits; conditional E-value: 0.071 CwsA 93 viagvavavlaGGavafsivrr 114 v+++v++ v++GGa + +v + FUN_000394-T1 164 VLSTVTAGVFVGGAFYINVVEH 185 7889**********99999875 PP >> 2-oxogl_dehyd_N 2-oxoglutarate dehydrogenase N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.3 0.00035 3 20 37 .. 36 53 .. 36 55 .. 0.88 2 ? 2.2 0.0 0.022 1.8e+02 20 36 .. 191 207 .. 191 209 .. 0.86 3 ? -3.6 0.0 1.4 1.2e+04 23 28 .. 257 262 .. 254 264 .. 0.88 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00035 2-oxogl_dehyd_N 20 lkDPsSVdpsWrayFknl 37 l+D +S + +Wr+ F+ FUN_000394-T1 36 LDDSQSLHRQWRESFDRA 53 689************975 PP == domain 2 score: 2.2 bits; conditional E-value: 0.022 2-oxogl_dehyd_N 20 lkDPsSVdpsWrayFkn 36 l D +S +++W + F+ FUN_000394-T1 191 LSDTESCHQEWMESFDR 207 57999*******99986 PP == domain 3 score: -3.6 bits; conditional E-value: 1.4 2-oxogl_dehyd_N 23 PsSVdp 28 P+S+dp FUN_000394-T1 257 PNSIDP 262 9**997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (314 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 724 (0.0283421); expected 510.9 (0.02) Passed bias filter: 624 (0.0244275); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.92 # Mc/sec: 1378.43 // Query: FUN_000395-T1 [L=173] Description: FUN_000395 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-27 95.9 0.1 3.3e-27 95.5 0.1 1.2 1 HIT HIT domain 1.5e-24 87.1 0.1 1.9e-24 86.8 0.1 1.1 1 DcpS_C Scavenger mRNA decapping enzyme C-term binding ------ inclusion threshold ------ 0.2 11.7 0.6 0.49 10.4 0.6 1.7 1 GDPGP1_N GDPGP1-like, N-terminal domain Domain annotation for each model (and alignments): >> HIT HIT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.5 0.1 3.9e-31 3.3e-27 1 97 [. 70 167 .. 70 168 .. 0.95 Alignments for each domain: == domain 1 score: 95.5 bits; conditional E-value: 3.9e-31 HIT 1 rkeipskvvyeddlvlafldidPkapghvLvipkkhleelhdlt...peelgdllsvakkvakalkkkfkadglrvvinngaeagqeVphlHlHvi 93 rkeip++++ ed+++ af+d++P+ap h+Lvip+k +++l t +lg+ll vak va++ + +g+r+vinng++a q+V+hlH+H++ FUN_000395-T1 70 RKEIPADIIHEDEKAIAFRDVNPVAPKHILVIPRKPITQLATSTeqdIPLLGHLLWVAKSVAEKENL--NDSGYRIVINNGRDAAQSVYHLHIHIL 163 689************************************99888666779*************9998..899************************ PP HIT 94 prre 97 ++r+ FUN_000395-T1 164 GGRQ 167 **98 PP >> DcpS_C Scavenger mRNA decapping enzyme C-term binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 86.8 0.1 2.3e-28 1.9e-24 3 101 .. 64 164 .. 62 170 .. 0.96 Alignments for each domain: == domain 1 score: 86.8 bits; conditional E-value: 2.3e-28 DcpS_C 3 vfnkiakgeepervvyedeefvvfkDikpkaklhllvipkrhikslrdLtkehlelLeemrekakkvieekyke..verdelrlgfhypPsvyhLH 96 +f ki+++e+p ++++ede++++f+D++p a+ h+lvip++ i++l t+++++lL ++ +ak+v+e+++ + ++r +++ g ++ +svyhLH FUN_000395-T1 64 IFSKIIRKEIPADIIHEDEKAIAFRDVNPVAPKHILVIPRKPITQLATSTEQDIPLLGHLLWVAKSVAEKENLNdsGYRIVINNGRDAAQSVYHLH 159 899********************************************************************988999******************* PP DcpS_C 97 lHvis 101 +H+++ FUN_000395-T1 160 IHILG 164 ***97 PP >> GDPGP1_N GDPGP1-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.6 5.8e-05 0.49 93 172 .. 73 162 .. 52 163 .. 0.62 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 5.8e-05 GDPGP1_N 93 lesaplkekskllviiNvsPieygHvLlvPe.vakclpqvltkes.....lelalelale...sanpsfrvgfn.slgafasvnhlhfha 172 ++ + ++e++k + + v+P+ H+L++P+ + +l ++++ l + ++++e ++++ r+ n a sv hlh h+ FUN_000395-T1 73 IPADIIHEDEKAIAFRDVNPVAPKHILVIPRkPITQLATSTEQDIpllghLLWVAKSVAEkenLNDSGYRIVINnGRDAAQSVYHLHIHI 162 455555667777777789************625566666655554111112223333333122456778876651567889999999996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (173 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 466 (0.0182423); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.48 # Mc/sec: 1450.48 // Query: FUN_000396-T1 [L=452] Description: FUN_000396 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-212 704.6 0.0 7.9e-212 704.4 0.0 1.0 1 SBP56 56kDa selenium binding protein (SBP56) 0.00081 19.2 0.0 0.053 13.2 0.0 2.6 3 Lactonase Lactonase, 7-bladed beta-propeller Domain annotation for each model (and alignments): >> SBP56 56kDa selenium binding protein (SBP56) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 704.4 0.0 6.2e-216 7.9e-212 14 453 .] 1 452 [] 1 452 [] 0.99 Alignments for each domain: == domain 1 score: 704.4 bits; conditional E-value: 6.2e-216 SBP56 14 ikapreklayvaalyagtgiekpDylavvdvdpesetyskvvsrvelpnlgdelhhsGWnaCsschedaskerryLilPglrssriyvvdtktdpr 109 +++prekl+y+ ++ya+tg+ekpDyla+vd dp s+tyskv++r+++p gdelhhsGWnaCssch+d++++r++L++P+l s+riy+ d++t+pr FUN_000396-T1 1 MNGPREKLLYLPCIYANTGTEKPDYLATVDADPASPTYSKVIHRLPVPFCGDELHHSGWNACSSCHGDPNQKRNRLVMPSLGSGRIYIFDVETNPR 96 79********************************************************************************************** PP SBP56 110 kpelvkviepeevaektglsaphtvhCladgeilisalgdaeGegkGgillldsetfevkgrWekdrekqklayDfWyqlrknvlisseWgaPkaf 205 +p+++k++epeev ktgl++ ht hCl++gei+isa+g++e e++Gg++lld++tf+vkgrWe++ +++++yDfWyq+r+nv+isseWgaP+ f FUN_000396-T1 97 APSIYKIVEPEEVIDKTGLTFLHTAHCLGSGEIMISAMGNKEYEQEGGFVLLDGKTFDVKGRWETK--PAPMGYDFWYQPRHNVMISSEWGAPSSF 190 ***************************************************************975..679************************* PP SBP56 206 ekGfdledveegkyGkrlhvwdleerkllqtidlgeegllplevrflhdPekaegfvgvaLsssvvrfykeedekweaekvieipakkvegealpe 301 + Gf+++d+++gkyG++lhvwd+++r+++qtidlg g++ple+rflhdP++ +gfvg+aL+ss+vrf+ +ed++w+aekv ++p+kkveg+alpe FUN_000396-T1 191 KAGFNPQDIAAGKYGSQLHVWDWTTRTMKQTIDLGV-GTIPLEIRFLHDPDQPQGFVGCALQSSLVRFFMKEDKTWSAEKVCQVPSKKVEGWALPE 285 **********************************96.67********************************************************* PP SBP56 302 lpglvtDilislDDrflyvsnWlhGdlrqydisdpkkPkltgqvrlGGllake...............eapavkgrkleggPqmlqlslDGkrlyv 382 +pgl+tDi+islDD++ly+snWlhGd+rqydisd+k+Pkl+gqv++GG+++++ ++ +vkg+++eggPqm+q+slDGkrlyv FUN_000396-T1 286 MPGLITDIVISLDDKYLYFSNWLHGDIRQYDISDTKNPKLVGQVFVGGSITSDglvkvvedselseqpKPCYVKGKRVEGGPQMIQVSLDGKRLYV 381 ******************************************************************988999************************ PP SBP56 383 tnsLysswdkqfypelvkkgsvllkidvdtekGglsldknflvdfgkepegparahevrykgGDassDiyi 453 t+sL+s wd+qfyp+l kkgs+ll++d+dt +Ggl+l+++f vdfg+epegpa+ahevry+gGD+ssDi++ FUN_000396-T1 382 TTSLFSVWDNQFYPNLAKKGSMLLQVDIDTVNGGLKLNPDFCVDFGEEPEGPALAHEVRYPGGDCSSDIWL 452 **********************************************************************6 PP >> Lactonase Lactonase, 7-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 2.8 0.0 0.0063 80 153 175 .. 72 94 .. 63 108 .. 0.82 2 ! 13.2 0.0 4.2e-06 0.053 247 290 .. 291 333 .. 240 336 .. 0.84 3 ? -2.1 0.0 0.19 2.4e+03 39 54 .. 367 382 .. 352 389 .. 0.62 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.0063 Lactonase 153 dgkflvvvDLGtDkvrvykldke 175 + + lv++ LG+ ++++++++ + FUN_000396-T1 72 KRNRLVMPSLGSGRIYIFDVETN 94 4578****************876 PP == domain 2 score: 13.2 bits; conditional E-value: 4.2e-06 Lactonase 247 aeirvspdgkflyvSnRghdsiavfavdeaggtltlveevsteg 290 +i +s d+k+ly Sn +h i +++ +++++ +lv++v ++g FUN_000396-T1 291 TDIVISLDDKYLYFSNWLHGDIRQYDI-SDTKNPKLVGQVFVGG 333 69*************************.7888****99998877 PP == domain 3 score: -2.1 bits; conditional E-value: 0.19 Lactonase 39 PsylalskdkktlYav 54 P+ +++s d+k+lY+ FUN_000396-T1 367 PQMIQVSLDGKRLYVT 382 4444444445555443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (452 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 440 (0.0172245); expected 510.9 (0.02) Passed bias filter: 419 (0.0164024); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 4558.60 // Query: FUN_000396-T2 [L=367] Description: FUN_000396 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-163 544.5 0.0 3.3e-163 544.2 0.0 1.0 1 SBP56 56kDa selenium binding protein (SB 0.0015 18.3 0.0 0.061 13.0 0.0 2.1 2 Lactonase Lactonase, 7-bladed beta-propeller ------ inclusion threshold ------ 0.15 11.8 0.0 0.49 10.1 0.0 1.7 1 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 0.25 12.2 0.5 5.3 7.9 0.0 2.7 3 Cytochrome_CBB3 Cytochrome C oxidase, cbb3-type, s Domain annotation for each model (and alignments): >> SBP56 56kDa selenium binding protein (SBP56) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 544.2 0.0 5.1e-167 3.3e-163 1 346 [. 8 350 .. 8 356 .. 0.99 Alignments for each domain: == domain 1 score: 544.2 bits; conditional E-value: 5.1e-167 SBP56 1 lkedPgyasPkeaikapreklayvaalyagtgiekpDylavvdvdpesetyskvvsrvelpnlgdelhhsGWnaCsschedaskerryLilPglrs 96 ++++Pgya+P ea+++prekl+y+ ++ya+tg+ekpDyla+vd dp s+tyskv++r+++p gdelhhsGWnaCssch+d++++r++L++P+l s FUN_000396-T2 8 CHSGPGYATPLEAMNGPREKLLYLPCIYANTGTEKPDYLATVDADPASPTYSKVIHRLPVPFCGDELHHSGWNACSSCHGDPNQKRNRLVMPSLGS 103 689********************************************************************************************* PP SBP56 97 sriyvvdtktdprkpelvkviepeevaektglsaphtvhCladgeilisalgdaeGegkGgillldsetfevkgrWekdrekqklayDfWyqlrkn 192 +riy+ d++t+pr+p+++k++epeev ktgl++ ht hCl++gei+isa+g++e e++Gg++lld++tf+vkgrWe++ +++++yDfWyq+r+n FUN_000396-T2 104 GRIYIFDVETNPRAPSIYKIVEPEEVIDKTGLTFLHTAHCLGSGEIMISAMGNKEYEQEGGFVLLDGKTFDVKGRWETK--PAPMGYDFWYQPRHN 197 ****************************************************************************975..679************ PP SBP56 193 vlisseWgaPkafekGfdledveegkyGkrlhvwdleerkllqtidlgeegllplevrflhdPekaegfvgvaLsssvvrfykeedekweaekvie 288 v+isseWgaP+ f+ Gf+++d+++gkyG++lhvwd+++r+++qtidlg g++ple+rflhdP++ +gfvg+aL+ss+vrf+ +ed++w+aekv + FUN_000396-T2 198 VMISSEWGAPSSFKAGFNPQDIAAGKYGSQLHVWDWTTRTMKQTIDLGV-GTIPLEIRFLHDPDQPQGFVGCALQSSLVRFFMKEDKTWSAEKVCQ 292 ***********************************************96.67******************************************** PP SBP56 289 ipakkvegealpelpglvtDilislDDrflyvsnWlhGdlrqydisdpkkPkltgqvr 346 +p+kkveg+alpe+pgl+tDi+islDD++ly+snWlhGd+rqydisd+k+Pkl+gqv+ FUN_000396-T2 293 VPSKKVEGWALPEMPGLITDIVISLDDKYLYFSNWLHGDIRQYDISDTKNPKLVGQVS 350 ********************************************************96 PP >> Lactonase Lactonase, 7-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.1 0.0 0.0096 62 153 175 .. 92 114 .. 83 128 .. 0.82 2 ! 13.0 0.0 9.5e-06 0.061 247 287 .. 311 350 .. 259 359 .. 0.83 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.0096 Lactonase 153 dgkflvvvDLGtDkvrvykldke 175 + + lv++ LG+ ++++++++ + FUN_000396-T2 92 KRNRLVMPSLGSGRIYIFDVETN 114 4578****************876 PP == domain 2 score: 13.0 bits; conditional E-value: 9.5e-06 Lactonase 247 aeirvspdgkflyvSnRghdsiavfavdeaggtltlveevs 287 +i +s d+k+ly Sn +h i +++ +++++ +lv++vs FUN_000396-T2 311 TDIVISLDDKYLYFSNWLHGDIRQYDI-SDTKNPKLVGQVS 350 69*************************.7788999999887 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 7.6e-05 0.49 19 112 .. 229 342 .. 217 353 .. 0.68 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 7.6e-05 Beta-prop_WDR90_POC16_2nd 19 riWd..ldtlqqlydfsaseeaPcavaf..hPskq..vfacGfssGvvrvfsveatsllaehkqh....r..........gkvt 82 ++Wd + t++q d+ +P + f P ++ + c +s +vr+f e+ + ae+ ++ + g +t FUN_000396-T2 229 HVWDwtTRTMKQTIDLG-VGTIPLEIRFlhDPDQPqgFVGCALQSSLVRFFMKEDKTWSAEKVCQvpskKvegwalpempGLIT 311 56662256789999987.5788999987544665422456888999999998877766666533211111112222222288** PP Beta-prop_WDR90_POC16_2nd 83 glvfspdgeyly.sacslGslalydaseeey 112 +v+s d++yly s +G + +yd+s+++ FUN_000396-T2 312 DIVISLDDKYLYfSNWLHGDIRQYDISDTKN 342 ***********7366789********98775 PP >> Cytochrome_CBB3 Cytochrome C oxidase, cbb3-type, subunit III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 2 1.3e+04 17 28 .. 8 19 .. 6 29 .. 0.58 2 ? 7.9 0.0 0.00083 5.3 13 27 .. 81 101 .. 73 124 .. 0.76 3 ? 1.4 0.0 0.092 5.9e+02 21 49 .. 222 250 .. 218 258 .. 0.86 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 2 Cytochrome_CBB3 17 CHgeggagpsla 28 CH g + +l FUN_000396-T2 8 CHSGPGYATPLE 19 996344444454 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00083 Cytochrome_CBB3 13 nCasCHgeggag......psl 27 +C+sCHg+ +++ psl FUN_000396-T2 81 ACSSCHGDPNQKrnrlvmPSL 101 7******55444345555554 PP == domain 3 score: 1.4 bits; conditional E-value: 0.092 Cytochrome_CBB3 21 ggagpslagralspealvdiirngkgaMp 49 g+ g +l+ ++++++++++i+ g+g p FUN_000396-T2 222 GKYGSQLHVWDWTTRTMKQTIDLGVGTIP 250 4557889999***********99998877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (367 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 451 (0.0176551); expected 510.9 (0.02) Passed bias filter: 408 (0.0159718); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 3558.57 // Query: FUN_000396-T3 [L=419] Description: FUN_000396 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-190 634.1 0.0 2e-190 633.9 0.0 1.0 1 SBP56 56kDa selenium binding protein (SB 0.00068 19.4 0.0 0.047 13.4 0.0 2.6 3 Lactonase Lactonase, 7-bladed beta-propeller ------ inclusion threshold ------ 0.059 13.1 0.0 0.27 10.9 0.0 2.0 2 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller Domain annotation for each model (and alignments): >> SBP56 56kDa selenium binding protein (SBP56) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 633.9 0.0 2.3e-194 2e-190 1 399 [. 8 418 .. 8 419 .] 0.99 Alignments for each domain: == domain 1 score: 633.9 bits; conditional E-value: 2.3e-194 SBP56 1 lkedPgyasPkeaikapreklayvaalyagtgiekpDylavvdvdpesetyskvvsrvelpnlgdelhhsGWnaCsschedaskerryLilPglrs 96 ++++Pgya+P ea+++prekl+y+ ++ya+tg+ekpDyla+vd dp s+tyskv++r+++p gdelhhsGWnaCssch+d++++r++L++P+l s FUN_000396-T3 8 CHSGPGYATPLEAMNGPREKLLYLPCIYANTGTEKPDYLATVDADPASPTYSKVIHRLPVPFCGDELHHSGWNACSSCHGDPNQKRNRLVMPSLGS 103 689********************************************************************************************* PP SBP56 97 sriyvvdtktdprkpelvkviepeevaektglsaphtvhCladgeilisalgdaeGegkGgillldsetfevkgrWekdrekqklayDfWyqlrkn 192 +riy+ d++t+pr+p+++k++epeev ktgl++ ht hCl++gei+isa+g++e e++Gg++lld++tf+vkgrWe++ +++++yDfWyq+r+n FUN_000396-T3 104 GRIYIFDVETNPRAPSIYKIVEPEEVIDKTGLTFLHTAHCLGSGEIMISAMGNKEYEQEGGFVLLDGKTFDVKGRWETK--PAPMGYDFWYQPRHN 197 ****************************************************************************975..679************ PP SBP56 193 vlisseWgaPkafekGfdledveegkyGkrlhvwdleerkllqtidlgeegllplevrflhdPekaegfvgvaLsssvvrfykeedekweaekvie 288 v+isseWgaP+ f+ Gf+++d+++gkyG++lhvwd+++r+++qtidlg g++ple+rflhdP++ +gfvg+aL+ss+vrf+ +ed++w+aekv + FUN_000396-T3 198 VMISSEWGAPSSFKAGFNPQDIAAGKYGSQLHVWDWTTRTMKQTIDLGV-GTIPLEIRFLHDPDQPQGFVGCALQSSLVRFFMKEDKTWSAEKVCQ 292 ***********************************************96.67******************************************** PP SBP56 289 ipakkvegealpelpglvtDilislDDrflyvsnWlhGdlrqydisdpkkPkltgqvrlGGllake...............eapavkgrkleggPq 369 +p+kkveg+alpe+pgl+tDi+islDD++ly+snWlhGd+rqydisd+k+Pkl+gqv++GG+++++ ++ +vkg+++eggPq FUN_000396-T3 293 VPSKKVEGWALPEMPGLITDIVISLDDKYLYFSNWLHGDIRQYDISDTKNPKLVGQVFVGGSITSDglvkvvedselseqpKPCYVKGKRVEGGPQ 388 *******************************************************************************988999*********** PP SBP56 370 mlqlslDGkrlyvtnsLysswdkqfypelv 399 m+q+slDGkrlyvt+sL+s wd+qfyp+l FUN_000396-T3 389 MIQVSLDGKRLYVTTSLFSVWDNQFYPNLA 418 ***************************875 PP >> Lactonase Lactonase, 7-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 2.9 0.0 0.0085 73 153 175 .. 92 114 .. 83 128 .. 0.82 2 ! 13.4 0.0 5.5e-06 0.047 247 290 .. 311 353 .. 259 356 .. 0.84 3 ? -2.2 0.0 0.3 2.5e+03 39 53 .. 387 401 .. 372 405 .. 0.60 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.0085 Lactonase 153 dgkflvvvDLGtDkvrvykldke 175 + + lv++ LG+ ++++++++ + FUN_000396-T3 92 KRNRLVMPSLGSGRIYIFDVETN 114 4578****************876 PP == domain 2 score: 13.4 bits; conditional E-value: 5.5e-06 Lactonase 247 aeirvspdgkflyvSnRghdsiavfavdeaggtltlveevsteg 290 +i +s d+k+ly Sn +h i +++ +++++ +lv++v ++g FUN_000396-T3 311 TDIVISLDDKYLYFSNWLHGDIRQYDI-SDTKNPKLVGQVFVGG 353 69*************************.7888****99998877 PP == domain 3 score: -2.2 bits; conditional E-value: 0.3 Lactonase 39 PsylalskdkktlYa 53 P+ +++s d+k+lY+ FUN_000396-T3 387 PQMIQVSLDGKRLYV 401 444445555555554 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 3.2e-05 0.27 19 129 .. 229 357 .. 217 370 .. 0.65 2 ? -3.3 0.0 0.66 5.6e+03 127 142 .. 384 399 .. 378 408 .. 0.70 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 3.2e-05 Beta-prop_WDR90_POC16_2nd 19 riWd..ldtlqqlydfsaseeaPcavaf..hPskq..vfacGfssGvvrvfsveatsllaehkqh....r..........gkvt 82 ++Wd + t++q d+ +P + f P ++ + c +s +vr+f e+ + ae+ ++ + g +t FUN_000396-T3 229 HVWDwtTRTMKQTIDLG-VGTIPLEIRFlhDPDQPqgFVGCALQSSLVRFFMKEDKTWSAEKVCQvpskKvegwalpempGLIT 311 56662246789999987.5788999887544665422456888999999998877766666533211111112222222289** PP Beta-prop_WDR90_POC16_2nd 83 glvfspdgeyly.sacslGslalydaseeeyevlrvlgnvvardeelg 129 +v+s d++yly s +G + +yd+s+++ +++g+v + ++ ++ FUN_000396-T3 312 DIVISLDDKYLYfSNWLHGDIRQYDISDTKNP--KLVGQVFVGGSITS 357 ***********7366789********998765..45566655555555 PP == domain 2 score: -3.3 bits; conditional E-value: 0.66 Beta-prop_WDR90_POC16_2nd 127 elgpealavsedsrrl 142 e gp+++ vs d++rl FUN_000396-T3 384 EGGPQMIQVSLDGKRL 399 5578888888888877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (419 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 620 (0.0242709); expected 510.9 (0.02) Passed bias filter: 571 (0.0223527); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.45 # Mc/sec: 3773.72 // Query: FUN_000397-T1 [L=1538] Description: FUN_000397 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-18 66.2 0.0 8e-18 65.3 0.0 1.4 1 Pkinase Protein kinase domain 0.0011 18.9 0.0 0.0019 18.0 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase ------ inclusion threshold ------ 0.034 13.9 0.0 0.061 13.0 0.0 1.3 1 Kinase-like Kinase-like Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.3 0.0 9.4e-22 8e-18 95 258 .. 1290 1459 .. 1197 1462 .. 0.82 Alignments for each domain: == domain 1 score: 65.3 bits; conditional E-value: 9.4e-22 Pkinase 95 lseeeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk..........ltsfvgtseYmAPEvl...kskky. 174 e+++ +l q+l+++++lH+e vvHrDlK eN+ + + g l + F +a + ++++ +++ g e ++PE+l ++ FUN_000397-T1 1290 TYEKKICLLLLQLLSAIDHLHREAVVHRDLKAENLCLLDCGLLVVFNFQHALQQAQTTRpspfiiskaaADDLGGNWEHLPPEILtspEEAALl 1383 45667888999************************88889***********99999988999******999999***********887333333 PP Pkinase 175 .gkkvDvWslGvilyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellq 258 + +D +++G+++yell +++pf + ++++dq +p +s++s+ + + ++ll++ p++Rl+a e+lq FUN_000397-T1 1384 nYEGCDTFAAGCLVYELLHRSNPFA--VNRLLIQQDFDQ-------SDLPPIPVKSQFSRGLCIIARQLLRRFPQERLSAGEALQ 1459 5688*********************..344445667777.......4455899****************************9998 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 2.3e-07 0.0019 89 199 .. 1274 1402 .. 1254 1415 .. 0.62 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 2.3e-07 PK_Tyr_Ser-Thr 89 kefLrkk......keklslkellklalqiAkGmeyLeskklvHrdlaarN.vLvsekkvvkisDf..GLardvekddyy.....kkkekaklp 167 fL+++ + + k+++ l lq+ +++++L+++ +vHrdl a N +L++ + f +L ++ +++ +k+ +l FUN_000397-T1 1274 ACFLKRTkeehenDPETYEKKICLLLLQLLSAIDHLHREAVVHRDLKAENlCLLDCGL-LVVFNFqhALQQAQTTR--PspfiiSKAAADDLG 1363 55565555555545666678889999************************55666544.33444411333333222..123444333334443 PP PK_Tyr_Ser-Thr 168 ikW..mapEslkekk.....ftsksDvWsfGvllwEift 199 +W ++pE+l++ + + +D ++ G l++E++ FUN_000397-T1 1364 GNWehLPPEILTSPEeaallNYEGCDTFAAGCLVYELLH 1402 333225666666655555555566777777777777765 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 7.2e-06 0.061 148 198 .. 1296 1346 .. 1266 1419 .. 0.84 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 7.2e-06 Kinase-like 148 lllTlqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtk 198 ll lql+ + +L+ + +vh +++++nl+l g +++ +f++ ++ + FUN_000397-T1 1296 CLLLLQLLSAIDHLHREAVVHRDLKAENLCLLDCGLLVVFNFQHALQQAQT 1346 4678999***********************************986655544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1538 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 981 (0.0384028); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.52u 0.39s 00:00:00.91 Elapsed: 00:00:00.42 # Mc/sec: 14657.59 // Query: FUN_000398-T1 [L=110] Description: FUN_000398 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-23 80.8 0.7 9.8e-23 80.4 0.7 1.2 1 TFIIA_gamma_N Transcription initiation factor IIA, gamma sub 1.5e-22 80.0 2.9 2.5e-22 79.3 2.9 1.4 1 TFIIA_gamma_C Transcription initiation factor IIA, gamma sub Domain annotation for each model (and alignments): >> TFIIA_gamma_N Transcription initiation factor IIA, gamma subunit, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.4 0.7 7.7e-27 9.8e-23 1 47 [] 2 48 .. 2 48 .. 0.98 Alignments for each domain: == domain 1 score: 80.4 bits; conditional E-value: 7.7e-27 TFIIA_gamma_N 1 yyelYRrstlGtaLtdaLDeliqdgkItpqlamkVLeqFDksineaL 47 +y+lYR++tlG++L+++LDeliq+++I+pqla++VL qFDk+in aL FUN_000398-T1 2 SYQLYRNTTLGNSLQESLDELIQTQQISPQLALQVLLQFDKAINYAL 48 6*******************************************987 PP >> TFIIA_gamma_C Transcription initiation factor IIA, gamma subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.3 2.9 1.9e-26 2.5e-22 1 43 [] 59 100 .. 59 100 .. 0.99 Alignments for each domain: == domain 1 score: 79.3 bits; conditional E-value: 1.9e-26 TFIIA_gamma_C 1 KGhLdtYRfcDdVWtFilkdvtfkldnnetvkvdkvKIVACda 43 KGhL+tYRfcD+VWtF+l+dv+f+ e++kvdkvK+VACd+ FUN_000398-T1 59 KGHLNTYRFCDNVWTFVLNDVEFREV-GEIIKVDKVKVVACDG 100 9*************************.**************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 792 (0.0310041); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1099.10 // Query: FUN_000399-T1 [L=167] Description: FUN_000399 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-75 252.7 0.2 1.4e-75 252.5 0.2 1.0 1 Mago_nashi Mago nashi protein Domain annotation for each model (and alignments): >> Mago_nashi Mago nashi protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 252.5 0.2 5.5e-80 1.4e-75 1 142 [] 26 167 .] 26 167 .] 1.00 Alignments for each domain: == domain 1 score: 252.5 bits; conditional E-value: 5.5e-80 Mago_nashi 1 fylryyvghkgkfGheflefefksdgklrYannsnYkndslirkevlvskavleelkriieeseilkeddekWpekdrvgkqeleiklgkehisfe 96 fylryyvghkgkfGheflefef++dgklrYannsnYknd +irke++v+kav++elkrii eseilkedd+ Wp++drvg+qelei++ +ehisf+ FUN_000399-T1 26 FYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAFVHKAVMDELKRIIGESEILKEDDTLWPQPDRVGRQELEIVMADEHISFT 121 9*********************************************************************************************** PP Mago_nashi 97 takigslsdvqeskdpeGlrvfyylvqDlkalvfslislhfkikpi 142 t+kigsl+dv+++kd++Glr+fyylvqDlk++vfsli lhfkikpi FUN_000399-T1 122 TSKIGSLIDVNQCKDADGLRCFYYLVQDLKCMVFSLIGLHFKIKPI 167 ********************************************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 756 (0.0295948); expected 510.9 (0.02) Passed bias filter: 644 (0.0252104); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1651.78 // Query: FUN_000400-T1 [L=689] Description: FUN_000400 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.01 15.8 26.5 37 4.4 0.2 9.1 9 EIF3E_C Eukaryotic translation initiation factor 3 subunit 0.036 15.1 1.0 2.4e+02 2.9 0.0 7.3 12 Phe_ZIP Phenylalanine zipper 1.4 9.3 35.9 11 6.4 0.1 10.8 12 DUF4549 Domain of unknown function (DUF4549) Domain annotation for each model (and alignments): >> EIF3E_C Eukaryotic translation initiation factor 3 subunit E, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 219 228 .. 219 230 .. 0.89 2 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 253 262 .. 253 264 .. 0.89 3 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 287 296 .. 287 298 .. 0.89 4 ? 4.4 0.2 0.0044 37 8 17 .. 321 330 .. 321 332 .. 0.91 5 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 355 364 .. 355 366 .. 0.89 6 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 389 398 .. 389 400 .. 0.89 7 ? 4.4 0.2 0.0044 37 8 17 .. 423 432 .. 423 434 .. 0.91 8 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 457 466 .. 457 468 .. 0.89 9 ? 2.8 0.1 0.015 1.3e+02 8 17 .. 491 500 .. 491 502 .. 0.89 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 219 DKTKSISSKS 228 7******998 PP == domain 2 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 253 DKTKSISSKS 262 7******998 PP == domain 3 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 287 DKTKSISSKS 296 7******998 PP == domain 4 score: 4.4 bits; conditional E-value: 0.0044 EIF3E_C 8 EKTKnLsfRT 17 EKTK++s ++ FUN_000400-T1 321 EKTKSISSKS 330 9******998 PP == domain 5 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 355 DKTKSISSKS 364 7******998 PP == domain 6 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 389 DKTKSISSKS 398 7******998 PP == domain 7 score: 4.4 bits; conditional E-value: 0.0044 EIF3E_C 8 EKTKnLsfRT 17 EKTK++s ++ FUN_000400-T1 423 EKTKSISSKS 432 9******998 PP == domain 8 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 457 DKTKSISSKS 466 7******998 PP == domain 9 score: 2.8 bits; conditional E-value: 0.015 EIF3E_C 8 EKTKnLsfRT 17 +KTK++s ++ FUN_000400-T1 491 DKTKSISSKS 500 7******998 PP >> Phe_ZIP Phenylalanine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 3 2.6e+04 33 49 .. 69 85 .. 65 86 .. 0.76 2 ? 2.9 0.0 0.029 2.4e+02 15 44 .. 165 194 .. 158 196 .. 0.89 3 ? -2.5 0.0 1.3 1.1e+04 15 43 .. 199 227 .. 198 227 .. 0.73 4 ? -1.6 0.0 0.69 5.9e+03 15 43 .. 233 261 .. 229 261 .. 0.78 5 ? -1.2 0.0 0.52 4.4e+03 15 43 .. 267 295 .. 263 295 .. 0.82 6 ? -1.9 0.0 0.85 7.2e+03 15 42 .. 301 328 .. 298 329 .. 0.77 7 ? -1.2 0.0 0.52 4.4e+03 15 43 .. 335 363 .. 331 363 .. 0.82 8 ? -1.2 0.0 0.52 4.4e+03 15 43 .. 369 397 .. 365 397 .. 0.82 9 ? -1.9 0.0 0.85 7.2e+03 15 42 .. 403 430 .. 400 431 .. 0.77 10 ? -1.2 0.0 0.52 4.4e+03 15 43 .. 437 465 .. 433 465 .. 0.82 11 ? -1.2 0.0 0.52 4.4e+03 15 43 .. 471 499 .. 467 499 .. 0.82 12 ? -2.7 0.0 1.5 1.3e+04 16 41 .. 506 531 .. 504 533 .. 0.71 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 3 Phe_ZIP 33 rplaakefsrkFvelFl 49 r+ + ++f r+ ++F FUN_000400-T1 69 RTSTTANFQRRVPDVFK 85 67788999999999886 PP == domain 2 score: 2.9 bits; conditional E-value: 0.029 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrkF 44 sd+A++ + f+s + ++p +ak +s kF FUN_000400-T1 165 SDYARQKRLFMSVEGGRDHPDQAKPVSHKF 194 79*********98888899*****999999 PP == domain 3 score: -2.5 bits; conditional E-value: 1.3 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 sd++++ + f+ e++ p + k++s+k FUN_000400-T1 199 SDYSRQKRLFMDVDEEQEYPDKTKSISSK 227 68899999999555554558888888876 PP == domain 4 score: -1.6 bits; conditional E-value: 0.69 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 s++A++ + ++ + + + p + k++s+k FUN_000400-T1 233 SNYARQKRLYMGNVEKPEYPDKTKSISSK 261 67899******777766668888887765 PP == domain 5 score: -1.2 bits; conditional E-value: 0.52 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 s++A++ + ++ + e + p + k++s+k FUN_000400-T1 267 SNYARQKRLYMGNVEEPEYPDKTKSISSK 295 6799*******888887778888888775 PP == domain 6 score: -1.9 bits; conditional E-value: 0.85 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsr 42 s++A++ + ++ + e + p + k++s+ FUN_000400-T1 301 SNYARQKRLYMGNVEEPEYPEKTKSISS 328 5789999****88777777777777776 PP == domain 7 score: -1.2 bits; conditional E-value: 0.52 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 s++A++ + ++ + e + p + k++s+k FUN_000400-T1 335 SNYARQKRLYMGNVEEPEYPDKTKSISSK 363 6799*******888887778888888775 PP == domain 8 score: -1.2 bits; conditional E-value: 0.52 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 s++A++ + ++ + e + p + k++s+k FUN_000400-T1 369 SNYARQKRLYMGNVEEPEYPDKTKSISSK 397 6799*******888887778888888775 PP == domain 9 score: -1.9 bits; conditional E-value: 0.85 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsr 42 s++A++ + ++ + e + p + k++s+ FUN_000400-T1 403 SNYARQKRLYMGNVEEPEYPEKTKSISS 430 5789999****88777777777777776 PP == domain 10 score: -1.2 bits; conditional E-value: 0.52 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 s++A++ + ++ + e + p + k++s+k FUN_000400-T1 437 SNYARQKRLYMGNVEEPEYPDKTKSISSK 465 6799*******888887778888888775 PP == domain 11 score: -1.2 bits; conditional E-value: 0.52 Phe_ZIP 15 sdfAkafikfvsenpeearplaakefsrk 43 s++A++ + ++ + e + p + k++s+k FUN_000400-T1 471 SNYARQKRLYMGNVEEPEYPDKTKSISSK 499 6799*******888887778888888775 PP == domain 12 score: -2.7 bits; conditional E-value: 1.5 Phe_ZIP 16 dfAkafikfvsenpeearplaakefs 41 ++A++ + ++ + e + p + k +s FUN_000400-T1 506 NYARQKRLYMGNVEEPEYPDKTKPVS 531 78999999*97777666666666555 PP >> DUF4549 Domain of unknown function (DUF4549) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.2 0.0077 66 28 59 .. 109 139 .. 88 172 .. 0.82 2 ? 2.8 0.1 0.016 1.4e+02 31 58 .. 213 240 .. 200 248 .. 0.85 3 ? 0.8 0.1 0.069 5.9e+02 35 58 .. 251 274 .. 244 279 .. 0.88 4 ? 1.4 0.1 0.044 3.8e+02 34 58 .. 284 308 .. 277 316 .. 0.86 5 ? 1.5 0.1 0.04 3.4e+02 34 58 .. 318 342 .. 311 348 .. 0.86 6 ? 1.3 0.1 0.048 4.1e+02 34 58 .. 352 376 .. 346 382 .. 0.86 7 ? 1.4 0.1 0.044 3.8e+02 34 58 .. 386 410 .. 379 418 .. 0.86 8 ? 1.6 0.1 0.039 3.3e+02 34 58 .. 420 444 .. 413 452 .. 0.86 9 ? 1.3 0.1 0.048 4.1e+02 34 58 .. 454 478 .. 448 484 .. 0.86 10 ? 1.3 0.1 0.046 3.9e+02 34 58 .. 488 512 .. 481 518 .. 0.86 11 ? 0.5 0.0 0.082 7e+02 34 58 .. 522 546 .. 513 551 .. 0.86 12 ? 6.4 0.1 0.0012 11 29 61 .. 584 616 .. 563 627 .. 0.86 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.0077 DUF4549 28 ieeaelllGkkakslssvsipkdasyfrrere 59 +ee + ++ +kak++ss s +d +y ++ r FUN_000400-T1 109 VEE-GREYTDKAKPISSKSKDQDSDYSQQKRL 139 444.568899****************999985 PP == domain 2 score: 2.8 bits; conditional E-value: 0.016 DUF4549 31 aelllGkkakslssvsipkdasyfrrer 58 e ++ +k+ks+ss s d +y r+ r FUN_000400-T1 213 EEQEYPDKTKSISSKSEVPDSNYARQKR 240 4668999******************998 PP == domain 3 score: 0.8 bits; conditional E-value: 0.069 DUF4549 35 lGkkakslssvsipkdasyfrrer 58 + +k+ks+ss s d +y r+ r FUN_000400-T1 251 YPDKTKSISSKSEVPDSNYARQKR 274 66899****************998 PP == domain 4 score: 1.4 bits; conditional E-value: 0.044 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 284 EYPDKTKSISSKSEVPDSNYARQKR 308 577899****************998 PP == domain 5 score: 1.5 bits; conditional E-value: 0.04 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 318 EYPEKTKSISSKSEVPDSNYARQKR 342 57789*****************998 PP == domain 6 score: 1.3 bits; conditional E-value: 0.048 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 352 EYPDKTKSISSKSEVPDSNYARQKR 376 577899****************998 PP == domain 7 score: 1.4 bits; conditional E-value: 0.044 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 386 EYPDKTKSISSKSEVPDSNYARQKR 410 577899****************998 PP == domain 8 score: 1.6 bits; conditional E-value: 0.039 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 420 EYPEKTKSISSKSEVPDSNYARQKR 444 57789*****************998 PP == domain 9 score: 1.3 bits; conditional E-value: 0.048 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 454 EYPDKTKSISSKSEVPDSNYARQKR 478 577899****************998 PP == domain 10 score: 1.3 bits; conditional E-value: 0.046 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+ks+ss s d +y r+ r FUN_000400-T1 488 EYPDKTKSISSKSEVPDSNYARQKR 512 577899****************998 PP == domain 11 score: 0.5 bits; conditional E-value: 0.082 DUF4549 34 llGkkakslssvsipkdasyfrrer 58 ++ +k+k++ss s d +y r+ r FUN_000400-T1 522 EYPDKTKPVSSKSEAPDSNYARQKR 546 577899****************998 PP == domain 12 score: 6.4 bits; conditional E-value: 0.0012 DUF4549 29 eeaelllGkkakslssvsipkdasyfrrerelv 61 e+ + ++ +kaks+s s+ +d +y+++er ++ FUN_000400-T1 584 EDEGQEYPDKAKSVSFKSGVQDSDYLQQERMFT 616 67788999**********************876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (689 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 576 (0.0225484); expected 510.9 (0.02) Passed bias filter: 205 (0.00802505); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.37s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 6628.69 // Query: FUN_000401-T1 [L=570] Description: FUN_000401 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-80 269.5 0.4 1.1e-79 269.1 0.4 1.2 1 CHGN Chondroitin N-acetylgalactosaminyltransferas 2.8e-07 30.6 0.3 7e-07 29.3 0.3 1.6 1 Glyco_transf_7C N-terminal domain of galactosyltransferase 7.6e-05 22.8 0.0 0.00046 20.3 0.0 2.1 1 Glyco_tranf_2_2 Glycosyltransferase like family 2 0.0076 16.7 0.0 0.015 15.7 0.0 1.5 1 Glycos_transf_2 Glycosyl transferase family 2 ------ inclusion threshold ------ 0.11 13.2 0.8 0.15 12.7 0.3 1.6 2 PHM7_cyt Cytosolic domain of 10TM putative phosphate 0.19 13.0 3.7 4.6 8.5 0.0 3.0 2 GeBP-like_DBD Glabrous-enhancer-binding protein-like famil 0.29 11.9 6.0 0.79 10.5 6.0 1.8 1 DUF7491 Coiled-coil region of unknown function (DUF7 1.3 9.9 8.6 3.1 8.8 8.6 1.5 1 CC4_CEP85 Centrosomal protein of 85 kDa-like, CC4 coil Domain annotation for each model (and alignments): >> CHGN Chondroitin N-acetylgalactosaminyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 269.1 0.4 3.5e-83 1.1e-79 77 511 .. 101 548 .. 64 549 .. 0.80 Alignments for each domain: == domain 1 score: 269.1 bits; conditional E-value: 3.5e-83 CHGN 77 almyrlhkyfl..eleleklrkeieklqreiknmsellpekeeke................................swplgippslnrfkpksrs 138 +l+yrl + +l+++k ++e+ +l+ + +++ +++++++ + + + ++++f +++ + FUN_000401-T1 101 ELIYRLTAELEkeKLNVKKFKQEVGNLKVQNAELLAEMESHS--LgehsgrgeqirsddtrdnspastkeeldvqvsGIRISERVPFQSFAKTHVF 194 444444443321123334444444444333333222222222..1335666666666666666666666666655556666667777777788888 PP CHGN 139 evleWdyltekelysaedsqprreldgalkedledvieeaveeinekskqrgrvlefkellnGYrrvdplrGmdyildLlleyk.kekgkkmtvpv 233 ev + +l ke+ + ++r+l++ k+ l ++ + a++ in++ + r ++ ++++ G +r+d Gmdy l + + k FUN_000401-T1 195 EVSQ--TLRPKEYIFHGQDTNMRRLKSGRKHFL-EAQNVAINFINSNTSYR---VSRDNVVDGVYRFDINVGMDYELYFKDPSSsK-------YLA 277 8875..666655444444567889998888888.77899******999999...*********************88766555522.......344 PP CHGN 234 rrrvylqrplskveilkpvpyvtestrvniilPlsgrvetferFlenyekvclekeenvlllvvlydskkseeddfkkikelieelkkkykkakia 329 r ++l+ p++ v p ++++ ++ +n+ilPlsgr e+f++F++n+ +v ++k+++v l+vvly + +df+ +k+++++l++ y +k + FUN_000401-T1 278 VRLIRLLGPMQPVAA--PTERRKPRELINLILPLSGRIERFQQFIDNFVEVGIKKDNHVFLTVVLYGA-----KDFNYVKSTLKDLEASYGFKKYQ 366 445555555554443..5677888899****************************9999*********.....9********************** PP CHGN 330 visvkpsgefsraaaldlaakkl...ssdsLlfladvdlvftseflnrvRmNtiqgkqvyfPivFseYdpkivyadkkeeekeedafdvnkeaGhf 422 +i ++fsr++al+ ++ +++ Llf++dvd++f+++fl r+Rm + +k+vy+P+vFs Y+pk vy d + + ++++ +++ +G++ FUN_000401-T1 367 LIMRD--KPFSRGRALHDGVMYWsgkPRNILLFFCDVDITFRPDFLRRCRMYAEPQKKVYYPMVFSLYNPKNVYEDGTIP-PPSQQLIIERTHGFW 459 *9999..9***********998888799**********************************************655554.599************ PP CHGN 423 rrygfgivcfYksDyvavgGfrtsiegwgledvdlyekfvkysglhvfRavepgLvhiyhpreCdpslseeqykmClgskaeglasrkq 511 r ygfg++c Y+sDy++vgGf+++iegwg ed+ lyek++++s+++++Ra++++L h +h+++Cdpsls+eqy++Clgska + + +q FUN_000401-T1 460 RAYGFGMTCQYRSDYLRVGGFDLNIEGWGSEDLGLYEKLLQQSDIRIIRAPDRDLFHYFHEKKCDPSLSNEQYRSCLGSKAIAEGTHTQ 548 *********************************************************************************99888877 PP >> Glyco_transf_7C N-terminal domain of galactosyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.3 2.2e-10 7e-07 18 77 .. 460 519 .. 453 522 .. 0.83 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 2.2e-10 Glyco_transf_7C 18 elfG.GvlalskedfkkinGfsnkfwgWGgEDddlyaRlles.gleverpkkeigrytmlkh 77 + G G + +++d+ +++Gf+ + gWG ED ly++ll++ +++ r + ++++++ h FUN_000401-T1 460 RAYGfGMTCQYRSDYLRVGGFDLNIEGWGSEDLGLYEKLLQQsDIRIIRAPD--RDLFHYFH 519 5558799*******************************98875899999888..55555544 PP >> Glyco_tranf_2_2 Glycosyltransferase like family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 1.4e-07 0.00046 29 202 .. 332 501 .. 306 565 .. 0.77 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1.4e-07 Glyco_tranf_2_2 29 eielivvedgSsektleevssiidlnlqv....ylkdeddkayslaaarNrGaskaese....lvlFlDaDcfissDklekilklitikklren 114 + ++ v + ++++ + s+++dl+ y + dk +s ++a G+ + + l++F+D+D + +D l + ++ FUN_000401-T1 332 NHVFLTVVLYGAKDFNYVKSTLKDLEASYgfkkYQLIMRDKPFSRGRALHDGVMYWSGKprniLLFFCDVDITFRPDFLRRC-------RMYAE 418 44566777788888888888888887665211244458899***********99887754445899***********88764.......58999 PP Glyco_tranf_2_2 115 idaavvlpvvdlnkeasevlkdvedltassrvledllvakstlvkffapss.ssilinrrallevGGyDEsliGhgaEDfdlllRlaka 202 ++ v +p+v + ++v+ d t+ + +l++ + f ++ r +l+vGG+D ++ G g+ED l+ +l+++ FUN_000401-T1 419 PQKKVYYPMVFSLYNPKNVYE---DGTIPPPSQ-QLII--ERTHGFWRAYGfGMTCQYRSDYLRVGGFDLNIEGWGSEDLGLYEKLLQQ 501 9*******9999988998865...556665555.4555..44456999999778888899************************99875 PP >> Glycos_transf_2 Glycosyl transferase family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 4.7e-06 0.015 50 123 .. 358 436 .. 347 476 .. 0.77 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 4.7e-06 Glycos_transf_2 50 k..kdprvrvirreenrGlaaArnaglraatgd....yiaflDaDdevspdwleklvekleedgadvvvgsrvaisgetg 123 + ++ ++i r++ + ++A++ g+ +++g+ ++f+D D ++ pd+l+++ ++e ++ v+++ +++ + + FUN_000401-T1 358 AsyGFKKYQLIMRDKPFSRGRALHDGVMYWSGKprniLLFFCDVDITFRPDFLRRCRMYAEP-QKKVYYPMVFSLYNPKN 436 44567788999********************************************9999998.55566665555444444 PP >> PHM7_cyt Cytosolic domain of 10TM putative phosphate transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.3 4.9e-05 0.15 31 74 .. 79 122 .. 59 231 .. 0.83 2 ? -3.8 0.0 5.6 1.8e+04 33 48 .. 545 560 .. 527 565 .. 0.60 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4.9e-05 PHM7_cyt 31 vvesvqivrdvkkldklveerekavrkleaalakylkngkklpk 74 + +++q+v++vk+l++ +++re+++ +l+a l+k + n kk ++ FUN_000401-T1 79 ERSNAQLVKEVKRLQSRINKREELIYRLTAELEKEKLNVKKFKQ 122 55789*****************************9999988733 PP == domain 2 score: -3.8 bits; conditional E-value: 5.6 PHM7_cyt 33 esvqivrdvkkldklv 48 +++qi+ +++kl++ + FUN_000401-T1 545 THTQIAMQLSKLREKY 560 4556666666665544 PP >> GeBP-like_DBD Glabrous-enhancer-binding protein-like family, DBD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 1.2 0.049 1.6e+02 40 70 .. 73 103 .. 49 123 .. 0.78 2 ? 8.5 0.0 0.0014 4.6 19 69 .. 516 566 .. 504 570 .] 0.84 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.049 GeBP-like_DBD 40 kkslsfdvskeqlveKirrLkkkyenkakka 70 +k+++ + s+ qlv+ ++rL+ + ++ + + FUN_000401-T1 73 RKEIDMERSNAQLVKEVKRLQSRINKREELI 103 789999***************9988876555 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0014 GeBP-like_DBD 19 dfksktgkspkddldafyeavkkslsfdvskeqlveKirrLkkkyenkakk 69 + +++ +p+ + +++ + ++ ++ +++q++ + +L++kye+ +++ FUN_000401-T1 516 HYFHEKKCDPSLSNEQYRSCLGSKAIAEGTHTQIAMQLSKLREKYESDSQQ 566 566677777888888888889999999*******************87765 PP >> DUF7491 Coiled-coil region of unknown function (DUF7491) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 6.0 0.00025 0.79 4 66 .. 77 139 .. 66 158 .. 0.92 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00025 DUF7491 4 elqgeNrelrqqisdlsststkyeellrrkeselaiLradvkrheeekksLekekeslssrhd 66 +++ N +l ++++ l+s +k eel+ r el+ + +vk++++e +L+ ++++l ++ + FUN_000401-T1 77 DMERSNAQLVKEVKRLQSRINKREELIYRLTAELEKEKLNVKKFKQEVGNLKVQNAELLAEME 139 67788**************************************************99988766 PP >> CC4_CEP85 Centrosomal protein of 85 kDa-like, CC4 coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 8.6 0.00098 3.1 15 78 .. 73 135 .. 61 140 .. 0.87 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00098 CC4_CEP85 15 kkviekqqkkmeqlssqiqsLeeqvaqEegtsqaLreEalekenalqqLreavkELsvqnQdLi 78 +k i+ ++ ql +++ L++++ + e+ + L +E+ + ++++ ++ v +L vqn +L+ FUN_000401-T1 73 RKEIDM-ERSNAQLVKEVKRLQSRINKREELIYRLTAELEKEKLNVKKFKQEVGNLKVQNAELL 135 566665.456679999*********************************************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (570 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1350 (0.0528479); expected 510.9 (0.02) Passed bias filter: 748 (0.0292817); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.41u 0.34s 00:00:00.75 Elapsed: 00:00:00.48 # Mc/sec: 4799.09 // Query: FUN_000402-T1 [L=151] Description: FUN_000402 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-44 150.8 6.0 3.9e-44 150.5 6.0 1.0 1 Tropomodulin Tropomodulin ------ inclusion threshold ------ 0.15 12.8 1.0 0.27 12.0 0.5 1.6 1 DUF2267 Uncharacterized conserved protein (DUF2267) Domain annotation for each model (and alignments): >> Tropomodulin Tropomodulin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 150.5 6.0 3e-48 3.9e-44 3 132 .. 11 135 .. 9 140 .. 0.97 Alignments for each domain: == domain 1 score: 150.5 bits; conditional E-value: 3e-48 Tropomodulin 3 kelekykdidedellkkLseeeleqLekeleelDpdnallPaglRqkdqtkkeptgpfdRekLlkylekkAleekdredlvPftgekrGkvfvpke 98 +l+++kdided l++ Ls+ee+ +L+ +Dp+nallP + Rq +qt+k++tgpfdR++Ll++le++A++ek+r+d+vP+++e+rGkv+ pke FUN_000402-T1 11 VDLDEFKDIDEDVLVETLSPEEIADLNA---AIDPENALLPVNERQANQTNKASTGPFDRQHLLNHLEEQAKNEKERDDYVPYKKETRGKVWRPKE 103 699*************************...99*************************************************************** PP Tropomodulin 99 kkkeeekeeevtlddeleeaLesAteeelvdlAa 132 k++++e+e +l d+l+e+L++Ateee+++lA+ FUN_000402-T1 104 KSAKKEPEP--MLPDDLSEVLDNATEEEMLELAG 135 *99999999..9********************96 PP >> DUF2267 Uncharacterized conserved protein (DUF2267) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.5 2.1e-05 0.27 30 87 .. 23 84 .. 22 100 .. 0.81 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.1e-05 DUF2267 30 tlrerltveeaadLaaqLPeelrgllkegwdpse...pgk.rfdleeFlervaerlgvdpet 87 +l e l++ee adL a +e + l +++ + ++ + + +fd++ +l++ +e++++++e+ FUN_000402-T1 23 VLVETLSPEEIADLNAAIDPENALLPVNERQANQtnkASTgPFDRQHLLNHLEEQAKNEKER 84 7899**************999886665555554578977779**************777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (151 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1154 (0.0451752); expected 510.9 (0.02) Passed bias filter: 683 (0.0267371); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.43 # Mc/sec: 1400.93 // Query: FUN_000403-T1 [L=1692] Description: FUN_000403 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-40 136.2 6.3 3.9e-13 50.1 1.6 3.5 3 PDZ PDZ domain 4.4e-34 117.1 0.0 9.9e-34 116.0 0.0 1.6 1 ZU5 ZU5 domain 3.6e-19 68.7 4.5 7.1e-06 26.1 0.0 3.7 3 PDZ_6 PDZ domain 1.6e-18 67.2 2.8 1.6e-08 35.2 0.0 3.6 3 PDZ_2 PDZ domain 4.6e-14 53.0 0.0 8.2e-13 48.9 0.0 2.4 2 Guanylate_kin Guanylate kinase 1.8e-10 41.2 0.0 3.2e-10 40.3 0.0 1.5 1 CARD Caspase recruitment domain 1.9e-07 31.1 0.0 6.1e-07 29.5 0.0 2.0 1 SH3_2 Variant SH3 domain 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 UPA UPA domain 0.0017 18.0 0.5 0.013 15.2 0.2 2.3 3 DUF6288 Family of unknown function (DUF6288) 0.006 16.6 0.0 0.025 14.7 0.0 2.2 1 SH3_1 SH3 domain ------ inclusion threshold ------ 0.031 14.8 0.3 19 5.8 0.1 3.8 4 DUF4265 Domain of unknown function (DUF4265) Domain annotation for each model (and alignments): >> PDZ PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.1 1.6 1.7e-16 3.9e-13 2 80 .. 219 302 .. 218 303 .. 0.94 2 ! 40.4 0.0 1.8e-13 4.2e-10 2 80 .. 323 395 .. 322 396 .. 0.91 3 ! 46.4 0.0 2.4e-15 5.5e-12 6 79 .. 546 615 .. 541 617 .. 0.93 Alignments for each domain: == domain 1 score: 50.1 bits; conditional E-value: 1.7e-16 PDZ 2 vsleke.grgglGfslkggsdks.....dkgifvsevlpggaaeaggLkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 + lek ++g+G+ ++gg+d++ d++i+vs+++pg++ + Lk++D+I++vN+++ve++ h avqalk+s+++ +L i FUN_000403-T1 219 IVLEKAnANQGFGIAVSGGRDNPhfksgDTSIVVSDIVPGSPSDGL-LKVNDIIVQVNDVNVESVVHGVAVQALKDSGNSARLAI 302 67888889**********************************9888.*******************************9888876 PP == domain 2 score: 40.4 bits; conditional E-value: 1.8e-13 PDZ 2 vsleke.grgglGfslkggsdksdkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 v+l ++ + +g Gfsl g + f++e+ ++g+ +++g L +GD+Il+vN++++e++s+ ea++ +++s+ + L++ FUN_000403-T1 323 VTLIRDqQYKGYGFSLGG-------SMFIKEIDKNGMVARQGeLTPGDIILRVNDRKTEEMSLREAIDTVRRSN-RLDLLV 395 666677688899999998.......9**********************************************97.888876 PP == domain 3 score: 46.4 bits; conditional E-value: 2.4e-15 PDZ 6 kegrgglGfslkggsdksdkgifvsevlpggaaeaggLkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLt 79 + + g+lG++++gg++ +gifv+ v +g++a gL+ GD++l N+ d+++++ eeav+ l + +++v L+ FUN_000403-T1 546 R-KSGSLGIQVSGGNK---TGIFVAAVKEGSPAYNEGLRTGDQVLMANDIDFKDITREEAVLILLSLGDEVNLL 615 4.899********999...5**************************************************9997 PP >> ZU5 ZU5 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 116.0 0.0 4.3e-37 9.9e-34 2 97 .] 1389 1486 .. 1388 1486 .. 0.96 Alignments for each domain: == domain 1 score: 116.0 bits; conditional E-value: 4.3e-37 ZU5 2 savvdsrGgrlvlpntgvsllvPegaipegtrieiylavlkkesslp..kleegetllspvvecGPsglkfskpvilevpHcaslkseeweisl 93 ++ ++s+Gg+l++p++gvs+++Pegaip+g+++eiy++v+k+++ +p +++ getllsp+v+cGP+g++f+kpv+l++pHcas++++ w+++l FUN_000403-T1 1389 RGKFTSQGGVLSSPESGVSIVIPEGAIPKGVEQEIYFKVCKDNNFMPplDSDRGETLLSPLVMCGPHGTEFLKPVELRLPHCASMTPDGWSFAL 1482 5779****************************************999788899***************************************** PP ZU5 94 krsd 97 k+sd FUN_000403-T1 1483 KSSD 1486 *986 PP >> PDZ_6 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 1.2 2.8e-08 6.5e-05 1 54 [] 251 304 .. 251 304 .. 0.81 2 ! 18.5 0.0 7.5e-07 0.0017 2 41 .. 344 386 .. 343 396 .. 0.78 3 ! 26.1 0.0 3.1e-09 7.1e-06 1 51 [. 564 615 .. 564 617 .. 0.77 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 2.8e-08 PDZ_6 1 vvtavvpgsPAerAG.lrvGDiIlsvNGepvrsle..dvarllqgaggesvrllvrR 54 vv+++vpgsP + G l+v+DiI++vN+++v s+ ++++l+ + g s rl ++R FUN_000403-T1 251 VVSDIVPGSPSD--GlLKVNDIIVQVNDVNVESVVhgVAVQALK-DSGNSARLAIKR 304 799*********..99***************8876466777777.666666666665 PP == domain 2 score: 18.5 bits; conditional E-value: 7.5e-07 PDZ_6 2 vtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllq 41 +++++++++ +r G l +GDiIl vN++++ +sl ++++ ++ FUN_000403-T1 344 IKEIDKNGMVARQGeLTPGDIILRVNDRKTeeMSLREAIDTVR 386 667777777777777***************8887778777665 PP == domain 3 score: 26.1 bits; conditional E-value: 3.1e-09 PDZ_6 1 vvtavvpgsPAerAGlrvGDiIlsvNGepvrsle..dvarllqgaggesvrll 51 +v+av++gsPA++ Glr GD +l+ N+++ ++++ +++ +l + g++v+ll FUN_000403-T1 564 FVAAVKEGSPAYNEGLRTGDQVLMANDIDFKDITreEAVLILL-SLGDEVNLL 615 699***************************6655325555544.666666666 PP >> PDZ_2 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.3 5.7e-07 0.0013 7 71 .. 243 306 .. 229 313 .. 0.84 2 ! 10.5 0.0 0.00034 0.79 14 70 .. 342 398 .. 322 401 .. 0.77 3 ! 35.2 0.0 6.7e-12 1.6e-08 1 69 [. 549 620 .. 549 627 .. 0.91 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 5.7e-07 PDZ_2 7 fedledgvvVvnVksssPaakaglkagDvIlsidgkkvksltdleeallkkkpgdtvklqvlRdg 71 f++ + ++vV ++ ++sP++ lk++D+I+++++ v+s + + + k+ g ++l ++R + FUN_000403-T1 243 FKSGDTSIVVSDIVPGSPSDGL-LKVNDIIVQVNDVNVESVVHGVAVQALKDSGNSARLAIKRRK 306 34444599**********7776.********************9999999999999999999976 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00034 PDZ_2 14 vvVvnVksssPaakag.lkagDvIlsidgkkvksltdleeallkkkpgdtvklqvlRd 70 + ++++++ a++g l +gD+Il+++++k + +l+ea+ + ++ ++ l v++d FUN_000403-T1 342 MFIKEIDKNGMVARQGeLTPGDIILRVNDRKTEE-MSLREAIDTVRRSNRLDLLVIKD 398 56788999999999999*************9754.45666666666666666666655 PP == domain 3 score: 35.2 bits; conditional E-value: 6.7e-12 PDZ_2 1 gdlGisfedled.gvvVvnVksssPaakaglkagDvIlsidgkkvksltdleeallkkkpgdtvkl..qvlR 69 g lGi+++ ++ g+ V+ Vk++sPa ++gl++gD++l++++ +k+ t e +l ++ gd+v+l q++R FUN_000403-T1 549 GSLGIQVSGGNKtGIFVAAVKEGSPAYNEGLRTGDQVLMANDIDFKDITREEAVLILLSLGDEVNLlcQYKR 620 689****987766****************************************************9445555 PP >> Guanylate_kin Guanylate kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.19 4.4e+02 3 33 .. 770 797 .. 769 800 .. 0.91 2 ! 48.9 0.0 3.5e-16 8.2e-13 84 179 .. 821 920 .. 813 923 .. 0.80 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.19 Guanylate_kin 3 rplvllgpsgaGksslkkaLlselpekfgvs 33 rp+vllgp + +++Ll+ p+ f+++ FUN_000403-T1 770 RPVVLLGPI---ADITRDKLLQDMPDVFAIP 797 89*******...9999**********99876 PP == domain 2 score: 48.9 bits; conditional E-value: 3.5e-16 Guanylate_kin 84 eaieevlekgkiviLDvdiqavkqlrkaelspiivFikppslkelqrrlks..rgeeqeeklak...rlaaaekeleeyefdvvivnddleealkk 174 + i+ v ++gk+++LD+ ++ v++l+ a+l+pi++F++pps++ ++++ + +g+++ ++++k ++ ++e+ ++++ f+vvi +l++ +++ FUN_000403-T1 821 NVIRSVIDSGKHCLLDITPEEVERLNYAQLYPIVIFLRPPSKQMVKEMRSQhgIGDQSTKMIKKlhdNSLKLEEFYSNM-FTVVIPAGSLDNWYAN 915 679******************************************9886541156667666655111444455555555.**************** PP Guanylate_kin 175 lkell 179 +k+ + FUN_000403-T1 916 VKDEI 920 *9876 PP >> CARD Caspase recruitment domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.3 0.0 1.4e-13 3.2e-10 2 83 .. 9 89 .. 8 91 .. 0.96 Alignments for each domain: == domain 1 score: 40.3 bits; conditional E-value: 1.4e-13 CARD 2 ellkknrvaLverlktlsglldaLleknVLteeeeekikakttrqdkareLldlvlkkgekaaqiFlealkegdpdLasdle 83 ++l +nr L++++ +++ + L+ +VL+++e+++i+ +t+q++++ Lldl++ kg+ ++ F+ al++++p+La +l+ FUN_000403-T1 9 SALLENRDILLRDVR-ANDVCPLLYVSGVLSQKEIDDINIGRTNQERTESLLDLLHYKGPGGFHEFCVALEDTHPHLAAKLR 89 67899**********.**************************************************************9986 PP >> SH3_2 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 2.6e-10 6.1e-07 1 55 [] 635 697 .. 635 697 .. 0.90 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 2.6e-10 SH3_2 1 ygrvifdyvgtdkngLslkkGdvvkVlggkddd...gwweg.et..gGrk...GlvPstaveei 55 y++v+fdy+ ++n+Ls+++ dv+++ ++ d g+w++ ++ G++ G++P+++++e+ FUN_000403-T1 635 YIKVHFDYDKMKENELSFQREDVFHIW-DTMHDgviGSWQAqMVtkTGQEttiGIIPNKSRAEQ 697 89*************************.888888899****5447878889*********9986 PP >> UPA UPA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 1.3e-07 0.0003 1 119 [. 1543 1659 .. 1543 1679 .. 0.79 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1.3e-07 UPA 1 avkrLklavfaplactsleyslrvyclddtqdalkevlqlekklGGklleePktllfkdsthnLrlsiedvpkslWkskllakyqeipfshiWs 94 a+kr+ avfap ++ l +ddt++a+k+v + e +lG + + +l ++ + ++r+ ++d+ + W ++ k + i fs W FUN_000403-T1 1543 ATKRMLAAVFAPPPRVNDDWALNLVLMDDTEAAFKDVCNSEAELGRFPFSAFRPVLVHGDASDIRVQLRDLNNN-WIARSSCK-KYIEFSDSWE 1634 789999******999999*****************************************************999.88776554.4588999999 PP UPA 95 gsqkaLhCtftlerlslatselsck 119 + ++a f + + + ++ +c FUN_000403-T1 1635 AYRHAPCVEFLIRDRNFSPTSSVCV 1659 8887766666665444444443443 PP >> DUF6288 Family of unknown function (DUF6288) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.2 5.4e-06 0.013 2 33 .. 249 280 .. 248 309 .. 0.75 2 ? -2.9 0.0 1.7 3.9e+03 15 34 .. 355 375 .. 342 384 .. 0.73 3 ? -0.3 0.0 0.27 6.3e+02 3 35 .. 563 596 .. 561 628 .. 0.75 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 5.4e-06 DUF6288 2 qikvtkveegSPAdGklkvgdvilgvngktlk 33 +i v + gSP+dG lkv+d+i+ vn ++++ FUN_000403-T1 249 SIVVSDIVPGSPSDGLLKVNDIIVQVNDVNVE 280 5889999********************99665 PP == domain 2 score: -2.9 bits; conditional E-value: 1.7 DUF6288 15 d.Gklkvgdvilgvngktlkk 34 G l+ gd+il vn ++ ++ FUN_000403-T1 355 RqGELTPGDIILRVNDRKTEE 375 359************997664 PP == domain 3 score: -0.3 bits; conditional E-value: 0.27 DUF6288 3 ikvtkveegSPAd.Gklkvgdvilgvngktlkkf 35 i v +v+egSPA l+ gd +l +n +k++ FUN_000403-T1 563 IFVAAVKEGSPAYnEGLRTGDQVLMANDIDFKDI 596 5688899999997655777777777777755544 PP >> SH3_1 SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 1.1e-05 0.025 2 29 .. 638 665 .. 637 690 .. 0.83 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.1e-05 SH3_1 2 AlYDYeaeesdELsfkkGdviivlekse 29 + +DY++++++ELsf++ dv+++ + + FUN_000403-T1 638 VHFDYDKMKENELSFQREDVFHIWDTMH 665 569*******************987655 PP >> DUF4265 Domain of unknown function (DUF4265) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 3.8 8.8e+03 18 33 .. 572 587 .. 570 597 .. 0.81 2 ? 0.0 0.0 0.49 1.1e+03 25 59 .. 606 641 .. 603 658 .. 0.82 3 ? 5.8 0.1 0.0082 19 37 75 .. 669 708 .. 651 719 .. 0.81 4 ? 3.4 0.0 0.045 1e+02 66 110 .. 879 926 .. 864 930 .. 0.76 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 3.8 DUF4265 18 iPffakgvAlgDvvrv 33 +P++ +g+ +gD v + FUN_000403-T1 572 SPAYNEGLRTGDQVLM 587 8************988 PP == domain 2 score: 0.0 bits; conditional E-value: 0.49 DUF4265 25 vAlgDvvrvdedderlavervvkesGns.tirvlld 59 ++lgD v++ + +r ++rv ke G+s i+v +d FUN_000403-T1 606 LSLGDEVNLLCQYKRADFDRVSKETGDSfYIKVHFD 641 689******99999999****999987625777666 PP == domain 3 score: 5.8 bits; conditional E-value: 0.0082 DUF4265 37 derlavervvkesGnstirvlldesaelk.qevrerLeel 75 +++ ++v+k++ ++ti +++++s +++ ++v+ ++eel FUN_000403-T1 669 IGSWQAQMVTKTGQETTIGIIPNKSRAEQlAQVQHKVEEL 708 468999*********************9999999999987 PP == domain 4 score: 3.4 bits; conditional E-value: 0.045 DUF4265 66 qevrerLeelgceveassekllAvdvpp...dadlkaikklLeelede 110 +++++L++ ++++e +++++++v +p+ d+ ++++k+ ++ +++e FUN_000403-T1 879 TKMIKKLHDNSLKLEEFYSNMFTVVIPAgslDNWYANVKDEIKIQQEE 926 678999*********************833344577777776666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1692 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 986 (0.0385986); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.53u 0.41s 00:00:00.94 Elapsed: 00:00:00.43 # Mc/sec: 15904.25 // Query: FUN_000405-T1 [L=95] Description: FUN_000405 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (95 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 223 (0.00872969); expected 510.9 (0.02) Passed bias filter: 217 (0.00849481); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.34s 00:00:00.61 Elapsed: 00:00:00.61 # Mc/sec: 634.77 // Query: FUN_000406-T1 [L=107] Description: FUN_000406 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 582 (0.0227833); expected 510.9 (0.02) Passed bias filter: 371 (0.0145234); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.22u 0.40s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1105.99 // Query: FUN_000407-T1 [L=633] Description: FUN_000407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-61 204.4 1.2 6.6e-15 55.4 0.0 5.0 5 I-set Immunoglobulin I-set domain 1.5e-60 202.1 6.9 6.7e-16 59.0 0.1 5.5 5 Ig_3 Immunoglobulin domain 1.2e-42 144.5 5.1 1.9e-12 47.7 0.1 4.4 4 Ig_2 Immunoglobulin domain 4.7e-32 110.6 12.4 1.6e-07 32.0 0.1 5.2 5 ig Immunoglobulin domain 1.3e-29 102.7 1.7 2.1e-13 50.7 0.4 2.8 2 fn3 Fibronectin type III domain 6.9e-19 68.2 0.2 0.00058 20.3 0.0 4.9 4 C2-set_2 CD80-like C2-set immunoglobulin domain 5e-17 62.6 12.9 0.0071 17.0 0.0 8.2 7 V-set Immunoglobulin V-set domain 1e-10 41.9 0.3 0.17 12.3 0.0 4.4 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 3.5e-10 40.6 0.0 6e-06 27.0 0.0 3.9 3 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 6.4e-09 36.5 0.3 0.0009 20.0 0.0 2.7 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 1.6e-08 35.4 0.5 0.12 13.4 0.0 5.6 5 Ig_4 T-cell surface glycoprotein CD3 delta ch 4.2e-08 33.8 0.7 0.27 11.7 0.0 3.9 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor 6.7e-08 33.3 3.6 0.61 11.0 0.0 5.2 4 C1-set Immunoglobulin C1-set domain 9.4e-07 29.8 1.4 0.072 14.2 0.0 3.8 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal doma 1.1e-05 26.1 0.2 0.74 10.6 0.0 3.8 3 Ig_Rha78A_N Rha78A-like, N-terminal immunoglobulin d 8.1e-05 23.5 0.0 22 6.1 0.0 4.4 4 Shr-like_HID Heme-binding protein Shr-like, Hb-intera 0.00039 21.1 0.1 2.6 8.7 0.0 4.2 4 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.0004 20.8 0.1 0.72 10.3 0.0 4.2 4 Sp38 Zona-pellucida-binding protein (Sp38) N- 0.00047 20.2 0.2 0.00089 19.3 0.2 1.4 1 DUF4998 Domain of unknown function 0.00049 20.4 0.1 0.69 10.2 0.0 3.8 4 V-set_CD47 CD47 immunoglobulin-like domain 0.00063 20.5 0.0 0.081 13.7 0.1 2.6 2 Interfer-bind Interferon-alpha/beta receptor, fibronec 0.0016 19.0 0.0 0.27 11.8 0.0 2.6 2 NDNF Neuron-derived neurotrophic factor, firs 0.0043 17.6 0.3 0.17 12.5 0.1 2.7 2 InlK_D3 Internalin K domain (D3/D4) ------ inclusion threshold ------ 0.013 16.7 1.4 9.9 7.5 0.0 3.5 3 Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain 0.037 14.4 0.0 1.7 9.0 0.0 2.8 2 Ig_6 Immunoglobulin domain 0.043 14.4 0.3 0.22 12.1 0.2 2.2 2 Ig_J Tip attachment protein J, Ig-like domain 0.052 14.0 0.0 0.13 12.8 0.0 1.6 1 DUF6788 Domain of unknown function (DUF6788) 0.068 13.6 0.1 23 5.4 0.0 3.9 3 fn3_4 Fibronectin-III type domain 0.078 13.9 0.5 45 5.0 0.1 3.5 3 Cadherin Cadherin domain 0.17 12.3 0.2 24 5.4 0.0 2.6 2 Y_Y_Y Y_Y_Y domain Domain annotation for each model (and alignments): >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.4 0.0 1.2e-15 1.1e-12 1 88 [. 28 118 .. 28 120 .. 0.86 2 ! 41.4 0.1 1.9e-13 1.6e-10 3 85 .. 127 209 .. 125 213 .. 0.84 3 ! 55.4 0.0 7.7e-18 6.6e-15 2 90 .] 229 315 .. 228 315 .. 0.94 4 ! 53.8 0.0 2.6e-17 2.2e-14 1 90 [] 319 404 .. 319 404 .. 0.92 5 ? -1.6 0.0 4.8 4.1e+03 10 40 .. 536 566 .. 527 586 .. 0.71 Alignments for each domain: == domain 1 score: 48.4 bits; conditional E-value: 1.2e-15 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee..gtatLtIsnvkkeDeGkYtckatns.ageaeasaeL 88 p+f ++++d+ v++G+ a+l+c+v G+p p+++W+++g++++ ++r +k ++ ++++ ++ k DeG Y+c+ + s ++ + +a++ FUN_000407-T1 28 PHFIEEPSDTYVRKGKPATLKCQVGGNPLPSITWKRNGKQVTLDSRRTIKPDGslYFTEIFHNRTHKPDEGVYQCEGSQSyYKIISRTARV 118 89***************************************************555556666889999*******9888744444555555 PP == domain 2 score: 41.4 bits; conditional E-value: 1.9e-13 I-set 3 ftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselke..skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 ++ +k +v+ G++a+l c+v+ + p+ +v W k+gs+++ ++r+ + ++ L I+n++ e++GkY+c atn++ +++++ FUN_000407-T1 127 VDVVPKTSSVTFGDTARLFCNVKHSnPKAKVGWRKQGSNVSIttGDRFTLIPNG---ALQINNLRFEEQGKYECFATNEIARKTHT 209 67789999**************9655**********776655338888888888...9*********************8777665 PP == domain 3 score: 55.4 bits; conditional E-value: 7.7e-18 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +f++++kd+++++++++ lec +sG p+p+++Wlkdg e+++ ++ +++ ++ L+I++v + +G+Ytc+a+ + + a+a+L V FUN_000407-T1 229 SFQTRPKDTVATTESTVVLECVASGYPKPSITWLKDGFEISPgQNGYSILGQG---NLMIKSVAVSHAGTYTCRASQTTRSFDATAKLDV 315 799***************************************66678888888...***************************9999987 PP == domain 4 score: 53.8 bits; conditional E-value: 2.6e-17 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p ft+k++dv + + +++++ec++ G p+p++sW+ +g+el++s+ +v + L+++++ +D+G Y+c a+ +g+++as +L V FUN_000407-T1 319 PVFTKKPSDVHAYKKSRVQFECQAAGIPKPNISWSLNGRELSTSSYTRVG----DGVLEVRDLVFSDKGVYQCFAKGHSGKVQASGQLFV 404 78****************************************87655554....457***************************999876 PP == domain 5 score: -1.6 bits; conditional E-value: 4.8 I-set 10 vevkeGesaeleckvsGepepevsWlkdgse 40 ++ G+ +l +++ e ++v+W ++ FUN_000407-T1 536 SSAVPGKPRDLVAEAVTESSIRVTWEVPDTG 566 5566778888888899999999***988764 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.5 0.1 3.1e-15 2.7e-12 2 76 .. 28 104 .. 28 105 .. 0.78 2 ! 41.5 0.0 2.3e-13 2e-10 6 78 .] 129 201 .. 126 201 .. 0.84 3 ! 59.0 0.1 7.8e-19 6.7e-16 5 77 .. 231 301 .. 225 301 .. 0.90 4 ! 51.8 0.0 1.4e-16 1.2e-13 2 77 .. 319 390 .. 318 390 .. 0.92 5 ? 1.1 0.1 0.96 8.1e+02 4 51 .. 529 577 .. 528 609 .. 0.67 Alignments for each domain: == domain 1 score: 47.5 bits; conditional E-value: 3.1e-15 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskrsssssnstLtisnvtredsGtYtCvA 76 P + +ps+t v++g+++tL+C++ gnp p+itW++ngk+ l+s +t k s + +++ +++++ d+G Y+C+ FUN_000407-T1 28 PHFIEEPSDTYVRKGKPATLKCQVGGNPLPSITWKRNGKQvtLDSRRTIKPDGSLYFTEIFHNRTHKPDEGVYQCEG 104 778889*********************************764333333322555555555555699*********85 PP == domain 2 score: 41.5 bits; conditional E-value: 2.3e-13 Ig_3 6 vspsstvveegesvtLtCea.egnppptitWykngke..lssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 v p++++v+ g++++L C++ ++np+ ++ W+k+g++ +++ + n+ L+i+n+++e +G+Y+C A+N FUN_000407-T1 129 VVPKTSSVTFGDTARLFCNVkHSNPKAKVGWRKQGSNvsITT-----GdrFTLIPNGALQINNLRFEEQGKYECFATN 201 45666779************7777777*********653333.....23379*************************9 PP == domain 3 score: 59.0 bits; conditional E-value: 7.8e-19 Ig_3 5 tvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 ++ p++tv++ ++v+L+C a+g+p+p+itW+k+g e+s+g+ +s ++++L i++v +++GtYtC+As FUN_000407-T1 231 QTRPKDTVATTESTVVLECVASGYPKPSITWLKDGFEISPGQNG--YSILGQGNLMIKSVAVSHAGTYTCRAS 301 47889999****************************98886666..79***********************97 PP == domain 4 score: 51.8 bits; conditional E-value: 1.4e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 Pv+t +ps++++ ++++v+++C+a+g p+p+i+W+ ng+els+ s+ ++ + ++L+++++ ++d G Y+C A+ FUN_000407-T1 319 PVFTKKPSDVHAYKKSRVQFECQAAGIPKPNISWSLNGRELST---SS-YTRVGDGVLEVRDLVFSDKGVYQCFAK 390 9**************************************6444...32.4689********************995 PP == domain 5 score: 1.1 bits; conditional E-value: 0.96 Ig_3 4 itvspsstvveegesvtLtCeaegnppptitWykngkelssgstskr...s 51 itv s+++++g++ L ea +++ ++tW +++ ++s++ FUN_000407-T1 529 ITVRTYSSSAVPGKPRDLVAEAVTESSIRVTWEVPDT--GPVSRYVIlykD 577 5655556667889999999999888888999999998..343333335442 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.6 0.1 4.9e-15 4.1e-12 5 79 .] 33 120 .. 29 120 .. 0.88 2 ! 25.2 0.1 2.4e-08 2.1e-05 7 74 .. 132 210 .. 126 218 .. 0.75 3 ! 47.7 0.1 2.2e-15 1.9e-12 3 67 .. 231 304 .. 229 315 .. 0.90 4 ! 24.2 0.0 4.8e-08 4.1e-05 6 71 .. 325 396 .. 318 404 .. 0.76 Alignments for each domain: == domain 1 score: 46.6 bits; conditional E-value: 4.9e-15 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn............fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++s+t v++g++ tL+C++ gnp +++tw ++gk + +s++ +f+++ + d G+Y+C+ +++ ++ s++ ++tv FUN_000407-T1 33 EPSDTYVRKGKPATLKCQVGGNPLPSITWKRNGKQVTlDSRRtikpdgslyfteIFHNRTHKPDEGVYQCEGSQSYYKIISRTARVTV 120 366699***************************99888555557777889777777799**************************998 PP == domain 2 score: 25.2 bits; conditional E-value: 2.4e-08 Ig_2 7 sptvvtegesvtLtCsas.gnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnp 74 ++ vt g++ +L C ++ +np+ak+ w+k+g+ +s ++ + + ++n e +G Y C a+n+ k+ + FUN_000407-T1 132 KTSSVTFGDTARLFCNVKhSNPKAKVGWRKQGSNVSiTTGDrftlipngaLQINNLRFEEQGKYECFATNEIARKTHTS 210 3477999**********999************9999844444544444434468899************9666554444 PP == domain 3 score: 47.7 bits; conditional E-value: 2.2e-15 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn.........fftsnvsaedsGtYtCtarntk 67 + ++ +tv t+ ++v L C asg p++++tw kdg ++s++qn + +++v ++++GtYtC+a++t FUN_000407-T1 231 QTRPKDTVATTESTVVLECVASGYPKPSITWLKDGFEISPGQNgysilgqgnLMIKSVAVSHAGTYTCRASQTT 304 56777799***********************************999999988889***************9864 PP == domain 4 score: 24.2 bits; conditional E-value: 4.8e-08 Ig_2 6 asptvvtegesvtLtCsasgnppakytwykdgkvls..ssqn......fftsnvsaedsGtYtCtarntkggkv 71 +s+ + +++ v++ C+a g p+++++w +g++ls s+ + ++ +d+G+Y+C a+ ++ gkv FUN_000407-T1 325 PSDVHAYKKSRVQFECQAAGIPKPNISWSLNGRELStsSY-TrvgdgvLEVRDLVFSDKGVYQCFAKGHS-GKV 396 4447889*****************************6333.24676644467899*********998544.554 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.0 0.1 1.9e-10 1.6e-07 3 71 .. 37 105 .. 35 108 .. 0.87 2 ! 28.1 0.2 3.2e-09 2.7e-06 2 74 .. 133 203 .. 132 209 .. 0.89 3 ! 25.9 0.1 1.5e-08 1.3e-05 5 73 .. 239 303 .. 235 310 .. 0.90 4 ! 29.7 0.0 9.9e-10 8.5e-07 5 79 .. 330 398 .. 326 399 .. 0.94 5 ? -1.9 0.0 7.3 6.2e+03 21 38 .. 553 570 .. 546 594 .. 0.62 Alignments for each domain: == domain 1 score: 32.0 bits; conditional E-value: 1.9e-10 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk.vkedngrttqssllisnvteedaGtYtCvvn 71 ++v++G+ atL C + g+p p++tW+++gk+ ++ ++ + + +g+ + +++ +++ + d+G Y C+++ FUN_000407-T1 37 TYVRKGKPATLKCQVG-GNPLPSITWKRNGKQVTLDSRrTIKPDGSLYFTEIFHNRTHKPDEGVYQCEGS 105 789*************.*********************64444455555589999999*********997 PP == domain 2 score: 28.1 bits; conditional E-value: 3.2e-09 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 t v G++a+L C++++++p + v W+k+g+ ++ + ++ + + l+i+n ++e G Y C ++n+ FUN_000407-T1 133 TSSVTFGDTARLFCNVKHSNPKAKVGWRKQGSNVSITTG--DRFTLIPNGALQINNLRFEEQGKYECFATNEI 203 568999************************998777766..778888888*******************9975 PP == domain 3 score: 25.9 bits; conditional E-value: 1.5e-08 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 + +++++L C as g p p++tW k+g ++ ++ ++ +q +l i +v ++aGtYtC+++ + FUN_000407-T1 239 ATTESTVVLECVAS-GYPKPSITWLKDGFEISPGQN---GYSILGQGNLMIKSVAVSHAGTYTCRASQT 303 56689*********.*************99999988...88888999******************9865 PP == domain 4 score: 29.7 bits; conditional E-value: 9.9e-10 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 +++ +++++ C a g p p+++Ws +g ++ +s++ +r+++ l +++ ++d G Y C + ++g++++ FUN_000407-T1 330 AYKKSRVQFECQAA-GIPKPNISWSLNGRELSTSSY-----TRVGDGVLEVRDLVFSDKGVYQCFAKGHSGKVQA 398 677899********.*********************.....**************************99999887 PP == domain 5 score: -1.9 bits; conditional E-value: 7.3 ig 21 spgpdvtWskegktkies 38 ++ + vtW++ ++ + + FUN_000407-T1 553 ESSIRVTWEVPDTGPVSR 570 667778888877766554 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.1 0.0 3.9e-16 3.3e-13 2 83 .. 444 531 .. 443 532 .. 0.87 2 ! 50.7 0.4 2.5e-16 2.1e-13 2 77 .. 542 618 .. 541 625 .. 0.88 Alignments for each domain: == domain 1 score: 50.1 bits; conditional E-value: 3.9e-16 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+n+ ++ ++t+++++W+pp ++g+i +Y y ++++ v+g++ ++++L+p+teY+++V a n++G g se+++v FUN_000407-T1 444 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVKAGGsnvdtvIVSGDTlV--KQFSDLEPDTEYQFNVFAKNKHGTGAISEEITV 531 7******99999***********99*************88886665555555332..568**************************9987 PP == domain 2 score: 50.7 bits; conditional E-value: 2.5e-16 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne...tvpgsr.etsvtltgLkpgteYevrVqavngaGegee 77 +P++l +++vt++s++v+W+ pd gp+++Y + y+++++ ++++++ +++ l++Lk +t+Y+++V+a ++G ++ FUN_000407-T1 542 KPRDLVAEAVTESSIRVTWEVPD-TGPVSRYVILYKDTSSnerELQDNTkKQTRVLRDLKTYTKYTITVYAEDKDG--MR 618 7*********************5.9************76677****9998777889***************98875..44 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 3.9e-06 0.0033 13 72 .. 41 97 .. 29 104 .. 0.75 2 ! 8.9 0.0 0.0026 2.2 13 45 .. 139 169 .. 127 194 .. 0.76 3 ! 20.3 0.0 6.9e-07 0.00058 8 41 .. 236 268 .. 230 307 .. 0.81 4 ! 14.7 0.0 4e-05 0.034 14 47 .. 333 363 .. 321 373 .. 0.76 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 3.9e-06 C2-set_2 13 eekevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredn 72 ++k +++C gg+P p+itW ++gk++ + ++++++p+ l+ + + ++ ++++ d FUN_000407-T1 41 KGKPATLKC-QVGGNPLPSITWKRNGKQV-TLDSRRTIKPDGSLYFT-EIFHNRTHKPDE 97 356788999.779***************9.77777777777777766.888888887776 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0026 C2-set_2 13 eekevvatCvsaggkPapritWlldgkeleaae 45 + + + C ++ ++P++++ W ++g ++ ++ FUN_000407-T1 139 G-DTARLFCNVKHSNPKAKVGWRKQGSNV-SIT 169 4.566778******************998.333 PP == domain 3 score: 20.3 bits; conditional E-value: 6.9e-07 C2-set_2 8 slleaeekevvatCvsaggkPapritWlldgkel 41 ++ ++e +vv++C +a+g+P+p+itWl+dg e+ FUN_000407-T1 236 DTVATTESTVVLEC-VASGYPKPSITWLKDGFEI 268 344455699*****.899************9776 PP == domain 4 score: 14.7 bits; conditional E-value: 4e-05 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaaets 47 + +v ++C a g P+p+i+W l+g+el +++s FUN_000407-T1 333 KSRVQFEC-QAAGIPKPNISWSLNGREL--STSS 363 56889999.8889***************..3333 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.4 0.0013 1.1 3 108 .. 34 120 .. 32 121 .. 0.59 2 ! 14.5 0.1 5.1e-05 0.043 6 99 .. 134 209 .. 129 219 .. 0.64 3 ? 3.4 0.0 0.14 1.2e+02 3 36 .. 234 264 .. 232 269 .. 0.88 4 ! 17.0 0.0 8.4e-06 0.0071 63 108 .. 276 315 .. 266 316 .. 0.83 5 ? -2.1 0.0 7.3 6.2e+03 2 36 .. 324 355 .. 323 364 .. 0.80 6 ! 12.3 0.0 0.00024 0.2 65 104 .. 362 400 .. 353 405 .. 0.73 7 ? 1.0 0.0 0.78 6.6e+02 25 62 .. 552 589 .. 535 609 .. 0.74 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0013 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgev 98 p+ + v G+ +tL+C++ + + s++W r ++ ++ ++ + k++g ++ +++ + + D+G+Y+C+ +++ FUN_000407-T1 34 PSDTYVRKGKPATLKCQVGGN---PLPSITWKRNGKQ------VTLD--SRRTIKPDGSLYFT--------EIFHNRTHKPDEGVYQCEGSQSYYK 110 555666677777777777766...7777777775543......2222..12233333333444........4777778888999999995555555 PP V-set 99 vfgkgtrLtV 108 +++ r+tV FUN_000407-T1 111 IISRTARVTV 120 5888888887 PP == domain 2 score: 14.5 bits; conditional E-value: 5.1e-05 V-set 6 vtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekk.kgrfslrkdpsrsdfsltiqnltlsDsGtYtCav...ipkge 97 +v G +++L C ++ s ++ +v W +q s+++++ ++rf+l ++ l+i+nl+ + +G Y+C + i++++ FUN_000407-T1 134 SSVTFGDTARLFCNVKHS--NPKAKVGWRKQG---------------SNVSITtGDRFTLIP-----NGALQINNLRFEEQGKYECFAtneIARKT 207 555555555555555544..555555555555...............44555559*******.....*******************9533333333 PP V-set 98 vv 99 + FUN_000407-T1 208 HT 209 33 PP == domain 3 score: 3.4 bits; conditional E-value: 0.14 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrq 36 p+ + + ++ +v L C+ s + + s++W ++ FUN_000407-T1 234 PKDTVATTESTVVLECVASGY---PKPSITWLKD 264 7778889999******99999...*******985 PP == domain 4 score: 17.0 bits; conditional E-value: 8.4e-06 V-set 63 slrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 s+ + + l i+++ +s++GtYtC+ ++ + +f ++ +L V FUN_000407-T1 276 SILG-----QGNLMIKSVAVSHAGTYTCR-ASQTTRSFDATAKLDV 315 4444.....899*****************.8999999999998877 PP == domain 5 score: -2.1 bits; conditional E-value: 7.3 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrq 36 +p+ v++ +v++ C+ + ++W+ FUN_000407-T1 324 KPSDVHAYKKSRVQFECQAAGI---PKPNISWSLN 355 5788888999999999988887...8888998865 PP == domain 6 score: 12.3 bits; conditional E-value: 0.00024 V-set 65 rkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 + ++ +d+ l++++l sD G+Y+C + + +++ +++ FUN_000407-T1 362 SSYTRVGDGVLEVRDLVFSDKGVYQCFA-KGHSGKVQASG 400 4467899*******************94.44444444444 PP == domain 7 score: 1.0 bits; conditional E-value: 0.78 V-set 25 seasqsvyWyrqppgkepteliayysnkseeekkkgrf 62 +e s +v+W ++g ++++i+y ++s+e ++ FUN_000407-T1 552 TESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDNT 589 4578899****999988888888888855554444443 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.0039 3.3 17 58 .. 45 84 .. 37 102 .. 0.74 2 ! 8.1 0.0 0.0042 3.6 15 82 .. 140 204 .. 133 209 .. 0.79 3 ! 7.6 0.0 0.0062 5.3 13 37 .. 241 264 .. 236 304 .. 0.71 4 ! 12.3 0.0 0.0002 0.17 9 61 .. 328 376 .. 324 390 .. 0.79 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0039 C2-set_3 17 irlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfe 58 +l+C++ G++P P++ W+ + +++ + ++++d+ l+ FUN_000407-T1 45 ATLKCQV-GGNPLPSITWKRNGKQVTLDSRRTIKPDG-SLYF 84 5789996.779*******9987776666666666664.3444 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0042 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpll 82 + rl C+++ +P+ +v Wr++ ++ ++ ++ +g ++++ r + +++++C+ +n++ FUN_000407-T1 140 DTARLFCNVKHSNPKAKVGWRKQGSNVSITTGDRFTLIPNGALQINNL---RFEEQGKYECFATNEIA 204 56799****************987777667777778888888888764...44667888888888776 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0062 C2-set_3 13 edggirlvCrsaGWyPePqvqWrde 37 + + l+C ++G yP+P++ W + FUN_000407-T1 241 TESTVVLECVASG-YPKPSITWLKD 264 567899***9998.********754 PP == domain 4 score: 12.3 bits; conditional E-value: 0.0002 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevet 61 v+ y++ ++ +C++aG P+P+++W +g++l+++s ++ +dg+ ev+ FUN_000407-T1 328 VHAYKKSRVQFECQAAG-IPKPNISWS-LNGRELSTSSY--TRVGDGVLEVRD 376 67899***********9.7*******7.57888888776..444557777765 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.0 7e-09 6e-06 4 47 .. 25 70 .. 22 92 .. 0.84 2 ? 0.1 0.0 1.7 1.4e+03 8 30 .. 229 251 .. 224 255 .. 0.90 3 ! 7.8 0.0 0.0064 5.4 7 42 .. 319 356 .. 314 369 .. 0.77 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 7e-09 Unc5_NetrinR_N 4 eelPifleePedayivknkpvtLkCka..akalqiyFkCngewvee 47 ++lP+f+eeP+d+y+ k+kp+tLkC++ + i +k ng++v+ FUN_000407-T1 25 ADLPHFIEEPSDTYVRKGKPATLKCQVggNPLPSITWKRNGKQVTL 70 579**********************983346678888888888765 PP == domain 2 score: 0.1 bits; conditional E-value: 1.7 Unc5_NetrinR_N 8 ifleePedayivknkpvtLkCka 30 f + P+d+ + v+L+C a FUN_000407-T1 229 SFQTRPKDTVATTESTVVLECVA 251 58899****************88 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0064 Unc5_NetrinR_N 7 PifleePedayivknkpvtLkCkaa..kalqiyFkCng 42 P+f ++P+d++ k+ v+++C+aa + +i + ng FUN_000407-T1 319 PVFTKKPSDVHAYKKSRVQFECQAAgiPKPNISWSLNG 356 9**********************972234455555555 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 9.8e-05 0.083 46 84 .. 498 536 .. 467 541 .. 0.69 2 ! 20.0 0.0 1.1e-06 0.0009 19 84 .. 567 631 .. 555 633 .] 0.81 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 9.8e-05 FN3_DSCAM-DSCAML_C 46 klviedLkpatwYelkvtAhneaGsteaeyefaTltltG 84 ++dL+p t Y+++v A+n+ G+ + e++ t++ FUN_000407-T1 498 VKQFSDLEPDTEYQFNVFAKNKHGTGAISEEITVRTYSS 536 44579*****************99887666666655555 PP == domain 2 score: 20.0 bits; conditional E-value: 1.1e-06 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTltltG 84 p++ +v+ y+ ++++e l +n+ ++++ v++dLk t+Y+++v A+ + G+ a +t+ G FUN_000407-T1 567 PVSRYVILYKDTSSNERELQDNT-KKQTRVLRDLKTYTKYTITVYAEDKDGMRGAPAVTEATTNGG 631 899*********99998887665.5666799********************988776665555554 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 8.7 7.4e+03 33 48 .. 26 41 .. 21 51 .. 0.79 2 ? 6.9 0.2 0.016 13 5 51 .. 46 106 .. 42 118 .. 0.65 3 ? 2.9 0.0 0.27 2.3e+02 31 52 .. 181 202 .. 139 213 .. 0.63 4 ! 13.4 0.0 0.00014 0.12 2 54 .. 243 305 .. 242 317 .. 0.77 5 ? 4.7 0.0 0.073 62 14 62 .. 349 406 .. 333 407 .. 0.64 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 8.7 Ig_4 33 dlgksiedprglYqCk 48 dl ++ie+p+ +Y+ k FUN_000407-T1 26 DLPHFIEEPSDTYVRK 41 78999*****999865 PP == domain 2 score: 6.9 bits; conditional E-value: 0.016 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek...........tldlgksiedprglYqCkeee 51 +L+C+ +itw+++gk+ + +++ ++ +++ + ++g+YqC++++ FUN_000407-T1 46 TLKCQVGGnplPSITWKRNGKQVTLDSRRtikpdgslyftEIFHNRTHKPDEGVYQCEGSQ 106 6888544312457999999999988887756666644442233334444789999999643 PP == domain 3 score: 2.9 bits; conditional E-value: 0.27 Ig_4 31 tldlgksiedprglYqCkeeek 52 l++++ +++g Y+C +++ FUN_000407-T1 181 ALQINNLRFEEQGKYECFATNE 202 778888888********94333 PP == domain 4 score: 13.4 bits; conditional E-value: 0.00014 Ig_4 2 dkVlLtCnsss...keitwlkdgkeikeskek.......tldlgksiedprglYqCkeeekkk 54 +V+L+C s +itwlkdg ei+ ++ +l ++++ g+Y+C+ +++++ FUN_000407-T1 243 STVVLECVASGypkPSITWLKDGFEISPGQNGysilgqgNLMIKSVAVSHAGTYTCRASQTTR 305 68*****444333368**********9998877788878889999999********9644443 PP == domain 5 score: 4.7 bits; conditional E-value: 0.073 Ig_4 14 eitwlkdgkeikeskek.....tldlgksiedprglYqCk....eeekkkssslqvyy 62 +i w +g e ++s+ + l++ + + ++g+YqC + + ++s +l vyy FUN_000407-T1 349 NISWSLNGRELSTSSYTrvgdgVLEVRDLVFSDKGVYQCFakghSGKVQASGQLFVYY 406 6777777777666665545555667777777899*****9776533555666677776 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.9 0.0 0.0098 8.3 13 33 .. 42 62 .. 31 127 .. 0.77 2 ! 11.7 0.0 0.00032 0.27 12 33 .. 241 262 .. 232 267 .. 0.80 3 ! 10.6 0.0 0.00067 0.57 8 33 .. 327 353 .. 322 363 .. 0.81 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0098 Ig_PDGFR_d4 13 sgeqtvtCvaeGmPqPeveWf 33 + t++C G P P+++W FUN_000407-T1 42 GKPATLKCQVGGNPLPSITWK 62 556799**************6 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00032 Ig_PDGFR_d4 12 ssgeqtvtCvaeGmPqPeveWf 33 +++ ++ Cva G+P+P+++W+ FUN_000407-T1 241 TESTVVLECVASGYPKPSITWL 262 44555678*************7 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00067 Ig_PDGFR_d4 8 d.shassgeqtvtCvaeGmPqPeveWf 33 d + ++++ + C a G+P+P+++W FUN_000407-T1 327 DvHAYKKSRVQFECQAAGIPKPNISWS 353 6334456677889*************7 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.0 0.0 0.00071 0.61 12 79 .. 40 102 .. 30 106 .. 0.66 2 ! 7.4 0.0 0.0089 7.6 2 43 .. 128 168 .. 127 202 .. 0.78 3 ! 10.1 0.0 0.0013 1.1 5 46 .. 234 273 .. 230 304 .. 0.73 4 ? 1.0 0.0 0.93 7.9e+02 13 44 .. 333 362 .. 320 369 .. 0.66 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00071 C1-set 12 k.gkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqllskLtvtpsewesgdeytC 79 gk++tL C v g p ++tW++ng++vt ++ +k ++s y++ + t+ + +y+C FUN_000407-T1 40 RkGKPATLKCQVGGN--PLPSITWKRNGKQVTL--DSRRTIKPDGSLYFTEIFHNRTH--KPDEGVYQC 102 33999*******985..344789*********6..66666666666666544333333..245556666 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0089 C1-set 2 yvlppspeelkgkkntLvClvtgfyPpdikVtWlkngqevte 43 v+p++++ + g+++ L C v+ P + kV W k+g++v+ FUN_000407-T1 128 DVVPKTSSVTFGDTARLFCNVKHSNP-KAKVGWRKQGSNVSI 168 56777777766**********98777.89********99985 PP == domain 3 score: 10.1 bits; conditional E-value: 0.0013 C1-set 5 ppspeelkgkkntLvClvtgfyPpdikVtWlkngqevtegvk 46 p+++ +++++++L C+++g+ p ++tWlk+g e++ g + FUN_000407-T1 234 PKDTVATTESTVVLECVASGYPKP--SITWLKDGFEISPGQN 273 677778889***********9666..679*****99998644 PP == domain 4 score: 1.0 bits; conditional E-value: 0.93 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevteg 44 ++ + C + g+ p +++W ng+e++++ FUN_000407-T1 333 KSRVQFECQAAGIPKP--NISWSLNGRELSTS 362 5555666666666444..689999****9985 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 8.4e-05 0.072 1 93 [] 445 533 .. 445 533 .. 0.71 2 ! 11.6 0.6 0.00055 0.46 10 82 .. 550 613 .. 543 628 .. 0.63 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 8.4e-05 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevys 90 Pe+v +++ + +t++ ++W +p + +++++y + + + t+ sg + ++++Lep+t+Y++ v ++n+ + se+ + FUN_000407-T1 445 PENVVAQVLS-DTEIELTWSPPGIPRGKILEYVCIYVKAGGSNVDTV-------IVSGDTLVKQFSDLEPDTEYQFNVFAKNKhgtgAISEEIT 530 6777777777.888888888887667777777776644333222222.......24677888899*************9998778888888888 PP Pur_ac_phosph_N 91 ftT 93 ++T FUN_000407-T1 531 VRT 533 777 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00055 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +++s++v+W p++ +pv +y ++++ss+ e ++++ + +l++L+ t+Y +v +e+ FUN_000407-T1 550 AvTESSIRVTWEVPDT--GPVSRYVILYKDTSSNER--------ELQDNTKKQTRVLRDLKTYTKYTITVYAED 613 55789*********86..455555555544333221........112344555667888888888888887664 PP >> Ig_Rha78A_N Rha78A-like, N-terminal immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 0.00087 0.74 17 75 .. 345 415 .. 335 420 .. 0.72 2 ? 5.9 0.0 0.024 21 17 101 .. 455 533 .. 447 535 .. 0.78 3 ? 4.5 0.2 0.07 59 15 89 .. 551 617 .. 548 629 .. 0.70 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00087 Ig_Rha78A_N 17 earPrlsWklesdergvrqtayqievass..............eeadvw.....dsgkvessesvlvpypgkpLksrt 75 ++P++sW l++ r+ + ++y +v ++ + +sgkv+ s ++ v y+g+pL +t FUN_000407-T1 345 IPKPNISWSLNG--RELSTSSYT-RVGDGvlevrdlvfsdkgvY----QcfakgHSGKVQASGQLFVYYEGEPLPVTT 415 589********9..455555554.55555555555577644430....256666********************8766 PP == domain 2 score: 5.9 bits; conditional E-value: 0.024 Ig_Rha78A_N 17 earPrlsWklesdergvrqtayqievasseeadvwdsgkvessesvlvpypgkpLksrtryywrVrvwdedgeasawsepasfet 101 +++ +l+W ++ +rg+ + + i v+ ++ + d+ v+ + lv ++ +L+++t+y++ V + +++g+ a se +++t FUN_000407-T1 455 DTEIELTWSPPGIPRGKILEYVCIYVKAGG--SNVDTVIVSGDT--LV-KQFSDLEPDTEYQFNVFAKNKHGT-GAISEEITVRT 533 567778888888888888888888888876..556666666664..55.4789******************96.88998888776 PP == domain 3 score: 4.5 bits; conditional E-value: 0.07 Ig_Rha78A_N 15 idearPrlsWklesdergvrqtayqievasseeadvwdsgkvessesvlvpypgkpLksrtryywrVrvwdedge 89 + e++ r++W++++ + y i+ +++++++++ + + ++ ++ v ++Lk t+y+++V + d+dg FUN_000407-T1 551 VTESSIRVTWEVPD---TGPVSRYVILYKDTSSNERELQDNTKK--QTRV---LRDLKTYTKYTITVYAEDKDGM 617 66788999999999...577888999999986433333333333..3333...48999**********9999994 PP >> Shr-like_HID Heme-binding protein Shr-like, Hb-interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.028 24 23 64 .. 158 196 .. 132 197 .. 0.86 2 ? 5.4 0.0 0.043 37 34 64 .. 264 297 .. 235 301 .. 0.83 3 ? 6.1 0.0 0.026 22 32 64 .. 353 386 .. 346 388 .. 0.90 4 ? -1.7 0.0 7.1 6e+03 61 70 .. 603 612 .. 597 630 .. 0.77 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.028 Shr-like_HID 23 aWrsaitevkvnGtelssdkYti.eagkitldagvftkageyt 64 Wr++ ++v++ t+ +d++t+ +g +++++ f+++g+y+ FUN_000407-T1 158 GWRKQGSNVSI--TT--GDRFTLiPNGALQINNLRFEEQGKYE 196 79999999999..44..777**9988**************996 PP == domain 2 score: 5.4 bits; conditional E-value: 0.043 Shr-like_HID 34 nGtelssdk..Yti.eagkitldagvftkageyt 64 +G e+s+++ Y+i +g++ +++ + ++ag+yt FUN_000407-T1 264 DGFEISPGQngYSIlGQGNLMIKSVAVSHAGTYT 297 77777755556****88****************8 PP == domain 3 score: 6.1 bits; conditional E-value: 0.026 Shr-like_HID 32 kvnGtelssdkYti.eagkitldagvftkageyt 64 ++nG els+++Yt +g +++ + vf+ +g y+ FUN_000407-T1 353 SLNGRELSTSSYTRvGDGVLEVRDLVFSDKGVYQ 386 58***********9999**********9999885 PP == domain 4 score: -1.7 bits; conditional E-value: 7.1 Shr-like_HID 61 geytitikAt 70 +ytit+ A+ FUN_000407-T1 603 TKYTITVYAE 612 5688888776 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.41 3.5e+02 23 42 .. 43 62 .. 33 74 .. 0.82 2 ? -2.1 0.0 6.7 5.7e+03 104 119 .. 192 207 .. 187 211 .. 0.86 3 ? 4.5 0.0 0.063 54 26 45 .. 246 265 .. 234 289 .. 0.85 4 ! 8.7 0.0 0.003 2.6 22 44 .. 333 355 .. 311 366 .. 0.78 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.41 Ig_VEGFR-1-like_5th 23 qrhkltctafgipmpnitwf 42 + l c g p+p itw FUN_000407-T1 43 KPATLKCQVGGNPLPSITWK 62 556799*************6 PP == domain 2 score: -2.1 bits; conditional E-value: 6.7 Ig_VEGFR-1-like_5th 104 sgvysctarnelgnrt 119 g y c a ne+ +t FUN_000407-T1 192 QGKYECFATNEIARKT 207 589********99887 PP == domain 3 score: 4.5 bits; conditional E-value: 0.063 Ig_VEGFR-1-like_5th 26 kltctafgipmpnitwfwqp 45 l c a g p p itw+ + FUN_000407-T1 246 VLECVASGYPKPSITWLKDG 265 589*************9765 PP == domain 4 score: 8.7 bits; conditional E-value: 0.003 Ig_VEGFR-1-like_5th 22 dqrhkltctafgipmpnitwfwq 44 r ++ c a gip pni+w + FUN_000407-T1 333 KSRVQFECQAAGIPKPNISWSLN 355 3578999*************765 PP >> Sp38 Zona-pellucida-binding protein (Sp38) N-terminal Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.88 7.5e+02 32 79 .. 59 113 .. 56 122 .. 0.65 2 ? 1.6 0.0 0.45 3.9e+02 43 79 .. 169 205 .. 153 218 .. 0.73 3 ! 10.3 0.0 0.00085 0.72 30 82 .. 257 309 .. 243 321 .. 0.83 4 ? 1.5 0.0 0.49 4.2e+02 29 74 .. 347 390 .. 335 405 .. 0.79 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.88 Sp38 32 ylWiGPdgkllsgnssinitetGelvlkd.f....eeslsGvytctls...ykivk 79 +W+ +gk+++ +s+ i + G+l +++ f +++ Gvy c s yki++ FUN_000407-T1 59 ITWK-RNGKQVTLDSRRTIKPDGSLYFTEiFhnrtHKPDEGVYQCEGSqsyYKIIS 113 5665.488999999999999999998877331111234579999964322256655 PP == domain 2 score: 1.6 bits; conditional E-value: 0.45 Sp38 43 sgnssinitetGelvlkdfeeslsGvytctlsykivk 79 + ++ + + G l +++++ + G y c+ + i + FUN_000407-T1 169 TTGDRFTLIPNGALQINNLRFEEQGKYECFATNEIAR 205 44456778899*********9********98766544 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00085 Sp38 30 PvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctlsykivkaea 82 P+ +W +++ g++ i + G+l++k s +G+ytc s + + +a FUN_000407-T1 257 PSITWLKDGFEISPGQNGYSILGQGNLMIKSVAVSHAGTYTCRASQTTRSFDA 309 66777777777888999999**********************98876655555 PP == domain 4 score: 1.5 bits; conditional E-value: 0.49 Sp38 29 dPvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctls 74 P +W +g+ ls +s+ ++ G l ++d+ s Gvy c+ + FUN_000407-T1 347 KPNISWS-LNGRELSTSSYTRVG-DGVLEVRDLVFSDKGVYQCFAK 390 5777775.589999999999986.599999***999*******865 PP >> DUF4998 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.2 1e-06 0.00089 82 188 .. 506 609 .. 457 614 .. 0.88 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1e-06 DUF4998 82 eEgsytfeivtydkkgnsSvavevsaevYGdsYqssLtnrslksaelekkeltikwskvekeaklvkteleYtnkagetktvrikkkeeqtkltdf 177 + y+f++++++k+g ++ e++ +Y +s + r l++ +++++++ ++w+ + + + + Y++++ ++++++ + k+++ +l d FUN_000407-T1 506 PDTEYQFNVFAKNKHGTGAISEEITVRTYSSSAVPG-KPRDLVAEAVTESSIRVTWEVPDTGP-VSRYVILYKDTSSNERELQDNTKKQTRVLRDL 599 5678*************************8875554.89*******************99999.99****************************** PP DUF4998 178 kpgtsfkyrtv 188 k t++++ tv FUN_000407-T1 600 KTYTKYTI-TV 609 *9999987.44 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 1.8 1.6e+03 49 89 .. 59 107 .. 46 121 .. 0.61 2 ? 4.6 0.1 0.046 39 28 93 .. 140 206 .. 116 217 .. 0.72 3 ! 10.2 0.0 0.00081 0.69 27 101 .. 242 315 .. 227 326 .. 0.67 4 ? -1.0 0.0 2.4 2.1e+03 44 65 .. 345 366 .. 333 402 .. 0.61 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.8 V-set_CD47 49 vkWkfnnkdifisnktekkst..........LkldfsdalsGnYtCevtel 89 + Wk+n+k+++ + + ++ +G Y Ce ++ FUN_000407-T1 59 ITWKRNGKQVTLDSRRTI--KpdgslyfteiFHNRTHKPDEGVYQCEGSQS 107 788888888876554422..2345555554222223334478888887655 PP == domain 2 score: 4.6 bits; conditional E-value: 0.046 V-set_CD47 28 dtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst....Lkldfsd.alsGnYtCevtelsnev 93 dt + C+v++ + ++ v W+ +++++ i + + + + L++++ + +G Y C +t++ + FUN_000407-T1 140 DTARLFCNVKH----SNPKAKVGWRKQGSNVSITTGDRFTLIpngaLQINNLRfEEQGKYECFATNEIARK 206 67778899966....446788*******99999988855555888866665441458*****999876543 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00081 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst.....Lkld.fsdalsGnYtCevtelsnevkttieLkl 101 +tvv+eC + ++ + W ++ +i ++ s+ L ++ + +G+YtC +++++++ t +L + FUN_000407-T1 242 ESTVVLECVASGYPKP-----SITWLKDGFEISPGQNGY--SIlgqgnLMIKsVAVSHAGTYTCRASQTTRSFDATAKLDV 315 5778888877664444.....457777777776544432..222355544441455679***************9999987 PP == domain 4 score: -1.0 bits; conditional E-value: 2.4 V-set_CD47 44 isevyvkWkfnnkdifisnkte 65 i++ ++W++n++++ +s t+ FUN_000407-T1 345 IPKPNISWSLNGRELSTSSYTR 366 4555679999999988877664 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.11 92 42 86 .. 473 518 .. 454 529 .. 0.81 2 ! 13.7 0.1 9.6e-05 0.081 43 88 .. 570 614 .. 552 625 .. 0.84 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.11 Interfer-bind 42 lqYkvsywknssnkekkelestnelv.vlsdLepnteYCvsVqaes 86 l+Y +y k + ++ ++++ s +lv +sdLep teY ++V a++ FUN_000407-T1 473 LEYVCIYVKAGGSNVDTVIVSGDTLVkQFSDLEPDTEYQFNVFAKN 518 67888888888776777777666655169*********99998843 PP == domain 2 score: 13.7 bits; conditional E-value: 9.6e-05 Interfer-bind 43 qYkvsywknssnkekkelestnelvvlsdLepnteYCvsVqaesrk 88 Y + y +ssn+++ + ++++++ vl+dL+ t+Y ++V+a ++k FUN_000407-T1 570 RYVILYKDTSSNERELQDNTKKQTRVLRDLKTYTKYTITVYA-EDK 614 699*********7777777777778*****************.444 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.8 0.0 0.00032 0.27 83 112 .. 491 520 .. 425 533 .. 0.86 2 ? 4.5 0.0 0.055 47 85 111 .. 588 614 .. 543 628 .. 0.75 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00032 NDNF 83 vCvgkktvqtvseLkpdtqYyfdvFavdqk 112 + g++ v +s+L+pdt+Y f+vFa +++ FUN_000407-T1 491 IVSGDTLVKQFSDLEPDTEYQFNVFAKNKH 520 44577778889***************9986 PP == domain 2 score: 4.5 bits; conditional E-value: 0.055 NDNF 85 vgkktvqtvseLkpdtqYyfdvFavdq 111 kk+ ++++Lk t+Y ++v+a d+ FUN_000407-T1 588 NTKKQTRVLRDLKTYTKYTITVYAEDK 614 556777889**************9876 PP >> InlK_D3 Internalin K domain (D3/D4) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.39 3.3e+02 45 74 .. 503 532 .. 493 533 .. 0.88 2 ! 12.5 0.1 0.0002 0.17 45 68 .. 598 621 .. 579 625 .. 0.88 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.39 InlK_D3 45 dlntpGdYtVtLnAededgnkaepveVtVt 74 dl+ +Y+ ++ A++++g+ a + e+tV+ FUN_000407-T1 503 DLEPDTEYQFNVFAKNKHGTGAISEEITVR 532 6667789*****************999995 PP == domain 2 score: 12.5 bits; conditional E-value: 0.0002 InlK_D3 45 dlntpGdYtVtLnAededgnkaep 68 dl+t +Yt+t++Aed+dg+ +p FUN_000407-T1 598 DLKTYTKYTITVYAEDKDGMRGAP 621 899*****************9988 PP >> Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.012 9.9 11 85 .. 455 524 .. 442 531 .. 0.69 2 ? 5.7 0.1 0.042 36 44 82 .. 545 581 .. 528 589 .. 0.68 3 ? 5.9 0.1 0.035 30 9 41 .. 552 583 .. 542 618 .. 0.55 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.012 Kre9_KNH 11 gspvtitWsdsptdp......gtvtlvLvngssnnlksvktiasgisnssgsytwtvpsdleagegYqlqivsesekntgi 85 +++++tW sp + v +++ +g s +v+t++ + sg + ++ sdle++++Yq+++ ++++++tg+ FUN_000407-T1 455 DTEIELTW--SPPGIprgkilEYVCIYVKAGGS----NVDTVI--V---SGDTLVKQFSDLEPDTEYQFNVFAKNKHGTGA 524 35588888..33333367777777777777755....333433..2...677778889****************9877765 PP == domain 2 score: 5.7 bits; conditional E-value: 0.042 Kre9_KNH 44 ktiasgisnssgsytwtvpsdleagegYqlqivsesekn 82 + +a++++ ss +tw vp + + ++ Y + +++s +n FUN_000407-T1 545 DLVAEAVTESSIRVTWEVPDTGPVSR-YVILYKDTS-SN 581 45568888888888888855555544.888777777.34 PP == domain 3 score: 5.9 bits; conditional E-value: 0.035 Kre9_KNH 9 dagspvtitWsdsptdpgtvtlvLvngssnnlk 41 + s++ +tW+ +t p + ++L++ +s+n FUN_000407-T1 552 TE-SSIRVTWEVPDTGPVSRYVILYKDTSSNER 583 22.446666655555555555555555443333 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.32 2.7e+02 41 92 .. 152 199 .. 132 217 .. 0.67 2 ? 9.0 0.0 0.002 1.7 68 93 .. 276 301 .. 236 313 .. 0.83 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.32 Ig_6 41 kdksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 + k +V W +q ++ i+ + aL+++ ++ ++ G Y C FUN_000407-T1 152 NPKAKVGWRKQGSNV----SITTGDRFTLIPNGALQINNLRFEEQGKYECFA 199 555666665544432....344444445567889999999999*****9975 PP == domain 2 score: 9.0 bits; conditional E-value: 0.002 Ig_6 68 iileknaLrfkpvkvndsGlYiCrpr 93 il + +L +k+v v+++G+Y Cr FUN_000407-T1 276 SILGQGNLMIKSVAVSHAGTYTCRAS 301 5677899****************953 PP >> Ig_J Tip attachment protein J, Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 3.7 3.1e+03 70 90 .. 501 522 .. 457 535 .. 0.73 2 ? 12.1 0.2 0.00026 0.22 27 97 .. 555 624 .. 532 629 .. 0.73 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 3.7 Ig_J 70 lseL.plGkytltvrakneeGq 90 +s+L p +y+ v akn++G FUN_000407-T1 501 FSDLePDTEYQFNVFAKNKHGT 522 4555245678888888888874 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00026 Ig_J 27 qvrakWdtprvvkgvsFelkltveeddsdrlvsrattsdteyrlseLp.lGkytltvrakneeGqqGeeasv 97 +r++W+ p + ++ + l ++ +s++ +++t+ ++ +l++L+ kyt+tv a +++G +G +a + FUN_000407-T1 555 SIRVTWEVPDTGPVSRY-VILYKD-TSSNERELQDNTKKQTRVLRDLKtYTKYTITVYAEDKDGMRGAPAVT 624 58999999998655555.556554.344455556666777778899962689****************9976 PP >> DUF6788 Domain of unknown function (DUF6788) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.00015 0.13 22 56 .. 35 69 .. 15 70 .. 0.77 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00015 DUF6788 22 veeyrrcGkpnc.kcareghgpYwYlywregGktks 56 y+r+Gkp kc g++p + +w+ +Gk+++ FUN_000407-T1 35 SDTYVRKGKPATlKCQ-VGGNPLPSITWKRNGKQVT 69 34589****8884666.78**************986 PP >> fn3_4 Fibronectin-III type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.18 1.5e+02 2 24 .. 441 463 .. 440 477 .. 0.93 2 ? -1.2 0.0 3.1 2.7e+03 72 93 .. 500 521 .. 496 528 .. 0.85 3 ? 5.4 0.0 0.027 23 2 61 .. 539 598 .. 538 620 .. 0.81 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.18 fn3_4 2 pPqkpelkiakvevptgivlsWn 24 P+kpe +a+v ++t+i l+W FUN_000407-T1 441 FPEKPENVVAQVLSDTEIELTWS 463 69********************6 PP == domain 2 score: -1.2 bits; conditional E-value: 3.1 fn3_4 72 tlsqfkegkkyyfavrakDiyg 93 ++s++++++ y+f v ak +g FUN_000407-T1 500 QFSDLEPDTEYQFNVFAKNKHG 521 5789999**********99987 PP == domain 3 score: 5.4 bits; conditional E-value: 0.027 fn3_4 2 pPqkpelkiakvevptgivlsWnvekldpkaaevesYelflyqeetktssstdsWkkigd 61 +P kp+ +a+ ++++i ++W+v+++ p+ v Y+ ++e++ + +++++ + + d FUN_000407-T1 539 VPGKPRDLVAEAVTESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDNTKKQTRVLRD 598 68899989999999*************999999999987777777776666665555555 PP >> Cadherin Cadherin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.39 3.4e+02 40 92 .. 166 218 .. 146 219 .. 0.69 2 ? 2.6 0.0 0.31 2.7e+02 60 89 .. 503 532 .. 496 533 .. 0.87 3 ? 5.0 0.1 0.053 45 58 86 .. 598 624 .. 548 629 .. 0.70 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.39 Cadherin 40 e....ggnFridpetgdisttkpLDrEergeYeLtveatdssgspplsstatvtitV 92 + g+ F++ p +g ++++ +L Ee+g+Ye + at++ + + +st+ +++V FUN_000407-T1 166 VsittGDRFTLIP-NGALQIN-NLRFEEQGKYE--CFATNEIARKTHTSTTVGNVKV 218 4445567788888.7888887.9*********8..6788884455566666556665 PP == domain 2 score: 2.6 bits; conditional E-value: 0.31 Cadherin 60 DrEergeYeLtveatdssgspplsstatvt 89 D E eY+++v a+++ g+ + s++ tv+ FUN_000407-T1 503 DLEPDTEYQFNVFAKNKHGTGAISEEITVR 532 678899***********9999999888875 PP == domain 3 score: 5.0 bits; conditional E-value: 0.053 Cadherin 58 pLDrEergeYeLtveatdssgspplssta 86 L ++ +Y++tv+a+d++g ++ +++ FUN_000407-T1 598 DLK--TYTKYTITVYAEDKDGMRGAPAVT 624 333..489***********7666555544 PP >> Y_Y_Y Y_Y_Y domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.028 24 39 57 .. 509 527 .. 509 534 .. 0.81 2 ? 4.1 0.0 0.074 63 39 51 .. 604 616 .. 602 627 .. 0.87 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.028 Y_Y_Y 39 kYtlkVkakdkdgnweydd 57 +Y++ V+ak+k g+ + ++ FUN_000407-T1 509 EYQFNVFAKNKHGTGAISE 527 7************988764 PP == domain 2 score: 4.1 bits; conditional E-value: 0.074 Y_Y_Y 39 kYtlkVkakdkdg 51 kYt++V+a dkdg FUN_000407-T1 604 KYTITVYAEDKDG 616 7**********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (633 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 838 (0.0328049); expected 510.9 (0.02) Passed bias filter: 717 (0.0280681); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 30 (0.0011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 30 [number of targets reported over threshold] # CPU time: 0.40u 0.37s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 6229.55 // Query: FUN_000407-T2 [L=991] Description: FUN_000407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-65 215.7 10.7 9e-14 51.9 0.0 6.6 6 fn3 Fibronectin type III domain 1.8e-58 195.0 0.3 7.7e-14 52.0 0.0 5.6 5 I-set Immunoglobulin I-set domain 4.8e-58 194.1 4.3 2.2e-15 57.4 0.0 5.6 5 Ig_3 Immunoglobulin domain 3.7e-40 136.5 3.1 2.8e-11 44.0 0.0 4.6 4 Ig_2 Immunoglobulin domain 1e-29 103.1 7.8 8.9e-07 29.6 0.1 5.4 4 ig Immunoglobulin domain 2.7e-23 82.6 0.1 0.0017 19.1 0.0 5.5 5 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 5.4e-18 65.3 0.1 0.00097 19.6 0.0 4.9 4 C2-set_2 CD80-like C2-set immunoglobulin domain 1.3e-14 54.8 12.0 0.0071 17.0 0.1 8.5 6 V-set Immunoglobulin V-set domain 1.5e-13 51.6 10.6 0.084 14.0 0.0 7.5 6 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal doma 2.5e-10 41.0 0.8 0.13 12.8 0.0 4.5 4 NDNF Neuron-derived neurotrophic factor, firs 1.6e-09 38.4 0.0 6.2e-06 26.9 0.0 3.6 3 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 5.5e-09 36.4 0.1 2.9 8.4 0.0 4.4 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 4.1e-08 33.8 0.1 0.42 11.1 0.0 4.0 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor 5.6e-08 33.3 0.2 0.15 12.7 0.0 4.8 5 Fn3_VIN3 VIN3-like, fibronectin type-III domain 9.4e-08 33.0 0.2 0.22 12.6 0.0 5.3 4 Ig_4 T-cell surface glycoprotein CD3 delta ch 8e-07 29.8 0.2 1.5 9.7 0.0 4.8 4 C1-set Immunoglobulin C1-set domain 3.3e-06 27.9 0.1 0.96 10.2 0.0 4.2 4 ASTN1_2_fn3 ASTN1/2 Fn3 domain 7.9e-06 26.6 0.4 0.14 12.9 0.1 4.8 5 Interfer-bind Interferon-alpha/beta receptor, fibronec 7.2e-05 22.9 3.6 0.0049 16.9 0.8 3.3 3 DUF4998 Domain of unknown function 8.3e-05 22.9 0.4 0.33 11.3 0.1 2.6 2 Monellin Monellin 0.0015 19.2 0.0 3.8 8.2 0.0 4.0 3 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.003 17.9 0.5 41 4.6 0.0 5.7 6 fn3_4 Fibronectin-III type domain 0.0042 18.3 9.8 55 5.1 0.1 6.3 5 Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain 0.0043 17.3 0.2 1.4 9.2 0.0 3.5 3 V-set_CD47 CD47 immunoglobulin-like domain 0.006 17.1 0.3 1.9 9.0 0.0 3.5 3 Ig_J_second Tip attachment protein J second Ig-like 0.0089 16.4 2.1 21 5.6 0.1 4.1 4 Y_Y_Y Y_Y_Y domain 0.0094 16.9 0.0 44 5.1 0.0 4.4 4 Shr-like_HID Heme-binding protein Shr-like, Hb-intera ------ inclusion threshold ------ 0.016 15.8 2.3 0.38 11.4 0.2 3.6 3 Ig_J Tip attachment protein J, Ig-like domain 0.019 15.4 0.1 1.3 9.5 0.0 3.4 3 Sp38 Zona-pellucida-binding protein (Sp38) N- 0.019 15.5 2.0 0.29 11.7 0.1 3.3 3 InlK_D3 Internalin K domain (D3/D4) 0.031 14.8 0.5 70 4.0 0.0 4.2 4 Ig_ILCR1 ILCR1 Ig-like domain 0.032 14.5 0.0 0.083 13.2 0.0 1.6 1 SNCAIP_SNCA_bd Synphilin-1 alpha-Synuclein-binding doma 0.036 15.0 1.2 82 4.2 0.1 4.6 4 Cadherin Cadherin domain 0.13 12.6 0.0 2.9 8.2 0.0 2.6 2 Ig_6 Immunoglobulin domain 8.9 7.2 9.8 77 4.2 0.0 4.2 4 DUF1410 Protein of unknown function (DUF1410) Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.1 0.1 9.4e-16 6.8e-13 2 83 .. 443 530 .. 442 531 .. 0.87 2 ! 49.9 0.4 5.3e-16 3.9e-13 2 77 .. 541 617 .. 540 624 .. 0.88 3 ! 33.1 0.1 9.1e-11 6.7e-08 2 78 .. 635 719 .. 634 724 .. 0.86 4 ! 23.5 0.0 8.9e-08 6.5e-05 14 75 .. 751 819 .. 739 828 .. 0.81 5 ! 51.9 0.0 1.2e-16 9e-14 2 83 .. 869 956 .. 868 957 .. 0.92 6 ! 9.2 0.0 0.0026 1.9 2 23 .. 967 988 .. 966 991 .] 0.90 Alignments for each domain: == domain 1 score: 49.1 bits; conditional E-value: 9.4e-16 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+n+ ++ ++t+++++W+pp ++g+i +Y y ++++ v+g++ ++++L+p+teY+++V a n++G g se+++v FUN_000407-T2 443 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVKAGGsnvdtvIVSGDTlV--KQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTV 530 7******99999***********99*************88886665555555332..568**************************9987 PP == domain 2 score: 49.9 bits; conditional E-value: 5.3e-16 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne...tvpgsr.etsvtltgLkpgteYevrVqavngaGegee 77 +P++l +++vt++s++v+W+ pd gp+++Y + y+++++ ++++++ +++ l++Lk +t+Y+++V+a ++G ++ FUN_000407-T2 541 KPRDLVAEAVTESSIRVTWEVPD-TGPVSRYVILYKDTSSnerELQDNTkKQTRVLRDLKTYTKYTITVYAEDKDG--MR 617 7*********************5.9************76677****9998777889***************98875..44 PP == domain 3 score: 33.1 bits; conditional E-value: 9.1e-11 fn3 2 aPtnltvt.dvtstsltvsWtpp...dgngpitgYeveyrp.kne....tvpgsretsvtltgLkpgteYevrVqavngaGegees 78 P+n++++ d + t l +Wt p ++ng+++ Y ++yr+ ne ++ + ++ +t+++L g Ye +++a ++ G g+++ FUN_000407-T2 635 TPRNFSLKpDSSGTALIATWTVPdptRVNGKVSFYIIKYRKqINEqttsRIGAD-KSAFTISNLMTGVIYEAKIAAGSNSGLGQYT 719 59*****98999999***********9**************6444334455555.788******************9999999876 PP == domain 4 score: 23.5 bits; conditional E-value: 8.9e-08 fn3 14 tsltvsWtpp..dgngpitgYeveyrpkne.......tvpgsretsvtltgLkpgteYevrVqavngaGeg 75 + + v+W pp +tgY + ++ +n+ ++++ ++ + +++L+p++ Y +++ a n+aG+g FUN_000407-T2 751 NAILVRWLPPdnADLVCVTGYLL-WWGENTpfhfsagPLSKD-HNHYLIKNLRPNQMYYLKLVANNSAGNG 819 7899******432234455**99.777788788888888888.899***********************98 PP == domain 5 score: 51.9 bits; conditional E-value: 1.2e-16 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+n+ ++ ++t+++++W+pp ++g+i +Y y ++++ +v+g++ t+++L+p+teY+++V a n++G g se++++ FUN_000407-T2 869 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVKAGGsnvdrvNVSGDTlV--RTFSDLEPDTEYQFNVFAKNKHGTGAISEEVKA 956 7******99999***********99*************88888898999999553..89**************************99875 PP == domain 6 score: 9.2 bits; conditional E-value: 0.0026 fn3 2 aPtnltvtdvtstsltvsWtpp 23 +P++l +++vt++s++v+W p FUN_000407-T2 967 KPRDLAAEAVTESSIRVTWVVP 988 7******************998 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.5 0.0 4.8e-14 3.5e-11 1 88 [. 28 118 .. 28 120 .. 0.86 2 ! 41.6 0.0 1.9e-13 1.4e-10 2 85 .. 126 209 .. 125 213 .. 0.85 3 ! 52.0 0.0 1.1e-16 7.7e-14 2 90 .] 229 315 .. 228 315 .. 0.94 4 ! 50.8 0.0 2.4e-16 1.8e-13 1 90 [] 319 403 .. 319 403 .. 0.92 5 ? -2.3 0.0 9.4 6.8e+03 12 38 .. 537 563 .. 502 581 .. 0.69 Alignments for each domain: == domain 1 score: 43.5 bits; conditional E-value: 4.8e-14 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee..gtatLtIsnvkkeDeGkYtckatns.ageaeasaeL 88 p+f ++++d+ v++ + a+l+c+v G+p p+++W+++g++++ ++r +k ++ ++++ ++ k DeG+Y+c+ + s ++ + +a++ FUN_000407-T2 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTLDSRRTIKPDGslYFTEIFHNRTHKPDEGIYQCEGSQSyYKIISRTARV 118 89***************************************************555556666889999*******9888744444555555 PP == domain 2 score: 41.6 bits; conditional E-value: 1.9e-13 I-set 2 kftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselke..skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 k++ +k ++v+ G++a+l c+v+ + p+ +v W k+gs+++ ++r+ + ++ L I+n++ e++GkY+c atn++ +++++ FUN_000407-T2 126 KVDVVPKTLSVTFGDTARLFCNVKHSnPKAKVGWRKQGSNVSIttGDRFTLIPNG---ALQINNLRFEEQGKYECFATNEIARKTHT 209 567789*****************9655**********776655338888888888...9*********************8777665 PP == domain 3 score: 52.0 bits; conditional E-value: 1.1e-16 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +f+ ++kd+ +++++++ lec +sG p+p+++Wlkdg e+++ ++ +++ ++ L+I++v + +G+Ytc+a+ + + a+a+L V FUN_000407-T2 229 SFQARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPgQNGYSILGQG---NLMIKSVAVSHAGTYTCRASQTTRSFDATAKLDV 315 69999*************************************66678888888...**************************99999987 PP == domain 4 score: 50.8 bits; conditional E-value: 2.4e-16 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p ft+k++dv + ++++++ec+++G p+p++sW+ +g+el+ ++ ++ L+++++ +D+G Y+c a+ +g+++as +L V FUN_000407-T2 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSL--SYTRVVDG---VLEVRDLVFSDKGVYQCFAKGHSGKVQASGQLFV 403 78****************************************5..34444444...9***************************999876 PP == domain 5 score: -2.3 bits; conditional E-value: 9.4 I-set 12 vkeGesaeleckvsGepepevsWlkdg 38 + G+ +l +++ e ++v+W + FUN_000407-T2 537 AVPGKPRDLVAEAVTESSIRVTWEVPD 563 445566666666667777777777665 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.3 0.1 7.2e-14 5.2e-11 2 76 .. 28 104 .. 28 105 .. 0.78 2 ! 39.6 0.0 1.1e-12 8e-10 6 78 .] 129 201 .. 126 201 .. 0.84 3 ! 57.4 0.0 3e-18 2.2e-15 5 77 .. 231 301 .. 225 301 .. 0.90 4 ! 49.8 0.0 7.1e-16 5.2e-13 2 77 .. 319 389 .. 318 389 .. 0.94 5 ? -0.5 0.1 3.5 2.5e+03 11 51 .. 535 576 .. 527 607 .. 0.65 Alignments for each domain: == domain 1 score: 43.3 bits; conditional E-value: 7.2e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskrsssssnstLtisnvtredsGtYtCvA 76 P + +ps+t v++ +++tL+C++ gnp p+itW++ngk+ l+s +t k s + +++ +++++ d+G Y+C+ FUN_000407-T2 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQvtLDSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEG 104 778889*********************************764333333322555555555555699*********85 PP == domain 2 score: 39.6 bits; conditional E-value: 1.1e-12 Ig_3 6 vspsstvveegesvtLtCea.egnppptitWykngke..lssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 v p++ +v+ g++++L C++ ++np+ ++ W+k+g++ +++ + n+ L+i+n+++e +G+Y+C A+N FUN_000407-T2 129 VVPKTLSVTFGDTARLFCNVkHSNPKAKVGWRKQGSNvsITT-----GdrFTLIPNGALQINNLRFEEQGKYECFATN 201 5577777999**********7777777*********653333.....23379*************************9 PP == domain 3 score: 57.4 bits; conditional E-value: 3e-18 Ig_3 5 tvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 ++ p++t+++ ++v+L+C a+g+p+p+itW+k+g e+s+g+ +s ++++L i++v +++GtYtC+As FUN_000407-T2 231 QARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNG--YSILGQGNLMIKSVAVSHAGTYTCRAS 301 47789999****************************98886666..79***********************97 PP == domain 4 score: 49.8 bits; conditional E-value: 7.1e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 Pv+t +ps++++ +++v+++C+aeg p+p+i+W+ ng+ + s s ++ ++L+++++ ++d G Y+C A+ FUN_000407-T2 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGR---ELSLS--YTRVVDGVLEVRDLVFSDKGVYQCFAK 389 9**************************************...66666..57899*******************995 PP == domain 5 score: -0.5 bits; conditional E-value: 3.5 Ig_3 11 tvveegesvtLtCeaegnppptitWykngkelssgstskr...s 51 +++++g++ L ea +++ ++tW +++ ++s++ FUN_000407-T2 535 SSAVPGKPRDLVAEAVTESSIRVTWEVPDT--GPVSRYVIlykD 576 445788888888888777777999999888..343333335432 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.8 0.1 4.3e-14 3.2e-11 5 79 .] 33 120 .. 29 120 .. 0.88 2 ! 23.1 0.1 1.3e-07 9.3e-05 11 74 .. 136 210 .. 126 218 .. 0.75 3 ! 44.0 0.0 3.9e-14 2.8e-11 5 67 .. 233 304 .. 229 315 .. 0.88 4 ! 22.7 0.0 1.7e-07 0.00012 6 71 .. 325 395 .. 318 403 .. 0.77 Alignments for each domain: == domain 1 score: 43.8 bits; conditional E-value: 4.3e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn............fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++s+t v+++++ tL+C++ gnp +++tw ++gk + +s++ +f+++ + d G+Y+C+ +++ ++ s++ ++tv FUN_000407-T2 33 EPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTlDSRRtikpdgslyfteIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3666899**************************99888555557777889777777799**************************998 PP == domain 2 score: 23.1 bits; conditional E-value: 1.3e-07 Ig_2 11 vtegesvtLtCsas.gnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnp 74 vt g++ +L C ++ +np+ak+ w+k+g+ +s ++ + + ++n e +G Y C a+n+ k+ + FUN_000407-T2 136 VTFGDTARLFCNVKhSNPKAKVGWRKQGSNVSiTTGDrftlipngaLQINNLRFEEQGKYECFATNEIARKTHTS 210 7889*********999************9999844444544444434468899************9666554444 PP == domain 3 score: 44.0 bits; conditional E-value: 3.9e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn.........fftsnvsaedsGtYtCtarntk 67 ++ +t t+ ++v L C asg p++++tw kdg ++s++qn + +++v ++++GtYtC+a++t FUN_000407-T2 233 RPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNgysilgqgnLMIKSVAVSHAGTYTCRASQTT 304 4555778999*******************************999999988889***************9864 PP == domain 4 score: 22.7 bits; conditional E-value: 1.7e-07 Ig_2 6 asptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn.....fftsnvsaedsGtYtCtarntkggkv 71 +s+ + +++ v++ C+a g p+++++w +g++ls s+++ + ++ +d+G+Y+C a+ ++ gkv FUN_000407-T2 325 PSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSlSYTRvvdgvLEVRDLVFSDKGVYQCFAKGHS-GKV 395 44477899****************************88888555533356688*********998544.554 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.1 1.2e-09 8.9e-07 3 71 .. 37 105 .. 35 108 .. 0.86 2 ! 27.7 0.1 4.7e-09 3.4e-06 2 74 .. 133 203 .. 132 209 .. 0.90 3 ! 24.2 0.1 5.8e-08 4.2e-05 8 73 .. 242 303 .. 237 310 .. 0.91 4 ! 21.8 0.0 3.4e-07 0.00025 5 79 .. 330 397 .. 326 398 .. 0.92 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 1.2e-09 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk.vkedngrttqssllisnvteedaGtYtCvvn 71 ++v++++ atL C + g+p p++tW+++gk+ ++ ++ + + +g+ + +++ +++ + d+G Y C+++ FUN_000407-T2 37 TYVRKSKPATLKCQVG-GNPLPSITWKRNGKQVTLDSRrTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGS 105 789999**********.*********************64444455555589999999*********997 PP == domain 2 score: 27.7 bits; conditional E-value: 4.7e-09 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 t+ v G++a+L C++++++p + v W+k+g+ ++ + ++ + + l+i+n ++e G Y C ++n+ FUN_000407-T2 133 TLSVTFGDTARLFCNVKHSNPKAKVGWRKQGSNVSITTG--DRFTLIPNGALQINNLRFEEQGKYECFATNEI 203 67899*************************998777766..778888888*******************9975 PP == domain 3 score: 24.2 bits; conditional E-value: 5.8e-08 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++++L C as g p p++tW k+g ++ ++ ++ +q +l i +v ++aGtYtC+++ + FUN_000407-T2 242 ESTVVLECVAS-GYPKPSITWLKDGFEISPGQN---GYSILGQGNLMIKSVAVSHAGTYTCRASQT 303 689********.*************99999988...88888999******************9865 PP == domain 4 score: 21.8 bits; conditional E-value: 3.4e-07 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 +++ +++++ C a+ g p p+++Ws +g ++ +s + r+ + l +++ ++d G Y C + ++g++++ FUN_000407-T2 330 AYRNSRVRFECQAE-GIPKPNISWSLNGRELSLSYT------RVVDGVLEVRDLVFSDKGVYQCFAKGHSGKVQA 397 678899********.***************999955......*************************99999887 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 0.0 0.00051 0.37 46 85 .. 497 536 .. 467 540 .. 0.70 2 ! 19.1 0.0 2.4e-06 0.0017 19 83 .. 566 629 .. 554 636 .. 0.81 3 ! 13.0 0.0 0.00019 0.14 20 72 .. 666 717 .. 661 728 .. 0.84 4 ! 16.7 0.0 1.4e-05 0.01 42 85 .. 790 834 .. 775 837 .. 0.77 5 ! 14.5 0.0 6.4e-05 0.047 20 85 .. 897 962 .. 886 966 .. 0.78 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00051 FN3_DSCAM-DSCAML_C 46 klviedLkpatwYelkvtAhneaGsteaeyefaTltltGa 85 ++dL+p t Y++ v A+n+ G+ + e++ t++ + FUN_000407-T2 497 VKQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTVRTYSSS 536 44579*****************999877666666666554 PP == domain 2 score: 19.1 bits; conditional E-value: 2.4e-06 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTltlt 83 p++ +v+ y+ ++++e l +n+ ++++ v++dLk t+Y+++v A+ + G+ a +t+ FUN_000407-T2 566 PVSRYVILYKDTSSNERELQDNT-KKQTRVLRDLKTYTKYTITVYAEDKDGMRGAPAVTEATTNG 629 899*********99998887665.5666799*******************998877665555554 PP == domain 3 score: 13.0 bits; conditional E-value: 0.00019 FN3_DSCAM-DSCAML_C 20 ilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGste 72 ++++ ++yrk+ +e+ ++ + ++ ++i++L+ + Ye k++A ++ G + FUN_000407-T2 666 VSFYIIKYRKQINEQTTS-RIGADKSAFTISNLMTGVIYEAKIAAGSNSGLGQ 717 7899*****999887665.34567889*********************99765 PP == domain 4 score: 16.7 bits; conditional E-value: 1.4e-05 FN3_DSCAM-DSCAML_C 42 keqeklviedLkpatwYelkvtAhneaGst.eaeyefaTltltGa 85 k +++++i++L+p ++Y lk+ A+n+aG + ++ +T +G+ FUN_000407-T2 790 KDHNHYLIKNLRPNQMYYLKLVANNSAGNGlDVQIITQTAPADGE 834 5678899*********************86234555555556665 PP == domain 5 score: 14.5 bits; conditional E-value: 6.4e-05 FN3_DSCAM-DSCAML_C 20 ilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTltltGa 85 il +v y k+g ++ v+ + + +++dL+p t Y+++v A+n+ G+ + e++ t++ + FUN_000407-T2 897 ILEYVCIYVKAGGSNVDRVNVSGDTLVRTFSDLEPDTEYQFNVFAKNKHGTGAISEEVKARTYSSS 962 666666677777676666766667777889*******************99888777777776655 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 1.2e-05 0.0091 15 72 .. 43 97 .. 30 105 .. 0.75 2 ! 7.9 0.0 0.006 4.4 14 45 .. 139 169 .. 127 194 .. 0.77 3 ! 19.6 0.0 1.3e-06 0.00097 5 41 .. 234 268 .. 231 307 .. 0.82 4 ! 14.8 0.0 4.2e-05 0.031 10 44 .. 328 362 .. 319 370 .. 0.78 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 1.2e-05 C2-set_2 15 kevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredn 72 k +++C gg+P p+itW ++gk++ + ++++++p+ l+ + + ++ ++++ d FUN_000407-T2 43 KPATLKC-QVGGNPLPSITWKRNGKQV-TLDSRRTIKPDGSLYFT-EIFHNRTHKPDE 97 5678899.679***************9.77777777777777766.788888777665 PP == domain 2 score: 7.9 bits; conditional E-value: 0.006 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaae 45 + + + C ++ ++P++++ W ++g ++ ++ FUN_000407-T2 139 GDTARLFCNVKHSNPKAKVGWRKQGSNV-SIT 169 4567778******************998.333 PP == domain 3 score: 19.6 bits; conditional E-value: 1.3e-06 C2-set_2 5 psaslleaeekevvatCvsaggkPapritWlldgkel 41 p++++ ++e +vv++C +a+g+P+p+itWl+dg e+ FUN_000407-T2 234 PKDTMATTE-STVVLEC-VASGYPKPSITWLKDGFEI 268 455555565.99*****.899************9776 PP == domain 4 score: 14.8 bits; conditional E-value: 4.2e-05 C2-set_2 10 leae.ekevvatCvsaggkPapritWlldgkeleaa 44 + a + +v ++C a+g P+p+i+W l+g+el+ + FUN_000407-T2 328 VHAYrNSRVRFEC-QAEGIPKPNISWSLNGRELSLS 362 4444678999***.999***************9443 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.3 0.0072 5.3 59 108 .. 71 120 .. 32 121 .. 0.64 2 ! 14.8 0.1 4.6e-05 0.034 3 98 .. 131 208 .. 129 219 .. 0.72 3 ! 17.0 0.1 9.7e-06 0.0071 59 108 .. 272 315 .. 232 316 .. 0.78 4 ? -0.5 0.0 2.6 1.9e+03 2 36 .. 324 355 .. 323 365 .. 0.85 5 ! 8.9 0.0 0.0033 2.4 69 104 .. 365 399 .. 355 404 .. 0.73 6 ? 0.3 0.0 1.5 1.1e+03 25 61 .. 551 587 .. 530 608 .. 0.74 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0072 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + r +++ d s +++ + + D+G+Y+C+ +++ +++ r+tV FUN_000407-T2 71 DSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3333333334455555666678889********65555555999999988 PP == domain 2 score: 14.8 bits; conditional E-value: 4.6e-05 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekk.kgrfslrkdpsrsdfsltiqnltlsDsGtYtCav...ip 94 p++++v G +++L C ++ s ++ +v W +q ++ ++++ ++rf+l ++ l+i+nl+ + +G Y+C + i+ FUN_000407-T2 131 PKTLSVTFGDTARLFCNVKHS--NPKAKVGWRKQGSN---------------VSITtGDRFTLIP-----NGALQINNLRFEEQGKYECFAtneIA 204 778888888888888877755..78888888887754...............3444499******.....*******************9533333 PP V-set 95 kgev 98 ++++ FUN_000407-T2 205 RKTH 208 3333 PP == domain 3 score: 17.0 bits; conditional E-value: 9.7e-06 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 ++ +s+ + + l i+++ +s++GtYtC+ ++ + +f ++ +L V FUN_000407-T2 272 QNGYSILG-----QGNLMIKSVAVSHAGTYTCR-ASQTTRSFDATAKLDV 315 55666666.....99******************.8999999999998877 PP == domain 4 score: -0.5 bits; conditional E-value: 2.6 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrq 36 +p+ v++ ++ +v++ C+ + ++W+ FUN_000407-T2 324 KPSDVHAYRNSRVRFECQAEGI---PKPNISWSLN 355 68999************98887...9999999875 PP == domain 5 score: 8.9 bits; conditional E-value: 0.0033 V-set 69 srsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 + d+ l++++l sD G+Y+C + + +++ +++ FUN_000407-T2 365 RVVDGVLEVRDLVFSDKGVYQCFA-KGHSGKVQASG 399 566999****************94.44444444444 PP == domain 6 score: 0.3 bits; conditional E-value: 1.5 V-set 25 seasqsvyWyrqppgkepteliayysnkseeekkkgr 61 +e s +v+W ++g ++++i+y ++s+e ++ FUN_000407-T2 551 TESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDN 587 4578899****99998888888888885555444444 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 0.00017 0.12 1 93 [] 444 532 .. 444 532 .. 0.71 2 ! 10.8 0.6 0.0012 0.84 10 82 .. 549 612 .. 542 627 .. 0.63 3 ? 2.6 0.0 0.42 3e+02 1 65 [. 636 707 .. 636 718 .. 0.64 4 ! 8.4 0.0 0.0064 4.7 57 83 .. 789 815 .. 768 824 .. 0.83 5 ! 14.0 0.0 0.00011 0.084 1 93 [] 870 958 .. 870 958 .. 0.70 6 ? 1.2 0.0 1.1 7.8e+02 6 23 .. 971 989 .. 968 991 .] 0.80 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00017 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevys 90 Pe+v +++ + +t++ ++W +p + +++++y + + + t+ sg + ++++Lep+t+Y++ v ++n+ + se+ + FUN_000407-T2 444 PENVVAQVLS-DTEIELTWSPPGIPRGKILEYVCIYVKAGGSNVDTV-------IVSGDTLVKQFSDLEPDTEYQFYVFAKNKhgtgAISEEVT 529 6777777777.888888888887667777777766644333222222.......24677788899*************9998778888888888 PP Pur_ac_phosph_N 91 ftT 93 ++T FUN_000407-T2 530 VRT 532 877 PP == domain 2 score: 10.8 bits; conditional E-value: 0.0012 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +++s++v+W p++ +pv +y ++++ss+ e ++++ + +l++L+ t+Y +v +e+ FUN_000407-T2 549 AvTESSIRVTWEVPDT--GPVSRYVILYKDTSSNER--------ELQDNTKKQTRVLRDLKTYTKYTITVYAED 612 55789*********86..455555555543333221........112344555667888888888888887664 PP == domain 3 score: 2.6 bits; conditional E-value: 0.42 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeat.tsp.....vvqygtsssa.lsstatatsstyttedltsgyihsatl 65 P + l + ++ t+++ +W+ p++t + +++y+++ ++ ++s+ a+ s++t ++l +g i++a++ FUN_000407-T2 636 PRNFSLKPDSSGTALIATWTVPDPTrVNGkvsfyIIKYRKQINEqTTSRIGADKSAFTISNLMTGVIYEAKI 707 5666777777899999*****975423333444455555554443444555566666666667777777766 PP == domain 4 score: 8.4 bits; conditional E-value: 0.0064 Pur_ac_phosph_N 57 sgyihsatltgLepgttYyYrvgdens 83 s ++++++++L p++ Yy + ++ns FUN_000407-T2 789 SKDHNHYLIKNLRPNQMYYLKLVANNS 815 56789***************9988874 PP == domain 5 score: 14.0 bits; conditional E-value: 0.00011 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevys 90 Pe+v +++ + +t++ ++W +p + +++++y + + ++++ + + sg + t+++Lep+t+Y++ v ++n+ + se+ + FUN_000407-T2 870 PENVVAQVLS-DTEIELTWSPPGIPRGKILEYVCIYVKA----GGSNV---DRVNVSGDTLVRTFSDLEPDTEYQFNVFAKNKhgtgAISEEVK 955 6777777777.8888888888876677777776666332....22222...1334678888899**************9998767777777766 PP Pur_ac_phosph_N 91 ftT 93 +T FUN_000407-T2 956 ART 958 665 PP == domain 6 score: 1.2 bits; conditional E-value: 1.1 Pur_ac_phosph_N 6 lsltg.pstsmtvsWrtpe 23 l+ + +++s++v+W+ p+ FUN_000407-T2 971 LAAEAvTESSIRVTWVVPD 989 56667789*******9886 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.002 1.5 84 113 .. 491 520 .. 428 533 .. 0.86 2 ? 3.7 0.0 0.11 83 85 111 .. 587 613 .. 543 627 .. 0.75 3 ! 9.8 0.0 0.0016 1.1 88 115 .. 792 819 .. 789 829 .. 0.84 4 ! 12.8 0.0 0.00018 0.13 86 112 .. 919 945 .. 891 955 .. 0.88 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.002 NDNF 84 CvgkktvqtvseLkpdtqYyfdvFavdqkr 113 g++ v +s+L+pdt+Y f vFa +++ FUN_000407-T2 491 VSGDTLVKQFSDLEPDTEYQFYVFAKNKHG 520 4577777889***************99875 PP == domain 2 score: 3.7 bits; conditional E-value: 0.11 NDNF 85 vgkktvqtvseLkpdtqYyfdvFavdq 111 kk+ ++++Lk t+Y ++v+a d+ FUN_000407-T2 587 NTKKQTRVLRDLKTYTKYTITVYAEDK 613 456777889**************9876 PP == domain 3 score: 9.8 bits; conditional E-value: 0.0016 NDNF 88 ktvqtvseLkpdtqYyfdvFavdqkrnt 115 ++++++++L+p++ Yy+ + a ++ n FUN_000407-T2 792 HNHYLIKNLRPNQMYYLKLVANNSAGNG 819 799****************998887665 PP == domain 4 score: 12.8 bits; conditional E-value: 0.00018 NDNF 86 gkktvqtvseLkpdtqYyfdvFavdqk 112 g++ v t+s+L+pdt+Y f+vFa +++ FUN_000407-T2 919 GDTLVRTFSDLEPDTEYQFNVFAKNKH 945 677789*****************9976 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.0 8.6e-09 6.2e-06 4 46 .. 25 69 .. 22 87 .. 0.83 2 ? -0.5 0.0 3 2.2e+03 9 30 .. 230 251 .. 224 254 .. 0.90 3 ? 6.3 0.0 0.022 16 7 31 .. 319 343 .. 315 368 .. 0.86 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 8.6e-09 Unc5_NetrinR_N 4 eelPifleePedayivknkpvtLkCka..akalqiyFkCngewve 46 ++lP+f+eeP+d+y+ k+kp+tLkC++ + i +k ng++v+ FUN_000407-T2 25 ADLPHFIEEPSDTYVRKSKPATLKCQVggNPLPSITWKRNGKQVT 69 579**********************98334667888888888876 PP == domain 2 score: -0.5 bits; conditional E-value: 3 Unc5_NetrinR_N 9 fleePedayivknkpvtLkCka 30 f P+d+ + v+L+C a FUN_000407-T2 230 FQARPKDTMATTESTVVLECVA 251 8899****************88 PP == domain 3 score: 6.3 bits; conditional E-value: 0.022 Unc5_NetrinR_N 7 PifleePedayivknkpvtLkCkaa 31 P+f ++P+d++ +n v ++C+a+ FUN_000407-T2 319 PVFTKKPSDVHAYRNSRVRFECQAE 343 9**********************96 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.0 0.0064 4.7 15 57 .. 43 83 .. 36 102 .. 0.74 2 ! 7.3 0.0 0.0086 6.3 15 82 .. 140 204 .. 133 209 .. 0.78 3 ? 7.0 0.0 0.011 7.9 13 37 .. 241 264 .. 235 304 .. 0.72 4 ! 8.4 0.0 0.004 2.9 9 42 .. 328 359 .. 324 384 .. 0.80 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0064 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglf 57 + +l+C++ G++P P++ W+ + +++ + ++++d+ l+ FUN_000407-T2 43 KPATLKCQV-GGNPLPSITWKRNGKQVTLDSRRTIKPDG-SLY 83 556899996.779*******9987776666666666664.344 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0086 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpll 82 + rl C+++ +P+ +v Wr++ ++ ++ ++ +g ++++ r + +++++C+ +n++ FUN_000407-T2 140 DTARLFCNVKHSNPKAKVGWRKQGSNVSITTGDRFTLIPNGALQINNL---RFEEQGKYECFATNEIA 204 56799****************987777667777778888888888764...44667888888888775 PP == domain 3 score: 7.0 bits; conditional E-value: 0.011 C2-set_3 13 edggirlvCrsaGWyPePqvqWrde 37 + + l+C ++G yP+P++ W + FUN_000407-T2 241 TESTVVLECVASG-YPKPSITWLKD 264 567899***9998.********754 PP == domain 4 score: 8.4 bits; conditional E-value: 0.004 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekgekl 42 v+ y++ +r +C+++G P+P+++W + g++l FUN_000407-T2 328 VHAYRNSRVRFECQAEG-IPKPNISWSLN-GREL 359 678999*********99.7*******754.4444 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.011 8.4 11 33 .. 40 62 .. 30 136 .. 0.75 2 ! 11.1 0.0 0.00058 0.42 12 33 .. 241 262 .. 232 266 .. 0.79 3 ! 10.7 0.0 0.00074 0.54 9 33 .. 329 353 .. 322 357 .. 0.79 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.011 Ig_PDGFR_d4 11 assgeqtvtCvaeGmPqPeveWf 33 +s+ t++C G P P+++W FUN_000407-T2 40 RKSKPATLKCQVGGNPLPSITWK 62 56777899**************6 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00058 Ig_PDGFR_d4 12 ssgeqtvtCvaeGmPqPeveWf 33 +++ ++ Cva G+P+P+++W+ FUN_000407-T2 241 TESTVVLECVASGYPKPSITWL 262 44555678*************6 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00074 Ig_PDGFR_d4 9 shassgeqtvtCvaeGmPqPeveWf 33 + +++ C aeG+P+P+++W FUN_000407-T2 329 HAYRNSRVRFECQAEGIPKPNISWS 353 34456677789*************7 PP >> Fn3_VIN3 VIN3-like, fibronectin type-III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.027 19 60 80 .. 500 520 .. 478 532 .. 0.81 2 ? -0.7 0.1 3.1 2.3e+03 30 74 .. 569 609 .. 546 616 .. 0.55 3 ? -1.0 0.0 3.9 2.8e+03 31 73 .. 669 707 .. 655 714 .. 0.71 4 ! 12.7 0.0 0.0002 0.15 27 80 .. 767 817 .. 745 826 .. 0.88 5 ! 7.3 0.0 0.0096 7 59 80 .. 925 946 .. 914 958 .. 0.81 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.027 Fn3_VIN3 60 isgLePateYvfkvvsfnetr 80 s+LeP+teY f v + n+++ FUN_000407-T2 500 FSDLEPDTEYQFYVFAKNKHG 520 689*********998877654 PP == domain 2 score: -0.7 bits; conditional E-value: 3.1 Fn3_VIN3 30 gYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvv 74 Y + ++ ++ +e + + +++ v+++L+ t+Y++ v FUN_000407-T2 569 RYVILYKDTSSNERELQD----NTKKQTRVLRDLKTYTKYTITVY 609 455555444333333332....23455567889999999988774 PP == domain 3 score: -1.0 bits; conditional E-value: 3.9 Fn3_VIN3 31 YkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkv 73 Y + +rk + +++ t+++ a+++ f+is+L Y k+ FUN_000407-T2 669 YIIKYRK----QINEQTTSRIGADKSAFTISNLMTGVIYEAKI 707 4444444....56778889999999999999997666666555 PP == domain 4 score: 12.7 bits; conditional E-value: 0.0002 Fn3_VIN3 27 kivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvvsfnetr 80 ++gY Lw+ ++ +++a p l +++++++i++L+P+ Y++k+v+ n+++ FUN_000407-T2 767 CVTGYLLWWGENTPFHFSAGP---LSKDHNHYLIKNLRPNQMYYLKLVANNSAG 817 5899****9999999999888...678999******************999876 PP == domain 5 score: 7.3 bits; conditional E-value: 0.0096 Fn3_VIN3 59 visgLePateYvfkvvsfnetr 80 + s+LeP+teY f v + n+++ FUN_000407-T2 925 TFSDLEPDTEYQFNVFAKNKHG 946 5789***********9877655 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.1 0.027 20 5 51 .. 46 106 .. 42 118 .. 0.65 2 ? 2.0 0.0 0.62 4.5e+02 31 52 .. 181 202 .. 140 213 .. 0.66 3 ! 12.6 0.0 0.0003 0.22 2 54 .. 243 305 .. 242 317 .. 0.77 4 ? 4.9 0.0 0.079 57 5 62 .. 337 405 .. 333 406 .. 0.69 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.027 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek...........tldlgksiedprglYqCkeee 51 +L+C+ +itw+++gk+ + +++ ++ +++ + ++g+YqC++++ FUN_000407-T2 46 TLKCQVGGnplPSITWKRNGKQVTLDSRRtikpdgslyftEIFHNRTHKPDEGIYQCEGSQ 106 67885443124579999999999888877566666444422333344457899****9643 PP == domain 2 score: 2.0 bits; conditional E-value: 0.62 Ig_4 31 tldlgksiedprglYqCkeeek 52 l++++ +++g Y+C +++ FUN_000407-T2 181 ALQINNLRFEEQGKYECFATNE 202 6788888889*******94333 PP == domain 3 score: 12.6 bits; conditional E-value: 0.0003 Ig_4 2 dkVlLtCnsss...keitwlkdgkeikeskek.......tldlgksiedprglYqCkeeekkk 54 +V+L+C s +itwlkdg ei+ ++ +l ++++ g+Y+C+ +++++ FUN_000407-T2 243 STVVLECVASGypkPSITWLKDGFEISPGQNGysilgqgNLMIKSVAVSHAGTYTCRASQTTR 305 68*****444333368**********9998877788878889999999********9644443 PP == domain 4 score: 4.9 bits; conditional E-value: 0.079 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek....tldlgksiedprglYqCk....eeekkkssslqvyy 62 +C+ + +i w +g e + s ++ l++ + + ++g+YqC + + ++s +l vyy FUN_000407-T2 337 RFECQAEGipkPNISWSLNGRELSLSYTRvvdgVLEVRDLVFSDKGVYQCFakghSGKVQASGQLFVYY 405 55665443322578899999998888888777778888888899******9776533555666677776 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.0 0.002 1.5 12 61 .. 41 86 .. 30 106 .. 0.66 2 ? 4.9 0.0 0.066 48 4 43 .. 130 168 .. 127 202 .. 0.75 3 ! 8.7 0.0 0.0041 3 5 46 .. 234 273 .. 230 304 .. 0.72 4 ? -1.2 0.0 5.2 3.8e+03 13 43 .. 333 361 .. 320 367 .. 0.65 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.002 C1-set 12 kgkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqll 61 k+k++tL C v g p ++tW++ng++vt ++ +k ++s y++ FUN_000407-T2 41 KSKPATLKCQVGGN--PLPSITWKRNGKQVTL--DSRRTIKPDGSLYFTE 86 3899*******984..344789*********6..6666666666666654 PP == domain 2 score: 4.9 bits; conditional E-value: 0.066 C1-set 4 lppspeelkgkkntLvClvtgfyPpdikVtWlkngqevte 43 +p++ + + g+++ L C v+ P + kV W k+g++v+ FUN_000407-T2 130 VPKTLSVTFGDTARLFCNVKHSNP-KAKVGWRKQGSNVSI 168 555555555999*******98777.89********99985 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0041 C1-set 5 ppspeelkgkkntLvClvtgfyPpdikVtWlkngqevtegvk 46 p+++ +++++++L C+++g+ p ++tWlk+g e++ g + FUN_000407-T2 234 PKDTMATTESTVVLECVASGYPKP--SITWLKDGFEISPGQN 273 5555666799**********9666..679*****99998644 PP == domain 4 score: -1.2 bits; conditional E-value: 5.2 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevte 43 ++ + C ++g+ p +++W ng+e++ FUN_000407-T2 333 NSRVRFECQAEGIPKP--NISWSLNGRELSL 361 5556666777776444..6789999999875 PP >> ASTN1_2_fn3 ASTN1/2 Fn3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.01 7.5 89 123 .] 498 532 .. 471 532 .. 0.82 2 ? -1.4 0.0 5.5 4e+03 80 115 .. 586 619 .. 573 625 .. 0.73 3 ! 10.2 0.0 0.0013 0.96 13 78 .. 645 713 .. 637 741 .. 0.71 4 ? 4.5 0.0 0.081 59 88 123 .] 923 958 .. 898 958 .. 0.79 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.01 ASTN1_2_fn3 89 vifkclePdalykftlyavdnrGrrsesstvsvrt 123 f lePd+ y+f ++a +++G + s +v+vrt FUN_000407-T2 498 KQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTVRT 532 45777****************************98 PP == domain 2 score: -1.4 bits; conditional E-value: 5.5 ASTN1_2_fn3 80 dvpekqlisvifkclePdalykftlyavdnrGrrse 115 d ++kq + +++ l+ + y t+ya d+ G r FUN_000407-T2 586 DNTKKQ--TRVLRDLKTYTKYTITVYAEDKDGMRGA 619 444443..56788888999999*******9998765 PP == domain 3 score: 10.2 bits; conditional E-value: 0.0013 ASTN1_2_fn3 13 PsstvvaleWldvePl.iGvkvsdyilq.hkkvedrtdaevytgevlsfvddllsGlksscvva.grsa 78 s t + W+ +P+ + kvs yi++ +k+++++t + + ++++ + +l+ G+ + +a g ++ FUN_000407-T2 645 SSGTALIATWTVPDPTrVNGKVSFYIIKyRKQINEQTTSRIGADKSAFTISNLMTGVIYEAKIAaGSNS 713 46677778899999964899*******934679*************999*******9876654404443 PP == domain 4 score: 4.5 bits; conditional E-value: 0.081 ASTN1_2_fn3 88 svifkclePdalykftlyavdnrGrrsesstvsvrt 123 f lePd+ y+f ++a +++G + s +v rt FUN_000407-T2 923 VRTFSDLEPDTEYQFNVFAKNKHGTGAISEEVKART 958 456778******************999888888876 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.5 3.6e+02 42 85 .. 472 516 .. 467 531 .. 0.76 2 ! 12.9 0.1 0.0002 0.14 43 88 .. 569 613 .. 552 624 .. 0.84 3 ? 0.6 0.0 1.3 9.5e+02 44 78 .. 669 703 .. 661 714 .. 0.88 4 ? -1.5 0.0 6.1 4.4e+03 62 83 .. 790 811 .. 786 818 .. 0.77 5 ? 3.6 0.0 0.15 1.1e+02 42 86 .. 898 943 .. 891 954 .. 0.76 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.5 Interfer-bind 42 lqYkvsywknssnkekkelestnelv.vlsdLepnteYCvsVqae 85 l+Y +y k + ++ ++++ s +lv +sdLep teY + V a+ FUN_000407-T2 472 LEYVCIYVKAGGSNVDTVIVSGDTLVkQFSDLEPDTEYQFYVFAK 516 67888888888776777776666655169*********9888773 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0002 Interfer-bind 43 qYkvsywknssnkekkelestnelvvlsdLepnteYCvsVqaesrk 88 Y + y +ssn+++ + ++++++ vl+dL+ t+Y ++V+a ++k FUN_000407-T2 569 RYVILYKDTSSNERELQDNTKKQTRVLRDLKTYTKYTITVYA-EDK 613 699*********7777777777778*****************.444 PP == domain 3 score: 0.6 bits; conditional E-value: 1.3 Interfer-bind 44 YkvsywknssnkekkelestnelvvlsdLepnteY 78 Y + y+k+ ++++++++ ++ +++s+L + Y FUN_000407-T2 669 YIIKYRKQINEQTTSRIGADKSAFTISNLMTGVIY 703 9999*****99999**************9988776 PP == domain 4 score: -1.5 bits; conditional E-value: 6.1 Interfer-bind 62 stnelvvlsdLepnteYCvsVq 83 + ++ + +++L+pn+ Y ++ FUN_000407-T2 790 KDHNHYLIKNLRPNQMYYLKLV 811 5677889********9976655 PP == domain 5 score: 3.6 bits; conditional E-value: 0.15 Interfer-bind 42 lqYkvsywknssn.kekkelestnelvvlsdLepnteYCvsVqaes 86 l+Y +y k + + ++ ++++ + ++sdLep teY ++V a++ FUN_000407-T2 898 LEYVCIYVKAGGSnVDRVNVSGDTLVRTFSDLEPDTEYQFNVFAKN 943 67888888887662555566666667799*********99998843 PP >> DUF4998 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.8 6.7e-06 0.0049 82 188 .. 505 608 .. 468 614 .. 0.88 2 ? 0.8 0.0 0.59 4.3e+02 149 183 .. 669 703 .. 640 707 .. 0.82 3 ? 3.3 0.0 0.099 73 82 111 .. 931 960 .. 901 985 .. 0.86 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 6.7e-06 DUF4998 82 eEgsytfeivtydkkgnsSvavevsaevYGdsYqssLtnrslksaelekkeltikwskvekeaklvkteleYtnkagetktvrikkkeeqtkltdf 177 + y+f +++++k+g ++ ev+ +Y +s + r l++ +++++++ ++w+ + + + + Y++++ ++++++ + k+++ +l d FUN_000407-T2 505 PDTEYQFYVFAKNKHGTGAISEEVTVRTYSSSAVPG-KPRDLVAEAVTESSIRVTWEVPDTGP-VSRYVILYKDTSSNERELQDNTKKQTRVLRDL 598 5678*************************8875554.89*******************99999.99****************************** PP DUF4998 178 kpgtsfkyrtv 188 k t++++ tv FUN_000407-T2 599 KTYTKYTI-TV 608 *9999987.44 PP == domain 2 score: 0.8 bits; conditional E-value: 0.59 DUF4998 149 teleYtnkagetktvrikkkeeqtkltdfkpgtsf 183 ++Y ++ +e++t ri +++++ ++++ g + FUN_000407-T2 669 YIIKYRKQINEQTTSRIGADKSAFTISNLMTGVIY 703 5689**********************998866554 PP == domain 3 score: 3.3 bits; conditional E-value: 0.099 DUF4998 82 eEgsytfeivtydkkgnsSvavevsaevYG 111 + y+f++++++k+g ++ ev a +Y FUN_000407-T2 931 PDTEYQFNVFAKNKHGTGAISEEVKARTYS 960 5678***********************996 PP >> Monellin Monellin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.1 0.00045 0.33 7 32 .. 508 533 .. 506 535 .. 0.93 2 ! 9.0 0.0 0.0024 1.8 7 32 .. 934 959 .. 932 961 .. 0.94 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00045 Monellin 7 diqlyvYasdkLfkadvdEdyKirqr 32 ++q yv+a +k + +++E+ +r + FUN_000407-T2 508 EYQFYVFAKNKHGTGAISEEVTVRTY 533 9*******************999987 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0024 Monellin 7 diqlyvYasdkLfkadvdEdyKirqr 32 ++q v+a +k + +++E+ K r + FUN_000407-T2 934 EYQFNVFAKNKHGTGAISEEVKARTY 959 89*********************998 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.64 4.7e+02 20 42 .. 40 62 .. 33 77 .. 0.83 2 ? 4.0 0.0 0.1 76 26 45 .. 246 265 .. 227 302 .. 0.86 3 ! 8.2 0.0 0.0052 3.8 20 47 .. 332 358 .. 312 370 .. 0.78 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.64 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwf 42 r + l c g p+p itw FUN_000407-T2 40 RKSKPATLKCQVGGNPLPSITWK 62 455566799*************6 PP == domain 2 score: 4.0 bits; conditional E-value: 0.1 Ig_VEGFR-1-like_5th 26 kltctafgipmpnitwfwqp 45 l c a g p p itw+ + FUN_000407-T2 246 VLECVASGYPKPSITWLKDG 265 689*************9765 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0052 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwfwqpcd 47 r + r ++ c a gip pni+w + + FUN_000407-T2 332 R-NSRVRFECQAEGIPKPNISWSLNGRE 358 3.568999**************876655 PP >> fn3_4 Fibronectin-III type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.35 2.6e+02 2 24 .. 440 462 .. 439 474 .. 0.93 2 ? -1.5 0.0 4.6 3.4e+03 72 93 .. 499 520 .. 495 528 .. 0.83 3 ? 4.6 0.0 0.057 41 2 60 .. 538 596 .. 537 618 .. 0.81 4 ? -1.0 0.0 3.2 2.3e+03 15 47 .. 646 677 .. 635 688 .. 0.69 5 ? 2.1 0.0 0.34 2.5e+02 2 24 .. 866 888 .. 865 905 .. 0.93 6 ? -0.6 0.0 2.4 1.7e+03 71 93 .. 924 946 .. 910 954 .. 0.85 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.35 fn3_4 2 pPqkpelkiakvevptgivlsWn 24 P+kpe +a+v ++t+i l+W FUN_000407-T2 440 FPEKPENVVAQVLSDTEIELTWS 462 69********************6 PP == domain 2 score: -1.5 bits; conditional E-value: 4.6 fn3_4 72 tlsqfkegkkyyfavrakDiyg 93 ++s++++++ y+f v ak +g FUN_000407-T2 499 QFSDLEPDTEYQFYVFAKNKHG 520 5788999999999999999887 PP == domain 3 score: 4.6 bits; conditional E-value: 0.057 fn3_4 2 pPqkpelkiakvevptgivlsWnvekldpkaaevesYelflyqeetktssstdsWkkig 60 +P kp+ +a+ ++++i ++W+v+++ p+ v Y+ ++e++ + +++++ + + FUN_000407-T2 538 VPGKPRDLVAEAVTESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDNTKKQTRVLR 596 68899989999999*************99999999998777777776666665555555 PP == domain 4 score: -1.0 bits; conditional E-value: 3.2 fn3_4 15 vptgivlsWnvekldpkaaevesYelflyqeet 47 + t + +W+v++ ++ +v+ Y + y+ ++ FUN_000407-T2 646 SGTALIATWTVPDPTRVNGKVSFYIIK-YRKQI 677 66788889****999999999877663.33333 PP == domain 5 score: 2.1 bits; conditional E-value: 0.34 fn3_4 2 pPqkpelkiakvevptgivlsWn 24 P+kpe +a+v ++t+i l+W FUN_000407-T2 866 FPEKPENVVAQVLSDTEIELTWS 888 69********************6 PP == domain 6 score: -0.6 bits; conditional E-value: 2.4 fn3_4 71 ctlsqfkegkkyyfavrakDiyg 93 t+s++++++ y+f v ak +g FUN_000407-T2 924 RTFSDLEPDTEYQFNVFAKNKHG 946 58999**************9987 PP >> Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.18 1.3e+02 11 85 .. 454 523 .. 441 530 .. 0.68 2 ? 5.1 0.1 0.075 55 44 82 .. 544 580 .. 525 591 .. 0.69 3 ? 3.3 0.2 0.27 2e+02 11 89 .. 647 719 .. 640 722 .. 0.68 4 ? 0.5 0.0 2 1.5e+03 27 67 .. 805 846 .. 791 849 .. 0.80 5 ? 5.0 0.0 0.08 59 50 85 .. 915 949 .. 867 952 .. 0.65 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.18 Kre9_KNH 11 gspvtitWsdsptdp......gtvtlvLvngssnnlksvktiasgisnssgsytwtvpsdleagegYqlqivsesekntgi 85 +++++tW sp + v +++ +g s +v+t++ + sg + ++ sdle++++Yq+ + ++++++tg+ FUN_000407-T2 454 DTEIELTW--SPPGIprgkilEYVCIYVKAGGS----NVDTVI--V---SGDTLVKQFSDLEPDTEYQFYVFAKNKHGTGA 523 35588888..33333367777777777777755....333333..2...6777788889**********999999877765 PP == domain 2 score: 5.1 bits; conditional E-value: 0.075 Kre9_KNH 44 ktiasgisnssgsytwtvpsdleagegYqlqivsesekn 82 + +a++++ ss +tw vp + + ++ Y + +++s +n FUN_000407-T2 544 DLVAEAVTESSIRVTWEVPDTGPVSR-YVILYKDTS-SN 580 55668888888888888855555444.888777777.34 PP == domain 3 score: 3.3 bits; conditional E-value: 0.27 Kre9_KNH 11 gspvtitWsdsptdp...gtvtlvLvng.ssnnlksvktiasgisnssgsytwtvpsdleagegYqlqivsesekntgiynyS 89 g+++ tW ++p+ g+v++++++ ++ n ++ s i +++ +t++ +l +g Y +i+++s n+g +y+ FUN_000407-T2 647 GTALIATW-TVPDPTrvnGKVSFYIIKYrKQINEQTT----SRIGADKSAFTIS---NLMTGVIYEAKIAAGS--NSGLGQYT 719 6667789*.444333699*********9444444444....4454545556665...7999999999999999..56666665 PP == domain 4 score: 0.5 bits; conditional E-value: 2 Kre9_KNH 27 tvtlvLvng.ssnnlksvktiasgisnssgsytwtvpsdlea 67 + l+Lv++ s++n +v+ i+++ +++++ +t p+++++ FUN_000407-T2 805 MYYLKLVANnSAGNGLDVQIITQTAPADGEPLPVTTPATTPP 846 566888888788889999999999999888888888887776 PP == domain 5 score: 5.0 bits; conditional E-value: 0.08 Kre9_KNH 50 isnssgsytwtvpsdleagegYqlqivsesekntgi 85 ++ sg + + sdle++++Yq+++ ++++++tg+ FUN_000407-T2 915 VNV-SGDTLVRTFSDLEPDTEYQFNVFAKNKHGTGA 949 333.5555566679**************99888775 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.2 0.11 84 28 92 .. 140 205 .. 46 217 .. 0.82 2 ! 9.2 0.0 0.0019 1.4 27 101 .. 242 315 .. 228 326 .. 0.67 3 ? -1.2 0.0 3.3 2.4e+03 27 61 .. 333 362 .. 315 398 .. 0.69 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.11 V-set_CD47 28 dtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst....Lkldfsd.alsGnYtCevtelsne 92 dt + C+v++ + ++ v W+ +++++ i + + + + L++++ + +G Y C +t++ + FUN_000407-T2 140 DTARLFCNVKH----SNPKAKVGWRKQGSNVSITTGDRFTLIpngaLQINNLRfEEQGKYECFATNEIAR 205 56677888866....4467889999999999998888555558888666554314589999999887653 PP == domain 2 score: 9.2 bits; conditional E-value: 0.0019 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst.....Lkld.fsdalsGnYtCevtelsnevkttieLkl 101 +tvv+eC + ++ + W ++ +i ++ s+ L ++ + +G+YtC +++++++ t +L + FUN_000407-T2 242 ESTVVLECVASGYPKP-----SITWLKDGFEISPGQNGY--SIlgqgnLMIKsVAVSHAGTYTCRASQTTRSFDATAKLDV 315 5677777777664444.....457777777665544432..222355544441455679***************9999987 PP == domain 3 score: -1.2 bits; conditional E-value: 3.3 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifis 61 n+ v eC+ + +++ ni +W++n++++ s FUN_000407-T2 333 NSRVRFECQAEGIPKPNI-----SWSLNGRELSLS 362 777888888877666655.....999999877655 PP >> Ig_J_second Tip attachment protein J second Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.0027 1.9 54 86 .. 492 524 .. 484 536 .. 0.85 2 ? 0.5 0.0 1.2 8.8e+02 63 83 .. 798 818 .. 789 830 .. 0.81 3 ? 2.6 0.0 0.26 1.9e+02 55 88 .. 919 952 .. 910 964 .. 0.75 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0027 Ig_J_second 54 tgklwtkegknlkpdktyyfYvRtvnayGkSaF 86 +g++++k+ ++l+pd++y fYv ++n+ G+ a FUN_000407-T2 492 SGDTLVKQFSDLEPDTEYQFYVFAKNKHGTGAI 524 6788899999*******************8765 PP == domain 2 score: 0.5 bits; conditional E-value: 1.2 Ig_J_second 63 knlkpdktyyfYvRtvnayGk 83 knl+p++ yy + + n+ G+ FUN_000407-T2 798 KNLRPNQMYYLKLVANNSAGN 818 48*********9999999886 PP == domain 3 score: 2.6 bits; conditional E-value: 0.26 Ig_J_second 55 gklwtkegknlkpdktyyfYvRtvnayGkSaFve 88 g++++ + ++l+pd++y f v ++n+ G+ a e FUN_000407-T2 919 GDTLVRTFSDLEPDTEYQFNVFAKNKHGTGAISE 952 5556666678******************977654 PP >> Y_Y_Y Y_Y_Y domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.1 0.029 21 39 57 .. 508 526 .. 508 533 .. 0.81 2 ? 3.4 0.0 0.14 1e+02 39 51 .. 603 615 .. 601 626 .. 0.87 3 ? -1.7 0.0 5.5 4e+03 11 38 .. 667 700 .. 665 716 .. 0.82 4 ? 3.6 0.0 0.12 88 39 54 .. 934 949 .. 931 955 .. 0.87 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.029 Y_Y_Y 39 kYtlkVkakdkdgnweydd 57 +Y+++V+ak+k g+ + ++ FUN_000407-T2 508 EYQFYVFAKNKHGTGAISE 526 7***********9988764 PP == domain 2 score: 3.4 bits; conditional E-value: 0.14 Y_Y_Y 39 kYtlkVkakdkdg 51 kYt++V+a dkdg FUN_000407-T2 603 KYTITVYAEDKDG 615 7**********98 PP == domain 3 score: -1.7 bits; conditional E-value: 5.5 Y_Y_Y 11 rYrlegfdgeWvelgdys......eisytnlppG 38 ++ ++++ ++ e + ++ ++++nl G FUN_000407-T2 667 SFYIIKYRKQINEQTTSRigadksAFTISNLMTG 700 5668899999998888888888888899888766 PP == domain 4 score: 3.6 bits; conditional E-value: 0.12 Y_Y_Y 39 kYtlkVkakdkdgnwe 54 +Y++ V+ak+k g+ + FUN_000407-T2 934 EYQFNVFAKNKHGTGA 949 7**********99876 PP >> Shr-like_HID Heme-binding protein Shr-like, Hb-interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.06 44 23 64 .. 158 196 .. 137 197 .. 0.87 2 ? 4.6 0.0 0.09 66 34 64 .. 264 297 .. 236 301 .. 0.84 3 ? 0.3 0.0 2 1.4e+03 32 63 .. 353 384 .. 348 386 .. 0.86 4 ? -1.4 0.0 6.5 4.8e+03 62 70 .. 603 611 .. 591 648 .. 0.58 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.06 Shr-like_HID 23 aWrsaitevkvnGtelssdkYti.eagkitldagvftkageyt 64 Wr++ ++v++ t+ +d++t+ +g +++++ f+++g+y+ FUN_000407-T2 158 GWRKQGSNVSI--TT--GDRFTLiPNGALQINNLRFEEQGKYE 196 69999999999..44..777**9988**************996 PP == domain 2 score: 4.6 bits; conditional E-value: 0.09 Shr-like_HID 34 nGtelssdk..Yti.eagkitldagvftkageyt 64 +G e+s+++ Y+i +g++ +++ + ++ag+yt FUN_000407-T2 264 DGFEISPGQngYSIlGQGNLMIKSVAVSHAGTYT 297 67776755556****88****************8 PP == domain 3 score: 0.3 bits; conditional E-value: 2 Shr-like_HID 32 kvnGtelssdkYti.eagkitldagvftkagey 63 ++nG els + Yt +g +++ + vf+ +g y FUN_000407-T2 353 SLNGRELSLS-YTRvVDGVLEVRDLVFSDKGVY 384 579***9999.887789**********999988 PP == domain 4 score: -1.4 bits; conditional E-value: 6.5 Shr-like_HID 62 eytitikAt 70 +ytit+ A+ FUN_000407-T2 603 KYTITVYAE 611 344444443 PP >> Ig_J Tip attachment protein J, Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.2 0.00052 0.38 27 98 .. 554 624 .. 532 630 .. 0.73 2 ? 2.1 0.0 0.4 2.9e+02 5 89 .. 627 714 .. 623 721 .. 0.73 3 ? -2.0 0.0 7.4 5.4e+03 70 89 .. 926 946 .. 882 953 .. 0.69 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00052 Ig_J 27 qvrakWdtprvvkgvsFelkltveeddsdrlvsrattsdteyrlseLp.lGkytltvrakneeGqqGeeasvs 98 +r++W+ p + ++ + l ++ +s++ +++t+ ++ +l++L+ kyt+tv a +++G +G +a ++ FUN_000407-T2 554 SIRVTWEVPDTGPVSRY-VILYKD-TSSNERELQDNTKKQTRVLRDLKtYTKYTITVYAEDKDGMRGAPAVTE 624 58999999998655555.556544.344455556666777778899962689****************99765 PP == domain 2 score: 2.1 bits; conditional E-value: 0.4 Ig_J 5 lgvkiPpvehLtvevlaesdqyqvrakWdtp...rvvkgvsFelkltveeddsdrlvsrattsdteyrlseLplGk.ytltvrakneeG 89 + + +P v + + +++s a+W+ p rv vsF + ++ + ++ +sr + +++s+L +G y + + a ++G FUN_000407-T2 627 TNGGVPRVTPRNFSLKPDSSGTALIATWTVPdptRVNGKVSFYIIKYRK-QINEQTTSRIGADKSAFTISNLMTGViYEAKIAAGSNSG 714 455678888888889999999999999*987443556679998754444.4456788888889999******99954777777665555 PP == domain 3 score: -2.0 bits; conditional E-value: 7.4 Ig_J 70 lseL.plGkytltvrakneeG 89 +s+L p +y+ v akn++G FUN_000407-T2 926 FSDLePDTEYQFNVFAKNKHG 946 556624467888888888877 PP >> Sp38 Zona-pellucida-binding protein (Sp38) N-terminal Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 3 2.2e+03 32 79 .. 59 113 .. 56 121 .. 0.63 2 ? 0.7 0.0 0.99 7.2e+02 43 79 .. 169 205 .. 154 217 .. 0.73 3 ? 9.5 0.0 0.0018 1.3 30 82 .. 257 309 .. 245 321 .. 0.82 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 3 Sp38 32 ylWiGPdgkllsgnssinitetGelvlkd.f....eeslsGvytctls...ykivk 79 +W+ +gk+++ +s+ i + G+l +++ f +++ G+y c s yki++ FUN_000407-T2 59 ITWK-RNGKQVTLDSRRTIKPDGSLYFTEiFhnrtHKPDEGIYQCEGSqsyYKIIS 113 5665.478999999999999999998876231111234468888864322255554 PP == domain 2 score: 0.7 bits; conditional E-value: 0.99 Sp38 43 sgnssinitetGelvlkdfeeslsGvytctlsykivk 79 + ++ + + G l +++++ + G y c+ + i + FUN_000407-T2 169 TTGDRFTLIPNGALQINNLRFEEQGKYECFATNEIAR 205 44456778899*********9********98766544 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0018 Sp38 30 PvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctlsykivkaea 82 P+ +W +++ g++ i + G+l++k s +G+ytc s + + +a FUN_000407-T2 257 PSITWLKDGFEISPGQNGYSILGQGNLMIKSVAVSHAGTYTCRASQTTRSFDA 309 666777777778889999999*********************98876655555 PP >> InlK_D3 Internalin K domain (D3/D4) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.83 6.1e+02 45 74 .. 502 531 .. 492 532 .. 0.87 2 ? 11.7 0.1 0.0004 0.29 45 68 .. 597 620 .. 579 624 .. 0.88 3 ? -2.1 0.0 8.1 5.9e+03 46 71 .. 929 954 .. 925 956 .. 0.81 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.83 InlK_D3 45 dlntpGdYtVtLnAededgnkaepveVtVt 74 dl+ +Y+ + A++++g+ a + eVtV+ FUN_000407-T2 502 DLEPDTEYQFYVFAKNKHGTGAISEEVTVR 531 56667799999****************995 PP == domain 2 score: 11.7 bits; conditional E-value: 0.0004 InlK_D3 45 dlntpGdYtVtLnAededgnkaep 68 dl+t +Yt+t++Aed+dg+ +p FUN_000407-T2 597 DLKTYTKYTITVYAEDKDGMRGAP 620 899*****************9988 PP == domain 3 score: -2.1 bits; conditional E-value: 8.1 InlK_D3 46 lntpGdYtVtLnAededgnkaepveV 71 l+ +Y+ ++ A++++g+ a + eV FUN_000407-T2 929 LEPDTEYQFNVFAKNKHGTGAISEEV 954 556678999999*****999987776 PP >> Ig_ILCR1 ILCR1 Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.33 2.4e+02 69 89 .. 498 518 .. 483 525 .. 0.87 2 ? 2.1 0.0 0.37 2.7e+02 50 89 .. 576 613 .. 546 621 .. 0.66 3 ? -0.4 0.0 2.2 1.6e+03 65 89 .. 791 815 .. 787 820 .. 0.83 4 ? 4.0 0.0 0.095 70 69 89 .. 924 944 .. 910 951 .. 0.85 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.33 Ig_ILCR1 69 vtFkdlepgekykikVkpiet 89 +F+dlep+++y+ V ++++ FUN_000407-T2 498 KQFSDLEPDTEYQFYVFAKNK 518 58**************99987 PP == domain 2 score: 2.1 bits; conditional E-value: 0.37 Ig_ILCR1 50 skivseeelienktksigevtFkdlepgekykikVkpiet 89 +++ +e+el + +++++ + +dl++ +ky+i+V + ++ FUN_000407-T2 576 DTSSNEREL-Q-DNTKKQTRVLRDLKTYTKYTITVYAEDK 613 333344443.3.34445556689************99987 PP == domain 3 score: -0.4 bits; conditional E-value: 2.2 Ig_ILCR1 65 sigevtFkdlepgekykikVkpiet 89 + ++ k+l p+++y++k+ ++++ FUN_000407-T2 791 DHNHYLIKNLRPNQMYYLKLVANNS 815 56778889***********999887 PP == domain 4 score: 4.0 bits; conditional E-value: 0.095 Ig_ILCR1 69 vtFkdlepgekykikVkpiet 89 tF+dlep+++y+ +V ++++ FUN_000407-T2 924 RTFSDLEPDTEYQFNVFAKNK 944 69**************99987 PP >> SNCAIP_SNCA_bd Synphilin-1 alpha-Synuclein-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 0.00011 0.083 11 28 .. 670 687 .. 667 693 .. 0.88 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.00011 SNCAIP_SNCA_bd 11 VVKLTKQLnEQTaeRIal 28 ++K KQ+nEQT+ RI FUN_000407-T2 670 IIKYRKQINEQTTSRIGA 687 68999***********75 PP >> Cadherin Cadherin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.83 6e+02 40 92 .. 166 218 .. 147 219 .. 0.69 2 ? 3.0 0.0 0.27 1.9e+02 60 89 .. 502 531 .. 495 532 .. 0.89 3 ? 4.2 0.1 0.11 82 59 86 .. 598 623 .. 548 628 .. 0.72 4 ? 0.1 0.0 2.1 1.5e+03 60 85 .. 928 953 .. 918 957 .. 0.81 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.83 Cadherin 40 e....ggnFridpetgdisttkpLDrEergeYeLtveatdssgspplsstatvtitV 92 + g+ F++ p +g ++++ +L Ee+g+Ye + at++ + + +st+ +++V FUN_000407-T2 166 VsittGDRFTLIP-NGALQIN-NLRFEEQGKYE--CFATNEIARKTHTSTTVGNVKV 218 4445566778777.7888887.9*********8..6778884455556666556665 PP == domain 2 score: 3.0 bits; conditional E-value: 0.27 Cadherin 60 DrEergeYeLtveatdssgspplsstatvt 89 D E eY+++v a+++ g+ + s+++tv+ FUN_000407-T2 502 DLEPDTEYQFYVFAKNKHGTGAISEEVTVR 531 678899***********9999999999985 PP == domain 3 score: 4.2 bits; conditional E-value: 0.11 Cadherin 59 LDrEergeYeLtveatdssgspplssta 86 L ++ +Y++tv+a+d++g ++ +++ FUN_000407-T2 598 L--KTYTKYTITVYAEDKDGMRGAPAVT 623 3..3489***********7666555444 PP == domain 4 score: 0.1 bits; conditional E-value: 2.1 Cadherin 60 DrEergeYeLtveatdssgspplsst 85 D E eY+++v a+++ g+ + s++ FUN_000407-T2 928 DLEPDTEYQFNVFAKNKHGTGAISEE 953 668889***********776666655 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.74 5.4e+02 43 92 .. 154 199 .. 138 217 .. 0.66 2 ? 8.2 0.0 0.0039 2.9 68 93 .. 276 301 .. 236 313 .. 0.83 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.74 Ig_6 43 ksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 k +V W +q ++ i+ + aL+++ ++ ++ G Y C FUN_000407-T2 154 KAKVGWRKQGSN----VSITTGDRFTLIPNGALQINNLRFEEQGKYECFA 199 556666544333....2333444345567889999999999*****9975 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0039 Ig_6 68 iileknaLrfkpvkvndsGlYiCrpr 93 il + +L +k+v v+++G+Y Cr FUN_000407-T2 276 SILGQGNLMIKSVAVSHAGTYTCRAS 301 5677899****************953 PP >> DUF1410 Protein of unknown function (DUF1410) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.39 2.8e+02 30 48 .. 492 511 .. 488 518 .. 0.84 2 ? -0.1 0.8 2.4 1.7e+03 28 49 .. 587 607 .. 574 607 .. 0.90 3 ? 2.9 0.2 0.29 2.1e+02 28 54 .. 789 814 .. 783 816 .. 0.80 4 ? 4.2 0.0 0.11 77 28 52 .. 916 941 .. 914 945 .. 0.75 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.39 DUF1410 30 ngkviff.lsnLkpnnkYkl 48 g +++ +s+L+p++ Y++ FUN_000407-T2 492 SGDTLVKqFSDLEPDTEYQF 511 57788889**********96 PP == domain 2 score: -0.1 bits; conditional E-value: 2.4 DUF1410 28 dnngkvifflsnLkpnnkYklk 49 ++++++ + l +Lk+ +kY+++ FUN_000407-T2 587 NTKKQTRV-LRDLKTYTKYTIT 607 78999999.9*********996 PP == domain 3 score: 2.9 bits; conditional E-value: 0.29 DUF1410 28 dnngkvifflsnLkpnnkYklkkivln 54 +++++ + ++nL pn+ Y+lk + +n FUN_000407-T2 789 SKDHNHYL-IKNLRPNQMYYLKLVANN 814 56666566.9***********977666 PP == domain 4 score: 4.2 bits; conditional E-value: 0.11 DUF1410 28 dnngkviff.lsnLkpnnkYklkkiv 52 + g +++ +s+L+p++ Y+++ + FUN_000407-T2 916 NVSGDTLVRtFSDLEPDTEYQFNVFA 941 5566666667***********98665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (991 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 670 (0.0262282); expected 510.9 (0.02) Passed bias filter: 565 (0.0221178); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 35 [number of targets reported over threshold] # CPU time: 0.47u 0.34s 00:00:00.81 Elapsed: 00:00:00.54 # Mc/sec: 7442.12 // Query: FUN_000407-T3 [L=632] Description: FUN_000407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-59 197.4 0.5 4.1e-14 52.9 0.0 5.0 5 I-set Immunoglobulin I-set domain 4e-59 197.5 4.0 1.2e-15 58.2 0.0 5.2 5 Ig_3 Immunoglobulin domain 3.7e-41 139.7 3.1 1.5e-11 44.8 0.0 4.5 4 Ig_2 Immunoglobulin domain 6.4e-30 103.8 10.3 4.9e-07 30.4 0.1 5.2 5 ig Immunoglobulin domain 1.9e-28 99.0 2.3 3.7e-13 50.0 0.1 2.9 2 fn3 Fibronectin type III domain 7.4e-19 68.1 0.1 0.00055 20.4 0.0 4.7 4 C2-set_2 CD80-like C2-set immunoglobulin domain 3.8e-16 59.7 12.3 0.004 17.8 0.2 8.6 6 V-set Immunoglobulin V-set domain 3.2e-10 40.7 0.0 3.5e-06 27.7 0.0 3.8 3 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 6.4e-10 39.4 0.1 1.7 9.2 0.0 4.4 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 6.8e-09 36.5 0.3 0.00036 21.3 0.0 2.7 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 8.1e-09 36.4 0.3 0.12 13.4 0.0 5.4 5 Ig_4 T-cell surface glycoprotein CD3 delta ch 1.2e-08 35.5 0.5 0.25 11.8 0.0 3.9 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor 1.2e-07 32.4 0.3 0.83 10.5 0.0 4.9 4 C1-set Immunoglobulin C1-set domain 3.1e-06 28.2 2.6 0.067 14.3 0.0 3.6 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal doma 0.00024 21.8 0.0 2.2 9.0 0.0 4.2 4 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.00078 19.7 0.3 0.74 10.1 0.0 3.8 4 V-set_CD47 CD47 immunoglobulin-like domain 0.0011 19.0 0.2 0.002 18.2 0.2 1.4 1 DUF4998 Domain of unknown function 0.0029 18.6 0.0 25 5.9 0.0 4.2 4 Shr-like_HID Heme-binding protein Shr-like, Hb-intera 0.004 17.6 0.1 0.74 10.3 0.0 3.6 3 Sp38 Zona-pellucida-binding protein (Sp38) N- 0.0042 17.8 0.1 0.26 12.0 0.1 2.6 2 Interfer-bind Interferon-alpha/beta receptor, fibronec 0.0056 17.2 0.1 0.82 10.2 0.0 2.5 2 NDNF Neuron-derived neurotrophic factor, firs 0.0088 16.6 0.4 0.28 11.8 0.1 2.7 2 InlK_D3 Internalin K domain (D3/D4) ------ inclusion threshold ------ 0.038 15.2 1.2 9.4 7.5 0.1 3.4 3 Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain 0.039 14.3 0.0 1.6 9.0 0.0 2.8 2 Ig_6 Immunoglobulin domain 0.048 14.5 0.5 83 4.2 0.1 3.7 3 Cadherin Cadherin domain 0.071 13.5 0.1 0.2 12.1 0.1 1.7 1 Monellin Monellin 0.13 12.6 0.3 39 4.7 0.0 3.8 4 fn3_4 Fibronectin-III type domain Domain annotation for each model (and alignments): >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.4 0.0 2e-14 1.9e-11 1 88 [. 28 118 .. 28 120 .. 0.86 2 ! 42.5 0.0 7.8e-14 7.4e-11 2 85 .. 126 209 .. 125 213 .. 0.85 3 ! 52.9 0.0 4.4e-17 4.1e-14 2 90 .] 229 315 .. 228 315 .. 0.94 4 ! 51.7 0.0 1e-16 9.6e-14 1 90 [] 319 403 .. 319 403 .. 0.92 5 ? -1.9 0.0 5.2 4.9e+03 12 40 .. 537 565 .. 526 584 .. 0.71 Alignments for each domain: == domain 1 score: 44.4 bits; conditional E-value: 2e-14 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee..gtatLtIsnvkkeDeGkYtckatns.ageaeasaeL 88 p+f ++++d+ v++ + a+l+c+v G+p p+++W+++g++++ ++r +k ++ ++++ ++ k DeG+Y+c+ + s ++ + +a++ FUN_000407-T3 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTLDSRRTIKPDGslYFTEIFHNRTHKPDEGIYQCEGSQSyYKIISRTARV 118 89***************************************************555556666889999*******9888744444555555 PP == domain 2 score: 42.5 bits; conditional E-value: 7.8e-14 I-set 2 kftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselke..skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 k++ +k ++v+ G++a+l c+v+ + p+ +v W k+gs+++ ++r+ + ++ L I+n++ e++GkY+c atn++ +++++ FUN_000407-T3 126 KVDVVPKTLSVTFGDTARLFCNVKHSnPKAKVGWRKQGSNVSIttGDRFTLIPNG---ALQINNLRFEEQGKYECFATNEIARKTHT 209 567789*****************9655**********776655338888888888...9*********************8777665 PP == domain 3 score: 52.9 bits; conditional E-value: 4.4e-17 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +f+ ++kd+ +++++++ lec +sG p+p+++Wlkdg e+++ ++ +++ ++ L+I++v + +G+Ytc+a+ + + a+a+L V FUN_000407-T3 229 SFQARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPgQNGYSILGQG---NLMIKSVAVSHAGTYTCRASQTTRSFDATAKLDV 315 6999**************************************66678888888...***************************9999987 PP == domain 4 score: 51.7 bits; conditional E-value: 1e-16 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p ft+k++dv + ++++++ec+++G p+p++sW+ +g+el+ ++ ++ L+++++ +D+G Y+c a+ +g+++as +L V FUN_000407-T3 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSL--SYTRVVDG---VLEVRDLVFSDKGVYQCFAKGHSGKVQASGQLFV 403 78****************************************5..34444444...9***************************999876 PP == domain 5 score: -1.9 bits; conditional E-value: 5.2 I-set 12 vkeGesaeleckvsGepepevsWlkdgse 40 + G+ +l +++ e ++v+W ++ FUN_000407-T3 537 AVPGKPRDLVAEAVTESSIRVTWEVPDTG 565 55677778888888899999999988654 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.1 3e-14 2.9e-11 2 76 .. 28 104 .. 28 105 .. 0.78 2 ! 40.4 0.0 4.7e-13 4.4e-10 6 78 .] 129 201 .. 126 201 .. 0.84 3 ! 58.2 0.0 1.3e-18 1.2e-15 5 77 .. 231 301 .. 225 301 .. 0.90 4 ! 50.6 0.0 3e-16 2.9e-13 2 77 .. 319 389 .. 318 389 .. 0.94 5 ? 0.2 0.1 1.6 1.5e+03 11 51 .. 535 576 .. 527 607 .. 0.66 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 3e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskrsssssnstLtisnvtredsGtYtCvA 76 P + +ps+t v++ +++tL+C++ gnp p+itW++ngk+ l+s +t k s + +++ +++++ d+G Y+C+ FUN_000407-T3 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQvtLDSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEG 104 778889*********************************764333333322555555555555699*********85 PP == domain 2 score: 40.4 bits; conditional E-value: 4.7e-13 Ig_3 6 vspsstvveegesvtLtCea.egnppptitWykngke..lssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 v p++ +v+ g++++L C++ ++np+ ++ W+k+g++ +++ + n+ L+i+n+++e +G+Y+C A+N FUN_000407-T3 129 VVPKTLSVTFGDTARLFCNVkHSNPKAKVGWRKQGSNvsITT-----GdrFTLIPNGALQINNLRFEEQGKYECFATN 201 5577777999**********7777777*********653333.....23379*************************9 PP == domain 3 score: 58.2 bits; conditional E-value: 1.3e-18 Ig_3 5 tvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 ++ p++t+++ ++v+L+C a+g+p+p+itW+k+g e+s+g+ +s ++++L i++v +++GtYtC+As FUN_000407-T3 231 QARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNG--YSILGQGNLMIKSVAVSHAGTYTCRAS 301 47789999****************************98886666..79***********************97 PP == domain 4 score: 50.6 bits; conditional E-value: 3e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 Pv+t +ps++++ +++v+++C+aeg p+p+i+W+ ng+ + s s ++ ++L+++++ ++d G Y+C A+ FUN_000407-T3 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGR---ELSLS--YTRVVDGVLEVRDLVFSDKGVYQCFAK 389 9**************************************...66666..57899*******************995 PP == domain 5 score: 0.2 bits; conditional E-value: 1.6 Ig_3 11 tvveegesvtLtCeaegnppptitWykngkelssgstskr...s 51 +++++g++ L ea +++ ++tW +++ ++s++ FUN_000407-T3 535 SSAVPGKPRDLVAEAVTESSIRVTWEVPDT--GPVSRYVIlykD 576 445788888888888777777999999888..343333335332 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 0.1 1.8e-14 1.7e-11 5 79 .] 33 120 .. 29 120 .. 0.88 2 ! 23.9 0.1 5.3e-08 5e-05 11 74 .. 136 210 .. 126 218 .. 0.75 3 ! 44.8 0.0 1.6e-14 1.5e-11 5 67 .. 233 304 .. 229 315 .. 0.88 4 ! 23.6 0.0 7e-08 6.6e-05 6 71 .. 325 395 .. 318 403 .. 0.77 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 1.8e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn............fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++s+t v+++++ tL+C++ gnp +++tw ++gk + +s++ +f+++ + d G+Y+C+ +++ ++ s++ ++tv FUN_000407-T3 33 EPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTlDSRRtikpdgslyfteIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3666899**************************99888555557777889777777799**************************998 PP == domain 2 score: 23.9 bits; conditional E-value: 5.3e-08 Ig_2 11 vtegesvtLtCsas.gnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnp 74 vt g++ +L C ++ +np+ak+ w+k+g+ +s ++ + + ++n e +G Y C a+n+ k+ + FUN_000407-T3 136 VTFGDTARLFCNVKhSNPKAKVGWRKQGSNVSiTTGDrftlipngaLQINNLRFEEQGKYECFATNEIARKTHTS 210 7889*********999************9999844444544444434468899************9666554444 PP == domain 3 score: 44.8 bits; conditional E-value: 1.6e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn.........fftsnvsaedsGtYtCtarntk 67 ++ +t t+ ++v L C asg p++++tw kdg ++s++qn + +++v ++++GtYtC+a++t FUN_000407-T3 233 RPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNgysilgqgnLMIKSVAVSHAGTYTCRASQTT 304 4555778999*******************************999999988889***************9864 PP == domain 4 score: 23.6 bits; conditional E-value: 7e-08 Ig_2 6 asptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn.....fftsnvsaedsGtYtCtarntkggkv 71 +s+ + +++ v++ C+a g p+++++w +g++ls s+++ + ++ +d+G+Y+C a+ ++ gkv FUN_000407-T3 325 PSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSlSYTRvvdgvLEVRDLVFSDKGVYQCFAKGHS-GKV 395 44477899****************************88888555533356688*********998644.554 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.1 5.2e-10 4.9e-07 3 71 .. 37 105 .. 35 108 .. 0.86 2 ! 28.6 0.1 2e-09 1.9e-06 2 74 .. 133 203 .. 132 209 .. 0.90 3 ! 25.1 0.1 2.5e-08 2.4e-05 8 73 .. 242 303 .. 237 310 .. 0.91 4 ! 22.6 0.0 1.5e-07 0.00014 5 79 .. 330 397 .. 326 398 .. 0.92 5 ? -1.9 0.0 6.5 6.2e+03 20 38 .. 551 569 .. 545 593 .. 0.63 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 5.2e-10 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk.vkedngrttqssllisnvteedaGtYtCvvn 71 ++v++++ atL C + g+p p++tW+++gk+ ++ ++ + + +g+ + +++ +++ + d+G Y C+++ FUN_000407-T3 37 TYVRKSKPATLKCQVG-GNPLPSITWKRNGKQVTLDSRrTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGS 105 789999**********.*********************64444455555589999999*********997 PP == domain 2 score: 28.6 bits; conditional E-value: 2e-09 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 t+ v G++a+L C++++++p + v W+k+g+ ++ + ++ + + l+i+n ++e G Y C ++n+ FUN_000407-T3 133 TLSVTFGDTARLFCNVKHSNPKAKVGWRKQGSNVSITTG--DRFTLIPNGALQINNLRFEEQGKYECFATNEI 203 67899*************************998777766..778888888*******************9975 PP == domain 3 score: 25.1 bits; conditional E-value: 2.5e-08 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++++L C as g p p++tW k+g ++ ++ ++ +q +l i +v ++aGtYtC+++ + FUN_000407-T3 242 ESTVVLECVAS-GYPKPSITWLKDGFEISPGQN---GYSILGQGNLMIKSVAVSHAGTYTCRASQT 303 689********.*************99999988...88888999******************9865 PP == domain 4 score: 22.6 bits; conditional E-value: 1.5e-07 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 +++ +++++ C a+ g p p+++Ws +g ++ +s + r+ + l +++ ++d G Y C + ++g++++ FUN_000407-T3 330 AYRNSRVRFECQAE-GIPKPNISWSLNGRELSLSYT------RVVDGVLEVRDLVFSDKGVYQCFAKGHSGKVQA 397 678899********.***************999955......*************************99999887 PP == domain 5 score: -1.9 bits; conditional E-value: 6.5 ig 20 gspgpdvtWskegktkies 38 ++ + vtW++ ++ + + FUN_000407-T3 551 TESSIRVTWEVPDTGPVSR 569 5677788888888776655 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.0 0.1 3.9e-16 3.7e-13 2 83 .. 443 530 .. 442 531 .. 0.87 2 ! 47.7 0.5 2e-15 1.9e-12 2 75 .. 541 617 .. 540 626 .. 0.87 Alignments for each domain: == domain 1 score: 50.0 bits; conditional E-value: 3.9e-16 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+n+ ++ ++t+++++W+pp ++g+i +Y y ++++ v+g++ ++++L+p+teY+++V a n++G g se+++v FUN_000407-T3 443 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVKAGGsnvdtvIVSGDTlV--KQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTV 530 7******99999***********99*************88886665555555332..568**************************9987 PP == domain 2 score: 47.7 bits; conditional E-value: 2e-15 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne...tvpgsr.etsvtltgLkpgteYevrVqavngaGeg 75 +P++l +++vt++s++v+W+ pd gp+++Y + y+++++ ++++ + +++ l++Lk +t+Y+++V+a +aG FUN_000407-T3 541 KPRDLVAEAVTESSIRVTWEVPD-TGPVSRYVILYKDTSSnerELQDYTkKQTRVLRDLKTYTKYTITVYAEDKAGLR 617 7*********************5.9************7666798877777667889***************9999754 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 5.4e-06 0.0051 15 72 .. 43 97 .. 30 105 .. 0.75 2 ! 8.7 0.0 0.0027 2.5 14 45 .. 139 169 .. 127 194 .. 0.77 3 ! 20.4 0.0 5.9e-07 0.00055 5 41 .. 234 268 .. 231 307 .. 0.81 4 ! 15.6 0.0 1.9e-05 0.018 10 44 .. 328 362 .. 319 370 .. 0.77 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 5.4e-06 C2-set_2 15 kevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredn 72 k +++C gg+P p+itW ++gk++ + ++++++p+ l+ + + ++ ++++ d FUN_000407-T3 43 KPATLKC-QVGGNPLPSITWKRNGKQV-TLDSRRTIKPDGSLYFT-EIFHNRTHKPDE 97 5678899.679***************9.77777777777777766.788888777665 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0027 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaae 45 + + + C ++ ++P++++ W ++g ++ ++ FUN_000407-T3 139 GDTARLFCNVKHSNPKAKVGWRKQGSNV-SIT 169 4567778******************998.333 PP == domain 3 score: 20.4 bits; conditional E-value: 5.9e-07 C2-set_2 5 psaslleaeekevvatCvsaggkPapritWlldgkel 41 p++++ ++e +vv++C +a+g+P+p+itWl+dg e+ FUN_000407-T3 234 PKDTMATTE-STVVLEC-VASGYPKPSITWLKDGFEI 268 455555565.99*****.899************9776 PP == domain 4 score: 15.6 bits; conditional E-value: 1.9e-05 C2-set_2 10 leae.ekevvatCvsaggkPapritWlldgkeleaa 44 + a + +v ++C a+g P+p+i+W l+g+el+ + FUN_000407-T3 328 VHAYrNSRVRFEC-QAEGIPKPNISWSLNGRELSLS 362 4444678999***.999***************9443 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.3 0.0032 3 59 108 .. 71 120 .. 32 121 .. 0.64 2 ! 15.7 0.1 2e-05 0.019 3 99 .. 131 209 .. 129 219 .. 0.72 3 ! 17.8 0.2 4.3e-06 0.004 59 108 .. 272 315 .. 232 316 .. 0.78 4 ? 0.1 0.0 1.3 1.2e+03 2 36 .. 324 355 .. 323 363 .. 0.85 5 ! 9.6 0.0 0.0015 1.4 69 104 .. 365 399 .. 355 404 .. 0.73 6 ? 0.5 0.0 1 9.4e+02 25 57 .. 551 583 .. 505 607 .. 0.79 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0032 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + r +++ d s +++ + + D+G+Y+C+ +++ +++ r+tV FUN_000407-T3 71 DSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3333333334555555666678889********65555555999999988 PP == domain 2 score: 15.7 bits; conditional E-value: 2e-05 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekk.kgrfslrkdpsrsdfsltiqnltlsDsGtYtCav...ip 94 p++++v G +++L C ++ s ++ +v W +q ++ ++++ ++rf+l ++ l+i+nl+ + +G Y+C + i+ FUN_000407-T3 131 PKTLSVTFGDTARLFCNVKHS--NPKAKVGWRKQGSN---------------VSITtGDRFTLIP-----NGALQINNLRFEEQGKYECFAtneIA 204 778888888888888877755..78888888887754...............3444499******.....*******************9533333 PP V-set 95 kgevv 99 ++++ FUN_000407-T3 205 RKTHT 209 33333 PP == domain 3 score: 17.8 bits; conditional E-value: 4.3e-06 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 ++ +s+ + + l i+++ +s++GtYtC+ ++ + +f ++ +L V FUN_000407-T3 272 QNGYSILG-----QGNLMIKSVAVSHAGTYTCR-ASQTTRSFDATAKLDV 315 55666666.....99******************.8999999999998877 PP == domain 4 score: 0.1 bits; conditional E-value: 1.3 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrq 36 +p+ v++ ++ +v++ C+ + ++W+ FUN_000407-T3 324 KPSDVHAYRNSRVRFECQAEGI---PKPNISWSLN 355 68999************98887...9999999865 PP == domain 5 score: 9.6 bits; conditional E-value: 0.0015 V-set 69 srsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 + d+ l++++l sD G+Y+C + + +++ +++ FUN_000407-T3 365 RVVDGVLEVRDLVFSDKGVYQCFA-KGHSGKVQASG 399 566999****************94.44444444444 PP == domain 6 score: 0.5 bits; conditional E-value: 1 V-set 25 seasqsvyWyrqppgkepteliayysnkseeek 57 +e s +v+W ++g ++++i+y ++s+e FUN_000407-T3 551 TESSIRVTWEVPDTGPVSRYVILYKDTSSNERE 583 456788999999999777777777777555433 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 3.7e-09 3.5e-06 4 47 .. 25 70 .. 22 88 .. 0.83 2 ? 0.2 0.0 1.3 1.3e+03 9 30 .. 230 251 .. 224 255 .. 0.90 3 ! 7.2 0.0 0.0093 8.8 7 31 .. 319 343 .. 314 368 .. 0.86 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 3.7e-09 Unc5_NetrinR_N 4 eelPifleePedayivknkpvtLkCka..akalqiyFkCngewvee 47 ++lP+f+eeP+d+y+ k+kp+tLkC++ + i +k ng++v+ FUN_000407-T3 25 ADLPHFIEEPSDTYVRKSKPATLKCQVggNPLPSITWKRNGKQVTL 70 579**********************983346678888888888765 PP == domain 2 score: 0.2 bits; conditional E-value: 1.3 Unc5_NetrinR_N 9 fleePedayivknkpvtLkCka 30 f P+d+ + v+L+C a FUN_000407-T3 230 FQARPKDTMATTESTVVLECVA 251 8899****************88 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0093 Unc5_NetrinR_N 7 PifleePedayivknkpvtLkCkaa 31 P+f ++P+d++ +n v ++C+a+ FUN_000407-T3 319 PVFTKKPSDVHAYRNSRVRFECQAE 343 9**********************96 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0029 2.7 15 57 .. 43 83 .. 36 102 .. 0.74 2 ! 8.1 0.0 0.0037 3.5 15 82 .. 140 204 .. 133 209 .. 0.79 3 ! 7.8 0.0 0.0048 4.5 13 37 .. 241 264 .. 235 304 .. 0.71 4 ! 9.2 0.0 0.0018 1.7 9 42 .. 328 359 .. 324 385 .. 0.80 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0029 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglf 57 + +l+C++ G++P P++ W+ + +++ + ++++d+ l+ FUN_000407-T3 43 KPATLKCQV-GGNPLPSITWKRNGKQVTLDSRRTIKPDG-SLY 83 566899996.779*******9987776666666666664.344 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0037 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpll 82 + rl C+++ +P+ +v Wr++ ++ ++ ++ +g ++++ r + +++++C+ +n++ FUN_000407-T3 140 DTARLFCNVKHSNPKAKVGWRKQGSNVSITTGDRFTLIPNGALQINNL---RFEEQGKYECFATNEIA 204 56799****************987777667777778888888888764...44667888888888776 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0048 C2-set_3 13 edggirlvCrsaGWyPePqvqWrde 37 + + l+C ++G yP+P++ W + FUN_000407-T3 241 TESTVVLECVASG-YPKPSITWLKD 264 567899***9998.********754 PP == domain 4 score: 9.2 bits; conditional E-value: 0.0018 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekgekl 42 v+ y++ +r +C+++G P+P+++W + g++l FUN_000407-T3 328 VHAYRNSRVRFECQAEG-IPKPNISWSLN-GREL 359 678999*********99.7*******754.4444 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 0.00022 0.21 46 85 .. 497 536 .. 466 540 .. 0.70 2 ! 21.3 0.0 3.8e-07 0.00036 19 84 .. 566 630 .. 554 632 .] 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00022 FN3_DSCAM-DSCAML_C 46 klviedLkpatwYelkvtAhneaGsteaeyefaTltltGa 85 ++dL+p t Y++ v A+n+ G+ + e++ t++ + FUN_000407-T3 497 VKQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTVRTYSSS 536 44579*****************999877666666666555 PP == domain 2 score: 21.3 bits; conditional E-value: 3.8e-07 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTltltG 84 p++ +v+ y+ ++++e l + ++++ v++dLk t+Y+++v A+ +aG a +t+ G FUN_000407-T3 566 PVSRYVILYKDTSSNERELQDY-TKKQTRVLRDLKTYTKYTITVYAEDKAGLRGAPAVTEATTNGG 630 899********99999887655.5666789*********************988876665555554 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 9.7 9.2e+03 33 47 .. 26 40 .. 21 48 .. 0.81 2 ? 7.1 0.2 0.012 11 5 51 .. 46 106 .. 42 118 .. 0.65 3 ? 2.9 0.0 0.24 2.3e+02 31 52 .. 181 202 .. 139 213 .. 0.63 4 ! 13.4 0.0 0.00013 0.12 2 54 .. 243 305 .. 242 317 .. 0.77 5 ? 5.7 0.0 0.034 32 4 62 .. 336 405 .. 333 406 .. 0.69 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 9.7 Ig_4 33 dlgksiedprglYqC 47 dl ++ie+p+ +Y+ FUN_000407-T3 26 DLPHFIEEPSDTYVR 40 8999********975 PP == domain 2 score: 7.1 bits; conditional E-value: 0.012 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek...........tldlgksiedprglYqCkeee 51 +L+C+ +itw+++gk+ + +++ ++ +++ + ++g+YqC++++ FUN_000407-T3 46 TLKCQVGGnplPSITWKRNGKQVTLDSRRtikpdgslyftEIFHNRTHKPDEGIYQCEGSQ 106 67885443124579999999999888877566666444422333344457899****9743 PP == domain 3 score: 2.9 bits; conditional E-value: 0.24 Ig_4 31 tldlgksiedprglYqCkeeek 52 l++++ +++g Y+C +++ FUN_000407-T3 181 ALQINNLRFEEQGKYECFATNE 202 778888888********94333 PP == domain 4 score: 13.4 bits; conditional E-value: 0.00013 Ig_4 2 dkVlLtCnsss...keitwlkdgkeikeskek.......tldlgksiedprglYqCkeeekkk 54 +V+L+C s +itwlkdg ei+ ++ +l ++++ g+Y+C+ +++++ FUN_000407-T3 243 STVVLECVASGypkPSITWLKDGFEISPGQNGysilgqgNLMIKSVAVSHAGTYTCRASQTTR 305 68*****444333368**********9998877788878889999999********9644443 PP == domain 5 score: 5.7 bits; conditional E-value: 0.034 Ig_4 4 VlLtCnsss...keitwlkdgkeikeskek....tldlgksiedprglYqCk....eeekkkssslqvyy 62 V +C+ + +i w +g e + s ++ l++ + + ++g+YqC + + ++s +l vyy FUN_000407-T3 336 VRFECQAEGipkPNISWSLNGRELSLSYTRvvdgVLEVRDLVFSDKGVYQCFakghSGKVQASGQLFVYY 405 555665443322578899999999888888777778888888899******9776533555666677776 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.0 0.005 4.7 11 33 .. 40 62 .. 30 136 .. 0.75 2 ! 11.8 0.0 0.00026 0.25 12 33 .. 241 262 .. 232 267 .. 0.80 3 ! 11.4 0.0 0.00034 0.33 9 33 .. 329 353 .. 322 357 .. 0.79 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.005 Ig_PDGFR_d4 11 assgeqtvtCvaeGmPqPeveWf 33 +s+ t++C G P P+++W FUN_000407-T3 40 RKSKPATLKCQVGGNPLPSITWK 62 56777899**************6 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00026 Ig_PDGFR_d4 12 ssgeqtvtCvaeGmPqPeveWf 33 +++ ++ Cva G+P+P+++W+ FUN_000407-T3 241 TESTVVLECVASGYPKPSITWL 262 44555678*************7 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00034 Ig_PDGFR_d4 9 shassgeqtvtCvaeGmPqPeveWf 33 + +++ C aeG+P+P+++W FUN_000407-T3 329 HAYRNSRVRFECQAEGIPKPNISWS 353 34456677789*************7 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00087 0.83 12 61 .. 41 86 .. 30 106 .. 0.66 2 ? 5.7 0.0 0.029 27 4 43 .. 130 168 .. 127 202 .. 0.75 3 ! 9.5 0.0 0.0018 1.7 5 46 .. 234 273 .. 230 304 .. 0.72 4 ? -0.4 0.0 2.2 2.1e+03 13 43 .. 333 361 .. 320 368 .. 0.66 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00087 C1-set 12 kgkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqll 61 k+k++tL C v g p ++tW++ng++vt ++ +k ++s y++ FUN_000407-T3 41 KSKPATLKCQVGGN--PLPSITWKRNGKQVTL--DSRRTIKPDGSLYFTE 86 3899*******984..344789*********6..6666666666666654 PP == domain 2 score: 5.7 bits; conditional E-value: 0.029 C1-set 4 lppspeelkgkkntLvClvtgfyPpdikVtWlkngqevte 43 +p++ + + g+++ L C v+ P + kV W k+g++v+ FUN_000407-T3 130 VPKTLSVTFGDTARLFCNVKHSNP-KAKVGWRKQGSNVSI 168 555555555999*******98777.89********99985 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0018 C1-set 5 ppspeelkgkkntLvClvtgfyPpdikVtWlkngqevtegvk 46 p+++ +++++++L C+++g+ p ++tWlk+g e++ g + FUN_000407-T3 234 PKDTMATTESTVVLECVASGYPKP--SITWLKDGFEISPGQN 273 5555666799**********9666..679*****99998644 PP == domain 4 score: -0.4 bits; conditional E-value: 2.2 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevte 43 ++ + C ++g+ p +++W ng+e++ FUN_000407-T3 333 NSRVRFECQAEGIPKP--NISWSLNGRELSL 361 5556666777776444..678999*999875 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 7.1e-05 0.067 1 93 [] 444 532 .. 444 532 .. 0.72 2 ! 11.4 0.7 0.00057 0.54 10 82 .. 549 612 .. 542 627 .. 0.68 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 7.1e-05 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevys 90 Pe+v +++ + +t++ ++W +p + +++++y + + + t+ sg + ++++Lep+t+Y++ v ++n+ + se+ + FUN_000407-T3 444 PENVVAQVLS-DTEIELTWSPPGIPRGKILEYVCIYVKAGGSNVDTV-------IVSGDTLVKQFSDLEPDTEYQFYVFAKNKhgtgAISEEVT 529 6777777777.888888888887667777777776644333222222.......24677888899*************9998778888888888 PP Pur_ac_phosph_N 91 ftT 93 ++T FUN_000407-T3 530 VRT 532 887 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00057 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +++s++v+W p++ +pv +y ++++ss + + + yt + +l++L+ t+Y +v +e+ FUN_000407-T3 549 AvTESSIRVTWEVPDT--GPVSRYVILYKDTSS-NERELQDYT-------KKQTRVLRDLKTYTKYTITVYAED 612 55789*********97..677777777654433.334444443.......345667899999999988887775 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.28 2.7e+02 20 42 .. 40 62 .. 32 83 .. 0.84 2 ? -2.1 0.0 6.1 5.7e+03 104 119 .. 192 207 .. 187 211 .. 0.86 3 ? 4.6 0.0 0.053 50 26 45 .. 246 265 .. 231 288 .. 0.85 4 ! 9.0 0.0 0.0023 2.2 20 47 .. 332 358 .. 312 372 .. 0.79 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.28 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwf 42 r + l c g p+p itw FUN_000407-T3 40 RKSKPATLKCQVGGNPLPSITWK 62 555566799*************6 PP == domain 2 score: -2.1 bits; conditional E-value: 6.1 Ig_VEGFR-1-like_5th 104 sgvysctarnelgnrt 119 g y c a ne+ +t FUN_000407-T3 192 QGKYECFATNEIARKT 207 589********99887 PP == domain 3 score: 4.6 bits; conditional E-value: 0.053 Ig_VEGFR-1-like_5th 26 kltctafgipmpnitwfwqp 45 l c a g p p itw+ + FUN_000407-T3 246 VLECVASGYPKPSITWLKDG 265 589*************9765 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0023 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwfwqpcd 47 r + r ++ c a gip pni+w + + FUN_000407-T3 332 R-NSRVRFECQAEGIPKPNISWSLNGRE 358 3.568999**************876655 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 2.2 2.1e+03 49 88 .. 59 106 .. 46 120 .. 0.60 2 ? 4.3 0.1 0.048 46 28 93 .. 140 206 .. 116 217 .. 0.74 3 ! 10.1 0.0 0.00078 0.74 27 101 .. 242 315 .. 227 326 .. 0.67 4 ? -0.5 0.0 1.6 1.5e+03 27 61 .. 333 362 .. 320 401 .. 0.67 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2.2 V-set_CD47 49 vkWkfnnkdifisnktekkst..........LkldfsdalsGnYtCevte 88 + Wk+n+k+++ + + ++ +G Y Ce ++ FUN_000407-T3 59 ITWKRNGKQVTLDSRRTI--KpdgslyfteiFHNRTHKPDEGIYQCEGSQ 106 788888888776544422..233554544422222233346777777655 PP == domain 2 score: 4.3 bits; conditional E-value: 0.048 V-set_CD47 28 dtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst....Lkldfsd.alsGnYtCevtelsnev 93 dt + C+v++ + ++ v W+ +++++ i + + + + L++++ + +G Y C +t++ + FUN_000407-T3 140 DTARLFCNVKH----SNPKAKVGWRKQGSNVSITTGDRFTLIpngaLQINNLRfEEQGKYECFATNEIARK 206 66778899966....446788******999999988855555888866665441458*****999876543 PP == domain 3 score: 10.1 bits; conditional E-value: 0.00078 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst.....Lkld.fsdalsGnYtCevtelsnevkttieLkl 101 +tvv+eC + ++ + W ++ +i ++ s+ L ++ + +G+YtC +++++++ t +L + FUN_000407-T3 242 ESTVVLECVASGYPKP-----SITWLKDGFEISPGQNGY--SIlgqgnLMIKsVAVSHAGTYTCRASQTTRSFDATAKLDV 315 5777777777664444.....457777777766544432..222355544441455679***************9999987 PP == domain 4 score: -0.5 bits; conditional E-value: 1.6 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifis 61 n+ v eC+ + +++ n ++W++n++++ s FUN_000407-T3 333 NSRVRFECQAEGIPKPN-----ISWSLNGRELSLS 362 67777778776666555.....5999999887655 PP >> DUF4998 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.2 2.1e-06 0.002 82 189 .. 505 609 .. 456 614 .. 0.88 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 2.1e-06 DUF4998 82 eEgsytfeivtydkkgnsSvavevsaevYGdsYqssLtnrslksaelekkeltikwskvekeaklvkteleYtnkagetktvrikkkeeqtkltdf 177 + y+f +++++k+g ++ ev+ +Y +s + r l++ +++++++ ++w+ + + + + Y++++ ++++++ + k+++ +l d FUN_000407-T3 505 PDTEYQFYVFAKNKHGTGAISEEVTVRTYSSSAVPG-KPRDLVAEAVTESSIRVTWEVPDTGP-VSRYVILYKDTSSNERELQDYTKKQTRVLRDL 598 5678*************************8875554.89*******************99999.99****************************** PP DUF4998 178 kpgtsfkyrtvy 189 k t++++ tvy FUN_000407-T3 599 KTYTKYTI-TVY 609 *9999987.445 PP >> Shr-like_HID Heme-binding protein Shr-like, Hb-interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.027 25 23 64 .. 158 196 .. 136 197 .. 0.87 2 ? 5.3 0.0 0.04 38 34 64 .. 264 297 .. 236 301 .. 0.84 3 ? 1.1 0.0 0.86 8.1e+02 32 63 .. 353 384 .. 347 386 .. 0.86 4 ? -1.6 0.0 5.9 5.6e+03 59 70 .. 600 611 .. 585 628 .. 0.82 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.027 Shr-like_HID 23 aWrsaitevkvnGtelssdkYti.eagkitldagvftkageyt 64 Wr++ ++v++ t+ +d++t+ +g +++++ f+++g+y+ FUN_000407-T3 158 GWRKQGSNVSI--TT--GDRFTLiPNGALQINNLRFEEQGKYE 196 69999999999..44..777**9988**************996 PP == domain 2 score: 5.3 bits; conditional E-value: 0.04 Shr-like_HID 34 nGtelssdk..Yti.eagkitldagvftkageyt 64 +G e+s+++ Y+i +g++ +++ + ++ag+yt FUN_000407-T3 264 DGFEISPGQngYSIlGQGNLMIKSVAVSHAGTYT 297 67777755556****88****************8 PP == domain 3 score: 1.1 bits; conditional E-value: 0.86 Shr-like_HID 32 kvnGtelssdkYti.eagkitldagvftkagey 63 ++nG els + Yt +g +++ + vf+ +g y FUN_000407-T3 353 SLNGRELSLS-YTRvVDGVLEVRDLVFSDKGVY 384 579***9999.887789**********999988 PP == domain 4 score: -1.6 bits; conditional E-value: 5.9 Shr-like_HID 59 kageytitikAt 70 + +ytit+ A+ FUN_000407-T3 600 TYTKYTITVYAE 611 455788888876 PP >> Sp38 Zona-pellucida-binding protein (Sp38) N-terminal Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.3 1.3e+03 32 79 .. 59 113 .. 56 121 .. 0.64 2 ? 1.6 0.0 0.41 3.9e+02 43 79 .. 169 205 .. 153 218 .. 0.73 3 ! 10.3 0.0 0.00078 0.74 30 82 .. 257 309 .. 245 321 .. 0.82 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.3 Sp38 32 ylWiGPdgkllsgnssinitetGelvlkd.f....eeslsGvytctls...ykivk 79 +W+ +gk+++ +s+ i + G+l +++ f +++ G+y c s yki++ FUN_000407-T3 59 ITWK-RNGKQVTLDSRRTIKPDGSLYFTEiFhnrtHKPDEGIYQCEGSqsyYKIIS 113 5665.478999999999999999998876231111234468888864322255554 PP == domain 2 score: 1.6 bits; conditional E-value: 0.41 Sp38 43 sgnssinitetGelvlkdfeeslsGvytctlsykivk 79 + ++ + + G l +++++ + G y c+ + i + FUN_000407-T3 169 TTGDRFTLIPNGALQINNLRFEEQGKYECFATNEIAR 205 44456778899*********9********98766544 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00078 Sp38 30 PvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctlsykivkaea 82 P+ +W +++ g++ i + G+l++k s +G+ytc s + + +a FUN_000407-T3 257 PSITWLKDGFEISPGQNGYSILGQGNLMIKSVAVSHAGTYTCRASQTTRSFDA 309 666777777778889999999*********************98876655555 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.21 1.9e+02 42 85 .. 472 516 .. 453 531 .. 0.80 2 ! 12.0 0.1 0.00028 0.26 43 87 .. 569 612 .. 551 623 .. 0.80 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.21 Interfer-bind 42 lqYkvsywknssnkekkelestnelv.vlsdLepnteYCvsVqae 85 l+Y +y k + ++ ++++ s +lv +sdLep teY + V a+ FUN_000407-T3 472 LEYVCIYVKAGGSNVDTVIVSGDTLVkQFSDLEPDTEYQFYVFAK 516 67888888888776777776666655169*********9888773 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00028 Interfer-bind 43 qYkvsywknssn.kekkelestnelvvlsdLepnteYCvsVqaesr 87 Y + y +ssn +e + +++++++ vl+dL+ t+Y ++V+ae + FUN_000407-T3 569 RYVILYKDTSSNeRELQDYTKKQTR-VLRDLKTYTKYTITVYAE-D 612 699********94444555555555.****************93.3 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.0 0.00087 0.82 83 113 .. 490 520 .. 425 533 .. 0.85 2 ? 4.4 0.0 0.054 51 82 111 .. 584 613 .. 541 627 .. 0.75 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00087 NDNF 83 vCvgkktvqtvseLkpdtqYyfdvFavdqkr 113 + g++ v +s+L+pdt+Y f vFa +++ FUN_000407-T3 490 IVSGDTLVKQFSDLEPDTEYQFYVFAKNKHG 520 44577778889***************99875 PP == domain 2 score: 4.4 bits; conditional E-value: 0.054 NDNF 82 ivCvgkktvqtvseLkpdtqYyfdvFavdq 111 + kk+ ++++Lk t+Y ++v+a d+ FUN_000407-T3 584 LQDYTKKQTRVLRDLKTYTKYTITVYAEDK 613 555567888899**************9876 PP >> InlK_D3 Internalin K domain (D3/D4) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.38 3.6e+02 45 74 .. 502 531 .. 492 532 .. 0.87 2 ! 11.8 0.1 0.0003 0.28 45 68 .. 597 620 .. 577 624 .. 0.87 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.38 InlK_D3 45 dlntpGdYtVtLnAededgnkaepveVtVt 74 dl+ +Y+ + A++++g+ a + eVtV+ FUN_000407-T3 502 DLEPDTEYQFYVFAKNKHGTGAISEEVTVR 531 56667799999****************995 PP == domain 2 score: 11.8 bits; conditional E-value: 0.0003 InlK_D3 45 dlntpGdYtVtLnAededgnkaep 68 dl+t +Yt+t++Aed++g+ +p FUN_000407-T3 597 DLKTYTKYTITVYAEDKAGLRGAP 620 89*****************99988 PP >> Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.1 0.076 72 11 85 .. 454 523 .. 441 530 .. 0.68 2 ? 7.5 0.1 0.0099 9.4 42 89 .. 542 588 .. 525 592 .. 0.72 3 ? 7.3 0.1 0.012 11 46 89 .. 546 588 .. 539 615 .. 0.66 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.076 Kre9_KNH 11 gspvtitWsdsptdp......gtvtlvLvngssnnlksvktiasgisnssgsytwtvpsdleagegYqlqivsesekntgi 85 +++++tW sp + v +++ +g s +v+t++ + sg + ++ sdle++++Yq+ + ++++++tg+ FUN_000407-T3 454 DTEIELTW--SPPGIprgkilEYVCIYVKAGGS----NVDTVI--V---SGDTLVKQFSDLEPDTEYQFYVFAKNKHGTGA 523 35588888..33333367777777777777755....333333..2...6777788889**********999999877765 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0099 Kre9_KNH 42 svktiasgisnssgsytwtvpsdleagegYqlqivsesekntgiynyS 89 + + +a++++ ss +tw vp + + ++ Y + +++s ++ + y+ FUN_000407-T3 542 PRDLVAEAVTESSIRVTWEVPDTGPVSR-YVILYKDTSSNERELQDYT 588 4455678999999999999855555554.9999999887666666676 PP == domain 3 score: 7.3 bits; conditional E-value: 0.012 Kre9_KNH 46 iasgisnssgsytwtvpsdleagegYqlqivsesekntgiynyS 89 +a++++ ss +tw vp + + ++ Y + +++s ++ + y+ FUN_000407-T3 546 VAEAVTESSIRVTWEVPDTGPVSR-YVILYKDTSSNERELQDYT 588 566666677777777644444443.7777776665555445555 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.32 3e+02 43 92 .. 154 199 .. 137 217 .. 0.66 2 ? 9.0 0.0 0.0017 1.6 68 93 .. 276 301 .. 235 313 .. 0.82 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.32 Ig_6 43 ksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 k +V W +q ++ i+ + aL+++ ++ ++ G Y C FUN_000407-T3 154 KAKVGWRKQGSN----VSITTGDRFTLIPNGALQINNLRFEEQGKYECFA 199 556666554433....2334444345567889999999999*****9975 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0017 Ig_6 68 iileknaLrfkpvkvndsGlYiCrpr 93 il + +L +k+v v+++G+Y Cr FUN_000407-T3 276 SILGQGNLMIKSVAVSHAGTYTCRAS 301 5678899****************953 PP >> Cadherin Cadherin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.35 3.3e+02 40 92 .. 166 218 .. 146 219 .. 0.69 2 ? 3.7 0.0 0.12 1.1e+02 60 89 .. 502 531 .. 495 532 .. 0.89 3 ? 4.2 0.1 0.088 83 62 86 .. 599 623 .. 549 628 .. 0.79 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.35 Cadherin 40 e....ggnFridpetgdisttkpLDrEergeYeLtveatdssgspplsstatvtitV 92 + g+ F++ p +g ++++ +L Ee+g+Ye + at++ + + +st+ +++V FUN_000407-T3 166 VsittGDRFTLIP-NGALQIN-NLRFEEQGKYE--CFATNEIARKTHTSTTVGNVKV 218 4445567788888.7888887.9*********8..6788884455566666556665 PP == domain 2 score: 3.7 bits; conditional E-value: 0.12 Cadherin 60 DrEergeYeLtveatdssgspplsstatvt 89 D E eY+++v a+++ g+ + s+++tv+ FUN_000407-T3 502 DLEPDTEYQFYVFAKNKHGTGAISEEVTVR 531 678899***********9999999999985 PP == domain 3 score: 4.2 bits; conditional E-value: 0.088 Cadherin 62 EergeYeLtveatdssgspplssta 86 ++ +Y++tv+a+d++g ++ +++ FUN_000407-T3 599 KTYTKYTITVYAEDKAGLRGAPAVT 623 3479***********6555544444 PP >> Monellin Monellin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.00021 0.2 7 32 .. 508 533 .. 506 535 .. 0.93 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00021 Monellin 7 diqlyvYasdkLfkadvdEdyKirqr 32 ++q yv+a +k + +++E+ +r + FUN_000407-T3 508 EYQFYVFAKNKHGTGAISEEVTVRTY 533 9*******************999987 PP >> fn3_4 Fibronectin-III type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 9.1 8.7e+03 37 64 .. 194 218 .. 185 231 .. 0.67 2 ? 2.8 0.0 0.16 1.5e+02 2 24 .. 440 462 .. 439 476 .. 0.93 3 ? -0.6 0.0 1.9 1.8e+03 72 93 .. 499 520 .. 495 529 .. 0.82 4 ? 4.7 0.0 0.041 39 2 52 .. 538 588 .. 537 619 .. 0.78 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 9.1 fn3_4 37 sYelflyqeetktssstdsWkkigdvkA 64 Ye f+++e +++ + + +g+vk FUN_000407-T3 194 KYECFATNEIARKTHT-S--TTVGNVKV 218 6889999884444433.2..35555555 PP == domain 2 score: 2.8 bits; conditional E-value: 0.16 fn3_4 2 pPqkpelkiakvevptgivlsWn 24 P+kpe +a+v ++t+i l+W FUN_000407-T3 440 FPEKPENVVAQVLSDTEIELTWS 462 69********************6 PP == domain 3 score: -0.6 bits; conditional E-value: 1.9 fn3_4 72 tlsqfkegkkyyfavrakDiyg 93 ++s++++++ y+f v ak +g FUN_000407-T3 499 QFSDLEPDTEYQFYVFAKNKHG 520 5789999999****99999987 PP == domain 4 score: 4.7 bits; conditional E-value: 0.041 fn3_4 2 pPqkpelkiakvevptgivlsWnvekldpkaaevesYelflyqeetktsss 52 +P kp+ +a+ ++++i ++W+v+++ p+ v Y+ ++e++ + + FUN_000407-T3 538 VPGKPRDLVAEAVTESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDYT 588 68899989999999***********99999988888876666665555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (632 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 775 (0.0303386); expected 510.9 (0.02) Passed bias filter: 670 (0.0262282); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 27 [number of targets reported over threshold] # CPU time: 0.38u 0.34s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 6173.94 // Query: FUN_000407-T4 [L=633] Description: FUN_000407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-60 201.6 1.0 6.6e-15 55.4 0.0 5.0 5 I-set Immunoglobulin I-set domain 2.8e-59 198.0 6.5 6.7e-16 59.0 0.1 5.5 5 Ig_3 Immunoglobulin domain 9.8e-42 141.6 4.8 1.9e-12 47.7 0.1 4.4 4 Ig_2 Immunoglobulin domain 6.8e-32 110.1 11.8 4.9e-07 30.4 0.1 5.2 5 ig Immunoglobulin domain 1.3e-29 102.7 1.7 2.1e-13 50.7 0.4 2.9 2 fn3 Fibronectin type III domain 1.1e-18 67.5 0.2 0.00058 20.3 0.0 4.9 4 C2-set_2 CD80-like C2-set immunoglobulin domain 1.2e-16 61.4 12.5 0.0071 17.0 0.0 8.1 7 V-set Immunoglobulin V-set domain 8.2e-11 42.2 0.2 0.17 12.3 0.0 4.4 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 2.1e-10 41.3 0.0 3.5e-06 27.7 0.0 3.8 3 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 4.6e-09 37.0 0.5 0.00056 20.7 0.1 2.7 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 1.4e-08 35.6 0.5 0.12 13.4 0.0 5.6 4 Ig_4 T-cell surface glycoprotein CD3 delta ch 2.4e-08 34.5 0.7 0.27 11.7 0.0 4.0 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor 3.5e-07 31.0 3.7 0.83 10.5 0.0 5.2 4 C1-set Immunoglobulin C1-set domain 9.5e-07 29.8 1.4 0.072 14.2 0.0 3.8 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal doma 1.1e-05 26.0 0.2 0.74 10.6 0.0 3.8 3 Ig_Rha78A_N Rha78A-like, N-terminal immunoglobulin d 8.1e-05 23.5 0.0 22 6.1 0.0 4.4 4 Shr-like_HID Heme-binding protein Shr-like, Hb-intera 0.00032 21.4 0.1 2.6 8.7 0.0 4.2 4 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.00049 20.2 0.2 0.00089 19.3 0.2 1.4 1 DUF4998 Domain of unknown function 0.0006 20.2 0.1 0.72 10.3 0.0 4.2 4 Sp38 Zona-pellucida-binding protein (Sp38) N- 0.00063 20.5 0.0 0.081 13.7 0.1 2.6 2 Interfer-bind Interferon-alpha/beta receptor, fibronec 0.00064 20.0 0.1 0.69 10.2 0.0 3.7 4 V-set_CD47 CD47 immunoglobulin-like domain 0.0016 19.0 0.0 0.27 11.8 0.0 2.6 2 NDNF Neuron-derived neurotrophic factor, firs 0.0043 17.6 0.3 0.17 12.5 0.1 2.7 2 InlK_D3 Internalin K domain (D3/D4) ------ inclusion threshold ------ 0.014 16.6 1.4 9.9 7.5 0.0 3.5 3 Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain 0.04 14.3 0.0 1.7 9.0 0.0 2.8 2 Ig_6 Immunoglobulin domain 0.045 14.3 0.3 0.22 12.1 0.2 2.2 2 Ig_J Tip attachment protein J, Ig-like domain 0.077 13.9 0.5 45 5.0 0.1 3.5 3 Cadherin Cadherin domain 0.087 13.2 0.1 23 5.4 0.0 3.7 4 fn3_4 Fibronectin-III type domain 0.17 12.3 0.2 24 5.4 0.0 2.6 2 Y_Y_Y Y_Y_Y domain Domain annotation for each model (and alignments): >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.4 0.0 2.1e-14 1.9e-11 1 88 [. 28 118 .. 28 120 .. 0.86 2 ! 42.5 0.0 8.4e-14 7.4e-11 2 85 .. 126 209 .. 125 213 .. 0.85 3 ! 55.4 0.0 7.5e-18 6.6e-15 2 90 .] 229 315 .. 228 315 .. 0.94 4 ! 53.8 0.0 2.5e-17 2.2e-14 1 90 [] 319 404 .. 319 404 .. 0.92 5 ? -1.6 0.0 4.6 4.1e+03 10 40 .. 536 566 .. 527 586 .. 0.71 Alignments for each domain: == domain 1 score: 44.4 bits; conditional E-value: 2.1e-14 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee..gtatLtIsnvkkeDeGkYtckatns.ageaeasaeL 88 p+f ++++d+ v++ + a+l+c+v G+p p+++W+++g++++ ++r +k ++ ++++ ++ k DeG+Y+c+ + s ++ + +a++ FUN_000407-T4 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTLDSRRTIKPDGslYFTEIFHNRTHKPDEGIYQCEGSQSyYKIISRTARV 118 89***************************************************555556666889999*******9888744444555555 PP == domain 2 score: 42.5 bits; conditional E-value: 8.4e-14 I-set 2 kftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselke..skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 k++ +k ++v+ G++a+l c+v+ + p+ +v W k+gs+++ ++r+ + ++ L I+n++ e++GkY+c atn++ +++++ FUN_000407-T4 126 KVDVVPKTLSVTFGDTARLFCNVKHSnPKAKVGWRKQGSNVSIttGDRFTLIPNG---ALQINNLRFEEQGKYECFATNEIARKTHT 209 567789*****************9655**********776655338888888888...9*********************8777665 PP == domain 3 score: 55.4 bits; conditional E-value: 7.5e-18 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +f++++kd+++++++++ lec +sG p+p+++Wlkdg e+++ ++ +++ ++ L+I++v + +G+Ytc+a+ + + a+a+L V FUN_000407-T4 229 SFQTRPKDTVATTESTVVLECVASGYPKPSITWLKDGFEISPgQNGYSILGQG---NLMIKSVAVSHAGTYTCRASQTTRSFDATAKLDV 315 799***************************************66678888888...***************************9999987 PP == domain 4 score: 53.8 bits; conditional E-value: 2.5e-17 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p ft+k++dv + + +++++ec++ G p+p++sW+ +g+el++s+ +v + L+++++ +D+G Y+c a+ +g+++as +L V FUN_000407-T4 319 PVFTKKPSDVHAYKKSRVQFECQAAGIPKPNISWSLNGRELSTSSYTRVG----DGVLEVRDLVFSDKGVYQCFAKGHSGKVQASGQLFV 404 78****************************************87655554....457***************************999876 PP == domain 5 score: -1.6 bits; conditional E-value: 4.6 I-set 10 vevkeGesaeleckvsGepepevsWlkdgse 40 ++ G+ +l +++ e ++v+W ++ FUN_000407-T4 536 SSAVPGKPRDLVAEAVTESSIRVTWEVPDTG 566 5566778888888899999999***988764 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.1 3.3e-14 2.9e-11 2 76 .. 28 104 .. 28 105 .. 0.78 2 ! 40.4 0.0 5e-13 4.4e-10 6 78 .] 129 201 .. 126 201 .. 0.84 3 ! 59.0 0.1 7.6e-19 6.7e-16 5 77 .. 231 301 .. 225 301 .. 0.90 4 ! 51.8 0.0 1.4e-16 1.2e-13 2 77 .. 319 390 .. 318 390 .. 0.92 5 ? 1.1 0.1 0.92 8.1e+02 4 51 .. 529 577 .. 528 609 .. 0.67 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 3.3e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskrsssssnstLtisnvtredsGtYtCvA 76 P + +ps+t v++ +++tL+C++ gnp p+itW++ngk+ l+s +t k s + +++ +++++ d+G Y+C+ FUN_000407-T4 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQvtLDSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEG 104 778889*********************************764333333322555555555555699*********85 PP == domain 2 score: 40.4 bits; conditional E-value: 5e-13 Ig_3 6 vspsstvveegesvtLtCea.egnppptitWykngke..lssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 v p++ +v+ g++++L C++ ++np+ ++ W+k+g++ +++ + n+ L+i+n+++e +G+Y+C A+N FUN_000407-T4 129 VVPKTLSVTFGDTARLFCNVkHSNPKAKVGWRKQGSNvsITT-----GdrFTLIPNGALQINNLRFEEQGKYECFATN 201 5577777999**********7777777*********653333.....23379*************************9 PP == domain 3 score: 59.0 bits; conditional E-value: 7.6e-19 Ig_3 5 tvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 ++ p++tv++ ++v+L+C a+g+p+p+itW+k+g e+s+g+ +s ++++L i++v +++GtYtC+As FUN_000407-T4 231 QTRPKDTVATTESTVVLECVASGYPKPSITWLKDGFEISPGQNG--YSILGQGNLMIKSVAVSHAGTYTCRAS 301 47889999****************************98886666..79***********************97 PP == domain 4 score: 51.8 bits; conditional E-value: 1.4e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 Pv+t +ps++++ ++++v+++C+a+g p+p+i+W+ ng+els+ s+ ++ + ++L+++++ ++d G Y+C A+ FUN_000407-T4 319 PVFTKKPSDVHAYKKSRVQFECQAAGIPKPNISWSLNGRELST---SS-YTRVGDGVLEVRDLVFSDKGVYQCFAK 390 9**************************************6444...32.4689********************995 PP == domain 5 score: 1.1 bits; conditional E-value: 0.92 Ig_3 4 itvspsstvveegesvtLtCeaegnppptitWykngkelssgstskr...s 51 itv s+++++g++ L ea +++ ++tW +++ ++s++ FUN_000407-T4 529 ITVRTYSSSAVPGKPRDLVAEAVTESSIRVTWEVPDT--GPVSRYVIlykD 577 5655556667889999999999888888999999998..343333335442 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 0.1 1.9e-14 1.7e-11 5 79 .] 33 120 .. 29 120 .. 0.88 2 ! 23.9 0.1 5.7e-08 5e-05 11 74 .. 136 210 .. 126 218 .. 0.75 3 ! 47.7 0.1 2.1e-15 1.9e-12 3 67 .. 231 304 .. 229 315 .. 0.90 4 ! 24.2 0.0 4.6e-08 4.1e-05 6 71 .. 325 396 .. 318 404 .. 0.76 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 1.9e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn............fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++s+t v+++++ tL+C++ gnp +++tw ++gk + +s++ +f+++ + d G+Y+C+ +++ ++ s++ ++tv FUN_000407-T4 33 EPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTlDSRRtikpdgslyfteIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3666899**************************99888555557777889777777799**************************998 PP == domain 2 score: 23.9 bits; conditional E-value: 5.7e-08 Ig_2 11 vtegesvtLtCsas.gnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnp 74 vt g++ +L C ++ +np+ak+ w+k+g+ +s ++ + + ++n e +G Y C a+n+ k+ + FUN_000407-T4 136 VTFGDTARLFCNVKhSNPKAKVGWRKQGSNVSiTTGDrftlipngaLQINNLRFEEQGKYECFATNEIARKTHTS 210 7889*********999************9999844444544444434468899************9666554444 PP == domain 3 score: 47.7 bits; conditional E-value: 2.1e-15 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn.........fftsnvsaedsGtYtCtarntk 67 + ++ +tv t+ ++v L C asg p++++tw kdg ++s++qn + +++v ++++GtYtC+a++t FUN_000407-T4 231 QTRPKDTVATTESTVVLECVASGYPKPSITWLKDGFEISPGQNgysilgqgnLMIKSVAVSHAGTYTCRASQTT 304 56777799***********************************999999988889***************9864 PP == domain 4 score: 24.2 bits; conditional E-value: 4.6e-08 Ig_2 6 asptvvtegesvtLtCsasgnppakytwykdgkvls..ssqn......fftsnvsaedsGtYtCtarntkggkv 71 +s+ + +++ v++ C+a g p+++++w +g++ls s+ + ++ +d+G+Y+C a+ ++ gkv FUN_000407-T4 325 PSDVHAYKKSRVQFECQAAGIPKPNISWSLNGRELStsSY-TrvgdgvLEVRDLVFSDKGVYQCFAKGHS-GKV 396 4447889*****************************6333.24676644467899*********998544.554 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.1 5.6e-10 4.9e-07 3 71 .. 37 105 .. 35 108 .. 0.86 2 ! 28.6 0.1 2.2e-09 1.9e-06 2 74 .. 133 203 .. 132 209 .. 0.90 3 ! 25.9 0.1 1.5e-08 1.3e-05 5 73 .. 239 303 .. 235 310 .. 0.90 4 ! 29.7 0.0 9.6e-10 8.5e-07 5 79 .. 330 398 .. 326 399 .. 0.94 5 ? -1.9 0.0 7.1 6.2e+03 21 38 .. 553 570 .. 546 594 .. 0.62 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 5.6e-10 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk.vkedngrttqssllisnvteedaGtYtCvvn 71 ++v++++ atL C + g+p p++tW+++gk+ ++ ++ + + +g+ + +++ +++ + d+G Y C+++ FUN_000407-T4 37 TYVRKSKPATLKCQVG-GNPLPSITWKRNGKQVTLDSRrTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGS 105 789999**********.*********************64444455555589999999*********997 PP == domain 2 score: 28.6 bits; conditional E-value: 2.2e-09 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 t+ v G++a+L C++++++p + v W+k+g+ ++ + ++ + + l+i+n ++e G Y C ++n+ FUN_000407-T4 133 TLSVTFGDTARLFCNVKHSNPKAKVGWRKQGSNVSITTG--DRFTLIPNGALQINNLRFEEQGKYECFATNEI 203 67899*************************998777766..778888888*******************9975 PP == domain 3 score: 25.9 bits; conditional E-value: 1.5e-08 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 + +++++L C as g p p++tW k+g ++ ++ ++ +q +l i +v ++aGtYtC+++ + FUN_000407-T4 239 ATTESTVVLECVAS-GYPKPSITWLKDGFEISPGQN---GYSILGQGNLMIKSVAVSHAGTYTCRASQT 303 56689*********.*************99999988...88888999******************9865 PP == domain 4 score: 29.7 bits; conditional E-value: 9.6e-10 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 +++ +++++ C a g p p+++Ws +g ++ +s++ +r+++ l +++ ++d G Y C + ++g++++ FUN_000407-T4 330 AYKKSRVQFECQAA-GIPKPNISWSLNGRELSTSSY-----TRVGDGVLEVRDLVFSDKGVYQCFAKGHSGKVQA 398 677899********.*********************.....**************************99999887 PP == domain 5 score: -1.9 bits; conditional E-value: 7.1 ig 21 spgpdvtWskegktkies 38 ++ + vtW++ ++ + + FUN_000407-T4 553 ESSIRVTWEVPDTGPVSR 570 667778888877766554 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.1 0.0 3.8e-16 3.3e-13 2 83 .. 444 531 .. 443 532 .. 0.87 2 ! 50.7 0.4 2.4e-16 2.1e-13 2 77 .. 542 618 .. 541 625 .. 0.88 Alignments for each domain: == domain 1 score: 50.1 bits; conditional E-value: 3.8e-16 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+n+ ++ ++t+++++W+pp ++g+i +Y y ++++ v+g++ ++++L+p+teY+++V a n++G g se+++v FUN_000407-T4 444 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVKAGGsnvdtvIVSGDTlV--KQFSDLEPDTEYQFNVFAKNKHGTGAISEEITV 531 7******99999***********99*************88886665555555332..568**************************9987 PP == domain 2 score: 50.7 bits; conditional E-value: 2.4e-16 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne...tvpgsr.etsvtltgLkpgteYevrVqavngaGegee 77 +P++l +++vt++s++v+W+ pd gp+++Y + y+++++ ++++++ +++ l++Lk +t+Y+++V+a ++G ++ FUN_000407-T4 542 KPRDLVAEAVTESSIRVTWEVPD-TGPVSRYVILYKDTSSnerELQDNTkKQTRVLRDLKTYTKYTITVYAEDKDG--MR 618 7*********************5.9************76677****9998777889***************98875..44 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 5.8e-06 0.0051 15 72 .. 43 97 .. 30 105 .. 0.75 2 ! 8.7 0.0 0.0029 2.5 14 45 .. 139 169 .. 127 194 .. 0.77 3 ! 20.3 0.0 6.6e-07 0.00058 8 41 .. 236 268 .. 230 307 .. 0.81 4 ! 14.7 0.0 3.8e-05 0.034 14 47 .. 333 363 .. 321 373 .. 0.76 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 5.8e-06 C2-set_2 15 kevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredn 72 k +++C gg+P p+itW ++gk++ + ++++++p+ l+ + + ++ ++++ d FUN_000407-T4 43 KPATLKC-QVGGNPLPSITWKRNGKQV-TLDSRRTIKPDGSLYFT-EIFHNRTHKPDE 97 5678899.679***************9.77777777777777766.788888777665 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0029 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaae 45 + + + C ++ ++P++++ W ++g ++ ++ FUN_000407-T4 139 GDTARLFCNVKHSNPKAKVGWRKQGSNV-SIT 169 4567778******************998.333 PP == domain 3 score: 20.3 bits; conditional E-value: 6.6e-07 C2-set_2 8 slleaeekevvatCvsaggkPapritWlldgkel 41 ++ ++e +vv++C +a+g+P+p+itWl+dg e+ FUN_000407-T4 236 DTVATTESTVVLEC-VASGYPKPSITWLKDGFEI 268 344455699*****.899************9776 PP == domain 4 score: 14.7 bits; conditional E-value: 3.8e-05 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaaets 47 + +v ++C a g P+p+i+W l+g+el +++s FUN_000407-T4 333 KSRVQFEC-QAAGIPKPNISWSLNGREL--STSS 363 56889999.8889***************..3333 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.3 0.0034 3 59 108 .. 71 120 .. 32 121 .. 0.64 2 ! 15.7 0.1 2.1e-05 0.019 3 99 .. 131 209 .. 129 219 .. 0.72 3 ? 3.4 0.0 0.13 1.2e+02 3 36 .. 234 264 .. 232 269 .. 0.88 4 ! 17.0 0.0 8.1e-06 0.0071 63 108 .. 276 315 .. 266 316 .. 0.83 5 ? -2.1 0.0 7 6.2e+03 2 36 .. 324 355 .. 323 364 .. 0.80 6 ! 12.3 0.0 0.00023 0.2 65 104 .. 362 400 .. 353 405 .. 0.73 7 ? 1.0 0.0 0.75 6.6e+02 25 62 .. 552 589 .. 535 609 .. 0.74 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0034 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + r +++ d s +++ + + D+G+Y+C+ +++ +++ r+tV FUN_000407-T4 71 DSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3333333334555555666678889********65555555999999988 PP == domain 2 score: 15.7 bits; conditional E-value: 2.1e-05 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekk.kgrfslrkdpsrsdfsltiqnltlsDsGtYtCav...ip 94 p++++v G +++L C ++ s ++ +v W +q ++ ++++ ++rf+l ++ l+i+nl+ + +G Y+C + i+ FUN_000407-T4 131 PKTLSVTFGDTARLFCNVKHS--NPKAKVGWRKQGSN---------------VSITtGDRFTLIP-----NGALQINNLRFEEQGKYECFAtneIA 204 778888888888888877755..78888888887754...............3444499******.....*******************9533333 PP V-set 95 kgevv 99 ++++ FUN_000407-T4 205 RKTHT 209 33333 PP == domain 3 score: 3.4 bits; conditional E-value: 0.13 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrq 36 p+ + + ++ +v L C+ s + + s++W ++ FUN_000407-T4 234 PKDTVATTESTVVLECVASGY---PKPSITWLKD 264 7778889999******99999...*******985 PP == domain 4 score: 17.0 bits; conditional E-value: 8.1e-06 V-set 63 slrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 s+ + + l i+++ +s++GtYtC+ ++ + +f ++ +L V FUN_000407-T4 276 SILG-----QGNLMIKSVAVSHAGTYTCR-ASQTTRSFDATAKLDV 315 4444.....899*****************.8999999999998877 PP == domain 5 score: -2.1 bits; conditional E-value: 7 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrq 36 +p+ v++ +v++ C+ + ++W+ FUN_000407-T4 324 KPSDVHAYKKSRVQFECQAAGI---PKPNISWSLN 355 5788888999999999988887...8888998865 PP == domain 6 score: 12.3 bits; conditional E-value: 0.00023 V-set 65 rkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 + ++ +d+ l++++l sD G+Y+C + + +++ +++ FUN_000407-T4 362 SSYTRVGDGVLEVRDLVFSDKGVYQCFA-KGHSGKVQASG 400 4467899*******************94.44444444444 PP == domain 7 score: 1.0 bits; conditional E-value: 0.75 V-set 25 seasqsvyWyrqppgkepteliayysnkseeekkkgrf 62 +e s +v+W ++g ++++i+y ++s+e ++ FUN_000407-T4 552 TESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDNT 589 4578899****999988888888888855554444443 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0031 2.7 15 57 .. 43 83 .. 36 102 .. 0.74 2 ! 8.1 0.0 0.004 3.5 15 82 .. 140 204 .. 133 209 .. 0.79 3 ! 7.6 0.0 0.006 5.3 13 37 .. 241 264 .. 236 304 .. 0.71 4 ! 12.3 0.0 0.0002 0.17 9 61 .. 328 376 .. 324 390 .. 0.79 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0031 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglf 57 + +l+C++ G++P P++ W+ + +++ + ++++d+ l+ FUN_000407-T4 43 KPATLKCQV-GGNPLPSITWKRNGKQVTLDSRRTIKPDG-SLY 83 566899996.779*******9987776666666666664.344 PP == domain 2 score: 8.1 bits; conditional E-value: 0.004 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpll 82 + rl C+++ +P+ +v Wr++ ++ ++ ++ +g ++++ r + +++++C+ +n++ FUN_000407-T4 140 DTARLFCNVKHSNPKAKVGWRKQGSNVSITTGDRFTLIPNGALQINNL---RFEEQGKYECFATNEIA 204 56799****************987777667777778888888888764...44667888888888776 PP == domain 3 score: 7.6 bits; conditional E-value: 0.006 C2-set_3 13 edggirlvCrsaGWyPePqvqWrde 37 + + l+C ++G yP+P++ W + FUN_000407-T4 241 TESTVVLECVASG-YPKPSITWLKD 264 567899***9998.********754 PP == domain 4 score: 12.3 bits; conditional E-value: 0.0002 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevet 61 v+ y++ ++ +C++aG P+P+++W +g++l+++s ++ +dg+ ev+ FUN_000407-T4 328 VHAYKKSRVQFECQAAG-IPKPNISWS-LNGRELSTSSY--TRVGDGVLEVRD 376 67899***********9.7*******7.57888888776..444557777765 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 4e-09 3.5e-06 4 47 .. 25 70 .. 22 88 .. 0.83 2 ? 0.1 0.0 1.6 1.4e+03 8 30 .. 229 251 .. 224 255 .. 0.90 3 ! 7.8 0.0 0.0062 5.4 7 42 .. 319 356 .. 314 369 .. 0.77 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 4e-09 Unc5_NetrinR_N 4 eelPifleePedayivknkpvtLkCka..akalqiyFkCngewvee 47 ++lP+f+eeP+d+y+ k+kp+tLkC++ + i +k ng++v+ FUN_000407-T4 25 ADLPHFIEEPSDTYVRKSKPATLKCQVggNPLPSITWKRNGKQVTL 70 579**********************983346678888888888765 PP == domain 2 score: 0.1 bits; conditional E-value: 1.6 Unc5_NetrinR_N 8 ifleePedayivknkpvtLkCka 30 f + P+d+ + v+L+C a FUN_000407-T4 229 SFQTRPKDTVATTESTVVLECVA 251 58899****************88 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0062 Unc5_NetrinR_N 7 PifleePedayivknkpvtLkCkaa..kalqiyFkCng 42 P+f ++P+d++ k+ v+++C+aa + +i + ng FUN_000407-T4 319 PVFTKKPSDVHAYKKSRVQFECQAAgiPKPNISWSLNG 356 9**********************972234455555555 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 9.5e-05 0.083 46 84 .. 498 536 .. 467 541 .. 0.69 2 ! 20.7 0.1 6.4e-07 0.00056 19 85 .. 567 632 .. 555 633 .] 0.84 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 9.5e-05 FN3_DSCAM-DSCAML_C 46 klviedLkpatwYelkvtAhneaGsteaeyefaTltltG 84 ++dL+p t Y+++v A+n+ G+ + e++ t++ FUN_000407-T4 498 VKQFSDLEPDTEYQFNVFAKNKHGTGAISEEITVRTYSS 536 44579*****************99887666666655555 PP == domain 2 score: 20.7 bits; conditional E-value: 6.4e-07 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTltltGa 85 p++ +v+ y+ ++++e l +n+ ++++ v++dLk t+Y+++v A+ + G+ a +t+ G+ FUN_000407-T4 567 PVSRYVILYKDTSSNERELQDNT-KKQTRVLRDLKTYTKYTITVYAEDKDGMRGAPAVTEATTNGGE 632 899*********99998887665.5666799********************9999888877777776 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.2 0.013 12 5 51 .. 46 106 .. 42 118 .. 0.65 2 ? 2.9 0.0 0.26 2.3e+02 31 52 .. 181 202 .. 139 213 .. 0.63 3 ! 13.4 0.0 0.00014 0.12 2 54 .. 243 305 .. 242 317 .. 0.77 4 ? 4.7 0.0 0.07 62 14 62 .. 349 406 .. 333 407 .. 0.64 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.013 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek...........tldlgksiedprglYqCkeee 51 +L+C+ +itw+++gk+ + +++ ++ +++ + ++g+YqC++++ FUN_000407-T4 46 TLKCQVGGnplPSITWKRNGKQVTLDSRRtikpdgslyftEIFHNRTHKPDEGIYQCEGSQ 106 67885443124579999999999888877566666444422333344457899****9743 PP == domain 2 score: 2.9 bits; conditional E-value: 0.26 Ig_4 31 tldlgksiedprglYqCkeeek 52 l++++ +++g Y+C +++ FUN_000407-T4 181 ALQINNLRFEEQGKYECFATNE 202 778888888********94333 PP == domain 3 score: 13.4 bits; conditional E-value: 0.00014 Ig_4 2 dkVlLtCnsss...keitwlkdgkeikeskek.......tldlgksiedprglYqCkeeekkk 54 +V+L+C s +itwlkdg ei+ ++ +l ++++ g+Y+C+ +++++ FUN_000407-T4 243 STVVLECVASGypkPSITWLKDGFEISPGQNGysilgqgNLMIKSVAVSHAGTYTCRASQTTR 305 68*****444333368**********9998877788878889999999********9644443 PP == domain 4 score: 4.7 bits; conditional E-value: 0.07 Ig_4 14 eitwlkdgkeikeskek.....tldlgksiedprglYqCk....eeekkkssslqvyy 62 +i w +g e ++s+ + l++ + + ++g+YqC + + ++s +l vyy FUN_000407-T4 349 NISWSLNGRELSTSSYTrvgdgVLEVRDLVFSDKGVYQCFakghSGKVQASGQLFVYY 406 6777777777666665545555667777777899*****9776533555666677776 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.0 0.0054 4.7 11 33 .. 40 62 .. 30 136 .. 0.75 2 ! 11.7 0.0 0.00031 0.27 12 33 .. 241 262 .. 232 267 .. 0.80 3 ! 10.6 0.0 0.00065 0.57 8 33 .. 327 353 .. 322 363 .. 0.81 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0054 Ig_PDGFR_d4 11 assgeqtvtCvaeGmPqPeveWf 33 +s+ t++C G P P+++W FUN_000407-T4 40 RKSKPATLKCQVGGNPLPSITWK 62 56777899**************6 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00031 Ig_PDGFR_d4 12 ssgeqtvtCvaeGmPqPeveWf 33 +++ ++ Cva G+P+P+++W+ FUN_000407-T4 241 TESTVVLECVASGYPKPSITWL 262 44555678*************7 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00065 Ig_PDGFR_d4 8 d.shassgeqtvtCvaeGmPqPeveWf 33 d + ++++ + C a G+P+P+++W FUN_000407-T4 327 DvHAYKKSRVQFECQAAGIPKPNISWS 353 6334456677889*************7 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00094 0.83 12 61 .. 41 86 .. 30 106 .. 0.66 2 ? 5.7 0.0 0.031 27 4 43 .. 130 168 .. 127 202 .. 0.75 3 ! 10.1 0.0 0.0013 1.1 5 46 .. 234 273 .. 230 304 .. 0.73 4 ? 1.0 0.0 0.9 7.9e+02 13 44 .. 333 362 .. 320 369 .. 0.66 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00094 C1-set 12 kgkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqll 61 k+k++tL C v g p ++tW++ng++vt ++ +k ++s y++ FUN_000407-T4 41 KSKPATLKCQVGGN--PLPSITWKRNGKQVTL--DSRRTIKPDGSLYFTE 86 3899*******984..344789*********6..6666666666666654 PP == domain 2 score: 5.7 bits; conditional E-value: 0.031 C1-set 4 lppspeelkgkkntLvClvtgfyPpdikVtWlkngqevte 43 +p++ + + g+++ L C v+ P + kV W k+g++v+ FUN_000407-T4 130 VPKTLSVTFGDTARLFCNVKHSNP-KAKVGWRKQGSNVSI 168 555555555999*******98777.89********99985 PP == domain 3 score: 10.1 bits; conditional E-value: 0.0013 C1-set 5 ppspeelkgkkntLvClvtgfyPpdikVtWlkngqevtegvk 46 p+++ +++++++L C+++g+ p ++tWlk+g e++ g + FUN_000407-T4 234 PKDTVATTESTVVLECVASGYPKP--SITWLKDGFEISPGQN 273 677778889***********9666..679*****99998644 PP == domain 4 score: 1.0 bits; conditional E-value: 0.9 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevteg 44 ++ + C + g+ p +++W ng+e++++ FUN_000407-T4 333 KSRVQFECQAAGIPKP--NISWSLNGRELSTS 362 5555666666666444..689999****9985 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 8.1e-05 0.072 1 93 [] 445 533 .. 445 533 .. 0.71 2 ! 11.6 0.6 0.00053 0.46 10 82 .. 550 613 .. 543 628 .. 0.63 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 8.1e-05 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevys 90 Pe+v +++ + +t++ ++W +p + +++++y + + + t+ sg + ++++Lep+t+Y++ v ++n+ + se+ + FUN_000407-T4 445 PENVVAQVLS-DTEIELTWSPPGIPRGKILEYVCIYVKAGGSNVDTV-------IVSGDTLVKQFSDLEPDTEYQFNVFAKNKhgtgAISEEIT 530 6777777777.888888888887667777777776644333222222.......24677888899*************9998778888888888 PP Pur_ac_phosph_N 91 ftT 93 ++T FUN_000407-T4 531 VRT 533 777 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00053 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +++s++v+W p++ +pv +y ++++ss+ e ++++ + +l++L+ t+Y +v +e+ FUN_000407-T4 550 AvTESSIRVTWEVPDT--GPVSRYVILYKDTSSNER--------ELQDNTKKQTRVLRDLKTYTKYTITVYAED 613 55789*********86..455555555544333221........112344555667888888888888887664 PP >> Ig_Rha78A_N Rha78A-like, N-terminal immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 0.00084 0.74 17 75 .. 345 415 .. 335 420 .. 0.72 2 ? 5.9 0.0 0.023 21 17 101 .. 455 533 .. 447 535 .. 0.78 3 ? 4.5 0.2 0.067 59 15 89 .. 551 617 .. 548 629 .. 0.70 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00084 Ig_Rha78A_N 17 earPrlsWklesdergvrqtayqievass..............eeadvw.....dsgkvessesvlvpypgkpLksrt 75 ++P++sW l++ r+ + ++y +v ++ + +sgkv+ s ++ v y+g+pL +t FUN_000407-T4 345 IPKPNISWSLNG--RELSTSSYT-RVGDGvlevrdlvfsdkgvY----QcfakgHSGKVQASGQLFVYYEGEPLPVTT 415 589********9..455555554.55555555555577644430....256666********************8766 PP == domain 2 score: 5.9 bits; conditional E-value: 0.023 Ig_Rha78A_N 17 earPrlsWklesdergvrqtayqievasseeadvwdsgkvessesvlvpypgkpLksrtryywrVrvwdedgeasawsepasfet 101 +++ +l+W ++ +rg+ + + i v+ ++ + d+ v+ + lv ++ +L+++t+y++ V + +++g+ a se +++t FUN_000407-T4 455 DTEIELTWSPPGIPRGKILEYVCIYVKAGG--SNVDTVIVSGDT--LV-KQFSDLEPDTEYQFNVFAKNKHGT-GAISEEITVRT 533 567778888888888888888888888876..556666666664..55.4789******************96.88998888776 PP == domain 3 score: 4.5 bits; conditional E-value: 0.067 Ig_Rha78A_N 15 idearPrlsWklesdergvrqtayqievasseeadvwdsgkvessesvlvpypgkpLksrtryywrVrvwdedge 89 + e++ r++W++++ + y i+ +++++++++ + + ++ ++ v ++Lk t+y+++V + d+dg FUN_000407-T4 551 VTESSIRVTWEVPD---TGPVSRYVILYKDTSSNERELQDNTKK--QTRV---LRDLKTYTKYTITVYAEDKDGM 617 66788999999999...577888999999986433333333333..3333...48999**********9999994 PP >> Shr-like_HID Heme-binding protein Shr-like, Hb-interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.029 25 23 64 .. 158 196 .. 136 197 .. 0.87 2 ? 5.4 0.0 0.042 37 34 64 .. 264 297 .. 235 301 .. 0.83 3 ? 6.1 0.0 0.025 22 32 64 .. 353 386 .. 346 388 .. 0.90 4 ? -1.6 0.0 6.4 5.6e+03 61 70 .. 603 612 .. 596 631 .. 0.75 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.029 Shr-like_HID 23 aWrsaitevkvnGtelssdkYti.eagkitldagvftkageyt 64 Wr++ ++v++ t+ +d++t+ +g +++++ f+++g+y+ FUN_000407-T4 158 GWRKQGSNVSI--TT--GDRFTLiPNGALQINNLRFEEQGKYE 196 69999999999..44..777**9988**************996 PP == domain 2 score: 5.4 bits; conditional E-value: 0.042 Shr-like_HID 34 nGtelssdk..Yti.eagkitldagvftkageyt 64 +G e+s+++ Y+i +g++ +++ + ++ag+yt FUN_000407-T4 264 DGFEISPGQngYSIlGQGNLMIKSVAVSHAGTYT 297 77777755556****88****************8 PP == domain 3 score: 6.1 bits; conditional E-value: 0.025 Shr-like_HID 32 kvnGtelssdkYti.eagkitldagvftkageyt 64 ++nG els+++Yt +g +++ + vf+ +g y+ FUN_000407-T4 353 SLNGRELSTSSYTRvGDGVLEVRDLVFSDKGVYQ 386 58***********9999**********9999885 PP == domain 4 score: -1.6 bits; conditional E-value: 6.4 Shr-like_HID 61 geytitikAt 70 +ytit+ A+ FUN_000407-T4 603 TKYTITVYAE 612 5678888775 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.3 2.7e+02 20 42 .. 40 62 .. 32 83 .. 0.84 2 ? -2.1 0.0 6.5 5.7e+03 104 119 .. 192 207 .. 187 211 .. 0.86 3 ? 4.5 0.0 0.061 54 26 45 .. 246 265 .. 234 289 .. 0.85 4 ! 8.7 0.0 0.0029 2.6 22 44 .. 333 355 .. 311 366 .. 0.78 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.3 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwf 42 r + l c g p+p itw FUN_000407-T4 40 RKSKPATLKCQVGGNPLPSITWK 62 555566799*************6 PP == domain 2 score: -2.1 bits; conditional E-value: 6.5 Ig_VEGFR-1-like_5th 104 sgvysctarnelgnrt 119 g y c a ne+ +t FUN_000407-T4 192 QGKYECFATNEIARKT 207 589********99887 PP == domain 3 score: 4.5 bits; conditional E-value: 0.061 Ig_VEGFR-1-like_5th 26 kltctafgipmpnitwfwqp 45 l c a g p p itw+ + FUN_000407-T4 246 VLECVASGYPKPSITWLKDG 265 589*************9765 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0029 Ig_VEGFR-1-like_5th 22 dqrhkltctafgipmpnitwfwq 44 r ++ c a gip pni+w + FUN_000407-T4 333 KSRVQFECQAAGIPKPNISWSLN 355 3578999*************765 PP >> DUF4998 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.2 1e-06 0.00089 82 188 .. 506 609 .. 457 614 .. 0.88 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1e-06 DUF4998 82 eEgsytfeivtydkkgnsSvavevsaevYGdsYqssLtnrslksaelekkeltikwskvekeaklvkteleYtnkagetktvrikkkeeqtkltdf 177 + y+f++++++k+g ++ e++ +Y +s + r l++ +++++++ ++w+ + + + + Y++++ ++++++ + k+++ +l d FUN_000407-T4 506 PDTEYQFNVFAKNKHGTGAISEEITVRTYSSSAVPG-KPRDLVAEAVTESSIRVTWEVPDTGP-VSRYVILYKDTSSNERELQDNTKKQTRVLRDL 599 5678*************************8875554.89*******************99999.99****************************** PP DUF4998 178 kpgtsfkyrtv 188 k t++++ tv FUN_000407-T4 600 KTYTKYTI-TV 609 *9999987.44 PP >> Sp38 Zona-pellucida-binding protein (Sp38) N-terminal Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.4 1.3e+03 32 79 .. 59 113 .. 56 121 .. 0.64 2 ? 1.6 0.0 0.44 3.9e+02 43 79 .. 169 205 .. 153 218 .. 0.73 3 ! 10.3 0.0 0.00082 0.72 30 82 .. 257 309 .. 243 321 .. 0.83 4 ? 1.5 0.0 0.47 4.2e+02 29 74 .. 347 390 .. 335 405 .. 0.79 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.4 Sp38 32 ylWiGPdgkllsgnssinitetGelvlkd.f....eeslsGvytctls...ykivk 79 +W+ +gk+++ +s+ i + G+l +++ f +++ G+y c s yki++ FUN_000407-T4 59 ITWK-RNGKQVTLDSRRTIKPDGSLYFTEiFhnrtHKPDEGIYQCEGSqsyYKIIS 113 5665.478999999999999999998876231111234468888864322255554 PP == domain 2 score: 1.6 bits; conditional E-value: 0.44 Sp38 43 sgnssinitetGelvlkdfeeslsGvytctlsykivk 79 + ++ + + G l +++++ + G y c+ + i + FUN_000407-T4 169 TTGDRFTLIPNGALQINNLRFEEQGKYECFATNEIAR 205 44456778899*********9********98766544 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00082 Sp38 30 PvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctlsykivkaea 82 P+ +W +++ g++ i + G+l++k s +G+ytc s + + +a FUN_000407-T4 257 PSITWLKDGFEISPGQNGYSILGQGNLMIKSVAVSHAGTYTCRASQTTRSFDA 309 66777777777888999999**********************98876655555 PP == domain 4 score: 1.5 bits; conditional E-value: 0.47 Sp38 29 dPvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctls 74 P +W +g+ ls +s+ ++ G l ++d+ s Gvy c+ + FUN_000407-T4 347 KPNISWS-LNGRELSTSSYTRVG-DGVLEVRDLVFSDKGVYQCFAK 390 5777775.589999999999986.599999***999*******865 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.1 92 42 86 .. 473 518 .. 454 529 .. 0.81 2 ! 13.7 0.1 9.2e-05 0.081 43 88 .. 570 614 .. 552 625 .. 0.84 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.1 Interfer-bind 42 lqYkvsywknssnkekkelestnelv.vlsdLepnteYCvsVqaes 86 l+Y +y k + ++ ++++ s +lv +sdLep teY ++V a++ FUN_000407-T4 473 LEYVCIYVKAGGSNVDTVIVSGDTLVkQFSDLEPDTEYQFNVFAKN 518 67888888888776777777666655169*********99998843 PP == domain 2 score: 13.7 bits; conditional E-value: 9.2e-05 Interfer-bind 43 qYkvsywknssnkekkelestnelvvlsdLepnteYCvsVqaesrk 88 Y + y +ssn+++ + ++++++ vl+dL+ t+Y ++V+a ++k FUN_000407-T4 570 RYVILYKDTSSNERELQDNTKKQTRVLRDLKTYTKYTITVYA-EDK 614 699*********7777777777778*****************.444 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 2.4 2.1e+03 49 88 .. 59 106 .. 46 120 .. 0.60 2 ? 4.3 0.1 0.052 46 28 93 .. 140 206 .. 116 217 .. 0.74 3 ! 10.2 0.0 0.00078 0.69 27 101 .. 242 315 .. 227 326 .. 0.67 4 ? -1.0 0.0 2.4 2.1e+03 44 65 .. 345 366 .. 333 402 .. 0.61 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2.4 V-set_CD47 49 vkWkfnnkdifisnktekkst..........LkldfsdalsGnYtCevte 88 + Wk+n+k+++ + + ++ +G Y Ce ++ FUN_000407-T4 59 ITWKRNGKQVTLDSRRTI--KpdgslyfteiFHNRTHKPDEGIYQCEGSQ 106 788888888776544422..233554544422222233346777777655 PP == domain 2 score: 4.3 bits; conditional E-value: 0.052 V-set_CD47 28 dtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst....Lkldfsd.alsGnYtCevtelsnev 93 dt + C+v++ + ++ v W+ +++++ i + + + + L++++ + +G Y C +t++ + FUN_000407-T4 140 DTARLFCNVKH----SNPKAKVGWRKQGSNVSITTGDRFTLIpngaLQINNLRfEEQGKYECFATNEIARK 206 66778899966....446788******999999988855555888866665441458*****999876543 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00078 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst.....Lkld.fsdalsGnYtCevtelsnevkttieLkl 101 +tvv+eC + ++ + W ++ +i ++ s+ L ++ + +G+YtC +++++++ t +L + FUN_000407-T4 242 ESTVVLECVASGYPKP-----SITWLKDGFEISPGQNGY--SIlgqgnLMIKsVAVSHAGTYTCRASQTTRSFDATAKLDV 315 5778888877664444.....457777777776544432..222355544441455679***************9999987 PP == domain 4 score: -1.0 bits; conditional E-value: 2.4 V-set_CD47 44 isevyvkWkfnnkdifisnkte 65 i++ ++W++n++++ +s t+ FUN_000407-T4 345 IPKPNISWSLNGRELSTSSYTR 366 4555679999999988877664 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.8 0.0 0.00031 0.27 83 112 .. 491 520 .. 425 533 .. 0.86 2 ? 4.5 0.0 0.053 47 85 111 .. 588 614 .. 543 628 .. 0.75 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00031 NDNF 83 vCvgkktvqtvseLkpdtqYyfdvFavdqk 112 + g++ v +s+L+pdt+Y f+vFa +++ FUN_000407-T4 491 IVSGDTLVKQFSDLEPDTEYQFNVFAKNKH 520 44577778889***************9986 PP == domain 2 score: 4.5 bits; conditional E-value: 0.053 NDNF 85 vgkktvqtvseLkpdtqYyfdvFavdq 111 kk+ ++++Lk t+Y ++v+a d+ FUN_000407-T4 588 NTKKQTRVLRDLKTYTKYTITVYAEDK 614 556777889**************9876 PP >> InlK_D3 Internalin K domain (D3/D4) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.37 3.3e+02 45 74 .. 503 532 .. 493 533 .. 0.88 2 ! 12.5 0.1 0.00019 0.17 45 68 .. 598 621 .. 579 625 .. 0.88 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.37 InlK_D3 45 dlntpGdYtVtLnAededgnkaepveVtVt 74 dl+ +Y+ ++ A++++g+ a + e+tV+ FUN_000407-T4 503 DLEPDTEYQFNVFAKNKHGTGAISEEITVR 532 6667789*****************999995 PP == domain 2 score: 12.5 bits; conditional E-value: 0.00019 InlK_D3 45 dlntpGdYtVtLnAededgnkaep 68 dl+t +Yt+t++Aed+dg+ +p FUN_000407-T4 598 DLKTYTKYTITVYAEDKDGMRGAP 621 899*****************9988 PP >> Kre9_KNH Kre9/KNH-like N-terminal Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.011 9.9 11 85 .. 455 524 .. 442 531 .. 0.69 2 ? 5.7 0.1 0.041 36 44 82 .. 545 581 .. 528 589 .. 0.68 3 ? 5.9 0.1 0.034 30 9 41 .. 552 583 .. 542 618 .. 0.55 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.011 Kre9_KNH 11 gspvtitWsdsptdp......gtvtlvLvngssnnlksvktiasgisnssgsytwtvpsdleagegYqlqivsesekntgi 85 +++++tW sp + v +++ +g s +v+t++ + sg + ++ sdle++++Yq+++ ++++++tg+ FUN_000407-T4 455 DTEIELTW--SPPGIprgkilEYVCIYVKAGGS----NVDTVI--V---SGDTLVKQFSDLEPDTEYQFNVFAKNKHGTGA 524 35588888..33333367777777777777755....333433..2...677778889****************9877765 PP == domain 2 score: 5.7 bits; conditional E-value: 0.041 Kre9_KNH 44 ktiasgisnssgsytwtvpsdleagegYqlqivsesekn 82 + +a++++ ss +tw vp + + ++ Y + +++s +n FUN_000407-T4 545 DLVAEAVTESSIRVTWEVPDTGPVSR-YVILYKDTS-SN 581 45568888888888888855555544.888777777.34 PP == domain 3 score: 5.9 bits; conditional E-value: 0.034 Kre9_KNH 9 dagspvtitWsdsptdpgtvtlvLvngssnnlk 41 + s++ +tW+ +t p + ++L++ +s+n FUN_000407-T4 552 TE-SSIRVTWEVPDTGPVSRYVILYKDTSSNER 583 22.446666655555555555555555443333 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.34 3e+02 43 92 .. 154 199 .. 137 217 .. 0.66 2 ? 9.0 0.0 0.0019 1.7 68 93 .. 276 301 .. 236 313 .. 0.83 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.34 Ig_6 43 ksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 k +V W +q ++ i+ + aL+++ ++ ++ G Y C FUN_000407-T4 154 KAKVGWRKQGSN----VSITTGDRFTLIPNGALQINNLRFEEQGKYECFA 199 556666554433....2334444345567889999999999*****9975 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0019 Ig_6 68 iileknaLrfkpvkvndsGlYiCrpr 93 il + +L +k+v v+++G+Y Cr FUN_000407-T4 276 SILGQGNLMIKSVAVSHAGTYTCRAS 301 5677899****************953 PP >> Ig_J Tip attachment protein J, Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 3.6 3.1e+03 70 90 .. 501 522 .. 457 535 .. 0.73 2 ? 12.1 0.2 0.00025 0.22 27 97 .. 555 624 .. 532 629 .. 0.73 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 3.6 Ig_J 70 lseL.plGkytltvrakneeGq 90 +s+L p +y+ v akn++G FUN_000407-T4 501 FSDLePDTEYQFNVFAKNKHGT 522 4555245678888888888874 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00025 Ig_J 27 qvrakWdtprvvkgvsFelkltveeddsdrlvsrattsdteyrlseLp.lGkytltvrakneeGqqGeeasv 97 +r++W+ p + ++ + l ++ +s++ +++t+ ++ +l++L+ kyt+tv a +++G +G +a + FUN_000407-T4 555 SIRVTWEVPDTGPVSRY-VILYKD-TSSNERELQDNTKKQTRVLRDLKtYTKYTITVYAEDKDGMRGAPAVT 624 58999999998655555.556554.344455556666777778899962689****************9976 PP >> Cadherin Cadherin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.38 3.4e+02 40 92 .. 166 218 .. 146 219 .. 0.69 2 ? 2.6 0.0 0.3 2.7e+02 60 89 .. 503 532 .. 496 533 .. 0.87 3 ? 5.0 0.1 0.052 45 58 86 .. 598 624 .. 548 629 .. 0.70 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.38 Cadherin 40 e....ggnFridpetgdisttkpLDrEergeYeLtveatdssgspplsstatvtitV 92 + g+ F++ p +g ++++ +L Ee+g+Ye + at++ + + +st+ +++V FUN_000407-T4 166 VsittGDRFTLIP-NGALQIN-NLRFEEQGKYE--CFATNEIARKTHTSTTVGNVKV 218 4445567788888.7888887.9*********8..6788884455566666556665 PP == domain 2 score: 2.6 bits; conditional E-value: 0.3 Cadherin 60 DrEergeYeLtveatdssgspplsstatvt 89 D E eY+++v a+++ g+ + s++ tv+ FUN_000407-T4 503 DLEPDTEYQFNVFAKNKHGTGAISEEITVR 532 678899***********9999999888875 PP == domain 3 score: 5.0 bits; conditional E-value: 0.052 Cadherin 58 pLDrEergeYeLtveatdssgspplssta 86 L ++ +Y++tv+a+d++g ++ +++ FUN_000407-T4 598 DLK--TYTKYTITVYAEDKDGMRGAPAVT 624 333..489***********7666555544 PP >> fn3_4 Fibronectin-III type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 9.8 8.7e+03 37 64 .. 194 218 .. 185 231 .. 0.67 2 ? 2.8 0.0 0.17 1.5e+02 2 24 .. 441 463 .. 440 477 .. 0.93 3 ? -1.2 0.0 3 2.7e+03 72 93 .. 500 521 .. 496 528 .. 0.85 4 ? 5.4 0.0 0.026 23 2 61 .. 539 598 .. 538 620 .. 0.81 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 9.8 fn3_4 37 sYelflyqeetktssstdsWkkigdvkA 64 Ye f+++e +++ + + +g+vk FUN_000407-T4 194 KYECFATNEIARKTHT-S--TTVGNVKV 218 6889999884444433.2..35555555 PP == domain 2 score: 2.8 bits; conditional E-value: 0.17 fn3_4 2 pPqkpelkiakvevptgivlsWn 24 P+kpe +a+v ++t+i l+W FUN_000407-T4 441 FPEKPENVVAQVLSDTEIELTWS 463 69********************6 PP == domain 3 score: -1.2 bits; conditional E-value: 3 fn3_4 72 tlsqfkegkkyyfavrakDiyg 93 ++s++++++ y+f v ak +g FUN_000407-T4 500 QFSDLEPDTEYQFNVFAKNKHG 521 5789999**********99987 PP == domain 4 score: 5.4 bits; conditional E-value: 0.026 fn3_4 2 pPqkpelkiakvevptgivlsWnvekldpkaaevesYelflyqeetktssstdsWkkigd 61 +P kp+ +a+ ++++i ++W+v+++ p+ v Y+ ++e++ + +++++ + + d FUN_000407-T4 539 VPGKPRDLVAEAVTESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDNTKKQTRVLRD 598 68899989999999*************999999999987777777776666665555555 PP >> Y_Y_Y Y_Y_Y domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.027 24 39 57 .. 509 527 .. 509 534 .. 0.81 2 ? 4.1 0.0 0.071 63 39 51 .. 604 616 .. 602 627 .. 0.87 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.027 Y_Y_Y 39 kYtlkVkakdkdgnweydd 57 +Y++ V+ak+k g+ + ++ FUN_000407-T4 509 EYQFNVFAKNKHGTGAISE 527 7************988764 PP == domain 2 score: 4.1 bits; conditional E-value: 0.071 Y_Y_Y 39 kYtlkVkakdkdg 51 kYt++V+a dkdg FUN_000407-T4 604 KYTITVYAEDKDG 616 7**********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (633 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 835 (0.0326874); expected 510.9 (0.02) Passed bias filter: 706 (0.0276375); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 29 (0.00113525); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 29 [number of targets reported over threshold] # CPU time: 0.39u 0.37s 00:00:00.76 Elapsed: 00:00:00.48 # Mc/sec: 5306.16 // Query: FUN_000407-T5 [L=486] Description: FUN_000407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.4e-60 200.1 1.2 8.2e-16 58.7 0.0 4.4 4 Ig_3 Immunoglobulin domain 1.4e-59 198.6 0.1 2.8e-14 53.4 0.0 4.2 4 I-set Immunoglobulin I-set domain 1.2e-41 141.3 3.3 1e-11 45.3 0.0 4.2 4 Ig_2 Immunoglobulin domain 1.4e-31 109.1 5.5 3.4e-07 31.0 0.1 4.4 4 ig Immunoglobulin domain 2e-19 69.9 0.1 0.00038 20.9 0.0 4.6 4 C2-set_2 CD80-like C2-set immunoglobulin domain 2.7e-17 63.4 9.4 0.0028 18.3 0.2 7.7 6 V-set Immunoglobulin V-set domain 1.2e-10 42.1 0.1 2.5e-06 28.2 0.0 3.9 3 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 1.9e-10 41.1 0.2 1.2 9.7 0.0 4.3 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 1.9e-09 38.4 0.4 0.082 14.0 0.0 5.4 5 Ig_4 T-cell surface glycoprotein CD3 delta ch 4.5e-09 36.9 0.5 0.18 12.2 0.0 3.8 4 Ig_PDGFR_d4 Platelet-derived growth factor receptor 5.3e-08 33.6 0.4 0.57 11.0 0.0 4.6 4 C1-set Immunoglobulin C1-set domain 9e-05 23.2 0.3 1.6 9.4 0.0 4.4 4 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.00025 21.3 0.3 0.5 10.7 0.0 3.8 3 V-set_CD47 CD47 immunoglobulin-like domain 0.002 18.6 0.1 0.5 10.9 0.0 3.5 4 Sp38 Zona-pellucida-binding protein (Sp38) N- 0.0024 18.5 0.1 0.0098 16.6 0.0 2.1 1 fn3 Fibronectin type III domain 0.0025 18.7 0.0 18 6.4 0.0 3.6 3 Shr-like_HID Heme-binding protein Shr-like, Hb-intera ------ inclusion threshold ------ 0.021 15.2 0.0 1.1 9.5 0.0 2.8 2 Ig_6 Immunoglobulin domain 0.023 15.1 0.2 10 6.6 0.0 3.6 4 Izumo-Ig Izumo-like Immunoglobulin domain Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 0.1 1.4e-14 2e-11 2 76 .. 28 104 .. 28 105 .. 0.78 2 ! 40.9 0.0 2.1e-13 3e-10 6 78 .] 129 201 .. 126 201 .. 0.84 3 ! 58.7 0.0 5.8e-19 8.2e-16 5 77 .. 231 301 .. 225 301 .. 0.90 4 ! 51.1 0.0 1.4e-16 2e-13 2 77 .. 319 389 .. 318 389 .. 0.94 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 1.4e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskrsssssnstLtisnvtredsGtYtCvA 76 P + +ps+t v++ +++tL+C++ gnp p+itW++ngk+ l+s +t k s + +++ +++++ d+G Y+C+ FUN_000407-T5 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQvtLDSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEG 104 778889*********************************764333333322555555555555699*********85 PP == domain 2 score: 40.9 bits; conditional E-value: 2.1e-13 Ig_3 6 vspsstvveegesvtLtCea.egnppptitWykngke..lssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 v p++ +v+ g++++L C++ ++np+ ++ W+k+g++ +++ + n+ L+i+n+++e +G+Y+C A+N FUN_000407-T5 129 VVPKTLSVTFGDTARLFCNVkHSNPKAKVGWRKQGSNvsITT-----GdrFTLIPNGALQINNLRFEEQGKYECFATN 201 5577777999**********7777777*********653333.....23379*************************9 PP == domain 3 score: 58.7 bits; conditional E-value: 5.8e-19 Ig_3 5 tvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 ++ p++t+++ ++v+L+C a+g+p+p+itW+k+g e+s+g+ +s ++++L i++v +++GtYtC+As FUN_000407-T5 231 QARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNG--YSILGQGNLMIKSVAVSHAGTYTCRAS 301 47789999****************************98886666..79***********************97 PP == domain 4 score: 51.1 bits; conditional E-value: 1.4e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 Pv+t +ps++++ +++v+++C+aeg p+p+i+W+ ng+ + s s ++ ++L+++++ ++d G Y+C A+ FUN_000407-T5 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGR---ELSLS--YTRVVDGVLEVRDLVFSDKGVYQCFAK 389 9**************************************...66666..57899*******************995 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.9 0.0 8.8e-15 1.3e-11 1 88 [. 28 118 .. 28 120 .. 0.86 2 ! 43.0 0.0 3.5e-14 4.9e-11 2 85 .. 126 209 .. 125 213 .. 0.85 3 ! 53.4 0.0 2e-17 2.8e-14 2 90 .] 229 315 .. 228 315 .. 0.94 4 ! 52.2 0.0 4.6e-17 6.5e-14 1 90 [] 319 403 .. 319 403 .. 0.92 Alignments for each domain: == domain 1 score: 44.9 bits; conditional E-value: 8.8e-15 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee..gtatLtIsnvkkeDeGkYtckatns.ageaeasaeL 88 p+f ++++d+ v++ + a+l+c+v G+p p+++W+++g++++ ++r +k ++ ++++ ++ k DeG+Y+c+ + s ++ + +a++ FUN_000407-T5 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTLDSRRTIKPDGslYFTEIFHNRTHKPDEGIYQCEGSQSyYKIISRTARV 118 89***************************************************555556666889999*******9888744444555555 PP == domain 2 score: 43.0 bits; conditional E-value: 3.5e-14 I-set 2 kftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselke..skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 k++ +k ++v+ G++a+l c+v+ + p+ +v W k+gs+++ ++r+ + ++ L I+n++ e++GkY+c atn++ +++++ FUN_000407-T5 126 KVDVVPKTLSVTFGDTARLFCNVKHSnPKAKVGWRKQGSNVSIttGDRFTLIPNG---ALQINNLRFEEQGKYECFATNEIARKTHT 209 567789*****************9655**********776655338888888888...9*********************8777665 PP == domain 3 score: 53.4 bits; conditional E-value: 2e-17 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +f+ ++kd+ +++++++ lec +sG p+p+++Wlkdg e+++ ++ +++ ++ L+I++v + +G+Ytc+a+ + + a+a+L V FUN_000407-T5 229 SFQARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPgQNGYSILGQG---NLMIKSVAVSHAGTYTCRASQTTRSFDATAKLDV 315 6999**************************************66678888888...****************************999987 PP == domain 4 score: 52.2 bits; conditional E-value: 4.6e-17 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p ft+k++dv + ++++++ec+++G p+p++sW+ +g+el+ ++ ++ L+++++ +D+G Y+c a+ +g+++as +L V FUN_000407-T5 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSL--SYTRVVDG---VLEVRDLVFSDKGVYQCFAKGHSGKVQASGQLFV 403 78****************************************5..34444444...9***************************999876 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.2 0.1 8e-15 1.1e-11 5 79 .] 33 120 .. 29 120 .. 0.88 2 ! 24.5 0.1 2.3e-08 3.3e-05 10 75 .. 135 211 .. 125 218 .. 0.75 3 ! 45.3 0.0 7.3e-15 1e-11 5 67 .. 233 304 .. 229 315 .. 0.88 4 ! 24.1 0.0 3.2e-08 4.5e-05 6 71 .. 325 395 .. 318 403 .. 0.77 Alignments for each domain: == domain 1 score: 45.2 bits; conditional E-value: 8e-15 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn............fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++s+t v+++++ tL+C++ gnp +++tw ++gk + +s++ +f+++ + d G+Y+C+ +++ ++ s++ ++tv FUN_000407-T5 33 EPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTlDSRRtikpdgslyfteIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3666899**************************99888555557777889777777799**************************998 PP == domain 2 score: 24.5 bits; conditional E-value: 2.3e-08 Ig_2 10 vvtegesvtLtCsas.gnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnpv 75 vt g++ +L C ++ +np+ak+ w+k+g+ +s ++ + + ++n e +G Y C a+n+ k+ ++ FUN_000407-T5 135 SVTFGDTARLFCNVKhSNPKAKVGWRKQGSNVSiTTGDrftlipngaLQINNLRFEEQGKYECFATNEIARKTHTST 211 47889*********999************9999844444544444434468899************96665544444 PP == domain 3 score: 45.3 bits; conditional E-value: 7.3e-15 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn.........fftsnvsaedsGtYtCtarntk 67 ++ +t t+ ++v L C asg p++++tw kdg ++s++qn + +++v ++++GtYtC+a++t FUN_000407-T5 233 RPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNgysilgqgnLMIKSVAVSHAGTYTCRASQTT 304 4555778999*******************************999999988889***************9864 PP == domain 4 score: 24.1 bits; conditional E-value: 3.2e-08 Ig_2 6 asptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn.....fftsnvsaedsGtYtCtarntkggkv 71 +s+ + +++ v++ C+a g p+++++w +g++ls s+++ + ++ +d+G+Y+C a+ ++ gkv FUN_000407-T5 325 PSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSlSYTRvvdgvLEVRDLVFSDKGVYQCFAKGHS-GKV 395 44477899****************************88888555533356688*********998644.554 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.0 0.1 2.4e-10 3.4e-07 3 71 .. 37 105 .. 35 108 .. 0.86 2 ! 29.2 0.1 8.7e-10 1.2e-06 2 74 .. 133 203 .. 132 210 .. 0.90 3 ! 25.6 0.1 1.2e-08 1.6e-05 8 73 .. 242 303 .. 237 310 .. 0.91 4 ! 23.1 0.0 6.7e-08 9.5e-05 5 79 .. 330 397 .. 326 398 .. 0.92 Alignments for each domain: == domain 1 score: 31.0 bits; conditional E-value: 2.4e-10 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk.vkedngrttqssllisnvteedaGtYtCvvn 71 ++v++++ atL C + g+p p++tW+++gk+ ++ ++ + + +g+ + +++ +++ + d+G Y C+++ FUN_000407-T5 37 TYVRKSKPATLKCQVG-GNPLPSITWKRNGKQVTLDSRrTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGS 105 789999**********.*********************64444455555589999999*********997 PP == domain 2 score: 29.2 bits; conditional E-value: 8.7e-10 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 t+ v G++a+L C++++++p + v W+k+g+ ++ + ++ + + l+i+n ++e G Y C ++n+ FUN_000407-T5 133 TLSVTFGDTARLFCNVKHSNPKAKVGWRKQGSNVSITTG--DRFTLIPNGALQINNLRFEEQGKYECFATNEI 203 67899*************************998777766..778888888*******************9975 PP == domain 3 score: 25.6 bits; conditional E-value: 1.2e-08 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++++L C as g p p++tW k+g ++ ++ ++ +q +l i +v ++aGtYtC+++ + FUN_000407-T5 242 ESTVVLECVAS-GYPKPSITWLKDGFEISPGQN---GYSILGQGNLMIKSVAVSHAGTYTCRASQT 303 689********.*************99999988...88888999******************9865 PP == domain 4 score: 23.1 bits; conditional E-value: 6.7e-08 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 +++ +++++ C a+ g p p+++Ws +g ++ +s + r+ + l +++ ++d G Y C + ++g++++ FUN_000407-T5 330 AYRNSRVRFECQAE-GIPKPNISWSLNGRELSLSYT------RVVDGVLEVRDLVFSDKGVYQCFAKGHSGKVQA 397 678899********.***************999955......*************************99999887 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 2.4e-06 0.0034 15 72 .. 43 97 .. 30 106 .. 0.75 2 ! 9.2 0.0 0.0012 1.8 14 45 .. 139 169 .. 127 195 .. 0.77 3 ! 20.9 0.0 2.7e-07 0.00038 5 41 .. 234 268 .. 231 308 .. 0.81 4 ! 16.0 0.0 9.1e-06 0.013 9 44 .. 327 362 .. 319 370 .. 0.77 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 2.4e-06 C2-set_2 15 kevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredn 72 k +++C gg+P p+itW ++gk++ + ++++++p+ l+ + + ++ ++++ d FUN_000407-T5 43 KPATLKC-QVGGNPLPSITWKRNGKQV-TLDSRRTIKPDGSLYFT-EIFHNRTHKPDE 97 5678899.679***************9.77777777777777766.888888887665 PP == domain 2 score: 9.2 bits; conditional E-value: 0.0012 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaae 45 + + + C ++ ++P++++ W ++g ++ ++ FUN_000407-T5 139 GDTARLFCNVKHSNPKAKVGWRKQGSNV-SIT 169 4567778******************998.443 PP == domain 3 score: 20.9 bits; conditional E-value: 2.7e-07 C2-set_2 5 psaslleaeekevvatCvsaggkPapritWlldgkel 41 p++++ ++e +vv++C +a+g+P+p+itWl+dg e+ FUN_000407-T5 234 PKDTMATTE-STVVLEC-VASGYPKPSITWLKDGFEI 268 455555565.99*****.899************9776 PP == domain 4 score: 16.0 bits; conditional E-value: 9.1e-06 C2-set_2 9 lleae.ekevvatCvsaggkPapritWlldgkeleaa 44 + a + +v ++C a+g P+p+i+W l+g+el+ + FUN_000407-T5 327 DVHAYrNSRVRFEC-QAEGIPKPNISWSLNGRELSLS 362 44444678999***.999***************9443 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.077 1.1e+02 2 39 .. 33 67 .. 32 81 .. 0.84 2 ! 8.0 0.1 0.0032 4.6 78 108 .. 90 120 .. 63 121 .. 0.69 3 ! 16.2 0.1 8.8e-06 0.013 2 99 .. 130 209 .. 129 219 .. 0.72 4 ! 18.3 0.2 2e-06 0.0028 59 108 .. 272 315 .. 232 316 .. 0.78 5 ? 0.7 0.0 0.6 8.5e+02 2 36 .. 324 355 .. 323 364 .. 0.85 6 ! 10.0 0.0 0.00074 1 69 104 .. 365 399 .. 356 404 .. 0.73 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.077 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrqppg 39 +p+ + v + +tL+C++ + + s++W r ++ FUN_000407-T5 33 EPSDTYVRKSKPATLKCQVGGN---PLPSITWKRNGKQ 67 577777888999*******999...*******997654 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0032 V-set 78 qnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + + D+G+Y+C+ +++ +++ r+tV FUN_000407-T5 90 NRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 456788********65555556999999998 PP == domain 3 score: 16.2 bits; conditional E-value: 8.8e-06 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekk.kgrfslrkdpsrsdfsltiqnltlsDsGtYtCav...i 93 +p++++v G +++L C ++ s ++ +v W +q ++ ++++ ++rf+l ++ l+i+nl+ + +G Y+C + i FUN_000407-T5 130 VPKTLSVTFGDTARLFCNVKHS--NPKAKVGWRKQGSN---------------VSITtGDRFTLIP-----NGALQINNLRFEEQGKYECFAtneI 203 5778888888888888877755..78888888887754...............3444499******.....*******************953333 PP V-set 94 pkgevv 99 +++++ FUN_000407-T5 204 ARKTHT 209 333333 PP == domain 4 score: 18.3 bits; conditional E-value: 2e-06 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 ++ +s+ + + l i+++ +s++GtYtC+ ++ + +f ++ +L V FUN_000407-T5 272 QNGYSILG-----QGNLMIKSVAVSHAGTYTCR-ASQTTRSFDATAKLDV 315 56666666.....99******************.8999999999998877 PP == domain 5 score: 0.7 bits; conditional E-value: 0.6 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrq 36 +p+ v++ ++ +v++ C+ + ++W+ FUN_000407-T5 324 KPSDVHAYRNSRVRFECQAEGI---PKPNISWSLN 355 68999************98887...9999999875 PP == domain 6 score: 10.0 bits; conditional E-value: 0.00074 V-set 69 srsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 + d+ l++++l sD G+Y+C + + +++ +++ FUN_000407-T5 365 RVVDGVLEVRDLVFSDKGVYQCFA-KGHSGKVQASG 399 566999****************94.44444444444 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.0 1.7e-09 2.5e-06 4 47 .. 25 70 .. 22 90 .. 0.84 2 ? 0.7 0.0 0.63 8.9e+02 8 30 .. 229 251 .. 223 255 .. 0.90 3 ! 7.6 0.0 0.0044 6.2 7 31 .. 319 343 .. 314 369 .. 0.86 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.7e-09 Unc5_NetrinR_N 4 eelPifleePedayivknkpvtLkCka..akalqiyFkCngewvee 47 ++lP+f+eeP+d+y+ k+kp+tLkC++ + i +k ng++v+ FUN_000407-T5 25 ADLPHFIEEPSDTYVRKSKPATLKCQVggNPLPSITWKRNGKQVTL 70 579**********************983356678888888888765 PP == domain 2 score: 0.7 bits; conditional E-value: 0.63 Unc5_NetrinR_N 8 ifleePedayivknkpvtLkCka 30 f P+d+ + v+L+C a FUN_000407-T5 229 SFQARPKDTMATTESTVVLECVA 251 58899****************88 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0044 Unc5_NetrinR_N 7 PifleePedayivknkpvtLkCkaa 31 P+f ++P+d++ +n v ++C+a+ FUN_000407-T5 319 PVFTKKPSDVHAYRNSRVRFECQAE 343 9**********************96 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.0013 1.9 15 57 .. 43 83 .. 36 102 .. 0.74 2 ! 8.7 0.0 0.0017 2.4 15 82 .. 140 204 .. 133 209 .. 0.79 3 ! 8.3 0.0 0.0023 3.2 13 37 .. 241 264 .. 235 304 .. 0.71 4 ! 9.7 0.0 0.00083 1.2 9 42 .. 328 359 .. 324 386 .. 0.79 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0013 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglf 57 + +l+C++ G++P P++ W+ + +++ + ++++d+ l+ FUN_000407-T5 43 KPATLKCQV-GGNPLPSITWKRNGKQVTLDSRRTIKPDG-SLY 83 566899996.779*******9987776666666666664.344 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0017 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpll 82 + rl C+++ +P+ +v Wr++ ++ ++ ++ +g ++++ r + +++++C+ +n++ FUN_000407-T5 140 DTARLFCNVKHSNPKAKVGWRKQGSNVSITTGDRFTLIPNGALQINNL---RFEEQGKYECFATNEIA 204 56799****************987777667777788888888888774...44667888888888776 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0023 C2-set_3 13 edggirlvCrsaGWyPePqvqWrde 37 + + l+C ++G yP+P++ W + FUN_000407-T5 241 TESTVVLECVASG-YPKPSITWLKD 264 567899***9998.********754 PP == domain 4 score: 9.7 bits; conditional E-value: 0.00083 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekgekl 42 v+ y++ +r +C+++G P+P+++W + g++l FUN_000407-T5 328 VHAYRNSRVRFECQAEG-IPKPNISWSLN-GREL 359 678999*********99.7*******754.4444 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 4.4 6.2e+03 32 47 .. 25 40 .. 20 48 .. 0.81 2 ! 7.6 0.2 0.0058 8.2 5 51 .. 46 106 .. 42 118 .. 0.65 3 ? 3.4 0.0 0.11 1.6e+02 31 52 .. 181 202 .. 139 213 .. 0.62 4 ! 14.0 0.0 5.8e-05 0.082 2 54 .. 243 305 .. 242 317 .. 0.77 5 ? 6.2 0.0 0.016 22 4 62 .. 336 405 .. 333 406 .. 0.70 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 4.4 Ig_4 32 ldlgksiedprglYqC 47 dl ++ie+p+ +Y+ FUN_000407-T5 25 ADLPHFIEEPSDTYVR 40 58999********975 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0058 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek...........tldlgksiedprglYqCkeee 51 +L+C+ +itw+++gk+ + +++ ++ +++ + ++g+YqC++++ FUN_000407-T5 46 TLKCQVGGnplPSITWKRNGKQVTLDSRRtikpdgslyftEIFHNRTHKPDEGIYQCEGSQ 106 67885443124579999999999888877566666444422333344457899****9743 PP == domain 3 score: 3.4 bits; conditional E-value: 0.11 Ig_4 31 tldlgksiedprglYqCkeeek 52 l++++ +++g Y+C +++ FUN_000407-T5 181 ALQINNLRFEEQGKYECFATNE 202 788888888********94333 PP == domain 4 score: 14.0 bits; conditional E-value: 5.8e-05 Ig_4 2 dkVlLtCnsss...keitwlkdgkeikeskek.......tldlgksiedprglYqCkeeekkk 54 +V+L+C s +itwlkdg ei+ ++ +l ++++ g+Y+C+ +++++ FUN_000407-T5 243 STVVLECVASGypkPSITWLKDGFEISPGQNGysilgqgNLMIKSVAVSHAGTYTCRASQTTR 305 68*****444333368**********9998877788878889999999********9644443 PP == domain 5 score: 6.2 bits; conditional E-value: 0.016 Ig_4 4 VlLtCnsss...keitwlkdgkeikeskek....tldlgksiedprglYqCk....eeekkkssslqvyy 62 V +C+ + +i w +g e + s ++ l++ + + ++g+YqC + + ++s +l vyy FUN_000407-T5 336 VRFECQAEGipkPNISWSLNGRELSLSYTRvvdgVLEVRDLVFSDKGVYQCFakghSGKVQASGQLFVYY 405 555665443322578999999999988888777778888888899******9776533555666677776 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.0022 3.2 11 33 .. 40 62 .. 30 137 .. 0.73 2 ? -2.5 0.0 4.7 6.6e+03 84 104 .. 189 209 .. 179 216 .. 0.74 3 ! 12.2 0.0 0.00013 0.18 12 33 .. 241 262 .. 232 267 .. 0.80 4 ! 11.9 0.0 0.00017 0.24 9 33 .. 329 353 .. 322 357 .. 0.79 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0022 Ig_PDGFR_d4 11 assgeqtvtCvaeGmPqPeveWf 33 +s+ t++C G P P+++W FUN_000407-T5 40 RKSKPATLKCQVGGNPLPSITWK 62 5677789***************6 PP == domain 2 score: -2.5 bits; conditional E-value: 4.7 Ig_PDGFR_d4 84 veetlavrCeaknelgadsre 104 ee+ C a+ne++++++ FUN_000407-T5 189 FEEQGKYECFATNEIARKTHT 209 566777789999999988765 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00013 Ig_PDGFR_d4 12 ssgeqtvtCvaeGmPqPeveWf 33 +++ ++ Cva G+P+P+++W+ FUN_000407-T5 241 TESTVVLECVASGYPKPSITWL 262 44555678*************7 PP == domain 4 score: 11.9 bits; conditional E-value: 0.00017 Ig_PDGFR_d4 9 shassgeqtvtCvaeGmPqPeveWf 33 + +++ C aeG+P+P+++W FUN_000407-T5 329 HAYRNSRVRFECQAEGIPKPNISWS 353 34456677789*************7 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.0 0.0 0.0004 0.57 12 61 .. 41 86 .. 30 106 .. 0.65 2 ? 6.2 0.0 0.014 19 4 43 .. 130 168 .. 127 202 .. 0.75 3 ! 10.0 0.0 0.00085 1.2 5 46 .. 234 273 .. 230 304 .. 0.72 4 ? 0.1 0.0 1.1 1.5e+03 13 43 .. 333 361 .. 320 368 .. 0.66 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.0004 C1-set 12 kgkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqll 61 k+k++tL C v g p ++tW++ng++vt ++ +k ++s y++ FUN_000407-T5 41 KSKPATLKCQVGGN--PLPSITWKRNGKQVTL--DSRRTIKPDGSLYFTE 86 3899*******984..344789*********6..6666666666666654 PP == domain 2 score: 6.2 bits; conditional E-value: 0.014 C1-set 4 lppspeelkgkkntLvClvtgfyPpdikVtWlkngqevte 43 +p++ + + g+++ L C v+ P + kV W k+g++v+ FUN_000407-T5 130 VPKTLSVTFGDTARLFCNVKHSNP-KAKVGWRKQGSNVSI 168 555555555999*******98777.89********99985 PP == domain 3 score: 10.0 bits; conditional E-value: 0.00085 C1-set 5 ppspeelkgkkntLvClvtgfyPpdikVtWlkngqevtegvk 46 p+++ +++++++L C+++g+ p ++tWlk+g e++ g + FUN_000407-T5 234 PKDTMATTESTVVLECVASGYPKP--SITWLKDGFEISPGQN 273 5555666799**********9666..679*****99998644 PP == domain 4 score: 0.1 bits; conditional E-value: 1.1 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevte 43 ++ + C ++g+ p +++W ng+e++ FUN_000407-T5 333 NSRVRFECQAEGIPKP--NISWSLNGRELSL 361 5556666777776444..678999*999875 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.12 1.7e+02 20 42 .. 40 62 .. 32 122 .. 0.89 2 ? -1.6 0.0 2.9 4.1e+03 104 119 .. 192 207 .. 185 211 .. 0.86 3 ? 5.1 0.0 0.025 36 26 45 .. 246 265 .. 231 289 .. 0.85 4 ! 9.4 0.0 0.0011 1.6 19 47 .. 331 358 .. 311 368 .. 0.77 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.12 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwf 42 r + l c g p+p itw FUN_000407-T5 40 RKSKPATLKCQVGGNPLPSITWK 62 555566799*************6 PP == domain 2 score: -1.6 bits; conditional E-value: 2.9 Ig_VEGFR-1-like_5th 104 sgvysctarnelgnrt 119 g y c a ne+ +t FUN_000407-T5 192 QGKYECFATNEIARKT 207 589********99887 PP == domain 3 score: 5.1 bits; conditional E-value: 0.025 Ig_VEGFR-1-like_5th 26 kltctafgipmpnitwfwqp 45 l c a g p p itw+ + FUN_000407-T5 246 VLECVASGYPKPSITWLKDG 265 589*************9765 PP == domain 4 score: 9.4 bits; conditional E-value: 0.0011 Ig_VEGFR-1-like_5th 19 frydqrhkltctafgipmpnitwfwqpcd 47 +r + r ++ c a gip pni+w + + FUN_000407-T5 331 YR-NSRVRFECQAEGIPKPNISWSLNGRE 358 33.568999**************876655 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.4 0.022 31 28 92 .. 140 205 .. 44 217 .. 0.82 2 ! 10.7 0.0 0.00035 0.5 27 101 .. 242 315 .. 227 326 .. 0.67 3 ? -0.0 0.0 0.74 1e+03 27 62 .. 333 363 .. 320 401 .. 0.67 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.022 V-set_CD47 28 dtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst....Lkldfsd.alsGnYtCevtelsne 92 dt + C+v++ + ++ v W+ +++++ i + + + + L++++ + +G Y C +t++ + FUN_000407-T5 140 DTARLFCNVKH----SNPKAKVGWRKQGSNVSITTGDRFTLIpngaLQINNLRfEEQGKYECFATNEIAR 205 66777888866....44678899999999999988885555588886665543145899*9999887653 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00035 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst.....Lkld.fsdalsGnYtCevtelsnevkttieLkl 101 +tvv+eC + ++ + W ++ +i ++ s+ L ++ + +G+YtC +++++++ t +L + FUN_000407-T5 242 ESTVVLECVASGYPKP-----SITWLKDGFEISPGQNGY--SIlgqgnLMIKsVAVSHAGTYTCRASQTTRSFDATAKLDV 315 6777888877664444.....457777777766544432..222355544441455679***************9999987 PP == domain 3 score: -0.0 bits; conditional E-value: 0.74 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisn 62 n+ v eC+ + +++ n ++W++n++++ s FUN_000407-T5 333 NSRVRFECQAEGIPKPN-----ISWSLNGRELSLSY 363 67777788776666655.....59999998876554 PP >> Sp38 Zona-pellucida-binding protein (Sp38) N-terminal Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.61 8.7e+02 32 79 .. 59 113 .. 56 122 .. 0.64 2 ? 2.1 0.0 0.19 2.7e+02 42 79 .. 168 205 .. 152 218 .. 0.73 3 ! 10.9 0.0 0.00035 0.5 30 83 .. 257 310 .. 244 322 .. 0.83 4 ? -2.5 0.0 5.3 7.5e+03 54 73 .. 369 388 .. 348 401 .. 0.73 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.61 Sp38 32 ylWiGPdgkllsgnssinitetGelvlkd.f....eeslsGvytctls...ykivk 79 +W+ +gk+++ +s+ i + G+l +++ f +++ G+y c s yki++ FUN_000407-T5 59 ITWK-RNGKQVTLDSRRTIKPDGSLYFTEiFhnrtHKPDEGIYQCEGSqsyYKIIS 113 5665.478999999999999999998876231111234468898864322255554 PP == domain 2 score: 2.1 bits; conditional E-value: 0.19 Sp38 42 lsgnssinitetGelvlkdfeeslsGvytctlsykivk 79 ++ ++ + + G l +++++ + G y c+ + i + FUN_000407-T5 168 ITTGDRFTLIPNGALQINNLRFEEQGKYECFATNEIAR 205 344456778899******************98766544 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00035 Sp38 30 PvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctlsykivkaeaq 83 P+ +W +++ g++ i + G+l++k s +G+ytc s + + +a+ FUN_000407-T5 257 PSITWLKDGFEISPGQNGYSILGQGNLMIKSVAVSHAGTYTCRASQTTRSFDAT 310 66777777777888999999**********************988766555555 PP == domain 4 score: -2.5 bits; conditional E-value: 5.3 Sp38 54 GelvlkdfeeslsGvytctl 73 G l ++d+ s Gvy c+ FUN_000407-T5 369 GVLEVRDLVFSDKGVYQCFA 388 55666666667778888875 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 6.9e-06 0.0098 2 38 .. 443 480 .. 442 484 .. 0.89 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 6.9e-06 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrp 38 +P+n+ ++ ++t+++++W+pp ++g+i +Y y + FUN_000407-T5 443 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVK 480 7******99999***********99*******877765 PP >> Shr-like_HID Heme-binding protein Shr-like, Hb-interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.012 18 23 64 .. 158 196 .. 134 197 .. 0.87 2 ? 5.9 0.0 0.018 26 34 64 .. 264 297 .. 235 301 .. 0.83 3 ? 1.6 0.0 0.4 5.7e+02 32 64 .. 353 385 .. 347 387 .. 0.86 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.012 Shr-like_HID 23 aWrsaitevkvnGtelssdkYti.eagkitldagvftkageyt 64 Wr++ ++v++ t+ +d++t+ +g +++++ f+++g+y+ FUN_000407-T5 158 GWRKQGSNVSI--TT--GDRFTLiPNGALQINNLRFEEQGKYE 196 79999999999..44..777**9988**************997 PP == domain 2 score: 5.9 bits; conditional E-value: 0.018 Shr-like_HID 34 nGtelssdk..Yti.eagkitldagvftkageyt 64 +G e+s+++ Y+i +g++ +++ + ++ag+yt FUN_000407-T5 264 DGFEISPGQngYSIlGQGNLMIKSVAVSHAGTYT 297 77777756556****88****************8 PP == domain 3 score: 1.6 bits; conditional E-value: 0.4 Shr-like_HID 32 kvnGtelssdkYti.eagkitldagvftkageyt 64 ++nG els + Yt +g +++ + vf+ +g y+ FUN_000407-T5 353 SLNGRELSLS-YTRvVDGVLEVRDLVFSDKGVYQ 385 579***9999.887789**********9999885 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.14 2e+02 43 92 .. 154 199 .. 136 218 .. 0.67 2 ? 9.5 0.0 0.00081 1.1 68 93 .. 276 301 .. 235 313 .. 0.82 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.14 Ig_6 43 ksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 k +V W +q ++ i+ + aL+++ ++ ++ G Y C FUN_000407-T5 154 KAKVGWRKQGSNV----SITTGDRFTLIPNGALQINNLRFEEQGKYECFA 199 5566665544332....33444444556788999999999******9975 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00081 Ig_6 68 iileknaLrfkpvkvndsGlYiCrpr 93 il + +L +k+v v+++G+Y Cr FUN_000407-T5 276 SILGQGNLMIKSVAVSHAGTYTCRAS 301 5678899****************953 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 4 5.6e+03 59 67 .. 95 103 .. 88 121 .. 0.73 2 ? 6.6 0.0 0.0073 10 50 87 .. 181 220 .. 160 221 .. 0.74 3 ? 2.9 0.0 0.11 1.5e+02 51 72 .. 283 304 .. 276 315 .. 0.78 4 ? 0.2 0.0 0.75 1.1e+03 50 68 .. 370 388 .. 356 411 .. 0.72 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 4 Izumo-Ig 59 edaGtYRCe 67 d+G Y Ce FUN_000407-T5 95 PDEGIYQCE 103 588999997 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0073 Izumo-Ig 50 tLtkpmvgledaGtYRCeLdt.v.ksspatiihfkvtvlp 87 +L + +++e++G+Y C + + ++++ +v+vlp FUN_000407-T5 181 ALQINNLRFEEQGKYECFATNeIaRKTHTSTTVGNVKVLP 220 688899***********75431346666666667777777 PP == domain 3 score: 2.9 bits; conditional E-value: 0.11 Izumo-Ig 51 LtkpmvgledaGtYRCeLdtvk 72 L + v++ aGtY C + FUN_000407-T5 283 LMIKSVAVSHAGTYTCRASQTT 304 6667899*********876654 PP == domain 4 score: 0.2 bits; conditional E-value: 0.75 Izumo-Ig 50 tLtkpmvgledaGtYRCeL 68 +L + + d+G+Y C FUN_000407-T5 370 VLEVRDLVFSDKGVYQCFA 388 5556667889*******64 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (486 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 593 (0.0232139); expected 510.9 (0.02) Passed bias filter: 538 (0.0210609); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.36u 0.33s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4835.58 // Query: FUN_000407-T6 [L=632] Description: FUN_000407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-59 197.4 0.5 4.1e-14 52.9 0.0 5.0 5 I-set Immunoglobulin I-set domain 4.8e-59 197.3 4.3 1.2e-15 58.2 0.0 5.3 5 Ig_3 Immunoglobulin domain 3.9e-41 139.7 3.1 1.5e-11 44.8 0.0 4.4 4 Ig_2 Immunoglobulin domain 7.9e-30 103.5 10.5 4.9e-07 30.4 0.1 5.2 5 ig Immunoglobulin domain 1.8e-29 102.2 2.1 2.1e-13 50.8 0.4 2.9 2 fn3 Fibronectin type III domain 7.3e-19 68.1 0.1 0.00055 20.4 0.0 4.7 4 C2-set_2 CD80-like C2-set immunoglobulin domain 2.6e-16 60.2 12.4 0.004 17.8 0.2 8.6 6 V-set Immunoglobulin V-set domain 3.1e-10 40.8 0.0 3.5e-06 27.7 0.0 3.8 3 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 6.4e-10 39.4 0.1 1.7 9.2 0.0 4.4 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 6.8e-09 36.6 0.3 0.12 13.4 0.0 5.6 4 Ig_4 T-cell surface glycoprotein CD3 delta ch 1.2e-08 35.6 0.5 0.25 11.8 0.0 3.9 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor 1.6e-08 35.2 0.3 0.00089 20.0 0.0 2.7 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 6.1e-07 30.2 2.8 0.83 10.5 0.0 5.0 4 C1-set Immunoglobulin C1-set domain 2.2e-06 28.6 2.4 0.067 14.3 0.0 3.6 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal doma 0.00024 21.8 0.0 2.2 9.0 0.0 4.2 4 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.00077 19.7 0.3 0.74 10.1 0.0 3.8 4 V-set_CD47 CD47 immunoglobulin-like domain 0.00093 19.3 0.2 0.0017 18.4 0.2 1.4 1 DUF4998 Domain of unknown function 0.0013 19.4 0.1 0.081 13.7 0.1 2.6 2 Interfer-bind Interferon-alpha/beta receptor, fibronec 0.0031 18.4 0.0 25 5.9 0.0 4.1 4 Shr-like_HID Heme-binding protein Shr-like, Hb-intera 0.0041 17.6 0.1 0.74 10.3 0.0 3.6 3 Sp38 Zona-pellucida-binding protein (Sp38) N- 0.0049 17.4 0.1 0.82 10.2 0.0 2.5 2 NDNF Neuron-derived neurotrophic factor, firs 0.0051 17.3 0.4 0.17 12.5 0.1 2.7 2 InlK_D3 Internalin K domain (D3/D4) ------ inclusion threshold ------ 0.03 14.6 0.8 4.4 7.6 0.2 2.4 2 GH101_dom-5 Endo-alpha-N-acetylgalactosaminidase, do 0.031 15.2 0.7 45 5.0 0.1 3.7 3 Cadherin Cadherin domain 0.039 14.3 0.0 1.6 9.0 0.0 2.8 2 Ig_6 Immunoglobulin domain 0.057 14.0 0.3 0.22 12.1 0.2 2.1 2 Ig_J Tip attachment protein J, Ig-like domain 0.074 13.5 0.1 23 5.4 0.0 3.8 4 fn3_4 Fibronectin-III type domain 0.076 13.4 0.1 0.2 12.1 0.1 1.7 1 Monellin Monellin 0.091 13.2 0.3 13 6.3 0.1 2.7 2 Y_Y_Y Y_Y_Y domain Domain annotation for each model (and alignments): >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.4 0.0 2.1e-14 1.9e-11 1 88 [. 28 118 .. 28 120 .. 0.86 2 ! 42.5 0.0 8.4e-14 7.4e-11 2 85 .. 126 209 .. 125 213 .. 0.85 3 ! 52.9 0.0 4.7e-17 4.1e-14 2 90 .] 229 315 .. 228 315 .. 0.94 4 ! 51.7 0.0 1.1e-16 9.6e-14 1 90 [] 319 403 .. 319 403 .. 0.92 5 ? -1.9 0.0 5.6 4.9e+03 12 40 .. 537 565 .. 526 584 .. 0.71 Alignments for each domain: == domain 1 score: 44.4 bits; conditional E-value: 2.1e-14 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee..gtatLtIsnvkkeDeGkYtckatns.ageaeasaeL 88 p+f ++++d+ v++ + a+l+c+v G+p p+++W+++g++++ ++r +k ++ ++++ ++ k DeG+Y+c+ + s ++ + +a++ FUN_000407-T6 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTLDSRRTIKPDGslYFTEIFHNRTHKPDEGIYQCEGSQSyYKIISRTARV 118 89***************************************************555556666889999*******9888744444555555 PP == domain 2 score: 42.5 bits; conditional E-value: 8.4e-14 I-set 2 kftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselke..skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 k++ +k ++v+ G++a+l c+v+ + p+ +v W k+gs+++ ++r+ + ++ L I+n++ e++GkY+c atn++ +++++ FUN_000407-T6 126 KVDVVPKTLSVTFGDTARLFCNVKHSnPKAKVGWRKQGSNVSIttGDRFTLIPNG---ALQINNLRFEEQGKYECFATNEIARKTHT 209 567789*****************9655**********776655338888888888...9*********************8777665 PP == domain 3 score: 52.9 bits; conditional E-value: 4.7e-17 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +f+ ++kd+ +++++++ lec +sG p+p+++Wlkdg e+++ ++ +++ ++ L+I++v + +G+Ytc+a+ + + a+a+L V FUN_000407-T6 229 SFQARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPgQNGYSILGQG---NLMIKSVAVSHAGTYTCRASQTTRSFDATAKLDV 315 6999**************************************66678888888...***************************9999987 PP == domain 4 score: 51.7 bits; conditional E-value: 1.1e-16 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p ft+k++dv + ++++++ec+++G p+p++sW+ +g+el+ ++ ++ L+++++ +D+G Y+c a+ +g+++as +L V FUN_000407-T6 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSL--SYTRVVDG---VLEVRDLVFSDKGVYQCFAKGHSGKVQASGQLFV 403 78****************************************5..34444444...9***************************999876 PP == domain 5 score: -1.9 bits; conditional E-value: 5.6 I-set 12 vkeGesaeleckvsGepepevsWlkdgse 40 + G+ +l +++ e ++v+W ++ FUN_000407-T6 537 AVPGKPRDLVAEAVTESSIRVTWEVPDTG 565 55677778888888899999999988654 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.1 3.3e-14 2.9e-11 2 76 .. 28 104 .. 28 105 .. 0.78 2 ! 40.4 0.0 5e-13 4.4e-10 6 78 .] 129 201 .. 126 201 .. 0.84 3 ! 58.2 0.0 1.4e-18 1.2e-15 5 77 .. 231 301 .. 225 301 .. 0.90 4 ! 50.6 0.0 3.2e-16 2.9e-13 2 77 .. 319 389 .. 318 389 .. 0.94 5 ? 0.4 0.1 1.5 1.4e+03 11 51 .. 535 576 .. 527 608 .. 0.63 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 3.3e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskrsssssnstLtisnvtredsGtYtCvA 76 P + +ps+t v++ +++tL+C++ gnp p+itW++ngk+ l+s +t k s + +++ +++++ d+G Y+C+ FUN_000407-T6 28 PHFIEEPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQvtLDSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEG 104 778889*********************************764333333322555555555555699*********85 PP == domain 2 score: 40.4 bits; conditional E-value: 5e-13 Ig_3 6 vspsstvveegesvtLtCea.egnppptitWykngke..lssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 v p++ +v+ g++++L C++ ++np+ ++ W+k+g++ +++ + n+ L+i+n+++e +G+Y+C A+N FUN_000407-T6 129 VVPKTLSVTFGDTARLFCNVkHSNPKAKVGWRKQGSNvsITT-----GdrFTLIPNGALQINNLRFEEQGKYECFATN 201 5577777999**********7777777*********653333.....23379*************************9 PP == domain 3 score: 58.2 bits; conditional E-value: 1.4e-18 Ig_3 5 tvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 ++ p++t+++ ++v+L+C a+g+p+p+itW+k+g e+s+g+ +s ++++L i++v +++GtYtC+As FUN_000407-T6 231 QARPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNG--YSILGQGNLMIKSVAVSHAGTYTCRAS 301 47789999****************************98886666..79***********************97 PP == domain 4 score: 50.6 bits; conditional E-value: 3.2e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 Pv+t +ps++++ +++v+++C+aeg p+p+i+W+ ng+ + s s ++ ++L+++++ ++d G Y+C A+ FUN_000407-T6 319 PVFTKKPSDVHAYRNSRVRFECQAEGIPKPNISWSLNGR---ELSLS--YTRVVDGVLEVRDLVFSDKGVYQCFAK 389 9**************************************...66666..57899*******************995 PP == domain 5 score: 0.4 bits; conditional E-value: 1.5 Ig_3 11 tvveegesvtLtCeaegnppptitWykngkelssgstskr...s 51 +++++g++ L ea +++ ++tW +++ ++s++ FUN_000407-T6 535 SSAVPGKPRDLVAEAVTESSIRVTWEVPDT--GPVSRYVIlykD 576 445678888888888777777999998888..343333335432 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 0.1 1.9e-14 1.7e-11 5 79 .] 33 120 .. 29 120 .. 0.88 2 ! 23.9 0.1 5.7e-08 5e-05 11 74 .. 136 210 .. 126 218 .. 0.75 3 ! 44.8 0.0 1.7e-14 1.5e-11 5 67 .. 233 304 .. 229 315 .. 0.88 4 ! 23.6 0.0 7.5e-08 6.6e-05 6 71 .. 325 395 .. 318 403 .. 0.77 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 1.9e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn............fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++s+t v+++++ tL+C++ gnp +++tw ++gk + +s++ +f+++ + d G+Y+C+ +++ ++ s++ ++tv FUN_000407-T6 33 EPSDTYVRKSKPATLKCQVGGNPLPSITWKRNGKQVTlDSRRtikpdgslyfteIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3666899**************************99888555557777889777777799**************************998 PP == domain 2 score: 23.9 bits; conditional E-value: 5.7e-08 Ig_2 11 vtegesvtLtCsas.gnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnp 74 vt g++ +L C ++ +np+ak+ w+k+g+ +s ++ + + ++n e +G Y C a+n+ k+ + FUN_000407-T6 136 VTFGDTARLFCNVKhSNPKAKVGWRKQGSNVSiTTGDrftlipngaLQINNLRFEEQGKYECFATNEIARKTHTS 210 7889*********999************9999844444544444434468899************9666554444 PP == domain 3 score: 44.8 bits; conditional E-value: 1.7e-14 Ig_2 5 tasptvvtegesvtLtCsasgnppakytwykdgkvlsssqn.........fftsnvsaedsGtYtCtarntk 67 ++ +t t+ ++v L C asg p++++tw kdg ++s++qn + +++v ++++GtYtC+a++t FUN_000407-T6 233 RPKDTMATTESTVVLECVASGYPKPSITWLKDGFEISPGQNgysilgqgnLMIKSVAVSHAGTYTCRASQTT 304 4555778999*******************************999999988889***************9864 PP == domain 4 score: 23.6 bits; conditional E-value: 7.5e-08 Ig_2 6 asptvvtegesvtLtCsasgnppakytwykdgkvls.ssqn.....fftsnvsaedsGtYtCtarntkggkv 71 +s+ + +++ v++ C+a g p+++++w +g++ls s+++ + ++ +d+G+Y+C a+ ++ gkv FUN_000407-T6 325 PSDVHAYRNSRVRFECQAEGIPKPNISWSLNGRELSlSYTRvvdgvLEVRDLVFSDKGVYQCFAKGHS-GKV 395 44477899****************************88888555533356688*********998644.554 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.1 5.6e-10 4.9e-07 3 71 .. 37 105 .. 35 108 .. 0.86 2 ! 28.6 0.1 2.2e-09 1.9e-06 2 74 .. 133 203 .. 132 209 .. 0.90 3 ! 25.1 0.1 2.7e-08 2.4e-05 8 73 .. 242 303 .. 237 310 .. 0.91 4 ! 22.6 0.0 1.6e-07 0.00014 5 79 .. 330 397 .. 326 398 .. 0.92 5 ? -1.9 0.0 7.1 6.2e+03 21 38 .. 552 569 .. 545 593 .. 0.62 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 5.6e-10 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk.vkedngrttqssllisnvteedaGtYtCvvn 71 ++v++++ atL C + g+p p++tW+++gk+ ++ ++ + + +g+ + +++ +++ + d+G Y C+++ FUN_000407-T6 37 TYVRKSKPATLKCQVG-GNPLPSITWKRNGKQVTLDSRrTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGS 105 789999**********.*********************64444455555589999999*********997 PP == domain 2 score: 28.6 bits; conditional E-value: 2.2e-09 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 t+ v G++a+L C++++++p + v W+k+g+ ++ + ++ + + l+i+n ++e G Y C ++n+ FUN_000407-T6 133 TLSVTFGDTARLFCNVKHSNPKAKVGWRKQGSNVSITTG--DRFTLIPNGALQINNLRFEEQGKYECFATNEI 203 67899*************************998777766..778888888*******************9975 PP == domain 3 score: 25.1 bits; conditional E-value: 2.7e-08 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++++L C as g p p++tW k+g ++ ++ ++ +q +l i +v ++aGtYtC+++ + FUN_000407-T6 242 ESTVVLECVAS-GYPKPSITWLKDGFEISPGQN---GYSILGQGNLMIKSVAVSHAGTYTCRASQT 303 689********.*************99999988...88888999******************9865 PP == domain 4 score: 22.6 bits; conditional E-value: 1.6e-07 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 +++ +++++ C a+ g p p+++Ws +g ++ +s + r+ + l +++ ++d G Y C + ++g++++ FUN_000407-T6 330 AYRNSRVRFECQAE-GIPKPNISWSLNGRELSLSYT------RVVDGVLEVRDLVFSDKGVYQCFAKGHSGKVQA 397 678899********.***************999955......*************************99999887 PP == domain 5 score: -1.9 bits; conditional E-value: 7.1 ig 21 spgpdvtWskegktkies 38 ++ + vtW++ ++ + + FUN_000407-T6 552 ESSIRVTWEVPDTGPVSR 569 667778888877766554 PP >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.0 0.1 4.2e-16 3.7e-13 2 83 .. 443 530 .. 442 531 .. 0.87 2 ! 50.8 0.4 2.4e-16 2.1e-13 2 77 .. 541 617 .. 540 624 .. 0.88 Alignments for each domain: == domain 1 score: 50.0 bits; conditional E-value: 4.2e-16 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+n+ ++ ++t+++++W+pp ++g+i +Y y ++++ v+g++ ++++L+p+teY+++V a n++G g se+++v FUN_000407-T6 443 KPENVVAQVLSDTEIELTWSPPgIPRGKILEYVCIYVKAGGsnvdtvIVSGDTlV--KQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTV 530 7******99999***********99*************88886665555555332..568**************************9987 PP == domain 2 score: 50.8 bits; conditional E-value: 2.4e-16 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne...tvpgsr.etsvtltgLkpgteYevrVqavngaGegee 77 +P++l +++vt++s++v+W+ pd gp+++Y + y+++++ ++++++ +++ l++Lk +t+Y+++V+a ++G ++ FUN_000407-T6 541 KPRDLVAEAVTESSIRVTWEVPD-TGPVSRYVILYKDTSSnerELQDNTkKQTRVLRDLKTYTKYTITVYAEDKDG--MR 617 7*********************5.9************76677****9998777889***************98875..44 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 5.8e-06 0.0051 15 72 .. 43 97 .. 30 105 .. 0.75 2 ! 8.7 0.0 0.0029 2.5 14 45 .. 139 169 .. 127 194 .. 0.77 3 ! 20.4 0.0 6.3e-07 0.00055 5 41 .. 234 268 .. 231 307 .. 0.81 4 ! 15.6 0.0 2e-05 0.018 10 44 .. 328 362 .. 319 370 .. 0.77 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 5.8e-06 C2-set_2 15 kevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredn 72 k +++C gg+P p+itW ++gk++ + ++++++p+ l+ + + ++ ++++ d FUN_000407-T6 43 KPATLKC-QVGGNPLPSITWKRNGKQV-TLDSRRTIKPDGSLYFT-EIFHNRTHKPDE 97 5678899.679***************9.77777777777777766.788888777665 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0029 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaae 45 + + + C ++ ++P++++ W ++g ++ ++ FUN_000407-T6 139 GDTARLFCNVKHSNPKAKVGWRKQGSNV-SIT 169 4567778******************998.333 PP == domain 3 score: 20.4 bits; conditional E-value: 6.3e-07 C2-set_2 5 psaslleaeekevvatCvsaggkPapritWlldgkel 41 p++++ ++e +vv++C +a+g+P+p+itWl+dg e+ FUN_000407-T6 234 PKDTMATTE-STVVLEC-VASGYPKPSITWLKDGFEI 268 455555565.99*****.899************9776 PP == domain 4 score: 15.6 bits; conditional E-value: 2e-05 C2-set_2 10 leae.ekevvatCvsaggkPapritWlldgkeleaa 44 + a + +v ++C a+g P+p+i+W l+g+el+ + FUN_000407-T6 328 VHAYrNSRVRFEC-QAEGIPKPNISWSLNGRELSLS 362 4444678999***.999***************9443 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.3 0.0034 3 59 108 .. 71 120 .. 32 121 .. 0.64 2 ! 15.7 0.1 2.1e-05 0.019 3 99 .. 131 209 .. 129 219 .. 0.72 3 ! 17.8 0.2 4.6e-06 0.004 59 108 .. 272 315 .. 232 316 .. 0.78 4 ? 0.1 0.0 1.4 1.2e+03 2 36 .. 324 355 .. 323 363 .. 0.85 5 ! 9.6 0.0 0.0016 1.4 69 104 .. 365 399 .. 355 404 .. 0.73 6 ? 1.2 0.0 0.66 5.8e+02 25 61 .. 551 587 .. 505 608 .. 0.79 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0034 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + r +++ d s +++ + + D+G+Y+C+ +++ +++ r+tV FUN_000407-T6 71 DSRRTIKPDGSLYFTEIFHNRTHKPDEGIYQCEGSQSYYKIISRTARVTV 120 3333333334555555666678889********65555555999999988 PP == domain 2 score: 15.7 bits; conditional E-value: 2.1e-05 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekk.kgrfslrkdpsrsdfsltiqnltlsDsGtYtCav...ip 94 p++++v G +++L C ++ s ++ +v W +q ++ ++++ ++rf+l ++ l+i+nl+ + +G Y+C + i+ FUN_000407-T6 131 PKTLSVTFGDTARLFCNVKHS--NPKAKVGWRKQGSN---------------VSITtGDRFTLIP-----NGALQINNLRFEEQGKYECFAtneIA 204 778888888888888877755..78888888887754...............3444499******.....*******************9533333 PP V-set 95 kgevv 99 ++++ FUN_000407-T6 205 RKTHT 209 33333 PP == domain 3 score: 17.8 bits; conditional E-value: 4.6e-06 V-set 59 kgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 ++ +s+ + + l i+++ +s++GtYtC+ ++ + +f ++ +L V FUN_000407-T6 272 QNGYSILG-----QGNLMIKSVAVSHAGTYTCR-ASQTTRSFDATAKLDV 315 55666666.....99******************.8999999999998877 PP == domain 4 score: 0.1 bits; conditional E-value: 1.4 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrq 36 +p+ v++ ++ +v++ C+ + ++W+ FUN_000407-T6 324 KPSDVHAYRNSRVRFECQAEGI---PKPNISWSLN 355 68999************98887...9999999865 PP == domain 5 score: 9.6 bits; conditional E-value: 0.0016 V-set 69 srsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 + d+ l++++l sD G+Y+C + + +++ +++ FUN_000407-T6 365 RVVDGVLEVRDLVFSDKGVYQCFA-KGHSGKVQASG 399 566999****************94.44444444444 PP == domain 6 score: 1.2 bits; conditional E-value: 0.66 V-set 25 seasqsvyWyrqppgkepteliayysnkseeekkkgr 61 +e s +v+W ++g ++++i+y ++s+e ++ FUN_000407-T6 551 TESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDN 587 4578899999999998888888888875555444444 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 4e-09 3.5e-06 4 47 .. 25 70 .. 22 88 .. 0.83 2 ? 0.2 0.0 1.4 1.3e+03 9 30 .. 230 251 .. 224 255 .. 0.90 3 ! 7.2 0.0 0.0099 8.8 7 31 .. 319 343 .. 314 368 .. 0.86 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 4e-09 Unc5_NetrinR_N 4 eelPifleePedayivknkpvtLkCka..akalqiyFkCngewvee 47 ++lP+f+eeP+d+y+ k+kp+tLkC++ + i +k ng++v+ FUN_000407-T6 25 ADLPHFIEEPSDTYVRKSKPATLKCQVggNPLPSITWKRNGKQVTL 70 579**********************983346678888888888765 PP == domain 2 score: 0.2 bits; conditional E-value: 1.4 Unc5_NetrinR_N 9 fleePedayivknkpvtLkCka 30 f P+d+ + v+L+C a FUN_000407-T6 230 FQARPKDTMATTESTVVLECVA 251 8899****************88 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0099 Unc5_NetrinR_N 7 PifleePedayivknkpvtLkCkaa 31 P+f ++P+d++ +n v ++C+a+ FUN_000407-T6 319 PVFTKKPSDVHAYRNSRVRFECQAE 343 9**********************96 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0031 2.7 15 57 .. 43 83 .. 36 102 .. 0.74 2 ! 8.1 0.0 0.004 3.5 15 82 .. 140 204 .. 133 209 .. 0.79 3 ! 7.8 0.0 0.0052 4.5 13 37 .. 241 264 .. 235 304 .. 0.71 4 ! 9.2 0.0 0.0019 1.7 9 42 .. 328 359 .. 324 385 .. 0.80 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0031 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglf 57 + +l+C++ G++P P++ W+ + +++ + ++++d+ l+ FUN_000407-T6 43 KPATLKCQV-GGNPLPSITWKRNGKQVTLDSRRTIKPDG-SLY 83 566899996.779*******9987776666666666664.344 PP == domain 2 score: 8.1 bits; conditional E-value: 0.004 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpll 82 + rl C+++ +P+ +v Wr++ ++ ++ ++ +g ++++ r + +++++C+ +n++ FUN_000407-T6 140 DTARLFCNVKHSNPKAKVGWRKQGSNVSITTGDRFTLIPNGALQINNL---RFEEQGKYECFATNEIA 204 56799****************987777667777778888888888764...44667888888888776 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0052 C2-set_3 13 edggirlvCrsaGWyPePqvqWrde 37 + + l+C ++G yP+P++ W + FUN_000407-T6 241 TESTVVLECVASG-YPKPSITWLKD 264 567899***9998.********754 PP == domain 4 score: 9.2 bits; conditional E-value: 0.0019 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekgekl 42 v+ y++ +r +C+++G P+P+++W + g++l FUN_000407-T6 328 VHAYRNSRVRFECQAEG-IPKPNISWSLN-GREL 359 678999*********99.7*******754.4444 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.2 0.013 11 5 51 .. 46 106 .. 42 118 .. 0.65 2 ? 2.9 0.0 0.26 2.3e+02 31 52 .. 181 202 .. 139 213 .. 0.63 3 ! 13.4 0.0 0.00014 0.12 2 54 .. 243 305 .. 242 317 .. 0.77 4 ? 5.7 0.0 0.036 32 4 62 .. 336 405 .. 333 406 .. 0.69 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.013 Ig_4 5 lLtCnsss...keitwlkdgkeikeskek...........tldlgksiedprglYqCkeee 51 +L+C+ +itw+++gk+ + +++ ++ +++ + ++g+YqC++++ FUN_000407-T6 46 TLKCQVGGnplPSITWKRNGKQVTLDSRRtikpdgslyftEIFHNRTHKPDEGIYQCEGSQ 106 67885443124579999999999888877566666444422333344457899****9743 PP == domain 2 score: 2.9 bits; conditional E-value: 0.26 Ig_4 31 tldlgksiedprglYqCkeeek 52 l++++ +++g Y+C +++ FUN_000407-T6 181 ALQINNLRFEEQGKYECFATNE 202 778888888********94333 PP == domain 3 score: 13.4 bits; conditional E-value: 0.00014 Ig_4 2 dkVlLtCnsss...keitwlkdgkeikeskek.......tldlgksiedprglYqCkeeekkk 54 +V+L+C s +itwlkdg ei+ ++ +l ++++ g+Y+C+ +++++ FUN_000407-T6 243 STVVLECVASGypkPSITWLKDGFEISPGQNGysilgqgNLMIKSVAVSHAGTYTCRASQTTR 305 68*****444333368**********9998877788878889999999********9644443 PP == domain 4 score: 5.7 bits; conditional E-value: 0.036 Ig_4 4 VlLtCnsss...keitwlkdgkeikeskek....tldlgksiedprglYqCk....eeekkkssslqvyy 62 V +C+ + +i w +g e + s ++ l++ + + ++g+YqC + + ++s +l vyy FUN_000407-T6 336 VRFECQAEGipkPNISWSLNGRELSLSYTRvvdgVLEVRDLVFSDKGVYQCFakghSGKVQASGQLFVYY 405 555665443322578899999999888888777778888888899******9776533555666677776 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.0 0.0053 4.7 11 33 .. 40 62 .. 30 136 .. 0.75 2 ! 11.8 0.0 0.00028 0.25 12 33 .. 241 262 .. 232 267 .. 0.80 3 ! 11.4 0.0 0.00037 0.33 9 33 .. 329 353 .. 322 357 .. 0.79 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0053 Ig_PDGFR_d4 11 assgeqtvtCvaeGmPqPeveWf 33 +s+ t++C G P P+++W FUN_000407-T6 40 RKSKPATLKCQVGGNPLPSITWK 62 56777899**************6 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00028 Ig_PDGFR_d4 12 ssgeqtvtCvaeGmPqPeveWf 33 +++ ++ Cva G+P+P+++W+ FUN_000407-T6 241 TESTVVLECVASGYPKPSITWL 262 44555678*************7 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00037 Ig_PDGFR_d4 9 shassgeqtvtCvaeGmPqPeveWf 33 + +++ C aeG+P+P+++W FUN_000407-T6 329 HAYRNSRVRFECQAEGIPKPNISWS 353 34456677789*************7 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 0.00024 0.21 46 85 .. 497 536 .. 466 540 .. 0.70 2 ! 20.0 0.0 1e-06 0.00089 19 84 .. 566 630 .. 554 632 .] 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00024 FN3_DSCAM-DSCAML_C 46 klviedLkpatwYelkvtAhneaGsteaeyefaTltltGa 85 ++dL+p t Y++ v A+n+ G+ + e++ t++ + FUN_000407-T6 497 VKQFSDLEPDTEYQFYVFAKNKHGTGAISEEVTVRTYSSS 536 44579*****************999877666666666555 PP == domain 2 score: 20.0 bits; conditional E-value: 1e-06 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTltltG 84 p++ +v+ y+ ++++e l +n+ ++++ v++dLk t+Y+++v A+ + G+ a +t+ G FUN_000407-T6 566 PVSRYVILYKDTSSNERELQDNT-KKQTRVLRDLKTYTKYTITVYAEDKDGMRGAPAVTEATTNGG 630 899*********99998887665.5666799********************988876666555555 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00094 0.83 12 61 .. 41 86 .. 30 106 .. 0.66 2 ? 5.7 0.0 0.031 27 4 43 .. 130 168 .. 127 202 .. 0.75 3 ! 9.5 0.0 0.0019 1.7 5 46 .. 234 273 .. 230 304 .. 0.72 4 ? -0.4 0.0 2.4 2.1e+03 13 43 .. 333 361 .. 320 368 .. 0.66 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00094 C1-set 12 kgkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqll 61 k+k++tL C v g p ++tW++ng++vt ++ +k ++s y++ FUN_000407-T6 41 KSKPATLKCQVGGN--PLPSITWKRNGKQVTL--DSRRTIKPDGSLYFTE 86 3899*******984..344789*********6..6666666666666654 PP == domain 2 score: 5.7 bits; conditional E-value: 0.031 C1-set 4 lppspeelkgkkntLvClvtgfyPpdikVtWlkngqevte 43 +p++ + + g+++ L C v+ P + kV W k+g++v+ FUN_000407-T6 130 VPKTLSVTFGDTARLFCNVKHSNP-KAKVGWRKQGSNVSI 168 555555555999*******98777.89********99985 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0019 C1-set 5 ppspeelkgkkntLvClvtgfyPpdikVtWlkngqevtegvk 46 p+++ +++++++L C+++g+ p ++tWlk+g e++ g + FUN_000407-T6 234 PKDTMATTESTVVLECVASGYPKP--SITWLKDGFEISPGQN 273 5555666799**********9666..679*****99998644 PP == domain 4 score: -0.4 bits; conditional E-value: 2.4 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevte 43 ++ + C ++g+ p +++W ng+e++ FUN_000407-T6 333 NSRVRFECQAEGIPKP--NISWSLNGRELSL 361 5556666777776444..678999*999875 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 7.6e-05 0.067 1 93 [] 444 532 .. 444 532 .. 0.72 2 ! 11.6 0.6 0.00053 0.46 10 82 .. 549 612 .. 542 627 .. 0.63 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 7.6e-05 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgdens....gwsevys 90 Pe+v +++ + +t++ ++W +p + +++++y + + + t+ sg + ++++Lep+t+Y++ v ++n+ + se+ + FUN_000407-T6 444 PENVVAQVLS-DTEIELTWSPPGIPRGKILEYVCIYVKAGGSNVDTV-------IVSGDTLVKQFSDLEPDTEYQFYVFAKNKhgtgAISEEVT 529 6777777777.888888888887667777777776644333222222.......24677888899*************9998778888888888 PP Pur_ac_phosph_N 91 ftT 93 ++T FUN_000407-T6 530 VRT 532 887 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00053 Pur_ac_phosph_N 10 g.pstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvgden 82 + +++s++v+W p++ +pv +y ++++ss+ e ++++ + +l++L+ t+Y +v +e+ FUN_000407-T6 549 AvTESSIRVTWEVPDT--GPVSRYVILYKDTSSNER--------ELQDNTKKQTRVLRDLKTYTKYTITVYAED 612 55789*********86..455555555544333221........112344555667888888888888887664 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.3 2.7e+02 20 42 .. 40 62 .. 32 83 .. 0.84 2 ? -2.1 0.0 6.5 5.7e+03 104 119 .. 192 207 .. 187 211 .. 0.86 3 ? 4.6 0.0 0.057 50 26 45 .. 246 265 .. 231 288 .. 0.85 4 ! 9.0 0.0 0.0025 2.2 20 47 .. 332 358 .. 312 372 .. 0.79 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.3 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwf 42 r + l c g p+p itw FUN_000407-T6 40 RKSKPATLKCQVGGNPLPSITWK 62 555566799*************6 PP == domain 2 score: -2.1 bits; conditional E-value: 6.5 Ig_VEGFR-1-like_5th 104 sgvysctarnelgnrt 119 g y c a ne+ +t FUN_000407-T6 192 QGKYECFATNEIARKT 207 589********99887 PP == domain 3 score: 4.6 bits; conditional E-value: 0.057 Ig_VEGFR-1-like_5th 26 kltctafgipmpnitwfwqp 45 l c a g p p itw+ + FUN_000407-T6 246 VLECVASGYPKPSITWLKDG 265 589*************9765 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0025 Ig_VEGFR-1-like_5th 20 rydqrhkltctafgipmpnitwfwqpcd 47 r + r ++ c a gip pni+w + + FUN_000407-T6 332 R-NSRVRFECQAEGIPKPNISWSLNGRE 358 3.568999**************876655 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 2.3 2.1e+03 49 88 .. 59 106 .. 46 120 .. 0.60 2 ? 4.3 0.1 0.052 46 28 93 .. 140 206 .. 116 217 .. 0.74 3 ! 10.1 0.0 0.00084 0.74 27 101 .. 242 315 .. 227 326 .. 0.67 4 ? -0.5 0.0 1.7 1.5e+03 27 61 .. 333 362 .. 320 401 .. 0.67 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2.3 V-set_CD47 49 vkWkfnnkdifisnktekkst..........LkldfsdalsGnYtCevte 88 + Wk+n+k+++ + + ++ +G Y Ce ++ FUN_000407-T6 59 ITWKRNGKQVTLDSRRTI--KpdgslyfteiFHNRTHKPDEGIYQCEGSQ 106 788888888776544422..233554544422222233346777777655 PP == domain 2 score: 4.3 bits; conditional E-value: 0.052 V-set_CD47 28 dtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst....Lkldfsd.alsGnYtCevtelsnev 93 dt + C+v++ + ++ v W+ +++++ i + + + + L++++ + +G Y C +t++ + FUN_000407-T6 140 DTARLFCNVKH----SNPKAKVGWRKQGSNVSITTGDRFTLIpngaLQINNLRfEEQGKYECFATNEIARK 206 66778899966....446788******999999988855555888866665441458*****999876543 PP == domain 3 score: 10.1 bits; conditional E-value: 0.00084 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkst.....Lkld.fsdalsGnYtCevtelsnevkttieLkl 101 +tvv+eC + ++ + W ++ +i ++ s+ L ++ + +G+YtC +++++++ t +L + FUN_000407-T6 242 ESTVVLECVASGYPKP-----SITWLKDGFEISPGQNGY--SIlgqgnLMIKsVAVSHAGTYTCRASQTTRSFDATAKLDV 315 5777777777664444.....457777777766544432..222355544441455679***************9999987 PP == domain 4 score: -0.5 bits; conditional E-value: 1.7 V-set_CD47 27 ndtvvieCdvdnleyknisevyvkWkfnnkdifis 61 n+ v eC+ + +++ n ++W++n++++ s FUN_000407-T6 333 NSRVRFECQAEGIPKPN-----ISWSLNGRELSLS 362 67777778776666555.....5999999887655 PP >> DUF4998 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.2 1.9e-06 0.0017 82 188 .. 505 608 .. 456 613 .. 0.88 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 1.9e-06 DUF4998 82 eEgsytfeivtydkkgnsSvavevsaevYGdsYqssLtnrslksaelekkeltikwskvekeaklvkteleYtnkagetktvrikkkeeqtkltdf 177 + y+f +++++k+g ++ ev+ +Y +s + r l++ +++++++ ++w+ + + + + Y++++ ++++++ + k+++ +l d FUN_000407-T6 505 PDTEYQFYVFAKNKHGTGAISEEVTVRTYSSSAVPG-KPRDLVAEAVTESSIRVTWEVPDTGP-VSRYVILYKDTSSNERELQDNTKKQTRVLRDL 598 5678*************************8875554.89*******************99999.99****************************** PP DUF4998 178 kpgtsfkyrtv 188 k t++++ tv FUN_000407-T6 599 KTYTKYTI-TV 608 *9999987.44 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.22 1.9e+02 42 85 .. 472 516 .. 453 531 .. 0.80 2 ! 13.7 0.1 9.2e-05 0.081 43 88 .. 569 613 .. 551 624 .. 0.84 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.22 Interfer-bind 42 lqYkvsywknssnkekkelestnelv.vlsdLepnteYCvsVqae 85 l+Y +y k + ++ ++++ s +lv +sdLep teY + V a+ FUN_000407-T6 472 LEYVCIYVKAGGSNVDTVIVSGDTLVkQFSDLEPDTEYQFYVFAK 516 67888888888776777776666655169*********9888773 PP == domain 2 score: 13.7 bits; conditional E-value: 9.2e-05 Interfer-bind 43 qYkvsywknssnkekkelestnelvvlsdLepnteYCvsVqaesrk 88 Y + y +ssn+++ + ++++++ vl+dL+ t+Y ++V+a ++k FUN_000407-T6 569 RYVILYKDTSSNERELQDNTKKQTRVLRDLKTYTKYTITVYA-EDK 613 699*********7777777777778*****************.444 PP >> Shr-like_HID Heme-binding protein Shr-like, Hb-interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.029 25 23 64 .. 158 196 .. 136 197 .. 0.87 2 ? 5.3 0.0 0.043 38 34 64 .. 264 297 .. 236 301 .. 0.84 3 ? 1.1 0.0 0.92 8.1e+02 32 63 .. 353 384 .. 347 386 .. 0.86 4 ? -1.7 0.0 6.8 6e+03 61 70 .. 602 611 .. 596 629 .. 0.77 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.029 Shr-like_HID 23 aWrsaitevkvnGtelssdkYti.eagkitldagvftkageyt 64 Wr++ ++v++ t+ +d++t+ +g +++++ f+++g+y+ FUN_000407-T6 158 GWRKQGSNVSI--TT--GDRFTLiPNGALQINNLRFEEQGKYE 196 69999999999..44..777**9988**************996 PP == domain 2 score: 5.3 bits; conditional E-value: 0.043 Shr-like_HID 34 nGtelssdk..Yti.eagkitldagvftkageyt 64 +G e+s+++ Y+i +g++ +++ + ++ag+yt FUN_000407-T6 264 DGFEISPGQngYSIlGQGNLMIKSVAVSHAGTYT 297 67777755556****88****************8 PP == domain 3 score: 1.1 bits; conditional E-value: 0.92 Shr-like_HID 32 kvnGtelssdkYti.eagkitldagvftkagey 63 ++nG els + Yt +g +++ + vf+ +g y FUN_000407-T6 353 SLNGRELSLS-YTRvVDGVLEVRDLVFSDKGVY 384 579***9999.887789**********999988 PP == domain 4 score: -1.7 bits; conditional E-value: 6.8 Shr-like_HID 61 geytitikAt 70 +ytit+ A+ FUN_000407-T6 602 TKYTITVYAE 611 5688888776 PP >> Sp38 Zona-pellucida-binding protein (Sp38) N-terminal Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.4 1.3e+03 32 79 .. 59 113 .. 56 121 .. 0.64 2 ? 1.6 0.0 0.44 3.9e+02 43 79 .. 169 205 .. 153 218 .. 0.73 3 ! 10.3 0.0 0.00084 0.74 30 82 .. 257 309 .. 245 321 .. 0.82 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.4 Sp38 32 ylWiGPdgkllsgnssinitetGelvlkd.f....eeslsGvytctls...ykivk 79 +W+ +gk+++ +s+ i + G+l +++ f +++ G+y c s yki++ FUN_000407-T6 59 ITWK-RNGKQVTLDSRRTIKPDGSLYFTEiFhnrtHKPDEGIYQCEGSqsyYKIIS 113 5665.478999999999999999998876231111234468888864322255554 PP == domain 2 score: 1.6 bits; conditional E-value: 0.44 Sp38 43 sgnssinitetGelvlkdfeeslsGvytctlsykivk 79 + ++ + + G l +++++ + G y c+ + i + FUN_000407-T6 169 TTGDRFTLIPNGALQINNLRFEEQGKYECFATNEIAR 205 44456778899*********9********98766544 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00084 Sp38 30 PvylWiGPdgkllsgnssinitetGelvlkdfeeslsGvytctlsykivkaea 82 P+ +W +++ g++ i + G+l++k s +G+ytc s + + +a FUN_000407-T6 257 PSITWLKDGFEISPGQNGYSILGQGNLMIKSVAVSHAGTYTCRASQTTRSFDA 309 666777777778889999999*********************98876655555 PP >> NDNF Neuron-derived neurotrophic factor, first Fn(III) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.0 0.00094 0.82 83 113 .. 490 520 .. 425 533 .. 0.85 2 ? 4.5 0.0 0.053 47 85 111 .. 587 613 .. 542 627 .. 0.75 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00094 NDNF 83 vCvgkktvqtvseLkpdtqYyfdvFavdqkr 113 + g++ v +s+L+pdt+Y f vFa +++ FUN_000407-T6 490 IVSGDTLVKQFSDLEPDTEYQFYVFAKNKHG 520 44577778889***************99875 PP == domain 2 score: 4.5 bits; conditional E-value: 0.053 NDNF 85 vgkktvqtvseLkpdtqYyfdvFavdq 111 kk+ ++++Lk t+Y ++v+a d+ FUN_000407-T6 587 NTKKQTRVLRDLKTYTKYTITVYAEDK 613 556777889**************9876 PP >> InlK_D3 Internalin K domain (D3/D4) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.41 3.6e+02 45 74 .. 502 531 .. 492 532 .. 0.87 2 ! 12.5 0.1 0.00019 0.17 45 68 .. 597 620 .. 578 624 .. 0.88 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.41 InlK_D3 45 dlntpGdYtVtLnAededgnkaepveVtVt 74 dl+ +Y+ + A++++g+ a + eVtV+ FUN_000407-T6 502 DLEPDTEYQFYVFAKNKHGTGAISEEVTVR 531 56667799999****************995 PP == domain 2 score: 12.5 bits; conditional E-value: 0.00019 InlK_D3 45 dlntpGdYtVtLnAededgnkaep 68 dl+t +Yt+t++Aed+dg+ +p FUN_000407-T6 597 DLKTYTKYTITVYAEDKDGMRGAP 620 899*****************9988 PP >> GH101_dom-5 Endo-alpha-N-acetylgalactosaminidase, domain 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.031 28 45 69 .. 495 519 .. 476 537 .. 0.77 2 ? 7.6 0.2 0.0049 4.4 17 69 .. 564 614 .. 551 628 .. 0.77 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.031 GH101_dom-5 45 svsqkltdLkpgkkYavyvgvdnrs 69 ++ ++ +dL+p ++Y yv n+ FUN_000407-T6 495 TLVKQFSDLEPDTEYQFYVFAKNKH 519 566889*************999974 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0049 GH101_dom-5 17 sgdgekaevvksqgsnpmlklsgekedvsvsqkltdLkpgkkYavyvgvdnrs 69 +g +++ + +++s + +l++ ++ + ++ l dLk +kY + v+ +++ FUN_000407-T6 564 TGPVSRYVILYKDTSSNERELQD--NTKKQTRVLRDLKTYTKYTITVYAEDKD 614 66777777888888888889999..55667899***************99875 PP >> Cadherin Cadherin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.38 3.3e+02 40 92 .. 166 218 .. 146 219 .. 0.69 2 ? 3.7 0.0 0.13 1.1e+02 60 89 .. 502 531 .. 495 532 .. 0.89 3 ? 5.0 0.1 0.051 45 58 86 .. 597 623 .. 547 628 .. 0.70 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.38 Cadherin 40 e....ggnFridpetgdisttkpLDrEergeYeLtveatdssgspplsstatvtitV 92 + g+ F++ p +g ++++ +L Ee+g+Ye + at++ + + +st+ +++V FUN_000407-T6 166 VsittGDRFTLIP-NGALQIN-NLRFEEQGKYE--CFATNEIARKTHTSTTVGNVKV 218 4445567788888.7888887.9*********8..6788884455566666556665 PP == domain 2 score: 3.7 bits; conditional E-value: 0.13 Cadherin 60 DrEergeYeLtveatdssgspplsstatvt 89 D E eY+++v a+++ g+ + s+++tv+ FUN_000407-T6 502 DLEPDTEYQFYVFAKNKHGTGAISEEVTVR 531 678899***********9999999999985 PP == domain 3 score: 5.0 bits; conditional E-value: 0.051 Cadherin 58 pLDrEergeYeLtveatdssgspplssta 86 L ++ +Y++tv+a+d++g ++ +++ FUN_000407-T6 597 DLK--TYTKYTITVYAEDKDGMRGAPAVT 623 333..489***********7666555544 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.34 3e+02 43 92 .. 154 199 .. 137 217 .. 0.66 2 ? 9.0 0.0 0.0018 1.6 68 93 .. 276 301 .. 235 313 .. 0.82 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.34 Ig_6 43 ksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 k +V W +q ++ i+ + aL+++ ++ ++ G Y C FUN_000407-T6 154 KAKVGWRKQGSN----VSITTGDRFTLIPNGALQINNLRFEEQGKYECFA 199 556666554433....2334444345567889999999999*****9975 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0018 Ig_6 68 iileknaLrfkpvkvndsGlYiCrpr 93 il + +L +k+v v+++G+Y Cr FUN_000407-T6 276 SILGQGNLMIKSVAVSHAGTYTCRAS 301 5678899****************953 PP >> Ig_J Tip attachment protein J, Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 6.8 6e+03 71 89 .. 501 520 .. 457 531 .. 0.72 2 ? 12.1 0.2 0.00025 0.22 27 97 .. 554 623 .. 531 628 .. 0.73 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 6.8 Ig_J 71 seL.plGkytltvrakneeG 89 s+L p +y+ v akn++G FUN_000407-T6 501 SDLePDTEYQFYVFAKNKHG 520 44423456777777777776 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00025 Ig_J 27 qvrakWdtprvvkgvsFelkltveeddsdrlvsrattsdteyrlseLp.lGkytltvrakneeGqqGeeasv 97 +r++W+ p + ++ + l ++ +s++ +++t+ ++ +l++L+ kyt+tv a +++G +G +a + FUN_000407-T6 554 SIRVTWEVPDTGPVSRY-VILYKD-TSSNERELQDNTKKQTRVLRDLKtYTKYTITVYAEDKDGMRGAPAVT 623 58999999998655555.556554.344455556666777778899962689****************9976 PP >> fn3_4 Fibronectin-III type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 9.8 8.7e+03 37 64 .. 194 218 .. 185 231 .. 0.67 2 ? 2.8 0.0 0.17 1.5e+02 2 24 .. 440 462 .. 439 476 .. 0.93 3 ? -0.6 0.0 2 1.8e+03 72 93 .. 499 520 .. 495 529 .. 0.82 4 ? 5.4 0.0 0.026 23 2 61 .. 538 597 .. 537 619 .. 0.81 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 9.8 fn3_4 37 sYelflyqeetktssstdsWkkigdvkA 64 Ye f+++e +++ + + +g+vk FUN_000407-T6 194 KYECFATNEIARKTHT-S--TTVGNVKV 218 6889999884444433.2..35555555 PP == domain 2 score: 2.8 bits; conditional E-value: 0.17 fn3_4 2 pPqkpelkiakvevptgivlsWn 24 P+kpe +a+v ++t+i l+W FUN_000407-T6 440 FPEKPENVVAQVLSDTEIELTWS 462 69********************6 PP == domain 3 score: -0.6 bits; conditional E-value: 2 fn3_4 72 tlsqfkegkkyyfavrakDiyg 93 ++s++++++ y+f v ak +g FUN_000407-T6 499 QFSDLEPDTEYQFYVFAKNKHG 520 5789999999****99999987 PP == domain 4 score: 5.4 bits; conditional E-value: 0.026 fn3_4 2 pPqkpelkiakvevptgivlsWnvekldpkaaevesYelflyqeetktssstdsWkkigd 61 +P kp+ +a+ ++++i ++W+v+++ p+ v Y+ ++e++ + +++++ + + d FUN_000407-T6 538 VPGKPRDLVAEAVTESSIRVTWEVPDTGPVSRYVILYKDTSSNERELQDNTKKQTRVLRD 597 68899989999999*************999999999987777777776666665555555 PP >> Monellin Monellin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.00022 0.2 7 32 .. 508 533 .. 506 535 .. 0.93 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00022 Monellin 7 diqlyvYasdkLfkadvdEdyKirqr 32 ++q yv+a +k + +++E+ +r + FUN_000407-T6 508 EYQFYVFAKNKHGTGAISEEVTVRTY 533 9*******************999987 PP >> Y_Y_Y Y_Y_Y domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.1 0.015 13 39 57 .. 508 526 .. 508 533 .. 0.81 2 ? 4.1 0.0 0.071 63 39 51 .. 603 615 .. 601 626 .. 0.87 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.015 Y_Y_Y 39 kYtlkVkakdkdgnweydd 57 +Y+++V+ak+k g+ + ++ FUN_000407-T6 508 EYQFYVFAKNKHGTGAISE 526 7***********9988764 PP == domain 2 score: 4.1 bits; conditional E-value: 0.071 Y_Y_Y 39 kYtlkVkakdkdg 51 kYt++V+a dkdg FUN_000407-T6 603 KYTITVYAEDKDG 615 7**********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (632 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 687 (0.0268937); expected 510.9 (0.02) Passed Vit filter: 74 (0.00289685); expected 25.5 (0.001) Passed Fwd filter: 29 (0.00113525); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 29 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6106.68 // Query: FUN_000408-T1 [L=459] Description: FUN_000408 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-32 113.8 0.1 2.6e-32 113.1 0.1 1.3 1 His_Phos_2 Histidine phosphatase superfamily (branch 2) ------ inclusion threshold ------ 0.089 12.9 0.2 0.22 11.6 0.2 1.6 1 TatA_B_E mttA/Hcf106 family Domain annotation for each model (and alignments): >> His_Phos_2 Histidine phosphatase superfamily (branch 2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 113.1 0.1 2.1e-36 2.6e-32 1 353 [. 83 417 .. 83 418 .. 0.82 Alignments for each domain: == domain 1 score: 113.1 bits; conditional E-value: 2.1e-36 His_Phos_2 1 eleqvqvvsRHGdRtPtqkkkkeveslifkllse...................lagslegklsflgtyrk...eklqytlkwggltpaGrkqaeel 74 el vq+ +RHG+RtP + + ++ ++ + g+ +++t++ l+++ ++g+lt G++q+++l FUN_000408-T1 83 ELVLVQIAFRHGARTPIFRSPCQELDD------VtwpaelhvgalphtavdyqMKHVSGGPAPISETNNRllkLLLTGGTPVGHLTKVGQQQTYNL 172 5778************87775333222......1444555789********9999999999999999988988889999999************** PP His_Phos_2 75 GrqfrqrYv...eLlrneltqkdlkirasseeRviaSAeafaeGllgaegvdkdksllddsnvakviideekkalanlllagyescpafes..... 162 G+ +++Yv ++l++ + ++++++r+++ +R+i+SA ++G++g e+ + +i+ + +++++l ++++ c++ ++ FUN_000408-T1 173 GKDCAKNYVeklKFLQETYSPQEIFVRTTNFQRTIDSARCMVAGMFGKEN------------LKGLTIHT-ENEENEILYPNSDYCKNLKNwtkfs 255 *******************99*************************5555............66666666.5689999999*********955555 PP His_Phos_2 163 ..iknakrvdealkklkkdlleniakrlskllpgetnltaddvwslldkcffetnkadlspfcdlfte..edllhneylkdleelyglygignelk 254 + k+ d ++ + +++++ + +++ + + + ++ + +n++ + ++++f+ e++l+ + ++ + g+e+ FUN_000408-T1 256 lsLDGLKKLDGFQNRQEEIYRTLAI-----N--YHEKPNVAVHLRDIVVTMRAHNMKVPKAINQVFNVieEQALQL--FLTMQCGTSH-LSGKEVL 341 5555555555555555555544444.....2..3335555556666666668888889999999999966666666..8888877777.899**** PP His_Phos_2 255 ktiGgpllnellarlendlqaekeatfprdaklylyftHDttiasllsaLglfdelekesklkvldslkasgevpyaarlvfElyecsseed.ryv 349 + g++l ++++ e+++++++ + kl l ++HDtt++ ll aLg+f+ +++++aa + fEly++ ++d ++v FUN_000408-T1 342 SLAVGLFLEHIVENCEKKINNNN------NYKLMLFSSHDTTLVLLLLALGIFN----------------NRWPDFAADVAFELYRD--KDDvYFV 413 ***********************......*************************................79**************5..5555*** PP His_Phos_2 350 rlll 353 r+l+ FUN_000408-T1 414 RVLH 417 *985 PP >> TatA_B_E mttA/Hcf106 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.2 1.7e-05 0.22 15 30 .. 8 23 .. 7 24 .. 0.91 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.7e-05 TatA_B_E 15 aLlvfGPekLPelart 30 a +++GP+kLP l+r+ FUN_000408-T1 8 AAILLGPKKLPVLVRS 23 679**********996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (459 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 691 (0.0270503); expected 510.9 (0.02) Passed bias filter: 556 (0.0217655); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4388.65 // Query: FUN_000409-T1 [L=538] Description: FUN_000409 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-23 83.2 19.5 7.8e-23 81.7 19.5 1.8 1 CD20 CD20-like family 0.0065 16.4 0.3 0.0065 16.4 0.3 1.7 2 FAM70 FAM70 protein Domain annotation for each model (and alignments): >> CD20 CD20-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 81.7 19.5 6.1e-27 7.8e-23 2 157 .] 21 179 .. 20 179 .. 0.96 Alignments for each domain: == domain 1 score: 81.7 bits; conditional E-value: 6.1e-27 CD20 2 LgvvQIllGllslvlGvilasvsssstllksgypfwggivfiisGvlgiiaekrstkllvklslllnllslvtavagiillslslalltsaheqke 97 +gvvQIllG+ +++l++ ++ ++ss +++ +p+w+g+++ sG +g+ia+k+st ++++l+++++++++v+ ++g+ l++ +l+s +++ FUN_000409-T1 21 FGVVQILLGISLTSLSFTAFTFTSS-NRIRNACPYWAGFTVLCSGGVGLIAWKNSTVMSMSLFTFFSAVCVVLQMIGTLLTGDAGGHLKSLLMCEK 115 69***********************.****************************************************************999966 PP CD20 98 eesdl....lsststesskssseeeecraylsslkglltgilavlliltvlellvsllsailgc 157 s+ ++s + ++++s e+e ++ +s l+glltg+++ l++lt++ +++++ +ilgc FUN_000409-T1 116 LVSSEickcCDSVNACQHSSVGIEFEGVSDCSLLTGLLTGLMYGLFVLTIFGSILCFVATILGC 179 555447788*****************************************************99 PP >> FAM70 FAM70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.1 0.79 1e+04 18 48 .. 13 43 .. 7 71 .. 0.52 2 ! 16.4 0.3 5.1e-07 0.0065 147 262 .. 111 229 .. 103 293 .. 0.66 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 0.79 FAM70 18 rrkrtsllvtvsllvvslliltvGlaattrt 48 + ++t+l + v +++++ + + ++a t t FUN_000409-T1 13 KIRQTTLGFGVVQILLGISLTSLSFTAFTFT 43 5555555554444444444444444443333 PP == domain 2 score: 16.4 bits; conditional E-value: 5.1e-07 FAM70 147 ksCklkvksntcyCcdlyncesvelsgayyefvgvssCqdvvhly.rllWastvlnvlglflGiitaavlGafkdmvPasql...aaseaaapkil 238 C+ v s+ c Ccd n ++s+ ef gvs C + l l++ vl + g +l + a +lG + + ++ ++++ + FUN_000409-T1 111 LMCEKLVSSEICKCCDSVN--ACQHSSVGIEFEGVSDCSLLTGLLtGLMYGLFVLTIFGSILCFV-ATILGCTAVARETGRNqglCSRHSSRRSEC 203 579999*********9775..456788899*********9998651699*************876.889997654443322222465555555555 PP FAM70 239 ynpaqqvlsyagfcksa..ealpays 262 ++ +++ ++ ++ + + ++lp+y+ FUN_000409-T1 204 SHDHDDRYTWVSYPTGTdlTMLPPYA 229 55555555555544333113455554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (538 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1195 (0.0467802); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.38u 0.35s 00:00:00.73 Elapsed: 00:00:00.52 # Mc/sec: 4212.33 // Query: FUN_000410-T1 [L=154] Description: FUN_000410 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.99 10.3 10.2 2 9.3 9.9 1.7 1 DUF7571 Family of unknown function (DUF7571) Domain annotation for each model (and alignments): >> DUF7571 Family of unknown function (DUF7571) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 9.9 7.8e-05 2 16 70 .. 49 103 .. 29 117 .. 0.78 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 7.8e-05 DUF7571 16 ldkqleplrdltvddfnvcadcvtvvadacvecgg..avyvprsesetpdycpacrs 70 kq e rdl d ca c + +c +c+ a++vpr++ ++p++ p + FUN_000410-T1 49 ETKQCEKKRDLVSDCALNCAACS--DDGECTKCKKkfALWVPRKQGRSPKCIPCAKV 103 46999******999888898887..57789999754499***********9998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (154 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1483 (0.0580544); expected 510.9 (0.02) Passed bias filter: 353 (0.0138188); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1545.61 // Query: FUN_000411-T1 [L=272] Description: FUN_000411 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 13.6 0.0 0.066 13.0 0.0 1.2 1 Casc1_C Cancer susceptibility candidate 1 C-terminal Domain annotation for each model (and alignments): >> Casc1_C Cancer susceptibility candidate 1 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 2.6e-06 0.066 111 163 .. 46 97 .. 40 110 .. 0.85 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2.6e-06 Casc1_C 111 rkrfvekninifaehdasfyienGyfsvkhlaaelhvydalalhckllkfyrs 163 k kn +f e+ ++ +nG f++k + l +da+++ ck ++f FUN_000411-T1 46 CKEERPKNCSVFNEDGKCIACDNG-FALKEMKWSLACHDAICIPCKYMRFNSQ 97 55566799***************9.79**********************9755 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1212 (0.0474457); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2674.18 // Query: FUN_000412-T1 [L=131] Description: FUN_000412 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-06 28.1 0.0 4.3e-06 27.7 0.0 1.1 1 TMEM128 TMEM128 protein 0.0041 17.1 0.0 0.0046 16.9 0.0 1.0 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.0055 16.7 0.7 0.82 9.8 0.1 2.2 2 DUF3098 Protein of unknown function (DUF3098) ------ inclusion threshold ------ 0.017 15.2 0.0 0.02 14.9 0.0 1.1 1 Nodulin-like Nodulin-like 0.019 15.6 1.4 0.38 11.4 0.2 2.1 2 COX2_TM Cytochrome C oxidase subunit II, transmembra 0.019 16.4 0.4 0.27 12.8 0.0 2.1 2 YxzE YxzE-like putative bacteriocin 0.029 14.9 0.0 0.037 14.5 0.0 1.2 1 MARVEL Membrane-associating domain 0.059 14.1 1.0 0.059 14.1 1.0 2.2 2 YhzF YhzF protein 0.065 13.8 0.0 0.89 10.1 0.0 2.1 2 DUF7555 Family of unknown function (DUF7555) 0.093 12.7 0.1 0.55 10.2 0.0 1.8 2 DUF6377 Domain of unknown function (DUF6377) 0.1 13.6 0.0 1 10.4 0.0 2.0 2 INV_N Beta-fructofuranosidase, N-terminal domain 0.17 12.6 0.5 3.1 8.6 0.5 2.3 1 DUF3040 Protein of unknown function (DUF3040) 0.17 12.6 0.2 0.17 12.6 0.2 1.8 2 YiaAB yiaA/B two helix domain 0.18 12.1 0.3 0.51 10.6 0.1 1.5 1 Claudin_2 PMP-22/EMP/MP20/Claudin tight junction 0.19 11.9 0.1 0.27 11.4 0.1 1.2 1 DUF4131 Domain of unknown function (DUF4131) 0.21 12.0 0.6 0.21 12.0 0.6 2.2 2 LapA_dom Lipopolysaccharide assembly protein A domain 0.35 11.6 3.9 4.9 7.9 3.9 2.1 1 Pox_A14 Poxvirus virion envelope protein A14 0.36 11.7 1.7 0.49 11.3 0.9 1.7 2 FeoB_associated FeoB-associated Cys-rich membrane protein 0.73 9.7 2.3 6.3 6.6 0.2 2.1 2 Sema4F_C Semaphorin 4F C-terminal 0.8 10.2 2.2 1.4 9.4 0.0 2.2 2 DUF5408 Family of unknown function (DUF5408) 6.8 7.3 6.3 0.59 10.7 0.5 1.9 2 Herpes_UL73 UL73 viral envelope glycoprotein Domain annotation for each model (and alignments): >> TMEM128 TMEM128 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 3.6e-09 4.3e-06 35 100 .. 20 88 .. 4 91 .. 0.82 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 3.6e-09 TMEM128 35 in.rlwlylgllllgvnlliflylavylpyi..kkvsyenwektapraipiatvlgvvsfilfiialWp 100 i+ +++ +g++l++v+++++ + + y ++ +y + +k+a ++ +a+++++++fil++i+lW+ FUN_000412-T1 20 IRdAILIFIGIILITVCFVLLGVAQSYDKKDtrGDCDYCDSKKHANAFRVFASICFLLGFILMTISLWH 88 3336777889999999999999999998887666678888899999999*******************8 PP >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 3.8e-06 0.0046 99 194 .. 16 109 .. 5 126 .. 0.65 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 3.8e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 99 krralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkkks 194 +r+ + +++++ +l+++ ++l+ ++++++ ++ C+ + +++ ++ ++++ ++++lgf+l + i+ + r l++++ ++++ ++++ + FUN_000412-T1 16 RRKIIRDAILIFIGIILITVCFVLLGVAQSYDKKDTRGDCDYCDSKKHANAFRVFASICFLLGFIL--MTISLWHLRSLKRAQGQNRRLMEQQRLM 109 45555556667776677777766666666666669999**99999965556666666666666664..5556666677777777766666555544 PP >> DUF3098 Protein of unknown function (DUF3098) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.1 0.00068 0.82 8 32 .. 24 48 .. 20 52 .. 0.85 2 ? 5.4 0.1 0.016 19 13 25 .. 71 83 .. 61 86 .. 0.79 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00068 DUF3098 8 illliglaviilGfiLMsGggsddp 32 il++ig+++i++ f+L+ +s d+ FUN_000412-T1 24 ILIFIGIILITVCFVLLGVAQSYDK 48 89**************987777765 PP == domain 2 score: 5.4 bits; conditional E-value: 0.016 DUF3098 13 glaviilGfiLMs 25 + ++ +lGfiLM+ FUN_000412-T1 71 ASICFLLGFILMT 83 6778899999996 PP >> Nodulin-like Nodulin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 1.7e-05 0.02 160 219 .. 22 86 .. 14 97 .. 0.89 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 1.7e-05 Nodulin-like 160 ksllllvalvplvvslvvlylvrevekl.....pkkkeersesavFlvllvisvllavyllvvsi 219 + +l++++++ + v++v+l + + +k+ +++ +++ +++F v+ i++ll++ l+++s+ FUN_000412-T1 22 DAILIFIGIILITVCFVLLGVAQSYDKKdtrgdCDYCDSKKHANAFRVFASICFLLGFILMTISL 86 56899*****************9999888888899999999********************9985 PP >> COX2_TM Cytochrome C oxidase subunit II, transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.2 0.00031 0.38 22 52 .. 20 50 .. 14 61 .. 0.88 2 ? 3.4 0.1 0.098 1.2e+02 23 54 .. 63 95 .. 58 109 .. 0.64 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00031 COX2_TM 22 lhdyilliltlililVlyilvlllvefnrkk 52 + d il+++ +ili+V+++l+ + ++ +k FUN_000412-T1 20 IRDAILIFIGIILITVCFVLLGVAQSYDKKD 50 7899*****************9999987765 PP == domain 2 score: 3.4 bits; conditional E-value: 0.098 COX2_TM 23 hdyilliltlililVlyilvll.lvefnrkknk 54 h +++ + + i++l +il+++ l++ ++ k + FUN_000412-T1 63 HANAFRVFASICFLLGFILMTIsLWHLRSLKRA 95 567777888899999888877624555444433 PP >> YxzE YxzE-like putative bacteriocin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.00022 0.27 3 36 .. 25 59 .. 23 68 .. 0.82 2 ? 2.2 0.1 0.45 5.5e+02 8 29 .. 72 93 .. 65 122 .. 0.49 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00022 YxzE 3 livllilvfiliiiilavltsskskkkkkrssy.d 36 li+++i+++ ++++l v++s ++k ++ + +y d FUN_000412-T1 25 LIFIGIILITVCFVLLGVAQSYDKKDTRGDCDYcD 59 79999*****************9999988877755 PP == domain 2 score: 2.2 bits; conditional E-value: 0.45 YxzE 8 ilvfiliiiilavltsskskkk 29 + f+l +i+++++ + ++ k FUN_000412-T1 72 SICFLLGFILMTISLWHLRSLK 93 3445555554444433333322 PP >> MARVEL Membrane-associating domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 3.1e-05 0.037 73 134 .] 20 81 .. 2 93 .. 0.61 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.1e-05 MARVEL 73 lvdlildalaalfwlaafialaaalrdinqgskdltrrcsaakAaiaFgflafllflasavl 134 + d il ++ ++ ++f++l +a++ + +++ c++ k a aF +a ++fl+ ++l FUN_000412-T1 20 IRDAILIFIGIILITVCFVLLGVAQSYDKKDTRGDCDYCDSKKHANAFRVFASICFLLGFIL 81 44556666666666666666666666633333344555566666666666666666555543 PP >> YhzF YhzF protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 1.4 0.38 4.6e+02 6 16 .. 30 40 .. 22 46 .. 0.50 2 ? 14.1 1.0 4.9e-05 0.059 3 29 .. 69 95 .. 67 96 .. 0.93 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.38 YhzF 6 filfiiSflll 16 +il++++f+ll FUN_000412-T1 30 IILITVCFVLL 40 34444444444 PP == domain 2 score: 14.1 bits; conditional E-value: 4.9e-05 YhzF 3 giifilfiiSfllllgmiyyllalkrp 29 ++++i+f+++f+l +++++l++lkr+ FUN_000412-T1 69 VFASICFLLGFILMTISLWHLRSLKRA 95 6899*********************97 PP >> DUF7555 Family of unknown function (DUF7555) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.29 3.5e+02 43 73 .. 24 54 .. 16 73 .. 0.73 2 ? 10.1 0.0 0.00073 0.89 44 85 .. 74 116 .. 67 128 .. 0.69 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.29 DUF7555 43 lLFvvGfllfgygtlrlrPkspwkedkeees 73 +L ++G++l+ + + l ++++++++++ + FUN_000412-T1 24 ILIFIGIILITVCFVLLGVAQSYDKKDTRGD 54 5778999999999999998888888776544 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00073 DUF7555 44 LFvvGfllfgygtlrlrPkspwkedkeeesee.stvesreetr 85 F++Gf+l+ ++++ lr+ + + ++++ +e+ + +++ee++ FUN_000412-T1 74 CFLLGFILMTISLWHLRSLKRAQGQNRRLMEQqRLMGNHEESE 116 6****************86655555544443335555555544 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.4 4.9e+02 74 92 .. 25 40 .. 5 53 .. 0.50 2 ? 10.2 0.0 0.00045 0.55 67 132 .. 61 122 .. 54 129 .. 0.69 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.4 DUF6377 74 lillilisvllllllvllv 92 li++ ++l++++++l+ FUN_000412-T1 25 LIFI---GIILITVCFVLL 40 2222...222222222222 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00045 DUF6377 67 ekqkrkllillilisvllllllvllviiykqlkklkkarkelkeaneqlkelneeneqnekLsean 132 +k + +++++ ++++l +l+ + ++ ++ lk+ + ++++l e+++ + ++ ee e +++ n FUN_000412-T1 61 KKHANAFRVFASICFLLGFILMTISLWHLRSLKRAQGQNRRLMEQQRLMGNH-EE---SEMIHTRN 122 5667788888899999999999999999999999999999988554433333.32...23344443 PP >> INV_N Beta-fructofuranosidase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00083 1 20 52 .. 17 49 .. 5 74 .. 0.68 2 ? 2.4 0.0 0.25 3e+02 27 66 .. 68 114 .. 47 127 .. 0.52 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00083 INV_N 20 rrpllvalviasallvlvvlvalagv.....reagqad 52 r+ + a++i+ +++++ v+++l gv + + FUN_000412-T1 17 RKIIRDAILIFIGIILITVCFVLLGVaqsydK-----K 49 336779*******************9543331.....2 PP == domain 2 score: 2.4 bits; conditional E-value: 0.25 INV_N 27 lviasallvlvvlvalagv.......reagqadlvapdevavsetak 66 v as +l+++++++++ r +gq+ +++ + ++ + FUN_000412-T1 68 RVFASICFLLGFILMTISLwhlrslkRAQGQNRRLMEQQRLMGNHEE 114 33444444444444455555566666555555444333333333333 PP >> DUF3040 Protein of unknown function (DUF3040) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.5 0.0026 3.1 38 80 .. 17 84 .. 2 87 .. 0.56 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0026 DUF3040 38 rrrlrrlavlavllfvl.GlvllvlGvalaq.........................vvlgvvGfvvmla 80 r+ r a+l+ ++++l +++++lGva + + ++Gf++m++ FUN_000412-T1 17 RKIIRD-AILIFIGIILiTVCFVLLGVAQSYdkkdtrgdcdycdskkhanafrvfaSICFLLGFILMTI 84 222333.33333333333777777777766567777777777777777777666666666666666665 PP >> YiaAB yiaA/B two helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.3 3.5 4.3e+03 18 21 .. 28 31 .. 23 44 .. 0.52 2 ? 12.6 0.2 0.00014 0.17 1 23 [. 67 89 .. 67 96 .. 0.88 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 3.5 YiaAB 18 iGlw 21 iG++ FUN_000412-T1 28 IGII 31 4444 PP == domain 2 score: 12.6 bits; conditional E-value: 0.00014 YiaAB 1 figqswisfllallalaiGlwyl 23 f++++ i+fll++ +++i lw+l FUN_000412-T1 67 FRVFASICFLLGFILMTISLWHL 89 789999***************98 PP >> Claudin_2 PMP-22/EMP/MP20/Claudin tight junction # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 0.00042 0.51 62 108 .. 42 88 .. 33 99 .. 0.87 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00042 Claudin_2 62 ltqvsnpftteeeeivsfsvtlllgltrfvqvllilslvlivlgvvl 108 + q +++ t ++ ++ s++++ ++++f+ + ++l+++l+ + ++ FUN_000412-T1 42 VAQSYDKKDTRGDCDYCDSKKHANAFRVFASICFLLGFILMTISLWH 88 4567789999999****************************999885 PP >> DUF4131 Domain of unknown function (DUF4131) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 0.00022 0.27 8 55 .. 29 91 .. 21 108 .. 0.72 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00022 DUF4131 8 wllaallllllllllllr.....................rkrrrtllllllllllavlgaalraprpns 55 ++++ ++++l + ++ ++++++++++ll+++ ++++ ++ s FUN_000412-T1 29 GIILITVCFVL------LgvaqsydkkdtrgdcdycdskKHANAFRVFASICFLLGFILMTISLWHLRS 91 22233333333......223445578***********9999999999999*******999999888766 PP >> LapA_dom Lipopolysaccharide assembly protein A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.9 1.7 2.1e+03 27 36 .. 26 35 .. 23 47 .. 0.52 2 ? 12.0 0.6 0.00017 0.21 25 62 .. 73 105 .. 69 108 .. 0.62 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1.7 LapA_dom 27 fliGallgwl 36 +iG +l+ + FUN_000412-T1 26 IFIGIILITV 35 5556544332 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00017 LapA_dom 25 iafliGallgwllsllsylrlrrelrrlkkelkkleke 62 i+fl+G++l+ + + r l+r++ + ++l ++ FUN_000412-T1 73 ICFLLGFILMTISLWH-----LRSLKRAQGQNRRLMEQ 105 7888888888777773.....44555555555554433 PP >> Pox_A14 Poxvirus virion envelope protein A14 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 3.9 0.0041 4.9 32 62 .. 56 86 .. 18 117 .. 0.69 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0041 Pox_A14 32 efskststtdkawralsivsFilgivil.lgl 62 ++ s++ ++ a+r+ + ++F+lg +++ ++l FUN_000412-T1 56 DYCDSKKHAN-AFRVFASICFLLGFILMtISL 86 5566677665.9************87541444 PP >> FeoB_associated FeoB-associated Cys-rich membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.9 0.00041 0.49 4 40 .. 27 62 .. 24 75 .. 0.72 2 ? -2.1 0.0 5.9 7.2e+03 12 17 .. 76 81 .. 67 95 .. 0.56 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00041 FeoB_associated 4 Ivgaivv.aavayalrriikkkkkgsCgggCggCssns 40 +g+i++ + +++++++ +kk g+C+ C+s++ FUN_000412-T1 27 FIGIILItVCFVLLGVAQSYDKKDT--RGDCDYCDSKK 62 4677777555555577777777777..69*****9875 PP == domain 2 score: -2.1 bits; conditional E-value: 5.9 FeoB_associated 12 avayal 17 +++++l FUN_000412-T1 76 LLGFIL 81 333332 PP >> Sema4F_C Semaphorin 4F C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.06 73 83 111 .. 17 45 .. 3 53 .. 0.76 2 ? 6.6 0.2 0.0052 6.3 88 122 .. 71 106 .. 51 113 .. 0.71 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.06 Sema4F_C 83 ysvgvGlagfllGvvaasltllllerrrq 111 + ++ ++ ++G+++ +++++ll+ + FUN_000412-T1 17 RKIIRDAILIFIGIILITVCFVLLGVAQS 45 455556677889************98775 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0052 Sema4F_C 88 GlagfllGvvaasltllller.rrqrrrqrellare 122 ++fllG+++ ++ l l +r + ++r l+ ++ FUN_000412-T1 71 ASICFLLGFILMTISLWHLRSlKRAQGQNRRLMEQQ 106 4579********999986655155555667777665 PP >> DUF5408 Family of unknown function (DUF5408) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 2.3 4.3 5.2e+03 13 25 .. 24 36 .. 12 43 .. 0.51 2 ? 9.4 0.0 0.0012 1.4 15 54 .. 70 106 .. 60 113 .. 0.74 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 4.3 DUF5408 13 ikialvccvitii 25 i i + +it+ FUN_000412-T1 24 ILIFIGIILITVC 36 3333333344444 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0012 DUF5408 15 ialvccvitiifatlslwvllnqitatanlsknqkileqk 54 a +c ++ i+ t+slw l a +n++++eq+ FUN_000412-T1 70 FASICFLLGFILMTISLWHLRSLKRAQ---GQNRRLMEQQ 106 4789**************997655443...4566666666 PP >> Herpes_UL73 UL73 viral envelope glycoprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.8 2.2 2.7e+03 44 58 .. 24 38 .. 22 42 .. 0.58 2 ? 10.7 0.5 0.00049 0.59 29 57 .. 58 86 .. 55 90 .. 0.93 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2.2 Herpes_UL73 44 iwallnvlvvivall 58 i++++++++++v ++ FUN_000412-T1 24 ILIFIGIILITVCFV 38 555556555555554 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00049 Herpes_UL73 29 CsadtyslslsSFssiwallnvlvvival 57 C ++ + ++ F+si +ll+ ++++++l FUN_000412-T1 58 CDSKKHANAFRVFASICFLLGFILMTISL 86 999**********************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1780 (0.069681); expected 510.9 (0.02) Passed bias filter: 1156 (0.0452535); expected 510.9 (0.02) Passed Vit filter: 131 (0.00512821); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 21 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.46 # Mc/sec: 1140.44 // Query: FUN_000413-T1 [L=174] Description: FUN_000413 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.1 13.6 0.3 0.15 13.1 0.2 1.4 1 BIg21 Bacterial Immunoglobulin-like 21 Domain annotation for each model (and alignments): >> BIg21 Bacterial Immunoglobulin-like 21 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.2 5.9e-06 0.15 25 90 .. 103 170 .. 77 173 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.9e-06 BIg21 25 ltrgdaknRqgekkksvddedvtvklegesgastqt..kytgvTdadGqltltvtqpkglGlkTplsv 90 + r +a +R++++ k +++d ++ e++s +s+ + ++T ++G + ++++ + g + Tpl v FUN_000413-T1 103 VLRMQAIERSNSQSKERHGKDPLLQAEQDSQSSSVSanNGGDTTVENGRVAVEIESDRGGQISTPLIV 170 557889999999999999999999999888876665434444***********************988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (174 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 666 (0.0260716); expected 510.9 (0.02) Passed bias filter: 516 (0.0201996); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1701.50 // Query: FUN_000414-T1 [L=328] Description: FUN_000414 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-45 155.8 12.6 2.5e-45 155.5 12.6 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 2.3e-07 30.9 14.5 3.2e-07 30.5 14.5 1.2 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 6.5e-07 29.5 15.6 1.1e-06 28.7 15.6 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.04 14.8 4.3 1 10.4 0.2 2.8 2 Gate Nucleoside recognition 0.057 13.8 0.8 0.057 13.8 0.8 2.4 3 Herpes_US9 Alphaherpesvirus tegument protein US9 0.17 12.4 0.3 0.17 12.4 0.3 3.9 5 PLDc_N Phospholipase_D-nuclease N-terminal Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 155.5 12.6 5.8e-49 2.5e-45 1 260 [] 28 283 .. 28 283 .. 0.93 Alignments for each domain: == domain 1 score: 155.5 bits; conditional E-value: 5.8e-49 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvfgevlCklvtaldv..vnltasillltaisiDRYlaIvkplky 93 gN lV+lv++r++ +rt+ n++l+nLavaD+lv+l+ +p + ++ ++ + g+vlC+l+t v v + +s+++l++i+i+RY +++ p+ + FUN_000414-T1 28 GNSLVCLVVIRHQDMRTAINYLLMNLAVADMLVGLFFTPQYIFMHMfTHPGGLAGNVLCRLLTGSNVawVGGAVSVFTLVVIAIERYSSVMDPFGN 123 8**************************************999766648889999********98776226678*********************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 k + tkrr +v+i + W+++l++ +p +++ k+++ ++ ++C ++e +++ ++ytl+++++ + p++++ +y+r++ tl+ ++ +++ FUN_000414-T1 124 KGRLTKRRLKVIIPMSWLFGLVINVPGFVV---KNFD--EKAKFCIRRYSE--EWMGKTYTLIWFLVLAFFPVVIMGALYFRVVYTLWFQRVEHSA 212 ****************************95...4554..799*******99..78*************************************9998 PP ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 +++ r +++++ t+++v v+f++cw+ i+ l++ + ++ + a+ + + ++ns++NPi+Y FUN_000414-T1 213 fdfRQQGVLRVRKRVTLTVVTVSVIFAMCWMSGAITYLVALF---SPVFGAGDVAYVTQSTVVLFNSAVNPIVY 283 6666666667777*****************************...****************************9 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 14.5 7.4e-11 3.2e-07 16 281 .. 31 298 .. 18 300 .. 0.78 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 7.4e-11 7TM_GPCR_Srv 16 licllklrkrsktfkttFYklllqhaiaDiitllvyivgavfrklgwieefyfelqeyyaaiyyniayytliirctgivlLslqRllaillPisrl 111 l+cl+ +r++ +t+ ll+ a+aD++ l+++ + f + + + + + n+a++ + + + v+++++R++ ++ P FUN_000414-T1 31 LVCLVVIRHQD--MRTAINYLLMNLAVADMLVGLFFTPQYIFMHMFTHPGGLAGNVLCRLLTGSNVAWVGGAVSVFTLVVIAIERYSSVMDPF-GN 123 68999999888..999999999999999999887766666666664444444444444455899*****************************.66 PP 7TM_GPCR_Srv 112 tkivqsaklwkiilvywlvgllislvvlkdtdieydneenmpvvadksvierftlialivvvvtciili.iayvllfvvlrkkk.k....kksqtk 201 + +++ +l ii + wl gl+i++ ++ +++ + + + +++ + ++ tli ++v++++ ++++ ++y+ ++++l ++ + q+ FUN_000414-T1 124 KGRLTKRRLKVIIPMSWLFGLVINVPGFVVKNFDEKAKFCIRRYSEEWMGKTYTLIWFLVLAFFPVVIMgALYFRVVYTLWFQRvEhsafDFRQQG 219 7777777999****************9999987665555599999999999999999988877755555267876666665444324578444455 PP 7TM_GPCR_Srv 202 skslkrevrLa.iqvlilvlaqliilifyilklyfsqtlntdpifylRalYpilsgllsyinPylllilskdlrkqvlkrl 281 ++ v L+ + v+++++++ + + l++ fs + ++ + y+ ++ + s +nP++ + ++++++++ ++ FUN_000414-T1 220 VLRVRKRVTLTvVTVSVIFAMCWMSGAITYLVALFSPVFGAGDVAYV--TQSTVVLFNSAVNPIVYALVNQQFSRKIKYMM 298 5555666666515677777777777788888999999999999****..888999999*****************997765 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.7 15.6 2.6e-10 1.1e-06 2 256 .. 23 297 .. 22 298 .. 0.76 Alignments for each domain: == domain 1 score: 28.7 bits; conditional E-value: 2.6e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv..llltgtq..lkreeCFll..iivyvfgltaqsvllLvigiDlliavk 91 v+ ++GN+l+ l++++++ +r+ +++L++ +++ad+l+ ++ ++ + +++t+ C ll + v+ +g +++ l+vi+i + v+ FUN_000414-T1 23 VLNVVGNSLVCLVVIRHQDMRTAINYLLMNLAVADMLVGLFFTPQYIfmHMFTHPGglAGNVLCRLLtgSNVAWVGGAVSVFTLVVIAIERYSSVM 118 7889********************************9866655554422555432211345568655225678899999999************** PP 7TM_GPCR_Srsx 92 fPirYrllskekYllillifpvlyssiilvlgflqrdde.tiivCapplala..gkas.eiftlsslii.nvivllvylvliii..lkkkkek... 177 P+ + +++ l + + + l+ ++i v gf++ + + + +C + + gk++ i+ l ++ vi+ +y+ ++ + +++ +++ FUN_000414-T1 119 DPFGNKGRLTKRRLKVIIPMSWLFGLVINVPGFVVKNFDeKAKFCIRRYSEEwmGKTYtLIWFLVLAFFpVVIMGALYFRVVYTlwFQRVEHSafd 214 ****99999999999999999***************9665999**987775411444423333333333034444667666666334444444888 PP 7TM_GPCR_Srsx 178 .kkssskkvlkslkvtvv....ififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +++ + +v k++++tvv if ++W+ i v+l + + + ++ +++vl++++ n +V+ + ++++ ++++ + FUN_000414-T1 215 fRQQGVLRVRKRVTLTVVtvsvIFAMCWMSGAITYLVALFSPVFGAGD-VAYVTQSTVVLFNSAVNPIVYALVNQQFSRKIKYM 297 88999999999999998544448999***********99888887776.667778899999****************9999877 PP >> Gate Nucleoside recognition # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.7 0.011 49 7 68 .. 101 154 .. 95 202 .. 0.63 2 ? 10.4 0.2 0.00024 1 3 69 .. 226 290 .. 225 311 .. 0.88 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.011 Gate 7 iivffsvlisiLedsglldrigkllepllrp.lglkplpgkaaialllgfaakevgvpllatl 68 + vf +v+i+i ++s+++d +g+ ++l ++ l + +++l+g++ ++vp++ FUN_000414-T1 101 VSVFTLVVIAIERYSSVMDPFGNK-GRLTKRrL-----KVIIPMSWLFGLV---INVPGFVVK 154 568999999999999999999999.66766634.....4555555666666...555555443 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00024 Gate 3 kvlpiivffsvlisiLedsglldrigkllepllrplglkplpgkaaialllgfaakevgvpllatly 69 +v ++v +sv+ ++ sg++ +++ l++p++ g+ + ++++ l+ + + + ++++l+++++ FUN_000414-T1 226 RVTLTVVTVSVIFAMCWMSGAITYLVALFSPVFGA-GDVAYVTQSTVVLFNSAV-NPIVYALVNQQF 290 688899*****************************.989999*****9999999.999999998775 PP >> Herpes_US9 Alphaherpesvirus tegument protein US9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 1.6 6.8e+03 24 51 .. 36 63 .. 32 72 .. 0.64 2 ? -3.9 0.4 4.5 1.9e+04 37 48 .. 177 188 .. 175 199 .. 0.56 3 ? 13.8 0.8 1.3e-05 0.057 20 57 .. 216 251 .. 215 260 .. 0.88 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.6 Herpes_US9 24 klrrRkkrtfCvitliivllvAvlsaaF 51 ++r+ rt +l+ + +l + F FUN_000414-T1 36 VIRHQDMRTAINYLLMNLAVADMLVGLF 63 5777777776655555555555665554 PP == domain 2 score: -3.9 bits; conditional E-value: 4.5 Herpes_US9 37 tliivllvAvls 48 tli l++A FUN_000414-T1 177 TLIWFLVLAFFP 188 556566666543 PP == domain 3 score: 13.8 bits; conditional E-value: 1.3e-05 Herpes_US9 20 kyqsklrrRkkrtfCvitliivllvAvlsaaFalGall 57 ++q +lr Rk+ t v+t+ +++ + +s+a +l+ FUN_000414-T1 216 RQQGVLRVRKRVTLTVVTVSVIFAMCWMSGAI--TYLV 251 89*****************9999999999997..6665 PP >> PLDc_N Phospholipase_D-nuclease N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.5 4.1 1.8e+04 24 32 .. 20 28 .. 20 28 .. 0.77 2 ? -3.5 0.1 3.6 1.6e+04 3 11 .. 102 110 .. 100 116 .. 0.65 3 ? -1.1 0.6 0.67 2.9e+03 20 34 .. 139 152 .. 129 153 .. 0.81 4 ? 12.4 0.3 3.9e-05 0.17 16 31 .. 175 190 .. 162 190 .. 0.81 5 ? 0.1 0.1 0.28 1.2e+03 23 33 .. 250 260 .. 244 261 .. 0.81 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 4.1 PLDc_N 24 vilflPvlG 32 ++++l+v+G FUN_000414-T1 20 ILVVLNVVG 28 577899988 PP == domain 2 score: -3.5 bits; conditional E-value: 3.6 PLDc_N 3 aiialidii 11 ++++l++i FUN_000414-T1 102 SVFTLVVIA 110 667777765 PP == domain 3 score: -1.1 bits; conditional E-value: 0.67 PLDc_N 20 aWllvilflPvlGpi 34 Wl+ ++ ++v G++ FUN_000414-T1 139 SWLFGLV-INVPGFV 152 6999888.8888876 PP == domain 4 score: 12.4 bits; conditional E-value: 3.9e-05 PLDc_N 16 ssklaWllvilflPvl 31 +++l+W+lv+ f+Pv+ FUN_000414-T1 175 TYTLIWFLVLAFFPVV 190 459***********97 PP == domain 5 score: 0.1 bits; conditional E-value: 0.28 PLDc_N 23 lvilflPvlGp 33 lv lf Pv+G+ FUN_000414-T1 250 LVALFSPVFGA 260 67788999996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (328 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1357 (0.0531219); expected 510.9 (0.02) Passed bias filter: 619 (0.0242317); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3282.46 // Query: FUN_000415-T1 [L=295] Description: FUN_000415 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-41 141.2 10.9 6.7e-41 141.0 10.9 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 4e-07 30.2 9.7 5.2e-07 29.8 9.7 1.2 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv ------ inclusion threshold ------ 0.032 15.0 0.1 0.058 14.2 0.1 1.4 1 Med16_C Mediator complex subunit 16, C-terminal 0.051 14.5 4.2 0.26 12.2 0.2 2.5 2 Gate Nucleoside recognition 0.072 13.5 1.3 0.072 13.5 1.3 2.0 2 Herpes_US9 Alphaherpesvirus tegument protein US9 0.15 12.6 0.3 0.15 12.6 0.3 3.6 3 PLDc_N Phospholipase_D-nuclease N-terminal Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 141.0 10.9 1.6e-44 6.7e-41 15 260 .] 1 242 [. 1 242 [. 0.93 Alignments for each domain: == domain 1 score: 141.0 bits; conditional E-value: 1.6e-44 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 15 lrtptnifllnLavaDllvlllvlpfalvyal.legdwvfgevlCklvtaldv..vnltasillltaisiDRYlaIvkplkykrirtkrralvlil 107 +rt+ n++l+nLavaD+lv+l+ +p + ++ ++ + v g+vlC+l+t v v + as+++l++i+i+RY a++ p+ +k + tkrr +v+i FUN_000415-T1 1 MRTSINYLLMNLAVADMLVGLFFTPQYIFMHMfTHPGGVAGKVLCRLLTGSNVawVGGAASVFTLVVIAIERYSAVMDPFGNKGRLTKRRLRVIIP 96 799**********************9986666589999**********98776226778************************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxx RF 7tm_1 108 vvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks...kkkksarkerk 200 + W+++l++ +p +++ k+++ ++ ++C ++e +++ ++ytl+++++ + p++++ +y+r++ tl+ ++ +++ +++ r +++ FUN_000415-T1 97 MSWIFGLVINFPGFVV---KNFD--EKAKFCIRRYSE--EWMGKTYTLIWFLVLAFFPVVIMGALYFRVVYTLWFQRVEHSAfdcRQQGVLRVRKR 185 *************995...4554..799*******99..78*************************************99998887777777788* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 201 alktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ ++++v v+f++cw+ i+ l++ + ++ + a+ + ++++ns++NPi+Y FUN_000415-T1 186 VTLMVVTVSVIFAMCWMSGAITYLVALF---SPVFGPGDVAYVSESTVIMFNSAVNPIVY 242 ****************************...9***************************9 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 9.7 1.2e-10 5.2e-07 79 282 .. 51 258 .. 7 259 .. 0.80 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 1.2e-10 7TM_GPCR_Srv 79 yniayytliirctgivlLslqRllaillPisrltkivqsaklwkiilvywlvgllislvvlkdtdieydneenmpvvadksvierftlialivvvv 174 n+a++ + + v+++++R++a++ P + +++ +l ii + w+ gl+i++ ++ +++ + + + +++ + ++ tli ++v+++ FUN_000415-T1 51 SNVAWVGGAASVFTLVVIAIERYSAVMDPF-GNKGRLTKRRLRVIIPMSWIFGLVINFPGFVVKNFDEKAKFCIRRYSEEWMGKTYTLIWFLVLAF 145 6899999***********************.667777778*******************9999987665555599999999999999999888877 PP 7TM_GPCR_Srv 175 tciili.iayvllfvvlrkkk.k.....kksqtkskslkrevrLaiqvlilvlaqliilifyilklyfsqtlntdpifylRalYpilsgllsyinP 263 + ++++ ++y+ ++++l ++ + ++q+ + +kr + + + v+++++++ + + l++ fs + + + y+ ++ + s +nP FUN_000415-T1 146 FPVVIMgALYFRVVYTLWFQRvEhsafdCRQQGVLRVRKRVTLMVVTVSVIFAMCWMSGAITYLVALFSPVFGPGDVAYV--SESTVIMFNSAVNP 239 75555526787666666544432457766666777777777777778888888888888888888999999999989***..778888899***** PP 7TM_GPCR_Srv 264 ylllilskdlrkqvlkrlk 282 ++ + ++++++++ ++ FUN_000415-T1 240 IVYALVNQQFSRKIKYMMC 258 *************988876 PP >> Med16_C Mediator complex subunit 16, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 1.4e-05 0.058 59 93 .. 247 279 .. 222 285 .. 0.76 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.4e-05 Med16_C 59 eqlankktslrrCvRCgsvsratsplvrkatavkt 93 +q ++ k++ C+RC+s+s+ +p +rk++ ++ FUN_000415-T1 247 QQFSR-KIKYMMCCRCRSISKGVHP-SRKEPNMQR 279 33333.555678*************.999888776 PP >> Gate Nucleoside recognition # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.7 0.044 1.9e+02 9 76 .. 62 134 .. 56 161 .. 0.67 2 ? 12.2 0.2 6.2e-05 0.26 3 69 .. 185 249 .. 184 277 .. 0.85 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.044 Gate 9 vffsvlisiLedsglldrigkllepllrp.lglkplpgkaaialllgfaakevgvpllatly........gidtpre 76 vf +v+i+i ++s ++d +g+ ++l ++ l +p+ +++l+++f +++v+++ ++ ++ FUN_000415-T1 62 VFTLVVIAIERYSAVMDPFGNK-GRLTKRrLR-VIIPMSWIFGLVINFP--GFVVKNFDEKAkfcirrysEEWMGKT 134 6889999999999999999999.666666477.6688888888888888..77777774333344444455555555 PP == domain 2 score: 12.2 bits; conditional E-value: 6.2e-05 Gate 3 kvlpiivffsvlisiLedsglldrigkllepllrplglkplpgkaaialllgfaakevgvpllatly 69 +v ++v +sv+ ++ sg++ +++ l++p++ p g+ + ++++ ++ + + + ++++l+++++ FUN_000415-T1 185 RVTLMVVTVSVIFAMCWMSGAITYLVALFSPVFGP-GDVAYVSESTVIMFNSAV-NPIVYALVNQQF 249 78899******************************.878888888888888888.888988887775 PP >> Herpes_US9 Alphaherpesvirus tegument protein US9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.4 4 1.7e+04 37 48 .. 136 147 .. 134 158 .. 0.56 2 ? 13.5 1.3 1.7e-05 0.072 20 57 .. 175 210 .. 173 214 .. 0.86 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 4 Herpes_US9 37 tliivllvAvls 48 tli l++A FUN_000415-T1 136 TLIWFLVLAFFP 147 556566666543 PP == domain 2 score: 13.5 bits; conditional E-value: 1.7e-05 Herpes_US9 20 kyqsklrrRkkrtfCvitliivllvAvlsaaFalGall 57 ++q +lr Rk+ t v+t+ +++ + +s+a +l+ FUN_000415-T1 175 RQQGVLRVRKRVTLMVVTVSVIFAMCWMSGAI--TYLV 210 8**********999999999999999999987..6665 PP >> PLDc_N Phospholipase_D-nuclease N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.8 0.32 1.4e+03 20 34 .. 98 111 .. 86 112 .. 0.82 2 ? 12.6 0.3 3.4e-05 0.15 16 31 .. 134 149 .. 121 149 .. 0.81 3 ? 0.8 0.2 0.16 7e+02 23 33 .. 209 219 .. 203 220 .. 0.85 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.32 PLDc_N 20 aWllvilflPvlGpi 34 W++ ++ +++ G++ FUN_000415-T1 98 SWIFGLV-INFPGFV 111 7999999.8888887 PP == domain 2 score: 12.6 bits; conditional E-value: 3.4e-05 PLDc_N 16 ssklaWllvilflPvl 31 +++l+W+lv+ f+Pv+ FUN_000415-T1 134 TYTLIWFLVLAFFPVV 149 459***********97 PP == domain 3 score: 0.8 bits; conditional E-value: 0.16 PLDc_N 23 lvilflPvlGp 33 lv lf Pv+Gp FUN_000415-T1 209 LVALFSPVFGP 219 67788999997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1085 (0.0424741); expected 510.9 (0.02) Passed bias filter: 458 (0.0179291); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.26u 0.43s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3006.59 // Query: FUN_000416-T1 [L=336] Description: FUN_000416 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-46 157.2 12.7 9.8e-46 156.8 12.7 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 5.5e-07 29.7 15.3 9e-07 29.0 15.3 1.3 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 5.1e-06 26.5 12.8 0.00049 19.9 12.8 2.2 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw ------ inclusion threshold ------ 0.02 15.8 3.6 0.36 11.8 0.1 2.9 2 Gate Nucleoside recognition 0.047 14.1 2.5 0.057 13.8 0.7 2.1 2 Herpes_US9 Alphaherpesvirus tegument protein US9 0.54 10.2 1.7 1.2 9.0 1.1 1.7 2 YobI-ATPase YobI-like P-loop NTPase Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 156.8 12.7 2.3e-49 9.8e-46 1 260 [] 28 283 .. 28 283 .. 0.93 Alignments for each domain: == domain 1 score: 156.8 bits; conditional E-value: 2.3e-49 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvfgevlCklvtaldv..vnltasillltaisiDRYlaIvkplky 93 gN lV+lv++r++ +rt+ n++l+nLavaD+lv+l+ +p + ++ ++ + g+vlC+l+t v v + as+++l++i+i+RY +++ p+ + FUN_000416-T1 28 GNSLVCLVVIRHQDMRTSINYLLMNLAVADMLVGLFFTPQYIFMHMfTHPGGLAGNVLCRLLTGSNVawVGGAASVFTLVVIAIERYSSVMDPFGN 123 8**************************************999766648889999********98776226778*********************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 k + tkrr +v+i + W+++l++ +p +++ k+++ ++ ++C ++e ++ ++ytl++++ + p++++ +y++++ tl+ ++ +++ FUN_000416-T1 124 KGRLTKRRLKVIIPMSWLFGLVINVPGFVV---KNFD--EKAKFCIRRYSE--EWLGKTYTLIWFLALAFFPVVIMGALYFQVVYTLWFQRVEHSA 212 ****************************95...4554..799*******99..7799***********************************9999 PP ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 +++ r +++++ ++++v v+f++cw+ i+ l++ + ++ + a+ + + ++ns++NPi+Y FUN_000416-T1 213 fdcRQQGVLRVRKRVTLMVVTVSVIFAMCWMSGAITYLVALF---SPVFGAGDVAYVTQSTVVMFNSAVNPIVY 283 8887777777788*****************************...****************************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 15.3 2.1e-10 9e-07 2 256 .. 23 297 .. 22 298 .. 0.77 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 2.1e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv..llltgt.q.lkreeCFll..iivyvfgltaqsvllLvigiDlliavk 91 v+ ++GN+l+ l++++++ +r+ +++L++ +++ad+l+ ++ ++ + +++t+ C ll + v+ +g +a+ l+vi+i + v+ FUN_000416-T1 23 VLNVVGNSLVCLVVIRHQDMRTSINYLLMNLAVADMLVGLFFTPQYIfmHMFTHPgGlAGNVLCRLLtgSNVAWVGGAASVFTLVVIAIERYSSVM 118 7889********************************98666555544225554321213455686652256788999999999************* PP 7TM_GPCR_Srsx 92 fPirYrllskekYllillifpvlyssiilvlgflqrdde.tiivCappla...lagkaseiftlssliinvivl.lvylvliii..lkkkkek... 177 P+ + +++ l + + + l+ ++i v gf++ + + + +C + l ++ i+ l ++ v+++ +y+ ++ + +++ +++ FUN_000416-T1 119 DPFGNKGRLTKRRLKVIIPMSWLFGLVINVPGFVVKNFDeKAKFCIRRYSeewLGKTYTLIWFLALAFFPVVIMgALYFQVVYTlwFQRVEHSafd 214 ****99999999999999999***************9665999**988773323344444555555555444442677766666334444444888 PP 7TM_GPCR_Srsx 178 .kkssskkvlkslkvtv....vififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +++ + +v k+++++v vif ++W+ i v+l + + + ++ +++v+++++ n +V+ + ++++ ++++ + FUN_000416-T1 215 cRQQGVLRVRKRVTLMVvtvsVIFAMCWMSGAITYLVALFSPVFGAGD-VAYVTQSTVVMFNSAVNPIVYALVNQQFSRKIKYM 297 88889999999999988444448999***********99888888776.66777889999999**************9999877 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 12.8 1.2e-07 0.00049 2 318 .. 17 300 .. 16 301 .. 0.77 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 1.2e-07 7TM_GPCR_Srw 2 vefilsivgviinifHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgv 97 ++ il+++ v+ n + +++ +r + + +sin l++ a++D+l l+ ++i +++++++ l + + +l+ + v +s++ v FUN_000416-T1 17 ANSILAVLNVVGNSLVCLVVIRHQDMRTSINYLLMNLAVADMLVGLFFTPQYI--FMHMFTHPGGLAGNVLCRLLTGS---NVAWVGGAASVFTLV 107 688999******99988888887766679*****************9999999..55555455555555555555444...455566677****** PP 7TM_GPCR_Srw 98 lmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifl 193 ++A+ R+ +v+ p+ nk +l+k + ++i + l+ l+i + ++ ++ e+ + C +y+ ++ l k+++ FUN_000416-T1 108 VIAIERYSSVMDPFGNKG-RLTKRRLKVIIP-MSWLFGLVINVPGFVVKNFDEKAKF------CI--------RRYS----------EEWLGKTYT 177 ****************96.698888876554.4566778888888888888866643......86........3344..........334667777 PP 7TM_GPCR_Srw 194 lidgilskiipsillpiltilLiieLrkakksrkkls.ksk.kneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileele.vif 286 li + + + p +++ l + ++ L+ + +++ +++ + +++ t +V+ ++++f + + +i+y+v+ + s + +++ v FUN_000416-T1 178 LIWFLALAFFPVVIMGALYFQVVYTLWFQRVEHSAFDcRQQgVLRVRKRVTLMVVTVSVIFAMCWMSGAITYLVALF-SPVF----GAGDVAyVTQ 268 7777888899999999999999999998888888777533334458999******************9****99665.4433....3444440445 PP 7TM_GPCR_Srw 287 sllltinsisHflicllmSsqYRktvkklfgc 318 s+++++ns++ +++ l+ q + +k +++c FUN_000416-T1 269 STVVMFNSAVNPIVYALVNQQFSRKIKYMMCC 300 78999**************************9 PP >> Gate Nucleoside recognition # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.7 0.03 1.3e+02 9 66 .. 103 152 .. 99 205 .. 0.66 2 ? 11.8 0.1 8.5e-05 0.36 3 69 .. 226 290 .. 225 317 .. 0.87 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.03 Gate 9 vffsvlisiLedsglldrigkllepllrp.lglkplpgkaaialllgfaakevgvplla 66 vf +v+i+i ++s+++d +g+ ++l ++ l + +++l+g++ ++vp++ FUN_000416-T1 103 VFTLVVIAIERYSSVMDPFGNK-GRLTKRrL-----KVIIPMSWLFGLV---INVPGFV 152 6888999999999999999998.66666634.....4555555555555...5555553 PP == domain 2 score: 11.8 bits; conditional E-value: 8.5e-05 Gate 3 kvlpiivffsvlisiLedsglldrigkllepllrplglkplpgkaaialllgfaakevgvpllatly 69 +v ++v +sv+ ++ sg++ +++ l++p++ g+ + ++++ ++ + + + ++++l+++++ FUN_000416-T1 226 RVTLMVVTVSVIFAMCWMSGAITYLVALFSPVFGA-GDVAYVTQSTVVMFNSAV-NPIVYALVNQQF 290 78899******************************.9999**********9999.999999998875 PP >> Herpes_US9 Alphaherpesvirus tegument protein US9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 1.9 8.1e+03 24 51 .. 36 63 .. 34 72 .. 0.66 2 ? 13.8 0.7 1.3e-05 0.057 20 57 .. 216 251 .. 214 259 .. 0.87 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 1.9 Herpes_US9 24 klrrRkkrtfCvitliivllvAvlsaaF 51 ++r+ rt +l+ + +l + F FUN_000416-T1 36 VIRHQDMRTSINYLLMNLAVADMLVGLF 63 6778777777666666666666666655 PP == domain 2 score: 13.8 bits; conditional E-value: 1.3e-05 Herpes_US9 20 kyqsklrrRkkrtfCvitliivllvAvlsaaFalGall 57 ++q +lr Rk+ t v+t+ +++ + +s+a +l+ FUN_000416-T1 216 RQQGVLRVRKRVTLMVVTVSVIFAMCWMSGAI--TYLV 251 8**********999999999999999999987..6665 PP >> YobI-ATPase YobI-like P-loop NTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.1 0.23 9.9e+02 99 161 .. 129 192 .. 121 206 .. 0.56 2 ? 9.0 1.1 0.00029 1.2 109 205 .. 190 288 .. 173 294 .. 0.72 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.23 YobI-ATPase 99 klkkkrllllallv.vlllllllllllaeklkklvkalskalllaaevallivlvllllvllll 161 k + k ++ +++l+ +++ + ++++++++ +k+ ++ +l ++ +l+ +l+l+++ ++++ FUN_000416-T1 129 KRRLKVIIPMSWLFgLVINVPGFVVKNFDEKAKFCIRRYSEEWLGKTYTLIWFLALAFFPVVIM 192 5555666666777745555556666777777777777666666663444444444433333333 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00029 YobI-ATPase 109 allvvlllllllllllaeklkklvkalskallla.aevallivlvllllvlllllllllsklkisklklkkaeik.leessesifdkyLdEivYfF 202 +++ +l + ++++l+++++ ++ ++ ++ +l + ++v+l++v+v +++++++++ ++ + +++++ ++ +++ ++s +f++ ++ ivY + FUN_000416-T1 190 VIMGALYFQVVYTLWFQRVEHSAFDCRQQGVLRVrKRVTLMVVTVSVIFAMCWMSGAITYLVALFSPVFGAGDVAyVTQSTVVMFNSAVNPIVYAL 285 23335555666666777777777777777777774555555666666666666777788888999999999999988999999***********98 PP YobI-ATPase 203 ekt 205 ++ FUN_000416-T1 286 VNQ 288 765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1402 (0.0548835); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3259.60 // Query: FUN_000417-T1 [L=336] Description: FUN_000417 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-45 154.5 12.2 5.9e-45 154.2 12.2 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.2e-07 31.9 13.2 1.7e-07 31.4 13.2 1.2 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 3.7e-07 30.3 15.8 7.2e-07 29.4 15.8 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 9.8e-05 22.3 14.4 0.0063 16.3 14.4 2.3 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw ------ inclusion threshold ------ 0.034 14.9 0.1 0.064 14.0 0.1 1.4 1 Med16_C Mediator complex subunit 16, C-terminal 0.26 11.3 0.7 0.47 10.4 0.7 1.5 1 YobI-ATPase YobI-like P-loop NTPase 0.27 12.2 8.3 0.28 12.2 0.3 3.0 3 Gate Nucleoside recognition 0.87 10.0 4.6 0.3 11.5 1.0 2.1 2 Herpes_US9 Alphaherpesvirus tegument protein US9 4.1 7.8 12.9 0.41 11.1 0.4 3.2 3 DUF4271 Domain of unknown function (DUF4271) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 154.2 12.2 2.1e-48 5.9e-45 1 260 [] 28 283 .. 28 283 .. 0.93 Alignments for each domain: == domain 1 score: 154.2 bits; conditional E-value: 2.1e-48 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvfgevlCklvtaldv..vnltasillltaisiDRYlaIvkplky 93 gN lV+lv++r++ +rt+ n++l+nLavaD+lv+l+ +p + + ++ + g++lC l+t v v + as+++l++i+i+RY a++ p+ + FUN_000417-T1 28 GNSLVCLVVIRHQDMRTAINYLLMNLAVADMLVGLFFTPQYIFMRMfAHPGGLAGKLLCSLLTGSNVawVGGAASVFTLVVIAIERYSAVMDPFGN 123 8**************************************999766648899999********98776226778*********************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 k + tkrr +v+i + W+++l++ +p +++ k+++ ++ ++C ++e +++ ++y l++++ + p++++ +y++++ tl+ ++ +++ FUN_000417-T1 124 KGRLTKRRLKVIIPMSWLFGLVINVPGFMV---KNFD--EKAKFCIRRYSE--EWMGKTYSLIWFLALAFFPVVIMGALYFQVVYTLWFQRVEHSA 212 ***************************995...4554..799*******99..789************************************9998 PP ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 +++ + +++++ +++++ v+f++cw+ i+ l++ + ++ + a+ + + ++ns++NPi+Y FUN_000417-T1 213 fdcRQQGVLKLRKRVTLMVVTISVIFAMCWMSGAITYLVAFF---SPVFGAGDVAYVTQSTVVMFNSAVNPIVY 283 7776667777777*****************************...****************************9 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 13.2 6e-11 1.7e-07 16 283 .] 31 300 .. 29 300 .. 0.77 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 6e-11 7TM_GPCR_Srv 16 licllklrkrsktfkttFYklllqhaiaDiitllvyivgavfrklgwieefyfelqeyyaaiyyniayytliirctgivlLslqRllaillPisrl 111 l+cl+ +r++ +t+ ll+ a+aD++ l+++ + f + + + + n+a++ + + v+++++R++a++ P FUN_000417-T1 31 LVCLVVIRHQD--MRTAINYLLMNLAVADMLVGLFFTPQYIFMRMFAHPGGLAGKLLCSLLTGSNVAWVGGAASVFTLVVIAIERYSAVMDPF-GN 123 67888888888..899999999999999998877766555555553344444333333346789*****************************.66 PP 7TM_GPCR_Srv 112 tkivqsaklwkiilvywlvgllislvvlkdtdieydneenmpvvadksvierftlialivvvvt.ciiliiayvllfvvlrkkk.k.....kksqt 200 + +++ +l ii + wl gl+i++ ++ +++ + + + +++ + ++ +li ++ ++++ ++i+ ++y++++++l ++ + ++ + FUN_000417-T1 124 KGRLTKRRLKVIIPMSWLFGLVINVPGFMVKNFDEKAKFCIRRYSEEWMGKTYSLIWFLALAFFpVVIMGALYFQVVYTLWFQRvEhsafdCRQ-Q 218 7777777999****************99999876655555999999999999999998888776245555779888887775554256774444.4 PP 7TM_GPCR_Srv 201 kskslkrevrLa.iqvlilvlaqliilifyilklyfsqtlntdpifylRalYpilsgllsyinPylllilskdlrkqvlkrlkc 283 +l++ v L + ++++++++ + + l+++fs + ++ + y+ ++ + s +nP++ + ++++++++ ++ c FUN_000417-T1 219 GVLKLRKRVTLMvVTISVIFAMCWMSGAITYLVAFFSPVFGAGDVAYV--TQSTVVMFNSAVNPIVYALVNQQFSRKIKYMMCC 300 44555555555405566666667777778888899999999999****..99999999*******************9888765 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 15.8 2.5e-10 7.2e-07 2 256 .. 23 297 .. 22 298 .. 0.77 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 2.5e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv..lllt..gtqlkreeCFll..iivyvfgltaqsvllLvigiDlliavk 91 v+ ++GN+l+ l++++++ +r+ +++L++ +++ad+l+ ++ ++ + +++ g + C ll + v+ +g +a+ l+vi+i + av+ FUN_000417-T1 23 VLNVVGNSLVCLVVIRHQDMRTAINYLLMNLAVADMLVGLFFTPQYIfmRMFAhpGGLAGKLLCSLLtgSNVAWVGGAASVFTLVVIAIERYSAVM 118 7889********************************9866555444411233211334556689766225678899999999************** PP 7TM_GPCR_Srsx 92 fPirYrllskekYllillifpvlyssiilvlgflqrdde.tiivCappla...lagkaseiftlssliinvivl.lvylvliii..lkkkkek... 177 P+ + +++ l + + + l+ ++i v gf++ + + + +C + + ++ s i+ l ++ v+++ +y+ ++ + +++ +++ FUN_000417-T1 119 DPFGNKGRLTKRRLKVIIPMSWLFGLVINVPGFMVKNFDeKAKFCIRRYSeewMGKTYSLIWFLALAFFPVVIMgALYFQVVYTlwFQRVEHSafd 214 ****99999999999999999***************9665999**987773324444445555555555554442677766666334444444888 PP 7TM_GPCR_Srsx 178 .kkssskkvlkslkvtv....vififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +++ + k+ k+++++v vif ++W+ i v++ + + + ++ +++v+++++ n +V+ + ++++ ++++ + FUN_000417-T1 215 cRQQGVLKLRKRVTLMVvtisVIFAMCWMSGAITYLVAFFSPVFGAGD-VAYVTQSTVVMFNSAVNPIVYALVNQQFSRKIKYM 297 88899999999999998444448999*********9999888887776.6677788999999***************9999877 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 14.4 2.2e-06 0.0063 2 318 .. 17 300 .. 16 301 .. 0.76 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 2.2e-06 7TM_GPCR_Srw 2 vefilsivgviinifHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgv 97 ++ il+++ v+ n + +++ +r + + ++in l++ a++D+l l+ ++i +++++ + l + + ++l+ + + v +s++ v FUN_000417-T1 17 ANSILAVLNVVGNSLVCLVVIRHQDMRTAINYLLMNLAVADMLVGLFFTPQYI--FMRMFAHPGGLAGKLLCSLLTGSNVAW---VGGAASVFTLV 107 688999******99988888887766679******************999999..555554666666666666666555555...55667****** PP 7TM_GPCR_Srw 98 lmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifl 193 ++A+ R+ v+ p+ nk +l+k + ++i + l+ l+i + ++ ++ e+ + C +y+ e + k++ FUN_000417-T1 108 VIAIERYSAVMDPFGNKG-RLTKRRLKVIIP-MSWLFGLVINVPGFMVKNFDEKAKF------CI---R-----RYS----EE------WMGKTYS 177 ****************96.698888776544.4566778888888888888866643......96...2.....333....22......2344445 PP 7TM_GPCR_Srw 194 lidgilskiipsillpiltilLiieLrkakksrkkls.ksk.kneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileele.vif 286 li + + + p +++ l + ++ L+ + +++ +++ + +++ t +V+ ++++f + + +i+y+v+f+ s + +++ v FUN_000417-T1 178 LIWFLALAFFPVVIMGALYFQVVYTLWFQRVEHSAFDcRQQgVLKLRKRVTLMVVTISVIFAMCWMSGAITYLVAFF-SPVF----GAGDVAyVTQ 268 555556677888888888888888888777777777653333456899*******************9*****9776.3423....3444440445 PP 7TM_GPCR_Srw 287 sllltinsisHflicllmSsqYRktvkklfgc 318 s+++++ns++ +++ l+ q + +k +++c FUN_000417-T1 269 STVVMFNSAVNPIVYALVNQQFSRKIKYMMCC 300 78999**************************9 PP >> Med16_C Mediator complex subunit 16, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.1 2.2e-05 0.064 60 94 .. 289 321 .. 263 326 .. 0.76 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.2e-05 Med16_C 60 qlankktslrrCvRCgsvsratsplvrkatavktl 94 q ++ k++ C+RC+s+s+ +p +rk++ ++ + FUN_000417-T1 289 QFSR-KIKYMMCCRCRSISKGVHP-SRKEPNMQHI 321 3333.455678*************.9999888765 PP >> YobI-ATPase YobI-like P-loop NTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.7 0.00017 0.47 109 205 .. 190 288 .. 123 294 .. 0.77 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00017 YobI-ATPase 109 allvvlllllllllllaeklkklvkalskallla.aevallivlvllllvlllllllllsklkisklklkkaeik.leessesifdkyLdEivYfF 202 +++ +l + ++++l+++++ ++ ++ ++ +l+ ++v+l++v++ +++++++++ ++ + +++++ ++ +++ ++s +f++ ++ ivY + FUN_000417-T1 190 VIMGALYFQVVYTLWFQRVEHSAFDCRQQGVLKLrKRVTLMVVTISVIFAMCWMSGAITYLVAFFSPVFGAGDVAyVTQSTVVMFNSAVNPIVYAL 285 22225555555566666666777777777777664555555555566666666677777888899999999999988999999***********98 PP YobI-ATPase 203 ekt 205 ++ FUN_000417-T1 286 VNQ 288 765 PP >> Gate Nucleoside recognition # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 1.4 4.1e+03 34 34 .. 70 70 .. 17 109 .. 0.66 2 ? 3.7 0.7 0.041 1.2e+02 10 88 .. 104 186 .. 99 203 .. 0.65 3 ? 12.2 0.3 9.8e-05 0.28 3 69 .. 226 290 .. 225 314 .. 0.88 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.4 Gate 34 l 34 + FUN_000417-T1 70 F 70 1 PP == domain 2 score: 3.7 bits; conditional E-value: 0.041 Gate 10 ffsvlisiLedsglldrigkllepllrplglkplpgkaaialllgfaakevgvpllatly.............gidtprerlaallftslst 88 f +v+i+i ++s ++d +g+ ++l ++ +l + +++l+g++ ++vp+++ ++ ++ ++++ f++l++ FUN_000417-T1 104 FTLVVIAIERYSAVMDPFGNK-GRLTKR----RLKVIIPMSWLFGLV---INVPGFMVKNfdekakfcirrysEEWMGKT-YSLIWFLALAF 186 666666666777777777766.555555....466788888889999...999999888557777777777766666666.55555555555 PP == domain 3 score: 12.2 bits; conditional E-value: 9.8e-05 Gate 3 kvlpiivffsvlisiLedsglldrigkllepllrplglkplpgkaaialllgfaakevgvpllatly 69 +v ++v +sv+ ++ sg++ +++ +++p++ g+ + ++++ ++ + + + ++++l+++++ FUN_000417-T1 226 RVTLMVVTISVIFAMCWMSGAITYLVAFFSPVFGA-GDVAYVTQSTVVMFNSAV-NPIVYALVNQQF 290 78899******************************.9999**********9999.999999998775 PP >> Herpes_US9 Alphaherpesvirus tegument protein US9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.1 2.6 7.4e+03 24 51 .. 36 63 .. 33 72 .. 0.65 2 ? 11.5 1.0 0.0001 0.3 20 59 .. 216 253 .. 214 255 .. 0.82 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.6 Herpes_US9 24 klrrRkkrtfCvitliivllvAvlsaaF 51 ++r+ rt +l+ + +l + F FUN_000417-T1 36 VIRHQDMRTAINYLLMNLAVADMLVGLF 63 6777777776666555555555665554 PP == domain 2 score: 11.5 bits; conditional E-value: 0.0001 Herpes_US9 20 kyqsklrrRkkrtfCvitliivllvAvlsaaFalGallsq 59 ++q +l+ Rk+ t v+t+ +++ + +s+a +l+ + FUN_000417-T1 216 RQQGVLKLRKRVTLMVVTISVIFAMCWMSGAI--TYLVAF 253 8**********998888888888888888887..777665 PP >> DUF4271 Domain of unknown function (DUF4271) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.3 0.044 1.2e+02 50 110 .. 17 75 .. 9 77 .. 0.80 2 ? 11.1 0.4 0.00015 0.41 115 152 .. 164 201 .. 123 207 .. 0.87 3 ? 0.7 1.2 0.21 6e+02 51 113 .. 232 290 .. 213 299 .. 0.49 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.044 DUF4271 50 fsiflflltllllslfvylllsefgllfslylasslllfliillilllffllKflllkllg 110 + +l +l+++ sl+++++ ++ + + + + l+++++ +++ lff+ +++++++++ FUN_000417-T1 17 ANSILAVLNVVGNSLVCLVVIRHQDMRTAI--NYLLMNLAVADMLVGLFFTPQYIFMRMFA 75 567899999999998888888886666554..46788888888999999999999999886 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00015 DUF4271 115 lkkiiseyifsllsyssllglllfplvillaysglslk 152 +++ +e++ + +s++++l+l++fp+vi+ a++ + + FUN_000417-T1 164 IRRYSEEWMGKTYSLIWFLALAFFPVVIMGALYFQVVY 201 5666799**********************876655544 PP == domain 3 score: 0.7 bits; conditional E-value: 0.21 DUF4271 51 siflflltllllslfvylllsefgllfslylasslllfliillilllffllKflllkllgslF 113 ++++++ +s ++ +l +f+ f+ + + + ++++++ + ++++l+++ F FUN_000417-T1 232 VTISVIFAMCWMSGAITYLVAFFSPVFG----AGDVAYVTQSTVVMFNSAVNPIVYALVNQQF 290 3333333333333333333333444444....3344444444444555555555555555444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1380 (0.0540223); expected 510.9 (0.02) Passed bias filter: 606 (0.0237228); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.31u 0.43s 00:00:00.74 Elapsed: 00:00:00.53 # Mc/sec: 2548.61 // Query: FUN_000418-T1 [L=515] Description: FUN_000418 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-97 326.9 0.0 3.4e-97 326.6 0.0 1.0 1 p450 Cytochrome P450 ------ inclusion threshold ------ 0.22 12.0 0.1 0.51 10.8 0.1 1.6 1 DUF8066 Family of unknown function (DUF8066) Domain annotation for each model (and alignments): >> p450 Cytochrome P450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 326.6 0.0 2.7e-101 3.4e-97 3 439 .. 45 489 .. 43 507 .. 0.89 Alignments for each domain: == domain 1 score: 326.6 bits; conditional E-value: 2.7e-101 p450 3 gptplplvgnllqlekkeelhsvltklqkkygpifrlklg.....skpvvvlsgpelvkevlikkgeefsgrpdealletlskafkgkgvlfange 93 +p lpl+g+l+ l +++ + + ++ k+y ++f l+ g + ++v++++pel++ v ik++++f+++ +++ ++ kg++ + g+ FUN_000418-T1 45 PPGGLPLIGHLFTLYRSGGFLEMVRVWTKQYPSMFILHPGfgfgiGGYMVYVTDPELIRFVAIKSAHKFERTQFLNWVV----PSVSKGLFGSVGK 136 5668******************9**************99943433479******************9999986666665....79*********** PP p450 94 kwrklRrlltptltsfgkl.sleeiveeeardlveklrkkagess.......elditellskaalnvicsilFgerfdlledekfsellkaveels 181 + +++r++ p++ s +l + +++ e +++lv+ + ++ +++ +++ ++ls+ +l+vi++ +Fg +f++ ++ ++ a+ + FUN_000418-T1 137 AHARQKRIIGPAFSSA-NLkGFLNVFLENSEKLVQHWCDQLLKNTaepkqfiDVKVLDDLSHLTLDVIGQSAFGYNFNSILGGDS-NISIAFATSL 230 ****************.666788888888777766555444444444449999999************************99966.6666666666 PP p450 182 ellssssvqlldlfpllkylptkllkklkeavkklkdlldklieerretldsa..kkkrrdfldalllakkekkgesklsdeelkatvlellfaGv 275 + ++++ +l+p+++ylp + +kk+++a+++ ++++ ++i+err++ + ++ ++d+ld+l++++ +++ +s ++deel+ +v+++++aG FUN_000418-T1 231 SAMDFKYLICKFLIPFFDYLPLPVNKKFQKAREISDNTVLEVIRERRRQKTEGshSSAKKDLLDLLMDMH-DEETDSRMNDEELRSQVFTFILAGN 325 7775555444455559*********************************9999988899**********8.666668******************* PP p450 276 dTtsstlswaLyeLaknPevqeklreEidevlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtlvivnlyalh 371 +T+s++++w+LyeLa+nP+vqeklr E++ ++gd++ +t++ + k++yl++v+kE+LRlh++++ ++R++++d +i+g+++p+Gt v++++ al+ FUN_000418-T1 326 ETSSVSMAWTLYELARNPQVQEKLRAEVEAAFGDSDDLTWEKVDKMHYLENVVKESLRLHSPAD-ITSRVALSDAEIGGHFVPAGTYVLLPVDALQ 420 ****************************************************************.889**************************** PP p450 372 rdpkvfpnPeeFdpeRFldekgns.rksfaflPFGaGpRnClGerlArmelklflatlLqnFevelqpe 439 r ++++nPe+Fdp+RF +++ ++ ++ ++PFG GpR+C+G ++A+me+k++la l++nF++ p+ FUN_000418-T1 421 RSLSFWSNPETFDPDRFQQKDDQTnILPYTYFPFGCGPRMCIGYKFATMEMKVVLAELVKNFSFGEVPG 489 ********************99777**************************************987665 PP >> DUF8066 Family of unknown function (DUF8066) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 4e-05 0.51 25 55 .. 13 43 .. 7 44 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 4e-05 DUF8066 25 vllvvllfvlyLayRfvvAveriAdAleriA 55 +lv+ +f+l+L + + ++ve+ + l+ri+ FUN_000418-T1 13 KFLVLCVFLLVLTWLLYKVVEERLSPLQRIP 43 589******************9999999985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (515 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 981 (0.0384028); expected 510.9 (0.02) Passed bias filter: 843 (0.0330006); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4934.31 // Query: FUN_000419-T1 [L=1930] Description: FUN_000419 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-176 587.8 0.0 5.4e-176 587.2 0.0 1.3 1 RdRP RNA dependent RNA polymerase 4.7e-25 89.0 0.9 1.3e-24 87.5 0.9 1.8 1 RdRP_head RdRP, head domain 1.3e-08 35.1 2.5 2.8e-07 30.8 2.1 3.0 2 PH_met_RdRP Metazoan RdRP associated PH-like domain 0.0059 17.2 0.3 0.021 15.5 0.3 2.0 1 DUF7752 Domain of unknown function (DUF7752) ------ inclusion threshold ------ 0.37 11.0 1.7 2.3 8.4 0.0 3.0 3 DUF7336 Domain of unknown function (DUF7336) Domain annotation for each model (and alignments): >> RdRP RNA dependent RNA polymerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 587.2 0.0 1.1e-179 5.4e-176 1 583 [. 410 983 .. 410 984 .. 0.91 Alignments for each domain: == domain 1 score: 587.2 bits; conditional E-value: 1.1e-179 RdRP 1 vtptrillegpeleksnrvlRrfkegsdrflrvqfpdedleq.rlnsevdseeevfervkkllkegikiagrkfeflafsnsqlrehsvwffapfe 95 +tpt+ ll +pel nrv+R + g+++ +r+ f+ded ++ ++ + +e+++erv +ll++ i+i+grkfefla+snsqlr+h++w+fa FUN_000419-T1 410 ITPTQRLLIPPELVAENRVIRDY--GHESAMRIAFRDEDFSKlLSTHRDSLNEVLQERVVSLLSKYIVIGGRKFEFLACSNSQLRDHGAWLFAV-- 501 79*********************..**************99954444445599***************************************94.. PP RdRP 96 esgervtveeirkwlgdfsnieqsvaKyaaRlgqafSktratvvkveeee.i.veeipD..........evrngkkiyv..........ftDGvGk 169 +ge ++++ir++lg++++i ++va y++R+gq+fS+t+++ v++e e e+i+D + + f+DG+G+ FUN_000419-T1 502 -DGE-HRAHDIRSSLGRLDEI-RCVATYVSRMGQCFSSTKEA-VTIEIGEgFkAEKIQDvevkfnnvffK--------CcqqvrsgkytFSDGIGR 585 .443.69**************.*******************5.5555555566999***84433333331........24666666667******* PP RdRP 170 iSrelarkiakelglkkeelPsafQiRlgGaKGvlavdkel...p.kdwielrpSmiKfeseeesrtLeivkaskkpkpayLnrqlIkiLedlgvp 261 iS +lar +a++l+l +++Psa+QiR++G+KG+la+d++ + ++ ++ r+Sm+Kf+s+ +r Lei+++sk++ +yLnrq I++L+ lgvp FUN_000419-T1 586 ISLALARTVADNLDL--DPIPSAYQIRFAGCKGMLAMDPRIrggNfREILQYRESMKKFDSN--HRVLEICETSKPN-LLYLNRQCIILLSGLGVP 676 ***************..69*******************999887355579*********887..566********99.****************** PP RdRP 262 devflelleealeeleealkdaelaaelleksgdpaeleellaellkagfepkelkdpflrsllkllvkkklrelkekarIpvp..ksatllgvaD 355 d+vf+ l++e+l++l+++l +++a+e l+ p l+ +a l ++g++ + ++pf+rsll +++k++l +l ++a+I +p +++ l+gv+D FUN_000419-T1 677 DDVFIGLQDEMLRNLASILLFESVALETLRFITIPGGLK--FALLSRSGIKVT--QEPFFRSLLLAVYKSRLGDLLRRAHIAIPetHGRLLMGVMD 768 *************************9*999776666665..556679999877..68***************************888********* PP RdRP 356 etgvLeegevfvqfssatve.eekektkllegkvlVaRnPalhpgDiqvvravdvpelrhlkdvvVFsqkGdrplpselsGGDlDGDlywviwdpe 450 etg L++g+vf+++s+++ e ++ + ++l+g+v++++nP+ hpgD++ ++avdv+ l+hl+d+vVF+ +G+rp+p+e+sG+DlDGD+y+v+w + FUN_000419-T1 769 ETGSLKYGQVFIRYSKFVSEpGK--ELEILHGRVVISKNPCFHPGDMRTFQAVDVEGLHHLVDCVVFPATGHRPHPNEMSGSDLDGDKYFVTWLDK 862 ****************8555444..59********************************************************************* PP RdRP 451 lefapakptneepadyeaakpkeldrevtvediadffveymksdvlGlianahlaiadqseegvkdekclkLaelhskaVDypKtGipvekkelpr 546 l p+ ++nee++d++a+k+k+++ +v+v+d+ +f +y+k+d+lG+ianahl++ad +e+g+++ +c+kLa++hs+aVD+pKtG + lp+ FUN_000419-T1 863 LI--PK-RRNEEAMDFTAPKKKTIEGKVEVSDMIEFISDYIKNDQLGIIANAHLVHADCDEKGIFSTECIKLAHMHSDAVDFPKTGECPT---LPK 952 *5..55.68899******************************************************************************...*** PP RdRP 547 elkkpkekPdfkekekkekkkkkyyksekilGkLyre 583 el +p+++Pdf+++ +k+ yks++ilGkL+r+ FUN_000419-T1 953 EL-RPEQYPDFMMNP-----RKPQYKSNRILGKLFRK 983 **.7999*****433.....3477***********98 PP >> RdRP_head RdRP, head domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.5 0.9 2.5e-28 1.3e-24 2 136 .. 1005 1174 .. 1004 1203 .. 0.89 Alignments for each domain: == domain 1 score: 87.5 bits; conditional E-value: 2.5e-28 RdRP_head 2 ydedlevpgfedfleeakawkenYdekLtqlmdyYrvkteeeiltGiillllkrdskkqg.....kdriklavneLrkea.............. 76 dedl+v g+e +leea+a +++Y++kL lm++Y+ k+e e++tG++ ++ r s k + ++ i+++ Lr ++ FUN_000419-T1 1005 LDEDLKVRGYERYLEEAEAARKHYNAKLEGLMSLYGLKNEGEVITGCLSRVNTRLSGKTDekfeaAQMIQASLATLRARTreafydefggeeav 1098 599*********************************************666666555555554579999********99999999999999999 PP RdRP_head 77 aseFeeskedeenlekkAsAwYqvtYhpairekkl................aflsFaWvagdvLlrikaesakrke 136 + eFee + ++++ +kAsAwY vtY++ + + l + +sF+Wv+ + L++ik +k ++ FUN_000419-T1 1099 MEEFEENGSFDDEVMMKASAWYMVTYDQVDQPQPLrssqrdhqtgdarneiKLISFPWVVDRILAEIKNAKQKERQ 1174 999999999999***************98887777888999****************************6554444 PP >> PH_met_RdRP Metazoan RdRP associated PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.8 2.1 5.5e-11 2.8e-07 8 205 .. 120 278 .. 116 290 .. 0.78 2 ? 0.4 0.0 0.11 5.5e+02 113 139 .. 1247 1272 .. 1227 1292 .. 0.81 Alignments for each domain: == domain 1 score: 30.8 bits; conditional E-value: 5.5e-11 PH_met_RdRP 8 ipleaiafGNilnggtFlnhwevsfpeetnseklqellkvlrelrkadikspmladFeHDrriltvrFavreeykkreveesnekgleeavyqlkv 103 ++ +++ fG+++n+gt++ hw+ + k ++ ++++FeHD ++l++ F + e++ + +++++ FUN_000419-T1 120 LQANSFGFGSFFNRGTYIEHWSSQQD--LLLIK----------------EKRIQIEFEHDTKLLVIAFLEKGETQ------------VFNDVRIEM 185 56789*****************9943..43332................568****************9997732............33459**** PP PH_met_RdRP 104 rynsIrr.iivdle..dekgedrvriyfqlnyPpeirrfrkkknkkgkkklesegkRvlswpegdrkedeesseeaiseSpvfclefkeed...sd 193 +y + ++d++ + + ++++++y+ l++Pp++ ++ k ++ + +kRv + + + +e++ ++v+cl+f+e+ ++ FUN_000419-T1 186 EYRHLETyLVIDNDsdETSFQKTIKLYIPLQFPPKVFQVIKHGEY-------TYNKRVIHFLR--------CYPEVLGSCSVLCLCFPENLqlnKA 266 ******9455599875555678899*************9999875.......55677665544........6899************998734334 PP PH_met_RdRP 194 eelydilsRLra 205 + +++RL FUN_000419-T1 267 NSPSALIARLSQ 278 566677777765 PP == domain 2 score: 0.4 bits; conditional E-value: 0.11 PH_met_RdRP 113 vdledekgedrvriyfqlnyPpeirr.f 139 d +++++rv+iy+++++ ++ + + FUN_000419-T1 1247 TDH--NDERHRVEIYLHFKWDASVPEqH 1272 444..8899***********99998743 PP >> DUF7752 Domain of unknown function (DUF7752) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.3 4e-06 0.021 2 52 .. 1328 1381 .. 1327 1424 .. 0.80 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 4e-06 DUF7752 2 vkrypgLdkllffllkWaekhklf...eksplreehlclLliqfglgqlkgedg 52 v+r p L +ll ++++W+++ ++ ++s l+ e+l++++i f+ + + ++ FUN_000419-T1 1328 VQRCPPLLHLLLIIMHWGRRRQINgyhQNSFLTDEQLAIIFITFCQKSGFINKL 1381 789999****************995555699*************9887776633 PP >> DUF7336 Domain of unknown function (DUF7336) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 1.9 9.8e+03 25 40 .. 100 115 .. 100 117 .. 0.84 2 ? -0.4 0.1 0.26 1.3e+03 21 31 .. 1624 1635 .. 1624 1648 .. 0.81 3 ? 8.4 0.0 0.00045 2.3 14 33 .. 1884 1905 .. 1860 1921 .. 0.83 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.9 DUF7336 25 EkAeklieeyklkyye 40 E Ae +i++ k+k+++ FUN_000419-T1 100 ESAEPAIDTFKYKSND 115 89******98888765 PP == domain 2 score: -0.4 bits; conditional E-value: 0.26 DUF7336 21 fsskEkAe.kli 31 +s+++kAe k++ FUN_000419-T1 1624 YSTEDKAEtKFL 1635 9*******6555 PP == domain 3 score: 8.4 bits; conditional E-value: 0.00045 DUF7336 14 eikiiGVfsskEkAe..kliee 33 e+ki+GVf+ k+ A+ k++++ FUN_000419-T1 1884 EVKICGVFDGKDSANakKVAQD 1905 69**********9997666664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1930 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 799 (0.0312781); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.58u 0.40s 00:00:00.98 Elapsed: 00:00:00.44 # Mc/sec: 17741.53 // Query: FUN_000420-T1 [L=165] Description: FUN_000420 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.8e-22 78.1 0.2 2.6e-21 76.7 0.1 1.6 2 Pentaxin Pentaxin family 1.7e-05 25.4 0.0 2.1e-05 25.2 0.0 1.2 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil ------ inclusion threshold ------ 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 Arteri_Gl Arterivirus GL envelope glycoprotein Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.013 1.1e+02 3 30 .. 25 50 .. 23 50 .. 0.85 2 ! 76.7 0.1 3e-25 2.6e-21 86 191 .. 47 154 .. 36 159 .. 0.91 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.013 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlC 30 + fPk+ +t+y+++ + L ++t+C FUN_000420-T1 25 LEFPKKGVTDYAQIW--GMRSLTQFTIC 50 67**********986..56789999999 PP == domain 2 score: 76.7 bits; conditional E-value: 3e-25 Pentaxin 86 vhiCasWesssGivelwvdGkplvk.kslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildW 179 iC++W s+G +++ dG + + + lkkgy+v+a s+ l qeqDs+G fd++qsl G l+++n+W y L ik+++++ ++++ +W FUN_000420-T1 47 FTICVTWRNSDGQWKIYKDGDLAKSgTDLKKGYSVHAAGSLTLTQEQDSLGDAFDATQSLQGMLTNVNVWSYTLPASTIKEMSRCCLaGRGDVYEW 142 569*****************886642679*******************************************************9985799***** PP Pentaxin 180 ralnyevrgevv 191 + y+++g+ + FUN_000420-T1 143 ANFIYDIKGKPH 154 ********9743 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 2.5e-09 2.1e-05 84 150 .. 49 125 .. 12 126 .. 0.77 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 2.5e-09 Laminin_G_3 84 vavtyd..ggtlrlYvnGeevgsstltga.ltkatggply.......iGrdnggdspfdGlidevriynraLsaeei 150 ++vt++ +g++++Y +G +++s+t + + ++g+l+ +G++ + +++++G++ +v++++++L a+ i FUN_000420-T1 49 ICVTWRnsDGQWKIYKDGDLAKSGTDLKKgYSVHAAGSLTltqeqdsLGDAFDATQSLQGMLTNVNVWSYTLPASTI 125 78889866688*************98777655556666651233333666667799999*************99988 PP >> Arteri_Gl Arterivirus GL envelope glycoprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 2.2e-05 0.19 86 134 .. 109 154 .. 99 159 .. 0.77 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.2e-05 Arteri_Gl 86 ayaacalaAlvlgvysfvvraarlrlclagryaitahtnfvldakGrif 134 +++ + + +l s +++++ r clagr + +nf+ d kG+ + FUN_000420-T1 109 MLTNVNVWSYTL-PASTIKEMS--RCCLAGRGDVYEWANFIYDIKGKPH 154 555555555566.345899999..99********************955 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (165 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 644 (0.0252104); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.51 # Mc/sec: 1306.79 // Query: FUN_000421-T1 [L=181] Description: FUN_000421 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-30 107.0 0.4 1.6e-30 106.8 0.4 1.0 1 Pentaxin Pentaxin family 2.6e-12 47.6 1.0 3.7e-12 47.1 1.0 1.2 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil ------ inclusion threshold ------ 0.012 15.6 0.0 0.016 15.3 0.0 1.2 1 DUF6386 Family of unknown function (DUF6386) 0.077 14.0 0.1 0.1 13.5 0.1 1.1 1 Laminin_G_2 Laminin G domain Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.8 0.4 2.5e-34 1.6e-30 23 189 .. 3 168 .. 1 174 [. 0.93 Alignments for each domain: == domain 1 score: 106.8 bits; conditional E-value: 2.5e-34 Pentaxin 23 PLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGivelwvdGkplvk.kslkkgy 117 L ++t+C++ +t+ + fsya k +n+lLi + + + l++g+ v + v+ + + + iC++W s+G +++ dG + + ++lk +y FUN_000421-T1 3 SLTQFTVCFWLKTTG-PIWTAFSYASKAASNDLLI--DCANSVYLSIGDLSVNTGVVINDGKFHQICVTWRNSDGQWKIYKDGDLAKEgTGLKIAY 95 5899********984.67899************98..66788999**************************************987643899**** PP Pentaxin 118 tvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrge 189 t++ + s+ +GqeqDs+G kfd+sqsl G l+++n+W y L ik+++++ ++++ +W + y +rg+ FUN_000421-T1 96 TIQVSGSLTQGQEQDSLGDKFDASQSLQGMLTNVNVWSYTLPASTIKEMSRCCLtGKGDVYEWSNFIYGIRGN 168 **************************************************9987579*************996 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.1 1.0 5.8e-16 3.7e-12 17 150 .. 5 141 .. 2 142 .. 0.82 Alignments for each domain: == domain 1 score: 47.1 bits; conditional E-value: 5.8e-16 Laminin_G_3 17 safTvsaWvkpdsapqssralvsessgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlrlYvnGeevgsstltga 110 ++fTv++W+k++ ++ ++ s++ + l +d ++++++++++ +v++g +++g++++++vt++ +g++++Y +G +++++t+ FUN_000421-T1 5 TQFTVCFWLKTTGPIWTAFSYA--SKAASNDLLIDCANSVYLSIGDL-----SVNTGVVINDGKFHQICVTWRnsDGQWKIYKDGDLAKEGTGLKI 93 68*********99886444444..88888888889899999999988.....69*******************76688*************99777 PP Laminin_G_3 111 .ltkatggplyiGrdn.......ggdspfdGlidevriynraLsaeei 150 t + +g+l+ G+++ + +++++G++ +v++++++L a+ i FUN_000421-T1 94 aYTIQVSGSLTQGQEQdslgdkfDASQSLQGMLTNVNVWSYTLPASTI 141 444477888887777755543335699999*************99988 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 2.5e-06 0.016 54 118 .. 71 138 .. 39 151 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.5e-06 DUF6386 54 GedGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++++ dla+e + y +sG++ G +d G++++ +s +G+l ++++ sy++ a FUN_000421-T1 71 NSDGQWKIYKDGDLAKEGtglKIAYTIQVSGSLTQGQEQDSLGDKFDASQSLQGMLTNVNVWSYTLPA 138 479******999**999833344455568***********************************9765 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 1.6e-05 0.1 46 123 .. 53 131 .. 38 133 .. 0.82 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.6e-05 Laminin_G_2 46 sgkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 +g +ndg++H++ v+++++ + ++ Dg+ ++ + + ++t+++ +sl G ++s ++ +++++++G l +++v FUN_000421-T1 53 TGVVINDGKFHQICVTWRNSDGQWKIykDGDLAKEGTGLKIAYTIQVSGSLTQGQE-QDSLGDKFDASQSLQGMLTNVNV 131 37788*************88888777558888888877777777888888888888.9999999999********99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 510 (0.0199648); expected 510.9 (0.02) Passed bias filter: 438 (0.0171462); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1829.04 // Query: FUN_000422-T1 [L=251] Description: FUN_000422 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 12.0 0.1 0.46 11.0 0.1 1.6 1 Pico_P2A Picornavirus core protein 2A Domain annotation for each model (and alignments): >> Pico_P2A Picornavirus core protein 2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 1.8e-05 0.46 41 61 .. 134 154 .. 116 175 .. 0.83 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 1.8e-05 Pico_P2A 41 ttgvyycksrrkyypvsvekp 61 + + yyc++++ yypv+++ FUN_000422-T1 134 RWAAYYCTHEKSYYPVVSQAT 154 5689************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (251 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1429 (0.0559405); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.48 # Mc/sec: 2091.18 // Query: FUN_000423-T1 [L=224] Description: FUN_000423 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-40 139.4 0.0 1.9e-40 139.2 0.0 1.0 1 Pentaxin Pentaxin family 2.5e-17 63.9 1.7 3.1e-17 63.6 1.7 1.1 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil 0.0064 17.4 0.2 0.0088 17.0 0.2 1.2 1 Laminin_G_2 Laminin G domain ------ inclusion threshold ------ 0.084 12.9 0.2 0.38 10.8 0.1 1.9 2 DUF6386 Family of unknown function (DUF6386) Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 139.2 0.0 2.9e-44 1.9e-40 3 189 .. 25 211 .. 23 217 .. 0.94 Alignments for each domain: == domain 1 score: 139.2 bits; conditional E-value: 2.9e-44 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fPk+ +t+yv++ + L ++t+C++ +t+ s fsya + dnelLi+ ek+g + l +g+ + v+ + + + iC++W ++G FUN_000423-T1 25 LEFPKQGVTDYVHIW--GMRSLTQFTVCFWLKTTQSSLGTPFSYASNAADNELLIYYEKNGRVFLGIGQVVLNTGVVVNDGKFHQICVTWRNTDGQ 118 67**********986..5688**************************************************9999********************* PP Pentaxin 99 velwvdGkp.lvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrge 189 ++ dG + v +lk+gyt++a s+ lGqeqDs+GG+fd++qsl G l+++++W y+L ik+++++ ++++ +W + y vrg+ FUN_000423-T1 119 WRIYKDGDLaKVGAGLKRGYTINAGGSLTLGQEQDSVGGGFDAKQSLQGMLTNVHVWSYALPASTIKEMSRCCLtGKGDVYEWSNFIYGVRGN 211 *******87256789*******************************************************9987579************9996 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.6 1.7 4.9e-21 3.1e-17 4 150 .. 33 184 .. 30 185 .. 0.85 Alignments for each domain: == domain 1 score: 63.6 bits; conditional E-value: 4.9e-21 Laminin_G_3 4 ddyvtlpd.aslttsafTvsaWvkpdsapqssralvs.essgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlrl 95 +dyv + +sl ++fTv++W+k+++++ ++ + ++ ++++ ++++ +g++++ ++ ++++g v++g++++++vt++ +g++r+ FUN_000423-T1 33 TDYVHIWGmRSL--TQFTVCFWLKTTQSSLGTPFSYAsNAADNELLIYYEKNGRVFLGIGQV-----VLNTGVVVNDGKFHQICVTWRntDGQWRI 121 556665433555..89*************98888444477889********99999988855.....89*******************76688*** PP Laminin_G_3 96 YvnGeevgsstltga.ltkatggplyiGrdn....gg...dspfdGlidevriynraLsaeei 150 Y +G +++ +++ + t ++gg+l++G+++ gg +++++G++ +v+++++aL a+ i FUN_000423-T1 122 YKDGDLAKVGAGLKRgYTINAGGSLTLGQEQdsvgGGfdaKQSLQGMLTNVHVWSYALPASTI 184 **********99888677799**********8886226669******************9988 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.2 1.4e-06 0.0088 42 123 .. 92 174 .. 72 176 .. 0.85 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 1.4e-06 Laminin_G_2 42 sllssgkklndgqwHsvsverkgrelt..lsvDgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 ++l +g +ndg++H++ v++++ + + Dg+ + a ++ +t+n+ +sl lG ++s +++++++G l +++v FUN_000423-T1 92 VVLNTGVVVNDGKFHQICVTWRNTDGQwrIYKDGDLAKVGAGLKRGYTINAGGSLTLGQE-QDSVGGGFDAKQSLQGMLTNVHV 174 34455999**************66555116669999999999999999***********9.99999999999*****9999976 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.18 1.2e+03 72 91 .. 74 93 .. 65 99 .. 0.71 2 ? 10.8 0.1 5.9e-05 0.38 55 118 .. 115 181 .. 98 194 .. 0.78 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.18 DUF6386 72 evlylrvpsGkvfvGagedv 91 e+l + G+vf+G g+ v FUN_000423-T1 74 ELLIYYEKNGRVFLGIGQVV 93 4445556789***9998765 PP == domain 2 score: 10.8 bits; conditional E-value: 5.9e-05 DUF6386 55 edGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++ + dla+ + y + G++ +G +d Gg+++ +s +G+l ++++ sy++ a FUN_000423-T1 115 TDGQWRIYKDGDLAKVGaglKRGYTINAGGSLTLGQEQDSVGGGFDAKQSLQGMLTNVHVWSYALPA 181 577777777777766652224556777889*********************************9865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 469 (0.0183598); expected 510.9 (0.02) Passed bias filter: 419 (0.0164024); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.33s 00:00:00.63 Elapsed: 00:00:00.43 # Mc/sec: 2106.48 // Query: FUN_000424-T1 [L=224] Description: FUN_000424 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-37 127.7 0.1 6.7e-37 127.6 0.1 1.0 1 Pentaxin Pentaxin family 1.4e-16 61.5 2.0 1.8e-16 61.1 2.0 1.1 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil ------ inclusion threshold ------ 0.059 14.3 0.1 0.083 13.9 0.1 1.3 1 Laminin_G_2 Laminin G domain Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 127.6 0.1 7.9e-41 6.7e-37 3 191 .. 25 213 .. 23 218 .. 0.93 Alignments for each domain: == domain 1 score: 127.6 bits; conditional E-value: 7.9e-41 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fP + +t+yv++ + L ++t+C++ t+ s fsya + dnelLi+ ekdg++ l +g+ + + + + + iC++W s+G+ FUN_000424-T1 25 LEFPSKGVTDYVQIW--GMRNLTQFTVCFWLNTTQSSYGTPFSYASNADDNELLIYYEKDGQVFLGIGEVVLNTGLVINDGQFHQICVTWRNSDGE 118 57**********986..56789**********************************************9998888889999*************** PP Pentaxin 99 velwvdGkplvk.kslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrgevv 191 +++ dG + + + lkkgy+v+a s+ l qeqDs+G fd++qsl G l+++n+W y L ik+++++ ++++ +W + y ++g+ + FUN_000424-T1 119 WKIYKDGDLAKSgTDLKKGYSVHAAGSLTLTQEQDSLGDAFDAKQSLQGMLTNVNVWSYTLPASTIKEMSRCCLaGKGDVYEWANFIYGIKGNPH 213 *******886642679*******************************************************998579*************99754 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.1 2.0 2.1e-20 1.8e-16 2 150 .. 31 184 .. 30 185 .. 0.82 Alignments for each domain: == domain 1 score: 61.1 bits; conditional E-value: 2.1e-20 Laminin_G_3 2 ggddyvtlpd.aslttsafTvsaWvkpdsapqssralvs.essgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtl 93 g +dyv++ ++l ++fTv++W++++++++ ++ + +++++++ ++++ dgq+++ ++ ++++g +++gq+++++vt++ +g++ FUN_000424-T1 31 GVTDYVQIWGmRNL--TQFTVCFWLNTTQSSYGTPFSYAsNADDNELLIYYEKDGQVFLGIGEV-----VLNTGLVINDGQFHQICVTWRnsDGEW 119 56889998654777..99*************98888444477888**************98855.....8********************76688* PP Laminin_G_3 94 rlYvnGeevgsstltga.ltkatggply.......iGrdnggdspfdGlidevriynraLsaeei 150 ++Y +G +++s+t + + ++g+l+ +G++ + +++++G++ +v++++++L a+ i FUN_000424-T1 120 KIYKDGDLAKSGTDLKKgYSVHAAGSLTltqeqdsLGDAFDAKQSLQGMLTNVNVWSYTLPASTI 184 ************98777645556666651233333666667799999*************99988 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.1 9.7e-06 0.083 41 123 .. 92 174 .. 64 176 .. 0.79 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 9.7e-06 Laminin_G_2 41 esllssgkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 + +l +g +ndgq+H++ v+++++ + ++ Dg+ +s + ++ + +++ +sl l ++s +a +++++++G l +++v FUN_000424-T1 92 V-VLNTGLVINDGQFHQICVTWRNSDGEWKIykDGDLAKSGTDLKKGYSVHAAGSLTLTQE-QDSLGDAFDAKQSLQGMLTNVNV 174 3.34448889*************88888776558888888887777776666666666665.88899999999999999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 531 (0.0207868); expected 510.9 (0.02) Passed bias filter: 467 (0.0182815); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 2189.05 // Query: FUN_000425-T1 [L=181] Description: FUN_000425 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-30 107.0 0.4 1.6e-30 106.8 0.4 1.0 1 Pentaxin Pentaxin family 2.6e-12 47.6 1.0 3.7e-12 47.1 1.0 1.2 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil ------ inclusion threshold ------ 0.012 15.6 0.0 0.016 15.3 0.0 1.2 1 DUF6386 Family of unknown function (DUF6386) 0.077 14.0 0.1 0.1 13.5 0.1 1.1 1 Laminin_G_2 Laminin G domain Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.8 0.4 2.5e-34 1.6e-30 23 189 .. 3 168 .. 1 174 [. 0.93 Alignments for each domain: == domain 1 score: 106.8 bits; conditional E-value: 2.5e-34 Pentaxin 23 PLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGivelwvdGkplvk.kslkkgy 117 L ++t+C++ +t+ + fsya k +n+lLi + + + l++g+ v + v+ + + + iC++W s+G +++ dG + + ++lk +y FUN_000425-T1 3 SLTQFTVCFWLKTTG-PIWTAFSYASKAASNDLLI--DCANSVYLSIGDLSVNTGVVINDGKFHQICVTWRNSDGQWKIYKDGDLAKEgTGLKIAY 95 5899********984.67899************98..66788999**************************************987643899**** PP Pentaxin 118 tvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrge 189 t++ + s+ +GqeqDs+G kfd+sqsl G l+++n+W y L ik+++++ ++++ +W + y +rg+ FUN_000425-T1 96 TIQVSGSLTQGQEQDSLGDKFDASQSLQGMLTNVNVWSYTLPASTIKEMSRCCLtGKGDVYEWSNFIYGIRGN 168 **************************************************9987579*************996 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.1 1.0 5.8e-16 3.7e-12 17 150 .. 5 141 .. 2 142 .. 0.82 Alignments for each domain: == domain 1 score: 47.1 bits; conditional E-value: 5.8e-16 Laminin_G_3 17 safTvsaWvkpdsapqssralvsessgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlrlYvnGeevgsstltga 110 ++fTv++W+k++ ++ ++ s++ + l +d ++++++++++ +v++g +++g++++++vt++ +g++++Y +G +++++t+ FUN_000425-T1 5 TQFTVCFWLKTTGPIWTAFSYA--SKAASNDLLIDCANSVYLSIGDL-----SVNTGVVINDGKFHQICVTWRnsDGQWKIYKDGDLAKEGTGLKI 93 68*********99886444444..88888888889899999999988.....69*******************76688*************99777 PP Laminin_G_3 111 .ltkatggplyiGrdn.......ggdspfdGlidevriynraLsaeei 150 t + +g+l+ G+++ + +++++G++ +v++++++L a+ i FUN_000425-T1 94 aYTIQVSGSLTQGQEQdslgdkfDASQSLQGMLTNVNVWSYTLPASTI 141 444477888887777755543335699999*************99988 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 2.5e-06 0.016 54 118 .. 71 138 .. 39 151 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.5e-06 DUF6386 54 GedGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++++ dla+e + y +sG++ G +d G++++ +s +G+l ++++ sy++ a FUN_000425-T1 71 NSDGQWKIYKDGDLAKEGtglKIAYTIQVSGSLTQGQEQDSLGDKFDASQSLQGMLTNVNVWSYTLPA 138 479******999**999833344455568***********************************9765 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 1.6e-05 0.1 46 123 .. 53 131 .. 38 133 .. 0.82 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.6e-05 Laminin_G_2 46 sgkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 +g +ndg++H++ v+++++ + ++ Dg+ ++ + + ++t+++ +sl G ++s ++ +++++++G l +++v FUN_000425-T1 53 TGVVINDGKFHQICVTWRNSDGQWKIykDGDLAKEGTGLKIAYTIQVSGSLTQGQE-QDSLGDKFDASQSLQGMLTNVNV 131 37788*************88888777558888888877777777888888888888.9999999999********99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 510 (0.0199648); expected 510.9 (0.02) Passed bias filter: 438 (0.0171462); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1796.57 // Query: FUN_000426-T1 [L=251] Description: FUN_000426 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 12.0 0.1 0.46 11.0 0.1 1.6 1 Pico_P2A Picornavirus core protein 2A Domain annotation for each model (and alignments): >> Pico_P2A Picornavirus core protein 2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 1.8e-05 0.46 41 61 .. 134 154 .. 116 175 .. 0.83 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 1.8e-05 Pico_P2A 41 ttgvyycksrrkyypvsvekp 61 + + yyc++++ yypv+++ FUN_000426-T1 134 RWAAYYCTHEKSYYPVVSQAT 154 5689************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (251 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1429 (0.0559405); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2506.47 // Query: FUN_000427-T1 [L=241] Description: FUN_000427 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-40 139.1 0.0 2.4e-40 138.8 0.0 1.1 1 Pentaxin Pentaxin family 3e-17 63.6 1.7 3.9e-17 63.3 1.7 1.1 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil 0.007 17.3 0.2 0.01 16.8 0.2 1.2 1 Laminin_G_2 Laminin G domain ------ inclusion threshold ------ 0.084 12.9 0.5 0.44 10.6 0.1 2.2 3 DUF6386 Family of unknown function (DUF6386) Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.8 0.0 3.8e-44 2.4e-40 3 189 .. 42 228 .. 40 234 .. 0.94 Alignments for each domain: == domain 1 score: 138.8 bits; conditional E-value: 3.8e-44 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fPk+ +t+yv++ + L ++t+C++ +t+ s fsya + dnelLi+ ek+g + l +g+ + v+ + + + iC++W ++G FUN_000427-T1 42 LEFPKQGVTDYVHIW--GMRSLTQFTVCFWLKTTQSSLGTPFSYASNAADNELLIYYEKNGRVFLGIGQVVLNTGVVVNDGKFHQICVTWRNTDGQ 135 67**********986..5688**************************************************9999********************* PP Pentaxin 99 velwvdGkp.lvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrge 189 ++ dG + v +lk+gyt++a s+ lGqeqDs+GG+fd++qsl G l+++++W y+L ik+++++ ++++ +W + y vrg+ FUN_000427-T1 136 WRIYKDGDLaKVGAGLKRGYTINAGGSLTLGQEQDSVGGGFDAKQSLQGMLTNVHVWSYALPASTIKEMSRCCLtGKGDVYEWSNFIYGVRGN 228 *******87256789*******************************************************9987579************9996 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.3 1.7 6.1e-21 3.9e-17 4 150 .. 50 201 .. 47 202 .. 0.85 Alignments for each domain: == domain 1 score: 63.3 bits; conditional E-value: 6.1e-21 Laminin_G_3 4 ddyvtlpd.aslttsafTvsaWvkpdsapqssralvs.essgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlrl 95 +dyv + +sl ++fTv++W+k+++++ ++ + ++ ++++ ++++ +g++++ ++ ++++g v++g++++++vt++ +g++r+ FUN_000427-T1 50 TDYVHIWGmRSL--TQFTVCFWLKTTQSSLGTPFSYAsNAADNELLIYYEKNGRVFLGIGQV-----VLNTGVVVNDGKFHQICVTWRntDGQWRI 138 556665433555..89*************98888444477889********99999988855.....89*******************76688*** PP Laminin_G_3 96 YvnGeevgsstltga.ltkatggplyiGrdn....gg...dspfdGlidevriynraLsaeei 150 Y +G +++ +++ + t ++gg+l++G+++ gg +++++G++ +v+++++aL a+ i FUN_000427-T1 139 YKDGDLAKVGAGLKRgYTINAGGSLTLGQEQdsvgGGfdaKQSLQGMLTNVHVWSYALPASTI 201 **********99888677799**********8886226669******************9988 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.2 1.6e-06 0.01 42 123 .. 109 191 .. 90 193 .. 0.85 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.6e-06 Laminin_G_2 42 sllssgkklndgqwHsvsverkgrelt..lsvDgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 ++l +g +ndg++H++ v++++ + + Dg+ + a ++ +t+n+ +sl lG ++s +++++++G l +++v FUN_000427-T1 109 VVLNTGVVVNDGKFHQICVTWRNTDGQwrIYKDGDLAKVGAGLKRGYTINAGGSLTLGQE-QDSVGGGFDAKQSLQGMLTNVHV 191 34455999**************66555116669999999999999999***********9.99999999999*****9999976 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 0.97 6.2e+03 111 130 .. 3 22 .. 1 24 [. 0.76 2 ? -0.1 0.0 0.14 9e+02 72 91 .. 91 110 .. 82 128 .. 0.72 3 ? 10.6 0.1 6.8e-05 0.44 55 118 .. 132 198 .. 115 211 .. 0.78 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 0.97 DUF6386 111 pGsyevkakrdedqielalv 130 Gs + ++k +e+q+ la++ FUN_000427-T1 3 AGSKQNHIKVEENQVMLAVI 22 57888888889999988876 PP == domain 2 score: -0.1 bits; conditional E-value: 0.14 DUF6386 72 evlylrvpsGkvfvGagedv 91 e+l + G+vf+G g+ v FUN_000427-T1 91 ELLIYYEKNGRVFLGIGQVV 110 44445567899999999866 PP == domain 3 score: 10.6 bits; conditional E-value: 6.8e-05 DUF6386 55 edGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++ + dla+ + y + G++ +G +d Gg+++ +s +G+l ++++ sy++ a FUN_000427-T1 132 TDGQWRIYKDGDLAKVGaglKRGYTINAGGSLTLGQEQDSVGGGFDAKQSLQGMLTNVHVWSYALPA 198 577777777777766652224556777889*********************************9865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 594 (0.0232531); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2358.07 // Query: FUN_000428-T1 [L=224] Description: FUN_000428 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-39 136.6 0.2 1.4e-39 136.3 0.2 1.0 1 Pentaxin Pentaxin family 1.2e-17 64.9 2.4 1.6e-17 64.5 2.4 1.1 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 0.00025 21.2 0.4 0.0032 17.5 0.1 2.0 2 DUF6386 Family of unknown function (DUF6386) 0.002 19.1 0.1 0.0028 18.6 0.1 1.2 1 Laminin_G_2 Laminin G domain ------ inclusion threshold ------ 0.19 12.0 0.0 0.28 11.4 0.0 1.2 1 Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor b Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 136.3 0.2 2.8e-43 1.4e-39 3 187 .. 25 209 .. 23 215 .. 0.93 Alignments for each domain: == domain 1 score: 136.3 bits; conditional E-value: 2.8e-43 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fP + +t+yv++ + L ++t+C++ t+ s fsya + dnelLi+ ekdg++ l +g+ + v+ + + + iC++W s+G FUN_000428-T1 25 LEFPSKGVTDYVQIW--GMRNLTQFTVCFWLNTTQSSYGTPFSYASNADDNELLIYYEKDGQVFLGIGEVVLNTGVVVNDGKFHQICVTWRNSEGQ 118 57**********986..56789************************************************999999999***************** PP Pentaxin 99 velwvdGkplv.kkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevr 187 e+++dG + + ++lk+gyt++a s+ lGqeqDs+G +fd++qsl G l+++n+W y L ik+++++ ++++ +W + vr FUN_000428-T1 119 WEIYMDGDLAKaDTGLKRGYTIHAAGSLTLGQEQDSVGDDFDADQSLQGMLTNVNVWSYSLPASTIKEMSRCCLtGKGDVYEWSNFINGVR 209 *******98652689*******************************************************998747899999998765555 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.5 2.4 3.2e-21 1.6e-17 2 150 .. 31 184 .. 30 185 .. 0.86 Alignments for each domain: == domain 1 score: 64.5 bits; conditional E-value: 3.2e-21 Laminin_G_3 2 ggddyvtlpd.aslttsafTvsaWvkpdsapqssralvs.essgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtl 93 g +dyv++ ++l ++fTv++W++++++++ ++ + +++++++ ++++ dgq+++ ++ ++++g v++g++++++vt++ g++ FUN_000428-T1 31 GVTDYVQIWGmRNL--TQFTVCFWLNTTQSSYGTPFSYAsNADDNELLIYYEKDGQVFLGIGEV-----VLNTGVVVNDGKFHQICVTWRnsEGQW 119 56889998654777..99*************98888444477888**************98855.....8********************65577* PP Laminin_G_3 94 rlYvnGeevgsstltga.ltkatggplyiGrdn.......ggdspfdGlidevriynraLsaeei 150 +Y +G +++ t+ + t ++g+l++G+++ + d++++G++ +v+++++ L a+ i FUN_000428-T1 120 EIYMDGDLAKADTGLKRgYTIHAAGSLTLGQEQdsvgddfDADQSLQGMLTNVNVWSYSLPASTI 184 ***********99988877779999***9999977754444499999*************99988 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.046 2.3e+02 69 91 .. 71 93 .. 48 103 .. 0.75 2 ! 17.5 0.1 6.3e-07 0.0032 55 118 .. 115 181 .. 98 193 .. 0.82 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.046 DUF6386 69 eesevlylrvpsGkvfvGagedv 91 +++e+l + G+vf+G ge v FUN_000428-T1 71 DDNELLIYYEKDGQVFLGIGEVV 93 444555566689*******9977 PP == domain 2 score: 17.5 bits; conditional E-value: 6.3e-07 DUF6386 55 edGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 +G++e+ + dla+ + + y ++G++ +G +d G+d++ d+s +G+l ++++ sy++ a FUN_000428-T1 115 SEGQWEIYMDGDLAKADtglKRGYTIHAAGSLTLGQEQDSVGDDFDADQSLQGMLTNVNVWSYSLPA 181 6899999999999999944444588889***********************************9755 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.1 5.5e-07 0.0028 40 123 .. 91 174 .. 64 176 .. 0.86 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 5.5e-07 Laminin_G_2 40 eesllssgkklndgqwHsvsverkgrelt..lsvDgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 e+ +l +g +ndg++H++ v+++++e + + +Dg+ ++ + ++ +t+++ +sl lG ++s + ++ ++++G l +++v FUN_000428-T1 91 EV-VLNTGVVVNDGKFHQICVTWRNSEGQweIYMDGDLAKADTGLKRGYTIHAAGSLTLGQE-QDSVGDDFDADQSLQGMLTNVNV 174 33.4445999**************6665544888**************99***********9.99999999999999**9999986 PP >> Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 5.5e-05 0.28 51 139 .. 44 130 .. 24 149 .. 0.85 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 5.5e-05 Toxin_R_bind_N 51 tnnFsisfWlripkkdnseskiIsskknnsGWkvslenneliftlidsngnekkivlsdyinkWvfitisndrlknklliyingklvan 139 F+++fWl +++ + s ++ ++ e+++ +f i + +v++ + k + i ++ ++ + iy++g l + FUN_000428-T1 44 LTQFTVCFWLNTTQSSYGTPFSYASNADDNELLIYYEKDGQVFLGIGEVVLNTGVVVN--DGKFHQICVTWRNSEGQWEIYMDGDLAKA 130 568***********99996666666677777899999999999999999999999999..6899*******99**********999775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 484 (0.018947); expected 510.9 (0.02) Passed bias filter: 416 (0.016285); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2203.56 // Query: FUN_000429-T1 [L=237] Description: FUN_000429 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.7e-34 117.2 0.5 1.3e-33 116.9 0.5 1.1 1 Pentaxin Pentaxin family 2e-14 54.5 3.8 2.9e-14 53.9 3.8 1.2 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil 0.0024 17.9 0.1 0.0042 17.1 0.1 1.5 1 DUF6386 Family of unknown function (DUF6386) ------ inclusion threshold ------ 0.014 16.4 0.2 0.022 15.7 0.2 1.3 1 Laminin_G_2 Laminin G domain Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 116.9 0.5 2e-37 1.3e-33 3 181 .. 42 217 .. 40 227 .. 0.91 Alignments for each domain: == domain 1 score: 116.9 bits; conditional E-value: 2e-37 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytd.LsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssG 97 + fP++ +t+yv++ + L ++t+C++++t+ L+ + fsya + +n+lLi + ++ + l++g++ v + v+ + e + iC++W s+G FUN_000429-T1 42 LEFPNKGVTDYVQIW--GWRSLTQFTVCFWVKTTgLK--WTAFSYASEAASNDLLI--DCVNSVFLSIGNRAVNTGVVINDGEFHQICVTWRNSDG 131 57**********986..5688***********99665..568************97..788999******************************** PP Pentaxin 98 ivelwvdGkplv.kkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgatl.sanildWra 181 +++ dG + + ++lk+gyt++a+ s+ lGqeqDs+GG+fd++qsl G l ++n+W y L+ ik+++++ l ++++ W++ FUN_000429-T1 132 QWKIYKDGDLAKaGTGLKRGYTIQASGSLTLGQEQDSVGGGFDAKQSLQGTLMNVNVWSYTLQASLIKELSRCCELgDGDVYVWED 217 ********98651589********************************************************99863678888875 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.9 3.8 4.5e-18 2.9e-14 2 150 .. 48 198 .. 47 199 .. 0.81 Alignments for each domain: == domain 1 score: 53.9 bits; conditional E-value: 4.5e-18 Laminin_G_3 2 ggddyvtlpd.aslttsafTvsaWvkpdsapqssralvsessgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlr 94 g +dyv++ +sl ++fTv++Wvk++ ++ ++ ++ s + + l +d +++++++++ av++g +++g++++++vt++ +g+++ FUN_000429-T1 48 GVTDYVQIWGwRSL--TQFTVCFWVKTTGLKWTAFSYA--SEAASNDLLIDCVNSVFLSIGNR-----AVNTGVVINDGEFHQICVTWRnsDGQWK 134 55788888776777..89*************8555555..44445555555555666666644.....8********************76688** PP Laminin_G_3 95 lYvnGeevgsstltga.ltkatggplyiGrdn....gg...dspfdGlidevriynraLsaeei 150 +Y +G +++ +t+ + t +++g+l++G+++ gg +++++G + +v++++++L a+ i FUN_000429-T1 135 IYKDGDLAKAGTGLKRgYTIQASGSLTLGQEQdsvgGGfdaKQSLQGTLMNVNVWSYTLQASLI 198 ***********99888777799**********8886226669*****************98765 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.1 6.6e-07 0.0042 54 118 .. 128 195 .. 96 202 .. 0.84 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 6.6e-07 DUF6386 54 GedGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++++ dla+ + y +sG++ +G +d Gg+++ +s +G+l+++++ sy+++a FUN_000429-T1 128 NSDGQWKIYKDGDLAKAGtglKRGYTIQASGSLTLGQEQDSVGGGFDAKQSLQGTLMNVNVWSYTLQA 195 47999999999999888733355588889***********************************9986 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.2 3.5e-06 0.022 44 123 .. 108 188 .. 96 190 .. 0.85 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 3.5e-06 Laminin_G_2 44 lssgkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 + +g +ndg++H++ v+++++ + ++ Dg+ ++ + ++ +t+++ +sl lG ++s +++++++G l +++v FUN_000429-T1 108 VNTGVVINDGEFHQICVTWRNSDGQWKIykDGDLAKAGTGLKRGYTIQASGSLTLGQE-QDSVGGGFDAKQSLQGTLMNVNV 188 3447789*************88887666669999999999999999***********9.99999999999999999999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (237 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 625 (0.0244666); expected 510.9 (0.02) Passed bias filter: 515 (0.0201605); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 2290.49 // Query: FUN_000430-T1 [L=238] Description: FUN_000430 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-32 112.7 0.1 2.8e-32 112.5 0.1 1.1 1 Pentaxin Pentaxin family 1.7e-14 54.7 2.3 2.3e-14 54.3 2.3 1.2 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil ------ inclusion threshold ------ 0.17 12.9 0.1 0.25 12.3 0.1 1.2 1 Laminin_G_2 Laminin G domain Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 112.5 0.1 3.3e-36 2.8e-32 3 191 .. 42 227 .. 40 232 .. 0.91 Alignments for each domain: == domain 1 score: 112.5 bits; conditional E-value: 3.3e-36 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fP++ +t+yv++ + L ++t+C++++t+ ++ fsya k +n+lLi + + l++g++ v + + + + + iC++W s+G+ FUN_000430-T1 42 LEFPNKGVTDYVQIW--GMRSLTQFTVCFWVKTTGP-KWTAFSYASKAASNDLLI--DCADSVYLSIGNRGVNTGLVINDGQFHQICVTWRNSDGE 132 57**********986..5688***********9865.5788************98..55667889999*999999999999*************** PP Pentaxin 99 velwvdGkplvk.kslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrgevv 191 +++ dG + + + lkkgy+v+a s+ l qeqDs+G fd++qsl G l+++n+W y L ik+++++ ++++ +W + y ++g+ + FUN_000430-T1 133 WKIYKDGDLAKSgTDLKKGYSVHAAGSLTLTQEQDSLGDAFDAKQSLQGMLTNVNVWSYTLPASTIKEMSRCCLaGKGDVYEWANFIYGIKGNPH 227 *******886642679*******************************************************998579*************99754 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.3 2.3 2.7e-18 2.3e-14 2 150 .. 48 198 .. 46 199 .. 0.80 Alignments for each domain: == domain 1 score: 54.3 bits; conditional E-value: 2.7e-18 Laminin_G_3 2 ggddyvtlpd.aslttsafTvsaWvkpdsapqssralvsessgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlr 94 g +dyv++ +sl ++fTv++Wvk++ + ++ ++ s++ + l +d ++++++++++ + v++g +++gq+++++vt++ +g+++ FUN_000430-T1 48 GVTDYVQIWGmRSL--TQFTVCFWVKTTGPKWTAFSYA--SKAASNDLLIDCADSVYLSIGNRG-----VNTGLVINDGQFHQICVTWRnsDGEWK 134 55889998654777..99**********9997554455..777788888888888999888775.....9*******************76688** PP Laminin_G_3 95 lYvnGeevgsstltga.ltkatggply.......iGrdnggdspfdGlidevriynraLsaeei 150 +Y +G +++s+t + + ++g+l+ +G++ + +++++G++ +v++++++L a+ i FUN_000430-T1 135 IYKDGDLAKSGTDLKKgYSVHAAGSLTltqeqdsLGDAFDAKQSLQGMLTNVNVWSYTLPASTI 198 ***********98777645556666651233333666667799999*************99988 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 2.9e-05 0.25 47 123 .. 111 188 .. 94 190 .. 0.78 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.9e-05 Laminin_G_2 47 gkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 g +ndgq+H++ v+++++ + ++ Dg+ +s + ++ + +++ +sl l ++s +a +++++++G l +++v FUN_000430-T1 111 GLVINDGQFHQICVTWRNSDGEWKIykDGDLAKSGTDLKKGYSVHAAGSLTLTQE-QDSLGDAFDAKQSLQGMLTNVNV 188 5568*************88888766558888888887777776666666666665.88899999999999999999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 589 (0.0230573); expected 510.9 (0.02) Passed bias filter: 509 (0.0199256); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2317.46 // Query: FUN_000431-T1 [L=221] Description: FUN_000431 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-32 112.6 0.2 3.1e-32 112.3 0.2 1.0 1 Pentaxin Pentaxin family 2e-12 48.0 1.8 3e-12 47.4 1.8 1.2 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil ------ inclusion threshold ------ 0.018 15.1 0.0 0.025 14.7 0.0 1.2 1 DUF6386 Family of unknown function (DUF6386) 0.12 13.3 0.2 0.18 12.8 0.2 1.2 1 Laminin_G_2 Laminin G domain Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 112.3 0.2 4.9e-36 3.1e-32 3 189 .. 25 208 .. 23 214 .. 0.92 Alignments for each domain: == domain 1 score: 112.3 bits; conditional E-value: 4.9e-36 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fP++ +t+yv++ + L ++t+C++ +t+ fsya k +n+lL + + + l++g+ v + v+ + + + iC++W s+G FUN_000431-T1 25 LEFPNKGVTDYVQIW--GMRSLTQFTVCFWLKTTGP-ISTAFSYASKAASNDLL--NDCANSVYLSIGDLSVNTGVVINDGKFHQICVTWRNSDGQ 115 57**********986..5688***********9844.4567***********98..68889999******************************** PP Pentaxin 99 velwvdGkplvk.kslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrge 189 +++ dG + + ++lk +yt++ + s+ +GqeqDs+G kfd+sqsl G l+++n+W y L ik+++++ ++++ +W + y +rg+ FUN_000431-T1 116 WKIYKDGDLAKEgTGLKIAYTIQVSGSLTQGQEQDSLGDKFDASQSLQGMLTNVNVWSYTLPASTIKEMSRCCLtGKGDVYEWSNFIYGIRGN 208 *******987643899******************************************************9987579*************996 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.4 1.8 4.7e-16 3e-12 2 150 .. 31 181 .. 30 182 .. 0.82 Alignments for each domain: == domain 1 score: 47.4 bits; conditional E-value: 4.7e-16 Laminin_G_3 2 ggddyvtlpd.aslttsafTvsaWvkpdsapqssralvsessgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlr 94 g +dyv++ +sl ++fTv++W+k++ +++ ++ s++ + l d ++++++++++ +v++g +++g++++++vt++ +g+++ FUN_000431-T1 31 GVTDYVQIWGmRSL--TQFTVCFWLKTTGPISTAFSYA--SKAASNDLLNDCANSVYLSIGDL-----SVNTGVVINDGKFHQICVTWRnsDGQWK 117 56888998654777..99***********988554455..88888899999999999999988.....6********************76688** PP Laminin_G_3 95 lYvnGeevgsstltga.ltkatggplyiGrdn.......ggdspfdGlidevriynraLsaeei 150 +Y +G +++++t+ t + +g+l+ G+++ + +++++G++ +v++++++L a+ i FUN_000431-T1 118 IYKDGDLAKEGTGLKIaYTIQVSGSLTQGQEQdslgdkfDASQSLQGMLTNVNVWSYTLPASTI 181 ***********99777444477888887777755543335699999*************99988 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 3.9e-06 0.025 54 118 .. 111 178 .. 75 191 .. 0.82 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 3.9e-06 DUF6386 54 GedGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++++ dla+e + y +sG++ G +d G++++ +s +G+l ++++ sy++ a FUN_000431-T1 111 NSDGQWKIYKDGDLAKEGtglKIAYTIQVSGSLTQGQEQDSLGDKFDASQSLQGMLTNVNVWSYTLPA 178 479*****9999**999833344455568***********************************9755 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.2 2.8e-05 0.18 46 123 .. 93 171 .. 81 173 .. 0.81 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2.8e-05 Laminin_G_2 46 sgkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 +g +ndg++H++ v+++++ + ++ Dg+ ++ + + ++t+++ +sl G ++s ++ +++++++G l +++v FUN_000431-T1 93 TGVVINDGKFHQICVTWRNSDGQWKIykDGDLAKEGTGLKIAYTIQVSGSLTQGQE-QDSLGDKFDASQSLQGMLTNVNV 171 37788*************88888777558888888877777777888888888888.9999999999********99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 482 (0.0188687); expected 510.9 (0.02) Passed bias filter: 407 (0.0159327); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 2272.33 // Query: FUN_000432-T1 [L=224] Description: FUN_000432 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-41 140.7 0.1 7.3e-41 140.5 0.1 1.0 1 Pentaxin Pentaxin family 3.3e-16 60.3 2.1 4.2e-16 59.9 2.1 1.1 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 0.00075 20.4 0.1 0.0011 20.0 0.1 1.2 1 Laminin_G_2 Laminin G domain ------ inclusion threshold ------ 0.036 14.1 0.2 0.19 11.8 0.1 1.9 2 DUF6386 Family of unknown function (DUF6386) 0.18 12.0 0.0 0.27 11.5 0.0 1.2 1 Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor b Domain annotation for each model (and alignments): >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 140.5 0.1 1.4e-44 7.3e-41 3 189 .. 25 211 .. 23 217 .. 0.94 Alignments for each domain: == domain 1 score: 140.5 bits; conditional E-value: 1.4e-44 Pentaxin 3 fvfPkesetsyvkLkaelekPLknltlClrfytdLsrsyslfsyatkkkdnelLifkekdgeyslyvggeevlvkvseeavepvhiCasWesssGi 98 + fPk+ +t+yv++ + L ++t+C++ +t+ s fsya + dnelLi+ ek+g + l vg+ + v+ + + + iC++W s+G FUN_000432-T1 25 LEFPKQGVTDYVHIW--GMRSLTQFTVCFWLKTTQSSIGTPFSYASNAADNELLIYYEKNGRVFLGVGQVVLNTGVVINDGKFHQICVTWRNSDGQ 118 67**********986..5688*************************************************999999999***************** PP Pentaxin 99 velwvdGkplvk.kslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat.lsanildWralnyevrge 189 +++ dG + +lk+gyt++a s+ lGqeqDs+GG+fd++qs+ G l+++n+W y L ik+++++ ++++ +W + y vrg+ FUN_000432-T1 119 WKIYKDGDLARAgAGLKRGYTIHAAGSLTLGQEQDSVGGGFDAKQSFQGMLTNVNVWSYTLPASTIKEMSNCCLtGKGDVYEWSNFIYGVRGN 211 *******87654279*******************************************************9987579************9996 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.9 2.1 8.1e-20 4.2e-16 4 150 .. 33 184 .. 30 185 .. 0.84 Alignments for each domain: == domain 1 score: 59.9 bits; conditional E-value: 8.1e-20 Laminin_G_3 4 ddyvtlpd.aslttsafTvsaWvkpdsapqssralvs.essgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd..ggtlrl 95 +dyv + +sl ++fTv++W+k+++++ ++ + ++ ++++ ++++ +g++++ v+ ++++g +++g++++++vt++ +g++++ FUN_000432-T1 33 TDYVHIWGmRSL--TQFTVCFWLKTTQSSIGTPFSYAsNAADNELLIYYEKNGRVFLGVGQV-----VLNTGVVINDGKFHQICVTWRnsDGQWKI 121 556665433555..89***********9998887444477888******9999999987755.....89*******************76688*** PP Laminin_G_3 96 YvnGeevgsstltga.ltkatggplyiGrdn....gg...dspfdGlidevriynraLsaeei 150 Y +G ++ +++ + t ++g+l++G+++ gg +++f+G++ +v++++++L a+ i FUN_000432-T1 122 YKDGDLARAGAGLKRgYTIHAAGSLTLGQEQdsvgGGfdaKQSFQGMLTNVNVWSYTLPASTI 184 *********999888677799**********988622666******************99988 PP >> Laminin_G_2 Laminin G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 2.1e-07 0.0011 39 123 .. 90 174 .. 77 176 .. 0.86 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 2.1e-07 Laminin_G_2 39 geesllssgkklndgqwHsvsverkgreltlsv..DgqksvssaapgesltlnlesslylGGlpalssekaepvrkgFvGclrdlrv 123 g+++l +g +ndg++H++ v+++++ + ++ Dg+ ++ a ++ +t+++ +sl lG ++s +++++F+G l +++v FUN_000432-T1 90 GQVVLN-TGVVINDGKFHQICVTWRNSDGQWKIykDGDLARAGAGLKRGYTIHAAGSLTLGQE-QDSVGGGFDAKQSFQGMLTNVNV 174 444444.49999*************88887666559999999999999999***********9.99999***************986 PP >> DUF6386 Family of unknown function (DUF6386) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.13 6.8e+02 72 91 .. 74 93 .. 65 111 .. 0.73 2 ? 11.8 0.1 3.6e-05 0.19 55 118 .. 115 181 .. 98 193 .. 0.81 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.13 DUF6386 72 evlylrvpsGkvfvGagedv 91 e+l + G+vf+G g+ v FUN_000432-T1 74 ELLIYYEKNGRVFLGVGQVV 93 44445567899999999866 PP == domain 2 score: 11.8 bits; conditional E-value: 3.6e-05 DUF6386 55 edGvyevelvddlaees...evlylrvpsGkvfvGagedvtGgdlePdesdsGvlielepGsyevka 118 dG++++ dla+ + y ++G++ +G +d Gg+++ +s +G+l ++++ sy++ a FUN_000432-T1 115 SDGQWKIYKDGDLARAGaglKRGYTIHAAGSLTLGQEQDSVGGGFDAKQSFQGMLTNVNVWSYTLPA 181 68888888888888776333455788899**********************************9755 PP >> Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 5.2e-05 0.27 51 137 .. 44 128 .. 22 142 .. 0.77 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 5.2e-05 Toxin_R_bind_N 51 tnnFsisfWlripkkdnseskiIsskknns..GWkvslenneliftlidsngnekkivlsdyinkWvfitisndrlknklliyingklv 137 F+++fWl++++ + s +n++ ++ e+n+ +f + +v++ + k + i ++ + + +iy +g l FUN_000432-T1 44 LTQFTVCFWLKTTQSSIGT--PFSYASNAAdnELLIYYEKNGRVFLGVGQVVLNTGVVIN--DGKFHQICVTWRNSDGQWKIYKDGDLA 128 578***********99983..333333333114678889999999888888888888888..678889999988888888999888775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 465 (0.0182032); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2241.85 // Query: FUN_000433-T1 [L=537] Description: FUN_000433 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-39 135.2 0.2 6.5e-39 134.1 0.0 1.7 2 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 4.3e-34 119.3 0.2 6e-34 118.8 0.2 1.2 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.093 12.9 0.0 0.2 11.8 0.0 1.5 1 Cytochrom_NNT NapC/NirT cytochrome c family, N-terminal reg 0.18 12.1 0.4 0.32 11.3 0.4 1.4 1 FAM176 FAM176 family Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 134.1 0.0 1e-42 6.5e-39 2 216 .] 86 291 .. 85 291 .. 0.83 2 ? -2.6 0.0 0.65 4.1e+03 22 47 .. 412 437 .. 403 450 .. 0.73 Alignments for each domain: == domain 1 score: 134.1 bits; conditional E-value: 1e-42 Neur_chan_LBD 2 erlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpse...kiWlPdivlyn.ka 93 +rll+ ++++Ydk++rP+ e k ++V+++l + ++ +++e+++e+++++++ q W+D+rL + +s+ l+ + k+W+Pd++++n FUN_000433-T1 86 SRLLDAVFKNYDKRIRPF-YEVKSLKVDMDLLILSFGELSETQMEFSVDLYMGQFWQDPRLGFGI-----NQSIILSGDateKLWVPDTFIINsID 175 699**************9.88888***************************************63.....345666666777***********555 PP Neur_chan_LBD 94 dgehevtekntnvrvs.sdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelvev.e 187 +++h+ + n+++ ++ ++Gt++++++ + +ssC++d++ +P+D+q C+l feS+++++++v+l w+k +++ + +e++ ++ + FUN_000433-T1 176 TKIHKLVSINKKAWIHlQNGTIMLVLRFTARSSCKVDLRDYPLDDQICHLAFESFSFEEKDVNLTWRKPL------GTNIHIY--DKEMAQFDIlT 263 5678888899999998569************************************************932......2222222..22333333303 PP Neur_chan_LBD 188 akreekktgsyselsysdvtftltlrRkp 216 a+r+ k + y + ++ vt+t+++rR++ FUN_000433-T1 264 ARRHGK-HPTYHSDPFAGVTATIHFRRRT 291 455555.6667777799**********96 PP == domain 2 score: -2.6 bits; conditional E-value: 0.65 Neur_chan_LBD 22 eskpvtVslelslsqiisvdeknqel 47 e+ +vtVs++ +++ + +++ek+++ FUN_000433-T1 412 EKMTVTVSIGNKTYDFNKYKEKTEKT 437 44567777777888888888777665 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 118.8 0.2 9.4e-38 6e-34 1 233 [] 298 520 .. 298 520 .. 0.65 Alignments for each domain: == domain 1 score: 118.8 bits; conditional E-value: 9.4e-38 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 ++iPc+ +viLs+++F++++ + +v LgI ++Lt + + +++ +P++S+ ++++ +Ll +vfvf+ l+e+v Vl + r++++ k++++ FUN_000433-T1 298 MYIPCICVVILSWVSFWIDETDGSDRVGLGIATVLTISFMQGALNDNVPRVSYLKSVDY-FLLGSFVFVFMTLIEYVLVLKQS-RKERKWKKERE 390 6**********************************************************.*********************97.77777777777 PP Neur_chan_memb 96 vrklfleklpr.lllmkrpkeeeeeeassagssskae.elilkksrselkaekqsersglerettestessegkelkqs..eelspelekaveev 186 +++l e+ + +l+m ++e+ s g+++ ++ k +++el + s+ s++er+ ++ s+ ++++++ ++ ++l++ + + FUN_000433-T1 391 KKTLERERKREaVLMMADSDDEKMTVTVSIGNKTYDFnKYKEKTEKTELLPC--SNHSNSERAVRIMEPMSNVSDNSKPtdRSQLKKLQRRPSMI 483 7777666655505555554444444443333333332022222233332222..22222223322222222222222222233333345444444 PP Neur_chan_memb 187 nfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 ++i+k+ ++ e++ +D++s+i+fp+ + ++ ++f FUN_000433-T1 484 QMIRKT----IEDGEEEI------CYLDKYSRIVFPVSYTIFLGIYF 520 444444....44444444......35**************9977776 PP >> Cytochrom_NNT NapC/NirT cytochrome c family, N-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 3.2e-05 0.2 41 78 .. 9 46 .. 4 53 .. 0.89 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 3.2e-05 Cytochrom_NNT 41 sCHemednyeeykesvHyknrsGvraeCadCHvPkelv 78 s He +n +ey+++ H++n++ +r ++C v k ++ FUN_000433-T1 9 SLHETLKNNSEYQQDLHFRNKKVIRSINPNCNVTKMIL 46 569999*************************9988655 PP >> FAM176 FAM176 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.4 5e-05 0.32 25 122 .. 356 454 .. 352 484 .. 0.67 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 5e-05 FAM176 25 yFvlgvcvGLvltLc..llViriscrkdlkklakkkkelkeeseed....eedseeeeeeeeedsseseikdeltel.ekssefertlsvnvftsa 113 yF+lg v +++tL+ +lV++ s +++ k++++kk+l++e++++ + +++e+ +++ +i +++ + + ++++e+t + ++ FUN_000433-T1 356 YFLLGSFVFVFMTLIeyVLVLKQSRKERKWKKEREKKTLERERKREavlmM----AD-SDDEKMTVTVSIGNKTYDFnKYKEKTEKT-ELLPCSNH 445 8999999999****8335666666666666777888888777777744332....33.22334444444444444443444445555.55555566 PP FAM176 114 eelerAqRl 122 + erA R+ FUN_000433-T1 446 SNSERAVRI 454 666666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (537 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1893 (0.0741045); expected 510.9 (0.02) Passed bias filter: 1043 (0.0408299); expected 510.9 (0.02) Passed Vit filter: 105 (0.00411039); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 5244.85 // Query: FUN_000436-T1 [L=165] Description: FUN_000436 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0014 19.1 0.2 0.0026 18.3 0.2 1.3 1 Microp_apicomplexa_20 Apicomplexa microprotein Domain annotation for each model (and alignments): >> Microp_apicomplexa_20 Apicomplexa microprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.2 1e-07 0.0026 3 56 .. 71 126 .. 69 128 .. 0.87 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1e-07 Microp_apicomplexa_20 3 lviGLvgaL.Ggvveavkevle..krsilsGkLkgaLekvievvlevvkkLvegvkk 56 viG v +L G ++a+k+ ++ r+il+G + + ++ ++l+vv+kL e+v+ FUN_000436-T1 71 SVIGTVSSLvGFAIDAGKQLMKafVRAILLG-VEELWKAILSIILQVVDKLNETVQH 126 58999999846689*******9888*****9.67888999**************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (165 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1909 (0.0747309); expected 510.9 (0.02) Passed bias filter: 918 (0.0359366); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1651.09 // Query: FUN_000437-T1 [L=703] Description: FUN_000437 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-58 199.4 16.8 2.5e-44 152.2 6.5 2.4 2 Beta-prop_WDR5 WDR5 beta-propeller domain 6.4e-54 182.9 12.6 2.1e-28 99.7 6.3 3.2 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 6.4e-45 150.2 30.8 6e-08 33.4 0.4 7.6 7 WD40 WD domain, G-beta repeat 1.1e-42 146.5 18.8 1e-17 64.6 2.0 4.5 5 Beta-prop_THOC3 THOC3 beta-propeller domain 2.9e-39 135.3 1.5 1.1e-13 51.3 0.1 3.2 3 WD40_Prp19 Prp19 WD40 domain 5.7e-33 114.9 11.2 1.5e-13 51.1 1.9 3.1 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 1.2e-31 110.5 7.7 2.6e-09 37.1 0.2 4.2 4 WD40_WDHD1_1st WDHD1 first WD40 domain 3.4e-28 99.3 10.3 5.2e-19 69.1 2.7 2.2 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 2.1e-27 96.4 17.9 4.1e-15 56.1 8.8 3.3 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 2.3e-27 96.4 12.0 5.7e-19 68.9 5.4 4.5 2 EIF3I EIF3I 9.3e-26 91.1 11.8 4e-10 39.7 0.3 3.2 3 WD40_Gbeta G protein beta WD-40 repeat protei 1.4e-19 70.3 16.3 0.0015 19.0 0.0 6.8 6 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 7.3e-19 68.7 7.5 3.4e-08 33.6 0.5 3.5 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 8.6e-19 68.2 7.9 1.7e-11 44.2 4.6 2.7 2 WDR55 WDR55 1.3e-17 64.3 10.6 1.1e-08 34.9 1.4 3.8 3 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 6.4e-17 62.3 8.1 0.00019 21.3 0.1 5.1 5 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 1.4e-15 57.6 21.1 6.9e-05 22.3 10.0 3.4 3 Beta-prop_SCAP SCAP Beta-propeller 1.5e-14 54.3 8.5 9e-07 28.7 0.1 3.4 3 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 2.2e-14 54.0 4.4 3e-10 40.5 1.2 2.9 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 6e-13 49.2 6.7 1.2e-06 28.5 2.2 5.3 3 Beta-prop_EML_2 Echinoderm microtubule-associated 1.5e-12 47.5 10.2 1.9e-06 27.4 0.9 3.5 3 Beta-prop_WDR41 WDR41 1.7e-12 47.3 2.0 5.5e-12 45.8 2.0 1.9 1 F-box-like F-box-like 1.2e-11 44.6 3.1 2e-05 24.1 0.1 3.9 4 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 4.8e-11 42.9 5.5 0.00026 20.8 1.0 4.3 6 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 4e-10 40.1 10.1 0.00024 21.2 4.0 3.3 3 Beta-prop_EML Echinoderm microtubule-associated 4.1e-09 36.3 1.6 0.031 13.6 0.0 4.6 5 Beta-prop_SPT8 SPT8 beta propeller 1.2e-08 34.8 5.4 0.0056 16.1 0.6 3.6 4 Beta-prop_IFT122_1st IFT122 first beta-propeller 1.2e-07 32.0 4.7 0.0081 16.1 0.8 3.5 3 Beta-prop_EIPR1 EIPR1 beta-propeller 1.2e-07 31.8 0.8 1.2e-07 31.8 0.8 2.1 1 F-box F-box domain 5.6e-07 29.2 13.0 0.012 14.9 0.6 4.4 5 NBCH_WD40 Neurobeachin beta propeller domain 5.6e-07 29.7 2.7 0.016 15.1 0.0 5.0 5 Beta-prop_RIG_2nd RIG second beta-propeller 9.6e-07 29.5 3.0 0.041 14.7 0.2 2.7 2 DUF4508 Domain of unknown function (DUF450 9e-06 25.3 9.9 0.0076 15.7 0.1 5.0 5 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 1.8e-05 25.4 3.3 17 6.2 0.0 5.2 4 ANAPC4_WD40 Anaphase-promoting complex subunit 6.1e-05 22.4 14.3 0.53 9.4 0.1 5.1 4 Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-prope 0.00061 19.0 3.3 0.14 11.2 0.6 2.8 2 Beta-prop_WDR11_2nd WDR11 second beta-propeller 0.0038 17.1 3.8 0.4 10.4 0.3 4.1 4 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 ------ inclusion threshold ------ 0.029 14.7 0.0 51 4.0 0.0 3.2 3 CNH CNH domain 0.045 13.3 1.3 0.45 10.0 0.4 2.4 2 Beta-prop_NOL10_N Nucleolar protein 10-like, N-termi 0.43 10.0 2.5 6.4 6.1 0.3 3.0 3 Beta-prop_VPS8 Vps8 beta-propeller Domain annotation for each model (and alignments): >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.2 6.5 3.9e-47 2.5e-44 18 232 .. 430 640 .. 415 644 .. 0.93 2 ! 61.4 2.6 1.7e-19 1.1e-16 71 162 .. 606 702 .. 605 703 .] 0.87 Alignments for each domain: == domain 1 score: 152.2 bits; conditional E-value: 3.9e-47 Beta-prop_WDR5 18 gkllasasaDktikiwdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSGsfDe 112 +++a+ s D+tik+wd+++g+l++t++gh++Gi ++ + s+s +++s+S Dkt+r+w+++t+ + ++l gH v ++ + k+++l+SGs D+ FUN_000437-T1 430 KNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKS-IIISGSYDKTIRLWSLRTKACARILMGHDGPVWAI--ERKEDILISGSSDK 521 579**************************************99.99******************************988..5899********** PP Beta-prop_WDR5 113 tvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvsfvkFspngkyiLastldstirLwdyeke 207 t +lW++r+ k+l +l +H+ v +vd++ + + s+s D ++r+wd+++g cl ++ +++ +++ + s + y+ + + ++ Lw+++++ FUN_000437-T1 522 TAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQSTDCTVTTVSYDHGYVAVGS-GTMVSLWNLTTG 615 **********************************************************999999999999999****98776.689********* PP Beta-prop_WDR5 208 kvvktYkghknekycisaefsetgg 232 +v +++ghkn+ c++ +f++ +g FUN_000437-T1 616 DCVHEFSGHKNRVECVKLKFMMVNG 640 ********************97655 PP == domain 2 score: 61.4 bits; conditional E-value: 1.7e-19 Beta-prop_WDR5 71 tvriwdvetgkllktlkgHtnyvfcvaF.......npkgnllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliri 158 +v +w+++tg ++++++gH+n v cv+ +++ l+vS++ D ++ Wd+++++c++tl +H d v +++ d+t i+s s+D +r+ FUN_000437-T1 606 MVSLWNLTTGDCVHEFSGHKNRVECVKLkfmmvngKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHV--DSTRIISVSFDHRVRV 698 699**********************9751133322346679********************************9975..799************* PP Beta-prop_WDR5 159 wdte 162 w+ + FUN_000437-T1 699 WNFN 702 *976 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 89.1 0.6 6e-28 3.8e-25 65 184 .] 414 528 .. 404 528 .. 0.91 2 ! 99.7 6.3 3.3e-31 2.1e-28 13 183 .. 525 700 .. 525 701 .. 0.87 Alignments for each domain: == domain 1 score: 89.1 bits; conditional E-value: 6e-28 Beta-prop_WDR3_1st 65 vtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghr 155 + + gHk++v +++ ++ +a+Gs D +i vwD +++ + ++ gH+ ++s++fl++ ++++s+S D++i+lW l+t+ c + l+gh+ FUN_000437-T1 414 MDMVGHKNNVLTVCG--YKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSK-SIIISGSYDKTIRLWSLRTKACARILMGHD 501 5689******99884..5689*************************************97.7***************************** PP Beta-prop_WDR3_1st 156 sevwslalskdekllvtgssdselrvwki 184 + vw+++ ++e++l++gssd++ ++w+i FUN_000437-T1 502 GPVWAIE--RKEDILISGSSDKTAKLWNI 528 ****977..5678**************97 PP == domain 2 score: 99.7 bits; conditional E-value: 3.3e-31 Beta-prop_WDR3_1st 13 vWdlkkgekvatlegeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHks...avtalafdkdgsrLasGskDtdiivwDv 100 +W++++ + +++l g++ v ++ ++ k+ +G+ d ++r+wd++sg + +fn +s +vt++++d+ +a Gs t + +w++ FUN_000437-T1 525 LWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQStdcTVTTVSYDH--GYVAVGS-GTMVSLWNL 612 6*******************************************************8877333477777766..6666665.589****** PP Beta-prop_WDR3_1st 101 vaeaglfrLkgHkdqvtsvaf..l.....eekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtgssdselrvwk 183 +++ +++ ++gHk++v v++ + +e ++vss+kD lik Wd+e+ +c++tl ghr +v s+++++ +++++ s d+++rvw+ FUN_000437-T1 613 TTGDCVHEFSGHKNRVECVKLkfMmvngkKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDS--TRIISVSFDHRVRVWN 700 ****************977542253333336689*********************************99975..8**************7 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.1 8.1e-08 5.2e-05 6 39 .] 415 446 .. 410 446 .. 0.89 2 ! 33.4 0.4 9.4e-11 6e-08 1 39 [] 450 487 .. 450 487 .. 0.92 3 ! 22.5 0.0 2.6e-07 0.00017 3 39 .] 493 527 .. 491 527 .. 0.92 4 ! 30.1 1.3 1e-09 6.7e-07 2 39 .] 532 569 .. 531 569 .. 0.94 5 ? 6.7 1.3 0.027 17 9 39 .] 582 611 .. 573 611 .. 0.75 6 ! 20.5 0.0 1.1e-06 0.0007 1 39 [] 615 660 .. 615 660 .. 0.85 7 ! 30.1 0.8 1.1e-09 6.8e-07 2 39 .] 665 700 .. 664 700 .. 0.97 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 8.1e-08 WD40 6 tlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 + gH+++V ++ + +++a+gs D+t+k+Wd FUN_000437-T1 415 DMVGHKNNVLTV--CGYKNFIATGSLDRTIKVWD 446 567**999****..9999***************9 PP == domain 2 score: 33.4 bits; conditional E-value: 9.4e-11 WD40 1 gkllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 g+l++t++gHt g++s++f + + ++ sgs+D+t++lW+ FUN_000437-T1 450 GTLIQTFTGHTRGIWSIRFLSKSIII-SGSYDKTIRLWS 487 6789*************999999887.9**********6 PP == domain 3 score: 22.5 bits; conditional E-value: 2.6e-07 WD40 3 llrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 + r+l gH+++V+++ ++l+sgs D+t klW+ FUN_000437-T1 493 CARILMGHDGPVWAI--ERKEDILISGSSDKTAKLWN 527 78999***999**99..999999****99*******7 PP == domain 4 score: 30.1 bits; conditional E-value: 1e-09 WD40 2 kllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 kll +l gH++ V +++ +++ + +sgs D+tv++Wd FUN_000437-T1 532 KLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWD 569 78999****888*************************9 PP == domain 5 score: 6.7 bits; conditional E-value: 0.027 WD40 9 gHtsg..VtslafspdgsllasgsdDgtvklWd 39 g +++ Vt++ s d+ ++a+gs v lW+ FUN_000437-T1 582 GQSTDctVTTV--SYDHGYVAVGS-GTMVSLWN 611 44233369999..***********.*******7 PP == domain 6 score: 20.5 bits; conditional E-value: 1.1e-06 WD40 1 gkllrtlkgHtsgVtsla...fspdgsl....lasgsdDgtvklWd 39 g ++++++gH++ V +++ +g+ ++s+++Dg +k Wd FUN_000437-T1 615 GDCVHEFSGHKNRVECVKlkfMMVNGKKeaglIVSSGKDGLIKYWD 660 68********999****76665555555999899***********9 PP == domain 7 score: 30.1 bits; conditional E-value: 1.1e-09 WD40 2 kllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++++tl+gH+++V+s+ + d++ ++s s D++v++W+ FUN_000437-T1 665 SCIQTLRGHRDNVNSI--HVDSTRIISVSFDHRVRVWN 700 79*******999****..*******************7 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 0.1 3.6e-10 2.3e-07 164 223 .. 413 470 .. 402 475 .. 0.86 2 ! 28.9 0.1 1.2e-09 7.6e-07 164 220 .. 453 508 .. 453 512 .. 0.91 3 ! 35.4 0.1 1.2e-11 7.8e-09 16 80 .. 473 532 .. 469 534 .. 0.90 4 ! 64.6 2.0 1.6e-20 1e-17 139 260 .. 509 631 .. 507 634 .. 0.90 5 ! 29.6 0.3 7.4e-10 4.7e-07 16 77 .. 646 702 .. 638 703 .] 0.82 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 3.6e-10 Beta-prop_THOC3 164 vktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvsFSh 223 v + +h++n+l+v ++++A+Gs D ++++WD+++++ ++t+t+++ ++s++F + FUN_000437-T1 413 VMDMVGHKNNVLTV--CGYKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLS 470 66788999999888..456789***********************************955 PP == domain 2 score: 28.9 bits; conditional E-value: 1.2e-09 Beta-prop_THOC3 164 vktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvs 220 ++t+++ht+ ++++ f + ++ +Gs+D++++lW l++ +c r l +++ pv++++ FUN_000437-T1 453 IQTFTGHTRGIWSIRFLS-KSIIISGSYDKTIRLWSLRTKACARILMGHDGPVWAIE 508 5899************65.67899*****************************9985 PP == domain 3 score: 35.4 bits; conditional E-value: 1.2e-11 Beta-prop_THOC3 16 rLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgk 80 + sgs+Dkt+r+w+l+++++++ l gh++ V +++ + +d+l+++ssDkt +lW++r+ k FUN_000437-T1 473 IIISGSYDKTIRLWSLRTKACAR--ILMGHDGPVWAIERK---EDILISGSSDKTAKLWNIRQCK 532 678***************99987..69********99874...689****************966 PP == domain 4 score: 64.6 bits; conditional E-value: 1.6e-20 Beta-prop_THOC3 139 pdgkllllttgdgtvevlsypsleevktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlesp.vrsvsFShdGkllAsa 231 +++++l+++++d+t +++++ +++ + +l +h++ ++cv++d + + +Gs D +v++WD++++icl++++ +s ++ S+d ++A++ FUN_000437-T1 509 RKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQSTdCTVTTVSYDHGYVAVG 602 67899******************************************************************976554277778999******99 PP Beta-prop_THOC3 232 sedktidiasvetgesvhtiktea.avnsv 260 s +++++++++tg++vh+++ ++ +v++v FUN_000437-T1 603 S-GTMVSLWNLTTGDCVHEFSGHKnRVECV 631 7.59****************9875256665 PP == domain 5 score: 29.6 bits; conditional E-value: 7.4e-10 Beta-prop_THOC3 16 rLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvr 77 ++s+++D ++ w++e+ ++ + +l+gh d+V+++ ++ t +++++s D++vr+W+ + FUN_000437-T1 646 LIVSSGKDGLIKYWDIEQASCIQ--TLRGHRDNVNSIHVDST---RIISVSFDHRVRVWNFN 702 47899999999999999888775..89999999999999865...68999999999999875 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.5 0.0 3.3e-16 2.1e-13 14 97 .. 426 507 .. 419 510 .. 0.92 2 ! 51.3 0.1 1.8e-16 1.1e-13 58 184 .. 508 632 .. 505 637 .. 0.86 3 ! 31.9 0.1 1.5e-10 9.7e-08 17 78 .. 642 701 .. 635 703 .] 0.89 Alignments for each domain: == domain 1 score: 50.5 bits; conditional E-value: 3.3e-16 WD40_Prp19 14 lnpsdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtsl 97 ++ kn ++tG D+++ ++d+++++ ++t++ght+ + +++f s+++++s+s Dkt+r+w+ k +a +l h++ v ++ FUN_000437-T1 426 VCG-YKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFL-SKSIIISGSYDKTIRLWSLRTKACARILMGHDGPVWAI 507 553.479*************************************9.779******************************99776 PP == domain 2 score: 51.3 bits; conditional E-value: 1.8e-16 WD40_Prp19 58 hpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgdylvsaskDgtwalhdletgktllkvkdeeskeaitsaqfHPDGlllgtG 153 +ed+l+s+s+Dkt+++w+ + + l h++ v ++++ t + + s+s D+t+ ++d+++g +l +++ +s ++ t + D +++G FUN_000437-T1 508 ERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQS-TDCTVTTVSYDHGYVAVG 602 568899***************99999999****************************************99986554.455566666666667788 PP WD40_Prp19 154 tkdgtvkiWDiksqknvasleghsgavtsla 184 + +v++W++ ++++v +++gh+++v++++ FUN_000437-T1 603 S-GTMVSLWNLTTGDCVHEFSGHKNRVECVK 632 7.479*******************9998765 PP == domain 3 score: 31.9 bits; conditional E-value: 1.5e-10 WD40_Prp19 17 sdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkk 78 ++ l++++G+D+ + ++d e+ + ++tl+gh+ +v+++ + ++ ++s s D++vrvw+ FUN_000437-T1 642 KEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVD--STRIISVSFDHRVRVWNF 701 45569*********************************9987..5679************96 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.1 8.1e-07 0.00052 169 228 .. 414 471 .. 406 472 .. 0.71 2 ! 49.8 0.4 6e-16 3.8e-13 188 289 .. 472 571 .. 469 575 .. 0.95 3 ! 51.1 1.9 2.4e-16 1.5e-13 180 287 .. 589 700 .. 573 703 .] 0.85 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 8.1e-07 Beta-prop_WDR3_2nd 169 lslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpk 228 +++ Ghk vl+ + ++i+tgs D++ik+w + G + +++++h+ + s++f +k FUN_000437-T1 414 MDMVGHKNNVLT--VCGYKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSK 471 556677776654..4566677888888888888888888888888888888888877665 PP == domain 2 score: 49.8 bits; conditional E-value: 6e-16 Beta-prop_WDR3_2nd 188 klivtgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkvkyWDadkfekiqtleghagevwalavsskgkfvvsas 278 ++i++gs Dk+i++w l c + l++hd v +++ +k l+s + dk+ k W+ + + + +l gh+g v ++ + ++ k s+s FUN_000437-T1 472 SIIISGSYDKTIRLWSLRTKACARILMGHDGPVWAIE--RKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGS 560 79*******************************9885..78899*********************************************** PP Beta-prop_WDR3_2nd 279 hDksiRlwert 289 D+++R+w+ + FUN_000437-T1 561 GDRTVRVWDVS 571 ********865 PP == domain 3 score: 51.1 bits; conditional E-value: 2.4e-16 Beta-prop_WDR3_2nd 180 sldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvp.......ktHylfsagkdkkvkyWDadkfekiqtleghagevw 263 +s+D ++ gs + + +w l GDc + + +h++ v v++ ++ + s+gkd+ +kyWD ++ ++iqtl+gh+++v FUN_000437-T1 589 VTTVSYDHGYVAVGSG-TMVSLWNLTTGDCVHEFSGHKNRVECVKLKFmmvngkkEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVN 678 5678999999888885.78********************99766543322555547789******************************** PP Beta-prop_WDR3_2nd 264 alavsskgkfvvsashDksiRlwe 287 ++ v s + ++s+s D+ +R+w+ FUN_000437-T1 679 SIHVDS--TRIISVSFDHRVRVWN 700 *99975..589************7 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.0 0.0 8.9e-12 5.7e-09 97 166 .. 429 497 .. 418 503 .. 0.91 2 ! 37.1 0.2 4.1e-12 2.6e-09 93 171 .. 506 584 .. 495 590 .. 0.92 3 ! 30.1 0.1 5.7e-10 3.6e-07 88 166 .. 586 670 .. 583 671 .. 0.84 4 ! 25.4 0.2 1.6e-08 1e-05 101 158 .. 647 702 .. 646 703 .] 0.94 Alignments for each domain: == domain 1 score: 36.0 bits; conditional E-value: 8.9e-12 WD40_WDHD1_1st 97 dgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktl 166 ++++a gs D tikv + ++++ + t++gh+ + s+++ +k+ +++S s D t+++W++++k c++ l FUN_000437-T1 429 YKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKS-IIISGSYDKTIRLWSLRTKACARIL 497 5789*************************************876.99******************98765 PP == domain 2 score: 37.1 bits; conditional E-value: 4.1e-12 WD40_WDHD1_1st 93 alskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlpk 171 a+++++ +l++gs+D t k+ ++++ + ++l gh++ v +v+ld + + S s+D tv++Wd++s+ c+++++v ++ FUN_000437-T1 506 AIERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQS 584 46678999****************************************************************9998654 PP == domain 3 score: 30.1 bits; conditional E-value: 5.7e-10 WD40_WDHD1_1st 88 pvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkg.......eylaSsscDGtvkiWdieskecvktl 166 ++t ++s d+ ++a+gs +++ + ++++++ +++++ghk+ v +v+l+ + +++Ss+ DG +k+Wdie+ +c++tl FUN_000437-T1 586 DCTVTTVSYDHGYVAVGSG-TMVSLWNLTTGDCVHEFSGHKNRVECVKLKFMMvngkkeaGLIVSSGKDGLIKYWDIEQASCIQTL 670 5677788889999*99997.679************************997443333333389********************9986 PP == domain 4 score: 25.4 bits; conditional E-value: 1.6e-08 WD40_WDHD1_1st 101 laagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdie 158 ++++++D ik ++e+ s + tl+gh + v s+ +d+++ ++S s D v++W+++ FUN_000437-T1 647 IVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDSTR--IISVSFDHRVRVWNFN 702 78999********************************887..9************986 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.1 2.7 8.1e-22 5.2e-19 58 222 .. 425 583 .. 404 594 .. 0.86 2 ! 34.4 1.4 3.2e-11 2e-08 19 119 .. 595 700 .. 584 703 .] 0.58 Alignments for each domain: == domain 1 score: 69.1 bits; conditional E-value: 8.1e-22 WD40_CDC20-Fz 58 kwsedgelLavGtssgevelwdvekkkklrtleghssrvgalaw.nenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrllAs 152 + ++++a+G+ + ++++wd+++++ ++t++gh+ + ++++ ++++++sGs d++i+ + +rtk ++++l +h + v ++ ++d l s FUN_000437-T1 425 TVCGYKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFlSKSIIISGSYDKTIRLWSLRTKA--CARILMGHDGPVWAIERKED--ILIS 516 3344568*************************************67789******************7..6799********98876655..9*** PP WD40_CDC20-Fz 153 GgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgs 222 G++d+t k+w++r+++ l++l h+ v +++ + k +G+G D+t+r+w++++g +l+s+++g+ FUN_000437-T1 517 GSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAF-SGSG--DRTVRVWDVSSGICLSSFNVGQ 583 *********************************99888775.5555..*****************99875 PP == domain 2 score: 34.4 bits; conditional E-value: 3.2e-11 WD40_CDC20-Fz 19 kknvlavalgssvylwnaetgevkelldlseesdyvtsvkws.......edgelLavGtssgevelwdvekkkklrtleghssrvgalawnenlls 107 +++++av+ g++v lwn +tg++ + +s +++ v +vk + ++ l++ ++g ++ wd+e+ ++++tl+gh+++v+++ ++++ ++ FUN_000437-T1 595 DHGYVAVGSGTMVSLWNLTTGDCVHE--FSGHKNRVECVKLKfmmvngkKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDSTRII 688 34677777777777777777766543..33344444444332223333233445555666777777777777777777777777777777777777 PP WD40_CDC20-Fz 108 sGsrdgkilhhD 119 s s d+++++++ FUN_000437-T1 689 SVSFDHRVRVWN 700 777666666554 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.1 0.00012 0.076 135 182 .. 419 465 .. 411 467 .. 0.75 2 ! 56.1 8.8 6.5e-18 4.1e-15 2 183 .. 464 631 .. 463 639 .. 0.91 3 ! 33.2 0.4 6.3e-11 4e-08 147 204 .. 644 701 .. 637 703 .] 0.95 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.00012 Beta-prop_TEP1_2nd 135 hrdWv.tgcaWtkddllvscssdGsvglWdiekeqrlgkflGhqsavsa 182 h++ v t c + + ++ ++s d ++ +Wd ++++ +++f+Gh + + FUN_000437-T1 419 HKNNVlTVCGYKN--FIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWS 465 5543326777654..8888999999999999999999999999887765 PP == domain 2 score: 56.1 bits; conditional E-value: 6.5e-18 Beta-prop_TEP1_2nd 2 salvWlsdkvlvsGaedgslqvWkleesssqcllllkahqkavlglalsqkllasasedltvrlWskelltqpekaeslsslsvlrghtga 92 +++ +ls+++++sG+ d +++ W+l++ ++c +l++h+++v+++ +++l s s d t +lW+ + + l l gh+g FUN_000437-T1 464 WSIRFLSKSIIISGSYDKTIRLWSLRT--KACARILMGHDGPVWAIERKEDILISGSSDKTAKLWNIRQC---------KLLFSLVGHNGC 543 78999*******************976..579999******************************87655.........457889****** PP Beta-prop_TEP1_2nd 93 vtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkddllvscssdGsvglWdiekeqrlgkflGhqsavsav 183 v c + ++ +g+ dr++ +Wdv+ + + s+ t + d+ v+ s v+lW++++++ +++f Gh++ v +v FUN_000437-T1 544 VFCVDLDDTCKRAFSGSGDRTVRVWDVSS---GICLSSFNVGQSTDCTVTTVSYDHGYVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECV 631 ***************************98...789999999988888888888888999999999*********************99877 PP == domain 3 score: 33.2 bits; conditional E-value: 6.3e-11 Beta-prop_TEP1_2nd 147 ddllvscssdGsvglWdiekeqrlgkflGhqsavsavvaveehvvsvgrdGllkvWdl 204 +l+vs+ +dG + Wdie+ ++++ Gh+ v ++ + +++sv+ d ++vW+ FUN_000437-T1 644 AGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDSTRIISVSFDHRVRVWNF 701 5799****************************************************96 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.4 8.8e-09 5.6e-06 24 86 .. 432 493 .. 412 498 .. 0.86 2 ! 68.9 5.4 8.9e-22 5.7e-19 6 215 .. 497 699 .. 495 702 .. 0.82 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 8.8e-09 EIF3I 24 llfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGke 86 ++ + + d+++ vw ++ G + t++Gh+ +wsi s++ +++gs d+t++lW+++t + FUN_000437-T1 432 FIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKS-IIISGSYDKTIRLWSLRTKAC 493 6778899*****************************98776.789************998766 PP == domain 2 score: 68.9 bits; conditional E-value: 8.9e-22 EIF3I 6 lkGheRaltqikynreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletktav..rsv 99 l+Gh+ ++ i +r+ D+l+s + dk+a +w l ++ Gh+G v+++d+d +++++ +gs+d tv++Wdv++G +l+++++ + FUN_000437-T1 497 LMGHDGPVWAI--ERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQSTdcTVT 590 78999999887..5899*******************************************************************998655410444 PP EIF3I 100 efsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghedgeiskydlktgeklksvkehekqitdlq 195 + s++ ++v + +m + +++ d+ +e + + ++e+ + k++++ +++ i+++ +dg i+ +d+++ +++++ + h+++++ ++ FUN_000437-T1 591 TVSYDH-GYVAVGSGTMVSLWNLTTGDCVHEF----SGHKNRVECVKLKFMMVNGKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIH 681 445544.4555666677777777777765433....2333456666778888888899999********************************987 PP EIF3I 196 lskdktylitaskDktakll 215 + d+t +i+ s D+ +++ FUN_000437-T1 682 V--DSTRIISVSFDHRVRVW 699 6..77889999999887776 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.7 0.3 6.3e-13 4e-10 130 232 .. 408 507 .. 398 510 .. 0.85 2 ! 28.6 2.0 1.4e-09 9.2e-07 156 231 .. 513 589 .. 508 603 .. 0.85 3 ! 29.0 0.2 1.2e-09 7.4e-07 157 234 .. 598 682 .. 588 702 .. 0.76 Alignments for each domain: == domain 1 score: 39.7 bits; conditional E-value: 6.3e-13 WD40_Gbeta 130 egnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfigh 225 +g +v + + l++c + n i t s d t +wd +tg +f+ght + s+ + +++sg+ d +++lw +r c + ++gh FUN_000437-T1 408 NGRCKVMDMVGHKNNVLTVCGY--KNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLS-KSIIISGSYDKTIRLWSLRTKACARILMGH 500 4556666555555678899987..689*********************************99875.5789************************** PP WD40_Gbeta 226 esdinai 232 + + ai FUN_000437-T1 501 DGPVWAI 507 9988776 PP == domain 2 score: 28.6 bits; conditional E-value: 1.4e-09 WD40_Gbeta 156 qivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtf.ighesdina 231 +++ s d t+ lw+i + ++vgh+g v+ + l + sg+ d ++++wdv g+c +f +g+ +d FUN_000437-T1 513 ILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFnVGQSTDCTV 589 4678899*********************************************************9994466666544 PP == domain 3 score: 29.0 bits; conditional E-value: 1.2e-09 WD40_Gbeta 157 ivtssgdttcalwdietgqqttvfvghtgdvmslsl.......apdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaf 234 v+ t ++lw++ tg+ f+gh v + l ++ l+vs d +k wd+ ++ c qt+ gh ++n+i + FUN_000437-T1 598 YVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECVKLkfmmvngKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHV 682 4555566899*****************9866443331111111457789********************************9864 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.0 2.4e-06 0.0015 1 39 [. 419 457 .. 419 466 .. 0.88 2 ! 15.2 0.1 3.5e-05 0.023 10 32 .. 469 491 .. 459 498 .. 0.80 3 ! 17.0 0.2 9.6e-06 0.0062 1 39 [. 500 538 .. 500 556 .. 0.78 4 ! 8.0 0.1 0.0063 4 11 38 .. 552 579 .. 540 602 .. 0.79 5 ? 3.5 0.0 0.16 1e+02 14 31 .. 646 663 .. 624 669 .. 0.88 6 ! 14.8 0.4 4.8e-05 0.03 1 31 [. 673 703 .] 673 703 .] 0.95 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 2.4e-06 Beta-prop_TEP1_C 1 hsdrisalkltddliisAseDrtvKlWdretkkqvGlFv 39 h++++ ++ ++ i + s Drt+K+Wd +t ++ F+ FUN_000437-T1 419 HKNNVLTVCGYKNFIATGSLDRTIKVWDANTGTLIQTFT 457 7777888888899******************99999987 PP == domain 2 score: 15.2 bits; conditional E-value: 3.5e-05 Beta-prop_TEP1_C 10 ltddliisAseDrtvKlWdretk 32 l +++iis s+D+t++lW+ +tk FUN_000437-T1 469 LSKSIIISGSYDKTIRLWSLRTK 491 457899*************9987 PP == domain 3 score: 17.0 bits; conditional E-value: 9.6e-06 Beta-prop_TEP1_C 1 hsdrisalkltddliisAseDrtvKlWdretkkqvGlFv 39 h + + a++ +d++is s+D+t KlW+ ++ k++ v FUN_000437-T1 500 HDGPVWAIERKEDILISGSSDKTAKLWNIRQCKLLFSLV 538 7788999999******************99999875444 PP == domain 4 score: 8.0 bits; conditional E-value: 0.0063 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdretkkqvGlF 38 t + +s s Drtv++Wd ++ + F FUN_000437-T1 552 TCKRAFSGSGDRTVRVWDVSSGICLSSF 579 4466799***********9877666665 PP == domain 5 score: 3.5 bits; conditional E-value: 0.16 Beta-prop_TEP1_C 14 liisAseDrtvKlWdret 31 li+s+ +D +K Wd e+ FUN_000437-T1 646 LIVSSGKDGLIKYWDIEQ 663 79*************875 PP == domain 6 score: 14.8 bits; conditional E-value: 4.8e-05 Beta-prop_TEP1_C 1 hsdrisalkltddliisAseDrtvKlWdret 31 h d+++++++ + iis s D+ v++W+ +t FUN_000437-T1 673 HRDNVNSIHVDSTRIISVSFDHRVRVWNFNT 703 99*************************9775 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.1 1.6e-05 0.01 233 280 .. 413 458 .. 406 472 .. 0.81 2 ! 33.6 0.5 5.3e-11 3.4e-08 169 283 .. 471 584 .. 457 601 .. 0.85 3 ! 21.7 0.4 2.3e-07 0.00015 174 270 .. 600 702 .. 598 703 .] 0.77 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.6e-05 Beta-prop_WDR36-Utp21_2nd 233 vRkfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvflv 280 v + ghkn++ ++ ++ t s+D ti++wd ++g+li +f+ FUN_000437-T1 413 VMDMVGHKNNVLTVCGY--KNFIATGSLDRTIKVWDANTGTLIQTFTG 458 66789999999777655..4689**********************984 PP == domain 2 score: 33.6 bits; conditional E-value: 5.3e-11 Beta-prop_WDR36-Utp21_2nd 169 nqvvitagadkklkfwkfkskklletlkleasisklvlhressllavalddfsilvvDidtrrvvRkfsghknritDltfspda 252 ++++i+++ dk++++w++++k + l + + + ++e l++ + d + ++ i + ++ ++ gh++ + + + + FUN_000437-T1 471 KSIIISGSYDKTIRLWSLRTKACARILMGHDGPVWAIERKEDILISGSSD-KTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTC 553 45789**********************99999999998888888877665.6889***************************** PP Beta-prop_WDR36-Utp21_2nd 253 rWlitasmDstirtwdlpsgkliDvflvesa 283 + + s D t+r+wd++sg + f+v + FUN_000437-T1 554 KRAFSGSGDRTVRVWDVSSGICLSSFNVGQS 584 ***************************9643 PP == domain 3 score: 21.7 bits; conditional E-value: 2.3e-07 Beta-prop_WDR36-Utp21_2nd 174 tagadkklkfwkfkskklletlk........leasisklvlhressllavalddfsilvvDidtrrvvRkfsghknritDltfs 249 ++g+ + + +w++ + + +++++ ++ + ++ ++e++l+ + d i+ Di++ +++ +++gh+ +++ + FUN_000437-T1 600 AVGSGTMVSLWNLTTGDCVHEFSghknrvecVKLKFMMVNGKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSI--H 681 56667777788888877777755322222223344455566899**********************************976..5 PP Beta-prop_WDR36-Utp21_2nd 250 pdarWlitasmDstirtwdlp 270 d+ +i+ s D +r+w+++ FUN_000437-T1 682 VDSTRIISVSFDHRVRVWNFN 702 79999*************975 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 2.2e-08 1.4e-05 67 132 .. 432 496 .. 407 507 .. 0.88 2 ! 44.2 4.6 2.7e-14 1.7e-11 95 293 .. 500 701 .. 494 703 .] 0.81 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 2.2e-08 WDR55 67 klfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWDlRkkkavme 132 + + s D++i+v d++tg+l+++++ h+ i s+ +++ ++++G d t++lW lR+k++ FUN_000437-T1 432 FIATGSLDRTIKVWDANTGTLIQTFT-GHTRGIWSIRFLSKSIIISGSYDKTIRLWSLRTKACARI 496 577999******************98.8********************************998755 PP == domain 2 score: 44.2 bits; conditional E-value: 2.7e-14 WDR55 95 hespiysllvidenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfnirkkklevqseeyeeells.lalvk 189 h+ p+ ++ +e +l++G d t klW +R+ k +++l h+ ++ ++ +d++ k ++ sgd t+ v+++++ + ++s ++ + + +++v FUN_000437-T1 500 HDGPVWAIE-RKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSG-ICLSSFNVGQSTDCtVTTVS 593 677777665.578999********************************************************965.66777777766666244445 PP WDR55 190 eekkvvvGsseGklylfnwgefgahsdrfpghkesidc......lv..pitenivvtgseDGiiRavhllPnrvlgvvGqheelpvekldiskdgk 277 ++ v+ s ++l+n g++ +f+ghk+ ++c +v + + ++v +++DG+i+ + ++ ++ h+ v+++++ d++ FUN_000437-T1 594 YDHGYVAVGSGTMVSLWNLT-TGDCVHEFSGHKNRVECvklkfmMVngKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHR-DNVNSIHV--DST 685 55544444444567888885.6***************94444322311223458999************************9.58999887..667 PP WDR55 278 llassshdqkvkFwni 293 + s+s d++v+ wn FUN_000437-T1 686 RIISVSFDHRVRVWNF 701 799***********96 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 5.9e-07 0.00038 283 341 .] 431 488 .. 424 488 .. 0.79 2 ! 34.9 1.4 1.7e-11 1.1e-08 192 320 .. 513 633 .. 504 642 .. 0.84 3 ! 12.7 0.2 0.0001 0.064 285 340 .. 647 700 .. 636 701 .. 0.86 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 5.9e-07 WD40_MABP1-WDR62_2nd 283 lyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhlisvsgDsCifvWrl 341 ++at + d++++++d ++G ++ t +Gh+ + +++F + +is s D i +W l FUN_000437-T1 431 NFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKS-IIISGSYDKTIRLWSL 488 588888888888888888888888888888888888888754.6788888888888865 PP == domain 2 score: 34.9 bits; conditional E-value: 1.7e-11 WD40_MABP1-WDR62_2nd 192 kliscgaDksilfrkaqktkegvefsrehhvvekttlydmevdaskklvavacqDrnirvynvssgkqkksfkgsqsedgtllkvqlDp 280 lis ++Dk+ + ++++ k + fs v ++ ++ +++d ++k + ++ Dr++rv++vssg sf+ qs d t+ v+ D+ FUN_000437-T1 513 ILISGSSDKTAKLWNIRQCK--LLFSL---VGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQSTDCTVTTVSYDH 596 57888888888877777554..55554...5567789999************************************************8 PP WD40_MABP1-WDR62_2nd 281 sglyvatscsdknlsildfesGecvatvfGhseivtglkF 320 yva+ s +s++++++G+cv Gh + v +k FUN_000437-T1 597 G--YVAVG-SGTMVSLWNLTTGDCVHEFSGHKNRVECVKL 633 6..77764.6779*******************99987654 PP == domain 3 score: 12.7 bits; conditional E-value: 0.0001 WD40_MABP1-WDR62_2nd 285 vatscsdknlsildfesGecvatvfGhseivtglkFtedcrhlisvsgDsCifvWr 340 +++s d ++ +d e+ c+ t+ Gh + v +++ d ++isvs D + vW+ FUN_000437-T1 647 IVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIH--VDSTRIISVSFDHRVRVWN 700 67888899999999999999999999999999987..5889999999999999997 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.1 0.0018 1.1 30 76 .. 415 458 .. 407 472 .. 0.73 2 ! 8.5 0.0 0.0025 1.6 15 67 .. 481 530 .. 467 538 .. 0.81 3 ! 13.9 0.1 5.5e-05 0.035 29 80 .. 535 585 .. 529 596 .. 0.86 4 ! 21.3 0.1 3e-07 0.00019 2 65 .. 592 661 .. 591 665 .. 0.81 5 ! 15.1 0.1 2.4e-05 0.015 11 65 .. 648 701 .. 646 703 .] 0.85 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0018 Beta-prop_WDR75_1st 30 elkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktfvv 76 ++ gh++ v v +n + + sld t+++wd g li+tf+ FUN_000437-T1 415 DMVGHKNNVLTVCG-YKN--FIATGSLDRTIKVWDANTGTLIQTFTG 458 56677776665542.334..356789******************974 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0025 Beta-prop_WDR75_1st 15 dsvkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftd 67 ++++++s +t+ c + l gh v ++ + + s s d t +lw+ + FUN_000437-T1 481 KTIRLWSLRTKACARILMGHDGPVWAIERKED---ILISGSSDKTAKLWNIRQ 530 5799********************99986643...4689**********9765 PP == domain 3 score: 13.9 bits; conditional E-value: 5.5e-05 Beta-prop_WDR75_1st 29 helkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktfvvgyki 80 +l gh+ v v l+ + + + +s s d tvr+wd gi + +f vg++ FUN_000437-T1 535 FSLVGHNGCVFCVDLDDTCK-RAFSGSGDRTVRVWDVSSGICLSSFNVGQST 585 57899999999999998876.79*************************9875 PP == domain 4 score: 21.3 bits; conditional E-value: 3e-07 Beta-prop_WDR75_1st 2 iskdsrfllcasGdsvkvyststeecvhelkghtdlvtGvaln.....psn.hlqvyscsldgtvrlwdf 65 +s d ++ sG +v ++ +t +cvhe+ gh++ v v+l+ + + s+ dg ++ wd FUN_000437-T1 592 VSYDHGYVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECVKLKfmmvnGKKeAGLIVSSGKDGLIKYWDI 661 578999999******************************9986222212331345789999*******97 PP == domain 5 score: 15.1 bits; conditional E-value: 2.4e-05 Beta-prop_WDR75_1st 11 casGd..svkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 +sG+ ++k + + c+++l+gh+d v + ++ + ++ s s d vr+w+f FUN_000437-T1 648 VSSGKdgLIKYWDIEQASCIQTLRGHRDNVNSIHVDST---RIISVSFDHRVRVWNF 701 56664337899999999****************99865...7899***********9 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.4 1.4e-07 8.9e-05 319 395 .. 433 509 .. 411 516 .. 0.89 2 ! 22.3 10.0 1.1e-07 6.9e-05 304 417 .. 499 615 .. 493 622 .. 0.82 3 ! 20.7 4.1 3.3e-07 0.00021 319 413 .. 599 700 .. 589 703 .] 0.82 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.4e-07 Beta-prop_SCAP 319 vvtGsqdhtvrvyrledscclftlqGhsGgitavyidqtmvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvc 395 + tGs d t++v+ + + t+ Gh+ gi ++ ++ sG d +i lw + t + ++gh G v ++ FUN_000437-T1 433 IATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKSIIISGSYDKTIRLWSLRTKACARILMGHDGPVWAIER 509 78********************************999999999***************************9987765 PP == domain 2 score: 22.3 bits; conditional E-value: 1.1e-07 Beta-prop_SCAP 304 ahqkPitvlkaaaGrvvtGsqdhtvrvyrledscclftlqGhsGgitavyidqtmvla.sGGqdGaiclwdvltGsrvshv.yghrGdvtslvct 396 h P+ ++ +++Gs d t +++ + + lf+l Gh G++ +v +d+t a sG d ++ +wdv +G +s g d+t +++ FUN_000437-T1 499 GHDGPVWAIERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAfSGSGDRTVRVWDVSSGICLSSFnVGQSTDCTVTTVS 593 6888888898899999**************************************998868999************88765426777777755443 PP Beta-prop_SCAP 397 .tscvissGlddlisiwdrstg 417 ++ G ++s+w+ +tg FUN_000437-T1 594 yDHGYVAVGSGTMVSLWNLTTG 615 1344677888889999988776 PP == domain 3 score: 20.7 bits; conditional E-value: 3.3e-07 Beta-prop_SCAP 319 vvtGsqdhtvrvyrledscclftlqGhsGgitavyidqtmv........lasGGqdGaiclwdvltGsrvshvyghrGdvtslvcttscvissGl 405 v Gs v ++ l c+ + Gh + +v + mv + s G+dG i wd+ s + + ghr +v s+ + ++ +is + FUN_000437-T1 599 VAVGSG-TMVSLWNLTTGDCVHEFSGHKNRVECVKLKFMMVngkkeaglIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDSTRIISVSF 692 555553.3577788888889999999999999998888887555544446799****************************************** PP Beta-prop_SCAP 406 ddlisiwd 413 d + +w+ FUN_000437-T1 693 DHRVRVWN 700 ******97 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.3 6.7e-07 0.00043 115 207 .. 401 494 .. 372 498 .. 0.82 2 ! 28.7 0.1 1.4e-09 9e-07 123 209 .. 494 578 .. 492 595 .. 0.89 3 ! 10.6 0.5 0.00044 0.28 116 160 .. 660 702 .. 598 703 .] 0.75 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 6.7e-07 Beta-prop_CAF1B_HIR1 115 enketwlv..lkv..lrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrif 199 + k +w+ +kv + Gh+++v ++ ++++ +gs+D t+ +Wd + g+ ++ ++ h + ++ + k +++++ s D+++r++ FUN_000437-T1 401 NLKRNWANgrCKVmdMVGHKNNVLTVCG--YKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSK-SIIISGSYDKTIRLW 486 45555653224552257******99985..5689*********************************999865.688899********* PP Beta-prop_CAF1B_HIR1 200 diktkkvv 207 +++tk ++ FUN_000437-T1 487 SLRTKACA 494 ***99875 PP == domain 2 score: 28.7 bits; conditional E-value: 1.4e-09 Beta-prop_CAF1B_HIR1 123 lkvlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkvvar 209 ++l Gh v+ + +++ lisgs D ta lW+++++k l l h+g v v +d + + + s Dr++r++d+++ +++ FUN_000437-T1 494 ARILMGHDGPVWAI--ERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSS 578 57889999998866..567889*********************************************************99877665 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00044 Beta-prop_CAF1B_HIR1 116 nketwlvlkvlrGhledvyDlswspdskklisgsvDntailWdve 160 + e+ ++++lrGh ++v + ds+++is s D + +W+++ FUN_000437-T1 660 DIEQASCIQTLRGHRDNVNSI--HVDSTRIISVSFDHRVRVWNFN 702 5688889999*******9866..68999**************975 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.1 8.5e-05 0.054 205 264 .. 430 487 .. 412 489 .. 0.88 2 ! 40.5 1.2 4.7e-13 3e-10 53 265 .. 489 701 .. 487 702 .. 0.84 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 8.5e-05 Beta-prop_WDR36-Utp21_1st 205 epvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkewi 264 ++++atgs + +i +wd ++++l+++ + H+ g+ +++fl++ ++++ + D +++ w FUN_000437-T1 430 KNFIATGSLDRTIKVWDANTGTLIQTF-TGHTRGIWSIRFLSK-SIIISGSYDKTIRLWS 487 578999*******************99.57999********76.6899********9995 PP == domain 2 score: 40.5 bits; conditional E-value: 4.7e-13 Beta-prop_WDR36-Utp21_1st 53 rgkevaellkeheekikkllvfgdhlvavdednsllvwkieteelyteiefseeefeitallhpsTYlnKilvgskqGslqlwN 136 r+k +a++l +h++++ + d+l++ ++d++ ++w+i++ +l ++ ++ + ++ ++ + + gs + ++++w+ FUN_000437-T1 489 RTKACARILMGHDGPVWAIERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHN---GCVFCVDLDDTCKRAFSGSGDRTVRVWD 569 7788999999************************************9999886...67778899999***************** PP Beta-prop_WDR36-Utp21_1st 137 irtgkliytfk.sfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvts..isFrtDg....epvlatgss 213 +++g ++ +f+ + ++ t+ + s va+g + + l n+ ++ + +++ ++++v + + F + + +++++ + FUN_000437-T1 570 VSSGICLSSFNvGQSTDCTVTTVSYDHGYVAVGSGT-MVSLWNLTTGDCVHEFSGHKNRVECvkLKFMMVNgkkeAGLIVSSGK 652 **********83334556666666666677777665.799*************988776654116787764455468899999* PP Beta-prop_WDR36-Utp21_1st 214 sGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkewif 265 +G i wd+e+ + +++lr H+ +v+++++ +++ + D +++w f FUN_000437-T1 653 DGLIKYWDIEQASCIQTLR-GHRDNVNSIHVD--STRIISVSFDHRVRVWNF 701 ******************7.5999*****974..455789999999999988 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0023 1.5 9 35 .. 470 496 .. 463 520 .. 0.75 2 ? 3.3 0.0 0.097 62 6 36 .. 507 537 .. 504 552 .. 0.72 3 ! 28.5 2.2 2e-09 1.2e-06 7 154 .. 550 702 .. 544 703 .] 0.80 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0023 Beta-prop_EML_2 9 sepqfvTagdDktvrlWdlekkklvak 35 s+++++++++Dkt+rlW+l++k++ + FUN_000437-T1 470 SKSIIISGSYDKTIRLWSLRTKACARI 496 577899*************99987653 PP == domain 2 score: 3.3 bits; conditional E-value: 0.097 Beta-prop_EML_2 6 thpsepqfvTagdDktvrlWdlekkklvakv 36 ++ +e++ ++++ Dkt lW++++ kl+ ++ FUN_000437-T1 507 IERKEDILISGSSDKTAKLWNIRQCKLLFSL 537 5667788889999999999999888877665 PP == domain 3 score: 28.5 bits; conditional E-value: 2e-09 Beta-prop_EML_2 7 hpsepqfvTagdDktvrlWdlekkklvakvkleke..arsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfsp......d 92 + + +++++ D+tvr+Wd+++ ++ + +++++ ++ ++s d+ ++avG+ v +++ +t++ v+e++ +k++++++k + + FUN_000437-T1 550 DDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQStdCTVTTVSYDHGYVAVGSG-TMVSLWNLTTGDCVHEFSGHKNRVECVKLKFmmvngkK 642 556677899*********************9987612666789999999999964.46778899999******999999999886532232224 PP Beta-prop_EML_2 93 gklLavgs.hdnkiylYdvskkykkvgklkghssfithlDwsedskylqsnsgdyellfwdak 154 ++ L v+s +d+ i+ +d+ ++ + +++l+gh + + ++ + ds+ + s s d ++ +w+ + FUN_000437-T1 643 EAGLIVSSgKDGLIKYWDI-EQASCIQTLRGHRDNVNSI--HVDSTRIISVSFDHRVRVWNFN 702 5567776438********8.56889************98..5799999999999999999865 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.3 0.00041 0.26 57 119 .. 434 488 .. 411 495 .. 0.64 2 ! 14.3 0.2 2.8e-05 0.018 39 139 .. 498 590 .. 492 595 .. 0.74 3 ! 27.4 0.9 3e-09 1.9e-06 54 159 .. 596 701 .. 589 703 .] 0.91 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00041 Beta-prop_WDR41 57 asagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdi 119 a+ + d ++ +wd +tg + + ght+ i +i ++ ++i++ s dkt+ +w + FUN_000437-T1 434 ATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLS--------KSIIISGSYDKTIRLWSL 488 3344566777777777777777777777777665443........246666666666666655 PP == domain 2 score: 14.3 bits; conditional E-value: 2.8e-05 Beta-prop_WDR41 39 kehkdivrflvqiddfrfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdiesgrqlkkisdfq 132 +h + v + + +d+ ++s + d + lw+++ + l+ l gh + + + +++++ ++ s d+tv vwd+ sg l + q FUN_000437-T1 498 MGHDGPVWAIERKEDI-LISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCV---DL----DDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQ 583 5666666666565665.56778888999****************8754333...33....3445556889**************9999988888 PP Beta-prop_WDR41 133 stvkslt 139 st ++t FUN_000437-T1 584 STDCTVT 590 8766665 PP == domain 3 score: 27.4 bits; conditional E-value: 3e-09 Beta-prop_WDR41 54 frfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdiesgrqlkkisdfqstvksltvlerldlw 147 + +++ g +v lw++ tg+ + e+ gh +++ + + + ++++ li+++ d + wdie ++ + + v s+ v + + FUN_000437-T1 596 HGYVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECVKLKFMMVNGKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDSTRIIS 689 5678889999************************99887777777888999999999999***************************9999999 PP Beta-prop_WDR41 148 lsggsdlrvwnr 159 +s +rvwn FUN_000437-T1 690 VSFDHRVRVWNF 701 **********95 PP >> F-box-like F-box-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.8 2.0 8.6e-15 5.5e-12 2 46 .. 334 378 .. 333 379 .. 0.95 Alignments for each domain: == domain 1 score: 45.8 bits; conditional E-value: 8.6e-15 F-box-like 2 sdLPdEiLlqIFsyLdpkdLlrlalVCrrWrelasddsLWrrlcl 46 + LP+ + l+I+s+L pk+Ll +++V++ Wr+las+d+LW++ c FUN_000437-T1 334 ALLPEPLALHILSFLVPKELLFVCQVSKTWRRLASRDELWQSKCK 378 68***************************************9885 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.19 1.2e+02 239 271 .. 428 460 .. 393 463 .. 0.71 2 ! 14.2 0.1 3.2e-05 0.02 231 309 .. 462 535 .. 458 558 .. 0.85 3 ! 24.1 0.1 3.2e-08 2e-05 239 310 .. 593 669 .. 539 670 .. 0.78 4 ! 14.7 0.1 2.4e-05 0.015 240 302 .. 643 701 .. 635 703 .] 0.80 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.19 Beta-prop_DCAF4 239 qeeqlllaadmaGkiklwdlratkcvkqyeGhv 271 ++++ + + +ik+wd + ++ + Gh+ FUN_000437-T1 428 GYKNFIATGSLDRTIKVWDANTGTLIQTFTGHT 460 44567777788889*****************97 PP == domain 2 score: 14.2 bits; conditional E-value: 3.2e-05 Beta-prop_DCAF4 231 avtsvqllqeeqlllaadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllr 309 + s++ l + ++++ +i+lw lr++ c + Gh ++ +e +l++ d +++w +++++ll FUN_000437-T1 462 GIWSIRFLSK-SIIISGSYDKTIRLWSLRTKACARILMGHDGPV----WAIERKEDILISGSSDKTAKLWNIRQCKLLF 535 5667887765.56777788899******************9754....347889**********************996 PP == domain 3 score: 24.1 bits; conditional E-value: 3.2e-08 Beta-prop_DCAF4 239 qeeqlllaadmaGkiklwdlratkcvkqyeGhvneyaylplhv.....neeeGllvavGqdcytriwslkdahllrt 310 ++ +a + lw+l + cv++++Gh+n ++ l+ ++e Gl+v+ G+d + w +++a ++t FUN_000437-T1 593 SYDHGYVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECVKLKFmmvngKKEAGLIVSSGKDGLIKYWDIEQASCIQT 669 4445555555566799******************998877653222225789********************99988 PP == domain 4 score: 14.7 bits; conditional E-value: 2.4e-05 Beta-prop_DCAF4 240 eeqlllaadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwsl 302 e l++++ G ik wd+ + c++ +Gh+++ +hv+ +++v d r+w + FUN_000437-T1 643 EAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVN--SIHVDST--RIISVSFDHRVRVWNF 701 44456778889*********************9876..4677654..5778899999999975 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.1 0.0 0.00019 0.12 226 274 .. 422 469 .. 408 477 .. 0.73 2 ! 14.9 0.0 2.5e-05 0.016 6 75 .. 430 498 .. 425 507 .. 0.82 3 ! 8.3 0.0 0.0026 1.7 12 95 .. 477 558 .. 469 561 .. 0.81 4 ! 11.0 0.0 0.0004 0.25 3 67 .. 508 572 .. 506 576 .. 0.90 5 ! 20.8 1.0 4e-07 0.00026 9 139 .. 556 694 .. 548 696 .. 0.80 6 ? 3.9 0.1 0.059 38 3 25 .. 681 703 .] 679 703 .] 0.84 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00019 Beta-prop_WDR90_POC16_2nd 226 sslavsedarylltag.dkvikvwdysmkldinfqvfiGhsekvqqvaft 274 l+v+ ++++t++ d++ikvwd ++ + +q f Gh+ + + f FUN_000437-T1 422 NVLTVCGYKNFIATGSlDRTIKVWDANTG--TLIQTFTGHTRGIWSIRFL 469 56777888888888655888888887765..4568888888888888875 PP == domain 2 score: 14.9 bits; conditional E-value: 2.5e-05 Beta-prop_WDR90_POC16_2nd 6 rrqlatvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehk 75 ++ +at s D+ti++Wd +t + + f+ ++ ++ f sk+++++G+ + ++r +s+++ + FUN_000437-T1 430 KNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFL-SKSIIISGSYDKTIRLWSLRTKACARILM 498 66799***************999999*9999999999997.56788999999999999998876555444 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0026 Beta-prop_WDR90_POC16_2nd 12 vseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgeylys 95 s D+tir+W l t ++ ++ P+ a +++++++G+s+ + + +++++ +ll h+g v + + + + +s FUN_000437-T1 477 GSYDKTIRLWSLRTKACARILM-GHDGPVW-AIERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFS 558 5899********9988776666.5677764.56789999****************************99998877777666666 PP == domain 4 score: 11.0 bits; conditional E-value: 0.0004 Beta-prop_WDR90_POC16_2nd 3 dksrrqlatvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsvea 67 ++++ l s+D+t ++W++ + l+ ++ ++ + +v + + ++G+ + +vrv++v++ FUN_000437-T1 508 ERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSS 572 55666677889**************************************************9986 PP == domain 5 score: 20.8 bits; conditional E-value: 4e-07 Beta-prop_WDR90_POC16_2nd 9 latvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtgl..vf.... 86 s D+t+r+Wd+++ l f+ + + c+v+ ++ +++ s +v +++++ + + e++ h+ +v + f FUN_000437-T1 556 AFSGSGDRTVRVWDVSSGICLSSFNVGQSTDCTVTTVSYDHGYVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECVklKFmmvn 639 556699****************************998888877666677799*****************999866411442222 PP Beta-prop_WDR90_POC16_2nd 87 .spdgeylysacslGslalydaseeey.evlrvlgnvvardeelgpealavseds 139 +++ ++ s+++ G + +d+++ ++ + lr + v + ++++++vs d FUN_000437-T1 640 gKKEAGLIVSSGKDGLIKYWDIEQASCiQTLRGHRDNVNSIHVDSTRIISVSFDH 694 234556899*************998764789999999988888888899988775 PP == domain 6 score: 3.9 bits; conditional E-value: 0.059 Beta-prop_WDR90_POC16_2nd 3 dksrrqlatvseDetiriWdldt 25 + + ++ vs D+ +r+W+ +t FUN_000437-T1 681 HVDSTRIISVSFDHRVRVWNFNT 703 56678999***********9886 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.1 0.069 44 196 230 .. 418 450 .. 404 459 .. 0.59 2 ! 16.5 0.1 9.8e-06 0.0063 157 227 .. 461 528 .. 451 544 .. 0.84 3 ! 21.2 4.0 3.7e-07 0.00024 62 225 .. 540 699 .. 523 703 .] 0.60 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.069 Beta-prop_EML 196 ahegsvfsllvlkdgtllsgggkdgkivawdanle 230 h+++v++++ k+ ++ +g d++i+ wdan FUN_000437-T1 418 GHKNNVLTVCGYKN--FIATGSLDRTIKVWDANTG 450 36666666666654..4555666777777776654 PP == domain 2 score: 16.5 bits; conditional E-value: 9.8e-06 Beta-prop_EML 157 kyvlclafsengdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivawda 227 + ++++ f ++ +i+G + +i +Ws t+ + + + h+g+v+++ +d +l+sg +d++++ w+ FUN_000437-T1 461 RGIWSIRFLSKSIIISGSYDKTIRLWSLRTKACARILM-GHDGPVWAIERKED-ILISG-SSDKTAKLWNI 528 56899**********************99999888777.9********99877.66665.78888888874 PP == domain 3 score: 21.2 bits; conditional E-value: 3.7e-07 Beta-prop_EML 62 fergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkk.hiaFWtle.gkklekkkgifekse. 154 ++ v c++ + a s ++++ vWd+++g l++ ++ + + + v+ +d+ v +G ++ W+l+ g+ +++ +g ++ e FUN_000437-T1 540 HNGCVFCVDLDD----TCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQSTDCTVTTVSYDHGY-VAVGSGtMVSLWNLTtGDCVHEFSGHKNRVEc 630 445555555543....23345556667777888888888888887777777777777766554.45555414667887623444555555554432 PP Beta-prop_EML 155 .kpkyvlclafsengdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivaw 225 k k+++ +e g +++ ++G i W+ ++ ++ ++++ h+ +v s++v + ++ ++ d+++ w FUN_000437-T1 631 vKLKFMMVNGKKEAGLIVSSGKDGLIKYWDIEQASCIQTLR-GHRDNVNSIHVDSTRIISVS--FDHRVRVW 699 26777777777777778888888888888877777777766.78888888887766555444..34444444 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.0 4.8e-05 0.031 141 191 .. 419 467 .. 404 473 .. 0.85 2 ? 4.5 0.0 0.029 19 156 191 .. 473 508 .. 469 511 .. 0.88 3 ! 10.1 0.0 0.00058 0.37 99 185 .. 503 584 .. 500 601 .. 0.79 4 ? -0.0 0.0 0.68 4.3e+02 165 194 .. 606 635 .. 583 654 .. 0.85 5 ? 3.1 0.1 0.076 48 132 173 .. 665 703 .] 634 703 .] 0.62 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 4.8e-05 Beta-prop_SPT8 141 hsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgatselsale 191 h+ n+l + + ++ + +gs d+ i wd ntg+ i+ + g+t + ++ FUN_000437-T1 419 HK--NNVLTVCGYKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIR 467 44..48899999999999**************************9887765 PP == domain 2 score: 4.5 bits; conditional E-value: 0.029 Beta-prop_SPT8 156 kflsgswdkkilewdlntgkvineykgatselsale 191 ++sgs+dk i w l+t+ + g+++ + a+e FUN_000437-T1 473 IIISGSYDKTIRLWSLRTKACARILMGHDGPVWAIE 508 589*******************99999999888887 PP == domain 3 score: 10.1 bits; conditional E-value: 0.00058 Beta-prop_SPT8 99 pvyslevnkealfllsGldnGgitlqgvrydeGriahylkakhsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgats 185 pv+++e +++ l+sG + + +l +r +++ l +h+ v + l++t ++ +sgs d+ + wd+ g +++ +s FUN_000437-T1 503 PVWAIERKEDI--LISGSSDKTAKLWNIRQ--CKLLFSLV-GHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQS 584 77777777765..57888888888888885..45666666.599******************************9999999986555 PP == domain 4 score: -0.0 bits; conditional E-value: 0.68 Beta-prop_SPT8 165 kilewdlntgkvineykgatselsalelrp 194 + w+l tg+ ++e+ g++ ++ +++l+ FUN_000437-T1 606 MVSLWNLTTGDCVHEFSGHKNRVECVKLKF 635 5677****************9999888775 PP == domain 5 score: 3.1 bits; conditional E-value: 0.076 Beta-prop_SPT8 132 riahylkakhsnvvnilrlnstedkflsgswdkkilewdlnt 173 + ++l+ +h + vn ++++s ++++s s+d+++ w++nt FUN_000437-T1 665 SCIQTLR-GHRDNVNSIHVDS--TRIISVSFDHRVRVWNFNT 703 3345566.4888777766654..6789999999998888875 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.1 0.00028 0.18 28 83 .. 433 490 .. 419 507 .. 0.82 2 ! 16.1 0.6 8.8e-06 0.0056 36 87 .. 525 575 .. 508 631 .. 0.71 3 ? 2.2 0.1 0.15 98 26 97 .. 599 666 .. 583 667 .. 0.70 4 ! 7.3 0.0 0.0041 2.6 26 80 .. 646 700 .. 637 702 .. 0.82 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00028 Beta-prop_IFT122_1st 28 laags...rllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtskl 83 +a+gs + v+d++ gtl+q + gh ++ + + + sgs dk++ +w+ + FUN_000437-T1 433 IATGSldrTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKS-IIISGSYDKTIRLWSLRT 490 566653324679***********************98764.688***********8665 PP == domain 2 score: 16.1 bits; conditional E-value: 8.8e-06 Beta-prop_IFT122_1st 36 vydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegil 87 +++ + ll l gh+ v+cv kr sgs d++v +w gi FUN_000437-T1 525 LWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSS-GIC 575 566778899***********************************7543.333 PP == domain 3 score: 2.2 bits; conditional E-value: 0.15 Beta-prop_IFT122_1st 26 lilaagsrllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegilkythndaiqc 97 + + +g+ + +++ + g ++ + ghk+ v cv + +g + +i +s +g++ky + c FUN_000437-T1 599 VAVGSGTMVSLWNLTTGDCVHEFSGHKNRVECVKLK---FMMVNGKKEA-GLIVSSGKDGLIKYWDIEQASC 666 455567777789999999**************9653...3344444444.4555666688888876665555 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0041 Beta-prop_IFT122_1st 26 lilaagsrllv..ydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwt 80 li+++g l+ +d + + +q l+gh+d v + d r+ s s d+ v +w FUN_000437-T1 646 LIVSSGKDGLIkyWDIEQASCIQTLRGHRDNVNSIH--VDSTRIISVSFDHRVRVWN 700 677777654432269999**************9875..699*************996 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.0 0.0019 1.2 218 280 .] 431 486 .. 418 486 .. 0.86 2 ! 12.4 0.1 0.00017 0.11 218 280 .] 472 526 .. 469 526 .. 0.90 3 ! 16.1 0.8 1.3e-05 0.0081 150 280 .] 575 699 .. 548 699 .. 0.69 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0019 Beta-prop_EIPR1 218 nklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 n ++t d +++++D t + ++++ +h+ +++++f + + +i+s+s d+t++Lw FUN_000437-T1 431 NFIATGSLDRTIKVWDAN-----TGTLIQTFTGHTRGIWSIRFLS--KSIIISGSYDKTIRLW 486 445666679999999998.....6677899*************76..68************** PP == domain 2 score: 12.4 bits; conditional E-value: 0.00017 Beta-prop_EIPR1 218 nklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 ++++ d ++ ++ +R t++ + l +h+ v++++ ++++++s+ssd+t kLw FUN_000437-T1 472 SIIISGSYDKTIRLWSLR-----TKACARILMGHDGPVWAIE---RKEDILISGSSDKTAKLW 526 5778888999********.....8899999*********996...6899************** PP == domain 3 score: 16.1 bits; conditional E-value: 1.3e-05 Beta-prop_EIPR1 150 evskyslggeelrvaAldphdsslvlvacesglqliDlRakkkksvanvetlhgfgkvravd..fd....pakknklltagddgvvlihDiRyd 237 + s++++g+++ + +d v+v + + ++l+ l + + ++ e++ + + v++v f +++++ ++++g+dg ++++Di FUN_000437-T1 575 CLSSFNVGQSTDCTVTTVSYDHGYVAVGSGTMVSLWNLTTGDCVH----EFSGHKNRVECVKlkFMmvngKKEAGLIVSSGKDGLIKYWDIE-- 662 555666666333333444566677777777777777777766554....3333333333333112211114567889**************9.. PP Beta-prop_EIPR1 238 gsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 ++ +++l++h v+++++ + + i+s s d+ ++ w FUN_000437-T1 663 ---QASCIQTLRGHRDNVNSIHVDSTR---IISVSFDHRVRVW 699 ...6667899************99987...99******99999 PP >> F-box F-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.8 0.8 1.9e-10 1.2e-07 3 42 .. 335 374 .. 333 375 .. 0.95 Alignments for each domain: == domain 1 score: 31.8 bits; conditional E-value: 1.9e-10 F-box 3 dLPdellleIlsrLdpkdllrlslVSkrwrslvkslklwk 42 LP+ l l+Ils+L pk+ll ++VSk+wr+l+++++lw+ FUN_000437-T1 335 LLPEPLALHILSFLVPKELLFVCQVSKTWRRLASRDELWQ 374 69************************************96 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.9 0.6 1.9e-05 0.012 92 154 .. 428 489 .. 402 496 .. 0.83 2 ! 8.6 0.0 0.0016 1 181 233 .. 493 543 .. 487 546 .. 0.84 3 ! 9.5 0.4 0.00087 0.56 94 155 .. 512 572 .. 506 594 .. 0.88 4 ? 0.5 0.1 0.48 3e+02 108 154 .. 609 662 .. 577 665 .. 0.66 5 ! 8.9 0.5 0.0013 0.83 84 153 .. 634 701 .. 624 703 .] 0.78 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 1.9e-05 NBCH_WD40 92 senfliscGnwensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevl 154 + +i+ G+ + + +v + G l+q+ h + ++ s s++++Gsyd t+ +w++ FUN_000437-T1 428 GYKNFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLS-KSIIISGSYDKTIRLWSLR 489 44556888999*********************99999999876.68999***********875 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0016 NBCH_WD40 181 plhilcGhddiitclfvsveldivisGskdgtcifhtlreGryvrslrhpsga 233 +il Ghd + ++ + di+isGs d t + +r+ + + sl +g+ FUN_000437-T1 493 CARILMGHDGPVWAI--ERKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGC 543 5789*****988765..66779******************9999998776666 PP == domain 3 score: 9.5 bits; conditional E-value: 0.00087 NBCH_WD40 94 nfliscGnwensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlr 155 + li G+ + + ++ +++ +l+ s+ h+ v cv + + +Gs d tv vw+v+ FUN_000437-T1 512 DILI-SGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSS 572 4444.58889999999************************99999**************986 PP == domain 4 score: 0.5 bits; conditional E-value: 0.48 NBCH_WD40 108 vislsdGrlvqsirqhkdvvscvavt.......sdgsvlatGsydttvmvwevl 154 + l+ G+ v + + hk+ v cv + + ++++ +d + w++ FUN_000437-T1 609 LWNLTTGDCVHEFSGHKNRVECVKLKfmmvngkKEAGLIVSSGKDGLIKYWDIE 662 456788999999999999999987531111111233456666666666666665 PP == domain 5 score: 8.9 bits; conditional E-value: 0.0013 NBCH_WD40 84 cfatlqtksenfliscGnwensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwev 153 f ++ k e li + + +++ +q++r h+d v ++ v s + +++ s+d v vw+ FUN_000437-T1 634 KFMMVNGKKEAGLIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIHVDS--TRIISVSFDHRVRVWNF 701 55566666666677666677778888899999**************99866..5577889********85 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 2.5e-05 0.016 174 262 .. 417 506 .. 394 507 .. 0.82 2 ? 2.7 0.0 0.15 95 225 249 .. 509 533 .. 507 547 .. 0.78 3 ? 0.4 0.0 0.78 5e+02 5 23 .. 553 572 .. 550 593 .. 0.74 4 ? 3.7 0.0 0.074 47 210 251 .. 621 668 .. 605 679 .. 0.72 5 ? 2.9 0.0 0.14 88 225 245 .. 682 702 .. 669 703 .] 0.81 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 2.5e-05 Beta-prop_RIG_2nd 174 splesnklAvvandkvivilefkeeernletlkkitasa...ekasitsvkwsnansnlllsfsidgkvkvWdleepekeeltitykcpmlc 262 ++n+l v++ +++i ++++ + ++ + ++ + i s+++ ++ +++s s+d ++++W+l++++ +++++ ++ p+++ FUN_000437-T1 417 VGHKNNVLTVCGYKNFIATGSLDRTIKVWDANTGTLIQTftgHTRGIWSIRFL--SKSIIISGSYDKTIRLWSLRTKACARILMGHDGPVWA 506 5567899************9999999999986655444423388888888885..5789*******************************95 PP == domain 2 score: 2.7 bits; conditional E-value: 0.15 Beta-prop_RIG_2nd 225 ansnlllsfsidgkvkvWdleepek 249 +++++l+s s d ++k+W++++ + FUN_000437-T1 509 RKEDILISGSSDKTAKLWNIRQCKL 533 67899***************98776 PP == domain 3 score: 0.4 bits; conditional E-value: 0.78 Beta-prop_RIG_2nd 5 nkiAl.gvsDrrvalldlsk 23 k A+ g +Dr v+++d+s+ FUN_000437-T1 553 CKRAFsGSGDRTVRVWDVSS 572 55555256799999999885 PP == domain 4 score: 3.7 bits; conditional E-value: 0.074 Beta-prop_RIG_2nd 210 asaekasitsvkw......snansnlllsfsidgkvkvWdleepekee 251 s +k+++++vk ++++ l++s++ dg +k Wd+e+ + + FUN_000437-T1 621 FSGHKNRVECVKLkfmmvnGKKEAGLIVSSGKDGLIKYWDIEQASCIQ 668 4566677777664222221255678999**************988655 PP == domain 5 score: 2.9 bits; conditional E-value: 0.14 Beta-prop_RIG_2nd 225 ansnlllsfsidgkvkvWdle 245 +s ++s+s+d +v+vW+ + FUN_000437-T1 682 VDSTRIISVSFDHRVRVWNFN 702 567889*************86 PP >> DUF4508 Domain of unknown function (DUF4508) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.2 6.4e-05 0.041 1 43 [. 22 63 .. 22 76 .. 0.87 2 ! 14.4 0.3 7.7e-05 0.049 4 33 .. 285 315 .. 283 333 .. 0.82 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 6.4e-05 DUF4508 1 eaelryvveWfeewselqredFlevlveklvpkakvnglldal 43 e++l y+ +W+e+w++ r d +e l+ ++ pk +++ l + + FUN_000437-T1 22 EQQLDYICQWMEKWNDQVRRDLIELLLPRCNPK-QITFLWTVV 63 589***************************999.777766655 PP == domain 2 score: 14.4 bits; conditional E-value: 7.7e-05 DUF4508 4 lryvveWfe.ewselqredFlevlveklvpk 33 +++v+Wfe +ws q+++Fl+++++ l p+ FUN_000437-T1 285 AQCLVQWFElHWSGWQKNEFLQIFLRVLEPS 315 68******868************99988776 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.32 2.1e+02 107 144 .. 415 451 .. 411 457 .. 0.80 2 ! 15.7 0.1 1.2e-05 0.0076 109 143 .. 457 491 .. 452 502 .. 0.89 3 ? 4.4 0.0 0.031 20 111 152 .. 500 540 .. 495 547 .. 0.75 4 ? 4.4 0.1 0.033 21 110 159 .. 539 589 .. 533 605 .. 0.77 5 ? 3.0 0.2 0.086 55 104 141 .. 666 702 .. 648 703 .] 0.89 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.32 Beta-prop_DCAF12 107 drkghkdwifaiawlsdtvavsGsrdgtlalwrvdpdk 144 d ghk+ + ++ ++ + +Gs d t+ +w ++ + FUN_000437-T1 415 DMVGHKNNVLTVCGYKNFI-ATGSLDRTIKVWDANTGT 451 6779999999999887665.58**********988755 PP == domain 2 score: 15.7 bits; conditional E-value: 1.2e-05 Beta-prop_DCAF12 109 kghkdwifaiawlsdtvavsGsrdgtlalwrvdpd 143 gh+ i +i +ls ++++sGs d t+ lw + + FUN_000437-T1 457 TGHTRGIWSIRFLSKSIIISGSYDKTIRLWSLRTK 491 59****************************98765 PP == domain 3 score: 4.4 bits; conditional E-value: 0.031 Beta-prop_DCAF12 111 hkdwifaiawlsdtvavsGsrdgtlalwrvdpdklnasialk 152 h + ai ++ + +sGs d t lw++ + kl s++ + FUN_000437-T1 500 HDGPVWAIER-KEDILISGSSDKTAKLWNIRQCKLLFSLVGH 540 5555666654.46789*************9987776666655 PP == domain 4 score: 4.4 bits; conditional E-value: 0.033 Beta-prop_DCAF12 110 ghkdwifaiawlsdtv..avsGsrdgtlalwrvdpdklnasialkneaelpv 159 gh+ +f+++ l dt a sGs d t+ +w v + +s+ + ++ v FUN_000437-T1 539 GHNGCVFCVD-LDDTCkrAFSGSGDRTVRVWDVSSGICLSSFNVGQSTDCTV 589 6777777776.556543389**************999988887777666555 PP == domain 5 score: 3.0 bits; conditional E-value: 0.086 Beta-prop_DCAF12 104 clGdrkghkdwifaiawlsdtvavsGsrdgtlalwrvd 141 c+ +gh+d + +i + t ++s s d + +w+ + FUN_000437-T1 666 CIQTLRGHRDNVNSIH-VDSTRIISVSFDHRVRVWNFN 702 777889********96.888999************976 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.026 17 51 88 .. 431 468 .. 395 471 .. 0.86 2 ? 4.0 0.1 0.13 83 54 87 .. 557 593 .. 510 597 .. 0.76 3 ? 4.8 0.0 0.073 47 56 87 .. 600 632 .. 595 638 .. 0.82 4 ? 5.7 0.0 0.04 25 52 87 .. 646 681 .. 637 685 .. 0.88 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.026 ANAPC4_WD40 51 klLavaysdgevrlldvesgklvhslsaksdkitcleW 88 +++a + d ++++ d+++g+l+++++ ++ i ++ + FUN_000437-T1 431 NFIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRF 468 7999**********************999888877766 PP == domain 2 score: 4.0 bits; conditional E-value: 0.13 ANAPC4_WD40 54 avaysdgevrlldvesgklvhslsaksdk...itcle 87 + d +vr+ dv+sg +++s+++++++ +t+++ FUN_000437-T1 557 FSGSGDRTVRVWDVSSGICLSSFNVGQSTdctVTTVS 593 56778899999**********9999998666666655 PP == domain 3 score: 4.8 bits; conditional E-value: 0.073 ANAPC4_WD40 56 aysdg.evrlldvesgklvhslsaksdkitcle 87 a+ +g v+l + +g++vh++s +++++ c++ FUN_000437-T1 600 AVGSGtMVSLWNLTTGDCVHEFSGHKNRVECVK 632 444442799******************999986 PP == domain 4 score: 5.7 bits; conditional E-value: 0.04 ANAPC4_WD40 52 lLavaysdgevrlldvesgklvhslsaksdkitcle 87 l++ + +dg ++ d+e++ ++++l+ ++d++++++ FUN_000437-T1 646 LIVSSGKDGLIKYWDIEQASCIQTLRGHRDNVNSIH 681 6788899***********************999887 PP >> Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.1 0.00083 0.53 184 211 .. 428 455 .. 391 457 .. 0.79 2 ? 3.1 0.1 0.065 42 186 209 .. 471 494 .. 464 498 .. 0.83 3 ! 7.7 0.5 0.0027 1.7 189 215 .. 556 582 .. 543 665 .. 0.86 4 ! 8.1 0.5 0.002 1.3 179 205 .. 679 703 .] 661 703 .] 0.85 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00083 Beta-prop_Nup120_160 184 eddtllftvclDhkLRvWslktgkcvat 211 + ++++ t +lD++++vW+ +tg+++ t FUN_000437-T1 428 GYKNFIATGSLDRTIKVWDANTGTLIQT 455 6899********************9976 PP == domain 2 score: 3.1 bits; conditional E-value: 0.065 Beta-prop_Nup120_160 186 dtllftvclDhkLRvWslktgkcv 209 ++++++ + D+++R+Wsl+t+ c+ FUN_000437-T1 471 KSIIISGSYDKTIRLWSLRTKACA 494 667777789************997 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0027 Beta-prop_Nup120_160 189 lftvclDhkLRvWslktgkcvatidll 215 +f+ + D+++RvW++++g c+++ ++ FUN_000437-T1 556 AFSGSGDRTVRVWDVSSGICLSSFNVG 582 677789***************998887 PP == domain 4 score: 8.1 bits; conditional E-value: 0.002 Beta-prop_Nup120_160 179 avveseddtllftvclDhkLRvWslkt 205 +++ d+t +++v+ Dh++RvW+ +t FUN_000437-T1 679 SIHV--DSTRIISVSFDHRVRVWNFNT 703 4443..8999**************986 PP >> Beta-prop_WDR11_2nd WDR11 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.1 0.0049 3.1 33 82 .. 432 481 .. 418 485 .. 0.88 2 ! 11.2 0.6 0.00022 0.14 238 323 .. 575 664 .. 561 672 .. 0.77 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0049 Beta-prop_WDR11_2nd 33 lvalgtqsGtidvvdvsanavaasfsvhssvvrGlrwlGnsrlvsfsysq 82 ++a g+ + ti+v d+++ ++ ++f+ h+ + +r+l s ++s sy + FUN_000437-T1 432 FIATGSLDRTIKVWDANTGTLIQTFTGHTRGIWSIRFLSKSIIISGSYDK 481 57888889999999999999999999999999999999999999999976 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00022 Beta-prop_WDR11_2nd 238 psssfv...ssdglvtamayrlphvvlGdrlGnirwwdvttGls.ssfnthreGirrikfsp.vvagdksrGriavlfydntfsvfdlds 322 ssf s+d vt+++y +v +G + w++ttG f+ h++ + +k+ +v g k G i+ +d + +d+++ FUN_000437-T1 575 CLSSFNvgqSTDCTVTTVSYDHGYVAVGSG-TMVSLWNLTTGDCvHEFSGHKNRVECVKLKFmMVNGKKEAGLIVSSGKDGLIKYWDIEQ 663 55666433389*****************75.47899******87258********98887651456888889998888888888888876 PP Beta-prop_WDR11_2nd 323 q 323 FUN_000437-T1 664 A 664 5 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.3 0.00062 0.4 12 99 .. 408 495 .. 406 532 .. 0.68 2 ? 2.2 0.3 0.19 1.2e+02 73 134 .. 509 570 .. 504 594 .. 0.74 3 ? 0.2 0.1 0.79 5e+02 289 326 .. 563 600 .. 543 611 .. 0.69 4 ? 0.7 0.0 0.55 3.5e+02 271 310 .. 637 675 .. 611 700 .. 0.57 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00062 WD40_RFWD3 12 eggcRvlaynellalLvvsqpssnallfkGyGvkkissldlkssqyikl...HskaiRdlaFnseqdslllsaslDktlkltsllsntvvq 99 +g+c+v+++ + + ++ +n + +G + i++ d ++ i+ H++ i ++ F s+ s+++s s Dkt++l sl +++ + FUN_000437-T1 408 NGRCKVMDMVGHKNNVLTVCGYKNF-IATGSLDRTIKVWDANTGTLIQTftgHTRGIWSIRFLSK--SIIISGSYDKTIRLWSLRTKACAR 495 6788888887777666555555555.568887788888888887777663336666666667665..899999999999999998877655 PP == domain 2 score: 2.2 bits; conditional E-value: 0.19 WD40_RFWD3 73 eqdslllsaslDktlkltsllsntvvqtYetdspvWsCcWseddsnylyaGlqnGsvlvfDi 134 +++ +l+s s Dkt+kl ++ + +++ + ++ C+ d ++ ++G + +v v+D+ FUN_000437-T1 509 RKEDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRAFSGSGDRTVRVWDV 570 56789999999999999999887777776666666666666666666677766666666665 PP == domain 3 score: 0.2 bits; conditional E-value: 0.79 WD40_RFWD3 289 ksvllWdassgkqlqklsvsspv.ldvcsfevnnksfLa 326 +v +Wd+ssg +l++++v+++ v++++ ++ ++a FUN_000437-T1 563 RTVRVWDVSSGICLSSFNVGQSTdCTVTTVS-YDHGYVA 600 57899****9999999998654313444443.3444555 PP == domain 4 score: 0.7 bits; conditional E-value: 0.55 WD40_RFWD3 271 kspekddk.llvaagdeasksvllWdassgkqlqklsvssp 310 k+++ l+v +g++ ++ Wd+++++++q+l+ ++ FUN_000437-T1 637 MVNGKKEAgLIVSSGKD--GLIKYWDIEQASCIQTLRGHRD 675 33333333044444443..4688899999999999985443 PP >> CNH CNH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.14 89 219 249 .. 430 461 .. 410 467 .. 0.81 2 ? 4.0 0.0 0.08 51 4 67 .. 495 558 .. 492 589 .. 0.82 3 ? 3.5 0.0 0.12 74 213 253 .. 590 630 .. 586 632 .. 0.92 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.14 CNH 219 epyl.lafsenfieirdvetgelvqvlagrkl 249 ++++ ++ ++ i ++d++tg l+q+++g+++ FUN_000437-T1 430 KNFIaTGSLDRTIKVWDANTGTLIQTFTGHTR 461 555556677899***************99875 PP == domain 2 score: 4.0 bits; conditional E-value: 0.08 CNH 4 klllGteeGlyvlnlsqkreivkiidkkkvtqlevleelnlllllsGkdkkLyvyplsaLeek..s 67 ++l+G + ++ ++++ +i ++ k +l+ + + +ll +l G + +++ ++l++ ++ s FUN_000437-T1 495 RILMGHDGPVWAIERK--EDILISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLDDTCKRafS 558 7888888889999999..777777889*******************************99998652 PP == domain 3 score: 3.5 bits; conditional E-value: 0.12 CNH 213 eavaylepyllafsenfieirdvetgelvqvlagrklrfln 253 ++v y ++y+ + s +++ +++ tg v++++g+k r+ + FUN_000437-T1 590 TTVSYDHGYVAVGSGTMVSLWNLTTGDCVHEFSGHKNRVEC 630 7899********************************99876 PP >> Beta-prop_NOL10_N Nucleolar protein 10-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.27 1.7e+02 131 212 .. 418 497 .. 410 525 .. 0.77 2 ? 10.0 0.4 0.00071 0.45 66 212 .. 515 670 .. 504 681 .. 0.59 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.27 Beta-prop_NOL10_N 131 phtmrslayhpytaellsggtsheifrlsletgafvesyktqsasginhvevfknhglimcagadgvveawdsragscasrl 212 h l+ y + +g + i +tg++++++ t + gi + f + +i+ d + w r+ +ca l FUN_000437-T1 418 GHKNNVLTVCGYKNFIATGSLDRTIKVWDANTGTLIQTF-TGHTRGIWSIR-FLSKSIIISGSYDKTIRLWSLRTKACARIL 497 566666777777777778888888888889999999998.55678998887.667789999999***********9999655 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00071 Beta-prop_NOL10_N 66 vsgdypprlkcfdvnqlsmkysfnadmpilggvslspdfrkfalrgeg.rqitvhh..saaiidrvrvph.tmrslayhpytaellsggtsh 153 +sg k +++ q + +s+ + v l d k a+ g g r + v s + v + t +++ y ++ g+ FUN_000437-T1 515 ISGSSDKTAKLWNIRQCKLLFSLVGHNGCVFCVDLD-DTCKRAFSGSGdRTVRVWDvsSGICLSSFNVGQsTDCTVTTVSYDHGYVAVGSGT 605 566666666666666666666666666666666664.4444555555434455543112233445555431333444455555555555555 PP Beta-prop_NOL10_N 154 eifrlsletgafvesyktqsa..s..gin..hvevfknhglimcagadgvveawdsragscasrl 212 + l tg v + + ++ v+ k+ gli+ +g dg+++ wd sc l FUN_000437-T1 606 MVSLWNLTTGDCVHEFSGHKNrvEcvKLKfmMVNGKKEAGLIVSSGKDGLIKYWDIEQASCIQTL 670 555566677777766543322002012221146667999**********************8766 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.32 2e+02 82 140 .. 434 490 .. 424 510 .. 0.74 2 ? 6.1 0.3 0.01 6.4 65 119 .. 540 594 .. 529 638 .. 0.85 3 ? 0.0 0.0 0.71 4.5e+02 86 119 .. 652 692 .. 638 700 .. 0.67 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.32 Beta-prop_VPS8 82 laGyarGqilmwDlsngkllrtisdahppgtavlhikFtddptlalvs.DsgGsvFelsf 140 ++G + +i +wD ++g l++t + h +++ i+F++++ ++ s D+ ++l+ FUN_000437-T1 434 ATGSLDRTIKVWDANTGTLIQTFTG-H--TRGIWSIRFLSKSIIISGSyDKTIRLWSLRT 490 5566666899*********999874.3..4568888988887766666666666666554 PP == domain 2 score: 6.1 bits; conditional E-value: 0.01 Beta-prop_VPS8 65 eqgaVsalafnadstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikF 119 ++g V +++++ ++ r G + ++++wD+s+g +l + + + ++ +v +++ FUN_000437-T1 540 HNGCVFCVDLDDTCKRAFSGSGDRTVRVWDVSSGICLSSFNVGQSTDCTVTTVSY 594 689999*******************************999999999999988887 PP == domain 3 score: 0.0 bits; conditional E-value: 0.71 Beta-prop_VPS8 86 arGqilmwDlsngkllrti.......sdahppgtavlhikF 119 ++G i wD++++++++t+ +++h t ++ ++F FUN_000437-T1 652 KDGLIKYWDIEQASCIQTLrghrdnvNSIHVDSTRIISVSF 692 5799*********8887761111111344445555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (703 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 671 (0.0262674); expected 510.9 (0.02) Passed bias filter: 508 (0.0198865); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 41 (0.00160501); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 40 [number of targets reported over threshold] # CPU time: 0.55u 0.38s 00:00:00.93 Elapsed: 00:00:00.45 # Mc/sec: 6337.99 // Query: FUN_000438-T1 [L=358] Description: FUN_000438 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 2.1 7.7 5.4 3.1 7.2 5.4 1.2 1 Tox-ODYAM1 Toxin in Odyssella and Amoebophilus Domain annotation for each model (and alignments): >> Tox-ODYAM1 Toxin in Odyssella and Amoebophilus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 5.4 0.00012 3.1 90 164 .. 22 98 .. 17 109 .. 0.83 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.00012 Tox-ODYAM1 90 slkklqqkvnaaygsevlkldrgrlernyeerrkevtt..syqkkeeelekkkedisaklkvakhlrvelkkkeddl 164 sl l++ ++++y++e +kl++ + + + +err+++ +++ +e+e+k+++i+++ + ++ r + k+k + + FUN_000438-T1 22 SLLSLRKALHESYQNESFKLKERQRQSMARERREQMENdrIIRNRMKEIEEKEKEITQRYQYLRNWRAKAKRKAAAM 98 8999*******************9999999999998752256889999*999999**99998888888888877654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (358 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1964 (0.0768839); expected 510.9 (0.02) Passed bias filter: 562 (0.0220004); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3478.51 // Query: FUN_000439-T1 [L=635] Description: FUN_000439 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-25 88.5 2.7 2.5e-11 44.2 0.1 2.5 2 Methyltransf_32 Methyltransferase domain 6.2e-06 27.3 0.0 1.6e-05 26.0 0.0 1.7 1 Methyltransf_25 Methyltransferase domain 5.4e-05 23.5 0.0 0.00014 22.1 0.0 1.7 1 Methyltransf_31 Methyltransferase domain 0.00011 22.5 0.0 0.00044 20.5 0.0 2.0 2 Methyltransf_23 Methyltransferase domain 0.00031 21.8 0.0 0.00088 20.4 0.0 1.8 1 Methyltransf_11 Methyltransferase domain 0.0049 18.0 0.0 0.051 14.8 0.0 2.4 2 Methyltransf_12 Methyltransferase domain 0.0089 16.1 0.1 0.017 15.1 0.1 1.4 1 DOT1 Histone methylation protein DOT1 ------ inclusion threshold ------ 0.018 15.1 0.0 0.033 14.2 0.0 1.4 1 MTS Methyltransferase small domain 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 CMAS Mycolic acid cyclopropane synthetase 0.18 12.1 0.0 0.31 11.2 0.0 1.3 1 PCMT Protein-L-isoaspartate(D-aspartate) O-methyl Domain annotation for each model (and alignments): >> Methyltransf_32 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.1 0.4 1e-14 2.7e-11 1 92 [. 128 211 .. 128 268 .. 0.82 2 ! 44.2 0.1 9.6e-15 2.5e-11 83 143 .] 393 454 .. 311 454 .. 0.85 Alignments for each domain: == domain 1 score: 44.1 bits; conditional E-value: 1e-14 Methyltransf_32 1 kKlkqverlaelvekllkevlkekeeltlvDvGaGkgYLgfilydllkekelkvrvlgidvreelvekaeelaeklg..fekrlsfaelsvaea 92 kK +ve ++ ++++l ++ + +++D+G+GkgYL++ l+ +++++v+g+d ++ ++e+a++++ekl + + l ++++++++ FUN_000439-T1 128 KKSYEVEVMSDVINTLATQ----FHVRQILDLGSGKGYLSQNLAL-----QYGLKVIGVDSSQGNTENANKRNEKLLkaW-TGLVKKSQKTEHV 211 7899999999999998888....58899*****************.....*************************98766.5555555555444 PP == domain 2 score: 44.2 bits; conditional E-value: 9.6e-15 Methyltransf_32 83 sfaelsvaeateskeeeekvdvviaLHaCdtatddalrlala.kqakalvlvpCCqaelaeq 143 ++ + ++++++++ e++ +++++LHaC+++ + +lr+++ +k++++v+CC++ +++q FUN_000439-T1 393 RKLFDQLESSDRESSLESNGMFLVGLHACGDLVPMTLRIFVGePSVKLMCIVGCCYHLVSQQ 454 44444555555566889999**********************9***************9986 PP >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.0 6.1e-09 1.6e-05 1 43 [. 152 193 .. 152 213 .. 0.91 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 6.1e-09 Methyltransf_25 1 vLdlGcGtGrlalelakrlgeaevtgvDlseemlerareraae 43 +LdlG G G+l++ la ++g +v+gvD s+ e a++r+++ FUN_000439-T1 152 ILDLGSGKGYLSQNLALQYG-LKVIGVDSSQGNTENANKRNEK 193 8******************9.*******************965 PP >> Methyltransf_31 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.6e-08 0.00014 6 51 .. 151 194 .. 149 217 .. 0.90 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.6e-08 Methyltransf_31 6 kvLDlGCGtGrlsfelaeelgpnaevvGiDiseeaiekArenaekl 51 ++LDlG+G+G+ls++la +v+G+D s+ e+A+++ ekl FUN_000439-T1 151 QILDLGSGKGYLSQNLAL--QYGLKVIGVDSSQGNTENANKRNEKL 194 69***************4..34579***************998875 PP >> Methyltransf_23 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 1.7e-07 0.00044 7 61 .. 134 193 .. 128 230 .. 0.80 2 ? -2.2 0.0 1.7 4.3e+03 33 80 .. 363 412 .. 362 449 .. 0.81 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 1.7e-07 Methyltransf_23 7 reladlllrllpklkspgrvLDiGcGtGiflell.reegfkvvgvDpspeaiera.....n 61 + ++d ++ l++ ++ + +LD+G+G+G+++++l + g kv+gvD s ++e a + FUN_000439-T1 134 EVMSDVINTLAT-QFHVRQILDLGSGKGYLSQNLaLQYGLKVIGVDSSQGNTENAnkrneK 193 567888998875.9********************555588********9999887444440 PP == domain 2 score: -2.2 bits; conditional E-value: 1.7 Methyltransf_23 33 tGiflellreegf.kvv.gvDpspeaieranlknvvkkqfdeeeaaepag 80 G+f+ r++ f +v+ vD s++a++ +++ +++ + d+e+ e++g FUN_000439-T1 363 VGNFCGPSRQNSFlPVTgFVDQSFVANGELRKLFDQLESSDRESSLESNG 412 58888888888888888788999999998877777777777776666655 PP >> Methyltransf_11 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.0 3.4e-07 0.00088 1 40 [. 153 193 .. 153 214 .. 0.90 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 3.4e-07 Methyltransf_11 1 LdvGcGtGllaeala.rlgarvtgvDlspemlelakekakk 40 Ld+G+G+G+l++ la ++g +v+gvD s+ e+a+++++k FUN_000439-T1 153 LDLGSGKGYLSQNLAlQYGLKVIGVDSSQGNTENANKRNEK 193 8**************8888****************999876 PP >> Methyltransf_12 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.79 2e+03 20 79 .. 87 144 .. 76 151 .. 0.72 2 ! 14.8 0.0 2e-05 0.051 1 42 [. 153 193 .. 153 244 .. 0.85 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.79 Methyltransf_12 20 gleyvgvDispaaleaarerlaalerldaarveleqldlaeeepesfDvvvasnvlhhla 79 l+ +++ s+++l+ + ++++l++++v++ ++s+ v v+s+v+ la FUN_000439-T1 87 SLKQFLTEASQNQLKSFSWLKGKQGFLSHDKVHFVSHIMN-P-KKSYEVEVMSDVINTLA 144 4777888889999988888888888888888888877654.2.22999999999998875 PP == domain 2 score: 14.8 bits; conditional E-value: 2e-05 Methyltransf_12 1 LeiGcGtGallrallealpgleyvgvDispaaleaarerlaa 42 L++G+G G+l+++l+ + gl+++gvD s+ e+a++r + FUN_000439-T1 153 LDLGSGKGYLSQNLALQ-YGLKVIGVDSSQGNTENANKRNEK 193 8*************999.9**************877777655 PP >> DOT1 Histone methylation protein DOT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.1 6.8e-06 0.017 29 110 .. 134 213 .. 129 225 .. 0.74 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 6.8e-06 DOT1 29 eflsevldkvnlk.kedvFvDLGSGvGnvvlqaalevgcklsvGvEimdnaselaekqkeelkkrlklfGkklakiefirksF 110 e++s+v++ + + + +DLGSG G + al++g+k +Gv+ ++ +e a+k++e l k + + kk +k+e+ +F FUN_000439-T1 134 EVMSDVINTLATQfHVRQILDLGSGKGYLSQNLALQYGLK-VIGVDSSQGNTENANKRNEKLLKAWTGLVKKSQKTEH--VQF 213 55666666665552335689********************.9*******99999998887777655544455555544..445 PP >> MTS Methyltransferase small domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 1.3e-05 0.033 24 73 .. 140 189 .. 134 212 .. 0.80 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.3e-05 MTS 24 letleke.lsgkvlDlGcGaGvlglalakespeaevtlvdvnarAvesare 73 ++tl ++ + +++lDlG+G G+l+ +la ++ +v vd ++ e a++ FUN_000439-T1 140 INTLATQfHVRQILDLGSGKGYLSQNLALQYGL-KVIGVDSSQGNTENANK 189 57788887889*****************98775.78888888776666654 PP >> CMAS Mycolic acid cyclopropane synthetase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 1.6e-05 0.042 65 107 .. 151 193 .. 140 207 .. 0.91 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.6e-05 CMAS 65 tlLdiGcGWGslvrraverydvkvvglTlSkeqaklakkrvde 107 ++Ld+G G G+l ++ + +y+ kv+g+ S+ +++ a+kr ++ FUN_000439-T1 151 QILDLGSGKGYLSQNLALQYGLKVIGVDSSQGNTENANKRNEK 193 79*****************************999999998665 PP >> PCMT Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00012 0.31 72 121 .. 147 194 .. 121 222 .. 0.79 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00012 PCMT 72 kkgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakknlkkl 121 ++ ++L++GsG Gyl+ la g +v++++ ++ +e+a+k+ +kl FUN_000439-T1 147 FHVRQILDLGSGKGYLSQNLALQYG--LKVIGVDSSQGNTENANKRNEKL 194 46789************99986555..567*******9999999987765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (635 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1077 (0.0421609); expected 510.9 (0.02) Passed bias filter: 788 (0.0308475); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.39u 0.42s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 5954.03 // Query: FUN_000439-T2 [L=501] Description: FUN_000439 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-25 89.5 2.7 1.7e-11 44.8 0.1 2.5 2 Methyltransf_32 Methyltransferase domain 4.4e-06 27.8 0.0 1.1e-05 26.5 0.0 1.7 1 Methyltransf_25 Methyltransferase domain 3.7e-05 24.0 0.0 9.8e-05 22.6 0.0 1.8 1 Methyltransf_31 Methyltransferase domain 6.7e-05 23.1 0.0 0.00031 21.0 0.0 2.1 2 Methyltransf_23 Methyltransferase domain 0.00022 22.3 0.0 0.00064 20.8 0.0 1.8 1 Methyltransf_11 Methyltransferase domain 0.0029 18.8 0.0 0.037 15.2 0.0 2.4 2 Methyltransf_12 Methyltransferase domain 0.0061 16.6 0.1 0.012 15.6 0.1 1.5 1 DOT1 Histone methylation protein DOT1 ------ inclusion threshold ------ 0.013 15.6 0.0 0.024 14.7 0.0 1.4 1 MTS Methyltransferase small domain 0.016 15.1 0.1 0.031 14.1 0.1 1.4 1 CMAS Mycolic acid cyclopropane synthetase 0.079 13.4 0.0 0.18 12.2 0.0 1.6 1 FtsJ FtsJ-like methyltransferase 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 PCMT Protein-L-isoaspartate(D-aspartate) O-methyl Domain annotation for each model (and alignments): >> Methyltransf_32 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.6 0.5 8e-15 1.9e-11 1 92 [. 128 211 .. 128 282 .. 0.83 2 ! 44.8 0.1 7.1e-15 1.7e-11 83 143 .] 393 454 .. 304 454 .. 0.85 Alignments for each domain: == domain 1 score: 44.6 bits; conditional E-value: 8e-15 Methyltransf_32 1 kKlkqverlaelvekllkevlkekeeltlvDvGaGkgYLgfilydllkekelkvrvlgidvreelvekaeelaeklg..fekrlsfaelsvaea 92 kK +ve ++ ++++l ++ + +++D+G+GkgYL++ l+ +++++v+g+d ++ ++e+a++++ekl + + l ++++++++ FUN_000439-T2 128 KKSYEVEVMSDVINTLATQ----FHVRQILDLGSGKGYLSQNLAL-----QYGLKVIGVDSSQGNTENANKRNEKLLkaW-TGLVKKSQKTEHV 211 7899999999999998888....58899*****************.....*************************98766.5555555555444 PP == domain 2 score: 44.8 bits; conditional E-value: 7.1e-15 Methyltransf_32 83 sfaelsvaeateskeeeekvdvviaLHaCdtatddalrlala.kqakalvlvpCCqaelaeq 143 ++ + ++++++++ e++ +++++LHaC+++ + +lr+++ +k++++v+CC++ +++q FUN_000439-T2 393 RKLFDQLESSDRESSLESNGMFLVGLHACGDLVPMTLRIFVGePSVKLMCIVGCCYHLVSQQ 454 44444455555556899999**********************9***************9986 PP >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.0 4.9e-09 1.1e-05 1 43 [. 152 193 .. 152 213 .. 0.91 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 4.9e-09 Methyltransf_25 1 vLdlGcGtGrlalelakrlgeaevtgvDlseemlerareraae 43 +LdlG G G+l++ la ++g +v+gvD s+ e a++r+++ FUN_000439-T2 152 ILDLGSGKGYLSQNLALQYG-LKVIGVDSSQGNTENANKRNEK 193 8******************9.*******************965 PP >> Methyltransf_31 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 4.2e-08 9.8e-05 6 51 .. 151 194 .. 149 244 .. 0.92 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 4.2e-08 Methyltransf_31 6 kvLDlGCGtGrlsfelaeelgpnaevvGiDiseeaiekArenaekl 51 ++LDlG+G+G+ls++la +v+G+D s+ e+A+++ ekl FUN_000439-T2 151 QILDLGSGKGYLSQNLAL--QYGLKVIGVDSSQGNTENANKRNEKL 194 69***************4..34579***************998775 PP >> Methyltransf_23 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 1.3e-07 0.00031 7 61 .. 134 193 .. 128 231 .. 0.80 2 ? -1.7 0.0 1.3 2.9e+03 33 80 .. 363 412 .. 362 450 .. 0.80 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1.3e-07 Methyltransf_23 7 reladlllrllpklkspgrvLDiGcGtGiflell.reegfkvvgvDpspeaiera.....n 61 + ++d ++ l++ ++ + +LD+G+G+G+++++l + g kv+gvD s ++e a + FUN_000439-T2 134 EVMSDVINTLAT-QFHVRQILDLGSGKGYLSQNLaLQYGLKVIGVDSSQGNTENAnkrneK 193 567888998885.9********************555588********9999887444440 PP == domain 2 score: -1.7 bits; conditional E-value: 1.3 Methyltransf_23 33 tGiflellreegf.kvv.gvDpspeaieranlknvvkkqfdeeeaaepag 80 G+f+ r++ f +v+ vD s++a++ +++ +++ + d+e+ e++g FUN_000439-T2 363 VGNFCGPSRQNSFlPVTgFVDQSFVANGELRKLFDQLESSDRESSLESNG 412 58888888888888888788999999998877777777777777666665 PP >> Methyltransf_11 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 2.8e-07 0.00064 1 40 [. 153 193 .. 153 214 .. 0.90 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 2.8e-07 Methyltransf_11 1 LdvGcGtGllaeala.rlgarvtgvDlspemlelakekakk 40 Ld+G+G+G+l++ la ++g +v+gvD s+ e+a+++++k FUN_000439-T2 153 LDLGSGKGYLSQNLAlQYGLKVIGVDSSQGNTENANKRNEK 193 8**************8888****************999876 PP >> Methyltransf_12 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.57 1.3e+03 20 79 .. 87 144 .. 76 152 .. 0.72 2 ! 15.2 0.0 1.6e-05 0.037 1 42 [. 153 193 .. 153 244 .. 0.85 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.57 Methyltransf_12 20 gleyvgvDispaaleaarerlaalerldaarveleqldlaeeepesfDvvvasnvlhhla 79 l+ +++ s+++l+ + ++++l++++v++ ++s+ v v+s+v+ la FUN_000439-T2 87 SLKQFLTEASQNQLKSFSWLKGKQGFLSHDKVHFVSHIMN-P-KKSYEVEVMSDVINTLA 144 4777888889999988888888888888888888877654.2.22999999999998885 PP == domain 2 score: 15.2 bits; conditional E-value: 1.6e-05 Methyltransf_12 1 LeiGcGtGallrallealpgleyvgvDispaaleaarerlaa 42 L++G+G G+l+++l+ + gl+++gvD s+ e+a++r + FUN_000439-T2 153 LDLGSGKGYLSQNLALQ-YGLKVIGVDSSQGNTENANKRNEK 193 8*************999.9**************877777655 PP >> DOT1 Histone methylation protein DOT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.1 5.3e-06 0.012 29 110 .. 134 213 .. 129 225 .. 0.74 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 5.3e-06 DOT1 29 eflsevldkvnlk.kedvFvDLGSGvGnvvlqaalevgcklsvGvEimdnaselaekqkeelkkrlklfGkklakiefirksF 110 e++s+v++ + + + +DLGSG G + al++g+k +Gv+ ++ +e a+k++e l k + + kk +k+e+ +F FUN_000439-T2 134 EVMSDVINTLATQfHVRQILDLGSGKGYLSQNLALQYGLK-VIGVDSSQGNTENANKRNEKLLKAWTGLVKKSQKTEH--VQF 213 55666666665552335689********************.9*******99999998888777655544455555544..445 PP >> MTS Methyltransferase small domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 1e-05 0.024 24 73 .. 140 189 .. 134 212 .. 0.80 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1e-05 MTS 24 letleke.lsgkvlDlGcGaGvlglalakespeaevtlvdvnarAvesare 73 ++tl ++ + +++lDlG+G G+l+ +la ++ +v vd ++ e a++ FUN_000439-T2 140 INTLATQfHVRQILDLGSGKGYLSQNLALQYGL-KVIGVDSSQGNTENANK 189 57788887889*****************98775.78888888776666654 PP >> CMAS Mycolic acid cyclopropane synthetase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.1 1.3e-05 0.031 65 107 .. 151 193 .. 139 207 .. 0.91 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.3e-05 CMAS 65 tlLdiGcGWGslvrraverydvkvvglTlSkeqaklakkrvde 107 ++Ld+G G G+l ++ + +y+ kv+g+ S+ +++ a+kr ++ FUN_000439-T2 151 QILDLGSGKGYLSQNLALQYGLKVIGVDSSQGNTENANKRNEK 193 79*****************************999999998665 PP >> FtsJ FtsJ-like methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 7.7e-05 0.18 22 59 .. 149 186 .. 136 238 .. 0.81 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 7.7e-05 FtsJ 22 gkvvlDlGaapGgfsqvllervgagkvvavDlgpgql.e 59 + +lDlG+++G sq l+ + kv++vD +g+ + FUN_000439-T2 149 VRQILDLGSGKGYLSQNLALQ-YGLKVIGVDSSQGNTeN 186 4679*************9999.56********8886643 PP >> PCMT Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 9.7e-05 0.22 72 121 .. 147 194 .. 121 222 .. 0.78 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 9.7e-05 PCMT 72 kkgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakknlkkl 121 ++ ++L++GsG Gyl+ la g +v++++ ++ +e+a+k+ +kl FUN_000439-T2 147 FHVRQILDLGSGKGYLSQNLALQYG--LKVIGVDSSQGNTENANKRNEKL 194 46789************99986555..567*******9999999987765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (501 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1152 (0.0450969); expected 510.9 (0.02) Passed bias filter: 807 (0.0315913); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.43 # Mc/sec: 4737.79 // Query: FUN_000440-T1 [L=2278] Description: FUN_000440 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-227 758.4 13.0 1e-227 758.4 13.0 1.4 2 ACC_central Acetyl-CoA carboxylase, central region 6.7e-160 533.4 0.0 9.4e-160 532.9 0.0 1.2 1 Carboxyl_trans Carboxyl transferase domain 4.5e-53 180.4 0.0 1.1e-52 179.2 0.0 1.6 1 CPSase_L_D2 Carbamoyl-phosphate synthase L chain, ATP bi 3.7e-37 127.3 0.1 1.7e-36 125.2 0.0 2.1 2 ACCA_BT Acetyl-CoA carboxylase, BT domain 1.1e-30 106.9 0.2 3e-30 105.4 0.0 2.0 2 Biotin_carb_N Biotin carboxylase, N-terminal domain 1.1e-23 83.9 0.0 5.8e-23 81.5 0.0 2.2 2 Biotin_carb_C Biotin carboxylase C-terminal domain 1.2e-12 48.0 0.1 3.6e-12 46.4 0.1 1.9 1 Biotin_lipoyl Biotin-requiring enzyme 0.0024 17.9 0.0 0.007 16.4 0.0 1.8 1 Dala_Dala_lig_C D-ala D-ala ligase C-terminus 0.0053 16.9 0.0 0.012 15.8 0.0 1.5 1 ATP-grasp ATP-grasp domain ------ inclusion threshold ------ 0.014 15.9 0.0 0.062 13.9 0.0 2.1 1 ATP-grasp_3 ATP-grasp domain Domain annotation for each model (and alignments): >> ACC_central Acetyl-CoA carboxylase, central region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 758.4 13.0 4.1e-231 1e-227 1 726 [] 748 1495 .. 748 1495 .. 0.94 2 ? -3.0 0.0 0.85 2.2e+03 421 465 .. 2060 2105 .. 2058 2147 .. 0.63 Alignments for each domain: == domain 1 score: 758.4 bits; conditional E-value: 4.1e-231 ACC_central 1 eLDDpskVkkAkpFegqlpelgsptvvgekphqrfaallsileniLaGYd.....nqvkmketlkeLievLrdpeLPylewqeqlsaLsgrlPa 89 eLDDpskV++A+++++q+pe++ ++v+g+++hq+f+ + ++l+ni++GY ++ +++e + L+++L+dp LP+le+qe++s++sgr+P+ FUN_000440-T1 748 ELDDPSKVTQAQLYSEQFPEASGAKVKGTRLHQVFRVARENLQNIMDGYSigephFSRRLEENVSLLMQALKDPALPLLELQEMISSISGRIPP 841 69******************************************************************************************** PP ACC_central 90 klekslrklveraksr..s..aeFPakqlkkllekflaelvkkadrellkatleplvdlverYenGlkahelsvvasLLeeYlevEklFsgekr 179 ++e+s++k +++++s+ s ++FP++q+++++++++a+l+k+ +r++++ +++ +v+lv+rY+nG+++h+++vv sLL++Yl+ E +F+++ + FUN_000440-T1 842 SVEESIKKHLSNYASNitSvlSQFPSQQIANVVDAHAATLTKRVERDAFFLNTQNIVQLVQRYRNGIRGHMKAVVLSLLRQYLQHEVHFNEG-N 934 ****************86489********************988*********************************************955.6 PP ACC_central 180 eedvvlkLRdenkd.dldkVveivlShskvssKnkLvlalLdeikpnkpsssnvakelrevLkkLaeLesketakVaLkArevLiqaalPslee 272 e++v+ LRd++k+ dl+ Vv+ ++Sh++v++Kn+L ++l+d+++ +s +++el+++L++L++L+++e+akVaL+Ar+ L+++++Ps+e FUN_000440-T1 935 FEKCVTLLRDKHKSkDLSPVVHSIFSHASVARKNQLTIMLIDQLC---GRQSGMSDELNHILQELTALNRHENAKVALRARQALLASQQPSYEL 1025 ************9659*****************************...4445699*************************************** PP ACC_central 273 rkaqmesilkssvtessygeskakhrepslevlkelidskytvfDvLpsffahsdewvslaalevYvrraYraYelksikyheeeeeplivewk 366 r++q+es + s ++ +++ + +++++li s++++fD+Lpsff+h++e+v++aalevY+rr+Y+aYel+++ +++ +e+ live++ FUN_000440-T1 1026 RHNQVESLFLSGIDAYGN--------QLASDSFQKLILSDNALFDILPSFFYHANEAVRRAALEVYIRRSYQAYELTTLYHEKLDESVLIVEFQ 1111 ***************886........7789**************************************************************** PP ACC_central 367 Fqlpkshsseksstlstkskeeesvkriasvs.dlsylvkkseeep..lrtGvlvafksledleealskvleelpkakk............... 442 F lp++h ++ + ++ +sk+ + r+ s+s d+ l++++ + +rtGv++af+s+ ++e+++++++++++ a++ FUN_000440-T1 1112 FILPNAHPNRLPLKV-PSSKTVLAMPRVRSLSeDMFDLINHQPALKpcQRTGVMAAFQSMVEFERNFEQIMNRFEPATAeqlspslmarkvgld 1204 *****9998887766.67777777889998873555565544433367**************************7666699***********98 PP ACC_central 443 ....keeseekeeeesksseelinvlnvairdaeesdsdee.llerleeilkelkeeLlaagvrrvTfivgrkegqypkyfTfreerknYeEdk 531 e++ e+++k++ee+i+++n+a++ +++s+ d e +++ e+++++ke L+++g+rr+T+++ +g +p +fTfr+ ++++Ed+ FUN_000440-T1 1205 pvweI---ESRAEHGAKKEEEPIHIINIALKIEKNSK-DIEfQRKMVYEFTQSKKEILKDKGIRRITYLISDCKGMLPWFFTFRA-GEDFQEDS 1293 55421...33344448899************999999.8883556789***********************977***********.79****** PP ACC_central 532 iiRhiEPalafqLELgrLsnfdikpvptenrqihlYeavakese.....tdkRfFvRaivrpgrlrdkistaeyliseaerllldildaLEv.s 619 i+Rh+EPala+qLE++rL+nfd++ +pt n+++hlY + ak+ + td+RfF+R+ivr++++++k++++ey+ +e+e ll++ld+LEv FUN_000440-T1 1294 IYRHLEPALAYQLEINRLRNFDLETIPTTNHNVHLYLGSAKKMSsqsevTDYRFFIRSIVRHSDFITKEASFEYMEKESEIQLLEALDQLEVsF 1387 ******************************************9999**********************************************99 PP ACC_central 620 sikasnsdlnHiflnfvpevnvdpeeveeavagflerfgkRlwrLrVtqaEirivirdsetgkpiplRlvisnvsGyvvkvelYkEvkdek.ge 712 s++ +++d+nHifl+fvp v ++p+++ee++++++ r+g+Rlw+LrV+qaE +++ir + tgk+iplR+++sn sGy++++++Y+Ev+d++ g+ FUN_000440-T1 1388 SESVKRTDCNHIFLHFVPCVIIEPNRIEESIRHIVTRYGRRLWKLRVLQAEMKVTIRLTPTGKKIPLRVFMSNGSGYYLDFNIYREVTDPRtGQ 1481 999******************************************************************************************* PP ACC_central 713 lvfksigkkkgslh 726 +vf+s+g+k+g+ h FUN_000440-T1 1482 IVFESYGQKQGPHH 1495 *******99*9987 PP == domain 2 score: -3.0 bits; conditional E-value: 0.85 ACC_central 421 ksledleealskvleelpkakkkees.eekeeeesksseelinvln 465 k ++ l++++++++++l++a+ ++ ++ e+++++++e+linv + FUN_000440-T1 2060 KAIHRLDTKCQEIIKALTSADLPVKErKTLERQQKEREEQLINVYQ 2105 5566777778888888866665333323333344566777777764 PP >> Carboxyl_trans Carboxyl transferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 532.9 0.0 3.7e-163 9.4e-160 3 492 .. 1596 2147 .. 1594 2148 .. 0.96 Alignments for each domain: == domain 1 score: 532.9 bits; conditional E-value: 3.7e-163 Carboxyl_trans 3 harGkltareridllldpgsFgeledlaehratefglkk.lprdgvvtgsGaviGravevvaqdftvlgGslgpakaekilkaqeeaikt... 91 ++G+++++ ++d+++ +gsF + ed +++ra+e+++++ lp ++++++sGa+iG a+ev+++++++++++ p+k++k+l++ +k+ FUN_000440-T1 1596 CPEGREIIVVANDITVMIGSFAPPEDMLFKRASEMARAQgLPFVYISANSGARIGLAEEVKHHFNVAWNDAHAPEKGFKYLYVTPSDFKKlsa 1688 589**********************************999***************************************88888888888889 PP Carboxyl_trans 92 ............glpliglndsgGa.egriqegveslrgsgkifganskasgvIpqislvtgpcaGggaYlpalgdrvimveetskifltGpd 171 g++++ ++d++G +g gve+l+gsg+i+g+ s a+++I+++slvt++++G+g+Yl++lg+rvi+v++ ++++ltG++ FUN_000440-T1 1689 snsmhaelieddGESRYQITDIIGRdDG---IGVENLKGSGMIAGEMSAAYDDIVTMSLVTCRAVGIGSYLVRLGQRVIQVDN-AHVILTGAR 1777 *************************666...****************************************************.********* PP Carboxyl_trans 172 vvkkvtG.eevtseelgGarqhmtksGvahltaeddeealelirkllsylPkkasnnrepaPivetadevdrseelieivPddakkpydvrev 263 +++kv+G +++ts+ ++G++q+m+++Gv+hl++ dd+ +++ i+k+lsy+Pk ++ p Pi++++d+vdr+ +e+vP+ k+p d+r FUN_000440-T1 1778 ALNKVLGrQVYTSDLQLGGPQIMHNNGVTHLVVRDDFGGIAAIMKWLSYVPKFRNG---PLPIIKPKDPVDRE---VEFVPP--KAPHDPRHF 1862 ***************************************************77777...*************7...9*****..9******** PP Carboxyl_trans 264 iarlvD.............egeFlEikegyAknvvvGfArlgGqpvGvvAnqpk....................veaG.vlfidsaeKaarfi 322 i ++ + +++F E++ g+Ak+vv+G+ArlgG p+Gv+A++++ +aG v+++dsa+K+a++i FUN_000440-T1 1863 ICGAPHpdkpdvwlsgffdKDSFVETLDGWAKTVVCGRARLGGVPMGVIAVETRavevvipadpgnpesdtkiiTQAGqVWYPDSAYKTAQAI 1955 *****99************************************************************************************** PP Carboxyl_trans 323 rlcdaenlPlviladvpGflvGtrqeyggilkhGakllyalaeatvPkitvilr..kayGGayvvmdskilgadlv.fawptariaVlgpega 412 r++++e+lPl+i+a+++Gf++G++++y+ +lk+Ga++++al+e+++P+++++++ +++GGa+vv+d++i+++++ +a++++r++Vl+p+g+ FUN_000440-T1 1956 RDFNKEQLPLIIFANWRGFSGGMKDMYESVLKYGAYIVDALKEYKQPVFIYLPPngELRGGAWVVVDPTINPEAMEmYADQESRGGVLEPAGT 2048 ************************************************************************96648**************** PP Carboxyl_trans 413 veilfrkekaaaemer..................kdlaat....rkqklkeyeeellnpyvaaargfvDavidpsetraklvialeleakkar 483 vei+fr+++ ++ +r + +++++ke+ee+l+n+y++++++f+ ++++p+++++k+vi l++k++r FUN_000440-T1 2049 VEIKFRRKDLVKAIHRldtkcqeiikaltsadlpV----KerktLERQQKEREEQLINVYQQVSVEFAGLHDTPGRMQEKGVITDILKWKESR 2137 ****************8777766666555555553....055559************************************************ PP Carboxyl_trans 484 .klpakkhgn 492 ++++++++ FUN_000440-T1 2138 rFFYWRLRRI 2147 9******985 PP >> CPSase_L_D2 Carbamoyl-phosphate synthase L chain, ATP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 179.2 0.0 4.2e-56 1.1e-52 23 209 .. 218 400 .. 209 402 .. 0.97 Alignments for each domain: == domain 1 score: 179.2 bits; conditional E-value: 4.2e-56 CPSase_L_D2 23 pvetleealavaeeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEvevlrDakgnvitvcerenslq 118 ++++ e +++a++igyPv+ika+ g+GGkG r a+n++e+++ +++ +ae + + v+v k k+ +++Ev++l+D++gn+i ++ r++s+q FUN_000440-T1 218 CIQDVSEGIKIARDIGYPVMIKASEGGGGKGIRKASNDDEFTNFLRQVQAEVP----GSPVFVMKLAKNARHLEVQLLADEYGNAISIFGRDCSVQ 309 478999*******************************************9996....789************************************ PP CPSase_L_D2 119 lrtqksievAPsqtLtdeerqalreaavkvvrelgvvgagtveflldpkskeyyviEvNtRlsvesalaekaTGldlvkeaakialgekLe 209 +r+qk+ie+AP+ +++ +++++e+avk+ + +g+++agtve+l++p+s+ + ++E+N+Rl+ve++ +e++ ++l +++++ia+g++L FUN_000440-T1 310 RRHQKIIEEAPAAIADPDVFKKMEEDAVKLGQLVGYISAGTVEYLYHPESDTFHFLELNPRLQVEHPCTEMVSDINLPAAQLQIAMGIPLY 400 ****************************************************************************************996 PP >> ACCA_BT Acetyl-CoA carboxylase, BT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 125.2 0.0 6.6e-40 1.7e-36 1 119 [. 556 674 .. 556 675 .. 0.99 2 ? -1.9 0.0 1.5 3.9e+03 17 43 .. 1534 1560 .. 1532 1564 .. 0.86 Alignments for each domain: == domain 1 score: 125.2 bits; conditional E-value: 6.6e-40 ACCA_BT 1 DkllavicGavtkahlaseeslaeykkslekGqvpskdllktvfkvdfiyegvkykftvtrssedsytlfingskvevgvrkLsdgglLvlldGks 96 D +l+vicGav+ a++ ++++ ++k++le+Gq++s d l++ +v++i eg+ky ++v++s+++++++ +n s +ev+++++sdgglL++ + +s FUN_000440-T1 556 DAILGVICGAVHIADAGISKRYVNFKSALERGQILSTDSLTNQEDVELINEGIKYILRVSKSGPNTFFVELNDSWTEVEAHRMSDGGLLLSWNESS 651 889********************************************************************************************* PP ACCA_BT 97 htvYlkeeveatrlsvdsktcll 119 ht+Y+keev+++rl++ +ktc++ FUN_000440-T1 652 HTTYMKEEVDSYRLTISGKTCIF 674 *********************98 PP == domain 2 score: -1.9 bits; conditional E-value: 1.5 ACCA_BT 17 aseeslaeykkslekGqvpskdllktv 43 a+++++ e+ + ekG p+kd+lk + FUN_000440-T1 1534 AISNEWMEWANGNEKGANPNKDVLKVT 1560 6778899999**************975 PP >> Biotin_carb_N Biotin carboxylase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.4 0.0 1.2e-33 3e-30 2 110 .] 45 164 .. 44 164 .. 0.97 2 ? -3.7 0.1 9.3 2.4e+04 38 72 .. 869 903 .. 852 905 .. 0.71 Alignments for each domain: == domain 1 score: 105.4 bits; conditional E-value: 1.2e-33 Biotin_carb_N 2 ikkvlianrgeiAvriiravrel.........gietvavysea..daeslhvreadeavelggasaaesYlniekivkaakesgadaihpGyGfls 86 i+kvlian+g +Av+++r++r++ +i++va+++++ +a++++++ ad+ v+++g++++++Y+n+e i+++ak+ ++a++ G+G++s FUN_000440-T1 45 IEKVLIANNGIAAVKCMRSIRRWayelfgnekAIRFVAMVTPEdlKANAEYIKIADQYVPVPGGTNNHNYANVELILDIAKRIPVQAVWAGWGHAS 140 79*****************************************5558899********************************************** PP Biotin_carb_N 87 EnaefaeaveeagiifiGPsaeal 110 En+++++ ++++gi+fiGP+a+a+ FUN_000440-T1 141 ENPKLPDLLSKHGITFIGPPASAM 164 *********************998 PP == domain 2 score: -3.7 bits; conditional E-value: 9.3 Biotin_carb_N 38 eslhvreadeavelggasaaesYlniekivkaake 72 + + v a++a + ++ + +ln ++iv+++++ FUN_000440-T1 869 QIANVVDAHAATLTKRVERDAFFLNTQNIVQLVQR 903 44556666666666677777889999999998875 PP >> Biotin_carb_C Biotin carboxylase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 81.5 0.0 2.3e-26 5.8e-23 2 107 .. 437 543 .. 436 544 .. 0.99 2 ? -1.2 0.0 1.2 3e+03 85 107 .. 1347 1369 .. 1339 1370 .. 0.84 Alignments for each domain: == domain 1 score: 81.5 bits; conditional E-value: 2.3e-26 Biotin_carb_C 2 aRinaEdpeknflPssGkvtelevpegpgvRvdsgveegsevspyyDsllaklivhgetreealerlrraLaelrieG.vktnieflkaileheef 96 Ri++E+p+++f PssG+++el++ + ++v+ + +v ++ +++ Ds++++++++ge+r++a++++ aL+e+ i+G ++t++e+l ++lehe f FUN_000440-T1 437 TRITSENPDEGFKPSSGTIKELTFRSMKNVWGYFSVGADGGLHEFADSQFGHCFAWGEDRDAARRHMVLALKEISIRGdFRTTVEYLIKLLEHEYF 532 6*********************************************************************************************** PP Biotin_carb_C 97 rkgevdtkfle 107 ++++dt++l+ FUN_000440-T1 533 SSNKIDTGWLD 543 *********97 PP == domain 2 score: -1.2 bits; conditional E-value: 1.2 Biotin_carb_C 85 eflkaileheefrkgevdtkfle 107 f+++i++h++f+++e + +++e FUN_000440-T1 1347 FFIRSIVRHSDFITKEASFEYME 1369 5889***********99998887 PP >> Biotin_lipoyl Biotin-requiring enzyme # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.4 0.1 1.4e-15 3.6e-12 2 73 .] 682 747 .. 681 747 .. 0.97 Alignments for each domain: == domain 1 score: 46.4 bits; conditional E-value: 1.4e-15 Biotin_lipoyl 2 eiksPmiGelvkegvvevlvkvGdkVkagqvlaeveamKmemeipapeaGvvkeilvkeGdtvevgdllaki 73 ++sP++G l++ + v +G++V +g++ ae+e+mKm m++ e+G+v++++ + G+ +e g+++ak+ FUN_000440-T1 682 VLRSPSAGRLIH-----FVVDDGGHVFQGEAFAEIEVMKMVMPLLVSESGCVHYVKNP-GAVLEPGSIVAKL 747 589*********.....*****************************************.**********986 PP >> Dala_Dala_lig_C D-ala D-ala ligase C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 2.7e-06 0.007 30 100 .. 227 300 .. 218 370 .. 0.73 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 2.7e-06 Dala_Dala_lig_C 30 kveeklgyPvfVKpareGSSvGvskveseeelkeaieealky..dekvlvEeai.egreievavlgnedlevle 100 k+ +gyPv++K ++ G G+ k+++ +e+++++++ + v+v + ++r +ev +l +e ++ + FUN_000440-T1 227 KIARDIGYPVMIKASEGGGGKGIRKASNDDEFTNFLRQVQAEvpGSPVFVMKLAkNARHLEVQLLADEYGNAIS 300 577899******************************986554226789999998899********977655443 PP >> ATP-grasp ATP-grasp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 4.6e-06 0.012 16 162 .. 219 370 .. 215 373 .. 0.83 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 4.6e-06 ATP-grasp 16 veskeeleeaveelglpvvvKarrlgyDGkGqsvvrseeeleqalealkekerp...vivEefvpfekElsvlvvrsvdGe.vafypvvetvqedg 107 +++ +e ++++++g+pv++Ka+ +g GkG + +++e ++l++++++ +p v v + ++ + l v + G+ ++++ vq++ FUN_000440-T1 219 IQDVSEGIKIARDIGYPVMIKASEGGG-GKGIRKASNDDEFTNFLRQVQAE-VPgspVFVMKLAKNARHLEVQLLADEYGNaISIFGRDCSVQRRH 312 56667788999***************9.******************99775.43466********9999988777777776477888888888888 PP ATP-grasp 108 ilrlsvapaevsek.lqkeaeeiakkiveeLggvGvlgvElF..vkddellvnElapR 162 + apa++ + + k++ee a k+ + +g++ +vE + d + El pR FUN_000440-T1 313 QKIIEEAPAAIADPdVFKKMEEDAVKLGQLVGYISAGTVEYLyhPESDTFHFLELNPR 370 8888888888766559999999999999999999999999773446677889999998 PP >> ATP-grasp_3 ATP-grasp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 2.4e-05 0.062 28 123 .. 230 319 .. 224 373 .. 0.59 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 2.4e-05 ATP-grasp_3 28 eeeekklvvKpvdGaggegvrlveekeedeaaieevivqefieGeslSvsllsdgekalvlsvnrqlidkaeeefvyaGnvtpietelkeevvela 123 ++ +++ +K +G gg+g+r++ +++e ++++ + vq+ ++G+++ v l+++ + l + + + ++ G ++ +++++++e+a FUN_000440-T1 230 RDIGYPVMIKASEGGGGKGIRKASNDDEFTNFLRQ--VQAEVPGSPVFVMKLAKNARHLEVQLLADEYGN---AISIFGRDCSVQ-RRHQKIIEEA 319 5678999***********************99997..9***********999977665555443333332...344444444333.2233333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2278 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 886 (0.0346839); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.66u 0.42s 00:00:01.08 Elapsed: 00:00:00.44 # Mc/sec: 20824.24 // Query: FUN_000441-T1 [L=645] Description: FUN_000441 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.6e-11 42.1 19.0 1.3e-10 41.4 19.0 1.4 1 Ion_trans Ion transport protein 1.5e-07 31.6 15.2 2.8e-07 30.7 15.2 1.4 1 YVC1_C Calcium channel YVC1-like, C-terminal ------ inclusion threshold ------ 0.021 14.7 1.4 0.021 14.7 1.4 2.9 2 PKD_channel Polycystin cation channel Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.4 19.0 1.5e-14 1.3e-10 13 241 .. 296 528 .. 275 530 .. 0.69 Alignments for each domain: == domain 1 score: 41.4 bits; conditional E-value: 1.5e-14 Ion_trans 13 llntvvlaletyfqpeekelklleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil...........ses....k..es 91 +l + +++ t+ + + e+l ++f + ++l ++ ++ kY++++wn +D++++++++++l+l s + + + FUN_000441-T1 296 FLL-CRVCVSTSSIEP----RMEEYLIFIFFCGILLSEYRQFKEAPS--KYFKDMWNYIDLLALIVYIFILVLriaimahgganS-NnrllEiaNY 383 222.223333333333....444888888888888887777777666..************************999988877652.1345422233 PP Ion_trans 92 lsllrvlrll.rllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlf.ggklkkeekewenpdngrtnFdnfgnallwlfq 185 l+++ l l+ r+ ++ l + + +l+ +++r+ +l+ +l+ +++++++f+++ + +gk + ++ +++ + d +++ l+ FUN_000441-T1 384 LYGFDTLLLIlRFSCIVGLSSNFAPLQL---AIFRMCVDLVVILVQFVFIIVAFSVAITKGYvAGKSF--VEHGGEH---AYRIDLLIKVTNDLMW 471 4444444444355555555555555555...9***********************9996666333333..2333444...4445555555555555 PP Ion_trans 186 tlttegwgdilyatldek.gsaiaviyfvlfiilggvlllnlliaviidnfqelter 241 +l++ d++ + ++ + ++++ f+il++++++n+l+a+++ +f+++ ++ FUN_000441-T1 472 SLFGHRGDDVMRDEAADDvSKYVVLTLYFAFLILSTIMMINILVALLTKTFDNASNN 528 555777789999999998888899999*************************98876 PP >> YVC1_C Calcium channel YVC1-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 15.2 3.3e-11 2.8e-07 5 234 .. 294 540 .. 290 563 .. 0.74 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 3.3e-11 YVC1_C 5 llslfvavlve.rsleittlevvfwfwaagymldeivgfneqgfslyiasfwntfdlgilvlllihlalrlygilmpdv.rkhyvanmaydvlaad 98 ++ l+ v v s+e e +++++ +g +l e f+e s y +wn +dl l++ + l lr+ + + + ++a + d FUN_000441-T1 294 FIFLLCRVCVStSSIEPRMEEYLIFIFFCGILLSEYRQFKEA-PSKYFKDMWNYIDLLALIVYIFILVLRIAIMAHGGAnSNNRLLEIANYLYGFD 388 55566666665156788888888888999**********996.599***********99998888888887655444331334556666667788* PP YVC1_C 99 aillfprlfsvldhyryfsplliafrymaadlvavslliliscsgffvaltlsf..gkdgvdtpssvayal..........lqmlmgftpaawdrw 182 ++ll+ r+ ++ f+pl +a+ m+ dlv + + + f va+t + gk v+ ay + + l+g r FUN_000441-T1 389 TLLLILRFSCIVGLSSNFAPLQLAIFRMCVDLVVILVQFVFIIVAFSVAITKGYvaGKSFVEHGGEHAYRIdllikvtndlMWSLFGHRGDDVMRD 484 *********************************999999999999****99765558998988888888641110100000333344444444444 PP YVC1_C 183 neynalgk.tiltl...flfichflvvtilitvltnsfmaivrnaneehqflfavn 234 + + + k +ltl fl++ ++++ il+++lt++f na+ e +f av FUN_000441-T1 485 EAADDVSKyVVLTLyfaFLILSTIMMINILVALLTKTFDNASNNAEIEWKFARAVI 540 55555666346777433677889999********************9999988874 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 1.4 2.5e-06 0.021 15 64 .. 315 364 .. 304 373 .. 0.84 2 ? 0.6 13.9 0.05 4.2e+02 94 223 .. 379 523 .. 372 525 .. 0.83 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.5e-06 PKD_channel 15 vvfvvfvlyfvveeilkirkerasylrsvwnlldlaivvlsvvlivlail 64 ++ +f++ e+ ++++ +y++++wn +dl+ +++ ++++vl+i+ FUN_000441-T1 315 YLIFIFFCGILLSEYRQFKEAPSKYFKDMWNYIDLLALIVYIFILVLRIA 364 55677888888899999999999************999999999999886 PP == domain 2 score: 0.6 bits; conditional E-value: 0.05 PKD_channel 94 qllriilavlvflttlkllkvlrfnktmslltktlaralkdlagf..alvivilflayaqlgvllfGtqasnfsnlvksiltlfrlilgdfqyt.. 185 ++++++ ++ l++l++ ++ +++++ l+ +++r dl+ + +v++i+ ++ a++ + G+ + + l++ + +d+ ++ FUN_000441-T1 379 EIANYLYGFDTLLLILRFSCIVGLSSNFAPLQLAIFRMCVDLVVIlvQFVFIIVAFSVAITKGYVAGKSFVEHGGEHAYRIDLLIKVTNDLMWSlf 474 688999999***************************988887665115667777777788888888888877766666666666677777777777 PP PKD_channel 186 ...........elesgnrvLGpllllalvflvifillnlflaiindsye 223 + + + + l+ a+ +l+ ++++n+++a++ ++++ FUN_000441-T1 475 ghrgddvmrdeAADDVSKYVVLTLYFAFLILSTIMMINILVALLTKTFD 523 777******9989999*****************************9997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (645 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1429 (0.0559405); expected 510.9 (0.02) Passed bias filter: 712 (0.0278724); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6200.35 // Query: FUN_000441-T2 [L=645] Description: FUN_000441 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.6e-11 42.1 19.0 1.3e-10 41.4 19.0 1.4 1 Ion_trans Ion transport protein 1.5e-07 31.6 15.2 2.8e-07 30.7 15.2 1.4 1 YVC1_C Calcium channel YVC1-like, C-terminal ------ inclusion threshold ------ 0.021 14.7 1.4 0.021 14.7 1.4 2.9 2 PKD_channel Polycystin cation channel Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.4 19.0 1.5e-14 1.3e-10 13 241 .. 296 528 .. 275 530 .. 0.69 Alignments for each domain: == domain 1 score: 41.4 bits; conditional E-value: 1.5e-14 Ion_trans 13 llntvvlaletyfqpeekelklleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil...........ses....k..es 91 +l + +++ t+ + + e+l ++f + ++l ++ ++ kY++++wn +D++++++++++l+l s + + + FUN_000441-T2 296 FLL-CRVCVSTSSIEP----RMEEYLIFIFFCGILLSEYRQFKEAPS--KYFKDMWNYIDLLALIVYIFILVLriaimahgganS-NnrllEiaNY 383 222.223333333333....444888888888888887777777666..************************999988877652.1345422233 PP Ion_trans 92 lsllrvlrll.rllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlf.ggklkkeekewenpdngrtnFdnfgnallwlfq 185 l+++ l l+ r+ ++ l + + +l+ +++r+ +l+ +l+ +++++++f+++ + +gk + ++ +++ + d +++ l+ FUN_000441-T2 384 LYGFDTLLLIlRFSCIVGLSSNFAPLQL---AIFRMCVDLVVILVQFVFIIVAFSVAITKGYvAGKSF--VEHGGEH---AYRIDLLIKVTNDLMW 471 4444444444355555555555555555...9***********************9996666333333..2333444...4445555555555555 PP Ion_trans 186 tlttegwgdilyatldek.gsaiaviyfvlfiilggvlllnlliaviidnfqelter 241 +l++ d++ + ++ + ++++ f+il++++++n+l+a+++ +f+++ ++ FUN_000441-T2 472 SLFGHRGDDVMRDEAADDvSKYVVLTLYFAFLILSTIMMINILVALLTKTFDNASNN 528 555777789999999998888899999*************************98876 PP >> YVC1_C Calcium channel YVC1-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 15.2 3.3e-11 2.8e-07 5 234 .. 294 540 .. 290 563 .. 0.74 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 3.3e-11 YVC1_C 5 llslfvavlve.rsleittlevvfwfwaagymldeivgfneqgfslyiasfwntfdlgilvlllihlalrlygilmpdv.rkhyvanmaydvlaad 98 ++ l+ v v s+e e +++++ +g +l e f+e s y +wn +dl l++ + l lr+ + + + ++a + d FUN_000441-T2 294 FIFLLCRVCVStSSIEPRMEEYLIFIFFCGILLSEYRQFKEA-PSKYFKDMWNYIDLLALIVYIFILVLRIAIMAHGGAnSNNRLLEIANYLYGFD 388 55566666665156788888888888999**********996.599***********99998888888887655444331334556666667788* PP YVC1_C 99 aillfprlfsvldhyryfsplliafrymaadlvavslliliscsgffvaltlsf..gkdgvdtpssvayal..........lqmlmgftpaawdrw 182 ++ll+ r+ ++ f+pl +a+ m+ dlv + + + f va+t + gk v+ ay + + l+g r FUN_000441-T2 389 TLLLILRFSCIVGLSSNFAPLQLAIFRMCVDLVVILVQFVFIIVAFSVAITKGYvaGKSFVEHGGEHAYRIdllikvtndlMWSLFGHRGDDVMRD 484 *********************************999999999999****99765558998988888888641110100000333344444444444 PP YVC1_C 183 neynalgk.tiltl...flfichflvvtilitvltnsfmaivrnaneehqflfavn 234 + + + k +ltl fl++ ++++ il+++lt++f na+ e +f av FUN_000441-T2 485 EAADDVSKyVVLTLyfaFLILSTIMMINILVALLTKTFDNASNNAEIEWKFARAVI 540 55555666346777433677889999********************9999988874 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 1.4 2.5e-06 0.021 15 64 .. 315 364 .. 304 373 .. 0.84 2 ? 0.6 13.9 0.05 4.2e+02 94 223 .. 379 523 .. 372 525 .. 0.83 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.5e-06 PKD_channel 15 vvfvvfvlyfvveeilkirkerasylrsvwnlldlaivvlsvvlivlail 64 ++ +f++ e+ ++++ +y++++wn +dl+ +++ ++++vl+i+ FUN_000441-T2 315 YLIFIFFCGILLSEYRQFKEAPSKYFKDMWNYIDLLALIVYIFILVLRIA 364 55677888888899999999999************999999999999886 PP == domain 2 score: 0.6 bits; conditional E-value: 0.05 PKD_channel 94 qllriilavlvflttlkllkvlrfnktmslltktlaralkdlagf..alvivilflayaqlgvllfGtqasnfsnlvksiltlfrlilgdfqyt.. 185 ++++++ ++ l++l++ ++ +++++ l+ +++r dl+ + +v++i+ ++ a++ + G+ + + l++ + +d+ ++ FUN_000441-T2 379 EIANYLYGFDTLLLILRFSCIVGLSSNFAPLQLAIFRMCVDLVVIlvQFVFIIVAFSVAITKGYVAGKSFVEHGGEHAYRIDLLIKVTNDLMWSlf 474 688999999***************************988887665115667777777788888888888877766666666666677777777777 PP PKD_channel 186 ...........elesgnrvLGpllllalvflvifillnlflaiindsye 223 + + + + l+ a+ +l+ ++++n+++a++ ++++ FUN_000441-T2 475 ghrgddvmrdeAADDVSKYVVLTLYFAFLILSTIMMINILVALLTKTFD 523 777******9989999*****************************9997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (645 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1432 (0.0560579); expected 510.9 (0.02) Passed bias filter: 715 (0.0279898); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6243.81 // Query: FUN_000442-T1 [L=356] Description: FUN_000442 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-17 62.2 13.9 7e-17 61.9 13.9 1.1 1 Ion_trans Ion transport protein 6.3e-09 36.1 17.6 0.00028 20.9 0.6 3.2 3 PKD_channel Polycystin cation channel 3.3e-08 33.7 14.3 7.5e-05 22.7 9.3 2.1 2 YVC1_C Calcium channel YVC1-like, C-terminal ------ inclusion threshold ------ 0.75 10.3 7.3 1.1 9.9 0.2 3.1 3 DUF2231 Predicted membrane protein (DUF2231) Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.9 13.9 1.1e-20 7e-17 9 241 .. 8 256 .. 4 258 .. 0.76 Alignments for each domain: == domain 1 score: 61.9 bits; conditional E-value: 1.1e-20 Ion_trans 9 lllillntvvlaletyfqpeekelklleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil............ses...k 89 +++i+l++ +++l+++ +p + e+l l+f + f++ l + ++ + Ylr++wn +D++ +++ ++lil + + FUN_000442-T1 8 FVFIILHIRMCVLDSSVEP-----RIEEYLILIFYIGFLVSELQQYLTSES-RVYLRNMWNYVDLMTLSLHAVILILrvisvvlggdpyH-NrllE 96 6789999999999999999.....899************************.*************************9988877655441.14443 PP Ion_trans 90 eslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkk...eekewenpdngrtnFdn..fgnal 180 ++++ v+ ll +lr+ +++ +++ l +l+r+ +l+ +l+ + +v+++f+++ ++ l + + e +++ n+ F + +l FUN_000442-T1 97 ITHYIYGVNTLLLILRFSSILEANKTVGPLQLALFRMCVDLFIILVQFGFVIVAFSMAITMVYTAELSYgtpPPGERQSNTNKAKGFCQkgTYACL 192 56777777777777777777777777777777***************************8888677776543122333333333334445755555 PP Ion_trans 181 lwlfq.tltte.gwgdilyatldek.gsaiaviyfvlfiilggvlllnlliaviidnfqelter 241 + + + ++ + g +d+ + + +e+ +s + +++vlf+i++ ++l+n+l+a++++++++++ + FUN_000442-T1 193 YKASThLIWSVfGLTDLDEMGSQEQlSSTVVGVLYVLFLIISVIMLVNMLVALLTNTYDKVETN 256 555553333333555554444444477788888*************************998765 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.6 4.4e-08 0.00028 14 64 .. 30 81 .. 21 87 .. 0.90 2 ! 10.7 3.6 5.5e-05 0.35 94 157 .. 96 159 .. 91 165 .. 0.86 3 ! 13.6 0.6 7.5e-06 0.048 192 225 .] 221 253 .. 185 253 .. 0.67 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 4.4e-08 PKD_channel 14 evvfvvfvlyfvveeilkirker.asylrsvwnlldlaivvlsvvlivlail 64 e ++++f + f v e++++ + + ylr++wn +dl+ + l +v+++l+++ FUN_000442-T1 30 EYLILIFYIGFLVSELQQYLTSEsRVYLRNMWNYVDLMTLSLHAVILILRVI 81 56899*************999988***********************99986 PP == domain 2 score: 10.7 bits; conditional E-value: 5.5e-05 PKD_channel 94 qllriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllf 157 +++ +i +v l++l++ +l+ nkt+ l+ +l+r dl+ + + + +++a+ ++ ++++ FUN_000442-T1 96 EITHYIYGVNTLLLILRFSSILEANKTVGPLQLALFRMCVDLFIILVQFGFVIVAFSMAITMVY 159 67899************************************99988888888888877777665 PP == domain 3 score: 13.6 bits; conditional E-value: 7.5e-06 PKD_channel 192 rvLGpllllalvflvifillnlflaiindsyeev 225 v G+l ++++ ++++++l+n+++a++ ++y++v FUN_000442-T1 221 TVVGVL-YVLFLIISVIMLVNMLVALLTNTYDKV 253 355655.678889999***************976 PP >> YVC1_C Calcium channel YVC1-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 9.3 1.2e-08 7.5e-05 12 153 .. 18 160 .. 7 169 .. 0.86 2 ! 13.9 0.2 5.6e-06 0.036 191 238 .. 225 272 .. 197 301 .. 0.82 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 1.2e-08 YVC1_C 12 vlversleittlevvfwfwaagymldeivgfneqgfslyiasfwntfdlgilvlllihlalrlygilm.pdvrkhyvanmaydvlaadaillfprl 106 +++ s+e e ++ ++ g+++ e+ + +y+ ++wn +dl l l + l lr+ +++ d + + ++++ + +++ll+ r+ FUN_000442-T1 18 CVLDSSVEPRIEEYLILIFYIGFLVSELQQYLTSESRVYLRNMWNYVDLMTLSLHAVILILRVISVVLgGDPYHNRLLEITHYIYGVNTLLLILRF 113 345778888888999999999*****************************************99987725777778999***************** PP YVC1_C 107 fsvldhyryfsplliafrymaadlvavslliliscsgffvaltlsfg 153 s+l+ + + pl +a+ m+ dl + + f +a+t+ + FUN_000442-T1 114 SSILEANKTVGPLQLALFRMCVDLFIILVQFGFVIVAFSMAITMVYT 160 ************************98888777778888888887765 PP == domain 2 score: 13.9 bits; conditional E-value: 5.6e-06 YVC1_C 191 tiltlflfichflvvtilitvltnsfmaivrnaneehqflfavntish 238 + lfl+i +++v +l+++ltn++ + na+ e +f av + + FUN_000442-T1 225 VLYVLFLIISVIMLVNMLVALLTNTYDKVETNADVEWKFSRAVVAEEY 272 45689**********************************999876555 PP >> DUF2231 Predicted membrane protein (DUF2231) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.5 0.079 5e+02 17 99 .. 38 122 .. 32 142 .. 0.60 2 ? 9.9 0.2 0.00017 1.1 7 114 .. 140 268 .. 137 270 .. 0.81 3 ? 2.0 0.1 0.043 2.8e+02 5 19 .. 276 290 .. 274 293 .. 0.88 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.079 DUF2231 17 ilallfdiayaltgrpawarvalwllvagavagllaavaGl...idlllaervraakkvallHfvlnvlllalalvntlwRaaart 99 i +l++++ +lt +++ +w+ v + +l a+++ l + +l ++ ++ ++H + +v l+l+l + + +a++t FUN_000442-T1 38 IGFLVSELQQYLTSESRVYLRNMWNYVDLMTLSLHAVILILrviSVVLGGDPYH-NRLLEITHYIYGVNTLLLILRFSSILEANKT 122 566677777777777777777788877777776666665431113333444444.7777777888877777776655555554444 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00017 DUF2231 7 llVhfpiallilallfdiayal................tgrpawarvalwllvagavagllaavaGlidlllaervr.....aakkvallHfvlnv 81 +lV f ++++++++ +++y++ ++ + + + + ++ + a + l+ v+Gl+dl + + l+ ++ v FUN_000442-T1 140 ILVQFGFVIVAFSMAITMVYTAelsygtpppgerqsntNKAKGFCQKGTYACLYKASTHLIWSVFGLTDLDEMGSQEqlsstVVGVLYVLFLIISV 235 6899999999999999999999**************9888999*************************9765544443434344444566778888 PP DUF2231 82 lllalalvntlwRaaarteaalqvplglllslv 114 ++l+ +lv +l +++e + v + + ++v FUN_000442-T1 236 IMLVNMLVALLTNTYDKVETNADVEWKFSRAVV 268 888888888888888888888888888877666 PP == domain 3 score: 2.0 bits; conditional E-value: 0.043 DUF2231 5 HPllVhfpiallila 19 HP++V+f i ++++a FUN_000442-T1 276 HPIIVPFNILTVPIA 290 *********988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (356 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1137 (0.0445097); expected 510.9 (0.02) Passed bias filter: 562 (0.0220004); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3466.50 // Query: FUN_000443-T1 [L=269] Description: FUN_000443 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (269 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1063 (0.0416128); expected 510.9 (0.02) Passed bias filter: 599 (0.0234488); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2630.41 // Query: FUN_000444-T1 [L=78] Description: FUN_000444 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (78 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 626 (0.0245058); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.38s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 814.53 // Query: FUN_000445-T1 [L=157] Description: FUN_000445 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 481 (0.0188295); expected 510.9 (0.02) Passed bias filter: 433 (0.0169505); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1567.79 // Query: FUN_000446-T1 [L=107] Description: FUN_000446 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 306 (0.0119789); expected 510.9 (0.02) Passed bias filter: 277 (0.0108436); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1091.99 // Query: FUN_000447-T1 [L=157] Description: FUN_000447 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 484 (0.018947); expected 510.9 (0.02) Passed bias filter: 435 (0.0170288); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.49 # Mc/sec: 1295.74 // Query: FUN_000448-T1 [L=176] Description: FUN_000448 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-26 91.5 0.0 7.5e-26 91.3 0.0 1.0 1 PRELI PRELI-like family ------ inclusion threshold ------ 0.041 14.0 0.1 0.052 13.6 0.1 1.1 1 IP_trans Phosphatidylinositol transfer protein 0.11 13.0 0.0 0.16 12.4 0.0 1.4 1 Phage_YunG-like Phage YunG-like protein Domain annotation for each model (and alignments): >> PRELI PRELI-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.3 0.0 8.8e-30 7.5e-26 1 152 [. 16 167 .. 16 172 .. 0.92 Alignments for each domain: == domain 1 score: 91.3 bits; conditional E-value: 8.8e-30 PRELI 1 eqVtaaflrkyPnpiskhvisvdvlereldd.egkllteRlitlqvrlPrwlkkligvaktvyvleesvvdpkkrtlkletrNltfskllkveErv 95 e+V++a+++ky +++v++++vle ++d+ +g+ ++ R+ ++ + lP +lkkl + k + v+ee ++++k++ l l Nlt+s++ ++eE + FUN_000448-T1 16 EKVSRAYFQKYTCGKDTNVTAIKVLEHKIDPqTGEEYVLRRGECVNVLPGILKKLCPFGK-IEVEEEAWLNKKEKYLRLHCYNLTWSNYASLEEFS 110 79*****************************99************************888.*********************************** PP PRELI 96 tYkphpensekTvlkqeakisvkgalfglsskveklllkkfsenakkgkeglesvlk 152 ++++ ++n+++T+++q+++isv g ++ + e ++ + ++ a+kg ++e +l FUN_000448-T1 111 CFRAYENNPNWTIFEQRGTISVCGLGSLICGMFESFGHSFLQRGAQKGLGIMEDILL 167 **********************9955556666677776666677*********9985 PP >> IP_trans Phosphatidylinositol transfer protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 6.1e-06 0.052 34 88 .. 29 83 .. 17 104 .. 0.76 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 6.1e-06 IP_trans 34 gkgegvevlknepyedekggkgqyTekiyhlksklPswirallpkkaleveEkaw 88 gk+++v+ +k +++ ++++ +y ++ ++ + lP+++++l+p + +eveE+aw FUN_000448-T1 29 GKDTNVTAIKVLEHKIDPQTGEEYVLRRGECVNVLPGILKKLCPFGKIEVEEEAW 83 44444444444444434555578999***************************** PP >> Phage_YunG-like Phage YunG-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.9e-05 0.16 2 50 .. 37 96 .. 36 117 .. 0.75 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.9e-05 Phage_YunG-like 2 iqkikdifedqvdvsyifknGkCyqla.klLkhvfpeakiv......lskveg....Hvv 50 i+ ++ ++q+ +y++++G+C + +Lk+ p +ki l+k+e+ H++ FUN_000448-T1 37 IKVLEHKIDPQTGEEYVLRRGECVNVLpGILKKLCPFGKIEveeeawLNKKEKylrlHCY 96 5667788899999**********987527***********62333323333335666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (176 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 484 (0.018947); expected 510.9 (0.02) Passed bias filter: 429 (0.0167939); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.34s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1802.03 // Query: FUN_000449-T1 [L=273] Description: FUN_000449 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-11 44.0 0.1 9.3e-07 28.9 0.1 3.2 3 TPR_1 Tetratricopeptide repeat 2.6e-08 33.9 0.2 4.9e-05 23.6 0.1 3.6 3 TPR_2 Tetratricopeptide repeat 2.7e-05 24.5 0.7 0.00021 21.7 0.0 2.8 2 TPR_8 Tetratricopeptide repeat 9.5e-05 22.8 0.1 0.00034 21.1 0.0 1.9 2 TPR_9 Tetratricopeptide repeat 0.001 20.0 0.4 0.011 16.9 0.3 2.4 2 TPR_14 Tetratricopeptide repeat 0.0015 19.2 0.2 1.7 9.4 0.2 3.1 2 TPR_12 Tetratricopeptide repeat 0.0031 18.1 0.2 0.44 11.4 0.0 3.5 3 TPR_17 Tetratricopeptide repeat 0.0033 18.2 0.2 0.011 16.5 0.1 2.0 2 TPR_19 Tetratricopeptide repeat 0.0041 18.0 0.0 0.21 12.5 0.0 2.5 3 TPR_16 Tetratricopeptide repeat ------ inclusion threshold ------ 0.014 16.5 0.4 0.15 13.2 0.1 2.6 2 TPR_6 Tetratricopeptide repeat 0.025 14.5 0.1 0.038 13.9 0.1 1.4 1 SPO22 Meiosis protein SPO22/ZIP4 like 0.035 14.3 0.0 1.6 9.0 0.0 2.9 3 TPR_11 TPR repeat 0.047 14.5 0.6 0.15 12.8 0.6 1.9 1 THOC7 Tho complex subunit 7 0.097 13.4 0.5 0.31 11.7 0.1 2.0 2 FKBP_N_2 BDBT FKBP like N-terminal 0.39 11.4 1.4 2.7 8.7 0.2 2.7 3 Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 2.7 4.6e+03 11 29 .. 130 148 .. 121 149 .. 0.56 2 ! 11.5 0.0 0.00017 0.29 3 34 .] 172 203 .. 170 203 .. 0.92 3 ! 28.9 0.1 5.5e-10 9.3e-07 2 32 .. 205 235 .. 204 235 .. 0.98 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 2.7 TPR_1 11 yfklgkydeAleyyekALe 29 ++k g++ A y++AL+ FUN_000449-T1 130 CYKVGNWLSASRRYSRALK 148 5555554444444666665 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00017 TPR_1 3 alynlGnayfklgkydeAleyyekALelnPnn 34 +l nl+++ kl++++ + + k+L P+n FUN_000449-T1 172 CLLNLAACQGKLEQFEFVAQNCTKVLAMVPSN 203 689***********************998876 PP == domain 3 score: 28.9 bits; conditional E-value: 5.5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALelnP 32 kaly++G+a+ +l+++d+A + ekAL +P FUN_000449-T1 205 KALYRRGQAFVHLNEFDKAKVDLEKALAMDP 235 79****************************9 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.042 72 7 29 .. 126 148 .. 123 150 .. 0.70 2 ? 1.4 0.0 0.4 6.7e+02 3 34 .] 172 203 .. 170 203 .. 0.87 3 ! 23.6 0.1 2.9e-08 4.9e-05 2 32 .. 205 235 .. 204 235 .. 0.97 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.042 TPR_2 7 lGlayyklgdyeeAleayekAle 29 G +yk g++ A + y +Al+ FUN_000449-T1 126 KGTDCYKVGNWLSASRRYSRALK 148 56667777777777777777776 PP == domain 2 score: 1.4 bits; conditional E-value: 0.4 TPR_2 3 alynlGlayyklgdyeeAleayekAleldPnn 34 +l nl+ + kl ++e ++ + k+l+ P n FUN_000449-T1 172 CLLNLAACQGKLEQFEFVAQNCTKVLAMVPSN 203 68899**********99999999999988876 PP == domain 3 score: 23.6 bits; conditional E-value: 2.9e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldP 32 +aly++G+a +l+++++A+ ++ekAl+ dP FUN_000449-T1 205 KALYRRGQAFVHLNEFDKAKVDLEKALAMDP 235 69***************************99 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 3.1 5.4e+03 22 29 .. 57 64 .. 54 64 .. 0.83 2 ! 21.7 0.0 1.3e-07 0.00021 2 32 .. 205 235 .. 204 236 .. 0.96 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 3.1 TPR_8 22 eyyekale 29 e++ek+le FUN_000449-T1 57 ETLEKCLE 64 899***97 PP == domain 2 score: 21.7 bits; conditional E-value: 1.3e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +a+y++G++ l+++++Ak +ekal +dp FUN_000449-T1 205 KALYRRGQAFVHLNEFDKAKVDLEKALAMDP 235 79***************************99 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 2.8 4.7e+03 4 15 .. 136 147 .. 131 159 .. 0.60 2 ! 21.1 0.0 2e-07 0.00034 21 70 .. 196 246 .. 183 249 .. 0.85 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 2.8 TPR_9 4 iyireedleral 15 ++ +++++ ral FUN_000449-T1 136 WLSASRRYSRAL 147 444444444444 PP == domain 2 score: 21.1 bits; conditional E-value: 2e-07 TPR_9 21 llllaPddpeerrdrGllyaqlgcleaAladLeaylalap.dapdaeaire 70 +l++ P ++ rG++ ++l+ + +A dLe++la++p +++ e++r+ FUN_000449-T1 196 VLAMVPSNLKALYRRGQAFVHLNEFDKAKVDLEKALAMDPcNRAVQEQLRA 246 67888999999999**************************87777777766 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.9 3.3e+03 15 30 .. 134 149 .. 128 152 .. 0.58 2 ! 16.9 0.3 6.3e-06 0.011 2 41 .. 205 244 .. 204 246 .. 0.93 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.9 TPR_14 15 GdpdeAlelleralal 30 G++ A + + ral++ FUN_000449-T1 134 GNWLSASRRYSRALKQ 149 4444555555555543 PP == domain 2 score: 16.9 bits; conditional E-value: 6.3e-06 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlal 41 +a++++++a++ l+++d+A le+ala dP +++++++l FUN_000449-T1 205 KALYRRGQAFVHLNEFDKAKVDLEKALAMDPCNRAVQEQL 244 6899*****************************9998765 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.016 27 44 73 .. 119 148 .. 104 157 .. 0.61 2 ! 9.4 0.2 0.00098 1.7 44 75 .. 203 234 .. 169 235 .. 0.72 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.016 TPR_12 44 tatalrnLgrlylalgdyeeAlelleqale 73 a+ + + g+ +++ g++ +A +++ +al+ FUN_000449-T1 119 IARHHKTKGTDCYKVGNWLSASRRYSRALK 148 455555555555555555555555555554 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00098 TPR_12 44 tatalrnLgrlylalgdyeeAlelleqaleia 75 + al+ g+++ l+++++A le+al+++ FUN_000449-T1 203 NLKALYRRGQAFVHLNEFDKAKVDLEKALAMD 234 477999***********************996 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.9 1.5e+03 15 29 .. 172 186 .. 168 187 .. 0.83 2 ! 11.4 0.0 0.00026 0.44 2 33 .. 193 224 .. 192 225 .. 0.95 3 ? 1.4 0.0 0.42 7.2e+02 3 12 .. 228 237 .. 227 237 .. 0.88 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.9 TPR_17 15 ayynLArlllnnGql 29 ++ nLA ++ ++ q+ FUN_000449-T1 172 CLLNLAACQGKLEQF 186 789*****9998886 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00026 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 ++k+l++ P n +a+y ++++ +++++++A+ FUN_000449-T1 193 CTKVLAMVPSNLKALYRRGQAFVHLNEFDKAK 224 789**************************995 PP == domain 3 score: 1.4 bits; conditional E-value: 0.42 TPR_17 3 lkaleldPnn 12 +kal++dP n FUN_000449-T1 228 EKALAMDPCN 237 8*******87 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 6.7 1.1e+04 38 49 .. 140 151 .. 137 159 .. 0.60 2 ! 16.5 0.1 6.7e-06 0.011 12 62 .. 191 241 .. 182 248 .. 0.87 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 6.7 TPR_19 38 lgrldeAealLa 49 + r+++A + L FUN_000449-T1 140 SRRYSRALKQLI 151 456666666655 PP == domain 2 score: 16.5 bits; conditional E-value: 6.7e-06 TPR_19 12 alLeqalaedPdnaearllLArallalgrldeAealLaalpaadpddpeya 62 + ++++la+ P n a+++ ++a ++l+++d+A+ L++++a dp + +++ FUN_000449-T1 191 QNCTKVLAMVPSNLKALYRRGQAFVHLNEFDKAKVDLEKALAMDPCNRAVQ 241 77899*****************************99999999998766665 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.19 3.2e+02 5 26 .. 128 149 .. 125 151 .. 0.83 2 ! 12.5 0.0 0.00012 0.21 23 55 .. 196 229 .. 190 235 .. 0.82 3 ! 8.6 0.1 0.0021 3.6 1 33 [. 208 239 .. 208 247 .. 0.91 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.19 TPR_16 5 raalaagdyddAaaaleaalrr 26 ++ ++ g++ A +++ +al++ FUN_000449-T1 128 TDCYKVGNWLSASRRYSRALKQ 149 55578899999999**999985 PP == domain 2 score: 12.5 bits; conditional E-value: 0.00012 TPR_16 23 alrrnPeaaaAllglGlallrqgrlaeAa.aayr 55 +l++ P++ Al+++G+a+ +++++++A ++ + FUN_000449-T1 196 VLAMVPSNLKALYRRGQAFVHLNEFDKAKvDLEK 229 78999**********************9655544 PP == domain 3 score: 8.6 bits; conditional E-value: 0.0021 TPR_16 1 lalaraalaagdyddAaaaleaalrrnPeaaaA 33 +++++a++ ++++d A le al+++P +++A FUN_000449-T1 208 YRRGQAFVHLNEFDKAKVDLEKALAMDP-CNRA 239 789************************9.8887 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 1.4 2.4e+03 2 15 .. 172 185 .. 171 187 .. 0.81 2 ? 13.2 0.1 9e-05 0.15 2 28 .. 206 232 .. 205 235 .. 0.91 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1.4 TPR_6 2 Allklalsylelgd 15 +ll+la ++ +l + FUN_000449-T1 172 CLLNLAACQGKLEQ 185 699******99855 PP == domain 2 score: 13.2 bits; conditional E-value: 9e-05 TPR_6 2 AllklalsylelgdkdeAkaalqrlik 28 Al++ ++++ l+++d+Ak l++ ++ FUN_000449-T1 206 ALYRRGQAFVHLNEFDKAKVDLEKALA 232 9*********************99876 PP >> SPO22 Meiosis protein SPO22/ZIP4 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.1 2.3e-05 0.038 38 111 .. 130 197 .. 120 253 .. 0.87 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 2.3e-05 SPO22 38 lYnigksllskkkyeeavkWLqraldilekqelellssdlselrlsilrllakayleldteeslekaeklvell 111 +Y++g l+++++y+ a L++ + i++k +e + d+++lr+s+l la++ +l++ e a+++ ++l FUN_000449-T1 130 CYKVGNWLSASRRYSRA---LKQLILIGDKLPHECKE-DFEQLRVSCLLNLAACQGKLEQFEFV--AQNCTKVL 197 9****************...*********88888777.6***************9987777765..44544444 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.15 2.6e+02 4 22 .. 130 148 .. 127 149 .. 0.85 2 ? 3.4 0.0 0.053 90 20 39 .. 196 215 .. 195 218 .. 0.85 3 ? 9.0 0.0 0.00094 1.6 1 26 [. 211 236 .. 211 251 .. 0.93 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.15 TPR_11 4 yyeqGkyeeAieaYkkAlk 22 +y+ G++ A +Y++Alk FUN_000449-T1 130 CYKVGNWLSASRRYSRALK 148 688899999********98 PP == domain 2 score: 3.4 bits; conditional E-value: 0.053 TPR_11 20 AlkldPdnaeayynLGlayy 39 l+ P+n a+y +G+a+ FUN_000449-T1 196 VLAMVPSNLKALYRRGQAFV 215 577789************85 PP == domain 3 score: 9.0 bits; conditional E-value: 0.00094 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPd 26 G+a++ ++++++A +++kAl+ dP FUN_000449-T1 211 GQAFVHLNEFDKAKVDLEKALAMDPC 236 89**********************95 PP >> THOC7 Tho complex subunit 7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.6 9e-05 0.15 18 76 .. 140 199 .. 131 259 .. 0.79 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 9e-05 THOC7 18 erplkrllkrllklvksl.esseeelqalredllldlaafelsieklqllaeanerever 76 r++ r lk+l + + l + +e+ ++lr + ll laa++ +e +++a+ +++ ++ FUN_000449-T1 140 SRRYSRALKQLILIGDKLpHECKEDFEQLRVSCLLNLAACQGKLEQFEFVAQNCTKVLAM 199 688888888888866666766789*****************************9987765 PP >> FKBP_N_2 BDBT FKBP like N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 0.00018 0.31 52 89 .. 40 77 .. 4 99 .. 0.70 2 ? -1.7 0.0 2.8 4.7e+03 51 82 .. 221 255 .. 185 258 .. 0.58 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00018 FKBP_N_2 52 iesekvlviGsAlteiDryiEiliqmlklgEkalvtik 89 + ek++viG+ +e +E ++ ++ +E ++ FUN_000449-T1 40 LAIEKEIVIGEGDSEFSETLEKCLECMHTHEVCVIPCD 77 34689**************************8877554 PP == domain 2 score: -1.7 bits; conditional E-value: 2.8 FKBP_N_2 51 e...iesekvlviGsAlteiDryiEiliqmlklgE 82 + ++ ek+l + + + ++ l q+ +l+E FUN_000449-T1 221 DkakVDLEKALAMDPCNRAVQEQLRALKQKQSLHE 255 23334556666666655555555555555555555 PP >> Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.62 1.1e+03 11 27 .. 130 147 .. 129 150 .. 0.70 2 ? -2.0 0.0 3.6 6.2e+03 7 37 .. 176 206 .. 172 208 .. 0.73 3 ? 8.7 0.2 0.0016 2.7 10 42 .. 213 246 .. 204 255 .. 0.78 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.62 Fis1_TPR_C 11 hyklgeY.seArryvdal 27 +yk+g+ s +rry +al FUN_000449-T1 130 CYKVGNWlSASRRYSRAL 147 788888735567777665 PP == domain 2 score: -2.0 bits; conditional E-value: 3.6 Fis1_TPR_C 7 lAvGhyklgeYseArryvdalLeiePenrQa 37 lA + kl +++ + + +L++ P+n a FUN_000449-T1 176 LAACQGKLEQFEFVAQNCTKVLAMVPSNLKA 206 5566667777777778888899999999876 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0016 Fis1_TPR_C 10 GhyklgeYseArryvdalLeiePenrQaqe.Lke 42 + + l+e+++A+ ++ L+++P nr +qe L++ FUN_000449-T1 213 AFVHLNEFDKAKVDLEKALAMDPCNRAVQEqLRA 246 667799********************88752444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (273 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 898 (0.0351537); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2686.04 // Query: FUN_000450-T1 [L=732] Description: FUN_000450 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-25 89.2 14.8 5.3e-17 62.0 4.8 2.2 2 MFS_2 MFS/sugar transport protein 7.8e-17 61.7 21.3 2.3e-13 50.3 5.1 2.6 3 MFS_1 Major Facilitator Superfamily Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.0 4.8 4.2e-21 5.3e-17 3 198 .. 41 251 .. 39 272 .. 0.84 2 ! 32.9 2.3 2.8e-12 3.6e-08 214 371 .. 504 658 .. 467 707 .. 0.86 Alignments for each domain: == domain 1 score: 62.0 bits; conditional E-value: 4.2e-21 MFS_2 3 glgalaagllsaalatyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidrtr.....trwGrrrPwlllsaiilalsfillftppelsq 93 g+g + +++ +l + l+F +vlg+sa g++ l lv + + p+ ++++dr + ++ G+r+ w ll++++ a+++ l+f++ l + FUN_000450-T1 41 GMGHVLNDIARQLLFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVHipvvsKKFGKRKCWHLLGTVLEAVFVPLFFSAYYLIR 136 67777777777888888899*************************************7533222799************************99988 PP MFS_2 94 a.......alliwllalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLm 182 ++i++++l +ll +++e++++sl+pv++k++ e +l++ r f++l+g+l ++a + +++ s k ++++ f+++ a L+ FUN_000450-T1 137 NedgqterMMMIYFGILNVLLGFGGSLLEIAHLSLIPVIAKNQMEAVELSALRTAFTYLSGILTFVVAWVTFGLDSKSKISEDTSKDFMVLTATLV 232 899999***********************************************************************6666666666666666666 PP MFS_2 183 llgvilt...algtkervs 198 ++gv+l+ +gtke + FUN_000450-T1 233 AVGVLLSlifHMGTKEPIK 251 6666555000556666543 PP == domain 2 score: 32.9 bits; conditional E-value: 2.8e-12 MFS_2 214 leqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglvlall 308 ++ +++ + ++ l ++++ f+ + + ++ l ++ y lg +++ i++++l++ i+a+l++++ +++ +G+k ++++++l+ + +v+ ++ FUN_000450-T1 504 NKTIRSWLTDPRLYMVAIAFSCPNALQKHAYSYLPLFLIYRLGlSKQSIAYLPLITSISATLSSIFSKKFVGTMGNKLCFIIAATLVSSAGVMSFF 599 677889999999999999999999999999****************************************************************** PP MFS_2 309 l.qasnlllflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfslisklala 371 + ++s+ ++++ + ++ g+g+ ++ + s++++++ +++ +++g++fa++s++s l+ + FUN_000450-T1 600 MePGSSDAMIYPAAILLGLGFSSMYVNSISLATELIGENK-----KSSGFVFAFMSFTSYLISG 658 *88999******************************9998.....99**********9988765 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 2.8 6.7e-09 8.6e-05 4 172 .. 43 242 .. 40 297 .. 0.72 2 ! 50.3 5.1 1.8e-17 2.3e-13 171 341 .. 479 655 .. 465 661 .. 0.79 3 ? -3.8 0.3 0.5 6.4e+03 273 287 .. 690 704 .. 684 715 .. 0.49 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 6.7e-09 MFS_1 4 aaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfa....... 82 + +l+ ++r+ll+++ ++++ lgis+ g+l+ l+ a+++++ ++l+dr+ G+r+ + llg++l a++ + l+f+ FUN_000450-T1 43 GHVLNDIARQLLFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVhipvvskkfGKRKcWHLLGTVLEAVF-VPLFFSayylirn 137 678899999999999888999*********************************55555555555*****************.6666633444455 PP MFS_1 83 ...ss....lwlllvlrvlqGlgagalfpaaaaliadwfpk.eergralgllsagfglGaalGpllggllaslfg..........wravFlilail 160 ++ + ++ +l vl+G+g+++l a +li +++ e +l +a++ l+++l ++ ++++ fg F++l + FUN_000450-T1 138 edgQTermmMIYFGILNVLLGFGGSLLEIAHLSLIPVIAKNqMEAVELSALRTAFTYLSGILTFVV-AWVT--FGldskskisedTSKDFMVLTAT 230 543224442224778888**********************95566666677777888887777555.5555..33334666665544445555555 PP MFS_1 161 allaavlaalll 172 +++++vl+ l++ FUN_000450-T1 231 LVAVGVLLSLIF 242 555555444444 PP == domain 2 score: 50.3 bits; conditional E-value: 1.8e-17 MFS_1 171 llprpppeskrkkpaee..apapllp....awkallrdpvlwlllalllfglaffa....lltllply.qevlglsglllaglllglaallgaigr 255 +lp+++ +s+++ + +e ++ +++ l+dp+l +++++++ + +a +++lpl+ + +lgls ++++l+ ++++ + +++ FUN_000450-T1 479 YLPETKEKSEPFGKLDEnlPRS---DvankTIRSWLTDPRL---YMVAIAFSCPNAlqkhAYSYLPLFlIYRLGLS-KQSIAYLPLITSISATLSS 567 5555555555555555554222...2334778999999955...4444444455555678****************.8999999********999* PP MFS_1 256 lllgrlsdrlgrrrrlllallllllaalgllllsltesslwlllallllGfgfglvfplllalvsdlapk..eergtasglyntagsl 341 +++ +++ +g++ +++a+ l+ a+++ +++ + +s ++++ a +llG+gf+ +++++++l+++l+++ + +g+++++++++++l FUN_000450-T1 568 IFSKKFVGTMGNKLCFIIAATLVSSAGVMSFFMEPGSSDAMIYPAAILLGLGFSSMYVNSISLATELIGEnkKSSGFVFAFMSFTSYL 655 ************************************99****99************************65226666677777755554 PP == domain 3 score: -3.8 bits; conditional E-value: 0.5 MFS_1 273 lallllllaalglll 287 +a++l +l+a++++l FUN_000450-T1 690 VAIALSILGAVAVML 704 333333333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (732 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 888 (0.0347622); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7071.49 // Query: FUN_000451-T1 [L=183] Description: FUN_000451 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.092 12.8 0.0 0.12 12.4 0.0 1.1 1 DUF6338 Family of unknown function (DUF6338) 0.24 11.4 0.6 21 5.1 0.3 2.1 2 SieB Super-infection exclusion protein B Domain annotation for each model (and alignments): >> DUF6338 Family of unknown function (DUF6338) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 9.7e-06 0.12 53 123 .. 90 167 .. 72 174 .. 0.76 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 9.7e-06 DUF6338 53 lyllvlgllralgpall.ldpgallleaplwavllalllllavpallaalv.......salrrrrrrlavyssaptaWd 123 yl+ g+l + ++l+ +++g e ++ +l++ l+++a+++l +++v + +++r++++++y s++t Wd FUN_000451-T1 90 SYLIS-GPLVIIIQKLFpEQKGTECEECGRYLQLVFPLVAIALSILGGVAVlllhcigRFKEKREKEDRRYFSQQTIWD 167 36666.3333444555523334334478889999999999999999999999999999899*****************9 PP >> SieB Super-infection exclusion protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.3 0.0017 21 19 63 .. 65 109 .. 62 121 .. 0.85 2 ? 5.0 0.0 0.0017 22 30 71 .. 115 157 .. 110 162 .. 0.86 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0017 SieB 19 leklnldkfvteyglfiglvllisiayllsqliskllkevkerlk 63 e++ +++ ++ ++ +++++ +++yl+s + +++++ + ++k FUN_000451-T1 65 YEAIRIQAYIYRKTSGFVFAFMSFTSYLISGPLVIIIQKLFPEQK 109 578889999999999999999999*******99999998876655 PP == domain 2 score: 5.0 bits; conditional E-value: 0.0017 SieB 30 eyglfiglvl.lisiayllsqliskllkevkerlkkkreqkev 71 e+g ++ lv+ l++ia+ + + ll + + r+k+kre++ + FUN_000451-T1 115 ECGRYLQLVFpLVAIALSILGGVAVLLLHCIGRFKEKREKEDR 157 6677888888799**********************99998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (183 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 885 (0.0346447); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.54 # Mc/sec: 1360.02 // Query: FUN_000452-T1 [L=67] Description: FUN_000452 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-05 24.0 0.0 6.6e-05 23.0 0.0 1.6 2 TPR_1 Tetratricopeptide repeat 0.0014 19.1 0.0 0.0027 18.2 0.0 1.4 1 TPR_2 Tetratricopeptide repeat 0.0033 18.0 0.0 0.0057 17.2 0.0 1.4 1 TPR_8 Tetratricopeptide repeat 0.0045 17.5 0.0 0.0055 17.2 0.0 1.1 1 TPR_9 Tetratricopeptide repeat ------ inclusion threshold ------ 0.02 16.0 0.0 0.027 15.6 0.0 1.2 1 TPR_14 Tetratricopeptide repeat 0.022 15.6 0.0 0.024 15.4 0.0 1.1 1 TPR_19 Tetratricopeptide repeat 0.058 14.6 0.0 0.099 13.8 0.0 1.4 1 TPR_6 Tetratricopeptide repeat 0.061 14.3 0.0 0.078 13.9 0.0 1.2 1 TPR_16 Tetratricopeptide repeat 0.1 13.4 0.0 0.18 12.6 0.0 1.4 1 TPR_17 Tetratricopeptide repeat 0.14 12.5 0.0 0.14 12.5 0.0 1.1 1 HEAT_Nup120 Nucleoporin Nup120, HEAT repeats 0.23 12.5 0.0 0.25 12.4 0.0 1.2 1 U1snRNP70_N U1 small nuclear ribonucleoprotein of 70kDa MW N Domain annotation for each model (and alignments): >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 2.9e-08 6.6e-05 2 32 .. 24 54 .. 23 54 .. 0.93 2 ? -3.2 0.0 5.7 1.3e+04 24 28 .. 55 59 .. 55 62 .. 0.58 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 2.9e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALelnP 32 +al+++G+a+ +l+++d+A + ekA ++P FUN_000452-T1 24 NALFRRGQAFVHLNEFDKAKVDLEKAFPVDP 54 59************************87776 PP == domain 2 score: -3.2 bits; conditional E-value: 5.7 TPR_1 24 yekAL 28 +++A+ FUN_000452-T1 55 CNRAV 59 45555 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 1.2e-06 0.0027 3 27 .. 25 49 .. 23 51 .. 0.95 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.2e-06 TPR_2 3 alynlGlayyklgdyeeAleayekA 27 al+++G+a +l+++++A+ ++ekA FUN_000452-T1 25 ALFRRGQAFVHLNEFDKAKVDLEKA 49 8***********************9 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 2.5e-06 0.0057 2 28 .. 24 50 .. 23 54 .. 0.90 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 2.5e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekal 28 a++++G++ l+++++Ak +eka FUN_000452-T1 24 NALFRRGQAFVHLNEFDKAKVDLEKAF 50 689**********************96 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 2.4e-06 0.0055 21 60 .. 15 54 .. 12 64 .. 0.87 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 2.4e-06 TPR_9 21 llllaPddpeerrdrGllyaqlgcleaAladLeaylalap 60 +l++ P ++ rG++ ++l+ + +A dLe++ ++p FUN_000452-T1 15 VLAMLPSNLNALFRRGQAFVHLNEFDKAKVDLEKAFPVDP 54 58899999*************************9988888 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 1.2e-05 0.027 2 41 .. 24 63 .. 23 66 .. 0.93 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.2e-05 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlal 41 +a+ ++++a++ l+++d+A le+a dP +++++++l FUN_000452-T1 24 NALFRRGQAFVHLNEFDKAKVDLEKAFPVDPCNRAVQEQL 63 78999*****************************999877 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.0 1e-05 0.024 14 56 .. 12 54 .. 6 64 .. 0.83 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1e-05 TPR_19 14 LeqalaedPdnaearllLArallalgrldeAealLaalpaadp 56 ++la+ P n a+ + ++a ++l+++d+A+ L+++ + dp FUN_000452-T1 12 AGKVLAMLPSNLNALFRRGQAFVHLNEFDKAKVDLEKAFPVDP 54 5789***************************977777666665 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 4.3e-05 0.099 2 25 .. 25 48 .. 24 50 .. 0.94 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 4.3e-05 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 Al++ ++++ l+++d+Ak l++ FUN_000452-T1 25 ALFRRGQAFVHLNEFDKAKVDLEK 48 9******************99987 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 3.4e-05 0.078 22 50 .. 14 42 .. 7 54 .. 0.85 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 3.4e-05 TPR_16 22 aalrrnPeaaaAllglGlallrqgrlaeA 50 +l++ P++ Al+++G+a+ +++++++A FUN_000452-T1 14 KVLAMLPSNLNALFRRGQAFVHLNEFDKA 42 578888*********************99 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 7.7e-05 0.18 4 33 .. 14 43 .. 12 44 .. 0.94 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.7e-05 TPR_17 4 kaleldPnnadayynLArlllnnGqleeAl 33 k+l++ P n +a++ ++++ +++++++A+ FUN_000452-T1 14 KVLAMLPSNLNALFRRGQAFVHLNEFDKAK 43 78999**********************995 PP >> HEAT_Nup120 Nucleoporin Nup120, HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 6e-05 0.14 14 52 .. 11 49 .. 5 62 .. 0.92 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 6e-05 HEAT_Nup120 14 lalellrflpetpwstYvkGrllLalgefdeAaelFkka 52 a ++l +lp++ + + +G++++ l+efd+A+ ++ka FUN_000452-T1 11 SAGKVLAMLPSNLNALFRRGQAFVHLNEFDKAKVDLEKA 49 5778999*****************************998 PP >> U1snRNP70_N U1 small nuclear ribonucleoprotein of 70kDa MW N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00011 0.25 2 29 .. 18 45 .. 17 62 .. 0.85 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00011 U1snRNP70_N 2 kLPpnllkLFaprpPlrylppldkapee 29 LP+nl +LF+ + + +l+ dka+ + FUN_000452-T1 18 MLPSNLNALFRRGQAFVHLNEFDKAKVD 45 59********************999765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (67 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 335 (0.0131141); expected 510.9 (0.02) Passed bias filter: 318 (0.0124486); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.25u 0.35s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 699.52 // Query: FUN_000453-T1 [L=672] Description: FUN_000453 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-17 62.6 6.5 3.3e-17 62.6 6.5 2.0 2 MFS_2 MFS/sugar transport protein 5.6e-07 29.3 15.3 0.00015 21.3 3.2 3.1 3 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 7.5 6.8 5.6 4 7.7 0.5 2.6 2 8xMP Octameric membrane protein family (8xMP) Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.6 6.5 3.9e-21 3.3e-17 3 199 .. 37 248 .. 35 265 .. 0.86 2 ! 2.5 0.1 0.0069 58 77 125 .. 619 663 .. 603 672 .] 0.70 Alignments for each domain: == domain 1 score: 62.6 bits; conditional E-value: 3.9e-21 MFS_2 3 glgalaagllsaalatyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidrtr.....trwGrrrPwlllsaiilalsfillftppelsq 93 glg + +++ ++ + l+F +vlg+sa g++ l lv + + p+ ++++dr + ++ G+r+ w ll++++ a+++ l+ft++ l + FUN_000453-T1 37 GLGHVLNDITRQVFFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVHipvvsKKFGKRKCWHLLGTVLEAVFVPLFFTAHYLIR 132 56666667777777777788*************************************7533222799**************************999 PP MFS_2 94 a.......alliwllalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLm 182 ++i++++l +ll + t++e+ ++sl+pv++k++ e ++++ r f++l+g+l ++a + +++ s k ++++ f+++ a L+ FUN_000453-T1 133 NedgqterMMMIYFGILNVLLGFAGTLLEIVHLSLIPVIAKNQTEAVEMSVLRTAFTYLSGILTFVVAWITFGLDSKSKISEDTSKDFMVLTATLV 228 899999***********************************************************************7777777777777777777 PP MFS_2 183 llgvilta...lgtkervsl 199 ++gv+++ +gtke ++ FUN_000453-T1 229 AVGVLFSLifhVGTKEPINM 248 77777764111566666655 PP == domain 2 score: 2.5 bits; conditional E-value: 0.0069 MFS_2 77 ilalsfillftppelsqaalliwllalyillrvlytffevpyvslvpvl 125 + +++++ +f+ p+ ++ +++ +ill + ++ ++v ++sl+ +l FUN_000453-T1 619 VSSAGVMSFFMEPG----SSDSMIYPAAILLGLGFSSMYVNSISLATEL 663 44567777888888....6777777778888888888888888888776 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 3.2 1.7e-08 0.00015 3 177 .. 38 243 .. 36 279 .. 0.79 2 ! 9.3 0.9 7.8e-05 0.67 194 252 .. 558 627 .. 532 631 .. 0.63 3 ! 10.4 1.5 3.6e-05 0.31 272 327 .. 613 668 .. 609 672 .] 0.72 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 1.7e-08 MFS_1 3 laaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfass.... 84 l+ +l+ ++r++++++ ++++ lgis+ g+l+ l+ a+++++ ++l+dr+ G+r+ + llg++l a++ + l+f+++ FUN_000453-T1 38 LGHVLNDITRQVFFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVhipvvskkfGKRKcWHLLGTVLEAVF-VPLFFTAHylir 132 7889999999999999988999*********************************55555555555*****************.666664222333 PP MFS_1 85 ..........lwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfg..........wravFlilail 160 + ++ +l vl+G+++ +l + +li +++ + + +++l ++f+ + + ++ ++++ fg F++l + FUN_000453-T1 133 nedgqtermmMIYFGILNVLLGFAGTLLEIVHLSLIPVIAKNQTEAVEMSVLRTAFTYLSGILTFVVAWIT--FGldskskisedTSKDFMVLTAT 226 3444445543224778888***********************88888888888888888888888889998..55457877777655568888888 PP MFS_1 161 allaavlaalllprppp 177 +++++vl+ l++ + + FUN_000453-T1 227 LVAVGVLFSLIFHVGTK 243 88888887777765544 PP == domain 2 score: 9.3 bits; conditional E-value: 7.8e-05 MFS_1 194 p.......awkallrdpvlw.lllalllfglaffalltllply.qevlgls..glllaglllglaallga 252 p +++ l+dp+l+ + +a+ + + + +++lpl+ + +lgls ++ a++l++ a+++++ FUN_000453-T1 558 PrsdgadkTIRSWLTDPRLYmVAIAFSCPNSLQKYAYSYLPLFlIYRLGLSklCFTIAAILVSSAGVMSF 627 04444455688999999775566666666666666****************7733444444444444443 PP == domain 3 score: 10.4 bits; conditional E-value: 3.6e-05 MFS_1 272 llallllllaalgllllsltesslwlllallllGfgfglvfplllalvsdlapkee 327 ++a++l+ a+++ +++ + +s +++ a +llG+gf+ +++++++l+++l+++++ FUN_000453-T1 613 TIAAILVSSAGVMSFFMEPGSSDSMIYPAAILLGLGFSSMYVNSISLATELIGENK 668 34455555555555555555688888889999999999999999999999998654 PP >> 8xMP Octameric membrane protein family (8xMP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.5 0.00047 4 19 68 .. 185 240 .. 175 244 .. 0.75 2 ? 0.3 0.5 0.095 8.1e+02 30 69 .. 616 656 .. 604 663 .. 0.63 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.00047 8xMP 19 wkrntfFltlntalfaalglllsssese......pkellllalallGlllslaWfl 68 +++t++ + t ++a + + l+s+++ + +l +l+++G+l+sl+ + FUN_000453-T1 185 RTAFTYLSGILTFVVAWITFGLDSKSKIsedtskDFMVLTATLVAVGVLFSLIFHV 240 6788999999999999998888844444457766666788888888*****99765 PP == domain 2 score: 0.3 bits; conditional E-value: 0.095 8xMP 30 talfaalgllls.ssesepkellllalallGlllslaWflv 69 ++l++ +g++ ++ ++ +++ a +llGl +s +++ + FUN_000453-T1 616 AILVSSAGVMSFfMEPGSSDSMIYPAAILLGLGFSSMYVNS 656 33333343333333344445577788888899999988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (672 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1234 (0.0483069); expected 510.9 (0.02) Passed bias filter: 751 (0.0293991); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.43u 0.37s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 6385.67 // Query: FUN_000454-T1 [L=733] Description: FUN_000454 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-21 74.6 12.5 1.8e-15 56.9 4.6 2.1 2 MFS_2 MFS/sugar transport protein 7.7e-17 61.7 15.3 1.8e-12 47.3 2.5 2.6 2 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.17 13.0 1.6 0.37 11.8 0.4 1.9 2 IHABP4_N Intracellular hyaluronan-binding protein 4 N-term 9.9 6.8 9.1 36 5.0 3.5 3.1 3 Sec61_beta Sec61beta family Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.9 4.6 2.9e-19 1.8e-15 3 191 .. 37 237 .. 35 259 .. 0.88 2 ! 22.7 1.0 7e-09 4.5e-05 214 371 .. 505 659 .. 470 707 .. 0.88 Alignments for each domain: == domain 1 score: 56.9 bits; conditional E-value: 2.9e-19 MFS_2 3 glgalaagllsaalatyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidrtr.....trwGrrrPwlllsaiilalsfillftppelsq 93 glg + +++ +l + l+F +vlg+sa g++ l lv + + p+ ++++dr + ++ G+r+ w ll++++ a+++ l+f++ l FUN_000454-T1 37 GLGHVLNDITRQLLFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVHipvvsKKFGKRKCWHLLGTVLEAVFVPLFFSAYYLIG 132 66777777777777788899*************************************7533222799************************98766 PP MFS_2 94 a.......alliwllalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLm 182 ++i++++l +ll +++e++++sl+pv++k++ e +l++ r f++l+g+l ++a + +++ s + ++++ f+++ + L+ FUN_000454-T1 133 NedgqterMMMIYFGILNVLLGFGGSLLEIAHLSLIPVIAKNQMEAVELSALRTAFTYLSGILTFVVAWVTFGLDSKSNISEDTSKDFMVLTTTLV 228 679999***********************************************************************8888888888888888888 PP MFS_2 183 llgviltal 191 ++gv+l+ + FUN_000454-T1 229 AAGVFLSLV 237 888888743 PP == domain 2 score: 22.7 bits; conditional E-value: 7e-09 MFS_2 214 leqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglvlall 308 ++ +++ + ++ l ++++ f+ + + ++ l ++ + lg +++ i++++l++ i+a l+++l +++ iG+k ++++++l+ + +v+ ++ FUN_000454-T1 505 NKTIRSWLTDPRLYMVAIAFSCPNALQKHVYSYLPLFLIHRLGlSKKSIAYIPLITSISASLSSILSKKFVGTIGSKLCFIIAATLVSSAGVMSYF 600 56788888888999999999998888888888899999999999**************************************************** PP MFS_2 309 l.qasnlllflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfslisklala 371 ++ + ++++ + ++ g+g+ ++ + s+++ ++ +++ +++g++fa++s++s l+ + FUN_000454-T1 601 TePGCSEAMIYPAAILLGLGFSSMYVNSISLATKLIGENK-----KSSGFVFAFMSFTSYLISG 659 *7777889999999**********************9998.....99**********9988876 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 5.1 9.6e-08 0.00062 3 141 .. 38 200 .. 36 267 .. 0.76 2 ! 47.3 2.5 2.9e-16 1.8e-12 194 341 .. 500 656 .. 463 661 .. 0.76 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 9.6e-08 MFS_1 3 laaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfa...... 82 l+ +l+ ++r+ll+++ ++++ lgis+ g+l+ l+ a+++++ ++l+dr+ G+r+ + llg++l a++ + l+f+ FUN_000454-T1 38 LGHVLNDITRQLLFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVhipvvskkfGKRKcWHLLGTVLEAVF-VPLFFSayylig 132 7889999999999999988999*********************************55555555555*****************.666663344444 PP MFS_1 83 ...ss.....lwlllvlrvlqGlgagalfpaaaaliadwfpk.eergralgllsagfglGaalGpllg 141 + + ++ +l vl+G+g+++l a +li +++ e +l +a++ l+++l +++ FUN_000454-T1 133 nedGQtermmMIYFGILNVLLGFGGSLLEIAHLSLIPVIAKNqMEAVELSALRTAFTYLSGILTFVVA 200 4441144443224778888*********************9966666666888888888888776554 PP == domain 2 score: 47.3 bits; conditional E-value: 2.9e-16 MFS_1 194 p......awkallrdpvlwlllalllfglaffa....lltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallll 278 +++ l+dp+l +++++++ + +a ++++lpl+ + +lgls ++++++ ++++ ++++++l+ +++ +g++ +++a+ l+ FUN_000454-T1 500 RsdvankTIRSWLTDPRL---YMVAIAFSCPNAlqkhVYSYLPLFlIHRLGLS-KKSIAYIPLITSISASLSSILSKKFVGTIGSKLCFIIAATLV 591 122334678899999955...4444444455555678****************.8999999*******9999********999*998888888888 PP MFS_1 279 llaalgllllsltesslwlllallllGfgfglvfplllalvsdlapk..eergtasglyntagsl 341 a+++ +++ + s ++++ a +llG+gf+ +++++++l+++l+++ + +g+++++++++++l FUN_000454-T1 592 SSAGVMSYFTEPGCSEAMIYPAAILLGLGFSSMYVNSISLATKLIGEnkKSSGFVFAFMSFTSYL 656 888888888888889999999************************65225666666666655554 PP >> IHABP4_N Intracellular hyaluronan-binding protein 4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.41 2.6e+03 60 79 .. 283 302 .. 277 317 .. 0.81 2 ? 11.8 0.4 5.8e-05 0.37 58 114 .. 370 425 .. 346 432 .. 0.80 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.41 IHABP4_N 60 kaaarkgrkesqkerkedla 79 +++ +++rk+s+ rk+ + FUN_000454-T1 283 ATGIKAVRKDSRSSRKSSRV 302 5577899********98755 PP == domain 2 score: 11.8 bits; conditional E-value: 5.8e-05 IHABP4_N 58 ktkaaarkgrkesqkerkedlaskeqqpdkgeekevdrngerrtprrgeqqgqkegr 114 +++ ++++kes+ rk ++ + +++++k ++ n ++ p+r+e ++ + + FUN_000454-T1 370 TKANVLKGAKKESCPSRKMSIVTFRDDIQSSPKKSNT-NEQKALPKRKESPAKDDLQ 425 444456889**************99999999555555.5569*****9988877765 PP >> Sec61_beta Sec61beta family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 2.4 1.5e+04 7 16 .. 452 461 .. 452 461 .. 0.86 2 ? 3.9 0.0 0.013 82 1 11 [. 592 602 .. 592 603 .. 0.96 3 ? 5.0 3.5 0.0057 36 20 40 .. 689 709 .. 687 710 .. 0.92 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 2.4 Sec61_beta 7 rfyeedapgi 16 r+ ++ a++i FUN_000454-T1 452 RYSDDSASKI 461 8999999987 PP == domain 2 score: 3.9 bits; conditional E-value: 0.013 Sec61_beta 1 ssaGLlrfyee 11 ssaG +++++e FUN_000454-T1 592 SSAGVMSYFTE 602 9*********8 PP == domain 3 score: 5.0 bits; conditional E-value: 0.0057 Sec61_beta 20 PkvVlvlslafiasVilLhil 40 P+v ++ls++ +++V+lLh + FUN_000454-T1 689 PLVAIALSILGGVAVMLLHCI 709 9******************76 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (733 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 867 (0.0339401); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 7075.18 // Query: FUN_000454-T2 [L=656] Description: FUN_000454 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-20 72.7 8.2 1.5e-15 57.2 4.6 2.1 2 MFS_2 MFS/sugar transport protein 1.1e-15 57.9 12.3 5.8e-11 42.4 0.7 2.3 2 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.14 13.2 1.8 0.32 12.1 0.4 1.9 2 IHABP4_N Intracellular hyaluronan-binding protein 4 N-termin Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.2 4.6 1.8e-19 1.5e-15 3 191 .. 37 237 .. 35 259 .. 0.88 2 ! 17.1 0.1 2.6e-07 0.0023 214 343 .. 505 636 .. 470 641 .. 0.85 Alignments for each domain: == domain 1 score: 57.2 bits; conditional E-value: 1.8e-19 MFS_2 3 glgalaagllsaalatyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidrtr.....trwGrrrPwlllsaiilalsfillftppelsq 93 glg + +++ +l + l+F +vlg+sa g++ l lv + + p+ ++++dr + ++ G+r+ w ll++++ a+++ l+f++ l FUN_000454-T2 37 GLGHVLNDITRQLLFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVHipvvsKKFGKRKCWHLLGTVLEAVFVPLFFSAYYLIG 132 66777777777777788899*************************************7533222799************************98766 PP MFS_2 94 a.......alliwllalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLm 182 ++i++++l +ll +++e++++sl+pv++k++ e +l++ r f++l+g+l ++a + +++ s + ++++ f+++ + L+ FUN_000454-T2 133 NedgqterMMMIYFGILNVLLGFGGSLLEIAHLSLIPVIAKNQMEAVELSALRTAFTYLSGILTFVVAWVTFGLDSKSNISEDTSKDFMVLTTTLV 228 679999***********************************************************************8888888888888888888 PP MFS_2 183 llgviltal 191 ++gv+l+ + FUN_000454-T2 229 AAGVFLSLV 237 888888743 PP == domain 2 score: 17.1 bits; conditional E-value: 2.6e-07 MFS_2 214 leqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglvlall 308 ++ +++ + ++ l ++++ f+ + + ++ l ++ + lg +++ i++++l++ i+a l+++l +++ iG+k ++++++l+ + +v+ ++ FUN_000454-T2 505 NKTIRSWLTDPRLYMVAIAFSCPNALQKHVYSYLPLFLIHRLGlSKKSIAYIPLITSISASLSSILSKKFVGTIGSKLCFIIAATLVSSAGVMSYF 600 56788888888899999999998888888888889999999999**************************************************** PP MFS_2 309 l.qasnlllflvllviagfgvalaallpasmiadvv 343 ++ + ++++ + ++ g+g+ ++ + s+++ ++ FUN_000454-T2 601 TePGCSEAMIYPAAILLGLGFSSMYVNSISLATKLI 636 *66667788888888888888888877777777766 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 5.1 6e-08 0.00051 3 141 .. 38 200 .. 36 268 .. 0.76 2 ! 42.4 0.7 6.8e-15 5.8e-11 194 328 .. 500 641 .. 462 646 .. 0.79 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 6e-08 MFS_1 3 laaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfa...... 82 l+ +l+ ++r+ll+++ ++++ lgis+ g+l+ l+ a+++++ ++l+dr+ G+r+ + llg++l a++ + l+f+ FUN_000454-T2 38 LGHVLNDITRQLLFSFRLVFFMNVLGISAENSGWLALEKQLVHAAMAPVCAVLVDRVhipvvskkfGKRKcWHLLGTVLEAVF-VPLFFSayylig 132 7889999999999999988999*********************************55555555555*****************.666663344444 PP MFS_1 83 ...ss.....lwlllvlrvlqGlgagalfpaaaaliadwfpk.eergralgllsagfglGaalGpllg 141 + + ++ +l vl+G+g+++l a +li +++ e +l +a++ l+++l +++ FUN_000454-T2 133 nedGQtermmMIYFGILNVLLGFGGSLLEIAHLSLIPVIAKNqMEAVELSALRTAFTYLSGILTFVVA 200 4441144443224778888*********************9966666666888888888888776554 PP == domain 2 score: 42.4 bits; conditional E-value: 6.8e-15 MFS_1 194 p......awkallrdpvlwlllalllfglaffa....lltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallll 278 +++ l+dp+l +++++++ + +a ++++lpl+ + +lgls ++++++ ++++ ++++++l+ +++ +g++ +++a+ l+ FUN_000454-T2 500 RsdvankTIRSWLTDPRL---YMVAIAFSCPNAlqkhVYSYLPLFlIHRLGLS-KKSIAYIPLITSISASLSSILSKKFVGTIGSKLCFIIAATLV 591 122334678899999955...4444444455555678****************.8999999*******9999********999*998888888888 PP MFS_1 279 llaalgllllsltesslwlllallllGfgfglvfplllalvsdlapkeer 328 a+++ +++ + s ++++ a +llG+gf+ +++++++l+++l+++++ FUN_000454-T2 592 SSAGVMSYFTEPGCSEAMIYPAAILLGLGFSSMYVNSISLATKLIGENKV 641 888888888888889999999***********************988765 PP >> IHABP4_N Intracellular hyaluronan-binding protein 4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.27 2.3e+03 59 79 .. 282 302 .. 277 318 .. 0.81 2 ? 12.1 0.4 3.8e-05 0.32 58 114 .. 370 425 .. 346 432 .. 0.80 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.27 IHABP4_N 59 tkaaarkgrkesqkerkedla 79 t+++ +++rk+s+ rk+ + FUN_000454-T2 282 TATGIKAVRKDSRSSRKSSRV 302 45577899********98765 PP == domain 2 score: 12.1 bits; conditional E-value: 3.8e-05 IHABP4_N 58 ktkaaarkgrkesqkerkedlaskeqqpdkgeekevdrngerrtprrgeqqgqkegr 114 +++ ++++kes+ rk ++ + +++++k ++ n ++ p+r+e ++ + + FUN_000454-T2 370 TKANVLKGAKKESCPSRKMSIVTFRDDIQSSPKKSNT-NEQKALPKRKESPAKDDLQ 425 444456889**************99999999555555.5569*****9988877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (656 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 932 (0.0364846); expected 510.9 (0.02) Passed bias filter: 605 (0.0236837); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6411.96 // Query: FUN_000455-T1 [L=723] Description: FUN_000455 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-17 63.9 11.9 2e-10 40.3 4.7 2.2 2 MFS_2 MFS/sugar transport protein 1.3e-14 54.3 8.6 4.3e-13 49.4 2.1 2.4 2 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.011 16.6 1.5 0.036 14.9 1.1 2.2 1 Wzz Chain length determinant protein 0.099 13.3 2.7 0.23 12.1 0.3 2.6 2 ARL6IP6 Haemopoietic lineage transmembrane helix 0.24 11.8 2.8 2.6 8.4 0.0 2.3 2 DUF2637 Protein of unknown function (DUF2637) 0.34 10.2 4.8 0.96 8.7 1.5 2.1 2 DUF7937 Domain of unknown function (DUF7937) 0.55 9.9 3.1 0.9 9.2 0.5 2.0 2 DUF6350 Family of unknown function (DUF6350) 1.1 9.2 4.3 2.6 8.0 4.3 1.6 1 DUF2981 Protein of unknown function (DUF2981) 1.5 7.8 8.0 2.9 6.8 8.0 1.4 1 SpoIIE_N Stage II sporulation protein E N-terminal 1.5 9.8 9.1 42 5.1 0.1 3.0 2 EMC6_arch EMC6-arch 3.3 8.8 9.0 5.5 8.1 4.8 2.9 3 MerC MerC mercury resistance protein 9.1 6.7 7.5 1 9.8 0.9 2.6 3 DUF3754 Protein of unknown function (DUF3754) Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 0.7 4.6e-10 9.8e-07 100 202 .. 5 109 .. 1 127 [. 0.81 2 ! 40.3 4.7 9.5e-14 2e-10 208 369 .. 504 664 .. 480 717 .. 0.86 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 4.6e-10 MFS_2 100 llalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsg...tkeerkgylifaligaiLmllgviltalg 192 l++l ++l ++++++sl++v+++d+ e +++s+r fs+l+g+l ++a +++++ s+ +++ + +++++ + ++ +l+ ++ +lg FUN_000455-T1 5 LGILNVILGFGDGILDISHLSLIAVIARDQMEAVEMNSMRTSFSYLSGILTFVVAWVIFGLDSEsqlSESSSRDFMVLTGVLVAVGILSSLIFYLG 100 5666666777777899************************************************7776666777777777777778888889999* PP MFS_2 193 tkervslrkk 202 tke s ++ FUN_000455-T1 101 TKEPSSS-PP 109 **99765.33 PP == domain 2 score: 40.3 bits; conditional E-value: 9.5e-14 MFS_2 208 kealslleqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivg 302 +++++ ++ +++ + ++ l ++ + ++ +++ + ++ l ++ + l+ ++ i++++lvlti+a++++ + +++++iG k +++++++ai+ FUN_000455-T1 504 PRSTRGNKTVRRWLIDPRLYLVSIAYSCTWTLQIHAYSYLPLFLIHRLRfSKESIAYLPLVLTISATVSSSILKKIVQKIGDKLCIIFAAIFAIIA 599 566666788999999999****************************************************************************** PP MFS_2 303 lvlalllqasnl...llflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfsliskla 369 +v+ ++++a ++ ++++ +++ gf++ ++++ s++++++ ++ + +g++fav++li ++ FUN_000455-T1 600 GVMSYFMEAESWtskVMIYPTVILLGFAFSSMFVSSLSFATELIGKNT-----KTTGFVFAVMTLIASVT 664 *******5555511156666778999999999999*********9999.....77888888888887655 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 0.5 0.00059 1.2 90 188 .. 7 119 .. 3 160 .. 0.70 2 ! 49.4 2.1 2e-16 4.3e-13 195 343 .. 512 661 .. 454 666 .. 0.76 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.00059 MFS_1 90 vlrvlqGlgagalfpaaaaliadwfpk.eergralgllsagfglGaalGpllggllaslfg........wravFlilailallaav...laalllp 173 +l v++G+g g+l + +lia ++ + e ++++ ++++ l+++l +++ ++ l + r ++++++l +++++ + ++l FUN_000455-T1 7 ILNVILGFGDGILDISHLSLIAVIARDqMEAVEMNSMRTSFSYLSGILTFVVAWVIFGLDSesqlsessSRDFMVLTGVLVAVGILsslI--FYLG 100 67799*********************9778888889999999999999877777666444488887776333344444444444334214..7778 PP MFS_1 174 rpppeskrkkpaee....a 188 +++p s++++p ++ a FUN_000455-T1 101 TKEPSSSPPTPLRKlstlA 119 8888888887777743331 PP == domain 2 score: 49.4 bits; conditional E-value: 2e-16 MFS_1 195 awkallrdpvlw.lllalllfglaffa...lltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgl 285 + l dp+l+ + +a+ +++ ++ +++lpl+ + +l +s ++++l+ ++ + + +++ +l ++++++g + +++a++++++a+++ FUN_000455-T1 512 TVRRWLIDPRLYlVSIAYSCTW---TLqihAYSYLPLFlIHRLRFS-KESIAYLPLVLTISATVSSSILKKIVQKIGDKLCIIFAAIFAIIAGVMS 603 3455556665533333333333...33557****************.789999999999999999**************99999999999999999 PP MFS_1 286 lllslt..esslwlllallllGfgfglvfplllalvsdlapkeergtasglyntagslgg 343 +++ +s ++++ ++llGf+f+ +f+++l+++++l+ ++ + +g+++++++l + FUN_000455-T1 604 YFMEAEswTSKVMIYPTVILLGFAFSSMFVSSLSFATELI--GKNTKTTGFVFAVMTLIA 661 9998876567777777************************..666666777666665544 PP >> Wzz Chain length determinant protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 1.1 1.7e-05 0.036 17 50 .. 586 620 .. 573 641 .. 0.85 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 1.7e-05 Wzz 17 klIilvtllflllalaya.flatpkYtasaqilvp 50 kl i+++++f+++a++ + f+ + +t++++i++ FUN_000455-T1 586 KLCIIFAAIFAIIAGVMSyFMEAESWTSKVMIYPT 620 6778899999999999999*************985 PP >> ARL6IP6 Haemopoietic lineage transmembrane helix # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 0.83 1.8e+03 29 48 .. 48 67 .. 34 70 .. 0.85 2 ? 12.1 0.3 0.00011 0.23 24 62 .. 75 115 .. 67 123 .. 0.82 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.83 ARL6IP6 29 pllaGllvaiFsytivYlDs 48 + l G+l + ++ i lDs FUN_000455-T1 48 SYLSGILTFVVAWVIFGLDS 67 6899************9*99 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00011 ARL6IP6 24 rsklspllaGllva..iFsytivYlDsavPGvsPPsPlspr 62 +s+ +l+G+lva i s i Yl +P sPP+Pl + FUN_000455-T1 75 SSRDFMVLTGVLVAvgILSSLIFYLGTKEPSSSPPTPLRKL 115 566677899*99883358899****************9875 PP >> DUF2637 Protein of unknown function (DUF2637) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 4.5 0.0052 11 4 89 .. 589 672 .. 586 674 .. 0.82 2 ? 8.4 0.0 0.0012 2.6 78 139 .. 637 698 .. 623 707 .. 0.82 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0052 DUF2637 4 viavaivAviafalSF.aaLrelAqkaglsaslAwliPltvDglivaasllalaaslrrraalllrllawlltalslwfNvseatdv 89 +i++ai A+ia ++S+ + +k+++ + l+++ + + +++s l++a +l ++ ++ +++ +t++++ N+s +++ FUN_000455-T1 589 IIFAAIFAIIAGVMSYfMEAESWTSKVMI-YPTVILLGFAFSS--MFVSSLSFATELIGKNTKTTGFVFAVMTLIASVTNGSLLMTI 672 89*************98888899999997.3444555555555..555569*****************************9977766 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0012 DUF2637 78 slwfNvseatdvtldvvaaalslaanvafelvleaarrrierragleaakarpeLrllrwll 139 s + + ++ t++ v+a++ l a v +l ++++ + +++++ +++ ++Lrl+ l+ FUN_000455-T1 637 SFATELIGKNTKTTGFVFAVMTLIASVTNGSLLMTIQELFPEQRDKDWEECGDYLRLVFSLV 698 3333445559999*******************************************998777 PP >> DUF7937 Domain of unknown function (DUF7937) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.1 0.034 72 181 218 .. 52 91 .. 20 120 .. 0.58 2 ? 8.7 1.5 0.00045 0.96 204 334 .. 587 707 .. 506 712 .. 0.75 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.034 DUF7937 181 allvlavallavlgalr...gsaawrlvlvalGaavlvagv 218 +l +va++++++ + + ++r+ +v G++v+v + FUN_000455-T1 52 GILTFVVAWVIFGLDSEsqlSESSSRDFMVLTGVLVAVG-I 91 344444455444444444455555555555555555552.2 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00045 DUF7937 204 lvlvalGaavlvagvlvwalgagrsleafhgiaqntstvGfgllllpalaAlaaspalrrampasapaarwlgaarrallliavvavasalvrlld 299 l+ + ++ +++agv+ ++ a+++ ++++ + ++ll +++ + +l a++ + ++ g++ +++lia v +s l+++ + FUN_000455-T1 587 LCIIFAAIFAIIAGVMSYFMEAESWTSKVMIYP--------TVILLGFAFSSMFVSSLSFATELIGKNTKTTGFVFAVMTLIASVTNGSLLMTIQE 674 556666667777777777777777777777733........5666666666444445544555555788888888888999999999999999999 PP DUF7937 300 lvvavsldlpggrgvdlvlllvlglltavvAlvar 334 l+ ++ d + + l+lv++l+ ++vA+v + FUN_000455-T1 675 LFPEQ-RDKDWEEC-GDYLRLVFSLVNVGVAIVSM 707 99999.44444444.57789999999999999865 PP >> DUF6350 Family of unknown function (DUF6350) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.18 3.9e+02 77 123 .. 49 95 .. 23 136 .. 0.53 2 ? 9.2 0.5 0.00042 0.9 37 157 .. 551 712 .. 539 720 .. 0.60 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.18 DUF6350 77 vlaaalayalvaallallarsgavapsllqallgaalvaalgallga 123 l+++l+++++ ++ +l ++s+ ++s ++ + +++a+g+l + FUN_000455-T1 49 YLSGILTFVVAWVIFGLDSESQLSESSSRDFMVLTGVLVAVGILSSL 95 44455555555555555444444444444444444444444444422 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00042 DUF6350 37 ltlgggtvslvPLgltlllvll...aaragrraaradravlaavlaaalayalvaallallarsgavapsllqallgaalvaalgall........ 121 l++++ ++ ++PL lt+ + + + +++++++ + +++a+ +a++a+++++++++ s+++ +++ ++v +lg + FUN_000455-T1 551 LRFSKESIAYLPLVLTISATVSssiLKKIVQKIGD------KLCIIFAAIFAIIAGVMSYFMEA----ESWTSKVMIYPTVILLGFAFssmfvssl 636 55666678888999998887774444444554444......45889999999999999996444....5677777777777777777755555666 PP DUF6350 122 ..........................gavr................arllallpevlraalraaaaalavllavgall 157 ++ ++ + ++lr + ++ +++a++ +v +ll FUN_000455-T1 637 sfateligkntkttgfvfavmtliasV--TngsllmtiqelfpeqrDKDWEECGDYLRLVFSLVNVGVAIVSMVTVLL 712 666666666655555555554444430..1444444455555444455555555555555555555555555555444 PP >> DUF2981 Protein of unknown function (DUF2981) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 4.3 0.0012 2.6 182 280 .. 321 418 .. 242 427 .. 0.68 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0012 DUF2981 182 latvdsdlddldklkkllresdtkrgvdaanvsv.pkaataPelkete.veidslpatpekPakqaeddkdeslyddiPlvPhlgeteGeaeevsk 275 ++ d + dd + r s+ + + +++ vs k+ +P++k ++ v i+s +t++k ++ + + +++d+iP P ++t+ e++ +s+ FUN_000455-T1 321 VSFLDLYSDDES--NYTGRVSKETAPINQSAVSLeTKNDLLPDTKANSqVAINSELNTANKKNRPSRKRACVTFWDEIPSTPPKDDTN-ESQTLSN 413 333444433333..333344666666666666651556789****8863789************99*999************999996.9999999 PP DUF2981 276 eelPP 280 ee P FUN_000455-T1 414 EEEAP 418 98766 PP >> SpoIIE_N Stage II sporulation protein E N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 8.0 0.0013 2.9 101 230 .. 566 698 .. 531 713 .. 0.70 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0013 SpoIIE_N 101 illalllflllaklleklekkelkllpllvflssllvrllllllaeeltlyelllaaveavLsfvLtliFlqsiplltlkkkkkslkneEivcliI 196 ++ a++ +l+k+++k+ + kl ++ + ++++ ++ ++++ e + ++++ +L+f + +F+ s+++ t k++ + + +++ FUN_000455-T1 566 TISATVSSSILKKIVQKIGD---KLCIIFAAIFAIIAGVMSYFMEAESWTSKVMIYPTVILLGFAFSSMFVSSLSFATELIGKNTKTTGFVFAVMT 658 33333444444444444444...444445555556666677776666666777777888999****************99999999999999**** PP SpoIIE_N 197 llasvltGtvgwevyglsvehv......lsrYlvllfalv 230 l+asv G + +++++l e+ + Yl l+f+lv FUN_000455-T1 659 LIASVTNGSLLMTIQELFPEQRdkdweeCGDYLRLVFSLV 698 **************99977653222222556666666666 PP >> EMC6_arch EMC6-arch # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.02 42 6 48 .. 43 89 .. 39 104 .. 0.75 2 ? 4.3 5.8 0.036 77 9 62 .. 590 642 .. 582 670 .. 0.60 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.02 EMC6_arch 6 kvTalaallGiiagvlsalvag....aaaaasdtlallvllaailvq 48 +T ++ l Gi++ v++ +++g ++ ++s+ ++vl +++++ FUN_000455-T1 43 MRTSFSYLSGILTFVVAWVIFGldseSQLSESSSRDFMVLTGVLVAV 89 57999*******************99566666777777776666655 PP == domain 2 score: 4.3 bits; conditional E-value: 0.036 EMC6_arch 9 alaallGiiagvlsalvag.aaaaasdtlallvllaailvqklifpllkidveef 62 ++aa++ iiagv+s+++ + +++ + +++ll+ ++++ + + l++ +e+ FUN_000455-T1 590 IFAAIFAIIAGVMSYFMEAeSWTSKVMIYPTVILLG-FAFSSMFVSSLSF-ATEL 642 689**************9742222333333334433.3344344455555.3444 PP >> MerC MerC mercury resistance protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.1 0.66 1.4e+03 11 69 .. 51 112 .. 42 128 .. 0.58 2 ? 8.1 4.8 0.0026 5.5 17 101 .. 559 661 .. 556 667 .. 0.63 3 ? 0.7 0.0 0.53 1.1e+03 8 59 .. 655 705 .. 648 716 .. 0.63 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.66 MerC 11 ClihClalPlllallpalgllf.le..eelfhrlllilvlliallalllgyrrhrkllplvl 69 + i ++++ +++ l + ++l+ + + ++ +l++v +++ l ++lg++++ + p+ l FUN_000455-T1 51 SGILTFVVAWVIFGLDSESQLSeSSsrDFMVLTGVLVAVGILSSLIFYLGTKEPSSSPPTPL 112 55555554444444444333332221133455556666677777778888887777766655 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0026 MerC 17 a.lPlllallpalgllf.le..eelfhrlllilvlliallalllgy.rrhrkllplvlgllGlallllalllg..........gaiekl....... 90 a lPl+l+++++++ ++ + +++ +l +i+++++a++a +++y ++ +++ +v+ ++ll +a + + FUN_000455-T1 559 AyLPLVLTISATVSSSIlKKivQKIGDKLCIIFAAIFAIIAGVMSYfMEAESWTSKVMIYPTVILLGFAFSSMfvsslsfateL----Igkntktt 650 448999999999998874334456688889999999*********966666676666666666666555444455555333330....24444444 PP MerC 91 ltvlGsllliv 101 +v+++++li+ FUN_000455-T1 651 GFVFAVMTLIA 661 55555555554 PP == domain 3 score: 0.7 bits; conditional E-value: 0.53 MerC 8 SllClihClalPlllallpalgllf.le.eelfhrlllilvlliallalllgyr 59 ++++li ++ +ll ++++lf + ++ +++ + +l l+++l+ ++++ FUN_000455-T1 655 AVMTLIASVTNG---SLLMTIQELFpEQrDKDWEECGDYLRLVFSLVNVGVAIV 705 555555555533...333445555555658889999999999999988887765 PP >> DUF3754 Protein of unknown function (DUF3754) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 0.59 1.3e+03 59 105 .. 41 92 .. 20 105 .. 0.64 2 ? 9.8 0.9 0.00049 1 51 104 .. 577 631 .. 576 641 .. 0.85 3 ? -2.4 0.1 2.7 5.8e+03 70 99 .. 655 699 .. 646 711 .. 0.50 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.59 DUF3754 59 dklklgvaaivalitvilkll.....kaekvkeklseliavliavlalggfa 105 ++ + + +++t++++ + ++++++e+ s ++vl+ vl+++g++ FUN_000455-T1 41 NSMRTSFSYLSGILTFVVAWVifgldSESQLSESSSRDFMVLTGVLVAVGIL 92 4556666777788888888778888855555555555555555555555544 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00049 DUF3754 51 kkvsvrlkdklklgvaaivalitvilkll.kaekvkeklseliavliavlalggf 104 kk++ ++ dkl + +aai+a+i+ ++++ +ae++++k+++ +v+++ +a++++ FUN_000455-T1 577 KKIVQKIGDKLCIIFAAIFAIIAGVMSYFmEAESWTSKVMIYPTVILLGFAFSSM 631 6899999*******************986699***99999988888877776655 PP == domain 3 score: -2.4 bits; conditional E-value: 2.7 DUF3754 70 alitvilkll...............kaekvkeklseliavliavl 99 a++t+i+++ ++++++e l +v+++v FUN_000455-T1 655 AVMTLIASVTngsllmtiqelfpeqRDKDWEECGDYLRLVFSLVN 699 333333333344444444444466666666666556666666444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (723 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1246 (0.0487767); expected 510.9 (0.02) Passed bias filter: 586 (0.0229399); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 6922.55 // Query: FUN_000457-T1 [L=73] Description: FUN_000457 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-08 33.0 0.1 8.1e-08 32.8 0.1 1.1 1 QRICH1 QRICH1 domain ------ inclusion threshold ------ 0.026 15.1 0.3 0.044 14.3 0.1 1.5 2 DUF3330 Domain of unknown function (DUF3330) Domain annotation for each model (and alignments): >> QRICH1 QRICH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.8 0.1 6.3e-12 8.1e-08 46 93 .. 1 48 [. 1 52 [. 0.92 Alignments for each domain: == domain 1 score: 32.8 bits; conditional E-value: 6.3e-12 QRICH1 46 lsaeeLnyaLslfvkevrrpngekYapdsiyylclgiQqyLfengrid 93 +s e+L + +++fv evr+++ ++Y +iy +++++Q yL+ + r + FUN_000457-T1 1 MSDEDLDFLFARFVAEVRKKDRQEYPGKTIYEMICSLQCYLRFQRRRE 48 5789*************************************9887754 PP >> DUF3330 Domain of unknown function (DUF3330) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 0.39 5e+03 44 54 .. 11 21 .. 9 29 .. 0.62 2 ? 14.3 0.1 3.5e-06 0.044 34 54 .. 31 51 .. 24 67 .. 0.69 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.39 DUF3330 44 qrfearakava 54 rf a + ++ FUN_000457-T1 11 ARFVAEVRKKD 21 67877765443 PP == domain 2 score: 14.3 bits; conditional E-value: 3.5e-06 DUF3330 34 vehfcGlecyqrfearakava 54 e c l+cy rf+ r +++ FUN_000457-T1 31 YEMICSLQCYLRFQRRRESNS 51 6899**********8865443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (73 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 621 (0.02431); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 748.24 // Query: FUN_000458-T1 [L=103] Description: FUN_000458 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.025 14.9 0.0 0.032 14.6 0.0 1.1 1 Sigma70_ECF ECF sigma factor 0.049 13.8 0.0 0.068 13.3 0.0 1.2 1 HTH_33 Winged helix-turn helix 0.12 13.1 0.0 0.17 12.6 0.0 1.1 1 Clr5 Clr5 domain 0.14 12.5 0.0 0.17 12.2 0.0 1.1 1 DUF7626 Domain of unknown function (DUF7626) Domain annotation for each model (and alignments): >> Sigma70_ECF ECF sigma factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 5e-06 0.032 137 182 .. 49 103 .] 42 103 .] 0.77 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 5e-06 Sigma70_ECF 137 speqarlvelrvfeGlsveEiAeklg......vskrtver...nwalaRawlere 182 +++ l+ +++G++++EiA l +s rtv+r +++l Ra++++e FUN_000458-T1 49 GVNRDNLIRSYFLQGFTNAEIAGFLAlhhgiiLSVRTVKRifkRLRLTRAKCNNE 103 55666788899***********988633333369****97555899999999875 PP >> HTH_33 Winged helix-turn helix # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 1.1e-05 0.068 7 37 .. 66 96 .. 62 99 .. 0.90 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.1e-05 HTH_33 7 larlaqlieerfgvsysvsgvyrlLhrlGfs 37 a++a +++ g+ +sv++v r+++rl ++ FUN_000458-T1 66 NAEIAGFLALHHGIILSVRTVKRIFKRLRLT 96 588999999*******************987 PP >> Clr5 Clr5 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 2.6e-05 0.17 9 49 .. 52 92 .. 50 95 .. 0.95 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 2.6e-05 Clr5 9 ketIrrLYieenktLkevmeiMeeeygFkaskrqykrrfkk 49 +++++r Y ++ t +e++ +++ ++g s r kr fk+ FUN_000458-T1 52 RDNLIRSYFLQGFTNAEIAGFLALHHGIILSVRTVKRIFKR 92 788999999*****************************996 PP >> DUF7626 Domain of unknown function (DUF7626) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 2.7e-05 0.17 7 54 .. 54 101 .. 51 102 .. 0.88 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 2.7e-05 DUF7626 7 elivdmKqagysdkdIaekLvkegrvrYdpKTIgtRylRirkalqeee 54 li + +g+++ +Ia L+ ++ + + +T+ + R+r + ++++ FUN_000458-T1 54 NLIRSYFLQGFTNAEIAGFLALHHGIILSVRTVKRIFKRLRLTRAKCN 101 555555579********************************9999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 573 (0.022431); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1040.36 // Query: FUN_000459-T1 [L=472] Description: FUN_000459 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-09 35.8 14.9 1.3e-08 34.7 14.5 1.5 1 MFS_1 Major Facilitator Superfamily 1e-05 24.8 17.8 1.9e-05 23.9 17.8 1.4 1 MFS_2 MFS/sugar transport protein ------ inclusion threshold ------ 0.035 14.9 4.1 0.21 12.4 0.3 2.6 2 Wzz Chain length determinant protein 0.09 13.3 1.2 7.5 7.1 0.4 2.9 3 OCIA Ovarian carcinoma immunoreactive antigen (OCIA) 0.17 12.8 2.2 2.3 9.1 0.2 2.7 2 SCIMP SCIMP protein Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.7 14.5 2.5e-12 1.3e-08 195 341 .. 250 401 .. 216 405 .. 0.71 Alignments for each domain: == domain 1 score: 34.7 bits; conditional E-value: 2.5e-12 MFS_1 195 awkallrdpvlw.lllalllfglaffa...lltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgl 285 + l dp+l+ + +a+ ++++ + ++++lpl+ +l +s ++++l+ ++ + + + + l+ ++++++g +++a++++++a+++ FUN_000459-T1 250 TVRRWLIDPRLYlVSIAYSCAWM---LqihVYSYLPLFlLYRLRFS-KESIAYLPLIMTISATVYAKLSKKIVQKIGGMLCFIFAAIFAFAAGVMS 341 44556666766444444444444...3446****************.6777777777777777779999999999999777777666666666666 PP MFS_1 286 lllslt..esslwlllallllGfgfglvfplllalvsdlapk..eergtasglyntagsl 341 +++ +s ++++ ++llGf+f+ +f+++l+++++l++k + +g++++++++++s+ FUN_000459-T1 342 YFMEAEswTSEVMIYPTVVLLGFAFSSMFVSSLSFATELIGKntKTTGFVFAIMTLFSSI 401 6665555667777777************************55335555666666655554 PP >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 17.8 3.8e-09 1.9e-05 216 372 .. 250 405 .. 232 456 .. 0.86 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 3.8e-09 MFS_2 216 qlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglvlalllq 310 +++ + ++ l ++ + ++ a++ + ++ l ++ y l+ ++ i++++l++ti+a++ l +++++iG +++++++a++ +v+ ++++ FUN_000459-T1 250 TVRRWLIDPRLYLVSIAYSCAWMLQIHVYSYLPLFLLYRLRfSKESIAYLPLIMTISATVYAKLSKKIVQKIGGMLCFIFAAIFAFAAGVMSYFME 345 67788888899999999******************************************************************************5 PP MFS_2 311 asnl...llflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfslisklalal 372 a ++ ++++ +v+ gf++ ++++ s++++++ ++ + +g++fa+++l+s ++ + FUN_000459-T1 346 AESWtseVMIYPTVVLLGFAFSSMFVSSLSFATELIGKNT-----KTTGFVFAIMTLFSSITNGS 405 55551115667778999999999**************999.....89999*******99998774 PP >> Wzz Chain length determinant protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.3 0.035 1.8e+02 8 39 .. 285 316 .. 283 319 .. 0.87 2 ? 12.4 0.3 4.2e-05 0.21 18 50 .. 325 358 .. 322 379 .. 0.90 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.035 Wzz 8 LlkvLwkrkklIilvtllflllalayaflatp 39 Ll +L+ +k I+ ++l++++ a +ya l+++ FUN_000459-T1 285 LLYRLRFSKESIAYLPLIMTISATVYAKLSKK 316 66678888889****************99886 PP == domain 2 score: 12.4 bits; conditional E-value: 4.2e-05 Wzz 18 lIilvtllflllalaya.flatpkYtasaqilvp 50 l ++++++f+++a++ + f+ + +t++++i++ FUN_000459-T1 325 LCFIFAAIFAFAAGVMSyFMEAESWTSEVMIYPT 358 678999***********9*************985 PP >> OCIA Ovarian carcinoma immunoreactive antigen (OCIA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.025 1.3e+02 6 31 .. 225 246 .. 220 257 .. 0.82 2 ? 7.1 0.4 0.0015 7.5 26 75 .. 299 345 .. 291 353 .. 0.84 3 ? -1.4 0.0 0.69 3.5e+03 22 45 .. 428 450 .. 418 460 .. 0.70 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.025 OCIA 6 seeerrvlreCnresFfqrslPlsvv 31 + + v++ Cn+es slPls+ FUN_000459-T1 225 MSDRKPVVKSCNTES----SLPLSTG 246 567888********8....8888875 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0015 OCIA 26 lPlsvvsglvtyllvkkgvLsassrfgslPkvavagilgyliGklsYqkk 75 lPl +++ ++ y+ ++k+++ +++g + ++a+i+++ +G +sY+ + FUN_000459-T1 299 LPLIMTISATVYAKLSKKIV---QKIGGMLCFIFAAIFAFAAGVMSYFME 345 78888888888888888776...6899********************865 PP == domain 3 score: -1.4 bits; conditional E-value: 0.69 OCIA 22 fqrslPlsvvsglvtyllvkkgvL 45 + l +svv ++++ + v + +L FUN_000459-T1 428 Y-MRLAFSVVNVAIAIVSVVNVLL 450 4.4489999999999998877655 PP >> SCIMP SCIMP protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.1 0.047 2.4e+02 43 92 .. 108 157 .. 96 191 .. 0.79 2 ? 9.1 0.2 0.00045 2.3 11 33 .. 435 457 .. 427 464 .. 0.86 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.047 SCIMP 43 iakplkqkerdeekmyenvlnqspvqlPplPPrgllsledsspqetksqp 92 i l+ ++++ e + + +++P+ PP++ + + ++ p+e+++ + FUN_000459-T1 108 INSELNTANQKNSLSREKACVAFWDEIPSTPPKDDTNERQTLPNEEEAPI 157 5556666666666677777888899**********999999999887644 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00045 SCIMP 11 ilavaiivvsvvlglilycvcrr 33 ++ vai +vsvv l+lyc+ r FUN_000459-T1 435 VVNVAIAIVSVVNVLLLYCMNRF 457 6789***************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (472 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1244 (0.0486984); expected 510.9 (0.02) Passed bias filter: 621 (0.02431); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4640.54 // Query: FUN_000460-T1 [L=814] Description: FUN_000460 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-22 78.0 17.3 8.2e-15 54.7 5.2 2.2 2 MFS_2 MFS/sugar transport protein 1.4e-12 47.7 4.0 1.4e-12 47.7 4.0 2.7 3 MFS_1 Major Facilitator Superfamily 0.0091 15.4 13.1 0.031 13.7 6.1 3.1 3 Sugar_tr Sugar (and other) transporter ------ inclusion threshold ------ 0.067 13.5 16.4 0.049 14.0 2.2 3.2 3 DUF6773 Family of unknown function (DUF6773) 0.84 10.3 8.8 7.8 7.2 0.4 3.8 3 DUF1299 Protein of unknown function (DUF1299) Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.7 5.2 1.6e-18 8.2e-15 26 193 .. 2 181 .. 1 208 [. 0.91 2 ! 29.0 4.2 1.1e-10 5.4e-07 210 369 .. 588 744 .. 570 797 .. 0.86 Alignments for each domain: == domain 1 score: 54.7 bits; conditional E-value: 1.6e-18 MFS_2 26 dvlglsaaavglvllvarlvDvitdpivGaiidrtrt.....rwGrrrPwlllsaiilalsfillftppelsqa.......alliwllalyillrv 109 +vlglsa g+++l +v ++ p+ ++++dr + ++G+ + w ll+ai++a+++ llf++ l ++ ++i++++l ++l+ FUN_000460-T1 2 NVLGLSAENSGWLVLQKQMVHTVMAPLCAILVDRVHIppvsrKLGKKKTWHLLGAILQAVFVPLLFAANYLIRSedgkteqMMMIYFGVLNVILAF 97 79********************************864333339************************************9999************* PP MFS_2 110 lytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLmllgviltalgt 193 ++++++sl++ l+kd+ e +l++ r+ fs+l+++l ++a + ++ s+ + +++ f+++ aiL+++g+++ ++++ FUN_000460-T1 98 GDIILDISHLSLISMLSKDQMEAVELSALRSAFSYLSSILTFVVAWVTFGQDSESQISEDSSKDFMILTAILVTVGFLFAVIFQ 181 ******************************************************999999999999999999999999988765 PP == domain 2 score: 29.0 bits; conditional E-value: 1.1e-10 MFS_2 210 alslleqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglv 304 + ++ + +++ + ++ l i+ + ++ ++ + ++ l ++ y l+ ++ i++++l++ i+a++++++ +l+ +iG+k +++g++++ + +v FUN_000460-T1 588 SHRAKKTMRSWLIEPRLYIVSFAYSCPLALQTQAYSYLPLLLIYRLRfSKESIAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAGV 683 556667888899999999999999999999999999************************************************************ PP MFS_2 305 lalll.qasnlllflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfsliskla 369 + +++ ++ + ++++ +++ gfg+ ++ + s++++++ +++ +g++f+++ lis ++ FUN_000460-T1 684 MSYFMePEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIGENK-----ETSGFVFGFMNLISYVV 744 *****777788888999999999999999999999999999888.....55566666666665555 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 3.5 6.5e-05 0.33 27 187 .. 4 195 .. 1 234 [. 0.72 2 ! 47.7 4.0 2.8e-16 1.4e-12 190 341 .. 590 743 .. 549 749 .. 0.79 3 ? -2.2 0.5 0.4 2.1e+03 211 224 .. 777 790 .. 767 804 .. 0.42 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 6.5e-05 MFS_1 27 lgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfass.............lw.lllvlrvlqGlg 98 lg+s+ g+l+ + ++++l ++l+dr+ G+++ + llg +l a++ + llfa++ + ++ vl v++++g FUN_000460-T1 4 LGLSAENSGWLVLQKQMVHTVMAPLCAILVDRVhippvsrklGKKKtWHLLGAILQAVF-VPLLFAANylirsedgkteqmMMiYFGVLNVILAFG 98 788999999999999999999999999999977777777777****999**********.4444544434444444544442225888888999** PP MFS_1 99 agalfpaaaaliadwfpk.eergralgllsagfglGaalGpllggllaslfg..........wrav..Flilailallaavlaalllprpppeskr 181 +l + +li+ ++++ e +l sa++ l+++l +++ + g + F+il ++++ +++l+a+++ + +e++ FUN_000460-T1 99 DIILDISHLSLISMLSKDqMEAVELSALRSAFSYLSSILTFVVAWVTF---GqdsesqisedS--SkdFMILTAILVTVGFLFAVIFQVGVKEPSS 189 999999999999999999667777778888888888888866654444...334465555442..1557777777777777778888666666666 PP MFS_1 182 kkpaee 187 ++ + FUN_000460-T1 190 SSRMPL 195 655444 PP == domain 2 score: 47.7 bits; conditional E-value: 2.8e-16 MFS_1 190 apllpawkallrdpvlwlllalllf..glaffalltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaa 282 + +++ +++ l p+l +++ ++++ ++ ++ +++lpl+ + +l +s ++++l+ ++++ + ++++++ +l+ ++g++ ++++++++ a+ FUN_000460-T1 590 RAKKT-MRSWLIEPRL-YIVSFAYScpLALQTQAYSYLPLLlIYRLRFS-KESIAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAG 682 33333.6666667766.4444444421334444****************.788888888888888888*************888888888888888 PP MFS_1 283 lgllllsltesslwlllallllGfgfglvfplllalvsdla..pkeergtasglyntagsl 341 ++ +++ + s ++++ ++llGfgf+ + +++l+++++l+ ke +g+++g++n+++++ FUN_000460-T1 683 VMSYFMEPEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIgeNKETSGFVFGFMNLISYV 743 8888888889*******************************66569999*******88875 PP == domain 3 score: -2.2 bits; conditional E-value: 0.4 MFS_1 211 lllfglaffalltl 224 l++f +++f+ + FUN_000460-T1 777 LVAFVFSTFGAFLV 790 11111111111111 PP >> Sugar_tr Sugar (and other) transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.2 0.037 1.9e+02 309 359 .. 40 92 .. 13 101 .. 0.70 2 ! 3.1 0.0 0.0095 48 140 184 .. 163 207 .. 154 213 .. 0.81 3 ! 13.7 6.1 6e-06 0.031 239 437 .. 588 790 .. 555 793 .. 0.73 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.037 Sugar_tr 309 flvdrfGRRkl.lllGaagmaicfvvlgivalllvske.ksasivaivfillf 359 +++ ++G++k+ +llGa+ +a++ +l + +l++s++ k ++++i f +l FUN_000460-T1 40 PVSRKLGKKKTwHLLGAILQAVFVPLLFAANYLIRSEDgKTEQMMMIYFGVLN 92 67888998654389999999999988886677777777888888888887664 PP == domain 2 score: 3.1 bits; conditional E-value: 0.0095 Sugar_tr 140 vslyqlaitfGillaaiiglglkktsnsdgWrillglqlvpalll 184 + l+ +t+G+l+a i+ +g+k+ s+s+++++ ++++ a l+ FUN_000460-T1 163 MILTAILVTVGFLFAVIFQVGVKEPSSSSRMPLRKLSTFAAANLM 207 56778899**************99999888888777777766655 PP == domain 3 score: 13.7 bits; conditional E-value: 6e-06 Sugar_tr 239 kaswkelfssktvrqrlligvvlqifqqltGinaifyYsttifeklglsds..llvtiivgvvnfvatfiaiflvdrfGRRkllllGaagmaicfv 332 ++ k+ ++s+ + rl i+ ++ a y++ ++ l +s++ ++ +i+++ +++++++ lv+++G + ++++Ga++ + + FUN_000460-T1 588 SHRAKKTMRSWLIEPRLYIVSFAYSCPLALQTQAYSYLPLLLIYRLRFSKEsiAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAG- 682 66677777777777777777777777777777888888888899999999888899999999999999999999999999999999976543333. PP Sugar_tr 333 vlgivalllvskeksasivaivfillfiaffalgwgpvpwvivsElfpqsvRskalalataanwlanflisllfpiitesig..........gayv 418 v++ ++++ + s+ +v + ill + f ++ ++++ ++El ++ ++++ + ++n ++ ++++ lf ii++ g+y FUN_000460-T1 683 VMS---YFMEPEF-SKVMVYPTVILLGFGFSSMLVNSLS--FATELIGENKETSGFVFG-FMNLISYVVVGPLFLIIQKFFPeqrgtdceecGGYL 771 333...4444442.4566777777777777777777777..556999999888888776.568999999999999999999889999999999999 PP Sugar_tr 419 flvfagllvlfiifvfffv 437 lvf ++ +f +f f v FUN_000460-T1 772 RLVFSLVAFVFSTFGAFLV 790 9999999999999988877 PP >> DUF6773 Family of unknown function (DUF6773) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.3 0.0055 28 84 139 .. 49 104 .. 41 128 .. 0.72 2 ? 3.2 1.3 0.02 1e+02 89 140 .. 133 184 .. 124 192 .. 0.84 3 ? 14.0 2.2 9.5e-06 0.049 14 154 .. 662 802 .. 659 812 .. 0.65 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0055 DUF6773 84 skknliiglvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfllv 139 ++ +l+++++ ++++ l+f+++ i+ +d+++++ + + + v+ v++++ ++l + FUN_000460-T1 49 KTWHLLGAILQAVFVPLLFAANYLIRSEDGKTEQMMMIYFGVLNVILAFGDIILDI 104 445688999999******************88888887777777777665444433 PP == domain 2 score: 3.2 bits; conditional E-value: 0.02 DUF6773 89 iiglvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfllvv 140 ++++++ +v + fg s + ++++k+++ +++ v f+++++f ++v FUN_000460-T1 133 LSSILTFVVAWVTFGQDSESQISEDSSKDFMILTAILVTVGFLFAVIFQVGV 184 6788888888999999999999999889999999999999999999998876 PP == domain 3 score: 14.0 bits; conditional E-value: 9.5e-06 DUF6773 14 knKIyseayilviiilllSilvksfvldasleqyltEliilivaglYysvRsvtlGdevelhdrkskkslskknliiglvlglvlalffgirsail 109 KI+s + ++ +i ++S v s++++ +++++++ ++++++ + s+ +l el +++++s+ +++ + +v lf i++++ FUN_000460-T1 662 VEKIGSKLCFIFGAIFVCSAGVMSYFMEPEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIGENKETSGFVFGFMNLISYVVVGPLFLIIQKFFP 757 67*********************************9877776666666655555553356666666666666666666666666666777777777 PP DUF6773 110 ygdkykkeaigyfllvflvsfiiylpfllvvlvilyslakkkskk 154 + ++ e+ g l +++ ++ + + ++lv+l + + + + k FUN_000460-T1 758 EQRGTDCEECGGYLRLVFSLVAFVFSTFGAFLVLLLYCMDRFQGK 802 777766666555444444444444444444455444444444443 PP >> DUF1299 Protein of unknown function (DUF1299) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.027 1.4e+02 17 37 .. 303 323 .. 298 333 .. 0.86 2 ? 2.7 0.5 0.036 1.9e+02 17 30 .. 429 442 .. 426 457 .. 0.85 3 ? 7.2 0.4 0.0015 7.8 16 36 .. 460 480 .. 455 484 .. 0.90 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.027 DUF1299 17 SDdEdNgTAPtEKESqpkKee 37 SDd +T + KE p K FUN_000460-T1 303 SDDTSDDTSHVRKETAPTKVS 323 9****************9965 PP == domain 2 score: 2.7 bits; conditional E-value: 0.036 DUF1299 17 SDdEdNgTAPtEKE 30 SDdE N+T + K+ FUN_000460-T1 429 SDDESNNTSCVGKD 442 9*******988775 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0015 DUF1299 16 LSDdEdNgTAPtEKESqpkKe 36 LS E Ng tEKE +p ++ FUN_000460-T1 460 LSETEANGANATEKENRPSRR 480 9***************99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (814 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1402 (0.0548835); expected 510.9 (0.02) Passed bias filter: 655 (0.025641); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.40 # Mc/sec: 8162.23 // Query: FUN_000460-T2 [L=907] Description: FUN_000460 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-20 71.4 18.6 3.4e-11 42.8 1.3 3.2 3 MFS_2 MFS/sugar transport protein 1.5e-12 47.6 3.7 1.5e-12 47.6 3.7 3.4 4 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.018 14.4 13.7 0.037 13.4 6.0 3.2 3 Sugar_tr Sugar (and other) transporter 0.16 12.1 0.2 0.29 11.3 0.2 1.3 1 YrbL-PhoP_reg PhoP regulatory network protein YrbL 0.21 11.9 18.7 0.057 13.7 2.2 3.7 4 DUF6773 Family of unknown function (DUF6773) 1.3 9.7 8.8 8.8 7.0 0.4 3.7 3 DUF1299 Protein of unknown function (DUF1299) Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.8 1.3 7.9e-15 3.4e-11 2 144 .. 35 189 .. 34 201 .. 0.89 2 ! 8.8 0.3 0.00017 0.71 135 193 .. 216 274 .. 203 301 .. 0.84 3 ! 28.7 4.2 1.5e-10 6.5e-07 210 368 .. 681 836 .. 663 890 .. 0.86 Alignments for each domain: == domain 1 score: 42.8 bits; conditional E-value: 7.9e-15 MFS_2 2 yglgalaagllsaalatyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidrtrt.....rwGrrrPwlllsaiilalsfillftppels 92 +g+g + +l+ +l + l+F +vlglsa g+++l +v ++ p+ ++++dr + ++G+ + w ll+ai++a+++ llf++ l FUN_000460-T2 35 FGVGHILNDLVVQLLFSFRLVFFMNVLGLSAENSGWLVLQKQMVHTVMAPLCAILVDRVHIppvsrKLGKKKTWHLLGAILQAVFVPLLFAANYLI 130 677777777777777777888*************************************864333339***************************** PP MFS_2 93 qa.......alliwllalyillrvlytffevpyvslvpvltkdydeRtkltsvreffst 144 ++ ++i++++l ++l+ ++++++sl++ l+kd+ e +l++ r+ + FUN_000460-T2 131 RSedgkteqMMMIYFGVLNVILAFGDIILDISHLSLISMLSKDQMEAVELSALRFEHEI 189 *******9999****************************************99986655 PP == domain 2 score: 8.8 bits; conditional E-value: 0.00017 MFS_2 135 ltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLmllgviltalgt 193 ++++r+ fs+l+++l ++a + ++ s+ + +++ f+++ aiL+++g+++ ++++ FUN_000460-T2 216 IFRFRSAFSYLSSILTFVVAWVTFGQDSESQISEDSSKDFMILTAILVTVGFLFAVIFQ 274 7899*************************999999999999999999999999988765 PP == domain 3 score: 28.7 bits; conditional E-value: 1.5e-10 MFS_2 210 alslleqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglv 304 + ++ + +++ + ++ l i+ + ++ ++ + ++ l ++ y l+ ++ i++++l++ i+a++++++ +l+ +iG+k +++g++++ + +v FUN_000460-T2 681 SHRAKKTMRSWLIEPRLYIVSFAYSCPLALQTQAYSYLPLLLIYRLRfSKESIAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAGV 776 5566677888999999999999999999999999999*********************************************************** PP MFS_2 305 lalll.qasnlllflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfsliskl 368 + +++ ++ + ++++ +++ gfg+ ++ + s++++++ +++ +g++f+++ lis + FUN_000460-T2 777 MSYFMePEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIGENK-----ETSGFVFGFMNLISYV 836 *****777788888999999999999999999999999999888.....5556666666666555 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 1.0 1.9e-05 0.083 217 292 .. 45 137 .. 22 176 .. 0.56 2 ? -0.9 0.4 0.2 8.4e+02 65 170 .. 256 271 .. 215 305 .. 0.53 3 ! 47.6 3.7 3.4e-16 1.5e-12 190 341 .. 683 836 .. 643 842 .. 0.79 4 ? -2.5 0.6 0.62 2.7e+03 211 224 .. 870 883 .. 861 896 .. 0.41 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 1.9e-05 MFS_1 217 affalltllply.qevlglsglllaglllglaallgaigrlllgrlsdr.........lgrrrrlllallllllaalgllllslt........e 292 ++++l+++ ++ ++vlgls + +g+l+ +++ ++++l++ l+dr lg+++++ l++++l ++++ ll++++ + FUN_000460-T2 45 VVQLLFSFRLVFfMNVLGLS-AENSGWLVLQKQMVHTVMAPLCAILVDRvhippvsrkLGKKKTWHLLGAILQAVFVPLLFAANYlirsedgkT 137 33333333333336666666.4555555555555555555555555555555555555666666666666666666666666665555555542 PP == domain 2 score: -0.9 bits; conditional E-value: 0.2 MFS_1 65 lllglllfalglllllfasslwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfgwravFlilail 160 + il ++ FUN_000460-T2 256 M------------------------------------------------------------------------------------------ILTAI 261 1..........................................................................................11111 PP MFS_1 161 allaavlaal 170 ++ +++l+a+ FUN_000460-T2 262 LVTVGFLFAV 271 1111111222 PP == domain 3 score: 47.6 bits; conditional E-value: 3.4e-16 MFS_1 190 apllpawkallrdpvlwlllalllf..glaffalltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaa 282 + +++ +++ l p+l +++ ++++ ++ ++ +++lpl+ + +l +s ++++l+ ++++ + ++++++ +l+ ++g++ ++++++++ a+ FUN_000460-T2 683 RAKKT-MRSWLIEPRL-YIVSFAYScpLALQTQAYSYLPLLlIYRLRFS-KESIAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAG 775 33333.6666667766.4444444421334444****************.788888888888888888*************888888888888888 PP MFS_1 283 lgllllsltesslwlllallllGfgfglvfplllalvsdla..pkeergtasglyntagsl 341 ++ +++ + s ++++ ++llGfgf+ + +++l+++++l+ ke +g+++g++n+++++ FUN_000460-T2 776 VMSYFMEPEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIgeNKETSGFVFGFMNLISYV 836 8888888889*******************************66569999*******88875 PP == domain 4 score: -2.5 bits; conditional E-value: 0.62 MFS_1 211 lllfglaffalltl 224 l++f +++f+ + FUN_000460-T2 870 LVAFVFSTFGAFLV 883 11111111111111 PP >> Sugar_tr Sugar (and other) transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.2 0.045 1.9e+02 309 359 .. 97 149 .. 57 159 .. 0.71 2 ? 2.9 0.0 0.013 55 140 184 .. 256 300 .. 247 306 .. 0.81 3 ? 13.4 6.0 8.6e-06 0.037 239 437 .. 681 883 .. 648 886 .. 0.73 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.045 Sugar_tr 309 flvdrfGRRkl.lllGaagmaicfvvlgivalllvske.ksasivaivfillf 359 +++ ++G++k+ +llGa+ +a++ +l + +l++s++ k ++++i f +l FUN_000460-T2 97 PVSRKLGKKKTwHLLGAILQAVFVPLLFAANYLIRSEDgKTEQMMMIYFGVLN 149 67889998754389999999999988886677777777888888888887664 PP == domain 2 score: 2.9 bits; conditional E-value: 0.013 Sugar_tr 140 vslyqlaitfGillaaiiglglkktsnsdgWrillglqlvpalll 184 + l+ +t+G+l+a i+ +g+k+ s+s+++++ ++++ a l+ FUN_000460-T2 256 MILTAILVTVGFLFAVIFQVGVKEPSSSSRMPLRKLSTFAAANLM 300 56778899**************99999888888777777766655 PP == domain 3 score: 13.4 bits; conditional E-value: 8.6e-06 Sugar_tr 239 kaswkelfssktvrqrlligvvlqifqqltGinaifyYsttifeklglsds..llvtiivgvvnfvatfiaiflvdrfGRRkllllGaagmaicfv 332 ++ k+ ++s+ + rl i+ ++ a y++ ++ l +s++ ++ +i+++ +++++++ lv+++G + ++++Ga++ + + FUN_000460-T2 681 SHRAKKTMRSWLIEPRLYIVSFAYSCPLALQTQAYSYLPLLLIYRLRFSKEsiAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAG- 775 66677777777677777777777777777777888888888889999999888889999999999999999999999999999999876543333. PP Sugar_tr 333 vlgivalllvskeksasivaivfillfiaffalgwgpvpwvivsElfpqsvRskalalataanwlanflisllfpiitesig..........gayv 418 v++ ++++ + s+ +v + ill + f ++ ++++ ++El ++ ++++ + ++n ++ ++++ lf ii++ g+y FUN_000460-T2 776 VMS---YFMEPEF-SKVMVYPTVILLGFGFSSMLVNSLS--FATELIGENKETSGFVFG-FMNLISYVVVGPLFLIIQKFFPeqrgtdceecGGYL 864 332...4444442.4566777777777777777777777..556999999888888776.568999999999999999999889999999999999 PP Sugar_tr 419 flvfagllvlfiifvfffv 437 lvf ++ +f +f f v FUN_000460-T2 865 RLVFSLVAFVFSTFGAFLV 883 9999999999999988876 PP >> YrbL-PhoP_reg PhoP regulatory network protein YrbL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.2 6.9e-05 0.29 96 145 .. 166 214 .. 160 218 .. 0.87 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6.9e-05 YrbL-PhoP_reg 96 leelvkkdeldkelkrkLdefkeylldnhivindlsakNivlkrnsegee 145 l ++++kd++++++ ++L +f +++ldn i+++++ + N++++ +++g++ FUN_000460-T2 166 LISMLSKDQMEAVELSAL-RFEHEILDNVIITIEITTDNVMMQADDKGDV 214 567789999999999999.59**********************9999874 PP >> DUF6773 Family of unknown function (DUF6773) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.4 0.0079 34 84 138 .. 106 160 .. 98 184 .. 0.72 2 ? 2.7 0.1 0.033 1.4e+02 92 143 .. 189 238 .. 167 255 .. 0.76 3 ? 2.7 1.5 0.033 1.4e+02 89 140 .. 226 277 .. 218 284 .. 0.84 4 ? 13.7 2.2 1.3e-05 0.057 14 154 .. 755 895 .. 752 905 .. 0.65 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.0079 DUF6773 84 skknliiglvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfll 138 ++ +l+++++ ++++ l+f+++ i+ +d+++++ + + + v+ v++++ ++l FUN_000460-T2 106 KTWHLLGAILQAVFVPLLFAANYLIRSEDGKTEQMMMIYFGVLNVILAFGDIILD 160 445688999999******************8888888777787777766544443 PP == domain 2 score: 2.7 bits; conditional E-value: 0.033 DUF6773 92 lvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfllvvlvi 143 ++ +++++ +++ ++++ +d++ +++f ++s++++++ ++v+ v+ FUN_000460-T2 189 ILDNVIITIEITTDNVMMQADDK--GDVFIFRFRSAFSYLSSILTFVVAWVT 238 5566899999*****99999995..777777788888888888888777654 PP == domain 3 score: 2.7 bits; conditional E-value: 0.033 DUF6773 89 iiglvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfllvv 140 ++++++ +v + fg s + ++++k+++ +++ v f+++++f ++v FUN_000460-T2 226 LSSILTFVVAWVTFGQDSESQISEDSSKDFMILTAILVTVGFLFAVIFQVGV 277 6788888888999999999999999889999999999999999999998876 PP == domain 4 score: 13.7 bits; conditional E-value: 1.3e-05 DUF6773 14 knKIyseayilviiilllSilvksfvldasleqyltEliilivaglYysvRsvtlGdevelhdrkskkslskknliiglvlglvlalffgirsail 109 KI+s + ++ +i ++S v s++++ +++++++ ++++++ + s+ +l el +++++s+ +++ + +v lf i++++ FUN_000460-T2 755 VEKIGSKLCFIFGAIFVCSAGVMSYFMEPEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIGENKETSGFVFGFMNLISYVVVGPLFLIIQKFFP 850 67*********************************9877776666666655555553356666666666666666666666666666777777777 PP DUF6773 110 ygdkykkeaigyfllvflvsfiiylpfllvvlvilyslakkkskk 154 + ++ e+ g l +++ ++ + + ++lv+l + + + + k FUN_000460-T2 851 EQRGTDCEECGGYLRLVFSLVAFVFSTFGAFLVLLLYCMDRFQGK 895 777766666555444444444444444444455444444444443 PP >> DUF1299 Protein of unknown function (DUF1299) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.1 0.036 1.6e+02 17 37 .. 396 416 .. 391 426 .. 0.86 2 ? 2.6 0.5 0.049 2.1e+02 17 30 .. 522 535 .. 519 550 .. 0.85 3 ? 7.0 0.4 0.0021 8.8 16 36 .. 553 573 .. 548 577 .. 0.90 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.036 DUF1299 17 SDdEdNgTAPtEKESqpkKee 37 SDd +T + KE p K FUN_000460-T2 396 SDDTSDDTSHVRKETAPTKVS 416 9****************9965 PP == domain 2 score: 2.6 bits; conditional E-value: 0.049 DUF1299 17 SDdEdNgTAPtEKE 30 SDdE N+T + K+ FUN_000460-T2 522 SDDESNNTSCVGKD 535 9*******988775 PP == domain 3 score: 7.0 bits; conditional E-value: 0.0021 DUF1299 16 LSDdEdNgTAPtEKESqpkKe 36 LS E Ng tEKE +p ++ FUN_000460-T2 553 LSETEANGANATEKENRPSRR 573 9***************99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (907 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1087 (0.0425524); expected 510.9 (0.02) Passed bias filter: 497 (0.0194559); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.38u 0.41s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 8718.42 // Query: FUN_000460-T3 [L=622] Description: FUN_000460 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-13 48.6 3.7 7.5e-13 48.6 3.7 1.7 2 MFS_1 Major Facilitator Superfamily 9.4e-07 28.2 6.4 1.5e-06 27.6 6.4 1.3 1 MFS_2 MFS/sugar transport protein ------ inclusion threshold ------ 0.011 15.2 6.1 0.018 14.4 6.1 1.3 1 Sugar_tr Sugar (and other) transporter 0.018 15.4 2.2 0.031 14.6 2.2 1.3 1 DUF6773 Family of unknown function (DUF6773) 0.56 11.3 2.8 0.72 10.9 0.4 2.1 2 IHABP4_N Intracellular hyaluronan-binding protein 4 N-termin 6.8 7.4 7.6 13 6.5 7.6 1.4 1 Rhomboid Rhomboid domain Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.6 3.7 1.8e-16 7.5e-13 190 341 .. 398 551 .. 356 557 .. 0.79 2 ? -1.7 0.5 0.34 1.4e+03 211 224 .. 585 598 .. 575 613 .. 0.43 Alignments for each domain: == domain 1 score: 48.6 bits; conditional E-value: 1.8e-16 MFS_1 190 apllpawkallrdpvlwlllalllf..glaffalltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaa 282 + +++ +++ l p+l +++ ++++ ++ ++ +++lpl+ + +l +s ++++l+ ++++ + ++++++ +l+ ++g++ ++++++++ a+ FUN_000460-T3 398 RAKKT-MRSWLIEPRL-YIVSFAYScpLALQTQAYSYLPLLlIYRLRFS-KESIAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAG 490 33333.6666677766.4444444421334444****************.788888888888888888*************888888888888888 PP MFS_1 283 lgllllsltesslwlllallllGfgfglvfplllalvsdla..pkeergtasglyntagsl 341 ++ +++ + s ++++ ++llGfgf+ + +++l+++++l+ ke +g+++g++n+++++ FUN_000460-T3 491 VMSYFMEPEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIgeNKETSGFVFGFMNLISYV 551 8888888889*******************************66569999*******88875 PP == domain 2 score: -1.7 bits; conditional E-value: 0.34 MFS_1 211 lllfglaffalltl 224 l++f +++f+ + FUN_000460-T3 585 LVAFVFSTFGAFLV 598 11111111111111 PP >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.6 6.4 3.5e-10 1.5e-06 210 369 .. 396 552 .. 378 606 .. 0.86 Alignments for each domain: == domain 1 score: 27.6 bits; conditional E-value: 3.5e-10 MFS_2 210 alslleqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglv 304 + ++ + +++ + ++ l i+ + ++ ++ + ++ l ++ y l+ ++ i++++l++ i+a++++++ +l+ +iG+k +++g++++ + +v FUN_000460-T3 396 SHRAKKTMRSWLIEPRLYIVSFAYSCPLALQTQAYSYLPLLLIYRLRfSKESIAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSAGV 491 55666788899999999999999999999999999************************************************************* PP MFS_2 305 lalll.qasnlllflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfsliskla 369 + +++ ++ + ++++ +++ gfg+ ++ + s++++++ +++ +g++f+++ lis ++ FUN_000460-T3 492 MSYFMePEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIGENK-----ETSGFVFGFMNLISYVV 552 *****777788889999999999999999999999999999988.....55666666666666555 PP >> Sugar_tr Sugar (and other) transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 6.1 4.3e-06 0.018 238 437 .. 394 598 .. 363 601 .. 0.74 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 4.3e-06 Sugar_tr 238 e.kaswkelfssktvrqrlligvvlqifqqltGinaifyYsttifeklglsds..llvtiivgvvnfvatfiaiflvdrfGRRkllllGaagmaic 330 + ++ k+ ++s+ + rl i+ ++ a y++ ++ l +s++ ++ +i+++ +++++++ lv+++G + ++++Ga++ + + FUN_000460-T3 394 SrSHRAKKTMRSWLIEPRLYIVSFAYSCPLALQTQAYSYLPLLLIYRLRFSKEsiAYLPLIMSISATMSSIFSKKLVEKIGSKLCFIFGAIFVCSA 489 346677777777777777777777777777777788888888899999999998889999999999999999999999999999999997654333 PP Sugar_tr 331 fvvlgivalllvskeksasivaivfillfiaffalgwgpvpwvivsElfpqsvRskalalataanwlanflisllfpiitesig..........ga 416 v++ ++++ + s+ +v + ill + f ++ ++++ ++El ++ ++++ + ++n ++ ++++ lf ii++ g+ FUN_000460-T3 490 G-VMS---YFMEPEF-SKVMVYPTVILLGFGFSSMLVNSLS--FATELIGENKETSGFVFG-FMNLISYVVVGPLFLIIQKFFPeqrgtdceecGG 577 3.333...4444442.4566777777777777777777777..556999999888888776.5699999999999999999998899999999999 PP Sugar_tr 417 yvflvfagllvlfiifvfffv 437 y lvf ++ +f +f f v FUN_000460-T3 578 YLRLVFSLVAFVFSTFGAFLV 598 999999999999999988877 PP >> DUF6773 Family of unknown function (DUF6773) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 2.2 7.3e-06 0.031 14 154 .. 470 610 .. 467 620 .. 0.65 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 7.3e-06 DUF6773 14 knKIyseayilviiilllSilvksfvldasleqyltEliilivaglYysvRsvtlGdevelhdrkskkslskknliiglvlglvlalffgirsail 109 KI+s + ++ +i ++S v s++++ +++++++ ++++++ + s+ +l el +++++s+ +++ + +v lf i++++ FUN_000460-T3 470 VEKIGSKLCFIFGAIFVCSAGVMSYFMEPEFSKVMVYPTVILLGFGFSSMLVNSLSFATELIGENKETSGFVFGFMNLISYVVVGPLFLIIQKFFP 565 67*********************************9877776666666655555553356666666666666666666666666666777777777 PP DUF6773 110 ygdkykkeaigyfllvflvsfiiylpfllvvlvilyslakkkskk 154 + ++ e+ g l +++ ++ + + ++lv+l + + + + k FUN_000460-T3 566 EQRGTDCEECGGYLRLVFSLVAFVFSTFGAFLVLLLYCMDRFQGK 610 777766666555444444444444444444555444444444443 PP >> IHABP4_N Intracellular hyaluronan-binding protein 4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.4 0.00017 0.72 14 110 .. 108 210 .. 106 231 .. 0.72 2 ? -0.2 0.1 0.45 1.9e+03 86 107 .. 268 291 .. 235 322 .. 0.61 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00017 IHABP4_N 14 dqllDDesDPf.dvLreaenkkekqkkkkerekaakgreagprggktkaaarkgrkesqkerkedlaskeqqpdkgeekevdrng......errtp 102 d+ DD sD+ +v +e + k +++ e ++ + +++ ++++ + rkes +k+ s e + + ++ d n e+ +p FUN_000460-T3 108 DLYSDDTSDDTsHVRKETAPTKVSALSVSAVETENVLLSETNSQHVSNSGLNTERKESFHAKKKSRISFEDKIQCR-LEKCDTNEgrtllkEKEPP 202 6778****99616666677789999999999****9967777777778899********99998888765555444.5555555546667666666 PP IHABP4_N 103 rrgeqqgq 110 + + q+++ FUN_000460-T3 203 KVNHQSSS 210 65555444 PP == domain 2 score: -0.2 bits; conditional E-value: 0.45 IHABP4_N 86 dkgeekevdrng...errtprrgeq 107 ++ ++ ++ n+ e r++rr+ FUN_000460-T3 268 LSE-TEANGANAtekENRPSRRRAR 291 222.222222224555556665543 PP >> Rhomboid Rhomboid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 7.6 0.0029 13 28 119 .. 463 563 .. 453 604 .. 0.85 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0029 Rhomboid 28 lvfGselerrlGsvrflllyllsgllgsllsllfsaass..........plvGaSgaifgllgallvlvprnrkllkslivalllllliillnlvl 113 +f ++l +++Gs+ ++++ ++++ ++++s++++++ s + +G+S++++ l++ + l+ +n++ ++++ + l+ +++++ ++ FUN_000460-T3 463 SIFSKKLVEKIGSKLCFIFGAIFVCSAGVMSYFMEPEFSkvmvyptvilLGFGFSSMLVNSLSFATELIGENKETSGFVFGF-MNLISYVVVGPLF 557 5799999****************************************99999************999999999999988888.7777777777777 PP Rhomboid 114 gllpsn 119 ++++++ FUN_000460-T3 558 LIIQKF 563 777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (622 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1203 (0.0470934); expected 510.9 (0.02) Passed bias filter: 564 (0.0220787); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.38u 0.35s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 6201.07 // Query: FUN_000461-T1 [L=826] Description: FUN_000461 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-15 57.4 11.5 9.7e-15 54.5 3.6 2.6 3 MFS_2 MFS/sugar transport protein 0.00015 21.3 7.3 0.02 14.3 0.0 3.0 3 MFS_1 Major Facilitator Superfamily Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.5 3.6 7.6e-19 9.7e-15 11 199 .. 42 245 .. 32 265 .. 0.84 2 ! 7.5 0.1 0.00014 1.8 223 292 .. 664 734 .. 646 751 .. 0.87 3 ? -2.1 0.1 0.11 1.4e+03 227 254 .. 783 810 .. 780 821 .. 0.62 Alignments for each domain: == domain 1 score: 54.5 bits; conditional E-value: 7.6e-19 MFS_2 11 llsaalatyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidrtrt.....rwGrrrPwlllsaiilalsfillftppelsqa....... 94 l +++ + l+F +vlglsa g+++l l+D ++ p+ + ++ r + ++G+ + w ll++++ ++++ l f+++ l ++ FUN_000461-T1 42 LCIQLFTSFRLVFFMNVLGLSAENSGWLVLQKELMDTVMAPVCAMLVNRVHIplvsrKYGKIKTWHLLGTVLHTVFVPLSFAAHYLIRSedgkteq 137 444556667778*************************************864333339************************************99 PP MFS_2 95 alliwllalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsg...tkeerkgylifaligaiLmllgvi 187 ++i++++l ++ + + ++++++ l++ ++kd+ e +l+++r+ fs+l+ +l ++a ++++ s+ + + k ++++++i ++ +l+ + FUN_000461-T1 138 MMMIYFGILNVISSFGDSILDISHLCLISAIAKDQMEAVELSAIRSVFSYLSDILTFVVAWVILGQDSEsqiSEDSSKDFMVLTAILVAVGVLTSL 233 99****************************************************************999555555566666666666666666667 PP MFS_2 188 ltalgtkervsl 199 + lgtke s FUN_000461-T1 234 IYHLGTKEPSSC 245 777888887665 PP == domain 2 score: 7.5 bits; conditional E-value: 0.00014 MFS_2 223 nrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkknty 292 ++ l i+ l++ +++ ++ ++ l ++ y l+ ++ i++++l++ i+a ++++l + +++iG+k ++ FUN_000461-T1 664 DPCLHIVSLTYTCQWVLEMLAFSYLPLLLIYRLRlSQGSIAYLPLIMSISASVSSILSKKVVQKIGNKVMV 734 55667788888999999999999999*****************************************9876 PP == domain 3 score: -2.1 bits; conditional E-value: 0.11 MFS_2 227 lilllvfllaalamgvlnalllYymryv 254 ++++ ++ +a+ ++g lllYy++ + FUN_000461-T1 783 RLVFSLGAVAFSTFGAFLVLLLYYINRF 810 5566666666666666666666666654 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.6 4.4e-05 0.56 217 311 .. 43 157 .. 31 193 .. 0.70 2 ! 14.3 0.0 1.6e-06 0.02 197 271 .. 659 734 .. 611 740 .. 0.69 3 ? -1.6 0.1 0.11 1.4e+03 131 145 .. 787 801 .. 779 818 .. 0.46 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 4.4e-05 MFS_1 217 affalltllply.qevlgls...........glllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgllllslt......... 291 ++++++++ ++ ++vlgls l+ +++++ a+l++ r+ + +s+++g+ +++ l++ +l ++++ l ++++ FUN_000461-T1 43 CIQLFTSFRLVFfMNVLGLSaensgwlvlqkELMDTVMAPVCAMLVN---RVHIPLVSRKYGKIKTWHLLGTVLHTVFVPLSFAAHYlirsedgkt 135 45555555555559999999999999999987677776666666666...99999999*****999999999999999999999999888888874 PP MFS_1 292 esslwlll..allllGfgfglv 311 e ++++++ + ++ +fg +++ FUN_000461-T1 136 EQMMMIYFgiLNVISSFGDSIL 157 3333333354555566677776 PP == domain 2 score: 14.3 bits; conditional E-value: 1.6e-06 MFS_1 197 kallrdpvlw....lllalllfglaffa....lltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrl 271 ++ w +l ++ l+ ++ + +++lpl+ + +l ls ++++l+ ++++ ++++++l+ ++++++g++ + FUN_000461-T1 659 RD-------WlfdpCLHIVSLTYTCQWVlemlAFSYLPLLlIYRLRLS-QGSIAYLPLIMSISASVSSILSKKVVQKIGNKVMV 734 22.......33344444444443444444777*******999999999.678888899999999999************98765 PP == domain 3 score: -1.6 bits; conditional E-value: 0.11 MFS_1 131 glGaalGpllgglla 145 +lGa+ + +g++l+ FUN_000461-T1 787 SLGAVAFSTFGAFLV 801 222222222222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (826 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1236 (0.0483852); expected 510.9 (0.02) Passed bias filter: 696 (0.027246); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.38u 0.41s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 7929.87 // Query: FUN_000462-T1 [L=921] Description: FUN_000462 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-22 79.5 15.9 3.5e-16 59.3 4.6 2.2 2 MFS_2 MFS/sugar transport protein 1.5e-11 44.3 2.8 1.5e-11 44.3 2.8 3.0 3 MFS_1 Major Facilitator Superfamily 0.001 19.4 2.7 0.001 19.4 2.7 3.2 3 DUF6773 Family of unknown function (DUF6773) Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.3 4.6 4.1e-20 3.5e-16 26 199 .. 2 188 .. 1 208 [. 0.91 2 ! 26.0 3.5 5.1e-10 4.4e-06 215 377 .. 703 862 .. 682 908 .. 0.76 Alignments for each domain: == domain 1 score: 59.3 bits; conditional E-value: 4.1e-20 MFS_2 26 dvlglsaaavglvllvarlvDvitdpivGaiidrtrt.....rwGrrrPwlllsaiilalsfillftppelsqa.....alliwllalyillrvly 111 +vlglsa g+++l lv i p+ ++++dr + ++G+ + w l+++++ a+ + l+f+++ + ++ ++i++++l ++ FUN_000462-T1 2 NVLGLSAENSGWLILQKQLVHTILAPVCAILVDRVHIplvsrKLGKKKTWHLIGTVLHAVVVPLFFAAHYVIPSerserKMMIFFGILNVISGFSN 97 79********************************8643333389***************************999********************** PP MFS_2 112 tffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsg...tkeerkgylifaligaiLmllgviltalgtkervsl 199 t ++++++slv+v++kd+ e +l+++r+ +s+++g+l ++a ++++ s+ e+ + ++++++i + +++ ++ +lgtke + FUN_000462-T1 98 TILQISHLSLVSVIAKDQIEAVELSAIRFGLSYVSGILSFVVAWVILGQDSQsqiSDESSEDFMVLTAILVGVGIFSSMIFYLGTKEPTGA 188 ****************************************************888888899999999999999999999*******98654 PP == domain 2 score: 26.0 bits; conditional E-value: 5.1e-10 MFS_2 215 eqlkevfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglvlalll 309 + +++ ++ l i+ l ++ ++ ++ ++ l ++ + ++ ++ i++++l++ i+a+++ +l +l+++iG+k ++++++l+ + +v+++++ FUN_000462-T1 703 KTIRDWIHDPRLYIVSLAYSCPWAIQVQAYSYLPLLLIFRIRlSQESIAYLPLIMSISATVTAILSKKLVQKIGSKLCFIVSTILVSSSGVITYFM 798 5677888888899999999999999999999999999999999***************************************************** PP MFS_2 310 .qasnlllflvllviagfgvalaallpasmiadvvdygelktGkrregvffavfslisklalalglgvs 377 ++s ++++ ++++ gfg+ ++ + + ++++ +++ + +g++ a +sl+ +++++ ++++ FUN_000462-T1 799 kPESGKVAIYPVVILLGFGFSMMLVNSLGLGTELIGDNK-----KTSGFVVASMSLVASVIGGILIMII 862 766777778888888888888888888888999999998.....7788888888888777666654443 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.8 4.9 0.00046 3.9 27 150 .. 4 160 .. 1 213 [. 0.57 2 ! 44.3 2.8 1.7e-15 1.5e-11 194 343 .. 698 856 .. 667 860 .. 0.77 3 ? -3.8 0.7 0.74 6.3e+03 132 145 .. 887 900 .. 880 908 .. 0.42 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.00046 MFS_1 27 lgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfa.....ss.......lwlllvlrvlqGlgag 100 lg+s+ g+l+ l+ +++++ ++l+dr+ G+++ + l+g++l a++ + l+fa +s + ++ +l v++G+ FUN_000462-T1 4 LGLSAENSGWLILQKQLVHTILAPVCAILVDRVhiplvsrklGKKKtWHLIGTVLHAVV-VPLFFAahyviPSerserkmMIFFGILNVISGFSNT 98 67777777777777778888888888888886556666666688887778888888888.444443233331133333322246666667777777 PP MFS_1 101 alfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfg..............w 150 +l + +l++ +++++ + l+ + g + + + +++ ++++ +g + FUN_000462-T1 99 ILQISHLSLVSVIAKDQIEAVELSAIRFGLSYVSGILSFVVAWVI--LGqdsqsqisdessedF 160 777777777777777766666666555555555555555555555..22234555555544443 PP == domain 2 score: 44.3 bits; conditional E-value: 1.7e-15 MFS_1 194 p.....awkallrdpvlw.lllalllfglaffalltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaa 282 +++ +dp+l+ + la+ + +++ + +++lpl+ + + ls ++++l+ ++++ + ++++l+ +l++++g++ ++++ +l+ ++ FUN_000462-T1 698 RltkekTIRDWIHDPRLYiVSLAYSCPWAIQVQAYSYLPLLlIFRIRLS-QESIAYLPLIMSISATVTAILSKKLVQKIGSKLCFIVSTILVSSSG 792 233445688888999886555555555667777*******999999999.788999999999999999*************999999999999999 PP MFS_1 283 lgllllsltesslwlllallllGfgfglvfplllalvsdla..pkeergtasglyntags.lgg 343 ++ +++ + + ++++ +++llGfgf+++ +++l l ++l+ k+ +g++++ ++++ s +gg FUN_000462-T1 793 VITYFMKPESGKVAIYPVVILLGFGFSMMLVNSLGLGTELIgdNKKTSGFVVASMSLVASvIGG 856 99999999999999999************************44345555566666644443444 PP == domain 3 score: -3.8 bits; conditional E-value: 0.74 MFS_1 132 lGaalGpllgglla 145 l+a++ +++g++l+ FUN_000462-T1 887 LSAIVFSAFGAFLV 900 22222222222222 PP >> DUF6773 Family of unknown function (DUF6773) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.2 0.5 0.0057 48 84 154 .. 49 118 .. 36 123 .. 0.78 2 ? 2.1 0.3 0.026 2.2e+02 89 139 .. 131 181 .. 126 187 .. 0.86 3 ! 19.4 2.7 1.2e-07 0.001 13 152 .. 771 914 .. 768 921 .] 0.72 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0057 DUF6773 84 skknliiglvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfllvvlvilyslakkkskk 154 ++ +li+ ++ ++v+ lff++ +i + ++ + + +f ++ ++s ++++++ + l ++ +ak + + FUN_000462-T1 49 KTWHLIGTVLHAVVVPLFFAAHYVI-PSERSERKMMIFFGILNVISGFSNTILQISHLSLVSVIAKDQIEA 118 3446777888888888999888655.555556899999999999999999999999999999999877655 PP == domain 2 score: 2.1 bits; conditional E-value: 0.026 DUF6773 89 iiglvlglvlalffgirsailygdkykkeaigyfllvflvsfiiylpfllv 139 ++g+++ +v ++ g s + d+++++++ +++ v ++++++f l+ FUN_000462-T1 131 VSGILSFVVAWVILGQDSQSQISDESSEDFMVLTAILVGVGIFSSMIFYLG 181 678888888889999999999999999999999999999999999999875 PP == domain 3 score: 19.4 bits; conditional E-value: 1.2e-07 DUF6773 13 lknKIyseayilviiilllSilvksfvldasleqyltEliilivaglYysvRsvtlG...develhdrkskkslskknliiglvlglvlalffgir 105 l +KI+s + ++v il+ S v +++++ + ++++ ++++++ + ++ +lG + + ++++s + + ++ l+ +++ g+++ ++ + FUN_000462-T1 771 LVQKIGSKLCFIVSTILVSSSGVITYFMKPESGKVAIYPVVILLGFGFSMMLVNSLGlgtELIGDNKKTSGFVVASMSLVASVIGGILIMIIQELF 866 568**************************9999988876666666556555555555558888889999999999999999999999999998888 PP DUF6773 106 sailygdk.ykkeaigyfllvflvsfiiylpfllvvlvilyslakkks 152 ++ +d + ++ + +l + +++f +fl+++l +++ + k s FUN_000462-T1 867 PEQRGTDCkECGDYLQLVLSLSAIVFSAFGAFLVLLLYCINRFQGKSS 914 878877773445555555555555555555555555555555554444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (921 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1133 (0.0443531); expected 510.9 (0.02) Passed bias filter: 566 (0.022157); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.44u 0.40s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 8837.75 // Query: FUN_000464-T1 [L=152] Description: FUN_000464 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-09 36.3 2.2 4.7e-09 36.1 2.2 1.0 1 MFS_1 Major Facilitator Superfamily 2.5e-06 26.8 1.1 2.9e-06 26.6 1.1 1.0 1 MFS_2 MFS/sugar transport protein 0.0026 17.2 1.1 0.0031 17.0 1.1 1.2 1 Sugar_tr Sugar (and other) transporter Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.1 2.2 5.6e-13 4.7e-09 198 327 .. 17 144 .. 6 147 .. 0.82 Alignments for each domain: == domain 1 score: 36.1 bits; conditional E-value: 5.6e-13 MFS_1 198 allrdpvlwlllalllfglaffalltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgllllslte 292 +++++ + + +a+ +++++ + +++lpl+ + +l ls ++++l+ ++++ +a+++ll+ ++++++g++ +++a +++ ++++ +++ + + FUN_000464-T1 17 QMFSHTQV-A-IAYSCSWTLQSHGYSYLPLLlIYRLRLS-KDSIAYLPLIMSISAAVSSLLSKKFVQKIGNKLCFIFATISVSSSGVMTYFMEPES 109 44444444.4.444444456666*******999999999.566777777777777777*************************************9 PP MFS_1 293 sslwlllallllGfgfglvfplllalvsdlapkee 327 s +++ a++llGfgf+l+ +++l++ ++l++ ++ FUN_000464-T1 110 SEKLIYPAVILLGFGFSLMHVNSLNFGTELIGDNK 144 ************************99999987665 PP >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 1.1 3.4e-10 2.9e-06 219 337 .. 17 134 .. 9 146 .. 0.86 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 3.4e-10 MFS_2 219 evfrnrallilllvfllaalamgvlnalllYymryvlg.agfaisvfllvltigallalplvpalakriGkkntyllgillaivglvlalll.qas 312 ++f++ + +++ ++ ++ + ++ l ++ y l+ +++ i++++l++ i+a ++++l +++++iG+k ++++++ + + +v+++++ ++s FUN_000464-T1 17 QMFSHTQ---VAIAYSCSWTLQSHGYSYLPLLLIYRLRlSKDSIAYLPLIMSISAAVSSLLSKKFVQKIGNKLCFIFATISVSSSGVMTYFMePES 109 5555555...57789999999999999999**************************************************************8777 PP MFS_2 313 nlllflvllviagfgvalaallpas 337 + l++ ++++ gfg+ l+ + FUN_000464-T1 110 SEKLIYPAVILLGFGFSLMHVNSLN 134 8888888999999998888766555 PP >> Sugar_tr Sugar (and other) transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 1.1 3.6e-07 0.0031 47 117 .. 56 126 .. 6 132 .. 0.79 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 3.6e-07 Sugar_tr 47 ltglivsiflvGaiiGslfagllgdrfGRkkslliaivlfvigavlqaaakgkksvellivgRvlvGigvG 117 ++ + i+++ a+++sl++ ++++++G+k ++++a++ ++ ++v++++ + ++s l++ + +l+G+g FUN_000464-T1 56 SIAYLPLIMSISAAVSSLLSKKFVQKIGNKLCFIFATISVSSSGVMTYFMEPESSEKLIYPAVILLGFGFS 126 55566679******************************************988777777778888898865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (152 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 786 (0.0307692); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1545.01 // Query: FUN_000465-T1 [L=730] Description: FUN_000465 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-15 57.8 6.0 1.4e-15 57.2 6.0 1.1 1 MFS_2 MFS/sugar transport protein 3.3e-06 26.7 7.6 4.8e-06 26.2 7.6 1.2 1 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.088 12.7 1.2 0.22 11.4 1.2 1.7 1 DUF7987 Family of unknown function (DUF7987) 1.1 10.1 7.7 6.7 7.6 0.6 2.7 2 DUF3382 Domain of unknown function (DUF3382) Domain annotation for each model (and alignments): >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.2 6.0 2.3e-19 1.4e-15 17 197 .. 49 243 .. 33 264 .. 0.82 Alignments for each domain: == domain 1 score: 57.2 bits; conditional E-value: 2.3e-19 MFS_2 17 atyllyFytdvlglsaaavglvllvarlvDvitdpivGaiidr.....trtrwGrrrPwlllsaiilalsfillftppelsqa.......alliwl 100 ++ l +F +vlglsa +g+++l lv v++ p+ + ++dr ++ ++Gr ++w l+++ ++++++ l+f+++ l q +li++ FUN_000465-T1 49 SFRLVLF-MNVLGLSAENAGWLVLQKQLVHVVMAPVCAMLVDRvyiplLSRKYGRKKSWHLIGTFLQTVFIPLFFAAHYLIQNdndqteqMMLIYF 143 4444444.57*********************************333333579***************************999999*********** PP MFS_2 101 lalyillrvlytffevpyvslvpvltkdydeRtkltsvreffstlggllvallafllvlilsgtkeerkgylifaligaiLmllgviltal...gt 193 ++l ++l ++++++++sl++v +kd+ e +l++ r f++l+g+l ++ ++++ s ++++ f+++ aiL+++gv+l+ l gt FUN_000465-T1 144 GILNVILGFGDSMLDISHLSLISVVAKDQIEAVELSALRTAFTYLSGILTFVVSWVILGQGSKSQLSANSSKDFTVLTAILVAVGVLLSLLfhvGT 239 ***********************************************9999999888777777566666666666666666666666664411156 PP MFS_2 194 kerv 197 ke FUN_000465-T1 240 KEPS 243 6554 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 7.6 7.5e-10 4.8e-06 3 187 .. 35 250 .. 33 291 .. 0.77 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 7.5e-10 MFS_1 3 laaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrf.........Grrr.vlllglllfalglllllfa.....s 83 l+ l+ l+++ll+++ l+++ lg+s+ +g+l+ l+ ++++++ + l+dr+ Gr++ + l+g++l ++ + l+fa + FUN_000465-T1 35 LGHTLNDLTTQLLFSFRLVLFMNVLGLSAENAGWLVLQKQLVHVVMAPVCAMLVDRVyipllsrkyGRKKsWHLIGTFLQTVF-IPLFFAahyliQ 129 5677788888888888777889*********************************64466666666*****************.656664344452 PP MFS_1 84 s........lw.lllvlrvlqGlgagalfpaaaaliadwfpke.ergralgllsagfglGaalGpllggllaslfg.....wrav..Flilailal 162 + + ++ +l v++G+g ++l + +li+ +++++ e +l +a++ l+++l +++ +++ +++ ++ F +l ++++ FUN_000465-T1 130 NdndqteqmMLiYFGILNVILGFGDSMLDISHLSLISVVAKDQiEAVELSALRTAFTYLSGILTFVVSWVILGQGSksqlsANSSkdFTVLTAILV 225 2445555554446888889**********************9526666669999999999999999999999999998777444467888888888 PP MFS_1 163 laavlaalllprpppeskrkkpaee 187 +++vl+ ll+ + +e++ ++ + FUN_000465-T1 226 AVGVLLSLLFHVGTKEPSSSPRMPL 250 8888777888766666666654444 PP >> DUF7987 Family of unknown function (DUF7987) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 1.2 3.5e-05 0.22 10 48 .. 183 235 .. 179 241 .. 0.85 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 3.5e-05 DUF7987 10 lvfvvlAvalwygastl.............td.sswvalgvLlgVGVvvPtll 48 ++f l +l++++s++ ++ +++v+ ++L++VGV++ l+ FUN_000465-T1 183 TAFTYLSGILTFVVSWVilgqgsksqlsanSSkDFTVLTAILVAVGVLLSLLF 235 6777888888888888888899999999995669***************9875 PP >> DUF3382 Domain of unknown function (DUF3382) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 1.4 0.0051 33 14 67 .. 52 105 .. 50 128 .. 0.75 2 ? 7.6 0.6 0.001 6.7 7 72 .. 187 249 .. 179 267 .. 0.73 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0051 DUF3382 14 lvLalpilGlqlvldgtklvvet.rwglvaiavavVfvgqLlrellrqalkarrk 67 lvL++ +lGl ++ g lv+++ +v++ v ++ v + ++ll+++ +++++ FUN_000465-T1 52 LVLFMNVLGLSAENAGW-LVLQKqLVHVVMAPVCAMLVDRVYIPLLSRKYGRKKS 105 89********7777776.5555515566666688888999*******99999554 PP == domain 2 score: 7.6 bits; conditional E-value: 0.001 DUF3382 7 liaallalvLalpilGlqlvldgtklvvetrwglvaiavavVfvgqLlrellrqalkarrklklle 72 ++++l++v++ +ilG + +l +++ + + +++V+vg Ll l+ ++k+ +++++++ FUN_000465-T1 187 YLSGILTFVVSWVILGQ---GSKSQLSANSSKDFTVLTAILVAVGVLLSLLFHVGTKEPSSSPRMP 249 58**************7...8888888888666667777777777777777777766666655555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (730 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 892 (0.0349188); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.40u 0.40s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7041.48 // Query: FUN_000466-T1 [L=1686] Description: FUN_000466 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-26 91.6 6.4 4.7e-10 40.4 0.0 3.4 3 Ank_2 Ankyrin repeats (3 copies) 1.4e-22 79.0 5.4 1.5e-05 25.6 0.1 5.9 5 Ank Ankyrin repeat 2.1e-20 73.3 0.2 1.2e-19 70.9 0.1 2.1 2 SAM_1 SAM domain (Sterile alpha motif) 5.1e-17 62.1 0.5 2.9e-06 27.9 0.0 4.9 5 Ank_4 Ankyrin repeats (many copies) 1.7e-16 60.6 0.2 8.6e-16 58.3 0.1 2.2 2 SAM_2 SAM domain (Sterile alpha motif) 3.8e-16 59.5 1.5 4.9e-05 24.1 0.0 4.6 4 Ank_5 Ankyrin repeats (many copies) 9.1e-13 47.5 4.1 0.029 15.4 0.0 6.4 6 Ank_3 Ankyrin repeat 7.7e-12 45.2 0.3 1.8e-11 44.0 0.3 1.7 1 SH3_2 Variant SH3 domain 1e-10 42.3 0.0 6.1e-10 39.8 0.0 2.3 2 PDZ PDZ domain 1.4e-07 31.6 0.1 3.3e-07 30.4 0.1 1.6 1 PDZ_6 PDZ domain 6.8e-06 26.7 0.0 1.9e-05 25.3 0.0 1.7 1 SAM_Ste50p Ste50p, sterile alpha motif 1.8e-05 24.7 0.1 3.9e-05 23.6 0.1 1.6 1 SH3_1 SH3 domain 0.0017 18.8 0.2 0.0062 17.0 0.2 2.0 1 PDZ_Tricorn Tricorn protease PDZ domain 0.0025 18.6 0.0 0.0053 17.5 0.0 1.6 1 FERM_f0 N-terminal or F0 domain of Talin-head FERM ------ inclusion threshold ------ 0.014 15.8 0.1 0.028 14.8 0.1 1.6 1 SH3_9 Variant SH3 domain 0.05 14.4 0.0 0.14 12.9 0.0 1.8 1 PDZ_2 PDZ domain 0.14 12.9 0.0 0.41 11.4 0.0 1.8 1 SAM_CEP-1_C CEP-1 C-terminal SAM domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 0.0 3.5e-10 5.2e-07 16 90 .] 142 221 .. 127 221 .. 0.84 2 ! 40.4 0.0 3.1e-13 4.7e-10 1 88 [. 161 253 .. 161 255 .. 0.87 3 ! 39.8 2.7 4.7e-13 7e-10 1 87 [. 262 350 .. 262 353 .. 0.88 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 3.5e-10 Ank_2 16 Ll.egadanlqdk.ngetaLhlAakng.hleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 + +g d+n++d+ +get+L +A+ + + e++ +L++ ga ++ +++g +a h Aa g e +k Ll+ ga++n kd FUN_000466-T1 142 MTeKGIDPNFHDDkTGETPLSVAVTKEnSPELIIALVNGGALLDyrTRDGLSAVHKAALAGKAESIKTLLDFGASPNYKD 221 44578999988888*******999866266999****9886677879***********************99*****987 PP == domain 2 score: 40.4 bits; conditional E-value: 3.1e-13 Ank_2 1 LmlAakn.gnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaes.ghleivklLlekgadina 88 L +A+ + +++el+ L+ ga + ++ +g +a+h Aa +g++e +k Ll++ga+ n d++g t+L+y++ + g+ ++++Ll++ a++++ FUN_000466-T1 161 LSVAVTKeNSPELIIALVnGGALLDYRTRDGLSAVHKAALAGKAESIKTLLDFGASPNykDSKGLTPLFYSVLHgGNPYCCEILLNDHAELHV 253 56788864788*******66677777777************************99999999*************98*********77788766 PP == domain 3 score: 39.8 bits; conditional E-value: 4.7e-13 Ank_2 1 LmlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadin 87 ++lA+kng + +++Ll +ga++n +++ g+taLh+Aa n+++e++++Ll ga+ n + +++a +Aa sg+ +++ L+++ d++ FUN_000466-T1 262 IHLACKNGLVQHLEHLLfYGAEINARTESGNTALHVAALNNQEECARVLLFRGAKKNilNFANQSAYEVAAVSGN-KVLAELINNFSDKD 350 69******889999999*******9999**********************77766667668899**********9.99999997755554 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.2 0.0 0.0016 2.3 2 32 .. 157 188 .. 156 189 .. 0.86 2 ! 15.7 0.0 1.3e-05 0.02 1 32 [. 190 221 .. 190 222 .. 0.94 3 ! 13.3 0.2 7.5e-05 0.11 2 32 .. 224 255 .. 223 256 .. 0.92 4 ! 12.7 0.1 0.00012 0.17 6 32 .. 262 288 .. 258 289 .. 0.91 5 ! 25.6 0.1 9.7e-09 1.5e-05 2 32 .. 291 321 .. 290 322 .. 0.90 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0016 Ank 2 GnTPLHlAa.raghlevvklLLkhGAdvnard 32 G TPL +A+ +++++e++ L++ GA ++ r+ FUN_000466-T1 157 GETPLSVAVtKENSPELIIALVNGGALLDYRT 188 99*******99999********5369888876 PP == domain 2 score: 15.7 bits; conditional E-value: 1.3e-05 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 dG ++ H Aa ag e +k LL+ GA++n +d FUN_000466-T1 190 DGLSAVHKAALAGKAESIKTLLDFGASPNYKD 221 799*******99**********77******99 PP == domain 3 score: 13.3 bits; conditional E-value: 7.5e-05 Ank 2 GnTPLHlAa.raghlevvklLLkhGAdvnard 32 G TPL + + + g++ ++++LL+++A ++++d FUN_000466-T1 224 GLTPLFYSVlHGGNPYCCEILLNDHAELHVVD 255 99********************778*999988 PP == domain 4 score: 12.7 bits; conditional E-value: 0.00012 Ank 6 LHlAaraghlevvklLLkhGAdvnard 32 +HlA+++g ++ ++ LL +GA +nar+ FUN_000466-T1 262 IHLACKNGLVQHLEHLLFYGAEINART 288 6****************56******97 PP == domain 5 score: 25.6 bits; conditional E-value: 9.7e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 GnT+LH+Aa ++++e+++ LL +GA n+ + FUN_000466-T1 291 GNTALHVAALNNQEECARVLLFRGAKKNILN 321 9********99**********66**999876 PP >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 1.6 2.5e+03 6 35 .. 1038 1067 .. 1035 1070 .. 0.85 2 ! 70.9 0.1 7.7e-23 1.2e-19 3 63 .. 1618 1678 .. 1616 1679 .. 0.97 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.6 SAM_1 6 edVgeWLesiglgqYadsFrkgyidgetLl 35 +d ++ +s + +++F + +i+ge+++ FUN_000466-T1 1038 FDTSDIVRSQIMTSLEEQFTEDEISGEKVS 1067 67778889999999************9986 PP == domain 2 score: 70.9 bits; conditional E-value: 7.7e-23 SAM_1 3 wsvedVgeWLesiglgqYadsFrkgyidgetLlqlteddLeklgvtllgHrkkIlsaiqrl 63 w + dV++WLesi+++qY+d+Fr++ i g +L++l++ +L++lgv++lgHr+ + +ai +l FUN_000466-T1 1618 WGCDDVCNWLESIKMSQYKDTFRENDIQGSHLPELSKAELKELGVKSLGHRMTLENAIAKL 1678 99********************************************************998 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.43 6.5e+02 18 48 .. 144 176 .. 133 178 .. 0.81 2 ! 7.2 0.0 0.0065 9.8 8 46 .. 169 207 .. 161 208 .. 0.79 3 ! 27.9 0.0 2e-09 2.9e-06 1 50 [] 195 245 .. 195 245 .. 0.93 4 ? 4.9 0.1 0.033 50 8 41 .. 236 269 .. 235 275 .. 0.91 5 ! 24.8 0.2 1.9e-08 2.8e-05 14 50 .] 275 311 .. 262 311 .. 0.81 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.43 Ank_4 18 engadinat.dgngetaLhfAasngn.levlkl 48 e+g+d+n d+ get+L A+ ++n +e + FUN_000466-T1 144 EKGIDPNFHdDKTGETPLSVAVTKENsPELIIA 176 7899999888999*********99964666655 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0065 Ank_4 8 ghlellklLlengadinatdgngetaLhfAasngnlevl 46 + el+ L++ ga ++++ ++g +a+h+Aa+ g e + FUN_000466-T1 169 NSPELIIALVNGGALLDYRTRDGLSAVHKAALAGKAESI 207 5556666777669999****************9987766 PP == domain 3 score: 27.9 bits; conditional E-value: 2e-09 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasng.nlevlklLl 50 +h+Aa +g+ e +k+Ll++ga++n+ d g t+L++ +++g n+ +++ Ll FUN_000466-T1 195 VHKAALAGKAESIKTLLDFGASPNYKDSKGLTPLFYSVLHGgNPYCCEILL 245 59************************************9998988877775 PP == domain 4 score: 4.9 bits; conditional E-value: 0.033 Ank_4 8 ghlellklLlengadinatdgngetaLhfAasng 41 g+ +++ Ll+ a+++ +d++g + +h A++ng FUN_000466-T1 236 GNPYCCEILLNDHAELHVVDHQGKQEIHLACKNG 269 677899**************************99 PP == domain 5 score: 24.8 bits; conditional E-value: 1.9e-08 Ank_4 14 klLlengadinatdgngetaLhfAasngnlevlklLl 50 + Ll +ga+ina+ ++g+taLh Aa+n++ e+++ Ll FUN_000466-T1 275 EHLLFYGAEINARTESGNTALHVAALNNQEECARVLL 311 545557****************************997 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 2 3.1e+03 18 47 .. 1049 1079 .. 1044 1083 .. 0.74 2 ! 58.3 0.1 5.7e-19 8.6e-16 4 65 .. 1618 1678 .. 1615 1679 .. 0.94 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2 SAM_2 18 leqykdnFkdagitgaelllrlteedLk.el 47 + + +++F++ +i+g+++ l+ ++d+k ++ FUN_000466-T1 1049 MTSLEEQFTEDEISGEKVSLKNCKNDIKtSM 1079 567899*********5544776666666555 PP == domain 2 score: 58.3 bits; conditional E-value: 5.7e-19 SAM_2 4 wslesvaeWLrsigleqykdnFkdagitgaelllrlteedLkelGitsvghrkkilkkiqel 65 w ++v++WL+si+++qykd F+++ i g ++l++l++ +LkelG+ s+ghr + ++i +l FUN_000466-T1 1618 WGCDDVCNWLESIKMSQYKDTFRENDIQG-SHLPELSKAELKELGVKSLGHRMTLENAIAKL 1678 66789************************.**********************9999988776 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 0.00012 0.19 11 54 .. 154 196 .. 149 196 .. 0.80 2 ! 24.1 0.0 3.3e-08 4.9e-05 2 53 .. 178 228 .. 177 230 .. 0.92 3 ! 15.6 0.1 1.5e-05 0.022 20 53 .. 262 295 .. 253 295 .. 0.97 4 ! 23.0 0.2 7e-08 0.00011 7 56 .] 282 331 .. 279 331 .. 0.95 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.00012 Ank_5 11 rldgegytpLhvAakygaleivrlLl.angvdlnlkdeegltpld 54 +++ g+tpL vA+ + +++ +++ l + g+ l ++ +gl++++ FUN_000466-T1 154 DKT--GETPLSVAVTKENSPELIIALvNGGALLDYRTRDGLSAVH 196 444..55********666666666666**************9985 PP == domain 2 score: 24.1 bits; conditional E-value: 3.3e-08 Ank_5 2 lengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++ g a l++++++g + h+Aa +g +e ++ Ll++g+++n kd+ gltpl FUN_000466-T1 178 VNGG-ALLDYRTRDGLSAVHKAALAGKAESIKTLLDFGASPNYKDSKGLTPL 228 5555.8999999***************************************8 PP == domain 3 score: 15.6 bits; conditional E-value: 1.5e-05 Ank_5 20 LhvAakygaleivrlLlangvdlnlkdeegltpl 53 +h+A+k+g + ++ Ll +g+ +n+++e+g+t+l FUN_000466-T1 262 IHLACKNGLVQHLEHLLFYGAEINARTESGNTAL 295 7*******************************98 PP == domain 4 score: 23.0 bits; conditional E-value: 7e-08 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 a +n++++ g+t+LhvAa ++ e++r+Ll +g+ n+ ++ +++++++A FUN_000466-T1 282 AEINARTESGNTALHVAALNNQEECARVLLFRGAKKNILNFANQSAYEVA 331 6789999****************************************998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.068 1e+02 2 27 .. 157 182 .. 156 185 .. 0.87 2 ! 7.3 0.0 0.0086 13 1 30 [. 190 218 .. 190 218 .. 0.95 3 ? 4.5 0.1 0.072 1.1e+02 2 30 .. 224 252 .. 223 253 .. 0.78 4 ! 10.8 0.3 0.00062 0.93 6 31 .] 262 286 .. 262 286 .. 0.96 5 ! 15.4 0.0 1.9e-05 0.029 2 28 .. 291 316 .. 290 319 .. 0.91 6 ? -1.6 0.0 7 1.1e+04 3 25 .. 325 345 .. 324 350 .. 0.75 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.068 Ank_3 2 gntpLhlAarngrle.ivklLleklga 27 g+tpL +A+ + + ++ +L++ ga FUN_000466-T1 157 GETPLSVAVTKENSPeLIIALVN-GGA 182 99***********9669999999.665 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0086 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 dg ++ h Aa+ g+ e +k Ll+ +ga++n FUN_000466-T1 190 DGLSAVHKAALAGKAESIKTLLD-FGASPN 218 6899*******************.***997 PP == domain 3 score: 4.5 bits; conditional E-value: 0.072 Ank_3 2 gntpLhlAarngrle.ivklLleklgadin 30 g tpL++ +++g + ++ Ll+ +a+++ FUN_000466-T1 224 GLTPLFYSVLHGGNPyCCEILLN-DHAELH 252 89*************45555555.888776 PP == domain 4 score: 10.8 bits; conditional E-value: 0.00062 Ank_3 6 LhlAarngrleivklLleklgadina 31 +hlA++ng ++ ++ Ll +ga+ina FUN_000466-T1 262 IHLACKNGLVQHLEHLLF-YGAEINA 286 5*****************.*****96 PP == domain 5 score: 15.4 bits; conditional E-value: 1.9e-05 Ank_3 2 gntpLhlAarngrleivklLleklgad 28 gnt+Lh+Aa+n++ e +++Ll +ga+ FUN_000466-T1 291 GNTALHVAALNNQEECARVLLF-RGAK 316 9********************9.9987 PP == domain 6 score: -1.6 bits; conditional E-value: 7 Ank_3 3 ntpLhlAarngrleivklLlekl 25 +++ +Aa +g+ + L++ + FUN_000466-T1 325 QSAYEVAAVSGNKV-LAELIN-N 345 6777799*****95.777777.4 PP >> SH3_2 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.0 0.3 1.2e-14 1.8e-11 1 54 [. 512 564 .. 512 565 .. 0.93 Alignments for each domain: == domain 1 score: 44.0 bits; conditional E-value: 1.2e-14 SH3_2 1 ygrvifdyvgtdkngLslkkGdvvkVlggkdddgwwegetgGrkGlvPstavee 54 +++vi+dy ++ + +L+l+kGd v Vl + g+weg++g+ +G++++++v+e FUN_000466-T1 512 RFVVIKDYRPSTAGELALEKGDEVEVL-YVGEKGFWEGRVGNSTGWFHHSCVQE 564 589************************.5566699*****************97 PP >> PDZ PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 4.1 6.1e+03 25 49 .. 512 535 .. 501 535 .. 0.86 2 ! 39.8 0.0 4.1e-13 6.1e-10 3 80 .. 595 682 .. 594 683 .. 0.83 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 4.1 PDZ 25 kgifvsevlpggaaeaggLkaGDrI 49 + +++++ p a e + L++GD++ FUN_000466-T1 512 RFVVIKDYRPSTAGELA-LEKGDEV 535 58999999*********.*****85 PP == domain 2 score: 39.8 bits; conditional E-value: 4.1e-13 PDZ 3 slekegrgglGfslkggsdks...........dkgifvsevlpggaaeaggLkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 +l++ ++ g+Gf+ +g +++ + +v++gg a+ +g++aGD Il+vNg+dv+ +h ++v+++k+s+++v+Lt+ FUN_000466-T1 595 TLQR-NGAGFGFQMRGANSQVprlnfeptpefPALQYFGHVEEGGQAALKGVRAGDFILEVNGEDVTAATHGHVVELIKKSGNSVALTV 682 5666.7778888888877777888888877664445668999**7777777*************************************9 PP >> PDZ_6 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.1 2.2e-10 3.3e-07 5 52 .. 634 682 .. 631 684 .. 0.84 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 2.2e-10 PDZ_6 5 vvpgsPAerAGlrvGDiIlsvNGepv..rsledvarllqgaggesvrllv 52 v++g+ A+ G+r+GD Il+vNGe+v + +v++l++ g sv l+v FUN_000466-T1 634 VEEGGQAALKGVRAGDFILEVNGEDVtaATHGHVVELIK-KSGNSVALTV 682 899**********************9866666*******.5555555555 PP >> SAM_Ste50p Ste50p, sterile alpha motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 1.2e-08 1.9e-05 5 70 .. 1617 1678 .. 1614 1681 .. 0.92 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.2e-08 SAM_Ste50p 5 kWstdevvkkvkaeLgleetdplilriRenditGsvLseltLqDCkeLcdddlkkaiklkllinkl 70 +W d+v+++ ++ + +d++ Rendi+Gs L+el+ ++ keL ++l + + l i kl FUN_000466-T1 1617 DWGCDDVCNWLESIKMSQYKDTF----RENDIQGSHLPELSKAELKELGVKSLGHRMTLENAIAKL 1678 6***********99999999987....**************************9999999999887 PP >> SH3_1 SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.1 2.6e-08 3.9e-05 1 46 [. 514 557 .. 514 557 .. 0.95 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 2.6e-08 SH3_1 1 vAlYDYeaeesdELsfkkGdviivleksedgWwkgrlkdggkeGli 46 v++ DY +++++EL ++kGd+++vl e+g w+gr + +G++ FUN_000466-T1 514 VVIKDYRPSTAGELALEKGDEVEVLYVGEKGFWEGRVGN--STGWF 557 5789**********************************6..6***8 PP >> PDZ_Tricorn Tricorn protease PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.2 4.2e-06 0.0062 37 85 .. 644 691 .. 635 693 .. 0.82 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 4.2e-06 PDZ_Tricorn 37 GvdvreGdlilavdgepvspea.giaelLvgkagqeveLtlrtkdgkarr 85 Gv r+Gd il+v+ge+v++++ g L+ k g++v Lt+ t+ +k+ + FUN_000466-T1 644 GV--RAGDFILEVNGEDVTAAThGHVVELIKKSGNSVALTVITARSKKAS 691 55..58************9865166678**************98876655 PP >> FERM_f0 N-terminal or F0 domain of Talin-head FERM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 3.5e-06 0.0053 3 80 .. 22 99 .. 20 100 .. 0.90 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 3.5e-06 FERM_f0 3 lkislveknvtKtiqFdpetlvkdacklireKvseaelnakdygLFladedgkksvWlesertleyYdlreg.deleYk 80 + i l + +v K +qF+ + v a ++++ ++ + ++ +yg + + +gk +++l+ er+l Y l+ +le+k FUN_000466-T1 22 VLITLPDGRVNKLFQFEVHDKVWAAKLQVMNELKGVK-DVMNYGFYDPPCNGKSGKFLDEERPLIEYPLKGSpPVLEFK 99 568889999**********************999888.8******************************9652577777 PP >> SH3_9 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.1 1.9e-05 0.028 1 48 [. 515 562 .. 515 563 .. 0.89 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.9e-05 SH3_9 1 AlypyqpkeddeLslqeGdvitvieesedgWlegentGrtGlvPanyv 48 ++++y p + eL l++Gd + v+ e+g++eg + +tG + ++v FUN_000466-T1 515 VIKDYRPSTAGELALEKGDEVEVLYVGEKGFWEGRVGNSTGWFHHSCV 562 799*********************7779*******9999998876666 PP >> PDZ_2 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 9.5e-05 0.14 19 68 .. 634 683 .. 603 692 .. 0.88 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 9.5e-05 PDZ_2 19 VksssPaakaglkagDvIlsidgkkvksltdleeallkkkpgdtvklqvl 68 V++++ aa +g++agD Il+++g+ v+ t+ + + l kk g v l+v+ FUN_000466-T1 634 VEEGGQAALKGVRAGDFILEVNGEDVTAATHGHVVELIKKSGNSVALTVI 683 888888999*****************999999999999999999999986 PP >> SAM_CEP-1_C CEP-1 C-terminal SAM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00028 0.41 38 62 .. 1621 1645 .. 1608 1648 .. 0.93 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00028 SAM_CEP-1_C 38 tsiekwLeslgkgsaadkFrkngie 62 + +++wLes+++++++d Fr+n+i+ FUN_000466-T1 1621 DDVCNWLESIKMSQYKDTFRENDIQ 1645 579********************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1686 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1091 (0.0427089); expected 510.9 (0.02) Passed bias filter: 614 (0.024036); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.55u 0.39s 00:00:00.94 Elapsed: 00:00:00.43 # Mc/sec: 15794.43 // Query: FUN_000467-T1 [L=281] Description: FUN_000467 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-09 37.0 38.1 0.00017 22.3 20.5 2.6 2 Dickkopf_N Dickkopf N-terminal cysteine-rich region 0.00021 21.5 14.7 0.0003 21.0 14.7 1.2 1 SR-25 Nuclear RNA-splicing-associated protein ------ inclusion threshold ------ 0.58 11.0 6.3 0.86 10.4 6.3 1.2 1 Lipoprotein_17 Lipoprotein associated domain 0.68 10.8 34.3 0.19 12.6 18.1 3.3 3 DUF7107 Domain of unknown function (DUF7107) Domain annotation for each model (and alignments): >> Dickkopf_N Dickkopf N-terminal cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 20.5 2.7e-08 0.00017 1 51 [] 134 181 .. 134 181 .. 0.94 2 ! 20.0 9.6 1.4e-07 0.00089 2 45 .. 194 244 .. 193 248 .. 0.80 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 2.7e-08 Dickkopf_N 1 eClsDedCgkgkyClssseesvClpcrkrrkrCtrdamCcpgnlCvngvCv 51 eC++D+dC+++k+C++ +C++c + + C + ++Cc+g++C +g Cv FUN_000467-T1 134 ECTKDKDCAANKFCSQFLY--KCQNCID-DFGCFSTRQCCGGKVCKFGRCV 181 7*************99888..****975.799******************6 PP == domain 2 score: 20.0 bits; conditional E-value: 1.4e-07 Dickkopf_N 2 ClsDedCgkgkyClsssees.vClpcrkrrkrCt......rdamCcpgnlC 45 C +D++C++g yC+++ +C+++rk ++rC+ r +C+pg C FUN_000467-T1 194 CNDDRECKAGLYCSYNDFDGgRCVQLRKDGERCNkgmfsrRRPKCAPGLEC 244 **************9999888************722222245678888777 PP >> SR-25 Nuclear RNA-splicing-associated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 14.7 4.6e-08 0.0003 57 149 .. 40 131 .. 16 143 .. 0.49 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 4.6e-08 SR-25 57 kkrrrsssssssssssssssssssssssssgrkkrgkkkdkkrkkkkkkkkkkklkkkkk...ekakaaaakaealpgpsldqWqkealeedGPvl 149 +k++rs ssss+ss ssssssssss ss + k + +k k ++ + +kkk e ++ ++ ++ +p +++ + ++ GP+l FUN_000467-T1 40 AKTKRSESSSSQSSYSSSSSSSSSSDSSGAFHFKVEEYEKKTDKSGTHEVTRTYEKKKPSggnETSNTKTVEVTRFPNGTIQ----RKIKNRGPAL 131 3455555555555555555444443333333322222222222222222333333443331114444444444444444432....2345566666 PP >> Lipoprotein_17 Lipoprotein associated domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 6.3 0.00014 0.86 14 82 .. 38 115 .. 27 117 .. 0.64 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00014 Lipoprotein_17 14 skkntLpSevtnsnlk.nd..nfinfpnssngvsfsikilsnanDenGtLkvkvtl.....skgnks..ksktititGF 82 ++++t+ Se ++s+ + ++ ++ ++++ss f+++ ++ D+ Gt +v+ t+ s gn ++kt+++t F FUN_000467-T1 38 TAAKTKRSESSSSQSSySSssSSSSSSDSSGAFHFKVEEYEKKTDKSGTHEVTRTYekkkpSGGN-EtsNTKTVEVTRF 115 445666666666666534434444444444444555544445**************777754444.146*******998 PP >> DUF7107 Domain of unknown function (DUF7107) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 18.1 3e-05 0.19 1 47 [. 134 181 .. 134 182 .. 0.94 2 ? 6.5 2.6 0.0025 16 26 44 .. 191 209 .. 184 218 .. 0.88 3 ? 0.9 8.2 0.14 8.7e+02 2 32 .. 194 229 .. 193 248 .. 0.65 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 3e-05 DUF7107 1 eCkkhedCkgqeiCvk..gkCvaaeptgkkCksdsdCkkeeaCkygiCw 47 eC+k++dC ++ C++ kC++ + C s+++C +++Ck+g+C+ FUN_000467-T1 134 ECTKDKDCAANKFCSQflYKCQNCID-DFGCFSTRQCCGGKVCKFGRCV 181 6***************999**99877.789******************7 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0025 DUF7107 26 gkkCksdsdCkkeeaCkyg 44 ++ C++d++Ck++ +C y+ FUN_000467-T1 191 KSPCNDDRECKAGLYCSYN 209 578*************985 PP == domain 3 score: 0.9 bits; conditional E-value: 0.14 DUF7107 2 CkkhedCkgqeiCvk.....gkCvaaeptgkkCksd 32 C+++ +Ck C+ g+Cv+ + g++C++ FUN_000467-T1 194 CNDDRECKAGLYCSYndfdgGRCVQLRKDGERCNKG 229 777777777777776666666777777777777754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (281 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1689 (0.0661186); expected 510.9 (0.02) Passed bias filter: 563 (0.0220395); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2808.29 // Query: FUN_000468-T1 [L=379] Description: FUN_000468 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00073 20.3 14.1 0.00073 20.3 14.1 2.9 3 Dickkopf_N Dickkopf N-terminal cysteine-rich region ------ inclusion threshold ------ 0.028 14.8 0.3 0.028 14.8 0.3 2.3 2 DUF6033 Protein of unknown function (DUF6033) 0.21 13.0 0.4 0.21 13.0 0.4 4.5 3 Conotoxin Conotoxin 7.9 8.1 0.0 7.9 8.1 0.0 4.1 4 YxzE YxzE-like putative bacteriocin Domain annotation for each model (and alignments): >> Dickkopf_N Dickkopf N-terminal cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 14.1 1.1e-07 0.00073 1 51 [] 191 242 .. 191 242 .. 0.90 2 ? 1.5 1.7 0.088 5.6e+02 2 36 .. 254 272 .. 246 295 .. 0.53 3 ? -2.4 0.2 1.4 9.3e+03 38 45 .. 316 323 .. 312 337 .. 0.61 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1.1e-07 Dickkopf_N 1 eClsDedCgkgkyClssseesvClpcrkrrkrCtrdamCcpgn...lCvngvCv 51 +C s +dC++gkyC+ vC+++ + + +Ct++++C + n +C +g C+ FUN_000468-T1 191 KCKSSSDCKSGKYCDAFFS--VCKKLSDPGASCTQKNQCDSKNgkyRCTWGRCI 242 6***************999..******************87543339******6 PP == domain 2 score: 1.5 bits; conditional E-value: 0.088 Dickkopf_N 2 ClsDedCgkgkyClssseesvClpcrkrrkrCtrd 36 C +D++C + ++++ +C+++ FUN_000468-T1 254 CDADTECH---------------S-NDEELSCQQQ 272 44455554...............3.3333333333 PP == domain 3 score: -2.4 bits; conditional E-value: 1.4 Dickkopf_N 38 mCcpgnlC 45 C +g C FUN_000468-T1 316 VCKEGLAC 323 45555555 PP >> DUF6033 Protein of unknown function (DUF6033) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.3 4.3e-06 0.028 123 159 .. 17 55 .. 7 118 .. 0.86 2 ? -0.2 5.2 0.16 1e+03 110 142 .. 341 373 .. 338 379 .] 0.71 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 4.3e-06 DUF6033 123 riekkrakkkeekkaeekkaekk..kkeekleekkeekk 159 +i++k+akk e++k+e k++e++ +++ek+e+ ++e++ FUN_000468-T1 17 QINAKKAKKHEAQKEETKQSEEEtkQSDEKIEQPEDEDE 55 688999999999999999998665577888888888776 PP == domain 2 score: -0.2 bits; conditional E-value: 0.16 DUF6033 110 favlekssaaqkeriekkrakkkeekkaeekka 142 fa ++ + +q+e ++k+ k + +kk+++ k+ FUN_000468-T1 341 FASTDEPQPEQSETFTEKKTKTQDKKKNDKNKK 373 888999999999999777776666555555443 PP >> Conotoxin Conotoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.4 3.3e-05 0.21 3 47 .. 4 43 .. 2 56 .. 0.51 2 ? -14.4 18.5 4 2.6e+04 47 64 .. 195 211 .. 178 270 .. 0.64 3 ? -0.5 1.4 0.57 3.6e+03 23 45 .. 351 373 .. 341 378 .. 0.48 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 3.3e-05 Conotoxin 3 LtivlivavLllttlatadldgdqpakrkakaledrkseeksklk 47 L v+iv++ l++ ++ ++++++k +a++ e ++see+ k++ FUN_000468-T1 4 LL-VFIVLLALAS----LQINAKKAKKHEAQKEETKQSEEETKQS 43 33.5555555555....5555555555555555555544444433 PP == domain 2 score: -14.4 bits; conditional E-value: 4 Conotoxin 47 krrCeesgeyCekakkeC 64 +++C++ g+yC+ + C FUN_000468-T1 195 SSDCKS-GKYCDAFFSVC 211 333333.33443222222 PP == domain 3 score: -0.5 bits; conditional E-value: 0.57 Conotoxin 23 dgdqpakrkakaledrkseeksk 45 + ++ +++k+k + ++k+++++k FUN_000468-T1 351 QSETFTEKKTKTQDKKKNDKNKK 373 33333444444444444444444 PP >> YxzE YxzE-like putative bacteriocin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.0012 7.9 9 46 .. 5 44 .. 1 55 [. 0.56 2 ? -7.4 10.4 4 2.6e+04 36 49 .. 185 200 .. 99 219 .. 0.66 3 ? -2.4 0.1 2.3 1.5e+04 35 35 .. 253 253 .. 218 282 .. 0.49 4 ? -2.5 1.5 2.4 1.6e+04 24 31 .. 363 370 .. 352 377 .. 0.46 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0012 YxzE 9 lvfiliiiilavltsskskkkkkrssydhdsss..dsssD 46 lvfi + +++++ +++k+ kk + ++ +++s+ ++sD FUN_000468-T1 5 LVFIVLLALASLQINAKKAKKHEAQKEETKQSEeeTKQSD 44 4566666666665555554444444422444445655555 PP == domain 2 score: -7.4 bits; conditional E-value: 4 YxzE 36 dhdsss....dsssDcgd 49 d +s+ +sssDc + FUN_000468-T1 185 D--TSEeekcKSSSDCKS 200 2..222234677777765 PP == domain 3 score: -2.4 bits; conditional E-value: 2.3 YxzE 35 y 35 + FUN_000468-T1 253 F 253 1 PP == domain 4 score: -2.5 bits; conditional E-value: 2.4 YxzE 24 skskkkkk 31 +++kk+ k FUN_000468-T1 363 QDKKKNDK 370 22222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (379 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2771 (0.108475); expected 510.9 (0.02) Passed bias filter: 959 (0.0375416); expected 510.9 (0.02) Passed Vit filter: 129 (0.00504991); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.42s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 3654.46 // Query: FUN_000469-T1 [L=213] Description: FUN_000469 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00014 22.6 17.5 0.00014 22.6 17.5 3.7 3 Dickkopf_N Dickkopf N-terminal cysteine-rich region ------ inclusion threshold ------ 7 7.6 33.5 0.18 12.7 17.5 3.2 3 DUF7107 Domain of unknown function (DUF7107) Domain annotation for each model (and alignments): >> Dickkopf_N Dickkopf N-terminal cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 17.5 1.1e-08 0.00014 1 51 [] 73 119 .. 73 119 .. 0.96 2 ? -0.9 6.7 0.24 3.1e+03 2 33 .. 131 167 .. 126 169 .. 0.54 3 ? -0.6 0.6 0.19 2.4e+03 8 23 .. 189 207 .. 180 212 .. 0.61 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 1.1e-08 Dickkopf_N 1 eClsDedCgkgkyClssseesvClpcrkrrkrCtrdamCcpgnlCvngvCv 51 eC +dC+ gk+C+ + +C++c ++ C+ Cc+g +C +g+C+ FUN_000469-T1 73 ECNVHKDCPPGKFCDVH----TCRDCLHEHAACHFIGTCCEGFVCQYGHCT 119 6999**********986....79***************************6 PP == domain 2 score: -0.9 bits; conditional E-value: 0.24 Dickkopf_N 2 ClsDedCgkgkyC.lsssees....vClpcrkrrkrC 33 C + +dC ++ C +++ + vC+p+ ++ ++C FUN_000469-T1 131 CDKTSDCLGKESCcVREISVNthtsVCKPMLNEFESC 167 5555666544444133333334455777766666666 PP == domain 3 score: -0.6 bits; conditional E-value: 0.19 Dickkopf_N 8 CgkgkyClsssees...vC 23 C++g C++ + vC FUN_000469-T1 189 CKDGFQCKNVGTKGlhfVC 207 5556666655555455555 PP >> DUF7107 Domain of unknown function (DUF7107) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 17.5 1.4e-05 0.18 1 48 [] 73 120 .. 73 120 .. 0.97 2 ? 4.9 1.4 0.0039 50 27 41 .. 129 143 .. 122 150 .. 0.75 3 ? -0.6 0.7 0.2 2.5e+03 29 37 .. 189 197 .. 182 209 .. 0.67 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.4e-05 DUF7107 1 eCkkhedCkgqeiCvkgkCvaaeptgkkCksdsdCkkeeaCkygiCwk 48 eC+ h+dC+ + C +C++ + C C ++ +C+yg+C k FUN_000469-T1 73 ECNVHKDCPPGKFCDVHTCRDCLHEHAACHFIGTCCEGFVCQYGHCTK 120 6*********************************************75 PP == domain 2 score: 4.9 bits; conditional E-value: 0.0039 DUF7107 27 kkCksdsdCkkeeaC 41 + C+++sdC +e+C FUN_000469-T1 129 TYCDKTSDCLGKESC 143 678888888877777 PP == domain 3 score: -0.6 bits; conditional E-value: 0.2 DUF7107 29 CksdsdCkk 37 Ck+ +Ck+ FUN_000469-T1 189 CKDGFQCKN 197 555555553 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (213 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 871 (0.0340967); expected 510.9 (0.02) Passed bias filter: 275 (0.0107653); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2081.63 // Query: FUN_000470-T1 [L=226] Description: FUN_000470 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.019 15.5 10.3 0.019 15.5 10.3 3.6 3 Conotoxin_I2 I2-superfamily conotoxins 0.043 14.6 21.3 0.043 14.6 21.3 3.7 3 Dickkopf_N Dickkopf N-terminal cysteine-rich region 0.066 14.1 19.1 0.066 14.1 19.1 2.7 3 UPF0506 UPF0506 Domain annotation for each model (and alignments): >> Conotoxin_I2 I2-superfamily conotoxins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 2.3 0.83 7.1e+03 7 17 .. 85 95 .. 82 104 .. 0.63 2 ? 15.5 10.3 2.3e-06 0.019 1 26 [. 106 131 .. 106 133 .. 0.96 3 ? 4.8 2.0 0.005 42 3 21 .. 137 157 .. 136 160 .. 0.80 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.83 Conotoxin_I2 7 sCssdseCCls 17 C+ +++C ++ FUN_000470-T1 85 ECNAHKPCDQG 95 57777777554 PP == domain 2 score: 15.5 bits; conditional E-value: 2.3e-06 Conotoxin_I2 1 CrpegssCssdseCClseCCsgtCes 26 C +e C+++ +CC+++C +g C++ FUN_000470-T1 106 CLKENVACTQNGQCCKGQCTYGRCKK 131 99**********************85 PP == domain 3 score: 4.8 bits; conditional E-value: 0.005 Conotoxin_I2 3 pegssCssdseCCls..eCCs 21 ++g++C ++++C +CC FUN_000470-T1 137 APGTFCDRHDDCRDPpgTCCV 157 589********9764558996 PP >> Dickkopf_N Dickkopf N-terminal cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 21.3 5.1e-06 0.043 1 50 [. 85 129 .. 85 130 .. 0.92 2 ? -1.3 5.2 0.49 4.2e+03 33 46 .. 142 157 .. 135 183 .. 0.62 3 ? 0.8 1.0 0.1 8.8e+02 20 47 .. 195 221 .. 174 223 .. 0.74 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 5.1e-06 Dickkopf_N 1 eClsDedCgkgkyClssseesvClpcrkrrkrCtrdamCcpgnlCvngvC 50 eC + + C +g+yC+ +C+ c k++ Ct++ +Cc+g C +g C FUN_000470-T1 85 ECNAHKPCDQGRYCHM--F--LCVHCLKENVACTQNGQCCKG-QCTYGRC 129 6999999*******85..5..8********************.6*****9 PP == domain 2 score: -1.3 bits; conditional E-value: 0.49 Dickkopf_N 33 CtrdamC..cpgnlCv 46 C r+++C pg++Cv FUN_000470-T1 142 CDRHDDCrdPPGTCCV 157 5555555333455554 PP == domain 3 score: 0.8 bits; conditional E-value: 0.1 Dickkopf_N 20 esvClpcrkrrkrCtrdamCcpgnlCvn 47 ++ C pc++ + C++ + +++Cv FUN_000470-T1 195 QQACGPCKA-GLVCKQVGIFGVHEICVK 221 348999975.677888888888888875 PP >> UPF0506 UPF0506 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 19.1 7.7e-06 0.066 5 58 .. 83 129 .. 81 130 .. 0.92 2 ? -2.8 1.1 1.4 1.2e+04 28 42 .. 165 179 .. 142 183 .. 0.60 3 ? -1.9 1.4 0.76 6.5e+03 4 4 .. 194 194 .. 157 210 .. 0.64 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 7.7e-06 UPF0506 5 tqeCektvfsPCCenflCqlisleiGtCveClalevdCqtdkeCCsGkCsklkC 58 +qeC+ PC + +C + Cv Cl+ +v C + +CC G+C +C FUN_000470-T1 83 SQECNAHK--PCDQGRYCHMF-----LCVHCLKENVACTQNGQCCKGQCTYGRC 129 69999988..********986.....6***********************9999 PP == domain 2 score: -2.8 bits; conditional E-value: 1.4 UPF0506 28 eiGtCveClalevdC 42 i C++ l+ ++ C FUN_000470-T1 165 HISVCKPPLEENMVC 179 344555555555555 PP == domain 3 score: -1.9 bits; conditional E-value: 0.76 UPF0506 4 l 4 + FUN_000470-T1 194 V 194 1 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (226 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1113 (0.0435702); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2242.78 // Query: FUN_000471-T1 [L=420] Description: FUN_000471 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00087 20.1 19.7 0.00087 20.1 19.7 3.2 3 Dickkopf_N Dickkopf N-terminal cysteine-rich region ------ inclusion threshold ------ 0.49 11.4 1.8 36 5.4 0.1 2.7 3 DUF3837 Domain of unknown function (DUF3837) 1.2 9.1 8.4 0.077 13.1 1.1 2.0 2 FapA Flagellar Assembly Protein A beta solenoid domain Domain annotation for each model (and alignments): >> Dickkopf_N Dickkopf N-terminal cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 19.7 1e-07 0.00087 6 50 .. 271 318 .. 268 319 .. 0.90 2 ? -1.6 5.3 0.58 4.9e+03 2 33 .. 331 367 .. 326 373 .. 0.56 3 ? -1.2 0.2 0.44 3.7e+03 23 45 .. 386 407 .. 379 410 .. 0.67 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1e-07 Dickkopf_N 6 edCgkgkyClsssees...vClpcrkrrkrCtrdamCcpgnlCvngvC 50 ++C++ k C+ +++ +C++c k++ Ct++ +Ccpg+ Cv+g C FUN_000471-T1 271 QECNAHKRCKDPTKYChmfLCVDCLKENVACTQNGQCCPGSECVYGRC 318 6899999999888855888***************************** PP == domain 2 score: -1.6 bits; conditional E-value: 0.58 Dickkopf_N 2 ClsDedCgkgkyClsssees.....vClpcrkrrkrC 33 C +dC++ C + +C+p +++++C FUN_000471-T1 331 CDRQSDCKDPDLCCVRESAInpaisICKPALDEHQTC 367 4445555555555444333345555666666666655 PP == domain 3 score: -1.2 bits; conditional E-value: 0.44 Dickkopf_N 23 ClpcrkrrkrCtrdamCcpgnlC 45 C pc++ + +C++ + +++C FUN_000471-T1 386 CGPCKQ-GLTCKQVGIFGVHQVC 407 778764.5667776666666666 PP >> DUF3837 Domain of unknown function (DUF3837) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.1 0.009 76 54 81 .. 18 45 .. 7 52 .. 0.81 2 ? 5.4 0.1 0.0042 36 30 72 .. 136 178 .. 129 198 .. 0.90 3 ? -2.7 0.0 1.4 1.2e+04 50 63 .. 208 221 .. 189 246 .. 0.61 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.009 DUF3837 54 eldeeadklspedekekkliqilkdyep 81 + +e +ls e+e +k+l ++k+y++ FUN_000471-T1 18 ARSELESNLSEEKEMVKYLHGVIKNYQK 45 555566789999**************85 PP == domain 2 score: 5.4 bits; conditional E-value: 0.0042 DUF3837 30 aaGvvakllgleieedikllelreeldeeadklspedekekkl 72 ++G +++ ++ +++di+ ++++ +++ ++++ + ++ek +k FUN_000471-T1 136 TIGYARQEGNVSKRSDIETEDIQPNISTDIETKFGAKEKDRKT 178 689999999***************************9998875 PP == domain 3 score: -2.7 bits; conditional E-value: 1.4 DUF3837 50 elreeldeeadkls 63 ++++e+ +++d ++ FUN_000471-T1 208 DILNEMTKMLDSMM 221 34444444444333 PP >> FapA Flagellar Assembly Protein A beta solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 1.1 0.1 8.5e+02 159 211 .. 20 49 .. 2 90 .. 0.45 2 ? 13.1 1.1 9e-06 0.077 122 266 .. 144 289 .. 142 293 .. 0.79 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.1 FapA 159 eeleeelkeleeeleklkkklkklpkkaekqldeekkeqleklletkekleee 211 +ele +l e ++e+ ++l+ ++++++kl ++ FUN_000471-T1 20 SELESNLSE-----------------------EKEMVKYLHGVIKNYQKLLKN 49 122222211.......................223333333333333333333 PP == domain 2 score: 13.1 bits; conditional E-value: 9e-06 FapA 122 gnikagkevkakelGselgtkteievgvdepelkekleeleeelkeleeeleklkkklkklpk.kaekqldeekkeqleklletkekleeeleele 216 gn++ +++++++ +++t++e+++g++ k++ + + +++++l + + ++ ++ ++++ e+ ++l++++ t +e++l++ + FUN_000471-T1 144 GNVSKRSDIETEDIQPNISTDIETKFGAK---EKDR-KTFLRNVHSLSATSSQAENVAEIPTRhVGREDILNEMTKMLDSMMSTALLYENSLRQKD 235 56666677777766444555555555555...4444.8999999999999999999977777755599**************************** PP FapA 217 eelkelkeelesk....keeakikvnktvypgvkiqigkksleikreigpctfv 266 ++lk+++ + ++ +++k++v+k++ pg q +++++ k++ ++c ++ FUN_000471-T1 236 KHLKKMERSKLQRrtpaDDDNKVIVKKMISPGYYSQECNAHKRCKDPTKYCHMF 289 ****77766666669966667***********9999999999999999988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (420 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1755 (0.0687023); expected 510.9 (0.02) Passed bias filter: 698 (0.0273243); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4187.28 // Query: FUN_000472-T1 [L=132] Description: FUN_000472 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 494 (0.0193384); expected 510.9 (0.02) Passed bias filter: 456 (0.0178509); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1305.53 // Query: FUN_000473-T1 [L=467] Description: FUN_000473 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-40 139.5 0.4 2e-40 139.0 0.1 1.4 2 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 2.4e-38 133.2 2.6 5e-38 132.1 2.6 1.5 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 139.0 0.1 1.5e-44 2e-40 2 215 .. 30 233 .. 29 234 .. 0.84 2 ? -3.9 0.1 0.83 1.1e+04 162 193 .. 334 365 .. 323 370 .. 0.59 Alignments for each domain: == domain 1 score: 139.0 bits; conditional E-value: 1.5e-44 Neur_chan_LBD 2 erlledlleg..YdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlyn.kad 94 +++l++l Ydk++rP +e+ p+++s+ +++ + ++e+n+e+t+++++kq W+D+rL+ + ++ i ++e+ WlPd+++ n k + FUN_000473-T1 30 TQVLNSLSAPgvYDKRIRPY-HEGPPLNISVYITVVTFGAIKEINMEYTLDIFFKQAWNDPRLTHDLRK--PILLPGNEKENFWLPDTFFLNvKTA 122 577888888888*******7.99******************************************9655..4666666666*************** PP Neur_chan_LBD 95 gehevtekntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakr 190 + h v + n+ +++s++G++ +s +++v++sC++d++ +P+D+q+C l++ S++y+ + +d++w++ek i l d e +e el +++++r FUN_000473-T1 123 KFHRVPAANSRIVISPNGDIELSERLTVSASCRMDLRDYPLDTQTCVLEILSYSYDITAMDYHWDDEK-----AVIILDD--EMSEFELADCQSER 211 ******************************************************************54.....3444443..33444444433344 PP Neur_chan_LBD 191 eekktgsyselsysdvtftltlrRk 215 ++ +y +y+++ +++++rR+ FUN_000473-T1 212 KQV---EYVIGTYTHLVAKFVFRRR 233 333...2333346677799999997 PP == domain 2 score: -3.9 bits; conditional E-value: 0.83 Neur_chan_LBD 162 kkvveeeeidlsdflengewelveveakreek 193 k+++++ +++++ l+ng + ++++++r+++ FUN_000473-T1 334 KEAKDNVKAEMEIGLSNGNRNSMTCPMNRSQS 365 33555556666666666666666666666555 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.1 2.6 3.9e-42 5e-38 1 232 [. 241 462 .. 241 463 .. 0.68 Alignments for each domain: == domain 1 score: 132.1 bits; conditional E-value: 3.9e-42 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 ++ P+ liv+Ls+++F++ +dav+++v+LgIt++Lt +++ ++r+s+Pk+S++++++ YL++ ++fvf +l+e+v+Vl + r+ +++++++ FUN_000473-T1 241 IYSPTFLIVVLSWMSFWISKDAVPARVALGITTVLTIVTLMGSLRNSVPKVSYIKAIDS-YLIVSFIFVFGVLLEYVAVLMHSERKRANKTKKQK 334 699********************************************************.**********************9977766544444 PP Neur_chan_memb 96 .vrklfleklprlllmkrpkeeeeeeassagssskaeelilkksrselkaekqsersglerettestessegkelkqseelspele..kaveevn 187 ++ + ++++ l ++++ + +++ +s+s+ + + +s + ++ + ++ + +++ +++ s++ + ++ ++sp + ++ FUN_000473-T1 335 eAKDNVKAEMEIGLSNGNRNSMTCPMN---RSQSSYSLPLRPQSTHGFPVRSPTAHCLPHKSVLKNSYSRQ-SVPGPAIQHSPYTTnpPQAPFLR 425 044444444444444333322222222...22222222222222333333333333333333333333322.22222234444322003444578 PP Neur_chan_memb 188 fiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvi 232 +i + + ++++ev+ Dr+++i+fp+ f+++++++ FUN_000473-T1 426 YIPSFCLQMSADDEVDI--------FDRIARIFFPLSFFVFNIGY 462 999*************9........9*****************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (467 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1176 (0.0460364); expected 510.9 (0.02) Passed bias filter: 782 (0.0306126); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.43s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 4682.66 // Query: FUN_000474-T1 [L=286] Description: FUN_000474 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-37 129.8 7.3 1.5e-36 127.3 7.3 1.9 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.17 12.3 0.0 1 9.8 0.0 2.0 2 DUF6117 Family of unknown function (DUF6117) 0.33 11.6 1.4 3.4 8.4 0.0 2.4 2 DUF3099 Protein of unknown function (DUF3099) Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 127.3 7.3 1.7e-40 1.5e-36 1 232 [. 60 281 .. 60 282 .. 0.67 Alignments for each domain: == domain 1 score: 127.3 bits; conditional E-value: 1.7e-40 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspst.hkmse 94 ++ P+ liv+Ls+++F++ +dav+++v+LgIt++Lt +++ ++r+s+Pk+S++++++ YL++ ++fvf +l+e+v+Vl + r+ + +k+++ FUN_000474-T1 60 IYSPTFLIVVLSWMSFWISKDAVPARVALGITTVLTIVTLMGSLRNSVPKVSYIKAIDS-YLIMSFIFVFGVLLEYVAVLMHSERKRANtTKKQK 153 699********************************************************.**********************9966554166666 PP Neur_chan_memb 95 wvrklfleklprlllmkrpkeeeeeeassagssskaeeli.lk..ksrselkaekqsersglerettestessegkelkqs....eelspeleka 182 + ++ ++++++ ++++ +++ + ++++++++ + +s + ++ + s+ + +++ +++ s+++ + + + FUN_000474-T1 154 EAKDYATAEMEI--GFSNGNRNFVTCP----VNRSQSSYSlSPwpQSTHGFPVRSPSTLCLPHKSVLKNSHSRQSVA---GpaiqHIPYTTSSPQ 239 666666666664..3333333333322....2222222220220022222333444444444444433333322222...122331122223334 PP Neur_chan_memb 183 veevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvi 232 +++i + + ++++ev+ Dr+++iifp+ fv++++++ FUN_000474-T1 240 APFLRYIPSFCLQMTANDEVDI--------FDRIARIIFPLSFVVFNIGY 281 4456777788888888888887........9*****************99 PP >> DUF6117 Family of unknown function (DUF6117) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.21 1.7e+03 35 59 .. 20 44 .. 9 50 .. 0.77 2 ? 9.8 0.0 0.00012 1 6 63 .. 143 199 .. 138 206 .. 0.85 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.21 DUF6117 35 erryvlcavgrdggdyvltpfghla 59 e c r + +yv+ + hl FUN_000474-T1 20 EFELADCQSERKQVEYVIGTYTHLV 44 5555668889999999999999986 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00012 DUF6117 6 hartnfntllraaedgnlalmecldaatgerryvlcavgrdggdyvltpfghladgnp 63 + r+n + a+d a me + g+r +v c v r + y l+p+ ++g p FUN_000474-T1 143 RKRANTTKKQKEAKDYATAEMEI-GFSNGNRNFVTCPVNRSQSSYSLSPWPQSTHGFP 199 56777777788899999999996.56789********************998888877 PP >> DUF3099 Protein of unknown function (DUF3099) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 1.0 0.077 6.6e+02 15 46 .. 50 78 .. 45 102 .. 0.56 2 ? 8.4 0.0 0.00039 3.4 43 67 .. 119 143 .. 107 152 .. 0.77 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.077 DUF3099 15 rRerrYlilmaiRipclvlavvlysvengwla 46 rR+ Y+++++ +l++ v+ + + w++ FUN_000474-T1 50 RRRLAYSFIQIYSPTFLIV-VLSW--MSFWIS 78 6888899988776555544.4332..233433 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00039 DUF3099 43 gwlalvliviavpLPwvAVviANar 67 ++ ++v +v+L +vAV++ +r FUN_000474-T1 119 YLIMSFIFVFGVLLEYVAVLMHSER 143 45666788889*********96555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (286 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1077 (0.0421609); expected 510.9 (0.02) Passed bias filter: 651 (0.0254844); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.44s 00:00:00.69 Elapsed: 00:00:00.39 # Mc/sec: 2924.46 // Query: FUN_000474-T2 [L=277] Description: FUN_000474 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-34 119.6 1.5 4.2e-34 119.3 1.5 1.2 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr 3.1e-09 37.1 0.2 5.4e-09 36.3 0.2 1.4 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin ------ inclusion threshold ------ 0.16 12.4 0.0 0.99 9.9 0.0 2.0 2 DUF6117 Family of unknown function (DUF6117) 0.33 11.6 1.4 3.2 8.4 0.0 2.3 2 DUF3099 Protein of unknown function (DUF3099) Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 119.3 1.5 6.7e-38 4.2e-34 1 102 [. 86 187 .. 86 247 .. 0.89 Alignments for each domain: == domain 1 score: 119.3 bits; conditional E-value: 6.7e-38 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspst.hkmse 94 ++ P+ liv+Ls+++F++ +dav+++v+LgIt++Lt +++ ++r+s+Pk+S++++++ YL++ ++fvf +l+e+v+Vl + r+ + +k+++ FUN_000474-T2 86 IYSPTFLIVVLSWMSFWISKDAVPARVALGITTVLTIVTLMGSLRNSVPKVSYIKAIDS-YLIMSFIFVFGVLLEYVAVLMHSERKRANtTKKQK 179 699********************************************************.**********************9966554156666 PP Neur_chan_memb 95 wvrklfle 102 + ++ +++ FUN_000474-T2 180 EAKDYATA 187 65555554 PP >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.3 0.2 8.4e-13 5.4e-09 128 215 .. 1 78 [. 1 79 [. 0.70 Alignments for each domain: == domain 1 score: 36.3 bits; conditional E-value: 8.4e-13 Neur_chan_LBD 128 idvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakreekktgsyselsysdvtftltlrRk 215 +d++ +P+D+q+C l++ S++y+ +++d++w++ek i l d e +e el +++++r++ +y +y+++ +++++rR+ FUN_000474-T2 1 MDLRDYPLDTQTCVLEILSYSYDISDMDYHWDDEK-----AVIILDD--EMSEFELADCQSERKQV---EYVIGTYTHLVAKFVFRRR 78 89*******************************54.....3444443..34444444533444333...2333346677799999997 PP >> DUF6117 Family of unknown function (DUF6117) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.26 1.6e+03 34 59 .. 45 70 .. 34 76 .. 0.77 2 ? 9.9 0.0 0.00016 0.99 6 63 .. 169 225 .. 164 231 .. 0.85 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.26 DUF6117 34 gerryvlcavgrdggdyvltpfghla 59 +e c r + +yv+ + hl FUN_000474-T2 45 SEFELADCQSERKQVEYVIGTYTHLV 70 55556668889999999999999986 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00016 DUF6117 6 hartnfntllraaedgnlalmecldaatgerryvlcavgrdggdyvltpfghladgnp 63 + r+n + a+d a me + g+r +v c v r + y l+p+ ++g p FUN_000474-T2 169 RKRANTTKKQKEAKDYATAEMEI-GFSNGNRNFVTCPVNRSQSSYSLSPWPQSTHGFP 225 56777777788899999999996.56789********************998888877 PP >> DUF3099 Protein of unknown function (DUF3099) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 1.0 0.098 6.3e+02 15 46 .. 76 104 .. 71 128 .. 0.56 2 ? 8.4 0.0 0.0005 3.2 43 67 .. 145 169 .. 133 178 .. 0.77 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.098 DUF3099 15 rRerrYlilmaiRipclvlavvlysvengwla 46 rR+ Y+++++ +l++ v+ + + w++ FUN_000474-T2 76 RRRLAYSFIQIYSPTFLIV-VLSW--MSFWIS 104 6888899988776555544.4332..233433 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0005 DUF3099 43 gwlalvliviavpLPwvAVviANar 67 ++ ++v +v+L +vAV++ +r FUN_000474-T2 145 YLIMSFIFVFGVLLEYVAVLMHSER 169 45666788889*********96555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (277 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1060 (0.0414954); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2717.21 // Query: FUN_000475-T1 [L=102] Description: FUN_000475 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-24 87.0 0.3 3.2e-24 87.0 0.3 1.0 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.11 13.1 0.1 0.15 12.8 0.1 1.3 1 SRTM1 Serine-rich and transmembrane domain-containi Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.0 0.3 2.5e-28 3.2e-24 7 84 .. 1 77 [. 1 100 [. 0.87 Alignments for each domain: == domain 1 score: 87.0 bits; conditional E-value: 2.5e-28 Neur_chan_memb 7 liviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhh 84 ++v+Ls+l F++p+d+ +++v+Lg t++L+ +f + r++ Pk S+v+++++ Y+++ ++f f++l+e++ +l + FUN_000475-T1 1 MLVVLSWLLFWIPQDSIPARVSLGSTTVLSIVTFTGSFRNTFPKDSYVKAVDV-YFIVSFAFIFAALMEYILLLLNNG 77 789**************************************************.****************98754332 PP >> SRTM1 Serine-rich and transmembrane domain-containing protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 1.1e-05 0.15 30 73 .. 45 91 .. 15 97 .. 0.73 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.1e-05 SRTM1 30 assgrlsnvyvyvs...iflsllaflllllvialqrlkniisssssy 73 s + +vy vs if +l+ ++llll ++r + i s s s FUN_000475-T1 45 DSYVKAVDVYFIVSfafIFAALMEYILLLLNNGFKRKRRIGSESNSQ 91 4456777888766544499*****************99999988775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 905 (0.0354277); expected 510.9 (0.02) Passed bias filter: 527 (0.0206303); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1051.85 // Query: FUN_000476-T1 [L=112] Description: FUN_000476 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-06 28.6 0.2 2.7e-06 28.3 0.2 1.1 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.16 11.4 0.4 0.18 11.2 0.4 1.0 1 MS_TIM-barrel Malate synthase, TIM barrel domain Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.2 2.1e-10 2.7e-06 162 233 .] 22 96 .. 2 96 .. 0.64 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 2.1e-10 Neur_chan_memb 162 essegkelkqs....eelspelekaveevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 +++++e+ q+ ++p + a+ ++ ++ ++++ +++ + + + a++iDr+++++fp ++++++++++ FUN_000476-T1 22 VKDKQQEVPQEleeiIVAKPTSNHAKITATSMTTSVKKVKEYVHYAF-IENEASKIDRVCRYLFPCCYLIFNIFYW 96 33333333333444555555555555555566666666666666555.5668***********************9 PP >> MS_TIM-barrel Malate synthase, TIM barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.4 1.4e-05 0.18 172 232 .. 4 66 .. 1 78 [. 0.81 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 1.4e-05 MS_TIM-barrel 172 qipikddeekneaaleevradKlrevraGadgaWvahPtl..vtlalevfqeelkkvpnqiea 232 q ++k d+ +n +e++ +dK++ev + + va+Pt +++ + +++kkv++ ++ FUN_000476-T1 4 QGRVKYDQVHNVVKVEKIVKDKQQEVPQELEEIIVAKPTSnhAKITATSMTTSVKKVKEYVHY 66 668999********************************9622566667777888888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (112 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1613 (0.0631435); expected 510.9 (0.02) Passed bias filter: 780 (0.0305344); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1121.54 // Query: FUN_000477-T1 [L=431] Description: FUN_000477 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-44 152.9 1.8 1.7e-44 152.3 1.8 1.3 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 2.8e-34 119.9 20.7 2.7e-28 100.3 9.7 2.8 3 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.051 15.0 0.1 0.14 13.6 0.1 1.7 1 DUF4834 Domain of unknown function (DUF4834) 0.057 13.8 0.1 0.15 12.4 0.1 1.7 1 UPF0640 Uncharacterised protein family UPF0640 0.19 12.0 2.1 0.19 12.1 0.4 1.8 2 Saf_2TM SAVED-fused 2TM effector domain Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.3 1.8 3.3e-48 1.7e-44 4 214 .. 34 238 .. 31 240 .. 0.85 Alignments for each domain: == domain 1 score: 152.3 bits; conditional E-value: 3.3e-48 Neur_chan_LBD 4 lledlleg..YdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlyn.kadge 96 +++l+++ Y+k++rP+ ++ p++V++++ + ++ s++e++++++++v+++q+W+D+rLk n ++ i ++ iWlPd+++ n k ++ FUN_000477-T1 34 TIRKLFHEdnYEKRLRPF-HNVAPLNVTVSMAVVHMGSLSEVDMDFSVDVFFRQYWQDPRLKHNLTE--PILLPGYARQAIWLPDTFFLNvKIAKY 126 6788998888*******9.88899***************************************9665..6888888888***************** PP Neur_chan_LBD 97 hevtekntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekk.vveeeeidlsdflengewelveveakre 191 h+v ++n+ ++++sdG+v ws ++++++ C++d++ +P+Deq+C+l+f S++y+ ++vd+ wk +++ v++ e ++++f+ +++ + ++ + FUN_000477-T1 127 HNVPADNSRITIYSDGNVSWSSRITMTANCRLDLRDYPLDEQSCNLTFLSYAYTVNQVDYFWKASESnVIDVIEDEMNEFTLKDIKTRKT----LV 218 ***************************************************************987777777777777777777655554....33 PP Neur_chan_LBD 192 ekktgsyselsysdvtftltlrR 214 e+ t +ys +++ + + l+R FUN_000477-T1 219 EYGTPDYSF---THLWAVFYLNR 238 333333332...33555555555 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.4 0.91 4.6e+03 213 230 .. 2 19 .. 1 20 [. 0.89 2 ! 100.3 9.7 5.3e-32 2.7e-28 1 89 [. 247 334 .. 247 344 .. 0.93 3 ! 27.7 0.1 7.9e-10 4e-06 161 233 .] 348 420 .. 330 420 .. 0.72 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.91 Neur_chan_memb 213 iDrlsliifpivfvlgtl 230 +D l+l+ f+ +++g+ FUN_000477-T1 2 VDLLCLVYFLPWMFIGNS 19 899**********99996 PP == domain 2 score: 100.3 bits; conditional E-value: 5.3e-32 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspst 89 +++P+vliv+Ls+l+F++ +dav+++v+L +t++Lt +++ + r+s+Pk+S+v++l++ ++++ + fvf +++e+viV ++ + +++ FUN_000477-T1 247 IYTPTVLIVMLSWLSFWISKDAVPARVALVVTTVLTIVTLMGSFRSSVPKVSYVKALDV-FFIISLFFVFGAVLEYVIVRLYSEKIKRR 334 79*********************************************************.*******************9998866654 PP == domain 3 score: 27.7 bits; conditional E-value: 7.9e-10 Neur_chan_memb 161 tessegkelkqs.eelspelekaveevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 ++++++++ ++ ++ +++ ++ e+ + i+++ + ++ + ++ + a+ iDr+s+++fpi+f++++++++ FUN_000477-T1 348 SQKRQDNKIYPKgHQTEKHPQSPDENDETIQRNSKMKNIFLKMVY-GNNKANIIDRISRVLFPITFICFNIFYW 420 233233333232445555557777777889999999999999999.6999***********************9 PP >> DUF4834 Domain of unknown function (DUF4834) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 2.8e-05 0.14 8 85 .. 305 386 .. 298 395 .. 0.48 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.8e-05 DUF4834 8 lliiiallvigLsilsvvlravfg..lgrrkkss.......kkkqkqqaksynsaqqkttarsqekeeeeiiveksdekeakhkkki 85 +++ii l+++ ++l+ v+ +++ + rr++s+ qk+q ++ + + ++t++++q+ +e++ ++++++ k +i FUN_000477-T1 305 VFFIISLFFVFGAVLEYVIVRLYSekIKRRSASDrdmvdieMMSQKRQDNKIYPKGHQTEKHPQSPDENDETIQRNSKM----K-NI 386 4555554444444555544444454335666666666666634444444444444444444444444443333333332....2.45 PP >> UPF0640 Uncharacterised protein family UPF0640 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 3e-05 0.15 20 42 .. 304 326 .. 292 334 .. 0.83 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 3e-05 UPF0640 20 GiYrFlPlFFvlGaalEfsminv 42 ++ + lFFv+Ga+lE++++++ FUN_000477-T1 304 DVFFIISLFFVFGAVLEYVIVRL 326 5666788************9875 PP >> Saf_2TM SAVED-fused 2TM effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.4 3.7e-05 0.19 40 98 .. 272 335 .. 226 358 .. 0.76 2 ? -2.1 0.1 0.87 4.4e+03 92 106 .. 375 389 .. 373 395 .. 0.81 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.7e-05 Saf_2TM 40 staltillktaegsveesfqsse.sislvail.iLfigvllivvGalllia..r.yldeakres 98 al + + + + + sf+ss ++s v +l ++fi +l+ v Ga+l+++ r y +++kr+s FUN_000477-T1 272 RVALVVTTVLTIVTLMGSFRSSVpKVSYVKALdVFFIISLFFVFGAVLEYVivRlYSEKIKRRS 335 5688888999999999*******9*****998689************98762242344566654 PP == domain 2 score: -2.1 bits; conditional E-value: 0.87 Saf_2TM 92 deakreskkkiivie 106 ++++r+sk+k+i FUN_000477-T1 375 ETIQRNSKMKNIFLK 389 5799******99765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (431 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1067 (0.0417694); expected 510.9 (0.02) Passed bias filter: 501 (0.0196124); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 4335.33 // Query: FUN_000478-T1 [L=524] Description: FUN_000478 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-38 131.4 0.3 6.3e-38 130.8 0.3 1.2 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 6.6e-30 105.6 4.2 7.8e-29 102.1 4.2 2.3 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.12 12.1 0.3 1 9.1 0.1 2.0 2 MpPF1 M penetrans paralogue family 1 0.77 8.4 4.5 1.1 7.9 4.5 1.1 1 SSP160 Special lobe-specific silk protein SSP160 Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.8 0.3 9.9e-42 6.3e-38 4 215 .. 100 302 .. 97 303 .. 0.91 Alignments for each domain: == domain 1 score: 130.8 bits; conditional E-value: 9.9e-42 Neur_chan_LBD 4 lledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlyn.kadgehe 98 +le ++++Yd+++rP+ + +++ +le+ + ++ +++e++++++++++l q W+D+rL++ + ++i + ek WlPd++++n + +h+ FUN_000478-T1 100 VLEIVFRNYDRRIRPF-YGVQTLHLDLEMLILSFGEISETSMDFEVDLYLGQFWQDPRLAFGIN--KTIILGGASCEKFWLPDTFFVNsIDTRIHK 192 678899*********9.99999***************************************733..34555555555***********55566899 PP Neur_chan_LBD 99 vtekntnvrvss.dGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakreek 193 + ++n++v ++ +G++++s ++++k sC++d++++P+Deq+C+l feS++y+ +++++wk+ e+d f+ +e++ ++ +++++ FUN_000478-T1 193 MVFSNKKVWINLiNGSMMLSARLVTKNSCKLDLRNYPLDEQTCHLAFESFSYEAMDLTYKWKS--------EVDSDIFIYDKEMAQFDIMSAKRHL 280 9999*****9977*************************************************9........899999****999999999888888 PP Neur_chan_LBD 194 ktgsyselsysdvtftltlrRk 215 k++ y ++++s +t+t+++rR+ FUN_000478-T1 281 KHQVYHSETFSGLTATMVFRRR 302 899999999************8 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.1 4.2 1.2e-32 7.8e-29 1 233 [] 310 518 .. 310 518 .. 0.62 Alignments for each domain: == domain 1 score: 102.1 bits; conditional E-value: 1.2e-32 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 ++iPcv iv Ls+++F+++++av+++v+L+It++Lt + + ++++ +P++S+ ++++ +Ll +vf f+ l+e+v Vl + + + + FUN_000478-T1 310 MYIPCVCIVALSWVSFWINHEAVPARVALSITTVLTISYMRGSVNAGMPRVSYLKSIDY-FLLGGFVFIFMTLLEYVLVLKQSR-----KVKLQD 398 6**********************************************************.********************9874.....445555 PP Neur_chan_memb 96 vrklfleklprlllmkrpkeeeeeeassagssskaeelilkksrselkaekqsersglerettestessegkelkqs...eelspelekaveevn 187 ++l + + + +p++ + + + + ++ ++k++ + +g+ + ++s++++++k++ +s +s++++k + +v FUN_000478-T1 399 DEELKNNYQHSKNGGDNPDRRPLQVT-----------VAVDGKSYKFKHSLEDMENGSCPRRKPSIQQRKRKQTLASrlkPLFSKRARKDKPNV- 481 55555554444444444433222211...........111111112222222233333333333333322222222111123333333333322. PP Neur_chan_memb 188 fiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 ++++++ ++++k ++ +D++s+i+fp+ ++ + ++f FUN_000478-T1 482 --LQAVKQR--FRSEK-----GVHYLDQYSRILFPLGYAGFLTIYF 518 ..2333322..22222.....3667999999999998888877776 PP >> MpPF1 M penetrans paralogue family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.063 4e+02 13 52 .. 19 60 .. 17 71 .. 0.81 2 ? 9.1 0.1 0.00016 1 74 117 .. 246 290 .. 232 307 .. 0.77 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.063 MpPF1 13 slskiyd..stgtsrkntneliaedikanlekvFengeelke 52 sls+ y ++++ +++t + ++ i + +++ F n++ + + FUN_000478-T1 19 SLSQCYVvrNSSSGSNSTTTTLTPSITDSPSTSFPNSTTIPD 60 6788887665566678999999**************998765 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00016 MpPF1 74 aYeesknWsastkekkvlYsssskqlnissLn.dLktklskeakl 117 a + + +W+++++++ +Y+++++q++i s + Lk+++ ++++ FUN_000478-T1 246 AMDLTYKWKSEVDSDIFIYDKEMAQFDIMSAKrHLKHQVYHSETF 290 3335678*********************99863799998877665 PP >> SSP160 Special lobe-specific silk protein SSP160 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 4.5 0.00017 1.1 108 324 .. 28 60 .. 4 85 .. 0.43 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.00017 SSP160 108 sssssatstssststtssssttssnsttttsnstsssnstssgltssasvvslidtiawvyqdssvgiaylmvsilalfygqsvsappyadlgipa 203 +sss FUN_000478-T1 28 NSSSG------------------------------------------------------------------------------------------- 32 22222........................................................................................... PP SSP160 204 lpantsgagvpqsvqikaaiayvnvtiyfitltgqqfedlqgpvatdcgcpnttsvaplvleweailaalealasssasanstssststststtts 299 ++s FUN_000478-T1 33 ---------------------------------------------------------------------------------------------SNS 35 .............................................................................................222 PP SSP160 300 tsttttnsttstnstsssnsstiag 324 t+tt t s t + sts ns+ti FUN_000478-T1 36 TTTTLTPSITDSPSTSFPNSTTIPD 60 2222233333333333334433322 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (524 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1105 (0.043257); expected 510.9 (0.02) Passed bias filter: 701 (0.0274418); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 5172.61 // Query: FUN_000479-T1 [L=164] Description: FUN_000479 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-18 64.8 0.0 1.2e-17 64.5 0.0 1.1 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bind Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.5 0.0 4.8e-22 1.2e-17 2 112 .. 43 151 .. 42 161 .. 0.85 Alignments for each domain: == domain 1 score: 64.5 bits; conditional E-value: 4.8e-22 Neur_chan_LBD 2 erlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlyn.kadge 96 ++l++d++e+Ydk+vrP+ + + v+V++++ + ++ +++e n+e++++++l W+D+r + + ++++ +++ W+Pd++++n +++ FUN_000479-T1 43 SNLMSDIMENYDKNVRPF-YGVRSVDVKVDILIFSFGEIKEANMEFSMDLYLGLFWQDPRFQLGLN--QSLTLGGAYTDRFWIPDTFFVNsVQTSV 135 6799*************9.89999************************************999743..35666666666***********555666 PP Neur_chan_LBD 97 hevtekntnvrvssdG 112 he+ +n++v ++ +G FUN_000479-T1 136 HETILPNKKVWINLNG 151 7777899999999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 574 (0.0224702); expected 510.9 (0.02) Passed bias filter: 520 (0.0203562); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1659.28 // Query: FUN_000480-T1 [L=269] Description: FUN_000480 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-34 118.8 3.9 1.9e-33 117.2 3.9 1.7 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 117.2 3.9 7.3e-38 1.9e-33 1 233 [] 32 250 .. 32 250 .. 0.73 Alignments for each domain: == domain 1 score: 117.2 bits; conditional E-value: 7.3e-38 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 +++Pcv iv Ls+++F++++da +++v L+It++Lt +l ++++ lP++S+v++++ +Ll+ + f fl lve+v+Vl ++ r + + ++ FUN_000480-T1 32 MYLPCVCIVALSWVSFWIDPDAIPARVGLSITTVLTICYMLGSVNSNLPRVSYVKAIDY-FLLMSFGFIFLTLVEYVFVLRYSRRMKYVGSFAPG 125 69*********************************************************.**********************9988877666655 PP Neur_chan_memb 96 vrk..lfleklprlllmkrpkeeeeeeassagssskaeelilkksrselkaekqsersglerettestessegkelkqseelspelekaveevnf 188 ++ ++ek ++ + +++ + + s++ ++++ ++ +++ + +++g+++ ++ +++ k+ ++ +p ++k ++ FUN_000480-T1 126 DKThpDLIEKANWRDE---------HNKMEIRISMGGKSYVFTDTLDNAFRGFGGSSKGNKNGRLYKDSGIKNSVIKTVNHSKPVYRKRQN---- 207 5440023333333222.........233456777777777777777654444444444444444444444444444444666665555555.... PP Neur_chan_memb 189 iakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 + r+ + ++ + + ++ iDr ++++fp++++l+ +++f FUN_000480-T1 208 --NDKRSLLQRIRTSFSYNVEGNRIDRSARFLFPFCYLLFLAIYF 250 ..455555555555555566899*****************99998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (269 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 798 (0.031239); expected 510.9 (0.02) Passed bias filter: 424 (0.0165982); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2643.33 // Query: FUN_000481-T1 [L=225] Description: FUN_000481 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-31 110.3 16.7 1.8e-31 110.0 16.7 1.0 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.022 14.5 12.7 0.39 10.4 12.7 2.1 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.076 12.9 14.3 0.086 12.7 14.3 1.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.1 13.0 8.7 0.24 11.8 8.5 1.8 1 DUF2975 Protein of unknown function (DUF2975) 0.11 12.7 10.8 0.23 11.7 10.8 1.5 1 FA_desaturase Fatty acid desaturase Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.0 16.7 3.5e-35 1.8e-31 67 259 .. 1 185 [. 1 186 [. 0.92 Alignments for each domain: == domain 1 score: 110.0 bits; conditional E-value: 3.5e-35 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 67 vnltasillltaisiDRYlaIvkplkykrirtkrralvlilvvWvlalllslppllfsgtktesae.keetvClidfpeeestwevsytlllsvlg 161 ++l+as+ + +ai+++RY+ I +r+ t r+a+ i+++W+l++ + p ++fs+t + + + ke+ +C ++p+ ++++ + ++l+v+ FUN_000481-T1 1 MTLCASVGTFVAIAVERYWHIAM--YKRRKLTVRQAYKAIVIIWLLSVFIPSPIAVFSKTIHWKFNgKEVDICIEQWPN--EKARHLFSTMLFVVL 92 5789*****************76..555689***************************998887778************..669999999999999 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 162 fllpllvilvcyvrilrtlrksakkekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNP 257 +++pl++i+v+y++i r lr+ + +k + + +++k++ +ll+v ++f+lcw+Py++++l+ l ++ + + ++ ++l+ ++l+ +ns+ NP FUN_000481-T1 93 YFIPLSLISVLYWKIGRFLRRLPVMQKATYR----AQKKVTWMLLTVTLLFALCWMPYHVVFLYVDL-TQVTLTPALTSLMLFNQWLISANSACNP 183 ************************9999544....446**************************999.99999*********************** PP xx RF 7tm_1 258 ii 259 i+ FUN_000481-T1 184 IV 185 *8 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 12.7 7.7e-05 0.39 220 318 .. 112 203 .. 3 204 .. 0.75 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 7.7e-05 7TM_GPCR_Srw 220 rkakksrkklskskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifsllltinsisHflicllmSsqYRktvkkl 315 r+ +k + + ++k t + l +T+ f + +p+ +++++ + ++ +++ +l++l+ + ++l+ +ns++ +++ ++ +YR+ +k + FUN_000481-T1 112 RRLPVMQKA-----TYRAQKKVTWMLLTVTLLFALCWMPYHVVFLYVDL--TQVTLTPALTSLMLFNQWLISANSACNPIVFTAFNRNYRRQIKVM 200 333333333.....34577899******************999988444..34579***************************************9 PP 7TM_GPCR_Srw 316 fgc 318 ++ FUN_000481-T1 201 ICK 203 985 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 14.3 1.7e-05 0.086 78 256 .. 9 200 .. 1 201 [. 0.72 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.7e-05 7TM_GPCR_Srsx 78 llLvigiDlliavkfPirYrllskekY...llillifpvlyssiilvlgflqr..ddetiivCapplalagkaseif.tlssliinvivllvylvl 167 +++i++ + +++ r +l ++ Y ++i l+ +++ s i++++ + + + + +C +ka+++f t++ ++++ i l + vl FUN_000481-T1 9 TFVAIAVERYWHIAMYKRRKLTVRQAYkaiVIIWLLSVFIPSPIAVFSKTIHWkfNGKEVDICIEQWPN-EKARHLFsTMLFVVLYFIPLSLISVL 103 566677777777777666666666666222455566788888888888887651155589999988876.55665551566667777767777777 PP 7TM_GPCR_Srsx 168 iii.......lkkkkekkkssskkvlkslkvtvvififgWftstilnt.vllalteseevekliqayagilvllsfsqnffVtywrsseYrkafre 255 +++ l +++++ + kkv l ++ ++f ++W+ +++ v l+ ++ +++ + +l+ +++ n +V+ + +++Yr++++ FUN_000481-T1 104 YWKigrflrrLPVMQKATYRAQKKVTWMLLTVTLLFALCWMPYHVVFLyVDLTQVTLTPALTSLMLFNQWLISANSACNPIVFTAFNRNYRRQIKV 199 7776666666666777799999*******************887776515566666677777999999*************************997 PP 7TM_GPCR_Srsx 256 l 256 + FUN_000481-T1 200 M 200 6 PP >> DUF2975 Protein of unknown function (DUF2975) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 8.5 4.8e-05 0.24 11 82 .. 77 148 .. 37 177 .. 0.86 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 4.8e-05 DUF2975 11 peaaylrvpvllvgylalipfqvalvqlwkLlrlirkdriFseanvrrlkviglaaiaisvllvlalvllal 82 +e+a +l+++l++ip+ ++ v wk+ r +r+ + ++a+ r+ k++ ++++++++l++l ++ + + FUN_000481-T1 77 NEKARHLFSTMLFVVLYFIPLSLISVLYWKIGRFLRRLPVMQKATYRAQKKVTWMLLTVTLLFALCWMPYHV 148 45555556699************************************************9999998885544 PP >> FA_desaturase Fatty acid desaturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 10.8 4.4e-05 0.23 69 183 .. 60 178 .. 2 198 .. 0.73 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 4.4e-05 FA_desaturase 69 HrytngpdeDpdtaplasrgrgllryllrlllglllla.wllalllll.warrlarrkrpiksrrrrwrllaalllllawlglwlallllagllll 162 H ++ng + D+ + + +++++ ++ + +l+ +l + + l+ +l++ + r+l+r + ++k r++ ++++ll ++ l+++l+++ +++++l+ FUN_000481-T1 60 HWKFNGKEVDICIEQ--WPNEKARHLFSTMLFVVLYFIpLSLISVLYWkIGRFLRRLPVMQKATYRAQKKVTWMLLTVT-LLFALCWMPYHVVFLY 152 445699999999998..99999999988888888888899999999995555555555555555555888888888875.8999999999888888 PP FA_desaturase 163 .....lwllpllvllfllalvfnyle 183 + l p+l+ l+l+ ++ ++ FUN_000481-T1 153 vdltqVTLTPALTSLMLFNQWLISAN 178 89999999999999999988865444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (225 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1092 (0.0427481); expected 510.9 (0.02) Passed bias filter: 479 (0.0187512); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2241.20 // Query: FUN_000482-T1 [L=402] Description: FUN_000482 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-60 204.8 17.7 2.7e-60 204.5 17.7 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 8.3e-17 61.9 11.0 1e-16 61.6 11.0 1.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 1.9e-05 24.7 9.6 1.9e-05 24.7 9.6 1.7 2 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 2.2e-05 24.4 15.6 0.00067 19.5 15.6 2.5 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 3.6e-05 24.2 14.9 0.00032 21.1 14.9 1.9 1 7tm_4 Olfactory receptor 0.0029 17.8 0.1 0.0076 16.4 0.1 1.4 1 DUF3169 Protein of unknown function (DUF3169) 0.004 17.7 0.7 0.026 15.1 0.3 2.7 2 DUF5993 Family of unknown function (DUF5993) ------ inclusion threshold ------ 1.2 9.6 4.5 5.9 7.3 0.1 3.4 4 DUF6480 Family of unknown function (DUF6480) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 204.5 17.7 8.5e-64 2.7e-60 1 260 [] 48 294 .. 48 294 .. 0.93 Alignments for each domain: == domain 1 score: 204.5 bits; conditional E-value: 8.5e-64 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN lVil+ +rn ++r++tn+f+ nL vaDl v+l+++pf+++y l g+w+fg+vlCk+v ++ v+l++s+ +l+ai+ DRY aIv+pl + FUN_000482-T1 48 GNALVILA-YRNPRMRSVTNLFIANLGVADLTVTLINVPFSVTYPTL-GHWPFGNVLCKVVPFILGVTLFSSVGTLMAIAADRYRAIVHPLLP--R 139 79999987.699**********************************6.********************************************9..5 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkk 192 + r+al++i+++W++a++ +p +++++ + +++C+ +p+ + +++yt++++v +l+pl+vi+v+y++i++ l+ s++ + FUN_000482-T1 140 IRTRHALMIIAAIWTVAFIYPIPLIVYQKYQ-----PADRSCSEAWPS--QSDQEIYTVMIFVSLYLIPLIVISVLYFLICHNLKTSESDTQA--- 225 666***********************98765.....5799********..55999******************************99998877... PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 193 ksarkerkalktllvvvvvfvlcwlPyfilllldsl.lkeceseklvetallitlllayvnsclNPiiY 260 s+r+++ ++++l+vvvv+f++cwlPy+i++l+ + + + k + + ++ ++++++nsc NP++Y FUN_000482-T1 226 GSNRAKKSVIRMLVVVVVLFTMCWLPYHITTLYINFaEFQPRPPKWLVELHMFNMWMMFANSCCNPVVY 294 7788899*****************************855666667777788999**************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.6 11.0 3.2e-20 1e-16 1 256 [. 42 308 .. 42 309 .. 0.79 Alignments for each domain: == domain 1 score: 61.6 bits; conditional E-value: 3.2e-20 7TM_GPCR_Srsx 1 lvvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv..llltgtqlkreeCFlliivyvfgltaqsvllLvigiDlliavkfPi 94 +vvG+iGN l+i l ++++++rs +++ i + +adl + + +++f v +l + ++ C ++ ++ + l+ + l++i+ D+ a+ P+ FUN_000482-T1 42 CVVGTIGNALVI-LAYRNPRMRSVTNLFIANLGVADLTVTLINVPFSVtyPTLGHWPFGNVLCKVVPFILGVTLFSSVGTLMAIAADRYRAIVHPL 136 79******9765.679************************9999998833577777777777766666666666666667999************* PP 7TM_GPCR_Srsx 95 rYrllskek..YllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllv.ylvliiilkkkkek....kksssk 183 r +++ +++ ++ ++y + ++v++ +q d+ p + ++ ++ +s +i +iv+ v y+ + + lk+++++ +++ k FUN_000482-T1 137 LPRIRTRHAlmIIAAIWTVAFIYPIPLIVYQKYQPADRSCSEAWPSQSDQEIYTVMIFVSLYLIPLIVISVlYFLICHNLKTSESDtqagSNRAKK 232 998888777545556667788999999999999988885555555555555555566666667776666541555555566665557888899999 PP 7TM_GPCR_Srsx 184 kvlkslkvtvvififgWf...tstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +v++ l v+vv+f ++W+ ++t+ ++ + ++ +++ ++++++ +++ n +V+ + +++Yr++f++l FUN_000482-T1 233 SVIRMLVVVVVLFTMCWLpyhITTLYINFAEFQPRPPKWLVELHMFNMWMMFANSCCNPVVYAVLNRNYRREFKRL 308 *****************844466666677777778899***********************************997 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 0.63 2e+03 169 191 .. 35 57 .. 29 74 .. 0.79 2 ! 24.7 9.6 5.9e-09 1.9e-05 92 283 .] 120 311 .. 75 311 .. 0.72 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.63 7TM_GPCR_Srv 169 livvvvtciiliiayvllfvvlr 191 l+++++ c++ i ++l++++ r FUN_000482-T1 35 LVFYSIICVVGTIGNALVILAYR 57 68888999998888888888888 PP == domain 2 score: 24.7 bits; conditional E-value: 5.9e-09 7TM_GPCR_Srv 92 givlLslqRllaillPisrltkivqsaklwkiilvywlvgllislvvlkdtdieydneenmpvvadksvierftlialiv.vvvtciiliiayvll 186 + + ++ R+ ai++P l +i + ++l++i ++ w v+++ + + + ++++ + + ++s++e+ t + ++ +++ i+++++y+l+ FUN_000482-T1 120 TLMAIAADRYRAIVHPL--LPRIRTRHALMIIAAI-WTVAFIYPIPLIVYQKYQPADRSCSEAWPSQSDQEIYTVMIFVSlYLIPLIVISVLYFLI 212 5678999**********..8888888777777666.8****999999988877777777789999999999988888776155678899999**** PP 7TM_GPCR_Srv 187 fvvlrkkkkkksqtkskslkrevrLaiqvlilvlaqliilifyilklyfs....qtlntdpifylRalYpilsgl.lsyinPylllilskdlrkqv 277 + l+++++ ++++++++k + v+++vl+ ++ l + i ly++ q + + + l +++++ + s nP + +l+++ r+++ FUN_000482-T1 213 CHNLKTSESDTQAGSNRAKKSV--IRMLVVVVVLFTMCWLPYHITTLYINfaefQPRPPKWLVEL-HMFNMWMMFaNSCCNPVVYAVLNRNYRREF 305 **99966555555555555554..45567777888899999999999988332233333446777.778886654168999999999999999999 PP 7TM_GPCR_Srv 278 lkrlkc 283 + l+c FUN_000482-T1 306 KRLLRC 311 777765 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 15.6 2.1e-07 0.00067 184 319 .] 184 312 .. 36 312 .. 0.70 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 2.1e-07 7TM_GPCR_Srw 184 ndglllkifllidgilskiipsillpiltilLiieLrkakksrkklskskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsil 279 d+ +i++++ +++ +ip i++ +l +l ++L++++ ++ s n+ +++ ++ +++ + f++ lp+ i++++ + + +++ + l FUN_000482-T1 184 SDQ---EIYTVMIFVSLYLIPLIVISVLYFLICHNLKTSESDTQAGS----NRAKKSVIRMLVVVVVLFTMCWLPYHITTLYINFAEFQPRPPKWL 272 223...3344444455568*****************99999998888....34578899999999*****************9999999999**** PP 7TM_GPCR_Srw 280 eelevifsllltinsisHflicllmSsqYRktvkklfgck 319 el ++ +++ +ns++ +++ ++ +YR+ +k+l++c+ FUN_000482-T1 273 VELHMFNMWMMFANSCCNPVVYAVLNRNYRREFKRLLRCQ 312 *************************************995 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 14.9 9.9e-08 0.00032 2 277 .. 39 309 .. 38 312 .. 0.72 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 9.9e-08 7tm_4 2 clvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesavllamavdrfvaiy 97 +++ ++ +Gn+ ++ + + lf+a l ++dl +++ +P + ++ c + f++ + +l+a+a dr+ ai+ FUN_000482-T1 39 SIICVVGTIGNALVILAYRNP-RMRSVTNLFIANLGVADLTVTLINVPFSVTYPTLGHWPFGNVLCKVVPFILGVTLFSSVGTLMAIAADRYRAIV 133 678888899999888887765.5788899*******************9888888887777766776666655555555567899*********** PP 7tm_4 98 splryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsyglilr 193 +pl + i t + ++ i+++ + +v++++p+++++ + ++++ s ++ +++ +iy +++ vs + + ++i + y li + FUN_000482-T1 134 HPLLP-RIRTRHALMIIAAI-W--TVAFIYPIPLIVYQKYQPADRSCSEAWPSQSD-----------QEIYTVMIFVSLYLIPLIVISVLYFLICH 214 ***86.79999988777765.4..45566899888888777888888888765554...........579************************99 PP 7tm_4 194 tvlgia..sreerkkalntcgs.hvcavlaf...yvPmiglsvvhrfgkkvsr....llqvllanlyllfP.PvlnPivysvktkeirdavvkil 277 + + ++++ +a ++ v++v++f + P ++ f++ +r l++ + n++++f nP+vy+v ++ r+ +++l FUN_000482-T1 215 NLKTSEsdTQAGSNRAKKSVIRmLVVVVVLFtmcWLPYHITTLYINFAEFQPRppkwLVELHMFNMWMMFAnSCCNPVVYAVLNRNYRREFKRLL 309 87554311333334443333330334444441124454444444455544333223478999*****99972689**********9999999887 PP >> DUF3169 Protein of unknown function (DUF3169) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.1 2.4e-06 0.0076 53 138 .. 145 249 .. 140 272 .. 0.77 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 2.4e-06 DUF3169 53 liviilalltliflkkakkyk.klvdeeidddlsetyeeqlnrkllkglilvslqlv.laflailiavkgniaen..................llv 128 + +ii a+ t+ f++ + + ++++ d + se q++ + + ++i+vsl+l+ l+++++l +++ ++ + +lv FUN_000482-T1 145 ALMIIAAIWTVAFIYPIPLIVyQKYQPA-DRSCSEAWPSQSDQEIYTVMIFVSLYLIpLIVISVLYFLICHNLKTsesdtqagsnrakksvirMLV 239 678999*********9977651556655.***************************9788899999999999988899************888444 PP DUF3169 129 illvlikfll 138 +++vl ++ FUN_000482-T1 240 VVVVLFTMCW 249 4444444333 PP >> DUF5993 Family of unknown function (DUF5993) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 1.9 6.2e+03 12 22 .. 52 62 .. 48 70 .. 0.73 2 ! 15.1 0.3 8.3e-06 0.026 17 50 .] 229 261 .. 226 261 .. 0.87 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.9 DUF5993 12 vllalrgkrkl 22 v+la+r++r FUN_000482-T1 52 VILAYRNPRMR 62 78999999754 PP == domain 2 score: 15.1 bits; conditional E-value: 8.3e-06 DUF5993 17 rgkrklalalfavtLvislawfkhHiTssLtLsL 50 r k+++ +l++v+++ ++ w+ +HiT L++++ FUN_000482-T1 229 RAKKSVIRMLVVVVVLFTMCWLPYHITT-LYINF 261 56899999******************94.77766 PP >> DUF6480 Family of unknown function (DUF6480) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.2 3.7e+03 45 71 .. 26 52 .. 15 56 .. 0.61 2 ? -1.7 0.1 1.2 3.8e+03 49 73 .. 142 166 .. 134 167 .. 0.73 3 ? 2.1 0.0 0.077 2.5e+02 31 73 .. 171 214 .. 170 218 .. 0.74 4 ? 7.3 0.1 0.0018 5.9 39 75 .. 218 254 .. 213 257 .. 0.80 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.2 DUF6480 45 hnpskgwakaplvlIlvvvvlvavffv 71 ++p+ w +++ I+ vv + ++v FUN_000482-T1 26 QDPELKWLRLVFYSIICVVGTIGNALV 52 566667777776666666655544444 PP == domain 2 score: -1.7 bits; conditional E-value: 1.2 DUF6480 49 kgwakaplvlIlvvvvlvavffvay 73 ++ a +++++I+ v+ + + +++y FUN_000482-T1 142 TRHALMIIAAIWTVAFIYPIPLIVY 166 6667788888888887777766665 PP == domain 3 score: 2.1 bits; conditional E-value: 0.077 DUF6480 31 Paesstsgagpre.thnpskgwakaplvlIlvvvvlvavffvay 73 Pa+ s s+a p++ ++ + + + l lI ++v+ v f++ + FUN_000482-T1 171 PADRSCSEAWPSQsDQEIYTVMIFVSLYLIPLIVISVLYFLICH 214 78888888877773455566777788888999999988888865 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0018 DUF6480 39 agprethnpskgwakaplvlIlvvvvlvavffvayav 75 +++++t+ s++ +k ++ +++vvvvl+ + + y + FUN_000482-T1 218 TSESDTQAGSNRAKKSVIRMLVVVVVLFTMCWLPYHI 254 5666777888889999999999999999988888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1324 (0.0518301); expected 510.9 (0.02) Passed bias filter: 638 (0.0249755); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 3859.94 // Query: FUN_000483-T1 [L=636] Description: FUN_000483 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-17 62.5 0.0 2.6e-16 59.6 0.0 2.6 2 DUF3719 Protein of unknown function (DUF3719) Domain annotation for each model (and alignments): >> DUF3719 Protein of unknown function (DUF3719) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.6 0.0 1e-20 2.6e-16 1 62 [. 117 180 .. 117 184 .. 0.84 2 ? -1.6 0.0 0.13 3.3e+03 31 43 .. 464 476 .. 463 497 .. 0.80 Alignments for each domain: == domain 1 score: 59.6 bits; conditional E-value: 1e-20 DUF3719 1 mLfEgKvspqtqnLqaECqeWarrfpHLRilGrqlilPtDeGfqlyqspspss..asseallsa 62 mLfEg + + +L EC+eW +rfpHLRi+G+ql+ ++D+G+q + p+ s + +++++s+ FUN_000483-T1 117 MLFEGESFNGSAQLLCECEEWFQRFPHLRICGHQLMISNDDGTQQIPVPADDSflYGERPQTSV 180 9********************************************9977555411445566555 PP == domain 2 score: -1.6 bits; conditional E-value: 0.13 DUF3719 31 lGrqlilPtDeGf 43 G++l++++D+G FUN_000483-T1 464 QGKKLLTSSDKGS 476 6999999999995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (636 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 661 (0.0258759); expected 510.9 (0.02) Passed bias filter: 500 (0.0195733); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.39u 0.36s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 6170.00 // Query: FUN_000485-T1 [L=128] Description: FUN_000485 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 551 (0.0215698); expected 510.9 (0.02) Passed bias filter: 443 (0.0173419); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1287.72 // Query: FUN_000486-T1 [L=360] Description: FUN_000486 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.056 13.1 5.6 0.31 10.7 1.4 2.2 2 Peptidase_M56 BlaR1 peptidase M56 0.93 9.4 10.5 0.58 10.1 0.5 2.6 3 DUF3671 Fam-L, Fam-M like protein Domain annotation for each model (and alignments): >> Peptidase_M56 BlaR1 peptidase M56 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.2 0.0019 24 36 130 .. 75 164 .. 67 192 .. 0.67 2 ? 10.7 1.4 2.4e-05 0.31 27 137 .. 220 329 .. 214 341 .. 0.68 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.0019 Peptidase_M56 36 lWlivllalvaplipesavsnvetsaasiaaskaplnsaaakviddkasalatdvkavewstilkillllWivgalilllyliaallvlrkrfvr 130 lW+ + + ++p+++ +s ++ + k + +++++v+ + + + +v+ ++ ++l + +v +++++ + +++ r + + FUN_000486-T1 75 LWSFLSVLFTIPIMM---MSLIGEAVIVFYCDKKSALKSNSTVTFCRKTRGDLRDLSVDEYEVYQFLRFIAVVAQVVCFVSMCISVRRSRYK--S 164 788888888888888...44334444444444445555555555566667777777777888888899999999999999999998844433..2 PP == domain 2 score: 10.7 bits; conditional E-value: 2.4e-05 Peptidase_M56 27 llsataaYalWlivllalvaplipesavsnvetsaasiaaskaplnsaaakviddkasalatdvkavewstilkil...lllWivgalilllylia 119 +ls +a lWl+v+ +lv + + + a+ + ++ +++i + + + a + ++ t++++++ + + + + W++g +++++ + FUN_000486-T1 220 MLSILWAIVLWLTVISCLVYATVINGAIAQAKQGNQQIMNLDEGTVNDAI---EIHQRICRTSMRTIKLYHTWFLInsaCYFWLIGYVAVVFLTQS 312 56667888899999999999999988888777777666665555544444...45777888888888888887777655799*****995555444 PP Peptidase_M56 120 allvlrkrfvrklgklra 137 + + ++ ++ +l+ +++ FUN_000486-T1 313 SHMHSWS-MFYHLSVCDN 329 4443333.4555555555 PP >> DUF3671 Fam-L, Fam-M like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 1.2 0.0017 21 149 211 .. 44 104 .. 35 107 .. 0.76 2 ? 10.1 0.5 4.5e-05 0.58 154 209 .. 175 241 .. 167 244 .. 0.90 3 ? -2.1 0.1 0.24 3e+03 143 180 .. 272 309 .. 261 342 .. 0.61 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0017 DUF3671 149 ktlkkiirkkyglrialpllflllllllsllldlslfgiliylvpfiilgiiiilgiiyilkK 211 +tl+++++k ++ + l ++ + +l + l f ++++ +p++++++i +i++++ K FUN_000486-T1 44 NTLQRLLFKIISSGMLLKYIACISGLWVGSH--LWSFLSVLFTIPIMMMSLIGEAVIVFYCDK 104 5666677777777777777766666666644..34789999******************9987 PP == domain 2 score: 10.1 bits; conditional E-value: 4.5e-05 DUF3671 154 iirkkyglrialpllflllllllsllldls...........lfgiliylvpfiilgiiiilgiiyil 209 ++++k l + l l+ +++ll++s ll++ +g ++ ++ i+l++++i++++y FUN_000486-T1 175 LVKRKKWLSVNLQLIGFFILLVTSNLLNFCcssegpcsscdGVGAMLSILWAIVLWLTVISCLVYAT 241 6788888999999999********999999***********89999999****************75 PP == domain 3 score: -2.1 bits; conditional E-value: 0.24 DUF3671 143 nrtisdktlkkiirkkyglrialpllflllllllslll 180 +++i+ +++ i+ ++i + f l++ + +++l FUN_000486-T1 272 HQRICRTSMRTIKLYHTWFLINSACYFWLIGYVAVVFL 309 55566666666666666666666555555555555443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (360 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1211 (0.0474065); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3494.53 // Query: FUN_000487-T1 [L=369] Description: FUN_000487 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-38 131.7 16.4 5.8e-38 131.3 16.4 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 5.8e-09 36.2 15.6 7.6e-09 35.8 15.6 1.2 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 131.3 16.4 4.5e-42 5.8e-38 2 260 .] 48 296 .. 47 296 .. 0.94 Alignments for each domain: == domain 1 score: 131.3 bits; conditional E-value: 4.5e-42 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrir 97 Nl V+l+++++++lrt n fl++La++Dll++ +++p+ l ++ ++++ +++C+l++ +++nlt+s l+l+++si RYl+I p+ +kr + FUN_000487-T1 48 NLSVVLAFITHRRLRTKVNAFLVSLAISDLLLTGISMPLELEWHI-RSEFIHDAIVCDLLYTTYFLNLTSSSLNLLLLSIYRYLSIAFPFFMKR-V 141 99***************************************7776.899999****************************************75.7 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 98 tkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkkk 193 + +++l+ +++ W+++ + + +p++ g++++ + +++ Cl +f++ +++l++++ +l p ++++++y +i+r +r +a k ++k FUN_000487-T1 142 SSHHVLLALGASWLYSGITASLPIM--GWRRFPT-VTHRKCLYSFEK-------EFILFILTTNWLSPAILVFFFYGLIFRIARIQAIKILKNKIL 227 7899*******************99..8899965.**********99.......99****************************999999885555 PP xxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 194 sarker......kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 e+ k +ktl+ + v+++cw+Py++ +ll + + k+++ + ++++l+y+++++NP++Y FUN_000487-T1 228 TDH-EKirsplfKGAKTLAKIATVYLICWFPYVTEVLLVMA---GAVAKVPSEVHYLFVFLCYTSAAINPFLY 296 543.44479999**********************9999888...9***************************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.8 15.6 6e-13 7.6e-09 1 255 [. 41 309 .. 41 311 .. 0.76 Alignments for each domain: == domain 1 score: 35.8 bits; conditional E-value: 6e-13 7TM_GPCR_Srsx 1 lvvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv.llltgtqlkre.eCFlliivyvfgltaqsvllLvigiDlliavkfPi 94 ++vG+i N+ ++l+++++++Lr+k++ ++ ++++dll+ +++ + ++ + ++ + C ll + y + lt +s+ lL++ i + + ++fP+ FUN_000487-T1 41 CIVGFIANLSVVLAFITHRRLRTKVNAFLVSLAISDLLLTGISMPLELeWHIRSEFIHDAiVCDLLYTTYFLNLTSSSLNLLLLSIYRYLSIAFPF 136 69************************************999999887757777777776637********************************** PP 7TM_GPCR_Srsx 95 rYrllskekYllillifpvlyssiil...vlgflqrddetiivCapplalagkaseiftlssliinvivll..vylvliiilkkkkek........ 177 + +++s++ +l+ l lys i+ ++g + t C + + +k + +f l++ ++ ++l+ y +++i++ + k FUN_000487-T1 137 FMKRVSSH-HVLLALGASWLYSGITAslpIMGWRRFPTVTHRKCLYSF---EKEFILFILTTNWLSPAILVffFYGLIFRIARIQAIKilknkilt 228 *****999.566666666777766551116677777777888888776...457777877777776555540044444444333333366666666 PP 7TM_GPCR_Srsx 178 ....kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafre 255 +s k k l+ ++++++Wf + +l+ +v ++ ++l +s++ n f + +++r+ fr+ FUN_000487-T1 229 dhekIRSPLFKGAKTLAKIATVYLICWFPYVTE-VLLVMAGAVAKVPSEVHYLFVFLCYTSAAINPFLYAGLCKDFRQVFRK 309 532233344444467888899******976554.4445567777788889999999************************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (369 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 811 (0.0317479); expected 510.9 (0.02) Passed bias filter: 389 (0.015228); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3674.02 // Query: FUN_000488-T1 [L=216] Description: FUN_000488 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-52 178.4 3.7 2e-52 178.1 3.7 1.0 1 Ribosomal_L1 Ribosomal protein L1p/L10e family ------ inclusion threshold ------ 0.033 14.9 0.2 0.72 10.7 0.1 2.4 2 RBFA Ribosome-binding factor A Domain annotation for each model (and alignments): >> Ribosomal_L1 Ribosomal protein L1p/L10e family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 178.1 3.7 1.6e-56 2e-52 3 197 .. 21 210 .. 18 211 .. 0.98 Alignments for each domain: == domain 1 score: 178.1 bits; conditional E-value: 1.6e-56 Ribosomal_L1 3 khakakfdesvelalnlkgvdprkadqrvrgtipLphglgkevkvcviakdekaeeakeagiadvvgvedlkekiksfeakrklakefdlfladpr 98 k +k+kf e++el++ lk++dp+k d+r++gt++L++ ++++kvcv+ + +++ea++++ ++ e lk+ k+++ +klak +d+fla+++ FUN_000488-T1 21 KDKKRKFVETIELQISLKNYDPQK-DKRFSGTVKLKNIPRPKLKVCVLGDASHCDEANAND-IPCMDAEALKKLNKNKKLVKKLAKRYDAFLASDS 114 55799****************998.************************************.********************************** PP Ribosomal_L1 99 impllpklLGkvlgprgkmPnpvkgtvtkdvakaveeakkgtvefrvdkggclhvkvGklsfteeqlveNikaviealvkklpkggkniksiylkt 194 +++++p++LG+ l+++gk+P++ + ++++ ++vee+++ t++f+++k cl+v++G++++te+ql++N+ ++++lv+ l+k+++n++++ylk+ FUN_000488-T1 115 LIRQIPRILGPGLNKAGKFPTALT--HNDNMVQKVEEVRS-TIKFQMKKVLCLAVAIGHVEMTEDQLIANVYLAVNFLVSLLKKNWQNVRALYLKS 207 ***********************8..589***********.******************************************************* PP Ribosomal_L1 195 tmg 197 tmg FUN_000488-T1 208 TMG 210 **9 PP >> RBFA Ribosome-binding factor A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.029 3.7e+02 57 74 .. 85 102 .. 63 121 .. 0.81 2 ? 10.7 0.1 5.6e-05 0.72 11 50 .. 148 186 .. 140 210 .. 0.77 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.029 RBFA 57 keevlkaLnkaagfirse 74 +e+lk+Lnk+++ +++ FUN_000488-T1 85 DAEALKKLNKNKKLVKKL 102 568999*****9988764 PP == domain 2 score: 10.7 bits; conditional E-value: 5.6e-05 RBFA 11 relseilqkeikdprlgklvtvteVevskDlshakvyvsv 50 +e+ + ++ ++k+ v + +Ve+++D +a+vy+ v FUN_000488-T1 148 EEVRSTIKFQMKKVLC-LAVAIGHVEMTEDQLIANVYLAV 186 5667777777776655.49******************764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (216 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1009 (0.0394989); expected 510.9 (0.02) Passed bias filter: 613 (0.0239969); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2184.97 // Query: FUN_000489-T1 [L=2707] Description: FUN_000489 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-102 335.3 26.4 7.1e-20 71.7 0.1 6.8 6 PDZ PDZ domain 4.7e-79 265.8 0.0 8e-79 265.0 0.0 1.4 1 Y_phosphatase Protein-tyrosine phosphatase 2.1e-49 165.5 16.9 2.5e-08 34.0 0.0 6.7 6 PDZ_6 PDZ domain 7.2e-37 126.0 5.6 9.1e-06 26.3 0.0 6.6 6 PDZ_2 PDZ domain 8.8e-28 97.5 3.5 2.6e-27 96.0 3.5 1.9 1 FERM_M FERM central domain 4.2e-18 66.1 1.1 4.2e-18 66.1 1.1 2.1 2 FERM_C FERM C-terminal PH-like domain 3.4e-13 49.7 0.1 1.1e-12 48.2 0.1 1.9 1 FERM_N FERM N-terminal domain 1.1e-06 29.6 0.0 2.9e-06 28.2 0.0 1.7 1 Tc-R-P Polymorphic toxin system, DSP-PTPase pho 1.2e-06 28.4 6.6 0.27 10.8 0.0 5.5 6 DUF6288 Family of unknown function (DUF6288) 1.9e-05 25.2 0.0 4.8e-05 23.9 0.0 1.7 1 PTP-SAK Swiss Army Knife protein, DSP-PTPase pho 1.9e-05 24.9 0.0 5.4e-05 23.5 0.0 1.7 1 DSPc Dual specificity phosphatase, catalytic 6.7e-05 23.3 0.0 6.7e-05 23.3 0.0 2.2 1 KIND Kinase non-catalytic C-lobe domain 0.00053 20.5 0.0 0.0014 19.1 0.0 1.6 1 Y_phosphatase3 Tyrosine phosphatase family 0.003 17.5 0.0 0.0068 16.3 0.0 1.5 1 PTP-NADK DSP-PTPase phosphatase fused to NAD+ Kin ------ inclusion threshold ------ 0.063 13.7 0.4 0.22 11.9 0.0 2.1 1 SNX17-27-31_F1_FERM Sortin nexin 17/27/31, FERM domain, F1 l 0.088 13.3 2.8 17 6.0 0.0 4.4 4 Pept_S41_N_bact Bacteroidetes, Peptidase, S41 family, N- 0.19 12.3 0.0 0.6 10.7 0.0 1.8 1 RA_2 RA like domain Domain annotation for each model (and alignments): >> PDZ PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.7 0.1 4.8e-23 7.1e-20 3 80 .. 1041 1121 .. 1039 1122 .. 0.95 2 ! 50.6 0.5 1.7e-16 2.6e-13 2 79 .. 1300 1379 .. 1299 1381 .. 0.94 3 ! 54.4 1.3 1.2e-17 1.8e-14 4 80 .. 1409 1488 .. 1406 1489 .. 0.92 4 ! 64.2 0.2 9.7e-21 1.5e-17 4 81 .] 1769 1844 .. 1765 1844 .. 0.92 5 ! 48.6 0.1 7.7e-16 1.2e-12 4 80 .. 1864 1938 .. 1862 1939 .. 0.87 6 ! 60.8 0.3 1.2e-19 1.8e-16 4 81 .] 2007 2086 .. 2005 2086 .. 0.95 Alignments for each domain: == domain 1 score: 71.7 bits; conditional E-value: 4.8e-23 PDZ 3 slekegrgglGfslkggsdks..dkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 ++ ke ++ lG+++ gg++++ d+gi+v++v +ggaa ++g LkaGDrIlsvNg+++e ++heeav lk+++++v L++ FUN_000489-T1 1041 KFTKEPGKLLGITVLGGENSKrlDRGIYVKSVTEGGAAWRDGrLKAGDRILSVNGVSLERVTHEEAVSILKNITSEVELKV 1121 667778999**********99**********************************************************98 PP == domain 2 score: 50.6 bits; conditional E-value: 1.7e-16 PDZ 2 vslekegrgglGfslkggsdks..dkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLt 79 v+lek + +lG+s++gg + s gi+v++++ +g+a+ +g + +GDrIl+vNg ++ ++h +av+ +k++ + +L+ FUN_000489-T1 1300 VDLEK-KDRSLGLSVSGGINTSvkLGGIYVKSLQLNGPADLDGrVAIGDRILAVNGISLIGVTHKQAVETIKMAPQRTRLV 1379 67888.99************99****************************************************9977775 PP == domain 3 score: 54.4 bits; conditional E-value: 1.2e-17 PDZ 4 lekegrgglGfslkggsdks...dkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 l k g gglG+sl+gg+ ++ + ++++ pg +a+a+g L++GD+Il+vNg d+ ++h ea++++++ ++v+L++ FUN_000489-T1 1409 LVK-GVGGLGLSLVGGKGAGeehGGFLRIKKMFPGQPAAASGkLQIGDIILQVNGNDMQGVTHQEAINLIRMGPQEVKLLV 1488 566.99*************9*8888889*******88888888************************************98 PP == domain 4 score: 64.2 bits; conditional E-value: 9.7e-21 PDZ 4 lekegrgglGfslkggsdksdkgifvsevlpggaaeaggLkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLtil 81 l + g gglGf+l gg d g+fv+e++ g+a e g L+ GD+Il+vN++d++++ h++av++l+ +k+ v+L++l FUN_000489-T1 1769 LVR-GSGGLGFTLLGGADTV-GGCFVKEIVDGPAKESGRLQSGDQILAVNDVDISSMKHMDAVDVLRATKQDVKLKVL 1844 455.99************97.**********99888888************************************985 PP == domain 5 score: 48.6 bits; conditional E-value: 7.7e-16 PDZ 4 lekegrgglGfslkggsdksdkgifvsevlpg.gaaeaggLkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLti 80 l + ++g++G+ +k+g+++ +i+v++v+p +aa +ggL+ GDrIl++Ng++v l a q l ++ + tL++ FUN_000489-T1 1864 LTRTTQGRIGLLIKEGDNQ---RIYVEDVVPEePAATQGGLRQGDRILEINGTKVDGLGFVAARQHLDAARPVATLLV 1938 56779**********9997...9*********66666666*****************999999999999887777776 PP == domain 6 score: 60.8 bits; conditional E-value: 1.2e-19 PDZ 4 lekegrgglGfslkggsdks..dkgifvsevlpggaaeagg.LkaGDrIlsvNgqdvenlsheeavqalkgskgkvtLtil 81 l+k g+ g+Gfsl+ + +gif++ ++pg+ ae +g Lk+GD+Il+vN++dv lsh +++ +l++ +g+v L+i+ FUN_000489-T1 2007 LNK-GPRGFGFSLVAAPTFNsnVQGIFIKTISPGSVAESDGrLKVGDQILKVNNEDVQGLSHAKVIGMLRKVTGTVELEIK 2086 666.99*********9999999********************************************************995 PP >> Y_phosphatase Protein-tyrosine phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 265.0 0.0 5.3e-82 8e-79 1 234 [] 2469 2699 .. 2469 2699 .. 0.95 Alignments for each domain: == domain 1 score: 265.0 bits; conditional E-value: 5.3e-82 Y_phosphatase 1 nkeknRykdvlpyDktrVklkkekgksdYInAsyikgyk.k.kkkyIatQgPlketvedFWrmvweekvevivmlteleekgrekceqYwpeee 92 nk+knR+++vlp++ktrVkl +++g++dYInA++ik + +yIatQgPl++t +dFW+mvwe++v vi+m+t+++e+g+ kc++Ywp e FUN_000489-T1 2469 NKNKNRFRNVLPFEKTRVKL-NREGSNDYINANHIKVPVgDdIYHYIATQGPLPNTTHDFWQMVWEQEVVVIAMITQEQEAGKVKCHRYWP--E 2559 899*****************.88888*********998853699***********************************************..6 PP Y_phosphatase 93 eesleygd.ikvtlkkekeeekeyvlrelelkkkkeeseerevkhlqyteWpdhgvPesaksllellekvrkskeeeegpivvhCsaGvgRtgt 185 e++l +++ ++v l++++ + +++ re+e+++ ++ + +++v h+++ +WpdhgvP+sa +l+e+++ +r + gp+vvhCsaG+gRtgt FUN_000489-T1 2560 EQPLVFERsFSVSLQRKE-DFGSFIEREFEISNIQSGD-TKTVFHINFITWPDHGVPKSAVELVEFVRFLRLLA-DGPGPVVVHCSAGIGRTGT 2650 6677776659*****666.999***************5.9*********************************9.89***************** PP Y_phosphatase 186 fiaidillqqleaeeevdileivkelrsqRpgmvqteeqylflyevvle 234 +i+id++l +e++ +vd+ +iv++lr+qR+gm+qt++qy+f+y+++le FUN_000489-T1 2651 LITIDAALGLMERDLSVDVNKIVRNLREQRQGMIQTKDQYIFCYNACLE 2699 **********************************************986 PP >> PDZ_6 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.0 0.0 1.7e-11 2.5e-08 1 52 [. 1068 1121 .. 1068 1122 .. 0.88 2 ! 23.8 0.2 2.6e-08 3.9e-05 2 54 .] 1328 1382 .. 1327 1382 .. 0.81 3 ! 30.5 0.1 2.1e-10 3.1e-07 7 54 .] 1441 1490 .. 1435 1490 .. 0.91 4 ! 29.3 0.1 5e-10 7.4e-07 6 54 .] 1796 1845 .. 1791 1845 .. 0.91 5 ! 24.9 0.2 1.2e-08 1.7e-05 2 54 .] 1886 1940 .. 1885 1940 .. 0.80 6 ! 30.7 0.1 1.8e-10 2.7e-07 1 54 [] 2032 2087 .. 2032 2087 .. 0.90 Alignments for each domain: == domain 1 score: 34.0 bits; conditional E-value: 1.7e-11 PDZ_6 1 vvtavvpgsPAerAG.lrvGDiIlsvNGepvrsle..dvarllqgaggesvrllv 52 +v++v +g+ A+r G l++GD+IlsvNG+++ +++ +++ +l+ + ++v+l+v FUN_000489-T1 1068 YVKSVTEGGAAWRDGrLKAGDRILSVNGVSLERVTheEAVSILK-NITSEVELKV 1121 599****************************5555479999999.8888888886 PP == domain 2 score: 23.8 bits; conditional E-value: 2.6e-08 PDZ_6 2 vtavvpgsPAerAG.lrvGDiIlsvNGepv..rsle..dvarllqgaggesvrllvrR 54 v++ + ++PA+ G + GD+Il+vNG+++ + ++++ ++ +++++rl++ R FUN_000489-T1 1328 VKSLQLNGPADLDGrVAIGDRILAVNGISLigV--ThkQAVETIK-MAPQRTRLVLDR 1382 7888999**********************8542..3358888888.888888887765 PP == domain 3 score: 30.5 bits; conditional E-value: 2.1e-10 PDZ_6 7 pgsPAerAG.lrvGDiIlsvNGepvrsle..dvarllqgaggesvrllvrR 54 pg PA+ G l+ GDiIl+vNG + + ++ +++ l++ g+++v llv+R FUN_000489-T1 1441 PGQPAAASGkLQIGDIILQVNGNDMQGVThqEAINLIR-MGPQEVKLLVKR 1490 9************************666667*******.**********98 PP == domain 4 score: 29.3 bits; conditional E-value: 5e-10 PDZ_6 6 vpgsPAerAG.lrvGDiIlsvNGepvrsle..dvarllqgaggesvrllvrR 54 v ++PA + G l+ GD Il+vN++++ s++ d++++l+ a+ + v l+v R FUN_000489-T1 1796 V-DGPAKESGrLQSGDQILAVNDVDISSMKhmDAVDVLR-ATKQDVKLKVLR 1845 4.6***********************999999*******.999999999987 PP == domain 5 score: 24.9 bits; conditional E-value: 1.2e-08 PDZ_6 2 vtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllqgaggesvrllvrR 54 v++vvp+ PA+ G lr GD+Il++NG++v +++ l+ a++ + +llv+R FUN_000489-T1 1886 VEDVVPEEPAATQGgLRQGDRILEINGTKVdgLGFVAARQHLD-AARPVATLLVER 1940 899999999999888***************6655557777777.666666666665 PP == domain 6 score: 30.7 bits; conditional E-value: 1.8e-10 PDZ_6 1 vvtavvpgsPAerAG.lrvGDiIlsvNGepv..rsledvarllqgaggesvrllvrR 54 +++++ pgs+Ae G l+vGD Il+vN+e+v s ++v+ +l+ v+l+++R FUN_000489-T1 2032 FIKTISPGSVAESDGrLKVGDQILKVNNEDVqgLSHAKVIGMLR-KVTGTVELEIKR 2087 58999**************************6666669999999.999999999987 PP >> PDZ_2 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.0 1.5e-08 2.3e-05 8 68 .. 1061 1122 .. 1049 1130 .. 0.86 2 ! 14.9 0.0 2.2e-05 0.033 4 48 .. 1316 1361 .. 1308 1377 .. 0.85 3 ! 14.2 0.0 3.6e-05 0.054 16 69 .. 1436 1490 .. 1414 1494 .. 0.71 4 ! 21.9 0.0 1.5e-07 0.00022 13 69 .. 1789 1845 .. 1774 1850 .. 0.85 5 ! 26.3 0.0 6.1e-09 9.1e-06 3 47 .. 1872 1918 .. 1870 1932 .. 0.86 6 ! 19.2 0.0 1e-06 0.0015 8 73 .. 2025 2091 .. 2013 2097 .. 0.88 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.5e-08 PDZ_2 8 edledgvvVvnVksssPaakag.lkagDvIlsidgkkvksltdleeallkkkpgdtvklqvl 68 + l++g++V +V++++ a + g lkagD+Ils++g +++ t+ e + k + ++v+l+v FUN_000489-T1 1061 KRLDRGIYVKSVTEGGAAWRDGrLKAGDRILSVNGVSLERVTHEEAVSILKNITSEVELKVS 1122 33455*************************************9999999999*****99985 PP == domain 2 score: 14.9 bits; conditional E-value: 2.2e-05 PDZ_2 4 GisfedledgvvVvnVksssPaakag.lkagDvIlsidgkkvkslt 48 Gi ++++ +g++V + + ++Pa+ g + +gD+Il+++g + t FUN_000489-T1 1316 GINTSVKLGGIYVKSLQLNGPADLDGrVAIGDRILAVNGISLIGVT 1361 677777778******************************8876555 PP == domain 3 score: 14.2 bits; conditional E-value: 3.6e-05 PDZ_2 16 VvnVksssPaakag.lkagDvIlsidgkkvksltdleeallkkkpgdtvklqvlR 69 + + +++Paa++g l++gD+Il+++g+ + t+ e l ++vkl v+R FUN_000489-T1 1436 IKKMFPGQPAAASGkLQIGDIILQVNGNDMQGVTHQEAINLIRMGPQEVKLLVKR 1490 55666789*********************99888755444433333566666666 PP == domain 4 score: 21.9 bits; conditional E-value: 1.5e-07 PDZ_2 13 gvvVvnVksssPaakag.lkagDvIlsidgkkvksltdleeallkkkpgdtvklqvlR 69 g V ++ ++ Pa+++g l+ gD+Il++++ ++s +++ + +++vkl+vlR FUN_000489-T1 1789 GCFVKEIVDG-PAKESGrLQSGDQILAVNDVDISSMKHMDAVDVLRATKQDVKLKVLR 1845 6666777766.****************************99999999999******99 PP == domain 5 score: 26.3 bits; conditional E-value: 6.1e-09 PDZ_2 3 lGisfedled.gvvVvnVksssPaakag.lkagDvIlsidgkkvksl 47 +G+ ++ ++ +++V +V ++ Paa +g l++gD+Il+i+g+kv+ l FUN_000489-T1 1872 IGLLIKEGDNqRIYVEDVVPEEPAATQGgLRQGDRILEINGTKVDGL 1918 666666655569*******************************9865 PP == domain 6 score: 19.2 bits; conditional E-value: 1e-06 PDZ_2 8 edledgvvVvnVksssPaakag.lkagDvIlsidgkkvksltdleeallkkkpgdtvklqvlRdgkt 73 ++ +g+ + + ++s a+ g lk+gD+Il+++++ v+ l++ + + k+ tv+l+++R +k FUN_000489-T1 2025 NSNVQGIFIKTISPGSVAESDGrLKVGDQILKVNNEDVQGLSHAKVIGMLRKVTGTVELEIKRPSKL 2091 455568999999999999999******************************************8876 PP >> FERM_M FERM central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.0 3.5 1.7e-30 2.6e-27 5 117 .] 658 769 .. 654 769 .. 0.96 Alignments for each domain: == domain 1 score: 96.0 bits; conditional E-value: 1.7e-30 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FERM_M 5 klqdevtrellYlQlkrdllegrlpcseeeallLAaLqlqaelgdyssesheseylslesflpkqllkklkskelekrvleahkklrglsaeeAkl 100 +l+ + t++++YlQl++d+l+g+l+c ee lL++L+lqae+gdy++ + ey+ ++++pk+++ k + +++ +++ + h++ +g++ eeA+l FUN_000489-T1 658 LLSYQKTFHQFYLQLRQDILNGQLYCHEEASYLLGGLALQAETGDYNDI-LADEYFLPQHYIPKRIIDKVSVDQVLQQLPQFHETFHGMTDEEAEL 752 667789****************************************977.9********************************************* PP xxxxxxxxxxxxxxxxx RF FERM_M 101 kylqiaqslptyGvelF 117 +++++aq+l++yGv+++ FUN_000489-T1 753 EFIKEAQKLQEYGVHFY 769 ****************8 PP >> FERM_C FERM C-terminal PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.1 6 9e+03 60 89 .. 644 673 .. 627 675 .. 0.70 2 ! 66.1 1.1 2.8e-21 4.2e-18 2 90 .. 786 873 .. 785 875 .. 0.95 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 6 FERM_C 60 tleFklessrackslwklcveqhkffrlrk 89 ++ F+++ + ++ +l++ h+f+ + + FUN_000489-T1 644 VVNFRVKFYVENVTLLSYQKTFHQFYLQLR 673 456777777777777777778888887765 PP == domain 2 score: 66.1 bits; conditional E-value: 2.8e-21 FERM_C 2 kegtellLGvsakGilvyekkdki..pknlFpWseirkisfkrkkfliklrkeedkkkeetleFklessrackslwklcveqhkffrlrks 90 ++++++++G++ +G++vye + ++ p+++++W+ ++k+sfk+kkf+i++r ++++ + ++F++++++++++l+++ + h+f +++k FUN_000489-T1 786 SDRETVWIGICIRGVTVYETRGSLkfPTHRHSWPLTKKLSFKKKKFFIEPR---ENPTASRMTFYTDHYKKARYLLQMSQAFHRFQMKMKT 873 57889*************99999999*************************...9999999************************999985 PP >> FERM_N FERM N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.2 0.1 7e-16 1.1e-12 1 63 [. 569 630 .. 569 631 .. 0.96 Alignments for each domain: == domain 1 score: 48.2 bits; conditional E-value: 7e-16 FERM_N 1 VrlLDgtklefevqkkatgqelLdqVckhlnlkEkdyFGLqfldsksehrWLdlekklekqak 63 V L+g++l++ v++ +t q l+dqV k+l+l+Ek +FGL+ +++ e ++Ldle kl+k+a+ FUN_000489-T1 569 VIVLNGQHLQIMVETTSTTQGLFDQVIKYLGLTEKCFFGLALEQDG-EQIFLDLEVKLAKYAP 630 5679******************************************.*************987 PP >> Tc-R-P Polymorphic toxin system, DSP-PTPase phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.0 1.9e-09 2.9e-06 53 98 .. 2607 2653 .. 2583 2658 .. 0.82 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.9e-09 Tc-R-P 53 pikDlsaP.sekqveeivrlidalldndkgvvvHCraGvGRtGtvlA 98 + +D P s ++ e+vr+++ l d ++vvvHC aG+GRtGt++ FUN_000489-T1 2607 TWPDHGVPkSAVELVEFVRFLRLLADGPGPVVVHCSAGIGRTGTLIT 2653 4566666634557889****************************985 PP >> DUF6288 Family of unknown function (DUF6288) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.9 0.0 0.0027 4.1 3 47 .. 1067 1113 .. 1065 1128 .. 0.80 2 ? 1.4 0.1 0.13 1.9e+02 3 32 .. 1326 1357 .. 1325 1373 .. 0.87 3 ! 10.8 0.0 0.00018 0.27 3 35 .. 1434 1468 .. 1433 1479 .. 0.85 4 ? -1.8 0.0 1.2 1.8e+03 12 34 .. 1798 1822 .. 1792 1841 .. 0.82 5 ? 2.8 0.0 0.051 76 2 33 .. 1883 1916 .. 1882 1932 .. 0.83 6 ? 4.4 0.0 0.016 24 3 36 .. 2031 2066 .. 2029 2103 .. 0.80 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0027 DUF6288 3 ikvtkveegSPAd..Gklkvgdvilgvngktlkkfskdprialanai 47 i v++v eg A G lk gd il+vng++l++++ + +++ + i FUN_000489-T1 1067 IYVKSVTEGGAAWrdGRLKAGDRILSVNGVSLERVTHEEAVSILKNI 1113 88999****999556***************99977766655554444 PP == domain 2 score: 1.4 bits; conditional E-value: 0.13 DUF6288 3 ikvtkveegSPAd..Gklkvgdvilgvngktl 32 i v++++ + PAd G ++ gd il+vng +l FUN_000489-T1 1326 IYVKSLQLNGPADldGRVAIGDRILAVNGISL 1357 678999999***999**************855 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00018 DUF6288 3 ikvtkveegSPAd..Gklkvgdvilgvngktlkkf 35 ++++k+ g PA+ Gkl+ gd+il vng+ ++ + FUN_000489-T1 1434 LRIKKMFPGQPAAasGKLQIGDIILQVNGNDMQGV 1468 68999******9999***************88844 PP == domain 4 score: -1.8 bits; conditional E-value: 1.2 DUF6288 12 SPAd..Gklkvgdvilgvngktlkk 34 PA+ G l+ gd il+vn + +++ FUN_000489-T1 1798 GPAKesGRLQSGDQILAVNDVDISS 1822 599889*************997764 PP == domain 5 score: 2.8 bits; conditional E-value: 0.051 DUF6288 2 qikvtkveegSPAd..Gklkvgdvilgvngktlk 33 i v+ v + PA+ G l+ gd il +ng++++ FUN_000489-T1 1883 RIYVEDVVPEEPAAtqGGLRQGDRILEINGTKVD 1916 588999*******999***************765 PP == domain 6 score: 4.4 bits; conditional E-value: 0.016 DUF6288 3 ikvtkveegSPAd..Gklkvgdvilgvngktlkkfs 36 i ++++ gS A+ G lkvgd il vn + ++ +s FUN_000489-T1 2031 IFIKTISPGSVAEsdGRLKVGDQILKVNNEDVQGLS 2066 679999****99889**************9887443 PP >> PTP-SAK Swiss Army Knife protein, DSP-PTPase phosphatase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 3.2e-08 4.8e-05 76 149 .. 2626 2689 .. 2604 2693 .. 0.83 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 3.2e-08 PTP-SAK 76 llasllkrdeektpvlvHCgGGkGRaGTvlacyLvafGfkppaaedkeqpalsakeaisllralrpgsieteaq 149 +l+ l+ d+ pv+vHC +G GR+GT++ + +a G++++ +++ ++ ++ lr++r+g i+t+ q FUN_000489-T1 2626 FLRLLA--DGP-GPVVVHCSAGIGRTGTLITID-AALGLMERDL------SVDVNKIVRNLREQRQGMIQTKDQ 2689 444442..444.58***************9976.6669999999......5799*****************988 PP >> DSPc Dual specificity phosphatase, catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 3.6e-08 5.4e-05 50 122 .. 2611 2689 .. 2568 2694 .. 0.74 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 3.6e-08 DSPc 50 etetkiskyleeavefiekakqkgkkvlVHCqaGisRSatlii...a.Ylmktk.nlslneayeflkerr.saispnan 122 + k + +l e v+f++ +++ + v+VHC aGi R++tli+ a lm+++ ++++n+ ++ l+e+r ++i +++ FUN_000489-T1 2611 HGVPKSAVELVEFVRFLRLLADGPGPVVVHCSAGIGRTGTLITidaAlGLMERDlSVDVNKIVRNLREQRqGMIQTKDQ 2689 4455666788899999999999*******************96332324777652569999999999999455555555 PP >> KIND Kinase non-catalytic C-lobe domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 4.4e-08 6.7e-05 1 119 [. 9 147 .. 9 156 .. 0.83 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 4.4e-08 KIND 1 lsLeeiLklyeqpineEqAWAvCyqccrglaeaerrrk....ekvrrikeasdvllkrDGavkleseaeedke................lksavse 76 ++LeeiL++ p++e++ WA+ q ++ l++ + k + +++++l +G+vk + ++ ++++ ++ + e FUN_000489-T1 9 VTLEEILEVRAGPLREDELWALLLQSSEALHDVLVKGKarrkGLLTYTVTPESLRLCYNGKVKFSLHTVSSRNrsftapeiyskrakpiGNEGTLE 104 68**************************9987654433222233344557899*********9877766555556999******998876677888 PP KIND 77 eeviesLGvviykALDyGlkenEErelspdLErLidlmtnsee 119 + i sLG+ +y+A +y + + +ls LE ++ +m + ++ FUN_000489-T1 105 KIFIYSLGMTLYHAAEYEIPVEKPVNLSVSLEGVLLSMCEESA 147 999******************************9999988765 PP >> Y_phosphatase3 Tyrosine phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 9.3e-07 0.0014 117 157 .. 2622 2662 .. 2608 2691 .. 0.81 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 9.3e-07 Y_phosphatase3 117 ayravlealad.eepvlfHCtaGKDRTGvaaalllsllGvde 157 ++ ++l+ lad ++pv++HC+aG RTG ++ + ++lG e FUN_000489-T1 2622 EFVRFLRLLADgPGPVVVHCSAGIGRTGTLIT-IDAALGLME 2662 68899******555**************9864.455556555 PP >> PTP-NADK DSP-PTPase phosphatase fused to NAD+ Kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 4.5e-06 0.0068 96 156 .. 2624 2685 .. 2593 2691 .. 0.75 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 4.5e-06 PTP-NADK 96 erfaelvsdsekrplyvhskeGvgRtsamvsrwrqy..vsrgesveealakesleakdkgsle 156 rf++l++d p+ vh+ +G+gRt+++++ ++r sv+ + ++l+ + +g ++ FUN_000489-T1 2624 VRFLRLLAD-GPGPVVVHCSAGIGRTGTLITIDAALglMERDLSVDVNKIVRNLREQRQGMIQ 2685 378888888.6789***************9754432337777777776666666666666555 PP >> SNX17-27-31_F1_FERM Sortin nexin 17/27/31, FERM domain, F1 lobe # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.00015 0.22 4 63 .. 568 625 .. 566 643 .. 0.85 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00015 SNX17-27-31_F1_FERM 4 dvylmngkkikvkvsstdqtedvLekvakkielpeelvkYFgLFlvkkeeegklsvvrkL 63 v+++ng+++++ v++t++t+ + +v+k ++l+e+ ++FgL l ++ e+ l + kL FUN_000489-T1 568 TVIVLNGQHLQIMVETTSTTQGLFDQVIKYLGLTEK--CFFGLALEQDGEQIFLDLEVKL 625 6999*******************************8..5899999888776555555555 PP >> Pept_S41_N_bact Bacteroidetes, Peptidase, S41 family, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.066 1e+02 20 33 .. 1084 1097 .. 1069 1107 .. 0.86 2 ? -1.7 0.1 2.7 4.1e+03 22 32 .. 1345 1355 .. 1339 1361 .. 0.83 3 ? -1.3 0.1 2.1 3.2e+03 20 36 .. 1806 1822 .. 1800 1831 .. 0.83 4 ? 6.0 0.0 0.011 17 14 34 .. 1895 1915 .. 1882 1925 .. 0.87 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.066 Pept_S41_N_bact 20 lrdkDrivavdGkp 33 l+++Dri++v+G+ FUN_000489-T1 1084 LKAGDRILSVNGVS 1097 89**********86 PP == domain 2 score: -1.7 bits; conditional E-value: 2.7 Pept_S41_N_bact 22 dkDrivavdGk 32 +Dri+av+G FUN_000489-T1 1345 IGDRILAVNGI 1355 58********6 PP == domain 3 score: -1.3 bits; conditional E-value: 2.1 Pept_S41_N_bact 20 lrdkDrivavdGkpask 36 l+ +D+i+av+ +++s FUN_000489-T1 1806 LQSGDQILAVNDVDISS 1822 899********998765 PP == domain 4 score: 6.0 bits; conditional E-value: 0.011 Pept_S41_N_bact 14 sllkaglrdkDrivavdGkpa 34 ++++ glr++Dri+ ++G ++ FUN_000489-T1 1895 AATQGGLRQGDRILEINGTKV 1915 57889*************986 PP >> RA_2 RA like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.0004 0.6 5 46 .. 567 608 .. 564 620 .. 0.89 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.0004 RA_2 5 vkvflmDgsskavevdsattarevceklaeklglkdsegFsL 46 v+v+ +g+ +++v++++t++ + +++++ lgl+++ F+L FUN_000489-T1 567 VTVIVLNGQHLQIMVETTSTTQGLFDQVIKYLGLTEKCFFGL 608 899*********************************955665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2707 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1030 (0.040321); expected 510.9 (0.02) Passed bias filter: 647 (0.0253279); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.72u 0.39s 00:00:01.10 Elapsed: 00:00:00.43 # Mc/sec: 25332.20 // Query: FUN_000490-T1 [L=157] Description: FUN_000490 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 530 (0.0207477); expected 510.9 (0.02) Passed bias filter: 423 (0.016559); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.34s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1630.37 // Query: FUN_000491-T1 [L=348] Description: FUN_000491 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-11 43.7 0.0 2e-05 24.9 0.0 2.4 2 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc- 1.2e-05 25.7 0.0 0.00067 20.0 0.0 2.5 2 MafB19-deam MafB19-like deaminase 0.0062 17.0 0.0 0.014 15.9 0.0 1.6 1 Bd3614-deam Bd3614-like deaminase Domain annotation for each model (and alignments): >> dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.0 2.3e-09 2e-05 25 100 .. 42 107 .. 25 109 .. 0.84 2 ! 16.5 0.0 9.6e-07 0.0082 14 49 .. 272 306 .. 257 330 .. 0.78 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 2.3e-09 dCMP_cyt_deam_1 25 pvGavivkkdgeiiatGyngenagndptaHAEvnairkavkeggvklegatlyvtlePCgmCaqaiiesgikkvvv 100 +vGav+v ++i+++ + + aHA i++ + eg+ ++v+ PC+ C+++++++++++v++ FUN_000491-T1 42 KVGAVLVLP--NDISYAIDCSR----DGAHAVARLIMAHPNI---P-EGCKVFVSRKPCSLCTKLLVQAKVERVFY 107 899999994..68999988873....3579999999888743...3.68*************************98 PP == domain 2 score: 16.5 bits; conditional E-value: 9.6e-07 dCMP_cyt_deam_1 14 aakkay.kkskfpvGavivkkdgeiiatGyngenagn 49 +a+ + +++k+ vGavi+ +++ei++ G+ng +++ FUN_000491-T1 272 LAE--RtDDPKTGVGAVILSEKKEIVGLGWNGFPKKA 306 333..3499**********************988765 PP >> MafB19-deam MafB19-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 7.9e-08 0.00067 74 105 .. 78 109 .. 60 149 .. 0.76 2 ? 3.0 0.0 0.015 1.2e+02 14 41 .. 272 300 .. 260 326 .. 0.77 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 7.9e-08 MafB19-deam 74 lddatlYVtrepCsmCagaiiqaglkslvyga 105 ++++ ++V r+pCs C ++++qa+++++ y FUN_000491-T1 78 PEGCKVFVSRKPCSLCTKLLVQAKVERVFYLP 109 78999**********************99864 PP == domain 2 score: 3.0 bits; conditional E-value: 0.015 MafB19-deam 14 veeaidadevkigavvv.kdkkvigvnsn 41 + e++d + +gav+ ++k+++g++ n FUN_000491-T1 272 LAERTDDPKTGVGAVILsEKKEIVGLGWN 300 56788899999***988799******999 PP >> Bd3614-deam Bd3614-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 1.6e-06 0.014 52 91 .. 75 110 .. 47 133 .. 0.79 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 1.6e-06 Bd3614-deam 52 rpleagarllvtlqcCkmCAalvvaaaddpgrlkvvYlee 91 +++g +++v+ ++C +C l+v+a + +v Yl FUN_000491-T1 75 PNIPEGCKVFVSRKPCSLCTKLLVQAKV----ERVFYLPI 110 579********************99988....55666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (348 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 829 (0.0324525); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3425.57 // Query: FUN_000492-T1 [L=96] Description: FUN_000492 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.025 15.1 2.0 0.05 14.1 2.0 1.6 1 Sin3_corepress Sin3 family co-repressor Domain annotation for each model (and alignments): >> Sin3_corepress Sin3 family co-repressor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 2.0 1.9e-06 0.05 9 92 .. 10 90 .. 6 96 .] 0.69 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.9e-06 Sin3_corepress 9 lLpkseqklkcsgrdelckevLNdewvsvptwasedsgsfvahrknqyeealfrvEder.yeldlliesnkrtiklleklaekie 92 +++k++++ + + rde ++e L + w p+w+s d++ ++ +r ++lf+ e ++++++++k i+l++k++++ + FUN_000492-T1 10 AMQKNYKSSEKERRDEKKNELLENYWKQDPQWQSFDDS-MNEKR---GPQKLFEHAREFpKLIEFCLSTCKLSIRLIQKFYAQKQ 90 68999*****************************9994.44333...23334433333203356666666666666666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (96 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2026 (0.079311); expected 510.9 (0.02) Passed bias filter: 713 (0.0279115); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 971.01 // Query: FUN_000493-T1 [L=429] Description: FUN_000493 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-16 58.1 0.0 3.3e-09 37.0 0.0 2.6 2 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc- 4.2e-08 33.6 0.0 0.0055 17.1 0.0 2.4 2 MafB19-deam MafB19-like deaminase Domain annotation for each model (and alignments): >> dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 1.8e-07 0.0022 25 99 .. 40 104 .. 30 106 .. 0.84 2 ! 37.0 0.0 2.6e-13 3.3e-09 4 101 .. 262 375 .. 259 376 .. 0.93 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.8e-07 dCMP_cyt_deam_1 25 pvGavivkkdgeiiatGyngenagndptaHAEvnairkavkeggvklegatlyvtlePCgmCaqaiiesgikkvv 99 +vGav+v ++i ++ + + +HA i+ kl+g+ ++v+ PC+ C++++++ ++++v+ FUN_000493-T1 40 KVGAVLVLP--NDICYAIDWSR----DGVHAVARLIMRHP----DKLKGSKFFVSRKPCSFCTKLLVQKEVQRVF 104 689999994..58888888774....34689888888876....58999**********************9996 PP == domain 2 score: 37.0 bits; conditional E-value: 2.6e-13 dCMP_cyt_deam_1 4 deklmrlalkaakkaykkskfpvGavivkkdgeiiatGyngenagnd....................ptaHAEvnairkavkeggvklegatly 77 +m la+ +a++ +++++ vGavi++k+ eii+ G+ng +++ +++ AE+na+++ +++++g tl+ FUN_000493-T1 262 AYHFMILAKFLAERT-DDPRTGVGAVIIDKNMEIIGLGWNGFPRKARygefsrasytdtkvqdkkypYIIYAEQNALMMRN---TQNVDGGTLF 351 557899999999999.***************************9999******************************9887...458899**** PP dCMP_cyt_deam_1 78 vtlePCgmCaqaiiesgikkvvvg 101 +t +P + ++++ gik++v+g FUN_000493-T1 352 MTKTPSDESTALLKMQGIKTIVLG 375 *********************986 PP >> MafB19-deam MafB19-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.0 3.9e-06 0.049 73 105 .. 75 107 .. 58 143 .. 0.70 2 ! 17.1 0.0 4.3e-07 0.0055 6 114 .. 264 382 .. 258 395 .. 0.76 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 3.9e-06 MafB19-deam 73 klddatlYVtrepCsmCagaiiqaglkslvyga 105 kl++ +V r+pCs C ++++q ++++ FUN_000493-T1 75 KLKGSKFFVSRKPCSFCTKLLVQKEVQRVFNLP 107 5677789*******************9997654 PP == domain 2 score: 17.1 bits; conditional E-value: 4.3e-07 MafB19-deam 6 afrkalelveeaidadevkigavvv.kdkkvigvnsn.............dkvtekelkakateHaEilalqrAtkklakkklddatlYVtrepCs 87 f+ +++ + e++d +gav++ k+ ++ig++ n t+++++ k i+a q A ++ ++d+ tl+ t+ p + FUN_000493-T1 264 HFMILAKFLAERTDDPRTGVGAVIIdKNMEIIGLGWNgfprkarygefsrASYTDTKVQDKKYP-YIIYAEQNALMMRNTQNVDGGTLFMTKTPSD 358 35666777899999999********9999*************9999997633333333222221.223555555556678889************* PP MafB19-deam 88 mCagaiiqaglkslvygagdlkglekl 114 ++ g+k++v g + ++e+ FUN_000493-T1 359 ESTALLKMQGIKTIVLGEE---FIEEA 382 **999999*******9988...65554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (429 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 969 (0.0379331); expected 510.9 (0.02) Passed bias filter: 557 (0.0218047); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4256.68 // Query: FUN_000494-T1 [L=475] Description: FUN_000494 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-24 85.4 0.2 3.4e-16 59.5 0.0 2.4 2 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc- 3.1e-13 50.2 0.1 2.5e-06 27.9 0.0 2.4 2 MafB19-deam MafB19-like deaminase 1e-05 26.0 0.1 0.058 13.9 0.1 2.4 2 Bd3614-deam Bd3614-like deaminase ------ inclusion threshold ------ 0.015 15.8 1.0 1.4 9.4 0.0 2.6 3 APOBEC_N APOBEC-like N-terminal domain 0.036 14.5 0.1 4.7 7.7 0.0 3.0 3 AID Activation induced deaminase 0.07 13.6 0.0 0.17 12.3 0.0 1.7 2 Ig-CFAP74_3rd CFAP74 third Ig-like domain 0.098 13.2 0.2 8.2 7.0 0.0 2.4 2 SNAD4 Secreted Novel AID/APOBEC-like Deaminase 4 Domain annotation for each model (and alignments): >> dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.1 1.4e-08 5e-05 24 100 .. 76 142 .. 62 144 .. 0.81 2 ! 59.5 0.0 9.4e-20 3.4e-16 2 101 .. 296 411 .. 295 412 .. 0.95 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 1.4e-08 dCMP_cyt_deam_1 24 fpvGavivkkdgeiiatGyngenagndptaHAEvnairkavkeggvklegatlyvtlePCgmCaqaiiesgikkvvv 100 +vGav+v ++++++ + + + +HA i++ + e++ ++v+ PC+ C+++++++++++v++ FUN_000494-T1 76 KKVGAVLVLP--NEMSYAIDCSR----NGVHAVARLIMAHPNI---P-EDCKVFVSRKPCSFCTKLMVQAKVERVFY 142 5899999995..57777777763....4579999999888733...3.69*************************98 PP == domain 2 score: 59.5 bits; conditional E-value: 9.4e-20 dCMP_cyt_deam_1 2 ekdeklmrlalkaakkaykkskfpvGavivkkdgeiiatGyngenagnd....................ptaHAEvnairkavkeggvklegat 75 e+ + lm+la+ +a + +++ + vGaviv+++ ei++ G+ng +++ +++HAE+na+++ ++++eg t FUN_000494-T1 296 EQANHLMTLAKFLAMRT-DDPTTGVGAVIVNEKMEIVGLGWNGFPKKARygefarashkdegvqdkkypYIIHAEQNALMMRN---TKNVEGGT 385 677899*********99.**************************99999******************************9887...45899*** PP dCMP_cyt_deam_1 76 lyvtlePCgmCaqaiiesgikkvvvg 101 l+vt +PC +C+ ++ +i +vv+g FUN_000494-T1 386 LFVTKTPCDECTPLLEMQKITTVVLG 411 ***********************987 PP >> MafB19-deam MafB19-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 1.9e-07 0.00068 69 104 .. 109 143 .. 91 163 .. 0.81 2 ! 27.9 0.0 6.8e-10 2.5e-06 9 112 .. 303 423 .. 292 444 .. 0.77 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 1.9e-07 MafB19-deam 69 lakkklddatlYVtrepCsmCagaiiqaglkslvyg 104 ++ ++d+ ++V r+pCs C ++++qa+++++ y FUN_000494-T1 109 HPNI-PEDCKVFVSRKPCSFCTKLMVQAKVERVFYL 143 4444.89*************************9885 PP == domain 2 score: 27.9 bits; conditional E-value: 6.8e-10 MafB19-deam 9 kalelveeaidadevkigavvv.kdkkvigvnsn.................dkvtekelkakateHaEilalqrAtkklakkklddatlYVtrepC 86 +++ + ++d +gav+v ++ +++g++ n d+ + ++ k HaE +al+ ++k++++ tl+Vt+ pC FUN_000494-T1 303 TLAKFLAMRTDDPTTGVGAVIVnEKMEIVGLGWNgfpkkarygefarashkDE-GVQDKKYPYIIHAEQNALMMR----NTKNVEGGTLFVTKTPC 393 44555666777888889*****8999*************99999987766422.223334556679999998865....55557889********* PP MafB19-deam 87 smCagaiiqaglkslvygagdlkg....le 112 + C ++ ++ ++v g + ++g ++ FUN_000494-T1 394 DECTPLLEMQKITTVVLGEKIEDGakqgIS 423 ****************99988877555554 PP >> Bd3614-deam Bd3614-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.1 1.6e-05 0.058 51 85 .. 109 139 .. 76 150 .. 0.80 2 ! 9.7 0.0 0.00032 1.2 34 73 .. 365 399 .. 353 413 .. 0.82 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.6e-05 Bd3614-deam 51 rrpleagarllvtlqcCkmCAalvvaaaddpgrlk 85 ++++ +++v+ ++C C l+v+a ++ + FUN_000494-T1 109 HPNIPEDCKVFVSRKPCSFCTKLMVQAKVE----R 139 3679*******************9999874....3 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00032 Bd3614-deam 34 vLHAevnLlapllreearrpleagarllvtlqcCkmCAal 73 ++HAe n l+ ++++ + +g +l+vt +C C l FUN_000494-T1 365 IIHAEQNALMMRNTKN----V-EGGTLFVTKTPCDECTPL 399 68****9888665555....5.5778***********866 PP >> APOBEC_N APOBEC-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.017 61 68 87 .. 115 134 .. 93 140 .. 0.82 2 ? 9.4 0.0 0.00038 1.4 33 84 .. 352 399 .. 342 409 .. 0.76 3 ? -3.5 0.0 3.6 1.3e+04 9 30 .. 428 449 .. 423 458 .. 0.71 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.017 APOBEC_N 68 evtlyvswSPCveCaeelak 87 ++vs PC C + +++ FUN_000494-T1 115 DCKVFVSRKPCSFCTKLMVQ 134 5689************9987 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00038 APOBEC_N 33 slkkGvlrnek.a.elHaEeaflealsdlvlepselyevtlyvswSPCveCaee 84 ++++Gv +++k +HaE+ l + ++++ tl+v++ PC eC FUN_000494-T1 352 HKDEGV-QDKKyPyIIHAEQNALMM-----RNTKNVEGGTLFVTKTPCDECTPL 399 556777.666642479999998884.....567778888************865 PP == domain 3 score: -3.5 bits; conditional E-value: 3.6 APOBEC_N 9 ryaegrnktflcyevkreekss 30 + + ++ + f+c+ +k + ++s FUN_000494-T1 428 HEGVHKDRNFTCFSMKSNVDGS 449 5556777788999998876655 PP >> AID Activation induced deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.039 1.4e+02 6 39 .. 100 133 .. 96 150 .. 0.74 2 ? -1.1 0.0 0.73 2.7e+03 40 59 .. 176 195 .. 164 202 .. 0.77 3 ? 7.7 0.0 0.0013 4.7 6 36 .. 362 398 .. 357 405 .. 0.66 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.039 AID 6 haeikfikdnkipseitelwikksPchecsekll 39 ha+ i + e ++++ + Pc+ c++ ++ FUN_000494-T1 100 HAVARLIMAHPNIPEDCKVFVSRKPCSFCTKLMV 133 56666666666666778999*********98765 PP == domain 2 score: -1.1 bits; conditional E-value: 0.73 AID 40 khfkslplkptlfiGriars 59 ++fk +p+ t+f+ +++ FUN_000494-T1 176 NLFKVSPIGQTIFVPDVSKD 195 68999********9988875 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0013 AID 6 haeikfikdnkipseit......elwikksPchecse 36 ++ i + n + ++t +l+++k+Pc ec+ FUN_000494-T1 362 YPYIIHAEQNALMMRNTknveggTLFVTKTPCDECTP 398 555555555555555543333338***********85 PP >> Ig-CFAP74_3rd CFAP74 third Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 4.2 1.5e+04 69 96 .. 107 134 .. 105 138 .. 0.75 2 ? 12.3 0.0 4.7e-05 0.17 36 101 .. 203 268 .. 168 276 .. 0.86 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 4.2 Ig-CFAP74_3rd 69 lprkslaedakkffdketgvlevpltik 96 +++ +++ed+k f+ ++ + + l+++ FUN_000494-T1 107 MAHPNIPEDCKVFVSRKPCSFCTKLMVQ 134 5677888888888888888887777776 PP == domain 2 score: 12.3 bits; conditional E-value: 4.7e-05 Ig-CFAP74_3rd 36 kfevckelkkhleilPktgyiqakssFsaqlkflprkslaeda.kkffdketgvlevpltikvadqt 101 +fe ++ +++++e + k+ y + s+Fsa+ k lp sl e+ k++ d+ ++++e t va+q+ FUN_000494-T1 203 RFESPEAIRSYMEGVLKKKYWDPLSTFSAK-KDLPWPSLDETMkKEVKDQFKNMMEWMATFCVAQQK 268 699999***********************9.889******997256778889999999999999885 PP >> SNAD4 Secreted Novel AID/APOBEC-like Deaminase 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.1 0.023 85 55 74 .. 116 135 .. 101 141 .. 0.81 2 ? 7.0 0.0 0.0022 8.2 33 69 .. 367 398 .. 346 407 .. 0.69 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.023 SNAD4 55 itwylswsPCaeCaekiaef 74 +++s PC+ C++ +++ FUN_000494-T1 116 CKVFVSRKPCSFCTKLMVQA 135 5679**********998875 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0022 SNAD4 33 HaEilflekiksreldksksysitwylswsPCaeCae 69 HaE + l + + +++ t++++ +PC eC+ FUN_000494-T1 367 HAEQNALMMRNTKNV-----EGGTLFVTKTPCDECTP 398 777776666555222.....3459***********75 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (475 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 745 (0.0291642); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 4828.09 // Query: FUN_000495-T1 [L=295] Description: FUN_000495 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 736 (0.0288119); expected 510.9 (0.02) Passed bias filter: 409 (0.016011); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2882.52 // Query: FUN_000496-T1 [L=418] Description: FUN_000496 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-23 80.9 0.3 2.6e-16 59.8 0.0 2.5 2 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc- 2.4e-13 50.6 0.2 1.6e-06 28.5 0.1 2.2 2 MafB19-deam MafB19-like deaminase 2e-05 25.0 0.1 0.13 12.8 0.0 2.3 2 Bd3614-deam Bd3614-like deaminase 0.0033 17.8 0.1 3.9 7.9 0.0 3.1 3 AID Activation induced deaminase 0.0066 17.0 0.2 1.1 9.7 0.0 2.5 2 APOBEC_N APOBEC-like N-terminal domain ------ inclusion threshold ------ 0.068 13.7 0.3 6.9 7.2 0.0 2.3 2 SNAD4 Secreted Novel AID/APOBEC-like Deaminase 4 Domain annotation for each model (and alignments): >> dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.1 3.6e-07 0.0015 61 100 .. 67 106 .. 40 108 .. 0.75 2 ! 59.8 0.0 6.2e-20 2.6e-16 2 101 .. 257 372 .. 256 373 .. 0.94 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 3.6e-07 dCMP_cyt_deam_1 61 rkavke.ggvklegatlyvtlePCgmCaqaiiesgikkvvv 100 + + + ++ e++ ++v+ PC+ C++++++++++kv++ FUN_000496-T1 67 ARLMMAhPNIP-ENCKVFVSRKPCSFCTKLLVQAKVEKVFY 106 33333312333.68*************************98 PP == domain 2 score: 59.8 bits; conditional E-value: 6.2e-20 dCMP_cyt_deam_1 2 ekdeklmrlalkaakkaykkskfpvGavivkkdgeiiatGyngenagnd....................ptaHAEvnairkavkeggvklegat 75 ++ + lm+la+ +a + +++ + vGaviv+++ ei++ G+ng +++ +++HAE+na+++ ++++eg t FUN_000496-T1 257 KQANHLMTLAKILAMRT-DDPTTGVGAVIVNEKMEIVGLGWNGFPKKARygefarashkdegvqdkkypYIIHAEQNALMMRN---TKNVEGGT 346 567889*********99.**************************99999******************************9887...45899*** PP dCMP_cyt_deam_1 76 lyvtlePCgmCaqaiiesgikkvvvg 101 l+vt +PC +C+ ++ +i +vv+g FUN_000496-T1 347 LFVTKTPCDECTPLLEMQKITTVVLG 372 ***********************987 PP >> MafB19-deam MafB19-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 1.7e-07 0.00071 62 104 .. 66 107 .. 55 129 .. 0.81 2 ! 28.5 0.1 3.7e-10 1.6e-06 8 115 .. 263 387 .. 256 412 .. 0.77 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 1.7e-07 MafB19-deam 62 lqrAtkklakkklddatlYVtrepCsmCagaiiqaglkslvyg 104 + r + + ++ ++++ ++V r+pCs C ++++qa+++++ y FUN_000496-T1 66 VARLMMAHPNI-PENCKVFVSRKPCSFCTKLLVQAKVEKVFYL 107 55554444444.899************************9985 PP == domain 2 score: 28.5 bits; conditional E-value: 3.7e-10 MafB19-deam 8 rkalelveeaidadevkigavvv.kdkkvigvnsn.................dkvtekelkakateHaEilalqrAtkklakkklddatlYVtrep 85 + +++ + ++d +gav+v ++ +++g++ n d+ + ++ k HaE +al+ ++k++++ tl+Vt+ p FUN_000496-T1 263 MTLAKILAMRTDDPTTGVGAVIVnEKMEIVGLGWNgfpkkarygefarashkDE-GVQDKKYPYIIHAEQNALMMR----NTKNVEGGTLFVTKTP 353 44555667778888889******8999***************999987766422.223334556679999998865....55557889******** PP MafB19-deam 86 CsmCagaiiqaglkslvygagdlkg....leklk 115 C+ C ++ ++ ++v g + ++g ++ k FUN_000496-T1 354 CDECTPLLEMQKITTVVLGEKIEDGakqgISYTK 387 *****************99998887555555555 PP >> Bd3614-deam Bd3614-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.0 3e-05 0.13 45 87 .. 69 105 .. 37 114 .. 0.77 2 ! 9.9 0.0 0.00023 0.98 34 73 .. 326 360 .. 314 374 .. 0.82 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3e-05 Bd3614-deam 45 llreearrpleagarllvtlqcCkmCAalvvaaaddpgrlkvv 87 l +++ ++++ +++v+ ++C C l+v+a + kv FUN_000496-T1 69 LMMAH--PNIPENCKVFVSRKPCSFCTKLLVQAKV----EKVF 105 44443..689*******************999887....4455 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00023 Bd3614-deam 34 vLHAevnLlapllreearrpleagarllvtlqcCkmCAal 73 ++HAe n l+ ++++ + +g +l+vt +C C l FUN_000496-T1 326 IIHAEQNALMMRNTKN----V-EGGTLFVTKTPCDECTPL 360 68*****888665555....5.5778***********866 PP >> AID Activation induced deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.7 0.0 0.0046 20 5 40 .. 63 98 .. 59 114 .. 0.78 2 ? -0.3 0.0 0.35 1.5e+03 40 60 .. 140 160 .. 127 168 .. 0.78 3 ! 7.9 0.0 0.00093 3.9 6 36 .. 323 359 .. 318 366 .. 0.66 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0046 AID 5 ihaeikfikdnkipseitelwikksPchecsekllk 40 +ha+ + + e+ ++++ + Pc+ c++ l++ FUN_000496-T1 63 VHAVARLMMAHPNIPENCKVFVSRKPCSFCTKLLVQ 98 6666666666676678899************98875 PP == domain 2 score: -0.3 bits; conditional E-value: 0.35 AID 40 khfkslplkptlfiGriarsf 60 ++fk +p+ t+f+ +++ FUN_000496-T1 140 NLFKVSPIGQTIFVPDVPKAV 160 6899*********99998865 PP == domain 3 score: 7.9 bits; conditional E-value: 0.00093 AID 6 haeikfikdnkipseit......elwikksPchecse 36 ++ i + n + ++t +l+++k+Pc ec+ FUN_000496-T1 323 YPYIIHAEQNALMMRNTknveggTLFVTKTPCDECTP 359 555555555555555543333338***********85 PP >> APOBEC_N APOBEC-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.1 0.01 44 64 87 .. 75 98 .. 50 104 .. 0.81 2 ! 9.7 0.0 0.00026 1.1 33 84 .. 313 360 .. 303 371 .. 0.76 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.01 APOBEC_N 64 selyevtlyvswSPCveCaeelak 87 + + ++vs PC C + l++ FUN_000496-T1 75 NIPENCKVFVSRKPCSFCTKLLVQ 98 55567789***********99987 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00026 APOBEC_N 33 slkkGvlrnek.a.elHaEeaflealsdlvlepselyevtlyvswSPCveCaee 84 ++++Gv +++k +HaE+ l + ++++ tl+v++ PC eC FUN_000496-T1 313 HKDEGV-QDKKyPyIIHAEQNALMM-----RNTKNVEGGTLFVTKTPCDECTPL 360 556777.666642479999998884.....567778888************865 PP >> SNAD4 Secreted Novel AID/APOBEC-like Deaminase 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.015 63 54 74 .. 79 99 .. 64 106 .. 0.79 2 ? 7.2 0.0 0.0016 6.9 33 69 .. 328 359 .. 307 368 .. 0.69 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.015 SNAD4 54 sitwylswsPCaeCaekiaef 74 + +++s PC+ C++ +++ FUN_000496-T1 79 NCKVFVSRKPCSFCTKLLVQA 99 45679**********998875 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0016 SNAD4 33 HaEilflekiksreldksksysitwylswsPCaeCae 69 HaE + l + + +++ t++++ +PC eC+ FUN_000496-T1 328 HAEQNALMMRNTKNV-----EGGTLFVTKTPCDECTP 359 777776666555222.....3459***********75 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (418 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 855 (0.0334703); expected 510.9 (0.02) Passed bias filter: 717 (0.0280681); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4094.20 // Query: FUN_000497-T1 [L=454] Description: FUN_000497 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-25 89.8 0.0 1.6e-17 63.7 0.0 2.4 2 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc- 1.9e-16 60.7 0.0 2.8e-09 37.4 0.0 2.4 2 MafB19-deam MafB19-like deaminase 7.2e-06 26.5 0.0 0.065 13.7 0.0 2.3 2 Bd3614-deam Bd3614-like deaminase ------ inclusion threshold ------ 0.033 14.7 0.0 4.2 7.8 0.0 2.6 2 APOBEC_N APOBEC-like N-terminal domain 0.12 12.8 0.1 27 5.2 0.0 2.8 3 AID Activation induced deaminase Domain annotation for each model (and alignments): >> dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 9.5e-09 4.9e-05 25 100 .. 70 135 .. 61 137 .. 0.84 2 ! 63.7 0.0 3.1e-21 1.6e-17 2 100 .. 283 397 .. 282 399 .. 0.94 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 9.5e-09 dCMP_cyt_deam_1 25 pvGavivkkdgeiiatGyngenagndptaHAEvnairkavkeggvklegatlyvtlePCgmCaqaiiesgikkvvv 100 +vGav+v ++i+++ + + + +HA i++ + e++ ++v+ PC+ C+++++++++++v++ FUN_000497-T1 70 KVGAVLVFP--NDISYAIDCSR----NGVHAVARLIMAHPNI---P-EDCKVFVSRKPCSFCTKLLVQAKVERVFY 135 799999994..68999988884....4579999999888733...3.69*************************98 PP == domain 2 score: 63.7 bits; conditional E-value: 3.1e-21 dCMP_cyt_deam_1 2 ekdeklmrlalkaakkaykkskfpvGavivkkdgeiiatGyngenagnd....................ptaHAEvnairkavkeggvklegat 75 ++ + +m+la+ +a++ +++k+ vGavi++k++e+++ G+ng +++ ++HAE+na+++ ++++eg t FUN_000497-T1 283 KQANHFMTLAKFLAQRT-DDPKTGVGAVIIHKNNEVVGLGWNGFPKKALygefarasdkdkrvrgkkypFVIHAEQNALMMRN---TKNIEGGT 372 57889************.**************************9888899*****************99*********9887...55899*** PP dCMP_cyt_deam_1 76 lyvtlePCgmCaqaiiesgikkvvv 100 l+vt PC +C+ ++ gik+vv+ FUN_000497-T1 373 LFVTKAPCDECTPLLEMQGIKTVVL 397 ***********************97 PP >> MafB19-deam MafB19-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 7.4e-08 0.00038 70 104 .. 103 136 .. 85 177 .. 0.82 2 ! 37.4 0.0 5.5e-13 2.8e-09 5 110 .. 286 404 .. 282 426 .. 0.81 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 7.4e-08 MafB19-deam 70 akkklddatlYVtrepCsmCagaiiqaglkslvyg 104 ++ ++d+ ++V r+pCs C ++++qa+++++ y FUN_000497-T1 103 PNI-PEDCKVFVSRKPCSFCTKLLVQAKVERVFYL 136 444.89*************************9885 PP == domain 2 score: 37.4 bits; conditional E-value: 5.5e-13 MafB19-deam 5 eafrkalelveeaidadevkigavvv.kdkkvigvnsn...............dkvtekelkaka.teHaEilalqrAtkklakkklddatlYVtr 83 + f+ +++ + +++d + +gav++ k+++v+g++ n dk + +k+++ HaE +al+ ++k+ ++ tl+Vt+ FUN_000497-T1 286 NHFMTLAKFLAQRTDDPKTGVGAVIIhKNNEVVGLGWNgfpkkalygefarasDKDKRVRGKKYPfVIHAEQNALMMR----NTKNIEGGTLFVTK 377 67899999999***************8999*******************8888555555555555267*****99866....34445789****** PP MafB19-deam 84 epCsmCagaiiqaglkslvygagdlkg 110 pC+ C ++ g+k++v + ++g FUN_000497-T1 378 APCDECTPLLEMQGIKTVVLSDDLEEG 404 ******************988775554 PP >> Bd3614-deam Bd3614-like deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 1.3e-05 0.065 51 86 .. 102 133 .. 73 148 .. 0.81 2 ! 10.3 0.0 0.00015 0.76 34 73 .. 352 386 .. 345 400 .. 0.81 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.3e-05 Bd3614-deam 51 rrpleagarllvtlqcCkmCAalvvaaaddpgrlkv 86 ++++ +++v+ ++C C l+v+a ++ +v FUN_000497-T1 102 HPNIPEDCKVFVSRKPCSFCTKLLVQAKVE----RV 133 3679*******************9999874....44 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00015 Bd3614-deam 34 vLHAevnLlapllreearrpleagarllvtlqcCkmCAal 73 v+HAe n l+ ++ + +e g +l+vt +C C l FUN_000497-T1 352 VIHAEQNALMMRNT----KNIE-GGTLFVTKAPCDECTPL 386 78***998876554....5576.5679**********876 PP >> APOBEC_N APOBEC-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.014 71 68 87 .. 108 127 .. 89 133 .. 0.81 2 ? 7.8 0.0 0.00082 4.2 45 84 .. 352 386 .. 332 396 .. 0.74 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.014 APOBEC_N 68 evtlyvswSPCveCaeelak 87 ++vs PC C + l++ FUN_000497-T1 108 DCKVFVSRKPCSFCTKLLVQ 127 5679***********99987 PP == domain 2 score: 7.8 bits; conditional E-value: 0.00082 APOBEC_N 45 elHaEeaflealsdlvlepselyevtlyvswSPCveCaee 84 +HaE+ l + +++++ tl+v++ PC eC FUN_000497-T1 352 VIHAEQNALMM-----RNTKNIEGGTLFVTKAPCDECTPL 386 57777777763.....567777778************865 PP >> AID Activation induced deaminase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.012 59 6 40 .. 93 127 .. 89 143 .. 0.77 2 ? -2.1 0.0 1 5.2e+03 40 57 .. 165 182 .. 156 189 .. 0.82 3 ? 5.2 0.0 0.0054 27 17 36 .. 366 385 .. 349 395 .. 0.76 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.012 AID 6 haeikfikdnkipseitelwikksPchecsekllk 40 ha+ i + e ++++ + Pc+ c++ l++ FUN_000497-T1 93 HAVARLIMAHPNIPEDCKVFVSRKPCSFCTKLLVQ 127 5666666666666677899***********98876 PP == domain 2 score: -2.1 bits; conditional E-value: 1 AID 40 khfkslplkptlfiGria 57 ++fk +p+ ++f+ ++a FUN_000497-T1 165 NLFKVSPISQNIFVPKVA 182 789999999999998886 PP == domain 3 score: 5.2 bits; conditional E-value: 0.0054 AID 17 ipseitelwikksPchecse 36 e +l+++k+Pc ec+ FUN_000497-T1 366 KNIEGGTLFVTKAPCDECTP 385 5556679***********85 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (454 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 589 (0.0230573); expected 510.9 (0.02) Passed bias filter: 488 (0.0191035); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4607.04 // Query: FUN_000498-T1 [L=963] Description: FUN_000498 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-69 235.1 0.2 7.1e-69 232.8 0.0 2.2 2 ALS2CR8 Amyotrophic lateral sclerosis 2 chromosomal region Domain annotation for each model (and alignments): >> ALS2CR8 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 232.8 0.0 2.8e-73 7.1e-69 1 234 [. 195 408 .. 195 409 .. 0.97 2 ? -1.4 0.1 0.095 2.4e+03 131 156 .. 694 727 .. 691 771 .. 0.69 Alignments for each domain: == domain 1 score: 232.8 bits; conditional E-value: 2.8e-73 ALS2CR8 1 kskakpktrlmwksqsipfdgiPFvvigtk..vleCqyGkdkdsrrkglqekksaedenskkrrktkkskKadCpArikikkirkFpeykvekdpk 94 +s+akp+ rlmwksq++p+dgiPF+++g++ v+eCqyG +rrkg +kk++++++ + k ++ +CpAri++kk+rkFpe+++ dp+ FUN_000498-T1 195 PSSAKPSIRLMWKSQYVPYDGIPFLNTGRRatVMECQYG----PRRKGAVNKKQMDYDEH---GNPLKRHRPTCPARIYVKKVRKFPEFRI--DPN 281 5789***********************************....*****************...999999**********************..*** PP ALS2CR8 95 rekkkvrdelkkdllaLknkpveiegelrfyvklpliseHeghdleeventlepakkqlklqsikedqskkksrldpqvkekiaelvaagldsike 190 +e k+vr++++++l+aL+ + v+++ge+r+yv+lpl +He+hd+++ l+p ++ + +rl+p+v +ki+elva+g+ i+ FUN_000498-T1 282 LEGKNVRQAQERALTALRLAGVNVGGEERYYVQLPLPIAHEYHDMDDIP--LDP-----------DESDGQGQRLNPDVMHKIRELVARGVAGIYV 364 ***********************************************99..877...........6677899************************ PP ALS2CR8 191 vkkqlkkfvekelfkakkvpekenkrffptvrdiknhiheaqkt 234 vk++lk++vekelf++ + p+++nk++fpt+ di+nhih+aq++ FUN_000498-T1 365 VKHCLKEYVEKELFANMEPPPRHNKSYFPTIIDIQNHIHQAQMA 408 *****************************************986 PP == domain 2 score: -1.4 bits; conditional E-value: 0.095 ALS2CR8 131 iseHeghdleeventlepakkqlkl........q 156 is H+++++++++ +++++ k+ FUN_000498-T1 694 ISSHNAKQIKTEQDRMDDEPPPHKRqvldvdftS 727 6789999999999999988887777445555552 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (963 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1247 (0.0488158); expected 510.9 (0.02) Passed bias filter: 554 (0.0216872); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.42u 0.36s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 9341.63 // Query: FUN_000499-T1 [L=1035] Description: FUN_000499 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-66 223.3 0.0 2.3e-65 221.1 0.0 2.0 1 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase Domain annotation for each model (and alignments): >> PDEase_I 3'5'-cyclic nucleotide phosphodiesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 221.1 0.0 9e-70 2.3e-65 1 226 [. 642 902 .. 642 905 .. 0.91 Alignments for each domain: == domain 1 score: 221.1 bits; conditional E-value: 9e-70 PDEase_I 1 YHnfrHAvdVlqtlylll.....................................kktklkevltdleilalliaalcHDvdHpGvnNaFliktks 59 YHn++HA dVl+ ++++ + + l + + +le lal++aa +HD+dHpG++NaFl+ t s FUN_000499-T1 642 YHNSIHASDVLHGVFFMTtskipgfcpvnsklsndsdtdsdsalnggerqkttggCYGVLMDSIPQLELLALYTAATMHDYDHPGRTNAFLVGTLS 737 9**************************99999999999988888877666554444444455999******************************* PP PDEase_I 60 elailYndssvlEnhHlalafkilqk.eelnilsnlskeeykevrkliislIlaTDmakhfellkkfkelleekkkeekkkeeeedrrllllslli 154 + a+lYnd+svlEnhH+a+af++l + +++n+l +l++ e+k++r l i++IlaTD+++hf+ll++f+++++e ++ ++e+dr ll l+++i FUN_000499-T1 738 QQALLYNDRSVLENHHAAAAFTLLMSdPKYNFLCELEPVEFKRFRFLAIEAILATDLKRHFDLLSEFNAKISEGGG-VDW-TQEADR-LLTLQICI 830 **********************998736*******************************************98664.666.444555.5555**** PP PDEase_I 155 kaaDisnpakpfelskkwaelvleEffeqgdkekelglpvsplmdrektelaksqigFidfivlplfealak 226 k+aDis p+k +l+ +w+++++eEf+eqgd e ++g+p+sp m+r+ ++a++q +Fi+ +v pl++a a+ FUN_000499-T1 831 KMADISGPSKGRDLHTRWTKRIVEEFYEQGDDESARGMPISPYMNRDVPHVAQLQESFINHLVAPLYNAYAN 902 ***********************************************99******************99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1035 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1581 (0.0618908); expected 510.9 (0.02) Passed bias filter: 757 (0.029634); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.46u 0.38s 00:00:00.84 Elapsed: 00:00:00.41 # Mc/sec: 10095.78 // Query: FUN_000500-T1 [L=268] Description: FUN_000500 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-56 192.6 13.1 1.2e-56 192.3 13.1 1.1 1 Tetraspanin Tetraspanin family 0.009 15.8 6.1 0.009 15.8 6.1 1.5 2 UbiA UbiA prenyltransferase family ------ inclusion threshold ------ 0.12 12.0 0.9 0.22 11.1 0.9 1.4 1 TMEM206 TMEM206 protein family Domain annotation for each model (and alignments): >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 192.3 13.1 1.5e-60 1.2e-56 1 222 [. 12 247 .. 12 250 .. 0.91 Alignments for each domain: == domain 1 score: 192.3 bits; conditional E-value: 1.5e-60 xxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 1 lkyllfllnllflllGllllavGvwl..ksleaassalsesseaaalipvllivlGaviflvgflGccgalkesrcllllyfvlllllflaelaag 94 +kyllf++n++f+l+G l +a+G+++ + ++a ++ ++ ++a++ li++G+++f++gf Gc+gal+e+ cll +++v+l ++f+++l ++ FUN_000500-T1 12 VKYLLFFFNVFFWLIGGLTVAIGLYArfE-KTAYQDFFNDIVMDPAFA---LIIVGGIMFILGFTGCIGALRENVCLLKFFSVILAIIFFLQLSLA 103 7*************************742.356667777888888888...********************************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxx........ RF Tetraspanin 95 ilafvyrdkekeelsnwlkksledsyedasdlkskkeealdslqeelkCCGvnsysDw..........eksendgvPesCcknsesat........ 172 +++fv++dk ++ ++n++++++ sy+d+ dl + ++d +q+e++CCG ++y+Dw ++ e++gvP+sCc++++ +t FUN_000500-T1 104 VVVFVFQDKVEDIVANKIRSTI-VSYRDNVDL----QVLIDGIQQEFQCCGGKTYDDWgdniyfncssPGAEACGVPFSCCREDTINTqcgygirh 194 *********9999999999999.889999998....89********************************************9999889*****88 PP ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 173 ....alsndssilykegCkekleeflrknlkiigavvialgviqllgiilaccl 222 + + i y++gC+e++++++++n+ +ig+v+++++++q++gi++a l FUN_000500-T1 195 kvhtETFRNGVI-YTRGCIEAVKKWFKDNMFVIGGVAVGIALLQIIGICFANSL 247 765433333444.6************************************9877 PP >> UbiA UbiA prenyltransferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 6.1 1.1e-06 0.009 78 184 .. 17 131 .. 8 138 .. 0.79 2 ? -2.7 0.1 0.46 3.9e+03 118 128 .. 225 235 .. 205 248 .. 0.55 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.1e-06 UbiA 78 llglllllllnpltallgllalllyvlYtlrlKrftllnqvvgglagalppllgwaavtgsl..........sllalllflalflwtwaialanal 163 +++ ++++l++ lt+++gl a + ++Y+ ++ + + + + ++g++ ++lg++ + g l s+ ++++f++++ +++ ++ + FUN_000500-T1 17 FFFNVFFWLIGGLTVAIGLYARFEKTAYQDFFNDIVMDPAFALIIVGGIMFILGFTGCIGALrenvcllkffSVILAIIFFLQLSLAVVVFVF--- 109 333344488888888888888888889999999999999999999999999999999999999*****8777777777777777777777776... PP UbiA 164 rdvedD.rkaGiktlpvvlGrk 184 +d+ +D + i+++ v + ++ FUN_000500-T1 110 QDKVEDiVANKIRSTIVSYRDN 131 ******9999999998877655 PP == domain 2 score: -2.7 bits; conditional E-value: 0.46 UbiA 118 vvgglagalpp 128 v+gg+a +++ FUN_000500-T1 225 VIGGVAVGIAL 235 33333333322 PP >> TMEM206 TMEM206 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.9 2.6e-05 0.22 6 48 .. 82 127 .. 79 141 .. 0.72 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 2.6e-05 TMEM206 6 tclknvfsvlliliylllm..avavflayqtitdf.reklkhpvms 48 +cl +fsv+l +i++l av vf+ + + d+ +k++ ++s FUN_000500-T1 82 VCLLKFFSVILAIIFFLQLslAVVVFVFQDKVEDIvANKIRSTIVS 127 7**********99988754116667777777888625677766654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (268 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1558 (0.0609904); expected 510.9 (0.02) Passed bias filter: 750 (0.02936); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2652.10 // Query: FUN_000501-T1 [L=309] Description: FUN_000501 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.8e-31 108.0 20.3 1.2e-28 100.8 20.3 2.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.3e-08 35.4 15.6 4.6e-07 30.4 15.6 2.3 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.15 12.1 18.0 0.029 14.4 12.0 2.4 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.8 20.3 1.5e-32 1.2e-28 1 260 [] 17 264 .. 17 264 .. 0.90 Alignments for each domain: == domain 1 score: 100.8 bits; conditional E-value: 1.5e-32 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN++Vi++i+ +++l+t+ n +l+LavaDl v+++v+p+ ++ ++ ++ + + +++ ++ ++ + s+ +l+++ +DRY+aIv+plky ++ FUN_000501-T1 17 GNGFVIYLIVSTRSLHTMPNWSVLSLAVADLSVGATVFPLLFALNI--NNLDGPPIHERVFFLVSRTFAFFSVTNLFVMILDRYVAIVHPLKYLSV 110 8*****************************************9999..889999999999************************************ PP xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF 7tm_1 97 rtkrralvlilvvWvlalll.slppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.. 189 + rr++v ++++W++ + + slp+++ + + ++++l+ ++l+ +lp+++ +++ vri+ +r+ +k++++ FUN_000501-T1 111 IRTRRTIVALAIAWIAPIFVfSLPFAIEI----------------EVQ------GQFLLLFRVLLFQILPIIIFIFVTVRIFLIMRRISKRRSQif 184 **************996655055555522................222......247888888888888***********************9999 PP .............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .............kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + +s r+++ a+k++++++++fv+c++ + ++ ++ ++ ++++++ ++++ll ++ns+ NPi Y FUN_000501-T1 185 aqlafnhapkhptAELRSGRENKAAAKMTVAIIFFFVICYVVENYKCFCIVF----KMIETDPALDQLCNLLFVINSAANPIAY 264 999999999998755556666779********************99999999....9*************************99 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 15.6 5.4e-11 4.6e-07 3 278 .. 9 280 .. 7 282 .. 0.62 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 5.4e-11 7tm_4 3 lvyliillGnltilfvikteaslhq.PmylflallalidlglsastlPtvlGiflvdareisfeacllqlffi..hkfsllesavllamavdrfva 95 l+ +++++Gn+ ++++i + +slh P + l+ la++dl + a+ +P ++ ++ +++ ++ff+ +f+++ + l m +dr+va FUN_000501-T1 9 LLTIVTVVGNGFVIYLIVSTRSLHTmPNWSVLS-LAVADLSVGATVFPLLFA---LNINNLDGPPIHERVFFLvsRTFAFFSVTNLFVMILDRYVA 100 56799*******************746777766.8*************8654...4444554445555555552267999999************* PP 7tm_4 96 iysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsygli 191 i++pl+y ++ ++ + ++l ++ + i+v+ l+f + ++ g+ l +l + l + + v i+ ++ +s+ +++ + FUN_000501-T1 101 IVHPLKYLSVIRTRR-TIVALAIAWIAPIFVFSLPFAIE-IEVQGQFLLLFRVLLFQILPIIIFIFVTVR-IFLIMRRISKRRSQIFAQLAFNHAP 193 *******87665543.34555566666677777777765.344555555555555544444433333332.3333344444444444433333334 PP 7tm_4 192 lrtvlgiasreerkkalntcgshvca.vlafyvPmigl.svvhrfgkkvsrllqvllanlyllfPPvlnPivysvktkeirdavvkill 278 + ++ s+ e k a + ++ ++ v+ + v +v ++ + + l q l+nl +++ nPi y+ ++i+ ++ k+l+ FUN_000501-T1 194 KHPTAELRSGRENKAAAKMTVAIIFFfVICYVVENYKCfCIVFKMIETDPALDQ--LCNLLFVINSAANPIAYAFLKRDIKMTLLKMLT 280 566667777666666666555555541444444444331355555555555443..456666667777777777777777777777775 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 12.0 3.5e-06 0.029 5 128 .. 12 133 .. 8 182 .. 0.89 2 ? 0.6 0.3 0.058 5e+02 128 145 .. 216 233 .. 204 298 .. 0.59 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 3.5e-06 7TM_GPCR_Srx 5 liGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsellkellnshliglialglYeisplsqllialNRfcavffpl 100 ++ +v N +v++ i+++ sl++ ++ ls a++++ + ++++ + + + + + + ++++ +++ l++ ++ +s +++ l+R +a++ pl FUN_000501-T1 12 IVTVVGNGFVIYLIVSTRSLHTMPNWSVLSLAVADLSVGATVFPLLFALNINNLDG-PPIH-ERVFFLVSRTFAFFSVTNLFVMILDRYVAIVHPL 105 566789********************************999999888888877777.4443.5699999999999999999*************** PP 7TM_GPCR_Srx 101 kyekifsiknTkiiiviiwivslifitv 128 ky ++ +++ T+++++i+wi +++ + FUN_000501-T1 106 KYLSVIRTRRTIVALAIAWIAPIFVFSL 133 ********************99986443 PP == domain 2 score: 0.6 bits; conditional E-value: 0.058 7TM_GPCR_Srx 128 vlylpegCkllynpetlt 145 +++++ C+++ n++ + FUN_000501-T1 216 IIFFFVICYVVENYKCFC 233 222222233332222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1281 (0.0501468); expected 510.9 (0.02) Passed bias filter: 458 (0.0179291); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3055.29 // Query: FUN_000502-T1 [L=481] Description: FUN_000502 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-76 255.2 0.1 2e-75 254.1 0.0 1.5 2 Pkinase Protein kinase domain 7.1e-46 156.0 0.0 1.5e-45 155.0 0.0 1.5 1 CaMKII_AD Calcium/calmodulin dependent protein kinase I 3.2e-37 128.7 0.0 4.3e-37 128.3 0.0 1.1 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 7.5e-08 33.3 0.0 1.4e-07 32.4 0.0 1.5 1 DUF4440 Domain of unknown function (DUF4440) 0.00096 19.9 0.0 0.0018 19.1 0.0 1.4 1 SnoaL_3 SnoaL-like domain 0.0016 18.4 0.2 0.0038 17.2 0.2 1.6 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.0049 16.1 1.0 0.0066 15.7 0.0 1.6 2 Pkinase_fungal Fungal protein kinase ------ inclusion threshold ------ 0.017 14.7 0.2 0.065 12.9 0.1 1.9 2 ABC1 ABC1 atypical kinase-like domain 0.076 13.2 0.0 1.6 8.8 0.0 2.4 2 FTA2 Kinetochore Sim4 complex subunit FTA2 0.22 11.6 0.9 0.8 9.8 0.6 2.0 2 RIO1 RIO domain 0.25 11.6 0.0 4.5 7.5 0.0 2.1 2 APH Phosphotransferase enzyme family Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 254.1 0.0 8.6e-79 2e-75 1 262 [] 12 270 .. 12 270 .. 0.96 2 ? -2.2 0.0 1.3 3.1e+03 184 243 .. 300 362 .. 300 370 .. 0.46 Alignments for each domain: == domain 1 score: 254.1 bits; conditional E-value: 8.6e-79 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgals 96 ye++e+lG+G+f+ V k+v ke + ++A+K+++++k+++++ +kv rE +i + lkhpnivrl++++ e+ +ylv+++v+ggelf+ + ++ +s FUN_000502-T1 12 YEIKEELGRGAFSIVRKCVLKEGKVEFAVKILDTRKMTSRDIQKVEREARICRALKHPNIVRLYSSVLEEGFYYLVFDLVTGGELFEEIVAREYYS 107 899************************************999****************************************************** PP Pkinase 97 eeeakkilkqilegleylHsegvvHrDlKpeNiLidekge...lKitDFGlakelesssk.ltsfvgtseYmAPEvlkskkygkkvDvWslGvily 188 e++a++ ++q+l++++++H+ ++vHrDlKpeN+L+++k++ K++DFGla e+++++ f gt+ Y++PE+lk+++y k+vD+W+ Gvily FUN_000502-T1 108 EADASHCIQQVLHSIHHCHEINIVHRDLKPENLLLSSKDKtaiCKLADFGLAIEVDNDKLgWFGFAGTPGYLSPEILKKEPYNKAVDLWASGVILY 203 ************************************66667999*************9988889******************************** PP Pkinase 189 elltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 ll g ppf++e++++ ++++ +++ +pe++s+ +eakdl+kk+l++d++kR+ta+e+l+hpw+ FUN_000502-T1 204 ILLVGYPPFWDEDQQKLYSQIKAG-------AYDFPSPEWDSVTDEAKDLIKKMLTVDQSKRITATEALKHPWI 270 **********77777766666666.......889***************************************7 PP == domain 2 score: -2.2 bits; conditional E-value: 1.3 Pkinase 184 Gvilyelltgkppfsaekekekvekeldqlekilki....elkeklpepssi.seeakdllkkll 243 G il ++l+ ++ ++++ke+ e+ + + ++ ++ + + + p++++ ++e++ l ++l+ FUN_000502-T1 300 GAILTTMLATHNFSGSRRKKESDEEVVAT--QSEETdgssPASVTQPTWKTQkEQEIIRLTQQLI 362 56777776666655544444433333333..2222234563344444444332555555555554 PP >> CaMKII_AD Calcium/calmodulin dependent protein kinase II association domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 155.0 0.0 6.4e-49 1.5e-45 2 127 .. 351 476 .. 350 477 .. 0.99 Alignments for each domain: == domain 1 score: 155.0 bits; conditional E-value: 6.4e-49 CaMKII_AD 2 kqeiiklletlleaisegdfetytklcdpeltvfepevlgnlveglefhrfyfekllakrkkavrttilnkrvrllgddsAviayvrlltlldknG 97 +qeii+l+++l+ +i++ df+ty kl+dp++t+fepe+ gnlveg+efh+fyf++ l +r+ + +ttil ++v++l dsA+i+yvrl++ + G FUN_000502-T1 351 EQEIIRLTQQLITSITTQDFDTYSKLVDPHITAFEPEANGNLVEGVEFHKFYFDNGLRQRNAPTNTTILSPHVHILSADSACISYVRLTQRILSSG 446 89********************************************************************************************** PP CaMKII_AD 98 kkhtrqseetrVwekrdgkWkivhvHrSaa 127 + t qseetrVw+ ++g+W++vh+HrS++ FUN_000502-T1 447 APVTDQSEETRVWQLKNGHWVNVHFHRSSS 476 ****************************86 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 128.3 0.0 1.9e-40 4.3e-37 2 253 .. 13 263 .. 12 267 .. 0.89 Alignments for each domain: == domain 1 score: 128.3 bits; conditional E-value: 1.9e-40 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtl.keeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk 95 e+ke+lG+Gaf+ V k+ lk + k++ avK+l +++ ++++ +++ +ea++ + l+hpniv+l+ ++ee+ +++v+++v+gG+L e + + FUN_000502-T1 13 EIKEELGRGAFSIVRKCVLK----EGKVEFAVKILdTRKMTSRDIQKVEREARICRALKHPNIVRLYSSVLEEGFYYLVFDLVTGGELFEEIVA- 102 6899****************....99*********4456667779**********************************************999. PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse...kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDv 187 +e +s + ++++q+ + +++ ++ ++vHrdl N L+s+ + ++k++DfGLa +v d+++ + +++pE+lk++ ++++ D FUN_000502-T1 103 REYYSEADASHCIQQVLHSIHHCHEINIVHRDLKPENLLLSSkdkTAICKLADFGLAIEV--DNDKLGWFGFAGTPGYLSPEILKKEPYNKAVDL 195 6899999*********************************98555679************..444444556667779****************** PP PK_Tyr_Ser-Thr 188 WsfGvllwEiftlgeepykglkneevlelleeg.erleqp..encpeelyelmkeCweedpeeRptfke 253 W+ Gv+l+ ++ g p+ + +++++++++++g + + p +++++e ++l+k+ + d+++R t +e FUN_000502-T1 196 WASGVILYILLV-GYPPFWDEDQQKLYSQIKAGaYDFPSPewDSVTDEAKDLIKKMLTVDQSKRITATE 263 ********6665.*****************8772556666226899******************99876 PP >> DUF4440 Domain of unknown function (DUF4440) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 0.0 6.1e-11 1.4e-07 1 106 [. 354 467 .. 354 468 .. 0.89 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 6.1e-11 DUF4440 1 iralerallealvagdaealaallapdfvlvgps..gpvldkaellealeaggldyssi....eltdvevrvl.gdvAvvtgrstvearg..dgep 87 i +l ++l ++++++d++++ +l +p ++ + p g ++ + e++ +++++gl+++ + ++ + +v++l d+A++++ +++ r+ g+p FUN_000502-T1 354 IIRLTQQLITSITTQDFDTYSKLVDPHITAFEPEanGNLVEGVEFHKFYFDNGLRQRNAptntTILSPHVHILsADSACISYV-RLTQRIlsSGAP 448 778999*************************88888***************999998888766777799****9999999988.5555554689** PP DUF4440 88 vtvrgrftsvwkkegggWk 106 vt + t+vw+ ++g+W FUN_000502-T1 449 VTDQSEETRVWQLKNGHWV 467 ******************6 PP >> SnoaL_3 SnoaL-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 7.7e-07 0.0018 4 117 .. 357 474 .. 354 476 .. 0.81 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 7.7e-07 SnoaL_3 4 lndafyeaaaegdfdalfalwsddvscigtdasellrgreevrr.swrqifaqt.qglqfelrelrvte.agdvawvte.llnikaeddgeeaege 95 l +++++ ++++dfd++++l +++ ++ + a+ +l e+ + ++++ + q +++ ++ +++v+ + d a++ + l++ + + g++ + + FUN_000502-T1 357 LTQQLITSITTQDFDTYSKLVDPHITAFEPEANGNLVEGVEFHKfYFDNGLRQRnAPTNTTILSPHVHIlSADSACISYvRLTQRILSSGAPVTDQ 452 77999**************************99997766666662567778875258999999999976456666666515666778999999999 PP SnoaL_3 96 lrlTnvlrrtdggWkivhhhlS 117 T v +g W vh h S FUN_000502-T1 453 SEETRVWQLKNGHWVNVHFHRS 474 999***************9988 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.2 1.6e-06 0.0038 106 166 .. 98 156 .. 84 162 .. 0.84 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.6e-06 Kdo 106 edllaqwae.laeelrrallkavgrlirklhragvqHgdlyakhillqtekeeeakasliDl 166 e+++a+ e ++e+ +++v i++ h++++ H+dl + ++ll ++ + a + l D+ FUN_000502-T1 98 EEIVAR--EyYSEADASHCIQQVLHSIHHCHEINIVHRDLKPENLLLSSKD-KTAICKLADF 156 556665..4499999999******************************996.7888888887 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 2.8e-06 0.0066 299 376 .. 122 195 .. 103 207 .. 0.79 2 ? -2.4 0.5 0.88 2e+03 234 271 .. 318 362 .. 236 376 .. 0.40 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2.8e-06 Pkinase_fungal 299 hrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielsessasgarertGTleFmaiellkgeeHtyrhDL 376 ++ + + +i+HrD +N+++ k+++ L D+ laie++ + + g GT +++ e+lk+e + DL FUN_000502-T1 122 IHHCH-EINIVHRDLKPENLLLS--SKDKTAICKLADFGLAIEVD-NDKLGWFGFAGTPGYLSPEILKKEPYNKAVDL 195 44555.889**************..566778889***********.6778899***************8887777777 PP == domain 2 score: -2.4 bits; conditional E-value: 0.88 Pkinase_fungal 234 slrskkkvaslssarkk.......sssl.kpskrsrlenrvhrrlv 271 +++s+++v++++s++++ ++ + k++k++++ r+ + l+ FUN_000502-T1 318 KKESDEEVVATQSEETDgsspasvTQPTwKTQKEQEI-IRLTQQLI 362 1122222222111111122222221222344444443.34444444 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.31 7.1e+02 42 86 .. 22 65 .. 4 83 .. 0.75 2 ? 12.9 0.1 2.8e-05 0.065 145 221 .. 85 165 .. 50 170 .. 0.63 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.31 ABC1 42 SiaqVhkArlkdge.eVavKvqrpgvkkriesDlkllklllkvlkk 86 ++ V k +lk+g+ e avK+ + +k ++D++ +++ +++++ FUN_000502-T1 22 AFSIVRKCVLKEGKvEFAVKIL--DTRKMTSRDIQKVEREARICRA 65 4555889999999999999998..5678888999988888877764 PP == domain 2 score: 12.9 bits; conditional E-value: 2.8e-05 ABC1 145 vLtmeyvdGikiddlealeea...gidrkeiaeklvelfleqifedgffhaDphpGNllvrkdg...elvllDfGlmgeldek 221 +L+ ++v G ++ + ++++ + d+++ +++++++ +++ e +++h D+ p Nll++++ l DfGl e+d++ FUN_000502-T1 85 YLVFDLVTGGELFEE-IVAREyysEADASHCIQQVLHS-IHHCHEINIVHRDLKPENLLLSSKDktaICKLADFGLAIEVDND 165 677777777777442.2222300033334444444443.456778999************988755344578*****999876 PP >> FTA2 Kinetochore Sim4 complex subunit FTA2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.12 2.9e+02 23 60 .. 11 50 .. 4 71 .. 0.73 2 ? 8.8 0.0 0.00069 1.6 174 203 .. 112 141 .. 94 160 .. 0.84 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.12 FTA2 23 diefleyLgeglhsvVvkvkirgk..eYAlKlFrfveaee 60 +e+ e+Lg g+ s+V k ++ e+A+K+ + ++++ FUN_000502-T1 11 MYEIKEELGRGAFSIVRKCVLKEGkvEFAVKILDTRKMTS 50 468999************988876689****976664433 PP == domain 2 score: 8.8 bits; conditional E-value: 0.00069 FTA2 174 vsqlprmlrdlkklhklgIvvrDlkeenyi 203 + ++++l+ ++ h+ Iv rDlk+en++ FUN_000502-T1 112 SHCIQQVLHSIHHCHEINIVHRDLKPENLL 141 456899**********************86 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.67 1.6e+03 8 35 .. 32 60 .. 26 87 .. 0.70 2 ? 9.8 0.6 0.00034 0.8 102 156 .. 104 164 .. 47 170 .. 0.75 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.67 RIO1 8 edgk.evavKiyktgtteFkkvkkyrsgd 35 ++gk e+avKi t + ++++k + FUN_000502-T1 32 KEGKvEFAVKILDTRKMTSRDIQKVEREA 60 44445899999999999999987654443 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00034 RIO1 102 e...eeeaeelyeevleemrklykeaglvHgDLseyNvlvded.kvviI...DvsQaveldh 156 e e +a+++ ++vl++++ e ++vH DL N+l++++ k i D++ a+e+d+ FUN_000502-T1 104 EyysEADASHCIQQVLHSIHHCH-EINIVHRDLKPENLLLSSKdKTAICklaDFGLAIEVDN 164 344578899999*****877766.***************99875554422226666666665 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.11 2.6e+02 33 85 .. 52 98 .. 29 128 .. 0.61 2 ? 7.5 0.0 0.0019 4.5 170 186 .. 130 148 .. 126 159 .. 0.78 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.11 APH 33 aaeelerelallrhLaaagvvpvPrvlagetdaellglpfllmeylpGedler 85 +++ere++++r+L+ + r+++ +++++++l+f l+++ +l + FUN_000502-T1 52 DIQKVEREARICRALKHPNI---VRLYSSVLEEGFYYLVFDLVTG---GELFE 98 44566777777777766644...6888855555555555555554...44444 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0019 APH 170 lvHgDlhpgNllvd..dgg 186 +vH+Dl+p Nll++ d++ FUN_000502-T1 130 IVHRDLKPENLLLSskDKT 148 79***********965544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (481 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 971 (0.0380114); expected 510.9 (0.02) Passed bias filter: 705 (0.0275984); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4610.52 // Query: FUN_000503-T1 [L=705] Description: FUN_000503 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0012 19.6 0.2 0.0056 17.4 0.0 2.2 2 VWA von Willebrand factor type A domain 0.0044 18.1 0.1 2.1 9.5 0.0 3.1 3 VWA_2 von Willebrand factor type A domain ------ inclusion threshold ------ 0.032 14.8 0.0 0.11 13.1 0.0 1.9 1 Peptidase_C1 Papain family cysteine protease 0.045 14.3 0.3 0.11 13.0 0.3 1.6 1 Ribosomal_L37ae Ribosomal L37ae protein family 0.19 12.7 0.0 0.43 11.5 0.0 1.6 1 HATPase_c Histidine kinase-, DNA gyrase B-, and HSP90- 0.25 11.9 1.1 0.63 10.6 1.1 1.7 1 Zn_ribbon_8 Zinc ribbon domain 1.1 9.6 5.7 1.3 9.3 0.3 2.6 2 zf-C2HC_2 zinc-finger of a C2HC-type 1.5 9.0 4.1 50 4.2 4.3 2.6 1 DUF7560 Family of unknown function (DUF7560) 1.7 9.0 0.0 1.7 9.0 0.0 3.2 4 Rad50_zn_hook Rad50 zinc hook motif 2.6 9.2 6.1 5.9 8.1 1.0 3.0 2 zf-C2H2 Zinc finger, C2H2 type 3.6 7.7 4.4 32 4.7 0.4 2.4 2 Sgf11 Sgf11 (transcriptional regulation protein) 6.7 7.0 7.1 1.5 9.2 0.7 2.4 2 zf-HIT HIT zinc finger Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.3 2.8 5.9e+03 4 14 .. 7 17 .. 7 20 .. 0.84 2 ! 17.4 0.0 2.6e-06 0.0056 60 145 .. 237 330 .. 217 361 .. 0.74 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 2.8 VWA 4 fllDgSgsige 14 ++lD Sgs+++ FUN_000503-T1 7 IVLDVSGSMSS 17 79*******64 PP == domain 2 score: 17.4 bits; conditional E-value: 2.6e-06 VWA 60 skeellsavkslkykgggttntgkalkyalenlfkssagaRegapkvvvlltdGksqdg......dveeaarelksagvkvfavgv...gnadee 145 ske + ++s++ g t + +k+a++ lf+++a+ + ++k++++l+dG+++dg ++ a+++l +a+v+v+ + + ++ +++ FUN_000503-T1 237 SKERSRELLQSIEPFIYGRTPFYESIKKATK-LFEDTASKFSIHKKLLFILSDGEPTDGkntdraGIKHAVAKLTAANVTVVSCFItesTQITPR 330 455555566666555555555899*****99.888888844479**************669********************99887554444444 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.023 48 3 14 .. 7 18 .. 5 65 .. 0.92 2 ! 9.5 0.0 0.001 2.1 59 108 .] 238 290 .. 191 290 .. 0.83 3 ? -2.5 0.0 5.1 1.1e+04 72 88 .. 430 448 .. 414 453 .. 0.70 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.023 VWA_2 3 fvlDnSgSmrng 14 +vlD+SgSm+++ FUN_000503-T1 7 IVLDVSGSMSSN 18 8********986 PP == domain 2 score: 9.5 bits; conditional E-value: 0.001 VWA_2 59 kakllealrrleat.gggtdlaaAlqlarkalkkrr..rknakriivlitDge 108 k++ +e l+++e+ g t + + +++a+k+++++ ++ +k+ +++++Dge FUN_000503-T1 238 KERSRELLQSIEPFiYGRTPFYESIKKATKLFEDTAskFSIHKKLLFILSDGE 290 566688899999999******************999999************96 PP == domain 3 score: -2.5 bits; conditional E-value: 5.1 VWA_2 72 t..gggtdlaaAlqlarka 88 + +ggt++a+A + ++ FUN_000503-T1 430 KeqEGGTCYANASAAVLDL 448 445899***9997776665 PP >> Peptidase_C1 Papain family cysteine protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 5.1e-05 0.11 127 204 .. 504 591 .. 482 598 .. 0.64 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.1e-05 Peptidase_C1 127 lkkavakngPvsvaidasekdfqlYksG.......vyket....ecsk.....telnhavllvGygtengkdyWivkNsWgtdwgekGYiriar 204 +ka+ +++Pv + ++ +++++ ++ + +++++ + ++ hav+l ++++ + + NsWg w ++G++++++ FUN_000503-T1 504 AMKAIIAKRPVVARFRLTDDEWDSFGKFfkskptsILTKKeidiT--ArppntRTGGHAVVLTSFNSQ----CLRLMNSWGVGWADQGFFKVQN 591 555666667777777666664433332211123335444433221..122333456888888888876....9999***************986 PP >> Ribosomal_L37ae Ribosomal L37ae protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.3 5.3e-05 0.11 17 59 .. 623 668 .. 614 673 .. 0.68 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 5.3e-05 Ribosomal_L37ae 17 aslrkrvkkieisqhakytCpfcgkkkvkRkavgi...weckkcgk 59 + +r+ +++ ++ q+a+ytCp+c + + +g +c kc++ FUN_000503-T1 623 QVARRLMNSYQALQRAEYTCPKCSRPSPVMGFTGTllqATCPKCSR 668 4579999****************99865444444411235666655 PP >> HATPase_c Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.0002 0.43 10 85 .. 34 124 .. 29 135 .. 0.73 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.0002 HATPase_c 10 lsnlldNaikh...............aakageievtleadg.deleitveDnGpGippedleklfepfsr.dsrkrkgggtGlGLsivrk.lve 85 + ++dN i+h ++ +g +v ++++ ++ i+v+++G+ + e+++++fe + r + ++ + G ++vr+ l++ FUN_000503-T1 34 IFDVIDNLIRHdvssdnhvfaigvgaSSGGGVFDVIATVKQfQNQGISVQNTGEPATHEHIKRIFEILERaG---ARTIRKWAGVYVVREaLSD 124 56789999999887777777777764335555566666644589**********************888821...1222233477777776655 PP >> Zn_ribbon_8 Zinc ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 1.1 0.0003 0.63 5 33 .. 639 667 .. 639 671 .. 0.77 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0003 Zn_ribbon_8 5 eYrCedCgheFevlqkmsdaplta.CPeCg 33 eY C +C + v+ ++ + l+a CP+C FUN_000503-T1 639 EYTCPKCSRPSPVMG-FTGTLLQAtCPKCS 667 8*******8888888.664455555****6 PP >> zf-C2HC_2 zinc-finger of a C2HC-type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.8 0.12 2.6e+02 4 10 .. 641 647 .. 639 647 .. 0.91 2 ? 9.3 0.3 0.00062 1.3 4 13 .. 662 671 .. 660 673 .. 0.86 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.12 zf-C2HC_2 4 pCpiCGR 10 +Cp+C+R FUN_000503-T1 641 TCPKCSR 647 7*****9 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00062 zf-C2HC_2 4 pCpiCGRkFn 13 +Cp+C+R+F FUN_000503-T1 662 TCPKCSRSFS 671 7********6 PP >> DUF7560 Family of unknown function (DUF7560) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 4.3 0.023 50 4 40 .. 638 673 .. 636 674 .. 0.76 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.023 DUF7560 4 yeFtCPeCgeeieVdesmReallenGCvvCgasVsed 40 e tCP+C++ +V + +ll++ C+ C +s s++ FUN_000503-T1 638 AEYTCPKCSRPSPVMG-FTGTLLQATCPKCSRSFSTN 673 6789999999999965.56788888899888887765 PP >> Rad50_zn_hook Rad50 zinc hook motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.0 0.3 9.3 2e+04 27 39 .. 234 246 .. 233 248 .. 0.69 2 ? -3.3 0.0 5.4 1.2e+04 34 43 .. 467 476 .. 465 477 .. 0.80 3 ? 3.0 0.3 0.06 1.3e+02 17 28 .. 637 648 .. 631 648 .. 0.77 4 ? 9.0 0.0 0.00078 1.7 21 34 .. 662 676 .. 659 681 .. 0.81 Alignments for each domain: == domain 1 score: -4.0 bits; conditional E-value: 9.3 Rad50_zn_hook 27 RpLdeehrseLik 39 ++L+ e+ +eL++ FUN_000503-T1 234 KELSKERSRELLQ 246 5788888777766 PP == domain 2 score: -3.3 bits; conditional E-value: 5.4 Rad50_zn_hook 34 rseLikklqs 43 rse+ik++ s FUN_000503-T1 467 RSEFIKRYGS 476 89****9976 PP == domain 3 score: 3.0 bits; conditional E-value: 0.06 Rad50_zn_hook 17 eaegcCPlCgRp 28 ae CP C+Rp FUN_000503-T1 637 RAEYTCPKCSRP 648 45568******8 PP == domain 4 score: 9.0 bits; conditional E-value: 0.00078 Rad50_zn_hook 21 cCPlCgRpLdeeh.r 34 CP C+R++++++ FUN_000503-T1 662 TCPKCSRSFSTNDgQ 676 7*********98755 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.3 0.18 3.9e+02 1 8 [. 640 647 .. 640 650 .. 0.88 2 ? 8.1 1.0 0.0028 5.9 2 14 .. 662 674 .. 662 675 .. 0.91 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.18 zf-C2H2 1 ykCpdCgk 8 y+Cp+C + FUN_000503-T1 640 YTCPKCSR 647 99****87 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0028 zf-C2H2 2 kCpdCgksFsrks 14 +Cp+C +sFs+++ FUN_000503-T1 662 TCPKCSRSFSTND 674 6*********986 PP >> Sgf11 Sgf11 (transcriptional regulation protein) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.4 0.015 32 4 13 .. 639 648 .. 636 648 .. 0.84 2 ? 4.2 0.3 0.021 45 6 16 .. 662 672 .. 660 673 .. 0.82 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.015 Sgf11 4 yvtCpnCgRq 13 +tCp+C+R+ FUN_000503-T1 639 EYTCPKCSRP 648 689******5 PP == domain 2 score: 4.2 bits; conditional E-value: 0.021 Sgf11 6 tCpnCgRqiaa 16 tCp+C+R+ ++ FUN_000503-T1 662 TCPKCSRSFST 672 8******8665 PP >> zf-HIT HIT zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.7 0.00069 1.5 11 22 .. 637 648 .. 635 649 .. 0.85 2 ? 0.6 0.9 0.33 6.9e+02 15 20 .. 662 667 .. 662 670 .. 0.83 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00069 zf-HIT 11 pskYrCpkCgvr 22 + Y+CpkC+ + FUN_000503-T1 637 RAEYTCPKCSRP 648 589******976 PP == domain 2 score: 0.6 bits; conditional E-value: 0.33 zf-HIT 15 rCpkCg 20 +CpkC+ FUN_000503-T1 662 TCPKCS 667 7****8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (705 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 942 (0.0368761); expected 510.9 (0.02) Passed bias filter: 812 (0.031787); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.42u 0.36s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6746.17 // Query: FUN_000504-T1 [L=323] Description: FUN_000504 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (323 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1603 (0.062752); expected 510.9 (0.02) Passed bias filter: 939 (0.0367587); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.42s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3185.83 // Query: FUN_000506-T1 [L=710] Description: FUN_000506 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (710 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 512 (0.0200431); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.43 # Mc/sec: 6680.04 // Query: FUN_000507-T1 [L=258] Description: FUN_000507 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (258 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 347 (0.0135839); expected 510.9 (0.02) Passed bias filter: 300 (0.011744); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2674.55 // Query: FUN_000508-T1 [L=146] Description: FUN_000508 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.02 14.4 2.3 0.023 14.3 2.3 1.0 1 DUF2252 Uncharacterized protein conserved in bacteria 0.046 14.4 1.6 0.046 14.4 1.6 2.0 2 DUF2383 Domain of unknown function (DUF2383) 0.13 11.2 0.9 0.16 11.0 0.9 1.0 1 Het-C Heterokaryon incompatibility protein Het-C 0.25 12.0 3.4 0.55 10.9 0.7 2.2 2 TRIP13_N TRIP13 N-terminal domain 0.26 11.1 10.9 0.31 10.9 10.9 1.0 1 Moulting_cycle Moulting cycle 0.58 10.8 4.8 1.2 9.8 4.8 1.5 1 SesA N-terminal domain on NACHT_NTPase and P-loop 0.86 9.9 12.6 2.6 8.3 0.4 2.1 2 Syntaxin Syntaxin 1.7 9.2 6.0 0.84 10.2 3.6 1.5 1 Spore_III_AF Stage III sporulation protein AF (Spore_III_A Domain annotation for each model (and alignments): >> DUF2252 Uncharacterized protein conserved in bacteria (DUF2252) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 2.3 7.1e-06 0.023 100 191 .. 18 99 .. 12 137 .. 0.68 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 7.1e-06 DUF2252 100 ekdarrlvraaaesYrerirelaemstldvwyeridvelleeatseevkgvlrealekarrrtreallaklteleggkrrikdeppkllhls 191 +k r+ +r+++++Y+++ r+ +++ +++w d+ ++++a+++ k+++r+++e+ r+++ +l a++ e+++++ r +++++h+ FUN_000508-T1 18 KKVLRDTIREIVQEYKQAQRR--QRWRDAIW----DIIQQKRAKKDRLKRMVRKMAEQRRKQKATELRARIREQQEDRSR----DENVFHIG 99 556677777777777776544..44444556....678899999999999999999999999888887777777744333....33455554 PP >> DUF2383 Domain of unknown function (DUF2383) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 0.51 1.6e+03 27 47 .. 16 36 .. 13 39 .. 0.74 2 ? 14.4 1.6 1.4e-05 0.046 25 80 .. 52 105 .. 50 123 .. 0.74 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.51 DUF2383 27 vkdpalktllqriaeerreaa 47 ++++ l+++ ++i +e+++a FUN_000508-T1 16 ARKKVLRDTIREIVQEYKQAQ 36 667778888888888888765 PP == domain 2 score: 14.4 bits; conditional E-value: 1.4e-05 DUF2383 25 ekvkdpalktllqriaeerr.eaaeeLqseirelggepeeggsfaGklhrawvslks 80 +++k+++lk + +++ae+rr ++a+eL++ ire+++++ + + h ++ +++s FUN_000508-T1 52 KRAKKDRLKRMVRKMAEQRRkQKATELRARIREQQEDRSRDENV---FHIGINDVDS 105 6899************998725699********99988776654...3555555555 PP >> Het-C Heterokaryon incompatibility protein Het-C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.9 4.9e-05 0.16 277 363 .. 14 109 .. 10 125 .. 0.76 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 4.9e-05 Het-C 277 GeasDkltqsevdeldealkeaekss...........sssssksalksllsklpgvgddlaeeaeelkakseaqeaenaaseekanavpgvspefd 361 ea+ k+ + + e+ ++ k+a++++ +++++k+ lk +++k+ + +++a+el+a+ +q+++++++e+ + + ++fd FUN_000508-T1 14 CEARKKVLRDTIREIVQEYKQAQRRQrwrdaiwdiiqQKRAKKDRLKRMVRKMAE--QRRKQKATELRARIREQQEDRSRDENVFHIGINDVDSFD 107 6889999999999*9999999999999999***999888889999*******997..44689999*****99999988866555444333334444 PP Het-C 362 pe 363 ++ FUN_000508-T1 108 SD 109 43 PP >> TRIP13_N TRIP13 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 0.15 4.7e+02 15 30 .. 17 32 .. 9 46 .. 0.62 2 ? 10.9 0.7 0.00017 0.55 14 70 .. 50 110 .. 47 125 .. 0.79 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.15 TRIP13_N 15 sstartdtireaVekl 30 ++ + +dtire V+++ FUN_000508-T1 17 RKKVLRDTIREIVQEY 32 3445556666666655 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00017 TRIP13_N 14 psstartdtireaVeklLe...nfsvlsldseitgfeddpflaenVerIavcesde...eese 70 +++ a++d +++ V+k+ e +++ ++l +i++ ++d+ enV +I + ++d+ + + FUN_000508-T1 50 QQKRAKKDRLKRMVRKMAEqrrKQKATELRARIREQQEDRSRDENVFHIGINDVDSfdsD--N 110 57789999999***9999862335689999*********************999987432..3 PP >> Moulting_cycle Moulting cycle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 10.9 9.6e-05 0.31 8 94 .. 24 107 .. 18 127 .. 0.59 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 9.6e-05 Moulting_cycle 8 hLtktvralknkekeskWqdiierikekserikkrkkveellkkrlsvfteakkanprkaseeselkkekkvke.eslkeladlekyi 94 + ++v+ k+ ++ ++W+d i +i ++++ k + +++++k +++ ++k ++ r ++ e+ +++++++e ++d++ + FUN_000508-T1 24 TIREIVQEYKQAQRRQRWRDAIWDIIQQKRAKK--DRLKRMVRKMAEQRRKQKATELRARIREQ--QEDRSRDEnVFHIGINDVDSFD 107 577889999999*************88776544..44566666666666555555444444444..2333333323444555555443 PP >> SesA N-terminal domain on NACHT_NTPase and P-loop NTPases # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 4.8 0.00037 1.2 37 103 .. 20 86 .. 7 93 .. 0.82 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00037 SesA 37 lvqetLeaiksqleeskldedteaaikpllesCkekatklkeifekvapapedsrleryrkavrslg 103 + ++t ++i ++ ++++ + ++ai +++++ ++k ++lk++ +k+a++ +++ ++ r+ +r+++ FUN_000508-T1 20 VLRDTIREIVQEYKQAQRRQRWRDAIWDIIQQKRAKKDRLKRMVRKMAEQRRKQKATELRARIREQQ 86 5678888888888888888888888999999999999999999999999999999988888887744 PP >> Syntaxin Syntaxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.4 0.00081 2.6 80 118 .. 3 41 .. 1 45 [. 0.89 2 ? 5.5 8.7 0.0059 19 46 95 .. 38 87 .. 35 92 .. 0.91 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00081 Syntaxin 80 ksgegsavdRirksqtaaLrkklkevMleynelrekire 118 ++++ + Ri + ++Lr +e+++ey++++ ++r FUN_000508-T1 3 QPQPRRRSLRICEARKKVLRDTIREIVQEYKQAQRRQRW 41 567788889*************************99985 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0059 Syntaxin 46 kkrmesdikevkkraesikarLealdksneenekksgegsavdRirksqt 95 ++r i ++ ++ ++ k rL+++ ++ +e+++k++++ +Rir q FUN_000508-T1 38 RQRWRDAIWDIIQQKRAKKDRLKRMVRKMAEQRRKQKATELRARIREQQE 87 77888889999999********************************9885 PP >> Spore_III_AF Stage III sporulation protein AF (Spore_III_AF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 3.6 0.00026 0.84 54 126 .. 48 120 .. 37 123 .. 0.84 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00026 Spore_III_AF 54 lseseeeekeeikkngeklkeeqkkealeeykkqlekqveallklnegykvakveveidedeeseefgeikev 126 + ++++++k+ +k+ ++k++e+ +k+ +e + ++++q e++ ++ + + + +v+ + +++ee++++ ++ FUN_000508-T1 48 IIQQKRAKKDRLKRMVRKMAEQRRKQKATELRARIREQQEDRSRDENVFHIGINDVDSFDSDNDEEIEHVHRI 120 457888999************************************************5555555466666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (146 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3578 (0.140067); expected 510.9 (0.02) Passed bias filter: 1157 (0.0452926); expected 510.9 (0.02) Passed Vit filter: 130 (0.00508906); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.31u 0.44s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 1446.18 // Query: FUN_000509-T1 [L=348] Description: FUN_000509 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (348 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 576 (0.0225484); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3412.38 // Query: FUN_000510-T1 [L=125] Description: FUN_000510 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (125 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1108 (0.0433744); expected 510.9 (0.02) Passed bias filter: 861 (0.0337052); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1245.63 // Query: FUN_000511-T1 [L=677] Description: FUN_000511 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-23 83.7 0.0 4e-23 82.7 0.0 1.5 1 TIR_2 TIR domain 7.3e-07 29.4 1.3 0.029 14.3 0.1 2.6 3 ARM_PUB Plant U-box protein ARM repeat region 4.6e-05 23.4 0.5 0.21 11.4 0.0 2.6 3 ARM_ARMC5 ARMC5 0.00029 21.2 0.6 0.00066 20.0 0.0 1.8 2 TIR TIR domain 0.00053 20.4 0.0 1.1 9.9 0.0 4.2 5 Arm Armadillo/beta-catenin-like repeat ------ inclusion threshold ------ 0.022 14.8 0.1 2.4 8.1 0.0 2.4 2 Arm_2 Armadillo-like 0.067 14.1 0.0 0.16 12.9 0.0 1.6 1 SAM_1 SAM domain (Sterile alpha motif) 0.1 13.4 0.1 16 6.3 0.0 3.3 3 HEAT_2 HEAT repeats 0.14 12.8 0.0 0.56 10.9 0.0 2.1 1 SAM_2 SAM domain (Sterile alpha motif) 0.17 12.6 0.0 0.41 11.4 0.0 1.6 1 SEFIR SEFIR domain Domain annotation for each model (and alignments): >> TIR_2 TIR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.7 0.0 1.6e-26 4e-23 1 121 [. 454 571 .. 454 572 .. 0.89 Alignments for each domain: == domain 1 score: 82.7 bits; conditional E-value: 1.6e-26 TIR_2 1 VfiSYagedrewaewladaLeaagirvwldewdikpgddwveeieeaieesdrvvavlspaylesewcqeEleaalaadeegrkrliPvlleeele 96 V+iSY+++ +e + +l+++Le++g+rvw+d +++ +++ e++++aie+s+ +++ +s++y +s++c+ E e+a++ +rk +iP+++ee + FUN_000511-T1 454 VMISYQWDTQETMLRLKTELESKGLRVWMDVEQM--KGSILETMARAIEKSSLILIAMSRKYQNSPNCRSEAEYAYQ----RRKQIIPLMMEE-SY 542 89*****************************865..889*************************************8....6677*******5.55 PP TIR_2 97 kp.e.l....adlqyidlrkgdedeaalerL 121 +p + l +++ + d+rk+ ++++++L FUN_000511-T1 543 SPdGwLgiilGSKLWMDFRKE--PHKGIQQL 571 6742345677*********54..66888888 PP >> ARM_PUB Plant U-box protein ARM repeat region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 2.9 7.5e+03 120 161 .. 147 189 .. 137 194 .. 0.50 2 ! 13.5 0.0 2e-05 0.051 60 146 .. 244 332 .. 196 351 .. 0.82 3 ! 14.3 0.1 1.1e-05 0.029 30 130 .. 354 450 .. 346 457 .. 0.82 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 2.9 ARM_PUB 120 eaesklsiaksegvleevmklikdkis.rsavkaalsiliais 161 ++ +kl + +++ + ++ +++ + +s vk al+++++is FUN_000511-T1 147 VDVPKLLTDVLRSLHQKYPNVFSSEGQaNSEVKWALEVIYSIS 189 4444444444444444444444444444556666666666666 PP == domain 2 score: 13.5 bits; conditional E-value: 2e-05 ARM_PUB 60 d....sselvsealalLvllk.pitdeeklklkdpdsvellvkllkrgsveskinaaallkelleeaesklsiaksegvleevmklikdkis 146 d +l+ e+l +L+ l i++++ ++ d ve+l+ +++ + + a + l l+ e++ +l++a +e +++++kl+++ + FUN_000511-T1 244 DryskTGSLGFEVLGVLHNLSkSINNKKY--FDSSDAVETLLSFFRTKFPSYRLTALLCLAYLVDEKNNHLIMATEEP-IKDILKLLEKACN 332 24445788999**********55555555..589999**********************************9998776.5899999998766 PP == domain 3 score: 14.3 bits; conditional E-value: 1.1e-05 ARM_PUB 30 keseknrkllaekgvvelLvdilskfsededsselvsealalLvllkpitdeeklklkdpdsvellvkllkrgsveskinaaallkelleeaeskl 125 + ++ n+k++ + g+ +lL+ +l+ +++ +e a++ L++l ++++++ ++d ++ ll l ++g+ e+k+ a+ ++ e+ ++e + FUN_000511-T1 354 ATNDGNKKTIGQLGGISLLATMLKGETD---LRE-RLAAVKALYMLSFDEENKAIIKADIGIMDLLQSLHNSGEKEIKQAASGVIWEIEGKKEANI 445 56788********************996...333.33588999999944555666699******************************98887777 PP ARM_PUB 126 siaks 130 + s FUN_000511-T1 446 KTCDS 450 55544 PP >> ARM_ARMC5 ARMC5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 3 7.6e+03 185 207 .. 199 221 .. 180 228 .. 0.68 2 ! 9.3 0.0 0.00037 0.93 51 128 .. 259 335 .. 256 351 .. 0.88 3 ! 11.4 0.0 8e-05 0.21 55 139 .. 353 437 .. 347 476 .. 0.71 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 3 ARM_ARMC5 185 qsevRpaLGnagaiellieelkk 207 + +++ a G+ag++e ++++++ FUN_000511-T1 199 HRKFCEACGEAGLVEECLKLMRS 221 55666777888888877776665 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00037 ARM_ARMC5 51 ligNLAedkenaealheagvvpalvellketedsetlqmavRalriLwdtkekreeilesgavravaellsseeeeal 128 ++ NL+++ +n + + ++++v++l+++ ++ + + +++a+ l +L d k+++ + ++ ++ + +ll++++++a FUN_000511-T1 259 VLHNLSKSINNKKYFDSSDAVETLLSFFRT-KFPSYRLTALLCLAYLVDEKNNHLIMATEEPIKDILKLLEKACNSAD 335 577**********************99987.5556999**********************************998764 PP == domain 3 score: 11.4 bits; conditional E-value: 8e-05 ARM_ARMC5 55 LAedkenaealheagvvpalvellketedsetlqmavRalriLwdtkekreeilesgavravaellsseeeealvkavlkalael 139 A+++ n + + + g ++ l ++lk ++d + ++ av+al +L+ +e++ i + ++ + + l ++ e+++++a+ + e+ FUN_000511-T1 353 VATNDGNKKTIGQLGGISLLATMLKGETDLRERLAAVKALYMLSFDEENKAIIKADIGIMDLLQSLHNSGEKEIKQAASGVIWEI 437 5666677777777777777778888877777778888887777666666655556666777777777777777777766655555 PP >> TIR TIR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 2.6e-07 0.00066 18 86 .. 466 532 .. 457 539 .. 0.87 2 ? -2.9 0.1 2.7 7e+03 122 144 .. 598 623 .. 595 632 .. 0.64 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 2.6e-07 TIR 18 vshllkelkqkgiklfiddrdlepGeaiadelksaIeeSrravvvlSknyasskwcleElekilecake 86 ++ l +el+ kg ++ +d + +G i +++ +aIe+S +++ +S++y +s+ c +E e++ +++k+ FUN_000511-T1 466 MLRLKTELESKGLRVWMD-VEQMKGS-ILETMARAIEKSSLILIAMSRKYQNSPNCRSEAEYAYQRRKQ 532 56789999*********9.6656665.569*********************************998875 PP == domain 2 score: -2.9 bits; conditional E-value: 2.7 TIR 122 keekvlkWrealtevan.....Gehsks 144 +++vl+W+++ +va G++ ++ FUN_000511-T1 598 AKKRVLSWQKE--DVARwlnsiGFDACE 623 46799999977..888766645554444 PP >> Arm Armadillo/beta-catenin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 5.2 1.3e+04 8 23 .. 206 221 .. 204 223 .. 0.80 2 ? -2.8 0.0 4.5 1.1e+04 31 40 .. 255 264 .. 254 265 .. 0.85 3 ? 3.7 0.0 0.039 99 4 40 .. 269 305 .. 266 306 .. 0.88 4 ! 9.9 0.0 0.00044 1.1 1 27 [. 356 383 .. 356 395 .. 0.83 5 ? 1.0 0.0 0.27 7e+02 17 39 .. 414 437 .. 411 437 .. 0.84 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 5.2 Arm 8 vieaGavppLvrLLss 23 eaG v+ ++L++s FUN_000511-T1 206 CGEAGLVEECLKLMRS 221 5689999999999987 PP == domain 2 score: -2.8 bits; conditional E-value: 4.5 Arm 31 eAawALsNLa 40 e+++ L NL+ FUN_000511-T1 255 EVLGVLHNLS 264 7899*****8 PP == domain 3 score: 3.7 bits; conditional E-value: 0.039 Arm 4 nkqavieaGavppLvrLLsspdeevqeeAawALsNLa 40 nk++ ++ av+ L+++ +++ ++ + A+ +L++L+ FUN_000511-T1 269 NKKYFDSSDAVETLLSFFRTKFPSYRLTALLCLAYLV 305 5566667899*************************97 PP == domain 4 score: 9.9 bits; conditional E-value: 0.00044 Arm 1 spenkqavieaGavppLvrLLs.spdee 27 ++ nk+++ ++G++ L ++L+ +d + FUN_000511-T1 356 NDGNKKTIGQLGGISLLATMLKgETDLR 383 789*******************877766 PP == domain 5 score: 1.0 bits; conditional E-value: 0.27 Arm 17 LvrLLs.spdeevqeeAawALsNL 39 L++ L+ s+ e++++A + ++ + FUN_000511-T1 414 LLQSLHnSGEKEIKQAASGVIWEI 437 5566779*************9976 PP >> Arm_2 Armadillo-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.1 0.013 34 143 196 .. 253 306 .. 248 327 .. 0.85 2 ? 8.1 0.0 0.00095 2.4 33 87 .. 354 409 .. 321 421 .. 0.83 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.013 Arm_2 143 kvqvLkvllnlseNpamtrellsakvlssllslfnkkeakeillrvltifenik 196 ++vL vl nls+ ++ + + s + +lls f k + l +l ++ + FUN_000511-T1 253 GFEVLGVLHNLSKSINNKKYFDSSDAVETLLSFFRTKFPSYRLTALLCLAYLVD 306 589********************************9999999988888877665 PP == domain 2 score: 8.1 bits; conditional E-value: 0.00095 Arm_2 33 aaysvnqdiirdlggitiianlls.ksnaevkekalnalnnlsenvenqkkikvyv 87 a n+++i +lggi ++a +l +++ +++ a+ al ls + en+ ik+ + FUN_000511-T1 354 ATNDGNKKTIGQLGGISLLATMLKgETDLRERLAAVKALYMLSFDEENKAIIKADI 409 55556999***************8357778888***************99888755 PP >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 6.2e-05 0.16 3 33 .. 605 634 .. 603 641 .. 0.81 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 6.2e-05 SAM_1 3 wsvedVgeWLesiglgqYadsFrkgyidget 33 w +edV++WL+sig+ ++++ r+ dg FUN_000511-T1 605 WQKEDVARWLNSIGFDACENEVRSKL-DGGL 634 99*************99999996655.6655 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.0063 16 26 58 .. 272 304 .. 263 343 .. 0.75 2 ? 2.0 0.2 0.14 3.5e+02 33 58 .. 369 395 .. 321 407 .. 0.75 3 ? -0.1 0.0 0.64 1.6e+03 3 27 .. 413 437 .. 411 445 .. 0.81 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0063 HEAT_2 26 eigdpealpaLlellkdedpavRraaakaLgki 58 ++++++a+++Ll++ +++ p R +a+ +L+ + FUN_000511-T1 272 YFDSSDAVETLLSFFRTKFPSYRLTALLCLAYL 304 678999*********************999844 PP == domain 2 score: 2.0 bits; conditional E-value: 0.14 HEAT_2 33 lpaLlell.kdedpavRraaakaLgki 58 +++L +l + +d + R aa+kaL + FUN_000511-T1 369 ISLLATMLkGETDLRERLAAVKALYML 395 566777775567777777777777665 PP == domain 3 score: -0.1 bits; conditional E-value: 0.64 HEAT_2 3 aLlqaLlkdpdpevraaairaLgei 27 Llq L+++ ++e+++aa ++ ei FUN_000511-T1 413 DLLQSLHNSGEKEIKQAASGVIWEI 437 69999999******99998888776 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00022 0.56 1 24 [. 602 625 .. 602 634 .. 0.87 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00022 SAM_2 1 veswslesvaeWLrsigleqykdn 24 v sw e+va+WL sig+ +++ FUN_000511-T1 602 VLSWQKEDVARWLNSIGFDACENE 625 568***************998876 PP >> SEFIR SEFIR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00016 0.41 2 76 .. 453 515 .. 452 547 .. 0.82 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00016 SEFIR 2 kvfivYssdselhtevVlklaefLqdlcglevalDlwekkeiaeegqvkWlerqiqeadkviivlskgakekvkk 76 v+i+Y +d+++ l+l L++ gl+v +D + + + ++ + r+i++++ ++i +s+ ++ FUN_000511-T1 453 HVMISYQWDTQET---MLRLKTELESK-GLRVWMDVEQM----KGSILETMARAIEKSSLILIAMSRKY----QN 515 69********999...9**********.********999....7799*****************99433....32 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (677 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1270 (0.0497162); expected 510.9 (0.02) Passed bias filter: 993 (0.0388726); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.41u 0.42s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 6389.56 // Query: FUN_000512-T1 [L=317] Description: FUN_000512 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-22 79.7 16.9 2.1e-11 44.3 5.0 2.2 2 7tm_1 7 transmembrane receptor (rhodopsin family) 4.2e-06 26.8 13.5 3.3e-05 23.9 13.5 2.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.061 13.9 0.3 0.061 13.9 0.3 2.2 3 UPF0242 Uncharacterised protein family (UPF0242) N-ter 0.93 10.2 7.2 15 6.3 0.2 3.3 3 Sid-5 Sid-5 family 1.9 8.8 5.7 0.36 11.1 0.4 2.4 2 DUF3487 Protein of unknown function (DUF3487) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.0 4.3 4e-14 2e-10 2 118 .. 50 169 .. 49 174 .. 0.87 2 ! 44.3 5.0 4.2e-15 2.1e-11 157 260 .] 179 287 .. 172 287 .. 0.83 Alignments for each domain: == domain 1 score: 41.0 bits; conditional E-value: 4e-14 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevl....CklvtaldvvnltasillltaisiDRYlaIvkplky 93 N+lVil++ ++ +l++ +ni+l La +D ++l++ p +++ +l + +++++ + + ++ +t s+l+l++++++R +aI + FUN_000512-T1 50 NILVILAVKKTPRLQSKANILLACLAATDAFIGLTAQPSSVLDEL-FRLIDMKSLAliirDYIHSGALLAGMTNSLLHLMLVTFERLVAIKFTTDH 144 9*******************************************9.3555555554222344555566788999********************** PP xxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllsl 118 + ++t + ++ ++++W++al+++ FUN_000512-T1 145 PFLMTEKNIKISVAIFWIIALCIWA 169 *********************9976 PP == domain 2 score: 44.3 bits; conditional E-value: 4.2e-15 xxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 157 lsvlgfllpl..lvilvcyvrilrtlrksakkeks.....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallit 245 ++++g l+p ++i+++yv +r+ +++k+ k+ ++ +++ ke+kalkt + vv+ vlc++P i++l ++ e s +++ +l+++ FUN_000512-T1 179 VFTVGPLVPSciIFITISYVILYRETLRHRKRIKTeqipqQEVEMFLKENKALKTAVYVVGSLVLCFIPSSIVFLSYVV--EGLSLNNSVYFLSFS 272 455666666511557889********999999998666666777777888**********************9999999..777888888899*** PP xxxxxxxxxxxxxxx RF 7tm_1 246 lllayvnsclNPiiY 260 ++l+++ns+lNP+iY FUN_000512-T1 273 RVLMMLNSLLNPLIY 287 *************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 13.5 6.5e-09 3.3e-05 4 252 .. 46 297 .. 43 300 .. 0.80 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 6.5e-09 7TM_GPCR_Srsx 4 GliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvl..lltgtqlkreeCF...lliivyvfgltaqsvllLv.igiDlliavkfP 93 + N+l+il++ k+++L+sk +iL+ +++ d ++ + ++ vl l++ + +k+ ++ + ++++ ++ s+l L+ +++ +l+a+kf+ FUN_000512-T1 46 TILLNILVILAVKKTPRLQSKANILLACLAATDAFIGLTAQPSSVLdeLFRLIDMKSLALIirdYIHSGALLAGMTNSLLHLMlVTFERLVAIKFT 141 56779******************************9999888888522565555555443311134455667777777777761569********* PP 7TM_GPCR_Srsx 94 irYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek........kkss 181 + + l +ek + i +++ + +++i +++ Ca+p+a+ ++ + +++i ++ +++y + + k+ k++ + FUN_000512-T1 142 TDHPFLMTEKNIKISVAIFWIIALCI-----------WALRCAAPFAMVFTVGPLVPSCIIFITISYVILYRETLRHRKRIKTEqipqqeveMFLK 226 *********98888777666666655...........4578******************************9999986666655576664444445 PP 7TM_GPCR_Srsx 182 skkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrka 252 +k lk ++v +++ + s+i++ + s +++ + + +l++l++ n ++ wr +e rk FUN_000512-T1 227 ENKALKTAVYVVGSLVLCFIPSSIVFLSYVVEGLSLNNSVYFLSFSRVLMMLNSLLNPLIYFWRDKEMRKL 297 566777777777778***********9999999999***99**************************9985 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 0.83 4.2e+03 37 65 .. 113 140 .. 94 158 .. 0.65 2 ? -1.3 0.1 0.52 2.7e+03 35 68 .. 179 214 .. 135 233 .. 0.57 3 ? 13.9 0.3 1.2e-05 0.061 3 65 .. 236 297 .. 234 311 .. 0.87 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.83 UPF0242 37 siglllaaagslllllllkqwekalkekf 65 s +ll sll+l+l+ +e kf FUN_000512-T1 113 SGALLAGMTNSLLHLMLV-TFERLVAIKF 140 556666777888777665.5666666666 PP == domain 2 score: -1.3 bits; conditional E-value: 0.52 UPF0242 35 llsiglllaaagslllllllkqwekalkekf..eks 68 ++++g l+ ++ + ++ + + ++l+++ + + FUN_000512-T1 179 VFTVGPLVPSCIIFITISYVILYRETLRHRKriKTE 214 666666666666666655555554444433222222 PP == domain 3 score: 13.9 bits; conditional E-value: 1.2e-05 UPF0242 3 qlsisaiflYllpllvlsiysiqllseqksWtllsiglllaaagslllllllkqwekalkekf 65 ++++s ++ ++++ +v+ +y + ls+++s ++ls+ + l+ sl l l++ w + + k+ FUN_000512-T1 236 YVVGSLVLCFIPSSIVFLSYVVEGLSLNNSVYFLSFSRVLMMLNSL-LNPLIYFWRDKEMRKL 297 678999****************************************.6689999998887776 PP >> Sid-5 Sid-5 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.2 0.43 2.2e+03 24 37 .. 44 57 .. 28 63 .. 0.73 2 ? 6.2 0.1 0.0032 16 27 57 .. 190 220 .. 184 226 .. 0.87 3 ? 6.3 0.2 0.0029 15 14 43 .. 263 294 .. 260 303 .. 0.81 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.43 Sid-5 24 illlllNilqvvff 37 + +llNil ++ + FUN_000512-T1 44 PFTILLNILVILAV 57 46788888887755 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0032 Sid-5 27 lllNilqvvffnRakllklyRrrfqqlPese 57 +++ ++ v+++R++l + R + +q+P++e FUN_000512-T1 190 IIFITISYVILYRETLRHRKRIKTEQIPQQE 220 5666778899*******************99 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0029 Sid-5 14 encvilLaisilllllN..ilqvvffnRakll 43 +n v+ L +s +l++lN + +++f R k + FUN_000512-T1 263 NNSVYFLSFSRVLMMLNslLNPLIYFWRDKEM 294 689**************433469999998754 PP >> DUF3487 Protein of unknown function (DUF3487) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.4 0.48 2.5e+03 44 67 .. 31 53 .. 21 65 .. 0.52 2 ? 11.1 0.4 7.1e-05 0.36 30 101 .. 162 235 .. 148 245 .. 0.75 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.48 DUF3487 44 alllgaiamvptlavvavllvvvv 67 al+++ i++ t+ ++ll ++v FUN_000512-T1 31 ALVIQ-IIITTTACPFTILLNILV 53 33333.444444444444444433 PP == domain 2 score: 11.1 bits; conditional E-value: 7.1e-05 DUF3487 30 glgivvg.lvlglllalllgaiamvptlavvavllvvvvggtllrrlkRGrPetylyrrlevkla.rlllgekr 101 +++ ++ l ++ + a+++ +vp++++ + v++ ++lr kR + e+ ++++e+ l+ l+ FUN_000512-T1 162 IIALCIWaLRCAAPFAMVFTVGPLVPSCIIFITISYVILYRETLRHRKRIKTEQIPQQEVEMFLKeNKALKTAV 235 34455551345677888888889999999999999999999*****************9999888434444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1240 (0.0485418); expected 510.9 (0.02) Passed bias filter: 583 (0.0228225); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3088.91 // Query: FUN_000513-T1 [L=108] Description: FUN_000513 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (108 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 570 (0.0223136); expected 510.9 (0.02) Passed bias filter: 370 (0.0144842); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1087.15 // Query: FUN_000514-T1 [L=325] Description: FUN_000514 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-21 77.3 21.8 1.3e-11 44.9 7.0 2.2 2 7tm_1 7 transmembrane receptor (rhodopsin family) 0.00075 19.7 8.7 0.00075 19.7 8.7 2.4 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx ------ inclusion threshold ------ 0.54 10.8 4.5 0.83 10.2 1.0 2.2 2 UPF0242 Uncharacterised protein family (UPF0242) N-term 4.3 7.3 11.6 2.7 7.9 1.1 2.7 3 YhfC YhfC intramembrane metalloprotease Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 7.4 2.7e-13 1.7e-09 2 116 .. 52 169 .. 51 176 .. 0.87 2 ! 44.9 7.0 2.1e-15 1.3e-11 155 260 .] 179 289 .. 169 289 .. 0.80 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 2.7e-13 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvll...lvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkyk 94 N+lVil++ ++++l++ ni+l La +D ++l + + ++ ++ + + +++ + +++ +t s+l+l++++++R +aI ++y+ FUN_000514-T1 52 NILVILAVKKTRRLQSKPNILLACLAATDAFIGLtvqSSYILFATFQVSGMNSLAQAIRFHWHDRAILAGVTNSLLHLMLVTFERLVAIKFTIHYP 147 9********************************7443333444455555666666777799999999***************************** PP xxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 95 rirtkrralvlilvvWvlalll 116 + t + +v ++++W++ ++ FUN_000514-T1 148 FLITEKNIKVSVVIFWIITFCS 169 ******************9986 PP == domain 2 score: 44.9 bits; conditional E-value: 2.1e-15 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 155 lllsvlgfllp..llvilvcyvrilrtlrksakkekskkkksarker.....kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetall 243 + ++++g l+p +++i+++yv +r+ +++k+ k+++ +++ e+ kalkt++ vv+ vlc++P ++l++ ++ +++s ++ +++ FUN_000514-T1 179 VAAFTVGPLVPscMIFIAISYVILYRETLRHKKRIKTEQIAQQEVETflkenKALKTTVYVVGSLVLCFIPSLLLFVSLAV--KSPSLVTSVYFVS 272 5666777777522677899***************999555554444456666**********************9999998..566666666777* PP xxxxxxxxxxxxxxxxx RF 7tm_1 244 itlllayvnsclNPiiY 260 +++++a++ns+lNP+iY FUN_000514-T1 273 FCRMFAMLNSLLNPLIY 289 ***************** PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 8.7 1.2e-07 0.00075 8 125 .. 49 169 .. 44 177 .. 0.88 2 ? -1.2 2.9 0.27 1.7e+03 179 234 .. 195 252 .. 173 279 .. 0.59 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 1.2e-07 7TM_GPCR_Srx 8 lvlNllvliailklkslknsFgilclskaisnaiilli...flfyvvPmtllqsellkellnshliglialglYeisplsqllialNRfcavffpl 100 ++lN+lv++a+ k+ +l++ +il ++ a +a i l+ ++++ ++++ + l + + h+ + l s l +l++++R++a+ f++ FUN_000514-T1 49 ILLNILVILAVKKTRRLQSKPNILLACLAATDAFIGLTvqsSYILFATFQVSGMNSLAQAIRFHWHDRAILAGVTNSLLHLMLVTFERLVAIKFTI 144 689*****************************998776344567788889999999999999999999888888888888899************* PP 7TM_GPCR_Srx 101 kyekifsiknTkiiiviiwivslif 125 +y + + kn k+++vi+wi++++ FUN_000514-T1 145 HYPFLITEKNIKVSVVIFWIITFCS 169 *********************9984 PP == domain 2 score: -1.2 bits; conditional E-value: 0.27 7TM_GPCR_Srx 179 ltaiklilskkkskstsseeskrrrkreinffkQ..svlQdllflidlvnyfliaplv 234 ++++ +il++ + ++ + ++++ ++e+ f+ + l ++++++++ ++i++l+ FUN_000514-T1 195 IAISYVILYRETLRHKKRIKTEQIAQQEVETFLKenKALKTTVYVVGSLVLCFIPSLL 252 3333333444444444444455555555554443125677777777777777777654 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.1 0.05 3.2e+02 18 80 .. 164 230 .. 154 238 .. 0.66 2 ? 10.2 1.0 0.00013 0.83 3 69 .. 238 303 .. 236 317 .. 0.85 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.05 UPF0242 18 vlsiysiqllseqksWtllsiglllaaagslllllllkqwekalkekf....eksfleekealltee 80 ++++ s++l + +++g l+ ++ ++++ + + ++l++k e++ +e e +l e+ FUN_000514-T1 164 IITFCSWPLRYITPYVAAFTVGPLVPSCMIFIAISYVILYRETLRHKKriktEQIAQQEVETFLKEN 230 6677777766666677789999999999888888888888777766554544444444445555554 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00013 UPF0242 3 qlsisaiflYllpllvlsiysiqllseqksWtllsiglllaaagslllllllkqwekalkekfeksf 69 ++++s ++ ++++ll++++ ++ s+ s ++ s+ ++ a sl l l++ w + + + + FUN_000514-T1 238 YVVGSLVLCFIPSLLLFVSLAVKSPSLVTSVYFVSFCRMFAMLNSL-LNPLIYFWRDKEMRSVQIQT 303 68899*************9999999999******************.66789999887777666554 PP >> YhfC YhfC intramembrane metalloprotease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.9 0.0017 11 138 190 .. 12 67 .. 2 79 .. 0.76 2 ? 7.9 1.1 0.00042 2.7 109 179 .. 81 151 .. 77 170 .. 0.79 3 ? -1.9 0.1 0.42 2.7e+03 11 35 .. 225 249 .. 218 285 .. 0.66 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0017 YhfC 138 paglaeliqkqleslsllsivlgvlERilalv...vqialsvlvlyavrqkkvifl 190 ++++ +i + ++l l + v+ ++ i++ + + i+l +lv++av++ +++ FUN_000514-T1 12 LKQFSRNISDEGLQLQLPEQVVLIIQIIITTAtcpLTILLNILVILAVKKTRRLQS 67 4788888888888888888888888888766533379************9988755 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00042 YhfC 109 illgvlslvnlivlaslinsgeleallslpaglaeliqkqleslsllsivlgvlERilalvvqialsvlvl 179 +++g+ ++ + i++a+ sg + + + + + sll+++l +ER++a+ + i l+ FUN_000514-T1 81 AFIGLTVQSSYILFATFQVSGMNSLAQAIRFHWHDRAILAGVTNSLLHLMLVTFERLVAIKFTIHYPFLIT 151 6899999999999998888887665566677777777778888999*****************99888775 PP == domain 3 score: -1.9 bits; conditional E-value: 0.42 YhfC 11 vylkkkyqlslkvlllGavvfavfa 35 +lk +l+ v ++G +v FUN_000514-T1 225 TFLKENKALKTTVYVVGSLVLCFIP 249 5777777777777777776644333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (325 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1512 (0.0591897); expected 510.9 (0.02) Passed bias filter: 723 (0.028303); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3202.24 // Query: FUN_000515-T1 [L=315] Description: FUN_000515 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-21 75.4 24.4 4.6e-11 43.2 9.9 2.2 2 7tm_1 7 transmembrane receptor (rhodopsin family) 8.6e-05 22.5 25.0 0.0016 18.4 25.0 2.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 3.9 8.7 6.0 1.5 10.0 0.8 2.8 3 EphA2_TM Ephrin type-A receptor 2 transmembrane domain Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.7 7.4 2.6e-13 2.2e-09 2 121 .. 52 174 .. 51 179 .. 0.92 2 ! 43.2 9.9 5.4e-15 4.6e-11 152 260 .] 178 290 .. 173 290 .. 0.83 Alignments for each domain: == domain 1 score: 37.7 bits; conditional E-value: 2.6e-13 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal...legdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkyk 94 N+lVil++ ++++l++ ni+l La +D ++l++ p +++ ++ + + +++ ++ + + ++ +t s+l+l++++++R ++I ++ + FUN_000515-T1 52 NILVILAVKKTRRLQSKPNILLACLAATDAFIGLTAQPSSILVEVfrlIDMTSLAQKIRLNFHNRVLLAGITNSLLHLMLVTFERLVVIKFTVHHP 147 9*********************************9999999777633356777888999999********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 95 rirtkrralvlilvvWvlalllslppl 121 + t + ++ ++ +W++al++ + + FUN_000515-T1 148 FLITEKYIKISVATFWIIALCILALRY 174 ********************9987765 PP == domain 2 score: 43.2 bits; conditional E-value: 5.4e-15 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 152 sytlllsvlgfllpllvilvcyvrilrtlrksakkekskkkksarker.....kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetal 242 +++l++ + +++ +++i+++yv +r+ +++k+ k+++ ++++ e+ kalkt++ vv+ vlc++P ++ll+ ++ k + ++ ++ FUN_000515-T1 178 YVVLFTAASLMVICVIFIAISYVILYRETLRHKKRIKTEQVSQQEVETflkenKALKTTVYVVGSLVLCFTPSLFLLVSIVV-KRLSLVANSVSFV 272 45666667777779********************9999444443333366666*******************9987666665.8888999999999 PP xxxxxxxxxxxxxxxxxx RF 7tm_1 243 litlllayvnsclNPiiY 260 +++++l ++ns+lNP+iY FUN_000515-T1 273 SFCRVLVMLNSLLNPLIY 290 ****************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 25.0 1.9e-07 0.0016 4 252 .. 48 300 .. 45 303 .. 0.74 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 1.9e-07 7TM_GPCR_Srsx 4 GliGNvllilltfkkkkLrskssiLicvqcladllclvge.....lvfvvllltgtqlkreeCFlliivyvfgltaqsvllLvi.giDlliavkfP 93 + N+l+il++ k+++L+sk +iL+ +++ d ++ + lv+v+ l+++t+l ++ + +++ ++ s+l L++ ++ +l+++kf+ FUN_000515-T1 48 TILLNILVILAVKKTRRLQSKPNILLACLAATDAFIGLTAqpssiLVEVFRLIDMTSLAQKIRLNFHNRVLLAGITNSLLHLMLvTFERLVVIKFT 143 56779****************************9986544122225666778999999**999999998899888888887775169********* PP 7TM_GPCR_Srsx 94 irYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek.....kkssskk 184 + + l +ekY+ i ++ + +++il+l ++ p ++l +a +++ + +++i+++ +++y + + k+ k++ + +++ k FUN_000515-T1 144 VHHPFLITEKYIKISVATFWIIALCILALRYII----------PYVVL-FTAASLMVICVIFIAISYVILYRETLRHKKRIKTEqvsqqEVETFLK 228 **************************9999974..........22333.45566777888889999999998887764433333333334444544 PP 7TM_GPCR_Srsx 185 vlkslkvtvvif...ifgWftst.ilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrka 252 k lk+tv ++ +++ + s +l +++++ + +++ + + + +lv+l++ n ++ wr +e rk FUN_000515-T1 229 ENKALKTTVYVVgslVLCFTPSLfLLVSIVVKRLSLVANSVSFVSFCRVLVMLNSLLNPLIYFWRDKEMRKI 300 446666666665442666554431334444555566677777889999********************9985 PP >> EphA2_TM Ephrin type-A receptor 2 transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 0.31 2.6e+03 10 25 .. 48 64 .. 38 70 .. 0.41 2 ? 10.0 0.8 0.00018 1.5 2 51 .. 184 235 .. 180 240 .. 0.67 3 ? -2.1 0.1 1.1 9.1e+03 16 16 .. 254 254 .. 235 278 .. 0.54 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.31 EphA2_TM 10 vllvvvvvvlivrr.rr 25 +l+ ++v+l+v++ rr FUN_000515-T1 48 TILLNILVILAVKKtRR 64 23333444445444133 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00018 EphA2_TM 2 vgavagglvllvvvvvvlivrr..rrkkrskaeqdyeekeeqlsvklpglkt 51 ++++++++v+++++ +v+++r r+kkr k eq ++++ e + + + lkt FUN_000515-T1 184 AASLMVICVIFIAISYVILYREtlRHKKRIKTEQVSQQEVETFLKENKALKT 235 4566666666666777777777888888888888887777777455555554 PP == domain 3 score: -2.1 bits; conditional E-value: 1.1 EphA2_TM 16 v 16 + FUN_000515-T1 254 L 254 2 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (315 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2019 (0.079037); expected 510.9 (0.02) Passed bias filter: 732 (0.0286553); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3121.83 // Query: FUN_000516-T1 [L=311] Description: FUN_000516 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-20 73.0 11.5 3.7e-12 46.8 1.1 2.2 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.1e-05 25.5 11.2 4.4e-05 23.5 11.2 1.9 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 2.9e-05 24.3 6.7 2.9e-05 24.3 6.7 2.0 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx ------ inclusion threshold ------ 0.016 15.6 0.3 0.054 13.8 0.1 1.8 2 TMEM154 TMEM154 protein family 0.63 10.0 3.9 0.24 11.3 0.2 2.0 2 DUF6161 Family of unknown function (DUF6161) 3.2 9.2 4.7 8 7.9 4.6 2.0 1 PLAC8 PLAC8 family Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 5.6 1.2e-10 5.2e-07 2 123 .. 49 173 .. 48 188 .. 0.85 2 ! 46.8 1.1 8.6e-16 3.7e-12 158 260 .] 179 286 .. 170 286 .. 0.78 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 1.2e-10 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfal...vyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkyk 94 N+ Vil++ ++ +l++ ni+l La +D +++++ p + + ++ + + + +++ + v+ + s+l+l++++++R +aI + y+ FUN_000516-T1 49 NISVILAVKKTPRLQSKPNILLACLAATDAFIGITAQPSYIlfaAFQVFGINSQAQSIRSHWHDRALVAGMSNSLLHLMLVTLERLIAIKFTICYP 144 99*******************************977665541113334467778888888999999****************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 95 rirtkrralvlilvvWvlalllslppllf 123 i t + ++ ++ +W++al + + ++ FUN_000516-T1 145 YIITEKNIKISVVSFWTMALSTWGMGYMT 173 *******************9877666655 PP == domain 2 score: 46.8 bits; conditional E-value: 8.6e-16 xxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 158 svlgfll..pllvilvcyvrilrtlrksakkekskkkksarker.....kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitl 246 ++ g l+ l++i++cyv +r+ +++++ k ++ +++ e+ kalkt++ vv+ +lc+lP f+++l + ++ + ++ ++ +++ FUN_000516-T1 179 FTAGPLIacCLIFIAICYVILYRETLRHKERIKAEQVAQQEVEHflkenKALKTTVYVVGSLALCFLPAFLVILSVKV--DSLTLEKSDDIVGWSR 272 33333332378999*************9999998444443333355555**********************8887777..66677778888999** PP xxxxxxxxxxxxxx RF 7tm_1 247 llayvnsclNPiiY 260 l++++ns+lNP+iY FUN_000516-T1 273 LFTMLNSLLNPLIY 286 ************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 11.2 1e-08 4.4e-05 4 256 .. 45 300 .. 42 301 .. 0.68 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 1e-08 7TM_GPCR_Srsx 4 GliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv.....llltgtqlkre.eCFlliivyvfgltaqsvl.lLvigiDlliavkf 92 + N+ +il++ k+++L+sk +iL+ +++ d ++ + ++ + + + ++ ++ + ++++ + s+l l+++++ +lia+kf FUN_000516-T1 45 TILLNISVILAVKKTPRLQSKPNILLACLAATDAFIGITAQPSYIlfaafQVFGINSQAQSiRSHWHDR-ALVAGMSNSLLhLMLVTLERLIAIKF 139 56679*****************************99887655443110014453333333313344444.44555555555145567********* PP 7TM_GPCR_Srsx 93 PirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliii.....lkkkkekkksssk 183 +i Y ++ +ek + i ++ +++++ +g+ +++++++++ a pl ++ ++i++ +++y + + +++ +++ +++ FUN_000516-T1 140 TICYPYIITEKNIKI--SVVSFWTMALSTWGMGYMTHHVVLFTAGPL---------IACCLIFIAICYVILYRETLRHkerikAEQVAQQEVEHFL 224 **********86655..566778888889999999999888765555.........5577778888888888777665343335556666788888 PP 7TM_GPCR_Srsx 184 kvlkslkvtvvif..ifgWftstilntvllalte.seevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 k k lk+tv ++ + f+ l ++++++++ + e + i ++++l++ n ++ wr +e rk + +l FUN_000516-T1 225 KENKALKTTVYVVgsLALCFLPAFLVILSVKVDSlTLEKSDDIVGWSRLFTMLNSLLNPLIYFWRDKEMRKLVSNL 300 888889999887633222233333333444333314455566788888999999999999********99988776 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 6.7 6.8e-09 2.9e-05 8 126 .. 46 167 .. 39 181 .. 0.92 2 ? 0.2 0.4 0.16 6.6e+02 175 230 .. 188 245 .. 170 261 .. 0.50 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 6.8e-09 7TM_GPCR_Srx 8 lvlNllvliailklkslknsFgilclskaisnaiilli...flfyvvPmtllqsellkellnshliglialglYeisplsqllialNRfcavffpl 100 ++lN++v++a+ k+++l++ +il ++ a +a i ++ ++++ ++++++ + + sh+ +++ ++ s l +l++l+R++a+ f++ FUN_000516-T1 46 ILLNISVILAVKKTPRLQSKPNILLACLAATDAFIGITaqpSYILFAAFQVFGINSQAQSIRSHWHDRALVAGMSNSLLHLMLVTLERLIAIKFTI 141 799*****************************9998775667899999************************************************ PP 7TM_GPCR_Srx 101 kyekifsiknTkiiiviiwivslifi 126 y i + kn ki++v +w+++l FUN_000516-T1 142 CYPYIITEKNIKISVVSFWTMALSTW 167 *********************99854 PP == domain 2 score: 0.2 bits; conditional E-value: 0.16 7TM_GPCR_Srx 175 vlnlltaiklilskkkskstsseeskrrrkreinffkQ..svlQdllflidlvnyfli 230 +l +++++ +il++ + ++ + + ++ ++e+ f+ + l ++++++++ +++ FUN_000516-T1 188 CLIFIAICYVILYRETLRHKERIKAEQVAQQEVEHFLKenKALKTTVYVVGSLALCFL 245 2223333333333333333333333444444444443211355566666665555555 PP >> TMEM154 TMEM154 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 0.52 2.2e+03 73 90 .. 44 61 .. 11 67 .. 0.69 2 ? 13.8 0.1 1.3e-05 0.054 63 108 .. 176 219 .. 173 235 .. 0.72 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.52 TMEM154 73 lliilllvvvilitkykr 90 +i+l ++v++ ++k r FUN_000516-T1 44 FTILLNISVILAVKKTPR 61 367777777777755444 PP == domain 2 score: 13.8 bits; conditional E-value: 1.3e-05 TMEM154 63 filmviiPlvlliilllvvvilitkykrkRaKddekseaesdalqt 108 ++l + Pl++ +++++++ +i + R K+ k ae+ a+q+ FUN_000516-T1 176 VVLFTAGPLIACCLIFIAICYVILYRETLRHKERIK--AEQVAQQE 219 5788888****************7777788888754..44444443 PP >> DUF6161 Family of unknown function (DUF6161) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.2 0.74 3.1e+03 114 151 .. 163 200 .. 138 205 .. 0.48 2 ? 11.3 0.2 5.7e-05 0.24 71 149 .. 206 281 .. 200 289 .. 0.83 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.74 DUF6161 114 svilvsaiefdfsesvinkeaavrw.slvlitlisllay 151 ++ ++ + + v+ + +++ l++i++ ++ y FUN_000516-T1 163 ALSTWGMGYMTHH-VVLFTAGPLIAcCLIFIAICYVILY 200 2222222222222.2333333333337777776665555 PP == domain 2 score: 11.3 bits; conditional E-value: 5.7e-05 DUF6161 71 ykekLkLeePakyWseraikykkrakkiilflvslavivlislsvilvsaiefdfsesvinkeaavrwslvlitlisll 149 +ke++k e+ a+ e+ k +k k +++++ sla +l + +vil+ ++ s+++ +++ +v ws ++ l sll FUN_000516-T1 206 HKERIKAEQVAQQEVEHFLKENKALKTTVYVVGSLALCFLPAFLVILSVKVD---SLTLEKSDDIVGWSRLFTMLNSLL 281 5899999999999999999999988666666667777999999999998888...45667999*******999999987 PP >> PLAC8 PLAC8 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 4.6 0.0019 8 18 81 .. 140 215 .. 38 245 .. 0.80 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0019 PLAC8 18 tlfcpcvlfgrnaerldkg.......ntscllalv........lvllll........lllllglalilscllRsklRekygiegspc 81 t++ p + +n ++ + + + + +++l+++a+++ +l+R++lR+k +i+ +++ FUN_000516-T1 140 TICYPYIITEKNIKISVVSfwtmalsT-------WgmgymthhV----VlftagpliACCLIFIAICYVILYRETLRHKERIKAEQV 215 667777777777777432334443320.......1323222331....02222344345555677789***********99987654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (311 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1338 (0.0523782); expected 510.9 (0.02) Passed bias filter: 709 (0.0277549); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3061.69 // Query: FUN_000517-T1 [L=170] Description: FUN_000517 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (170 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 665 (0.0260325); expected 510.9 (0.02) Passed bias filter: 377 (0.0147583); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.35s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1725.61 // Query: FUN_000518-T1 [L=498] Description: FUN_000518 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-193 641.5 0.0 8.1e-193 641.2 0.0 1.1 1 Catalase Catalase 7.1e-19 68.2 0.4 3.2e-18 66.1 0.1 2.1 2 Catalase-rel Catalase-related immune-responsive Domain annotation for each model (and alignments): >> Catalase Catalase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 641.2 0.0 6.3e-197 8.1e-193 1 382 [. 25 406 .. 25 407 .. 0.98 Alignments for each domain: == domain 1 score: 641.2 bits; conditional E-value: 6.3e-197 Catalase 1 ttseGapvadnqnsltagerGplllqdvhlieklahfdreripeRvvhAkGagahgefevtediskltkakllsevgkktpvfvRfStvagekgsa 96 tt Gapv+++++++tag+rGp+llqdv+++++++hfdreripeRvvhAkG ga+g+fevt+d++k++kak++++vgkktp++vRfStv+ge+gsa FUN_000518-T1 25 TTGYGAPVDTKTSTMTAGPRGPILLQDVQFLDEMSHFDRERIPERVVHAKGGGAFGYFEVTHDVTKYCKAKIFEKVGKKTPCLVRFSTVGGESGSA 120 6788******************************************************************************************** PP Catalase 97 dtaRdvrGfavkfyTeeGnwDlvgnntpvFfirDaikFpdlihaqkrepktnlkdaaafwdflslnpeslhqvtilfsdrgipksyrhmngfgvht 192 dtaRd+rGfa+kfyTeeGnwDlvgnntp+FfirD+i Fp++ih+qkr+p t+l+d+++fwdf++l+pe++hqv++lfsdrgip++y+hmng+g+ht FUN_000518-T1 121 DTARDPRGFAMKFYTEEGNWDLVGNNTPIFFIRDPILFPSFIHTQKRNPVTHLRDPDMFWDFITLRPETTHQVLFLFSDRGIPDGYQHMNGYGSHT 216 ************************************************************************************************ PP Catalase 193 fklvnaegeavyvkfhfktkqgvknltaeeaeklagkdpdyatrdLyeaiekgeypewelyvqvmteeeaeklkfnifDlTkvwpekevplrevGk 288 fklvn++g avy+kfh+kt+qg+knl++e+ eklag+dpdy++r Ly+ai++g+ p+w++y+qvmt e+aek +n+fDlTk+wp++e+pl++vGk FUN_000518-T1 217 FKLVNDKGVAVYCKFHLKTDQGIKNLSSEKGEKLAGSDPDYNNRMLYDAIANGKPPSWTMYLQVMTFEQAEKSPWNPFDLTKIWPHSEYPLITVGK 312 ************************************************************************************************ PP Catalase 289 lvLnrnpenyFaevEqvafspsnlvpGiefseDklLqgRlfsYaDtqryRlgvnyeqlpvNrp.kvkvanyqrdGamrveankgkepnYepnsle 382 +vL+rn++nyFae+Eq af+p+++vpGie+s+Dk+LqgRlfsY+Dt+++Rlg+ny qlpvN+p k++v n+qrdG +++++++g +pnY+pns++ FUN_000518-T1 313 MVLDRNASNYFAEIEQSAFNPASMVPGIEASPDKMLQGRLFSYHDTHLHRLGTNYLQLPVNCPyKTRVCNNQRDGPQTFDNQSG-RPNYYPNSFS 406 ***************************************************************988899999******966665.5******986 PP >> Catalase-rel Catalase-related immune-responsive # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.16 2e+03 31 47 .. 55 71 .. 53 73 .. 0.87 2 ! 66.1 0.1 2.5e-22 3.2e-18 3 64 .. 432 492 .. 428 493 .. 0.93 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.16 Catalase-rel 31 afelskvkdeeiqerml 47 +e+s+ ++e i er++ FUN_000518-T1 55 LDEMSHFDRERIPERVV 71 579***********998 PP == domain 2 score: 66.1 bits; conditional E-value: 2.5e-22 Catalase-rel 3 sfedhfsQagllyr.slseeererlvkniafelskvkdeeiqermlehlakvDpdlgqrVaea 64 + ed++sQa+l+++ l++e+r+rlv+nia++l++++ + q+r++++++kv+ dlg+++ + FUN_000518-T1 432 D-EDNYSQATLFWEkTLDDEARKRLVNNIAGHLKDAQ-AFLQKRAVDNFSKVHVDLGNKLSKT 492 3.6*********************************9.********************99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (498 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 626 (0.0245058); expected 510.9 (0.02) Passed bias filter: 566 (0.022157); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4837.06 // Query: FUN_000519-T1 [L=501] Description: FUN_000519 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-103 345.1 0.4 9.9e-103 344.8 0.4 1.0 1 p450 Cytochrome P450 Domain annotation for each model (and alignments): >> p450 Cytochrome P450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 344.8 0.4 3.9e-107 9.9e-103 2 447 .. 45 481 .. 44 496 .. 0.90 Alignments for each domain: == domain 1 score: 344.8 bits; conditional E-value: 3.9e-107 p450 2 pgptplplvgnllqlek.keelhsvltklqkkygpifrlklgskpvvvlsgpelvkevlikkgeefsgrpdealletlskafkgkgvlfangekwr 96 pgp++ p++gn + ++l l + kyg++f++++ ++p++++ +pe+ ke+l+k+ +++++ d+++l+ + + + +++ +g+kw+ FUN_000519-T1 45 PGPEATPVFGNTAYMIFkPNKLPTLLLEWYMKYGKVFGIYFFREPFLMVADPEMTKEILVKE--FPKFH-DRKTLADIP-KPYDRMLTVVRGQKWK 136 78999******98888777788888999999*******************************..56665.667777756.566788899999**** PP p450 97 klRrlltptltsfgklsleeiveeeardlveklrkkagesselditellskaalnvicsilFgerfdlledekfsellkaveelsellssssvqll 192 +R++ltpt+ ++++++ ++++e + l++k ++ +++ + +d +++l+ +++vi s++Fg++ ++ + e + + + ++ ++ +++ ll FUN_000519-T1 137 DIRSILTPTFSASKIKQMIPFMNEALDTLLAKTERISKTGEIVDFHRWLQSLTMEVILSTAFGVKAETQTVE-NDPITESAKKA--MAPNPVAGLL 229 *************777*************************************************9955555.55666666666..6789999*** PP p450 193 dlfpllkylptkllkklkeavkklkdlldklieerretldsakkkrrdfldalllakkekkgesklsdeelkatvlellfaGvdTtsstlswaLye 288 +l p+ l+ k++ ++ + +++ +++ ++i er + +k++r+d+l+++l+ak e+ g +k+++e+++a++l +l+aG++T+s+tl ++ y+ FUN_000519-T1 230 LLLPFANRLL-KYFPDMFNF-ERIGKVACNIIAERTKLNGHSKNHRKDMLQLMLDAK-EETGSEKIDNEDIQAQTLVFLLAGYETSSTTLGFVSYH 322 ****887777.788888878.99************999999999************8.666668******************************** PP p450 289 LaknPevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtlvivnlyalhrdpkvfpnPeeF 383 La + +vq+klr Eid+ d+++p+yd l k+ yld+vi+E+LR++p+ l+R +++ ++++g++ipkG +++++ya+hrdpk++p+Pe+F FUN_000519-T1 323 LALDTQVQDKLRDEIDRLWpDDEETPSYDVLHKMDYLDMVINEALRMYPPGF-VLQRDCNEGCTVKGVNIPKGMPIMIPVYAIHRDPKIWPEPEKF 417 *******************66677****************************.999**************************************** PP p450 384 dpeRFldekgnsrksfaflPFGaGpRnClGerlArmelklflatlLqnFevelqpetdpkdide 447 +peRF ++++++r+++ f+PFG GpRnC+G+r+A +elkl l++lL+++++e ++t +++ + FUN_000519-T1 418 NPERFTEAEKANRHPYTFMPFGYGPRNCVGMRFALLELKLTLVKLLKKYKLERTEKTAVPMEFL 481 **********88****************************************988888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (501 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 671 (0.0262674); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4910.33 // Query: FUN_000520-T1 [L=501] Description: FUN_000520 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-105 351.5 0.2 1.1e-104 351.3 0.2 1.0 1 p450 Cytochrome P450 ------ inclusion threshold ------ 0.28 11.9 0.0 0.57 10.9 0.0 1.5 1 DUF6306 Domain of unknown function (DUF6306) Domain annotation for each model (and alignments): >> p450 Cytochrome P450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 351.3 0.2 8.8e-109 1.1e-104 2 449 .. 45 483 .. 44 496 .. 0.90 Alignments for each domain: == domain 1 score: 351.3 bits; conditional E-value: 8.8e-109 p450 2 pgptplplvgnllqlek.keelhsvltklqkkygpifrlklgskpvvvlsgpelvkevlikkgeefsgrpdealletlskafkgkgvlfangekwr 96 pgp+ p++g+ l ++l + + kkyg++f++++ ++p++++ +pe++ke+l+k+ +++++ ++al + + + ++ +++ +g+kw+ FUN_000520-T1 45 PGPETTPFFGSTASLIFkPNKLPILHLDWYKKYGKVFGIYFFREPFLMVADPEMIKEILVKE--FPKFHDRKALADI-P-KPYNRMLTLVRGQKWK 136 788899999999999887666666788999********************************..5666544555554.4.577889999999**** PP p450 97 klRrlltptltsfgklsleeiveeeardlveklrkkagesselditellskaalnvicsilFgerfdlledekfsellkaveelsellssssvqll 192 +R++ltpt+ ++++++ ++++e + l++k ++ +++ + +d +++l+ +++vi s++Fg++ + ++ ++ + + ++ ++ +++ ll FUN_000520-T1 137 DIRSILTPTFSASKIKQMIPFMNEALDTLLAKAERISKTGKIVDFHRWLQSLTMEVILSTAFGVKAQ-TQTVENDPITESARKA--MAPNPVAGLL 229 *************777*************************************************99.5555555666666666..6889999*** PP p450 193 dlfpllkylptkllkklkeavkklkdlldklieerretldsakkkrrdfldalllakkekkgesklsdeelkatvlellfaGvdTtsstlswaLye 288 +l p+ l+ k++ ++ + +k+ +++ ++i er + + ++r+d+l+++l+ak e+ g +k++ e+++a++l +l+aG++T+s+tl ++ y+ FUN_000520-T1 230 LLLPFANRLL-KYFPDMFNF-EKIGKVASNIIAERTKLNGHSRNHRKDMLQLMLDAK-EETGSEKIDIEDIQAQTLVFLLAGYETSSTTLGFVSYH 322 ****887777.788888878.9*************9999999899***********8.666668******************************** PP p450 289 LaknPevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtlvivnlyalhrdpkvfpnPeeF 383 La + +vq+klr Eid+ gd+++p+yd l k+ yld+vi+E+LR++p+ l+R +++ ++++g++ipkG +++++ya+h+dp+++p+Pe+F FUN_000520-T1 323 LALDTQVQDKLRDEIDRLWpGDEETPSYDVLHKMDYLDMVINEALRMYPPGF-VLQRDCNEGCTVKGVNIPKGMPIMIPVYAIHHDPEIWPEPEKF 417 *******************9**9*****************************.999**************************************** PP p450 384 dpeRFldekgnsrksfaflPFGaGpRnClGerlArmelklflatlLqnFevelqpetdpkdideks 449 +peRF ++++++r+++ f+PFG GpRnC+G+r+A +elkl l++lL+++++e ++t +++ + FUN_000520-T1 418 NPERFTEAEKANRHPYTFMPFGYGPRNCVGMRFALLELKLTLVKLLKKYKLERTEKTAVPMEFSVG 483 **********88****************************************98888888877653 PP >> DUF6306 Domain of unknown function (DUF6306) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 4.4e-05 0.57 70 117 .. 112 159 .. 104 171 .. 0.75 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 4.4e-05 DUF6306 70 rakala.iaelferlaflnrGqawv.vrkletliprvrddelkadlkaml 117 +kala i+++++r+ l rGq w +r l+p +++k + m FUN_000520-T1 112 DRKALAdIPKPYNRMLTLVRGQKWKdIRS--ILTPTFSASKIKQMIPFMN 159 3799988*****************63554..4777777777766665555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (501 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 681 (0.0266588); expected 510.9 (0.02) Passed bias filter: 637 (0.0249364); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.42s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4837.91 // Query: FUN_000521-T1 [L=780] Description: FUN_000521 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-161 538.3 30.3 1.3e-160 535.5 30.3 2.0 1 BCCT BCCT, betaine/carnitine/choline family transporter 1.1e-08 36.4 5.8 6.3e-08 33.9 0.0 3.6 4 PLAC8 PLAC8 family ------ inclusion threshold ------ 2.9 8.3 4.5 1.6 9.1 0.9 2.5 2 DUF2721 Protein of unknown function (DUF2721) 3.5 8.1 7.5 0.4 11.1 1.2 2.7 2 DUF7942 Family of unknown function (DUF7942) Domain annotation for each model (and alignments): >> BCCT BCCT, betaine/carnitine/choline family transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 535.5 30.3 2.1e-164 1.3e-160 1 484 [. 33 556 .. 33 557 .. 0.91 Alignments for each domain: == domain 1 score: 535.5 bits; conditional E-value: 2.1e-164 BCCT 1 vflvslllillfvllglifpeeleevlntalewilekfgwlylllvllflvfvlvlafskygkikLGkddekpefstfsWlamlfaagmgiglvfw 96 v ++s++ i++fv+++ ++++++e+ ++ +++wi+++ +w+y+ ++ ++ +fv+vl fskyg++kLGk+d+kp+f ++++mlfaag+g+gl+++ FUN_000521-T1 33 VSILSAVAIWAFVIWCSVDSKRAETEMTIWMQWITRTCTWFYVGSLDVWTIFVIVLYFSKYGNMKLGKPDDKPDFGDATYFTMLFAAGIGVGLFYF 128 6799******************************************************************************************** PP BCCT 97 gvaEplshyasp.......ppgaeagteeaaeeAlaltffhwGlhawaiyalvalalayfayrkglplkissalypllgeriegliGkviDilavi 185 gvaEp++hyas+ + + + +++a+ A++lt+fhwG+haw++y++v+l la++ +rkglp++i+s+lypl+ge+i g+iG++iDil+v+ FUN_000521-T1 129 GVAEPVFHYASTtsyksgnRYYGRYNDNQRAQDAMNLTLFHWGIHAWTVYVIVGLLLAFVGFRKGLPMTIRSCLYPLVGEKIFGWIGDAIDILSVC 224 ***********95554443344477778888***************************************************************** PP BCCT 186 atvfGvatsLGlgvlqinaglself.giensltvqlliiavitavalisavsGldkGikvlSnlnvllavllllfvlivGptlfilnlfveslgdy 280 +t+fGv+tsLGlg +q+n+g+s++f +ie s+t q++ii+++ta+a++s+vsGl+ Gi++lS++ +++ ++++l+ +++ +t +iln++v+s+g y FUN_000521-T1 225 CTMFGVCTSLGLGCIQLNTGFSRVFeKIEFSKTNQIIIIWCVTACATASVVSGLKVGIRRLSEICFTIGMFIMLIGFFFKDTEHILNVYVQSIGYY 320 *************************779******************************************************************** PP BCCT 281 lqnlvelslrtdaleees.........ewlesWTiFywaWwiawapfvglFiAriSrGRtirefilgvllvptlvtllwftvfGgtalelelegeg 367 +qn+v+l ++tda+++ + +w+++WTiFyw+Wwiaw+pfvg+FiA+iS+GRti++fi g++ +p+l t+lwf +fG+++l++e+e e+ FUN_000521-T1 321 MQNIVQLGFHTDAFAQLGnapdgkqaqSWMNDWTIFYWGWWIAWSPFVGMFIAKISKGRTIKQFINGAMTAPILYTFLWFCIFGSAGLKMEREAEI 416 *************995445556666779************************************************************99997766 PP BCCT 368 elak..................a.aeaeveaalfalleql.plgtilsvlallliiiffvTsaDSatlvlamlsskgdeepsrllrvfWgvllgav 443 + ++ ++++++ f++++q+ lg +lsv+ l+ ii++fvTs+DS++lv++ ls++gd +p+ ++rvfW++++ga FUN_000521-T1 417 ANITcdsllggknskasmnglyRlSCRQTNEMWFDVMDQYgDLGVFLSVVSLIGIIFYFVTSSDSGSLVIDCLSANGDPDPPITQRVFWALTEGAC 512 444323333333333322222212334455555666666699****************************************************** PP BCCT 444 aavlllagg...lealqsasiiaalPfslilllmvvsllkalke 484 a+ ll+agg l+al+s+si+ ++P +++l +m+vsl++a+k FUN_000521-T1 513 ATSLLYAGGssgLKALRSMSIASGVPYAVLLSFMCVSLWRAVKM 556 *******88888****************************9986 PP >> PLAC8 PLAC8 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.1 2.4 1.5e+04 29 29 .. 51 51 .. 22 90 .. 0.53 2 ? 1.2 2.7 0.16 1e+03 8 94 .. 224 270 .. 197 315 .. 0.57 3 ? -2.3 0.0 1.9 1.2e+04 19 22 .. 399 402 .. 351 447 .. 0.58 4 ! 33.9 0.0 9.8e-12 6.3e-08 2 100 .. 569 691 .. 568 692 .. 0.71 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.4 PLAC8 29 n 29 FUN_000521-T1 51 D 51 2 PP == domain 2 score: 1.2 bits; conditional E-value: 0.16 PLAC8 8 cfsdlelclltlfcpcvlf....grnaerldkgntscllalvlvlllllllllglalilscllRsklRekygiegspceDclvhlcCecCa 94 c++ +++c +l + c+++ +r+ e ++ +t+ ++ +++v+ Ca FUN_000521-T1 224 CCTMFGVCT-SLGLGCIQLntgfSRVFEKIEFSKTNQIIIIWCVT-------------------------------------------ACA 270 444433333.33333333311114444444444333333222222...........................................111 PP == domain 3 score: -2.3 bits; conditional E-value: 1.9 PLAC8 19 lfcp 22 +fc FUN_000521-T1 399 WFCI 402 2222 PP == domain 4 score: 33.9 bits; conditional E-value: 9.8e-12 PLAC8 2 stglfdc.....fsdlelclltlfcpcvlfgrnaerldkgntscllalv.....lvllll...........lllllglalil.......scllRsk 69 stgl+d ++ +l+++++p++ +g++a ++ + +++++ ++l + + ++++ + ++ +R + FUN_000521-T1 569 STGLLDSlgsptLLNIRKVLVAVVAPWYPMGKAAYKIGGSKDRKWVYMLilaapFYL--WilllslepvvtG--ISYVGWTVlfgffanATAIRHT 660 677777656665557778999****************88866666555445545222..1334566666442..222333313344566889**** PP PLAC8 70 lRekygiegspceDclvhlcCecCalcQeer 100 +Reky+i g+++eD++++++ ++ a +Q+e FUN_000521-T1 661 IREKYNIYGNMVEDFFAVMITYPFAAIQMEH 691 *****************************86 PP >> DUF2721 Protein of unknown function (DUF2721) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.1 2.4 1.5e+04 97 116 .. 214 233 .. 211 235 .. 0.65 2 ? 9.1 0.9 0.00026 1.6 66 115 .. 258 303 .. 245 313 .. 0.79 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 2.4 DUF2721 97 laallFilslllllvslllf 116 ++ ++ ils+++ +++++++ FUN_000521-T1 214 IGDAIDILSVCCTMFGVCTS 233 55566677777777777766 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00026 DUF2721 66 aillgvlslllvvlvilllflsallsldlsllaallFilslllllvslll 115 +++++ ++ ++++++++ l ++++ l +++F ++++++l+++++ FUN_000521-T1 258 NQIIIIWCVTACATASVVSGL----KVGIRRLSEICFTIGMFIMLIGFFF 303 566666667777777777777....999******************9876 PP >> DUF7942 Family of unknown function (DUF7942) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.6 0.97 6.2e+03 22 41 .. 38 57 .. 32 89 .. 0.61 2 ? 11.1 1.2 6.3e-05 0.4 19 96 .. 588 661 .. 587 664 .. 0.63 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.97 DUF7942 22 allvwvlvdtllvdhedasf 41 a+++w++v + vd++ a FUN_000521-T1 38 AVAIWAFVIWCSVDSKRAET 57 45555555555544444444 PP == domain 2 score: 11.1 bits; conditional E-value: 6.3e-05 DUF7942 19 lvaallvwvlvdtll.vdhedasfagvwplllTaPtsllllll.lpgeeasgaaalsawlfvlavalgalvnAvllgala 96 lva+++ w + ++ + + +v++l+l+aP+ l +lll l+ + ++ ++ +v++g ++nA+++ FUN_000521-T1 588 LVAVVAPWYPMGKAAyKIGGSKDRKWVYMLILAAPFYLWILLLsLE-PV-----VTGISYVGWTVLFGFFANATAIRHTI 661 56666666655544424455566689***********665443232.22.....22333566678899999999997665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (780 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 986 (0.0385986); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.39u 0.41s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 7389.07 // Query: FUN_000522-T1 [L=420] Description: FUN_000522 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-35 122.8 1.9 5e-35 121.7 1.9 1.5 1 Alpha_kinase Alpha-kinase family ------ inclusion threshold ------ 0.57 11.4 4.3 0.81 10.9 0.2 2.8 3 DUF2462 Protein of unknown function (DUF2462) Domain annotation for each model (and alignments): >> Alpha_kinase Alpha-kinase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 121.7 1.9 4e-39 5e-35 1 185 [] 212 407 .. 212 407 .. 0.83 Alignments for each domain: == domain 1 score: 121.7 bits; conditional E-value: 4e-39 Alpha_kinase 1 aegamrkafkakvlkgeesgqkyVaKefkkeekkk.......elekykeevkvqalakelakeFn..aearllekkppkkieflpvlvleldeass 87 a+g++r+afka+ + sg ++V+K+++k + ++ ++++ + v++++la+++ + + e+++l ++++ +++ +v++ + s+ FUN_000522-T1 212 ASGGFREAFKATSDTPGFSGVTWVIKKYLKGTLEDiiktnqtVESHTRKAVQMHHLARNFTSQLKekVEKETLTEFGTS-FHYKKVFLG---KMSD 303 689********8778999**************99999976654444666667777777777777644445555555543.666666665...8889 PP Alpha_kinase 88 kkyylvEpflegefvKynsnsgfvededseleetmqAFsHftYersngqllvcDlqGvgnlLtDpaihtkdk......erfgetnlgeegiakFfe 177 +y+++E+f++g fvKy +n+g + +ed+ l +++q+F HftYe+s+g+l+v D+qG g L Dp i +++ rf +nl++ +i++Ff+ FUN_000522-T1 304 GDYVTIEEFIDGVFVKYINNNGDICTEDDVLCDKAQCFAHFTYEKSKGKLMVLDVQGAGLNLYDPEIASAELtdddgsLRFCNGNLADGAIKNFFA 399 99*******************************************************************444333456788*************** PP Alpha_kinase 178 thkcnkic 185 +h+cn +c FUN_000522-T1 400 KHNCNFYC 407 *******9 PP >> DUF2462 Protein of unknown function (DUF2462) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.1 0.091 1.2e+03 14 61 .. 37 85 .. 6 91 .. 0.70 2 ? -2.3 0.0 0.85 1.1e+04 30 53 .. 157 180 .. 140 184 .. 0.69 3 ? 10.9 0.2 6.3e-05 0.81 28 65 .. 251 288 .. 246 300 .. 0.84 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.091 DUF2462 14 akkakkkakn.pkkgarviaPKKaklvkqqklkkklsaglnkktEkela 61 ++++++k+++ + ga P + +++k ++ ++ ++Ek+l+ FUN_000522-T1 37 SAHVSGKQQKySRIGAQEYVPFEQDELSIHNIKDACQKHFQPQIEKDLV 85 4445555554255567777777777777888888899999999999886 PP == domain 2 score: -2.3 bits; conditional E-value: 0.85 DUF2462 30 viaPKKaklvkqqklkkklsagln 53 ++ PK ++v++ kl ++ ++ + FUN_000522-T1 157 KVYPKSLSVVEMLKLGNVIAKNTT 180 456888888888888777777666 PP == domain 3 score: 10.9 bits; conditional E-value: 6.3e-05 DUF2462 28 arviaPKKaklvkqqklkkklsaglnkktEkelasrAg 65 + ++ + k+v++++l ++++++l++k+Eke g FUN_000522-T1 251 NQTVESHTRKAVQMHHLARNFTSQLKEKVEKETLTEFG 288 6677788899*********************9876655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (420 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1448 (0.0566843); expected 510.9 (0.02) Passed bias filter: 898 (0.0351537); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 4039.09 // Query: FUN_000523-T1 [L=407] Description: FUN_000523 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-19 70.1 1.9 3.5e-19 69.8 1.2 1.4 2 rva_4 Integrase core domain 6.7e-06 26.7 0.1 2.8e-05 24.8 0.1 2.1 1 HTH_21 HTH-like domain ------ inclusion threshold ------ 0.11 13.0 0.1 5.9 7.4 0.0 2.7 3 ydhR Putative mono-oxygenase ydhR Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 1.3 1.1e+04 150 167 .. 48 65 .. 46 70 .. 0.82 2 ! 69.8 1.2 4.1e-23 3.5e-19 8 174 .. 143 321 .. 137 331 .. 0.82 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 1.3 rva_4 150 priqkeleefknawnnhk 167 + ++++l++f+ +n+ + FUN_000523-T1 48 RSLDRRLRHFEIYYNSNS 65 6788999***99999876 PP == domain 2 score: 69.8 bits; conditional E-value: 4.1e-23 rva_4 8 nslWhidgnmklirWr.....lvvhGaidgysrlivyleastnnrastvlkq.flkavkky.glPsrvrsdkggenvkval...lmnllrGle..r 91 n + +dg+ kl+ ++ l + G++d sr +++l++ n ++ + +l+ + + + + +r dkg+e ++a+ +++ +G + FUN_000523-T1 143 NWVHSLDGHDKLMGYQnstfpLAIYGCMDTASRKLLWLKVWVTNSDPQLIGRwYLEHLLQTkVISAIIRVDKGTETGTMATihsFLRRHHGDMdpH 238 666779999999876544444899****************9999888888652667665550566678*******877665111677777864337 PP rva_4 92 ssvitGrsvhnqrierlWrdvfkkvvsvfyslftaledseildidndihllalhivylpriqkeleefkna.wnnhklrteknk 174 ++v+ G s nq ier W+++++++ ++f++ + l d++ +++ ++++l l +v +p +qkel+ f+++ wn+h +r++k+ FUN_000523-T1 239 DTVVYGPSTSNQ-IERWWKELHERMEKYFKDQLSWLKDQGHYNPHRHTDRLLLAFVMVPLVQKELDVFRETvWNTHRIRAQKHT 321 899*****9998.*******************************************************9744*******99875 PP >> HTH_21 HTH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.1 3.3e-09 2.8e-05 8 51 .. 73 116 .. 68 123 .. 0.86 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.3e-09 HTH_21 8 elIkeifeesrgtYGyRritaeLrreggirvnrkrVaRLMrelg 51 ++++ + s + GyR +++ +r+e+g++v r++V+ M el+ FUN_000523-T1 73 QAVENELKGSGQLLGYRAMHKKIRQEYGLNVTRDKVYDVMYELD 116 5566666778899***************************9985 PP >> ydhR Putative mono-oxygenase ydhR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.5 1.3e+04 38 55 .. 9 26 .. 8 31 .. 0.74 2 ? 7.4 0.0 0.0007 5.9 60 89 .. 86 115 .. 80 118 .. 0.89 3 ? 2.4 0.0 0.024 2.1e+02 32 52 .. 177 197 .. 170 203 .. 0.83 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.5 ydhR 38 WteneetkeaGGiYlFed 55 W+++++ kea + Y+ ++ FUN_000523-T1 9 WVHDDKLKEAMSRYVQQS 26 888888888888887555 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0007 ydhR 60 eaYlemhtarlanfgieevrvkvFevnekl 89 Y +mh+++ ++ g++ r kv++v+ +l FUN_000523-T1 86 LGYRAMHKKIRQEYGLNVTRDKVYDVMYEL 115 5699**********************9876 PP == domain 3 score: 2.4 bits; conditional E-value: 0.024 ydhR 32 GliwKiWteneetkeaGGiYl 52 l K+W+ n++ + G +Yl FUN_000523-T1 177 LLWLKVWVTNSDPQLIGRWYL 197 3555***************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (407 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 954 (0.0373459); expected 510.9 (0.02) Passed bias filter: 802 (0.0313956); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.43s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3997.29 // Query: FUN_000524-T1 [L=391] Description: FUN_000524 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-10 42.0 0.0 2.6e-10 41.3 0.0 1.3 1 VWA von Willebrand factor type A domain ------ inclusion threshold ------ 0.013 16.4 0.6 0.03 15.2 0.6 1.6 1 TEX29 Testis-expressed sequence 29 protein Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.3 0.0 2.1e-14 2.6e-10 1 155 [. 182 352 .. 182 362 .. 0.86 Alignments for each domain: == domain 1 score: 41.3 bits; conditional E-value: 2.1e-14 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldi.........gpdstrvglvqyssevrtefslnd..ys.skeellsavkslkykgggttntgka 84 D++f++ + g +e+f k+ke +k l++++ + +++ + v ++++v+ + ++ ++ + ++l+++++sl+++g+ t + + FUN_000524-T1 182 DLCFIMNATGKKAQEDFAKIKECIKVLIRRIGVsstnyciisFKKGKAFQHVAFNKKVTYKNDEDRvvFQnDTNHLIRKLDSLNVSGNCTPALHDD 277 8999999*************************878888899978888888888888755444444322445779********************** PP VWA 85 lkyalenlfkssagaRegapkvvvlltdGksqd.g....dveeaarelksagvkvfavgvgnadeee.Lekiasepd 155 ++ale +fk+ a R +kv++llt + + + g ++ ar l + gvkv+ v++++ e Le+iase++ FUN_000524-T1 278 FEQALE-AFKHDAP-RNSSKKVLILLTNDSTGShGpqkgKLWHSARTLIDLGVKVVPVAIRDRPVVEdLENIASENR 352 ******.9999999.9************77766447778999******************87777777******997 PP >> TEX29 Testis-expressed sequence 29 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.6 2.4e-06 0.03 10 74 .. 162 226 .. 155 228 .. 0.91 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.4e-06 TEX29 10 DipLydiCdynvsrdrCkeLgcCfykgvCyekavpiYvqvfsaLivliagvlvitviyrviqesk 74 i L+ i + n r + keL+ Cf + +ka + ++ + vli + v y +i +k FUN_000524-T1 162 FIVLFAIHSVNKWRSKTKELDLCFIMNATGKKAQEDFAKIKECIKVLIRRIGVSSTNYCIISFKK 226 589**************************************************999999887665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (391 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1058 (0.0414171); expected 510.9 (0.02) Passed bias filter: 782 (0.0306126); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 3796.79 // Query: FUN_000525-T1 [L=127] Description: FUN_000525 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (127 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 638 (0.0249755); expected 510.9 (0.02) Passed bias filter: 512 (0.0200431); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1261.81 // Query: FUN_000526-T1 [L=501] Description: FUN_000526 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-08 34.8 13.1 1.7e-08 34.4 13.1 1.2 1 Ion_trans Ion transport protein ------ inclusion threshold ------ 3.6 8.3 9.5 0.11 13.2 1.5 2.5 3 DUF6704 Family of unknown function (DUF6704) Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.4 13.1 1.4e-12 1.7e-08 66 241 .. 3 202 .. 1 204 [. 0.71 Alignments for each domain: == domain 1 score: 34.4 bits; conditional E-value: 1.4e-12 Ion_trans 66 spwnilDfvvvlpslislil..........ses.......keslsllrvlrllrllrll.rlirrleglrtlvnslirslksllnlllllllvlfi 143 + wn+lDf+++++++++++l + ++ ++ ++ lr++ +l++ +++ t +li ++ +++ +++ +++ +++ FUN_000526-T1 3 DRWNVLDFIMLVIYVVTFMLrmitwgvsttA-TgnkalviA--GYFYGLNTMILTLRVFgHLMETSKTTGTTHIALISIIEDVAIIFFQFVVGVLA 95 89******************99998876551.144443321..33333333334444443455555555555569********************* PP Ion_trans 144 faiigvqlfggklkk......eekewenpdngrtnFdnfgnallwlfq...tlttegwgdilyatldek...gsaiaviyfvlfiilggvlllnll 227 f+++ ++ + ee+ ++ + +++ g + +w + + t g++++ + ++ ++ + ++a i++++fii + vll+n++ FUN_000526-T1 96 FSLAITKIYVA---QasfisrEERVARISEGINAECSISGASCWWEVMvhlVWTLLGITELDPFNTIGHessSDSLARILYGIFIIGALVLLVNMM 188 *****999922...2344555233444444555567776666666555476666667788877777777789999********************* PP Ion_trans 228 iaviidnfqelter 241 iav+++++++++++ FUN_000526-T1 189 IAVLSHTYERVQKN 202 *********99986 PP >> DUF6704 Family of unknown function (DUF6704) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.2 0.37 4.7e+03 23 62 .. 16 30 .. 4 44 .. 0.64 2 ? 13.2 1.5 8.3e-06 0.11 14 42 .. 81 109 .. 71 118 .. 0.88 3 ? -2.9 0.1 0.91 1.2e+04 19 33 .. 173 187 .. 162 192 .. 0.73 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.37 DUF6704 23 tvGtlafyldiaevvWasavlailGvvvGillkraGyGvs 62 vv +l+ +Gvs FUN_000526-T1 16 Y-------------------------VVTFMLRMITWGVS 30 3.........................45555565556655 PP == domain 2 score: 13.2 bits; conditional E-value: 8.3e-06 DUF6704 14 avsiilvaftvGtlafyldiaevvWasav 42 v+ii++ f+vG laf l i+++ a a FUN_000526-T1 81 DVAIIFFQFVVGVLAFSLAITKIYVAQAS 109 699********************999886 PP == domain 3 score: -2.9 bits; conditional E-value: 0.91 DUF6704 19 lvaftvGtlafyldi 33 f +G+l++ +++ FUN_000526-T1 173 YGIFIIGALVLLVNM 187 446889999887775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (501 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1191 (0.0466236); expected 510.9 (0.02) Passed bias filter: 708 (0.0277158); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4897.14 // Query: FUN_000528-T1 [L=107] Description: FUN_000528 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00018 22.4 2.7 0.00025 21.9 2.7 1.2 1 NPV_P10 Nucleopolyhedrovirus P10 protein 0.0022 17.4 3.2 0.0024 17.3 3.2 1.0 1 DNA_topoisoIV DNA gyrase/topoisomerase IV, subunit A 0.0034 18.3 9.3 0.0039 18.1 8.8 1.4 1 DUF16 Protein of unknown function DUF16 0.0044 17.0 6.5 0.0054 16.7 6.5 1.1 1 Flagellar_rod Paraflagellar rod protein 0.0084 16.7 10.6 0.0096 16.6 10.6 1.1 1 ApoLp-III Apolipophorin-III precursor (apoLp-III) ------ inclusion threshold ------ 0.014 16.1 0.8 0.014 16.1 0.8 1.7 2 V-SNARE_C Snare region anchored in the vesicle membran 0.021 15.4 1.0 0.026 15.2 1.0 1.1 1 CNOT11 CCR4-NOT transcription complex subunit 11 0.027 14.9 1.1 0.035 14.6 1.1 1.1 1 DUF4745 Domain of unknown function (DUF4745) 0.033 15.1 3.4 0.041 14.8 2.9 1.5 1 Goodbye fungal STAND N-terminal Goodbye domain 0.04 14.4 3.8 0.077 13.5 3.6 1.3 1 Laminin_II Laminin Domain II 0.044 14.2 1.2 0.053 13.9 1.2 1.2 1 DUF6270 Family of unknown function (DUF6270) 0.056 13.8 2.1 0.064 13.6 2.1 1.2 1 MCPsignal Methyl-accepting chemotaxis protein (MCP) si 0.073 13.5 7.2 0.083 13.3 6.5 1.6 1 betaPIX_CC betaPIX coiled coil 0.098 13.0 0.5 0.21 11.9 0.5 1.6 1 RFX5_N RFX5 N-terminal domain 0.13 12.8 3.7 0.16 12.6 3.7 1.1 1 DUF87 Helicase HerA, central domain 0.22 12.0 3.4 0.32 11.5 3.2 1.4 1 Phage_int_SAM_6 Phage integrase SAM-like domain 0.27 12.4 4.1 0.41 11.8 4.1 1.2 1 DUF2203 Uncharacterized conserved protein (DUF2203) 0.43 10.8 7.1 0.64 10.2 7.1 1.4 1 DUF1366 Protein of unknown function (DUF1366) 0.45 9.7 6.6 0.48 9.6 6.6 1.0 1 FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and cataly 0.63 10.4 7.9 0.81 10.1 7.9 1.0 1 Cauli_AT Aphid transmission protein 0.66 10.3 9.1 0.7 10.2 9.1 1.0 1 PCRF PCRF domain 0.71 9.0 1.9 0.85 8.7 1.9 1.1 1 Tweety Tweety 1.1 9.8 8.1 2 9.0 8.1 1.4 1 CREPT Cell-cycle alteration and expression-elevate 2 8.4 8.6 2.5 8.0 8.6 1.4 1 MG280 Uncharacterised protein MG280 2.3 8.0 4.1 2.7 7.8 4.1 1.1 1 DUF6720 Family of unknown function (DUF6720) 2.9 8.9 5.8 3.3 8.7 2.7 2.1 2 YtxH YtxH-like protein Domain annotation for each model (and alignments): >> NPV_P10 Nucleopolyhedrovirus P10 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 2.7 2.6e-07 0.00025 5 66 .. 34 96 .. 30 106 .. 0.89 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 2.6e-07 NPV_P10 5 iLlqIradikavddkVdalqqqv.ddleenlpdvtelnekLdaqsaqLaelqtkveeIqdiLn 66 iL q + +++v++ d lq+ v +++e+ ++v++ +e +++q+ +++e++ ++++I +iL FUN_000528-T1 34 ILYQTFESVEEVKESSDLLQEFVqEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILK 96 899999*****************4469999999*****************************8 PP >> DNA_topoisoIV DNA gyrase/topoisomerase IV, subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 3.2 2.4e-06 0.0024 289 355 .. 30 96 .. 4 105 .. 0.77 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.4e-06 DNA_topoisoIV 289 sisvnnlvlvdk.k..pkvlslkeilkeflehrlevlerrkeyelekleerleilegllkalnkidevie 355 + n++l++ + ++v++ +++l+ef++ ++e+++++ + ++e+ ee+ +++ + ++lnki ++++ FUN_000528-T1 30 EQ---NMILYQTfEsvEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILK 96 33...4455444434599**************************************88888888877754 PP >> DUF16 Protein of unknown function DUF16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 8.8 4e-06 0.0039 36 94 .. 39 97 .. 20 100 .. 0.84 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 4e-06 DUF16 36 LkkietkvdklgekidkleekvekqgeqikelkveqkaqgeelnkvdetleliletLqk 94 ++ +e+ ++ + ++ ++ekve+ ++++k++k++ + q+++++++++tl+ il++L++ FUN_000528-T1 39 FESVEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILKD 97 555555555666667778999***********************************986 PP >> Flagellar_rod Paraflagellar rod protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 6.5 5.5e-06 0.0054 90 164 .. 8 83 .. 2 91 .. 0.79 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 5.5e-06 Flagellar_rod 90 eaverEekRetdyeeFlkvaeqhkqk..LrktlenldkaldlarsleelVkegvkklkakqdklqqalnelllevrk 164 e++erE + +F+ + ++ +q L +t e ++++++ l+e+V+e v+++ ++ k++++++e+++++ + FUN_000528-T1 8 EQEERESLAS-SDHDFASIFSETEQNmiLYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIDE 83 2333333333.3446999987766653389****************************99************99865 PP >> ApoLp-III Apolipophorin-III precursor (apoLp-III) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 10.6 9.8e-06 0.0096 46 133 .. 12 96 .. 4 105 .. 0.82 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 9.8e-06 ApoLp-III 46 qeelkkasdeleealkelktk..ieetadklseenPevekkaqelqekvQssvqslvkesqklakkvkensqkaqeklqkaikqayddav 133 +e+l+ ++++++e+ ++ + +t+++++e v++ + lqe vQ++v+++ +e++k ++ +e+ +k+ e +++++ +++++ FUN_000528-T1 12 RESLASSDHDFASIFSETEQNmiLYQTFESVEE----VKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIDE-MNRTLNKILNILK 96 677888888999999999887446799999988....**********************************99975.7777777777655 PP >> V-SNARE_C Snare region anchored in the vesicle membrane C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 8.7 8.6e+03 3 14 .. 8 19 .. 6 22 .. 0.68 2 ? 16.1 0.8 1.5e-05 0.014 9 60 .. 44 96 .. 40 97 .. 0.88 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 8.7 V-SNARE_C 3 llresdrlknSh 14 ++ e+++l +S+ FUN_000528-T1 8 EQEERESLASSD 19 566777777776 PP == domain 2 score: 16.1 bits; conditional E-value: 1.5e-05 V-SNARE_C 9 rlknShrivdetisiGaail.edLhsQretLkrarsklhnvanrlgksnsiLr 60 +k+S+ ++ e+ + ++++ ++ ++Q+et++ ++k+ + + +l k+ iL+ FUN_000528-T1 44 EVKESSDLLQEFVQEKVETItQEVKKQKETFEEQNRKIDEMNRTLNKILNILK 96 688999999999998888653789***************************97 PP >> CNOT11 CCR4-NOT transcription complex subunit 11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 1.0 2.6e-05 0.026 19 80 .. 20 82 .. 10 101 .. 0.83 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.6e-05 CNOT11 19 seakeyldvlvslevtlnslevvnrllkssklpkefvhkyisnciksceeik.dkesqerlvr 80 ++++++++ ++ + +++e v+++ +ss+l +efv++ +++ + ++++k e q+r++ FUN_000528-T1 20 HDFASIFSETEQNMILYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQKeTFEEQNRKID 82 5678889999999999**********************************9955677888875 PP >> DUF4745 Domain of unknown function (DUF4745) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 1.1 3.5e-05 0.035 41 112 .. 20 91 .. 14 99 .. 0.86 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.5e-05 DUF4745 41 dslaallrnsipsklamqlktvwedlvrAstvatstiKseilslLqefstmaassvdqesfslldiqrire.i 112 + +a+++ ++ ++ + +q ++ e++ + s + ++ ++ + qe + + ++ +q+ +++r+ + i FUN_000528-T1 20 HDFASIFSETEQNMILYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNR-KIDEMNRTLNkI 91 789************************************************999999998.555666654433 PP >> Goodbye fungal STAND N-terminal Goodbye domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 2.9 4.2e-05 0.041 20 64 .. 53 97 .. 36 104 .. 0.86 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 4.2e-05 Goodbye 20 elkelksvedllkqieaekdkfeefrekkeklkealkkilkpiel 64 + +++ve + ++++++k+ fee+++k ++++++l+kil++++ FUN_000528-T1 53 QEFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILKD 97 4456789*********************************99876 PP >> Laminin_II Laminin Domain II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 3.6 7.8e-05 0.077 14 56 .. 54 97 .. 41 103 .. 0.58 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 7.8e-05 Laminin_II 14 e.vleqlaplsqnlentkeklseinrsveetnekvkdankalrd 56 e v+e+++ + q++++ ke +e nr+++e+n +++ ++l+d FUN_000528-T1 54 EfVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILKD 97 32666666666666666666666666666666666665555544 PP >> DUF6270 Family of unknown function (DUF6270) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 1.2 5.4e-05 0.053 117 194 .. 25 99 .. 3 106 .. 0.74 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 5.4e-05 DUF6270 117 iefgsdehfalwkealdrlaellkeaglrakvvllkvpwaeelddggkeeetpksfgeeakeaNellaryydaleeal 194 i ++++ + l+ + ++ + e ++ +l +++v kv ++ +++ +et+++++ +++e+N+ l++++++l++++ FUN_000528-T1 25 IFSETEQNMILY-QTFESVEEVKESSDLLQEFVQEKVETITQEVKKQ--KETFEEQNRKIDEMNRTLNKILNILKDKG 99 444444444444.4567777777788899999999999997777766..89999999*****************9988 PP >> MCPsignal Methyl-accepting chemotaxis protein (MCP) signalling domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 2.1 6.5e-05 0.064 116 169 .. 38 92 .. 6 95 .. 0.81 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 6.5e-05 MCPsignal 116 veegselveetgealkeiv.eavaevadlvqeiaaaseeqsagieevnqaveevd 169 + e++e+v+e+ + l+e v e+v+ ++++v+ + + eeq + i+e+n++++++ FUN_000528-T1 38 TFESVEEVKESSDLLQEFVqEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKIL 92 4567888999999999977368999***********************9999875 PP >> betaPIX_CC betaPIX coiled coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 6.5 8.4e-05 0.083 37 83 .. 56 102 .. 23 104 .. 0.86 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 8.4e-05 betaPIX_CC 37 lkdevqelkqdnkklkkalEeEqkaRkdLEklvrkllksinddasde 83 ++++v+ + q+ kk k+++Ee + ++++ ++k+l+ ++d++ ++ FUN_000528-T1 56 VQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILKDKGAEQ 102 6899************************************9998765 PP >> RFX5_N RFX5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.5 0.00022 0.21 14 28 .. 55 69 .. 45 75 .. 0.89 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00022 RFX5_N 14 avqskvegiLqevek 28 vq+kve+i qev+k FUN_000528-T1 55 FVQEKVETITQEVKK 69 59***********99 PP >> DUF87 Helicase HerA, central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 3.7 0.00016 0.16 95 176 .. 20 98 .. 13 106 .. 0.69 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00016 DUF87 95 eeladlleekneeaaevqreileealeelkk....eekeklsidelieklleelkeekeelnkakedairavldklerllrsggli 176 +++a+++ e ++q il++++e++++ + ++e +e++ +e+k +++e+ +++++ i +++++l+++l+ +++ FUN_000528-T1 20 HDFASIFSE------TEQNMILYQTFESVEEvkesSDLLQEFVQEKVETITQEVK-KQKETFEEQNRKIDEMNRTLNKILNILKDK 98 566666666......7899999999999986654444444445555666666666.666888888888888888888888877766 PP >> Phage_int_SAM_6 Phage integrase SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 3.2 0.00033 0.32 14 59 .. 52 97 .. 40 101 .. 0.91 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00033 Phage_int_SAM_6 14 lerfvkskltsLsnkevkdkkklakviqelkkgvksieelkkivke 59 l+ fv++k+ +++++ k+k+++++ + ++ + ++++++ +i+k+ FUN_000528-T1 52 LQEFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILKD 97 899***********9999**********************999996 PP >> DUF2203 Uncharacterized conserved protein (DUF2203) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 4.1 0.00042 0.41 2 76 .. 25 101 .. 24 104 .. 0.85 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00042 DUF2203 2 lFtleeAnalLpllreileeiralkaeleelee.eleeakaeaekkeg.aaeleaelkeleaeleelleeleelGve 76 +F+ e n +L + e +ee+++ + l+e + ++e++++e++k+++ ++e++++++e++ l+++l+ l++ G+e FUN_000528-T1 25 IFSETEQNMILYQTFESVEEVKESSDLLQEFVQeKVETITQEVKKQKEtFEEQNRKIDEMNRTLNKILNILKDKGAE 101 6888899999999999999999999999997653778888887777667999999*****************99986 PP >> DUF1366 Protein of unknown function (DUF1366) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 7.1 0.00065 0.64 65 113 .. 54 102 .. 25 105 .. 0.88 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00065 DUF1366 65 rAenEkFneldeliekakasiektEemlkaatetLneiidklkeeealt 113 +Ek + +++ ++k k++ e +++++ +++ tLn+i++ lk++ a++ FUN_000528-T1 54 EFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNILKDKGAEQ 102 5568***********************************9999887765 PP >> FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalytic domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 6.6 0.00049 0.48 38 103 .. 28 93 .. 6 105 .. 0.78 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00049 FUT8_N_cat 38 eeesskrleevlekleelkkqneelkellekrleeseeekkkaeeklksleeklekakekleeakk 103 e e+ l ++ e++ee+k+ ++ l+e++++++e+ ++e kk++e+ ++++ k+++ +++l+++ + FUN_000528-T1 28 ETEQNMILYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILN 93 35566778999************************9999999999999999999998877655544 PP >> Cauli_AT Aphid transmission protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 7.9 0.00082 0.81 72 160 .. 9 97 .. 7 99 .. 0.72 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00082 Cauli_AT 72 kDesealsksksPfgsvfkklk..kifkeggedkekktklletLkea.qnrikkleeetkklaekivtekllkeevkdlderlkeirdslka 160 ++e e+l+ s f+s+f++++ i+ ++ e+ e+ + + L+e q++++ + +e+kk +e + + ++ +++++l++i + lk+ FUN_000528-T1 9 QEERESLASSDHDFASIFSETEqnMILYQTFESVEEVKESSDLLQEFvQEKVETITQEVKKQKETFE---EQNRKIDEMNRTLNKILNILKD 97 6778999999999999998765115788999999999999999999625577777777777776644...4455666677777777666664 PP >> PCRF PCRF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 9.1 0.00071 0.7 6 92 .. 4 93 .. 1 104 [. 0.83 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00071 PCRF 6 eeleeklsdpevisdqkkaqklskelseleevvekleelkkaledleeakellkeedeelaelaeee...leelekkleeleeelkllLl 92 ++++e+ ++++++s+ ++++++ +e ++ +++++e++++++e+ + ++e+++e+ e ++++++++ +ee ++k++e+++ l+++L FUN_000528-T1 4 SDVQEQEERESLASSDHDFASIFSETEQNMILYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQketFEEQNRKIDEMNRTLNKILN 93 678999999999999**************************************9777777776655323488888899999998888886 PP >> Tweety Tweety # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 1.9 0.00087 0.85 104 168 .. 30 94 .. 24 104 .. 0.80 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00087 Tweety 104 etndGvlqltyslrnanhtlsgikklvsetkesleeklkeeLtkleeilakrtdylqavrklqra 168 e n ++q ++s++++ + +++ v+e++e++++++k++ ++ ee+ k ++ ++++k+ + FUN_000528-T1 30 EQNMILYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIDEMNRTLNKILNI 94 55556789999999999999999999999999999999999999999988888888888776544 PP >> CREPT Cell-cycle alteration and expression-elevated protein in tumour # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 8.1 0.002 2 69 125 .. 40 97 .. 3 101 .. 0.69 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.002 CREPT 69 aeledRkkvekmLedflalqkellakaeerlee.ykeklekvkqvrkelkshlesLPd 125 + +e+ k+ + +L++f++++ e+++++ ++++e + e+ +k+++++++l+++l+ L d FUN_000528-T1 40 ESVEEVKESSDLLQEFVQEKVETITQEVKKQKEtFEEQNRKIDEMNRTLNKILNILKD 97 46788899999*********999998877766637889999*********99988765 PP >> MG280 Uncharacterised protein MG280 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 8.6 0.0026 2.5 67 106 .. 52 94 .. 6 105 .. 0.73 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0026 MG280 67 adqfskesiqklleevkke...lekskkkleeyekklekqknl 106 ++f +e++++ +evkk+ +e+ ++k++e+++ l+k n+ FUN_000528-T1 52 LQEFVQEKVETITQEVKKQketFEEQNRKIDEMNRTLNKILNI 94 3567777777777777664333899999999999999998773 PP >> DUF6720 Family of unknown function (DUF6720) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 4.1 0.0028 2.7 45 105 .. 33 94 .. 19 96 .. 0.85 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0028 DUF6720 45 vflldekkekdekkieedeseeldkekeeelelknkkrrkvirkikkkv.kikrafddflfl 105 + l+++++ +e k + d +e+ +ek e+++ + kk++++++++++k+ ++r+++ l + FUN_000528-T1 33 MILYQTFESVEEVKESSDLLQEFVQEKVETITQEVKKQKETFEEQNRKIdEMNRTLNKILNI 94 56899*********999999*************99******998888662578888777765 PP >> YtxH YtxH-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 2.7 0.0034 3.3 33 68 .. 41 76 .. 35 79 .. 0.78 2 ? 3.9 0.7 0.11 1e+02 22 54 .. 69 101 .. 68 105 .. 0.68 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0034 YtxH 33 kaedlkdkleelleea.kekaedlkekvkekadelke 68 ++e++k++ +ll+e+ +ek+e+++++vk++ + e FUN_000528-T1 41 SVEEVKESS-DLLQEFvQEKVETITQEVKKQKETFEE 76 566776666.6666667*************9998776 PP == domain 2 score: 3.9 bits; conditional E-value: 0.11 YtxH 22 sGketRkklkkkaedlkdkleelleeakekaed 54 + ket ++ ++k++++ l++ l+ +k+k+++ FUN_000528-T1 69 KQKETFEEQNRKIDEMNRTLNKILNILKDKGAE 101 568888888888888888887776666666554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4333 (0.169622); expected 510.9 (0.02) Passed bias filter: 1267 (0.0495987); expected 510.9 (0.02) Passed Vit filter: 163 (0.0063809); expected 25.5 (0.001) Passed Fwd filter: 26 (0.00101781); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 26 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 1071.07 // Query: FUN_000529-T1 [L=508] Description: FUN_000529 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-195 650.2 0.1 1.9e-195 649.9 0.1 1.1 1 Catalase Catalase 6.2e-21 74.8 0.1 3.4e-20 72.5 0.0 2.1 2 Catalase-rel Catalase-related immune-responsive ------ inclusion threshold ------ 0.22 12.6 0.0 0.72 10.9 0.0 1.8 2 DUF8148 Domain of unknown function (DUF8148) N-terminal Domain annotation for each model (and alignments): >> Catalase Catalase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 649.9 0.1 2.2e-199 1.9e-195 1 382 [. 25 406 .. 25 407 .. 0.99 Alignments for each domain: == domain 1 score: 649.9 bits; conditional E-value: 2.2e-199 Catalase 1 ttseGapvadnqnsltagerGplllqdvhlieklahfdreripeRvvhAkGagahgefevtediskltkakllsevgkktpvfvRfStvagekgsa 96 tt G+pv+++++++t+g+rGp+llqdv+++++++hfdreripeRvvhAkG ga+g+f+vt+d++k++kak+++++gk+tp++vRfStv+ge+gsa FUN_000529-T1 25 TTGYGVPVDTKTSTMTVGPRGPILLQDVQFLDEMSHFDRERIPERVVHAKGGGAFGYFQVTHDVTKYCKAKIFDRIGKRTPCVVRFSTVGGESGSA 120 6788******************************************************************************************** PP Catalase 97 dtaRdvrGfavkfyTeeGnwDlvgnntpvFfirDaikFpdlihaqkrepktnlkdaaafwdflslnpeslhqvtilfsdrgipksyrhmngfgvht 192 dtaRd+rGfa+kfyTeeGnwDlvgnntp+FfirD+i Fp++ih+qkr+p t+lkd+++fwdf++l+pe++hqv++lfsdrgip++y+hmng+g+ht FUN_000529-T1 121 DTARDPRGFAMKFYTEEGNWDLVGNNTPIFFIRDPILFPSFIHTQKRNPVTHLKDPDMFWDFITLRPETTHQVCFLFSDRGIPDGYQHMNGYGSHT 216 ************************************************************************************************ PP Catalase 193 fklvnaegeavyvkfhfktkqgvknltaeeaeklagkdpdyatrdLyeaiekgeypewelyvqvmteeeaeklkfnifDlTkvwpekevplrevGk 288 fklvn++geavy+kfh+kt+qgvk + +++ae+lag+dpdy++r Ly+ai++ge p+w++y+qvmt eeae++k+n+fDlTk+wp++e+pl++vGk FUN_000529-T1 217 FKLVNDKGEAVYCKFHVKTDQGVKCVATDKAEQLAGSDPDYNNRMLYNAIANGEPPSWTMYIQVMTFEEAENFKWNPFDLTKIWPHSEYPLIPVGK 312 ************************************************************************************************ PP Catalase 289 lvLnrnpenyFaevEqvafspsnlvpGiefseDklLqgRlfsYaDtqryRlgvnyeqlpvNrp.kvkvanyqrdGamrveankgkepnYepnsle 382 +vLnrnp+nyFae+Eq af+p+++vpGie+s+Dk+LqgRlfsY+Dt+++Rlg+ny qlpvN+p k++v+nyqrdG +++++++g+ pnY+pns++ FUN_000529-T1 313 MVLNRNPKNYFAEIEQSAFNPASMVPGIEPSPDKMLQGRLFSYHDTHLHRLGANYLQLPVNCPfKTRVTNYQRDGPQTFDNQEGA-PNYYPNSFS 406 ***************************************************************999999*********9666655.******986 PP >> Catalase-rel Catalase-related immune-responsive # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.24 2e+03 31 47 .. 55 71 .. 53 73 .. 0.87 2 ! 72.5 0.0 4e-24 3.4e-20 3 65 .] 432 493 .. 429 493 .. 0.95 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.24 Catalase-rel 31 afelskvkdeeiqerml 47 +e+s+ ++e i er++ FUN_000529-T1 55 LDEMSHFDRERIPERVV 71 579***********998 PP == domain 2 score: 72.5 bits; conditional E-value: 4e-24 Catalase-rel 3 sfedhfsQagllyr.slseeererlvkniafelskvkdeeiqermlehlakvDpdlgqrVaeal 65 + ed+fsQ + +++ +lse er rlv+nia++l+++k e+i++r++ ++++v+p++g+r++++l FUN_000529-T1 432 D-EDNFSQVTSFWNkVLSEGERTRLVNNIAGHLKDAK-EFIRKRAIRNFSQVSPEFGRRLTDKL 493 4.7*********************************9.*********************99876 PP >> DUF8148 Domain of unknown function (DUF8148) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 8.4e-05 0.72 38 62 .. 235 259 .. 206 276 .. 0.76 2 ? -2.7 0.0 1.5 1.3e+04 18 28 .. 452 462 .. 449 486 .. 0.58 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 8.4e-05 DUF8148 38 vsvvlkGvsadalerlDGsDsdyqf 62 + + +k v +d++e+l GsD+dy FUN_000529-T1 235 TDQGVKCVATDKAEQLAGSDPDYNN 259 45789******************74 PP == domain 2 score: -2.7 bits; conditional E-value: 1.5 DUF8148 18 rvrllkfiaek 28 r+rl++ ia + FUN_000529-T1 452 RTRLVNNIAGH 462 55555555544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (508 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 601 (0.0235271); expected 510.9 (0.02) Passed bias filter: 571 (0.0223527); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 5002.82 // Query: FUN_000530-T1 [L=114] Description: FUN_000530 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0082 16.7 0.1 0.012 16.2 0.1 1.1 1 DUF1151 Protein of unknown function (DUF1151) ------ inclusion threshold ------ 0.078 13.5 0.1 0.11 13.0 0.1 1.2 1 UspB Universal stress protein B (UspB) Domain annotation for each model (and alignments): >> DUF1151 Protein of unknown function (DUF1151) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.1 9.2e-07 0.012 13 48 .. 48 83 .. 45 88 .. 0.93 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 9.2e-07 DUF1151 13 vleskshqeLHrELllnhkrklvleqKsELqrvlek 48 v+ s++h e+H+ +++ +k+k v +++ EL rv e+ FUN_000530-T1 48 VKVSAEHFEIHKSIIFVAKCKKVRQERHELPRVCER 83 67899****************************996 PP >> UspB Universal stress protein B (UspB) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 8.4e-06 0.11 39 88 .. 24 72 .. 12 84 .. 0.85 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 8.4e-06 UspB 39 llyqqvdGrgfftthgqvskqvrlvryiksqeyldhhdpevilkcervrk 88 +l+q+++ f ++ + q l+ + ++++ h ++ kc++vr+ FUN_000530-T1 24 VLFQNIENGFHFIDRNAFISQY-LFVKVSAEHFEIHKSIIFVAKCKKVRQ 72 6899999888888888888886.66669999******************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (114 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 571 (0.0223527); expected 510.9 (0.02) Passed bias filter: 418 (0.0163633); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.33s 00:00:00.60 Elapsed: 00:00:00.38 # Mc/sec: 1192.79 // Query: FUN_000531-T1 [L=376] Description: FUN_000531 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-36 126.2 9.9 3.1e-36 125.7 9.9 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.0091 15.8 0.5 0.0091 15.8 0.5 2.4 3 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw ------ inclusion threshold ------ 0.056 14.1 0.5 0.056 14.1 0.5 2.4 2 DUF4293 Domain of unknown function (DUF4293) 0.81 10.1 6.5 0.48 10.9 1.3 2.6 2 DUF7027 Domain of unknown function (DUF7027) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 125.7 9.9 4.8e-40 3.1e-36 1 260 [] 37 289 .. 37 289 .. 0.93 Alignments for each domain: == domain 1 score: 125.7 bits; conditional E-value: 4.8e-40 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN++ +lv++++ + +++++ +++n a+aD+ ++l+ p+a+ +l +++ + + C+ +++ + +++si++lt +s+ Y + + +++++ FUN_000531-T1 37 GNVMTLLVLFQHEHRKKAMTPYMVNIALADIFIILFGYPVAMRANL--RGKILESSHCNWGGFVNGAVGISSIFTLTEMSFVSYHGLRQV-NRSSR 129 8*****************************************9999..899999********************************9885.55578 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..x RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks..k 190 ++ ++++ ++v+W++++l++lpp+l g++++ + ++ +C +d++ +s +++ y+lll+++gf+ pl+ ++vcy++i++ ++++ + FUN_000531-T1 130 LSPFQVVCSVAVAWLYGVLCMLPPFL--GWNRFVVSASRISCCPDWSG-KSISDAAYNLLLVFFGFVAPLTAMTVCYYKIYSLVHHAVVPGNLpqI 222 ************************99..78899888**********98.667**********************************9998876223 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 191 kkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + +++++e k++k++++ v++f+l w+Py +++l +++ +++ lv++ +i +lla ++ ++ PiiY FUN_000531-T1 223 QLRRRQSELKVAKVTAMNVIAFLLSWAPYCCVSLAAVF---TKQFVLVDWEAEIPELLAKASVIYGPIIY 289 444455566*****************************...***************************** PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.5 1.4e-06 0.0091 3 50 .. 27 74 .. 25 96 .. 0.86 2 ? -3.7 0.2 1.2 7.8e+03 127 148 .. 185 206 .. 178 215 .. 0.54 3 ? 2.7 0.1 0.014 87 240 318 .. 232 306 .. 219 307 .. 0.78 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.4e-06 7TM_GPCR_Srw 3 efilsivgviinifHliiLtrksmrtssinilmiGIaicDiltmllti 50 f++ vg++ n++ l++L++ + r+ ++ m+ Ia++Di+ +l+ FUN_000531-T1 27 MFFILTVGFLGNVMTLLVLFQHEHRKKAMTPYMVNIALADIFIILFGY 74 68999*************************************998755 PP == domain 2 score: -3.7 bits; conditional E-value: 1.2 7TM_GPCR_Srw 127 iilivlllsllisilkyfryei 148 ++l+ + + ++++++++ y+i FUN_000531-T1 185 LLLVFFGFVAPLTAMTVCYYKI 206 4444555555555554444444 PP == domain 3 score: 2.7 bits; conditional E-value: 0.014 7TM_GPCR_Srw 240 kttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifsllltinsisHflicllmSsqYRktvkklfgc 318 k k + i f+++ +p+ ++ +++++ ++ +++ + i +ll + i +i+ +m s+ + t +++ c FUN_000531-T1 232 KVAKVTAMNVIAFLLSWAPYCCVSLAAVFTKQ----FVLVDWEAEIPELLAKASVIYGPIIYSTMHSRFQATLFRILHC 306 44555566678899999999999999877666....34666667788999999999999*********99999999887 PP >> DUF4293 Domain of unknown function (DUF4293) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.5 8.8e-06 0.056 48 127 .. 17 97 .. 3 112 .. 0.80 2 ? -0.1 0.5 0.2 1.3e+03 60 78 .. 187 205 .. 139 267 .. 0.64 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 8.8e-06 DUF4293 48 ggvstetstiallilll..laallalvtIflyknRklQirlcllnlllllgllvllvllilseqkelseesfaeesikigll 127 ++++ ++ +++++il++ l +++l+ +f+++ Rk+ ++ ++n+ l ++++l+ + + + ++l + ++++++++g + FUN_000531-T1 17 KASYYAYGVVMFFILTVgfLGNVMTLLVLFQHEHRKKAMTPYMVNIALADIFIILFGY-PVAMRANLRGKILESSHCNWGGF 97 45566788888888886336789***********************************.77777777777777788887755 PP == domain 2 score: -0.1 bits; conditional E-value: 0.2 DUF4293 60 lillllaallalvtIflyk 78 l+++ ++a l+ +t+ yk FUN_000531-T1 187 LVFFGFVAPLTAMTVCYYK 205 4444455555555555554 PP >> DUF7027 Domain of unknown function (DUF7027) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 1.3 7.5e-05 0.48 34 92 .. 20 78 .. 7 84 .. 0.82 2 ? 0.9 0.3 0.096 6.1e+02 8 55 .. 104 150 .. 101 151 .. 0.70 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 7.5e-05 DUF7027 34 ddaswfeivlilvslivaitsalLiiGiikekekllyPtLvarvilvifvqvfgvsiiv 92 + a+ +++++il++ +++ ++ lL++ + +++k + P +v ++ if+ +fg ++ FUN_000531-T1 20 YYAYGVVMFFILTVGFLGNVMTLLVLFQHEHRKKAMTPYMVNIALADIFIILFGYPVAM 78 345556778888889999999********************************987665 PP == domain 2 score: 0.9 bits; conditional E-value: 0.096 DUF7027 8 sveivvsvlvllvsiiyialsnekekddaswfeivlilvslivaitsa 55 +++i+ + + +vs +++ + n+++ ++ ++++++v+ ++++ ++ FUN_000531-T1 104 ISSIFTLTEMSFVSYHGLRQVNRSSR-LSPFQVVCSVAVAWLYGVLCM 150 56666777778888888887777553.345567899999999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (376 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 801 (0.0313564); expected 510.9 (0.02) Passed bias filter: 415 (0.0162458); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3710.36 // Query: FUN_000532-T1 [L=635] Description: FUN_000532 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (635 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 737 (0.028851); expected 510.9 (0.02) Passed bias filter: 405 (0.0158544); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.36u 0.40s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 6036.83 // Query: FUN_000533-T1 [L=3338] Description: FUN_000533 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-40 137.8 29.2 3.3e-21 76.5 5.5 3.5 2 Lectin_C Lectin C-type domain 1.1e-32 113.8 3.8 2.2e-16 60.8 0.2 5.0 4 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 4.5e-22 79.4 0.1 1.5e-21 77.8 0.1 2.0 1 PLAT PLAT/LH2 domain 2.1e-16 60.4 9.2 6.5e-16 58.9 9.2 1.9 1 WSC WSC domain 2.7e-15 56.9 0.8 3.5e-07 30.6 0.0 3.0 2 PA14 PA14 domain 1.4e-07 32.2 15.2 1.3e-05 25.9 1.1 3.9 3 GLEYA GLEYA domain 5.8e-06 27.3 8.7 2e-05 25.6 8.7 2.0 1 ShK ShK domain-like 6.5e-06 26.8 6.8 1.9e-05 25.3 6.8 1.9 1 EGF EGF-like domain 0.0079 16.0 0.2 1.4 8.7 0.1 2.5 2 Chordopox_A33R Chordopoxvirus A33R protein ------ inclusion threshold ------ 0.015 15.4 0.1 0.28 11.3 0.0 2.4 2 Pentaxin Pentaxin family 0.067 12.6 0.0 0.12 11.9 0.0 1.3 1 PAD Protein-arginine deiminase (PAD) 0.26 11.9 3.3 1.4 9.5 0.5 2.9 3 CHU_C CHU_C Type IX secretion signal domain Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.8 7.0 1.1e-23 2.4e-20 2 107 .] 1727 1829 .. 1726 1829 .. 0.97 2 ! 76.5 5.5 1.6e-24 3.3e-21 2 107 .] 1856 1956 .. 1855 1956 .. 0.98 Alignments for each domain: == domain 1 score: 73.8 bits; conditional E-value: 1.1e-23 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllkksnkkfWigltdeksegtwkwedgskvnteeytnw...epnnngenedCvelekssgkw 92 +k+w++a+++C++ gg+L+s++++ e++fl+++ +n + W+g++d+ ++gtw+w+d+s +tnw +n+ng+ dCv+l+++ gkw FUN_000533-T1 1727 RKTWDNAHSTCKNLGGELFSVTNAYEQRFLENF---TNIESWLGYRDKSRDGTWSWSDSSLSV---FTNWdssTKNDNGKGRDCVVLNAEEGKW 1814 79*******************************...69*************************...999999999******************* PP Lectin_C 93 ndesCnsknpfvCek 107 +d +C++ + ++C+k FUN_000533-T1 1815 KDAPCKETKEYLCKK 1829 *************96 PP == domain 2 score: 76.5 bits; conditional E-value: 1.6e-24 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllkksnkkfWigltdeksegtwkwedgskvnteeytnw.epnnngenedCvelekssgkwnd 94 kk we+a C e+++L+si s e+ ++s++ s+++fWig++d ++eg+w w+d + + ytnw ++++n++ +C+ + +++g+w+d FUN_000533-T1 1856 KKAWEHALVSCMDEKASLASILSDDEQTMISQVY--SKSNFWIGYNDIDNEGDWVWTDRATSS---YTNWdDKSPNNGGVSCAIV-TTNGRWHD 1943 799******************************7..***************************...*****99************.******** PP Lectin_C 95 esCnsknpfvCek 107 e+C+s++ f+C+k FUN_000533-T1 1944 EPCQSQYGFICKK 1956 ***********96 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.1 0.0 1.5e-10 3.2e-07 11 145 .. 2057 2196 .. 2048 2201 .. 0.70 2 ! 14.8 0.0 1.5e-05 0.033 44 150 .. 2301 2419 .. 2257 2420 .. 0.73 3 ? 3.7 0.1 0.04 86 38 106 .. 2487 2562 .. 2475 2603 .. 0.60 4 ! 60.8 0.2 1.1e-19 2.2e-16 4 150 .. 2822 2969 .. 2818 2970 .. 0.86 Alignments for each domain: == domain 1 score: 31.1 bits; conditional E-value: 1.5e-10 Laminin_G_3 11 daslttsafTvsaWvkpds..apqs.sralvsessgggyelgl.dsdgqlrftvnggngaeeavtsgasvpagqWtHvavtyd.ggtlrlYvnG 99 d +l ++f++++ ++ d+ ++++ +r+++ +ssg+++ + + g+l+ v++++ ++++ + ++ ++qW+ +++t+ ++l lYvnG FUN_000533-T1 2057 DPDLCIKGFSFALQLNFDDdaLSYTdKRLIL-DSSGDSRGVAVfIKHGSLYYKVTTST---KEWQLSTELVTNQWQDIVMTWKkEEGLMLYVNG 2146 5666667777777777777443333144444.67777888887346679999999887...5566677999************4466******* PP Laminin_G_3 100 eevgsstltga..ltkatggplyiGrdngg..dspfdGlidevriynraL 145 + ++s + + l +++++ l+iGr++g+ +++ +i + ++r L FUN_000533-T1 2147 AFRDSLKEGREtsLVPNKQARLTIGRKSGNppFKYTRMYISSLFAFTRFL 2196 *****8765554566689999******98534555555555555555555 PP == domain 2 score: 14.8 bits; conditional E-value: 1.5e-05 Laminin_G_3 44 g......gyelgldsdgqlrftvnggngaee.avtsgasvpagqWtHvavtyd.ggtlrlYvnGeevgsstltgaltk...atggplyiGrdn. 125 g g++ +l + ++l+f+v+ ++ + + ++t s+ + +W+ v+ ++ +++l lY + + +g ++++ ++++ +g +++Gr+n FUN_000533-T1 2301 GhvkgtrGLSAYLLN-NNLYFSVAMSTDEDTlTWTVRTSIFTVRWQRVVLSWSlSDGLWLYTDSQFRGWTKTPKSVPRdvmEESGEFIVGRKNv 2393 235554455555544.5777777777643335888999***************999************998888844435689**********7 PP Laminin_G_3 126 .ggdspfdGlidevriynraLsaeei 150 ++ sp +i ++++ r L +++ FUN_000533-T1 2394 gSDVSPAEFSIGSLAVFPRFLEKKDV 2419 54599***************999887 PP == domain 3 score: 3.7 bits; conditional E-value: 0.04 Laminin_G_3 38 vsessgggyelgldsdgqlrftvnggngaee..avtsgasvpa.gqWtHvavtyd.....ggtlrlYvnGeevgsst 106 v + +g+y+++++++++ ++++++++ +++ ++ s +++ +qW+ +a+ + + + Y G+++gs + FUN_000533-T1 2487 V-APETGNYTFYMSGSQSGELWMSSTERQQNltKLVSMDQPTGhNQWNKYAGQSSrsvnlEAGKYYYTIGVQKGSES 2562 4.3456899999988887777777776444444444444444459**999998884333223356666666666654 PP == domain 4 score: 60.8 bits; conditional E-value: 1.1e-19 Laminin_G_3 4 ddyvtlpd.aslt.tsafTvsaWvkpdsapqssralvsessgg.gyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtydggt.. 92 d+ v++p+ ++ +++T+ a ++p+ +++ ++l ++g g++l+ ++++l++++ ng + +++ ++++ W++v +tyd++t FUN_000533-T1 2822 DSFVEIPNdGKMDtKNSMTILANIYPTGSGG--PILN-YKTDGwGVHLWQFESTELFVRFVHRNGVFHKPIASRVLQLNDWNQVGATYDNNTgv 2912 678999998777669***************9..5555.233445777777999999999988888788888999999************65556 PP Laminin_G_3 93 lrlYvnGeevgsstltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeei 150 ++l nG++v+s+++ g+++ at+ p++iG++ g+d++f G+i ++iy++aL +++i FUN_000533-T1 2913 AQLWHNGKMVKSRNI-GQIQLATQYPIRIGARDGDDRRFSGKISCLQIYDKALDEQQI 2969 *************86.6667799*********************************99 PP >> PLAT PLAT/LH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.8 0.1 7e-25 1.5e-21 1 115 [. 3224 3332 .. 3224 3334 .. 0.92 Alignments for each domain: == domain 1 score: 77.8 bits; conditional E-value: 7e-25 PLAT 1 yqvkvvtgdkkgagtdadvyislygkvgksaqleltldtsgpdfergaedsfevdtdwdlGallkinlhwdnkgisdewflksitvekpgetgk 94 y+v+ tgd +ga t+a+vy++lyg++g+s++ +l++ ++f +g++d+ ++ ++ dlG+l +++ +dn+g ++wfl+++tv+ + e+g+ FUN_000533-T1 3224 YTVSTLTGDMDGADTNANVYVTLYGEKGDSGFRKLET----KHFGKGKNDTSTLILP-DLGKLRQVRILHDNSGTTPSWFLQKLTVT-D-ENGR 3310 89999*******************************9....9**9999999999999.7***************************5.5.5699 PP PLAT 95 kvtFpcnsWvygsksy.ketrv 115 k++Fpc++W+++++ k++r FUN_000533-T1 3311 KYEFPCKEWLSETQGGgKTERL 3332 ************8877777765 PP >> WSC WSC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.9 9.2 3e-19 6.5e-16 2 82 .] 3130 3209 .. 3129 3209 .. 0.94 Alignments for each domain: == domain 1 score: 58.9 bits; conditional E-value: 3e-19 WSC 2 lGCysdssessrlllassasssdmtvekCvaaCk..ekgykyagleygkeCyCgnslpssskkaeeseCntsCsGdsselCGg 82 +GCy+d+ ++ l+ +a+ +++t e Cv+ C+ ekgy+y+gl++++ CyCg+++ ++ k++e+ Cn++C+G+++e CGg FUN_000533-T1 3130 VGCYKDE--ILKHDLPDQATVKSVTQEDCVRSCAmeEKGYSYFGLQNADVCYCGHRYGRYGKADEAL-CNMPCKGNDKENCGG 3209 7****99..689999999***************96678***********************999776.**************8 PP >> PA14 PA14 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.2 3.2e-08 6.8e-05 44 113 .. 2476 2552 .. 2467 2571 .. 0.84 2 ! 30.6 0.0 1.6e-10 3.5e-07 40 115 .. 2637 2719 .. 2612 2740 .. 0.83 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 3.2e-08 PA14 44 ddfsarwtGylkppesGtYtfkiasddgarlfvdgelviDndgkqe........kksfadaspeesktlelvaGkkYp 113 d+ +r Gy+ +pe+G+Ytf ++ ++ +l+ + +n +k + ++++ a + +s++++l+aGk+Y+ FUN_000533-T1 2476 KDYGSRVKGYFVAPETGNYTFYMSGSQSGELWMSSTERQQNLTKLVsmdqptghNQWNKYAGQ-SSRSVNLEAGKYYY 2552 5778999**************************999999999666678888876666666655.56789999999885 PP == domain 2 score: 30.6 bits; conditional E-value: 1.6e-10 PA14 40 seaaddfsarwtGylkppesGtYtfkiasddgarlfvdgelviDndgkqe........kksfadaspeesktlelvaGkkYpir 115 ++d++ +r++G++k+pesG Y f +a+d++ +l++ ++ n +k++ +++ + + + s+++ l +Gk+Y+i+ FUN_000533-T1 2637 HNVDDNYGSRIRGFFKAPESGLYRFFLAADTTGELWLSSDETEKNLKKVVaingwtahNEWL-KFPEQKSDRIHLRKGKYYYIE 2719 567899******************************88777766665666676665544444.456677899**********97 PP >> GLEYA GLEYA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.4 8.7 1.9e+04 24 72 .. 130 180 .. 126 184 .. 0.67 2 ! 25.9 1.1 6.2e-09 1.3e-05 5 70 .. 2482 2551 .. 2478 2556 .. 0.82 3 ! 15.4 0.1 1.1e-05 0.024 4 71 .. 2646 2717 .. 2643 2723 .. 0.81 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 8.7 GLEYA 24 aDdiallwlGdk.Aysgwtranadleatysgssgsksvt.vtltaGtyyPi 72 +++ + + G++ A + +r+++d ++ +++++ + + +t ta + +P+ FUN_000533-T1 130 SNNTVSVKSGEDtATNSTSRTDTDSTKDDTSTTPDITNSdITSTAAQNVPL 180 667777778888788888888888777773333333333488888777776 PP == domain 2 score: 25.9 bits; conditional E-value: 6.2e-09 GLEYA 5 hrGYfyapktgtYtfslsnaDdiallwlGdk.Aysgwtra....nadleatysgssgsksvtvtltaGtyy 70 ++GYf+ap+tg+Ytf + + lw+ ++ ++ t+ + ++++++ +g++s +v+l+aG+yy FUN_000533-T1 2482 VKGYFVAPETGNYTFYM-SGSQSGELWMSSTeRQQNLTKLvsmdQPTGHNQWNKYAGQSSRSVNLEAGKYY 2551 79***************.666777888888856666555554447789999999999*************9 PP == domain 3 score: 15.4 bits; conditional E-value: 1.1e-05 GLEYA 4 nhrGYfyapktgtYtfslsnaDdiallwlGdk.Aysgwtra...na.dleatysgssgsksvtvtltaGtyyP 71 ++rG+f ap++g Y f l aD lwl ++ ++ ++ n +++++ + ++ks +++l +G+yy FUN_000533-T1 2646 RIRGFFKAPESGLYRFFL-AADTTGELWLSSDeTEKNLKKVvaiNGwTAHNEWLKFPEQKSDRIHLRKGKYYY 2717 589***************.9**********996666666665554467778885557888888********95 PP >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 8.7 9.2e-09 2e-05 1 37 [] 527 562 .. 527 562 .. 0.94 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 9.2e-09 ShK 1 sCvDpssdCaswaang.CnspayqdfmkenCpktCgfC 37 +C+D C+++++n C++ + ++mk +C+k+CgfC FUN_000533-T1 527 ECEDQFDTCPEMSKNEyCTKYP--SLMKIQCKKSCGFC 562 5*****************8755..************** PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 6.8 8.7e-09 1.9e-05 1 32 [] 3038 3071 .. 3038 3071 .. 0.96 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 8.7e-09 EGF 1 CspnpCsngGtCvdtp..rggytCiCpeGytGkr 32 C+p pC ngG+C++ + +gy C+C+ +tG++ FUN_000533-T1 3038 CDPKPCENGGKCIRDSrrLDGYRCKCTSDFTGRN 3071 9***********99999***************85 PP >> Chordopox_A33R Chordopoxvirus A33R protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.012 26 98 138 .. 1703 1746 .. 1676 1764 .. 0.77 2 ! 8.7 0.1 0.00065 1.4 111 138 .. 1848 1875 .. 1830 1888 .. 0.90 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.012 Chordopox_A33R 98 vkl.keckGiv..fdsacyrlvkepktfseaskdcakkkaslPa 138 +++ + kG + f s cy+ v e kt+++a c + ++ l + FUN_000533-T1 1703 LQCgAGWKGALgdFGSFCYKEVFERKTWDNAHSTCKNLGGELFS 1746 55555666665447899*******************99988755 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00065 Chordopox_A33R 111 acyrlvkepktfseaskdcakkkaslPa 138 cy+l ke+k++++a +c+++kasl + FUN_000533-T1 1848 GCYKLFKEKKAWEHALVSCMDEKASLAS 1875 6***********************9975 PP >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.2 4.2e+02 65 116 .. 2107 2155 .. 2067 2176 .. 0.71 2 ? 11.3 0.0 0.00013 0.28 81 169 .. 2895 2975 .. 2851 2983 .. 0.79 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.2 Pentaxin 65 yslyvggeevlvkvseeavepvhiCasWesssGivelwvdGkplvkkslkkg 116 y ++ +e + + +++ i ++W+ +G++ l+v+G + slk+g FUN_000533-T1 2107 YKVTTSTKEWQLSTELVTNQWQDIVMTWKKEEGLM-LYVNG--AFRDSLKEG 2155 34444444445555555669999999999999975.89999..555555554 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00013 Pentaxin 81 eavepvhiCasWesssGivelwvdGkplvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykg 169 + +++ + a+++ +G+++lw +Gk +vk + ++ + ++ i +G ++ + G++s l+++d +L +++i ++ ++ FUN_000533-T1 2895 QLNDWNQVGATYDNNTGVAQLWHNGK-MVKSRNIGQIQLATQYPIRIGARD-------GDDRRFSGKISCLQIYDKALDEQQIGSLKSC 2975 4459*********************6.566666667788888888777532.......3467899****************99988766 PP >> PAD Protein-arginine deiminase (PAD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 5.4e-05 0.12 206 265 .. 1835 1895 .. 1822 1908 .. 0.89 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 5.4e-05 PAD 206 ekgf.rlllaspsaalkllqekqkeghgeaklfegkkkekllskekekltinelLadeklv 265 +kg+ +l+l+s + ++kl++ek+ + h ++ +++k++ ++ +++e++ i+++ ++++++ FUN_000533-T1 1835 TKGWeKLTLNSVQGCYKLFKEKKAWEHALVSCMDEKASLASILSDDEQTMISQVYSKSNFW 1895 578845999****************************99***************9999886 PP >> CHU_C CHU_C Type IX secretion signal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 9.3 2e+04 31 52 .. 2096 2117 .. 2091 2122 .. 0.82 2 ? 9.5 0.5 0.00067 1.4 46 78 .. 2530 2562 .. 2525 2568 .. 0.81 3 ? 1.2 0.0 0.27 5.7e+02 54 75 .. 2703 2724 .. 2683 2733 .. 0.70 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 9.3 CHU_C 31 lkiynrwGelVyekknyknewd 52 + ++ ++G+l y+ + ++ew+ FUN_000533-T1 2096 VAVFIKHGSLYYKVTTSTKEWQ 2117 6788899999999999999996 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00067 CHU_C 46 nyknewdGtsngeeklpeGtYfYilklkkgeke 78 n+ n++ G+s+++ +l++G Y+Y++ ++kg+++ FUN_000533-T1 2530 NQWNKYAGQSSRSVNLEAGKYYYTIGVQKGSES 2562 5559999***999*************9665554 PP == domain 3 score: 1.2 bits; conditional E-value: 0.27 CHU_C 54 tsngeeklpeGtYfYilklkkg 75 ++++ +l +G Y+Yi ++k+ FUN_000533-T1 2703 QKSDRIHLRKGKYYYIEAYQKS 2724 334467899*******999544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (3338 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1614 (0.0631826); expected 510.9 (0.02) Passed bias filter: 652 (0.0255236); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.88u 0.46s 00:00:01.34 Elapsed: 00:00:00.45 # Mc/sec: 29766.72 // Query: FUN_000534-T1 [L=368] Description: FUN_000534 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-43 148.6 0.0 5.3e-43 148.0 0.0 1.2 1 Tub Tub family 1.1e-05 26.4 6.2 0.00019 22.3 3.4 2.3 2 Tub_N Tubby N-terminal Domain annotation for each model (and alignments): >> Tub Tub family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 148.0 0.0 4.2e-47 5.3e-43 2 158 .. 210 360 .. 209 366 .. 0.91 Alignments for each domain: == domain 1 score: 148.0 bits; conditional E-value: 4.2e-47 Tub 2 kqpgprdkliqcfikrdksg..kkltstYeLylelseaekgkfLlaarkrrksktseYlisldaedlsrssesyiGklrsnflgtkFtvydkqpps 95 +p+p++++i+c+i+rdk+g +++++tY L++e+ + +k fLla+rkr+ks+ts+Ylis+da+dlsr+ es+iGklrsn++gtkFtv+++ FUN_000534-T1 210 FKPAPQGSPIKCRITRDKKGmdRGMYPTYFLHMEKDDGKKPMFLLAGRKRKKSTTSNYLISTDATDLSRGGESFIGKLRSNLVGTKFTVFNN---- 301 58******************999***********77788888************************************************99.... PP Tub 96 kgakvsksksslkskkvspgryelaavsYelnvlgtrgprrmkvvipsipasaeevpiqpeee 158 g +++k+ s+ ++ r+e+aa++Y++nvlg++gprrm+vv+p++ +++++pi+p++ FUN_000534-T1 302 -GVNPKKGGV--MSDGSNI-REEVAAIIYDTNVLGFKGPRRMTVVLPGMGLDQQRIPIRPHTV 360 .666655544..3444445.9*************************************99876 PP >> Tub_N Tubby N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 3.4 1.5e-08 0.00019 1 43 [. 40 78 .. 40 87 .. 0.84 2 ! 4.5 0.0 0.0044 56 129 169 .. 119 158 .. 79 170 .. 0.67 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 1.5e-08 Tub_N 1 rQRaLlEkKQrkKRqepLMVQaNpdarlRrrrarrseeqaPLV 43 +QR L+ kKQ KR +p MVQaN ar+ +r ++PLV FUN_000534-T1 40 QQRDLMRKKQEMKRAQPGMVQANEVARPMSRHSD----RTPLV 78 8***********************9999766433....35665 PP == domain 2 score: 4.5 bits; conditional E-value: 0.0044 Tub_N 129 eeskkqdlretlekkgisssmnfdeEeedeeeessssssql 169 ++ +d + +l gisss +f + de e s+ +++ FUN_000534-T1 119 RAKQTTDTERKLAAMGISSSADFA-DDLDEPELMSQVIAPA 158 334667888888888********8.5555555555544554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (368 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 548 (0.0214523); expected 510.9 (0.02) Passed bias filter: 426 (0.0166765); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.35s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3666.96 // Query: FUN_000534-T2 [L=356] Description: FUN_000534 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-70 237.9 0.0 2.5e-70 237.6 0.0 1.1 1 Tub Tub family Domain annotation for each model (and alignments): >> Tub Tub family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 237.6 0.0 9.7e-75 2.5e-70 2 211 .. 148 351 .. 147 356 .] 0.93 Alignments for each domain: == domain 1 score: 237.6 bits; conditional E-value: 9.7e-75 Tub 2 kqpgprdkliqcfikrdksg..kkltstYeLylelseaekgkfLlaarkrrksktseYlisldaedlsrssesyiGklrsnflgtkFtvydkqpps 95 +p+p++++i+c+i+rdk+g +++++tY L++e+ + +k fLla+rkr+ks+ts+Ylis+da+dlsr+ es+iGklrsn++gtkFtv+++ FUN_000534-T2 148 FKPAPQGSPIKCRITRDKKGmdRGMYPTYFLHMEKDDGKKPMFLLAGRKRKKSTTSNYLISTDATDLSRGGESFIGKLRSNLVGTKFTVFNN---- 239 58******************999***********77788888************************************************99.... PP Tub 96 kgakvsksksslkskkvspgryelaavsYelnvlgtrgprrmkvvipsipasaeevpiqpeeekesllerlkskrleellvLknkaPrwneqlqay 191 g +++k+ s+ ++ r+e+aa++Y++nvlg++gprrm+vv+p++ +++++pi+p+++++ ller+k+kr+e+ll+L+nk+P wn+++q+y FUN_000534-T2 240 -GVNPKKGGV--MSDGSNI-REEVAAIIYDTNVLGFKGPRRMTVVLPGMGLDQQRIPIRPHTDNDGLLERHKNKRMENLLELHNKTPVWNDDTQSY 331 .666655544..3444445.9*******************************************99****************************** PP Tub 192 vLnFrgRvtvaSvKNFqLva 211 vLnF+gRvt+aSvKNFq+v FUN_000534-T2 332 VLNFHGRVTQASVKNFQIVM 351 *******************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (356 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 438 (0.0171462); expected 510.9 (0.02) Passed bias filter: 398 (0.0155803); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.43s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3535.17 // Query: FUN_000535-T1 [L=311] Description: FUN_000535 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-09 38.1 0.2 1.2e-09 38.1 0.2 2.1 3 MBD Methyl-CpG binding domain ------ inclusion threshold ------ 0.067 13.2 1.8 0.16 11.9 1.8 1.7 1 zf-C2H2_FBX41 F-box only protein 41 C2H2 zinc finger Domain annotation for each model (and alignments): >> MBD Methyl-CpG binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.1 0.2 9.3e-14 1.2e-09 13 72 .. 16 73 .. 13 78 .. 0.89 2 ? -3.1 0.5 0.72 9.1e+03 16 27 .. 150 161 .. 150 166 .. 0.77 3 ? -3.0 0.0 0.66 8.4e+03 51 71 .. 205 224 .. 197 226 .. 0.66 Alignments for each domain: == domain 1 score: 38.1 bits; conditional E-value: 9.3e-14 MBD 13 kGWrretrqrksGskagkvdviYysPtGkklrsksevarYLekngdvtslkledFsftar 72 +GW++ + qr+sG++ g+ dv+ + P+G+++rs e+ r++++ + + ++ +f+++ FUN_000535-T1 16 AGWKKIVTQRQSGKSKGRYDVYIVNPSGRRFRSLVELRRFMSAEHR--DFSFKNVDFKVP 73 69****************************************9986..777777777665 PP == domain 2 score: -3.1 bits; conditional E-value: 0.72 MBD 16 rretrqrksGsk 27 +re+++rks s+ FUN_000535-T1 150 KREVKRRKSSSQ 161 799999998654 PP == domain 3 score: -3.0 bits; conditional E-value: 0.66 MBD 51 rYLekngdvtslkledFsfta 71 + ++++ +lk +d+sf++ FUN_000535-T1 205 NCVSNAN-HLKLKSDDCSFDN 224 5555555.3678889999986 PP >> zf-C2H2_FBX41 F-box only protein 41 C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 1.8 1.3e-05 0.16 12 28 .. 44 60 .. 42 62 .. 0.88 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 1.3e-05 zf-C2H2_FBX41 12 kRFrSLssLRaHLeysH 28 +RFrSL +LR+ + H FUN_000535-T1 44 RRFRSLVELRRFMSAEH 60 8*********9998888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (311 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1586 (0.0620865); expected 510.9 (0.02) Passed bias filter: 655 (0.025641); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.43s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3122.74 // Query: FUN_000536-T1 [L=992] Description: FUN_000536 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-85 285.3 2.6 1.4e-84 284.6 2.0 1.7 2 GCP_N_terminal Gamma tubulin complex component N-terminal 2.4e-82 277.4 9.2 2.4e-82 277.4 9.2 1.9 2 GCP_C_terminal Gamma tubulin complex component C-terminal ------ inclusion threshold ------ 0.25 11.4 1.1 0.65 10.1 1.1 1.7 1 zf-Tim10_DDP Tim10/DDP family zinc finger Domain annotation for each model (and alignments): >> GCP_N_terminal Gamma tubulin complex component N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 284.6 2.0 1.7e-88 1.4e-84 1 297 [] 229 529 .. 229 529 .. 0.92 2 ? -3.0 0.0 0.68 5.8e+03 271 294 .. 864 887 .. 836 889 .. 0.72 Alignments for each domain: == domain 1 score: 284.6 bits; conditional E-value: 1.7e-88 GCP_N_terminal 1 lrdllfllqGisgkyirfdesds.rivkdlripsvlppslrellsellelgtlyrrlrkfveeksssesglvlqalcaalqeeLteyyrliaqle 94 ++dllfl++Gi+gky+ +++ ++ ++++i+++l s+ el++++l+++++y+ + +++e kss+e+glv++alcaa++++L+ey+ l+aqle FUN_000536-T1 229 VEDLLFLMMGIEGKYLLVKPLKDkFNPRSFTIDKTLETSMLELVQRILPVCSHYSTICRYMEGKSSFEHGLVNHALCAAMRTLLKEYLILVAQLE 323 68**************7777454344567999*************************************************************** PP GCP_N_terminal 95 sqlleaskeiltLkrlvvwlqealerlrllsnlveevekqnlkggallsllheats..hGdpfvrellerlleevskpylemlekWileGeldDp 187 +q++ ++ l+L++l++++q++l ++++ls++v +++k+++kgga+l+llhe+t +Gd++ ++l+ l++++++py+++le+Wi++G ++Dp FUN_000536-T1 324 HQFRLGQ---LSLQKLWFYVQPCLRTMEILSSIVMAIDKASCKGGAVLTLLHEKTVgyTGDSKSQDLCLFLTQAACVPYFDILEQWIYKGIISDP 415 ******9...*******************************************77778************************************* PP GCP_N_terminal 188 ynEFFveeneeeakeeltee..........sssdlweekYelrkemlPsflspelaekIlstGKslnflrescgdsewveetaseley.gdslss 271 y+EF+v+e+ +++ke++ + ++we++Y++ +e++P fl++ +a+kIlstGK+ln++r++ ++ + + +a+e+ y ++ + FUN_000536-T1 416 YSEFLVAEHGSVQKEKTIAVskflseivslNIRKYWEQRYTVVRENIPIFLEK-VAHKILSTGKYLNVIRQCGQNVQ-CP-NADEIIYtLH-E-- 504 ************9886655599********999********************.*****************766666.66.3444566344.3.. PP GCP_N_terminal 272 slsleelIdsayklaskrllelllee 297 +++ e I++ay +ask+ll+ll++e FUN_000536-T1 505 -REYVEKIEKAYGYASKTLLDLLMDE 529 .47*********************98 PP == domain 2 score: -3.0 bits; conditional E-value: 0.68 GCP_N_terminal 271 sslsleelIdsayklaskrllell 294 s +++e+ I++ + s +l++ll FUN_000536-T1 864 SGEDFERTIQNFDNNFSLHLMDLL 887 267899999999999999999998 PP >> GCP_C_terminal Gamma tubulin complex component C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 0.23 2e+03 218 279 .. 265 321 .. 255 339 .. 0.60 2 ! 277.4 9.2 2.8e-86 2.4e-82 1 309 [] 532 915 .. 532 915 .. 0.94 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.23 GCP_C_terminal 218 qekllklleeilelilkFaealdrlylslsesaeeeeeeeleeeleerlkelekkFrkkvse 279 ++++l+l+++il ++ +++ + + ++ +s++ e+ +++ l + +++l k++ v++ FUN_000536-T1 265 ETSMLELVQRILPVCSHYSTICRY-MEGKSSF----EHGLVNHALCAAMRTLLKEYLILVAQ 321 668999999999999999875433.2333332....23344444445555555555444444 PP == domain 2 score: 277.4 bits; conditional E-value: 2.8e-86 GCP_C_terminal 1 LldhLkalkrylLLgqGdFisrLmealfdelwkpasselrlnLtslLeealrssnaeqsdelkddlsfaldlpevleeldarlepds........ 87 L+d+L+++k+y+L++ GdF+ ++m++++de++k++++++ L++lLe+alr+s+a +sd++kddl+++l +++++++l ++l++ FUN_000536-T1 532 LMDRLRSIKHYFLMDLGDFFVQFMDLAEDEMKKNMDDIMPSRLENLLELALRTSTA-NSDPYKDDLRVDLLPYDLITQLFRILSVAYdsratmap 625 9************************************99999***********987.66********************9766664478****** PP GCP_C_terminal 88 ...................................lggldfltLeYkvpwplslvltpealekYqrlfrfLlrlkrvefalssvw....kkrkak 143 ++gl++++++Y v+wp+sl+l+++al+kYq+lfr+L++ ++ve++l++vw +++ ++ FUN_000536-T1 626 lamkkvlkaealrrpfekasssgattynqdptelqISGLEAFSFDYVVKWPVSLILSKKALTKYQMLFRHLFYARHVERQLCNVWvsnkRAKLFT 720 *********************************9999************************************************8765555555 PP GCP_C_terminal 144 ssrsvllkkarllraemlhfvsqlqyYvlfeviepsWkeleeklkkkasdldelieaHekfLdrilkkllLtkkqekllklleeilelilkFaea 238 ++s++++ a++lr++mlhfv+++++Y++fev+epsW+ +e+++k+ ++++d ++e H++fLdr+lk+++Lt++ +llk +++++ ++++F+++ FUN_000536-T1 721 LNSSHWYAAAFALRQRMLHFVQTYEHYMMFEVLEPSWHLMEKSFKT-VTNIDGVLENHNDFLDRCLKDCMLTNP--ELLKVVSKLMLVCVTFTNC 812 6667789999**********************************75.555************************..******************* PP GCP_C_terminal 239 ldrly.lslsesa..............................eee.eeeeleeeleerlkelekkFrkkvsellkvlralkeskdeedlrqLll 301 ++r++ +++ es+ +e+ ++ e++e+++++++++F+ ++ +ll++l+++++ + e+++ +++ FUN_000536-T1 813 MQRFTqSATVESQeiiapgvgvmskkgpppdeqekkkatvkviSEHvDQMISGEDFERTIQNFDNNFSLHLMDLLEKLSHYSTIDCEHQMLNIIA 907 ***99766666669****************************977756666666999************************9999********** PP GCP_C_terminal 302 rLdfneyY 309 rLd n++Y FUN_000536-T1 908 RLDHNGFY 915 *******9 PP >> zf-Tim10_DDP Tim10/DDP family zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 1.1 7.6e-05 0.65 9 57 .. 770 822 .. 763 829 .. 0.76 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 7.6e-05 zf-Tim10_DDP 9 lanfqelvnkltekCfkkCi.tk.fpsssLssgEesCl..dnCvekfldasnr 57 ++ + e n + ++C k+C+ t+ + +s+ +C+ +nC+++f ++ ++ FUN_000536-T1 770 IDGVLENHNDFLDRCLKDCMlTNpELLKVVSKLMLVCVtfTNCMQRFTQSATV 822 566788899***********5331244778888889*8556******998766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (992 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1026 (0.0401644); expected 510.9 (0.02) Passed bias filter: 671 (0.0262674); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.44u 0.38s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 9554.94 // Query: FUN_000537-T1 [L=880] Description: FUN_000537 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-44 146.3 16.9 1.9e-07 31.1 0.0 9.2 9 TPR_1 Tetratricopeptide repeat 3.4e-43 142.7 16.5 2.5e-05 24.5 0.0 9.4 9 TPR_2 Tetratricopeptide repeat 3.7e-37 123.8 12.7 0.0001 22.6 0.0 9.4 9 TPR_8 Tetratricopeptide repeat 7.8e-33 112.4 10.5 8.2e-08 32.3 0.1 8.7 9 TPR_11 TPR repeat 1.5e-31 108.6 0.8 4.9e-31 107.0 0.8 1.9 1 TMTC_DUF1736 Protein O-mannosyl-transferase TMTC, DUF17 6e-31 107.0 7.7 5.8e-09 36.7 0.1 6.0 6 TPR_16 Tetratricopeptide repeat 6.1e-31 106.9 19.2 1.3e-06 29.0 0.0 7.2 6 TPR_12 Tetratricopeptide repeat 9.2e-26 88.2 6.3 0.0064 17.0 0.0 9.2 9 TPR_7 Tetratricopeptide repeat 1.5e-24 86.6 13.2 5.5e-06 27.1 0.2 6.4 6 TPR_19 Tetratricopeptide repeat 1.2e-23 81.7 15.4 8.6e-05 23.4 0.1 9.2 9 TPR_14 Tetratricopeptide repeat 1.9e-23 81.2 14.5 1.8e-05 25.1 0.1 9.4 9 TPR_17 Tetratricopeptide repeat 4.3e-22 77.9 21.5 0.00016 22.0 0.4 9.3 9 TPR_10 Tetratricopeptide repeat 2.6e-15 57.1 6.2 4.6e-08 33.5 0.4 4.3 3 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR 9.1e-11 42.6 11.2 0.03 15.2 0.0 5.6 6 TPR_Slam Surface lipoprotein assembly modifier, N-t 9.3e-11 42.4 2.0 5.4e-07 30.3 0.4 3.4 3 HAT_PRP39_C PRP39 C-terminal HAT repeat 7.1e-09 36.3 11.6 0.0027 18.5 0.5 5.2 6 ANAPC3 Anaphase-promoting complex, cyclosome, sub 8.5e-08 32.6 2.3 0.014 15.9 0.0 4.5 4 TPR_9 Tetratricopeptide repeat 1.1e-07 32.6 1.5 0.095 13.4 0.0 4.1 3 TPR_5 Tetratrico peptide repeat 3.8e-07 30.7 5.5 0.13 12.7 0.0 4.5 4 ARM_TT21 Tetratricopeptide repeat protein 21 ARM re 1.1e-06 29.2 0.0 4.1 8.8 0.0 5.7 4 TPR_4 Tetratricopeptide repeat 1.1e-06 28.7 3.7 0.0079 16.0 0.2 3.3 4 TPR_MalT MalT-like TPR region 2.3e-06 27.7 11.6 0.0007 19.6 3.6 3.7 4 TPR_15 Tetratricopeptide repeat 4.2e-06 26.7 4.0 0.055 13.2 0.1 3.7 3 FAT FAT domain 5.3e-06 26.1 6.9 0.01 15.3 0.3 3.6 4 NatA_aux_su N-terminal acetyltransferase A, auxiliary 6.1e-06 26.8 6.1 0.011 16.2 1.1 4.5 4 DUF7017 Domain of unknown function (DUF7017) 3.7e-05 23.0 2.6 0.0023 17.0 0.1 3.2 3 Suf Suppressor of forked protein (Suf) 7.3e-05 23.7 16.4 8.3 7.8 0.0 8.5 9 TPR_6 Tetratricopeptide repeat 7.8e-05 23.1 7.0 0.029 14.7 0.1 3.5 3 ARM_TT21_C Tetratricopeptide repeat protein 21 C-term 8.8e-05 22.4 4.0 0.23 11.2 0.1 4.0 4 T7SS_EccA1_N T7SS, ESX-1 secretion system protein EccA1 0.00011 22.5 8.1 2.3 8.4 0.0 5.2 5 TPR_21 Tetratricopeptide repeat-like domain 0.00026 21.3 0.3 0.0035 17.6 0.1 2.7 3 HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-ter 0.00058 19.2 3.3 0.81 8.8 0.3 3.8 4 HAT_Syf1_CNRKL1_C Pre-mRNA-splicing factor Syf1/CRNKL1 C-ter 0.00062 20.6 2.6 2.1 9.2 0.0 3.9 4 ARM_TT21_5th TT21 fifth ARM repeats domain 0.001 19.1 2.5 1.4 8.8 0.1 4.2 4 ARM_TT21_2nd Tetratricopeptide repeat protein 21 second 0.0059 16.8 1.9 0.44 10.7 0.5 2.7 2 ARM_TT21_N Tetratricopeptide repeat protein 21 N-term 0.0073 16.2 10.5 0.23 11.3 0.2 3.8 4 TPR_NPHP3 Nephrocystin-3 TPR domain ------ inclusion threshold ------ 0.022 15.8 1.1 0.32 12.1 0.1 3.1 2 TPPII_C Tripeptidyl peptidase II, C-terminal 0.036 14.9 6.2 59 4.6 0.6 5.2 4 TPR_20 Tetratricopeptide repeat 0.067 13.9 5.8 28 5.7 0.0 5.0 4 PPR PPR repeat 0.082 13.3 4.2 0.12 12.8 0.2 2.8 2 TPR_TmcB TmcB, TPR repeats 0.14 12.9 11.4 1.2 9.8 0.0 6.0 6 TPR_3 Tetratricopeptide repeat 0.16 12.5 0.1 0.55 10.8 0.1 1.8 1 HAT_PRP39_N PRP39 N-terminal HAT repeat 1.8 8.5 15.2 0.47 10.3 0.8 3.6 2 SNAP Soluble NSF attachment protein, SNAP 3.8 8.0 9.3 8.5 6.9 0.5 4.6 5 TPR_WDR35 WD repeat-containing protein 35, TPR repea 4.9 8.4 5.6 31 5.8 0.1 3.9 2 Sel1 Sel1 repeat Domain annotation for each model (and alignments): >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.1 6.3e-09 3.6e-06 1 31 [. 538 568 .. 538 571 .. 0.93 2 ! 24.4 0.0 4.3e-08 2.4e-05 1 32 [. 572 603 .. 572 605 .. 0.95 3 ! 14.1 0.0 7.7e-05 0.044 1 27 [. 606 632 .. 606 635 .. 0.90 4 ! 15.3 0.0 3.1e-05 0.018 5 32 .. 655 682 .. 651 684 .. 0.90 5 ! 8.7 0.2 0.0039 2.2 4 34 .] 691 721 .. 689 721 .. 0.91 6 ! 11.5 0.9 0.00052 0.3 11 33 .. 732 754 .. 729 755 .. 0.90 7 ? 0.2 0.0 1.9 1.1e+03 3 34 .] 758 789 .. 756 789 .. 0.85 8 ! 15.4 0.9 3e-05 0.017 13 34 .] 802 823 .. 799 823 .. 0.91 9 ! 31.1 0.0 3.3e-10 1.9e-07 2 33 .. 825 856 .. 824 857 .. 0.95 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 6.3e-09 TPR_1 1 akalynlGnayfklgkydeAleyyekALeln 31 akal nlGn++ ++++ eA+++y+kAL+ + FUN_000537-T1 538 AKALSNLGNVLSSQKRKREAEDAYRKALSYR 568 89**************************866 PP == domain 2 score: 24.4 bits; conditional E-value: 4.3e-08 TPR_1 1 akalynlGnayfklgkydeAleyyekALelnP 32 a+++ynlG ++ + +++ eA++ ye A+ +P FUN_000537-T1 572 ADTHYNLGILLAEEKRFSEAVQSYENAIHFRP 603 799*************************9988 PP == domain 3 score: 14.1 bits; conditional E-value: 7.7e-05 TPR_1 1 akalynlGnayfklgkydeAleyyekA 27 a a+ nlG ++ +g +++Al+ + A FUN_000537-T1 606 AAAHLNLGIVLSDMGHFEKALKVLRTA 632 789******************977665 PP == domain 4 score: 15.3 bits; conditional E-value: 3.1e-05 TPR_1 5 ynlGnayfklgkydeAleyyekALelnP 32 ynlG ++ +lgk +eA+ y A+e +P FUN_000537-T1 655 YNLGRILAQLGKMEEAISVYLDAVETRP 682 9*****************9999998777 PP == domain 5 score: 8.7 bits; conditional E-value: 0.0039 TPR_1 4 lynlGnayfklgkydeAleyyekALelnPnn 34 ++ lG ay + g +eA+ +y++ L+ P++ FUN_000537-T1 691 FNMLGEAYSAAGYQNEAERCYKESLKSKPDH 721 67899999999999************99986 PP == domain 6 score: 11.5 bits; conditional E-value: 0.00052 TPR_1 11 yfklgkydeAleyyekALelnPn 33 + k+gk eA++ ++kA +l+ n FUN_000537-T1 732 LNKMGKIAEAEKLFKKAQRLDAN 754 679*****************977 PP == domain 7 score: 0.2 bits; conditional E-value: 1.9 TPR_1 3 alynlGnayfklgkydeAleyyekALelnPnn 34 a+ G+ +f ++ eA + kA l P++ FUN_000537-T1 758 AWTHYGQFLFDRKRVTEAASMFAKAMVLAPED 789 56666888999**************9999975 PP == domain 8 score: 15.4 bits; conditional E-value: 3e-05 TPR_1 13 klgkydeAleyyekALelnPnn 34 + gk ++A+++y+kA el+P+n FUN_000537-T1 802 EIGKNQQAEDCYKKAAELQPQN 823 67999***************97 PP == domain 9 score: 31.1 bits; conditional E-value: 3.3e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALelnPn 33 a+ nlG++++ +gk+deA++ y +AL+l P FUN_000537-T1 825 AAHMNLGAMFHMQGKLDEAEKSYVRALQLKPG 856 69****************************97 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.2 4.7e-07 0.00026 1 30 [. 538 567 .. 538 570 .. 0.94 2 ! 18.5 0.0 3.9e-06 0.0022 1 32 [. 572 603 .. 572 605 .. 0.92 3 ! 14.5 0.0 7.1e-05 0.04 1 27 [. 606 632 .. 606 636 .. 0.93 4 ! 15.2 0.0 4.2e-05 0.024 5 32 .. 655 682 .. 652 684 .. 0.91 5 ! 16.6 0.1 1.5e-05 0.0087 4 34 .] 691 721 .. 688 721 .. 0.93 6 ! 10.1 0.3 0.0018 1 13 33 .. 734 754 .. 724 755 .. 0.83 7 ! 10.2 0.0 0.0017 0.96 1 34 [] 756 789 .. 756 789 .. 0.95 8 ! 14.2 0.4 9.4e-05 0.053 7 34 .] 796 823 .. 790 823 .. 0.86 9 ! 24.5 0.0 4.5e-08 2.5e-05 1 34 [] 824 857 .. 824 857 .. 0.95 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 4.7e-07 TPR_2 1 aealynlGlayyklgdyeeAleayekAlel 30 a+al nlG+++ +++ eA++ay+kAl++ FUN_000537-T1 538 AKALSNLGNVLSSQKRKREAEDAYRKALSY 567 79**************************87 PP == domain 2 score: 18.5 bits; conditional E-value: 3.9e-06 TPR_2 1 aealynlGlayyklgdyeeAleayekAleldP 32 a+ +ynlG ++++ +++ eA++ ye A+ P FUN_000537-T1 572 ADTHYNLGILLAEEKRFSEAVQSYENAIHFRP 603 689************************97766 PP == domain 3 score: 14.5 bits; conditional E-value: 7.1e-05 TPR_2 1 aealynlGlayyklgdyeeAleayekA 27 a+a+ nlG ++ +g++e+Al+ ++ A FUN_000537-T1 606 AAAHLNLGIVLSDMGHFEKALKVLRTA 632 689********************9988 PP == domain 4 score: 15.2 bits; conditional E-value: 4.2e-05 TPR_2 5 ynlGlayyklgdyeeAleayekAleldP 32 ynlG+++++lg+ eeA+ y A+e P FUN_000537-T1 655 YNLGRILAQLGKMEEAISVYLDAVETRP 682 9**********************99777 PP == domain 5 score: 16.6 bits; conditional E-value: 1.5e-05 TPR_2 4 lynlGlayyklgdyeeAleayekAleldPnn 34 ++lG+ay ++g +eA+++y+++l+ P++ FUN_000537-T1 691 FNMLGEAYSAAGYQNEAERCYKESLKSKPDH 721 689***********************99986 PP == domain 6 score: 10.1 bits; conditional E-value: 0.0018 TPR_2 13 klgdyeeAleayekAleldPn 33 k+g+ +eA+++++kA +ld n FUN_000537-T1 734 KMGKIAEAEKLFKKAQRLDAN 754 89****************977 PP == domain 7 score: 10.2 bits; conditional E-value: 0.0017 TPR_2 1 aealynlGlayyklgdyeeAleayekAleldPnn 34 ++a+ G+ ++ +++ eA+ + kA l+P++ FUN_000537-T1 756 PAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPED 789 579*****************************86 PP == domain 8 score: 14.2 bits; conditional E-value: 9.4e-05 TPR_2 7 lGlayyklgdyeeAleayekAleldPnn 34 + +++ g+ ++A+++y+kA el+P+n FUN_000537-T1 796 AAGYLREIGKNQQAEDCYKKAAELQPQN 823 56678899******************97 PP == domain 9 score: 24.5 bits; conditional E-value: 4.5e-08 TPR_2 1 aealynlGlayyklgdyeeAleayekAleldPnn 34 ++a++nlG ++g+++eA++ y +Al+l P++ FUN_000537-T1 824 PAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPGD 857 579****************************985 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.2 4.4e-06 0.0025 1 32 [. 538 569 .. 538 571 .. 0.93 2 ! 12.0 0.0 0.00047 0.26 1 28 [. 572 599 .. 572 604 .. 0.91 3 ! 10.9 0.0 0.001 0.59 2 30 .. 607 635 .. 606 637 .. 0.90 4 ! 22.6 0.0 1.8e-07 0.0001 3 32 .. 653 682 .. 651 684 .. 0.91 5 ! 17.4 0.1 8.5e-06 0.0048 3 34 .] 690 721 .. 688 721 .. 0.94 6 ! 12.7 0.2 0.00028 0.16 4 34 .] 725 755 .. 722 755 .. 0.89 7 ? 3.9 0.0 0.19 1.1e+02 3 33 .. 758 788 .. 756 789 .. 0.91 8 ! 12.9 0.2 0.00024 0.13 10 34 .] 799 823 .. 791 823 .. 0.88 9 ! 12.0 0.0 0.00048 0.27 3 33 .. 826 856 .. 824 857 .. 0.90 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 4.4e-06 TPR_8 1 aeayynlGliylklgdyeeAkeyyekaleldp 32 a+a+ nlG+++++++++ eA+ +y+kal+++ FUN_000537-T1 538 AKALSNLGNVLSSQKRKREAEDAYRKALSYRS 569 68999***********************9876 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00047 TPR_8 1 aeayynlGliylklgdyeeAkeyyekal 28 a+++ynlG ++ + +++ eA+++ye a+ FUN_000537-T1 572 ADTHYNLGILLAEEKRFSEAVQSYENAI 599 6789*********************998 PP == domain 3 score: 10.9 bits; conditional E-value: 0.001 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 a++nlG +++++g +e+A ++++ a ++ FUN_000537-T1 607 AAHLNLGIVLSDMGHFEKALKVLRTASTI 635 6899********************99766 PP == domain 4 score: 22.6 bits; conditional E-value: 1.8e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 + ynlG+i+ +lg++eeA+ +y a+e +p FUN_000537-T1 653 IKYNLGRILAQLGKMEEAISVYLDAVETRP 682 67************************9988 PP == domain 5 score: 17.4 bits; conditional E-value: 8.5e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldpdn 34 + ++lG +y+ g+ +eA+ +y+++l+ +pd+ FUN_000537-T1 690 LFNMLGEAYSAAGYQNEAERCYKESLKSKPDH 721 679***************************97 PP == domain 6 score: 12.7 bits; conditional E-value: 0.00028 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldpdn 34 ++ +++ + k+g+++eA++ ++ka +ld+++ FUN_000537-T1 725 HLTYAKYLNKMGKIAEAEKLFKKAQRLDAND 755 567889999*******************985 PP == domain 7 score: 3.9 bits; conditional E-value: 0.19 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldpd 33 a+ ++G+ + + ++ eA + ka l+p+ FUN_000537-T1 758 AWTHYGQFLFDRKRVTEAASMFAKAMVLAPE 788 89***********************988876 PP == domain 8 score: 12.9 bits; conditional E-value: 0.00024 TPR_8 10 iylklgdyeeAkeyyekaleldpdn 34 +++ g+ ++A+ +y+ka el+p+n FUN_000537-T1 799 YLREIGKNQQAEDCYKKAAELQPQN 823 56889******************97 PP == domain 9 score: 12.0 bits; conditional E-value: 0.00048 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldpd 33 a++nlG + +g+++eA+++y +al+l+p FUN_000537-T1 826 AHMNLGAMFHMQGKLDEAEKSYVRALQLKPG 856 67899999999******************95 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 1.5 8.7e+02 27 39 .. 537 549 .. 536 552 .. 0.82 2 ! 19.0 0.2 2e-06 0.0012 1 39 [. 545 583 .. 545 586 .. 0.88 3 ! 26.7 0.0 8.2e-09 4.7e-06 5 42 .] 583 620 .. 580 620 .. 0.92 4 ? 1.6 0.0 0.57 3.2e+02 7 23 .. 619 635 .. 616 636 .. 0.86 5 ! 12.1 0.0 0.0003 0.17 1 25 [. 658 682 .. 658 689 .. 0.92 6 ? 1.9 0.0 0.46 2.6e+02 1 26 [. 695 720 .. 695 725 .. 0.92 7 ! 9.9 0.1 0.0014 0.81 6 36 .. 734 764 .. 730 769 .. 0.89 8 ! 32.3 0.1 1.4e-10 8.2e-08 5 42 .] 801 838 .. 800 838 .. 0.96 9 ! 12.7 0.0 0.00019 0.11 4 25 .. 834 855 .. 832 857 .. 0.92 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 1.5 TPR_11 27 naeayynLGlayy 39 a a++nLG+++ FUN_000537-T1 537 AAKALSNLGNVLS 549 6899******986 PP == domain 2 score: 19.0 bits; conditional E-value: 2e-06 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayy 39 G+++ +q + eA aY+kAl ++++ a+ +ynLG +++ FUN_000537-T1 545 GNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLA 583 677777777789999********************9876 PP == domain 3 score: 26.7 bits; conditional E-value: 8.2e-09 TPR_11 5 yeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 e ++ eA+++Y++A+ ++P a a++nLG ++ +G FUN_000537-T1 583 AEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMG 620 567899***************************98887 PP == domain 4 score: 1.6 bits; conditional E-value: 0.57 TPR_11 7 qGkyeeAieaYkkAlkl 23 G +e+A++++++A + FUN_000537-T1 619 MGHFEKALKVLRTASTI 635 7999*********9876 PP == domain 5 score: 12.1 bits; conditional E-value: 0.0003 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldP 25 G+++ ++Gk eeAi +Y A++ +P FUN_000537-T1 658 GRILAQLGKMEEAISVYLDAVETRP 682 89******************99776 PP == domain 6 score: 1.9 bits; conditional E-value: 0.46 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPd 26 G ay + G +eA +Yk+ lk +Pd FUN_000537-T1 695 GEAYSAAGYQNEAERCYKESLKSKPD 720 7899999999************9998 PP == domain 7 score: 9.9 bits; conditional E-value: 0.0014 TPR_11 6 eqGkyeeAieaYkkAlkldPdnaeayynLGl 36 + Gk+ eA + +kkA +ld +++ a+ + G+ FUN_000537-T1 734 KMGKIAEAEKLFKKAQRLDANDPAAWTHYGQ 764 78***********************988776 PP == domain 8 score: 32.3 bits; conditional E-value: 1.4e-10 TPR_11 5 yeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 +e Gk+ +A +YkkA +l P+n+ a+ nLG+ +++qG FUN_000537-T1 801 REIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQG 838 788*********************************99 PP == domain 9 score: 12.7 bits; conditional E-value: 0.00019 TPR_11 4 yyeqGkyeeAieaYkkAlkldP 25 ++ qGk++eA ++Y +Al+l+P FUN_000537-T1 834 FHMQGKLDEAEKSYVRALQLKP 855 6779****************99 PP >> TMTC_DUF1736 Protein O-mannosyl-transferase TMTC, DUF1736 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.0 0.8 8.7e-34 4.9e-31 2 74 .. 279 351 .. 278 352 .. 0.97 Alignments for each domain: == domain 1 score: 107.0 bits; conditional E-value: 8.7e-34 TMTC_DUF1736 2 selPkFsesdnPaafseslltRaltynYllvlnlwlLllPssLsfDWsmgsipliesllDpRnlatllfylvl 74 +++P+Fs sdnP a+se++ltR lt+ Yl+v+n+wlL++P++LsfDWsm+s+pl+esllD+R++++l+fy+++ FUN_000537-T1 279 KQAPNFSPSDNPSANSEKFLTRLLTFVYLPVFNFWLLVCPRTLSFDWSMESVPLVESLLDVRCAIILMFYGFF 351 799*******************************************************************987 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.2 9.6e-08 5.4e-05 3 60 .. 544 601 .. 542 606 .. 0.90 2 ? 2.7 0.0 0.46 2.6e+02 1 23 [. 610 632 .. 610 634 .. 0.91 3 ! 15.6 0.0 4.3e-05 0.024 34 62 .. 654 682 .. 652 685 .. 0.90 4 ! 12.7 0.1 0.00034 0.19 2 65 .] 693 756 .. 692 756 .. 0.93 5 ! 26.2 0.4 2e-08 1.2e-05 7 63 .. 732 788 .. 726 790 .. 0.89 6 ! 36.7 0.1 1e-11 5.8e-09 6 64 .. 799 857 .. 794 858 .. 0.93 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 9.6e-08 TPR_16 3 laraalaagdyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalra 60 l++ + + + ++A+ a++ al ++ a+ +++lG +l++ +r+ eA++ y+ a+ FUN_000537-T1 544 LGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAIHF 601 78889999999**************************************999877655 PP == domain 2 score: 2.7 bits; conditional E-value: 0.46 TPR_16 1 lalaraalaagdyddAaaaleaa 23 l l+ + ++g+++ A++ l++a FUN_000537-T1 610 LNLGIVLSDMGHFEKALKVLRTA 632 578999**************987 PP == domain 3 score: 15.6 bits; conditional E-value: 4.3e-05 TPR_16 34 llglGlallrqgrlaeAaaayraalraap 62 ++lG++l+++g+++eA+ +y a++ p FUN_000537-T1 654 KYNLGRILAQLGKMEEAISVYLDAVETRP 682 69**********************98777 PP == domain 4 score: 12.7 bits; conditional E-value: 0.00034 TPR_16 2 alaraalaagdyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalraapgdp 65 +l+ a+ aag +A++++++ l++ P++ +l ++ l + g+ aeA++++++a+r++++dp FUN_000537-T1 693 MLGEAYSAAGYQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDP 756 67777788888889**********************************************9998 PP == domain 5 score: 26.2 bits; conditional E-value: 2e-08 TPR_16 7 alaagdyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalraapg 63 + ++g+ ++A+++++ a r + ++aA+ +G+ l++++r++eAa +++a +ap FUN_000537-T1 732 LNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPE 788 5589*****************************************988888667665 PP == domain 6 score: 36.7 bits; conditional E-value: 1e-11 TPR_16 6 aalaagdyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalraapgd 64 ++++ g++++A+ +++ a++ +P+++aA+++lG +++ qg+l+eA++ y +al++ pgd FUN_000537-T1 799 YLREIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPGD 857 67889*****************************************88888899*9997 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.2 5e-06 0.0028 43 73 .. 536 566 .. 535 570 .. 0.92 2 ! 24.8 0.2 4.7e-08 2.7e-05 2 74 .. 571 635 .. 570 636 .. 0.88 3 ! 29.0 0.0 2.2e-09 1.3e-06 3 74 .. 651 717 .. 649 720 .. 0.93 4 ! 7.9 0.1 0.0088 5 8 32 .. 727 751 .. 721 756 .. 0.76 5 ! 18.2 0.3 5.2e-06 0.0029 4 75 .. 757 820 .. 754 822 .. 0.91 6 ! 15.3 0.1 4.4e-05 0.025 5 32 .. 826 853 .. 822 859 .. 0.77 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 5e-06 TPR_12 43 ltatalrnLgrlylalgdyeeAlelleqale 73 + a al nLg +++ +++ +eA++++++al FUN_000537-T1 536 NAAKALSNLGNVLSSQKRKREAEDAYRKALS 566 5799*************************97 PP == domain 2 score: 24.8 bits; conditional E-value: 4.7e-08 TPR_12 2 tatalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +a +++nl+ +l++ +r+ eA + +e+a+ + p +a+a+ nLg++++ +g++e+Al+ l+ a i FUN_000537-T1 571 MADTHYNLGILLAEEKRFSEAVQSYENAIHFR--------PRLAAAHLNLGIVLSDMGHFEKALKVLRTASTI 635 68889999999999999999999999988666........559************************999765 PP == domain 3 score: 29.0 bits; conditional E-value: 2.2e-09 TPR_12 3 atalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 ++ +nl+ +l++lg+++eA++ + a+e + p h + + Lg++y+a+g + eA+++++++l+ FUN_000537-T1 651 ISIKYNLGRILAQLGKMEEAISVYLDAVETR-----PPHYEPHSLFNMLGEAYSAAGYQNEAERCYKESLKS 717 56778**************************.....99999999*************************985 PP == domain 4 score: 7.9 bits; conditional E-value: 0.0088 TPR_12 8 nlAavlrrlgrydeAlellekalel 32 +A l ++g+ +eA++l++ka +l FUN_000537-T1 727 TYAKYLNKMGKIAEAEKLFKKAQRL 751 5677788888888888888888765 PP == domain 5 score: 18.2 bits; conditional E-value: 5.2e-06 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ +++++l++++r +eA +++ ka+ la p++ ++++ + ++++ g+ ++A++++++a e+ FUN_000537-T1 757 AAWTHYGQFLFDRKRVTEAASMFAKAMVLA-----PED---FDIAFTAAGYLREIGKNQQAEDCYKKAAELQ 820 57778*************************.....775...669999999******************9987 PP == domain 6 score: 15.3 bits; conditional E-value: 4.4e-05 TPR_12 5 alnnlAavlrrlgrydeAlellekalel 32 a++nl+a+ + +g++deA++ + +al+l FUN_000537-T1 826 AHMNLGAMFHMQGKLDEAEKSYVRALQL 853 5568888888888888888888888876 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.1 0.00038 0.21 1 26 [. 540 565 .. 540 571 .. 0.91 2 ! 8.9 0.0 0.0045 2.6 1 28 [. 574 599 .. 574 606 .. 0.88 3 ! 9.9 0.0 0.0021 1.2 1 27 [. 608 634 .. 608 645 .. 0.87 4 ! 17.0 0.0 1.1e-05 0.0064 3 28 .. 655 680 .. 653 684 .. 0.86 5 ! 8.7 0.0 0.005 2.9 4 32 .. 693 719 .. 690 723 .. 0.83 6 ? 2.6 0.0 0.46 2.6e+02 11 35 .. 734 756 .. 726 757 .. 0.87 7 ? 0.6 0.0 2.1 1.2e+03 14 32 .. 771 789 .. 768 793 .. 0.80 8 ? 6.7 0.1 0.023 13 10 35 .. 801 824 .. 796 825 .. 0.84 9 ! 13.7 0.0 0.00013 0.075 1 32 [. 826 857 .. 826 861 .. 0.87 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00038 TPR_7 1 aLsaLariyrklGdydeAirlyerlL 26 aLs+L+++++++ + +eA++ y+++L FUN_000537-T1 540 ALSNLGNVLSSQKRKREAEDAYRKAL 565 89**********************55 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0045 TPR_7 1 aLsaLariyrklGdydeAirlyerlLal 28 ++++L+ ++ + ++ eA++ ye+ a+ FUN_000537-T1 574 THYNLGILLAEEKRFSEAVQSYEN--AI 599 579********************9..55 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0021 TPR_7 1 aLsaLariyrklGdydeAirlyerlLa 27 a+++L+ +++ +G +++A+++++ + + FUN_000537-T1 608 AHLNLGIVLSDMGHFEKALKVLRTAST 634 789*******************99655 PP == domain 4 score: 17.0 bits; conditional E-value: 1.1e-05 TPR_7 3 saLariyrklGdydeAirlyerlLal 28 ++L+ri+ +lG+++eAi++y + ++ FUN_000537-T1 655 YNLGRILAQLGKMEEAISVYLDAVET 680 69*******************95544 PP == domain 5 score: 8.7 bits; conditional E-value: 0.005 TPR_7 4 aLariyrklGdydeAirlyerlLalakdp 32 L+++y++ G eA+r+y++ +l+ +p FUN_000537-T1 693 MLGEAYSAAGYQNEAERCYKE--SLKSKP 719 79*******************..665554 PP == domain 6 score: 2.6 bits; conditional E-value: 0.46 TPR_7 11 klGdydeAirlyerlLalakdpedr 35 k+G+ eA++l+++ a + d +d+ FUN_000537-T1 734 KMGKIAEAEKLFKK--AQRLDANDP 756 488999********..****99998 PP == domain 7 score: 0.6 bits; conditional E-value: 2.1 TPR_7 14 dydeAirlyerlLalakdp 32 + eA++++ +++ la+++ FUN_000537-T1 771 RVTEAASMFAKAMVLAPED 789 678********88877766 PP == domain 8 score: 6.7 bits; conditional E-value: 0.023 TPR_7 10 rklGdydeAirlyerlLalakdpedr 35 r G+ ++A+++y++ a+ +p+++ FUN_000537-T1 801 REIGKNQQAEDCYKK--AAELQPQNP 824 459************..999999887 PP == domain 9 score: 13.7 bits; conditional E-value: 0.00013 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdp 32 a+ +L+ +++ +G+ deA++ y r+L+l++ + FUN_000537-T1 826 AHMNLGAMFHMQGKLDEAEKSYVRALQLKPGD 857 6789********************88877654 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.2 0.00011 0.064 8 46 .. 555 593 .. 548 593 .. 0.92 2 ! 24.5 0.0 6.1e-08 3.5e-05 1 51 [. 582 632 .. 582 635 .. 0.96 3 ? 7.2 0.0 0.016 9 27 56 .. 653 682 .. 651 690 .. 0.86 4 ! 27.1 0.2 9.7e-09 5.5e-06 8 63 .. 705 760 .. 700 765 .. 0.95 5 ! 18.9 1.4 3.5e-06 0.002 1 63 [. 766 828 .. 766 830 .. 0.96 6 ! 21.0 1.2 8e-07 0.00046 5 57 .. 804 856 .. 800 859 .. 0.90 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.00011 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAea 46 eA ++++al++ + a+ +++L+ +l + +r++eA + FUN_000537-T1 555 REAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQ 593 79***********************************75 PP == domain 2 score: 24.5 bits; conditional E-value: 6.1e-08 TPR_19 1 llaegdydeAlalLeqalaedPdnaearllLArallalgrldeAealLaal 51 l +e+++ eA++ +e+a+ P a+a+l+L+ +l +g++++A ++L ++ FUN_000537-T1 582 LAEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTA 632 679*********************************************986 PP == domain 3 score: 7.2 bits; conditional E-value: 0.016 TPR_19 27 arllLArallalgrldeAealLaalpaadp 56 ++++L+r+l +lg+++eA+ + ++ + p FUN_000537-T1 653 IKYNLGRILAQLGKMEEAISVYLDAVETRP 682 6899***************99988887776 PP == domain 4 score: 27.1 bits; conditional E-value: 9.7e-09 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpddpeyaa 63 +eA + +++ l+ Pd+ ++l++A+ l ++g+++eAe+l++++ + d++dp++++ FUN_000537-T1 705 NEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWT 760 589999*********************************************99985 PP == domain 5 score: 18.9 bits; conditional E-value: 3.5e-06 TPR_19 1 llaegdydeAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpddpeyaa 63 l++ ++ eA++++++a+ ++P++ +++ + A l + g+ +Ae +++ + +p++p++++ FUN_000537-T1 766 LFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLREIGKNQQAEDCYKKAAELQPQNPAAHM 828 678999*****************************************************9985 PP == domain 6 score: 21.0 bits; conditional E-value: 8e-07 TPR_19 5 gdydeAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpd 57 g+ ++A +++a ++ P+n++a+++L+ +g+ldeAe+ +++ +p FUN_000537-T1 804 GKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPG 856 8899*************************************988777777666 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.1 0.2 1.2e+02 5 29 .. 542 566 .. 538 572 .. 0.86 2 ? 6.8 0.1 0.034 20 3 42 .. 574 613 .. 572 615 .. 0.90 3 ? 5.9 0.0 0.065 37 2 27 .. 607 632 .. 606 637 .. 0.90 4 ! 11.4 0.0 0.0012 0.65 5 36 .. 655 686 .. 652 692 .. 0.88 5 ! 12.3 0.0 0.00057 0.33 6 43 .. 693 730 .. 688 730 .. 0.93 6 ! 23.4 0.1 1.5e-07 8.6e-05 3 43 .. 724 764 .. 722 765 .. 0.94 7 ! 13.3 0.1 0.00027 0.15 1 39 [. 756 794 .. 756 797 .. 0.93 8 ! 16.3 0.1 3e-05 0.017 5 43 .. 794 832 .. 790 833 .. 0.91 9 ! 11.8 0.0 0.00084 0.48 1 38 [. 824 861 .. 824 867 .. 0.87 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.2 TPR_14 5 lalarallalGdpdeAlellerala 29 l+++l +++ eA++++++al+ FUN_000537-T1 542 SNLGNVLSSQKRKREAEDAYRKALS 566 568999*****************96 PP == domain 2 score: 6.8 bits; conditional E-value: 0.034 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlala 42 ++ l+ +l++ ++++eA++ +e a+ P ++a+l+l+ FUN_000537-T1 574 THYNLGILLAEEKRFSEAVQSYENAIHFRPRLAAAHLNLG 613 5678999********************99**999999997 PP == domain 3 score: 5.9 bits; conditional E-value: 0.065 TPR_14 2 eawlalarallalGdpdeAlellera 27 +a+l l+ +l G++++Al++l+ a FUN_000537-T1 607 AAHLNLGIVLSDMGHFEKALKVLRTA 632 6889999****************976 PP == domain 4 score: 11.4 bits; conditional E-value: 0.0012 TPR_14 5 lalarallalGdpdeAlelleralaldPddpe 36 + l+r+l++lG+ +eA+ ++ +a+++ P + e FUN_000537-T1 655 YNLGRILAQLGKMEEAISVYLDAVETRPPHYE 686 6799*********************9997765 PP == domain 5 score: 12.3 bits; conditional E-value: 0.00057 TPR_14 6 alarallalGdpdeAlelleralaldPddpeawlalar 43 +l++a+ a+G eA++++++ l+ Pd+ ++l +a+ FUN_000537-T1 693 MLGEAYSAAGYQNEAERCYKESLKSKPDHLPVHLTYAK 730 799*****************************999986 PP == domain 6 score: 23.4 bits; conditional E-value: 1.5e-07 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlalar 43 ++l +a++l + G+ +eA++l+++a +ld +dp+aw +++ FUN_000537-T1 724 VHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQ 764 5789**********************************998 PP == domain 7 score: 13.3 bits; conditional E-value: 0.00027 TPR_14 1 peawlalarallalGdpdeAlelleralaldPddpeawl 39 p+aw ++++l+ +++ eA+ ++ +a l P+d ++ + FUN_000537-T1 756 PAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIAF 794 78********************************99876 PP == domain 8 score: 16.3 bits; conditional E-value: 3e-05 TPR_14 5 lalarallalGdpdeAlelleralaldPddpeawlalar 43 +a +l++ G+ ++A++++++a +l P++p+a+++l+ FUN_000537-T1 794 FTAAGYLREIGKNQQAEDCYKKAAELQPQNPAAHMNLGA 832 568999*****************************9986 PP == domain 9 score: 11.8 bits; conditional E-value: 0.00084 TPR_14 1 peawlalarallalGdpdeAlelleralaldPddpeaw 38 p+a++ l++ + +G++deA++ + ral+l P+d FUN_000537-T1 824 PAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPGDKLTE 861 678899999************************97665 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.21 1.2e+02 13 33 .. 538 558 .. 536 559 .. 0.88 2 ! 10.8 0.1 0.0013 0.72 1 34 [] 560 593 .. 560 593 .. 0.95 3 ! 14.1 0.0 0.00011 0.06 2 33 .. 595 626 .. 594 627 .. 0.96 4 ? 3.7 0.1 0.23 1.3e+02 17 33 .. 655 671 .. 655 672 .. 0.95 5 ? 0.5 0.0 2.5 1.4e+03 14 31 .. 689 706 .. 673 709 .. 0.70 6 ! 11.7 0.0 0.00062 0.35 1 33 [. 710 742 .. 710 743 .. 0.97 7 ? 7.2 0.0 0.017 9.9 1 32 [. 744 775 .. 744 776 .. 0.89 8 ? 5.0 0.0 0.086 49 2 33 .. 779 810 .. 778 811 .. 0.93 9 ! 25.1 0.1 3.2e-08 1.8e-05 1 33 [. 812 844 .. 812 845 .. 0.97 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.21 TPR_17 13 adayynLArlllnnGqleeAl 33 a+a+ nL+++l+ +++ eA+ FUN_000537-T1 538 AKALSNLGNVLSSQKRKREAE 558 789*********999999886 PP == domain 2 score: 10.8 bits; conditional E-value: 0.0013 TPR_17 1 lylkaleldPnnadayynLArlllnnGqleeAlq 34 +y+kal+ n ad +ynL++ll + +++ eA+q FUN_000537-T1 560 AYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQ 593 599*************************999987 PP == domain 3 score: 14.1 bits; conditional E-value: 0.00011 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 y+ a+ P a a+ nL+++l+ +G++e+Al FUN_000537-T1 595 YENAIHFRPRLAAAHLNLGIVLSDMGHFEKAL 626 999****************************8 PP == domain 4 score: 3.7 bits; conditional E-value: 0.23 TPR_17 17 ynLArlllnnGqleeAl 33 ynL+r+l ++G+ eeA+ FUN_000537-T1 655 YNLGRILAQLGKMEEAI 671 8*************997 PP == domain 5 score: 0.5 bits; conditional E-value: 2.5 TPR_17 14 dayynLArlllnnGqlee 31 ++++L+++++ G +e FUN_000537-T1 689 SLFNMLGEAYSAAGYQNE 706 578999999998885555 PP == domain 6 score: 11.7 bits; conditional E-value: 0.00062 TPR_17 1 lylkaleldPnnadayynLArlllnnGqleeAl 33 +y+++l+ P++ ++ +A +l ++G+ +eA+ FUN_000537-T1 710 CYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAE 742 8******************************98 PP == domain 7 score: 7.2 bits; conditional E-value: 0.017 TPR_17 1 lylkaleldPnnadayynLArlllnnGqleeA 32 l++ka +ld n++ a++ ++++l +++ eA FUN_000537-T1 744 LFKKAQRLDANDPAAWTHYGQFLFDRKRVTEA 775 6899999****************988887766 PP == domain 8 score: 5.0 bits; conditional E-value: 0.086 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 + ka+ l P ++d+ + A +l++ G+ ++A+ FUN_000537-T1 779 FAKAMVLAPEDFDIAFTAAGYLREIGKNQQAE 810 679999************************97 PP == domain 9 score: 25.1 bits; conditional E-value: 3.2e-08 TPR_17 1 lylkaleldPnnadayynLArlllnnGqleeAl 33 +y+ka el+P+n+ a+ nL+ +++G+l+eA+ FUN_000537-T1 812 CYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAE 844 8*******************************8 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.4 2.9e-07 0.00016 2 30 .. 538 566 .. 537 570 .. 0.93 2 ! 7.6 0.1 0.0098 5.5 7 32 .. 577 602 .. 572 606 .. 0.92 3 ! 7.8 0.0 0.0083 4.7 6 28 .. 610 632 .. 605 640 .. 0.86 4 ! 11.4 0.0 0.00061 0.35 6 32 .. 655 681 .. 651 681 .. 0.92 5 ! 11.5 0.1 0.00057 0.32 5 30 .. 691 716 .. 689 718 .. 0.93 6 ? 6.2 0.0 0.028 16 9 28 .. 729 748 .. 729 748 .. 0.92 7 ? 3.9 0.0 0.14 80 9 29 .. 763 783 .. 762 786 .. 0.91 8 ? 2.3 0.3 0.46 2.6e+02 9 31 .. 797 819 .. 796 820 .. 0.89 9 ! 11.9 0.0 0.00044 0.25 7 31 .. 829 853 .. 827 854 .. 0.95 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 2.9e-07 TPR_10 2 asslnnLanalraqgryeeAeelleeala 30 a +l+nL+n+l++q+r eAe+ +++al FUN_000537-T1 538 AKALSNLGNVLSSQKRKREAEDAYRKALS 566 679************************97 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0098 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+ +l + +r+ eA++ +e a+ r FUN_000537-T1 577 NLGILLAEEKRFSEAVQSYENAIHFR 602 9*********************9876 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0083 TPR_10 6 nnLanalraqgryeeAeelleea 28 nL+ +l+++g +e A++ l+ a FUN_000537-T1 610 LNLGIVLSDMGHFEKALKVLRTA 632 6****************999866 PP == domain 4 score: 11.4 bits; conditional E-value: 0.00061 TPR_10 6 nnLanalraqgryeeAeelleealair 32 nL+++l ++g+ eeA + +a+++r FUN_000537-T1 655 YNLGRILAQLGKMEEAISVYLDAVETR 681 5***********************987 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00057 TPR_10 5 lnnLanalraqgryeeAeelleeala 30 n L+ a++a g +eAe+ ++e+l+ FUN_000537-T1 691 FNMLGEAYSAAGYQNEAERCYKESLK 716 699********************996 PP == domain 6 score: 6.2 bits; conditional E-value: 0.028 TPR_10 9 analraqgryeeAeelleea 28 a +l ++g+ +eAe+l+++a FUN_000537-T1 729 AKYLNKMGKIAEAEKLFKKA 748 66899*************98 PP == domain 7 score: 3.9 bits; conditional E-value: 0.14 TPR_10 9 analraqgryeeAeelleeal 29 ++ l++++r +eA ++ +a+ FUN_000537-T1 763 GQFLFDRKRVTEAASMFAKAM 783 6789***************98 PP == domain 8 score: 2.3 bits; conditional E-value: 0.46 TPR_10 9 analraqgryeeAeelleealai 31 a +lr+ g+ + Ae+ +++a ++ FUN_000537-T1 797 AGYLREIGKNQQAEDCYKKAAEL 819 568999**************875 PP == domain 9 score: 11.9 bits; conditional E-value: 0.00044 TPR_10 7 nLanalraqgryeeAeelleealai 31 nL+++ qg+++eAe+ + +al++ FUN_000537-T1 829 NLGAMFHMQGKLDEAEKSYVRALQL 853 9*********************986 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.2 0.0055 3.1 56 141 .. 544 626 .. 536 635 .. 0.57 2 ! 17.1 0.0 9.1e-06 0.0052 56 156 .. 657 756 .. 655 757 .. 0.92 3 ! 33.5 0.4 8.1e-11 4.6e-08 47 152 .. 753 855 .. 750 861 .. 0.93 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0055 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAi 141 LG + s+++ ++A +A++kAl+ + n ++ ++ +L +e+ ++A + ++++++ p+ a l++ + g++e+A+ FUN_000537-T1 544 LGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILL---AEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKAL 626 666666677777777777777666666666655554333...34444555555555555555555555555555555555555554 PP == domain 2 score: 17.1 bits; conditional E-value: 9.1e-06 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAiaaWqkmlkll 151 LGri +l+++e+Ai+ + A++ +p + e + + + + +++Ae+ +k+ lk++p+ l + +A + g+++eA + ++k ++ l FUN_000537-T1 657 LGRILAQLGKMEEAISVYLDAVETRPPHYEPHSLFNMLGEAYSAAGYQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQR-L 751 9*****************************99999999999999999******************************************99765.6 PP TPR_CcmH_CycH 152 paddp 156 +a+dp FUN_000537-T1 752 DANDP 756 77776 PP == domain 3 score: 33.5 bits; conditional E-value: 8.1e-11 TPR_CcmH_CycH 47 pddatgWllLGriglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAia 142 +d +W+ +G+ + +++++A + f+kA+ lap++ +i+ + a L g ++++Ae+ +kk+ + +p+n a l+ + qg+++eA + FUN_000537-T1 753 ANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLREIG---KNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEK 845 6899******************************************997776...567************************************** PP TPR_CcmH_CycH 143 aWqkmlkllp 152 + + l+l p FUN_000537-T1 846 SYVRALQLKP 855 **99998765 PP >> TPR_Slam Surface lipoprotein assembly modifier, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.5 0.00025 0.14 56 100 .. 547 591 .. 541 593 .. 0.93 2 ! 15.2 0.0 5.3e-05 0.03 50 94 .. 575 619 .. 572 628 .. 0.89 3 ? 0.5 0.0 2 1.2e+03 48 78 .. 652 682 .. 644 691 .. 0.84 4 ! 11.5 0.1 0.00072 0.41 58 103 .. 699 744 .. 665 745 .. 0.84 5 ? 3.2 0.1 0.29 1.7e+02 54 103 .. 729 778 .. 727 779 .. 0.90 6 ! 14.8 0.1 7.2e-05 0.041 49 102 .. 792 845 .. 784 848 .. 0.92 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00025 TPR_Slam 56 larsqgnyaeAialYrellaekpdllpvrlqlAqaLfenkqneaA 100 ++ sq++ +eA ++Yr+ l+ ++++ ++l + L e+k+ ++A FUN_000537-T1 547 VLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEA 591 67899************************************9998 PP == domain 2 score: 15.2 bits; conditional E-value: 5.3e-05 TPR_Slam 50 kyaqAilarsqgnyaeAialYrellaekpdllpvrlqlAqaLfen 94 +y +il+ ++++++eA++ Y++ + +p l ++ l+l ++L + FUN_000537-T1 575 HYNLGILLAEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDM 619 78899**********************************999765 PP == domain 3 score: 0.5 bits; conditional E-value: 2 TPR_Slam 48 LlkyaqAilarsqgnyaeAialYrellaekp 78 +ky + ++ + g+++eAi+ Y ++++p FUN_000537-T1 652 SIKYNLGRILAQLGKMEEAISVYLDAVETRP 682 578999999999***********98888776 PP == domain 4 score: 11.5 bits; conditional E-value: 0.00072 TPR_Slam 58 rsqgnyaeAialYrellaekpdllpvrlqlAqaLfenkqneaAkdq 103 + g +eA + Y+e l+ kpd lpv l +A L + + +A++ FUN_000537-T1 699 SAAGYQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKL 744 3568889*************************99988888888765 PP == domain 5 score: 3.2 bits; conditional E-value: 0.29 TPR_Slam 54 AilarsqgnyaeAialYrellaekpdllpvrlqlAqaLfenkqneaAkdq 103 A +++ g++aeA +l+++ + + + ++ ++ q Lf+ k+ ++A+ FUN_000537-T1 729 AKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASM 778 5677889*********************************9999988865 PP == domain 6 score: 14.8 bits; conditional E-value: 7.2e-05 TPR_Slam 49 lkyaqAilarsqgnyaeAialYrellaekpdllpvrlqlAqaLfenkqneaAkd 102 +++ A +r+ g+ ++A + Y++ + +p++ ++ ++l ++ + ++A++ FUN_000537-T1 792 IAFTAAGYLREIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEK 845 678899999***********************************9999999986 PP >> HAT_PRP39_C PRP39 C-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.2 0.35 2e+02 71 129 .. 551 608 .. 545 616 .. 0.79 2 ! 30.3 0.4 9.4e-10 5.4e-07 5 131 .. 702 828 .. 698 835 .. 0.92 3 ! 20.7 0.1 8.4e-07 0.00048 20 125 .. 751 856 .. 749 872 .. 0.76 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.35 HAT_PRP39_C 71 skseeearnvyeractihlpkkpeirlawaafeEkqgnveeAreilealeeklpgllev 129 +k++ ea+++y++a+++ ++ ++ +++ + ++++++eA + +e+ + p l+ + FUN_000537-T1 551 QKRKREAEDAYRKALSY-RSNMADTHYNLGILLAEEKRFSEAVQSYENAIHFRPRLAAA 608 345789********875.6788899999999999999*****99999877666666655 PP == domain 2 score: 30.3 bits; conditional E-value: 9.4e-10 HAT_PRP39_C 5 tfEeeikrpYfhvkpleeaqlknWrkYldfeeeegdkerivvlyERcliacalyeefWlrYaryl.eskseeearnvyeractihlpkkpeirlaw 99 + +e +r Y + + + + l Y ++ + g+ ++++ l+ ++ a+ + W+ Y ++l ++k+++ea +++ +a+ + p+ +i +++ FUN_000537-T1 702 GYQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLfDRKRVTEAASMFAKAM-VLAPEDFDIAFTA 796 5889999*********************************************************9345679**********7.5789********* PP HAT_PRP39_C 100 aafeEkqgnveeAreilealeeklpgllevil 131 a + + g+ ++A++++++ e p++ +++ FUN_000537-T1 797 AGYLREIGKNQQAEDCYKKAAELQPQNPAAHM 828 *******************9999888776665 PP == domain 3 score: 20.7 bits; conditional E-value: 8.4e-07 HAT_PRP39_C 20 leeaqlknWrkYldfeeeegdkerivvlyERcliacalyeefWlrYaryles.kseeearnvyeractihlpkkpeirlawaafeEkqgnveeAre 114 l+ ++ ++W +Y +f ++ +++ ++ ++++ + ++ + a yl++ ++++a++ y++a+++ p++p+ +++ a+ +qg+++eA++ FUN_000537-T1 751 LDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLREiGKNQQAEDCYKKAAEL-QPQNPAAHMNLGAMFHMQGKLDEAEK 845 677777888888888888888888888888888888888888888888887735778888888888885.58888888888888888888888888 PP HAT_PRP39_C 115 ilealeeklpg 125 + + ++ pg FUN_000537-T1 846 SYVRALQLKPG 856 87776665554 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.5 0.27 1.5e+02 25 81 .. 540 597 .. 535 598 .. 0.84 2 ? 7.6 0.5 0.012 6.9 5 81 .. 554 631 .. 550 632 .. 0.89 3 ! 10.3 0.1 0.0017 0.98 5 80 .. 588 675 .. 584 677 .. 0.78 4 ! 18.5 0.5 4.7e-06 0.0027 6 80 .. 705 780 .. 701 782 .. 0.86 5 ! 16.2 0.3 2.4e-05 0.014 8 81 .. 741 815 .. 741 816 .. 0.92 6 ! 9.4 0.2 0.0033 1.9 8 79 .. 776 847 .. 773 850 .. 0.87 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.27 ANAPC3 25 dayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaLek 81 ++ l+++l ++++ ++A + rka ++++ + +y l+ l + k++ eA++ +e+ FUN_000537-T1 540 ALSNLGNVLSSQKRKREAEDAYRKAlSYRSNMADTHYNLGILLAEEKRFSEAVQSYEN 597 5566889999999999999999999888888889999999999999999999998886 PP == domain 2 score: 7.6 bits; conditional E-value: 0.012 ANAPC3 5 yknAiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaLek 81 ++A+ ++ ++l++ ++ ++ y l+ l +++++ +A++ ++a +++ +++ l+ +l +++++++Al++L+ FUN_000537-T1 554 KREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAiHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRT 631 57899999999*999999999999*********************8888888899999999999**********9975 PP == domain 3 score: 10.3 bits; conditional E-value: 0.0017 ANAPC3 5 yknAiflaerllaaepespedayl.lAqclflngqykrAyellrka.klneksl...........gcryllAqcllkLkkykeAldaLe 80 +++A+ +e ++ + + + +a+l l+ +l +g +++A+++lr+a + ++ l + y l++ l +L+k++eA++++ FUN_000537-T1 588 FSEAVQSYENAI-HFRPRLAAAHLnLGIVLSDMGHFEKALKVLRTAsTISGHGLkdpkhhahsiiSIKYNLGRILAQLGKMEEAISVYL 675 667777777788.6777777777767999999999999999999997777776666666677777888888899999999999999876 PP == domain 4 score: 18.5 bits; conditional E-value: 4.7e-06 ANAPC3 6 knAiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaLe 80 ++A+ ++ l+++p++ +++A++l ++g+ ++A +l++ka l+ ++++++ ++q l++ k++ eA +++ FUN_000537-T1 705 NEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAqRLDANDPAAWTHYGQFLFDRKRVTEAASMFA 780 566667777776666666667779***********************************************98876 PP == domain 5 score: 16.2 bits; conditional E-value: 2.4e-05 ANAPC3 8 AiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaLek 81 A+ l+ ++ ++++p + ++q lf +++ ++A + ka l++++ + ++ +A l +++k ++A+d+++k FUN_000537-T1 741 AEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAmVLAPEDFDIAFTAAGYLREIGKNQQAEDCYKK 815 566777777799999999999***************************************************987 PP == domain 6 score: 9.4 bits; conditional E-value: 0.0033 ANAPC3 8 AiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaL 79 A +a ++ pe+ + a++ A +l++ g+ ++A + +ka +l+++++++++ l+ + ++k++eA++ + FUN_000537-T1 776 ASMFAKAMV-LAPEDFDIAFTAAGYLREIGKNQQAEDCYKKAaELQPQNPAAHMNLGAMFHMQGKLDEAEKSY 847 444444555.99999999***************************************************9876 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 2.4e-05 0.014 3 58 .. 580 635 .. 578 650 .. 0.90 2 ? 2.4 0.0 0.41 2.3e+02 34 50 .. 656 672 .. 651 684 .. 0.86 3 ? 4.2 0.1 0.11 63 23 66 .. 750 793 .. 737 798 .. 0.91 4 ? 6.4 0.1 0.023 13 10 62 .. 805 857 .. 796 872 .. 0.86 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.4e-05 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeaylal 58 ++++e+++ +a + +e ++++P+ + + G+++ +g++e+Al+ L ++ + FUN_000537-T1 580 ILLAEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTASTI 635 67799*******************************************99987655 PP == domain 2 score: 2.4 bits; conditional E-value: 0.41 TPR_9 34 drGllyaqlgcleaAla 50 + G+++aqlg +e+A+ FUN_000537-T1 656 NLGRILAQLGKMEEAIS 672 689************85 PP == domain 3 score: 4.2 bits; conditional E-value: 0.11 TPR_9 23 llaPddpeerrdrGllyaqlgcleaAladLeaylalapdapdae 66 +l+ +dp + +G+ ++ + ++ +A+ +++++ lap++ d++ FUN_000537-T1 750 RLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIA 793 5899**********************************998876 PP == domain 4 score: 6.4 bits; conditional E-value: 0.023 TPR_9 10 dleralavverllllaPddpeerrdrGllyaqlgcleaAladLeaylalapda 62 ++++a ++ l+P+ p ++ G + + +g l +A + ++l+l+p + FUN_000537-T1 805 KNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPGD 857 5788999999999***********************************99944 PP >> TPR_5 Tetratrico peptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 0.00017 0.095 19 109 .. 590 686 .. 585 692 .. 0.79 2 ? 6.3 0.0 0.026 15 12 102 .. 699 784 .. 687 787 .. 0.78 3 ! 8.9 0.1 0.0042 2.4 3 74 .. 792 861 .. 791 873 .. 0.85 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00017 TPR_5 19 kavplYrraLaaGLagarrrqatiqLassLRnlGeleealaLLraeltrggdeldd.........alaaflaLvLadlgrereavailllalaehl 105 +av+ Y++a++ +r a + L L +G+ e+al++Lr t +g++l+d +++ l +La+lg+ +ea+++ l+a+ FUN_000537-T1 590 EAVQSYENAIHF---RPRLAAAHLNLGIVLSDMGHFEKALKVLRTASTISGHGLKDpkhhahsiiSIKYNLGRILAQLGKMEEAISVYLDAVETRP 682 677777777763...56777888999999******************999999988444433222234445669******************9988 PP TPR_5 106 prYr 109 p Y FUN_000537-T1 683 PHYE 686 8885 PP == domain 2 score: 6.3 bits; conditional E-value: 0.026 TPR_5 12 DsvGhedkavplYrraLaaGLagarrrqatiqLassLRnlGeleealaLLraeltrggdelddalaaflaLvLadlgrereavailllala 102 G +++a+ Y+++L+ ++ + + a L +G+++ea++L ++ + + d d a + L+d +r ea ++ +a++ FUN_000537-T1 699 SAAGYQNEAERCYKESLKS---KPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQ--RLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMV 784 4578889999999999875...34444566678999*************98765..5666678888999999************9999986 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0042 TPR_5 3 aaferagarDsvGhedkavplYrraLaaGLagarrrqatiqLassLRnlGeleeala.LLraeltrggdeldd 74 +af +ag +G++++a++ Y++a + +++ a + L + G+l+ea++ +ra++ ++gd+l++ FUN_000537-T1 792 IAFTAAGYLREIGKNQQAEDCYKKAAEL---QPQNPAAHMNLGAMFHMQGKLDEAEKsYVRALQLKPGDKLTE 861 79**********************9773...678889999999999999999999753788999999998875 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.24 1.4e+02 23 84 .. 537 599 .. 531 603 .. 0.78 2 ! 12.7 0.0 0.00024 0.13 10 85 .. 609 679 .. 606 690 .. 0.83 3 ! 11.9 0.1 0.00041 0.23 28 85 .. 692 750 .. 686 758 .. 0.81 4 ? 2.2 0.1 0.38 2.2e+02 6 48 .. 823 866 .. 821 879 .. 0.71 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.24 ARM_TT21 23 leeAlktLktAlklpg.kkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeai 84 +Al+ L + l+ ++ k+++++++++ s +s+ + +++l +l++ k+++eA + ++ai FUN_000537-T1 537 AAKALSNLGNVLSSQKrKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAI 599 567888888888887625556666777777888889999999999999999999998888886 PP == domain 2 score: 12.7 bits; conditional E-value: 0.00024 ARM_TT21 10 hlikakvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaie 85 hl + vl+ +g++e+Alk+L+tA +++g+ + +k+ + +s+ ++l ++l++l+k+eeA ++ +a+e FUN_000537-T1 609 HLNLGIVLSDMGHFEKALKVLRTASTISGHGLKD----PKHH-AHSIISIKYNLGRILAQLGKMEEAISVYLDAVE 679 67778999*******************8864333....3332.34568999****************999998876 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00041 ARM_TT21 28 ktLktAlklpgkkkskek.kkekessesdkvsvylelidvlsklkkveeAkkllqeaie 85 ++L +A++ +g +++ e+ +ke+ s+ d++ v+l++++ l+k++k++eA+kl+++a + FUN_000537-T1 692 NMLGEAYSAAGYQNEAERcYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQR 750 5788889988865554441566666788***************************9975 PP == domain 4 score: 2.2 bits; conditional E-value: 0.38 ARM_TT21 6 nplYhlikakvlkkegkleeAlktLktAlklp.gkkkskekkke 48 np h+ + + + +gkl+eA k+ Al+l g k ++e+ ++ FUN_000537-T1 823 NPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKpGDKLTEENLTK 866 66778888999999****************96355544444333 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.0073 4.1 1 25 [. 606 630 .. 606 631 .. 0.93 2 ? 2.5 0.0 0.77 4.4e+02 5 20 .. 655 670 .. 653 673 .. 0.90 3 ? 1.3 0.0 1.9 1.1e+03 6 23 .. 693 710 .. 692 713 .. 0.89 4 ? 7.8 0.0 0.015 8.3 1 21 [. 824 844 .. 824 844 .. 0.95 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0073 TPR_4 1 arallaLArallalGdldeAralle 25 a+a+l+L+ +l + G+++ A+ +l+ FUN_000537-T1 606 AAAHLNLGIVLSDMGHFEKALKVLR 630 68******************98887 PP == domain 2 score: 2.5 bits; conditional E-value: 0.77 TPR_4 5 laLArallalGdldeA 20 ++L+r l++lG +eA FUN_000537-T1 655 YNLGRILAQLGKMEEA 670 79*********98888 PP == domain 3 score: 1.3 bits; conditional E-value: 1.9 TPR_4 6 aLArallalGdldeAral 23 +L++a+ a+G eA++ FUN_000537-T1 693 MLGEAYSAAGYQNEAERC 710 69*********9999986 PP == domain 4 score: 7.8 bits; conditional E-value: 0.015 TPR_4 1 arallaLArallalGdldeAr 21 ++a+ +L+ + +G ldeA+ FUN_000537-T1 824 PAAHMNLGAMFHMQGKLDEAE 844 78******************7 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.2 1.4e-05 0.0079 38 182 .. 529 672 .. 522 680 .. 0.79 2 ! 13.5 0.0 7.8e-05 0.044 40 191 .. 606 752 .. 602 762 .. 0.80 3 ? 3.0 0.1 0.12 68 45 111 .. 693 753 .. 684 819 .. 0.64 4 ! 7.2 0.2 0.0065 3.7 82 115 .. 826 859 .. 804 867 .. 0.71 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 1.4e-05 TPR_MalT 38 artlatlvlGeasllqgdlesAlaalreaealarradslhv.tllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLl 132 r + + + a +g++ s+++ reae + r+a s+++ + + + ++ ll ++ ++ +A + y+ a++ ++ ++ l+ +l FUN_000537-T1 529 YRSGIPVNAAKALSNLGNVLSSQKRKREAEDAYRKALSYRSnMADTHYNLGILLAEEKRFSEAVQSYENAIHFRPRLAAAH--------LNLGIVL 616 55556666777778899**********************993455667999999*****************9976655443........3447789 PP TPR_MalT 133 yEwndLeeAeqhlqqgiqlgrql..ep....aaaleayvllarvalaqGeleeAet 182 ++++e+A + l+ + ++++++ +p + ++ ++ l r+ ++ G++eeA + FUN_000537-T1 617 SDMGHFEKALKVLRTASTISGHGlkDPkhhaHSIISIKYNLGRILAQLGKMEEAIS 672 99*****************9996565531114456688889999999999999965 PP == domain 2 score: 13.5 bits; conditional E-value: 7.8e-05 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaeal....a.rradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvglad 130 ++a+l+lG + g +e+Al++lr a+++ + + +++ h+ + + ++ +l + G++ +A+ y +a + + + +++ +l +l ++ FUN_000537-T1 606 AAAHLNLGIVLSDMGHFEKALKVLRTASTIsghgLkDPKHHAHSIISIKYNLGRILAQLGKMEEAISVYLDAVETRPPHYEPH-SLFNML----GE 696 68999***999999*************98743332133344455566667****************************99998.566666....99 PP TPR_MalT 131 LlyEwndLeeAeqhlqqgiqlgrqlepaaaleayvllarvalaqGeleeAetllqraerla 191 + + eAe++ +++++ + p ++ a+ G++ eAe+l+++a+rl FUN_000537-T1 697 AYSAAGYQNEAERCYKESLKSKPDHLP-----VHLTYAKYLNKMGKIAEAEKLFKKAQRLD 752 ******************887666655.....4455555566789999******9999985 PP == domain 3 score: 3.0 bits; conditional E-value: 0.12 TPR_MalT 45 vlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaq 111 +lGea+ ++g ++A+ ++e ++ ++ +h t a+ l + G+ ++A++++++a++l FUN_000537-T1 693 MLGEAYSAAGYQNEAERCYKESLKSKPDHLPVHLT------YAKYLNKMGKIAEAEKLFKKAQRLDA 753 55666666665555666665555554444444433......33444444777777777777777644 PP == domain 4 score: 7.2 bits; conditional E-value: 0.0065 TPR_MalT 82 allqqaellraqGqLhqAaetyqqalqlaqeskl 115 a + ++++ +qG+L +A++ y +alql + kl FUN_000537-T1 826 AHMNLGAMFHMQGKLDEAEKSYVRALQLKPGDKL 859 4466788888899999999999999998776555 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.5 0.027 15 56 139 .. 550 632 .. 532 686 .. 0.62 2 ! 18.9 3.1 2e-06 0.0012 146 273 .. 688 814 .. 655 817 .. 0.88 3 ! 19.6 3.6 1.2e-06 0.0007 151 276 .. 727 851 .. 724 854 .. 0.88 4 ? 5.0 0.1 0.035 20 142 184 .. 819 862 .. 814 867 .. 0.83 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.027 TPR_15 56 alqqeeeallAyrrlla.tgkaraedyerliallresrpkeaarlalaawqrfrsprfllsalellealkdwkqlasllasaeee 139 +++++ ea+ Ayr+ l + + y+ i l +e+r+ ea++ ++a +f +pr ++ l+l+ l d+ + ++ l+ + FUN_000537-T1 550 SQKRKREAEDAYRKALSyRSNMADTHYNLGILLAEEKRFSEAVQSYENAI-HF-RPRLAAAHLNLGIVLSDMGHFEKALKVLRTA 632 66777777777776554044445666666677777777777777666664.33.3666666666666666666666666665444 PP == domain 2 score: 18.9 bits; conditional E-value: 2e-06 TPR_15 146 eafwllraelerqegekkaAleayreAltlaPgdselragllWlLidlgrrdeLrkllkawkaraaaadasLweayAaAllllgqnrkALpyfrkk 241 + +++e+++++g +++A ++y+e l+ +P+ ++ ++ L+ +g+ +e kl k+ + a+d++ w y+ l ++ +A f k FUN_000537-T1 688 HSLFNMLGEAYSAAGYQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLD-ANDPAAWTHYGQFLFDRKRVTEAASMFAKA 782 44566789****************************************************99887.****************************** PP TPR_15 242 aaqnkddplwllaYADaLeqagradeAwrlRr 273 + +++d+ + ++ A L g++++A+ + FUN_000537-T1 783 MVLAPEDFDIAFTAAGYLREIGKNQQAEDCYK 814 *************************9987655 PP == domain 3 score: 19.6 bits; conditional E-value: 1.2e-06 TPR_15 151 lraelerqegekkaAleayreAltlaPgdselragllWlLidlgrrdeLrkllkawkaraaaadasLweayAaA..llllgqnrkALpyfrkkaaq 244 +a++ ++ g+ ++A + +++A +l+++d ++ + +L d++r e +++ ++ a ++ + a+ aA l +g+n++A ++k a+ FUN_000537-T1 727 TYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAM---VLAPEDFDIAFTAAgyLREIGKNQQAEDCYKKAAEL 819 6899*******************************************9777766555...4779999999977743446***************** PP TPR_15 245 nkddplwllaYADaLeqagradeAwrlRrqal 276 ++++p+ + + g+ deA++ +al FUN_000537-T1 820 QPQNPAAHMNLGAMFHMQGKLDEAEKSYVRAL 851 ***********999999***999998766666 PP == domain 4 score: 5.0 bits; conditional E-value: 0.035 TPR_15 142 lk.kseafwllraelerqegekkaAleayreAltlaPgdselra 184 l+ +++a + ++++ + +g+ ++A + y +Al+l+Pgd+ + FUN_000537-T1 819 LQpQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPGDKLTEE 862 5567778888888899999********************87665 PP >> FAT FAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.2 0.0045 2.5 251 308 .. 540 597 .. 511 627 .. 0.69 2 ! 13.2 0.1 9.8e-05 0.055 164 300 .. 622 773 .. 615 790 .. 0.69 3 ? 4.0 0.1 0.059 34 253 292 .. 801 833 .. 777 856 .. 0.83 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0045 FAT 251 wlaalqklnwseekseeilqaysaateldpswykawhtwalfnfevlskeeekkeeee 308 l++l++ +s+++++e++ ay++a ++++ ++++++++ + e ++ e ++ e+ FUN_000537-T1 540 ALSNLGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYEN 597 4455555555666688888888888888888888888887777776666655555544 PP == domain 2 score: 13.2 bits; conditional E-value: 9.8e-05 FAT 164 lslAekaLkklleedk...eewlp.pevvyaylkylwakgeqkealqkLrefvscllekke......................elssglevqeptn 233 ++ A k+L+ + + + + + ++ + + + g++ +l k++e +s +l+ e ++++ e + +++ FUN_000537-T1 622 FEKALKVLRTASTISGhglK---DpKHHAHSIISIKYNLGRILAQLGKMEEAISVYLDAVEtrpphyephslfnmlgeaysaaGYQNEAERCYKES 714 55555555555433332221...2223344444555566777888888888888888888777777766666555554444333333333337777 PP FAT 234 leeftkllarcylkkGewlaalqklnwseekseeilqaysaateldpswykawhtwalfnfevlske 300 l+ + + l ++l +++l++++k + e+++ +++a++ld + aw + ++f f +++ FUN_000537-T1 715 LKSKPDHL-PVHLTYAKYLNKMGK-------IAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVT 773 77777777.88999999*******.......*****************************9988765 PP == domain 3 score: 4.0 bits; conditional E-value: 0.059 FAT 253 aalqklnwseekseeilqaysaateldpswykawhtwalf 292 ++++k +++++ +y++a+el+p+ a+++++ + FUN_000537-T1 801 REIGK-------NQQAEDCYKKAAELQPQNPAAHMNLGAM 833 55555.......899*********************9865 PP >> NatA_aux_su N-terminal acetyltransferase A, auxiliary subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.1 0.0015 0.85 176 253 .. 550 633 .. 532 638 .. 0.76 2 ? -0.8 0.0 1.3 7.5e+02 37 71 .. 650 684 .. 639 692 .. 0.79 3 ! 15.3 0.3 1.8e-05 0.01 197 282 .. 693 778 .. 683 790 .. 0.85 4 ? 3.0 0.1 0.094 54 198 260 .. 796 858 .. 790 879 .. 0.81 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0015 NatA_aux_su 176 sesdnedsekepesallwtlyflAqhydk......lgsrekAleyidkaiehtptlvelymtKarilkhaGdlqkAaevmeear 253 s++++ ++e+ ++al + ++ hy+ ++ ++A++ ++ai+ p+l +++ + +l +G ++kA +v+ +a FUN_000537-T1 550 SQKRKREAEDAYRKALSYRSNMADTHYNLgillaeEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTAS 633 23333556677778888888888888887654322444559**************************************99886 PP == domain 2 score: -0.8 bits; conditional E-value: 1.3 NatA_aux_su 37 klavketkaelllkLgrkeeAeatyeaLlernpen 71 +++k +++l +Lg++eeA ++y + +e p + FUN_000537-T1 650 IISIKYNLGRILAQLGKMEEAISVYLDAVETRPPH 684 566777889999***********999888877765 PP == domain 3 score: 15.3 bits; conditional E-value: 1.8e-05 NatA_aux_su 197 flAqhydklgsrekAleyidkaiehtptlvelymtKarilkhaGdlqkAaevmeearkLDlaDRyiNskcakymLradevekAekt 282 +l y g +++A ++ + ++++p + +++t a+ l ++G + +A ++ ++a++LD +D ++ + + ++v +A+ + FUN_000537-T1 693 MLGEAYSAAGYQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASM 778 5677788889999*************************************************976666666666666666666555 PP == domain 4 score: 3.0 bits; conditional E-value: 0.094 NatA_aux_su 198 lAqhydklgsrekAleyidkaiehtptlvelymtKarilkhaGdlqkAaevmeearkLDlaDR 260 A + ++g+ ++A ++ ka e +p+ +m+ + ++ +G l++A + +a +L D+ FUN_000537-T1 796 AAGYLREIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKPGDK 858 566777889999999999999999999999999999999999999999999888888776665 PP >> DUF7017 Domain of unknown function (DUF7017) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.43 2.5e+02 50 101 .. 554 602 .. 540 607 .. 0.77 2 ? 5.9 0.0 0.029 17 4 30 .. 654 680 .. 652 721 .. 0.77 3 ! 16.2 1.1 2e-05 0.011 5 103 .. 726 822 .. 724 824 .. 0.85 4 ? 3.6 0.1 0.16 89 7 72 .. 796 862 .. 791 877 .. 0.64 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.43 DUF7017 50 eelalaclckaLlcksdeeflvkvreklaelLiekgeyaeAkaeiekvieir 101 ++ a +++ kaL+ +s+ + +l lL+e+++++eA e++i +r FUN_000537-T1 554 KREAEDAYRKALSYRSNMA---DTHYNLGILLAEEKRFSEAVQSYENAIHFR 602 3346788999999988765...9999999************99999998877 PP == domain 2 score: 5.9 bits; conditional E-value: 0.029 DUF7017 4 kYykaklLlklgreeealelllpfakk 30 kY+ +++L +lg++eea +++l + + FUN_000537-T1 654 KYNLGRILAQLGKMEEAISVYLDAVET 680 8********************988876 PP == domain 3 score: 16.2 bits; conditional E-value: 2e-05 DUF7017 5 YykaklLlklgreeealelllpfakkkrnefWvWellAelyeddde.elalaclckaLlcksdeeflvkvreklaelLiekgeyaeAkaeiekvie 99 + +ak L k+g+ +ea +l+ + + + n+ +W +++++ d ++ + a ++++ka+ ++ ++ + a +L e g+ ++A + +k+ e FUN_000537-T1 726 LTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRvTEAASMFAKAMVLAPEDF---DIAFTAAGYLREIGKNQQAEDCYKKAAE 818 679************************************988877724467899***99988775...7778889999999999999888888877 PP DUF7017 100 iree 103 ++ + FUN_000537-T1 819 LQPQ 822 7655 PP == domain 4 score: 3.6 bits; conditional E-value: 0.16 DUF7017 7 kaklLlklgreeealelllpfakkkrnefWvWellAelyedd.deelalaclckaLlcksdeeflvk 72 a L+++g++++a + + + a + ++ + +l+++++ + + + a + + +aL++k ++ + + FUN_000537-T1 796 AAGYLREIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQgKLDEAEKSYVRALQLKPGDKLTEE 862 5666777777777777777777777777777777776655431445566777777777766665554 PP >> Suf Suppressor of forked protein (Suf) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.32 1.8e+02 464 520 .. 547 606 .. 536 613 .. 0.69 2 ? 2.9 0.1 0.078 44 296 340 .. 704 748 .. 674 754 .. 0.82 3 ! 17.0 0.1 4.1e-06 0.0023 280 344 .. 756 819 .. 753 879 .. 0.81 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.32 Suf 464 vvekleeekeklkeiykkfieyeskfgdls....svlklekrlaeafpeekeielfvdRyk 520 v+++++ ++ ++++ y+k ++y s++ d + +l+ ekr++ea+++ ++ +f R FUN_000537-T1 547 VLSSQKRKR-EAEDAYRKALSYRSNMADTHynlgILLAEEKRFSEAVQSYENAIHFRPRLA 606 455555555.599999999999999987541111456668899999888777666766655 PP == domain 2 score: 2.9 bits; conditional E-value: 0.078 Suf 296 eeeaaklleraikalpesllLtfklaeleEsrnkiekvkeiyekl 340 ++ea++++++++k p+ l +++ +a + + ki +++++++k FUN_000537-T1 704 QNEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKA 748 478888999999999999999999999999999999999998875 PP == domain 3 score: 17.0 bits; conditional E-value: 4.1e-06 Suf 280 peiWyeaaeyleesskeeeaaklleraikalpesllLtfklaeleEsrnkiekvkeiyeklldal 344 p W ++ ++l++ ++++eaa+++ +a+ + pe + ++f a + + k ++++++y+k +l FUN_000537-T1 756 PAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLREIGKNQQAEDCYKKAA-EL 819 66799999999999999999999999999999999999999999999999999999999876.33 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.1 0.18 1e+02 2 28 .. 540 566 .. 539 570 .. 0.89 2 ? 4.9 0.0 0.13 71 3 27 .. 575 599 .. 573 603 .. 0.89 3 ? 3.0 0.0 0.48 2.7e+02 2 24 .. 608 630 .. 607 632 .. 0.92 4 ? 7.8 0.0 0.015 8.3 4 28 .. 655 679 .. 654 683 .. 0.88 5 ? -0.7 0.1 7.8 4.4e+03 5 29 .. 693 717 .. 693 721 .. 0.80 6 ? 1.8 0.3 1.2 6.7e+02 7 27 .. 729 749 .. 725 754 .. 0.81 7 ? -0.7 0.0 7.8 4.4e+03 5 26 .. 761 782 .. 757 788 .. 0.77 8 ? 2.0 0.2 1.1 6e+02 10 32 .. 800 822 .. 794 823 .. 0.83 9 ? 1.5 0.1 1.5 8.3e+02 2 25 .. 826 849 .. 825 855 .. 0.82 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.18 TPR_6 2 AllklalsylelgdkdeAkaalqrlik 28 Al +l+ + +++k eA +a+++ ++ FUN_000537-T1 540 ALSNLGNVLSSQKRKREAEDAYRKALS 566 777999*****************9876 PP == domain 2 score: 4.9 bits; conditional E-value: 0.13 TPR_6 3 llklalsylelgdkdeAkaalqrli 27 ++l+ ++ e +++ eA++ ++ i FUN_000537-T1 575 HYNLGILLAEEKRFSEAVQSYENAI 599 699*******99*********9876 PP == domain 3 score: 3.0 bits; conditional E-value: 0.48 TPR_6 2 AllklalsylelgdkdeAkaalq 24 A l+l+ + +g +++A+++l+ FUN_000537-T1 608 AHLNLGIVLSDMGHFEKALKVLR 630 7899****************997 PP == domain 4 score: 7.8 bits; conditional E-value: 0.015 TPR_6 4 lklalsylelgdkdeAkaalqrlik 28 ++l++++ +lg+++eA++++ ++ FUN_000537-T1 655 YNLGRILAQLGKMEEAISVYLDAVE 679 89****************9987776 PP == domain 5 score: -0.7 bits; conditional E-value: 7.8 TPR_6 5 klalsylelgdkdeAkaalqrlikk 29 +l+++y ++g ++eA + +++ +k+ FUN_000537-T1 693 MLGEAYSAAGYQNEAERCYKESLKS 717 599*****99888999999887776 PP == domain 6 score: 1.8 bits; conditional E-value: 1.2 TPR_6 7 alsylelgdkdeAkaalqrli 27 a+ + ++g+ +eA +++++ FUN_000537-T1 729 AKYLNKMGKIAEAEKLFKKAQ 749 565677***********9975 PP == domain 7 score: -0.7 bits; conditional E-value: 7.8 TPR_6 5 klalsylelgdkdeAkaalqrl 26 ++++ ++ ++ +eA++++++ FUN_000537-T1 761 HYGQFLFDRKRVTEAASMFAKA 782 5677788889********9986 PP == domain 8 score: 2.0 bits; conditional E-value: 1.1 TPR_6 10 ylelgdkdeAkaalqrlikkYPd 32 ++e g+ ++A + +++ + P+ FUN_000537-T1 800 LREIGKNQQAEDCYKKAAELQPQ 822 45699***********9998886 PP == domain 9 score: 1.5 bits; conditional E-value: 1.5 TPR_6 2 AllklalsylelgdkdeAkaalqr 25 A ++l+ + ++g+ deA + + r FUN_000537-T1 826 AHMNLGAMFHMQGKLDEAEKSYVR 849 66789999999*******998855 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.1 5.1e-05 0.029 101 158 .. 544 601 .. 522 618 .. 0.89 2 ! 7.8 0.2 0.0066 3.8 99 159 .. 726 786 .. 711 801 .. 0.88 3 ? 2.6 0.2 0.26 1.5e+02 108 159 .. 803 854 .. 795 860 .. 0.89 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 5.1e-05 ARM_TT21_C 101 ladiyiqsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWkl 158 l ++ +++++ +Ae+ +k+l+y ++ a lG++ +e+++++A+++Ye+A ++ FUN_000537-T1 544 LGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAIHF 601 6777778899999******************************************876 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0066 ARM_TT21_C 99 LlladiyiqsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWkls 159 L a+ ++gk+ +Ae+L kk+ + + + A+ +G +++ ++Aa++++kA l+ FUN_000537-T1 726 LTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLA 786 6677777899**********************************************98776 PP == domain 3 score: 2.6 bits; conditional E-value: 0.26 ARM_TT21_C 108 sgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWkls 159 gk ++Ae+ kk+ + A lG++ + + +A ++Y +A +l+ FUN_000537-T1 803 IGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLK 854 589999***************************************9999886 PP >> T7SS_EccA1_N T7SS, ESX-1 secretion system protein EccA1, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.1 0.00041 0.23 108 195 .. 547 633 .. 522 640 .. 0.85 2 ? 2.7 0.0 0.15 86 171 237 .. 654 720 .. 641 724 .. 0.82 3 ? 2.3 0.0 0.21 1.2e+02 100 137 .. 723 760 .. 719 771 .. 0.82 4 ? 4.6 0.5 0.042 24 203 241 .. 788 826 .. 757 834 .. 0.70 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00041 T7SS_EccA1_N 108 sliaagdyaeAeevldeapk.agdeeivayvravlhfrtqrWpDVlaalarsaewedeylaaaakvmvGtAlaqLGlFeeAlrrleeae 195 l ++++ +eAe++ +a + + +y ++l + +r ++ ++ +++ + + ++ aaa++ +G+ l +G Fe+Al+ l++a FUN_000537-T1 547 VLSSQKRKREAEDAYRKALSyRSNMADTHYNLGILLAEEKRFSEAVQSYENAIHFRPRL--AAAHLNLGIVLSDMGHFEKALKVLRTAS 633 46778999999999998765245566778********************9999999886..799*******************999875 PP == domain 2 score: 2.7 bits; conditional E-value: 0.15 T7SS_EccA1_N 171 kvmvGtAlaqLGlFeeAlrrleeaedgpipaaaaeaaaftlgLalReqgdeeeAravleelyardpe 237 k+ +G laqLG eeA++ +a ++ p+ +++ +lg a+ + g ++eA+++ +e ++p+ FUN_000537-T1 654 KYNLGRILAQLGKMEEAISVYLDAVETRPPHYEPHSLFNMLGEAYSAAGYQNEAERCYKESLKSKPD 720 56688899***********777777777777777777777899999999999999999998888886 PP == domain 3 score: 2.3 bits; conditional E-value: 0.21 T7SS_EccA1_N 100 eialAyAasliaagdyaeAeevldeapkagdeeivayv 137 ++l yA l + g++aeAe++ ++a++ ++ +a++ FUN_000537-T1 723 PVHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWT 760 6789999999999******9999999887777777776 PP == domain 4 score: 4.6 bits; conditional E-value: 0.042 T7SS_EccA1_N 203 aaeaaaftlgLalReqgdeeeAravleelyardpefeaa 241 + ++aft + lRe g++++A+++ +++ +p++ aa FUN_000537-T1 788 EDFDIAFTAAGYLREIGKNQQAEDCYKKAAELQPQNPAA 826 35577899999*******************999987654 PP >> TPR_21 Tetratricopeptide repeat-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.1 0.022 12 153 175 .. 545 567 .. 536 578 .. 0.86 2 ? 5.2 0.1 0.04 23 113 173 .. 606 678 .. 580 680 .. 0.62 3 ! 8.4 0.0 0.0041 2.3 116 179 .. 654 721 .. 640 737 .. 0.77 4 ? -0.7 0.4 2.6 1.5e+03 147 147 .. 793 793 .. 724 834 .. 0.53 5 ? 5.2 0.3 0.038 22 153 181 .. 831 862 .. 805 871 .. 0.81 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.022 TPR_21 153 GDilvaqgkldeAraAYqaAlaa 175 G +l +q ++ eA +AY++Al+ FUN_000537-T1 545 GNVLSSQKRKREAEDAYRKALSY 567 99******************975 PP == domain 2 score: 5.2 bits; conditional E-value: 0.04 TPR_21 113 avarlrLarvllaekkydeALktL.........eakkdeafaalvaelk...GDilvaqgkldeAraAYqaAl 173 a a+l L vl + +++++ALk+L k+++ a ++ +k G il++ gk++eA + Y +A+ FUN_000537-T1 606 AAAHLNLGIVLSDMGHFEKALKVLrtastisghGLKDPKHHAHSIISIKynlGRILAQLGKMEEAISVYLDAV 678 568999999*************995444443331223333444444444444777777777777777777776 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0041 TPR_21 116 rlrLarvllaekkydeALkt.L..eakkdeafaal.vaelkGDilvaqgkldeAraAYqaAlaaleee 179 + L r+l++ +k++eA+++ L ++ + ++ + ++ G+++ a g ++eA Y+++l++ + FUN_000537-T1 654 KYNLGRILAQLGKMEEAISVyLdaVETRPPHYEPHsLFNMLGEAYSAAGYQNEAERCYKESLKSKPDH 721 45699************986343333456678765156999********************9987655 PP == domain 4 score: -0.7 bits; conditional E-value: 2.6 TPR_21 147 l 147 + FUN_000537-T1 793 A 793 1 PP == domain 5 score: 5.2 bits; conditional E-value: 0.038 TPR_21 153 GDilvaqgkldeAraAYqaAlaaleeee...r 181 G ++ qgkldeA + Y +Al+ ++ + FUN_000537-T1 831 GAMFHMQGKLDEAEKSYVRALQLKPGDKlteE 862 778999***************98777755433 PP >> HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.1 1.2e+03 69 122 .. 547 600 .. 537 606 .. 0.79 2 ! 17.6 0.1 6.1e-06 0.0035 68 125 .. 730 787 .. 705 822 .. 0.74 3 ? -0.7 0.0 2.7 1.6e+03 77 125 .. 807 855 .. 795 858 .. 0.84 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.1 HAT_Syf1_CNRKL1_N 69 pvkkeeeyekvnnlferalvllnkmpriWldYlefllkqkkvtktrrtfdraLr 122 +++++++ +++++++ +al + ++m ++ +l ++k+ +++ + +++a++ FUN_000537-T1 547 VLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAIH 600 556677888899999999999999999888888888888888888888888776 PP == domain 2 score: 17.6 bits; conditional E-value: 6.1e-06 HAT_Syf1_CNRKL1_N 68 npvkkeeeyekvnnlferalvllnkmpriWldYlefllkqkkvtktrrtfdraLralp 125 ++++k +++++++lf++a l + p W++Y +fl ++k+vt++ +f +a+ p FUN_000537-T1 730 KYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLAP 787 445566788999*****************************************98777 PP == domain 3 score: -0.7 bits; conditional E-value: 2.7 HAT_Syf1_CNRKL1_N 77 ekvnnlferalvllnkmpriWldYlefllkqkkvtktrrtfdraLralp 125 +++++++++a l + p ++ + q k+ ++ + + raL+ p FUN_000537-T1 807 QQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQLKP 855 6788899999999999999999999999999999999999999998665 PP >> HAT_Syf1_CNRKL1_C Pre-mRNA-splicing factor Syf1/CRNKL1 C-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 0.027 15 115 161 .. 554 600 .. 535 607 .. 0.88 2 ? 1.5 0.0 0.25 1.4e+02 177 238 .. 658 718 .. 604 722 .. 0.68 3 ! 8.8 0.3 0.0014 0.81 11 75 .. 724 784 .. 716 796 .. 0.83 4 ? 1.3 0.0 0.27 1.5e+02 111 162 .. 802 853 .. 794 855 .. 0.92 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.027 HAT_Syf1_CNRKL1_C 115 lestkavYdrileLriatpqiivnyaalleenkyfeesfkvyergve 161 +++ +Y + l r +++ n ll e+k f e+ + ye +++ FUN_000537-T1 554 KREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAIH 600 4577889************************************9986 PP == domain 2 score: 1.5 bits; conditional E-value: 0.25 HAT_Syf1_CNRKL1_C 177 skfvkRkggskleraRdlfeqalekaPake.akklyllyakleeeyGlarramkiyeratkav 238 ++++ g k+e a ++ +a+e+ P++ ++l+ + ++ G + +a + y+++ k FUN_000537-T1 658 GRILAQLG--KMEEAISVYLDAVETRPPHYePHSLFNMLGEAYSAAGYQNEAERCYKESLKSK 718 34443333..69************999875168999999999999999999999999887765 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0014 HAT_Syf1_CNRKL1_C 11 lwvefakfyeekgdlenarkifekavkveykkvdelaevwcewaelelrkenfdealevlkrata 75 +++++ak+ ++ g++++a+k+f+ka + + + + + w+++ ++ + ++++ ea ++ ++a+ FUN_000537-T1 724 VHLTYAKYLNKMGKIAEAEKLFKKAQRLDAN---D-PAAWTHYGQFLFDRKRVTEAASMFAKAMV 784 5789*********************998744...3.34699999999999999999999988865 PP == domain 4 score: 1.3 bits; conditional E-value: 0.27 HAT_Syf1_CNRKL1_C 111 slgtlestkavYdrileLriatpqiivnyaalleenkyfeesfkvyergvel 162 +g+ ++++ Y + eL+ +p +n a+ + +e+ k y r+++l FUN_000537-T1 802 EIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRALQL 853 588999999*************************************999886 PP >> ARM_TT21_5th TT21 fifth ARM repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.1 1.5 8.4e+02 37 98 .. 540 598 .. 535 612 .. 0.78 2 ? 1.6 0.0 0.8 4.5e+02 14 76 .. 585 647 .. 571 671 .. 0.81 3 ! 9.2 0.0 0.0036 2.1 18 65 .. 705 752 .. 693 764 .. 0.88 4 ? 6.2 0.1 0.031 18 11 90 .. 766 842 .. 762 852 .. 0.79 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 1.5 ARM_TT21_5th 37 aLarliellrrsGkleeaekflekaekassraklepgfnyckglyewytgklneaLrefnka 98 aL++l ++l ++ + +eae +++ka + ++ ++ +y g++ ++ +ea++++++a FUN_000537-T1 540 ALSNLGNVLSSQKRKREAEDAYRKALSY---RSNMADTHYNLGILLAEEKRFSEAVQSYENA 598 6777777777777777777777666554...4567788999999999999999999999877 PP == domain 2 score: 1.6 bits; conditional E-value: 0.8 ARM_TT21_5th 14 kqdlekAifhfqqlLekkpdnyeaLarliellrrsGkleeaekflekaekassraklepgfny 76 + + +A++ +++ ++ +p +a +l +l +G+ e+a k+l++a++ s + ++p + FUN_000537-T1 585 EKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTASTISGHGLKDPKHHA 647 567889999999999999999999999999999999999999999999998888777777665 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0036 ARM_TT21_5th 18 ekAifhfqqlLekkpdnyeaLarliellrrsGkleeaekflekaekas 65 ++A + +++ L++kpd+ + + l ++Gk++eaek+++ka++ FUN_000537-T1 705 NEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLD 752 57889999************************************9854 PP == domain 4 score: 6.2 bits; conditional E-value: 0.031 ARM_TT21_5th 11 afrkqdlekAifhfqqlLekkpdnyeaLarliellrrsGkleeaekflekaekassraklepgfnyckglyewytgklne 90 +f ++ +++A++ f + + p+++++ lr Gk ++ae +++ka++ + + +p + g + +++gkl e FUN_000537-T1 766 LFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLREIGKNQQAEDCYKKAAELQPQ---NPAAHMNLGAMFHMQGKLDE 842 6889999999*************************************9999886544...45555555555555555555 PP >> ARM_TT21_2nd Tetratricopeptide repeat protein 21 second ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.9 5.1e+02 159 199 .. 25 65 .. 24 72 .. 0.79 2 ? 1.7 0.1 0.36 2e+02 47 113 .. 562 629 .. 549 686 .. 0.63 3 ? 3.9 0.1 0.08 45 55 92 .. 718 758 .. 703 763 .. 0.72 4 ! 8.8 0.1 0.0024 1.4 40 111 .. 773 845 .. 764 848 .. 0.81 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.9 ARM_TT21_2nd 159 hfsklqglpfGieYlekLnpdfLleivkeylefaplqPtka 199 h++++ +l+ + Y+++L df+++ ++ +l+ + l P+++ FUN_000537-T1 25 HTAAVSSLAGLLCYFNSLSADFVYDDSRAILKNSDLLPATP 65 6667777777788************9999998877777655 PP == domain 2 score: 1.7 bits; conditional E-value: 0.36 ARM_TT21_2nd 47 eralslsrnaeylaeelrillll.gkvkeaekiykealeldeessvallggiicqllegqledAeqQL 113 +als +n ++ +l+ill + +++ ea + y++a+ + +a l + i g++e+A + L FUN_000537-T1 562 RKALSYRSNMADTHYNLGILLAEeKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVL 629 67888889999999999999998456999999999999887554444443333333345666665555 PP == domain 3 score: 3.9 bits; conditional E-value: 0.08 ARM_TT21_2nd 55 naeylaeel...rillllgkvkeaekiykealeldeessva 92 ++++l l ++l ++gk+ eaek++k+a +ld ++++a FUN_000537-T1 718 KPDHLPVHLtyaKYLNKMGKIAEAEKLFKKAQRLDANDPAA 758 555555554111455556899**************888776 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0024 ARM_TT21_2nd 40 qelrklleralslsrnaeyla.eelrillllgkvkeaekiykealeldeessvallggiicqllegqledAeq 111 +e+ ++ ++a+ l++++ ++a + +++l gk ++ae yk+a+el+ ++++a + + + ++g+l++Ae+ FUN_000537-T1 773 TEAASMFAKAMVLAPEDFDIAfTAAGYLREIGKNQQAEDCYKKAAELQPQNPAAHMNLGAMFHMQGKLDEAEK 845 5667788888899976655551566788788*****************99999888888999*********96 PP >> ARM_TT21_N Tetratricopeptide repeat protein 21 N-terminal ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.089 51 79 211 .. 589 731 .. 582 737 .. 0.63 2 ! 10.7 0.5 0.00078 0.44 82 189 .. 738 845 .. 735 856 .. 0.84 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.089 ARM_TT21_N 79 reavaeleaklkeeekkkaaeeaslylaalfllllgkydkAreyidra.......lklsssssae....alilkGWieltsgkeqkkaqelfeeag 163 eav+++e+ ++ + + + a+++ +++l +g+++kA +++ a lk ++++a + G i ++gk ++++ ++++++ FUN_000537-T1 589 SEAVQSYENAIHFRPRLA----AAHLNLGIVLSDMGHFEKALKVLRTAstisghgLKD-PKHHAHsiisIKYNLGRILAQLGKMEEAISVYLDAVE 679 689999999999766553....334567999999999999999998884444433332.2222221111333346666777888888888888875 PP ARM_TT21_N 164 eq......knpdallGkakylekrknysealevlnqlivaypkflpaliekmkl 211 ++ +++ +lG+a +n ea + ++ + + p++lp + +k FUN_000537-T1 680 TRpphyepHSLFNMLGEAYSAAGYQN--EAERCYKESLKSKPDHLPVHLTYAKY 731 53222111445567777777766666..78888888888888888888877776 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00078 ARM_TT21_N 82 vaeleaklkeeekkkaaeeaslylaalfllllgkydkAreyidralklsssssaealilkGWieltsgkeqkkaqelfeea.geqknpdallGkak 176 +ae e+ k++++ +a++ a+ + + fl+ +++ +A ++ +a+ l+++++ a + G++ + gk+q+++ + ++a ++ +np a + FUN_000537-T1 738 IAEAEKLFKKAQRLDANDPAAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLR-EIGKNQQAEDCYKKAAeLQPQNPAAHMNLGA 832 7888888899888888888888899************************999999999999986.7788887766565555345699********* PP ARM_TT21_N 177 ylekrknyseale 189 ++ ++++++ea + FUN_000537-T1 833 MFHMQGKLDEAEK 845 *******999975 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 1.3 7.3e+02 141 174 .. 538 571 .. 533 580 .. 0.70 2 ! 11.3 0.2 0.00041 0.23 93 172 .. 600 682 .. 581 718 .. 0.81 3 ? 0.6 0.2 0.77 4.4e+02 146 169 .. 727 750 .. 688 764 .. 0.66 4 ? 5.8 3.1 0.02 11 100 232 .. 757 873 .. 724 877 .. 0.72 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.3 TPR_NPHP3 141 arslhqLagLyaqwgkfstaealykqaleiyena 174 a++l +L ++ + ++ + ae+ y++al+ n+ FUN_000537-T1 538 AKALSNLGNVLSSQKRKREAEDAYRKALSYRSNM 571 6677777777777777788888888888765554 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00041 TPR_NPHP3 93 ltlakvadlyealGrflkdlgllsqalpaLqraLeiRetal.dPDhP..lvarslhqLagLyaqwgkfstaealykqaleiye 172 + ++a + lG l d+g ++al+ L+ a i l dP h ++ + +++L ++ aq gk + a ++y +a+e FUN_000537-T1 600 HFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTASTISGHGLkDPKHHahSIISIKYNLGRILAQLGKMEEAISVYLDAVETRP 682 335678999999************************98877699985335778899**********************99765 PP == domain 3 score: 0.6 bits; conditional E-value: 0.77 TPR_NPHP3 146 qLagLyaqwgkfstaealykqale 169 + a+ ++ gk + ae+l+k+a FUN_000537-T1 727 TYAKYLNKMGKIAEAEKLFKKAQR 750 345666677777777777777754 PP == domain 4 score: 5.8 bits; conditional E-value: 0.02 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqk 195 + G+fl d ++ a++ +a+ +l P++ +a + ag + gk ++ae+ yk+a e+ + + h+ l ++++ FUN_000537-T1 757 AAWTHYGQFLFDRKRVTEAASMFAKAM-----VLAPEDFDIAFT---AAGYLREIGKNQQAEDCYKKAAELQPQN-PAAHM-------NLGAMFHM 836 357778888888888888888888886.....677888777755...5788888999999999999999876443.34444.......46778999 PP TPR_NPHP3 196 qdkhdlaeplkkravairkkakkskaklaevdvlrrr 232 q k+d ae ra++++ k ++++l++ +lrr+ FUN_000537-T1 837 QGKLDEAEKSYVRALQLKPGDKLTEENLTKLRSLRRK 873 ******************9999999999999999998 PP >> TPPII_C Tripeptidyl peptidase II, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.00057 0.32 32 61 .. 705 734 .. 703 750 .. 0.91 2 ? 0.3 0.0 2.8 1.6e+03 32 55 .. 807 830 .. 798 836 .. 0.88 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00057 TPPII_C 32 ekaeklYeellaafPdhlqvhlamlqnlds 61 ++ae+ Y+e l+ Pdhl+vhl + + l++ FUN_000537-T1 705 NEAERCYKESLKSKPDHLPVHLTYAKYLNK 734 589*******************99988865 PP == domain 2 score: 0.3 bits; conditional E-value: 2.8 TPPII_C 32 ekaeklYeellaafPdhlqvhlam 55 ++ae Y++ ++ P++ ++h+++ FUN_000537-T1 807 QQAEDCYKKAAELQPQNPAAHMNL 830 689******************986 PP >> TPR_20 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.37 2.1e+02 6 45 .. 590 629 .. 585 632 .. 0.90 2 ? -0.9 0.0 5.3 3e+03 24 50 .. 653 679 .. 644 683 .. 0.87 3 ? 4.1 0.0 0.15 83 12 46 .. 712 745 .. 702 764 .. 0.83 4 ? 4.6 0.6 0.1 59 12 49 .. 814 851 .. 805 860 .. 0.83 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.37 TPR_20 6 pelaaleaalaadpddlearldlAlallaagrneeAleqL 45 + +++ e+a+ +p +a+l+l+ +l g+ e+Al+ L FUN_000537-T1 590 EAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVL 629 5688889999999999*********************977 PP == domain 2 score: -0.9 bits; conditional E-value: 5.3 TPR_20 24 arldlAlallaagrneeAleqLleilk 50 ++++l+ l++ g+ eeA++ l+ ++ FUN_000537-T1 653 IKYNLGRILAQLGKMEEAISVYLDAVE 679 78999999**********999888876 PP == domain 3 score: 4.1 bits; conditional E-value: 0.15 TPR_20 12 eaalaadpddlearldlAlallaagrneeAleqLl 46 ++ l+++pd l +l +A+ l++ g+ +eA + L+ FUN_000537-T1 712 KESLKSKPDHLPVHLTYAKYLNKMGKIAEAEK-LF 745 68899************************944.44 PP == domain 4 score: 4.6 bits; conditional E-value: 0.1 TPR_20 12 eaalaadpddlearldlAlallaagrneeAleqLleil 49 ++a++ +p++++a+++l++ +++g+ +eA ++ ++ l FUN_000537-T1 814 KKAAELQPQNPAAHMNLGAMFHMQGKLDEAEKSYVRAL 851 678889**********************9977666555 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 2.3 1.3e+03 11 24 .. 617 630 .. 614 631 .. 0.84 2 ? 5.7 0.0 0.05 28 9 24 .. 660 675 .. 657 679 .. 0.86 3 ? 0.3 0.1 2.8 1.6e+03 3 27 .. 691 715 .. 689 718 .. 0.85 4 ? 4.9 0.1 0.089 50 12 28 .. 734 750 .. 731 752 .. 0.87 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 2.3 PPR 11 cknGkleeAlelfk 24 + G +e+Al++++ FUN_000537-T1 617 SDMGHFEKALKVLR 630 6689*******985 PP == domain 2 score: 5.7 bits; conditional E-value: 0.05 PPR 9 gycknGkleeAlelfk 24 +++ Gk+eeA++++ FUN_000537-T1 660 ILAQLGKMEEAISVYL 675 5899*********996 PP == domain 3 score: 0.3 bits; conditional E-value: 2.8 PPR 3 ynslIsgycknGkleeAlelfkeMk 27 +n l +y+ +G+ eA++++ke + FUN_000537-T1 691 FNMLGEAYSAAGYQNEAERCYKESL 715 788889999999999******9965 PP == domain 4 score: 4.9 bits; conditional E-value: 0.089 PPR 12 knGkleeAlelfkeMke 28 k Gk+ eA++lfk+ ++ FUN_000537-T1 734 KMGKIAEAEKLFKKAQR 750 89***********9765 PP >> TPR_TmcB TmcB, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.2 0.0002 0.12 69 122 .. 703 755 .. 688 758 .. 0.88 2 ? 0.7 0.0 1.1 6.5e+02 75 121 .. 777 822 .. 769 827 .. 0.55 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.0002 TPR_TmcB 69 aikkaeeaYkkllklspnsvkvlrlYakFleevlnDkeaaakllkkaeeieeek 122 + ++ae+ Yk+ lk +p++ v Yak+l++ +a+kl+kka++++ ++ FUN_000537-T1 703 YQNEAERCYKESLKSKPDHLPVHLTYAKYLNKMG-KIAEAEKLFKKAQRLDAND 755 6799**************************9987.67899*********98765 PP == domain 2 score: 0.7 bits; conditional E-value: 1.1 TPR_TmcB 75 eaYkkllklspnsvkvlrlYakFleevlnDkeaaakllkkaeeieee 121 + + k + l p+ + + a +l e+ +++ +a++ +kka e++ + FUN_000537-T1 777 SMFAKAMVLAPEDFDIAFTAAGYLREIGKNQ-QAEDCYKKAAELQPQ 822 5555555555555555555566666666543.455666666555433 PP >> TPR_3 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 2.9 1.6e+03 10 21 .. 430 441 .. 429 443 .. 0.87 2 ? -1.2 0.0 6.5 3.7e+03 5 24 .. 576 595 .. 576 599 .. 0.82 3 ? -1.5 0.0 7.8 4.4e+03 7 24 .. 657 674 .. 655 675 .. 0.80 4 ? 1.3 0.4 1 5.9e+02 7 27 .. 728 748 .. 727 755 .. 0.72 5 ? 2.4 0.1 0.47 2.7e+02 15 34 .] 804 823 .. 803 823 .. 0.89 6 ? 9.8 0.0 0.0022 1.2 6 22 .. 829 845 .. 828 848 .. 0.86 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2.9 TPR_3 10 tfylkgkyqeAr 21 ++++k+ +q A+ FUN_000537-T1 430 SVQSKKSFQAAI 441 79*********8 PP == domain 2 score: -1.2 bits; conditional E-value: 6.5 TPR_3 5 yslAatfylkgkyqeArely 24 y l+ + + ++++eA++ y FUN_000537-T1 576 YNLGILLAEEKRFSEAVQSY 595 5677788899******9876 PP == domain 3 score: -1.5 bits; conditional E-value: 7.8 TPR_3 7 lAatfylkgkyqeArely 24 l+ + + gk +eA+ +y FUN_000537-T1 657 LGRILAQLGKMEEAISVY 674 56678899******9888 PP == domain 4 score: 1.3 bits; conditional E-value: 1 TPR_3 7 lAatfylkgkyqeArelyall 27 +A+ + +gk+ eA+ l++ + FUN_000537-T1 728 YAKYLNKMGKIAEAEKLFKKA 748 55555679********99755 PP == domain 5 score: 2.4 bits; conditional E-value: 0.47 TPR_3 15 gkyqeArelyallaiLdken 34 gk q+A++ y+ +a L+++n FUN_000537-T1 804 GKNQQAEDCYKKAAELQPQN 823 5669************9998 PP == domain 6 score: 9.8 bits; conditional E-value: 0.0022 TPR_3 6 slAatfylkgkyqeAre 22 l+a f+++gk++eA+ FUN_000537-T1 829 NLGAMFHMQGKLDEAEK 845 689************86 PP >> HAT_PRP39_N PRP39 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.00098 0.55 31 152 .. 705 783 .. 691 814 .. 0.61 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00098 HAT_PRP39_N 31 ekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYleflketlekedpeseekirelferavaavGldfrsdk 126 ++a+++y++ L++ P Ya++ ++ g++++ae++++++ + + W+hY +fl FUN_000537-T1 705 NEAERCYKESLKSKPDHLPVHLTYAKYLNKMGKIAEAEKLFKKAQRLDANDPAAWTHYGQFLF--------------------------------- 767 344555555555555555555556666666666666666666665555555556666666655................................. PP HAT_PRP39_N 127 lWdkYiefekeqkelkkvtaiydril 152 ++k+++++++++ +++ FUN_000537-T1 768 ----------DRKRVTEAASMFAKAM 783 ..........4444444444444443 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.8 0.00083 0.47 103 182 .. 527 599 .. 523 608 .. 0.84 2 ? -0.6 7.6 1.8 1e+03 79 168 .. 739 823 .. 663 853 .. 0.64 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00083 SNAP 103 iytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyekva 182 ++ ++g +aAk ++++++ ++ +++++A +aY++A y+++ a + ++ l ae++++++A+++ye+ + FUN_000537-T1 527 TLYRSGIPVNAAKALSNLGNVLSSQ-KRKREAEDAYRKALS-YRSNMA-----DTHYNLGILLAEEKRFSEAVQSYENAI 599 5667788889***************.*************98.454444.....44556778999************9976 PP == domain 2 score: -0.6 bits; conditional E-value: 1.8 SNAP 79 veAakcykksdpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsael 168 +eA k +kk + +A + + +t+ g+f k+ e a ++ k + + + +Aa + ++ + + +a+ c++k+A+l+ ++ FUN_000537-T1 739 AEAEKLFKKAQRLDANDP-----AAWTHYGQFLFDRKRVTEAASMFAKAMVLAPEDFDIAFTAAGYLREIGKNQQAEDCYKKAAELQPQN 823 344444444444444332.....1233344444444444444444443322222222222357777777778888888888888877654 PP >> TPR_WDR35 WD repeat-containing protein 35, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 2.4 1.4e+03 7 31 .. 541 565 .. 528 569 .. 0.61 2 ? 0.8 0.0 1.1 6.5e+02 14 34 .. 582 602 .. 579 615 .. 0.76 3 ? 6.9 0.5 0.015 8.5 10 33 .. 728 751 .. 726 754 .. 0.92 4 ? 1.0 0.1 1 5.7e+02 9 31 .. 761 783 .. 757 817 .. 0.78 5 ? -1.8 0.0 7.5 4.3e+03 11 32 .. 797 818 .. 793 829 .. 0.75 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 2.4 TPR_WDR35 7 LakyaahLlekeklleaveLYrkAg 31 L+ + L +++++ ea + YrkA FUN_000537-T1 541 LSNLGNVLSSQKRKREAEDAYRKAL 565 3344445666666666666777765 PP == domain 2 score: 0.8 bits; conditional E-value: 1.1 TPR_WDR35 14 LlekeklleaveLYrkAgkfl 34 L e+++ eav+ Y +A +f FUN_000537-T1 582 LAEEKRFSEAVQSYENAIHFR 602 45677777*********9984 PP == domain 3 score: 6.9 bits; conditional E-value: 0.015 TPR_WDR35 10 yaahLlekeklleaveLYrkAgkf 33 ya++L + +k+ ea L++kA++ FUN_000537-T1 728 YAKYLNKMGKIAEAEKLFKKAQRL 751 9********************986 PP == domain 4 score: 1.0 bits; conditional E-value: 1 TPR_WDR35 9 kyaahLlekeklleaveLYrkAg 31 +y + L ++++ +ea ++ kA FUN_000537-T1 761 HYGQFLFDRKRVTEAASMFAKAM 783 68888999999999999999995 PP == domain 5 score: -1.8 bits; conditional E-value: 7.5 TPR_WDR35 11 aahLlekeklleaveLYrkAgk 32 a +L e +k +a + Y+kA + FUN_000537-T1 797 AGYLREIGKNQQAEDCYKKAAE 818 5566777777777778888865 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.1 0.42 2.4e+02 22 34 .. 807 819 .. 799 821 .. 0.90 2 ? 5.8 0.1 0.055 31 1 27 [. 824 853 .. 824 853 .. 0.91 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.42 Sel1 22 ekAlewyekAAel 34 ++A +y+kAAel FUN_000537-T1 807 QQAEDCYKKAAEL 819 78999******98 PP == domain 2 score: 5.8 bits; conditional E-value: 0.055 Sel1 1 aeAqyrLG.ylylyGl.g.vpkDpekAlew 27 ++A+ +LG +++++G+ + +k + +Al++ FUN_000537-T1 824 PAAHMNLGaMFHMQGKlDeAEKSYVRALQL 853 689*************977********985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (880 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 960 (0.0375807); expected 510.9 (0.02) Passed bias filter: 602 (0.0235663); expected 510.9 (0.02) Passed Vit filter: 92 (0.00360149); expected 25.5 (0.001) Passed Fwd filter: 46 (0.00180074); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 45 [number of targets reported over threshold] # CPU time: 0.52u 0.39s 00:00:00.91 Elapsed: 00:00:00.46 # Mc/sec: 7798.14 // Query: FUN_000537-T2 [L=699] Description: FUN_000537 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-31 108.0 1.9 3.6e-31 107.4 0.8 2.0 1 TMTC_DUF1736 Protein O-mannosyl-transferase TMTC, DUF1736 2.1e-25 87.9 0.1 2.7e-06 27.4 0.1 4.5 4 TPR_1 Tetratricopeptide repeat 4.9e-22 76.7 0.2 0.0002 21.7 0.2 4.5 4 TPR_2 Tetratricopeptide repeat 2.6e-20 71.3 0.3 7.9e-05 23.0 0.0 4.8 4 TPR_8 Tetratricopeptide repeat 4e-18 65.3 0.1 3.6e-06 27.0 0.0 4.7 5 TPR_11 TPR repeat 1.6e-16 60.7 4.5 1.2e-06 29.1 0.1 4.0 4 TPR_12 Tetratricopeptide repeat 3.3e-15 55.3 0.1 0.0049 17.4 0.0 4.5 4 TPR_7 Tetratricopeptide repeat 2.7e-14 53.1 3.4 0.00013 22.4 0.4 4.5 4 TPR_10 Tetratricopeptide repeat 2e-12 47.8 0.1 4.1e-05 24.4 0.3 3.3 3 TPR_16 Tetratricopeptide repeat 2.8e-10 40.9 0.2 2.6e-05 24.9 0.0 3.4 3 TPR_19 Tetratricopeptide repeat 2e-09 37.4 2.8 0.045 14.5 0.0 4.9 4 TPR_17 Tetratricopeptide repeat 1.3e-07 32.1 0.5 0.46 11.8 0.0 4.3 4 TPR_14 Tetratricopeptide repeat 4.2e-06 27.5 0.1 6.3 8.2 0.0 4.5 4 TPR_6 Tetratricopeptide repeat 0.00017 22.4 1.7 0.024 15.5 0.0 3.1 3 TPR_Slam Surface lipoprotein assembly modifier, N-termi 0.0002 21.8 0.1 0.01 16.3 0.0 2.5 2 TPR_9 Tetratricopeptide repeat 0.0016 18.9 0.0 0.098 13.1 0.0 2.3 2 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.0055 17.5 1.4 0.72 10.7 0.1 3.0 3 ANAPC3 Anaphase-promoting complex, cyclosome, subunit 0.0058 16.9 0.4 6.4 7.0 0.0 3.0 2 TPR_21 Tetratricopeptide repeat-like domain 0.01 16.9 0.0 3.1 9.1 0.0 3.5 3 TPR_4 Tetratricopeptide repeat ------ inclusion threshold ------ 0.011 16.1 0.1 0.021 15.2 0.1 1.5 1 ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal 0.013 16.2 0.0 0.069 13.9 0.0 2.1 2 TPR_5 Tetratrico peptide repeat 0.02 15.2 0.1 2.3 8.5 0.2 2.8 2 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR dom 0.022 14.7 0.5 0.2 11.5 0.1 2.1 2 TPR_NPHP3 Nephrocystin-3 TPR domain 0.035 13.9 0.1 0.12 12.1 0.1 1.7 1 T7SS_EccA1_N T7SS, ESX-1 secretion system protein EccA1, N- 0.11 12.5 0.8 0.3 11.0 0.7 1.7 2 SNAP Soluble NSF attachment protein, SNAP 0.14 11.6 0.2 0.66 9.3 0.1 1.8 2 NatA_aux_su N-terminal acetyltransferase A, auxiliary subu Domain annotation for each model (and alignments): >> TMTC_DUF1736 Protein O-mannosyl-transferase TMTC, DUF1736 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.4 0.8 3.7e-34 3.6e-31 2 74 .. 279 351 .. 278 352 .. 0.97 Alignments for each domain: == domain 1 score: 107.4 bits; conditional E-value: 3.7e-34 TMTC_DUF1736 2 selPkFsesdnPaafseslltRaltynYllvlnlwlLllPssLsfDWsmgsipliesllDpRnlatllfylvl 74 +++P+Fs sdnP a+se++ltR lt+ Yl+v+n+wlL++P++LsfDWsm+s+pl+esllD+R++++l+fy+++ FUN_000537-T2 279 KQAPNFSPSDNPSANSEKFLTRLLTFVYLPVFNFWLLVCPRTLSFDWSMESVPLVESLLDVRCAIILMFYGFF 351 799*******************************************************************987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.1 2.8e-09 2.7e-06 1 31 [. 538 568 .. 538 571 .. 0.93 2 ! 24.8 0.0 1.9e-08 1.9e-05 1 32 [. 572 603 .. 572 605 .. 0.95 3 ! 14.6 0.0 3.2e-05 0.031 1 27 [. 606 632 .. 606 636 .. 0.90 4 ! 15.7 0.0 1.4e-05 0.014 5 32 .. 655 682 .. 651 684 .. 0.90 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 2.8e-09 TPR_1 1 akalynlGnayfklgkydeAleyyekALeln 31 akal nlGn++ ++++ eA+++y+kAL+ + FUN_000537-T2 538 AKALSNLGNVLSSQKRKREAEDAYRKALSYR 568 89**************************866 PP == domain 2 score: 24.8 bits; conditional E-value: 1.9e-08 TPR_1 1 akalynlGnayfklgkydeAleyyekALelnP 32 a+++ynlG ++ + +++ eA++ ye A+ +P FUN_000537-T2 572 ADTHYNLGILLAEEKRFSEAVQSYENAIHFRP 603 799*************************9988 PP == domain 3 score: 14.6 bits; conditional E-value: 3.2e-05 TPR_1 1 akalynlGnayfklgkydeAleyyekA 27 a a+ nlG ++ +g +++Al+ + A FUN_000537-T2 606 AAAHLNLGIVLSDMGHFEKALKVLRTA 632 789******************977666 PP == domain 4 score: 15.7 bits; conditional E-value: 1.4e-05 TPR_1 5 ynlGnayfklgkydeAleyyekALelnP 32 ynlG ++ +lgk +eA+ y A+e +P FUN_000537-T2 655 YNLGRILAQLGKMEEAISVYLDAVETRP 682 9*****************9999998777 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.2 2e-07 0.0002 1 30 [. 538 567 .. 538 570 .. 0.94 2 ! 18.8 0.0 1.7e-06 0.0017 1 32 [. 572 603 .. 572 605 .. 0.92 3 ! 14.9 0.0 3.1e-05 0.031 1 27 [. 606 632 .. 606 636 .. 0.93 4 ! 15.6 0.0 1.8e-05 0.018 5 32 .. 655 682 .. 652 684 .. 0.91 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 2e-07 TPR_2 1 aealynlGlayyklgdyeeAleayekAlel 30 a+al nlG+++ +++ eA++ay+kAl++ FUN_000537-T2 538 AKALSNLGNVLSSQKRKREAEDAYRKALSY 567 79**************************87 PP == domain 2 score: 18.8 bits; conditional E-value: 1.7e-06 TPR_2 1 aealynlGlayyklgdyeeAleayekAleldP 32 a+ +ynlG ++++ +++ eA++ ye A+ P FUN_000537-T2 572 ADTHYNLGILLAEEKRFSEAVQSYENAIHFRP 603 689************************97766 PP == domain 3 score: 14.9 bits; conditional E-value: 3.1e-05 TPR_2 1 aealynlGlayyklgdyeeAleayekA 27 a+a+ nlG ++ +g++e+Al+ ++ A FUN_000537-T2 606 AAAHLNLGIVLSDMGHFEKALKVLRTA 632 789********************9988 PP == domain 4 score: 15.6 bits; conditional E-value: 1.8e-05 TPR_2 5 ynlGlayyklgdyeeAleayekAleldP 32 ynlG+++++lg+ eeA+ y A+e P FUN_000537-T2 655 YNLGRILAQLGKMEEAISVYLDAVETRP 682 9**********************99777 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.2 1.9e-06 0.0019 1 32 [. 538 569 .. 538 571 .. 0.93 2 ! 12.4 0.0 0.0002 0.2 1 28 [. 572 599 .. 572 604 .. 0.91 3 ! 11.3 0.0 0.00046 0.45 2 30 .. 607 635 .. 606 637 .. 0.90 4 ! 23.0 0.0 8e-08 7.9e-05 3 32 .. 653 682 .. 651 684 .. 0.91 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 1.9e-06 TPR_8 1 aeayynlGliylklgdyeeAkeyyekaleldp 32 a+a+ nlG+++++++++ eA+ +y+kal+++ FUN_000537-T2 538 AKALSNLGNVLSSQKRKREAEDAYRKALSYRS 569 68999***********************9876 PP == domain 2 score: 12.4 bits; conditional E-value: 0.0002 TPR_8 1 aeayynlGliylklgdyeeAkeyyekal 28 a+++ynlG ++ + +++ eA+++ye a+ FUN_000537-T2 572 ADTHYNLGILLAEEKRFSEAVQSYENAI 599 6789*********************998 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00046 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 a++nlG +++++g +e+A ++++ a ++ FUN_000537-T2 607 AAHLNLGIVLSDMGHFEKALKVLRTASTI 635 6899********************99766 PP == domain 4 score: 23.0 bits; conditional E-value: 8e-08 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 + ynlG+i+ +lg++eeA+ +y a+e +p FUN_000537-T2 653 IKYNLGRILAQLGKMEEAISVYLDAVETRP 682 67************************9988 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.69 6.8e+02 27 39 .. 537 549 .. 536 552 .. 0.82 2 ! 19.3 0.1 9.3e-07 0.00092 1 39 [. 545 583 .. 545 585 .. 0.88 3 ! 27.0 0.0 3.7e-09 3.6e-06 6 42 .] 584 620 .. 581 620 .. 0.92 4 ? 1.7 0.0 0.3 3e+02 7 23 .. 619 635 .. 618 636 .. 0.86 5 ! 12.5 0.0 0.00013 0.13 1 25 [. 658 682 .. 658 689 .. 0.92 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.69 TPR_11 27 naeayynLGlayy 39 a a++nLG+++ FUN_000537-T2 537 AAKALSNLGNVLS 549 6899******986 PP == domain 2 score: 19.3 bits; conditional E-value: 9.3e-07 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayy 39 G+++ +q + eA aY+kAl ++++ a+ +ynLG +++ FUN_000537-T2 545 GNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLA 583 677777777889999********************9875 PP == domain 3 score: 27.0 bits; conditional E-value: 3.7e-09 TPR_11 6 eqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 e ++ eA+++Y++A+ ++P a a++nLG ++ +G FUN_000537-T2 584 EEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMG 620 67899***************************98887 PP == domain 4 score: 1.7 bits; conditional E-value: 0.3 TPR_11 7 qGkyeeAieaYkkAlkl 23 G +e+A++++++A + FUN_000537-T2 619 MGHFEKALKVLRTASTI 635 6899*********9876 PP == domain 5 score: 12.5 bits; conditional E-value: 0.00013 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldP 25 G+++ ++Gk eeAi +Y A++ +P FUN_000537-T2 658 GRILAQLGKMEEAISVYLDAVETRP 682 89******************99776 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.2 2.2e-06 0.0022 43 73 .. 536 566 .. 535 570 .. 0.92 2 ! 25.2 0.2 2e-08 2e-05 2 74 .. 571 635 .. 570 636 .. 0.88 3 ! 29.1 0.1 1.2e-09 1.2e-06 2 74 .. 605 680 .. 604 682 .. 0.91 4 ! 13.9 0.0 6.7e-05 0.066 4 32 .. 652 680 .. 649 698 .. 0.78 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 2.2e-06 TPR_12 43 ltatalrnLgrlylalgdyeeAlelleqale 73 + a al nLg +++ +++ +eA++++++al FUN_000537-T2 536 NAAKALSNLGNVLSSQKRKREAEDAYRKALS 566 5799*************************97 PP == domain 2 score: 25.2 bits; conditional E-value: 2e-08 TPR_12 2 tatalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +a +++nl+ +l++ +r+ eA + +e+a+ + p +a+a+ nLg++++ +g++e+Al+ l+ a i FUN_000537-T2 571 MADTHYNLGILLAEEKRFSEAVQSYENAIHFR--------PRLAAAHLNLGIVLSDMGHFEKALKVLRTASTI 635 68899999999999999999999999988666........559************************999765 PP == domain 3 score: 29.1 bits; conditional E-value: 1.2e-09 TPR_12 2 tatalnnlAavlrrlgrydeAlellekalela.erllGpdh..pltatalrnLgrlylalgdyeeAlelleqalei 74 +a+a++nl+ vl ++g +++Al+ l++a + l +p+h + + + +nLgr++ +lg+ eeA++ + +a+e FUN_000537-T2 605 LAAAHLNLGIVLSDMGHFEKALKVLRTASTISgHGLKDPKHhaHSIISIKYNLGRILAQLGKMEEAISVYLDAVET 680 578888***********************************5556677889*********************9986 PP == domain 4 score: 13.9 bits; conditional E-value: 6.7e-05 TPR_12 4 talnnlAavlrrlgrydeAlellekalel 32 ++ +nl+ +l++lg+++eA++ + a+e FUN_000537-T2 652 SIKYNLGRILAQLGKMEEAISVYLDAVET 680 56678999999999999999888888875 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.6 0.1 0.00017 0.16 1 26 [. 540 565 .. 540 571 .. 0.91 2 ! 9.2 0.0 0.002 2 1 28 [. 574 599 .. 574 606 .. 0.88 3 ! 10.3 0.0 0.00092 0.91 1 27 [. 608 634 .. 608 645 .. 0.87 4 ! 17.4 0.0 4.9e-06 0.0049 3 28 .. 655 680 .. 653 684 .. 0.86 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00017 TPR_7 1 aLsaLariyrklGdydeAirlyerlL 26 aLs+L+++++++ + +eA++ y+++L FUN_000537-T2 540 ALSNLGNVLSSQKRKREAEDAYRKAL 565 89**********************55 PP == domain 2 score: 9.2 bits; conditional E-value: 0.002 TPR_7 1 aLsaLariyrklGdydeAirlyerlLal 28 ++++L+ ++ + ++ eA++ ye+ a+ FUN_000537-T2 574 THYNLGILLAEEKRFSEAVQSYEN--AI 599 579********************9..55 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00092 TPR_7 1 aLsaLariyrklGdydeAirlyerlLa 27 a+++L+ +++ +G +++A+++++ + + FUN_000537-T2 608 AHLNLGIVLSDMGHFEKALKVLRTAST 634 789*******************99655 PP == domain 4 score: 17.4 bits; conditional E-value: 4.9e-06 TPR_7 3 saLariyrklGdydeAirlyerlLal 28 ++L+ri+ +lG+++eAi++y + ++ FUN_000537-T2 655 YNLGRILAQLGKMEEAISVYLDAVET 680 69*******************95544 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.4 1.3e-07 0.00013 2 30 .. 538 566 .. 537 570 .. 0.93 2 ! 8.0 0.1 0.0043 4.2 7 32 .. 577 602 .. 572 606 .. 0.92 3 ! 8.2 0.0 0.0037 3.6 6 28 .. 610 632 .. 605 640 .. 0.86 4 ! 11.8 0.0 0.00027 0.27 6 32 .. 655 681 .. 651 681 .. 0.92 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.3e-07 TPR_10 2 asslnnLanalraqgryeeAeelleeala 30 a +l+nL+n+l++q+r eAe+ +++al FUN_000537-T2 538 AKALSNLGNVLSSQKRKREAEDAYRKALS 566 679************************97 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0043 TPR_10 7 nLanalraqgryeeAeelleealair 32 nL+ +l + +r+ eA++ +e a+ r FUN_000537-T2 577 NLGILLAEEKRFSEAVQSYENAIHFR 602 9*********************9876 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0037 TPR_10 6 nnLanalraqgryeeAeelleea 28 nL+ +l+++g +e A++ l+ a FUN_000537-T2 610 LNLGIVLSDMGHFEKALKVLRTA 632 6****************999866 PP == domain 4 score: 11.8 bits; conditional E-value: 0.00027 TPR_10 6 nnLanalraqgryeeAeelleealair 32 nL+++l ++g+ eeA + +a+++r FUN_000537-T2 655 YNLGRILAQLGKMEEAISVYLDAVETR 681 5***********************987 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.3 4.2e-08 4.1e-05 3 60 .. 544 601 .. 542 607 .. 0.91 2 ? 3.0 0.0 0.2 2e+02 1 23 [. 610 632 .. 610 634 .. 0.91 3 ! 15.9 0.0 1.9e-05 0.019 34 62 .. 654 682 .. 652 685 .. 0.90 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 4.2e-08 TPR_16 3 laraalaagdyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalra 60 l++ + + + ++A+ a++ al ++ a+ +++lG +l++ +r+ eA++ y+ a+ FUN_000537-T2 544 LGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAIHF 601 7888999999***************************************999877755 PP == domain 2 score: 3.0 bits; conditional E-value: 0.2 TPR_16 1 lalaraalaagdyddAaaaleaa 23 l l+ + ++g+++ A++ l++a FUN_000537-T2 610 LNLGIVLSDMGHFEKALKVLRTA 632 578999**************987 PP == domain 3 score: 15.9 bits; conditional E-value: 1.9e-05 TPR_16 34 llglGlallrqgrlaeAaaayraalraap 62 ++lG++l+++g+++eA+ +y a++ p FUN_000537-T2 654 KYNLGRILAQLGKMEEAISVYLDAVETRP 682 69**********************98777 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.2 5e-05 0.049 8 46 .. 555 593 .. 548 593 .. 0.92 2 ! 24.9 0.0 2.7e-08 2.6e-05 1 51 [. 582 632 .. 582 635 .. 0.96 3 ! 7.6 0.0 0.007 6.9 27 56 .. 653 682 .. 651 690 .. 0.86 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 5e-05 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAea 46 eA ++++al++ + a+ +++L+ +l + +r++eA + FUN_000537-T2 555 REAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQ 593 79***********************************75 PP == domain 2 score: 24.9 bits; conditional E-value: 2.7e-08 TPR_19 1 llaegdydeAlalLeqalaedPdnaearllLArallalgrldeAealLaal 51 l +e+++ eA++ +e+a+ P a+a+l+L+ +l +g++++A ++L ++ FUN_000537-T2 582 LAEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTA 632 679*********************************************986 PP == domain 3 score: 7.6 bits; conditional E-value: 0.007 TPR_19 27 arllLArallalgrldeAealLaalpaadp 56 ++++L+r+l +lg+++eA+ + ++ + p FUN_000537-T2 653 IKYNLGRILAQLGKMEEAISVYLDAVETRP 682 6899***************99988887776 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.094 93 13 33 .. 538 558 .. 536 559 .. 0.88 2 ! 11.1 0.1 0.00056 0.55 1 34 [] 560 593 .. 560 593 .. 0.95 3 ! 14.5 0.0 4.6e-05 0.045 2 33 .. 595 626 .. 594 627 .. 0.96 4 ? 4.1 0.1 0.1 1e+02 17 33 .. 655 671 .. 655 672 .. 0.95 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.094 TPR_17 13 adayynLArlllnnGqleeAl 33 a+a+ nL+++l+ +++ eA+ FUN_000537-T2 538 AKALSNLGNVLSSQKRKREAE 558 789*********999999886 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00056 TPR_17 1 lylkaleldPnnadayynLArlllnnGqleeAlq 34 +y+kal+ n ad +ynL++ll + +++ eA+q FUN_000537-T2 560 AYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQ 593 599*************************999987 PP == domain 3 score: 14.5 bits; conditional E-value: 4.6e-05 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 y+ a+ P a a+ nL+++l+ +G++e+Al FUN_000537-T2 595 YENAIHFRPRLAAAHLNLGIVLSDMGHFEKAL 626 999****************************8 PP == domain 4 score: 4.1 bits; conditional E-value: 0.1 TPR_17 17 ynLArlllnnGqleeAl 33 ynL+r+l ++G+ eeA+ FUN_000537-T2 655 YNLGRILAQLGKMEEAI 671 8*************997 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.09 88 5 29 .. 542 566 .. 538 572 .. 0.86 2 ? 7.2 0.1 0.015 15 3 42 .. 574 613 .. 572 615 .. 0.90 3 ? 6.3 0.0 0.029 28 2 27 .. 607 632 .. 606 637 .. 0.90 4 ! 11.8 0.0 0.00047 0.46 5 36 .. 655 686 .. 652 695 .. 0.89 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.09 TPR_14 5 lalarallalGdpdeAlellerala 29 l+++l +++ eA++++++al+ FUN_000537-T2 542 SNLGNVLSSQKRKREAEDAYRKALS 566 568999*****************96 PP == domain 2 score: 7.2 bits; conditional E-value: 0.015 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlala 42 ++ l+ +l++ ++++eA++ +e a+ P ++a+l+l+ FUN_000537-T2 574 THYNLGILLAEEKRFSEAVQSYENAIHFRPRLAAAHLNLG 613 5678999********************99**999999997 PP == domain 3 score: 6.3 bits; conditional E-value: 0.029 TPR_14 2 eawlalarallalGdpdeAlellera 27 +a+l l+ +l G++++Al++l+ a FUN_000537-T2 607 AAHLNLGIVLSDMGHFEKALKVLRTA 632 6889999****************976 PP == domain 4 score: 11.8 bits; conditional E-value: 0.00047 TPR_14 5 lalarallalGdpdeAlelleralaldPddpe 36 + l+r+l++lG+ +eA+ ++ +a+++ P + e FUN_000537-T2 655 YNLGRILAQLGKMEEAISVYLDAVETRPPHYE 686 6799*********************9997766 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.079 78 2 28 .. 540 566 .. 539 570 .. 0.89 2 ? 5.2 0.0 0.055 54 3 27 .. 575 599 .. 573 603 .. 0.89 3 ? 3.4 0.0 0.21 2.1e+02 2 24 .. 608 630 .. 607 632 .. 0.92 4 ! 8.2 0.0 0.0064 6.3 4 28 .. 655 679 .. 654 683 .. 0.88 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.079 TPR_6 2 AllklalsylelgdkdeAkaalqrlik 28 Al +l+ + +++k eA +a+++ ++ FUN_000537-T2 540 ALSNLGNVLSSQKRKREAEDAYRKALS 566 777999*****************9876 PP == domain 2 score: 5.2 bits; conditional E-value: 0.055 TPR_6 3 llklalsylelgdkdeAkaalqrli 27 ++l+ ++ e +++ eA++ ++ i FUN_000537-T2 575 HYNLGILLAEEKRFSEAVQSYENAI 599 699*******99*********9876 PP == domain 3 score: 3.4 bits; conditional E-value: 0.21 TPR_6 2 AllklalsylelgdkdeAkaalq 24 A l+l+ + +g +++A+++l+ FUN_000537-T2 608 AHLNLGIVLSDMGHFEKALKVLR 630 7899****************997 PP == domain 4 score: 8.2 bits; conditional E-value: 0.0064 TPR_6 4 lklalsylelgdkdeAkaalqrlik 28 ++l++++ +lg+++eA++++ ++ FUN_000537-T2 655 YNLGRILAQLGKMEEAISVYLDAVE 679 89****************9987776 PP >> TPR_Slam Surface lipoprotein assembly modifier, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.2 0.00089 0.88 56 96 .. 547 587 .. 540 589 .. 0.92 2 ! 15.5 0.0 2.5e-05 0.024 50 94 .. 575 619 .. 574 628 .. 0.89 3 ? 0.8 0.0 0.91 8.9e+02 48 78 .. 652 682 .. 643 686 .. 0.83 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00089 TPR_Slam 56 larsqgnyaeAialYrellaekpdllpvrlqlAqaLfenkq 96 ++ sq++ +eA ++Yr+ l+ ++++ ++l + L e+k+ FUN_000537-T2 547 VLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKR 587 67899********************************9987 PP == domain 2 score: 15.5 bits; conditional E-value: 2.5e-05 TPR_Slam 50 kyaqAilarsqgnyaeAialYrellaekpdllpvrlqlAqaLfen 94 +y +il+ ++++++eA++ Y++ + +p l ++ l+l ++L + FUN_000537-T2 575 HYNLGILLAEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDM 619 78899**********************************999765 PP == domain 3 score: 0.8 bits; conditional E-value: 0.91 TPR_Slam 48 LlkyaqAilarsqgnyaeAialYrellaekp 78 +ky + ++ + g+++eAi+ Y ++++p FUN_000537-T2 652 SIKYNLGRILAQLGKMEEAISVYLDAVETRP 682 578999999999***********88888776 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 1.1e-05 0.01 3 57 .. 580 634 .. 578 649 .. 0.90 2 ? 2.8 0.0 0.18 1.7e+02 34 50 .. 656 672 .. 648 684 .. 0.87 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 1.1e-05 TPR_9 3 aiyireedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeayla 57 ++++e+++ +a + +e ++++P+ + + G+++ +g++e+Al+ L ++ FUN_000537-T2 580 ILLAEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTAST 634 67799*******************************************9998765 PP == domain 2 score: 2.8 bits; conditional E-value: 0.18 TPR_9 34 drGllyaqlgcleaAla 50 + G+++aqlg +e+A+ FUN_000537-T2 656 NLGRILAQLGKMEEAIS 672 689************85 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.1 1e+02 23 84 .. 537 599 .. 530 603 .. 0.78 2 ! 13.1 0.0 0.0001 0.098 10 85 .. 609 679 .. 605 689 .. 0.83 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.1 ARM_TT21 23 leeAlktLktAlklpg.kkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeai 84 +Al+ L + l+ ++ k+++++++++ s +s+ + +++l +l++ k+++eA + ++ai FUN_000537-T2 537 AAKALSNLGNVLSSQKrKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAI 599 567888888888887625556666777777888889999999999999999999998888886 PP == domain 2 score: 13.1 bits; conditional E-value: 0.0001 ARM_TT21 10 hlikakvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaie 85 hl + vl+ +g++e+Alk+L+tA +++g+ + +k+ + +s+ ++l ++l++l+k+eeA ++ +a+e FUN_000537-T2 609 HLNLGIVLSDMGHFEKALKVLRTASTISGHGLKD----PKHH-AHSIISIKYNLGRILAQLGKMEEAISVYLDAVE 679 6777899********************8864333....3332.34568999****************999998876 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.5 0.11 1.1e+02 24 81 .. 539 597 .. 534 598 .. 0.85 2 ! 8.0 0.5 0.0053 5.2 5 81 .. 554 631 .. 550 632 .. 0.89 3 ! 10.7 0.1 0.00073 0.72 4 80 .. 587 675 .. 584 677 .. 0.78 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.11 ANAPC3 24 edayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaLek 81 +++ l+++l ++++ ++A + rka ++++ + +y l+ l + k++ eA++ +e+ FUN_000537-T2 539 KALSNLGNVLSSQKRKREAEDAYRKAlSYRSNMADTHYNLGILLAEEKRFSEAVQSYEN 597 55566889999999999999999999888888889999999999999999999998886 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0053 ANAPC3 5 yknAiflaerllaaepespedayllAqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeAldaLek 81 ++A+ ++ ++l++ ++ ++ y l+ l +++++ +A++ ++a +++ +++ l+ +l +++++++Al++L+ FUN_000537-T2 554 KREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAiHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRT 631 57899999999*999999999999*********************8888888899999999999**********9975 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00073 ANAPC3 4 qyknAiflaerllaaepespedayl.lAqclflngqykrAyellrka.klneksl...........gcryllAqcllkLkkykeAldaLe 80 ++++A+ +e ++ + + + +a+l l+ +l +g +++A+++lr+a + ++ l + y l++ l +L+k++eA++++ FUN_000537-T2 587 RFSEAVQSYENAI-HFRPRLAAAHLnLGIVLSDMGHFEKALKVLRTAsTISGHGLkdpkhhahsiiSIKYNLGRILAQLGKMEEAISVYL 675 5667777778888.6777777777767999999999999999999997777776666666677777888888899999999999999876 PP >> TPR_21 Tetratricopeptide repeat-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.1 0.0097 9.5 153 175 .. 545 567 .. 536 578 .. 0.86 2 ! 7.0 0.0 0.0065 6.4 113 177 .. 606 682 .. 582 693 .. 0.68 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0097 TPR_21 153 GDilvaqgkldeAraAYqaAlaa 175 G +l +q ++ eA +AY++Al+ FUN_000537-T2 545 GNVLSSQKRKREAEDAYRKALSY 567 99******************975 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0065 TPR_21 113 avarlrLarvllaekkydeALktL.........eakkdeafaalvaelk...GDilvaqgkldeAraAYqaAlaale 177 a a+l L vl + +++++ALk+L k+++ a ++ +k G il++ gk++eA + Y +A+++ FUN_000537-T2 606 AAAHLNLGIVLSDMGHFEKALKVLrtastisghGLKDPKHHAHSIISIKynlGRILAQLGKMEEAISVYLDAVETRP 682 568999999*************9965544444322334444444444445559999999999999999999988765 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 4.8 4.7e+03 3 14 .. 574 585 .. 572 596 .. 0.75 2 ! 9.1 0.0 0.0032 3.1 1 25 [. 606 630 .. 606 631 .. 0.93 3 ? 2.9 0.0 0.34 3.4e+02 5 20 .. 655 670 .. 653 673 .. 0.90 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 4.8 TPR_4 3 allaLArallal 14 ++++L+ +l++ FUN_000537-T2 574 THYNLGILLAEE 585 799*****9976 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0032 TPR_4 1 arallaLArallalGdldeAralle 25 a+a+l+L+ +l + G+++ A+ +l+ FUN_000537-T2 606 AAAHLNLGIVLSDMGHFEKALKVLR 630 68******************98887 PP == domain 3 score: 2.9 bits; conditional E-value: 0.34 TPR_4 5 laLArallalGdldeA 20 ++L+r l++lG +eA FUN_000537-T2 655 YNLGRILAQLGKMEEA 670 79*********98888 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 2.1e-05 0.021 101 158 .. 544 601 .. 521 632 .. 0.90 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.1e-05 ARM_TT21_C 101 ladiyiqsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWkl 158 l ++ +++++ +Ae+ +k+l+y ++ a lG++ +e+++++A+++Ye+A ++ FUN_000537-T2 544 LGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILLAEEKRFSEAVQSYENAIHF 601 6777778899999******************************************876 PP >> TPR_5 Tetratrico peptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 4.7 4.7e+03 13 28 .. 550 565 .. 538 570 .. 0.70 2 ? 13.9 0.0 7.1e-05 0.069 19 108 .. 590 685 .. 584 691 .. 0.79 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 4.7 TPR_5 13 svGhedkavplYrraL 28 s ++ +a++ Yr+aL FUN_000537-T2 550 SQKRKREAEDAYRKAL 565 4455667888888887 PP == domain 2 score: 13.9 bits; conditional E-value: 7.1e-05 TPR_5 19 kavplYrraLaaGLagarrrqatiqLassLRnlGeleealaLLraeltrggdeldd.........alaaflaLvLadlgrereavailllalaehl 105 +av+ Y++a++ +r a + L L +G+ e+al++Lr t +g++l+d +++ l +La+lg+ +ea+++ l+a+ FUN_000537-T2 590 EAVQSYENAIHF---RPRLAAAHLNLGIVLSDMGHFEKALKVLRTASTISGHGLKDpkhhahsiiSIKYNLGRILAQLGKMEEAISVYLDAVETRP 682 677777777763...57777888999999******************999999988444433222234445669******************9988 PP TPR_5 106 prY 108 p Y FUN_000537-T2 683 PHY 685 888 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.2 0.0024 2.3 56 141 .. 544 626 .. 536 635 .. 0.58 2 ? 2.7 0.0 0.15 1.4e+02 56 81 .. 657 682 .. 655 688 .. 0.88 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0024 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAi 141 LG + s+++ ++A +A++kAl+ + n ++ ++ +L +e+ ++A + ++++++ p+ a l++ + g++e+A+ FUN_000537-T2 544 LGNVLSSQKRKREAEDAYRKALSYRSNMADTHYNLGILL---AEEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKAL 626 666666777777777777777666666666655554333...34444555555555555555555555555555555555555555 PP == domain 2 score: 2.7 bits; conditional E-value: 0.15 TPR_CcmH_CycH 56 LGriglslndaetAiqAfekAlklap 81 LGri +l+++e+Ai+ + A++ +p FUN_000537-T2 657 LGRILAQLGKMEEAISVYLDAVETRP 682 9**************99999988877 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.1 0.51 5.1e+02 141 174 .. 538 571 .. 533 586 .. 0.71 2 ? 11.5 0.1 0.0002 0.2 93 171 .. 600 681 .. 580 691 .. 0.80 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.51 TPR_NPHP3 141 arslhqLagLyaqwgkfstaealykqaleiyena 174 a++l +L ++ + ++ + ae+ y++al+ n+ FUN_000537-T2 538 AKALSNLGNVLSSQKRKREAEDAYRKALSYRSNM 571 5677777777777777778888888888765554 PP == domain 2 score: 11.5 bits; conditional E-value: 0.0002 TPR_NPHP3 93 ltlakvadlyealGrflkdlgllsqalpaLqraLeiRetal.dPDhP..lvarslhqLagLyaqwgkfstaealykqaleiy 171 + ++a + lG l d+g ++al+ L+ a i l dP h ++ + +++L ++ aq gk + a ++y +a+e FUN_000537-T2 600 HFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTASTISGHGLkDPKHHahSIISIKYNLGRILAQLGKMEEAISVYLDAVETR 681 335688999999************************98877699986335778899**********************9875 PP >> T7SS_EccA1_N T7SS, ESX-1 secretion system protein EccA1, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.00013 0.12 109 196 .. 548 634 .. 526 683 .. 0.85 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00013 T7SS_EccA1_N 109 liaagdyaeAeevldeapk.agdeeivayvravlhfrtqrWpDVlaalarsaewedeylaaaakvmvGtAlaqLGlFeeAlrrleeaed 196 l ++++ +eAe++ +a + + +y ++l + +r ++ ++ +++ + + ++ aaa++ +G+ l +G Fe+Al+ l++a + FUN_000537-T2 548 LSSQKRKREAEDAYRKALSyRSNMADTHYNLGILLAEEKRFSEAVQSYENAIHFRPRL--AAAHLNLGIVLSDMGHFEKALKVLRTAST 634 6778999999999998765245566778********************9999999886..799*******************9998854 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.7 0.00031 0.3 103 182 .. 527 599 .. 523 610 .. 0.84 2 ? -2.0 0.0 2.8 2.7e+03 117 143 .. 654 679 .. 618 680 .. 0.76 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00031 SNAP 103 iytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyekva 182 ++ ++g +aAk ++++++ ++ +++++A +aY++A y+++ a + ++ l ae++++++A+++ye+ + FUN_000537-T2 527 TLYRSGIPVNAAKALSNLGNVLSSQ-KRKREAEDAYRKALS-YRSNMA-----DTHYNLGILLAEEKRFSEAVQSYENAI 599 5667888889***************.*************98.454444.....44556778999************9976 PP == domain 2 score: -2.0 bits; conditional E-value: 2.8 SNAP 117 kkeiaelyekelqdlekAieaYeqAad 143 k +++ ++ + +++e+Ai+ Y +A + FUN_000537-T2 654 KYNLGRILAQL-GKMEEAISVYLDAVE 679 45666777655.788888888877765 PP >> NatA_aux_su N-terminal acetyltransferase A, auxiliary subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.1 0.00067 0.66 176 253 .. 550 633 .. 534 639 .. 0.76 2 ? -0.3 0.0 0.55 5.4e+02 37 71 .. 650 684 .. 638 692 .. 0.79 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00067 NatA_aux_su 176 sesdnedsekepesallwtlyflAqhydk......lgsrekAleyidkaiehtptlvelymtKarilkhaGdlqkAaevmeear 253 s++++ ++e+ ++al + ++ hy+ ++ ++A++ ++ai+ p+l +++ + +l +G ++kA +v+ +a FUN_000537-T2 550 SQKRKREAEDAYRKALSYRSNMADTHYNLgillaeEKRFSEAVQSYENAIHFRPRLAAAHLNLGIVLSDMGHFEKALKVLRTAS 633 23333556677778888888888888886654321444559**************************************99886 PP == domain 2 score: -0.3 bits; conditional E-value: 0.55 NatA_aux_su 37 klavketkaelllkLgrkeeAeatyeaLlernpen 71 +++k +++l +Lg++eeA ++y + +e p + FUN_000537-T2 650 IISIKYNLGRILAQLGKMEEAISVYLDAVETRPPH 684 56777788999*************99888877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (699 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 948 (0.037111); expected 510.9 (0.02) Passed bias filter: 558 (0.0218438); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 26 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 6916.57 // Query: FUN_000538-T1 [L=281] Description: FUN_000538 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-22 80.6 20.9 4.4e-15 56.4 5.9 2.1 2 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.22 11.8 3.2 0.35 11.1 3.2 1.4 1 FA_desaturase Fatty acid desaturase 5.3 7.5 6.9 2 8.8 0.3 2.5 2 Cortexin Cortexin of kidney Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 5.9 5.1e-19 4.4e-15 3 121 .. 1 120 [. 1 127 [. 0.86 2 ! 29.9 7.9 6e-11 5.1e-07 155 260 .] 128 237 .. 120 237 .. 0.81 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 5.1e-19 xxxxxxxxx..xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 3 llVilvilr..nkklrt.ptnifllnLavaDllvlllvlpfalvyallegdwvfgevl..CklvtaldvvnltasillltaisiDRYlaIvkplky 93 +l+++vi++ nk+lr+ + n ++lnLavaDl+++ l++ ++v ++l ++ + ++v+ ++v++ +++++tas+l++ ++ +RYl+I+ ky FUN_000538-T1 1 MLICWVIVKdpNKELRSlEFNRLVLNLAVADLITG-LITEPSFVAFHL-REIQGKQVMryIAIVHMAYFISCTASLLSISSLATERYLSITS--KY 92 589******88899***999***************.666666666664.666666666556899***************************9..55 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppl 121 +ri +++r++++ + +Wv+a++ s+ + FUN_000538-T1 93 RRIFSRSRTIIWSISIWVFAIASSFAYF 120 66*******************9998765 PP == domain 2 score: 29.9 bits; conditional E-value: 6e-11 xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 155 lllsvlgfll.pllvilvcyvrilrtlrksakkekskkkksarker....kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallit 245 ++++v ++ + v++++y+ri++ l+ + + ++++ ++ ++++ ka++ ++v++vf++c l +++ +ll++ +++++++++ ++ FUN_000538-T1 128 VFVFVNLIVIaSFGVMTYSYIRIYQSLHVEGSVAAHTGNRLMERRLiyekKATRSFFLVLFVFICCNLSSCA-MVYGILLCDVCNCDVIHWLRDFQ 222 333444444469*****************999998844444333336777*****************98655.88888889*************** PP xxxxxxxxxxxxxxx RF 7tm_1 246 lllayvnsclNPiiY 260 l a+vn++ N ++Y FUN_000538-T1 223 FLTALVNCAANQFLY 237 ***********9988 PP >> FA_desaturase Fatty acid desaturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 3.2 4.1e-05 0.35 116 211 .. 92 189 .. 30 195 .. 0.55 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 4.1e-05 FA_desaturase 116 warrlarrkrpiksrrrrwrllaalllllawlglwlallllagllll.....lwllpllvllfllalvf.........nyleHyggdwgerpvett 197 ++r ++r ++ i+s+ w++ a ++ +++++++++++++ l++ ++ + ++ + ++ H+g++ er++ + FUN_000538-T1 92 YRRIFSRSRTIIWSISI-WVFAIASSFAY-FAIGFYTFVFVFVNLIViasfgVMTYSYI---------RiyqslhvegSVAAHTGNRLMERRLIYE 176 33344444444433332.33333333332.23333333333333222233223333333.........2555666666999999988888888888 PP FA_desaturase 198 rsinspswllnllt 211 + +s +l l++ FUN_000538-T1 177 KKAT-RSFFLVLFV 189 8877.666666654 PP >> Cortexin Cortexin of kidney # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 1.6 0.061 5.2e+02 28 53 .. 124 149 .. 117 159 .. 0.73 2 ? 8.8 0.3 0.00024 2 4 43 .. 159 198 .. 155 207 .. 0.86 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.061 Cortexin 28 fvilLlifLglLivrCfriLLDPYss 53 f ++++f+ l+++ f ++ Y + FUN_000538-T1 124 FYTFVFVFVNLIVIASFGVMTYSYIR 149 66777888888888888777666655 PP == domain 2 score: 8.8 bits; conditional E-value: 0.00024 Cortexin 4 salapsgnevsavslsleqktvfafvilLlifLglLivrC 43 s +a +gn +++ l e+k++ +f ++L++f+ + C FUN_000538-T1 159 SVAAHTGNRLMERRLIYEKKATRSFFLVLFVFICCNLSSC 198 5577889*************************98776666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (281 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1189 (0.0465453); expected 510.9 (0.02) Passed bias filter: 355 (0.013897); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2831.43 // Query: FUN_000539-T1 [L=115] Description: FUN_000539 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 552 (0.0216089); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1174.78 // Query: FUN_000540-T1 [L=321] Description: FUN_000540 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-23 82.2 21.6 3.6e-21 76.3 21.6 2.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 8.7 6.6 7.8 12 6.2 6.7 1.8 2 VIT1 VIT family Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.3 21.6 2.8e-25 3.6e-21 1 260 [] 35 273 .. 35 273 .. 0.80 Alignments for each domain: == domain 1 score: 76.3 bits; conditional E-value: 2.8e-25 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCk.lvtaldvvnltasillltaisiDRYlaIvkplky 93 gNll++++i++ n l+++ n+++lnLa+aD +++++ p+ ++y++ + ++ + + lv++ ++v++tasil+++a+s DRYla++ + + FUN_000540-T1 35 GNLLICWAIIKdpNGDLKSSFNYLILNLAIADCFIGVVTEPVFVWYHSS-EAIKYEVLELRwLVYMSYFVTSTASILSIVALSTDRYLALTSTTIR 129 8**********5555599******************9999**9999994.55555554444166667888999*******************8887 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 +++ ++a+++ +++W+++ l ++ +++ +t + + ++ +++ +fll + +i ++ +++++ ++a ++ FUN_000540-T1 130 --RVSSKKAAIVSMAIWFFSGGLPFLYFVVG-FYTL---------AFIY----------ANIAIIMTTFLLAFYFIRIVQRLTAHEKLMRAVLRRG 203 ..7899**************99888888754.2222.........2333..........4455555566666666666666666655555555555 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++k + e+ka+k + ++++f++c +P +++ + l ++++s+++++++ ++ +l ++vns+ N ++Y FUN_000540-T1 204 DQRKGLSMEKKATKSFFRILIFFFVCSFPSCVMIYVINL-CATCSCDIIHWFRDLQYLSILVNSACNQFLY 273 6667788899**********************9999998.7888999********************8888 PP >> VIT1 VIT family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 6.7 0.0009 12 131 195 .. 131 199 .. 99 203 .. 0.66 2 ? -0.4 0.0 0.093 1.2e+03 103 155 .. 186 237 .. 182 248 .. 0.53 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0009 VIT1 131 asplkaAltsflsfllggliPllpyllvp...svaaalvvsivltllallllGavkarltgasv.lrsa 195 s kaA++s++ ++ g +P l +++ + + a ++ i+ t l + + +++rlt ++ +r++ FUN_000540-T1 131 VSSKKAAIVSMAIWFFSGGLPFLYFVVGFytlAFIYANIAIIMTTFLLAFYFIRIVQRLTAHEKlMRAV 199 56789******************9997552333444444444444444444444555555555534444 PP == domain 2 score: -0.4 bits; conditional E-value: 0.093 VIT1 103 vaellknkdalldammreelg...ideseeeasplkaAltsflsfllggliPllpy 155 v++l++++ +l++a++r + ++ e+++ k+ + + ++f+++++ + + FUN_000540-T1 186 VQRLTAHE-KLMRAVLRRGDQrkgLS---MEKKATKSFFRILIFFFVCSFPSCVMI 237 55555544.45777777554422244...223455666666666666655444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1367 (0.0535134); expected 510.9 (0.02) Passed bias filter: 521 (0.0203954); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3184.20 // Query: FUN_000541-T1 [L=398] Description: FUN_000541 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-19 69.4 32.7 1.4e-14 54.7 10.0 2.5 3 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.2 0.17 4.4e+03 42 78 .. 36 72 .. 29 75 .. 0.59 2 ! 54.7 10.0 5.6e-19 1.4e-14 1 122 [. 78 199 .. 78 205 .. 0.82 3 ! 24.6 10.5 8.5e-10 2.2e-05 154 260 .] 206 316 .. 199 316 .. 0.83 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 0.17 xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF 7tm_1 42 lvyallegdwvfgevlCk.lvtaldvvnltasilllta 78 ++ a+ + + +f ++lC+ ++ l + lta i l+++ FUN_000541-T1 36 AIDAS-HATMPFIKHLCEeTWPPLSLSVLTAAIALVLC 72 44444.67777777777435666666666666666555 PP == domain 2 score: 54.7 bits; conditional E-value: 5.6e-19 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklv..taldvvnltasillltaisiDRYlaIvkplk 92 gNll+++++l+ +kkl+++ n+f+l La++Dl+v++++ p+ + ++ +++ v+ +++ ++ ++++ tas+l+l+a+++DRYl+++ k FUN_000541-T1 78 GNLLLCIAMLKdpYKKLKNSFNCFVLQLALSDLVVGTITEPLFV-IFH-SREALGYPVMQNVWliHLSFFFSYTASLLSLAALTLDRYLTVMSYHK 171 8**********8999*********************66666666.455.2444444455555422778999999******************9666 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppll 122 + + + ++++ +++Wv+++l+s+ ++ FUN_000541-T1 172 R--ALSTSGVILISILIWVISILFSCFYFV 199 6..6678899999************98877 PP == domain 3 score: 24.6 bits; conditional E-value: 8.5e-10 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 154 tlllsvlgfllpllvilvcyvrilrtlrksakkeks.....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetalli 244 ++l++ ++++ +++++++yvri ++l+++ ++ + k ++++ er + + +++++f++c +P ++++ + + ++++s++lv+++ ++ FUN_000541-T1 206 AFLFNNAALIIIITILTFTYVRIHQRLKRQITRWDWhcqtqVKLQAMSMERNLNRGFYIILGIFLVCLFPSVVMMYIVNF-CDTCSCTLVHWFRDL 300 45555566777899999**************999885555433334445669999******************9999998.8888999******** PP xxxxxxxxxxxxxxxx RF 7tm_1 245 tlllayvnsclNPiiY 260 + l+ +vn+ lN ++Y FUN_000541-T1 301 VCLFPLVNCSLNQFLY 316 ************9988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (398 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1573 (0.0615776); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.40s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3814.58 // Query: FUN_000542-T1 [L=376] Description: FUN_000542 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-26 90.5 4.1 1.6e-25 89.8 4.1 1.4 1 HMG_box HMG (high mobility group) box 1.7e-09 38.7 1.2 3.1e-09 37.9 1.2 1.4 1 HMG_box_2 HMG-box domain 0.00054 20.3 1.0 0.0015 18.9 1.0 1.8 1 HMG_WDHD1 WDHD1 HMG box Domain annotation for each model (and alignments): >> HMG_box HMG (high mobility group) box # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 89.8 4.1 1.8e-29 1.6e-25 1 69 [] 32 100 .. 32 100 .. 0.99 Alignments for each domain: == domain 1 score: 89.8 bits; conditional E-value: 1.8e-29 HMG_box 1 pkRplsaFflfsqeqraklkaenPdlknaeiskklgekWkelseeeKkkYeekaekekakyekampeyk 69 +kRp+++F+++ +++r+k+++enP+l+naeisk lg+ W+el+ +eK+++ ekae+++ +++k++p+y+ FUN_000542-T1 32 VKRPMNSFMIWAKIMRRKFAEENPKLHNAEISKLLGKAWNELTTKEKRPFVEKAERLRIRHMKEHPNYR 100 69******************************************************************6 PP >> HMG_box_2 HMG-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 1.2 3.6e-13 3.1e-09 5 71 .. 33 99 .. 30 100 .. 0.97 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 3.6e-13 HMG_box_2 5 KaarnAYalFvqeeqpelkrknpvievaevskkcSekWrnlseeeKekYaekAredkerydremkty 71 K+++n+++++++ ++ + ++np + ae+sk++++ W+ l +eK ++ ekA + r +e ++y FUN_000542-T1 33 KRPMNSFMIWAKIMRRKFAEENPKLHNAEISKLLGKAWNELTTKEKRPFVEKAERLRIRHMKEHPNY 99 99*************************************************************9998 PP >> HMG_WDHD1 WDHD1 HMG box # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 1.0 1.8e-07 0.0015 1 51 [] 35 84 .. 35 84 .. 0.95 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 1.8e-07 HMG_WDHD1 1 PktgFqLWLeenRsqileenPDlsdeadiiKegmsrfRsLsseeRkvWteK 51 P ++F +W R ++ eenP l a+i+K ++ + L+++e++ + eK FUN_000542-T1 35 PMNSFMIWAKIMRRKFAEENPKL-HNAEISKLLGKAWNELTTKEKRPFVEK 84 7899******************9.699******************999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (376 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 590 (0.0230965); expected 510.9 (0.02) Passed bias filter: 475 (0.0185946); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.36s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3637.33 // Query: FUN_000543-T1 [L=76] Description: FUN_000543 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (76 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 398 (0.0155803); expected 510.9 (0.02) Passed bias filter: 335 (0.0131141); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 777.62 // Query: FUN_000544-T1 [L=255] Description: FUN_000544 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-13 50.0 16.1 2.1e-09 36.8 3.4 2.3 2 DUF7885 Leucine Rich Repeat Domain of unknown functio 2.9e-10 40.6 10.8 0.00076 20.1 0.8 4.3 5 LRR_4 Leucine Rich repeats (2 copies) 1.4e-09 37.8 11.9 0.13 12.9 0.1 6.8 6 LRR_6 Leucine Rich repeat 3.9e-09 37.0 13.9 0.00017 21.8 4.3 3.1 3 LRR_At5g56370 FBD-associated F-box protein At5g56370, LRR r 0.00076 20.1 5.4 0.57 10.8 0.2 3.3 4 LRR_Zer-1 Zer-1-like, Leucine-rich repeats ------ inclusion threshold ------ 0.034 14.7 8.7 33 5.8 0.1 5.7 5 LRR_1 Leucine Rich Repeat 0.038 14.3 0.1 0.2 11.9 0.0 2.0 2 DNA_pol_A_exo1 3'-5' exonuclease 0.092 13.6 0.3 0.86 10.5 0.0 2.4 2 PRANC PRANC domain 0.29 11.4 3.3 12 6.2 0.1 2.9 2 LRR_8 Leucine rich repeat Domain annotation for each model (and alignments): >> DUF7885 Leucine Rich Repeat Domain of unknown function (DUF7885) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 5.1 2.2e-07 0.00064 341 413 .. 60 136 .. 34 139 .. 0.79 2 ! 36.8 3.4 7.3e-13 2.1e-09 340 415 .. 139 217 .. 135 242 .. 0.90 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 2.2e-07 DUF7885 341 CknlevldlsgCrsiadsGlasisklskltlldlaGa.....ditdaGlsalGnGsspisslclrgCkritdrGiasl 413 +l l+l Cr i+dsGlas++ l ldl + dit +G+ + + ++++++ lr C ++d i +l FUN_000544-T1 60 HPSLRDLELCECR-ISDSGLASLCVCKNLRKLDLNATknsrdDITSEGVIKVFTSCCQLQTVYLRRCINVSDTAIITL 136 4567777788887.9*********9999999999654344449*****************************999877 PP == domain 2 score: 36.8 bits; conditional E-value: 7.3e-13 DUF7885 340 sCknlevldlsgCrsiadsGlasisklsk.ltlldlaGaditdaGlsalGnGssp..isslclrgCkritdrGiaslll 415 C++le l+l gC +i d+ l ++k +k l +l+++ + +td+G+ l +G+++ i+ +++ C itd i ll FUN_000544-T1 139 NCRHLEHLNLCGCINITDTSLHVLAKNCKfLQSLNISKTKVTDNGIMQLTTGKCRqsIKEVQVSHCIHITDASIEALLA 217 6****************************6799*******************9974477789999*********99986 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.8 2.7e-07 0.00076 1 39 [. 61 102 .. 61 109 .. 0.79 2 ? 3.9 0.0 0.035 99 19 38 .. 111 130 .. 99 138 .. 0.73 3 ! 15.2 0.6 9.8e-06 0.028 2 40 .. 116 158 .. 115 160 .. 0.84 4 ! 17.7 2.1 1.6e-06 0.0045 2 38 .. 142 181 .. 141 184 .. 0.87 5 ? 1.1 0.0 0.26 7.4e+02 3 36 .. 196 233 .. 194 237 .. 0.70 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 2.7e-07 LRR_4 1 pnLetLdLsnNritdidp..lsk.LpnLetLdLsg.Nnkitdl 39 p+L+ L L +ri+d ++ l + ++nL++LdL+ n +d+ FUN_000544-T1 61 PSLRDLELCECRISDSGLasL-CvCKNLRKLDLNAtKNSRDDI 102 79*************999643.55*********5523444665 PP == domain 2 score: 3.9 bits; conditional E-value: 0.035 LRR_4 19 lskLpnLetLdLsgNnkitd 38 + ++ +L+t++L ++ +++d FUN_000544-T1 111 FTSCCQLQTVYLRRCINVSD 130 558999******88866665 PP == domain 3 score: 15.2 bits; conditional E-value: 9.8e-06 LRR_4 2 nLetLdLsnN.ritdidpls...kLpnLetLdLsgNnkitdls 40 +L+t +L+ + +++d + ++ +Le+L+L g+ +itd s FUN_000544-T1 116 QLQTVYLRRCiNVSDTAIITlteNCRHLEHLNLCGCINITDTS 158 799999998779999888444468************9999975 PP == domain 4 score: 17.7 bits; conditional E-value: 1.6e-06 LRR_4 2 nLetLdLsnN.ritdidp..lsk.LpnLetLdLsgNnkitd 38 +Le+L+L ++ +itd ++ l+k ++ L++L++s + k+td FUN_000544-T1 142 HLEHLNLCGCiNITDTSLhvLAKnCKFLQSLNISKT-KVTD 181 7*******999*******998866*********554.7776 PP == domain 5 score: 1.1 bits; conditional E-value: 0.26 LRR_4 3 LetLdLsnN.ritdidp..lsk.LpnLetLdLsgNnki 36 ++ s++ +itd + l +p+ +L g++++ FUN_000544-T1 196 IKEVQVSHCiHITDASIeaLLAlCPRINILIFDGCPHV 233 56677787778998888665566999888855666655 PP >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.1 0.0 0.00017 0.48 3 24 .] 61 82 .. 60 82 .. 0.94 2 ? 2.9 0.1 0.072 2e+02 2 11 .. 84 93 .. 83 94 .. 0.89 3 ? 0.3 0.0 0.49 1.4e+03 14 22 .. 101 109 .. 101 111 .. 0.86 4 ! 7.0 1.1 0.0035 9.9 1 18 [. 139 157 .. 139 163 .. 0.80 5 ! 12.9 0.1 4.6e-05 0.13 2 21 .. 166 185 .. 165 187 .. 0.91 6 ? 4.3 0.0 0.025 71 4 23 .. 195 215 .. 194 216 .. 0.89 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00017 LRR_6 3 ttLteLdLsgNdIgDeGleaLa 24 ++L+ L+L ++I+D+Gl +L+ FUN_000544-T1 61 PSLRDLELCECRISDSGLASLC 82 79******************98 PP == domain 2 score: 2.9 bits; conditional E-value: 0.072 LRR_6 2 nttLteLdLs 11 + +L++LdL+ FUN_000544-T1 84 CKNLRKLDLN 93 89******95 PP == domain 3 score: 0.3 bits; conditional E-value: 0.49 LRR_6 14 dIgDeGlea 22 dI+ eG+++ FUN_000544-T1 101 DITSEGVIK 109 79*****97 PP == domain 4 score: 7.0 bits; conditional E-value: 0.0035 LRR_6 1 hnttLteLdLsgNd.IgDe 18 ++++L++L+L g+ I+D+ FUN_000544-T1 139 NCRHLEHLNLCGCInITDT 157 59********999778876 PP == domain 5 score: 12.9 bits; conditional E-value: 4.6e-05 LRR_6 2 nttLteLdLsgNdIgDeGle 21 + L++L++s +++D G++ FUN_000544-T1 166 CKFLQSLNISKTKVTDNGIM 185 899***************97 PP == domain 6 score: 4.3 bits; conditional E-value: 0.025 LRR_6 4 tLteLdLsgNd.IgDeGleaL 23 +++e+ +s++ I+D +eaL FUN_000544-T1 195 SIKEVQVSHCIhITDASIEAL 215 7899******99****99998 PP >> LRR_At5g56370 FBD-associated F-box protein At5g56370, LRR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.8 2.4e-05 0.069 56 98 .. 56 97 .. 37 110 .. 0.78 2 ! 21.8 4.3 6.1e-08 0.00017 11 97 .. 85 178 .. 85 204 .. 0.72 3 ! 9.5 0.1 0.00034 0.98 69 97 .. 203 231 .. 194 245 .. 0.79 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.4e-05 LRR_At5g56370 56 raasFpnLreLgLsrvsiserdLhalLarcpvLesLsllgsrn 98 +++ p Lr+L+L+++ is++ L++l c+ L++L l + +n FUN_000544-T1 56 EKVLHPSLRDLELCECRISDSGLASL-CVCKNLRKLDLNATKN 97 5566799****************995.789*****99876544 PP == domain 2 score: 21.8 bits; conditional E-value: 6.1e-08 LRR_At5g56370 11 kgvqeLvlvnrpwpldlp....lpasllrcaslrrlylgvwr.f.dtdalpraasFpnLreLgLs.rvsiserdLhalLarcpvLesLsllgsr 97 k++++L+l + ++d + + + +c +l+++yl + + dt+ ++ + + +L++L+L+ +++i++++Lh l ++c+ L+sL++ + + FUN_000544-T1 85 KNLRKLDLNATKNSRDDItsegVIKVFTSCCQLQTVYLRRCInVsDTAIITLTENCRHLEHLNLCgCINITDTSLHVLAKNCKFLQSLNISKTK 178 567777776555554432112256667799********9875345778888899**********94567*******************997543 PP == domain 3 score: 9.5 bits; conditional E-value: 0.00034 LRR_At5g56370 69 srvsiserdLhalLarcpvLesLsllgsr 97 ++++i++++++alLa cp +++L + g+ FUN_000544-T1 203 HCIHITDASIEALLALCPRINILIFDGCP 231 4689*******************876653 PP >> LRR_Zer-1 Zer-1-like, Leucine-rich repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 1.9 5.5e+03 64 86 .. 23 45 .. 10 53 .. 0.75 2 ! 10.8 0.2 0.0002 0.57 24 68 .. 55 99 .. 39 110 .. 0.85 3 ! 9.6 0.2 0.00046 1.3 75 108 .. 156 189 .. 150 209 .. 0.82 4 ? -1.6 0.0 1.3 3.8e+03 10 56 .. 196 250 .. 191 251 .. 0.50 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.9 LRR_Zer-1 64 seeetgvykkpvtvLkklvesLp 86 ++et+ y pv++ +kl++ L+ FUN_000544-T1 23 PKHETSLYALPVEIKAKLIHLLS 45 56788888888888888888776 PP == domain 2 score: 10.8 bits; conditional E-value: 0.0002 LRR_Zer-1 24 lellskesLtsLiLydvkdleeaidticqlkkLrhLDisqseeet 68 +e + + sL++L L +++ ++ + ++c k+Lr+LD+ +++++ FUN_000544-T1 55 IEKVLHPSLRDLELCECRISDSGLASLCVCKNLRKLDLNATKNSR 99 45556789******************************9988764 PP == domain 3 score: 9.6 bits; conditional E-value: 0.00046 LRR_Zer-1 75 vtvLkklvesLpkLtsLDiSgtnLagkpsaedrp 108 t L+ l ++ + L+sL iS+t +++++ + ++ FUN_000544-T1 156 DTSLHVLAKNCKFLQSLNISKTKVTDNGIMQLTT 189 689**********************999765444 PP == domain 4 score: -1.6 bits; conditional E-value: 1.3 LRR_Zer-1 10 Lttldlsewskledlellsk....esLtsLiLydvkdle....eaidticqlkkL 56 ++ + +s++ +++d ++ +++ Li ++++ +ai++ qlk+L FUN_000544-T1 196 IKEVQVSHCIHITDASIEALlalcPRINILIFDGCPHVTessrHAIEEAGQLKQL 250 5566667776666654332201124566666666665441111455555666655 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.011 33 1 21 [. 62 82 .. 62 84 .. 0.87 2 ? 2.0 0.0 0.23 6.4e+02 1 13 [. 86 98 .. 86 106 .. 0.78 3 ? -0.3 0.0 1.3 3.7e+03 2 11 .. 117 126 .. 116 137 .. 0.78 4 ? 4.9 0.2 0.023 66 1 12 [. 142 153 .. 142 165 .. 0.77 5 ? 1.8 0.0 0.26 7.4e+02 2 14 .. 169 181 .. 168 188 .. 0.80 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.011 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L+ L L+ +++s++ + sl+ FUN_000544-T1 62 SLRDLELCECRISDSGLASLC 82 799*********999888887 PP == domain 2 score: 2.0 bits; conditional E-value: 0.23 LRR_1 1 nLeeLdLsnNnls 13 nL++LdL+ ++ s FUN_000544-T1 86 NLRKLDLNATKNS 98 8******877764 PP == domain 3 score: -0.3 bits; conditional E-value: 1.3 LRR_1 2 LeeLdLsnNn 11 L++++L+++ FUN_000544-T1 117 LQTVYLRRCI 126 8999999985 PP == domain 4 score: 4.9 bits; conditional E-value: 0.023 LRR_1 1 nLeeLdLsnNnl 12 +Le+L+L+++ FUN_000544-T1 142 HLEHLNLCGCIN 153 79********76 PP == domain 5 score: 1.8 bits; conditional E-value: 0.26 LRR_1 2 LeeLdLsnNnlsg 14 L++L++s ++ ++ FUN_000544-T1 169 LQSLNISKTKVTD 181 99*****998864 PP >> DNA_pol_A_exo1 3'-5' exonuclease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 7e-05 0.2 32 91 .. 10 69 .. 7 89 .. 0.87 2 ? -0.3 0.0 0.39 1.1e+03 117 141 .. 154 183 .. 102 198 .. 0.62 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 7e-05 DNA_pol_A_exo1 32 ldlisarlrlaliqiseeeeayiidpleleddalealke..lledpnitkvfhnakfDlevl 91 l+ + lr++ +q+ ++e + p+e++++ +++l++ ll+d+ni+kv+h Dle + FUN_000544-T1 10 LQN--HCLRAVACQLPKHETSLYALPVEIKAKLIHLLSKrgLLTDSNIEKVLHPSLRDLELC 69 555..7789999******999999********999996555************999999866 PP == domain 2 score: -0.3 bits; conditional E-value: 0.39 DNA_pol_A_exo1 117 s..hsLadLaek..llg.veldkeeqasdw 141 sL La++ +l+ ++++k+++++++ FUN_000544-T1 154 ItdTSLHVLAKNckFLQsLNISKTKVTDNG 183 133566666653224556777777666665 PP >> PRANC PRANC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.0003 0.86 62 90 .. 18 47 .. 7 51 .. 0.78 2 ? 0.3 0.2 0.45 1.3e+03 6 66 .. 78 140 .. 73 149 .. 0.65 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.0003 PRANC 62 lneicsk.kslWnlLPiEikykIleyLsdk 90 + + + k +++++ LP+Eik k + Ls+ FUN_000544-T1 18 VACQLPKhETSLYALPVEIKAKLIHLLSKR 47 5555555799***************99976 PP == domain 2 score: 0.3 bits; conditional E-value: 0.45 PRANC 6 lydilfnknninllvrlvnnkklkklk..slkiYgklikkiiksakerykliekalevlneic 66 l ++++kn ++l + +n + + ++ +k++ ++ + ++++ + + a+ +l+e+c FUN_000544-T1 78 LASLCVCKNLRKLDLNATKNSRDDITSegVIKVFTSCCQLQTVYLRRCINVSDTAIITLTENC 140 677889999988888888888877666555677766666555555555555555555555555 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.1 0.0043 12 25 57 .. 61 93 .. 60 97 .. 0.56 2 ? 3.9 0.6 0.022 63 1 37 [. 141 179 .. 141 181 .. 0.82 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0043 LRR_8 25 snLkvLdLsnNllttlspgafsgLpsLrsLdLs 57 ++L+ L L + +++ ++ +++Lr+LdL+ FUN_000544-T1 61 PSLRDLELCECRISDSGLASLCVCKNLRKLDLN 93 455555555555555555555556666666655 PP == domain 2 score: 3.9 bits; conditional E-value: 0.022 LRR_8 1 pnLrsLdLssNr.ltslddgaFkg.lsnLkvLdLsnNll 37 ++L+ L+L+ +t+ + ++ + ++ L++L++s+ + FUN_000544-T1 141 RHLEHLNLCGCInITDTSLHVLAKnCKFLQSLNISKTKV 179 689999999988899999888877699999999998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (255 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 941 (0.036837); expected 510.9 (0.02) Passed bias filter: 499 (0.0195342); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2556.33 // Query: FUN_000545-T1 [L=328] Description: FUN_000545 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-23 82.4 0.1 6.5e-23 82.0 0.1 1.1 1 DeoC DeoC/LacD family aldolase ------ inclusion threshold ------ 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 MscS_porin Mechanosensitive ion channel porin domain 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 DHO_dh Dihydroorotate dehydrogenase Domain annotation for each model (and alignments): >> DeoC DeoC/LacD family aldolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.0 0.1 7.7e-27 6.5e-23 4 216 .. 62 287 .. 59 307 .. 0.89 Alignments for each domain: == domain 1 score: 82.0 bits; conditional E-value: 7.7e-27 DeoC 4 lavDqgvangpdtasaledlkalvkeaaep................ganavlldkgviasvsreygk......diglivklnsgtdlvpskqrdvl 77 +D++++ g+dta +++ l+ +a +p ++av+++ +++++ ++++ +++++ +++g++ ++++ FUN_000545-T1 62 TCIDLTTLSGDDTAT---NVARLCFKAQNPvrqdllesmgmadrglTTGAVCVYSSRVPDAVKTLKDiqskvpVASVAAGFPAGQTPIKQR----- 149 679************...99999999999999999999****************************9999776667788999999999999..... PP DeoC 78 evasveeaialGAdaVkvvvyvavdgseeeqqklqeikrvkeaChelgmplile.iylrgeaikdekdpdlvakAaklgaelGaDivKvevpkegv 172 ++++e a+a GA+++++v+++a ++q ++e+k++++aC+e+++++i++ ++l + +v+kA+ + +G+D++K++++ke+v FUN_000545-T1 150 -LEEIETAVASGATEIDIVISRAFVLEAKWQALYDEVKAMRKACGEAHLKTIIAtGELGSLS--------NVYKASLVCMMAGSDFIKTSTGKESV 236 .9********************9999999*************************99999999........************************** PP DeoC 173 nageedaevfkevikaapvp......vvlaGGv.seedfletvrdavkeag 216 na+ v+ +++++ + +++aGG+ s++d l + ++e g FUN_000545-T1 237 NATLPVGLVMVRAVRDYYQQtghkvgFKPAGGIrSAKDALTWLALMKEELG 287 **************998777888899*******999887766655444555 PP >> MscS_porin Mechanosensitive ion channel porin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.5e-05 0.12 117 169 .. 138 189 .. 114 193 .. 0.87 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.5e-05 MscS_porin 117 raqqqlteakqrlqeienqLnalaasge.alseaqrvalqaeqaalkaqiemle 169 +++ +t kqrl+eie+ +++ + e ++ ++ + l+a+++al ++++ + FUN_000545-T1 138 GFPAGQTPIKQRLEEIETAVASG--ATEiDIVISRAFVLEAKWQALYDEVKAMR 189 67788999**********99999..6667******************9998665 PP >> DHO_dh Dihydroorotate dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 2.9e-05 0.25 211 257 .. 228 277 .. 180 280 .. 0.66 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 2.9e-05 DHO_dh 211 anktGGlsGkaikpia...lkvirelyerlkkeipiIgvGGiesgeDale 257 + tG s +a p++ ++ +r+ y+++++++ GGi s++Dal FUN_000545-T1 228 KTSTGKESVNATLPVGlvmVRAVRDYYQQTGHKVGFKPAGGIRSAKDALT 277 5555555555555555111566777899999999999***********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (328 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 708 (0.0277158); expected 510.9 (0.02) Passed bias filter: 618 (0.0241926); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 3166.84 // Query: FUN_000546-T1 [L=106] Description: FUN_000546 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (106 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 491 (0.019221); expected 510.9 (0.02) Passed bias filter: 388 (0.0151889); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1061.38 // Query: FUN_000547-T1 [L=300] Description: FUN_000547 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-32 111.5 8.5 2.5e-19 69.3 2.0 3.6 4 PQ-loop PQ loop repeat ------ inclusion threshold ------ 0.015 15.7 1.4 1.5 9.1 0.6 2.4 2 DUF3611 Protein of unknown function (DUF3611) 0.19 11.9 1.3 1.3 9.3 0.3 2.5 2 DUF6768 Family of unknown function (DUF6768) 1 9.8 4.7 1.4 9.3 0.0 2.2 2 DUF1673 Protein of unknown function (DUF1673) 9.9 6.8 6.9 1.6e+02 2.9 0.0 3.7 4 HemY_N HemY protein N-terminus Domain annotation for each model (and alignments): >> PQ-loop PQ loop repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.3 2.0 4.9e-23 2.5e-19 2 58 .. 11 67 .. 10 70 .. 0.94 2 ? -1.3 0.5 0.52 2.6e+03 40 52 .. 88 100 .. 86 105 .. 0.50 3 ? -2.8 0.9 1.5 7.7e+03 39 56 .. 118 135 .. 115 143 .. 0.69 4 ! 53.5 0.5 4.1e-18 2.1e-14 3 52 .. 147 196 .. 145 205 .. 0.95 Alignments for each domain: == domain 1 score: 69.3 bits; conditional E-value: 4.9e-23 PQ-loop 2 snilgyislvlwlisyiPQiikNykrkSteGlSilflllwllGgilsllylilnsfp 58 + ++g+ ++++w +s++PQi++N++rk+++G+S+++l ll++i++l+y+++ f FUN_000547-T1 11 ADLVGWGYFFCWTVSFLPQIYENWRRKCVVGFSFDMLGYFLLSYITYLIYNVTVFFK 67 6789************************************************98776 PP == domain 2 score: -1.3 bits; conditional E-value: 0.52 PQ-loop 40 lwllGgilsllyl 52 ++++++i+ +++ FUN_000547-T1 88 FAIVAFICTVFQA 100 3444444444444 PP == domain 3 score: -2.8 bits; conditional E-value: 1.5 PQ-loop 39 llwllGgilsllylilns 56 +l+++G+++ ++ l++ + FUN_000547-T1 118 VLACVGCLFGFAVLVILK 135 677778777777666655 PP == domain 4 score: 53.5 bits; conditional E-value: 4.1e-18 PQ-loop 3 nilgyislvlwlisyiPQiikNykrkSteGlSilflllwllGgilsllyl 52 +++gy++lv+++ y PQ+++N+krkSt G+ i +ll++ Gg+ls+l++ FUN_000547-T1 147 QYCGYVKLVVSFGTYSPQVWLNFKRKSTSGFHIGGVLLDFGGGVLSILQM 196 79*********************************************997 PP >> DUF3611 Protein of unknown function (DUF3611) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.6 0.0003 1.5 35 79 .. 62 113 .. 28 140 .. 0.75 2 ? 5.2 0.0 0.0048 24 26 72 .. 189 233 .. 163 264 .. 0.70 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0003 DUF3611 35 fallsrsl.......esnaglgfglflavlglvlllfsiywafrytrlarrl 79 ++++++ e n+ +++a++++++ +f + +f y r ++r+ FUN_000547-T1 62 VTVFFKPElvfeksgEDNPVKLTDVVFAIVAFICTVFQAIQCFVYDRGSQRI 113 4444443345554456666667778999999999999999999999999988 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0048 DUF3611 26 gvvsalillfallsrslesnaglgfglflavlglvlllfsiywafry 72 gv+s+l + + ++ +++ n++++ + +lglv+llf i++ ++ FUN_000547-T1 189 GVLSILQMDIYCFIEHS--NTQITGNIPKLALGLVTLLFDIILVWQH 233 77788888888888875..9999999999999******999887763 PP >> DUF6768 Family of unknown function (DUF6768) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.3 0.00025 1.3 47 90 .. 85 133 .. 74 141 .. 0.73 2 ? 0.6 0.0 0.12 5.9e+02 58 90 .. 197 229 .. 190 248 .. 0.70 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00025 DUF6768 47 vnivqivffvlfvycavqffqaeevnelikWg.....vgalvlllvvam 90 +++ iv+f+++v+ a+q f + + i+++ vg+l+ + v + FUN_000547-T1 85 DVVFAIVAFICTVFQAIQCFVYDRGSQRIHFStvlacVGCLFGFAVLVI 133 57899************************99822111234444444444 PP == domain 2 score: 0.6 bits; conditional E-value: 0.12 DUF6768 58 fvycavqffqaeevnelikWgvgalvlllvvam 90 +yc+++ +++ + + k ++g ++ll+ +++ FUN_000547-T1 197 DIYCFIEHSNTQITGNIPKLALGLVTLLFDIIL 229 578888888888888887777777776654444 PP >> DUF1673 Protein of unknown function (DUF1673) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 2.0 0.097 4.9e+02 91 175 .. 50 137 .. 13 145 .. 0.54 2 ? 9.3 0.0 0.00028 1.4 80 128 .. 212 262 .. 190 276 .. 0.84 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.097 DUF1673 91 sllllIllwkkqlqlydknslaekpvikisvKkklfllflvilavillllilllyvesiagelqleevlssfiag...llllvwlvyl 175 ll +I ++ + + k++l+ +++ + k+ ++f+++ + ++ +++ +v ++ + + +++++ ++ + +lv+l y+ FUN_000547-T1 50 FLLSYITYLIYNVTVFFKPELVFEKSGEDNPVKLTDVVFAIVAFICTVFQAIQCFVYDRGSQRIHFSTVLACVGClfgFAVLVILKYF 137 4455555555555555567777666666555555554554444444444444444433333322222222222221124555555565 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00028 DUF1673 80 nlialiigllisllllIllwkkqlqlyd..knslaekpvikisvKkklfll 128 n+ l +gl+ +l+ +Il w+ ++ ++ + s ekp + s K+k+++l FUN_000547-T1 212 NIPKLALGLVTLLFDIILVWQHYVFYLGneQVSEEEKPLLSGSKKEKIYSL 262 7778899**************999888887788889999999999999855 PP >> HemY_N HemY protein N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.038 2e+02 14 49 .. 1 36 [. 1 38 [. 0.91 2 ? -1.7 0.1 0.87 4.4e+03 15 28 .. 85 98 .. 83 105 .. 0.73 3 ? 2.7 0.4 0.038 1.9e+02 8 36 .. 109 137 .. 104 148 .. 0.84 4 ? 2.9 0.0 0.031 1.6e+02 4 41 .. 201 238 .. 199 247 .. 0.86 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.038 HemY_N 14 tslvvavlllvllfvllylllrllrlllrlprrvrr 49 +s ++++ +l+ l+ y++ +++++l ++ +++rr FUN_000547-T1 1 MSSTTFLTVLADLVGWGYFFCWTVSFLPQIYENWRR 36 788999999******************999999887 PP == domain 2 score: -1.7 bits; conditional E-value: 0.87 HemY_N 15 slvvavlllvllfv 28 +v+a+++++++++ FUN_000547-T1 85 DVVFAIVAFICTVF 98 57888888888876 PP == domain 3 score: 2.7 bits; conditional E-value: 0.038 HemY_N 8 ggyrietslvvavlllvllfvllylllrl 36 g+ ri s v+a + ++ f++l++l ++ FUN_000547-T1 109 GSQRIHFSTVLACVGCLFGFAVLVILKYF 137 578999*****************999766 PP == domain 4 score: 2.9 bits; conditional E-value: 0.031 HemY_N 4 lislggyrietslvvavlllvllfvllylllrllrlll 41 i+ +++i+ +++ ++l lv l++ ++l+++ + l FUN_000547-T1 201 FIEHSNTQITGNIPKLALGLVTLLFDIILVWQHYVFYL 238 6888999************************9776655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (300 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1053 (0.0412214); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2962.72 // Query: FUN_000548-T1 [L=201] Description: FUN_000548 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 777 (0.0304169); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1973.75 // Query: FUN_000549-T1 [L=220] Description: FUN_000549 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-15 56.3 0.0 4.5e-15 56.0 0.0 1.1 1 UQ_con Ubiquitin-conjugating enzyme Domain annotation for each model (and alignments): >> UQ_con Ubiquitin-conjugating enzyme # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.0 0.0 1.8e-19 4.5e-15 3 137 .. 17 150 .. 15 153 .. 0.93 Alignments for each domain: == domain 1 score: 56.0 bits; conditional E-value: 1.8e-19 UQ_con 3 qkelkelkkkppsgisakpvddenllewkvtilgpedtpYeggvFklelefpedYPfkpPkvkfttkiyHPnvd.esGevcldiLkeekWsp.alt 96 ++el +l++++ +g++a p+ + +l+ w+++i+ +++pY++g+F++ + ++++ P + P +kft++++HP vd +sG + l + W + FUN_000549-T1 17 MNELCHLAQNHLKGVYAMPSLK-SLNVWHGIIFV-RGGPYQNGIFRFVIFLQHESPGSQPVLKFTSPLFHPQVDpKSGILNLGVKF-PPWDRsKNK 109 67888999*************7.***********.***************************************999999999955.459886899 PP UQ_con 97 lesvllsiqsLlsepnpesplnaeaaklykknreefekkvk 137 + ++l + s + + ++ ++n+ a + +++n eef++++ FUN_000549-T1 110 IFQILKFMKSCFYNVQTWGGANKVAINVIHRNIEEFKHRAA 150 *************************************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (220 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 488 (0.0191035); expected 510.9 (0.02) Passed bias filter: 422 (0.0165199); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2164.93 // Query: FUN_000550-T1 [L=338] Description: FUN_000550 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.7e-31 107.7 14.7 3.5e-30 105.8 14.7 1.8 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.00017 22.0 9.9 0.0023 18.3 0.2 2.9 3 7tm_4 Olfactory receptor Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.8 14.7 2.7e-34 3.5e-30 2 260 .] 25 269 .. 24 269 .. 0.90 Alignments for each domain: == domain 1 score: 105.8 bits; conditional E-value: 2.7e-34 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrir 97 N+lV+ ++++ k++r+ tn f+++La++D+l++ + f l y+l g+w ++++al+ + l+++ +l+a+++DRYlaI +p+ y ri FUN_000550-T1 25 NTLVCGLVFKVKSMRNYTNGFVVSLAISDILTG---TAFLLQYNLNLGRWSQ-----AALNALYAIVLFVGASNLCAVTYDRYLAILHPFAYARI- 111 9********************************...7778888886566665.....4569*******************************765. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.... RF 7tm_1 98 tkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.... 189 kr ++l+ ++W++++ ++++p+ + + + +i +p+ ++y+ ++v++ lp+++i++ +++il +r+s ++e++ FUN_000550-T1 112 IKRAFKILVPGIWLISIGIACIPFAWFEDN-----------TIGLPS------QIYNCSVLVICIALPFVLIVYANFKILLLVRRSVRRERQlsvs 190 56999******************8844333...........466777......6899999******************************999999 PP ...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ...........kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + ++++++e+k++++ ++ ++f+l ++P++ + +++ +++ +++ +++++ +++++ s++NPi+Y FUN_000550-T1 191 sgpsdktnskrNGTRKVSSEAKVARVFAIASFMFALSYFPMLYYTAAMTF---HHRDATPKLMTQLSPFCIVFGSLVNPILY 269 999999888775555566777*****************************...99999999999*****************9 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 1.0 0.00012 1.5 77 109 .. 83 115 .. 11 139 .. 0.73 2 ? -1.2 0.1 0.16 2e+03 166 197 .. 148 179 .. 139 194 .. 0.66 3 ! 18.3 0.2 1.8e-07 0.0023 209 280 .] 210 287 .. 198 287 .. 0.75 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.00012 7tm_4 77 fsllesavllamavdrfvaiysplryteiltnk 109 + ++ ++ l a+++dr+ ai +p+ y+ i FUN_000550-T1 83 VLFVGASNLCAVTYDRYLAILHPFAYARIIKRA 115 3456678899******************98665 PP == domain 2 score: -1.2 bits; conditional E-value: 0.16 7tm_4 166 niyGlfvvvstlgldsllivlsyglilrtvlg 197 +iy v+v ++l +liv + +il v + FUN_000550-T1 148 QIYNCSVLVICIALPFVLIVYANFKILLLVRR 179 56777777777777777777777777765544 PP == domain 3 score: 18.3 bits; conditional E-value: 1.8e-07 7tm_4 209 ntcgshvcavlaf.....yvPmiglsvvhrfgkk.vsrllqvllanlyllfPPvlnPivysvktkeirdavvkillek 280 ++ ++ v+a+ f y Pm++ + f ++ ++ l + l+ ++f ++nPi+ys + r+av+kil+ k FUN_000550-T1 210 EAKVARVFAIASFmfalsYFPMLYYTAAMTFHHRdATPKLMTQLSPFCIVFGSLVNPILYSFMKPDFRRAVKKILSAK 287 44455555554443344489***9988888876535677778889999**************************9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (338 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1137 (0.0445097); expected 510.9 (0.02) Passed bias filter: 652 (0.0255236); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3307.18 // Query: FUN_000551-T1 [L=89] Description: FUN_000551 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.043 14.3 0.3 0.075 13.6 0.0 1.5 2 HAT_PRP39_C PRP39 C-terminal HAT repeat Domain annotation for each model (and alignments): >> HAT_PRP39_C PRP39 C-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.1 0.24 6.1e+03 18 29 .. 10 21 .. 9 23 .. 0.80 2 ? 13.6 0.0 2.9e-06 0.075 55 87 .. 45 77 .. 40 86 .. 0.85 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.24 HAT_PRP39_C 18 kpleeaqlknWr 29 +p + +qlk W+ FUN_000551-T1 10 NPSDLQQLKRWS 21 577889999996 PP == domain 2 score: 13.6 bits; conditional E-value: 2.9e-06 HAT_PRP39_C 55 calyeefWlrYaryleskseeearnvyeracti 87 ye++W Y++ le+k+++ +r++ ra t FUN_000551-T1 45 GHKYENVWNDYTKALERKEIDGVRQLTLRAETH 77 578**************************9653 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (89 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 577 (0.0225876); expected 510.9 (0.02) Passed bias filter: 425 (0.0166373); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 914.06 // Query: FUN_000552-T1 [L=213] Description: FUN_000552 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-21 74.5 0.1 4.7e-20 72.2 0.0 2.1 3 BTB_2 BTB/POZ domain 3.4e-05 24.2 0.0 5.6e-05 23.5 0.0 1.3 1 BTB_3 BTB/POZ domain Domain annotation for each model (and alignments): >> BTB_2 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.2 0.0 3.6e-24 4.7e-20 1 92 [. 21 110 .. 21 112 .. 0.91 2 ? -1.3 0.0 0.31 4e+03 46 63 .. 131 148 .. 123 155 .. 0.80 3 ? -2.6 0.0 0.79 1e+04 20 48 .. 185 211 .. 175 213 .] 0.52 Alignments for each domain: == domain 1 score: 72.2 bits; conditional E-value: 3.6e-24 BTB_2 1 vklnVgGtrfetskstLtrkpdtlLkklleteeldaydeetneyffDRspklFetiLnflrtg.gkLhepeevelkelleElefygleelale 92 v lnVgG + ts + Ltr+p+++L+ +++ + +++++++f+DR+ +F+++Lnflr+ +L+++ +e ++l+eE++fy++++l +e FUN_000552-T1 21 VDLNVGGCLYTTSLDSLTRYPNSMLGIMFSGR-RWIAKDSRGRFFIDRDGPMFRYVLNFLRSSkLNLPDN-FQEFDQLMEEADFYQISQL-IE 110 78****************************88.88889999*********************66666666.6899*************99.55 PP == domain 2 score: -1.3 bits; conditional E-value: 0.31 BTB_2 46 fDRspklFetiLnflrtg 63 +DR+++ et+L+ + ++ FUN_000552-T1 131 LDRDKHGLETLLTIYAEK 148 799999999999999874 PP == domain 3 score: -2.6 bits; conditional E-value: 0.79 BTB_2 20 kpdtlLkklleteeldaydeetneyffDR 48 ++ ++ +++ + + d++ ne ff R FUN_000552-T1 185 LTNHGFQVMTSLS--HPGDQSINEWFFIR 211 4444455555544..44455556666655 PP >> BTB_3 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 4.4e-09 5.6e-05 4 95 .. 23 110 .. 20 120 .. 0.85 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 4.4e-09 BTB_3 4 lvvdetrfvvdkslftahPdtmlgrmfssslernltkpnekGeyevaegissevfraildyyktGvikcPpsv.sikelreacdyllipfdak 95 l v ++ ++ +t++P++mlg mfs r ++ ++ +G + +++ +fr +l++ ++ +++ P+ ++l e d++ i+ + FUN_000552-T1 23 LNVGGCLYTTSLDSLTRYPNSMLGIMFSG---RRWIAKDSRGRFFIDRD--GPMFRYVLNFLRSSKLNLPDNFqEFDQLMEEADFYQISQLIE 110 557777777888899************98...678999********996..789****************98625889999999999976555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (213 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 574 (0.0224702); expected 510.9 (0.02) Passed bias filter: 515 (0.0201605); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2087.86 // Query: FUN_000553-T1 [L=220] Description: FUN_000553 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-18 65.9 0.0 8.7e-18 65.0 0.0 1.4 1 BTB_2 BTB/POZ domain Domain annotation for each model (and alignments): >> BTB_2 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.0 0.0 3.4e-22 8.7e-18 1 89 [. 9 94 .. 9 98 .. 0.89 Alignments for each domain: == domain 1 score: 65.0 bits; conditional E-value: 3.4e-22 BTB_2 1 vklnVgGtrfetskstLtrkpdtlLkklleteeldaydeetneyffDRspklFetiLnflrtg.gkLhepeevelkelleElefygleel 89 v lnVgG+ + t+ t+t++pd+ L++l+++ + ++ ++++f+DR+ +lF+++Lnflr+g L+++ +e ++l+ E+ +y++++l FUN_000553-T1 9 VGLNVGGVLYTTTLYTITQFPDSKLAELFDA---KIPKDPKGNFFIDRDGHLFKYVLNFLRSGkLVLPKN-FQEYEQLEIEAMYYHIKPL 94 679***************************4...5889999*********************54445554.578999**********976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (220 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 537 (0.0210217); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2200.75 // Query: FUN_000554-T1 [L=227] Description: FUN_000554 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.26 11.0 0.1 0.44 10.3 0.1 1.3 1 DUF3959 Protein of unknown function (DUF3959) Domain annotation for each model (and alignments): >> DUF3959 Protein of unknown function (DUF3959) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.1 1.7e-05 0.44 151 182 .. 195 226 .. 187 227 .] 0.93 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 1.7e-05 DUF3959 151 nrengngkqkspsgfeqkkkrmrptfkirlpr 182 re g gk+k + ++kkk ++ + irlp+ FUN_000554-T1 195 RREAGSGKHKRDTYCDDKKKTLKKYIEIRLPK 226 69*****************************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (227 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 960 (0.0375807); expected 510.9 (0.02) Passed bias filter: 507 (0.0198473); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2279.14 // Query: FUN_000555-T1 [L=177] Description: FUN_000555 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (177 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1163 (0.0455275); expected 510.9 (0.02) Passed bias filter: 598 (0.0234097); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1737.56 // Query: FUN_000556-T1 [L=332] Description: FUN_000556 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-35 122.2 20.5 3.9e-22 79.5 7.8 2.1 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.8e-08 34.6 13.8 2.5e-07 30.8 4.1 2.4 2 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.23 11.9 0.3 0.41 11.1 0.3 1.4 1 FtsL_2 Bacteriodetes cell division protein (FtsL-like 2.5 7.5 7.6 26 4.2 7.6 2.3 1 Pex24p Integral peroxisomal membrane peroxin 9 7.0 9.6 2.4 8.9 2.5 2.6 2 DUF6097 Family of unknown function (DUF6097) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.5 7.8 7.7e-26 3.9e-22 1 122 [. 39 163 .. 39 169 .. 0.88 2 ! 48.5 5.2 2.1e-16 1.1e-12 153 260 .] 169 284 .. 166 284 .. 0.85 Alignments for each domain: == domain 1 score: 79.5 bits; conditional E-value: 7.7e-26 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgev.lCklvtaldvvnltasillltaisiDRYlaIvkplky 93 gNllV+l+++ nk lr+p +++ nLa+aDl+v++++ p++ vy++ + + + l v++ +++++tas+l+l+a++iDRYlaI+ p++y FUN_000556-T1 39 GNLLVVLAVFIdpNKDLRSPFMYLVANLALADLVVGVVTDPVSSVYHFKSALGLINNGtLILSVHMPFFISCTASVLSLAALTIDRYLAITSPIRY 134 8999999999878899******************************9944444443331456788899**************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppll 122 ++ ++ ra++ +++vW+l+l + + l+ FUN_000556-T1 135 RTTLNPMRAILACVLVWILSLSFPFAYLY 163 ********************988777665 PP == domain 2 score: 48.5 bits; conditional E-value: 2.1e-16 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 153 ytlllsvlgfllpllvilvcyvrilrtlrksakkeks.........kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklve 239 yt+l+ +++l + ++l+ y+ri++t r++ ++ ++ +k +r e+k++ktll+++++f+ c+lP ++ + l ++++s++l+ FUN_000556-T1 169 YTFLFANTAVVLTFAILLIAYIRIYKTFRRQVREWDKlhdsteenrARKLTVRWEQKITKTLLIMLALFISCYLPACAFIYVINL-CNTCSCDLIL 263 44445555567799*********************997777666665556666666**********************9999999.6777888999 PP xxxxxxxxxxxxxxxxxxxxx RF 7tm_1 240 tallitlllayvnsclNPiiY 260 +a ++ ll+++ns +NP+iY FUN_000556-T1 264 WARDLQFLLILANSSMNPFIY 284 9******************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.8 4.1 5e-11 2.5e-07 3 119 .. 35 157 .. 33 170 .. 0.73 2 ! 8.0 3.3 0.00047 2.4 151 253 .. 169 295 .. 163 298 .. 0.68 Alignments for each domain: == domain 1 score: 30.8 bits; conditional E-value: 5e-11 7TM_GPCR_Srsx 3 vGliGNvllilltfk..kkkLrskssiLicvqcladllc.lvgelvfvvllltgt.qlkreeCFlliivy.vfgltaqsvllL.vigiDlliavkf 92 v + GN+l++l++f +k Lrs++ +L+ ++ladl++ +v v+ v ++ l + +l++++ f +++svl L +++iD+ +a++ FUN_000556-T1 35 VTIPGNLLVVLAVFIdpNKDLRSPFMYLVANLALADLVVgVVTDPVSSVYHFKSAlGLINNGTLILSVHMpFFISCTASVLSLaALTIDRYLAITS 130 7788********99844689*****************98344555666677765414445555555554404556788888883599********* PP 7TM_GPCR_Srsx 93 PirYrllskekYllillifpvlyssii 119 PirYr+ + ++ ++++ + s+++ FUN_000556-T1 131 PIRYRTTLNPMRAILACVLVWILSLSF 157 *******99998888888887777654 PP == domain 2 score: 8.0 bits; conditional E-value: 0.00047 7TM_GPCR_Srsx 151 lssliinvivllvylvliiilkkkkek.......................kkssskkvlkslkvtvvififgWftstilntvllalteseevekli 223 ++ l+ n++v+l +++l i + + ++ + + +k+ k l +++ +fi + + + ++ v+ + + l FUN_000556-T1 169 YTFLFANTAVVLTFAILLIAYIRIYKTfrrqvrewdklhdsteenrarklTVRWEQKITKTLLIMLALFISCYLPACAFIYVINLCNTCSCDLILW 264 55555555555555555544333333334445669999*****9999999999999**************99887666555554444333333344 PP 7TM_GPCR_Srsx 224 qay.agilvllsfsqnffVtywrsseYrkaf 253 ++l+l ++s n f++ wr ++ r+af FUN_000556-T1 265 ARDlQFLLILANSSMNPFIYSWRLRDCRRAF 295 444145566778889*********9999998 PP >> FtsL_2 Bacteriodetes cell division protein (FtsL-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.3 8.1e-05 0.41 8 64 .. 166 222 .. 159 230 .. 0.86 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8.1e-05 FtsL_2 8 flvsedavknwrfilFlvlLallmIanshsaekkvreiaklnkevkelrseyvdlks 64 f+ + + n ++l +++L++ +I ++ ++vre +kl++ ++e r++ ++++ FUN_000556-T1 166 FIHYTFLFANTAVVLTFAILLIAYIRIYKTFRRQVREWDKLHDSTEENRARKLTVRW 222 55556788999999*9********************************999888775 PP >> Pex24p Integral peroxisomal membrane peroxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 7.6 0.0052 26 44 105 .. 155 225 .. 149 329 .. 0.81 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0052 Pex24p 44 lsfllvytficlvpylelvvlpllpllfvvmvpgylyrhsplpkssl......edknestaekptld...e 105 lsf + y+++ ++ y l++ +++l f++++++y++++++ +++++ ++++e+ a+k t++ + FUN_000556-T1 155 LSFPFAYLYLGFIHYTFLFANTAVVLTFAILLIAYIRIYKTFRRQVRewdklhDSTEENRARKLTVRweqK 225 799999**************************************999665554333333333333335553 PP >> DUF6097 Family of unknown function (DUF6097) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 2.5 0.00046 2.4 104 143 .. 169 207 .. 120 224 .. 0.72 2 ? 1.9 0.6 0.065 3.3e+02 61 107 .. 225 274 .. 218 303 .. 0.70 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00046 DUF6097 104 fefllenlpvviilaavllgvilyfyvlnskleeelekli 143 fl+ n +vv ++a++l++ i +++ ++++++ e kl FUN_000556-T1 169 YTFLFANTAVVLTFAILLIAYIRIYKTFRRQVR-EWDKLH 207 568899999**********************99.444444 PP == domain 2 score: 1.9 bits; conditional E-value: 0.065 DUF6097 61 kkvnilsgvlAlpv...llfalllflisklskldvdlklaeisqalfefl 107 k+++ l+++lAl + l +++++++i+ +++ + dl l++ + + l FUN_000556-T1 225 KITKTLLIMLALFIscyLPACAFIYVINLCNTCSCDLILWARDLQFLLIL 274 56677777888877444567999*******99999988887655444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1444 (0.0565277); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3261.03 // Query: FUN_000557-T1 [L=89] Description: FUN_000557 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (89 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 743 (0.0290859); expected 510.9 (0.02) Passed bias filter: 483 (0.0189078); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 891.92 // Query: FUN_000558-T1 [L=203] Description: FUN_000558 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1706 (0.0667841); expected 510.9 (0.02) Passed bias filter: 550 (0.0215306); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2023.49 // Query: FUN_000559-T1 [L=538] Description: FUN_000559 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.1e-125 407.4 80.0 2.1e-19 70.1 3.5 7.5 7 HS1_rep Repeat in HS1/Cortactin 3.8e-18 65.3 0.2 9.4e-18 64.0 0.2 1.7 1 SH3_1 SH3 domain 1.1e-16 60.8 0.1 2.9e-16 59.5 0.1 1.8 1 SH3_9 Variant SH3 domain 2.2e-09 37.3 1.3 7.6e-09 35.6 0.0 2.6 3 SH3_2 Variant SH3 domain 2.5e-09 38.1 5.1 5.2 8.1 0.0 7.0 7 TMEM210 TMEM210 family 0.0011 19.1 40.2 0.71 10.1 0.5 7.3 7 CjCas9_WED-like CRISPR-associated endonuclease CjCas9 wedge 0.0022 19.3 5.8 55 5.2 0.1 6.0 7 Endonuc_subdom PI-PfuI Endonuclease subdomain ------ inclusion threshold ------ 0.28 11.3 2.9 1.3e+02 2.8 0.0 4.3 5 zf-CCHC_4 Zinc knuckle Domain annotation for each model (and alignments): >> HS1_rep Repeat in HS1/Cortactin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.1 5.8 1.2e-21 3.7e-18 1 36 [] 81 116 .. 81 116 .. 0.99 2 ! 69.3 6.4 1.2e-22 3.9e-19 1 36 [] 118 153 .. 118 153 .. 0.99 3 ! 69.6 4.8 9.7e-23 3.1e-19 1 36 [] 155 190 .. 155 190 .. 0.99 4 ! 67.3 3.9 4.9e-22 1.6e-18 1 36 [] 192 227 .. 192 227 .. 0.99 5 ! 68.1 6.3 2.8e-22 8.9e-19 1 36 [] 229 264 .. 229 264 .. 0.99 6 ! 70.1 3.5 6.6e-23 2.1e-19 1 36 [] 266 301 .. 266 301 .. 0.99 7 ! 34.4 2.0 9.4e-12 3e-08 1 27 [. 303 329 .. 303 330 .. 0.95 Alignments for each domain: == domain 1 score: 66.1 bits; conditional E-value: 1.2e-21 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekvekHeSQkDys 36 G+GGKFGVqkDr Dk vGwdy++kv+kH+SQkDy+ FUN_000559-T1 81 GYGGKFGVQKDRIDKNVVGWDYEGKVDKHASQKDYA 116 9**********************************6 PP == domain 2 score: 69.3 bits; conditional E-value: 1.2e-22 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekvekHeSQkDys 36 GFGGK+GVqkDrvD++AvG++y++k+ekHeSQkDys FUN_000559-T1 118 GFGGKYGVQKDRVDQAAVGFEYEGKTEKHESQKDYS 153 9**********************************8 PP == domain 3 score: 69.6 bits; conditional E-value: 9.7e-23 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekvekHeSQkDys 36 GFGGK+GVqkDr Dk+AvGw+y++k+++H+SQkDys FUN_000559-T1 155 GFGGKYGVQKDRIDKAAVGWEYEGKTDAHASQKDYS 190 9**********************************8 PP == domain 4 score: 67.3 bits; conditional E-value: 4.9e-22 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekvekHeSQkDys 36 GFGGK+GVqkDrvDk+AvG++y++k+e+H+SQ D+s FUN_000559-T1 192 GFGGKYGVQKDRVDKAAVGFEYEGKTEAHASQLDHS 227 9*********************************97 PP == domain 5 score: 68.1 bits; conditional E-value: 2.8e-22 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekvekHeSQkDys 36 GFGGKFGVqkD++Dk+AvG++y++k+e+H+SQkD+s FUN_000559-T1 229 GFGGKFGVQKDKMDKAAVGYEYEGKTEAHASQKDHS 264 9*********************************97 PP == domain 6 score: 70.1 bits; conditional E-value: 6.6e-23 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekvekHeSQkDys 36 GFGGKFGVqk+rvDksA+G++y++k+e+H+SQkDys FUN_000559-T1 266 GFGGKFGVQKERVDKSALGFEYEGKTEAHASQKDYS 301 9**********************************8 PP == domain 7 score: 34.4 bits; conditional E-value: 9.4e-12 HS1_rep 1 GFGGKFGVqkDrvDksAvGwdykekve 27 GFGG++GVq+Dr+D +A ++d+ ++v+ FUN_000559-T1 303 GFGGRYGVQSDRQDAAAGSYDEMQEVK 329 9*********************99885 PP >> SH3_1 SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.0 0.2 2.9e-21 9.4e-18 1 48 [] 487 532 .. 487 532 .. 0.97 Alignments for each domain: == domain 1 score: 64.0 bits; conditional E-value: 2.9e-21 SH3_1 1 vAlYDYeaeesdELsfkkGdviivleksedgWwkgrlkdggkeGliPs 48 +AlYDY+a +dE+sf +Gd+i+ +ek +dgWw+g ++ g++Gl+Ps FUN_000559-T1 487 TALYDYQADGDDEISFDPGDIITDIEKIDDGWWTGTCN--GQRGLFPS 532 59************************************..79*****8 PP >> SH3_9 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.5 0.1 9.1e-20 2.9e-16 1 49 [] 488 536 .. 488 536 .. 0.99 Alignments for each domain: == domain 1 score: 59.5 bits; conditional E-value: 9.1e-20 SH3_9 1 AlypyqpkeddeLslqeGdvitvieesedgWlegentGrtGlvPanyve 49 Aly+yq++ dde+s+++Gd+it ie+ +dgW+ g+ +G++Gl+P+n+ve FUN_000559-T1 488 ALYDYQADGDDEISFDPGDIITDIEKIDDGWWTGTCNGQRGLFPSNFVE 536 9***********************************************7 PP >> SH3_2 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 1.3 4e+03 29 43 .. 94 109 .. 88 110 .. 0.77 2 ? -3.7 0.0 4.6 1.5e+04 29 40 .. 168 180 .. 167 183 .. 0.79 3 ! 35.6 0.0 2.4e-12 7.6e-09 5 54 .. 489 537 .. 486 538 .] 0.94 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 1.3 SH3_2 29 gkdddgw.wegetgGr 43 +k+ gw +eg ++++ FUN_000559-T1 94 DKNVVGWdYEGKVDKH 109 466679****998776 PP == domain 2 score: -3.7 bits; conditional E-value: 4.6 SH3_2 29 gkdddgw.weget 40 +k++ gw +eg t FUN_000559-T1 168 DKAAVGWeYEGKT 180 5778899999976 PP == domain 3 score: 35.6 bits; conditional E-value: 2.4e-12 SH3_2 5 ifdyvgtdkngLslkkGdvvkVlggkdddgwwegetgGrkGlvPstavee 54 + dy + ++s+ Gd+++ + +k ddgww g ++G++Gl+Ps++vee FUN_000559-T1 489 LYDYQADGDDEISFDPGDIITDI-EKIDDGWWTGTCNGQRGLFPSNFVEE 537 5689999999*************.************************98 PP >> TMEM210 TMEM210 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.023 75 56 71 .. 83 98 .. 65 111 .. 0.83 2 ? 5.2 0.0 0.013 42 54 74 .. 118 138 .. 103 141 .. 0.78 3 ! 6.0 0.0 0.0071 23 52 73 .. 153 174 .. 134 183 .. 0.75 4 ! 5.7 0.0 0.0089 28 52 74 .. 190 212 .. 176 215 .. 0.74 5 ! 8.1 0.0 0.0016 5.2 43 73 .. 216 248 .. 207 251 .. 0.71 6 ? 2.9 0.0 0.065 2.1e+02 50 71 .. 262 283 .. 250 289 .. 0.68 7 ? 1.4 0.0 0.19 6e+02 51 68 .. 300 317 .. 282 327 .. 0.73 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.023 TMEM210 56 vghfGvqedrldlhtv 71 g+fGvq+dr+d + v FUN_000559-T1 83 GGKFGVQKDRIDKNVV 98 589*********8776 PP == domain 2 score: 5.2 bits; conditional E-value: 0.013 TMEM210 54 rlvghfGvqedrldlhtvhve 74 + g++Gvq+dr+d +v e FUN_000559-T1 118 GFGGKYGVQKDRVDQAAVGFE 138 56799*********9998766 PP == domain 3 score: 6.0 bits; conditional E-value: 0.0071 TMEM210 52 dnrlvghfGvqedrldlhtvhv 73 + + g++Gvq+dr+d +v FUN_000559-T1 153 SKGFGGKYGVQKDRIDKAAVGW 174 455779**********998865 PP == domain 4 score: 5.7 bits; conditional E-value: 0.0089 TMEM210 52 dnrlvghfGvqedrldlhtvhve 74 + + g++Gvq+dr+d +v e FUN_000559-T1 190 SKGFGGKYGVQKDRVDKAAVGFE 212 455779**********9998766 PP == domain 5 score: 8.1 bits; conditional E-value: 0.0016 TMEM210 43 kgetcprhvd..nrlvghfGvqedrldlhtvhv 73 k+e+ +++ d + + g+fGvq+d++d +v FUN_000559-T1 216 KTEAHASQLDhsKGFGGKFGVQKDKMDKAAVGY 248 55555555551134679**********998865 PP == domain 6 score: 2.9 bits; conditional E-value: 0.065 TMEM210 50 hvdnrlvghfGvqedrldlhtv 71 + + g+fGvq++r+d ++ FUN_000559-T1 262 DHSKGFGGKFGVQKERVDKSAL 283 33345789*********98765 PP == domain 7 score: 1.4 bits; conditional E-value: 0.19 TMEM210 51 vdnrlvghfGvqedrldl 68 + + g++Gvq dr d FUN_000559-T1 300 YSKGFGGRYGVQSDRQDA 317 3455789********996 PP >> CjCas9_WED-like CRISPR-associated endonuclease CjCas9 wedge domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.6 0.11 3.4e+02 14 23 .. 81 90 .. 69 90 .. 0.79 2 ! 6.7 0.7 0.0024 7.8 6 23 .. 110 127 .. 107 127 .. 0.92 3 ! 7.8 3.4 0.0011 3.6 3 23 .. 144 164 .. 142 164 .. 0.88 4 ! 10.1 0.5 0.00022 0.71 6 23 .. 184 201 .. 180 201 .. 0.92 5 ? 3.1 0.1 0.033 1e+02 7 23 .. 222 238 .. 217 238 .. 0.80 6 ! 5.9 0.4 0.0043 14 3 23 .. 255 275 .. 253 275 .. 0.89 7 ! 7.1 0.3 0.0018 5.9 3 22 .. 292 311 .. 290 312 .. 0.88 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.11 CjCas9_WED-like 14 sYGGeEGvkK 23 YGG+ Gv+K FUN_000559-T1 81 GYGGKFGVQK 90 5********9 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0024 CjCas9_WED-like 6 yskekllksYGGeEGvkK 23 +s++++ +GG+ Gv+K FUN_000559-T1 110 ASQKDYATGFGGKYGVQK 127 579**************9 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0011 CjCas9_WED-like 3 eTfyskekllksYGGeEGvkK 23 e s++++ k +GG+ Gv+K FUN_000559-T1 144 EKHESQKDYSKGFGGKYGVQK 164 556789**************9 PP == domain 4 score: 10.1 bits; conditional E-value: 0.00022 CjCas9_WED-like 6 yskekllksYGGeEGvkK 23 +s++++ k +GG+ Gv+K FUN_000559-T1 184 ASQKDYSKGFGGKYGVQK 201 689**************9 PP == domain 5 score: 3.1 bits; conditional E-value: 0.033 CjCas9_WED-like 7 skekllksYGGeEGvkK 23 s+ + k +GG+ Gv+K FUN_000559-T1 222 SQLDHSKGFGGKFGVQK 238 56677899********9 PP == domain 6 score: 5.9 bits; conditional E-value: 0.0043 CjCas9_WED-like 3 eTfyskekllksYGGeEGvkK 23 e +s+++ k +GG+ Gv+K FUN_000559-T1 255 EAHASQKDHSKGFGGKFGVQK 275 666889**************9 PP == domain 7 score: 7.1 bits; conditional E-value: 0.0018 CjCas9_WED-like 3 eTfyskekllksYGGeEGvk 22 e +s++++ k +GG Gv+ FUN_000559-T1 292 EAHASQKDYSKGFGGRYGVQ 311 66789*************98 PP >> Endonuc_subdom PI-PfuI Endonuclease subdomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 4.6 1.5e+04 62 72 .. 82 92 .. 79 112 .. 0.79 2 ? 1.9 0.1 0.17 5.6e+02 56 72 .. 114 129 .. 87 135 .. 0.78 3 ? 5.2 0.1 0.017 55 44 72 .. 139 166 .. 136 172 .. 0.82 4 ? 3.9 0.0 0.043 1.4e+02 56 72 .. 188 203 .. 174 210 .. 0.78 5 ? 0.1 0.0 0.66 2.1e+03 56 72 .. 225 240 .. 209 247 .. 0.77 6 ? 0.6 0.0 0.46 1.5e+03 47 72 .. 253 277 .. 242 281 .. 0.75 7 ? 2.9 0.0 0.086 2.7e+02 46 73 .. 289 315 .. 277 319 .. 0.79 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 4.6 Endonuc_subdom 62 fgkkyslqkdr 72 +g k+ +qkdr FUN_000559-T1 82 YGGKFGVQKDR 92 78899999988 PP == domain 2 score: 1.9 bits; conditional E-value: 0.17 Endonuc_subdom 56 dylektfgkkyslqkdr 72 dy fg ky +qkdr FUN_000559-T1 114 DY-ATGFGGKYGVQKDR 129 44.4579*********9 PP == domain 3 score: 5.2 bits; conditional E-value: 0.017 Endonuc_subdom 44 ydyrietleiindylektfgkkyslqkdr 72 y+ ++e e +dy k fg ky +qkdr FUN_000559-T1 139 YEGKTEKHESQKDY-SKGFGGKYGVQKDR 166 55567777777787.699**********9 PP == domain 4 score: 3.9 bits; conditional E-value: 0.043 Endonuc_subdom 56 dylektfgkkyslqkdr 72 dy k fg ky +qkdr FUN_000559-T1 188 DY-SKGFGGKYGVQKDR 203 44.799**********9 PP == domain 5 score: 0.1 bits; conditional E-value: 0.66 Endonuc_subdom 56 dylektfgkkyslqkdr 72 d+ k fg k+ +qkd+ FUN_000559-T1 225 DH-SKGFGGKFGVQKDK 240 44.589*********97 PP == domain 6 score: 0.6 bits; conditional E-value: 0.46 Endonuc_subdom 47 rietleiindylektfgkkyslqkdr 72 ++e+ +d+ k fg k+ +qk+r FUN_000559-T1 253 KTEAHASQKDH-SKGFGGKFGVQKER 277 55555556666.699*********98 PP == domain 7 score: 2.9 bits; conditional E-value: 0.086 Endonuc_subdom 46 yrietleiindylektfgkkyslqkdrn 73 ++e+ +dy k fg +y +q dr+ FUN_000559-T1 289 GKTEAHASQKDY-SKGFGGRYGVQSDRQ 315 456666666666.699**********96 PP >> zf-CCHC_4 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.039 1.3e+02 13 28 .. 125 140 .. 123 141 .. 0.89 2 ? -2.9 0.0 2.5 7.9e+03 13 28 .. 162 177 .. 162 177 .. 0.82 3 ? 2.8 0.0 0.039 1.3e+02 13 28 .. 199 214 .. 196 215 .. 0.89 4 ? -0.4 0.0 0.42 1.3e+03 13 28 .. 236 251 .. 235 252 .. 0.91 5 ? 1.5 0.0 0.11 3.4e+02 13 28 .. 273 288 .. 272 289 .. 0.88 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.039 zf-CCHC_4 13 ikfesgewalieFkYE 28 ++++ ++a+++F+YE FUN_000559-T1 125 VQKDRVDQAAVGFEYE 140 67888899*******9 PP == domain 2 score: -2.9 bits; conditional E-value: 2.5 zf-CCHC_4 13 ikfesgewalieFkYE 28 ++++ ++a+++ +YE FUN_000559-T1 162 VQKDRIDKAAVGWEYE 177 5677778999*****9 PP == domain 3 score: 2.8 bits; conditional E-value: 0.039 zf-CCHC_4 13 ikfesgewalieFkYE 28 ++++ ++a+++F+YE FUN_000559-T1 199 VQKDRVDKAAVGFEYE 214 78888899*******9 PP == domain 4 score: -0.4 bits; conditional E-value: 0.42 zf-CCHC_4 13 ikfesgewalieFkYE 28 ++++ ++a+++++YE FUN_000559-T1 236 VQKDKMDKAAVGYEYE 251 7899999********9 PP == domain 5 score: 1.5 bits; conditional E-value: 0.11 zf-CCHC_4 13 ikfesgewalieFkYE 28 +++e ++++++F+YE FUN_000559-T1 273 VQKERVDKSALGFEYE 288 678888999******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (538 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3272 (0.128088); expected 510.9 (0.02) Passed bias filter: 978 (0.0382854); expected 510.9 (0.02) Passed Vit filter: 305 (0.0119397); expected 25.5 (0.001) Passed Fwd filter: 57 (0.00223136); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.53u 0.44s 00:00:00.97 Elapsed: 00:00:00.42 # Mc/sec: 5151.80 // Query: FUN_000561-T1 [L=133] Description: FUN_000561 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (133 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 364 (0.0142494); expected 510.9 (0.02) Passed bias filter: 342 (0.0133881); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1340.69 // Query: FUN_000562-T1 [L=1545] Description: FUN_000562 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-30 104.5 15.2 3e-13 50.2 0.9 3.7 3 Beta-prop_WDR5 WDR5 beta-propeller domain 1.9e-28 99.7 9.0 1.9e-11 43.9 0.1 4.8 5 Beta-prop_THOC3 THOC3 beta-propeller domain 1.2e-25 90.7 14.5 7.3e-10 39.3 0.0 5.4 4 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 3e-24 86.0 2.5 5e-06 26.3 0.0 5.1 5 WD40_Prp19 Prp19 WD40 domain 5.7e-20 72.3 8.1 1.6e-06 28.2 0.1 4.6 5 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 9.6e-20 71.5 13.7 3.7e-07 30.1 0.0 5.6 4 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 2.4e-18 66.8 5.8 5.7e-10 39.3 0.2 4.6 4 EIF3I EIF3I 9.5e-17 61.6 0.0 2.6e-16 60.1 0.0 1.7 1 WHD_NWD1 NWD1-like, winged helix-turn-helix 3.7e-14 53.2 15.7 3.4e-07 30.3 0.3 5.6 7 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 7.4e-14 52.0 7.7 8.4e-06 25.5 0.1 5.1 5 WDR55 WDR55 1.4e-13 51.3 7.9 0.0013 18.6 0.2 5.7 5 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 7.5e-13 48.9 0.7 0.0047 16.8 0.0 5.2 5 Beta-prop_EML_2 Echinoderm microtubule-associated 1.7e-12 47.7 14.5 5.1e-05 24.1 0.2 6.4 5 WD40 WD domain, G-beta repeat 2.8e-10 40.8 0.5 0.019 15.7 0.0 6.5 6 ANAPC4_WD40 Anaphase-promoting complex subunit 4.7e-10 40.7 0.0 3.1e-09 38.1 0.0 2.4 1 AAA_16 AAA ATPase domain 1e-09 38.3 5.4 1.5e-05 24.6 0.3 4.4 4 WD40_Gbeta G protein beta WD-40 repeat protei 1.4e-08 34.8 4.6 7.1e-05 22.6 0.0 3.3 3 Beta-prop_NWD2_C NWD2 C-terminal beta-propeller 4e-08 34.1 0.1 1.3e-07 32.4 0.1 2.0 1 NPHP3_N Nephrocystin 3, N-terminal 5.5e-08 33.3 0.0 1.3e-07 32.1 0.0 1.6 1 NACHT NACHT domain 7.1e-08 32.4 7.6 4.6e-05 23.2 0.5 4.8 4 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 1.3e-07 31.9 7.8 0.017 15.1 0.1 6.2 7 Beta-prop_EML Echinoderm microtubule-associated 4.3e-07 29.9 7.6 5.3e-05 23.0 0.6 4.5 5 WD40_WDHD1_1st WDHD1 first WD40 domain 9.7e-07 29.2 0.0 1.5e-06 28.6 0.0 1.3 1 nSTAND1 Novel STAND NTPase 1 2.9e-06 27.1 1.8 3.4e-05 23.6 0.2 2.8 3 Beta-prop_Aladin Aladin seven-bladed propeller 4.9e-06 27.0 0.0 1.7e-05 25.3 0.0 1.9 1 ATPase_2 ATPase domain predominantly from A 5.6e-06 26.7 3.1 1.2 9.7 0.2 4.7 4 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 1.1e-05 25.5 5.7 0.0054 16.6 0.2 3.0 2 WD40_like WD40-like domain 1.9e-05 25.6 0.0 9.2e-05 23.4 0.0 2.3 1 AAA ATPase family associated with vari 2e-05 24.2 11.2 0.33 10.3 0.1 5.2 7 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 7.1e-05 22.4 2.5 0.0012 18.3 0.2 3.7 3 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 9.8e-05 22.3 0.3 0.36 10.6 0.0 3.4 3 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 0.00019 22.2 0.0 0.001 19.9 0.0 2.3 1 AAA_22 AAA domain 0.00036 21.1 0.0 0.0022 18.6 0.0 2.4 1 DUF4062 Domain of unknown function (DUF406 0.00045 19.7 5.0 0.22 10.8 0.1 3.6 3 NBCH_WD40 Neurobeachin beta propeller domain 0.0007 20.2 0.0 0.0026 18.3 0.0 2.0 1 Torsin Torsin 0.00097 18.7 6.9 0.31 10.4 0.8 4.6 3 Beta-prop_VPS8 Vps8 beta-propeller 0.0011 19.6 0.0 0.0037 18.0 0.0 1.8 1 Bac_DnaA Bacterial DnaA ATPAse domain 0.0017 18.9 0.0 0.0045 17.5 0.0 1.8 1 nSTAND6 Novel STAND NTPase 6 0.0027 17.9 0.0 0.025 14.7 0.0 2.6 2 nSTAND3 Novel STAND NTPase 3 0.0079 16.5 0.5 0.023 15.0 0.5 1.8 1 HRI2_3H Heme-regulated eIF-2-alpha kinase, ------ inclusion threshold ------ 0.014 15.4 0.0 0.038 14.0 0.0 1.8 1 NB-ARC NB-ARC domain 0.015 16.4 0.0 0.047 14.8 0.0 1.8 1 ABC_tran ABC transporter 0.02 14.1 0.4 2.5 7.2 0.0 3.5 4 Beta-prop_IFT140_1st IFT140 first beta-propeller 0.028 15.4 0.0 0.081 13.9 0.0 1.8 1 RNA_helicase RNA helicase 0.028 14.4 0.1 3.2 7.7 0.0 3.8 4 B-prop_COPA_B_2nd COPA/B second beta-propeller 0.055 13.4 0.0 0.21 11.5 0.0 2.0 1 Zeta_toxin Zeta toxin 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 TniB Bacterial TniB protein 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 Rad17 Rad17 P-loop domain 0.16 12.1 0.0 0.34 11.0 0.0 1.4 1 ATP-synt_ab ATP synthase alpha/beta family, nu Domain annotation for each model (and alignments): >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.2 0.9 5.7e-16 3e-13 82 213 .. 824 955 .. 816 1028 .. 0.81 2 ! 36.8 3.4 7.1e-12 3.7e-09 29 260 .. 1049 1283 .. 1035 1294 .. 0.81 3 ! 23.3 0.1 9.2e-08 4.8e-05 73 191 .. 1367 1490 .. 1314 1505 .. 0.72 Alignments for each domain: == domain 1 score: 50.2 bits; conditional E-value: 5.7e-16 Beta-prop_WDR5 82 llktlkgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnp 176 l++ ++gH+ +++++ +++g+ll+S+ +D t +Wdv++g++++t+++ + v+ v+++ d++l+v+s++ i w ++gq + ++ +d+ FUN_000562-T1 824 LIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTSAIS-SISAWRLSNGQRMFSVSQDHAI 917 578899************************************************************999985.6899**********99988777 PP Beta-prop_WDR5 177 pvsfvkF.spngkyiLastldstirLwdyekekvvktY 213 + + + + ++a+ + s+i+L+d++ + + + FUN_000562-T1 918 YAAPICLlEKEKRILMAAFIKSSIKLYDLQAGSLALEI 955 5555555055555666777899*****99987765554 PP == domain 2 score: 36.8 bits; conditional E-value: 7.1e-12 Beta-prop_WDR5 29 tikiwdveegklektleghkkGisdvawssd.........skllasaSDD...ktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSGs 109 t+++wd+++ ++++l + ++ + ++ s d s+ saS ++i+d+ +g++++ + + + + v++ ++ ++++s FUN_000562-T1 1049 TLELWDLKRKIVVHQLVEPSSKVRCFTLSMDkskaltlgnSR--FSASANvfhAEIKIFDLVSGEIIQWMLKYPSSIHLVQYID-SSHVITAS 1138 567788888778888888888888877777753333332233..35555322268***************************76.667889** PP Beta-prop_WDR5 110 fDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvsfvkFspngkyiLastldstirLw 202 D+ +rlWd++++ ++ ++ v++ + + +r+ d + g+ ++ + +p++ F ++k iL+s ++ L+ FUN_000562-T1 1139 RDKIIRLWDLKRSAPPSAVEELKEEQAEVEIVGMYGHHAICWEKHALRVVDLQAGHFIHFVN-GVKPQI---VFVDDNKAILVSC--GKMSLF 1225 ************988777777777777777776666677789999*************9874.555555...5678999999987..799*** PP Beta-prop_WDR5 203 dyekekvvktYkghknekycisaefsetggklvvsGsedgkvyiwdlqskeivqkleg 260 d++k++++ +++g ++ + +f++t++++v+ s++++++++d++s + ++++++ FUN_000562-T1 1226 DLNKNQMIVQFEGGIWDEGLANGCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQMKC 1283 *************************************************998888874 PP == domain 3 score: 23.3 bits; conditional E-value: 9.2e-08 Beta-prop_WDR5 73 riwdvetgkllktlkgHtny.vfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktl.paHsdpvsavdfnrdgtlivss.....syDgliri 158 ++dvetgkl ++ tny v + p++ l+ G fD +++l d+ tgkcl+ + aH v ++ + dgt+ +++ s D ir FUN_000562-T1 1367 VVFDVETGKL--LFESATNYqVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRInRAHLGSVHRISTTDDGTVAMTTaggldSKDRSIRF 1457 3677788887..445555543666666799999999******************999469***************988875666689****** PP Beta-prop_WDR5 159 wdtetgqclktlveddnppvsfvkFspngkyiL 191 w+ ++ ++ v +++vs+++ s +g ++ FUN_000562-T1 1458 WNLDKDRMELLTVFTPDAKVSSMNISSDGFFVA 1490 *99887664433445678899999999988875 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.9 0.1 3.7e-14 1.9e-11 159 257 .. 820 917 .. 812 921 .. 0.91 2 ? 2.9 0.1 0.12 63 194 229 .. 1049 1085 .. 1000 1114 .. 0.85 3 ! 25.2 0.7 2e-08 1e-05 65 255 .. 1093 1285 .. 1049 1300 .. 0.80 4 ! 10.7 0.1 0.00053 0.27 55 144 .. 1251 1352 .. 1243 1366 .. 0.77 5 ! 30.1 0.1 6e-10 3.2e-07 72 232 .. 1318 1493 .. 1311 1502 .. 0.81 Alignments for each domain: == domain 1 score: 43.9 bits; conditional E-value: 3.7e-14 Beta-prop_THOC3 159 psleevktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvsFShdGkllAsasedktidiasvetgesvhtik 252 p + ++++++h+ +++++ + +g++lA++ D++ s+WD++++ +rt++++ + v v++S d +l++ s + i+ + +++g+++ +++ FUN_000562-T1 820 PGGPLIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVV-TSAISSISAWRLSNGQRMFSVS 912 556679************************************************************98766.678899*************999 PP Beta-prop_THOC3 253 teaav 257 ++a+ FUN_000562-T1 913 QDHAI 917 87765 PP == domain 2 score: 2.9 bits; conditional E-value: 0.12 Beta-prop_THOC3 194 lvslWDleeliclrtltrlespvrsvsFShd.GkllA 229 + +lWDl++ i ++ l + +s+vr+ S+d +k l FUN_000562-T1 1049 TLELWDLKRKIVVHQLVEPSSKVRCFTLSMDkSKALT 1085 678**************************87345555 PP == domain 3 score: 25.2 bits; conditional E-value: 2e-08 Beta-prop_THOC3 65 ass...DktvrlWdvrtgkstatvktkgeninlawspdGktiavgskddtvslidvrtgkv.kkeekfkkevnevafspdgkllllttgdgt 152 as+ ++++d+ +g+ ++ + + i+l d ++++++s+d+ ++l+d+++ + e+ k+e ev+ + +++ +++ FUN_000562-T1 1093 ASAnvfHAEIKIFDLVSGEIIQWMLKYPSSIHLVQYIDSSHVITASRDKIIRLWDLKRSAPpSAVEELKEEQAEVEIVGMYGHHAICWEKHA 1184 333235678**************9999999999999*********************98763677889999999999999999999****** PP Beta-prop_THOC3 153 vevlsypsleevktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltr..lesp.vrsvsFShdGkllAsasedktidias 241 ++v++++ + ++ +++ + +++ v d ++ +l+++++ +sl+Dl++ +++ +++ +++ + + + + +++A+ s++k + +++ FUN_000562-T1 1185 LRVVDLQAGHFIHFVNGVKPQIVFV--DDNKAILVSCGK---MSLFDLNKNQMIVQFEGgiWDEGlANGCFIHTTHEVVAVNSDQKSLCVYD 1271 *********************9998..89999*****96...899***999999999973344442455555667899************** PP Beta-prop_THOC3 242 vetgesvhtiktea 255 +++g+++ ++k+e+ FUN_000562-T1 1272 MHSGQRISQMKCEH 1285 **********9985 PP == domain 4 score: 10.7 bits; conditional E-value: 0.00053 Beta-prop_THOC3 55 spthpdllatassDktvrlWdvrtgkstatvktkgeninlawspdGktiavg..........skddtvslidvrtgkv...kkeekfkkevn 133 +t ++++a s+ k++ ++d+++g+ ++++k+++ +p+G +++ g ++ +s++++++ k + +e+ ++++n FUN_000562-T1 1251 IHTTHEVVAVNSDQKSLCVYDMHSGQRISQMKCEHIR-RFVHTPNGDICVLGhsmindeepaKSRYFLSVWNIKQRKRvrdIDQENVETDFN 1341 4556689999******************999987655.46689*********4444333332235799******98862223456667889* PP Beta-prop_THOC3 134 evafspdgkll 144 e++ +dg+ll FUN_000562-T1 1342 EMQLVKDGSLL 1352 **999999987 PP == domain 5 score: 30.1 bits; conditional E-value: 6e-10 Beta-prop_THOC3 72 rlWdvrtgkstatvktkgen..in.lawspdGkti..avg...skddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgdgtvev 155 +W+++++k ++ ++ ++ +n ++ +dG+ + +v sk ++dv+tgk e+ ++++v++ p+ ++lll+ dg +++ FUN_000562-T1 1318 SVWNIKQRKRVRDIDQENVEtdFNeMQLVKDGSLLsdIVYdlqSKVYRAVVFDVETGKLLFESATNYQVHTSVILPETRHLLLGLFDGAIQL 1409 6899999999999987554311334999999998733233111333344588**************************************** PP Beta-prop_THOC3 156 lsypsleevktlk.ahtsnclcvafdpkgrylAvG.....saDalvslWDle.eliclrtltrlespvrsvsFShdGkllAsas 232 ++ +++++++++ ah +++ ++ +g++ + s+D ++ W+l+ + + l t+ + +v s+++S+dG ++A FUN_000562-T1 1410 DDIDTGKCLHRINrAHLGSVHRISTTDDGTVAMTTaggldSKDRSIRFWNLDkDRMELLTVFTPDAKVSSMNISSDGFFVALEL 1493 **********98559**********9999854332233556899*******856788999999*****************9865 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.0 1.4e-12 7.3e-10 65 183 .. 826 945 .. 820 946 .. 0.81 2 ! 20.7 0.9 7.3e-07 0.00038 55 146 .. 1052 1152 .. 1050 1175 .. 0.65 3 ! 7.6 0.4 0.0075 3.9 23 170 .. 1158 1298 .. 1151 1304 .. 0.74 4 ! 25.6 0.2 2.2e-08 1.2e-05 12 167 .. 1318 1486 .. 1313 1494 .. 0.78 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 1.4e-12 Beta-prop_WDR3_1st 65 vtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvk.tlvgh 154 +++gH+ +tal+ ++dg+ Las+ D++ vwDv +++ + +++g ++v +va++ ++ lv +S + i W l++++ + ++h FUN_000562-T1 826 HSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDN-SLVVTSAISSISAWRLSNGQRMFsVSQDH 915 5789***************************************************999886.5666667799******9976655055566 PP Beta-prop_WDR3_1st 155 rsevwslalskdek.llvtgssdselrvwk 183 ++l ++ek +l+++ s++++++ FUN_000562-T1 916 AIYAAPICLLEKEKrILMAAFIKSSIKLYD 945 666666776666551566777788888876 PP == domain 2 score: 20.7 bits; conditional E-value: 7.3e-07 Beta-prop_WDR3_1st 55 lwdlesgelevtfngHksavtalafdkdgsr.L......asGskD...tdiivwDvvaeaglfrLkgHkdqvtsvafleekkvlvssSk 133 lwdl+++ + ++ +s+v + + + d+s+ L +s+s++ +i ++D+v+++ + + +++ v+++++ ++++++S+ FUN_000562-T1 1052 LWDLKRKIVVHQLVEPSSKVRCFTLSMDKSKaLtlgnsrFSASANvfhAEIKIFDLVSGEIIQWMLKYPSSIHLVQYIDS-SHVITASR 1139 66666666666666666666665555443321111222245555422258999999999999999999999999999987.57899999 PP Beta-prop_WDR3_1st 134 DtliklWdletqh 146 D++i+lWdl+ + FUN_000562-T1 1140 DKIIRLWDLKRSA 1152 9999999999864 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0075 Beta-prop_WDR3_1st 23 atlegeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkg 111 +l++e++ev+ + + + a+ + ++r+ dl+ g+ ng k ++ + d++++ L+s++k + ++D+ +++ +++++g FUN_000562-T1 1158 EELKEEQAEVEIVGMYG---HHAICWEKHALRVVDLQAGHFIHFVNGVKPQIVFV--DDNKAILVSCGK---MSLFDLNKNQMIVQFEG 1238 55666666666666544...66888899999999999999999999999999887..677899999986...78999999999999999 PP Beta-prop_WDR3_1st 112 ...HkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekll 170 ++ + + + ++++v++ S+ + + ++d+++++ + ++ +++ ++ +++++++ FUN_000562-T1 1239 giwDEGLANGCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQMKC--EHIRRFVHTPNGDIC 1298 443345555555556788888889999999999999988877654..345555555555555 PP == domain 4 score: 25.6 bits; conditional E-value: 2.2e-08 Beta-prop_WDR3_1st 12 lvWdlkkgekvatlege..ksevtalaaspdgkklavGyadgsir.....lwdlesgelevtfngHksavtalafdkdgsrLasGskDt 93 vW++k++++v+ +++e +++ + ++ +dg+ l d + + ++d+e+g+l + ++ + +v + ++ +L G D FUN_000562-T1 1318 SVWNIKQRKRVRDIDQEnvETDFNEMQLVKDGSLLSDIVYDLQSKvyravVFDVETGKLLFE-SATNYQVHTSVILPETRHLLLGLFDG 1405 69**********99765125667778888888777655555544400122667777766544.44556777777889999999****** PP Beta-prop_WDR3_1st 94 diivwDvvaeaglfrLk.gHkdqvtsvafleekkvlvss.....SkDtliklWdletqh.cvktlvghrsevwslalskde 167 i + D+ ++++l+r++ H ++v +++ ++++v +++ SkD+ i++W+l++ + + t+ +++v s+++s+d+ FUN_000562-T1 1406 AIQLDDIDTGKCLHRINrAHLGSVHRISTTDDGTVAMTTaggldSKDRSIRFWNLDKDRmELLTVFTPDAKVSSMNISSDG 1486 ****************659**************999887666669**********9865268999***********99986 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.0 9.6e-09 5e-06 44 177 .. 827 959 .. 817 971 .. 0.53 2 ? -0.4 0.0 1.3 6.9e+02 201 229 .. 1050 1079 .. 1042 1101 .. 0.61 3 ! 17.4 0.0 4.8e-06 0.0025 30 132 .. 1101 1202 .. 1098 1242 .. 0.78 4 ! 12.3 0.1 0.00018 0.091 96 177 .. 1248 1335 .. 1207 1352 .. 0.79 5 ! 25.8 0.0 1.3e-08 6.7e-06 52 198 .. 1340 1495 .. 1319 1535 .. 0.76 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 9.6e-09 WD40_Prp19 44 tlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgdylvsaskDgtwalhdletgktllkvkdeeskeait 139 +++gh+ +ta+ + + ++l sa D+t vw+ ++ + + t++ ++v +++ ++++v++ + ++++ + l++g+++ +v+++++ a FUN_000562-T1 827 SMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTS-AISSISAWRLSNGQRMFSVSQDHAIYAAP 921 555555555555555555555555555555555555555555555555555555555444444443.33445555555555555555555544555 PP WD40_Prp19 140 saqfHPDGlllgtGtkdgtvkiWDiksqknvasleghs 177 + + +l ++ ++++k++D++ ++ + ++++ s FUN_000562-T1 922 ICLLEKEKRILMAAFIKSSIKLYDLQAGSLALEIDDNS 959 55555555555555555555555555555555554433 PP == domain 2 score: -0.4 bits; conditional E-value: 1.3 WD40_Prp19 201 vklWDLRklknfktl.eldeeskvnsvaFD 229 +lWDL+++ ++++l e +++ ++ ++++D FUN_000562-T1 1050 LELWDLKRKIVVHQLvEPSSKVRCFTLSMD 1079 556666554444443133334444445555 PP == domain 3 score: 17.4 bits; conditional E-value: 4.8e-06 WD40_Prp19 30 nvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgdylvsaskDgtwalhdletg 123 ++ +fd s+++++ + + + v++ +s + +++as Dk +r+w+ + + +++++ k+e ++++ + + + + + ++ + dl++g FUN_000562-T1 1101 EIKIFDLVSGEIIQWMLKYPSSIHLVQYIDS-SHVITASRDKIIRLWDLKRSAPPSAVEELKEEQAEVEIVGMYGHHAICWEKHALRVVDLQAG 1193 6899***********************9955.7899**************99888888888888888888888888888999999999999999 PP WD40_Prp19 124 ktllkvkde 132 + ++ v+ FUN_000562-T1 1194 HFIHFVNGV 1202 998877654 PP == domain 4 score: 12.3 bits; conditional E-value: 0.00018 WD40_Prp19 96 slsvhptgdylvsaskDgtwalhdletgktllkvkdeeskeaitsaqfHPDGlllgtGtk..........dgtvkiWDiksqknvasleghs 177 + +h t+++++ s+++++ ++d+++g+++ ++k e +i + P+G ++ +G + ++++W+ik++k v ++++++ FUN_000562-T1 1248 GCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQMKCE----HIRRFVHTPNGDICVLGHSmindeepaksRYFLSVWNIKQRKRVRDIDQEN 1335 5669***************************999875....47888889*******997522222222114579999999999999987654 PP == domain 5 score: 25.8 bits; conditional E-value: 1.3e-08 WD40_Prp19 52 vtavafhpsedvlvsasaDktvrvwkk...eeketaatlkkhka.evtslsvhptgdylvsaskDgtwalhdletgktllkvkdeeskeaitsa 141 ++++++++ ++l D + +v+++ + ++ + ++++ ++ +v + + p ++l+ + Dg+++l d++tgk+l++++ ++ +++ + FUN_000562-T1 1340 FNEMQLVKDGSLLSDIVYDLQSKVYRAvvfDVETGKLLFESATNyQVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRINRAHL-GSVHRI 1432 5666677777777777778888888763333445566677655449999999******************************98766.59**** PP WD40_Prp19 142 qfHPDGlllgtG.....tkdgtvkiWDiksqkn.vasleghsgavtslaFSeNGYyLAsased 198 + DG+++ t +kd+++++W++ + ++ + ++ ++v+s+++S +G+ A +d FUN_000562-T1 1433 STTDDGTVAMTTaggldSKDRSIRFWNLDKDRMeLLTVFTPDAKVSSMNISSDGFFVALELTD 1495 ******997543122336899*******886641455566779************99976655 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.1 1.4e-05 0.0074 142 249 .. 824 929 .. 821 936 .. 0.90 2 ! 15.9 0.1 1.8e-05 0.0094 131 243 .. 855 968 .. 850 985 .. 0.81 3 ? -0.0 0.0 1.3 6.8e+02 132 157 .. 1050 1075 .. 1045 1087 .. 0.78 4 ! 27.1 0.5 7e-09 3.6e-06 65 236 .. 1120 1286 .. 1089 1305 .. 0.84 5 ! 28.2 0.1 3.1e-09 1.6e-06 87 231 .. 1317 1469 .. 1295 1485 .. 0.81 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.4e-05 Beta-prop_WDR36-Utp21_1st 142 liytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssGdialwdLekr 225 li+++++ + +ital++s ++a + + ++ + +++ ++ + +++ + v+ ++ D++ l+++s+ +i w L+++ FUN_000562-T1 824 LIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNS--LVVTSAISSISAWRLSNG 905 89***********************************************999*********965..99999999********** PP Beta-prop_WDR36-Utp21_1st 226 rlvhvlrnaHeggvtkleflpgqp 249 +++ +++ H+ + + l++++ FUN_000562-T1 906 QRMFSVSQDHAIYAAPICLLEKEK 929 999999999987777777776665 PP == domain 2 score: 15.9 bits; conditional E-value: 1.8e-05 Beta-prop_WDR36-Utp21_1st 131 slqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeeg.pvtsisFrtDgepvlatgss 213 + +w++++g+l+ tf+++++ + ++ s ++v + a +i + ++++++++q+++ i+ ++ +l+++ FUN_000562-T1 855 TCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLV-VTSAISSISAWRLSNGQRMFSVSQDHAiYAAPICLLEKEKRILMAAFI 937 6789*******************999888666555.6677779******************663566688888999******** PP Beta-prop_WDR36-Utp21_1st 214 sGdialwdLekrrlvhvlrnaHeg.gvtkle 243 + +i l+dL+ ++l+ +++ e+ g+++ FUN_000562-T1 938 KSSIKLYDLQAGSLALEIDDNSESdGISSSL 968 ************9998888777655665543 PP == domain 3 score: -0.0 bits; conditional E-value: 1.3 Beta-prop_WDR36-Utp21_1st 132 lqlwNirtgkliytfksfksaitale 157 l+lw+++ + +++++ + +s++ +++ FUN_000562-T1 1050 LELWDLKRKIVVHQLVEPSSKVRCFT 1075 78888888888888888888887765 PP == domain 4 score: 27.1 bits; conditional E-value: 7e-09 Beta-prop_WDR36-Utp21_1st 65 eekikkllvfgd.hlvavdednsllvwkieteelyteiefseeefeitallhpsTYlnKilvgskqGslqlwNirtgkliyt 145 ++i+ + + + h++++++d+ +++w+++++ + +e +ee ++++ Y + k+ +l++++++ g+ i+ FUN_000562-T1 1120 PSSIHLVQYIDSsHVITASRDKIIRLWDLKRSAPPSAVEELKEEQAEVEIVG--MYGHHAICWEKH-ALRVVDLQAGHFIHF 1198 566666666665599****************977777766655555555554..488888888888.8************** PP Beta-prop_WDR36-Utp21_1st 146 fksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqe..egpvtsisFrtDgepvlatgsssGdialwdLekr 225 ++++k +i ++ ai ++ G++ l++++k++ +++++ ++ + +F + +++v a+ s++ +++++d+ ++ FUN_000562-T1 1199 VNGVKPQIVFVDDN-----KAILVSCGKMSLFDLNKNQMIVQFEGGiwDEGLANGCFIHTTHEVVAVNSDQKSLCVYDMHSG 1275 *********99865.....577889*******************98845699999*************************** PP Beta-prop_WDR36-Utp21_1st 226 rlvhvlrnaHe 236 +++++++ H FUN_000562-T1 1276 QRISQMKCEHI 1286 ******98885 PP == domain 5 score: 28.2 bits; conditional E-value: 3.1e-09 Beta-prop_WDR36-Utp21_1st 87 llvwkieteelyteiefsee..efeitallhpsTYlnKil..vgskqGslqlwNirtgkliytfksfksaitaleqspaldv 164 l vw+i++++ +++i+ ++ +f+ +l++ l i+ + sk + +++++tgkl++++ ++ ++ + + p FUN_000562-T1 1317 LSVWNIKQRKRVRDIDQENVetDFNEMQLVKDGSLLSDIVydLQSKVYRAVVFDVETGKLLFESA-TNYQVHTSVILPETRH 1397 6788888888888888776333777888888888888888334455556779***********75.899************* PP Beta-prop_WDR36-Utp21_1st 165 vaiglasGeivlhnikkdetllklkqe.egpvtsisFrtDgepvlatg....sssGdialwdLekrrlvhvl 231 + +gl +G i l +i++++ l +++ + g+v is Dg+ + t+ s++ +i +w+L+k r+ + FUN_000562-T1 1398 LLLGLFDGAIQLDDIDTGKCLHRINRAhLGSVHRISTTDDGTVAMTTAggldSKDRSIRFWNLDKDRMELLT 1469 *************************98579***************998444446889********9875544 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 2.9e-05 0.015 168 211 .. 825 868 .. 822 874 .. 0.90 2 ! 20.7 4.6 5.4e-07 0.00028 1 247 [. 876 1149 .. 876 1172 .. 0.63 3 ? 4.4 0.2 0.05 26 45 114 .. 1207 1277 .. 1177 1299 .. 0.56 4 ! 30.1 0.0 7.1e-10 3.7e-07 24 112 .. 1368 1463 .. 1354 1497 .. 0.78 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.9e-05 Beta-prop_WDR3_2nd 168 flslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchk 211 ++s+ Gh+lP+++l+ s D+kl++++ D + +w ++ G + + FUN_000562-T1 825 IHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVR 868 57899******************************999886655 PP == domain 2 score: 20.7 bits; conditional E-value: 5.4e-07 Beta-prop_WDR3_2nd 1 dvRavalssddklllsassesvkiwnvkslecirtiese...yalclafvpgdrhvlv.gtkdGklevldlasaelletieah...ega 82 dv va+s d++l+++++ +s+ w ++ + + +++ + ya ++++ ++ +l+ + + +++++dl++++l +i++ +g FUN_000562-T1 876 DVCHVAISLDNSLVVTSAISSISAWRLSNGQRMFSVSQDhaiYAAPICLLEKEKRILMaAFIKSSIKLYDLQAGSLALEIDDNsesDG- 963 7889*************************99999998652337778889988887665167899************999998733223. PP Beta-prop_WDR3_2nd 83 v.ws..valtpdekglvtggaD..kkvkfwefe..........lve.eeeskakklslkhtrt..lklsddvl.cvkvspdkkllaval 152 + s +++++d+ l++ +++ ++ w + +v+ +++++ + + ++++ + l l++ + k s+ + ++ + l FUN_000562-T1 964 IsSSlcLCTMEDQSVLYANTSNlaTTTTTWVRQanlhtydvldIVQiSSNQTVHFIGVTKMNQmlLALTEGSPnTKKESSVQTFFTLEL 1052 33441145556665554444331123333332211111111111111123333334443333211344444431334455566666677 PP Beta-prop_WDR3_2nd 153 lDstvkvfflDtlkfflslYGhklPvlsldissDskl...ivtgsaD...knikiwGldfGDchkslfahddsvmsvafvpktHylfsa 235 D + k+ + ++ ++ ls+d s+ +l ++sa+ +iki+ l G++ + ++ + +s+ v+++ ++H ++a FUN_000562-T1 1053 WDLKRKIVVHQLVEPSSKVRCF---TLSMDKSKALTLgnsRFSASANvfhAEIKIFDLVSGEIIQWMLKYPSSIHLVQYIDSSHV-ITA 1137 7777777666666655554333...3455555544441112345554333689******************************96.699 PP Beta-prop_WDR3_2nd 236 gkdkkvkyWDad 247 ++dk ++ WD FUN_000562-T1 1138 SRDKIIRLWDLK 1149 **********65 PP == domain 3 score: 4.4 bits; conditional E-value: 0.05 Beta-prop_WDR3_2nd 45 afvpgdrhvlvgtkdGklevldlasaelletieah..egavwsvaltpdekglvtggaD.kkvkfwefelvee 114 +fv +++ +lv++ Gk++++dl+ +++ ++e ++ + + + + ++++v+ +D k++++++++ ++ FUN_000562-T1 1207 VFVDDNKAILVSC--GKMSLFDLNKNQMIVQFEGGiwDEGLANGCFIHTTHEVVAVNSDqKSLCVYDMHSGQR 1277 5555555555554..5666666666666655554333333333333333333333333314555555554332 PP == domain 4 score: 30.1 bits; conditional E-value: 7.1e-10 Beta-prop_WDR3_2nd 24 iwnvkslecirtiesey.alclafvpgdrhvlvgtkdGklevldlasaelletie.ahegavwsvaltpdekglvtg.....gaDkkvk 105 +++v++ + + +++y + +++++p+ rh+l+g+ dG +++ d++++++l++i+ ah g+v +++t+d++ +t+ ++D++++ FUN_000562-T1 1368 VFDVETGKLLFESATNYqVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRINrAHLGSVHRISTTDDGTVAMTTaggldSKDRSIR 1456 566777776666555541568899*****************************9659**************988875333445799*** PP Beta-prop_WDR3_2nd 106 fwefelv 112 fw+++ FUN_000562-T1 1457 FWNLDKD 1463 ***9854 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.2 1.1e-12 5.7e-10 6 192 .. 828 1022 .. 823 1032 .. 0.78 2 ! 10.3 0.1 0.00074 0.38 74 179 .. 1048 1152 .. 1031 1173 .. 0.54 3 ! 9.9 0.1 0.001 0.53 119 247 .. 1264 1401 .. 1248 1404 .. 0.69 4 ! 14.2 0.1 4.6e-05 0.024 77 245 .. 1318 1490 .. 1312 1494 .. 0.77 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 1.1e-12 EIF3I 6 lkGheRaltqikynreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletktavrs. 98 ++Gh+ ++t + + +G ll s+ d++ svw + G + t+eG v + ++ + +l+vt sa +++ W++++G+ + +++++ a+ + FUN_000562-T1 828 MSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVT-SAISSISAWRLSNGQRMFSVSQDHAIYAa 920 89********************************************************998887.67899****************99999862 PP EIF3I 99 ..vefsesgkllllvtdkv....mgkkseivvldirdeeeeee.eepvlkieveeskvtvalwsaldktiitghedgeiskydlktgeklksvk 185 + ++++++ l++ k ++ l+i+d++e++ +++++ +++e+++v a s+l +t +t +++++++yd+ + +++s++ FUN_000562-T1 921 piCLLEKEKRILMAAFIKSsiklYDLQAGSLALEIDDNSESDGiSSSLCLCTMEDQSVLYANTSNLATTTTTWVRQANLHTYDVLDIVQISSNQ 1014 214445555544443333300003344555567777776655426777888999999**************************98776665554 PP EIF3I 186 e.hekqit 192 + h +t FUN_000562-T1 1015 TvHFIGVT 1022 32555555 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00074 EIF3I 74 ntvklWdvetGkelktl.etktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghe 166 t++lWd++ ++++l e +++vr ++s++++++l+ +++ + +++++ +i+ + ++ e + + + s+++ +++ ++++it+++ FUN_000562-T1 1048 FTLELWDLKRKIVVHQLvEPSSKVRCFTLSMDKSKALTLGNSRFSASANVFHAEIKIFDLVS-GEIIQWMLKYPSSIHLVQYI-DSSHVITASR 1139 56666666666666553144556666666666666666666666666666666665544332.22222222233344444443.3344555666 PP EIF3I 167 dgeiskydlktge 179 d i +dlk++ FUN_000562-T1 1140 DKIIRLWDLKRSA 1152 6666666666554 PP == domain 3 score: 9.9 bits; conditional E-value: 0.001 EIF3I 119 kseivvldirdeeeeee..eepvlk.ieveeskvtvalwsaldktiitghedgeiskydlktgeklksvke..hekqitdlqlskdktylit.. 205 + +++v+d+++ +++++ e++ + +++ + + v +s+ ++ ++++ +s +++k+++ ++++++ e+ +++ql kd ++l FUN_000562-T1 1264 QKSLCVYDMHSGQRISQmkCEHIRRfVHTPNGDICVLGHSMINDEE-PAKSRYFLSVWNIKQRKRVRDIDQenVETDFNEMQLVKDGSLLSDiv 1356 4556666666555433210222222123334455555555555543.4556667999*******99987651257889********99875411 PP EIF3I 206 ...askDktaklldvetlevlktykterpvnsaaisplkdfvvlG 247 sk a ++dvet ++l + t+ v +++i p + +++lG FUN_000562-T1 1357 ydlQSKVYRAVVFDVETGKLLFESATNYQVHTSVILPETRHLLLG 1401 2225777788899*****************************998 PP == domain 4 score: 14.2 bits; conditional E-value: 4.6e-05 EIF3I 77 klWdvetGkelktl...etktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghed 167 +W++++ k ++ + +++t ++++ ++g+ll ++ + ++k + vv+d+++ + l + ++ +v++++ + ++++ g d FUN_000562-T1 1318 SVWNIKQRKRVRDIdqeNVETDFNEMQLVKDGSLLSDIVYDLQSKVYRAVVFDVETGKL-------LFESATNYQVHTSVILPETRHLLLGLFD 1404 67888887776655111456777888888888888888888888888888888866443.......3333445566677778899999****** PP EIF3I 168 geiskydlktgeklksvke.hekqitdlqlskdktylita.....skDktakll..dvetlevlktykterpvnsaaisplkdfvv 245 g+i+ d++tg++l+++++ h +++ + +++d t+ +t+ skD++ +++ d + +e+l ++ ++ v s is+ fv FUN_000562-T1 1405 GAIQLDDIDTGKCLHRINRaHLGSVHRISTTDDGTVAMTTaggldSKDRSIRFWnlDKDRMELLTVFTPDAKVSSMNISSDGFFVA 1490 ************99987543999************99986566668999999862267889***************9998877776 PP >> WHD_NWD1 NWD1-like, winged helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.1 0.0 5.1e-19 2.6e-16 13 123 .. 529 644 .. 524 646 .. 0.92 Alignments for each domain: == domain 1 score: 60.1 bits; conditional E-value: 5.1e-19 WHD_NWD1 13 nrslkggiegrleriEkelGklavqavakylvvsshGLtrlElyDllssdeellaelsvsi.....vfplllldsiiealGsllrevviderevyk 103 +++++g +++ +er+E ++G+l vq ++ y+++s+ GLt E+ Dlls+d+e+l+++ +p+ll +i + l l d v FUN_000562-T1 529 QSTVRGAVNALFERVEMQHGRLLVQHILAYITASKSGLTATEIEDLLSCDDEVLEDVYQYWtppirRIPPLLGVRIRNDLAGYLIDRGADGASVTT 624 6789999*************************************************97655566668899999******9999999999******* PP WHD_NWD1 104 lshlvllnilrrRYltstae 123 + h ++ ++r RYl++++e FUN_000562-T1 625 WYHRQFIEAARDRYLSTEEE 644 ***************99875 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.3 6.6e-10 3.4e-07 233 315 .. 825 908 .. 821 920 .. 0.90 2 ? -1.2 0.0 2.6 1.3e+03 249 274 .. 926 951 .. 913 972 .. 0.85 3 ? -0.2 0.1 1.2 6.5e+02 220 279 .. 1048 1117 .. 1025 1130 .. 0.72 4 ! 12.9 0.2 0.00013 0.07 170 275 .. 1132 1233 .. 1127 1237 .. 0.79 5 ? 1.0 0.1 0.56 2.9e+02 183 236 .. 1224 1281 .. 1205 1295 .. 0.62 6 ? 4.3 0.1 0.056 29 181 279 .. 1317 1422 .. 1313 1446 .. 0.75 7 ! 13.7 0.2 7.4e-05 0.038 184 304 .. 1369 1497 .. 1361 1518 .. 0.81 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 6.6e-10 Beta-prop_WDR36-Utp21_2nd 233 vRkfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvfl.vesaatslslsptgdfLatahvddlgvyLwsnktly 315 + ++sgh+ it l+ s+d++ l +a +Dst +wd++sg+l+ +f+ + + + +++s + +++t+ + +++ + sn + + FUN_000562-T1 825 IHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEgIGEDVCHVAISLDNSLVVTSAISSISAWRLSNGQRM 908 7789******************************************98999999*****************9999988886544 PP == domain 2 score: -1.2 bits; conditional E-value: 2.6 Beta-prop_WDR36-Utp21_2nd 249 spdarWlitasmDstirtwdlpsgkl 274 ++ r l++a + s+i+ +dl++g+l FUN_000562-T1 926 EKEKRILMAAFIKSSIKLYDLQAGSL 951 567899999999*********99987 PP == domain 3 score: -0.2 bits; conditional E-value: 1.2 Beta-prop_WDR36-Utp21_2nd 220 fsilvvDidtrrvvRkfsghknritDltfspd.........arWlitas.mDstirtwdlpsgkliDvfl 279 f++ + D++ + vv ++ + +++++ t+s d +r+ +a + i+++dl sg++i ++l FUN_000562-T1 1048 FTLELWDLKRKIVVHQLVEPSSKVRCFTLSMDkskaltlgnSRFSASANvFHAEIKIFDLVSGEIIQWML 1117 7888888888888999999999988888888732222221123333333235789999999999998764 PP == domain 4 score: 12.9 bits; conditional E-value: 0.00013 Beta-prop_WDR36-Utp21_2nd 170 qvvitagadkklkfwkfkskklletl.kleasisklvlhressllavalddfsilvvDidtrrvvRkfsghknritDltfsp 250 + vita++dk +++w++k+ +++ +l+++ +++ + + a++ ++++++vvD+++ + + +g k +i +f FUN_000562-T1 1132 SHVITASRDKIIRLWDLKRSAPPSAVeELKEEQAEVEIVGMYGHHAICWEKHALRVVDLQAGHFIHFVNGVKPQI---VFVD 1210 579****************9887776369999999999999999*******************999999999887...4666 PP Beta-prop_WDR36-Utp21_2nd 251 darWlitasmDstirtwdlpsgkli 275 d + ++ + + +dl++ ++i FUN_000562-T1 1211 DNKAILVSCGK--MSLFDLNKNQMI 1233 66655555433..334566555555 PP == domain 5 score: 1.0 bits; conditional E-value: 0.56 Beta-prop_WDR36-Utp21_2nd 183 fwkfkskklletlk...leas.isklvlhressllavalddfsilvvDidtrrvvRkf 236 ++++++++++ +++ +++ ++ + +h+ +++av d+ s++v+D+ + + + ++ FUN_000562-T1 1224 LFDLNKNQMIVQFEggiWDEGlANGCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQM 1281 4455554444443333344431344567888888888888888888888876655544 PP == domain 6 score: 4.3 bits; conditional E-value: 0.056 Beta-prop_WDR36-Utp21_2nd 181 lkfwkfkskklletlk...leasisklvlhressllavaldd.....fsilvvDidtrrvvRkfsghknritDltfspdarW 254 l +w++k++k ++ ++ +e+ ++++l ++ sll+ ++ d + +v+D++t ++ + + + +++ ++ p++r FUN_000562-T1 1317 LSVWNIKQRKRVRDIDqenVETDFNEMQLVKDGSLLSDIVYDlqskvYRAVVFDVETGKLLFESA-TNYQVHTSVILPETRH 1397 679****9999877653338889999*********985554412222567899******985543.344788888899**** PP Beta-prop_WDR36-Utp21_2nd 255 litasmDstirtwdlpsgkliDvfl 279 l+ D +i+ d+ +gk + + FUN_000562-T1 1398 LLLGLFDGAIQLDDIDTGKCLHRIN 1422 ***************9999876655 PP == domain 7 score: 13.7 bits; conditional E-value: 7.4e-05 Beta-prop_WDR36-Utp21_2nd 184 wkfkskklletlkleasisklvlhressllavalddfsilvvDidtrrvvRkf.sghknritDltfspdarWlita.....s 259 +++++ kll + + +++++v+ e+ l + l d +i++ Didt ++ ++ + h ++++ ++ d+ +t+ s FUN_000562-T1 1369 FDVETGKLLFESATNYQVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRInRAHLGSVHRISTTDDGTVAMTTaggldS 1450 56667777777777788888888888888888889999********99986652689************9987776355556 PP Beta-prop_WDR36-Utp21_2nd 260 mDstirtwdlpsg..kliDvflvesaatslslsptgdfLatahvddl 304 D +ir w+l + +l+ vf+ + + s+++s+ g f+a +d + FUN_000562-T1 1451 KDRSIRFWNLDKDrmELLTVFTPDAKVSSMNISSDGFFVALELTDVV 1497 899*******8751268*******************99998777665 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.1 1.6e-08 8.4e-06 47 192 .. 826 977 .. 821 1004 .. 0.80 2 ! 10.6 0.0 0.00055 0.29 75 136 .. 1100 1160 .. 1085 1175 .. 0.78 3 ? 4.3 0.1 0.048 25 142 209 .. 1205 1273 .. 1189 1303 .. 0.78 4 ! 11.7 1.1 0.00026 0.14 109 294 .. 1257 1461 .. 1247 1463 .. 0.65 5 ! 8.3 0.0 0.0029 1.5 68 115 .. 1398 1445 .. 1392 1490 .. 0.71 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.6e-08 WDR55 47 lslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWDlRkkkavmelke.hedyis 141 +s++ h+ + a++ s+dGk l s+ D +++v dv++g+l++++e e+ + +d+ l++t + W l + + ++++++ h y + FUN_000562-T1 826 HSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTSA-ISSISAWRLSNGQRMFSVSQdHAIYAA 920 67788999999****************************************************99986.6789*******9999998751555666 PP WDR55 142 dl.vvdeekklLlatsgdGtltvfnirkkklevqse.eyeee....llslalvkeek 192 + ++++ek++L+a+ +++ +++++ +l ++ + + e++ l+l+++++++ FUN_000562-T1 921 PIcLLEKEKRILMAAFIKSSIKLYDLQAGSLALEIDdNSESDgissSLCLCTMEDQS 977 6624588999*****************998776544122322111145555555555 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00055 WDR55 75 ksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWDlRkkkavmelkeh 136 i+++d+ +g++++ + k s+i+ +++id+ ++t+ d +++lWDl ++++ ++e FUN_000562-T1 1100 AEIKIFDLVSGEIIQWMLKY-PSSIHLVQYIDSSHVITASRDKIIRLWDLKRSAPPSAVEEL 1160 46899999999999988865.567**************************988654444433 PP == domain 3 score: 4.3 bits; conditional E-value: 0.048 WDR55 142 dlvvdeekklLlatsgdGtltvfnirkkklevqse..eyeeellslalvkeekkvvvG.sseGklylfnwg 209 ++v+ +++k +l+++g ++ f+++k+++ vq e +e l +++++ + vv+ s++ +l ++++ FUN_000562-T1 1205 QIVFVDDNKAILVSCG--KMSLFDLNKNQMIVQFEggIWDEGLANGCFIHTTHEVVAVnSDQKSLCVYDMH 1273 6788889999999997..89999999999999988434677777777777777666541555667777765 PP == domain 4 score: 11.7 bits; conditional E-value: 0.00026 WDR55 109 llatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLla...tsgdG.......tltvfnirkkk..levqseeyeeellslalvke 190 ++a d+ + ++D+ + + + ++k+ + i +v + + + + +d +l+v+ni+++k ++ e++e++++ ++lvk+ FUN_000562-T1 1257 VVAVNSDQKSLCVYDMHSGQRISQMKC--EHIRRFVHTPNGDICVLghsMINDEepaksryFLSVWNIKQRKrvRDIDQENVETDFNEMQLVKD 1348 555555666666666666666655554..345555555555544331111222244555558999999999854567889999**********9 PP WDR55 191 ekkv..vvGsseGkly...lfnwgefgahsdrfpghkesidclvpitenivvtgseDGiiRavhllPnrvlgvvGqheelpvekldiskdgkll 279 ++ + +v + + k+y +f+ ++ ++ ++ + + ++++p ++++ g DG i++ + ++l + + + +v +++ ++dg++ FUN_000562-T1 1349 GSLLsdIVYDLQSKVYravVFDVETGKLLFESATNYQVHTSVILPE-TRHLLLGLFDGAIQLDDIDTGKCLHRINRAHLGSVHRISTTDDGTVA 1441 9987334444444443222555555555555554444444444443.457789*********************999888*********99987 PP WDR55 280 ass.....shdqkvkFwnis 294 ++ s+d++++Fwn++ FUN_000562-T1 1442 MTTaggldSKDRSIRFWNLD 1461 665344447899*****986 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0029 WDR55 68 lfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdd 115 l+ D +i++ d++tgk++++i++ah +++ +++ d+ ++a FUN_000562-T1 1398 LLLGLFDGAIQLDDIDTGKCLHRINRAHLGSVHRISTTDDGTVAMTTA 1445 555666889999999999999999999999999999999888775433 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.2 2.5e-06 0.0013 129 218 .. 826 911 .. 818 920 .. 0.59 2 ? 1.7 0.1 0.34 1.8e+02 29 92 .. 895 958 .. 872 1020 .. 0.51 3 ! 9.3 0.1 0.0017 0.89 75 180 .. 1050 1167 .. 978 1188 .. 0.66 4 ? 2.5 0.1 0.2 1e+02 62 105 .. 1254 1297 .. 1246 1306 .. 0.76 5 ! 17.5 0.0 5.5e-06 0.0028 27 151 .. 1359 1490 .. 1331 1495 .. 0.75 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 2.5e-06 WD40_CDC20-Fz 129 ktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksv 218 +++++h+ ++ l+ s+dg+llAs d+t+++wd++s + + +++ v +a + +sl++t +i w+ ++g+ + sv FUN_000562-T1 826 HSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLD-NSLVVTSAI---SSISAWRLSNGQRMFSV 911 456677777777777777777777777777777777766666666655555555554442.333333332...34555555555555555 PP == domain 2 score: 1.7 bits; conditional E-value: 0.34 WD40_CDC20-Fz 29 ssvylwnaetgevkelldlseesdyv.tsvkws.edgelLavGtssgevelwdvekkkklrtlegh 92 ss+ w+ ++g+ +++++s+++ ++ ++ +++++L+ + +++++l+d ++++ +++ + FUN_000562-T1 895 SSISAWRLSNGQ--RMFSVSQDHAIYaAPICLLeKEKRILMAAFIKSSIKLYDLQAGSLALEIDDN 958 233333333332..2233333222220222222133445555555555555555555544444433 PP == domain 3 score: 9.3 bits; conditional E-value: 0.0017 WD40_CDC20-Fz 75 velwdvekkkklrtleghssrvgalaw...nenllssG....srdgkilhhDvrtkelevvktlkahkqevcg..lkwspdgrllAsGgndntv 159 +elwd ++k +++l + ss+v +++ +++ l+ G s + +++h ++++ +l + ++++ + ++ l d++++ + + d+ + FUN_000562-T1 1050 LELWDLKRKIVVHQLVEPSSKVRCFTLsmdKSKALTLGnsrfSASANVFHAEIKIFDLVSGEIIQWMLKYPSSihLVQYIDSSHVITASRDKII 1143 5666666666666666666666555443333445666633333455566666666654443333322222222002223355666666666666 PP WD40_CDC20-Fz 160 kiwdlrslsp...llkltehkaav 180 ++wdl+ ++p + +l+e +a v FUN_000562-T1 1144 RLWDLKRSAPpsaVEELKEEQAEV 1167 666666554322244555555554 PP == domain 4 score: 2.5 bits; conditional E-value: 0.2 WD40_CDC20-Fz 62 dgelLavGtssgevelwdvekkkklrtleghssrvgalawnenl 105 + e++av +++ ++ ++d+++++++++++ ++ r + + n+++ FUN_000562-T1 1254 THEVVAVNSDQKSLCVYDMHSGQRISQMKCEHIRRFVHTPNGDI 1297 56789999999999999999999999999877666555555555 PP == domain 5 score: 17.5 bits; conditional E-value: 5.5e-06 WD40_CDC20-Fz 27 lgssvylwnaetge.vkelldlseesdyvtsvkwsedgelLavGtssgevelwdvekkkklrtle.ghssrvgalawnenl....lssG...sr 111 l+s+vy + e k l++ +++ ++ tsv +++++L +G +g ++l d+ ++k+l++++ +h +v+ ++ +++ ++G s+ FUN_000562-T1 1359 LQSKVYRAVVFDVEtGKLLFESATNYQVHTSVIL-PETRHLLLGLFDGAIQLDDIDTGKCLHRINrAHLGSVHRISTTDDGtvamTTAGgldSK 1451 6666665544333303445676666677777765.5578899*******************999736889999999976543342344467789 PP WD40_CDC20-Fz 112 dgkilhhDvrtkelevvktlkahkqevcglkwspdgrllA 151 d++i+++++ + ++e t+ +v+++++s+dg ++A FUN_000562-T1 1452 DRSIRFWNLDKDRMEL-LTVFTPDAKVSSMNISSDGFFVA 1490 99********999986.567788999*******9998877 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 9e-06 0.0047 70 164 .. 821 913 .. 812 930 .. 0.85 2 ? -2.0 0.0 5.1 2.6e+03 21 52 .. 1049 1081 .. 1040 1090 .. 0.80 3 ! 12.7 0.2 0.00016 0.084 11 162 .. 1132 1281 .. 1125 1292 .. 0.80 4 ? 3.9 0.1 0.076 40 6 58 .. 1251 1302 .. 1242 1366 .. 0.64 5 ! 11.0 0.0 0.00053 0.27 23 147 .. 1367 1497 .. 1360 1524 .. 0.74 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 9e-06 Beta-prop_EML_2 70 tleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskkykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkqvtsas 163 + +++++ ++ +i++++ s dgklLa + d++ ++dv ++ + v++++g + + h+ s d++++ + s+ +++ w++++g+++ s s FUN_000562-T1 821 GGPLIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDV-NSGRLVRTFEGIGEDVCHVAISLDNSLVVT-SAISSISAWRLSNGQRMFSVS 912 55567888889999**************************9.67899*******************998765.589999********9987765 PP Beta-prop_EML_2 164 a 164 + FUN_000562-T1 913 Q 913 4 PP == domain 2 score: -2.0 bits; conditional E-value: 5.1 Beta-prop_EML_2 21 tvrlWdlekkklvak.vklekearsvafspdgk 52 t+ lWdl++k +v++ v+ ++++r+ ++s d++ FUN_000562-T1 1049 TLELWDLKRKIVVHQlVEPSSKVRCFTLSMDKS 1081 678999999988876258889999999998875 PP == domain 3 score: 12.7 bits; conditional E-value: 0.00016 Beta-prop_EML_2 11 pqfvTagdDktvrlWdlekkklvakv.klekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgsh 101 ++++Ta+ Dk++rlWdl++ + v +l++e v++ + a+ ++ + v+d + + ++ v+ k + i f +d+k + v++ FUN_000562-T1 1132 SHVITASRDKIIRLWDLKRSAPPSAVeELKEEQAEVEIVGMYGHHAICWEKHALRVVDLQAGHFIHFVNGVKPQ---IVFVDDNKAILVSC- 1219 6799*************98766555438999999999999999999999**99999998888888877777665...67889999999999. PP Beta-prop_EML_2 102 dnkiylYdvskkykkvgklkgh...ssfithlDwsedskylqsnsgdyellfwdaktgkqvtsa 162 +k+ l+d++k+ + + +++g + + ++ +++ +ns++ +l+++d+++g+++++ FUN_000562-T1 1220 -GKMSLFDLNKN-QMIVQFEGGiwdEGLANGCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQM 1281 .89999998654.44445554322155667777788999*******************999875 PP == domain 4 score: 3.9 bits; conditional E-value: 0.076 Beta-prop_EML_2 6 thpsepqfvTagdDktvrlWdlekkklvakvklekearsvafspdgkllavGl 58 +h ++++++ +d k+++++d+++ + + ++k+e+ +r p+g+++++G FUN_000562-T1 1251 IHTTHEVVAVNSDQKSLCVYDMHSGQRISQMKCEH-IRRFVHTPNGDICVLGH 1302 56666666777777777777777777777777764.44445566777766665 PP == domain 5 score: 11.0 bits; conditional E-value: 0.00053 Beta-prop_EML_2 23 rlWdlekkklvakvklekearsvafspdgkllavGlkdGsvlvldaetleevvevkd.rkeaisdikfspdgklLavg.....shdnkiylY 108 +++d+e+ kl+ ++ +++++++ + p+ ++l +Gl dG + + d +t++ +++++ + +++ i+ +dg++ s+d +i ++ FUN_000562-T1 1367 VVFDVETGKLLFESATNYQVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRINRaHLGSVHRISTTDDGTVAMTTaggldSKDRSIRFW 1458 57888899999999999999999999999999999999999999999999999886624578889998888865433223677889999999 PP Beta-prop_EML_2 109 dvskkykkvgklkghssfithlDwsedskylqsnsgdye 147 +++k+ ++ ++ + + ++ s+d+ ++ + +d+ FUN_000562-T1 1459 NLDKDRMELLTVFTPDAKVSSMNISSDGFFVALELTDVV 1497 998876666666677888888888888888877666655 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.2 9.9e-08 5.1e-05 2 39 .] 823 860 .. 822 860 .. 0.94 2 ? 5.9 0.1 0.059 31 1 29 [. 864 892 .. 864 901 .. 0.89 3 ! 11.9 0.1 0.00074 0.39 22 39 .] 1130 1147 .. 1122 1147 .. 0.93 4 ! 10.6 0.3 0.0018 0.96 1 39 [] 1415 1459 .. 1415 1459 .. 0.84 5 ? -0.5 0.0 6.1 3.2e+03 5 27 .. 1469 1490 .. 1465 1490 .. 0.73 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 9.9e-08 WD40 2 kllrtlkgHtsgVtslafspdgsllasg.sdDgtvklWd 39 l+++++gH+ ++t+l+ s dg+llas+ D+t+ +Wd FUN_000562-T1 823 PLIHSMSGHQLPITALSSSADGKLLASApV-DSTCSVWD 860 5799*****999***************988.*******9 PP == domain 2 score: 5.9 bits; conditional E-value: 0.059 WD40 1 gkllrtlkgHtsgVtslafspdgsllasg 29 g+l+rt++g ++V+ +a+s d+sl++++ FUN_000562-T1 864 GRLVRTFEGIGEDVCHVAISLDNSLVVTS 892 57899****9888*************997 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00074 WD40 22 dgsllasgsdDgtvklWd 39 d+s+++++s+D+ ++lWd FUN_000562-T1 1130 DSSHVITASRDKIIRLWD 1147 88999************9 PP == domain 4 score: 10.6 bits; conditional E-value: 0.0018 WD40 1 gkllrtl.kgHtsgVtslafspdgsllasg.....sdDgtvklWd 39 gk+l+ + ++H ++V ++ +dg+ + s+D+++++W+ FUN_000562-T1 1415 GKCLHRInRAHLGSVHRISTTDDGTVAMTTaggldSKDRSIRFWN 1459 6788887479*999************7644368999********7 PP == domain 5 score: -0.5 bits; conditional E-value: 6.1 WD40 5 rtlkgHtsgVtslafspdgslla 27 ++++ + V+s+ +s+dg ++a FUN_000562-T1 1469 TVFTPD-AKVSSMNISSDGFFVA 1490 555433.66**********8875 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 3.7e-05 0.019 35 77 .. 829 871 .. 822 883 .. 0.88 2 ! 8.3 0.0 0.0074 3.9 14 81 .. 892 960 .. 886 975 .. 0.76 3 ? 0.7 0.0 1.8 9.2e+02 3 76 .. 1119 1199 .. 1117 1210 .. 0.64 4 ? -1.8 0.0 9.9 5.2e+03 54 77 .. 1214 1237 .. 1200 1241 .. 0.80 5 ? 1.3 0.0 1.1 5.8e+02 50 80 .. 1255 1285 .. 1214 1304 .. 0.63 6 ? 4.7 0.0 0.095 50 49 78 .. 1394 1423 .. 1379 1433 .. 0.87 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 3.7e-05 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgklvhsls 77 +++++ +t+l+ + dGklLa a d+++++ dv+sg+lv++++ FUN_000562-T1 829 SGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFE 871 678999*********************************9997 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0074 ANAPC4_WD40 14 tedgevllkRl.nwqrvwklseekedsevtsla.WkpdGklLavaysdgevrlldvesgklvhslsaksd 81 ++ +++ + Rl n+qr +++s+++ + ++ +++ ++L+ a+ +++++l+d + g l+ +++ +s+ FUN_000562-T1 892 SAISSISAWRLsNGQRMFSVSQDHA-IYAAPIClLEKEKRILMAAFIKSSIKLYDLQAGSLALEIDDNSE 960 55578889999899******55444.4444555156666789999***************9998887766 PP == domain 3 score: 0.7 bits; conditional E-value: 1.8 ANAPC4_WD40 3 wcpkmDLiAlatedgevllkRlnwqrvwklseekedsevtslaWkpdGklL.......avaysdgevrlldvesgklvhsl 76 + ++ L+ ++ ++ + ++R + r+w+l++++ s+v++l+ ++ + + a+ +++ +r++d + g+ +h + FUN_000562-T1 1119 YPSSIHLVQYIDSSHVITASRDKIIRLWDLKRSAPPSAVEELKEEQAEVEIvgmyghhAICWEKHALRVVDLQAGHFIHFV 1199 556667777777888888999999999999888888888877755544333122222245566666666666666666655 PP == domain 4 score: -1.8 bits; conditional E-value: 9.9 ANAPC4_WD40 54 avaysdgevrlldvesgklvhsls 77 a+ +s g+++l+d ++ +++ +++ FUN_000562-T1 1214 AILVSCGKMSLFDLNKNQMIVQFE 1237 4455669999******99999885 PP == domain 5 score: 1.3 bits; conditional E-value: 1.1 ANAPC4_WD40 50 GklLavaysdgevrlldvesgklvhslsaks 80 ++ av ++ ++ ++d++sg+ ++++++++ FUN_000562-T1 1255 HEVVAVNSDQKSLCVYDMHSGQRISQMKCEH 1285 3444555555555555555555555555543 PP == domain 6 score: 4.7 bits; conditional E-value: 0.095 ANAPC4_WD40 49 dGklLavaysdgevrlldvesgklvhslsa 78 + + L + dg ++l d+ +gk++h ++ FUN_000562-T1 1394 ETRHLLLGLFDGAIQLDDIDTGKCLHRINR 1423 56789999******************9875 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.1 0.0 5.9e-12 3.1e-09 1 152 [. 328 457 .. 328 475 .. 0.72 Alignments for each domain: == domain 1 score: 38.1 bits; conditional E-value: 5.9e-12 AAA_16 1 klvgReeeleaLlallervrsgrpplvlvsGeaGvGKSalvrellr...aleraalvlsgkcdelqrglpy......aallealtresllrqllae 87 +++gR e l++ +a+l++ r+ + ++++G++G GK+++++ +++ +s++ + y + +++l+r s+++q+++ FUN_000562-T1 328 TFYGRNEILDQCRAYLKDDRQ---NPLVIYGQSGCGKTSVMSMIAKeawN-------ISSQSNVV---IRYigttpnSSQIRLLLR-SVCEQICSI 409 59**************97766...5799*************999962222.......22222222...233332111556666645.777777755 PP AAA_16 88 seaallaawraalleelaavpalegeeaerllealsrllalaarkerplvlvlDdlqwadeasld 152 ++ ++ + +e++ l+e + ++l+la++ e+pl +++D l+++ +++ + FUN_000562-T1 410 -----YGQNPHTIRKEIK-----------ELHEDFMSCLQLAKE-EEPLFIFFDSLDQFGPEDNA 457 .....5566666777777...........9*********99999.999*********99877655 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.3 3e-08 1.5e-05 153 262 .. 842 953 .. 822 981 .. 0.62 2 ? 3.9 0.0 0.06 31 203 256 .. 1097 1149 .. 1042 1153 .. 0.72 3 ? -0.7 0.1 1.4 7.5e+02 150 185 .. 1207 1241 .. 1190 1302 .. 0.66 4 ! 8.2 0.1 0.0029 1.5 166 267 .. 1366 1474 .. 1318 1493 .. 0.78 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 3e-08 WD40_Gbeta 153 ddnqivtss.gdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtf.ighesdinaiaffpngeal.atgs 245 d ++++s+ d+tc++wd+++g+ +f g dv ++++ d l+v+ a +s+ w + +g ++ h i+++ + + + ++ FUN_000562-T1 842 ADGKLLASApVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTSAI-SSISAWRLSNGQRMFSVsQDHAIYAAPICLLEKEKRIlMAAF 936 34444444325777888888888877788887778888888877777777665.567777777765433330233334444777766554414445 PP WD40_Gbeta 246 ddatcrlfdlradqell 262 ++ +l+dl+a l FUN_000562-T1 937 IKSSIKLYDLQAGSLAL 953 56777777777765555 PP == domain 2 score: 3.9 bits; conditional E-value: 0.06 WD40_Gbeta 203 acdasaklwdvreglcrqtfighesdinaiaffpngealatgsddatcrlfdlr 256 a +k++d+ g q ++ + s i + ++ + + t s d rl+dl+ FUN_000562-T1 1097 VFHAEIKIFDLVSGEIIQWMLKYPSSIHLVQYIDSSH-VITASRDKIIRLWDLK 1149 3568888999999999999999999998888776655.5567788888998886 PP == domain 3 score: -0.7 bits; conditional E-value: 1.4 WD40_Gbeta 150 rflddnqivtssgdttcalwdietgqqttvfvghtg 185 f+ddn+ + s +l+d++ q + f g FUN_000562-T1 1207 VFVDDNKAILVSCG-KMSLFDLNKNQMIVQFEGGIW 1241 57777775544433.346788888877777776543 PP == domain 4 score: 8.2 bits; conditional E-value: 0.0029 WD40_Gbeta 166 calwdietgqqttvfvghtg.dvmslslapdtrlfvsgacdasaklwdvreglcrqtf.ighesdinaiaffpnge.alat.g...sddatcrl 252 + ++d+etg+ f t +v + + p+tr ++ g d +++l d+ g c + + h + i+ +g+ a++t g s d + r+ FUN_000562-T1 1366 AVVFDVETGKLL--FESATNyQVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRInRAHLGSVHRISTTDDGTvAMTTaGgldSKDRSIRF 1457 568999999754..444443156666778*************************7655268999*******99997355554234478999*** PP WD40_Gbeta 253 fdlradq.ellv.yshd 267 ++l d+ ell+ ++ d FUN_000562-T1 1458 WNLDKDRmELLTvFTPD 1474 **999863665415544 PP >> Beta-prop_NWD2_C NWD2 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 1.4e-07 7.1e-05 1 108 [. 825 934 .. 825 948 .. 0.84 2 ? 2.3 0.9 0.21 1.1e+02 25 223 .. 935 1143 .. 922 1151 .. 0.62 3 ! 10.5 0.0 0.00063 0.33 23 200 .. 1214 1395 .. 1194 1490 .. 0.72 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 1.4e-07 Beta-prop_NWD2_C 1 Vhvidrlelqidsislaeeael.avtvtRncvgvWdletgkLlkkladsslgaivthavitkdgkyvvsaesgkvliwelekeqvlfkeeqkd 92 +h++ ++l+i ++s + + +l a + ++ +vWd+++g+L+++++ g v h +i+ d + vv++ +++ w+l++ q +f+ +q + FUN_000562-T1 825 IHSMSGHQLPITALSSSADGKLlASAPVDSTCSVWDVNSGRLVRTFEG--IGEDVCHVAISLDNSLVVTSAISSISAWRLSNGQRMFSVSQDH 915 689999********999988761556678899**************99..78889*****************************999988765 PP Beta-prop_NWD2_C 93 v...kqlllleddtkviav 108 + lle+++++++ FUN_000562-T1 916 AiyaAPICLLEKEKRILMA 934 3122568888888887765 PP == domain 2 score: 2.3 bits; conditional E-value: 0.21 Beta-prop_NWD2_C 25 tvtRncvgvWdletgkLlkkladsslgaivtha..vitkdgkyvvsaesgkvliwel..ekeqvlfkeeqkdvkqlllleddtkviavske 111 + ++++ ++dl+ g L ++ d+s + ++++ + t + + v+ a+++++ + ++ l + + d+ q+ + + ++i v+k FUN_000562-T1 935 AFIKSSIKLYDLQAGSLALEIDDNSESDGISSSlcLCTMEDQSVLYANTSNLATTTTtwVRQANLHTYDVLDIVQISSN-QTVHFIGVTKM 1024 5567888999999999999999998887776652256889999999999887654330034444444455555555433.33455666666 PP Beta-prop_NWD2_C 112 kea...ekkakvvvrsiPegekvyefey.evkk..kfkkavltadglflvvlavdksekdvllvynaktGtllekiklkyenikdvsalva 196 +++ ++++ + + + ++ +++e +k +++ v + ++ l++dks+ +l + + + + ++k ++ + + FUN_000562-T1 1025 NQMllaLTEGSPNTKKESSVQTFFTLELwDLKRkiVVHQLVEPSSKVRCFTLSMDKSKALTLGNSRFSASANVFHAEIKIFDLVSGEIIQW 1115 6556665555666666666777777764123323356778888888889999999997777766666666666667777766666555555 PP Beta-prop_NWD2_C 197 lphkanqvalide.dkgnilDikkkklv 223 + + ++ + l++ d ++++ + k++ FUN_000562-T1 1116 MLKYPSSIHLVQYiDSSHVITASRDKII 1143 5555555555542245556655555555 PP == domain 3 score: 10.5 bits; conditional E-value: 0.00063 Beta-prop_NWD2_C 23 avtvtRncvgvWdletgkLlkkladsslgaivthavitkdgkyv..vsaesgkvliwelekeqvlfkeeqkdvkqlllleddtkviavske 111 a+ v+ + ++++dl++ +++ +++ + + + + ++ v v ++ +++ ++++++ q +++ +++++++ + + +++ ++ + FUN_000562-T1 1214 AILVSCGKMSLFDLNKNQMIVQFEGGIWDEGLANGCFIHTTHEVvaVNSDQKSLCVYDMHSGQRISQMKCEHIRRFVHTPNGDICVLGHSM 1304 6666666677777777777777777666555555555555555501455667899********************9999998888754333 PP Beta-prop_NWD2_C 112 .kea...ekkakvvvrsiPegekvyefey.evkkkfkkavltadglflvvlavdksekdv.llvynaktGtllekiklkyenikdvsalva 196 + + +++ + v +i + ++v +++ +v+++f+++ l +dg+ l + +d ++k + +v++++tG+ll + +y+ + v FUN_000562-T1 1305 iNDEepaKSRYFLSVWNIKQRKRVRDIDQeNVETDFNEMQLVKDGSLLSDIVYDLQSKVYrAVVFDVETGKLLFESATNYQVHT----SVI 1391 12223347888899999*******99997256779*************9998888765432679*******9998877766333....333 PP Beta-prop_NWD2_C 197 lphk 200 lp+ FUN_000562-T1 1392 LPET 1395 3433 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 0.1 2.5e-10 1.3e-07 13 146 .. 340 461 .. 291 477 .. 0.76 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 2.5e-10 NPHP3_N 13 qeWldspsdssllwlsGkpGsGKsvlastvidhlqa..egsavayfffdfsdeekqslssllrsllhqlasqlpelreelleklaedlgldekdlr 106 ++ l++++ ++ l ++G+ G+GK+ ++s+++++ + ++s+v++ ++ + +++++++ llrs++ q++s + ++ + ++++ FUN_000562-T1 340 RAYLKDDR-QNPLVIYGQSGCGKTSVMSMIAKEAWNisSQSNVVIRYIG-TTPNSSQIRLLLRSVCEQICSIYGQNPHTIRKEIK----------- 422 55666554.56799*****************997542144555555554.6778889*************998888777766554........... PP NPHP3_N 107 elweklletlllakslsrpvyiviDALDEceeseellell 146 el e++++ l+ +++++p++i+ D LD +++ +l+ FUN_000562-T1 423 ELHEDFMSCLQ-LAKEEEPLFIFFDSLDQFGPEDNARQLI 461 45555555554.556789**********995554433333 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.1 0.0 2.4e-10 1.3e-07 2 138 .. 350 491 .. 349 512 .. 0.76 Alignments for each domain: == domain 1 score: 32.1 bits; conditional E-value: 2.4e-10 NACHT 2 tvilqGeaGsGKTtLlqklalawaegklpqdafklvFflslrelsrsgka....lsladllfsqlpepaapvse..........viavllelperl 83 ++++ G++G+GKT + +a ++++ +++ v +++++ s+++ +s++++++s + + ++++ l++ +e l FUN_000562-T1 350 PLVIYGQSGCGKTSVMSMIAKEAWNISSQSN----VVIRYIGTTPNSSQIrlllRSVCEQICSIYGQNPHTIRKeikelhedfmSCLQLAKEEEPL 441 579*****************99988885553....55555666666666666789******************96777777643333334444444 PP NACHT 84 LlilDGlDelksqlgqpkekqpvrtlLssllrkkllpeasllltvrpdalrk....lre 138 + +D+lD++ ++++ r+l+ +++ l+ ++l++++ pd+ + l++ FUN_000562-T1 442 FIFFDSLDQFGPEDNA-------RQLI--WFPSVLPNHVKLVVSTLPDNEYEcfpiLQK 491 4668*******98888.......9999..******************998774444343 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.5 8.8e-08 4.6e-05 85 179 .. 827 917 .. 814 967 .. 0.86 2 ? 5.7 0.0 0.019 9.9 160 205 .. 1103 1149 .. 1088 1181 .. 0.76 3 ? 1.9 0.2 0.28 1.4e+02 149 204 .. 1215 1272 .. 1207 1287 .. 0.48 4 ? 1.3 0.0 0.42 2.2e+02 155 201 .. 1403 1450 .. 1388 1483 .. 0.69 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 8.8e-08 Beta-prop_TEP1_2nd 85 vlrghtgavtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkddllvscssdGsvglWdiekeqrlgkflG 175 + gh+ ++t s s dG+lla++ d + +Wdv+ l+r++ d v a d+ lv +s+ s++ W ++++qr+ FUN_000562-T1 827 SMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNS---GRLVRTFEGIGED-VCHVAISLDNSLVVTSAISSISAWRLSNGQRMFSVSQ 913 678********************************88...789*******999.67788888999999*****************987765 PP Beta-prop_TEP1_2nd 176 hqsa 179 ++ FUN_000562-T1 914 DHAI 917 5544 PP == domain 2 score: 5.7 bits; conditional E-value: 0.019 Beta-prop_TEP1_2nd 160 glWdiekeqrlgkflGhqsavsavvave.ehvvsvgrdGllkvWdlq 205 ++d+ +++ ++ +l + s++ v ++ hv++ +rd +++ Wdl+ FUN_000562-T1 1103 KIFDLVSGEIIQWMLKYPSSIHLVQYIDsSHVITASRDKIIRLWDLK 1149 56666677777777777777777766542577777777777777764 PP == domain 3 score: 1.9 bits; conditional E-value: 0.28 Beta-prop_TEP1_2nd 149 llvscssdGsvglWdiekeqrlgkflGh..qs..avsavvaveehvvsvgrdG.llkvWdl 204 +lvsc G ++l+d++k+q +++f G + a + + + vv+v+ d +l v+d+ FUN_000562-T1 1215 ILVSC---GKMSLFDLNKNQMIVQFEGGiwDEglANGCFIHTTHEVVAVNSDQkSLCVYDM 1272 55555...56677777777777777663112211222222333334444444214555543 PP == domain 4 score: 1.3 bits; conditional E-value: 0.42 Beta-prop_TEP1_2nd 155 sdGsvglWdiekeqrlgkfl.GhqsavsavvaveehvvsvgrdGllkv 201 dG++ l di++++ l++ h +v + + ++ v+++ G l FUN_000562-T1 1403 FDGAIQLDDIDTGKCLHRINrAHLGSVHRISTTDDGTVAMTTAGGLDS 1450 577777777777777777642577777777777777777766655543 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 5.5 2.8e+03 181 210 .. 409 438 .. 407 441 .. 0.87 2 ! 15.1 0.1 3.3e-05 0.017 66 176 .. 835 938 .. 825 1035 .. 0.66 3 ? 1.7 0.0 0.41 2.1e+02 10 101 .. 1069 1153 .. 1064 1179 .. 0.75 4 ? 1.0 0.0 0.65 3.4e+02 87 133 .. 1181 1224 .. 1138 1242 .. 0.78 5 ? 1.3 0.0 0.52 2.7e+02 81 109 .. 1258 1285 .. 1241 1292 .. 0.82 6 ? 4.5 0.0 0.055 29 17 110 .. 1291 1385 .. 1284 1402 .. 0.80 7 ! 9.1 0.1 0.0021 1.1 144 230 .. 1372 1463 .. 1311 1486 .. 0.74 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 5.5 Beta-prop_EML 181 vWskgtnkiskavkkahegsvfsllvlkdg 210 +++++ ++i k++k+ he ++l++ k++ FUN_000562-T1 409 IYGQNPHTIRKEIKELHEDFMSCLQLAKEE 438 78889999***************9998875 PP == domain 2 score: 15.1 bits; conditional E-value: 3.3e-05 Beta-prop_EML 66 vsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhiaFWtlegkklekkkgifeksekpkyvlc 161 +++l s++++gklLa+ + ++ svWd+++g+++ + ++ + v++v+++ d++l+vt + i+ W+l++++ + ++++ +c FUN_000562-T1 835 ITAL--SSSADGKLLASAPVD--STCSVWDVNSGRLVRTFEGIGEDVCHVAISL-DNSLVVTSAISSISAWRLSNGQRM--FSVSQDHAIYAAPIC 923 5555..455689999987655..599************************9975.899***************976522..222333333333444 PP Beta-prop_EML 162 lafsengdvitGdsn 176 l +e+ ++++ + FUN_000562-T1 924 LLEKEKRILMAAFIK 938 444444444444444 PP == domain 3 score: 1.7 bits; conditional E-value: 0.41 Beta-prop_EML 10 ddikclavhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgek 101 ++++c+++ +k t ++ s++++ ++ i+i d ++ e ++ + ++ +++ +++ ++ ++ s+++++ +Wd +++ FUN_000562-T1 1069 SKVRCFTLSMDKSKALTLGNSRFSASANVFHAEIKIFDLVSGEIIQWML--KYPSSIHLVQYIDSS-----HVITASRDKIIRLWDLKRSAP 1153 5788999998888888866666677777789999999999999999874..478999999999665.....5889999999****9998843 PP == domain 4 score: 1.0 bits; conditional E-value: 0.65 Beta-prop_EML 87 nehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhi 133 ++h l v d q g+ + +++ k +++ v+ +k +lv+cGk + FUN_000562-T1 1181 EKHALRVVDLQAGHFIHFVNGVKPQIVFVD---DNKAILVSCGKMSL 1224 579999999999999999999999988775...56689*****9876 PP == domain 5 score: 1.3 bits; conditional E-value: 0.52 Beta-prop_EML 81 aavdesnehvlsvWdwqkgeklaetktsk 109 +av +s++++l+v+d+++g++++++k+++ FUN_000562-T1 1258 VAV-NSDQKSLCVYDMHSGQRISQMKCEH 1285 444.56779****************9975 PP == domain 6 score: 4.5 bits; conditional E-value: 0.055 Beta-prop_EML 17 vhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaav..d.esnehvlsvWdwqkgeklaetkt 107 pn+++++ G+ ++++ +++ +W++++ + ++ ++++++e ++ k +g+lL + d +s+ +v+d+++g++l e+ t FUN_000562-T1 1291 HTPNGDICVLGHSMINDEEPAKSRYFLSVWNIKQRKRVRDIDQENVETDFNEMQLVK--DGSLLSDIvyDlQSKVYRAVVFDVETGKLLFESAT 1382 459999999999999999999999*******************************96..68899765224233445788*******99999877 PP Beta-prop_EML 108 skd 110 + + FUN_000562-T1 1383 NYQ 1385 654 PP == domain 7 score: 9.1 bits; conditional E-value: 0.0021 Beta-prop_EML 144 ekkkgifeksekpkyvlclafsengdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsg..gg...kdgkivawdanle 230 e+ k +fe+ ++ ++ +++ e+ +++ G +G i + + +t k+ + +++ah gsv + +++dgt+ ++ gg kd++i w+ + + FUN_000562-T1 1372 ETGKLLFESATNYQVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRINRAHLGSVHRISTTDDGTVAMTtaGGldsKDRSIRFWNLDKD 1463 5566789999999999999999999******************************************9865422432226666766665444 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.6 1e-07 5.3e-05 86 226 .. 832 965 .. 818 993 .. 0.78 2 ? 2.7 0.4 0.16 81 88 231 .. 876 1011 .. 873 1028 .. 0.68 3 ! 6.7 0.2 0.0096 5 13 166 .. 1128 1281 .. 1076 1300 .. 0.49 4 ? 1.1 0.2 0.48 2.5e+02 236 264 .. 1257 1285 .. 1176 1343 .. 0.80 5 ? -1.3 0.0 2.6 1.4e+03 142 142 .. 1440 1440 .. 1368 1495 .. 0.51 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 1e-07 WD40_WDHD1_1st 86 tapvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlpksndfsasks 180 ++p+t+++ s+dgklla++ D t v +v+ + + t+eg + v va++ + l+ +s ++ W +++++ + +++ + + + FUN_000562-T1 832 QLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDN-SLVVTSAISSISAWRLSNGQRMFSVS----QDHAIYAAP 921 68999*************************9999999*************99555.55666666799******999885533....344555666 PP WD40_WDHD1_1st 181 lcrlawepksgkllavP.vekevklyerdtweeafklsknklsedis 226 +c l+ k++++l+ + ++ ++kly+ + + a ++++n+ s+ is FUN_000562-T1 922 ICLLE---KEKRILMAAfIKSSIKLYDLQAGSLALEIDDNSESDGIS 965 77776...335555555366688888888888888888777776665 PP == domain 2 score: 2.7 bits; conditional E-value: 0.16 WD40_WDHD1_1st 88 pvthialskdgkllaagseDftikvvsvedsskqktle.ghkapvlsval.dpkgeylaSsscDGtvkiWdieskecvktlkvlpksndfsas 178 +v h+a+s d++l+ + s+ +i ++++++ ++++ +h ++l + ++ +l+++ + ++k++d++ ++ + +++ ++s +s+s FUN_000562-T1 876 DVCHVAISLDNSLV-VTSAISSISAWRLSNGQRMFSVSqDHAIYAAPICLlEKEKRILMAAFIKSSIKLYDLQAGSLALEIDDNSESDGISSS 967 68899998887655.555667889999988888887763666666666651455578899999999999999999999999999999999999 PP WD40_WDHD1_1st 179 kslcrlawepksgkllavPvekevklyerdtweeafklsknklsedisivafS 231 lc+++ +++l +++ + +++tw ++ +l++ ++ + iv++S FUN_000562-T1 968 LCLCTMED----QSVL-YANTSNLA-TTTTTWVRQANLHTYDV---LDIVQIS 1011 99999873....3334.44444433.34555666666654333...3444444 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0096 WD40_WDHD1_1st 13 ysedgkkliTcGsDgdvriwegledddpksi.kvgekataiavks..dklvvatddntvqlytfpegekdgiltrftapvthialskdgklla 102 y d +++iT+ +D +r+w+ + p+ + +++e+ + + + ++ ++ +++++++++++ g + + ++ ++ ++ +++ +l+ FUN_000562-T1 1128 YI-DSSHVITASRDKIIRLWDLKRSAPPSAVeELKEEQAEVEIVGmyGHHAICWEKHALRVVDLQAGHFIHFVNGVKPQIVFVD--DNKAILV 1217 33.334455666666666666555555555444444444443333224444444555555555555555444444443333222..2222233 PP WD40_WDHD1_1st 103 agseDftikvvsvedsskqktleg...hkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktl 166 +++ + + ++++++ ++++eg ++ + ++ ++e++a +s + ++ ++d+ s++ ++++ FUN_000562-T1 1218 SCG---KMSLFDLNKNQMIVQFEGgiwDEGLANGCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQM 1281 222...2233444444444444442222444444444444444444444444444444444444444 PP == domain 4 score: 1.1 bits; conditional E-value: 0.48 WD40_WDHD1_1st 236 ylaaatvdgeilvWdvatkeliervkhek 264 +a + +++++v+d+ + + i+++k e+ FUN_000562-T1 1257 VVAVNSDQKSLCVYDMHSGQRISQMKCEH 1285 45666677777777777777777776654 PP == domain 5 score: -1.3 bits; conditional E-value: 2.6 WD40_WDHD1_1st 142 y 142 + FUN_000562-T1 1440 V 1440 1 PP >> nSTAND1 Novel STAND NTPase 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 0.0 3e-09 1.5e-06 8 126 .. 321 451 .. 319 570 .. 0.67 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 3e-09 nSTAND1 8 FeeedaelFfGRerlveellerlrek..rllavvGaSGsGKSSlvrAGlipalr.elegseewevlev.ltPgedplealaeal......laeaea 93 F +++ + F+GR++ ++++ + l+++ + l+++G+SG+GK+S++ i++ + ++++++++ + + +tP+++ ++ l +++ ++++ FUN_000562-T1 321 FCQNKCSTFYGRNEILDQCRAYLKDDrqNPLVIYGQSGCGKTSVMSM--IAKEAwNISSQSNVVIRYIgTTPNSSQIRLLLRSVceqicsIYGQNP 414 8889999****************9754468**************984..54444434444444444332388888888888765566666344444 PP nSTAND1 94 aaleeepealae....lrealkeeerlllvvDqfEel 126 +++++e ++l+e + + +keee+l+++ D +++ FUN_000562-T1 415 HTIRKEIKELHEdfmsCLQLAKEEEPLFIFFDSLDQF 451 4445555444444322555666666999999887764 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.2 6.5e-08 3.4e-05 108 176 .. 829 897 .. 813 904 .. 0.89 2 ? -1.4 0.0 2.6 1.3e+03 208 310 .. 906 1013 .. 896 1032 .. 0.57 3 ? 0.7 0.0 0.61 3.2e+02 127 183 .. 1094 1149 .. 1086 1153 .. 0.76 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 6.5e-08 Beta-prop_Aladin 108 pghs.pvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssv 176 +gh+ p+t ++ s +G+lL+sa pvd++ vWdv+ + v + g+ v++++ s d+s +++++ ss+ FUN_000562-T1 829 SGHQlPITALSSSADGKLLASA-PVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTSAISSI 897 55544************99986.99***************************************999886 PP == domain 2 score: -1.4 bits; conditional E-value: 2.6 Beta-prop_Aladin 208 vllfateeepviyslsfkeeeseea.....gskaavvvadlskveletede.eikvggevqslawdpkgerlavlleeselvavfktrlsp 292 +f+++++ iy+ + e+e++ k++++++dl+ +l e + + + g sl+ + e vl +++ +a +t+ + FUN_000562-T1 906 QRMFSVSQDHAIYAAPICLLEKEKRilmaaFIKSSIKLYDLQAGSLALEIDdNSESDGISSSLCLC-TMEDQSVLYANTSNLATTTTTWVR 995 557777788888877766665555455655667777777777776665533255566666666654.344445555555555555555555 PP Beta-prop_Aladin 293 vlellPcglvkgeegevp 310 + +l ++ ++ ++ FUN_000562-T1 996 QANLHTYDVLDIVQISSN 1013 555554444444444444 PP == domain 3 score: 0.7 bits; conditional E-value: 0.61 Beta-prop_Aladin 127 saspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvwete 183 sa +++i ++d + ++ + + + l+++ d s++++a+ ++ r+w+ + FUN_000562-T1 1094 SANVFHAEIKIFDLVSGEIIQWMLKYPSSIHLVQY-IDSSHVITASRDKIIRLWDLK 1149 56666777777777777777766666666666665.799***************986 PP >> ATPase_2 ATPase domain predominantly from Archaea # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 3.2e-08 1.7e-05 1 68 [. 329 398 .. 329 465 .. 0.62 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 3.2e-08 ATPase_2 1 FvdRekelkeleelaergtneiiviYGpegcGKtallkeiienleelgk..eviYvsaleeeseskldef 68 F+ R++ l++ + +++ ++++++viYG gcGKt+++ i+++ + + +v+ + + ++s+++ FUN_000562-T1 329 FYGRNEILDQCRAYLKDDRQNPLVIYGQSGCGKTSVMSMIAKEAWNISSqsNVVIRYIGTTPNSSQIRLL 398 8889999*******************************99998733332224444444444455555554 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.03 15 12 40 .. 844 872 .. 831 894 .. 0.74 2 ! 9.7 0.2 0.0023 1.2 11 30 .. 1130 1149 .. 1121 1152 .. 0.79 3 ? 0.1 0.0 2.3 1.2e+03 8 41 .. 1251 1284 .. 1249 1294 .. 0.90 4 ? 6.7 0.0 0.019 10 19 50 .. 1450 1483 .. 1425 1492 .. 0.76 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.03 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkkqvGlFvC 40 +l+ sA D+t +Wd ++ ++v F FUN_000562-T1 844 GKLLASAPVDSTCSVWDVNSGRLVRTFEG 872 468899******************99964 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0023 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdre 30 ++ +i+As D+ ++lWd + FUN_000562-T1 1130 DSSHVITASRDKIIRLWDLK 1149 35789************975 PP == domain 3 score: 0.1 bits; conditional E-value: 2.3 Beta-prop_TEP1_C 8 lkltddliisAseDrtvKlWdretkkqvGlFvCe 41 ++ t++++ s +++ ++d ++ +++ + Ce FUN_000562-T1 1251 IHTTHEVVAVNSDQKSLCVYDMHSGQRISQMKCE 1284 67889999999999*******************7 PP == domain 4 score: 6.7 bits; conditional E-value: 0.019 Beta-prop_TEP1_C 19 seDrtvKlW..dretkkqvGlFvCeapvlvlevn 50 s+Dr++++W d++ + ++ +F+ +a v++++++ FUN_000562-T1 1450 SKDRSIRFWnlDKDRMELLTVFTPDAKVSSMNIS 1483 99*******555778999***********99875 PP >> WD40_like WD40-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.2 1e-05 0.0054 8 189 .. 840 1027 .. 835 1038 .. 0.78 2 ! 10.5 0.2 0.00075 0.39 23 177 .. 1101 1302 .. 1096 1309 .. 0.83 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 1e-05 WD40_like 8 lskkssliayGgkddkctlldlesleevsiiesFsdsviyvkfldndlilvatlDGtilesllenee....viseekiee.disfveviddkil 96 s +++l+a d +c + d++s v +e+ ++ v +v + ++ ++v++ i+ l+n++ v +++ i i +e + ++ FUN_000562-T1 840 SSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTSAISSISAWRLSNGQrmfsVSQDHAIYAaPICLLEKEKRILM 933 57788888888899****************************************************9666444555564414556666666666 PP WD40_like 97 iGtnkGsiylfseDlsieevfvghsseildikieenklysLsetafivfdlesfskkykinlkdikafeivenkeilligkegeil...ilkkn 187 k si l+++ + + ++ +se i++ + e++ + + +s+ + +++ + +i+ i+ ++++ + k n FUN_000562-T1 934 AAFIKSSIKLYDLQAGSLALEIDDNSESDGISS--SLCLCTMEDQSVLYANTSNLATTTTTWVRQANLHTYDVLDIVQISSNQTVHfigVTKMN 1025 667899*****9988888888999999887764..44445556777888888888888888888999999999******999987522245555 PP WD40_like 188 vi 189 ++ FUN_000562-T1 1026 QM 1027 55 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00075 WD40_like 23 kctlldlesleevsiiesFsdsviyvkfldndlilvatlDGtilesllenee......viseekieedis......fveviddki.liGtnkGs 103 +++++dl s e+++ + ++ s+ v+++d +++ a+ D i + +l+++ +++ee+ e +i ++ ++ + ++ + G+ FUN_000562-T1 1101 EIKIFDLVSGEIIQWMLKYPSSIHLVQYIDSSHVITASRDKIIRLWDLKRSAppsaveELKEEQAEVEIVgmyghhAICWEKHALrVVDLQAGH 1194 6789*********************************************998877666777788887875222222466666666356788999 PP WD40_like 104 iylfseDlsieevfvghsseildikie..................................enklysLsetafivfdlesfskkykinlkdika 163 f + ++ ++vfv+ + il + + e ++ ++++ v+d++s + +++ i+ FUN_000562-T1 1195 FIHFVNGVKPQIVFVDDNKAILVSCGKmslfdlnknqmivqfeggiwdeglangcfihtthEVVAVNSDQKSLCVYDMHSGQRISQMKCEHIRR 1288 999***************9999877778899999999999999999999999999999974444444445678899999999999999999999 PP WD40_like 164 feivenkeilligk 177 f ++n +i ++g+ FUN_000562-T1 1289 FVHTPNGDICVLGH 1302 99999999999886 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 1.8e-07 9.2e-05 2 73 .. 352 455 .. 351 461 .. 0.69 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 1.8e-07 AAA 2 llyGppGtGKTllakavakel.....gae..........fveisgselvsk...........................yvgesekklrelfeeakk 55 ++yG G+GKT++++++ake+ + + + ++e +++ +++ ak+ FUN_000562-T1 352 VIYGQSGCGKTSVMSMIAKEAwnissQSNvviryigttpN----------SsqirlllrsvceqicsiygqnphtirkEIKELHEDFMSCLQLAKE 437 78******************76554412232222333330..........1344445555555566667777777777888888888888999999 PP AAA 56 kapsvifiDEiDalakkr 73 ++p if+D +D++++++ FUN_000562-T1 438 EEPLFIFFDSLDQFGPED 455 99************9988 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.033 17 302 340 .. 822 860 .. 818 861 .. 0.93 2 ! 6.5 0.1 0.0095 4.9 282 341 .] 844 902 .. 832 902 .. 0.74 3 ? 0.7 0.1 0.53 2.8e+02 177 233 .. 892 948 .. 861 956 .. 0.79 4 ? -2.8 0.0 6.5 3.4e+03 20 67 .. 965 1015 .. 949 1026 .. 0.60 5 ! 8.1 0.1 0.003 1.6 280 341 .] 1088 1148 .. 1056 1149 .. 0.79 6 ! 10.3 0.1 0.00064 0.33 229 309 .. 1205 1282 .. 1150 1287 .. 0.76 7 ? 1.6 0.0 0.29 1.5e+02 27 42 .. 1450 1465 .. 1328 1492 .. 0.73 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.033 WD40_MABP1-WDR62_2nd 302 GecvatvfGhseivtglkFtedcrhlisvsgDsCifvWr 340 G ++ ++ Gh +t+l ++d++ l s+ Ds vW FUN_000562-T1 822 GPLIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWD 860 677899********************************6 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0095 WD40_MABP1-WDR62_2nd 282 glyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhlisvsgDsCifvWrl 341 g+ +a++ d + s++d +sG +v t G e v + + d l+ +s+ s i Wrl FUN_000562-T1 844 GKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDN-SLVVTSAISSISAWRL 902 5667777778888888888888888888888888888888875.4666677777878876 PP == domain 3 score: 0.7 bits; conditional E-value: 0.53 WD40_MABP1-WDR62_2nd 177 ssitavkfaeeeeklkliscgaDksilfrkaqktkegvefsrehhvvekttlydmev 233 s+i+++ + ++ ++ s + D++i+ + +++ + + + + ++lyd++ FUN_000562-T1 892 SAISSISAWRLSNGQRMFSVSQDHAIYAAPICLLEKEKRILMAAFIKSSIKLYDLQA 948 566666666666677999999999999999999999999999999999999999875 PP == domain 4 score: -2.8 bits; conditional E-value: 6.5 WD40_MABP1-WDR62_2nd 20 agsFltcs.sDdtiRlWnleeks..seetalkrniysnellkvlyvdeels 67 ++s c+ +D+++ n+++ + +++ + + n+++ ++l ++ ++++++ FUN_000562-T1 965 SSSLCLCTmEDQSVLYANTSNLAttTTTWVRQANLHTYDVLDIVQISSNQT 1015 444444441455555555554330033345677899999999999887765 PP == domain 5 score: 8.1 bits; conditional E-value: 0.003 WD40_MABP1-WDR62_2nd 280 psglyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhlisvsgDsCifvWrl 341 +s +++ +++i+d+ sGe++ ++ + + +++ d h+i++s D i +W l FUN_000562-T1 1088 NSRFSASANVFHAEIKIFDLVSGEIIQWMLKYPSSIHLVQYI-DSSHVITASRDKIIRLWDL 1148 555555555567789*****************9999999986.889**************76 PP == domain 6 score: 10.3 bits; conditional E-value: 0.00064 WD40_MABP1-WDR62_2nd 229 ydmevdaskklvavacqDrnirvynvssgkqkksfkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGecvatvf 309 + vd +k ++v+c ++ ++++++ ++ +f g ++g + + va+ + +k+l+++d++sG+ ++++ FUN_000562-T1 1205 QIVFVDD-NKAILVSCG--KMSLFDLNKNQMIVQFEGGIWDEGLANGCFIHTTHEVVAVNSDQKSLCVYDMHSGQRISQMK 1282 4455554.477888886..6889****************************************************999985 PP == domain 7 score: 1.6 bits; conditional E-value: 0.29 WD40_MABP1-WDR62_2nd 27 ssDdtiRlWnleekss 42 s D +iR+Wnl+++ + FUN_000562-T1 1450 SKDRSIRFWNLDKDRM 1465 5566666666665443 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.2 2.4e-06 0.0012 125 198 .. 827 902 .. 823 932 .. 0.83 2 ? 0.5 0.1 0.61 3.2e+02 79 172 .. 1129 1161 .. 1079 1294 .. 0.72 3 ? -0.9 0.0 1.6 8.4e+02 154 230 .. 1366 1442 .. 1361 1465 .. 0.66 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 2.4e-06 Beta-prop_CAF1B_HIR1 125 vlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvat..lssDrslri 198 + Gh + ls s+d+k l s+ vD t +Wdv+ g+ + ++ + v va+ n++v+t +ss + r+ FUN_000562-T1 827 SMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVTsaISSISAWRL 902 689***************************************************9999999998822344444444 PP == domain 2 score: 0.5 bits; conditional E-value: 0.61 Beta-prop_CAF1B_HIR1 79 spsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlswspdskklisgsvDntailWdvekgkkl 165 s+++i++s D + lWd++++ FUN_000562-T1 1129 ID-------------------------------------------------------------SSHVITASRDKIIRLWDLKRSAPP 1154 44.............................................................444444444444444444444333 PP Beta-prop_CAF1B_HIR1 166 ailkdhk 172 + +++ k FUN_000562-T1 1155 SAVEELK 1161 3332222 PP == domain 3 score: -0.9 bits; conditional E-value: 1.6 Beta-prop_CAF1B_HIR1 154 ailWdvekgkklailkdhkgf.vqgvawdPknqyvatlssDrslrifdiktkkvvarvskaklp.vkeekelkekevrl 230 a+++dve gk l ++ ++ v + P+ + + D ++++ di t k+++r+++a+l v++ +++++ +v + FUN_000562-T1 1366 AVVFDVETGKLL--FESATNYqVHTSVILPETRHLLLGLFDGAIQLDDIDTGKCLHRINRAHLGsVHRISTTDDGTVAM 1442 677777777653..34333332556666777777777788889999999999999999999887344444444445554 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 0.00068 0.36 32 99 .. 826 891 .. 819 904 .. 0.87 2 ! 7.4 0.0 0.0064 3.4 88 146 .. 1032 1089 .. 990 1093 .. 0.78 3 ? -2.8 0.0 7.9 4.1e+03 144 159 .. 1451 1466 .. 1428 1480 .. 0.70 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00068 WD40_MABP1-WDR62_1st 32 hilntsrkalsalafspdGkylvtGesghlpavrvwdvaeksqvaelqkhkygvacvafspnekyivs 99 h ++ + ++al+ s+dGk+l + + vwdv+ + v ++++ v va+s +++ +v+ FUN_000562-T1 826 HSMSGHQLPITALSSSADGKLLASAPVD--STCSVWDVNSGRLVRTFEGIGEDVCHVAISLDNSLVVT 891 667778889*************987665..67899*************99999999999999888875 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0064 WD40_MABP1-WDR62_1st 88 vafspnekyivsvgyqhdmvvnvwdwkkdvvvaa.nkvsskvtavsfsedssyfvtvGnr 146 spn+k sv q ++++wd k+++vv sskv + ++s d+s +t Gn FUN_000562-T1 1032 TEGSPNTKKESSV--QTFFTLELWDLKRKIVVHQlVEPSSKVRCFTLSMDKSKALTLGNS 1089 4558888888888..788899******99999762578********************95 PP == domain 3 score: -2.8 bits; conditional E-value: 7.9 WD40_MABP1-WDR62_1st 144 Gnrhvkfwyldaskek 159 +r ++fw ld+ + + FUN_000562-T1 1451 KDRSIRFWNLDKDRME 1466 3799999999987655 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 2e-06 0.001 4 72 .. 347 425 .. 344 474 .. 0.69 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 2e-06 AAA_22 4 tagilvltGesGtGKTtllrrlleqldee....ddsvv...lvelpsst....spkdllrellralglelek.elskeell 72 +++ lv++G+sG+GKT ++ ++++++ + +++vv + p+s+ ++++++++++ +g+ +++ +++ +el FUN_000562-T1 347 RQNPLVIYGQSGCGKTSVMSMIAKEA--WnissQSNVViryIGTTPNSSqirlLLRSVCEQICSIYGQNPHTiRKEIKELH 425 7889********************98..55698555556755566666635444555566666666655555555544444 PP >> DUF4062 Domain of unknown function (DUF4062) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.0 4.3e-06 0.0022 30 78 .. 34 89 .. 1 91 [. 0.75 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 4.3e-06 DUF4062 30 vlmeefaasdesqlelclkeidecd......vyvlilggrYGsi.deeglSytelE 78 ++ +++a+d+s+lelclkei+ c+ ++ ++g++YG + ++++ te E FUN_000562-T1 34 WGVRDESADDHSTLELCLKEIRACQelstgpNFMALVGQKYGFRpLPSKIATTEFE 89 3444599*******************999999**********99888888888766 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.1 0.00042 0.22 114 223 .. 822 866 .. 801 917 .. 0.72 2 ? 6.0 0.4 0.012 6.3 80 166 .. 1076 1160 .. 987 1191 .. 0.67 3 ? 2.7 0.0 0.12 64 83 158 .. 1385 1465 .. 1351 1490 .. 0.76 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00042 NBCH_WD40 114 GrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlrarssekrvrntqtelsrkdvviaekplhilcGhddiitclfvsveldivisGsk 209 G l+ s++ h+ +++++ ++dg++la+ d+t vw+v +r FUN_000562-T1 822 GPLIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNSGR---------------------------------------------------- 865 56666666666666666666677777776677777777666554.................................................... PP NBCH_WD40 210 dgtcifhtlreGry 223 FUN_000562-T1 866 -------------L 866 .............3 PP == domain 2 score: 6.0 bits; conditional E-value: 0.012 NBCH_WD40 80 lgaqcfatlqtksenfliscGnwensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlrarssekrvrnt 166 l+ +l + f s ++ ++ l G+++q + ++ + v+ d s ++t s+d + +w++ r+ v + FUN_000562-T1 1076 LSMDKSKALTLGNSRFSASANVFHAEIKIFDLVSGEIIQWMLKYPSSIHLVQY-IDSSHVITASRDKIIRLWDLKRSAPPSA-VEEL 1160 3333334555566778888888899999*************999988887764.69999***************98765443.2333 PP == domain 3 score: 2.7 bits; conditional E-value: 0.12 NBCH_WD40 83 qcfatlqtksenfliscGnwensfqvislsdGrlvqsi.rqhkdvvscvavtsdgsvlat..G...sydttvmvwevlrars 158 q+ +++ + +l G ++ + q+ ++ G+ + i r h v ++ t dg+v t G s+d ++ w++ + r+ FUN_000562-T1 1385 QVHTSVILPETRHL-LLGLFDGAIQLDDIDTGKCLHRInRAHLGSVHRISTTDDGTVAMTtaGgldSKDRSIRFWNLDKDRM 1465 44444444444444.46999*************99887478**************997763323557888999998877665 PP >> Torsin Torsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 5e-06 0.0026 35 103 .. 333 396 .. 323 412 .. 0.85 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 5e-06 Torsin 35 klvvksvkaflenekpkkpLvlsfhGwtGtGknyvaeiiaenlyrdGlrsdyvkkfvatadfPkkkkve 103 + ++ +a+l++++ + pLv+ +G++G Gk v ++ia++ ++ ++s++v +++t+ P+++++ FUN_000562-T1 333 NEILDQCRAYLKDDR-QNPLVI--YGQSGCGKTSVMSMIAKEAWNISSQSNVVIRYIGTT--PNSSQIR 396 678888999998765.679986..8********************************996..6766665 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.8 0.00059 0.31 65 145 .. 831 909 .. 824 1027 .. 0.90 2 ? 0.2 0.1 0.76 4e+02 88 172 .. 1220 1307 .. 1205 1320 .. 0.65 3 ? 6.2 0.1 0.011 5.9 77 128 .. 1394 1443 .. 1368 1448 .. 0.88 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00059 Beta-prop_VPS8 65 eqgaVsalafnadstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikFtddptlalvs.DsgGsvFelsfkrklg 145 +q +++al+ +ad+ l+ + + +wD+++g+l+rt + g+ v+h+ d++l+++s s+ s++ ls +++ FUN_000562-T1 831 HQLPITALSSSADGKLLASAPVDSTCSVWDVNSGRLVRTFEG---IGEDVCHVAISLDNSLVVTSaISSISAWRLSNGQRMF 909 6889**********************************9875...68899******99999999977999999998776664 PP == domain 2 score: 0.2 bits; conditional E-value: 0.76 Beta-prop_VPS8 88 GqilmwDlsngkllrtisdahppgtavlhikFtddpt..lalvsDsgG.svFelsfkrklgvrsv.eskclfsgsrgeVcaleplllee 172 G++ ++Dl++ +++ + + ++ + F+++ + +a+ sD++ +v++++ +++ ++ + ++++ +g++c+l ++++ FUN_000562-T1 1220 GKMSLFDLNKNQMIVQFEGGIWD-EGLANGCFIHTTHevVAVNSDQKSlCVYDMHSGQRISQMKCeHIRRFVHTPNGDICVLGHSMIND 1307 55666666666666665544433.34445555555443267777765438999988777655555157888999999999998877765 PP == domain 3 score: 6.2 bits; conditional E-value: 0.011 Beta-prop_VPS8 77 dstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikFtddptlalv 128 + +ll G +G i + D+ +gk+l++i+ ah v i+ tdd t+a++ FUN_000562-T1 1394 ETRHLLLGLFDGAIQLDDIDTGKCLHRINRAHLGS--VHRISTTDDGTVAMT 1443 55689***************************876..888999999998876 PP >> Bac_DnaA Bacterial DnaA ATPAse domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 7e-06 0.0037 31 70 .. 345 386 .. 337 406 .. 0.80 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 7e-06 Bac_DnaA 31 gkkynPlfiygevGlGkthLlkaignevlenap..elrvvYl 70 + + nPl+iyg++G Gkt ++ i++e+ + ++ ++ + Y+ FUN_000562-T1 345 DDRQNPLVIYGQSGCGKTSVMSMIAKEAWNISSqsNVVIRYI 386 5678*********************99976554005555676 PP >> nSTAND6 Novel STAND NTPase 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 8.6e-06 0.0045 2 52 .. 330 383 .. 329 428 .. 0.77 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 8.6e-06 nSTAND6 2 yGRekllkklvakLke..kpillvyGlrGnGKstlieelgkka.alkgkeavri 52 yGR+++l++ a Lk+ ++ l++yG +G GK++++ ++k+a ++++++ v i FUN_000562-T1 330 YGRNEILDQCRAYLKDdrQNPLVIYGQSGCGKTSVMSMIAKEAwNISSQSNVVI 383 **********99998633788****************99977614444555544 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 2.8 1.4e+03 84 105 .. 142 163 .. 135 165 .. 0.83 2 ! 14.7 0.0 4.9e-05 0.025 6 44 .. 335 375 .. 330 450 .. 0.82 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 2.8 nSTAND3 84 sknedskllsfikrirksknkk 105 + ++++k++ ++++i+++++k+ FUN_000562-T1 142 ASKQWNKIFAQLQKIVRRGAKR 163 6789*************99986 PP == domain 2 score: 14.7 bits; conditional E-value: 4.9e-05 nSTAND3 6 afekaleiL..eknkvviitGepGiGKttlaemLalkllde 44 +++++ L ++++ ++i G++G GKt+++ m+a ++++ FUN_000562-T1 335 ILDQCRAYLkdDRQNPLVIYGQSGCGKTSVMSMIAKEAWNI 375 5566666662245689*********************9983 PP >> HRI2_3H Heme-regulated eIF-2-alpha kinase, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.5 4.4e-05 0.023 2 28 .. 393 419 .. 392 434 .. 0.85 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 4.4e-05 HRI2_3H 2 vpsslLlvSLlehlCslyekdpeksrk 28 ++ +lLl S +e++Cs+y ++p+ rk FUN_000562-T1 393 SQIRLLLRSVCEQICSIYGQNPHTIRK 419 6889******************98776 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 7.3e-05 0.038 13 79 .. 344 411 .. 332 444 .. 0.72 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 7.3e-05 NB-ARC 13 lekdelq.ivalvGmgGvGKttLakeifnklsevegrFdvva.wvvvsktf.seeelledilkeLgkeed 79 d++q + ++G G+GKt +++ i ++ +++++ +vv+ ++ + ++ +++ ll++++++++ FUN_000562-T1 344 K--DDRQnPLVIYGQSGCGKTSVMSMIAKEAWNISSQSNVVIrYIGTTPNSsQIRLLLRSVCEQICSIYG 411 3..55555899*******************9999999996661455544443677788888888876544 PP >> ABC_tran ABC transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 9.1e-05 0.047 14 40 .. 351 377 .. 343 438 .. 0.81 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 9.1e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF ABC_tran 14 lalvGenGaGKStLlkllagllkpteG 40 l++ G++G+GK+++++++a++ + + FUN_000562-T1 351 LVIYGQSGCGKTSVMSMIAKEAWNISS 377 799*****************9987444 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.38 2e+02 93 137 .. 823 866 .. 813 883 .. 0.84 2 ? 0.4 0.1 0.56 2.9e+02 285 344 .. 927 985 .. 919 1002 .. 0.85 3 ? 7.2 0.0 0.0049 2.5 282 306 .. 1126 1150 .. 1113 1155 .. 0.89 4 ? -1.9 0.0 2.8 1.5e+03 294 308 .. 1450 1464 .. 1424 1471 .. 0.72 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.38 Beta-prop_IFT140_1st 93 eltelpklhkaeitvlewssngsrLvsgdksGvlvvWkldqrGrl 137 l++ + h+ it l+ s+ g+ L+s+ + vW +++ Grl FUN_000562-T1 823 PLIHSMSGHQLPITALSSSADGKLLASAPVDSTCSVWDVNS-GRL 866 566677889****************************9975.665 PP == domain 2 score: 0.4 bits; conditional E-value: 0.56 Beta-prop_IFT140_1st 285 aekglLitatgesvirlwdlerddnyvLsldeklgfekgEaincvsyckakgiLaaGtnk 344 ek +L+ a s i+l+dl+ + +L++d++++ + + c+ + + +L a t++ FUN_000562-T1 927 KEKRILMAAFIKSSIKLYDLQAG-SLALEIDDNSESDGISSSLCLCTMEDQSVLYANTSN 985 57899***************987.689999999999999999999999999999998875 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0049 Beta-prop_IFT140_1st 282 iiwaekglLitatgesvirlwdler 306 + +++++ +ita+ +++irlwdl+r FUN_000562-T1 1126 VQYIDSSHVITASRDKIIRLWDLKR 1150 56789999***************97 PP == domain 4 score: -1.9 bits; conditional E-value: 2.8 Beta-prop_IFT140_1st 294 tgesvirlwdlerdd 308 + ++ ir+w+l++d FUN_000562-T1 1450 SKDRSIRFWNLDKDR 1464 45789*******986 PP >> RNA_helicase RNA helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 0.00015 0.081 2 27 .. 352 388 .. 351 441 .. 0.64 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.00015 RNA_helicase 2 wlyGpsgeGKStlakelakallkkl...........k 27 ++yG+sg+GK+++++ +ak+ + + FUN_000562-T1 352 VIYGQSGCGKTSVMSMIAKEAWNISsqsnvviryigT 388 89****************9987444344455555551 PP >> B-prop_COPA_B_2nd COPA/B second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.93 4.9e+02 111 176 .. 837 905 .. 829 960 .. 0.65 2 ? -0.3 0.0 1.7 8.7e+02 120 184 .. 1177 1247 .. 1155 1262 .. 0.70 3 ? 7.7 0.0 0.0062 3.2 125 164 .. 1263 1311 .. 1246 1356 .. 0.73 4 ? -1.5 0.0 3.8 2e+03 118 163 .. 1396 1444 .. 1379 1479 .. 0.74 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.93 B-prop_COPA_B_2nd 111 kifgggtGslLgvksess.vilYDwqqkklvreid..vkavkyVvWsddgelvallskdtvyilnknle 176 + +++ G lL + +s +++D+++++lvr + ++v +V s d++lv + +++ + + FUN_000562-T1 837 ALSSSADGKLLASAPVDStCSVWDVNSGRLVRTFEgiGEDVCHVAISLDNSLVVTSAISSISAWRLSNG 905 566667788888887554156899999999999996334589999999999988776666555444443 PP == domain 2 score: -0.3 bits; conditional E-value: 1.7 B-prop_COPA_B_2nd 120 lLgvksessvilYDwqqkklvreid.vkavkyVvWsddgelvallskdtvyilnknleav.......eegved 184 ++ +++ + + D+q + +++ ++ vk+ + V+ +d+ ++ ++k +++ lnkn+ v +eg+ + FUN_000562-T1 1177 AICWEKHA-LRVVDLQAGHFIHFVNgVKP-QIVFVDDNKAILVSCGKMSLFDLNKNQMIVqfeggiwDEGLAN 1247 44555555.88889999999999998888.8888888888888999999999999998667777776666654 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0062 B-prop_COPA_B_2nd 125 sessvilYDwqqkklvreidvkavkyVvWsddgelvall.........s 164 +++s+++YD+ +++ +++++ + +++ v +g+++ l + FUN_000562-T1 1263 DQKSLCVYDMHSGQRISQMKCEHIRRFVHTPNGDICVLGhsmindeepA 1311 5677******************************999875555555543 PP == domain 4 score: -1.5 bits; conditional E-value: 3.8 B-prop_COPA_B_2nd 118 GslLgvksessvilYDwqqkklvreidvk...avkyVvWsddgelvall 163 +lL+ ++ + l D++++k +++i+ +v+++ ddg++++ + FUN_000562-T1 1396 RHLLLGLFDGAIQLDDIDTGKCLHRINRAhlgSVHRISTTDDGTVAMTT 1444 456666666669999*******999985523369999999999877765 PP >> Zeta_toxin Zeta toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.0004 0.21 4 47 .. 335 382 .. 332 385 .. 0.77 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.0004 Zeta_toxin 4 llkdkk.ypsqerPvavllaGqpGAGKtelaellkeelq...rqgnvv 47 +l++ + y ++ r +++ Gq+G GKt++++++++e +q+nvv FUN_000562-T1 335 ILDQCRaYLKDDRQNPLVIYGQSGCGKTSVMSMIAKEAWnisSQSNVV 382 55555557777777778899***************9976676777777 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00026 0.13 23 114 .. 336 431 .. 328 438 .. 0.76 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00026 TniB 23 LealleapkkkrmpnlllvGdsnnGKstivekFarlhpaqkeedeeevpvvvvqappepdekrlyaaiLeaLea.....pikardrlskleqqvle 113 L++ + k +r + l+++G+s +GK+ +++ a++ + +++++ +++ + +p++++ + l +++ e+++ p+ +r+++++l+++ ++ FUN_000562-T1 336 LDQCRAYLKDDRQNPLVIYGQSGCGKTSVMSMIAKEAWNISSQSNVVIRYIG-TTPNSSQIRLLLRSVCEQICSiygqnPHTIRKEIKELHEDFMS 430 556667788899999*******************999999988888888765.5899999999999999999751111155555566666655555 PP TniB 114 l 114 FUN_000562-T1 431 C 431 5 PP >> Rad17 Rad17 P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00068 0.35 40 69 .. 343 372 .. 334 408 .. 0.80 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00068 Rad17 40 LesrkkriLLisGPsGCgkstvvkvLskel 69 L+ +++ L+i G sGCgk+ v+ +++ke FUN_000562-T1 343 LKDDRQNPLVIYGQSGCGKTSVMSMIAKEA 372 555666789*******************95 PP >> ATP-synt_ab ATP synthase alpha/beta family, nucleotide-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00065 0.34 17 52 .. 351 389 .. 348 405 .. 0.80 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00065 xxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxx RF ATP-synt_ab 17 lgifggsgvGktvlaatiakqasa...dvvvvyvliGer 52 l+i g+sg+Gkt+++++iak+a + + vv+ iG FUN_000562-T1 351 LVIYGQSGCGKTSVMSMIAKEAWNissQSNVVIRYIGTT 389 579*****************9844577667777788765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1545 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1008 (0.0394598); expected 510.9 (0.02) Passed bias filter: 814 (0.0318653); expected 510.9 (0.02) Passed Vit filter: 139 (0.00544138); expected 25.5 (0.001) Passed Fwd filter: 49 (0.00191818); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 49 [number of targets reported over threshold] # CPU time: 0.73u 0.41s 00:00:01.13 Elapsed: 00:00:00.50 # Mc/sec: 12516.92 // Query: FUN_000563-T1 [L=323] Description: FUN_000563 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.15 13.4 0.5 0.31 12.4 0.4 1.6 1 CAP Cysteine-rich secretory protein family 1.4 9.6 7.3 1.5 9.4 1.0 2.6 2 DUF771 Domain of unknown function (DUF771) 1.5 9.2 3.3 2.1 8.7 0.1 2.1 2 PhageMin_Tail Phage-related minor tail protein 2.4 7.3 16.3 3.1 6.9 16.3 1.2 1 FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalyti 5.5 7.8 30.2 5.2 7.9 10.4 2.3 2 DUF4200 Domain of unknown function (DUF4200) 9 7.2 20.7 0.23 12.3 2.6 3.9 4 Csm1_N Csm1 N-terminal domain Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.4 7.3e-05 0.31 7 57 .. 182 231 .. 179 280 .. 0.76 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7.3e-05 CAP 7 lRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaag 57 +R+++ +++L++d+ ++++A ++a+++ + + +++++ i +r+ ++g FUN_000563-T1 182 YRQNKEMKKLEYDNVASRQALKNARDLITD-LKAKIEKRNKYIKQRNLKEG 231 9*************************9553.55555555555555555555 PP >> DUF771 Domain of unknown function (DUF771) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 1.0 0.00035 1.5 7 56 .. 189 239 .. 187 260 .. 0.79 2 ? 2.3 1.9 0.061 2.6e+02 21 77 .. 264 322 .. 246 323 .] 0.71 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00035 DUF771 7 dkeeyeeLk.kkdlegvyWnmkdlekklskksewikenlllnpkfkkeldv 56 +k ey+++ ++ l+ + dl+ k++k+++ ik++ l++ ++++ +++ FUN_000563-T1 189 KKLEYDNVAsRQALKNARDLITDLKAKIEKRNKYIKQRNLKEGDLARDVEA 239 5778888884555666667799************************99987 PP == domain 2 score: 2.3 bits; conditional E-value: 0.061 DUF771 21 gvyWnmkdlekklskksewikenlllnpkfkkeldvenggfvlypk..ekGskwsfkak 77 + mk++e + ++ +++ +++l +n+++ ++++++++ ++ ++ ek kw+ +a+ FUN_000563-T1 264 AKDDAMKEIEDERKRMESVYQDDLRENTELMRKIETREKQITQLREktEKAVKWKTNAR 322 44456888888888888888999999**********99888888775567778887776 PP >> PhageMin_Tail Phage-related minor tail protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.1 0.00048 2.1 125 191 .. 160 224 .. 157 230 .. 0.80 2 ? 0.7 0.6 0.14 5.9e+02 141 167 .. 254 280 .. 241 316 .. 0.51 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00048 PhageMin_Tail 125 aa.agisgseAgtalknflarlaaptkeaaealkklGisakdangkmkslkeiledlkkklkkltda.q 191 a+ +++ ++g ++++ l+ + +++ +kkl + + + +k++ +++ dlk k++k ++ + FUN_000563-T1 160 ASpETTKDTVVGKSFRENLSLI----YRQNKEMKKLEYDNVASRQALKNARDLITDLKAKIEKRNKYiK 224 55566788899*********99....899******996644555777***************9988733 PP == domain 2 score: 0.7 bits; conditional E-value: 0.14 PhageMin_Tail 141 flarlaaptkeaaealkklGisakdan 167 ++++++ + ++ +a+k++ + k ++ FUN_000563-T1 254 IMKNMNHALAAKDDAMKEIEDERKRME 280 333333333555666666532232222 PP >> FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalytic domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 16.3 0.00072 3.1 45 187 .. 171 313 .. 124 322 .. 0.69 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.00072 FUT8_N_cat 45 leevlekleelkkqneelkellekrleeseeekkkaeeklksleeklekakekleeakkskknelsleyEvlrrrleneikElwyllsselkklkk 140 ++ e+l+ + +qn+e+k+l +++ ++++ k+ a++ +++l++k+ek+++ + ++++ k+ l+ + E lrr+ +++++E ++++ + l++ FUN_000563-T1 171 GKSFRENLSLIYRQNKEMKKLEYDNVASRQALKN-ARDLITDLKAKIEKRNKYI-KQRNLKEGDLARDVEALRRERDEKLQEYKSIMKNMNHALAA 264 4667788999999*******98887777666666.66699*********98777.5555889999************************9999998 PP FUT8_N_cat 141 eekee.elekeieel...lellaeqkrslladieklekadgaeewrkkeak 187 ++++ e+e+e +++ + ++++l+ +ie+ ek +++++r+k+ k FUN_000563-T1 265 KDDAMkEIEDERKRMesvYQDDLRENTELMRKIETREK--QITQLREKTEK 313 88877433333333300033333333444444443222..23344444333 PP >> DUF4200 Domain of unknown function (DUF4200) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 13.7 0.013 57 15 90 .. 181 259 .. 175 265 .. 0.85 2 ? 7.9 10.4 0.0012 5.2 43 98 .. 258 313 .. 255 319 .. 0.91 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.013 DUF4200 15 ldakkeeierleellkereeelekke...qelkedlvkfdkflkeneakreraekkaeeetkekkekekeikklkaele 90 + ++++e+++le ++ + +++l++++ +lk++++k +k++k+ + k+ + + +e ++e++ek +e k + ++++ FUN_000563-T1 181 IYRQNKEMKKLEYDNVASRQALKNARdliTDLKAKIEKRNKYIKQRNLKEGDLARDVEALRRERDEKLQEYKSIMKNMN 259 6789999999999999999999998855567888999999999999999999999999999999999999998887775 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0012 DUF4200 43 lkedlvkfdkflkeneakreraekkaeeetkekkekekeikklkaeleelkseisk 98 ++ l+ d+ +ke e++r+r e ++++ +e++e++++i+ ++++++l+++ +k FUN_000563-T1 258 MNHALAAKDDAMKEIEDERKRMESVYQDDLRENTELMRKIETREKQITQLREKTEK 313 56667888999****************************************99987 PP >> Csm1_N Csm1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.8 7.5e+03 6 15 .. 38 47 .. 37 48 .. 0.84 2 ? 5.3 1.1 0.0082 35 23 63 .. 189 229 .. 187 236 .. 0.87 3 ? 0.6 0.5 0.24 1e+03 34 64 .. 246 276 .. 238 281 .. 0.56 4 ? 12.3 2.6 5.4e-05 0.23 27 53 .. 288 314 .. 284 322 .. 0.89 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.8 Csm1_N 6 eYKesVqerl 15 +YK+ V++++ FUN_000563-T1 38 NYKACVEQKI 47 7*****9986 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0082 Csm1_N 23 sklvhENsvLsqkletkdqeiesLkeqlaeleekvkeleer 63 +kl + N+ +q+l++ + i Lk+++++ ++ +k+ + + FUN_000563-T1 189 KKLEYDNVASRQALKNARDLITDLKAKIEKRNKYIKQRNLK 229 57778999**********************99999887655 PP == domain 3 score: 0.6 bits; conditional E-value: 0.24 Csm1_N 34 qkletkdqeiesLkeqlaeleekvkeleerr 64 +kl+ ++ ++++ + la+ + +ke+e++r FUN_000563-T1 246 EKLQEYKSIMKNMNHALAAKDDAMKEIEDER 276 4455555555555555566666666666555 PP == domain 4 score: 12.3 bits; conditional E-value: 5.4e-05 Csm1_N 27 hENsvLsqkletkdqeiesLkeqlael 53 EN+ L++k+et++++i +L+e+ +++ FUN_000563-T1 288 RENTELMRKIETREKQITQLREKTEKA 314 7*********************98875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (323 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3061 (0.119828); expected 510.9 (0.02) Passed bias filter: 721 (0.0282247); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.35u 0.41s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3134.59 // Query: FUN_000564-T1 [L=160] Description: FUN_000564 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0085 16.8 3.0 0.023 15.5 1.0 2.6 2 ExsD_M Antiactivator protein ExsD helical hairpin doma ------ inclusion threshold ------ 0.028 14.3 25.0 0.13 12.1 16.0 2.3 2 GAS Growth-arrest specific micro-tubule binding 0.044 14.3 4.2 0.044 14.3 4.2 2.7 3 TMF_DNA_bd TATA element modulatory factor 1 DNA binding 0.044 14.7 0.3 0.044 14.7 0.3 2.0 2 Aida_N Aida N-terminus 0.14 13.2 17.6 0.26 12.3 8.9 2.8 3 RUNDC1 RUN domain-containing protein 1 domain 0.17 12.2 18.1 0.31 11.3 18.1 1.4 1 CT398_CC CT398-like coiled coil hairpin domain 0.2 11.6 16.2 0.39 10.6 16.1 1.6 1 Exonuc_VII_L Exonuclease VII, large subunit 0.42 11.5 19.8 1.5 9.8 3.1 3.5 3 Med28 Mediator complex subunit 28 0.53 11.1 15.4 0.48 11.2 2.9 2.2 2 TSNAXIP1_N Translin-associated factor X-interacting N-term 0.68 10.1 21.6 0.63 10.2 14.4 2.1 2 SHE3 SWI5-dependent HO expression protein 3 0.71 10.4 13.3 0.17 12.4 5.7 2.4 2 DUF1664 Protein of unknown function (DUF1664) 1 8.3 28.6 1.3 8.0 15.5 2.0 2 TPH Trichohyalin-plectin-homology domain 1.3 10.0 11.4 2.5 9.1 1.7 2.5 2 DUF4094 Domain of unknown function (DUF4094) 1.8 9.4 17.5 4.3 8.2 5.3 2.8 3 DUF641 Plant protein of unknown function (DUF641) 3.1 8.0 12.3 2.2 8.5 7.6 2.0 2 DUF745 Protein of unknown function (DUF745) 4.3 8.0 19.0 5.4 7.7 18.2 1.5 1 KIF9 Kinesin-like protein KIF9 domain 6.1 7.5 21.1 21 5.8 5.5 2.4 2 TMF_TATA_bd TATA element modulatory factor 1 TATA binding 7.7 5.6 13.9 8.6 5.5 13.9 1.0 1 FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalytic 9 7.0 10.2 5.9 7.6 2.2 2.6 2 DUF948 Bacterial protein of unknown function (DUF948) Domain annotation for each model (and alignments): >> ExsD_M Antiactivator protein ExsD helical hairpin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.2 1.7e+03 43 55 .. 39 51 .. 23 58 .. 0.56 2 ! 15.5 1.0 1.7e-05 0.023 28 64 .. 95 130 .. 72 132 .. 0.92 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.2 ExsD_M 43 keVaklqaalqer 55 +e+ +l+++l + FUN_000564-T1 39 HEIDELKTRLARK 51 2344444444444 PP == domain 2 score: 15.5 bits; conditional E-value: 1.7e-05 ExsD_M 28 rvAElvseqaREelakeVaklqaalqerkalLekkLl 64 rv E q REe k +klq +++r L+++L+ FUN_000564-T1 95 RVKENAIGQVREEIDK-YSKLQKEVKQRNDVLKGRLE 130 67788899********.*******************8 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 16.0 9.7e-05 0.13 58 146 .. 8 100 .. 2 104 .. 0.79 2 ? 8.1 1.6 0.0016 2.2 35 77 .. 101 143 .. 98 148 .. 0.89 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 9.7e-05 GAS 58 rlkepLekaeeeveeLkkq....leeyekdkqslknlkarlkelekelkelkwehevleqrfekverErdelyekfeeaiqdvqqktglknll 146 + + ++++ ++e+ L+k+ ++e ++ +++ ++lk+rl + ++ lk+ + ++ l+ + ek+ E+++l ++++++i+++q++ +k++ FUN_000564-T1 8 QQERTIQENRQELLLLEKNkvdiMNEVARANHEIDELKTRLARKDNLLKHSQDLQDTLLLQAEKLRFEKEQLNQRCDNVINEMQERLRVKENA 100 455667777888888887611124566778889999999999999999999999999999999999999999999999999999999999875 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0016 GAS 35 iaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkql 77 i +++++ +++k+ +e++q+n lk Lek e+ v Lk +l FUN_000564-T1 101 IGQVREEIDKYSKLQKEVKQRNDVLKGRLEKREKIVTGLKTKL 143 66788999999*************************9999988 PP >> TMF_DNA_bd TATA element modulatory factor 1 DNA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 5.1 0.0054 7.3 30 73 .. 8 51 .. 2 52 .. 0.92 2 ? -0.9 0.1 1.8 2.4e+03 21 34 .. 58 71 .. 52 85 .. 0.49 3 ? 14.3 4.2 3.3e-05 0.044 1 57 [. 88 144 .. 88 151 .. 0.93 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0054 TMF_DNA_bd 30 klnntikkLrkknkeleksvkelkkkleklekeleeleerlkea 73 +++ ti + r+++ lek+ + ++ ++ + e++el+ rl+++ FUN_000564-T1 8 QQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARK 51 68899************************************998 PP == domain 2 score: -0.9 bits; conditional E-value: 1.8 TMF_DNA_bd 21 GekLskkelklnnt 34 ++L+++ l + ++ FUN_000564-T1 58 SQDLQDTLLLQAEK 71 44444444444333 PP == domain 3 score: 14.3 bits; conditional E-value: 3.3e-05 TMF_DNA_bd 1 sslekklkeKDeqIaqLmeEGekLskkelklnntikkLrkknkeleksvkelkkkle 57 +++++ l+ K++ I q +eE k+sk + + ++ + L+ +++ ek v+ lk kl FUN_000564-T1 88 NEMQERLRVKENAIGQVREEIDKYSKLQKEVKQRNDVLKGRLEKREKIVTGLKTKLT 144 5899***********************9999999999***************99986 PP >> Aida_N Aida N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.2 1.1 1.5e+03 72 72 .. 49 49 .. 3 99 .. 0.57 2 ? 14.7 0.3 3.3e-05 0.044 16 62 .. 100 145 .. 90 159 .. 0.74 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1.1 Aida_N 72 s 72 + FUN_000564-T1 49 A 49 2 PP == domain 2 score: 14.7 bits; conditional E-value: 3.3e-05 Aida_N 16 sWGqlveAideYeklakeikkavesqkkdltedqkklilkiavalel 62 + Gq+ e id+Y+kl+ke+k+ + k +l++ + k+++ + + l++ FUN_000564-T1 100 AIGQVREEIDKYSKLQKEVKQRNDVLKGRLEKRE-KIVTGLKTKLTM 145 66*******************9999666665554.555555544443 PP >> RUNDC1 RUN domain-containing protein 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 3.5 0.57 7.7e+02 35 87 .. 7 57 .. 1 65 [. 0.49 2 ? 12.3 8.9 0.00019 0.26 8 93 .. 23 109 .. 16 112 .. 0.78 3 ? 5.6 0.6 0.024 32 61 95 .. 112 146 .. 106 149 .. 0.85 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.57 RUNDC1 35 ekqkvvideLkeklnleldeleklseeelk...kqvdeaikqlvnplkvkeqlveq 87 +q+ i+e +++l l + ++ ++ + ++ i++l ++l k++l+++ FUN_000564-T1 7 RQQERTIQENRQELLLL-----EKNKVDIMnevARANHEIDELKTRLARKDNLLKH 57 33333333333333222.....2222222200034567788888888888888765 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00019 RUNDC1 8 qLksqledLekfayeegeaelpqsellekqkvvi..deLkeklnleldeleklseeelkkqvdeaikqlvnplkvkeqlveqLktqie 93 k++++ +++ a +++e + ++ l k +++ + L++ l l+ + + ++e+l+++ d+ i+++ ++l+vke+ + q++ +i FUN_000564-T1 23 LEKNKVDIMNEVARANHEIDELKTRLARKDNLLKhsQDLQDTLLLQAE-KLRFEKEQLNQRCDNVINEMQERLRVKENAIGQVREEID 109 457788888888888888865566666666655322568999999984.66899*****************************99885 PP == domain 3 score: 5.6 bits; conditional E-value: 0.024 RUNDC1 61 eelkkqvdeaikqlvnplkvkeqlveqLktqieDL 95 ++l+k+v + + l +l+ +e++v+ Lkt+++ L FUN_000564-T1 112 SKLQKEVKQRNDVLKGRLEKREKIVTGLKTKLTML 146 57899999999999999*************98755 PP >> CT398_CC CT398-like coiled coil hairpin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 18.1 0.00023 0.31 25 148 .. 7 131 .. 2 148 .. 0.69 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00023 CT398_CC 25 eeleaelaalrdelvaaetaveDldrevakaEadveqVraRaeRDrkrldsGa....vsaKdleaLqhElesLarRqseLEdeeLevMErreaaea 116 ++ e+ +++ r+el e + D+ eva+a++++++ ++R +R ++l++++ + ++e+L E e+L++R ++ +e e + +e+a FUN_000564-T1 7 RQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDNLLKHSQdlqdTLLLQAEKLRFEKEQLNQRCDNVINEMQERLRVKENAIG 102 56778899999****************************************984212233577788888888888876666555555555555555 PP CT398_CC 117 elaaaeaeleeaeaelaeaearrdaalaeida 148 +++++ ++ +++++e+++ + d ++++ FUN_000564-T1 103 QVREEIDKYSKLQKEVKQRN---DVLKGRLEK 131 55555555555555554433...433333333 PP >> Exonuc_VII_L Exonuclease VII, large subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 16.1 0.00029 0.39 153 272 .. 2 114 .. 1 151 [. 0.86 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00029 Exonuc_VII_L 153 ekrleralkrrlerkrqrlerlarrlksperlleqqrqrldeleerleralkrkleekrerleelearleraspeerleeakerlealkerlkral 248 +k++ r+ +r+++++rq+l l+++ + + ++++++++del++rl r k++l +++++l+ + l ++e+l+ +ke+l+++ +++ +++ FUN_000564-T1 2 KKTILRQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLAR--KDNLLKHSQDLQDTL-LL----QAEKLRFEKEQLNQRCDNVINEM 90 56778889999999*****999999999999****************99..677777777777776.23....35788888899999999999999 PP Exonuc_VII_L 249 krklekkkerlealaaklealspl 272 +++l+ k++++ ++ ++++++s l FUN_000564-T1 91 QERLRVKENAIGQVREEIDKYSKL 114 999999999999999999998875 PP >> Med28 Mediator complex subunit 28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 3.1 0.0011 1.5 68 93 .. 35 60 .. 2 64 .. 0.80 2 ? 8.1 2.6 0.0037 5 57 100 .. 70 113 .. 58 115 .. 0.85 3 ? 4.2 1.1 0.06 81 65 96 .. 113 144 .. 109 149 .. 0.87 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.0011 Med28 68 evlkeeieeLkaElerKdelikkhke 93 + ei+eLk+ l+rKd+l+k+ ++ FUN_000564-T1 35 ARANHEIDELKTRLARKDNLLKHSQD 60 45789****************98765 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0037 Med28 57 krlelsaqkpeevlkeeieeLkaElerKdelikkhkekieeWqs 100 ++l +++++ ++ + i+e+++ l+ K++ i + +e i+++++ FUN_000564-T1 70 EKLRFEKEQLNQRCDNVINEMQERLRVKENAIGQVREEIDKYSK 113 67788888888899999************************997 PP == domain 3 score: 4.2 bits; conditional E-value: 0.06 Med28 65 kpeevlkeeieeLkaElerKdelikkhkekie 96 k ++ +k+ ++ Lk le+++++++ k+k++ FUN_000564-T1 113 KLQKEVKQRNDVLKGRLEKREKIVTGLKTKLT 144 567889*******************9999986 PP >> TSNAXIP1_N Translin-associated factor X-interacting N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 4.6 0.016 22 57 101 .. 5 49 .. 3 62 .. 0.83 2 ? 11.2 2.9 0.00035 0.48 2 83 .. 70 154 .. 69 159 .. 0.87 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.016 TSNAXIP1_N 57 eLlesqrelqylkaklkgleesstkkaleleekreeiralekesk 101 +L+++ r+ q +++l +le++ + +e+ ++++ei +l++ FUN_000564-T1 5 ILRQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLA 49 799999999999****************************98643 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00035 TSNAXIP1_N 2 kkleqelqklkctkdg...pqekrlqvyrevFedlieeftiykdlLseIKnEYelylaeLlesqrelqylkaklkgleesstkka 83 +kl+ e ++l++ +d+ + ++rl v +++ ++ ee y +l++e+K+ + L+++ + + lk+kl+ l + +++a FUN_000564-T1 70 EKLRFEKEQLNQRCDNvinEMQERLRVKENAIGQVREEIDKYSKLQKEVKQRNDVLKGRLEKREKIVTGLKTKLTMLTTWNVRSA 154 68999999999888878889999*******************************9999999999999999999988877666655 PP >> SHE3 SWI5-dependent HO expression protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 14.4 0.00047 0.63 33 104 .. 20 91 .. 2 99 .. 0.81 2 ? 3.4 2.5 0.055 74 62 113 .. 95 146 .. 87 152 .. 0.73 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00047 SHE3 33 lelaqkkedkfleqlaslkhENdnLsallkRKerrvkdlekelseLkesveeltlskkqlkkrlenssaset 104 l l +k + ++++a + hE d L + l RK+ +k ++ + L + e+l +k+ql++r++n ++ + FUN_000564-T1 20 LLLLEKNKVDIMNEVARANHEIDELKTRLARKDNLLKHSQDLQDTLLLQAEKLRFEKEQLNQRCDNVINEMQ 91 334566677899***************************99999*********************9887655 PP == domain 2 score: 3.4 bits; conditional E-value: 0.055 SHE3 62 kRKerrvkdlekelseLkesveeltlskkqlkkrlenssaseteleeelerl 113 + Ke + ++ +e+++ ++ e+++++++lk rle+ ++ t l+ +l +l FUN_000564-T1 95 RVKENAIGQVREEIDKYSKLQKEVKQRNDVLKGRLEKREKIVTGLKTKLTML 146 4567777777777777777777888888888888888888888888887776 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.9 0.1 1.4e+02 75 119 .. 6 50 .. 2 53 .. 0.85 2 ? 12.4 5.7 0.00012 0.17 36 112 .. 51 127 .. 48 148 .. 0.79 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.1 DUF1664 75 ldeqkeiskeikeevtevredvsnikedvksvkeaveglesklke 119 l +q+++++e ++e+ ++++ +i ++v ++ + +l+++l++ FUN_000564-T1 6 LRQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLAR 50 567888899999999999999999999999999999999988865 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00012 DUF1664 36 krnlsdavesvskqleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveg 112 k nl + +++ l e+l+ K++L+qr d+v ++++e +++++ +v e ++ s+++++vk+ +++++g FUN_000564-T1 51 KDNLLKHSQDLQDTLLLQAEKLRFEKEQLNQRCDNVINEMQERLRVKENAIGQVREEIDKYSKLQKEVKQRNDVLKG 127 55677777778888888889****************99999999999988777777777777777777776665543 PP >> TPH Trichohyalin-plectin-homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 7.5 0.0052 7 101 151 .. 3 53 .. 2 57 .. 0.92 2 ? 8.0 15.5 0.00094 1.3 74 148 .. 50 124 .. 45 142 .. 0.85 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0052 TPH 101 eqmdeivekiqeedeaeaeekkekqkklreeidefneeqkelkelekeeek 151 + +++++e+ +e ++e + ++++ +++e++++n e elk + +++++ FUN_000564-T1 3 KTILRQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDN 53 67899**************************************99988876 PP == domain 2 score: 8.0 bits; conditional E-value: 0.00094 TPH 74 grqeLeeQieereqkrqeeaeekleEreqmdeivekiqeedeaeaeekkekqkklreeidefneeqkelkeleke 148 ++ L + ++ + +++ae+ + E+eq+++ ++ e +++ + k++ ++reeid++ ++qke k+++ FUN_000564-T1 50 RKDNLLKHSQDLQDTLLLQAEKLRFEKEQLNQRCDNVINEMQERLRVKENAIGQVREEIDKYSKLQKEVKQRNDV 124 5666777777777777888888888**********************************************9765 PP >> DUF4094 Domain of unknown function (DUF4094) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 1.7 0.0019 2.5 38 78 .. 8 49 .. 1 61 [. 0.72 2 ? 5.4 3.1 0.026 35 37 80 .. 95 146 .. 55 149 .. 0.70 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0019 DUF4094 38 qelklvsedcds.kkkesrskdilgevsktheaiqtLdktis 78 q+ ++++e+ ++ e+++ di++ev +++++i L+ +++ FUN_000564-T1 8 QQERTIQENRQElLLLEKNKVDIMNEVARANHEIDELKTRLA 49 444555655555544555567****************88876 PP == domain 2 score: 5.4 bits; conditional E-value: 0.026 DUF4094 37 k.qelkl..vsedcds....kkkesrskdilg.evsktheaiqtLdktissL 80 + +e + v+e+ d+ +k+ ++++d+l+ + +k+++ ++ L+ ++ +L FUN_000564-T1 95 RvKENAIgqVREEIDKysklQKEVKQRNDVLKgRLEKREKIVTGLKTKLTML 146 2323333346677776655544444577999999999999999998888877 PP >> DUF641 Plant protein of unknown function (DUF641) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 3.0 0.0064 8.6 75 119 .. 9 53 .. 2 61 .. 0.88 2 ? 8.2 5.3 0.0032 4.3 80 127 .] 74 121 .. 51 121 .. 0.79 3 ? -0.3 0.0 1.4 1.9e+03 96 119 .. 125 148 .. 122 154 .. 0.80 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0064 DUF641 75 leaeiqeqrsllktyeivvkkleselkakdseieeLrekLeeaer 119 e+ iqe+r+ l +e+ ++ +e+ + + ei+eL+ +L++ + FUN_000564-T1 9 QERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDN 53 57789***********************************98765 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0032 DUF641 80 qeqrsllktyeivvkkleselkakdseieeLrekLeeaerknkklekr 127 e+ +l + + v++++++ l+ k++ i ++re++++ ++ +k++++r FUN_000564-T1 74 FEKEQLNQRCDNVINEMQERLRVKENAIGQVREEIDKYSKLQKEVKQR 121 346678888999****************************99998876 PP == domain 3 score: -0.3 bits; conditional E-value: 1.4 DUF641 96 leselkakdseieeLrekLeeaer 119 l+ l+++++ ++ L+ kL+ ++ FUN_000564-T1 125 LKGRLEKREKIVTGLKTKLTMLTT 148 677889999999999999987765 PP >> DUF745 Protein of unknown function (DUF745) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 5.1 0.051 69 96 164 .. 10 78 .. 2 86 .. 0.81 2 ? 8.5 7.6 0.0016 2.2 68 157 .. 38 131 .. 34 142 .. 0.80 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.051 DUF745 96 qkaakqaqqqlealkallkaakenlenaeqvaaeaqqelaektqlleaAkkRveelekqlaearedlek 164 +++ ++ +q+l l++ + +++++a++ +e ++ la k +ll++++ ++l q ++ r + e+ FUN_000564-T1 10 ERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDNLLKHSQDLQDTLLLQAEKLRFEKEQ 78 667788888888898888888889999999999999999999999999999999999888887766655 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0016 DUF745 68 eqelreaeavvqeekeslqsseanakaaqkaak....qaqqqlealkallkaakenlenaeqvaaeaqqelaektqlleaAkkRveelekqlae 157 ++e+ e ++ + ++ + l++s+ ++ a+ + +q ++ +++++++e+l+ e++ ++ +e+++ ++l ++ k+R + l+ +l++ FUN_000564-T1 38 NHEIDELKTRLARKDNLLKHSQDLQDTLLLQAEklrfEKEQLNQRCDNVINEMQERLRVKENAIGQVREEIDKYSKLQKEVKQRNDVLKGRLEK 131 6889999999999999999999877765555550000555555666789999*************************************99987 PP >> KIF9 Kinesin-like protein KIF9 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 18.2 0.004 5.4 15 122 .. 8 121 .. 3 124 .. 0.80 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.004 KIF9 15 gseeiieenKaiLkerykeakelgeevneakneidelkekleqkreeraaqg.esen.....eegeveideeeeelikkleeekkeYkeafeeLkd 104 ++e++i+en++ L k+ ++ +ev a +eidelk++l +k + ++ + +++ e+ + e+++ +++ + ++e +++ + + + + FUN_000564-T1 8 QQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDNLLKHSQdLQDTlllqaEKLRFEKEQLNQRCDNVINEMQERLRVKENAIGQ 103 6788************************************987654433222022222221155556666677788889***************** PP KIF9 105 lKaeiehlqhlleqarvk 122 +++ei+++ +l ++ +++ FUN_000564-T1 104 VREEIDKYSKLQKEVKQR 121 ***********9999987 PP >> TMF_TATA_bd TATA element modulatory factor 1 TATA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 9.6 0.017 23 21 78 .. 6 63 .. 1 81 [. 0.91 2 ? 5.8 5.5 0.015 21 12 48 .. 85 121 .. 75 152 .. 0.77 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.017 TMF_TATA_bd 21 irrlegElaslkeelarleaerdeareEivklmkeneelkelkkeleelekelkelee 78 +r+ e ++ ++el le+++ ++ +E+ + e +elk+ ++ ++l k+ ++l++ FUN_000564-T1 6 LRQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDNLLKHSQDLQD 63 79****************************************************9986 PP == domain 2 score: 5.8 bits; conditional E-value: 0.015 TMF_TATA_bd 12 qlverlsseirrlegElaslkeelarleaerdeareE 48 ++++++++++r +e+ + +++ee+ + ++ ++e+++ FUN_000564-T1 85 NVINEMQERLRVKENAIGQVREEIDKYSKLQKEVKQR 121 67999*****************999999988887663 PP >> FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalytic domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 13.9 0.0064 8.6 61 171 .. 12 141 .. 2 160 .] 0.55 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0064 FUT8_N_cat 61 elke......llekrleeseeekkkaeeklksleekleka......kekleeakkskknelsleyEvlrrrleneikElwyllsselk...klkke 141 +++e llek+ + ++e +a++++++l+ +l+++ +++l+++ ++++l e+E+l +r +n i+E+ l+ + + ++++e FUN_000564-T1 12 TIQEnrqellLLEKNKVDIMNEVARANHEIDELKTRLARKdnllkhSQDLQDTLLLQAEKLRFEKEQLNQRCDNVINEMQERLRVKENaigQVREE 107 2222222222333333333444444444555554444444222211677777778899999*************9999998887655511144555 PP FUT8_N_cat 142 ekee....elekeieellellaeqkrslladiek 171 +++ + k+ +++l+ e+++++++ +++ FUN_000564-T1 108 IDKYsklqKEVKQRNDVLKGRLEKREKIVTGLKT 141 4444533344555677888888887777766554 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 2.2 0.0044 5.9 21 68 .. 6 53 .. 3 65 .. 0.86 2 ? 4.1 0.7 0.056 76 36 79 .. 77 120 .. 59 127 .. 0.83 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0044 DUF948 21 llklkktldevnktleklekqldpllkettellaktnelledvnekle 68 l++ ++t++e ++ l lek+ +++++e+++ ++++el +++k + FUN_000564-T1 6 LRQQERTIQENRQELLLLEKNKVDIMNEVARANHEIDELKTRLARKDN 53 77889*********************************8887777754 PP == domain 2 score: 4.1 bits; conditional E-value: 0.056 DUF948 36 eklekqldpllkettellaktnelledvneklekvdpvfeavkd 79 e+l+++ d++++e++e l+ ++ +v+e+++k +++ ++vk+ FUN_000564-T1 77 EQLNQRCDNVINEMQERLRVKENAIGQVREEIDKYSKLQKEVKQ 120 67888999999999999988888888888888888888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3086 (0.120806); expected 510.9 (0.02) Passed bias filter: 759 (0.0297123); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 19 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 1548.49 // Query: FUN_000565-T1 [L=175] Description: FUN_000565 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 15.9 0.9 0.017 15.4 0.9 1.2 1 SMCHD1_S5 SMCHD1, ribosomal S5 domain 2-like domain 0.15 12.5 0.1 0.2 12.1 0.1 1.2 1 DUF501 Protein of unknown function (DUF501) Domain annotation for each model (and alignments): >> SMCHD1_S5 SMCHD1, ribosomal S5 domain 2-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.9 1.4e-06 0.017 103 165 .. 19 82 .. 12 85 .. 0.68 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.4e-06 SMCHD1_S5 103 ecynRisgvlFtndkfqvstnKltfldlelklkkketiftrv..vngqeqrrkiekeFkeWlkec 165 +c + +gv+F+ ++ +vst K + e + k+++++ + + ++ ++ r+ keFk+Wl ++ FUN_000565-T1 19 SCPEESQGVIFVLSHGKVSTWKKRVNREE-RKKQRKAVRKDYnrKKRKQGLRRKMKEFKRWLARF 82 5666779*****************99544.44444444333322333334556679******876 PP >> DUF501 Protein of unknown function (DUF501) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 1.6e-05 0.2 28 93 .. 13 77 .. 4 97 .. 0.83 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 1.6e-05 DUF501 28 ptlfwLtcPelvkavsrLEaeglikaleeklaedeelaeayeaaheeyaakReellseeereelee 93 +tl+ L+cPe ++ v + ++g +++++++++++e +++ +a+ ++y +k+++ + +++e+++ FUN_000565-T1 13 ATLILLSCPEESQGVIFVLSHGKVSTWKKRVNREERKKQR-KAVRKDYNRKKRKQGLRRKMKEFKR 77 7999**************************9988877666.5778888877777776666766654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (175 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1856 (0.0726561); expected 510.9 (0.02) Passed bias filter: 823 (0.0322177); expected 510.9 (0.02) Passed Vit filter: 93 (0.00364063); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1722.34 // Query: FUN_000566-T1 [L=90] Description: FUN_000566 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.05 13.5 1.0 0.059 13.2 1.0 1.1 1 SLATT_5 SMODS and SLOG-associating 2TM effector domain fami 3.1 8.8 10.5 3.7 8.5 10.5 1.1 1 Nop25 Nucleolar protein 12 (25kDa) Domain annotation for each model (and alignments): >> SLATT_5 SMODS and SLOG-associating 2TM effector domain family 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 1.0 4.6e-06 0.059 70 129 .. 9 80 .. 2 85 .. 0.78 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 4.6e-06 SLATT_5 70 iilSilvLvisllessknYkerAeklhecalelsrlynelqlll..........seedlkekyk...elskeY 129 + ++++++++s++e+s+ + + + ++ +l +++l ++l+ ++ +e+d ++k+ +l+++Y FUN_000566-T1 9 LSIAVFIVIASFYETSEAFIL-SLSTRRDQLRMEKLKRKLEEEKiarrmqaleqEEQDVQRKLRhlqKLVQKY 80 6789***************87.9999***************99999996655554444444444555566666 PP >> Nop25 Nucleolar protein 12 (25kDa) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 10.5 0.00029 3.7 38 83 .. 40 85 .. 33 89 .. 0.87 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00029 Nop25 38 qeeaekkareekieeRkelreerkkeleeqveevkellkeaeeeee 83 e++++k eeki+ R ++ e+ +++++++++++++l+++ +++++ FUN_000566-T1 40 MEKLKRKLEEEKIARRMQALEQEEQDVQRKLRHLQKLVQKYKAKSK 85 68999**********************************9877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (90 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3636 (0.142337); expected 510.9 (0.02) Passed bias filter: 1340 (0.0524564); expected 510.9 (0.02) Passed Vit filter: 148 (0.0057937); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.45s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 896.49 // Query: FUN_000567-T1 [L=119] Description: FUN_000567 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.3 0.1 0.22 11.7 0.1 1.3 1 CopK Copper resistance protein K Domain annotation for each model (and alignments): >> CopK Copper resistance protein K # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 8.6e-06 0.22 36 53 .. 43 60 .. 40 73 .. 0.77 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.6e-06 CopK 36 ylkeGkvmeTkDgkkiam 53 + G+ meT Dgkki++ FUN_000567-T1 43 IIAIGQQMETGDGKKIII 60 5678***********975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1060 (0.0414954); expected 510.9 (0.02) Passed bias filter: 611 (0.0239186); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1196.69 // Query: FUN_000568-T1 [L=327] Description: FUN_000568 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-39 134.3 0.0 4.4e-39 133.6 0.0 1.4 1 UEV UEV domain Domain annotation for each model (and alignments): >> UEV UEV domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 133.6 0.0 1.7e-43 4.4e-39 3 121 .] 22 140 .. 20 140 .. 0.98 Alignments for each domain: == domain 1 score: 133.6 bits; conditional E-value: 1.7e-43 UEV 3 kdvvkvlskfkslkpktevytfedgssklllnlkGtipvkykgatyniPvllwlldsyPveaPivfvkptaemvikknkhvdaeGrvylpyLeeWk 98 +d +++l++f+ l+p+ + +t++dg++ +ll l+G +pv+ +ga yniPv++wl +++P+ +P+v+vkpt++m i ++khvda+G+vy+pyL+eW+ FUN_000568-T1 22 QDCMRALHQFNYLTPERQKFTHNDGREVDLLALDGILPVHIRGARYNIPVCVWLQENHPYIPPLVYVKPTNNMGISVSKHVDANGKVYHPYLTEWT 117 8999******************************************************************************************** PP UEV 99 seksnlvklvqelaqvfeeepPl 121 ++ks+l l+q l+ f+ee+P+ FUN_000568-T1 118 YPKSDLAALLQLLSCIFTEESPV 140 **********************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (327 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 669 (0.0261891); expected 510.9 (0.02) Passed bias filter: 492 (0.0192601); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3196.48 // Query: FUN_000569-T1 [L=719] Description: FUN_000569 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-50 170.2 10.1 9.8e-50 169.7 10.1 1.2 1 RabGAP-TBC Rab-GTPase-TBC domain 4.5e-17 62.4 0.2 7.1e-17 61.7 0.2 1.3 1 PH_RBD Rab-binding domain (RBD) 5.3e-11 43.1 6.1 8.9e-11 42.3 6.1 1.3 1 RabGap-TBC_2 RabGAP TBC domain Domain annotation for each model (and alignments): >> RabGAP-TBC Rab-GTPase-TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 169.7 10.1 1.2e-53 9.8e-50 3 216 .] 321 548 .. 319 548 .. 0.95 Alignments for each domain: == domain 1 score: 169.7 bits; conditional E-value: 1.2e-53 RabGAP-TBC 3 lRgkvWklllgaek.............evkklkkeekkqeksskeeselekkeeseeeeqIekDvprtfp.hs.fsfkngegqesLrriLkaysiy 83 +R+ vW++llg++k ++++++ +k q++s+ + +e++ e +e + I+kDv rt + + +s+ n+++ +L+ iL++y++y FUN_000569-T1 321 IRKPVWQYLLGYKKygytapsqqfllqAKEEEYRTMKLQWQSMTQTQEKNFAEFRERKQLIDKDVARTDRqTDfYSEANHPNLTKLYDILLTYCMY 416 79**********99************88899999999*********************************5448889999**************** PP RabGAP-TBC 84 npdvgYcqGmnfivapllllyldeeeaFwcfvsLlekyklrdlytsdfpglkkalkvfeellkkklpklykhlkelgidlelfalkWfltlflref 179 n d+gY+qGm+++++p+l+++++e eaFwcfv ++ +kl +++ ++++g+k +l+++ llk +p+ y++l+e++ +++f+++W+l f ref FUN_000569-T1 417 NFDLGYVQGMSDLLSPILVVMENEVEAFWCFVGFM--EKLTHNFDENQEGMKAQLHQLTVLLKFIDPHFYSYLEEHDSGNMYFCFRWLLITFKREF 510 ******************9****************..9********************************************************** PP RabGAP-TBC 180 plslvlriwDvlllege.kvvllrvalailkllkeell 216 ++ ++ +w+ l+ ++ +++l v+lail ++++ ++ FUN_000569-T1 511 SFPDIMLLWETLWSQKLsPNYHLIVCLAILDMHRNVIM 548 **********66665557788*************9886 PP >> PH_RBD Rab-binding domain (RBD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.7 0.2 8.3e-21 7.1e-17 2 148 .. 18 189 .. 17 190 .. 0.81 Alignments for each domain: == domain 1 score: 61.7 bits; conditional E-value: 8.3e-21 PH_RBD 2 llygKnnVlveps.....dveesikGylslhekdksdvflkWtP......nqlmksssqsssa...ssdseelqspdgknqw...........swa 72 ++y ++V v++ + + i G + ++ek + + f+ W+P + +++ss s+ + +s++e+ ++a FUN_000569-T1 18 VVYCQDGVCVHTAvptatQFANIISGKVTVVEK-ENSSFVDWSPivneeeEFELESSAYSEWNlitQSKHEGD--------AdantskrkrrsKYA 104 89*********998888788899**********.66779*****87654322222222222212224444442........222334444566*** PP PH_RBD 73 invevkeliyiklhqkneesasyivlvtqdGvqlpplhFprGg..........hlllflsalesgllpvvrldpplsrskeklkll 148 i + el +ik++ ++++++ y v++ +dG+ lp+lhF++Gg ++ + +sa + +l+ v++ + +l++s+ +l+l+ FUN_000569-T1 105 IFFDTAELHSIKRSDPKLGWS-YAVFILKDGTTLPALHFHSGGiselirrlqrYIWITKSAHNHKLFVVTEDQSALKKSLDQLQLF 189 *********************.*************************************************999*******99998 PP >> RabGap-TBC_2 RabGAP TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.3 6.1 1.1e-14 8.9e-11 2 158 .. 404 562 .. 403 581 .. 0.85 Alignments for each domain: == domain 1 score: 42.3 bits; conditional E-value: 1.1e-14 RabGap-TBC_2 2 eslfkvlkaysLyDtevgYaqgllfiaaplllympee.eaFsllvkLlkkydlrelfipdmpglelrLyqferlledllpalaihLqrqgvkssmy 96 ++l+ +l +y +y + gY+qg++ + +p+l+ m++e eaF +v +++k l + f ++ +g++ +L+q++ ll+ + p+ + L+ + + FUN_000569-T1 404 TKLYDILLTYCMYNFDLGYVQGMSDLLSPILVVMENEvEAFWCFVGFMEK--LTHNFDENQEGMKAQLHQLTVLLKFIDPHFYSYLEEHDSGNMYF 497 589*******************************8665**********86..8999**********************************999999 PP RabGap-TBC_2 97 asqwfltlFaykfpldlvlRifDlviaeGleailrlai..allkkneekllk.llkldqllkfLk 158 + w+l F +f+ ++++ +++++ ++ l ++l++ a+l ++ +++ l + +lk+++ FUN_000569-T1 498 CFRWLLITFKREFSFPDIMLLWETLWSQKLSPNYHLIVclAILDMHRNVIMEnALGFTYILKYIN 562 *************************9999987777765114455555555541344555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (719 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 827 (0.0323742); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.42s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 6978.62 // Query: FUN_000570-T1 [L=996] Description: FUN_000570 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-40 135.3 19.4 3e-08 34.4 0.4 7.5 7 EF-hand_7 EF-hand domain pair 2.3e-21 77.1 2.1 0.019 16.3 0.0 6.3 6 EF-hand_11 EF-hand domain 8.9e-18 62.8 23.2 0.014 15.6 0.0 11.2 11 EF-hand_6 EF-hand domain 1.4e-15 56.1 18.7 0.03 14.3 0.0 10.5 11 EF-hand_1 EF hand domain 2.2e-11 43.8 9.9 0.0014 18.8 0.2 6.8 7 EF-hand_8 EF-hand domain pair 1.1e-06 29.1 0.1 0.0095 16.4 0.0 4.1 4 DUF5580 Family of unknown function (DUF5580) N-termin 0.00024 21.6 0.6 0.52 10.9 0.0 4.8 6 DUF5580_M Family of unknown function (DUF5580) middle d 0.00035 20.4 0.2 9 6.5 0.0 5.9 5 EF-hand_5 EF hand 0.0013 19.0 0.8 5 7.3 0.0 4.9 5 SPEF2_C SPEF2 C-terminal domain 0.0022 18.2 3.8 6.8 7.1 0.0 5.9 6 EF-hand_EFHB_C EFHB C-terminal EF-hand domain 0.0077 17.1 1.4 93 4.1 0.0 5.5 7 EF-hand_9 EF-hand domain Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 1.3e-05 0.031 3 66 .. 120 181 .. 118 182 .. 0.89 2 ! 5.9 0.0 0.0098 23 14 56 .. 271 311 .. 270 317 .. 0.87 3 ! 17.5 0.1 2.4e-06 0.0056 10 48 .. 409 445 .. 408 464 .. 0.87 4 ! 17.7 0.1 2e-06 0.0046 4 67 .] 514 577 .. 511 577 .. 0.94 5 ! 29.4 0.1 4.6e-10 1.1e-06 1 64 [. 654 715 .. 654 717 .. 0.96 6 ! 21.1 2.7 1.8e-07 0.00042 3 66 .. 817 878 .. 816 879 .. 0.93 7 ! 34.4 0.4 1.3e-11 3e-08 3 64 .. 932 991 .. 931 994 .. 0.96 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.3e-05 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 l++aF++ D g G+++++ + +l ++ l++e+++ l+k + ld G+i+fe F+ + FUN_000570-T1 120 GLRQAFRSNDPMGKGSVSRQAFVTILY--HLCGYLTPEQINGLLKRLGLDAQGTITFEKFVTHF 181 699******************877777..66666799***********************9876 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0098 EF-hand_7 14 dgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGr 56 d dG + + +lk +l+ +g+ + +ee+e++++ fD+++ G FUN_000570-T1 271 DVDGMVLKPQLKTALQ--FLGFQMYEEEFEKVWDRFDKTGLGA 311 5578888888999999..********************98665 PP == domain 3 score: 17.5 bits; conditional E-value: 2.4e-06 EF-hand_7 10 llDsdgdGyldveelkkllrkleegeplsdeeveelfke 48 ++D d +G++++++++k+l e + l+ eev+ +++ FUN_000570-T1 409 KYDPDSTGKITRDDFRKALS--EHHLQLRSEEVDNFLQR 445 69******************..9999*******998875 PP == domain 4 score: 17.7 bits; conditional E-value: 2e-06 EF-hand_7 4 lkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldk.dGrisfeEFlelys 67 l aFk+lD+d+ G + + ++k+ll++ + ++l+dee+ ++ + + + d i + EFlel+s FUN_000570-T1 514 LLGAFKQLDRDNLGVVKRYQFKDLLET-RFYIKLTDEELSSIARPLRANYtDALIPYAEFLELFS 577 6789***********************.******************9998689*********985 PP == domain 5 score: 29.4 bits; conditional E-value: 4.6e-10 EF-hand_7 1 eeklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFle 64 ++++++aF+ +D+ + G+l++ +++l++ ++g+++s e++ lf ++ +G i+feE+++ FUN_000570-T1 654 FQAIFKAFQGMDQIKKGFLSKGMFQRLFE--RYGVNFSSPEIDLLFSKLPSEANGFINFEELVQ 715 57899************************..******************************976 PP == domain 6 score: 21.1 bits; conditional E-value: 1.8e-07 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 +l+eaF + D+ + +ld +++k++lr + ++++d+e+ l ++fD k+ r+ + EFl+++ FUN_000570-T1 817 ELHEAFMKKDHGKVATLDFDDFKSVLR--RFCKDVTDDEILCLCQKFDRGKNFRVWYLEFLKYF 878 799************************..556667899************************98 PP == domain 7 score: 34.4 bits; conditional E-value: 1.3e-11 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFle 64 +l++ Fk++D g G+++v ++k ++ ++pl +e++ ++f fD + Gr+s+ EF++ FUN_000570-T1 932 ALRRSFKKIDIHGHGFVSVTDFKAAML--NFKFPLNEEDFFHIFSVFDENMKGRVSYVEFMK 991 799********************9999..9******************************98 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 8.3e-06 0.019 22 85 .. 121 184 .. 112 190 .. 0.92 2 ? 3.3 0.0 0.093 2.2e+02 19 75 .. 400 456 .. 384 471 .. 0.71 3 ! 11.4 0.0 0.00028 0.64 3 95 .. 495 589 .. 493 594 .. 0.86 4 ! 15.2 0.0 1.8e-05 0.041 7 94 .. 642 730 .. 637 739 .. 0.82 5 ! 9.2 0.0 0.0013 3 7 82 .. 803 878 .. 798 888 .. 0.92 6 ! 14.5 0.1 3e-05 0.069 7 81 .. 918 992 .. 913 996 .] 0.93 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 8.3e-06 EF-hand_11 22 ivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsie 85 + q f d + +vsr+ f +i lt eq++ l + l ++a+g + ++ f++++ + FUN_000570-T1 121 LRQAFRSNDPMGKGSVSRQAFVTILYHLCGYLTPEQINGLLKRLGLDAQGTITFEKFVTHFQDN 184 6799999***************************************************999765 PP == domain 2 score: 3.3 bits; conditional E-value: 0.093 EF-hand_11 19 yhaivqefenfdtlksntvsreefrai.ctrrvqiltdeqfdrlwselpvnakgrlky 75 y + ++d + ++r++fr + ++q l e+ d + + v+ + y FUN_000570-T1 400 YNRVLSSCCKYDPDSTGKITRDDFRKAlSEHHLQ-LRSEEVDNFLQRCSVQEGNMVPY 456 556666666788888999******9650555666.56677787777777665555555 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00028 EF-hand_11 3 adrdilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqi.ltdeqfdrlwselpvnakgrl.kyqdflsklsiervaatpmaag 95 + d a+l + s + a+ f+++d + v r +f+ + + r i ltde++ + l n l y +fl +s+ r + t ++g FUN_000570-T1 495 SAVDAEAKLLDIMQSDFLALLGAFKQLDRDNLGVVKRYQFKDLLETRFYIkLTDEELSSIARPLRANYTDALiPYAEFLELFSSSRETKTASTSG 589 56677889999999****************************9988887769**************97765428**********99888776666 PP == domain 4 score: 15.2 bits; conditional E-value: 1.8e-05 EF-hand_11 7 ilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsi.ervaatpmaa 94 + a l+ ++ ++ai + f+ +d +k +s+ f+ + +r ++ ++d l+s+lp +a+g +++++++ + v++ FUN_000570-T1 642 LFAVLRDLLTDRFQAIFKAFQGMDQIKKGFLSKGMFQRLFERYGVNFSSPEIDLLFSKLPSEANGFINFEELVQHSFLnYNVSSRETGE 730 56778889999*******************************999999999******************99876533202344444444 PP == domain 5 score: 9.2 bits; conditional E-value: 0.0013 EF-hand_11 7 ilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflskl 82 +l r++ v++++ + + f + d k t+ ++f+++ r + +td+++ l +++ + r+ y +fl + FUN_000570-T1 803 VLKRIKPQVCAKWSELHEAFMKKDHGKVATLDFDDFKSVLRRFCKDVTDDEILCLCQKFDRGKNFRVWYLEFLKYF 878 78899999*******************************************9999999999999999999998755 PP == domain 6 score: 14.5 bits; conditional E-value: 3e-05 EF-hand_11 7 ilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsk 81 +++++++ + s ++a+ + f+++d vs +f+a l +e+f ++s + n kgr+ y +f+ + FUN_000570-T1 918 VVSKIRNKMISDWKALRRSFKKIDIHGHGFVSVTDFKAAMLNFKFPLNEEDFFHIFSVFDENMKGRVSYVEFMKR 992 78999999*****************************9988888899*************************987 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.9 0.0 0.0082 19 2 27 .. 121 146 .. 120 165 .. 0.93 2 ? -3.4 0.0 8 1.9e+04 14 23 .. 169 178 .. 166 182 .. 0.76 3 ? -1.4 0.0 1.8 4.2e+03 14 30 .] 273 289 .. 269 289 .. 0.82 4 ? 1.8 0.2 0.16 3.8e+02 1 19 [. 296 314 .. 296 322 .. 0.83 5 ! 15.6 0.0 5.8e-06 0.014 8 27 .. 409 428 .. 406 432 .. 0.91 6 ! 11.8 0.1 0.0001 0.24 4 27 .. 516 539 .. 513 543 .. 0.90 7 ? 5.4 0.2 0.011 26 2 30 .] 657 685 .. 656 685 .. 0.90 8 ? 1.1 0.0 0.29 6.7e+02 13 24 .. 704 715 .. 693 716 .. 0.84 9 ? 2.6 0.2 0.094 2.2e+02 1 28 [. 817 844 .. 817 847 .. 0.83 10 ! 14.0 0.1 1.9e-05 0.044 2 27 .. 933 958 .. 932 961 .. 0.92 11 ! 9.2 0.2 0.00069 1.6 2 23 .. 969 990 .. 968 991 .. 0.90 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0082 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 lr+aF+ D g+G++s++ + +l FUN_000570-T1 121 LRQAFRSNDPMGKGSVSRQAFVTILY 146 89*****************9998885 PP == domain 2 score: -3.4 bits; conditional E-value: 8 EF-hand_6 14 dGyisleElr 23 G+i++e + FUN_000570-T1 169 QGTITFEKFV 178 6999999886 PP == domain 3 score: -1.4 bits; conditional E-value: 1.8 EF-hand_6 14 dGyisleElraalrslG 30 dG + + +l+ al++lG FUN_000570-T1 273 DGMVLKPQLKTALQFLG 289 789999999**999987 PP == domain 4 score: 1.8 bits; conditional E-value: 0.16 EF-hand_6 1 elreaFklfDkdgdGyisl 19 e+++++++fDk g G ++ FUN_000570-T1 296 EFEKVWDRFDKTGLGAVDS 314 6899*********999986 PP == domain 5 score: 15.6 bits; conditional E-value: 5.8e-06 EF-hand_6 8 lfDkdgdGyisleElraalr 27 ++D d +G+i+++++r+al+ FUN_000570-T1 409 KYDPDSTGKITRDDFRKALS 428 79****************98 PP == domain 6 score: 11.8 bits; conditional E-value: 0.0001 EF-hand_6 4 eaFklfDkdgdGyisleElraalr 27 aFk++D+d+ G + + +++++l+ FUN_000570-T1 516 GAFKQLDRDNLGVVKRYQFKDLLE 539 59********************97 PP == domain 7 score: 5.4 bits; conditional E-value: 0.011 EF-hand_6 2 lreaFklfDkdgdGyisleElraalrslG 30 + +aF+ +D+ ++G++s+ ++++++ +G FUN_000570-T1 657 IFKAFQGMDQIKKGFLSKGMFQRLFERYG 685 5689*******************998766 PP == domain 8 score: 1.1 bits; conditional E-value: 0.29 EF-hand_6 13 gdGyisleElra 24 +G+i++eEl + FUN_000570-T1 704 ANGFINFEELVQ 715 69*******976 PP == domain 9 score: 2.6 bits; conditional E-value: 0.094 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrs 28 el+eaF + D+ + ++++++++ +lr FUN_000570-T1 817 ELHEAFMKKDHGKVATLDFDDFKSVLRR 844 5778888888888889**********94 PP == domain 10 score: 14.0 bits; conditional E-value: 1.9e-05 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 lr+ Fk++D g G++s+ +++aa+ FUN_000570-T1 933 LRRSFKKIDIHGHGFVSVTDFKAAML 958 8999*******************985 PP == domain 11 score: 9.2 bits; conditional E-value: 0.00069 EF-hand_6 2 lreaFklfDkdgdGyisleElr 23 + ++F++fD + +G++s+ E++ FUN_000570-T1 969 FFHIFSVFDENMKGRVSYVEFM 990 6789****************97 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.14 3.2e+02 2 28 .. 121 147 .. 120 148 .. 0.89 2 ? -0.0 0.0 0.5 1.2e+03 12 25 .. 167 180 .. 157 183 .. 0.81 3 ? 1.5 0.1 0.17 3.9e+02 1 18 [. 296 313 .. 296 314 .. 0.87 4 ! 14.3 0.0 1.3e-05 0.03 8 27 .. 409 428 .. 406 430 .. 0.92 5 ? 5.1 0.0 0.012 27 5 27 .. 517 539 .. 514 541 .. 0.91 6 ? -3.5 0.0 6.3 1.5e+04 17 27 .. 567 577 .. 566 578 .. 0.79 7 ? 0.0 0.2 0.49 1.1e+03 3 27 .. 658 682 .. 656 684 .. 0.85 8 ! 9.1 0.0 0.00062 1.4 1 24 [. 692 715 .. 692 716 .. 0.89 9 ? 3.8 0.3 0.029 68 1 28 [. 817 844 .. 817 845 .. 0.83 10 ! 10.7 0.0 0.00019 0.44 2 26 .. 933 957 .. 932 960 .. 0.92 11 ! 10.6 0.3 0.00021 0.49 3 23 .. 970 990 .. 968 992 .. 0.89 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.14 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkk 28 l+++Fr D g G ++++ f+++l + FUN_000570-T1 121 LRQAFRSNDPMGKGSVSRQAFVTILYH 147 68999999999************9976 PP == domain 2 score: -0.0 bits; conditional E-value: 0.5 EF-hand_1 12 DgdGkIdfeEfkel 25 D G+I+fe f++ FUN_000570-T1 167 DAQGTITFEKFVTH 180 667******99875 PP == domain 3 score: 1.5 bits; conditional E-value: 0.17 EF-hand_1 1 elkeiFrefDkDgdGkId 18 e++++++ fDk g G +d FUN_000570-T1 296 EFEKVWDRFDKTGLGAVD 313 799********9988776 PP == domain 4 score: 14.3 bits; conditional E-value: 1.3e-05 EF-hand_1 8 efDkDgdGkIdfeEfkellk 27 ++D D GkI++++f+++l+ FUN_000570-T1 409 KYDPDSTGKITRDDFRKALS 428 79***************997 PP == domain 5 score: 5.1 bits; conditional E-value: 0.012 EF-hand_1 5 iFrefDkDgdGkIdfeEfkellk 27 +F+ +D+D+ G + + +fk+ll FUN_000570-T1 517 AFKQLDRDNLGVVKRYQFKDLLE 539 8*****************99986 PP == domain 6 score: -3.5 bits; conditional E-value: 6.3 EF-hand_1 17 IdfeEfkellk 27 I + Ef+el++ FUN_000570-T1 567 IPYAEFLELFS 577 66899*99986 PP == domain 7 score: 0.0 bits; conditional E-value: 0.49 EF-hand_1 3 keiFrefDkDgdGkIdfeEfkellk 27 ++F+ +D+ + G++++ f++l+ FUN_000570-T1 658 FKAFQGMDQIKKGFLSKGMFQRLFE 682 58999999999*****999999886 PP == domain 8 score: 9.1 bits; conditional E-value: 0.00062 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfke 24 e++ +F+++ +G+I+feE+++ FUN_000570-T1 692 EIDLLFSKLPSEANGFINFEELVQ 715 6788899999999*********86 PP == domain 9 score: 3.8 bits; conditional E-value: 0.029 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkk 28 el e+F++ D + ++df++fk++l++ FUN_000570-T1 817 ELHEAFMKKDHGKVATLDFDDFKSVLRR 844 5778888888888889*********997 PP == domain 10 score: 10.7 bits; conditional E-value: 0.00019 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkell 26 l++ F+++D g G+++ +fk+++ FUN_000570-T1 933 LRRSFKKIDIHGHGFVSVTDFKAAM 957 6889*******************99 PP == domain 11 score: 10.6 bits; conditional E-value: 0.00021 EF-hand_1 3 keiFrefDkDgdGkIdfeEfk 23 iF++fD + G++++ Ef+ FUN_000570-T1 970 FHIFSVFDENMKGRVSYVEFM 990 569*****************8 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.03 71 2 49 .. 133 179 .. 132 184 .. 0.80 2 ! 11.0 0.0 0.00016 0.38 1 29 [. 414 441 .. 414 446 .. 0.84 3 ! 6.1 0.0 0.0057 13 31 52 .. 518 539 .. 517 541 .. 0.91 4 ? -4.1 0.0 8.8 2.1e+04 26 34 .. 653 661 .. 645 662 .. 0.79 5 ? 3.2 0.0 0.046 1.1e+02 8 49 .. 675 715 .. 668 718 .. 0.79 6 ? 0.3 0.1 0.36 8.3e+02 5 15 .. 833 844 .. 831 863 .. 0.59 7 ! 18.8 0.2 6.1e-07 0.0014 5 48 .. 948 990 .. 944 994 .. 0.89 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.03 EF-hand_8 2 kgvItresLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeFcv 49 kg+++r +++il l g+ l+ ++++ l++ + +D G+i+fe F+ FUN_000570-T1 133 KGSVSRQAFVTILyHLCGY--LTPEQINGLLKRLGLDAQGTITFEKFVT 179 7888888999988665533..69999999999999999*******9986 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00016 EF-hand_8 1 ekgvItresLkrilalLglqd..lsedevdt 29 ++g+Itr++++++l + ++ l +evd FUN_000570-T1 414 STGKITRDDFRKAL---SEHHlqLRSEEVDN 441 68**********88...77777799999885 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0057 EF-hand_8 31 frefDtDgdGkisfeeFcvlle 52 f+ +D+D+ G+++ F++lle FUN_000570-T1 518 FKQLDRDNLGVVKRYQFKDLLE 539 8889***************998 PP == domain 4 score: -4.1 bits; conditional E-value: 8.8 EF-hand_8 26 evdtlfref 34 ++++f++f FUN_000570-T1 653 RFQAIFKAF 661 57999*999 PP == domain 5 score: 3.2 bits; conditional E-value: 0.046 EF-hand_8 8 esLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeFcv 49 + ++r + g++ +s e+d lf+ + + +G i+fee+++ FUN_000570-T1 675 GMFQRLFeRY-GVN-FSSPEIDLLFSKLPSEANGFINFEELVQ 715 5566655555.677.9999*********************986 PP == domain 6 score: 0.3 bits; conditional E-value: 0.36 EF-hand_8 5 ItresLkril.a 15 ++++++k+ l + FUN_000570-T1 833 LDFDDFKSVLrR 844 678888885533 PP == domain 7 score: 18.8 bits; conditional E-value: 6.1e-07 EF-hand_8 5 ItresLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeFc 48 +++ ++k ++ + + + l+e++++++f++fD++ +G +s eF+ FUN_000570-T1 948 VSVTDFKAAMlNF-KFP-LNEEDFFHIFSVFDENMKGRVSYVEFM 990 57899***99777.888.**********************99998 PP >> DUF5580 Family of unknown function (DUF5580) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0047 11 32 85 .. 410 462 .. 393 470 .. 0.87 2 ! 16.4 0.0 4.1e-06 0.0095 24 90 .. 656 723 .. 643 727 .. 0.81 3 ? -2.3 0.0 2.9 6.8e+03 63 83 .. 856 875 .. 852 881 .. 0.65 4 ? -0.5 0.0 0.79 1.8e+03 24 58 .. 932 966 .. 917 991 .. 0.82 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0047 DUF5580 32 ldPissGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkgspelvnyeklllf 85 dP s+G + + ++ + + h++ l+ v ++qr s ++ ++v y+k++ + FUN_000570-T1 410 YDPDSTGKITRDDFRKALSEHHLQLRSEEVDNFLQRCSV-QEGNMVPYKKIMDL 462 6***********************************886.5689******9853 PP == domain 2 score: 16.4 bits; conditional E-value: 4.1e-06 DUF5580 24 klqkelkildPissGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkgspelvnyeklll..flkaaa 90 + k ++ +d i Gfl + ++rlf r+ v + P + ll+ ++ + +n+e+l+ fl+ + FUN_000570-T1 656 AIFKAFQGMDQIKKGFLSKGMFQRLFERYGVNFSSPEIDLLFSKLPSEA-NGFINFEELVQhsFLNYNV 723 45567788************************************98665.5799**9998533666655 PP == domain 3 score: -2.3 bits; conditional E-value: 2.9 DUF5580 63 llcqrfsrkgspelvnyekll 83 lcq+f r ++ + v y ++l FUN_000570-T1 856 CLCQKFDRGKNFR-VWYLEFL 875 69****9877654.4554433 PP == domain 4 score: -0.5 bits; conditional E-value: 0.79 DUF5580 24 klqkelkildPissGfllqsqlsrlflrhevPlql 58 l++ +k +d Gf+ +++ +l ++ Pl+ FUN_000570-T1 932 ALRRSFKKIDIHGHGFVSVTDFKAAMLNFKFPLNE 966 688899999*9*********************975 PP >> DUF5580_M Family of unknown function (DUF5580) middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 8.9 2.1e+04 32 54 .. 55 77 .. 34 78 .. 0.71 2 ! 10.9 0.0 0.00022 0.52 19 82 .. 118 181 .. 111 189 .. 0.93 3 ? 3.0 0.0 0.066 1.5e+02 23 85 .. 404 467 .. 386 475 .. 0.82 4 ? -0.5 0.0 0.78 1.8e+03 24 79 .. 659 714 .. 646 728 .. 0.77 5 ? -2.5 0.1 3.4 7.9e+03 21 45 .. 817 841 .. 804 862 .. 0.68 6 ? 0.2 0.0 0.49 1.1e+03 18 44 .. 929 955 .. 915 994 .. 0.84 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 8.9 DUF5580_M 32 sfsGlLpkpkvraiCgkhglylt 54 + G Lp+ + r+ +kh +lt FUN_000570-T1 55 QINGPLPQLRRRTKPQKHSRVLT 77 46799999999999999988876 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00022 DUF5580_M 19 lenLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvelL 82 + L+ +fr +D + G ++++ +i ylt+ +++ll+ l q+ i ++++v + FUN_000570-T1 118 ITGLRQAFRSNDPMGKGSVSRQAFVTILYHLCGYLTPEQINGLLKRLGLDAQGTITFEKFVTHF 181 667999***********************999****************************9765 PP == domain 3 score: 3.0 bits; conditional E-value: 0.066 DUF5580_M 23 nlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvel.Lsra 85 s k D +G +++ + r + h l+l ++ +l+ ++ +++ ++++++l L+r+ FUN_000570-T1 404 LSSCCKYDPDSTGKITRDDFRKALSEHHLQLRSEEVDNFLQRCSVQEGNMVPYKKIMDLfLDRS 467 456678899999*********999*********************************9736666 PP == domain 4 score: -0.5 bits; conditional E-value: 0.78 DUF5580_M 24 lsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlv 79 +f+ D+ G+L+k + + +++g+ ++ ++ l + + ++ i++++lv FUN_000570-T1 659 KAFQGMDQIKKGFLSKGMFQRLFERYGVNFSSPEIDLLFSKLPSEANGFINFEELV 714 67999999999999999999999999988887777777766666666666666665 PP == domain 5 score: -2.5 bits; conditional E-value: 3.4 DUF5580_M 21 nLnlsfrkeDrsfsGlLpkpkvrai 45 +L+ +f k+D+ +L + +++ FUN_000570-T1 817 ELHEAFMKKDHGKVATLDFDDFKSV 841 5666777777766666665555554 PP == domain 6 score: 0.2 bits; conditional E-value: 0.49 DUF5580_M 18 nlenLnlsfrkeDrsfsGlLpkpkvra 44 + + L++sf+k D G+++ ++ +a FUN_000570-T1 929 DWKALRRSFKKIDIHGHGFVSVTDFKA 955 67899********99999998887776 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.31 7.3e+02 14 23 .. 416 425 .. 410 428 .. 0.88 2 ? 0.0 0.1 0.43 1e+03 3 12 .. 517 525 .. 515 525 .. 0.84 3 ? 1.9 0.0 0.11 2.5e+02 13 23 .. 705 715 .. 704 719 .. 0.86 4 ? 1.7 0.0 0.12 2.9e+02 3 23 .. 935 955 .. 933 958 .. 0.84 5 ! 6.5 0.0 0.0039 9 4 22 .. 972 990 .. 971 992 .. 0.90 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.31 EF-hand_5 14 GkIskeELkr 23 GkI+++ +++ FUN_000570-T1 416 GKITRDDFRK 425 9*******98 PP == domain 2 score: 0.0 bits; conditional E-value: 0.43 EF-hand_5 3 dtFraiDlNg 12 + F+++D+++ FUN_000570-T1 517 A-FKQLDRDN 525 4.******95 PP == domain 3 score: 1.9 bits; conditional E-value: 0.11 EF-hand_5 13 DGkIskeELkr 23 +G+I++eEL + FUN_000570-T1 705 NGFINFEELVQ 715 6*******965 PP == domain 4 score: 1.7 bits; conditional E-value: 0.12 EF-hand_5 3 dtFraiDlNgDGkIskeELkr 23 F++iD g G++s+ +k+ FUN_000570-T1 935 RSFKKIDIHGHGFVSVTDFKA 955 45**************99997 PP == domain 5 score: 6.5 bits; conditional E-value: 0.0039 EF-hand_5 4 tFraiDlNgDGkIskeELk 22 +F +D N+ G++s E++ FUN_000570-T1 972 IFSVFDENMKGRVSYVEFM 990 59************99997 PP >> SPEF2_C SPEF2 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.43 1e+03 95 117 .. 121 143 .. 116 149 .. 0.83 2 ? -3.3 0.0 3.7 8.6e+03 2 34 .. 152 183 .. 151 190 .. 0.73 3 ? 0.9 0.0 0.2 4.6e+02 95 117 .. 403 425 .. 400 456 .. 0.92 4 ! 7.3 0.0 0.0022 5 89 117 .. 508 536 .. 504 584 .. 0.81 5 ? 3.6 0.0 0.029 68 95 124 .. 933 962 .. 918 991 .. 0.87 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.43 SPEF2_C 95 tlkrfkevDeestglitreqylq 117 +++ f++ D + g ++r+ + + FUN_000570-T1 121 LRQAFRSNDPMGKGSVSRQAFVT 143 68899999999999999999875 PP == domain 2 score: -3.3 bits; conditional E-value: 3.7 SPEF2_C 2 ftisqLenLvkqllevApsGliskkafiellqd 34 +t +q++ L k l A +G+i+ ++f+ +qd FUN_000570-T1 152 LTPEQINGLLKRLGLDA-QGTITFEKFVTHFQD 183 56778888888876554.788888889988888 PP == domain 3 score: 0.9 bits; conditional E-value: 0.2 SPEF2_C 95 tlkrfkevDeestglitreqylq 117 +l+++ ++D +stg itr+++ + FUN_000570-T1 403 VLSSCCKYDPDSTGKITRDDFRK 425 6788999**************87 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0022 SPEF2_C 89 qeeLLetlkrfkevDeestglitreqylq 117 q++ L++l fk++D ++ g+++r q+++ FUN_000570-T1 508 QSDFLALLGAFKQLDRDNLGVVKRYQFKD 536 6889***********************86 PP == domain 5 score: 3.6 bits; conditional E-value: 0.029 SPEF2_C 95 tlkrfkevDeestglitreqylqveLWFek 124 ++++fk++D ++ g+++ +++ + L F+ FUN_000570-T1 933 LRRSFKKIDIHGHGFVSVTDFKAAMLNFKF 962 7899*******************9998864 PP >> EF-hand_EFHB_C EFHB C-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0029 6.8 27 52 .. 280 305 .. 277 316 .. 0.79 2 ? 0.8 0.0 0.26 6e+02 41 73 .. 393 431 .. 385 433 .. 0.66 3 ? -3.3 0.0 5 1.2e+04 16 38 .. 539 561 .. 532 565 .. 0.74 4 ? 2.4 0.0 0.086 2e+02 26 50 .. 675 699 .. 672 712 .. 0.85 5 ? 1.6 0.0 0.15 3.5e+02 54 71 .. 942 959 .. 908 963 .. 0.77 6 ? 0.5 0.1 0.32 7.4e+02 34 66 .. 959 990 .. 956 992 .. 0.84 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0029 EF-hand_EFHB_C 27 eirrifenigvklsdetFeeiWkeas 52 ++++ ++ g+++ +e+Fe++W++ FUN_000570-T1 280 QLKTALQFLGFQMYEEEFEKVWDRFD 305 667777788*************9874 PP == domain 2 score: 0.8 bits; conditional E-value: 0.26 EF-hand_EFHB_C 41 detFeeiWkeas....kkd..pkgevsvesFrnaldelq 73 e+F+e ++++ k+d ++g++ ++Fr+al e + FUN_000570-T1 393 SEKFKEGYNRVLssccKYDpdSTGKITRDDFRKALSEHH 431 566666666444222155444799***********9976 PP == domain 3 score: -3.3 bits; conditional E-value: 5 EF-hand_EFHB_C 16 erdffkpRskeeirrifenigvk 38 e+ f+++ + ee+ +i + + FUN_000570-T1 539 ETRFYIKLTDEELSSIARPLRAN 561 77799999999999998766555 PP == domain 4 score: 2.4 bits; conditional E-value: 0.086 EF-hand_EFHB_C 26 eeirrifenigvklsdetFeeiWke 50 +r+fe+ gv++s +++ ++ + FUN_000570-T1 675 GMFQRLFERYGVNFSSPEIDLLFSK 699 55689***********999999876 PP == domain 5 score: 1.6 bits; conditional E-value: 0.15 EF-hand_EFHB_C 54 kdpkgevsvesFrnalde 71 + +g vsv +F+ a+ + FUN_000570-T1 942 IHGHGFVSVTDFKAAMLN 959 47999*********9966 PP == domain 6 score: 0.5 bits; conditional E-value: 0.32 EF-hand_EFHB_C 34 nigvklsdetFeeiWkeaskkdpkgevsvesFr 66 n + l++e+F +i+ ++ kg+vs+ +F FUN_000570-T1 959 NFKFPLNEEDFFHIFSVFD-ENMKGRVSYVEFM 990 5678899999*99999887.57899***99997 PP >> EF-hand_9 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 1.9 4.4e+03 41 62 .. 125 145 .. 119 147 .. 0.83 2 ? 3.6 0.0 0.057 1.3e+02 41 61 .. 407 426 .. 389 430 .. 0.86 3 ? 1.6 0.0 0.23 5.4e+02 4 45 .. 518 559 .. 516 578 .. 0.76 4 ? -2.8 0.0 5.6 1.3e+04 32 48 .. 735 751 .. 731 758 .. 0.73 5 ? 4.1 0.0 0.04 93 48 64 .. 828 844 .. 816 846 .. 0.86 6 ? -3.2 0.0 7.6 1.8e+04 3 22 .. 936 955 .. 935 957 .. 0.80 7 ? -0.2 0.0 0.84 1.9e+03 4 16 .. 973 985 .. 971 990 .. 0.88 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.9 EF-hand_9 41 arelDPdgedatveldtFlrVm 62 r+ DP g+ ++v F+ ++ FUN_000570-T1 125 FRSNDPMGK-GSVSRQAFVTIL 145 5788*****.999999999886 PP == domain 2 score: 3.6 bits; conditional E-value: 0.057 EF-hand_9 41 arelDPdgedatveldtFlrV 61 +++DPd +++ d+F + FUN_000570-T1 407 CCKYDPDST-GKITRDDFRKA 426 689******.********875 PP == domain 3 score: 1.6 bits; conditional E-value: 0.23 EF-hand_9 4 FevcDtqktGeVpvskliayLravaaqdpqeleleelarelD 45 F+ D+++ G+V+ + +++L+ + ++ el + ar l FUN_000570-T1 518 FKQLDRDNLGVVKRYQFKDLLETRFYIKLTDEELSSIARPLR 559 8889*****************988777777777777777665 PP == domain 4 score: -2.8 bits; conditional E-value: 5.6 EF-hand_9 32 pqeleleelarelDPdg 48 + + l+e+a+++ P FUN_000570-T1 735 TLSHLLQEYAKSVVPRK 751 55678999*99987765 PP == domain 5 score: 4.1 bits; conditional E-value: 0.04 EF-hand_9 48 gedatveldtFlrVmrd 64 g+ at+++d+F+ V+r+ FUN_000570-T1 828 GKVATLDFDDFKSVLRR 844 5569***********97 PP == domain 6 score: -3.2 bits; conditional E-value: 7.6 EF-hand_9 3 tFevcDtqktGeVpvsklia 22 F+ D + G V v++ +a FUN_000570-T1 936 SFKKIDIHGHGFVSVTDFKA 955 58888999999999998775 PP == domain 7 score: -0.2 bits; conditional E-value: 0.84 EF-hand_9 4 FevcDtqktGeVp 16 F+v+D + G+V FUN_000570-T1 973 FSVFDENMKGRVS 985 9*********996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (996 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1103 (0.0431787); expected 510.9 (0.02) Passed bias filter: 735 (0.0287728); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.47u 0.37s 00:00:00.84 Elapsed: 00:00:00.43 # Mc/sec: 9314.73 // Query: FUN_000571-T1 [L=73] Description: FUN_000571 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-09 37.8 0.8 2.9e-09 37.6 0.8 1.0 1 EF-hand_7 EF-hand domain pair 5.3e-07 29.3 1.5 0.00089 19.3 0.1 2.2 2 EF-hand_6 EF-hand domain 2.8e-06 27.0 1.4 0.0095 15.9 0.0 2.2 2 EF-hand_1 EF hand domain 0.0027 17.9 1.2 0.0076 16.5 1.0 1.8 2 EF-hand_8 EF-hand domain pair ------ inclusion threshold ------ 0.099 14.0 0.2 0.11 13.8 0.2 1.0 1 EF-hand_11 EF-hand domain Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.6 0.8 5.8e-13 2.9e-09 3 64 .. 9 68 .. 8 71 .. 0.96 Alignments for each domain: == domain 1 score: 37.6 bits; conditional E-value: 5.8e-13 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFle 64 +l++ Fk++D g G+++v ++k ++ ++pl +e++ ++f fD + r+s+ EF++ FUN_000571-T1 9 ALRRSFKKIDIHGHGFVSVTDFKAAML--NFKFPLNEEDFFHIFSVFDENMKERVSYVEFMK 68 79*********************9999..9******************************98 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.1 1.8e-07 0.00089 2 27 .. 10 35 .. 9 38 .. 0.92 2 ! 9.4 0.2 0.00026 1.3 2 23 .. 46 67 .. 45 68 .. 0.90 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1.8e-07 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 lr+ Fk++D g G++s+ +++aa+ FUN_000571-T1 10 LRRSFKKIDIHGHGFVSVTDFKAAML 35 8999*******************986 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00026 EF-hand_6 2 lreaFklfDkdgdGyisleElr 23 + ++F++fD + + ++s+ E++ FUN_000571-T1 46 FFHIFSVFDENMKERVSYVEFM 67 6789****************97 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 1.9e-06 0.0095 2 26 .. 10 34 .. 9 37 .. 0.92 2 ! 10.1 0.5 0.00013 0.67 3 24 .. 47 68 .. 45 69 .. 0.89 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 1.9e-06 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkell 26 l++ F+++D g G+++ +fk+++ FUN_000571-T1 10 LRRSFKKIDIHGHGFVSVTDFKAAM 34 7899********************9 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00013 EF-hand_1 3 keiFrefDkDgdGkIdfeEfke 24 iF++fD + ++++ Ef++ FUN_000571-T1 47 FHIFSVFDENMKERVSYVEFMK 68 579*****************85 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.1 0.0 0.0053 27 31 51 .. 14 34 .. 13 36 .. 0.89 2 ! 16.5 1.0 1.5e-06 0.0076 5 47 .. 25 66 .. 21 70 .. 0.81 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0053 EF-hand_8 31 frefDtDgdGkisfeeFcvll 51 f+ +D+ g G +s ++F+ ++ FUN_000571-T1 14 FKKIDIHGHGFVSVTDFKAAM 34 7779*************9987 PP == domain 2 score: 16.5 bits; conditional E-value: 1.5e-06 EF-hand_8 5 ItresLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeF 47 +++ ++k ++ + + + l+e++++++f++fD++ + +s eF FUN_000571-T1 25 VSVTDFKAAMlNF-KFP-LNEEDFFHIFSVFDENMKERVSYVEF 66 6889****99777.888.**************997666665555 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.2 2.2e-05 0.11 16 81 .. 4 69 .. 2 73 .] 0.91 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 2.2e-05 EF-hand_11 16 ashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsk 81 s ++a+ + f+++d vs +f+a l +e+f ++s + n k r+ y +f+ + FUN_000571-T1 4 ISDWKALRRSFKKIDIHGHGFVSVTDFKAAMLNFKFPLNEEDFFHIFSVFDENMKERVSYVEFMKR 69 578899999*******************9988888889*************************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (73 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 665 (0.0260325); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.22u 0.41s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 743.88 // Query: FUN_000572-T1 [L=141] Description: FUN_000572 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-09 38.8 0.4 1.2e-09 38.8 0.4 1.6 2 EF-hand_7 EF-hand domain pair 1.3e-07 31.2 1.4 0.0032 17.6 0.1 2.3 2 EF-hand_6 EF-hand domain 3.9e-07 29.6 1.1 0.033 14.2 0.0 2.4 2 EF-hand_1 EF hand domain 5.1e-05 23.4 1.0 0.00012 22.2 0.8 1.7 2 EF-hand_8 EF-hand domain pair 0.0015 19.9 0.2 0.002 19.4 0.2 1.2 1 EF-hand_11 EF-hand domain 0.0034 17.3 0.0 0.79 9.8 0.0 2.3 2 EF-hand_5 EF hand ------ inclusion threshold ------ 0.17 12.0 0.1 3.7 7.7 0.0 2.2 2 EF_EFCAB10_C EFCAB10, C-terminal EF-hand Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 1.7 6.2e+03 57 66 .. 14 23 .. 12 24 .. 0.78 2 ! 38.8 0.4 3.4e-13 1.2e-09 3 64 .. 77 136 .. 76 139 .. 0.96 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 1.7 EF-hand_7 57 isfeEFlely 66 + + EFl+++ FUN_000572-T1 14 VWYLEFLKYF 23 66899*9997 PP == domain 2 score: 38.8 bits; conditional E-value: 3.4e-13 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFle 64 +l++ Fk++D g G+++v ++k ++ ++pl +e++ ++f fD + Gr+s+ EF++ FUN_000572-T1 77 ALRRSFKKIDIHGHGFVSVTDFKAAML--NFKFPLNEEDFFHIFSVFDENMKGRVSYVEFMK 136 79*********************9999..9******************************98 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.1 8.7e-07 0.0032 2 27 .. 78 103 .. 77 106 .. 0.92 2 ! 12.6 0.2 3.5e-05 0.13 2 23 .. 114 135 .. 113 136 .. 0.90 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 8.7e-07 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 lr+ Fk++D g G++s+ +++aa+ FUN_000572-T1 78 LRRSFKKIDIHGHGFVSVTDFKAAML 103 8999*******************985 PP == domain 2 score: 12.6 bits; conditional E-value: 3.5e-05 EF-hand_6 2 lreaFklfDkdgdGyisleElr 23 + ++F++fD + +G++s+ E++ FUN_000572-T1 114 FFHIFSVFDENMKGRVSYVEFM 135 6789****************97 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 9.1e-06 0.033 2 26 .. 78 102 .. 77 105 .. 0.92 2 ! 14.0 0.3 1.1e-05 0.04 3 23 .. 115 135 .. 113 137 .. 0.89 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 9.1e-06 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkell 26 l++ F+++D g G+++ +fk+++ FUN_000572-T1 78 LRRSFKKIDIHGHGFVSVTDFKAAM 102 7899********************9 PP == domain 2 score: 14.0 bits; conditional E-value: 1.1e-05 EF-hand_1 3 keiFrefDkDgdGkIdfeEfk 23 iF++fD + G++++ Ef+ FUN_000572-T1 115 FHIFSVFDENMKGRVSYVEFM 135 569*****************8 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.022 82 31 51 .. 82 102 .. 81 104 .. 0.89 2 ! 22.2 0.8 3.3e-08 0.00012 5 48 .. 93 135 .. 89 139 .. 0.89 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.022 EF-hand_8 31 frefDtDgdGkisfeeFcvll 51 f+ +D+ g G +s ++F+ ++ FUN_000572-T1 82 FKKIDIHGHGFVSVTDFKAAM 102 77799************9887 PP == domain 2 score: 22.2 bits; conditional E-value: 3.3e-08 EF-hand_8 5 ItresLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeFc 48 +++ ++k ++ + + + l+e++++++f++fD++ +G +s eF+ FUN_000572-T1 93 VSVTDFKAAMlNF-KFP-LNEEDFFHIFSVFDENMKGRVSYVEFM 135 68899***99777.888.**********************99998 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.2 5.5e-07 0.002 7 81 .. 63 137 .. 57 141 .] 0.92 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 5.5e-07 EF-hand_11 7 ilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsk 81 +++++++ + s ++a+ + f+++d vs +f+a l +e+f ++s + n kgr+ y +f+ + FUN_000572-T1 63 VVSKIRNQMISDWKALRRSFKKIDIHGHGFVSVTDFKAAMLNFKFPLNEEDFFHIFSVFDENMKGRVSYVEFMKR 137 678999*******************************9988888899*************************987 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.2 0.0 0.0065 24 3 23 .. 80 100 .. 78 103 .. 0.84 2 ! 9.8 0.0 0.00022 0.79 4 22 .. 117 135 .. 116 137 .. 0.90 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.0065 EF-hand_5 3 dtFraiDlNgDGkIskeELkr 23 F++iD g G++s+ +k+ FUN_000572-T1 80 RSFKKIDIHGHGFVSVTDFKA 100 45***************9997 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00022 EF-hand_5 4 tFraiDlNgDGkIskeELk 22 +F +D N+ G++s E++ FUN_000572-T1 117 IFSVFDENMKGRVSYVEFM 135 59************99997 PP >> EF_EFCAB10_C EFCAB10, C-terminal EF-hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.001 3.7 7 28 .. 82 103 .. 77 105 .. 0.87 2 ? 1.9 0.1 0.068 2.5e+02 5 23 .. 116 134 .. 112 137 .. 0.86 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.001 EF_EFCAB10_C 7 FemLDptgrGyItlaQYkeALk 28 F+ +D+ g+G+++++ +k A+ FUN_000572-T1 82 FKKIDIHGHGFVSVTDFKAAML 103 7778****************96 PP == domain 2 score: 1.9 bits; conditional E-value: 0.068 EF_EFCAB10_C 5 amFemLDptgrGyItlaQY 23 +F+++D + +G ++++ + FUN_000572-T1 116 HIFSVFDENMKGRVSYVEF 134 58************99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (141 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1415.57 // Query: FUN_000573-T1 [L=130] Description: FUN_000573 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0068 17.3 19.0 0.0095 16.9 19.0 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 19.0 3.7e-07 0.0095 2 81 .. 19 108 .. 18 109 .. 0.88 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 3.7e-07 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgd.....tqCvtttiklsgg..gkksslsvkgCspscpelnetseigsltvtesccqsdlCns 81 +++C +C + +s ++c++ + C + + Cv+ ++++sg ++k+ +s++ C+++ ++ ++ ++ + +t + +cc+s++Cns FUN_000573-T1 19 AIKCKNCISSESMEDCKEREesvDCDSVRigfvaDRCVKMSYEYSGVkgFVKTCYSKQLCEQGNEAFRNCKQVSGATCKLNCCDSNYCNS 108 679*************9999999**777678888*********9987778**********877777777777777**************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1415 (0.0553924); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1285.83 // Query: FUN_000573-T2 [L=130] Description: FUN_000573 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0095 16.9 18.7 0.013 16.4 18.7 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 18.7 5.2e-07 0.013 2 81 .. 19 108 .. 18 109 .. 0.88 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 5.2e-07 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgd.....tqCvtttiklsgg..gkksslsvkgCspscpelnetseigsltvtesccqsdlCns 81 +++C +C++++s ++c++ + C + + Cv+ ++++sg + k+ +s++ C+++ ++ ++ ++ + +t + +cc+s++Cns FUN_000573-T2 19 AIKCKNCVSYESMEDCKEREesvDCDSVRigfvaDRCVKMSYEYSGVkeFIKTCYSKQLCEQGNEAFRNCKQVSGATCKWNCCDSNYCNS 108 679*************9999999**777678888**********9888899*********877777777777777**************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1493 (0.0584459); expected 510.9 (0.02) Passed bias filter: 527 (0.0206303); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1312.68 // Query: FUN_000574-T1 [L=1254] Description: FUN_000574 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-36 124.4 11.6 4.4e-14 52.9 0.0 7.9 7 TPR_12 Tetratricopeptide repeat 7.1e-33 114.4 3.5 1.6e-16 60.9 0.1 5.5 5 TPR_NPHP3 Nephrocystin-3 TPR domain 1.9e-28 98.1 12.8 5.3e-06 26.7 0.0 8.6 8 TPR_10 Tetratricopeptide repeat 5.6e-24 82.7 11.3 1.9e-05 24.9 0.1 7.8 7 TPR_2 Tetratricopeptide repeat 4.6e-21 74.2 10.3 2.1e-07 30.9 0.1 7.9 8 TPR_1 Tetratricopeptide repeat 7.4e-16 57.4 8.8 0.0042 17.6 0.1 8.3 7 TPR_8 Tetratricopeptide repeat 2e-15 55.9 10.6 0.018 15.6 0.0 8.6 7 TPR_7 Tetratricopeptide repeat 1e-12 47.9 7.6 0.22 12.8 0.0 8.1 6 TPR_14 Tetratricopeptide repeat 1.5e-09 38.4 0.0 7.7e-09 36.1 0.0 2.3 1 DUF4062 Domain of unknown function (DUF4062) 1.2e-08 35.7 3.7 0.15 13.0 0.0 5.5 5 TPR_16 Tetratricopeptide repeat 1.5e-08 35.4 1.2 0.18 12.6 0.0 5.5 5 TPR_19 Tetratricopeptide repeat 1.7e-08 35.3 0.1 1.6e-07 32.2 0.0 2.4 2 NPHP3_N Nephrocystin 3, N-terminal 3.1e-08 34.2 1.6 11 7.5 0.1 6.6 5 TPR_6 Tetratricopeptide repeat 1.5e-07 32.6 0.0 4.2e-07 31.1 0.0 1.7 1 AAA_16 AAA ATPase domain 1.7e-07 31.7 0.0 4e-07 30.5 0.0 1.7 1 NACHT NACHT domain 4.1e-07 30.7 0.1 8.5e-07 29.7 0.1 1.5 1 NPHP3_hel Nephrocystin 3, helical domain 1.1e-06 29.5 0.0 4.4e-06 27.5 0.0 2.0 1 AAA_22 AAA domain 3.2e-06 27.5 0.4 30 5.7 0.0 6.5 6 TPR_17 Tetratricopeptide repeat 2.6e-05 24.7 0.0 0.035 14.6 0.0 3.8 3 NPHP3 Nephrocystin-3 domain 0.00013 22.1 2.6 0.094 12.7 0.0 3.4 3 RNPP_C RNPP family C-terminal domain 0.00031 21.1 0.0 0.0007 19.9 0.0 1.6 1 ATPase_2 ATPase domain predominantly from Archaea 0.00058 20.3 0.5 0.048 14.2 0.0 3.7 3 TPR_9 Tetratricopeptide repeat 0.0007 20.2 3.4 2.7 8.9 0.0 5.2 4 PPR PPR repeat 0.0015 18.9 0.1 5.2 7.4 0.0 3.7 3 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR dom 0.0026 17.5 0.1 1.4 8.6 0.0 2.6 2 DAP3 Mitochondrial ribosomal death-associated prote 0.0031 17.9 2.0 1.3 9.3 0.1 3.7 3 ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ------ inclusion threshold ------ 0.017 15.8 3.3 4.2 8.1 0.2 3.3 2 Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat 0.024 15.4 0.2 2.7 8.9 0.0 3.2 2 TPR_20 Tetratricopeptide repeat 0.027 15.3 2.5 10 7.0 0.0 4.5 3 ANAPC3 Anaphase-promoting complex, cyclosome, subunit 0.036 15.2 0.1 6 8.3 0.0 3.7 2 TPR_4 Tetratricopeptide repeat 0.053 14.1 0.0 3.3 8.4 0.0 3.6 3 PPR_2 PPR repeat family 0.066 13.0 0.1 1.2 8.9 0.0 2.7 3 TPR_MalT MalT-like TPR region 0.075 12.7 0.3 0.22 11.1 0.3 1.7 1 KAP_NTPase KAP family P-loop domain 0.1 12.6 0.2 0.63 10.1 0.0 2.5 2 SHNi-TPR SHNi-TPR 0.11 12.8 0.0 0.83 10.0 0.0 2.3 2 HAT_Syf1_M Pre-mRNA-splicing factor SYF1 middle HAT repea 0.11 13.3 0.8 5 8.0 0.1 3.8 4 ARM_TT21_5th TT21 fifth ARM repeats domain 0.13 12.7 0.1 0.34 11.4 0.1 1.7 1 AIPR_N Abortive infection phage resistance protein N- 0.19 12.0 1.7 8.4 6.7 0.0 4.1 5 TPR_11 TPR repeat Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.02 13 49 77 .] 775 803 .. 722 803 .. 0.81 2 ! 52.9 0.0 6.6e-17 4.4e-14 2 76 .. 815 889 .. 814 890 .. 0.97 3 ! 23.9 0.5 7.4e-08 5e-05 5 77 .] 903 976 .. 899 976 .. 0.93 4 ! 23.8 0.0 7.8e-08 5.3e-05 26 71 .. 967 1012 .. 959 1012 .. 0.93 5 ? 6.2 0.0 0.024 16 9 71 .. 1033 1053 .. 1025 1057 .. 0.57 6 ! 13.3 0.5 0.00015 0.098 5 76 .. 1165 1228 .. 1161 1229 .. 0.85 7 ? 6.5 0.1 0.02 14 8 50 .. 1202 1244 .. 1196 1247 .. 0.83 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.02 TPR_12 49 rnLgrlylalgdyeeAlelleqaleiaek 77 + L+ y +++++A+ l++++le++ek FUN_000574-T1 775 NSLACMYVDVEEFAKAEPLHKEVLEVREK 803 56888888889999999999999988875 PP == domain 2 score: 52.9 bits; conditional E-value: 6.6e-17 TPR_12 2 tatalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +at+ln+l+ +++++ ++deAle+++++lel++r+l p+h+l +l+n+g +y+ +g+++e + le+al+++e FUN_000574-T1 815 VATSLNGLGVLCYKTNKFDEALEYYNRCLELHRRSLPPTHHLIPDTLNNIGATYSSMGKWRECADVLEEALQLYE 889 7999*99*******************************************************************8 PP == domain 3 score: 23.9 bits; conditional E-value: 7.4e-08 TPR_12 5 alnnlAavlrrlgr..ydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +l+nlA+++ rl++ A++l+ +al+++++++G dh ++ ++l ++ +l+ d++ e +qa +i+ek FUN_000574-T1 903 TLLNLAMAYVRLDDtgSNRAESLYLRALDIRTKAYGRDHSDVGQTLLSYSAFLLRV-DPKRSAEVAKQAADIFEK 976 6779999999999977899**********************************999.**************9986 PP == domain 4 score: 23.8 bits; conditional E-value: 7.8e-08 TPR_12 26 lekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqa 71 ++a +++e+++G +h +t++al n + ++ ++++++eA+ +++++ FUN_000574-T1 967 AKQAADIFEKSFGLEHTNTLNALENVALAFATSKEFAEAHPYFKKS 1012 689****************************************986 PP == domain 5 score: 6.2 bits; conditional E-value: 0.024 TPR_12 9 lAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqa 71 +A ++yl g++eeA++l+e+ FUN_000574-T1 1033 MA------------------------------------------DYYLNNGHHEEARQLFERL 1053 45..........................................5555555555555555554 PP == domain 6 score: 13.3 bits; conditional E-value: 0.00015 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +l+nlA++++ ++y++A+ ++++ l+l+ p++ ++ n+gr + ++g+ +A+e+l + l+iae FUN_000574-T1 1165 ILHNLAMCHAFYKDYEKACVYFKELLRLQ-----PED---VAIGTNYGRMLALSGEVYKAIEQLTRTLKIAE 1228 788**************************.....664...55667889999999999999999999999987 PP == domain 7 score: 6.5 bits; conditional E-value: 0.02 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrn 50 n++ +l+ g+ +A+e l + l +ae +++ ++++++ FUN_000574-T1 1202 NYGRMLALSGEVYKAIEQLTRTLKIAEDKNEETLIEQINSYLK 1244 8999**********************98888777777777765 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.9 0.1 2.4e-19 1.6e-16 6 202 .. 613 835 .. 610 841 .. 0.76 2 ! 16.8 0.0 7.2e-06 0.0048 118 195 .. 835 913 .. 833 917 .. 0.87 3 ! 16.0 0.0 1.2e-05 0.0082 138 205 .. 898 967 .. 895 969 .. 0.81 4 ! 28.5 0.1 2e-09 1.3e-06 122 220 .. 926 1023 .. 919 1034 .. 0.87 5 ? 2.7 0.0 0.15 99 144 171 .. 1166 1193 .. 1147 1230 .. 0.86 Alignments for each domain: == domain 1 score: 60.9 bits; conditional E-value: 2.4e-19 TPR_NPHP3 6 eyfssklkpgk......vtlRvvdelPWLlkqtedkekLkecllnlsvfqrlyargrcaellsyWqyvgadksklakaYlnaikkledav...... 89 +yf+ kl++++ + Rv elPWLl ++++k++L +cl+ s+f l + ++ +l++yW+ g++ +++ + Y +++ + + FUN_000574-T1 613 QYFEGKLQEKNleytteIPQRVKMELPWLLDKAGEKDRLIKCLTTPSLFWALRSGEKDYDLIHYWNSTGIKGEEINSLYEKTVDDQLALLylkere 708 67766666544232223778*******************************************************999977665432222332222 PP TPR_NPHP3 90 egelt...lakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPD....hPlvarslhq....LagLyaqwgkfstaealykqaleiye.. 172 +g ++ ++ + l + +f d g ++ p L+ra+ + a + hP +a++ q La++y + ++f++ae l+k+ le+ e FUN_000574-T1 709 NGGQPinaVKMLHPLVYEIAQFQGDAGNMTAMEPFLNRAIKLLKFAHSEEeikyHPKIAETFCQmtnsLACMYVDVEEFAKAEPLHKEVLEVREkf 804 333331113444556666899999999999999999999998766544333334999998865433339**********************98822 PP TPR_NPHP3 173 .nayGsdhelvakelealallyqkqdkhdla 202 +++ +va+ l++l +l k +k+d a FUN_000574-T1 805 aDKWKDGWSSVATSLNGLGVLCYKTNKFDEA 835 246777899********************88 PP == domain 2 score: 16.8 bits; conditional E-value: 7.2e-06 TPR_NPHP3 118 alpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenay.Gsdhelvakelealallyqk 195 al+ +r Le+ +l P h l+ +l ++ y+ gk++ ++ ++al++ye+ay G+ + v l la+ y + FUN_000574-T1 835 ALEYYNRCLELHRRSLPPTHHLIPDTLNNIGATYSSMGKWRECADVLEEALQLYEDAYfGQLPPDVGGTLLNLAMAYVR 913 677789*************************************************996377777777777777777765 PP == domain 3 score: 16.0 bits; conditional E-value: 1.2e-05 TPR_NPHP3 138 PlvarslhqLagLyaqwgkf..staealykqaleiyenayGsdhelvakelealallyqkqdkhdlaepl 205 P v+ +l +La y + + + ae+ly +al+i +ayG dh v + l + +++ + d ae+ FUN_000574-T1 898 PDVGGTLLNLAMAYVRLDDTgsNRAESLYLRALDIRTKAYGRDHSDVGQTLLSYSAFLLRVDPKRSAEVA 967 567788888888888776542278*************************999999888888877777765 PP == domain 4 score: 28.5 bits; conditional E-value: 2e-09 TPR_NPHP3 122 LqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravairkk 215 raL+iR a Dh v+++l + + + ++ae + kqa +i+e+ +G +h+ + le +al + + + a+p k++ +r++ FUN_000574-T1 926 YLRALDIRTKAYGRDHSDVGQTLLSYSAFLLRVDPKRSAE-VAKQAADIFEKSFGLEHTNTLNALENVALAFATSKEFAEAHPYFKKSGVVRHR 1018 569*******************999988888887777776.68************************************************998 PP TPR_NPHP3 216 akksk 220 + +++ FUN_000574-T1 1019 KGQMN 1023 65544 PP == domain 5 score: 2.7 bits; conditional E-value: 0.15 TPR_NPHP3 144 lhqLagLyaqwgkfstaealykqaleiy 171 lh+La +a ++ +++a ++k+ l + FUN_000574-T1 1166 LHNLAMCHAFYKDYEKACVYFKELLRLQ 1193 8*********************988765 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 9.2e-06 0.0062 6 34 .. 775 803 .. 771 803 .. 0.95 2 ! 26.7 0.0 7.9e-09 5.3e-06 1 41 [. 815 855 .. 815 856 .. 0.96 3 ! 18.6 0.1 2.9e-06 0.002 4 35 .. 860 891 .. 859 892 .. 0.94 4 ! 19.8 0.2 1.2e-06 0.00081 4 42 .] 903 943 .. 900 943 .. 0.91 5 ? 0.2 0.0 1.8 1.2e+03 20 40 .. 962 982 .. 959 984 .. 0.84 6 ? 6.4 0.0 0.019 13 1 27 [. 985 1011 .. 985 1015 .. 0.96 7 ! 8.2 0.1 0.0055 3.7 8 30 .. 1033 1055 .. 1031 1056 .. 0.88 8 ? 0.2 0.1 1.8 1.2e+03 5 31 .. 1166 1192 .. 1165 1193 .. 0.88 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 9.2e-06 TPR_10 6 nnLanalraqgryeeAeelleealairer 34 n La+++ + +++ Ae l++e+l++re+ FUN_000574-T1 775 NSLACMYVDVEEFAKAEPLHKEVLEVREK 803 99*************************97 PP == domain 2 score: 26.7 bits; conditional E-value: 7.9e-09 TPR_10 1 tasslnnLanalraqgryeeAeelleealairervlGpdHP 41 +a+sln L+++ +++++++eA+e++ ++l++++r l p H FUN_000574-T1 815 VATSLNGLGVLCYKTNKFDEALEYYNRCLELHRRSLPPTHH 855 79**********************************99995 PP == domain 3 score: 18.6 bits; conditional E-value: 2.9e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 +lnn++++++++g++ e + leeal+++e + FUN_000574-T1 860 TLNNIGATYSSMGKWRECADVLEEALQLYEDA 891 8****************************966 PP == domain 4 score: 19.8 bits; conditional E-value: 1.2e-06 TPR_10 4 slnnLanalraqgry..eeAeelleealairervlGpdHPd 42 +l nLa+a+ ++ + ++Ae l+ +al+ir +++G+dH d FUN_000574-T1 903 TLLNLAMAYVRLDDTgsNRAESLYLRALDIRTKAYGRDHSD 943 8999*****9999986689********************76 PP == domain 5 score: 0.2 bits; conditional E-value: 1.8 TPR_10 20 eAeelleealairervlGpdH 40 ++ e +++a +i e+ +G +H FUN_000574-T1 962 RSAEVAKQAADIFEKSFGLEH 982 5667789*************9 PP == domain 6 score: 6.4 bits; conditional E-value: 0.019 TPR_10 1 tasslnnLanalraqgryeeAeellee 27 t+++l n a a ++++eA+ ++++ FUN_000574-T1 985 TLNALENVALAFATSKEFAEAHPYFKK 1011 899**********************98 PP == domain 7 score: 8.2 bits; conditional E-value: 0.0055 TPR_10 8 LanalraqgryeeAeelleeala 30 +a ++ ++g +eeA++l+e+ ++ FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVR 1055 6889***************9775 PP == domain 8 score: 0.2 bits; conditional E-value: 1.8 TPR_10 5 lnnLanalraqgryeeAeelleealai 31 l+nLa+ + ++ye A +++e l++ FUN_000574-T1 1166 LHNLAMCHAFYKDYEKACVYFKELLRL 1192 8999999999999********999875 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.1 2.9e-08 1.9e-05 2 31 .. 817 846 .. 816 849 .. 0.91 2 ! 16.6 0.0 1.3e-05 0.0087 2 33 .. 859 890 .. 858 891 .. 0.93 3 ? 0.0 0.0 2.6 1.8e+03 4 30 .. 904 932 .. 902 935 .. 0.75 4 ? 4.9 0.0 0.074 50 3 26 .. 988 1011 .. 987 1012 .. 0.92 5 ! 12.3 0.0 0.00032 0.21 7 29 .. 1033 1055 .. 1029 1057 .. 0.90 6 ! 19.4 0.2 1.7e-06 0.0011 3 34 .] 1165 1196 .. 1164 1196 .. 0.95 7 ? 3.9 0.0 0.15 1e+02 6 33 .. 1202 1229 .. 1201 1230 .. 0.92 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 2.9e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 l+ lG ++yk ++++eAle+y+++lel FUN_000574-T1 817 TSLNGLGVLCYKTNKFDEALEYYNRCLELH 846 57999***********************96 PP == domain 2 score: 16.6 bits; conditional E-value: 1.3e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldPn 33 + l+n G y +g++ e+++ +e+Al+l+++ FUN_000574-T1 859 DTLNNIGATYSSMGKWRECADVLEEALQLYED 890 689**************************986 PP == domain 3 score: 0.0 bits; conditional E-value: 2.6 TPR_2 4 lynlGlayyklgdy..eeAleayekAlel 30 l nl++ay +l d ++A+ +y +Al + FUN_000574-T1 904 LLNLAMAYVRLDDTgsNRAESLYLRALDI 932 67889999888887666777777777765 PP == domain 4 score: 4.9 bits; conditional E-value: 0.074 TPR_2 3 alynlGlayyklgdyeeAleayek 26 al n +la + +++++eA+ +++k FUN_000574-T1 988 ALENVALAFATSKEFAEAHPYFKK 1011 78899*****************98 PP == domain 5 score: 12.3 bits; conditional E-value: 0.00032 TPR_2 7 lGlayyklgdyeeAleayekAle 29 +++ y+++g++eeA++++e+ ++ FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVR 1055 6999****************876 PP == domain 6 score: 19.4 bits; conditional E-value: 1.7e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleldPnn 34 +l+nl+++++ +dye+A ++++ l+l+P++ FUN_000574-T1 1165 ILHNLAMCHAFYKDYEKACVYFKELLRLQPED 1196 589***************************86 PP == domain 7 score: 3.9 bits; conditional E-value: 0.15 TPR_2 6 nlGlayyklgdyeeAleayekAleldPn 33 n G+ ++ +g+ +A+e + + l+++++ FUN_000574-T1 1202 NYGRMLALSGEVYKAIEQLTRTLKIAED 1229 68999*******************9875 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.088 59 5 33 .. 775 803 .. 775 804 .. 0.91 2 ! 30.9 0.1 3.1e-10 2.1e-07 2 31 .. 817 846 .. 816 849 .. 0.92 3 ! 19.1 0.0 1.8e-06 0.0012 2 33 .. 859 890 .. 858 890 .. 0.94 4 ? -1.7 0.0 6.4 4.3e+03 4 15 .. 904 915 .. 903 917 .. 0.82 5 ? 2.1 0.0 0.41 2.7e+02 3 26 .. 988 1011 .. 987 1012 .. 0.89 6 ? 2.3 0.0 0.35 2.4e+02 9 26 .. 1035 1052 .. 1032 1055 .. 0.88 7 ! 12.8 0.4 0.00017 0.12 4 34 .] 1166 1196 .. 1164 1196 .. 0.94 8 ? -0.4 0.0 2.5 1.7e+03 11 33 .. 1207 1229 .. 1204 1230 .. 0.82 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.088 TPR_1 5 ynlGnayfklgkydeAleyyekALelnPn 33 + l+ +y +++ +A+ +++Le++++ FUN_000574-T1 775 NSLACMYVDVEEFAKAEPLHKEVLEVREK 803 57999********************9887 PP == domain 2 score: 30.9 bits; conditional E-value: 3.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +l++lG++++k +k+deAleyy+++Lel FUN_000574-T1 817 TSLNGLGVLCYKTNKFDEALEYYNRCLELH 846 679*************************96 PP == domain 3 score: 19.1 bits; conditional E-value: 1.8e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALelnPn 33 ++l+n+G++y ++gk+ e+ + e+AL+l+++ FUN_000574-T1 859 DTLNNIGATYSSMGKWRECADVLEEALQLYED 890 89***************************875 PP == domain 4 score: -1.7 bits; conditional E-value: 6.4 TPR_1 4 lynlGnayfklg 15 l nl++ay +l FUN_000574-T1 904 LLNLAMAYVRLD 915 78******8876 PP == domain 5 score: 2.1 bits; conditional E-value: 0.41 TPR_1 3 alynlGnayfklgkydeAleyyek 26 al n ++a+ +++ eA y++k FUN_000574-T1 988 ALENVALAFATSKEFAEAHPYFKK 1011 6668899***************99 PP == domain 6 score: 2.3 bits; conditional E-value: 0.35 TPR_1 9 nayfklgkydeAleyyek 26 y+++g ++eA + +e+ FUN_000574-T1 1035 DYYLNNGHHEEARQLFER 1052 569************997 PP == domain 7 score: 12.8 bits; conditional E-value: 0.00017 TPR_1 4 lynlGnayfklgkydeAleyyekALelnPnn 34 l nl++++ ++y++A y+++ L+l+P++ FUN_000574-T1 1166 LHNLAMCHAFYKDYEKACVYFKELLRLQPED 1196 78***************************86 PP == domain 8 score: -0.4 bits; conditional E-value: 2.5 TPR_1 11 yfklgkydeAleyyekALelnPn 33 + g+ +A+e + L++ ++ FUN_000574-T1 1207 LALSGEVYKAIEQLTRTLKIAED 1229 56678899**********99876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.17 1.1e+02 5 30 .. 725 750 .. 721 750 .. 0.92 2 ! 17.6 0.1 6.2e-06 0.0042 2 30 .. 817 845 .. 816 847 .. 0.93 3 ? 7.3 0.0 0.013 8.8 2 32 .. 859 889 .. 858 890 .. 0.92 4 ? 1.7 0.0 0.83 5.6e+02 4 30 .. 904 932 .. 902 935 .. 0.72 5 ? -0.8 0.0 5.1 3.4e+03 3 26 .. 988 1011 .. 986 1012 .. 0.87 6 ! 9.2 0.0 0.0031 2.1 7 29 .. 1033 1055 .. 1029 1058 .. 0.90 7 ! 13.7 0.1 0.00011 0.077 3 34 .] 1165 1196 .. 1164 1196 .. 0.94 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.17 TPR_8 5 ynlGliylklgdyeeAkeyyekalel 30 y +++ + g++ +++ ++++a++l FUN_000574-T1 725 YEIAQFQGDAGNMTAMEPFLNRAIKL 750 889999******************97 PP == domain 2 score: 17.6 bits; conditional E-value: 6.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +++ lG ++ k+++++eA eyy+++lel FUN_000574-T1 817 TSLNGLGVLCYKTNKFDEALEYYNRCLEL 845 67899**********************98 PP == domain 3 score: 7.3 bits; conditional E-value: 0.013 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 ++++n+G +y+++g+ e ++e+al+l + FUN_000574-T1 859 DTLNNIGATYSSMGKWRECADVLEEALQLYE 889 5789***********************9987 PP == domain 4 score: 1.7 bits; conditional E-value: 0.83 TPR_8 4 yynlGliylklgdy..eeAkeyyekalel 30 ++nl+++y +l d + A+ y +al++ FUN_000574-T1 904 LLNLAMAYVRLDDTgsNRAESLYLRALDI 932 789*******9996335666666666665 PP == domain 5 score: -0.8 bits; conditional E-value: 5.1 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 a+ n +l+ + ++++eA y++k FUN_000574-T1 988 ALENVALAFATSKEFAEAHPYFKK 1011 66788999999***********99 PP == domain 6 score: 9.2 bits; conditional E-value: 0.0031 TPR_8 7 lGliylklgdyeeAkeyyekale 29 +++ yl+ g +eeA++ +e+ ++ FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVR 1055 6899***************9987 PP == domain 7 score: 13.7 bits; conditional E-value: 0.00011 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldpdn 34 +++nl++++ +dye+A y+++ l+l+p++ FUN_000574-T1 1165 ILHNLAMCHAFYKDYEKACVYFKELLRLQPED 1196 589***************************85 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.0 0.0012 0.82 4 34 .. 776 806 .. 774 807 .. 0.91 2 ! 15.6 0.0 2.6e-05 0.018 1 30 [. 818 847 .. 818 852 .. 0.91 3 ! 12.4 0.1 0.00028 0.19 1 31 [. 860 890 .. 860 891 .. 0.94 4 ? 6.5 0.5 0.023 15 1 30 [. 903 934 .. 903 937 .. 0.84 5 ? 3.9 0.0 0.16 1e+02 6 27 .. 1034 1055 .. 1031 1058 .. 0.81 6 ? 4.3 0.0 0.11 74 2 35 .. 1166 1197 .. 1165 1198 .. 0.89 7 ? -0.9 0.0 5.1 3.4e+03 6 34 .. 1204 1232 .. 1202 1234 .. 0.85 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.0012 TPR_7 4 aLariyrklGdydeAirlyerlLalakdped 34 +La +y +++ +A++l++++L+++++ d FUN_000574-T1 776 SLACMYVDVEEFAKAEPLHKEVLEVREKFAD 806 69**********************9988766 PP == domain 2 score: 15.6 bits; conditional E-value: 2.6e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalak 30 +L L+ ++ k++++deA+++y r+L+l + FUN_000574-T1 818 SLNGLGVLCYKTNKFDEALEYYNRCLELHR 847 5789**********************9977 PP == domain 3 score: 12.4 bits; conditional E-value: 0.00028 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 +L +++ +y+++G+++e ++++e++L+l +d FUN_000574-T1 860 TLNNIGATYSSMGKWRECADVLEEALQLYED 890 689***********************99987 PP == domain 4 score: 6.5 bits; conditional E-value: 0.023 TPR_7 1 aLsaLariyrklGdy..deAirlyerlLalak 30 +L++La +y +l d +A++ly r+L+++ FUN_000574-T1 903 TLLNLAMAYVRLDDTgsNRAESLYLRALDIRT 934 699********77753389*******999875 PP == domain 5 score: 3.9 bits; conditional E-value: 0.16 TPR_7 6 ariyrklGdydeAirlyerlLa 27 a+ y + G +eA +l+erl + FUN_000574-T1 1034 ADYYLNNGHHEEARQLFERLVR 1055 666999*************543 PP == domain 6 score: 4.3 bits; conditional E-value: 0.11 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 L++La ++ dy++A+ ++++ l+ +ped+ FUN_000574-T1 1166 LHNLAMCHAFYKDYEKACVYFKE--LLRLQPEDV 1197 899999999999***********..888888886 PP == domain 7 score: -0.9 bits; conditional E-value: 5.1 TPR_7 6 ariyrklGdydeAirlyerlLalakdped 34 +r++ +G+ +Ai+ ++r L +a+d+++ FUN_000574-T1 1204 GRMLALSGEVYKAIEQLTRTLKIAEDKNE 1232 67788889999999999**9999999875 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 0.0 0.0016 1.1 7 34 .. 822 849 .. 818 857 .. 0.85 2 ? 6.7 0.0 0.032 21 8 34 .. 865 891 .. 858 895 .. 0.85 3 ! 12.8 0.0 0.00033 0.22 7 30 .. 1033 1056 .. 1029 1067 .. 0.89 4 ? 1.5 0.0 1.5 1e+03 16 42 .. 1144 1170 .. 1138 1172 .. 0.85 5 ! 12.5 0.0 0.0004 0.27 4 43 .. 1166 1205 .. 1163 1206 .. 0.91 6 ? 1.4 0.0 1.6 1.1e+03 7 32 .. 1203 1228 .. 1198 1239 .. 0.81 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.0016 TPR_14 7 larallalGdpdeAlelleralaldPdd 34 l+ ++ +++++deAle+++r+l+l+ + FUN_000574-T1 822 LGVLCYKTNKFDEALEYYNRCLELHRRS 849 67789999***************99766 PP == domain 2 score: 6.7 bits; conditional E-value: 0.032 TPR_14 8 arallalGdpdeAlelleralaldPdd 34 ++++ G++ e++++le+al+l+ d FUN_000574-T1 865 GATYSSMGKWRECADVLEEALQLYEDA 891 6788999***************99875 PP == domain 3 score: 12.8 bits; conditional E-value: 0.00033 TPR_14 7 larallalGdpdeAlelleralal 30 +a+++l++G+++eA++l+er++++ FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVRT 1056 799******************996 PP == domain 4 score: 1.5 bits; conditional E-value: 1.5 TPR_14 16 dpdeAlelleralaldPddpeawlala 42 + +e le++ a+a++P+d+ ++++la FUN_000574-T1 1144 HRKEGLEIIVIAHAKFPEDTIILHNLA 1170 567888888899************998 PP == domain 5 score: 12.5 bits; conditional E-value: 0.0004 TPR_14 4 wlalarallalGdpdeAlelleralaldPddpeawlalar 43 ++ la ++ +d+++A +++++l+l P+d ++ +++r FUN_000574-T1 1166 LHNLAMCHAFYKDYEKACVYFKELLRLQPEDVAIGTNYGR 1205 567999**************************99888877 PP == domain 6 score: 1.4 bits; conditional E-value: 1.6 TPR_14 7 larallalGdpdeAlelleralaldP 32 ++r l+ G+ +A+e l r l+ FUN_000574-T1 1203 YGRMLALSGEVYKAIEQLTRTLKIAE 1228 89999***************999643 PP >> DUF4062 Domain of unknown function (DUF4062) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.1 0.0 1.2e-11 7.7e-09 1 67 [. 13 93 .. 13 110 .. 0.77 Alignments for each domain: == domain 1 score: 36.1 bits; conditional E-value: 1.2e-11 DUF4062 1 kvFiSStfkdlkeeRealveallelglep...................vlmee...faasdesqlelclkeidecdvyvlilggrYGsi 67 +vF SS+f +l+eeRe+l++ p + +s++ ++e+cl+e d++d+ v+++g+rYG+ FUN_000574-T1 13 RVFFSSPFGGLEEEREELTKKYW-----PqlsslckkagyefvpvdmrW---GitsEMSSKAATIEICLREMDRSDMIVGFFGQRYGWH 93 7***************9998765.....111123445455556655443...0555999*****************************7 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 0.00023 0.15 7 58 .. 781 843 .. 776 848 .. 0.79 2 ? 0.6 0.1 1.7 1.1e+03 14 47 .. 882 917 .. 867 936 .. 0.59 3 ? -0.0 0.1 2.7 1.8e+03 32 55 .. 987 1010 .. 963 1012 .. 0.79 4 ! 10.4 0.1 0.0015 0.99 3 28 .. 1033 1061 .. 1032 1067 .. 0.81 5 ? 6.3 0.0 0.029 20 16 60 .. 1182 1226 .. 1177 1231 .. 0.85 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00023 TPR_16 7 alaagdyddAaaaleaalrrn...........PeaaaAllglGlallrqgrlaeAaaayraal 58 +++ ++++ A+++ +++l+ + + a+ l+glG++++++++++eA+++y++ l FUN_000574-T1 781 YVDVEEFAKAEPLHKEVLEVRekfadkwkdgwSSVATSLNGLGVLCYKTNKFDEALEYYNRCL 843 5666667777777777777777777777778888999**********************9955 PP == domain 2 score: 0.6 bits; conditional E-value: 1.7 TPR_16 14 ddAaaaleaalrrn..PeaaaAllglGlallrqgrl 47 ++A+ ++e a + P+ ll+l+ a+ r+ + FUN_000574-T1 882 EEALQLYEDAYFGQlpPDVGGTLLNLAMAYVRLDDT 917 334444444444446776666677777776666554 PP == domain 3 score: -0.0 bits; conditional E-value: 2.7 TPR_16 32 aAllglGlallrqgrlaeAaaayr 55 Al + +la++ +++aeA +++ FUN_000574-T1 987 NALENVALAFATSKEFAEAHPYFK 1010 58899999*******999977775 PP == domain 4 score: 10.4 bits; conditional E-value: 0.0015 TPR_16 3 laraalaagdyddAaaaleaalrrn...P 28 +a+++l +g+ ++A+ ++e+++r + FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVRTDfvsD 1061 699*******************9887543 PP == domain 5 score: 6.3 bits; conditional E-value: 0.029 TPR_16 16 AaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalra 60 A +++++lr +Pe++a+ ++G++l+ g++ +A++ + + l++ FUN_000574-T1 1182 ACVYFKELLRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTLKI 1226 55589*******************************888777655 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.15 1e+02 30 51 .. 821 842 .. 782 851 .. 0.74 2 ? 2.1 0.2 0.54 3.6e+02 8 40 .. 882 916 .. 878 929 .. 0.89 3 ! 9.9 0.0 0.002 1.3 29 57 .. 1031 1059 .. 997 1067 .. 0.69 4 ? 2.1 0.0 0.54 3.6e+02 17 44 .. 1155 1182 .. 1155 1182 .. 0.95 5 ! 12.6 0.0 0.00027 0.18 5 57 .. 1177 1229 .. 1176 1233 .. 0.94 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.15 TPR_19 30 lLArallalgrldeAealLaal 51 +L+ ++++++++deA + ++ FUN_000574-T1 821 GLGVLCYKTNKFDEALEYYNRC 842 7888999999999999888775 PP == domain 2 score: 2.1 bits; conditional E-value: 0.54 TPR_19 8 deAlalLeqal..aedPdnaearllLArallalgr 40 +eAl+l+e a+ ++ Pd +l+LA a+++l++ FUN_000574-T1 882 EEALQLYEDAYfgQLPPDVGGTLLNLAMAYVRLDD 916 79*******98778899999999999999998876 PP == domain 3 score: 9.9 bits; conditional E-value: 0.002 TPR_19 29 llLArallalgrldeAealLaalpaadpd 57 +A+ +l++g+ +eA++l+++l + d FUN_000574-T1 1031 SVMADYYLNNGHHEEARQLFERLVRTDFV 1059 468999*****************998866 PP == domain 4 score: 2.1 bits; conditional E-value: 0.54 TPR_19 17 alaedPdnaearllLArallalgrldeA 44 a+a++P++ ++ +LA ++ +++++A FUN_000574-T1 1155 AHAKFPEDTIILHNLAMCHAFYKDYEKA 1182 6899**********************98 PP == domain 5 score: 12.6 bits; conditional E-value: 0.00027 TPR_19 5 gdydeAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpd 57 +dy++A +++++l + P++ ++ +++r l +g++ +A++ L + ++ + d FUN_000574-T1 1177 KDYEKACVYFKELLRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTLKIAED 1229 79******************************************999988766 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 3.1 2.1e+03 42 62 .. 127 147 .. 124 155 .. 0.79 2 ! 32.2 0.0 2.3e-10 1.6e-07 18 160 .. 275 412 .. 264 414 .. 0.72 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 3.1 NPHP3_N 42 vidhlqaegsavayfffdfsd 62 + hl++ g+++a+fff++++ FUN_000574-T1 127 LHGHLRDPGKRAACFFFRDKS 147 55699999********98876 PP == domain 2 score: 32.2 bits; conditional E-value: 2.3e-10 NPHP3_N 18 spsdssllwlsGkpGsGKsvlastvidhlqae.gsavayfffdfsdeekqslssllrsllhqlasqlpelreelleklaedlgldekdlrelwekl 112 ++++++ l ++G +G+GK+ l + q++ ++++++ f ++++ + ++l+ ll + +++ ++ +++ e+ + ++++ r+l+++l FUN_000574-T1 275 GKKNPKHLVITGVAGAGKTCLLGNWSLQHQEKfPRDAVVCHFAGCTSASTVPGKILKRLLEEF----NNFLKS--KTAVEKETATSQEVRDLIQDL 364 3456789***************99987666653566666666666666666666666666665....444443..233344556778999****** PP NPHP3_N 113 letlllakslsrpvyiviDALDEceeseellellaellsksksklkvl 160 +tl + ++ + +iviDAL ++es + ++l l + +++ +++ FUN_000574-T1 365 TDTLTKISEAGYRAVIVIDALNKVDESGQTTKTLFWLPKMLPPNTHLI 412 *****9999999************999777776665555555666655 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.035 24 11 30 .. 827 846 .. 821 849 .. 0.81 2 ? 3.9 0.0 0.21 1.4e+02 6 31 .. 864 889 .. 861 891 .. 0.90 3 ? 1.1 0.0 1.7 1.1e+03 3 16 .. 904 917 .. 903 922 .. 0.85 4 ? 7.3 0.0 0.018 12 6 28 .. 1033 1055 .. 1033 1057 .. 0.89 5 ? 7.5 0.1 0.016 11 5 32 .. 1168 1195 .. 1166 1196 .. 0.86 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.035 TPR_6 11 lelgdkdeAkaalqrlikkY 30 ++ +++deA+++++r+++ + FUN_000574-T1 827 YKTNKFDEALEYYNRCLELH 846 5567*************987 PP == domain 2 score: 3.9 bits; conditional E-value: 0.21 TPR_6 6 lalsylelgdkdeAkaalqrlikkYP 31 ++ y +g++ e +++l++ ++ Y FUN_000574-T1 864 IGATYSSMGKWRECADVLEEALQLYE 889 7889999***************9996 PP == domain 3 score: 1.1 bits; conditional E-value: 1.7 TPR_6 3 llklalsylelgdk 16 ll+la++y +l+d+ FUN_000574-T1 904 LLNLAMAYVRLDDT 917 89********9654 PP == domain 4 score: 7.3 bits; conditional E-value: 0.018 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 +a+ yl+ g ++eA+++++rl++ FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVR 1055 577899999************96 PP == domain 5 score: 7.5 bits; conditional E-value: 0.016 TPR_6 5 klalsyle.lgdkdeAkaalqrlikkYPd 32 +la+++ d+++A+ ++++l++ P+ FUN_000574-T1 1168 NLAMCHAFyK-DYEKACVYFKELLRLQPE 1195 6899999856.*************98886 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.1 0.0 6.2e-10 4.2e-07 18 157 .. 273 401 .. 263 413 .. 0.70 Alignments for each domain: == domain 1 score: 31.1 bits; conditional E-value: 6.2e-10 AAA_16 18 rvrsgrpplvlvsGeaGvGKSalvrellraleraalvlsgkcdelqrglpyaallealtresllrqllaeseaallaawraalleela.avpaleg 112 ++ p ++++G aG+GK+ l+ + + +++ ++ +++ + +++ + ++ ++ ++l + ll+++ +l++ +a + ++++ FUN_000574-T1 273 QAGKKNPKHLVITGVAGAGKTCLLGNWSLQHQEK---FPRDAVVC-------HFAGCTSASTVPGKILKR----LLEEFNNFLKSKTAvEKETATS 354 556667899*******************999999...77777777.......455555555555555555....4444555555555522334455 PP AAA_16 113 eeaerllealsrllalaarkerplvlvlDdlqwadeasldl..laaL 157 +e ++l++ l++ l + ++++ v+v+D l de+++++ l L FUN_000574-T1 355 QEVRDLIQDLTDTLTKISEAGYRAVIVIDALNKVDESGQTTktLFWL 401 55699999999999777776777*************88776334444 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 0.0 5.9e-10 4e-07 3 162 .. 282 451 .. 280 455 .. 0.75 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 5.9e-10 NACHT 3 vilqGeaGsGKTtLlqklalawaegklpqdafklvFflslrelsrsgkalsladll..fsqlpepaapvse.................viavllel 79 ++++G aG GKT Ll l+ ++k p+da+ F + ++ + +gk+ l++ll f+++++++ +v++ + + e FUN_000574-T1 282 LVITGVAGAGKTCLLGNWSLQH-QEKFPRDAVVCHFAGCTSASTVPGKI--LKRLLeeFNNFLKSKTAVEKetatsqevrdliqdltdTLTKISEA 374 689*************987765.55668877666666666666666666..555554445556666665555666677555555555445555555 PP NACHT 80 perlLlilDGlDelksqlgqpkekqpvrtlLssllrkkllpeasllltvrpdalrklregleea..avlevegfseedrkeyvrk 162 r+++++D+l+++++ + ++tl+ +l+k l+p+++l+++v + + k++e+ ee+ av+ + +++ ++r+e++ FUN_000574-T1 375 GYRAVIVIDALNKVDESGQT------TKTLF--WLPKMLPPNTHLIVSVAESDVVKVAELTEERdyAVISLSPLKGPEREEIALA 451 55555**********96666......89999..*******************************999999******999998765 PP >> NPHP3_hel Nephrocystin 3, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.1 1.3e-09 8.5e-07 24 134 .. 464 573 .. 448 597 .. 0.76 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 1.3e-09 NPHP3_hel 24 kklerhcrsaatcnalyvtllakliaeaktaekldevleqclqcqdtvsly.rlvlrsvqetlsterekelmkeilclvsvshnGvsesellelfp 118 +k+ + a t n+l++ +l ++++++ +ld l+ lq + t l+ ++ r q+ +e + +l+k+i+c + v+ G+se+el ++ FUN_000574-T1 464 QKI-KIVSKAQTENPLFLKILLEELCSFGEFFQLDGYLDGLLQANSTKELFlKFLERLEQDYNPEEYDGNLIKDIMCCILVARQGLSETELKAIL- 557 333.345678999************************************99355556778899999************************97764. PP NPHP3_hel 119 dltwpvltsllhklqk 134 +++ ++ + + + +++ FUN_000574-T1 558 NISDQMWSVVFFAIEE 573 3444444444444444 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.0 6.6e-09 4.4e-06 4 96 .. 278 388 .. 275 413 .. 0.76 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 6.6e-09 AAA_22 4 tagilvltGesGtGKTtllrrlleqldee..ddsvv..lvelpsst.spkdllrellralglelek..........elskeellaalqealkalaa 84 + ++lv+tG +G+GKT ll + q++e+ +d vv + ++s + p ++l++ll+++++ l++ +e+++++q++ ++l + FUN_000574-T1 278 NPKHLVITGVAGAGKTCLLGNWSLQHQEKfpRDAVVchFAGCTSAStVPGKILKRLLEEFNNFLKSktaveketatS---QEVRDLIQDLTDTLTK 370 6789*********************9988*86666688888888887899999999999999999999*****6663...4444444444444444 PP AAA_22 85 ......ravliiDEaqnl 96 rav++iD ++ FUN_000574-T1 371 iseagyRAVIVIDALNKV 388 4447777******76665 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 6.1 4.1e+03 15 34 .] 818 837 .. 816 837 .. 0.89 2 ? 3.5 0.0 0.22 1.5e+02 13 31 .. 858 876 .. 838 878 .. 0.85 3 ? -1.4 0.0 8.7 5.8e+03 15 28 .. 903 916 .. 898 919 .. 0.80 4 ? 5.7 0.0 0.045 30 19 34 .] 1033 1048 .. 1027 1048 .. 0.92 5 ? 4.9 0.0 0.082 55 8 33 .. 1158 1183 .. 1157 1184 .. 0.91 6 ? 4.0 0.0 0.16 1.1e+02 1 33 [. 1185 1217 .. 1185 1218 .. 0.92 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 6.1 TPR_17 15 ayynLArlllnnGqleeAlq 34 +++ L++l + ++++eAl+ FUN_000574-T1 818 SLNGLGVLCYKTNKFDEALE 837 7899*************985 PP == domain 2 score: 3.5 bits; conditional E-value: 0.22 TPR_17 13 adayynLArlllnnGqlee 31 +d ++n + +++ +G++ e FUN_000574-T1 858 PDTLNNIGATYSSMGKWRE 876 799************9876 PP == domain 3 score: -1.4 bits; conditional E-value: 8.7 TPR_17 15 ayynLArlllnnGq 28 + nLA+++ ++++ FUN_000574-T1 903 TLLNLAMAYVRLDD 916 689******98877 PP == domain 4 score: 5.7 bits; conditional E-value: 0.045 TPR_17 19 LArlllnnGqleeAlq 34 +A ++lnnG++eeA+q FUN_000574-T1 1033 MADYYLNNGHHEEARQ 1048 799***********98 PP == domain 5 score: 4.9 bits; conditional E-value: 0.082 TPR_17 8 ldPnnadayynLArlllnnGqleeAl 33 + P + +++nLA+++ +++e+A+ FUN_000574-T1 1158 KFPEDTIILHNLAMCHAFYKDYEKAC 1183 5699999****************995 PP == domain 6 score: 4.0 bits; conditional E-value: 0.16 TPR_17 1 lylkaleldPnnadayynLArlllnnGqleeAl 33 ++++ l+l+P ++ + +n++r l G+ +A+ FUN_000574-T1 1185 YFKELLRLQPEDVAIGTNYGRMLALSGEVYKAI 1217 6899***********************998887 PP >> NPHP3 Nephrocystin-3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 5.2e-05 0.035 6 75 .. 12 88 .. 9 91 .. 0.74 2 ? 3.1 0.0 0.17 1.1e+02 81 110 .. 122 151 .. 113 170 .. 0.77 3 ? 1.7 0.0 0.48 3.2e+02 112 155 .. 179 221 .. 167 225 .. 0.78 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 5.2e-05 NPHP3 6 vRvYliate.dtqaevdiflkeyspkLqrlCetlGrfflvvhfpeekaaqyl......aerkreiekssivvlllks 75 Rv+++++ +e + ++k+y p+L +lC G+ f+ v + +++++ + re+++s ++v++ ++ FUN_000574-T1 12 ARVFFSSPFgGLEEEREELTKKYWPQLSSLCKKAGYEFVPVDMRWGITSEMSskaatiEICLREMDRSDMIVGFFGQ 88 577777664145778899***********************997664444432222225577999999999999875 PP == domain 2 score: 3.1 bits; conditional E-value: 0.17 NPHP3 81 lledveeaflknpeakplllylrteegkss 110 + ++ +++l++p+++++ + +r+++ + FUN_000574-T1 122 TELEFLHGHLRDPGKRAACFFFRDKSYDDL 151 5668889****************8876554 PP == domain 3 score: 1.7 bits; conditional E-value: 0.48 NPHP3 112 esvqqllekvkkvdkankakiidhsgspeegaeevyselekiik 155 e +l +v+++ + ++ + ++++p+ ga+ +y +ek ++ FUN_000574-T1 179 EYLADLKARVEAT-HDQCLAVHMNYKNPQVGAKLMYETIEKYLR 221 4556667777765.5789999999*****************876 PP >> RNPP_C RNPP family C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 0.00014 0.094 80 150 .. 772 845 .. 725 850 .. 0.82 2 ? 0.6 0.0 0.72 4.8e+02 78 118 .. 1025 1066 .. 989 1069 .. 0.86 3 ? 6.2 0.5 0.013 9 78 163 .. 1162 1239 .. 1130 1249 .. 0.85 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.00014 RNPP_C 80 hiknslAnvyAeegkinksielyqqvldeseaqeedyeelkikvl...YnysklLydkndydsslevinqaikl 150 ++ nslA +y + +++ k+ l+++vl+ e++ +++++ + v + l y++n++d++le+ n+ ++l FUN_000574-T1 772 QMTNSLACMYVDVEEFAKAEPLHKEVLEVREKFADKWKDGWSSVAtslNGLGVLCYKTNKFDEALEYYNRCLEL 845 579*******************************999988877751114468899***************9875 PP == domain 2 score: 0.6 bits; conditional E-value: 0.72 RNPP_C 78 elhiknsl.AnvyAeegkinksielyqqvldeseaqeedyee 118 + i+ns+ A y ++g+ +++ +l+++++ + ++d+ FUN_000574-T1 1025 SIPILNSVmADYYLNNGHHEEARQLFERLVRTDFVSDRDFAA 1066 6789999538899999999********999888888888766 PP == domain 3 score: 6.2 bits; conditional E-value: 0.013 RNPP_C 78 elhiknslAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiekenmsLLGql 163 + i+ lA+ +A +k+ +++++l q ed + + ny+++L ++ +++e+ +++k++ +k++ +L+ q+ FUN_000574-T1 1162 DTIILHNLAMCHAFYKDYEKACVYFKELL---RLQPED-----VAIGTNYGRMLALSGEVYKAIEQLTRTLKIAEDKNEETLIEQI 1239 66789999*************99******...333333.....3567899************************999999999887 PP >> ATPase_2 ATPase domain predominantly from Archaea # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 1e-06 0.0007 11 157 .. 270 420 .. 268 445 .. 0.79 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 1e-06 ATPase_2 11 leelaergtneiiviYGpegcGKtallkeiienleelgkeviYvsaleeeseskldefeekkklaealaeavpkaeleev.......sklvelaie 99 +++ a +++ + +vi+G g GKt ll + +++e+ + v + + ++++ + k+l e +++ ++++++ e +++ ++++ FUN_000574-T1 270 VKSQAGKKNPKHLVITGVAGAGKTCLLGNWSLQHQEKFPRDAVVCHFAGCTSASTVPGKILKRLLEEFNNFLKSKTAVEKetatsqeVRDLIQDLT 365 5666778888999**************99888887766677777888888888887777888888888666666666555566666889999999* PP ATPase_2 100 llleaikkkgkkiiiiiDevqkliglnkaellvkeLlnlieyltkekelivvivasSe 157 ++l +i++ g + +i+iD + k+ ++++ k L+ l + l+ +++liv ++ s FUN_000574-T1 366 DTLTKISEAGYRAVIVIDALNKVD---ESGQTTKTLFWLPKMLPPNTHLIVSVAESDV 420 ******************999877...6778888888888889999999988877764 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.61 4.1e+02 9 60 .. 830 889 .. 822 892 .. 0.57 2 ? -1.2 0.0 4.4 3e+03 17 44 .. 880 916 .. 864 921 .. 0.50 3 ! 14.2 0.0 7.2e-05 0.048 8 64 .. 1176 1232 .. 1169 1241 .. 0.89 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.61 TPR_9 9 edleralavverllll........aPddpeerrdrGllyaqlgcleaAladLeaylalap 60 +++++al++++r l l ++ p+ + + G y +g + + ++ Le +l+l + FUN_000574-T1 830 NKFDEALEYYNRCLELhrrslpptHHLIPDTLNNIGATYSSMGKWRECADVLEEALQLYE 889 556667777777666655554322222245555566666666666666666666666655 PP == domain 2 score: -1.2 bits; conditional E-value: 4.4 TPR_9 17 vverllll.........aPddpeerrdrGllyaqlgc 44 v+e l+l +Pd + + + +++y++l++ FUN_000574-T1 880 VLEEALQLyedayfgqlPPDVGGTLLNLAMAYVRLDD 916 3333333333333333366666666666666666665 PP == domain 3 score: 14.2 bits; conditional E-value: 7.2e-05 TPR_9 8 eedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeaylalapdapd 64 +d+e+a + ll+l+P+d+ ++G+++a +g + +A++ L + l++a+d FUN_000574-T1 1176 YKDYEKACVYFKELLRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTLKIAEDKNE 1232 589**********************************************99987654 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.15 1e+02 10 27 .. 826 843 .. 818 846 .. 0.86 2 ? 2.3 0.0 0.52 3.5e+02 10 25 .. 868 883 .. 860 887 .. 0.87 3 ! 8.9 0.0 0.004 2.7 5 28 .. 1032 1055 .. 1031 1058 .. 0.88 4 ? 0.1 0.1 2.6 1.7e+03 10 28 .. 1173 1191 .. 1168 1193 .. 0.80 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.15 PPR 10 ycknGkleeAlelfkeMk 27 + k +k++eAle++++ + FUN_000574-T1 826 CYKTNKFDEALEYYNRCL 843 7899**********9865 PP == domain 2 score: 2.3 bits; conditional E-value: 0.52 PPR 10 ycknGkleeAlelfke 25 y++ Gk++e+ ++++e FUN_000574-T1 868 YSSMGKWRECADVLEE 883 999***********98 PP == domain 3 score: 8.9 bits; conditional E-value: 0.004 PPR 5 slIsgycknGkleeAlelfkeMke 28 ++ + y nG +eeA +lf+++++ FUN_000574-T1 1032 VMADYYLNNGHHEEARQLFERLVR 1055 6778899*************9876 PP == domain 4 score: 0.1 bits; conditional E-value: 2.6 PPR 10 ycknGkleeAlelfkeMke 28 ++ ++e+A +fke+++ FUN_000574-T1 1173 HAFYKDYEKACVYFKELLR 1191 5556799*********987 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 5.5 3.7e+03 67 110 .. 882 926 .. 877 935 .. 0.80 2 ? 6.7 0.1 0.013 8.6 75 146 .. 935 1011 .. 926 1014 .. 0.80 3 ! 7.4 0.0 0.0078 5.2 63 106 .. 1176 1216 .. 1131 1239 .. 0.74 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 5.5 TPR_CcmH_CycH 67 etAiqAfekAl..klapnnteiklsYaqaLmlsgdeedlkkAeelL 110 e+A+q +e A+ +l p+ + l++a a ++ +d ++ +Ae+l+ FUN_000574-T1 882 EEALQLYEDAYfgQLPPDVGGTLLNLAMAYVRLDDTGSN-RAESLY 926 7889999999888899**************999999865.555554 PP == domain 2 score: 6.7 bits; conditional E-value: 0.013 TPR_CcmH_CycH 75 kAlklapnnt.eiklsYaqaLml...sgdeedlkkAeelLkkllkqdptn.lralsllAfnafeqgdyeeAiaaWqk 146 kA+ + +++ ++ lsY+ L++ + ++e k+A+++ +k ++tn l+al +A+ + ++++eA +++k FUN_000574-T1 935 KAYGRDHSDVgQTLLSYSAFLLRvdpKRSAEVAKQAADIFEKSFGLEHTNtLNALENVALAFATSKEFAEAHPYFKK 1011 666666555427899******99333345667789999*******99999569*******************99986 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0078 TPR_CcmH_CycH 63 lndaetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlkkA 106 +d+e+A f+ l+l+p++++i ++Y ++L lsg+ kA FUN_000574-T1 1176 YKDYEKACVYFKELLRLQPEDVAIGTNYGRMLALSGEVY---KA 1216 567777777888888888888888888888888888765...34 PP >> DAP3 Mitochondrial ribosomal death-associated protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.013 8.8 14 40 .. 270 296 .. 263 315 .. 0.88 2 ! 8.6 0.0 0.002 1.4 235 288 .. 967 1019 .. 927 1041 .. 0.86 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.013 DAP3 14 lkkaekkkkvkrlvltGekgsGKSvlL 40 +k+++ kk+ k lv+tG g GK+ lL FUN_000574-T1 270 VKSQAGKKNPKHLVITGVAGAGKTCLL 296 6777899999**************998 PP == domain 2 score: 8.6 bits; conditional E-value: 0.002 DAP3 235 arpqldpYvkkydkrvaealkgkvevieveglskeEarslleyyaesgvlrekv 288 a++++d + k++ +++ + l+ +e + + +++E+++ y+++sgv+r+++ FUN_000574-T1 967 AKQAADIFEKSFGLEHTNTLN-ALENVALAFATSKEFAEAHPYFKKSGVVRHRK 1019 2267799**99**********.*****************************973 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.1 0.002 1.3 82 162 .. 758 849 .. 741 855 .. 0.79 2 ? 5.3 0.0 0.034 23 50 124 .. 981 1056 .. 935 1068 .. 0.74 3 ? -1.1 0.0 3.1 2.1e+03 25 86 .. 1167 1228 .. 1153 1244 .. 0.70 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.002 ARM_TT21_C 82 skleysveeadelekawLlladiyiqsgkldlAeeLlkkvlkynk...........scakAyellGliaekeqsykdAaenYekAWklskes 162 ++++y+++ a+ +++ la +y++ +++ +Ae L k vl+ + s a + lG+++ k +++ +A e+Y++ +l+ +s FUN_000574-T1 758 EEIKYHPKIAETFCQMTNSLACMYVDVEEFAKAEPLHKEVLEVREkfadkwkdgwsSVATSLNGLGVLCYKTNKFDEALEYYNRCLELHRRS 849 5689999**********************************9764122222223325555667899*****************998887665 PP == domain 2 score: 5.3 bits; conditional E-value: 0.034 ARM_TT21_C 50 aekdsvpallalaealvllkqtqkArnqLkriskleysveead.elekawLlladiyiqsgkldlAeeLlkkvlky 124 +++++ al +a a+++ k+ ++A k+ + ++ +++ + ++ad y+++g++++A++L ++ ++ FUN_000574-T1 981 EHTNTLNALENVALAFATSKEFAEAHPYFKKSGVVRHRKGQMNsSIPILNSVMADYYLNNGHHEEARQLFERLVRT 1056 346778888999999************99997777777776663555556689*****************998765 PP == domain 3 score: -1.1 bits; conditional E-value: 3.1 ARM_TT21_C 25 allllaskekteiekalkeltelleaekdsvpallalaealvllkqtqkArnqLkriskley 86 + l++++ ++ eka ++ell+ ++++v++ + + l+l + kA +qL r k+ FUN_000574-T1 1167 HNLAMCHAFYKDYEKACVYFKELLRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTLKIAE 1228 44455555666777777888888888888888777777777778888888888877766655 PP >> Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.2 0.0063 4.2 9 31 .. 824 846 .. 822 849 .. 0.88 2 ? 6.6 0.1 0.019 13 4 33 .. 1166 1195 .. 1164 1197 .. 0.90 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0063 Fis1_TPR_C 9 vGhyklgeYseArryvdalLeie 31 v +yk + ++eA++y +++Le + FUN_000574-T1 824 VLCYKTNKFDEALEYYNRCLELH 846 559*****************976 PP == domain 2 score: 6.6 bits; conditional E-value: 0.019 Fis1_TPR_C 4 lYylAvGhyklgeYseArryvdalLeiePe 33 l+ lA h+ ++Y++A y + lL+ +Pe FUN_000574-T1 1166 LHNLAMCHAFYKDYEKACVYFKELLRLQPE 1195 56689999999*****************98 PP >> TPR_20 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.1 0.34 2.3e+02 28 60 .. 1033 1065 .. 1029 1079 .. 0.85 2 ? 8.9 0.0 0.004 2.7 15 71 .. 1190 1246 .. 1185 1251 .. 0.87 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.34 TPR_20 28 lAlallaagrneeAleqLleilkrdrnaeddaa 60 +A+ +l++g++eeA +++ +++++d ++d a FUN_000574-T1 1033 MADYYLNNGHHEEARQLFERLVRTDFVSDRDFA 1065 6999**********9999999999987777755 PP == domain 2 score: 8.9 bits; conditional E-value: 0.004 TPR_20 15 laadpddlearldlAlallaagrneeAleqLleilkrdrnaeddaarkqlleifeal 71 l +p+d+++ +++ l+ +g++ +A+eqL + lk + +++ +q+ ++++l FUN_000574-T1 1190 LRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTLKIAEDKNEETLIEQINSYLKLL 1246 5668************************************99998877777777665 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.016 10 33 82 .] 826 884 .. 815 884 .. 0.77 2 ? 0.9 0.0 1.2 8.4e+02 30 48 .. 1034 1052 .. 1024 1058 .. 0.82 3 ? 3.0 0.1 0.27 1.8e+02 3 50 .. 1177 1225 .. 1155 1236 .. 0.81 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.016 ANAPC3 33 lflngqykrAyellrka.klneksl........gcryllAqcllkLkkykeAldaLeka 82 ++++++++A+e+ +++ +l +sl + + + ++ ++k++e+ d+Le+a FUN_000574-T1 826 CYKTNKFDEALEYYNRClELHRRSLppthhlipDTLNNIGATYSSMGKWRECADVLEEA 884 57778877777777777777777777655567888888899999999999999999985 PP == domain 2 score: 0.9 bits; conditional E-value: 1.2 ANAPC3 30 AqclflngqykrAyellrk 48 A ++++ng +++A +l+++ FUN_000574-T1 1034 ADYYLNNGHHEEARQLFER 1052 7888999999999888776 PP == domain 3 score: 3.0 bits; conditional E-value: 0.27 ANAPC3 3 hqyknAiflaerllaaepespedayllAqclflngqykrAyellrka.k 50 ++y+ A+ ++ ll +pe+ ++ l l+g+ ++A+e l + k FUN_000574-T1 1177 KDYEKACVYFKELLRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTlK 1225 5788888888888866666666666689999999999999999998755 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.83 5.6e+02 3 17 .. 903 917 .. 901 918 .. 0.87 2 ? 8.3 0.0 0.009 6 6 26 .] 1032 1052 .. 1031 1052 .. 0.91 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.83 TPR_4 3 allaLArallalGdl 17 +ll+LA+a+ +l d FUN_000574-T1 903 TLLNLAMAYVRLDDT 917 689********9985 PP == domain 2 score: 8.3 bits; conditional E-value: 0.009 TPR_4 6 aLArallalGdldeAraller 26 ++A +l G+++eAr+l+er FUN_000574-T1 1032 VMADYYLNNGHHEEARQLFER 1052 67999**************97 PP >> PPR_2 PPR repeat family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.7 1.8e+03 13 27 .. 826 840 .. 824 854 .. 0.85 2 ? -0.9 0.0 3.9 2.6e+03 19 37 .. 881 899 .. 876 900 .. 0.84 3 ? 8.4 0.0 0.0049 3.3 11 32 .. 1035 1056 .. 1028 1062 .. 0.84 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.7 PPR_2 13 yckkgkveeAfklfn 27 + k +k++eA++ +n FUN_000574-T1 826 CYKTNKFDEALEYYN 840 6799********998 PP == domain 2 score: -0.9 bits; conditional E-value: 3.9 PPR_2 19 veeAfklfneMkkrgvkPd 37 +eeA++l+++ ++Pd FUN_000574-T1 881 LEEALQLYEDAYFGQLPPD 899 79*******9888888887 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0049 PPR_2 11 ngyckkgkveeAfklfneMkkr 32 ++y+++g++eeA +lf+ ++ FUN_000574-T1 1035 DYYLNNGHHEEARQLFERLVRT 1056 79**************988775 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.0017 1.2 124 194 .. 818 891 .. 758 900 .. 0.82 2 ? -0.0 0.0 0.87 5.8e+02 175 228 .. 1000 1053 .. 906 1066 .. 0.63 3 ? -1.2 0.0 1.9 1.3e+03 292 313 .. 1209 1230 .. 1202 1239 .. 0.83 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0017 TPR_MalT 124 llvgladLlyEwndLeeAeqhlqqgiqlgrql.ep.aaaleayvllarval.aqGeleeAetllqraerlares 194 l gl+ L y n+++eA ++ + ++l r+ p ++ ++ ++ + ++ + G+++e +l++a +l++ + FUN_000574-T1 818 SLNGLGVLCYKTNKFDEALEYYNRCLELHRRSlPPtHHLIPDTLNNIGATYsSMGKWRECADVLEEALQLYEDA 891 56788999999999999999999999999996444699999999999887725799999999999999998865 PP == domain 2 score: -0.0 bits; conditional E-value: 0.87 TPR_MalT 175 GeleeAetllqraerlaresrfhvdwlanaeavrvrlwlargdlraaeewlraa 228 e eA+ ++++ + +++ + + + ++v ++l g+ + a+++ + FUN_000574-T1 1000 KEFAEAHPYFKKSGVVRHRKGQMNSSIPILNSVMADYYLNNGHHEEARQLFERL 1053 444445555544444444444444444444455555555555555555444443 PP == domain 3 score: -1.2 bits; conditional E-value: 1.9 TPR_MalT 292 algqeeeAlaaLlqaLeLAepe 313 g+ +A+++L++ L++Ae++ FUN_000574-T1 1209 LSGEVYKAIEQLTRTLKIAEDK 1230 4678889999999999999975 PP >> KAP_NTPase KAP family P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.3 0.00033 0.22 124 195 .. 342 424 .. 270 433 .. 0.75 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00033 KAP_NTPase 124 a........kslqkeveellkdiestlkd...lnkrivviiDdLDRceqeeirelleavrllfsf..knvkfiLaaDeeiikkal 195 + ++ev l++d+ +tl++ + r v++iD L ++ +e ++ ++++ l ++ +n+ +i+++ e+ + k FUN_000574-T1 342 KsktavekeTATSQEVRDLIQDLTDTLTKiseAGYRAVIVIDALNKV--DESGQTTKTLFWLPKMlpPNTHLIVSVAESDVVKVA 424 033334444889999**************998999**********95..677788888888888887888888888777776655 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.00094 0.63 14 38 .] 829 853 .. 820 853 .. 0.87 2 ? -2.5 0.1 8.1 5.4e+03 24 32 .. 881 889 .. 881 892 .. 0.85 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00094 SHNi-TPR 14 nenFeqAvkDlrkaLeLreellppe 38 + +F++A++ + ++LeL + lpp+ FUN_000574-T1 829 TNKFDEALEYYNRCLELHRRSLPPT 853 679*****************99986 PP == domain 2 score: -2.5 bits; conditional E-value: 8.1 SHNi-TPR 24 lrkaLeLre 32 l++aL+L+e FUN_000574-T1 881 LEEALQLYE 889 799****98 PP >> HAT_Syf1_M Pre-mRNA-splicing factor SYF1 middle HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 2.3 1.6e+03 80 107 .. 771 798 .. 764 803 .. 0.83 2 ? 10.0 0.0 0.0012 0.83 78 117 .. 1025 1065 .. 961 1069 .. 0.82 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 2.3 HAT_Syf1_M 80 GklwtsLadyyirlgefekaRdvfeegi 107 ++ +sLa y+ ++ef ka +++e + FUN_000574-T1 771 CQMTNSLACMYVDVEEFAKAEPLHKEVL 798 577899**************99988866 PP == domain 2 score: 10.0 bits; conditional E-value: 0.0012 HAT_Syf1_M 78 qaGklwtsLadyyirlgefekaRdvfeegitt.vmtvrdFt 117 l + +adyy+++g+ e aR++fe ++t + rdF+ FUN_000574-T1 1025 SIPILNSVMADYYLNNGHHEEARQLFERLVRTdFVSDRDFA 1065 555677889******************99876356678886 PP >> ARM_TT21_5th TT21 fifth ARM repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 3.1 2.1e+03 44 89 .. 730 775 .. 721 780 .. 0.83 2 ? -1.7 0.0 7.3 4.9e+03 79 98 .. 823 842 .. 812 857 .. 0.75 3 ? -1.0 0.0 4.3 2.9e+03 6 28 .. 1032 1054 .. 982 1067 .. 0.70 4 ? 8.0 0.1 0.0074 5 15 70 .. 1177 1232 .. 1161 1252 .. 0.73 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.1 ARM_TT21_5th 44 llrrsGkleeaekflekaekassraklepgfnyckglyewytgkln 89 + +G+++ +e fl++a k ++ a+ e + +y + e++++ +n FUN_000574-T1 730 FQGDAGNMTAMEPFLNRAIKLLKFAHSEEEIKYHPKIAETFCQMTN 775 556789**************99999999999998888887776555 PP == domain 2 score: -1.7 bits; conditional E-value: 7.3 ARM_TT21_5th 79 glyewytgklneaLrefnka 98 g+++ t+k eaL+++n++ FUN_000574-T1 823 GVLCYKTNKFDEALEYYNRC 842 55666667777777777765 PP == domain 3 score: -1.0 bits; conditional E-value: 4.3 ARM_TT21_5th 6 mmAdlafrkqdlekAifhfqqlL 28 +mAd + ++e+A + f+ l+ FUN_000574-T1 1032 VMADYYLNNGHHEEARQLFERLV 1054 46666666666666666666665 PP == domain 4 score: 8.0 bits; conditional E-value: 0.0074 ARM_TT21_5th 15 qdlekAifhfqqlLekkpdnyeaLarliellrrsGkleeaekflekaekassrakl 70 +d+ekA ++f++lL+ +p++ ++ ++ ++l sG++ +a + l++ k ++++++ FUN_000574-T1 1177 KDYEKACVYFKELLRLQPEDVAIGTNYGRMLALSGEVYKAIEQLTRTLKIAEDKNE 1232 69********************9999999999999876665555544444333333 PP >> AIPR_N Abortive infection phage resistance protein N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 0.00051 0.34 50 123 .. 312 385 .. 308 396 .. 0.85 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00051 AIPR_N 50 fvsdfsgdeelqtltkteiekafkrllnFlekalegklakeleesseaydlaelieeakkeisk..vrlfllTdge 123 +v++f g ++ +t++ + +++++++ nFl+ + ++ke s+e+ dl++++ ++ ++is+ +r +++ d+ FUN_000574-T1 312 VVCHFAGCTSASTVPGKILKRLLEEFNNFLKSKTA--VEKETATSQEVRDLIQDLTDTLTKISEagYRAVIVIDAL 385 899***************************98855..799*******************99986445666666655 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.013 8.4 3 23 .. 825 845 .. 823 849 .. 0.89 2 ? -1.5 0.0 4.5 3e+03 28 42 .] 858 872 .. 858 872 .. 0.90 3 ? -1.0 0.1 3 2e+03 8 23 .. 872 887 .. 865 891 .. 0.55 4 ? 0.4 0.0 1.2 7.8e+02 9 30 .. 1178 1199 .. 1177 1211 .. 0.88 5 ? -1.5 0.0 4.5 3e+03 1 24 [. 1204 1227 .. 1204 1230 .. 0.82 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.013 TPR_11 3 ayyeqGkyeeAieaYkkAlkl 23 ++y+ +k++eA+e Y++ l+l FUN_000574-T1 825 LCYKTNKFDEALEYYNRCLEL 845 689*************98887 PP == domain 2 score: -1.5 bits; conditional E-value: 4.5 TPR_11 28 aeayynLGlayykqG 42 ++ ++n+G++y +G FUN_000574-T1 858 PDTLNNIGATYSSMG 872 7899*******9887 PP == domain 3 score: -1.0 bits; conditional E-value: 3 TPR_11 8 GkyeeAieaYkkAlkl 23 Gk+ e ++++Al+l FUN_000574-T1 872 GKWRECADVLEEALQL 887 5555555555566555 PP == domain 4 score: 0.4 bits; conditional E-value: 1.2 TPR_11 9 kyeeAieaYkkAlkldPdnaea 30 +ye+A +k+ l+l P+++ + FUN_000574-T1 1178 DYEKACVYFKELLRLQPEDVAI 1199 79999999*********99876 PP == domain 5 score: -1.5 bits; conditional E-value: 4.5 TPR_11 1 GdayyeqGkyeeAieaYkkAlkld 24 G+++ G+ +Aie++ + lk+ FUN_000574-T1 1204 GRMLALSGEVYKAIEQLTRTLKIA 1227 77888899999*****98888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1254 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1240 (0.0485418); expected 510.9 (0.02) Passed bias filter: 1030 (0.040321); expected 510.9 (0.02) Passed Vit filter: 124 (0.00485418); expected 25.5 (0.001) Passed Fwd filter: 39 (0.00152672); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 38 [number of targets reported over threshold] # CPU time: 0.58u 0.41s 00:00:00.99 Elapsed: 00:00:00.44 # Mc/sec: 11580.53 // Query: FUN_000575-T1 [L=262] Description: FUN_000575 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-41 141.6 12.8 4.9e-41 141.4 12.8 1.0 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.016 15.2 0.9 0.029 14.3 0.9 1.3 1 DUF3810 Protein of unknown function (DUF3810) 3 7.9 9.7 2.2 8.3 4.6 2.1 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 141.4 12.8 5.7e-45 4.9e-41 36 260 .] 2 219 .. 1 219 [. 0.94 Alignments for each domain: == domain 1 score: 141.4 bits; conditional E-value: 5.7e-45 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 36 lvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkrralvlilvvWvlalllslppllfsgtktesa 131 l++pf+++y+ ++w+fg vlCk++ a ++++++asi +l+aisi+RYlaI p + ++t ++a+ li+v+W+++ll++lp + +++ + + FUN_000575-T1 2 LCIPFTVLYYE-FEYWPFGFVLCKIIPATQTICIMASIGTLAAISIERYLAIAFPWEP--RVTASKARYLIAVIWLIGLLIGLPIVAVMQLTYV-- 92 799****9999.6*******************************************99..88*************************9988766.. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 132 ekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkkksarker.kalktllvvvvvfvlcwlPyfilllld 226 + C+ + ++ ++ +y +l++ l++ +pl +i+ +y+ i+ +l ++a++ ++++ ++ +k + k++++l++vvv+++lc+lPy+++ l+ FUN_000575-T1 93 -DGLPLCMEKGWP-SEIFRHVYSVLSFGLTYAIPLPMIAALYTVIVLKLNQAARETSDSEGFRIAKAKgKVIRMLIIVVVFYFLCYLPYHTTYLWL 186 .89****999776.4679****************************************99999988888*************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 227 sllkeceseklvetallitlllayvnsclNPiiY 260 + e + + + +l++++++ y+ns++NP++Y FUN_000575-T1 187 EF-GEGLQFRGIWLLLSYCHVMVYANSAVNPVLY 219 *9.66666777777889****************9 PP >> DUF3810 Protein of unknown function (DUF3810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.9 3.4e-06 0.029 10 85 .. 105 182 .. 102 190 .. 0.81 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 3.4e-06 DUF3810 10 skilsrlfgllpfSvgdllylllillllvylvkil..klkkkkkkkkkllkfllkillflsilyflFlllwglNYyrl 85 s+i+++++++l+f + + + l +i+ l ++v +l + +++++++ + + + + ++ ++i++++F++l+ l Y+ + FUN_000575-T1 105 SEIFRHVYSVLSFGLTYAIPLPMIAALYTVIVLKLnqAARETSDSEGFRIAKAKGKVIRMLIIVVVFYFLCYLPYHTT 182 899****************99999999888888886655555566666666777788888999999999999999865 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 4.6 0.00026 2.2 52 125 .. 5 79 .. 1 92 [. 0.76 2 ? 2.7 0.2 0.013 1.1e+02 121 148 .. 162 188 .. 113 217 .. 0.78 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00026 7TM_GPCR_Srx 52 Pmtllqsell...kellnshliglialglYeisplsqllialNRfcavffplkyekifsiknTkiiiviiwivslif 125 P t+l++e+ ++ ++i ++ ++ ++s+ + i+++R +a+ fp+ e+ + ++++++i++iw++ l++ FUN_000575-T1 5 PFTVLYYEFEywpFGFVLCKIIPATQTICIMASIGTLAAISIERYLAIAFPW--EPRVTASKARYLIAVIWLIGLLI 79 5555555554311122334477788999***********************9..78899999**********98875 PP == domain 2 score: 2.7 bits; conditional E-value: 0.013 7TM_GPCR_Srx 121 vslifitvlylpegCkllynpetltwsf 148 ++++ i+v+ ++ C+l y+ ++l ++f FUN_000575-T1 162 IRML-IIVVVFYFLCYLPYHTTYLWLEF 188 4455.44444456688888888776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (262 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 969 (0.0379331); expected 510.9 (0.02) Passed bias filter: 507 (0.0198473); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2660.46 // Query: FUN_000576-T1 [L=272] Description: FUN_000576 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-53 181.7 4.3 3.5e-53 181.2 4.3 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 8.4e-06 25.9 7.2 1.3e-05 25.3 7.2 1.2 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 1.9e-05 25.1 3.4 3.6e-05 24.2 3.4 1.4 1 7tm_4 Olfactory receptor Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 181.2 4.3 4.1e-57 3.5e-53 1 227 [. 44 265 .. 44 270 .. 0.93 Alignments for each domain: == domain 1 score: 181.2 bits; conditional E-value: 4.1e-57 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN lVi+v++++++l+t+t +++ nLavaDl v+ll++pf++vy+ l+ +w+fg ++Ck++ al+ ++++ s+ +++ais+DR+++Iv+p+ + + FUN_000576-T1 44 GNALVIFVVYKTRELHTVTGFLIANLAVADLGVGLLCIPFTVVYYELNFRWPFGPIMCKILPALMPCFVMGSVGTMLAISVDRHQSIVHPFGM--R 137 8*******************************************999**********************************************..7 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkk 192 +t+++ +++++++W+ all +lp l +++ ++ + +C+ ++p+ ++++y+l++++l++ +pl +++v+y++i +lr++ k ++++ FUN_000576-T1 138 VTRSQGKFVMVLIWLTALLPALPILGVMNFVRS---PNGESCQESWPT-GIPYPRIYLLCSFALTYAIPLPILIVIYIKIGMKLRQAIKDGADRRG 229 8**********************9987766555...9***********.345***********************************999998777 PP xx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 193 ks.arkerkalktllvvvvvfvlcwlPyfillllds 227 + a+++++++k+l +vv+ ++lc+lP++il +l FUN_000576-T1 230 FTqAQATKRIIKMLSAVVICYALCFLPFHILYFLID 265 65156677**********************999865 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 7.2 1.5e-09 1.3e-05 2 201 .. 39 255 .. 38 266 .. 0.80 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.5e-09 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladl....lclvgelvfvvllltgtqlkreeCFlliivyvfgltaqsvllLvigiDlliavkfP 93 ++ ++GN l+i++++k+++L++ + Li +++adl lc+ +++v l++ ++ C +l +++ +++ + +L+i +D+ + P FUN_000576-T1 39 LLATVGNALVIFVVYKTRELHTVTGFLIANLAVADLgvglLCIPFTVVYYELNF-RWPFGPIMCKILPALMPCFVMGSVGTMLAISVDRHQSIVHP 133 6789******************************96444488888888888999.89999************************************ PP 7TM_GPCR_Srsx 94 irYrllskek.YllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinviv.llvylvliiilkkkkek.......... 177 + r +++ ++++l+ + l ++ ++ + ++ + + C+ +i+ l s+++ ++ l + +v++i++ k + FUN_000576-T1 134 FGMRVTRSQGkFVMVLIWLTALLPALPILGVMNFVRSPNGESCQESWPTGIPYPRIYLLCSFALTYAIpLPILIVIYIKIGMKLRQaikdgadrrg 229 **9999888768887777766665544443333444446889999888888888999999998888773445555566544444445677999999 PP 7TM_GPCR_Srsx 178 ..kkssskkvlkslkvtvvififgWf 201 +++ +k+++k l+ +v+ + ++ + FUN_000576-T1 230 ftQAQATKRIIKMLSAVVICYALCFL 255 99*****************9988765 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 3.4 4.2e-09 3.6e-05 2 103 .. 35 137 .. 33 172 .. 0.81 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 4.2e-09 7tm_4 2 clvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfe.acllqlffihkfsllesavllamavdrfvai 96 +++l++ +Gn+ ++fv+ + lh +++a la++dlg+ + +P + + ++ r + c + ++ +f++ ++la++vdr+ +i FUN_000576-T1 35 VVIFLLATVGNALVIFVVYKTRELHTVTGFLIANLAVADLGVGLLCIPFTVVYYELNFRWPFGPiMCKILPALMPCFVMGSVGTMLAISVDRHQSI 130 57899999****************************************99888888877544331465555678999999999************* PP 7tm_4 97 ysplryt 103 ++p+ FUN_000576-T1 131 VHPFGMR 137 *997554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 736 (0.0288119); expected 510.9 (0.02) Passed bias filter: 334 (0.013075); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2649.51 // Query: FUN_000577-T1 [L=561] Description: FUN_000577 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.1e-21 74.9 0.0 1.5e-20 74.2 0.0 1.3 1 WS_DGAT_C WS/DGAT C-terminal domain ------ inclusion threshold ------ 0.049 14.4 3.3 0.47 11.2 0.7 2.4 2 YwiC YwiC-like protein 0.18 12.5 0.1 0.6 10.8 0.1 2.0 2 AnkUBD Ankyrin ubiquitin-binding domain Domain annotation for each model (and alignments): >> WS_DGAT_C WS/DGAT C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.2 0.0 1.8e-24 1.5e-20 3 142 .. 381 520 .. 379 522 .. 0.98 Alignments for each domain: == domain 1 score: 74.2 bits; conditional E-value: 1.8e-24 WS_DGAT_C 3 NqfglvllpLpvaladplerlrkakasmdrkKrslealltyallelllkllgakvaaalikrllsnttlviSNvpGPreelylaGapvkgiaplvp 98 Nqf+l +++Lpv+++ + rl+++++++++ le++++y +++l+l +++ +++++li++l++++ ++++ +pGP+ ++yl+G+ k +a ++p FUN_000577-T1 381 NQFSLAFINLPVGTEGAVPRLWETRRRVANFSFALESYIIYGFIKLCLLIFPLSAVRRLINFLINKAPCTVTQIPGPNTPVYLNGRMAKMMACWTP 476 ************************************************************************************************ PP WS_DGAT_C 99 glpgqalnitvlSyagklriglavdkdlipdpqkllddfeeale 142 + +l+i ++ g++++gl+ ++ +i +++ l+ +fe++ + FUN_000577-T1 477 RKTENGLSICLTHHGGQVHLGLVSHHSQINNCSLLIAEFEREVA 520 ***************************************99865 PP >> YwiC YwiC-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.7 5.5e-05 0.47 50 107 .. 37 98 .. 27 100 .. 0.85 2 ? 3.0 0.1 0.019 1.6e+02 56 94 .. 413 451 .. 399 454 .. 0.81 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 5.5e-05 YwiC 50 kq....rrkarylkwlliYgavalllllvvlllapallwlallalpllavnlyfakrrreRs 107 k+ ++ +l ++++ a+ + +l++++ +++++++l l +v +y+++rr++Rs FUN_000577-T1 37 KRlshpADRSNFLVRIVVFFAIWITHTLFFVFFVAVVILVVPLCYCLRGVMFYYSLRRNHRS 98 4454434788899999999******************************************7 PP == domain 2 score: 3.0 bits; conditional E-value: 0.019 YwiC 56 rylkwlliYgavalllllvvlllapallwlallalplla 94 +l++ +iYg++ l+ll++ l + +l+ +++ +p + FUN_000577-T1 413 FALESYIIYGFIKLCLLIFPLSAVRRLINFLINKAPCTV 451 4677899**************999999999887777665 PP >> AnkUBD Ankyrin ubiquitin-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.8 1.5e+04 13 21 .. 292 300 .. 277 303 .. 0.73 2 ? 10.8 0.1 7.1e-05 0.6 2 40 .. 319 357 .. 318 389 .. 0.85 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.8 AnkUBD 13 rmkktdwlf 21 m+ktd +f FUN_000577-T1 292 LMRKTDQIF 300 488888887 PP == domain 2 score: 10.8 bits; conditional E-value: 7.1e-05 AnkUBD 2 vdfkklkqiknrmkktdwlflnacvegvvesdlliveiy 40 vd+k +k+ik+ + ++l +cv g++ ++l +++ FUN_000577-T1 319 VDLKSVKRIKDVTRTKVDIILLSCVAGAIRAYLQKSKAI 357 9**********999777788889*********9988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (561 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 894 (0.0349971); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 5278.02 // Query: FUN_000578-T1 [L=961] Description: FUN_000578 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-57 193.4 21.0 8.9e-57 192.7 21.0 1.4 1 7tm_2 7 transmembrane receptor (Secretin family) 5.1e-14 53.0 7.0 5.1e-14 53.0 7.0 2.3 2 GPS GPCR proteolysis site, GPS, motif 0.00031 21.3 2.0 0.00031 21.3 2.0 2.0 2 CBM_14 Chitin binding Peritrophin-A domain 0.00057 20.2 0.0 0.0012 19.2 0.0 1.4 1 PA14 PA14 domain 0.00073 19.3 14.5 0.0013 18.4 14.0 1.5 1 Dicty_CAR Slime mold cyclic AMP receptor 0.0024 18.6 0.0 0.0073 17.1 0.0 1.8 1 GLEYA GLEYA domain Domain annotation for each model (and alignments): >> 7tm_2 7 transmembrane receptor (Secretin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 192.7 21.0 2.1e-60 8.9e-57 3 250 .] 559 793 .. 557 793 .. 0.98 Alignments for each domain: == domain 1 score: 192.7 bits; conditional E-value: 2.1e-60 7tm_2 3 slkvittvGlslSlvaLlvalailllfrklrctrnyihlnLflslilrallvlvkdealkneedqseaeaekvgCkvvavllhYfvlanfaWllvE 98 +l++it+vG++lSl+ l+++ i++ + lr++rn+ihlnL +++ + ++++l ++ea+ n kv Ckvvav lhYf+l+ faW+l+E FUN_000578-T1 559 ALEIITYVGCALSLAGVLLTVGIISCLSGLRSERNLIHLNLSVAIGIFQVIFLAGIEATTN----------KVICKVVAVWLHYFLLVWFAWMLIE 644 689**********************************************************..........************************* PP 7tm_2 99 glylytllvevffserkalkkylliGwGvPalvvaiwavvdakgylederCWlsneekllwiikgPvllvilvNfvlfinivrilvsklkesqkkk 194 g+yly+++++vf +++++l+ y + +G+P ++v i+a +gy++d+ CWls +++++++ +P+ll+il+N+v++ +++r +++ ++ ++ FUN_000578-T1 645 GIYLYLMVITVFDNNNEQLRLYGVCAYGIPGVIVLISASSAHEGYGTDSSCWLSVTNGVIYAFVVPALLIILMNTVILGLVIREIIRIQTNGVSNA 740 **************************************************************************************9999999999 PP 7tm_2 195 kdlkkalklvkstllllpLlgvtwvlglfavnpeevlsevflylelilnslqGlfv 250 ++ + +++ +ks +l pLlg+tw++g++a+ +++ vf+yl+++ nslqGlf+ FUN_000578-T1 741 TKFDLIKSGLKSITVLFPLLGITWIFGVLALGSQT---IVFQYLFALCNSLQGLFI 793 999999*****************************...****************98 PP >> GPS GPCR proteolysis site, GPS, motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.2 4.9 2.1e+04 20 34 .. 261 274 .. 261 275 .. 0.74 2 ! 53.0 7.0 1.2e-17 5.1e-14 1 45 [] 494 542 .. 494 542 .. 0.91 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 4.9 GPS 20 GCsltessnethtvC 34 GC+ + ++ ++++C FUN_000578-T1 261 GCQR-NGTSFDNVKC 274 8965.5559999999 PP == domain 2 score: 53.0 bits; conditional E-value: 1.2e-17 GPS 1 pqCvfWd...ssnsgtggWsteGC.sltessnethtvCsCnHltsFAvL 45 p+Cv+Wd +++++g Ws +GC t ssneth +C+CnHlt+FAvL FUN_000578-T1 494 PICVWWDfkaGDENSSGMWSRNGCtFDTFSSNETHSICKCNHLTNFAVL 542 89*******9667799********7457888*****************8 PP >> CBM_14 Chitin binding Peritrophin-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 2.0 7.4e-08 0.00031 1 43 [. 39 82 .. 39 91 .. 0.82 2 ? -4.6 1.4 6 2.6e+04 1 18 [. 262 278 .. 262 280 .. 0.69 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 7.4e-08 CBM_14 1 CegkedglyadpgdCskYyvCsngeaveftCpe.glvFdeetqk 43 C++k g y dp dC+kYy C+ g++ +t p+ gl+Fd ++++ FUN_000578-T1 39 CSDKRTGMYNDPMDCRKYYDCVGGITWHRTGPAvGLMFDSAKKA 82 **************************988887548999986653 PP == domain 2 score: -4.6 bits; conditional E-value: 6 CBM_14 1 CegkedglyadpgdC.skY 18 C+ +g+ +d+ +C +++ FUN_000578-T1 262 CQ--RNGTSFDNVKCaTQF 278 66..788888888886666 PP >> PA14 PA14 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 2.7e-07 0.0012 40 124 .. 136 227 .. 123 239 .. 0.77 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 2.7e-07 PA14 40 seaaddfsarwtGylkppesGtYtfkiasddgarlfvdg......elviDndgkqekksfada.speesktlelvaGkkYpirieYfeants 124 +++++++ r + ++++pesG Y f+++ l+ + +++i n +k ++k+ +d+ s ++sk + l +Gk+Y++++ + e+ + FUN_000578-T1 136 TQNRNHYGQRLRSFFRAPESGDYQFQTSCNYACQLWMSDdeqasrKRLIVNQKKIAGKFLFDRnSDQTSKNISLRKGKLYYMELLHKERISP 227 6677888889999***************99999***64422222244555555555555555516678899************999888766 PP >> Dicty_CAR Slime mold cyclic AMP receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 14.0 3.1e-07 0.0013 67 222 .. 614 770 .. 594 802 .. 0.80 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 3.1e-07 Dicty_CAR 67 eeaqesgfpcylyaivitygslacwlwtlclalsiynlivkrepepekfekyyfvlcwglplistivmlsk.evievvgnwcwigekyvgyrfglf 161 ea+++ c + a+ + y l + w l+ + +y++++ + ++ + y v +g+p +++++ s + + + cw++ + g + f FUN_000578-T1 614 IEATTNKVICKVVAVWLHYFLLVWFAWMLIEGIYLYLMVITVFDNNNEQLRLYGVCAYGIPGVIVLISASSaHEGYGTDSSCWLSVTN-GVIY-AF 707 567788999*************999****************999999999999999*****88777665541444557789***9864.4444.47 PP Dicty_CAR 162 ygpfliiwaisavlvgltsrytykvirnsvsdnkdkh.ltyqfklinyiivfl.vcwvfavvn 222 +p l+i + +v++gl r ++ n+vs+ + + +k i + +l + w+f v+ FUN_000578-T1 708 VVPALLIILMNTVILGLVIREIIRIQTNGVSNATKFDlIKSGLKSITVLFPLLgITWIFGVLA 770 89*****************************87654415667888888776655899999975 PP >> GLEYA GLEYA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.7e-06 0.0073 4 74 .. 145 219 .. 142 229 .. 0.75 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.7e-06 GLEYA 4 nhrGYfyapktgtYtfslsnaDdiallwlGdk..Aysg...wtranadleaty..sgssgsksvtvtltaGtyyPiRi 74 ++r +f ap++g+Y+f++ + + + lw+ d+ A + +++ ++ ++ +++s ++s +++l +G+ y + + FUN_000578-T1 145 RLRSFFRAPESGDYQFQT-SCNYACQLWMSDDeqASRKrliVNQK--KIAGKFlfDRNSDQTSKNISLRKGKLYYMEL 219 5899*************9.9*********9996555554333333..5555556666677777779999999996665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (961 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1408 (0.0551184); expected 510.9 (0.02) Passed bias filter: 621 (0.02431); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.47u 0.36s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 9146.32 // Query: FUN_000579-T1 [L=173] Description: FUN_000579 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-27 97.0 14.7 1.7e-27 96.6 14.7 1.2 1 Phospholip_A2_1 Phospholipase A2 0.0065 17.1 13.7 3.9 8.2 13.7 2.5 1 Phospholip_A2_2 Phospholipase A2 ------ inclusion threshold ------ 0.012 16.4 0.0 0.024 15.4 0.0 1.5 1 Phospholip_A2_4 Phospholipase A2-like domain Domain annotation for each model (and alignments): >> Phospholip_A2_1 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.6 14.7 2e-31 1.7e-27 1 109 [. 44 162 .. 44 163 .. 0.80 Alignments for each domain: == domain 1 score: 96.6 bits; conditional E-value: 2e-31 Phospholip_A2_1 1 llqlekmikcvtgkeallsyesYGcycglggkgtpvdatdrCClahdcCyeklkk..kgc.....kepklekykvs.vskkeitckse...... 80 l+q++ m+ c t++ ++++y +YGc+cg gg+g+pvd+tdrCCl+hd Cy+k+++ + c +++y+++ + c+ e FUN_000579-T1 44 LFQFGGMVACSTNR-SMFDYVDYGCWCGSGGSGKPVDQTDRCCLEHDLCYSKIRNdgSVCegwslFYIFFSSYSYTgC----RRCEPEykypvd 132 689***********.9*************************************9945556776554455555555322....222222444455 PP Phospholip_A2_1 81 .kkslcekqlCeCDkaaaeClakatynkky 109 k + c+k++CeCD +aa+C+ +a+ynk++ FUN_000579-T1 133 eKYKDCKKAICECDSQAAKCFGEAHYNKSH 162 58899**********************985 PP >> Phospholip_A2_2 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 13.7 0.00045 3.9 6 87 .. 67 159 .. 62 168 .. 0.56 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.00045 Phospholip_A2_2 6 kwCGagniaksykdlGaeketDkCCreHDhceekiealesk...ygltn..kslftishCe.c........dekfrkCLkk...vnssvselvg 82 wCG+g + k ++tD+CC eHD c +ki+ s ++l+ +s ++ + C+ c dek+++C k+ +s++++ g FUN_000579-T1 67 CWCGSGGSGKPV------DQTDRCCLEHDLCYSKIRNDGSVcegWSLFYifFSSYSYTGCRrCepeykypvDEKYKDCKKAiceCDSQAAKCFG 154 589998887765......579**************97644311133332113344444442231122222255666665552223444555566 PP Phospholip_A2_2 83 kiyfn 87 + ++n FUN_000579-T1 155 EAHYN 159 66665 PP >> Phospholip_A2_4 Phospholipase A2-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.0 2.8e-06 0.024 19 44 .. 74 99 .. 60 103 .. 0.85 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 2.8e-06 Phospholip_A2_4 19 kgkPvnevDaaarlHDiaYsqykdsg 44 gkPv+++D +++HD+ Ys+ ++g FUN_000579-T1 74 SGKPVDQTDRCCLEHDLCYSKIRNDG 99 47******************987765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (173 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 880 (0.034449); expected 510.9 (0.02) Passed bias filter: 383 (0.0149931); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1714.14 // Query: FUN_000580-T1 [L=503] Description: FUN_000580 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-12 46.1 4.0 4.6e-12 46.0 2.3 2.0 2 HLH Helix-loop-helix DNA-binding domain 2.1e-09 37.9 2.0 8.3e-09 36.0 2.3 1.9 2 Hairy_orange Hairy Orange ------ inclusion threshold ------ 0.14 12.6 0.1 0.27 11.7 0.1 1.5 1 bHLH_NPAS4 NPAS4 bHLH domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.0 2.3 5.5e-16 4.6e-12 4 53 .] 42 91 .. 40 91 .. 0.98 2 ? -3.5 0.0 1.6 1.4e+04 18 28 .. 162 172 .. 160 188 .. 0.69 Alignments for each domain: == domain 1 score: 46.0 bits; conditional E-value: 5.5e-16 HLH 4 ahnerERrRrdriNdafdeLrellPtlppdkKlsKaeiLrlAieYIkqLq 53 +h E+rRrdr+N +++e +llP++ + k ++KaeiL+++i YIk+Lq FUN_000580-T1 42 SHKLTEKRRRDRMNISMSEIAQLLPSSAEPKQMEKAEILEKTIIYIKKLQ 91 6999*********************************************8 PP == domain 2 score: -3.5 bits; conditional E-value: 1.6 HLH 18 dafdeLrellP 28 ++f +L +l+ FUN_000580-T1 162 SCFRRLMVHLQ 172 78888888887 PP >> Hairy_orange Hairy Orange # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 1.3 1.1e+04 10 20 .. 58 68 .. 57 72 .. 0.83 2 ! 36.0 2.3 9.8e-13 8.3e-09 2 39 .. 136 175 .. 135 176 .. 0.96 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 1.3 Hairy_orange 10 akEVsryLstv 20 ++E+++ L ++ FUN_000580-T1 58 MSEIAQLLPSS 68 89*****9876 PP == domain 2 score: 36.0 bits; conditional E-value: 9.8e-13 Hairy_orange 2 fraGFreCakEVsryLstvegvds.dlr.srLlsHLqrcl 39 +++GFr+C+kEV + L++ve +d + + rL+ HLq+ l FUN_000580-T1 136 YCSGFRDCIKEVFHCLTNVEAMDLqQSCfRRLMVHLQHEL 175 9************************99**********976 PP >> bHLH_NPAS4 NPAS4 bHLH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 3.2e-05 0.27 6 52 .. 44 89 .. 40 91 .. 0.81 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3.2e-05 bHLH_NPAS4 6 kGAskaRRDqinvEirkLkDLLPlsDlikdRLsyLqvmsLaCiyiRk 52 k k RRD +n+ + ++ LLP s + + +++ + iyi+k FUN_000580-T1 44 KLTEKRRRDRMNISMSEIAQLLPSSA-EPKQMEKAEILEKTIIYIKK 89 55679******************775.55567888888888888887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (503 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 946 (0.0370327); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4812.07 // Query: FUN_000582-T1 [L=172] Description: FUN_000582 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-27 94.8 13.7 7.7e-27 94.5 13.7 1.1 1 Phospholip_A2_1 Phospholipase A2 ------ inclusion threshold ------ 0.13 12.8 15.0 93 3.7 15.0 2.4 1 Phospholip_A2_2 Phospholipase A2 0.14 12.9 0.0 0.26 12.1 0.0 1.4 1 Phospholip_A2_4 Phospholipase A2-like domain Domain annotation for each model (and alignments): >> Phospholip_A2_1 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 94.5 13.7 9.1e-31 7.7e-27 2 108 .. 53 163 .. 52 165 .. 0.82 Alignments for each domain: == domain 1 score: 94.5 bits; conditional E-value: 9.1e-31 Phospholip_A2_1 2 lqlekmikcvtgkeallsyesYGcycglggkgtpvdatdrCClahdcCyeklkk.kgckepklekykvsvskke.itckse....kkslcekql 89 +q++ mi c+ g+ ++l+y YGcycg+gg+g p+d+ drCC++hd+Cy+++ c + y + +++k+ +c+++ +c+++l FUN_000582-T1 53 IQFGLMIACHVGR-NPLEYVGYGCYCGIGGEGVPKDQSDRCCQQHDQCYNSVIAsGVC-PLDTAVYLMPYKRKNcYECETAsyywFYGECRETL 144 79***********.9*************************************884677.444555555444433245655444446789***** PP Phospholip_A2_1 90 CeCDkaaaeClakatynkk 108 C+CD +a++C++++++n++ FUN_000582-T1 145 CKCDSEAVQCFKRSKFNTA 163 ***************9975 PP >> Phospholip_A2_2 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 15.0 0.011 93 24 60 .. 87 125 .. 74 167 .. 0.66 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.011 Phospholip_A2_2 24 ketDkCCreHDhceekieal.eskygltnk.slftishC 60 ++ D+CC++HD+c +++ a + + + +++ +C FUN_000582-T1 87 DQSDRCCQQHDQCYNSVIASgVCPLDTAVYlMPYKRKNC 125 678**********98765431333322222133444444 PP >> Phospholip_A2_4 Phospholipase A2-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 3.1e-05 0.26 19 46 .. 82 109 .. 64 115 .. 0.77 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.1e-05 Phospholip_A2_4 19 kgkPvnevDaaarlHDiaYsqykdsgkn 46 +g P +++D +++HD Y+ + sg FUN_000582-T1 82 EGVPKDQSDRCCQQHDQCYNSVIASGVC 109 469*****************99988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (172 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 845 (0.0330789); expected 510.9 (0.02) Passed bias filter: 357 (0.0139753); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1696.14 // Query: FUN_000583-T1 [L=179] Description: FUN_000583 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-27 96.8 17.6 1.9e-27 96.4 17.6 1.2 1 Phospholip_A2_1 Phospholipase A2 0.0036 18.0 0.2 0.008 16.9 0.2 1.6 1 Phospholip_A2_4 Phospholipase A2-like domain ------ inclusion threshold ------ 0.78 10.4 14.1 1.3e+02 3.2 14.2 2.5 1 Phospholip_A2_2 Phospholipase A2 Domain annotation for each model (and alignments): >> Phospholip_A2_1 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.4 17.6 2.2e-31 1.9e-27 1 108 [. 50 157 .. 50 159 .. 0.87 Alignments for each domain: == domain 1 score: 96.4 bits; conditional E-value: 2.2e-31 Phospholip_A2_1 1 llqlekmikcvtgkeallsyesYGcycglggkgtpvdatdrCClahdcCyeklkk.kgckepklekykvsvskkeitckse..kkslcekqlCe 91 l+q++ mi c t++ + sy +YGcycg+gg g+pvd+td+CC+ hd+Cy+++++ k c + +++ ++v +++ tc+ + +c++++Ce FUN_000583-T1 50 LVQFHLMIACETNR-TSSSYYDYGCYCGYGGGGEPVDETDKCCQIHDKCYDAVNDaKLC--TFSSSIYWRVYSRDGTCTGCadPEGTCKRAICE 140 689***********.99************************************997888..66666666666666666554335789******* PP Phospholip_A2_1 92 CDkaaaeClakatynkk 108 CD aa +C+++a+yn++ FUN_000583-T1 141 CDGAASRCFKHAKYNEE 157 ***************97 PP >> Phospholip_A2_4 Phospholipase A2-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.2 9.4e-07 0.008 20 44 .. 81 105 .. 67 113 .. 0.85 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 9.4e-07 Phospholip_A2_4 20 gkPvnevDaaarlHDiaYsqykdsg 44 g+Pv+e+D +++HD+ Y+ d + FUN_000583-T1 81 GEPVDETDKCCQIHDKCYDAVNDAK 105 69*****************999876 PP >> Phospholip_A2_2 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 14.2 0.016 1.3e+02 24 44 .. 85 105 .. 59 160 .. 0.78 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.016 Phospholip_A2_2 24 ketDkCCreHDhceekieale 44 +etDkCC+ HD+c + ++ + FUN_000583-T1 85 DETDKCCQIHDKCYDAVNDAK 105 689***********9997654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 784 (0.0306909); expected 510.9 (0.02) Passed bias filter: 330 (0.0129184); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.23u 0.39s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1871.69 // Query: FUN_000584-T1 [L=310] Description: FUN_000584 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-29 103.4 15.4 5e-29 102.1 15.4 1.7 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.002 18.1 10.9 0.0045 16.9 10.9 1.7 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.035 14.4 11.9 3.1 8.0 1.2 3.0 2 7tm_4 Olfactory receptor 0.12 12.9 0.0 0.47 11.0 0.0 2.0 2 DEATH_SH3BP4 SH3BP4, DEATH domain-like 0.67 11.0 3.2 15 6.7 0.1 2.7 2 DUF5489 Family of unknown function (DUF5489) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.1 15.4 9.8e-33 5e-29 14 260 .] 3 232 .. 1 232 [. 0.88 Alignments for each domain: == domain 1 score: 102.1 bits; conditional E-value: 9.8e-33 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 14 klrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkrralvlilvv 109 +lrt tn f+++La++D+lv+ ++l ++ + ++ + g + ++++l++++l+as+ +lta+++DR+la ++p++y++i ++ + +++++ FUN_000584-T1 3 HLRTHTNGFIVSLAMSDILVG-ITLFLHYALNV---H---GPL---ALNVLYTTSLLASVTNLTAVTFDRHLACTQPFNYSNIIA-KHFTKIVVFC 87 89*******************.66665554444...2...333...5799******************************99777.788889999* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxx RF 7tm_1 110 WvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks............kkkk 193 W++a++ sl+pl + +++ +s + +y++++++lg p++ i+++y ri+r ++k k+ek+ ++ + FUN_000584-T1 88 WIAAVTTSLLPLSWANSEPSS-------A-AL-------ALHVYQVCILILGITAPFVWIFFSYLRIFRQVSKIVKREKKiaksvmyahepcERGR 168 ***********9955443332.......1.22.......3458*************************************8888888888886667 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 194 sarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ +e+k++k+l v+ v+fvl wlP+ ++l+ ++ + + ++e+++ ++ l + s++NP++Y FUN_000584-T1 169 RVCSEAKIAKILSVIAVMFVLSWLPIIWTTLVYAI---GQPRLFPEALKYVSPLTLALGSIVNPVLY 232 777788*****************************...****************************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 10.9 8.9e-07 0.0045 20 252 .. 3 242 .. 1 247 [. 0.72 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 8.9e-07 7TM_GPCR_Srsx 20 kLrskssiLicvqcladllclvgelvfvvllltgtqlkreeCFlliivyvfgltaqsvllLvigiDlliavkfPirYrllskekYllillifpvly 115 +Lr+ ++ i+ ++++d+l+ + ++ +l++ + l+++y+ +l+a+ + l ++++D+ +a++ P++Y+++ ++++ i ++f+ + FUN_000584-T1 3 HLRTHTNGFIVSLAMSDILVGITLFLHYALNV-------HGPLALNVLYTTSLLASVTNLTAVTFDRHLACTQPFNYSNIIAKHFTKI-VVFCWIA 90 57777888888888888777777766666666.......555679999*********************************9977665.6788889 PP 7TM_GPCR_Srsx 116 ssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek......................kkssskkvlksl 189 ++++ +l +++e ala +++++ l i + +v + ++ +i+++ ++ + +s k+ k l FUN_000584-T1 91 AVTTSLLPLSWANSE-----PSSAALALHVYQVCILILGITAPFVWI-FFSYLRIFRQVSKIvkrekkiaksvmyahepcergrRVCSEAKIAKIL 180 999999999999999.....445566556666655544444444443.3344455565555567788899*************999********** PP 7TM_GPCR_Srsx 190 kvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrka 252 +v v+f+++W+ +i t+++a+ + + + + ++ +++ l + n + + ++ +++r+ FUN_000584-T1 181 SVIAVMFVLSWLP-IIWTTLVYAIGQPRLFPEALKYVSPLTLALGSIVNPVLYSLKKPDFRHV 242 ***********75.4555566666655555555555555555555555666666666666665 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 1.2 0.0006 3.1 44 123 .. 14 92 .. 9 103 .. 0.71 2 ? 7.5 3.7 0.00085 4.4 167 278 .. 115 248 .. 99 249 .. 0.61 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0006 7tm_4 44 sastlPtvlGiflvdareisfeacllqlffihkfslles.avllamavdrfvaiysplryteiltnkvisriglvvlvrsv 123 s++ ++Gi l+ + + l+ + +++ sll s + l a+++dr+ a +p++y++i +++ ++i + + +v FUN_000584-T1 14 SLAMSDILVGITLFLHYALNVHGPLALNV-LYTTSLLASvTNLTAVTFDRHLACTQPFNYSNIIAKH-FTKIVVFCWIAAV 92 55555567788888888888888888877.555555555167899******************9987.5555555555444 PP == domain 2 score: 7.5 bits; conditional E-value: 0.00085 7tm_4 167 iyGlfvvvstlgldsllivlsyglilrtvlgiasreerk.kal....ntc.......g....shvcavlaf.....yvPmiglsvvhrfgk..kvs 239 +y + +++ ++ + i +sy i+r v +i re++ k++ + c + ++++ v+a + P+i ++v+ +g+ + FUN_000584-T1 115 VYQVCILILGITAPFVWIFFSYLRIFRQVSKIVKREKKIaKSVmyahEPCergrrvcSeakiAKILSVIAVmfvlsWLPIIWTTLVYAIGQprLFP 210 566666666666666777777777777777777776653233211112332211111211112222222211112268999999999999631345 PP 7tm_4 240 rllqvllanlyllfPPvlnPivysvktkeirdavvkill 278 + l+ ++ l l + ++nP++ys+k + r++ k+ + FUN_000584-T1 211 EALKY-VSPLTLALGSIVNPVLYSLKKPDFRHVCNKMCC 248 55554.57788999*************999999999865 PP >> DEATH_SH3BP4 SH3BP4, DEATH domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 9.3e-05 0.47 18 81 .. 120 183 .. 112 186 .. 0.91 2 ? -2.8 0.0 1.8 9.3e+03 39 58 .. 197 216 .. 194 220 .. 0.77 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 9.3e-05 DEATH_SH3BP4 18 vLleqialPfkkltYiYsavrtlvtekvksWkaladalgysklslddltraeaekeaekvasvl 81 +L+ i+ Pf + + Y + v++ vk k +a+++ y + + ++ r+ e + k+ sv+ FUN_000584-T1 120 ILILGITAPFVWIFFSYLRIFRQVSKIVKREKKIAKSVMYAHEPCERGRRVCSEAKIAKILSVI 183 5777899******************************************999999988888776 PP == domain 2 score: -2.8 bits; conditional E-value: 1.8 DEATH_SH3BP4 39 tlvtekvksWkaladalgys 58 t+++ + + + + +al y FUN_000584-T1 197 TTLVYAIGQPRLFPEALKYV 216 66777788889999999996 PP >> DUF5489 Family of unknown function (DUF5489) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.1 0.0029 15 36 64 .. 118 146 .. 111 154 .. 0.87 2 ? 4.0 0.4 0.021 1.1e+02 35 60 .. 175 197 .. 169 204 .. 0.67 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0029 DUF5489 36 ipaiitgiasafvlmfmdflplfwgiaii 64 + +i gi++ fv +f+ +l +f ++ i FUN_000584-T1 118 VCILILGITAPFVWIFFSYLRIFRQVSKI 146 567899*****************887755 PP == domain 2 score: 4.0 bits; conditional E-value: 0.021 DUF5489 35 kipaiitgiasafvlmfmdflplfwg 60 ki i++ ia fvl +lp++w FUN_000584-T1 175 KIAKILSVIAVMFVL---SWLPIIWT 197 566666666666555...67899996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (310 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1056 (0.0413388); expected 510.9 (0.02) Passed bias filter: 500 (0.0195733); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3039.57 // Query: FUN_000585-T1 [L=326] Description: FUN_000585 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0026 17.8 0.5 0.012 15.7 0.5 2.1 1 CUE CUE domain ------ inclusion threshold ------ 0.058 13.8 0.1 0.13 12.6 0.1 1.6 1 Nup54_C Nup54 C-terminal interacting domain Domain annotation for each model (and alignments): >> CUE CUE domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.5 9.3e-07 0.012 3 36 .. 172 205 .. 170 206 .. 0.94 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 9.3e-07 CUE 3 smletLkemFPdldeevIravLeasngnvEaain 36 +++++L emFP+ + I+++L + ngn Eaa++ FUN_000585-T1 172 DEVSVLLEMFPEACSLEIEQCLNDANGNTEAAVH 205 6899****************************95 PP >> Nup54_C Nup54 C-terminal interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 1e-05 0.13 3 18 .. 1 16 [. 1 28 [. 0.93 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1e-05 Nup54_C 3 mdadlqdeiKQfLkme 18 m+ad+ +e+KQfLk + FUN_000585-T1 1 MEADVERELKQFLKHQ 16 99************87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (326 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1285 (0.0503034); expected 510.9 (0.02) Passed bias filter: 659 (0.0257976); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 3352.86 // Query: FUN_000586-T1 [L=705] Description: FUN_000586 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-38 132.0 2.1 5.2e-38 131.5 0.8 1.9 2 VWA von Willebrand factor type A domain 5e-12 46.9 0.0 1.6e-11 45.3 0.0 1.9 1 VWA_2 von Willebrand factor type A domain ------ inclusion threshold ------ 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 Copine Copine 0.018 15.7 0.0 1.9 9.2 0.0 2.5 2 DUF3861 Domain of Unknown Function with PDB structure (DUF3 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 DUF3289 Protein of unknown function (DUF3289) Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.1 5.8e+03 49 76 .. 278 305 .. 270 315 .. 0.80 2 ! 131.5 0.8 1e-41 5.2e-38 1 171 [. 358 532 .. 358 535 .. 0.96 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.1 VWA 49 vrtefslndysskeellsavkslkykgg 76 + f++++ +k+ l++++k + ++ + FUN_000586-T1 278 CKRKFKFKELVKKDRLIDQIKGMAFALH 305 5778999999999*******99966655 PP == domain 2 score: 131.5 bits; conditional E-value: 1e-41 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrtefslndysskeellsavkslkykgggttntgkalkyalenlfkss 96 +ivf++D+Sgsi+++n +k k+f++++++++di+p+++rv++v y+s++ + +++y sk+ l+ avk+l y +ggt+ t++al+ ++ n+++++ FUN_000586-T1 358 NIVFVMDESGSIKYSNYQKEKKFVSEMIQKFDISPRQARVAIVEYASSASLSVAFDNYGSKTRLMCAVKDLGYLEGGTN-TAQALEVTQYNVLEPA 452 7******************************************************************************.************9999 PP VWA 97 agaRe...gapkvvvlltdGksqd.gdveeaarelksa..gvkvfavgvgnadeeeLekiasepdeghvftvedfealeel 171 + + ++vv+ltdGks+d g+ ++aa +lk+ + +v+avgv n + eL++ia++p +hvft++df++l +l FUN_000586-T1 453 LANPVgdvETVQIVVVLTDGKSDDqGETKDAATNLKKGikDLTVIAVGVANYNFPELREIATDPE-THVFTAKDFDELLNL 532 996668899*************9967**********9888************************9.**********98766 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.3 0.0 3.1e-15 1.6e-11 1 107 [. 359 472 .. 359 473 .. 0.88 Alignments for each domain: == domain 1 score: 45.3 bits; conditional E-value: 3.1e-15 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallksl...p.gdrvglvtfsdnpevliplt..kdkakllealrrleatgggtdlaaAlqlarkalk 90 +vfv+D SgS+ + ++++ k++v+++++++ p + rv++v +++++ + + ++ +k++l+ a++ l +ggt++a+Al++ + + FUN_000586-T1 359 IVFVMDESGSIKYS-----NYQKEKKFVSEMIQKFdisPrQARVAIVEYASSASLSVAFDnyGSKTRLMCAVKDLGYLEGGTNTAQALEVTQYNVL 449 69**********99.....8*************888885477*********9999999976799************99***********9996554 PP VWA_2 91 krr......rknakriivlitDg 107 + + + +i+v++tDg FUN_000586-T1 450 EPAlanpvgDVETVQIVVVLTDG 472 34457788889999********9 PP >> Copine Copine # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 5.2e-06 0.026 103 159 .. 457 515 .. 430 526 .. 0.82 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 5.2e-06 Copine 103 tkeasqYfvLliitDGvvtdmketidaiveAsk..lplSiiivGvGdadfeemrelddd 159 + + + ++++++tDG d+ et+da + k l +i vGv + +f e+re+ d FUN_000586-T1 457 VGDVETVQIVVVLTDGKSDDQGETKDAATNLKKgiKDLTVIAVGVANYNFPELREIATD 515 56677889*******************9876653379****************998776 PP >> DUF3861 Domain of Unknown Function with PDB structure (DUF3861) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.0 0.00038 1.9 19 62 .. 44 87 .. 33 89 .. 0.90 2 ? 3.6 0.0 0.021 1.1e+02 20 44 .. 516 540 .. 507 545 .. 0.84 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00038 DUF3861 19 eeaplefeaenhddlleivervkkkrqldadeaaalavglkLlg 62 ++p+++++ d +e+ve+++++ d+d+ ++++ ++Llg FUN_000586-T1 44 RSEPIKYDIYTLDHFIELVEKIERNTTTDKDTLKKVINYIRLLG 87 3459********************************99999997 PP == domain 2 score: 3.6 bits; conditional E-value: 0.021 DUF3861 20 eaplefeaenhddlleivervkkkr 44 ++ f+a++ d+ll++v+ ++kk FUN_000586-T1 516 PETHVFTAKDFDELLNLVASLRKKA 540 45788*****************986 PP >> DUF3289 Protein of unknown function (DUF3289) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 5e-05 0.25 159 202 .. 270 313 .. 259 327 .. 0.80 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 5e-05 DUF3289 159 yldenksslkkaikdskLPkfnrladrinGlgisvhdiyatkik 202 + d+ s k+ k +L k +rl+d+i G++ ++hd y+ +++ FUN_000586-T1 270 LYDTSYASCKRKFKFKELVKKDRLIDQIKGMAFALHDKYSSQLT 313 5566667777888888999*********************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (705 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 680 (0.0266197); expected 510.9 (0.02) Passed bias filter: 615 (0.0240752); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6717.06 // Query: FUN_000586-T2 [L=712] Description: FUN_000586 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-37 128.6 0.9 8.5e-37 127.5 0.9 1.6 1 VWA von Willebrand factor type A domain 9.1e-13 49.2 0.0 2.2e-12 48.0 0.0 1.6 1 VWA_2 von Willebrand factor type A domain 0.0034 18.1 1.8 0.02 15.6 0.1 2.5 3 Methylase_S Type I restriction modification DNA specificity 0.0071 16.3 0.0 0.014 15.3 0.0 1.4 1 Copine Copine ------ inclusion threshold ------ 0.098 13.4 0.0 9.6 7.0 0.0 2.5 2 DUF3861 Domain of Unknown Function with PDB structure (D 0.25 11.8 0.2 1.9 9.0 0.0 2.4 2 PUA PUA domain Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 127.5 0.9 2e-40 8.5e-37 1 171 [. 365 539 .. 365 542 .. 0.95 Alignments for each domain: == domain 1 score: 127.5 bits; conditional E-value: 2e-40 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrtefslndysskeellsavkslkykgggttntgkalkyalenlfkss 96 +ivf++D+Sgsig++n +k k+f++++++++di+p+++rv++v y+s++ + +++y s++ l+ avk+l y+gggt+ t++al+ ++ n+++++ FUN_000586-T2 365 NIVFVMDESGSIGYSNYQKEKQFVSEMIQKFDISPRQARVAIVEYASSASLSVAFDNYGSQKRLMCAVKALGYSGGGTN-TAEALRVTQYNVLEPA 459 7******************************************************************************.********99999999 PP VWA 97 agaRe...gapkvvvlltdGksqd.gdveeaarelksa..gvkvfavgvgnadeeeLekiasepdeghvftvedfealeel 171 + + ++vv+ltdG+s+ ++ ++aa +lk+ + +v+avgv n + eL++ia+++ +hvft++df++l +l FUN_000586-T2 460 LANPLgdvETVQIVVVLTDGRSNNqEETKDAATNLKKGikDLTVIAVGVANYNFPELREIATNSE-THVFTAKDFDELLSL 539 995558899*************8845**********9888********************99998.**********98666 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.0 0.0 5.2e-16 2.2e-12 1 107 [. 366 479 .. 366 480 .. 0.89 Alignments for each domain: == domain 1 score: 48.0 bits; conditional E-value: 5.2e-16 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallksl...p.gdrvglvtfsdnpevliplt..kdkakllealrrleatgggtdlaaAlqlarkalk 90 +vfv+D SgS++ + ++++ k++v+++++++ p + rv++v +++++ + + ++ ++++l+ a+++l +gggt++a+Al++ + + FUN_000586-T2 366 IVFVMDESGSIGYS-----NYQKEKQFVSEMIQKFdisPrQARVAIVEYASSASLSVAFDnyGSQKRLMCAVKALGYSGGGTNTAEALRVTQYNVL 456 69**********99.....8*************888885477*********9999999976799************99***********9996554 PP VWA_2 91 krr......rknakriivlitDg 107 + + + +i+v++tDg FUN_000586-T2 457 EPAlanplgDVETVQIVVVLTDG 479 444577888899999*******9 PP >> Methylase_S Type I restriction modification DNA specificity domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 2.4 1e+04 15 31 .. 61 81 .. 47 85 .. 0.54 2 ! 15.6 0.1 4.7e-06 0.02 12 90 .. 319 396 .. 316 409 .. 0.89 3 ? 0.6 0.0 0.19 7.9e+02 36 111 .. 477 547 .. 465 560 .. 0.65 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 2.4 Methylase_S 15 i....kkgktpkkkelkekgk 31 + ++++t +k+ lk++ + FUN_000586-T2 61 LvekiERNTTTNKDTLKKVID 81 222246666666666666555 PP == domain 2 score: 15.6 bits; conditional E-value: 4.7e-06 Methylase_S 12 vfeikkgktpkkkelkekgkypyiragdlnnkvvkgglgykkkyilpknsilissr.atiGkvfyrdkkyytnqsiivle 90 + +i+++ +p+++++ + ++py+++ + + v +++++k+++ +p n + ++ ++iG+ +y+++k +++ i+++ FUN_000586-T2 319 LTNIASTDIPSSAKDIGEKFFPYFETMTGST--VCSTVETKEDCEIPANIVFVMDEsGSIGYSNYQKEKQFVSEMIQKFD 396 66888999999999999999****9995555..**************9999999888************99999999886 PP == domain 3 score: 0.6 bits; conditional E-value: 0.19 Methylase_S 36 ragdlnnkvvkgglgykkkyilp.knsilissratiGkvfyrdkkyytnqsiivlepkn.kkkiteflylylllklkk 111 + g+ nn ++ ++ + +++ + +++++ + + + + f ++ tn++ +v++ k+ + e l l +l +k+ FUN_000586-T2 477 TDGRSNN---QEETKDAATNLKKgIKDLTVIAVGVANYNFPELREIATNSETHVFTAKDfD----ELLSLVASLRKKA 547 5554555...344444444444456788888766666666666689999999999998744....4455555555555 PP >> Copine Copine # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 3.3e-06 0.014 105 159 .. 466 522 .. 441 533 .. 0.85 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.3e-06 Copine 105 easqYfvLliitDGvvtdmketidaiveAsk..lplSiiivGvGdadfeemrelddd 159 + + ++++++tDG +++et+da + k l +i vGv + +f e+re+ + FUN_000586-T2 466 DVETVQIVVVLTDGRSNNQEETKDAATNLKKgiKDLTVIAVGVANYNFPELREIATN 522 566779*******************9876653379****************999877 PP >> DUF3861 Domain of Unknown Function with PDB structure (DUF3861) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.0022 9.6 20 62 .. 45 87 .. 37 88 .. 0.89 2 ? 3.5 0.0 0.027 1.1e+02 19 44 .. 522 547 .. 514 552 .. 0.84 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0022 DUF3861 20 eaplefeaenhddlleivervkkkrqldadeaaalavglkLlg 62 ++p+++++ d +e+ve+++++ ++d+ ++++ ++Llg FUN_000586-T2 45 SEPIKYDIYTLDHFIELVEKIERNTTTNKDTLKKVIDYIRLLG 87 459******************************9998888886 PP == domain 2 score: 3.5 bits; conditional E-value: 0.027 DUF3861 19 eeaplefeaenhddlleivervkkkr 44 ++++ f+a++ d+ll++v+ ++kk FUN_000586-T2 522 NSETHVFTAKDFDELLSLVASLRKKA 547 456889*****************986 PP >> PUA PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.52 2.2e+03 38 52 .. 141 155 .. 136 157 .. 0.86 2 ? 9.0 0.0 0.00044 1.9 19 63 .. 455 520 .. 443 527 .. 0.71 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.52 PUA 38 vvvdekgelvAvGla 52 vv++ ++e +A+G+ FUN_000586-T2 141 VVLTADNETIAIGRI 155 5788899******96 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00044 PUA 19 LlapGvvevdgefrkgdeVvvvdekg.....................elvAvGlanysseelekie 63 +l p + g+++ ++Vvv++ ++ +++AvG+any+ el++i FUN_000586-T2 455 VLEPALANPLGDVETVQIVVVLTDGRsnnqeetkdaatnlkkgikdlTVIAVGVANYNFPELREIA 520 5555555666666666777777774356666667777777777777799**************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (712 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 686 (0.0268546); expected 510.9 (0.02) Passed bias filter: 603 (0.0236054); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.40u 0.37s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6906.66 // Query: FUN_000586-T3 [L=594] Description: FUN_000586 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-37 128.9 0.9 6.1e-37 128.0 0.9 1.5 1 VWA von Willebrand factor type A domain 7.3e-13 49.5 0.0 1.7e-12 48.4 0.0 1.6 1 VWA_2 von Willebrand factor type A domain 0.0013 19.4 0.4 0.015 16.0 0.1 2.1 2 Methylase_S Type I restriction modification DNA specificity 0.0056 16.7 0.0 0.011 15.7 0.0 1.4 1 Copine Copine ------ inclusion threshold ------ 0.18 12.2 0.3 1.5 9.3 0.0 2.5 3 PUA PUA domain Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 128.0 0.9 1.2e-40 6.1e-37 1 171 [. 247 421 .. 247 424 .. 0.95 Alignments for each domain: == domain 1 score: 128.0 bits; conditional E-value: 1.2e-40 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrtefslndysskeellsavkslkykgggttntgkalkyalenlfkss 96 +ivf++D+Sgsig++n +k k+f++++++++di+p+++rv++v y+s++ + +++y s++ l+ avk+l y+gggt+ t++al+ ++ n+++++ FUN_000586-T3 247 NIVFVMDESGSIGYSNYQKEKQFVSEMIQKFDISPRQARVAIVEYASSASLSVAFDNYGSQKRLMCAVKALGYSGGGTN-TAEALRVTQYNVLEPA 341 7******************************************************************************.********99999999 PP VWA 97 agaRe...gapkvvvlltdGksqd.gdveeaarelksa..gvkvfavgvgnadeeeLekiasepdeghvftvedfealeel 171 + + ++vv+ltdG+s+ ++ ++aa +lk+ + +v+avgv n + eL++ia+++ +hvft++df++l +l FUN_000586-T3 342 LANPLgdvETVQIVVVLTDGRSNNqEETKDAATNLKKGikDLTVIAVGVANYNFPELREIATNSE-THVFTAKDFDELLSL 421 995558899*************8845**********9888********************99998.**********98666 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.4 0.0 3.3e-16 1.7e-12 1 107 [. 248 361 .. 248 362 .. 0.89 Alignments for each domain: == domain 1 score: 48.4 bits; conditional E-value: 3.3e-16 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallksl...p.gdrvglvtfsdnpevliplt..kdkakllealrrleatgggtdlaaAlqlarkalk 90 +vfv+D SgS++ + ++++ k++v+++++++ p + rv++v +++++ + + ++ ++++l+ a+++l +gggt++a+Al++ + + FUN_000586-T3 248 IVFVMDESGSIGYS-----NYQKEKQFVSEMIQKFdisPrQARVAIVEYASSASLSVAFDnyGSQKRLMCAVKALGYSGGGTNTAEALRVTQYNVL 338 69**********99.....8*************888885477*********9999999976799************99***********9996554 PP VWA_2 91 krr......rknakriivlitDg 107 + + + +i+v++tDg FUN_000586-T3 339 EPAlanplgDVETVQIVVVLTDG 361 444577888899999*******9 PP >> Methylase_S Type I restriction modification DNA specificity domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.1 3e-06 0.015 12 90 .. 201 278 .. 198 291 .. 0.89 2 ? 1.0 0.0 0.12 6e+02 35 112 .. 358 430 .. 347 443 .. 0.65 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 3e-06 Methylase_S 12 vfeikkgktpkkkelkekgkypyiragdlnnkvvkgglgykkkyilpknsilissr.atiGkvfyrdkkyytnqsiivle 90 + +i+++ +p+++++ + ++py+++ + + v +++++k+++ +p n + ++ ++iG+ +y+++k +++ i+++ FUN_000586-T3 201 LTNIASTDIPSSAKDIGEKFFPYFETMTGST--VCSTVETKEDCEIPANIVFVMDEsGSIGYSNYQKEKQFVSEMIQKFD 278 6688899999999999999*****9995555..**************9999999888************99999999886 PP == domain 2 score: 1.0 bits; conditional E-value: 0.12 Methylase_S 35 iragdlnnkvvkgglgykkkyilp.knsilissratiGkvfyrdkkyytnqsiivlepkn.kkkiteflylylllklkkl 112 ++ g+ nn ++ ++ + +++ + +++++ + + + + f ++ tn++ +v++ k+ + e l l +l +k++ FUN_000586-T3 358 LTDGRSNN---QEETKDAATNLKKgIKDLTVIAVGVANYNFPELREIATNSETHVFTAKDfD----ELLSLVASLRKKAC 430 45554555...3444444444444567888887666666666666899999*****998744....44555555555555 PP >> Copine Copine # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 2.2e-06 0.011 105 159 .. 348 404 .. 323 415 .. 0.85 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2.2e-06 Copine 105 easqYfvLliitDGvvtdmketidaiveAsk..lplSiiivGvGdadfeemrelddd 159 + + ++++++tDG +++et+da + k l +i vGv + +f e+re+ + FUN_000586-T3 348 DVETVQIVVVLTDGRSNNQEETKDAATNLKKgiKDLTVIAVGVANYNFPELREIATN 404 566779*******************9876653379****************999877 PP >> PUA PUA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 0.38 1.9e+03 38 52 .. 23 37 .. 20 39 .. 0.87 2 ? -3.9 0.0 3.9 2e+04 35 44 .. 247 256 .. 244 258 .. 0.81 3 ? 9.3 0.0 0.00029 1.5 18 63 .. 336 402 .. 325 409 .. 0.71 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.38 PUA 38 vvvdekgelvAvGla 52 vv++ ++e +A+G+ FUN_000586-T3 23 VVLTADNETIAIGRI 37 588899*******96 PP == domain 2 score: -3.9 bits; conditional E-value: 3.9 PUA 35 deVvvvdekg 44 +V v+de g FUN_000586-T3 247 NIVFVMDESG 256 6899***987 PP == domain 3 score: 9.3 bits; conditional E-value: 0.00029 PUA 18 sLlapGvvevdgefrkgdeVvvvdekg.....................elvAvGlanysseelekie 63 ++l p + g+++ ++Vvv++ ++ +++AvG+any+ el++i FUN_000586-T3 336 NVLEPALANPLGDVETVQIVVVLTDGRsnnqeetkdaatnlkkgikdlTVIAVGVANYNFPELREIA 402 55555556666666666777777774356666677777777777777799**************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (594 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 708 (0.0277158); expected 510.9 (0.02) Passed bias filter: 621 (0.02431); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5767.14 // Query: FUN_000587-T1 [L=386] Description: FUN_000587 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-13 49.1 0.4 22 5.6 0.0 10.0 15 ETF_alpha Electron transfer flavoprotein FAD-binding do 4e-12 46.7 29.6 4.4 8.1 0.2 10.9 14 Ig_SMCHD1_4th SMCHD1 Ig-like domain 4 2.8e-05 24.5 0.0 3.3 8.0 0.0 3.7 4 Drf_FH1 Formin Homology Region 1 ------ inclusion threshold ------ 0.016 15.1 19.5 65 3.3 0.2 9.2 13 BMF Bcl-2-modifying factor, apoptosis 0.38 10.1 0.7 1.2e+02 1.9 0.0 4.9 8 Glyphos_transf CDP-Glycerol:Poly(glycerophosphate) glyceroph Domain annotation for each model (and alignments): >> ETF_alpha Electron transfer flavoprotein FAD-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.023 1.2e+02 41 70 .. 27 56 .. 23 63 .. 0.81 2 ? 3.0 0.0 0.027 1.4e+02 42 71 .. 40 69 .. 38 76 .. 0.79 3 ? 3.2 0.0 0.024 1.2e+02 41 70 .. 51 80 .. 48 87 .. 0.81 4 ? 2.6 0.0 0.036 1.8e+02 55 71 .. 89 105 .. 69 114 .. 0.70 5 ? 4.3 0.0 0.011 55 50 71 .. 108 129 .. 97 147 .. 0.54 6 ? 3.3 0.0 0.022 1.1e+02 41 71 .. 147 177 .. 143 184 .. 0.81 7 ? 3.2 0.0 0.023 1.2e+02 41 70 .. 159 188 .. 155 193 .. 0.80 8 ! 5.6 0.0 0.0043 22 45 71 .. 187 213 .. 179 234 .. 0.59 9 ? 0.8 0.0 0.13 6.7e+02 53 70 .. 243 260 .. 231 267 .. 0.71 10 ? 3.2 0.0 0.025 1.3e+02 41 70 .. 243 272 .. 239 279 .. 0.80 11 ? 3.4 0.0 0.021 1.1e+02 41 71 .. 279 309 .. 275 317 .. 0.81 12 ? 3.3 0.0 0.022 1.1e+02 41 70 .. 291 320 .. 287 327 .. 0.80 13 ? 3.3 0.0 0.022 1.1e+02 41 70 .. 303 332 .. 297 337 .. 0.79 14 ? 3.4 0.0 0.021 1.1e+02 41 71 .. 315 345 .. 312 354 .. 0.80 15 ? 4.4 0.0 0.01 52 47 71 .. 333 357 .. 323 372 .. 0.54 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.023 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGi 70 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 27 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGV 56 567788888888888899999999999998 PP == domain 2 score: 3.0 bits; conditional E-value: 0.027 ETF_alpha 42 vdagwlpkerqvGqtGktvaPklyiavGis 71 +d g++++ + v G t +P+l+i +G+ FUN_000587-T1 40 IDCGVTDRPNLVIDCGVTDRPNLVIDCGVT 69 577788888888888999999999999985 PP == domain 3 score: 3.2 bits; conditional E-value: 0.024 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGi 70 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 51 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGV 80 457788888888888899999999999998 PP == domain 4 score: 2.6 bits; conditional E-value: 0.036 ETF_alpha 55 qtGktvaPklyiavGis 71 G t +P+l+i +G+ FUN_000587-T1 89 DCGVTYRPNLVIDCGVT 105 45788888888888875 PP == domain 5 score: 4.3 bits; conditional E-value: 0.011 ETF_alpha 50 erqvGqtGktvaPklyiavGis 71 + v G t +P+l+i +G+ FUN_000587-T1 108 PNLVIDCGVTDRPNLVIDCGVT 129 4444444555555555555543 PP == domain 6 score: 3.3 bits; conditional E-value: 0.022 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGis 71 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 147 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGVT 177 5677888888888888999999999999985 PP == domain 7 score: 3.2 bits; conditional E-value: 0.023 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGi 70 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 159 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGV 188 457788888888888888999999999998 PP == domain 8 score: 5.6 bits; conditional E-value: 0.0043 ETF_alpha 45 gwlpkerqvGqtGktvaPklyiavGis 71 g++++++ v G t +P+l+i +G+ FUN_000587-T1 187 GVTDRSNLVIDCGVTDRPNLVIDCGVT 213 555555555555555555555555553 PP == domain 9 score: 0.8 bits; conditional E-value: 0.13 ETF_alpha 53 vGqtGktvaPklyiavGi 70 v G t +P+l+i +G+ FUN_000587-T1 243 VIDCGVTDRPNLVIDCGV 260 445577778888888887 PP == domain 10 score: 3.2 bits; conditional E-value: 0.025 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGi 70 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 243 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGV 272 457788888888888888889999999988 PP == domain 11 score: 3.4 bits; conditional E-value: 0.021 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGis 71 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 279 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGVT 309 5677888888888888999999999999985 PP == domain 12 score: 3.3 bits; conditional E-value: 0.022 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGi 70 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 291 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGV 320 457788888888888899999999999998 PP == domain 13 score: 3.3 bits; conditional E-value: 0.022 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGi 70 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 303 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGV 332 457788888888888888888999998888 PP == domain 14 score: 3.4 bits; conditional E-value: 0.021 ETF_alpha 41 avdagwlpkerqvGqtGktvaPklyiavGis 71 ++d g++++ + v G t +P+l+i +G+ FUN_000587-T1 315 VIDCGVTDRPNLVIDCGVTDRPNLVIDCGVT 345 4577888888888888999999999999985 PP == domain 15 score: 4.4 bits; conditional E-value: 0.01 ETF_alpha 47 lpkerqvGqtGktvaPklyiavGis 71 +++ + v G t +P+l+i +G+ FUN_000587-T1 333 TDRPNLVIDCGVTDRPNLVIDCGVT 357 4444555555555555555555553 PP >> Ig_SMCHD1_4th SMCHD1 Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.4 0.1 0.0057 29 34 65 .. 11 39 .. 6 42 .. 0.79 2 ! 5.2 0.1 0.0069 35 31 65 .. 32 63 .. 28 66 .. 0.77 3 ! 5.2 0.1 0.0067 34 31 65 .. 44 75 .. 39 78 .. 0.77 4 ! 4.9 0.1 0.0082 42 31 64 .. 56 86 .. 51 90 .. 0.74 5 ? 4.2 0.1 0.014 72 31 61 .. 68 95 .. 67 114 .. 0.59 6 ! 6.3 0.1 0.0031 16 31 56 .. 104 126 .. 88 138 .. 0.52 7 ! 7.8 0.1 0.0011 5.5 31 65 .. 128 159 .. 125 162 .. 0.84 8 ! 6.7 0.1 0.0024 12 31 65 .. 164 195 .. 152 198 .. 0.66 9 ! 6.8 0.5 0.0021 11 35 69 .. 204 235 .. 197 258 .. 0.56 10 ! 5.0 0.2 0.0078 40 31 65 .. 236 267 .. 232 270 .. 0.76 11 ! 8.1 0.2 0.00087 4.4 31 65 .. 260 291 .. 247 294 .. 0.76 12 ! 6.5 0.5 0.0026 13 31 59 .. 308 321 .. 282 342 .. 0.51 13 ! 5.0 0.1 0.0076 39 31 64 .. 320 350 .. 315 353 .. 0.79 14 ! 5.7 0.1 0.0049 25 32 65 .. 333 363 .. 331 379 .. 0.61 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.0057 Ig_SMCHD1_4th 34 qpklivrckvlgapelpvvavDcSntGagqLt 65 +p+l++ c v ++lp ++Dc t+ +L+ FUN_000587-T1 11 RPNLVIDCGV---TDLPNLVIDCGVTDRPNLV 39 6889999855...669999****999887776 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0069 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqLt 65 +t +p+l++ c v+ p+ ++Dc t+ +L+ FUN_000587-T1 32 VTDRPNLVIDCGVTDRPN---LVIDCGVTDRPNLV 63 788999999998877655...58899888877665 PP == domain 3 score: 5.2 bits; conditional E-value: 0.0067 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqLt 65 +t +p+l++ c v+ p+ ++Dc t+ +L+ FUN_000587-T1 44 VTDRPNLVIDCGVTDRPN---LVIDCGVTDRPNLV 75 788999999998877655...58899888877665 PP == domain 4 score: 4.9 bits; conditional E-value: 0.0082 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqL 64 +t +p+l++ c v+ p+ ++Dc t+ +L FUN_000587-T1 56 VTDRPNLVIDCGVTDRPN---LVIDCGVTDRPNL 86 788899999998877655...4888888876665 PP == domain 5 score: 4.2 bits; conditional E-value: 0.014 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGa 61 +t +p+l++ c v+ p+l a+Dc t FUN_000587-T1 68 VTDRPNLVIDCGVTDRPNL---AIDCGVTYR 95 5666777777766665444...566655543 PP == domain 6 score: 6.3 bits; conditional E-value: 0.0031 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDc 56 +t +p+l++ c v+ p+ ++Dc FUN_000587-T1 104 VTDRPNLVIDCGVTDRPN---LVIDC 126 444455555554444332...24455 PP == domain 7 score: 7.8 bits; conditional E-value: 0.0011 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqLt 65 +t +p+l++ c v ++lp ++Dc t+ +L+ FUN_000587-T1 128 VTDRPNLVIDCGV---TDLPNLVIDCGVTDRPNLV 159 7999******966...669999****999987776 PP == domain 8 score: 6.7 bits; conditional E-value: 0.0024 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqLt 65 +t +p+l++ c v+ p+ ++Dc t+ ++L+ FUN_000587-T1 164 VTDRPNLVIDCGVTDRPN---LVIDCGVTDRSNLV 195 667777777776666544...47777777776665 PP == domain 9 score: 6.8 bits; conditional E-value: 0.0021 Ig_SMCHD1_4th 35 pklivrckvlgapelpvvavDcSntGagqLtgkvi 69 p+l++ c v+ p+ ++Dc t+ +L+ + + FUN_000587-T1 204 PNLVIDCGVTDRPN---LVIDCGVTDRPNLVIDCV 235 55555555444333...355555555554444333 PP == domain 10 score: 5.0 bits; conditional E-value: 0.0078 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqLt 65 +t +p+l++ c v+ p+ ++Dc t+ +L+ FUN_000587-T1 236 VTDRPNLVIDCGVTDRPN---LVIDCGVTDRPNLV 267 788899999998877655...58899888877665 PP == domain 11 score: 8.1 bits; conditional E-value: 0.00087 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqLt 65 +t +p+l++ c v ++lp ++Dc t+ +L+ FUN_000587-T1 260 VTDRPNLVIDCGV---TDLPNLVIDCGVTDRPNLV 291 7888888888855...5688889999888877665 PP == domain 12 score: 6.5 bits; conditional E-value: 0.0026 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSnt 59 +t +p+l+ +Dc t FUN_000587-T1 308 VTDRPNLV---------------IDCGVT 321 23333333...............333333 PP == domain 13 score: 5.0 bits; conditional E-value: 0.0076 Ig_SMCHD1_4th 31 itaqpklivrckvlgapelpvvavDcSntGagqL 64 +t +p+l++ c v+ p+ ++Dc t+ +L FUN_000587-T1 320 VTDRPNLVIDCGVTDRPN---LVIDCGVTDRPNL 350 788999999998877665...5899998887666 PP == domain 14 score: 5.7 bits; conditional E-value: 0.0049 Ig_SMCHD1_4th 32 taqpklivrckvlgapelpvvavDcSntGagqLt 65 t +p+l++ c v+ p+ ++Dc t+ +L+ FUN_000587-T1 333 TDRPNLVIDCGVTDRPN---LVIDCGVTDRPNLV 363 56666666665555443...35666666555544 PP >> Drf_FH1 Formin Homology Region 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.0 0.00064 3.3 44 109 .. 43 107 .. 4 158 .. 0.41 2 ? 3.1 0.0 0.021 1.1e+02 30 94 .. 113 177 .. 99 190 .. 0.47 3 ! 5.9 0.0 0.0028 14 25 99 .. 204 277 .. 185 301 .. 0.53 4 ! 4.6 0.0 0.0074 38 31 98 .. 294 360 .. 280 377 .. 0.46 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00064 Drf_FH1 44 aipsppplpgataippppplpgaasippppplpgstdippppplpgsagipppppplpggagvppp 109 +++ p+l + p l + + p l + ++ p l ++g+ p l +gv FUN_000587-T1 43 GVTDRPNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCGVTDRPNLAIDCGV-TYRPNLVIDCGVTDR 107 22222222222222222222222222222333333333333333323222.112222222222211 PP == domain 2 score: 3.1 bits; conditional E-value: 0.021 Drf_FH1 30 gtssspppllpgsaaipsppplpgataippppplpgaasippppplpgstdippppplpgsagip 94 + + p l+ + +++ p+l + p l + + p l + ++ p l ++g+ FUN_000587-T1 113 DCGVTDRPNLVIDCGVTDRPNLVIDCGVTDLPNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCGVT 177 33334444444444444444444444444444444444444444444444444444444444443 PP == domain 3 score: 5.9 bits; conditional E-value: 0.0028 Drf_FH1 25 splpegtssspppllpgsaaipsppplpgataippppplpgaasippppplpgstdippppplpgsagipppppp 99 ++l + + p l+ + +++ p+l ++ p l + + p l + ++ p l ++g+ p FUN_000587-T1 204 PNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCVVTDRPNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCGVT-DLPN 277 3333444444555555555555555555555555555555555555555555555555555555555553.2223 PP == domain 4 score: 4.6 bits; conditional E-value: 0.0074 Drf_FH1 31 tssspppllpgsaaipsppplpgataippppplpgaasippppplpgstdippppplpgsagippppp 98 + + p l+ + +++ p+l + p l + + p l + ++ p l ++g+ p FUN_000587-T1 294 CGVTDRPNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCGVTDRPNLVIDCGVTD-RP 360 33344444444444444444444444444444444444444444444444444444444444422.22 PP >> BMF Bcl-2-modifying factor, apoptosis # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.019 96 94 117 .. 14 37 .. 6 42 .. 0.85 2 ? 1.5 0.1 0.045 2.3e+02 98 116 .. 42 60 .. 29 78 .. 0.55 3 ? 1.5 0.1 0.045 2.3e+02 97 118 .. 65 86 .. 54 110 .. 0.60 4 ? 0.1 0.0 0.12 6.1e+02 95 117 .. 99 121 .. 90 125 .. 0.74 5 ? 0.3 0.0 0.11 5.5e+02 94 116 .. 110 132 .. 102 136 .. 0.70 6 ? 3.3 0.2 0.013 65 95 117 .. 135 157 .. 126 184 .. 0.77 7 ? 2.2 0.1 0.026 1.3e+02 98 117 .. 186 205 .. 172 221 .. 0.60 8 ? 0.4 0.1 0.098 5e+02 94 116 .. 206 228 .. 198 235 .. 0.72 9 ? 1.3 0.0 0.053 2.7e+02 87 117 .. 235 265 .. 225 270 .. 0.81 10 ? 3.2 0.2 0.013 68 95 117 .. 267 289 .. 258 315 .. 0.78 11 ? 1.1 0.0 0.059 3e+02 93 116 .. 301 324 .. 285 329 .. 0.58 12 ? 0.2 0.1 0.11 5.8e+02 95 117 .. 315 337 .. 307 345 .. 0.79 13 ? 0.8 0.0 0.073 3.7e+02 98 117 .. 342 361 .. 333 374 .. 0.55 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.019 BMF 94 frapcgtgglvdltlgpGvreePr 117 + cg+ l +l++ +Gv++ P FUN_000587-T1 14 LVIDCGVTDLPNLVIDCGVTDRPN 37 5568*****************996 PP == domain 2 score: 1.5 bits; conditional E-value: 0.045 BMF 98 cgtgglvdltlgpGvreeP 116 cg+ +l++ +Gv++ P FUN_000587-T1 42 CGVTDRPNLVIDCGVTDRP 60 4444444444444444444 PP == domain 3 score: 1.5 bits; conditional E-value: 0.045 BMF 97 pcgtgglvdltlgpGvreePra 118 cg+ +l++ +Gv++ P FUN_000587-T1 65 DCGVTDRPNLVIDCGVTDRPNL 86 5566666666666666666543 PP == domain 4 score: 0.1 bits; conditional E-value: 0.12 BMF 95 rapcgtgglvdltlgpGvreePr 117 cg+ +l++ +Gv++ P FUN_000587-T1 99 VIDCGVTDRPNLVIDCGVTDRPN 121 45688888888888888888885 PP == domain 5 score: 0.3 bits; conditional E-value: 0.11 BMF 94 frapcgtgglvdltlgpGvreeP 116 + cg+ +l++ +Gv++ P FUN_000587-T1 110 LVIDCGVTDRPNLVIDCGVTDRP 132 45567888888888888888877 PP == domain 6 score: 3.3 bits; conditional E-value: 0.013 BMF 95 rapcgtgglvdltlgpGvreePr 117 cg+ l +l++ +Gv++ P FUN_000587-T1 135 VIDCGVTDLPNLVIDCGVTDRPN 157 56788888888888888888875 PP == domain 7 score: 2.2 bits; conditional E-value: 0.026 BMF 98 cgtgglvdltlgpGvreePr 117 cg+ +l++ +Gv++ P FUN_000587-T1 186 CGVTDRSNLVIDCGVTDRPN 205 55555555555555555553 PP == domain 8 score: 0.4 bits; conditional E-value: 0.098 BMF 94 frapcgtgglvdltlgpGvreeP 116 + cg+ +l++ +Gv++ P FUN_000587-T1 206 LVIDCGVTDRPNLVIDCGVTDRP 228 45568888888888888888887 PP == domain 9 score: 1.3 bits; conditional E-value: 0.053 BMF 87 vvsartafrapcgtgglvdltlgpGvreePr 117 vv+ r + cg+ +l++ +Gv++ P FUN_000587-T1 235 VVTDRPNLVIDCGVTDRPNLVIDCGVTDRPN 265 5666677778899999999999999999985 PP == domain 10 score: 3.2 bits; conditional E-value: 0.013 BMF 95 rapcgtgglvdltlgpGvreePr 117 cg+ l +l++ +Gv++ P FUN_000587-T1 267 VIDCGVTDLPNLVIDCGVTDRPN 289 56788888888888888888875 PP == domain 11 score: 1.1 bits; conditional E-value: 0.059 BMF 93 afrapcgtgglvdltlgpGvreeP 116 + cg+ +l++ +Gv++ P FUN_000587-T1 301 NLVIDCGVTDRPNLVIDCGVTDRP 324 334455555555666666666555 PP == domain 12 score: 0.2 bits; conditional E-value: 0.11 BMF 95 rapcgtgglvdltlgpGvreePr 117 cg+ +l++ +Gv++ P FUN_000587-T1 315 VIDCGVTDRPNLVIDCGVTDRPN 337 56788889999999999999885 PP == domain 13 score: 0.8 bits; conditional E-value: 0.073 BMF 98 cgtgglvdltlgpGvreePr 117 cg+ +l++ +Gv++ P FUN_000587-T1 342 CGVTDRPNLVIDCGVTDRPN 361 55555555555555555543 PP >> Glyphos_transf CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.38 1.9e+03 267 290 .. 15 38 .. 13 47 .. 0.87 2 ? -2.2 0.0 0.41 2.1e+03 277 290 .. 49 62 .. 30 82 .. 0.61 3 ? -2.1 0.0 0.39 2e+03 267 290 .. 135 158 .. 132 164 .. 0.88 4 ? 1.9 0.0 0.024 1.2e+02 267 290 .. 183 206 .. 176 213 .. 0.89 5 ? -0.3 0.0 0.11 5.6e+02 266 290 .. 230 254 .. 225 256 .. 0.90 6 ? -2.1 0.0 0.4 2e+03 267 290 .. 267 290 .. 265 296 .. 0.87 7 ? -2.6 0.0 0.57 2.9e+03 277 290 .. 325 338 .. 314 352 .. 0.53 8 ? -3.2 0.0 0.87 4.4e+03 267 290 .. 339 362 .. 332 367 .. 0.75 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.38 Glyphos_transf 267 asDiLiTDYSSvmFDyavldrPii 290 + D+ +TD +++D v+drP + FUN_000587-T1 15 VIDCGVTDLPNLVIDCGVTDRPNL 38 568889****************76 PP == domain 2 score: -2.2 bits; conditional E-value: 0.41 Glyphos_transf 277 SvmFDyavldrPii 290 +++D v+drP + FUN_000587-T1 49 NLVIDCGVTDRPNL 62 44444444444433 PP == domain 3 score: -2.1 bits; conditional E-value: 0.39 Glyphos_transf 267 asDiLiTDYSSvmFDyavldrPii 290 + D+ +TD +++D v+drP + FUN_000587-T1 135 VIDCGVTDLPNLVIDCGVTDRPNL 158 568889****************76 PP == domain 4 score: 1.9 bits; conditional E-value: 0.024 Glyphos_transf 267 asDiLiTDYSSvmFDyavldrPii 290 + D+ +TD S +++D v+drP + FUN_000587-T1 183 VIDCGVTDRSNLVIDCGVTDRPNL 206 66888*****************76 PP == domain 5 score: -0.3 bits; conditional E-value: 0.11 Glyphos_transf 266 lasDiLiTDYSSvmFDyavldrPii 290 l+ D+ +TD +++D v+drP + FUN_000587-T1 230 LVIDCVVTDRPNLVIDCGVTDRPNL 254 5679*******************66 PP == domain 6 score: -2.1 bits; conditional E-value: 0.4 Glyphos_transf 267 asDiLiTDYSSvmFDyavldrPii 290 + D+ +TD +++D v+drP + FUN_000587-T1 267 VIDCGVTDLPNLVIDCGVTDRPNL 290 568889****************76 PP == domain 7 score: -2.6 bits; conditional E-value: 0.57 Glyphos_transf 277 SvmFDyavldrPii 290 +++D v+drP + FUN_000587-T1 325 NLVIDCGVTDRPNL 338 55555555555533 PP == domain 8 score: -3.2 bits; conditional E-value: 0.87 Glyphos_transf 267 asDiLiTDYSSvmFDyavldrPii 290 + D+ +TD +++D v+drP + FUN_000587-T1 339 VIDCGVTDRPNLVIDCGVTDRPNL 362 456778888888888888888865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (386 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 74 (0.00289685); expected 510.9 (0.02) Passed bias filter: 46 (0.00180074); expected 510.9 (0.02) Passed Vit filter: 7 (0.000274026); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.38u 0.37s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 3825.12 // Query: FUN_000588-T1 [L=456] Description: FUN_000588 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-66 222.5 0.3 8e-66 222.1 0.3 1.1 1 YBD YAP binding domain 1.3e-27 96.3 0.1 2.7e-27 95.3 0.1 1.5 1 TEA TEA/ATTS domain Domain annotation for each model (and alignments): >> YBD YAP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 222.1 0.3 6.2e-70 8e-66 18 201 .] 266 453 .. 245 453 .. 0.91 Alignments for each domain: == domain 1 score: 222.1 bits; conditional E-value: 6.2e-70 YBD 18 ervdlvklsk...laDesleaidlsqiaekfPrv...lrelfekgpkdaffLvkvWadlnfdleddeskadalyavdslyeslekfdvevstkais 107 +++ +++l l D++lea+d+ qi++kfP++ l+el++kgp+ +ffLvk+Wadln +++d+ a+y+v+s yes e++++++s k++s FUN_000588-T1 266 HKHLFIHLGPntdLGDPHLEAVDIRQIYDKFPEKkggLKELYDKGPQAVFFLVKFWADLNTNIHDEAG---AFYGVSSTYESNENMTITCSSKVCS 358 45556666334559******************976669**************************9998...8************************ PP YBD 108 lgkqvvekievyepveedsrysfalessplCeymvkfiakLkklngidlmnkvLenftvlqvvrnretdevllslafvfevskepept.vrvyrL 201 +gkqvvek+e + +e++r+++++++sp+Ceym++f+ kLk+l ++ +mn+vLenft+lqvv nret+e+ll la+vfevs + +++ +++yrL FUN_000588-T1 359 FGKQVVEKVETEYGHYENNRFVYRIHRSPMCEYMINFVHKLKQLPEKYMMNSVLENFTILQVVSNRETQETLLCLAYVFEVSTSEHGAqHHIYRL 453 *************************************************************************************9999*****8 PP >> TEA TEA/ATTS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.3 0.1 2.1e-31 2.7e-27 2 66 .. 22 88 .. 21 90 .. 0.96 Alignments for each domain: == domain 1 score: 95.3 bits; conditional E-value: 2.1e-31 TEA 2 eavWpeeleaaflealrkyppsgrkklk..iegrfpgRnelIseyilektgkeRtrKQvsShiQvlk 66 e vW++++e+ f+eal++ypp+gr+k+ eg+++gRnelI++yi+ +tgk+RtrKQvsShiQvl FUN_000588-T1 22 EGVWSPDIEQSFQEALAIYPPCGRRKIIlsDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLA 88 78*************************99999*********************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (456 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1000 (0.0391466); expected 510.9 (0.02) Passed bias filter: 600 (0.023488); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4418.60 // Query: FUN_000589-T1 [L=292] Description: FUN_000589 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-36 124.5 0.0 7.2e-32 111.1 0.0 2.1 2 His_Phos_1 Histidine phosphatase superfamily (branch 1) Domain annotation for each model (and alignments): >> His_Phos_1 Histidine phosphatase superfamily (branch 1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 111.1 0.0 2.8e-36 7.2e-32 1 137 [. 43 179 .. 43 184 .. 0.91 2 ! 11.4 0.0 1e-05 0.26 139 172 .. 217 247 .. 205 270 .. 0.65 Alignments for each domain: == domain 1 score: 111.1 bits; conditional E-value: 2.8e-36 His_Phos_1 1 lyLvRHGetewnlegrlqgrtDvpLteeGreqaealaerlaevpidaiysSplkRarqTaeliaealg....lpvelderLrEidfGdweglttee 92 l LvRHGet n++ ++qg+ D+ L+eeG++qa ++ rl+++++++++sS+l Rar Tae+i + + ++v++d rL+E+ +G +eg ++++ FUN_000589-T1 43 LTLVRHGETPENKNDIFQGHLDTILSEEGIRQASLVGIRLKDEKFSHVFSSDLTRARMTAEAIVSRSNccsqIKVREDSRLKERGYGVIEGCSKAQ 138 68****************************************************************99**99********************7777 PP His_Phos_1 93 iaeeypeeleawladpadvrppggEsleevaaRveaaleelaarh 137 + ++ +p+++ p+g E+l+ev +Rv++++++++++ FUN_000589-T1 139 FFQM----AAKENVKPSNFVPEGAETLREVSQRVVECFNAIISEV 179 7666....555555666677889*****************99875 PP == domain 2 score: 11.4 bits; conditional E-value: 1e-05 His_Phos_1 139 getvlvVsHggvirallaall.glpleelrrleld 172 +++l+VsHggv+r l ++++ +l+ e ++++ FUN_000589-T1 217 IGNLLLVSHGGVLRQLFNHFFvELESE----FPVE 247 4679***************99333332....3333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (292 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 634 (0.0248189); expected 510.9 (0.02) Passed bias filter: 466 (0.0182423); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 3019.82 // Query: FUN_000591-T1 [L=242] Description: FUN_000591 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00019 21.8 0.0 0.00032 21.1 0.0 1.5 1 WH1 WH1 domain Domain annotation for each model (and alignments): >> WH1 WH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 1.2e-08 0.00032 59 110 .. 94 148 .. 31 149 .. 0.80 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 1.2e-08 WH1 59 akviieqeiyknleynqarqffhtfedsra...vvGLnFaseeeakkFakkvqea 110 + + +++++ +y +++ +fht s++ ++GL F +e+ a+ F+k+vq+a FUN_000591-T1 94 GFSTWKETLTSSSNYREQQRNFHTLMLSTGdgtMAGLRFNNEDAARVFLKEVQDA 148 556799******************987776667*******************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (242 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 742 (0.0290468); expected 510.9 (0.02) Passed bias filter: 603 (0.0236054); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2462.73 // Query: FUN_000592-T1 [L=291] Description: FUN_000592 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (291 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 631 (0.0247015); expected 510.9 (0.02) Passed bias filter: 474 (0.0185555); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2848.58 // Query: FUN_000593-T1 [L=888] Description: FUN_000593 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-08 33.9 9.6 8.9e-08 32.5 9.6 1.8 1 zf-RING_UBOX RING-type zinc-finger 4.5e-08 34.0 0.9 1.5e-07 32.3 0.1 2.4 1 Bcl-2 Apoptosis regulator proteins, Bcl-2 family 3.9e-06 27.1 12.7 1.1e-05 25.6 12.7 1.8 1 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 4.2e-06 27.4 12.6 1.2e-05 25.9 11.6 2.3 2 zf-RING_2 Ring finger domain 1.2e-05 25.5 12.0 3.1e-05 24.2 12.0 1.8 1 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 2.3e-05 24.8 11.0 5.9e-05 23.4 11.0 1.8 1 zf-RING_5 zinc-RING finger domain 6.3e-05 23.3 9.3 0.03 14.8 0.3 5.2 5 NHL NHL repeat 0.00028 21.1 10.7 0.00069 19.8 10.7 1.7 1 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 0.0012 18.9 0.1 0.0041 17.2 0.0 1.9 1 DUF7578 Domain of unknown function (DUF7578) 0.0036 17.1 0.0 0.29 10.8 0.0 2.3 2 DUF5711 Family of unknown function (DUF5711) 0.0058 17.2 12.9 0.013 16.1 12.9 1.6 1 zf-C3HC4_4 zinc finger of C3HC4-type, RING 0.0083 16.2 0.9 0.017 15.2 0.9 1.4 1 CENP-K Centromere-associated protein K ------ inclusion threshold ------ 0.042 14.2 0.4 0.91 9.9 0.2 2.5 2 CHASE3 CHASE3 domain 0.044 14.1 5.0 0.12 12.8 5.0 1.7 1 zf-RING_6 zf-RING of BARD1-type protein 0.075 13.8 2.3 0.24 12.2 2.3 1.9 1 HH_RND_rel RND related, alpha-helical hairpin domain 0.087 12.4 2.0 15 5.1 0.2 3.4 2 DUF5128 6-bladed beta-propeller 0.2 11.7 0.0 0.87 9.6 0.0 1.9 1 SGL SMP-30/Gluconolactonase/LRE-like region 0.31 11.7 2.7 0.43 11.2 0.8 2.2 1 TolA_bind_tri TolA binding protein trimerisation 0.33 11.7 1.2 4.5 8.0 0.2 2.8 2 DUF948 Bacterial protein of unknown function (DUF94 0.45 11.1 1.4 2 9.0 1.2 2.1 2 Fer2_4 2Fe-2S iron-sulfur cluster binding domain 0.54 10.8 10.8 2 9.0 10.8 2.0 1 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING 0.68 9.1 9.1 4.2 6.5 5.1 2.3 2 Tektin Tektin family 1.3 9.4 11.6 4.3 7.7 10.2 2.6 2 zf-RING_4 RING/Ubox like zinc-binding domain 1.4 9.3 7.5 3.8 7.9 7.5 1.7 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit 2.2 8.7 11.7 19 5.7 11.9 2.4 2 Prok-RING_4 Prokaryotic RING finger family 4 3.3 8.3 7.1 1.1 10.0 2.9 2.4 1 COG6_N Conserved oligomeric complex COG6, N-termina 4.9 7.9 5.4 7 7.4 3.3 2.3 2 GAT GAT domain 5.9 7.6 11.9 0.36 11.5 6.3 1.9 1 zf-RING_10 zinc RING finger of MSL2 6.4 7.5 13.2 17 6.1 13.2 1.8 1 Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING 8.6 7.2 10.1 0.71 10.6 4.3 2.1 1 Rab11-FIP3 Rab11-FIP3-like domain Domain annotation for each model (and alignments): >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 9.6 1e-10 8.9e-08 1 39 [] 362 401 .. 362 401 .. 0.93 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 1e-10 zf-RING_UBOX 1 CpICleeftdP.lvl.pCGHtfCreClwelskkekgkikCP 39 Cp+Cl+ef++P l +C H+ C+ Cl+++ +k + +i+CP FUN_000593-T1 362 CPVCLDEFKEPkC-LpSCAHNVCERCLENMVRKGSYTISCP 401 ***********54.549***********************9 PP >> Bcl-2 Apoptosis regulator proteins, Bcl-2 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.3 0.1 1.8e-10 1.5e-07 1 100 [] 190 287 .. 186 287 .. 0.83 Alignments for each domain: == domain 1 score: 32.3 bits; conditional E-value: 1.8e-10 Bcl-2 1 Lrrlgdeleekheeelesmleqlelteetarelfrevaeelfs.dgeinWgrvvalfafagalavklvrqgqeelveklaewlaeyleeeladWir 95 L+++ +e++++ ++++++ l+ + + +e f+ a++l ++ + W++v+ l++fa ++a+ + +++e+lae ++++e+ ++Wi+ FUN_000593-T1 190 LEKISQEIMQMIPDLMDEPLKIMRG-GNLSYEQFSVAARRLTFdHQIVGWSKVALLCHFAREVAITGELD--DSQLEMLAEHSFRFIQESTEEWIE 282 5667777777777777777777555.5778888998888876626799*****************95544..6679******************** PP Bcl-2 96 eqgGW 100 ++gGW FUN_000593-T1 283 KKGGW 287 ***** PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 12.7 1.3e-08 1.1e-05 1 40 [] 362 403 .. 362 403 .. 0.90 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 1.3e-08 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCikslle..snnvkCplC 40 Cp+Cl+e+kep+ l C H C+ C++++++ s + Cp C FUN_000593-T1 362 CPVCLDEFKEPKCLPSCAHNVCERCLENMVRkgSYTISCPQC 403 ************9999***************5444445**** PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 11.6 1.5e-08 1.2e-05 2 44 .] 361 404 .. 360 404 .. 0.89 2 ? -1.9 0.0 7 6e+03 10 27 .. 685 704 .. 684 705 .. 0.70 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 1.5e-08 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst...CPlCr 44 +Cp+Cl+e++e++++ C H ++ Cl++++r+ s CP Cr FUN_000593-T1 361 SCPVCLDEFKEPKCLP--SCAHNVCERCLENMVRKGSYtisCPQCR 404 8********8777766..4************99998889******9 PP == domain 2 score: -1.9 bits; conditional E-value: 7 zf-RING_2 10 leeeekvivl..pCgHvfhk 27 +++++++ivl +C+ +h+ FUN_000593-T1 685 FSKDDEIIVLsrECNRLLHY 704 6677887766336*999997 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 12.0 3.7e-08 3.1e-05 2 40 .] 362 403 .. 361 403 .. 0.96 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 3.7e-08 zf-C3HC4_2 2 CpiCldmlkdplvvtpCgHvfCqkCilraLeesn...eCPlC 40 Cp+Cld++k+p + C H C+ C+ + ++++ +CP+C FUN_000593-T1 362 CPVCLDEFKEPKCLPSCAHNVCERCLENMVRKGSytiSCPQC 403 ***********9999*****************988889**** PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 11.0 6.9e-08 5.9e-05 2 42 .. 362 404 .. 361 405 .. 0.96 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 6.9e-08 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll....eerqCpiCk 42 C++C +e+ +++ +l sC H +Ce+Cl ++ +Cp+C+ FUN_000593-T1 362 CPVCLDEF--KEPKCLPSCAHNVCERCLENMVrkgsYTISCPQCR 404 ********..**********************9999999*****8 PP >> NHL NHL repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 1.7 1.4e+03 4 16 .. 411 423 .. 408 424 .. 0.90 2 ? -0.8 0.0 3.1 2.7e+03 8 25 .. 641 659 .. 640 662 .. 0.78 3 ? 1.6 0.0 0.57 4.9e+02 5 18 .. 681 694 .. 678 704 .. 0.82 4 ! 7.2 0.5 0.0094 8 1 28 [] 774 800 .. 774 800 .. 0.93 5 ! 14.8 0.3 3.5e-05 0.03 2 28 .] 816 843 .. 815 843 .. 0.91 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1.7 NHL 4 PhGvavdsdGdiy 16 P+Gv+ +++++++ FUN_000593-T1 411 PTGVSSFPTNHLL 423 9*********996 PP == domain 2 score: -0.8 bits; conditional E-value: 3.1 NHL 8 avd.sdGdiyVaDsenhrv 25 av+ +Gdi D e rv FUN_000593-T1 641 AVSnVSGDIALLDEEDRRV 659 566699*******998777 PP == domain 3 score: 1.6 bits; conditional E-value: 0.57 NHL 5 hGvavdsdGdiyVa 18 ++v+ ++d++i+V FUN_000593-T1 681 WDVTFSKDDEIIVL 694 99**********96 PP == domain 4 score: 7.2 bits; conditional E-value: 0.0094 NHL 1 fnrPhGvavdsdGdiyVaDsenhrvqvF 28 + +P++v+ +G ++V+D + +vqvF FUN_000593-T1 774 LHCPQDVVFH-QGKFFVTDGDLECVQVF 800 679******7.*********99999999 PP == domain 5 score: 14.8 bits; conditional E-value: 3.5e-05 NHL 2 nrPhGvavd.sdGdiyVaDsenhrvqvF 28 +P Gv+vd ++ ++++Ds ++ ++vF FUN_000593-T1 816 LDPIGVTVDpMNNVVLICDSSSNAIVVF 843 68*******8889999999********9 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 10.7 8.1e-07 0.00069 2 45 .. 359 406 .. 358 407 .. 0.92 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 8.1e-07 zf-C3HC4_3 2 eeeCviClerernvvllp.CgHlclCeeCaeklr....kkkkCpiCrqk 45 e+ C +Cl++ ++ +lp C H +Ce C e++ + +Cp Cr++ FUN_000593-T1 359 ETSCPVCLDEFKEPKCLPsCAHN-VCERCLENMVrkgsYTISCPQCREE 406 789**********999988****.**********9999999******86 PP >> DUF7578 Domain of unknown function (DUF7578) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 4.9e-06 0.0041 6 43 .. 499 534 .. 498 539 .. 0.90 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 4.9e-06 DUF7578 6 kLnDFLrselggrgvvdenenVsmevFvkePeryiqDe 43 +L DFL ++++++ v +++Vsm+ ++e ++y + + FUN_000593-T1 499 RLDDFLAEHFDENSVE--KQQVSMRSYLREAKTYLHGA 534 799**********887..59**************9876 PP >> DUF5711 Family of unknown function (DUF5711) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.051 43 68 157 .. 649 739 .. 636 741 .. 0.82 2 ! 10.8 0.0 0.00035 0.29 109 159 .. 830 876 .. 821 885 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.051 DUF5711 68 vaiaDkggnkiyvfdkk..gllgeietsl.pIekvsvssqGvvaavledeestyIelYdkeGeelaeikttmeksGYpldialSpdgkklavs 157 +a D++ +++y+f+++ ++++e+ +++ + +v+ s+ ++++ e +++ Yd+eG+ + ++ t + + ++ i+ dg+ l++s FUN_000593-T1 649 IALLDEEDRRVYIFNNSfgDIVSEFCVNYdDLWDVTFSKDDEIIVLSR--ECNRLLHYDREGTFIKKHVKTPNAQVKFTRISTDADGRFLITS 739 7889999*********99889999999994599********9999987..5569999*****9995555555777788888888888888887 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00035 DUF5711 109 avledeestyIelYdkeGeelaeikttmeksGYpldialSpdgkklavsyl 159 +++ d++s+ I +++ +Ge ++ei+t+ +pl +alS +++ l+v + FUN_000593-T1 830 VLICDSSSNAIVVFKPNGELVSEIETS----EEPLHVALSLNARSLIVCFH 876 555678889999999999999999995....99999999999999999875 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 12.9 1.5e-05 0.013 1 42 [] 362 403 .. 362 403 .. 0.95 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 1.5e-05 zf-C3HC4_4 1 CpvCldyLekPvsie.CGhsfClsCisslqkepdgesllCplC 42 CpvCld +++P ++ C h++C +C+ ++ ++ + +Cp+C FUN_000593-T1 362 CPVCLDEFKEPKCLPsCAHNVCERCLENMVRKGSYT-ISCPQC 403 **************66**************999886.****** PP >> CENP-K Centromere-associated protein K # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.9 2e-05 0.017 106 190 .. 436 519 .. 396 540 .. 0.68 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2e-05 CENP-K 106 nkklkedLerEqewldeqqeilesLksktkelknqvvtlsekrkfael.keklrkikeykekllttLgefleehfplpeeedaevk 190 +k+l e L+ e ++ ++ l+ +++ +++ nq ++ + +++l ++ +++i ++++ ll+ L++fl ehf + e+++v FUN_000593-T1 436 KKELTEALNVCYERVKAAENALQEMEECYENATNQTDKIRGE--INKLaDDLIQTISKQRNSLLSRLDDFLAEHFDENSVEKQQVS 519 455777777777777777776666666666666666655433..4444146788999******************97775555554 PP >> CHASE3 CHASE3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.41 3.5e+02 68 106 .. 186 225 .. 179 231 .. 0.83 2 ? 9.9 0.2 0.0011 0.91 2 54 .. 465 517 .. 464 567 .. 0.88 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.41 CHASE3 68 qqerlerlealieqkl.eeaeetialrreggleaaaalvr 106 ++rle++++ i q + ++++e ++ +r g+l ++ +v+ FUN_000593-T1 186 VAARLEKISQEIMQMIpDLMDEPLKIMRGGNLSYEQFSVA 225 5789**********************99877766665555 PP == domain 2 score: 9.9 bits; conditional E-value: 0.0011 CHASE3 2 aewvehtqevlaaleqllaalvdaEtgqRGYlltgdesfLepyeearaeieel 54 ++ +++t +++ ++++l +l ++ + qR ll++ ++fL+++ + ++ +++ FUN_000593-T1 465 ENATNQTDKIRGEINKLADDLIQTISKQRNSLLSRLDDFLAEHFDENSVEKQQ 517 57899*************************************99887666555 PP >> zf-RING_6 zf-RING of BARD1-type protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 5.0 0.00014 0.12 9 46 .. 361 403 .. 356 410 .. 0.79 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00014 zf-RING_6 9 rcsrctdilrepvclggcehifcsncisdcfgsg.....cpvc 46 c c d ++ep cl c h c c+ + g cp c FUN_000593-T1 361 SCPVCLDEFKEPKCLPSCAHNVCERCLENMVRKGsytisCPQC 403 5999***********************9876444222226666 PP >> HH_RND_rel RND related, alpha-helical hairpin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 2.3 0.00028 0.24 17 74 .. 456 513 .. 436 525 .. 0.81 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00028 HH_RND_rel 17 elknkekeeelfekdiekldeeIdklikeiqkkikegdyekieelKeeLssllekkki 74 +l++ e+ e+ +++ +k+ eI+kl +++ + i++++ + +++l + L + ++++++ FUN_000593-T1 456 ALQEMEECYENATNQTDKIRGEINKLADDLIQTISKQRNSLLSRLDDFLAEHFDENSV 513 3455566778899999******************************999999998776 PP >> DUF5128 6-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.14 1.2e+02 97 125 .. 686 712 .. 640 731 .. 0.70 2 ? 5.1 0.2 0.017 15 47 117 .. 779 844 .. 773 854 .. 0.60 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.14 DUF5128 97 dksnesIyildfmkkKiltYdLdgysfle 125 ++++I++l + +++l Yd +g f++ FUN_000593-T1 686 S-KDDEIIVLSRECNRLLHYDREG-TFIK 712 4.4557778888888888888877.6654 PP == domain 2 score: 5.1 bits; conditional E-value: 0.017 DUF5128 47 rikvvddrifvlDsaknnlfvFdkkGkfirkIgaqGnGPgEYlqlndfiidksnesIyildfmkkKiltYd 117 + +++++ fv+D + + vF+ Gkf ++ g++ l + ++d n+ + i d+ ++i+++ FUN_000593-T1 779 DVVFHQGKFFVTDGDLECVQVFNSWGKFLFEFGSR-----VLLDPIGVTVDPMNNVVLICDSSSNAIVVFK 844 57778888888888888888888888887776554.....3445555555555555555555555555554 PP >> SGL SMP-30/Gluconolactonase/LRE-like region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.0 0.001 0.87 52 225 .. 689 857 .. 675 873 .. 0.69 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.001 SGL 52 gglivalksgvalldldsgeltkladseedekpenrfNDgkvdpdGrlwaGtmaddeakgkee...galyrldpdgk..lerlldgltisNGlaws 142 +++iv +++ ll+ ++e t + ++++ ++++f d+dGr+ +++ d +++ ee ++++++ d k + +d+l+++ + + FUN_000593-T1 689 DEIIVLSRECNRLLH-YDREGTFIKKHVKTPNAQVKFTRISTDADGRFLITSSPRDCCDDPEElvePCVLVYSSDRKfiFSFGVDRLHCPQDVVFH 783 455555555445554.33455666666666667777777788888888888887777777777777555555555443366667888888877776 PP SGL 143 pDgktlYlaDslarkiyafdydaeggelsnrrvfadfkkge.gepDGlavDa.eGgvwvAlwgggkvvrfdpdGklleeielPak 225 + +++++D +++++f+ g + +++f + p G++vD ++ v ++ +++ +v+f+p+G+l+ eie+ + FUN_000593-T1 784 Q--GKFFVTDGDLECVQVFNSW---G----K-FLFEFGSRVlLDPIGVTVDPmNNVVLICDSSSNAIVVFKPNGELVSEIETS-E 857 4..5677888888888888772...2....2.23455555434577******8899999*********************987.3 PP >> TolA_bind_tri TolA binding protein trimerisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.8 0.0005 0.43 14 66 .. 451 504 .. 447 511 .. 0.79 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0005 TolA_bind_tri 14 earnqallelqqqleqLqqevaeLRGqiEelqyqleqlqeRqrd.lYldlDqrl 66 +a ++al e+ + e+ ++ +++RG+i +l+ +l q+ +qr+ l lD l FUN_000593-T1 451 KAAENALQEMEECYENATNQTDKIRGEINKLADDLIQTISKQRNsLLSRLDDFL 504 344689999*************************98777777641666666655 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.2 0.0053 4.5 26 67 .. 448 489 .. 439 506 .. 0.84 2 ? 1.2 0.1 0.69 5.8e+02 34 62 .. 512 540 .. 507 578 .. 0.78 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0053 DUF948 26 ktldevnktleklekqldpllkettellaktnelledvnekl 67 + ++++++ l+++e+ ++ +++t+++ ++n+l++d+ + + FUN_000593-T1 448 ERVKAAENALQEMEECYENATNQTDKIRGEINKLADDLIQTI 489 568899999999999999999999999999999999986654 PP == domain 2 score: 1.2 bits; conditional E-value: 0.69 DUF948 34 tleklekqldpllkettellaktnelled 62 ++ek + + +l+e+++ l+ +ne+l++ FUN_000593-T1 512 SVEKQQVSMRSYLREAKTYLHGANEILQQ 540 67777888999999999999999998875 PP >> Fer2_4 2Fe-2S iron-sulfur cluster binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 1.2 0.0023 2 24 73 .. 332 384 .. 330 387 .. 0.90 2 ? -1.1 0.0 3.4 2.9e+03 3 16 .. 559 572 .. 558 573 .. 0.85 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0023 Fer2_4 24 AllangvrvprsckygrpRgilcaigeCrnClVeve..gepnv.raCttpvee 73 A++a g+ v+ s ++ ++i+ +g ++ C V ++ +ep+ +C v e FUN_000593-T1 332 AAAAIGIGVCISLVRHELKKIVNIMGDETSCPVCLDefKEPKClPSCAHNVCE 384 89999*****999999********************88899955***998876 PP == domain 2 score: -1.1 bits; conditional E-value: 3.4 Fer2_4 3 evtltiDGrevtap 16 e++ t+DGr+++a+ FUN_000593-T1 559 EISSTVDGRTLEAK 572 7899*******996 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 10.8 0.0024 2 2 54 .. 362 406 .. 361 408 .. 0.83 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0024 RING_XB3-XBAT31 2 CsiCferactieve.eCgHqlCaqCalalcskkkkteaataskespaCPfCRss 54 C +C++++ ++ +C H+ C +C +++ k + ++ CP CR++ FUN_000593-T1 362 CPVCLDEFKEPKCLpSCAHNVCERCLENMVRKGS---------YTISCPQCREE 406 9*********997527**********99988863.........34679999975 PP >> Tektin Tektin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.1 0.028 24 184 241 .. 90 147 .. 78 150 .. 0.83 2 ? 6.5 5.1 0.005 4.2 7 102 .. 441 539 .. 436 542 .. 0.86 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.028 Tektin 184 sykpgvtrvpkssstpeeWeeftqeniekaekeraasakLreaidsileqtandlraq 241 s ++v r+ ksss ++e+ q+ +++a+ +r+ s +L+++i++ +t + +q FUN_000593-T1 90 SSFKSVGRLSKSSSDAGSYEHKRQKFLRMAKLQRKLSLNLKNDIENFDPKTLRHRSKQ 147 556788999***********************************99877666655555 PP == domain 2 score: 6.5 bits; conditional E-value: 0.005 Tektin 7 ellkeaeaeraeaerlrqesrrlrneteektkkdqedsnkklgeRikdiefwkeelekeleelkeEi...elLeeekkrlekalealeeplsiaqe 99 e l+ + ++ + ae+ qe+++++++++++t+k + nk ++ i+ i++ ++ l l++ +E ++ e+++ ++ l + + l+ a+e FUN_000593-T1 441 EALNVCYERVKAAENALQEMEECYENATNQTDKIRGEINKLADDLIQTISKQRNSLLSRLDDFLAEHfdeNSVEKQQVSMRSYLREAKTYLHGANE 536 567778889999***************************************************998533377888888888888888888888888 PP Tektin 100 cle 102 l+ FUN_000593-T1 537 ILQ 539 776 PP >> zf-RING_4 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 1.5 1.3e+03 36 47 .. 358 369 .. 349 370 .. 0.73 2 ? 7.7 10.2 0.005 4.3 15 46 .. 374 406 .. 362 407 .. 0.75 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.5 zf-RING_4 36 eegrCPgCreeY 47 e CP C +e+ FUN_000593-T1 358 DETSCPVCLDEF 369 5789****8877 PP == domain 2 score: 7.7 bits; conditional E-value: 0.005 zf-RING_4 15 llPCeCgyqiClfCyedile..eeegrCPgCree 46 lP +C +++C C e++++ + + CP Cree FUN_000593-T1 374 CLP-SCAHNVCERCLENMVRkgSYTISCPQCREE 406 444.7**************94446889*****96 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 7.5 0.0044 3.8 11 56 .. 359 403 .. 353 404 .. 0.91 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0044 zf-Nse 11 slkcPltlqpfkePvtskkCnHvfekeaIlell.krkkkvkCPvvgC 56 + cP+ l +fkeP C H ++ +++++ k + ++ CP+ C FUN_000593-T1 359 ETSCPVCLDEFKEPKCLPSCAHNVCERCLENMVrKGSYTISCPQ--C 403 568******************************6667799****..8 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.2 0.42 3.6e+02 31 39 .. 360 368 .. 357 373 .. 0.76 2 ? 5.7 11.9 0.023 19 1 39 [. 362 406 .. 362 408 .. 0.72 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.42 Prok-RING_4 31 saCPiCrrr 39 +CP+C + FUN_000593-T1 360 TSCPVCLDE 368 57****865 PP == domain 2 score: 5.7 bits; conditional E-value: 0.023 Prok-RING_4 1 Cvlcgre.etkivlspCgHlvCkeCfdss....dfs.aCPiCrrr 39 C +c e ++ l +C+H vC+ C ++ + +CP Cr++ FUN_000593-T1 362 CPVCLDEfKEPKCLPSCAHNVCERCLENMvrkgSYTiSCPQCREE 406 7788877455678999*********9864222244469****975 PP >> COG6_N Conserved oligomeric complex COG6, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 2.9 0.0012 1.1 33 97 .. 434 499 .. 426 516 .. 0.79 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0012 COG6_N 33 kefgpvaeqLkrieedveklnesceemkkkleaakeetselleeassLkeekekielkq.kllkaf 97 ke ++++e+L+ e v++ +++ +em++ e+a+++t+++ e+++L +++ ++ +kq + l + FUN_000593-T1 434 KEKKELTEALNVCYERVKAAENALQEMEECYENATNQTDKIRGEINKLADDLIQTISKQrNSLLSR 499 6778999999**************************************999866555540444444 PP >> GAT GAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 4.9 4.2e+03 30 50 .. 187 207 .. 185 209 .. 0.84 2 ? 7.4 3.3 0.0083 7 6 71 .. 422 492 .. 420 498 .. 0.79 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 4.9 GAT 30 yercksaqpkiqklieetsde 50 + r++++++ i+++i + de FUN_000593-T1 187 AARLEKISQEIMQMIPDLMDE 207 68999**********987665 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0083 GAT 6 lLnemLsstnpe.eelldnelikeLyercksaqpkiqklieet....sdeed.llaellqlNDelnqvlekY 71 lL ++++t+ e+ + e+++ yer+k+a++ +q++ e + +++ d +e+ +l D+l q+++k FUN_000593-T1 422 LLLRLIENTPARkEKKELTEALNVCYERVKAAENALQEMEECYenatNQT-DkIRGEINKLADDLIQTISKQ 492 7888889988666666667777778*****************96654333.24889999999***9999986 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 6.3 0.00042 0.36 2 45 .. 361 405 .. 360 426 .. 0.81 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00042 zf-RING_10 2 sCvvCgkLLvdPltpkeseCqHyvCrlCvgk...kkklkpsCskCkd 45 sC vC ++P ++C H+vC +C+ + k + + sC++C++ FUN_000593-T1 361 SCPVCLDEFKEPKCL--PSCAHNVCERCLENmvrKGSYTISCPQCRE 405 899**9999999754..89*********8762215567789999984 PP >> Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 13.2 0.02 17 1 35 [] 362 403 .. 362 403 .. 0.84 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.02 Sina_RING 1 CpvCleymkppIlqCenGHliCssCrpkltk.......CptC 35 CpvCl+ +k p + H++C++C +++ + Cp+C FUN_000593-T1 362 CPVCLDEFKEPKCLPSCAHNVCERCLENMVRkgsytisCPQC 403 ***************************984334444558888 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 4.3 0.00084 0.71 47 101 .. 434 488 .. 428 501 .. 0.85 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00084 Rab11-FIP3 47 rleRekelelenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleel 101 + ++e + l+ + +R++++e+ +e++++ ++ +q+++++ e +kl d+l ++ FUN_000593-T1 434 KEKKELTEALNVCYERVKAAENALQEMEECYENATNQTDKIRGEINKLADDLIQT 488 5567777889999***********************************9987654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (888 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1614 (0.0631826); expected 510.9 (0.02) Passed bias filter: 1039 (0.0406733); expected 510.9 (0.02) Passed Vit filter: 157 (0.00614602); expected 25.5 (0.001) Passed Fwd filter: 32 (0.00125269); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 30 [number of targets reported over threshold] # CPU time: 0.47u 0.41s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 8313.76 // Query: FUN_000594-T1 [L=250] Description: FUN_000594 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.05 14.6 0.1 0.11 13.6 0.0 1.6 2 Bcl-2 Apoptosis regulator proteins, Bcl-2 family Domain annotation for each model (and alignments): >> Bcl-2 Apoptosis regulator proteins, Bcl-2 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 0.81 2.1e+04 34 42 .. 25 33 .. 11 39 .. 0.48 2 ? 13.6 0.0 4.1e-06 0.11 1 99 [. 107 204 .. 100 204 .. 0.80 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 0.81 Bcl-2 34 frevaeelf 42 +++ a elf FUN_000594-T1 25 IERQASELF 33 222222222 PP == domain 2 score: 13.6 bits; conditional E-value: 4.1e-06 Bcl-2 1 Lrrlgdeleekheeelesmleqlel..teetarelfrevaeelfs..dgeinWgrvvalfafagalavklvrqgqeelveklaewlaeyleeelad 92 ++++gd l + ++ ++e + l e++a+ ++ + ++e+ s + +W+ +++++++ ++av+ v+ + +++e +++y+ ++ ++ FUN_000594-T1 107 MQQAGDALCKTYKGRFEGNKNCLVNfvLENAASLTYDRLCTEIDSvvGRDRSWSNFAMVMCLGKRVAVETVNV-----CGSVSEHFSRYIGRSYGP 197 567777777777777776655543354256777778888888888753368******************8855.....****************** PP Bcl-2 93 WireqgG 99 ir+ gG FUN_000594-T1 198 SIRQAGG 204 ****999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (250 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 750 (0.02936); expected 510.9 (0.02) Passed bias filter: 662 (0.0259151); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2422.37 // Query: FUN_000595-T1 [L=321] Description: FUN_000595 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-68 227.6 3.3 1.3e-23 83.0 0.0 3.9 3 Mito_carr Mitochondrial carrier protein Domain annotation for each model (and alignments): >> Mito_carr Mitochondrial carrier protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.0 0.0 5e-28 1.3e-23 3 94 .. 5 97 .. 3 99 .. 0.95 2 ! 58.5 0.3 2.3e-20 5.8e-16 3 89 .. 102 216 .. 100 222 .. 0.89 3 ! 82.4 0.2 8.1e-28 2.1e-23 4 85 .. 226 308 .. 223 312 .. 0.94 Alignments for each domain: == domain 1 score: 83.0 bits; conditional E-value: 5e-28 Mito_carr 3 lsflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk.ildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklllk 94 sf a+l+ G+iag++++++t+Pld++Ktrlq q++ + k+++ ++d++ k++k eG rglykG+++nll + p++aik+a+ +++++++ + FUN_000595-T1 5 RSFSAKLINGAIAGVVGVSCTFPLDLAKTRLQDQRNLGPRKQYRnLMDCLWKVAKAEGARGLYKGIGVNLLLINPEKAIKLAVNDQVRQMYGG 97 68999********************************99988889********************************************9876 PP == domain 2 score: 58.5 bits; conditional E-value: 2.3e-20 Mito_carr 3 lsflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk............................ildafkkivkeeGirglykGllpn 70 l++ ++++aGg+ag++++++t+P++++K++lq++++++ + + ++++ +++++G+rglykGl+++ FUN_000595-T1 102 LPLSKEMIAGGAAGFCQVIITTPMEMLKIQLQMAGTQNLADSPMtpntttavaaassnvrtfgtksgtlpksAAEIAQDVLRSKGVRGLYKGLGAT 197 678899***************************88887665544677788888889999999999999**************************** PP Mito_carr 71 llrvapaaaikfatyetlk 89 l+r++p+++i+f ++ +l+ FUN_000595-T1 198 LARDVPFSCIYFPLFSFLR 216 ************9998876 PP == domain 3 score: 82.4 bits; conditional E-value: 8.1e-28 Mito_carr 4 sflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk.ildafkkivkeeGirglykGllpnllrvapaaaikfaty 85 s+ +sllaG++ag+i++l+++P+dvvKtrlq+ ++ + + ++ i+d+++k++++eGi+++ykG +p+++ +ap +i ++y FUN_000595-T1 226 SPSHSLLAGCVAGMIGSLAVTPMDVVKTRLQVLRNAQGEAAYSgIVDCVQKTYTNEGIMAFYKGAVPRMIVIAPLFGIAQMVY 308 67899***************************999998888889*********************************999988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 615 (0.0240752); expected 510.9 (0.02) Passed bias filter: 522 (0.0204345); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3212.07 // Query: FUN_000596-T1 [L=226] Description: FUN_000596 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-71 239.1 13.7 4.5e-71 238.9 13.7 1.1 1 vATP-synt_E ATP synthase (E/31 kDa) subunit ------ inclusion threshold ------ 2 8.9 7.6 3.7 8.0 7.6 1.5 1 PCF11_charged PCF11, charged region 4.8 6.6 11.8 12 5.3 10.6 2.0 2 Tox-ODYAM1 Toxin in Odyssella and Amoebophilus Domain annotation for each model (and alignments): >> vATP-synt_E ATP synthase (E/31 kDa) subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 238.9 13.7 5.3e-75 4.5e-71 1 199 [] 18 216 .. 18 216 .. 0.99 Alignments for each domain: == domain 1 score: 238.9 bits; conditional E-value: 5.3e-75 vATP-synt_E 1 fIkqeAeekAeeIkakaeeefeiekaklvqeaeekieeayekkeKqaelqkkiaiSnaknkarlkvLkareevleevfeeaekkLaeleedkdeYk 96 fI+qeA+ek++eI+akaeeef+iek++lvq+++ ki++ +ekkeKq+elqkki+ Sn++n+a lk L+a++++++ +++ea k+L e+++d+ +Y+ FUN_000596-T1 18 FIEQEAKEKVDEIDAKAEEEFNIEKGRLVQQERLKIMNFFEKKEKQVELQKKIQRSNQLNQATLKKLRAQDDHIKGILDEAVKRLGEVTKDTPRYE 113 8*********************************************************************************************** PP vATP-synt_E 97 ellkkLivqalvkleepevivrarkeDeelveealdkaaeeykaktkkktvekageeedfl.edvlGGvvleaadgkikvnnTlearLelvaeqll 191 ++lk+Li q+l++l ep v+vr+r++D +lv++++ +a+e+yk++tkk +e ++e++fl d++GG++l a++g+ikv nTle+rLe++++q++ FUN_000596-T1 114 QVLKGLITQGLFQLLEPAVTVRCRQQDLSLVKKVKVAAIEDYKNATKKT-TEITVDEQSFLpSDCAGGIELLAKQGRIKVVNTLESRLEMMSRQMM 208 ********************************************99988.99999999**9999******************************** PP vATP-synt_E 192 peirkaLF 199 peir+ LF FUN_000596-T1 209 PEIRETLF 216 *******9 PP >> PCF11_charged PCF11, charged region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 7.6 0.00044 3.7 65 136 .. 5 75 .. 1 92 [. 0.74 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00044 PCF11_charged 65 DPRLrkhlqdKtdkkddevkeKkrssekkereeaakgsehrsagsrnklvNGsvnkhereeevekqekkvar 136 D rk+++ ++ ++e+keK ++ k +ee + + + ++++r k++N +k+e++ e++k+ +++++ FUN_000596-T1 5 DAEVRKQIEHMMQFIEQEAKEKVDEIDAKAEEEFNIEKGRLVQQERLKIMN-FFEKKEKQVELQKKIQRSNQ 75 67789***************************965555545667999**99.56777777666665333322 PP >> Tox-ODYAM1 Toxin in Odyssella and Amoebophilus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 10.6 0.0014 12 105 184 .. 7 86 .. 2 96 .. 0.86 2 ? -0.0 0.0 0.057 4.8e+02 220 239 .. 101 120 .. 92 125 .. 0.81 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0014 Tox-ODYAM1 105 evlkldrgrlernyeerrkevttsyqkkeeelekkkedisaklkvakhlrvelkkkeddlvkqleeeeelykvalkrlan 184 ev k + ++ +e +++v k eee++++k+++ ++ ++ e k+k+ +l k+++ +++l +++lk+l + FUN_000596-T1 7 EVRKQIEHMMQFIEQEAKEKVDEIDAKAEEEFNIEKGRLVQQERLKIMNFFEKKEKQVELQKKIQRSNQLNQATLKKLRA 86 56555666667777899999999999************9999888888789*************************9975 PP == domain 2 score: -0.0 bits; conditional E-value: 0.057 Tox-ODYAM1 220 alGtvarkkeayeqilkGst 239 lG v + yeq+lkG FUN_000596-T1 101 RLGEVTKDTPRYEQVLKGLI 120 49***************975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (226 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2684 (0.105069); expected 510.9 (0.02) Passed bias filter: 722 (0.0282638); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2198.07 // Query: FUN_000597-T1 [L=269] Description: FUN_000597 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-10 39.6 0.0 4.6e-05 23.9 0.0 3.1 3 DUF4537 Domain of unknown function (DUF4537) 1.3e-07 31.7 0.1 1.4 9.2 0.0 4.2 4 Tudor_5 Histone methyltransferase Tudor domain 1 2.2e-06 27.9 0.6 0.21 12.0 0.0 4.1 5 Tudor_3 DNA repair protein Crb2 Tudor domain 0.0082 16.5 0.0 6.4 7.3 0.0 3.6 3 BAHCC1-like_Tudor BAHCC1-like, Tudor domain ------ inclusion threshold ------ 0.022 15.0 0.0 0.36 11.1 0.0 2.3 2 Myosin_N Myosin N-terminal SH3-like domain 0.031 14.7 0.0 3.3 8.2 0.0 2.8 3 DUF4819 Domain of unknown function (DUF4819) 0.16 12.3 0.0 0.5 10.7 0.0 1.9 2 HIRAN HIRAN domain Domain annotation for each model (and alignments): >> DUF4537 Domain of unknown function (DUF4537) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 2.8e-05 0.1 58 101 .. 28 67 .. 13 78 .. 0.82 2 ! 23.9 0.0 1.3e-08 4.6e-05 3 108 .. 31 139 .. 30 145 .. 0.88 3 ! 10.6 0.0 0.00018 0.64 1 105 [. 149 259 .. 149 266 .. 0.70 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2.8e-05 DUF4537 58 vGDkVlalhdpaeqsYiPgvVlagvkkekeltVvfyngkkaklp 101 v D+Vla+++ ++ Y+Pg+V+ +++ + +V yng++ k FUN_000597-T1 28 VRDRVLARAQ--NSVYLPGEVT--EEEGSFFLVTLYNGQQMKHS 67 6699999864..678*******..89************987654 PP == domain 2 score: 23.9 bits; conditional E-value: 1.3e-08 DUF4537 3 kVlaRndedGfYyrgtvkkklsggvylvefdakdtqvveesdiisledak.erplkvGDkVlalhdpaeqs..YiPgvVlag..vkkekeltVvfy 93 +VlaR ++ Y +g v ++ +g +lv ++++++ + + +di+++ ++ + +GD+V+a +++ + s Y+ g V+ + +++ + + f FUN_000597-T1 31 RVLARA-QNSVYLPGEVTEE-EGSFFLVTLYNGQQMKHSYKDITAVVEDTlPAWVTLGDHVIASRPSTNGSgeYLMGFVTRDlcEGDDELYEITFH 124 799996.5789******987.67899******************9988777999**********777666666*******999988999******* PP DUF4537 94 ngkkaklpreevykl 108 n+++ ++ + ++kl FUN_000597-T1 125 NNQRRNCSLKDIRKL 139 *****9999988887 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00018 DUF4537 1 gqkVlaRndedGfYyrgtvkkkl...sggvylvef..dakdtqvveesdiisledak.erplkvGDkVlalhdpaeqsYiPgvVlag..vkkekel 88 g +V+aR++ Y+rg v +++ + ++ +++ + ++ +++ +i l+ ++ + +V++ h p Y+ g+V++ + ++ FUN_000597-T1 149 GARVFARWNG-TRYHRGFVAETVfvgQVLHLKIQLddAISVSHAASDERAIVLDVIPrYTQVHATQRVIG-HLPGTTAYVTGWVMKRnpNCWQDAY 242 6789****74.57**********64333344555554445555666677777775554777888888887.5678899*******77665557889 PP DUF4537 89 tVvfyngkkaklpreev 105 +Vvf ng + + + +e+ FUN_000597-T1 243 LVVFDNGGEREEDFNEI 259 99999988766655555 PP >> Tudor_5 Histone methyltransferase Tudor domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.077 2.8e+02 6 28 .. 31 49 .. 27 57 .. 0.82 2 ! 7.5 0.0 0.0014 5 2 41 .. 84 123 .. 83 135 .. 0.90 3 ! 7.7 0.1 0.0011 4.1 2 28 .. 147 169 .. 146 176 .. 0.89 4 ! 9.2 0.0 0.00038 1.4 6 44 .. 214 249 .. 202 253 .. 0.85 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.077 Tudor_5 6 RViAkykdsngkskyyaGviaep 28 RV A+ ++s y +G ++e FUN_000597-T1 31 RVLARA----QNSVYLPGEVTEE 49 888986....457*******996 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0014 Tudor_5 2 pvGtRViAkykdsngkskyyaGviaeppkelNkyrYlvfF 41 ++G ViA+ ++ng+ +y G ++ +e+++ Y ++F FUN_000597-T1 84 TLGDHVIASRPSTNGSGEYLMGFVTRDLCEGDDELYEITF 123 67889****7777*************************99 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0011 Tudor_5 2 pvGtRViAkykdsngkskyyaGviaep 28 +vG+RV A++ y G +ae FUN_000597-T1 147 QVGARVFARW----NGTRYHRGFVAET 169 69*******8....4579*******96 PP == domain 4 score: 9.2 bits; conditional E-value: 0.00038 Tudor_5 6 RViAkykdsngkskyyaGviaeppkelNkyrYlvfFDDG 44 RVi + g+ +y G + + + + Ylv FD+G FUN_000597-T1 214 RVIGHL---PGTTAYVTGWVMKRNPNCWQDAYLVVFDNG 249 777776...89999*****99998888899********9 PP >> Tudor_3 DNA repair protein Crb2 Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.1 0.00078 2.9 5 20 .. 13 28 .. 12 42 .. 0.88 2 ? -1.5 0.0 0.94 3.4e+03 3 23 .. 30 48 .. 28 52 .. 0.71 3 ? -2.4 0.0 1.7 6.3e+03 31 52 .] 118 139 .. 113 139 .. 0.77 4 ! 12.0 0.0 5.7e-05 0.21 3 39 .. 150 185 .. 148 190 .. 0.87 5 ? 2.9 0.0 0.039 1.4e+02 11 45 .. 221 255 .. 211 262 .. 0.69 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00078 Tudor_3 5 VfAlfkGkkraYYPAt 20 V Al++ ++ ++PA FUN_000597-T1 13 VIALWNTRSGGFFPAV 28 99*************6 PP == domain 2 score: -1.5 bits; conditional E-value: 0.94 Tudor_3 3 nrVfAlfkGkkraYYPAtclg 23 +rV+A +++ Y P+ + + FUN_000597-T1 30 DRVLARA--QNSVYLPGEVTE 48 7899975..568888887765 PP == domain 3 score: -2.4 bits; conditional E-value: 1.7 Tudor_3 31 rykVrFdDgtptevdskqvrrL 52 y++ F ++ + + k +r+L FUN_000597-T1 118 LYEITFHNNQRRNCSLKDIRKL 139 6999999998888888888876 PP == domain 4 score: 12.0 bits; conditional E-value: 5.7e-05 Tudor_3 3 nrVfAlfkGkkraYYPAtclgtsssgsk.rykVrFdDg 39 rVfA ++G Y+ + + +t+ g+ +k++ dD FUN_000597-T1 150 ARVFARWNG--TRYHRGFVAETVFVGQVlHLKIQLDDA 185 69*******..999999999999999888999998885 PP == domain 5 score: 2.9 bits; conditional E-value: 0.039 Tudor_3 11 GkkraYYPAtclgtsssgsk.rykVrFdDgtptevd 45 G + aY +++++++ + + y+V Fd g e d FUN_000597-T1 221 G-TTAYVTGWVMKRNPNCWQdAYLVVFDNGGEREED 255 4.66777777777777776689******99776655 PP >> BAHCC1-like_Tudor BAHCC1-like, Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.096 3.5e+02 41 65 .. 116 140 .. 104 142 .. 0.84 2 ? 3.0 0.0 0.038 1.4e+02 8 33 .. 147 174 .. 140 204 .. 0.53 3 ! 7.3 0.0 0.0018 6.4 37 66 .. 235 264 .. 220 265 .. 0.77 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.096 BAHCC1-like_Tudor 41 kklvaVefDDGDsgriplediRlLp 65 ++l ++ f +++ +l+diR Lp FUN_000597-T1 116 DELYEITFHNNQRRNCSLKDIRKLP 140 567789999999**********998 PP == domain 2 score: 3.0 bits; conditional E-value: 0.038 BAHCC1-like_Tudor 8 peGtRvcayWSqq.yrc.LYpGtvaess 33 + G+Rv a W + y+ + tv ++ FUN_000597-T1 147 QVGARVFARWNGTrYHRgFVAETVFVGQ 174 6799******854354313333443333 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0018 BAHCC1-like_Tudor 37 peedkklvaVefDDGDsgriplediRlLpe 66 p+ + V fD G +++ + ++iR+Lp+ FUN_000597-T1 235 PNCWQDAYLVVFDNGGEREEDFNEIRILPP 264 33444566799*****************96 PP >> Myosin_N Myosin N-terminal SH3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 9.9e-05 0.36 14 43 .. 40 69 .. 37 71 .. 0.86 2 ? 1.3 0.0 0.12 4.3e+02 14 24 .. 224 234 .. 222 253 .. 0.79 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 9.9e-05 Myosin_N 14 gfvkGeikeeegdkvtVetedGktvtVkkd 43 ++ Ge++eeeg ++V++ +G++++ + FUN_000597-T1 40 VYLPGEVTEEEGSFFLVTLYNGQQMKHSYK 69 599*******************99876555 PP == domain 2 score: 1.3 bits; conditional E-value: 0.12 Myosin_N 14 gfvkGeikeee 24 ++v G++ +++ FUN_000597-T1 224 AYVTGWVMKRN 234 9******8887 PP >> DUF4819 Domain of unknown function (DUF4819) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.035 1.3e+02 28 63 .. 34 67 .. 25 93 .. 0.77 2 ? -0.9 0.0 0.65 2.4e+03 3 42 .. 74 109 .. 70 134 .. 0.65 3 ? 8.2 0.0 0.0009 3.3 2 61 .. 197 253 .. 196 265 .. 0.82 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.035 DUF4819 28 eeksekvyvegvvvevnekpvrfvVklseekeaees 63 + +++vy+ g+v+e + f V l+++++ ++s FUN_000597-T1 34 ARAQNSVYLPGEVTEE--EGSFFLVTLYNGQQMKHS 67 567899*******985..677899999999988765 PP == domain 2 score: -0.9 bits; conditional E-value: 0.65 DUF4819 3 vilDasPslsevavgtrvcvrveeeeeksekvyvegvvve 42 v++D P+ v++g +v ++++++ y+ g v+ FUN_000597-T1 74 VVEDTLPAW--VTLGDHVIAS--RPSTNGSGEYLMGFVTR 109 777777754..6777777766..67777777888888853 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0009 DUF4819 2 dvilDasPslsevavgtrvcvrveeeeeksekvyvegvvvevnekp..vrfvVklseekeae 61 +++lD+ P +v++ rv ++++yv+g v++ n + + V + ++ e+e FUN_000597-T1 197 AIVLDVIPRYTQVHATQRVIGH-----LPGTTAYVTGWVMKRNPNCwqDAYLVVFDNGGERE 253 589*************999876.....7899*********9998875567888777776665 PP >> HIRAN HIRAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 2.6 9.4e+03 21 34 .. 84 97 .. 72 113 .. 0.66 2 ? 10.7 0.0 0.00014 0.5 10 68 .. 158 233 .. 151 253 .. 0.89 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 2.6 HIRAN 21 kigeivklvrepqn 34 + g++v+ r+++n FUN_000597-T1 84 TLGDHVIASRPSTN 97 55666666666555 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00014 HIRAN 10 gtrYysg..trklkigeivklvrep.......qnpydsnavrvyt........edgeeiGylprevakilapllds 68 gtrY+ g ++++ +g+ ++l+ + + + d a+ + ++iG+lp +a++ +++++ FUN_000597-T1 158 GTRYHRGfvAETVFVGQVLHLKIQLddaisvsHAASDERAIVLDViprytqvhATQRVIGHLPGTTAYVTGWVMKR 233 99*****99999999999999999999****99999*****99999999888777779***********9999965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (269 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 452 (0.0176943); expected 510.9 (0.02) Passed bias filter: 433 (0.0169505); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2692.18 // Query: FUN_000598-T1 [L=108] Description: FUN_000598 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (108 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 258 (0.0100998); expected 510.9 (0.02) Passed bias filter: 242 (0.00947348); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1107.94 // Query: FUN_000599-T1 [L=314] Description: FUN_000599 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-36 125.9 24.2 1.2e-34 120.4 24.2 2.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.017 15.3 1.4 0.017 15.3 1.4 2.5 2 DUF7358 Domain of unknown function (DUF7358) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 120.4 24.2 9.6e-39 1.2e-34 1 260 [] 39 283 .. 39 283 .. 0.92 Alignments for each domain: == domain 1 score: 120.4 bits; conditional E-value: 9.6e-39 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN lV+l+i+r + +t++n f+ +L vaD+ v+l++ p+++++ +l + w+ ++ ++ ++ + +++a l+l+a+s+DR++a+++ ++ ++i FUN_000599-T1 39 GNALVLLAIYRVPSQKTVSNAFIASLGVADFSVGLIMNPLWVYKSVL-NIWQSDNIISTVIEVVAMQTVVATSLSLCAVSLDRFIAVTN-IRHNEI 132 8*********************************9999****99996.****************************************9.66668* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx... RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks... 189 +t r++++i+ +W+++++++ + l++++ +++p+ + + +++++++lp+lvi++cy+ +++++r + k+ ++ FUN_000599-T1 133 VTCNRVRTVIISIWIFSVIFASLRLVVTD--P-----------FELPK--------LWIAATTITVILPCLVISICYFYMVKAARVQIKRITKnea 207 **************************653..2...........56777........788889999999***********************99566 PP .....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ ++ k++ka+ t+++vv+vf++cw+P +++++++ ++++ ++++ ++ + + l ++ns++NP+iY FUN_000599-T1 208 ctvngDEAVARLKNSKAVFTVVIVVGVFLVCWTPSLVISFVQFFCNDPCKRTKLNGYWFWGALAEFSNSAFNPFIY 283 666554444445555*****************************9999999************************* PP >> DUF7358 Domain of unknown function (DUF7358) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.8 6.2 1.8 2.3e+04 55 55 .. 97 97 .. 17 161 .. 0.55 2 ? 15.3 1.4 1.3e-06 0.017 93 177 .. 167 252 .. 165 256 .. 0.85 Alignments for each domain: == domain 1 score: -4.8 bits; conditional E-value: 1.8 DUF7358 55 m 55 + FUN_000599-T1 97 V 97 1 PP == domain 2 score: 15.3 bits; conditional E-value: 1.3e-06 DUF7358 93 krwlwwtrfglvvtvlqfvgalylvlsiakdlskd.ekssecllgeksnekwkkkllvlflvlvllvailqcftgsdvlrWrsfYa 177 k w++ t +++++ l + + + ++++a+ k +k+++c+++ ++ ++ k+ ++f+v++++ ++l c t s v+++ f+ FUN_000599-T1 167 KLWIAATTITVILPCLVISICYFYMVKAARVQIKRiTKNEACTVNGDEAVARLKNSKAVFTVVIVVGVFLVCWTPSLVISFVQFFC 252 67999999999999999988888888888765555167888999999889999**************************9999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (314 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1379 (0.0539832); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 3070.99 // Query: FUN_000600-T1 [L=1274] Description: FUN_000600 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-81 272.2 0.0 1.4e-80 271.7 0.0 1.2 1 GT4-conflict Family 4 Glycosyltransferase in conflict sys 2.5e-69 224.4 69.0 7e-07 29.3 0.1 13.6 13 LRR_6 Leucine Rich repeat 1.4e-24 87.3 0.0 2.8e-24 86.3 0.0 1.6 1 NACHT NACHT domain 2.3e-17 63.6 0.0 5e-17 62.5 0.0 1.5 1 Glycos_transf_1 Glycosyl transferases group 1 3.3e-17 63.6 0.0 8.1e-17 62.3 0.0 1.7 1 Glyco_trans_1_4 Glycosyl transferases group 1 1.5e-14 51.5 32.3 8.6 7.5 0.1 12.7 12 LRR_1 Leucine Rich Repeat 6.7e-11 42.5 53.3 0.0028 18.3 1.1 8.2 9 LRR_4 Leucine Rich repeats (2 copies) 3.4e-09 37.9 0.0 9.3e-09 36.5 0.0 1.8 1 AAA_16 AAA ATPase domain 1.4e-07 32.3 0.2 0.00084 20.0 0.1 3.0 3 NPHP3_N Nephrocystin 3, N-terminal 5.7e-06 26.5 0.0 2.4e-05 24.4 0.0 1.9 2 NB-ARC NB-ARC domain 6e-05 23.8 0.0 0.00023 21.9 0.0 2.0 1 AAA_22 AAA domain 8.8e-05 22.7 0.0 0.00033 20.8 0.0 1.9 2 nSTAND3 Novel STAND NTPase 3 0.00017 21.9 0.0 0.0026 18.1 0.0 2.4 2 nSTAND_NTPase5 Novel STAND NTPase 5 0.00028 20.0 2.3 1.8 7.5 0.1 3.9 5 RESC10 RNA-editing substrate-binding complex 10 pro 0.00046 20.4 47.7 0.55 10.5 5.6 8.0 7 LRR_8 Leucine rich repeat 0.0049 17.0 0.0 0.012 15.7 0.0 1.6 1 AAA_25 AAA domain ------ inclusion threshold ------ 0.02 14.6 0.0 0.51 10.0 0.1 2.2 2 KAP_NTPase KAP family P-loop domain 0.079 13.9 0.0 0.19 12.6 0.0 1.7 1 AAA ATPase family associated with various cellul 0.081 13.9 0.0 0.27 12.2 0.0 1.9 1 RNA_helicase RNA helicase 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 VapE-like_dom Virulence-associated protein E-like domain 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 Zeta_toxin Zeta toxin 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 TniB Bacterial TniB protein 0.17 11.7 0.0 0.44 10.4 0.0 1.7 2 ATPase KaiC 0.22 11.9 0.2 20 5.5 0.1 2.7 3 OmcA-like_N OmcA-like N-terminal domain 0.22 11.0 0.1 0.33 10.4 0.1 1.2 1 P2X_receptor ATP P2X receptor Domain annotation for each model (and alignments): >> GT4-conflict Family 4 Glycosyltransferase in conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 271.7 0.0 1.3e-83 1.4e-80 2 385 .] 19 384 .. 18 384 .. 0.93 Alignments for each domain: == domain 1 score: 271.7 bits; conditional E-value: 1.3e-83 GT4-conflict 2 vvatewssakGGistfNreLceaLAaaga.eviclVpeaseeeiadAkaagVrLvkaeaepgvsereslllrrpelpagvepdlviGHgrvtGpaA 96 ++a ew+s++GG+st+NreL++ LA+ ++ ev+ p+ s+++ ++Ak++g+ +v+ae++pg +e l+ p+ ++ d+viGHg G+ A FUN_000600-T1 19 ILASEWGSSNGGLSTINRELAIQLAKSQDvEVTFFLPKCSHKNKEEAKRHGISIVEAERKPGYEELD-WLSFPPQ---DLLIDIVIGHGVKLGKQA 110 5799***********************999***********************************99.5555544...5667************** PP GT4-conflict 97 kalaedfypdakrvhfvHmapdelewlkekrdaaeraeerekierelaakAdlvvaVGprLaeearrllseapgepkvleldpgfdveaeeeprtp 192 +++++ + ++k v++vH++p++l ++k +++ ++e+++ +e+el++ Adlvv+VGp+L+e +r+ l+ ++++++v e++p + +++++ +++ FUN_000600-T1 111 QVIRNYH--KCKWVQVVHTDPEKLGMFKCYENPISKGEQKHHVEVELCQMADLVVGVGPKLTEAFRKYLRWCKKDQDVFEFTPSVFTDFASVEQAL 204 ****998..*****************************************************************************9999878888 PP GT4-conflict 193 peggklkvLllGRae..DaelKgldlAaravgrlakesrderveLvvrGapaeeaeelrerlaeiagepalevtvrpytkdraeleadlrraslvl 286 e++ ++vL++GR + D +lKg d+Aar v++l + +Lv +Ga +++ +e ++rl + +g p+ ++tvr ++ dr++l++ + + +lvl FUN_000600-T1 205 DERKVHSVLVFGRGDdeDFKLKGFDIAARSVAALPD------TDLVFVGAVDGKEQEIAKRLLD-SGIPQGRLTVRGFK-DREALKQLFCEVDLVL 292 89************988999***********88866......67*******************9.79999********5.899************* PP GT4-conflict 287 mPSraEGFGLvglEAiaagvPvLvsseSGlaelLeek.lseeeaerlvvpvtgddeedaeewaraieevlr.dleaaferaaelreeLaerltWaa 380 mPSr+EGFGL+glEA++ag+Pv+vs++SG++e L + + ++++v++ ++d+ +w++ai +++ d++++ ++++ l e ++++ W + FUN_000600-T1 293 MPSRTEGFGLTGLEALSAGLPVIVSKNSGFGEALGSVpF----GSSFVID-SEDP----SAWTAAISGIWNkDRQTRLDETKVLGESYKRKYGWFE 379 **********************************99923....5567777.4444....7*********9538999999999999999999***98 PP GT4-conflict 381 aaasL 385 +++L FUN_000600-T1 380 QCENL 384 88765 PP >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 1.6e-07 0.00017 1 24 [] 924 947 .. 924 947 .. 0.95 2 ! 22.7 0.1 8.8e-08 8.9e-05 1 23 [. 952 974 .. 952 975 .. 0.92 3 ! 28.1 0.3 1.7e-09 1.7e-06 2 24 .] 981 1003 .. 980 1003 .. 0.96 4 ! 29.3 0.1 6.9e-10 7e-07 1 24 [] 1008 1031 .. 1008 1031 .. 0.95 5 ! 29.3 0.1 6.9e-10 7e-07 1 24 [] 1036 1059 .. 1036 1059 .. 0.95 6 ! 19.8 0.6 7.8e-07 0.0008 1 23 [. 1064 1086 .. 1064 1087 .. 0.92 7 ! 16.3 0.1 1e-05 0.01 1 24 [] 1092 1115 .. 1092 1115 .. 0.95 8 ! 19.3 1.0 1.1e-06 0.0012 1 23 [. 1120 1142 .. 1120 1143 .. 0.92 9 ! 19.6 1.2 9e-07 0.00092 1 23 [. 1148 1170 .. 1148 1171 .. 0.91 10 ! 18.8 0.5 1.6e-06 0.0017 1 23 [. 1176 1198 .. 1176 1199 .. 0.92 11 ! 19.2 0.5 1.2e-06 0.0013 1 23 [. 1204 1226 .. 1204 1227 .. 0.91 12 ! 21.9 1.5 1.6e-07 0.00017 1 23 [. 1232 1254 .. 1232 1255 .. 0.92 13 ? 2.0 0.2 0.39 3.9e+02 1 12 [. 1260 1271 .. 1260 1272 .. 0.90 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 1.6e-07 LRR_6 1 hnttLteLdLsgNdIgDeGleaLa 24 +nt+Lt+L+L +IgD+G++aL+ FUN_000600-T1 924 VNTSLTSLNLFQTRIGDKGVKALS 947 59********************96 PP == domain 2 score: 22.7 bits; conditional E-value: 8.8e-08 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L Ls+N IgDeG+ +L FUN_000600-T1 952 VNTSLTSLYLSFNSIGDEGANSL 974 59*****************9777 PP == domain 3 score: 28.1 bits; conditional E-value: 1.7e-09 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 nt+Lt+LdL+ N IgDeG++aL+ FUN_000600-T1 981 NTSLTSLDLTRNSIGDEGIKALS 1003 9********************96 PP == domain 4 score: 29.3 bits; conditional E-value: 6.9e-10 LRR_6 1 hnttLteLdLsgNdIgDeGleaLa 24 +nt+Lt+LdL+ N IgDeG++aL+ FUN_000600-T1 1008 VNTSLTSLDLTRNSIGDEGVKALS 1031 59********************96 PP == domain 5 score: 29.3 bits; conditional E-value: 6.9e-10 LRR_6 1 hnttLteLdLsgNdIgDeGleaLa 24 +nt+Lt+LdL+ N IgDeG++aL+ FUN_000600-T1 1036 VNTSLTSLDLTRNSIGDEGVKALS 1059 59********************96 PP == domain 6 score: 19.8 bits; conditional E-value: 7.8e-07 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L+L +N+I+DeG+ +L FUN_000600-T1 1064 VNTSLTSLNLCYNCISDEGANSL 1086 59*****************9777 PP == domain 7 score: 16.3 bits; conditional E-value: 1e-05 LRR_6 1 hnttLteLdLsgNdIgDeGleaLa 24 +nt+Lt+LdL IgDeG++aL+ FUN_000600-T1 1092 VNTSLTSLDLKRDSIGDEGVKALS 1115 59********************96 PP == domain 8 score: 19.3 bits; conditional E-value: 1.1e-06 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L+L N+IgDeG+ +L FUN_000600-T1 1120 VNTSLTSLNLCQNHIGDEGANSL 1142 59*****************9777 PP == domain 9 score: 19.6 bits; conditional E-value: 9e-07 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +n++Lt+L+L +N IgDeG+ +L FUN_000600-T1 1148 VNSSLTSLNLCHNTIGDEGANSL 1170 599****************9777 PP == domain 10 score: 18.8 bits; conditional E-value: 1.6e-06 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L+L N+IgDeG+ +L FUN_000600-T1 1176 VNTSLTSLNLCQNRIGDEGANSL 1198 59*****************9777 PP == domain 11 score: 19.2 bits; conditional E-value: 1.2e-06 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +n++Lt+L+L +N IgDeG+ +L FUN_000600-T1 1204 VNSSLTSLNLCYNTIGDEGANSL 1226 599****************9777 PP == domain 12 score: 21.9 bits; conditional E-value: 1.6e-07 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L+L +N+IgDeG+ +L FUN_000600-T1 1232 VNTSLTSLNLCHNCIGDEGANSL 1254 59*****************9777 PP == domain 13 score: 2.0 bits; conditional E-value: 0.39 LRR_6 1 hnttLteLdLsg 12 +nt+Lt+ +Lsg FUN_000600-T1 1260 VNTSLTSFHLSG 1271 59********98 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 86.3 0.0 2.7e-27 2.8e-24 2 166 .. 499 655 .. 498 656 .. 0.91 Alignments for each domain: == domain 1 score: 86.3 bits; conditional E-value: 2.7e-27 NACHT 2 tvilqGeaGsGKTtLlqklalawaegklpqda.....fklvFflslrelsrsgkalsladllfsqlpepaapvseviavllelperlLlilDGlDe 92 +v+++Ge+G+GKTt +kla +wa+ + + +++++l++re++ s + +++++ + ep+ + +i++l ++p ++Ll+lDGlDe FUN_000600-T1 499 VVLIEGEPGMGKTTYCRKLAYDWATTQGRKWDksfprIEVLLLLRCREIESSIWE-AIDEQILPEDIEPEVRDM-FIQFLSKNPSKVLLVLDGLDE 592 89**********************99877755566668999*********98766.999999998888888774.6******************** PP NACHT 93 lksqlgqpkekqpvrtlLssllrkkllpeasllltvrpdalrklregleeaavlevegfseedrkeyvrkyfsd 166 ++ ++ tl+ +l++k+ lp+++++lt+r +a +++r + + le+ gf++ d+++++rkyf++ FUN_000600-T1 593 ADP--EK-------LTLFCKLVQKEKLPGCFIVLTSRHEAESNIRPYTDTL--LEIVGFTRTDAECFIRKYFEK 655 *97..33.......68*********************************99..*******************86 PP >> Glycos_transf_1 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.5 0.0 4.9e-20 5e-17 28 158 .. 226 355 .. 220 365 .. 0.90 Alignments for each domain: == domain 1 score: 62.5 bits; conditional E-value: 4.9e-20 Glycos_transf_1 28 KgldlllkafaklkeklkpdlklviaG..dgeeekklkklaeklglednvkflgfvsdedlpellkiadvfvlpsrsEgfGivllEAmaaglpv 119 Kg+d + +++a pd+ lv++G dg+e++ k+l ++ + ++++ gf+++e+l++l+ d++++psr+EgfG++ lEA++aglpv FUN_000600-T1 226 KGFDIAARSVAA-----LPDTDLVFVGavDGKEQEIAKRLLDSGIPQGRLTVRGFKDREALKQLFCEVDLVLMPSRTEGFGLTGLEALSAGLPV 314 677777777775.....599************************************************************************** PP Glycos_transf_1 120 iasdvgglrevvkdge..tGllvkpnnaealaeaieklled 158 i+s+++g+ e +++ + ++++++++ a+ +ai + ++ FUN_000600-T1 315 IVSKNSGFGEALGSVPfgSSFVIDSEDPSAWTAAISGIWNK 355 ************98766699***********9999876655 PP >> Glyco_trans_1_4 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.3 0.0 8e-20 8.1e-17 4 139 .. 212 353 .. 209 355 .. 0.81 Alignments for each domain: == domain 1 score: 62.3 bits; conditional E-value: 8e-20 Glyco_trans_1_4 4 ilfvGrl.ae..nekgvdllleavplvrkkerdvrlvivGdgpeeeeeleelak..gledr.veftGfv..edlaellaaadvfvlPslsegfg 89 +l +Gr +e + kg+d+ ++ v+++ + + lv+vG + +e+e+ +++ g+ ++ ++ Gf e l++l+ + d++++Ps++egfg FUN_000600-T1 212 VLVFGRGdDEdfKLKGFDIAARSVAALPD----TDLVFVGAVDGKEQEIAKRLLdsGIPQGrLTVRGFKdrEALKQLFCEVDLVLMPSRTEGFG 301 66777775556788999999999999993....57999995542445776655338988667*******8666********************* PP Glyco_trans_1_4 90 lkllEAmaaglPvVatdvggipevvedg....engllvppgdpealaeailrll 139 l+ lEA++aglPv++++ +g+ e++ g + ++++++dp a+ +ai ++ FUN_000600-T1 302 LTGLEALSAGLPVIVSKNSGFGEAL--GsvpfGSSFVIDSEDPSAWTAAISGIW 353 ***********************99..64444445**************98765 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.7 1.7e+03 1 20 [. 927 946 .. 927 949 .. 0.81 2 ! 7.5 0.1 0.0084 8.6 1 21 [. 955 975 .. 955 977 .. 0.87 3 ? 6.4 0.0 0.021 21 1 21 [. 983 1003 .. 983 1005 .. 0.85 4 ? 5.9 0.0 0.031 31 1 20 [. 1011 1030 .. 1011 1033 .. 0.83 5 ? 5.9 0.0 0.031 31 1 20 [. 1039 1058 .. 1039 1061 .. 0.83 6 ? 6.7 0.4 0.017 17 1 21 [. 1067 1087 .. 1067 1089 .. 0.89 7 ? -1.2 0.0 7.1 7.2e+03 1 17 [. 1095 1111 .. 1095 1116 .. 0.74 8 ? 6.0 0.1 0.027 28 1 21 [. 1123 1143 .. 1123 1145 .. 0.87 9 ? 6.5 0.1 0.018 19 1 21 [. 1151 1171 .. 1151 1173 .. 0.87 10 ? 6.2 0.1 0.024 24 1 21 [. 1179 1199 .. 1179 1201 .. 0.87 11 ? 5.6 0.1 0.036 37 1 21 [. 1207 1227 .. 1207 1229 .. 0.87 12 ? 6.6 0.3 0.018 18 1 21 [. 1235 1255 .. 1235 1257 .. 0.87 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.7 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L++L+L ++++++ +l FUN_000600-T1 927 SLTSLNLFQTRIGDKGVKAL 946 79*********987776666 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0084 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+Ls N+++++ +sl+ FUN_000600-T1 955 SLTSLYLSFNSIGDEGANSLS 975 79**********988888876 PP == domain 3 score: 6.4 bits; conditional E-value: 0.021 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++LdL +N+++++ + +l+ FUN_000600-T1 983 SLTSLDLTRNSIGDEGIKALS 1003 79**********888877765 PP == domain 4 score: 5.9 bits; conditional E-value: 0.031 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L++LdL +N+++++ +l FUN_000600-T1 1011 SLTSLDLTRNSIGDEGVKAL 1030 79**********87777666 PP == domain 5 score: 5.9 bits; conditional E-value: 0.031 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L++LdL +N+++++ +l FUN_000600-T1 1039 SLTSLDLTRNSIGDEGVKAL 1058 79**********87777666 PP == domain 6 score: 6.7 bits; conditional E-value: 0.017 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+L++N +s++ +sl+ FUN_000600-T1 1067 SLTSLNLCYNCISDEGANSLS 1087 79**********999988886 PP == domain 7 score: -1.2 bits; conditional E-value: 7.1 LRR_1 1 nLeeLdLsnNnlsgllp 17 +L++LdL + +++++ FUN_000600-T1 1095 SLTSLDLKRDSIGDEGV 1111 79*****9888866555 PP == domain 8 score: 6.0 bits; conditional E-value: 0.027 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+L+ N+++++ +sl+ FUN_000600-T1 1123 SLTSLNLCQNHIGDEGANSLS 1143 79**********988888876 PP == domain 9 score: 6.5 bits; conditional E-value: 0.018 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+L++N ++++ +sl+ FUN_000600-T1 1151 SLTSLNLCHNTIGDEGANSLS 1171 79**********988888876 PP == domain 10 score: 6.2 bits; conditional E-value: 0.024 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+L+ N+++++ +sl+ FUN_000600-T1 1179 SLTSLNLCQNRIGDEGANSLS 1199 79**********988888876 PP == domain 11 score: 5.6 bits; conditional E-value: 0.036 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+L++N ++++ +sl+ FUN_000600-T1 1207 SLTSLNLCYNTIGDEGANSLS 1227 79**********988888876 PP == domain 12 score: 6.6 bits; conditional E-value: 0.018 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+L++N ++++ +sl+ FUN_000600-T1 1235 SLTSLNLCHNCIGDEGANSLS 1255 79**********988888876 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 0.53 5.4e+02 1 14 [. 926 939 .. 911 951 .. 0.71 2 ! 18.3 1.1 2.8e-06 0.0028 1 36 [. 954 994 .. 954 1004 .. 0.84 3 ! 12.2 0.7 0.00024 0.24 1 36 [. 1010 1050 .. 1010 1054 .. 0.84 4 ! 11.8 1.5 0.00032 0.33 1 32 [. 1066 1103 .. 1066 1109 .. 0.82 5 ! 9.2 4.2 0.002 2.1 1 36 [. 1122 1162 .. 1122 1171 .. 0.84 6 ! 12.4 2.1 0.00021 0.22 2 38 .. 1151 1192 .. 1150 1195 .. 0.85 7 ! 9.4 3.8 0.0018 1.8 1 36 [. 1178 1218 .. 1178 1228 .. 0.83 8 ! 10.3 3.7 0.00094 0.96 2 38 .. 1207 1248 .. 1206 1255 .. 0.84 9 ! 8.7 1.1 0.003 3.1 1 32 [. 1234 1271 .. 1234 1273 .. 0.83 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.53 LRR_4 1 pnLetLdLsnNrit 14 ++L++L+L +ri FUN_000600-T1 926 TSLTSLNLFQTRIG 939 35555555555554 PP == domain 2 score: 18.3 bits; conditional E-value: 2.8e-06 LRR_4 1 pnLetLdLsnNritdidp..ls....kLpnLetLdLsgNnki 36 ++L++L+Ls N+i d + ls + ++L++LdL++N i FUN_000600-T1 954 TSLTSLYLSFNSIGDEGAnsLSqalrGNTSLTSLDLTRN-SI 994 79*************999994455559*********888.55 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00024 LRR_4 1 pnLetLdLsnNritdidp..ls...k.LpnLetLdLsgNnki 36 ++L++LdL N+i d + ls ++L++LdL++N i FUN_000600-T1 1010 TSLTSLDLTRNSIGDEGVkaLSqalRvNTSLTSLDLTRN-SI 1050 79*************999885567755*********888.44 PP == domain 4 score: 11.8 bits; conditional E-value: 0.00032 LRR_4 1 pnLetLdLsnNritdidp..ls...k.LpnLetLdLsg 32 ++L++L+L +N+i+d + ls ++L++LdL + FUN_000600-T1 1066 TSLTSLNLCYNCISDEGAnsLSqtlRvNTSLTSLDLKR 1103 79*************999995567744********944 PP == domain 5 score: 9.2 bits; conditional E-value: 0.002 LRR_4 1 pnLetLdLsnNritdidp..ls...k.LpnLetLdLsgNnki 36 ++L++L+L N+i d + ls +L++L+L +N i FUN_000600-T1 1122 TSLTSLNLCQNHIGDEGAnsLSqalRvNSSLTSLNLCHN-TI 1162 79*************999995566744999******777.55 PP == domain 6 score: 12.4 bits; conditional E-value: 0.00021 LRR_4 2 nLetLdLsnNritdidp..ls...k.LpnLetLdLsgNnkitd 38 +L++L+L +N i d + ls ++L++L+L +N +i d FUN_000600-T1 1151 SLTSLNLCHNTIGDEGAnsLSqalRvNTSLTSLNLCQN-RIGD 1192 8*************999995567744*********777.8865 PP == domain 7 score: 9.4 bits; conditional E-value: 0.0018 LRR_4 1 pnLetLdLsnNritdidp..ls...k.LpnLetLdLsgNnki 36 ++L++L+L Nri d + ls +L++L+L N i FUN_000600-T1 1178 TSLTSLNLCQNRIGDEGAnsLSqalRvNSSLTSLNLCYN-TI 1218 79*************999995566744999******666.55 PP == domain 8 score: 10.3 bits; conditional E-value: 0.00094 LRR_4 2 nLetLdLsnNritdidp..ls...k.LpnLetLdLsgNnkitd 38 +L++L+L +N i d + ls ++L++L+L +N +i d FUN_000600-T1 1207 SLTSLNLCYNTIGDEGAnsLSqalRvNTSLTSLNLCHN-CIGD 1248 8*************999995567744*********666.7765 PP == domain 9 score: 8.7 bits; conditional E-value: 0.003 LRR_4 1 pnLetLdLsnNritdidp..ls...k.LpnLetLdLsg 32 ++L++L+L +N+i d + ls ++L++ +Lsg FUN_000600-T1 1234 TSLTSLNLCHNCIGDEGAnsLSqtlRvNTSLTSFHLSG 1271 79************999888556664499999999977 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.0 9.1e-12 9.3e-09 8 165 .. 480 612 .. 478 616 .. 0.67 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 9.1e-12 AAA_16 8 eleaLlallervrsgrp.plvlvsGeaGvGKSalvrellraleraalvlsgkcdelqrglpyaallealtresllrqllaeseaallaawraalle 102 e++ ++ ++++ + r +vl+ Ge+G+GK++ +r+l+ +++ k+d + p + + ll ++e e++ +a ++++l FUN_000600-T1 480 EVNSMTSIFKPHEDCRRpKVVLIEGEPGMGKTTYCRKLAYDWATT---QGRKWDKS---FP------RI-E-VLLLLRCREIESSIWEAIDEQILP 561 5666666676666555459********************655544...55666766...33......34.2.455555555444454444444333 PP AAA_16 103 elaavpalegeeaerllealsrllalaarkerplvlvlDdlqwadeasldllaaLlrlleskp 165 e + + +++ ++++l +++ ++lvlD+l++ad++ l+l++ L++ ++ FUN_000600-T1 562 E---------DIEPEVRDMFIQFL---SKNPSKVLLVLDGLDEADPEKLTLFCKLVQKEKLPG 612 2.........22356888888888...333444**********************99877654 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 8.6 8.8e+03 68 100 .. 31 63 .. 26 71 .. 0.70 2 ! 8.8 0.0 0.0024 2.4 20 45 .. 495 520 .. 484 533 .. 0.80 3 ! 20.0 0.1 8.2e-07 0.00084 82 164 .] 543 620 .. 533 620 .. 0.77 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 8.6 NPHP3_N 68 lssllrsllhqlasqlpelreelleklaedlgl 100 ls++ r l+ qla++++ + +l k++++++ FUN_000600-T1 31 LSTINRELAIQLAKSQDVEVTFFLPKCSHKNKE 63 567888999999988777667777777665544 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0024 NPHP3_N 20 sdssllwlsGkpGsGKsvlastvidh 45 ++++++ + G+pG+GK++ ++ ++ + FUN_000600-T1 495 RRPKVVLIEGEPGMGKTTYCRKLAYD 520 4578999*************998754 PP == domain 3 score: 20.0 bits; conditional E-value: 8.2e-07 NPHP3_N 82 qlpelreelleklaedlgldekdlrelweklletlllakslsrpvyiviDALDEceeseellellaellsksk.sklkvlvtSR 164 + +e+ ++++e+++e+ + +d ++ +++++ ++l ++++++v +v+D+LDE + ++ l+l+++l++k+k + + +++tSR FUN_000600-T1 543 RCREIESSIWEAIDEQ--ILPEDIEPEVRDMFIQFL--SKNPSKVLLVLDGLDEADPEK--LTLFCKLVQKEKlPGCFIVLTSR 620 5567777888887765..456788999999998877..567899***********9876..56777777777625699999999 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2.3 2.4e+03 42 63 .. 109 130 .. 106 158 .. 0.78 2 ! 24.4 0.0 2.4e-08 2.4e-05 17 144 .. 496 628 .. 482 656 .. 0.79 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2.3 NB-ARC 42 lsevegrFdvvawvvvsktfse 63 ++v +++ + wv+v +t+ e FUN_000600-T1 109 QAQVIRNYHKCKWVQVVHTDPE 130 57999**********9988755 PP == domain 2 score: 24.4 bits; conditional E-value: 2.4e-08 NB-ARC 17 elqivalvGmgGvGKttLakeifnklseveg.rFd.vvawvvvsktfseeelledilkeLgkeeddldekeeselaeklrrlLltk..rfllvlDD 108 +++v + G +G+GKtt ++ + ++++g ++d ++ + v +e+ +i++ + ++ l e e e ++ ++L + ++llvlD FUN_000600-T1 496 RPKVVLIEGEPGMGKTTYCRKLAYDWATTQGrKWDkSFPRIEVLLLLRCREIESSIWEAIDEQ--ILPEDIEPEVRDMFIQFLSKNpsKVLLVLDG 589 4679*********************99999889**9999*********************444..44444556799999999999999******97 PP NB-ARC 109 vwee..edweki.gvvlpdrenkskvllTtRseevaeav 144 e e++ ++v +++ ++ ++lT+R e+ +++ FUN_000600-T1 590 LDEAdpEKLTLFcKLVQKEKLPGCFIVLTSRHEAESNIR 628 64431044544414566667779********99876655 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 2.3e-07 0.00023 5 109 .. 497 606 .. 494 625 .. 0.77 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 2.3e-07 AAA_22 5 agilvltGesGtGKTtllrrll.eqldee....ddsvvlvelpsstspkdllrellralglelekelskeellaalqealkalaaravliiDEaqn 95 +++++ Ge+G+GKTt +r+l+ ++++ + d+s+ ++e+ +++ + +a++++ e+ + e+++++ + l++ ++++l++D + FUN_000600-T1 497 PKVVLIEGEPGMGKTTYCRKLAyDWATTQgrkwDKSFPRIEVLLLLRCREIESSIWEAIDEQILPEDIEPEVRDMFIQFLSKNPSKVLLVLDGLDE 592 67899***************98345555599*96666666666666668888888888888888878889999*********************** PP AAA_22 96 lseelleeLrslln 109 +e l + +l++ FUN_000600-T1 593 ADPEKLTLFCKLVQ 606 98888888777766 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 3.3e-07 0.00033 17 43 .. 497 523 .. 486 560 .. 0.83 2 ? -2.4 0.0 4.7 4.8e+03 88 119 .. 595 628 .. 588 649 .. 0.77 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 3.3e-07 nSTAND3 17 nkvviitGepGiGKttlaemLalklld 43 kvv+i GepG+GKtt ++ La++++ FUN_000600-T1 497 PKVVLIEGEPGMGKTTYCRKLAYDWAT 523 689********************9987 PP == domain 2 score: -2.4 bits; conditional E-value: 4.7 nSTAND3 88 dskllsfikrirksknk.k.lilTtReyilnqak 119 +kl+ f+k ++k+k ++lT+R++ ++ + FUN_000600-T1 595 PEKLTLFCKLVQKEKLPgCfIVLTSRHEAESNIR 628 5688889999998888887799***998655555 PP >> nSTAND_NTPase5 Novel STAND NTPase 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.0 2.5e-06 0.0026 36 70 .. 492 526 .. 472 530 .. 0.81 2 ? 0.7 0.0 0.6 6.1e+02 90 135 .. 576 622 .. 555 630 .. 0.70 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 2.5e-06 nSTAND_NTPase5 36 deegkprvvlvlGpaGeGKttaLmqvavelaaakg 70 ++ ++p+vvl++G+ G GKtt +++a+++a+++g FUN_000600-T1 492 EDCRRPKVVLIEGEPGMGKTTYCRKLAYDWATTQG 526 56689**************************6655 PP == domain 2 score: 0.7 bits; conditional E-value: 0.6 nSTAND_NTPase5 90 lelkekekwllvvDdadlvadelakllkk.lekegrk.vlvllaeRdn 135 l+ k +k+llv+D d e +l+ k ++ke+ + ++l++R+ FUN_000600-T1 576 LS-KNPSKVLLVLDGLDEADPEKLTLFCKlVQKEKLPgCFIVLTSRHE 622 33.368999****99998766655555551666666699******997 PP >> RESC10 RNA-editing substrate-binding complex 10 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.0 0.0 0.0095 9.7 335 358 .. 1064 1087 .. 1027 1098 .. 0.86 2 ? 4.5 0.1 0.014 15 301 358 .. 1113 1171 .. 1106 1177 .. 0.78 3 ! 7.4 0.1 0.0018 1.9 289 358 .. 1132 1199 .. 1121 1203 .. 0.76 4 ! 7.5 0.1 0.0017 1.8 302 358 .. 1170 1227 .. 1168 1239 .. 0.76 5 ? 3.8 0.0 0.023 23 335 358 .. 1204 1227 .. 1198 1258 .. 0.81 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0095 RESC10 335 ataalvsirlcyarvsdggrnaln 358 ++++l s++lcy+ +sd g n+l FUN_000600-T1 1064 VNTSLTSLNLCYNCISDEGANSLS 1087 7889*****************985 PP == domain 2 score: 4.5 bits; conditional E-value: 0.014 RESC10 301 tlssvlr.kfsllrlevcerlverivtadelthhm.ataalvsirlcyarvsdggrnaln 358 +ls+ lr + sl l++c++ + a++l++ + ++++l s++lc++ + d g n+l FUN_000600-T1 1113 ALSQALRvNTSLTSLNLCQNHIGDE-GANSLSQALrVNSSLTSLNLCHNTIGDEGANSLS 1171 6788888335677899999988775.56677776538999***************99985 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0018 RESC10 289 nhvsdltphecatlssvlrkf.sllrlevcerlverivtadelthhm.ataalvsirlcyarvsdggrnaln 358 nh++d +ls+ lr sl l++c + + a++l++ + ++++l s++lc +r+ d g n+l FUN_000600-T1 1132 NHIGDE---GANSLSQALRVNsSLTSLNLCHNTIGDE-GANSLSQALrVNTSLTSLNLCQNRIGDEGANSLS 1199 566553...345799999976156689***9999875.56777776538899***************99985 PP == domain 4 score: 7.5 bits; conditional E-value: 0.0017 RESC10 302 lssvlr.kfsllrlevcerlverivtadelthhm.ataalvsirlcyarvsdggrnaln 358 ls+ lr + sl l++c++ + a++l++ + ++++l s++lcy+ + d g n+l FUN_000600-T1 1170 LSQALRvNTSLTSLNLCQNRIGDE-GANSLSQALrVNSSLTSLNLCYNTIGDEGANSLS 1227 677777334566788888777654.56777776548999****************9985 PP == domain 5 score: 3.8 bits; conditional E-value: 0.023 RESC10 335 ataalvsirlcyarvsdggrnaln 358 ++++l s++lcy+ + d g n+l FUN_000600-T1 1204 VNSSLTSLNLCYNTIGDEGANSLS 1227 688999999999999999999874 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 3.7 0.00096 0.98 22 61 .] 951 994 .. 926 994 .. 0.76 2 ! 10.5 5.6 0.00053 0.55 2 61 .] 955 1022 .. 954 1022 .. 0.77 3 ! 7.7 0.9 0.0041 4.2 2 37 .. 1011 1050 .. 1010 1052 .. 0.60 4 ! 9.4 3.8 0.0012 1.3 2 58 .. 1039 1103 .. 1038 1106 .. 0.71 5 ? 6.4 7.5 0.011 11 2 61 .] 1123 1190 .. 1122 1190 .. 0.75 6 ? 6.2 7.3 0.012 12 2 59 .. 1179 1244 .. 1178 1246 .. 0.74 7 ? 5.7 3.2 0.018 18 2 38 .. 1207 1247 .. 1206 1271 .. 0.70 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00096 LRR_8 22 kglsnLkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgNrL 61 k +++L++L+Ls N++ ++ls +a++g +sL+sLdL++N + FUN_000600-T1 951 KVNTSLTSLYLSFNSIgdegaNSLS-QALRGNTSLTSLDLTRNSI 994 4468999999999999666666786.9999999999999999976 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00053 LRR_8 2 nLrsLdLssNrltsldd....gaFkglsnLkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgNrL 61 +L+sL+Ls+N++ + + +a +g+++L++LdL++N++ + ls +a++ +sL+sLdL++N + FUN_000600-T1 955 SLTSLYLSFNSIGDEGAnslsQALRGNTSLTSLDLTRNSIgdegiKALS-QALRVNTSLTSLDLTRNSI 1022 7999999999998776522225678999***********6333336786.9999999*******99986 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0041 LRR_8 2 nLrsLdLssNrltslddgaFkg....lsnLkvLdLsnNll 37 +L+sLdL++N++ + + +a + +++L++LdL++N++ FUN_000600-T1 1011 SLTSLDLTRNSIGDEGVKALSQalrvNTSLTSLDLTRNSI 1050 6777777777776655555444311246777777777776 PP == domain 4 score: 9.4 bits; conditional E-value: 0.0012 LRR_8 2 nLrsLdLssNrltslddgaFkg....lsnLkvLdLsnNllttlspgafsg....LpsLrsLdLsg 58 +L+sLdL++N++ + + +a + +++L++L+L +N+++ ++++s+ +sL+sLdL + FUN_000600-T1 1039 SLTSLDLTRNSIGDEGVKALSQalrvNTSLTSLNLCYNCISDEGANSLSQtlrvNTSLTSLDLKR 1103 89**********9877777665422268************9766655554222257777777765 PP == domain 5 score: 6.4 bits; conditional E-value: 0.011 LRR_8 2 nLrsLdLssNrltslddgaFkg....lsnLkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgNrL 61 +L+sL+L+ N++ + + + + +s+L++L+L +N++ ++ls +a++ +sL+sL+L +Nr+ FUN_000600-T1 1123 SLTSLNLCQNHIGDEGANSLSQalrvNSSLTSLNLCHNTIgdegaNSLS-QALRVNTSLTSLNLCQNRI 1190 79*********98766554443211279************555555665.7777789999999999987 PP == domain 6 score: 6.2 bits; conditional E-value: 0.012 LRR_8 2 nLrsLdLssNrltslddgaFkg....lsnLkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgN 59 +L+sL+L+ Nr+ + + + + +s+L++L+L +N++ ++ls +a++ +sL+sL+L +N FUN_000600-T1 1179 SLTSLNLCQNRIGDEGANSLSQalrvNSSLTSLNLCYNTIgdegaNSLS-QALRVNTSLTSLNLCHN 1244 79**********8766554443211279***********9555545665.77777899999999998 PP == domain 7 score: 5.7 bits; conditional E-value: 0.018 LRR_8 2 nLrsLdLssNrltslddgaFkg....lsnLkvLdLsnNllt 38 +L+sL+L++N + + + + + +++L++L+L +N++ FUN_000600-T1 1207 SLTSLNLCYNTIGDEGANSLSQalrvNTSLTSLNLCHNCIG 1247 78888888888876555444332112689999999999985 PP >> AAA_25 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 1.2e-05 0.012 33 65 .. 497 531 .. 491 545 .. 0.83 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.2e-05 AAA_25 33 gelillaGapgtGKttlaldlalava..tGkpwlg 65 +++l+ G pg GKtt + la+++a +G+ w FUN_000600-T1 497 PKVVLIEGEPGMGKTTYCRKLAYDWAttQGRKWDK 531 57999*********************999**9964 PP >> KAP_NTPase KAP family P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.086 88 18 46 .. 495 523 .. 478 529 .. 0.80 2 ? 10.0 0.1 0.0005 0.51 124 172 .. 544 606 .. 509 607 .. 0.70 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.086 KAP_NTPase 18 apglvigltGkWGsGKssllnllekelne 46 +++ v+ ++G+ G+GK++ +l+ ++ + FUN_000600-T1 495 RRPKVVLIEGEPGMGKTTYCRKLAYDWAT 523 78899*************99999888766 PP == domain 2 score: 10.0 bits; conditional E-value: 0.0005 KAP_NTPase 124 a.............kslqkeve.ellkdiestlkdlnkrivviiDdLDRceqeeirelleavr 172 + l++++e e+++++++ l ++ +++++++D+LD +++e++++ ++v+ FUN_000600-T1 544 CreiessiweaideQILPEDIEpEVRDMFIQFLSKNPSKVLLVLDGLDEADPEKLTLFCKLVQ 606 14555566666666666777763677788899999********************99999886 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.00019 0.19 1 73 [. 500 597 .. 500 627 .. 0.68 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00019 AAA 1 lllyGppGtGKTllakavakelgae..............fveisgselvsk.........yvgesekklrelfeeakkka..psvifiDEiDalak 71 +l+ G pG+GKT+ ++ +a ++ ++ ++ + + e+ s+ + e ++r++f + +k+ + ++++D +D+ + FUN_000600-T1 500 VLIEGEPGMGKTTYCRKLAYDWATTqgrkwdksfprievLLLLRCREIESSiweaideqiLPEDIEPEVRDMFIQFLSKNpsKVLLVLDGLDEADP 595 6889****************9842223334444444444455555555544888888888888888999999988655553346777888887766 PP AAA 72 kr 73 ++ FUN_000600-T1 596 EK 597 55 PP >> RNA_helicase RNA helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00026 0.27 1 33 [. 500 532 .. 500 537 .. 0.86 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00026 RNA_helicase 1 iwlyGpsgeGKStlakelakallkklklpkkds 33 +++ G++g GK+t++++la +++++ + ++++s FUN_000600-T1 500 VLIEGEPGMGKTTYCRKLAYDWATTQGRKWDKS 532 6799******************98887777665 PP >> VapE-like_dom Virulence-associated protein E-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.00014 0.15 38 81 .. 482 526 .. 457 551 .. 0.80 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00014 VapE-like_dom 38 aaVarvfeP..GckfdtvlvLeGaqGigKstflekLagekwfsdsl 81 + ++ +f+P c+ v+ +eG+ G+gK+t ++kLa +w +++ FUN_000600-T1 482 NSMTSIFKPheDCRRPKVVLIEGEPGMGKTTYCRKLAY-DWATTQG 526 55667788866799999*********************.9998854 PP >> Zeta_toxin Zeta toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00018 0.19 11 38 .. 491 519 .. 482 527 .. 0.81 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00018 Zeta_toxin 11 psq.erPvavllaGqpGAGKtelaellke 38 +++ +rP++vl+ G pG GKt+ ++l+ FUN_000600-T1 491 HEDcRRPKVVLIEGEPGMGKTTYCRKLAY 519 56669*****************9998875 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00027 0.28 29 126 .. 491 588 .. 471 594 .. 0.77 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00027 TniB 29 apkkkrmpnlllvGdsnnGKstivekFarlhpaqk.eedeeevpvvvvqappepdekrlyaaiLeaLeapikardrlskleqqvlelLralkvrmL 123 +++ r++ +l+ G++ +GK+t ++k a + ++ ++ ++ p + v + ++ +++ ++i ea+ +i +d + +++ +++L++ ++L FUN_000600-T1 491 HEDCRRPKVVLIEGEPGMGKTTYCRKLAYDWATTQgRKWDKSFPRIEVLLLLRC--REIESSIWEAIDEQILPEDIEPEVRDMFIQFLSKNPSKVL 584 3446677889999*************9977766652444555677777777777..788999999999999999*999*******99999999986 PP TniB 124 i.iD 126 + +D FUN_000600-T1 585 LvLD 588 5155 PP >> ATPase KaiC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00043 0.44 17 48 .. 495 526 .. 480 529 .. 0.84 2 ? -3.5 0.1 7.2 7.4e+03 35 87 .. 800 852 .. 799 858 .. 0.80 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00043 ATPase 17 pegrvvlisGepGtGKtifglqFlingaekyg 48 + +vvli GepG GKt+ + + ++ a + g FUN_000600-T1 495 RRPKVVLIEGEPGMGKTTYCRKLAYDWATTQG 526 56789***************999998877766 PP == domain 2 score: -3.5 bits; conditional E-value: 7.2 ATPase 35 fglqFlingaekygepgvfvtleetaedlrenakslGwdlekleeegklaiid 87 f++ Fl ++ + ++ ++ v+ e+ ++l + ++ +G + e + i++ FUN_000600-T1 800 FSAFFLAFSIIDGDRDCMSVANREHGRKLSQVFTFMGGMVAMHSEATTFSIVK 852 77889999999989999999999999999999999987777777776777665 PP >> OmcA-like_N OmcA-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.097 99 82 125 .. 1052 1095 .. 999 1102 .. 0.81 2 ? -0.6 0.0 1.4 1.5e+03 41 123 .. 1124 1205 .. 1110 1220 .. 0.66 3 ? 5.5 0.1 0.019 20 46 125 .. 1185 1263 .. 1166 1270 .. 0.76 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.097 OmcA-like_N 82 pedeidlnpsaqfqaeveaaskcdtclvdngdGsysytfqvnia 125 +e+ l++ +++ + + c +c+ d+g s s t +vn + FUN_000600-T1 1052 DEGVKALSQALRVNTSLTSLNLCYNCISDEGANSLSQTLRVNTS 1095 444455667777888889999*******************9975 PP == domain 2 score: -0.6 bits; conditional E-value: 1.4 OmcA-like_N 41 iaqltevtetvgeddeavevdrGyqwqayinsekePneayapedeidlnpsaqfqaeveaaskcdtclvdngdGsysytfqvn 123 ++ l ++ +g+ + a + + + + + s + ++ +e+ l++ +++ + + c++ + d+g s s + +vn FUN_000600-T1 1124 LTSLNLCQNHIGD-EGANSLSQALRVNSSLTSLNLCHNTIGDEGANSLSQALRVNTSLTSLNLCQNRIGDEGANSLSQALRVN 1205 5555555666665.456666666666666666666667777777777777777777777777888888888777777777776 PP == domain 3 score: 5.5 bits; conditional E-value: 0.019 OmcA-like_N 46 evtetvgeddeavevdrGyqwqayinsekePneayapedeidlnpsaqfqaeveaaskcdtclvdngdGsysytfqvnia 125 ++ +g+ + a + + + + + s + ++ +e+ l++ +++ + + c++c+ d+g s s t +vn + FUN_000600-T1 1185 LCQNRIGD-EGANSLSQALRVNSSLTSLNLCYNTIGDEGANSLSQALRVNTSLTSLNLCHNCIGDEGANSLSQTLRVNTS 1263 55556665.4566666666666667777777777777887888888999999999*********************9975 PP >> P2X_receptor ATP P2X receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.1 0.00032 0.33 291 359 .. 821 890 .. 816 892 .. 0.82 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00032 P2X_receptor 291 ngtekRtLiKaygir.fdilvkgkagkFdiiptlinigsglallgvatvlcdlilltllkkaefYkekkf 359 n ++ R+L ++++ ++++++a F+i++t+++i+ +l+ ++++ + + l ++++ ++++e+ + FUN_000600-T1 821 NREHGRKLSQVFTFMgGMVAMHSEATTFSIVKTIVSIVNALGHVSLGYRIPLSLALRFISECKLFSETLY 890 6677899999998651467899************************998888888888888777777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1274 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 742 (0.0290468); expected 510.9 (0.02) Passed bias filter: 643 (0.0251713); expected 510.9 (0.02) Passed Vit filter: 96 (0.00375807); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 25 [number of targets reported over threshold] # CPU time: 0.53u 0.41s 00:00:00.94 Elapsed: 00:00:00.43 # Mc/sec: 11918.08 // Query: FUN_000601-T1 [L=92] Description: FUN_000601 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (92 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 672 (0.0263065); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 922.72 // Query: FUN_000602-T1 [L=735] Description: FUN_000602 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-84 284.1 0.0 2.9e-84 283.8 0.0 1.1 1 GT4-conflict Family 4 Glycosyltransferase in conflict sys 3.6e-28 95.8 27.4 1.3e-05 25.3 0.3 7.5 8 LRR_6 Leucine Rich repeat 9.7e-19 68.5 0.0 2.8e-18 67.0 0.0 1.8 2 Glyco_trans_1_4 Glycosyl transferases group 1 1.5e-17 64.1 0.0 3e-17 63.2 0.0 1.4 1 Glycos_transf_1 Glycosyl transferases group 1 2.8e-08 32.8 10.5 6.9 7.8 0.1 6.6 7 LRR_1 Leucine Rich Repeat 0.0076 17.0 17.9 0.28 12.0 0.7 4.7 5 LRR_4 Leucine Rich repeats (2 copies) ------ inclusion threshold ------ 0.44 10.8 18.4 2.5 8.4 6.2 4.5 4 LRR_8 Leucine rich repeat Domain annotation for each model (and alignments): >> GT4-conflict Family 4 Glycosyltransferase in conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 283.8 0.0 8e-88 2.9e-84 2 385 .] 19 384 .. 18 384 .. 0.93 Alignments for each domain: == domain 1 score: 283.8 bits; conditional E-value: 8e-88 GT4-conflict 2 vvatewssakGGistfNreLceaLAaaga.eviclVpeaseeeiadAkaagVrLvkaeaepgvsereslllrrpelpagvepdlviGHgrvtGpaA 96 ++a ew+s+kGG+st+NreL++ LA+ + ev+ + s+e+ ++A+++g+ +v+a+++pg +e l+ p+ +++ d+viGHg G+ A FUN_000602-T1 19 ILASEWGSSKGGLSTINRELAIQLAKYYDcEVTFFLIKCSHENKEEARRHGISIVEADRKPGYEELD-WLSFPPQ---DLQIDIVIGHGVKLGKQA 110 5799***********************555***********************************99.5555544...6788************** PP GT4-conflict 97 kalaedfypdakrvhfvHmapdelewlkekrdaaeraeerekierelaakAdlvvaVGprLaeearrllseapgepkvleldpgfdveaeeeprtp 192 +++++ + ++k v++vH++p++l ++k +++ ++e+++ +e+el++ Adlvv+VGp+L+e +r+ l+++++++ v e++p + +++++ +++ FUN_000602-T1 111 QVIRNYH--KCKWVQVVHTDPEKLGMFKCYENPISKGEQKHHVEVELCQMADLVVGVGPMLTEAFRKYLRGCKKDQGVFEFTPSVFTDFASVEQAL 204 ****998..*****************************************************************************9999878888 PP GT4-conflict 193 peggklkvLllGRae..DaelKgldlAaravgrlakesrderveLvvrGapaeeaeelrerlaeiagepalevtvrpytkdraeleadlrraslvl 286 e++ ++vL++GR + D elKg d+Aar v++l + +Lv +Gap+ + +e ++rl ++ g p+ ++tvr ++ dr++l++ + + +l+l FUN_000602-T1 205 DERKVHSVLVFGRGDneDFELKGFDIAARSVAALPD------THLVFVGAPDRKEQEIAKRLLDL-GIPKGRLTVRGFK-DREALKQLFCEVDLLL 292 89***********9989**************88865......79********************6.9999********5.899************* PP GT4-conflict 287 mPSraEGFGLvglEAiaagvPvLvsseSGlaelLeek.lseeeaerlvvpvtgddeedaeewaraieevlr.dleaaferaaelreeLaerltWaa 380 mPSr+EGFGL+glEA++ag+Pv+vs++SG++e L++ +++ ++v++ ++d+ +w++ai+++++ d++++ +++++lr+ +r++W+ FUN_000602-T1 293 MPSRTEGFGLTGLEALSAGLPVVVSKNSGFGEALSSVpFGP----SFVID-SEDP----TAWTAAIKSIWDkDRQTRLDETKHLRDSYGKRYSWSG 379 **********************************9994444....47777.4444....7**********64899999*****************9 PP GT4-conflict 381 aaasL 385 +++L FUN_000602-T1 380 QCENL 384 98876 PP >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 4.4 1.6e+04 16 24 .] 301 309 .. 299 309 .. 0.79 2 ? 2.3 0.1 0.083 3e+02 1 11 [. 555 565 .. 555 566 .. 0.87 3 ! 23.7 0.1 1.2e-08 4.4e-05 2 21 .. 586 605 .. 585 607 .. 0.90 4 ! 25.3 0.3 3.6e-09 1.3e-05 1 23 [. 613 635 .. 613 636 .. 0.92 5 ! 25.3 0.3 3.6e-09 1.3e-05 1 23 [. 641 663 .. 641 664 .. 0.92 6 ! 18.5 0.0 5.8e-07 0.0021 1 24 [] 669 692 .. 669 692 .. 0.94 7 ! 16.0 0.1 3.5e-06 0.013 1 21 [. 697 717 .. 697 719 .. 0.90 8 ? 0.1 0.1 0.44 1.6e+03 1 10 [. 725 734 .. 725 735 .] 0.90 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 4.4 LRR_6 16 gDeGleaLa 24 g +GleaL+ FUN_000602-T1 301 GLTGLEALS 309 678****96 PP == domain 2 score: 2.3 bits; conditional E-value: 0.083 LRR_6 1 hnttLteLdLs 11 +nt+Lt+L L FUN_000602-T1 555 VNTSLTSLSLF 565 59******996 PP == domain 3 score: 23.7 bits; conditional E-value: 1.2e-08 LRR_6 2 nttLteLdLsgNdIgDeGle 21 n +Lt+LdL++N+IgD+G+ FUN_000602-T1 586 NASLTSLDLRYNEIGDKGAN 605 99****************95 PP == domain 4 score: 25.3 bits; conditional E-value: 3.6e-09 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt Lt+LdLs+N IgD+G+ +L FUN_000602-T1 613 VNTFLTSLDLSFNSIGDDGANSL 635 59*****************9777 PP == domain 5 score: 25.3 bits; conditional E-value: 3.6e-09 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt Lt+LdLs+N IgD+G+ +L FUN_000602-T1 641 VNTFLTSLDLSFNSIGDDGANSL 663 59*****************9777 PP == domain 6 score: 18.5 bits; conditional E-value: 5.8e-07 LRR_6 1 hnttLteLdLsgNdIgDeGleaLa 24 +n++Lt+LdLs N Ig +G+ +L+ FUN_000602-T1 669 VNSSLTSLDLSRNFIGTKGAYSLS 692 599*****************9985 PP == domain 7 score: 16.0 bits; conditional E-value: 3.5e-06 LRR_6 1 hnttLteLdLsgNdIgDeGle 21 +nt+Lt+L+L +N Ig eG+ FUN_000602-T1 697 VNTSLTSLNLFFNSIGWEGAN 717 59**************99985 PP == domain 8 score: 0.1 bits; conditional E-value: 0.44 LRR_6 1 hnttLteLdL 10 +nt+ t+L+L FUN_000602-T1 725 VNTSFTSLNL 734 59*******9 PP >> Glyco_trans_1_4 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 3.7 1.3e+04 37 70 .. 161 198 .. 158 205 .. 0.63 2 ! 67.0 0.0 7.8e-22 2.8e-18 4 139 .. 212 353 .. 209 355 .. 0.85 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 3.7 Glyco_trans_1_4 37 vivGdgpeeeeeleelak..gledr.veftGfv.edla 70 ++vG gp+ e++++ ++ + +++ +eft v +d a FUN_000602-T1 161 LVVGVGPMLTEAFRKYLRgcKKDQGvFEFTPSVfTDFA 198 57888886666787766633223345788887776644 PP == domain 2 score: 67.0 bits; conditional E-value: 7.8e-22 Glyco_trans_1_4 4 ilfvGrl.ae..nekgvdllleavplvrkkerdvrlvivGdgpeeeeeleelak..gledr.veftGfv..edlaellaaadvfvlPslsegfg 89 +l +Gr +e + kg+d+ ++ v+++ + ++lv+vG +++e+e+ +++ g+ ++ ++ Gf e l++l+ + d++++Ps++egfg FUN_000602-T1 212 VLVFGRGdNEdfELKGFDIAARSVAALP--D--THLVFVGAPDRKEQEIAKRLLdlGIPKGrLTVRGFKdrEALKQLFCEVDLLLMPSRTEGFG 301 6777877655778899999999999999..3..7******6666667887766448887667*******8666********************* PP Glyco_trans_1_4 90 lkllEAmaaglPvVatdvggipevvedgeng..llvppgdpealaeailrll 139 l+ lEA++aglPvV+++ +g+ e++ g ++++++dp+a+ +ai +++ FUN_000602-T1 302 LTGLEALSAGLPVVVSKNSGFGEALSSVPFGpsFVIDSEDPTAWTAAIKSIW 353 ******************9****9977655566***************9876 PP >> Glycos_transf_1 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.2 0.0 8.3e-21 3e-17 28 159 .. 226 356 .. 212 368 .. 0.84 Alignments for each domain: == domain 1 score: 63.2 bits; conditional E-value: 8.3e-21 Glycos_transf_1 28 KgldlllkafaklkeklkpdlklviaG..dgeeekklkklaeklgl.ednvkflgfvsdedlpellkiadvfvlpsrsEgfGivllEAmaaglp 118 Kg+d + +++a pd++lv++G d +e++ k+l + lg+ + ++++ gf+++e+l++l+ d++++psr+EgfG++ lEA++aglp FUN_000602-T1 226 KGFDIAARSVAA-----LPDTHLVFVGapDRKEQEIAKRL-LDLGIpKGRLTVRGFKDREALKQLFCEVDLLLMPSRTEGFGLTGLEALSAGLP 313 666666666665.....59********7655555555555.666652679******************************************** PP Glycos_transf_1 119 viasdvgglrevvkdge..tGllvkpnnaealaeaiekllede 159 v++s+++g+ e + + ++++++++ a+ +ai+++ +++ FUN_000602-T1 314 VVVSKNSGFGEALSSVPfgPSFVIDSEDPTAWTAAIKSIWDKD 356 *************98766688****************998765 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 3.7 1.4e+04 3 18 .. 525 540 .. 525 543 .. 0.70 2 ? -3.6 0.0 7 2.6e+04 1 9 [. 558 566 .. 558 571 .. 0.78 3 ! 7.1 0.0 0.0033 12 1 20 [. 588 607 .. 588 610 .. 0.85 4 ! 7.8 0.1 0.0019 6.9 2 21 .. 617 636 .. 616 638 .. 0.83 5 ! 7.6 0.1 0.0023 8.4 2 20 .. 645 663 .. 644 666 .. 0.82 6 ! 7.1 0.0 0.0032 12 1 17 [. 672 688 .. 672 693 .. 0.80 7 ? 4.4 0.1 0.027 98 1 19 [. 700 718 .. 700 721 .. 0.81 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 3.7 LRR_1 3 eeLdLsnNnlsgllpe 18 ++LdL++ l+ ++ + FUN_000602-T1 525 RTLDLDDMTLEPEPED 540 68***99999644444 PP == domain 2 score: -3.6 bits; conditional E-value: 7 LRR_1 1 nLeeLdLsn 9 +L++L+L + FUN_000602-T1 558 SLTSLSLFG 566 699999865 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0033 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L++LdL++N ++++ +sl FUN_000602-T1 588 SLTSLDLRYNEIGDKGANSL 607 79**********88877776 PP == domain 4 score: 7.8 bits; conditional E-value: 0.0019 LRR_1 2 LeeLdLsnNnlsgllpeslg 21 L++LdLs N++++ +sl+ FUN_000602-T1 617 LTSLDLSFNSIGDDGANSLS 636 99*********887777765 PP == domain 5 score: 7.6 bits; conditional E-value: 0.0023 LRR_1 2 LeeLdLsnNnlsgllpesl 20 L++LdLs N++++ +sl FUN_000602-T1 645 LTSLDLSFNSIGDDGANSL 663 99*********87776666 PP == domain 6 score: 7.1 bits; conditional E-value: 0.0032 LRR_1 1 nLeeLdLsnNnlsgllp 17 +L++LdLs+N ++++ FUN_000602-T1 672 SLTSLDLSRNFIGTKGA 688 79*********976655 PP == domain 7 score: 4.4 bits; conditional E-value: 0.027 LRR_1 1 nLeeLdLsnNnlsgllpes 19 +L++L+L N+++ + +s FUN_000602-T1 700 SLTSLNLFFNSIGWEGANS 718 79**********7766655 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.1 0.92 3.3e+03 10 18 .. 556 564 .. 545 568 .. 0.54 2 ! 10.0 0.6 0.00032 1.2 2 37 .. 588 628 .. 587 634 .. 0.71 3 ! 11.2 1.3 0.00013 0.49 3 38 .. 617 657 .. 615 664 .. 0.78 4 ! 12.0 0.7 7.7e-05 0.28 3 36 .. 645 683 .. 643 689 .. 0.81 5 ! 8.5 1.9 0.00096 3.5 2 36 .. 672 711 .. 671 715 .. 0.78 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.92 LRR_4 10 nNritdidp 18 n+++t++++ FUN_000602-T1 556 NTSLTSLSL 564 445555544 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00032 LRR_4 2 nLetLdLsnNritdidp....ls...k.LpnLetLdLsgNnkit 37 +L++LdL++N i d l + L++LdLs N i FUN_000602-T1 588 SLTSLDLRYNEIGD--KgansLTqalRvNTFLTSLDLSFN-SIG 628 79***********6..332453344433777******777.665 PP == domain 3 score: 11.2 bits; conditional E-value: 0.00013 LRR_4 3 LetLdLsnNritdidp..ls...k.LpnLetLdLsgNnkitd 38 L++LdLs N+i d + ls + L++LdLs N i d FUN_000602-T1 617 LTSLDLSFNSIGDDGAnsLSqalRvNTFLTSLDLSFN-SIGD 657 99**********7555685566644999******777.6654 PP == domain 4 score: 12.0 bits; conditional E-value: 7.7e-05 LRR_4 3 LetLdLsnNritdidp..ls...k.LpnLetLdLsgNnki 36 L++LdLs N+i d + ls +L++LdLs+N i FUN_000602-T1 645 LTSLDLSFNSIGDDGAnsLSealRvNSSLTSLDLSRN-FI 683 99**********7555685567754999******888.66 PP == domain 5 score: 8.5 bits; conditional E-value: 0.00096 LRR_4 2 nLetLdLsnNrit.didp...ls...k.LpnLetLdLsgNnki 36 +L++LdLs N i + + ls k ++L++L+L n i FUN_000602-T1 672 SLTSLDLSRNFIGtK--GaysLSealKvNTSLTSLNL-FFNSI 711 89*******9**944..45575578988*********.54444 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 1 3.7e+03 5 39 .. 526 561 .. 525 565 .. 0.57 2 ? 6.3 0.9 0.003 11 24 60 .. 586 626 .. 577 627 .. 0.66 3 ? 6.4 5.5 0.003 11 3 59 .. 617 681 .. 615 683 .. 0.68 4 ? 8.4 6.2 0.00069 2.5 3 61 .] 645 711 .. 643 711 .. 0.75 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1 LRR_8 5 sLdLssNrltslddgaFkglsnLkvLdLsnN.lltt 39 +LdL++ l+ + ++F+ + L L+ N +lt+ FUN_000602-T1 526 TLDLDDMTLEPEPEDWFEASLSTLFLALRVNtSLTS 561 677777777777778888544444444444445554 PP == domain 2 score: 6.3 bits; conditional E-value: 0.003 LRR_8 24 lsnLkvLdLsnNllttlspgafsg....LpsLrsLdLsgNr 60 + +L++LdL++N++ ++++ + + L+sLdLs N FUN_000602-T1 586 NASLTSLDLRYNEIGDKGANSLTQalrvNTFLTSLDLSFNS 626 67899999999999777666655411114557777777776 PP == domain 3 score: 6.4 bits; conditional E-value: 0.003 LRR_8 3 LrsLdLssNrltslddgaFkg.lsn...LkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgN 59 L+sLdLs+N++ + + + + l+ L++LdLs N++ ++ls +a++ +sL+sLdLs+N FUN_000602-T1 617 LTSLDLSFNSIGDDGANSLSQaLRVntfLTSLDLSFNSIgddgaNSLS-EALRVNSSLTSLDLSRN 681 788899999888888877766332233388999999999333333444.55666789999999988 PP == domain 4 score: 8.4 bits; conditional E-value: 0.00069 LRR_8 3 LrsLdLssNrltslddgaFkg....lsnLkvLdLsnNllttlspgafsg....LpsLrsLdLsgNrL 61 L+sLdLs+N++ + + + + +s+L++LdLs+N + t + ++s +sL+sL+L N + FUN_000602-T1 645 LTSLDLSFNSIGDDGANSLSEalrvNSSLTSLDLSRNFIGTKGAYSLSEalkvNTSLTSLNLFFNSI 711 899********9999765543311289************9977655554222279999999999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (735 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 596 (0.0233314); expected 510.9 (0.02) Passed bias filter: 550 (0.0215306); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7067.19 // Query: FUN_000603-T1 [L=773] Description: FUN_000603 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-29 98.4 24.6 1.9e-05 24.8 0.9 6.7 6 LRR_6 Leucine Rich repeat 2.6e-24 86.4 0.0 4.8e-24 85.5 0.0 1.5 1 NACHT NACHT domain 5e-09 37.4 0.0 2.2e-08 35.3 0.0 2.1 1 AAA_16 AAA ATPase domain 1.3e-06 29.2 0.0 0.011 16.4 0.0 2.8 2 NPHP3_N Nephrocystin 3, N-terminal 7e-06 26.6 11.3 0.02 15.6 1.9 4.3 3 LRR_4 Leucine Rich repeats (2 copies) 7.7e-06 25.5 14.8 1.9 9.5 0.2 7.4 6 LRR_1 Leucine Rich Repeat 3.8e-05 23.9 0.0 0.00014 22.0 0.0 2.0 1 nSTAND3 Novel STAND NTPase 3 9.5e-05 22.7 0.0 0.00041 20.7 0.0 2.0 2 nSTAND_NTPase5 Novel STAND NTPase 5 0.00011 22.3 0.0 0.00021 21.4 0.0 1.4 1 NB-ARC NB-ARC domain 0.0012 19.6 0.0 0.0039 18.0 0.0 1.9 1 AAA_22 AAA domain 0.0043 17.2 0.0 0.0082 16.3 0.0 1.4 1 AAA_25 AAA domain ------ inclusion threshold ------ 0.047 13.6 0.0 0.08 12.9 0.0 1.3 1 VapE-like_dom Virulence-associated protein E-like domain 0.056 13.4 0.0 0.1 12.5 0.0 1.3 1 Zeta_toxin Zeta toxin 0.058 14.4 0.0 0.23 12.5 0.0 2.0 1 RNA_helicase RNA helicase 0.11 12.5 0.0 0.26 11.2 0.0 1.6 2 TniB Bacterial TniB protein 0.11 13.4 0.0 0.28 12.1 0.0 1.7 1 AAA ATPase family associated with various cellu 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 ATPase KaiC 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 SRP54 SRP54-type protein, GTPase domain 0.18 11.5 0.0 1.1 8.9 0.0 2.0 2 SLFN-g3_helicase Schlafen group 3, DNA/RNA helicase domain 0.18 12.2 0.0 0.45 11.0 0.0 1.6 1 TsaE Threonylcarbamoyl adenosine biosynthesis pr 0.61 10.7 1.5 1.2 9.8 0.2 2.1 2 SF3A3 Pre-mRNA-splicing factor SF3A3, of SF3a com 0.63 10.3 18.3 9.2 6.6 7.2 4.6 4 LRR_8 Leucine rich repeat Domain annotation for each model (and alignments): >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.1 0.013 16 2 23 .. 599 620 .. 598 621 .. 0.91 2 ! 18.0 0.0 2.6e-06 0.003 1 23 [. 626 648 .. 626 649 .. 0.91 3 ! 24.2 0.7 2.6e-08 3.1e-05 1 23 [. 654 676 .. 654 677 .. 0.92 4 ! 24.8 0.9 1.7e-08 1.9e-05 1 23 [. 682 704 .. 682 705 .. 0.92 5 ! 22.0 0.3 1.4e-07 0.00016 1 23 [. 710 732 .. 710 733 .. 0.92 6 ! 16.9 0.3 5.5e-06 0.0064 1 21 [. 738 758 .. 738 760 .. 0.91 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.013 LRR_6 2 nttLteLdLsgNdIgDeGleaL 23 n++Lt+L L IgDeG+ +L FUN_000603-T1 599 NSSLTSLRLCRSYIGDEGANSL 620 899***************9777 PP == domain 2 score: 18.0 bits; conditional E-value: 2.6e-06 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L Ls+N Ig +G+ L FUN_000603-T1 626 ANTSLTSLVLSYNSIGYKGADFL 648 59*****************9876 PP == domain 3 score: 24.2 bits; conditional E-value: 2.6e-08 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nttLt+L Ls+N IgDeG+ +L FUN_000603-T1 654 TNTTLTSLVLSDNSIGDEGANSL 676 59*****************9777 PP == domain 4 score: 24.8 bits; conditional E-value: 1.7e-08 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nt+Lt+L+Ls+N IgD+G+ +L FUN_000603-T1 682 VNTSLTSLNLSSNSIGDKGANSL 704 59*****************9777 PP == domain 5 score: 22.0 bits; conditional E-value: 1.4e-07 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +nttLt+L L +N IgDeG+ +L FUN_000603-T1 710 ANTTLTSLVLFDNSIGDEGANSL 732 59*****************9777 PP == domain 6 score: 16.9 bits; conditional E-value: 5.5e-06 LRR_6 1 hnttLteLdLsgNdIgDeGle 21 +nttLt+L Ls+N Ig eG+ FUN_000603-T1 738 ANTTLTSLVLSDNSIGREGVN 758 59*****************85 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.5 0.0 4.1e-27 4.8e-24 2 166 .. 145 301 .. 144 302 .. 0.92 Alignments for each domain: == domain 1 score: 85.5 bits; conditional E-value: 4.1e-27 NACHT 2 tvilqGeaGsGKTtLlqklalawaegklpqda.....fklvFflslrelsrsgkalsladllfsqlpepaapvseviavllelperlLlilDGlDe 92 +v+++Ge+G+GKTt +kla +wa+++ +++++l++re++ s + +++++ q+ ep+ + +i++l e+p ++Ll lDGlDe FUN_000603-T1 145 VVLIEGEPGMGKTTYCRKLAYDWATRQGRTWDksfprIEVLLLLRCREIESSIWE-AIDEQILPQGIEPEVRDV-FIQFLRENPSKVLLMLDGLDE 238 89**********************9987664445666899***********9877.*************99885.59******************* PP NACHT 93 lksqlgqpkekqpvrtlLssllrkkllpeasllltvrpdalrklregleeaavlevegfseedrkeyvrkyfsd 166 ++ ++ tl+ +l++k+ lp+++++lt+r +a +++r + le+ gf++ d+++++rkyf++ FUN_000603-T1 239 ADP--EK-------LTLFCTLVQKEELPGCFIVLTSRHEAGSNIRPFTDTL--LEIVGFTRTDAECFIRKYFQQ 301 *97..33.......68*****************************999999..*******************86 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.3 0.0 1.9e-11 2.2e-08 23 168 .. 142 261 .. 125 262 .. 0.70 Alignments for each domain: == domain 1 score: 35.3 bits; conditional E-value: 1.9e-11 AAA_16 23 rpplvlvsGeaGvGKSalvrellraleraalvlsgkcdelqrglpyaallealtresllrqllaeseaallaawraalleelaavpalegeeaerl 118 rp +vl+ Ge+G+GK++ +r+l+ +++ +d + + + ll ++e e++ +a ++++l + + + FUN_000603-T1 142 RPKVVLIEGEPGMGKTTYCRKLAYDWATR---QGRTWDKS---F------PRI-E-VLLLLRCREIESSIWEAIDEQILPQGI---------EPEV 214 6799*******************877666...33444444...2......333.2.444445555444454444444333222.........2679 PP AAA_16 119 lealsrll.alaarkerplvlvlDdlqwadeasldllaaLlrlleskpllv 168 +++++++l ++ ++ ++l lD+l++ad++ l+l+++L++ e++ ++ FUN_000603-T1 215 RDVFIQFLrENP---SK-VLLMLDGLDEADPEKLTLFCTLVQKEELPGCFI 261 ********3333...34.************************999866555 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.0 0.0011 1.3 20 45 .. 141 166 .. 134 179 .. 0.80 2 ! 16.4 0.0 9.8e-06 0.011 82 164 .] 189 266 .. 176 266 .. 0.74 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.0011 NPHP3_N 20 sdssllwlsGkpGsGKsvlastvidh 45 ++++++ + G+pG+GK++ ++ ++ + FUN_000603-T1 141 KRPKVVLIEGEPGMGKTTYCRKLAYD 166 4578999*************998755 PP == domain 2 score: 16.4 bits; conditional E-value: 9.8e-06 NPHP3_N 82 qlpelreelleklaedlgldekdlrelweklletlllakslsrpvyiviDALDEceeseellellaellsksk.sklkvlvtSR 164 + +e+ ++++e+++e+ + + ++ +++++ ++l ++++++v +++D+LDE + ++ l+l+++l++k++ + + +++tSR FUN_000603-T1 189 RCREIESSIWEAIDEQ--ILPQGIEPEVRDVFIQFL--RENPSKVLLMLDGLDEADPEK--LTLFCTLVQKEElPGCFIVLTSR 266 4566777777777765..456678888899998776..578999***********9876..44555555555416799999999 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.036 42 3 38 .. 602 639 .. 600 647 .. 0.61 2 ! 15.6 1.9 1.7e-05 0.02 1 36 [. 656 696 .. 656 702 .. 0.84 3 ! 9.4 0.4 0.0016 1.8 1 38 [. 712 751 .. 712 758 .. 0.82 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.036 LRR_4 3 LetLdLsnNritdidp......lskLpnLetLdLsgNnkitd 38 L++L L i d + l+ ++L++L Ls N + FUN_000603-T1 602 LTSLRLCRSYIGDEGAnslsqaLRANTSLTSLVLSYN----S 639 5566666545555555553223446888888888777....3 PP == domain 2 score: 15.6 bits; conditional E-value: 1.7e-05 LRR_4 1 pnLetLdLsnNritdidp..ls...k.LpnLetLdLsgNnki 36 + L++L Ls+N+i d + ls ++L++L+Ls+N i FUN_000603-T1 656 TTLTSLVLSDNSIGDEGAnsLSqalRvNTSLTSLNLSSN-SI 696 68*************999995567744*********888.44 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0016 LRR_4 1 pnLetLdLsnNritdidp..ls....kLpnLetLdLsgNnkitd 38 + L++L L +N+i d + ls + L++L Ls+N + FUN_000603-T1 712 TTLTSLVLFDNSIGDEGAnsLSqalrANTTLTSLVLSDN----S 751 689************999995544436888******988....3 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.8 2.1e+03 1 21 [. 601 621 .. 601 623 .. 0.85 2 ? 5.1 0.0 0.047 54 1 19 [. 629 647 .. 629 651 .. 0.78 3 ? 6.2 0.0 0.02 23 2 21 .. 658 677 .. 657 679 .. 0.86 4 ! 9.5 0.2 0.0017 1.9 1 21 [. 685 705 .. 685 707 .. 0.87 5 ? 2.9 0.0 0.26 3e+02 2 21 .. 714 733 .. 713 735 .. 0.86 6 ? 4.9 0.1 0.057 66 2 19 .. 742 759 .. 741 762 .. 0.79 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.8 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L L++ ++++ +sl+ FUN_000603-T1 601 SLTSLRLCRSYIGDEGANSLS 621 79*********9888888776 PP == domain 2 score: 5.1 bits; conditional E-value: 0.047 LRR_1 1 nLeeLdLsnNnlsgllpes 19 +L++L Ls+N+++ + + FUN_000603-T1 629 SLTSLVLSYNSIGYKGADF 647 79**********7655555 PP == domain 3 score: 6.2 bits; conditional E-value: 0.02 LRR_1 2 LeeLdLsnNnlsgllpeslg 21 L++L Ls+N+++++ +sl+ FUN_000603-T1 658 LTSLVLSDNSIGDEGANSLS 677 99*********988888876 PP == domain 4 score: 9.5 bits; conditional E-value: 0.0017 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++L+Ls+N+++++ +sl+ FUN_000603-T1 685 SLTSLNLSSNSIGDKGANSLS 705 79**********988888876 PP == domain 5 score: 2.9 bits; conditional E-value: 0.26 LRR_1 2 LeeLdLsnNnlsgllpeslg 21 L++L L +N+++++ +sl+ FUN_000603-T1 714 LTSLVLFDNSIGDEGANSLS 733 99*********988888876 PP == domain 6 score: 4.9 bits; conditional E-value: 0.057 LRR_1 2 LeeLdLsnNnlsgllpes 19 L++L Ls+N+++ + +s FUN_000603-T1 742 LTSLVLSDNSIGREGVNS 759 99*********7665555 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 1.2e-07 0.00014 16 44 .. 142 170 .. 137 204 .. 0.84 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.2e-07 nSTAND3 16 knkvviitGepGiGKttlaemLalkllde 44 + kvv+i GepG+GKtt ++ La++++ + FUN_000603-T1 142 RPKVVLIEGEPGMGKTTYCRKLAYDWATR 170 569*********************99884 PP >> nSTAND_NTPase5 Novel STAND NTPase 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 3.5e-07 0.00041 21 72 .. 120 174 .. 111 176 .. 0.79 2 ? -2.1 0.0 3.8 4.4e+03 94 135 .. 225 268 .. 208 273 .. 0.68 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 3.5e-07 nSTAND_NTPase5 21 rrsivdelveell...ekdeegkprvvlvlGpaGeGKttaLmqvavelaaakgwt 72 +r++++e+ + ++ ++p+vvl++G+ G GKtt +++a+++a+++g+t FUN_000603-T1 120 CRTVTNEVTSMTGifaPHKDCKRPKVVLIEGEPGMGKTTYCRKLAYDWATRQGRT 174 56666666655555545567799**************************777765 PP == domain 2 score: -2.1 bits; conditional E-value: 3.8 nSTAND_NTPase5 94 ekekwllvvDdadlvade.lakllkklekegrk.vlvllaeRdn 135 +k+ll++D d e l+ + + ++ke+ + ++l++R+ FUN_000603-T1 225 NPSKVLLMLDGLDEADPEkLTLFCTLVQKEELPgCFIVLTSRHE 268 47788888888887655405555555666666699999999985 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.0 1.8e-07 0.00021 17 143 .. 142 273 .. 133 302 .. 0.79 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 1.8e-07 NB-ARC 17 elqivalvGmgGvGKttLakeifnklseveg.rFd.vvawvvvsktfseeelledilkeLgkeeddldekeeselaeklrrlLltk..rfllvlDD 108 +++v + G +G+GKtt ++ + ++ +g ++d ++ + v +e+ +i++ + + + l + e e + ++L++ ++ll+lD FUN_000603-T1 142 RPKVVLIEGEPGMGKTTYCRKLAYDWATRQGrTWDkSFPRIEVLLLLRCREIESSIWEAIDE--QILPQGIEPEVRDVFIQFLRENpsKVLLMLDG 235 4679******************99999888779**9999*********************33..3555666677999999****999999999996 PP NB-ARC 109 v..weeedwekigv.vlpdrenkskvllTtRseevaea 143 + e++ + v +++ ++ ++lT+R e+ +++ FUN_000603-T1 236 LdeADPEKLTLFCTlVQKEELPGCFIVLTSRHEAGSNI 273 51134444655554145556679********9876655 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 3.4e-06 0.0039 5 109 .. 143 252 .. 139 269 .. 0.72 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 3.4e-06 AAA_22 5 agilvltGesGtGKTtllrrlleqldee.....ddsvvlvelpsstspkdllrellralglelekelskeellaalqealkalaaravliiDEaqn 95 +++++ Ge+G+GKTt +r+l+ + d+s+ ++e+ +++ + +a++++ ++ + e+++ + + l++ ++++l++D + FUN_000603-T1 143 PKVVLIEGEPGMGKTTYCRKLAYDWATRqgrtwDKSFPRIEVLLLLRCREIESSIWEAIDEQILPQGIEPEVRDVFIQFLRENPSKVLLMLDGLDE 238 67899***************9865444459999555555555555555666666666666666665566788899999999998889999999888 PP AAA_22 96 lseelleeLrslln 109 +e l + +l++ FUN_000603-T1 239 ADPEKLTLFCTLVQ 252 87777776666655 PP >> AAA_25 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 7.1e-06 0.0082 34 65 .. 144 177 .. 138 192 .. 0.84 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 7.1e-06 AAA_25 34 elillaGapgtGKttlaldlalava..tGkpwlg 65 +++l+ G pg GKtt + la+++a +G+ w FUN_000603-T1 144 KVVLIEGEPGMGKTTYCRKLAYDWAtrQGRTWDK 177 7899**********************99**9954 PP >> VapE-like_dom Virulence-associated protein E-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 6.9e-05 0.08 43 80 .. 133 171 .. 104 196 .. 0.84 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 6.9e-05 VapE-like_dom 43 vfeP..GckfdtvlvLeGaqGigKstflekLagekwfsds 80 +f P ck v+ +eG+ G+gK+t ++kLa +w + + FUN_000603-T1 133 IFAPhkDCKRPKVVLIEGEPGMGKTTYCRKLAY-DWATRQ 171 56555579999*********************9.998874 PP >> Zeta_toxin Zeta toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 8.6e-05 0.1 12 39 .. 138 166 .. 129 173 .. 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 8.6e-05 Zeta_toxin 12 sq.erPvavllaGqpGAGKtelaellkee 39 ++ +rP++vl+ G pG GKt+ ++l+ FUN_000603-T1 138 KDcKRPKVVLIEGEPGMGKTTYCRKLAYD 166 4559*****************99998765 PP >> RNA_helicase RNA helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.00019 0.23 1 33 [. 146 178 .. 146 183 .. 0.85 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00019 RNA_helicase 1 iwlyGpsgeGKStlakelakallkklklpkkds 33 +++ G++g GK+t++++la +++++ + ++++s FUN_000603-T1 146 VLIEGEPGMGKTTYCRKLAYDWATRQGRTWDKS 178 6799*****************998877766555 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00023 0.26 29 126 .. 137 234 .. 121 241 .. 0.77 2 ? -3.4 0.0 6.6 7.7e+03 75 118 .. 485 528 .. 484 530 .. 0.75 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00023 TniB 29 apkkkrmpnlllvGdsnnGKstivekFarlhpaqk.eedeeevpvvvvqappepdekrlyaaiLeaLeapikardrlskleqqvlelLralkvrmL 123 + + kr++ +l+ G++ +GK+t ++k a + ++ ++ ++ p + v + ++ +++ ++i ea+ +i + + ++ +++Lr+ ++L FUN_000603-T1 137 HKDCKRPKVVLIEGEPGMGKTTYCRKLAYDWATRQgRTWDKSFPRIEVLLLLRC--REIESSIWEAIDEQILPQGIEPEVRDVFIQFLRENPSKVL 230 456789999*****************9966655541444555566666666677..7788999999999999999999999999999999998876 PP TniB 124 .iiD 126 ++D FUN_000603-T1 231 lMLD 234 1455 PP == domain 2 score: -3.4 bits; conditional E-value: 6.6 TniB 75 vqappepdekrlyaaiLeaLeapikardrlskleqqvlelLral 118 v +++e++ + + ++i+ ++a ++++ + + l++++++ FUN_000603-T1 485 VAMRSEAKAESIVKSIVSIVNASGHISRVYKMHLSLALRFISEC 528 67899999999999999999888777777766666666666666 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00024 0.28 1 69 [. 146 239 .. 146 270 .. 0.61 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00024 AAA 1 lllyGppGtGKTllakavakelgae..............fveisgselvsk.........yvgesekklrelfeeakkka..psvifiDEiDal 69 +l+ G pG+GKT+ ++ +a ++ ++ ++ + + e+ s+ + e ++r++f + +++ + ++++D +D+ FUN_000603-T1 146 VLIEGEPGMGKTTYCRKLAYDWATRqgrtwdksfprievLLLLRCREIESSiweaideqiLPQGIEPEVRDVFIQFLRENpsKVLLMLDGLDEA 239 6889***************998432233333343333333444444444446666666665555566677777664333322355666666665 PP >> ATPase KaiC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00024 0.28 18 48 .. 142 172 .. 131 174 .. 0.87 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00024 ATPase 18 egrvvlisGepGtGKtifglqFlingaekyg 48 + +vvli GepG GKt+ + + ++ a + g FUN_000603-T1 142 RPKVVLIEGEPGMGKTTYCRKLAYDWATRQG 172 5689****************99998887766 PP >> SRP54 SRP54-type protein, GTPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00031 0.36 1 26 [. 143 168 .. 143 175 .. 0.84 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00031 SRP54 1 psvillvGlqGsGKTttiaKLaallk 26 p+v+l+ G G+GKTt + KLa FUN_000603-T1 143 PKVVLIEGEPGMGKTTYCRKLAYDWA 168 6899******************7554 PP >> SLFN-g3_helicase Schlafen group 3, DNA/RNA helicase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.59 6.8e+02 157 180 .. 66 89 .. 27 121 .. 0.78 2 ? 8.9 0.0 0.00095 1.1 2 29 .. 144 170 .. 143 183 .. 0.84 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.59 SLFN-g3_helicase 157 sqfRvgasddvlawvdalldkdke 180 +q R++ ++++++w++++ + ++ FUN_000603-T1 66 NQARMSHPSSIIKWIQKIYATREG 89 799*************99876654 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00095 SLFN-g3_helicase 2 avvlveGgaGtGKsvvalnllaeleksd 29 +vvl+eG++G GK+ +l++++ ++ FUN_000603-T1 144 KVVLIEGEPGMGKTTYCRKLAYDW-ATR 170 89******************9999.333 PP >> TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00039 0.45 17 45 .. 139 167 .. 124 176 .. 0.83 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00039 TsaE 17 llkagdvvlLeGdLGaGKTtlvkglakal 45 +k+ +vvl+eG+ G GKTt +++la FUN_000603-T1 139 DCKRPKVVLIEGEPGMGKTTYCRKLAYDW 167 4677899*****************98765 PP >> SF3A3 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.2 0.001 1.2 9 31 .. 40 64 .. 37 66 .. 0.93 2 ? -1.6 0.1 3.6 4.1e+03 10 24 .. 434 448 .. 434 462 .. 0.80 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.001 SF3A3 9 GryLDLhelheeYlNlkksg..lsY 31 G++L + + + +YlN + s+ lsY FUN_000603-T1 40 GKFLNMRTAYGRYLNSTMSNllLSY 64 9****************99999988 PP == domain 2 score: -1.6 bits; conditional E-value: 3.6 SF3A3 10 ryLDLhelheeYlNl 24 ry+ Lh+ ++e+ FUN_000603-T1 434 RYVFLHKSFQEFFSA 448 799999999999765 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 3.1 0.0083 9.7 2 61 .] 601 668 .. 600 668 .. 0.65 2 ? 6.6 7.2 0.0079 9.2 2 61 .] 629 696 .. 628 696 .. 0.73 3 ? 5.5 6.6 0.017 20 2 46 .. 657 705 .. 656 724 .. 0.62 4 ? 2.3 0.7 0.17 2e+02 24 37 .. 739 752 .. 712 754 .. 0.63 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0083 LRR_8 2 nLrsLdLssNrltsldd....gaFkglsnLkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgNrL 61 +L+sL L+++++ + + +a + +++L++L Ls+N++ ++l +a++ + L+sL Ls+N + FUN_000603-T1 601 SLTSLRLCRSYIGDEGAnslsQALRANTSLTSLVLSYNSIgykgaDFL-SQALRTNTTLTSLVLSDNSI 668 67777777777765554111134455799*********9933333344.47888888888888888875 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0079 LRR_8 2 nLrsLdLssNrlt....slddgaFkglsnLkvLdLsnNll.....ttlspgafsgLpsLrsLdLsgNrL 61 +L+sL+Ls+N++ + +a + ++ L++L Ls+N++ ++ls +a++ +sL+sL+Ls+N + FUN_000603-T1 629 SLTSLVLSYNSIGykgaDFLSQALRTNTTLTSLVLSDNSIgdegaNSLS-QALRVNTSLTSLNLSSNSI 696 78889999998862222333456667899**********9555555675.7777789*********986 PP == domain 3 score: 5.5 bits; conditional E-value: 0.017 LRR_8 2 nLrsLdLssNrltslddgaFkg....lsnLkvLdLsnNllttlspgafs 46 +L+sL+Ls+N++ + + + + +++L++L+Ls+N++ ++++s FUN_000603-T1 657 TLTSLVLSDNSIGDEGANSLSQalrvNTSLTSLNLSSNSIGDKGANSLS 705 6888888888887655544443211268999999999999766555554 PP == domain 4 score: 2.3 bits; conditional E-value: 0.17 LRR_8 24 lsnLkvLdLsnNll 37 ++ L++L Ls+N++ FUN_000603-T1 739 NTTLTSLVLSDNSI 752 45566666666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (773 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 717 (0.0280681); expected 510.9 (0.02) Passed bias filter: 630 (0.0246624); expected 510.9 (0.02) Passed Vit filter: 96 (0.00375807); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 22 [number of targets reported over threshold] # CPU time: 0.43u 0.37s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7370.25 // Query: FUN_000604-T1 [L=475] Description: FUN_000604 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-83 280.2 0.0 4.4e-83 279.9 0.0 1.1 1 GT4-conflict Family 4 Glycosyltransferase in conflict sys 1.5e-18 67.4 0.0 3.3e-18 66.3 0.0 1.6 1 Glycos_transf_1 Glycosyl transferases group 1 7.4e-18 65.7 0.0 2e-17 64.3 0.0 1.7 2 Glyco_trans_1_4 Glycosyl transferases group 1 0.00037 21.3 0.0 0.0013 19.6 0.0 1.9 2 Glyco_trans_4_4 Glycosyl transferase 4-like domain ------ inclusion threshold ------ 0.056 13.6 0.0 0.11 12.7 0.0 1.5 1 Glyco_transf_5 Starch synthase catalytic domain 0.24 10.9 0.0 0.43 10.0 0.0 1.3 1 DUF6716 Putative glycosyltransferase (DUF6716) Domain annotation for each model (and alignments): >> GT4-conflict Family 4 Glycosyltransferase in conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 279.9 0.0 1e-86 4.4e-83 2 385 .] 19 384 .. 18 384 .. 0.92 Alignments for each domain: == domain 1 score: 279.9 bits; conditional E-value: 1e-86 GT4-conflict 2 vvatewssakGGistfNreLceaLAaaga.eviclVpeaseeeiadAkaagVrLvkaeaepgvsereslllrrpelpagvepdlviGHgrvtGpaA 96 ++a ew+s+kGG+st+NreL++ LA+ ++ ev+ p+ s+e+ ++Ak + + +v+ae++pg +e l+ +p+ +++ d+v+GHg G+ A FUN_000604-T1 19 ILASEWGSSKGGLSTINRELAIQLAKSHDvEVTFFLPKCSPENKEEAKCHYISVVEAERKPGYEELD-WLSFAPQ---DLQIDIVVGHGVKLGKQA 110 5799***********************999***********************************99.5555544...6778************** PP GT4-conflict 97 kalaedfypdakrvhfvHmapdelewlkekrdaaeraeerekierelaakAdlvvaVGprLaeearrllseapgepkvleldpgfdveaeeeprtp 192 +++++ + ++k +++vH++p++l ++k +++ ++e+++ +e+el++ Adlvv+VGp+L+e +r+ l+ +++++vle++p + +++ + +++ FUN_000604-T1 111 QVIRKSH--KCKWIQVVHTDPEKLGMFKCYENPISKGEQKHHVEVELCQMADLVVGVGPKLTEAFRKYLRWSKKDQDVLEFTPSVFTDFVRVEQAL 204 *******..************************************************************99999************9999888888 PP GT4-conflict 193 peggklkvLllGRae..DaelKgldlAaravgrlakesrderveLvvrGapaeeaeelrerlaeiagepalevtvrpytkdraeleadlrraslvl 286 +e+++ +vL++GR + D +lKg d+Aar v++l + +Lv +Gap+++ +e ++rl + +g p+ ++tvr ++ dr++l++ + + +lvl FUN_000604-T1 205 EERKPRSVLVFGRGDdeDFKLKGFDIAARSVAALPD------TDLVFVGAPDGKEQEIAKRLLD-SGIPQGRLTVRGFK-DRESLKHLFCEVDLVL 292 899***********988999***********88866......67*******************9.79999********5.899************* PP GT4-conflict 287 mPSraEGFGLvglEAiaagvPvLvsseSGlaelLeek.lseeeaerlvvpvtgddeedaeewaraieevlrdleaaferaaelreeLaer.ltWaa 380 mPSr+EGFGL+glEA++ag+Pv+vs++SG++e L + + ++++v++ ++d+ +w++ai+ ++++ ++++ + +++ e+ e+ + W++ FUN_000604-T1 293 MPSRTEGFGLTGLEALSAGLPVIVSKNSGFGEALGNVpF----GSSFVID-SEDP----SAWTAAIKGIWNKDRQTRLDETKVLCEFYEKrYGWSE 379 **********************************99933....5567777.4444....7**********877777666666666665555****9 PP GT4-conflict 381 aaasL 385 +++L FUN_000604-T1 380 QCENL 384 99876 PP >> Glycos_transf_1 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.3 0.0 7.7e-22 3.3e-18 27 158 .. 225 355 .. 200 365 .. 0.88 Alignments for each domain: == domain 1 score: 66.3 bits; conditional E-value: 7.7e-22 Glycos_transf_1 27 eKgldlllkafaklkeklkpdlklviaG..dgeeekklkklaeklglednvkflgfvsdedlpellkiadvfvlpsrsEgfGivllEAmaaglp 118 Kg+d + +++a pd+ lv++G dg+e++ k+l ++ + ++++ gf+++e l++l+ d++++psr+EgfG++ lEA++aglp FUN_000604-T1 225 LKGFDIAARSVAA-----LPDTDLVFVGapDGKEQEIAKRLLDSGIPQGRLTVRGFKDRESLKHLFCEVDLVLMPSRTEGFGLTGLEALSAGLP 313 4777777777775.....599************************************************************************* PP Glycos_transf_1 119 viasdvgglrevvkdge..tGllvkpnnaealaeaieklled 158 vi+s+++g+ e +++ + ++++++++ a+ +ai+ + ++ FUN_000604-T1 314 VIVSKNSGFGEALGNVPfgSSFVIDSEDPSAWTAAIKGIWNK 355 *************99777799**************9977665 PP >> Glyco_trans_1_4 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.3 9.8e+03 37 68 .. 161 196 .. 157 204 .. 0.61 2 ! 64.3 0.0 4.7e-21 2e-17 3 139 .. 211 353 .. 209 355 .. 0.81 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.3 Glyco_trans_1_4 37 vivGdgpeeeeeleelak...gledrveftGfv.ed 68 ++vG gp+ e++++ ++ + +d eft v +d FUN_000604-T1 161 LVVGVGPKLTEAFRKYLRwskKDQDVLEFTPSVfTD 196 578888866656666554443333447777777554 PP == domain 2 score: 64.3 bits; conditional E-value: 4.7e-21 Glyco_trans_1_4 3 vilfvGrl.ae..nekgvdllleavplvrkkerdvrlvivG..dgpeeeeeleelak..gledr.veftGfv..edlaellaaadvfvlPslse 86 +l +Gr +e + kg+d+ ++ v+++ + + lv+vG dg +e+e+ +++ g+ ++ ++ Gf e l+ l+ + d++++Ps++e FUN_000604-T1 211 SVLVFGRGdDEdfKLKGFDIAARSVAALPD----TDLVFVGapDG--KEQEIAKRLLdsGIPQGrLTVRGFKdrESLKHLFCEVDLVLMPSRTE 298 577778885557788999999999999993....57999993344..445776655338988667*******8666****************** PP Glyco_trans_1_4 87 gfglkllEAmaaglPvVatdvggipevvedg..engllvppgdpealaeailrll 139 gfgl+ lEA++aglPv++++ +g+ e++ + + ++++++dp a+ +ai ++ FUN_000604-T1 299 GFGLTGLEALSAGLPVIVSKNSGFGEALGNVpfGSSFVIDSEDPSAWTAAIKGIW 353 **************************9944443345**************98765 PP >> Glyco_trans_4_4 Glycosyl transferase 4-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 3e-07 0.0013 1 144 [. 29 175 .. 29 188 .. 0.73 2 ? -1.7 0.0 1.1 4.7e+03 22 24 .. 289 291 .. 254 321 .. 0.52 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 3e-07 Glyco_trans_4_4 1 gGvaryvrelaealaar.GheVrvltpaadpgrprleeagvrvrrlp.vpprpsglarlaalrrlrrllraerpdvvhahsplsg.laarlarr 91 gG ++ rela +la++ +eV+++ p +p+ eea ++++++ + ++p +++ l +l + ++ ++d+v++h+ ++g +a ++ + FUN_000604-T1 29 GGLSTINRELAIQLAKShDVEVTFFLPKCSPENK--EEAKCHYISVVeAERKP----GYEELDWLSFAPQDLQIDIVVGHGVKLGkQAQVIRK- 115 8999999********8714455556666666665..56678877643255555....6888899999989***********998846666666. PP Glyco_trans_4_4 92 ragvPlvvtvhglalaeg......sglkkrla.ralerrllrradaviavseaeaellra 144 ++ ++++ vh++ + g ++ +k + +e l + ad v+ v + + e++r FUN_000604-T1 116 SHKCKWIQVVHTDPEKLGmfkcyeNPISKGEQkHHVEVELCQMADLVVGVGPKLTEAFRK 175 ***********755333333333455554444599**************99999999987 PP == domain 2 score: -1.7 bits; conditional E-value: 1.1 Glyco_trans_4_4 22 rvl 24 +++ FUN_000604-T1 289 DLV 291 222 PP >> Glyco_transf_5 Starch synthase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 2.6e-05 0.11 1 60 [. 16 74 .. 16 120 .. 0.76 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.6e-05 Glyco_transf_5 1 kilfvasEvapfaktGGLadvvgaLpkaLak.lghdvrvilpkygkikeereqleevaels 60 k+ ++asE GGL+ + ++L+ +Lak + ++v+ +lpk++ ++e + +++ ++ FUN_000604-T1 16 KVTILASEWGS--SKGGLSTINRELAIQLAKsHDVEVTFFLPKCSPENKEEAKCHYISVVE 74 68889999976..89**************7625679999*****66666665666665543 PP >> DUF6716 Putative glycosyltransferase (DUF6716) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.0001 0.43 271 305 .. 305 339 .. 302 352 .. 0.90 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0001 DUF6716 271 lEAvaagvpvlvLddfGvseellntvFegSgllgs 305 lEA++ag+pv+v ++ G +e+l+n F S ++ s FUN_000604-T1 305 LEALSAGLPVIVSKNSGFGEALGNVPFGSSFVIDS 339 9**************************88866654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (475 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 696 (0.027246); expected 510.9 (0.02) Passed bias filter: 624 (0.0244275); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4561.56 // Query: FUN_000605-T1 [L=120] Description: FUN_000605 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-08 35.5 5.0 1.2e-08 35.5 5.0 2.5 2 EGF_CA Calcium-binding EGF domain ------ inclusion threshold ------ 0.032 14.9 5.6 0.032 14.9 5.6 2.7 2 EGF_3 EGF domain 0.058 13.7 3.5 0.058 13.7 3.5 2.4 2 cEGF Complement Clr-like EGF-like Domain annotation for each model (and alignments): >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 9.5 0.82 6.9e+03 19 38 .. 69 86 .. 52 91 .. 0.72 2 ! 35.5 5.0 1.4e-12 1.2e-08 1 29 [. 93 120 .] 93 120 .] 0.98 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.82 EGF_CA 19 CvNteGsfeCvCeegyenne 38 C+ + eC+C+ g++ FUN_000605-T1 69 CNENHCCGECRCQTGFT--G 86 555555669*******9..2 PP == domain 2 score: 35.5 bits; conditional E-value: 1.4e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCv 29 DvdEC g++ C ++n+ CvNt+Gs++C+ FUN_000605-T1 93 DVDECILGNNAC-QANSNCVNTIGSYRCQ 120 9***********.9**************6 PP >> EGF_3 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 9.7 0.15 1.3e+03 21 31 .. 76 86 .. 68 91 .. 0.79 2 ? 14.9 5.6 3.8e-06 0.032 1 24 [. 97 120 .] 97 120 .] 0.94 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.15 EGF_3 21 fkCtCkagytG 31 +C+C++g+tG FUN_000605-T1 76 GECRCQTGFTG 86 58********9 PP == domain 2 score: 14.9 bits; conditional E-value: 3.8e-06 EGF_3 1 CsknnggChanAtCtntegsfkCt 24 C +n+ C an +C nt gs++C+ FUN_000605-T1 97 CILGNNACQANSNCVNTIGSYRCQ 120 7789*******************7 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 3.5 6.8e-06 0.058 4 24 .] 78 96 .. 77 96 .. 0.82 2 ? 0.5 0.5 0.092 7.8e+02 1 5 [. 116 120 .] 116 120 .] 0.91 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 6.8e-06 cEGF 4 CsCppGYtLagDGrt..CvDIDE 24 C C G+t+ ++ C+D+DE FUN_000605-T1 78 CRCQTGFTG----KHpdCTDVDE 96 ********4....4444*****9 PP == domain 2 score: 0.5 bits; conditional E-value: 0.092 cEGF 1 SYtCs 5 SY+C+ FUN_000605-T1 116 SYRCQ 120 9***7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1251 (0.0489724); expected 510.9 (0.02) Passed bias filter: 546 (0.021374); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1197.23 // Query: FUN_000606-T1 [L=407] Description: FUN_000606 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-26 92.1 14.0 3.4e-26 92.1 14.0 2.8 3 PAP2_C PAP2 superfamily C-terminal 6.9e-10 39.6 0.1 1.1e-09 39.0 0.1 1.3 1 SAM_1 SAM domain (Sterile alpha motif) 0.00015 22.3 0.1 0.00026 21.5 0.1 1.4 1 SAM_2 SAM domain (Sterile alpha motif) 0.0035 17.7 0.0 0.0074 16.7 0.0 1.4 1 SAM_3 SAM domain (Sterile alpha motif) ------ inclusion threshold ------ 0.018 15.5 0.0 0.033 14.6 0.0 1.4 1 SAM_PNT Sterile alpha motif (SAM)/Pointed domain 0.31 11.6 0.4 0.59 10.7 0.4 1.4 1 DUF3545 Protein of unknown function (DUF3545) Domain annotation for each model (and alignments): >> PAP2_C PAP2 superfamily C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.2 1.1 4.8e+03 33 45 .. 143 156 .. 127 164 .. 0.46 2 ? -0.5 0.9 0.63 2.7e+03 41 52 .. 201 211 .. 181 239 .. 0.55 3 ! 92.1 14.0 7.9e-30 3.4e-26 1 74 [] 280 353 .. 280 353 .. 0.99 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.1 PAP2_C 33 kvilwl.lalvgyf 45 +v++++ +++v++f FUN_000606-T1 143 SVVYAFsVFFVTSF 156 33333202223333 PP == domain 2 score: -0.5 bits; conditional E-value: 0.63 PAP2_C 41 lvgyfliiasrk 52 +v ++++i +k FUN_000606-T1 201 VV-LAIVIFLHK 211 21.122222222 PP == domain 3 score: 92.1 bits; conditional E-value: 7.9e-30 PAP2_C 1 tCgDlifSGHtvvltllvlfileyspkklkilkvilwllalvgyfliiasrkHYtvDVllglyistlvfllyhl 74 tCgD++fSGHtv++tll +fi ey+p ++ l++++w+l+++g+f+i+a+++HY++DV++++yi++++fl+yh+ FUN_000606-T1 280 TCGDYMFSGHTVSITLLNFFISEYTPAHMYYLHTCCWVLNMFGIFFILAAHEHYSIDVVIAFYITSRLFLYYHT 353 7***********************************************************************96 PP >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.0 0.1 2.6e-13 1.1e-09 2 62 .. 11 74 .. 10 76 .. 0.94 Alignments for each domain: == domain 1 score: 39.0 bits; conditional E-value: 2.6e-13 SAM_1 2 gwsvedVgeWLesiglgqYadsF.rkgyidgetLlqlteddLek..lgvtllgHrkkIlsaiqr 62 w++ dV+ WL+ g++ Y + F + ++idg++Ll ++e+dL++ l + lg+ k++ ++i++ FUN_000606-T1 11 DWTCGDVRLWLQGKGFSNYSNIFsKDHKIDGKALLAMDESDLRNppLELKILGDIKRLWLEIDA 74 7*****************************************998999999******9999875 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.1 6.1e-08 0.00026 4 65 .. 12 75 .. 9 76 .. 0.87 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 6.1e-08 SAM_2 4 wslesvaeWLrsigleqykdnFk.dagitgaelllrlteedL....kelGitsvghrkkilkkiqel 65 w+ +v WL+ g++ y ++F+ d++i+g ++ll ++e+dL el+i +g+ k+++ +i+++ FUN_000606-T1 12 WTCGDVRLWLQGKGFSNYSNIFSkDHKIDG-KALLAMDESDLrnppLELKI--LGDIKRLWLEIDAI 75 9999******************637*****.***********887557777..88888888888765 PP >> SAM_3 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 1.7e-06 0.0074 14 49 .. 16 53 .. 13 55 .. 0.82 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 1.7e-06 SAM_3 14 eVkaWLtakgFskk..tvksLgklsGaqllslskeeLk 49 +V+ WL+ kgFs++ + ++ +k +G+ ll++++++L+ FUN_000606-T1 16 DVRLWLQGKGFSNYsnIFSKDHKIDGKALLAMDESDLR 53 9***********84115555578************996 PP >> SAM_PNT Sterile alpha motif (SAM)/Pointed domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 7.8e-06 0.033 17 63 .. 9 54 .. 3 79 .. 0.75 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 7.8e-06 SAM_PNT 17 PqeWtkehVleWlewavkefd.lskidfsefemsGkeLcsltkeefle 63 q+Wt +V+ Wl+ k f+ s+i ++ +++Gk+L+++ + ++++ FUN_000606-T1 9 VQDWTCGDVRLWLQG--KGFSnYSNIFSKDHKIDGKALLAMDESDLRN 54 689**********85..45441678888999************99986 PP >> DUF3545 Protein of unknown function (DUF3545) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.4 0.00014 0.59 24 39 .. 65 80 .. 58 83 .. 0.90 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00014 DUF3545 24 kKRkWREIEaikdryr 39 KR W EI ai+ r r FUN_000606-T1 65 IKRLWLEIDAIQQRNR 80 5*************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (407 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1051 (0.0411431); expected 510.9 (0.02) Passed bias filter: 509 (0.0199256); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3980.27 // Query: FUN_000607-T1 [L=372] Description: FUN_000607 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-15 57.2 0.0 2e-15 57.2 0.0 4.6 4 CDC37_C Cdc37 C terminal domain 5e-14 52.7 1.3 5e-14 52.7 1.3 2.6 3 CDC37_M Cdc37 Hsp90 binding domain 1.1e-13 52.7 21.2 1.1e-13 52.7 21.2 3.1 2 CDC37_N Cdc37 N terminal kinase binding 0.00036 20.3 0.4 0.0094 15.8 0.0 2.6 2 UBM Ubiquitin binding region ------ inclusion threshold ------ 0.041 14.3 8.0 0.71 10.3 1.2 2.7 2 PBDC1 PBDC1 protein 0.042 14.6 0.5 0.15 12.9 0.5 1.9 1 DUF6494 Family of unknown function (DUF6494) 0.18 13.0 5.0 0.42 11.8 2.0 2.4 2 CATRA-C CASPASE and TPR Repeat-Associated C-terminal domai 0.99 9.4 6.0 0.91 9.5 1.3 2.7 2 Imm49 Immunity protein 49 4.7 7.0 32.6 0.22 11.4 23.2 2.3 2 GAS Growth-arrest specific micro-tubule binding 7.4 5.0 9.7 3.2 6.2 3.4 2.1 2 Prominin Prominin Domain annotation for each model (and alignments): >> CDC37_C Cdc37 C terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.7 9.6 10 2.6e+04 74 97 .. 78 101 .. 37 106 .. 0.70 2 ? -6.3 12.1 10 2.6e+04 34 96 .. 94 152 .. 79 156 .. 0.67 3 ? 3.9 2.8 0.033 83 16 90 .. 210 285 .. 196 291 .. 0.71 4 ! 57.2 0.0 7.9e-19 2e-15 8 88 .. 293 368 .. 288 372 .] 0.86 Alignments for each domain: == domain 1 score: -5.7 bits; conditional E-value: 10 CDC37_C 74 teegekelkeleeeakeekkeeee 97 ++e +++l++l++++ke kkeeee FUN_000607-T1 78 EKELKDKLQKLQKKQKELKKEEEE 101 255566677777777766665554 PP == domain 2 score: -6.3 bits; conditional E-value: 10 CDC37_C 34 sLdevnkvlakmkveeAeeilellgeagilsleeelvdatteegekelkeleeeakeekkeee 96 +L + ++ lak k ++A + ++ l++ag ++++a +++ e++l e e+++k+++ +e+ FUN_000607-T1 94 ELKKEEEELAK-KEKKAPKNVDTLSQAGFT---RTIINAPKKNQEDNLTEDEKAEKSQAFMEK 152 44444455554.456788888999999887...888899999999999888888887766665 PP == domain 3 score: 3.9 bits; conditional E-value: 0.033 CDC37_C 16 veiFeklpkelqkAlktksLdevnkvlakmkveeAe..eilellgeagilsleeelvdatteegekelkeleeeake 90 i + el k l+t ++n + kmk + e e++e +++ ++ s+ e + + ++ ek +ke e+e++e FUN_000607-T1 210 QTIIMQYMLELAKSLDTTPRATINSFFVKMKRAKTEfkEYMEAFDD-ELRSFLERVKERAQARIEKAMKEAEQEERE 285 556666677899999999999*********986554339*****98.788888888444445555555555555443 PP == domain 4 score: 57.2 bits; conditional E-value: 7.9e-19 CDC37_C 8 edpeevkaveiFeklpkelqkAlktksLdevnkvlakmkveeAeeilellgeagilsleeelvdatteegekelkeleeea 88 dp ve+Fe+lp+elqk++++k++ ++++vl+ m+ eeA +l+++ ++g++ +++ +a ee e e ++ e+ FUN_000607-T1 293 LDP-----VEVFESLPPELQKCFEEKDIPMLQEVLGRMPEEEARTYLKKCVDSGLWIPNAQDAQAHAEEAEPESEHYEAVG 368 555.....9***********************************************7777777777788888888877654 PP >> CDC37_M Cdc37 Hsp90 binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.2 0.55 1.4e+03 91 112 .. 79 100 .. 73 101 .. 0.88 2 ? -2.2 0.0 2.1 5.5e+03 81 99 .. 141 159 .. 136 161 .. 0.72 3 ! 52.7 1.3 2e-17 5e-14 5 106 .. 163 270 .. 159 278 .. 0.87 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.55 CDC37_M 91 edveetynhiktRaeiikkeqe 112 ++++++ ++++++ +++kke+e FUN_000607-T1 79 KELKDKLQKLQKKQKELKKEEE 100 57889999**********9987 PP == domain 2 score: -2.2 bits; conditional E-value: 2.1 CDC37_M 81 kshqakklFledveetynh 99 ++++++++F+e+ ++ ++h FUN_000607-T1 141 EKAEKSQAFMEKYKKEIEH 159 4555688899998888877 PP == domain 3 score: 52.7 bits; conditional E-value: 2e-17 CDC37_M 5 iklgdykkseefllkhpeilseqekDaLlveaFdaqlegkekkakqvvhqslLlqyirqL.....egakngvklFfkkittkshqa...kklFled 92 + +dy++s+e++ ++p++ +e + ++L + + ++++k++ +++v hq +++qy+ +L + + +++ Ff k+++ +++ ++F ++ FUN_000607-T1 163 L--SDYNDSQEYMRENPHLACEDTANYLALWCINLEVQEKHSLMERVAHQTIIMQYMLELaksldTTPRATINSFFVKMKRAKTEFkeyMEAFDDE 256 4..5********************************************************99999777799*****9995554433124899**** PP CDC37_M 93 veetynhiktRaei 106 +++ +++k+Ra++ FUN_000607-T1 257 LRSFLERVKERAQA 270 ***********986 PP >> CDC37_N Cdc37 N terminal kinase binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.7 21.2 4.3e-17 1.1e-13 1 109 [. 1 109 [. 1 175 [. 0.77 2 ? 1.1 1.3 0.38 9.8e+02 34 77 .. 241 284 .. 193 340 .. 0.60 Alignments for each domain: == domain 1 score: 52.7 bits; conditional E-value: 4.3e-17 CDC37_N 1 pldYskWDklELSDDsDievHPNVDkrsfirwKqrdihekreqrkaeikklkaereinekllkrikkllealkkkevee..eevvfkalnesladk 94 ++dYskWD++E+SDD+D ++HPN+D s+ rw+++ e+ e+ ++e +++ + +e n+k l+++++ l+ l+ ++++e + +++l+++ ++ FUN_000607-T1 1 MVDYSKWDHIEVSDDED-DTHPNIDTPSLFRWRHQARVERMEEARKERETIDSRIEENNKNLRQVREKLKDLSPTGDSEkeLKDKLQKLQKKQKEL 95 69***************.***************9999999999999********************999999999888833223344444444322 PP CDC37_N 95 kekedapkaekeeeq 109 k++e++ ++ e+++ FUN_000607-T1 96 KKEEEELAKK-EKKA 109 2222222222.1111 PP == domain 2 score: 1.1 bits; conditional E-value: 0.38 CDC37_N 34 qrdihekreqrkaeikklkaereinekllkrikkllealkkkev 77 ++++ k ++ + + + +++e+ + ri+k +++ +++e FUN_000607-T1 241 RAKTEFKEYMEAFDDELRSFLERVKERAQARIEKAMKEAEQEER 284 33333333333333333333334444444444444444444443 PP >> UBM Ubiquitin binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.1 2.6e+02 12 22 .. 248 258 .. 246 261 .. 0.88 2 ! 15.8 0.0 3.7e-06 0.0094 6 22 .. 290 307 .. 288 308 .. 0.91 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.1 UBM 12 sFLaaLPpdLR 22 ++++a++++LR FUN_000607-T1 248 EYMEAFDDELR 258 789******** PP == domain 2 score: 15.8 bits; conditional E-value: 3.7e-06 UBM 6 peeiDp.sFLaaLPpdLR 22 p + Dp +++++LPp+L+ FUN_000607-T1 290 PGGLDPvEVFESLPPELQ 307 6788*************9 PP >> PBDC1 PBDC1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 1.2 0.00028 0.71 54 102 .. 133 179 .. 85 190 .. 0.89 2 ? 7.7 0.4 0.0018 4.6 40 81 .. 219 260 .. 180 278 .. 0.81 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00028 PBDC1 54 dedelkskeakekWreflekfeekveDynlGtllRldakkeyseentil 102 +ed+l ++e+ ek ++f+ek+++++e + G l + ++ey +en l FUN_000607-T1 133 QEDNLTEDEKAEKSQAFMEKYKKEIEHF--GMLSDYNDSQEYMRENPHL 179 6899999999****************86..8899999999999999766 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0018 PBDC1 40 efrkefpdlkvevldedelkskeakekWreflekfeekveDy 81 e+ k+ + +++++ +k k+ak++++e++e+f++++ + FUN_000607-T1 219 ELAKSLDTTPRATINSFFVKMKRAKTEFKEYMEAFDDELRSF 260 445555566788999999*******************99877 PP >> DUF6494 Family of unknown function (DUF6494) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.5 5.8e-05 0.15 4 37 .. 251 284 .. 249 289 .. 0.90 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 5.8e-05 DUF6494 4 dtfnmsiRKFLKqVGVtSQreIEeavrkalaegk 37 ++f+ ++R FL V +Q IE+a+++a++e++ FUN_000607-T1 251 EAFDDELRSFLERVKERAQARIEKAMKEAEQEER 284 78999***********************998875 PP >> CATRA-C CASPASE and TPR Repeat-Associated C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 2.0 0.00016 0.42 14 78 .. 32 98 .. 29 152 .. 0.72 2 ? 1.4 0.1 0.27 7e+02 26 48 .. 264 286 .. 240 311 .. 0.57 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00016 CATRA-C 14 RyqlRvwqragerlrrlrealdeavaellerldaadegagele....rlldaaallarlraeeagLala 78 R+q+Rv + + ++r+ re++d++++e ++l++ +e+ ++l+ ++ + l++l++++++L FUN_000607-T1 32 RHQARVERME--EARKERETIDSRIEENNKNLRQVREKLKDLSptgdSEKELKDKLQKLQKKQKELKKE 98 9*****8844..8*******************9777777777744442333333344444444444433 PP == domain 2 score: 1.4 bits; conditional E-value: 0.27 CATRA-C 26 rlrrlrealdeavaellerldaa 48 +r+++++++a++e++++ +++ FUN_000607-T1 264 VKERAQARIEKAMKEAEQEEREK 286 22333444444444444433333 PP >> Imm49 Immunity protein 49 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.2 0.11 2.9e+02 152 184 .. 118 150 .. 46 153 .. 0.86 2 ? 9.5 1.3 0.00036 0.91 76 124 .. 238 285 .. 164 302 .. 0.74 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.11 Imm49 152 eegFneaLeealeahreywtadadrrldpdgfl 184 ++gF++++ +a +++ e+ +++++++++++f+ FUN_000607-T1 118 QAGFTRTIINAPKKNQEDNLTEDEKAEKSQAFM 150 789999999999999999998877887777775 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00036 Imm49 76 llresgtqydeyaysyvraLqafllgaqdpdaaeellaameaadpdeaa 124 ++ +++t++ ey+ ++ + L++fl++++ ++a +++ +am+ a+++e++ FUN_000607-T1 238 KMKRAKTEFKEYMEAFDDELRSFLERVK-ERAQARIEKAMKEAEQEERE 285 5677789*******************77.************98888775 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 23.2 8.6e-05 0.22 43 166 .. 34 158 .. 29 172 .. 0.93 2 ? 0.8 1.8 0.14 3.7e+02 40 56 .. 267 283 .. 199 288 .. 0.60 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 8.6e-05 GAS 43 eenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknlkarlkelekelkelkwehevleqrfekverErdelye.kfeeaiqdvq 137 ++ +++e+++e + + +e+ ++++ + +++l++ + s k+lk +l++l+k+ kelk+e+e l ++ +k + d+l++ f+++i + FUN_000607-T1 34 QARVERMEEARKERETIDSRIEENNKNLRQVREKLKDLSPTGDSEKELKDKLQKLQKKQKELKKEEEELAKKEKKAPKNVDTLSQaGFTRTIINAP 129 555678*****************************************************************************8637********* PP GAS 138 qktglknllLekklealseelEkkeaqLe 166 +k + nl k e+ ++ +Ek ++++e FUN_000607-T1 130 KKNQEDNLTEDEKAEKSQAFMEKYKKEIE 158 *******************9999888876 PP == domain 2 score: 0.8 bits; conditional E-value: 0.14 GAS 40 kkeeenekelseieqen 56 + +++ ek ++e+eqe FUN_000607-T1 267 RAQARIEKAMKEAEQEE 283 11223333333333333 PP >> Prominin Prominin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 3.4 0.0013 3.2 232 286 .. 62 116 .. 34 172 .. 0.72 2 ? 2.7 0.4 0.014 36 345 417 .. 215 287 .. 196 291 .. 0.80 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0013 Prominin 232 skvipaLaelerllenlkeakelLeqvnklekeLrksgsqLrdglrgvkrdleqa 286 +v ++L++l +++ ke k++L++++k +keL+k+ ++L + +++ ++++++ FUN_000607-T1 62 RQVREKLKDLSPTGDSEKELKDKLQKLQKKQKELKKEEEELAKKEKKAPKNVDTL 116 3456777777777888888888888888888888888888877666665555544 PP == domain 2 score: 2.7 bits; conditional E-value: 0.014 Prominin 345 arlnkipekvknqtaevvpdlkkalaqireqiktlakeiprealsavlsdle.nterssksfldevekyekyrw 417 +++ ++ + + ++ + ++++ + +++++++++k+ +++ ++ l ++l+ ++ + + ++++ +e e+ e+ ++ FUN_000607-T1 215 QYMLELAKSLDTTPRATINSFFVKMKRAKTEFKEYMEAF-DDELRSFLERVKeRAQARIEKAMKEAEQEEREKR 287 566667777777778888888889999999999999999.8999999999988888888888888888777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (372 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4251 (0.166412); expected 510.9 (0.02) Passed bias filter: 1007 (0.0394206); expected 510.9 (0.02) Passed Vit filter: 181 (0.00708554); expected 25.5 (0.001) Passed Fwd filter: 60 (0.0023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.51u 0.40s 00:00:00.91 Elapsed: 00:00:00.44 # Mc/sec: 3441.73 // Query: FUN_000608-T1 [L=1489] Description: FUN_000608 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-63 212.4 3.9 4.7e-63 211.4 3.9 1.5 1 Rossman_Mical Mical, Rossman domain 9.4e-36 123.3 20.5 1.7e-35 122.5 19.3 2.2 2 bMERB_dom Bivalent Mical/EHBP Rab binding domain 9.9e-24 84.1 0.9 3.4e-23 82.4 0.0 2.4 2 CH Calponin homology (CH) domain 1.5e-05 24.9 0.0 0.00041 20.2 0.0 2.4 2 FAD_binding_3 FAD binding domain 4.4e-05 24.1 6.1 0.0001 23.0 6.1 1.6 1 LIM LIM domain 0.00011 22.2 0.0 0.00043 20.3 0.0 2.0 2 Pyr_redox_2 Pyridine nucleotide-disulphide oxidoreductase 0.00042 20.2 0.0 0.0011 18.8 0.0 1.7 1 Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase 0.003 17.3 0.0 0.0048 16.6 0.0 1.3 1 FAD_binding_2 FAD binding domain 0.0049 17.2 0.0 0.012 15.9 0.0 1.7 1 CAMSAP_CH CAMSAP CH domain 0.0067 16.4 0.0 0.013 15.4 0.0 1.5 1 HI0933_like HI0933-like protein Rossmann domain 0.007 17.1 0.0 0.018 15.8 0.0 1.7 1 NAD_binding_8 NAD(P)-binding Rossmann-like domain ------ inclusion threshold ------ 0.013 15.6 0.4 0.028 14.4 0.0 1.7 2 DAO FAD dependent oxidoreductase 0.027 15.4 0.1 0.11 13.5 0.1 2.1 1 Pyr_redox Pyridine nucleotide-disulphide oxidoreductase 0.043 13.4 0.0 0.069 12.7 0.0 1.3 1 Lycopene_cycl Lycopene cyclase protein 0.096 12.6 0.0 0.23 11.3 0.0 1.6 1 AlaDh_PNT_C Alanine dehydrogenase/PNT, C-terminal domain Domain annotation for each model (and alignments): >> Rossman_Mical Mical, Rossman domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 211.4 3.9 2.8e-66 4.7e-63 1 130 [] 242 371 .. 242 371 .. 1.00 Alignments for each domain: == domain 1 score: 211.4 bits; conditional E-value: 2.8e-66 Rossman_Mical 1 laiaitanfinkkteaeakveeisGvakifnqkffkdlkeetgidlenivyykdethyfvmtakkksllkkgvlkkdledtekllskenvdkeall 96 lai+it+nf+n++t++ea+veeisGva+ifnq+ff+dlk++tgidlenivyykdethyfvm+akkksll+kgv+kkd++d+ +ll+++nv++++ll FUN_000608-T1 242 LAIGITVNFMNRNTKEEARVEEISGVAFIFNQQFFQDLKDSTGIDLENIVYYKDETHYFVMCAKKKSLLQKGVIKKDFQDAYDLLQTSNVNHDKLL 337 8*********************************************************************************************** PP Rossman_Mical 97 kyakeaaefstkkklpklefalnaagkpdvalfd 130 +ya+eaa+f+t+++lp+l+faln+++k+dva+fd FUN_000608-T1 338 AYAREAANFATSSQLPHLDFALNHYRKEDVAMFD 371 *********************************9 PP >> bMERB_dom Bivalent Mical/EHBP Rab binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 8 1.4e+04 100 116 .. 110 126 .. 109 129 .. 0.87 2 ! 122.5 19.3 9.9e-39 1.7e-35 1 134 [. 1345 1475 .. 1345 1476 .. 0.95 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 8 bMERB_dom 100 eeelleelveiVekRde 116 e ll +v ++ekRd+ FUN_000608-T1 110 ESALLGAYVVVIEKRDR 126 6789999********97 PP == domain 2 score: 122.5 bits; conditional E-value: 9.9e-39 bMERB_dom 1 iqreleeieeeqkeleergvelEkkLReesesgeeeeeelleewfeLvneknaLvrreseLmilakeqeLeeeqaeleqelrellekedkekte 94 iqrelee+ ++q++le++g ++Ek+LR + ++g ee++l+ +wf+Lvn+knaL+r eseL+i+a+ +Le++q +leqe+rell ked+ k + FUN_000608-T1 1345 IQRELEEVAVKQADLEKEGIVVEKALR-SGSTGGAEEHHLMLQWFKLVNRKNALIRFESELVIHANSIQLEDQQGRLEQEIRELLMKEDHSKHD 1437 8**************************.67899*******************************************************998875 PP bMERB_dom 95 edkkreeelleelveiVekRdelvesleedrlreeeedee 134 +++ ++ ++lv+iVe+R++lve l+e+r+re+eed++ FUN_000608-T1 1438 --NRAIQQKTKQLVDIVEQRNALVELLDEERKREQEEDRQ 1475 ..56667779****************************87 PP >> CH Calponin homology (CH) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 3.2 5.5e+03 8 34 .. 248 282 .. 246 284 .. 0.83 2 ! 82.4 0.0 2e-26 3.4e-23 4 108 .. 520 623 .. 517 624 .. 0.94 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 3.2 CH 8 lrWinsvlaeygekvkv........enftedlrDG 34 ++++n+ ++e+ + +++ ++f++dl+D+ FUN_000608-T1 248 VNFMNRNTKEEARVEEIsgvafifnQQFFQDLKDS 282 688999998887777779999999999******97 PP == domain 2 score: 82.4 bits; conditional E-value: 2e-26 CH 4 ekellrWinsvlaeygekvkvenftedlrDGlaLckLlnklapglvdkkklnksefdkleNinlaldvaekklgvpkvlieaedlve...gknksv 96 k+ll+W+++++++y ++vk++++++++++Gl +c+++++++p+l+d+++l s++++l N++la+dvae++lg+p+ + a++++ ++ +++ FUN_000608-T1 520 AKDLLKWCQEQTKKY-KNVKINDMSTSWKNGLGFCAIIHHYRPDLIDFSSL--SPKEHLANLQLAFDVAEEHLGIPPQM-SASEMAAkvvPDTLMI 611 699***********9.999********************************..8************************9.99999998989999** PP CH 97 ltllasLfrafq 108 + +++++ ++f+ FUN_000608-T1 612 VSYVSQYHEVFK 623 ******998876 PP >> FAD_binding_3 FAD binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 2.4e-07 0.00041 2 38 .. 93 129 .. 92 132 .. 0.93 2 ? 1.7 0.0 0.097 1.6e+02 152 177 .. 219 244 .. 209 279 .. 0.69 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 2.4e-07 FAD_binding_3 2 tdVlIvGaGpaGlmlallLaraGvrvvlverhaetsv 38 +VlI+GaGp+Gl a + a G vv++e++++ s+ FUN_000608-T1 93 SKVLIIGAGPCGLRIAIESALLGAYVVVIEKRDRFSR 129 68******************************99876 PP == domain 2 score: 1.7 bits; conditional E-value: 0.097 FAD_binding_3 152 YlvGaDGarStvrkslgiefegeekv 177 +vGaDG+rS+ g ef+g+ ++ FUN_000608-T1 219 IIVGADGRRSALKGFKGKEFRGKLAI 244 59********9999989889988876 PP >> LIM LIM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 6.1 5.9e-08 0.0001 1 42 [. 742 783 .. 742 804 .. 0.75 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 5.9e-08 LIM 1 CagCkkkiadrelvrraldkvwHpeCfrCaeCqkeLeegd.fy 42 C C+++i+ e + +a+++ +H+eCf C +C+++L+ g+ y FUN_000608-T1 742 CFFCGRRIYLMERL-SAEGHFFHRECFLCENCGCTLRLGTySY 783 888******99999.7********************9988433 PP >> Pyr_redox_2 Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 2.6e-07 0.00043 135 178 .. 85 128 .. 67 135 .. 0.78 2 ? -3.9 0.0 5.8 9.9e+03 158 200 .. 425 468 .. 423 471 .. 0.88 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 2.6e-07 xxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Pyr_redox_2 135 alrlklkp...krlvvvGGGviGvElAaalaklgkeVtlveardrll 178 ++ p ++++++G+G++G+ +A++ a lg+ V+++e rdr+ FUN_000608-T1 85 YKNR---PcskSKVLIIGAGPCGLRIAIESALLGAYVVVIEKRDRFS 128 3333...2555999*****************************9986 PP == domain 2 score: -3.9 bits; conditional E-value: 5.8 xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Pyr_redox_2 158 Aaalaklgke.VtlveardrllraldkeisealekalekeGvev 200 A+ ++ lgke ++ rd ++r l + e + k +e+ G++ FUN_000608-T1 425 AMRAWGLGKEpLDILAERDSIYRLLAQTTPENISKNFEEFGINP 468 6778889999999999***********************99985 PP >> Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 6.5e-07 0.0011 1 30 [. 96 124 .. 96 137 .. 0.89 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 6.5e-07 Pyr_redox_3 1 iIiGaGPaGlaaaialkkagledylilEkg 30 +IiGaGP+Gl +ai+ +g ++++Ek FUN_000608-T1 96 LIIGAGPCGLRIAIESALLGA-YVVVIEKR 124 6*******************9.799***97 PP >> FAD_binding_2 FAD binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 2.8e-06 0.0048 2 35 .. 95 128 .. 94 133 .. 0.93 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 2.8e-06 FAD_binding_2 2 vvViGsGlAGLaAAleaaeaGlkvavvekgqstg 35 v++iG+G GL+ A+e a G+ v+v+ek ++++ FUN_000608-T1 95 VLIIGAGPCGLRIAIESALLGAYVVVIEKRDRFS 128 9****************************98875 PP >> CAMSAP_CH CAMSAP CH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 7.3e-06 0.012 13 70 .. 539 590 .. 525 601 .. 0.82 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 7.3e-06 CAMSAP_CH 13 vedllrdlsdGcaLaallhfYcPqliklediclketmSladslyNlqllqefcqekLg 70 ++d+ +G +a++h Y+P+li++++ + ++ l Nlql ++++e+Lg FUN_000608-T1 539 INDMSTSWKNGLGFCAIIHHYRPDLIDFSSLS------PKEHLANLQLAFDVAEEHLG 590 568888899*****************988766......78889999999999999985 PP >> HI0933_like HI0933-like protein Rossmann domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 7.9e-06 0.013 2 37 .. 94 129 .. 93 133 .. 0.94 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 7.9e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HI0933_like 2 dviviGgGaaGlmaaisaakagkkvlllekakklgr 37 +v++iG+G+ Gl ai+ a g+ v+++ek +++ r FUN_000608-T1 94 KVLIIGAGPCGLRIAIESALLGAYVVVIEKRDRFSR 129 79****************************999876 PP >> NAD_binding_8 NAD(P)-binding Rossmann-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 1e-05 0.018 1 32 [. 97 128 .. 97 131 .. 0.96 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1e-05 NAD_binding_8 1 IVGaGiaGlvaAalLakrglrvlllEkrdrlG 32 I+GaG++Gl +A + a g+ v+++Ekrdr++ FUN_000608-T1 97 IIGAGPCGLRIAIESALLGAYVVVIEKRDRFS 128 9****************************975 PP >> DAO FAD dependent oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 1.7e-05 0.028 1 35 [. 94 128 .. 94 167 .. 0.92 2 ? -2.8 0.1 2.8 4.7e+03 95 173 .. 1332 1404 .. 1316 1420 .. 0.62 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1.7e-05 DAO 1 dvvViGgGivGlstAyeLarrGlsVtllekgdepg 35 +v++iG+G Gl +A+e a G+ V+++ek+d+++ FUN_000608-T1 94 KVLIIGAGPCGLRIAIESALLGAYVVVIEKRDRFS 128 69*****************************8876 PP == domain 2 score: -2.8 bits; conditional E-value: 2.8 DAO 95 deeelealekllarakralgievelldaeelrelePlld..glkgalfypdggqvdpakllralaraaealGveilegtev 173 +++e ++l +++++ +r +e+ + ++ +le + + al++ ++g ++ + l+ + + ++ + i++++e FUN_000608-T1 1332 KQRESKRL-RMAQSIQR--ELEEVAVKQA---DLEK--EgiVVEKALRSGSTGGAEEHHLMLQWFKLVNRKNALIRFESEL 1404 34444444.34444323..1221124443...3333..1225668999999999988888888889999999999888775 PP >> Pyr_redox Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 6.5e-05 0.11 1 35 [. 94 128 .. 94 131 .. 0.94 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 6.5e-05 Pyr_redox 1 kvvvvGgGyiGlElAealarlgkkVtvverrdell 35 kv+++G+G Gl A a lg+ V v+e rd++ FUN_000608-T1 94 KVLIIGAGPCGLRIAIESALLGAYVVVIEKRDRFS 128 79******************************986 PP >> Lycopene_cycl Lycopene cyclase protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 4.1e-05 0.069 2 54 .. 95 146 .. 94 152 .. 0.87 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4.1e-05 Lycopene_cycl 2 vvviGaGpAglslAarlteakpglkvvlieaspsllfpnny.vWsdefedlgal 54 v++iGaGp gl++A ++ a g vv+ie + + n W + dl++l FUN_000608-T1 95 VLIIGAGPCGLRIAIES--ALLGAYVVVIEKRDRFSRNNVLhLWPFLIVDLKNL 146 89***************..************99998877656898887777665 PP >> AlaDh_PNT_C Alanine dehydrogenase/PNT, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00014 0.23 27 62 .. 91 126 .. 87 133 .. 0.89 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00014 AlaDh_PNT_C 27 epakvlviGgGvaGlnAaktAkglgakVtilDvrpa 62 +++kvl+iG+G Gl a ++ lga V ++++r + FUN_000608-T1 91 SKSKVLIIGAGPCGLRIAIESALLGAYVVVIEKRDR 126 578*************9999999*********9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1489 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1634 (0.0639656); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.57u 0.39s 00:00:00.96 Elapsed: 00:00:00.44 # Mc/sec: 13640.55 // Query: FUN_000609-T1 [L=292] Description: FUN_000609 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.26 12.1 1.4 0.53 11.1 1.4 1.4 1 YtxK_like YtxK N-terminal helical domain 0.34 11.2 0.5 0.73 10.2 0.5 1.5 1 Repressor_Mnt Regulatory protein Mnt Domain annotation for each model (and alignments): >> YtxK_like YtxK N-terminal helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 1.4 4.2e-05 0.53 30 75 .. 40 86 .. 30 88 .. 0.85 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 4.2e-05 YtxK_like 30 genlfqeevlqdeelselkkkrL..kkkyeeikleefskEeiRkafQL 75 enl+ +v ++ + +++++k+L +k+y+ +++++ +kE +k +QL FUN_000609-T1 40 IENLYASNVYHS-QRHAKQVKDLerQKHYSMLRMSNNQKEMFKKMMQL 86 59********96.666777777733689*******************9 PP >> Repressor_Mnt Regulatory protein Mnt # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.5 5.7e-05 0.73 6 18 .. 71 83 .. 70 84 .. 0.95 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 5.7e-05 Repressor_Mnt 6 RlADeqaElvKKt 18 R+ +q E++KK+ FUN_000609-T1 71 RMSNNQKEMFKKM 83 9***********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (292 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2143 (0.0838912); expected 510.9 (0.02) Passed bias filter: 758 (0.0296731); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 2812.73 // Query: FUN_000610-T1 [L=271] Description: FUN_000610 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (271 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 687 (0.0268937); expected 510.9 (0.02) Passed bias filter: 285 (0.0111568); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2674.29 // Query: FUN_000611-T1 [L=655] Description: FUN_000611 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-42 145.6 0.0 4.1e-42 144.9 0.0 1.4 1 Pkinase Protein kinase domain 6.7e-21 75.2 0.0 1.1e-20 74.6 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.0005 19.6 0.6 0.00081 19.0 0.6 1.2 1 Pox_ser-thr_kin Poxvirus serine/threonine protein kinase 0.0072 16.0 0.1 0.013 15.2 0.1 1.3 1 ABC1 ABC1 atypical kinase-like domain ------ inclusion threshold ------ 0.012 15.9 0.1 0.098 12.9 0.1 2.0 2 APH Phosphotransferase enzyme family 0.038 13.9 0.1 0.065 13.1 0.1 1.3 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.046 13.5 0.2 0.2 11.4 0.1 1.9 2 Kinase-like Kinase-like 0.047 13.8 0.1 0.082 13.0 0.1 1.3 1 RIO1 RIO domain Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 144.9 0.0 1.3e-45 4.1e-42 1 262 [] 91 391 .. 91 391 .. 0.83 Alignments for each domain: == domain 1 score: 144.9 bits; conditional E-value: 1.3e-45 Pkinase 1 yevleklGeGsfgkVykave..ketgkivAiKkikkekakkkke.kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkg 93 y+ ++ lG+G++++ + + + + +++ vA+K+++ ++ + + +r ++ lk + ++l+++f+ +d+++lv+E+v+ + l+++ +r + FUN_000611-T1 91 YKFMQVLGQGQSSVLIAVQDtfHPDKRPVAVKVMNLNNSYLGAQeAECVRKLNAADVLKVSRTIQLFNTFTFEDHYCLVFELVSSRPLHQYFQRCQ 186 78899******998765544225899*********9998877666899999999999999999*****************************9655 PP Pkinase 94 alsee....eakkilkqilegleylHsegvvHrDlKpeNiLid..ekgelKitDFGlakelesssk...ltsf.vgtseYmAPEvlkskkygkkvD 179 + +e+ ++ki+ q+++ l +l +++v+H DlKpeNiLi+ e+ ++K++DFG a + +++ +++f t Y+APEv+ + +g ++D FUN_000611-T1 187 FKDEDrklsVIRKIALQLVQVLGFLKRQNVIHADLKPENILIQggEDINIKVVDFGNALHCVDQEVslyYDDFeLQTLVYRAPEVMFGITFGLEID 282 55555777799********************************666667**********99998878996665268******************** PP Pkinase 180 vWslGvilyelltgkppfsaekekekvekeldqlekilki..........elkeklpepssi...........................seeakdl 238 +WslG+il+el+ g+ +f ++++k+ v ke+++++ + + + s + ++ FUN_000611-T1 283 MWSLGCILAELYIGECLFLGKTKKQ-VLKEVTTVFGPFPKnpfqsgkfihD----------FfefvgqnsesnkslcvtnmmkkllnsrSYAFSSF 367 *******************777666.3333344233332234443333330..........2555666677777778999999999999******* PP Pkinase 239 lkkllkkdpkkRltaeellqhpwf 262 l +ll+++p++Rlt ++ hp++ FUN_000611-T1 368 LVGLLQYNPNERLTPLQAAMHPFL 391 **********************96 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.6 0.0 3.4e-24 1.1e-20 2 218 .. 92 313 .. 91 324 .. 0.87 Alignments for each domain: == domain 1 score: 74.6 bits; conditional E-value: 3.4e-24 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtl..keeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrk 94 ++++ lG+G+ + + + + + +k +VavK++ ++++ +++e ++ ++ l+ ++ ++l t e+++++v+e+v++ L+++ ++ FUN_000611-T1 92 KFMQVLGQGQSSVLIAVQDT--FHPDKRPVAVKVMnlNNSYLGAQEAECVRKLNAADVLKVSRTIQLFNTFTFEDHYCLVFELVSSRPLHQYFQR 184 67899999997655554444..6677888888888446777888999*************************9*********************9 PP PK_Tyr_Ser-Thr 95 k...keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse..kkvvkisDfGLardvekddyy.kkkekaklpikWmapEslkekkfts 183 +e+ +l+ + k+alq+ + + +L++++++H dl N+L++ + +k+ DfG a + +++ + + ++ + + + apE++ +f FUN_000611-T1 185 CqfkDEDRKLSVIRKIALQLVQVLGFLKRQNVIHADLKPENILIQGgeDINIKVVDFGNALHCVDQEVSlYYDDFELQTLVYRAPEVMFGITFGL 279 8777777888888999****************************9633779*******99999666655466777778899************** PP PK_Tyr_Ser-Thr 184 ksDvWsfGvllwEiftlgeepykglkneevlelle 218 + D+Ws G +l E++ ge + g ++++vl+ ++ FUN_000611-T1 280 EIDMWSLGCILAELYI-GECLFLGKTKKQVLKEVT 313 **************98.999999999999998875 PP >> Pox_ser-thr_kin Poxvirus serine/threonine protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.6 2.5e-07 0.00081 281 343 .. 197 261 .. 178 266 .. 0.79 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 2.5e-07 Pox_ser-thr_kin 281 fLqiaLLyikiyelpscenflhvDlkPdniLifdskeklsik...vkerkyvfkepvklaLnDfDf 343 + +iaL ++++ +++n +h+DlkP+niLi e+++ik ++++ + +v l +Df++ FUN_000611-T1 197 IRKIALQLVQVLGFLKRQNVIHADLKPENILIQGG-EDINIKvvdFGNALHCVDQEVSLYYDDFEL 261 4579999999999999***************9765.455554112677888888889999999987 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.1 4e-06 0.013 177 221 .. 205 250 .. 158 264 .. 0.63 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 4e-06 ABC1 177 velfleqifedgffhaDphpGNllvrkdg..elvllDfGlmgeldek 221 v+ +l + +++++haD+ p N+l++ + ++ ++DfG ++ ++ FUN_000611-T1 205 VQ-VLGFLKRQNVIHADLKPENILIQGGEdiNIKVVDFGNALHCVDQ 250 22.2344567899*************77767999*****88766554 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.078 2.5e+02 38 104 .. 133 204 .. 113 207 .. 0.70 2 ? 12.9 0.1 3.1e-05 0.098 154 197 .. 196 244 .. 175 246 .. 0.68 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.078 APH 38 erelallrhLaaagvvpvPrvlagetdaellglpfllmeylpGedler.....nalseaeagalledlgeaL 104 ++e++ r L+aa+v++v r + + +++ +++l++e + ++l++ +e++ ++++++ L FUN_000611-T1 133 AQEAECVRKLNAADVLKVSRTIQLFNTFTFEDHYCLVFELVSSRPLHQyfqrcQFKDEDRKLSVIRKIALQL 204 6899999********999999876666666666555555555555444333777777777777777776666 PP == domain 2 score: 12.9 bits; conditional E-value: 3.1e-05 APH 154 llaallallpa....elppvlvHgDlhpgNllvd.dggrvsGviDFeda 197 +++ ++ +l + +++ ++H+Dl+p N+l++ +++ v+DF++a FUN_000611-T1 196 VIRKIALQLVQvlgfLKRQNVIHADLKPENILIQgGEDINIKVVDFGNA 244 444444444445555667889*************955555589***998 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.1 2e-05 0.065 102 168 .. 175 243 .. 132 251 .. 0.75 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2e-05 Kdo 102 aqdLedllaqwaelaeelrrallkavg....rlirklhragvqHgdlyakhillqtekeeeakasliDldk 168 + L+++ ++ + +e ++ +++++ ++ l r +v H+dl + +il+q ++ ++ + ++D+ FUN_000611-T1 175 SRPLHQYFQRCQFKDEDRKLSVIRKIAlqlvQVLGFLKRQNVIHADLKPENILIQGGE--DINIKVVDFGN 243 45677788875557777777777777731113445589*****************997..999999**965 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.27 8.6e+02 17 52 .. 94 129 .. 90 155 .. 0.86 2 ? 11.4 0.1 6.2e-05 0.2 141 240 .. 193 289 .. 133 323 .. 0.77 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.27 Kinase-like 17 gsllkkgdssvvflvtdqetgedlevhvflmkekps 52 ++l +g+ssv++ v+d +++ v v +m+ ++s FUN_000611-T1 94 MQVLGQGQSSVLIAVQDTFHPDKRPVAVKVMNLNNS 129 5899**************999999999999887776 PP == domain 2 score: 11.4 bits; conditional E-value: 6.2e-05 Kinase-like 141 sletlarlllTlqlirlaasLqskglvhgkfsvdnllld..ekggvflggfeaLvragtkvvsevekgfaPpEllgsrgg.lytrknktlmtfkld 233 +l + + lql+++ L+ + ++h++++++n+l++ e +++ +f++ + ++ vs f+ l ++ +++ +++ ++d FUN_000611-T1 193 KLSVI--RKIALQLVQVLGFLKRQNVIHADLKPENILIQggEDINIKVVDFGNALHCVDQEVSLYYDDFELQTLVYRAPEvMFG----ITFGLEID 282 34333..4578999***********************97446778899999988888888787777777776666665553333....47777888 PP Kinase-like 234 aWqlGlv 240 W lG FUN_000611-T1 283 MWSLGCI 289 8888854 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 2.6e-05 0.082 82 154 .. 167 247 .. 135 257 .. 0.71 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2.6e-05 RIO1 82 vlvmefig....kdgveapklkdve..eeeaeelyeevleemrklykeaglvHgDLseyNvlvded...kvviIDvsQavel 154 +lv e+++ ++ ++ ++ kd + + ++++ ++++ + ++k+++++H+DL N+l++ + ++ ++D++ a+++ FUN_000611-T1 167 CLVFELVSsrplHQYFQRCQFKDEDrkLSVIRKIALQLVQ-VLGFLKRQNVIHADLKPENILIQGGediNIKVVDFGNALHC 247 6777777722112233445555555332334555555555.778899****************9654266788999888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (655 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 676 (0.0264631); expected 510.9 (0.02) Passed bias filter: 561 (0.0219612); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 6477.80 // Query: FUN_000611-T2 [L=468] Description: FUN_000611 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-42 146.8 0.0 1.7e-42 146.2 0.0 1.3 1 Pkinase Protein kinase domain 3.1e-21 76.3 0.0 5e-21 75.6 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.00027 20.5 0.3 0.00041 19.9 0.3 1.2 1 Pox_ser-thr_kin Poxvirus serine/threonine protein kinase 0.0043 16.7 0.1 0.0077 15.9 0.1 1.4 1 ABC1 ABC1 atypical kinase-like domain 0.0053 17.0 0.1 0.067 13.4 0.1 2.1 2 APH Phosphotransferase enzyme family ------ inclusion threshold ------ 0.021 14.6 0.2 0.12 12.1 0.1 2.0 2 Kinase-like Kinase-like 0.023 14.6 0.1 0.039 13.9 0.1 1.3 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.029 14.5 0.1 0.048 13.7 0.1 1.3 1 RIO1 RIO domain Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 146.2 0.0 5.2e-46 1.7e-42 1 262 [] 91 391 .. 91 391 .. 0.83 Alignments for each domain: == domain 1 score: 146.2 bits; conditional E-value: 5.2e-46 Pkinase 1 yevleklGeGsfgkVykave..ketgkivAiKkikkekakkkke.kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkg 93 y+ ++ lG+G++++ + + + + +++ vA+K+++ ++ + + +r ++ lk + ++l+++f+ +d+++lv+E+v+ + l+++ +r + FUN_000611-T2 91 YKFMQVLGQGQSSVLIAVQDtfHPDKRPVAVKVMNLNNSYLGAQeAECVRKLNAADVLKVSRTIQLFNTFTFEDHYCLVFELVSSRPLHQYFQRCQ 186 78899******998765544225899*********9998877666899999999999999999*****************************9655 PP Pkinase 94 alsee....eakkilkqilegleylHsegvvHrDlKpeNiLid..ekgelKitDFGlakelesssk...ltsf.vgtseYmAPEvlkskkygkkvD 179 + +e+ ++ki+ q+++ l +l +++v+H DlKpeNiLi+ e+ ++K++DFG a + +++ +++f t Y+APEv+ + +g ++D FUN_000611-T2 187 FKDEDrklsVIRKIALQLVQVLGFLKRQNVIHADLKPENILIQggEDINIKVVDFGNALHCVDQEVslyYDDFeLQTLVYRAPEVMFGITFGLEID 282 55555777799********************************666667**********99998878996665268******************** PP Pkinase 180 vWslGvilyelltgkppfsaekekekvekeldqlekilki..........elkeklpepssi...........................seeakdl 238 +WslG+il+el+ g+ +f ++++k+ v ke+++++ + + + s + ++ FUN_000611-T2 283 MWSLGCILAELYIGECLFLGKTKKQ-VLKEVTTVFGPFPKnpfqsgkfihD----------FfefvgqnsesnkslcvtnmmkkllnsrSYAFSSF 367 *******************777666.3333344233332234443333330..........2555666677777778999999999999******* PP Pkinase 239 lkkllkkdpkkRltaeellqhpwf 262 l +ll+++p++Rlt ++ hp++ FUN_000611-T2 368 LVGLLQYNPNERLTPLQAAMHPFL 391 **********************96 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.6 0.0 1.6e-24 5e-21 2 218 .. 92 313 .. 91 325 .. 0.87 Alignments for each domain: == domain 1 score: 75.6 bits; conditional E-value: 1.6e-24 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtl..keeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrk 94 ++++ lG+G+ + + + + + +k +VavK++ ++++ +++e ++ ++ l+ ++ ++l t e+++++v+e+v++ L+++ ++ FUN_000611-T2 92 KFMQVLGQGQSSVLIAVQDT--FHPDKRPVAVKVMnlNNSYLGAQEAECVRKLNAADVLKVSRTIQLFNTFTFEDHYCLVFELVSSRPLHQYFQR 184 67899999997655554444..6677888888888446777888999*************************9*********************9 PP PK_Tyr_Ser-Thr 95 k...keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse..kkvvkisDfGLardvekddyy.kkkekaklpikWmapEslkekkfts 183 +e+ +l+ + k+alq+ + + +L++++++H dl N+L++ + +k+ DfG a + +++ + + ++ + + + apE++ +f FUN_000611-T2 185 CqfkDEDRKLSVIRKIALQLVQVLGFLKRQNVIHADLKPENILIQGgeDINIKVVDFGNALHCVDQEVSlYYDDFELQTLVYRAPEVMFGITFGL 279 8777777888888999****************************9633779*******99999666655466777778899************** PP PK_Tyr_Ser-Thr 184 ksDvWsfGvllwEiftlgeepykglkneevlelle 218 + D+Ws G +l E++ ge + g ++++vl+ ++ FUN_000611-T2 280 EIDMWSLGCILAELYI-GECLFLGKTKKQVLKEVT 313 **************98.999999999999998875 PP >> Pox_ser-thr_kin Poxvirus serine/threonine protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.3 1.3e-07 0.00041 281 344 .. 197 262 .. 175 266 .. 0.79 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 1.3e-07 Pox_ser-thr_kin 281 fLqiaLLyikiyelpscenflhvDlkPdniLifdskeklsik...vkerkyvfkepvklaLnDfDfs 344 + +iaL ++++ +++n +h+DlkP+niLi e+++ik ++++ + +v l +Df++ FUN_000611-T2 197 IRKIALQLVQVLGFLKRQNVIHADLKPENILIQGG-EDINIKvvdFGNALHCVDQEVSLYYDDFELQ 262 4579999999999999***************9765.4555541126778888888899999999875 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 2.4e-06 0.0077 173 221 .. 198 250 .. 156 264 .. 0.63 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.4e-06 ABC1 173 aeklvel..fleqifedgffhaDphpGNllvrkdg..elvllDfGlmgeldek 221 + ++l +l + +++++haD+ p N+l++ + ++ ++DfG ++ ++ FUN_000611-T2 198 RKIALQLvqVLGFLKRQNVIHADLKPENILIQGGEdiNIKVVDFGNALHCVDQ 250 3333333002344567899*************77767999*****88766554 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.043 1.4e+02 38 105 .. 133 205 .. 112 210 .. 0.71 2 ! 13.4 0.1 2.1e-05 0.067 154 197 .. 196 244 .. 176 246 .. 0.69 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.043 APH 38 erelallrhLaaagvvpvPrvlagetdaellgl...pfllmeylpGedler..nalseaeagalledlgeaLa 105 ++e++ r L+aa+v++v r + + +++ + +f l++ p +++ + +e++ ++++++ L+ FUN_000611-T2 133 AQEAECVRKLNAADVLKVSRTIQLFNTFTFEDHyclVFELVSSRPLHQYFQrcQFKDEDRKLSVIRKIALQLV 205 6899999********9999998766666666662225555555555555557777777777777777776665 PP == domain 2 score: 13.4 bits; conditional E-value: 2.1e-05 APH 154 llaallallpa....elppvlvHgDlhpgNllvd.dggrvsGviDFeda 197 +++ ++ +l + +++ ++H+Dl+p N+l++ +++ v+DF++a FUN_000611-T2 196 VIRKIALQLVQvlgfLKRQNVIHADLKPENILIQgGEDINIKVVDFGNA 244 444444444445555667889*************955555589***998 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 0.18 5.7e+02 17 52 .. 94 129 .. 90 154 .. 0.87 2 ? 12.1 0.1 3.7e-05 0.12 142 240 .. 194 289 .. 143 323 .. 0.76 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 0.18 Kinase-like 17 gsllkkgdssvvflvtdqetgedlevhvflmkekps 52 ++l +g+ssv++ v+d +++ v v +m+ ++s FUN_000611-T2 94 MQVLGQGQSSVLIAVQDTFHPDKRPVAVKVMNLNNS 129 5899**************999999999999887766 PP == domain 2 score: 12.1 bits; conditional E-value: 3.7e-05 Kinase-like 142 letlarlllTlqlirlaasLqskglvhgkfsvdnllld..ekggvflggfeaLvragtkvvsevekgfaPpEllgsrgg.lytrknktlmtfklda 234 l + + lql+++ L+ + ++h++++++n+l++ e +++ +f++ + ++ vs f+ l ++ +++ +++ ++d FUN_000611-T2 194 LSVI--RKIALQLVQVLGFLKRQNVIHADLKPENILIQggEDINIKVVDFGNALHCVDQEVSLYYDDFELQTLVYRAPEvMFG----ITFGLEIDM 283 3333..4578999***********************97446778999999988888888888777777777666665553343....477778888 PP Kinase-like 235 WqlGlv 240 W lG FUN_000611-T2 284 WSLGCI 289 888864 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.1 1.2e-05 0.039 102 168 .. 175 243 .. 131 251 .. 0.74 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.2e-05 Kdo 102 aqdLedllaqwaelaeelrrallkavg....rlirklhragvqHgdlyakhillqtekeeeakasliDldk 168 + L+++ ++ + +e ++ +++++ ++ l r +v H+dl + +il+q ++ ++ + ++D+ FUN_000611-T2 175 SRPLHQYFQRCQFKDEDRKLSVIRKIAlqlvQVLGFLKRQNVIHADLKPENILIQGGE--DINIKVVDFGN 243 56677888875557777777777777731113445589*****************997..999999**965 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 1.5e-05 0.048 82 154 .. 167 247 .. 134 257 .. 0.71 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.5e-05 RIO1 82 vlvmefig....kdgveapklkdve..eeeaeelyeevleemrklykeaglvHgDLseyNvlvded...kvviIDvsQavel 154 +lv e+++ ++ ++ ++ kd + + ++++ ++++ + ++k+++++H+DL N+l++ + ++ ++D++ a+++ FUN_000611-T2 167 CLVFELVSsrplHQYFQRCQFKDEDrkLSVIRKIALQLVQ-VLGFLKRQNVIHADLKPENILIQGGediNIKVVDFGNALHC 247 6777777722212333445555555332334555555555.778899****************9654266788999888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (468 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 540 (0.0211392); expected 510.9 (0.02) Passed bias filter: 472 (0.0184772); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 4673.67 // Query: FUN_000612-T1 [L=207] Description: FUN_000612 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-48 166.1 0.0 1.7e-48 165.7 0.0 1.1 1 ParcG Parkin co-regulated protein ------ inclusion threshold ------ 0.016 15.8 0.1 0.024 15.2 0.1 1.3 1 HEAT_GCN1 Stalled ribosome sensor GCN1-like, HEAT repeats 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 HEAT_EF3_N EF3 N-terminal HEAT repeat 0.22 10.5 0.0 0.28 10.1 0.0 1.1 1 RRN3 RNA polymerase I specific transcription initiatio Domain annotation for each model (and alignments): >> ParcG Parkin co-regulated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 165.7 0.0 2.7e-52 1.7e-48 1 183 [] 37 204 .. 37 204 .. 0.97 Alignments for each domain: == domain 1 score: 165.7 bits; conditional E-value: 2.7e-52 ParcG 1 tsFravYdrGdlpirvehgskkkkiqWkveiekLdydalLplffdGLretkhpyrflAregikdllea.ageekilpvlpklilplkkaLntrdee 95 +sF+a Y +G++p+r+ hgs+k+++qW++++e+L++d++L+++++GL+etkhpy+f+Areg++++le ++ + lp+l kl++pl+ aL + d+e FUN_000612-T1 37 SSFAASYTNGGVPCRLVHGSVKHRLQWSTSPENLPFDPVLVTLAEGLQETKHPYTFVAREGFREMLEVdDAALRTLPLLGKLVVPLRVALASPDSE 132 68*****************************************************************988999*********************** PP ParcG 96 viesaLkvlqklvksseligeaLvpyyrqlLpvlnlfknkrvnlgdkidyrkkknlkdliqetlellerngGedalinIkymiPtYes 183 v++s+L+++ +l s ++g++L+p++++lLp ++ kr ++k k+ i ++l+ le+n+G+++ +Ik++iPtY+s FUN_000612-T1 133 VFHSSLEAMVQL---SAVVGPSLNPHLKALLPQVS----KR---------FMDKTHKERILHALQRLEQNVGKESVPIIKSKIPTYQS 204 *********999...********************....77.........5677889*****************************98 PP >> HEAT_GCN1 Stalled ribosome sensor GCN1-like, HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 3.8e-06 0.024 18 73 .. 137 187 .. 118 199 .. 0.76 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 3.8e-06 HEAT_GCN1 18 nakaLasLaevaGeaLnrhLskilpaLlsalseeeeedeeeeeeleeaaeavvlsv 73 + +a+ L++v G++Ln hL+ +lp + + + +++ +e + +a++ + ++v FUN_000612-T1 137 SLEAMVQLSAVVGPSLNPHLKALLPQVSKRFMDKTH-----KERILHALQRLEQNV 187 4578999*********************99997663.....334444444444444 PP >> HEAT_EF3_N EF3 N-terminal HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 3.5e-05 0.23 47 92 .. 140 183 .. 116 199 .. 0.73 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.5e-05 HEAT_EF3_N 47 aaiaseselspsvEPylvellpellelvgDkkkevkeaaeeaakai 92 a+++ ++ ++ps+ P+l +llp++ +++ Dk ++ e a++ + FUN_000612-T1 140 AMVQLSAVVGPSLNPHLKALLPQVSKRFMDKTHK--ERILHALQRL 183 556667789*********************9874..4444455555 PP >> RRN3 RNA polymerase I specific transcription initiation factor RRN3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 4.4e-05 0.28 462 508 .. 142 189 .. 116 204 .. 0.85 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 4.4e-05 RRN3 462 kvlqrvilskLnP.LkvCspnvveeFakiakhlqllycfsilesnkre 508 +l+ v+ LnP Lk +p+v + F ++++++l + le+n + FUN_000612-T1 142 VQLSAVVGPSLNPhLKALLPQVSKRFMDKTHKERILHALQRLEQNVGK 189 489999**************************************9765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (207 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 735 (0.0287728); expected 510.9 (0.02) Passed bias filter: 685 (0.0268154); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.44s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2066.02 // Query: FUN_000613-T1 [L=1874] Description: FUN_000613 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-07 29.1 0.1 6e-06 26.6 0.0 2.3 2 DEP Domain found in Dishevelled, Egl-10, and Pleckst 0.00018 21.1 6.9 0.065 12.7 0.1 3.1 3 MUN MUN domain ------ inclusion threshold ------ 0.11 11.7 0.0 0.29 10.4 0.0 1.6 1 TPR_PATROL1 PATROL1-like, TPR repeats Domain annotation for each model (and alignments): >> DEP Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.1 0.65 5.5e+03 7 18 .. 1499 1510 .. 1495 1511 .. 0.89 2 ! 26.6 0.0 7e-10 6e-06 7 57 .. 1635 1692 .. 1632 1698 .. 0.92 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.65 DEP 7 rrkhlktypncf 18 rr h yp+cf FUN_000613-T1 1499 RRFHSVLYPDCF 1510 8999*******9 PP == domain 2 score: 26.6 bits; conditional E-value: 7e-10 DEP 7 rrkhlktypncftGseavdWLldnle.......iktreeAvelgqkLlekgliehvtd 57 rk+l t+++cf+G+e+v+WL + ++ + +velgq +le+g+++ vt FUN_000613-T1 1635 LRKDLHTIRKCFSGAELVEWLENYVRengledfGSYIGSGVELGQYMLEQGIVTCVTS 1692 5899*************************9999888899**************99986 PP >> MUN MUN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.1 7.7e-06 0.065 56 179 .. 537 659 .. 509 677 .. 0.81 2 ? 0.7 0.2 0.033 2.8e+02 181 250 .. 1216 1288 .. 1178 1308 .. 0.76 3 ! 9.8 0.1 5.7e-05 0.49 342 471 .. 1481 1592 .. 1455 1594 .. 0.85 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 7.7e-06 MUN 56 LieLivsvleedkesyaevleafpqeldlgkesaetfwslfavdmdaaLeeqeqe..klcksdeymslhFkvkqLlnnylkddpalkhavpelpdl 149 +i+L+ ++ e k+ + + eaf++++d+++ +f+sl+ +d+++ e+ + +++ l F++ L +++ k +p ++ +++++ FUN_000613-T1 537 MIKLVFEIRREVKQYNSFYNEAFSSYFDVMERGTFQFYSLLMSDIEQLCENPPRAhkPGGVETDLLCLAFRLSNLDKDWSKFIP-FSL--QKWREP 629 57778887777777667778***************************999874431133456788899**********988776.555..79**** PP MUN 150 Feplvvryldenesviaeslhkaferdkwe 179 F+ + +++ld +++ + + + d+w+ FUN_000613-T1 630 FKRFALQWLDAINHSFRALVPQMISCDSWT 659 **********99998877777777777776 PP == domain 2 score: 0.7 bits; conditional E-value: 0.033 MUN 181 dgfqkssehalfsssvedvftkLdqlfeiik...kLecPdpelakhlekrlkktiskvleayvkrlkkafekk 250 +g +++s+ +sss +dv++ + l +++ k+ cP+ + +k+ ++ l ++v++l k + FUN_000613-T1 1216 EGKHEASQVFPISSSFVDVLCAVNRLASFVChlcKILCPEGLQQDEKSMTMKRELCDKLIQVVNLLVKLYSDS 1288 444566666777*****************97222557999887777777788888888888887777766554 PP == domain 3 score: 9.8 bits; conditional E-value: 5.7e-05 MUN 342 ydedsllssllslLdgslslFarkcektvlkrvlkelwklvlktlektvvlPplsdkkvillvkklekeeeknlspkqCavldvaletikqyfy 435 yd + l++ l++L +l +F+ +r+l+e+w + + ++ ++ + + + ++k C +l a ++++ f+ FUN_000613-T1 1481 YDIRKRLKPALHFLTCELRRFHSVLYPDCFNRLLNEVW-V---------------SVAEMFKEELSRLAKRRASASKHCELLLEAEAYLMKFFH 1558 6777889999****************************.2...............223334455566677788889****************** PP MUN 436 aggnglkktfLekslelqllrYaLslltqitdklik 471 a+++gl + e s l +l+ L+l+t tdkli+ FUN_000613-T1 1559 AQNSGLGCD--EMSATLGSLQKELQLYTLPTDKLIT 1592 ********9..77889999999***********997 PP >> TPR_PATROL1 PATROL1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 3.4e-05 0.29 249 382 .. 1485 1616 .. 1480 1632 .. 0.83 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 3.4e-05 TPR_PATROL1 249 sriepalreLkqnLellssivtdrvrtrvvtevmkAsfdafllVLLaGGpsRaFtrqDseiieeDfksLkelFlanGdGLvaeevvekeaetve 342 +r++pal+ L +L+ s++ +r+++ev+ + + f L + Ra + e++ e + L ++F a+ GL +e+ + ++ FUN_000613-T1 1485 KRLKPALHFLTCELRRFHSVLYPDCFNRLLNEVWVSVAEMFKEELSRLAKRRASASKHCELLLEAEAYLMKFFHAQNSGLGCDEMSATLGS-LQ 1577 79******************************************************************************98776655555.66 PP TPR_PATROL1 343 gvlaLmsldteqLiedfkialelegigssaksklplpptt 382 + l+L+ l+t++Li+ +++ ++ ++s+ ++ ++ ++t FUN_000613-T1 1578 KELQLYTLPTDKLITLYNSYFTQYLRTQSE-NQADVHAST 1616 779**************9876655544433.333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1874 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 964 (0.0377373); expected 510.9 (0.02) Passed bias filter: 619 (0.0242317); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.54u 0.42s 00:00:00.96 Elapsed: 00:00:00.42 # Mc/sec: 18184.46 // Query: FUN_000614-T1 [L=614] Description: FUN_000614 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-26 92.4 0.2 1e-21 77.6 0.1 2.6 2 Beta-prop_THOC3 THOC3 beta-propeller domain 5.4e-26 92.0 0.5 3.3e-10 40.2 0.1 3.4 3 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 1.2e-24 87.6 1.1 1.7e-12 47.7 0.0 3.6 3 Beta-prop_WDR5 WDR5 beta-propeller domain 1.5e-21 77.4 1.4 2.8e-09 37.0 0.1 3.9 3 WD40_WDHD1_1st WDHD1 first WD40 domain 1.8e-19 70.3 0.0 1e-09 38.3 0.0 3.5 2 WD40_Prp19 Prp19 WD40 domain 1.1e-18 67.3 18.0 0.00015 22.7 0.3 7.6 8 WD40 WD domain, G-beta repeat 1.7e-18 67.4 0.1 1.3e-09 38.5 0.0 3.6 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 6.2e-17 62.3 0.2 5.3e-07 29.8 0.0 4.4 4 Beta-prop_EML_2 Echinoderm microtubule-associated 9.3e-16 58.4 5.8 4e-07 30.0 0.1 4.3 4 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 3.3e-13 50.2 0.7 8.4e-08 32.5 0.1 3.4 2 Beta-prop_EML Echinoderm microtubule-associated 8.1e-12 45.3 0.1 9.4e-05 22.1 0.1 3.4 3 WDR55 WDR55 2.3e-11 44.0 0.7 9.9e-07 28.7 0.0 4.0 4 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 1.5e-10 41.6 0.0 0.002 18.8 0.0 4.2 4 ANAPC4_WD40 Anaphase-promoting complex subunit 5.1e-10 39.4 10.8 6.8e-07 29.2 1.0 3.0 4 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 6.3e-09 35.7 0.0 0.00059 19.4 0.0 3.4 3 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 8.1e-09 35.7 0.0 0.00061 19.6 0.0 3.0 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 1.5e-07 31.6 0.9 0.014 15.3 0.0 5.1 6 Beta-prop_RIG_2nd RIG second beta-propeller 2.4e-07 30.9 0.0 0.00016 21.7 0.0 3.0 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 7.6e-07 29.0 0.7 0.006 16.2 0.0 3.3 3 WDR90_beta-prop_4th WDR90, 4th beta-propeller 2.5e-06 27.3 8.6 0.0064 16.1 0.0 5.0 5 EIF3I EIF3I 4.5e-06 26.1 0.4 0.67 9.1 0.0 4.8 4 Beta-prop_IFT140_1st IFT140 first beta-propeller 5.6e-06 26.1 0.1 0.068 12.6 0.1 2.4 2 Ge1_WD40 WD40 region of Ge1, enhancer of mR 2.4e-05 23.9 0.1 0.22 10.8 0.0 3.3 3 NBCH_WD40 Neurobeachin beta propeller domain 2.7e-05 23.7 0.7 0.0078 15.6 0.1 3.4 3 Beta-prop_IP5PC_F IP5P C-F beta-propeller 9.5e-05 22.0 1.8 0.14 11.7 0.1 2.6 2 WD40_Gbeta G protein beta WD-40 repeat protei 0.00011 21.8 1.5 0.17 11.3 0.0 4.3 5 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 0.00018 21.4 7.7 0.015 15.2 0.0 3.7 4 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 0.00048 20.0 0.7 0.18 11.6 0.0 3.2 3 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 0.0014 18.2 0.0 0.044 13.3 0.0 3.0 3 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.0026 17.5 0.0 0.058 13.0 0.0 2.5 2 PROPPIN PROPPIN 0.0068 15.9 1.4 0.17 11.3 0.0 3.1 4 WD_LRWD1 Leucine-rich repeat and WD repeat- 0.0075 16.0 3.2 13 5.4 0.0 3.7 4 Beta-prop_HPS5 HPS5 beta-propeller 0.0083 15.8 0.0 0.0083 15.8 0.0 3.8 3 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 0.0095 16.3 0.0 2.5 8.4 0.0 3.8 4 eIF2A Eukaryotic translation initiation ------ inclusion threshold ------ 0.022 15.2 0.1 0.21 12.1 0.0 2.8 1 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 0.035 13.1 0.0 0.37 9.8 0.0 2.4 3 Cytochrom_D1 Cytochrome D1 heme domain 0.036 13.4 0.1 0.49 9.7 0.0 2.5 3 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 0.15 12.7 5.6 0.38 11.4 5.6 1.8 1 Caudo_TAP Caudovirales tail fibre assembly p 1.9 7.8 13.8 2.8 7.3 13.8 1.2 1 eIF-3_zeta Eukaryotic translation initiation 5.1 6.1 12.9 17 4.4 10.7 2.4 2 WD40_2 WD40 repeated domain Domain annotation for each model (and alignments): >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.6 0.1 1.6e-24 1e-21 1 255 [. 265 514 .. 265 520 .. 0.82 2 ! 15.5 0.0 1.4e-05 0.0092 86 197 .. 490 608 .. 487 611 .. 0.78 Alignments for each domain: == domain 1 score: 77.6 bits; conditional E-value: 1.6e-24 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgen... 91 h++++ + +s++G+++ s+ aD +v+vwn++ + + ++ ++ +l+w p+++ ll + +v+++d++++k + v+t++++ FUN_000614-T1 265 HHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDIHTCAS--VMLKSPLLSLEWAPKQDRLLLLGTGNGKVKFYDTENKKIICDVSTESQYprv 356 78889999***********************999776643..345799***************************************9986454 PP Beta-prop_THOC3 92 inlawspdGktiavgskddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgdgtvevlsypsleevktlkaht..snclcvafdpkg 183 ++l+ sp G +++ ++ + +++ +++ ne++ ++++ +++ + g +++++++ ++ ++l+ + + c a + +g FUN_000614-T1 357 VSLSCSPTGGAFVCSAAA-------SKKSSSSSSRLSQSRSNEMSSMSSSS--ITGGSGGVLQCWDMKLMKLERQLRLEPlpTCINCTAYNHNG 441 89******9988887764.......35555555555666777776544444..567788999****99887777766665115667******** PP Beta-prop_THOC3 184 rylAvGsaDalvslWDleeliclrtltrlespvrsvsFShdGkllAsased.ktidiasvetgesvhtiktea 255 ++ +G+aD +++l+D++++ cl+ + ++e ++ s++FS d +++ s ++d k+i+ + + g++++ ++ ++ FUN_000614-T1 442 TLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDgKFIQWSVHRMGKRIADLEIQE 514 ******************************************9998776552889888888899998888765 PP == domain 2 score: 15.5 bits; conditional E-value: 1.4e-05 Beta-prop_THOC3 86 ktkgeninlawspdGktiavgskddtvslidvrtgkv.kkeekf..kkevnevafspdgkllllt.tgdgtve.vlsypsleevktlkahtsnc 174 t+g+ i+ + + Gk ia + ++ v +++++ ++++k+ ++ + +af+ +g++ll++ t++g v+ v + + l++v +l h+s + FUN_000614-T1 490 GTDGKFIQWSVHRMGKRIADLEIQEGVVWCETDGAGYsQSRYKYspSSYGKMFAFDAEGQYLLTCgTESGAVHkVGKNHGLRQVLSLPEHKSPV 583 6788889999999999999999999999999987544144455521455678********888654888888724466789************* PP Beta-prop_THOC3 175 lcvafdpkgr..ylAvGsaDalvsl 197 ++v+++ + + +Gs D ++++ FUN_000614-T1 584 VSVDWSSLQScyTCLTGSVDGTIQV 608 ******9876336789999999976 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.2 0.1 5.2e-13 3.3e-10 127 246 .. 258 378 .. 237 400 .. 0.86 2 ! 39.3 0.1 1e-12 6.4e-10 63 167 .. 397 503 .. 375 517 .. 0.80 3 ! 9.4 0.0 0.0013 0.83 52 117 .. 537 608 .. 514 613 .. 0.66 Alignments for each domain: == domain 1 score: 40.2 bits; conditional E-value: 5.2e-13 WD40_CDC20-Fz 127 vvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgs 222 +++++++h++ + +++s++gr++ s d+ vk+w+ + + k+ l+W p + lL G G+ +++++++t+++k++ +v+t+s FUN_000614-T1 258 SQDSYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQDRLLLLGTGN--GKVKFYDTENKKIICDVSTES 351 4568899*******************************987777767779********************996..9******************** PP WD40_CDC20-Fz 223 q...vtsllwskeekelvsthgysknq 246 q v sl s++ +v++ sk++ FUN_000614-T1 352 QyprVVSLSCSPTGGAFVCSAAASKKS 378 988899999999999999888877654 PP == domain 2 score: 39.3 bits; conditional E-value: 1e-12 WD40_CDC20-Fz 63 gelLavGtssgevelwdvekkkklrtlegh..ssrvgalawnenl..lssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrllAsGg 154 ++ ++G s g +++wd++ +k r+l+ + + +++ a n+n +sG dg i+ +D+r+ + + + + ah++e+c+l++s+d++++ s g FUN_000614-T1 397 SSSSITGGSGGVLQCWDMKLMKLERQLRLEplPTCINCTAYNHNGtlCISGGADGMIRLFDMRSFD--CLNGWLAHEGEICSLQFSADETTVYSMG 490 3334689999************9999987633578999999877433699**************98..568899********************** PP WD40_CDC20-Fz 155 ndntvkiwdlrsl 167 d++ w+++ + FUN_000614-T1 491 TDGKFIQWSVHRM 503 *****99998765 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0013 WD40_CDC20-Fz 52 dyvtsvkwsedge.lLavGtssgevelwdvekk.kklrtleghssrvgalaw....nenllssGsrdgkilh 117 +y +++ +g+ lL +Gt+sg v+ + +++ +++ +l +h+s v +++w ++ + ++Gs dg+i++ FUN_000614-T1 537 SYGKMFAFDAEGQyLLTCGTESGAVHKVGKNHGlRQVLSLPEHKSPVVSVDWsslqSCYTCLTGSVDGTIQV 608 555666777666624567888888877666655366778888888888888844333345778888888765 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.0 7.3e-09 4.7e-06 130 232 .. 264 366 .. 261 373 .. 0.45 2 ! 47.7 0.0 2.7e-15 1.7e-12 64 162 .. 401 501 .. 389 515 .. 0.85 3 ! 8.2 0.0 0.0029 1.8 98 158 .. 544 608 .. 536 612 .. 0.51 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 7.3e-09 Beta-prop_WDR5 130 aHsdpvsavdfnrdgtlivsssyDgliriwdte..tgqclktlveddnppvsfvkFspng.kyiLastldstirLwdyekekvvktYkghkneky 221 H+ ++ +f+++g+++ s+ Dg++++w+ + +c ++ ++p+ + +++p++ + +L t + +++ +d+e++k++ + +++ FUN_000614-T1 264 EHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHpdIHTCASVML---KSPLLSLEWAPKQdRLLLLGTGNGKVKFYDTENKKIICDVSTESQYPR 355 35555555555555555555555555555554311233444443...345555555554313455555555555555555555544444444333 PP Beta-prop_WDR5 222 cisaefsetgg 232 ++s + s tgg FUN_000614-T1 356 VVSLSCSPTGG 366 33333334444 PP == domain 2 score: 47.7 bits; conditional E-value: 2.7e-15 Beta-prop_WDR5 64 asaSDDktvriwdvetgkllktl..kgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgli 156 +++ ++ wd++ kl ++l + ++ c+a+n++g+l +SG++D ++rl+d+r+ cl+ aH+ +++++f+ d t++ s +Dg FUN_000614-T1 401 ITGGSGGVLQCWDMKLMKLERQLrlEPLPTCINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKF 495 555556678999999887666551156789***************************************************************99 PP Beta-prop_WDR5 157 riwdte 162 w ++ FUN_000614-T1 496 IQWSVH 501 888765 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0029 Beta-prop_WDR5 98 FnpkgnllvSGsfDe.tvr.lWdvrtgkclktlpaHsdpvsavdfnrdgt..livsssyDgliri 158 F+++g+ l++++++ +v+ + + + + + +lp H+ pv +vd+++ + + +++s+Dg+i++ FUN_000614-T1 544 FDAEGQYLLTCGTESgAVHkVGKNHGLRQVLSLPEHKSPVVSVDWSSLQScyTCLTGSVDGTIQV 608 44444444444333212220222222244455677777777777766555334566777777665 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.0 0.1 4.4e-12 2.8e-09 121 244 .. 259 376 .. 238 403 .. 0.88 2 ! 30.0 0.0 6.2e-10 3.9e-07 87 159 .. 430 502 .. 393 543 .. 0.87 3 ? 6.3 0.1 0.01 6.4 95 154 .. 545 608 .. 536 613 .. 0.70 Alignments for each domain: == domain 1 score: 37.0 bits; conditional E-value: 4.4e-12 WD40_WDHD1_1st 121 qktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlpksndfsaskslcrlawepksgkllavPvek.evklyerdtweeaf 214 q ++++h +++ ++++++g ++ S++ DG vk+W+ + ++++ +++ ++ l l+w pk+++ll + +++ +vk+y++++ + ++ FUN_000614-T1 259 QDSYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPD--------IHTCASVMLKSPLLSLEWAPKQDRLLLLGTGNgKVKFYDTENKKIIC 345 56789*******************************9854........6679999******************999966648************* PP WD40_WDHD1_1st 215 klsknklsedisivafSpcG.kylaaatvdg 244 +s+++ + ++ Sp+G ++ +a+ ++ FUN_000614-T1 346 DVSTESQYPRVVSLSCSPTGgAFVCSAAASK 376 **99999977777888888758888887655 PP == domain 2 score: 30.0 bits; conditional E-value: 6.2e-10 WD40_WDHD1_1st 87 apvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdies 159 + +++ a++++g+l+++g++D +i++ +++ + h++ + s+++++ + ++ S ++DG+ W++ FUN_000614-T1 430 TCINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSVHR 502 5589*************************9999999999******************************9974 PP == domain 3 score: 6.3 bits; conditional E-value: 0.01 WD40_WDHD1_1st 95 skdgkl.laagseDftikvvsveds.skqktleghkapvlsvaldpkge..ylaSsscDGtvki 154 +++g++ l +g+e ++ v + + ++++l +hk+pv sv+ ++ + + + s+DGt+++ FUN_000614-T1 545 DAEGQYlLTCGTESGAVHKVGKNHGlRQVLSLPEHKSPVVSVDWSSLQScyTCLTGSVDGTIQV 608 5555541456777777777765444256778999999999999999885214568899999987 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.0 2.7e-08 1.7e-05 44 153 .. 261 371 .. 258 379 .. 0.85 2 ! 38.3 0.0 1.6e-12 1e-09 109 274 .. 403 594 .. 401 603 .. 0.79 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.7e-08 WD40_Prp19 44 tlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgd.ylvsaskDgtwalhdletgktllkvkdeeskeai 138 ++++h+ ++ +++f+++ +++ sa aD+ v+vw+ + + + + k+ sl+ p +d +l+ + +g+++++d e++k++++v+ e++ ++ FUN_000614-T1 261 SYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQDrLLLLGTGNGKVKFYDTENKKIICDVSTESQYPRV 356 56799*****************************977644444456899*********987256788899*******************9999999 PP WD40_Prp19 139 tsaqfHPDGlllgtG 153 s++ P G + + FUN_000614-T1 357 VSLSCSPTGGAFVCS 371 999999999766555 PP == domain 2 score: 38.3 bits; conditional E-value: 1.6e-12 WD40_Prp19 109 askDgtwalhdletgktllkvkdeeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsasedgtvklW 204 +++ g+++ +d++ k ++++ e + i++ ++ +G+l+ G +dg+++++D++s +++ +h+g++ sl+FS + + s +dg+ W FUN_000614-T1 403 GGSGGVLQCWDMKLMKLERQLRLEPLPTCINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQW 498 566677777888888888888888888899************************************************************999999 PP WD40_Prp19 205 DL.Rklknfktleld.....................eeskvnsvaFDksgqyLavagsd.vrvyev...kkweelatledhtaevtsvafgpdaks 274 R k ++ le++ +s + aFD gqyL ++g++ v++v + +++++l +h++ v sv++++ ++ FUN_000614-T1 499 SVhRMGKRIADLEIQegvvwcetdgagysqsrykysPSSYGKMFAFDAEGQYLLTCGTEsGAVHKVgknHGLRQVLSLPEHKSPVVSVDWSSLQSC 594 98466799*****9755555555555554433322122345779*********9987764667765322568899****************97653 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.3 2.3e-07 0.00015 6 39 .] 261 294 .. 257 294 .. 0.90 2 ? 0.9 0.0 1.8 1.1e+03 14 39 .] 311 337 .. 302 337 .. 0.73 3 ? -0.3 0.1 4.4 2.8e+03 14 29 .. 356 371 .. 347 377 .. 0.77 4 ? -0.9 0.2 6.7 4.3e+03 27 39 .] 401 413 .. 389 413 .. 0.78 5 ! 19.7 0.0 2e-06 0.0013 13 39 .] 431 457 .. 425 457 .. 0.93 6 ! 10.5 0.1 0.0017 1.1 3 39 .] 463 499 .. 461 499 .. 0.83 7 ? 1.5 0.0 1.2 7.4e+02 18 30 .. 543 555 .. 541 562 .. 0.84 8 ! 16.9 0.2 1.6e-05 0.01 3 37 .. 572 608 .. 570 610 .. 0.89 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 2.3e-07 WD40 6 tlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +++ H s++ ++fs++g+++ s+++Dg vk+W+ FUN_000614-T1 261 SYREHHSAIVHCRFSSNGRMVGSADADGIVKVWN 294 5677879999**************9********7 PP == domain 2 score: 0.9 bits; conditional E-value: 1.8 WD40 14 Vtslafspdgsl..lasgsdDgtvklWd 39 sl + p + l g +g+vk++d FUN_000614-T1 311 LLSLEWAPKQDRllL-LGTGNGKVKFYD 337 567777777777423.5766******98 PP == domain 3 score: -0.3 bits; conditional E-value: 4.4 WD40 14 Vtslafspdgsllasg 29 V sl+ sp+g ++++ FUN_000614-T1 356 VVSLSCSPTGGAFVCS 371 7899999999988743 PP == domain 4 score: -0.9 bits; conditional E-value: 6.7 WD40 27 asgsdDgtvklWd 39 ++g+ g + +Wd FUN_000614-T1 401 ITGGSGGVLQCWD 413 47877*******9 PP == domain 5 score: 19.7 bits; conditional E-value: 2e-06 WD40 13 gVtslafspdgsllasgsdDgtvklWd 39 +++ a++++g+l +sg++Dg ++l+d FUN_000614-T1 431 CINCTAYNHNGTLCISGGADGMIRLFD 457 499**********************98 PP == domain 6 score: 10.5 bits; conditional E-value: 0.0017 WD40 3 llrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +l + +H++ ++sl fs d + ++s + Dg+ W+ FUN_000614-T1 463 CLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWS 499 6666679*999*************9745599998885 PP == domain 7 score: 1.5 bits; conditional E-value: 1.2 WD40 18 afspdgsllasgs 30 af+ g++l++++ FUN_000614-T1 543 AFDAEGQYLLTCG 555 7999******996 PP == domain 8 score: 16.9 bits; conditional E-value: 1.6e-05 WD40 3 llrtlkgHtsgVtslafspdgsl..lasgsdDgtvkl 37 ++ +l+ H+s+V s+++s+ s ++gs Dgt+ + FUN_000614-T1 572 QVLSLPEHKSPVVSVDWSSLQSCytCLTGSVDGTIQV 608 67899***999*****999999999789*******87 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 1.7e-06 0.0011 110 183 .. 263 337 .. 258 376 .. 0.64 2 ! 38.5 0.0 2e-12 1.3e-09 11 102 .. 409 502 .. 399 519 .. 0.87 3 ? 5.4 0.0 0.03 19 77 139 .. 542 608 .. 537 613 .. 0.62 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 1.7e-06 Beta-prop_WDR3_1st 110 kgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskde.kllvtgssdselrvwk 183 + H++++ +++f+++++++ s+ D ++k+W+ + v +s sl+ +++ +ll+ g+ + ++++++ FUN_000614-T1 263 REHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQdRLLLLGTGNGKVKFYD 337 456666666666666666666666666666666666555555566666666666654313455666666666664 PP == domain 2 score: 38.5 bits; conditional E-value: 2e-12 Beta-prop_WDR3_1st 11 vlvWdlkkgekvatl..egeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwD 99 + +Wd+k + ++l e + +++ a +++g+ + +G adg+irl+d++s ++ + +H++++ +l+f++d++++ s ++D + i w FUN_000614-T1 409 LQCWDMKLMKLERQLrlEPLPTCINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWS 499 578**999877766622667899*****************************************************************999 PP Beta-prop_WDR3_1st 100 vva 102 v + FUN_000614-T1 500 VHR 502 864 PP == domain 3 score: 5.4 bits; conditional E-value: 0.03 Beta-prop_WDR3_1st 77 lafdkdgsrLasGskDtdiivwDvvaeag...lfrLkgHkdqvtsvafle..ekkvlvssSkDtlikl 139 afd++g+ L ++++++ v v ++ g + L Hk++v sv +++ + + +++S D +i++ FUN_000614-T1 542 FAFDAEGQYLLTCGTESG-AVHKVGKNHGlrqVLSLPEHKSPVVSVDWSSlqSCYTCLTGSVDGTIQV 608 577777777777777665.3455555544111456778888888887765114446778888887765 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.1 0.0024 1.5 119 152 .. 261 294 .. 255 297 .. 0.83 2 ! 15.2 0.0 2.3e-05 0.014 16 95 .. 284 367 .. 281 381 .. 0.79 3 ! 29.8 0.0 8.3e-10 5.3e-07 40 168 .. 386 516 .. 367 523 .. 0.64 4 ! 8.6 0.0 0.0024 1.5 88 142 .. 543 598 .. 534 610 .. 0.77 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0024 Beta-prop_EML_2 119 klkghssfithlDwsedskylqsnsgdyellfwd 152 ++++h+s+i+h+ +s++++++ s ++d+ + +w+ FUN_000614-T1 261 SYREHHSAIVHCRFSSNGRMVGSADADGIVKVWN 294 6788999999999999999999999999888887 PP == domain 2 score: 15.2 bits; conditional E-value: 2.3e-05 Beta-prop_EML_2 16 agdDktvrlWdle.kkklvakvklekearsvafspdgk.llavGlkdGsvlvldaetleevvevkdrke..aisdikfspdgkl 95 a D++v +W+++ + + a+v l++++ s+++ p+++ ll +G+ +G+v +d+e+ + + v+++++ ++ +++sp g FUN_000614-T1 284 ADADGIVKVWNYHpDIHTCASVMLKSPLLSLEWAPKQDrLLLLGTGNGKVKFYDTENKKIICDVSTESQypRVVSLSCSPTGGA 367 5679*******98346788999************98763789*****************9998766554227777778887644 PP == domain 3 score: 29.8 bits; conditional E-value: 8.3e-10 Beta-prop_EML_2 40 kearsvafspdgkllavGlkdGsvlvldae..tleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskkykkvgklkghssfithlD 131 ++ rs ++s+ + + G + G + ++d + +le+ +++ + i++ +++++g+l g +d++i l+d+ ++++ ++ h+ i +l FUN_000614-T1 386 SQSRSNEMSSMSSSSITGGSGGVLQCWDMKlmKLERQLRLEPLPTCINCTAYNHNGTLCISGGADGMIRLFDM-RSFDCLNGWLAHEGEICSLQ 478 4566777777777777777777777766552134455556666777777777777777777777777777775.56777777777777777777 PP Beta-prop_EML_2 132 wsedskylqsnsgdyellfwdaktg.kqvtsasalkdv 168 +s+d +++ s +d++ + w+++++ k++ + + + v FUN_000614-T1 479 FSADETTVYSMGTDGKFIQWSVHRMgKRIADLEIQEGV 516 77777777777777777777776642555555555555 PP == domain 4 score: 8.6 bits; conditional E-value: 0.0024 Beta-prop_EML_2 88 kfspdgklL.avgshdnkiylYdvskkykkvgklkghssfithlDwsedskylqsn 142 +f +g++L +g++ + ++ ++++++v +l +h+s+++++Dws+ ++ + FUN_000614-T1 543 AFDAEGQYLlTCGTESGAVHKVGKNHGLRQVLSLPEHKSPVVSVDWSSLQSCYTCL 598 57777776515678888887777778899******************977665555 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 6.1e-07 0.00039 6 100 .. 273 373 .. 268 397 .. 0.78 2 ? -0.2 0.0 1 6.5e+02 87 116 .. 392 421 .. 374 431 .. 0.80 3 ! 30.0 0.1 6.3e-10 4e-07 179 264 .. 433 519 .. 426 523 .. 0.92 4 ! 7.5 0.0 0.0047 3 164 201 .. 569 608 .. 561 611 .. 0.86 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 6.1e-07 Beta-prop_WDR3_2nd 6 alssddklllsasse.svkiwnvk..slecirtieseyalclafvpg.drhvlvgtkdGklevldlasaelletieaheg..avwsvaltp 90 +ss+ +++ sa ++ vk+wn + ++c + + l+l + p dr +l+gt +Gk++ +d ++ +++ +++ ++ v s++ +p FUN_000614-T1 273 RFSSNGRMVGSADADgIVKVWNYHpdIHTCASVMLKSPLLSLEWAPKqDRLLLLGTGNGKVKFYDTENKKIICDVSTESQypRVVSLSCSP 363 589999***999766489****862146777777889999*****9538999*********************999887522678888888 PP Beta-prop_WDR3_2nd 91 dekglvtgga 100 + +v ++a FUN_000614-T1 364 TGGAFVCSAA 373 7766665443 PP == domain 2 score: -0.2 bits; conditional E-value: 1 Beta-prop_WDR3_2nd 87 altpdekglvtggaDkkvkfwefelveeee 116 ++++ + + +tgg+ +++w+++l++ e+ FUN_000614-T1 392 EMSSMSSSSITGGSGGVLQCWDMKLMKLER 421 5566677899*************9998654 PP == domain 3 score: 30.0 bits; conditional E-value: 6.3e-10 Beta-prop_WDR3_2nd 179 lsldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkvkyWDadkf.ekiqtleghagevwa 264 + ++++l+++g aD i+++ + Dc +ah+ + s++f +++s+g d+k +W + ++i le ++g vw+ FUN_000614-T1 433 NCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSVHRMgKRIADLEIQEGVVWC 519 566777899**********************************************************998746899******99998 PP == domain 4 score: 7.5 bits; conditional E-value: 0.0047 Beta-prop_WDR3_2nd 164 tlkfflslYGhklPvlsldiss..DsklivtgsaDkniki 201 l+ +lsl hk Pv+s+d ss + ++tgs D +i++ FUN_000614-T1 569 GLRQVLSLPEHKSPVVSVDWSSlqSCYTCLTGSVDGTIQV 608 58999***************9733567899*****99987 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 8.7e-05 0.055 61 147 .. 264 347 .. 257 424 .. 0.75 2 ! 32.5 0.1 1.3e-10 8.4e-08 153 240 .. 426 515 .. 401 531 .. 0.81 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 8.7e-05 Beta-prop_EML 61 efergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknl.lvtcGkkhiaFWtlegkklekkk 147 e++++++ Fs+ +g+++ + d + ++ vW+ + + + + + k ++l++e+ p++++l l+ G+ +++F+ e+kk+ + FUN_000614-T1 264 EHHSAIVHCRFSS--NGRMVGSADA--DGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQDRLlLLGTGNGKVKFYDTENKKIICDV 347 5677788888885..4555555444..4588899999888888888888899999998887775145688889999988888765443 PP == domain 2 score: 32.5 bits; conditional E-value: 1.3e-10 Beta-prop_EML 153 sekpkyvlclafsengd.vitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivawdan.l.eklketelpes 240 + p+ + c a+++ng +i+G ++G i +++ + + + aheg++ sl+++ d+t + + g dgk ++w+ + + ++++++e++e FUN_000614-T1 426 EPLPTCINCTAYNHNGTlCISGGADGMIRLFDMRSFDCLNGWL-AHEGEICSLQFSADETTVYSMGTDGKFIQWSVHrMgKRIADLEIQEG 515 456899***********669************99999999988.******************************97513245566666554 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 2.9e-06 0.0018 91 217 .. 262 347 .. 257 379 .. 0.49 2 ! 22.1 0.1 1.5e-07 9.4e-05 47 168 .. 379 502 .. 367 519 .. 0.61 3 ? 1.0 0.0 0.39 2.5e+02 60 121 .. 543 608 .. 536 612 .. 0.53 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 2.9e-06 WDR55 91 iekahespiysllvidenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfnirkkklevqseeyeeellsla 186 +++ h++ +++ + +++ ++d dG+vk+W + ++ s ++ llsl+ FUN_000614-T1 262 YREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYH------------------------------------------PDIHTCASVMLKSPLLSLE 315 34444444455555555555555555555555555..........................................5555555555555555554 PP WDR55 187 lv.keekkvvvGsseGklylfnwgefgahsdr 217 k+++ ++ G+++Gk+++++ ++ ++d FUN_000614-T1 316 WApKQDRLLLLGTGNGKVKFYDTENKKIICDV 347 43123333344555555555544444333333 PP == domain 2 score: 22.1 bits; conditional E-value: 1.5e-07 WDR55 47 lslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkie.kahespiysllv.idenllatGdddGtvklWDlRkkkavmelkehedyi 140 s++ ++ r+ e s+ ++ ++ + +++ d++ kl+++++ + + i++ ++ + +l+++G dG+++l+D+R+ +++ + he i FUN_000614-T1 379 SSSSSRLSQSRSNEMSSMSSSSITGGSGGVLQCWDMKLMKLERQLRlEPLPTCINCTAYnHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEI 474 444555555566666666666666666666666677766666666413344555555441344566677777777777777777777777777777 PP WDR55 141 sdlvvdeekklLlatsgdGtltvfnirk 168 +l ++ ++ ++ + + dG + +++++ FUN_000614-T1 475 CSLQFSADETTVYSMGTDGKFIQWSVHR 502 7777777777777777777666665544 PP == domain 3 score: 1.0 bits; conditional E-value: 0.39 WDR55 60 eFsedGkklfsvskDk.siavldvetgklkkkiekahespiysllvi...denllatGdddGtvkl 121 +F+++G+ l+++ ++ +++ + ++g h+sp+ s+ + +++ tG dGt+++ FUN_000614-T1 543 AFDAEGQYLLTCGTESgAVHKVGKNHGLRQVLSLPEHKSPVVSVDWSslqSCYTCLTGSVDGTIQV 608 567777777776655312333333333333333456777776664431113445666777776664 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.049 32 74 108 .. 262 296 .. 257 311 .. 0.66 2 ? 5.7 0.0 0.016 10 44 96 .. 316 372 .. 308 389 .. 0.62 3 ! 28.7 0.0 1.5e-09 9.9e-07 18 113 .. 409 506 .. 392 544 .. 0.81 4 ? 0.2 0.0 0.79 5e+02 48 84 .. 549 586 .. 527 604 .. 0.64 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.049 Beta-prop_WDR90_POC16_2nd 74 hkqhrgkvtglvfspdgeylysacslGslalydas 108 +++h+++++ fs++g+++ sa + G++ +++ FUN_000614-T1 262 YREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYH 296 56677777777777777777777777766666544 PP == domain 2 score: 5.7 bits; conditional E-value: 0.016 Beta-prop_WDR90_POC16_2nd 44 fhPskq.vfacGfssGvvrvfsveatsllaehkq..hrgkvtglvfspdg.eylysa 96 + P+++ ++ G +G v++++ e+ +++ + ++ + +v++l sp+g ++++sa FUN_000614-T1 316 WAPKQDrLLLLGTGNGKVKFYDTENKKIICDVSTesQYPRVVSLSCSPTGgAFVCSA 372 444443145567777777777777777776654411445677777777651344444 PP == domain 3 score: 28.7 bits; conditional E-value: 1.5e-09 Beta-prop_WDR90_POC16_2nd 18 iriWdldtlqqlydfsaseeaPcav...afhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgeylysacs 98 ++ Wd++ ++ ++ e P+++ a+ + ++ ++G +G++r f++++ + l h+g++ +l fs d + +ys+++ FUN_000614-T1 409 LQCWDMKLMKLERQLR-LEPLPTCInctAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGT 491 5677777665333333.3444444322278888889999********************************************* PP Beta-prop_WDR90_POC16_2nd 99 lGslalydaseeeye 113 G+ ++++ + + FUN_000614-T1 492 DGKFIQWSVHRMGKR 506 *******99876555 PP == domain 4 score: 0.2 bits; conditional E-value: 0.79 Beta-prop_WDR90_POC16_2nd 48 kqvfacGfssGvvrvfsvea.tsllaehkqhrgkvtgl 84 + +++cG +sG+v+ + ++ + + +h++ v+++ FUN_000614-T1 549 QYLLTCGTESGAVHKVGKNHgLRQVLSLPEHKSPVVSV 586 44678999999997654332134444555555555555 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.25 1.6e+02 36 68 .. 264 296 .. 255 316 .. 0.81 2 ! 18.8 0.0 3.1e-06 0.002 38 82 .. 308 353 .. 291 362 .. 0.80 3 ! 14.7 0.0 6.2e-05 0.039 40 89 .. 431 480 .. 422 482 .. 0.94 4 ? -1.1 0.0 5.1 3.2e+03 52 89 .. 551 589 .. 540 597 .. 0.62 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.25 ANAPC4_WD40 36 kedsevtslaWkpdGklLavaysdgevrlldve 68 ++ s++ + +++ +G++ a +dg v++ + + FUN_000614-T1 264 EHHSAIVHCRFSSNGRMVGSADADGIVKVWNYH 296 678899999******************998765 PP == domain 2 score: 18.8 bits; conditional E-value: 3.1e-06 ANAPC4_WD40 38 dsevtslaWkpd.GklLavaysdgevrlldvesgklvhslsaksdk 82 +s sl+W p+ +lL ++ +g+v+++d e++k++ +s++s+ FUN_000614-T1 308 KSPLLSLEWAPKqDRLLLLGTGNGKVKFYDTENKKIICDVSTESQY 353 666779***996378999**********************999886 PP == domain 3 score: 14.7 bits; conditional E-value: 6.2e-05 ANAPC4_WD40 40 evtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdkitcleWa 89 ++++ a++++G+l + + +dg +rl+d+ s ++++ + a++ +i++l+++ FUN_000614-T1 431 CINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFS 480 68999****************************************99987 PP == domain 4 score: -1.1 bits; conditional E-value: 5.1 ANAPC4_WD40 52 lLavaysdgevrlldvesg.klvhslsaksdkitcleWa 89 lL ++++g v+ + + g + v sl+ +++ +++++W+ FUN_000614-T1 551 LLTCGTESGAVHKVGKNHGlRQVLSLPEHKSPVVSVDWS 589 445677777777766666644455555555557777776 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.2 7.1 4.6e+03 52 65 .. 148 161 .. 115 196 .. 0.50 2 ! 16.2 0.0 9.5e-06 0.006 84 170 .. 260 344 .. 247 361 .. 0.80 3 ! 29.2 1.0 1.1e-09 6.8e-07 105 212 .. 400 510 .. 380 527 .. 0.80 4 ? -2.6 0.0 5.2 3.3e+03 168 183 .. 571 586 .. 543 609 .. 0.50 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 7.1 Beta-prop_TEP1_2nd 52 kllasasedltvrl 65 + l s+s +++l FUN_000614-T1 148 EQLKSSSPGASISL 161 33344444444444 PP == domain 2 score: 16.2 bits; conditional E-value: 9.5e-06 Beta-prop_TEP1_2nd 84 svlrghtgavtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaW..tkddllvscssdGsvglWdiekeqrl 170 r+h++a+ c fs +G+++ ++ d + +W+ + + ++ + + + + W +d ll+ ++++G v ++d e+++ + FUN_000614-T1 260 DSYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHP----DIHTCASVMLKSPLLSLEWapKQDRLLLLGTGNGKVKFYDTENKKII 344 5679******************************7643....3334444444555555555225899***************9998765 PP == domain 3 score: 29.2 bits; conditional E-value: 1.1e-09 Beta-prop_TEP1_2nd 105 latggrdrsllcWdvrvp..kaPvlirsllachrdWvtgcaWtkd.dllvscssdGsvglWdiekeqrlgkflGhqsavsavv..aveehv 190 tgg l cWd++ + + + l++c + + a+ ++ +l +s+ +dG ++l+d+++ + l+ +l h+ ++++ a e v FUN_000614-T1 400 SITGGSGGVLQCWDMKLMklERQLRLEPLPTC----INCTAYNHNgTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQfsADETTV 486 4689999999*****98733455667788888....77888877626779******************************98532667789 PP Beta-prop_TEP1_2nd 191 vsvgrdGllkvWdlq..Gveltsi 212 s+g dG ++ W+ + G ++ + FUN_000614-T1 487 YSMGTDGKFIQWSVHrmGKRIADL 510 9***********854115555555 PP == domain 4 score: -2.6 bits; conditional E-value: 5.2 Beta-prop_TEP1_2nd 168 qrlgkflGhqsavsav 183 +++ + h+s+v +v FUN_000614-T1 571 RQVLSLPEHKSPVVSV 586 2333333333333333 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.0013 0.82 83 151 .. 261 329 .. 238 353 .. 0.85 2 ! 19.4 0.0 9.3e-07 0.00059 90 146 .. 431 487 .. 354 496 .. 0.91 3 ? 3.2 0.0 0.078 50 97 157 .. 545 606 .. 518 612 .. 0.77 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0013 WD40_MABP1-WDR62_2nd 83 seldsknGvRvlkvspdgkhlasGDrsGniriydletleellkieahdsevlcleyskpetglkllasa 151 s ++++ + ++s +g+++ s D G +++++ + +++ + s +l+le++ +++ l ll ++ FUN_000614-T1 261 SYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQDRLLLLGTG 329 4567888899999**********************9988888888999********9999888887664 PP == domain 2 score: 19.4 bits; conditional E-value: 9.3e-07 WD40_MABP1-WDR62_2nd 90 GvRvlkvspdgkhlasGDrsGniriydletleellkieahdsevlcleyskpetglk 146 + + +++g + sG G+ir++d+++++ l ah++e+ +l++s et + FUN_000614-T1 431 CINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVY 487 5778888999****************************************9998765 PP == domain 3 score: 3.2 bits; conditional E-value: 0.078 WD40_MABP1-WDR62_2nd 97 spdgkh.lasGDrsGni.riydletleellkieahdsevlcleyskpetglkllasasRDRli 157 ++g+ l +G sG + ++ + + l+++l++ h s v+++++s+ ++ ++ l+ +s D i FUN_000614-T1 545 DAEGQYlLTCGTESGAVhKVGKNHGLRQVLSLPEHKSPVVSVDWSSLQSCYTCLT-GSVDGTI 606 5566652578889998845777788999999999999999999999998877774.4455555 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.0 0.00016 0.1 236 296 .. 262 323 .. 259 350 .. 0.83 2 ? -1.7 0.0 2.9 1.9e+03 264 293 .. 333 365 .. 324 376 .. 0.53 3 ! 19.6 0.0 9.6e-07 0.00061 165 270 .. 393 501 .. 370 517 .. 0.83 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00016 Beta-prop_WDR36-Utp21_2nd 236 fsghknritDltfspdarWlitasmDstirtwdl.psgkliDvflvesaatslslsptgdfL 296 +++h++ i fs ++r + +a D +++w+ p + ++s+ sl+ +p++d L FUN_000614-T1 262 YREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYhPDIHTCASVMLKSPLLSLEWAPKQDRL 323 678*****************************974678888999999999999999999866 PP == domain 2 score: -1.7 bits; conditional E-value: 2.9 Beta-prop_WDR36-Utp21_2nd 264 irtwdlpsgkliDvflve...saatslslsptg 293 ++ +d + k+i ++e ++sls sptg FUN_000614-T1 333 VKFYDTENKKIICDVSTEsqyPRVVSLSCSPTG 365 455555555554333333111235566666665 PP == domain 3 score: 19.6 bits; conditional E-value: 9.6e-07 Beta-prop_WDR36-Utp21_2nd 165 vdalnqvvitagadkklkfwkfkskklletlkle...asisklvlhressllavalddfsilvvDidtrrvvRkfsghknritD 245 ++++++ it+g+ + l+ w++k kl ++l+le + i+ ++++++ +l d +i+++D+ + + + h+++i+ FUN_000614-T1 393 MSSMSSSSITGGSGGVLQCWDMKLMKLERQLRLEplpTCINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICS 476 56778889**********************9977111455555666666666666799************************** PP Beta-prop_WDR36-Utp21_2nd 246 ltfspdarWlitasmDstirtwdlp 270 l fs+d + + ++D w++ FUN_000614-T1 477 LQFSADETTVYSMGTDGKFIQWSVH 501 **************99999999875 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.2 2.6 1.7e+03 124 165 .. 21 62 .. 6 135 .. 0.58 2 ? 3.4 0.0 0.094 60 209 245 .. 261 296 .. 239 301 .. 0.83 3 ! 15.3 0.0 2.2e-05 0.014 19 71 .. 293 343 .. 286 373 .. 0.81 4 ? -1.8 0.0 3.7 2.4e+03 215 245 .. 430 459 .. 408 465 .. 0.68 5 ? 1.6 0.0 0.32 2.1e+02 212 249 .. 469 505 .. 460 521 .. 0.75 6 ? 6.1 0.0 0.014 9.2 202 242 .. 568 609 .. 542 614 .] 0.78 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.6 Beta-prop_RIG_2nd 124 lvsvrdslLlvgtedGalqllerkkelekayskllkqealls 165 ++++++++L + e G l l + k e+e s + ++ + FUN_000614-T1 21 VLKLKEQVLSLAEEVGNLTLQKSKLEQELGESRTSRSDTVEE 62 567788888888888888888877777766655444444433 PP == domain 2 score: 3.4 bits; conditional E-value: 0.094 Beta-prop_RIG_2nd 209 tasaekasitsvkwsnansnlllsfsidgkvkvWdle 245 +++++ +i ++s++ ++ s ++dg vkvW+ + FUN_000614-T1 261 SYREHHSAIVHCRFSSNG-RMVGSADADGIVKVWNYH 296 567788999999999865.688999**********76 PP == domain 3 score: 15.3 bits; conditional E-value: 2.2e-05 Beta-prop_RIG_2nd 19 ldlsklsakklsieslkvkskvlsLaWspdken.LAfgTaeGrvGildvekmkv 71 ++ ++ + s+++ks lsL W p++ + L gT++G+v d+e++k FUN_000614-T1 293 WN---YHPDIHTCASVMLKSPLLSLEWAPKQDRlLLLGTGNGKVKFYDTENKKI 343 43...466677778899************9999899**************9986 PP == domain 4 score: -1.8 bits; conditional E-value: 3.7 Beta-prop_RIG_2nd 215 asitsvkwsnansnlllsfsidgkvkvWdle 245 i++ ++++ n l +s ++dg +++ d++ FUN_000614-T1 430 TCINCTAYNH-NGTLCISGGADGMIRLFDMR 459 5566666654.45677888888888887765 PP == domain 5 score: 1.6 bits; conditional E-value: 0.32 Beta-prop_RIG_2nd 212 aekasitsvkwsnansnlllsfsidgkvkvWdleepek 249 a++ +i s+++s ++ + s++ dgk+ W+++ k FUN_000614-T1 469 AHEGEICSLQFSA-DETTVYSMGTDGKFIQWSVHRMGK 505 6788899999996.567899*************98765 PP == domain 6 score: 6.1 bits; conditional E-value: 0.014 Beta-prop_RIG_2nd 202 letlkkitasaekasitsvkwsnans.nlllsfsidgkvkvW 242 + + ++k + sv ws+ +s l+ s+dg+++v FUN_000614-T1 568 HGLRQVLSLPEHKSPVVSVDWSSLQScYTCLTGSVDGTIQVT 609 445566677789999999999999962568999999999985 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.0 2.5e-07 0.00016 110 263 .. 266 498 .. 233 501 .. 0.78 2 ? -2.2 0.0 4.8 3.1e+03 199 244 .. 543 588 .. 538 608 .. 0.63 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 2.5e-07 Beta-prop_WDR36-Utp21_1st 110 itallhpsTYlnKilvgskq..GslqlwNirtgkliytfksfksaitaleqspald.vvaiglasGeivlhnikkdetllklkq 190 +a++h n +vgs++ G +++wN + + +ks+ +le +p d ++ +g+ +G++ +++ + ++++++++ FUN_000614-T1 266 HSAIVHCRFSSNGRMVGSADadGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQDrLLLLGTGNGKVKFYDTENKKIICDVST 349 566666666666667777542389******9987666667779**********99945789**********************9 PP Beta-prop_WDR36-Utp21_1st 191 eeg..pvtsisFrtDgepv................................................................. 207 e++ +v s+s g ++ FUN_000614-T1 350 ESQypRVVSLSCSPTGGAFvcsaaaskkssssssrlsqsrsnemssmssssitggsggvlqcwdmklmklerqlrleplptcin 433 966569999999888744445555666677778888888888889999998888888888888888888888888888888888 PP Beta-prop_WDR36-Utp21_1st 208 ..........latgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkew 263 ++g ++G i l+d+ + ++ aHeg++ +l+f +++ + + g+D + +w FUN_000614-T1 434 ctaynhngtlCISGGADGMIRLFDMRSFDCLNGW-LAHEGEICSLQFSADETTVYSMGTDGKFIQW 498 8888888885666778999999999987666555.4899999999999999999999999888888 PP == domain 2 score: -2.2 bits; conditional E-value: 4.8 Beta-prop_WDR36-Utp21_1st 199 sFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtklef 244 +F +g+ +l +g++sG + +++ ++ H+++v+++ + FUN_000614-T1 543 AFDAEGQYLLTCGTESGAVHKVGKNHGLRQVLSLPEHKSPVVSVDW 588 7888889999999999988655555543333333456666666665 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.1 0.0019 1.2 87 115 .. 264 292 .. 259 306 .. 0.89 2 ? -0.3 0.0 1 6.4e+02 212 251 .. 323 362 .. 293 384 .. 0.71 3 ! 16.2 0.0 9.4e-06 0.006 8 121 .. 394 504 .. 389 522 .. 0.73 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0019 WDR90_beta-prop_4th 87 phavaltaiaysadGqtilsgdkdGlvav 115 h+ a++ +s++G+++ s+d dG+v v FUN_000614-T1 264 EHHSAIVHCRFSSNGRMVGSADADGIVKV 292 59999999******************988 PP == domain 2 score: -0.3 bits; conditional E-value: 1 WDR90_beta-prop_4th 212 lvyvGlGvkkevlfyslrkkqvvekipl.pffavslslspk 251 l +G G +v fy ++k+++ ++ + + +sls++ FUN_000614-T1 323 LLLLGTGN-GKVKFYDTENKKIICDVSTeSQYPRVVSLSCS 362 33455553.46999999999999888752567666666664 PP == domain 3 score: 16.2 bits; conditional E-value: 9.4e-06 WDR90_beta-prop_4th 8 spdeshlatcsedGsvrvwslasmelvvqfqv..lnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelklhphavaltai 95 s+ +s t + G ++ w ++ m+l q+++ l +c a++ + ++G +dG +r+f + + + h+ + ++ FUN_000614-T1 394 SSMSSSSITGGSGGVLQCWDMKLMKLERQLRLepLPTCINCTAYNHNG------TLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSL 477 566677788888899999999999888777642255555565555444......446788899999999999999888889999999999 PP WDR90_beta-prop_4th 96 aysadGqtilsgdkdG.lvavssprtG 121 ++sad t+ s + dG ++ s r G FUN_000614-T1 478 QFSADETTVYSMGTDGkFIQWSVHRMG 504 999999999999998833455555555 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 2.8 6.3 4e+03 131 168 .. 101 139 .. 24 203 .. 0.51 2 ? 3.6 0.1 0.066 42 47 81 .. 261 295 .. 259 303 .. 0.80 3 ! 7.7 0.0 0.0037 2.4 149 221 .. 311 386 .. 298 409 .. 0.72 4 ! 15.2 0.1 2e-05 0.013 140 209 .. 423 492 .. 372 508 .. 0.77 5 ! 16.1 0.0 1e-05 0.0064 16 101 .. 435 521 .. 425 612 .. 0.64 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 6.3 EIF3I 131 eeeeeeepvlkieveeskvtvalw.saldktiitghedg 168 ++++ +++ ++ e++++k++ + +++++i he+ FUN_000614-T1 101 KDSKPQQQQMQGENAQAKLKRQQLmRQQQQQIQLLHEQQ 139 222222233333333333333222022233333333322 PP == domain 2 score: 3.6 bits; conditional E-value: 0.066 EIF3I 47 tyeGheGavwsidvdsettllvtgsadntvklWdv 81 +y+ h+ a+ + +s+ +++ ++ ad vk+W+ FUN_000614-T1 261 SYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNY 295 57788888888888888888888888888888875 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0037 EIF3I 149 vtvalws.aldktiitghedgeiskydlktgeklksvkehek..qitdlqlskdktylitaskDktaklldvetle 221 + + w+ ++d+ ++ g+ +g+++ yd+++++++ +v+++++ ++ l +s+ ++ ++ ++ + +++ l+ FUN_000614-T1 311 LLSLEWApKQDRLLLLGTGNGKVKFYDTENKKIICDVSTESQypRVVSLSCSPTGGAFVCSAAASKKSSSSSSRLS 386 5566777246788999****************99887765542379999999999999987665555555555554 PP == domain 4 score: 15.2 bits; conditional E-value: 2e-05 EIF3I 140 lkieveeskvtvalwsaldktiitghedgeiskydlktgeklksvkehekqitdlqlskdktylitaskD 209 l++e + +++++++++++ i+g +dg i +d+++ ++l+ +he +i lq+s+d+t++ + D FUN_000614-T1 423 LRLEPLPTCINCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTD 492 4555555667888999999999999999999999999999999999999999999999999998777666 PP == domain 5 score: 16.1 bits; conditional E-value: 1e-05 EIF3I 16 ikynreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdve.tGkelktletktavrsvef 101 yn++G l +s + d ++ ++ + + l + heG + s++ + + t++ + +d ++ W+v+ Gk ++ le++ v +e FUN_000614-T1 435 TAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSVHrMGKRIADLEIQEGVVWCET 521 457777777777777777777777777777777777777777777777777777777777777777525777777777776666654 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.1 0.0 0.001 0.67 99 131 .. 263 295 .. 257 311 .. 0.86 2 ? 2.0 0.0 0.14 91 62 119 .. 310 370 .. 298 376 .. 0.73 3 ! 6.6 0.1 0.006 3.8 81 137 .. 450 506 .. 399 517 .. 0.85 4 ? 1.9 0.0 0.16 1e+02 74 115 .. 551 593 .. 525 608 .. 0.61 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.001 Beta-prop_IFT140_1st 99 klhkaeitvlewssngsrLvsgdksGvlvvWkl 131 + h+++i+ ++ssng + s+d G++ vW+ FUN_000614-T1 263 REHHSAIVHCRFSSNGRMVGSADADGIVKVWNY 295 568999*************************86 PP == domain 2 score: 2.0 bits; conditional E-value: 0.14 Beta-prop_IFT140_1st 62 qvtvlsWHPtk.kilavgwesGevlvlneqdkelte..lpklhkaeitvlewssngsrLvs 119 +l+W P++ ++l +g +G v + +++k+ + ++++ +++ l+ s +g +v FUN_000614-T1 310 PLLSLEWAPKQdRLLLLGTGNGKVKFYDTENKKIICdvSTESQYPRVVSLSCSPTGGAFVC 370 56789999987357789999****9999999998651133455567777888877777665 PP == domain 3 score: 6.6 bits; conditional E-value: 0.006 Beta-prop_IFT140_1st 81 sGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWkldqrGrl 137 +G + ++ ++ ++ + +h+ ei+ l++s+ +++ s + G ++ W + + G+ FUN_000614-T1 450 DGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSVHRMGKR 506 56677777777777777789******************************9999975 PP == domain 4 score: 1.9 bits; conditional E-value: 0.16 Beta-prop_IFT140_1st 74 ilavgwesGevlvlneqdkelte.lpklhkaeitvlewssngs 115 +l+ g esG v + ++++ + + hk+ ++ ++wss s FUN_000614-T1 551 LLTCGTESGAVHKVGKNHGLRQVlSLPEHKSPVVSVDWSSLQS 593 4566666666665555544333203345777777777776555 PP >> Ge1_WD40 WD40 region of Ge1, enhancer of mRNA-decapping protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.9 0.0 0.00036 0.23 185 215 .. 264 294 .. 256 322 .. 0.92 2 ! 12.6 0.1 0.00011 0.068 188 261 .. 430 501 .. 410 563 .. 0.69 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00036 Ge1_WD40 185 eedsllveaalspdGtalatasadGlvkffq 215 e++s +v++ +s++G ++ a adG+vk + FUN_000614-T1 264 EHHSAIVHCRFSSNGRMVGSADADGIVKVWN 294 799*************************997 PP == domain 2 score: 12.6 bits; conditional E-value: 0.00011 Ge1_WD40 188 sllveaalspdGtalatasadGlvkffqiyledneeqrclheWkPhdGkklssllfldnlkk.q...sevqfWrfvit 261 +++ ++a+ +Gt adG++++f d + cl W h+G ++sl f + ++ +f ++ + FUN_000614-T1 430 TCINCTAYNHNGTLCISGGADGMIRLF-----DMRSFDCLNGWLAHEGE-ICSLQFSADETTvYsmgTDGKFIQWSVH 501 4899*******************9987.....567778**********6.7888776554331212355666666665 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.17 1.1e+02 120 153 .. 262 295 .. 244 311 .. 0.81 2 ! 10.8 0.0 0.00035 0.22 275 345 .. 432 503 .. 425 508 .. 0.88 3 ! 7.0 0.0 0.005 3.2 92 153 .. 547 611 .. 531 614 .] 0.83 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.17 NBCH_WD40 120 irqhkdvvscvavtsdgsvlatGsydttvmvwev 153 r+h+ + +s+g+++ + d v vw+ FUN_000614-T1 262 YREHHSAIVHCRFSSNGRMVGSADADGIVKVWNY 295 5655555555578999999999999999999975 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00035 NBCH_WD40 275 lnclelsscgeflvcaGdqGqivvrslkslevvkryeGiGkaitsltvtpeecfl.aGtkdGsllvysiena 345 +nc + g + +++G +G i +++++s++ ++ + i sl+ +++e + + dG+++ +s+ + FUN_000614-T1 432 INCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVySMGTDGKFIQWSVHRM 503 7999999********************************99******99888655255679*****999875 PP == domain 3 score: 7.0 bits; conditional E-value: 0.005 NBCH_WD40 92 senfliscGnwensfqvislsdG.rlvqsirqhkdvvscvavtsdgsv..latGsydttvmvwev 153 ++l++cG+ + + + + G r v s+ +hk v +v +s s tGs d t+ v ++ FUN_000614-T1 547 EGQYLLTCGTESGAVHKVGKNHGlRQVLSLPEHKSPVVSVDWSSLQSCytCLTGSVDGTIQVTSL 611 468*******9999999998888689*********999999998777522679*******98765 PP >> Beta-prop_IP5PC_F IP5P C-F beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.094 60 105 140 .. 260 296 .. 237 309 .. 0.82 2 ! 15.6 0.1 1.2e-05 0.0078 302 392 .] 400 498 .. 365 498 .. 0.72 3 ? 1.2 0.0 0.3 1.9e+02 95 136 .. 564 608 .. 531 611 .. 0.80 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.094 Beta-prop_IP5PC_F 105 lswqahrgpvlslvissyGdlwsgse.gGvikvwpwe 140 s++ h+++++ ss G + +++ +G++kvw ++ FUN_000614-T1 260 DSYREHHSAIVHCRFSSNGRMVGSADaDGIVKVWNYH 296 57999**************997655427******985 PP == domain 2 score: 15.6 bits; conditional E-value: 1.2e-05 Beta-prop_IP5PC_F 302 iwtGcsnGllvqwdgnGnrlk.dfkhhpcavlcfct....fgsriwvGyvsGviqvldleG.nllagwvahnspvikla..vgagyvfslat 385 tG+s G+l wd + +l+ +++ p ct g+ G + G+i+++d+ + l gw+ah++++ l ++ v+s+ t FUN_000614-T1 400 SITGGSGGVLQCWDMKLMKLErQLRLEPLPTCINCTaynhNGTLCISGGADGMIRLFDMRSfDCLNGWLAHEGEICSLQfsADETTVYSMGT 491 45999**********9999852566665554444542221466677799**********86489**********987751156799*****9 PP Beta-prop_IP5PC_F 386 hGGirGw 392 G w FUN_000614-T1 492 DGKFIQW 498 9976555 PP == domain 3 score: 1.2 bits; conditional E-value: 0.3 Beta-prop_IP5PC_F 95 ssddtsfkeglswqahrgpvlslvissyGdlws...gsegGvikv 136 + ++ +++ ls h++pv+s+ ss ++ gs +G+i+v FUN_000614-T1 564 VGKNHGLRQVLSLPEHKSPVVSVDWSSLQSCYTcltGSVDGTIQV 608 5567789999*************9998877665111566677766 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.2 0.0015 0.99 141 245 .. 264 372 .. 257 417 .. 0.73 2 ! 11.7 0.1 0.00021 0.14 193 240 .. 438 485 .. 412 506 .. 0.79 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0015 WD40_Gbeta 141 ghtgylsccrflddnqivtss.gdttcalwdietgqqttvfvghtgdvmslslapdt.rlfvsgacdasaklwdvreg..lcrqtfighesdinai 232 h + crf + ++v s+ d + +w+ +t++ v ++sl ap + rl++ g+ + +k++d + +c + + + ++ FUN_000614-T1 264 EHHSAIVHCRFSSNGRMVGSAdADGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQdRLLLLGTGNGKVKFYDTENKkiICDVSTESQYPRVVSL 359 566778889****999998863689999**************************975389999**********98765226776666677778888 PP WD40_Gbeta 233 affpngealatgs 245 + p g a++ + FUN_000614-T1 360 SCSPTGGAFVCSA 372 8889998886432 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00021 WD40_Gbeta 193 apdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngea 240 ++ l +sg +d ++l+d+r c + ++ he +i ++ f + ++ FUN_000614-T1 438 NHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETT 485 456678889999999999999999999999999999988888766544 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 8.7 5.5e+03 82 129 .. 172 220 .. 169 224 .. 0.56 2 ! 11.3 0.0 0.00027 0.17 67 103 .. 263 299 .. 241 310 .. 0.86 3 ? -0.6 0.0 1.1 7.1e+02 327 368 .. 330 372 .. 320 375 .. 0.81 4 ? 5.5 0.0 0.016 10 128 166 .. 469 508 .. 387 523 .. 0.89 5 ? -2.8 0.0 5.2 3.3e+03 129 153 .. 579 605 .. 567 610 .. 0.55 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 8.7 Beta-prop_CAF1B_HIR1 82 gelLasgdDesviiiWklkeeee.einlleeeeeenketwlvlkvlrGh 129 + +La++d++ k + +++ + + ++++ee+++ k+l G FUN_000614-T1 172 QAILAATDEDVSAKCAKSTVTKSqSFDRANNKHEEDENLLHRSKTLPGR 220 6678888888777777766655413333334444444445556777665 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00027 Beta-prop_CAF1B_HIR1 67 trhqkavnvvrfspsgelLasgdDesviiiWklkeee 103 + h+ a+ +rfs++g+++ s+d ++++ +W+ + + FUN_000614-T1 263 REHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDI 299 569999999**********************987765 PP == domain 3 score: -0.6 bits; conditional E-value: 1.1 Beta-prop_CAF1B_HIR1 327 kksvllYDtqqkvPfalis.nihytrltDlaWssdgkllvvss 368 + +v +YDt +k + +s + y r+ l+ s g +v s+ FUN_000614-T1 330 NGKVKFYDTENKKIICDVStESQYPRVVSLSCSPTGGAFVCSA 372 567999***9999998887357999*****9999999999886 PP == domain 4 score: 5.5 bits; conditional E-value: 0.016 Beta-prop_CAF1B_HIR1 128 GhledvyDlswspdskklisgsvDntailWdvek.gkkla 166 h +++ l +s+d++++ s D + i W v++ gk++a FUN_000614-T1 469 AHEGEICSLQFSADETTVYSMGTDGKFIQWSVHRmGKRIA 508 48899***************************98345554 PP == domain 5 score: -2.8 bits; conditional E-value: 5.2 Beta-prop_CAF1B_HIR1 129 hledvyDlswspdsk..klisgsvDnt 153 h+ v + ws+ ++ + ++gsvD t FUN_000614-T1 579 HKSPVVSVDWSSLQScyTCLTGSVDGT 605 555555555554332113455555554 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 2.1 0.029 19 206 280 .. 60 135 .. 30 180 .. 0.79 2 ! 15.2 0.0 2.3e-05 0.015 61 159 .. 265 362 .. 245 377 .. 0.85 3 ? 2.1 0.1 0.22 1.4e+02 112 140 .. 436 464 .. 427 518 .. 0.75 4 ? -2.0 0.0 3.9 2.5e+03 144 157 .. 574 587 .. 542 612 .. 0.54 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.029 WD40_RFWD3 206 lsfeeksrhvLvssRpskrqpkvrhvvceleasedkteeeviscnv.vqtfqagnsqklLsrsalfkspekddkll 280 ++ +++++ +++ss s++ + + + ++ ++++++++++ ++++ q++q+ n q L r++l+++++++ +ll FUN_000614-T1 60 VEEDDTDEFCVISSSKSQKFLPTMKRLSNIFKDKQDKNKKSKDSKPqQQQMQGENAQAKLKRQQLMRQQQQQIQLL 135 5566677779999999988877777777776666666666666666156899999***********9988776654 PP == domain 2 score: 15.2 bits; conditional E-value: 2.3e-05 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsnt.vvqtYetdspvWsCcWseddsnylyaGlqnGsvlvfDiRqtssevselekeesrspvvs 155 H+ ai F+s+ +++ sa D +k+ + + + + + ++sp+ s W+ ++ +l+ G+ nG+v +D+ + ++ + +++e++ vvs FUN_000614-T1 265 HHSAIVHCRFSSN-GRMVGSADADGIVKVWNYHPDIhTCASVMLKSPLLSLEWAPKQDRLLLLGTGNGKVKFYDTEN-KKIICDVSTESQYPRVVS 358 7777888889887.8999***************99626678899******************************976.567788889999999999 PP WD40_RFWD3 156 Layv 159 L+ FUN_000614-T1 359 LSCS 362 9865 PP == domain 3 score: 2.1 bits; conditional E-value: 0.22 WD40_RFWD3 112 WseddsnylyaGlqnGsvlvfDiRqtsse 140 +++ ++ +G ++G + +fD+R+ + FUN_000614-T1 436 AYNHNGTLCISGGADGMIRLFDMRSFDCL 464 44556666777888999999999987654 PP == domain 4 score: -2.0 bits; conditional E-value: 3.9 WD40_RFWD3 144 lekeesrspvvsLa 157 l+ +e++spvvs+ FUN_000614-T1 574 LSLPEHKSPVVSVD 587 44455555665543 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.044 28 46 88 .. 276 319 .. 259 344 .. 0.70 2 ! 11.6 0.0 0.00028 0.18 187 260 .. 430 503 .. 411 515 .. 0.78 3 ? 0.1 0.0 0.86 5.5e+02 233 255 .. 541 563 .. 517 608 .. 0.74 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.044 Beta-prop_WDR75_1st 46 snhlqvyscsldgtvrlwdftdgilik.tfvvgykilslyvsak 88 sn v s+ +dg v++w++ i+ +++++ ++lsl + k FUN_000614-T1 276 SNGRMVGSADADGIVKVWNYHPDIHTCaSVMLKSPLLSLEWAPK 319 45556778888888888888888775414556677777765555 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00028 Beta-prop_WDR75_1st 187 tcvac....hpkddciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnllsGGvesvlvqwryeee 260 tc+ c h ci+ G dG irl+ + + h+ + sl+f+++ t ++s G + ++qw ++ FUN_000614-T1 430 TCINCtaynHNGTLCIS-GGADGMIRLF---DMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSVHRM 503 56666332344555876.5589***995...4444455666778999**************************98765 PP == domain 3 score: 0.1 bits; conditional E-value: 0.86 Beta-prop_WDR75_1st 233 slvftpeGtnllsGGvesvlvqw 255 ++f +eG ll+ G es v+ FUN_000614-T1 541 MFAFDAEGQYLLTCGTESGAVHK 563 56788999999999999877754 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.0 6.9e-05 0.044 58 116 .. 285 344 .. 264 357 .. 0.66 2 ? -1.2 0.0 1.8 1.1e+03 86 135 .. 434 483 .. 406 513 .. 0.58 3 ? 0.5 0.0 0.55 3.5e+02 271 313 .. 548 590 .. 536 610 .. 0.69 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 6.9e-05 Beta-prop_WDR19_1st 58 eksslvllwdantkktskldtglkdkltfllWskks.piLavGtskGnlllYnkktskki 116 + +v +w+ + + + lk++l l W+ k+ +L +Gt +G++ +Y+ +++k i FUN_000614-T1 285 DADGIVKVWNYHPDIHTCASVMLKSPLLSLEWAPKQdRLLLLGTGNGKVKFYDTENKKII 344 345667777777777777777777777777777544145667777777777777776654 PP == domain 2 score: -1.2 bits; conditional E-value: 1.8 Beta-prop_WDR19_1st 86 fllWskkspiLavGtskGnlllYnkktskkipilGkHskkItcgawsken 135 + + +++++ + G + G + l++ ++ + H+ +I++ ++s+++ FUN_000614-T1 434 CTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADE 483 33344444444444444444444444444444444444444444444443 PP == domain 3 score: 0.5 bits; conditional E-value: 0.55 Beta-prop_WDR19_1st 271 lkkvascgdntvkihelsdlkevkeiieldeeekelekvewse 313 + +++cg ++ +h++ + + ++++++l e+++ + +v+ws+ FUN_000614-T1 548 GQYLLTCGTESGAVHKVGKNHGLRQVLSLPEHKSPVVSVDWSS 590 4556677777777777777777777777777777777777764 PP >> PROPPIN PROPPIN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 9.1e-05 0.058 112 198 .. 412 498 .. 401 515 .. 0.78 2 ? 0.9 0.0 0.45 2.9e+02 87 135 .. 540 588 .. 525 608 .. 0.73 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 9.1e-05 PROPPIN 112 kdmkllktlldi..panptglcalsinhsnsylaypgsltsgeivlydgnslktvctiaahegtlaaitfnasgsklasasekgtvirv 198 dmkl+k ++ pt + + + nh l+ g + g i l+d s+ + aheg ++++ f a + + s g i+ FUN_000614-T1 412 WDMKLMKLERQLrlEPLPTCINCTAYNHN-GTLCISGG-ADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQW 498 58888886555500555666667778885.55666665.68**********************************99999999988864 PP == domain 2 score: 0.9 bits; conditional E-value: 0.45 PROPPIN 87 nilsirlnrqrllvcleesiyihnikdmkllktlldipanptglcalsi 135 ++++ + q ll c es +h++ + l+ +l +p + ++++ FUN_000614-T1 540 KMFAFDAEGQYLLTCGTESGAVHKVGKNHGLRQVLSLPEHKSPVVSVDW 588 4667777889***************************998777665544 PP >> WD_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, WD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 6.7 4.3e+03 299 325 .. 313 340 .. 308 363 .. 0.74 2 ? -0.7 0.1 1.1 7.3e+02 195 221 .. 396 422 .. 367 426 .. 0.71 3 ! 11.3 0.0 0.00027 0.17 105 163 .. 443 500 .. 430 514 .. 0.88 4 ? 1.2 0.0 0.32 2e+02 288 335 .. 531 578 .. 527 602 .. 0.81 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 6.7 WD_LRWD1 299 slstcpdk.nlvlcgdeegsvwiydveh 325 sl +p + l+l g +g v yd e FUN_000614-T1 313 SLEWAPKQdRLLLLGTGNGKVKFYDTEN 340 5555554415788999999999999886 PP == domain 2 score: -0.7 bits; conditional E-value: 1.1 WD_LRWD1 195 cpdsfllagceggcgcwdvrldqpqkq 221 s + g g cwd++l + ++q FUN_000614-T1 396 MSSSSITGGSGGVLQCWDMKLMKLERQ 422 445556666666779****99887766 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00027 WD_LRWD1 105 mlaaaglrgmvrllhvragfccsvirahkkaiatlcfspthethlftasydkriilwdi 163 + + g gm+rl+ +r+ c + ah+ i++l fs et +++ d + i w + FUN_000614-T1 443 LCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSA-DETTVYSMGTDGKFIQWSV 500 45567899*****************************96.7999*************87 PP == domain 4 score: 1.2 bits; conditional E-value: 0.32 WD_LRWD1 288 lqwsptslayfslstcpdknlvlcgdeegsvwiydvehllkqppplet 335 ++sp+s + + + l+ cg e g+v +h l+q l FUN_000614-T1 531 YKYSPSSYGKMFAFDAEGQYLLTCGTESGAVHKVGKNHGLRQVLSLPE 578 578899988777777888999*************99**9999877654 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.4 9.2 5.9e+03 277 305 .. 117 145 .. 84 152 .. 0.56 2 ? 5.4 0.0 0.02 13 62 140 .. 269 342 .. 256 419 .. 0.66 3 ? 5.4 0.0 0.02 13 21 88 .. 433 500 .. 425 514 .. 0.83 4 ? 3.7 0.0 0.068 43 24 88 .. 543 611 .. 533 613 .. 0.75 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 9.2 Beta-prop_HPS5 277 lllseelvltltdsalyildvqsvqvilw 305 l++++++ ++++ +l+ q+ q+ l FUN_000614-T1 117 AKLKRQQLMRQQQQQIQLLHEQQKQLSLL 145 34566666666666666666666666444 PP == domain 2 score: 5.4 bits; conditional E-value: 0.02 Beta-prop_HPS5 62 istvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrv.yiGdekGkvsvtklsssk 140 i + +s++ +v a +g v v++ p + s +s + +L W ++ r+ G +Gkv+ + +++k FUN_000614-T1 269 IVHCRFSSNGRMVGSADADGIVKVWNYH------PDIHTCASVMLKSPLLSLEWAPKQDRLlLLGTGNGKVKFYDTENKK 342 5556666666666666666666666664......4444444445555666666666665541456666666666666655 PP == domain 3 score: 5.4 bits; conditional E-value: 0.02 Beta-prop_HPS5 21 kytclavsrkflaLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvel 88 ++t+ + + G G + +f+ + +l+ a+eg+i+ + +s+de +v +++g+ + +++ FUN_000614-T1 433 NCTAYNHNGTLCISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSV 500 555555556666779999*******************************9999988888888877766 PP == domain 4 score: 3.7 bits; conditional E-value: 0.068 Beta-prop_HPS5 24 clavsrkf.laLGsstGgvyifsre.alkllqlltakegaistvaisp.dedlvava.tsrglvvvvel 88 +++ ++ l+ G+ +G+v+ + ++ +l+++ l+++++++ v s+ + + +++ + +g + v +l FUN_000614-T1 543 AFDAEGQYlLTCGTESGAVHKVGKNhGLRQVLSLPEHKSPVVSVDWSSlQSCYTCLTgSVDGTIQVTSL 611 5665555515689******98877526899999999999999999999877777775155888888765 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.036 23 65 102 .. 260 297 .. 239 301 .. 0.85 2 ! 15.8 0.0 1.3e-05 0.0083 114 190 .. 265 343 .. 263 362 .. 0.77 3 ? -0.8 0.1 1.4 9e+02 117 117 .. 473 473 .. 426 589 .. 0.61 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.036 Beta-prop_WDR35_TULP_N 65 qtlegHsgavqvvaWNekykkLtssDenGliivWmlyk 102 ++ H++a+ +++ ++ + + s+D +G++ vW ++ FUN_000614-T1 260 DSYREHHSAIVHCRFSSNGRMVGSADADGIVKVWNYHP 297 4567899999999*********************9886 PP == domain 2 score: 15.8 bits; conditional E-value: 1.3e-05 Beta-prop_WDR35_TULP_N 114 nksvvkdlkWssdgqkicivyedGavivGsvdGn..rlwgkelkklklakvewspdg.klllfglkegevhvydsegnfl 190 ++s++++ + ss+g+++ + +dG v v + + + lk + l ++ew+p++ +lll+g+ +g+v++yd+e +++ FUN_000614-T1 265 HHSAIVHCRFSSNGRMVGSADADGIVKVWNYHPDihTCASVMLK-SPLLSLEWAPKQdRLLLLGTGNGKVKFYDTENKKI 343 57889999999999999999999999998765441055555566.69********7527899************876543 PP == domain 3 score: -0.8 bits; conditional E-value: 1.4 Beta-prop_WDR35_TULP_N 117 v 117 FUN_000614-T1 473 E 473 2 PP >> eIF2A Eukaryotic translation initiation factor eIF2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 0.0 0.0039 2.5 101 159 .. 309 369 .. 280 381 .. 0.66 2 ? 0.8 0.0 0.89 5.7e+02 103 145 .. 432 471 .. 412 499 .. 0.73 3 ? -1.0 0.0 3.1 2e+03 148 163 .. 541 556 .. 529 566 .. 0.81 4 ? 0.9 0.0 0.83 5.3e+02 41 86 .. 561 607 .. 555 611 .. 0.77 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0039 eIF2A 101 qkrNtiffspkgklvllaGfgnlaGeieiwdvkkkkkiakaeaa....natlvewspdgryvl 159 ++ ++ + pk+ +ll G gn G+++++d+++kk i + ++ +++ sp+g ++ FUN_000614-T1 309 SPLLSLEWAPKQDRLLLLGTGN--GKVKFYDTENKKIICDVSTEsqypRVVSLSCSPTGGAFV 369 4555678888888888877776..899999999888886554331111445555666655555 PP == domain 2 score: 0.8 bits; conditional E-value: 0.89 eIF2A 103 rNtiffspkgklvllaGfgnlaGeieiwdvkkkkkiakaeaan 145 N+ ++ +g+l + +G G i ++d+ ++++++ a + FUN_000614-T1 432 INCTAYNHNGTLCISGGAD---GMIRLFDMRSFDCLNGWLAHE 471 5899999999999998865...569999999888877654444 PP == domain 3 score: -1.0 bits; conditional E-value: 3.1 eIF2A 148 lvewspdgryvlTatt 163 +++++ +g+y+lT+ t FUN_000614-T1 541 MFAFDAEGQYLLTCGT 556 6789999999999987 PP == domain 4 score: 0.9 bits; conditional E-value: 0.83 eIF2A 41 lyliklkkkksevvelkk.egpihdvaWspnskefavvyGkmpakvs 86 ++ + +++ +v++l + + p+ v Ws+ ++ ++ + G ++ +++ FUN_000614-T1 561 VHKVGKNHGLRQVLSLPEhKSPVVSVDWSSLQSCYTCLTGSVDGTIQ 607 5666666667777777541678****************999987775 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00032 0.21 13 70 .. 279 335 .. 265 338 .. 0.78 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00032 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdre.tkkqvGlFvCeapvlvlevnpnpeseleLvcgDklGkvYf 70 ++ sA D vK+W+ + + + + + ++p+l+le p++ ++ L+ g Gkv f FUN_000614-T1 279 RMVGSADADGIVKVWNYHpDIHTCASVMLKSPLLSLEWAPKQ--DRLLLLGTGNGKVKF 335 5677999********976378899999**********97655..567888888888876 PP >> Cytochrom_D1 Cytochrome D1 heme domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.0 0.00058 0.37 42 149 .. 273 376 .. 258 382 .. 0.87 2 ? -0.2 0.0 0.63 4.1e+02 14 64 .. 450 500 .. 444 538 .. 0.76 3 ? -2.8 0.0 3.8 2.4e+03 175 208 .. 541 574 .. 526 577 .. 0.82 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00058 Cytochrom_D1 42 vfssdgRyvyvigRDgkvtliDLwakk.ivaevkaGlnarsvavS.qddryvivgnYlPgqlvildaetLelvkvisargltvderesRVaavvaa 135 fss+gR v + Dg v++ + + a v + + s++ ++dr+++ g+ g+++ d+e+ + + ++s+ + +RV+++ + FUN_000614-T1 273 RFSSNGRMVGSADADGIVKVWNYHPDIhTCASVMLKSPLLSLEWApKQDRLLLLGTG-NGKVKFYDTENKKIICDVSTES-----QYPRVVSLSCS 362 47888***************999988779**************9999********96.59***********999999865.....458******** PP Cytochrom_D1 136 perrefvvnlkdtg 149 p+ fv + ++ FUN_000614-T1 363 PTGGAFVCSAAASK 376 *******9987665 PP == domain 2 score: -0.2 bits; conditional E-value: 0.63 Cytochrom_D1 14 agkvalldgdskeilarvetgyalHisrvfssdgRyvyvigRDgkvtliDL 64 +g ++l d s++ l+ ++ s fs d+ vy +g Dgk + FUN_000614-T1 450 DGMIRLFDMRSFDCLNGWLAHEGEICSLQFSADETTVYSMGTDGKFIQWSV 500 66677777777777666555555557999***************9765555 PP == domain 3 score: -2.8 bits; conditional E-value: 3.8 Cytochrom_D1 175 DggldpdkRYflaaanaedkvavvdtkegkevil 208 +++d+++ Y+l+ + v v +++g +++l FUN_000614-T1 541 MFAFDAEGQYLLTCGTESGAVHKVGKNHGLRQVL 574 578999999*999988888998888888877765 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.6 3.9e+02 228 258 .. 265 295 .. 259 307 .. 0.90 2 ? -3.0 0.0 5.6 3.5e+03 239 266 .. 319 346 .. 308 353 .. 0.84 3 ? 9.7 0.0 0.00077 0.49 245 303 .. 445 501 .. 429 507 .. 0.83 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.6 Beta-prop_DCAF4 228 hdsavtsvqllqeeqlllaadmaGkiklwdl 258 h+sa+ + + +++ +ad G +k+w+ FUN_000614-T1 265 HHSAIVHCRFSSNGRMVGSADADGIVKVWNY 295 89***************************75 PP == domain 2 score: -3.0 bits; conditional E-value: 5.6 Beta-prop_DCAF4 239 qeeqlllaadmaGkiklwdlratkcvkq 266 ++++lll Gk+k++d ++k + + FUN_000614-T1 319 KQDRLLLLGTGNGKVKFYDTENKKIICD 346 567888888999*******999998865 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00077 Beta-prop_DCAF4 245 laadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslk 303 ++ G i+l+d+r+ c++ + h+ e + l + +e + ++G d ws++ FUN_000614-T1 445 ISGGADGMIRLFDMRSFDCLNGWLAHEGEICSLQ--FSADETTVYSMGTDGKFIQWSVH 501 5556789*******************99988765..56788899999*99999999987 PP >> Caudo_TAP Caudovirales tail fibre assembly protein, lambda gpK # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 5.6 0.0006 0.38 43 91 .. 92 140 .. 37 152 .. 0.76 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0006 Caudo_TAP 43 dkwdgeglkkwvtdkpatkeeliqqAeqekqqllaqAsekiaplqdavd 91 dk+d+++ +k+ + ++++ + +qA+ ++qql++q +++i++l ++ + FUN_000614-T1 92 DKQDKNKKSKDSKPQQQQMQGENAQAKLKRQQLMRQQQQQIQLLHEQQK 140 456666656666666666667789999*****************97765 PP >> eIF-3_zeta Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 13.8 0.0043 2.8 59 215 .. 45 207 .. 26 232 .. 0.58 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0043 eIF-3_zeta 59 kqkaygagsasafaykheedessFslVdnkkskkkkkaakk...kqrqrk.vrgrgeekqrkerkkqqalqkkqgeeekeerakrkk.kk....kg 145 ++ g++ +s ++ +e+d ++F ++ ++ks+k ++k+ k +++++++++ ++ ++qq++ ++ + + k+++ r++ ++ ++ FUN_000614-T1 45 LEQELGESRTSRSDTVEEDDTDEFCVISSSKSQKFLPTMKRlsnI---FKdKQDKNKKSKDSKPQQQQMQGENAQAKLKRQQLMRQQqQQiqllHE 137 45568887778899999*************999933333443221...212222222222222222222222222222222222221111112333 PP eIF-3_zeta 146 rrkgwkdkkdkeqrkreasvevkpdWevleeidfsrLskls.levkepedlesyGsleyYdksydritvkn 215 ++k+ + ++++ ++ + +++ d +l+e d++++ + +v+ +++ + + +d++ ++ + ++ FUN_000614-T1 138 QQKQLSLLEEEQLKSSSPGASISLDKPQLQESDMQAILAATdEDVSAKCAKSTVTKSQSFDRANNKHE-ED 207 33333333677777888888888888999999998877666577877777777777777777776654.34 PP >> WD40_2 WD40 repeated domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 10.7 0.026 17 339 436 .. 92 187 .. 75 200 .. 0.65 2 ? 1.1 0.0 0.27 1.8e+02 134 181 .. 308 363 .. 277 402 .. 0.75 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.026 WD40_2 339 lkkdkekeeeseasgeeeksdeeskeeleseeassskeekkkgvlLqyrlrstsqlpgkllsssgslasdsseslehseedgsiyelledpdvwvr 434 k+dk+k+++++++++++ + e+++++l++ ++ +++++++ lL+++ ++ s l+++ l ss+ as s ++ +e d + + ++d dv+ + FUN_000614-T1 92 DKQDKNKKSKDSKPQQQQMQGENAQAKLKR--QQLMRQQQQQIQLLHEQQKQLSLLEEEQLKSSSPGASISLDKPQLQESDMQAILAATDEDVSAK 185 356666666655555555544444444444..4556666666778888888888888888877777777788889999999888888888888764 PP WD40_2 435 sr 436 FUN_000614-T1 186 CA 187 33 PP == domain 2 score: 1.1 bits; conditional E-value: 0.27 WD40_2 134 kspVlsLk...hsssvLfaGLvnGtvavYarae.gglWd....eesekvvklGvlp 181 ksp lsL+ ++ + L G nG+v Y ++ + d ++ ++vv+l + p FUN_000614-T1 308 KSPLLSLEwapKQDRLLLLGTGNGKVKFYDTENkKIICDvsteSQYPRVVSLSCSP 363 56777777222345789999999999999988844555532113335666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (614 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3202 (0.125347); expected 510.9 (0.02) Passed bias filter: 817 (0.0319828); expected 510.9 (0.02) Passed Vit filter: 116 (0.00454101); expected 25.5 (0.001) Passed Fwd filter: 47 (0.00183989); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 40 [number of targets reported over threshold] # CPU time: 0.56u 0.39s 00:00:00.95 Elapsed: 00:00:00.47 # Mc/sec: 5305.11 // Query: FUN_000615-T1 [L=175] Description: FUN_000615 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-20 72.4 9.6 8.4e-20 72.0 9.6 1.2 1 CTLH_Armc9 Armc9, CTLH-like domain 9.7e-06 26.1 0.9 1.4e-05 25.6 0.0 1.6 2 ARMC9_LisH ARMC9, LIS1 homology motif ------ inclusion threshold ------ 0.013 16.5 0.0 0.023 15.7 0.0 1.4 1 Dimer_MINDY4_N MINDY4, N-terminal dimerisation domain 0.099 13.5 0.1 0.21 12.4 0.1 1.5 1 DHH_CID DHH-CID domain 0.45 11.5 4.2 0.43 11.5 1.7 2.1 2 DUF3417 Protein of unknown function (DUF3417) Domain annotation for each model (and alignments): >> CTLH_Armc9 Armc9, CTLH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.0 9.6 1.6e-23 8.4e-20 4 134 .. 47 168 .. 44 169 .. 0.92 Alignments for each domain: == domain 1 score: 72.0 bits; conditional E-value: 1.6e-23 CTLH_Armc9 4 iq.eellssfddgdlkeffelweellpsslrdt.detakkLefyLhiyfaiyplkksegkkdkkeleesmeefkeyLetkgaelsqttellpfYAL 97 +q ++ + s+d l++f+++++++++++l + ++kkLe+ L + ++i++l++s++ +++ e++e+ ael+++te+++++A+ FUN_000615-T1 47 DQlHQYILSYDIVGLRDFWDYLNDRFFKRLDYQhYTNVKKLEMCLLRLYIIHALQNSKN-----------DKVVEFFEKYTAELQTQTEWREWFAI 131 56689999*********************99875788******************9665...........4699********************** PP CTLH_Armc9 98 PfvpnpeehpsfkelFqdsWvdelrkklekflssllk 134 Pf++npe++ +f ++Fq+ W d++ +l +fl +l++ FUN_000615-T1 132 PFIKNPEQNAAFDMYFQRAWQDTFFLSLYNFLITLFH 168 *******************************988875 PP >> ARMC9_LisH ARMC9, LIS1 homology motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.0 2.8e-09 1.4e-05 6 29 .. 10 33 .. 8 34 .. 0.92 2 ? -3.4 0.2 3.3 1.7e+04 21 26 .. 109 114 .. 106 114 .. 0.74 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 2.8e-09 ARMC9_LisH 6 gmvkEYLkFaeFeeTvksFekECK 29 +++kEYL F +F T+ksFe ++K FUN_000615-T1 10 DVIKEYLIFRGFSGTLKSFESDLK 33 79******************9998 PP == domain 2 score: -3.4 bits; conditional E-value: 3.3 ARMC9_LisH 21 vksFek 26 v+ Fek FUN_000615-T1 109 VEFFEK 114 788998 PP >> Dimer_MINDY4_N MINDY4, N-terminal dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 4.6e-06 0.023 8 47 .. 11 50 .. 6 53 .. 0.86 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 4.6e-06 Dimer_MINDY4_N 8 LVREyLsrkglkkTlktldeElprtessisnrseLikvlh 47 +++EyL+ +g++ Tlk+++ l+ ++++ + +++++lh FUN_000615-T1 11 VIKEYLIFRGFSGTLKSFESDLKADKDKSFRVDKIVDQLH 50 79********************999987777777777776 PP >> DHH_CID DHH-CID domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 4.2e-05 0.21 27 54 .. 104 131 .. 96 154 .. 0.79 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.2e-05 DHH_CID 27 dekgaiefLeeldlelkkdeeWrrWvdl 54 ++++++ef+e+ el+++ eWr+W + FUN_000615-T1 104 KNDKVVEFFEKYTAELQTQTEWREWFAI 131 56789********************864 PP >> DUF3417 Protein of unknown function (DUF3417) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.42 2.1e+03 57 78 .. 32 53 .. 25 60 .. 0.81 2 ? 11.5 1.7 8.4e-05 0.43 18 94 .. 64 139 .. 53 150 .. 0.84 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.42 DUF3417 57 laedeeflarleevlaeleeyl 78 l++d++ r+++++++l++y+ FUN_000615-T1 32 LKADKDKSFRVDKIVDQLHQYI 53 6777888889999999999997 PP == domain 2 score: 11.5 bits; conditional E-value: 8.4e-05 DUF3417 18 sWneeareLFkeldpelweevkhnPvklLeevsqerleelaedeeflarleevlaeleeyleektwfqkkaeeekke 94 W+ +++Fk+ld +++++vk+ + lL+ + l++ ++d + ++ +e+ +ael++++e ++wf+ ++ ++ FUN_000615-T1 64 FWDYLNDRFFKRLDYQHYTNVKKLEMCLLRLYIIHALQNSKND-KVVEFFEKYTAELQTQTEWREWFAIPFIKNPEQ 139 5999999**********************99999999987766.689999999********9999*98777333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (175 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1060 (0.0414954); expected 510.9 (0.02) Passed bias filter: 545 (0.0213349); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1799.55 // Query: FUN_000616-T1 [L=167] Description: FUN_000616 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-17 64.5 0.0 2.2e-17 64.2 0.0 1.2 1 PBP Phosphatidylethanolamine-binding protein Domain annotation for each model (and alignments): >> PBP Phosphatidylethanolamine-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.2 0.0 8.6e-22 2.2e-17 16 135 .] 45 160 .. 25 160 .. 0.66 Alignments for each domain: == domain 1 score: 64.2 bits; conditional E-value: 8.6e-22 PBP 16 plawsgvpagtksfalvviDpDapkvse..tg.flHwvvtnipasvtelpegasskvqgkndfgsagYgGpcPpkgdgkHrYvflly....aldve 104 +++w ++ + ++l+++DpDap+ ++ + + Hw+v+nip g ++++ + +Y+G +Ppkg++ HrYvfl y FUN_000616-T1 45 SISWPT--EDGSLYTLLMTDPDAPSREKpkFReWHHWLVVNIP--------GC----DVNKGEVQLKYVGSGPPKGTKLHRYVFLAYkqpsR---- 122 466666..8899***********9888864338**********........22....222222357***********99********54441.... PP PBP 105 a.......ldlkagatkaelgea.ia.ghvlaeaelagnY 135 k+g+++a +++ +a +l++ ++agnY FUN_000616-T1 123 IsysdtvvC-TKPGFERASRKARdLAaTYNLGN-PVAGNY 160 133333221.34555544444444444555555.566665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 450 (0.017616); expected 510.9 (0.02) Passed bias filter: 433 (0.0169505); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1646.85 // Query: FUN_000617-T1 [L=538] Description: FUN_000617 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-27 94.9 0.0 8.2e-27 94.1 0.0 1.4 1 TFR_dimer Transferrin receptor-like dimerisation domain 2e-20 73.8 0.0 4.8e-20 72.6 0.0 1.6 1 Peptidase_M28 Peptidase family M28 2.2e-05 25.0 0.0 5.6e-05 23.7 0.0 1.7 1 PA PA domain ------ inclusion threshold ------ 0.09 13.6 0.0 0.35 11.7 0.0 1.9 2 DDE_Tnp_IS1 IS1 transposase 0.23 12.0 0.0 0.41 11.3 0.0 1.3 1 Mating_N Mating-type protein beta 1 Domain annotation for each model (and alignments): >> TFR_dimer Transferrin receptor-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 94.1 0.0 1.6e-30 8.2e-27 2 120 .. 418 533 .. 417 534 .. 0.95 Alignments for each domain: == domain 1 score: 94.1 bits; conditional E-value: 1.6e-30 TFR_dimer 2 sleplkkaiekfkkaaeefdkwakkweevveasgkessllavrevNdklmlferafldpeglpgrpwfkHvvfapglwtgyagatFPgirdaiea. 96 +l++l + +e+f+k++++f+k+++ + + ++ +vr++Nd++m +eraf+ p+glpgr + v+fap+ ++ y++atFPgi+da+++ FUN_000617-T1 418 TLKHLAREVETFSKNVDAFEKRKAMGT-------DLNNFAQVRMLNDQMMSLERAFIWPNGLPGRVLTRQVLFAPQMHNVYGSATFPGITDALFDi 506 789999999999999999999999977.......89******************************************99**************** PP TFR_dimer 97 ...gdweeaqkqisivakaiekaaesL 120 +dw+e++ q+si+ +++++a++L FUN_000617-T1 507 ektNDWKEVKLQVSIAITCVREVAKLL 533 ************************988 PP >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.6 0.0 9.4e-24 4.8e-20 1 174 [. 151 352 .. 151 363 .. 0.85 Alignments for each domain: == domain 1 score: 72.6 bits; conditional E-value: 9.4e-24 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaa....skqqpkrsvrflffdaEEagllGSkafak..skpelkkirav 89 Nvi+++ g++e d+ +l++ H D + G D sg+a+++e++r l + ++p+rs++f ++aEE gl GS +++ ++ +++ ++ FUN_000617-T1 151 NVIGTIIGSEEpDRMVLVGNHRDAWV--FGGVDPSSGTAVMMEMSRGLGElltkTDWRPRRSIVFCSWGAEEYGLIGSYEWVEenRNMLRERAIMY 244 9*******999999***********9..799***************999988888889************************9755559******* PP Peptidase_M28 90 lnlDmigsggkallf................qsgpktsselekylkaaakpvgktlae.dpfqergipgrsDhapfa.kagipaldl......aet 161 +nlD++ +g+ + p++++ ++++ a+++ +++++ +p e sD+apf g+p +dl e FUN_000617-T1 245 VNLDSAVNGNFSFSArgspslkslvyqesmfSKDPYGKDGEGSLFDSWARKYPSASEPgKPSFE-LLGAGSDYAPFChFIGVPSIDLryafksMER 339 *********9999998888888888888887666666666666677777766665433333333.24556******95688********9999999 PP Peptidase_M28 162 kfkeryHtpkDtl 174 + ++yHt +Dt+ FUN_000617-T1 340 SLYPVYHTVHDTF 352 999********97 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 1.1e-08 5.6e-05 35 91 .. 4 56 .. 1 59 [. 0.80 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 1.1e-08 PA 35 GectfaeKvrnAqaaGAagviiynnvegglgapteaggeeleadpitiPavgiskad 91 G+ ++ Kv+nA++ GA+g+++y+++ ++++p+ g +++ ++ +++P++g ++++ FUN_000617-T1 4 GKIFRGNKVENAAKCGASGAVLYSDP--ADYSPE--GINNTFPKTWWLPGTGTQRGT 56 5566799******************9..555555..445556777*******99986 PP >> DDE_Tnp_IS1 IS1 transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.4 7.1e+03 89 119 .. 75 105 .. 73 109 .. 0.79 2 ? 11.7 0.0 6.8e-05 0.35 70 120 .. 393 439 .. 372 450 .. 0.84 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.4 DDE_Tnp_IS1 89 iernnltlrtrlkrlarkslsfsksvelhek 119 i r n + + l+r+ + +++ +ve+ ++ FUN_000617-T1 75 IYRLNRNETNTLARIPAQVITYNDAVEFLKR 105 5577777888999999999999999998665 PP == domain 2 score: 11.7 bits; conditional E-value: 6.8e-05 DDE_Tnp_IS1 70 yerelkkdkhliskiytqriernnltlrtrlkrlarkslsfsksvelhekv 120 e+ +k++++++ k yt +++ n+tl k lar +fsk v+ ek FUN_000617-T1 393 LEKAMKGNLKVLEKDYTSLLQKGNVTL----KHLAREVETFSKNVDAFEKR 439 68899********************97....57999**********99863 PP >> Mating_N Mating-type protein beta 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 7.9e-05 0.41 16 53 .. 399 436 .. 387 464 .. 0.87 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7.9e-05 Mating_N 16 qtLdalrkdFfssLrgdsealstFlsawskfdellqsc 53 L+ l+kd+ s+L++++ +l++++++ ++f++ ++ FUN_000617-T1 399 GNLKVLEKDYTSLLQKGNVTLKHLAREVETFSKNVDAF 436 5799**************99***********9998875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (538 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 796 (0.0311607); expected 510.9 (0.02) Passed bias filter: 789 (0.0308867); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.39u 0.37s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5170.28 // Query: FUN_000617-T2 [L=471] Description: FUN_000617 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-27 95.2 0.0 6.5e-27 94.4 0.0 1.4 1 TFR_dimer Transferrin receptor-like dimerisation domain 1.4e-20 74.3 0.0 3.5e-20 73.0 0.0 1.6 1 Peptidase_M28 Peptidase family M28 ------ inclusion threshold ------ 0.067 14.0 0.0 0.29 12.0 0.0 2.0 2 DDE_Tnp_IS1 IS1 transposase 0.19 12.3 0.0 0.34 11.5 0.0 1.3 1 Mating_N Mating-type protein beta 1 Domain annotation for each model (and alignments): >> TFR_dimer Transferrin receptor-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 94.4 0.0 1e-30 6.5e-27 2 120 .. 351 466 .. 350 467 .. 0.95 Alignments for each domain: == domain 1 score: 94.4 bits; conditional E-value: 1e-30 TFR_dimer 2 sleplkkaiekfkkaaeefdkwakkweevveasgkessllavrevNdklmlferafldpeglpgrpwfkHvvfapglwtgyagatFPgirdaiea. 96 +l++l + +e+f+k++++f+k+++ + + ++ +vr++Nd++m +eraf+ p+glpgr + v+fap+ ++ y++atFPgi+da+++ FUN_000617-T2 351 TLKHLAREVETFSKNVDAFEKRKAMGT-------DLNNFAQVRMLNDQMMSLERAFIWPNGLPGRVLTRQVLFAPQMHNVYGSATFPGITDALFDi 439 789999999999999999999999977.......89******************************************99**************** PP TFR_dimer 97 ...gdweeaqkqisivakaiekaaesL 120 +dw+e++ q+si+ +++++a++L FUN_000617-T2 440 ektNDWKEVKLQVSIAITCVREVAKLL 466 ************************988 PP >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.0 0.0 5.5e-24 3.5e-20 1 174 [. 84 285 .. 84 297 .. 0.85 Alignments for each domain: == domain 1 score: 73.0 bits; conditional E-value: 5.5e-24 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaa....skqqpkrsvrflffdaEEagllGSkafak..skpelkkirav 89 Nvi+++ g++e d+ +l++ H D + G D sg+a+++e++r l + ++p+rs++f ++aEE gl GS +++ ++ +++ ++ FUN_000617-T2 84 NVIGTIIGSEEpDRMVLVGNHRDAWV--FGGVDPSSGTAVMMEMSRGLGElltkTDWRPRRSIVFCSWGAEEYGLIGSYEWVEenRNMLRERAIMY 177 9*******999999***********9..799***************999988888889************************9755559******* PP Peptidase_M28 90 lnlDmigsggkallf................qsgpktsselekylkaaakpvgktlae.dpfqergipgrsDhapfa.kagipaldl......aet 161 +nlD++ +g+ + p++++ ++++ a+++ +++++ +p e sD+apf g+p +dl e FUN_000617-T2 178 VNLDSAVNGNFSFSArgspslkslvyqesmfSKDPYGKDGEGSLFDSWARKYPSASEPgKPSFE-LLGAGSDYAPFChFIGVPSIDLryafksMER 272 *********9999998888888888888887666666666666677777766665433333333.24556******95688********9999999 PP Peptidase_M28 162 kfkeryHtpkDtl 174 + ++yHt +Dt+ FUN_000617-T2 273 SLYPVYHTVHDTF 285 999********97 PP >> DDE_Tnp_IS1 IS1 transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.94 6e+03 89 119 .. 8 38 .. 6 42 .. 0.79 2 ? 12.0 0.0 4.5e-05 0.29 70 120 .. 326 372 .. 303 383 .. 0.85 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.94 DDE_Tnp_IS1 89 iernnltlrtrlkrlarkslsfsksvelhek 119 i r n + + l+r+ + +++ +ve+ ++ FUN_000617-T2 8 IYRLNRNETNTLARIPAQVITYNDAVEFLKR 38 5577777888999999999999999998665 PP == domain 2 score: 12.0 bits; conditional E-value: 4.5e-05 DDE_Tnp_IS1 70 yerelkkdkhliskiytqriernnltlrtrlkrlarkslsfsksvelhekv 120 e+ +k++++++ k yt +++ n+tl k lar +fsk v+ ek FUN_000617-T2 326 LEKAMKGNLKVLEKDYTSLLQKGNVTL----KHLAREVETFSKNVDAFEKR 372 68899********************97....57999**********99863 PP >> Mating_N Mating-type protein beta 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 5.3e-05 0.34 16 53 .. 332 369 .. 320 397 .. 0.87 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 5.3e-05 Mating_N 16 qtLdalrkdFfssLrgdsealstFlsawskfdellqsc 53 L+ l+kd+ s+L++++ +l++++++ ++f++ ++ FUN_000617-T2 332 GNLKVLEKDYTSLLQKGNVTLKHLAREVETFSKNVDAF 369 5799**************99***********9998875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (471 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 674 (0.0263848); expected 510.9 (0.02) Passed bias filter: 653 (0.0255627); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.43s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4546.59 // Query: FUN_000617-T3 [L=759] Description: FUN_000617 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.8e-27 94.1 0.0 1.4e-26 93.3 0.0 1.4 1 TFR_dimer Transferrin receptor-like dimerisation domain 3.7e-20 72.9 0.0 9.5e-20 71.6 0.0 1.7 1 Peptidase_M28 Peptidase family M28 5.8e-11 42.8 0.0 1.5e-10 41.5 0.0 1.6 1 PA PA domain ------ inclusion threshold ------ 0.14 13.0 0.0 0.55 11.1 0.0 2.0 2 DDE_Tnp_IS1 IS1 transposase 0.23 12.0 0.1 0.65 10.6 0.0 1.7 2 Mating_N Mating-type protein beta 1 Domain annotation for each model (and alignments): >> TFR_dimer Transferrin receptor-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.3 0.0 2.8e-30 1.4e-26 2 120 .. 639 754 .. 638 755 .. 0.95 Alignments for each domain: == domain 1 score: 93.3 bits; conditional E-value: 2.8e-30 TFR_dimer 2 sleplkkaiekfkkaaeefdkwakkweevveasgkessllavrevNdklmlferafldpeglpgrpwfkHvvfapglwtgyagatFPgirdaiea. 96 +l++l + +e+f+k++++f+k+++ + + ++ +vr++Nd++m +eraf+ p+glpgr + v+fap+ ++ y++atFPgi+da+++ FUN_000617-T3 639 TLKHLAREVETFSKNVDAFEKRKAMGT-------DLNNFAQVRMLNDQMMSLERAFIWPNGLPGRVLTRQVLFAPQMHNVYGSATFPGITDALFDi 727 789999999999999999999999977.......89******************************************99**************** PP TFR_dimer 97 ...gdweeaqkqisivakaiekaaesL 120 +dw+e++ q+si+ +++++a++L FUN_000617-T3 728 ektNDWKEVKLQVSIAITCVREVAKLL 754 ************************988 PP >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.6 0.0 1.8e-23 9.5e-20 1 174 [. 372 573 .. 372 585 .. 0.85 Alignments for each domain: == domain 1 score: 71.6 bits; conditional E-value: 1.8e-23 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaa....skqqpkrsvrflffdaEEagllGSkafak..skpelkkirav 89 Nvi+++ g++e d+ +l++ H D + G D sg+a+++e++r l + ++p+rs++f ++aEE gl GS +++ ++ +++ ++ FUN_000617-T3 372 NVIGTIIGSEEpDRMVLVGNHRDAWV--FGGVDPSSGTAVMMEMSRGLGElltkTDWRPRRSIVFCSWGAEEYGLIGSYEWVEenRNMLRERAIMY 465 9*******999999***********9..799***************999988888889************************9755559******* PP Peptidase_M28 90 lnlDmigsggkallf................qsgpktsselekylkaaakpvgktlae.dpfqergipgrsDhapfa.kagipaldl......aet 161 +nlD++ +g+ + p++++ ++++ a+++ +++++ +p e sD+apf g+p +dl e FUN_000617-T3 466 VNLDSAVNGNFSFSArgspslkslvyqesmfSKDPYGKDGEGSLFDSWARKYPSASEPgKPSFE-LLGAGSDYAPFChFIGVPSIDLryafksMER 560 *********9999998888888888888887666666666666677777766665433333333.24556******95688********9999999 PP Peptidase_M28 162 kfkeryHtpkDtl 174 + ++yHt +Dt+ FUN_000617-T3 561 SLYPVYHTVHDTF 573 999********97 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.5 0.0 2.9e-14 1.5e-10 3 91 .. 192 277 .. 182 280 .. 0.85 Alignments for each domain: == domain 1 score: 41.5 bits; conditional E-value: 2.9e-14 PA 3 gplVaapndgceasdgssedf........dvkGkivLvqrGectfaeKvrnAqaaGAagviiynnvegglgapteaggeeleadpitiPavgiska 90 ++lV +a++g+ edf +++G+iv+++ G+ ++ Kv+nA++ GA+g+++y+++ ++++p+ g +++ ++ +++P++g +++ FUN_000617-T3 192 ADLV-------YANYGNDEDFvelekrniSCSGRIVIMRYGKIFRGNKVENAAKCGASGAVLYSDP--ADYSPE--GINNTFPKTWWLPGTGTQRG 276 4566.......9999999999********************************************9..555555..445556777*******9998 PP PA 91 d 91 + FUN_000617-T3 277 T 277 6 PP >> DDE_Tnp_IS1 IS1 transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.1 1.1e+04 89 119 .. 296 326 .. 294 330 .. 0.79 2 ? 11.1 0.0 0.00011 0.55 70 120 .. 614 660 .. 595 671 .. 0.84 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.1 DDE_Tnp_IS1 89 iernnltlrtrlkrlarkslsfsksvelhek 119 i r n + + l+r+ + +++ +ve+ ++ FUN_000617-T3 296 IYRLNRNETNTLARIPAQVITYNDAVEFLKR 326 5577777788999999999999999998665 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00011 DDE_Tnp_IS1 70 yerelkkdkhliskiytqriernnltlrtrlkrlarkslsfsksvelhekv 120 e+ +k++++++ k yt +++ n+tl k lar +fsk v+ ek FUN_000617-T3 614 LEKAMKGNLKVLEKDYTSLLQKGNVTL----KHLAREVETFSKNVDAFEKR 660 68899********************97....57999**********99863 PP >> Mating_N Mating-type protein beta 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 1.8 9e+03 19 40 .. 73 92 .. 67 97 .. 0.74 2 ? 10.6 0.0 0.00013 0.65 16 53 .. 620 657 .. 608 684 .. 0.88 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 1.8 Mating_N 19 dalrkdFfssLrgdsealstFl 40 ++++++ ++sL+ ds +++F FUN_000617-T3 73 KQYHEQMVDSLKADS--VKKFS 92 567889999999998..55554 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00013 Mating_N 16 qtLdalrkdFfssLrgdsealstFlsawskfdellqsc 53 L+ l+kd+ s+L++++ +l++++++ ++f++ ++ FUN_000617-T3 620 GNLKVLEKDYTSLLQKGNVTLKHLAREVETFSKNVDAF 657 5799**************99***********9998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (759 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 907 (0.035506); expected 510.9 (0.02) Passed bias filter: 861 (0.0337052); expected 510.9 (0.02) Passed Vit filter: 87 (0.00340575); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.44u 0.39s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 7273.70 // Query: FUN_000618-T1 [L=768] Description: FUN_000618 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-29 102.6 3.3 2.6e-29 102.0 0.0 2.9 2 NOC3p Nucleolar complex-associated protein 6.8e-25 88.5 2.3 1.3e-24 87.5 0.0 2.4 2 CBF CBF/Mak21 family ------ inclusion threshold ------ 0.15 12.1 2.4 11 6.0 0.0 2.8 3 UCH Ubiquitin carboxyl-terminal hydrolase 0.23 11.8 7.6 0.54 10.6 7.6 1.6 1 DUF6474 Family of unknown function (DUF6474) 0.62 10.4 5.0 1.3 9.3 5.0 1.5 1 CemA CemA family Domain annotation for each model (and alignments): >> NOC3p Nucleolar complex-associated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.0 0.0 5.2e-33 2.6e-29 3 92 .] 163 256 .. 161 256 .. 0.97 2 ? -1.1 1.1 0.73 3.7e+03 66 85 .. 418 437 .. 406 471 .. 0.54 Alignments for each domain: == domain 1 score: 102.0 bits; conditional E-value: 5.2e-33 NOC3p 3 keeiaelaskiledPeenikalkrllklaeskd....vtikkLallsllavFkdiiPgYrIrpltekekkekvskevkklrefEqsLlknYkkY 92 + +ia l+++ile+P+e+i +l++l++l+++kd +t++kLa++sll+vFkdiiPgY Ir t+ke++ k+sk+vkklr+fE++Llk+Y+kY FUN_000618-T1 163 RLRIAGLSNRILENPQEHIPELQELCRLCDEKDvdveITTRKLAMVSLLTVFKDIIPGYPIRVPTQKERAVKLSKDVKKLRDFEDGLLKSYQKY 256 668************************99999999999*******************************************************9 PP == domain 2 score: -1.1 bits; conditional E-value: 0.73 NOC3p 66 ekkekvskevkklrefEqsL 85 ++++k +k +++++ E++L FUN_000618-T1 418 KMSKKEKKRRREMKKLENEL 437 33334444444444444433 PP >> CBF CBF/Mak21 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.8 0.3 1.5e+03 58 99 .. 331 368 .. 291 451 .. 0.45 2 ! 87.5 0.0 2.6e-28 1.3e-24 4 167 .] 520 671 .. 517 671 .. 0.86 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.3 CBF 58 pakrvaAFvKRllqlallqappsfivgilylisellkrhppk 99 +++ AFvK + q +l ++++ ++++is+ +kr++ FUN_000618-T1 331 SKQCFDAFVKLFKQDSLG----KVSLEAVKFISKFVKRKQFR 368 444444555544444444....24444444455444433322 PP == domain 2 score: 87.5 bits; conditional E-value: 2.6e-28 CBF 4 alnllfqllssq..k.nldypdFyrkLYelLldprlltsskqa.lflnlldlf...sskalpakrvaAFvKRllqlallqappsfivgilylisel 92 + ++ ++ls+q + n d Fy+ LY++Ll+ + + s+ a +l++l+ + ++k +p +rv FvKRl++++l+ +++ ++++l ++ FUN_000618-T1 520 CALTAIKILSGQgeAlNIDPRGFYNMLYSCLLQVDAGSNSQDAfIVLQCLEEMlkkRRKQVPSQRVSGFVKRLCTVSLH-SQANGALAFLSYVKSF 614 5556666777764324446666*************999999888*******9999889999******************.6*************** PP CBF 93 lkrhppklrsllheeeedeeeeeeeekekeeekgsdpYdprke.erdpeksnAdesslwElellrk.hyhpsVskla 167 l++h+ k+++ll++e + g + + p + + dpe snAd+s+ wEl+llr hyhp V+ +a FUN_000618-T1 615 LQSHT-KVHALLDNE----------------SIGIGLFRP--DvN-DPELSNADSSTAWELALLRTgHYHPLVKMIA 671 **888.9******99................567899***..556.******************655*****98765 PP >> UCH Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.2 0.57 2.9e+03 82 82 .. 414 414 .. 309 474 .. 0.62 2 ? 6.0 0.0 0.0022 11 19 131 .. 490 600 .. 481 606 .. 0.78 3 ? 5.3 0.0 0.0036 19 200 236 .. 669 705 .. 609 723 .. 0.84 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.57 x RF UCH 82 e 82 + FUN_000618-T1 414 K 414 1 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0022 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 19 LlsipelrdlllrieeekedseeekeinllkalaklfkelqkkkksssvkPkklkkllgklneefs.gykqqDaqEfleflLdqlheklnkwekas 113 L++i+ + dl+ i++ ++++ + l +al+ + k l + + +++P+ + ++l ++ + g+++qDa +l+ l + l++ ++ s FUN_000618-T1 490 LINIEFFNDLMAAIQSLLNNENLTLRETLNCALTAI-KILSGQGEALNIDPRGFYNMLYSCLLQVDaGSNSQDAFIVLQCLEEMLKKRRKQ--VPS 582 778888888888887777777666555556555544.45666778899**********999888766999****87777777777776666..899 PP xxxxxxxxxxxxxxxxxx RF UCH 114 keeeslitdlFrgqlksr 131 ++ + +++l +++l s+ FUN_000618-T1 583 QRVSGFVKRLCTVSLHSQ 600 999999999999888876 PP == domain 3 score: 5.3 bits; conditional E-value: 0.0036 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 200 LvavvvHsGslssGHYiayikaeeknkWvkfdDekvs 236 +a v +G +s+GH+ a+++++ + W ++d ++++ FUN_000618-T1 669 MIAHHVAQGAPSKGHFSAIMRKSPEALWQEYDSSEMK 705 4566677999***********999999*****99876 PP >> DUF6474 Family of unknown function (DUF6474) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 7.6 0.0001 0.54 10 96 .. 394 481 .. 385 490 .. 0.67 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0001 DUF6474 10 sRaerkaeakalkakakleaklaaknerkrekalakaekkllkaekkalkakekaeekl...kaaaeakklsaakvkrylgvarllaPvl 96 + +++ e+k k+k + e kl+ k +k++k+ ++e k l++e+k+ +a e +++k+ + + ++ +v +++g ll Pvl FUN_000618-T1 394 NEKKSVVELKLEKKKHRIEKKLKGKMSKKEKKR--RREMKKLENELKETEAVESHQKKAklqTEILKFVFVTYFRVLKTIGHCPLLSPVL 481 244555678888888888888888888666555..4466666778888888888888884333334444557778888888888888887 PP >> CemA CemA family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 5.0 0.00026 1.3 45 123 .. 387 465 .. 352 473 .. 0.82 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00026 CemA 45 eiflnkeleeealeelkefeekleleeligeapelseeeieeelkekaeelakeyreesaeaikniladivslialvvl 123 +l+k+ e++ + elk +++k ++e+ ++ + + +e++ + e+k+ +el+++ + es++ +++ ++i+ ++ ++ + FUN_000618-T1 387 IQALKKSNEKKSVVELKLEKKKHRIEKKLKGKMSKKEKKRRREMKKLENELKETEAVESHQKKAKLQTEILKFVFVTYF 465 4467899999****************************************************99***999998766554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (768 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2761 (0.108084); expected 510.9 (0.02) Passed bias filter: 896 (0.0350754); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.44u 0.39s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 7454.83 // Query: FUN_000619-T1 [L=185] Description: FUN_000619 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.9e-06 26.2 0.0 1.6e-05 25.5 0.0 1.5 1 Death Death domain ------ inclusion threshold ------ 0.18 12.4 0.2 0.39 11.3 0.2 1.5 1 DUF7337 Family of unknown function (DUF7337) 0.22 12.2 0.1 0.34 11.6 0.1 1.2 1 SoFic-like_C Protein adenylyltransferase SoFic-like, C-termi Domain annotation for each model (and alignments): >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 1.8e-09 1.6e-05 18 85 .. 26 89 .. 8 90 .. 0.83 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.8e-09 Death 18 WreLark...lglseeeideiesenrdlrsqtyelLklWearegknatvgnLleaLrklgrrdaaekikai 85 W++L+ k +s+++++eie+++ s++ lL+ +a ++ +v nL++aL+k+g a+++ik+ FUN_000619-T1 26 WKKLMLKgfsHIYSQDDVNEIEQKP----SPAIILLNDLVA---REESVKNLMRALEKIGNLQAISIIKNG 89 7777754222579************....************...789*********************985 PP >> DUF7337 Family of unknown function (DUF7337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.2 4.6e-05 0.39 35 58 .. 54 77 .. 43 79 .. 0.85 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 4.6e-05 DUF7337 35 LvaLndLnvRkEsLKEleeAiEKL 58 + LndL R Es+K+l A+EK+ FUN_000619-T1 54 IILLNDLVAREESVKNLMRALEKI 77 5679******************96 PP >> SoFic-like_C Protein adenylyltransferase SoFic-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 4e-05 0.34 14 74 .. 35 94 .. 27 96 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4e-05 SoFic-like_C 14 pkiYskELveliFeqpYcrienlveagiakRqtaskyLkeLveigvLeeekvGreklfinp 74 ++iYs++ v+ i ++p i l ++ +a+ ++ + +++L++ig L+ +++ ++ l+ + FUN_000619-T1 35 SHIYSQDDVNEIEQKPSPAIILL-NDLVAREESVKNLMRALEKIGNLQAISIIKNGLYHHY 94 78**********99999888655.77888888889999********************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 708 (0.0277158); expected 510.9 (0.02) Passed bias filter: 558 (0.0218438); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1817.33 // Query: FUN_000620-T1 [L=951] Description: FUN_000620 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-127 426.3 45.0 2.5e-127 425.9 45.0 1.2 1 PigN Phosphatidylinositolglycan class N (PIG-N) 1.2e-10 42.0 0.4 3.6e-10 40.4 0.4 1.7 1 Phosphodiest Type I phosphodiesterase / nucleotide pyroph 5.8e-05 23.2 0.1 0.00012 22.1 0.1 1.5 1 Metalloenzyme Metalloenzyme superfamily ------ inclusion threshold ------ 0.14 11.5 0.1 0.22 10.9 0.1 1.2 1 Alk_phosphatase Alkaline phosphatase Domain annotation for each model (and alignments): >> PigN Phosphatidylinositolglycan class N (PIG-N) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 425.9 45.0 3.9e-131 2.5e-127 1 456 [] 433 906 .. 433 906 .. 0.90 Alignments for each domain: == domain 1 score: 425.9 bits; conditional E-value: 3.9e-131 PigN 1 eGLrYlqtYdrlfLrtivtlgylGWiayllltvlklh..vlsekkk...skkskkstllglkflsllllvllllllllqkspltyylYlllPvyfw 91 eGL+Y+q+Ydr+fL ++vtlg++GWi++++l +++ h vl+e++k +++++ + +++ +++++++l ++lll++k+p++yy Y+llP++fw FUN_000620-T1 433 EGLNYYQNYDRVFLNIVVTLGFFGWIVCIVLQIIEDHsdVLKETQKikhKHSNTVIKAPTVDSVTFVIAILGVILLLIEKAPWMYYTYCLLPLVFW 528 8******************************8885551155555555442222223333456666677777999********************** PP PigN 92 eevlaerkilkeglkellkevkssllkkllillllivvvlellvlsffhreilsvlfvllalwplllgtsflkknsllsllWlllclllsvFtll. 186 + + ++ +++++ +k+++ ++ +++++l +lll v+ le+lvlsff+reilsv++v++++wp++ ++l+ ++ +++W++lc++l+vF++l FUN_000620-T1 529 NRIGKKLHVIYATFKYISLRK---AARRVLFTLLLGVLSLEILVLSFFKREILSVGLVCFSFWPFT---TTLTDCRSSLACWTVLCFALAVFPILp 618 **********99999999988...7888888888******************************99...46788999******************6 PP PigN 187 pvvkkenltlillggllilllglllllfeksl......skkslsralllqvllillallvtrssvlslqakqglpllnqvvsWiilvlsllslpll 276 v+++ n+ l++++g++il++ l+ll++ s+ + +++ + l++q+ll+ al++++++++slq+k glp++nq sW+il++s+l lpl+ FUN_000620-T1 619 VVGREANYFLVTAAGVVILVVFSLMLLYSASIsrqihiEIDNYLSILIFQFLLVTFALYIINATTSSLQRKLGLPVINQYGSWTILLSSFL-LPLI 713 666667*************99999976555556777888888888888*******************************************.**** PP PigN 277 setkplsRlllifltfaptfilLsisyEsLFyvllsltlllwieleeelke.............eeskkeeeeskksekkkkkskrkltlsdlRia 359 +++++ Rl +++++++++f+l+s+ yE+LF ++lsl++ +w+ e++ + +s+++ + + +e + + rkltl+dlRia FUN_000620-T1 714 NSSNLVVRLWSVVIALSSVFLLMSTAYEGLFLLVLSLLMGTWLLCEHKRSGktlntlletrlssPNSASQPAWKVLTEGLDAATARKLTLEDLRIA 809 ***********************************************6655**********99966666777777777788889************ PP PigN 360 lfflfflqvaFFGtGniasissFslesvyrfipvfspflmgaLlllKlliPfvlvsaalgalnkrlrlppsslfllvllisDvmtLnFfflVkdeG 455 +ff+ff++vaFFGtGniasi+sF++ svy+f++vfspf+mg Lll+K+liPfv+v++a+ a+ l +p sl+l+vl+++D m+L+Ff+lVkd+G FUN_000620-T1 810 YFFVFFIVVAFFGTGNIASINSFDPASVYCFLTVFSPFIMGGLLLCKVLIPFVVVTCAFDAIHVVLSIPVESLVLVVLVMTDLMGLHFFYLVKDSG 905 ************************************************************************************************ PP PigN 456 S 456 S FUN_000620-T1 906 S 906 9 PP >> Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.4 0.4 5.7e-14 3.6e-10 1 223 [. 50 271 .. 50 287 .. 0.74 Alignments for each domain: == domain 1 score: 40.4 bits; conditional E-value: 5.7e-14 Phosphodiest 1 llvislDGfradylerl....e.ltpnlaaLakegvsapnlrpvfPtlTfpnhytlvTGlyPesHGIvgNtfydpktgey.efstsdeekpkwwqg 90 l++++ DG+rad +++ + ++p l+ L+++ s ++ +Pt++ p+h++l+ G y + + ++ k + + + st +e+++ w g FUN_000620-T1 50 LVLFVADGLRADKFFEVdeggNtRAPYLRDLLAKKASWGVSHTRVPTESRPGHVALIAGFYEDVSAVAK-GW---KENPVeFDSTFNESRNTWAWG 141 699*************9987626*******99977777779***********************99999.33...444442333333333567566 PP Phosphodiest 91 epiwvtaakagvkaaalfwpgsevdysty..gtppeylkddynasvpfed.rvdtavlsewldlpeakaa......erpdlllvyleepDragHkf 177 +p + + +g ++ ++++ ++ d++++ + + +++ +d+ v+ ++++ ++ ++ ++ ++++l +D+ gH + FUN_000620-T1 142 SPDILPMFAKGA-SGGHVFTSMYKDIAEDfgDEDAS----------KLDAwVFDE-VK-QFFASAKNNNTlkemlsQDQIIFFLHLLGIDTNGHAH 224 676677777777.55555666777776432222222..........222212222.33.333333322223444556667999************* PP Phosphodiest 178 GpdspeveealrrvDkaigeLlealker.glkeetnvivvSDHGmap 223 p s+e+ ++++ vDk i+++ ++++ + + +t+ i+++DHGm++ FUN_000620-T1 225 RPTSSEYLKNIAVVDKGIQQIEQEIEMFyNHDGQTAYIMTADHGMTN 271 **************************9999***************97 PP >> Metalloenzyme Metalloenzyme superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.1 2e-08 0.00012 127 227 .. 187 296 .. 151 331 .. 0.76 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 2e-08 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxx.xxxxxx RF Metalloenzyme 127 pemsakevtdkllealeegkydfvvvnikntDevGHtgdv..eakvkaieavDerlkelldale.....keddlliitADHgnaeemkd.TsHtre 214 ++ a ++ +++l+++ +++ ++++++ +D GH+ + +++ k i vD+ ++++ +++e + ++ +i+tADHg + T H e FUN_000620-T1 187 KQFFASAKNNNTLKEMLSQDQIIFFLHLLGIDTNGHAHRPtsSEYLKNIAVVDKGIQQIEQEIEmfynhDGQTAYIMTADHGMTNWGSHgTGHPHE 282 4556677888999999999999**********9999887622789***********9998877533332456789*******77766555999988 PP xx.xxxxxxxxxxx RF Metalloenzyme 215 pV.Pvliygkgvrk 227 P++ +g gv+ FUN_000620-T1 283 TLtPLVAWGAGVKG 296 64499999999886 PP >> Alk_phosphatase Alkaline phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 3.4e-05 0.22 249 313 .. 201 269 .. 193 290 .. 0.77 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 3.4e-05 Alk_phosphatase 249 rlLsknekGFfLlVEGgrIDhahHendavgalsEvveldeAvkrale....lakkekdtlvvvTaDHsh 313 ++Ls+++ FfL G +H + + l+ + +d+ +++ + + +++ +t + TaDH FUN_000620-T1 201 EMLSQDQIIFFLHLLGIDTNGHAHRPTSSEYLKNIAVVDKGIQQIEQeiemFYNHDGQTAYIMTADHGM 269 689************9555555555566678********9998875423325556************76 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (951 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1369 (0.0535917); expected 510.9 (0.02) Passed bias filter: 624 (0.0244275); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.40u 0.42s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 9224.38 // Query: FUN_000621-T1 [L=682] Description: FUN_000621 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-250 833.0 3.0 2e-250 832.6 3.0 1.1 1 HSP70 Hsp70 protein 5.3e-17 62.1 0.1 4.2e-15 55.9 0.0 2.2 2 MreB_Mbl MreB/Mbl protein 3.2e-05 24.4 0.0 0.0022 18.4 0.0 2.6 3 FGGY_C FGGY family of carbohydrate kinases, C-termin 0.0036 17.1 0.4 0.026 14.2 0.1 2.3 2 Hydantoinase_A Hydantoinase/oxoprolinase ------ inclusion threshold ------ 0.011 15.6 0.0 0.03 14.3 0.0 1.6 1 TmcA_N tRNA(Met) cytidine acetyltransferase TmcA, N- 0.18 12.3 0.0 0.64 10.5 0.0 2.0 1 ParM_N Plasmid segregation protein ParM, C-terminal 0.55 11.1 5.5 30 5.5 0.1 3.8 3 FtsA Cell division protein FtsA 2.1 9.8 4.3 1.1 10.7 0.3 2.7 3 PWP3A-B_N PWWP domain-containing DNA repair factor 3A/B Domain annotation for each model (and alignments): >> HSP70 Hsp70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 832.6 3.0 6.2e-254 2e-250 1 597 [. 8 614 .. 8 616 .. 0.97 Alignments for each domain: == domain 1 score: 832.6 bits; conditional E-value: 6.2e-254 HSP70 1 viGiDLGttnscvavmeggkievianeegnrttPsvvaftkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengk 96 +iGiDLGtt+scv+v+++gk+e+ian++gnrttPs+vaf+++erl+GeaAk+qa+ np++t+f++KrliGrkf+dp+vq++ +++p++vv++ gk FUN_000621-T1 8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSFVAFNETERLIGEAAKNQAALNPSHTIFDAKRLIGRKFDDPTVQSDRENWPFQVVNE-YGK 102 59****************************************************************************************99.9** PP HSP70 97 alveveaage..kfspeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd.kernvl 189 ++++v+ +g+ +spe++s+mvL k+ketaeaylg++v++avitvPaYfnd+qRqatkdAg iAGLnv Ri+NepTAaalaYGldk+ e+nvl FUN_000621-T1 103 PKIRVQSKGDwkWLSPEEVSSMVLIKMKETAEAYLGQTVKNAVITVPAYFNDSQRQATKDAGVIAGLNVKRIINEPTAAALAYGLDKNLqGEKNVL 198 ********999789*************************************************************************9658***** PP HSP70 190 vyDlGggtfdvSileleeG.vfevkaTngDthlGGedfDealvdylveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvde 284 ++DlGggtfdvS+l++++G fev++T+gDthlGGedfD++lvd++++ef++k + dl+ ++ka++rl++a e+aK++LSs +t++++e++++ + FUN_000621-T1 199 IFDLGGGTFDVSVLTIDQGsLFEVRSTAGDTHLGGEDFDNRLVDHFAAEFQRKFNTDLKGNPKAIHRLRTASERAKRSLSS--NTQASIEVDSLAA 292 *******************669***********************************************************..999********99 PP HSP70 285 dgkdlseklsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsksvnpDeavaiGaAvqagvlsge. 378 g d+++k++Rakfeel++dl++ +lepvekal+dakl+k+ i+e+vlvGGstRiPkvq+l++e+f+ k+++k++npDeava+GaAvqa++lsg+ FUN_000621-T1 293 -GIDFHTKITRAKFEELCHDLFSSCLEPVEKALRDAKLEKSAIHEIVLVGGSTRIPKVQQLLEEFFDgKKLNKTINPDEAVAYGAAVQAAILSGTr 387 .*****************************************************************88**************************96 PP HSP70 379 .eevkdllllDvtpLslgietlggvmtkliernttiptkks.qvfstaadnqtaveikvlqgerelakdnkllgkfeldgippaprGvpqieVtfd 472 + d+lllDv pLslgiet+gg+mtk+iern ipt+ + + fst+adnqt v+i+v++ger+++kdn+llg+fel+gippaprGvp+ieV+fd FUN_000621-T1 388 gDGIGDILLLDVAPLSLGIETAGGIMTKVIERNSRIPTSMTrKEFSTYADNQTGVTIQVYEGERAMTKDNNLLGRFELTGIPPAPRGVPKIEVSFD 483 66899**********************************9999***************************************************** PP HSP70 473 idanGiltvsakdkgtgkeeeitieaseg.lseeeiekmvkdaeesaeedkkkkeaieakneaeelvyslekkleee..kekvseaek....ekve 561 idanGil vsakd+ tg+++ iti++++g ls++eie+mv dae+++e+d+k++e+i a+n++e+++ys++++ e+ k+k++ + +k + FUN_000621-T1 484 IDANGILAVSAKDQCTGRSNAITITNDTGrLSKDEIERMVADAEKYKEDDQKQREEIAARNSLENYLYSVKHATENPnlKDKLNTTDSetltSKTQ 579 *****************************9******************************************999888899999888855666777 PP HSP70 562 eaieelkeeleeedkeeieakteelkkvvekiaekl 597 e +e+l+++ ++++ke++e+k ++lk+v+++i++kl FUN_000621-T1 580 EVMEWLENN-STAEKEDYERKEKDLKEVCSPIMSKL 614 777788777.57779****************99876 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.0 0.0 0.0082 26 3 37 .. 8 51 .. 6 68 .. 0.58 2 ! 55.9 0.0 1.3e-18 4.2e-15 92 316 .. 140 377 .. 119 384 .. 0.77 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.0082 MreB_Mbl 3 dlgiDLGtantlv..yvkgkgivl.ne......psvvAiekktk 37 +giDLGt+ v +++gk ++ n+ ps vA++++++ FUN_000621-T1 8 AIGIDLGTTYSCVgvFQHGKVEIIaNDqgnrttPSFVAFNETER 51 69*******99983355555433313222223366666666544 PP == domain 2 score: 55.9 bits; conditional E-value: 1.3e-18 MreB_Mbl 92 skprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGagl..pveepsgnmvvdiGggttevavisl..ggivtsks....vrvaGde 179 + ++ vi+vP ++ +r+A k+a aG + +i+ep aAA+ gl +++ + ++ d+Gggt +v+v+++ g++ + +s +++G++ FUN_000621-T1 140 TVKNAVITVPAYFNDSQRQATKDAGVIAGLNVKRIINEPTAAALAYGLdkNLQGEKNVLIFDLGGGTFDVSVLTIdqGSLFEVRStagdTHLGGED 235 456789************************************9966662268889999**************98633667666652233689**** PP MreB_Mbl 180 ldeaiikyirkky....nlli.Gerta.eeikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealkepvsaiveavkevLektppeL 268 +d+ ++++ ++ n + G+ +a +++++ a + +++ + +i+ l+ g+ +++++ ++ +e ++ +s+ +e v+++L++++ e FUN_000621-T1 236 FDNRLVDHFAAEFqrkfNTDLkGNPKAiHRLRTASERAKRSLSSNtQASIEVDSLAAGIDFHTKITRAKFEELCHDLFSSCLEPVEKALRDAKLEK 331 ******99866551100544423333213444444444433333358999999*************************************998876 PP MreB_Mbl 269 aadivdrgivltGGgallkgldkllseetg.lpvkvaedpltcvakGtg 316 +a i + ivl+GG++ + +++ll+e ++ + + + +p ++va G++ FUN_000621-T1 332 SA-I--HEIVLVGGSTRIPKVQQLLEEFFDgKKLNKTINPDEAVAYGAA 377 65.3..569******************9962567788899999999986 PP >> FGGY_C FGGY family of carbohydrate kinases, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.0 6.9e-07 0.0022 111 196 .. 270 382 .. 243 384 .. 0.82 2 ? -3.5 0.0 3.4 1.1e+04 70 110 .. 423 462 .. 412 470 .. 0.67 3 ? 3.1 0.0 0.032 1e+02 41 88 .. 572 637 .. 570 672 .. 0.66 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 6.9e-07 FGGY_C 111 i....iGlsssttlaelaraileglalqlrqilealeke.....................eghpidtiavvGGgskndlllqllAdalg.lpvevp 180 + lss+t+++ ++ ++ g+ + ++ ++e+ e+++i i++vGG ++ + ++qll + ++ +++ + FUN_000621-T1 270 SerakRSLSSNTQASIEVDSLAAGIDFHTKITRAKFEELchdlfssclepvekalrdaklEKSAIHEIVLVGGSTRIPKVQQLLEEFFDgKKLNKT 365 4555577888888888888888888888888888887778888888888888889999989***************************88777666 PP FGGY_C 181 qt.deatalGaallaav 196 + dea+a Gaa+ aa+ FUN_000621-T1 366 INpDEAVAYGAAVQAAI 382 666************97 PP == domain 2 score: -3.5 bits; conditional E-value: 3.4 FGGY_C 70 veeslaelaaaaaaadaggvlfvpdfsgerapgadpdargt 110 + + + +++ + ad++ +++ + gera d+++ g FUN_000621-T1 423 I-PTSMTRKEFSTYADNQTGVTIQVYEGERAMTKDNNLLGR 462 4.455556666777777777778888888888888777665 PP == domain 3 score: 3.1 bits; conditional E-value: 0.032 FGGY_C 41 eggqsaagsllawllqel.elreeladagnv.................eeslaelaaaaaaadagg 88 e +s+++++++wl ++ +++e+ ++++++ +++ +++ ++++++d g FUN_000621-T1 572 ETLTSKTQEVMEWLENNStAEKEDYERKEKDlkevcspimsklhgqqnCQRQQSNFQRQQSSDSDG 637 567899*********996655555555555577776666666666666555555555555555555 PP >> Hydantoinase_A Hydantoinase/oxoprolinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.23 7.2e+02 80 106 .. 7 33 .. 3 47 .. 0.85 2 ! 14.2 0.1 8.3e-06 0.026 51 96 .. 167 212 .. 122 229 .. 0.78 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.23 Hydantoinase_A 80 klIlfDmGGTstDislikdgevevete 106 ++I++D+G T + ++++++g+ve+ + FUN_000621-T1 7 PAIGIDLGTTYSCVGVFQHGKVEIIAN 33 68********************98765 PP == domain 2 score: 14.2 bits; conditional E-value: 8.3e-06 Hydantoinase_A 51 rkkpvetilSGPaaGvvgaaelsklegeeklIlfDmGGTstDisli 96 + v+ i+ P a + ++ +l+ge+++++fD+GG ++D+s++ FUN_000621-T1 167 AGLNVKRIINEPTAAALAYGLDKNLQGEKNVLIFDLGGGTFDVSVL 212 55567788899999999999999********************986 PP >> TmcA_N tRNA(Met) cytidine acetyltransferase TmcA, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 9.3e-06 0.03 28 91 .. 87 152 .. 76 157 .. 0.82 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 9.3e-06 TmcA_N 28 sgdeswclellervle...kekkkgsvlyvshseledieledlsyskaeklLGqeydllvlDatdgf 91 s+ e+w +++ +++++ + ++kg++ ++s++e ++ + ++ae +LGq+++ +v+ + f FUN_000621-T1 87 SDRENWPFQVVNEYGKpkiRVQSKGDWKWLSPEEVSS-MVLIKMKETAEAYLGQTVKNAVITVPAYF 152 667788888777787788999****************.455555567899**********9876555 PP >> ParM_N Plasmid segregation protein ParM, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.0002 0.64 5 40 .. 195 233 .. 191 256 .. 0.81 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.0002 ParM_N 5 eslLivDlGGttLDvakv...rgklegiskvkgdskiGv 40 +Li DlGG t Dv+ + +g l ++ + gd ++G FUN_000621-T1 195 KNVLIFDLGGGTFDVSVLtidQGSLFEVRSTAGDTHLGG 233 578*************87334588999999999999885 PP >> FtsA Cell division protein FtsA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.0094 30 2 20 .. 10 28 .. 9 56 .. 0.88 2 ? 4.6 0.1 0.017 55 4 104 .. 201 358 .. 198 375 .. 0.61 3 ? 0.8 0.2 0.27 8.8e+02 33 87 .. 507 541 .. 498 641 .. 0.66 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0094 xxxxxxxxxxxxxxxxxxx RF FtsA 2 liDiGggttdiavfedgal 20 +iD+G++ ++ vf++g++ FUN_000621-T1 10 GIDLGTTYSCVGVFQHGKV 28 8***************965 PP == domain 2 score: 4.6 bits; conditional E-value: 0.017 xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxx......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 4 DiGggttdiavfedgalrhtevipv......ggngitkd......................iakglrtaveeAErlkikyGsalaseadeeeeevp 71 D+Gggt d++v ++ ev gg+ + + + + lrta e A+r FUN_000621-T1 201 DLGGGTFDVSVLTIDQGSLFEVRSTagdthlGGEDFDNRlvdhfaaefqrkfntdlkgnpkAIHRLRTASERAKRSL------------------- 277 88888888888876654444444443344557777777766666666666666666666666666666666666666................... PP xxxxxxxxxxxxxxxx..................................................xxxxxxxxxxxxxxxxx RF FtsA 72 gvggrepreisrkela..................................................ggsalkglkelaeralg 104 +++++ +i+ + la g++ ++++++l+e+ ++ FUN_000621-T1 278 --SSNTQASIEVDSLAagidfhtkitrakfeelchdlfssclepvekalrdakleksaiheivlvgGSTRIPKVQQLLEEFFD 358 ..112222222222223333333333444557779999999999999999999999999999999999999999999999983 PP == domain 3 score: 0.8 bits; conditional E-value: 0.27 xxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 33 itkd....iakglrtaveeAErlkikyGsalaseadeeeeevpgvggrepreisrkela 87 it+d + + v++AE+ k +++++ +r+e+a FUN_000621-T1 507 ITNDtgrlSKDEIERMVADAEKYK-------EDDQK-----------------QREEIA 541 566644433445667777888888.......11111.................222222 PP >> PWP3A-B_N PWWP domain-containing DNA repair factor 3A/B, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 8 2.6e+04 43 63 .. 104 125 .. 92 136 .. 0.68 2 ? 10.7 0.3 0.00036 1.1 49 88 .. 509 548 .. 494 554 .. 0.90 3 ? -2.3 0.2 4 1.3e+04 47 77 .. 567 596 .. 562 623 .. 0.60 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 8 PWP3A-B_N 43 kikvkst.dvkplekseieaia 63 ki+v+s+ d k l+ +e+++++ FUN_000621-T1 104 KIRVQSKgDWKWLSPEEVSSMV 125 6777765467777777777765 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00036 PWP3A-B_N 49 tdvkplekseieaiasslaeqseksaeaveelayrraLkv 88 +d+ l+k eie++++ +++ +e+ ++++ee+a r++L FUN_000621-T1 509 NDTGRLSKDEIERMVADAEKYKEDDQKQREEIAARNSLEN 548 68899********************************975 PP == domain 3 score: -2.3 bits; conditional E-value: 4 PWP3A-B_N 47 kstdvkplekseieaiasslaeqseksaeav 77 ++td ++l+ + +++++ l+++s++++e FUN_000621-T1 567 NTTDSETLTSK-TQEVMEWLENNSTAEKEDY 596 55566666543.3444444444444443333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (682 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1655 (0.0647876); expected 510.9 (0.02) Passed bias filter: 548 (0.0214523); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6599.82 // Query: FUN_000624-T1 [L=252] Description: FUN_000624 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-11 43.4 11.5 8.5e-11 42.5 11.5 1.4 1 CECR6_TMEM121 CECR6/TMEM121 family Domain annotation for each model (and alignments): >> CECR6_TMEM121 CECR6/TMEM121 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.5 11.5 3.3e-15 8.5e-11 5 191 .. 74 251 .. 67 252 .] 0.84 Alignments for each domain: == domain 1 score: 42.5 bits; conditional E-value: 3.3e-15 CECR6_TMEM121 5 laWllYv.ivlvikvvlifknsiadelkeldv.fgkkllkvllslsvpllflllvaihhaeeprskrklylkslllsvvldLlDslelleiLleke 98 + W lYv v+v+ v+ if +++ +e +v +g ++++++++ + p+l lll + ++ + +++ +++l + +v+dL+D +e+l+ l+ + FUN_000624-T1 74 FGWKLYVgCVFVPNVICIFGIAFSF--EEDKVpYGVNGITLTVCAT-PILLLLLLITADDSFSSRNHRDLVRNLSILMVFDLIDGIEMLDSTLKGN 166 67****746799*********9887..445555*************.99988888888888888899999*************************9 PP CECR6_TMEM121 99 stnLplkleglvlvvacinlflPvlaLyelsvskvsqkvkivslkklyallslllvnvpllviRlllffrdnrdvsifllKNvlailikllei 191 s + +++++ a++ ++l + ++e++ + + ++++ + + ++++++n ++l++R+ + + + + ++KN +ai++ ++++ FUN_000624-T1 167 SYG---IHKSFLILGAVMIIVLSSFQMAEYKFVGGELMEQPIYTITVIRHIFVIILNLVFLIVRVKV-----SRSILIIFKNCMAIILSVIQM 251 755...23455555666667999********999988888888888899999999*********844.....455677899*99999998875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (252 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1086 (0.0425132); expected 510.9 (0.02) Passed bias filter: 299 (0.0117048); expected 510.9 (0.02) Passed Vit filter: 9 (0.000352319); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2493.90 // Query: FUN_000627-T1 [L=258] Description: FUN_000627 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-11 44.9 10.0 3.4e-11 43.8 10.0 1.4 1 CECR6_TMEM121 CECR6/TMEM121 family ------ inclusion threshold ------ 0.13 13.5 0.7 0.13 13.5 0.7 4.0 5 YccF Inner membrane component domain Domain annotation for each model (and alignments): >> CECR6_TMEM121 CECR6/TMEM121 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.8 10.0 2.6e-15 3.4e-11 5 191 .. 74 251 .. 71 253 .. 0.85 Alignments for each domain: == domain 1 score: 43.8 bits; conditional E-value: 2.6e-15 CECR6_TMEM121 5 laWllYv.ivlvikvvlifknsiadelkeldvfgkkllkvllslsvpllflllvaihhaeeprskrklylkslllsvvldLlDslelleiLlekes 99 + W lYv v+v+ v+ if +i+ ++++ + ++l+++++ + p+l lll + ++ +++++ ++l + +v dL+D +e+l+ l+ +s FUN_000627-T1 74 FGWKLYVgCVFVPNVICIFGIAISF-EEDKLPYSVNGLTLTVCAT-PILLLLLLITADDSFSSKNHRDLFRNLSILMVSDLIDGIEMLDSTLKGNS 167 67****746799**********988.4455559************.9998888888888888888999999999999*****************97 PP CECR6_TMEM121 100 tnLplkleglvlvvacinlflPvlaLyelsvskvsqkvkivslkklyallslllvnvpllviRlllffrdnrdvsifllKNvlailikllei 191 + +++++ a++ ++l + ++e++ + + ++++ + + + ++++++n ++l++R+ + + + + ++KN +ai++ ++ei FUN_000627-T1 168 YG---IHKSFLILGAVMIIVLSSFQMAEYKFVGGELMEQPIYTTTVIRHIFVIILNLVFLIVRVKV-----SRSILIIFKNCMAIILSVIEI 251 55...2345555566666799**********9999999*************************844.....45667789*********9998 PP >> YccF Inner membrane component domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 1.8 0.17 2.2e+03 10 47 .. 9 46 .. 6 46 .. 0.71 2 ? 1.0 1.1 0.079 1e+03 18 37 .. 38 57 .. 34 62 .. 0.74 3 ? 13.5 0.7 1e-05 0.13 8 34 .. 72 98 .. 68 103 .. 0.93 4 ? -2.0 0.1 0.7 8.9e+03 19 30 .. 175 186 .. 173 195 .. 0.55 5 ? -3.0 1.4 1.4 1.7e+04 30 30 .. 226 226 .. 211 255 .. 0.59 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.17 YccF 10 fGwwlalghllaglllcitiigipygrqlfklakyllw 47 +G +l + +++ l+ ++ l+kl+ ++l+ FUN_000627-T1 9 CGRVLLFTLFFIQLVAFFSFQMTGNVNSLWKLIALALY 46 56666666666677777666777788888999998886 PP == domain 2 score: 1.0 bits; conditional E-value: 0.079 YccF 18 hllaglllcitiigipygrq 37 + l++l+l+++i+g+ g+ FUN_000627-T1 38 WKLIALALYFCIVGVYSGIF 57 66788888888888776665 PP == domain 3 score: 13.5 bits; conditional E-value: 1e-05 YccF 8 ilfGwwlalghllaglllcitiigipy 34 ++fGw l++g++++ + ci+ i+i + FUN_000627-T1 72 LFFGWKLYVGCVFVPNVICIFGIAISF 98 79*******************999987 PP == domain 4 score: -2.0 bits; conditional E-value: 0.7 YccF 19 llaglllcitii 30 l++g+++ i+ FUN_000627-T1 175 LILGAVMIIVLS 186 555555555543 PP == domain 5 score: -3.0 bits; conditional E-value: 1.4 YccF 30 i 30 + FUN_000627-T1 226 V 226 2 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (258 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1249 (0.0488941); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2627.08 // Query: FUN_000628-T1 [L=145] Description: FUN_000628 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (145 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 428 (0.0167547); expected 510.9 (0.02) Passed bias filter: 281 (0.0110002); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1479.92 // Query: FUN_000629-T1 [L=748] Description: FUN_000629 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-248 824.0 1.3 1.1e-247 823.6 1.3 1.1 1 HSP70 Hsp70 protein 7.5e-16 58.3 0.0 2.7e-14 53.2 0.0 2.1 2 MreB_Mbl MreB/Mbl protein 6.3e-05 23.4 0.0 0.0015 18.9 0.0 2.5 2 FGGY_C FGGY family of carbohydrate kinases, C-termin 0.002 18.1 0.0 0.0051 16.8 0.0 1.6 1 TmcA_N tRNA(Met) cytidine acetyltransferase TmcA, N- 0.0031 17.3 0.6 0.021 14.6 0.1 2.4 3 Hydantoinase_A Hydantoinase/oxoprolinase ------ inclusion threshold ------ 0.055 13.5 0.1 4.2 7.3 0.0 2.5 2 BcrAD_BadFG BadF/BadG/BcrA/BcrD ATPase family 0.12 13.0 0.8 0.28 11.8 0.8 1.6 1 NNH6 NACHT N-terminal Helical domain 6 1 10.2 5.5 26 5.7 0.1 4.0 3 FtsA Cell division protein FtsA Domain annotation for each model (and alignments): >> HSP70 Hsp70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 823.6 1.3 3.4e-251 1.1e-247 1 597 [. 31 637 .. 31 639 .. 0.97 Alignments for each domain: == domain 1 score: 823.6 bits; conditional E-value: 3.4e-251 HSP70 1 viGiDLGttnscvavmeggkievianeegnrttPsvvaftkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengk 96 +iGiDLGtt+scv+v+++gk+e+ian++gnrttPs+vaf+++erl+G+aA +qa+ np++t+f++KrliGrkf+dp+v ++ +++p+++ ++ g+ FUN_000629-T1 31 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSCVAFNDTERLIGDAAMNQAALNPSHTIFDAKRLIGRKFDDPTVLSDLENWPFQIINE-FGN 125 59****************************************************************************************99.999 PP HSP70 97 alveveaage..kfspeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd.kernvl 189 ++++v+ +g fspe+is+mvL+k+ketaeaylg++v++avitvPaYfn +qRqatkdAg iAGLnv Ri+NepTAaalaYGldk+ e+nvl FUN_000629-T1 126 PKIRVQSKGSwkWFSPEEISSMVLTKMKETAEAYLGQTVKNAVITVPAYFNASQRQATKDAGMIAGLNVQRIINEPTAAALAYGLDKNLpGEKNVL 221 9999999998879**************************************************************************9889***** PP HSP70 190 vyDlGggtfdvSileleeG.vfevkaTngDthlGGedfDealvdylveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvde 284 ++DlGggtfdvS+l+++eG fev++T+gDthlGGedfD++lvd++++efk+k + d++ +++al+rl++a e+aK++LSs +t++++ ++++ + FUN_000629-T1 222 IFDLGGGTFDVSVLTIDEGsLFEVRSTAGDTHLGGEDFDNRLVDHFAAEFKRKFKTDIKGNPRALRRLRTASERAKRSLSS--NTQASIVVDSLAA 315 *******************669***********************************************************..8999999****99 PP HSP70 285 dgkdlseklsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsksvnpDeavaiGaAvqagvlsge. 378 g d+++k++Rakfeel+ dl++ +lepvekal+dakl+k+ei+e+vlvGGstRiPkvq+l++e+fg k+++k++npDeava+GaAvqa +lsg+ FUN_000629-T1 316 -GIDFHTKITRAKFEELCFDLFSSCLEPVEKALRDAKLEKSEIHEIVLVGGSTRIPKVQQLLEEFFGgKKLNKTINPDEAVAYGAAVQATILSGNr 410 .*****************************************************************99**************************96 PP HSP70 379 .eevkdllllDvtpLslgietlggvmtkliernttiptkks.qvfstaadnqtaveikvlqgerelakdnkllgkfeldgippaprGvpqieVtfd 472 + d+lllDv pLslgiet+gg+mt++iern ipt+ + + fst++dnqt ++i+v++ger+++kdn+llg+fel+gi paprGvp+ieV+fd FUN_000629-T1 411 gDGIGDILLLDVAPLSLGIETAGGIMTTVIERNSRIPTSMTrKEFSTYTDNQTGITIQVYEGERAMTKDNNLLGRFELTGISPAPRGVPKIEVSFD 506 66899**********************************9999***************************************************** PP HSP70 473 idanGiltvsakdkgtgkeeeitieaseg.lseeeiekmvkdaeesaeedkkkkeaieakneaeelvyslekkleee..kekvseaek....ekve 561 idanGil vsakd++tg+++ iti++++g ls++eie+mv dae+++e+d++++e+i a+n++e++vys++++ e+ k+k++ + +k + FUN_000629-T1 507 IDANGILAVSAKDQSTGRSNAITITNDTGrLSKDEIERMVADAEKYKEDDQEQREEIAARNSLENFVYSVKHAAEDPnlKDKLNTTDSetltSKTQ 602 *****************************9********************************************9988999999988845556666 PP HSP70 562 eaieelkeeleeedkeeieakteelkkvvekiaekl 597 e +++l+++ ++++ke++e+k ++lk+v+++i++k+ FUN_000629-T1 603 EVMDWLENN-STAEKEDYERKEKDLKEVCSPIMSKV 637 666777777.46779****************99876 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.019 60 3 35 .. 31 72 .. 29 88 .. 0.62 2 ! 53.2 0.0 8.4e-18 2.7e-14 90 316 .. 161 400 .. 141 407 .. 0.78 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.019 MreB_Mbl 3 dlgiDLGtantlv..yvkgkgivl.ne......psvvAiekk 35 +giDLGt+ v +++gk ++ n+ ps vA++ + FUN_000629-T1 31 AIGIDLGTTYSCVgvFQHGKVEIIaNDqgnrttPSCVAFNDT 72 69*******998833555554333132222223666666655 PP == domain 2 score: 53.2 bits; conditional E-value: 8.4e-18 MreB_Mbl 90 slskprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGaglpveep..sgnmvvdiGggttevavisl..ggivtsks....vrvaG 177 + ++ vi+vP ++ +r+A k+a + aG + +i+ep aAA+ gl+ + p + ++ d+Gggt +v+v+++ g++ + +s +++G FUN_000629-T1 161 GQTVKNAVITVPAYFNASQRQATKDAGMIAGLNVQRIINEPTAAALAYGLDKNLPgeKNVLIFDLGGGTFDVSVLTIdeGSLFEVRStagdTHLGG 256 34567899**************************************8888766653267899************98733566665552223689** PP MreB_Mbl 178 deldeaiikyi....rkkynlli.Ge.rtaeeikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealkepvsaiveavkevLektpp 266 +++d+ ++++ ++k++ i G+ r ++++++ a + +++ + +i l+ g+ +++++ ++ +e + +s+ +e v+++L++++ FUN_000629-T1 257 EDFDNRLVDHFaaefKRKFKTDIkGNpRALRRLRTASERAKRSLSSNtQASIVVDSLAAGIDFHTKITRAKFEELCFDLFSSCLEPVEKALRDAKL 352 ********9963333777777773331344556655555555444445999999***************************************998 PP MreB_Mbl 267 eLaadivdrgivltGGgallkgldkllseetg.lpvkvaedpltcvakGtg 316 e ++i ivl+GG++ + +++ll+e +g + + + +p ++va G++ FUN_000629-T1 353 EK-SEIH--EIVLVGGSTRIPKVQQLLEEFFGgKKLNKTINPDEAVAYGAA 400 85.5675..59******************9972467788899999999986 PP >> FGGY_C FGGY family of carbohydrate kinases, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.0 4.6e-07 0.0015 113 196 .. 299 405 .. 280 407 .. 0.76 2 ? 1.6 0.0 0.098 3.1e+02 41 75 .. 595 627 .. 593 656 .. 0.72 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 4.6e-07 FGGY_C 113 Glsssttlaelaraileglalqlrqilealeke.....................eghpidtiavvGGgskndlllqllAdalg.lpvevpqt.dea 185 lss+t+++ ++ ++ g+ + ++ ++e+ e+++i i++vGG ++ + ++qll + +g +++ + + dea FUN_000629-T1 299 SLSSNTQASIVVDSLAAGIDFHTKITRAKFEELcfdlfssclepvekalrdaklEKSEIHEIVLVGGSTRIPKVQQLLEEFFGgKKLNKTINpDEA 394 5566666666666666666666666666665556666666666666668888889****************************9777666666*** PP FGGY_C 186 talGaallaav 196 +a Gaa+ a + FUN_000629-T1 395 VAYGAAVQATI 405 *******9975 PP == domain 2 score: 1.6 bits; conditional E-value: 0.098 FGGY_C 41 eggqsaagsllawllqel.elreeladagnveesla 75 e +s+++++++wl ++ +++e+ ++++ ++l+ FUN_000629-T1 595 ETLTSKTQEVMDWLENNStAEKEDYERKE---KDLK 627 567899*********99543333333333...4443 PP >> TmcA_N tRNA(Met) cytidine acetyltransferase TmcA, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 1.6e-06 0.0051 25 94 .. 107 178 .. 95 186 .. 0.89 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.6e-06 TmcA_N 25 lvlsgdeswclellervle...kekkkgsvlyvshseledieledlsyskaeklLGqeydllvlDatdgfrpn 94 vls+ e+w +++++++++ + ++kgs+ + s++e+++ + + ++ae +LGq+++ +v+ + f+++ FUN_000629-T1 107 TVLSDLENWPFQIINEFGNpkiRVQSKGSWKWFSPEEISS-MVLTKMKETAEAYLGQTVKNAVITVPAYFNAS 178 68999999****88999889999*****************.5777778999*************998888775 PP >> Hydantoinase_A Hydantoinase/oxoprolinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.27 8.5e+02 80 106 .. 30 56 .. 24 65 .. 0.86 2 ! 14.6 0.1 6.5e-06 0.021 23 97 .. 161 236 .. 144 253 .. 0.74 3 ? -2.3 0.0 0.93 3e+03 231 252 .. 345 367 .. 264 401 .. 0.61 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.27 Hydantoinase_A 80 klIlfDmGGTstDislikdgevevete 106 ++I++D+G T + ++++++g+ve+ + FUN_000629-T1 30 PAIGIDLGTTYSCVGVFQHGKVEIIAN 56 78********************98665 PP == domain 2 score: 14.6 bits; conditional E-value: 6.5e-06 Hydantoinase_A 23 ekslekegskapvyvmqsdGglv.sieearkkpvetilSGPaaGvvgaaelsklegeeklIlfDmGGTstDislik 97 + ++++ +++p y+ +s+ +++ ++ + v+ i+ P a + ++ +l+ge+++++fD+GG ++D+s++ FUN_000629-T1 161 GQTVKNAVITVPAYFNASQRQATkDAGMIAGLNVQRIINEPTAAALAYGLDKNLPGEKNVLIFDLGGGTFDVSVLT 236 4555555555666666666554414555667778899999***999999999********************9864 PP == domain 3 score: -2.3 bits; conditional E-value: 0.93 Hydantoinase_A 231 kvtvergldpse.ltlvvfGGaG 252 k +++ +l++se + +v +GG+ FUN_000629-T1 345 KALRDAKLEKSEiHEIVLVGGST 367 33333333333313334444444 PP >> BcrAD_BadFG BadF/BadG/BcrA/BcrD ATPase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.019 60 1 47 [. 32 79 .. 32 91 .. 0.86 2 ? 7.3 0.0 0.0013 4.2 223 270 .. 356 402 .. 305 403 .. 0.80 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.019 BcrAD_BadFG 1 lGiDgGsTktkavlldeege.vlgraiagsaniesvgeeaaeknleea 47 +GiD+G+T + +++ ++ ++++ + + + + v++++ e+++ +a FUN_000629-T1 32 IGIDLGTTYSCVGVFQHGKVeIIANDQGNRTTPSCVAFNDTERLIGDA 79 7*******9999999999988999999999999999999999998887 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0013 BcrAD_BadFG 223 e...vvltGGvaknealvkalrdlvkekilevkvkvhpdpqyegaiGAaLl 270 e +vl+GG + + v ++l++e ++++k + ++ p ++a GAa+ FUN_000629-T1 356 EiheIVLVGGSTRI-PKV---QQLLEEFFGGKKLNKTINPDEAVAYGAAVQ 402 2445**********.444...44589999999****************986 PP >> NNH6 NACHT N-terminal Helical domain 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.8 8.8e-05 0.28 53 113 .. 562 623 .. 557 624 .. 0.91 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 8.8e-05 NNH6 53 a.aanaalrrlrkrlneaaeeagvplrlevtgdkkagpeeRtvwFegedlapaapatrelra 113 + aa +l++++ ++ aae+ +++ +l++t++ ++ + +v+ + e +++a+ + +e+++ FUN_000629-T1 562 EiAARNSLENFVYSVKHAAEDPNLKDKLNTTDSETLTSKTQEVMDWLENNSTAEKEDYERKE 623 34999**************************************9999999999999999887 PP >> FtsA Cell division protein FtsA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.1 0.0081 26 2 24 .. 33 52 .. 32 178 .. 0.90 2 ? 3.4 0.1 0.041 1.3e+02 4 104 .. 224 381 .. 221 398 .. 0.50 3 ? 0.9 0.2 0.24 7.8e+02 33 94 .. 530 571 .. 517 649 .. 0.72 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0081 xxxxxxxxxxxxxxxxxxxxxxx RF FtsA 2 liDiGggttdiavfedgalrhte 24 +iD+G++ ++ vf++g++ e FUN_000629-T1 33 GIDLGTTYSCVGVFQHGKV---E 52 8***************954...3 PP == domain 2 score: 3.4 bits; conditional E-value: 0.041 xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxx......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 4 DiGggttdiavfedgalrhtevipv......ggngitkd......................iakglrtaveeAErlkikyGsalaseadeeeeevp 71 D+Gggt d++v ++ ev gg+ + + + + lrta e A+r FUN_000629-T1 224 DLGGGTFDVSVLTIDEGSLFEVRSTagdthlGGEDFDNRlvdhfaaefkrkfktdikgnprALRRLRTASERAKRSL------------------- 300 77777777777654332222222222233446666666644444444444444444443333333344444444333................... PP xxxxxxxxxxxxxxxx..........................................................xxxxxxxxxxxxxxxxx RF FtsA 72 gvggrepreisrkela..........................................................ggsalkglkelaeralg 104 s ++ a g++ ++++++l+e+ +g FUN_000629-T1 301 ----------SSNTQAsivvdslaagidfhtkitrakfeelcfdlfssclepvekalrdaklekseiheivlvgGSTRIPKVQQLLEEFFG 381 ..........211111222222223444444444444446777777777777777777777777777788888888889999999988883 PP == domain 3 score: 0.9 bits; conditional E-value: 0.24 xxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 33 itkd....iakglrtaveeAErlkikyGsalaseadeeeeevpgvggrepreisrkelaggsalkg 94 it+d + + v++AE+ k +d++e +r+e+a ++l++ FUN_000629-T1 530 ITNDtgrlSKDEIERMVADAEKYK----------EDDQE--------------QREEIAARNSLEN 571 666655544455677778888888..........22222..............3334444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (748 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1586 (0.0620865); expected 510.9 (0.02) Passed bias filter: 611 (0.0239186); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 7126.12 // Query: FUN_000630-T1 [L=259] Description: FUN_000630 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-11 43.3 10.4 9.9e-11 42.3 10.4 1.4 1 CECR6_TMEM121 CECR6/TMEM121 family Domain annotation for each model (and alignments): >> CECR6_TMEM121 CECR6/TMEM121 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.3 10.4 3.9e-15 9.9e-11 5 191 .. 75 252 .. 72 254 .. 0.86 Alignments for each domain: == domain 1 score: 42.3 bits; conditional E-value: 3.9e-15 CECR6_TMEM121 5 laWllYv.ivlvikvvlifknsiadelkeldvfgkkllkvllslsvpllflllvaihhaeeprskrklylkslllsvvldLlDslelleiLlekes 99 + W lYv v+v+ v+ if +++ ++++ + ++l+++++ + p+l lll + ++ +++++ +++l + +v dL+D +ell+ l+ +s FUN_000630-T1 75 FWWKLYVgCVFVPNVICIFGIAFSF-EEDKLPYSVNGLTLTVCAT-PILLLLLLITADDSFSSKNHRDLVRNLSILMVSDLIDGIELLDSTLKGNS 168 67****746799*********9888.4455559************.99999988888888888899999*************************97 PP CECR6_TMEM121 100 tnLplkleglvlvvacinlflPvlaLyelsvskvsqkvkivslkklyallslllvnvpllviRlllffrdnrdvsifllKNvlailikllei 191 + +++++ a++ ++l + ++e++ + + ++++ + + + ++++++n ++l++R+ + + + ++KN +ai++ ++ei FUN_000630-T1 169 YG---IHKSFLILGAVMIIVLSSFQMAEYKFVGGELMEQPIYTTTVIRHIFVIILNLVFLIVRVKV-----SRPILIIFKNCMAIVLSVIEI 252 55...2345555566666799**********9999999*************************744.....55668899*********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (259 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1211 (0.0474065); expected 510.9 (0.02) Passed bias filter: 343 (0.0134273); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2593.32 // Query: FUN_000631-T1 [L=78] Description: FUN_000631 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (78 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 443 (0.0173419); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 798.75 // Query: FUN_000632-T1 [L=619] Description: FUN_000632 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-255 850.1 6.0 1.2e-255 849.9 6.0 1.0 1 HSP70 Hsp70 protein 5.2e-18 65.5 0.0 2.3e-16 60.0 0.0 2.2 2 MreB_Mbl MreB/Mbl protein 3.4e-06 27.6 0.0 0.00015 22.2 0.0 2.5 2 FGGY_C FGGY family of carbohydrate kinases, C-termin 0.0015 18.4 0.9 0.011 15.5 0.1 2.5 3 Hydantoinase_A Hydantoinase/oxoprolinase 0.0043 17.0 4.6 0.0093 15.9 4.6 1.5 1 Radial_spoke_3 Radial spoke protein 3 ------ inclusion threshold ------ 0.011 15.8 0.0 1.7 8.6 0.0 2.5 2 BcrAD_BadFG BadF/BadG/BcrA/BcrD ATPase family 0.046 13.7 0.0 0.13 12.2 0.0 1.7 1 TmcA_N tRNA(Met) cytidine acetyltransferase TmcA, N- 0.06 14.2 5.9 6 7.7 0.1 3.8 3 FtsA Cell division protein FtsA Domain annotation for each model (and alignments): >> HSP70 Hsp70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 849.9 6.0 3.8e-259 1.2e-255 1 596 [. 8 612 .. 8 615 .. 0.97 Alignments for each domain: == domain 1 score: 849.9 bits; conditional E-value: 3.8e-259 HSP70 1 viGiDLGttnscvavmeggkievianeegnrttPsvvaftkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengk 96 +iGiDLGtt+scv+v+++gk+e+ian++gnrttPs+vaf+++erl+G+aAk+qa+ np++t+f++KrliGrkf+dp+vq++ k+++++v ++ gk FUN_000632-T1 8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFNDTERLIGDAAKNQAALNPSHTIFDAKRLIGRKFDDPTVQSDRKNWSFQVINE-YGK 102 59****************************************************************************************99.9** PP HSP70 97 alveveaage..kfspeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd.kernvl 189 ++++v+ +g+ +fspeqis+mvL+k+ketaeaylg++v++avitvPaYfnd+qRqatkdAg iAGLnv Ri+NepTAaalaYGldk+ e+nvl FUN_000632-T1 103 PKIRVQSKGDwkTFSPEQISSMVLTKMKETAEAYLGQTVKNAVITVPAYFNDSQRQATKDAGMIAGLNVQRIINEPTAAALAYGLDKNLqGEKNVL 198 *******99999***************************************************************************9658***** PP HSP70 190 vyDlGggtfdvSileleeG.vfevkaTngDthlGGedfDealvdylveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvde 284 ++DlGggtfdvS+l+++eG fev++T+gDthlGGedfD++lvd++++efk+k + d++ +++al+rl++a e+aK++LSs +t++++e++++ e FUN_000632-T1 199 IFDLGGGTFDVSVLTIDEGsLFEVRSTAGDTHLGGEDFDNRLVDHFAAEFKRKFKTDIKGNPRALRRLRTASERAKRSLSS--STQASIEVDSLAE 292 *******************669***********************************************************..99**********9 PP HSP70 285 dgkdlseklsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsksvnpDeavaiGaAvqagvlsge. 378 g d+++k++Rakfeel++dl++ +lepvekal+dakl+k+ei+e+vlvGGstRiP+vq+l++e+fg k+++k++npDeava+GaAvqa++lsg+ FUN_000632-T1 293 -GIDFHTKITRAKFEELCHDLFSSCLEPVEKALRDAKLEKSEIHEIVLVGGSTRIPNVQKLLEEFFGgKKLNKTINPDEAVAYGAAVQAAILSGDq 387 .*****************************************************************99**************************97 PP HSP70 379 .eevkdllllDvtpLslgietlggvmtkliernttiptkksqvfstaadnqtaveikvlqgerelakdnkllgkfeldgippaprGvpqieVtfdi 473 evkd+lllDv pLslgiet+gg+mt+liern iptk s+ f+t+a+nq+av+i++++ger+++kdn+llg+fel+gippaprGvp+ieV+fdi FUN_000632-T1 388 sAEVKDVLLLDVAPLSLGIETAGGMMTTLIERNSRIPTKTSKEFTTFANNQPAVTIQIYEGERAMTKDNNLLGRFELTGIPPAPRGVPKIEVSFDI 483 779********************************************************************************************* PP HSP70 474 danGiltvsakdkgtgkeeeitieaseg.lseeeiekmvkdaeesaeedkkkkeaieakneaeelvyslekkleee..kekvseaek....ekvee 562 danGil+vsakd++tg+++ iti++++g ls++ei++mv dae+++e+d++++e+i a+n++e++vys++++ e+ k k++ + +k +e FUN_000632-T1 484 DANGILNVSAKDQSTGRSNAITITNDTGrLSKAEIDRMVADAEKYKEDDQRQREKIAARNSLENYVYSVKEAAEDPhlKGKLNTTDLetvtSKTRE 579 ****************************9********************************************99888888988888444455555 PP HSP70 563 aieelkeeleeedkeeieakteelkkvvekiaek 596 +++l+++ ++++ke++e+k ++l++v+++i++k FUN_000632-T1 580 VMDWLENN-STAEKEDYESKEKDLQQVCSPIMAK 612 66666666.46679****************9987 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.015 47 3 35 .. 8 49 .. 6 67 .. 0.58 2 ! 60.0 0.0 7.3e-20 2.3e-16 90 316 .. 138 377 .. 117 385 .. 0.78 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.015 MreB_Mbl 3 dlgiDLGtantlv..yvkgkgivl.ne......psvvAiekk 35 +giDLGt+ v +++gk ++ n+ ps vA++ + FUN_000632-T1 8 AIGIDLGTTYSCVgvFQHGKVEIIaNDqgnrttPSYVAFNDT 49 69*******999833555554333121222222555555544 PP == domain 2 score: 60.0 bits; conditional E-value: 7.3e-20 MreB_Mbl 90 slskprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGagl..pveepsgnmvvdiGggttevavisl..ggivtsks....vrvaG 177 + ++ vi+vP ++ +r+A k+a + aG + +i+ep aAA+ gl +++ + ++ d+Gggt +v+v+++ g++ + +s +++G FUN_000632-T1 138 GQTVKNAVITVPAYFNDSQRQATKDAGMIAGLNVQRIINEPTAAALAYGLdkNLQGEKNVLIFDLGGGTFDVSVLTIdeGSLFEVRStagdTHLGG 233 34567899************************************9966662268889999**************98733566665552223689** PP MreB_Mbl 178 deldeaiikyi....rkkynlli.Ge.rtaeeikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealkepvsaiveavkevLektpp 266 +++d+ ++++ ++k++ i G+ r ++++++ a + +++ + +i+ l++g+ +++++ ++ +e ++ +s+ +e v+++L++++ FUN_000632-T1 234 EDFDNRLVDHFaaefKRKFKTDIkGNpRALRRLRTASERAKRSLSSStQASIEVDSLAEGIDFHTKITRAKFEELCHDLFSSCLEPVEKALRDAKL 329 ********9963333777777773331334555555555554444446899999***************************************998 PP MreB_Mbl 267 eLaadivdrgivltGGgallkgldkllseetg.lpvkvaedpltcvakGtg 316 e ++i ivl+GG++ + +++kll+e +g + + + +p ++va G++ FUN_000632-T1 330 EK-SEIH--EIVLVGGSTRIPNVQKLLEEFFGgKKLNKTINPDEAVAYGAA 377 85.5675..59******************9972467788899999999986 PP >> FGGY_C FGGY family of carbohydrate kinases, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.0 4.6e-08 0.00015 112 196 .. 275 382 .. 255 384 .. 0.88 2 ? 2.5 0.0 0.051 1.6e+02 40 75 .. 570 603 .. 562 617 .. 0.67 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 4.6e-08 FGGY_C 112 iGlsssttlaelaraileglalqlrqilealeke.....................eghpidtiavvGGgskndlllqllAdalg.lpvevpqt.de 184 + lssst+++ ++ ++ eg+ + ++ ++e+ e+++i i++vGG ++ + +++ll + +g +++ + + de FUN_000632-T1 275 RSLSSSTQASIEVDSLAEGIDFHTKITRAKFEELchdlfssclepvekalrdaklEKSEIHEIVLVGGSTRIPNVQKLLEEFFGgKKLNKTINpDE 370 7899999999**************9999999888999999999999999999999*****************************9777666666** PP FGGY_C 185 atalGaallaav 196 a+a Gaa+ aa+ FUN_000632-T1 371 AVAYGAAVQAAI 382 **********97 PP == domain 2 score: 2.5 bits; conditional E-value: 0.051 FGGY_C 40 leggqsaagsllawllqel.elreeladagnveesla 75 le +s+++++++wl ++ +++e+ ++++ ++l+ FUN_000632-T1 570 LETVTSKTREVMDWLENNStAEKEDYESKE---KDLQ 603 678899**********99433333333322...3333 PP >> Hydantoinase_A Hydantoinase/oxoprolinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.21 6.6e+02 80 106 .. 7 33 .. 3 45 .. 0.85 2 ! 15.5 0.1 3.4e-06 0.011 22 97 .. 137 213 .. 120 230 .. 0.75 3 ? -1.6 0.0 0.56 1.8e+03 216 267 .. 311 361 .. 241 380 .. 0.58 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.21 Hydantoinase_A 80 klIlfDmGGTstDislikdgevevete 106 ++I++D+G T + ++++++g+ve+ + FUN_000632-T1 7 PAIGIDLGTTYSCVGVFQHGKVEIIAN 33 68********************98765 PP == domain 2 score: 15.5 bits; conditional E-value: 3.4e-06 Hydantoinase_A 22 vekslekegskapvyvmqsdGglv.sieearkkpvetilSGPaaGvvgaaelsklegeeklIlfDmGGTstDislik 97 + + ++++ +++p y+ +s+ +++ ++ + v+ i+ P a + ++ +l+ge+++++fD+GG ++D+s++ FUN_000632-T1 137 LGQTVKNAVITVPAYFNDSQRQATkDAGMIAGLNVQRIINEPTAAALAYGLDKNLQGEKNVLIFDLGGGTFDVSVLT 213 55556666666777777776655424556677778999999****99999999********************9864 PP == domain 3 score: -1.6 bits; conditional E-value: 0.56 Hydantoinase_A 216 giirianeemaeavrkvtvergldpse.ltlvvfGGaG..pqhaaalaeelgikk 267 + + e +++a+r+ +l++se + +v +GG+ p + ++l+e +g kk FUN_000632-T1 311 DLFSSCLEPVEKALRDA----KLEKSEiHEIVLVGGSTriPNVQKLLEEFFGGKK 361 44444444444444444....3333331344445555433444455555555555 PP >> Radial_spoke_3 Radial spoke protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 4.6 2.9e-06 0.0093 126 225 .. 514 615 .. 505 616 .. 0.82 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.9e-06 Radial_spoke_3 126 lkeekerrlkqqkealekeketeekiaaralakqylsellksvlesLedkgyfydpver..eveeeflpwLmeevekelekkkearelldsiiee 218 k+e +r +++ ++ +e ++ +ekiaar+ ++y+ ++++ + + + + ++++e+ + ++e ++wL ++ ++e e+ ++ ++ l+++++ FUN_000632-T1 514 SKAEIDRMVADAEKYKEDDQRQREKIAARNSLENYVYSVKEAAEDPHLKGKLNTTDLETvtSKTREVMDWLENNSTAEKEDYESKEKDLQQVCSP 608 4678999999999999999*******************9999887544444444445541145679****************************9 PP Radial_spoke_3 219 vvekrle 225 ++ k+++ FUN_000632-T1 609 IMAKQQS 615 9988875 PP >> BcrAD_BadFG BadF/BadG/BcrA/BcrD ATPase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.008 25 1 49 [. 9 58 .. 9 68 .. 0.88 2 ? 8.6 0.0 0.00053 1.7 217 270 .. 327 379 .. 266 380 .. 0.75 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.008 BcrAD_BadFG 1 lGiDgGsTktkavlldeege.vlgraiagsaniesvgeeaaeknleeaie 49 +GiD+G+T + +++ ++ ++++ + + + + v++++ e+++ +a + FUN_000632-T1 9 IGIDLGTTYSCVGVFQHGKVeIIANDQGNRTTPSYVAFNDTERLIGDAAK 58 7*******999999999998899999999999999999999999999865 PP == domain 2 score: 8.6 bits; conditional E-value: 0.00053 BcrAD_BadFG 217 lgevkde...vvltGGvaknealvkalrdlvkekilevkvkvhpdpqyegaiGAaLl 270 + +k e +vl+GG + ++ +l++e ++++k + ++ p ++a GAa+ FUN_000632-T1 327 AKLEKSEiheIVLVGGSTRIPNVQ----KLLEEFFGGKKLNKTINPDEAVAYGAAVQ 379 3333333566**********4444....4468888888****************986 PP >> TmcA_N tRNA(Met) cytidine acetyltransferase TmcA, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 4e-05 0.13 27 91 .. 86 152 .. 75 157 .. 0.87 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 4e-05 TmcA_N 27 lsgdeswclellervle...kekkkgsvlyvshseledieledlsyskaeklLGqeydllvlDatdgf 91 s+ ++w++++++++++ + ++kg++ s++++++ + + ++ae +LGq+++ +v+ + f FUN_000632-T1 86 QSDRKNWSFQVINEYGKpkiRVQSKGDWKTFSPEQISS-MVLTKMKETAEAYLGQTVKNAVITVPAYF 152 567789****889999999999****************.5777778999************9876555 PP >> FtsA Cell division protein FtsA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.2 0.005 16 2 25 .. 10 30 .. 9 160 .. 0.75 2 ? 7.7 0.1 0.0019 6 4 125 .. 201 373 .. 198 375 .. 0.61 3 ? 0.1 0.2 0.43 1.4e+03 33 86 .. 506 539 .. 493 593 .. 0.64 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.005 xxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 2 liDiGggttdiavfedgalrhtev 25 +iD+G++ ++ vf++g++ + FUN_000632-T1 10 GIDLGTTYSCVGVFQHGKVE---I 30 8***************9654...3 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0019 xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxx......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 4 DiGggttdiavfedgalrhtevipv......ggngitkd......................iakglrtaveeAErlkikyGsalaseadeeeeevp 71 D+Gggt d++v ++ ev gg+ + + + + lrta e A+r ++s + + e++ FUN_000632-T1 201 DLGGGTFDVSVLTIDEGSLFEVRSTagdthlGGEDFDNRlvdhfaaefkrkfktdikgnprALRRLRTASERAKRSL------SSSTQASIEVDSL 290 78888888877665433333333332244457777777766666666666666666666665666666666666666......1111111111222 PP xxxxxxxxxxxxxxxx...................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 72 gvggrepreisrkela...................................ggsalkglkelaeralglpvrigspkleevrnPeyata 125 +g + +i+r++ + g++ ++++++l+e+ +g kl++ nP a+a FUN_000632-T1 291 AEGIDFHTKITRAKFEelchdlfssclepvekalrdaklekseiheivlvgGSTRIPNVQKLLEEFFGG------KKLNKTINPDEAVA 373 222233333333333377899999999999999999999999999*********************933......22444556665555 PP == domain 3 score: 0.1 bits; conditional E-value: 0.43 xxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 33 itkd....iakglrtaveeAErlkikyGsalaseadeeeeevpgvggrepreisrkel 86 it+d + v++AE+ k ++++r++ +++ FUN_000632-T1 506 ITNDtgrlSKAEIDRMVADAEKYK-------------------EDDQRQR-----EKI 539 666655532334677788888888...................1222222.....222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (619 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1267 (0.0495987); expected 510.9 (0.02) Passed bias filter: 706 (0.0276375); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.40u 0.38s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 5966.20 // Query: FUN_000633-T1 [L=112] Description: FUN_000633 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0043 17.8 0.0 0.0063 17.3 0.0 1.2 1 KH_11 Eukaryotic type KH-domain (KH-domain type I) Domain annotation for each model (and alignments): >> KH_11 Eukaryotic type KH-domain (KH-domain type I) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 2.5e-07 0.0063 13 55 .. 46 88 .. 43 94 .. 0.89 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.5e-07 KH_11 13 apggaaahArnltrYLrqrkeierLeklynarIvtpssedgal 55 a + + hA ++ r rqr+e ++++ +n I+ p se g+l FUN_000633-T1 46 ARQTMQFHADHIVRHTRQRHERLEMQESFNLAITPPASERGQL 88 5567789******************************999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (112 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1117 (0.0437268); expected 510.9 (0.02) Passed bias filter: 827 (0.0323742); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1128.44 // Query: FUN_000634-T1 [L=316] Description: FUN_000634 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0095 16.7 0.3 0.25 12.2 0.0 2.3 2 LuxT_C Tetracycline repressor LuxT C-terminal domain ------ inclusion threshold ------ 4.5 6.4 4.5 6.4 5.9 4.5 1.1 1 Presenilin Presenilin Domain annotation for each model (and alignments): >> LuxT_C Tetracycline repressor LuxT C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.3 0.034 4.3e+02 13 31 .. 42 60 .. 38 63 .. 0.91 2 ! 12.2 0.0 1.9e-05 0.25 13 78 .. 175 238 .. 173 241 .. 0.86 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.034 LuxT_C 13 dfSsaealeesweealkqp 31 ++Ss++ +++s +a+ ++ FUN_000634-T1 42 NLSSMQSFASSHGNAMDKN 60 79*************9986 PP == domain 2 score: 12.2 bits; conditional E-value: 1.9e-05 LuxT_C 13 dfSsaealeesweealkqpkfkavlklffslcgsqqeeektkralndlrekaveklgdegeetles 78 ++Ss +++s ea+ ++ + ++ ++g+ ++ nd++e +ve+lgd g+ t++s FUN_000634-T1 175 NLSSTRSFASSHGEAIDKNGWSILFSFLRASSGH--SFLFIASPCNDAKECVVERLGDIGKTTVNS 238 79***************99998877776655554..567888899******************986 PP >> Presenilin Presenilin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 4.5 0.0005 6.4 234 318 .. 65 149 .. 36 170 .. 0.34 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0005 Presenilin 234 eeaeeeeeaekkkeeeeeeskkeeseeeeseksassseeeeseeteeeesaeeeseeeseeesseaessteesseekekeeseee 318 + ++++ +e +k++ ee+s+k + e e+ +++++++++ ++ +++ +++++ + ++++ e e+++++s++eke+ +e+ FUN_000634-T1 65 KAGKKRDFREGNKRRREETSEKVTIEGERRLQRNQQRKKPGQHILLHRHMGMQRTRMDGRRRQGERERRPQKSQQEKERGDYKEA 149 1122222222222222222222222222222222222222222222222222222222222222222222222222221111111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (316 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1135 (0.0444314); expected 510.9 (0.02) Passed bias filter: 530 (0.0207477); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3046.36 // Query: FUN_000635-T1 [L=250] Description: FUN_000635 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0012 19.3 12.3 0.023 15.3 3.5 2.6 2 zf-CCHC Zinc knuckle ------ inclusion threshold ------ 0.039 14.3 0.0 0.092 13.1 0.0 1.6 2 RRM_1 RNA recognition motif Domain annotation for each model (and alignments): >> zf-CCHC Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 1.6 0.00019 2.4 2 17 .. 189 204 .. 188 205 .. 0.92 2 ! 15.3 3.5 1.8e-06 0.023 3 18 .] 209 224 .. 207 224 .. 0.91 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00019 zf-CCHC 2 kCynCGepGHiardCp 17 +C C e+GH a Cp FUN_000635-T1 189 QCSICREVGHCAPACP 204 7***********9998 PP == domain 2 score: 15.3 bits; conditional E-value: 1.8e-06 zf-CCHC 3 CynCGepGHiardCpk 18 C+ C +pGH+a++C++ FUN_000635-T1 209 CRCCRQPGHVASQCTQ 224 999***********97 PP >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 1.1 1.4e+04 45 65 .. 81 99 .. 76 100 .. 0.73 2 ? 13.1 0.0 7.2e-06 0.092 1 29 [. 115 143 .. 115 149 .. 0.93 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 1.1 RRM_1 45 eFedeedaekAlealngkelg 65 +F+d+e + l+ ng e++ FUN_000635-T1 81 TFDDPEVCSAVLR--NGLEFE 99 7888888888887..777765 PP == domain 2 score: 13.1 bits; conditional E-value: 7.2e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksir 29 +++++Lp +v+++ ++ +Fs +G++ s++ FUN_000635-T1 115 VYLRDLPVEVDNDVVSSFFSRYGEVLSVD 143 799**********************9997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (250 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 844 (0.0330397); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2440.17 // Query: FUN_000636-T1 [L=140] Description: FUN_000636 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-05 23.6 0.0 6.3e-05 23.5 0.0 1.1 1 Acetyltransf_10 Acetyltransferase (GNAT) domain 0.0014 19.5 0.0 0.0023 18.7 0.0 1.3 1 Acetyltransf_7 Acetyltransferase (GNAT) domain 0.0016 19.2 0.0 0.0035 18.1 0.0 1.3 1 Acetyltransf_1 Acetyltransferase (GNAT) family ------ inclusion threshold ------ 0.12 12.7 0.3 9.4 6.6 0.1 2.6 2 Ble-like_N Bleomycin resistance protein-like N-terminal Domain annotation for each model (and alignments): >> Acetyltransf_10 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 9.9e-09 6.3e-05 38 109 .. 46 123 .. 20 136 .. 0.81 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 9.9e-09 Acetyltransf_10 38 edgeivGviel.rdns..hlsllfVdkey.qgqGiakaLlkaveeeaekddiel.eltvnssp.tavpfYeklGFvat 109 + ++ +Gv ++ + ++ l++l + ++ + G++k+Ll+ v+++++ +d + + ++ + av+fY klGF ++ FUN_000636-T1 46 WRKKPAGVYRTlESQRslVLDMLLLSLAFmKDLGMGKRLLACVLSALKAEDCKGvHCEIPTTSsGAVDFYTKLGFYKI 123 467899999885444478999999999873678*************8888887778888766559**********887 PP >> Acetyltransf_7 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 3.6e-07 0.0023 44 83 .. 79 121 .. 75 122 .. 0.66 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 3.6e-07 Acetyltransf_7 44 GiGraLleaa.eaaa..kekgikll..elannneaarfYeklGFe 83 G G++Ll+ + a++ +kg++ + + +++ a+ fY klGF FUN_000636-T1 79 GMGKRLLACVlSALKaeDCKGVHCEipT--TSSGAVDFYTKLGFY 121 99*****988633333444454333333..3448999*******6 PP >> Acetyltransf_1 Acetyltransferase (GNAT) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.0 5.5e-07 0.0035 74 116 .] 78 120 .. 70 120 .. 0.95 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 5.5e-07 Acetyltransf_1 74 kGiGtaLlealleyarergcerlyleveedNeaaialYeklGF 116 G G++Ll+ +l +++++c+ +++e+ ++ +a+++Y+klGF FUN_000636-T1 78 LGMGKRLLACVLSALKAEDCKGVHCEIPTTSSGAVDFYTKLGF 120 699***************************************9 PP >> Ble-like_N Bleomycin resistance protein-like N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.1 0.0015 9.4 6 20 .. 16 30 .. 14 31 .. 0.91 2 ? 3.5 0.0 0.013 84 15 26 .. 111 121 .. 109 130 .. 0.78 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0015 Ble-like_N 6 elpvdDlerSkaFYq 20 l+v+D+ r+ +F++ FUN_000636-T1 16 VLFVADGLRADKFFK 30 69***********97 PP == domain 2 score: 3.5 bits; conditional E-value: 0.013 Ble-like_N 15 SkaFYqdvLGfk 26 ++ FY+ LGf FUN_000636-T1 111 AVDFYTK-LGFY 121 5679988.**95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (140 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 393 (0.0153846); expected 510.9 (0.02) Passed bias filter: 356 (0.0139362); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1401.83 // Query: FUN_000637-T1 [L=633] Description: FUN_000637 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-257 855.6 6.5 2.5e-257 855.4 6.5 1.0 1 HSP70 Hsp70 protein 1.7e-17 63.7 0.1 1.2e-15 57.6 0.0 2.2 2 MreB_Mbl MreB/Mbl protein 5.7e-06 26.8 0.0 0.00036 21.0 0.0 2.5 2 FGGY_C FGGY family of carbohydrate kinases, C-termin 0.0012 18.7 0.7 0.011 15.5 0.1 2.6 3 Hydantoinase_A Hydantoinase/oxoprolinase 0.0063 16.4 3.5 0.013 15.4 3.5 1.5 1 Radial_spoke_3 Radial spoke protein 3 ------ inclusion threshold ------ 0.015 15.4 0.0 1.8 8.5 0.0 2.4 2 BcrAD_BadFG BadF/BadG/BcrA/BcrD ATPase family 0.15 13.0 5.4 12 6.8 0.1 3.8 3 FtsA Cell division protein FtsA Domain annotation for each model (and alignments): >> HSP70 Hsp70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 855.4 6.5 6.8e-261 2.5e-257 1 597 [. 8 613 .. 8 615 .. 0.96 Alignments for each domain: == domain 1 score: 855.4 bits; conditional E-value: 6.8e-261 HSP70 1 viGiDLGttnscvavmeggkievianeegnrttPsvvaftkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengk 96 +iGiDLGtt+scv+v+++gk+e+ian++gnrttPs+vaf+++erl+GeaAk+qa+ np++t+f++KrliGrkf+dp+vq++ k++p++vv++ gk FUN_000637-T1 8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFNETERLIGEAAKNQAALNPSHTIFDAKRLIGRKFDDPTVQSDRKNWPFQVVNE-SGK 102 59****************************************************************************************99.899 PP HSP70 97 alveveaage..kfspeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd.kernvl 189 ++++v+ +++ +fspeqis+mvL+k+ketaeaylg++v++avitvPaYfnd+qRqatkdAg iAGLnv Ri+NepTAaalaYGldk+ e+nvl FUN_000637-T1 103 PKIRVQSKKDwkTFSPEQISSMVLTKMKETAEAYLGQTVKNAVITVPAYFNDSQRQATKDAGMIAGLNVQRIINEPTAAALAYGLDKNLqGEKNVL 198 999999877677***************************************************************************9658***** PP HSP70 190 vyDlGggtfdvSileleeG.vfevkaTngDthlGGedfDealvdylveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvde 284 ++DlGggtfdvS+l+++eG fev++T+gDthlGGedfD++lvd++++efk+k + d++ +++al+rl++a e+aK++LSs +t++++e++++ e FUN_000637-T1 199 IFDLGGGTFDVSVLTIDEGsLFEVRSTAGDTHLGGEDFDNRLVDHFAAEFKRKLKTDIKGNPRALRRLRTASERAKRSLSS--STQASIEVDSLAE 292 *******************669***********************************************************..99**********9 PP HSP70 285 dgkdlseklsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsksvnpDeavaiGaAvqagvlsge. 378 g d+++k++Rakfeel++dl++ +lepvekal+dakl+k+ei+e+vlvGGstRiPkvq+l++e+fg k+++k++npDeava+GaAvqa++lsg+ FUN_000637-T1 293 -GIDFHTKITRAKFEELCHDLFSSCLEPVEKALRDAKLEKSEIHEIVLVGGSTRIPKVQKLLEEFFGgKKLNKTINPDEAVAYGAAVQAAILSGDq 387 .*****************************************************************99**************************97 PP HSP70 379 .eevkdllllDvtpLslgietlggvmtkliernttiptkksqvfstaadnqtaveikvlqgerelakdnkllgkfeldgippaprGvpqieVtfdi 473 evkd+lllDv pLslgiet+gg+mt+liern iptk s+ f+t+adnq+av+i+v++ger+++kdn+llg+fel+gippaprGvp+ieV+fdi FUN_000637-T1 388 sAEVKDVLLLDVAPLSLGIETAGGMMTTLIERNSRIPTKTSKEFTTFADNQPAVTIQVYEGERAMTKDNNLLGRFELTGIPPAPRGVPKIEVSFDI 483 779********************************************************************************************* PP HSP70 474 danGiltvsakdkgtgkeeeitieaseg.lseeeiekmvkdaeesaeedkkkkeaieakneaeelvyslekkleee..kekvseaek....ekvee 562 danGil+vsakd++tg+++ iti+++ g ls++ei++mv dae+++e+d++++e++ a+n++e++vys++++ e+ k k++ + +k +e FUN_000637-T1 484 DANGILNVSAKDQSTGRSNAITITNDMGrLSKAEIDRMVADAEKYKEDDQRQREKVAARNSLENYVYSVKQAAEDPdlKGKLNTTDLetvtSKTRE 579 *************************9999********************************************99888889988888444455555 PP HSP70 563 aieelkeeleeedkeeieakteelkkvvekiaekl 597 +++l+++ ++++ke++e+k ++l++v+++i++k+ FUN_000637-T1 580 VMDWLENN-SAAEKEDYERKEKDLQQVCSPIMAKA 613 66666666.46679****************99875 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.8 0.0 0.0081 29 3 37 .. 8 51 .. 6 68 .. 0.55 2 ! 57.6 0.0 3.4e-19 1.2e-15 90 316 .. 138 377 .. 117 385 .. 0.77 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0081 MreB_Mbl 3 dlgiDLGtantlv..yvkgkgivl.ne......psvvAiekktk 37 +giDLGt+ v +++gk ++ n+ ps vA++++++ FUN_000637-T1 8 AIGIDLGTTYSCVgvFQHGKVEIIaNDqgnrttPSYVAFNETER 51 69*******99983345555433312122222255555555443 PP == domain 2 score: 57.6 bits; conditional E-value: 3.4e-19 MreB_Mbl 90 slskprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGagl..pveepsgnmvvdiGggttevavisl..ggivtsks....vrvaG 177 + ++ vi+vP ++ +r+A k+a + aG + +i+ep aAA+ gl +++ + ++ d+Gggt +v+v+++ g++ + +s +++G FUN_000637-T1 138 GQTVKNAVITVPAYFNDSQRQATKDAGMIAGLNVQRIINEPTAAALAYGLdkNLQGEKNVLIFDLGGGTFDVSVLTIdeGSLFEVRStagdTHLGG 233 34567899************************************9966662268889999**************98733566665552223689** PP MreB_Mbl 178 deldeaiikyirkkynlli.....Ge.rtaeeikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealkepvsaiveavkevLektpp 266 +++d+ ++++ +++ + G+ r ++++++ a + +++ + +i+ l++g+ +++++ ++ +e ++ +s+ +e v+++L++++ FUN_000637-T1 234 EDFDNRLVDHFAAEFKRKLktdikGNpRALRRLRTASERAKRSLSSStQASIEVDSLAEGIDFHTKITRAKFEELCHDLFSSCLEPVEKALRDAKL 329 **********98888655411112221233444444444443333336899999***************************************998 PP MreB_Mbl 267 eLaadivdrgivltGGgallkgldkllseetg.lpvkvaedpltcvakGtg 316 e ++i ivl+GG++ + ++kll+e +g + + + +p ++va G++ FUN_000637-T1 330 EK-SEIH--EIVLVGGSTRIPKVQKLLEEFFGgKKLNKTINPDEAVAYGAA 377 85.5675..59******************9972467788899999999986 PP >> FGGY_C FGGY family of carbohydrate kinases, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 9.8e-08 0.00036 112 196 .. 275 382 .. 256 384 .. 0.88 2 ? 3.1 0.0 0.03 1.1e+02 40 71 .. 570 606 .. 556 622 .. 0.71 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 9.8e-08 FGGY_C 112 iGlsssttlaelaraileglalqlrqilealeke.....................eghpidtiavvGGgskndlllqllAdalg.lpvevpqt.de 184 + lssst+++ ++ ++ eg+ + ++ ++e+ e+++i i++vGG ++ + +++ll + +g +++ + + de FUN_000637-T1 275 RSLSSSTQASIEVDSLAEGIDFHTKITRAKFEELchdlfssclepvekalrdaklEKSEIHEIVLVGGSTRIPKVQKLLEEFFGgKKLNKTINpDE 370 7899999999**************9999999888999999999999999999999*****************************9777666666** PP FGGY_C 185 atalGaallaav 196 a+a Gaa+ aa+ FUN_000637-T1 371 AVAYGAAVQAAI 382 **********97 PP == domain 2 score: 3.1 bits; conditional E-value: 0.03 FGGY_C 40 leggqsaagsllawllqel.elreeladagnv....e 71 le +s+++++++wl ++ +++e+ ++++++ + FUN_000637-T1 570 LETVTSKTREVMDWLENNSaAEKEDYERKEKDlqqvC 606 688899**********995433333333333344443 PP >> Hydantoinase_A Hydantoinase/oxoprolinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.18 6.7e+02 80 106 .. 7 33 .. 3 46 .. 0.85 2 ! 15.5 0.1 3e-06 0.011 22 97 .. 137 213 .. 120 231 .. 0.75 3 ? -2.0 0.0 0.63 2.3e+03 220 270 .. 315 364 .. 265 379 .. 0.55 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.18 Hydantoinase_A 80 klIlfDmGGTstDislikdgevevete 106 ++I++D+G T + ++++++g+ve+ + FUN_000637-T1 7 PAIGIDLGTTYSCVGVFQHGKVEIIAN 33 68********************98765 PP == domain 2 score: 15.5 bits; conditional E-value: 3e-06 Hydantoinase_A 22 vekslekegskapvyvmqsdGglv.sieearkkpvetilSGPaaGvvgaaelsklegeeklIlfDmGGTstDislik 97 + + ++++ +++p y+ +s+ +++ ++ + v+ i+ P a + ++ +l+ge+++++fD+GG ++D+s++ FUN_000637-T1 137 LGQTVKNAVITVPAYFNDSQRQATkDAGMIAGLNVQRIINEPTAAALAYGLDKNLQGEKNVLIFDLGGGTFDVSVLT 213 55556666666777777776655424556677778999999****99999999********************9864 PP == domain 3 score: -2.0 bits; conditional E-value: 0.63 Hydantoinase_A 220 ianeemaeavrkvtvergldpse.ltlvvfGGaG..pqhaaalaeelgikkviv 270 e +++a+r+ +l++se + +v +GG+ p + ++l+e +g kk FUN_000637-T1 315 SCLEPVEKALRDA----KLEKSEiHEIVLVGGSTriPKVQKLLEEFFGGKKLNK 364 4444444444444....4444331444455555533444445555555555555 PP >> Radial_spoke_3 Radial spoke protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 3.5 3.6e-06 0.013 126 223 .. 514 613 .. 507 616 .. 0.83 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 3.6e-06 Radial_spoke_3 126 lkeekerrlkqqkealekeketeekiaaralakqylsellksvle.sLedkgyfyd.pvereveeeflpwLmeevekelekkkearelldsiiee 218 k+e +r +++ ++ +e ++ +ek+aar+ ++y+ ++++ + + +L+ k ++d + ++ ++e ++wL ++ ++e e+ ++ ++ l+++++ FUN_000637-T1 514 SKAEIDRMVADAEKYKEDDQRQREKVAARNSLENYVYSVKQAAEDpDLKGKLNTTDlETVTSKTREVMDWLENNSAAEKEDYERKEKDLQQVCSP 608 57899999999999999*********************9999977456655444442333455789**************************999 PP Radial_spoke_3 219 vvekr 223 ++ k+ FUN_000637-T1 609 IMAKA 613 88776 PP >> BcrAD_BadFG BadF/BadG/BcrA/BcrD ATPase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.0082 30 1 49 [. 9 58 .. 9 68 .. 0.84 2 ? 8.5 0.0 0.0005 1.8 217 270 .. 327 379 .. 267 380 .. 0.75 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.0082 BcrAD_BadFG 1 lGiDgGsTktkavlldeege.vlgraiagsaniesvgeeaaeknleeaie 49 +GiD+G+T + +++ ++ ++++ + + + + v++++ e+++ ea + FUN_000637-T1 9 IGIDLGTTYSCVGVFQHGKVeIIANDQGNRTTPSYVAFNETERLIGEAAK 58 7*******999999999998799998888888888888888888887765 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0005 BcrAD_BadFG 217 lgevkde...vvltGGvaknealvkalrdlvkekilevkvkvhpdpqyegaiGAaLl 270 + +k e +vl+GG + ++ +l++e ++++k + ++ p ++a GAa+ FUN_000637-T1 327 AKLEKSEiheIVLVGGSTRIPKVQ----KLLEEFFGGKKLNKTINPDEAVAYGAAVQ 379 3333333566**********4444....4478888888****************986 PP >> FtsA Cell division protein FtsA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.1 0.0032 12 2 27 .. 10 32 .. 9 159 .. 0.62 2 ? 5.7 0.1 0.0073 27 4 125 .. 201 373 .. 198 377 .. 0.59 3 ? 0.0 0.2 0.4 1.5e+03 33 79 .. 506 537 .. 493 607 .. 0.67 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0032 xxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 2 liDiGggttdiavfedgalrhtevip 27 +iD+G++ ++ vf++g++ +i+ FUN_000637-T1 10 GIDLGTTYSCVGVFQHGKVE---IIA 32 8***************9654...443 PP == domain 2 score: 5.7 bits; conditional E-value: 0.0073 xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxx......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 4 DiGggttdiavfedgalrhtevipv......ggngitkd......................iakglrtaveeAErlkikyGsalaseadeeeeevp 71 D+Gggt d++v ++ ev gg+ + + + + lrta e A+r FUN_000637-T1 201 DLGGGTFDVSVLTIDEGSLFEVRSTagdthlGGEDFDNRlvdhfaaefkrklktdikgnprALRRLRTASERAKRSL------------------- 277 78888888888765433333333332244457777777755566666666655555555555555555555555555................... PP xxxxxxxxxxxxxxxx..........................................................xxxxxxxxxxxxxxxxxxxxxx RF FtsA 72 gvggrepreisrkela..........................................................ggsalkglkelaeralglpvri 109 ++ ++ a g++ ++++++l+e+ +g FUN_000637-T1 278 --SSSTQ--------AsievdslaegidfhtkitrakfeelchdlfssclepvekalrdaklekseiheivlvgGSTRIPKVQKLLEEFFGG---- 359 ..11111........111122222333333333344455788999999999999999999999999999999999999********999933.... PP xxxxxxxxxxxxxxxx RF FtsA 110 gspkleevrnPeyata 125 kl++ nP a+a FUN_000637-T1 360 --KKLNKTINPDEAVA 373 ..22444555555555 PP == domain 3 score: 0.0 bits; conditional E-value: 0.4 xxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FtsA 33 itkd....iakglrtaveeAErlkikyGsalaseadeeeeevpgvggrepr 79 it+d + v++AE+ k ++++r+++ FUN_000637-T1 506 ITNDmgrlSKAEIDRMVADAEKYK-------------------EDDQRQRE 537 666666633334677888888888...................11222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (633 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1278 (0.0500294); expected 510.9 (0.02) Passed bias filter: 774 (0.0302995); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 6243.40 // Query: FUN_000639-T1 [L=897] Description: FUN_000639 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-85 286.9 0.0 6.3e-85 285.7 0.0 1.6 1 NAGidase beta-N-acetylglucosaminidase 3.4e-08 34.3 0.0 1.7e-07 32.0 0.0 2.3 1 Acetyltransf_1 Acetyltransferase (GNAT) family 3.5e-08 34.2 0.0 8.1e-06 26.6 0.0 2.4 2 Acetyltransf_7 Acetyltransferase (GNAT) domain 0.00053 20.4 0.0 0.0012 19.3 0.0 1.5 1 FR47 FR47-like protein 0.00059 20.3 0.0 0.0017 18.8 0.0 1.7 1 Acetyltransf_10 Acetyltransferase (GNAT) domain ------ inclusion threshold ------ 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 Orbi_NS1 Orbivirus non-structural protein NS1, or hyd 0.16 12.8 0.7 0.94 10.3 0.3 2.4 2 Gluconate_2-dh3 Gluconate 2-dehydrogenase subunit 3 Domain annotation for each model (and alignments): >> NAGidase beta-N-acetylglucosaminidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 285.7 0.0 1.7e-88 6.3e-85 2 280 .. 43 322 .. 42 340 .. 0.96 Alignments for each domain: == domain 1 score: 285.7 bits; conditional E-value: 1.7e-88 NAGidase 2 GviEGFYGkPWsheeRldllkflgehklntYiYaPkdDpyhrekWrepYpeeelkelkeLveaanenkvefvyalsPglsicysseedlkaliaKl 97 Gv+EGFYG+PW+ e+R++l++ l + k+ tY+YaPkdD +hr+ Wr++Y+ ee+++lk+L++ ++e +++f+yalsPgl+i +ss d+++l++K+ FUN_000639-T1 43 GVVEGFYGRPWTYEQRKELFSRLRHLKMTTYLYAPKDDLKHRALWRDLYTPEETENLKQLIASSKEYGIKFYYALSPGLDILFSSTRDIQQLKRKM 138 9*********************************************************************************************** PP NAGidase 98 eqlyelGvrsfailldDisyellhedadkeeaaaeaqaellnrvqkelkekkkdvkklivvpteYagse......eseylkelgekldkevevlwT 187 +q+ +lG+++fa+l+dDi+ +l d + ++ +eaq+e++n+++k l ++ ++pteY+g++ +s+yl +lg+kl+++++++wT FUN_000639-T1 139 SQVQKLGCEAFALLFDDIDPQLHGPDVESFRSFGEAQVEITNSIYKYLGC-----PNFLFCPTEYCGTRaipnveTSDYLLTLGSKLNPKINIMWT 229 *******************99888888888****************9987.....58***********99***999******************** PP NAGidase 188 GekvvskeiteeeaekaeevlgrklliwdNyPvnDyakerLllgpytgrepelakelagivanpmeqaeaskvalftaadylwnsekydaeks 280 G+kvvsk it++++e++++vl+rk++iwdN + nDy++ r++lgpy+gr el + l+g+++np + e + +a++t+a++l++s+ + +e+ FUN_000639-T1 230 GPKVVSKVITTQTIEALTTVLKRKPVIWDNIHANDYDQRRVFLGPYDGRPVELFPLLNGVLTNPNCEFESNFIAVHTLASWLRDSSLVTSEEP 322 ***********************************************************************************9987776664 PP >> Acetyltransf_1 Acetyltransferase (GNAT) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.0 0.0 4.5e-11 1.7e-07 60 116 .] 822 877 .. 716 877 .. 0.87 Alignments for each domain: == domain 1 score: 32.0 bits; conditional E-value: 4.5e-11 Acetyltransf_1 60 aeieglaVdpeyrgkGiGtaLlealleyarergcerlyleveedNeaaialYeklGF 116 a+ +++ p+++ G+G++Ll+ +l +++++c+ +++e++++N +a+++Y+klGF FUN_000639-T1 822 AH-VQIYLLPRAQDLGLGKRLLACVLSALKAEDCTGVHCEIATTNSGALDFYTKLGF 877 34.489****************************999*******************9 PP >> Acetyltransf_7 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.012 44 3 27 .. 745 769 .. 743 779 .. 0.81 2 ! 26.6 0.0 2.2e-09 8.1e-06 31 83 .. 823 878 .. 810 879 .. 0.69 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.012 Acetyltransf_7 3 erffVaeedgkivGfaallpeddea 27 e++fV+e++++ +Gfa+++ ++ ++ FUN_000639-T1 745 EHVFVVEDGDGRCGFAVATSDSKHF 769 79**************987776655 PP == domain 2 score: 26.6 bits; conditional E-value: 2.2e-09 Acetyltransf_7 31 eerlaVdpeyrgkGiGraLleaa.eaaakekgikll....elannneaarfYeklGFe 83 + +++ +p ++ G+G++Ll+ + a k++ ++ + ++n+ a fY klGF FUN_000639-T1 823 HVQIYLLPRAQDLGLGKRLLACVlS-ALKAEDCTGVhceiA-TTNSGALDFYTKLGFY 878 3469****************98853.444444533322222.34459999*******6 PP >> FR47 FR47-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 3.2e-07 0.0012 19 80 .. 818 880 .. 814 885 .. 0.85 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 3.2e-07 FR47 19 kdggelgalqvlpehrrrGlgsrlvkalakeiaergkt.vllvvvasNtpsrrlyeklGfeki 80 ++++ +++lp ++ Glg+rl + + ++ +++ t v ++++N+ + +y+klGf ki FUN_000639-T1 818 AKYSAHVQIYLLPRAQDLGLGKRLLACVLSALKAEDCTgVHCEIATTNSGALDFYTKLGFYKI 880 5566667899******************9999996655277889****************987 PP >> Acetyltransf_10 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 4.7e-07 0.0017 57 109 .. 826 880 .. 817 889 .. 0.88 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 4.7e-07 Acetyltransf_10 57 lfVdkeyqgqGiakaLlkaveeeaekddiel.eltvnssp.tavpfYeklGFvat 109 ++ +++q G++k+Ll+ v+++++ +d + + ++ ++ a +fY klGF ++ FUN_000639-T1 826 IYLLPRAQDLGLGKRLLACVLSALKAEDCTGvHCEIATTNsGALDFYTKLGFYKI 880 78899******************9888888789999998889**********876 PP >> Orbi_NS1 Orbivirus non-structural protein NS1, or hydrophobic tubular protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 1.2e-05 0.045 114 187 .. 502 576 .. 477 610 .. 0.77 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.2e-05 Orbi_NS1 114 esgvqeevkslrakerparvylDDslSllhyfyvPvnqgkivk.vtkvtRfgqflivfydreevdslipqderev 187 e ++ +v+++++k p++ +DD l l+ +fy+P+n+g+ k + + + +f + d++e ++l+ q+++ FUN_000639-T1 502 EQEIPMDVTEMKQKPAPTPLSTDDLLLLVDLFYLPYNHGQQAKqIVSDFKWLKFNAIKEDSQEFMELTEQEQKTK 576 5566778999****************************9876526677788888888777777777776666543 PP >> Gluconate_2-dh3 Gluconate 2-dehydrogenase subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.58 2.1e+03 93 116 .. 51 74 .. 21 78 .. 0.63 2 ? 10.3 0.3 0.00026 0.94 41 91 .. 539 587 .. 493 649 .. 0.81 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.58 Gluconate_2-dh3 93 eawkakaevrffnllkeltlegyf 116 w+ +++++ f+ l++l ++ y+ FUN_000639-T1 51 RPWTYEQRKELFSRLRHLKMTTYL 74 336667777888888888877775 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00026 Gluconate_2-dh3 41 lpeeqeafragLaaldaeakkrygksFaeltpeqqdalLkalekgakakee 91 ++++++ + +++l+ +a k+ ++F+elt+++q+ +++++++a++ FUN_000639-T1 539 HGQQAKQIVSDFKWLKFNAIKEDSQEFMELTEQEQKTKVSEWNEKAEK--F 587 5578899999*********************************99764..2 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (897 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1430 (0.0559796); expected 510.9 (0.02) Passed bias filter: 754 (0.0295165); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.46u 0.40s 00:00:00.86 Elapsed: 00:00:00.43 # Mc/sec: 8366.21 // Query: FUN_000640-T1 [L=644] Description: FUN_000640 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0022 18.2 8.4 0.0022 18.2 8.4 2.4 2 QWRF QWRF family ------ inclusion threshold ------ 0.25 11.7 5.9 0.21 11.9 2.3 2.4 2 DUF4391 Domain of unknown function (DUF4391) 0.29 11.9 0.7 1.2 9.9 0.7 2.0 1 Pepsin-I3 Pepsin inhibitor-3-like repeated domain 3.7 8.3 10.9 3.1 8.5 2.5 2.9 2 Cnn_1N Centrosomin N-terminal motif 1 Domain annotation for each model (and alignments): >> QWRF QWRF family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 3.3 1 6.5e+03 12 83 .. 94 163 .. 76 215 .. 0.49 2 ! 18.2 8.4 3.4e-07 0.0022 13 214 .. 280 524 .. 234 528 .. 0.63 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 1 QWRF 12 ievparflqeatssrlrrlsdpgsstsss.....sklksk.......kssldsatsssprsranslargsagssralSPsklss 83 i++p r+++++ s++r +s+++ + +s k + s +s + + s +r S+skl+ FUN_000640-T1 94 IKSPVRVVRHSPRSNTRNRSETSVIFEKSddrinV----TghldegrKLKVASVPSVNLLN---S-------NKRTKSSSKLLH 163 56667777776666666666666666555322220....2222211111111111111111...1.......223333333333 PP == domain 2 score: 18.2 bits; conditional E-value: 3.4e-07 QWRF 13 evparflqeatssrlrr..lsdpgsstsss....sklksk.......................kssldsatsssprsranslar.gsagss.ralS 77 vp+r+++++ sr ++p ++ +++ sklk++ k + + +s+p++ ++ ++ + +s+ + FUN_000640-T1 280 IVPSRYMEKTKVSRKVTekAPKPVKKAIKPlavsSKLKQQsvlhthsddstlnldiitpfaphKAQQKVIVTSTPADGVVGDQPlTQMASApTPIL 375 456666655222222112222222222222333322222233333344333333333333333555555556666666555443222222223334 PP QWRF 78 Psklss.....stsspsrglespsrprsssslkvss.....assgkgvasvlsfgaDvrrgKksesk...eedahqlRlLhNrlLQWRFvNAraea 160 P+ ++ + +++r + +++ +r +++++ +ss++g++++ls v ++ + ++ + ql l + r +Q F r + FUN_000640-T1 376 PQGIATavkarGGDAAARVI-KKTATRDKTKAQKGVrksqlSSSMQGAQQTLSSRPPVAKKVVHATPedtDVSQCQLELQYTRVMQATFLYSRLKH 470 44433356655455566655.333333333333231345677788888888888777766665554454456677899****************** PP QWRF 161 alsaqklaaekkLynawlriseLrnsvaekRielqklrqelKLasiLksQmklL 214 ++++++ a+ ++y +w++ +L++ va+ +el+++r+ L + L+ Q++ L FUN_000640-T1 471 SFAQKEKDAQAQIYSVWQEKEKLQREVANLETELKMKRKIAELDQHLHLQLSGL 524 ***********************************************9999876 PP >> DUF4391 Domain of unknown function (DUF4391) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 2.3 3.3e-05 0.21 121 218 .. 410 512 .. 380 525 .. 0.72 2 ? 0.2 0.1 0.13 8.1e+02 192 213 .. 587 608 .. 551 628 .. 0.65 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.3e-05 DUF4391 121 vleevfisawlpeeeellelesleeve..............kklnrtnlyalYqglldklialtaaeltgtfvledeeklderrerldeieeleke 202 v + +++s ++ ++++l + + ++ ++ l+ Y+ +++++++++ l+ f++++++ ++ +e e+l++e FUN_000640-T1 410 VRKSQLSSSMQGAQQTLSS-------RppvakkvvhatpedTDVSQCQLELQYTRVMQATFLYSR--LKHSFAQKEKDAQAQIYSVWQEKEKLQRE 496 4444444444422222222.......0233334577778888899999***************99..99*****6666666666778999****** PP DUF4391 203 iaklkkalkkekqfnr 218 +a+l+++lk ++++++ FUN_000640-T1 497 VANLETELKMKRKIAE 512 *********9988876 PP == domain 2 score: 0.2 bits; conditional E-value: 0.13 DUF4391 192 rldeieelekeiaklkkalkke 213 +++ei++ ke+++l+k +e FUN_000640-T1 587 KQQEIQTFAKEMDRLSKTVESE 608 3445555555555555555555 PP >> Pepsin-I3 Pepsin inhibitor-3-like repeated domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.7 0.00018 1.2 38 70 .. 582 614 .. 579 616 .. 0.93 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00018 Pepsin-I3 38 dLtseEqsELktydaevtkYkeelksslqervk 70 +Lt q+E++t+ +e+++ + ++s +qe+++ FUN_000640-T1 582 ELTKLKQQEIQTFAKEMDRLSKTVESEIQEQKR 614 899999************************986 PP >> Cnn_1N Centrosomin N-terminal motif 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 2.5 0.00048 3.1 24 68 .. 462 506 .. 459 517 .. 0.74 2 ? 3.4 1.4 0.019 1.2e+02 29 69 .. 582 622 .. 579 625 .. 0.82 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00048 Cnn_1N 24 hfleerleklapeqieellkenvelkveleslqkelkklkkllke 68 fl rl+ + ++ +++ + + +e+e+lq+e+++l+ +lk FUN_000640-T1 462 TFLYSRLKHSFAQKEKDAQAQIYSVWQEKEKLQREVANLETELKM 506 588888888888888888888888888888888888877777764 PP == domain 2 score: 3.4 bits; conditional E-value: 0.019 Cnn_1N 29 rleklapeqieellkenvelkveleslqkelkklkkllkea 69 +l kl++++i+ ke l ++es +e k++ +ll+ a FUN_000640-T1 582 ELTKLKQQEIQTFAKEMDRLSKTVESEIQEQKRCGELLAAA 622 68888889999999999999999999999988888888766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (644 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2116 (0.0828342); expected 510.9 (0.02) Passed bias filter: 744 (0.0291251); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.38u 0.37s 00:00:00.75 Elapsed: 00:00:00.40 # Mc/sec: 6454.31 // Query: FUN_000641-T1 [L=1092] Description: FUN_000641 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-13 50.5 0.1 4.3e-13 49.6 0.1 1.5 1 R3H R3H domain 5e-09 36.5 74.1 3.9e-06 27.3 12.3 14.8 15 zf-NF-X1 NF-X1 type zinc finger Domain annotation for each model (and alignments): >> R3H R3H domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.6 0.1 3.3e-17 4.3e-13 2 59 .. 963 1026 .. 962 1027 .. 0.88 Alignments for each domain: == domain 1 score: 49.6 bits; conditional E-value: 3.3e-17 R3H 2 flekleeklaefvkdt......gkslelppmssyeRriiHelaekygleseSeGeepnRrvvvy 59 fl+ +e+++++ v+ t ++s+++ +m+s +Rr+iHela y+ s+S+++ep+R +v++ FUN_000641-T1 963 FLKSVEDAFENLVQTTlklsvsQRSHSFSSMNSNQRRLIHELAVFYNCSSQSYDREPKRNTVIT 1026 788889999998877555555489**************************************97 PP >> zf-NF-X1 NF-X1 type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.3 0.019 2.4e+02 4 10 .. 393 399 .. 392 400 .. 0.97 2 ! 16.9 17.5 5.3e-07 0.0068 4 19 .] 410 425 .. 408 425 .. 0.95 3 ? -3.5 2.4 1.3 1.7e+04 6 10 .. 451 455 .. 451 455 .. 0.98 4 ! 15.1 9.9 2e-06 0.025 3 19 .] 463 479 .. 461 479 .. 0.91 5 ? -3.7 1.3 1.5 1.9e+04 6 10 .. 516 520 .. 515 520 .. 0.86 6 ! 27.3 12.3 3.1e-10 3.9e-06 1 19 [] 526 544 .. 526 544 .. 0.99 7 ! 15.5 8.7 1.5e-06 0.019 4 18 .. 604 618 .. 603 619 .. 0.95 8 ? -4.1 1.3 1.9 2.4e+04 5 10 .. 646 651 .. 646 651 .. 0.90 9 ? 2.1 9.9 0.022 2.8e+02 1 11 [. 657 667 .. 657 668 .. 0.95 10 ? 1.4 1.2 0.038 4.9e+02 4 10 .. 672 678 .. 671 678 .. 0.93 11 ! 22.5 11.7 9.2e-09 0.00012 1 18 [. 684 701 .. 684 702 .. 0.97 12 ? -3.7 0.9 1.4 1.8e+04 6 10 .. 731 735 .. 730 736 .. 0.68 13 ? -5.6 12.4 2 2.6e+04 8 19 .] 747 759 .. 738 759 .. 0.82 14 ! 6.7 15.5 0.00086 11 1 16 [. 795 809 .. 795 819 .. 0.86 15 ! 4.7 12.3 0.0034 44 1 18 [. 826 845 .. 826 846 .. 0.88 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.019 zf-NF-X1 4 HtCeelC 10 HtC elC FUN_000641-T1 393 HTCGELC 399 ******* PP == domain 2 score: 16.9 bits; conditional E-value: 5.3e-07 zf-NF-X1 4 HtCeelCHeGpCppCp 19 H+C++lCH+GpCp+Cp FUN_000641-T1 410 HRCNQLCHPGPCPSCP 425 ***************8 PP == domain 3 score: -3.5 bits; conditional E-value: 1.3 zf-NF-X1 6 CeelC 10 C+++C FUN_000641-T1 451 CQQVC 455 ***** PP == domain 4 score: 15.1 bits; conditional E-value: 2e-06 zf-NF-X1 3 nHtCeelCHeGpCppCp 19 H+C ++CH+G+C C+ FUN_000641-T1 463 THRCTRICHTGQCEDCQ 479 6***************6 PP == domain 5 score: -3.7 bits; conditional E-value: 1.5 zf-NF-X1 6 CeelC 10 C+++C FUN_000641-T1 516 CQSKC 520 99999 PP == domain 6 score: 27.3 bits; conditional E-value: 3.1e-10 zf-NF-X1 1 CGnHtCeelCHeGpCppCp 19 CGnH C+++CH+G+C+ Cp FUN_000641-T1 526 CGNHYCQRICHPGDCDECP 544 ******************8 PP == domain 7 score: 15.5 bits; conditional E-value: 1.5e-06 zf-NF-X1 4 HtCeelCHeGpCppC 18 H+C++ CH G+C+pC FUN_000641-T1 604 HRCKKECHFGECGPC 618 *************** PP == domain 8 score: -4.1 bits; conditional E-value: 1.9 zf-NF-X1 5 tCeelC 10 +Ce+ C FUN_000641-T1 646 RCERRC 651 7***99 PP == domain 9 score: 2.1 bits; conditional E-value: 0.022 zf-NF-X1 1 CGnHtCeelCH 11 CG+H+C + C+ FUN_000641-T1 657 CGKHKCGQRCC 667 **********8 PP == domain 10 score: 1.4 bits; conditional E-value: 0.038 zf-NF-X1 4 HtCeelC 10 H+Ce lC FUN_000641-T1 672 HRCELLC 678 ******* PP == domain 11 score: 22.5 bits; conditional E-value: 9.2e-09 zf-NF-X1 1 CGnHtCeelCHeGpCppC 18 CG H C+e+CH G CppC FUN_000641-T1 684 CGLHECSEPCHLGYCPPC 701 ****************** PP == domain 12 score: -3.7 bits; conditional E-value: 1.4 zf-NF-X1 6 CeelC 10 C ++C FUN_000641-T1 731 CDKPC 735 77777 PP == domain 13 score: -5.6 bits; conditional E-value: 2 zf-NF-X1 8 elCH.eGpCppCp 19 +CH e CppCp FUN_000641-T1 747 HPCHsEEKCPPCP 759 58998889****8 PP == domain 14 score: 6.7 bits; conditional E-value: 0.00086 zf-NF-X1 1 CGnHtCeelCHeGpCp 16 CG H+C+++CH+ pC FUN_000641-T1 795 CG-HKCQKICHKPPCL 809 **.*********9995 PP == domain 15 score: 4.7 bits; conditional E-value: 0.0034 zf-NF-X1 1 CGnHtCeelCHeGp.Cp..pC 18 CG H+C +CH G Cp pC FUN_000641-T1 826 CG-HKCAVPCHFGSgCPavPC 845 **.********9976888888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1092 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1219 (0.0477197); expected 510.9 (0.02) Passed bias filter: 349 (0.0136622); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.43u 0.38s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 10290.38 // Query: FUN_000642-T1 [L=881] Description: FUN_000642 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (881 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4404 (0.172402); expected 510.9 (0.02) Passed bias filter: 596 (0.0233314); expected 510.9 (0.02) Passed Vit filter: 218 (0.00853396); expected 25.5 (0.001) Passed Fwd filter: 85 (0.00332746); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 1.21u 0.46s 00:00:01.67 Elapsed: 00:00:00.51 # Mc/sec: 7007.32 // Query: FUN_000643-T1 [L=803] Description: FUN_000643 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.57 10.9 4.1 2 9.1 4.1 2.0 1 PEP-utilisers_N PEP-utilising enzyme, N-terminal 1.1 9.8 8.7 0.11 13.0 1.6 2.6 2 HypA Hydrogenase/urease nickel incorporation, met Domain annotation for each model (and alignments): >> PEP-utilisers_N PEP-utilising enzyme, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 4.1 0.00015 2 23 111 .. 250 341 .. 234 348 .. 0.82 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00015 PEP-utilisers_N 23 ekevaaedveaeierleaAlekareelealaeka..e.elgee.eaaifeahlmlleDpelleeveelIeeeglnAeaAvkevveeyaaqfea 111 k+ + e++ +e++ l++A ++++e+e l+ek+ + +e+ +++ +++ + l + + ++ve+ +++e+ + eaA ++++e+ + +e+ FUN_000643-T1 250 DKDREIEKIRNERNILREAAIRSEKEIEILSEKLnnLlHCKEQhKSSSVQTDASLSHEIQTCDSVEKTVNSEQ-SIEAAKQTTLEKDLRSLES 341 4445567899************************8634666663577***********************888.*******999987777766 PP >> HypA Hydrogenase/urease nickel incorporation, metallochaperone, hypA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.9 0.11 1.4e+03 42 100 .. 256 319 .. 212 328 .. 0.57 2 ? 13.0 1.6 8.7e-06 0.11 5 105 .. 362 479 .. 359 483 .. 0.85 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.11 HypA 42 ealefafevlakgtllegaeLei..eevpakarCrdCgkefelee..k.elkCpkCgsedveil 100 e ++ ++l++ + ++ e+ei e+ + ++C++ +k++++++ + +++ ++C+s + ++ FUN_000643-T1 256 EKIRNERNILREAAIRSEKEIEIlsEKLNNLLHCKEQHKSSSVQTdaSlSHEIQTCDSVEKTVN 319 4455555556666665555555511444456788888887776664324556778887766554 PP == domain 2 score: 13.0 bits; conditional E-value: 8.7e-06 HypA 5 slaesiveiveeeakeak..akkvkkvk.levGelsgvepealefafevlakgtllegaeLeieevpakarCrdCgkefeleekel.......... 87 s+++s+ ++++++ ++++ k++ ++ lev e +++++ fe + + + ++ +L+i++ ++++ C + ++ +e+++ ++ FUN_000643-T1 362 SIVKSMNDLIQNTNQQQQlaRKEIADLQlLEVSENCSITQNEQDVDFEQVDASRIQKEQTLTISDDSVSVDCCASSQMIETKQPAItqlelnlgrl 457 6888888888888855432367999998459*****************************************9999999988742245799***** PP HypA 88 .....kCpkCgsedveilsGeel 105 +C++C+ ++e ++G+++ FUN_000643-T1 458 sdldkTCEDCDP-QFESTEGQDV 479 **********86.6888888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (803 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2273 (0.0889802); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.45u 0.36s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 7693.39 // Query: FUN_000643-T2 [L=1115] Description: FUN_000643 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-09 37.7 0.4 3.8e-09 36.7 0.4 1.6 1 F-box-like F-box-like 7.3e-06 26.2 0.4 2.7e-05 24.4 0.4 2.1 1 F-box F-box domain ------ inclusion threshold ------ 1.1 9.9 4.2 3.4 8.4 4.2 1.8 1 PEP-utilisers_N PEP-utilising enzyme, N-terminal Domain annotation for each model (and alignments): >> F-box-like F-box-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.7 0.4 4.4e-13 3.8e-09 9 45 .. 799 835 .. 796 837 .. 0.94 Alignments for each domain: == domain 1 score: 36.7 bits; conditional E-value: 4.4e-13 F-box-like 9 LlqIFsyLdpkdLlrlalVCrrWrelasddsLWrrlc 45 Ll IF++L+p +L+ l +VCr Wr++ ++ LW+++ FUN_000643-T2 799 LLLIFQHLNPIELCGLERVCRVWRQMSEHPILWKEVI 835 9*********************************986 PP >> F-box F-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.4 3.2e-09 2.7e-05 7 42 .. 797 832 .. 796 833 .. 0.95 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 3.2e-09 F-box 7 ellleIlsrLdpkdllrlslVSkrwrslvkslklwk 42 ++ll I+++L+p++l+ l +V++ wr+ + lwk FUN_000643-T2 797 KCLLLIFQHLNPIELCGLERVCRVWRQMSEHPILWK 832 69*******************************997 PP >> PEP-utilisers_N PEP-utilising enzyme, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 4.2 0.0004 3.4 23 111 .. 250 341 .. 235 348 .. 0.82 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0004 PEP-utilisers_N 23 ekevaaedveaeierleaAlekareelealaeka..e.elgee.eaaifeahlmlleDpelleeveelIeeeglnAeaAvkevveeyaaqfea 111 k+ + e++ +e++ l++A ++++e+e l+ek+ + +e+ +++ +++ + l + + ++ve+ +++e+ + eaA ++++e+ + +e+ FUN_000643-T2 250 DKDREIEKIRNERNILREAAIRSEKEIEILSEKLnnLlHCKEQhKSSSVQTDASLSHEIQTCDSVEKTVNSEQ-SIEAAKQTTLEKDLRSLES 341 4445567899************************8634666663577***********************888.*******999987777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1664 (0.0651399); expected 510.9 (0.02) Passed bias filter: 431 (0.0168722); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.47u 0.38s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 10728.06 // Query: FUN_000644-T1 [L=341] Description: FUN_000644 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-52 178.0 2.9 2e-52 178.0 2.9 2.4 3 Glyco_transf_10 Glycosyltransferase family 10 (fucosyltransf 2.4e-22 79.9 0.4 3.4e-21 76.2 0.1 2.5 2 Glyco_tran_10_N Fucosyltransferase, N-terminal ------ inclusion threshold ------ 0.71 10.3 0.1 0.71 10.3 0.1 3.3 4 DM DM DNA binding domain Domain annotation for each model (and alignments): >> Glyco_transf_10 Glycosyltransferase family 10 (fucosyltransferase) C-term # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.11 9.2e+02 51 67 .. 87 103 .. 54 110 .. 0.79 2 ? -1.1 0.1 0.21 1.8e+03 128 144 .. 109 125 .. 104 133 .. 0.82 3 ! 178.0 2.9 2.4e-56 2e-52 2 179 .. 153 325 .. 152 328 .. 0.91 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.11 Glyco_transf_10 51 leeliksykFYLafEns 67 +++ k+ FY+ +En FUN_000644-T1 87 AQRTSKQIWFYFVLENP 103 57789999*******95 PP == domain 2 score: -1.1 bits; conditional E-value: 0.21 Glyco_transf_10 128 neeaYlkYfeWrkkykv 144 n++ Y + f+W +y+ FUN_000644-T1 109 NDDGYANVFNWTMSYSR 125 8899*******999976 PP == domain 3 score: 178.0 bits; conditional E-value: 2.4e-56 Glyco_transf_10 2 kkkkklvawvvsnckteskRvkyvkeLkkhievdvyGkcgklk....elsekeleeliksykFYLafEnslckDYiTeKlw.naleagavPvvl 90 ++k+k+vaw+vsnc + ++R +yv+eLk++i+++vyG cg ++ + +++ ++ l++++kFYLafEn +c +YiTeK w na++++++Pvv+ FUN_000644-T1 153 ATKDKKVAWLVSNCYA-TERREYVEELKEYIDISVYGLCGDKRscpaRRHSSVCNALLRRHKFYLAFENGNCPEYITEKYWvNAIDNNILPVVM 245 689***********98.67889*******************9999988888889999************************************* PP Glyco_transf_10 91 gpsranyerfvppdsfihvddFksakeLaeyLkkldkneeaYlkYfeWrkkykvkklsseeekalsselCklCeklkekeee..ekvvkdl 179 g +a+y++++ p+s+i+v+dF+s+k+LaeyL +ld+n++aY+kYf+W++ y+ k C+lC++l++k+ +++k++ FUN_000644-T1 246 G--GADYKALAIPNSYINVKDFESPKKLAEYLLYLDRNDTAYQKYFTWKRFYQHVPP-----K----FACSLCKQLHNKSLLasPRMYKNM 325 *..**************************************************9444.....2....36********99864335666665 PP >> Glyco_tran_10_N Fucosyltransferase, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.2 0.1 4e-25 3.4e-21 3 109 .] 17 134 .. 15 134 .. 0.84 2 ? 1.2 0.0 0.081 6.9e+02 27 45 .. 162 180 .. 137 223 .. 0.74 Alignments for each domain: == domain 1 score: 76.2 bits; conditional E-value: 4e-25 Glyco_tran_10_N 3 kkliLlwtkpfgkkfele..................kCselfeveeCeltedrslleeadavvfhhrdisidlkdlpkkkRppsqrwvwfnlEs 78 +kliLl+t fg +++ + +C ev++C +t++++++ eadav fh rd + lp ++R+++q+w +f lE+ FUN_000644-T1 17 RKLILLFTPFFGAEWRDHstlgpsstyflegrqtfkDC----EVSSCAVTYNKEKIMEADAVGFHARD---MPSILP-AQRTSKQIWFYFVLEN 102 68999999977664444445567788888888666677....9*************************...578888.8*************** PP Glyco_tran_10_N 79 Psn.skkleelenlfNltmtYrrdsdiflpYg 109 Psn + +++ n+fN+tm+Y r+s+i++pYg FUN_000644-T1 103 PSNvFINDDGYANVFNWTMSYSRNSEIYTPYG 134 ***633456899*******************8 PP == domain 2 score: 1.2 bits; conditional E-value: 0.081 Glyco_tran_10_N 27 eveeCeltedrslleeada 45 v++C+ te r+ +ee + FUN_000644-T1 162 LVSNCYATERREYVEELKE 180 6899****99999977654 PP >> DM DM DNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.1 8.3e-05 0.71 25 46 .. 50 71 .. 47 72 .. 0.93 2 ? -3.1 0.0 1.3 1.1e+04 33 41 .. 165 173 .. 164 176 .. 0.72 3 ? 0.9 0.3 0.071 6.1e+02 14 32 .. 206 224 .. 191 230 .. 0.77 4 ? -1.3 0.1 0.34 2.9e+03 4 10 .. 303 309 .. 301 317 .. 0.61 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 8.3e-05 DM 25 rykdCeCekCllveeRqkvmaa 46 ++kdCe ++C+++ ++ k+m a FUN_000644-T1 50 TFKDCEVSSCAVTYNKEKIMEA 71 69******************86 PP == domain 2 score: -3.1 bits; conditional E-value: 1.3 DM 33 kCllveeRq 41 +C+ +e+R FUN_000644-T1 165 NCYATERRE 173 799997775 PP == domain 3 score: 0.9 bits; conditional E-value: 0.071 DM 14 ivplkGHkryCrykdCeCe 32 + l+ Hk y +++ +C+ FUN_000644-T1 206 NALLRRHKFYLAFENGNCP 224 3478999999999999997 PP == domain 4 score: -1.3 bits; conditional E-value: 0.34 DM 4 kCarCrn 10 C+ C++ FUN_000644-T1 303 ACSLCKQ 309 4666765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (341 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 584 (0.0228616); expected 510.9 (0.02) Passed bias filter: 430 (0.016833); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 3460.22 // Query: FUN_000645-T1 [L=364] Description: FUN_000645 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-26 92.1 18.4 4.6e-16 59.6 6.2 2.6 3 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.018 15.2 0.1 0.051 13.8 0.1 1.8 1 DUF7535 Family of unknown function (DUF7535) 0.05 13.9 0.2 0.05 13.9 0.2 2.1 3 DUF443 Protein of unknown function (DUF443) 0.11 12.4 0.5 0.57 10.1 0.2 2.3 2 Zn_ribbon_ZPR1 ZPR1 zinc-finger domain 0.18 13.0 0.0 0.37 12.1 0.0 1.4 1 Kre9_KNH1_C Yeast cell wall synthesis protein KRE9/KNH1 C Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.1 5.2e+02 183 228 .. 11 56 .. 6 66 .. 0.73 2 ! 59.6 6.2 9e-20 4.6e-16 2 116 .. 48 165 .. 47 176 .. 0.86 3 ! 39.9 3.9 8.9e-14 4.6e-10 138 260 .] 162 299 .. 161 299 .. 0.77 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.1 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 183 sakkekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsl 228 ++ ++++++ ++++++++++ +v+ ++f l+ + + +ll++ FUN_000645-T1 11 HEHEHEHEHDLGFSATAEVATVAGVLSLTFGLATIVTNSVLLFTLC 56 4555555666777778899999999999999999999997666554 PP == domain 2 score: 59.6 bits; conditional E-value: 9e-20 xxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkk...lrtptnifllnLavaDllvlllvlpfalvyal.legdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplky 93 N +++++++++ l + t++f+ +L+v+D+l +++v p+ v + +++++ + lC++ + v++ +si++++a+s+DRYla+ +y FUN_000645-T1 48 NSVLLFTLCKDPCnyfLSRGTTYFIASLSVSDFLAGFVVQPLYSVCMFsSAQQKPI-SKLCEISLISSHVTTKVSIFTVVALSLDRYLAVKLSWRY 142 777777777766655578899********************998777724555566.556************************************ PP xxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalll 116 ++++t r+++v+ ++vW+++ ++ FUN_000645-T1 143 NSLVTVRKVTVCNIGVWLFCGIF 165 ******************98876 PP == domain 3 score: 39.9 bits; conditional E-value: 8.9e-14 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 138 Clidfpeeest.wevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks..........kkkksarkerkalktllvvvvvfvlcwlPyfil 222 C i ++++ +e+ ++l+ + l +pl++++ +y+ ++++ r+++++ ++ ++ r e+k++ t+l++++v ++ lPy+i+ FUN_000645-T1 162 CGIFEATHSEVdSESAFHLIDLHLQTTVPLIILCAIYTATYHEFRRHSRNVVFvqsnadgrsrTSIRNIRLEKKIVWTILMIIIVLFISLLPYLIT 257 666555544445999999*******************************996655555554434444555566*********************** PP xxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 223 llldsl.....lkeceseklvetallitlllayvnsclNPiiY 260 + l+ ++ec+++ + + ++ +++ l +v++ lNP++Y FUN_000645-T1 258 NNLEERcfekgSSECSQSSF-TSVKVLSIPLLCVSCSLNPFLY 299 *9998876764444444443.34556677788999*******9 PP >> DUF7535 Family of unknown function (DUF7535) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.1 9.9e-06 0.051 28 50 .. 236 258 .. 233 267 .. 0.85 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 9.9e-06 DUF7535 28 iGwavflvllvllvPLLPFiviv 50 i w+++++++vl++ LLP+++ FUN_000645-T1 236 IVWTILMIIIVLFISLLPYLITN 258 67******************975 PP >> DUF443 Protein of unknown function (DUF443) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.2 0.81 4.2e+03 86 117 .. 108 139 .. 94 169 .. 0.58 2 ? -2.4 0.1 0.94 4.8e+03 81 101 .. 177 197 .. 141 203 .. 0.71 3 ? 13.9 0.2 9.8e-06 0.05 80 149 .. 223 293 .. 220 305 .. 0.78 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 0.81 DUF443 86 diqleklvviiivlivlllvlvlriyinkklk 117 +i l + v+ v i ++++l+l y+ kl+ FUN_000645-T1 108 EISLISSHVTTKVSIFTVVALSLDRYLAVKLS 139 44444445555555555555555555544444 PP == domain 2 score: -2.4 bits; conditional E-value: 0.94 DUF443 81 lidlfdiqleklvviiivliv 101 +l+d++l++ v +ii++ + FUN_000645-T1 177 AFHLIDLHLQTTVPLIILCAI 197 456777788877777777665 PP == domain 3 score: 13.9 bits; conditional E-value: 9.8e-06 DUF443 80 klidlfdiqleklvviiivlivlllvlvlriy.inkklkkklynevelekkskekiiiipkslknlllllf 149 + + + +i lek +v+ i++i+++l ++l y i ++l+++ +++ ++e ++++ +++ s+ l++ + FUN_000645-T1 223 SRTSIRNIRLEKKIVWTILMIIIVLFISLLPYlITNNLEERCFEKGSSECSQSSFTSVKVLSIPLLCVSCS 293 567888************99999999988766267788999999988887777777777777777776665 PP >> Zn_ribbon_ZPR1 ZPR1 zinc-finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.037 1.9e+02 10 26 .. 270 286 .. 263 289 .. 0.88 2 ? 10.1 0.2 0.00011 0.57 2 45 .. 282 325 .. 281 332 .. 0.82 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.037 Zn_ribbon_ZPR1 10 mnCgkngetrmlltkIP 26 ++C++ t +++++IP FUN_000645-T1 270 SECSQSSFTSVKVLSIP 286 68**************9 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00011 Zn_ribbon_ZPR1 2 veslpteCmnCgkngetrmlltkIPyFkev..iimsfeCdhCgykn 45 v+s+p C++C+ n ++ kIP++k+ ++ +C +C +n FUN_000645-T1 282 VLSIPLLCVSCSLNP--FLYAWKIPHYKQSlrLVANRTCSKCLRQN 325 8899999****9775..5899*******9733588899*9997666 PP >> Kre9_KNH1_C Yeast cell wall synthesis protein KRE9/KNH1 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 7.2e-05 0.37 18 71 .. 95 148 .. 89 157 .. 0.89 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 7.2e-05 Kre9_KNH1_C 18 fAPmQtqPgtkvtattwsrrfptsavtyysslkksleqltTiTpgwsytvtsav 71 f Q++P +k+ + + + t++v+ ++ ++ sl+ + + +w y+ +v FUN_000645-T1 95 FSSAQQKPISKLCEISLISSHVTTKVSIFTVVALSLDRYLAVKLSWRYNSLVTV 148 7778********************************************876555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (364 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1127 (0.0441182); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3547.20 // Query: FUN_000646-T1 [L=114] Description: FUN_000646 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (114 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 589 (0.0230573); expected 510.9 (0.02) Passed bias filter: 551 (0.0215698); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.35s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1138.51 // Query: FUN_000856-T1 [L=252] Description: FUN_000856 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-29 101.4 0.4 4.2e-29 101.4 0.4 1.7 2 PAP2 PAP2 superfamily ------ inclusion threshold ------ 0.072 14.0 0.7 0.18 12.7 0.1 1.9 2 EhaL Energy-converting hydrogenase subunit EhaL 0.092 12.6 0.8 0.34 10.8 0.0 2.0 2 LrgB LrgB-like family 2.1 8.5 3.4 0.93 9.7 0.5 1.8 2 DUF4131 Domain of unknown function (DUF4131) 4.8 8.1 5.2 0.78 10.6 0.6 2.1 2 HRG Haem-transporter, endosomal/lysosomal, haem-respons Domain annotation for each model (and alignments): >> PAP2 PAP2 superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 2 1e+04 80 90 .. 41 51 .. 20 54 .. 0.58 2 ! 101.4 0.4 8.3e-33 4.2e-29 3 127 .. 65 206 .. 63 210 .. 0.94 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 2 PAP2 80 vllallllvla 90 v+ ++++++la FUN_000856-T1 41 VVPFAVIIILA 51 33333344433 PP == domain 2 score: 101.4 bits; conditional E-value: 8.3e-33 PAP2 3 lilllalalaglltsvlKdlvgrpRPdflaeegglvtasstlees..........kksfPSgHsatafalalllalllrrlrkkag........rv 80 l+l l+l+l+g++t+++K+lvgrpRPd+ +++ ++ + +l+ + +ksfPSgHs++af+++ +l+l+l+ + + ++ ++ FUN_000856-T1 65 LALTLTLGLNGVITNMIKVLVGRPRPDYFWRCYPNGAIPLSLK-CdgnpdeiiegRKSFPSGHSSFAFSGLGFLSLYLAGKLHCFQtqgrsqgwKL 159 678999*****************************99976655.4599***********************************9999******999 PP PAP2 81 llallllvlallvglsRlylgaHfpsDvlaGlllGillallvyrlvq 127 +al+++ al+ +l+R+++++H++ D+++G++lG+l+ +++yr+++ FUN_000856-T1 160 CAALAPVACALALALTRYSDYRHHWQDIVVGSMLGLLFSYVCYRQYY 206 999*****************************************986 PP >> EhaL Energy-converting hydrogenase subunit EhaL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 0.88 4.5e+03 37 52 .. 35 51 .. 20 80 .. 0.54 2 ? 12.7 0.1 3.5e-05 0.18 10 29 .. 187 206 .. 180 214 .. 0.90 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.88 EhaL 37 laLvlavlGwll.lnas 52 l ++ +v+ ++ + + FUN_000856-T1 35 LFVISSVVPFAViIILA 51 33444454444423333 PP == domain 2 score: 12.7 bits; conditional E-value: 3.5e-05 EhaL 10 fivGsllGLeysyrkykepy 29 +vGs+lGL++sy y++ y FUN_000856-T1 187 IVVGSMLGLLFSYVCYRQYY 206 59**************9988 PP >> LrgB LrgB-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.2 0.14 7.2e+02 189 207 .. 59 81 .. 32 86 .. 0.63 2 ? 10.8 0.0 6.6e-05 0.34 51 95 .. 159 202 .. 132 214 .. 0.85 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.14 LrgB 189 egafss....lamvlagiltall 207 g+ +s l+++l+g++t ++ FUN_000856-T1 59 DGVQASlaltLTLGLNGVITNMI 81 44444400014456677777665 PP == domain 2 score: 10.8 bits; conditional E-value: 6.6e-05 LrgB 51 lsflLgpatVaLAvpLykqlellkknllpillgllvgslvailsa 95 l + L p+ aLA+ L + + ++++ i++g ++g l++ +++ FUN_000856-T1 159 LCAALAPVACALALALTRYSDY-RHHWQDIVVGSMLGLLFSYVCY 202 556899999*******987765.******************9986 PP >> DUF4131 Domain of unknown function (DUF4131) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 0.67 3.4e+03 13 30 .. 42 58 .. 33 80 .. 0.48 2 ? 9.7 0.5 0.00018 0.93 5 58 .. 157 212 .. 153 224 .. 0.62 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.67 DUF4131 13 llllllllllllrrkrrr 30 + ++++++l++l rk FUN_000856-T1 42 VPFAVIIILAIL-RKDNI 58 333333333333.33333 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00018 DUF4131 5 lplwllaallllllllllllr...rkrrrtllllllllllavlgaalraprpnsndl 58 ++l++++a ++ +l+l+l ++ r+++ +++ ++l l+++++++r+++p+ n+ FUN_000856-T1 157 WKLCAALAPVACALALALTRYsdyRHHWQDIVVGSMLG-LLFSYVCYRQYYPALNRP 212 44444444444444444444477777777776666555.556777788887777665 PP >> HRG Haem-transporter, endosomal/lysosomal, haem-responsive gene # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.6 0.00015 0.78 5 41 .. 30 67 .. 29 73 .. 0.83 2 ? -2.6 0.4 2 1e+04 9 22 .. 188 201 .. 187 202 .. 0.75 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00015 HRG 5 iavgifgsllglsaflvflvlAiyrkqsltd.prSlyl 41 i+v ++++ +++ f+v+++lAi rk+ + Sl l FUN_000856-T1 30 ISVEMLFVISSVVPFAVIIILAILRKDNIDGvQASLAL 67 678999*********************65544466665 PP == domain 2 score: -2.6 bits; conditional E-value: 2 HRG 9 ifgsllglsaflvf 22 ++gs+lgl+ v+ FUN_000856-T1 188 VVGSMLGLLFSYVC 201 68999999877766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (252 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 835 (0.0326874); expected 510.9 (0.02) Passed bias filter: 646 (0.0252887); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2468.81 // Query: FUN_000856-T2 [L=204] Description: FUN_000856 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-21 75.3 0.3 5.1e-21 75.3 0.3 1.5 2 PAP2 PAP2 superfamily Domain annotation for each model (and alignments): >> PAP2 PAP2 superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 0.28 7e+03 80 90 .. 41 51 .. 19 54 .. 0.55 2 ! 75.3 0.3 2e-25 5.1e-21 3 106 .. 65 185 .. 63 200 .. 0.93 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 0.28 PAP2 80 vllallllvla 90 v+ ++++++la FUN_000856-T2 41 VVPFAVIIILA 51 33334444444 PP == domain 2 score: 75.3 bits; conditional E-value: 2e-25 PAP2 3 lilllalalaglltsvlKdlvgrpRPdflaeegglvtasstlees..........kksfPSgHsatafalalllalllrrlrkkag........rv 80 l+l l+l+l+g++t+++K+lvgrpRPd+ +++ ++ + +l+ + +ksfPSgHs++af+++ +l+l+l+ + + ++ ++ FUN_000856-T2 65 LALTLTLGLNGVITNMIKVLVGRPRPDYFWRCYPNGAIPLSLK-CdgnpdeiiegRKSFPSGHSSFAFSGLGFLSLYLAGKLHCFQtqgrsqgwKL 159 678999*****************************99976655.4599***********************************9999******999 PP PAP2 81 llallllvlallvglsRlylgaHfps 106 +al+++ al+ +l+R+++++H++ FUN_000856-T2 160 CAALAPVACALALALTRYSDYRHHWQ 185 999*********************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (204 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 875 (0.0342533); expected 510.9 (0.02) Passed bias filter: 606 (0.0237228); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2053.18 // Query: FUN_000857-T1 [L=376] Description: FUN_000857 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-131 437.7 0.0 4.6e-130 434.4 0.0 1.9 1 Actin Actin ------ inclusion threshold ------ 0.1 13.4 0.0 0.16 12.8 0.0 1.3 1 Monooxy_af470-like Monooxygenase af470-like 0.15 11.4 0.0 10 5.3 0.0 2.2 2 MreB_Mbl MreB/Mbl protein Domain annotation for each model (and alignments): >> Actin Actin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 434.4 0.0 5.4e-134 4.6e-130 4 409 .. 9 375 .. 7 376 .] 0.98 Alignments for each domain: == domain 1 score: 434.4 bits; conditional E-value: 5.4e-134 Actin 4 vsaiVlDvGssttraGyagedaPkavipsvvgkprgekvea.....klyvgdealekrpglevrspvedGvvedwdavekiwehvlkee.lqvdpe 93 +++iV+D+Gs +++aG+ag+++Pk+ +p++vg+p++ +v+a ++++g +a e+r+ l++r+p+e+Gvv dw+++e+iw+++++++ lq+ +e FUN_000857-T1 9 NQPIVIDNGSGVIKAGFAGDQTPKYHFPNFVGRPKHVRVMAgalegDIFIGPKAEEHRGLLNIRYPMEHGVVRDWNDMERIWQYIYSKDqLQTFSE 104 689*************************************9*********************************************9988****** PP Actin 94 ehpllltepalnpranrekaleimfEkfkvpalylaknavlsafasgkatalvvDsGasvtsvvpvldGyvLkkavrrsdlgGeaLteqlkellss 189 ehp+llte++lnpr nreka+ei+fE+f+vpal+++++avls++a+g++t++v+DsG++v++ vp+++G+++ ++++r d++G+++t l+ ll++ FUN_000857-T1 105 EHPVLLTEAPLNPRRNREKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVSHSVPIYEGFAMPHSIMRTDIAGRDITTFLRLLLRK 200 ************************************************************************************************ PP Actin 190 knievtPrylikkkkvvekeesaekeelekltesyktleeeevleeiKesvcevsedpekdeetsssspeksyelPDgstielgeerfrvpElLFn 285 + + ++++ +e+e++++iKe+vc+ + +p+ +e+s +s++ +y+lPDgs +e+g++rfr+pElLF+ FUN_000857-T1 201 E------------------------------GFNFHSSSEMEIVRTIKERVCYLALNPQ--KEESIDSERIQYVLPDGSMLEVGPARFRAPELLFR 264 7..............................789************************9..45555678889************************ PP Actin 286 psllgeeseleeekkkkllgiselivaainacdvdlrkeLlanivvtGGtsllpglteRlekelaelapkgvkvkiiaaentverkysaWiGGSiL 381 p+l+gee e gi+e++ ai+++d dlr+ L++niv++GG++l++g+ +Rl +e++++apk+ k++i a++ er ys+WiGGSiL FUN_000857-T1 265 PDLVGEECE----------GIHEVLAFAIQKSDLDLRRVLYSNIVLSGGSTLFKGFGDRLLSEVKKVAPKDIKIRISAPQ---ERLYSTWIGGSIL 347 ******988..........*************************************************************...************* PP Actin 382 AslgtfqqlwvskqeYeEqGasvverkc 409 Asl+tf+++wvsk+eY+++Ga++++rk+ FUN_000857-T1 348 ASLDTFKKMWVSKKEYDDEGARAIHRKT 375 **************************98 PP >> Monooxy_af470-like Monooxygenase af470-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 1.9e-05 0.16 38 103 .. 65 136 .. 47 155 .. 0.81 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.9e-05 Monooxy_af470-like 38 elGlLgaesyll......asrevllvqYwrsveeLeafAheelHreawkefnkkvkksghvgifHEtYvvea 103 + GlL+ + + ++ + qY s ++L+ f++e++ + + + +n + +++++ +if Et+ v+a FUN_000857-T1 65 HRGLLNIRYPMEhgvvrdWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEIFFETFNVPA 136 556666655442245553344556789**************9999999*********************986 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.0012 10 58 97 .. 70 109 .. 57 126 .. 0.82 2 ? 3.8 0.0 0.0036 31 258 297 .. 280 318 .. 266 332 .. 0.71 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0012 MreB_Mbl 58 kavrPlkdGviadlevaeellkyfikkvkkkkslskprvv 97 ++ P+++Gv+ d + e++ +y+ +k + +++ ++ v+ FUN_000857-T1 70 NIRYPMEHGVVRDWNDMERIWQYIYSKDQLQTFSEEHPVL 109 5667*********************999887776655554 PP == domain 2 score: 3.8 bits; conditional E-value: 0.0036 MreB_Mbl 258 kevLektppeLaadivdrgivltGGgallkgldkllseet 297 + +++k +L ++ ivl+GG++l+kg+ + l +e+ FUN_000857-T1 280 AFAIQKSDLDLRR-VLYSNIVLSGGSTLFKGFGDRLLSEV 318 5555555555554.55567*************77766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (376 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 468 (0.0183206); expected 510.9 (0.02) Passed bias filter: 462 (0.0180857); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 3802.67 // Query: FUN_000858-T1 [L=639] Description: FUN_000858 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-12 46.8 1.7 4.1e-12 46.8 1.7 2.2 3 bMERB_dom Bivalent Mical/EHBP Rab binding domain 4.7e-07 30.0 0.2 1.3e-06 28.6 0.2 1.8 1 NT-C2 N-terminal C2 in EEIG1 and EHBP1 proteins ------ inclusion threshold ------ 0.049 14.4 0.2 0.61 10.9 0.1 2.5 2 DUF7240 Family of unknown function (DUF7240) 0.23 12.2 0.0 0.51 11.1 0.0 1.6 1 Pertus-S4-tox Pertussis toxin S4 subunit Domain annotation for each model (and alignments): >> bMERB_dom Bivalent Mical/EHBP Rab binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.9 1.1 7.3e+03 65 100 .. 288 323 .. 285 327 .. 0.67 2 ? -4.1 0.1 3.5 2.2e+04 27 41 .. 480 492 .. 472 499 .. 0.47 3 ! 46.8 1.7 6.4e-16 4.1e-12 2 115 .. 521 636 .. 520 637 .. 0.93 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 1.1 bMERB_dom 65 akeqeLeeeqaeleqelrellekedkekteedkkre 100 +k++ L +e ++l +e + + k + + ++k++e FUN_000858-T1 288 MKQLALASEASSLTKEKVKKMCKGHETSNFKKKEKE 323 688889999999999888877776444444444444 PP == domain 2 score: -4.1 bits; conditional E-value: 3.5 bMERB_dom 27 Reesesgeeeeeell 41 R + ++ eeee++ l FUN_000858-T1 480 R-D-ADAEEEEKQRL 492 4.2.33344444444 PP == domain 3 score: 46.8 bits; conditional E-value: 6.4e-16 bMERB_dom 2 qreleeieeeqkeleergvelEkkLR..eesesgeeeeeelleewfeLvneknaLvrreseLmilakeqeLeeeqaeleqelrellekedkektee 95 ++e++ + + ++++++ +lE+++ ++ ++ +ee + l+++w++L+ + +L++r + L+ilak ++ e++ + l+ +l+ ll+ ed++kt+ FUN_000858-T1 521 AEEMNSLRNGIAAVDKVLLKLEREIQqtMNIADCTEEYKGLTQDWLTLIDYRGELTSRRNTLQILAKGEDFEQCCRILRDDLKVLLTLEDWKKTAF 616 5788899999999999999*******87666677778888******************************************************** PP bMERB_dom 96 dkkreeelleelveiVekRd 115 +k ++ +ll+ +++ V+k+ FUN_000858-T1 617 HKGQQAKLLQLIFTFVNKKQ 636 *****************986 PP >> NT-C2 N-terminal C2 in EEIG1 and EHBP1 proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 0.2 2e-10 1.3e-06 2 135 .. 13 157 .. 12 164 .. 0.78 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 2e-10 NT-C2 2 krkikfqfelkihelqnlpl....eggelfvkw.krgdkkgssgttekalvkngrakfn..eelsipvtlfld...kkgkkyeeKllelsvykvtk 87 k++ fq+++++++l+ + + ++++ w k g +k+s ++ + g+++ +++++++t +l+ +++++ye l + + ++tk FUN_000858-T1 13 KNARVFQITASVNSLKLECRknvwHPRKVVILWdKIGHSKTSPWQPGAHDLFFGNVISPpvDPVTFTCTTTLNknlERKGTYEGQPLNFFIKNETK 108 677889999999999999999999999999999999999999999999999999999999966666666666655866668*************** PP NT-C2 88 kgkkkvlGkvslDLaeyanlk...kkpttvslllkkskkknatlslsiqlk 135 g++kv+++ s+DLa ++n+k k + lk k+ + s+s++++ FUN_000858-T1 109 RGWRKVIATGSIDLAGHINKKsleK--FYTTVALKPATKNVVSGSISFKMS 157 *******************998444..444444444444555555555444 PP >> DUF7240 Family of unknown function (DUF7240) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.18 1.2e+03 41 69 .. 415 443 .. 408 472 .. 0.74 2 ? 10.9 0.1 9.6e-05 0.61 37 72 .. 472 507 .. 468 527 .. 0.81 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.18 DUF7240 41 esltsgakkkeeakeelesyldkLYkPdt 69 e+++++a+ + +ke+l+ +++kL k + FUN_000858-T1 415 EQTSADADAEGMEKEKLTCFFNKLLKGSP 443 5566777888889999********98544 PP == domain 2 score: 10.9 bits; conditional E-value: 9.6e-05 DUF7240 37 klvlesltsgakkkeeakeelesyldkLYkPdteak 72 ++ +esl +a+ +ee+k++l s+++kL kP ++++ FUN_000858-T1 472 SVQIESLPRDADAEEEEKQRLASFFNKLIKPAPHKA 507 678999*************************99832 PP >> Pertus-S4-tox Pertussis toxin S4 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 8e-05 0.51 34 61 .. 248 275 .. 212 293 .. 0.72 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8e-05 Pertus-S4-tox 34 aaklgaaasspdahvpfcfgkdlkrpgs 61 + +a s dah+pfc gk ++ FUN_000858-T1 248 ENEEKKSACSEDAHIPFCKGKKRNKGRK 275 555567899***********98765544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (639 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1523 (0.0596203); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.39u 0.41s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 6033.20 // Query: FUN_000859-T1 [L=598] Description: FUN_000859 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-215 716.7 1.1 2.3e-215 716.5 1.1 1.0 1 Glyco_hydro_63 Glycosyl hydrolase family 63 C-terminal doma 2e-26 93.9 0.0 4.1e-26 92.9 0.0 1.5 1 MGH1-like_GH Mannosylglycerate hydrolase MGH1-like glycos 0.0042 16.5 0.1 0.0099 15.3 0.0 1.6 1 Trehalase Trehalase ------ inclusion threshold ------ 0.018 14.5 0.1 0.038 13.4 0.1 1.6 2 GDE_C Amylo-alpha-1,6-glucosidase 0.083 12.6 0.0 0.2 11.4 0.0 1.6 1 Bac_rhamnosid6H Bacterial alpha-L-rhamnosidase 6 hairpin gly Domain annotation for each model (and alignments): >> Glyco_hydro_63 Glycosyl hydrolase family 63 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 716.5 1.1 4.6e-219 2.3e-215 7 492 .] 118 596 .. 112 596 .. 0.96 Alignments for each domain: == domain 1 score: 716.5 bits; conditional E-value: 4.6e-219 Glyco_hydro_63 7 eeklekkkkefeekfekkFklkekdlekeelklakaalsnllGgigyfyGsslvkresvleedefvkykpaeLftavPsRpfFPRGFlWDeGFhq 101 e+ e +++f++kfe+kF+l++k+++++++++a+aalsn++GgigyfyGss+v s++ + ++v+y++ +L+tavPsRpfFPRGFlWDeGFhq FUN_000859-T1 118 ESLREFYSQQFDRKFEEKFSLTSKGFSEKQVQFAQAALSNMVGGIGYFYGSSKVI--SRFFK-KPVDYWDSPLYTAVPSRPFFPRGFLWDEGFHQ 209 555566789*********************************************9..56644.79****************************** PP Glyco_hydro_63 102 lliskwdsdltleilasWldllnadGWipReqilgaearskvPeefvvqkpeianPPtlllalkklleklklekvsekekeklleflkklyprlk 196 llis+wd +++ +i+++Wldl+n +GWipReqilg+ear+kvP++fvvq++e+anPPtl+l++k++++k l+ +l+k++prlk FUN_000859-T1 210 LLISQWDESISKDIIGHWLDLINIEGWIPREQILGDEARTKVPSDFVVQHNENANPPTLILPIKSMVDKGVLD----------EGYLRKIFPRLK 294 *********************************************************************8888..........479********* PP Glyco_hydro_63 197 awfewfrktqkGkleetyrWrGRdattkrelnpktLasGlDDyPRashpseaelhvDlrcWvalaakvlaelaellgeeedkekyaktekelsdn 291 awf+wf++tq G+l++tyrW+GRd++t++elnpktL+sGlDDyPRashps++e+h+DlrcW+a+aa +a++a+++ge++d+ y++t+++lsdn FUN_000859-T1 295 AWFNWFNTTQLGNLPSTYRWHGRDVNTDKELNPKTLTSGLDDYPRASHPSDDERHMDLRCWMAFAAALMANIADAVGEKSDAFLYRSTSDYLSDN 389 *********************************************************************************************** PP Glyco_hydro_63 292 elldklhwseeekayaDlgvhtekvklkkkev....egqkkelvrvv..eekpelqlvealGYvslfPlllklldadsekleklldlikdpeelw 380 +lldk+hws +++ y+D+g+ht+ vkl +++v +g++k++vr+v ++ p+l++v+a+GYvslfP+ll++ld+ s+klek+l+++kdpe+lw FUN_000859-T1 390 KLLDKYHWSPKAEFYSDYGNHTKLVKLVRRSVqpsqPGSPKKTVRIVtsKQGPSLKFVNAFGYVSLFPFLLHILDPASPKLEKILKDLKDPERLW 484 *****************************999655455559999998656789****************************************** PP Glyco_hydro_63 381 sdyGlrslsksselygkrntehdepYWrgpiWininylilsalkhyskvegpykekakeiykeLranlvnnvvkqyketGfvweqYddetGkgkg 475 s+yGlrslsks+ ly+k+ntehd+pYWrg+iWininyl+++al +y+++ gpy++ ak+iy++Lr+nl+ n++++y+++Gf+weqYdd+ G+gkg FUN_000859-T1 485 SEYGLRSLSKSDFLYQKYNTEHDAPYWRGAIWININYLAVRALDYYASNTGPYQSMAKDIYTDLRSNLISNIFREYQRSGFIWEQYDDIAGNGKG 579 *********************************************************************************************** PP Glyco_hydro_63 476 akpFtGWtslvvlimae 492 ++pFtGW+slvvl+m+e FUN_000859-T1 580 SHPFTGWSSLVVLMMSE 596 ***************96 PP >> MGH1-like_GH Mannosylglycerate hydrolase MGH1-like glycoside hydrolase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.9 0.0 8e-30 4.1e-26 17 354 .. 194 584 .. 182 587 .. 0.82 Alignments for each domain: == domain 1 score: 92.9 bits; conditional E-value: 8e-30 MGH1-like_GH 17 rwl.dprrawde.letlfrgqwadGmvphivfhkdd...................eaagaprg..patsgitqppvaadavrrlyevdg.drafla 88 r + + ++wde ++ l+ +qw+++ +i+ h d + + p+ ++ + pp + ++ +++ d+++l+ FUN_000859-T1 194 RPFfPRGFLWDEgFHQLLISQWDESISKDIIGHWLDliniegwipreqilgdearT--KVPSDfvVQHNENANPPTLILPIKSMVDKGVlDEGYLR 287 55555566666666777777777777777777777777777777777777776433..33333447888899999999999999887669****** PP MGH1-like_GH 89 ellpklvawhrwweeerdsegtGlvwivhpwesGmdnspswdaplarvepasmrptkedydrylrlvragwdpaalaes.frvarptinsyllaaa 183 +++p+l aw++w++++ + l+ ++ G+d + l+ + +++ d+y r+ + + ++ + ++ aa FUN_000859-T1 288 KIFPRLKAWFNWFNTTQLGN---LPSTY-R-WHGRDVNTDK--ELN------PKTLTSGLDDYPRAS----------HPsDDERHMDLRCWMAFAA 360 ****************8877...77775.3.4688866666..333......234555666776662..........222444567888999999* PP MGH1-like_GH 184 raLaaiAellgdtadaaeyraraarlk..aavqerlWdedlgffvdrdlrs................................galirarelagfl 245 a+iA ++g+++da yr++++ l + ++++ W+++++f+ d+ ++ ++++a + ++++ FUN_000859-T1 361 ALMANIADAVGEKSDAFLYRSTSDYLSdnKLLDKYHWSPKAEFYSDYGNHTklvklvrrsvqpsqpgspkktvrivtskqgpsLKFVNAFGYVSLF 456 ************************997225799**************9999********************************************* PP MGH1-like_GH 246 Pllfglpde..akyaaaleqlldeagfaapyglptveprspaFdp......eryWrGpvWpfatwllltgLanlg.........eaedaarlleey 324 P+l+ ++d+ +k +++l++l+d+++++ +ygl++++ ++ +++ yWrG++W+++++l +++L + +++ +++l++ + FUN_000859-T1 457 PFLLHILDPasPKLEKILKDLKDPERLWSEYGLRSLSKSDFLYQKyntehdAPYWRGAIWININYLAVRALDYYAsntgpyqsmAKDIYTDLRSNL 552 ****999776799*************************9988888888*9999*******************************999999999999 PP MGH1-like_GH 325 aa..lvekngesgfaEyfdPdtGaglgsedys 354 + e + + ++E +d G g+gs+ ++ FUN_000859-T1 553 ISniFREYQRSGFIWEQYDDIAGNGKGSHPFT 584 88433333344569***************996 PP >> Trehalase Trehalase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 1.9e-06 0.0099 307 479 .. 350 573 .. 328 597 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 1.9e-06 Trehalase 307 vDLNallyklekdiaefekklgeketsekfeekaearkka..idkvLWneeagvylDYdlkkk................................k 368 +DL ++ + +a++++++gek+ + +++ ++ + ++ +dk+ W+ +a++y DY ++k k FUN_000859-T1 350 MDLRCWMAFAAALMANIADAVGEKSDAFLYRSTSDYLSDNklLDKYHWSPKAEFYSDYGNHTKlvklvrrsvqpsqpgspkktvrivtskqgpslK 445 699999999999*******************999987643339****************99999*************************9999999 PP Trehalase 369 qteyfsatnlvpLwaglaskeqaaklvakvlakleesgllvapgglatsllk......sgeQWDyPn....gWaPlqilavegLeryge.....ee 449 ++f +l+p+ + + + + + +k l++l++ + l ++ gl + + + D+P+ W +lav++L y + ++ FUN_000859-T1 446 FVNAFGYVSLFPFLLHILDPAS--PKLEKILKDLKDPERLWSEYGLRSLSKSdflyqkYNTEHDAPYwrgaIWININYLAVRALDYYASntgpyQS 539 999999999****999999888..789999999999999998766655433222222467889***955545999999******999988899977 PP Trehalase 450 laee....laerwlktvtkafseegklvEKYdvt 479 +a++ l +++ ++++ ++++g + E Yd FUN_000859-T1 540 MAKDiytdLRSNLISNIFREYQRSGFIWEQYDDI 573 776511115678999****************955 PP >> GDE_C Amylo-alpha-1,6-glucosidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 0.95 4.9e+03 224 245 .. 348 369 .. 341 413 .. 0.58 2 ? 13.4 0.1 7.5e-06 0.038 250 362 .. 472 588 .. 453 593 .. 0.66 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 0.95 GDE_C 224 kdlqlRpNflialslapellse 245 + + lR+ +++a +l ++ + FUN_000859-T1 348 RHMDLRCWMAFAAALMANIADA 369 5666666666666666555432 PP == domain 2 score: 13.4 bits; conditional E-value: 7.5e-06 GDE_C 250 kilekae..keLltPlGlktLdpddpkYkgtYegdedsrdaaYHqGtvWvwllgaylrallkveek.......skealeevk.alleglekhlees 335 kil+ + + L + +Gl++L+++d Y+ Y ++++da Y +G++W+ + +ral + +++ k ++ ++ +l++++ + e + FUN_000859-T1 472 KILKDLKdpERLWSEYGLRSLSKSDFLYQK-Y---NTEHDAPYWRGAIWININYLAVRALDYYASNtgpyqsmAKDIYTDLRsNLISNI--FREYQ 561 455544322689999***********9874.4...567899********9888778888777666655543222222333330333322..23334 PP GDE_C 336 algsipElfdgdaeylpkgciaqAWSv 362 g i E +d+ a + + ++ WS+ FUN_000859-T1 562 RSGFIWEQYDDIAGNGKGSHPFTGWSS 588 556778888877777777777777776 PP >> Bac_rhamnosid6H Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 3.8e-05 0.2 116 218 .. 282 401 .. 243 439 .. 0.73 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 3.8e-05 Bac_rhamnosid6H 116 DekilkkqYesmkryldylkqrskd.................glw.elsafqlgDWldpekrdgaektekdlvataylvrslklvakiakllgk 191 De l+k+++ +k+++++ ++++ +l+ + + +l D+ + ++++ e+++ ++++ ++ l+a+ia ++g+ FUN_000859-T1 282 DEGYLRKIFPRLKAWFNWFNTTQLGnlpstyrwhgrdvntdkELNpKTLTSGLDDYPRAS-HPSD--DERHMDLRCWMAFAAALMANIADAVGE 372 778888899999999999888877745555444444444433333344445555555222.3333..34444469******************* PP Bac_rhamnosid6H 192 dedakkyaalaeelka.afnkkyl.eetg 218 + da y++ + l + + +ky ++++ FUN_000859-T1 373 KSDAFLYRSTSDYLSDnKLLDKYHwSPKA 401 ********998887541455555546665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (598 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 488 (0.0191035); expected 510.9 (0.02) Passed bias filter: 454 (0.0177726); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 5754.05 // Query: FUN_000859-T2 [L=837] Description: FUN_000859 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-215 715.3 1.1 6.6e-215 715.0 1.1 1.1 1 Glyco_hydro_63 Glycosyl hydrolase family 63 C-terminal doma 4.6e-46 158.2 0.0 8.2e-46 157.4 0.0 1.4 1 Glyco_hydro_63N Glycosyl hydrolase family 63 N-terminal doma 5.2e-26 92.5 0.0 1e-25 91.6 0.0 1.4 1 MGH1-like_GH Mannosylglycerate hydrolase MGH1-like glycos 0.0096 15.3 0.1 0.02 14.3 0.1 1.5 1 Trehalase Trehalase ------ inclusion threshold ------ 0.029 13.8 0.1 0.065 12.7 0.1 1.6 1 GDE_C Amylo-alpha-1,6-glucosidase 0.098 12.4 0.0 0.35 10.6 0.0 1.9 2 Bac_rhamnosid6H Bacterial alpha-L-rhamnosidase 6 hairpin gly Domain annotation for each model (and alignments): >> Glyco_hydro_63 Glycosyl hydrolase family 63 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 715.0 1.1 1.5e-218 6.6e-215 7 492 .] 357 835 .. 351 835 .. 0.96 Alignments for each domain: == domain 1 score: 715.0 bits; conditional E-value: 1.5e-218 Glyco_hydro_63 7 eeklekkkkefeekfekkFklkekdlekeelklakaalsnllGgigyfyGsslvkresvleedefvkykpaeLftavPsRpfFPRGFlWDeGFhq 101 e+ e +++f++kfe+kF+l++k+++++++++a+aalsn++GgigyfyGss+v s++ + ++v+y++ +L+tavPsRpfFPRGFlWDeGFhq FUN_000859-T2 357 ESLREFYSQQFDRKFEEKFSLTSKGFSEKQVQFAQAALSNMVGGIGYFYGSSKVI--SRFFK-KPVDYWDSPLYTAVPSRPFFPRGFLWDEGFHQ 448 555566789*********************************************9..56644.79****************************** PP Glyco_hydro_63 102 lliskwdsdltleilasWldllnadGWipReqilgaearskvPeefvvqkpeianPPtlllalkklleklklekvsekekeklleflkklyprlk 196 llis+wd +++ +i+++Wldl+n +GWipReqilg+ear+kvP++fvvq++e+anPPtl+l++k++++k l+ +l+k++prlk FUN_000859-T2 449 LLISQWDESISKDIIGHWLDLINIEGWIPREQILGDEARTKVPSDFVVQHNENANPPTLILPIKSMVDKGVLD----------EGYLRKIFPRLK 533 *********************************************************************8888..........479********* PP Glyco_hydro_63 197 awfewfrktqkGkleetyrWrGRdattkrelnpktLasGlDDyPRashpseaelhvDlrcWvalaakvlaelaellgeeedkekyaktekelsdn 291 awf+wf++tq G+l++tyrW+GRd++t++elnpktL+sGlDDyPRashps++e+h+DlrcW+a+aa +a++a+++ge++d+ y++t+++lsdn FUN_000859-T2 534 AWFNWFNTTQLGNLPSTYRWHGRDVNTDKELNPKTLTSGLDDYPRASHPSDDERHMDLRCWMAFAAALMANIADAVGEKSDAFLYRSTSDYLSDN 628 *********************************************************************************************** PP Glyco_hydro_63 292 elldklhwseeekayaDlgvhtekvklkkkev....egqkkelvrvv..eekpelqlvealGYvslfPlllklldadsekleklldlikdpeelw 380 +lldk+hws +++ y+D+g+ht+ vkl +++v +g++k++vr+v ++ p+l++v+a+GYvslfP+ll++ld+ s+klek+l+++kdpe+lw FUN_000859-T2 629 KLLDKYHWSPKAEFYSDYGNHTKLVKLVRRSVqpsqPGSPKKTVRIVtsKQGPSLKFVNAFGYVSLFPFLLHILDPASPKLEKILKDLKDPERLW 723 *****************************999655455559999998656789****************************************** PP Glyco_hydro_63 381 sdyGlrslsksselygkrntehdepYWrgpiWininylilsalkhyskvegpykekakeiykeLranlvnnvvkqyketGfvweqYddetGkgkg 475 s+yGlrslsks+ ly+k+ntehd+pYWrg+iWininyl+++al +y+++ gpy++ ak+iy++Lr+nl+ n++++y+++Gf+weqYdd+ G+gkg FUN_000859-T2 724 SEYGLRSLSKSDFLYQKYNTEHDAPYWRGAIWININYLAVRALDYYASNTGPYQSMAKDIYTDLRSNLISNIFREYQRSGFIWEQYDDIAGNGKG 818 *********************************************************************************************** PP Glyco_hydro_63 476 akpFtGWtslvvlimae 492 ++pFtGW+slvvl+m+e FUN_000859-T2 819 SHPFTGWSSLVVLMMSE 835 ***************96 PP >> Glyco_hydro_63N Glycosyl hydrolase family 63 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 157.4 0.0 1.9e-49 8.2e-46 3 161 .. 113 264 .. 111 294 .. 0.92 Alignments for each domain: == domain 1 score: 157.4 bits; conditional E-value: 1.9e-49 Glyco_hydro_63N 3 lWGpYrpnlYfGlrpRipkslltGlmWfkvddyqsvqkirhtceqndglakygWeeyDgrkgGrqtikDeennldlttsfvKvkdgk.gGsWav 95 +WG Yr+nlYfG+r+R+p+sl+tGlmWf + ++ irh ceq+d+l+kygW ++Dg ++G q+i D++ + l+t+fvK +g+ gG+W++ FUN_000859-T2 113 FWGSYRSNLYFGMRTRSPQSLMTGLMWFPLFSPDGQLAIRHMCEQSDNLRKYGWLKHDGSNFGSQEIVDHD--FVLNTDFVKRLGGNhGGDWTA 204 7**********************************99********************************99..8899*****999999****** PP Glyco_hydro_63N 96 rvkgkpredakkaktsvvfYaglegegsleleneeeeeglegdvklkGeseelgefkleitdgpkt 161 r++gk++ ++++ +s++fYa+ eg+++l+ ++ + +l+G+s+elg+f++ + + pk FUN_000859-T2 205 RISGKEMG-NPTQVVSLLFYATHEGQAQLQPVVNK-----KMPTELHGHSPELGSFTMYFASPPKI 264 *****987.8999************9999988666.....4589***************9997664 PP >> MGH1-like_GH Mannosylglycerate hydrolase MGH1-like glycoside hydrolase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.6 0.0 2.4e-29 1e-25 17 354 .. 433 823 .. 421 826 .. 0.82 Alignments for each domain: == domain 1 score: 91.6 bits; conditional E-value: 2.4e-29 MGH1-like_GH 17 rwl.dprrawde.letlfrgqwadGmvphivfhkdd...................eaagaprg..patsgitqppvaadavrrlyevdg.drafla 88 r + + ++wde ++ l+ +qw+++ +i+ h d + + p+ ++ + pp + ++ +++ d+++l+ FUN_000859-T2 433 RPFfPRGFLWDEgFHQLLISQWDESISKDIIGHWLDliniegwipreqilgdearT--KVPSDfvVQHNENANPPTLILPIKSMVDKGVlDEGYLR 526 55555566666666677777777777777777777777777777777777776433..33333447888899999999999999887669****** PP MGH1-like_GH 89 ellpklvawhrwweeerdsegtGlvwivhpwesGmdnspswdaplarvepasmrptkedydrylrlvragwdpaalaes.frvarptinsyllaaa 183 +++p+l aw++w++++ + l+ ++ G+d + l+ + +++ d+y r+ + + ++ + ++ aa FUN_000859-T2 527 KIFPRLKAWFNWFNTTQLGN---LPSTY-R-WHGRDVNTDK--ELN------PKTLTSGLDDYPRAS----------HPsDDERHMDLRCWMAFAA 599 ****************8877...77775.3.4688866666..333......234555666776662..........222444567888999999* PP MGH1-like_GH 184 raLaaiAellgdtadaaeyraraarlk..aavqerlWdedlgffvdrdlrs................................galirarelagfl 245 a+iA ++g+++da yr++++ l + ++++ W+++++f+ d+ ++ ++++a + ++++ FUN_000859-T2 600 ALMANIADAVGEKSDAFLYRSTSDYLSdnKLLDKYHWSPKAEFYSDYGNHTklvklvrrsvqpsqpgspkktvrivtskqgpsLKFVNAFGYVSLF 695 ************************997225799**************9999********************************************* PP MGH1-like_GH 246 Pllfglpde..akyaaaleqlldeagfaapyglptveprspaFdp......eryWrGpvWpfatwllltgLanlg.........eaedaarlleey 324 P+l+ ++d+ +k +++l++l+d+++++ +ygl++++ ++ +++ yWrG++W+++++l +++L + +++ +++l++ + FUN_000859-T2 696 PFLLHILDPasPKLEKILKDLKDPERLWSEYGLRSLSKSDFLYQKyntehdAPYWRGAIWININYLAVRALDYYAsntgpyqsmAKDIYTDLRSNL 791 ****999776799*************************9988888888*9999*******************************999999999999 PP MGH1-like_GH 325 aa..lvekngesgfaEyfdPdtGaglgsedys 354 + e + + ++E +d G g+gs+ ++ FUN_000859-T2 792 ISniFREYQRSGFIWEQYDDIAGNGKGSHPFT 823 88433333344569***************996 PP >> Trehalase Trehalase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.1 4.7e-06 0.02 307 479 .. 589 812 .. 566 836 .. 0.82 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 4.7e-06 Trehalase 307 vDLNallyklekdiaefekklgeketsekfeekaearkka..idkvLWneeagvylDYdlkkk................................k 368 +DL ++ + +a++++++gek+ + +++ ++ + ++ +dk+ W+ +a++y DY ++k k FUN_000859-T2 589 MDLRCWMAFAAALMANIADAVGEKSDAFLYRSTSDYLSDNklLDKYHWSPKAEFYSDYGNHTKlvklvrrsvqpsqpgspkktvrivtskqgpslK 684 689999999999*******************999987643339****************99999*************************9999999 PP Trehalase 369 qteyfsatnlvpLwaglaskeqaaklvakvlakleesgllvapgglatsllk......sgeQWDyPn....gWaPlqilavegLeryge.....ee 449 ++f +l+p+ + + + + + +k l++l++ + l ++ gl + + + D+P+ W +lav++L y + ++ FUN_000859-T2 685 FVNAFGYVSLFPFLLHILDPAS--PKLEKILKDLKDPERLWSEYGLRSLSKSdflyqkYNTEHDAPYwrgaIWININYLAVRALDYYASntgpyQS 778 999999999***9999999888..789999999999999998766655433222222467889***9555459999999*****999988899977 PP Trehalase 450 laee....laerwlktvtkafseegklvEKYdvt 479 +a++ l +++ ++++ ++++g + E Yd FUN_000859-T2 779 MAKDiytdLRSNLISNIFREYQRSGFIWEQYDDI 812 776511115678999****************955 PP >> GDE_C Amylo-alpha-1,6-glucosidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 1.5e-05 0.065 250 362 .. 711 827 .. 693 832 .. 0.65 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.5e-05 GDE_C 250 kilekae..keLltPlGlktLdpddpkYkgtYegdedsrdaaYHqGtvWvwllgaylrallkveek.......skealeevk.alleglekhlees 335 kil+ + + L + +Gl++L+++d Y+ Y ++++da Y +G++W+ + +ral + +++ k ++ ++ +l++++ + e + FUN_000859-T2 711 KILKDLKdpERLWSEYGLRSLSKSDFLYQK-Y---NTEHDAPYWRGAIWININYLAVRALDYYASNtgpyqsmAKDIYTDLRsNLISNI--FREYQ 800 455444322689999***********9874.4...567899********9888777888777666555543222222333330333322..23334 PP GDE_C 336 algsipElfdgdaeylpkgciaqAWSv 362 g i E +d+ a + + ++ WS+ FUN_000859-T2 801 RSGFIWEQYDDIAGNGKGSHPFTGWSS 827 456777888777777777777777776 PP >> Bac_rhamnosid6H Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 0.95 4.1e+03 147 178 .. 196 226 .. 188 232 .. 0.80 2 ? 10.6 0.0 8.2e-05 0.35 116 218 .. 521 640 .. 485 677 .. 0.72 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 0.95 Bac_rhamnosid6H 147 afqlgDWldpekrdgaektekdlvataylvrs 178 +++ gDW + + + +++++v+ +++ FUN_000859-T2 196 GNHGGDWTARI-SGKEMGNPTQVVSLLFYATH 226 56779***888.58899999999999999865 PP == domain 2 score: 10.6 bits; conditional E-value: 8.2e-05 Bac_rhamnosid6H 116 DekilkkqYesmkryldylkqrskd.................glw.elsafqlgDWldpekrdgaektekdlvataylvrslklvakiakllgk 191 De l+k+++ +k+++++ ++++ +l+ + + +l D+ + ++++ e+++ ++++ ++ l+a+ia ++g+ FUN_000859-T2 521 DEGYLRKIFPRLKAWFNWFNTTQLGnlpstyrwhgrdvntdkELNpKTLTSGLDDYPRAS-HPSD--DERHMDLRCWMAFAAALMANIADAVGE 611 777888888899999988888877745555444444444433333344445555555222.3333..34444469******************* PP Bac_rhamnosid6H 192 dedakkyaalaeelka.afnkkyl.eetg 218 + da y++ + l + + +ky ++++ FUN_000859-T2 612 KSDAFLYRSTSDYLSDnKLLDKYHwSPKA 640 ********998887541445555546655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (837 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 623 (0.0243883); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.41u 0.38s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 7870.73 // Query: FUN_000860-T1 [L=69] Description: FUN_000860 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (69 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 481 (0.0188295); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 702.58 // Query: FUN_000861-T1 [L=623] Description: FUN_000861 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-24 86.3 0.0 9.5e-17 61.9 0.0 2.9 2 Rib_mS39_PPR Small ribosomal subunit protein mS39, PPR 1.1e-22 80.3 16.0 9.7e-07 29.3 0.4 7.4 8 PPR_2 PPR repeat family 3.2e-13 50.1 1.8 0.00027 21.4 0.1 5.9 8 PPR_3 Pentatricopeptide repeat domain 2.6e-11 43.8 1.7 1.2e-05 25.3 0.0 4.4 3 PPR_long Pentacotripeptide-repeat region of PRORP 2.1e-10 41.1 0.3 0.0003 21.2 0.1 5.3 6 TPR_24 Fungal tetratrico peptide repeats 6.6e-09 35.9 15.5 0.049 14.4 0.5 8.8 9 PPR PPR repeat 0.0016 18.6 7.8 0.94 9.7 0.1 6.0 7 PPR_1 PPR repeat ------ inclusion threshold ------ 0.061 13.3 2.0 0.91 9.5 0.1 2.3 2 DUF4003 Protein of unknown function (DUF4003) 0.17 13.2 0.1 1.4 10.3 0.0 2.5 3 PIN_3 PIN domain Domain annotation for each model (and alignments): >> Rib_mS39_PPR Small ribosomal subunit protein mS39, PPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.9 0.0 3.3e-20 9.5e-17 2 128 .. 52 174 .. 51 187 .. 0.93 2 ! 21.1 0.0 1.1e-07 0.0003 157 192 .. 236 271 .. 210 273 .. 0.87 Alignments for each domain: == domain 1 score: 61.9 bits; conditional E-value: 3.3e-20 Rib_mS39_PPR 2 diLkaLasTvkrDpTaphYkfhDDPyLipasnvakrtyalakesGrkaAkwireefaklFqhkeadPeieafvpkkvyteesevteeaLkelikka 97 ++Lk LasTvk p ++ +f++D +L+p s+ ++ ak+sGrkaA+++++ + +F ++ +Pe + +++ ++ +te++L+ ik++ FUN_000861-T1 52 AVLKILASTVKPVPNLSNPEFVEDIFLLPRSKDKQDACLAAKQSGRKAAEFVISRCPGIFPLRKPNPEWIS----GLAKATDSKTESDLQYFIKAT 143 79*****************************************************************9443....34455677899********** PP Rib_mS39_PPR 98 kvsdaievydllkkkgvevseetkqslLell 128 + +ai ++ lk++gvevs +t+ +lL+l FUN_000861-T1 144 DARNAILSFERLKEQGVEVSLDTQNDLLDLT 174 *****************************96 PP == domain 2 score: 21.1 bits; conditional E-value: 1.1e-07 Rib_mS39_PPR 157 krktWkdnelaeklfeeleekepkaYsalirGlaky 192 + W++++ a+++f+++e+k+ k+Y a++ Gl+ky FUN_000861-T1 236 FASEWRKDSYAMEMFHSMENKNGKTYEAMVLGLMKY 271 4678*******************************9 PP >> PPR_2 PPR repeat family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.14 4e+02 10 42 .. 136 168 .. 136 174 .. 0.88 2 ? -0.5 0.2 0.7 2e+03 22 33 .. 246 257 .. 244 259 .. 0.90 3 ! 29.3 0.4 3.4e-10 9.7e-07 5 49 .. 260 304 .. 256 305 .. 0.94 4 ! 11.1 0.1 0.00016 0.46 17 46 .. 311 341 .. 308 343 .. 0.91 5 ! 13.3 0.0 3.3e-05 0.094 18 47 .. 354 383 .. 351 383 .. 0.92 6 ! 15.8 0.0 5.5e-06 0.016 4 49 .. 513 558 .. 510 559 .. 0.93 7 ? -1.5 0.0 1.4 4e+03 18 36 .. 569 587 .. 567 590 .. 0.79 8 ! 13.1 0.2 4e-05 0.11 9 34 .. 595 620 .. 589 622 .. 0.89 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.14 PPR_2 10 ingyckkgkveeAfklfneMkkrgvkPdvyTYt 42 +++++k+ + + A+ f+ k++gv+ + T + FUN_000861-T1 136 LQYFIKATDARNAILSFERLKEQGVEVSLDTQN 168 6899999*******************9988865 PP == domain 2 score: -0.5 bits; conditional E-value: 0.7 PPR_2 22 AfklfneMkkrg 33 A+++f+ M++++ FUN_000861-T1 246 AMEMFHSMENKN 257 99*******997 PP == domain 3 score: 29.3 bits; conditional E-value: 3.4e-10 PPR_2 5 tyNtlingyckkgkveeAfklfneMkkrgvkPdvyTYtilikglc 49 ty ++ g++k + + +A++lfneM++ g + + +TY+ l+++ FUN_000861-T1 260 TYEAMVLGLMKYRCYLDAYDLFNEMRQLGYQASLFTYNLLFRAIS 304 999**************************************9865 PP == domain 4 score: 11.1 bits; conditional E-value: 0.00016 PPR_2 17 gkveeAfklfneMkkrgv.kPdvyTYtilik 46 k+e+A +l ++M ++ v P+ TY+ l+k FUN_000861-T1 311 SKWEKAKELIKNMAEEPVvLPNLKTYNALMK 341 589************97769*********97 PP == domain 5 score: 13.3 bits; conditional E-value: 3.3e-05 PPR_2 18 kveeAfklfneMkkrgvkPdvyTYtilikg 47 + e Af ++++Mk g+ P+ +Y+ li++ FUN_000861-T1 354 RTEIAFGILRDMKAAGLDPTLESYNQLIRA 383 6789************************86 PP == domain 6 score: 15.8 bits; conditional E-value: 5.5e-06 PPR_2 4 vtyNtlingyckkgkveeAfklfneMkkrgvkPdvyTYtilikglc 49 +y++l+n+ + +++ +++++M+k+ ++ +++ t ++k++ FUN_000861-T1 513 HVYTSLFNWAYRTNNPGVVKRFYDDMRKHRIQLTAQVSTAMFKAMG 558 68****************************************9986 PP == domain 7 score: -1.5 bits; conditional E-value: 1.4 PPR_2 18 kveeAfklfneMkkrgvkP 36 +v+ ++++++Mk v+ FUN_000861-T1 569 NVQLMLDVLRWMKVYRVEI 587 5778899******888876 PP == domain 8 score: 13.1 bits; conditional E-value: 4e-05 PPR_2 9 lingyckkgkveeAfklfneMkkrgv 34 li+ +ck+ ++e+A+k ++ k++ v FUN_000861-T1 595 LIRMFCKNDQLEDAWKALDMFKRNRV 620 9****************998888776 PP >> PPR_3 Pentatricopeptide repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.013 37 25 60 .. 139 174 .. 136 177 .. 0.80 2 ! 10.4 0.1 0.00027 0.76 14 61 .. 257 304 .. 249 306 .. 0.90 3 ! 21.4 0.1 9.5e-08 0.00027 2 60 .. 280 343 .. 279 345 .. 0.86 4 ! 14.6 0.0 1.3e-05 0.038 32 58 .. 356 382 .. 350 384 .. 0.91 5 ? -3.6 0.0 6.2 1.8e+04 30 43 .. 451 464 .. 444 465 .. 0.77 6 ? 1.4 0.0 0.17 4.8e+02 18 47 .. 515 544 .. 502 560 .. 0.88 7 ? -0.9 0.1 0.91 2.6e+03 4 36 .. 536 568 .. 533 602 .. 0.63 8 ? -1.8 0.0 1.7 4.7e+03 20 46 .. 594 620 .. 575 621 .. 0.79 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.013 PPR_3 25 yanagnkklalevlermkkkgikPtvvtyNailgvi 60 +++a + + a +er+k++g++ +++t N +l + FUN_000861-T1 139 FIKATDARNAILSFERLKEQGVEVSLDTQNDLLDLT 174 566677788888899*************99999775 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00027 PPR_3 14 dvvtYthLLtayanagnkklalevlermkkkgikPtvvtyNailgvig 61 ++ tY ++ + ++ + + +a +++m++ g + ++ tyN + +i FUN_000861-T1 257 NGKTYEAMVLGLMKYRCYLDAYDLFNEMRQLGYQASLFTYNLLFRAIS 304 6779999999999999999***********************999885 PP == domain 3 score: 21.4 bits; conditional E-value: 9.5e-08 PPR_3 2 ilremerkgikldvvtYthLLtayanag....nkklalevlermkkkg.ikPtvvtyNailgvi 60 +++em + g + ++ tY+ L +a+ + + + + a e ++ m ++ + P++ tyNa++++ FUN_000861-T1 280 LFNEMRQLGYQASLFTYNLLFRAISKSRsfdsKWEKAKELIKNMAEEPvVLPNLKTYNALMKIA 343 799********************9988744446789********8886268**********975 PP == domain 4 score: 14.6 bits; conditional E-value: 1.3e-05 PPR_3 32 klalevlermkkkgikPtvvtyNailg 58 ++a+ +l mk g+ Pt+ +yN ++ FUN_000861-T1 356 EIAFGILRDMKAAGLDPTLESYNQLIR 382 7899*********************97 PP == domain 5 score: -3.6 bits; conditional E-value: 6.2 PPR_3 30 nkklalevlermkk 43 + kla ++++ +k FUN_000861-T1 451 DPKLAIRIFKLFEK 464 67999999998876 PP == domain 6 score: 1.4 bits; conditional E-value: 0.17 PPR_3 18 YthLLtayanagnkklalevlermkkkgik 47 Yt+L + + ++ n + + + m+k +i+ FUN_000861-T1 515 YTSLFNWAYRTNNPGVVKRFYDDMRKHRIQ 544 9**************************997 PP == domain 7 score: -0.9 bits; conditional E-value: 0.91 PPR_3 4 remerkgikldvvtYthLLtayanagnkklale 36 ++m + i+l t++ +a+ +a++ k + FUN_000861-T1 536 DDMRKHRIQLTAQVSTAMFKAMGKAKDPKHIKT 568 566666666666666666666666666555543 PP == domain 8 score: -1.8 bits; conditional E-value: 1.7 PPR_3 20 hLLtayanagnkklalevlermkkkgi 46 L++ + ++ +++a + l+ k +++ FUN_000861-T1 594 LLIRMFCKNDQLEDAWKALDMFKRNRV 620 588999999999999999999999987 PP >> PPR_long Pentacotripeptide-repeat region of PRORP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.0 0.0 0.0016 4.7 10 58 .. 128 176 .. 124 199 .. 0.85 2 ! 25.3 0.0 4.3e-09 1.2e-05 30 133 .. 277 383 .. 270 398 .. 0.81 3 ! 7.0 0.0 0.0017 4.8 33 119 .. 534 619 .. 524 623 .] 0.90 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0016 PPR_long 10 peaelkfklekCskekDlaaAlalydaakaeevrlaayhynvllylcsk 58 +++ + l+ k++D+++A+ +++ k+++v+++ n ll l ++ FUN_000861-T1 128 TDSKTESDLQYFIKATDARNAILSFERLKEQGVEVSLDTQNDLLDLTAQ 176 5677788899999****************************99999854 PP == domain 2 score: 25.3 bits; conditional E-value: 4.3e-09 PPR_long 30 Alalydaakaeevrlaayhynvllylcskaeaaaellklalargfevfermsak.gvspnEatvtslarlaaakrdad......lafalvkeleaa 118 A +l++++ + + + + + yn l +sk+ ++ +++ e ++m + v pn t+ +l+++a+ + ++d af ++++++aa FUN_000861-T1 277 AYDLFNEMRQLGYQASLFTYNLLFRAISKSRSFDS----KWEKAKELIKNMAEEpVVLPNLKTYNALMKIAVVSSETDnmsrteIAFGILRDMKAA 368 77899999999999999999999999999965554....357888888888775257899999999999998888888777777899999999999 PP PPR_long 119 gvaPkLRtysPaLla 133 g++P L +y+ ++ a FUN_000861-T1 369 GLDPTLESYNQLIRA 383 999999999877654 PP == domain 3 score: 7.0 bits; conditional E-value: 0.0017 PPR_long 33 lydaakaeevrlaayhynvllylcskaeaaaellklalargfevfermsakgvspnEatvtslarlaaakrdadlafalvkeleaag 119 yd++ ++ ++l+a+ ++ + ka+++++ +k+ ++ + v++ m+ v+ ++ l+r+ ++ + + a + + ++ FUN_000861-T1 534 FYDDMRKHRIQLTAQVSTAMFKAMGKAKDPKH-IKTNVQLMLDVLRWMKVYRVEITHVHIALLIRMFCKNDQLEDAWKALDMFKRNR 619 6**************************99975.7799********************************999999988877776655 PP >> TPR_24 Fungal tetratrico peptide repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.067 1.9e+02 43 83 .. 136 176 .. 125 191 .. 0.86 2 ! 5.3 0.0 0.0088 25 39 106 .. 261 327 .. 244 355 .. 0.71 3 ? 1.5 0.0 0.13 3.7e+02 52 80 .. 355 383 .. 349 428 .. 0.65 4 ? -3.6 0.0 5 1.4e+04 16 29 .. 451 464 .. 432 467 .. 0.65 5 ? 3.8 0.0 0.025 70 8 85 .. 484 561 .. 481 571 .. 0.84 6 ! 21.2 0.1 1.1e-07 0.0003 16 68 .. 569 621 .. 566 623 .] 0.93 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.067 TPR_24 43 ieafaragdlkeAlrvleimrkagieptkettrpifealkk 83 ++ f++a d ++A+ +e ++++g+e++ +t + ++ + + FUN_000861-T1 136 LQYFIKATDARNAILSFERLKEQGVEVSLDTQNDLLDLTAQ 176 56799***********************9999988876665 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0088 TPR_24 39 fealieafaragdlkeAlrvleimrkagieptkettrpifealkkd...peaidsalealeelkkegkkvd 106 +ea++ ++ +A +++ mr+ g +++ t + +f+a++k+ ++ ++a e+++++++e + FUN_000861-T1 261 YEAMVLGLMKYRCYLDAYDLFNEMRQLGYQASLFTYNLLFRAISKSrsfDSKWEKAKELIKNMAEE----P 327 6777777777777778999999*********************99844434445555555555554....3 PP == domain 3 score: 1.5 bits; conditional E-value: 0.13 TPR_24 52 lkeAlrvleimrkagieptkettrpifea 80 + A+ +l+ m+ ag+ pt e+ +++++a FUN_000861-T1 355 TEIAFGILRDMKAAGLDPTLESYNQLIRA 383 567999*************9999888765 PP == domain 4 score: -3.6 bits; conditional E-value: 5 TPR_24 16 dpaLAtevlrvLsk 29 dp+LA+ ++++++k FUN_000861-T1 451 DPKLAIRIFKLFEK 464 56666666666555 PP == domain 5 score: 3.8 bits; conditional E-value: 0.025 TPR_24 8 LntAarhgdpaLAtevlrvLskrgtklqehhfealieafaragdlkeAlrvleimrkagieptkettrpifealkkdp 85 L+ ++ +d +L + + + ++++ ++h + +l + r+++ r+ + mrk+ i+ t++ +++f+a+ k + FUN_000861-T1 484 LTLTSSDADFSLIYDYYKDIVPQKYRPKDHVYTSLFNWAYRTNNPGVVKRFYDDMRKHRIQLTAQVSTAMFKAMGKAK 561 6677788888899999988889999999999999999888999999999999**********************9853 PP == domain 6 score: 21.2 bits; conditional E-value: 1.1e-07 TPR_24 16 dpaLAtevlrvLskrgtklqehhfealieafaragdlkeAlrvleimrkagie 68 + +L ++vlr ++ +++++++h + li f+++++l++A + l++ +++ ++ FUN_000861-T1 569 NVQLMLDVLRWMKVYRVEITHVHIALLIRMFCKNDQLEDAWKALDMFKRNRVS 621 57899****************************************99998876 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.1 0.27 7.8e+02 19 29 .. 246 256 .. 241 257 .. 0.88 2 ! 14.4 0.5 1.7e-05 0.049 2 30 .. 260 288 .. 259 289 .. 0.95 3 ? 3.2 0.4 0.064 1.8e+02 15 28 .. 312 325 .. 294 328 .. 0.72 4 ? -1.1 0.0 1.5 4.2e+03 2 8 .. 335 341 .. 334 348 .. 0.87 5 ? 0.8 0.0 0.37 1.1e+03 15 30 .. 354 369 .. 351 370 .. 0.84 6 ? -2.0 0.0 3 8.5e+03 2 9 .. 376 383 .. 375 383 .. 0.87 7 ? 4.3 0.0 0.027 77 2 30 .. 514 542 .. 513 543 .. 0.93 8 ? -2.1 0.0 3.1 8.8e+03 4 17 .. 551 564 .. 550 566 .. 0.83 9 ! 11.8 0.1 0.00012 0.34 6 30 .. 595 619 .. 594 620 .. 0.92 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.27 PPR 19 AlelfkeMkek 29 A+e+f+ M+ k FUN_000861-T1 246 AMEMFHSMENK 256 9*******987 PP == domain 2 score: 14.4 bits; conditional E-value: 1.7e-05 PPR 2 tynslIsgycknGkleeAlelfkeMkekG 30 ty +++ g+ k +++ +A +lf+eM++ G FUN_000861-T1 260 TYEAMVLGLMKYRCYLDAYDLFNEMRQLG 288 899***********************998 PP == domain 3 score: 3.2 bits; conditional E-value: 0.064 PPR 15 kleeAlelfkeMke 28 k+e+A+el+k M e FUN_000861-T1 312 KWEKAKELIKNMAE 325 78888888888876 PP == domain 4 score: -1.1 bits; conditional E-value: 1.5 PPR 2 tynslIs 8 tyn+l++ FUN_000861-T1 335 TYNALMK 341 9****97 PP == domain 5 score: 0.8 bits; conditional E-value: 0.37 PPR 15 kleeAlelfkeMkekG 30 + e A+ ++++Mk G FUN_000861-T1 354 RTEIAFGILRDMKAAG 369 56789********988 PP == domain 6 score: -2.0 bits; conditional E-value: 3 PPR 2 tynslIsg 9 +yn lI++ FUN_000861-T1 376 SYNQLIRA 383 8*****96 PP == domain 7 score: 4.3 bits; conditional E-value: 0.027 PPR 2 tynslIsgycknGkleeAlelfkeMkekG 30 +y+sl + + +++ +++++++M+++ FUN_000861-T1 514 VYTSLFNWAYRTNNPGVVKRFYDDMRKHR 542 6*************************986 PP == domain 8 score: -2.1 bits; conditional E-value: 3.1 PPR 4 nslIsgycknGkle 17 +++ ++ +k+ +++ FUN_000861-T1 551 TAMFKAMGKAKDPK 564 78999999999876 PP == domain 9 score: 11.8 bits; conditional E-value: 0.00012 PPR 6 lIsgycknGkleeAlelfkeMkekG 30 lI+ +ckn +le+A + ++ k++ FUN_000861-T1 595 LIRMFCKNDQLEDAWKALDMFKRNR 619 9******************999986 PP >> PPR_1 PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.5 1.2 3.4e+03 26 34 .] 246 254 .. 245 254 .. 0.93 2 ? 3.6 0.1 0.028 78 25 34 .] 276 285 .. 275 285 .. 0.93 3 ? -1.1 0.0 0.84 2.4e+03 2 13 .. 288 299 .. 287 299 .. 0.79 4 ? 1.7 0.0 0.11 3.2e+02 4 14 .. 330 340 .. 329 341 .. 0.85 5 ? -2.9 0.0 2.9 8.3e+03 24 34 .] 356 366 .. 354 366 .. 0.82 6 ? 1.9 0.0 0.096 2.7e+02 2 15 .. 369 382 .. 368 383 .. 0.91 7 ! 9.7 0.1 0.00033 0.94 13 31 .. 595 613 .. 593 614 .. 0.93 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.2 PPR_1 26 AfelldeMe 34 A+e+++ Me FUN_000861-T1 246 AMEMFHSME 254 9*******7 PP == domain 2 score: 3.6 bits; conditional E-value: 0.028 PPR_1 25 eAfelldeMe 34 +A++l++eM+ FUN_000861-T1 276 DAYDLFNEMR 285 8********7 PP == domain 3 score: -1.1 bits; conditional E-value: 0.84 PPR_1 2 GlkPdvvTYntL 13 G++ +TYn L FUN_000861-T1 288 GYQASLFTYNLL 299 667789****76 PP == domain 4 score: 1.7 bits; conditional E-value: 0.11 PPR_1 4 kPdvvTYntLI 14 P+ TYn L FUN_000861-T1 330 LPNLKTYNALM 340 69******995 PP == domain 5 score: -2.9 bits; conditional E-value: 2.9 PPR_1 24 deAfelldeMe 34 + Af +l++M+ FUN_000861-T1 356 EIAFGILRDMK 366 56999*****7 PP == domain 6 score: 1.9 bits; conditional E-value: 0.096 PPR_1 2 GlkPdvvTYntLIn 15 Gl P+ +Yn LI FUN_000861-T1 369 GLDPTLESYNQLIR 382 999*********96 PP == domain 7 score: 9.7 bits; conditional E-value: 0.00033 PPR_1 13 LInGlCkaGrvdeAfelld 31 LI +Ck+ +++A + ld FUN_000861-T1 595 LIRMFCKNDQLEDAWKALD 613 9**************9887 PP >> DUF4003 Protein of unknown function (DUF4003) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.1 0.00032 0.91 82 171 .. 279 365 .. 272 370 .. 0.89 2 ? 3.0 0.2 0.03 86 59 101 .. 477 517 .. 466 557 .. 0.69 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00032 DUF4003 82 dvyekLkeegFkrseYlyLaayillke.kekenrdekiqkakkiykemkknhpfLTssdDyvlavlLAgssenieelleeiEaiYqkLkea 171 d+++++++ g++ s ++y +l+++ + + d+k +kak+ k+m ++ + L + y + +A s +++++ ++E+ + +L++ FUN_000861-T1 279 DLFNEMRQLGYQASLFTY---NLLFRAiSKSRSFDSKWEKAKELIKNMAEEPVVLPNLKTYNALMKIAVVSSETDNM-SRTEIAFGILRDM 365 89**************99...4555555778899*****************************************99.999**99999875 PP == domain 2 score: 3.0 bits; conditional E-value: 0.03 DUF4003 59 lfilaalldleseepeeafrevldvyekLkeegFkrseYlyLa 101 lf++a+ll l s + f + d+y+ ++ ++++ + y + FUN_000861-T1 477 LFYSAFLLTLTS--SDADFSLIYDYYKDIVPQKYRPKDHVYTS 517 799999999888..8899****************877655532 PP >> PIN_3 PIN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.9 5.5e+03 58 98 .. 48 91 .. 37 106 .. 0.56 2 ? 10.3 0.0 0.00048 1.4 63 106 .. 398 447 .. 377 450 .. 0.66 3 ? -3.4 0.0 8.5 2.4e+04 12 34 .. 598 620 .. 594 621 .. 0.72 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.9 PIN_3 58 rkarsveerlllllkva...evvrpdeskalvsklkDpeDakfl 98 r +++v + l +k + + ++++e+ l ++ kD++Da ++ FUN_000861-T1 48 RDPLAVLKILASTVKPVpnlSNPEFVEDIFLLPRSKDKQDACLA 91 44444444433333333555556666666677777888887654 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00048 PIN_3 63 veerlllllkva......evvrpdeskalvsklkDpeDakflelAvaaka 106 +++ l+ + + +v+ + es ++l+DpeDa fl A++a FUN_000861-T1 398 SDDHRLKGNQSVspavlnKVITYLESLPKLPPLRDPEDAFFLRSAMSASL 447 33333333333357777766666677777788**************9865 PP == domain 3 score: -3.4 bits; conditional E-value: 8.5 PIN_3 12 allsrspksasaklldaleegki 34 +++++++ ++++k+ld+ +++++ FUN_000861-T1 598 MFCKNDQLEDAWKALDMFKRNRV 620 55655555899999999999886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (623 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 881 (0.0344882); expected 510.9 (0.02) Passed bias filter: 694 (0.0271677); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.42u 0.36s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 5911.12 // Query: FUN_000862-T1 [L=246] Description: FUN_000862 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-74 249.3 0.0 3.6e-74 249.1 0.0 1.0 1 CutC CutC family ------ inclusion threshold ------ 0.18 12.1 0.0 0.46 10.8 0.0 1.6 1 B12-binding B12 binding domain Domain annotation for each model (and alignments): >> CutC CutC family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 249.1 0.0 2.8e-78 3.6e-74 3 201 .. 1 199 [. 1 200 [. 0.99 Alignments for each domain: == domain 1 score: 249.1 bits; conditional E-value: 2.8e-78 CutC 3 levCidnieslaaalaaGadrveLCaalavgGltPslgllksaakeakipvyvmirPreGdfvysdeelkiileDirtarelglqgvviGaltadg 98 +evCid++es+ +a ++Ga rveLC++l +gG+tPslg+l+ ++++++ipv+vmirPr+Gdf+ysd+e+ +++eDir +e g++g+v+G+l+++g FUN_000862-T1 1 MEVCIDSVESALNAERGGAIRVELCSNLMEGGTTPSLGMLRIIKQRTPIPVFVMIRPRGGDFLYSDDEFYVMKEDIRILKEGGADGIVFGILSSQG 96 69********************************************************************************************** PP CutC 99 eiDlkvleklieaaegLgvtfhrafDlvadpekaleqlvelGvervLtsGqkldalegtdklkeLveqakerisimaGaGvnaenlaelvkatGvn 194 e+D++++++l+e +++L+vtfhrafD+ +dp ++le l++lG++r+LtsGq ++aleg++ + +Lve+akeri i+ G+G+ nl+++++ +G + FUN_000862-T1 97 EVDIERCQELLELSRPLPVTFHRAFDMLKDPFTSLEILIQLGFDRILTSGQDSSALEGLPTISHLVEKAKERIIIVPGGGITERNLERILRGSGAK 192 ************************************************************************************************ PP CutC 195 evhlsak 201 e h sa+ FUN_000862-T1 193 EFHCSAR 199 ****986 PP >> B12-binding B12 binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 3.6e-05 0.46 42 100 .. 129 187 .. 119 195 .. 0.86 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 3.6e-05 B12-binding 42 diveaaeeekpdvvglSalmtttlegakelielakgirprvkvvvGGahptfdpeelle 100 + +e +++ ++d ++ S ++ leg + + +l++++++r+++v GG + + e++l+ FUN_000862-T1 129 TSLEILIQLGFDRILTSGQDSSALEGLPTISHLVEKAKERIIIVPGGGITERNLERILR 187 5678899999***********************99999*********997766666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (246 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 449 (0.0175768); expected 510.9 (0.02) Passed bias filter: 446 (0.0174594); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.42 # Mc/sec: 2387.70 // Query: FUN_000863-T1 [L=332] Description: FUN_000863 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-14 53.5 0.7 8e-08 32.7 0.2 2.9 3 Ank Ankyrin repeat 2.2e-14 54.3 0.1 4e-14 53.4 0.1 1.5 1 Ank_2 Ankyrin repeats (3 copies) 1e-13 51.6 2.9 4.2e-10 40.1 0.5 2.2 2 Ank_4 Ankyrin repeats (many copies) 1.2e-11 44.0 0.3 5.8e-05 23.6 0.1 3.6 3 Ank_3 Ankyrin repeat 2.2e-08 34.8 0.4 2.2e-06 28.4 0.2 2.9 3 Ank_5 Ankyrin repeats (many copies) Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 1.7 8.7e+03 6 30 .. 214 239 .. 212 241 .. 0.60 2 ! 32.7 0.2 1.6e-11 8e-08 2 32 .. 244 274 .. 243 275 .. 0.94 3 ! 18.0 0.0 7.3e-07 0.0037 1 26 [. 276 301 .. 276 304 .. 0.93 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 1.7 Ank 6 LHlAaraghlevvklLL.khGAdvna 30 L A+ + ++ +k LL ++ dvn FUN_000863-T1 214 LFSAITERAYDEAKALLeEQELDVNF 239 55566555566789999443467775 PP == domain 2 score: 32.7 bits; conditional E-value: 1.6e-11 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G++ LH+Aa + +l +v+lLL++GA+vn++d FUN_000863-T1 244 GQSLLHIAAANADLRCVQLLLQYGANVNIKD 274 99*******99**********88******99 PP == domain 3 score: 18.0 bits; conditional E-value: 7.3e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA 26 dG+ PLH+A+ +g+ +++ lL+++GA FUN_000863-T1 276 DGWGPLHAAVTKGNWKCAILLIEAGA 301 7999******99**********8898 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.4 0.1 7.7e-18 4e-14 4 87 .. 217 304 .. 212 307 .. 0.89 Alignments for each domain: == domain 1 score: 53.4 bits; conditional E-value: 7.7e-18 Ank_2 4 AakngnlelvklLl..egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadin 87 A+ + ++ +k Ll ++ d+n++++ g++ Lh+Aa n l +v+lLl++ga+vn d +g+ +Lh A+ +g+ +++ lL+e ga++ FUN_000863-T1 217 AITERAYDEAKALLeeQELDVNFKTPSGQSLLHIAAANADLRCVQLLLQYGANVNikDTDGWGPLHAAVTKGNWKCAILLIEAGAEFG 304 555556678999**877788999999*************************9999999***********************9999875 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.1 2.9e-07 0.0015 1 50 [] 214 264 .. 214 264 .. 0.87 2 ! 40.1 0.5 8.2e-14 4.2e-10 1 50 [] 248 297 .. 248 297 .. 0.98 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 2.9e-07 Ank_4 1 lhaAaksghlellklLlen.gadinat.dgngetaLhfAasngnlevlklLl 50 l++A+ + ++ +k Lle +d+n + +g++ Lh+Aa+n +l++++lLl FUN_000863-T1 214 LFSAITERAYDEAKALLEEqELDVNFKtP-SGQSLLHIAAANADLRCVQLLL 264 678899999999*****543888888856.5********************8 PP == domain 2 score: 40.1 bits; conditional E-value: 8.2e-14 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh Aa+ +l++++lLl++ga++n d +g+ +Lh A+ +gn +++ lL+ FUN_000863-T1 248 LHIAAANADLRCVQLLLQYGANVNIKDTDGWGPLHAAVTKGNWKCAILLI 297 8*********************************************9998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.013 68 3 30 .. 211 238 .. 209 239 .. 0.91 2 ! 23.6 0.1 1.1e-08 5.8e-05 2 31 .] 244 272 .. 243 272 .. 0.96 3 ! 11.4 0.0 0.00011 0.56 1 28 [. 276 302 .. 276 305 .. 0.91 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.013 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 t+L+ A+ ++ +k+Lle++ d+n FUN_000863-T1 211 ITLLFSAITERAYDEAKALLEEQELDVN 238 69***********99******9998887 PP == domain 2 score: 23.6 bits; conditional E-value: 1.1e-08 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+++Lh+Aa n++l v+lLl+ +ga++n+ FUN_000863-T1 244 GQSLLHIAAANADLRCVQLLLQ-YGANVNI 272 99********************.*****96 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00011 Ank_3 1 dgntpLhlAarngrleivklLleklgad 28 dg+ pLh A+ g+ + + lL+e ga+ FUN_000863-T1 276 DGWGPLHAAVTKGNWKCAILLIE-AGAE 302 699*************9999999.8886 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.11 5.4e+02 22 51 .. 216 246 .. 212 247 .. 0.84 2 ! 28.4 0.2 4.3e-10 2.2e-06 2 54 .. 230 282 .. 229 284 .. 0.90 3 ! 5.5 0.1 0.0064 33 19 39 .. 280 300 .. 279 303 .. 0.90 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.11 Ank_5 22 vAakygaleivrlLl.angvdlnlkdeeglt 51 A+ +a++ ++ Ll + d+n k+ +g++ FUN_000863-T1 216 SAITERAYDEAKALLeEQELDVNFKTPSGQS 246 588899*********9999999999998865 PP == domain 2 score: 28.4 bits; conditional E-value: 4.3e-10 Ank_5 2 lengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 le +d+n ++ g+ Lh+Aa + l++v+lLl +g+++n+kd +g+ pl+ FUN_000863-T1 230 LEEQELDVNFKTPSGQSLLHIAAANADLRCVQLLLQYGANVNIKDTDGWGPLH 282 55556889999999**********************************98886 PP == domain 3 score: 5.5 bits; conditional E-value: 0.0064 Ank_5 19 pLhvAakygaleivrlLlang 39 pLh A+ +g++ +++lL++ g FUN_000863-T1 280 PLHAAVTKGNWKCAILLIEAG 300 8****************9666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1038 (0.0406342); expected 510.9 (0.02) Passed bias filter: 671 (0.0262674); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3379.09 // Query: FUN_000864-T1 [L=211] Description: FUN_000864 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.032 14.4 0.6 0.088 13.0 0.3 1.7 2 Oxidoreduct_C Putative oxidoreductase C terminal domain Domain annotation for each model (and alignments): >> Oxidoreduct_C Putative oxidoreductase C terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.3 3.5e-06 0.088 163 268 .. 82 188 .. 73 196 .. 0.80 2 ? 2.3 0.0 0.0062 1.6e+02 119 149 .. 180 210 .. 175 211 .] 0.87 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 3.5e-06 Oxidoreduct_C 163 lrGtkanlvirqgkeekykptlyieplekedkdfeealkkalkklqakypgvelkkle...kgykveipekykvGheahfaqvtekylkylkegkl 255 + k nl i k +++ ly+ + +e+ + +++l++ k ++ y +v++ ++ ++ + +p+ ++ ea + q ++yl+ l +++l FUN_000864-T1 82 TQELKENLAIAYKKLLDFRSPLYMAFSYEEK-QGHAHLAAI-IKDTSYYLNVSIAVMQrlmTERQFPVPSVQSHSSEADLDQFCREYLQALVNNNL 175 556689999999************9988664.555666655.555667777776544422277999****************************** PP Oxidoreduct_C 256 PeWevpnmiakyy 268 + n ++k y FUN_000864-T1 176 ISLVITNDVVKIY 188 9999999999987 PP == domain 2 score: 2.3 bits; conditional E-value: 0.0062 Oxidoreduct_C 119 vkdsllevyanGelnyklkgvhvkvsviWny 149 + ++++++y n + y+l v+v+vs + FUN_000864-T1 180 ITNDVVKIYRNYLIFYTLTAVNVEVSNCISF 210 7899*********************977665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1418 (0.0555099); expected 510.9 (0.02) Passed bias filter: 750 (0.02936); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2083.87 // Query: FUN_000865-T1 [L=213] Description: FUN_000865 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (213 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 819 (0.0320611); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2120.90 // Query: FUN_000866-T1 [L=211] Description: FUN_000866 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.24 11.6 0.0 0.51 10.5 0.0 1.5 1 DUF7437 Family of unknown function (DUF7437) Domain annotation for each model (and alignments): >> DUF7437 Family of unknown function (DUF7437) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 2e-05 0.51 10 41 .. 109 142 .. 108 154 .. 0.88 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 2e-05 DUF7437 10 yverhGvdkLaaAleyaveyvdGevt..eRiaAr 41 y e++G + Laa ++ + +y++G+++ +R++A+ FUN_000866-T1 109 YEEKQGHAHLAALIKDTSNYLNGSISymQRLMAK 142 669********************99866899996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1205 (0.0471717); expected 510.9 (0.02) Passed bias filter: 715 (0.0279898); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2078.17 // Query: FUN_000867-T1 [L=463] Description: FUN_000867 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-50 170.1 0.0 1.2e-49 169.7 0.0 1.1 1 Trypsin Trypsin 9.9e-17 62.4 0.4 2.1e-16 61.3 0.4 1.6 1 CAP Cysteine-rich secretory protein family 0.00014 22.7 0.0 0.00025 21.9 0.0 1.4 1 DUF1986 Domain of unknown function (DUF1986) 0.0004 21.6 0.0 0.00073 20.8 0.0 1.4 1 Trypsin_2 Trypsin-like peptidase domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 169.7 0.0 1.8e-53 1.2e-49 7 220 .] 230 456 .. 225 456 .. 0.93 Alignments for each domain: == domain 1 score: 169.7 bits; conditional E-value: 1.8e-53 Trypsin 7 aqagsfpwqvslqlssg....khfCGGslisenwvlTAaHCvsn....assvkvvlgehnisksegseqklkvekvivhpnynsdtldnDiallkl 94 +++g+fpw +++++ ++ +fC Gsl++++w+lTAaHC+ + +++ +lge + +++g+e +v+kvi hp +++t+d+ ial+kl FUN_000867-T1 230 VTPGKFPWDIAFKYANQfgksNVFCRGSLLDRQWILTAAHCFVVlvnpKFKLEAILGEFDGGNEDGQEVATEVAKVIRHPLHRKNTKDYNIALVKL 325 6899**********99999999*********************99955555555****9999999999999************************* PP Trypsin 95 ksp.vtlgdavrpiclpaassslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsa..yggkvtdnmicagak.ggkdacqGDSGGPlv 185 k+p +++d++rpiclp++s +l+ g+ c v+G+G++++ g + +tl+++n+ ++s +ecr++ + +td+m+c+ ++ + d+c+GDSGGPl FUN_000867-T1 326 KTPlRQFNDYMRPICLPDTSLNLSGGEICAVAGYGYDNSTGkQGKTLRTMNIAILSPNECRRNvlW---LTDSMLCTVYTkRILDTCKGDSGGPLA 418 ***668******************************99999999******************7555...9*********95559************ PP Trypsin 186 csdg...eliGivswgkgcasgnkpgvytrvssyadwi 220 c + +l Givs gk+c++ + p++yt+v+++++wi FUN_000867-T1 419 CYIKgkfYLGGIVSHGKKCSRISSPNIYTNVKYLMPWI 456 *98889*******************************9 PP >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.3 0.4 3.3e-20 2.1e-16 2 118 .. 32 165 .. 31 166 .. 0.85 Alignments for each domain: == domain 1 score: 61.3 bits; conditional E-value: 3.3e-20 CAP 2 dlhNelRaaaglppLswdaeLaaaAqehaktcaeng......shnhrsptggnilarvaaagreniaagees....aedavkgWydepgtynygaa 87 +hN lR+++g++pL w+++La Aq++a+++a n+ ++ +g+ni++ v + ++ag + +++v++Wyde+++y+y + FUN_000867-T1 32 TEHNMLRRQHGAQPLIWSEALAEDAQKWAEYLAINDkiehdtDTLAEKDEGENIAWFVPPQP--KCQAGWKPdcvmCREVVQNWYDEAKNYDYQHG 125 58******************************999977655555555667777777777777..5555555457779****************999 PP CAP 88 ..........hrtnllwpkstkvGcavakcgdgsyvfvvcn 118 h+++++w+ s ++G++ a ++ ++ ++v FUN_000867-T1 126 takhpglpitHFAQVVWNGSMEIGVGSAISKTFGF-IFVAR 165 *****************************999888.77765 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 3.9e-08 0.00025 8 108 .. 247 353 .. 235 359 .. 0.75 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 3.9e-08 DUF1986 8 yleGdlicsGvlidkswvlvsescls.dvdlehsyvsvv...lGgaktkksvkgpyeqivrvda.fkdvpksevvllhlkskvs.fsrhvlPtfvp 97 + + +++c G l+d++w+l c v+ + + +++ Gg+ ++v ++ ++ r +k+ ++ l+ lk++++ f +++P+ +p FUN_000867-T1 247 FGKSNVFCRGSLLDRQWILTAAHCFVvLVNPKFKLEAILgefDGGNEDGQEVATEVAKVIRHPLhRKNTKDYNIALVKLKTPLRqFNDYMRPICLP 342 556799**************9999751566655544443222588899999988888888776516778889**********965999******** PP DUF1986 98 esrnenekdak 108 +++ ++ + FUN_000867-T1 343 DTSLNLSGGEI 353 *9876655544 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 1.1e-07 0.00073 4 136 .. 257 418 .. 253 426 .. 0.59 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 1.1e-07 Trypsin_2 4 fvvssdglvlTnaHvv..............adaeeaavvaekvsvaladgreyaatvvaadp.........elDlallkv.....sedgaglpplp 71 +++ + +lT+aH++ + ++ ++dg+e+a++v + ++++al+k+ + ++ p FUN_000867-T1 257 SLLDRQW-ILTAAHCFvvlvnpkfkleailG----------EFDGGNEDGQEVATEVAKVIRhplhrkntkDYNIALVKLktplrQFNDYMRPICL 341 5555665.********999976555444442..........33444445555555544444344566655688*******8877533333333333 PP Trypsin_2 72 lgdsaplvggervyavGyplggekle....slseGtvsavse.........srderddeell.....qtdaslspGsSGgPlf 136 +++s +l gge + + Gy + +++ + +l++ +++ +s+ d++ l + ++ G SGgPl FUN_000867-T1 342 PDTSLNLSGGEICAVAGY-GYDNSTGkqgkTLRTMNIAILSPnecrrnvlwLTDSM-----LctvytKRILDTCKGDSGGPLA 418 56678*****88888899.3333333445677777777777766654443322223.....244454555677789****996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (463 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 499 (0.0195342); expected 510.9 (0.02) Passed bias filter: 457 (0.01789); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 4694.44 // Query: FUN_000868-T1 [L=250] Description: FUN_000868 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (250 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1219 (0.0477197); expected 510.9 (0.02) Passed bias filter: 757 (0.029634); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2467.25 // Query: FUN_000869-T1 [L=69] Description: FUN_000869 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (69 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 289 (0.0113134); expected 510.9 (0.02) Passed bias filter: 262 (0.0102564); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 702.71 // Query: FUN_000870-T1 [L=364] Description: FUN_000870 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-43 148.0 0.3 2.6e-43 146.8 0.3 1.6 1 MMR_HSR1_Xtn C-terminal region of MMR_HSR1 domain 7.5e-23 81.3 0.0 1.7e-22 80.1 0.0 1.6 1 MMR_HSR1 50S ribosome-binding GTPase 3.8e-20 72.2 0.0 6.6e-20 71.4 0.0 1.4 1 TGS TGS domain 2.9e-10 40.4 0.0 6e-10 39.3 0.0 1.5 1 FeoB_N Ferrous iron transport protein B 0.00066 20.2 0.9 0.82 10.2 0.3 2.3 2 Dynamin_N Dynamin family 0.0063 16.4 0.0 0.014 15.3 0.0 1.6 1 SRPRB Signal recognition particle receptor beta subun ------ inclusion threshold ------ 0.028 15.1 0.1 0.089 13.5 0.2 1.8 2 AAA_28 AAA domain 0.052 13.9 0.2 0.2 12.0 0.0 2.0 2 RsgA_GTPase RsgA GTPase 0.052 13.7 0.0 0.11 12.7 0.0 1.4 1 CheW CheW-like domain 0.053 13.6 0.9 44 4.1 0.0 3.3 3 GTP_EFTU Elongation factor Tu GTP binding domain 0.12 11.9 0.3 0.31 10.5 0.1 1.8 2 MeaB Methylmalonyl Co-A mutase-associated GTPase Mea 0.21 11.4 0.1 0.37 10.6 0.1 1.4 1 AIG1 AIG1 family Domain annotation for each model (and alignments): >> MMR_HSR1_Xtn C-terminal region of MMR_HSR1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 146.8 0.3 1.2e-46 2.6e-43 2 106 .] 185 289 .. 184 289 .. 0.99 Alignments for each domain: == domain 1 score: 146.8 bits; conditional E-value: 1.2e-46 MMR_HSR1_Xtn 2 gGikitstvkltkldeetikailkeykihnadvliredvtvddlidviegnrvYipclyvlNKiDlisleeldelarepeavviSaekelnldeLk 97 gG+++++t++lt+lde+ ++ il+eyki+na+vlired+t+d+lidvi+ nr Y+pclyv+NKiD is+ee+d+lar p++vv+S+e+elnld+L+ FUN_000870-T1 185 GGVAFNATCTLTHLDEKLVQMILHEYKIFNAEVLIREDCTADQLIDVISANRIYMPCLYVYNKIDCISIEEVDRLARLPHSVVVSCEMELNLDYLL 280 9*********************************************************************************************** PP MMR_HSR1_Xtn 98 eeiwekLdL 106 +iwe+L L FUN_000870-T1 281 MQIWEHLAL 289 *******87 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.1 0.0 8e-26 1.7e-22 1 98 [. 64 165 .. 64 180 .. 0.86 Alignments for each domain: == domain 1 score: 80.1 bits; conditional E-value: 8e-26 MMR_HSR1 1 rvaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkgkkielvDtpGliegaseeegleraflaiee.adlillvvd.aeeglte..l 92 rva++G+p+vGKStL+n+lt + + ++y++tT++ + g ++++g +i+l+D+pG+iega++++g ++++ a+++ ad++++++d ++ ++++ l FUN_000870-T1 64 RVALIGFPSVGKSTLLNKLTSTSSVSASYEFTTLTCIPGVVDYNGANIQLLDLPGIIEGAAQGKGRGKQVIAVARtADMVVMMLDsVKGEIQKglL 159 69**********************************************************************99989********73333433114 PP MMR_HSR1 93 deelee 98 ++ele+ FUN_000870-T1 160 EKELED 165 455555 PP >> TGS TGS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.4 0.0 3.1e-23 6.6e-20 2 60 .] 291 363 .. 290 363 .. 0.98 Alignments for each domain: == domain 1 score: 71.4 bits; conditional E-value: 3.1e-23 TGS 2 rvyl.PdGkvvd......lpkgatveDfAyaIhtelakkfiyAkVnG.......qlvgldhpLedgdvveIvt 60 rvy+ ++G+ +d l++gatve++++ Ih++la+ f+yA+V+G q+vg++h+++d+dv++I + FUN_000870-T1 291 RVYTkKRGEPPDfsggliLRRGATVEHVCHVIHRTLADVFKYALVWGtstkyspQRVGINHVMNDEDVIQIMK 363 8**********************************************************************86 PP >> FeoB_N Ferrous iron transport protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.0 2.8e-13 6e-10 2 90 .. 64 151 .. 63 169 .. 0.85 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 2.8e-13 FeoB_N 2 tvalvGnpnvGkttlfnaltgakqkvgNwpGvtvekkegklklkekeielvDlPGiYslsalseeekvardfll.eekpdvvvnvvdatn 90 +val+G p vGk+tl+n+lt +++ + + +t g++++++ +i+l+DlPGi + ++ + +++++ +++d+vv ++d+ + FUN_000870-T1 64 RVALIGFPSVGKSTLLNKLTSTSSVSASYEFTTLTCIPGVVDYNGANIQLLDLPGIIE--GAAQGKGRGKQVIAvARTADMVVMMLDSVK 151 69*****************************************************965..555555555555542778899999999875 PP >> Dynamin_N Dynamin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.3 0.00039 0.82 1 24 [. 65 88 .. 65 101 .. 0.78 2 ! 8.2 0.0 0.0016 3.4 100 137 .. 108 148 .. 103 156 .. 0.83 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00039 Dynamin_N 1 iavvGdqSsGKSsvlnaLlgeeil 24 +a++G S GKS++ln L+ FUN_000870-T1 65 VALIGFPSVGKSTLLNKLTSTSSV 88 7999**************987644 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0016 Dynamin_N 100 vpdltlvDlPGldsvakgdq...elvkeyikkadiilavvs 137 ++ l+DlPG+++ a + + + v ++++ ad+++++++ FUN_000870-T1 108 GANIQLLDLPGIIEGAAQGKgrgKQVIAVARTADMVVMMLD 148 5799**********999999888888888888888888776 PP >> SRPRB Signal recognition particle receptor beta subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 6.4e-06 0.014 5 56 .. 64 119 .. 60 158 .. 0.73 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 6.4e-06 SRPRB 5 tviiaGlsdsGKtslftkLttd.....svrktvtSqepsvalrykgkkltliDfPGh 56 +v ++G GK +l++kLt+ s++ t p + +y+g +++l+D+PG FUN_000870-T1 64 RVALIGFPSVGKSTLLNKLTSTssvsaSYEFTTLTCIPG-VVDYNGANIQLLDLPGI 119 78899***************9865544444455555554.4689***********95 PP >> AAA_28 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.2 4.2e-05 0.089 1 22 [. 64 85 .. 64 99 .. 0.84 2 ? -2.7 0.0 4 8.6e+03 17 57 .. 324 362 .. 322 364 .] 0.77 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 4.2e-05 AAA_28 1 kivltGgestGKTtllkaLaar 22 +++l+G +s GK+tll++L++ FUN_000870-T1 64 RVALIGFPSVGKSTLLNKLTST 85 799****************976 PP == domain 2 score: -2.7 bits; conditional E-value: 4 AAA_28 17 kaLaarfgypvvpEaareileekqaegedalpwvedllafa 57 + La+ f+y v+ + + ++ ++ +++ ed++++ FUN_000870-T1 324 RTLADVFKYALVWGTSTKYSPQRVGINHV-MND-EDVIQIM 362 67999999999999999999999888885.444.5787776 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 9.2e-05 0.2 107 131 .. 63 87 .. 19 96 .. 0.84 2 ? -1.8 0.0 1.6 3.3e+03 55 75 .. 240 259 .. 221 276 .. 0.70 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 9.2e-05 RsgA_GTPase 107 kttvllGqSGvGKStLinallpele 131 ++l+G vGKStL+n+l+++ + FUN_000870-T1 63 ARVALIGFPSVGKSTLLNKLTSTSS 87 567899999***********98754 PP == domain 2 score: -1.8 bits; conditional E-value: 1.6 RsgA_GTPase 55 epvivlnKiDlleeeeeleel 75 + v nKiD+++ ee +++l FUN_000870-T1 240 PCLYVYNKIDCISIEE-VDRL 259 4455779999999888.6554 PP >> CheW CheW-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 4.9e-05 0.11 37 93 .. 99 155 .. 87 165 .. 0.92 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4.9e-05 CheW 37 yvlgvinlRGevlpvidLrellglpptesdeetrvvvvevggqkvGllVdevsgvle 93 ++ gv+++ G + ++dL +++ ++ + + + v+ v +v ++ d+v+g+++ FUN_000870-T1 99 CIPGVVDYNGANIQLLDLPGIIEGAAQGKGRGKQVIAVARTADMVVMMLDSVKGEIQ 155 678**************************99999999999999999*******9986 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.021 44 6 29 .. 65 88 .. 63 96 .. 0.81 2 ? 3.9 0.2 0.024 51 83 105 .. 130 152 .. 88 163 .. 0.71 3 ? 2.2 0.0 0.076 1.6e+02 118 144 .. 235 261 .. 221 322 .. 0.83 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.021 GTP_EFTU 6 igiighvDhGKtTltdrllyktga 29 +++ig GK+Tl+ +l+ +++ FUN_000870-T1 65 VALIGFPSVGKSTLLNKLTSTSSV 88 678888899*********977654 PP == domain 2 score: 3.9 bits; conditional E-value: 0.024 GTP_EFTU 83 vkevirglaqlDgavlvvdaveG 105 k+vi+ ++++D++v+++d+v+G FUN_000870-T1 130 GKQVIAVARTADMVVMMLDSVKG 152 5789999*************999 PP == domain 3 score: 2.2 bits; conditional E-value: 0.076 GTP_EFTU 118 rklgvpiivviNKmDrvdeaelkevve 144 ++ +p + v NK+D ++ +e++++ + FUN_000870-T1 235 NRIYMPCLYVYNKIDCISIEEVDRLAR 261 45557789999******9998888765 PP >> MeaB Methylmalonyl Co-A mutase-associated GTPase MeaB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.1 0.00015 0.31 31 55 .. 61 84 .. 56 109 .. 0.87 2 ? -2.0 0.0 0.94 2e+03 135 159 .. 128 152 .. 98 161 .. 0.69 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00015 MeaB 31 GraqrvGltGvPGaGkstlvealgl 55 G a rv l G+P +Gkstl+++l+ FUN_000870-T1 61 GDA-RVALIGFPSVGKSTLLNKLTS 84 554.789***************986 PP == domain 2 score: -2.0 bits; conditional E-value: 0.94 MeaB 135 GvGqsevdvaevvdtfvllllpgaG 159 G G+ ++va+ +d++v++l + G FUN_000870-T1 128 GRGKQVIAVARTADMVVMMLDSVKG 152 6677777888888877665544433 PP >> AIG1 AIG1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 0.00017 0.37 2 82 .. 64 139 .. 63 156 .. 0.81 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00017 AIG1 2 rivLvGktgnGkSaTgNsilgkkaFesklsaqsvtkkcqkesrtwdgkkinViDTPglfdlsvsaeeiskeivrclllaee 82 r+ L+G +GkS+ N + ++ + + + t +c +g +i+ D Pg+++ ++ + k+++ +a++ FUN_000870-T1 64 RVALIGFPSVGKSTLLNKLTSTSSVSAS--YEFTTLTCIPGVVDYNGANIQLLDLPGIIEGAAQGKGRGKQVIA---VART 139 78899************99888876655..6889999*************************999999998885...3333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (364 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 690 (0.0270112); expected 510.9 (0.02) Passed bias filter: 593 (0.0232139); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3648.76 // Query: FUN_000871-T1 [L=342] Description: FUN_000871 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-29 101.7 1.9 2.8e-29 101.7 0.3 1.9 2 Nse4_C Nse4 C-terminal 1.9e-16 60.4 0.2 1.9e-16 60.4 0.2 1.9 2 Nse4-Nse3_bdg Binding domain of Nse4/EID3 to Nse3-MAGE Domain annotation for each model (and alignments): >> Nse4_C Nse4 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.1 1.2 1.6e+04 41 63 .. 183 206 .. 175 222 .. 0.47 2 ! 101.7 0.3 2.2e-33 2.8e-29 1 89 [] 229 314 .. 229 314 .. 0.89 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.2 Nse4_C 41 glpvi.esveeeeeeeakeeevsk 63 + p i ++v++++ e+ ++e+++ FUN_000871-T1 183 DKPDIsQKVTPSQLEKVEAEGEAT 206 455553233333333333343333 PP == domain 2 score: 101.7 bits; conditional E-value: 2.2e-33 Nse4_C 1 pinlfkfvinpksFaqtVeNlFylSFLvkdgkvklelde.dglpviesveeeeeeeakeeevskkqavlsldmetWkelieafnikepli 89 p+ lf+fvinp+sF++tVeNlF+lSFLv+dg+++++lde +glp ++ e ++eee +++kkq+v++l+++++ke+i++f+i++p+i FUN_000871-T1 229 PVCLFEFVINPHSFSKTVENLFHLSFLVRDGRAEISLDEeNGLPLVSYIEMSTEEE----KTEKKQVVVNLNLAQYKEIIKTFKITKPMI 314 689***********************************879999995544444443....4469*************************8 PP >> Nse4-Nse3_bdg Binding domain of Nse4/EID3 to Nse3-MAGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.4 0.2 1.5e-20 1.9e-16 1 55 [] 73 127 .. 73 128 .. 0.94 2 ? -3.2 1.4 1.1 1.4e+04 43 53 .. 330 340 .. 326 342 .] 0.49 Alignments for each domain: == domain 1 score: 60.4 bits; conditional E-value: 1.5e-20 Nse4-Nse3_bdg 1 DSrlLvlaSdlgaekarnlksggggfDvdeFvsklktfmggnrleageeddddde 55 DSr+Lv aS+lg+++a++l++ ++f d Fv kl+tfmgg++ ++ e+d++de FUN_000871-T1 73 DSRFLVVASNLGSQQAQQLQTHLVTFSHDTFVQKLITFMGGRNIAEVSEEDEEDE 127 9********************************************7777777776 PP == domain 2 score: -3.2 bits; conditional E-value: 1.1 Nse4-Nse3_bdg 43 rleageedddd 53 +++++++ ddd FUN_000871-T1 330 HTNQEDDVDDD 340 55544444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (342 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 987 (0.0386377); expected 510.9 (0.02) Passed bias filter: 540 (0.0211392); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 3389.53 // Query: FUN_000872-T1 [L=356] Description: FUN_000872 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-20 74.4 1.0 1.1e-20 74.4 1.0 2.6 3 WHD_LYAR LYAR family winged helix domain 4.9e-14 52.4 3.1 4.9e-14 52.4 3.1 3.3 3 zf-LYAR LYAR-type C2HC zinc finger ------ inclusion threshold ------ 0.13 13.0 0.8 0.13 13.0 0.8 3.0 3 Zn_ribbon_ACC Acetyl-CoA carboxylase zinc finger domain 0.14 12.6 3.1 0.42 11.1 3.1 1.9 1 zf-C2HC_3 C2HC zinc finger 0.16 12.6 7.8 0.29 11.8 7.8 1.5 1 DUF7479 Domain of unknown function (DUF7479) 0.54 11.0 8.9 2.4 9.0 8.9 2.1 1 C1_4 TFIIH C1-like domain 6.3 8.1 12.8 0.46 11.7 7.4 2.0 2 zf-TRAF TRAF-type zinc finger 9.7 6.8 17.8 1.4 9.6 11.4 2.6 2 IBR IBR domain, a half RING-finger domain Domain annotation for each model (and alignments): >> WHD_LYAR LYAR family winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 1.7 8 2.6e+04 53 53 .. 193 193 .. 175 213 .. 0.52 2 ? -2.5 0.1 3.3 1.1e+04 55 66 .. 268 279 .. 267 280 .. 0.85 3 ! 74.4 1.0 3.3e-24 1.1e-20 3 71 .. 284 355 .. 282 356 .] 0.92 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 8 WHD_LYAR 53 k 53 k FUN_000872-T1 193 K 193 2 PP == domain 2 score: -2.5 bits; conditional E-value: 3.3 WHD_LYAR 55 lnssskfkvegk 66 l++ skf+ eg+ FUN_000872-T1 268 LSKVSKFEAEGN 279 78999**99986 PP == domain 3 score: 74.4 bits; conditional E-value: 3.3e-24 WHD_LYAR 3 kfkwkklikkiLkqapdgelklKkLkkkVlkayse...sgdtsskeellellekKlnssskfkvegkkVkLv 71 fkwk +ik++L++ +++el++K+L+kkVl+++++ ++ s++++ +l++kK++s+++fkv ++ V+Lv FUN_000872-T1 284 TFKWKSVIKAVLRECDGQELPFKRLRKKVLAEFQAcgaNYTNLSENKIRALFDKKVHSNPNFKVRKDIVRLV 355 69*********************************65334559****************************9 PP >> zf-LYAR LYAR-type C2HC zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.8 0.18 5.6e+02 1 19 [. 4 22 .. 4 23 .. 0.91 2 ? -1.6 0.1 1.2 3.7e+03 1 7 [. 24 30 .. 24 31 .. 0.82 3 ! 52.4 3.1 1.5e-17 4.9e-14 1 28 [] 32 59 .. 32 59 .. 0.98 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.18 zf-LYAR 1 ftCiDCsktFdgdeykaHt 19 f+C C+ t + ++++H FUN_000872-T1 4 FCCNACGRTVKKAQVEKHY 22 89999*************6 PP == domain 2 score: -1.6 bits; conditional E-value: 1.2 zf-LYAR 1 ftCiDCs 7 f C DC+ FUN_000872-T1 24 FECRDCN 30 6799**7 PP == domain 3 score: 52.4 bits; conditional E-value: 1.5e-17 zf-LYAR 1 ftCiDCsktFdgdeykaHtsCItEaeKY 28 ++CiDC+++F+g+ey +Ht CI+EaeKY FUN_000872-T1 32 LSCIDCGQDFYGEEYASHTTCISEAEKY 59 79************************** PP >> Zn_ribbon_ACC Acetyl-CoA carboxylase zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.8 4e-05 0.13 4 21 .. 6 23 .. 4 23 .. 0.95 2 ? -0.4 0.3 0.61 1.9e+03 3 10 .. 25 32 .. 24 33 .. 0.84 3 ? -0.8 0.1 0.83 2.6e+03 3 9 .. 33 39 .. 32 45 .. 0.78 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4e-05 Zn_ribbon_ACC 4 CpsCgeliyrkdLernls 21 C++Cg ++ ++++e++++ FUN_000872-T1 6 CNACGRTVKKAQVEKHYQ 23 ****************96 PP == domain 2 score: -0.4 bits; conditional E-value: 0.61 Zn_ribbon_ACC 3 KCpsCgel 10 C C+el FUN_000872-T1 25 ECRDCNEL 32 7*****96 PP == domain 3 score: -0.8 bits; conditional E-value: 0.83 Zn_ribbon_ACC 3 KCpsCge 9 C Cg+ FUN_000872-T1 33 SCIDCGQ 39 5****97 PP >> zf-C2HC_3 C2HC zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 3.1 0.00013 0.42 23 46 .. 3 26 .. 2 27 .. 0.95 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00013 zf-C2HC_3 23 SfvClqCgglvsasRrdeHlayWC 46 Sf C+ Cg v+++ ++H+++ C FUN_000872-T1 3 SFCCNACGRTVKKAQVEKHYQFEC 26 9********************988 PP >> DUF7479 Domain of unknown function (DUF7479) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 7.8 9e-05 0.29 3 49 .. 4 50 .. 2 59 .. 0.90 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 9e-05 DUF7479 3 wiCakCgeelelgkvelsYlgssfevelprCpkCglvlipeelAkgk 49 + C++Cg ++++++ve +Y + ++ + ++C +Cg+ + ee A + FUN_000872-T1 4 FCCNACGRTVKKAQVEKHYQFECRDCNELSCIDCGQDFYGEEYASHT 50 57*************************************99999764 PP >> C1_4 TFIIH C1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 8.9 0.00074 2.4 2 39 .. 6 37 .. 4 49 .. 0.80 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.00074 C1_4 2 CfgCqkkfpklakkkkdeeltssryrCekCkqdFCiDC 39 C +C ++++k++ +k ++C+ C++ CiDC FUN_000872-T1 6 CNACGRTVKKAQVEK------HYQFECRDCNELSCIDC 37 666776666666664......589************** PP >> zf-TRAF TRAF-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 7.4 0.00014 0.46 11 60 .] 4 49 .. 1 49 [. 0.86 2 ? -3.7 0.2 8 2.6e+04 36 43 .. 226 233 .. 221 235 .. 0.52 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00014 zf-TRAF 11 pCpnecckkkilRedlkdHlekdCkkae.vkCkfkevGCkekvkrealqkH 60 +C n c+++ + + ++++H++ +C+ ++ + C C +++ +e++++H FUN_000872-T1 4 FCCNACGRT-VKKAQVEKHYQFECRDCNeLSCID----CGQDFYGEEYASH 49 577999977.****************96156766....9999999999999 PP == domain 2 score: -3.7 bits; conditional E-value: 8 zf-TRAF 36 kaevkCkf 43 k + Ck+ FUN_000872-T1 226 KSKNRCKY 233 33455666 PP >> IBR IBR domain, a half RING-finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 11.4 0.00043 1.4 20 59 .. 4 41 .. 1 52 [. 0.82 2 ? 0.1 0.4 0.38 1.2e+03 41 52 .. 213 231 .. 191 240 .. 0.67 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00043 IBR 20 wCptpdCekiiekeegkkkcnkvtCskCgtefCfkCkeew 59 +C + C++ ++k + +k +++C+ C++ C++C++++ FUN_000872-T1 4 FCC-NACGRTVKKAQV-EKHYQFECRDCNELSCIDCGQDF 41 675.69*****99999.5556689*************986 PP == domain 2 score: 0.1 bits; conditional E-value: 0.38 IBR 41 k.......vtCskCgtefC 52 + ++C++ +++ C FUN_000872-T1 213 DidnaengMQCKEKSKNRC 231 0333444488888777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (356 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2876 (0.112586); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3444.27 // Query: FUN_000873-T1 [L=333] Description: FUN_000873 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-25 88.7 0.2 3.6e-25 87.9 0.2 1.4 1 Glyco_transf_7C N-terminal domain of galactosyltransferase 4.8e-21 75.3 0.2 8.2e-21 74.5 0.2 1.4 1 Glyco_transf_7N N-terminal region of glycosyl transferase gr ------ inclusion threshold ------ 0.077 12.9 0.2 3.4 7.6 0.0 2.2 2 Glyco_tranf_2_2 Glycosyltransferase like family 2 Domain annotation for each model (and alignments): >> Glyco_transf_7C N-terminal domain of galactosyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.9 0.2 4.3e-29 3.6e-25 2 77 .. 184 261 .. 183 262 .. 0.90 Alignments for each domain: == domain 1 score: 87.9 bits; conditional E-value: 4.3e-29 Glyco_transf_7C 2 hlsvaldkfkyklpyeelfGGvlalskedfkkinGfsnkfwgWGgEDddlyaRllesgleverpkk..eigrytmlkh 77 +++v+++ +++k++y++++GG+l++s+++f+k+nG+sn+fwgWG+EDd+ly R++e++l++ r + ++ y ++kh FUN_000873-T1 184 PFHVSAPFLHPKYHYKTFVGGILIMSVAQFEKVNGLSNRFWGWGREDDELYLRMREAKLSIYRHSSkqIKTGYGTFKH 261 68999***********************************************************99754455555666 PP >> Glyco_transf_7N N-terminal region of glycosyl transferase group 7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.5 0.2 9.7e-25 8.2e-21 43 131 .. 90 177 .. 54 180 .. 0.87 Alignments for each domain: == domain 1 score: 74.5 bits; conditional E-value: 9.7e-25 Glyco_transf_7N 43 CkarqkvaiiipyrnreehLkillkylhplLqrqqldyaiyvieqagnetfnrakllnvgflealkeedydClifhdvdlipeddrnlY 131 +++ +++pyr+r e+L ++ ++ + L+ ++++++i++++q++++ fnra llnvgflea + ++ d + +hdvdl+p + +Y FUN_000873-T1 90 SWGPHQLGVVVPYRDRFEELLEFVPHMDSYLNAKKVKHKIFIVNQVDKHRFNRAALLNVGFLEARN-NNCDYIAMHDVDLLPLNKDLYY 177 45668999********************************************************65.55999************98888 PP >> Glyco_tranf_2_2 Glycosyltransferase like family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.0076 65 50 92 .. 122 168 .. 113 175 .. 0.78 2 ? 7.6 0.0 0.0004 3.4 168 206 .. 206 244 .. 198 278 .. 0.84 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.0076 Glyco_tranf_2_2 50 iidlnlqvylkdeddk.ayslaaarNrGaskae...selvlFlDaDc 92 ++ ++++++ ++ dk + aa N G+ +a +++ D+D FUN_000873-T1 122 AKKVKHKIFIVNQVDKhRFNRAALLNVGFLEARnnnCDYIAMHDVDL 168 56788999877777777***********9988611256888888885 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0004 Glyco_tranf_2_2 168 ilinrrallevGGyDEsliGhgaEDfdlllRlakaiksl 206 +++ ++ +v G +++ G g ED +l+lR+ a s+ FUN_000873-T1 206 LIMSVAQFEKVNGLSNRFWGWGREDDELYLRMREAKLSI 244 5556689************************98876665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (333 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 961 (0.0376199); expected 510.9 (0.02) Passed bias filter: 718 (0.0281073); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3204.96 // Query: FUN_000874-T1 [L=333] Description: FUN_000874 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-05 26.6 0.0 2e-05 25.7 0.0 1.5 1 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family ------ inclusion threshold ------ 0.074 13.7 0.0 1.1 9.9 0.0 2.3 1 Lipase_GDSL GDSL-like Lipase/Acylhydrolase Domain annotation for each model (and alignments): >> Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 1.6e-09 2e-05 2 177 .. 96 248 .. 95 249 .. 0.62 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 1.6e-09 Lipase_GDSL_2 2 lGDSiTaGygdtggdrswpgwlarllaerlgadvvnnlgisGattallrllerld.allrlkpdlvvillGtNDlgrgvpparaaannlealvrrl 96 lGDSi + +r p + l+ + + v n+gi+G+t+ + +l r+ + + + +l GtN+l + p++ + a + +++ l FUN_000874-T1 96 LGDSIIK-----NIERFAPKY-FTLFPAST----VLNAGIPGDTV--EAILYRVLhMSFPSTVTCISLLCGTNNLSSHSPAT-ISAT-VMEILFVL 177 7888888.....456777777.66666666....778********..555555553655566699*********86666655.5566.9******* PP Lipase_GDSL_2 97 raaapgarvlglgplpvgpppppdarrlnarlaalneairevaae.egvpfvdladaladddgrlpdlladdglHPnaaGyr 177 r+++p + + + + lp ++ + ++a ++ v +v + dl + l +++ + d lH++ +G++ FUN_000874-T1 178 RQKCPTCVIHLFPNLPRFDQFFS------NVRATNTYIYFHVKNFfPDVLLHDLPSSLYNRN-----VYREDKLHLTKKGND 248 ***99885553333333333333......344444444444444456666666644444443.....333344888888876 PP >> Lipase_GDSL GDSL-like Lipase/Acylhydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 8.4e-05 1.1 44 207 .. 120 253 .. 93 254 .. 0.66 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 8.4e-05 Lipase_GDSL 44 ganfaisGatiedlgiqleqllrlksdvkdqakpdlvtieiGaNDllnalssparskkrleelldelranlpelgarkflvhglgplgctpekcee 139 + n +i+G+t+e+ l r+++ + + + G+N l++ +spa+ + ++e+l lr+++p ++h + l p FUN_000874-T1 120 VLNAGIPGDTVEA------ILYRVLHMS-FPSTVTCISLLCGTNNLSS--HSPATISATVMEILFVLRQKCPT-----CVIHLFPNL---P----- 193 7777777777766......222222222.5555567777778888777..78888888888888888888887.....244444444...4..... PP Lipase_GDSL 140 lynalaeeynerlnelvnslaaaaedanvvlvdi.........ygfedptkpccgigsefwDglHpsekgykavaea 207 r+++++++++a+ ++ +++++ +++ ++ ++++ + + D+lH+++kg+ ++ ++ FUN_000874-T1 194 -----------RFDQFFSNVRAT---NTYIYFHVknffpdvllHDLPSSLYNRNVYRE---DKLHLTKKGNDILTKW 253 ...........777777777777...77777777777777777888888888877665...9********9998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (333 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 687 (0.0268937); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3287.36 // Query: FUN_000875-T1 [L=173] Description: FUN_000875 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-14 54.1 1.3 2.4e-13 50.9 1.3 2.2 1 LRAT Lecithin retinol acyltransferase Domain annotation for each model (and alignments): >> LRAT Lecithin retinol acyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.9 1.3 9.5e-18 2.4e-13 9 119 .. 34 135 .. 10 136 .. 0.80 Alignments for each domain: == domain 1 score: 50.9 bits; conditional E-value: 9.5e-18 LRAT 9 levsRtlyeHhgiyvGdgk.VvHlapesekavsnsasvlsvllkkasVkkesledfaggdklrvneksddkaeplpneeviqrAeelvGe....ve 99 + R++y Hhgiy +++ V H++ ++ +a+ +k++ df +g++ + ++d+ lp +ev++rAee v++ FUN_000875-T1 34 MTLIRQTYYHHGIYDKENMaVYHFTGAD--------------KANAKPQKSDFTDFFAGHTQLYRVVYEDNERCLPVHEVMRRAEEAVNRsstwPG 115 56789*********87664288999555..............3334456777777877777777777777888899999*******7777544557 PP LRAT 100 YsllsnNCEhFvtecryGks 119 Y+l++nNCE F+t++++Gk+ FUN_000875-T1 116 YDLIKNNCESFATYLKTGKA 135 ******************86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (173 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 612 (0.0239577); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1744.01 // Query: FUN_000876-T1 [L=216] Description: FUN_000876 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-50 170.8 0.0 4.1e-50 170.0 0.0 1.3 1 EVE EVE domain ------ inclusion threshold ------ 0.22 11.7 2.3 3.7 7.8 0.1 2.8 3 DUF508 Domain of unknown function (DUF508) Domain annotation for each model (and alignments): >> EVE EVE domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.0 0.0 3.2e-54 4.1e-50 2 145 .. 44 207 .. 43 208 .. 0.94 Alignments for each domain: == domain 1 score: 170.0 bits; conditional E-value: 3.2e-54 EVE 2 yWlmksepde.........ysiddl..kreketgWdgvrnyqarnllr.amkkGDlvlfYhsgekpqaivgiaeVvseaypdptqfdpkskyydpk 85 Wlmksep++ + i+dl +++++ Wdgvrnyqarn++r +mk G l++fYhs++k ++i+gi+e+v+e y d+tqfdpk+++yd++ FUN_000876-T1 44 RWLMKSEPESrfekgvdvkFGIEDLkrEPNQTACWDGVRNYQARNFMRdQMKIGQLAFFYHSNCKDPGIAGIVEIVKESYVDHTQFDPKDPHYDQA 139 6********9999999999******99999****************************************************************** PP EVE 86 stpekprwlrvdvkfvkklkkpltlkelka....ep....eladmkllrkgrlsvfpvteeewelile 145 +++e+p+w++vdvkfv+ +++ ++lkelk+ ++ l++++l++ +rlsv+pvte+e+++i++ FUN_000876-T1 140 AKKENPKWFMVDVKFVRMMNRFISLKELKSlhleHKtsggPLKSLALFTSPRLSVQPVTEDEFKFICS 207 ******************************555512556689************************98 PP >> DUF508 Domain of unknown function (DUF508) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.1 0.00029 3.7 6 58 .. 12 64 .. 3 80 .. 0.71 2 ? 1.6 0.0 0.023 2.9e+02 35 60 .. 135 157 .. 119 183 .. 0.72 3 ? 0.4 0.0 0.052 6.7e+02 68 85 .. 193 210 .. 184 212 .. 0.88 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.00029 DUF508 6 kvvssstsssassavsssktsdssyvslPtyssanlkstrsgkyvtmvhvkfv 58 +++ ++ s + ++ +ssk+ +++ + y+ +ks +++ v+vkf FUN_000876-T1 12 TTSAAKQSKKSKQDNQSSKSENTKALKQVHYTRWLMKSEPESRFEKGVDVKFG 64 334444555555555666666666666669*********************95 PP == domain 2 score: 1.6 bits; conditional E-value: 0.023 DUF508 35 tyssanlkstrsgkyvtmvhvkfvll 60 y++a +k + mv+vkfv + FUN_000876-T1 135 HYDQAAKKE---NPKWFMVDVKFVRM 157 555555554...233479*****954 PP == domain 3 score: 0.4 bits; conditional E-value: 0.052 DUF508 68 rvqstftdefqsdCrled 85 +vq + def+ C led FUN_000876-T1 193 SVQPVTEDEFKFICSLED 210 6899999*********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (216 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1912 (0.0748483); expected 510.9 (0.02) Passed bias filter: 867 (0.0339401); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2105.01 // Query: FUN_000877-T1 [L=219] Description: FUN_000877 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-31 107.2 3.7 6.5e-31 106.5 3.7 1.3 1 Synaptobrevin Synaptobrevin 1.3e-21 76.7 0.1 2.2e-21 76.0 0.1 1.4 1 Longin Regulated-SNARE-like domain 2.5e-05 23.1 0.2 3.4e-05 22.7 0.2 1.2 1 Prominin Prominin ------ inclusion threshold ------ 0.016 15.8 0.1 0.02 15.5 0.1 1.3 1 MCU Mitochondrial calcium uniporter 0.017 15.3 0.1 0.28 11.3 0.1 2.2 2 Herpes_teg_N Herpesvirus tegument protein, N-terminal 0.023 15.5 0.8 0.039 14.7 0.8 1.3 1 Spectrin_Anc-1 Nuclear anchorage protein 1, spectrin-li 0.077 13.4 0.1 0.13 12.6 0.1 1.3 1 DUF2721 Protein of unknown function (DUF2721) 3.9 8.3 5.1 35 5.2 0.0 2.2 2 Flagellin_arch-type Archaeal-type flagellin Domain annotation for each model (and alignments): >> Synaptobrevin Synaptobrevin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.5 3.7 2e-34 6.5e-31 2 81 .] 130 209 .. 129 209 .. 0.98 Alignments for each domain: == domain 1 score: 106.5 bits; conditional E-value: 2e-34 Synaptobrevin 2 lakiqaevdevkdiMteNidkvleRgekldlLvdktenLqesaeqFkkqarklkrkmwwknikliiiiglvvlvliliii 81 ++k++++v ev+d+Mt+Ni+kvleRgekld Lv+k+e+L s++ F+ q+r+l rkmww+n k+ +i+++vvlv+i++i+ FUN_000877-T1 130 ISKVRRQVHEVQDVMTQNIEKVLERGEKLDVLVEKAEELDHSSQVFHAQSRRLHRKMWWQNQKMCLILTFVVLVIIAAIV 209 899*************************************************************************9986 PP >> Longin Regulated-SNARE-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.0 0.1 6.9e-25 2.2e-21 3 83 .. 31 109 .. 29 110 .. 0.89 Alignments for each domain: == domain 1 score: 76.0 bits; conditional E-value: 6.9e-25 Longin 3 tilekip..ntspqkqsyeednytfhyliedgvtylviadksyprrlaFafLeeikkeFlskyga.kaatasalrpyafnkeFd 83 il+kip n +k++y ++y+fh++++dg++yl++ad+++++r ++afLeei+++F ++ + +a ta + y+f ++F+ FUN_000877-T1 31 SILQKIPlhN--DTKCTYVSGSYHFHVIVDDGLIYLCMADEDFGKRQPYAFLEEIRQRFVNSSLKqRAITA---HTYEFRRDFG 109 69****9974..8******888**************************************98876455555...99***99996 PP >> Prominin Prominin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.2 1.1e-08 3.4e-05 352 446 .. 124 216 .. 77 218 .. 0.88 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 1.1e-08 Prominin 352 ekvknqtaevvpdlkkalaqireqiktlakeiprealsavlsdlenterssksfldevekyekyrwliglvvcsllllivvclllgLlcGilGls 446 + ++q+++v +++ ++ + +++i+++ ++ e+l+ ++++ e++ +ss+ f + + ++ w + +c++l+++v++ ++++++GilG s FUN_000877-T1 124 NDETDQISKVRRQVHEVQDVMTQNIEKVLERG--EKLDVLVEKAEELDHSSQVFHAQSRRLHRKMWWQNQKMCLILTFVVLVIIAAIVLGILGAS 216 55567899999999999999999999999999..99*********************************************************76 PP >> MCU Mitochondrial calcium uniporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.1 6.3e-06 0.02 26 102 .. 110 196 .. 53 208 .. 0.76 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6.3e-06 MCU 26 e.............seeakvlldvkklvkaleealnveeeqlkkereleekleelkeelepleekkaeidkkAerrtrrllwvgLallsv 102 + ++e+ ++++v+ v++++++++ ++ +k e ekl+ l e+ e+l + + ++++++r r+++w ++ + FUN_000877-T1 110 QvlssqmalfsdpcNDETDQISKVRRQVHEVQDVMT---QNIEKVLERGEKLDVLVEKAEELDHSSQVFHAQSRRLHRKMWWQNQKMCLI 196 033334444445667778888889998998888884...457788888999*******************************76544433 PP >> Herpes_teg_N Herpesvirus tegument protein, N-terminal conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.063 2e+02 56 108 .. 66 120 .. 53 142 .. 0.68 2 ? 11.3 0.1 8.6e-05 0.28 38 66 .. 144 172 .. 134 201 .. 0.80 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.063 Herpes_teg_N 56 lrtsgrlkvdeyaqlteiP.kv....iitdavaclivrsseiyGllkkvLsrnfngvt 108 ++ ++ +k + ya l+ei ++ +++ a +++ +++ + +G++ Ls + + FUN_000877-T1 66 MADEDFGKRQPYAFLEEIRqRFvnssLKQRAITAHTYEFRRDFGQV---LSSQMALFS 120 56666777777888888887663444567788899999******99...544444433 PP == domain 2 score: 11.3 bits; conditional E-value: 8.6e-05 Herpes_teg_N 38 srealdevLeeGakldallrtsgrlkvde 66 ++++++vLe G+kld+l++++++l+++ FUN_000877-T1 144 MTQNIEKVLERGEKLDVLVEKAEELDHSS 172 4689*********************9973 PP >> Spectrin_Anc-1 Nuclear anchorage protein 1, spectrin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.8 1.2e-05 0.039 16 79 .. 119 182 .. 113 184 .. 0.90 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.2e-05 Spectrin_Anc-1 16 FvkerdeandqLdklrkpLdeieekslrsldeaeedleklkkaseelsklretlkkLqeLseqL 79 F + +++ +dq+ k+r+++ e+++ ++++++++e+ ekl + e+ ++l+ + + + s +L FUN_000877-T1 119 FSDPCNDETDQISKVRRQVHEVQDVMTQNIEKVLERGEKLDVLVEKAEELDHSSQVFHAQSRRL 182 7888999*******************************************99988777766666 PP >> DUF2721 Protein of unknown function (DUF2721) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 4.1e-05 0.13 17 86 .. 143 212 .. 140 217 .. 0.81 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.1e-05 DUF2721 17 altnRllriadriRqLeeeleelkeeeeedeklkreiknLrrRlrlirraillgvlslllvvlvilllfl 86 ++t + ++ +r +L +e+++e +++++ ++++ ++L+r + + ++ + l+ + ++lv+++ ++l + FUN_000877-T1 143 VMTQNIEKVLERGEKLDVLVEKAEELDHSSQVFHAQSRRLHRKMWWQNQKMCLILTFVVLVIIAAIVLGI 212 67777888999999999999999999999***************99988777766666666666665554 PP >> Flagellin_arch-type Archaeal-type flagellin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.011 35 115 145 .. 142 173 .. 90 176 .. 0.74 2 ? 2.6 3.5 0.066 2.1e+02 10 28 .. 198 216 .. 195 219 .] 0.83 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.011 Flagellin_arch-type 115 asvtng.dnvlepgevveieinladglnpste 145 + +t + ++vle+ge++++ ++ a++l+ s++ FUN_000877-T1 142 DVMTQNiEKVLERGEKLDVLVEKAEELDHSSQ 173 222333588*************9888887765 PP == domain 2 score: 2.6 bits; conditional E-value: 0.066 Flagellin_arch-type 10 vfIAfVlVAAvaagvlint 28 f+++V++AA++ g+l + FUN_000877-T1 198 TFVVLVIIAAIVLGILGAS 216 59************98655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1912 (0.0748483); expected 510.9 (0.02) Passed bias filter: 1135 (0.0444314); expected 510.9 (0.02) Passed Vit filter: 128 (0.00501077); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2177.38 // Query: FUN_000878-T1 [L=372] Description: FUN_000878 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (372 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1110 (0.0434527); expected 510.9 (0.02) Passed bias filter: 506 (0.0198082); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3697.69 // Query: FUN_000879-T1 [L=924] Description: FUN_000879 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-122 410.4 16.5 2.3e-122 409.9 16.5 1.2 1 CIP2A_N CIP2A, N-terminal ------ inclusion threshold ------ 1.6 9.7 62.4 0.23 12.4 33.2 3.6 3 APG6_N Apg6 coiled-coil region Domain annotation for each model (and alignments): >> CIP2A_N CIP2A, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 409.9 16.5 1.8e-126 2.3e-122 4 542 .. 24 560 .. 21 562 .. 0.93 Alignments for each domain: == domain 1 score: 409.9 bits; conditional E-value: 1.8e-126 CIP2A_N 4 seanatqllrhlevi....sgqkltrlftsnqiltseclsclvelledpnisaslilsiigllsqlavdietrdclqntynlnsvlagvvcrs..s 93 se n+ +l r+++v+ s k r f +++l +ecls lv ll n+ + li+ + ll +la d+etr++l+ ty+l s la ++ r s FUN_000879-T1 24 SEQNTKDLERQIDVLigitSSGKPLRGFVPKELLPAECLSSLVGLLSASNVKSNLIIKAMVLLFNLANDVETREVLHSTYDLTSTLAALLHRNhlS 119 89999999999998722234467889****************************************************************997446 PP CIP2A_N 94 htdsvflqciqllqkltynvkifysganidelitflidhiqssedelkmpclgllanlcrhnlsvqthiktlsnvksfyrtlitllahssltvvvf 189 + lqc+qll+++ty ki i+eli +l+ iq e +l +pclgll+nlcrhnl +q+h+k+l n+ks+yrtli++l+hs ltv+vf FUN_000879-T1 120 SNEKTTLQCLQLLERVTYGCKITTPSGYIEELIRYLVTNIQLPECDLTIPCLGLLTNLCRHNLPIQAHVKALENIKSLYRTLIAFLSHSNLTVIVF 215 678899****************************************************************************************** PP CIP2A_N 190 alsilssltlneevgeklfharnihqtfqlifnilingdgtltrkysvdllmdllknpkiadyltryehfssclhqvlgllngkdpdssskvlell 285 alsil+sl+l e++geklf ++nihqtfql+f ling+g tr+ svdl++dll pki + l +eh+s l q l ll + + +kv+ell FUN_000879-T1 216 ALSILTSLSLHEQLGEKLFNSKNIHQTFQLVFTFLINGEGPTTRRSSVDLFVDLLVSPKIQQSLLIHEHLSFYLEQTLALLHLHHSEEVAKVFELL 311 ************************************************************************************************ PP CIP2A_N 286 lafcsvtqlrhmltqmmfeqsppgsatlgshtkcleptvallrwlsqpldgsencsvlalelfkeifedvidaancssadrfvtlllptildqlqf 381 l+fc+v+ lr +l + ++ + sh + +l w+ q +d +s+ al+++kei+e+++d + l ++l ql + FUN_000879-T1 312 LTFCAVSGLRSLLCKALLTTANC--QPKESHVNSTYD--IVLYWINQSVDNHLPVSIKALDFIKEIYEELVDGGLMNQWSPPASDL-ISVLTQLLI 402 ***************99976654..455688776554..4689*****************************99887776666555.5799***** PP CIP2A_N 382 teqnldealtrkkceriakaievlltlcgddtlkmhiakilttvkcttlieqqftygkidlgfgtkvadselcklaadvilktldlinklkplvpg 477 ++d ++ +kc +i ka+evl lc dd+lk + l l+e q+ + l +++a s v+l+ ldl+ klk v g FUN_000879-T1 403 PPAEVDGTILGQKCAQINKALEVLSVLCLDDSLKSAVVEDLRLDYWWKLLEYQYQHNT--LATRSRLAVSWSS-EGVCVVLQMLDLLCKLKEDVIG 495 ***************************************************9987765..5666677766544.46679***************** PP CIP2A_N 478 mevsfykilqdprlitplafaltsdnreqvqsglrilleaaplpdfpalvlgesiaannayrqqe 542 +e + lqd rli la al s+ r+ vq lr+l ea+ lpdf a+ lg+ +a+ na r++e FUN_000879-T1 496 LETQLASALQDQRLIPFLARALNSESRDLVQKALRVLREATSLPDFQAIWLGDLLASSNAAREEE 560 **************************************************************987 PP >> APG6_N Apg6 coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 21.2 0.014 1.7e+02 8 102 .. 673 765 .. 672 774 .. 0.62 2 ? 12.4 33.2 1.8e-05 0.23 15 125 .. 760 868 .. 754 872 .. 0.93 3 ? 4.8 17.8 0.0041 52 45 93 .. 830 878 .. 826 911 .. 0.73 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.014 APG6_N 8 dlLleelkkeleeaekerdaYkeflkklekekeseekeeeleelekeleklekeeeelleeLeelekekeeldaelealeeelealdeeeeefwr 102 d L++++ + +++e e+ + ++ l++ ek++e++ e+++el ++ ++++ke e l++ e+l+ +ee ++ a e++++l+ +++ + FUN_000879-T1 673 DRLISQYRCRRAQSEAECAKLMQLLQTTEKKAEKQA--EQINELLQAQKAATKEMEVMLKQNENLKVVEEEHEQLKIAFAEQSQRLETSQRSLMA 765 78999999999****************999977744..677777777777777777666654444444444444444444444444444433333 PP == domain 2 score: 12.4 bits; conditional E-value: 1.8e-05 APG6_N 15 kkeleeaekerdaYkeflkklekekeseekeeeleelekeleklekeeeelleeLeelekekeeldaelealeeelealdeeeeefwreynelqle 110 ++ l +a++e++a ++ + l++++++ +++++ + k+l++le e+++ +++L+e +++++el++ l +++e +++ ++e+ee ++ +l+ e FUN_000879-T1 760 QRSLMAAQDEHKALSDLNEMLRRHNDN--LKSQHDCTTKQLQELETERKKVVQQLKEKDTKCQELRKTLLKQQEDSKQREKENEELQNKNETLRSE 853 7788999*****************666..46999************************************************************** PP APG6_N 111 llefqderdsleaqy 125 l++ ++er++l +++ FUN_000879-T1 854 LSKAEKERKELAHKL 868 **********99887 PP == domain 3 score: 4.8 bits; conditional E-value: 0.0041 APG6_N 45 eeeleelekeleklekeeeelleeLeelekekeeldaelealeeeleal 93 +e+ ++ eke e+l+++ e+l +eL + eke++el+ +l++le +++ FUN_000879-T1 830 QEDSKQREKENEELQNKNETLRSELSKAEKERKELAHKLSSLELICRQN 878 45789999******************************99999655443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (924 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4152 (0.162537); expected 510.9 (0.02) Passed bias filter: 792 (0.0310041); expected 510.9 (0.02) Passed Vit filter: 223 (0.00872969); expected 25.5 (0.001) Passed Fwd filter: 54 (0.00211392); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.72u 0.41s 00:00:01.12 Elapsed: 00:00:00.45 # Mc/sec: 8270.80 // Query: FUN_000880-T1 [L=1320] Description: FUN_000880 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-74 246.5 3.7 3.5e-23 82.6 0.4 3.4 3 F5_F8_type_C F5/8 type C domain 2.6e-43 148.2 2.8 7.1e-22 78.6 0.2 2.9 2 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 1.7e-17 64.3 9.2 0.0001 23.3 0.5 3.9 3 F5_F8_type_C_2 NedA-like, galactose-binding domain 2.6e-17 63.2 44.1 1.5e-06 28.8 7.4 4.3 4 TSP_1 Thrombospondin type 1 domain 5e-13 49.6 36.0 0.00019 22.1 5.0 4.0 4 TSP1_spondin Spondin-like TSP1 domain 8.9e-11 42.4 38.8 7.6e-08 33.0 10.2 4.5 4 TSP1_ADAMTS Thrombospondin type 1 domain 0.00051 20.3 0.5 0.17 12.1 0.3 3.6 2 Pentaxin Pentaxin family 0.007 17.1 32.6 0.49 11.2 1.9 4.5 4 TSP1_CCN CCN3 Nov like TSP1 domain ------ inclusion threshold ------ 0.029 14.4 0.0 0.14 12.2 0.0 2.1 2 CBM_AftD Arabinofuranosyltransferase D, third carbohyd 0.037 14.4 0.2 0.13 12.6 0.0 2.0 2 Beta-prop_TYW4 tRNA wybutosine-synthesizing protein 4, beta- 2.7 8.7 3.9 27 5.5 0.1 3.0 2 YmzC YmzC-like protein 4.7 8.2 12.9 14 6.7 0.6 3.8 3 TSP1_CFP_C CFP-like, C-terminal thrombospondin type 1 do Domain annotation for each model (and alignments): >> F5_F8_type_C F5/8 type C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.6 0.4 1.6e-26 3.5e-23 1 126 [. 61 195 .. 61 196 .. 0.87 2 ! 81.3 0.0 4.2e-26 8.9e-23 1 127 [] 486 620 .. 486 620 .. 0.90 3 ! 81.9 0.3 2.8e-26 5.9e-23 23 127 .] 750 856 .. 721 856 .. 0.87 Alignments for each domain: == domain 1 score: 82.6 bits; conditional E-value: 1.6e-26 F5_F8_type_C 1 qitasssesgeg.paaaald....GnkntaWssssnddkqwlqvdLgkekkitgvvlqgrqdggngrvksykieysddgenWtevkd........e 83 q++asss+++ + p +a+l+ G +++W+s+ d++++l+v+Lg++++++g+ +qg +++v++y ++ys++g++W vkd + FUN_000880-T1 61 QLSASSSYDERHqPYHARLNktvqG-SRGGWCSAFADETEFLEVNLGNKTNVSGISTQGQSMF-DNWVTKYALSYSLNGKHWFMVKDkknsngklK 154 6789999788888999999955433.355***9999999********************9766.***********************999998755 PP F5_F8_type_C 84 kvkgnsdnstpvtntfdkpvkaryvrlvptswnggngialraE 126 +++gn+d++t+vt+ f+ +++ar++r+ p++w+g + ++r E FUN_000880-T1 155 TFTGNKDRNTVVTHWFP-EITARHLRVLPLKWSGL-TNCMRIE 195 55***************.*************9987.5555555 PP == domain 2 score: 81.3 bits; conditional E-value: 4.2e-26 F5_F8_type_C 1 qitasssesgegpaaaald......GnkntaWssssnddkqwlqvdLgkekkitgvvlqgrqdggngrvksykieysddgenWtevkd....ekv. 85 qitass++s++ p +l+ ++taW+++++d+ ++l+vdL++ek+i+gv lqg+ +++v+s+k+ s+dg++++ v++ e FUN_000880-T1 486 QITASSTYSPHKPFYGRLNlvsfydDPQRTAWCADEDDKEPYLTVDLKEEKTISGVALQGASLT-ENYVTSFKLCHSQDGRTFKCVSEnltgE-Sl 579 89*****88888888888888898544599******************************9655.***********************88744.36 PP F5_F8_type_C 86 kgnsdnstpvtntfdkpvkaryvrlvptswnggngialraEl 127 +g d+++++++ +++ ++ryvr++p+sw g i+lr E+ FUN_000880-T1 580 QGSEDKDSVKIHWLERFFDGRYVRFYPLSWYGD-HICLRTEI 620 9****************************9887.8***9996 PP == domain 3 score: 81.9 bits; conditional E-value: 2.8e-26 F5_F8_type_C 23 ntaWssssnddkqwlqvdLgkekkitgvvlqgrqdggngrvksykieysddgenWtevkd...ekv.kgnsdnstpvtntfdkpvkaryvrlvpts 114 +++W+++ d++q+l++dL+k++k+tg+ +qg + +v++y i ys + +Wt++ + +k+ gn d++t++++++++p++aryvr++p++ FUN_000880-T1 750 RGSWCAKVADHSQFLEIDLKKPRKVTGIGTQGQVTD-GRWVSRYGITYSANVMKWTNYTEnnkQKIfVGNDDRKTITVRHLKHPITARYVRIHPLA 844 459*****************************9887.9*************99*******9887779***************************** PP F5_F8_type_C 115 wnggngialraEl 127 w g i++raEl FUN_000880-T1 845 WYGV-HICMRAEL 856 9998.9*****97 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.6 0.2 3.3e-25 7.1e-22 12 151 .] 313 459 .. 300 459 .. 0.84 2 ! 68.9 0.2 3.4e-22 7.1e-19 2 151 .] 1148 1309 .. 1147 1309 .. 0.87 Alignments for each domain: == domain 1 score: 78.6 bits; conditional E-value: 3.3e-25 Laminin_G_3 12 aslttsafTvsaWvkpdsapqssralvs......essgggyelgldsdgqlrftvnggngaeeavtsgasvpagqWtHvavtydg..gtlrlYvnG 99 ++ + a+T++aW+k+ s+ ++++++++ + ++g+y+l++d++ +f+ n ++ ++vts vp +W+Hva+ty++ g++ +Yvn FUN_000880-T1 313 HNKPRVAITIAAWIKLFSVEGTNSLFDTigglnsTHDNGQYHLEIDDGSVRWFHRNENGEIIFNVTSEVIVPSHVWSHVACTYEAklGQADIYVNA 408 3445779**************999999999997333455******875544445555555566*********************54589******* PP Laminin_G_3 100 eevgsstltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeeia 151 + + +++++g+l+++++ + iG +g ++ fdG+ide+ + n aLs+e+i+ FUN_000880-T1 409 KFILRGDGSGDLSQDWQEKAGIGEHKG-ERLFDGQIDEFYMSNEALSQEDIK 459 ***********9999999999***998.8*********************95 PP == domain 2 score: 68.9 bits; conditional E-value: 3.4e-22 Laminin_G_3 2 ggddyvtlpdasl...ttsafTvsaWvkpdsapqssralvs....essgg......gyelgldsdgqlrftvnggngaeeavtsgasvpagqWt 82 g+++ + l+d+++ + ++ Tv++Wv+++ +++ + l+s + gy++++d+++ +f+ n ++ +++ ++ v++++Wt FUN_000880-T1 1148 GKSGDILLEDTTFrgkPRNGVTVALWVNLARTSRGIHSLFStarvM---TigqimgGYHFEIDDGKVRWFHRNRNQIPVFSAITDDIVRPDVWT 1238 5566777777776543489****************99999666652...0345777******998777778888888888999*********** PP Laminin_G_3 83 Hvavtydggt..lrlYvnGeevgsstltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeeia 151 H+ + y+++t +++YvnG++++ s++ g+l++ +g + +G+ g++++ G +d+++i+n+a+ + +i+ FUN_000880-T1 1239 HLIGSYNSTTldAKVYVNGALRAMSNGYGHLDDFWGYKACVGSFDLGGRYLGGFVDDFHIFNYAIEPGQIK 1309 ********9999**************************99**999789*******************9995 PP >> F5_F8_type_C_2 NedA-like, galactose-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.5 4.8e-08 0.0001 11 79 .. 90 157 .. 81 180 .. 0.73 2 ! 23.2 0.0 5.1e-08 0.00011 4 72 .. 510 578 .. 507 604 .. 0.74 3 ! 20.7 1.0 3.1e-07 0.00066 10 90 .] 752 840 .. 744 840 .. 0.76 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 4.8e-08 F5_F8_type_C_2 11 whta.nedpqwlqvDLgssytissvvltnegdccgerlkgykiqvsddgsnwttvatvtngpggntetit 79 w++a +++++ l+v+Lg ++++s + + ++ + + +y +++s +g++w +v++++n +g + +t+t FUN_000880-T1 90 WCSAfADETEFLEVNLGNKTNVSGISTQGQSM-FDNWVTKYALSYSLNGKHWFMVKDKKNSNG-KLKTFT 157 9999889************************6.788889**********77777777765554.333333 PP == domain 2 score: 23.2 bits; conditional E-value: 5.1e-08 F5_F8_type_C_2 4 DGntntrwhta.nedpqwlqvDLgssytissvvltnegdccgerlkgykiqvsddgsnwttvatvtngpg 72 D + t w+++ +++++l+vDL++++tis v l+ ++ +++ + ++k+ s+dg +++ v + +g++ FUN_000880-T1 510 DDPQRTAWCADeDDKEPYLTVDLKEEKTISGVALQGASL-TENYVTSFKLCHSQDGRTFKCVSENLTGES 578 555669*****777************************7.78888**********866665555424444 PP == domain 3 score: 20.7 bits; conditional E-value: 3.1e-07 F5_F8_type_C_2 10 rwhta.nedpqwlqvDLgssytissvvltnegdccgerlkgykiqvsddgsnwttvatvtngpg.......gntetitf.navtaryvrv 90 w+++ ++ +q l++DL+++++++ + + + g ++ y i +s + +wt++ + ++++ ++++ ++ ++taryvr+ FUN_000880-T1 752 SWCAKvADHSQFLEIDLKKPRKVTGIGTQGQVT-DGRWVSRYGITYSANVMKWTNYTENNKQKIfvgnddrKTITVRHLkHPITARYVRI 840 59999999************************5.7778899*********55555554432222233334245555556789*******7 PP >> TSP_1 Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 1.3 2.8e+03 10 17 .. 291 298 .. 291 300 .. 0.83 2 ! 19.9 8.9 4.1e-07 0.00086 3 49 .] 653 703 .. 651 703 .. 0.83 3 ! 28.5 8.0 8.6e-10 1.8e-06 2 49 .] 1007 1051 .. 1006 1051 .. 0.85 4 ! 28.8 7.4 7.1e-10 1.5e-06 3 42 .. 1058 1092 .. 1057 1101 .. 0.75 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.3 TSP_1 10 svTCgkGi 17 s TCg+G+ FUN_000880-T1 291 SETCGNGV 298 67*****8 PP == domain 2 score: 19.9 bits; conditional E-value: 4.1e-07 TSP_1 3 wseWspCsvTCgkGirvRqRtcksp.qkggepCt...geaqeteaCkmkkC 49 w +Csv+CgkG++ R c+ + ++ +++C+ + ++ +C+++ C FUN_000880-T1 653 WASFGECSVSCGKGTKKRVVKCQPKgNERNQNCPpgtESYTQRIPCTKPSC 703 9999*******************9999999999622144455778999998 PP == domain 3 score: 28.5 bits; conditional E-value: 8.6e-10 TSP_1 2 pwseWspCsvTCgkGirvRqRtckspqkggepCtgeaqete..aCkmkkC 49 +w+ s+CsvTCg+Gi+ R+R c + Ct++ et+ +C+ C FUN_000880-T1 1007 QWGAFSKCSVTCGEGIMKRYRKCGVE-----ECTAPGLETQvvPCSRSSC 1051 7***********************88.....8999988877335877777 PP == domain 4 score: 28.8 bits; conditional E-value: 7.1e-10 TSP_1 3 wseWspCsvTCgkGirvRqRtckspqkggepCtgeaqete 42 ws s+CsvTCg G+r+R+R+c++ +C+ +e+e FUN_000880-T1 1058 WSFYSSCSVTCGVGKRTRSRMCNGV-----SCPKSGSEFE 1092 9**********************66.....6666665544 PP >> TSP1_spondin Spondin-like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 9.9 2.1e+04 13 20 .. 291 298 .. 291 301 .. 0.84 2 ! 19.9 7.3 4.5e-07 0.00097 5 52 .] 652 703 .. 650 703 .. 0.89 3 ! 21.6 4.9 1.3e-07 0.00028 3 52 .] 1005 1051 .. 1004 1051 .. 0.72 4 ! 22.1 5.0 9.1e-08 0.00019 5 52 .] 1057 1101 .. 1055 1101 .. 0.88 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 9.9 TSP1_spondin 13 sktCgkGv 20 s+tCg+Gv FUN_000880-T1 291 SETCGNGV 298 789***98 PP == domain 2 score: 19.9 bits; conditional E-value: 4.5e-07 TSP1_spondin 5 eWseWseCsktCgkGvqtRtRevivepqnggkpCpell....errkCneepC 52 +W +++eCs++CgkG+++R + + + ++ ++Cp + +r +C +++C FUN_000880-T1 652 AWASFGECSVSCGKGTKKRVVKCQPKGNERNQNCPPGTesytQRIPCTKPSC 703 6****************99999999999999****87656778999999999 PP == domain 3 score: 21.6 bits; conditional E-value: 1.3e-07 TSP1_spondin 3 vseWseWseCsktCgkGvqtRtRevivepqnggkpC..pell.errkCneepC 52 +++W+++s+Cs+tCg+G+++R+R+ v ++C p l+ + +C++ +C FUN_000880-T1 1005 LQQWGAFSKCSVTCGEGIMKRYRKCGV------EECtaPGLEtQVVPCSRSSC 1051 689********************9844......44411333346666666666 PP == domain 4 score: 22.1 bits; conditional E-value: 9.1e-08 TSP1_spondin 5 eWseWseCsktCgkGvqtRtRevivepqnggkpCpell...errkCneepC 52 +Ws +s+Cs+tCg G++tR+R+ +g +Cp++ e+ +C + C FUN_000880-T1 1057 QWSFYSSCSVTCGVGKRTRSRMC------NGVSCPKSGsefETISCVLPGC 1101 7*********************9......9999999866678888888777 PP >> TSP1_ADAMTS Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.9 4.1e+03 10 17 .. 291 298 .. 289 300 .. 0.88 2 ! 33.0 10.2 3.6e-11 7.6e-08 5 55 .] 655 703 .. 652 703 .. 0.95 3 ! 10.8 6.4 0.00031 0.65 3 27 .. 1008 1032 .. 1007 1052 .. 0.75 4 ! 10.5 4.0 0.00037 0.79 6 25 .. 1061 1080 .. 1056 1097 .. 0.85 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.9 TSP1_ADAMTS 10 sktCGgGv 17 s+tCG+Gv FUN_000880-T1 291 SETCGNGV 298 89*****8 PP == domain 2 score: 33.0 bits; conditional E-value: 3.6e-11 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsa.qkkPsetqsCnlkpC 55 +++eCs++CG+G+++R v+C+ k+++ ++++C + +++++++ +C++++C FUN_000880-T1 655 SFGECSVSCGKGTKKRVVKCQPKGNE---RNQNCPPgTESYTQRIPCTKPSC 703 79*********************888...88*****9**************9 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00031 TSP1_ADAMTS 3 agkWseCsktCGgGvqtRkvqCvqk 27 g +s+Cs+tCG+G+ +R +C + FUN_000880-T1 1008 WGAFSKCSVTCGEGIMKRYRKCGVE 1032 589***************9999654 PP == domain 4 score: 10.5 bits; conditional E-value: 0.00037 TSP1_ADAMTS 6 WseCsktCGgGvqtRkvqCv 25 +s+Cs+tCG G +tR+ C FUN_000880-T1 1061 YSSCSVTCGVGKRTRSRMCN 1080 78*************99996 PP >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.1 0.3 7.9e-05 0.17 77 173 .. 376 468 .. 361 474 .. 0.74 2 ? 3.1 0.0 0.043 92 77 108 .. 1226 1260 .. 1157 1316 .. 0.54 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 7.9e-05 Pentaxin 77 kvseeav....epvhiCasWesssGivelwvdGkplvkkslkkgytvgaeasiilGqe.qDsyG.GkfdksqslvGelsdlnlWdyvLspeeiktv 166 +v+ e + + h+ ++e+ G ++++v+ k + + + q+ q+ G G+ + ++ + G++ + ++ + +Ls+e+ik++ FUN_000880-T1 376 NVTSEVIvpshVWSHVACTYEAKLGQADIYVNAKFILRGDGSGDL----------SQDwQEKAGiGEHKGERLFDGQIDEFYMSNEALSQEDIKKL 461 44444333433799999***************9766654444333..........33324444447889999***********************9 PP Pentaxin 167 ykgatls 173 ++ ++ FUN_000880-T1 462 MQRCEFE 468 9987766 PP == domain 2 score: 3.1 bits; conditional E-value: 0.043 Pentaxin 77 kvseeav...epvhiCasWesssGivelwvdGkpl 108 ++ v ++h+ s++s++ ++++v+G + FUN_000880-T1 1226 AITDDIVrpdVWTHLIGSYNSTTLDAKVYVNGALR 1260 33333334557899999999999999999999543 PP >> TSP1_CCN CCN3 Nov like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.87 1.8e+03 12 19 .. 291 298 .. 289 300 .. 0.89 2 ! 11.2 1.9 0.00023 0.49 9 37 .. 657 681 .. 651 691 .. 0.78 3 ! 9.8 5.9 0.00064 1.4 6 31 .. 1009 1035 .. 1005 1051 .. 0.77 4 ? 5.8 8.8 0.011 24 7 25 .. 1060 1078 .. 1051 1090 .. 0.74 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.87 TSP1_CCN 12 SktCGlGv 19 S+tCG Gv FUN_000880-T1 291 SETCGNGV 298 89*****8 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00023 TSP1_CCN 9 saCSktCGlGvstRvsndneeCkleketr 37 +CS +CG G++ Rv +C+++ ++r FUN_000880-T1 657 GECSVSCGKGTKKRVV----KCQPKGNER 681 68*************8....666655544 PP == domain 3 score: 9.8 bits; conditional E-value: 0.00064 TSP1_CCN 6 teWsaCSktCGlGvstRvsn.dneeCk 31 + s+CS tCG G+ R+++ eeC+ FUN_000880-T1 1009 GAFSKCSVTCGEGIMKRYRKcGVEECT 1035 6779**************853667775 PP == domain 4 score: 5.8 bits; conditional E-value: 0.011 TSP1_CCN 7 eWsaCSktCGlGvstRvsn 25 s+CS tCG+G tR + FUN_000880-T1 1060 FYSSCSVTCGVGKRTRSRM 1078 3479***********9874 PP >> CBM_AftD Arabinofuranosyltransferase D, third carbohydrate binding module # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 6.5e-05 0.14 23 64 .. 509 546 .. 504 553 .. 0.88 2 ? -2.5 0.0 2.3 4.9e+03 31 59 .. 753 777 .. 749 781 .. 0.72 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 6.5e-05 CBM_AftD 23 tDGDprTaWtApqesvqkktkPtltleLpeptevtglrltps 64 D +rTaW A++ ++++P lt++L e+++++g+ l+ + FUN_000880-T1 509 YDDPQRTAWCADE----DDKEPYLTVDLKEEKTISGVALQGA 546 57889*******9....5699****************99755 PP == domain 2 score: -2.5 bits; conditional E-value: 2.3 CBM_AftD 31 WtApqesvqkktkPtltleLpeptevtgl 59 W A+ ++++ l+++L +p++vtg+ FUN_000880-T1 753 WCAKV----ADHSQFLEIDLKKPRKVTGI 777 55544....234457999********997 PP >> Beta-prop_TYW4 tRNA wybutosine-synthesizing protein 4, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 3.7 7.9e+03 129 150 .. 795 816 .. 747 840 .. 0.48 2 ? 12.6 0.0 6.2e-05 0.13 138 229 .. 893 986 .. 847 993 .. 0.80 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 3.7 Beta-prop_TYW4 129 lvsdkllvweldveestepitv 150 + s ++++w+ +e+++++i v FUN_000880-T1 795 TYSANVMKWTNYTENNKQKIFV 816 3445555555555554444433 PP == domain 2 score: 12.6 bits; conditional E-value: 6.2e-05 Beta-prop_TYW4 138 eldveestepitvv..kklehpllarfGakvvqlesekllivGGvskdellkqeteivaldlesetlksieisekiweekrpllvgfslvstse 229 +l++++ ++p++ +k +++ll+ +G k v+++ + +l+ ++ ++++t +v l ++ +++++ei+++++ + +pl v +s++ +++ FUN_000880-T1 893 SLEKTQGKSPFIELspNKSKQRLLHIVGNKKVHHDASDVLVAPQNKQKAPFHSQTHVVNLTDQNYNFHVLEIPQHVHPNLPPLGVAVSATLNRQ 986 3333444455443311567899*************************************************************99999876655 PP >> YmzC YmzC-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.013 27 22 52 .. 132 165 .. 120 167 .. 0.83 2 ? 3.4 0.0 0.056 1.2e+02 3 21 .. 867 885 .. 865 892 .. 0.87 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.013 YmzC 22 sftlvgdHtfvykDe...snyIKIykydedrNEv 52 s++l g H f kD+ +++K + ++drN v FUN_000880-T1 132 SYSLNGKHWFMVKDKknsNGKLKTFTGNKDRNTV 165 78899*********72223689**********87 PP == domain 2 score: 3.4 bits; conditional E-value: 0.056 YmzC 3 dtviiTDnsnsdyetlqts 21 ++v++TDn s++++ ++ FUN_000880-T1 867 KPVEVTDNEVSSFKMTESG 885 89***********998765 PP >> TSP1_CFP_C CFP-like, C-terminal thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.6 0.0067 14 6 33 .. 651 677 .. 648 686 .. 0.85 2 ? 2.3 0.2 0.15 3.2e+02 7 32 .. 1007 1031 .. 1002 1045 .. 0.82 3 ? 5.0 1.1 0.022 46 7 32 .. 1057 1081 .. 1053 1097 .. 0.84 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0067 TSP1_CFP_C 6 sewsawGlctPpcgpnptrtrqrkckae 33 w+++G c +cg + t+ r kc+++ FUN_000880-T1 651 VAWASFGECSVSCGKG-TKKRVVKCQPK 677 57************87.677999**997 PP == domain 2 score: 2.3 bits; conditional E-value: 0.15 TSP1_CFP_C 7 ewsawGlctPpcgpnptrtrqrkcka 32 +w a+ c +cg + + r rkc FUN_000880-T1 1007 QWGAFSKCSVTCGEGIM-KRYRKCGV 1031 799**********8765.59999965 PP == domain 3 score: 5.0 bits; conditional E-value: 0.022 TSP1_CFP_C 7 ewsawGlctPpcgpnptrtrqrkcka 32 +ws + c +cg + +rtr r c+ FUN_000880-T1 1057 QWSFYSSCSVTCGVG-KRTRSRMCNG 1081 7************86.79******85 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1320 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 861 (0.0337052); expected 510.9 (0.02) Passed bias filter: 622 (0.0243492); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.52u 0.36s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 12480.52 // Query: FUN_000881-T1 [L=151] Description: FUN_000881 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-21 76.3 0.2 5e-21 76.1 0.2 1.1 1 PLAT PLAT/LH2 domain ------ inclusion threshold ------ 0.17 11.8 0.1 0.38 10.7 0.1 1.6 1 DUF7755 Domain of unknown function (DUF7755) Domain annotation for each model (and alignments): >> PLAT PLAT/LH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.1 0.2 3.9e-25 5e-21 4 106 .. 27 125 .. 24 134 .. 0.88 Alignments for each domain: == domain 1 score: 76.1 bits; conditional E-value: 3.9e-25 PLAT 4 kvvtgdkkgagtdadvyislygkvgksaqleltldtsgpdfergaedsfevdtdwdlGallkinlhwdnkgisdewflksitvekpgetgkkvtFp 99 tg+k gagtda v i l+g++g+s+++el+ +dfe+g++d+f ++ + dlG+l+ in+++dn+ + wfl+++++ kp ++g+ ++Fp FUN_000881-T1 27 ITYTGSKFGAGTDARVFIILFGEKGRSKEIELES-KGRNDFEKGQKDTFFIQAK-DLGRLTAINIRHDNSWFGSGWFLEKVRI-KP-TDGCVYEFP 118 455************************7777777.899**************88.7************98779**********.68.67******* PP PLAT 100 cnsWvyg 106 ++W+ + FUN_000881-T1 119 NHKWLAS 125 *****87 PP >> DUF7755 Domain of unknown function (DUF7755) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.1 2.9e-05 0.38 53 90 .. 56 93 .. 22 114 .. 0.80 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 2.9e-05 DUF7755 53 edkkesellhFqrGsvdeftFeGpklgkiealWigles 90 + +++ F++G d+f+ + +lg+++a+ i ++ FUN_000881-T1 56 IELESKGRNDFEKGQKDTFFIQAKDLGRLTAINIRHDN 93 3456677889**********************997764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (151 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 427 (0.0167156); expected 510.9 (0.02) Passed bias filter: 405 (0.0158544); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1496.98 // Query: FUN_000882-T1 [L=97] Description: FUN_000882 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.083 13.4 0.1 0.15 12.6 0.1 1.3 1 DUF4500 Domain of unknown function (DUF4500) 0.086 13.6 0.0 0.1 13.4 0.0 1.2 1 Viral_Rep Putative viral replication protein 0.19 12.0 0.4 0.28 11.4 0.4 1.3 1 DUF4748 Domain of unknown function (DUF4748) Domain annotation for each model (and alignments): >> DUF4500 Domain of unknown function (DUF4500) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 1.7e-05 0.15 47 79 .. 53 85 .. 43 86 .. 0.94 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.7e-05 DUF4500 47 vgYiaYlrakkenkgyyeavdsdgkeelkkkks 79 ++Yi Y +++ +n +y++ v + +ee+ ++ks FUN_000882-T1 53 LSYIKYSKEQVNNGRYHKLVPQKRREEVSRRKS 85 68*****************************98 PP >> Viral_Rep Putative viral replication protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 1.2e-05 0.1 14 64 .. 44 90 .. 24 95 .. 0.83 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 1.2e-05 Viral_Rep 14 llllvlrdelkYlvyqdErgdeGtkHlqGfvefkkrtsLkqlkklfpgraH 64 ++l + +el Y+ y +E++++G+ H v k+r ++ k l++ H FUN_000882-T1 44 FTLKPGSEELSYIKYSKEQVNNGRYHK--LVPQKRREEVSRRKSLLEA--H 90 6777889*****************996..6888888888888877764..4 PP >> DUF4748 Domain of unknown function (DUF4748) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.4 3.3e-05 0.28 22 43 .. 58 79 .. 53 85 .. 0.78 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 3.3e-05 DUF4748 22 fAKrsidadRaarleaerkrmr 43 ++K ++++ R+ +l +++r + FUN_000882-T1 58 YSKEQVNNGRYHKLVPQKRREE 79 9*************99555543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (97 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 626 (0.0245058); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1009.35 // Query: FUN_000883-T1 [L=1674] Description: FUN_000883 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-16 61.1 0.1 6.6e-16 59.6 0.1 1.8 1 PLAT PLAT/LH2 domain 1.4e-15 58.5 0.1 2.8e-15 57.4 0.1 1.6 1 Lectin_C Lectin C-type domain 2e-12 48.5 0.1 6.7e-12 46.8 0.1 2.0 1 CAP Cysteine-rich secretory protein family 6.6e-08 33.2 7.2 6.6e-08 33.2 7.2 3.0 3 EGF EGF-like domain 0.004 18.0 2.6 0.004 18.0 2.6 3.3 4 hEGF Human growth factor-like EGF 0.0088 16.5 2.4 0.0088 16.5 2.4 2.7 3 JAG1-like_EGF2 Protein jagged-1-like, atypical EGF2 Domain annotation for each model (and alignments): >> PLAT PLAT/LH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.6 0.1 1.6e-19 6.6e-16 1 104 [. 48 148 .. 48 153 .. 0.93 Alignments for each domain: == domain 1 score: 59.6 bits; conditional E-value: 1.6e-19 PLAT 1 yqvkvvtgdkkgagtdadvyislygkvgksaqleltldtsgpdfergaedsfevdtdwdlGallkinlhwdnkgisdewflksitvekpgetgkkv 96 y ++v+ ++++ a+ d + + +yg++g++ +l+l + +df++g++d+f+v++ dlG++ ki l ++n +++++w+l++it+ ++++g + FUN_000883-T1 48 YIIQVKAANQRAAARDSNLFLDIYGSKGTASKLKLGNLMTFNDFQSGKTDQFKVKLR-DLGEIRKITLGHHNFARKPNWYLDRITI--KAHDGNNY 140 889***************************99988888566**************99.7***********99999999********..5899**** PP PLAT 97 tFpcnsWv 104 +F cn ++ FUN_000883-T1 141 KFICNCTI 148 *****776 PP >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.4 0.1 6.6e-19 2.8e-15 2 106 .. 1320 1426 .. 1319 1427 .. 0.92 Alignments for each domain: == domain 1 score: 57.4 bits; conditional E-value: 6.6e-19 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllk.ksnkkfWigltdeksegtwkwedgskvnteeytnw..epnnngenedCvel..ekssg 90 +++w+++ C+ +g+L+s++skee +++ sl++ ++++++Wigl+d+ seg + w dgs +++w + n + +e+C + + FUN_000883-T1 1320 PLTWDDSIYGCALDNGSLASLQSKEEADLVVSLIRaSNESEAWIGLHDSSSEGRYVWLDGSAIP---FSEWlqGEPNGRTSENCIIQskGTFLS 1410 679*******************************9899999***********************...899998555888999999887666678 PP Lectin_C 91 kwndesCnsknpfvCe 106 w d++C++k++fvCe FUN_000883-T1 1411 GWADRPCSEKKAFVCE 1426 9**************8 PP >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.8 0.1 1.6e-15 6.7e-12 3 115 .. 1147 1266 .. 1145 1270 .. 0.89 Alignments for each domain: == domain 1 score: 46.8 bits; conditional E-value: 1.6e-15 CAP 3 lhNelRaaaglppLswdaeLaaaAqehaktcaeng..shnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa....... 87 ++ ++R+ +++p ++ + +L+++A+++a+++a+ g + +++s++g+ + + ++ +a++ v +Wy ++++++ FUN_000883-T1 1147 EIDNFRRLHQAPDVKLSVTLSQVANQWANKIANEGveRIDPNSNYGQLVCSHNVGGN---------TAKACVVKWYGAIRFFDWSNPkltknas 1231 6899***************************99999899999999988888888777.........********************9******* PP CAP 88 hrtnllwpkstkvGcavakcgdgsy.......vfv 115 +t+l+w++++ +G++va++g+g + +f+ FUN_000883-T1 1232 PFTQLVWKNNSAIGVGVARGGGGIKkqnvggkNFI 1266 *********************99887666666444 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.2 7.2 1.5e-11 6.6e-08 1 31 [. 417 449 .. 417 450 .. 0.97 2 ? -3.1 0.1 3.4 1.4e+04 5 10 .. 1498 1505 .. 1496 1506 .. 0.67 3 ? -13.6 11.1 6 2.6e+04 11 22 .. 1569 1579 .. 1561 1580 .. 0.57 Alignments for each domain: == domain 1 score: 33.2 bits; conditional E-value: 1.5e-11 EGF 1 CspnpCsngGtC...vdtprggytCiCpeGytGk 31 C+p+pC ngGtC vd p gy C CpeG++G FUN_000883-T1 417 CNPTPCFNGGTCkidVDEP-RGYRCVCPEGFAGL 449 *******************.************96 PP == domain 2 score: -3.1 bits; conditional E-value: 3.4 EGF 5 p..CsngG 10 + C+n+G FUN_000883-T1 1498 TirCMNNG 1505 45588887 PP == domain 3 score: -13.6 bits; conditional E-value: 6 EGF 11 tCvdtprggytC 22 C ++ + ++C FUN_000883-T1 1569 SCQPGC-DQFCC 1579 366666.77777 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.5 6 2.6e+04 13 18 .. 141 146 .. 136 147 .. 0.72 2 ? -2.9 0.1 3.7 1.6e+04 5 16 .. 234 243 .. 233 244 .. 0.68 3 ! 18.0 2.6 9.4e-07 0.004 1 22 [] 422 446 .. 422 446 .. 0.80 4 ? -3.3 0.1 4.9 2.1e+04 1 6 [. 1501 1506 .. 1501 1508 .. 0.82 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 6 hEGF 13 gykCqC 18 + C C FUN_000883-T1 141 KFICNC 146 489999 PP == domain 2 score: -2.9 bits; conditional E-value: 3.7 hEGF 5 GtCvdgvngykC 16 G+C+ + ++C FUN_000883-T1 234 GKCI--SEPNLC 243 7999..555666 PP == domain 3 score: 18.0 bits; conditional E-value: 9.4e-07 hEGF 1 ClNGGtCv.dgvng..ykCqCppGy 22 C NGGtC d y+C+Cp+G+ FUN_000883-T1 422 CFNGGTCKiDVDEPrgYRCVCPEGF 446 *******744433366********9 PP == domain 4 score: -3.3 bits; conditional E-value: 4.9 hEGF 1 ClNGGt 6 C+N+G+ FUN_000883-T1 1501 CMNNGS 1506 999996 PP >> JAG1-like_EGF2 Protein jagged-1-like, atypical EGF2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.7 2.5 1.1e+04 16 23 .. 169 176 .. 167 177 .. 0.83 2 ! 16.5 2.4 2.1e-06 0.0088 3 23 .. 426 452 .. 424 453 .. 0.89 3 ? -3.1 0.3 2.9 1.3e+04 8 11 .. 1640 1643 .. 1639 1645 .. 0.90 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 2.5 JAG1-like_EGF2 16 GwgGlFCD 23 G gG+F D FUN_000883-T1 169 GCGGIFTD 176 88****88 PP == domain 2 score: 16.5 bits; conditional E-value: 2.1e-06 JAG1-like_EGF2 3 GtCkep......wqCtCdEGwgGlFCD 23 GtCk+ C C+EG++Gl C FUN_000883-T1 426 GTCKIDvdeprgYRCVCPEGFAGLQCE 452 99*9877777999***********996 PP == domain 3 score: -3.1 bits; conditional E-value: 2.9 JAG1-like_EGF2 8 pwqC 11 pwqC FUN_000883-T1 1640 PWQC 1643 9*** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1674 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1136 (0.0444705); expected 510.9 (0.02) Passed bias filter: 476 (0.0186338); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.70u 0.40s 00:00:01.10 Elapsed: 00:00:00.42 # Mc/sec: 15911.08 // Query: FUN_000884-T1 [L=108] Description: FUN_000884 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0014 19.0 0.4 0.0017 18.7 0.4 1.3 1 LemA LemA family 0.0032 18.3 0.6 0.0042 17.9 0.6 1.3 1 DUF3135 Protein of unknown function (DUF3135) ------ inclusion threshold ------ 0.01 16.3 1.1 0.014 15.9 1.1 1.2 1 DUF1515 Protein of unknown function (DUF1515) 0.02 15.7 3.6 0.023 15.4 3.6 1.1 1 Troponin Troponin 0.032 13.8 1.7 0.037 13.6 1.7 1.1 1 ATG14 Vacuolar sorting 38 and autophagy-related subunit 1 0.12 13.3 7.3 3 8.8 0.9 2.9 3 ERM_C Ezrin/radixin/moesin family C terminal Domain annotation for each model (and alignments): >> LemA LemA family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.4 3.9e-07 0.0017 79 139 .. 39 99 .. 13 108 .] 0.85 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 3.9e-07 LemA 79 anenfleLqeeLegtEnriavaRrrYneavreyntkiesfpsnlvaklfgfkekeyfeaee 139 +n++ + Lqe+L++++ ri vaR ++ ++v+ + ++e++ +nl+ +k ++ ++++ FUN_000884-T1 39 SNNRTQVLQERLRTLQSRIDVARLDFKKQVEGLRMRMEHLNTNLTTIQGDMKMRDPVKTRN 99 789999**************************************98888888777777644 PP >> DUF3135 Protein of unknown function (DUF3135) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.6 9.9e-07 0.0042 17 76 .. 25 84 .. 17 89 .. 0.80 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 9.9e-07 DUF3135 17 eaLealrqelieelIesapeelqrrLrglqfqidmqleraknPvhacvalsammheklee 76 e+ e+l++ +e+ +++++ lq+rLr lq++id + k v+ ++ ++ l + FUN_000884-T1 25 ETQENLKKLSPKEISNNRTQVLQERLRTLQSRIDVARLDFKKQVEGLRMRMEHLNTNLTT 84 6668888888899999999****************9988888887777777777666665 PP >> DUF1515 Protein of unknown function (DUF1515) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 1.1 3.2e-06 0.014 18 70 .. 44 96 .. 36 104 .. 0.90 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 3.2e-06 DUF1515 18 knlredlrrsedksdvirvsmtrrmdelvervrtlegstvlvkddiaemkpvt 70 + l+e lr + + dv+r ++++++ l r++ l+ + +++d+ pv FUN_000884-T1 44 QVLQERLRTLQSRIDVARLDFKKQVEGLRMRMEHLNTNLTTIQGDMKMRDPVK 96 5689******************************************9999984 PP >> Troponin Troponin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 3.6 5.5e-06 0.023 17 96 .. 12 90 .. 2 106 .. 0.83 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 5.5e-06 Troponin 17 ekeqekkeeekeraLaerieplralrglseeelqelckelheridkleeerydleekvakkdkeieelkikvldlrGkfk 96 e+++ ek +e++++l+ +++s++ q l ++l+ + +++ r d ++v+ + +e l+ +++G +k FUN_000884-T1 12 PSETKRTYLEKDSETQENLKKLS-PKEISNNRTQVLQERLRTLQSRIDVARLDFKKQVEGLRMRMEHLNTNLTTIQGDMK 90 56777777788888888888988.7888999999999999999**********************************976 PP >> ATG14 Vacuolar sorting 38 and autophagy-related subunit 14 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 1.7 8.7e-06 0.037 66 118 .. 31 83 .. 4 91 .. 0.80 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8.7e-06 ATG14 66 elksevaeseerlkeikdkldqlkkeieekkkkiaklrsslkkrrsdlesasn 118 ++ s ++ s++r++ ++++l +l+++i++++ ++k+ + l r++ l+ + + FUN_000884-T1 31 KKLSPKEISNNRTQVLQERLRTLQSRIDVARLDFKKQVEGLRMRMEHLNTNLT 83 44567899*********************************999998876655 PP >> ERM_C Ezrin/radixin/moesin family C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.9 0.0007 3 5 34 .. 13 43 .. 10 45 .. 0.84 2 ? 8.0 0.4 0.0013 5.5 13 38 .. 41 66 .. 36 70 .. 0.86 3 ? 1.1 0.1 0.18 7.6e+02 14 30 .. 74 90 .. 63 106 .. 0.60 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0007 ERM_C 5 eeervteaeknkrlqeqLkeLk.selaeard 34 e + t++ek+ + qe+Lk+L+ +e+++ r FUN_000884-T1 13 SETKRTYLEKDSETQENLKKLSpKEISNNRT 43 57799****************8568877775 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0013 ERM_C 13 eknkrlqeqLkeLkselaeardeekk 38 ++ + lqe+L++L+s +++ar + kk FUN_000884-T1 41 NRTQVLQERLRTLQSRIDVARLDFKK 66 67899****************98665 PP == domain 3 score: 1.1 bits; conditional E-value: 0.18 ERM_C 14 knkrlqeqLkeLksela 30 + ++l+ +L +++ +++ FUN_000884-T1 74 RMEHLNTNLTTIQGDMK 90 44555555555555543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (108 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1501 (0.0587591); expected 510.9 (0.02) Passed bias filter: 601 (0.0235271); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1110.78 // Query: FUN_000885-T1 [L=179] Description: FUN_000885 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-12 49.4 0.2 1.4e-12 49.0 0.2 1.1 1 CAP Cysteine-rich secretory protein family 0.0076 16.1 0.0 0.01 15.7 0.0 1.1 1 Imm11 Immunity protein family (Imm11) Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.0 0.2 1.1e-16 1.4e-12 2 119 .] 43 159 .. 42 160 .. 0.90 Alignments for each domain: == domain 1 score: 49.0 bits; conditional E-value: 1.1e-16 CAP 2 dlhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hrt 90 ++N +R ++ +pL +d+ L +aA++ a t + +s+++ +i++++a++ ++++ +++ + v +Wy +++++ ++ + FUN_000885-T1 43 TYINVFRHMHASAPLLVDDVLQKAAENAASTY-----MKANSKDKVPIYQYSANFC-KYTGPESTLDRTCVISWYVTMKYFSWCYPkaegqalPFV 132 689***************************96.....7789999999999999999.6777777777889*********9*99999********** PP CAP 91 nllwpkstkvGcavakcgdgsyvfvvcny 119 n++w++stkvG+++ak +dg+y +v++y FUN_000885-T1 133 NMIWKASTKVGVGIAKASDGTY--FVVVY 159 ********************99..66555 PP >> Imm11 Immunity protein family (Imm11) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 8e-07 0.01 141 185 .. 29 73 .. 12 80 .. 0.89 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 8e-07 Imm11 141 lvggaslvfkedlvggaHvFrlkeagssvivddilkealeaaklt 185 +v + ++++d+v vFr+ +a+ ++vdd+l +a e+a +t FUN_000885-T1 29 VVSSVKATIQRDVVTYINVFRHMHASAPLLVDDVLQKAAENAAST 73 56678999******************************9998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 670 (0.0262282); expected 510.9 (0.02) Passed bias filter: 497 (0.0194559); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1813.99 // Query: FUN_000886-T1 [L=74] Description: FUN_000886 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.1e-07 30.2 0.0 1e-06 29.9 0.0 1.2 1 Lectin_C Lectin C-type domain 0.00043 20.4 0.0 0.00043 20.4 0.0 1.0 1 UL45 UL45 protein, carbohydrate-binding C-type lectin-li Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.0 8.1e-11 1e-06 2 46 .. 27 73 .. 26 74 .] 0.94 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 8.1e-11 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllk..ksnkkfWigl 46 + +w+ea C++e+++L+si+++ e+ f++ l + s+ ++Wig+ FUN_000886-T1 27 AVTWDEALVRCASENATLASIRNSDEETFVRDLQRktGSSVETWIGM 73 579*****************************9888899999****8 PP >> UL45 UL45 protein, carbohydrate-binding C-type lectin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.0 3.4e-08 0.00043 72 116 .. 5 48 .. 1 72 [. 0.78 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 3.4e-08 UL45 72 esapCpaewiglgdsCirpigknakteeeavatCaayssklisrs 116 a Cp + ++ sC + +++ + t ea+ Ca +++l+s FUN_000886-T1 5 DKADCPTGFYRFKTSCFKYVPTAV-TWDEALVRCASENATLASIR 48 6789********************.***************98743 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (74 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 577 (0.0225876); expected 510.9 (0.02) Passed bias filter: 513 (0.0200822); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 763.32 // Query: FUN_000887-T1 [L=903] Description: FUN_000887 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-05 23.5 0.1 6.6e-05 23.5 0.1 3.5 4 SEA SEA domain 0.0028 18.1 0.0 0.012 16.0 0.0 2.0 2 DUF1441 Protein of unknown function (DUF1441) ------ inclusion threshold ------ 0.033 15.4 0.1 0.033 15.4 0.1 3.4 4 Lectin_C Lectin C-type domain 0.071 13.6 0.6 29 5.3 0.3 3.1 2 DUF5673 Domain of unknown function (DUF5673) 4.7 7.5 6.6 3.8 7.7 2.5 2.3 2 Colipase Colipase, N-terminal domain Domain annotation for each model (and alignments): >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.1 1.3e-08 6.6e-05 9 85 .. 84 160 .. 77 170 .. 0.87 2 ? -0.6 3.5 0.4 2e+03 3 90 .. 403 488 .. 401 498 .. 0.74 3 ? -3.6 0.1 3.3 1.7e+04 24 41 .. 535 552 .. 526 564 .. 0.56 4 ? -1.6 0.4 0.81 4.1e+03 5 39 .. 730 764 .. 729 770 .. 0.78 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 1.3e-08 SEA 9 itnleytedlenpsSeefkslskkiesllnelfrkss..lkkqyiksevlrlspekgsvvvdvvlvfrfpstenaldre 85 +++ ++++++++++S+++++l + i ++e+f + s k +++++v ++p +++++ + + fr+ +++++l + FUN_000887-T1 84 FKKFRWNPSYKDKNSKAYRDLLNGIRVTFKEIFTRKSgkTKGGFRNATVKGVRP--NGLGISIKVQFRSFNADPTLRFQ 160 566789***************************9977568899***********..************98777776655 PP == domain 2 score: -0.6 bits; conditional E-value: 0.4 SEA 3 ytgsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspe.kgsvvvdvvlvfrfpstenaldrekliee 90 +t+++ t+ ++ +++psS + + k+++s+++ +ss ++ +++++ +l+ +++ ++++++++++++++ ++ ++i++ FUN_000887-T1 403 FTINLNKTQNFHQPAFSEPSSLQQN---KDVKSAVEAMTDHSSKEQMTKENHLNKLNTTtGENKNNHFTVILNKTAQDSRPSMFDKINN 488 4444444555566666666666554...5677777777778888999999999999877789999999999999988888888777765 PP == domain 3 score: -3.6 bits; conditional E-value: 3.3 SEA 24 eefkslskkiesllnelf 41 ++f++ +++i++ ++ + FUN_000887-T1 535 QNFNERTEDINRRFSTTK 552 455555555555444433 PP == domain 4 score: -1.6 bits; conditional E-value: 0.81 SEA 5 gsfkitnleytedlenpsSeefkslskk.iesllne 39 +sf+++n e + + +n+s ++ +l+k+ +e+l++ FUN_000887-T1 730 SSFHLLN-EHSNNIRNESDQKPEDLEKQsVENLIDT 764 6899999.8999999999999999987625666665 PP >> DUF1441 Protein of unknown function (DUF1441) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 1.4 7.1e+03 28 65 .. 504 541 .. 502 548 .. 0.77 2 ! 16.0 0.0 2.3e-06 0.012 16 76 .. 614 675 .. 605 689 .. 0.91 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 1.4 DUF1441 28 sagsvkknklyllvdvlaalieapliaaeeeqdPnkmt 65 s + ++++ + l+ ++++++p+i+ ++ q+ n+ t FUN_000887-T1 504 SERKRSNQTFFNLLRGGSSAMTTPVIQHKHLQNFNERT 541 55566777777788888899*******99999988655 PP == domain 2 score: 16.0 bits; conditional E-value: 2.3e-06 DUF1441 16 qtvasrLkgvevsagsvkknklyllvdvlaalieapliaaeeeqdPnkmtP.kerkaWfdse 76 t++++++g ++s+ +++n++y + ++ ++ ++ a+ + ++ P +erk+ fd FUN_000887-T1 614 TTIKNKIQGSKLSPLDGEENNIYTHENIHPDYLINDIPEAKRSNASSQLSPlQERKQMFDEW 675 69*************************************************779*****965 PP >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.1 6.4e-06 0.033 45 106 .. 7 69 .. 2 70 .. 0.85 2 ? -2.1 0.3 1.8 9.4e+03 48 72 .. 347 375 .. 330 414 .. 0.56 3 ? -2.3 0.9 2.1 1.1e+04 37 68 .. 398 430 .. 371 479 .. 0.51 4 ? -1.8 0.8 1.5 7.5e+03 38 72 .. 680 719 .. 656 753 .. 0.52 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 6.4e-06 Lectin_C 45 gltdeksegtwkwedgskvntee...ytnwepnnngenedCvel..ekssgkwndesCnsknpfvCe 106 gl+d+ +eg +k dg + ++ + n g +e+Cv++ ek g w+d+sC +k p+ C+ FUN_000887-T1 7 GLNDNLREGRFKFFDGLRFKPGVcvpV----NANGGMQENCVAWsiEKPEGCWEDRSCGEKIPYTCR 69 888888999999999999998764322....689999*****************************7 PP == domain 2 score: -2.1 bits; conditional E-value: 1.8 Lectin_C 48 deksegtwkwedgskvntee...ytnw.e 72 ++ ++g+ +w+ +++++t y++ FUN_000887-T1 347 YHGNDGSRRWTFDQENKTGYdqkYKKSlG 375 45555555555444444432223333332 PP == domain 3 score: -2.3 bits; conditional E-value: 2.1 Lectin_C 37 ksnkkfWigltdeksegtwkwedgskvntee.y 68 ++ ++f i l+++++ ++ ++ s +++++ FUN_000887-T1 398 NPREHFTINLNKTQNFHQPAFSEPSSLQQNKdV 430 455555555555555554444444444433331 PP == domain 4 score: -1.8 bits; conditional E-value: 1.5 Lectin_C 38 snkkfWigltdeksegtwkwedgskvntee....ytnw..e 72 sn++ ++l ++ ++ +++ d++++++++ +++w + FUN_000887-T1 680 SNEHLSTSL-NNSEDSRMTVFDKEDNKYDNgrgdTNEWigD 719 444445555.4444444444444444444444443444331 PP >> DUF5673 Domain of unknown function (DUF5673) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.0075 38 29 54 .. 340 363 .. 332 367 .. 0.84 2 ? 5.3 0.3 0.0057 29 24 54 .. 674 704 .. 671 706 .. 0.92 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0075 DUF5673 29 eeknklvliyktnkkkrrlkfkkedi 54 +e + ++y+ n ++rr++f+ e++ FUN_000887-T1 340 NE--HVDVNYHGNDGSRRWTFDQENK 363 44..77789***************98 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0057 DUF5673 24 sYsldeeknklvliyktnkkkrrlkfkkedi 54 +s ++ +++l+ ++ +++++r ++f+ked FUN_000887-T1 674 EWSTETSNEHLSTSLNNSEDSRMTVFDKEDN 704 6999999**********************97 PP >> Colipase Colipase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.1 0.1 5.2e+02 10 25 .. 187 202 .. 186 206 .. 0.84 2 ? 7.7 2.5 0.00075 3.8 18 28 .. 267 277 .. 260 279 .. 0.90 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.1 Colipase 10 dGElClNSaQCKSkCC 25 +G+ C NS K C FUN_000887-T1 187 AGDYCYNSCHHKHTCA 202 6999****99999995 PP == domain 2 score: 7.7 bits; conditional E-value: 0.00075 Colipase 18 aQCKSkCCqhe 28 +QCK +CC h FUN_000887-T1 267 MQCKDECCDHR 277 8*******996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (903 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1957 (0.0766099); expected 510.9 (0.02) Passed bias filter: 427 (0.0167156); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.40u 0.42s 00:00:00.82 Elapsed: 00:00:00.40 # Mc/sec: 9018.78 // Query: FUN_000888-T1 [L=2044] Description: FUN_000888 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-34 119.7 0.0 3.2e-34 119.1 0.0 1.3 1 VWA von Willebrand factor type A domain 4.1e-14 53.7 0.6 1.1e-13 52.3 0.3 1.9 2 Lectin_C Lectin C-type domain 2e-12 48.5 0.1 5.9e-12 47.0 0.0 1.9 2 CAP Cysteine-rich secretory protein family 1.5e-10 42.1 0.0 3.1e-10 41.1 0.0 1.6 1 VWA_2 von Willebrand factor type A domain 2.2e-08 34.9 0.1 6.5e-08 33.3 0.1 1.9 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfami 5.4e-07 30.2 4.3 2e-06 28.4 4.3 2.1 1 EGF EGF-like domain 4.9e-05 23.9 0.2 0.00014 22.5 0.2 1.7 1 SEA SEA domain 0.0055 17.6 4.4 0.0055 17.6 4.4 2.9 2 hEGF Human growth factor-like EGF ------ inclusion threshold ------ 4.5 7.9 10.6 0.1 13.2 3.3 2.1 3 EGF_Teneurin Teneurin-like EGF domain Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 119.1 0.0 1.1e-37 3.2e-34 1 172 [. 13 186 .. 13 188 .. 0.96 Alignments for each domain: == domain 1 score: 119.1 bits; conditional E-value: 1.1e-37 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrtefslndysskeellsavkslkykgggttntgkalkyalenlfkss 96 D+vf +D+Sgs+g+ + + + f+ ++v+++ i++ +t+v+++ ys++++ e++l+++ s + ++ a+ +l+yk g+t+ ++ alk a+e +f ++ FUN_000888-T1 13 DLVFAIDASGSVGQWGYFQEQMFVRRVVQRFGISQSGTHVAVIEYSTRAKAEIPLTRFYSYSRFYYALGKLPYKRGETR-IDLALKVAAEDVFGPE 107 9******************************************************************************.**************** PP VWA 97 agaRegapkvvvlltdGksqdg....dveeaarelksagvkvfavgvgnadeee.Lekiasepdeghvftvedfealeelq 172 g+R+++pk++vl+tdG ++ +++a+ l+s+gvkvfa+++gn ++e L+ i +++d h+f++++f+ l ++ FUN_000888-T1 108 GGSRSNVPKILVLMTDGSQTHRrgviPLDKAVLPLRSKGVKVFALAIGNYPNKEeLRLIVEKKD--HIFKSNSFSVLLSII 186 *******************77447*9999********************999999*********..********9876665 PP >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 5.5 1.6e+04 42 64 .. 437 460 .. 431 466 .. 0.72 2 ! 52.3 0.3 3.9e-17 1.1e-13 2 104 .. 811 913 .. 810 915 .. 0.95 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 5.5 Lectin_C 42 fWigltdeksegt.wkwedgskvn 64 ++iglt+ ++ t w++g+ v FUN_000888-T1 437 YFIGLTYDNNLRTaALWVNGRAVA 460 89***8777765515688777665 PP == domain 2 score: 52.3 bits; conditional E-value: 3.9e-17 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllk.ksnkkfWigltdeksegtwkwedgskvnteeytnw.epnnngenedCvel.ekssgkwnd 94 k++we a + e+++Lvs++++++++f++ l++ +++ +W+gl+d+ +egt++w+dg+ v+ y+ w e++++g++edCv + s g+++d FUN_000888-T1 811 KQTWEAALFQSAMENATLVSFHKSQQEAFVQRLIPsGYQEIIWTGLNDRITEGTYTWSDGTSVE---YSTWkENEPTGRKEDCVGVqVISYGTMSD 903 6799999999999**********************9999*************************...999999999********99889******* PP Lectin_C 95 esCnsknpfv 104 ++C++ +++v FUN_000888-T1 904 VPCTQLHNYV 913 ******9998 PP >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.0 0.0 2.1e-15 5.9e-12 1 119 [] 645 763 .. 645 763 .. 0.94 2 ? -2.7 0.0 5.3 1.5e+04 17 59 .. 813 850 .. 811 872 .. 0.69 Alignments for each domain: == domain 1 score: 47.0 bits; conditional E-value: 2.1e-15 CAP 1 ldlhNelRaaaglppLswdaeLaaaAqehaktcaeng..shnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa....... 87 ++++N++R+ +g+ p+ + + +++Aq +a+t+ ++g s ++++++g+n+++rv++ + a+ a+ +Wy++ +++++++ FUN_000888-T1 645 VEYINRFRRIHGAGPVILSMRISTVAQSWAQTLVTRGtaSIDPNTSYGTNVFTRVGSQT--------GLAQIAAVTWYSSVKYFDWAQRklkilal 732 589*********************************9**********************........666666668******************** PP CAP 88 hrtnllwpkstkvGcavakcgdgsyvfvvcny 119 + ++w +s+ vG++ ak+++ ++ +vv+++ FUN_000888-T1 733 PFVHMIWLSSNFVGVGLAKSSSSKF-YVVVYF 763 *********************9988.677665 PP == domain 2 score: -2.7 bits; conditional E-value: 5.3 CAP 17 swdaeLaaaAqehaktcaengshnhrsptggnilarvaaagr.e 59 +w a+L + A+e+a + ++++ + +++r ++g+ e FUN_000888-T1 813 TWEAALFQSAMENATLV------SFHKSQQEAFVQRLIPSGYqE 850 68899999999999866......667777777777777777652 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.1 0.0 1.1e-13 3.1e-10 1 107 [. 14 124 .. 14 126 .. 0.89 Alignments for each domain: == domain 1 score: 41.1 bits; conditional E-value: 1.1e-13 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallksl....pgdrvglvtfsdnpevliplt..kdkakllealrrleatgggtdlaaAlqlarkalk 90 lvf +D SgS+++ + + + +v+++++++ g v+++ +s++++ +iplt +++++ al +l ++g+t++ Al++a++ ++ FUN_000888-T1 14 LVFAIDASGSVGQWG-----YFQEQMFVRRVVQRFgisqSGTHVAVIEYSTRAKAEIPLTrfYSYSRFYYALGKLPYKRGETRIDLALKVAAEDVF 104 69*********9884.....5566779999999555553799*****************98999****************************9888 PP VWA_2 91 krr...rknakriivlitDg 107 + r+n ++i+vl+tDg FUN_000888-T1 105 GPEggsRSNVPKILVLMTDG 124 777889*************9 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.1 2.3e-11 6.5e-08 16 150 .. 373 506 .. 354 507 .. 0.80 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 2.3e-11 Laminin_G_3 16 tsafTvsaWvkpdsapqssralvsessgggyelgldsdg..qlrftvnggngaeeavtsgasvpagqWtHvavtydg..gtlrlYvnGeevgsstl 107 sa ++ +Wv+ + p+ + g g+ l++++ ++++ + ++ +++ + +W+++ tyd+ t+ l vnG v++ + FUN_000888-T1 373 WSAVSIFLWVYSEGKPGPIVNYG--RVGHGLGLWMRGRRllGGYIYSRHNF--YRRRMYYYNLIPRRWYFIGLTYDNnlRTAALWVNGRAVAQMRM 464 67889999999999999665555..66779999998888444445544444..445556789999***********63478***********9985 PP Laminin_G_3 108 tgaltkatggplyiGrdnggdspfdGlidevriynraLsaeei 150 +++ atg p+++G+ g +++f+G++ ++iy aL+a++i FUN_000888-T1 465 -SRIYLATGYPVRMGAVTGVGQYFKGRVTCLQIYGMALTADDI 506 .5567789**********999********************98 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.4 4.3 7.2e-10 2e-06 1 32 [] 522 555 .. 522 555 .. 0.94 Alignments for each domain: == domain 1 score: 28.4 bits; conditional E-value: 7.2e-10 EGF 1 CspnpCsngGtCvdtp..rggytCiCpeGytGkr 32 C + pC+ngG C+ + gy C+C++Gy G r FUN_000888-T1 522 CLSSPCLNGGSCIFDSaqQKGYLCRCKPGYRGLR 555 9999********88888**************976 PP >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.2 4.8e-08 0.00014 3 61 .. 924 979 .. 922 991 .. 0.89 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 4.8e-08 SEA 3 ytgsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspe 61 y+ +++++ l++ted+++psS + +l++kie+ll ++++ ++ +++ v +++++ FUN_000888-T1 924 YRTKLQLLLLPWTEDYRQPSSLTYLELKQKIETLLLAIYNN---YETFVSGYVENFRKN 979 7778888899*******************************...999999999999997 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 4.4 1.9e-06 0.0055 1 22 [] 527 551 .. 527 551 .. 0.95 2 ? -1.2 0.2 1.6 4.7e+03 18 22 .] 793 797 .. 792 797 .. 0.90 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 1.9e-06 hEGF 1 ClNGGtCv.dgvng..ykCqCppGy 22 ClNGG+C+ d + y+C+C+pGy FUN_000888-T1 527 CLNGGSCIfDSAQQkgYLCRCKPGY 551 ********99998889********9 PP == domain 2 score: -1.2 bits; conditional E-value: 1.6 hEGF 18 CppGy 22 C+pGy FUN_000888-T1 793 CNPGY 797 ****9 PP >> EGF_Teneurin Teneurin-like EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.0 0.0 8.6 2.4e+04 9 18 .. 484 493 .. 482 494 .. 0.79 2 ? 13.2 3.3 3.7e-05 0.1 6 29 .. 528 558 .. 524 559 .. 0.85 3 ? -2.9 0.1 3.9 1.1e+04 17 22 .. 792 797 .. 792 798 .. 0.86 Alignments for each domain: == domain 1 score: -4.0 bits; conditional E-value: 8.6 EGF_Teneurin 9 GtCkkGsCaC 18 G++ kG+ +C FUN_000888-T1 484 GQYFKGRVTC 493 9*****9666 PP == domain 2 score: 13.2 bits; conditional E-value: 3.7e-05 EGF_Teneurin 6 gghGtCkkGs.......CaCesGWkGeeCdv 29 G C+ +s C+C++G++G C++ FUN_000888-T1 528 LNGGSCIFDSaqqkgylCRCKPGYRGLRCEI 558 55689988888899999************97 PP == domain 3 score: -2.9 bits; conditional E-value: 3.9 EGF_Teneurin 17 aCesGW 22 +C++G+ FUN_000888-T1 792 TCNPGY 797 6****9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2044 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1017 (0.0398121); expected 510.9 (0.02) Passed bias filter: 563 (0.0220395); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.59u 0.41s 00:00:01.00 Elapsed: 00:00:00.44 # Mc/sec: 18727.52 // Query: FUN_000889-T1 [L=969] Description: FUN_000889 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-09 39.4 0.4 1.1e-09 39.4 0.4 2.7 4 Lectin_C Lectin C-type domain 7.6e-05 24.0 0.0 0.00019 22.8 0.0 1.7 1 CAP Cysteine-rich secretory protein family 0.00039 21.0 0.0 0.00089 19.8 0.0 1.6 1 SEA SEA domain ------ inclusion threshold ------ 0.022 14.6 0.1 0.042 13.6 0.1 1.4 1 Chordopox_A33R Chordopoxvirus A33R protein Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.3 0.55 3.5e+03 46 99 .. 50 107 .. 46 111 .. 0.70 2 ? -2.6 0.0 2 1.3e+04 65 90 .. 140 163 .. 127 166 .. 0.63 3 ? -3.6 0.0 4 2.6e+04 28 51 .. 191 212 .. 183 217 .. 0.64 4 ! 39.4 0.4 1.8e-13 1.1e-09 2 107 .] 268 374 .. 267 374 .. 0.92 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.55 Lectin_C 46 ltdeksegtwkwedgskvntee......ytnw.epnnngenedCvelekssgkwndesCns 99 l++++s+++w ++d+++ e+ n ++ ++++ + l ++ +++d+ C++ FUN_000889-T1 50 LSSKNSNNDWLTDDDDDDDEENldeglrL-NAqAVTKPTKKPTAAPL--TNTQLEDKICEY 107 67889999999999999997777776541.22344556666666666..888888888876 PP == domain 2 score: -2.6 bits; conditional E-value: 2 Lectin_C 65 teeytnw.epnnngenedCvelekssg 90 t ++ + +pn ++++ +C +l ++s+ FUN_000889-T1 140 TGQI--KsNPNIKHGQLQCIKL-TTSD 163 2222..2579999999999999.4443 PP == domain 3 score: -3.6 bits; conditional E-value: 4 Lectin_C 28 nkflssllkksnkkfWigltdeks 51 nkf+ + ++++++ig +k+ FUN_000889-T1 191 NKFFVTAT--YKNSTYIGAAASKT 212 44444444..78888888755555 PP == domain 4 score: 39.4 bits; conditional E-value: 1.8e-13 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllk.ksnkkfWigltdeksegtwkwedgskvnteeytnw.epnnngenedCvel..ekssgkwn 93 +++w +a+ C ke ++L+ i++++e++++++ l ++ ++W+ +d+ se+ + +dgs+ + y +w + ++g+ ++Cv+ e++ g++ FUN_000889-T1 268 PQTWMNANIECIKELAFLPPIKNAQEKDYFKQGLLrGQKGSTWLAFNDRLSESMYMSVDGSQIE---YMDWaSDYPKGKGSNCVAFnnEAKYGTMA 360 579********************88777776655449999************************...999*98899***********999****** PP Lectin_C 94 desCnsknpfvCek 107 d++C++ +++vC+k FUN_000889-T1 361 DYPCTKTYTYVCKK 374 ************96 PP >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.0 2.9e-08 0.00019 2 116 .. 106 220 .. 105 223 .. 0.88 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 2.9e-08 CAP 2 dlhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hrt 90 +++N++R++ g+ pL ++L + A+ +++ +++++ +++ ni + + + +++ + + ++ W+ + ++y+++++ + FUN_000889-T1 106 EYINAIRTRMGAGPLIRLKTLDVGAKISNAQM----QRTGQIKSNPNIKHGQLQCI--KLTTSDKVPIECLAFWIAQMQDYDWSKPaikdnnkFFV 195 689*****************************....66777777777777777777..777789**************************998888 PP CAP 91 nllwpkstkvGcavakcgdgsyvfvv 116 +++st++G a++k ++g+y fv+ FUN_000889-T1 196 TATYKNSTYIGAAASKTSSGRY-FVT 220 8999*****************9.443 PP >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 1.4e-07 0.00089 3 44 .. 382 423 .. 380 432 .. 0.92 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 1.4e-07 SEA 3 ytgsfkitnleytedlenpsSeefkslskkiesllnelfrks 44 + + +++ ++ + +d++n++S ++++l+ k+++ ++e+++k FUN_000889-T1 382 FLFELTVESMVWLDDFSNQGSLAYQQLAAKFQKSIQEVYKKA 423 678899*********************************995 PP >> Chordopox_A33R Chordopoxvirus A33R protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 6.5e-06 0.042 108 138 .. 257 287 .. 232 309 .. 0.81 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 6.5e-06 Chordopox_A33R 108 fdsacyrlvkepktfseaskdcakkkaslPa 138 + ++cy+++k+p+t+ +a +c+k+ a lP FUN_000889-T1 257 YSGSCYKFHKDPQTWMNANIECIKELAFLPP 287 8899***********************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (969 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 872 (0.0341358); expected 510.9 (0.02) Passed bias filter: 505 (0.019769); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.47u 0.36s 00:00:00.83 Elapsed: 00:00:00.41 # Mc/sec: 9440.22 // Query: FUN_000891-T1 [L=764] Description: FUN_000891 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-49 168.9 18.8 2.9e-49 168.4 18.8 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 6.5e-21 75.5 0.0 1e-20 74.9 0.0 1.3 1 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 1.7e-12 47.8 18.0 2.6e-12 47.2 18.0 1.3 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.031 14.4 0.0 0.15 12.2 0.0 2.0 1 Pentaxin Pentaxin family 0.24 11.6 0.0 0.41 10.9 0.0 1.4 1 Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor b 1.4 8.5 15.9 3.7 7.1 15.9 1.7 1 TAS2R Taste receptor protein (TAS2R) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 168.4 18.8 6.7e-53 2.9e-49 1 260 [] 81 345 .. 81 345 .. 0.92 Alignments for each domain: == domain 1 score: 168.4 bits; conditional E-value: 6.7e-53 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevl.....CklvtaldvvnltasillltaisiDRYlaIvkpl 91 gN+lV++v++++ ++rt+tn++++n+a+aD+l++l++ p ++ l e++w +g+ + C++v++ +++++ +s+l+l+ai++DR+ aI pl FUN_000891-T1 81 GNTLVVCVVFQSLRMRTVTNYLIVNMACADFLYTLVAGPPLVIMILEEENWAMGSRGrgiyfCQVVNVAQYILIPVSLLTLAAIAFDRFFAILIPL 176 8****************************************************876555555********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 92 kykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlrksak 185 k+ i tkr+ ++l++W+ +++++ p+++ + + ++e +C+ ++ +++ ++++yt+++++++f pl++i+v+y+ i+r+l+ +++ FUN_000891-T1 177 KR--IITKRVFNWILLAIWMTSAAIGAPMIYSLRIEIF---EGELRCYEEWTPafDDESAKRIYTIVSFAVVFCFPLFIITVLYTIICRHLWFMKM 267 *9..***************************9999999...89********98655555*********************************9999 PP xxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 keks......kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + + k+++++rk++k+l++vvvvf+ wlP+ +++ll ++ ++++ +++ ++ +l+l+ ++++lNP +Y FUN_000891-T1 268 PGEIgqeeshNFIKHRNSRRKVVKMLIAVVVVFLASWLPLSVANLLLYF---STDTYIPDSVYFTCLFLMRASCALNPAVY 345 87654444442333334455*****************************...****************************9 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.9 0.0 2.4e-24 1e-20 16 150 .. 529 668 .. 515 669 .. 0.82 Alignments for each domain: == domain 1 score: 74.9 bits; conditional E-value: 2.4e-24 Laminin_G_3 16 tsafTvsaWvkpdsapqssralvs...essgggyelgldsdgqlrftvnggngaeeavt.sgasvpagqWtHvavtyd..ggtlrlYvnGeevgss 105 + Tv+a++++++ +s +++++ + + g+++++++ + +f+ n ++ +++t g++vp+++WtH+a+tyd +g++++YvnGe+++ + FUN_000891-T1 529 REGVTVAAFINLKDIEGSRSVFDTigiSHQCGQFHFEVNYGSVRWFHRNETQHIVFSCTaEGKQVPKDKWTHIAGTYDsaTGKAKIYVNGELRNMT 624 6789*************999998897666677******7754444444544444444444999***************54456************* PP Laminin_G_3 106 tltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeei 150 + g l++++ + iG+ ++ ++p+ G ide+riyn+aL ++i FUN_000891-T1 625 IGEGLLSRDWLSRAGIGDHKA-ARPLMGFIDEFRIYNYALPKADI 668 *99999988888888999988.7******************9998 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.2 18.0 6.1e-16 2.6e-12 1 256 [. 75 359 .. 75 360 .. 0.70 Alignments for each domain: == domain 1 score: 47.2 bits; conditional E-value: 6.1e-16 7TM_GPCR_Srsx 1 lvvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelv.fvvllltgtql...kr....eeCFlliivyvfgltaqsvllLvigiDlli 88 ++v+liGN l+++++f++ ++r+ +++Li+ + ad l + + v++ l++++ +r C ++++ + + ++ + l +i++D+++ FUN_000891-T1 75 MMVSLIGNTLVVCVVFQSLRMRTVTNYLIVNMACADFLYTLVAGPpLVIMILEEENWamgSRgrgiYFCQVVNVAQYILIPVSLLTLAAIAFDRFF 170 589*********************************99876665505556665554311122222246777777777888888888889******* PP 7TM_GPCR_Srsx 89 avkfPirYrllskekYllillifpvlyssi..ilvlgflqrddetiivC..applalagkas.eiftlssliin.....vivllvylvliiilkkk 174 a+ +P++ r ++k+ + ill++ ++ ++i ++++ e + C + a+++++ +i+t+ s+++ i++++y ++ + l ++ FUN_000891-T1 171 AILIPLK-RIITKRVFNWILLAIWMTSAAIgaPMIYSLRIEIFEGELRCyeEWTPAFDDESAkRIYTIVSFAVVfcfplFIITVLYTIICRHLWFM 265 *****98.6666666555554444433332112333333333344455511445567666553555555544321111144555555555555555 PP 7TM_GPCR_Srsx 175 kek.............kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 k +++s +kv k l +vv+f+ +W+ +++n + l+++ ++ + ++ + +l+ s++ n V+ + s++Yr+ f+++ FUN_000891-T1 266 KMPgeigqeeshnfikHRNSRRKVVKMLIAVVVVFLASWLPLSVANLL-LYFSTDTYIPDSVYFTCLFLMRASCALNPAVYAIFSENYRQGFKRV 359 5547799999999**9999*********************99988866.56899999999********************************987 PP >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 3.5e-05 0.15 82 109 .. 595 622 .. 574 677 .. 0.77 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.5e-05 Pentaxin 82 avepvhiCasWesssGivelwvdGkplv 109 + +++hi +++s++G ++++v+G++ FUN_000891-T1 595 KDKWTHIAGTYDSATGKAKIYVNGELRN 622 349*********************7654 PP >> Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 9.6e-05 0.41 78 141 .. 557 625 .. 478 663 .. 0.62 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 9.6e-05 Toxin_R_bind_N 78 nnsG.Wkvslenneliftlidsngnekkivl......sdyi.nkWvfitisndrlknklliyingklvanes 141 ++G + ++++ + + +++++iv+ ++ +kW++i+ + d + k +iy+ng+l + + FUN_000891-T1 557 HQCGqFHFEVNYGSVRWF---HRNETQHIVFsctaegKQVPkDKWTHIAGTYDSATGKAKIYVNGELRNMTI 625 556645666666666654...2356677888788887566669***********************987554 PP >> TAS2R Taste receptor protein (TAS2R) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 15.9 0.00088 3.7 15 300 .. 73 361 .. 54 364 .. 0.65 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.00088 TAS2R 15 vefllgilgngfivlvncidwvkkrklssidliLlsLaisRilllwlilldsflivlspnlllssklleilslvwtflnelslWlatlLsvfYclK 110 + +++ ++gn+++v v + ++ ++ +++++++a + +l ++ ++++l + ++++ + + ++ +++n ++ l s + ++ FUN_000891-T1 73 LLMMVSLIGNTLVVCVVFQSLRMR---TVTNYLIVNMACADFLYTLVAGPPLVIMILEEENWAMGSRGRGI-YFCQVVNVAQYILI-PVSLLTLAA 163 445556666666666655544333...35567777777777777777777777777777777777777777.44455565554333.345555666 PP TAS2R 111 ianfs.hpvFLwLKwri.skvvlwlLLgsllisllllvkiikeikasidlellklkrnttlklkeeklellsslvllnlgvllpfivflisflLLi 204 ia + + + LK+ i ++v+ w+LL+ ++ s+++ + +i + + i+ l+ ++ t +++e+++++++ v + + +++p+ ++ + + + FUN_000891-T1 164 IAFDRfFAILIPLKRIItKRVFNWILLAIWMTSAAIGAPMIYSLRIEIFEGELRCYEEWTPAFDDESAKRIYTIVSFAVVFCFPLFIITVLYTIIC 259 6632213455567877636799************9999999999998888888**********************887777777777776666666 PP TAS2R 205 vSLw..rHtkkm....qlnstgsrdpsteahvkalkslisFllLyilyflsilisiislllpknkllliigeivallypslHsliLilgnskLkqa 294 Lw + + +n +r++++++ + ++++Fl ++ +++ l+ ++s+ ++++++ ++ + +l + + +++ +q FUN_000891-T1 260 RHLWfmKMPGEIgqeeSHNFIKHRNSRRKVVKMLIAVVVVFLASWLPLSVANLLLYFSTDTYIPDSVYFTCLFLMRASCALNPAVYAIFSENYRQG 355 666622222222211134444566666666666666666666666777777777777777777777888888888887777777777777777777 PP TAS2R 295 alkvll 300 +++vl FUN_000891-T1 356 FKRVLA 361 777775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (764 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1010 (0.0395381); expected 510.9 (0.02) Passed bias filter: 577 (0.0225876); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7305.83 // Query: FUN_000892-T1 [L=917] Description: FUN_000892 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-82 274.8 15.7 2e-22 80.4 0.1 4.4 4 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 6.8e-21 75.3 5.4 7.1e-06 26.3 0.1 5.1 4 Pentaxin Pentaxin family 7.5e-18 65.4 4.2 8.1e-05 22.9 0.1 4.5 4 Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor b 0.00054 20.0 1.6 19 5.2 0.0 4.6 4 Sialidase Sialidase, N-terminal domain Domain annotation for each model (and alignments): >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.8 0.0 5.1e-22 3.3e-18 18 150 .. 91 234 .. 76 235 .. 0.79 2 ! 70.6 1.8 3.4e-23 2.2e-19 7 151 .] 309 462 .. 303 462 .. 0.81 3 ! 64.2 1.3 3.1e-21 2e-17 18 150 .. 544 694 .. 526 695 .. 0.82 4 ! 80.4 0.1 3.2e-26 2e-22 7 150 .. 755 908 .. 749 909 .. 0.83 Alignments for each domain: == domain 1 score: 66.8 bits; conditional E-value: 5.1e-22 Laminin_G_3 18 afTvsaWvkpdsapqssralvs......essgg.....gyelgldsdgqlrf.tvnggngaeeavt.sgasvpagqWtHvavtyd..ggtlrlYvn 98 + Tv++ v+++++++++ +l++ +y l+++++ +lr+ + n ++++ +++ +g ++ g+W+H+a++yd g+ r+Y+n FUN_000892-T1 91 EVTVAMMVQLNEVSGKT-VLFEtiggppM---SihqepQYLLQVENA-RLRWfHRNENGSTVFSIItDGPVLSNGKWYHIAAMYDglRGSSRIYIN 181 5799999*******955.55543555552...044557999999887.55551555555566655515555566***********66699****** PP Laminin_G_3 99 GeevgsstltgaltkatggplyiGrdn.ggdspfdGlidevriynraLsaeei 150 G + ++ t +++ + + yiG gg+ ++ G+ide+ iyn++L++ e FUN_000892-T1 182 GRLSKQETADPGVFLSRDWSKYIGIGEfGGEGRLEGYIDELYIYNKTLTEPEL 234 *********999888899999999988799*******************9986 PP == domain 2 score: 70.6 bits; conditional E-value: 3.4e-23 Laminin_G_3 7 vtlpdasl...ttsafTvsaWvkpdsapqssralvs....essgg....gyelgldsdgqlrftvnggng.aeeavtsgasvpagqWtHvavtyd. 89 ++l+ +++ + +a T+++W++++s++++ ++++ + +y l +++ g ++++ n++n + ++vt++ v+++qW+Hva+ty+ FUN_000892-T1 309 IKLDGKTFrnkPIDAVTIALWINVTSVKGAHYLFDTigghS---AhkhdQYLLAINN-GAVTWSHNDQNDrQLFKVTTDPIVTENQWVHVAATYSm 400 5555555521135689*************888888786542...2345699999966.5555555555431667*********************9 PP Laminin_G_3 90 .ggtlrlYvnGeevgsstltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeeia 151 +g++++++nG++ ++++++g+l++++++ ++G+ g+ ++ d +dev +y+r+Ls+ ei+ FUN_000892-T1 401 qSGQAKIFINGNMNKQGPGSGRLSEDWDSYAAFGKHTGSVTDID-TLDEVYMYSRELSPFEIK 462 9999*********************************9989888.79************9995 PP == domain 3 score: 64.2 bits; conditional E-value: 3.1e-21 Laminin_G_3 18 afTvsaWvkpdsapqssralvs.....essgg.gyelgldsdgqlrftvnggngaeeavtsgasvpa.gqWtHvavtyd..ggtlrlYvnGeevgs 104 + T+ +W+k+d++ ++++++ + +++ +y +++ ++ +f+ n ++ + ++++++ +v + g+WtH+ +ty gg+ +YvnG+++++ FUN_000892-T1 544 GVTMGLWLKLDTNRGEQTIFSTcnpdnPWNSNvQYAFEIVDGRVKWFHENEKSQTVFSAETNTPVVPaGTWTHISCTYTaaGGKSEIYVNGVLKKE 639 57999**********99999988765544555899999977654455556665667777766666555***********87788*********999 PP Laminin_G_3 105 s.tltgaltkatggplyiGrdn.....gg...dspfdGlidevriynraLsaeei 150 t++g+l+++++g++ iG+++ g+ ++ + G ide+ +++raL ++ei FUN_000892-T1 640 EfTGAGTLSQDWAGKISIGKSYekavdGQwisQNKLYGIIDEFYLFDRALKQNEI 694 7588888999************998862255699999*****************9 PP == domain 4 score: 80.4 bits; conditional E-value: 3.2e-26 Laminin_G_3 7 vtlpdasl...ttsafTvsaWvkpdsapqssralvs.essgg....gyelgldsdgqlrf.tvnggngaeeavtsgasvpagqWtHvavtydggt. 92 +++p ++ + +a+++s+W+ ++++ ++ ++ + +s+++ +y + + ++ ++ + + + ++++ +++ + +pa +WtHv++tyd++ FUN_000892-T1 755 IEVPGDTFrerPQKAISISVWIDLQTNRGRHEIFNTiGSHSDhkhdQYDFAVKDG-KIIWyHHQENDKEVFSLITLPVIPARRWTHVVATYDSNAm 849 566665553324889**************99998878555555667999999775.555515555556777999******************9888 PP Laminin_G_3 93 .lrlYvnGeevgsstltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeei 150 ++++vnG++v++++ g+l++++g+ iGr +++++ Glide+ iyn+aLs +ei FUN_000892-T1 850 lAKVFVNGNLVKQKSAIGDLSQDWGHFAGIGRHFYEGTYLSGLIDEFIIYNYALSRKEI 908 9******************9999888888*****999*********************9 PP >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 2e-05 0.13 83 168 .. 160 239 .. 127 252 .. 0.87 2 ! 26.3 0.1 1.1e-09 7.1e-06 20 170 .. 317 468 .. 309 474 .. 0.77 3 ! 22.9 0.3 1.3e-08 8.3e-05 20 173 .. 538 704 .. 532 715 .. 0.69 4 ! 11.5 0.1 4e-05 0.26 74 167 .. 822 912 .. 761 916 .. 0.59 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2e-05 Pentaxin 83 vepvhiCasWesssGivelwvdGkplvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvyk 168 ++ hi a ++ G ++++G++ ++++ g+++ ++ s +G G+f + l+G + +l++++ L++ e+k + + FUN_000892-T1 160 GKWYHIAAMYDGLRGSSRIYINGRLSKQETADPGVFLSRDWSKYIGI------GEFGGEGRLEGYIDELYIYNKTLTEPELKLLIN 239 48**********************99999999999999999988885......67777899****************999987765 PP == domain 2 score: 26.3 bits; conditional E-value: 1.1e-09 Pentaxin 20 lekPLknltlClrfytd.Lsrsyslfs....yatkkkdnelLifkekdgeyslyvggeevlvkvseeav....epvhiCasWesssGivelwvdGk 106 +kP++++t+ l++ ++ +++++ lf ++++k+d lL + +s + +++++l+kv+ + ++vh+ a+++ sG ++++++G FUN_000892-T1 317 RNKPIDAVTIALWINVTsVKGAHYLFDtiggHSAHKHDQYLLAINNGAVTWSHNDQNDRQLFKVTTDPIvtenQWVHVAATYSMQSGQAKIFING- 411 589**********98776999**99963333688899999999********************99887777889*********************. PP Pentaxin 107 plvkkslkkgytvgaeasiilGqeqDsyG..GkfdksqslvGelsdlnlWdyvLspeeiktvykga 170 + k++ g l + Dsy Gk s + + l +++++ Lsp eik +y FUN_000892-T1 412 NMNKQGPGSG---------RLSEDWDSYAafGKHTGSVTDIDTLDEVYMYSRELSPFEIKALYDNC 468 3444443333.........35677788762233333333345567888888888888888888765 PP == domain 3 score: 22.9 bits; conditional E-value: 1.3e-08 Pentaxin 20 lekPLknltlClrfytdLs.rsyslfsyatkk...kdnelLifkekdgeyslyvgg.eevlvkvseeav......epvhiCasWesssGivelwvd 104 +kPL +t+ l+ + d + + + +fs ++n f dg + ++ + ++v e+++ +++hi ++ ++ G e++v+ FUN_000892-T1 538 KKKPLFGVTMGLWLKLDTNrGEQTIFSTCNPDnpwNSNVQYAFEIVDGRVKWFHENeKSQTVFSAETNTpvvpagTWTHISCTYTAAGGKSEIYVN 633 5899999999999999987356789987654433344444444444444433222202222222232224578889******************** PP Pentaxin 105 Gkplvkkslkkgytvga..easiilGqeqD.syGGkfdksqslvGelsdlnlWdyvLspeeiktvykgatls 173 G + + + + g t+ + +i +G+ + ++ G++ + l G + + +l+d +L+++ei+ + ++ + FUN_000892-T1 634 GVLKKEEFTGAG-TLSQdwAGKISIGKSYEkAVDGQWISQNKLYGIIDEFYLFDRALKQNEITLLAQTCNYH 704 *65555544444.444401456999998652799****************************9998876655 PP == domain 4 score: 11.5 bits; conditional E-value: 4e-05 Pentaxin 74 vlvkvseeav....epvhiCasWesssGivelwvdGkplvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeikt 165 ++ + v +++h+ a+++s +++++v+G+++++ks + + + +G +f + l G + + +++y+Ls +ei++ FUN_000892-T1 822 EVFSLITLPViparRWTHVVATYDSNAMLAKVFVNGNLVKQKSAIGDLSQ--DWGHF-----AGIGRHFYEGTYLSGLIDEFIIYNYALSRKEIEF 910 333333333345559*********************88887775433222..11112.....2334456666667777777777777777777776 PP Pentaxin 166 vy 167 + FUN_000892-T1 911 LA 912 65 PP >> Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.0 0.0001 0.67 111 179 .. 159 228 .. 128 229 .. 0.71 2 ! 22.9 0.1 1.3e-08 8.1e-05 28 139 .. 298 416 .. 294 421 .. 0.81 3 ! 8.0 0.1 0.00048 3 6 140 .. 496 640 .. 492 689 .. 0.66 4 ! 22.6 0.1 1.6e-08 0.0001 4 142 .. 720 865 .. 717 903 .. 0.71 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.0001 Toxin_R_bind_N 111 inkWvfitisndrlknklliyingklvanesiknllniyssnnIslklvrcadenk.svlieelsifnke 179 + kW++i+ d l+ + iying+l ++e + + + + + ++ e + + +i+el i+nk+ FUN_000892-T1 159 NGKWYHIAAMYDGLRGSSRIYINGRLSKQETADPGVFLSRDWSKYIGIGEFGGEGRlEGYIDELYIYNKT 228 369************************9998776333333333344456655544325677777777765 PP == domain 2 score: 22.9 bits; conditional E-value: 1.3e-08 Toxin_R_bind_N 28 nalklknseqsisfsnkilensltnnFsisfWlripkkdns...eskiIssk.knnsGWkvslenneliftlidsngnek.kivlsdyi..nkWv 115 n ++++ + i++ k++ n+ ++ +i W+ ++ ++ +i + +++ + + ++n+ + ++ +d n+ + k++ + n+Wv FUN_000892-T1 298 NGVQISAGQADIKLDGKTFRNKPIDAVTIALWINVTSVKGAhylFDTIGGHSaHKHDQYLLAINNGAVTWSHNDQNDRQLfKVTTDPIVteNQWV 392 556777778899************************999883322344444434555799**************99887526666555457**** PP Toxin_R_bind_N 116 fitisndrlknklliyingklvan 139 +++ + + + +i+ing+++++ FUN_000892-T1 393 HVAATYSMQSGQAKIFINGNMNKQ 416 *******999999*******9986 PP == domain 3 score: 8.0 bits; conditional E-value: 0.00048 Toxin_R_bind_N 6 DaSgknskievse..dielvy.innnalklknseqsisfsnkilensltnnFsisfWlripkkdnseskiIsskknnsGWkvslenneliftlid 97 D Sg +++ e+++ ++++++ + +n l+l + +i ++ ++++ + ++ Wl+ +++ e++i s+ + + W+ +++ f++ d FUN_000892-T1 496 DDSGSGNNGELTSlaTVTKTSgTCGNGLRLRGG--NILINGQLIKKKPLFGVTMGLWLKL-DTNRGEQTIFSTCNPDNPWNSNVQYA---FEIVD 584 555555555554411555555577777777765..4777788888888888899999996.56677799999998888897666554...55555 PP Toxin_R_bind_N 98 .......sngnekkivl......sdyi..nkWvfitisndrlknklliyingklvane 140 n++++ v+ + W++i+ + + k iy+ng+l+++e FUN_000892-T1 585 grvkwfhENEKSQ-TVFsaetntP-VVpaGTWTHISCTYTAAGGKSEIYVNGVLKKEE 640 2222211233333.3444666531.222478**********************98865 PP == domain 4 score: 22.6 bits; conditional E-value: 1.6e-08 Toxin_R_bind_N 4 ikDaSgknsk.ievsedielvyinnnalklknseq.sisfsnkilensltnnFsisfWlripkkdns..eskiIsskknns..GWkvslenneli 92 + D Sg +++ + ++++++ yin+ k n +i+++ +++ + + sis W+ + + + I+s +++ ++ ++++++i FUN_000892-T1 720 VYDQSGLANNgLALNGTVS--YINGTCGKSVNMTMgQIEVPGDTFRERPQKAISISVWIDLQTNRGRheIFNTIGSHSDHKhdQYDFAVKDGKII 812 5677776554145555554..4555554444444448999******************9765443332234556666555422589********* PP Toxin_R_bind_N 93 ftlidsngne..kkivlsdyi.nkWvfitisndrlknklliyingklvanesi 142 + ++ n++e + i+l + +W++++ + d ++++ng+lv+++s FUN_000892-T1 813 WYHHQENDKEvfSLITLPVIPaRRWTHVVATYDSNAMLAKVFVNGNLVKQKSA 865 *8877766653355677766589***********99999*********99974 PP >> Sialidase Sialidase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.0 0.0 0.0067 42 163 182 .. 216 235 .. 166 240 .. 0.81 2 ? 2.8 0.0 0.017 1.1e+02 54 127 .. 348 413 .. 304 423 .. 0.75 3 ! 5.2 0.0 0.003 19 115 182 .. 624 695 .. 573 701 .. 0.76 4 ? 3.1 0.1 0.013 81 108 182 .. 840 909 .. 786 914 .. 0.65 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.0067 Sialidase 163 kgsidelsvyNkalsdeevs 182 +g idel +yNk+l++ e++ FUN_000892-T1 216 EGYIDELYIYNKTLTEPELK 235 689************99875 PP == domain 2 score: 2.8 bits; conditional E-value: 0.017 Sialidase 54 SnskkkdeYFslfvrnsevglElRdskkeqnyqssrealvklkkdqknsatentvklkaelkdkryklyvNGvi 127 ++ k d+Y l++ n v+ d++++q ++ +++ + ++q+ +++ + ++ ++ k+++NG + FUN_000892-T1 348 HSAHKHDQY-LLAINNGAVTWSHNDQNDRQLFKVTTD--PIVTENQWVHVAAT-----YSMQSGQAKIFINGNM 413 455555555.5899999**************999999..44677778766543.....3345678999999944 PP == domain 3 score: 5.2 bits; conditional E-value: 0.003 Sialidase 115 kdkryklyvNGvieevsetsdkFikniedvdkatiGatnReg.keeylak....gsidelsvyNkalsdeevs 182 ++ ++yvNGv+++ + t +++ + k+ iG+ + + ++ ++ g ide+ ++ +al ++e+ FUN_000892-T1 624 AGGKSEIYVNGVLKKEEFTGAGTLSQ-DWAGKISIGKSYEKAvDGQWISQnklyGIIDEFYLFDRALKQNEIT 695 4577899******9998887666654.44569999*987666689998763333669999*******999986 PP == domain 4 score: 3.1 bits; conditional E-value: 0.013 Sialidase 108 vklkaelkdkryklyvNGvieevsetsdkFikniedvdkatiGatnRegkeeylakgsidelsvyNkalsdeevs 182 v+ + +++ k++vNG + + + i ++ + + G + + yl+ g ide+ +yN als +e++ FUN_000892-T1 840 VVATYDSNAMLAKVFVNGNLVKQKSA----IGDLSQDWGHFAGIGRHFYEGTYLS-GLIDEFIIYNYALSRKEIE 909 45566666777788888833333333....4444332222333333333445665.77999999**999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (917 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 589 (0.0230573); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.42u 0.41s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 8661.81 // Query: FUN_000893-T1 [L=115] Description: FUN_000893 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 342 (0.0133881); expected 510.9 (0.02) Passed bias filter: 285 (0.0111568); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1177.38 // Query: FUN_000894-T1 [L=357] Description: FUN_000894 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-33 115.7 0.4 2.8e-33 114.7 0.4 1.5 1 SH3_AEBP2_C AEBP2-like, C-terminal SH3 domain 3.4e-06 27.1 8.8 0.00026 21.1 1.3 3.8 4 Zap1_zf1 Zap1, C2H2 zinc finger 1 0.00051 20.7 1.1 0.59 10.7 0.4 2.5 2 zf-C2H2_aberr Aberrant zinc-finger 0.00077 20.2 3.1 0.0068 17.2 0.1 3.5 3 zf-H2C2_2 Zinc-finger double domain 0.0025 18.9 4.6 0.098 13.7 0.3 3.3 3 Zf-C2H2_ZNF451_C Two consecutive Zinc fingers C2H2 type, ZNF 0.0054 16.8 0.1 0.0054 16.8 0.1 2.5 3 zf_C2H2_ZNF292 Zinc finger protein 292, C2H2-type zinc fin ------ inclusion threshold ------ 0.038 14.0 1.3 0.15 12.1 0.0 2.7 2 zf-C2H2_5 C2H2-type zinc finger 0.088 13.7 4.0 16 6.4 0.6 2.9 3 zf-C2H2_8 C2H2-type zinc ribbon 0.1 13.6 9.4 0.14 13.2 0.6 3.5 3 FOXP-CC FOXP coiled-coil domain 0.16 12.6 0.2 0.16 12.6 0.2 2.2 2 zf_C2H2_17_1st C2H2-domain containing protein first zinc f 0.21 11.9 7.3 0.36 11.2 2.9 2.6 2 TSTD2_N TSTD2 protein N-terminal domain 0.63 11.1 0.1 0.63 11.1 0.1 4.6 3 zf-C2H2 Zinc finger, C2H2 type 5.4 8.2 11.1 2.8 9.1 1.7 3.1 3 zf-C2H2_3rep Zinc finger C2H2-type, 3 repeats 9.6 7.7 18.3 0.74 11.2 0.3 4.1 3 zf-C2H2_4 C2H2-type zinc finger Domain annotation for each model (and alignments): >> SH3_AEBP2_C AEBP2-like, C-terminal SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 114.7 0.4 1.5e-36 2.8e-33 2 123 .. 224 348 .. 223 350 .. 0.93 Alignments for each domain: == domain 1 score: 114.7 bits; conditional E-value: 1.5e-36 SH3_AEBP2_C 2 kllkkkkkklrlrrqpv..sarmfDFfDsgimeglqhrllkltektqlestgsgnsitfrsqviarRtee.sgekevllrWtPenilpDeWvpeke 94 kllk+kkkk+++ rq ++DF+ ++ + +++++l +++ +++++ +g++i+f+s+v++rRtee +g ++vllrW Pe+ilpDeWvp ++ FUN_000894-T1 224 KLLKRKKKKVKVLRQARppVQAKEDFINQHAVTKIKEKLPHVMPLSCYRLGIDGAKIVFQSKVLGRRTEEkNGDVDVLLRWVPEDILPDEWVPLND 319 8899********997651144559*********************************************999************************ PP SH3_AEBP2_C 95 vkekktkvVpisslpaetaaaleeslyra 123 v++++tk+V+is+lp++ aa+l++s+yr+ FUN_000894-T1 320 VQKHRTKTVHISQLPNDVAAELDPSFYRR 348 **************************986 PP >> Zap1_zf1 Zap1, C2H2 zinc finger 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 1.3 1.4e-07 0.00026 2 27 .] 113 138 .. 112 138 .. 0.96 2 ? 1.8 0.1 0.16 2.8e+02 2 8 .. 148 154 .. 147 157 .. 0.87 3 ! 6.8 0.0 0.0043 7.8 7 22 .. 186 201 .. 181 202 .. 0.93 4 ? -3.6 0.1 7.6 1.4e+04 15 21 .. 317 323 .. 317 323 .. 0.86 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 1.4e-07 Zap1_zf1 2 kCkWddCsesFsnlidLqkHvlkdHv 27 +CkW +C +F+n +L +Hv Hv FUN_000894-T1 113 ECKWISCHLTFQNTAELSEHVKTAHV 138 7*********************9998 PP == domain 2 score: 1.8 bits; conditional E-value: 0.16 Zap1_zf1 2 kCkWddC 8 C W C FUN_000894-T1 148 VCLWEGC 154 5****** PP == domain 3 score: 6.8 bits; conditional E-value: 0.0043 Zap1_zf1 7 dCsesFsnlidLqkHv 22 Cs +Fs+ + L +Hv FUN_000894-T1 186 GCSLTFSSREGLARHV 201 7**************9 PP == domain 4 score: -3.6 bits; conditional E-value: 7.6 Zap1_zf1 15 lidLqkH 21 l+d qkH FUN_000894-T1 317 LNDVQKH 323 6899**9 PP >> zf-C2H2_aberr Aberrant zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 0.4 0.00032 0.59 2 47 .. 113 156 .. 112 177 .. 0.75 2 ! 8.2 0.0 0.002 3.6 1 23 [. 180 202 .. 180 217 .. 0.89 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00032 zf-C2H2_aberr 2 kClykaCdlkyssvlglrrhlseykhslytndefslkCpvrkCsvs 47 C +++C+l+++++ l +h+++++ + ++ ++C + C+ + FUN_000894-T1 113 ECKWISCHLTFQNTAELSEHVKTAHV-EPMASQDVFVCLWEGCK-V 156 59*******************98755.55555577899999994.3 PP == domain 2 score: 8.2 bits; conditional E-value: 0.002 zf-C2H2_aberr 1 ykClykaCdlkyssvlglrrhls 23 +kC+ + C l++ss gl rh+ FUN_000894-T1 180 FKCMISGCSLTFSSREGLARHVP 202 8********************95 PP >> zf-H2C2_2 Zinc-finger double domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.4 7.4e+02 1 17 [. 128 149 .. 128 158 .. 0.71 2 ! 17.2 0.1 3.7e-06 0.0068 2 25 .. 167 192 .. 167 193 .. 0.84 3 ? -1.7 0.0 3.7 6.7e+03 2 12 .. 197 207 .. 196 210 .. 0.78 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.4 zf-H2C2_2 1 aLkrHmrt.Ht....gekpykC 17 +L +H++t H ++ + C FUN_000894-T1 128 ELSEHVKTaHVepmaSQDVFVC 149 5899****99755555555666 PP == domain 2 score: 17.2 bits; conditional E-value: 3.7e-06 zf-H2C2_2 2 LkrHmrtHtgekpykCp..eCgksFk 25 L +H+ +Htg kp+kC+ C+ +F+ FUN_000894-T1 167 LTKHVNIHTGAKPFKCMisGCSLTFS 192 678*************9666877776 PP == domain 3 score: -1.7 bits; conditional E-value: 3.7 zf-H2C2_2 2 LkrHmrtHtge 12 L rH+ +H ++ FUN_000894-T1 197 LARHVPSHFND 207 889*9888776 PP >> Zf-C2H2_ZNF451_C Two consecutive Zinc fingers C2H2 type, ZNF451 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.1 2.8 5e+03 26 47 .. 82 103 .. 48 110 .. 0.68 2 ! 13.7 0.3 5.4e-05 0.098 7 39 .. 118 149 .. 112 166 .. 0.72 3 ? 5.4 0.0 0.022 40 3 33 .. 180 212 .. 179 217 .. 0.78 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 2.8 Zf-C2H2_ZNF451_C 26 hsekkkeeeemyvvkCgaCska 47 ++++++++ + y+ k aC+ka FUN_000894-T1 82 KNNESSSSVSSYIEKRRACTKA 103 3334444455677777777776 PP == domain 2 score: 13.7 bits; conditional E-value: 5.4e-05 Zf-C2H2_ZNF451_C 7 lCsaTaQnladlnaHlekahsekkkeeeemyvv 39 +C T Qn+a+l++H+++ah e ++ ++ +v FUN_000894-T1 118 SCHLTFQNTAELSEHVKTAHVEPMAS-QDVFVC 149 7*****************99987553.445543 PP == domain 3 score: 5.4 bits; conditional E-value: 0.022 Zf-C2H2_ZNF451_C 3 FrCsl..CsaTaQnladlnaHlekahsekkkee 33 F+C++ Cs T + ++l +H+ ++ +++k + FUN_000894-T1 180 FKCMIsgCSLTFSSREGLARHVPSHFNDSKPAK 212 7886555***************99877655443 PP >> zf_C2H2_ZNF292 Zinc finger protein 292, C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.4 0.77 1.4e+03 16 44 .. 109 137 .. 94 147 .. 0.75 2 ? -2.6 0.3 3.2 5.9e+03 14 27 .. 142 155 .. 130 157 .. 0.75 3 ! 16.8 0.1 3e-06 0.0054 16 39 .. 177 200 .. 168 204 .. 0.90 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.77 zf_C2H2_ZNF292 16 rkqypCmvkgCssVvkserslirHYkklH 44 r+ C C +++ l H k+ H FUN_000894-T1 109 RTTVECKWISCHLTFQNTAELSEHVKTAH 137 56667999999999999999999998888 PP == domain 2 score: -2.6 bits; conditional E-value: 3.2 zf_C2H2_ZNF292 14 llrkqypCmvkgCs 27 +++ + C +gC+ FUN_000894-T1 142 ASQDVFVCLWEGCK 155 45677999999996 PP == domain 3 score: 16.8 bits; conditional E-value: 3e-06 zf_C2H2_ZNF292 16 rkqypCmvkgCssVvkserslirH 39 +k + Cm++gCs ++s + l rH FUN_000894-T1 177 AKPFKCMISGCSLTFSSREGLARH 200 577********************* PP >> zf-C2H2_5 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.3 1.3 2.3e+03 17 22 .] 129 134 .. 116 134 .. 0.61 2 ? 12.1 0.0 8.2e-05 0.15 7 21 .. 187 201 .. 185 202 .. 0.95 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.3 zf-C2H2_5 17 LSQHvk 22 LS Hvk FUN_000894-T1 129 LSEHVK 134 788886 PP == domain 2 score: 12.1 bits; conditional E-value: 8.2e-05 zf-C2H2_5 7 CSLAFSSQkFLSQHv 21 CSL FSS++ L +Hv FUN_000894-T1 187 CSLTFSSREGLARHV 201 **************9 PP >> zf-C2H2_8 C2H2-type zinc ribbon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.6 0.0088 16 23 65 .. 99 142 .. 84 175 .. 0.67 2 ? 6.2 0.1 0.01 19 2 26 .. 182 206 .. 181 216 .. 0.86 3 ? -1.5 0.0 2.5 4.6e+03 18 50 .. 233 265 .. 218 272 .. 0.76 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0088 zf-C2H2_8 23 thcpptqslegklfrcsalsctetfpsmqelvahskl.hykpnr 65 + + + + c +sc tf + el h k h +p FUN_000894-T1 99 ACTKAVTTKDRTTVECKWISCHLTFQNTAELSEHVKTaHVEPMA 142 44444445555677899999999999999999998752666644 PP == domain 2 score: 6.2 bits; conditional E-value: 0.01 zf-C2H2_8 2 csspgcclsfpsvrdlaqhlrthcp 26 c gc l+f s la+h+ +h FUN_000894-T1 182 CMISGCSLTFSSREGLARHVPSHFN 206 8889***************999975 PP == domain 3 score: -1.5 bits; conditional E-value: 2.5 zf-C2H2_8 18 aqhlrthcpptqslegklfrcsalsctetfpsm 50 + lr pp q+ e + + + e +p + FUN_000894-T1 233 VKVLRQARPPVQAKEDFINQHAVTKIKEKLPHV 265 567888999999999888777777777777765 PP >> FOXP-CC FOXP coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.6 7.7e-05 0.14 6 31 .. 113 138 .. 110 146 .. 0.91 2 ? 1.6 0.8 0.31 5.7e+02 6 27 .. 148 172 .. 144 176 .. 0.71 3 ? 2.1 0.0 0.22 4e+02 7 37 .. 182 211 .. 180 236 .. 0.78 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 7.7e-05 FOXP-CC 6 vCkWPgCekvledveeflkHlqseHs 31 CkW C ++++++e+ +H+++ H FUN_000894-T1 113 ECKWISCHLTFQNTAELSEHVKTAHV 138 6************************7 PP == domain 2 score: 1.6 bits; conditional E-value: 0.31 FOXP-CC 6 vCkWPgC...ekvledveeflkHlq 27 vC W gC +k +++ + kH++ FUN_000894-T1 148 VCLWEGCkvfDKPSLSHSWLTKHVN 172 8******333345667777777776 PP == domain 3 score: 2.1 bits; conditional E-value: 0.22 FOXP-CC 7 CkWPgCekvledveeflkHlqseHslddkst 37 C gC+ ++++ e + +H+ s H +d+k + FUN_000894-T1 182 CMISGCSLTFSSREGLARHVPS-HFNDSKPA 211 77789**************976.66666544 PP >> zf_C2H2_17_1st C2H2-domain containing protein first zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.6 3.7 6.8e+03 5 21 .. 114 129 .. 113 137 .. 0.64 2 ? 12.6 0.2 8.9e-05 0.16 1 24 [. 178 200 .. 178 200 .. 0.94 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 3.7 zf_C2H2_17_1st 5 CkvesCedaqFSStacL 21 Ck sC + F ta L FUN_000894-T1 114 CKWISCH-LTFQNTAEL 129 9999994.667777666 PP == domain 2 score: 12.6 bits; conditional E-value: 8.9e-05 zf_C2H2_17_1st 1 KPYrCkvesCedaqFSStacLLRH 24 KP++C ++ C+ + FSS L RH FUN_000894-T1 178 KPFKCMISGCS-LTFSSREGLARH 200 9*********7.88******9999 PP >> TSTD2_N TSTD2 protein N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 2.9 0.00019 0.36 18 58 .. 101 141 .. 83 155 .. 0.82 2 ? 2.3 0.1 0.12 2.2e+02 36 53 .. 187 204 .. 167 216 .. 0.85 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00019 TSTD2_N 18 skevpaaseeskeksWkCCgqtFkelssIHkHvAaqHaaei 58 +k v+++ +++ e++W C+ tF+++++ Hv + H + + FUN_000894-T1 101 TKAVTTKDRTTVECKWISCHLTFQNTAELSEHVKTAHVEPM 141 35556666667789***********************8765 PP == domain 2 score: 2.3 bits; conditional E-value: 0.12 TSTD2_N 36 CgqtFkelssIHkHvAaq 53 C+ tF+++ + +Hv ++ FUN_000894-T1 187 CSLTFSSREGLARHVPSH 204 9**************765 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.4 0.0021 3.8 2 23 .] 113 137 .. 112 137 .. 0.93 2 ? 2.2 0.4 0.24 4.3e+02 13 23 .] 164 174 .. 159 174 .. 0.91 3 ? 11.1 0.1 0.00035 0.63 1 20 [. 180 201 .. 180 204 .. 0.92 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0021 zf-C2H2 2 kCp..dCgksFsrksnLkrHlrt.H 23 +C+ C+ +F + +L H +t H FUN_000894-T1 113 ECKwiSCHLTFQNTAELSEHVKTaH 137 588889*****************99 PP == domain 2 score: 2.2 bits; conditional E-value: 0.24 zf-C2H2 13 ksnLkrHlrtH 23 s L++H ++H FUN_000894-T1 164 HSWLTKHVNIH 174 689******99 PP == domain 3 score: 11.1 bits; conditional E-value: 0.00035 zf-C2H2 1 ykCp..dCgksFsrksnLkrHl 20 +kC +C +Fs+++ L rH FUN_000894-T1 180 FKCMisGCSLTFSSREGLARHV 201 899999***************6 PP >> zf-C2H2_3rep Zinc finger C2H2-type, 3 repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.9 0.62 1.1e+03 63 98 .. 55 90 .. 43 103 .. 0.63 2 ? 9.1 1.7 0.0015 2.8 34 120 .. 115 200 .. 96 201 .. 0.77 3 ? 6.6 0.2 0.0094 17 32 87 .. 179 234 .. 161 263 .. 0.66 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.62 zf-C2H2_3rep 63 skaaqqkalsagedssqklelsnsalvennsenegg 98 s a ++ ++s + d+s + +s+s ++nn+ ++++ FUN_000894-T1 55 SLAVKNGTSSHSSDTSASVVNSKSRELKNNESSSSV 90 455555666666677777777777666665554443 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0015 zf-C2H2_3rep 34 qcipcgshfgnkeqlwlhvlsvhpvdfklskaaqqkalsagedssqklelsnsalvennsenegglrkfvcrf..cGlkfdllpdlGrh 120 + i c f n+ +l hv + h + + ++++ l g + k ls+s ++++ + ++g + f c c l f l rh FUN_000894-T1 115 KWISCHLTFQNTAELSEHVKTAHVEPMASQDVFV--CLWEGCKVFDKPSLSHSW-LTKHVNIHTGAKPFKCMIsgCSLTFSSREGLARH 200 44899******************99988877766..555666778888888774.4455666777888888764477888877777777 PP == domain 3 score: 6.6 bits; conditional E-value: 0.0094 zf-C2H2_3rep 32 llqci..pcgshfgnkeqlwlhvlsvhpvdfklskaaqqkalsagedssqklelsnsa 87 ++c+ c f++ e l hv s h +d k++k ++ + s+ ++ k ++ + + FUN_000894-T1 179 PFKCMisGCSLTFSSREGLARHVPS-HFNDSKPAKRQKTDNDSSPKKL-LKRKKKKVK 234 456652258889**********976.8888888888777665555433.333333333 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.5 0.0041 7.5 3 24 .] 114 137 .. 112 137 .. 0.87 2 ? 0.5 0.2 1.1 2.1e+03 12 23 .. 163 174 .. 147 175 .. 0.68 3 ? 11.2 0.3 0.0004 0.74 1 23 [. 180 204 .. 180 205 .. 0.88 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0041 zf-C2H2_4 3 Cpi..CgksFsskkaLrrHlkkhH 24 C++ C+ +F + +L+ H+k+ H FUN_000894-T1 114 CKWisCHLTFQNTAELSEHVKTAH 137 55555****************998 PP == domain 2 score: 0.5 bits; conditional E-value: 1.1 zf-C2H2_4 12 skkaLrrHlkkh 23 s++ L +H++ h FUN_000894-T1 163 SHSWLTKHVNIH 174 445589999988 PP == domain 3 score: 11.2 bits; conditional E-value: 0.0004 zf-C2H2_4 1 fkCpi..CgksFsskkaLrrHlkkh 23 fkC i C+ +Fss+++L rH+ +h FUN_000894-T1 180 FKCMIsgCSLTFSSREGLARHVPSH 204 6777777***************998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (357 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1249 (0.0488941); expected 510.9 (0.02) Passed bias filter: 528 (0.0206694); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3455.34 // Query: FUN_000895-T1 [L=290] Description: FUN_000895 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.4e-15 55.1 18.3 2.2e-07 30.8 0.2 3.4 3 zf-CCCH_10 ZAP-like CCCH zinc finger 1.1e-08 35.3 29.3 3e-05 24.4 3.5 4.1 3 zf_CCCH_4 Zinc finger domain 5.7e-08 33.4 4.2 3.9e-05 24.3 1.0 2.3 2 zf-CCCH_3 Zinc-finger containing family 1.7e-07 31.4 26.6 2.6e-06 27.7 1.2 3.8 3 zf-CCCH Zinc finger C-x8-C-x5-C-x3-H type (and simila 2.3e-07 30.9 24.9 1.1e-05 25.5 2.0 3.5 3 zf-CCCH_4 CCCH-type zinc finger 2e-06 28.6 28.5 6.1e-05 23.9 2.3 3.9 3 zf-CCCH_2 RNA-binding, Nab2-type zinc finger 6.3e-06 27.2 16.3 0.0015 19.5 0.2 4.1 4 Torus Torus domain 0.002 19.0 1.5 0.0035 18.3 1.5 1.3 1 ZapB Cell division protein ZapB 0.0025 17.9 13.1 0.61 10.3 0.4 3.5 3 zf-CCCH_12 CCCH zinc finger domain 0.0033 18.1 14.7 1.4 9.7 1.4 3.2 3 zf-CCCH_PARP12 PARP12-like CCCH zinc finger tandem 0.0084 16.6 8.3 2.7 8.6 0.3 3.5 3 zf-CCCH_RBM22 RBM22 CCCH zinc finger domain ------ inclusion threshold ------ 0.02 15.9 0.0 0.035 15.1 0.0 1.3 1 NUDE_C NUDE protein, C-terminal conserved region 0.041 12.2 0.3 0.054 11.8 0.3 1.1 1 CCDC39 Coiled-coil domain-containing protein 39 0.064 13.7 0.3 0.1 13.0 0.3 1.2 1 Phage_scaffold Phage capsid assembly scaffolding protein 0.081 13.7 0.2 0.081 13.7 0.2 1.7 1 TPR Nucleoprotein TPR-like domain 0.12 13.0 1.4 0.25 12.0 0.5 1.6 1 bZIP_1 bZIP transcription factor 0.12 13.0 0.6 0.23 12.2 0.6 1.4 1 TSC22 TSC-22/dip/bun family 0.14 12.5 1.1 0.27 11.5 1.1 1.4 1 DivIC Septum formation initiator 0.16 12.4 16.3 0.26 11.7 0.7 3.4 3 zf-CCCH_DUS3L DUS3L CCCH zinc finger domain 0.29 11.8 3.5 1.1 9.9 0.6 2.3 2 HALZ Homeobox associated leucine zipper 0.41 11.3 3.2 0.65 10.6 3.2 1.3 1 Cep57_CLD_2 Centrosome localisation domain of PPC89 1 9.9 5.6 1.5 9.4 3.7 2.0 2 bZIP_2 Basic region leucine zipper 7.9 7.1 12.6 11 6.7 0.6 3.2 3 zf-CCCH_tandem Tandem CCCH zinc finger domains Domain annotation for each model (and alignments): >> zf-CCCH_10 ZAP-like CCCH zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 2.3 5.3e-06 0.0059 5 24 .. 29 49 .. 26 51 .. 0.91 2 ! 30.8 0.2 1.9e-10 2.2e-07 1 23 [. 58 80 .. 58 83 .. 0.95 3 ! 15.9 3.5 8.3e-06 0.0092 5 25 .. 118 139 .. 117 144 .. 0.89 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 5.3e-06 zf-CCCH_10 5 vCmDfiKgRCtRek.CkYfHP 24 +C+D+ +g CtR Ck+ HP FUN_000895-T1 29 ICRDYQRGVCTRGPkCKFQHP 49 8***********766****** PP == domain 2 score: 30.8 bits; conditional E-value: 1.9e-10 zf-CCCH_10 1 gkVtvCmDfiKgRCtRekCkYfH 23 +++++C+Df g+C+R +CkY+H FUN_000895-T1 58 NSPMICRDFQNGKCQRSSCKYLH 80 6789******************* PP == domain 3 score: 15.9 bits; conditional E-value: 8.3e-06 zf-CCCH_10 5 vCmDfiKgRCtRek.CkYfHPp 25 +C D++ +C R + C+Y+H + FUN_000895-T1 118 ICKDYLNRKCGRGQgCRYRHVS 139 8*******************55 PP >> zf_CCCH_4 Zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 3.5 2.7e-08 3e-05 1 19 [] 30 48 .. 30 48 .. 0.99 2 ! 10.4 2.7 0.0007 0.78 1 19 [] 63 80 .. 63 80 .. 0.94 3 ! 10.7 7.4 0.00056 0.63 1 19 [] 119 137 .. 119 137 .. 0.99 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 2.7e-08 zf_CCCH_4 1 CkfflkGrCryGdkCrFaH 19 C+++++G C++G kC+F H FUN_000895-T1 30 CRDYQRGVCTRGPKCKFQH 48 ******************9 PP == domain 2 score: 10.4 bits; conditional E-value: 0.0007 zf_CCCH_4 1 CkfflkGrCryGdkCrFaH 19 C++f++G+C++ ++C+++H FUN_000895-T1 63 CRDFQNGKCQR-SSCKYLH 80 ***********.7899999 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00056 zf_CCCH_4 1 CkfflkGrCryGdkCrFaH 19 Ck++l+ +C +G Cr++H FUN_000895-T1 119 CKDYLNRKCGRGQGCRYRH 137 ******************* PP >> zf-CCCH_3 Zinc-finger containing family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 1.0 3.5e-08 3.9e-05 8 56 .. 30 82 .. 23 90 .. 0.79 2 ! 10.0 0.1 0.00098 1.1 24 79 .. 105 162 .. 98 192 .. 0.79 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 3.5e-08 zf-CCCH_3 8 cyffyystctkGdscpfrheeaalGse.....tvctlwqegrclrevckfrhme 56 c + ct+G +c f+h + +G+e +c +q+g+c r+ ck+ h+ FUN_000895-T1 30 CRDYQRGVCTRGPKCKFQHPD-GMGTEltnspMICRDFQNGKCQRSSCKYLHLS 82 77788899***********76.567663333358******************86 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00098 zf-CCCH_3 24 frheeaalG.setvctlwqegrclr.evckfrhmelkkkrkeipcywenqpaGcqklh 79 +r e + G ++ +c+ + + +c r + c++rh+ + + + y + p G ++ + FUN_000895-T1 105 YRGESTRAGpNDPICKDYLNRKCGRgQGCRYRHVSEDMHDADYGGYCYEGPYGKRRRE 162 6666555553778999999999987467999999999999999999989998887765 PP >> zf-CCCH Zinc finger C-x8-C-x5-C-x3-H type (and similar) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 1.2 2.3e-09 2.6e-06 4 26 .. 28 49 .. 26 50 .. 0.93 2 ! 15.2 1.6 2e-05 0.022 5 25 .. 62 80 .. 62 82 .. 0.94 3 ? 6.5 1.6 0.011 12 4 26 .. 117 138 .. 114 139 .. 0.90 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 2.3e-09 zf-CCCH 4 elCrfflrtGyCkyGdrCkFaHg 26 ++Cr+++r G C +G++CkF H+ FUN_000895-T1 28 SICRDYQR-GVCTRGPKCKFQHP 49 58******.*************8 PP == domain 2 score: 15.2 bits; conditional E-value: 2e-05 zf-CCCH 5 lCrfflrtGyCkyGdrCkFaH 25 +Cr+f+ G C++ ++Ck+ H FUN_000895-T1 62 ICRDFQN-GKCQR-SSCKYLH 80 5******.*****.******* PP == domain 3 score: 6.5 bits; conditional E-value: 0.011 zf-CCCH 4 elCrfflrtGyCkyGdrCkFaHg 26 ++C+++l C +G C++ H+ FUN_000895-T1 117 PICKDYLN-RKCGRGQGCRYRHV 138 79******.**********9885 PP >> zf-CCCH_4 CCCH-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 2.0 1e-08 1.1e-05 2 22 .] 29 49 .. 28 49 .. 0.96 2 ! 7.8 2.9 0.0036 4 2 21 .. 62 80 .. 61 80 .. 0.91 3 ! 9.0 4.6 0.0016 1.7 1 21 [. 117 137 .. 117 137 .. 0.97 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1e-08 zf-CCCH_4 2 lCryfakGrCrfGdnCrFsHD 22 +Cr +++G C++G++C+F H+ FUN_000895-T1 29 ICRDYQRGVCTRGPKCKFQHP 49 7*******************7 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0036 zf-CCCH_4 2 lCryfakGrCrfGdnCrFsH 21 +Cr f++G+C + ++C+++H FUN_000895-T1 62 ICRDFQNGKCQR-SSCKYLH 80 7*********99.8999988 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0016 zf-CCCH_4 1 rlCryfakGrCrfGdnCrFsH 21 ++C+ + + +C +G Cr++H FUN_000895-T1 117 PICKDYLNRKCGRGQGCRYRH 137 79******************* PP >> zf-CCCH_2 RNA-binding, Nab2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 2.3 5.5e-08 6.1e-05 1 19 [] 29 49 .. 29 49 .. 0.97 2 ! 16.3 1.3 1.3e-05 0.015 1 18 [. 62 80 .. 62 80 .. 0.97 3 ? 5.7 2.9 0.03 34 1 18 [. 118 137 .. 118 137 .. 0.88 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 5.5e-08 zf-CCCH_2 1 pCrfg..gnCtfgpkCpFsHP 19 +Cr++ g Ct gpkC+F HP FUN_000895-T1 29 ICRDYqrGVCTRGPKCKFQHP 49 6****9999***********9 PP == domain 2 score: 16.3 bits; conditional E-value: 1.3e-05 zf-CCCH_2 1 pCrfg..gnCtfgpkCpFsH 18 +Cr++ g+C +++C+++H FUN_000895-T1 62 ICRDFqnGKCQ-RSSCKYLH 80 7*****99***.******** PP == domain 3 score: 5.7 bits; conditional E-value: 0.03 zf-CCCH_2 1 pCrfg.gn.CtfgpkCpFsH 18 +C+++ + C g C+++H FUN_000895-T1 118 ICKDYlNRkCGRGQGCRYRH 137 6****7646*********** PP >> Torus Torus domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.2 1.4e-06 0.0015 59 91 .. 16 48 .. 5 51 .. 0.84 2 ! 9.4 0.3 0.0019 2.2 68 97 .. 58 86 .. 50 96 .. 0.78 3 ! 7.8 0.4 0.0061 6.8 62 92 .. 110 138 .. 90 148 .. 0.82 4 ? -0.1 0.4 1.7 1.9e+03 7 35 .. 208 236 .. 179 281 .. 0.57 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 1.4e-06 Torus 59 sGytkadkekesyfClyFarGlCakGkkCeylH 91 + + k++++ + +C + rG+C++G kC++ H FUN_000895-T1 16 NSTDKSSENIQDSICRDYQRGVCTRGPKCKFQH 48 445577788889********************9 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0019 Torus 68 kesyfClyFarGlCakGkkCeylHrlPtee 97 ++ ++C F G C++ ++C+ylH +ee FUN_000895-T1 58 NSPMICRDFQNGKCQR-SSCKYLHLSNSEE 86 45699*********87.78*****765555 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0061 Torus 62 tkadkekesyfClyFarGlCakGkkCeylHr 92 t+a + +C + C +G+ C+y H FUN_000895-T1 110 TRAG--PNDPICKDYLNRKCGRGQGCRYRHV 138 4444..56899*******************6 PP == domain 4 score: -0.1 bits; conditional E-value: 1.7 Torus 7 rkqvdeeelkkekeeqegeeyNiwynkws 35 r q+ e++ ++ ++++ + y y s FUN_000895-T1 208 RNQIGERSSYNSGASANTTGYTTSYGATS 236 33333333333333333333333343333 PP >> ZapB Cell division protein ZapB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 1.5 3.1e-06 0.0035 14 54 .. 170 210 .. 167 217 .. 0.89 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 3.1e-06 ZapB 14 qaavdtielLkmeveeLkekneelaeeaeeleeenqqlkee 54 +vd+ e+L+++v+eL+++++ l+ +e l e+n + +++ FUN_000895-T1 170 YHLVDENESLRRKVAELQKQVTDLKATNEVLLEQNAKYRNQ 210 5799999************************9**9999875 PP >> zf-CCCH_12 CCCH zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.4 0.00055 0.61 9 27 .. 30 48 .. 26 50 .. 0.87 2 ? 5.8 0.7 0.014 15 15 27 .. 68 80 .. 62 81 .. 0.89 3 ! 8.9 0.7 0.0015 1.6 13 27 .. 122 137 .. 113 139 .. 0.95 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00055 zf-CCCH_12 9 CNnyHLrGsCengd.CeYdH 27 C+ y+ rG C++g C+++H FUN_000895-T1 30 CRDYQ-RGVCTRGPkCKFQH 48 66666.9************* PP == domain 2 score: 5.8 bits; conditional E-value: 0.014 zf-CCCH_12 15 rGsCengdCeYdH 27 +G+C + +C+Y H FUN_000895-T1 68 NGKCQRSSCKYLH 80 69*********98 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0015 zf-CCCH_12 13 HLrGsCengd.CeYdH 27 +L+ +C +g+ C Y H FUN_000895-T1 122 YLNRKCGRGQgCRYRH 137 8**************9 PP >> zf-CCCH_PARP12 PARP12-like CCCH zinc finger tandem # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.4 0.0082 9.1 16 37 .. 29 48 .. 28 49 .. 0.93 2 ! 9.7 1.4 0.0013 1.4 16 42 .. 62 85 .. 61 87 .. 0.86 3 ! 9.6 0.8 0.0013 1.4 16 37 .. 118 137 .. 117 143 .. 0.90 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0082 zf-CCCH_PARP12 16 LCklfllgkCrfkgrrkCkfsH 37 +C+ + g C+ kCkf H FUN_000895-T1 29 ICRDYQRGVCTR--GPKCKFQH 48 6*********87..9******9 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0013 zf-CCCH_PARP12 16 LCklfllgkCrfkgrrkCkfsHdlkse 42 +C+ f gkC+ ++Ck+ H +se FUN_000895-T1 62 ICRDFQNGKCQR---SSCKYLHLSNSE 85 69********65...*******87776 PP == domain 3 score: 9.6 bits; conditional E-value: 0.0013 zf-CCCH_PARP12 16 LCklfllgkCrfkgrrkCkfsH 37 +Ck +l kC ++C++ H FUN_000895-T1 118 ICKDYLNRKCGR--GQGCRYRH 137 7*********87..9******* PP >> zf-CCCH_RBM22 RBM22 CCCH zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.2 0.021 23 6 23 .. 29 46 .. 26 50 .. 0.89 2 ? 5.6 0.1 0.021 23 2 23 .. 58 78 .. 57 84 .. 0.86 3 ! 8.6 0.3 0.0025 2.7 6 24 .. 118 136 .. 114 143 .. 0.88 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.021 zf-CCCH_RBM22 6 iCSFWlkGECkRaEeCPY 23 iC + +G C R+ C + FUN_000895-T1 29 ICRDYQRGVCTRGPKCKF 46 999999**********76 PP == domain 2 score: 5.6 bits; conditional E-value: 0.021 zf-CCCH_RBM22 2 NRPriCSFWlkGECkRaEeCPY 23 N P iC + G C+R+ C Y FUN_000895-T1 58 NSPMICRDFQNGKCQRS-SCKY 78 89**************7.4766 PP == domain 3 score: 8.6 bits; conditional E-value: 0.0025 zf-CCCH_RBM22 6 iCSFWlkGECkRaEeCPYR 24 iC +l C R+ C YR FUN_000895-T1 118 ICKDYLNRKCGRGQGCRYR 136 9999999************ PP >> NUDE_C NUDE protein, C-terminal conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.0 3.1e-05 0.035 28 105 .. 174 252 .. 171 288 .. 0.55 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 3.1e-05 NUDE_C 28 qErEsLrievQRLrDElsDLkvEleivqeklrkaerrkkslplleteksdsapqasesldrsPvak.ttssplistppa 105 +E EsLr +v L+ + DLk +e+ e++ k +++ + ++ ++ s++++ + s ++ ++ +ts p+ +a FUN_000895-T1 174 DENESLRRKVAELQKQVTDLKATNEVLLEQNAKYRNQIGERSSYNSGASANTTGYTTSYGATSSQSySTSYPTQDSYTA 252 79**************************999877744444444344444444433333333332220222222222122 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.3 4.8e-05 0.054 459 497 .. 173 211 .. 159 224 .. 0.84 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 4.8e-05 CCDC39 459 eeekeelekkieeLeeeldekkktqnlLqsqikkleeel 497 +e+e l++k++eL++++++ k+t++ L +q k ++++ FUN_000895-T1 173 VDENESLRRKVAELQKQVTDLKATNEVLLEQNAKYRNQI 211 578999999999999999999999999999999988876 PP >> Phage_scaffold Phage capsid assembly scaffolding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.3 9.2e-05 0.1 36 79 .. 169 211 .. 157 230 .. 0.80 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 9.2e-05 Phage_scaffold 36 ldklkeekkelkkqlkeadkqleelkkkdneelkkkieelqekn 79 + l +e+++l+++++e +kq+++lk+ ne l ++ +++++++ FUN_000895-T1 169 YYHLVDENESLRRKVAELQKQVTDLKAT-NEVLLEQNAKYRNQI 211 5667899999999999999999999655.888888888888887 PP >> TPR Nucleoprotein TPR-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.2 7.3e-05 0.081 8 60 .. 175 227 .. 167 244 .. 0.60 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 7.3e-05 TPR 8 klerlerenerlqqqlrDLsrQVqvLlkeveelrgglgslereeleelargee 60 + e+l+r++ lq+q++DL+ +vLl + ++ r++ g++++ + a+++ FUN_000895-T1 175 ENESLRRKVAELQKQVTDLKATNEVLLEQNAKYRNQIGERSSYNSGASANTTG 227 44566677777777777777777777777777777777654444444444433 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.5 0.00023 0.25 38 63 .. 172 197 .. 167 198 .. 0.91 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00023 bZIP_1 38 LekeNksLkseleelkkevekLkskv 63 L eN+sL+ ++ el+k+v Lk + FUN_000895-T1 172 LVDENESLRRKVAELQKQVTDLKATN 197 899*******************9877 PP >> TSC22 TSC-22/dip/bun family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.6 0.0002 0.23 14 41 .. 174 201 .. 170 212 .. 0.83 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0002 TSC22 14 EeVevLkekIaeLeeriseleeENsiLr 41 +e e L+ k+aeL++++ l++ N++L FUN_000895-T1 174 DENESLRRKVAELQKQVTDLKATNEVLL 201 6779999999999999999999999874 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 1.1 0.00024 0.27 20 49 .. 177 206 .. 166 213 .. 0.57 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00024 DivIC 20 kqlkqeiaeleaeiaklkaeneeLeaeikd 49 +l++++ael++++ lka ne L ++ ++ FUN_000895-T1 177 ESLRRKVAELQKQVTDLKATNEVLLEQNAK 206 345555555555555555555555555444 PP >> zf-CCCH_DUS3L DUS3L CCCH zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.7 0.00024 0.26 8 24 .. 33 48 .. 24 48 .. 0.79 2 ? 6.5 0.8 0.011 12 5 24 .. 63 80 .. 59 80 .. 0.79 3 ? 3.0 2.0 0.13 1.4e+02 13 24 .. 125 137 .. 115 137 .. 0.80 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00024 zf-CCCH_DUS3L 8 fatsgkCpyGdkCRfsH 24 + g C +G kC+f H FUN_000895-T1 33 YQR-GVCTRGPKCKFQH 48 555.9**********77 PP == domain 2 score: 6.5 bits; conditional E-value: 0.011 zf-CCCH_DUS3L 5 CpsfatsgkCpyGdkCRfsH 24 C f gkC++ C+++H FUN_000895-T1 63 CRDFQN-GKCQRSS-CKYLH 80 555555.*******.***99 PP == domain 3 score: 3.0 bits; conditional E-value: 0.13 zf-CCCH_DUS3L 13 k.CpyGdkCRfsH 24 + C +G CR+ H FUN_000895-T1 125 RkCGRGQGCRYRH 137 5599*******87 PP >> HALZ Homeobox associated leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.6 0.001 1.1 13 39 .. 168 194 .. 161 196 .. 0.63 2 ? 5.4 0.7 0.026 29 10 35 .. 186 211 .. 186 213 .. 0.87 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.001 HALZ 13 sYdsLksdfdsLkkenqkLkaElqeLk 39 sY L +++sL++ L++++ Lk FUN_000895-T1 168 SYYHLVDENESLRRKVAELQKQVTDLK 194 555566666666666666666666666 PP == domain 2 score: 5.4 bits; conditional E-value: 0.026 HALZ 10 LKasYdsLksdfdsLkkenqkLkaEl 35 L+++ +Lk+ ++ L+++n k ++++ FUN_000895-T1 186 LQKQVTDLKATNEVLLEQNAKYRNQI 211 7888889************9988876 PP >> Cep57_CLD_2 Centrosome localisation domain of PPC89 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 3.2 0.00058 0.65 25 66 .. 168 209 .. 158 210 .. 0.86 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00058 Cep57_CLD_2 25 elkrLrrERDsalrqLgvAyleiqeLkaenealrkElkeqra 66 + +L E++s +r+ + +++Lka ne+l +++ +r FUN_000895-T1 168 SYYHLVDENESLRRKVAELQKQVTDLKATNEVLLEQNAKYRN 209 567999******************************999886 PP >> bZIP_2 Basic region leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.9 0.01 12 36 54 .] 171 189 .. 158 189 .. 0.79 2 ? 9.4 3.7 0.0014 1.5 24 53 .. 180 209 .. 177 210 .. 0.90 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.01 bZIP_2 36 eLekeNarLrqkveqleke 54 +L eN+ Lr+kv++l+k+ FUN_000895-T1 171 HLVDENESLRRKVAELQKQ 189 6789************986 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0014 bZIP_2 24 kqkeeeleervkeLekeNarLrqkveqlek 53 + k +el+++v +L++ N+ L+++ +++++ FUN_000895-T1 180 RRKVAELQKQVTDLKATNEVLLEQNAKYRN 209 67889********************99886 PP >> zf-CCCH_tandem Tandem CCCH zinc finger domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.6 0.01 11 28 42 .. 30 47 .. 28 52 .. 0.73 2 ? 2.1 0.6 0.27 3e+02 14 25 .. 68 79 .. 61 85 .. 0.54 3 ? 5.3 0.5 0.026 29 28 49 .. 119 146 .. 118 148 .. 0.72 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.01 zf-CCCH_tandem 28 Cp...kdg.CkagkkCkFp 42 C+ + g C++g+kCkF+ FUN_000895-T1 30 CRdyqR-GvCTRGPKCKFQ 47 886423.26*********5 PP == domain 2 score: 2.1 bits; conditional E-value: 0.27 zf-CCCH_tandem 14 gsaCrdadCiyG 25 +++C++ +C y FUN_000895-T1 68 NGKCQRSSCKYL 79 344555555444 PP == domain 3 score: 5.3 bits; conditional E-value: 0.026 zf-CCCH_tandem 28 Cp...kdgCkagkkCkF...pkemHgvd 49 C+ + +C +g+ C++ +++mH+ d FUN_000895-T1 119 CKdylNRKCGRGQGCRYrhvSEDMHDAD 146 7777766799999999832246888877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (290 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1629 (0.0637698); expected 510.9 (0.02) Passed bias filter: 883 (0.0345665); expected 510.9 (0.02) Passed Vit filter: 178 (0.0069681); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 23 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 2793.25 // Query: FUN_000896-T1 [L=716] Description: FUN_000896 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-22 78.4 0.0 1.6e-21 77.1 0.0 1.7 2 DBB Dof, BCAP, and BANK (DBB) motif, 0.007 17.4 0.0 0.017 16.1 0.0 1.6 1 Ank_2 Ankyrin repeats (3 copies) ------ inclusion threshold ------ 0.022 15.6 0.0 0.054 14.4 0.0 1.6 1 Ank_5 Ankyrin repeats (many copies) 0.043 14.9 0.4 0.16 13.1 0.1 2.2 2 Ank_3 Ankyrin repeat Domain annotation for each model (and alignments): >> DBB Dof, BCAP, and BANK (DBB) motif, # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.1 0.0 2.5e-25 1.6e-21 2 139 .. 17 155 .. 16 156 .. 0.93 2 ? -2.8 0.1 1.2 7.6e+03 86 102 .. 589 605 .. 588 606 .. 0.86 Alignments for each domain: == domain 1 score: 77.1 bits; conditional E-value: 2.5e-25 DBB 2 vlPkrvkcgkqnkvfilLkeklk...kedkvevefekenekikrvkvklrneytlqvkapedllsglvsvtvekgglslgerqvkyysrleeieql 94 +lP++v+ + ++++ i++ ++l+ +++ +vef + +++v++ l n+ tl +++pe + +v+v+v++g+ +lg++ ++ sr + +l FUN_000896-T1 17 ILPDKVEHNCKERIAIIFDHRLNvhkSKEAFKVEFVGSA-GSVQVSAVLANSSTLILETPEYKKACVVTVNVYHGNNMLGQHRFEFTSRSDSLYRL 111 89****************9988522255669******99.99******************7777******************************** PP DBB 95 LksaadPvefmCqalkissvdkekLDklLteslkknipasgfqll 139 L a dP+ fmC al+is+ + ++LD+ L+ ++++ p + f+ l FUN_000896-T1 112 LYGALDPISFMCEALQISPPELHELDHSLAVTFQTKAPHG-FEFL 155 *************************************998.8876 PP == domain 2 score: -2.8 bits; conditional E-value: 1.2 DBB 86 srleeieqlLksaadPv 102 s +eei+++L+s+++P FUN_000896-T1 589 SPVEEIQAMLNSQEQPA 605 5689********99996 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 2.7e-06 0.017 19 74 .. 162 220 .. 143 229 .. 0.74 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 2.7e-06 Ank_2 19 gadanlqdkngetaLhlAaknghleivklLle....hg.advndnngrtaLhyAaesghle 74 ga++ d++ t Lh+A+k+g ++++++Ll h+ +++++ +g+ + +A g e FUN_000896-T1 162 GAEK--SDSEHPTLLHFACKYGLTNLCQVLLTypgaHEaCSLKNYEGQRPYNLAQNLGFRE 220 3333..366889*******************966655534444799999999996556655 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 8.5e-06 0.054 18 56 .] 172 213 .. 162 213 .. 0.81 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 8.5e-06 Ank_5 18 tpLhvAakygaleivrlLl...angvdlnlkdeegltpldlA 56 t Lh+A+kyg ++ ++Ll ++++ lk+ eg+ p+ lA FUN_000896-T1 172 TLLHFACKYGLTNLCQVLLtypGAHEACSLKNYEGQRPYNLA 213 89*****************77777778888877777666665 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.1 2.5e-05 0.16 4 27 .. 172 195 .. 169 200 .. 0.89 2 ? -3.9 0.0 4 2.6e+04 14 23 .. 455 464 .. 454 466 .. 0.76 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2.5e-05 Ank_3 4 tpLhlAarngrleivklLleklga 27 t+Lh+A+++g ++++Ll +ga FUN_000896-T1 172 TLLHFACKYGLTNLCQVLLTYPGA 195 9******************97766 PP == domain 2 score: -3.9 bits; conditional E-value: 4 Ank_3 14 rleivklLle 23 r ++++Ll+ FUN_000896-T1 455 RKNMLQMLLN 464 5569999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (716 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 658 (0.0257585); expected 510.9 (0.02) Passed bias filter: 483 (0.0189078); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 7103.38 // Query: FUN_000896-T2 [L=540] Description: FUN_000896 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-22 78.5 0.0 9.9e-22 77.8 0.0 1.3 1 DBB Dof, BCAP, and BANK (DBB) motif, 0.0047 18.0 0.0 0.012 16.7 0.0 1.6 1 Ank_2 Ankyrin repeats (3 copies) ------ inclusion threshold ------ 0.014 16.2 0.0 0.037 14.9 0.0 1.7 1 Ank_5 Ankyrin repeats (many copies) 0.034 15.2 0.4 0.12 13.5 0.1 2.1 2 Ank_3 Ankyrin repeat 0.3 12.0 0.5 0.99 10.4 0.2 2.0 2 Ank Ankyrin repeat 0.81 10.2 2.6 6.5 7.3 0.3 2.4 2 DUF6788 Domain of unknown function (DUF6788) Domain annotation for each model (and alignments): >> DBB Dof, BCAP, and BANK (DBB) motif, # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.8 0.0 2.3e-25 9.9e-22 2 139 .. 17 155 .. 16 156 .. 0.93 Alignments for each domain: == domain 1 score: 77.8 bits; conditional E-value: 2.3e-25 DBB 2 vlPkrvkcgkqnkvfilLkeklk...kedkvevefekenekikrvkvklrneytlqvkapedllsglvsvtvekgglslgerqvkyysrleeieql 94 +lP++v+ + ++++ i++ ++l+ +++ +vef + +++v++ l n+ tl +++pe + +v+v+v++g+ +lg++ ++ sr + +l FUN_000896-T2 17 ILPDKVEHNCKERIAIIFDHRLNvhkSKEAFKVEFVGSA-GSVQVSAVLANSSTLILETPEYKKACVVTVNVYHGNNMLGQHRFEFTSRSDSLYRL 111 89****************9988522255669******99.99******************7777******************************** PP DBB 95 LksaadPvefmCqalkissvdkekLDklLteslkknipasgfqll 139 L a dP+ fmC al+is+ + ++LD+ L+ ++++ p + f+ l FUN_000896-T2 112 LYGALDPISFMCEALQISPPELHELDHSLAVTFQTKAPHG-FEFL 155 *************************************998.8876 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 2.7e-06 0.012 19 74 .. 162 220 .. 142 229 .. 0.74 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 2.7e-06 Ank_2 19 gadanlqdkngetaLhlAaknghleivklLle....hg.advndnngrtaLhyAaesghle 74 ga++ d++ t Lh+A+k+g ++++++Ll h+ +++++ +g+ + +A g e FUN_000896-T2 162 GAEK--SDSEHPTLLHFACKYGLTNLCQVLLTypgaHEaCSLKNYEGQRPYNLAQNLGFRE 220 3333..366889*******************966655534444799999999996556655 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 8.8e-06 0.037 18 56 .] 172 213 .. 161 213 .. 0.81 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 8.8e-06 Ank_5 18 tpLhvAakygaleivrlLl...angvdlnlkdeegltpldlA 56 t Lh+A+kyg ++ ++Ll ++++ lk+ eg+ p+ lA FUN_000896-T2 172 TLLHFACKYGLTNLCQVLLtypGAHEACSLKNYEGQRPYNLA 213 89*****************87777778888877777666665 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 2.7e-05 0.12 4 27 .. 172 195 .. 169 204 .. 0.90 2 ? -3.0 0.0 6 2.6e+04 14 23 .. 455 464 .. 453 467 .. 0.77 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 2.7e-05 Ank_3 4 tpLhlAarngrleivklLleklga 27 t+Lh+A+++g ++++Ll +ga FUN_000896-T2 172 TLLHFACKYGLTNLCQVLLTYPGA 195 9******************97766 PP == domain 2 score: -3.0 bits; conditional E-value: 6 Ank_3 14 rleivklLle 23 r ++++Ll+ FUN_000896-T2 455 RKNMLQMLLN 464 5679999998 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.2 0.00023 0.99 4 26 .. 172 195 .. 172 203 .. 0.86 2 ? -2.8 0.0 3.8 1.6e+04 14 23 .. 455 464 .. 451 465 .. 0.72 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00023 Ank 4 TPLHlAaraghlevvklLLkh.GA 26 T LH A+++g +++++ LL + GA FUN_000896-T2 172 TLLHFACKYGLTNLCQVLLTYpGA 195 89*****************44466 PP == domain 2 score: -2.8 bits; conditional E-value: 3.8 Ank 14 hlevvklLLk 23 + +++++LL+ FUN_000896-T2 455 RKNMLQMLLN 464 45599***94 PP >> DUF6788 Domain of unknown function (DUF6788) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.3 0.0015 6.5 11 58 .. 221 272 .. 217 282 .. 0.73 2 ? 2.4 0.1 0.053 2.2e+02 39 62 .. 290 313 .. 281 316 .. 0.76 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0015 DUF6788 11 leeklael...gslveeyrrcGkpnckcareg.hgpYwYlywregGktkskY 58 l++++ + gs + +r+ G+ + + ++ g Y+Y ++++g Y FUN_000896-T2 221 LADEIRKFqdsGSGYVSMRQEGNDGVYVRMQKpDGSYCYISKKQGDESSEWY 272 444444444457777888899999996444455***********99887777 PP == domain 2 score: 2.4 bits; conditional E-value: 0.053 DUF6788 39 ghgpYwYlywregGktkskYigkd 62 g Y+Y reg +k ++ig + FUN_000896-T2 290 DDGAYYYIAMREGVCVKPTHIGNK 313 38**********977777777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (540 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 959 (0.0375416); expected 510.9 (0.02) Passed bias filter: 744 (0.0291251); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.37u 0.42s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 5158.85 // Query: FUN_000897-T1 [L=786] Description: FUN_000897 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-07 31.6 0.0 4.9e-07 30.3 0.0 1.6 1 SEA SEA domain Domain annotation for each model (and alignments): >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.0 1.9e-11 4.9e-07 2 77 .. 527 594 .. 526 601 .. 0.93 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 1.9e-11 SEA 2 yytgsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspekgsvvvdvvlvfrfps 77 +++g +++++ y+ l++++S+efk+l++k+ ++++ + + +++v +++p gs++vd+ l+f ++ FUN_000897-T1 527 SFNGVLRLPSAAYKAPLNDKKSPEFKNLANKLCKMVKSAIKA------ITECNVQSFRP--GSLLVDFYLKFLSSV 594 79***************************************9......67*********..***********8874 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (786 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4269 (0.167117); expected 510.9 (0.02) Passed bias filter: 878 (0.0343707); expected 510.9 (0.02) Passed Vit filter: 538 (0.0210609); expected 25.5 (0.001) Passed Fwd filter: 150 (0.00587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 1.50u 0.46s 00:00:01.96 Elapsed: 00:00:00.49 # Mc/sec: 6423.54 // Query: FUN_000898-T1 [L=282] Description: FUN_000898 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-22 77.1 0.1 1.7e-21 76.4 0.1 1.4 1 GAS2 Growth-Arrest-Specific Protein 2 Domain 3.3e-10 40.6 0.1 7e-10 39.5 0.1 1.6 1 CH Calponin homology (CH) domain Domain annotation for each model (and alignments): >> GAS2 Growth-Arrest-Specific Protein 2 Domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.4 0.1 1.3e-25 1.7e-21 5 68 .. 193 255 .. 189 256 .. 0.90 Alignments for each domain: == domain 1 score: 76.4 bits; conditional E-value: 1.3e-25 GAS2 5 vrrivekctcpkkfkvekvsegkYrfgdsqklvlvRilrkhvmVRVGGGWdtLeeyLekhdpcr 68 ++ v++ + + +++e+++eg+Y + + + +++vRilr+hvmVRVGGGWdtLe++L++hdp + FUN_000898-T1 193 IDAEVARLSAKYGIRIERIKEGRYVVDG-KINIFVRILRNHVMVRVGGGWDTLEHFLSRHDPNK 255 666677778888899***********99.69*******************************86 PP >> CH Calponin homology (CH) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.5 0.1 5.5e-14 7e-10 3 106 .. 26 145 .. 24 148 .. 0.80 Alignments for each domain: == domain 1 score: 39.5 bits; conditional E-value: 5.5e-14 CH 3 eekellrWinsvlaeygekvkvenftedlrDGlaLckLlnkl.................apglvdkkklnks............efdkleNinlal 69 +++l +W+ +vl+e+ ++ +nf + l +G++ ckL++ + a f +++N+ +l FUN_000898-T1 26 LKEDLAEWLSRVLKEN---ITADNFMDRLENGVLVCKLAQIMqaaarnvpkngrsvkplA-----------PfafkfhqnakagTFFARDNAAHFL 107 799**********875...6668*******************555555555555555554...........055555555566************* PP CH 70 dvaekklgvpkvli.eaedlvegknk.svltllasLfra 106 ++++ +++v++ + e++ lv ++ +v+ +l+ +r+ FUN_000898-T1 108 QWCR-EIKVQDSVLfESDGLVLQRQPrEVILCLLDVARV 145 ****.******9999*******66666****99987776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (282 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 894 (0.0349971); expected 510.9 (0.02) Passed bias filter: 676 (0.0264631); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2723.60 // Query: FUN_000899-T1 [L=153] Description: FUN_000899 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-12 46.4 8.9 5.3e-12 46.2 8.9 1.1 1 SVIP Small VCP/p97-interacting protein Domain annotation for each model (and alignments): >> SVIP Small VCP/p97-interacting protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 8.9 2.1e-16 5.3e-12 1 62 [. 2 64 .. 2 68 .. 0.88 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 2.1e-16 SVIP 1 Grclscgggsseeeaetls...pReaaaeAAEkRqqesekrgikgalgkklaqeraksaekhlke 62 G+cl c++++ e e+ ++ +R+++ eAA kRqq+se+rg +++++ k++q+r++ +ek + FUN_000899-T1 2 GCCLDCLSPQPEVEN--PDpeiRRRQQEEAALKRQQQSEARGVRDPERLKREQKRKENREKEALK 64 89****888888775..5555**************************************998655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (153 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1631 (0.0638481); expected 510.9 (0.02) Passed bias filter: 791 (0.030965); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.42s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 1523.47 // Query: FUN_000900-T1 [L=516] Description: FUN_000900 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-34 117.1 0.0 1.3e-33 116.0 0.0 1.6 1 ArfGap Putative GTPase activating protein for Arf ------ inclusion threshold ------ 0.18 12.3 0.3 3.8 8.1 0.0 2.4 2 zf-dskA_traR Prokaryotic dksA/traR C4-type zinc finger Domain annotation for each model (and alignments): >> ArfGap Putative GTPase activating protein for Arf # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 116.0 0.0 1e-37 1.3e-33 3 113 .. 14 120 .. 12 124 .. 0.91 Alignments for each domain: == domain 1 score: 116.0 bits; conditional E-value: 1e-37 ArfGap 3 alkellkepenkvCaDCgaknptwaslnlgvfiCieCsgvHRslgvhiskvrsltldk.wteeelellkalgnkkaneifeaklpkeekkkkssdk 97 ++k+l++ penk+C+DCg++nptwas+++gvf+Ci+Cs+vHRslgvh++++rs++ld+ wt +l+ ++ +gn+kan++f ++ +++++ FUN_000900-T1 14 IFKRLRALPENKTCFDCGHSNPTWASVTYGVFLCIDCSAVHRSLGVHLTFIRSTQLDTnWTWLQLRAMQVGGNAKANAFFRQHNL-----STEDSG 104 6899*****************************************************99**********************9983.....345668 PP ArfGap 98 ekresfirakYeekkf 113 +k++s +++ Y+ek FUN_000900-T1 105 AKYRSRVAQMYREKLA 120 8888888888888865 PP >> zf-dskA_traR Prokaryotic dksA/traR C4-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.0003 3.8 16 32 .. 16 32 .. 15 34 .. 0.90 2 ? 1.6 0.1 0.031 3.9e+02 4 9 .. 43 50 .. 41 54 .. 0.60 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0003 zf-dskA_traR 16 aRlravPgarlCieCqe 32 Rlra+P + C +C + FUN_000900-T1 16 KRLRALPENKTCFDCGH 32 6**************75 PP == domain 2 score: 1.6 bits; conditional E-value: 0.031 zf-dskA_traR 4 gi..CedC 9 g+ C+dC FUN_000900-T1 43 GVflCIDC 50 55555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (516 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 989 (0.038716); expected 510.9 (0.02) Passed bias filter: 663 (0.0259542); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5071.77 // Query: FUN_000901-T1 [L=321] Description: FUN_000901 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-09 35.9 10.0 3.3e-09 35.9 10.0 2.1 2 SCP-1 Synaptonemal complex protein 1 (SCP-1) 2.6e-05 22.8 60.5 0.00015 20.3 37.4 2.0 2 CCDC39 Coiled-coil domain-containing protein 39 6.1e-05 23.8 27.8 6.1e-05 23.8 27.8 2.2 2 ATG16 Autophagy protein 16 (ATG16) 0.0031 16.8 46.9 0.0037 16.6 46.9 1.0 1 HOOK HOOK protein coiled-coil region 0.0096 16.5 6.2 0.0096 16.5 6.2 4.3 3 Nuf2_DHR10-like Nuf2, DHR10-like domain ------ inclusion threshold ------ 0.012 16.1 10.6 0.012 16.1 10.6 3.7 2 YscO Type III secretion protein YscO 0.031 14.8 2.2 0.031 14.8 2.2 5.1 5 CCDC138_cc Coiled-coil-domain-containing protein 138, c 0.034 14.7 60.7 2.8 8.4 16.6 3.4 4 UPF0242 Uncharacterised protein family (UPF0242) N-t 0.044 14.7 7.2 0.044 14.7 7.2 4.2 4 Snapin_Pallidin Snapin/Pallidin 0.068 14.2 0.6 0.068 14.2 0.6 3.7 3 DUF7310 Coiled-coil region of unknown function (DUF7 1.2 8.7 52.6 33 3.9 52.7 2.3 1 CCDC22_CC CCDC22 protein coiled-coil region 2.6 8.8 56.5 0.043 14.6 15.4 4.4 4 Rab11-FIP3 Rab11-FIP3-like domain 3.8 6.5 36.8 5.1 6.1 36.8 1.1 1 Macoilin Macoilin family 4.2 6.4 44.8 0.12 11.6 29.2 2.1 2 AAA_13 AAA domain 4.4 8.0 45.5 0.32 11.6 7.5 4.1 4 COG6_N Conserved oligomeric complex COG6, N-termina 4.8 7.7 19.3 2.2 8.8 3.9 3.2 3 Baculo_PEP_C Baculovirus polyhedron envelope protein, PEP Domain annotation for each model (and alignments): >> SCP-1 Synaptonemal complex protein 1 (SCP-1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 10.0 2.1e-12 3.3e-09 72 131 .. 84 143 .. 70 167 .. 0.83 2 ? -5.9 29.9 9 1.4e+04 489 635 .. 150 297 .. 139 318 .. 0.62 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 2.1e-12 SCP-1 72 nseglsrlysklykeaekikkwkvsieaelkqkesklqenrkiieaqrkaiqelqfenek 131 +e + l+++l++eaeki+kwk s+e e+k+ke+kl e + i++qrk+i +lq k FUN_000901-T1 84 SAERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEAVQTIDSQRKSILDLQELVVK 143 568899999******************************************999955444 PP == domain 2 score: -5.9 bits; conditional E-value: 9 SCP-1 489 eltansdklllenkklvqeasdmvlelkkqqediinnkkqeermlkqietleeketqlrdelesvrke...lkqkrdevkckldkseenarsieye 581 e t + +k+ + +e d++le ++ e +k q + + ++ ++ e ++ le+ r+e lk + ++ kldk e s++ + FUN_000901-T1 150 EHTDKYNKMKNKFDGQKREHEDFILESTEKLEK---AKSQIQVLQNERQAKESSISTMQAALEKSREEstsLKHQLASLQEKLDKLEGTITSMQAK 242 445555555544445555666666665444443...333333222222222233334556666666664445667777888999999999999999 PP SCP-1 582 vlkkekqlkilenkcnnlkkqvenkskyieelqqenkalkkkssa.eskqlnvye 635 + + e++l + +c+++ + + + ++ee qq+nk +k + +++q +v e FUN_000901-T1 243 LKNTEEKLSSSKGECKKIEEEFKVTQSQLEESQQDNKNIKVEMTKlKEQQKQVLE 297 9999999999999999999999999999999999999999876651333444443 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 32.6 0.00018 0.29 367 510 .. 72 214 .. 68 214 .. 0.91 2 ! 20.3 37.4 9.2e-08 0.00015 259 399 .. 164 304 .. 152 316 .. 0.91 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00018 CCDC39 367 eeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellyn.qefqiqqlerkvarlkgerseee 461 +e+ek++ke ++ ++++ + + +qe ++++ ++++e+e++ e+++++ + i+++ + +l qel+ + q++qi+ k +++k++ + + FUN_000901-T1 72 KENEKAEKERKQSAERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEAVQTIDSQRKSILDLQELVVKfQDLQIEH-TDKYNKMKNKFD-GQ 165 7899*****************************************************************98846777766.568999998754.56 PP CCDC39 462 keelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkee 510 k+e e+ i e +e+l++ k++ + Lq++ + e+ + ++ +lek++ee FUN_000901-T1 166 KREHEDFILESTEKLEKAKSQIQVLQNERQAKESSISTMQAALEKSREE 214 6677888**************************************9987 PP == domain 2 score: 20.3 bits; conditional E-value: 9.2e-08 CCDC39 259 ennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktls 354 + +e e i e ++kl k +++ + l++e + e+ + t++ l+++ ++ ++ + +++ l++++++ e ++ +++kl++++ekl++ k + + FUN_000901-T1 164 GQKREHEDFILESTEKLEKAKSQIQVLQNERQAKESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKLSSSKGECKK 259 57889999999************************************************************************************* PP CCDC39 355 aeerakeleklleeeekrlkeldkeikklkealfkksqelkelks 399 +ee k + lee ++ +k+++ e++klke++ ++ +el e s FUN_000901-T1 260 IEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQKQVLEELEEHIS 304 *******************************99998888877555 PP >> ATG16 Autophagy protein 16 (ATG16) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 12.0 0.016 26 54 132 .. 63 141 .. 5 147 .. 0.63 2 ! 23.8 27.8 3.8e-08 6.1e-05 17 173 .. 148 298 .. 143 308 .. 0.86 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.016 ATG16 54 qstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaer 132 +++++ +++ke+e+ +++++++ + +++ ++l +e ++ ++ ++ + + +e++++l+e +++ ++++++ +l++ + FUN_000901-T1 63 RPSTPRQKEKENEKAEKERKQSAERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEAVQTIDSQRKSILDLQELV 141 2222222333333333334455555555566666677777777777777777777777777777777777777777654 PP == domain 2 score: 23.8 bits; conditional E-value: 3.8e-08 ATG16 17 faelieaYnrLldrtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelq 112 + e + Yn++ ++++ ++e + e++++ ++++++ + ++e +a++ ++i++++++l + ree + + + + l+++l +l+ +++ FUN_000901-T1 148 QIEHTDKYNKMKNKFDGQKREHEDFILESTEKLEKAKSQIQVL--QNERQAKE----SSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTIT 237 5678899*****************9888877777544444433..44444444....5599*********************************** PP ATG16 113 elekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEek 173 ++kl++ e++l++ + e+++ ee+ k + +l+e ++ +++++ E++ L+ q +++ e+ FUN_000901-T1 238 SMQAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQKQVLEE 298 ***************************************************9998876555 PP >> HOOK HOOK protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 46.9 2.3e-06 0.0037 157 408 .. 69 317 .. 51 321 .] 0.83 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 2.3e-06 HOOK 157 eleeelkkanalrsqlelykrqvqelhkkldeeskkadklefelk.kleeklealqkekerliseRDtLrEtneELkCaqlqqaelsqadalakes 251 + e+e ka++ r q ++q lh++l +e++k k++ ++ +++ek + l + +++ s+R ++ + +e L ++ q+ +++++d+ +k + FUN_000901-T1 69 QKEKENEKAEKERKQ---SAERIQSLHTRLHQEAEKIRKWKTSTEiEMKEKEKKLHEAVQTIDSQRKSILDLQE-LV-VKFQDLQIEHTDKYNKMK 159 678888888888887...4578******************9876547889999999999999999999988665.43.455555555677555554 PP HOOK 252 s.esvdnlaaelvpaelrekllrLqrENKmLrlkqegseeeklaelqalLedanrrkneLetenrlanqrileLkaqvEelqkalqeqgskaedss 346 + +++ ++e +e ekl++ ++ +L+ + +++ e + ++qa Le ++++ +L+++ + ++++ +L+ + +q +l++++ k +s FUN_000901-T1 160 NkFDGQKREHEDFILESTEKLEKAKSQIQVLQNERQAK-ESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKLSSSK 254 423567788888999****************6665555.999****************************************************99 PP HOOK 347 llkkkleehleklkeaqeelqkkkelleelepkldssl.kkieeLqeaLkkkdedmkameerY 408 kk+ee+++ ++ ee q+ ++ + +kl++++ + +eeL+e+++ + meer+ FUN_000901-T1 255 GECKKIEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQkQVLEELEEHISSLLTSKQTMEERF 317 9********9999988888888888887666666665548899********9999999**997 PP >> Nuf2_DHR10-like Nuf2, DHR10-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 15.7 0.95 1.5e+03 63 115 .. 71 123 .. 67 125 .. 0.93 2 ! 16.5 6.2 6e-06 0.0096 45 96 .. 201 252 .. 198 258 .. 0.95 3 ? 2.7 12.7 0.11 1.7e+02 29 85 .. 258 315 .. 256 318 .. 0.85 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.95 Nuf2_DHR10-like 63 rdaleekeielrelerkeerlqrqlenaqeklerlreqaeekreaakarleel 115 +++ e++e+e+++ +++ l+ +l + ek+ + + e ++++ +++l+e+ FUN_000901-T1 71 EKENEKAEKERKQSAERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEA 123 5678999*******************************************997 PP == domain 2 score: 16.5 bits; conditional E-value: 6e-06 Nuf2_DHR10-like 45 iekelakleeakkklkelrdaleekeielrelerkeerlqrqlenaqekler 96 i++ +a+le+++++ ++l+ +l++ +++l +le +++ +q +l+n++ekl++ FUN_000901-T1 201 ISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKLSS 252 78999********************************************986 PP == domain 3 score: 2.7 bits; conditional E-value: 0.11 Nuf2_DHR10-like 29 qvvekdlrsciklleeiekelakleeakkklkelrda.leekeielrelerkeerlqr 85 +++e++ + ++ +lee +++ + + ++ klke++++ lee e+ + l + ++ ++ FUN_000901-T1 258 KKIEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQKQvLEELEEHISSLLTSKQTMEE 315 589*****************************99887367778888888888887776 PP >> YscO Type III secretion protein YscO # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.1 10.6 7.7e-06 0.012 65 136 .. 177 248 .. 173 250 .. 0.94 2 ? 0.4 14.1 0.55 8.8e+02 65 140 .. 226 301 .. 225 317 .. 0.93 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 7.7e-06 YscO 65 lkelekvqqqvgsLrekeaslekqleeaeqqleaerealrqarkqlqearravekfaelvrlvqaeelaqae 136 +++lek+++q+ L ++ + +e+ + ++++le+ re++++++ ql+ ++ ++ k++ + +qa ++ e FUN_000901-T1 177 TEKLEKAKSQIQVLQNERQAKESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEE 248 689*****************************************************9999999999888766 PP == domain 2 score: 0.4 bits; conditional E-value: 0.55 YscO 65 lkelekvqqqvgsLrekeaslekqleeaeqqleaerealrqarkqlqearravekfaelvrlvqaeelaqaerkEe 140 +++l+k+ ++s+ +k ++ e++l + + ++ +e+ + + ql+e ++ + ++ ++ ++++++++ e++Ee FUN_000901-T1 226 QEKLDKLEGTITSMQAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQKQVLEELEE 301 6789***********************************************9999999999999888888888887 PP >> CCDC138_cc Coiled-coil-domain-containing protein 138, coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 1.6 1.6 2.6e+03 29 50 .. 72 93 .. 68 104 .. 0.65 2 ? -0.4 0.4 1.1 1.7e+03 13 30 .. 113 130 .. 102 143 .. 0.57 3 ? -1.3 4.1 2.1 3.3e+03 10 43 .. 155 189 .. 152 205 .. 0.75 4 ? 14.8 2.2 1.9e-05 0.031 14 52 .. 212 250 .. 203 259 .. 0.87 5 ? -1.4 7.0 2.2 3.5e+03 11 41 .. 272 295 .. 256 315 .. 0.66 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.6 CCDC138_cc 29 eqnkkLesQskkvqaRLeNLqR 50 ++n+k e+ k+ +R++ L FUN_000901-T1 72 KENEKAEKERKQSAERIQSLHT 93 6677777777777777776653 PP == domain 2 score: -0.4 bits; conditional E-value: 1.1 CCDC138_cc 13 lkelNDslkkqlnevseq 30 +ke +l ++++ +q FUN_000901-T1 113 MKEKEKKLHEAVQTIDSQ 130 333333333333333333 PP == domain 3 score: -1.3 bits; conditional E-value: 2.1 CCDC138_cc 10 FdtlkelNDslkkqlne.vseqnkkLesQskkvqa 43 ++ +k+ D k++ ++ + e+ +kLe+ ++++q FUN_000901-T1 155 YNKMKNKFDGQKREHEDfILESTEKLEKAKSQIQV 189 56788888888888877467999999999999885 PP == domain 4 score: 14.8 bits; conditional E-value: 1.9e-05 CCDC138_cc 14 kelNDslkkqlnevseqnkkLesQskkvqaRLeNLqRKq 52 +e slk ql +++e+ +kLe ++qa+L+N K FUN_000901-T1 212 REESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKL 250 566679****************************88775 PP == domain 5 score: -1.4 bits; conditional E-value: 2.2 CCDC138_cc 11 dtlkelNDslkkqlnevseqnkkLesQskkv 41 + ++ N ++k ++++++eq+k+ v FUN_000901-T1 272 EESQQDNKNIKVEMTKLKEQQKQ-------V 295 44456677777777777776665.......3 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 16.6 0.0018 2.8 101 173 .. 69 141 .. 63 150 .. 0.84 2 ? 6.4 9.4 0.0074 12 114 172 .. 149 207 .. 136 211 .. 0.82 3 ? 7.1 11.9 0.0044 7.1 60 136 .. 157 231 .. 153 234 .. 0.82 4 ? 6.3 25.8 0.0076 12 73 162 .. 218 306 .. 193 317 .. 0.67 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0018 UPF0242 101 eleeelsqkeeeleklkeekeqlklkleqisqdfaefkleseeqlkekqlllneyqetieeqrsvlekrqdqi 173 + e+e ++ e+e ++ e+ ++l+++l+q + + ++k e ++kek++ l+e +ti +qr+++ + q+ + FUN_000901-T1 69 QKEKENEKAEKERKQSAERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEAVQTIDSQRKSILDLQELV 141 456666777778888889999*******************************************998887754 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0074 UPF0242 114 eklkeekeqlklkleqisqdfaefkleseeqlkekqlllneyqetieeqrsvlekrqdq 172 +++++ +++k k + +++ ++f les e+l++ + +++ +q++ + + s++ q+ FUN_000901-T1 149 IEHTDKYNKMKNKFDGQKREHEDFILESTEKLEKAKSQIQVLQNERQAKESSISTMQAA 207 4567777788999999999**************************99999999888876 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0044 UPF0242 60 alkekfeksfleekeallteedaedlkileeeleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfae 136 +k+kf+ ++ e e ++ e e+l++ + +++ lq+e + e +s ++ +lek +ee +lk +l ++ ++ FUN_000901-T1 157 KMKNKFDGQKR-EHEDFILEST-EKLEKAKSQIQVLQNERQAKESSISTMQAALEKSREESTSLKHQLASLQEKLDK 231 56677766554.4566666666.79999999*************************************999987765 PP == domain 4 score: 6.3 bits; conditional E-value: 0.0076 UPF0242 73 keallteedaedlkileeeleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfaefkleseeqlkekqlllneyqetieeq 162 ++ l++++ e+l +le ++ +q++ ++ ee+ls+ + e +k +ee + +++le+ +qd+++ k e+ +++++ l+e++e+i+++ FUN_000901-T1 218 LKHQLASLQ-EKLDKLEGTITSMQAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQKQVLEELEEHISSL 306 223334444.67777778888888888888888888888888888888888888888888888888888877777777788888888765 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 4.6 0.1 1.6e+02 30 83 .. 89 139 .. 76 146 .. 0.79 2 ? 0.9 3.3 0.57 9.1e+02 29 77 .. 148 193 .. 133 198 .. 0.71 3 ? 14.7 7.2 2.8e-05 0.044 12 86 .. 198 272 .. 194 275 .. 0.92 4 ? 1.2 6.1 0.44 7e+02 37 72 .. 279 314 .. 263 316 .. 0.60 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.1 Snapin_Pallidin 30 eeLleqidrlaeeLqeleelqeevlpdlkeyakKLvnikkrmsslnerlqklqk 83 + L+++++++ae++++ + +e +++ke+ kKL+++ + + s + + lq+ FUN_000901-T1 89 QSLHTRLHQEAEKIRKWKTSTE---IEMKEKEKKLHEAVQTIDSQRKSILDLQE 139 46999*****************...88888888888877777766666655554 PP == domain 2 score: 0.9 bits; conditional E-value: 0.57 Snapin_Pallidin 29 QeeLleqidrlaeeLqeleelqeevlpdlkeyakKLvnikkrmsslner 77 Q e ++ ++++++++ ++++e ++ e +KL ++k +++ l++ FUN_000901-T1 148 QIEHTDKYNKMKNKFDGQKREHE---DFILESTEKLEKAKSQIQVLQNE 193 44445555566666666666666...999999************99986 PP == domain 3 score: 14.7 bits; conditional E-value: 2.8e-05 Snapin_Pallidin 12 epklkeldeklkelrqsQeeLleqidrlaeeLqeleelqeevlpdlkeyakKLvnikkrmsslnerlqklqkRae 86 e+++ +++ l++ r++ + L++q+ +l+e+L++le + ++ ++lk+ +KL++ k + ++++e + +q +e FUN_000901-T1 198 ESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLE 272 5789999***************************9988888************************9999887765 PP == domain 4 score: 1.2 bits; conditional E-value: 0.44 Snapin_Pallidin 37 drlaeeLqeleelqeevlpdlkeyakKLvnikkrms 72 ++ + e+++l+e q++vl++l+e++ L + k+ m+ FUN_000901-T1 279 KNIKVEMTKLKEQQKQVLEELEEHISSLLTSKQTME 314 233445555556666678888888888888888775 PP >> DUF7310 Coiled-coil region of unknown function (DUF7310) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.7 0.13 2e+02 24 47 .. 73 96 .. 65 110 .. 0.68 2 ? 14.2 0.6 4.2e-05 0.068 22 63 .. 204 246 .. 175 253 .. 0.74 3 ? 1.1 0.3 0.52 8.3e+02 31 49 .. 288 306 .. 263 316 .. 0.50 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.13 DUF7310 24 daaalaerlealeerldeleerla 47 +++++++++++ +er+++l +rl FUN_000901-T1 73 ENEKAEKERKQSAERIQSLHTRLH 96 445556666667777777777764 PP == domain 2 score: 14.2 bits; conditional E-value: 4.2e-05 DUF7310 22 la.daaalaerlealeerldeleerlaeLeaavqAlrGyvGsv 63 ++ ++ +e+ ++l+ +l++l+e+l++Le+++ +++ + + FUN_000901-T1 204 MQaALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNT 246 3323444566777799999999999999999999988777665 PP == domain 3 score: 1.1 bits; conditional E-value: 0.52 DUF7310 31 rlealeerldeleerlaeL 49 e+ ++ l+elee++++L FUN_000901-T1 288 LKEQQKQVLEELEEHISSL 306 2222333344444444444 PP >> CCDC22_CC CCDC22 protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 52.7 0.021 33 62 298 .. 45 301 .. 7 317 .. 0.60 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.021 CCDC22_CC 62 fyse.llppvtaqlssrasvvaSlleknaael.aaaqeweeewneqgl.ssr.lteeeyrkrkkkkllkriaeq..lrsaalkseeaesgasksks 151 + ++ +++pv+ +s++++ +S+ ++ +e a++e+ ++++ + ++r ++e+e ++ k++++ +++e+ ++a+++ +++ks FUN_000901-T1 45 HGNQlNIRPVN--SPSSSYFRPSTPRQKEKENeKAEKERKQSAERIQSlHTRlHQEAEKIRKWKTSTEIEMKEKekKLHEAVQTI---DSQRKSIL 135 44555777777..788899999999966655413445555555543335888544444444444444444444400444444444...35578889 PP CCDC22_CC 152 dlsellssf............seksetdsslakgsrf..thaeklqftqeaaa.........aassaakkaeteeelkkqreeeleeLqeqleele 224 dl+el+ +f ++k++ d ++ + + f +++ekl +++ + ++++ + ++ + l+k re e ++L+ ql +l+ FUN_000901-T1 136 DLQELVVKFqdlqiehtdkynKMKNKFDGQKREHEDFilESTEKL--EKA--KsqiqvlqneRQAKESSISTMQAALEKSRE-ESTSLKHQLASLQ 226 999999999776665555555333333333333332211233333..111..022333333222223333444444555555.5588999999999 PP CCDC22_CC 225 ssieeleeelkklessikqveeeleekeeeneelekevkvkkktldLLpdaeenia.kLqklveasaqrlveLae 298 ++ ++le+ + ++++++k +ee+l + e+++ e+e kv + l+ +++++ni+ + kl e+ +q l eL+e FUN_000901-T1 227 EKLDKLEGTITSMQAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLEESQQDNKNIKvEMTKLKEQQKQVLEELEE 301 999999999999999999999999999999999999999988888888888888864555555555555555554 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 8.5 0.0055 8.7 73 121 .. 62 111 .. 57 116 .. 0.86 2 ? -0.6 16.7 1.3 2.1e+03 23 111 .. 113 214 .. 106 216 .. 0.64 3 ? 14.6 15.4 2.7e-05 0.043 38 120 .. 182 265 .. 171 270 .. 0.81 4 ? 1.2 10.2 0.37 5.9e+02 56 106 .. 264 314 .. 261 317 .. 0.78 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0055 Rab11-FIP3 73 Lrsevprlk.aqlerleeekqklqdeleelslelkeereeerkledklsq 121 +r ++pr+k ++ e++e+e+++ +++++l+++l++e e+ rk++ + + FUN_000901-T1 62 FRPSTPRQKeKENEKAEKERKQSAERIQSLHTRLHQEAEKIRKWKTSTEI 111 5677888885789*******************************987665 PP == domain 2 score: -0.6 bits; conditional E-value: 1.3 Rab11-FIP3 23 lkeqelraeerleeeqrrhrealsrle.........RekelelenlqaRlqqleeEnseL....rsevprlkaqlerleeekqklqdeleelslel 105 +ke+e + e +++ ++++++l +e e++ + ++++++ ++E++++ ++++++ k+q++ l++e+q ++ +++++ l FUN_000901-T1 113 MKEKEKKLHEAVQTIDSQRKSILDLQElvvkfqdlqIEHTDKYNKMKNKFDGQKREHEDFilesTEKLEKAKSQIQVLQNERQAKESSISTMQAAL 208 566666666666665555554443322222000111455556666777777777777776555567788999999999999999999999999999 PP Rab11-FIP3 106 keeree 111 ++ ree FUN_000901-T1 209 EKSREE 214 999987 PP == domain 3 score: 14.6 bits; conditional E-value: 2.7e-05 Rab11-FIP3 38 qrrhrealsrleRe.kelelenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelkeereeerkledkls 120 + +++ ++ + eR+ ke ++++qa l++ +eE+++L+ ++ l+++l++le +++q +l++++++l++ + e +k+e++++ FUN_000901-T1 182 KAKSQIQVLQNERQaKESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKLSSSKGECKKIEEEFK 265 33333334444554256789***********************************************************99876 PP == domain 4 score: 1.2 bits; conditional E-value: 0.37 Rab11-FIP3 56 lenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelk 106 + q++l++ +++n++++ e+++lk+q +++ ee ++ + l + +++++ FUN_000901-T1 264 FKVTQSQLEESQQDNKNIKVEMTKLKEQQKQVLEELEEHISSLLTSKQTME 314 56678999999***************9998888888777776666655554 PP >> Macoilin Macoilin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 36.8 0.0032 5.1 231 480 .. 74 314 .. 51 318 .. 0.52 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0032 Macoilin 231 kngaarskkdstlklpeleyrekkkskkesekeskkskni.lqsvdsklqeleymenkinakrlseeelesseedllkeesakskkssasseskny 325 +++a++++k+s++++ l++r +++ +k + k s++i +++ ++kl+e+ + + + l+ +el ++ +dl+ e+ k +k ++++ FUN_000901-T1 74 NEKAEKERKQSAERIQSLHTRLHQEAEKIR--KWKTSTEIeMKEKEKKLHEAVQTIDSQRKSILDLQELVVKFQDLQIEHTDKYNK-----MKNKF 162 222233333455555555555543332222..222222221223333333333333333333334444444444444433333332.....22333 PP Macoilin 326 kkasskaanssnssprslksssgsvsssssskndkkqklpagkasaaskdkvenllpnnqlskpdalvrleqdikklkadlqasrqveqelrsqis 421 + ++ + + s+++l++++++++ +++++ k ++++ +a+ + + +l + +s +++l +le +i ++a+l+++ ++ + + + + FUN_000901-T1 163 DGQKREHEDFILESTEKLEKAKSQIQVLQNERQAKESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKNTEEKLSSSKGECK 258 444444556667777777777777777766666555555433322233333445566666777777777777777777777777777777777777 PP Macoilin 422 sltseerslkselgqlrqenellqtklhnlvsakqkdkqtvsqlekrlkaeqearaave 480 + +e + +s+l++ +q+n+ ++ + + k ++kq +++le ++ + ++ ++e FUN_000901-T1 259 KIEEEFKVTQSQLEESQQDNKNIKVEM---TKLKEQQKQVLEELEEHISSLLTSKQTME 314 777777777777777777777666544...44567777777777777776666666655 PP >> AAA_13 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 29.2 7.3e-05 0.12 312 469 .. 79 245 .. 65 251 .. 0.81 2 ? 5.9 12.4 0.0037 5.9 95 180 .. 226 306 .. 225 317 .. 0.69 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.3e-05 AAA_13 312 lasensafeld..keeleseaevleeqldglqqaleeKrkepfksie.lesvkakiesikdsvakinel....IakhNeivdnleeekekakkklr 400 +++++sa + + + l++eae+++++ + + +++eK k++ + ++ ++s + i ++++v k+++l k+N++ ++++ +k + ++ + FUN_000901-T1 79 KERKQSAERIQslHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEAVQtIDSQRKSILDLQELVVKFQDLqiehTDKYNKMKNKFDGQKREHEDFIL 174 33333433333448888999999999999999999*****9999888346666666888888888876431125699**********999999876 PP AAA_13 401 lhl..vaeikseideykkkykalekeinslekeikeeeeelkkleeeikeLekelkdekpaveeinklLka 469 + ++++ks+i+ ++++ +a e +i+ +++++++ ee l+ + + L+++l + + +++ ++++Lk+ FUN_000901-T1 175 ESTekLEKAKSQIQVLQNERQAKESSISTMQAALEKSREESTSLKHQLASLQEKLDKLEGTITSMQAKLKN 245 665468**************************************************************997 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0037 AAA_13 95 qekieklkkeikkaeeklkaaeanlqkaekekeklkkefleecakkl.kkkkaealsealkslkyeakfkkrllkeiekanrkaael 180 qek++kl++ i ++++klk++e++l++ ++e +k ++ef+ + ++ ++ +++++ + ++lk+ ++k++l+e+e+++ ++l FUN_000901-T1 226 QEKLDKLEGTITSMQAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLEeSQQDNKNIKVEMTKLKE---QQKQVLEELEEHI---SSL 306 899**********************************9996666533033444444444444444...5567777777763...444 PP >> COG6_N Conserved oligomeric complex COG6, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 9.6 0.89 1.4e+03 26 99 .. 72 146 .. 61 151 .. 0.83 2 ? 4.4 0.9 0.034 55 55 89 .. 154 189 .. 151 196 .. 0.83 3 ? 11.6 7.5 0.0002 0.32 33 88 .. 178 233 .. 167 237 .. 0.93 4 ? 8.8 10.8 0.0015 2.4 32 88 .. 240 296 .. 234 316 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.89 COG6_N 26 kineeflkefgpvaeqLkrieedveklnesceemkkkleaakeet.selleeassLkeekekielkqkllkafle 99 k+ne+ ke ++ ae+++++++ + + e + + k++ e +e ++l e ++++ +++++i q+l+ +f++ FUN_000901-T1 72 KENEKAEKERKQSAERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKeKKLHEAVQTIDSQRKSILDLQELVVKFQD 146 678888888899999999999999999999999998888765555488888899999999999999999999975 PP == domain 2 score: 4.4 bits; conditional E-value: 0.034 COG6_N 55 sceemkkkleaakeet.selleeassLkeekekiel 89 +++mk+k + +k+e + +le +++L++ k +i+ FUN_000901-T1 154 KYNKMKNKFDGQKREHeDFILESTEKLEKAKSQIQV 189 6799******99999945568999999999999986 PP == domain 3 score: 11.6 bits; conditional E-value: 0.0002 COG6_N 33 kefgpvaeqLkrieedveklnesceemkkkleaakeetselleeassLkeekekie 88 ++++++++q++ ++++ ++ ++s+++m+ +le+++ee+++l ++ +sL+e+++k+e FUN_000901-T1 178 EKLEKAKSQIQVLQNERQAKESSISTMQAALEKSREESTSLKHQLASLQEKLDKLE 233 678999**********************************************9997 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0015 COG6_N 32 lkefgpvaeqLkrieedveklnesceemkkkleaakeetselleeassLkeekekie 88 ++++++ e+L++ + +++k++e ++ ++++le+++++++++ e+++Lke+++++ FUN_000901-T1 240 QAKLKNTEEKLSSSKGECKKIEEEFKVTQSQLEESQQDNKNIKVEMTKLKEQQKQVL 296 56788999********************************************99985 PP >> Baculo_PEP_C Baculovirus polyhedron envelope protein, PEP, C terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.4 0.067 1.1e+02 38 82 .. 86 130 .. 81 163 .. 0.81 2 ? 8.8 3.9 0.0014 2.2 31 93 .. 186 249 .. 171 257 .. 0.47 3 ? 5.5 1.5 0.015 23 23 63 .. 272 312 .. 253 321 .] 0.75 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.067 Baculo_PEP_C 38 tlldaietqLndlsedlesllaeldtrldtlltnLtdalnqlqdt 82 + +++++t+L++ +e++++ ++ + ++++ ++L++a++++ + FUN_000901-T1 86 ERIQSLHTRLHQEAEKIRKWKTSTEIEMKEKEKKLHEAVQTIDSQ 130 556778888998899999988888889999999999999998743 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0014 Baculo_PEP_C 31 qilaqlttlldaietqLndlsedlesllaeldtrldtlltnLtdalnqlq...dtlrneLtnlnsi 93 qi l++ +a e+++++++++le+ + e +t l+++l+ L+++l +l+ ++++ +L+n++ + FUN_000901-T1 186 QI-QVLQNERQAKESSISTMQAALEK-SREESTSLKHQLASLQEKLDKLEgtiTSMQAKLKNTEEK 249 33.33444444445555555555555.333444444444444444444443333444444444444 PP == domain 3 score: 5.5 bits; conditional E-value: 0.015 Baculo_PEP_C 23 nairlqnvqilaqlttlldaietqLndlsedlesllaeldt 63 + + n +i ++t+l+++ +++L++l+e+++sll++ +t FUN_000901-T1 272 EESQQDNKNIKVEMTKLKEQQKQVLEELEEHISSLLTSKQT 312 44456677788888888888888888888888888876555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5976 (0.23394); expected 510.9 (0.02) Passed bias filter: 934 (0.0365629); expected 510.9 (0.02) Passed Vit filter: 333 (0.0130358); expected 25.5 (0.001) Passed Fwd filter: 160 (0.00626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.96u 0.44s 00:00:01.40 Elapsed: 00:00:00.45 # Mc/sec: 2867.63 // Query: FUN_000902-T1 [L=184] Description: FUN_000902 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00029 19.7 31.8 0.00041 19.2 31.8 1.1 1 FPP Filament-like plant protein, long coiled-c 0.00039 20.6 38.6 0.014 15.5 25.1 2.1 2 FKBP15 FK506-binding protein 15-like domain 0.0051 17.0 19.6 0.0051 17.0 19.6 2.8 2 KIF21A_4th KIF21A-like domain ------ inclusion threshold ------ 0.015 15.8 18.7 0.3 11.6 5.7 2.6 2 DUF1664 Protein of unknown function (DUF1664) 0.018 15.5 1.6 0.029 14.8 0.2 2.1 2 DUF1932 Domain of unknown function (DUF1932) 0.028 15.1 4.3 0.028 15.1 4.3 3.2 4 DUF3896 Protein of unknown function (DUF3896) 0.067 11.5 36.1 0.11 10.8 36.1 1.3 1 CCDC39 Coiled-coil domain-containing protein 39 0.067 13.7 0.2 0.067 13.7 0.2 2.3 2 Pam3_gp32 Phage Pam3 gp32-like protein 0.079 12.5 28.4 0.78 9.2 2.6 2.0 2 Rod_CreS Crescentin, rod domain 0.079 14.2 25.5 1.6 10.0 8.4 3.1 3 Occludin_ELL Occludin homology domain 0.2 11.5 31.4 0.15 11.9 28.8 1.9 1 LIP-1 Liprin-alpha-like coiled coil domain 2 0.35 11.4 39.5 0.12 12.9 31.3 2.7 2 CENP-F_leu_zip Leucine-rich repeats of kinetochore protei 0.39 11.3 41.5 0.057 14.0 12.3 3.0 2 ERM_helical Ezrin/radixin/moesin, alpha-helical domain 0.66 9.1 36.6 2.6 7.2 11.4 2.1 2 HOOK HOOK protein coiled-coil region 1.1 9.6 21.8 0.06 13.7 5.7 2.9 2 Nsp1_C Nsp1-like C-terminal region 1.1 10.2 27.6 2.9 8.8 27.4 1.7 1 Fez1 Fez1 1.2 10.0 29.2 4.1 8.2 8.6 3.2 3 CC_Bre1 Bre1, coiled-coil containing domain 1.3 9.1 30.6 3.2 7.9 9.3 2.4 2 CCDC113_CCDC96_CC CCDC113/CCDC96, coiled-coil 1.4 10.1 20.5 1.1 10.4 3.4 3.4 3 FliD_N Flagellar hook-associated protein 2 N-term 1.8 8.4 38.8 0.41 10.5 15.8 2.9 2 GAS Growth-arrest specific micro-tubule bindin 2.4 7.4 33.9 2.8 7.2 33.9 1.0 1 CALCOCO1 Calcium binding and coiled-coil domain (CA 2.6 7.9 7.6 3.4 7.5 1.6 2.1 2 NAD_binding_5 Myo-inositol-1-phosphate synthase 3.4 8.1 23.2 2.2 8.7 1.6 2.9 2 COG3_N Conserved oligomeric Golgi complex subunit 3.7 8.6 15.0 39 5.3 1.7 3.5 2 NPV_P10 Nucleopolyhedrovirus P10 protein 4.3 8.0 23.8 1.6 9.4 8.7 3.3 4 Fib_alpha Fibrinogen alpha/beta chain family 4.6 8.0 37.0 5.1 7.9 9.7 3.1 3 Rab11-FIP3 Rab11-FIP3-like domain 5 7.3 31.3 3.9 7.6 10.6 2.1 2 Mis12 Mis12 protein 5.9 7.6 36.9 2.9 8.6 13.8 2.5 2 OmpH Outer membrane protein (OmpH-like) 6.1 7.4 34.6 0.53 10.8 6.0 3.7 4 PUMA_CC PUMA coiled-coil 6.4 6.4 25.9 0.44 10.2 7.6 2.2 2 TMEM120A-B TMEM120A/B 6.5 7.0 17.2 2.1 8.6 4.1 2.6 2 Bacillus_HBL Bacillus haemolytic enterotoxin (HBL) 6.6 7.4 35.5 5.7 7.6 9.5 3.2 3 Sec2p GDP/GTP exchange factor Sec2p 7.1 7.2 35.8 2.3 8.8 18.6 2.2 2 ATG16 Autophagy protein 16 (ATG16) 7.3 4.6 9.3 11 4.0 9.3 1.4 1 ACR_tran AcrB/AcrD/AcrF family 7.7 6.9 35.9 6.5 7.1 16.3 3.0 3 DUF4515 Domain of unknown function (DUF4515) 7.8 6.2 29.4 5 6.8 9.0 3.0 3 DUF3450 Protein of unknown function (DUF3450) 8.4 7.0 28.2 5.6 7.6 7.8 3.7 3 Med9 RNA polymerase II transcription mediator c 8.8 7.4 9.1 8.1 7.5 0.4 3.5 5 HEF_HK HEF_HK domain Domain annotation for each model (and alignments): >> FPP Filament-like plant protein, long coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 31.8 6.1e-07 0.00041 679 848 .. 11 178 .. 2 180 .. 0.86 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 6.1e-07 FPP 679 elplvsgsdeskkeenkllkeeleelksekenlevelakatenlestkvqlqesEqllaelkseLeslkesnslaetqlkcmaesyesletraeel 774 +l ++ +s + +ke+ +l++ + ek++le+ + + +l + + + + +E+l+ +lk++L++ +++ns + +l++ +e++e ++ l FUN_000902-T1 11 DLQVKLESVKREKEKVDSLNDHI---MKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLL 103 44444444555555555555555...457777888888888889999999999******************************************* PP FPP 775 eaelnelkekieaLeveLeeekksheealakckelqeqlervekkels.kssaeeedkklkqekeiaaAaeKLae 848 + ++e ++ i+ Le + + + + + ++ k ++lq +le +k++ +ss e+ ++ +k+eke A +KL+e FUN_000902-T1 104 TLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQiQSSLEDFKNVSKSEKESQEAIQKLQE 178 ***************************************99877665559***********************98 PP >> FKBP15 FK506-binding protein 15-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 17.8 4.2e-05 0.028 109 202 .. 7 102 .. 2 110 .. 0.89 2 ! 15.5 25.1 2.1e-05 0.014 94 204 .. 62 172 .. 58 184 .] 0.88 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 4.2e-05 FKBP15 109 kkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsd..rkkkaaeerkrl 202 +k ++lq kl+s+++e+ek ++ +++ ++++ele+ + el+++l +e ++ + ee +++l+e+la ++ + l + l + r+ e++ rl FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEadRRNEEMEDKTRL 102 57799*************************************************************************998733565566667665 PP == domain 2 score: 15.5 bits; conditional E-value: 2.1e-05 FKBP15 94 taqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesleksls 189 ++ + +l+++la+ q ++ l+ +l++a +++e+ +++ l ee+++++++l+ ++ + ++k leekl+ l+ +l++ +++ke+++ sl+ FUN_000902-T1 62 EELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLE 157 556889****************************************************************************************** PP FKBP15 190 drkkkaaeerkrlee 204 d k +++e++ e+ FUN_000902-T1 158 DFKNVSKSEKESQEA 172 *99988888765443 PP >> KIF21A_4th KIF21A-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 13.7 0.95 6.4e+02 57 163 .. 3 73 .. 1 80 [. 0.37 2 ! 17.0 19.6 7.5e-06 0.0051 15 111 .. 85 181 .. 76 184 .] 0.81 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.95 KIF21A_4th 57 qqyekklkeLeeeikdlqkErdellqqlqniesksdekakklkeeyekklkelekeikeLkkkqkeqakllkqkeksekklkkLqsEiq.emKkq. 150 + +k+++L+ +++++++E++++ + +++k+k++ e + +Lq+ + em ++ FUN_000902-T1 3 EAAGEKIQDLQVKLESVKREKEKVDSLND---------------------------------------HIMKEKQELETAYGELQTSLSkEMERTs 59 33344444444444444444444432222.......................................2344444444444444444421333211 PP KIF21A_4th 151 .kvqLqkkmkeese 163 k +L++++ke FUN_000902-T1 60 sKEELVRQLKEKLA 73 14444444444444 PP == domain 2 score: 17.0 bits; conditional E-value: 7.5e-06 KIF21A_4th 15 keeehalrqeqlqkeLaeLnkeieiKeklikeleqsdt..etlkqqyekklkeLeeeikdlqkErdellqqlqniesksdekakklkeeyekklke 108 + +e ++r+e+++ + + L+ ie+K++ i+ le++ + k+ e+kl++L+ ++++ +k +++++++l++ ++ k++k ++e +kl+e FUN_000902-T1 85 DLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYnaSFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKN--VSKSEKESQEAIQKLQE 178 5578999**************************66655559999999**************************7777..35555555555566655 PP KIF21A_4th 109 lek 111 ++ FUN_000902-T1 179 ENR 181 444 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 5.7 0.00045 0.3 47 123 .. 23 99 .. 12 100 .. 0.90 2 ? 9.9 4.6 0.0016 1 56 108 .. 123 175 .. 106 182 .. 0.75 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00045 DUF1664 47 skqleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklkeieek 123 ++++++ +++ + K+eL+ +++++l + +e +++ +e v +++e+++++++ + + + + + + + +e+e+k FUN_000902-T1 23 KEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDK 99 56899999***********************************************9999999988888888888876 PP == domain 2 score: 9.9 bits; conditional E-value: 0.0016 DUF1664 56 slaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvke 108 + + tKk L+++++ +++kl+e + +++i++ + + ++ ++ ke +++++ FUN_000902-T1 123 NASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQK 175 45679*************************99987766554444444444443 PP >> DUF1932 Domain of unknown function (DUF1932) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.2 4.3e-05 0.029 8 45 .. 62 98 .. 56 104 .. 0.92 2 ? -2.2 0.1 8.5 5.7e+03 8 17 .. 136 145 .. 129 158 .. 0.59 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 4.3e-05 DUF1932 8 dellaeleeslpaflakaerlvprmapkAyRwveEMee 45 +el ++l+e l +f++ +++++r + A R+ eEMe FUN_000902-T1 62 EELVRQLKEKLAQFQDA-NSFLTRDLDEADRRNEEMED 98 7999*********9999.******************96 PP == domain 2 score: -2.2 bits; conditional E-value: 8.5 DUF1932 8 dellaelees 17 ++l+a lee+ FUN_000902-T1 136 QDLQAKLEEE 145 4555555553 PP >> DUF3896 Protein of unknown function (DUF3896) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.5 2 1.3e+03 16 36 .. 7 24 .. 2 36 .. 0.71 2 ? -1.0 0.2 4.2 2.8e+03 16 34 .. 35 54 .. 27 75 .. 0.55 3 ? 15.1 4.3 4.1e-05 0.028 5 45 .. 122 159 .. 119 164 .. 0.82 4 ? -1.1 1.9 4.6 3.1e+03 33 45 .. 147 159 .. 139 182 .. 0.54 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 2 DUF3896 16 ekkqqlCkklssltlskkere 36 ek q+l kl+s++ k e FUN_000902-T1 7 EKIQDLQVKLESVKREK---E 24 78899999999886433...3 PP == domain 2 score: -1.0 bits; conditional E-value: 4.2 DUF3896 16 ekkqqlCkklssltls.kke 34 + kq+l +l+ s ke FUN_000902-T1 35 KEKQELETAYGELQTSlSKE 54 55666655555554332222 PP == domain 3 score: 15.1 bits; conditional E-value: 4.1e-05 DUF3896 5 ydynatkkyleekkqqlCkklssltlskkereqlkleidny 45 y+ tkkyleek q+l kl++ +k +eq++ ++++ FUN_000902-T1 122 YNASFTKKYLEEKLQDLQAKLEE---ERKHKEQIQSSLEDF 159 66667***************987...679999998877665 PP == domain 4 score: -1.1 bits; conditional E-value: 4.6 DUF3896 33 kereqlkleidny 45 k +eq++ ++++ FUN_000902-T1 147 KHKEQIQSSLEDF 159 3444444333332 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 36.1 0.00017 0.11 228 392 .. 4 168 .. 2 183 .. 0.86 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00017 CCDC39 228 klaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkke 323 ++ e+i++l+ ++++ k+e e+ ++ +++ ++ +ele el+ +lsk e++ + ee + +l++++ + s l++dl ++ +++e++++ FUN_000902-T1 4 AAGEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDK 99 578999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP CCDC39 324 ieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksq 392 + + +e+ + + +l+ k+ + + ++ +ee+++ l++ leee k++++++ +++ k+ +++ FUN_000902-T1 100 TRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKE 168 999999999999999999999999999999999999999999999999999999999998886543332 PP >> Pam3_gp32 Phage Pam3 gp32-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.2 0.0001 0.067 28 63 .. 43 79 .. 18 84 .. 0.85 2 ? -0.5 0.2 2.6 1.8e+03 45 60 .. 145 160 .. 123 183 .. 0.67 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.0001 Pam3_gp32 28 efGelefllsptkksr.rlkrlleklkekLeefkeeD 63 +Gel+ ls++ + ++++l+++lkekL++f++ FUN_000902-T1 43 AYGELQTSLSKEMERTsSKEELVRQLKEKLAQFQDAN 79 69*****9998877776999*************9873 PP == domain 2 score: -0.5 bits; conditional E-value: 2.6 Pam3_gp32 45 lkrlleklkekLeefk 60 +++ e++++ Le+fk FUN_000902-T1 145 ERKHKEQIQSSLEDFK 160 3444555666666555 PP >> Rod_CreS Crescentin, rod domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 2.6 0.0012 0.78 296 346 .. 9 58 .. 1 64 [. 0.84 2 ? 8.8 18.6 0.0015 1 10 125 .. 67 181 .. 60 184 .] 0.92 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0012 Rod_CreS 296 daaLerAeerieslsdrieeltqrfekeraaleaanrrLleeLeaeraeRa 346 + L+ e+++ +++++ l++ ke+++le+a +L +L +e +eR+ FUN_000902-T1 9 IQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKE-MERT 58 556666778899999****************************998.6776 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0015 Rod_CreS 10 elealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLrae 105 l+++l+q + a+ l r++++ rr ++e++ l+ +++ ++ +++ e ++ ++ + + + ++++l+++l++e+++++++++ l+ ++ FUN_000902-T1 67 QLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKN- 161 6899***********************************************************************************99999876. PP Rod_CreS 106 akaaekalqeaegelatare 125 ++ +ek+ qea+++l+++++ FUN_000902-T1 162 VSKSEKESQEAIQKLQEENR 181 66788999999999998765 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 1.1 0.018 12 35 70 .. 6 41 .. 2 44 .. 0.88 2 ? 7.8 2.6 0.012 8.1 23 85 .. 43 105 .. 38 108 .. 0.92 3 ? 10.0 8.4 0.0024 1.6 9 67 .. 118 177 .. 110 184 .] 0.74 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.018 Occludin_ELL 35 skkfskleeelkslkegskeykkiaeeilqeykklk 70 +k+++l+ +l+s+k++++++++++++i++e ++l+ FUN_000902-T1 6 GEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELE 41 6899**************************988874 PP == domain 2 score: 7.8 bits; conditional E-value: 0.012 Occludin_ELL 23 eYkeLhaeleavskkfskleeelkslkegskeykkiaeeilqeykklkkdpeylekkkrceyL 85 Y eL++ l + ++ s+ ee +++lke+ +++++++ + +++++ + +e +e+k+r L FUN_000902-T1 43 AYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTL 105 6999*******************************************9999999999997655 PP == domain 3 score: 10.0 bits; conditional E-value: 0.0024 Occludin_ELL 9 qreeYkqeFnaey..keYkeLhaeleavskkfskleeelkslkegskeykkiaeeilqeyk 67 + + Y++ F ++y ++ ++L+a+le+ +k+ ++++++l+++k+ sk++k+ +e i+ +++ FUN_000902-T1 118 EGKVYNASFTKKYleEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQ-KLQ 177 56789********4445899**********999999999999988886666666643.333 PP >> LIP-1 Liprin-alpha-like coiled coil domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 28.8 0.00023 0.15 3 162 .. 24 180 .. 22 184 .] 0.84 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00023 LIP-1 3 srvvelqealekqkaelsqa....kervaelsarvaeleeelsaaqkellkaqeanaklqrdlrealaqkedqeerittlEkRylnaqREatslhd 94 ++v l++ + k+k+el +a ++ +++ ++r+++ ee +++ ++ l++ q+an+ l rdl ea ++e++e++ l + qR ++ d FUN_000902-T1 24 EKVDSLNDHIMKEKQELETAygelQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTLGIEEKQR---TISD 116 67778899998999998765222256677788999999*************************************98777655555565...5666 PP LIP-1 95 lndkLEqelankeaalrlsEekvrqlqerlelaeqklaqslkkaeslpeveaelaqrveALskaeerh 162 LE ++ n + + Eek + lq +le ++ +q+ e +v++ ++ eA++k +e + FUN_000902-T1 117 ----LEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEEN 180 ....5667788888889*******************9**99999******************999865 PP >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 31.3 0.00018 0.12 9 138 .. 16 159 .. 7 161 .. 0.76 2 ? 3.0 11.7 0.2 1.3e+02 62 134 .. 129 179 .. 121 184 .] 0.46 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.00018 CENP-F_leu_zip 9 lekLKeserkadsLkdkvenLerelems.eenqekvileaE..nskae.vetlkaeieelaeelrqleldLvtlrsekeeLtke.......Lqkk 92 le K+ ++k dsL+d++ + ++ele++ +e q+++ e+E +sk+e v +lk+++ + + + l+ dL + +++ee++ + +++k FUN_000902-T1 16 LESVKREKEKVDSLNDHIMKEKQELETAyGELQTSLSKEMErtSSKEElVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKtrlltlgIEEK 110 6889**********************87367788999999843478883456********************999666665543222222289** PP CENP-F_leu_zip 93 qervseLesl..nss.lenlleekEqe.kvqmkeeskaaveeLqtqlkel 138 q+++s+Le n s +++ leek q+ +++++ee k+ e++q+ l+++ FUN_000902-T1 111 QRTISDLEGKvyNASfTKKYLEEKLQDlQAKLEEERKH-KEQIQSSLEDF 159 ********852244525789******966666666665.58888887765 PP == domain 2 score: 3.0 bits; conditional E-value: 0.2 CENP-F_leu_zip 62 eelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeeskaaveeLqtq 134 + l+e+l++l+++L++ r+ ke+++++L++ ++ vs + ++es++a+++Lq + FUN_000902-T1 129 KYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKN-VS---------------------KSEKESQEAIQKLQEE 179 345555555555555555555555555554432.22.....................2233333333333333 PP >> ERM_helical Ezrin/radixin/moesin, alpha-helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 12.3 8.5e-05 0.057 47 119 .. 6 78 .. 1 79 [. 0.93 2 ? 1.1 22.1 0.79 5.3e+02 8 100 .. 86 181 .. 72 184 .] 0.83 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 8.5e-05 ERM_helical 47 eeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeeleearee 119 e+ + L+ k + ++eke+ + + +kek++le+ e++ +++ +e kee +++l+e+l + +++ FUN_000902-T1 6 GEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDA 78 566788999999********************************************************99986 PP == domain 2 score: 1.1 bits; conditional E-value: 0.79 ERM_helical 8 kqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek...eqlerelaeaeeeiarleeeke 100 +e +r +++e++t+ ee+++t+ Le k a ++ Le+k q++++++e+ ++++e+ + + ++ + +e +e i++l+ee++ FUN_000902-T1 86 LDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLedfKNVSKSEKESQEAIQKLQEENR 181 567777888999999999999999999999999999999999999999999999999888888877776662225667788899999999999986 PP >> HOOK HOOK protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 11.4 0.0038 2.6 289 365 .. 5 81 .. 1 85 [. 0.79 2 ? 6.2 25.4 0.0077 5.2 257 401 .. 50 180 .. 49 184 .] 0.62 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0038 HOOK 289 eeeklaelqalLedanrrkneLetenrlanqrileLkaqvEelqkalqeqgskaedssllkkkleehleklkeaqee 365 ek+++lq +Le +r+k+++++ n + +eL++ elq++l+++ ++ + +l ++l+e+l + ++a++ FUN_000902-T1 5 AGEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSF 81 46888999999999999999998888888888888888888888888888888888888888888888888888875 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0077 HOOK 257 nlaaelvpaelrekllrLqrENKmLrlkqegseeeklaelqalLedanrrkneLetenrlanqrileLkaqvEelqkalqeqgskaedssllkkkl 352 +l++e+ + +e+l+r +E K q+++ l + L++a+rr++e+e++ rl i e ++ + +l ++k ++s +kk l FUN_000902-T1 50 SLSKEMERTSSKEELVRQLKE-KLA-QFQDAN-----SFLTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDL-------EGKVYNASFTKKYL 131 578899999999999995444.544.333333.....6899***************9998766666666665555.......55555556666666 PP HOOK 353 eehleklkeaqeelqkkkelleelepkldsslkkieeLqeaLkkkdedm 401 ee+l+ l+ ee +k ke+++ +++++ +k +e qea++k +e++ FUN_000902-T1 132 EEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEEN 180 6666666555555555555555555555444444455555555555544 PP >> Nsp1_C Nsp1-like C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 5.7 8.9e-05 0.06 53 109 .. 5 61 .. 3 71 .. 0.87 2 ? 0.7 8.2 0.91 6.1e+02 55 112 .. 112 169 .. 71 182 .. 0.81 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 8.9e-05 Nsp1_C 53 nGeeiskLysevleaeqaqskidqeLdyvesqQdeLeslLdnyEeeleellsklelq 109 Ge+i++L+ + ++++++++k+d d + ++ +eLe+ ++ ++l++ ++++ ++ FUN_000902-T1 5 AGEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSK 61 6************************************99888888887777666554 PP == domain 2 score: 0.7 bits; conditional E-value: 0.91 Nsp1_C 55 eeiskLysevleaeqaqskidqeLdyvesqQdeLeslLdnyEeeleellsklelqnad 112 is+L +v++a +++ ++++L+ ++++ +e + +++ ++le++ + +++++++ FUN_000902-T1 112 RTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKES 169 5799999999999999999999999998888887777777777777777666666554 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 27.4 0.0044 2.9 45 172 .. 17 169 .. 5 180 .. 0.62 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0044 Fez1 45 akleekeeqikeleeslesktlelevceneLqrk...........kneaellrekvgkleeevselreelaelsaeekela.....lesdeakaqr 124 +++++++e++++l++++ + ++ele+ +eLq + ++ + +l+ek+ +++ s l ++l e+ ++++e++ l FUN_000902-T1 17 ESVKREKEKVDSLNDHIMKEKQELETAYGELQTSlskemertsskEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEdktrlL--------- 103 344555666777777777777777777777776633332222222222233445555555555555555555444444444444440......... PP Fez1 125 qea....................eealeslkreverlkaeLkeerqrkeeqaksFeeERrtWqeeKek 172 + + + + l+++++ l+a+L+eer++ke+ ++s e+ +++ ++eKe FUN_000902-T1 104 --TlgieekqrtisdlegkvynaSFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKES 169 ..04444444555566666776566678899****************************999999985 PP >> CC_Bre1 Bre1, coiled-coil containing domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 3.6 0.02 14 84 132 .. 5 53 .. 2 59 .. 0.89 2 ? 5.5 4.7 0.043 29 75 124 .. 53 101 .. 45 111 .. 0.82 3 ? 8.2 8.6 0.0061 4.1 43 105 .. 123 183 .. 101 184 .] 0.76 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.02 CC_Bre1 84 sspdveelqsrlakllaeekelrselerlrsekeqleeqletaserllk 132 + +++++lq +l++ + e + s ++ + +ek++le+ +++ l k FUN_000902-T1 5 AGEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSK 53 66789********************************999999887765 PP == domain 2 score: 5.5 bits; conditional E-value: 0.043 CC_Bre1 75 rllaskrgksspdveelqsrlakllaeekelrselerlrsekeqleeqle 124 + ++ +++++ v++l+++la+ + +++ l l+++ ++e++e++ FUN_000902-T1 53 KE-MERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTR 101 44.566677788899*****************************999865 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0061 CC_Bre1 43 eesflssllfedseefeehLqerskaikslvsrllaskrgksspdveelqsrlakllaeekel 105 ++sf+ + l+e+ +++++ L+e +k+ +++ s+l + +++s++ +e q+ ++kl++e+ e+ FUN_000902-T1 123 NASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSL--EDFKNVSKSEKESQEAIQKLQEENREF 183 68999999************99988766666666..555777777777777777777777665 PP >> CCDC113_CCDC96_CC CCDC113/CCDC96, coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 9.3 0.0048 3.2 105 172 .. 7 76 .. 2 80 .. 0.87 2 ? 6.9 13.1 0.0099 6.6 51 130 .. 100 179 .. 91 184 .] 0.58 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0048 CCDC113_CCDC96_CC 105 eklaklrkelyevklerdklrkqnkklkkqggll..rvPaLleDYdktkeeveekrksvkkLrrkvkile 172 ek+++l+ +l++vk e++k+ n+ + k++ +l + +L + k++e++ +k++ v++L++k+++++ FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELetAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQ 76 68899999999999999999999999988888775579999999999*****************998876 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0099 CCDC113_CCDC96_CC 51 nqalsekieernkeLkrlkkkvtktvhalahlkeklhmlsekleelkkelkerqeklaklrkelyevklerdklrkqnkk 130 + l+ iee++ ++ l +kv + + + l ekl+ l++klee +k +++q l++ + ++ k+ + ++k +++ FUN_000902-T1 100 TRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEE 179 44455556666666666666666666666666666666666666666666666666666655555555555555544433 PP >> FliD_N Flagellar hook-associated protein 2 N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.4 0.53 3.5e+02 17 44 .. 6 33 .. 1 43 [. 0.58 2 ? 10.4 3.4 0.0017 1.1 15 59 .. 43 88 .. 37 111 .. 0.77 3 ? 5.7 4.5 0.049 33 20 54 .. 132 165 .. 116 183 .. 0.71 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.53 FliD_N 17 rapldkleqkktsleakqsaygelkskl 44 +++ l+ k +s++ +++ + +l+ + FUN_000902-T1 6 GEKIQDLQVKLESVKREKEKVDSLNDHI 33 4456666666666666666666666544 PP == domain 2 score: 10.4 bits; conditional E-value: 0.0017 FliD_N 15 aerapldkleqkktsleakqsaygelksklsslqsalsalss.sst 59 a+ ++ l ++ + +++k + +++lk+kl+++q+a s l++ ++ FUN_000902-T1 43 AYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRdLDE 88 555567779**************************88766443444 PP == domain 3 score: 5.7 bits; conditional E-value: 0.049 FliD_N 20 ldkleqkktsleakqsaygelksklsslqsalsal 54 +kl+ +++le++++ ++++s+l+++++ + FUN_000902-T1 132 EEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSK-S 165 567888889999999999999999999998443.2 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 15.7 1.1 7.6e+02 34 126 .. 8 97 .. 6 105 .. 0.41 2 ? 10.5 15.8 0.00062 0.41 35 109 .. 107 181 .. 98 184 .] 0.94 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.1 GAS 34 eiaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknlkarlkelekelkelkwehevleqrfekverErdely 126 +i++l+ k e+ ++e +++++ n ++ ++ +++e eL+ l++ + +s ++l +++l+++l + + ++ l +++ r +e++ FUN_000902-T1 8 KIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEEL---VRQLKEKLAQFQDANSFLTRDLDEADRRNEEME 97 444555555555555555555555555554444444444444444333333333222...233333333333333333333333333333333 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00062 GAS 35 iaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknlkarlkelekelkelkwehe 109 i+e +++ + e ++++++ +k l+e+L+ ++ ++ee +k+ e+ ++ +++kn+ + ke+++ +++l++e++ FUN_000902-T1 107 IEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEENR 181 88999999999************************************************************9986 PP >> CALCOCO1 Calcium binding and coiled-coil domain (CALCOCO1) like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 33.9 0.0042 2.8 49 214 .. 11 179 .. 1 183 [. 0.85 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0042 CALCOCO1 49 aqeaanrqrekekeeykrdreelererkeLesrveelkeelkelrekveelekkqkelealseelaeekdalleqkeesearirELEeDiktltqk 144 ++ +++ +eke+ + +++ +e++eLe el++ l++ e +++ e+ ++l++ ++ ++ ++ l++ +e r E+E+ + lt FUN_000902-T1 11 DLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTLG 106 334445556667777788899999************************************************************************ PP CALCOCO1 145 alekEteLeRlkervkkalaqrkeeeaerkqlqakleqteeElrslskelqelrn...slaqrdtsvlqLqdt 214 ek + l+ +v a +k e+ ++lqakle+ ++ +++ + l++ +n s ++ + +++Lq++ FUN_000902-T1 107 IEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNvskSEKESQEAIQKLQEE 179 *************************************998888777776666665200555555567888876 PP >> NAD_binding_5 Myo-inositol-1-phosphate synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.5 0.061 41 128 162 .. 46 80 .. 16 85 .. 0.80 2 ? 7.5 1.6 0.005 3.4 112 163 .. 112 165 .. 83 168 .. 0.69 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.061 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF NAD_binding_5 128 anqeeradnvlkgkskaeaveqirkdirdFkeknk 162 ++q++ +++ +++sk+e v+q+++ + +F+++n+ FUN_000902-T1 46 ELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANS 80 567888889999999***************99886 PP == domain 2 score: 7.5 bits; conditional E-value: 0.005 xxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx RF NAD_binding_5 112 ekikplp.svyypdfiaanqeeradnvlkgk.skaeaveqirkdirdFkeknkl 163 ++i++l+ vy+ +f ++ ee+ ++++ + +++++ eqi++ ++dFk+ +k FUN_000902-T1 112 RTISDLEgKVYNASFTKKYLEEKLQDLQAKLeEERKHKEQIQSSLEDFKNVSKS 165 445444414888888887777776666543338999*************97765 PP >> COG3_N Conserved oligomeric Golgi complex subunit 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 1.6 0.0032 2.2 23 70 .. 5 52 .. 2 53 .. 0.93 2 ? 6.7 7.5 0.014 9.2 4 57 .. 129 182 .. 125 184 .] 0.93 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0032 COG3_N 23 tlelleeleekfksvsektsslqeaceeLleeqkrleelaeeieekLe 70 + e++++l+ k +sv+ + +++++ +++++e+++le+ + e++++L+ FUN_000902-T1 5 AGEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLS 52 56899**************************************99985 PP == domain 2 score: 6.7 bits; conditional E-value: 0.014 COG3_N 4 dqLeskeeecdelleqtdetlelleeleekfksvsektsslqeaceeLleeqkr 57 + Le+k + ++ le+ ++ +e++++ e+fk+vs+ ++ qea ++L ee+++ FUN_000902-T1 129 KYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEENRE 182 689999999****************************************99987 PP >> NPV_P10 Nucleopolyhedrovirus P10 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 7.0 0.2 1.3e+02 18 53 .. 7 42 .. 3 121 .. 0.87 2 ? 5.3 1.7 0.058 39 39 66 .. 130 157 .. 106 179 .. 0.65 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.2 NPV_P10 18 dkVdalqqqvddleenlpdvtelnekLdaqsaqLae 53 +k++ lq ++++++ + ++v+ ln+++ + ++L++ FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELET 42 799999999999999999999999998777777765 PP == domain 2 score: 5.3 bits; conditional E-value: 0.058 NPV_P10 39 elnekLdaqsaqLaelqtkveeIqdiLn 66 l+ekL+++ a+L+e ++ e+Iq+ L FUN_000902-T1 130 YLEEKLQDLQAKLEEERKHKEQIQSSLE 157 3666777777777766666666666664 PP >> Fib_alpha Fibrinogen alpha/beta chain family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 6.3 0.036 24 35 106 .. 7 74 .. 1 77 [. 0.52 2 ? 9.4 8.7 0.0024 1.6 22 130 .. 29 140 .. 27 141 .. 0.87 3 ? 5.2 4.3 0.045 30 40 113 .. 82 158 .. 73 161 .. 0.75 4 ? 3.7 3.4 0.14 93 29 65 .. 144 180 .. 138 183 .. 0.74 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.036 Fib_alpha 35 kdiekLeneleelsnstkeakelvkaikdslrerqkskkdndnvvkkvskeleeeiaklketvdeqesnirv 106 ++i++L+ +le+++++++++++l +i++ e+q+ ++ + + +ske+e + + +e v + +++++ FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMK---EKQELETAYGELQTSLSKEME-RTSSKEELVRQLKEKLAQ 74 56677777777777776666666666544...333333333455555555565.444444444443354444 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0024 Fib_alpha 22 lqdlllkqekevkkdiekLeneleelsnstkeakelvkaikdslrerqkskkdn...dnvvkkvskeleeeiaklketvdeqesnirvLqevlesn 114 l+d + k ++e+++ +L+ +l++ ++t++ +elv+++k+ l++ q ++ + + ++e+e++ l + e+ ++i L + + + FUN_000902-T1 29 LNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLtrdLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYNA 124 788999**************************************9999887754222445566788999899999999************999999 PP Fib_alpha 115 rqkiqkLeqdidqkee 130 + + Le++ + +++ FUN_000902-T1 125 SFTKKYLEEKLQDLQA 140 9999999999888776 PP == domain 3 score: 5.2 bits; conditional E-value: 0.045 Fib_alpha 40 Leneleelsnstkeakelvkaikdslrerqkskkdn.dnvvkkv..skeleeeiaklketvdeqesnirvLqevles 113 L+++l+e+ ++++e+++ ++ ++ ++e+q++ +d +v++ + +k lee+ + l++++ e+ ++ ++ q+ le+ FUN_000902-T1 82 LTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLeGKVYNASftKKYLEEKLQDLQAKLEEERKHKEQIQSSLED 158 77888889999999999999999999999988888744555543336778888888888888888877777777765 PP == domain 4 score: 3.7 bits; conditional E-value: 0.14 Fib_alpha 29 qekevkkdiekLeneleelsnstkeakelvkaikdsl 65 e++ k++i++ ++++++s+s+ke++e ++++++ FUN_000902-T1 144 EERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEEN 180 5677778888777788888888888888888888765 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 9.7 0.0076 5.1 61 121 .. 7 67 .. 2 73 .. 0.74 2 ? 5.9 4.4 0.032 21 55 107 .. 64 116 .. 58 125 .. 0.83 3 ? 1.6 18.8 0.67 4.5e+02 50 123 .. 108 181 .. 88 183 .. 0.81 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0076 Rab11-FIP3 61 aRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelkeereeerkledklsq 121 +++q l+ ++ + e +++ + +++ +ekq+l+ + el+++l++e+e+ e+ ++q FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQ 67 6788888888888888888888888888888888888888888888888887777666555 PP == domain 2 score: 5.9 bits; conditional E-value: 0.032 Rab11-FIP3 55 elenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelke 107 + +l+++l+q ++ ns L+ ++++ e++e++ + l+ +ee ++++++ FUN_000902-T1 64 LVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISD 116 56788999999999999999999999999999999999999999998888876 PP == domain 3 score: 1.6 bits; conditional E-value: 0.67 Rab11-FIP3 50 RekelelenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelkeereeerkledklsqer 123 ek+ +++ l+ ++ ++ + L+++++ l+a+le+ ++ k+++q+ le++++ k+e+e++ +++ +++r FUN_000902-T1 108 EEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEENR 181 589999999******************************************99999999998887776666665 PP >> Mis12 Mis12 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 12.8 0.015 9.9 106 205 .. 16 120 .. 6 130 .. 0.84 2 ? 7.6 10.6 0.0058 3.9 114 166 .. 127 179 .. 116 183 .. 0.89 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.015 Mis12 106 ld.lsdskeeeeeldeeiealrrkleael.klnraLkaelekneallaelrkllssvselleeee...kkakeelkslkpldetlefllsqlkalq 196 l+ ++ +ke+ +l++ i + +++le++ +l+ L +e+e++++ + +r+l++++++ +++++ ++ e+ + ++ ++++++ l+ +++ q FUN_000902-T1 16 LEsVKREKEKVDSLNDHIMKEKQELETAYgELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSfltRDLDEADRRNEEMEDKTRLLTLGIEEKQ 111 44455557777789999999999999997689999***************************8889998889999999999999999999999888 PP Mis12 197 dkleelksk 205 +++++l+ k FUN_000902-T1 112 RTISDLEGK 120 888887765 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0058 Mis12 114 eeeeldeeiealrrkleaelklnraLkaelekneallaelrkllssvsellee 166 ++ l+e++++l++kle+e+k ++++++ le ++++++ ++ ++ +++l+ee FUN_000902-T1 127 TKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEE 179 45669*********************************************994 PP >> OmpH Outer membrane protein (OmpH-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 13.8 0.0043 2.9 17 89 .. 19 90 .. 2 110 .. 0.64 2 ? 5.0 14.8 0.055 37 9 76 .. 120 182 .. 117 184 .] 0.54 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0043 OmpH 17 gkaaqkqlekefkkrqkelekkekelqklqeklq.aeasels..sekeekekelqkkeqelqeqqqkaqqelqkkq 89 k+ ++++ +++++ + k+++el++ + +lq + ++e++ s kee ++l++k ++q+++ +++l ++ FUN_000902-T1 19 VKREKEKV----DSLNDHIMKEKQELETAYGELQtSLSKEMErtSSKEELVRQLKEKLAQFQDANSFLTRDLDEAD 90 44444444....5555556666666666666666422234555344999999999999999999888888887643 PP == domain 2 score: 5.0 bits; conditional E-value: 0.055 OmpH 9 kileespegkaaqkqlekefkkrqkelekkekelqklqeklqaeasels.sekeekekelqkkeqelqe 76 k++++s k +++l+++++k+++e + ++++q+ e++++ s+ s +e++e+ +qk+++e +e FUN_000902-T1 120 KVYNASFTKKYLEEKLQDLQAKLEEERK-HKEQIQSSLEDFKNV-SK-SeKESQEA---IQKLQEENRE 182 5666666677777777777777776665.555666666777533.22.11224444...5555554443 PP >> PUMA_CC PUMA coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 1.9 0.28 1.9e+02 29 60 .. 7 38 .. 2 51 .. 0.48 2 ? 6.0 11.2 0.025 17 4 67 .. 38 101 .. 35 105 .. 0.87 3 ? 10.8 6.0 0.00079 0.53 13 73 .. 110 167 .. 103 170 .. 0.84 4 ? 0.1 0.4 1.7 1.1e+03 40 58 .. 164 182 .. 154 184 .] 0.59 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.28 PUMA_CC 29 earRrLeKqLadakreianqqkalDdaeRevr 60 e+ L+ +L++ kre ++ D + +e + FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMKEKQ 38 44444444444444444444444444444433 PP == domain 2 score: 6.0 bits; conditional E-value: 0.025 PUMA_CC 4 qqlqrKLknaekqiselktklesaeearRrLeKqLadakreianqqkalDdaeRevrrLedrlr 67 q+l+ ++ +s +++ +s ee R+L +La + + ++ lD+a R +ed+ r FUN_000902-T1 38 QELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTR 101 55555666667788888999*****************************************987 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00079 PUMA_CC 13 aekqiselktklesaeearRrLeKqLadakreianqqkalDdaeRevrrLedrlrasesek 73 ++ is+l+ k+ +a +++ Le +L+d++ ++++ +k+ ++++ Led + s+sek FUN_000902-T1 110 KQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSS---LEDFKNVSKSEK 167 5788*************************************99855...555555555555 PP == domain 4 score: 0.1 bits; conditional E-value: 1.7 PUMA_CC 40 dakreianqqkalDdaeRe 58 + +e ++ ++l + +Re FUN_000902-T1 164 KSEKESQEAIQKLQEENRE 182 4445555666666666665 PP >> TMEM120A-B TMEM120A/B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 7.6 0.00066 0.44 9 91 .. 7 84 .. 2 90 .. 0.73 2 ? 3.0 9.5 0.11 72 25 76 .. 128 181 .. 104 184 .] 0.60 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00066 TMEM120A-B 9 kefkeleetakeykekleelsklqskcskeiskqkkrlkelksslkklkkkvkeeekeaveeleeelkerkaqlkemeallpk 91 +++++l+ + +++k++ e++ +l+++++ke ++ + el++sl+k ++ ++ eel ++lke+ aq+++++++l++ FUN_000902-T1 7 EKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMER-----TSSKEELVRQLKEKLAQFQDANSFLTR 84 567888888888899999999999999999999999999999988886555.....444555555556666667777777665 PP == domain 2 score: 3.0 bits; conditional E-value: 0.11 TMEM120A-B 25 leelsklqskcskeiskqkkrlkelksslkklkkkv..keeekeaveeleeelk 76 + l++ ++++ ++++++k+ ++++ssl+++k+ + ++e++ea+++l+ee + FUN_000902-T1 128 KKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSksEKESQEAIQKLQEENR 181 334555556666666666777777777776666553227788899999998865 PP >> Bacillus_HBL Bacillus haemolytic enterotoxin (HBL) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 4.1 0.0031 2.1 93 150 .. 31 90 .. 23 124 .. 0.77 2 ? 4.3 5.0 0.065 44 99 139 .. 127 167 .. 107 182 .. 0.80 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0031 Bacillus_HBL 93 eavdkkdkaellellekLqeeiqqnqkevkqlieeLkklklklak..dsknF.ktdvdelt 150 + k+k+el ++++Lq+++ + + + ++ e +++lk+kla+ d ++F + d+de++ FUN_000902-T1 31 DHI-MKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQfqDANSFlTRDLDEAD 90 555.689************************************954499998344666665 PP == domain 2 score: 4.3 bits; conditional E-value: 0.065 Bacillus_HBL 99 dkaellellekLqeeiqqnqkevkqlieeLkklklklakds 139 +k+ l e+l++Lq+++ + k+ +q L+++k+ ++++ FUN_000902-T1 127 TKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEK 167 68889999999999999999999999999999998766554 PP >> Sec2p GDP/GTP exchange factor Sec2p # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 16.6 0.0095 6.4 10 126 .. 4 118 .. 1 121 [. 0.87 2 ? 7.6 9.5 0.0084 5.7 4 73 .. 86 157 .. 84 161 .. 0.78 3 ? 2.3 1.7 0.38 2.6e+02 1 31 [. 153 182 .. 153 184 .] 0.66 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0095 Sec2p 10 qlrkelealkerikelesekeeyeelkkkevlveksdlekelkklqakleeekkkreeaekekkklekElEdLTasLFeEANkmVaaar....rek 101 ++ ++++ l+ + +++++eke+ ++l ++ +++ek++le+ + +lq++l++e +++++ e+ +++l++ l ++ F++AN+ + r + FUN_000902-T1 4 AAGEKIQDLQVKLESVKREKEKVDSLNDH-IMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKL---AQ--FQDANSFLTRDLdeadRRN 93 6678899999999***********99999.************************************9766...43..******9885433334999 PP Sec2p 102 eavekknekLkeqLkeketlLeslq 126 e++e k + L+ ++ek+ + +l+ FUN_000902-T1 94 EEMEDKTRLLTLGIEEKQRTISDLE 118 99**************999988765 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0084 Sec2p 4 Ledkleqlrkelealkerikelesekeeyeelkkk..evlveksdlekelkklqakleeekkkreeaekekk 73 L+++ ++ ++ ++ + +e++++++++l+ k +++ k+ le++l+ lqakleee+k++e+++++ + FUN_000902-T1 86 LDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKvyNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLE 157 555555555556666666667788888888888887778889999*********************998765 PP == domain 3 score: 2.3 bits; conditional E-value: 0.38 Sec2p 1 qseLedkleqlrkelealkerikelesekee 31 qs+Led ++ ++e e ++e i++l++e++e FUN_000902-T1 153 QSSLEDFKNVSKSEKE-SQEAIQKLQEENRE 182 6788887777776665.56667777777665 PP >> ATG16 Autophagy protein 16 (ATG16) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 9.3 0.099 66 72 129 .. 22 76 .. 2 84 .. 0.44 2 ? 8.8 18.6 0.0034 2.3 87 183 .. 83 182 .. 80 183 .. 0.87 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.099 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaele 129 +++k+ sl++ + + ++el++a+ gel++ l++ e + +e+ r+ +++la+ + FUN_000902-T1 22 EKEKVDSLNDHIMKEKQELETAY---GELQTSLSKEMERTSSKEELVRQLKEKLAQFQ 76 23444444444444444444443...45555555555555555555555555554444 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0034 ATG16 87 reelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLn.lqlnmaE..eklrklek 179 +l ea r+++e++++ l+ ++e++++++ e ++ +++ +++ leekl+d++++l+e +k e++q l+ + + + E e+ +kl++ FUN_000902-T1 83 TRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEEERKHKEQIQSSLEDFKnVSKSEKEsqEAIQKLQE 178 579*********************************************************************99987513333333113456**** PP ATG16 180 ENke 183 EN+e FUN_000902-T1 179 ENRE 182 **98 PP >> ACR_tran AcrB/AcrD/AcrF family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 9.3 0.017 11 585 738 .. 18 162 .. 3 184 .] 0.54 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.017 ACR_tran 585 kalkekpevesvfavtGfaesgdtagpnsakvfisLkpekerkeeeksvealierlrkelkkipganvellapiq.lreletlsgvrselqvklfg 679 ++ +ek++v+s+ + ++ + +++++sL+ e er + s+e+l+++l+++l+++++an +l+ + ++ ++ l + FUN_000902-T1 18 SVKREKEKVDSLNDHIMK--EKQELETAYGELQTSLSKEMER---TSSKEELVRQLKEKLAQFQDANSFLTRDLDeADRRNEEMEDKTRLLTLGIE 108 444455555555544433..333467778999**********...999*******************99865333022222223333333333333 PP ACR_tran 680 ddleaLseareqllaalkelpelsdvrseqqedqpqlqveidrekaarlGvsisdinqt 738 + + ++s ++ ++ +a +++ l++ + q+++e +r++ +++ s++d++++ FUN_000902-T1 109 EKQRTISDLEGKVYNASFTKKYLEE----K-LQDLQAKLEEERKHKEQIQSSLEDFKNV 162 3344444444444333333333322....2.2223444444555555555555555555 PP >> DUF4515 Domain of unknown function (DUF4515) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 6.9 0.025 17 80 136 .. 2 57 .. 1 62 [. 0.83 2 ? -0.1 10.8 1.5 1e+03 32 97 .. 31 96 .. 23 129 .. 0.67 3 ? 7.1 16.3 0.0097 6.5 43 96 .. 128 182 .. 91 184 .] 0.86 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.025 DUF4515 80 kekqereiqtLeeekkkveaetaekdreahlqflkekalLekqleelkllelgerkt 136 ke +iq+L+ +++v++e ++ d ++ ++kek+ Le el+ + e ++ FUN_000902-T1 2 KEAAGEKIQDLQVKLESVKREKEKVD-SLNDHIMKEKQELETAYGELQTSLSKEMER 57 888899**************987655.79999*********9999988776666555 PP == domain 2 score: -0.1 bits; conditional E-value: 1.5 DUF4515 32 eeierrrqelaskyakqtseLqkqllqkkklqaslkkklkalrqvakikekqereiqtLeeekkkv 97 + i +++qel+ y + +L k+++ +++ +++ l+q++ r+++ ++ ++++ FUN_000902-T1 31 DHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEM 96 568888888888888888888888877665554333333345666655555555555444444444 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0097 DUF4515 43 sky.akqtseLqkqllqkkklqaslkkklkalrqvakikekqereiqtLeeekkk 96 +ky ++ + Lq++l++++k +++++ l ++v+k ++ + iq+L+ee+++ FUN_000902-T1 128 KKYlEEKLQDLQAKLEEERKHKEQIQSSLEDFKNVSKSEKESQEAIQKLQEENRE 182 5552457899***************************99999999*******986 PP >> DUF3450 Protein of unknown function (DUF3450) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 7.9 0.022 15 15 81 .. 6 72 .. 1 74 [. 0.64 2 ? 6.8 9.0 0.0074 5 24 111 .. 57 144 .. 50 148 .. 0.92 3 ? 2.6 3.3 0.15 1e+02 16 48 .. 150 182 .. 145 184 .] 0.84 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.022 DUF3450 15 aatldqvlkeaekavaaaaqsqkkidklddekqellaeyralkaeleslevynkqlerlvasqeqel 81 +++++++ + e+ ++++++ + d + +ekqel+ y +l++ l++ + + e+lv++++++l FUN_000902-T1 6 GEKIQDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGELQTSLSKEMERTSSKEELVRQLKEKL 72 5566666666777777777777777777777777777777777777666666666666666666665 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0074 DUF3450 24 eaekavaaaaqsqkkidklddekqellaeyralkaeleslevynkqlerlvasqeqelasleqqieeierierelvpllekmvdrLeq 111 +++ + +q ++k +++d + l +++ ++ +++e++e + + l+ +++ ++++++le + +++ +++ l+ l+++ ++Le+ FUN_000902-T1 57 RTSSKEELVRQLKEKLAQFQDANSFLTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEGKVYNASFTKKYLEEKLQDLQAKLEE 144 56666777789999**********************************************************************9996 PP == domain 3 score: 2.6 bits; conditional E-value: 0.15 DUF3450 16 atldqvlkeaekavaaaaqsqkkidklddekqe 48 +++++ l+ ++ +++++sq+ i+kl++e +e FUN_000902-T1 150 EQIQSSLEDFKNVSKSEKESQEAIQKLQEENRE 182 6778888889999999999******99999865 PP >> Med9 RNA polymerase II transcription mediator complex subunit 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 6.2 0.17 1.1e+02 14 76 .. 13 76 .. 4 80 .. 0.69 2 ? 2.9 4.9 0.24 1.6e+02 29 77 .. 67 119 .. 49 121 .. 0.76 3 ? 7.6 7.8 0.0083 5.6 20 66 .. 128 181 .. 120 184 .] 0.80 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.17 Med9 14 ekdplsakdldtatgelrhkLqkarelirelpg.idrsveeqeaeieeleeqlakkrelLkkfk 76 + s+k ++++l++ + k ++ +++ g ++ s+ ++ ++ee +++ +e L++f+ FUN_000902-T1 13 QVKLESVKREKEKVDSLNDHIMKEKQELETAYGeLQTSLSKEMERTSSKEELVRQLKEKLAQFQ 76 4444667777777777777777777777777777777777777777777777777777777776 PP == domain 2 score: 2.9 bits; conditional E-value: 0.24 Med9 29 elrhkLqkare....lirelpgidrsveeqeaeieeleeqlakkrelLkkfke 77 +l+ kL ++ + l r+l++ dr ee+e++ + l +++k++ ++++ FUN_000902-T1 67 QLKEKLAQFQDansfLTRDLDEADRRNEEMEDKTRLLTLGIEEKQRTISDLEG 119 5666665555522223578888*************************999875 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0083 Med9 20 akdldtatgelrhkLqkarelirelpg.......idrsveeqeaeieeleeqla 66 k l+ ++++l+ kL++ r++ ++++ +++s +e ++ i++l+e+++ FUN_000902-T1 128 KKYLEEKLQDLQAKLEEERKHKEQIQSsledfknVSKSEKESQEAIQKLQEENR 181 5778899999999998777666666655666888******************97 PP >> HEF_HK HEF_HK domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.2 0.33 2.2e+02 21 58 .. 10 47 .. 3 57 .. 0.71 2 ? 0.2 0.1 2.2 1.5e+03 32 52 .. 56 76 .. 46 84 .. 0.62 3 ? 0.4 0.1 1.9 1.3e+03 23 40 .. 71 85 .. 59 109 .. 0.48 4 ? -1.6 0.0 8.5 5.7e+03 44 51 .. 131 138 .. 106 150 .. 0.58 5 ? 7.5 0.4 0.012 8.1 18 46 .. 150 178 .. 142 182 .. 0.91 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.33 HEF_HK 21 rdslrrLkpwadrnpklaklykelranFehLdgylkll 58 +d +L+++++ ++k ++l + + ++ + L++ + l FUN_000902-T1 10 QDLQVKLESVKREKEKVDSLNDHIMKEKQELETAYGEL 47 55556788888888888888888888888888887544 PP == domain 2 score: 0.2 bits; conditional E-value: 2.2 HEF_HK 32 drnpklaklykelranFehLd 52 +r++ ++l+++l+++ + FUN_000902-T1 56 ERTSSKEELVRQLKEKLAQFQ 76 566666677777776655544 PP == domain 3 score: 0.4 bits; conditional E-value: 1.9 HEF_HK 23 slrrLkpwadrnpklakl 40 +l +++ d+n+ l + FUN_000902-T1 71 KLAQFQ---DANSFLTRD 85 333333...333333333 PP == domain 4 score: -1.6 bits; conditional E-value: 8.5 HEF_HK 44 lranFehL 51 l+++ + L FUN_000902-T1 131 LEEKLQDL 138 33333333 PP == domain 5 score: 7.5 bits; conditional E-value: 0.012 HEF_HK 18 akirdslrrLkpwadrnpklaklykelra 46 ++i++sl+++k++++ +++ ++ +++l++ FUN_000902-T1 150 EQIQSSLEDFKNVSKSEKESQEAIQKLQE 178 79***********************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4508 (0.176473); expected 510.9 (0.02) Passed bias filter: 951 (0.0372284); expected 510.9 (0.02) Passed Vit filter: 200 (0.00782932); expected 25.5 (0.001) Passed Fwd filter: 106 (0.00414954); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 38 [number of targets reported over threshold] # CPU time: 0.60u 0.38s 00:00:00.98 Elapsed: 00:00:00.42 # Mc/sec: 1750.37 // Query: FUN_000903-T1 [L=350] Description: FUN_000903 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-07 29.2 26.0 3.4e-07 29.2 26.0 2.5 2 SCP-1 Synaptonemal complex protein 1 (SCP-1) 3.3e-06 25.8 63.8 4.7e-06 25.3 63.8 1.2 1 CCDC39 Coiled-coil domain-containing protein 39 0.0056 17.3 43.2 0.0062 17.1 16.0 3.3 3 HH_AprE AprE, long alpha-helical hairpin 0.0086 16.2 46.9 0.0086 16.2 46.9 2.4 2 FKBP15 FK506-binding protein 15-like domain ------ inclusion threshold ------ 0.017 15.9 16.6 0.017 15.9 16.6 4.0 2 Rab11-FIP3 Rab11-FIP3-like domain 0.11 13.1 1.0 0.51 11.0 1.0 2.1 1 SCRL Plant self-incompatibility response (SCRL) 0.12 13.2 57.0 0.15 12.9 16.0 3.6 3 OVT1 Major antigen, helical domain 0.25 11.5 62.1 0.062 13.5 12.9 3.8 3 CCDC113_CCDC96_CC CCDC113/CCDC96, coiled-coil 1.8 9.5 62.4 2.6 9.0 27.0 2.3 2 Fez1 Fez1 2.1 8.4 54.8 3.5e+02 1.1 54.4 2.8 1 MscS_porin Mechanosensitive ion channel porin domain 4 8.0 62.4 0.039 14.5 28.9 3.3 2 TPR_MLP1_2 TPR/MLP1/MLP2-like protein 5.2 7.1 60.9 0.07 13.2 22.5 3.4 3 Kazrin Kazrin domain 5.7 6.4 58.6 0.32 10.5 25.4 2.7 2 Rod_CreS Crescentin, rod domain Domain annotation for each model (and alignments): >> SCP-1 Synaptonemal complex protein 1 (SCP-1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 26.0 1.7e-10 3.4e-07 554 689 .. 2 137 .. 1 140 [. 0.89 2 ? 3.0 26.1 0.015 30 658 778 .. 130 252 .. 114 261 .. 0.69 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 1.7e-10 SCP-1 554 rkelkqkrdevkckldkseenarsieyevlkkekqlkilenkcnnlkkqvenkskyieelqqenkalkkkssaeskqlnvyeikvnklelelesak 649 +++++ + +e l+ ++n++s++ e+ +++kql+ e+k++ l+ q+e k+k+ +e+qq+nk+lk k ++ +kq + e + kl el+s+k FUN_000903-T1 2 KEDIRLQDEERDSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSK 97 56777788899999********************************************************************************** PP SCP-1 650 qkfeeiidtyqkeieikkiseeklleevekakvivdeavk 689 ++++e+ ++ + ++ k + + + e+ +i +e vk FUN_000903-T1 98 DQIKELREKLKESNDDLKATRSRSDGVDEQLVAIKEELVK 137 *******999888888887777666666666666666665 PP == domain 2 score: 3.0 bits; conditional E-value: 0.015 SCP-1 658 tyqkeieikkiseeklleevekakvivdeavklqkeidkrcqhkiaemvalmekhkhqydkiveerdselglykskeqeqsslkvaleie.....l 748 + + e+ +k + k+ ee++ k+ ++a+ + +i+ rc++++ e+ a +ek+k + +kiv +++ el l +++ ++s + + e + FUN_000903-T1 130 AIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNRCEKQMNELCATLEKYKLENEKIVAQKERELELLRANALKESQEQHRKQQEeakkhI 225 556677777777889999****************************************************99987654444443333333000002 PP SCP-1 749 snlkaellslkkqlevekeekeklkreake 778 l +e+ lk v+ +++++ ++e e FUN_000903-T1 226 ERLEKEVDRLK---TVQEKDRDRPQHENGE 252 33333333333...3444444444555555 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 63.8 2.4e-09 4.7e-06 262 483 .. 10 239 .. 3 263 .. 0.94 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 2.4e-09 CCDC39 262 kelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaee 357 +e +++++ + ++++l+eel+e +++l++ e++v++l+ ql+ +++ ++ ++++k lk+++++ +k+ +kle + +l ++l++ k++ ++ e FUN_000903-T1 10 EERDSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELRE 105 5667788889999*********************************************************************************** PP CCDC39 358 rakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqell........kqqellynqefqiqq 445 ++ke ++ l++ +r++ +d ++ +ke+l kks+ l +++++ k+++ae ++a ++ ++++++k+ +el+ + ++++ + e +++ FUN_000903-T1 106 KLKESNDDLKATRSRSDGVDEQLVAIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNRCEKQMNELCatlekyklENEKIVAQKERELEL 201 *************************************************************99999999998877776666889999999999999 PP CCDC39 446 lerkvarlkgerseeekeelekkieeLeeeldekkktq 483 l+ + + e++ +++ee +k ie Le+e+d+ k q FUN_000903-T1 202 LRANALKESQEQHRKQQEEAKKHIERLEKEVDRLKTVQ 239 99999999999999999999999999999999988766 PP >> HH_AprE AprE, long alpha-helical hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 5.0 0.001 2 63 109 .. 10 56 .. 6 60 .. 0.90 2 ! 17.1 16.0 3.2e-06 0.0062 50 162 .. 60 176 .. 53 184 .. 0.89 3 ? 2.0 8.3 0.14 2.7e+02 50 94 .. 192 236 .. 179 240 .. 0.85 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.001 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqlalleeelaglre 109 +++++ l+i ++++++l+ee+e+ ++ql++++ ++ l+++l+++ + FUN_000903-T1 10 EERDSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTK 56 67889999**********************************98765 PP == domain 2 score: 17.1 bits; conditional E-value: 3.2e-06 HH_AprE 50 liaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglr...eLlekGlvp.ktrllelerelaelegqiaelrae 141 i++q++ ++++ +++ ++++ l++q ++l++e+++ + q++ lre l+ +++l+++r + ++++lv+ k +l+ +l +e +i e +ae FUN_000903-T1 60 EIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELREKLKESNDDLKATRsrsDGVDEQLVAiKEELVKKSTALLKIEEEIKEVKAE 155 5899****************************************************99944458899998757889999999************** PP HH_AprE 142 iararqqiaeaelqiaqlrae 162 ++a + ++++++ ++ +e FUN_000903-T1 156 KEKALEDKEDIQNRCEKQMNE 176 **********99998876665 PP == domain 3 score: 2.0 bits; conditional E-value: 0.14 HH_AprE 50 liaaqrqlfearraalagelailqeqieqleeeieglraqlaalr 94 +++++r+l r++al++++++ ++q e+++++ie l++++++l+ FUN_000903-T1 192 VAQKERELELLRANALKESQEQHRKQQEEAKKHIERLEKEVDRLK 236 45668888888999************************9999886 PP >> FKBP15 FK506-binding protein 15-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 46.9 4.4e-06 0.0086 53 222 .. 11 179 .. 7 181 .. 0.78 2 ? -4.5 16.6 9.4 1.9e+04 78 146 .. 185 254 .. 178 271 .. 0.51 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 4.4e-06 FKBP15 53 qsnlllEqrndslkstaeqsqar...vleleqekvk.lteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveelee 144 ++ ++lE +d ++s e+ ++r + ++ ++kvk l+++L+a t+q +e+q++ ++l+ k + +++ ++++++++k ++el++ + q +el+e FUN_000903-T1 11 ERDSTLEIEKDNVQSLKEELEERnkqLETA-EDKVKcLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELRE 105 555666666665555555444441104444.45665388999999999999999999999999999999999999999999999999999999999 PP FKBP15 145 kveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerkrleeeleelkksleeeiqsLre 222 k++e++++lk+ + ++ ++e+l +++eel + + +++ k +++e++++ e+ e++++++e+++++L + FUN_000903-T1 106 KLKESNDDLKATRSRSDGVDEQLVAIKEELVKKSTALLK----IEEEIKEVKAEKEKALEDKEDIQNRCEKQMNELCA 179 999999999999999999999999999998644444444....56666677799999999999999999999999865 PP == domain 2 score: -4.5 bits; conditional E-value: 9.4 FKBP15 78 eleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraq.veeleekv 146 +le+ek+ ++e + + l++ ++++k+++e +++++ +++e ++ k+ ek r + ++e+ e v FUN_000903-T1 185 KLENEKIVAQKERELELLRANALKESQEQHRKQQEEAKKHIERLEKEVDRLKTVQEKDRDRpQHENGEAV 254 4555555555555555555555555555555555555555555555555555444433332133333344 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 8.8 0.01 20 81 124 .. 13 56 .. 2 57 .. 0.78 2 ? 15.9 16.6 8.7e-06 0.017 54 123 .. 49 118 .. 48 120 .. 0.95 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.01 Rab11-FIP3 81 kaqlerleeekqklqdeleelslelkeereeerkledklsqere 124 ++le +++ q+l++elee +++l++++++ + l+d+l+++ + FUN_000903-T1 13 DSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTK 56 46677778889999999999999999999999999999988765 PP == domain 2 score: 15.9 bits; conditional E-value: 8.7e-06 Rab11-FIP3 54 lelenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdeleelslelkeereeerkledklsqer 123 +le +++ +++++ n++L+s+++ +q+++le +k kl++el++ + ++ke re+ ++ +d+l++ r FUN_000903-T1 49 DQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELREKLKESNDDLKATR 118 689999999********************************************************99887 PP >> SCRL Plant self-incompatibility response (SCRL) protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 1.0 0.00026 0.51 6 42 .. 148 184 .. 145 193 .. 0.86 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00026 SCRL 6 hvqeveankkkrCkrkqtfpGkCgndgkktCvkdlkk 42 ++ev+a+k+k + k+ ++ +C+++ ++ C+++ k FUN_000903-T1 148 EIKEVKAEKEKALEDKEDIQNRCEKQMNELCATLEKY 184 689****************************987665 PP >> OVT1 Major antigen, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 19.4 0.00023 0.45 18 94 .. 10 86 .. 5 92 .. 0.94 2 ? 12.9 16.0 7.8e-05 0.15 6 93 .. 82 169 .. 81 176 .. 0.94 3 ? -1.6 10.6 2.6 5e+03 36 78 .. 195 237 .. 168 263 .. 0.55 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00023 OVT1 18 eekdaalknleelkrkllkdlenqrarldavtseldklqteyesatkntvaieqtvkElkqqrDeiskqkdelsrqL 94 ee+d++l+ ++ ++l ++le+ ++l++ + + lq ++e++tk++ i+q++k lk++ +kq d+l+ q FUN_000903-T1 10 EERDSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQK 86 89**********************************************************************99885 PP == domain 2 score: 12.9 bits; conditional E-value: 7.8e-05 OVT1 6 lEneYnsllrkleekdaalknleelkrkllkdlenqrarldavtseldklqteyesatkntvaieqtvkElkqqrDeiskqkdelsrq 93 lE++ +l ++l +++k+l+e ++ +dl r+r d v ++l +++e+ +++ + ie ++kE+k +++ +k++++ + FUN_000903-T1 82 LETQKSKLSKELSSSKDQIKELREKLKESNDDLKATRSRSDGVDEQLVAIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNR 169 7888889999999999*******************************************************************99765 PP == domain 3 score: -1.6 bits; conditional E-value: 2.6 OVT1 36 kdlenqrarldavtseldklqteyesatkntvaieqtvkElkq 78 k+ e + r +a+++ ++ +++ e+a+k++ +e++v lk+ FUN_000903-T1 195 KERELELLRANALKESQEQHRKQQEEAKKHIERLEKEVDRLKT 237 3333333344444444444444444444444444444444443 PP >> CCDC113_CCDC96_CC CCDC113/CCDC96, coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 26.0 0.00064 1.3 49 136 .. 21 108 .. 12 112 .. 0.94 2 ? 13.5 12.9 3.2e-05 0.062 53 136 .. 88 171 .. 87 172 .. 0.95 3 ? -0.5 16.2 0.61 1.2e+03 58 126 .. 174 244 .. 171 250 .. 0.62 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00064 CCDC113_CCDC96_CC 49 ienqalsekieernkeLkrlkkkvtktvhalahlkeklhmlsekleelkkelkerqeklaklrkelyevklerdklrkqnkklkkqgg 136 ++q+l+e++eernk+L+ +kv+ +l+ ++ ++++++++++lk+++ + +++ +kl+ + +++ +e + ++q+k+l++++ FUN_000903-T1 21 DNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELREKLK 108 5799********************************************************************************9986 PP == domain 2 score: 13.5 bits; conditional E-value: 3.2e-05 CCDC113_CCDC96_CC 53 alsekieernkeLkrlkkkvtktvhalahlkeklhmlsekleelkkelkerqeklaklrkelyevklerdklrkqnkklkkqgg 136 +ls+++ + ++++k+l++k + + l+ ++ + + ++e+l + k+el ++ + l k+++e++evk e++k+ +++++++ +++ FUN_000903-T1 88 KLSKELSSSKDQIKELREKLKESNDDLKATRSRSDGVDEQLVAIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNRCE 171 588889999999******************************************************************999876 PP == domain 3 score: -0.5 bits; conditional E-value: 0.61 CCDC113_CCDC96_CC 58 ieernkeLkrlkkkvtktvhalahlke..klhmlsekleelkkelkerqeklaklrkelyevklerdklrk 126 ++e ++ L++ k+ k v + + e ++++l+e +e+++k+ +e ++++++l+ke+ ++k++ +k r+ FUN_000903-T1 174 MNELCATLEKYKLENEKIVAQKERELEllRANALKESQEQHRKQQEEAKKHIERLEKEVDRLKTVQEKDRD 244 45555555555555555544444443322356777888888888888888888888888888888877765 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 27.0 0.0013 2.6 37 153 .. 6 122 .. 2 127 .. 0.84 2 ? 5.8 28.0 0.012 24 32 153 .. 127 247 .. 124 267 .. 0.81 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0013 Fez1 37 raqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeeale 132 r q e ++le +++++++l+e+le+++++le+ e++++ +++ e +++++++++ + l+++++++++++++l++++++ ++ ++++++++ FUN_000903-T1 6 RLQDEERDSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIK 101 555567778899999999**************************99999999*************9999988888887777777777777788888 PP Fez1 133 slkreverlkaeLkeerqrke 153 +l++++++ + Lk+ r r++ FUN_000903-T1 102 ELREKLKESNDDLKATRSRSD 122 888888888888888887765 PP == domain 2 score: 5.8 bits; conditional E-value: 0.012 Fez1 32 eivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqea 127 ++va++ +l +++l + ee+ike++++ e+ + e ++n+ ++++ne + ek + +e++ +e el + +++l+ ++++ ++q++ea FUN_000903-T1 127 QLVAIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNRCEKQMNELCATLEKYKLENEKIVAQKERELELLR-ANALKESQEQHRKQQEEA 221 68999999999999999************99999999************9999999888777777777775555433.444555555566777778 PP Fez1 128 eealeslkreverlkaeLkeerqrke 153 ++++e l++ev+rlk+ +++r+r + FUN_000903-T1 222 KKHIERLEKEVDRLKTVQEKDRDRPQ 247 999************98877777654 PP >> MscS_porin Mechanosensitive ion channel porin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 54.4 0.18 3.5e+02 22 230 .. 26 262 .. 10 269 .. 0.70 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.18 MscS_porin 22 LqqAlsf.leeadeqkekaeayqqaledaPaeirelrqelaal.kkkaeeesaeilsslsleeLeqrLlqesaqlqdlqeqlaqlnsqlrelqtrp 115 L++ l+ ++ + +++k + +q++le ++++e++q+ ++l +k ++ +++++ ++ + L ++L+ ++q +l+e+l++ n++l ++++r FUN_000903-T1 26 LKEELEErNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLkSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELREKLKESNDDLKATRSRS 121 444433302334556778999999999999999999999999944444455555555666789999999999999999999999999999999999 PP MscS_porin 116 eraqqqlteakqrlqeienqL.......nalaasge..........alseaqrvalqaeqaalkaqie......mleqellsnsnr...qdLlklr 185 + +ql + k++l + ++ L + +a++e + e q ++l a ++ +k+++e ++e+ell ++++ q+ +++ FUN_000903-T1 122 DGVDEQLVAIKEELVKKSTALlkieeeiKEVKAEKEkaledkediqNRCEKQMNELCATLEKYKLENEkivaqkERELELLRANALkesQEQHRKQ 217 9999999999888776644444444433333333334333444455555788899999999999998533333389********98444667899* PP MscS_porin 186 rdllalriarleqeiqaLqellnekRlqeaekavaeterlaeeaa 230 +++++++i+rle+e++ L++++ R + ++ ++ l ++a+ FUN_000903-T1 218 QEEAKKHIERLEKEVDRLKTVQEKDRDRPQHENGEAVAYLNNQAE 262 *********************999996555544444444444443 PP >> TPR_MLP1_2 TPR/MLP1/MLP2-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 28.9 2e-05 0.039 2 111 .. 22 138 .. 21 144 .. 0.65 2 ? -2.6 26.0 3.7 7.2e+03 6 102 .. 145 247 .. 140 264 .. 0.60 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 2e-05 TPR_MLP1_2 2 elksleseikrlkeekeeaeeklqklqedlekqaeiakeaqqkYer...elvkhaeavkelqalreel....nelkaeiaelkaeaesakaelees 90 +++sl++e+++ +++ e ae+k++ lq++le+++++ake qq+ ++ ++ h +++ +l++ +++l ++ k++i+el++++++ + +l++ FUN_000903-T1 22 NVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTlksKMTSHTKQTDKLETQKSKLskelSSSKDQIKELREKLKESNDDLKAT 117 5789***********************************999866511156666666666644333222222555666666666666666666666 PP TPR_MLP1_2 91 eesweeqkeelekelselekr 111 ++ e+l ++el k+ FUN_000903-T1 118 RSRSDGVDEQLVAIKEELVKK 138 655555555555555555554 PP == domain 2 score: -2.6 bits; conditional E-value: 3.7 TPR_MLP1_2 6 leseikrlkeekeeaeeklqklqedlekqaeiakeaqqkYerelvk.haeavkel.....qalreelnelkaeiaelkaeaesakaeleeseeswe 95 +e+eik++k+eke+a e + +q+ +ekq +++ + +kY+ e k a+ +el +al+e ++ +++ +e+k+ +e++++e+++ + e FUN_000903-T1 145 IEEEIKEVKAEKEKALEDKEDIQNRCEKQMNELCATLEKYKLENEKiVAQKERELellraNALKESQEQHRKQQEEAKKHIERLEKEVDRLKTVQE 240 678888888888888888888888888888888888888865543322333333400011334444455566666666666666666665555555 PP TPR_MLP1_2 96 eqkeele 102 + +++ + FUN_000903-T1 241 KDRDRPQ 247 5555555 PP >> Kazrin Kazrin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 14.7 0.021 42 126 188 .. 9 74 .. 3 75 .. 0.80 2 ? 13.2 22.5 3.6e-05 0.07 5 107 .. 74 183 .. 70 190 .. 0.73 3 ? 3.4 6.9 0.037 73 3 75 .. 211 281 .. 208 286 .. 0.71 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.021 Kazrin 126 sdesvkqlakekeelErekwellrrard...aaerslsLraqldakeqqlkeleeelaeakrqlas 188 +e + l ek+++ k el r ++ a++++ L++ql+ak +q ke++++ + +k++++s FUN_000903-T1 9 DEERDSTLEIEKDNVQSLKEELEERNKQletAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTS 74 45666788999999999888888777643326677789***********************99876 PP == domain 2 score: 13.2 bits; conditional E-value: 3.6e-05 Kazrin 5 eeeeeiakLreenerLqaeverlrkeleelkkeaeeeleslesaea...lsaesaselkvqltqleqeLarakealqalkaDrkrLkaekldLln. 96 +++++++kL+ ++++L +e+++ + +++el+++++e+ ++l+ +++ e+ ++k +l ++++ L + e ++ +ka++ + ++k d+ n FUN_000903-T1 74 SHTKQTDKLETQKSKLSKELSSSKDQIKELREKLKESNDDLKATRSrsdGVDEQLVAIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNr 169 556666777777777777777666666666666554444433332211134467788999********************************9866 PP Kazrin 97 ...QmkqLyatLed 107 Qm +L+atLe+ FUN_000903-T1 170 cekQMNELCATLEK 183 666*********97 PP == domain 3 score: 3.4 bits; conditional E-value: 0.037 Kazrin 3 seeeeeeiakLreenerLqaeverlrkeleelkkeaeeeleslesaealsaesaselkvqltqleqeLarake 75 +e++++++++ ++ erL++ev+rl+ e+ +++ + e+ e ++l+++ +++++ l++ +L++a FUN_000903-T1 211 QEQHRKQQEEAKKHIERLEKEVDRLKTVQEKDRDRPQ--HENGEAVAYLNNQAEEKMSTSLHAPLPDLESALS 281 456667778889999**********999887666664..4455666667777777777777777777776655 PP >> Rod_CreS Crescentin, rod domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 25.4 0.00016 0.32 10 178 .. 11 130 .. 2 135 .. 0.54 2 ? 5.6 25.7 0.0049 9.6 85 200 .. 114 231 .. 111 245 .. 0.88 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00016 Rod_CreS 10 elealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLrae 105 e + le e + ++l++e+++ +++l +ae++++ l+ +l++ ++ ke +++++ l++++ t + +lE+q + +++ + + + k Lr++ FUN_000903-T1 11 ERDSTLEIEKDNVQSLKEELEERNKQLETAEDKVKCLQDQLEAKTKQAKEIQQQNKTLKSKMTSHTKQTDKLETQKSKLSKELSSSKDQIKELREK 106 334455555555666666666666666666666666666666666666666666666666666666666666666666666666666666666666 PP Rod_CreS 106 akaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaa 178 +k ++ +l + + + + e+ L+a FUN_000903-T1 107 LKESNDDLKATRSRSDGVDEQ-------------------------------------------------LVA 130 666666555555555555554.................................................444 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0049 Rod_CreS 85 lkaeteqnraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaael.aelearlaeletaldaerarlralegq.Laa 178 lka + ++ + e+l a ++e+ + +al + e+e+++++ +++ + ++++ +q++ e+q el a le e+e+ ++++ + l+ l ++ L + FUN_000903-T1 114 LKATRSRSDGVDEQLVAIKEELVKKSTALLKIEEEIKEVKAEKEKALEDKEDIQNRCEKQMNELcATLEKYKLENEKIVAQKERELELLRANaLKE 209 7888899999*****************************************************9345666677***************99762667 PP Rod_CreS 179 eqaereraeaqleeevealraE 200 q+++ ++++++++ +e+l+ E FUN_000903-T1 210 SQEQHRKQQEEAKKHIERLEKE 231 7788888888888889988877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (350 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5434 (0.212723); expected 510.9 (0.02) Passed bias filter: 914 (0.03578); expected 510.9 (0.02) Passed Vit filter: 378 (0.0147974); expected 25.5 (0.001) Passed Fwd filter: 165 (0.00645919); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 1.06u 0.42s 00:00:01.48 Elapsed: 00:00:00.48 # Mc/sec: 2926.33 // Query: FUN_000904-T1 [L=84] Description: FUN_000904 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (84 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 411 (0.0160893); expected 510.9 (0.02) Passed bias filter: 292 (0.0114308); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 865.87 // Query: FUN_000905-T1 [L=745] Description: FUN_000905 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-26 91.5 0.0 2.3e-25 89.9 0.0 1.8 1 Peptidase_M28 Peptidase family M28 1.1e-15 58.2 0.2 1.9e-15 57.4 0.2 1.4 1 TFR_dimer Transferrin receptor-like dimerisation domain 2.8e-12 47.1 0.0 5.8e-12 46.1 0.0 1.6 1 PA PA domain 0.0041 17.5 0.0 0.0087 16.5 0.0 1.5 1 Peptidase_M20 Peptidase family M20/M25/M40 ------ inclusion threshold ------ 0.079 12.1 0.0 0.13 11.3 0.0 1.2 1 AcnX Aconitase X 0.13 12.4 0.3 0.23 11.6 0.3 1.3 1 BRCA-2_OB3 BRCA2, oligonucleotide/oligosaccharide-bindin 1.3 9.8 3.7 0.58 10.9 0.7 1.9 2 Retrotrans_gag Retrotransposon gag protein Domain annotation for each model (and alignments): >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 89.9 0.0 6.3e-29 2.3e-25 1 175 [. 360 558 .. 360 565 .. 0.91 Alignments for each domain: == domain 1 score: 89.9 bits; conditional E-value: 6.3e-29 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaa...skqqpkrsvrflffdaEEagllGSkafak..skpelkkiravl 90 Nv++ ++g+++ de ++l+ H D + GA D sg+aa++el+rvl + ++++pkr+++fl ++aEE GS + + s+ +++ +a+l FUN_000905-T1 360 NVVGVIEGTTHpDELVMLGNHRDAWI--FGAADPSSGTAAMMELSRVLGEqlkKGWRPKRTIVFLSWGAEEPQYMGSVEWLEeySRLLSARAVAYL 453 9**********9*************9..7********************977778899***********************985555********* PP Peptidase_M28 91 nlDmigsggkallf.................qsgpktsselekylkaaakpvgktlaedpfqergipgrsDhapfa.kagipaldl.....aetkf 163 n+Dm g+ + s +++s++ ++++++++++g ++ ++++q r+ sD++ f+ + gip++d+ ++t+ FUN_000905-T1 454 NVDMSVDGNYSFRAksaplmdwvlakatmkvPSPLGNESAFDEWIRKLPNTLGMNYLPKLQQPRA---GSDYVNFIqRLGIPIVDIrytynSKTSS 546 *********99999999999999999988887778889999999999999999999888888766...9*******5667*********9999999 PP Peptidase_M28 164 keryHtpkDtld 175 ++ yHt +D++ FUN_000905-T1 547 NPLYHTVHDNFW 558 *********986 PP >> TFR_dimer Transferrin receptor-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.4 0.2 5.2e-19 1.9e-15 3 120 .. 626 739 .. 624 740 .. 0.92 Alignments for each domain: == domain 1 score: 57.4 bits; conditional E-value: 5.2e-19 TFR_dimer 3 leplkkaiekfkkaaeefdkwakkweevveasgkessllavrevNdklmlferafldpeg.lpgrpwfkHvvfapglwtgyagatFPgirdaiea. 96 l+ l++a++kf+++a++fd++++k + ++++ vr++N++l ++er+f++ e l++ p +Hvv + + y + + g++dai++ FUN_000905-T1 626 LNFLDQAVQKFQETAKKFDQYVEKAN--------KEDEAIVRKINNRLLNVERSFINLEPiLQDFPLQRHVVLTHSPSIRY--NWYGGVVDAIFRa 711 7889********************77........789999*******************8588**********97776446..99*********99 PP TFR_dimer 97 ....gdweeaqkqisivakaiekaaesL 120 e ++kqisiv++ i++a++ L FUN_000905-T1 712 rkglLTSEDVKKQISIVSYGINSATHVL 739 99997899*****************998 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.1 0.0 1.6e-15 5.8e-12 1 93 [. 175 264 .. 175 266 .. 0.89 Alignments for each domain: == domain 1 score: 46.1 bits; conditional E-value: 1.6e-15 PA 1 vtgplVaapndgceasdgssedf........dvkGkivLvqrGectfaeKvrnAqaaGAagviiynnveg.glgapteaggeeleadpitiPavgi 87 v+g+lV +a++g++edf +++Gkiv+++ G+ +a+K++ A++ GA+g+i y ++++ + + g ++ ++ +++P++ + FUN_000905-T1 175 VKGKLV-------YANYGREEDFkaleklgvNCSGKIVIMRYGKIGRATKSKRAHKLGAIGAIYYMDPQEyA---RK--GVDKVFPNYNWMPSTAV 258 789***.......899**99999*******************************************996653...23..445677889******** PP PA 88 skadge 93 ++++ + FUN_000905-T1 259 QRGNIK 264 *98865 PP >> Peptidase_M20 Peptidase family M20/M25/M40 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 2.4e-06 0.0087 32 186 .. 387 556 .. 381 584 .. 0.63 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 2.4e-06 xxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx........ RF Peptidase_M20 32 Ghddhkggllaalealralkee...glkpkgtvkllfqpdEEggsgGakalie...gllekekvdavfglhigeptlle.gkigigvg........ 112 G++d +g +a++e+ r l e+ g +pk+t+++l +++EE + +G+ + +e ll + av l + +++ g+ +++ + FUN_000905-T1 387 GAADPSSGTAAMMELSRVLGEQlkkGWRPKRTIVFLSWGAEEPQYMGSVEWLEeysRLL---SARAVAYLNVD---MSVdGNYSFRAKsaplmdwv 476 78888888899988877666653337789*************54499977777454433...34443334444...44445666667766666443 PP ..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxx..xxxxxxxxx...xxxxx....xxxxx.xxx RF Peptidase_M20 113 ..eveveelergapvlvndselvkalreaakellgee..velevsgvmggeDaaff..aagvptvvi...lGpgs....glahs.hnE 186 +++ ++ +++l n+s++ + +r++ l g + ++l+ + +g+D f ++g+p v i + ++ l+h+ h+ FUN_000905-T1 477 laKAT----MKVPSPLGNESAFDEWIRKLPNTL-GMNylPKLQQPR--AGSDYVNFiqRLGIPIVDIrytYN-SKtssnPLYHTvHDN 556 32222....556666666777777777777665.666324444333..666655554777888764443333.212346777774444 PP >> AcnX Aconitase X # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 3.7e-05 0.13 172 252 .. 332 407 .. 330 421 .. 0.89 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 3.7e-05 AcnX 172 eyGlhldenRkptvlveveaesedeadygllGylvGklagdriPvlkglekpskdelKalgAalaasgsvalfhiegvtPe 252 yG+ + en tvl++v e+ + y+++G++ G++++d+ +l +++++ +gAa +sg++a++ ++ v e FUN_000905-T1 332 TYGVEMAENDTRTVLLNVTNENYEADVYNVVGVIEGTTHPDELVMLG-----NHRDAWIFGAADPSSGTAAMMELSRVLGE 407 59*****************999999*****************99998.....567899***************99988777 PP >> BRCA-2_OB3 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.3 6.3e-05 0.23 49 134 .. 572 655 .. 553 660 .. 0.86 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 6.3e-05 BRCA-2_OB3 49 llavkfwsdleeyaledivkpraLiaasNLqwrressskvptlyagelsvfsanPkeehlqealnklknlvedqeafleeaeekls 134 ++ ++w++l +++ d v ++ +++r e + ++ +++ +++ a+ ++l++a++k++++ ++ ++++e+a+++ + FUN_000905-T1 572 QVTTRVWTELT-MTFADAVILPLNVTHYGVNLR-EYTLRIKRSFVEDFANHNASNELNFLDQAVQKFQETAKKFDQYVEKANKEDE 655 46678999999.888888888888999999999.7778*******************************************98755 PP >> Retrotrans_gag Retrotransposon gag protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.1 5.5 2e+04 26 37 .. 575 586 .. 559 588 .. 0.68 2 ? 10.9 0.7 0.00016 0.58 30 90 .. 603 660 .. 594 665 .. 0.90 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 5.5 Retrotrans_gag 26 iesWdelkkafl 37 + W+el++ f FUN_000905-T1 575 TRVWTELTMTFA 586 458999999886 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00016 Retrotrans_gag 30 delkkaflkkfvpserkdeleeelrslrQgtesvreYverFkrlarqlpeevldeealiea 90 +e++ + +++fv++ + + + +el l Q+ ++++e ++F++++ +++ ++ea++++ FUN_000905-T1 603 REYTLRIKRSFVEDFANHNASNELNFLDQAVQKFQETAKKFDQYVEKAN---KEDEAIVRK 660 5788899999**999**********************************...788888877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (745 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1319 (0.0516344); expected 510.9 (0.02) Passed bias filter: 1038 (0.0406342); expected 510.9 (0.02) Passed Vit filter: 122 (0.00477589); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.40 # Mc/sec: 7510.63 // Query: FUN_000906-T1 [L=116] Description: FUN_000906 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 677 (0.0265023); expected 510.9 (0.02) Passed bias filter: 439 (0.0171854); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1179.46 // Query: FUN_000907-T1 [L=430] Description: FUN_000907 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (430 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 622 (0.0243492); expected 510.9 (0.02) Passed bias filter: 446 (0.0174594); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4332.21 // Query: FUN_000908-T1 [L=552] Description: FUN_000908 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-75 252.0 1.0 6.5e-75 251.5 1.0 1.2 1 FAD_binding_7 FAD binding domain of DNA photolyase 3.3e-41 141.5 0.0 8.3e-41 140.2 0.0 1.7 2 DNA_photolyase DNA photolyase ------ inclusion threshold ------ 0.16 11.8 1.1 0.38 10.6 1.1 1.5 1 zf-WIZ Zinc finger found in WIZ protein Domain annotation for each model (and alignments): >> FAD_binding_7 FAD binding domain of DNA photolyase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 251.5 1.0 7.6e-79 6.5e-75 3 202 .. 311 508 .. 308 509 .. 0.95 Alignments for each domain: == domain 1 score: 251.5 bits; conditional E-value: 7.6e-79 FAD_binding_7 3 sellwrefyyqllaaepeleeknlkeefdeipweedeedekleaWkeGrTGyPivDAamrqLratGwmhnrlRmivasFltk.dLlidWregaevf 97 ++llwref+++++a++p++ + + ++ + +ipw+ ++ e+l++W++G+TG+P++DA+m qL+++Gw+h+++R++v +Flt+ dL+i+W+eg++vf FUN_000908-T1 311 GQLLWREFFFTVAANNPNFDQMDENPVCLQIPWTANP--EWLKKWEQGQTGFPWIDAIMVQLKQEGWIHHLARHAVGCFLTRgDLWISWEEGMKVF 404 79*****************77777777777***6554..59******************************************************* PP FAD_binding_7 98 aellvDadlainaggwqwvagtgadaapyfrifnpvkqgekfDpdgeyirrwvPelaklpakyihepwkaeaeeqkkagvelgkdYpkpivdhkea 193 +++l+Da+++ nag+w+w++++ + ++ +f +++pv +g+k+Dp+g+y+r+++P l+ +pakyih+pw+a++++q++a++ +gkdYp+pivdh++ FUN_000908-T1 405 ERWLLDAEWSLNAGNWMWLSCSAFFQQ-FFNCICPVGFGRKLDPNGDYVRKYLPVLKGFPAKYIHAPWTAPENVQRAARCIIGKDYPRPIVDHHKV 499 *********************888887.9******************************************************************* PP FAD_binding_7 194 rkralealk 202 ++++le+++ FUN_000908-T1 500 STANLEKMR 508 *****9997 PP >> DNA_photolyase DNA photolyase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 140.2 0.0 9.8e-45 8.3e-41 1 154 [. 29 183 .. 29 194 .. 0.94 2 ? -3.2 0.0 1.2 1e+04 122 142 .. 461 481 .. 458 484 .. 0.76 Alignments for each domain: == domain 1 score: 140.2 bits; conditional E-value: 9.8e-45 DNA_photolyase 1 vlvWfrrDlRlhDNpALaaAaasgaplipvfvldpaeerklkvgaarrrfllesLadLdeelrergirLvvrrgdpadvlpelakelgasavvan 95 +++W+r+DlRlhDNp L++A+++++++ +++vld++ +++ +g + +rfll+sL+d+d++lr++++rL+v+rg+padv+p+l++e++ s ++++ FUN_000908-T1 29 AIHWVRKDLRLHDNPSLLEAVKGSDTVRIIYVLDTKVDHATGIGLNLWRFLLQSLEDVDDSLRKLNSRLFVVRGQPADVFPRLFREWKTSFLTFE 123 59**********************************5566667**************************************************** PP DNA_photolyase 96 reyepderrrdeavkealeeagvevesfdghllvppgev.rtkkgkpykvftpfikavlk 154 ++ ep++r+ d+a++ ++e+gvev +h+l++p+ + + ++g+++ ++++f v++ FUN_000908-T1 124 EDSEPFGREKDAAIRLLAQESGVEVAVGRSHTLYDPQLIiKHNSGTAPLTYKKFLAIVRS 183 ***************************************899999*********997776 PP == domain 2 score: -3.2 bits; conditional E-value: 1.2 DNA_photolyase 122 sfdghllvppgevrtkkgkpy 142 f++++++ p++++ + + ++ FUN_000908-T1 461 GFPAKYIHAPWTAPENVQRAA 481 688999*****9987766555 PP >> zf-WIZ Zinc finger found in WIZ protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 1.1 4.5e-05 0.38 22 32 .. 372 382 .. 371 384 .. 0.94 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 4.5e-05 zf-WIZ 22 QEdWikHLqrH 32 QE Wi HL rH FUN_000908-T1 372 QEGWIHHLARH 382 9********** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (552 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 645 (0.0252496); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 5298.71 // Query: FUN_000909-T1 [L=187] Description: FUN_000909 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-20 72.5 0.8 4.9e-20 71.9 0.8 1.4 1 CDI Cyclin-dependent kinase inhibitor Domain annotation for each model (and alignments): >> CDI Cyclin-dependent kinase inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.9 0.8 1.9e-24 4.9e-20 1 48 [. 36 83 .. 36 84 .. 0.98 Alignments for each domain: == domain 1 score: 71.9 bits; conditional E-value: 1.9e-24 CDI 1 nlfgpvdheeleeffqaalreqqerfseKWNFDFvndtPLeGryeWer 48 nlfgpvdhe+l+++f ++ +e+ +++++KWNFDF+nd PL Gry We+ FUN_000909-T1 36 NLFGPVDHEQLKADFLREKEEIIKEDTRKWNFDFENDIPLLGRYLWEK 83 8**********************************************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 673 (0.0263457); expected 510.9 (0.02) Passed bias filter: 445 (0.0174202); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1876.13 // Query: FUN_000910-T1 [L=434] Description: FUN_000910 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-58 196.0 0.2 2.4e-28 98.9 0.0 2.5 2 C2 C2 domain 0.00032 21.2 0.0 0.031 14.7 0.0 2.6 2 PI3K_C2 Phosphoinositide 3-kinase C2 ------ inclusion threshold ------ 0.017 15.6 0.1 0.046 14.2 0.1 1.7 1 TMEM52 Transmembrane 52 0.022 15.1 0.1 0.038 14.3 0.1 1.3 1 DUF2291 Predicted periplasmic lipoprotein (DUF2291 0.039 15.1 0.1 0.11 13.7 0.1 1.8 1 EphA2_TM Ephrin type-A receptor 2 transmembrane dom 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 OATP Organic Anion Transporter Polypeptide (OAT 0.14 12.7 0.1 0.38 11.3 0.0 1.7 2 UPF0242 Uncharacterised protein family (UPF0242) N 0.14 11.8 0.5 5.2 6.7 0.0 2.5 2 TRAP_alpha Translocon-associated protein (TRAP), alph 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 DUF8060 Domain of unknown function (DUF8060) 0.25 12.3 1.0 1.4 9.9 0.7 2.4 2 CR_prot_dom_plant Plant cysteine-rich protein domain 0.32 11.4 0.3 0.57 10.6 0.3 1.3 1 PsbJ PsbJ 5.6 7.8 9.9 0.5 11.2 3.6 2.0 2 FAM163 FAM163 family Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.9 0.0 1.1e-31 2.4e-28 2 103 .. 175 280 .. 174 281 .. 0.95 2 ! 94.8 0.1 2.1e-30 4.6e-27 1 103 [. 312 417 .. 312 418 .. 0.94 Alignments for each domain: == domain 1 score: 98.9 bits; conditional E-value: 1.1e-31 C2 2 kLevkvieaknLpkkdkkgksdpyvkvkl.kdgkqkkkTkvvkktlnPvWnetftf.evpe..leeevLeieVydkdrlskddflGeveiplseld 93 +L+v v+ea+++p+kd++g+sdpy++v l +d+k+k+ T+v++ktlnPv+netf+f ++p ++++L ie+yd+dr+s++d++Ge+++pl ++d FUN_000910-T1 175 TLTVGVMEAQDVPAKDFSGTSDPYARVMLlPDRKKKFDTRVHRKTLNPVFNETFVFkNLPYseITNRTLCIELYDFDRFSRHDIIGEAKLPLIDVD 270 89******************************************************76666999******************************99 PP C2 94 sgeeaegwye 103 + ++w+ FUN_000910-T1 271 LAGNVDEWRA 280 9999999986 PP == domain 2 score: 94.8 bits; conditional E-value: 2.1e-30 C2 1 gkLevkvieaknLpkkdkkgksdpyvkvkl...kdgkqkkkTkvvkktlnPvWnetftfevpe..leeevLeieVydkdrlskddflGeveiplse 91 gkL+v ++eak+L+++d +g sdpyvk++l +++ +kkkT v+k+tlnP++netf f+v+ e+++L i+V+d+dr+++ +++G++ ++ e FUN_000910-T1 312 GKLQVVILEAKDLKSMDVSGYSDPYVKISLiqeGRKLKKKKTTVKKRTLNPYFNETFSFQVAFenIEQTSLVISVLDYDRVGRSEVIGKCIVG--E 405 68*******************************99****************************999*************************86..5 PP C2 92 ldsgeeaegwye 103 l sg +++w++ FUN_000910-T1 406 LSSGPDKQHWID 417 557999999976 PP >> PI3K_C2 Phosphoinositide 3-kinase C2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.045 96 32 80 .. 220 268 .. 206 271 .. 0.83 2 ! 14.7 0.0 1.4e-05 0.031 3 74 .. 333 401 .. 331 404 .. 0.86 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.045 PI3K_C2 32 ksikwnewitl.pikisdLPrsarLvitiwevkgkkkseplGwvnlsLFd 80 ++++ne+ + + +s++++ + L+i +++ + ++ +G+++l+L d FUN_000910-T1 220 LNPVFNETFVFkNLPYSEITNRT-LCIELYDFDRFSRHDIIGEAKLPLID 268 67888988888459999999997.9**********************998 PP == domain 2 score: 14.7 bits; conditional E-value: 1.4e-05 PI3K_C2 3 eklyvecqlysggkqlalpvstklksfsfksikwnewitlpikisdLPrsarLvitiwevkgkkkseplGwv 74 ++ yv+++l +g++l + +t++k+ ++ +ne+ + ++++++ ++ Lvi+++++ + +se +G++ FUN_000910-T1 333 SDPYVKISLIQEGRKLKKK-KTTVKKRT-LNPYFNETFSFQVAFENI-EQTSLVISVLDYDRVGRSEVIGKC 401 5779*************55.55555554.6*****************.6899*************9999987 PP >> TMEM52 Transmembrane 52 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 2.1e-05 0.046 12 56 .. 78 125 .. 73 143 .. 0.79 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 2.1e-05 TMEM52 12 iwlvvviggllLl.CGlv..svCvRcCclkkqaaeeeaspepyevtvi 56 w+v ++g+l+Ll G+ + C R Cc kk++ e++a +e++++ + FUN_000910-T1 78 WWMVFAAGALVLLvAGICfyCLCYRKCCKKKKKDEKKAVKEKVDLKAV 125 488889988865527886337888*********999999998887665 PP >> DUF2291 Predicted periplasmic lipoprotein (DUF2291) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.1 1.8e-05 0.038 4 57 .. 98 151 .. 95 162 .. 0.88 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.8e-05 DUF2291 4 allllsgckivkldeaeaaaekaafdpkayvaeiWdkkllpaleekavdlaell 57 +l+ + ck +k de++a +ek +++++++a+ +++k++p+++e ++ +e+ FUN_000910-T1 98 CLCYRKCCKKKKKDEKKAVKEKVDLKAVQMLAASYQEKVQPSVDELDYNSDEFQ 151 66777889***********************************99999988875 PP >> EphA2_TM Ephrin type-A receptor 2 transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 5e-05 0.11 3 40 .. 81 120 .. 79 141 .. 0.64 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 5e-05 EphA2_TM 3 gavagglvllvvvvvvlivrr.rrkkrskaeqdy.eekee 40 + +ag+lvllv+ ++++ ++ +++k++k+++++ +++ FUN_000910-T1 81 VFAAGALVLLVAGICFYCLCYrKCCKKKKKDEKKaVKEKV 120 6678888888887777555552565555555555344443 PP >> OATP Organic Anion Transporter Polypeptide (OATP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 8e-05 0.17 214 257 .. 77 126 .. 56 157 .. 0.71 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 8e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......x RF OATP 214 aWWlgflilgllllltaiplfffPkelpgkekrkakkkkeees......e 257 WW+ f +l+ll++ i ++++ ++ k+k+k++kk+ +e+ + FUN_000910-T1 77 PWWMVFAAGALVLLVAGICFYCLCYRKCCKKKKKDEKKAVKEKvdlkavQ 126 5***********************99555555555555444433453330 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00018 0.38 26 82 .. 75 129 .. 71 160 .. 0.75 2 ? -2.8 0.0 3.7 7.9e+03 99 131 .. 346 378 .. 333 386 .. 0.66 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00018 UPF0242 26 llseqksWtllsiglllaaagslllllllkqwekalkekfeksfleekeallteed.a 82 l+ +W +++ g l+++++ ++ l + k+k ek+ ++ek l + + a FUN_000910-T1 75 RLP---WWMVFAAGALVLLVAGICFYCLCYRKCCKKKKKDEKKAVKEKVDLKAVQMlA 129 566...*******************999999888888888999999988765555443 PP == domain 2 score: -2.8 bits; conditional E-value: 3.7 UPF0242 99 eeeleeelsqkeeeleklkeekeqlklkleqis 131 + +++ k+ +l+ + +e ++++ e+i+ FUN_000910-T1 346 RKLKKKKTTVKKRTLNPYFNETFSFQVAFENIE 378 334445566667777777777777776666655 PP >> TRAP_alpha Translocon-associated protein (TRAP), alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.0024 5.2 130 171 .. 82 120 .. 78 125 .. 0.69 2 ? 2.4 0.1 0.05 1.1e+02 10 41 .. 354 385 .. 343 388 .. 0.80 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0024 TRAP_alpha 130 slevvLllliagvvyflyklvlkskkkkrkakkkkvetgkav 171 ++ L+ll+ag++++++ + k kkk+k +kk+v+++ v FUN_000910-T1 82 FAAGALVLLVAGICFYCLCYR-KCCKKKKKDEKKAVKEK--V 120 666789999999999998888.56566665555555443..4 PP == domain 2 score: 2.4 bits; conditional E-value: 0.05 TRAP_alpha 10 adlsevlefeagetitlnytftNkededvtvv 41 + ++ +l+ + +et+++++ f N e+++ ++ FUN_000910-T1 354 TVKKRTLNPYFNETFSFQVAFENIEQTSLVIS 385 456677888899**************999886 PP >> DUF8060 Domain of unknown function (DUF8060) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00016 0.35 9 77 .. 27 98 .. 15 102 .. 0.64 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00016 DUF8060 9 dtptadeadttadraadstaeaseatrdess...desreeresserlrrlldyaaLavlsllAvvaliqfYl 77 + +t ++++ +++++++++++++++++++ +++++e+++ ++ +rl +++ a+ l+ +va+i fY FUN_000910-T1 27 SAKTVKPQEIITSTTTTTKPTEPPTKASTTMptlKRETTEKPQPANPQRLPWWMVFAAGALVLLVAGICFYC 98 3344444444444444444444333333322224666788899999999999*******************6 PP >> CR_prot_dom_plant Plant cysteine-rich protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.7 0.00065 1.4 51 71 .] 86 110 .. 69 110 .. 0.73 2 ? -1.4 0.0 2.1 4.5e+03 18 40 .. 142 164 .. 137 167 .. 0.79 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00065 CR_prot_dom_plant 51 vvilLvialvslCfl....akkkkk 71 ++lLv ++ +C++ +kkkkk FUN_000910-T1 86 ALVLLVAGICFYCLCyrkcCKKKKK 110 3578888999999854443777776 PP == domain 2 score: -1.4 bits; conditional E-value: 2.1 CR_prot_dom_plant 18 rLvgesdtPisdeslsfklGkvt 40 L +sd sd s + k G+v FUN_000910-T1 142 ELDYNSDEFQSDGSAAVKIGRVH 164 5555889999**********985 PP >> PsbJ PsbJ # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.3 0.00027 0.57 5 29 .. 74 97 .. 71 99 .. 0.90 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00027 PsbJ 5 GRIPLWlVatvaGlgvitvvGiFfY 29 R P W+V +aG v+ v Gi fY FUN_000910-T1 74 QRLPWWMV-FAAGALVLLVAGICFY 97 599*9999.79*************9 PP >> FAM163 FAM163 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.3 0.63 1.3e+03 38 82 .. 16 56 .. 10 82 .. 0.42 2 ? 11.2 3.6 0.00024 0.5 14 67 .. 83 137 .. 79 163 .. 0.66 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.63 FAM163 38 deseeeeeeeeefavleplacnacsselvdgeaatangpselssa 82 +++e++++e++ ++++p+ + ++s++ +++ +++p++ s++ FUN_000910-T1 16 SDTEDNKREKPSAKTVKPQ--EIITSTTTTTKP--TEPPTKASTT 56 3444444555555444444..222222222111..2222222222 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00024 FAM163 14 atviLLciiavLCyCRLqY.YCCkkdeseeeeeeeeefavleplacnacsselvd 67 a+ L+ ++a +C+ L Y CCkk++++e+++ +e+++ + ++ a+ +e v+ FUN_000910-T1 83 AAGALVLLVAGICFYCLCYrKCCKKKKKDEKKAVKEKVDLKAVQMLAASYQEKVQ 137 666677778888865555637*******998888877766444444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (434 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1366 (0.0534743); expected 510.9 (0.02) Passed bias filter: 781 (0.0305735); expected 510.9 (0.02) Passed Vit filter: 108 (0.00422783); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4314.58 // Query: FUN_000911-T1 [L=373] Description: FUN_000911 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-33 114.5 1.4 2.1e-15 57.3 0.1 2.2 2 C2 C2 domain ------ inclusion threshold ------ 0.23 11.9 1.2 1 9.8 0.1 2.3 3 Protocadherin Protocadherin Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.3 0.1 1.6e-19 2.1e-15 3 94 .. 114 210 .. 112 221 .. 0.92 2 ! 56.4 0.1 3.1e-19 3.9e-15 2 103 .. 246 356 .. 245 357 .. 0.87 Alignments for each domain: == domain 1 score: 57.3 bits; conditional E-value: 1.6e-19 C2 3 LevkvieaknLpkkdkkgksdpyvkvkl...kdgkqkkkTkvvkktlnPvWnetftfevpe..leeevLeieVydkdrlskddflGeveiplseld 93 L +++iea++L kd+ ++d yvk +l +dg+ +++++vv+k+ nP++ e ++f+++ ++++L +++++ d++s++ ++Ge +++l++l FUN_000911-T1 114 LLLNIIEANQLVGKDFWDTVDSYVKTRLqpdNDGTFRRQSQVVRKSKNPRFTENYEFHLSFkeVQNSTLYLSLWEIDKYSRHYMIGELQMKLDQLI 209 7789**************************9999999******9999**********999999******************************944 PP C2 94 s 94 + FUN_000911-T1 210 K 210 3 PP == domain 2 score: 56.4 bits; conditional E-value: 3.1e-19 C2 2 kLevkvieaknLpkk....dk.kgksdpyvkvkl...kdgkqkkkTkvvkktlnPvWnetftfevpe..leeevLeieVydkdrl.skddflGeve 86 +++v +++a+nL++ d ++ ++p++kv l +++ +kkkT++ ++ nPv+ne ++f+vp+ l++ + i+V d+++ ++ +++G+v FUN_000911-T1 246 RMSVVLMKARNLNPPlsdwDTeSRPINPFIKVVLlfdGKKVKKKKTSTRRQENNPVYNECMMFDVPPdlLHRVLFVISVADSNTDsTRSNVIGRVV 341 67899*******5554555336888************99********9988878**************888888899****888549999****** PP C2 87 iplseldsgeeaegwye 103 i+ ++ ge+ ++w++ FUN_000911-T1 342 IGSAT--TGEPLRHWHQ 356 **999..9999999987 PP >> Protocadherin Protocadherin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.1 8e-05 1 42 76 .. 11 45 .. 6 106 .. 0.82 2 ? 0.5 0.0 0.059 7.5e+02 18 57 .. 79 118 .. 70 190 .. 0.85 3 ? -2.3 0.0 0.4 5.1e+03 97 115 .. 286 304 .. 282 346 .. 0.54 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 8e-05 Protocadherin 42 iavlaGvvtvilvilivvlvRycrqkaksgykagk 76 +++++G+++++++++i ++ + r k+k+ y+ + FUN_000911-T1 11 LGIVSGAIAILILMVICMVCKLSRLKEKPAYRDSS 45 79*******************99999*****9765 PP == domain 2 score: 0.5 bits; conditional E-value: 0.059 Protocadherin 18 tpldrdiagdpdvealakdrlkiliavlaGvvtvilvili 57 + ++ ++a++++v + k+r +i ++++ + + il++ i FUN_000911-T1 79 AKINDNVAQQTSVPSPPKNRGSIKFSMIYQSNVQILLLNI 118 5678899999999999999999999999888888877655 PP == domain 3 score: -2.3 bits; conditional E-value: 0.4 Protocadherin 97 kkkkkkkkpaklqksllln 115 kkkk+++ + ++ ++ + FUN_000911-T1 286 VKKKKTSTRRQENNPVYNE 304 3333333322333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (373 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 965 (0.0377765); expected 510.9 (0.02) Passed bias filter: 712 (0.0278724); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3676.85 // Query: FUN_000912-T1 [L=809] Description: FUN_000912 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-45 154.2 1.2 4.8e-23 81.9 0.1 2.8 2 BTB BTB/POZ domain 5.5e-32 109.4 0.9 1.7e-10 40.7 0.1 3.7 3 Kelch_1 Kelch motif 1.6e-17 64.0 0.0 3.4e-17 63.0 0.0 1.4 1 Kelch_KLHDC2_KLHL20_DRC7 KLHDC2/KLHL20/DRC7 Kelch-repeats do 2.5e-17 63.3 0.2 9.8e-17 61.4 0.1 1.8 2 Beta-prop_Calicin Calicin, beta-propeller domain 2.2e-16 60.8 0.6 7.4e-09 36.1 0.3 2.3 2 Kelch_FKB95 FKB95, Kelch-repeats domain 1.4e-15 57.7 3.1 1.9e-15 57.3 1.7 1.9 2 BACK BTB And C-terminal Kelch 2.3e-14 54.0 0.1 4.5e-14 53.1 0.1 1.4 1 Beta-prop_FBX42 FBX42, beta-propeller domain 7.7e-13 48.8 0.0 1.4e-12 48.0 0.0 1.3 1 Beta-prop_ATRN-LZTR1 Attractin/LZTR1 beta-propeller 4e-09 36.5 0.1 0.15 12.6 0.0 4.1 3 Kelch_2 Kelch motif 1.6e-08 34.3 0.4 2e-05 24.1 0.0 2.5 3 NANM N-acetylneuraminate epimerase 8.4e-05 22.8 0.0 0.0019 18.5 0.0 2.5 2 BTB_KLHL33 Kelch-like protein 33-like, BTB/POZ 0.001 19.5 0.0 0.025 15.0 0.0 2.0 2 Beta-prop_TYW4 tRNA wybutosine-synthesizing protei 0.0067 17.1 2.4 3.6 8.4 0.0 4.5 4 BTB_SANBR SANT and BTB domain regulator of CS ------ inclusion threshold ------ 0.016 16.5 0.1 0.038 15.2 0.1 1.6 1 RTTN_N Rotatin, an armadillo repeat protei 0.062 13.4 0.0 0.11 12.5 0.0 1.3 1 DUF6242_C DUF6242 beta propeller domain Domain annotation for each model (and alignments): >> BTB BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 81.9 0.1 2.8e-26 4.8e-23 1 107 [. 68 170 .. 68 173 .. 0.93 2 ! 70.5 0.1 9.7e-23 1.7e-19 8 109 .. 201 301 .. 194 302 .. 0.95 Alignments for each domain: == domain 1 score: 81.9 bits; conditional E-value: 2.8e-26 BTB 1 lnelrekgklcDvtlvvedgkkfkahkavLaacSpyFkalfsskeeeessvseieledvspedfealLefiYtgeleiseenveelLaladklqip 96 ln++r+++ ++D t+ v+ g f++hk vLaacS++F++lfs+ +s+++ e ++v++++++++L+++Ytg+++ ++ n+ ++L+lad l i+ FUN_000912-T1 68 LNQYRQENLFTDFTIRVN-GGDFPVHKNVLAACSNFFNDLFSGS---DSHSIDCEFDKVDVSIMDNMLNILYTGKCKTDQNNIVAMLSLADTLGIQ 159 7999**************.8***********************9...555566999**************************************** PP BTB 97 slvkkceeflk 107 +l k e ++ FUN_000912-T1 160 DLFSKFAENIE 170 **999888765 PP == domain 2 score: 70.5 bits; conditional E-value: 9.7e-23 BTB 8 gklcDvtlvvedgkkfkahkavLaacSpyFkalfsskeeeessvseieledvspedfealLefiYtgeleiseenveelLaladklqipslvkkce 103 g +cD+tl + gk +++hk vLa+ S yFk lf s+ ++e + +++ ++ ++e lL+f+Y ge++i+ +n+ +lL++ d+l i+ l++++ FUN_000912-T1 201 GLFCDLTLTMSSGKVVPVHKNVLASTSCYFKGLFRSE-MREVHERNVYFGVIDEAIVEDLLKFVYLGEINITFDNLRSLLQASDYLLIEPLKRQII 295 68***********************************.89999999************************************************** PP BTB 104 eflkks 109 +f+k++ FUN_000912-T1 296 DFIKEN 301 **9987 PP >> Kelch_1 Kelch motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.7 0.1 9.9e-14 1.7e-10 3 46 .] 538 583 .. 536 583 .. 0.96 2 ! 36.5 0.1 2.1e-12 3.5e-09 10 45 .. 595 633 .. 586 634 .. 0.92 3 ! 28.7 0.0 5.6e-10 9.6e-07 1 41 [. 636 677 .. 636 679 .. 0.95 Alignments for each domain: == domain 1 score: 40.7 bits; conditional E-value: 9.9e-14 Kelch_1 3 sgagvvvvggkiYviGGfdg..gqslnsvevYDpetntWsklpsmp 46 ++++v++g +iY iGG+ + +++v +YD+e+++Ws++++m+ FUN_000912-T1 538 FDCAAVTMGKYIYLIGGMSMqeRTEVKTVQRYDVEKQSWSSVADMR 583 689******************************************5 PP == domain 2 score: 36.5 bits; conditional E-value: 2.1e-12 Kelch_1 10 vggkiYviGGfdg...gqslnsvevYDpetntWsklpsm 45 + +i+v+GG dg +l++ve+YDp ++Ws+++sm FUN_000912-T1 595 KNKYIFVFGGIDGsshRECLKTVERYDPLVDRWSYVTSM 633 5789**********************************9 PP == domain 3 score: 28.7 bits; conditional E-value: 5.6e-10 Kelch_1 1 pRsgagvvvvggkiYviGGfdg.gqslnsvevYDpetntWsk 41 pRs a + v++++iYviGG +g + e YDp t++W FUN_000912-T1 636 PRSSAFAFVHNERIYVIGGERGeDVTPTDCELYDPLTDEWQV 677 79999999********************************86 PP >> Kelch_KLHDC2_KLHL20_DRC7 KLHDC2/KLHL20/DRC7 Kelch-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.0 0.0 2e-20 3.4e-17 3 155 .. 541 690 .. 530 702 .. 0.82 Alignments for each domain: == domain 1 score: 63.0 bits; conditional E-value: 2e-20 Kelch_KLHDC2_KLHL20_DRC7 3 tavavgnklyvfGGelkkdgsatndlyvldletlewsklevkgevpppryghsavvveegnklyvFGGrdee..gkrlndlyvld 85 +av++g+ +y++GG ++ + +++ +d+e+++ws + + +pry+ +av + +++ ++vFGG d++ +++l+ + +d FUN_000912-T1 541 AAVTMGKYIYLIGGMSMQERTEVKTVQRYDVEKQSWSSVA---DMREPRYELTAVNY-KNKYIFVFGGIDGSshRECLKTVERYD 621 6889999999999999888889999999999999999975...66789999999988.599999999998642268899999999 PP Kelch_KLHDC2_KLHL20_DRC7 86 lktltwskpstegtpPspreghsatvvgnklyvFGGrsgggrl.ndlwvldletltwsqlets.geapspre 155 +ws ++ +pr+++ a v+++++yv GG g++ + d +d+ t +w+ ++++ +++ +pr FUN_000912-T1 622 PLVDRWSYVTS---MHQPRSSAFAFVHNERIYVIGGERGEDVTpTDCELYDPLTDEWQVMRIQvNTRYTPRG 690 99999999975...5789999999999999999999998887669999999999999988776344455554 PP >> Beta-prop_Calicin Calicin, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.76 1.3e+03 267 293 .. 452 478 .. 442 484 .. 0.85 2 ! 61.4 0.1 5.7e-20 9.8e-17 45 189 .. 541 684 .. 532 701 .. 0.81 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.76 Beta-prop_Calicin 267 eytisedaclfnqelGkWknvaepPea 293 +yt s + c + + G W+ +a P FUN_000912-T1 452 HYTHSYNLCYWLPFAGPWSLIARIPHN 478 68889999**************99975 PP == domain 2 score: 61.4 bits; conditional E-value: 5.7e-20 Beta-prop_Calicin 45 satsvgkylyvsGGtseql.tslkvalrydldgnsWsklaelpiglvfltlvacdG.avytvGGsr..aprkyqqsieryderkekWttvgk 132 +a ++gky+y+ GG s q t +k+ ryd++ +sWs +a+++ ++ lt v+ + ++ GG + r +++eryd+ ++W+ v+ FUN_000912-T1 541 AAVTMGKYIYLIGGMSMQErTEVKTVQRYDVEKQSWSSVADMREPRYELTAVNYKNkYIFVFGGIDgsSHRECLKTVERYDPLVDRWSYVTS 632 6789**********998752779*****************************9886258999987522578999****************** PP Beta-prop_Calicin 133 lsvkmdnaeviskGdkyiyvvtGrcivkgiisrvgvvdcfdtsvgevtqvltiPikl 189 + ++ +a + + iyv+ G + + +d ++e++ v+ i ++ FUN_000912-T1 633 MHQPRSSAFAF-VHNERIYVIGGERGEDV---TPTDCELYDPLTDEWQ-VMRIQVNT 684 *****998766.55778****99754443...3444688999999995.56665554 PP >> Kelch_FKB95 FKB95, Kelch-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.1 0.3 4.4e-12 7.4e-09 25 124 .. 529 631 .. 509 632 .. 0.84 2 ! 30.4 0.1 2.4e-10 4.1e-07 48 126 .. 605 681 .. 605 692 .. 0.87 Alignments for each domain: == domain 1 score: 36.1 bits; conditional E-value: 4.4e-12 Kelch_FKB95 25 pipslpplplssslvavgseiYviggsine..kpsssvsilDcrshtwreapsmrvarks.asasvlDgkIYVaGgceeeesksssnwvevFDtkt 117 +i + p+ ++ v++g iY igg + + + ++v +D + + w + +mr +r++ +++++ ++ I+V+Gg + ++++ ++ve +D+ FUN_000912-T1 529 EIEPSAPMTFDCAAVTMGKYIYLIGGMSMQerTEVKTVQRYDVEKQSWSSVADMREPRYElTAVNYKNKYIFVFGGIDGSSHRECLKTVERYDPLV 624 4566778889999*************87551156799*********************883556888889********988888999********* PP Kelch_FKB95 118 qtWelvp 124 W+ v+ FUN_000912-T1 625 DRWSYVT 631 ***9876 PP == domain 2 score: 30.4 bits; conditional E-value: 2.4e-10 Kelch_FKB95 48 iggsinekpsssvsilDcrshtwreapsmrvarksasasvlDgkIYVaGgceeeesksssnwvevFDtktqtWelvpsp 126 i gs++++ ++v +D w + sm+ +r+sa a v +++IYV+Gg + e+ +++ e +D+ t W+++ ++ FUN_000912-T1 605 IDGSSHRECLKTVERYDPLVDRWSYVTSMHQPRSSAFAFVHNERIYVIGGERGEDV-TPTD-CELYDPLTDEWQVMRIQ 681 6778888899999999***********************************99885.4555.6***********87654 PP >> BACK BTB And C-terminal Kelch # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 3.6 6.1e+03 2 25 .. 147 170 .. 146 187 .. 0.80 2 ! 57.3 1.7 1.1e-18 1.9e-15 12 101 .. 319 407 .. 309 409 .. 0.95 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 3.6 BACK 2 lgilefAeaysceeLkeaakefil 25 +++l++A+++++++L ++ e i+ FUN_000912-T1 147 VAMLSLADTLGIQDLFSKFAENIE 170 578899999999999988777665 PP == domain 2 score: 57.3 bits; conditional E-value: 1.1e-18 BACK 12 sceeLkeaakefilknfeevlkseeFleLskeqllellssdeLnvesEeevfeavlkWlkhdveerkehlaelLsavRlpllspeylkel 101 +++e+++ + +f++++f ++++s+eFl ++ +++ +ls+d++ ++sE +++e +++W kh +e+rke + +lL+ ++++ ++ +ylk+l FUN_000912-T1 319 CLDEVYQEMVNFVCSHFWSIATSSEFLHITDQDVRWFLSNDDI-LSSEAQMLESLIRWYKHSEEDRKESFRRLLNLIHMSNIPDQYLKSL 407 5689999************************************.*******************************************975 PP >> Beta-prop_FBX42 FBX42, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.1 0.1 2.6e-17 4.5e-14 6 166 .. 540 690 .. 536 698 .. 0.84 Alignments for each domain: == domain 1 score: 53.1 bits; conditional E-value: 2.6e-17 Beta-prop_FBX42 6 acyvdskkslYvfGGctnssaktafnDlwrldlssrewtrplasgkyPspkagatlvaykdk.LilfGGwakpspyplhqskklfnelhiydie 98 +++v +k++Y++GG++ + + t ++ + r+d+++++w+ + + +p+++ t+v yk+k +++fGG+ +s ++++ + yd+ FUN_000912-T1 540 CAAVTMGKYIYLIGGMSMQ-ERTEVKTVQRYDVEKQSWSSVADM---REPRYELTAVNYKNKyIFVFGGIDGSS------HRECLKTVERYDPL 623 44555579********975.6899***************97655...5699********775399****97654......4689********** PP Beta-prop_FBX42 99 tnwwslvvtgkkpparagHsatvvgdkmvvfGGsngakqlsndvwvldletltwskpsis.gakPspRs 166 +ws v++ ++p r++ a+v++++++v+GG g+ d+ ++d t +w+ ++i+ +++ pR FUN_000912-T1 624 VDRWSYVTSMHQP--RSSAFAFVHNERIYVIGGERGEDVTPTDCELYDPLTDEWQVMRIQvNTRYTPRG 690 *******988776..66999******************999***************9998445666665 PP >> Beta-prop_ATRN-LZTR1 Attractin/LZTR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.0 0.0 7.9e-16 1.4e-12 100 254 .. 543 681 .. 522 704 .. 0.70 Alignments for each domain: == domain 1 score: 48.0 bits; conditional E-value: 7.9e-16 Beta-prop_ATRN-LZTR1 100 vtskegkevmlvifGyspkyg.ylnkvqeynletkeweivktkgalvkgryghssvydpetesiyVyGGyksesasssklsdelysydv 187 vt+ g +++++i+G s ++ +++vq+y++e+++w+ v + ry ++v + +++ i+V+GG+ + s ++ +++ +yd+ FUN_000912-T1 543 VTM--G-KYIYLIGGMSMQERtEVKTVQRYDVEKQSWSSVADMR---EPRYELTAVNY-KNKYIFVFGGIDGS--SHRECLKTVERYDP 622 333..2.3688888888765427888888888888888887654...66888888854.46888888888754..44578888888888 PP Beta-prop_ATRN-LZTR1 188 ekktWtllkssgsprflHsaviinglmlvfGGnthndtseskgakcyssdllvYdiecdkWsklkep 254 W+ ++s ++pr a + n+ ++v+GG+ +d +d +Yd d+W+ + + FUN_000912-T1 623 LVDRWSYVTSMHQPRSSAFAFVHNERIYVIGGERGEDV--------TPTDCELYDPLTDEWQVMRIQ 681 88888888888888888888888888888888866554........445666788888888766543 PP >> Kelch_2 Kelch motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.0 0.00043 0.73 4 47 .. 539 582 .. 537 583 .. 0.83 2 ! 12.6 0.0 8.6e-05 0.15 1 47 [. 585 633 .. 585 634 .. 0.90 3 ! 8.7 0.0 0.0016 2.6 2 41 .. 637 675 .. 636 678 .. 0.78 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00043 Kelch_2 4 phasvvpggklyvvGGstgngdess..sdvlvldpetnvWeelprl 47 ++a+v++g +y++GG + e + +v +d e+++W+ ++++ FUN_000912-T1 539 DCAAVTMGKYIYLIGGM--SMQERTevKTVQRYDVEKQSWSSVADM 582 689999999********..5555552278999***********988 PP == domain 2 score: 12.6 bits; conditional E-value: 8.6e-05 Kelch_2 1 pryphasvvpggk.lyvvGGs.tgngdesssdvlvldpetnvWeelprl 47 pry ++v+ ++k ++v+GG+ ++ + e + +v +dp ++W++++++ FUN_000912-T1 585 PRYELTAVNYKNKyIFVFGGIdGSSHRECLKTVERYDPLVDRWSYVTSM 633 677888887777769********************************98 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0016 Kelch_2 2 ryphasvvpggklyvvGGstgngdesssdvlvldpetnvW 41 r+ + v+++++yv+GG + d + d ++dp t++W FUN_000912-T1 637 RSSAFAFVHNERIYVIGGE-RGEDVTPTDCELYDPLTDEW 675 666777799**********.55555577888889999888 PP >> NANM N-acetylneuraminate epimerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 8e-06 0.014 57 130 .. 540 610 .. 531 621 .. 0.77 2 ! 24.1 0.0 1.2e-08 2e-05 39 125 .. 572 655 .. 569 661 .. 0.86 3 ! 9.2 0.0 0.00039 0.67 52 99 .. 635 678 .. 625 698 .. 0.65 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 8e-06 NANM 57 avaaavdgklYvFgGlgkteeaelqiindayrydpeenkWekl.etrsPvglvGasavtlkd.kivllGGvnkeif 130 +a++++ +Y+ gG+ +e++ +++++ryd e+++W+ + + r P+ + av++k+ i+++GG++ + + FUN_000912-T1 540 CAAVTMGKYIYLIGGMSMQERT---EVKTVQRYDVEKQSWSSVaDMREPRYELT--AVNYKNkYIFVFGGIDGSSH 610 567788889*******999887...578999**********9845799998875..56666636889999876655 PP == domain 2 score: 24.1 bits; conditional E-value: 1.2e-08 NANM 39 kdakWqeiaeFpggarsqavaaavdgklYvFgGlgkteeaelqiindayrydpeenkWeklet.rsPvglvGasavtlkdkivllGGv 125 +++ W ++a+ + + +++ + ++vFgG++ + + + ++++ rydp ++W+ ++ + P++ a a++++++i+++GG FUN_000912-T1 572 EKQSWSSVADMREPRYELTAVNYKNKYIFVFGGIDGSSHR--ECLKTVERYDPLVDRWSYVTSmHQPRS--SAFAFVHNERIYVIGGE 655 4678**********9999999999**********877655..89***************9965246766..588999**********6 PP == domain 3 score: 9.2 bits; conditional E-value: 0.00039 NANM 52 garsqavaaavdgklYvFgGlgkteeaelqiindayrydpeenkWekl 99 ++rs a a + ++++Yv gG ++ + +d ydp +++W+ + FUN_000912-T1 635 QPRSSAFAFVHNERIYVIGGERGEDVT----PTDCELYDPLTDEWQVM 678 567778888888888888886655554....56778888888888744 PP >> BTB_KLHL33 Kelch-like protein 33-like, BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.28 4.7e+02 20 56 .. 123 159 .. 111 164 .. 0.80 2 ! 18.5 0.0 1.1e-06 0.0019 1 50 [. 233 282 .. 233 290 .. 0.93 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.28 BTB_KLHL33 20 saseLeaLlsfaYsGtLtlgwdevfeiteaAlqyQvq 56 + s ++ +l+ Y+G+ ++ +++ + + A + +q FUN_000912-T1 123 DVSIMDNMLNILYTGKCKTDQNNIVAMLSLADTLGIQ 159 55667899**********9999999988888777666 PP == domain 2 score: 18.5 bits; conditional E-value: 1.1e-06 BTB_KLHL33 1 mftsGmrESqqeavaLrtlsaseLeaLlsfaYsGtLtlgwdevfeiteaA 50 +f s mrE ++ v +++ + +e Ll+f+Y G+++ ++d++ + +a+ FUN_000912-T1 233 LFRSEMREVHERNVYFGVIDEAIVEDLLKFVYLGEINITFDNLRSLLQAS 282 79999*************************************98888876 PP >> Beta-prop_TYW4 tRNA wybutosine-synthesizing protein 4, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 1.5e-05 0.025 16 80 .. 547 614 .. 532 641 .. 0.69 2 ? 2.7 0.0 0.083 1.4e+02 43 123 .. 626 717 .. 612 741 .. 0.54 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1.5e-05 Beta-prop_TYW4 16 gkvlLvGGRts.PskalsDcWlfkkksneWervddlpvplyRHsavrlgessvLvfgGktdss..svl 80 + + L+GG + ++ ++ + ++ ++++W++v d+ +p+y +av+ +++++ vfgG ss ++l FUN_000912-T1 547 KYIYLIGGMSMqERTEVKTVQRYDVEKQSWSSVADMREPRYELTAVNYKNKYIFVFGGIDGSShrECL 614 45677777654144567888889999********************************8765422333 PP == domain 2 score: 2.7 bits; conditional E-value: 0.083 Beta-prop_TYW4 43 eWervddlpvplyRHsavr.lgessvLvfgGktdss....svllydvekgvlk........evkpkdevfgaslvsaavaydseskegvilgGg 123 +W+ v+++ +p+ sa++ ++++++ v+gG+ ++ ++ lyd+ ++ ++ + +p+ ++ + s++ + ++ ++e + g +Gg FUN_000912-T1 626 RWSYVTSMHQPRS--SAFAfVHNERIYVIGGERGEDvtptDCELYDPLTDEWQvmriqvntRYTPRGQTDQGSFLYHPATENKEPSVGKSCAGG 717 6777777666643..5554245556777777665432111234666554444311111111233444444555555555555555555555555 PP >> BTB_SANBR SANT and BTB domain regulator of CSR, BTB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.2 3.4e+02 16 92 .. 89 161 .. 82 165 .. 0.72 2 ! 8.4 0.0 0.0021 3.6 18 93 .. 218 291 .. 208 295 .. 0.84 3 ? 1.6 0.1 0.28 4.8e+02 72 90 .. 330 348 .. 314 351 .. 0.77 4 ? 0.3 0.0 0.73 1.3e+03 12 44 .. 351 383 .. 348 399 .. 0.79 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.2 BTB_SANBR 16 flCardlLetemryfeelikvyiseakrleevdlrv.rCdvsifdWLmkyvkgkkrkltpenvvsillssefLkmdeL 92 f ++++L ++f++l + s+ + +d + + dvsi+d +++ + k k +++n+v++l ++ L +++L FUN_000912-T1 89 FPVHKNVLAACSNFFNDLFSG--SD---SHSIDCEFdKVDVSIMDNMLNILYTGKCKTDQNNIVAMLSLADTLGIQDL 161 556666666666666666666..22...2223333216899************99*********99988888888877 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0021 BTB_SANBR 18 CardlLetemryfeelikvyiseakrleevdlrvrCdvsifdWLmkyvkgkkrkltpenvvsillssefLkmdeLv 93 ++++L + yf+ l + ++e ++ +v v d +i + L+k+v + ++t +n s+l +s++L ++ L FUN_000912-T1 218 VHKNVLASTSCYFKGLFRSEMREVHER-NVYFGV-IDEAIVEDLLKFVYLGEINITFDNLRSLLQASDYLLIEPLK 291 57889999999*****99977766554.455555.7999*******************************998876 PP == domain 3 score: 1.6 bits; conditional E-value: 0.28 BTB_SANBR 72 ltpenvvsillssefLkmd 90 + + si+ ssefL+++ FUN_000912-T1 330 FVCSHFWSIATSSEFLHIT 348 55566679********987 PP == domain 4 score: 0.3 bits; conditional E-value: 0.73 BTB_SANBR 12 ekrdflCardlLetemryfeelikvyiseakrl 44 + r fl + d+L +e + +e li+ y + ++ FUN_000912-T1 351 DVRWFLSNDDILSSEAQMLESLIRWYKHSEEDR 383 67889999***************9987554433 PP >> RTTN_N Rotatin, an armadillo repeat protein, centriole functioning # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 2.2e-05 0.038 18 86 .. 355 424 .. 346 435 .. 0.87 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.2e-05 RTTN_N 18 liseedl.vkeklllkqLleWFnfeevpeeeevLeLlseLlkspsaaqvlrkigavefLsklrknlekel 86 ++s++d+ +e ++l +L++W+ + e ++e Ll+ + s+ +q+l+++ +++ + +l++ +l FUN_000912-T1 355 FLSNDDIlSSEAQMLESLIRWYKHSEEDRKESFRRLLNLIHMSNIPDQYLKSLAMEQGIDELSRFSGYKL 424 678899978999******************************************9999888887665555 PP >> DUF6242_C DUF6242 beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 6.4e-05 0.11 167 286 .. 548 657 .. 526 665 .. 0.84 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 6.4e-05 DUF6242_C 167 rlllvGgrdaagkl.ttsvWgkdeeaqpWaklssaaenkyllpaltnlsvikyde.allafG..egdekkkafstfYiSkdnGi.tWkkaskklkl 257 ++l+Gg + ++++ ++v ++d e+q+W++++ + p++ +l++++y++ +++fG g++ ++ ++t+ + +d + W ++ + FUN_000912-T1 548 YIYLIGGMSMQERTeVKTVQRYDVEKQSWSSVAD-----MREPRY-ELTAVNYKNkYIFVFGgiDGSSHRECLKTVER-YDPLVdRWSYVTS-MHQ 635 57899999999888799999999999********.....777999.7777777776899***9988888899999986.6666626999999.888 PP DUF6242_C 258 PkdfksrgtafavvvdkknyIwligggsg 286 P r++afa+v ++ I++igg+ g FUN_000912-T1 636 P-----RSSAFAFV--HNERIYVIGGERG 657 8.....89999999..899*******997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (809 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 892 (0.0349188); expected 510.9 (0.02) Passed bias filter: 729 (0.0285379); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.41u 0.42s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 7602.95 // Query: FUN_000913-T1 [L=311] Description: FUN_000913 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-11 43.0 0.0 1.5e-10 41.7 0.0 1.7 2 C2 C2 domain Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 0.51 1.3e+04 80 96 .. 84 100 .. 75 103 .. 0.69 2 ! 41.7 0.0 6e-15 1.5e-10 3 103 .. 196 301 .. 194 302 .. 0.89 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.51 C2 80 dflGeveiplseldsge 96 ++lG+++++ ++l++ge FUN_000913-T1 84 KVLGKARFSRNQLERGE 100 46777777777766655 PP == domain 2 score: 41.7 bits; conditional E-value: 6e-15 C2 3 LevkvieaknLpkkdkkgksdpyvkvkl.kdgkqkkkTkvv..kktlnPvWnetftfevpe..leeevLeieVydkdrlskddflGeveiplseld 93 +++ +++ak++ + ++ y++v+l kd+k + + ++ k t+ P+Wne++ f+ e e+ L+i++++ d++s +++G+v ++l+e + FUN_000913-T1 196 ITIGLVQAKGIICQTNIQTAFLYAVVQLcKDEKIVDQREIEkqKMTFGPQWNEELFFSSGEnpIETLALRIQLMELDSFSTSHLIGQVVLSLDEGE 291 78999******9998899999*******98888888888664466688*********888889999****************************** PP C2 94 sgeeaegwye 103 +e +++wy+ FUN_000913-T1 292 FNETHPKWYD 301 ********97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (311 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 3174.21 // Query: FUN_000914-T1 [L=343] Description: FUN_000914 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-27 97.5 0.0 1.8e-27 96.9 0.0 1.2 1 PROPPIN PROPPIN 3e-10 40.3 0.0 3.8e-08 33.4 0.0 3.0 3 Beta-prop_WDR5 WDR5 beta-propeller domain 5e-10 39.3 0.1 1.2e-09 38.0 0.1 1.9 1 Beta-prop_THOC3 THOC3 beta-propeller domain 6.1e-09 36.1 0.0 2.6e-05 24.2 0.0 2.0 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 2.8e-08 34.0 0.0 5.3e-07 29.8 0.0 2.7 3 Beta-prop_EML_2 Echinoderm microtubule-associated 2.7e-07 31.0 0.0 9.6e-07 29.2 0.0 1.9 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1.9e-06 28.7 7.2 0.1 13.7 0.1 4.6 4 WD40 WD domain, G-beta repeat 4.7e-06 26.3 0.0 2.4e-05 24.0 0.0 1.9 2 WDR55 WDR55 7.8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 WD40_Prp19 Prp19 WD40 domain 9.4e-06 25.5 0.1 0.00012 21.9 0.1 2.5 3 WD40_WDHD1_1st WDHD1 first WD40 domain 2.1e-05 24.1 0.1 3.8e-05 23.3 0.1 1.3 1 Beta-prop_VPS8 Vps8 beta-propeller 2.3e-05 23.6 0.1 7.7e-05 21.9 0.0 1.9 2 BCAS3_WD40 BCAS3, WD40 repeat 8.5e-05 22.6 0.0 0.00046 20.3 0.0 2.0 3 Beta-prop_EML Echinoderm microtubule-associated 0.00044 20.1 0.1 0.0021 17.8 0.0 2.1 2 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 0.00056 19.9 0.0 0.00093 19.2 0.0 1.4 1 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 0.00065 19.5 0.4 0.059 13.1 0.0 2.7 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 0.0012 18.5 0.0 0.66 9.5 0.0 2.4 2 Beta-prop_IFT140_2nd IFT140 second beta-propeller 0.0013 18.3 0.0 0.002 17.7 0.0 1.2 1 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.0029 17.4 0.2 0.14 11.9 0.1 2.3 2 Beta-prop_Vps41 Vps42 beta-propeller 0.0029 17.1 0.0 0.0065 16.0 0.0 1.5 2 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 0.003 17.4 0.1 1.5 8.5 0.0 2.3 2 KNTC1_N KNTC1, N-terminal 0.0031 18.2 0.0 3 8.6 0.0 2.5 2 ANAPC4_WD40 Anaphase-promoting complex subunit 0.0033 17.4 0.0 0.024 14.6 0.0 2.2 2 Beta-prop_IFT122_2nd IFT122 second beta-propeller 0.0073 16.0 0.0 0.41 10.2 0.0 2.8 3 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal ------ inclusion threshold ------ 0.012 15.3 0.0 0.056 13.1 0.0 2.0 2 Beta-prop_HPS5 HPS5 beta-propeller 0.012 14.8 0.0 0.091 12.0 0.0 2.0 2 Beta-prop_WDR41 WDR41 0.018 14.8 0.0 0.05 13.4 0.0 1.6 2 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 0.03 13.9 0.0 0.049 13.2 0.0 1.4 1 EIF3I EIF3I 0.061 12.9 0.0 0.17 11.5 0.0 1.8 2 Beta-prop_Aladin Aladin seven-bladed propeller 0.095 12.3 0.1 0.2 11.2 0.1 1.5 1 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 0.095 11.9 0.0 0.22 10.7 0.0 1.6 2 Beta-prop_IFT140_1st IFT140 first beta-propeller 0.19 11.0 0.1 10 5.3 0.0 2.1 2 NBCH_WD40 Neurobeachin beta propeller domain 0.24 11.0 0.0 9.7 5.7 0.0 2.3 2 Beta-prop_NWD2_C NWD2 C-terminal beta-propeller Domain annotation for each model (and alignments): >> PROPPIN PROPPIN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.9 0.0 2.3e-30 1.8e-27 6 251 .. 11 263 .. 7 283 .. 0.79 Alignments for each domain: == domain 1 score: 96.9 bits; conditional E-value: 2.3e-30 PROPPIN 6 sfnqdctslatgtkagyklfslssveqldqvhg..sneipdvyiverlfssslvvvvshtkprqmnvyhfkkgte..icnysyssnilsirlnrqr 97 fnqd ++ g++++ + + + +v +i + +++ r ++v +k + +vy + + + + s+ ++s+++ r++ FUN_000914-T1 11 DFNQDQGCFSCTMEGGFRIYNVEPLSEKARVDLnePCQISQTHMMHRCNLVAIVGTGPGAKFFNDKVYIWDDVLKelVMELSFGCPVMSVKMRRDK 106 799**999999999****999988888777753003345555555555444444444556777778999987543237899*************** PP PROPPIN 98 llvcleesiyihni.kdmkllktlldipanptglcalsinhsnsylayp....gsltsgeivlydgnslktvctiaahegtlaaitfnasgsklas 188 l+v ++ i + +d kll +d np glc + + +p gs+ ++ + ++ t ti ah+g la++++n g+++a+ FUN_000914-T1 107 LFVIFKTRIQVFSFpQDPKLL-FYFDTRENPKGLCVVCPSTERPLMVFPsqkcGSMQLVDLTNRQPDTSTTPSTINAHQGELACLAINQQGTQVAT 201 ***********9983566766.689**************9999999999222233333333334456677899*********************** PP PROPPIN 189 asekgtvirvfsvpdgqklyefrrgmkryvtisslvfsmdsqflcassntetvhifkleqvtn 251 asekgt+irvf + l e+rrg t+ + fs ds flc ss+ tvh+f l++ + FUN_000914-T1 202 ASEKGTLIRVFDTQTKNMLIELRRGADP-ATLYCINFSHDSAFLCVSSDKGTVHVFALKNTSL 263 *************************875.799*************************987643 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.15 1.2e+02 134 162 .. 6 33 .. 2 60 .. 0.86 2 ? 0.5 0.0 0.52 4e+02 242 271 .. 75 103 .. 68 114 .. 0.71 3 ! 33.4 0.0 5e-11 3.8e-08 123 211 .. 175 265 .. 164 307 .. 0.81 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.15 Beta-prop_WDR5 134 pvsavdfnrdgtlivsssyDgliriwdte 162 v +dfn+d + s+ ++g ri+++e FUN_000914-T1 6 DVFHIDFNQDQGC-FSCTMEGGFRIYNVE 33 688999**99776.69**********986 PP == domain 2 score: 0.5 bits; conditional E-value: 0.52 Beta-prop_WDR5 242 gkvyiwdlqskeivqkleghkdvvlavdch 271 +kvyiwd ke+v +l+ v++v++ FUN_000914-T1 75 DKVYIWDDVLKELVMELSF-GCPVMSVKMR 103 6889999888888888864.3456666555 PP == domain 3 score: 33.4 bits; conditional E-value: 5e-11 Beta-prop_WDR5 123 kclktlpaHsdpvsavdfnrdgtlivsssyDg.liriwdtetgqclktlveddnp.pvsfvkFspngkyiLastldstirLwdyekekvvk 211 ++ t++aH+ ++++n++gt ++++s g lir++dt+t ++l l + ++p + +++Fs ++ ++ +s+ t++++ ++++ + k FUN_000914-T1 175 TTPSTINAHQGELACLAINQQGTQVATASEKGtLIRVFDTQTKNMLIELRRGADPaTLYCINFSHDSAFLCVSSDKGTVHVFALKNTSLNK 265 5557888888888888888888888888887646888888888888888876444377888888888888888888888888887766554 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 0.1 1.6e-12 1.2e-09 150 245 .. 158 261 .. 3 273 .. 0.87 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 1.6e-12 Beta-prop_THOC3 150 dgtvevlsy....p.sleevktlkahtsnclcvafdpkgrylAvGsaD.alvslWDleeliclrtltrlesp..vrsvsFShdGkllAsasedk 235 g+++++++ p + ++ t++ah+++ c+a++++g+ +A++s+ +l++++D+++ +l l+r p +++FShd+++l+++s++ FUN_000914-T1 158 CGSMQLVDLtnrqPdTSTTPSTINAHQGELACLAINQQGTQVATASEKgTLIRVFDTQTKNMLIELRRGADPatLYCINFSHDSAFLCVSSDKG 251 4566666552222213345579************************75278*********99999999988844679***************** PP Beta-prop_THOC3 236 tidiasvetg 245 t+ ++++++ FUN_000914-T1 252 TVHVFALKNT 261 ****998875 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 3.7e-06 0.0028 28 170 .. 74 220 .. 58 228 .. 0.71 2 ! 24.2 0.0 3.4e-08 2.6e-05 69 168 .. 155 262 .. 124 273 .. 0.77 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 3.7e-06 WD40_CDC20-Fz 28 gssvylwnaetgevkelldlseesdyvtsvkwsedgelLavGtssgevelwdvekkkkl.rtleghssr....vgalawnenl.lssGsrdgkilh 117 +++vy+w+ +e +++ls + v+svk d+ ++++ t ++++++ + kl ++++++ v + + ++ l ++ ++ g+++ FUN_000914-T1 74 NDKVYIWDDVLKEL--VMELS-FGCPVMSVKMRRDKLFVIFKT---RIQVFSFPQDPKLlFYFDTRENPkglcVVCPSTERPLmVFPSQKCGSMQL 163 789****9886664..46666.4799*****999887776655...79999988776551444443322223355555555542566777899999 PP WD40_CDC20-Fz 118 hDvrtke...levvktlkahkqevcglkwspdgrllAsGgndnt.vkiwdlrslspl 170 D+ ++ +++ +t++ah++e l+++++g+++A+ ++++t ++++d+++ + l FUN_000914-T1 164 VDLTNRQpdtSTTPSTINAHQGELACLAINQQGTQVATASEKGTlIRVFDTQTKNML 220 99977642235556799**********************998762678888776655 PP == domain 2 score: 24.2 bits; conditional E-value: 3.4e-08 WD40_CDC20-Fz 69 Gtssgevelwdvekkk.....klrtleghssrvgalawnenl..lssGsrdgk.ilhhDvrtkelevvktlkahkqevcglkwspdgrllAsGgnd 156 ++ g+++l+d ++++ + +t+++h+ + ++la n++ +++ s++g+ i+++D++tk++ ++ + a +++s+d+ +l++++ + FUN_000914-T1 155 SQKCGSMQLVDLTNRQpdtstTPSTINAHQGELACLAINQQGtqVATASEKGTlIRVFDTQTKNMLIELRRGADPATLYCINFSHDSAFLCVSSDK 250 6788999999988776322214467899**********9875457777777763689********99999999*********************** PP WD40_CDC20-Fz 157 ntvkiwdlrsls 168 +tv+++ l+++s FUN_000914-T1 251 GTVHVFALKNTS 262 ******998765 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2.2 1.7e+03 128 142 .. 8 22 .. 3 67 .. 0.55 2 ? 0.1 0.0 0.75 5.8e+02 21 55 .. 76 110 .. 73 130 .. 0.87 3 ! 29.8 0.0 6.8e-10 5.3e-07 38 119 .. 183 268 .. 162 275 .. 0.82 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.2 Beta-prop_EML_2 128 thlDwsedskylqsn 142 h+D+ +d + ++ FUN_000914-T1 8 FHIDFNQDQGCFSCT 22 555555554443333 PP == domain 2 score: 0.1 bits; conditional E-value: 0.75 Beta-prop_EML_2 21 tvrlWdlekkklvakvklekearsvafspdgklla 55 v++Wd k+lv++++++ ++ sv++ d+ +++ FUN_000914-T1 76 KVYIWDDVLKELVMELSFGCPVMSVKMRRDKLFVI 110 699***99*****************9998876665 PP == domain 3 score: 29.8 bits; conditional E-value: 6.8e-10 Beta-prop_EML_2 38 lekearsvafspdgkllavGlkdGsvl.vldaetleevvevkd..rkeaisdikfspdgklLavgshdnkiylYdvsk.kykkvgk 119 + e+ ++a++++g+++a ++++G+++ v+d++t + ++e++ + + +i+fs+d+++L+v+s ++++++++++ +++k+++ FUN_000914-T1 183 HQGELACLAINQQGTQVATASEKGTLIrVFDTQTKNMLIELRRgaDPATLYCINFSHDSAFLCVSSDKGTVHVFALKNtSLNKRSS 268 466899******************976488999999999988832456889************************98734555555 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 5 3.9e+03 9 25 .. 75 91 .. 73 106 .. 0.72 2 ! 29.2 0.0 1.2e-09 9.6e-07 59 145 .. 172 261 .. 137 271 .. 0.83 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 5 Beta-prop_WDR3_1st 9 ekvlvWdlkkgekvatl 25 +kv++Wd +e v++l FUN_000914-T1 75 DKVYIWDDVLKELVMEL 91 57777777776666665 PP == domain 2 score: 29.2 bits; conditional E-value: 1.2e-09 Beta-prop_WDR3_1st 59 esgelevtfngHksavtalafdkdgsrLasGskD.tdiivwDvvaeaglfrLkgHkdqvt..svafleekkvlvssSkDtliklWdletq 145 +++++ t+n+H+++ +la +++g+++a++s+ t i v+D+ +++ l+ L+ d+ t + f++++ +l sS+ ++ ++ l++ FUN_000914-T1 172 DTSTTPSTINAHQGELACLAINQQGTQVATASEKgTLIRVFDTQTKNMLIELRRGADPATlyCINFSHDSAFLCVSSDKGTVHVFALKNT 261 456778999********************9996526788*************97777655227889999999999999999999999876 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.42 3.2e+02 12 39 .] 5 31 .. 2 31 .. 0.87 2 ! 12.6 0.0 0.0003 0.23 5 35 .. 178 208 .. 174 213 .. 0.88 3 ! 13.7 0.1 0.00014 0.1 14 38 .. 232 256 .. 222 256 .. 0.89 4 ? -0.1 0.1 3.2 2.5e+03 18 34 .. 298 314 .. 295 325 .. 0.65 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.42 WD40 12 sgVtslafspdgsllasgsdDgtvklWd 39 ++V ++f++d + s+ + g ++++ FUN_000914-T1 5 NDVFHIDFNQDQGCF-SCTMEGGFRIYN 31 56999*********8.999999999986 PP == domain 2 score: 12.6 bits; conditional E-value: 0.0003 WD40 5 rtlkgHtsgVtslafspdgsllasgsdDgtv 35 t+++H++ +la+++ g+ +a++s+ gt+ FUN_000914-T1 178 STINAHQGELACLAINQQGTQVATASEKGTL 208 6899**888*****************87775 PP == domain 3 score: 13.7 bits; conditional E-value: 0.00014 WD40 14 VtslafspdgsllasgsdDgtvklW 38 +++ fs+d+ +l+++sd gtv+++ FUN_000914-T1 232 LYCINFSHDSAFLCVSSDKGTVHVF 256 79********************986 PP == domain 4 score: -0.1 bits; conditional E-value: 3.2 WD40 18 a.fspdgsllasgsdDgt 34 + f + +s +a++ Dgt FUN_000914-T1 298 CaFGSGSSVVAVCV-DGT 314 42555555555544.877 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.97 7.5e+02 236 292 .. 18 74 .. 9 77 .. 0.85 2 ! 24.0 0.0 3.1e-08 2.4e-05 75 178 .. 159 270 .. 145 279 .. 0.79 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.97 WDR55 236 vvtgseDGiiRavhllPnrvlgvvGqheelpvekldiskdgkllassshdqkvkFwn 292 + ++++G R++++ P + v e ++ + ++ + +l+a +++ kF+n FUN_000914-T1 18 CFSCTMEGGFRIYNVEPLSEKARVDLNEPCQISQTHMMHRCNLVAIVGTGPGAKFFN 74 556778999999999999999999999999999999999999999999988888887 PP == domain 2 score: 24.0 bits; conditional E-value: 3.1e-08 WDR55 75 ksiavldvetgklkkki....ekahespiysllvide.nllatGdddGt.vklWDlRkkkavmelkehed..yisdlvvdeekklLlatsgdGtlt 162 s++++d+++++ + +ah+ + +l++ ++ + +at+ ++Gt ++++D+ +k++++el++ d + ++ +++++ +L+++s Gt+ FUN_000914-T1 159 GSMQLVDLTNRQPDTSTtpstINAHQGELACLAINQQgTQVATASEKGTlIRVFDTQTKNMLIELRRGADpaTLYCINFSHDSAFLCVSSDKGTVH 254 57778887776654433222268999999999987762468999999974699*************9999555678888999999*********** PP WDR55 163 vfnirkkklevqseey 178 vf +++ +l+ s FUN_000914-T1 255 VFALKNTSLNKRSSLA 270 *****99999988765 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 1.9e-08 1.5e-05 81 167 .. 174 261 .. 151 273 .. 0.65 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 1.9e-08 WD40_Prp19 81 ketaatlkkhkaevtslsvhptgdylvsaskDgt.walhdletgktllkvkdeeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksq 167 ++t +t+++h++e +l+++ g+ +++as+ gt + + d +t++ l +++ ++ +++++++f D +l + +++gtv+++ +k+ FUN_000914-T1 174 STTPSTINAHQGELACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRRGADPATLYCINFSHDSAFLCVSSDKGTVHVFALKNT 261 3444667777777777777777777777776665245667777777777776666667777777777777777777777777766654 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 4 3.1e+03 22 159 .. 20 34 .. 5 58 .. 0.49 2 ? -0.2 0.0 0.82 6.3e+02 28 75 .. 76 122 .. 73 135 .. 0.84 3 ! 21.9 0.1 1.5e-07 0.00012 85 165 .. 183 266 .. 137 274 .. 0.75 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 4 WD40_WDHD1_1st 22 TcGsDgdvriwegledddpksikvgekataiavksdklvvatddntvqlytfpegekdgiltrftapvthialskdgkllaagseDftikvvsve 116 +c + FUN_000914-T1 20 SCTME------------------------------------------------------------------------------------------ 24 33333.......................................................................................... PP WD40_WDHD1_1st 117 dsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdies 159 G +i+++e FUN_000914-T1 25 ---------------------------------GGFRIYNVEP 34 .................................3333333333 PP == domain 2 score: -0.2 bits; conditional E-value: 0.82 WD40_WDHD1_1st 28 dvriwegledddpksikvgekataiavksdklvvatddntvqlytfpe 75 +v iw+++ + ++++g ++++ + dkl+v + +q+++fp+ FUN_000914-T1 76 KVYIWDDVLKELVMELSFGCPVMSVKMRRDKLFVIF-KTRIQVFSFPQ 122 788999999888999999999999999999999986.56789999985 PP == domain 3 score: 21.9 bits; conditional E-value: 1.5e-07 WD40_WDHD1_1st 85 ftapvthialskdgkllaagseD.ftikvvsvedsskqktleghkap..vlsvaldpkgeylaSsscDGtvkiWdieskecvkt 165 + + ++a++++g+ +a +se + i+v ++++++ +l+ +p +++++ + +l ss Gtv+++ +++++ k FUN_000914-T1 183 HQGELACLAINQQGTQVATASEKgTLIRVFDTQTKNMLIELRRGADPatLYCINFSHDSAFLCVSSDKGTVHVFALKNTSLNKR 266 3456789999*****999999862569999999999889998554441156899999999**999999*****99999877665 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.1 4.9e-08 3.8e-05 60 144 .. 178 262 .. 172 278 .. 0.86 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 4.9e-08 Beta-prop_VPS8 60 takgaeqgaVsalafnadstrllaGyarGq.ilmwDlsngkllrtisdahppgtavlhikFtddptlalvsDsgGsvFelsfkrkl 144 ++ a+qg +la+n+++t++++ ++G+ i+++D+++ ++l ++ p + i+F +d+ + vs ++G v +k + FUN_000914-T1 178 STINAHQGELACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRRGADPA-TLYCINFSHDSAFLCVSSDKGTVHVFALKNTS 262 556789***********************7489**************999997.6889*********9999999999888887663 PP >> BCAS3_WD40 BCAS3, WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.2 9.2e+02 116 152 .. 83 119 .. 50 138 .. 0.76 2 ! 21.9 0.0 1e-07 7.7e-05 280 378 .. 170 259 .. 142 267 .. 0.87 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.2 BCAS3_WD40 116 rtgemvksiqfktpiydlhcnkrilvvvlqekiaafd 152 e+v + f p+ ++ + l v+++ +i f FUN_000914-T1 83 VLKELVMELSFGCPVMSVKMRRDKLFVIFKTRIQVFS 119 457899999999*****99999999999999999886 PP == domain 2 score: 21.9 bits; conditional E-value: 1e-07 BCAS3_WD40 280 dsdsdgivahfpahekpvccmafntsgmllvttdtlghdfhvfqilthpwsssqcavhhlytlhrgeteakvqdicfshdcrwvvvstlrgtshvf 375 + d+ + + ah+ ++c+a+n g + t+ g ++vf+ t+ l l+rg a + i fshd ++ vs+ +gt hvf FUN_000914-T1 170 QPDTSTTPSTINAHQGELACLAINQQGTQVATASEKGTLIRVFDTQTKN---------MLIELRRGADPATLYCINFSHDSAFLCVSSDKGTVHVF 256 556666667889*******************************987764.........6899********************************** PP BCAS3_WD40 376 pin 378 ++ FUN_000914-T1 257 ALK 259 975 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 2.6 2e+03 160 208 .. 8 56 .. 3 109 .. 0.59 2 ? -1.6 0.0 2.7 2.1e+03 179 249 .. 77 144 .. 63 158 .. 0.60 3 ! 20.3 0.0 5.9e-07 0.00046 7 97 .. 182 262 .. 181 276 .. 0.79 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.6 Beta-prop_EML 160 lclafsengdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlk 208 ++f+++ +++++ +G +++ + + + v ++++ ++++ FUN_000914-T1 8 FHIDFNQDQGCFSCTMEGGFRIYNVEPLSEKARVDLNEPCQISQTHMMH 56 5567777777777777777777765543333333333334444433333 PP == domain 2 score: -1.6 bits; conditional E-value: 2.7 Beta-prop_EML 179 ilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivawdanleklketelpesaggvraive 249 +++W++ ++++ +++ +v+s+++ +d+ ++ + +++ ++ ++ + l ++ +e+ +g++++++ FUN_000914-T1 77 VYIWDDVLKELVMELS--FGCPVMSVKMRRDKLFVIF-KTRIQVFSFPQDPKLLFYFDTRENPKGLCVVCP 144 5666655555544433..5567777777777776665.445566665555555555555555555555555 PP == domain 3 score: 20.3 bits; conditional E-value: 5.9e-07 Beta-prop_EML 7 gHtddikclavhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaa.vdesnehvlsvWdwq 97 H+ + cla++++++ vat+ +g ir+ d++t ++l l g + c++Fs+ d+ ++L++ d+ + hv + + + FUN_000914-T1 182 AHQGELACLAINQQGTQVATASEKG---------TLIRVFDTQTKNMLIELRRGADPATLYCINFSH-DS-AFLCVsSDKGTVHVFALKNTS 262 59999***************88765.........58******************************6.43.455540556666776665544 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 2.7e-06 0.0021 2 71 .. 192 264 .. 191 279 .. 0.80 2 ? -1.2 0.0 1.7 1.3e+03 28 52 .. 284 308 .. 276 315 .. 0.78 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 2.7e-06 Beta-prop_WDR90_POC16_2nd 2 vdksrrqlatvseDet.iriWdldtlqqlydfsasee..aPcavafhPskqvfacGfssGvvrvfsveatsll 71 ++++ q+at+se t ir++d++t + l ++ ++ + ++ f + + +++G+v+vf +++tsl FUN_000914-T1 192 INQQGTQVATASEKGTlIRVFDTQTKNMLIELRRGADpaTLYCINFSHDSAFLCVSSDKGTVHVFALKNTSLN 264 67888999****9988689************9866551144578888777777777889********999985 PP == domain 2 score: -1.2 bits; conditional E-value: 1.7 Beta-prop_WDR90_POC16_2nd 28 qlydfsaseeaPcavafhPskqvfa 52 l +f+ ++e Pc af ++v+a FUN_000914-T1 284 GLANFTVPAERPCICAFGSGSSVVA 308 5778999*******99987666655 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 1.2e-06 0.00093 48 228 .. 77 264 .. 21 276 .. 0.65 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 1.2e-06 Beta-prop_WDR36-Utp21_1st 48 ivvfkrgkevaellkeheekikkllvfgdhlvavdednsllvwkiete.elyteiefseeefeitallhpsTYlnKilvgskq. 129 ++++ + ++ + ++ ++ + d l+++ + ++++v++ ++ +l ++ e+ + +++ psT +++ s++ FUN_000914-T1 77 VYIWDDVLKELVMELSFGCPVMSVKMRRDKLFVIFK-TRIQVFSFPQDpKLLFYFDTR-ENPKGLCVVCPSTERPLMVFPSQKc 158 444444444333333444555555555555555554.445555555542333333333.3666778888888777777766544 PP Beta-prop_WDR36-Utp21_1st 130 GslqlwNirtgkliytfksfk.....saitaleqspaldvvaiglasGe.ivlhnikkdetllklkqeeg..pvtsisFrtDge 205 Gs+ql+++ +++ ++++++ ++ +l+ va + ++G+ i +++ ++ + l++l+ ++ + +i F +D + FUN_000914-T1 159 GSMQLVDLTNRQPDTSTTPSTinahqGELACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRRGADpaTLYCINFSHD-S 241 9******98877666664333334449*********************8456**************9755226779999999.6 PP Beta-prop_WDR36-Utp21_1st 206 pvlatgsssGdialwdLekrrlv 228 ++l+++s++G++ ++ L++ +l FUN_000914-T1 242 AFLCVSSDKGTVHVFALKNTSLN 264 7*****************98765 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2 1.5e+03 93 147 .. 16 72 .. 4 112 .. 0.57 2 ! 13.1 0.0 7.6e-05 0.059 253 288 .. 178 214 .. 171 220 .. 0.83 3 ! 12.2 0.1 0.00014 0.11 3 72 .. 188 263 .. 186 273 .. 0.83 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2 Beta-prop_WDR3_2nd 93 kglvtggaDkkvkfwefelveeees..kakklslkhtrtlklsddvlcvkvspdkkl 147 +g+++++ + +++++e ++e+ + ++ ++++t+ ++ + v v ++p +k+ FUN_000914-T1 16 QGCFSCTMEGGFRIYNVEPLSEKARvdLNEPCQISQTHMMHRCNLVAIVGTGPGAKF 72 566667777777777776665543311345556666666655555555555555555 PP == domain 2 score: 13.1 bits; conditional E-value: 7.6e-05 Beta-prop_WDR3_2nd 253 qtleghagevwalavsskgkfvvsashD.ksiRlwer 288 t+++h+ge+ +la+ ++g+ v++as+ iR+++ FUN_000914-T1 178 STINAHQGELACLAINQQGTQVATASEKgTLIRVFDT 214 5899*********************986256899964 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00014 Beta-prop_WDR3_2nd 3 Ravalssddklllsasse..svkiwnvkslecirtie..s..eyalclafvpgdrhvlvgtkdGklevldlasael 72 ++a++++ +++++as++ ++++++++++++ ++ + c+ f + +++ v++++G+++v+ l++++l FUN_000914-T1 188 ACLAINQQGTQVATASEKgtLIRVFDTQTKNMLIELRrgAdpATLYCINFSHDSAFLCVSSDKGTVHVFALKNTSL 263 589999*********9985579***********999733211456799999999999*************998765 PP >> Beta-prop_IFT140_2nd IFT140 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.0 0.00086 0.66 50 175 .. 77 204 .. 70 221 .. 0.79 2 ! 6.4 0.0 0.0074 5.7 117 136 .. 241 260 .. 228 273 .. 0.82 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00086 Beta-prop_IFT140_2nd 50 vvvYelsgsalksvgsfscesevvaiheqnvytvepnkvqvrtfQGtvkqllsfseaEGepvlldvn....gsfLvvgtdn.gvikifD 133 v++++ ++l + sf c +++v + ++++++ + ++qv +f k l+ f E l v+ + +v +++ g +++ D FUN_000914-T1 77 VYIWDDVLKELVMELSFGCPVMSVKMRRDKLFVIFKTRIQVFSFPQDPKLLFYFDTRENPKGLCVVCpsteRPLMVFPSQKcGSMQLVD 165 5555544467777889****************************999******9999976655555522213456655554489***** PP Beta-prop_IFT140_2nd 134 lsrReakqhsnsknlseaipdfgeiisvkcNsnGnkvsilva 175 l++R +++ ++ + ge++++ +N++G++v+ + FUN_000914-T1 166 LTNRQPDTSTTPSTINA---HQGELACLAINQQGTQVATASE 204 **********9999965...468999***********97655 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0074 Beta-prop_IFT140_2nd 117 gsfLvvgtdngvikifDlsr 136 + fL+v++d+g++++f l + FUN_000914-T1 241 SAFLCVSSDKGTVHVFALKN 260 68**************9976 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 2.6e-06 0.002 16 110 .. 158 258 .. 156 271 .. 0.79 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 2.6e-06 Beta-prop_WDR19_1st 16 agknkvvkiydrqGelvde...ikl.kgkctaleWdkdgdlLaiiqeksslvllwdantkkt.skldtgl.kdkltfllWskkspiLavG 99 +g+ ++v + +rq ++ + i+ +g+ + l+ +++g +a +ek +l+ ++d++tk++ +l g+ +l ++ s++s +L v FUN_000914-T1 158 CGSMQLVDLTNRQPDTSTTpstINAhQGELACLAINQQGTQVATASEKGTLIRVFDTQTKNMlIELRRGAdPATLYCINFSHDSAFLCVS 247 577788888888877766533344336899999999********************9998873578887755678999************ PP Beta-prop_WDR19_1st 100 tskGnlllYnk 110 ++kG++ ++ FUN_000914-T1 248 SDKGTVHVFAL 258 ****9988754 PP >> Beta-prop_Vps41 Vps42 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.9 0.1 0.00018 0.14 46 80 .. 175 209 .. 150 224 .. 0.80 2 ? 3.3 0.0 0.074 57 55 88 .. 229 262 .. 214 271 .. 0.79 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00018 Beta-prop_Vps41 46 ntirtfkahrasisslsidtdGeylAsaSmDGtvv 80 +t +t++ah+ ++++l i+++G+ +A+aS Gt++ FUN_000914-T1 175 TTPSTINAHQGELACLAINQQGTQVATASEKGTLI 209 4456899*************************974 PP == domain 2 score: 3.3 bits; conditional E-value: 0.074 Beta-prop_Vps41 55 rasisslsidtdGeylAsaSmDGtvvigslseee 88 a++ ++ ++d+ +l ++S+ Gtv ++ l++ + FUN_000914-T1 229 PATLYCINFSHDSAFLCVSSDKGTVHVFALKNTS 262 5677788888999999999999999998887654 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 5.9 4.6e+03 107 126 .. 22 41 .. 9 45 .. 0.65 2 ! 16.0 0.0 8.3e-06 0.0065 79 164 .. 174 260 .. 149 269 .. 0.76 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 5.9 WD40_MABP1-WDR62_2nd 107 DrsGniriydletleellki 126 +G riy++e l+e +++ FUN_000914-T1 22 TMEGGFRIYNVEPLSEKARV 41 45666777777766666655 PP == domain 2 score: 16.0 bits; conditional E-value: 8.3e-06 WD40_MABP1-WDR62_2nd 79 kkdeseldsknG.vRvlkvspdgkhlasGDrsGn.iriydletleellkie..ahdsevlcleyskpetglkllasasRDRlihvfdve 163 ++ s++++++G + +l ++++g ++a+ +G+ ir++d +t + l+++ a + + c+++s+ +l +s +hvf ++ FUN_000914-T1 174 STTPSTINAHQGeLACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRrgADPATLYCINFSHD---SAFLCVSSDKGTVHVFALK 259 333445566666589************999999747*****99999988753378899999999985...579999999999***9987 PP WD40_MABP1-WDR62_2nd 164 k 164 + FUN_000914-T1 260 N 260 6 PP >> KNTC1_N KNTC1, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.0 0.0066 5.1 47 83 .. 74 110 .. 47 118 .. 0.82 2 ! 8.5 0.0 0.0019 1.5 50 97 .. 209 259 .. 163 269 .. 0.80 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0066 KNTC1_N 47 dksvslfdeicqsvlltLsfdsevdvvalsqdgqfLl 83 + +v ++d++ +++ ++Lsf+++v +v++ +d+ f + FUN_000914-T1 74 NDKVYIWDDVLKELVMELSFGCPVMSVKMRRDKLFVI 110 5699*****************************9987 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0019 KNTC1_N 50 vslfdeicqsvlltLsfdse...vdvvalsqdgqfLlvgersGnlhlihve 97 + +fd+ +++l++L +++ ++++s+d+ fL v +G++h++ + FUN_000914-T1 209 IRVFDTQTKNMLIELRRGADpatLYCINFSHDSAFLCVSSDKGTVHVFALK 259 56788888888888887754222678999*****************99765 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0039 3 35 87 .. 181 236 .. 173 238 .. 0.84 2 ! 8.4 0.0 0.0047 3.6 42 74 .. 233 265 .. 226 273 .. 0.85 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0039 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdge.vrlldvesgklvhslsaksdk..itcle 87 +++++e +la +++G+ a a ++g+ +r++d ++++++ +l+ ++d c++ FUN_000914-T1 181 NAHQGELACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRRGADPatLYCIN 236 56889999******************648************999888864455555 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0047 ANAPC4_WD40 42 tslaWkpdGklLavaysdgevrlldvesgklvh 74 ++++++d +L+v+ ++g+v+++ +++ l + FUN_000914-T1 233 YCINFSHDSAFLCVSSDKGTVHVFALKNTSLNK 265 5899********************999987655 PP >> Beta-prop_IFT122_2nd IFT122 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 2 1.6e+03 38 62 .. 99 123 .. 82 143 .. 0.75 2 ! 14.6 0.0 3e-05 0.024 151 244 .. 176 276 .. 157 279 .. 0.75 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 2 Beta-prop_IFT122_2nd 38 kiavykdrlavqlservviyelsse 62 + + +d+l v ++ r+ +++ ++ FUN_000914-T1 99 SVKMRRDKLFVIFKTRIQVFSFPQD 123 4556678888888888888876544 PP == domain 2 score: 14.6 bits; conditional E-value: 3e-05 Beta-prop_IFT122_2nd 151 fpvellklkssvrclDlsasrkklavvdenskl.lvydlktkellfqeen....ansvawNteled.llcysg.ngtlsikasnfpahq 232 p ++ ++ ++ cl ++++ +++a +e+++l v+d++tk++l++ + a+ N +++ +lc s+ +gt+++ a + + + FUN_000914-T1 176 TPSTINAHQGELACLAINQQGTQVATASEKGTLiRVFDTQTKNMLIELRRgadpATLYCINFSHDSaFLCVSSdKGTVHVFALKNTSLN 264 6889999**********************987527********9998543111255556676666436888873478887777666666 PP Beta-prop_IFT122_2nd 233 qklqGfvvgfkg 244 ++ + +gf g FUN_000914-T1 265 KRSSLAKMGFLG 276 666655666655 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.9 7e+02 15 59 .. 5 47 .. 1 64 [. 0.68 2 ! 10.2 0.0 0.00053 0.41 62 140 .. 175 254 .. 165 258 .. 0.85 3 ? 5.4 0.0 0.016 12 158 192 .. 231 265 .. 223 310 .. 0.71 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.9 Beta-prop_WDR35_TULP_N 15 vklksvaWnkeqgyiavggedglLkvLklesekkeakakglaaks 59 + ++ +n++qg ++ +e g +++ ++e +++a++ +l+++ FUN_000914-T1 5 NDVFHIDFNQDQGCFSCTMEGG-FRIYNVEPLSEKARV-DLNEPC 47 56778999**********9999.588888876655443.333443 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00053 Beta-prop_WDR35_TULP_N 62 smnqtlegHsgavqvvaWNekykkLtssDenGlii.vWmlykgswveeminnrnksvvkdlkWssdgqkicivyedGavi 140 ++ t++ H+g++ ++a N++ ++++++ e+G++i v+ + ++ + e+ + +++ ++ s+d +c+ + G+v FUN_000914-T1 175 TTPSTINAHQGELACLAINQQGTQVATASEKGTLIrVFDTQTKNMLIELRRGADPATLYCINFSHDSAFLCVSSDKGTVH 254 566899******************99999998765489888888888999889999999999999999999999998885 PP == domain 3 score: 5.4 bits; conditional E-value: 0.016 Beta-prop_WDR35_TULP_N 158 klakvewspdgklllfglkegevhvydsegnflsk 192 +l ++++s d+ +l +++ +g vhv+ + + l+k FUN_000914-T1 231 TLYCINFSHDSAFLCVSSDKGTVHVFALKNTSLNK 265 45555666666666666666666666544444433 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 2.4 1.9e+03 39 78 .. 25 65 .. 21 70 .. 0.77 2 ? 13.1 0.0 7.3e-05 0.056 51 140 .. 176 262 .. 145 272 .. 0.82 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 2.4 Beta-prop_HPS5 39 Ggvyifsrealkllqlltake.gaistvaispdedlvavat 78 Gg i++ e l+ ++ +e +is++ + +++lva+++ FUN_000914-T1 25 GGFRIYNVEPLSEKARVDLNEpCQISQTHMMHRCNLVAIVG 65 666677777777777777777689*************9975 PP == domain 2 score: 13.1 bits; conditional E-value: 7.3e-05 Beta-prop_HPS5 51 llqlltakegaistvaispdedlvavatsrglvv.vvelnierkqkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsvtklsssk 140 + +++a++g+ ++ai+++ va a+++g ++ v++ +++k ++ +++ ++ +++s + + +kG+v+v l++++ FUN_000914-T1 176 TPSTINAHQGELACLAINQQGTQVATASEKGTLIrVFD----TQTKNMLIELRRGADPATLYCINFSHDSAFLCVSSDKGTVHVFALKNTS 262 55788999999999999999999999999997641444....4678888888999999999999999999999999999999999999885 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.4 3.1e+02 324 353 .. 6 35 .. 2 46 .. 0.83 2 ? 12.0 0.0 0.00012 0.091 269 359 .. 173 267 .. 160 287 .. 0.77 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.4 Beta-prop_WDR41 324 nvlhiaklpnrqlvscsedgsvriwelrek 353 +v hi +++ sc+ +g ri+++++ FUN_000914-T1 6 DVFHIDFNQDQGCFSCTMEGGFRIYNVEPL 35 6889998899999************99764 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00012 Beta-prop_WDR41 269 dakqeiklsqkleeisiqhlttddecvfaavgrg..iyvyslqakrviayqkkahdsnvlhiaklpnrqlvsc..sedgsvriwelrekkkssa 358 ++ +++ ++ e++ + ++ v +a +g i v++ q+k ++ ++ d l+ +++ c s+ g+v ++ l++ ++ FUN_000914-T1 173 TSTTPSTINAHQGELACLAINQQGTQVATASEKGtlIRVFDTQTKNMLIELRRGADPATLYCINFSHDSAFLCvsSDKGTVHVFALKNTSLNKR 266 4455567788999**************999988854779*********999*************98765444433789********99865444 PP Beta-prop_WDR41 359 e 359 FUN_000914-T1 267 S 267 3 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 3.9 3e+03 172 215 .. 18 63 .. 13 65 .. 0.73 2 ? 13.4 0.0 6.4e-05 0.05 154 228 .. 181 259 .. 164 269 .. 0.74 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 3.9 Beta-prop_WDR36-Utp21_2nd 172 vitagadkklkfwkfkskklletlkleasisklvlh..ressllav 215 ++ ++++ ++++++ +++ ++l+++ + ++ h + ++l+a+ FUN_000914-T1 18 CFSCTMEGGFRIYNVEPLSEKARVDLNEPCQISQTHmmHRCNLVAI 63 5677888888999999999999999998866555542267788887 PP == domain 2 score: 13.4 bits; conditional E-value: 6.4e-05 Beta-prop_WDR36-Utp21_2nd 154 kahkkavrGvavdalnqvvitagadkk.lkfwkfkskklletlklea...sisklvlhressllavalddfsilvvDid 228 +ah++++ +a+++ ++v ta++ ++ +++++ ++k++l +l+ a + + + ++s++l v+ d+ +++v+ ++ FUN_000914-T1 181 NAHQGELACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRRGAdpaTLYCINFSHDSAFLCVSSDKGTVHVFALK 259 7888888899998888888888876542788888888888887654410034456778888999999998888887665 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 6.3e-05 0.049 47 128 .. 179 264 .. 155 313 .. 0.70 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 6.3e-05 EIF3I 47 tyeGheGavwsidvdsettllvtgsadnt.vklWdvetGkelktlet...ktavrsvefsesgkllllvtdkvmgkkseivvldir 128 t + h+G + ++ ++++ t+++t+s t ++++d++t ++l +l+ +++ ++fs+++ l+++ dk + + +++ ++++ FUN_000914-T1 179 TINAHQGELACLAINQQGTQVATASEKGTlIRVFDTQTKNMLIELRRgadPATLYCINFSHDSAFLCVSSDKGTVHVFALKNTSLN 264 56677777777777777777777776654367777777776665543111456667777777777777766655555444444444 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 3.4 2.6e+03 168 184 .. 18 34 .. 9 52 .. 0.74 2 ? 11.5 0.0 0.00022 0.17 193 332 .. 111 251 .. 93 273 .. 0.65 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 3.4 Beta-prop_Aladin 168 llaatpssvfrvwetet 184 +++t++ fr++++e FUN_000914-T1 18 CFSCTMEGGFRIYNVEP 34 68888888888888764 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00022 Beta-prop_Aladin 193 lkgrvqaacwspdgsvll.fateeepviyslsfkeeeseea....gskaavvvadlskveletedeeikv...ggevqslawdpkgerlavll 277 k+r+q ++ d ++l+ f t+e+p ++ ++e+ + ++ +++++dl++ + +t+++ ++ ge la++++g ++a FUN_000914-T1 111 FKTRIQVFSFPQDPKLLFyFDTRENPKGLCVVCPSTERPLMvfpsQKCGSMQLVDLTNRQPDTSTTPSTInahQGELACLAINQQGTQVATAS 203 567777777766666555234445555444444444222224554556678889999888777766444411168888999999999999999 PP Beta-prop_Aladin 278 eeselvavfktrlspvlellPcglvkgeegevpelisFqpnfekgalLtvvwssg 332 e+ +l+ vf t+++++l l +g + ++ +i+F++ + a L v +g FUN_000914-T1 204 EKGTLIRVFDTQTKNMLI----ELRRGADPATLYCINFSH---DSAFLCVSSDKG 251 999999999998777652....233455555555555543...345555555555 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 0.00026 0.2 73 162 .. 168 256 .. 157 266 .. 0.64 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00026 Beta-prop_TEP1_2nd 73 qpekaeslsslsvlrghtgavtccsfsldGgllatggrdrsll.cWdvrvpkaPvlirsllachrdWvtgcaWtkddllvscssd.Gsvgl 161 ++++ ++ ++ s++ h+g ++c + +++G+++at++ +l+ ++d ++ +li + + + +d+ ++ ssd G+v + FUN_000914-T1 168 NRQP-DTSTTPSTINAHQGELACLAINQQGTQVATASEKGTLIrVFDTQT--KNMLIELRRGADPATLYCINFSHDSAFLCVSSDkGTVHV 255 4444.4445567889*********************98887763566666..334444334444445555566655544443333266665 PP Beta-prop_TEP1_2nd 162 W 162 + FUN_000914-T1 256 F 256 5 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.054 42 96 127 .. 178 209 .. 163 222 .. 0.80 2 ? 10.7 0.0 0.00028 0.22 289 360 .. 198 266 .. 179 310 .. 0.80 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.054 Beta-prop_IFT140_1st 96 elpklhkaeitvlewssngsrLvsgdksGvlv 127 ++ ++h+ e+ +l+ +++g++++++ ++G+l+ FUN_000914-T1 178 STINAHQGELACLAINQQGTQVATASEKGTLI 209 3456899**********************997 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00028 Beta-prop_IFT140_1st 289 lLitatge.svirlwdlerddnyvLsldeklgfekgEaincvsyckakgiLaaGtnkGrvalwkkvaessssk 360 ++ta++ ++ir++d + +n++++l + ++ c+++++ ++ L+ +kG+v ++ ++s +++ FUN_000914-T1 198 QVATASEKgTLIRVFDT-QTKNMLIELRRG---ADPATLYCINFSHDSAFLCVSSDKGTVHVFALKNTSLNKR 266 456666543789****6.568999999775...55679**********************9998877665554 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.045 35 119 154 .. 179 215 .. 159 228 .. 0.75 2 ? 5.3 0.0 0.014 10 275 306 .. 232 263 .. 226 281 .. 0.86 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.045 NBCH_WD40 119 sirqhkdvvscvavtsdgsvlatGsydtt.vmvwevl 154 +i+ h+ ++c+a+ ++g+ +at s t + v++++ FUN_000914-T1 179 TINAHQGELACLAINQQGTQVATASEKGTlIRVFDTQ 215 5778888889999999999999988766514455544 PP == domain 2 score: 5.3 bits; conditional E-value: 0.014 NBCH_WD40 275 lnclelsscgeflvcaGdqGqivvrslkslev 306 l c+++s+ fl ++ d+G + v++lk + FUN_000914-T1 232 LYCINFSHDSAFLCVSSDKGTVHVFALKNTSL 263 88**********************99986554 PP >> Beta-prop_NWD2_C NWD2 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.094 73 85 161 .. 179 260 .. 170 271 .. 0.67 2 ? 5.7 0.0 0.013 9.7 306 335 .. 285 314 .. 279 319 .. 0.93 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.094 Beta-prop_NWD2_C 85 lfkeeqkdvkqlllleddtkviavskekea.......ekkakvvvrsiPegekvyefeyevkkkfkkavltadglflvvlavdk 161 + + +q ++ l +++++t+v + s++++ +k+ + +r + +++y ++++ ++ ++++d+ ++ v a+++ FUN_000914-T1 179 TINAHQGELACLAINQQGTQVATASEKGTLirvfdtqTKNMLIELRRGADPATLYCINFSHDS--AFLCVSSDKGTVHVFALKN 260 556677777788888888888888888655566654445555556666677788888888776..4456677766666666554 PP == domain 2 score: 5.7 bits; conditional E-value: 0.013 Beta-prop_NWD2_C 306 ianykvqaelkaiestedgksivlgtvDGs 335 +an+ v ae i + g+s+v +vDG+ FUN_000914-T1 285 LANFTVPAERPCICAFGSGSSVVAVCVDGT 314 8****************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (343 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 534 (0.0209043); expected 510.9 (0.02) Passed bias filter: 465 (0.0182032); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 33 (0.00129184); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 33 [number of targets reported over threshold] # CPU time: 0.38u 0.36s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 3352.86 // Query: FUN_000915-T1 [L=268] Description: FUN_000915 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.17 12.9 1.9 9 7.4 0.0 3.0 3 TMEM141 TMEM141 protein family 3.8 8.0 11.9 1.9 8.9 3.5 2.9 3 BioY BioY family Domain annotation for each model (and alignments): >> TMEM141 TMEM141 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 0.16 2e+03 30 65 .. 34 69 .. 22 73 .. 0.79 2 ? 3.5 0.3 0.011 1.5e+02 23 48 .. 69 94 .. 54 114 .. 0.87 3 ? 7.4 0.0 0.0007 9 49 88 .. 120 160 .. 98 162 .. 0.85 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.16 TMEM141 30 latfvlgtaatfflqklvqkklpyplkwsllvsvva 65 l + ++ ++ +f l kl +++ p ++ ++ s +a FUN_000915-T1 34 LLAIITCFVCVFKLYKLHSHRHSLPNQYIIFYSGIA 69 556788999999999999999999999888877665 PP == domain 2 score: 3.5 bits; conditional E-value: 0.011 TMEM141 23 srallkGlatfvlgtaatfflqklvq 48 ++ ll G+ f l+t+a+f + ++++ FUN_000915-T1 69 AECLLCGINWFYLATTAVFLVTQFIK 94 678999**************999886 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0007 TMEM141 49 kklpyplkwsllvsvvagsvasYkvtsvetkkCqa.lWlal 88 +++ ++ ++++s+++ +va+ + ++e k+C + Wl l FUN_000915-T1 120 RRFSNKVYGAVFISLLTITVAGLALMEIEFKECAEpEWLLL 160 6888899999***********************87479987 PP >> BioY BioY family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 3.5 0.00015 1.9 73 124 .. 42 103 .. 32 114 .. 0.63 2 ? 3.1 1.5 0.0096 1.2e+02 73 127 .. 109 173 .. 98 183 .. 0.63 3 ? -0.2 0.0 0.1 1.3e+03 50 67 .. 231 248 .. 212 266 .. 0.65 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00015 BioY 73 l.........k.kkslaklllallagllviyllGvlwlalvlklslakalalgvlpfipgdl 124 + + ++sl + +++ g++ + l+G+ w++l+++ + + + v f++ FUN_000915-T1 42 VcvfklyklhShRHSLPNQYIIFYSGIAECLLCGINWFYLATTAVFLVTQFIKVCQFLIIAN 103 2233356667447788888999999***************8443333333344444444444 PP == domain 2 score: 3.1 bits; conditional E-value: 0.0096 BioY 73 l........k.kkslaklllallagllviyllGvlwlalvlk.lslakalalgvlpfipgdlika 127 + k +++ +k+ a++++ll+i + G++ + + +k + + l+l+ l +i+ +++ a FUN_000915-T1 109 AarmmgideKfRRFSNKVYGAVFISLLTITVAGLALMEIEFKeCAEPEWLLLSSLEIIIVQVFMA 173 23344445756778888999999***********9999954433333344455555555544443 PP == domain 3 score: -0.2 bits; conditional E-value: 0.1 BioY 50 gvllgptgGYllgFllaa 67 g++l+ ++GY ++++ FUN_000915-T1 231 GIFLKTKAGYTAVYIAVN 248 455666666666665443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (268 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1122 (0.0439225); expected 510.9 (0.02) Passed bias filter: 481 (0.0188295); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2585.12 // Query: FUN_000916-T1 [L=412] Description: FUN_000916 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-51 172.4 0.3 1.1e-26 93.5 0.0 2.2 2 C2 C2 domain 0.0036 17.7 0.4 0.007 16.8 0.0 1.6 2 DOCK-C2 C2 domain in Dock180 and Zizimin proteins ------ inclusion threshold ------ 0.031 14.5 1.6 0.17 12.1 1.4 2.0 2 PTEN_C2 C2 domain of PTEN tumour-suppressor protein Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.5 0.0 1.3e-30 1.1e-26 3 95 .. 160 256 .. 158 263 .. 0.94 2 ! 76.9 0.3 2e-25 1.7e-21 2 103 .. 290 394 .. 289 395 .. 0.94 Alignments for each domain: == domain 1 score: 93.5 bits; conditional E-value: 1.3e-30 C2 3 LevkvieaknLpkkdkkgksdpyvkvkl.kdgkqkkkTkvvkktlnPvWnetftfevpe...leeevLeieVydkdrlskddflGeveiplselds 94 L +k+++a++Lp+kd++g+sdp+vk+ l +d+k+k +T++++k+l+P+Wne f fe l +++L ++V+d+dr+s++d +Ge+eipls++d FUN_000916-T1 160 LLLKILKATGLPAKDFSGTSDPFVKILLlPDKKHKMETRIKRKNLSPTWNEVFRFEGFAhskLLSRTLYLQVLDYDRFSRNDPIGEIEIPLSDVDL 255 6789***************************************************999999*******************************9776 PP C2 95 g 95 g FUN_000916-T1 256 G 256 6 PP == domain 2 score: 76.9 bits; conditional E-value: 2e-25 C2 2 kLevkvieaknLpkkdkkgksdpyvkvkl...kdgkqkkkTkvvkktlnPvWnetftfevpe..leeevLeieVydkdrlskddflGeveiplsel 92 ++ v v++a +L+k+d g++dpyvk++ +++ kkkT +++++ +PvWne+f f+vp ++ ++ ++V+d+dr+++++++G+v ++ ++ FUN_000916-T1 290 RIVVVVMKAMKLKKMDIIGSCDPYVKIYSiygEKRLDKKKTTIKRRNKDPVWNESFFFHVPVdkVRDIRIVFTVMDFDRVTQNEMIGQVILGYRT- 384 6899***************************999999*****9988879***********99999999**************************9. PP C2 93 dsgeeaegwye 103 g++ ++w e FUN_000916-T1 385 -TGTSLRHWTE 394 .9999999976 PP >> DOCK-C2 C2 domain in Dock180 and Zizimin proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 1.1 9.6e+03 60 76 .. 197 213 .. 192 215 .. 0.75 2 ! 16.8 0.0 8.2e-07 0.007 45 98 .. 315 368 .. 267 384 .. 0.80 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.1 DOCK-C2 60 svvlyhnkspkfneeiK 76 + + +n sp++ne ++ FUN_000916-T1 197 TRIKRKNLSPTWNEVFR 213 555667889****9988 PP == domain 2 score: 16.8 bits; conditional E-value: 8.2e-07 DOCK-C2 45 ciygksgeelvtefksvvlyhnkspkfneeiKiklPieltekhHLlftfyhvsc 98 iy+ ge+ +++ k+++ +nk p +ne + ++P++++++ ++ft+ + + FUN_000916-T1 315 KIYSIYGEKRLDKKKTTIKRRNKDPVWNESFFFHVPVDKVRDIRIVFTVMDFDR 368 589999*******************************************99876 PP >> PTEN_C2 C2 domain of PTEN tumour-suppressor protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.13 1.1e+03 5 38 .. 159 192 .. 156 215 .. 0.73 2 ? 12.1 1.4 2e-05 0.17 6 87 .. 289 374 .. 284 380 .. 0.64 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.13 PTEN_C2 5 pltlksiilegiPnfksgggcrpyiriyqnkkkv 38 +l lk + +g+P+ + +g+++p+++i k FUN_000916-T1 159 VLLLKILKATGLPAKDFSGTSDPFVKILLLPDKK 192 5677778889999999999*******97655555 PP == domain 2 score: 12.1 bits; conditional E-value: 2e-05 PTEN_C2 6 ltlksiilegi..Pnfksgggcrpyiriyqnkkkvlstskkykklkey...qqkkiviklpkgllvqGDvlvefyhkgsklekeekm 87 ++ ++++ + ++++ g+c+py++iy+ + + +kk++ +k++ + +++ ++ D+++ f + ++++++ m FUN_000916-T1 289 NRIVVVVMKAMklKKMDIIGSCDPYVKIYSIYGEK-RLDKKKTTIKRRnkdPVWNESFFFHVPVDKVRDIRIVFTVMDFDRVTQNEM 374 55666666544338899999*********976666.455555555555222444556666666666789999998887775554443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (412 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 884 (0.0346056); expected 510.9 (0.02) Passed bias filter: 732 (0.0286553); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4008.48 // Query: FUN_000917-T1 [L=269] Description: FUN_000917 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.8e-13 48.8 3.4 9.8e-13 48.8 3.4 2.2 2 Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain ------ inclusion threshold ------ 0.014 16.2 0.7 0.014 16.2 0.7 2.5 2 MADF_DNA_bdg Alcohol dehydrogenase transcription factor My 0.13 13.7 0.3 0.13 13.7 0.3 2.6 3 Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain Domain annotation for each model (and alignments): >> Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.8 3.4 1.1e-16 9.8e-13 2 88 .. 64 152 .. 63 153 .. 0.88 2 ? 0.1 1.3 0.18 1.5e+03 28 63 .. 212 249 .. 200 259 .. 0.62 Alignments for each domain: == domain 1 score: 48.8 bits; conditional E-value: 1.1e-16 Myb_DNA-bind_4 2 nkWteeetkaLieiwkellelrfqekgkkrnkklweeiaekmaer.gykrspeqckeKwenLkkkYkkekesekgsg...skwpyfeelde 88 +kW++ +++Lie ++e ++++f + k +k+++e+ia++++e + +s eqc +Kw +L++kYk++ +++k++g ++w++ e++ e FUN_000917-T1 64 QKWEDRFVRLLIEKYGE-YKHLFGK-PKTSKKEVFEKIASAFSEAaDVVVSGEQCMRKWLKLEAKYKEVEDNNKRTGranQTWKFHEQIAE 152 59***************.7888**9.6777777**********874789**********************9988885545*****99875 PP == domain 2 score: 0.1 bits; conditional E-value: 0.18 Myb_DNA-bind_4 28 gkkrnkklweeiaekma.ergy.krspeqckeKwenLk 63 +++r++k +++ ae ++ ++y +r+++ +eK++ L+ FUN_000917-T1 212 NRRRKRKSYSSAAEMLSfLQSYtDRKDKAEEEKIKLLR 249 34444456777777777544554677777677766665 PP >> MADF_DNA_bdg Alcohol dehydrogenase transcription factor Myb/SANT-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.2 0.7 1.7e-06 0.014 21 80 .. 88 149 .. 74 151 .. 0.70 2 ? -0.5 1.6 0.28 2.4e+03 17 39 .. 208 230 .. 204 261 .. 0.52 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.7e-06 MADF_DNA_bdg 21 nkeakekaweeiaeelgskvs....veeckkkwknLRdqyrrelrkkksesgeskksrwryfee 80 k+ k++++e+ia+++ + ++ e+c +kw +L +y+ ++k + ++ ++w++ e+ FUN_000917-T1 88 PKTSKKEVFEKIASAFSEAADvvvsGEQCMRKWLKLEAKYKEVEDNNK--RTGRANQTWKFHEQ 149 3455666666666666444443333999************98887777..9999999**99887 PP == domain 2 score: -0.5 bits; conditional E-value: 0.28 MADF_DNA_bdg 17 pdyrnkeakekaweeiaeelgsk 39 + +n+ +k k +++ ae l + FUN_000917-T1 208 KTLKNRRRKRKSYSSAAEMLSFL 230 44455555555555555544444 PP >> Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.19 1.6e+03 68 94 .. 41 67 .. 33 69 .. 0.89 2 ? 13.7 0.3 1.5e-05 0.13 7 70 .. 67 132 .. 63 146 .. 0.83 3 ? -1.0 0.2 0.58 4.9e+03 54 73 .. 210 228 .. 202 259 .. 0.56 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.19 Myb_DNA-bind_3 68 vkelleesgfsWDeetktvtAtdevWk 94 v++ll++ + s+ ee++ +At + W+ FUN_000917-T1 41 VEDLLQQASTSFAEESQSAKATLQKWE 67 7899999999***********999997 PP == domain 2 score: 13.7 bits; conditional E-value: 1.5e-05 Myb_DNA-bind_3 7 ekllvdllleqvkkgnr..iegntfkkeawkeileefnaktgakytkeqlknrlkklrkqyklvke 70 e+ +v+ll+e+ + + +t kke +++i+++f + + ++ eq+ +++ kl+ +yk v++ FUN_000917-T1 67 EDRFVRLLIEKYGEYKHlfGKPKTSKKEVFEKIASAFSEAADVVVSGEQCMRKWLKLEAKYKEVED 132 45677777777665555554579***************************************9986 PP == domain 3 score: -1.0 bits; conditional E-value: 0.58 Myb_DNA-bind_3 54 lknrlkklrkqyklvkelle 73 lknr k rk+y+++ e+l+ FUN_000917-T1 210 LKNRRRK-RKSYSSAAEMLS 228 4444322.444444444433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (269 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1977 (0.0773928); expected 510.9 (0.02) Passed bias filter: 641 (0.025093); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2644.74 // Query: FUN_000918-T1 [L=158] Description: FUN_000918 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0091 16.6 2.8 0.015 15.9 2.8 1.4 1 UPF0547 Uncharacterised protein family UPF0547 Domain annotation for each model (and alignments): >> UPF0547 Uncharacterised protein family UPF0547 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 2.8 5.7e-07 0.015 3 25 .. 6 27 .. 4 28 .. 0.88 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 5.7e-07 UPF0547 3 CPeCeakvPiAakeCphCGyvFe 25 C C a +A+++C CG+vFe FUN_000918-T1 6 CLACNAVTTEACQSCV-CGHVFE 27 777999999*******.*****7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (158 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2221 (0.0869446); expected 510.9 (0.02) Passed bias filter: 1019 (0.0398904); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 1531.97 // Query: FUN_000919-T1 [L=187] Description: FUN_000919 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.079 13.7 0.4 0.2 12.5 0.3 1.8 1 CXCL16 C-X-C motif chemokine 16 domain Domain annotation for each model (and alignments): >> CXCL16 C-X-C motif chemokine 16 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.3 7.8e-06 0.2 3 36 .. 14 47 .. 12 74 .. 0.88 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 7.8e-06 CXCL16 3 gnegSvvGsCsCdkrissesppeaellehlrkkl 36 +n gS GsC+C + +++++ + + ++++r +l FUN_000919-T1 14 SNSGSSDGSCTCGHVFTKKKLIAGKRFSEYRAEL 47 69***************99999888888888766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1035 (0.0405167); expected 510.9 (0.02) Passed bias filter: 601 (0.0235271); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1858.51 // Query: FUN_000920-T1 [L=171] Description: FUN_000920 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00021 21.8 2.4 0.0003 21.3 2.4 1.3 1 UPF0547 Uncharacterised protein family UPF0547 ------ inclusion threshold ------ 0.01 16.4 0.1 0.015 15.8 0.1 1.2 1 Abp2 ARS binding protein 2 0.26 12.0 4.4 0.33 11.7 4.4 1.5 1 MPM1 Mitochondrial peculiar membrane protein 1 0.9 9.9 3.7 0.55 10.6 1.6 1.7 2 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 1.5 10.4 5.0 0.69 11.5 1.7 2.1 3 DUF5302 Family of unknown function (DUF5302) Domain annotation for each model (and alignments): >> UPF0547 Uncharacterised protein family UPF0547 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 2.4 5.9e-08 0.0003 2 25 .. 5 27 .. 4 28 .. 0.93 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 5.9e-08 UPF0547 2 kCPeCeakvPiAakeCphCGyvFe 25 +C C a vP A+k C CG+vFe FUN_000920-T1 5 QCLACNAVVPKASKTCE-CGHVFE 27 6888*************.*****7 PP >> Abp2 ARS binding protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.8 0.1 3e-06 0.015 18 78 .. 5 64 .. 2 79 .. 0.85 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 3e-06 Abp2 18 filyCnpavpldtdtselreafrapPksdgksfstftlfelikkleekeiktWaelalklG 78 +l Cn++vp+ t e ++f+ + + gk+fs + el +le+k++k+ ++ + l FUN_000920-T1 5 QCLACNAVVPKASKTCECGHVFEDVKQIAGKRFSEYRA-ELYWRLESKRMKALSKENQPLQ 64 589*********************************85.9999999999999877666555 PP >> MPM1 Mitochondrial peculiar membrane protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 4.4 6.4e-05 0.33 56 131 .. 24 94 .. 5 161 .. 0.73 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 6.4e-05 MPM1 56 dvendkkeklGlFFkeytdyLnwkskmyelvkekreeeekkrkeekkkakeestpedlmvkksekkdkekkvvsss 131 +v +d+k+ G+ F+ey L w+ + ++ +e++ ++++++++++ e +e+ ++ +++ +++v +s FUN_000920-T1 24 HVFEDVKQIAGKRFSEYRAELYWRLESKRMKALSKENQPLQNSSSDQNNNIE--NENAELSGEDD---NSEVAVKS 94 5789999999**************9887766655555544443333333222..23333333332...22222222 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 1.6 0.00011 0.55 1 22 [. 5 26 .. 5 28 .. 0.95 2 ? -2.8 0.0 1.7 8.5e+03 9 18 .. 121 131 .. 119 132 .. 0.70 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00011 zf-C3HC4_2 1 eCpiCldmlkdplvvtpCgHvf 22 +C C + +++ + +CgHvf FUN_000920-T1 5 QCLACNAVVPKASKTCECGHVF 26 7********************9 PP == domain 2 score: -2.8 bits; conditional E-value: 1.7 zf-C3HC4_2 9 lkdplvvt.pC 18 l++p+ vt pC FUN_000920-T1 121 LSKPVHVTyPC 131 67787777688 PP >> DUF5302 Family of unknown function (DUF5302) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 1.8 9.1e+03 13 29 .. 55 71 .. 48 84 .. 0.54 2 ? 11.5 1.7 0.00013 0.69 18 49 .. 78 109 .. 74 113 .. 0.76 3 ? -1.8 0.0 1.9 9.5e+03 7 16 .. 145 154 .. 141 159 .. 0.75 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.8 DUF5302 13 ALerKnakaargaahad 29 AL + n+ + +++ ++ FUN_000920-T1 55 ALSKENQPLQNSSSDQN 71 44444444444444443 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00013 DUF5302 18 nakaargaahadggskvhgahGpaaakReFRR 49 na+ +++ + ++ + k ++ +G+a +kR+FRR FUN_000920-T1 78 NAELSGEDDNSEVAVKSQRKQGQAPKKRMFRR 109 45555555566666899999***********9 PP == domain 3 score: -1.8 bits; conditional E-value: 1.9 DUF5302 7 KrKFREALer 16 + +F ALe FUN_000920-T1 145 RSRFSKALES 154 6799999995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (171 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1631 (0.0638481); expected 510.9 (0.02) Passed bias filter: 668 (0.0261499); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1662.56 // Query: FUN_000921-T1 [L=124] Description: FUN_000921 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.5 10.7 4.1 0.6 10.5 4.1 1.1 1 MAJIN Membrane-anchored junction protein Domain annotation for each model (and alignments): >> MAJIN Membrane-anchored junction protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 4.1 2.4e-05 0.6 135 212 .. 14 92 .. 5 106 .. 0.68 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 2.4e-05 MAJIN 135 aeavkkkrklveepssp....sragldrakletsseaaskkkplketrrsleekaqqerqktlasdatdvqeqdsklgdnla 212 ++ +++k k++ ++ p +++ ++ ++t+++aa+ kk k+t+r +e++++q r+ as +qe +s++ +l+ FUN_000921-T1 14 EKRMTNKVKRLTQDEQPlsdvENPVSPQPPFKTPARAATFKKTRKNTKRRKETTSRQLRKTKKAS---VLQELHSRFPSALQ 92 3334445454444444411114455578889******************9888888876655555...78899998888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2315 (0.0906244); expected 510.9 (0.02) Passed bias filter: 795 (0.0311216); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1247.43 // Query: FUN_000922-T1 [L=425] Description: FUN_000922 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-33 115.3 0.2 1.8e-18 67.1 0.0 2.4 2 C2 C2 domain ------ inclusion threshold ------ 0.097 13.2 0.1 0.18 12.3 0.1 1.4 1 Calcyon D1 dopamine receptor-interacting protein (calcy 0.13 12.7 2.9 0.58 10.6 3.2 1.8 2 Myc_target_1 Myc target protein 1 Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.1 0.0 2.1e-22 1.8e-18 2 92 .. 164 253 .. 163 264 .. 0.92 2 ! 46.0 0.1 8e-16 6.8e-12 2 91 .. 298 396 .. 297 408 .. 0.81 Alignments for each domain: == domain 1 score: 67.1 bits; conditional E-value: 2.1e-22 C2 2 kLevkvieaknLpkkdkkgksdpyvkvkl.kdgkqkkkTkvvkktlnPvWnetftfevpe..leeevLeieVydkdrlskddflGeveiplsel 92 L+vk++ a+nLp++ +s yv+++l +d+ +k++Tk+ +++nPv+ne+f+f+v l+e++L+ ++++d +s+++ +Gev +++e FUN_000922-T1 164 VLRVKIVTARNLPAN----HSTNYVEIYLlPDRVEKHQTKIRYSNCNPVYNEEFEFDVGYseLSERTLQCCLFSFDGFSRHQSIGEVFYSFGED 253 69**********999....8999*****************999999************9999**************************999992 PP == domain 2 score: 46.0 bits; conditional E-value: 8e-16 C2 2 kLevkvieaknLpkkdkkgksdpyvkvkl...kdgkqkkkTkvvkktlnPvWnetftfevpe..leeevLeieVydkdrlskdd....flGeveip 88 +L+ v++a+ ++ ++ ++p vkv+l +++ +k+kT+v k+tl Pv+ne f+f+vp l++ +L ++V+d+ +++ ++G+ ++ FUN_000922-T1 298 RLTFVVLKARISKNAFPEDLPNPVVKVSLmlaGRQMKKTKTSVAKNTLFPVYNEAFVFDVPLdrLSDVSLLVRVLDSTVDEGERaqvrTIGKSVVG 393 79999999998888877999*****************************************999************76632222335567777776 PP C2 89 lse 91 ++ FUN_000922-T1 394 PDS 396 665 PP >> Calcyon D1 dopamine receptor-interacting protein (calcyon) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 2.2e-05 0.18 62 110 .. 32 79 .. 13 86 .. 0.73 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.2e-05 Calcyon 62 lvpkikeltislteevserlkvtllillalafLacvvlLvvykalkYdq 110 ++ ++ + +++ ++v ++ + + +a+ +L ++ +L++yk+l++ FUN_000922-T1 32 SADIYSAVEVESGDDVKVKVAIGFAVTCAV-LLFAIFILLLYKVLWFKS 79 455666777777788877777777777776.566788999******975 PP >> Myc_target_1 Myc target protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 3.2 6.8e-05 0.58 20 94 .. 50 126 .. 37 148 .. 0.76 2 ? 8.2 2.2 0.00036 3.1 79 183 .. 72 177 .. 69 181 .. 0.66 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 6.8e-05 Myc_target_1 20 dlilaFclSvlvGL..llgaliyvlltwlsRrrasaritrrskrrsrsssssesslsrlgfyrsssydrrsnlslas 94 ++ + F + +v L + + l+y +l + sR as + t+r ++r+ s +e++l+ + r ++ rs++s FUN_000922-T1 50 KVAIGFAVTCAVLLfaIFILLLYKVLWFKSRSNASSKSTQRVVSQPRAPSVTERTLKTSRQQRRHAPLMRSDSSVSE 126 677889998888663345667899999********************988888888888888888777888877654 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00036 Myc_target_1 79 yrsssydrrsnlslasaltfqRqtSleqvdslgrkpsfraSTFhPllqcsklareaeedsqtllprsttastssasaaaslsrpes..fW..gnns 170 y+ + rsn s +s+ + q+ +v + + k s + Pl++ +++ e + ds +++++ s+ss++++++l + e+ ++ ++ FUN_000922-T1 72 YKVLWFKSRSNASSKSTQRVVSQPRAPSVTERTLKTSRQQRRHAPLMRSDSSVSEIGLDSL---SKNNNFSSSSTENSLNLGQLEFevHYdtDTEV 164 5556677888888888766666777777777788888888888888888888888887764...44666777777888888777652244323344 PP Myc_target_1 171 LrgflstqtppPA 183 Lr+ t PA FUN_000922-T1 165 LRVKIVTARNLPA 177 6666666666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (425 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1374 (0.0537874); expected 510.9 (0.02) Passed bias filter: 1034 (0.0404776); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4104.45 // Query: FUN_000923-T1 [L=217] Description: FUN_000923 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.64 9.7 6.0 0.97 9.1 6.0 1.2 1 VSG_B Trypanosomal VSG domain 3.2 8.1 14.8 1.1 9.6 11.9 1.6 1 MAT1 CDK-activating kinase assembly factor MAT1 Domain annotation for each model (and alignments): >> VSG_B Trypanosomal VSG domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 6.0 7.6e-05 0.97 29 137 .. 71 184 .. 69 189 .. 0.80 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 7.6e-05 VSG_B 29 linlaeaelaapkeeqevtaelaeiealNmsladeewqkkfakdkekkkekkkkksakkeceekkekWeeakkaakakkkek......kltrlkks 118 l +l +a+++ +++ +e+++ +++++ l + + + + ++ ++ke+++++ ++k +++ +++k e+W ++++++++ + e+ +++k + FUN_000923-T1 71 LRRLMQADIRRLEKIDEIETLIQDLNGLGLDEQANNLRLTL-QSKEQASVALRDKVKEERDRAKIETWRKKEEEVDKLRLERiaemerLEQERKAR 165 56788999999999999999999999999987776666665.566666******************************999898888755555556 PP VSG_B 119 aaraaaaekikklaeeaaa 137 ++r++ a+ +++la++a+ FUN_000923-T1 166 EERERRARIMAALARKAHN 184 6666667788888888765 PP >> MAT1 CDK-activating kinase assembly factor MAT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 11.9 8.6e-05 1.1 48 130 .. 86 169 .. 82 187 .. 0.87 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 8.6e-05 MAT1 48 eevEdivfnLv.nnidveeTekkleqYekenkeeIlknkekesqeeeeleeleelekeekeekrkeekkeeeeekekkekekee 130 +e+E+++ +L+ ++d + + +l+ ke ++ l+ k ke+++++++e+ ++ e+e ++ + + ++++e+ e+e+k +e++e FUN_000923-T1 86 DEIETLIQDLNgLGLDEQANNLRLTLQSKEQASVALRDKVKEERDRAKIETWRKKEEEVDKLRLERIAEMERLEQERKAREERE 169 68999****984599**************************************************9999999999999888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (217 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2122 (0.0830691); expected 510.9 (0.02) Passed bias filter: 612 (0.0239577); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2157.51 // Query: FUN_000924-T1 [L=369] Description: FUN_000924 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (369 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3783 (0.148092); expected 510.9 (0.02) Passed bias filter: 579 (0.0226659); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 32 (0.00125269); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.45u 0.38s 00:00:00.83 Elapsed: 00:00:00.41 # Mc/sec: 3599.19 // Query: FUN_000925-T1 [L=526] Description: FUN_000925 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.36 11.6 1.2 0.71 10.7 1.2 1.5 1 Flagellin_arch-type Archaeal-type flagellin Domain annotation for each model (and alignments): >> Flagellin_arch-type Archaeal-type flagellin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 1.2 2.8e-05 0.71 30 120 .. 82 170 .. 79 211 .. 0.80 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 2.8e-05 Flagellin_arch-type 30 gflqqkaqetgdesteqvssdleiigdvgdssangtideltiyvkvnaGstpidlnkttisvtddgqvtvltysefgiitisdttasvtn 119 +l+++ +t+d+ +e ss+++ + + +ss+n++ + + + +++n+G t++ +++ + +++d + v + se++++t+ ++t s+t+ FUN_000925-T1 82 RTLSASTRKTYDTDVE--SSGFQQNEKITNSSNNESLSAVLLPLTTNPGETRQVISSCDSGFFQDSTRSVECDSETETSTSGTCTSSYTE 169 5788888889998888..79*******************************999999888888888555555556666665555555554 PP Flagellin_arch-type 120 g 120 FUN_000925-T1 170 R 170 4 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (526 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4297 (0.168213); expected 510.9 (0.02) Passed bias filter: 864 (0.0338227); expected 510.9 (0.02) Passed Vit filter: 158 (0.00618516); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.48u 0.40s 00:00:00.88 Elapsed: 00:00:00.42 # Mc/sec: 5082.94 // Query: FUN_000926-T1 [L=453] Description: FUN_000926 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-21 77.3 0.0 6.9e-12 46.0 0.0 2.7 3 C2 C2 domain 0.0012 19.3 0.0 0.0025 18.3 0.0 1.5 1 PI3K_C2 Phosphoinositide 3-kinase C2 ------ inclusion threshold ------ 0.24 12.5 0.0 0.5 11.5 0.0 1.6 1 Phage_gp49_66 Phage protein (N4 Gp49/phage Sf6 gene 66) fami Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 0.62 5.3e+03 77 91 .. 150 164 .. 137 173 .. 0.76 2 ! 46.0 0.0 8.1e-16 6.9e-12 2 90 .. 170 262 .. 169 276 .. 0.91 3 ! 28.4 0.1 2.5e-10 2.1e-06 2 101 .. 313 417 .. 312 420 .. 0.88 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.62 C2 77 skddflGeveiplse 91 ++++ lG+ +i++s FUN_000926-T1 150 GRNKKLGQLNIKISY 164 789999999999987 PP == domain 2 score: 46.0 bits; conditional E-value: 8.1e-16 C2 2 kLevkvieaknLpkkdkkgksdpyvkvkl.kdgkqkkkTkvvkktlnPvWnetftfevpe...leeevLeieVydkdrlskddflGeveipls 90 L++ ++ +k+ p++d g++d+ v +++ +d++++k+T ++++++nP +ne f+f ++ + ++L + + +d++s+ ++lGe+++pl FUN_000926-T1 170 NLSIFLVTGKDFPPRDYVGSIDTCVNITVlPDRDRRKQTAIHRRSVNPPYNENFVFGIQAgedAHAHSLLLVTFFFDSYSHAHVLGECRVPLI 262 5889999*****************************************************9998888999999999**9***********985 PP == domain 3 score: 28.4 bits; conditional E-value: 2.5e-10 C2 2 kLevkvieaknLpkkdkkgksdp.yvkvkl...kdgkqkkkTkvv.kktlnPvWnetftfevpe..leeevLeieVydkdrlskddflGeveipls 90 +L+v ++++ +L ++++d y k++l +++ k+kT + + v+ne + f v++ l++++L+++V +++ ++k ++Gev+++ + FUN_000926-T1 313 TLTVAIMKGMKLTEG-LFSNVDKlYTKATLfyeGKKLDKRKTGLKaVGEVFTVFNEALLFRVSKekLPRCTLKVSVNHYNVMGKSATIGEVNFNAE 407 799*********776.78888877********99999999**988666667******************************************999 PP C2 91 eldsgeeaegw 101 + g e+ +w FUN_000926-T1 408 S-SVGLEEVHW 417 8.666666666 PP >> PI3K_C2 Phosphoinositide 3-kinase C2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 2.9e-07 0.0025 3 77 .. 333 405 .. 331 406 .. 0.93 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 2.9e-07 PI3K_C2 3 eklyvecqlysggkqlalpvstklksfsfksikwnewitlpikisdLPrsarLvitiwevkgkkkseplGwvnls 77 +kly +++l+++gk+l +t lk+++ + ++ne + + + ++LPr + L ++++ ++++ ks +G+vn++ FUN_000926-T1 333 DKLYTKATLFYEGKKLD-KRKTGLKAVGEVFTVFNEALLFRVSKEKLPRCT-LKVSVNHYNVMGKSATIGEVNFN 405 689*************9.669999999999******************976.9*******************985 PP >> Phage_gp49_66 Phage protein (N4 Gp49/phage Sf6 gene 66) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 5.8e-05 0.5 24 56 .. 374 407 .. 354 443 .. 0.78 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 5.8e-05 Phage_gp49_66 24 etdklTvcvl.vLkNgftvtgesacvdpenfdae 56 ++kl c l v +N ++v+g+sa++ + nf+ae FUN_000926-T1 374 SKEKLPRCTLkVSVNHYNVMGKSATIGEVNFNAE 407 45677888884557******************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (453 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 750 (0.02936); expected 510.9 (0.02) Passed bias filter: 599 (0.0234488); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4497.03 // Query: FUN_000927-T1 [L=368] Description: FUN_000927 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-19 68.9 3.1 3.7e-19 68.9 3.1 1.9 2 Myb_DNA-bind_5 Myb/SANT-like DNA-binding domain 4.7e-05 24.2 0.7 0.00012 22.9 0.7 1.7 1 Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain 0.002 18.9 0.5 0.0048 17.7 0.5 1.6 1 MADF_DNA_bdg Alcohol dehydrogenase transcription factor My Domain annotation for each model (and alignments): >> Myb_DNA-bind_5 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.9 3.1 4.3e-23 3.7e-19 1 76 [. 22 98 .. 22 100 .. 0.98 2 ? -3.2 0.5 1.4 1.2e+04 12 12 .. 343 343 .. 329 360 .. 0.51 Alignments for each domain: == domain 1 score: 68.9 bits; conditional E-value: 4.3e-23 Myb_DNA-bind_5 1 RkknfseeEkevLvelvekrkeilenkksdaatwkaKnraWkeIaervnalgsv.eRtleelkkkwedlkrrtkrkl 76 Rk+nf+e E + L++ e++ ++l +k +daat+k+K ++Wk+I ++n+ +++ Rt+++lk+kw+++ r +k++l FUN_000927-T1 22 RKPNFTEGESLYLISQFERNAKVLTSKLNDAATNKQKVEVWKRICSDYNSKNPIvLRTANDLKRKWKNMVRAAKKEL 98 9****************************************************99*******************997 PP == domain 2 score: -3.2 bits; conditional E-value: 1.4 Myb_DNA-bind_5 12 v 12 + FUN_000927-T1 343 T 343 1 PP >> Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.7 1.4e-08 0.00012 2 69 .. 24 97 .. 23 109 .. 0.85 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.4e-08 Myb_DNA-bind_4 2 nkWteeetkaLieiwke...llelrfqe.kgkkrnkklweeiaekmaergy..krspeqckeKwenLkkkYkke 69 +++te+e + Li+ + l++++++ +k++ ++w+ i ++ ++++ r++ ++k+Kw+n+ + kke FUN_000927-T1 24 PNFTEGESLYLISQFERnakVLTSKLNDaATNKQKVEVWKRICSDYNSKNPivLRTANDLKRKWKNMVRAAKKE 97 6899999999998887767777777777977888899**********9985348***************99997 PP >> MADF_DNA_bdg Alcohol dehydrogenase transcription factor Myb/SANT-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.5 5.7e-07 0.0048 1 64 [. 34 102 .. 34 119 .. 0.84 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 5.7e-07 MADF_DNA_bdg 1 LIelvrehpcLydrshpdyrnkeakekaweeiaeelgskvs.....veeckkkwknLRdqyrrelrkkk 64 LI++ +++ ++ +d +++k ++w++i++ ++sk + ++++k+kwkn+ ++el + + FUN_000927-T1 34 LISQFERNAKVLTSKLNDAATNKQKVEVWKRICSDYNSKNPivlrtANDLKRKWKNMVRAAKKELFESI 102 7888899999999999999999***************999999888888********999999997776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (368 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1201 (0.0470151); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3640.17 // Query: FUN_000928-T1 [L=142] Description: FUN_000928 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-20 71.6 0.0 7.9e-20 71.3 0.0 1.1 1 SSB Single-strand binding protein family 0.0089 15.8 0.0 0.011 15.5 0.0 1.1 1 Beta-prop_BBS7 BBS7 beta-propeller ------ inclusion threshold ------ 0.015 14.9 0.0 0.018 14.7 0.0 1.1 1 DUF1577 Protein of unknown function (DUF1577) Domain annotation for each model (and alignments): >> SSB Single-strand binding protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.3 0.0 9.3e-24 7.9e-20 1 101 [. 29 128 .. 29 131 .. 0.93 Alignments for each domain: == domain 1 score: 71.3 bits; conditional E-value: 9.3e-24 SSB 1 vnkviLvGrltkdpelrytpngnavanftlavnrrfkdqngekeeetdfirvvvfgk.laevaaeylkkGslvyVeGrlqtrkyedqegqkrtste 95 +n+v+L+G ++dp + n+ + ++f+la++ f+ ++++ +++t++++++vf+ l e ++ y++kG++++V+G++q+++y dqeg kr++t+ FUN_000928-T1 29 LNSVQLIGYSGSDPLRG--SNDYQPTKFSLATTVYFQTRDEKLDSRTEWHSISVFKPsLQEKVNAYVRKGTRLFVQGSIQYNNYVDQEGIKRYNTS 122 699**********9754..4678899********9999********************************************************** PP SSB 96 ivaeev 101 iv ++v FUN_000928-T1 123 IVPNDV 128 *98887 PP >> Beta-prop_BBS7 BBS7 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 1.3e-06 0.011 83 135 .. 81 133 .. 76 140 .. 0.93 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.3e-06 Beta-prop_BBS7 83 FdtnltesiksmyvsgsdLlvcgkyvynhykdckdknyylsgdkindvvalpl 135 F+ +l e++++ + +g+ L+v g+ yn+y d + + y ++ ndv++l++ FUN_000928-T1 81 FKPSLQEKVNAYVRKGTRLFVQGSIQYNNYVDQEGIKRYNTSIVPNDVIVLSQ 133 8899**************************************999****9986 PP >> DUF1577 Protein of unknown function (DUF1577) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 2.1e-06 0.018 129 196 .. 59 123 .. 35 134 .. 0.85 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.1e-06 DUF1577 129 kvnledyktklkkkydlveidvFksdeeeklfelvkktkkilyiedtskeesykeeenedfleyekei 196 v ++ +kl ++++ +i+vFk + +ek+ v+k + l+++ + ++y+ +e + ++y+ i FUN_000928-T1 59 TVYFQTRDEKLDSRTEWHSISVFKPSLQEKVNAYVRKGTR-LFVQGSIQYNNYVDQE--GIKRYNTSI 123 57899999*****************************887.8999999999999887..666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 452 (0.0176943); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1423.48 // Query: FUN_000929-T1 [L=582] Description: FUN_000929 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-28 96.6 39.9 0.039 15.6 0.1 12.9 12 SHIPPO-rpt Sperm-tail PG-rich repeat ------ inclusion threshold ------ 0.13 12.2 9.8 0.93 9.4 0.1 3.2 4 HMMR_N Hyaluronan mediated motility receptor N-terminal Domain annotation for each model (and alignments): >> SHIPPO-rpt Sperm-tail PG-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.4 0.00052 6.7 2 29 .. 20 47 .. 19 50 .. 0.85 2 ! 10.7 0.3 0.00011 1.4 2 33 .] 61 88 .. 60 88 .. 0.84 3 ! 13.7 0.0 1.2e-05 0.16 1 13 [. 95 108 .. 95 117 .. 0.81 4 ! 9.2 0.2 0.00034 4.4 3 32 .. 181 209 .. 181 210 .. 0.86 5 ! 10.6 0.2 0.00012 1.5 1 11 [. 218 228 .. 218 247 .. 0.83 6 ! 11.7 0.1 5.4e-05 0.7 1 12 [. 268 288 .. 268 306 .. 0.62 7 ! 10.4 0.1 0.00014 1.8 1 32 [. 313 346 .. 313 347 .. 0.68 8 ! 15.6 0.1 3.1e-06 0.039 1 32 [. 356 391 .. 356 392 .. 0.81 9 ? 4.2 0.0 0.014 1.7e+02 2 31 .. 404 431 .. 403 433 .. 0.79 10 ! 6.6 0.3 0.0023 30 1 31 [. 443 471 .. 443 487 .. 0.65 11 ! 8.5 0.0 0.00056 7.2 2 11 .. 500 509 .. 499 526 .. 0.71 12 ! 6.8 0.0 0.0019 24 1 9 [. 531 539 .. 531 554 .. 0.82 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00052 SHIPPO-rpt 2 PGPGaYnpek..psvkkkkksapaysfgsr 29 +GPG+Y+ + p+ + ap s+ +r FUN_000929-T1 20 VGPGSYEAPEfgPTKYDG--YAPFLSMTTR 47 7*********88777777..9999999988 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00011 SHIPPO-rpt 2 PGPGaYnpekpsvkkkkksapaysfgsrtrrf 33 PGPG+Y+p + ++ + ++++r++rf FUN_000929-T1 61 PGPGQYDPGI--AGER--VRGGSTLANRSSRF 88 ********99..8888..88888888888876 PP == domain 3 score: 13.7 bits; conditional E-value: 1.2e-05 SHIPPO-rpt 1 tPGPGaYnpek.ps 13 tPGPGaYn +k ++ FUN_000929-T1 95 TPGPGAYNLQKrSD 108 8*********9654 PP == domain 4 score: 9.2 bits; conditional E-value: 0.00034 SHIPPO-rpt 3 GPGaYnpek.psvkkkkksapaysfgsrtrr 32 GP +Yn++ ++++ + + ++ +fg+rt++ FUN_000929-T1 181 GPAYYNVNHnDTATVQ--RYRGVHFGNRTSK 209 9********7666666..9*********987 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00012 SHIPPO-rpt 1 tPGPGaYnpek 11 +PGPG+Ynp k FUN_000929-T1 218 GPGPGQYNPFK 228 6********88 PP == domain 6 score: 11.7 bits; conditional E-value: 5.4e-05 SHIPPO-rpt 1 tPGPGaYnpek.........p 12 +PGPG+Y++++ + FUN_000929-T1 268 VPGPGKYEIKSqfsakpiaiS 288 6**********5444444433 PP == domain 7 score: 10.4 bits; conditional E-value: 0.00014 SHIPPO-rpt 1 tPGPGaYnpek.....psvkkkkksapaysfgsrtrr 32 tP+PG+Yn + ++++ +k++p fg+ + r FUN_000929-T1 313 TPAPGTYNDPRnsleiLKRTTGLKRSP---FGQTSVR 346 8**********7665544444444555...7777766 PP == domain 8 score: 15.6 bits; conditional E-value: 3.1e-06 SHIPPO-rpt 1 tPGPGaYnpek....psvkkkkksapaysfgsrtrr 32 tPGPG+Y++++ +k + s+++ fgs ++r FUN_000929-T1 356 TPGPGTYSIPDintnLIRKANVESSRKGAFGSTSSR 391 8**********9999666666667888888888776 PP == domain 9 score: 4.2 bits; conditional E-value: 0.014 SHIPPO-rpt 2 PGPGaYnpekpsvkkkkksapaysfgsrtr 31 PGP +Y ++k+ +p+ f s+t+ FUN_000929-T1 404 PGPAHYITAE--KAQSKDIQPSAAFVSATE 431 *******999..777777888888766665 PP == domain 10 score: 6.6 bits; conditional E-value: 0.0023 SHIPPO-rpt 1 tPGPGaYnpekpsvkkkkksapaysfgsrtr 31 +P PG+Y++ + + + + ys ++r++ FUN_000929-T1 443 NPPPGSYEVRQ--SYDSTQGRVLYSSAQRSN 471 799********..333333444444444444 PP == domain 11 score: 8.5 bits; conditional E-value: 0.00056 SHIPPO-rpt 2 PGPGaYnpek 11 PGPG+Y++ FUN_000929-T1 500 PGPGQYEIHE 509 9*******98 PP == domain 12 score: 6.8 bits; conditional E-value: 0.0019 SHIPPO-rpt 1 tPGPGaYnp 9 tPGPG+Y+ FUN_000929-T1 531 TPGPGSYEF 539 8******85 PP >> HMMR_N Hyaluronan mediated motility receptor N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.22 2.8e+03 4 35 .. 60 93 .. 59 111 .. 0.62 2 ? -1.4 0.1 0.14 1.8e+03 4 17 .. 268 281 .. 266 332 .. 0.66 3 ? 7.3 0.9 0.00031 4 5 40 .. 444 479 .. 442 498 .. 0.67 4 ? 9.4 0.1 7.3e-05 0.93 5 37 .. 500 531 .. 496 551 .. 0.85 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.22 HMMR_N 4 aPppGsYd..vKtsdalkgpvsf.eksqRfrkqka 35 aP pG Yd + ++ ++g+ + ++s+Rf + + FUN_000929-T1 60 APGPGQYDpgI-AGERVRGGSTLaNRSSRFDSKES 93 67888887433.56777766664267777765553 PP == domain 2 score: -1.4 bits; conditional E-value: 0.14 HMMR_N 4 aPppGsYdvKtsda 17 +P pG Y++K+ FUN_000929-T1 268 VPGPGKYEIKSQFS 281 799******97543 PP == domain 3 score: 7.3 bits; conditional E-value: 0.00031 HMMR_N 5 PppGsYdvKts.dalkgpv...sfeksqRfrkqkavesqq 40 PppGsY+v++s d ++g v s ++s+R k+k+ + FUN_000929-T1 444 PPPGSYEVRQSyDSTQGRVlysSAQRSNRNAKKKG----A 479 ********988789999983334455555555554....2 PP == domain 4 score: 9.4 bits; conditional E-value: 7.3e-05 HMMR_N 5 PppGsYdvKtsdalkgpvsfeksqRfrkqkave 37 P pG Y++ sd ++g++ + qRf++qk+ FUN_000929-T1 500 PGPGQYEIHESD-TRGGLMTTRQQRFQPQKSET 531 99**********.899999999********543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (582 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 323 (0.0126444); expected 510.9 (0.02) Passed bias filter: 275 (0.0107653); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 5687.89 // Query: FUN_000930-T1 [L=334] Description: FUN_000930 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-08 35.6 0.0 2.4e-08 35.1 0.0 1.2 1 Hydrolase haloacid dehalogenase-like hydrolase Domain annotation for each model (and alignments): >> Hydrolase haloacid dehalogenase-like hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.1 0.0 9.4e-13 2.4e-08 1 191 [] 70 263 .. 70 263 .. 0.77 Alignments for each domain: == domain 1 score: 35.1 bits; conditional E-value: 9.4e-13 xxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Hydrolase 1 ikavvFDlDGTLtdge...pvvteaiaelasehplakaivaaaedlpipveefta..............rlllgerelleelgdlealveeleaeg 79 +k v++D+ GT++d p+v a+ e + e++p+ ee ++ + +r+++e++ + ++e+ FUN_000930-T1 70 VKGVILDWAGTVVDCGvysPAV--AFMEV-----------FKQEGVPVTTEEAREpmgshkrvhiykmtQMESVRRRWFEKF------GRYPDKED 146 699**********999443444..44444...........677777777788888999999555555444444444455555......55556666 PP xxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx.xxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Hydrolase 80 ltvvlv....ellgvialadelklypgaaealkaLker.Giklailtgdnretaeallre.lGlddyf.dvvisaddvgigkpkpeiklaalerlg 168 + +++ lg i+ +++ ga+e+++ L+ + G+k++ tg +++++ l ++ ++ +y+ dv ++ad+v+++ p p ++ + +l FUN_000930-T1 147 VERMYNnfvpFQLGCILDYSQ--MITGAVETVNMLRNQmGLKIGSTTGFTTPMLDMLKKAaAD-QGYVpDVYVAADEVPQARPYPYMVWMNAIKLD 239 666666676666666666655..*************999************999988888788.99****************************** PP xx.xxxxxxxxxxxxxxxxxxxxx RF Hydrolase 169 vk.peevlmvGDglnDipaakaaG 191 v+ e ++ v+D+++++ + +aG FUN_000930-T1 240 VNpIEAIVKVDDTADGVWEGTSAG 263 996677899****99988777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (334 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 787 (0.0308084); expected 510.9 (0.02) Passed bias filter: 717 (0.0280681); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3277.99 // Query: FUN_000930-T2 [L=293] Description: FUN_000930 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-08 36.0 0.0 1.6e-08 35.6 0.0 1.1 1 Hydrolase haloacid dehalogenase-like hydrolase Domain annotation for each model (and alignments): >> Hydrolase haloacid dehalogenase-like hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.6 0.0 6.4e-13 1.6e-08 1 191 [] 70 263 .. 70 263 .. 0.77 Alignments for each domain: == domain 1 score: 35.6 bits; conditional E-value: 6.4e-13 xxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Hydrolase 1 ikavvFDlDGTLtdge...pvvteaiaelasehplakaivaaaedlpipveefta..............rlllgerelleelgdlealveeleaeg 79 +k v++D+ GT++d p+v a+ e + e++p+ ee ++ + +r+++e++ + ++e+ FUN_000930-T2 70 VKGVILDWAGTVVDCGvysPAV--AFMEV-----------FKQEGVPVTTEEAREpmgshkrvhiykmtQMESVRRRWFEKF------GRYPDKED 146 699**********999443444..44444...........677777777788888999999555555444444444455555......55556666 PP xxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx.xxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Hydrolase 80 ltvvlv....ellgvialadelklypgaaealkaLker.Giklailtgdnretaeallre.lGlddyf.dvvisaddvgigkpkpeiklaalerlg 168 + +++ lg i+ +++ ga+e+++ L+ + G+k++ tg +++++ l ++ ++ +y+ dv ++ad+v+++ p p ++ + +l FUN_000930-T2 147 VERMYNnfvpFQLGCILDYSQ--MITGAVETVNMLRNQmGLKIGSTTGFTTPMLDMLKKAaAD-QGYVpDVYVAADEVPQARPYPYMVWMNAIKLD 239 666666676666666666655..*************999************999988888788.99****************************** PP xx.xxxxxxxxxxxxxxxxxxxxx RF Hydrolase 169 vk.peevlmvGDglnDipaakaaG 191 v+ e ++ v+D+++++ + +aG FUN_000930-T2 240 VNpIEAIVKVDDTADGVWEGTSAG 263 996677899****99988777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (293 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 593 (0.0232139); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2911.10 // Query: FUN_000930-T3 [L=273] Description: FUN_000930 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.8e-09 36.4 0.0 1.3e-08 35.9 0.0 1.2 1 Hydrolase haloacid dehalogenase-like hydrolase Domain annotation for each model (and alignments): >> Hydrolase haloacid dehalogenase-like hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 0.0 5.2e-13 1.3e-08 1 191 [] 9 202 .. 9 202 .. 0.77 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 5.2e-13 xxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Hydrolase 1 ikavvFDlDGTLtdge...pvvteaiaelasehplakaivaaaedlpipveefta..............rlllgerelleelgdlealveeleaeg 79 +k v++D+ GT++d p+v a+ e + e++p+ ee ++ + +r+++e++ + ++e+ FUN_000930-T3 9 VKGVILDWAGTVVDCGvysPAV--AFMEV-----------FKQEGVPVTTEEAREpmgshkrvhiykmtQMESVRRRWFEKF------GRYPDKED 85 699**********999443444..44444...........677777777788888999999555555444444444455555......55556666 PP xxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx.xxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Hydrolase 80 ltvvlv....ellgvialadelklypgaaealkaLker.Giklailtgdnretaeallre.lGlddyf.dvvisaddvgigkpkpeiklaalerlg 168 + +++ lg i+ +++ ga+e+++ L+ + G+k++ tg +++++ l ++ ++ +y+ dv ++ad+v+++ p p ++ + +l FUN_000930-T3 86 VERMYNnfvpFQLGCILDYSQ--MITGAVETVNMLRNQmGLKIGSTTGFTTPMLDMLKKAaAD-QGYVpDVYVAADEVPQARPYPYMVWMNAIKLD 178 666666676666666666655..*************999************999988888788.99****************************** PP xx.xxxxxxxxxxxxxxxxxxxxx RF Hydrolase 169 vk.peevlmvGDglnDipaakaaG 191 v+ e ++ v+D+++++ + +aG FUN_000930-T3 179 VNpIEAIVKVDDTADGVWEGTSAG 202 996677899****99988777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (273 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 494 (0.0193384); expected 510.9 (0.02) Passed bias filter: 462 (0.0180857); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2745.28 // Query: FUN_000931-T1 [L=493] Description: FUN_000931 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-111 372.1 18.3 5.7e-111 371.8 18.3 1.0 1 ERG4_ERG24 Ergosterol biosynthesis ERG4/ERG24 family ------ inclusion threshold ------ 0.081 13.5 0.3 0.33 11.6 0.0 2.0 2 MNE1 Mitochondrial splicing apparatus component 0.16 11.9 5.6 0.56 10.1 4.7 2.2 2 DUF1295 Protein of unknown function (DUF1295) Domain annotation for each model (and alignments): >> ERG4_ERG24 Ergosterol biosynthesis ERG4/ERG24 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 371.8 18.3 6.7e-115 5.7e-111 66 432 .] 120 493 .] 80 493 .] 0.92 Alignments for each domain: == domain 1 score: 371.8 bits; conditional E-value: 6.7e-115 ERG4_ERG24 66 werklftvfllfyvlqavlylllpGkvvkGlpLsngkkLkYkinaiaslllvlaillvlqvtelfeltvlidnfvqlivvailfafalaivlYvrs 161 + ++ +++ ++ lqavlylllpG+v +G+ g+ L+Yk+n+i + ++ + vl + + tv++d+++ l+v++ +f+f l++++Yv++ FUN_000931-T1 120 VTSNAVILYVCWMSLQAVLYLLLPGRVRRGTATPGGNVLSYKCNGISAWIASHLLFGVLVKIGVIDATVISDHWGGLMVISNVFGFCLTLFVYVKA 215 4566778999************************************************************************************** PP ERG4_ERG24 162 llvkerkkdkdlalgglsGnliYDffiGreLnPRlgslDlkmFlelRlgllllllinlaallkqyetygkvtdslllvllaqllYvfdgvkneeav 257 + ++++ d sG+ YDff+G e nPR+g +D+k F++ R+g++ + linl++ +kqy +g v++s++l++l++++Yv+d +ne FUN_000931-T1 216 YSFPSHPED-----RCFSGSSFYDFFMGIEHNPRIGAFDFKLFFNGRPGIVAWTLINLSFTAKQYANFGFVSNSMILLNLLHAMYVVDFFLNESWY 306 ****96666.....789******************************************************************************* PP ERG4_ERG24 258 lttmDittdgFGFmLaFgdlalvPftYslqtlYLsvhPselgwstvavailvvlligyyiFrsansqkneFR............tfPedpklkl.l 340 l t+Di++d FGF La+gd ++ Pf+Y+lq++YLs hP++l+w +++ l++ l gy+iFrs n qk+ FR P++ l FUN_000931-T1 307 LRTIDIAHDHFGFYLAWGDNVWLPFMYTLQSVYLSRHPISLSWW-ALTGTLLIGLSGYFIFRSVNHQKDYFRtamkatgkcviwGKPAKYILAPyS 401 ********************************************.59*************************988888888766555555554424 PP ERG4_ERG24 341 kviqtktGskLlvsGWyalarkinYlgDwlqslswaLatgfqsvlpyfyvlyFlvlLvhReaRDekkCkkkYGedweeYkkkvpykiipyvy 432 + k+ s+Ll sGW++l+r+ nY+gD+l +ls++L +gf +vlpyfy+++ l+lL+hR++RD+ +C++kYG w +Y++ vpy+i+pyv+ FUN_000931-T1 402 TTDADKKYSYLLASGWWGLSRHFNYVGDLLNALSYCLLCGFGHVLPYFYIIFMLILLIHRSFRDDVRCRQKYGVCWSRYCQMVPYRIVPYVF 493 4444577899*********************************************************************************8 PP >> MNE1 Mitochondrial splicing apparatus component # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 3.9e-05 0.33 51 117 .. 57 125 .. 52 136 .. 0.80 2 ? -1.4 0.2 0.39 3.3e+03 49 81 .. 273 305 .. 266 307 .. 0.81 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3.9e-05 MNE1 51 eknfsgvvsalealvklna..dnltgwldndsfhiifkslsnSssakltsltLFkyLkeskkeltksdY 117 +++ ++++ a++ l + +++t wl +ds+++ + s++n +++ tL +++++s+ +t++ + FUN_000931-T1 57 SPALGFSINIMGAFMLLWPplCVATFWLACDSYQCSLGSVGNEILDNISKRTLVQFIRQSAPSVTSNAV 125 556777888888887754422556679*********************************999998765 PP == domain 2 score: -1.4 bits; conditional E-value: 0.39 MNE1 49 aveknfsgvvsalealvklnadnltgwldndsf 81 +++ nf++v + + l+ l+a +++++ n+s+ FUN_000931-T1 273 KQYANFGFVSNSMILLNLLHAMYVVDFFLNESW 305 578899999999999999988888888877776 PP >> DUF1295 Protein of unknown function (DUF1295) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 0.61 5.2e+03 44 64 .. 197 217 .. 178 228 .. 0.63 2 ? 10.1 4.7 6.6e-05 0.56 104 182 .. 334 439 .. 307 463 .. 0.74 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 0.61 DUF1295 44 lvLvvlWglRLalhllrrilk 64 +v+ + g L+l+++++ + FUN_000931-T1 197 MVISNVFGFCLTLFVYVKAYS 217 445556666666666666554 PP == domain 2 score: 10.1 bits; conditional E-value: 6.6e-05 DUF1295 104 pvllanasneeqalkaldviglvlw.lvglvlealaDaQlsef.........................kkdpankgk.vldsGLwrysRHPNYfge 172 ++ + s++ +l++++++g+ l+ l g + +Q+ f +d + k +l+sG w +sRH NY g+ FUN_000931-T1 334 TLQSVYLSRHPISLSWWALTGTLLIgLSGYFIFRSVNHQKDYFrtamkatgkcviwgkpakyilapysTTDADKKYSyLLASGWWGLSRHFNYVGD 429 45566667777788888888876543777777777788888888888888888888888888888887444444444499**************** PP DUF1295 173 alvWwglfli 182 l +++ l+ FUN_000931-T1 430 LLNALSYCLL 439 *999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (493 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 835 (0.0326874); expected 510.9 (0.02) Passed bias filter: 542 (0.0212175); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4743.44 // Query: FUN_000932-T1 [L=708] Description: FUN_000932 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-71 239.2 0.0 1.4e-70 238.2 0.0 1.6 1 Pkinase Protein kinase domain 8.5e-41 138.3 0.2 6e-21 74.7 0.0 2.7 3 cNMP_binding Cyclic nucleotide-binding domain 5.9e-35 121.3 0.0 1.3e-34 120.1 0.0 1.5 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.00018 21.5 7.2 0.00045 20.2 7.2 1.7 1 PKcGMP_CC Coiled-coil N-terminus of cGMP-dependent prot 0.00037 20.3 0.0 0.00081 19.2 0.0 1.6 1 Kinase-like Kinase-like ------ inclusion threshold ------ 0.11 13.4 2.6 0.29 12.1 1.9 2.1 2 Med28 Mediator complex subunit 28 0.12 12.5 0.0 0.32 11.2 0.0 1.6 1 APH Phosphotransferase enzyme family 0.87 10.9 5.3 0.32 12.3 2.0 2.0 2 Pkinase_C Protein kinase C terminal domain Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 238.2 0.0 4.4e-74 1.4e-70 3 262 .] 401 657 .. 399 657 .. 0.97 Alignments for each domain: == domain 1 score: 238.2 bits; conditional E-value: 4.4e-74 Pkinase 3 vleklGeGsfgkVykaveketgkivAiKkikkekakkkke.kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgalse 97 ++++lG G+fg+V ++ +++++++A+K++kk+++ ++++ +++++E +i+ + ++p+ivrl+++f++k++l+++lE + ggel+++l++kg++++ FUN_000932-T1 401 IIKTLGVGGFGRVELVQLANDNRTFAMKTLKKHHIVETRQqEHIMNEKRIMMEANSPFIVRLFKTFTNKKYLFMLLEACLGGELWTILRDKGSFDD 496 6799*******************************999988******************************************************* PP Pkinase 98 eeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYmAPEvlkskkygkkvDvWslGvilyelltg 193 ++++++ ++e++ ylH++g+v+rDlKpeN+L+d+kg K++DFG+ak++ s+ k+ +f+gt+eY+APE++ +k+++ ++D+WslG++++elltg FUN_000932-T1 497 GTTRFYVGCVIEAFTYLHERGIVYRDLKPENLLLDSKGYCKLVDFGFAKRIGSGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMFELLTG 592 ************************************************************************************************ PP Pkinase 194 kppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRlt.....aeellqhpwf 262 +ppf +++ ++++ +l+ + +++p+++ ++a+ l+kkl++ +p++Rl+ ++++++++wf FUN_000932-T1 593 SPPFTGSDPMKTYNIILKG---------IDMIEFPRKVLKNAQALIKKLCRDNPTERLGyqkggLKDIMKNKWF 657 *****99999999999988.........67899**************************888888889999997 PP >> cNMP_binding Cyclic nucleotide-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.7 0.0 1.9e-24 6e-21 2 88 .. 154 235 .. 153 236 .. 0.96 2 ! 60.9 0.1 3.9e-20 1.2e-16 3 86 .. 273 358 .. 271 360 .. 0.91 3 ? -2.8 0.0 2.9 9.2e+03 26 50 .. 411 435 .. 410 439 .. 0.81 Alignments for each domain: == domain 1 score: 74.7 bits; conditional E-value: 1.9e-24 cNMP_binding 2 rsfkagevifregdpadslyivlsGkvkvyrttedGkeqilavlgpGdffGelallggeprsatvvAledsellvipredfleller 88 +++k++e++++egd++ ly++++Gkvkv +++G +il+ +gpG +fGela+l + pr+a+v A++d+++++i+r++f+ ++++ FUN_000932-T1 154 KKWKKDEFVIKEGDQGSDLYVLEEGKVKV---LKEG--AILGQMGPGRVFGELAILYKCPRTASVKAESDVKIWAIDRQTFQTIMMK 235 789**************************...6899..8*****************99*************************9986 PP == domain 2 score: 60.9 bits; conditional E-value: 3.9e-20 cNMP_binding 3 sfkagevifregdpadslyivlsGkvkvyrttedGke.qilavlgpGdffGelallggeprsatvvAled.sellvipredflell 86 + +ge+i+r+g ++d ++i+++G+v v+++ + e +++++lg+GdffGe al g++ r+a+++A + +++lv++re+f++ + FUN_000932-T1 273 FYDEGEYIIRQGARGDTFFIIKKGAVNVTQRPSVHAEpVFVRTLGKGDFFGEKALKGEDLRTANCIAASGgVHCLVLDREAFEAYI 358 5899************************866666666699****************9999********777***********9865 PP == domain 3 score: -2.8 bits; conditional E-value: 2.9 cNMP_binding 26 GkvkvyrttedGkeqilavlgpGdf 50 G+v+++++ d ++ +++l+++ + FUN_000932-T1 411 GRVELVQLANDNRTFAMKTLKKHHI 435 8999999999999888888887766 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 120.1 0.0 4.2e-38 1.3e-34 2 250 .. 400 642 .. 399 645 .. 0.92 Alignments for each domain: == domain 1 score: 120.1 bits; conditional E-value: 4.2e-38 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtlkeea..seeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrk 94 ++ ++lG G fG+V +l +++ + a+Ktlk+++ + +++e++++e ++m++ + p iv+l t+++ l++++e + gG+L ++Lr+ FUN_000932-T1 400 SIIKTLGVGGFGRVELVQLA----NDNRTFAMKTLKKHHivETRQQEHIMNEKRIMMEANSPFIVRLFKTFTNKKYLFMLLEACLGGELWTILRD 490 6789****************....99999******9876225566999**********************************************9 PP PK_Tyr_Ser-Thr 95 kkeklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDvWs 189 k +++ ++ ++ + ++ yL+++ +v rdl N L+++k +k+ DfG a+ + + +k+ + +++apE++ +k ++D Ws FUN_000932-T1 491 -KGSFDDGTTRFYVGCVIEAFTYLHERGIVYRDLKPENLLLDSKGYCKLVDFGFAKRI---GSGRKTWTFCGTPEYVAPEIILNKGHDLSADYWS 581 .67888888888888899****************************************...6667788888889********************* PP PK_Tyr_Ser-Thr 190 fGvllwEiftlgeepykglkneevlelleeger.leqpencpeelyelmkeCweedpeeRpt 250 G+l++E++t g+ p++g ++ ++++ + +g +e p+++ ++ + l+k+ ++ +p+eR FUN_000932-T1 582 LGILMFELLT-GSPPFTGSDPMKTYNIILKGIDmIEFPRKVLKNAQALIKKLCRDNPTERLG 642 **********.*****************776652689**********************975 PP >> PKcGMP_CC Coiled-coil N-terminus of cGMP-dependent protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 7.2 1.4e-07 0.00045 3 35 .] 46 78 .. 44 78 .. 0.96 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 1.4e-07 PKcGMP_CC 3 LllKDERIrELEleLaekdeEIqELkskLDKfq 35 + +KD RI LE+eL + e I L s+LDK++ FUN_000932-T1 46 MKMKDSRILALEQELKRRNEIIRRLESELDKYR 78 68******************************8 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 2.6e-07 0.00081 152 285 .. 505 636 .. 431 640 .. 0.79 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 2.6e-07 Kinase-like 152 lqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvv.seve..kgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysi 244 +i +L++ g+v +++++nllld kg +l +f+ r g + + + + pE+ ++ + d W lG+ ++ + FUN_000932-T1 505 C-VIEAFTYLHERGIVYRDLKPENLLLDSKGYCKLVDFGFAKRIGSGRKtWTFCgtPEYVAPEIILNK----------GHDLSADYWSLGILMFEL 589 5.788889*******************************99999876552333322233334443332..........3356789*********** PP Kinase-like 245 wclklPltlvaeeakeewifklck..kipekv....klLlkkllrys 285 P+t+ + + i+k + + p kv ++L+kkl r + FUN_000932-T1 590 LTGSPPFTGSDPMKTYNIILKGIDmiEFPRKVlknaQALIKKLCRDN 636 *********99999999877766544445444333367777777766 PP >> Med28 Mediator complex subunit 28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 1.9 8.9e-05 0.29 55 102 .] 33 81 .. 24 81 .. 0.79 2 ? -3.4 0.0 5.7 1.8e+04 8 35 .. 352 375 .. 351 383 .. 0.65 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 8.9e-05 Med28 55 lqkrlelsaqkpeevlke.eieeLkaElerKdelikkhkekieeWqsvl 102 + ++ l++++ e +k+ i +L++El+r++e+i++ ++ +++++svl FUN_000932-T1 33 RELQHALQEKNIEMKMKDsRILALEQELKRRNEIIRRLESELDKYRSVL 81 5666777766666655552699************************997 PP == domain 2 score: -3.4 bits; conditional E-value: 5.7 Med28 8 aalkacleslekqeavkksdqseeqkad 35 +a++a + sle +++ k sd+ + + FUN_000932-T1 352 EAFEAYIGSLEDMKTDKYSDK----ERG 375 688888999988855555555....444 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 9.9e-05 0.32 167 197 .. 515 544 .. 505 546 .. 0.84 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 9.9e-05 APH 167 ppvlvHgDlhpgNllvd..dggrvsGviDFeda 197 ++++v +Dl+p Nll+d + + ++DF++a FUN_000932-T1 515 ERGIVYRDLKPENLLLDskGYCK---LVDFGFA 544 689**************655555...9****98 PP >> Pkinase_C Protein kinase C terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 5.2 1.7e+04 14 23 .. 596 605 .. 594 606 .. 0.88 2 ? 12.3 2.0 9.9e-05 0.32 1 23 [. 678 697 .. 678 706 .. 0.71 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 5.2 Pkinase_C 14 FTeepptltp 23 FT +p+ t+ FUN_000932-T1 596 FTGSDPMKTY 605 9******998 PP == domain 2 score: 12.3 bits; conditional E-value: 9.9e-05 Pkinase_C 1 vksetDtsNFDpeFTeepptltp 23 +ks+tD+sNFD ++ + tp FUN_000932-T1 678 IKSPTDASNFD-DYPPDD--ETP 697 89*********.665433..344 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (708 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1061 (0.0415345); expected 510.9 (0.02) Passed bias filter: 721 (0.0282247); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.37u 0.42s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 6755.14 // Query: FUN_000933-T1 [L=1305] Description: FUN_000933 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-10 40.8 0.1 1.6e-09 38.7 0.0 2.2 2 PH PH domain 2e-09 37.8 0.0 5e-09 36.6 0.0 1.6 1 IRS PTB domain (IRS-1 type) 3.7e-05 24.6 0.0 0.00013 22.9 0.0 2.0 1 PH_11 Pleckstrin homology domain Domain annotation for each model (and alignments): >> PH PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.7 0.0 1.9e-13 1.6e-09 2 102 .. 23 131 .. 22 133 .. 0.83 2 ? -3.9 0.0 3 2.6e+04 79 91 .. 377 390 .. 371 391 .. 0.74 Alignments for each domain: == domain 1 score: 38.7 bits; conditional E-value: 1.9e-13 PH 2 vkeGwLlkkgsgkkk.....swkkryfvLkdgs......llyykdk.kskkskepkgsislkgcevvevvasdkekrkfvFelrtsertgdrtlll 85 +k+G+++ k + ++ w+ ++fvL+d++ l yykd+ + + +k+p ++ l+++ +++++ + +++ + r++ l+l FUN_000933-T1 23 IKCGYMMIKRPPTSGkvrikAWQSKFFVLRDTTlngpqrLEYYKDDsSFDLQKSPEYCFYLDSVVFIGE---SRSSKSHNHAIMVVCRKQ-GPLTL 114 89***6655555555599************999*************999999*************9964...355555555555554455.89*** PP PH 86 qaeseeerkeWikaiqs 102 ++see k+Wi+a++ FUN_000933-T1 115 ACDSEEVNKDWIQALNN 131 ***************86 PP == domain 2 score: -3.9 bits; conditional E-value: 3 PH 79 g.drtlllqaesee 91 g d++++lqa+s + FUN_000933-T1 377 GdDEVFFLQASSCD 390 33699*****9976 PP >> IRS PTB domain (IRS-1 type) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.6 0.0 5.8e-13 5e-09 6 87 .. 195 285 .. 190 289 .. 0.91 Alignments for each domain: == domain 1 score: 36.6 bits; conditional E-value: 5.8e-13 IRS 6 kakgknklvpeyllaitkesvvlvdektkevlvtwpltsirrw.........gasktsFsleaGrrcdtgegeltfqTsegeeiaqliasy 87 + +++n+ ++yll+ t ++vl++ +t+ ++v+wp ++r + +++++ +l aG r+ tgeg ++f ++++++i + i++ FUN_000933-T1 195 PHSERNNIRGDYLLCFTGGDLVLHSVSTNMAVVSWPVSHLRSFksesatsagKKDSQLLTLNAGSRSATGEGIFQFFAKDADAIVDEIRQR 285 66789999999********************************9999998844488****************************9999875 PP >> PH_11 Pleckstrin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.0 1.5e-08 0.00013 2 99 .. 23 130 .. 22 131 .. 0.75 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.5e-08 PH_11 2 ikgvyfkv.....krkgllklwkqrwlilrrkv....isLsyYk..segalvpegsvvisrkaftlsrradknedtlefeistiakskksfflkge 86 ik++y+ + k+ +k w+ + ++lr+ +L+yYk s +l + + + +++ + ++++ ++ + ++ +k +++++l+++ FUN_000933-T1 23 IKCGYMMIkrpptSGKVRIKAWQSKFFVLRDTTlngpQRLEYYKddSSFDLQKSPEYCFYLDSVVFIGESRSSKSHNHAIMVVCRK-QGPLTLACD 117 89***99944444446779*************9999999*****552223333445566677777776666666666666666655.79******* PP PH_11 87 nkeekeeWvealk 99 ++e ++W++al FUN_000933-T1 118 SEEVNKDWIQALN 130 ***********96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1305 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1125 (0.0440399); expected 510.9 (0.02) Passed bias filter: 622 (0.0243492); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.47u 0.39s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 12574.41 // Query: FUN_000933-T2 [L=911] Description: FUN_000933 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.9 7.8 4.2 3.4 6.9 4.2 1.4 1 Nucleo_P87 Nucleopolyhedrovirus capsid protein P87 Domain annotation for each model (and alignments): >> Nucleo_P87 Nucleopolyhedrovirus capsid protein P87 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 4.2 0.00013 3.4 262 402 .. 553 688 .. 494 749 .. 0.66 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.00013 Nucleo_P87 262 kknnsaqfdiskhesvedvrefaktvwrakktpmaeqslqspadtpaperslqsPeqtparrkst.kmteeslqsPaqtpawqtpattptretssd 356 + ++++qf+++k+++ + +f k+v++ + s a++ + ++ sP+++ arr+s + +++q + +tp+t+p++e++++ FUN_000933-T2 553 NVDQDGQFEVTKRKDFKA-TKFVKKVFKLSP----KVKRSSNAEARE-SNEQSSPPSERARRESLsPGVAAEFQRRLSGSEVNTPETSPKTERKNS 642 346677999999999876.578899998765....333334444444.344556666666666651555669999999999999999999999999 PP Nucleo_P87 357 teaiksepektleeklreklpsdlsaissvpdkkseasavlptekr 402 + ++k + + e k + p l +is + ++e s++ t+++ FUN_000933-T2 643 RTSPKCFRKISAEGKNSRTSPKCLRKISADGKGRKEVSSPSKTSRK 688 9999999888888888888884444444433333333332211111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (911 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 832 (0.03257); expected 510.9 (0.02) Passed bias filter: 458 (0.0179291); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.38u 0.41s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 8741.80 // Query: FUN_000934-T1 [L=349] Description: FUN_000934 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-99 333.6 22.6 2.9e-99 333.4 22.6 1.0 1 Saf4_Yju2 Saf4/Yju2 protein ------ inclusion threshold ------ 0.1 13.2 0.2 1.8 9.1 0.0 2.3 2 Benyvirus_14KDa Benyvirus 14KDa protein 0.2 11.7 6.9 0.066 13.3 2.1 2.4 2 Zn_Ribbon_TF TFIIB zinc-binding 0.83 9.9 6.5 0.35 11.2 2.0 2.4 2 Chalcone_2 Chalcone isomerase like 2.3 9.0 5.2 24 5.8 0.5 2.5 2 Zn_ribbon_ACC Acetyl-CoA carboxylase zinc finger domain 2.7 7.7 30.4 0.083 12.7 22.3 1.9 2 BUD22 BUD22 4.8 8.2 6.6 16 6.4 0.8 3.1 3 E6 Early Protein (E6) Domain annotation for each model (and alignments): >> Saf4_Yju2 Saf4/Yju2 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 333.4 22.6 7.9e-103 2.9e-99 1 331 [] 9 346 .. 9 346 .. 0.84 Alignments for each domain: == domain 1 score: 333.4 bits; conditional E-value: 7.9e-103 Saf4_Yju2 1 kYyPPDfDpskiprerarknrqlvvRlmaPfnirCktCgeyIykGkkFNarkekvenetYlgipIyrFyiKCtrClaeiefkTDPkntdYvieeGa 96 kYyPPDfD skip+ ++++rq+vvRlmaPfn+rC+tCgeyIykGkkFNarke+v+netYlg+ +rFyi+C+rC +ei+fkTDP+ntdYv+e+Ga FUN_000934-T1 9 KYYPPDFDASKIPKLGLSRDRQYVVRLMAPFNMRCTTCGEYIYKGKKFNARKETVQNETYLGLLRFRFYIRCPRCISEITFKTDPENTDYVCENGA 104 9*********************************************************************************************** PP Saf4_Yju2 97 tRnfeaekleeeeakreekereeeeaedamkklEkrtkdskkemealesLeeLkelnqrqakvdyeamlelrkefreekkereeeeedeealkekl 192 tRnf+a+kl e+e++r ++e+eee+++++mk+lEkrt++sk+em++le+LeeL++ln r+a+v+y+ l l ++++ee +++e+ee de+++++ + FUN_000934-T1 105 TRNFQAQKLLEDEENRRQREEEEEQQNNPMKALEKRTQESKQEMDILEKLEELRDLNTRHANVNYDDLLALNAKAAEELRAKEAEE-DEQEVQAYF 199 ********999999*******************************************************************99999.******999 PP Saf4_Yju2 193 sl.eiiellpede.edkkeaalvegkskslfessekskksekkskptdskkseaskkkkkeslkkslskltkkkadlllvvrkkkke........e 278 +i+++l++ + +d++ea++ e ++ + +s+++++++ ++p+d+ e +kk+k s + s+++l++k+++++lv++kk+++ FUN_000934-T1 200 GSkRIQKRLSDGSdNDSDEADKSEHQT-EDRKSARRKATDILAEDPSDT--PEPVQKKQKPSSNLSIGRLQNKAKLASLVKVKKDRTfghktvtkG 292 776888999888745555555555444.444445555555666677665..488889999999************************877666542 PP Saf4_Yju2 279 sksksksekkeeekkeskeesakeeetssk...kaskskakssglsllaaysdssd 331 +k+++ s ++e++ + ++ ++++t + ka+++k+ +l +l++ys+s+d FUN_000934-T1 293 EKTETVSLTAETKMGLCEYSN-RNDSTA-EsssKADRTKNGLGSLNMLGDYSSSED 346 222222222222222222222.222222.1234788889999999*********98 PP >> Benyvirus_14KDa Benyvirus 14KDa protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.075 2.7e+02 63 90 .. 38 65 .. 28 73 .. 0.70 2 ? 9.1 0.0 0.00049 1.8 59 95 .. 71 107 .. 55 116 .. 0.80 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.075 Benyvirus_14KDa 63 hfnvkcvkcssklkfkkqnkdhlkhlsk 90 fn++c c + + k+ + + +++ FUN_000934-T1 38 PFNMRCTTCGEYIYKGKKFNARKETVQN 65 49*******9998655555555555554 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00049 Benyvirus_14KDa 59 vgrlhfnvkcvkcssklkfkkqnkdhlkhlskGylrk 95 r+ f ++c +c s ++fk + + ++G r FUN_000934-T1 71 LLRFRFYIRCPRCISEITFKTDPENTDYVCENGATRN 107 46999****************9999888888887664 PP >> Zn_Ribbon_TF TFIIB zinc-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.2 0.27 1e+03 20 27 .. 41 48 .. 40 51 .. 0.72 2 ? 13.3 2.1 1.8e-05 0.066 2 24 .. 79 102 .. 78 102 .. 0.92 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.27 Zn_Ribbon_TF 20 lvCpdCGl 27 + C+ CG FUN_000934-T1 41 MRCTTCGE 48 56888886 PP == domain 2 score: 13.3 bits; conditional E-value: 1.8e-05 Zn_Ribbon_TF 2 kCPnCgstn.lveDeergelvCpd 24 +CP C s+ + +D+e++++vC++ FUN_000934-T1 79 RCPRCISEItFKTDPENTDYVCEN 102 7******9889***********96 PP >> Chalcone_2 Chalcone isomerase like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 2.0 9.5e-05 0.35 105 169 .. 134 196 .. 130 210 .. 0.87 2 ? 2.5 0.4 0.042 1.5e+02 28 81 .. 188 242 .. 187 247 .. 0.82 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 9.5e-05 Chalcone_2 105 vrailarakkkkeeekeevgeslkelkslFkrkgsvpkgkeLllerdangsLsvlyeekkkkeve 169 ++a+++r++++ +++ ++ e l+el++l +r+ +v+ ++ L l+ +a+++L + e++++ev+ FUN_000934-T1 134 MKALEKRTQES--KQEMDILEKLEELRDLNTRHANVNYDDLLALNAKAAEELRAKEAEEDEQEVQ 196 68999999999..9999***********************************9988887777655 PP == domain 2 score: 2.5 bits; conditional E-value: 0.042 Chalcone_2 28 atsdikklqkvlnskylskkviat.tleksekeelkkalkdpekseelieeLlde 81 a++d +++q+ + sk ++k++ + ++ ++e ++ +++ +d ++ ++ +++l+e FUN_000934-T1 188 AEEDEQEVQAYFGSKRIQKRLSDGsDNDSDEADKSEHQTEDRKSARRKATDILAE 242 5789999999999999999998874666778899999999999999999888876 PP >> Zn_ribbon_ACC Acetyl-CoA carboxylase zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.5 0.0065 24 3 13 .. 42 52 .. 41 53 .. 0.92 2 ? 5.0 0.4 0.011 40 2 23 .. 78 100 .. 77 102 .. 0.88 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0065 Zn_ribbon_ACC 3 KCpsCgeliyr 13 +C+ Cge iy+ FUN_000934-T1 42 RCTTCGEYIYK 52 7*********7 PP == domain 2 score: 5.0 bits; conditional E-value: 0.011 Zn_ribbon_ACC 2 iKCpsC.geliyrkdLernlsVC 23 i+Cp+C +e++++ d e++ +VC FUN_000934-T1 78 IRCPRCiSEITFKTDPENTDYVC 100 89****88999999999999999 PP >> BUD22 BUD22 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 22.3 2.3e-05 0.083 137 288 .. 114 275 .. 99 278 .. 0.45 2 ? -0.1 1.0 0.17 6.1e+02 267 299 .. 314 347 .. 283 349 .] 0.62 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.3e-05 BUD22 137 lgiekkkkkkkekekkkkkkakkkkkkeeeeeeeesdkedessdsed...............ekeeseddeeeeeeeedeedaed..........d 207 l+ e+++++++e+e+++++ k+ +k+++e++ +e d ++ ++ d + + FUN_000934-T1 114 LEDEENRRQREEEEEQQNNPMKALEKRTQESK-QEMDILEKLEELRDlntrhanvnyddllaL---------------------NakaaeelrakE 187 33333111222222222221111111111111.222222222222224444333333444432.....................033333333333 PP BUD22 208 eeeeeedlsqydg..lla.....sddedednynevtdeesseesdesdssesdsesesessekkkkkkkkkkkakakkptsstfLPsL 288 +ee+e+++++y g +++ +d d+d+++++++++++++s + + ++ e++s+++e+ +kk+k +++ + + +++++L sL FUN_000934-T1 188 AEEDEQEVQAYFGskRIQkrlsdGSDNDSDEADKSEHQTEDRKSARRKATDILAEDPSDTPEPVQKKQKPSSNLSIGRLQNKAKLASL 275 3344444444433122225553433333333445555555555555555555667777777788899999999**99999****9999 PP == domain 2 score: -0.1 bits; conditional E-value: 0.17 BUD22 267 kkkkkkkakakkptsstfLPsL.mgGYisGsedd 299 ++ +++++++k+ +++ L sL m G +s sed+ FUN_000934-T1 314 RNDSTAESSSKADRTKNGLGSLnMLGDYSSSEDS 347 2333333344444477778888888888888885 PP >> E6 Early Protein (E6) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.8 0.0045 16 65 101 .. 34 74 .. 25 83 .. 0.64 2 ? 0.5 0.1 0.32 1.2e+03 68 82 .. 74 88 .. 55 99 .. 0.74 3 ? 2.8 0.7 0.063 2.3e+02 42 95 .. 109 162 .. 93 169 .. 0.73 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0045 E6 65 kslsdleiRCvvClklLseeeKee....lleekesftkvrg 101 + + +++RC++C++ + + K + +++++ + +r FUN_000934-T1 34 RLMAPFNMRCTTCGEYIYKGKKFNarkeTVQNETYLGLLRF 74 5677789*********9998886522224444444444555 PP == domain 2 score: 0.5 bits; conditional E-value: 0.32 E6 68 sdleiRCvvClklLs 82 + + iRC +C++ ++ FUN_000934-T1 74 FRFYIRCPRCISEIT 88 56789*****98765 PP == domain 3 score: 2.8 bits; conditional E-value: 0.063 E6 42 allelllhlerslkakeleevlgkslsdleiRCvvClklLseeeKeelleekes 95 + +ll+ e+ + +e ee+++++++ le R + + +++ eK e l++ ++ FUN_000934-T1 109 QAQKLLEDEENRRQREEEEEQQNNPMKALEKRTQESKQEMDILEKLEELRDLNT 162 4444455556667777888999999********************998776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (349 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2723 (0.106596); expected 510.9 (0.02) Passed bias filter: 699 (0.0273635); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.40u 0.33s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3419.48 // Query: FUN_000935-T1 [L=317] Description: FUN_000935 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-55 189.6 2.3 9.5e-22 78.1 0.1 2.9 3 Beta-prop_WDR5 WDR5 beta-propeller domain 2.6e-45 155.4 0.1 2.2e-43 149.1 0.1 2.1 1 EIF3I EIF3I 1.4e-42 146.1 0.6 1.1e-36 126.7 0.0 2.5 2 Beta-prop_THOC3 THOC3 beta-propeller domain 1.9e-42 142.3 5.6 2.4e-10 40.9 0.0 7.2 7 WD40 WD domain, G-beta repeat 7.6e-40 137.1 0.1 3.6e-21 76.2 0.2 3.0 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1.3e-32 113.5 0.0 7.8e-19 68.3 0.3 3.0 3 WD40_Prp19 Prp19 WD40 domain 1.5e-29 103.6 0.1 3.3e-18 66.4 0.0 3.2 3 WD40_WDHD1_1st WDHD1 first WD40 domain 6.6e-27 95.0 0.0 8.4e-11 42.2 0.0 3.0 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 6.3e-26 91.7 0.1 4.4e-09 36.5 0.0 3.1 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 3.2e-25 89.5 0.0 2e-09 37.7 0.0 4.0 4 Beta-prop_EML_2 Echinoderm microtubule-associated 3.3e-25 89.3 0.1 1.7e-09 37.6 0.0 3.1 3 WD40_Gbeta G protein beta WD-40 repeat protei 4e-21 75.8 0.1 1e-17 64.7 0.0 2.8 2 WDR55 WDR55 4e-20 72.8 0.0 6.8e-07 29.3 0.0 3.3 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 4.4e-19 69.1 0.1 5.3e-08 32.8 0.0 3.2 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 2.5e-16 60.1 0.1 1.2e-06 28.3 0.0 3.8 4 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 4.5e-16 59.2 0.4 8.3e-06 25.4 0.0 3.1 3 Beta-prop_IFT122_1st IFT122 first beta-propeller 1.7e-15 57.5 0.1 7.8e-10 38.9 0.0 3.5 4 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 7e-13 48.9 0.1 2e-08 34.3 0.0 2.7 3 Beta-prop_Aladin Aladin seven-bladed propeller 6.4e-12 45.6 0.0 6.1e-05 22.6 0.0 3.9 4 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 9.4e-12 45.5 0.1 8.6e-09 35.7 0.0 2.5 2 Beta-prop_EML Echinoderm microtubule-associated 1.3e-10 41.8 0.0 0.14 12.9 0.0 5.1 5 ANAPC4_WD40 Anaphase-promoting complex subunit 1.1e-08 35.1 0.1 0.011 15.4 0.0 4.3 5 WDR90_beta-prop_4th WDR90, 4th beta-propeller 3.8e-08 33.1 0.0 0.0066 15.8 0.0 3.9 4 NBCH_WD40 Neurobeachin beta propeller domain 5.3e-08 33.0 0.1 0.24 11.2 0.0 3.5 3 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 1.4e-07 31.0 0.0 0.0076 15.5 0.0 3.4 3 Beta-prop_IFT140_1st IFT140 first beta-propeller 2.4e-07 31.1 0.2 2.4 8.7 0.0 5.1 5 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 3.3e-06 26.7 0.0 0.0078 15.6 0.0 2.8 3 Beta-prop_SCAP SCAP Beta-propeller 1.5e-05 24.9 0.0 5.9e-05 23.0 0.0 1.8 2 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 1.6e-05 25.0 0.0 0.024 14.5 0.0 3.1 2 Beta-prop_RIG_2nd RIG second beta-propeller 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.6 1 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 3.4e-05 23.4 0.0 1.9 7.7 0.0 3.4 4 Beta-prop_SPT8 SPT8 beta propeller 3.4e-05 23.4 0.2 0.077 12.3 0.0 2.4 2 Beta-prop_IP5PC_F IP5P C-F beta-propeller 5.4e-05 23.3 0.0 0.033 14.1 0.0 2.5 3 Beta-prop_EIPR1 EIPR1 beta-propeller 0.00019 21.0 0.1 0.15 11.5 0.0 3.2 3 Beta-prop_VPS8 Vps8 beta-propeller 0.00026 20.6 0.0 0.0015 18.1 0.0 2.1 2 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.00033 20.6 0.1 0.0022 17.8 0.0 2.1 2 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 0.00033 20.6 0.0 0.0018 18.2 0.0 2.1 1 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 0.0004 19.7 0.0 0.011 15.0 0.1 2.2 2 Tricorn_2nd Tricorn protease second beta prope 0.00063 19.8 0.0 0.002 18.2 0.0 1.8 2 B-prop_COPA_B_2nd COPA/B second beta-propeller 0.0013 18.5 0.0 0.18 11.5 0.0 2.9 3 Beta-prop_Vps41 Vps42 beta-propeller 0.0014 19.1 0.0 13 6.4 0.0 3.2 3 RMC1_N Regulator of MON1-CCZ1 complex, N- 0.002 17.9 0.0 1 9.0 0.0 2.2 2 Beta-prop_HPS5 HPS5 beta-propeller 0.0026 17.1 0.2 0.032 13.5 0.0 2.3 2 Beta-prop_WDR75_2nd WD repeat-containing protein 75 se 0.0036 17.1 0.0 0.67 9.6 0.0 1.9 2 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller 0.0044 16.9 0.0 0.03 14.1 0.0 2.0 2 DUF5074 Domain of unknown function (DUF507 0.0081 15.6 0.0 0.73 9.2 0.0 2.2 2 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 ------ inclusion threshold ------ 0.019 14.3 0.0 2.7 7.1 0.0 2.6 3 Nucleoporin_N Nup133 N terminal like 0.059 13.2 0.0 0.29 11.0 0.0 1.9 2 WD40_like WD40-like domain 0.08 12.1 0.0 0.28 10.3 0.0 2.0 2 Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-prope 0.17 11.3 0.0 8.3 5.8 0.0 3.0 4 Ge1_WD40 WD40 region of Ge1, enhancer of mR Domain annotation for each model (and alignments): >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.1 0.1 1.9e-24 9.5e-22 43 211 .. 8 178 .. 2 180 .. 0.93 2 ! 67.5 0.2 3.1e-21 1.6e-18 5 133 .. 98 225 .. 94 228 .. 0.91 3 ! 56.9 0.0 5.3e-18 2.7e-15 7 128 .. 184 303 .. 182 314 .. 0.82 Alignments for each domain: == domain 1 score: 78.1 bits; conditional E-value: 1.9e-24 Beta-prop_WDR5 43 tleghkkGisdvawssd...skllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsdp 134 t++gh++ + ++++s + +l+sa D + ++ + +tg + t++gH+ v + + n++ + ++G++D + ++W++ +g tlp H++ FUN_000935-T1 8 TCSGHTRPVVHLSFSDItphGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTLP-HKHI 101 7899*****9999996433389***************************************************************99996.9*** PP Beta-prop_WDR5 135 vsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvsfvkFspngkyiLastldstirLwdyekekvvk 211 v+ vdf+ +g+ ++++s + l+ri+d ++ + l++ + + + +s ++k++ + d+ +rLwd+++ vk FUN_000935-T1 102 VKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEPDLLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVK 178 *************************************99999***************************98866665 PP == domain 2 score: 67.5 bits; conditional E-value: 3.1e-21 Beta-prop_WDR5 5 hkkavssvkfspdgkllasasaDktikiwdveegkle.ktleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaF 98 hk+ v v fsp+g+ l +as +k+++i+d+++ + e + l+g + i ws+dsk++ s+ +Dk +r+wd++t + +k+ + n v ++ FUN_000935-T1 98 HKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEpDLLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVD-LPNSVSSMVL 191 99999*************************988765526789**************************************9998.68999***** PP Beta-prop_WDR5 99 npkgnllvSGsfDetvrlWdvrtgkclktlpaHsd 133 +++g++lv s+ +t+ Wd+++ + +k+++a +d FUN_000935-T1 192 SKDGSVLV-VSYAKTISFWDTERMENMKSFEAPTD 225 **999998.599*****************998776 PP == domain 3 score: 56.9 bits; conditional E-value: 5.3e-18 Beta-prop_WDR5 7 kavssvkfspdgkllasasaDktikiwdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpk 101 ++vss+ +s+dg++l s kti wd+e+++ +k++e+ ++ i + + + ++ +++ DD ++ +d + gk l+ kgH v cv+++p+ FUN_000935-T1 184 NSVSSMVLSKDGSVLVV-SYAKTISFWDTERMENMKSFEAPTD-IFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPD 276 57999999999999976.5789999999999999999998765.666677777778888999999999999999999999999999999999999 PP Beta-prop_WDR5 102 gnllvSGsfDetvrlWdvrtgkclktl 128 g+l +SGs D t+rlW+ + gk+ FUN_000935-T1 277 GELYASGSEDGTLRLWQHTVGKTYGLW 303 999999999999999999988876655 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 149.1 0.1 4.3e-46 2.2e-43 3 313 .. 6 293 .. 4 302 .. 0.87 Alignments for each domain: == domain 1 score: 149.1 bits; conditional E-value: 4.3e-46 EIF3I 3 PlllkGheRaltqikynr...eGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletkta 95 Pl+ +Gh+R++ ++ ++ +G +l+s+ kd k+ + G+ +Gt+eGh+Gavws +++++t+++tg+ad ++k+W+ +G+e tl +k FUN_000935-T1 6 PLTCSGHTRPVVHLSFSDitpHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTLPHKHI 101 9999**********99754449************************************************************************** PP EIF3I 96 vrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghedgeiskydlktgeklksvkehekqi 191 v+ v+fs++g++ll+ ++ ++++d+++e++e +lk + ++ +alws+ +k++ +g ed ++ +d++t +++k+v+ +++ FUN_000935-T1 102 VKIVDFSPNGHQLLTASNE-----KLMRIFDLQNENAE---PDLLKG--YTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDL-PNSV 186 ************9987654.....45789999876543...333333..3456889*****************************999876.578* PP EIF3I 192 tdlqlskdktylitaskDktaklldvetlevlktykterpvnsaaisplkdfvvlGGGqeamdvtttsaregkfearfyhkifeeeigrvkGHFGP 287 + + lskd ++l+ + kt +++d+e +e +k++++ + + sa++ p+k v GG ++ f+ + +e+ kGHFGP FUN_000935-T1 187 SSMVLSKDGSVLVVS-YAKTISFWDTERMENMKSFEAPTDIFSASLHPTKSCFVAGG-DD-------------FKLYKFDYTDGKELESYKGHFGP 267 **********99975.579999****************************9877655.44.............3222333445679********** PP EIF3I 288 intlavhPdGksyasggEdGyvrvhe 313 + ++ ++PdG+ yasg+EdG +r+ + FUN_000935-T1 268 VHCVRYSPDGELYASGSEDGTLRLWQ 293 **********************9844 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.1 6.3e-06 0.0032 138 201 .. 25 88 .. 8 96 .. 0.88 2 ! 126.7 0.0 2.2e-39 1.1e-36 1 202 [. 98 296 .. 98 312 .. 0.94 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 6.3e-06 Beta-prop_THOC3 138 spdgkllllttgdgtvevlsypsleevktlkahtsnclcvafdpkgrylAvGsaDalvslWDle 201 +p g +l+++++dg+ + + +++ + t+++h++++++ +++++ + A+G+aD ++W++ FUN_000935-T1 25 TPHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNAL 88 47899999*****************************************************975 PP == domain 2 score: 126.7 bits; conditional E-value: 2.2e-39 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgeninl 94 hk+ v+ v++s++G++L ++s+ k +r+++l++++ + lkg t ++++ ws+++ +++ ++++Dk +rlWd+rt +++++v+++++ ++ FUN_000935-T1 98 HKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEP-DLLKGYTVNIRAALWSKDS-KFVFSGGEDKAMRLWDTRTMSEVKKVDLPNSVSSM 189 8999****************************998765.589************9875.89********************************* PP Beta-prop_THOC3 95 awspdGktiavgskddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgdgtvevlsypsleevktlkahtsnclcvafdpkgrylAv 188 s+dG++++v+ +t+s++d+++++ k+ + +++ + + +p++++++++ d ++ ++y++++e+++ k+h + + cv +p+g++ A+ FUN_000935-T1 190 VLSKDGSVLVVSYA-KTISFWDTERMENMKSFEAPTDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYAS 282 ******99998765.8****************************************************************************** PP Beta-prop_THOC3 189 GsaDalvslWDlee 202 Gs+D + +lW + FUN_000935-T1 283 GSEDGTLRLWQHTV 296 **********8765 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.0 0.00016 0.083 6 34 .. 8 39 .. 3 42 .. 0.89 2 ! 24.7 0.2 6.5e-08 3.3e-05 4 39 .] 51 86 .. 48 86 .. 0.94 3 ! 15.3 0.0 6.4e-05 0.033 10 39 .] 98 127 .. 90 127 .. 0.86 4 ! 23.0 0.0 2.3e-07 0.00012 7 39 .] 138 170 .. 135 170 .. 0.93 5 ! 10.9 0.3 0.0016 0.8 12 39 .] 184 210 .. 177 210 .. 0.89 6 ! 9.3 0.0 0.0049 2.5 4 36 .. 217 248 .. 214 251 .. 0.84 7 ! 40.9 0.0 4.8e-13 2.4e-10 1 38 [. 255 292 .. 255 293 .. 0.94 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.00016 WD40 6 tlkgHtsgVtsla...fspdgsllasgsdDgt 34 t++gHt +V l+ + p+g +l+s+++Dg+ FUN_000935-T1 8 TCSGHTRPVVHLSfsdITPHGYFLISACKDGK 39 789**99998999889**************96 PP == domain 2 score: 24.7 bits; conditional E-value: 6.5e-08 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++t++gH+++V+s + + d + a+g++D + k+W+ FUN_000935-T1 51 IGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWN 86 78*****999*************************7 PP == domain 3 score: 15.3 bits; conditional E-value: 6.4e-05 WD40 10 HtsgVtslafspdgsllasgsdDgtvklWd 39 H+ V ++fsp+g+ l+++s + +++d FUN_000935-T1 98 HKHIVKIVDFSPNGHQLLTASNEKLMRIFD 127 75569999*******************998 PP == domain 4 score: 23.0 bits; conditional E-value: 2.3e-07 WD40 7 lkgHtsgVtslafspdgsllasgsdDgtvklWd 39 lkg t ++++ +s d+++++sg++D+ +lWd FUN_000935-T1 138 LKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWD 170 678888899999********************9 PP == domain 5 score: 10.9 bits; conditional E-value: 0.0016 WD40 12 sgVtslafspdgsllasgsdDgtvklWd 39 ++V+s+ s dgs l++ s+ +t+ +Wd FUN_000935-T1 184 NSVSSMVLSKDGSVLVV-SYAKTISFWD 210 579************85.66*******9 PP == domain 6 score: 9.3 bits; conditional E-value: 0.0049 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvk 36 ++++++ +++ s + +p+ s +++g+dD +++ FUN_000935-T1 217 MKSFEAP-TDIFSASLHPTKSCFVAGGDDFKLY 248 5778888.789****************998876 PP == domain 7 score: 40.9 bits; conditional E-value: 4.8e-13 WD40 1 gkllrtlkgHtsgVtslafspdgsllasgsdDgtvklW 38 gk l ++kgH ++V ++++spdg l asgs+Dgt++lW FUN_000935-T1 255 GKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLW 292 577899****999************************* PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.0 7.9e-10 4e-07 109 183 .. 9 86 .. 2 87 .. 0.92 2 ! 76.2 0.2 7.1e-24 3.6e-21 19 173 .. 48 201 .. 46 205 .. 0.93 3 ! 41.3 0.0 3.6e-13 1.8e-10 3 101 .. 198 295 .. 196 311 .. 0.91 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 7.9e-10 Beta-prop_WDR3_1st 109 LkgHkdqvtsvafle...ekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtgssdselrvwk 183 +gH+ +v +++f++ ++ +l+s++kD l + +t+ + t+ gh++ vws +l+kd + +tg++d + +vw+ FUN_000935-T1 9 CSGHTRPVVHLSFSDitpHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWN 86 57***********964447899*******************************************************7 PP == domain 2 score: 76.2 bits; conditional E-value: 7.1e-24 Beta-prop_WDR3_1st 19 gekvatlegeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglf.r 108 g+ + t+eg+k +v + + ++d +k a+G ad s ++w++ sg+ e+t+ Hk+ v++++f+++g++L ++s+++ + ++D+ +e+ FUN_000935-T1 48 GDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTL-PHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEPdL 137 5667899*****************************************9.6********************************99876516 PP Beta-prop_WDR3_1st 109 LkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtg 173 Lkg + ++ ++ +++++k++ s+++D+ ++lWd +t + vk++ + + v s++lskd+++lv+ FUN_000935-T1 138 LKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKV-DLPNSVSSMVLSKDGSVLVVS 201 89**************************************996.56788************9976 PP == domain 3 score: 41.3 bits; conditional E-value: 3.6e-13 Beta-prop_WDR3_1st 3 vavgalekvlvWdlkkgekvatlegeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDt 93 ++v+ + ++ +Wd+++ e+++++e +++ + + +p+++ + +G +d ++ +d+++g+ +++gH + v ++++++dg+ asGs+D FUN_000935-T1 198 LVVSYAKTISFWDTERMENMKSFEAP-TDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDG 287 67888999**************9876.679999999******************************************************* PP Beta-prop_WDR3_1st 94 diivwDvv 101 ++ +w + FUN_000935-T1 288 TLRLWQHT 295 *****755 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.023 12 172 199 .. 8 38 .. 2 46 .. 0.79 2 ! 68.3 0.3 1.5e-21 7.8e-19 21 219 .. 30 224 .. 23 229 .. 0.91 3 ! 41.3 0.0 2.5e-13 1.3e-10 7 92 .. 224 308 .. 221 313 .. 0.88 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.023 WD40_Prp19 172 sleghsgavtslaFSe...NGYyLAsasedg 199 + +gh+ +v l+FS+ GY L sa++dg FUN_000935-T1 8 TCSGHTRPVVHLSFSDitpHGYFLISACKDG 38 5679999999999997444699999999986 PP == domain 2 score: 68.3 bits; conditional E-value: 1.5e-21 WD40_Prp19 21 lvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgdylvsaskDgtwa 116 ++++ +D++ +l + +++ + t++gh+ +v +++++++++ + +++aD +++vw++ + + ++ hk+ v+ +++ p g+ l++as+++ + FUN_000935-T1 30 FLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEE-LTLPHKHIVKIVDFSPNGHQLLTASNEKLMR 124 6789999**************************************************9776544.4457999************************ PP WD40_Prp19 117 lhdletgktllkvkdeeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsasedgtvklWDLRklknf 212 + dl++++ ++ + + +i +a + D +++ G +d+++++WD ++ + v++++ ++v+s+ +S +G L+++ ++ t+++WD +++n+ FUN_000935-T1 125 IFDLQNENAEPDLLKGY-TVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVD-LPNSVSSMVLSKDGSVLVVSYAK-TISFWDTERMENM 217 *****999888876654.579***********************************98.6679***************9988.************* PP WD40_Prp19 213 ktlelde 219 k++e+++ FUN_000935-T1 218 KSFEAPT 224 **99876 PP == domain 3 score: 41.3 bits; conditional E-value: 2.5e-13 WD40_Prp19 7 pgilaldlnpsdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhka 92 +i + +l+p+ k+ +++GG D ++ fd +++k l+++kgh v +v+++p+ ++ s+s+D+t r+w+++ +t + ++ ++ FUN_000935-T1 224 TDIFSASLHPT-KSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQHTVGKTYGLWRAVNN 308 67889999997.68999******************************************************998777666665555 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0059 3 122 151 .. 7 39 .. 2 57 .. 0.86 2 ! 26.2 0.0 1.1e-08 5.7e-06 89 162 .. 61 133 .. 57 144 .. 0.89 3 ! 66.4 0.0 6.5e-21 3.3e-18 11 168 .. 148 305 .. 139 315 .. 0.84 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0059 WD40_WDHD1_1st 122 ktleghkapvlsval...dpkgeylaSsscDGt 151 +t++gh+ pv +++ p g +l+S++ DG+ FUN_000935-T1 7 LTCSGHTRPVVHLSFsdiTPHGYFLISACKDGK 39 689*********98733369************6 PP == domain 2 score: 26.2 bits; conditional E-value: 1.1e-08 WD40_WDHD1_1st 89 vthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskec 162 v + +l+kd ++ a g++Df+ kv + +++++tl hk+ v+ v+++p+g+ l ++s + ++i+d+++++ FUN_000935-T1 61 VWSATLNKDATKAATGAADFSAKVWNALSGDEELTL-PHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENA 133 556789********************9888877776.6********************************9875 PP == domain 3 score: 66.4 bits; conditional E-value: 6.5e-21 WD40_WDHD1_1st 11 vcysedgkkliTcGsDgdvriwegledddpksikvgekatai.avksdklvvatddntvqlytfpegekdgiltrftap..vthialskdgklla 102 +s+d k++ ++G+D +r+w++ ++ k++++ +++ ++ +k++ ++v + ++t++ + e+ + + +f+ap + + +l+++++ + FUN_000935-T1 148 ALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNSVSSMvLSKDGSVLVVSYAKTISF---WDTERMENMKSFEAPtdIFSASLHPTKSCFV 239 5689***********************************9883556778888886666655...55556666666776622667788999***** PP WD40_WDHD1_1st 103 agseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkv 168 ag++Df++ + +d+++ +++gh +pv +v+++p ge+ aS s DGt+++W+ + +++ ++ FUN_000935-T1 240 AGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQHTVGKTYGLWRA 305 ******************************************************998887766655 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 8e-09 4.1e-06 89 194 .. 9 116 .. 2 117 .. 0.85 2 ! 42.2 0.0 1.6e-13 8.4e-11 52 165 .. 184 295 .. 180 306 .. 0.88 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 8e-09 WD40_CDC20-Fz 89 leghssrvgalaw.....nenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaa 179 ++gh+ v l++ ++ l+s ++dgk + + t ++ + t+++hk+ v + ++++d + A+G+ d + k+w++ s ++ l+l hk FUN_000935-T1 9 CSGHTRPVVHLSFsditpHGYFLISACKDGKPMLRQGDTGDW--IGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTL-PHKHI 101 56777777777774443244569**********999999986..579**********************************999988887.5**** PP WD40_CDC20-Fz 180 vkAlaWcpwkkslLa 194 vk ++++p+ ++lL FUN_000935-T1 102 VKIVDFSPNGHQLLT 116 *********999985 PP == domain 2 score: 42.2 bits; conditional E-value: 1.6e-13 WD40_CDC20-Fz 52 dyvtsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvga.lawnenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspd 146 ++v+s s+dg++L+v ++ ++++wd+e+++ ++++e+ ++ +a l +++ +++G +d k++ +D + +++k+h + v +++spd FUN_000935-T1 184 NSVSSMVLSKDGSVLVVSYA-KTISFWDTERMENMKSFEAPTDIFSAsLHPTKSCFVAGGDDFKLYKFDYTDGKE--LESYKGHFGPVHCVRYSPD 276 68999************997.69***************99886443314447889****************9974..4789*************** PP WD40_CDC20-Fz 147 grllAsGgndntvkiwdlr 165 g+l AsG++d+t+++w++ FUN_000935-T1 277 GELYASGSEDGTLRLWQHT 295 ****************975 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.8 0.0 1.5e-08 7.8e-06 48 109 .. 26 87 .. 14 95 .. 0.90 2 ! 36.5 0.0 8.7e-12 4.4e-09 192 288 .. 75 171 .. 75 177 .. 0.91 3 ! 34.7 0.0 2.9e-11 1.5e-08 178 289 .. 186 295 .. 181 299 .. 0.72 Alignments for each domain: == domain 1 score: 25.8 bits; conditional E-value: 1.5e-08 Beta-prop_WDR3_2nd 48 pgdrhvlvgtkdGklevldlasaelletieahegavwsvaltpdekglvtggaDkkvkfwef 109 p +++ ++kdGk ++ + ++++ + t+e h+gavws +l++d+++ tg+aD + k+w+ FUN_000935-T1 26 PHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNA 87 5555677789**************************************************85 PP == domain 2 score: 36.5 bits; conditional E-value: 8.7e-12 Beta-prop_WDR3_2nd 192 tgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkvkyWDadkfe.kiqtleghagevwalavsskgkfvvsashDk 281 tg+aD + k+w GD + + h+ v v f p+ H+l++a+++k ++ +D ++ + + l+g + +++a s+++kfv s+++Dk FUN_000935-T1 75 TGAADFSAKVWNALSGDEELT-LPHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENaEPDLLKGYTVNIRAALWSKDSKFVFSGGEDK 164 89***************8766.57******************************87755156779************************** PP Beta-prop_WDR3_2nd 282 siRlwer 288 ++Rlw+ FUN_000935-T1 165 AMRLWDT 171 *****74 PP == domain 3 score: 34.7 bits; conditional E-value: 2.9e-11 Beta-prop_WDR3_2nd 178 vlsldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkvkyWDadkfekiqtleghagevwalavs 268 v s+ +s+D++++v s k+i +w ++ + ks+ a +d + s ++ p + + g d k+ ++D +++ + +gh g v+++ s FUN_000935-T1 186 VSSMVLSKDGSVLVV-SYAKTISFWDTERMENMKSFEAPTD-IFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYS 274 667777777777765.4557788888887777788777554.6777777777777777777777777777777777788888888888888 PP Beta-prop_WDR3_2nd 269 skgkfvvsashDksiRlwert 289 +g++ +s+s+D ++Rlw++t FUN_000935-T1 275 PDGELYASGSEDGTLRLWQHT 295 888888888888888888776 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.1 52 119 161 .. 8 53 .. 4 64 .. 0.77 2 ! 28.6 0.0 2.3e-09 1.2e-06 14 140 .. 32 158 .. 23 160 .. 0.85 3 ! 19.5 0.0 1.4e-06 0.00072 14 58 .. 158 202 .. 156 204 .. 0.94 4 ! 37.7 0.0 4e-12 2e-09 17 111 .. 201 295 .. 200 312 .. 0.91 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.1 Beta-prop_EML_2 119 klkghssfithlDwse...dskylqsnsgdyellfwdaktgkqvts 161 +++gh+ +++hl +s+ + +l s ++d++ ++ + +tg+ + + FUN_000935-T1 8 TCSGHTRPVVHLSFSDitpHGYFLISACKDGKPMLRQGDTGDWIGT 53 799**********998666788999999999888777777766655 PP == domain 2 score: 28.6 bits; conditional E-value: 2.3e-09 Beta-prop_EML_2 14 vTagdDktvrlWdlekkklvakvkle.kearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiy 106 ++a++D+ +l + ++ + + + + ++ s+++++d + a G +d s v++a +++e ++ +k+ ++ + fsp+g+ L +s+++ + FUN_000935-T1 32 ISACKDGKPMLRQGDTGDWIGTFEGHkGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTLP-HKHIVKIVDFSPNGHQLLTASNEKLMR 124 566666666666666666666665441466899999********************9999998886.5789*********************** PP Beta-prop_EML_2 107 lYdvskkykkvgklkghssfithlDwsedskylq 140 ++d++++ + lkg + i+ ws+dsk++ FUN_000935-T1 125 IFDLQNENAEPDLLKGYTVNIRAALWSKDSKFVF 158 *******************************986 PP == domain 3 score: 19.5 bits; conditional E-value: 1.4e-06 Beta-prop_EML_2 14 vTagdDktvrlWdlekkklvakvklekearsvafspdgkllavGl 58 +++g+Dk +rlWd+++ + v+kv+l ++++s+ +s+dg++l+v + FUN_000935-T1 158 FSGGEDKAMRLWDTRTMSEVKKVDLPNSVSSMVLSKDGSVLVVSY 202 789***************************************986 PP == domain 4 score: 37.7 bits; conditional E-value: 4e-12 Beta-prop_EML_2 17 gdDktvrlWdlekkklvakvklekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylYdv 110 ++ kt+ +Wd+e+ + +++ + +++ s++++p ++ +++G +d +++ +d ++++e+ + k + +++++++spdg+l a gs+d+++ l++ FUN_000935-T1 201 SYAKTISFWDTERMENMKSFEAPTDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQH 294 77899*************************************************************************************9985 PP Beta-prop_EML_2 111 s 111 + FUN_000935-T1 295 T 295 4 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.6 0.0 3.4e-12 1.7e-09 158 258 .. 32 131 .. 8 135 .. 0.89 2 ! 14.4 0.0 4e-05 0.02 51 98 .. 138 185 .. 134 192 .. 0.90 3 ! 34.5 0.0 3.1e-11 1.6e-08 152 255 .. 192 294 .. 184 312 .. 0.91 Alignments for each domain: == domain 1 score: 37.6 bits; conditional E-value: 3.4e-12 WD40_Gbeta 158 vtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsddatcrlf 253 +++ d l + +tg+ +f gh g v s +l d+ +ga+d sak+w+ g t + h+ ++ + f png+ l t s++ r+f FUN_000935-T1 32 ISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELT-LPHKHIVKIVDFSPNGHQLLTASNEKLMRIF 126 556667777888899*****************************************99987777.5799999************************ PP WD40_Gbeta 254 dlrad 258 dl+ + FUN_000935-T1 127 DLQNE 131 **875 PP == domain 2 score: 14.4 bits; conditional E-value: 4e-05 WD40_Gbeta 51 lrghlakiyamhwgtdsrllvsasqdgkliiwdsyttnkvhaiplrss 98 l+g+ +i a w+ ds+++ s +d + +wd+ t v+ + l s FUN_000935-T1 138 LKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNS 185 89999***********************************99988655 PP == domain 3 score: 34.5 bits; conditional E-value: 3.1e-11 WD40_Gbeta 152 lddnqivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsdd 247 d ++ s t ++wd e ++ +f d++s sl p fv+g d +d +g +++ gh + ++ + p+ge +a+gs+d FUN_000935-T1 192 SKDGSVLVVSYAKTISFWDTERMENMKSFEAP-TDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSED 286 56778888899999*************99876.59************************************************************* PP WD40_Gbeta 248 atcrlfdl 255 t rl++ FUN_000935-T1 287 GTLRLWQH 294 *****875 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.006 3.1 50 123 .. 10 86 .. 3 97 .. 0.84 2 ! 64.7 0.0 2e-20 1e-17 51 249 .. 97 293 .. 89 303 .. 0.89 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.006 WDR55 50 ehhkkscraveFse...dGkklfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWD 123 + h++ + +++Fs+ G l+s+ kD + ++ +tg+++ ++e + ++ l d + atG d k+W FUN_000935-T1 10 SGHTRPVVHLSFSDitpHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWN 86 567777777777743338***************************9877777778888899999************6 PP == domain 2 score: 64.7 bits; conditional E-value: 2e-20 WDR55 51 hhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiys.llvidenllatGdddGtvklWDlRkkkavmelkehedyisdlvv 145 hk+ ++ v Fs +G++l+++s++k ++++d+++++ + + k + i + l d++++++G +d ++lWD+R+ ++v +++ + +s++v+ FUN_000935-T1 97 PHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEPDLLKGYTVNIRAaLWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVD-LPNSVSSMVL 191 599999********************************999999999987516667888999*****************999986.6789****** PP WDR55 146 deekklLlatsgdGtltvfnirkkklevqseeyeeellslalvkeekkvvvGsseGklylfnwgefgahsdrfpghkesidclvpi.tenivvtgs 240 +++ +L+++ t++++++++ +++s e +++ s +l +++ v+G ++ kly f++ + g+ ++++gh ++c+ + ++ gs FUN_000935-T1 192 SKDGSVLVVSYA-KTISFWDTERM-ENMKSFEAPTDIFSASLHPTKSCFVAGGDDFKLYKFDYTD-GKELESYKGHFGPVHCVRYSpDGELYASGS 284 *******99888.899***99865.578999********************************98.77799***********97551668999*** PP WDR55 241 eDGiiRavh 249 eDG++R+ + FUN_000935-T1 285 EDGTLRLWQ 293 ******976 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 1.5e-06 0.00077 228 304 .. 46 122 .. 28 133 .. 0.88 2 ! 24.6 0.1 3.6e-08 1.8e-05 223 303 .. 124 205 .. 118 207 .. 0.84 3 ! 29.3 0.0 1.3e-09 6.8e-07 172 273 .. 197 298 .. 196 312 .. 0.93 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1.5e-06 Beta-prop_WDR36-Utp21_2nd 228 dtrrvvRkfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvflvesaatslslsptgdfLatahvddl 304 dt + +f+ghk+ + +t+++da t + D + ++w+ sg ++ +++++ +++sp+g+ L ta ++l FUN_000935-T1 46 DTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTLPHKHIVKIVDFSPNGHQLLTASNEKL 122 77788999**************************************9999999**************9999877664 PP == domain 2 score: 24.6 bits; conditional E-value: 3.6e-08 Beta-prop_WDR36-Utp21_2nd 223 lvvDidtrrvvRk.fsghknritDltfspdarWlitasmDstirtwdlpsgkliDvflvesaatslslsptgdfLatahvdd 303 +++D++ +++ ++g++ +i+ + +s+d++++ + + D ++r wd + + + +++ + s+ ls g +L+ ++++ FUN_000935-T1 124 RIFDLQNENAEPDlLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNSVSSMVLSKDGSVLVVSYAKT 205 566666655544316899999******************************99*9999************999999988765 PP == domain 3 score: 29.3 bits; conditional E-value: 1.3e-09 Beta-prop_WDR36-Utp21_2nd 172 vitagadkklkfwkfkskklletlkleasisklvlhressllavalddfsilvvDidtrrvvRkfsghknritDltfspdarWl 255 v+ ++ k++ fw+ ++ + +++++ + i + lh s ddf++ +D + + +++gh + ++ + +spd+ FUN_000935-T1 197 VLVVSYAKTISFWDTERMENMKSFEAPTDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELY 280 56678889********************************9999**************************************** PP Beta-prop_WDR36-Utp21_2nd 256 itasmDstirtwdlpsgk 273 + s D t+r w+ + gk FUN_000935-T1 281 ASGSEDGTLRLWQHTVGK 298 ************987776 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.0 0.0 0.00023 0.12 149 204 .. 30 87 .. 24 97 .. 0.80 2 ! 32.8 0.0 1e-10 5.3e-08 88 230 .. 97 235 .. 87 255 .. 0.83 3 ! 21.1 0.0 3.8e-07 0.0002 84 127 .. 259 302 .. 247 309 .. 0.86 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00023 Beta-prop_TEP1_2nd 149 llvscssdGsvglWdiekeqrlgkflGhqsavsavvavee..hvvsvgrdGllkvWdl 204 +l+s+ +dG l + ++++ +g+f Gh+ av +++ ++ + + + d + kvW+ FUN_000935-T1 30 FLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDatKAATGAADFSAKVWNA 87 79******************************88877766223455567889999985 PP == domain 2 score: 32.8 bits; conditional E-value: 1e-10 Beta-prop_TEP1_2nd 88 ghtgavtccsfsldGgllatggrdrsllcWdvrvpka.PvlirsllachrdWvtgcaWtkdd.llvscssdGsvglWdiekeqrlgkflGh 176 h+ v fs++G++l t+++++ + ++d+++ +a P l++ ++ + + W kd+ ++ s+ +d +++lWd ++ +++k FUN_000935-T1 97 PHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAePDLLKGYTV----NIRAALWSKDSkFVFSGGEDKAMRLWDTRTMSEVKKVDLP 183 58899999************************998543888777766....577899*9885267799*******************9999 PP Beta-prop_TEP1_2nd 177 qsavsavvaveehvvsvgrdGllkvWdlqGveltsikahsgqisqcaaalePre 230 +s s v++ + v+ v+ ++ Wd + +e +k+ ++++ +a l+P++ FUN_000935-T1 184 NSVSSMVLSKDGSVLVVSYAKTISFWDTERMEN--MKSFEAPTDIFSASLHPTK 235 998899999999****************99984..4555556655666666655 PP == domain 3 score: 21.1 bits; conditional E-value: 3.8e-07 Beta-prop_TEP1_2nd 84 svlrghtgavtccsfsldGgllatggrdrsllcWdvrvpkaPvl 127 + +gh g+v c +s+dG+l a+g+ d +l +W v k+ l FUN_000935-T1 259 ESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQHTVGKTYGL 302 5679******************************9888777555 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.0 2.3e-09 1.2e-06 125 205 .. 53 132 .. 41 139 .. 0.91 2 ! 9.5 0.1 0.0012 0.6 125 165 .. 137 177 .. 134 190 .. 0.87 3 ? -1.3 0.0 2.2 1.1e+03 353 368 .. 187 202 .. 184 215 .. 0.77 4 ! 17.2 0.0 5.4e-06 0.0027 68 101 .. 263 296 .. 252 309 .. 0.88 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 2.3e-09 Beta-prop_CAF1B_HIR1 125 vlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkk 205 ++ Gh+ v+ + +d++k +g+ D +a +W+ g + l hk+ v+ v + P+++ + t+s ++ +rifd+++++ FUN_000935-T1 53 TFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEELTL-PHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNEN 132 689*********************************99986555.79******************************9986 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0012 Beta-prop_CAF1B_HIR1 125 vlrGhledvyDlswspdskklisgsvDntailWdvekgkkl 165 +l+G++ ++ ws+dsk++ sg D + lWd + +++ FUN_000935-T1 137 LLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEV 177 689999999999**********************8876655 PP == domain 3 score: -1.3 bits; conditional E-value: 2.2 Beta-prop_CAF1B_HIR1 353 tDlaWssdgkllvvss 368 + + s+dg++lvvs FUN_000935-T1 187 SSMVLSKDGSVLVVSY 202 6678899999999994 PP == domain 4 score: 17.2 bits; conditional E-value: 5.4e-06 Beta-prop_CAF1B_HIR1 68 rhqkavnvvrfspsgelLasgdDesviiiWklke 101 h +v +vr+sp+gel asg++++++ +W+++ FUN_000935-T1 263 GHFGPVHCVRYSPDGELYASGSEDGTLRLWQHTV 296 57889*************************9875 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.1 7e-08 3.6e-05 21 112 .. 26 119 .. 18 122 .. 0.81 2 ! 17.9 0.0 3.1e-06 0.0016 11 87 .. 99 177 .. 94 230 .. 0.79 3 ! 25.4 0.0 1.6e-08 8.3e-06 32 82 .. 245 295 .. 224 311 .. 0.84 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 7e-08 Beta-prop_IFT122_1st 21 pdgtqlilaag.srllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtskl.egilkythndaiqcvsynpithql 107 p g li a+ + ++ + g + ++ghk +v+ + kd + a+g+ad s +w + + l h+ ++ v + p hql FUN_000935-T1 26 PHGYFLISACKdGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSgDEELTLPHKHIVKIVDFSPNGHQL 114 66666666653134455556668889999*******************************874315578899***************** PP Beta-prop_IFT122_1st 108 ascss 112 ++s+ FUN_000935-T1 115 LTASN 119 98875 PP == domain 2 score: 17.9 bits; conditional E-value: 3.1e-06 Beta-prop_IFT122_1st 11 ehcindiafkpdgtqlilaagsrll.vydtsdg.tllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegil 87 +h ++ + f p+g ql+ a+ +l+ ++d + + + lkg+ + + ++kd k + sg dk++ +w ++ + FUN_000935-T1 99 KHIVKIVDFSPNGHQLLTASNEKLMrIFDLQNEnAEPDLLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEV 177 68899999*************9997578976651556779*******************************87654433 PP == domain 3 score: 25.4 bits; conditional E-value: 1.6e-08 Beta-prop_IFT122_1st 32 srllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsk 82 +l +d +dg l+ kgh v+cv y+ dg+ +asgs d ++ +w FUN_000935-T1 245 FKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQHT 295 367889***************************************999754 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 1 5.2e+02 86 101 .. 24 39 .. 8 46 .. 0.75 2 ! 12.3 0.0 0.0002 0.1 216 291 .] 93 170 .. 84 170 .. 0.88 3 ! 12.9 0.0 0.00013 0.067 212 256 .. 172 217 .. 170 221 .. 0.86 4 ! 38.9 0.0 1.5e-12 7.8e-10 9 120 .. 197 308 .. 190 316 .. 0.89 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1 Beta-prop_WDR90_POC16_2nd 86 fspdgeylysacslGs 101 ++p+g +l sac+ G+ FUN_000935-T1 24 ITPHGYFLISACKDGK 39 4699********9996 PP == domain 2 score: 12.3 bits; conditional E-value: 0.0002 Beta-prop_WDR90_POC16_2nd 216 evsevhrsacsslavsedarylltag.dkvikvwdysmkldinfqvfiGhsekvqqvaftpdqqevlsvGd..aiflWd 291 e++ h++ + ++ s +++ llta+ +k+++++d + + + + + G++ ++++ ++ d++ v s G+ a+ lWd FUN_000935-T1 93 ELTLPHKHIVKIVDFSPNGHQLLTASnEKLMRIFDLQNE-NAEPDLLKGYTVNIRAALWSKDSKFVFSGGEdkAMRLWD 170 566679999999********99998736899****9865.678999************************866899998 PP == domain 3 score: 12.9 bits; conditional E-value: 0.00013 Beta-prop_WDR90_POC16_2nd 212 rllrevsevh.rsacsslavsedarylltagdkvikvwdysmkldi 256 r+++ev++v ++++ss+ +s+d++ l+++ k+i wd ++ ++ FUN_000935-T1 172 RTMSEVKKVDlPNSVSSMVLSKDGSVLVVSYAKTISFWDTERMENM 217 67899999964799*************************9876655 PP == domain 4 score: 38.9 bits; conditional E-value: 1.5e-12 Beta-prop_WDR90_POC16_2nd 9 latvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgey 92 + vs +ti Wd++ ++ + f+a++++ +a + hP+k++f++G ++ + f+ ++ + l +k h g v + +spdge+ FUN_000935-T1 197 VLVVSYAKTISFWDTERMENMKSFEAPTDIFSA-SLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGEL 279 557999***********************9765.89***********************************************9 PP Beta-prop_WDR90_POC16_2nd 93 lysacslGslalydase.eeyevlrvlgn 120 s ++ G+l l++ + ++y + r + n FUN_000935-T1 280 YASGSEDGTLRLWQHTVgKTYGLWRAVNN 308 999999******98764156666676665 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 2 1e+03 108 135 .. 10 41 .. 4 93 .. 0.63 2 ! 34.3 0.0 3.8e-11 2e-08 105 221 .. 94 210 .. 77 236 .. 0.86 3 ! 11.5 0.0 0.00033 0.17 109 157 .. 264 311 .. 255 314 .. 0.88 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2 Beta-prop_Aladin 108 pgh.spvtsvaWs...pkGdlLvsaspvdtsi 135 +gh +pv+ +++s p+G L+sa++ + + FUN_000935-T1 10 SGHtRPVVHLSFSditPHGYFLISACKDGKPM 41 55524888887754448899999887644433 PP == domain 2 score: 34.3 bits; conditional E-value: 3.8e-11 Beta-prop_Aladin 105 LkrpghspvtsvaWspkGdlLvsaspvdtsilvWdvaketavp.LrrvggggvsllkwspdgskllaatpssvfrvwetetWtcerWtvlkgr 196 L+ p+ + v v +sp+G+ L++as ++ + ++d ++e+a p L + + ++ + ws d + ++++ + +r+w+t+t + + l FUN_000935-T1 94 LTLPHKHIVKIVDFSPNGHQLLTASN-EKLMRIFDLQNENAEPdLLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNS 185 5556666788999***********96.678**********99868888889999*****************************9999****** PP Beta-prop_Aladin 197 vqaacwspdgsvllfateeepviys 221 v + s dgsvl+++ ++ + FUN_000935-T1 186 VSSMVLSKDGSVLVVSYAKTISFWD 210 *************999887665555 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00033 Beta-prop_Aladin 109 ghspvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvs 157 ++ pv +v +sp+G+l +s+s d ++ +W+ ++ L r+ ++g++ FUN_000935-T1 264 HFGPVHCVRYSPDGELYASGSE-DGTLRLWQHTVGKTYGLWRAVNNGIT 311 467***************9995.899****************9999986 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0062 3.2 278 340 .. 24 86 .. 17 87 .. 0.93 2 ? 5.1 0.0 0.026 13 85 119 .. 96 130 .. 87 138 .. 0.77 3 ? 5.9 0.0 0.014 7.3 90 128 .. 144 182 .. 129 191 .. 0.86 4 ! 22.6 0.0 1.2e-07 6.1e-05 18 117 .. 192 294 .. 183 301 .. 0.74 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0062 WD40_MABP1-WDR62_2nd 278 lDpsglyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhlisvsgDsCifvWr 340 + p g ++ ++c d + ++ + +G+ ++t Gh v + +d+ + + ++D vW+ FUN_000935-T1 24 ITPHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWN 86 56899*******************************************999999999888885 PP == domain 2 score: 5.1 bits; conditional E-value: 0.026 WD40_MABP1-WDR62_2nd 85 ldsknGvRvlkvspdgkhlasGDrsGniriydlet 119 l +k+ v+++ +sp+g++l + + +ri+dl++ FUN_000935-T1 96 LPHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQN 130 55677788888888888888888888888888886 PP == domain 3 score: 5.9 bits; conditional E-value: 0.014 WD40_MABP1-WDR62_2nd 90 GvRvlkvspdgkhlasGDrsGniriydletleellkiea 128 +R+ s+d+k + sG +r++d +t++e+ k++ FUN_000935-T1 144 NIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDL 182 58899999**************************99986 PP == domain 4 score: 22.6 bits; conditional E-value: 1.2e-07 WD40_MABP1-WDR62_2nd 18 lpagsFltcssDdtiRlWnleek.sseetalkrniysnell..kvlyvdeelsa.lkdvelaasekkdeseldsknG.vRvlkvspdgk 101 gs l +s +ti +W +e+ ++++ ++ +i+s l+ k +v ++ l + ++ ++ k+ ++++++ G v +++ spdg+ FUN_000935-T1 192 SKDGSVLVVSYAKTISFWDTERMeNMKSFEAPTDIFSASLHptKSCFVAGGDDFkLYKFDY--TDGKELESYKGHFGpVHCVRYSPDGE 278 467999**************9751456667899******9733667776554440444444..444455556666666*********** PP WD40_MABP1-WDR62_2nd 102 hlasGDrsGniriydl 117 asG G++r+++ FUN_000935-T1 279 LYASGSEDGTLRLWQH 294 ************9975 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.0077 4 6 101 .. 55 133 .. 53 164 .. 0.73 2 ! 35.7 0.0 1.7e-11 8.6e-09 40 186 .. 163 296 .. 151 312 .. 0.79 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0077 Beta-prop_EML 6 lgHtddikclavhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgek 101 gH+ + + +++++ + atG + ++W++ + l +++ v ++Fs +g++L++ sne+ + ++d q+++ FUN_000935-T1 55 EGHKGAVWSATLNKDATKAATGAAD----------FSAKVWNALSGDEELTL---PHKHIVKIVDFSP--NGHQLLT--ASNEKLMRIFDLQNENA 133 6899999999999999999999864..........34579999998877766...478889999***6..5667664..57788999999999864 PP == domain 2 score: 35.7 bits; conditional E-value: 1.7e-11 Beta-prop_EML 40 kphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhiaF 135 + + r Wd++t++ ++ + ++ ++vs++ sk +g++L++ +++s+Wd ++ e++ + ++ +d +++++ hp+ k+++v G + FUN_000935-T1 163 DKAMRLWDTRTMSEVKKV---DLPNSVSSMVLSK--DGSVLVVS---YAKTISFWDTERMENMKSFEAPTD-IFSASLHPT-KSCFVAGGD-DFKL 247 45789*****99887765...789*********7..68888874...4568*********99999887765.99******8.577887775.4555 PP Beta-prop_EML 136 Wtl...egkklekkkgifeksekpkyvlclafsengdvi.tGdsnGnilvWskgt 186 +++ +gk+le+ kg f+ v+c+ +s++g+++ +G ++G++ +W+++ FUN_000935-T1 248 YKFdytDGKELESYKGHFGP------VHCVRYSPDGELYaSGSEDGTLRLWQHTV 296 5542226889********95......9**********865999********9753 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.068 35 40 81 .. 15 59 .. 7 68 .. 0.80 2 ? 5.9 0.0 0.043 22 36 70 .. 97 131 .. 81 137 .. 0.77 3 ? 6.5 0.0 0.027 14 39 84 .. 143 187 .. 137 190 .. 0.87 4 ? 6.0 0.0 0.04 21 39 81 .. 184 225 .. 181 232 .. 0.85 5 ! 12.9 0.0 0.00027 0.14 39 78 .. 266 305 .. 246 312 .. 0.85 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.068 ANAPC4_WD40 40 evtslaWk...pdGklLavaysdgevrlldvesgklvhslsaksd 81 v +l+++ p+G +L+ a++dg+ l + +g+ + +++ ++ FUN_000935-T1 15 PVVHLSFSditPHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKG 59 5666666433389*********************99999987776 PP == domain 2 score: 5.9 bits; conditional E-value: 0.043 ANAPC4_WD40 36 kedsevtslaWkpdGklLavaysdgevrlldvesg 70 ++ v+ + ++p+G+ L a ++ +r++d ++ FUN_000935-T1 97 PHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNE 131 4567788999*********************9886 PP == domain 3 score: 6.5 bits; conditional E-value: 0.027 ANAPC4_WD40 39 sevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdkit 84 ++++ W++d k+ + +d +rl d + v++++ ++ ++ FUN_000935-T1 143 VNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNS-VS 187 5789999**************************9999988776.55 PP == domain 4 score: 6.0 bits; conditional E-value: 0.04 ANAPC4_WD40 39 sevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksd 81 ++v+s+ ++dG +L+v+y++ ++++ d e + ++s++a +d FUN_000935-T1 184 NSVSSMVLSKDGSVLVVSYAK-TISFWDTERMENMKSFEAPTD 225 57999999***********98.689999999998888887665 PP == domain 5 score: 12.9 bits; conditional E-value: 0.00027 ANAPC4_WD40 39 sevtslaWkpdGklLavaysdgevrlldvesgklvhslsa 78 + v++++++pdG+l a + +dg++rl + gk+ ++a FUN_000935-T1 266 GPVHCVRYSPDGELYASGSEDGTLRLWQHTVGKTYGLWRA 305 6799************************999998766665 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.6 0.0 0.005 2.5 88 165 .. 12 94 .. 3 96 .. 0.78 2 ! 10.3 0.0 0.00073 0.37 249 305 .. 67 123 .. 62 131 .. 0.66 3 ? 1.7 0.0 0.32 1.6e+02 70 111 .. 122 164 .. 113 177 .. 0.75 4 ? 2.8 0.0 0.15 75 225 261 .. 168 204 .. 147 222 .. 0.62 5 ! 15.4 0.0 2.1e-05 0.011 196 302 .. 181 286 .. 169 297 .. 0.81 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.005 WDR90_beta-prop_4th 88 havaltaiays...adGqtilsgdkdGlvavssprtGvtlrvlsdhkGapitviqstskeyedfGve..gaelwlaassdrrv 165 h+ ++ +++s +G ++s+ kdG + + tG + ++ hkGa ++ + G+ a++w a s+d+ + FUN_000935-T1 12 HTRPVVHLSFSditPHGYFLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWSATLNKDATKAATGAAdfSAKVWNALSGDEEL 94 5555566666522247999******************************9998777766666666642358999999999865 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00073 WDR90_beta-prop_4th 249 spkarlvavGfaerllrlvdcasgtaqdfaghddsvqlcrfspsgkllftaayseil 305 a+ a G a+ ++ ++ sg+++ h+ v++ fsp g+ l+ta+ ++++ FUN_000935-T1 67 NKDATKAATGAADFSAKVWNALSGDEELTLPHKHIVKIVDFSPNGHQLLTASNEKLM 123 455555666667777777777777777777777777777777777777777766554 PP == domain 3 score: 1.7 bits; conditional E-value: 0.32 WDR90_beta-prop_4th 70 tlrvfsisrtemelk.lhphavaltaiaysadGqtilsgdkdG 111 +r+f + + + e l+ ++v + a +s d + ++sg+ d FUN_000935-T1 122 LMRIFDLQNENAEPDlLKGYTVNIRAALWSKDSKFVFSGGEDK 164 5788888888887662467888899999999999999988775 PP == domain 4 score: 2.8 bits; conditional E-value: 0.15 WDR90_beta-prop_4th 225 fyslrkkqvvekiplpffavslslspkarlvavGfae 261 ++ r v+k+ lp s+ ls ++++v +a+ FUN_000935-T1 168 LWDTRTMSEVKKVDLPNSVSSMVLSKDGSVLVVSYAK 204 3444444456666777766777777666666666655 PP == domain 5 score: 15.4 bits; conditional E-value: 2.1e-05 WDR90_beta-prop_4th 196 slppslaafcpwdkallvyvGlGvkkevlfyslrkkqvvekiplpffavslslsp.karlvavGfaerllrlvdcasgtaqdfaghddsv 284 lp+s++++ +++ + +v + k ++f+ ++ + ++ p s sl p k+++va G + +l ++ + ++ + ++gh v FUN_000935-T1 181 DLPNSVSSMVLSKDGSVLVVSY--AKTISFWDTERMENMKSFEAPTDIFSASLHPtKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPV 268 5788888777666666666665..57899999999999999999999999999874689999999999***99999************** PP WDR90_beta-prop_4th 285 qlcrfspsgkllftaays 302 + r+sp g+l + + + FUN_000935-T1 269 HCVRYSPDGELYASGSED 286 *********998776654 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.073 37 113 155 .. 47 89 .. 24 95 .. 0.83 2 ? -0.3 0.0 1.1 5.4e+02 123 157 .. 98 132 .. 93 148 .. 0.86 3 ! 8.1 0.3 0.0028 1.4 109 160 .. 166 218 .. 141 244 .. 0.74 4 ! 15.8 0.0 1.3e-05 0.0066 109 155 .. 250 296 .. 219 308 .. 0.81 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.073 NBCH_WD40 113 dGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlr 155 G+ + + hk v + ++ d + atG+ d + vw++l FUN_000935-T1 47 TGDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALS 89 5677778888999999999999999999999999999999875 PP == domain 2 score: -0.3 bits; conditional E-value: 1.1 NBCH_WD40 123 hkdvvscvavtsdgsvlatGsydttvmvwevlrar 157 hk +v v + +g l t s + + ++++++ + FUN_000935-T1 98 HKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNEN 132 9********************99999898877655 PP == domain 3 score: 8.1 bits; conditional E-value: 0.0028 NBCH_WD40 109 islsdGrlvqsirqhk..dvvscvavtsdgsvlatGsydttvmvwevlrarsse 160 + l d r + ++++ + vs++ ++ dgsvl+ sy t+ w++ r+++++ FUN_000935-T1 166 MRLWDTRTMSEVKKVDlpNSVSSMVLSKDGSVLVV-SYAKTISFWDTERMENMK 218 4555666666665542226799999*******986.9*********99887654 PP == domain 4 score: 15.8 bits; conditional E-value: 1.3e-05 NBCH_WD40 109 islsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlr 155 +dG+ ++s + h v cv + dg++ a+Gs d t+ +w+ + FUN_000935-T1 250 FDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQHTV 296 3568***************************************9765 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.0 0.00047 0.24 197 266 .. 72 138 .. 53 156 .. 0.79 2 ? 5.6 0.0 0.024 12 47 95 .. 153 199 .. 137 218 .. 0.77 3 ! 11.0 0.0 0.00053 0.27 178 212 .. 260 294 .. 244 302 .. 0.69 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00047 Beta-prop_WDR75_1st 197 ciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnllsGGvesvlvqwryeeenk.kdfl 266 atG d ++w ++ +e t h+++v+ + f+p+G +ll+ e ++ + ++en d+l FUN_000935-T1 72 KAATGAADFSAKVWNALSGDEELTLP----HKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAePDLL 138 469********************986....66699****************99999888877666414555 PP == domain 2 score: 5.6 bits; conditional E-value: 0.024 Beta-prop_WDR75_1st 47 nhlqvyscsldgtvrlwdftdgiliktfvvgykilslyvsakhegvvfv 95 + v+s d ++rlwd +k + + ++ s+ s++ g+v+v FUN_000935-T1 153 DSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNSVSSMVLSKD--GSVLV 199 4556999999********999999999999999999998876..34433 PP == domain 3 score: 11.0 bits; conditional E-value: 0.00053 Beta-prop_WDR75_1st 178 dkkGaknaftcvachpkddciatGhedGkirlwrn 212 + kG + cv p+ + a+G edG +rlw+ FUN_000935-T1 260 SYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQH 294 45666666777777888888888888888888864 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.016 8.1 87 125 .. 85 122 .. 73 131 .. 0.65 2 ? 5.3 0.1 0.018 9.3 263 310 .. 173 217 .. 164 221 .. 0.76 3 ! 15.5 0.0 1.5e-05 0.0076 62 130 .. 225 293 .. 218 299 .. 0.92 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.016 Beta-prop_IFT140_1st 87 lneqdkeltelpklhkaeitvlewssngsrLvsgdksGv 125 +n +++ el+ hk+ ++++++s ng +L+++ ++ + FUN_000935-T1 85 WNALSGDE-ELTLPHKHIVKIVDFSPNGHQLLTASNEKL 122 55555443.444557777888888888888887766544 PP == domain 2 score: 5.3 bits; conditional E-value: 0.018 Beta-prop_IFT140_1st 263 eaeevlkvKLsgktgkeadiiwaekglLitatgesvirlwdlerddny 310 +++ev kv L ++ +++ ++g +++++ ++i +wd er +n+ FUN_000935-T1 173 TMSEVKKVDLPNSVSS---MVLSKDGSVLVVSYAKTISFWDTERMENM 217 5678888888777654...56666666666777899**********97 PP == domain 3 score: 15.5 bits; conditional E-value: 1.5e-05 Beta-prop_IFT140_1st 62 qvtvlsWHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWk 130 + s HPtk++ + g ++ ++ + +d++ e k h ++++++s g+ +sg + G+l +W+ FUN_000935-T1 225 DIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQ 293 5567788*************************************************************8 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 2.7 1.4e+03 14 52 .. 30 69 .. 22 85 .. 0.68 2 ? -0.2 0.0 2.9 1.5e+03 8 31 .. 107 130 .. 100 133 .. 0.75 3 ! 8.7 0.0 0.0047 2.4 13 36 .. 155 178 .. 148 192 .. 0.84 4 ? 7.6 0.0 0.01 5.2 12 63 .. 194 243 .. 183 252 .. 0.69 5 ? 6.9 0.0 0.017 8.8 15 38 .. 280 303 .. 264 308 .. 0.84 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2.7 Beta-prop_TEP1_C 14 liisAseDrtvKlWdretkkqvGlFvC.eapvlvlevnpn 52 +isA +D + l + +t +G F +++v++ ++n+ FUN_000935-T1 30 FLISACKDGKPMLRQGDTGDWIGTFEGhKGAVWSATLNKD 69 5788888888888888888888888752466666665543 PP == domain 2 score: -0.2 bits; conditional E-value: 2.9 Beta-prop_TEP1_C 8 lkltddliisAseDrtvKlWdret 31 + + +++As+++ +++ d ++ FUN_000935-T1 107 FSPNGHQLLTASNEKLMRIFDLQN 130 555667899******999999776 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0047 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdretkkqvG 36 + ++s eD++++lWd++t+ v FUN_000935-T1 155 KFVFSGGEDKAMRLWDTRTMSEVK 178 578999*************98875 PP == domain 4 score: 7.6 bits; conditional E-value: 0.01 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkkqvGlFvCeapvlvlevnpnpeseleLvcgD 63 d ++ s+ +t+ +Wd+e + + F ap +++++ +p+++ ++ gD FUN_000935-T1 194 DGSVLVVSYAKTISFWDTERMENMKSFE--APTDIFSASLHPTKSCFVAGGD 243 44677889***************99995..6666666666666555444444 PP == domain 5 score: 6.9 bits; conditional E-value: 0.017 Beta-prop_TEP1_C 15 iisAseDrtvKlWdretkkqvGlF 38 s seD t++lW+++ k Gl+ FUN_000935-T1 280 YASGSEDGTLRLWQHTVGKTYGLW 303 5699***********999999886 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.82 4.2e+02 341 377 .. 53 90 .. 42 103 .. 0.76 2 ! 15.6 0.0 1.5e-05 0.0078 318 414 .. 113 211 .. 95 232 .. 0.78 3 ! 7.3 0.0 0.0047 2.4 318 377 .. 237 297 .. 223 312 .. 0.87 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.82 Beta-prop_SCAP 341 tlqGhsGgitavyidqtmv.lasGGqdGaiclwdvltG 377 t++Gh G++ + +++ a+G d + +w+ l+G FUN_000935-T1 53 TFEGHKGAVWSATLNKDATkAATGAADFSAKVWNALSG 90 77899999887777655441566778888888888887 PP == domain 2 score: 15.6 bits; conditional E-value: 1.5e-05 Beta-prop_SCAP 318 rvvtGsqdhtvrvyrledsccl.ftlqGhsGgit.avyidqtmvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvctt.scvissGlddli 409 +++t s + +r++ l++ l+G++ i a++ ++ + sGG d a+ lwd t s v +v v+s+v + v+ i FUN_000935-T1 113 QLLTASNEKLMRIFDLQNENAEpDLLKGYTVNIRaALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDL-PNSVSSMVLSKdGSVLVVSYAKTI 206 68999999*******987766515689***9996257788888999*******************99865.456777776542567777788899 PP Beta-prop_SCAP 410 siwdr 414 s wd FUN_000935-T1 207 SFWDT 211 99984 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0047 Beta-prop_SCAP 318 rvvtGsqdhtvrvyrledscclftlqGhsGgitav.yidqtmvlasGGqdGaiclwdvltG 377 v+G d + + d l + +Gh G + +v y + + asG dG++ lw G FUN_000935-T1 237 CFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVrYSPDGELYASGSEDGTLRLWQHTVG 297 57899999999999999***************99978889999*************87666 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 1.2e-07 5.9e-05 41 160 .. 102 218 .. 90 232 .. 0.85 2 ? -1.0 0.0 2.3 1.2e+03 72 99 .. 255 282 .. 237 297 .. 0.63 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 1.2e-07 WD40_MABP1-WDR62_1st 41 lsalafspdGkylvtGesghlpavrvwdvaeksqvael.qkhkygvacvafspnekyivsvgyqhdmvvnvwdwkkdvvvaankvsskv 128 + + fsp+G+ l+t + +r++d++++ +l +++ + s+++k++ s g d+ + +wd + + v + v FUN_000935-T1 102 VKIVDFSPNGHQLLTASNE--KLMRIFDLQNENAEPDLlKGYTVNIRAALWSKDSKFVFSGGE--DKAMRLWDTRTMSEVKKVDLPNSV 186 55678**********8876..679*****9887766651667778888899*********997..566789*****9999999999*** PP WD40_MABP1-WDR62_1st 129 tavsfsedssyfvtvGnrhvkfwyldaskekk 160 ++ +s+d+s +v + + fw ++ ++ k FUN_000935-T1 187 SSMVLSKDGSVLVVSYAKTISFWDTERMENMK 218 ***********************998887766 PP == domain 2 score: -1.0 bits; conditional E-value: 2.3 WD40_MABP1-WDR62_1st 72 ksqvaelqkhkygvacvafspnekyivs 99 +++ ++h v+cv +sp+ + s FUN_000935-T1 255 GKELESYKGHFGPVHCVRYSPDGELYAS 282 5555555666556777777777665444 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 4.8e-05 0.024 211 277 .. 96 161 .. 77 162 .. 0.86 2 ? 6.1 0.0 0.017 8.8 133 244 .. 189 294 .. 171 304 .. 0.66 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 4.8e-05 Beta-prop_RIG_2nd 211 saekasitsvkwsnansnlllsfsidgkvkvWdleepek.eeltitykcpmlcglFlPtdenivlcgG 277 ++k+ ++ v +s++ ++ll+ s + +++ dl++++ + l++ y+ + ++l++ d ++v +gG FUN_000935-T1 96 LPHKHIVKIVDFSPNG-HQLLTASNEKLMRIFDLQNENAePDLLKGYTVNIRAALWS-KDSKFVFSGG 161 579999*******976.778899***********99987478**************8.7888999888 PP == domain 2 score: 6.1 bits; conditional E-value: 0.017 Beta-prop_RIG_2nd 133 lvgtedGalqllerkkelekayskllkqealls.ryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkws 223 +v ++dG++ +++ +k+ + ++ + ++e++ s + tdi l+ +k va + ++f+ +++++ ++ + +++v++s FUN_000935-T1 189 MVLSKDGSVLVVSYAKTIS-FWDT-ERMENMKSfEAPTDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKE----LESYKGHFGPVHCVRYS 274 5667778877777777765.5553.4555554447777877777777777777777777777777555543....34567788888888888 PP Beta-prop_RIG_2nd 224 nansnlllsfsidgkvkvWdl 244 + + l s s dg++++W+ FUN_000935-T1 275 PDGE-LYASGSEDGTLRLWQH 294 8765.6677788888888875 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 6.5e-08 3.3e-05 101 214 .. 151 264 .. 95 308 .. 0.64 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 6.5e-08 Beta-prop_ACSF4 101 dsesglvvvgsydknlyaldvesgklvwklklggsifsspllskskesvlvatldGtvaalseesgeilWkvklesPiFsspvilsde.vvvae 193 ++s++v+ g dk ++ +d+++ + v k++l +s+ s l ++ svlv + ++t++ ++e+ e + ++++ iFs +++ +v + FUN_000935-T1 151 SKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNSVSSMVLS--KDGSVLVVSYAKTISFWDTERMENMKSFEAPTDIFSASLHPTKScFVAGG 242 445556666677777777777777777777776666554443..46666666777777777777777777777777777666664444144444 PP Beta-prop_ACSF4 194 vdgtvlcls.eegeklwsvktk 214 d ++++++ ++g++l s+k + FUN_000935-T1 243 DDFKLYKFDyTDGKELESYKGH 264 4556677765556666666643 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.0 0.0038 1.9 321 379 .. 76 136 .. 56 141 .. 0.70 2 ? 4.7 0.2 0.031 16 152 185 .. 151 185 .. 137 219 .. 0.56 3 ? 2.8 0.0 0.12 60 140 184 .. 181 224 .. 156 240 .. 0.55 4 ! 6.6 0.0 0.0085 4.3 149 194 .. 230 275 .. 204 284 .. 0.81 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0038 Beta-prop_SPT8 321 cveefdlk..mpskpkstlklpsisGpvsavkslpnekhlliaskdn.irlydleksskipf 379 +f+ k + + l lp v v pn+++ll as++ +r++dl++ + p FUN_000935-T1 76 GAADFSAKvwNALSGDEELTLPHK-HIVKIVDFSPNGHQLLTASNEKlMRIFDLQNENAEPD 136 455666662233445667788865.47999999***********98746*****99888775 PP == domain 2 score: 4.7 bits; conditional E-value: 0.031 Beta-prop_SPT8 152 stedkfl.sgswdkkilewdlntgkvineykgats 185 s++ kf+ sg+ dk + wd +t + +++ + +s FUN_000935-T1 151 SKDSKFVfSGGEDKAMRLWDTRTMSEVKKVDLPNS 185 33333322444444444444444444444443333 PP == domain 3 score: 2.8 bits; conditional E-value: 0.12 Beta-prop_SPT8 140 khsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgat 184 + n v+ + l+ ++ +l s+ k i wd + + ++++++ t FUN_000935-T1 181 DLPNSVSSMVLS-KDGSVLVVSYAKTISFWDTERMENMKSFEAPT 224 333444444443.33456666666666667766666666666555 PP == domain 4 score: 6.6 bits; conditional E-value: 0.0085 Beta-prop_SPT8 149 rlnstedkflsgswdkkilewdlntgkvineykgatselsalelrp 194 l t+ f++g+ d k++++d gk ++ykg+ + + ++ + p FUN_000935-T1 230 SLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSP 275 466677889***************************9999999887 PP >> Beta-prop_IP5PC_F IP5P C-F beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.1 0.002 1 52 150 .. 131 222 .. 114 237 .. 0.81 2 ! 12.3 0.0 0.00015 0.077 97 144 .. 251 298 .. 243 307 .. 0.83 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.002 Beta-prop_IP5PC_F 52 edaapfaesastsptlclvvdegsklvwsGhkdGkirswkmdqssddtsfkeglswqahrgpvlslvissyGdlwsgsegGvikvwpwesie 143 e+a p t ++ + + sk+v+sG d +r w + ++s+ + l +v s+v+s G + s + +i w e +e FUN_000935-T1 131 ENAEPDLLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKK--VDL-----PNSVSSMVLSKDGSVLVVSYAKTISFWDTERME 215 66666666677777888888999****************8877655433..333.....568999**********************99999 PP Beta-prop_IP5PC_F 144 kslslsa 150 s++a FUN_000935-T1 216 NMKSFEA 222 8777665 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00015 Beta-prop_IP5PC_F 97 ddtsfkeglswqahrgpvlslvissyGdlw.sgsegGvikvwpwesiek 144 d t ke s++ h gpv ++ s G+l+ sgse+G++++w ++ k FUN_000935-T1 251 DYTDGKELESYKGHFGPVHCVRYSPDGELYaSGSEDGTLRLWQH-TVGK 298 556678999********************9679*********85.5555 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 6.5e-05 0.033 203 280 .] 98 169 .. 42 169 .. 0.86 2 ! 7.0 0.0 0.0095 4.8 164 202 .. 147 184 .. 138 238 .. 0.66 3 ? 6.5 0.0 0.013 6.9 171 280 .] 195 292 .. 187 292 .. 0.76 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 6.5e-05 Beta-prop_EIPR1 203 gfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 + v+ vdf+p ++llta ++ + i+D+ ++ lk+ + ++++l+ ++ +++ s++ d++++Lw FUN_000935-T1 98 HKHIVKIVDFSPN-GHQLLTASNEKLMRIFDLQ----NENAEPDLLKGYTVNIRAALW-SKDSKFVFSGGEDKAMRLW 169 4568999***995.689****************....77788899*****99998877.67789************** PP == domain 2 score: 7.0 bits; conditional E-value: 0.0095 Beta-prop_EIPR1 164 aAldphdsslvlvace.sglqliDlRakkkksvanvetlh 202 aAl ds+ v +e + + l+D+R++++++ v+ FUN_000935-T1 147 AALWSKDSKFVFSGGEdKAMRLWDTRTMSEVK--KVDLPN 184 7888899999999999999*********9887..444433 PP == domain 3 score: 6.5 bits; conditional E-value: 0.013 Beta-prop_EIPR1 171 sslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfy 264 s+ +v+ + ++++D+ ++++ + + e+ + + +p+ k +++ gdd ++ +D dg+ +l+ k+h v+ v++ p FUN_000935-T1 195 GSVLVVSYAKTISFWDTERMENMK--SFEAPT---DIFSASLHPT-KSCFVAGGDDFKLYKFDYT-DGK----ELESYKGHFGPVHCVRYSPD- 276 566677777888899988887777..444444...3444455554.46799999**999999998.555....56777889899999999997. PP Beta-prop_EIPR1 265 deLilscssdstlkLw 280 eL s+s d tl+Lw FUN_000935-T1 277 GELYASGSEDGTLRLW 292 68*************9 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.12 64 65 107 .. 57 107 .. 51 122 .. 0.78 2 ! 11.5 0.0 0.00029 0.15 66 104 .. 183 220 .. 171 232 .. 0.83 3 ? 2.5 0.0 0.16 80 65 100 .. 264 299 .. 249 312 .. 0.87 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.12 Beta-prop_VPS8 65 eqgaVsalafnadstrllaGyarGqilmwDlsng........kllrtisda 107 ++gaV + ++n+d t+ ++G a+ + +w+ +g k + +i d FUN_000935-T1 57 HKGAVWSATLNKDATKAATGAADFSAKVWNALSGdeeltlphKHIVKIVDF 107 78****************************999955555555555555555 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00029 Beta-prop_VPS8 66 qgaVsalafnadstrllaGyarGqilmwDlsngkllrti 104 +Vs++ +++d++ l++ ya+ +i wD+++ + +++ FUN_000935-T1 183 PNSVSSMVLSKDGSVLVVSYAK-TISFWDTERMENMKSF 220 569******************9.7******998777665 PP == domain 3 score: 2.5 bits; conditional E-value: 0.16 Beta-prop_VPS8 65 eqgaVsalafnadstrllaGyarGqilmwDlsngkl 100 + g+V ++ + d+ + G ++G++++w + gk+ FUN_000935-T1 264 HFGPVHCVRYSPDGELYASGSEDGTLRLWQHTVGKT 299 679***************************999975 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.51 2.6e+02 258 315 .. 98 154 .. 81 159 .. 0.52 2 ! 18.1 0.0 3e-06 0.0015 4 150 .. 149 293 .. 146 300 .. 0.81 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.51 Beta-prop_WDR19_1st 258 hkdslsdialseslkkvascgdnt.vkihelsdlkevkeiieldeeekelekvewseDG 315 hk+ ++ + +s++ ++++++++++ ++i++l++ + + ++ + +++++ ws+D FUN_000935-T1 98 HKHIVKIVDFSPNGHQLLTASNEKlMRIFDLQNENAEPDLLKGYT--VNIRAALWSKDS 154 445555555555555555554433245555555444433333322..234444444443 PP == domain 2 score: 18.1 bits; conditional E-value: 3e-06 Beta-prop_WDR19_1st 4 aWqkksgnylavagknkvvkiyd.rqGelvdeiklkgkctaleWdkdgdlLaiiqeksslvllwdantkkt.skldtglkdkltfllWsk 91 W+k +++++ g++k ++++d r+ ++v++++l+++++++ +kdg++L + +++ +wd+++ + +++++ d +++ l FUN_000935-T1 149 LWSK-DSKFVFSGGEDKAMRLWDtRTMSEVKKVDLPNSVSSMVLSKDGSVLVVSYA--KTISFWDTERMENmKSFEA-PTDIFSASLH-P 233 5986.89***************9667789**********************99886..689****998654155655.4455555555.5 PP Beta-prop_WDR19_1st 92 kspiLavGtskGnlllYnkktskkipilGkHskkItcgawskenlL.algseDktltisn 150 +++ + G + +l+ ++ + k++ H + c +s ++ L a gseD tl + + FUN_000935-T1 234 TKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELyASGSEDGTLRLWQ 293 5555666777789999999999**999999**********97765438999999998765 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 4.3e-06 0.0022 61 154 .. 98 190 .. 83 194 .. 0.81 2 ? 0.1 0.0 1.1 5.6e+02 75 112 .. 194 231 .. 191 257 .. 0.57 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 4.3e-06 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsnt....vvqtYetdspvWsCcWseddsnylyaGlqnGsvlvfDiRqtssevselekeesrsp 152 H++ ++ + F++++++ ll+as k +++ +l++++ +++ Y+++ + Ws +ds+++++G ++ ++ ++D+R++s ev++++ ++s s+ FUN_000935-T1 98 HKHIVKIVDFSPNGHQ-LLTASNEKLMRIFDLQNENaepdLLKGYTVNIR--AALWS-KDSKFVFSGGEDKAMRLWDTRTMS-EVKKVDLPNSVSS 188 7777888899999655.78**************99734446999998654..56776.5778999**************765.7999999998877 PP WD40_RFWD3 153 vv 154 +v FUN_000935-T1 189 MV 190 66 PP == domain 2 score: 0.1 bits; conditional E-value: 1.1 WD40_RFWD3 75 dslllsaslDktlkltsllsntvvqtYetdspvWsCcW 112 d+ +l +s kt+ + + + ++++e+++++ s FUN_000935-T1 194 DGSVLVVSYAKTISFWDTERMENMKSFEAPTDIFSASL 231 45556666666666666666666666666666666554 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 3.6e-06 0.0018 36 263 .. 67 292 .. 51 295 .. 0.83 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 3.6e-06 Beta-prop_WDR36-Utp21_1st 36 dkdlvfaavgn.....kivvfkrgkevaellkeheekikkllvfgdhlvavdednsllvwkieteelyteiefseeefeitall 114 +kd + aa+g k++ g e +l ++h ki ++ + g++l+++++++ ++++++++e+ ++ + +i a l FUN_000935-T1 67 NKDATKAATGAadfsaKVWNALSGDEELTLPHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEPDLLKGY-TVNIRAAL 149 555555555543232278888888888888899999*****************999******9998887776554.55555554 PP Beta-prop_WDR36-Utp21_1st 115 hpsTYlnKilvgskqGslqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsi 198 s ++ g ++ +++lw+ rt + + +++ + +++++++ s +v+ +++a+ +i + + + e + ++++ + + s FUN_000935-T1 150 W-SKDSKFVFSGGEDKAMRLWDTRTMSEVKKVD-LPNSVSSMVLSKDGSVLVVSYAK-TISFWDTERMENMKSFEAP-TDIFSA 229 3.33344578899999*************9996.899******************99.9****************99.889999 PP Beta-prop_WDR36-Utp21_1st 199 sFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkew 263 s ++ +++g ++ +++ +d +++ ++ + + H g+v+++++ p+ +l + ++D +l+ w FUN_000935-T1 230 SLHPT-KSCFVAGGDDFKLYKFDYTDGKELESY-KGHFGPVHCVRYSPDGELYASGSEDGTLRLW 292 98765.77999999*************999999.5799*************************99 PP >> Tricorn_2nd Tricorn protease second beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.1 2.1e-05 0.011 42 149 .. 102 207 .. 79 225 .. 0.81 2 ! 6.9 0.0 0.0062 3.2 46 141 .. 190 281 .. 165 300 .. 0.76 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.1e-05 Tricorn_2nd 42 yrlvewlndgkrvaavsdeeeeeelvildadgsekaltdedlgrieelkvspdgkkiavannrneLllvdle.tgeatlidkseegaiedfswspd 136 ++v ++++g++++++s+ e+ +++ l+++++e+ l + +++i++ +s+d+k++ + + + + l d e++++d ++ ++++ s d FUN_000935-T1 102 VKIVDFSPNGHQLLTASN-EKLMRIFDLQNENAEPDLLKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRtMSEVKKVDLPNS--VSSMVLSKD 194 58999******9999998.66778888888888888************************9999999999886678888888776..899****** PP Tricorn_2nd 137 srwlAYsfpesne 149 ++ l+ s+ ++ + FUN_000935-T1 195 GSVLVVSYAKTIS 207 *999888775443 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0062 Tricorn_2nd 46 ewlndgkrvaavsdeeeeeelvildadgsekaltdedlgrieelkvspdgkkiavannrneLllvdletgeatlidkseegaiedfswspdsrwlA 141 ++dg+ v++vs+ +++ + d ++ e+ + e i++ ++ p+++ +++ + ++L+ d ++g+ k ++g ++ + +spd+++ A FUN_000935-T1 190 VLSKDGS-VLVVSY---AKTISFWDTERMENMKSFEAPTDIFSASLHPTKSCFVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYA 281 4567777.888888...6778888888887776666777889999999999999999999999999999999999999999999999999998766 PP >> B-prop_COPA_B_2nd COPA/B second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 3.9e-06 0.002 34 138 .. 103 215 .. 92 228 .. 0.82 2 ? -1.8 0.0 4.8 2.4e+03 44 82 .. 236 282 .. 214 297 .. 0.57 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 3.9e-06 B-prop_COPA_B_2nd 34 qslshnpngrfvlv.cgdgeyeiyt......alalrnkaygkgldfvwvarnrfAvlek.sktvkifknfkekktksikleysvekifgggt 117 + + ++png+ +l +++ + i+ + +l + + + +++w++ ++f++ +k +++ + ++ k+++l++sv++++ ++ FUN_000935-T1 103 KIVDFSPNGHQLLTaSNEKLMRIFDlqnenaEPDLLKGYTVNIRAALWSKDSKFVFSGGeDKAMRLWDTRTMSEVKKVDLPNSVSSMVLSKD 194 567788999888884334444455566677777777888889999***********9988999***8777888889**************** PP B-prop_COPA_B_2nd 118 GslLgvksessvilYDwqqkk 138 Gs+L+v+ ++++++D ++ + FUN_000935-T1 195 GSVLVVSYAKTISFWDTERME 215 ****************98766 PP == domain 2 score: -1.8 bits; conditional E-value: 4.8 B-prop_COPA_B_2nd 44 fvlvcgdgeyeiyt.......alalrnkaygkgldfvwvarnr.fAv 82 + v+g +++++y+ +l+ + +g +++ +++ ++ +A FUN_000935-T1 236 SCFVAGGDDFKLYKfdytdgkELESYKGHFGPVHCVRYSPDGElYAS 282 34456666677776666555555555555555555555553333444 PP >> Beta-prop_Vps41 Vps42 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.15 76 23 108 .. 25 112 .. 18 127 .. 0.80 2 ? 1.6 0.0 0.36 1.8e+02 74 120 .. 192 243 .. 153 252 .. 0.62 3 ! 11.5 0.0 0.00036 0.18 26 80 .. 235 290 .. 212 299 .. 0.82 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.15 Beta-prop_Vps41 23 lihekvlvfgthsGiihildpdg.ntirtfkahrasisslsidtdGeylAsaSmDGtvvigslseeee.iavdFkrpvkavaldpnys 108 + h +l+ + + G+ ++ + d+ + i tf+ h+ ++ s ++++d++ A+++ D + + + + +e + k vk+v +pn + FUN_000935-T1 25 TPHGYFLISACKDGKPMLRQGDTgDWIGTFEGHKGAVWSATLNKDATKAATGAADFSAKVWNALSGDEeLTLPHKHIVKIVDFSPNGH 112 5566777888888888887766438899***************************988887766555415678999999988888765 PP == domain 2 score: 1.6 bits; conditional E-value: 0.36 Beta-prop_Vps41 74 SmDGtvvigslseee........eiavdFkrpvkavaldpnysksssksfisGgk 120 S DG+v+++s + e++ F+ p+ + + + + +k f+ Gg+ FUN_000935-T1 192 SKDGSVLVVSYAKTIsfwdtermENMKSFEAPTDIFSASLHPTK---SCFVAGGD 243 66777777665433211111111233346666666665555543...24666665 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00036 Beta-prop_Vps41 26 ekvlvfgthsGiihild.pdgntirtfkahrasisslsidtdGeylAsaSmDGtvv 80 ++++v g + +++ +d +dg++++++k h +++++ + dGe As+S DGt+ FUN_000935-T1 235 KSCFVAGGDDFKLYKFDyTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLR 290 5667777777777777636899*******************************986 PP >> RMC1_N Regulator of MON1-CCZ1 complex, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.025 13 34 101 .. 94 158 .. 77 161 .. 0.84 2 ? 4.2 0.0 0.12 61 40 79 .. 184 222 .. 167 238 .. 0.81 3 ? 5.0 0.0 0.066 34 38 59 .. 264 285 .. 234 300 .. 0.78 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.025 RMC1_N 34 friedkgpvlsikfSlDkkilavqrssksvefinfaedetsveysqscksksakilgfvWtsnneivl 101 +++ +k v+ + fS++ + l ++k ++++++++ + + k+ + +i W++ + +v+ FUN_000935-T1 94 LTLPHKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQNENAEPDL---LKGYTVNIRAALWSKDSKFVF 158 56778999***************************998887766...555667888888888887776 PP == domain 2 score: 4.2 bits; conditional E-value: 0.12 RMC1_N 40 gpvlsikfSlDkkilavqrssksvefinfaedetsveysq 79 ++v s+ +S D ++l v +k++ f++++ e+++++ FUN_000935-T1 184 NSVSSMVLSKDGSVLVVSY-AKTISFWDTERMENMKSFEA 222 5799***********8875.6789***9998888777765 PP == domain 3 score: 5.0 bits; conditional E-value: 0.066 RMC1_N 38 dkgpvlsikfSlDkkilavqrs 59 + gpv+++++S+D ++ a + FUN_000935-T1 264 HFGPVHCVRYSPDGELYASGSE 285 569***********99886555 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.002 1 61 151 .. 101 186 .. 74 206 .. 0.78 2 ! 6.9 0.0 0.0089 4.6 32 90 .. 238 296 .. 226 303 .. 0.82 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.002 Beta-prop_HPS5 61 aistvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsvtklssskasalfkvsvqv 151 ++ v +sp+ + + a+++ l+ +++l+ +++++p +l + ++ a lW+++s+ v++G e ++ + + + ++ + ++++ +v FUN_000935-T1 101 IVKIVDFSPNGHQLLTASNEKLMRIFDLQ-NENAEPDLLKGYTV----NIRAALWSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLPNSV 186 4677899999999999************7.88899999987665....677889***********99999999988888766666666543 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0089 Beta-prop_HPS5 32 laLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelni 90 ++ G ++y f+ + k l+ + g++ +v spd +l a ++++g + ++++++ FUN_000935-T1 238 FVAGGDDFKLYKFDYTDGKELESYKGHFGPVHCVRYSPDGELYASGSEDGTLRLWQHTV 296 5556666667777777777788888888****************************985 PP >> Beta-prop_WDR75_2nd WD repeat-containing protein 75 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.48 2.5e+02 78 139 .. 80 132 .. 54 153 .. 0.71 2 ! 13.5 0.0 6.3e-05 0.032 163 198 .. 188 223 .. 182 237 .. 0.85 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.48 Beta-prop_WDR75_2nd 78 lqlklweydektqsfvlnttitaphedkitalcfseseesttllvtaskdgkfkvwllaeds 139 ++ k+w+ +++ + ++t ph++ ++ + fs++ + l+tas+++ ++++ l++++ FUN_000935-T1 80 FSAKVWN------ALSGDEELTLPHKHIVKIVDFSPNGH---QLLTASNEKLMRIFDLQNEN 132 4555553......34445567889999999999988877...78999999999998887765 PP == domain 2 score: 13.5 bits; conditional E-value: 6.3e-05 Beta-prop_WDR75_2nd 163 nccfsedgsllavsfeevvtvwesetwelkltlcqp 198 + +s+dgs+l vs+ ++++ w++e e + ++ p FUN_000935-T1 188 SMVLSKDGSVLVVSYAKTISFWDTERMENMKSFEAP 223 5678*********************99988887665 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.0 0.0013 0.67 98 190 .. 94 185 .. 77 193 .. 0.77 2 ! 9.0 0.0 0.0021 1.1 53 173 .. 179 291 .. 170 301 .. 0.78 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0013 Beta-prop_NUP159_NUP214 98 pafslstngvsiralkpnpspeaellailtsngkLlladlkarslv....svlkenvssfdwsnkgkqlvvgladgtaqqlkpadg 179 ++ ++ v+i+++ pn +++l+ ++++ ++++dl++++++ + + n+ ++ ws+ k ++ g +d+ + +++++ FUN_000935-T1 94 LTLPHKHI-VKIVDFSPN----GHQLLTASNEKLMRIFDLQNENAEpdllKGYTVNIRAALWSKDSKFVFSGGEDKAMRLWDTRTM 174 33333333.344444444....56999999999999********999888888999**************************9988 PP Beta-prop_NUP159_NUP214 180 evkaeiprpee 190 ++ ++++ p++ FUN_000935-T1 175 SEVKKVDLPNS 185 88889988887 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0021 Beta-prop_NUP159_NUP214 53 ektisvprvihvaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlk 138 + ++++ v+ ++ s+d+s+lv+ + +++ d+e +e + ++f+ +t+ i ++ ++p++ ++ ++ kL+ +d FUN_000935-T1 179 KVDLPN-SVSSMVLSKDGSVLVV--SYAKTISFWDTERME---NMKSFEAPTD---IFSASLHPTK--SCFVAGGDDFKLYKFDYT 253 334555.99*********96666..556689*********...6899999999...*********6..477778888899999988 PP Beta-prop_NUP159_NUP214 139 arslv...svlkenvssfdwsnkgkqlvvgladgtaqq 173 +++ + + v ++ s g+ + g++dgt+ FUN_000935-T1 254 DGKELesyKGHFGPVHCVRYSPDGELYASGSEDGTLRL 291 777554666666779*******************9654 PP >> DUF5074 Domain of unknown function (DUF5074) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 5.9e-05 0.03 107 235 .. 124 257 .. 107 266 .. 0.77 2 ? 2.6 0.0 0.2 1e+02 139 183 .. 238 285 .. 232 295 .. 0.77 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 5.9e-05 DUF5074 107 svlnletfe.vGkkiegvsggevgdlikte.kyifavssskgvlvidaekkkvvktie.vkgatsvvqakDGnvwaatets.lvkinpatlt.vkk 197 +++l++ + + ++g + +l+ + k +f + k + d + + vk+++ + + s+v++kDG+v ++ ++ ++ + ++ +k FUN_000935-T1 124 RIFDLQNENaEPDLLKGYTVNIRAALWSKDsKFVFSGGEDKAMRLWDTRTMSEVKKVDlPNSVSSMVLSKDGSVLVVSYAKtISFWDTERMEnMKS 219 5566666554456777777755667776542678888888899999999*********9999************99988776888999999999** PP DUF5074 198 idlpkdlsstsswgawtpgsltasakentlY..syssgkk 235 + p d ++s++ t++ + a+ + lY y+ gk+ FUN_000935-T1 220 FEAPTD--IFSASLHPTKSCFVAGGDDFKLYkfDYTDGKE 257 *****8..56666667777899999999999655566665 PP == domain 2 score: 2.6 bits; conditional E-value: 0.2 DUF5074 139 favsssk.gvlvidaekkkvvktie..vkgatsvvqakDGnvwaatet 183 f++ + + +++ d ++ k +++++ ++++ v ++DG+++a+ ++ FUN_000935-T1 238 FVAGGDDfKLYKFDYTDGKELESYKghFGPVHCVRYSPDGELYASGSE 285 56655555777777778777888877778999999*********9876 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.014 6.9 189 270 .. 151 225 .. 139 251 .. 0.72 2 ! 9.2 0.0 0.0014 0.73 65 140 .. 221 294 .. 211 307 .. 0.86 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.014 Beta-prop_DCAF12 189 saknqelgavsldGyfhlwkaentlsrllslrlpyarenvcltycdelslyavGsqshvsfldlrqekqnirplcsreggtg 270 s+ + + + d ++lw ++ t+s ++ + lp ++ l +++ s+ +v +sf d + +++ s e+ t+ FUN_000935-T1 151 SKDSKFVFSGGEDKAMRLWDTR-TMSEVKKVDLPNSVSSMVL--SKDGSVLVVSYAKTISFWDTERM----ENMKSFEAPTD 225 5555555555567788999875.8999******999888776..68999************998654....33444444444 PP == domain 2 score: 9.2 bits; conditional E-value: 0.0014 Beta-prop_DCAF12 65 qpasGihaielnpsktllatgGenpnslavyqlPtldPlclGdrkghkdwifaiawlsd.tvavsGsrdgtlalwrv 140 + ++ i + l p+k+ + +gG++ + +y++ d l kgh + ++ + d + sGs dgtl lw+ FUN_000935-T1 221 EAPTDIFSASLHPTKSCFVAGGDD---FKLYKFDYTDGKELESYKGHFGPVHCVRYSPDgELYASGSEDGTLRLWQH 294 566789999999***999999986...679**************************98845889***********85 PP >> Nucleoporin_N Nup133 N terminal like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.0052 2.7 202 248 .. 98 144 .. 80 171 .. 0.83 2 ? 3.1 0.0 0.086 44 79 168 .. 182 255 .. 153 262 .. 0.73 3 ? -0.4 0.0 1 5.2e+02 141 163 .. 269 294 .. 266 301 .. 0.72 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0052 Nucleoporin_N 202 reeivqlrvdssreerllytltskgtirvydls.pnggsslksdadir 248 +++iv+++ d s + ++l t+++++ +r++dl+ +n +++l + ++++ FUN_000935-T1 98 HKHIVKIV-DFSPNGHQLLTASNEKLMRIFDLQnENAEPDLLKGYTVN 144 56666664.44445699****************9999*****999886 PP == domain 2 score: 3.1 bits; conditional E-value: 0.086 Nucleoporin_N 79 llvkPkpgvfqedpgllLvvattgdivywesissaaslglstnelqlletdlsvlsdgevvtdlinaepaGriflagstgrlyeltyrds 168 l+ ++++ v + + g++Lvv+ +i +w + + +++ +e + d +++ ++++ ++++g++ +ly ++y+d FUN_000935-T1 182 LPNSVSSMVLS-KDGSVLVVSYAKTISFWDTERME--------NMKSFEAPT----D--IFSASLHPTKSC-FVAGGDDFKLYKFDYTDG 255 55666666665.66889999999999999855555........566666633....3..566677777788.777777778888888875 PP == domain 3 score: -0.4 bits; conditional E-value: 1 Nucleoporin_N 141 dlinaepaGriflagstg...rlyel 163 +++ + p+G+++++gs + rl++ FUN_000935-T1 269 HCVRYSPDGELYASGSEDgtlRLWQH 294 57778888888888887777777765 PP >> WD40_like WD40-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 1.7 8.8e+02 6 33 .. 105 132 .. 100 145 .. 0.85 2 ? 11.0 0.0 0.00056 0.29 8 108 .. 150 251 .. 140 285 .. 0.82 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.7 WD40_like 6 idlskkssliayGgkddkctlldlesle 33 +d+s+++ ++ ++++ ++++dl++++ FUN_000935-T1 105 VDFSPNGHQLLTASNEKLMRIFDLQNEN 132 8999999999999999999999998865 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00056 WD40_like 8 lskkssliayGgkddkctlldlesleevsiiesFsdsviyvkfldndlilvatlDGtileslleneeviseekieedi..sfveviddkiliGtnk 101 sk+s+++ Gg+d+ ++l d+++ ev+ ++ +sv + + ++ +lv++ ti+ + e+ e +++ + di + ++ ++ ++ G+ FUN_000935-T1 150 WSKDSKFVFSGGEDKAMRLWDTRTMSEVKKVD-LPNSVSSMVLSKDGSVLVVSYAKTISFWDTERMENMKSFEAPTDIfsASLHPTKSCFVAGGDD 244 489999***********************998.689**999999999***********99999999999999999999433457788889999999 PP WD40_like 102 Gsiylfs 108 ++y+f+ FUN_000935-T1 245 FKLYKFD 251 9999986 PP >> Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.00055 0.28 173 223 .. 142 186 .. 83 262 .. 0.78 2 ? -1.1 0.0 1.5 7.8e+02 184 206 .. 275 297 .. 267 301 .. 0.74 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00055 Beta-prop_Nup120_160 173 sastavavveseddtllftvclDhkLRvWslktgkcvatidlleerdpqes 223 ++++ +a+ + +d++++f+ D+ +R+W+++t + v +dl +++ FUN_000935-T1 142 TVNIRAALWS-KDSKFVFSGGEDKAMRLWDTRTMSEVKKVDLP-----NSV 186 4555555554.8******************************9.....222 PP == domain 2 score: -1.1 bits; conditional E-value: 1.5 Beta-prop_Nup120_160 184 eddtllftvclDhkLRvWslktg 206 +d++l + + D++LR+W+ + g FUN_000935-T1 275 PDGELYASGSEDGTLRLWQHTVG 297 66777777789*******87655 PP >> Ge1_WD40 WD40 region of Ge1, enhancer of mRNA-decapping protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 1.7 8.5e+02 189 215 .. 60 86 .. 53 94 .. 0.83 2 ? 0.7 0.0 0.57 2.9e+02 186 217 .. 98 129 .. 78 138 .. 0.77 3 ? -3.0 0.0 7.4 3.8e+03 188 202 .. 184 198 .. 155 210 .. 0.55 4 ? 5.8 0.0 0.016 8.3 190 215 .. 268 293 .. 259 299 .. 0.88 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1.7 Ge1_WD40 189 llveaalspdGtalatasadGlvkffq 215 + +a+l d t at +ad k + FUN_000935-T1 60 AVWSATLNKDATKAATGAADFSAKVWN 86 78899***************9999986 PP == domain 2 score: 0.7 bits; conditional E-value: 0.57 Ge1_WD40 186 edsllveaalspdGtalatasadGlvkffqiy 217 ++ ++ +sp+G l tas++ l++ f + FUN_000935-T1 98 HKHIVKIVDFSPNGHQLLTASNEKLMRIFDLQ 129 5555666789*************999999865 PP == domain 3 score: -3.0 bits; conditional E-value: 7.4 Ge1_WD40 188 sllveaalspdGtal 202 +++ ls dG +l FUN_000935-T1 184 NSVSSMVLSKDGSVL 198 234444555555554 PP == domain 4 score: 5.8 bits; conditional E-value: 0.016 Ge1_WD40 190 lveaalspdGtalatasadGlvkffq 215 + + +spdG a s dG+++++q FUN_000935-T1 268 VHCVRYSPDGELYASGSEDGTLRLWQ 293 567789*******************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 611 (0.0239186); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 87 (0.00340575); expected 25.5 (0.001) Passed Fwd filter: 50 (0.00195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 50 [number of targets reported over threshold] # CPU time: 0.48u 0.40s 00:00:00.88 Elapsed: 00:00:00.45 # Mc/sec: 2832.38 // Query: FUN_000936-T1 [L=379] Description: FUN_000936 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (379 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 672 (0.0263065); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3749.68 // Query: FUN_000937-T1 [L=705] Description: FUN_000937 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-58 196.9 0.0 8.9e-58 196.2 0.0 1.3 1 Pkinase Protein kinase domain 3.1e-27 96.0 0.0 5e-27 95.3 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.00033 20.4 0.0 0.0046 16.6 0.0 2.2 2 ABC1 ABC1 atypical kinase-like domain 0.00058 20.2 0.0 0.0012 19.1 0.0 1.5 1 APH Phosphotransferase enzyme family 0.001 18.9 0.0 0.0017 18.2 0.0 1.4 1 Kinase-like Kinase-like 0.0014 18.6 0.0 0.0031 17.5 0.0 1.5 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.0032 17.6 0.1 0.0085 16.2 0.1 1.8 1 RIO1 RIO domain 0.0057 16.8 2.1 0.015 15.5 0.1 2.4 2 DUF5523 Family of unknown function (DUF5523) ------ inclusion threshold ------ 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 TCAD9 Ternary complex associated domain 9 0.036 13.9 1.2 0.055 13.3 0.1 1.8 2 Choline_kinase Choline/ethanolamine kinase Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 196.2 0.0 3.5e-61 8.9e-58 1 262 [] 84 332 .. 84 332 .. 0.93 Alignments for each domain: == domain 1 score: 196.2 bits; conditional E-value: 3.5e-61 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkke...kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveg.gelfdllsrk 92 y+ +e++G+G+fg+V+++++k ++ vAiK ++k++ ++ e +++ +E +l+k++h+++v++++ f+ +d+++ v+E ++ ++l+d+l + FUN_000937-T1 84 YNLGEEIGQGGFGCVFSGTRKVDNLPVAIKLVEKSSVTEFFEidgQEIPSEAYFLNKMQHRHVVKFYQGFTLEDYYVYVMERPKNcQDLEDVLD-E 178 78899*********************************9999999************************************9876166*****6.7 PP Pkinase 93 galseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakelessskltsfvgtseYmAPEvlkskky.gkkvDvWslGvi 186 + l+e+e ++++kqil++ + ++gvvHrDlKp+NiL+d ++e+K++DFGla+el+ + +++f gt+ Ym+PE +k y g+++ vW+lG+i FUN_000937-T1 179 RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDeITDEVKLIDFGLASELQYEP-YNTFRGTKAYMPPEFVKFGWYdGSQSTVWALGMI 273 99**************************************66777**************99.*****************99999************ PP Pkinase 187 lyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 l++ll+ ++ f++ + ++l++ + + ++s+ea+dl++ +l+ +p +R++++++ +hpw+ FUN_000937-T1 274 LVNLLSSSMAFRKPE------EALSR-----------SPRLMANVSQEARDLISAMLNINPLTRPSLKQIRRHPWM 332 ************222......23333...........5677889*******************************7 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.3 0.0 2e-30 5e-27 3 256 .. 86 328 .. 84 329 .. 0.88 Alignments for each domain: == domain 1 score: 95.3 bits; conditional E-value: 2e-30 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtlkeeasee....ekeefleeaklmkklshpnivkllgvcteeepllivteyvegG.sLkefL 92 l+e++G+G fG V++gt k ++ +Va+K +++++ e + +e+ +ea +++k++h+++vk++ t e+ ++ v+e ++ +L+++L FUN_000937-T1 86 LGEEIGQGGFGCVFSGTRK----VDNLPVAIKLVEKSSVTEffeiDGQEIPSEAYFLNKMQHRHVVKFYQGFTLEDYYVYVMERPKNCqDLEDVL 176 789****************....999********776654422225899********************999988888888888777659***** PP PK_Tyr_Ser-Thr 93 rkkkeklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse.kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkft.sks 185 + + l+ +e ++ +qi ++ e++ +vHrdl N+L++e ++ vk+ DfGLa ++ +y+ ++ + +m+pE +k + + s+s FUN_000937-T1 177 DE--RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDEiTDEVKLIDFGLASEL----QYEPYNTFRGTKAYMPPEFVKFGWYDgSQS 265 99..7999************************************9788*************....6666677777889***********96589* PP PK_Tyr_Ser-Thr 186 DvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelve 256 vW+ G++l +++ +++ ++ e+l++ rl ++ +++e +l++ + +p Rp++k++++ FUN_000937-T1 266 TVWALGMILVNLLS------SSMAFRKPEEALSRSPRLMAN--VSQEARDLISAMLNINPLTRPSLKQIRR 328 **************......555666666788889998765..5999*********************976 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.1 2.6e+02 36 85 .. 88 139 .. 60 155 .. 0.76 2 ! 16.6 0.0 1.8e-06 0.0046 186 220 .. 202 237 .. 159 245 .. 0.73 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.1 ABC1 36 ePiAaASiaqVhkArlk.dgeeVavK.vqrpgvkkriesDlkllklllkvlk 85 e i+ ++ V+ ++ k d+ Va+K v + +v++ +e D + + + l+ FUN_000937-T1 88 EEIGQGGFGCVFSGTRKvDNLPVAIKlVEKSSVTEFFEIDGQEIPSEAYFLN 139 4577788999******99999*****66788999999999877766555555 PP == domain 2 score: 16.6 bits; conditional E-value: 1.8e-06 ABC1 186 edgffhaDphpGNllvrkdg.elvllDfGlmgelde 220 e+g++h D+ p+N+l+++ + e+ l+DfGl +el+ FUN_000937-T1 202 ENGVVHRDLKPANILLDEITdEVKLIDFGLASELQY 237 5799*************9888**********99975 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 4.9e-07 0.0012 137 197 .. 169 232 .. 151 233 .. 0.66 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 4.9e-07 APH 137 rllaaelkdrleeleeqllaallallpa...elppvlvHgDlhpgNllvd...dggrvsGviDFeda 197 +++ +++ d++ +e + +++++ l+a ++ ++vH+Dl+p N+l+d d+ + +iDF+ a FUN_000937-T1 169 CQDLEDVLDERLLTENESRRYFKQILDAticCEENGVVHRDLKPANILLDeitDEVK---LIDFGLA 232 44444444422223332333333333335557999****************966666...9****98 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 6.7e-07 0.0017 162 285 .. 201 316 .. 131 320 .. 0.86 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 6.7e-07 Kinase-like 162 qskglvhgkfsvdnllldekg.gvflggfeaLvragtkvvseve..kgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysiwclklPltlv 254 +++g+vh ++++ n+llde v+l +f+ ++ k++ PpE+ g y ++t +W+lG+ + + + + + ++ FUN_000937-T1 201 EENGVVHRDLKPANILLDEITdEVKLIDFGLASELQYEPYNTFRgtKAYMPPEFVKF--GWYDG---SQST----VWALGMILVNLLSSSMAFRKP 287 578***************96527******97766666666776677********987..65776...3444....8******************** PP Kinase-like 255 aeeakeewifklckkipekvklLlkkllrys 285 +e + + +l +++ ++ + L+ +l+ + FUN_000937-T1 288 EEALSRS--PRLMANVSQEARDLISAMLNIN 316 9999998..899****************987 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 1.2e-06 0.0031 95 166 .. 162 229 .. 144 236 .. 0.89 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1.2e-06 Kdo 95 lteklegaqdLedllaqwaelaeelrrallkavgrlirklhragvqHgdlyakhillqtekeeeakasliDl 166 ++e+ ++ qdLed+l + + l e+ r+ k++ + + gv H+dl + +ill++ ++ liD+ FUN_000937-T1 162 VMERPKNCQDLEDVLDE-RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDEIT---DEVKLIDF 229 8999************7.66999999********9999********************997...78999999 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.1 3.3e-06 0.0085 102 155 .. 179 236 .. 110 243 .. 0.82 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 3.3e-06 RIO1 102 e...eeeaeelyeevleemrklykeaglvHgDLseyNvlvde..dkvviIDvsQaveld 155 + e+e +++++++l+ + +e+g+vH DL N+l+de d+v +ID++ a el+ FUN_000937-T1 179 RlltENESRRYFKQILD-ATICCEENGVVHRDLKPANILLDEitDEVKLIDFGLASELQ 236 25656788888899998.788999****************974359*****98776665 PP >> DUF5523 Family of unknown function (DUF5523) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.1 5.7e-06 0.015 180 216 .. 155 191 .. 144 194 .. 0.94 2 ? -0.3 0.3 0.37 9.5e+02 23 75 .. 534 586 .. 512 641 .. 0.73 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 5.7e-06 DUF5523 180 lEdEGLYvgerPevsktnqnilEnRlLkqeegkkWFg 216 lEd +Yv erP+ ++ + +l+ RlL+++e++++F FUN_000937-T1 155 LEDYYVYVMERPKNCQDLEDVLDERLLTENESRRYFK 191 99999******************************96 PP == domain 2 score: -0.3 bits; conditional E-value: 0.37 DUF5523 23 keiqedersklssrvkfrdavkkvksksqvekglpsaeeaynfftfnfdpepe 75 ++ ++++r l+ r kfr k+v+++ ++e+ +p e + f+ ++e FUN_000937-T1 534 HRLKRNSRGDLNPRRKFRMCIKTVEHTVTSERAFPLRHEWRKQIGFDQSEEYG 586 4556777799999**********************999998888888777733 PP >> TCAD9 Ternary complex associated domain 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 7.5e-06 0.019 295 322 .. 201 230 .. 168 236 .. 0.86 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 7.5e-06 TCAD9 295 rvtasvHGDLNprNvLla..ednvyLIDya 322 ++vH DL p+N+Ll+ d+v LID+ FUN_000937-T1 201 EENGVVHRDLKPANILLDeiTDEVKLIDFG 230 55689**************99********5 PP >> Choline_kinase Choline/ethanolamine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 2.2e-05 0.055 164 192 .. 205 233 .. 124 241 .. 0.78 2 ? -2.6 0.1 1.4 3.7e+03 154 199 .. 384 439 .. 331 443 .. 0.69 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.2e-05 Choline_kinase 164 fcHnDlqesNileneetkelvlIDfEYss 192 H Dl+ Nil +e t+e++lIDf +s FUN_000937-T1 205 VVHRDLKPANILLDEITDEVKLIDFGLAS 233 46***********************8776 PP == domain 2 score: -2.6 bits; conditional E-value: 1.4 Choline_kinase 154 flesleepvvfcHnDlqesNile......neetkelv....lIDfEYssynyrgfD 199 ++ ++++ +cH +++ ++ ++++++++ lID+ s+ + D FUN_000937-T1 384 VTFLSQNEASLCHATSLSEQVMInsssneEHQDGQIQipseLIDYDDSTMDKESCD 439 44667778889998766666655466655444455542233677776666665555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (705 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 689 (0.026972); expected 510.9 (0.02) Passed bias filter: 463 (0.0181249); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.36u 0.43s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 6675.33 // Query: FUN_000938-T1 [L=452] Description: FUN_000938 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00058 19.5 0.6 0.00086 19.0 0.6 1.2 1 DUF6492 Family of unknown function (DUF6492) Domain annotation for each model (and alignments): >> DUF6492 Family of unknown function (DUF6492) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.6 3.4e-08 0.00086 27 213 .. 108 296 .. 103 317 .. 0.74 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 3.4e-08 DUF6492 27 Lfkslrkfakpellhkflivvpdeeveevkelakawsd.fdievideselvpefskrkqvrgWhrqqi.iKlaaaarieteffl.vlDaDviclrp 119 Lf+s++ f ++ k+++v ++e + + + ++++ + + i + e + + W + ++ + + a++ ++ ++ ++D D +++ FUN_000938-T1 108 LFRSISLFWPKN--TKVVVVLDKE-NAADRVYGSKIKKsAPSKKITFEVCYMEAYPPEMIHHWGKMRMyMDMMHADLCTNATYVgLVDVDTLFTTA 200 788888887763..2344444444.34444444444443444444445555667777789999887763778889999998888678********* PP DUF6492 120 fdledlipdgkallvi.earsahpkwweaaaklLkvdpnsdriglgvtPavlskqlvkelkerlealkgrdWrrvLlsnk...kvdwtEYtLYyla 211 ++ ++ gk ++ +++ p w ++ + +L++++ + + + P++++++ ke ++++ +l+g+d+++v+ +v +t Y Y ++ FUN_000938-T1 201 VTPSLVLEAGKPVVTGrIGQPRIPCWMKSGEYVLGIKQVM--QCMHYFPVTFKTAHLKEFRDYVAKLYGKDFKDVIAEAArksNVRYTCYCHYSMM 294 ***********9876515788999999**********998..88999****************************987763335666666666555 PP DUF6492 212 ae 213 + FUN_000938-T1 295 CN 296 43 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (452 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 654 (0.0256019); expected 510.9 (0.02) Passed bias filter: 452 (0.0176943); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4331.15 // Query: FUN_000939-T1 [L=698] Description: FUN_000939 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-58 196.1 0.0 1.6e-57 195.4 0.0 1.4 1 Pkinase Protein kinase domain 3.8e-28 99.0 0.0 6.1e-28 98.3 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinas 0.00011 21.9 0.0 0.0018 18.0 0.0 2.2 2 ABC1 ABC1 atypical kinase-like domain 0.00012 21.9 0.0 0.00023 21.0 0.0 1.5 1 Kinase-like Kinase-like 0.00043 20.6 0.0 0.00098 19.4 0.0 1.6 2 APH Phosphotransferase enzyme family 0.0013 18.7 0.1 0.0027 17.7 0.1 1.4 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.0045 17.1 0.1 0.012 15.8 0.1 1.8 1 RIO1 RIO domain ------ inclusion threshold ------ 0.013 15.7 0.1 0.013 15.7 0.1 2.8 3 DUF5523 Family of unknown function (DUF5523) 0.017 15.0 0.1 0.035 13.9 0.1 1.5 1 Choline_kinase Choline/ethanolamine kinase 0.03 14.0 0.0 0.064 12.9 0.0 1.6 1 TCAD9 Ternary complex associated domain 9 0.097 13.3 0.0 0.37 11.4 0.0 1.9 2 YLDV-IL18BP-like Yaba-Like Disease Virus IL18BP Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 195.4 0.0 6.9e-61 1.6e-57 1 262 [] 84 332 .. 84 332 .. 0.93 Alignments for each domain: == domain 1 score: 195.4 bits; conditional E-value: 6.9e-61 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkke...kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveg.gelfdllsrk 92 y+ +e++G+G+fg+V+++++k ++ vAiK ++k++ ++ e +++ +E +l+k++h+++v++++ f+ +d+++ v+E ++ ++l+d+l + FUN_000939-T1 84 YNLGEEIGQGGFGCVFSGTRKVDNLPVAIKLVEKSSVTEFFEidgQEIPSEAYFLNKMQHRHVVKFYQGFTLEDYYVYVMERPQNcQDLEDVLD-E 178 78899*********************************9999999************************************9765166*****6.7 PP Pkinase 93 galseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakelessskltsfvgtseYmAPEvlkskky.gkkvDvWslGvi 186 + l+e+e ++++kqil++ + ++gvvHrDlKp+NiL+d ++e+K++DFGla++l+ + +++f gt+ Ym+PE +k y g+++ vW+lG+i FUN_000939-T1 179 RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDeITDEIKLIDFGLASKLQYEP-YDTFRGTKAYMPPEFVKFGWYdGSQSTVWALGMI 273 99**************************************66777**************99.*****************99999************ PP Pkinase 187 lyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 l++l++ ++ f++ + ++l++ + + ++s+e++dl++ +l+ +p +R++++++ +hpw+ FUN_000939-T1 274 LVNLMSSSMAFRKPE------EALSR-----------SPRLTANVSQEVRDLISAMLNINPLTRPSLKQIRRHPWM 332 ************222......23333...........5677899*******************************7 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.3 0.0 2.6e-31 6.1e-28 3 256 .. 86 328 .. 84 329 .. 0.88 Alignments for each domain: == domain 1 score: 98.3 bits; conditional E-value: 2.6e-31 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtlkeeasee....ekeefleeaklmkklshpnivkllgvcteeepllivteyvegG.sLkefL 92 l+e++G+G fG V++gt k ++ +Va+K +++++ e + +e+ +ea +++k++h+++vk++ t e+ ++ v+e ++ +L+++L FUN_000939-T1 86 LGEEIGQGGFGCVFSGTRK----VDNLPVAIKLVEKSSVTEffeiDGQEIPSEAYFLNKMQHRHVVKFYQGFTLEDYYVYVMERPQNCqDLEDVL 176 789****************....999********776654422225899********************999988888888888776659***** PP PK_Tyr_Ser-Thr 93 rkkkeklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse.kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkft.sks 185 + + l+ +e ++ +qi ++ e++ +vHrdl N+L++e ++ +k+ DfGLa ++ +y+ ++ + +m+pE +k + + s+s FUN_000939-T1 177 DE--RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDEiTDEIKLIDFGLASKL----QYEPYDTFRGTKAYMPPEFVKFGWYDgSQS 265 99..7999************************************9788*************....6777777778889***********96589* PP PK_Tyr_Ser-Thr 186 DvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelve 256 vW+ G++l +++ +++ ++ e+l++ rl+++ +++e+ +l++ + +p Rp++k++++ FUN_000939-T1 266 TVWALGMILVNLMS------SSMAFRKPEEALSRSPRLTAN--VSQEVRDLISAMLNINPLTRPSLKQIRR 328 **************......556666666788999999875..5************************986 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.095 2.2e+02 36 85 .. 88 139 .. 59 156 .. 0.75 2 ! 18.0 0.0 7.8e-07 0.0018 186 220 .. 202 237 .. 160 246 .. 0.73 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.095 ABC1 36 ePiAaASiaqVhkArlk.dgeeVavK.vqrpgvkkriesDlkllklllkvlk 85 e i+ ++ V+ ++ k d+ Va+K v + +v++ +e D + + + l+ FUN_000939-T1 88 EEIGQGGFGCVFSGTRKvDNLPVAIKlVEKSSVTEFFEIDGQEIPSEAYFLN 139 5678888999******99999*****66788999999999877766665555 PP == domain 2 score: 18.0 bits; conditional E-value: 7.8e-07 ABC1 186 edgffhaDphpGNllvrkdg.elvllDfGlmgelde 220 e+g++h D+ p+N+l+++ + e+ l+DfGl ++l+ FUN_000939-T1 202 ENGVVHRDLKPANILLDEITdEIKLIDFGLASKLQY 237 5799*************9888*********999875 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 1e-07 0.00023 162 285 .. 201 316 .. 131 320 .. 0.85 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1e-07 Kinase-like 162 qskglvhgkfsvdnllldekg.gvflggfeaLvragtkvvseve..kgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysiwclklPltlv 254 +++g+vh ++++ n+llde ++l +f+ + + k++ PpE+ g y ++t +W+lG+ + + + + + ++ FUN_000939-T1 201 EENGVVHRDLKPANILLDEITdEIKLIDFGLASKLQYEPYDTFRgtKAYMPPEFVKF--GWYDG---SQST----VWALGMILVNLMSSSMAFRKP 287 578***************96527******98777776666555456********987..65776...3444....8******************** PP Kinase-like 255 aeeakeewifklckkipekvklLlkkllrys 285 +e + + +l +++ ++v+ L+ +l+ + FUN_000939-T1 288 EEALSRS--PRLTANVSQEVRDLISAMLNIN 316 *999998..89999***************87 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 5.7 1.3e+04 74 106 .. 51 83 .. 36 94 .. 0.73 2 ! 19.4 0.0 4.2e-07 0.00098 138 198 .. 170 233 .. 133 234 .. 0.70 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 5.7 APH 74 lmeylpGedlernalseaeagalledlgeaLar 106 + e l+ +++++++++e+ ++++ ++l + La+ FUN_000939-T1 51 FTENLEKRTPDEDHQEEDYQDEFTKKLCRKLAE 83 566677777777777788888888888777776 PP == domain 2 score: 19.4 bits; conditional E-value: 4.2e-07 APH 138 llaaelkdrleeleeqllaallallpa...elppvlvHgDlhpgNllvd...dggrvsGviDFedag 198 ++ +++ d++ +e + +++++ l+a ++ ++vH+Dl+p N+l+d d+ + +iDF+ a+ FUN_000939-T1 170 QDLEDVLDERLLTENESRRYFKQILDAticCEENGVVHRDLKPANILLDeitDEIK---LIDFGLAS 233 4444444422222222333333333335556999****************966666...8****985 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.1 1.2e-06 0.0027 95 166 .. 162 229 .. 144 236 .. 0.89 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 1.2e-06 Kdo 95 lteklegaqdLedllaqwaelaeelrrallkavgrlirklhragvqHgdlyakhillqtekeeeakasliDl 166 ++e+ ++ qdLed+l + + l e+ r+ k++ + + gv H+dl + +ill++ ++ liD+ FUN_000939-T1 162 VMERPQNCQDLEDVLDE-RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDEIT---DEIKLIDF 229 899*************7.66999999********9999********************997...78999999 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.1 5e-06 0.012 102 153 .. 179 234 .. 110 243 .. 0.81 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 5e-06 RIO1 102 e...eeeaeelyeevleemrklykeaglvHgDLseyNvlvde..dkvviIDvsQave 153 + e+e +++++++l+ + +e+g+vH DL N+l+de d++ +ID++ a + FUN_000939-T1 179 RlltENESRRYFKQILD-ATICCEENGVVHRDLKPANILLDEitDEIKLIDFGLASK 234 25656788888899998.788999****************974359*****986655 PP >> DUF5523 Family of unknown function (DUF5523) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 1.2 5 1.2e+04 109 121 .. 56 68 .. 22 82 .. 0.48 2 ? 15.7 0.1 5.5e-06 0.013 180 216 .. 155 191 .. 144 194 .. 0.94 3 ? 2.1 1.8 0.079 1.8e+02 6 93 .. 517 605 .. 512 651 .. 0.68 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 5 DUF5523 109 eeekdeeellvkk 121 e+++ +e++ +++ FUN_000939-T1 56 EKRTPDEDHQEED 68 1222222222222 PP == domain 2 score: 15.7 bits; conditional E-value: 5.5e-06 DUF5523 180 lEdEGLYvgerPevsktnqnilEnRlLkqeegkkWFg 216 lEd +Yv erP+ ++ + +l+ RlL+++e++++F FUN_000939-T1 155 LEDYYVYVMERPQNCQDLEDVLDERLLTENESRRYFK 191 99999******************************96 PP == domain 3 score: 2.1 bits; conditional E-value: 0.079 DUF5523 6 eresetrldkeadkeeekeiqedersklssrvkfrdavkkvksksqvekglpsaeeaynfftfnfdpepeeseekkk.kkekeekeqee 93 r +++ d+e ++ ++ ++++r l+ r kfr k+v+++ ++++ +p+ e + f+ ++e +++ ++ + ++ +q+e FUN_000939-T1 517 RRMAQNYSDRERNELFAHRLKRNSRGDLNPRKKFRMCIKTVEHTVTSKRAFPVRHEWRKQIGFDQSEEYGPRRNSETyELLEKGLRQSE 605 445555556666666667778888899*****************************999999998888444222222022222333333 PP >> Choline_kinase Choline/ethanolamine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.1 1.5e-05 0.035 164 192 .. 205 233 .. 130 241 .. 0.78 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.5e-05 Choline_kinase 164 fcHnDlqesNileneetkelvlIDfEYss 192 H Dl+ Nil +e t+e++lIDf +s FUN_000939-T1 205 VVHRDLKPANILLDEITDEIKLIDFGLAS 233 46***********************8887 PP >> TCAD9 Ternary complex associated domain 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 2.8e-05 0.064 295 322 .. 201 230 .. 159 237 .. 0.87 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 2.8e-05 TCAD9 295 rvtasvHGDLNprNvLla..ednvyLIDya 322 ++vH DL p+N+Ll+ d+ LID+ FUN_000939-T1 201 EENGVVHRDLKPANILLDeiTDEIKLIDFG 230 55689*************999*******95 PP >> YLDV-IL18BP-like Yaba-Like Disease Virus IL18BP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00016 0.37 36 91 .. 47 102 .. 42 111 .. 0.92 2 ? -3.3 0.0 6 1.4e+04 68 82 .. 213 227 .. 203 230 .. 0.78 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00016 YLDV-IL18BP-like 36 nnnsfveqlngklykeklrisrkkkegvkllradLvlkniteelkntklsCvLvDl 91 ++f+e+l++ +e + + + e +k+l ++L +n+ ee+ + + Cv + FUN_000939-T1 47 VKETFTENLEKRTPDEDHQEEDYQDEFTKKLCRKLAEYNLGEEIGQGGFGCVFSGT 102 5789***************9********************************9765 PP == domain 2 score: -3.3 bits; conditional E-value: 6 YLDV-IL18BP-like 68 adLvlkniteelknt 82 a+++l++it+e+k FUN_000939-T1 213 ANILLDEITDEIKLI 227 6788999**999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (698 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 799 (0.0312781); expected 510.9 (0.02) Passed bias filter: 509 (0.0199256); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.36u 0.43s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 6575.80 // Query: FUN_000940-T1 [L=425] Description: FUN_000940 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.001 18.7 0.3 0.0015 18.2 0.3 1.2 1 DUF6492 Family of unknown function (DUF6492) Domain annotation for each model (and alignments): >> DUF6492 Family of unknown function (DUF6492) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.3 5.9e-08 0.0015 27 213 .. 81 269 .. 77 291 .. 0.72 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 5.9e-08 DUF6492 27 Lfkslrkfakpellhkflivvpdeeveevkelakawsd.fdievideselvpefskrkqvrgWhrqqi.iKlaaaarieteffl.vlDaDviclrp 119 Lf+s++ f ++ k ++vv d+e + + + ++++ + + i + e + + W + ++ + + a++ ++ ++ ++D D +++ FUN_000940-T1 81 LFRSISLFWPKN--TK-VVVVLDKENAGDRVYGSKIKKsAPSKKITFEVCYMEAYPPEMIHHWGKMRMyMDMMHADLCTNATYVgLVDVDTLFTTA 173 677777766652..22.3333333333334444444333444444444445556666778888877653678888888888888578********* PP DUF6492 120 fdledlipdgkallvi.earsahpkwweaaaklLkvdpnsdriglgvtPavlskqlvkelkerlealkgrdWrrvLlsnk...kvdwtEYtLYyla 211 ++ ++ gk ++ +++ p w ++ + +L++++ + + + P++++++ ke ++++ +l+g+d+++v++ +v +t Y Y ++ FUN_000940-T1 174 VTPSLVLEAGKPVVTGrIGQPRIPCWMKSGEYVLGIKQVM--QCMHYFPVTFKTAHLKEFRDYVAKLHGKDFKDVITEAAsksNVRYTCYCHYSMM 267 ***********9876515788999999**********998..88999****************************987653336777777777665 PP DUF6492 212 ae 213 + FUN_000940-T1 268 CN 269 43 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (425 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 896 (0.0350754); expected 510.9 (0.02) Passed bias filter: 609 (0.0238403); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 4260.13 // Query: FUN_000941-T1 [L=677] Description: FUN_000941 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-57 194.8 0.0 4.1e-57 194.0 0.0 1.4 1 Pkinase Protein kinase domain 5.2e-27 95.3 0.0 8.6e-27 94.5 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.00017 21.3 0.0 0.0017 18.0 0.0 2.1 2 ABC1 ABC1 atypical kinase-like domain 0.00055 20.3 0.0 0.00098 19.4 0.0 1.4 1 APH Phosphotransferase enzyme family 0.00061 19.6 0.1 0.0014 18.5 0.0 1.6 2 Kinase-like Kinase-like 0.0013 18.7 0.1 0.0026 17.7 0.1 1.4 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.0065 16.6 0.9 0.013 15.6 0.0 2.0 2 RIO1 RIO domain ------ inclusion threshold ------ 0.012 15.8 0.1 0.012 15.8 0.1 3.2 3 DUF5523 Family of unknown function (DUF5523) 0.02 14.7 0.1 0.04 13.7 0.1 1.4 1 Choline_kinase Choline/ethanolamine kinase 0.036 13.7 0.0 0.065 12.9 0.0 1.4 1 TCAD9 Ternary complex associated domain 9 2.5 7.5 6.3 0.61 9.5 0.2 2.6 3 MPS2 Monopolar spindle protein 2 Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 194.0 0.0 1.8e-60 4.1e-57 1 262 [] 63 311 .. 63 311 .. 0.93 Alignments for each domain: == domain 1 score: 194.0 bits; conditional E-value: 1.8e-60 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkke...kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveg.gelfdllsrk 92 y+ +e++G+G+fg+V+++++k ++ vAiK ++k+ ++ e +++ +E +l+k++h+++v++++ f+ +d+++ v+E ++ ++l+d+l + FUN_000941-T1 63 YNLGEEIGQGGFGCVFSGTRKIDNLPVAIKLVEKSYVTEFFEidgQEIPSEAYFLNKVHHRHVVKFYQGFTLEDYYVYVMERPQNcQDLEDVLD-E 157 78899*******************************999998999************************************9765166*****6.7 PP Pkinase 93 galseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakelessskltsfvgtseYmAPEvlkskky.gkkvDvWslGvi 186 + l+e+e ++++kqil++ + ++gvvHrDlKp+NiL+d ++e+K++DFGla++l+ + +++f gt+ Ym+PE +k y g+++ vW+lG+i FUN_000941-T1 158 RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDeITDEIKLIDFGLASKLQYEP-YNTFRGTKAYMPPEFVKFGWYdGSQSTVWALGMI 252 99**************************************66777**************99.*****************99999************ PP Pkinase 187 lyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 l++ll+ ++ f++ + ++l++ + + ++s+ea+dl++ +l+ +p +R+t++++ +hpw+ FUN_000941-T1 253 LVNLLSSSMAFRKPE------EALSR-----------SPRLMANVSQEARDLISAMLNINPLTRPTLKQIRRHPWM 311 ************222......23333...........5677889*******************************7 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 94.5 0.0 3.7e-30 8.6e-27 3 256 .. 65 307 .. 63 308 .. 0.88 Alignments for each domain: == domain 1 score: 94.5 bits; conditional E-value: 3.7e-30 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtlkeeasee....ekeefleeaklmkklshpnivkllgvcteeepllivteyvegG.sLkefL 92 l+e++G+G fG V++gt k ++ +Va+K +++++ e + +e+ +ea +++k++h+++vk++ t e+ ++ v+e ++ +L+++L FUN_000941-T1 65 LGEEIGQGGFGCVFSGTRK----IDNLPVAIKLVEKSYVTEffeiDGQEIPSEAYFLNKVHHRHVVKFYQGFTLEDYYVYVMERPQNCqDLEDVL 155 789****************....899********887665422225899********************999988888888888776659***** PP PK_Tyr_Ser-Thr 93 rkkkeklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse.kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkft.sks 185 + + l+ +e ++ +qi ++ e++ +vHrdl N+L++e ++ +k+ DfGLa ++ +y+ ++ + +m+pE +k + + s+s FUN_000941-T1 156 DE--RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDEiTDEIKLIDFGLASKL----QYEPYNTFRGTKAYMPPEFVKFGWYDgSQS 244 99..7999************************************9788*************....6666677777889***********96589* PP PK_Tyr_Ser-Thr 186 DvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelve 256 vW+ G++l +++ +++ ++ e+l++ rl ++ +++e +l++ + +p Rpt+k++++ FUN_000941-T1 245 TVWALGMILVNLLS------SSMAFRKPEEALSRSPRLMAN--VSQEARDLISAMLNINPLTRPTLKQIRR 307 **************......556666666788889998765..599**********************976 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.15 3.4e+02 36 85 .. 67 118 .. 38 134 .. 0.74 2 ! 18.0 0.0 7.3e-07 0.0017 174 220 .. 162 216 .. 125 223 .. 0.74 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.15 ABC1 36 ePiAaASiaqVhkArlk.dgeeVavK.vqrpgvkkriesDlkllklllkvlk 85 e i+ ++ V+ ++ k d+ Va+K v + v++ +e D + + + l+ FUN_000941-T1 67 EEIGQGGFGCVFSGTRKiDNLPVAIKlVEKSYVTEFFEIDGQEIPSEAYFLN 118 5577888999******99999*****55677899999999777666555555 PP == domain 2 score: 18.0 bits; conditional E-value: 7.3e-07 ABC1 174 eklvelfleqif.......edgffhaDphpGNllvrkdg.elvllDfGlmgelde 220 e+ + +++qi+ e+g++h D+ p+N+l+++ + e+ l+DfGl ++l+ FUN_000941-T1 162 ENESRRYFKQILdaticceENGVVHRDLKPANILLDEITdEIKLIDFGLASKLQY 216 44455555555422222325799*************9888*********999875 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 4.2e-07 0.00098 138 198 .. 149 212 .. 119 213 .. 0.69 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 4.2e-07 APH 138 llaaelkdrleeleeqllaallallpa...elppvlvHgDlhpgNllvd...dggrvsGviDFedag 198 ++ +++ d++ +e + +++++ l+a ++ ++vH+Dl+p N+l+d d+ + +iDF+ a+ FUN_000941-T1 149 QDLEDVLDERLLTENESRRYFKQILDAticCEENGVVHRDLKPANILLDeitDEIK---LIDFGLAS 212 4444444422222222333333333335556999****************966666...8****985 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 5.8e-07 0.0014 162 285 .. 180 295 .. 121 299 .. 0.87 2 ? -3.0 0.0 2.1 4.8e+03 47 97 .. 494 544 .. 482 551 .. 0.68 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 5.8e-07 Kinase-like 162 qskglvhgkfsvdnllldekg.gvflggfeaLvragtkvvseve..kgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysiwclklPltlv 254 +++g+vh ++++ n+llde ++l +f+ + ++ k++ PpE+ g y ++t +W+lG+ + + + + + ++ FUN_000941-T1 180 EENGVVHRDLKPANILLDEITdEIKLIDFGLASKLQYEPYNTFRgtKAYMPPEFVKF--GWYDG---SQST----VWALGMILVNLLSSSMAFRKP 266 578***************96527******98888877777877677********987..65776...3444....8******************** PP Kinase-like 255 aeeakeewifklckkipekvklLlkkllrys 285 +e + + +l +++ ++ + L+ +l+ + FUN_000941-T1 267 EEALSRS--PRLMANVSQEARDLISAMLNIN 295 9999998..899****************987 PP == domain 2 score: -3.0 bits; conditional E-value: 2.1 Kinase-like 47 mkekpskkdleklkeavlaiallrgiknpkeAkaylrlllpfdlv..kipkkk 97 + + +++d ++ ++ lai+l r ++ + + ++++ +++ v ++++k+ FUN_000941-T1 494 SRRRMAQNDSDREPNELLAIRLKR--NSRGDLNPRRKFRMCIKTVehTVTSKR 544 556778888888888899998833..567777778888888877722355555 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.1 1.1e-06 0.0026 95 166 .. 141 208 .. 123 215 .. 0.89 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 1.1e-06 Kdo 95 lteklegaqdLedllaqwaelaeelrrallkavgrlirklhragvqHgdlyakhillqtekeeeakasliDl 166 ++e+ ++ qdLed+l + + l e+ r+ k++ + + gv H+dl + +ill++ ++ liD+ FUN_000941-T1 141 VMERPQNCQDLEDVLDE-RLLTENESRRYFKQILDATICCEENGVVHRDLKPANILLDEIT---DEIKLIDF 208 899*************7.66999999********9999********************997...78999999 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.2 2.7 6.3e+03 13 43 .. 22 53 .. 14 66 .. 0.59 2 ! 15.6 0.0 5.6e-06 0.013 102 154 .. 158 214 .. 137 222 .. 0.76 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 2.7 RIO1 13 vavKiyktgtteFkkvkkyrsg.dkrfkarks 43 +K+ t t++F+++ + +++++++ + FUN_000941-T1 22 SDLKVKETFTENFEERTPDEDHqEEDYQDEFT 53 45788888889998866554440334444433 PP == domain 2 score: 15.6 bits; conditional E-value: 5.6e-06 RIO1 102 e...eeeaeelyeevleemrklykeaglvHgDLseyNvlvde..dkvviIDvsQavel 154 + e+e +++++++l+ + +e+g+vH DL N+l+de d++ +ID++ a +l FUN_000941-T1 158 RlltENESRRYFKQILD-ATICCEENGVVHRDLKPANILLDEitDEIKLIDFGLASKL 214 25556788888999998.788999****************974359*****9876655 PP >> DUF5523 Family of unknown function (DUF5523) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 3.5 3.4 7.9e+03 81 123 .. 24 49 .. 6 63 .. 0.37 2 ? 15.8 0.1 5e-06 0.012 180 216 .. 134 170 .. 121 173 .. 0.94 3 ? 3.3 0.6 0.033 76 5 96 .. 495 587 .. 492 628 .. 0.72 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 3.4 DUF5523 81 kkkkekeekeqeeeeeeeeeeeeeeeqeeeekdeeellvkkee 123 k ke+ ++ + ee++ +e++ +++ + FUN_000941-T1 24 LKVKETFTE-----------------NFEERTPDEDHQEEDYQ 49 111111111.................12222222222222222 PP == domain 2 score: 15.8 bits; conditional E-value: 5e-06 DUF5523 180 lEdEGLYvgerPevsktnqnilEnRlLkqeegkkWFg 216 lEd +Yv erP+ ++ + +l+ RlL+++e++++F FUN_000941-T1 134 LEDYYVYVMERPQNCQDLEDVLDERLLTENESRRYFK 170 99999******************************96 PP == domain 3 score: 3.3 bits; conditional E-value: 0.033 DUF5523 5 reresetrldkeadkeeekeiqedersklssrvkfrdavkkvksksqvekglpsaeeaynfftfnfdpepeeseekkkkk.ekeekeqeeeee 96 r r ++++ d+e+++ + ++++r l+ r kfr k+v+++ ++++ +p+ e + f+ ++e +++ ++ + ++ +q+e ++ FUN_000941-T1 495 RRRMAQNDSDREPNELLAIRLKRNSRGDLNPRRKFRMCIKTVEHTVTSKRAFPVRHEWRKQIGFDQSEEYGSRRNSETYElLEKGLRQSEGHR 587 556667777778777777788899999******************************999999999998655333333220333333333222 PP >> Choline_kinase Choline/ethanolamine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 1.7e-05 0.04 164 192 .. 184 212 .. 117 219 .. 0.78 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.7e-05 Choline_kinase 164 fcHnDlqesNileneetkelvlIDfEYss 192 H Dl+ Nil +e t+e++lIDf +s FUN_000941-T1 184 VVHRDLKPANILLDEITDEIKLIDFGLAS 212 46***********************8877 PP >> TCAD9 Ternary complex associated domain 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 2.8e-05 0.065 295 321 .. 180 208 .. 140 215 .. 0.87 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 2.8e-05 TCAD9 295 rvtasvHGDLNprNvLla..ednvyLIDy 321 ++vH DL p+N+Ll+ d+ LID+ FUN_000941-T1 180 EENGVVHRDLKPANILLDeiTDEIKLIDF 208 55689*************999*******9 PP >> MPS2 Monopolar spindle protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.2 0.00026 0.61 99 184 .. 342 430 .. 335 443 .. 0.77 2 ? -1.8 0.5 0.71 1.7e+03 220 247 .. 570 597 .. 498 642 .. 0.75 3 ? -0.3 0.3 0.26 6.1e+02 209 244 .. 621 656 .. 611 665 .. 0.80 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00026 MPS2 99 kkiaedgvldrlqdsqavdGiqdekisalelkeevkrlreqvrvlsskrdkkdreisaidvilldl...lkkdeePetsrrilrkyksl 184 +ia+dg ld l a d ++ + + + l eq + ss ++++ i +l+d +e+ + + +++++ l FUN_000941-T1 342 VSIAKDGCLDVLSSVAAQDCHVASLNQNEASQCHATSLSEQAMINSSSNEEHQDGQIQIPSELIDYddsTMDKESCNLESKYNKRFRPL 430 489*****************************************999998865555555555554400044455666677777777766 PP == domain 2 score: -1.8 bits; conditional E-value: 0.71 MPS2 220 kekydlleeeyefykqrriqksndsike 247 e y+lle+ + +++r++++ + ++e FUN_000941-T1 570 SETYELLEKGLRQSEGHRKKRGRNKLNE 597 4778999998888888888888876554 PP == domain 3 score: -0.3 bits; conditional E-value: 0.26 MPS2 209 llelrkrvsklkekydlleeeyefykqrriqksnds 244 ++lr+r+ ++ke +l+ ++y + +i++ +++ FUN_000941-T1 621 ETHLRRRIKNVKEGGRFLHTRLRWYLNEKIENNDKA 656 478999************999999999998876655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (677 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1234 (0.0483069); expected 510.9 (0.02) Passed bias filter: 724 (0.0283421); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.38u 0.42s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 6426.88 // Query: FUN_000942-T1 [L=298] Description: FUN_000942 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-36 122.1 11.1 4e-11 42.8 0.1 5.5 5 NHL NHL repeat 7.3e-12 45.9 0.2 0.0007 19.8 0.0 4.6 4 SGL SMP-30/Gluconolactonase/LRE-like region 2.4e-10 40.6 0.2 0.00028 20.6 0.0 3.1 3 DUF5128 6-bladed beta-propeller 1.3e-06 28.1 0.0 0.25 10.7 0.0 4.0 5 TEN_NHL Teneurin NHL domain 0.00011 22.0 0.4 0.035 13.7 0.1 3.3 4 PhoX Alkaline phosphatase PhoX 0.00046 20.0 0.0 3.1 7.4 0.0 3.1 3 DUF5711 Family of unknown function (DUF5711) 0.00068 19.0 0.0 0.0066 15.8 0.0 2.1 1 Vgb_lyase Virginiamycin B lyase family ------ inclusion threshold ------ 0.017 14.3 0.0 1.5 7.9 0.0 3.0 4 TrAA12 TrAA12-like 0.046 14.0 0.1 0.094 13.0 0.1 1.5 1 DUF6129 Family of unknown function (DUF6129) 0.083 13.2 0.2 7.9 6.9 0.0 3.2 3 SSL_N Strictosidine synthase-like, N-terminal 0.11 12.7 0.1 2.5 8.3 0.0 3.4 5 Proteasome_A_N Proteasome subunit A N-terminal signature 0.19 12.0 0.2 1.4 9.2 0.1 2.3 3 FokI_cleav_dom FokI, cleavage domain Domain annotation for each model (and alignments): >> NHL NHL repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.8 0.1 1.9e-14 4e-11 1 28 [] 17 44 .. 17 44 .. 0.99 2 ! 16.5 0.1 4.3e-06 0.0091 1 25 [. 64 88 .. 64 89 .. 0.95 3 ! 13.4 0.0 4e-05 0.084 1 18 [. 106 123 .. 106 134 .. 0.88 4 ! 34.8 0.6 6.7e-12 1.4e-08 1 28 [] 196 223 .. 196 223 .. 0.99 5 ! 18.1 0.0 1.3e-06 0.0027 1 27 [. 243 269 .. 243 270 .. 0.96 Alignments for each domain: == domain 1 score: 42.8 bits; conditional E-value: 1.9e-14 NHL 1 fnrPhGvavdsdGdiyVaDsenhrvqvF 28 f++PhG+av+s+G++ V D++nhr+q+F FUN_000942-T1 17 FQYPHGIAVSSSGEVAVVDTCNHRIQIF 44 99*************************9 PP == domain 2 score: 16.5 bits; conditional E-value: 4.3e-06 NHL 1 fnrPhGvavdsdGdiyVaDsenhrv 25 +n+P G + d G+++ aDs+nhr+ FUN_000942-T1 64 LNFPDGATFDHEGNLVLADSDNHRL 88 799*********************8 PP == domain 3 score: 13.4 bits; conditional E-value: 4e-05 NHL 1 fnrPhGvavdsdGdiyVa 18 +++P+Gv+ +s G+i V+ FUN_000942-T1 106 LRNPWGVCTTSEGNIAVC 123 789**************8 PP == domain 4 score: 34.8 bits; conditional E-value: 6.7e-12 NHL 1 fnrPhGvavdsdGdiyVaDsenhrvqvF 28 fnrP+Gvavd+ ++++V+D +n+r+qvF FUN_000942-T1 196 FNRPRGVAVDQHDQLLVCDGWNNRIQVF 223 9**************************9 PP == domain 5 score: 18.1 bits; conditional E-value: 1.3e-06 NHL 1 fnrPhGvavdsdGdiyVaDsenhrvqv 27 + +P ++a++ dG+i+V+ + hrvqv FUN_000942-T1 243 LTFPVDLAIGRDGRIFVSELKGHRVQV 269 679***********************8 PP >> SGL SMP-30/Gluconolactonase/LRE-like region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 3.3e-07 0.0007 131 219 .. 15 100 .. 4 104 .. 0.83 2 ! 10.7 0.0 0.0002 0.42 184 231 .. 107 157 .. 99 168 .. 0.76 3 ? 1.3 0.0 0.14 3e+02 193 218 .. 159 184 .. 154 188 .. 0.85 4 ! 9.4 0.0 0.00047 1 183 219 .. 195 232 .. 162 246 .. 0.81 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 3.3e-07 SGL 131 dgltisNGlawspDgktlYlaDslarkiyafdydaeggelsnrrvfadfkkgegepDGlavDaeGgvwvAlwgggkvvrfdpdGkllee 219 +++ + G+a s+ g++ ++D+ +++i+ f+ d e + + + +++ + + pDG++ D eG++ A +++++ +++dGk+++ FUN_000942-T1 15 GEFQYPHGIAVSSSGEVA-VVDTCNHRIQIFNEDGEFHRAFGSQ-GINIGDLN-FPDGATFDHEGNLVLADSDNHRLSFHSQDGKVIRI 100 567889999999999877.59***********987666444444.35777776.7*******************************986 PP == domain 2 score: 10.7 bits; conditional E-value: 0.0002 SGL 184 gepDGlavDaeGgvwvAlw.gggkvvrfdpdGklleeielP.ak.rptsca 231 +p G+++++eG++ v+ ++ ++++f+p+G+ll + P + rp+ +a FUN_000942-T1 107 RNPWGVCTTSEGNIAVCSGgDKRQIQVFSPEGSLLMSFGDPsSRhRPSYVA 157 5688*************9834559**********99888774335666665 PP == domain 3 score: 1.3 bits; conditional E-value: 0.14 SGL 193 aeGgvwvAlwgggkvvrfdpdGklle 218 ++++++v ++g++v fd +G+ l FUN_000942-T1 159 SHDMYFVSYTDGQCVKAFDSQGRSLF 184 57899999**************9765 PP == domain 4 score: 9.4 bits; conditional E-value: 0.00047 SGL 183 e.gepDGlavDaeGgvwvAlwgggkvvrfdpdGkllee 219 + +p G+avD+++++ v+ ++++++f+ +Gk l++ FUN_000942-T1 195 QfNRPRGVAVDQHDQLLVCDGWNNRIQVFTLEGKFLHK 232 245799**************99************9986 PP >> DUF5128 6-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 3.5e-05 0.074 42 82 .. 17 58 .. 12 119 .. 0.83 2 ! 5.5 0.0 0.0052 11 46 100 .. 154 208 .. 151 210 .. 0.84 3 ! 20.6 0.0 1.3e-07 0.00028 52 105 .. 207 259 .. 202 268 .. 0.88 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 3.5e-05 DUF5128 42 igeisrikvvd.drifvlDsaknnlfvFdkkGkfirkIgaqG 82 +++++ i v+ + + v+D+ + ++ +F+++G+f r+ g+qG FUN_000942-T1 17 FQYPHGIAVSSsGEVAVVDTCNHRIQIFNEDGEFHRAFGSQG 58 6677777777668999*************************9 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0052 DUF5128 46 srikvvddrifvlDsak.nn.lfvFdkkGkfirkIgaqGnGPgEYlqlndfiidksn 100 s + + d +fv s++ + + Fd +G+ + Ig++G G + ++ ++d+++ FUN_000942-T1 154 SYVAHSHDMYFV--SYTdGQcVKAFDSQGRSLFSIGEAGFGDSQFNRPRGVAVDQHD 208 566777888999..555477799**********************999999999876 PP == domain 3 score: 20.6 bits; conditional E-value: 1.3e-07 DUF5128 52 ddrifvlDsaknnlfvFdkkGkfirkIgaqGnGPgEYlqlndfiidksnesIyi 105 d+++v D +n++ vF+ +Gkf +k g++G+G g +++ d +i ++ +I++ FUN_000942-T1 207 HDQLLVCDGWNNRIQVFTLEGKFLHKFGSRGQGLGQLTFPVDLAIGRDG-RIFV 259 4899*****************************************9765.7776 PP >> TEN_NHL Teneurin NHL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 0.0 0.00012 0.25 140 181 .. 16 59 .. 9 66 .. 0.84 2 ? 0.4 0.0 0.16 3.4e+02 141 181 .. 64 106 .. 60 133 .. 0.57 3 ? -1.3 0.0 0.54 1.2e+03 138 167 .. 103 132 .. 77 162 .. 0.79 4 ! 6.1 0.0 0.0031 6.6 138 163 .. 193 218 .. 158 227 .. 0.84 5 ! 5.0 0.0 0.0064 14 29 48 .. 242 261 .. 233 268 .. 0.84 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00012 TEN_NHL 140 kLinPkGiavdkkGlvyfvdgta..irkvdenGiistllgsnsl 181 ++++P+Giav+++G v +vd+ + i+ +e+G + gs++ FUN_000942-T1 16 EFQYPHGIAVSSSGEVAVVDTCNhrIQIFNEDGEFHRAFGSQGI 59 6789****************975338899999999999998875 PP == domain 2 score: 0.4 bits; conditional E-value: 0.16 TEN_NHL 141 LinPkGiavdkkGlvyfvdgtair..kvdenGiistllgsnsl 181 L+ P G + d++G + ++d+ + r + ++G + +l +++l FUN_000942-T1 64 LNFPDGATFDHEGNLVLADSDNHRlsFHSQDGKVIRILSNEDL 106 5556666666666666666554441133445544444444444 PP == domain 3 score: -1.3 bits; conditional E-value: 0.54 TEN_NHL 138 eakLinPkGiavdkkGlvyfvdgtairkvd 167 + L nP G++ ++G + + g r+++ FUN_000942-T1 103 NEDLRNPWGVCTTSEGNIAVCSGGDKRQIQ 132 456888888888888888888877777665 PP == domain 4 score: 6.1 bits; conditional E-value: 0.0031 TEN_NHL 138 eakLinPkGiavdkkGlvyfvdgtai 163 ++++++P+G+avd++ + + dg + FUN_000942-T1 193 DSQFNRPRGVAVDQHDQLLVCDGWNN 218 467899****************9764 PP == domain 5 score: 5.0 bits; conditional E-value: 0.0064 TEN_NHL 29 kLlaPvalaagidGslyvgd 48 +L Pv+la+g dG ++v++ FUN_000942-T1 242 QLTFPVDLAIGRDGRIFVSE 261 4677*************987 PP >> PhoX Alkaline phosphatase PhoX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.052 1.1e+02 423 472 .. 12 58 .. 5 63 .. 0.73 2 ! 13.7 0.1 1.6e-05 0.035 400 470 .. 38 103 .. 29 105 .. 0.78 3 ? 1.7 0.0 0.076 1.6e+02 425 464 .. 103 140 .. 99 161 .. 0.82 4 ? 1.7 0.0 0.074 1.6e+02 424 468 .. 192 233 .. 176 252 .. 0.79 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.052 PhoX 423 segndlespDniavdpeGrlwiqeDgneskdellgvtaeGkvynlarnqg 472 ++++ +++p +iav+++G++ +++ n+ + ++G+ ++ qg FUN_000942-T1 12 TNHGEFQYPHGIAVSSSGEVAVVDTCNHR---IQIFNEDGEFHRAFGSQG 58 57889***************998766663...334556666666665555 PP == domain 2 score: 13.7 bits; conditional E-value: 1.6e-05 PhoX 400 kftldlflvaGdpedaeaasaessegndlespDniavdpeGrlwiqeDgneskdellgvtaeGkvynlarn 470 + + ++f + G+ ++a++ + ++ +dl+ pD+ ++d eG+l++++ n+ +l ++++Gkv + +n FUN_000942-T1 38 NHRIQIFNEDGE--FHRAFGSQGINIGDLNFPDGATFDHEGNLVLADSDNH---RLSFHSQDGKVIRILSN 103 556677777776..5556888899999****************99865544...57789999999988665 PP == domain 3 score: 1.7 bits; conditional E-value: 0.076 PhoX 425 gndlespDniavdpeGrlwiqeDgneskdellgvtaeGkv 464 ++dl++p +++ ++eG++ ++ g++ + ++eG++ FUN_000942-T1 103 NEDLRNPWGVCTTSEGNIAVCSGGDKRQI--QVFSPEGSL 140 68999****************99998654..456666665 PP == domain 4 score: 1.7 bits; conditional E-value: 0.074 PhoX 424 egndlespDniavdpeGrlwiqeDgneskdellgvtaeGkvynla 468 ++++++ p ++avd++ +l++++ n+ + t eGk + + FUN_000942-T1 192 GDSQFNRPRGVAVDQHDQLLVCDGWNNR---IQVFTLEGKFLHKF 233 6889******************777773...44578888876554 PP >> DUF5711 Family of unknown function (DUF5711) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.013 27 99 128 .. 23 50 .. 12 60 .. 0.72 2 ! 7.4 0.0 0.0015 3.1 67 133 .. 77 145 .. 72 185 .. 0.86 3 ? 4.6 0.0 0.011 23 113 154 .. 214 258 .. 207 270 .. 0.87 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.013 DUF5711 99 vsvssqGvvaavledeestyIelYdkeGee 128 ++vss+G va+v + +++I++++++Ge FUN_000942-T1 23 IAVSSSGEVAVVD--TCNHRIQIFNEDGEF 50 5678888888773..455678888888775 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0015 DUF5711 67 yvaiaDkggnkiyvfdkkgllgeietslpIek...vsvssqGvvaavledeestyIelYdkeGeelaeik 133 +++ aD++ +++ +++g++ +i + +++ v+ +s+G +a+ ++++ +I++++ eG+ l+++ FUN_000942-T1 77 NLVLADSDNHRLSFHSQDGKVIRILSNEDLRNpwgVCTTSEGNIAVCS-GGDKRQIQVFSPEGSLLMSFG 145 678999999999999999*********999987778999999998765.5777*************9875 PP == domain 3 score: 4.6 bits; conditional E-value: 0.011 DUF5711 113 deestyIelYdkeGeelaeikttmeksG...YpldialSpdgkkl 154 d+ +++I++++ eG+ l ++ ++ ++ G +p+d+a+ dg+ + FUN_000942-T1 214 DGWNNRIQVFTLEGKFLHKFGSRGQGLGqltFPVDLAIGRDGRIF 258 556799*****************99999999***********854 PP >> Vgb_lyase Virginiamycin B lyase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 3.1e-06 0.0066 13 213 .. 18 229 .. 13 267 .. 0.79 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 3.1e-06 Vgb_lyase 13 agpygitagpdgalWftlvkagrigrltadgevte.yeldtad....agptvitagpdgalWfteskahrigrittdGevtefalptadsgPfgia 103 + p gi++++ g++ + + + ri +++dge+++ + + + p t +++g+l + s++hr++ ++dG+v + ++ +P+g++ FUN_000942-T1 18 QYPHGIAVSSSGEVAVVDTCNHRIQIFNEDGEFHRaFGSQGINigdlNFPDGATFDHEGNLVLADSDNHRLSFHSQDGKVIRILSNEDLRNPWGVC 113 57999**********9999999***9*999998652443333311114577889999***************************99999******* PP Vgb_lyase 104 agpdgalWftem.nadrigrittdgev.tefelpvegafpsaitagpDgalwftlnq.anaigrittdGevteyplptee......aaPvGitaga 190 + ++g + + +i +++g++ +f p + ps+++++ D ++f + ++ + + +G+ +++++ ++ P G++ ++ FUN_000942-T1 114 TTSEGNIAVCSGgDKRQIQVFSPEGSLlMSFGDPSSRHRPSYVAHSHD--MYFVSYTdGQCVKAFDSQGR-SLFSIGEAGfgdsqfNRPRGVAVDQ 206 ******98876515667999999*996379***************999..67765550555556666665.6777765442222226799999999 PP Vgb_lyase 191 dgalWfveiaagqigrittdGei 213 ++ l + +++i t +G++ FUN_000942-T1 207 HDQLLVCDGWNNRIQVFTLEGKF 229 99999999999999999999875 PP >> TrAA12 TrAA12-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 1.7 3.5e+03 19 77 .. 20 31 .. 13 48 .. 0.57 2 ? 1.7 0.0 0.051 1.1e+02 13 41 .. 61 89 .. 49 119 .. 0.81 3 ? 7.9 0.0 0.00068 1.5 15 37 .. 195 217 .. 191 233 .. 0.80 4 ? -0.3 0.0 0.22 4.6e+02 364 378 .. 246 260 .. 235 269 .. 0.88 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.7 TrAA12 19 pRgivfDsegnLLvvdrgvGivaltlkdngegcvessktviveeeelnhGialskdgkt 77 p hGia+s++g+ FUN_000942-T1 20 P-----------------------------------------------HGIAVSSSGEV 31 3...............................................44444444432 PP == domain 2 score: 1.7 bits; conditional E-value: 0.051 TrAA12 13 angLtkpRgivfDsegnLLvvdrgvGiva 41 +++L+ p g +fD+egnL+++d+ + + FUN_000942-T1 61 IGDLNFPDGATFDHEGNLVLADSDNHRLS 89 568999999***********999874444 PP == domain 3 score: 7.9 bits; conditional E-value: 0.00068 TrAA12 15 gLtkpRgivfDsegnLLvvdrgv 37 ++++pRg+++D++++LLv d + FUN_000942-T1 195 QFNRPRGVAVDQHDQLLVCDGWN 217 6899**************99654 PP == domain 4 score: -0.3 bits; conditional E-value: 0.22 TrAA12 364 Pvglafdskgrlfvs 378 Pv la++++gr+fvs FUN_000942-T1 246 PVDLAIGRDGRIFVS 260 9************98 PP >> DUF6129 Family of unknown function (DUF6129) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 4.4e-05 0.094 20 48 .. 146 174 .. 142 178 .. 0.91 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.4e-05 DUF6129 20 dvsPryaPaltlesydlylisGasGhCle 48 d s r++P++ s+d+y++s G C+ FUN_000942-T1 146 DPSSRHRPSYVAHSHDMYFVSYTDGQCVK 174 7799***********************85 PP >> SSL_N Strictosidine synthase-like, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.085 1.8e+02 15 40 .. 59 84 .. 55 84 .. 0.85 2 ? -2.4 0.0 3 6.3e+03 39 46 .] 93 100 .. 92 100 .. 0.84 3 ? 6.9 0.0 0.0037 7.9 17 41 .. 240 264 .. 238 268 .. 0.84 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.085 SSL_N 15 ialggehGPEdiavdadGrlYtglad 40 i +g+ P ++d++G+l+ ++ d FUN_000942-T1 59 INIGDLNFPDGATFDHEGNLVLADSD 84 778888999999********999876 PP == domain 2 score: -2.4 bits; conditional E-value: 3 SSL_N 39 adGrIvRi 46 +dG+++Ri FUN_000942-T1 93 QDGKVIRI 100 79***997 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0037 SSL_N 17 lggehGPEdiavdadGrlYtgladG 41 lg+ + P d+a+++dGr++++ + G FUN_000942-T1 240 LGQLTFPVDLAIGRDGRIFVSELKG 264 66777788***********997776 PP >> Proteasome_A_N Proteasome subunit A N-terminal signature # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.7 5.7e+03 5 12 .. 41 48 .. 40 49 .. 0.84 2 ? -3.1 0.0 4.5 9.6e+03 7 14 .. 71 78 .. 70 78 .. 0.85 3 ? -2.4 0.0 2.7 5.8e+03 9 14 .. 92 97 .. 89 98 .. 0.86 4 ? 8.3 0.0 0.0012 2.5 3 15 .. 129 141 .. 129 141 .. 0.86 5 ? -1.3 0.1 1.2 2.6e+03 11 15 .. 254 258 .. 253 258 .. 0.90 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.7 Proteasome_A_N 5 lttFSPdG 12 + +F+ dG FUN_000942-T1 41 IQIFNEDG 48 679****9 PP == domain 2 score: -3.1 bits; conditional E-value: 4.5 Proteasome_A_N 7 tFSPdGRL 14 tF +G L FUN_000942-T1 71 TFDHEGNL 78 99999987 PP == domain 3 score: -2.4 bits; conditional E-value: 2.7 Proteasome_A_N 9 SPdGRL 14 S+dG++ FUN_000942-T1 92 SQDGKV 97 99**96 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0012 Proteasome_A_N 3 rslttFSPdGRLf 15 r + +FSP+G L+ FUN_000942-T1 129 RQIQVFSPEGSLL 141 5789******986 PP == domain 5 score: -1.3 bits; conditional E-value: 1.2 Proteasome_A_N 11 dGRLf 15 dGR+f FUN_000942-T1 254 DGRIF 258 9***9 PP >> FokI_cleav_dom FokI, cleavage domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 1.1 2.3e+03 60 84 .. 14 38 .. 7 50 .. 0.83 2 ? 9.2 0.1 0.00066 1.4 56 101 .. 57 100 .. 46 115 .. 0.78 3 ? -1.5 0.0 1.2 2.6e+03 64 82 .. 197 215 .. 187 261 .. 0.82 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.1 FokI_cleav_dom 60 lggsnkpdgiawdndgnfiifdtka 84 g + p gia g++ ++dt FUN_000942-T1 14 HGEFQYPHGIAVSSSGEVAVVDTCN 38 5667789***********9999965 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00066 FokI_cleav_dom 56 dgkplggsnkpdgiawdndgnfiifdtkaynkgyslagntdkvkry 101 +g +g n pdg ++d +gn+++ d+ n+ s+ + kv r FUN_000942-T1 57 QGINIGDLNFPDGATFDHEGNLVLADSD--NHRLSFHSQDGKVIRI 100 57789999****************9986..4555666666666665 PP == domain 3 score: -1.5 bits; conditional E-value: 1.2 FokI_cleav_dom 64 nkpdgiawdndgnfiifdt 82 n+p g+a d+ ++++ d FUN_000942-T1 197 NRPRGVAVDQHDQLLVCDG 215 8899999998888888775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (298 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 535 (0.0209434); expected 510.9 (0.02) Passed bias filter: 486 (0.0190252); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 2904.66 // Query: FUN_000943-T1 [L=308] Description: FUN_000943 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-23 83.0 2.2 2.3e-10 40.5 0.1 3.2 3 Mito_carr Mitochondrial carrier protein Domain annotation for each model (and alignments): >> Mito_carr Mitochondrial carrier protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.5 0.2 3.9e-14 1e-09 12 89 .. 23 112 .. 18 116 .. 0.91 2 ! 40.5 0.1 9e-15 2.3e-10 8 77 .. 139 208 .. 133 224 .. 0.88 3 ? 1.8 0.0 0.011 2.8e+02 17 54 .. 244 288 .. 236 300 .. 0.69 Alignments for each domain: == domain 1 score: 38.5 bits; conditional E-value: 3.9e-14 Mito_carr 12 GgiagaiaklvtyPldvvKtrlqlqskkskskksk............ildafkkivkeeGirglykGllpnllrvapaaaikfatyetlk 89 ++i ga+ +++t+Pl v++ +q+ ++ + s+ +++ + +i k eG++gly+Gllp++ ++++++++ ++ t+ FUN_000943-T1 23 AIILGALMTTATHPLTCVRVLMQVGHEPIAPTPSRtlfgtkvlrlpsFFQYANHIKKVEGWKGLYRGLLPRVYSSMVGTFLNSTILQTVS 112 56789*******************9999887666689999*****************************************999988876 PP == domain 2 score: 40.5 bits; conditional E-value: 9e-15 Mito_carr 8 sllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapa 77 + + ++++++a ++ +Pl vv +r+++q +++ +s++ fk+i+++eGi+g+++G++p++l+ + + FUN_000943-T1 139 ETCVQAAGKVTALVISHPLYVVSIRMMVQFVGKETIYSGLRASFKEIYENEGIAGFFSGIIPRILGEVLS 208 5556678889999**********************9999**************************99854 PP == domain 3 score: 1.8 bits; conditional E-value: 0.011 Mito_carr 17 aiaklvtyPldvvKtrlqlqskkskskksk.......ildafkki 54 +a +vtyP+ +v + +++ + + d+f+ + FUN_000943-T1 244 YVAGVVTYPFVLVTHMMIVNHVGLAAGEVPampafsgWTDCFSYL 288 57899*****99988888877766655444566555566666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (308 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 891 (0.0348796); expected 510.9 (0.02) Passed bias filter: 701 (0.0274418); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3035.08 // Query: FUN_000944-T1 [L=402] Description: FUN_000944 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-42 145.8 3.3 2.9e-42 145.2 3.3 1.2 1 PSMD12-CSN4_N PSMD12/CSN4, N-terminal 1.4e-19 70.5 0.0 4.8e-19 68.8 0.0 1.9 1 PCI PCI domain 6.5e-19 68.3 0.7 6.5e-19 68.3 0.7 1.8 2 CSN4_RPN5_eIF3a CSN4/RPN5/eIF3a helix turn helix domain 0.00043 20.5 2.3 0.00071 19.8 2.3 1.4 1 RPN7 26S proteasome subunit RPN7 0.0068 17.2 0.6 6.8 7.6 0.2 2.7 2 TPR_19 Tetratricopeptide repeat ------ inclusion threshold ------ 0.033 15.4 0.9 9.6 7.7 0.1 3.1 2 TPR_14 Tetratricopeptide repeat 0.033 14.6 0.3 0.17 12.3 0.1 2.2 2 ApoB100_C Apolipoprotein B100 C terminal 0.23 12.3 0.1 30 5.6 0.0 2.4 2 Ribonucleas_3_2 Ribonuclease III 0.24 12.1 3.5 0.21 12.3 0.7 2.4 2 TPR_12 Tetratricopeptide repeat 0.4 11.4 5.7 0.74 10.6 0.1 3.3 3 TPR_7 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> PSMD12-CSN4_N PSMD12/CSN4, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.2 3.3 1.2e-45 2.9e-42 14 217 .. 13 215 .. 3 216 .. 0.97 Alignments for each domain: == domain 1 score: 145.2 bits; conditional E-value: 1.2e-45 PSMD12-CSN4_N 14 rqasdlastkrvlvkivellseakdwellneqitlLskkrgqlkqaiqkmvqeameyldelpdeetklklietLrtvtegkifvEverArltrkla 109 +++d ++r +++ v + e e+l+ +i++ + ++++l+ ++ ++++e+++y+++++++++k + +L++++++ i++E++ A+++++la FUN_000944-T1 13 GSHKDITGKYREILEKVFKFQEPALSEALKVFIEAVVHESVSLVVSR-QVLTELCSYIPNMESMSAKNVSHFILDKLQPRAISFEEQVATIRKHLA 107 57889999999999999999999************************.************************************************ PP PSMD12-CSN4_N 110 kikeaegdieeAaeiLqelqvEty.gsmekreKvefiLeqmrlllekkDyvrakilskKiskkflkeeenedlklkyyelmirialherkyleiak 204 k++e+ ++++eAa++L ++++Et ++++ ++K+e++L++ +l+le++D v+a+++++++s + +++ +e l++ y+ +++r+ +++rk++e+a+ FUN_000944-T1 108 KMYEDCQQWREAARVLTGIPLETGqRQYSVDYKLETYLKIAQLYLEDEDPVQAEAYINRASLLQTDTK-TERLQILYKVCYARVLDYRRKFIEAAQ 202 *****************************************************************888.*************************** PP PSMD12-CSN4_N 205 kylelyetpsike 217 +y l++ + i+e FUN_000944-T1 203 RYIDLSYRTAIHE 215 *********9998 PP >> PCI PCI domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.8 0.0 1.9e-22 4.8e-19 10 83 .. 285 358 .. 281 359 .. 0.95 Alignments for each domain: == domain 1 score: 68.8 bits; conditional E-value: 1.9e-22 PCI 10 qddglaelledLrrkirernlrqlskpyssislsdlakllglsvdevEkilaklIrdgrikakIDqvngivvvs 83 q+ +a+ ++ L r ++e+nl++ sk y++i++++l +ll+++ +++E+i +++I++gr++++IDq +g+v+++ FUN_000944-T1 285 QKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPPQKAERIASQMISEGRMSGSIDQIDGVVHFE 358 5677889999**************************************************************97 PP >> CSN4_RPN5_eIF3a CSN4/RPN5/eIF3a helix turn helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 9 2.3e+04 19 24 .. 24 29 .. 23 32 .. 0.84 2 ! 68.3 0.7 2.5e-22 6.5e-19 1 41 [. 361 401 .. 361 402 .] 0.97 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 9 CSN4_RPN5_eIF3a 19 ellEKI 24 e+lEK+ FUN_000944-T1 24 EILEKV 29 89**98 PP == domain 2 score: 68.3 bits; conditional E-value: 2.5e-22 CSN4_RPN5_eIF3a 1 EvLPlWDKQIQSLCyQVNellEKIrtvePvWaakkleeQmT 41 E+LP WD+Q+Q LC+QVN+++EKI t +P+W+ak e Qm FUN_000944-T1 361 EILPSWDRQVQNLCFQVNNVIEKIETYAPEWVAKYTESQMS 401 89**************************************5 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 2.3 2.8e-07 0.00071 31 170 .. 95 240 .. 72 244 .. 0.88 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 2.8e-07 RPN7 31 gkeeirraledlaehyakigdlenAlkaye....rarekttslghkidlllnlirvgiffndwalvskylekaksliekggdwerrnrlkvyeGla 122 +e++++ ++ la+ y+++ + ++A + ++ ++ + s + k++ +l++ ++ ++ +d +++ y+++a l+ +++ + + +kv + FUN_000944-T1 95 FEEQVATIRKHLAKMYEDCQQWREAARVLTgiplETGQRQYSVDYKLETYLKIAQLYLEDEDPVQAEAYINRASLLQTDTKTERLQILYKVCYARV 190 58999999********************98333357788889999***********************************99************** PP RPN7 123 alairkfkeAakllldslstfts..telisyedvavyavlcalasldRkd 170 + +rkf eAa+ +d ++ +e +++ + a++ +++a a +R++ FUN_000944-T1 191 LDYRRKFIEAAQRYIDLSYRTAIheEERMTALKHALICTMLASAGQQRSR 240 ****************9887755778888888888888888888877776 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.0 0.0 0.0041 11 25 60 .. 100 134 .. 91 136 .. 0.86 2 ! 7.6 0.2 0.0027 6.8 27 57 .. 143 173 .. 140 183 .. 0.86 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0041 TPR_19 25 aearllLArallalgrldeAealLaalpaadpddpe 60 a +r LA+ + +++ eA ++L +p++ + + FUN_000944-T1 100 ATIRKHLAKMYEDCQQWREAARVLTGIPLETGQ-RQ 134 668899***********************9987.54 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0027 TPR_19 27 arllLArallalgrldeAealLaalpaadpd 57 +l A+++l+ ++ +Aea ++++++ + d FUN_000944-T1 143 TYLKIAQLYLEDEDPVQAEAYINRASLLQTD 173 57889*******************9988777 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.035 88 4 24 .. 103 123 .. 100 126 .. 0.89 2 ? 7.7 0.1 0.0038 9.6 2 27 .. 142 167 .. 141 183 .. 0.85 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.035 TPR_14 4 wlalarallalGdpdeAlell 24 ++ la+ ++ ++++ eA+++l FUN_000944-T1 103 RKHLAKMYEDCQQWREAARVL 123 6789***************98 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0038 TPR_14 2 eawlalarallalGdpdeAlellera 27 e +l a+++l+ dp +A+++++ra FUN_000944-T1 142 ETYLKIAQLYLEDEDPVQAEAYINRA 167 67999********************8 PP >> ApoB100_C Apolipoprotein B100 C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.3 3.3e+03 5 24 .. 21 40 .. 18 51 .. 0.79 2 ? 12.3 0.1 6.6e-05 0.17 10 31 .. 187 208 .. 177 211 .. 0.89 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.3 ApoB100_C 5 kLqelsdqlsdyyEkliaes 24 k +e+ ++++ ++E ++e+ FUN_000944-T1 21 KYREILEKVFKFQEPALSEA 40 78899999999999877776 PP == domain 2 score: 12.3 bits; conditional E-value: 6.6e-05 ApoB100_C 10 sdqlsdyyEkliaeskrLIDLs 31 + ++ dy k+i ++r IDLs FUN_000944-T1 187 YARVLDYRRKFIEAAQRYIDLS 208 78999****************9 PP >> Ribonucleas_3_2 Ribonuclease III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.029 75 67 112 .. 67 112 .. 45 118 .. 0.87 2 ? 5.6 0.0 0.012 30 62 107 .. 160 205 .. 153 218 .. 0.89 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.029 Ribonucleas_3_2 67 ayaWlkgkisieeaveilkknlddevldfsrkkeaigkalakllee 112 +y ++++s ++ + l++ + f + +i k lak++e FUN_000944-T1 67 SYIPNMESMSAKNVSHFILDKLQPRAISFEEQVATIRKHLAKMYED 112 5556678999999999999************************986 PP == domain 2 score: 5.6 bits; conditional E-value: 0.012 Ribonucleas_3_2 62 aeallayaWlkgkisieeaveilkknlddevldfsrkkeaigkala 107 aea++ +a l ++ + e ++il+k vld+ rk + ++ + FUN_000944-T1 160 AEAYINRASLLQTDTKTERLQILYKVCYARVLDYRRKFIEAAQRYI 205 8***********************************9888777665 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.7 8.4e-05 0.21 3 71 .. 100 167 .. 98 172 .. 0.85 2 ? -2.8 0.1 4.1 1.1e+04 9 27 .. 187 206 .. 178 218 .. 0.61 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 8.4e-05 TPR_12 3 atalnnlAavlrrlgrydeAlelleka.lelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqa 71 at+ +lA ++ + +++ eA + l le +r + d+ ++++ +++lyl+ +d+ +A+++ ++a FUN_000944-T1 100 ATIRKHLAKMYEDCQQWREAARVLTGIpLETGQRQYSVDY--KLETYLKIAQLYLEDEDPVQAEAYINRA 167 6666678888888888888888888876788899999998..9***********************9998 PP == domain 2 score: -2.8 bits; conditional E-value: 4.1 TPR_12 9 lAavl.rrlgrydeAlelle 27 +A vl +r++ + A+++ + FUN_000944-T1 187 YARVLdYRRKFIEAAQRYID 206 45555455555555555555 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 0.00029 0.74 4 23 .. 105 124 .. 103 126 .. 0.92 2 ? 2.3 0.1 0.13 3.3e+02 2 26 .. 144 168 .. 143 179 .. 0.80 3 ? -2.8 0.3 5.6 1.4e+04 7 25 .. 189 207 .. 188 218 .. 0.65 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00029 TPR_7 4 aLariyrklGdydeAirlye 23 La +y+ + +++eA+r+++ FUN_000944-T1 105 HLAKMYEDCQQWREAARVLT 124 59***************986 PP == domain 2 score: 2.3 bits; conditional E-value: 0.13 TPR_7 2 LsaLariyrklGdydeAirlyerlL 26 ++ +a++y +d +A+++ r+ FUN_000944-T1 144 YLKIAQLYLEDEDPVQAEAYINRAS 168 56789*************9988754 PP == domain 3 score: -2.8 bits; conditional E-value: 5.6 TPR_7 7 riyrklGdydeAirlyerl 25 r++ ++++ eA++ y l FUN_000944-T1 189 RVLDYRRKFIEAAQRYIDL 207 6666777777888888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1187 (0.046467); expected 510.9 (0.02) Passed bias filter: 755 (0.0295557); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3978.94 // Query: FUN_000945-T1 [L=609] Description: FUN_000945 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (609 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 851 (0.0333138); expected 510.9 (0.02) Passed bias filter: 462 (0.0180857); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5778.74 // Query: FUN_000946-T1 [L=242] Description: FUN_000946 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-12 47.6 2.3 8.2e-12 46.2 2.3 1.7 1 NADAR NADAR domain Domain annotation for each model (and alignments): >> NADAR NADAR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 2.3 3.2e-16 8.2e-12 1 162 [. 68 237 .. 68 238 .. 0.70 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 3.2e-16 NADAR 1 fFykeeeepygvfsnfspseftvegeeesvkleeltyptaehymmaqKallfgdeea..........aekilaakspkeakalgr........... 75 fFy+++++p++ fsnf + + +++ee +p++ehy++ K f ++ ++k ++++ k + gr FUN_000946-T1 68 FFYSRSRSPHCLFSNFFEVD---------IEMEEGVFPSVEHYFQGMK---FIPKDRkrfmkggdldQRKATKTSNSKVEMEKGRfaksagsksgs 151 7999999**********444.........4455667************...443332236777766544434444444444456677777779988 PP NADAR 76 .....kvrkfdeedWeevkeevveegnlaKFtqneelrelLlaTgdreLveasp..kDriWGiGlkaddaaenrekwkGkNlLGkaLmevReeL 162 + ++ +ev + +++++ +KF+++ ++++Ll+Tg+ L++ k ++W ++ ++ + GkN +G++Lm+vR+ L FUN_000946-T1 152 akynlT--LATDGLDREVAKCRMKRALEKKFEKE-PFKSALLETGKTRLIHIPLrgKTDFWTGK--RH---KETGEIVGKNTMGELLMKVRDAL 237 877542..22344556688888*********875.69*************97651155689654..22...3445556**************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (242 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 551 (0.0215698); expected 510.9 (0.02) Passed bias filter: 412 (0.0161284); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2440.49 // Query: FUN_000948-T1 [L=438] Description: FUN_000948 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-42 144.7 0.3 3e-41 142.5 0.3 1.8 1 His_Phos_2 Histidine phosphatase superfamily (branch 2) ------ inclusion threshold ------ 0.17 13.1 0.1 0.45 11.7 0.1 1.7 1 EphA2_TM Ephrin type-A receptor 2 transmembrane domain 0.29 11.6 0.9 11 6.5 0.2 2.6 2 ETRAMP Malarial early transcribed membrane protein (ETRA 0.35 11.9 0.9 34 5.5 0.0 2.3 2 SIT SHP2-interacting transmembrane adaptor protein, S 0.56 10.5 1.8 1.1 9.6 1.8 1.4 1 TM_ErbB1 Epidermal growth factor receptor transmembrane-ju Domain annotation for each model (and alignments): >> His_Phos_2 Histidine phosphatase superfamily (branch 2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 142.5 0.3 5.8e-45 3e-41 1 353 [. 30 326 .. 30 327 .. 0.93 Alignments for each domain: == domain 1 score: 142.5 bits; conditional E-value: 5.8e-45 His_Phos_2 1 eleqvqvvsRHGdRtPtqkkkkeveslifkllselagslegklsflgtyrkeklqytlkwggltpaGrkqaeelGrqfrqrYv.eLlrneltqkdl 95 el++++vv RHGdR+P +++k ++ + ++ ++g+lt++G+kq + lG+ +r rYv +L+++++ ++ FUN_000948-T1 30 ELRMANVVYRHGDRSPVSGFK-------------------TDIHMN--------FWPQGLGQLTQSGMKQEFILGQFLRDRYVdKLINSSYRFSEV 98 799*****************5...................566666........999**********************************99*** PP His_Phos_2 96 kirasseeRviaSAeafaeGllgaegvdkdksllddsnvakviideekkalanlllagyescpafesiknakrvdealkklkkdlleniakrlskl 191 ++r+s+ +R i+SA+ + Gl++++g+++ ++ld+++v+++++++ +++ ll++++ +cp+ +++++ +++++ + ++++ ++ + +l FUN_000948-T1 99 YVRSSDRDRCIMSAQTQLNGLYPPHGKQVWRPNLDWQPVGVHVVPA---NEDYLLRPYDYNCPRLFEVLEKSKQEPEYVNTANKYKDDLS--YISL 189 **********************************************...99**************9988888889999999999999999..5566 PP His_Phos_2 192 lpgetnltaddvwslldkcffetnkadlspfcdlfte.edllhneylkdleelyglygignelkktiGgpllnellarlendlqaekeatfprdak 286 g + + + ++ +d f+e+ ++ ++d+ t+ + ++ + ++ + ++ g+e +k Gg l+ e +++++ + +++ k FUN_000948-T1 190 HAGG-SYSLSNMYQVYDTLFCEKT--HNLSLPDWATNgTIWEDMRNMNNFGLMWMF--KGQEKAKLTGGSLVGEFIKNMKAHREPTS-------KK 273 5666.89999************99..99******9999*************98888..899999****************9999999.......9* PP His_Phos_2 287 lylyftHDttiasllsaLglfdelekesklkvldslkasgevpyaarlvfElyec..sseedryvrlll 353 ly+y++HDtt+++llsaL lfd +++ y++++++Ely++ +++++ vr+ + FUN_000948-T1 274 LYIYSAHDTTVVALLSALKLFDGIQPA----------------YSSAVMVELYSDpdDHNKNLTVRISY 326 **********************77777................***********865566669999887 PP >> EphA2_TM Ephrin type-A receptor 2 transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 8.7e-05 0.45 3 35 .. 387 419 .. 384 429 .. 0.65 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.7e-05 EphA2_TM 3 gavagglvllvvvvvvlivrrrrkkrskaeqdy 35 ++v+++l+llv+++++ ++r+r+++ +++ + y FUN_000948-T1 387 AVVTAVLLLLVLLLCINFCRKRCCRPQRNLTIY 419 345555555566666677777999888877666 PP >> ETRAMP Malarial early transcribed membrane protein (ETRAMP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.034 1.8e+02 44 69 .. 265 290 .. 255 294 .. 0.77 2 ? 6.5 0.2 0.0022 11 3 27 .. 389 413 .. 389 433 .. 0.76 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.034 ETRAMP 44 lekkkkkkkiiiiSsiaaglallial 69 + + kk++i+S+ +++++l+ + FUN_000948-T1 265 AHREPTSKKLYIYSAHDTTVVALLSA 290 55567889999999999999988765 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0022 ETRAMP 3 itkvlalfaiLliinllvpclcnnn 27 +t vl+l+ +Ll+in++ + c + FUN_000948-T1 389 VTAVLLLLVLLLCINFCRKRCCRPQ 413 67899************88888754 PP >> SIT SHP2-interacting transmembrane adaptor protein, SIT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.0067 34 82 108 .. 164 190 .. 139 194 .. 0.86 2 ? 4.5 0.3 0.013 67 4 24 .. 387 407 .. 384 425 .. 0.79 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0067 SIT 82 aqrsqneveyvtmaplpeeeisYasLs 108 ++s++e eyv++a ++++sY sL+ FUN_000948-T1 164 LEKSKQEPEYVNTANKYKDDLSYISLH 190 5789999******************97 PP == domain 2 score: 4.5 bits; conditional E-value: 0.013 SIT 4 plilallLlllvaasllawre 24 +++a+lLll + + + ++r+ FUN_000948-T1 387 AVVTAVLLLLVLLLCINFCRK 407 678899999998888888876 PP >> TM_ErbB1 Epidermal growth factor receptor transmembrane-juxtamembrane segment # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 1.8 0.00021 1.1 2 25 .. 385 408 .. 384 414 .. 0.91 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00021 TM_ErbB1 2 aaGVVGGlLllvilaLvifvllRR 25 a +VV ++Lll++l L+i ++ +R FUN_000948-T1 385 AFAVVTAVLLLLVLLLCINFCRKR 408 679****************99888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (438 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 848 (0.0331963); expected 510.9 (0.02) Passed bias filter: 634 (0.0248189); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.41s 00:00:00.75 Elapsed: 00:00:00.43 # Mc/sec: 4106.27 // Query: FUN_000949-T1 [L=200] Description: FUN_000949 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.054 13.9 0.2 0.092 13.1 0.2 1.3 1 RVT_1 Reverse transcriptase (RNA-dependent DNA polymerase 0.11 13.0 0.2 1.3 9.6 0.0 2.3 2 DUF7083 Domain of unknown function (DUF7083) Domain annotation for each model (and alignments): >> RVT_1 Reverse transcriptase (RNA-dependent DNA polymerase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.2 7.2e-06 0.092 86 152 .. 4 85 .. 2 90 .. 0.79 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 7.2e-06 RVT_1 86 tafkvpsk.liksll....rvngeeegryewkglpqGlvlSPllfqlfmdellrelrkra..........evtllvYaDDil 152 t f++++ l ++l v+ ++ + + +p+G + +Pll+ lf++ + ++ ++ ++ +Y+DD++ FUN_000949-T1 4 TYFSCRELcLAIDFLidniYVRFGSSVFRQVIAIPMGTNSAPLLADLFLHTFEYDFMVKTmksditkaiqFSNTFRYIDDLF 85 667777556333333465433444488999999***********************999999*****99989999*****96 PP >> DUF7083 Domain of unknown function (DUF7083) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 0.062 7.9e+02 63 88 .. 61 86 .. 46 88 .. 0.66 2 ? 9.6 0.0 0.0001 1.3 19 42 .. 170 193 .. 161 196 .. 0.89 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.062 DUF7083 63 dsirdvedieevkfedtvkaLkklFg 88 ++++++ ++ ++f++t + +++lF FUN_000949-T1 61 VKTMKSDITKAIQFSNTFRYIDDLFS 86 33444444567999999999999997 PP == domain 2 score: 9.6 bits; conditional E-value: 0.0001 DUF7083 19 ektFkkWyaRyeevftedgkeLse 42 tF+k ++R+ ++ + g++L e FUN_000949-T1 170 LRTFTKFFNRHGLIVVKYGATLRE 193 579*******************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (200 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 651 (0.0254844); expected 510.9 (0.02) Passed bias filter: 492 (0.0192601); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.42s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 2048.29 // Query: FUN_000950-T1 [L=308] Description: FUN_000950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-28 100.3 23.1 6.5e-26 91.8 23.1 2.0 1 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.8 23.1 2.5e-30 6.5e-26 6 260 .] 3 243 .. 1 243 [. 0.86 Alignments for each domain: == domain 1 score: 91.8 bits; conditional E-value: 2.5e-30 xxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 6 ilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevl...CklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 +++i++ +k+lr+++ +++++L+vaDll++++++ +++v +++++++ +l ++++ ++ ++l+as ++++a+s Y+aI +p++yk+i FUN_000950-T1 3 LYTIYKdpHKSLRSASGYLIVSLSVADLLLGVFIVSIVVVRDVYRSQQLSMPFLgifKAVIHTVYATTLLASSYTIIAMSATCYVAINQPMEYKTI 98 56666655899*****************************99987766555444332678888999999*************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx... RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks... 189 t +r +++i+v Wv++++ s++p+++ + + +y+++++ p ++++v+yv+++r++ ++ ++ ++ FUN_000950-T1 99 ITTKRIKIYIAVLWVMSFATSVLPVIGLSKE------------------------TYIMIYLHTHATFPAILLTVIYVKVFRAVARRTREFQQsgy 170 **************************66432........................24444444445559**************9998888777676 PP ..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ..kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 +ks ++er ++ +++++++f ++++P i+l l ++++ c+++ + + + + + l ++ns++NP++Y FUN_000950-T1 171 nkMVAKSLERERNMTVAVITILALFYITYMPQYITLHLFYFCNPCQRSVIFHEIDVALSRLLFLNSAINPFVY 243 664556677788************************************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (308 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1174 (0.0459581); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3066.52 // Query: FUN_000951-T1 [L=85] Description: FUN_000951 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (85 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 404 (0.0158152); expected 510.9 (0.02) Passed bias filter: 246 (0.00963006); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 875.52 // Query: FUN_000952-T1 [L=284] Description: FUN_000952 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-22 78.9 21.8 1.2e-11 45.1 7.4 2.0 2 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.1 7.4 4.7e-16 1.2e-11 26 127 .. 1 105 [. 1 108 [. 0.84 2 ! 41.8 5.9 4.7e-15 1.2e-10 151 260 .] 105 219 .. 101 219 .. 0.89 Alignments for each domain: == domain 1 score: 45.1 bits; conditional E-value: 4.7e-16 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 26 LavaDllvlllvlpfalvyallegdwvfgevl...CklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkrralvlilvvWvlalllsl 118 ++vaDll++++++ ++ v ++++ ++ +l +++ + ++l++s +++ta++ Y+aI +p++yk+i t +r +++i+v Wv++++ + FUN_000952-T1 1 MSVADLLLGVFTVSVVGVRDVYRLQQLSMPFLgifKAVIQTVSATTLLVSSYTITAMAATCYVAINQPMEYKTIITTKRIKIYIAVLWVMSFATCA 96 589*******999999988887666665555511155555566667789*********************************************** PP xxxxxxxxx RF 7tm_1 119 ppllfsgtk 127 +p+++ + + FUN_000952-T1 97 LPVIGLSEE 105 ***988765 PP == domain 2 score: 41.8 bits; conditional E-value: 4.7e-15 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 151 vsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklveta 241 ++y+++++ p ++++v+yv+++r++ ++ ++ ++ +ks ++er ++ +++++++f ++++P i+l l ++++ c+++ + + + FUN_000952-T1 105 ETYIMIYLHTHATFPAILLTVIYVKVFRAVARRTREFQQsgynkMVAKSLERERNMTVAVITILALFYITYMPQYITLHLFYFCNPCQRSIIFHEI 200 56777777777888****************999888777676664556677788****************************************** PP xxxxxxxxxxxxxxxxxxx RF 7tm_1 242 llitlllayvnsclNPiiY 260 + + l ++ns++NP++Y FUN_000952-T1 201 DVALSRLLFLNSAINPFVY 219 ******************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (284 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1068 (0.0418086); expected 510.9 (0.02) Passed bias filter: 477 (0.0186729); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2755.23 // Query: FUN_000953-T1 [L=150] Description: FUN_000953 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-25 88.8 0.1 8.5e-25 88.4 0.1 1.1 1 Usp Universal stress protein family ------ inclusion threshold ------ 0.065 13.0 0.0 0.075 12.8 0.0 1.2 1 HpcH_HpaI HpcH/HpaI aldolase/citrate lyase Domain annotation for each model (and alignments): >> Usp Universal stress protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 88.4 0.1 6.6e-29 8.5e-25 5 141 .] 8 147 .. 5 147 .. 0.86 Alignments for each domain: == domain 1 score: 88.4 bits; conditional E-value: 6.6e-29 Usp 5 IlVavDgseeskkAlewAaelakargaelillhVvdpeasgaasaa...deseeeeeaeleeaeaealaaeaaaeaggvkvevvvvvgdpaeeile 97 +l+avD+ e+s+kA++w ++ ++++ li+l+ + +++a +e ++ +e++e++ ++ ++++e ++ + +v+v+ g+++e+i + FUN_000953-T1 8 VLLAVDECEHSEKAFDWYLDHVHKDDNSLIVLYCHEKLDPPALLHSqhsEEWKQTMRDHEEKKERVIEKYKTKCENKKLTAKVKVEFGKAGETIHR 103 89********************************987777766554000444445555555555555559************************** PP Usp 98 vaeeedadliVmGsrgrsglsrlllGSvsekvlrhapcpVlvvr 141 +ae+e++ iVmG r +s+l+r llG vs++v++h+++pV+ v+ FUN_000953-T1 104 IAEQEKVHFIVMGGRELSTLRRTLLGGVSDYVIKHTQIPVVYVP 147 ****************************************9886 PP >> HpcH_HpaI HpcH/HpaI aldolase/citrate lyase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 5.9e-06 0.075 103 156 .. 60 122 .. 26 133 .. 0.82 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 5.9e-06 HpcH_HpaI 103 vslirepekgirg.........enketrllaqiESaegvlnaeeIaavegvdgialGaeDlva 156 ++ +r +e+ + enk+++ +++E +++ + +++Ia+ e+v i++G l++ FUN_000953-T1 60 KQTMRDHEEKKERviekyktkcENKKLTAKVKVEFGKAGETIHRIAEQEKVHFIVMGGRELST 122 45555555433335777777779**********************************999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (150 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2194 (0.0858876); expected 510.9 (0.02) Passed bias filter: 1039 (0.0406733); expected 510.9 (0.02) Passed Vit filter: 93 (0.00364063); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1472.01 // Query: FUN_000954-T1 [L=131] Description: FUN_000954 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1312 (0.0513603); expected 510.9 (0.02) Passed bias filter: 650 (0.0254453); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1299.49 // Query: FUN_000955-T1 [L=80] Description: FUN_000955 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.074 14.0 0.2 0.091 13.7 0.2 1.2 1 WGG Pre-rRNA-processing protein TSR2 Domain annotation for each model (and alignments): >> WGG Pre-rRNA-processing protein TSR2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.2 3.6e-06 0.091 14 76 .. 5 66 .. 4 70 .. 0.83 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.6e-06 WGG 14 aLqlavengwGGpdsaekrdwlagavvdlfkenkeldaeeleelLlqvmedeFdvvveDgSae 76 +L++av+ ++G ++s e + +++a +d +k k+++ l+ +++++++ ++++e +S+e FUN_000955-T1 5 KLEIAVQMKMGNQHSLEEENCFVDAEHDRMKGMKNINLSVLHLTIKEIVS-IASMECETESTE 66 69****************************99999999999999999884.345666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (80 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 960 (0.0375807); expected 510.9 (0.02) Passed bias filter: 530 (0.0207477); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 811.79 // Query: FUN_000956-T1 [L=549] Description: FUN_000956 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-26 93.4 8.6 6.2e-26 91.6 8.6 2.1 1 Phospholip_A2_1 Phospholipase A2 ------ inclusion threshold ------ 0.21 12.7 0.1 0.77 10.9 0.0 1.9 2 DUF4429 Domain of unknown function (DUF4429) Domain annotation for each model (and alignments): >> Phospholip_A2_1 Phospholipase A2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.6 8.6 4.9e-30 6.2e-26 2 107 .. 432 539 .. 431 542 .. 0.80 Alignments for each domain: == domain 1 score: 91.6 bits; conditional E-value: 4.9e-30 Phospholip_A2_1 2 lqlekmikcvtgkeallsyesYGcycglggkgtpvdatdrCClahdcCyeklkkkgckepklekykvsvskke.itckse....kkslcekqlC 90 + +++mi c+tg+ ++ ++ YGc+cglgg+gtpvd +drCC+ahd Cy++l++ c +++ +y + +s+++ + c+ +c+++lC FUN_000956-T1 432 FGFRRMIDCATGR-SAWDFLGYGCWCGLGGRGTPVDGVDRCCKAHDICYDNLSS-VC-PHTIMTYIMPYSTRScTSCEPVsyywFWGNCRHNLC 522 679**********.9*************************************66.88.444444444444433144544344446678****** PP Phospholip_A2_1 91 eCDkaaaeClakatynk 107 CD +aa+C+a++++++ FUN_000956-T1 523 VCDATAARCFAQQSFSE 539 ************99987 PP >> DUF4429 Domain of unknown function (DUF4429) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 6e-05 0.77 20 81 .. 140 201 .. 134 213 .. 0.90 2 ? -3.2 0.0 1.5 1.9e+04 67 79 .. 293 305 .. 282 310 .. 0.69 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 6e-05 DUF4429 20 akraaGertiplsaiagVewepgkglnGyLrlvlregadplaeaaggklppkkDpytlglek 81 k ++G+r++ l+ i+ + + k +nG+ r + r+ + ++++++++++++D tl+l+ FUN_000956-T1 140 NKASKGTRRFRLAPIRPLVLDEFKMRNGVARRKWRQDSHGVQQTLSESTDQNCDTKTLSLDD 201 5779******************************************************8764 PP == domain 2 score: -3.2 bits; conditional E-value: 1.5 DUF4429 67 klppkkDpytlgl 79 +++++ Dp +l FUN_000956-T1 293 ETEKENDPKCLQK 305 5677889999954 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (549 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 745 (0.0291642); expected 510.9 (0.02) Passed bias filter: 407 (0.0159327); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5400.03 // Query: FUN_000957-T1 [L=1542] Description: FUN_000957 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.7 10.4 4.3 2.8 8.4 0.2 2.6 2 ADD_DNMT3 DNMT3, cysteine rich ADD domain, GATA1-like zinc f 9.2 7.0 9.4 1.4 9.6 4.3 2.4 2 DUF7630 Domain of unknown function (DUF7630) Domain annotation for each model (and alignments): >> ADD_DNMT3 DNMT3, cysteine rich ADD domain, GATA1-like zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.6 0.018 2.3e+02 30 45 .. 112 127 .. 104 130 .. 0.79 2 ? 8.4 0.2 0.00022 2.8 36 52 .. 1059 1075 .. 1058 1077 .. 0.91 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.018 ADD_DNMT3 30 veHPLFeGglClkCke 45 +H F+G+l kCk FUN_000957-T1 112 AQHLRFDGSLSKKCKM 127 58999*********96 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00022 ADD_DNMT3 36 eGglClkCkenfletly 52 +G +C kC+e f etl+ FUN_000957-T1 1059 DGIMCGKCREGFSETLF 1075 589*************9 PP >> DUF7630 Domain of unknown function (DUF7630) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.2 0.62 7.9e+03 26 34 .. 603 611 .. 603 617 .. 0.77 2 ? 9.6 4.3 0.00011 1.4 14 43 .. 1052 1080 .. 1048 1085 .. 0.89 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 0.62 DUF7630 26 aeCkkGYtn 34 +eC++G+ FUN_000957-T1 603 SECAQGFVI 611 69****975 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00011 DUF7630 14 gkCaegmtgyLCaeCkkGYtnnfskgslCt 43 + C ++g +C++C++G++++ ++C+ FUN_000957-T1 1052 NGCYGNRDGIMCGKCREGFSETLFS-TRCK 1080 78*****************999875.8885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1542 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1252 (0.0490115); expected 510.9 (0.02) Passed bias filter: 511 (0.0200039); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.49u 0.43s 00:00:00.92 Elapsed: 00:00:00.44 # Mc/sec: 13989.66 // Query: FUN_000958-T1 [L=116] Description: FUN_000958 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 593 (0.0232139); expected 510.9 (0.02) Passed bias filter: 357 (0.0139753); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1150.23 // Query: FUN_000959-T1 [L=1210] Description: FUN_000959 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-67 223.2 114.2 1.6e-11 44.3 7.5 9.6 9 Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B rec 9.5e-24 84.4 2.4 1.8e-23 83.5 2.4 1.5 1 F5_F8_type_C F5/8 type C domain 1.1e-13 51.8 93.0 0.26 12.2 0.8 16.2 16 TNFR_c6 TNFR/NGFR cysteine-rich region 1.7e-08 35.2 111.4 0.041 14.8 2.6 11.5 11 DUF8003 Domain of unknown function (DUF8003) 7e-06 26.3 127.0 0.014 15.7 0.8 12.1 12 NCD3G Nine Cysteines Domain of family 3 GPCR 9.7e-05 22.9 0.0 0.0003 21.4 0.0 1.8 1 SEA SEA domain 0.00018 22.5 1.3 0.00055 21.0 1.3 1.9 1 F5_F8_type_C_2 NedA-like, galactose-binding domain ------ inclusion threshold ------ 0.033 14.6 129.0 0.039 14.4 4.3 14.0 15 TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like 0.14 12.8 0.1 0.27 11.9 0.1 1.4 1 DUF3792 Protein of unknown function (DUF3792) 0.19 12.2 0.0 39 4.8 0.0 2.5 2 HU-CCDC81_bac_1 CCDC81-like prokaryotic HU domain 1 Domain annotation for each model (and alignments): >> Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 5.1 0.00052 1.3 9 40 .. 368 398 .. 362 404 .. 0.79 2 ! 35.5 2.7 3.6e-12 9.3e-09 1 48 [] 424 473 .. 424 473 .. 0.91 3 ! 34.9 2.6 5.4e-12 1.4e-08 1 48 [] 480 529 .. 480 529 .. 0.98 4 ! 30.3 8.7 1.5e-10 3.8e-07 1 48 [] 535 582 .. 535 582 .. 0.99 5 ! 32.2 4.5 3.9e-11 9.9e-08 1 48 [] 589 638 .. 589 638 .. 0.96 6 ! 31.4 7.8 6.9e-11 1.8e-07 1 48 [] 644 691 .. 644 691 .. 0.99 7 ! 33.1 5.5 2e-11 5.2e-08 1 48 [] 698 747 .. 698 747 .. 0.97 8 ! 44.3 7.5 6.2e-15 1.6e-11 1 48 [] 753 800 .. 753 800 .. 0.99 9 ! 22.5 6.6 4.1e-08 0.0001 3 35 .. 809 843 .. 807 851 .. 0.89 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00052 Ephrin_rec_like 9 etCipCprgtYqpeegqlsClaCPlgtttkst 40 C+ Cp +++ ++ ++ C++CP+gt+ s+ FUN_000959-T1 368 FVCSTCPTNQFY-NITAQVCEKCPPGTFASSR 398 56*********6.577778*******987665 PP == domain 2 score: 35.5 bits; conditional E-value: 3.6e-12 Ephrin_rec_like 1 GtysnegletCipCprgtYqp..eegqlsClaCPlgtttkstgatsksdC 48 G+ ++ ++ +C+ Cp++tYq+ + + +C++CP + t+ +ga+++++C FUN_000959-T1 424 GKHVDGKSWMCEWCPMDTYQNssTKVNPDCTPCPGEKKTRFPGAQDVTEC 473 6667778889***********87888999********************* PP == domain 3 score: 34.9 bits; conditional E-value: 5.4e-12 Ephrin_rec_like 1 GtysnegletCipCprgtYqp..eegqlsClaCPlgtttkstgatsksdC 48 Gty+n + tC Cp g+Y + + +l C++C+ + t+ tg++ +sdC FUN_000959-T1 480 GTYLNISSGTCFKCPVGSYMDvdSHVFLRCKSCGGKKITQATGSKTISDC 529 9********************8899999********************** PP == domain 4 score: 30.3 bits; conditional E-value: 1.5e-10 Ephrin_rec_like 1 GtysnegletCipCprgtYqpeegqlsClaCPlgtttkstgatsksdC 48 G+++n+ ++ C++C+ g Yq+e q +C+ C +g tt g+ sdC FUN_000959-T1 535 GSFYNSSSKSCSLCREGKYQDEVNQDTCKDCDRGKTTLDHGTNTSSDC 582 99********************************************** PP == domain 5 score: 32.2 bits; conditional E-value: 3.9e-11 Ephrin_rec_like 1 GtysnegletCipCprgtYqp..eegqlsClaCPlgtttkstgatsksdC 48 G+y+n+ e C Cp +tY + + ++++C+aC++++ t tg++++s+C FUN_000959-T1 589 GQYLNDSDEACLDCPFNTYMDnaKHRSKECKACGPNQITFATGTSNISQC 638 99*******************66778999********************* PP == domain 6 score: 31.4 bits; conditional E-value: 6.9e-11 Ephrin_rec_like 1 GtysnegletCipCprgtYqpeegqlsClaCPlgtttkstgatsksdC 48 Gt++n++ +C+ Cp+gt+q++ g+ +C+ C +g tt g+ sdC FUN_000959-T1 644 GTFLNKTVSQCQRCPKGTFQDQPGRDTCKDCDRGKTTLDYGTNTSSDC 691 9*********************************************** PP == domain 7 score: 33.1 bits; conditional E-value: 2e-11 Ephrin_rec_like 1 GtysnegletCipCprgtYqp..eegqlsClaCPlgtttkstgatsksdC 48 G+y+n+ e C Cp +tY + + ++++C+aC++++ t tg++++s+C FUN_000959-T1 698 GQYLNDSDEACLDCPFNTYMDsaKHRSKECKACGPNQITNATGTSNISQC 747 99******************97788999********************** PP == domain 8 score: 44.3 bits; conditional E-value: 6.2e-15 Ephrin_rec_like 1 GtysnegletCipCprgtYqpeegqlsClaCPlgtttkstgatsksdC 48 Gt++n++ +C+ Cp+gt+q++ gq +C++CP +++t+ +g ++ks C FUN_000959-T1 753 GTFLNKTVSQCQRCPKGTFQDQPGQDKCTQCPDTMSTDNSGQWNKSAC 800 9**********************************************9 PP == domain 9 score: 22.5 bits; conditional E-value: 4.1e-08 Ephrin_rec_like 3 ysnegletCipCprgtYqp..eegqlsClaCPlgt 35 ++++ ++C pC+ gtYq+ + +++sC+ CP+++ FUN_000959-T1 809 FYDSSDNRCKPCSYGTYQEseNHQSTSCKVCPRQG 843 789999*************98999********875 PP >> F5_F8_type_C F5/8 type C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.5 2.4 7.2e-27 1.8e-23 1 127 [] 974 1102 .. 974 1102 .. 0.87 Alignments for each domain: == domain 1 score: 83.5 bits; conditional E-value: 7.2e-27 F5_F8_type_C 1 qitasssesgeg.paaaaldGnkntaWssssnddk.qwlqvdLgkekkitgvvlqgrqdggngrvksykieysddgenWtevkd...ekv.kgn 88 qita ++ ++ p + +l+ n + +W ++ + + ++lq+d++++ +itgv +qg + n +vk+yk+++sddg++W ++ + +++ +gn FUN_000959-T1 974 QITALNY-LKNYePYEGRLNINGGRGWQAEYTRKMkEYLQIDFKRKVNITGVATQGQSTS-NLFVKQYKLSTSDDGKKWIKYTEngtSQMlNGN 1065 5677777.34444666677744499***88888878********************8777.***********************8764448*** PP F5_F8_type_C 89 sdnstpvtntfdkpvkaryvrlvptswnggngialraEl 127 d++t+v+n++ +++++ry+r+ p++wn++ i +r+E+ FUN_000959-T1 1066 QDSTTVVRNNLATSITTRYIRFLPQTWNER--IFMRVEV 1102 ****************************99..*999996 PP >> TNFR_c6 TNFR/NGFR cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 1.5 0.0037 9.4 1 28 [. 373 396 .. 373 408 .. 0.76 2 ? 5.6 1.2 0.012 30 1 23 [. 437 458 .. 437 467 .. 0.77 3 ! 9.5 0.1 0.00071 1.8 1 18 [. 477 493 .. 477 495 .. 0.95 4 ! 7.1 0.4 0.0042 11 1 27 [. 493 518 .. 493 529 .. 0.80 5 ! 5.9 0.2 0.0095 24 1 19 [. 532 549 .. 532 551 .. 0.81 6 ! 8.6 2.9 0.0014 3.6 1 34 [. 548 578 .. 548 583 .. 0.73 7 ? 2.3 0.1 0.13 3.3e+02 1 18 [. 586 602 .. 586 603 .. 0.91 8 ! 12.2 0.8 0.0001 0.26 1 31 [. 602 631 .. 602 636 .. 0.86 9 ! 11.4 0.1 0.00019 0.48 1 30 [. 641 666 .. 641 667 .. 0.85 10 ! 8.4 2.5 0.0015 3.9 1 19 [. 657 675 .. 657 692 .. 0.81 11 ? 2.3 0.1 0.12 3.2e+02 1 18 [. 695 711 .. 695 713 .. 0.91 12 ! 12.1 1.0 0.00011 0.29 1 32 [. 711 741 .. 711 744 .. 0.85 13 ! 11.1 0.1 0.00023 0.6 1 29 [. 750 774 .. 750 775 .. 0.83 14 ! 9.6 4.4 0.00066 1.7 1 24 [. 766 786 .. 766 802 .. 0.71 15 ! 6.5 0.7 0.0063 16 1 19 [. 804 821 .. 804 822 .. 0.93 16 ! 12.0 5.6 0.00012 0.31 1 31 [. 820 850 .. 820 853 .. 0.85 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0037 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvvl 28 Cp +++++ + + C +Cppg++ FUN_000959-T1 373 CPTNQFYNIT----AQVCEKCPPGTFAS 396 9999999998....55589999998764 PP == domain 2 score: 5.6 bits; conditional E-value: 0.012 TNFR_c6 1 CppgtYtdssnglkClpCtvCpp 23 Cp +tY++ss++ Ct+Cp+ FUN_000959-T1 437 CPMDTYQNSSTKV-NPDCTPCPG 458 ******9999988.555666665 PP == domain 3 score: 9.5 bits; conditional E-value: 0.00071 TNFR_c6 1 CppgtYtdssnglkClpC 18 Cp+gtY + s+g+ C++C FUN_000959-T1 477 CPNGTYLNISSGT-CFKC 493 ************9.**** PP == domain 4 score: 7.1 bits; conditional E-value: 0.0042 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvv 27 Cp g+Y+d +++ l+C++C + + FUN_000959-T1 493 CPVGSYMDVDSHV-FLRCKSCGGKKIT 518 *************.8999999765554 PP == domain 5 score: 5.9 bits; conditional E-value: 0.0095 TNFR_c6 1 CppgtYtdssnglkClpCt 19 C +g++++ss+++ C C+ FUN_000959-T1 532 CMKGSFYNSSSKS-CSLCR 549 99****9999888.77775 PP == domain 6 score: 8.6 bits; conditional E-value: 0.0014 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvvlqpCtpt 34 C++g+Y+d+ n+ +C + C+ g +l + t t FUN_000959-T1 548 CREGKYQDEVNQDTC---KDCDRGKTTLDHGTNT 578 ***********9955...5566666665555555 PP == domain 7 score: 2.3 bits; conditional E-value: 0.13 TNFR_c6 1 CppgtYtdssnglkClpC 18 C g+Y + s + Cl C FUN_000959-T1 586 CGLGQYLNDSDEA-CLDC 602 999***9999888.***9 PP == domain 8 score: 12.2 bits; conditional E-value: 0.0001 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvvlqpC 31 Cp +tY+d+ ++ + C+ C p+q + + FUN_000959-T1 602 CPFNTYMDNAKHR-SKECKACGPNQITFATG 631 999*******999.*********99885544 PP == domain 9 score: 11.4 bits; conditional E-value: 0.00019 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvvlqp 30 C++gt+ +++ ++ C++Cp+g+++ qp FUN_000959-T1 641 CRKGTFLNKTVSQ----CQRCPKGTFQDQP 666 ********99887....7888999988776 PP == domain 10 score: 8.4 bits; conditional E-value: 0.0015 TNFR_c6 1 CppgtYtdssnglkClpCt 19 Cp+gt++d++++ +C+ C FUN_000959-T1 657 CPKGTFQDQPGRDTCKDCD 675 **********988787774 PP == domain 11 score: 2.3 bits; conditional E-value: 0.12 TNFR_c6 1 CppgtYtdssnglkClpC 18 C g+Y + s + Cl C FUN_000959-T1 695 CGLGQYLNDSDEA-CLDC 711 999***9999888.***9 PP == domain 12 score: 12.1 bits; conditional E-value: 0.00011 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvvlqpCt 32 Cp +tY+ds ++ + C+ C p+q + + t FUN_000959-T1 711 CPFNTYMDSAKHR-SKECKACGPNQITNATGT 741 999*******999.**********99854444 PP == domain 13 score: 11.1 bits; conditional E-value: 0.00023 TNFR_c6 1 CppgtYtdssnglkClpCtvCppgqvvlq 29 C++gt+ +++ ++ C++Cp+g+++ q FUN_000959-T1 750 CRKGTFLNKTVSQ----CQRCPKGTFQDQ 774 ********99887....688899988766 PP == domain 14 score: 9.6 bits; conditional E-value: 0.00066 TNFR_c6 1 CppgtYtdssnglkClpCtvCppg 24 Cp+gt++d++++ +Ct+Cp+ FUN_000959-T1 766 CPKGTFQDQPGQD---KCTQCPDT 786 **********988...66777763 PP == domain 15 score: 6.5 bits; conditional E-value: 0.0063 TNFR_c6 1 CppgtYtdssnglkClpCt 19 C + +++dss ++ C+pC+ FUN_000959-T1 804 CGKEEFYDSSDNR-CKPCS 821 9999*****9999.****8 PP == domain 16 score: 12.0 bits; conditional E-value: 0.00012 TNFR_c6 1 CppgtYtdssnglkClpCtvCpp.gqvvlqpC 31 C +gtY++s+n++ ++C+vCp g v ++C FUN_000959-T1 820 CSYGTYQESENHQ-STSCKVCPRqGAVDFKQC 850 9************.*******76477767776 PP >> DUF8003 Domain of unknown function (DUF8003) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 1.5 3.7 9.5e+03 53 72 .. 159 178 .. 145 181 .. 0.80 2 ? 5.0 6.2 0.018 46 15 67 .. 370 420 .. 361 428 .. 0.60 3 ! 11.1 6.0 0.00022 0.56 5 42 .. 420 461 .. 416 475 .. 0.77 4 ? 3.1 0.2 0.072 1.8e+02 16 26 .. 475 485 .. 460 488 .. 0.77 5 ! 7.6 9.3 0.0027 6.8 4 44 .. 475 519 .. 472 542 .. 0.71 6 ? 1.0 8.1 0.33 8.4e+02 12 39 .. 542 567 .. 520 594 .. 0.58 7 ? 5.1 4.4 0.016 41 15 41 .. 599 625 .. 595 641 .. 0.88 8 ! 10.4 7.5 0.00037 0.95 6 39 .. 641 676 .. 635 703 .. 0.71 9 ! 7.1 3.5 0.0039 9.8 15 44 .. 708 737 .. 695 747 .. 0.89 10 ! 14.5 6.4 1.9e-05 0.048 12 43 .. 760 789 .. 744 807 .. 0.77 11 ! 14.8 2.6 1.6e-05 0.041 15 40 .. 817 842 .. 812 858 .. 0.91 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 3.7 DUF8003 53 gGvaetpCpYkCvsdkykmp 72 ++ ae +C+ kC++ +++++ FUN_000959-T1 159 ESEAERRCEVKCNDSYMELS 178 5668999*****99988765 PP == domain 2 score: 5.0 bits; conditional E-value: 0.018 DUF8003 15 CeeCPvGtYknvtgsdkalCkpCpaee.lpsraeyisvrgGvaetpCpYkCvsd 67 C+ CP+ + n+t++ +C +Cp + ++sra s++++ p +++C+++ FUN_000959-T1 370 CSTCPTNQFYNITAQ---VCEKCPPGTfASSRARSCSQQNSTLLIPLKFSCDNK 420 777777777766655...566665544356666666666666655555555554 PP == domain 3 score: 11.1 bits; conditional E-value: 0.00022 DUF8003 5 kCpkGly....GtfCeeCPvGtYknvtgsdkalCkpCpaeel 42 kC kG + +Ce CP+ tY+n++ + + C+pCp e+ FUN_000959-T1 420 KCMKGKHvdgkSWMCEWCPMDTYQNSSTKVNPDCTPCPGEKK 461 56666542211469************************8764 PP == domain 4 score: 3.1 bits; conditional E-value: 0.072 DUF8003 16 eeCPvGtYknv 26 e+CP GtY n+ FUN_000959-T1 475 EPCPNGTYLNI 485 57******886 PP == domain 5 score: 7.6 bits; conditional E-value: 0.0027 DUF8003 4 kkCpkGlyGtf....CeeCPvGtYknvtgsdkalCkpCpaeelps 44 ++Cp+G y + C +CPvG Y +v+ Ck+C +++ + FUN_000959-T1 475 EPCPNGTYLNIssgtCFKCPVGSYMDVDSHVFLRCKSCGGKKITQ 519 679999886544444***************9*******9854433 PP == domain 6 score: 1.0 bits; conditional E-value: 0.33 DUF8003 12 GtfCeeCPvGtYknvtgsdkalCkpCpa 39 C+ C G+Y+++ + + Ck+C + FUN_000959-T1 542 SKSCSLCREGKYQDEVNQ--DTCKDCDR 567 233666666666644433..44666665 PP == domain 7 score: 5.1 bits; conditional E-value: 0.016 DUF8003 15 CeeCPvGtYknvtgsdkalCkpCpaee 41 C CP tY + +++ Ck C ++ FUN_000959-T1 599 CLDCPFNTYMDNAKHRSKECKACGPNQ 625 99*********************8765 PP == domain 8 score: 10.4 bits; conditional E-value: 0.00037 DUF8003 6 CpkGly....GtfCeeCPvGtYknvtgsdkalCkpCpa 39 C+kG + C+ CP Gt++++ g d+ Ck+C + FUN_000959-T1 641 CRKGTFlnktVSQCQRCPKGTFQDQPGRDT--CKDCDR 676 6666432211456************99966..****98 PP == domain 9 score: 7.1 bits; conditional E-value: 0.0039 DUF8003 15 CeeCPvGtYknvtgsdkalCkpCpaeelps 44 C CP tY ++ +++ Ck C +++ + FUN_000959-T1 708 CLDCPFNTYMDSAKHRSKECKACGPNQITN 737 99*********************9877654 PP == domain 10 score: 14.5 bits; conditional E-value: 1.9e-05 DUF8003 12 GtfCeeCPvGtYknvtgsdkalCkpCpaeelp 43 C+ CP Gt++++ g+dk C++Cp++ FUN_000959-T1 760 VSQCQRCPKGTFQDQPGQDK--CTQCPDTMST 789 456***************87..*****96544 PP == domain 11 score: 14.8 bits; conditional E-value: 1.6e-05 DUF8003 15 CeeCPvGtYknvtgsdkalCkpCpae 40 C++C GtY++++ +++ Ck Cp++ FUN_000959-T1 817 CKPCSYGTYQESENHQSTSCKVCPRQ 842 ************************96 PP >> NCD3G Nine Cysteines Domain of family 3 GPCR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.3 1.3 10 2.5e+04 5 21 .. 165 181 .. 156 185 .. 0.62 2 ! 15.7 0.8 5.6e-06 0.014 21 52 .. 363 393 .. 344 395 .. 0.78 3 ! 6.2 8.8 0.0054 14 6 51 .. 417 459 .. 414 462 .. 0.74 4 ! 10.1 3.5 0.00032 0.82 6 48 .. 473 512 .. 470 518 .. 0.69 5 ? 2.1 1.7 0.1 2.6e+02 28 48 .. 508 532 .. 505 538 .. 0.73 6 ! 9.1 3.8 0.00065 1.7 29 52 .. 545 569 .. 544 571 .. 0.89 7 ! 8.1 4.1 0.0014 3.5 3 52 .. 579 625 .. 577 627 .. 0.81 8 ! 8.9 7.9 0.00074 1.9 9 51 .. 640 677 .. 633 680 .. 0.67 9 ! 7.5 4.2 0.002 5.2 3 52 .. 688 734 .. 686 736 .. 0.79 10 ! 11.5 4.2 0.00011 0.29 9 51 .. 729 769 .. 728 770 .. 0.89 11 ! 10.9 8.8 0.00018 0.45 28 52 .. 762 787 .. 744 789 .. 0.83 12 ! 5.3 8.6 0.0097 25 4 50 .. 798 841 .. 796 844 .. 0.75 Alignments for each domain: == domain 1 score: -4.3 bits; conditional E-value: 10 NCD3G 5 vCsesCppGtrkkvqeg 21 +C +C+ ++ + ++ FUN_000959-T1 165 RCEVKCNDSYMELSMNQ 181 56677766666655555 PP == domain 2 score: 15.7 bits; conditional E-value: 5.6e-06 NCD3G 21 gepvCCfdCipCpegeisntdseeCtkCpedq 52 g++ f C+ Cp +++ n ++ C+kCp ++ FUN_000959-T1 363 GNQ-SFFVCSTCPTNQFYNITAQVCEKCPPGT 393 554.68**********999999*******987 PP == domain 3 score: 6.2 bits; conditional E-value: 0.0054 NCD3G 6 CsesCppGtrkkvqegepvCCfdCipCpegeis.n..tdseeCtkCped 51 C ++C +G+ + +g++ + C+ Cp +++ + + + +Ct+Cp + FUN_000959-T1 417 CDNKCMKGK---HVDGKS---WMCEWCPMDTYQnSstKVNPDCTPCPGE 459 677777774...356777...**********98434345788****966 PP == domain 4 score: 10.1 bits; conditional E-value: 0.00032 NCD3G 6 CsesCppGtrkkvqegepvCCfdCipCpegeisntdsee...CtkC 48 C e+Cp Gt+ ++ +g +C +Cp g++ + ds+ C++C FUN_000959-T1 473 CREPCPNGTYLNISSG------TCFKCPVGSYMDVDSHVflrCKSC 512 8999999999999888......477778888775555442225555 PP == domain 5 score: 2.1 bits; conditional E-value: 0.1 NCD3G 28 dCipCpegeisn.tdsee...CtkC 48 +C++C ++i++ t s++ C +C FUN_000959-T1 508 RCKSCGGKKITQaTGSKTisdCYEC 532 5999*****9966888773335555 PP == domain 6 score: 9.1 bits; conditional E-value: 0.00065 NCD3G 29 CipCpegeis.ntdseeCtkCpedq 52 C+ C eg+++ + ++++C++C++++ FUN_000959-T1 545 CSLCREGKYQdEVNQDTCKDCDRGK 569 **********66*********9875 PP == domain 7 score: 8.1 bits; conditional E-value: 0.0014 NCD3G 3 eSvCsesCppGtrkkvqegepvCCfdCipCpegeis.n..tdseeCtkCpedq 52 +S C C G++ + ++ C +Cp +++ n + s+eC+ C +q FUN_000959-T1 579 SSDCVVVCGLGQYLNDSDE------ACLDCPFNTYMdNakHRSKECKACGPNQ 625 5778888888888877666......5********9766678899*****9887 PP == domain 8 score: 8.9 bits; conditional E-value: 0.00074 NCD3G 9 sCppGtrkkvqegepvCCfdCipCpegeis.ntdseeCtkCped 51 sC++Gt+ +++ + +C++Cp+g+++ + ++C++C+++ FUN_000959-T1 640 SCRKGTFLNKTVS------QCQRCPKGTFQdQPGRDTCKDCDRG 677 4555555555444......5888888888866888888888766 PP == domain 9 score: 7.5 bits; conditional E-value: 0.002 NCD3G 3 eSvCsesCppGtrkkvqegepvCCfdCipCpegeis.n..tdseeCtkCpedq 52 +S C C G++ + ++ C +Cp +++ + + s+eC+ C +q FUN_000959-T1 688 SSDCVVVCGLGQYLNDSDE------ACLDCPFNTYMdSakHRSKECKACGPNQ 734 5778888888888877666......5********854345889******9887 PP == domain 10 score: 11.5 bits; conditional E-value: 0.00011 NCD3G 9 sCppGtrkkvqegepvCCfdCipCpegeisntdseeCtkCped 51 C p+++ +++++ + +C C +g++ n+ ++C++Cp++ FUN_000959-T1 729 ACGPNQITNATGTSN--ISQCFGCRKGTFLNKTVSQCQRCPKG 769 699999999988877..889**********99*********97 PP == domain 11 score: 10.9 bits; conditional E-value: 0.00018 NCD3G 28 dCipCpegeis.ntdseeCtkCpedq 52 +C++Cp+g+++ + +++Ct+Cp+++ FUN_000959-T1 762 QCQRCPKGTFQdQPGQDKCTQCPDTM 787 7**********78**********875 PP == domain 12 score: 5.3 bits; conditional E-value: 0.0097 NCD3G 4 SvCsesCppGtrkkvqegepvCCfdCipCpegeis.n..tdseeCtkCpe 50 S C C + ++ + ++ +C+pC+ g+++ + ++s++C+ Cp+ FUN_000959-T1 798 SACVAICGKEEFYDSSDN------RCKPCSYGTYQeSenHQSTSCKVCPR 841 677777777776666655......6********97533578999****97 PP >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.0 1.2e-07 0.0003 4 76 .. 857 924 .. 854 941 .. 0.93 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 1.2e-07 SEA 4 tgsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspekgsvvvdvvlvfrfp 76 s+++t+l +t++len+s + +++ + +ie++++ +rk ++ ++++ v+ + + gs+++d++l f+ + FUN_000959-T1 857 KMSLRFTSLSWTDELENTSNAFYQKKKMSIEKAIRFELRK---DPSFQSVIVTGMMR--GSIIADFDLFFNEK 924 6799************************************...************99..**********9976 PP >> F5_F8_type_C_2 NedA-like, galactose-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 1.3 2.2e-07 0.00055 11 90 .] 999 1087 .. 989 1087 .. 0.76 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 2.2e-07 F5_F8_type_C_2 11 whta..nedpqwlqvDLgssytissvvltnegdccgerlkgykiqvsddgsnwttvatv.tngpg.......gntetitf.navtaryvrv 90 w+++ + +++lq+D++ + +i+ v + ++ + + +k+yk+++sddg++w ++ + t + ++++ ++ +++t+ry+r+ FUN_000959-T1 999 WQAEytRKMKEYLQIDFKRKVNITGVATQGQS-TSNLFVKQYKLSTSDDGKKWIKYTENgT-SQMlngnqdsTTVVRNNLaTSITTRYIRF 1087 77775556999*********************.589999***********88877766532.11112233446667777888899999985 PP >> TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 4.3 1.5e-05 0.039 13 37 .. 369 394 .. 363 397 .. 0.86 2 ? 4.7 4.5 0.016 40 11 33 .. 431 457 .. 420 462 .. 0.68 3 ? 10.3 2.5 0.00029 0.73 12 36 .. 471 497 .. 465 501 .. 0.74 4 ? 4.6 6.4 0.017 42 6 33 .. 537 566 .. 531 570 .. 0.86 5 ? 7.2 0.8 0.0026 6.7 9 36 .. 577 606 .. 574 611 .. 0.80 6 ? 0.7 4.5 0.29 7.3e+02 8 36 .. 612 645 .. 608 646 .. 0.65 7 ? 10.6 4.7 0.00023 0.59 9 36 .. 633 661 .. 629 665 .. 0.87 8 ? 6.3 7.4 0.0049 13 7 33 .. 646 675 .. 640 680 .. 0.79 9 ? 7.3 0.8 0.0025 6.3 9 36 .. 686 715 .. 683 720 .. 0.80 10 ? 1.2 3.5 0.2 5.2e+02 8 26 .. 721 739 .. 717 754 .. 0.76 11 ? 9.7 4.2 0.00044 1.1 9 36 .. 742 770 .. 739 775 .. 0.87 12 ? 8.7 9.2 0.00091 2.3 7 34 .. 755 785 .. 749 790 .. 0.81 13 ? 2.9 3.3 0.059 1.5e+02 17 36 .. 804 824 .. 794 829 .. 0.56 14 ? 5.6 6.2 0.008 21 6 34 .. 809 841 .. 808 844 .. 0.79 15 ? 5.0 1.5 0.012 32 8 30 .. 830 851 .. 827 852 .. 0.86 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1.5e-05 TNFR_ELAPOR1_6th 13 tCefCpkgsySdG.teeCkkCPagTe 37 +C++Cp++++ + + C+kCP+gT FUN_000959-T1 369 VCSTCPTNQFYNItAQVCEKCPPGTF 394 7*********9984679*******95 PP == domain 2 score: 4.7 bits; conditional E-value: 0.016 TNFR_ELAPOR1_6th 11 sstCefCpkgsySdGte....eCkkCP 33 s Ce Cp ++y + ++ +C+ CP FUN_000959-T1 431 SWMCEWCPMDTYQNSSTkvnpDCTPCP 457 447999999999887542333699998 PP == domain 3 score: 10.3 bits; conditional E-value: 0.00029 TNFR_ELAPOR1_6th 12 stC.efCpkgsy...SdGteeCkkCPagT 36 ++C e+Cp+g+y S+Gt C kCP+g+ FUN_000959-T1 471 TECrEPCPNGTYlniSSGT--CFKCPVGS 497 66757******95556666..*****986 PP == domain 4 score: 4.6 bits; conditional E-value: 0.017 TNFR_ELAPOR1_6th 6 meknnsstCefCpkgsySdG..teeCkkCP 33 +++++s++C+ C +g y d +++Ck C FUN_000959-T1 537 FYNSSSKSCSLCREGKYQDEvnQDTCKDCD 566 6788899**********99876779***95 PP == domain 5 score: 7.2 bits; conditional E-value: 0.0026 TNFR_ELAPOR1_6th 9 nnsstCe.fCpkgsySdG.teeCkkCPagT 36 n ss C +C g+y + +e+C CP +T FUN_000959-T1 577 NTSSDCVvVCGLGQYLNDsDEACLDCPFNT 606 678899636*****96543889******99 PP == domain 6 score: 0.7 bits; conditional E-value: 0.29 TNFR_ELAPOR1_6th 8 knnsstCefCpkgs..ySdGte...eCkkCPagT 36 k++s++C+ C +++ ++ Gt+ +C +C gT FUN_000959-T1 612 KHRSKECKACGPNQitFATGTSnisQCFSCRKGT 645 5678999999999644667754111566665555 PP == domain 7 score: 10.6 bits; conditional E-value: 0.00023 TNFR_ELAPOR1_6th 9 nnsstCefCpkgsySdG.teeCkkCPagT 36 +n s+C C kg++ + ++C++CP gT FUN_000959-T1 633 SNISQCFSCRKGTFLNKtVSQCQRCPKGT 661 5789**********9984469******99 PP == domain 8 score: 6.3 bits; conditional E-value: 0.0049 TNFR_ELAPOR1_6th 7 eknns.stCefCpkgsySd..GteeCkkCP 33 + n++ s+C+ Cpkg++ d G ++Ck C FUN_000959-T1 646 FLNKTvSQCQRCPKGTFQDqpGRDTCKDCD 675 55544279*********9977899*****6 PP == domain 9 score: 7.3 bits; conditional E-value: 0.0025 TNFR_ELAPOR1_6th 9 nnsstCe.fCpkgsySdG.teeCkkCPagT 36 n ss C +C g+y + +e+C CP +T FUN_000959-T1 686 NTSSDCVvVCGLGQYLNDsDEACLDCPFNT 715 678899636*****96543889*****999 PP == domain 10 score: 1.2 bits; conditional E-value: 0.2 TNFR_ELAPOR1_6th 8 knnsstCefCpkgsySdGt 26 k++s++C+ C ++++ + t FUN_000959-T1 721 KHRSKECKACGPNQITNAT 739 567899*******998865 PP == domain 11 score: 9.7 bits; conditional E-value: 0.00044 TNFR_ELAPOR1_6th 9 nnsstCefCpkgsySdG.teeCkkCPagT 36 +n s+C C kg++ + ++C++CP gT FUN_000959-T1 742 SNISQCFGCRKGTFLNKtVSQCQRCPKGT 770 5779**********9984469******99 PP == domain 12 score: 8.7 bits; conditional E-value: 0.00091 TNFR_ELAPOR1_6th 7 eknns.stCefCpkgsySd..GteeCkkCPa 34 + n++ s+C+ Cpkg++ d G+++C++CP FUN_000959-T1 755 FLNKTvSQCQRCPKGTFQDqpGQDKCTQCPD 785 54444289*********997789*******6 PP == domain 13 score: 2.9 bits; conditional E-value: 0.059 TNFR_ELAPOR1_6th 17 CpkgsySdG.teeCkkCPagT 36 C k+ + d +++Ck C gT FUN_000959-T1 804 CGKEEFYDSsDNRCKPCSYGT 824 665555554334666666665 PP == domain 14 score: 5.6 bits; conditional E-value: 0.008 TNFR_ELAPOR1_6th 6 meknnsstCefCpkgsySdG....teeCkkCPa 34 ++ +++ C++C g+y + +++Ck CP FUN_000959-T1 809 FYDSSDNRCKPCSYGTYQESenhqSTSCKVCPR 841 6778899**********7663344469*****6 PP == domain 15 score: 5.0 bits; conditional E-value: 0.012 TNFR_ELAPOR1_6th 8 knnsstCefCpkgsySdGteeCk 30 +++s++C++Cp++ d + +C FUN_000959-T1 830 NHQSTSCKVCPRQGAVDFK-QCA 851 678999*******999999.896 PP >> DUF3792 Protein of unknown function (DUF3792) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.1 0.00011 0.27 55 86 .. 1129 1159 .. 1128 1175 .. 0.77 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00011 DUF3792 55 lagkkagkkgwlhGllvGllyflillllsllv 86 +a+ k+ + gw +G+ +G++++++l+ ++++v FUN_000959-T1 1129 VAAVKTTEDGWPWGAYLGIVFAALLV-IGIVV 1159 6899*******************963.33333 PP >> HU-CCDC81_bac_1 CCDC81-like prokaryotic HU domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 0.017 43 14 36 .. 579 601 .. 578 609 .. 0.86 2 ? 4.8 0.0 0.015 39 14 36 .. 688 710 .. 687 721 .. 0.85 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.017 HU-CCDC81_bac_1 14 ehdcVivPslGgFvaervsAkyd 36 + dcV+v +lG + + +A++d FUN_000959-T1 579 SSDCVVVCGLGQYLNDSDEACLD 601 57*********999999999887 PP == domain 2 score: 4.8 bits; conditional E-value: 0.015 HU-CCDC81_bac_1 14 ehdcVivPslGgFvaervsAkyd 36 + dcV+v +lG + + +A++d FUN_000959-T1 688 SSDCVVVCGLGQYLNDSDEACLD 710 57**********99999999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1210 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1314 (0.0514386); expected 510.9 (0.02) Passed bias filter: 602 (0.0235663); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.52u 0.39s 00:00:00.91 Elapsed: 00:00:00.42 # Mc/sec: 11482.78 // Query: FUN_000960-T1 [L=892] Description: FUN_000960 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-169 564.6 0.0 3.3e-169 564.2 0.0 1.1 1 Aconitase Aconitase family (aconitate hydratase) 3e-39 134.8 0.0 7.6e-39 133.5 0.0 1.7 2 Aconitase_C Aconitase C-terminal domain ------ inclusion threshold ------ 0.25 11.9 0.0 0.52 10.8 0.0 1.5 1 DUF6549 Family of unknown function (DUF6549) Domain annotation for each model (and alignments): >> Aconitase Aconitase family (aconitate hydratase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 564.2 0.0 3.8e-173 3.3e-169 2 462 .] 65 567 .. 63 567 .. 0.94 Alignments for each domain: == domain 1 score: 564.2 bits; conditional E-value: 3.8e-173 Aconitase 2 kiwdahlveeeeg.ellyipdrvllqdvTsvqaledlaaagravrrpgktlatidhlvptdlvidhsv.....e.ee.leknledeiernkeqyef 89 +i+d +++++ ++ e++++p+rv+lqd+T+v+a++d+aa+++av+r+g+++++i++l+p+dlvidhsv + ++ l+kn + e+ rnke++ f FUN_000960-T1 65 NILDWENNQK-QNvEIPFLPSRVILQDFTGVPAVVDFAAMRDAVKRLGGEPDKINPLCPVDLVIDHSVqvdvsRsSTaLQKNQDIEFMRNKERFLF 159 5644333334.3348********************************************************98446679***************** PP Aconitase 90 Lksnakkf.girlvppgqGIvHqvnlEq.........glalpgmtivgtDSHTtthgglGalafGvGgseaeavlatqtlelkipkvvgvkltGkl 175 Lk+++k+f ++++vppg+GIvHqvnlE+ ++++p+ ++vgtDSHTt+++glG++++GvGg+eaeav+++q +++ +pkvvg+kltG++ FUN_000960-T1 160 LKWGSKAFkNMTIVPPGSGIVHQVNLEYlgrvvfnmnNVLYPD-SVVGTDSHTTMINGLGIVGWGVGGIEAEAVMLGQAISMVLPKVVGYKLTGQV 254 **********************************9988*****.**************************************************** PP Aconitase 176 kegvtakDlilaiigklrkkggtgkvvEffGegvesLsledraTicnmaiEaGAtaglfpvdettleYlkatgreeapk.lgeayekavalwelks 270 k+ +t++D++l+i+++lr+ g++gk+vEffG+gv++Ls++draTi+nm++E+GAt+g+fpvde+ l Yl++tgr++++ +e+y ka+++++ +s FUN_000960-T1 255 KPYITSTDVVLTITKHLRQVGVVGKFVEFFGPGVSHLSIADRATIANMCPEYGATIGFFPVDEKSLMYLRQTGRPDEALeCVETYLKATKMFRDYS 350 ******************************************************************************9899**********7665 PP Aconitase 271 de..daeydkvveldlseiepsvagptsPqdavplseevpepefkeele.............reaaekaleyglekgtkledgkvdiafigSCTNs 351 d+ d+++++vv ldls+++ s++gp++P+d+v+ls++++ +f ++l+ ++++e +++ ++k++kl++g+v+ia+i+SCTN+ FUN_000960-T1 351 DPdnDPVFSEVVVLDLSTVTSSLSGPKRPHDRVSLSSMKQ--DFIDCLNnrvgfkgfgipveKQSIEVPFTF-DGKEYKLSHGSVVIAAITSCTNT 443 5533899****************************77776..78888888999*****99888888888888.5779******************* PP Aconitase 352 siedlraaagllk.kavekglkvapgvkalvvPGSeqvkeqleaeGldkileeaGfevreagCstCignsdrle........ege...asvsssNR 435 s+++++ ag+++ kave gl+v+p++k++++PGS++v+ +l+++G+ + le++Gf+++++gC+tCigns++l+ +g+ a ++s+NR FUN_000960-T1 444 SNPSVMLGAGMVAkKAVELGLEVKPYIKTSLSPGSGVVTYYLRESGVIPSLEKLGFHIVGYGCMTCIGNSGPLSepvaeaieKGDlvaAGILSGNR 539 *************9***********************************************************98998888766699999****** PP Aconitase 436 NFegRqgpgtrt.yLaSPalvaaaAiaG 462 NFegR++p tr+ yLaSP+lv+a+AiaG FUN_000960-T1 540 NFEGRIHPLTRAnYLASPPLVVAYAIAG 567 ***************************9 PP >> Aconitase_C Aconitase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.7 1.5e+04 14 42 .. 597 625 .. 595 633 .. 0.76 2 ! 133.5 0.0 8.9e-43 7.6e-39 2 128 .. 696 821 .. 695 824 .. 0.97 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.7 Aconitase_C 14 deksnvdtdlkipkqlektianigignel 42 +e + v+++ ip ++++ a++ gn FUN_000960-T1 597 EELQVVERQYVIPAMFKEVYAKVTTGNPR 625 56678899999999999999998887755 PP == domain 2 score: 133.5 bits; conditional E-value: 8.9e-43 Aconitase_C 2 evllklkGlstkdeksnvdtdlkipkqlektianigignelfeekranktrdlddkekedvvdaaerykeegaklvviagknfGeGSSRehAAlal 97 +++l ++Gl+ ++++s+++++++ +++ ++t+ani++ n+++ k a kt + ++++++d++da ery+ee+++l+++agk++G+GSSR++AA+++ FUN_000960-T1 696 ARYLAANGLAPREFNSYGSRRGNDAVMTRGTFANIRLVNKFIG-KAAPKTVHFPSGDTMDIFDASERYREEKRQLIILAGKDYGSGSSRDWAAKGP 790 68999**********************************9987.889999999******************************************* PP Aconitase_C 98 rdlGikaviaeSFarIfenNliknglLplel 128 lG+kavi+eSF+rI+++Nl+++g++ple+ FUN_000960-T1 791 WMLGVKAVITESFERIHRSNLVGMGIIPLEY 821 *****************************98 PP >> DUF6549 Family of unknown function (DUF6549) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 6.1e-05 0.52 57 146 .. 56 169 .. 42 186 .. 0.68 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 6.1e-05 DUF6549 57 lgikikrveaaakveletkveikaplrdsivv................lDtvksf....ewrdpwlqvegiiekdslkvrvesvdtLrQ....vvh 128 +++k+k+ve++ e + k +++ p s v+ +D+vk++ +p v+ +i + s++v v+ + t Q + + FUN_000960-T1 56 FQVKSKDVENILDWENNQKQNVEIPFLPSRVIlqdftgvpavvdfaamRDAVKRLggepDKINPLCPVDLVI-DHSVQVDVSRSSTALQknqdIEF 150 677777777777777777777777766665555777777777777777777777722222345566666555.56779999888887664444556 PP DUF6549 129 r.vkrrflfirwgtkalrQ 146 k+rflf++wg ka++ FUN_000960-T1 151 MrNKERFLFLKWGSKAFKN 169 669*************985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (892 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 446 (0.0174594); expected 510.9 (0.02) Passed bias filter: 437 (0.0171071); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 8583.56 // Query: FUN_000961-T1 [L=964] Description: FUN_000961 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-109 365.0 5.6 6.4e-99 331.1 0.2 3.5 5 Beta-prop_EML_2 Echinoderm microtubule-associated 1.6e-98 329.9 4.1 6.2e-88 295.2 0.2 3.8 4 Beta-prop_EML Echinoderm microtubule-associated 1.2e-42 146.3 6.9 2.6e-22 79.6 0.4 4.8 4 Beta-prop_THOC3 THOC3 beta-propeller domain 1.8e-41 142.6 3.8 7.5e-25 88.0 0.2 4.4 4 WD40_Prp19 Prp19 WD40 domain 6.3e-40 137.3 6.9 9.4e-13 48.7 0.0 5.4 5 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 2.6e-32 112.8 13.9 2.1e-10 40.8 0.1 5.2 5 Beta-prop_WDR5 WDR5 beta-propeller domain 1.5e-31 110.3 8.8 2.6e-08 34.0 0.3 5.7 5 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 7.5e-30 102.6 27.6 9.2e-05 23.3 0.1 11.4 10 WD40 WD domain, G-beta repeat 1.4e-28 100.4 1.4 1.3e-12 48.0 0.0 4.3 4 WD40_WDHD1_1st WDHD1 first WD40 domain 2.3e-22 79.9 0.7 6.1e-08 32.5 0.0 5.3 4 WDR55 WDR55 3.3e-22 78.2 0.0 7e-22 77.1 0.0 1.6 1 HELP HELP motif 1.4e-19 71.0 1.1 1.9e-11 44.4 0.0 5.2 6 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 1.6e-18 67.6 5.8 3.8e-16 59.8 1.0 3.6 4 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 1.3e-17 64.3 3.6 1.3e-05 24.8 0.0 5.2 4 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 2.4e-16 60.1 4.3 0.001 18.6 0.0 5.3 5 WD40_Gbeta G protein beta WD-40 repeat protei 4e-15 56.3 0.2 1.2e-05 25.1 0.0 4.3 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 1.4e-14 54.3 6.6 0.0001 22.0 0.9 4.8 4 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 3.3e-14 53.3 5.0 6.4e-05 22.8 0.0 6.5 8 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 4.2e-14 53.1 2.6 1.8e-08 34.5 0.0 4.5 5 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 2.8e-12 47.3 0.3 7.1e-06 26.8 0.1 2.5 2 EF-hand_7 EF-hand domain pair 4.7e-12 46.0 9.5 0.039 13.4 0.2 6.4 5 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 6.1e-11 42.5 1.5 0.95 9.0 0.0 6.3 7 EIF3I EIF3I 1.2e-10 41.7 0.2 0.00072 19.5 0.0 3.6 4 Beta-prop_RIG_2nd RIG second beta-propeller 5.9e-10 39.7 2.9 0.079 13.7 0.0 6.0 6 ANAPC4_WD40 Anaphase-promoting complex subunit 8.1e-10 38.1 0.2 0.0014 18.7 0.0 3.8 3 EF-hand_6 EF-hand domain 2e-09 37.2 2.9 0.00015 21.1 0.2 4.6 4 Beta-prop_IFT140_1st IFT140 first beta-propeller 1.6e-08 34.0 0.1 0.006 16.5 0.0 3.6 3 EF-hand_1 EF hand domain 5.2e-08 32.5 0.2 0.0011 18.8 0.0 3.4 3 EF-hand_5 EF hand 5.3e-08 33.0 4.2 0.075 12.8 0.0 5.4 5 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 2.9e-07 31.0 0.0 7.1e-07 29.7 0.0 1.6 1 DUF5580_M Family of unknown function (DUF558 4e-07 30.6 0.0 0.0006 20.3 0.0 3.2 3 RMC1_N Regulator of MON1-CCZ1 complex, N- 2.3e-06 27.7 0.4 9e-05 22.5 0.0 2.9 3 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 2.9e-06 27.1 1.3 0.0065 16.1 0.0 3.5 3 Beta-prop_Aladin Aladin seven-bladed propeller 9.3e-06 25.6 1.1 0.033 13.9 0.0 2.9 2 Beta-prop_HPS5 HPS5 beta-propeller 2.9e-05 23.8 2.4 0.4 10.1 0.1 4.1 4 Beta-prop_WDR19_1st WDR19 first beta-propeller 4.9e-05 23.8 0.0 0.019 15.5 0.0 2.4 2 DUF5580 Family of unknown function (DUF558 0.0001 22.4 1.6 0.44 10.4 0.1 3.8 3 Beta-prop_EIPR1 EIPR1 beta-propeller 0.00018 21.0 7.5 0.04 13.3 0.1 4.5 5 NBCH_WD40 Neurobeachin beta propeller domain 0.00032 20.9 0.0 0.54 10.5 0.0 2.5 2 EF-hand_8 EF-hand domain pair 0.0013 18.2 1.6 0.027 13.9 0.0 3.4 5 Beta-prop_IFT122_1st IFT122 first beta-propeller 0.0028 17.3 0.1 0.093 12.3 0.0 2.5 2 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 0.0095 15.2 0.0 0.024 13.8 0.0 1.7 2 Tricorn_2nd Tricorn protease second beta prope ------ inclusion threshold ------ 0.014 15.2 0.0 0.2 11.4 0.0 2.4 2 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller 0.016 14.7 3.1 4 6.7 0.0 4.1 4 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 0.017 14.6 0.0 0.074 12.5 0.0 2.0 2 Ge1_WD40 WD40 region of Ge1, enhancer of mR 0.019 14.6 0.7 6.6 6.2 0.0 3.8 4 WDR90_beta-prop_4th WDR90, 4th beta-propeller 0.028 15.3 0.1 9.6 7.1 0.0 2.9 3 EF-hand_FSTL1 Follistatin-related protein 1, EF- 0.031 14.0 0.4 16 5.2 0.0 3.1 3 Beta-prop_Vps41 Vps42 beta-propeller 0.2 11.9 0.3 0.45 10.7 0.0 1.7 1 SPEF2_C SPEF2 C-terminal domain Domain annotation for each model (and alignments): >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.7 1.5e-09 8e-07 21 168 .. 385 545 .. 383 560 .. 0.83 2 ! 19.0 0.2 2e-06 0.001 20 127 .. 481 595 .. 478 598 .. 0.74 3 ? 5.0 0.0 0.036 19 206 264 .. 562 619 .. 544 621 .. 0.84 4 ? 0.4 0.0 0.89 4.6e+02 2 67 .. 596 665 .. 595 680 .. 0.76 5 ! 331.1 0.2 1.2e-101 6.4e-99 1 266 [] 690 960 .. 690 960 .. 0.96 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 1.5e-09 Beta-prop_EML_2 21 tvrlWdlekkklvakvklekearsvafspdgkllavGl.......kdGsvlvldaetleevvev..kdrkeaisdikfsp...dgklLavgshd 102 +v+++d e + + + ++ +++++s++++pdg +a G ++ ++ v+++++l+++ + + ++ai +++fs+ +g++La + FUN_000961-T1 385 VVVIYDEELHHQRHYTQHTDDIKSLCVHPDGVRIASGQvkghgddAKPHIRVWNSNSLDTICVIgvDYFEDAIFALAFSNkksQGSYLASVEDN 478 68999*999****************************977777777889**********98765115579*********8444589**966544 PP Beta-prop_EML_2 103 nk..iylYdvskkykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkqvtsasalkdv 168 ++ i l+d++ + kk+++ +g+ + ++ + +s ++ +++g+ +++fw++++ k +s+ +l + FUN_000961-T1 479 EYhtITLWDWT-RKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSRGRLSKN 545 33448899986.5788999***********************************99988877666554 PP == domain 2 score: 19.0 bits; conditional E-value: 2e-06 Beta-prop_EML_2 20 ktvrlWdlekkklvakvkle.kearsvafspdgkllavGlkdGsvlvldaet..leevv...evkdrkeaisdikfspdgklLavgshdnkiyl 107 +t++lWd +kk +a+++ + +++ +v+fsp +++ v++ + +v+ ++ ++ l++ + ++r + +s+i+fs + ++L g d++i + FUN_000961-T1 481 HTITLWDWTRKKKLASARGNmDQVLAVNFSPFESHHFVTCGKQHVTFWELDDnkLKQSRgrlSKNHRPKYVSCIAFSVNCDVLT-GDTDGSICV 573 6899***998777777654427899******99999999999999887655511554433335788999************998.99*****99 PP Beta-prop_EML_2 108 Ydvskk..ykkvgklkghssfi 127 + +++ +++g+ + hs+ + FUN_000961-T1 574 WPEESNqiSEELGVRNAHSDSV 595 9755432255666666666666 PP == domain 3 score: 5.0 bits; conditional E-value: 0.036 Beta-prop_EML_2 206 latgddfGkvklfkyPctkkkakykkykgHsshVtnvrFladdsylistGGaDasvfqW 264 ++tgd+ G + ++ + + ++ + ++Hs V ++ l++d ++s GG ++ v W FUN_000961-T1 562 VLTGDTDGSICVWPEESNQISEELGVRNAHSDSVYALLVLPND-VVLSGGGGESIVRAW 619 6799999999999999999999999999999999999999987.788999999888877 PP == domain 4 score: 0.4 bits; conditional E-value: 0.89 Beta-prop_EML_2 2 wGLathpsepqfvTagdDktvrlWdlekkklvakvkleke.....arsvafspdgkllavGlkdGsvlvld 67 ++L + p++ + +g +++vr W + k + +v+l+ + +rs+a+ g++l +G+ d ++ v + FUN_000961-T1 596 YALLVLPNDVVLSGGGGESIVRAWYKRPKLIPTNVELKLPrevsgVRSLALG-TGNQLYIGTVDNHIWVAS 665 788888888888899999999***9777777677777653222226777776.89999*****99999865 PP == domain 5 score: 331.1 bits; conditional E-value: 1.2e-101 Beta-prop_EML_2 1 lwGLathpsepqfvTagdDktvrlWdlekkklvakv.klekearsvafspdgkllavGlkdGsvlvldaetleevvevkd.rkeaisdikfspd 92 l GLa+hps+p+fvT+g Dk+vrlW+++++++v++ kl++e++++af+p +l+avG+k+ + +l+a+t+e ++++++ e+is+i+fspd FUN_000961-T1 690 LRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNnKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIKLTSePPEKISEIQFSPD 783 68********************************8659************************************9997662689********** PP Beta-prop_EML_2 93 gklLavgshdnkiylYdvsk...kykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkqvtsasalkdveWatwtcvlgwevqG 183 g+++a+g+hdn +y+Y++ + +++ ++k h+s + hlDws+d++ lqs+s+dyellfwda +g+q+t++++l+++eW+t++cvlg++v G FUN_000961-T1 784 GTHVALGCHDNDVYIYELLSegrSVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQITASASLRNTEWDTHNCVLGYPVIG 877 *****************9863335778889**************************************************************** PP Beta-prop_EML_2 184 iwpklsdgtdinavdrsksekllatgddfGkvklfkyPctkkkakykkykgHsshVtnvrFladdsylistGGaDasvfqWkv 266 iwp+++dgtd+n+vdrs++++llatgddfG+v+l++yPc+++ka+ +kgHs+hV+nvrFl dd++lis+GG+Das +qWk+ FUN_000961-T1 878 IWPDGADGTDVNSVDRSHNKRLLATGDDFGNVNLYRYPCVSEKAEPWIIKGHSAHVMNVRFLSDDTRLISVGGRDASTLQWKI 960 *********************************************************************************96 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 295.2 0.2 1.2e-90 6.2e-88 1 265 [. 395 662 .. 395 664 .. 0.95 2 ? 0.4 0.0 1 5.3e+02 7 27 .. 685 705 .. 684 708 .. 0.93 3 ! 19.7 0.1 1.3e-06 0.00067 83 231 .. 703 852 .. 698 875 .. 0.79 4 ! 13.8 0.0 8.1e-05 0.042 157 226 .. 886 959 .. 876 962 .. 0.82 Alignments for each domain: == domain 1 score: 295.2 bits; conditional E-value: 1.2e-90 Beta-prop_EML 1 tQRhYlgHtddikclavhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFsk.adggklLaavdesnehvlsvWd 95 +QRhY++Htddik+l+vhp+++ +a+Gqv+g+++d akphir+W+s++l t+ v+g + fe ++ +laFs+ +++g++La+v++++ h++++Wd FUN_000961-T1 395 HQRHYTQHTDDIKSLCVHPDGVRIASGQVKGHGDD---AKPHIRVWNSNSLDTICVIGVDYFEDAIFALAFSNkKSQGSYLASVEDNEYHTITLWD 487 5******************************9876...56********************************72568******************* PP Beta-prop_EML 96 wqkgeklaetktskdkvlavefhpldknllvtcGkkhiaFWtlegkklekkkgifeksekpkyvlclafsengdvitGdsnGnilvWskgtnkisk 191 w++++kla+++++ d+vlav+f+p +++ +vtcGk+h++FW+l+++kl++++g + k+++pkyv c+afs n dv+tGd++G+i+vW +++n+is+ FUN_000961-T1 488 WTRKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSRGRLSKNHRPKYVSCIAFSVNCDVLTGDTDGSICVWPEESNQISE 583 **********************************************************************************************99 PP Beta-prop_EML 192 a..vkkahegsvfsllvlkdgtllsgggkdgkivawdan..lekl.ketelpesaggvraivegkgdqllvgTtknsil 265 + v++ah+ sv++llvl++ ++lsggg + + aw ++ l ++ e++lp+++ gvr+++ g g+ql++gT n+i+ FUN_000961-T1 584 ElgVRNAHSDSVYALLVLPNDVVLSGGGGESIVRAWYKRpkLIPTnVELKLPREVSGVRSLALGTGNQLYIGTVDNHIW 662 74479*******************************9852244442689****************************97 PP == domain 2 score: 0.4 bits; conditional E-value: 1 Beta-prop_EML 7 gHtddikclavhpnkllvatG 27 gH +d + la hp+ + +tG FUN_000961-T1 685 GHCQDLRGLAAHPSSPTFVTG 705 8******************99 PP == domain 3 score: 19.7 bits; conditional E-value: 1.3e-06 Beta-prop_EML 83 vdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhiaFWtlegkklekkkgifeksekpkyvlclafsengd.vitGdsnG 177 v +++v+ +W+ +++ + + ++ ++ a++fhp+ ++lv +G k+ + l+ ++ e i +se p+ + ++fs++g v G + FUN_000961-T1 703 VTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPY--SSLVAVGFKKRGWALLNASTGEL--IIKLTSEPPEKISEIQFSPDGThVALGCHDN 794 6677899******************************8..68999999997755554443333..333456899************96778999** PP Beta-prop_EML 178 nilvWs..kgtnkiskavk.kahegsvfsllvlkdgtllsgggkdgkivawda.nlek 231 ++++++ +++++s +v+ kah++sv+ l +kdg l + d ++ wda + e+ FUN_000961-T1 795 DVYIYEllSEGRSVSLKVRcKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDAlQGEQ 852 *****9543445555555559*******************99*********9733344 PP == domain 4 score: 13.8 bits; conditional E-value: 8.1e-05 Beta-prop_EML 157 kyvlclafsengd.vitGdsnGnilvWsk..gtnkiskavkkahegsvfsllvlkd.gtllsgggkdgkivawd 226 + v +++ s+n + tGd Gn+ +++ ++k + + k h+ v+ + +l+d l+s gg+d + +w+ FUN_000961-T1 886 TDVNSVDRSHNKRlLATGDDFGNVNLYRYpcVSEKAEPWIIKGHSAHVMNVRFLSDdTRLISVGGRDASTLQWK 959 5678888888888456*******999985225889999999**********99987367999*******99996 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 0.8 1e-11 5.4e-09 33 180 .. 390 557 .. 382 558 .. 0.64 2 ! 17.8 0.0 3.6e-06 0.0019 3 84 .. 549 629 .. 546 661 .. 0.82 3 ! 79.6 0.4 4.9e-25 2.6e-22 14 208 .. 649 855 .. 638 866 .. 0.83 4 ! 14.2 0.0 4.4e-05 0.023 131 198 .. 887 958 .. 881 963 .. 0.83 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 1e-11 Beta-prop_THOC3 33 ksklsketelkghtdsVeqlawspthpdllatas.....sDk..tvrlWdvrtgkstatvkt...kgeninlawsp...dGktiavgskd..dt 111 +++l+++ +++ htd++++l+++p+ ++a++ +D +r+W+ ++ ++ + ++ + la+s+ +G+++a+ +++ +t FUN_000961-T1 390 DEELHHQRHYTQHTDDIKSLCVHPDG-VRIASGQvkghgDDAkpHIRVWNSNSLDTICVIGVdyfEDAIFALAFSNkksQGSYLASVEDNeyHT 482 34455566789999999999999986.5778765333322333369999999866555544322344555799986555799999986542269 PP Beta-prop_THOC3 112 vslidvrtgkv.kkeekfkkevnevafspdgkllllttgdgtvevlsypsleevk.....tlkahtsnclcvafd 180 ++l+d +++k + + + ++v v fsp +++ ++t+g+++v ++++ + + + + + ++ + c+af+ FUN_000961-T1 483 ITLWDWTRKKKlASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQsrgrlSKNHRPKYVSCIAFS 557 999997665551566777899999999999999999999999999998654433311321233334556677775 PP == domain 2 score: 17.8 bits; conditional E-value: 3.6e-06 Beta-prop_THOC3 3 kkvhsvawsadGkrLasgsaDktvrvwnleksklsketel.kghtdsVeqlawspthpdllatassDktvrlWdvrtgkstat 84 k v+++a+s++ L +g +D +++vw e+++ s+e + + h+dsV +l + p++ +l ++ ++ vr W r + ++ FUN_000961-T1 549 KYVSCIAFSVNCDVL-TGDTDGSICVWPEESNQISEELGVrNAHSDSVYALLVLPND-VVLSGGGGESIVRAWYKRPKLIPTN 629 6799*******9988.799**************9999876258************75.56666778*******9887655555 PP == domain 3 score: 79.6 bits; conditional E-value: 4.9e-25 Beta-prop_THOC3 14 GkrLasgsaDktvrvwnleks......klsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgenin.lawspdG 100 G++L g +D+ + v +l+ + + ++ ++gh ++ + la +p++p +++t++sDk vrlW + +++ + t + g+ i+ a++p FUN_000961-T1 649 GNQLYIGTVDNHIWVASLNVDltsplkGAVAKSVIQGHCQDLRGLAAHPSSP-TFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQaAAFHPYS 741 67777777777777776664322222233345689***************98.69*********************9998888776599***** PP Beta-prop_THOC3 101 ktiavgskddtvslidvrtgkv..kkeekfkkevnevafspdgkllllttgdgtvevlsy....psleevktlkahtsnclcvafdpkgrylAv 188 + +avg k++ l++++tg+ k +++ ++++e++fspdg++++l+++d++v ++++ s+ ++kahts++ ++++++g+ l + FUN_000961-T1 742 SLVAVGFKKRGWALLNASTGELiiKLTSEPPEKISEIQFSPDGTHVALGCHDNDVYIYELlsegRSVSLKVRCKAHTSSVSHLDWSKDGENLQS 835 ********************962244566689**************************98543345566679********************** PP Beta-prop_THOC3 189 GsaDalvslWDleeliclrt 208 s D WD+ ++ ++ FUN_000961-T1 836 TSTDYELLFWDALQGEQITA 855 ***********988776655 PP == domain 4 score: 14.2 bits; conditional E-value: 4.4e-05 Beta-prop_THOC3 131 evnevafspdgkllllttgdgtvevlsypsleev...ktlkahtsnclcvaf.dpkgrylAvGsaDalvslW 198 +vn+v s++++ll+++ g+v++++yp + e + +k+h+++++ v f + + r++ vG+ Da W FUN_000961-T1 887 DVNSVDRSHNKRLLATGDDFGNVNLYRYPCVSEKaepWIIKGHSAHVMNVRFlSDDTRLISVGGRDASTLQW 958 7999999*********************96544311278************967788999******987666 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.7 1.4e-08 7.3e-06 130 242 .. 398 525 .. 381 538 .. 0.72 2 ! 16.7 0.0 7.7e-06 0.004 8 115 .. 550 662 .. 543 665 .. 0.78 3 ! 88.0 0.2 1.4e-27 7.5e-25 8 206 .. 640 847 .. 636 873 .. 0.84 4 ! 8.1 0.0 0.0032 1.7 8 76 .. 887 958 .. 881 961 .. 0.66 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 1.4e-08 WD40_Prp19 130 kdeeskeaitsaqfHPDGlllgtGtkdg.......tvkiWDiksqk..nvasleghsgavtslaFSeN...GYyLAsasedg..tvklWDLRklkn 211 + ++++++i+s+ +HPDG+ ++ G+ +g +++W+ +s + +v ++ ++a+ +laFS++ G yLAs +++ t+ lWD ++k+ FUN_000961-T1 398 HYTQHTDDIKSLCVHPDGVRIASGQVKGhgddakpHIRVWNSNSLDtiCVIGVDYFEDAIFALAFSNKksqGSYLASVEDNEyhTITLWDWTRKKK 493 345567889**********99999876533333336*******97722555668999*********97788*******9774449*****988887 PP WD40_Prp19 212 fktleldeeskvnsvaFDk..sgqyLavagsdv 242 +++ + + +v +v+F + s ++ +++++v FUN_000961-T1 494 LASARGNM-DQVLAVNFSPfeSHHFVTCGKQHV 525 88766554.478888887521344444455555 PP == domain 2 score: 16.7 bits; conditional E-value: 7.7e-06 WD40_Prp19 8 gilaldlnpsdknlvltGGaDknvvlfdresekvlatlk...ghtkkvtavafhpsedvlvsasaDktvrvwkkeek....etaatlkkhkaevts 96 +++++++ + vltG D++++++ +es+++ ++l +h+ v a+++ p++ vl ++ ++ vr w k k ++ l + v+s FUN_000961-T1 550 YVSCIAFSV--NCDVLTGDTDGSICVWPEESNQISEELGvrnAHSDSVYALLVLPNDVVLSGGGGESIVRAWYKRPKliptNVELKLPREVSGVRS 643 577888774..578**********************996555999*********99888888999*******987764542333445566678888 PP WD40_Prp19 97 lsvhptgdylvsaskDgtw 115 l++ +++++ + ++ w FUN_000961-T1 644 LALGTGNQLYIGTVDNHIW 662 8888888877777777666 PP == domain 3 score: 88.0 bits; conditional E-value: 1.4e-27 WD40_Prp19 8 gilaldlnpsdknlvltGGaDknvvlfdr........esekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevt 95 g+++l+l + n++ G +D+++ + + + + ++gh + +a hps+ ++v++++Dk vr+w++++++++ t +k +e++ FUN_000961-T1 640 GVRSLALG--TGNQLYIGTVDNHIWVASLnvdltsplKGAVAKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQ 733 66666665..3566777777777777555223333323444556789************************************************* PP WD40_Prp19 96 slsvhptgdylvsaskDgtwalhdletgktllkvkdeeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasl....eghsgavtslaFSe 187 + ++hp +++++ + k + wal +++tg+ + k+++e e+i+ +qf PDG+ +++G++d+ v i+++ s+ sl ++h+++v+ l+ S FUN_000961-T1 734 AAAFHPYSSLVAVGFKKRGWALLNASTGELIIKLTSEPP-EKISEIQFSPDGTHVALGCHDNDVYIYELLSEGRSVSLkvrcKAHTSSVSHLDWSK 828 **********************************99885.79***************************999999998666679************ PP WD40_Prp19 188 NGYyLAsasedgtvklWDL 206 +G +L s+s+d + +WD FUN_000961-T1 829 DGENLQSTSTDYELLFWDA 847 *****************94 PP == domain 4 score: 8.1 bits; conditional E-value: 0.0032 WD40_Prp19 8 gilaldlnpsdknlvltGGaDknvvlfdr...esekvlatlkghtkkvtavafhpsedvlvs.asaDktvrvw 76 +++++d ++ +k+l++tG +nv l+ +++ +kgh+ +v +v+f ++++ l+s ++ D + w FUN_000961-T1 887 DVNSVDRSH-NKRLLATGDDFGNVNLYRYpcvSEKAEPWIIKGHSAHVMNVRFLSDDTRLISvGGRDASTLQW 958 566777664.467778888888999987522234444456789999999999987776665547777776666 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.2 1.4 5.4e-11 2.8e-08 13 146 .. 388 534 .. 382 539 .. 0.78 2 ! 12.7 0.0 0.0002 0.11 27 98 .. 546 619 .. 533 622 .. 0.70 3 ! 18.4 0.0 3.7e-06 0.0019 105 174 .. 679 748 .. 628 755 .. 0.70 4 ! 48.7 0.0 1.8e-15 9.4e-13 15 106 .. 757 853 .. 752 860 .. 0.87 5 ! 21.4 0.0 4.5e-07 0.00023 30 101 .. 886 961 .. 864 963 .. 0.89 Alignments for each domain: == domain 1 score: 34.2 bits; conditional E-value: 5.4e-11 Beta-prop_WDR3_1st 13 vWdlkkgekvatlegeksevtalaaspdgkklavGyadg.......sirlwdlesge..levtfngHksavtalafdk...dgsrLasGsk 91 ++d + ++ + +++++++++l+++pdg ++a+G g +ir+w+ +s + + + + + a+ alaf++ +gs Las FUN_000961-T1 388 IYDEELHH-QRHYTQHTDDIKSLCVHPDGVRIASGQVKGhgddakpHIRVWNSNSLDtiCVIGVDYFEDAIFALAFSNkksQGSYLASVED 477 55544443.34567899*****************9866533333446******997611556677889********862226889***887 PP Beta-prop_WDR3_1st 92 Dt..diivwDvvaeaglfrLkgHkdqvtsvafle.ekkvlvssSkDtliklWdletqh 146 ++ +i +wD +++++l +g dqv +v f++ e+++ v+++k + + +W+l+ ++ FUN_000961-T1 478 NEyhTITLWDWTRKKKLASARGNMDQVLAVNFSPfESHHFVTCGK-QHVTFWELDDNK 534 64448****************************846678999999.6799****9876 PP == domain 2 score: 12.7 bits; conditional E-value: 0.0002 Beta-prop_WDR3_1st 27 geksevtalaaspdgkklavGyadgsirlwdlesgelevtf...ngHksavtalafdkdgsrLasGskDtdiivw 98 + + v+++a+s + + +G +dgsi +w es++++ + n+H+ +v al +++ L G+ ++ + w FUN_000961-T1 546 HRPKYVSCIAFSVNC-DVLTGDTDGSICVWPEESNQISEELgvrNAHSDSVYALLVLPNDVVLSGGGGESIVRAW 619 334678999998855.57789999999999988887765443348999999999888887777777766666555 PP == domain 3 score: 18.4 bits; conditional E-value: 3.7e-06 Beta-prop_WDR3_1st 105 glfrLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtgs 174 ++gH ++ +a +++ + v++++D++++lW ++++ v t + se+ + a+++ ++l+++g FUN_000961-T1 679 AKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGF 748 3445788888888888888888899999999999999888888888888888888888888888777775 PP == domain 4 score: 48.7 bits; conditional E-value: 1.8e-15 Beta-prop_WDR3_1st 15 dlkkgekvatlege.ksevtalaaspdgkklavGyadgsirlwdl....esgelevtfngHksavtalafdkdgsrLasGskDtdiivwDv 100 + +ge + +l++e ++++ +++spdg+++a G +d+ + +++l +s +l+v ++H+s+v+ l+++kdg++L s s+D ++ wD FUN_000961-T1 757 NASTGELIIKLTSEpPEKISEIQFSPDGTHVALGCHDNDVYIYELlsegRSVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDA 847 677899999997652699***************************54444456788899*******************************9 PP Beta-prop_WDR3_1st 101 vaeagl 106 ++++++ FUN_000961-T1 848 LQGEQI 853 998775 PP == domain 5 score: 21.4 bits; conditional E-value: 4.5e-07 Beta-prop_WDR3_1st 30 sevtalaaspdgkklavGyadgsirlwdl...esgelevtfngHksavtalafdkdgsrLas.GskDtdiivwDvv 101 ++v+++ +s++++ la+G + g+++l+ + ++++ ++gH+++v+ ++f +d++rL+s G++D + w +v FUN_000961-T1 886 TDVNSVDRSHNKRLLATGDDFGNVNLYRYpcvSEKAEPWIIKGHSAHVMNVRFLSDDTRLISvGGRDASTLQWKIV 961 689************************986657778889*********************9978999998888876 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 3.2 1.2e-09 6.3e-07 30 186 .. 386 559 .. 381 561 .. 0.79 2 ! 18.6 0.1 2.4e-06 0.0013 70 159 .. 523 619 .. 513 626 .. 0.66 3 ! 19.3 0.0 1.5e-06 0.00078 40 123 .. 679 762 .. 648 771 .. 0.82 4 ! 40.8 0.1 4.1e-13 2.1e-10 7 84 .. 773 854 .. 766 862 .. 0.90 5 ! 13.7 0.0 7.7e-05 0.04 50 119 .. 887 960 .. 882 963 .. 0.85 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 1.2e-09 Beta-prop_WDR5 30 ikiwdveegklektleghkkGisdvawssdskllasa.....SDDk..tvriwdvetgk..llktlkgHtnyvfcvaFn...pkgnllvSGsfDe 112 + i+d ee ++++ + h++ i++++ +d+ +as+ DD +r+w+ ++ ++ + +++ +f++aF+ +g+ l+S +e FUN_000961-T1 386 VVIYD-EELHHQRHYTQHTDDIKSLCVHPDGVRIASGqvkghGDDAkpHIRVWNSNSLDtiCVIGVDYFEDAIFALAFSnkkSQGSYLASVEDNE 479 56666.46789999****************9999997555556997346******9877457778899**********83224678999998876 PP Beta-prop_WDR5 113 ..tvrlWdvrtgkclktlpaHsdpvsavdfnr.dgtlivsssyDgliriwdtetgqclkt...lveddnp.pvsfvkFspn 186 t+ lWd +++k l + + +d+v av+f+ +++ +v++ + w+ + ++ ++ l ++++p vs+++Fs n FUN_000961-T1 480 yhTITLWDWTRKKKLASARGNMDQVLAVNFSPfESHHFVTCGKQ-HVTFWELDDNKLKQSrgrLSKNHRPkYVSCIAFSVN 559 558***************************97256678888765.678898877766554222776655558999999988 PP == domain 2 score: 18.6 bits; conditional E-value: 2.4e-06 Beta-prop_WDR5 70 ktvriwdvetgk....llktlkgHt.nyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktl...paHsdpvsavdfnrdgtlivsssyDgli 156 + v w+++ +k + k H +yv c+aF+ ++++l +G +D ++ +W +++++ + l +aHsd v a+ + ++ + + ++ FUN_000961-T1 523 QHVTFWELDDNKlkqsRGRLSKNHRpKYVSCIAFSVNCDVL-TGDTDGSICVWPEESNQISEELgvrNAHSDSVYALLVLPNDVVLSGGGGESIV 616 45666777644422223344455543688888888888754.78888888888888887777765556888888888887777777777777777 PP Beta-prop_WDR5 157 riw 159 r w FUN_000961-T1 617 RAW 619 777 PP == domain 3 score: 19.3 bits; conditional E-value: 1.5e-06 Beta-prop_WDR5 40 lektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgk 123 +++++gh + + +a + s + +++ Dk vr+w++++++++ t + + + + aF+p ++l++ G l +++tg+ FUN_000961-T1 679 AKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGE 762 5678999************************************9999999************9999988666655555555555 PP == domain 4 score: 40.8 bits; conditional E-value: 4.1e-13 Beta-prop_WDR5 7 kavssvkfspdgkllasasaDktikiwdv....eegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllk 84 +++s ++fspdg+ +a + D+ + i+++ ++++l+ +++h++ +s++ ws+d++ l s S D + wd+ +g++++ FUN_000961-T1 773 EKISEIQFSPDGTHVALGCHDNDVYIYELlsegRSVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQIT 854 679*************************8655556679999**********************************9998765 PP == domain 5 score: 13.7 bits; conditional E-value: 7.7e-05 Beta-prop_WDR5 50 GisdvawssdskllasaSDDktvriwdve...tgkllktlkgHtnyvfcvaFnpkgnllvS.GsfDetvrlWdv 119 +++v s++ +lla++ D +v++++ ++ ++kgH+ +v+ v+F + + l+S G+ D + W++ FUN_000961-T1 887 DVNSVDRSHNKRLLATGDDFGNVNLYRYPcvsEKAEPWIIKGHSAHVMNVRFLSDDTRLISvGGRDASTLQWKI 960 6999**********************9653336778889*************9998888876899999888875 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.4 1.4e-07 7.5e-05 122 240 .. 390 520 .. 364 524 .. 0.72 2 ! 34.0 0.3 5e-11 2.6e-08 31 199 .. 434 612 .. 430 625 .. 0.79 3 ! 29.6 0.1 1.1e-09 5.6e-07 93 194 .. 638 745 .. 628 764 .. 0.82 4 ! 31.9 0.1 2.2e-10 1.2e-07 66 213 .. 744 851 .. 742 869 .. 0.53 5 ! 10.1 0.0 0.00097 0.51 53 197 .. 887 950 .. 877 963 .. 0.41 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 1.4e-07 WD40_CDC20-Fz 122 tkelevvktlkahkqevcglkwspdgrllAsG.....gndn..tvkiwdlrslsp..llkltehkaavkAlaWcpwkks..lLatGGGtaDktirl 206 +el+ ++++++h++++ +l + pdg +AsG g d +++w+++sl+ + ++ + a+ Ala++ k++ +La+ ++ +ti l FUN_000961-T1 390 DEELHHQRHYTQHTDDIKSLCVHPDGVRIASGqvkghGDDAkpHIRVWNSNSLDTicVIGVDYFEDAIFALAFSNKKSQgsYLASVEDNEYHTITL 485 345666788999*******************9444443443336999999999872244567899********988754449************** PP WD40_CDC20-Fz 207 wntntgkllksvdt.gsqvtsllwskeekelvsth 240 w+ + +k+l s qv ++ +s+ e+ +t FUN_000961-T1 486 WDWTRKKKLASARGnMDQVLAVNFSPFESHHFVTC 520 **988777776665157999999999665544444 PP == domain 2 score: 34.0 bits; conditional E-value: 5e-11 WD40_CDC20-Fz 31 vylwnaetgevkelldlseesdyvtsvkwsed...gelLavGtssg..evelwdvekkkklrtleghssrvgalaw....nenllssGsrdgkilh 117 + +wn+++ ++ +++ ++ +d + ++++s++ g++La +++ ++ lwd ++kkkl + +g+ ++v a+++ +++ +++G+++ +++ FUN_000961-T1 434 IRVWNSNSLDTICVIGVDYFEDAIFALAFSNKksqGSYLASVEDNEyhTITLWDWTRKKKLASARGNMDQVLAVNFspfeSHHFVTCGKQHVTFWE 529 779*****99999*****99*********96434489***9877764489************************9977645566899999988888 PP WD40_CDC20-Fz 118 hDvrtkelevvktlkahk.qevcglkwspdgrllAsGgndntvkiwdlrsls...pllkltehkaavkAlaWcpwkkslLatGGGt 199 D ++ + + + k+h+ + v+ +++s + ++l +G d+++++w +s++ +l + h+ v Al p ++++ +GGG FUN_000961-T1 530 LDDNKLKQSRGRLSKNHRpKYVSCIAFSVNCDVL-TGDTDGSICVWPEESNQiseELGVRNAHSDSVYALLVLP--NDVVLSGGGG 612 776555433333445555478999*****99888.7**********887664223677888*********9999..4566677663 PP == domain 3 score: 29.6 bits; conditional E-value: 1.1e-09 WD40_CDC20-Fz 93 ssrvgalaw.nenllssGsrdgkilhhDvrtk......elevvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaavk 181 s v +la ++n l +G+ d++i++ +++ + +++ +++h q+ gl+ p++ ++ +Gg+d++v++w++++ + +++ ++ + ++ FUN_000961-T1 638 VSGVRSLALgTGNQLYIGTVDNHIWVASLNVDltsplkGAVAKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQ 733 56788888867789*********97665555422223324556789************************************************** PP WD40_CDC20-Fz 182 AlaWcpwkkslLa 194 A a++p++ sl+a FUN_000961-T1 734 AAAFHPYS-SLVA 745 ******87.4444 PP == domain 4 score: 31.9 bits; conditional E-value: 2.2e-10 WD40_CDC20-Fz 66 LavGtssgevelwdvekkkklrtlegh.ssrvgalaw..nenllssGsrdgkilhhDvrtk..elevvktlkahkqevcglkwspdgrllAsGgnd 156 +avG ++ l+++++++ + +l+++ ++++ +++ ++++++ G+ d+ ++++++ ++ +++ + ++kah++ v+ l+ws+dg+ l s + d FUN_000961-T1 744 VAVGFKKRGWALLNASTGELIIKLTSEpPEKISEIQFspDGTHVALGCHDNDVYIYELLSEgrSVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTD 839 556666666666666666655555443245566665532334466666666666666544422233344556666666666666666666666666 PP WD40_CDC20-Fz 157 ntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgk 213 + wd+ +g+ FUN_000961-T1 840 YELLFWDAL---------------------------------------------QGE 851 666666653.............................................333 PP == domain 5 score: 10.1 bits; conditional E-value: 0.00097 WD40_CDC20-Fz 53 yvtsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalawnenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgr 148 v sv s++++lLa+G++ g+v+l+ FUN_000961-T1 887 DVNSVDRSHNKRLLATGDDFGNVNLY---------------------------------------------------------------------- 912 34444444444444444444444444...................................................................... PP WD40_CDC20-Fz 149 llAsGgndntvkiwdlrsls...pllkltehkaavkAlaWcpwkkslLatGG 197 +s + + ++ h+a+v + + ++ l+ GG FUN_000961-T1 913 --------------RYPCVSekaEPWIIKGHSAHVMNVRFLSDDTRLISVGG 950 ..............43322211122334444444444444443333333333 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.3 7.6e-05 0.04 5 30 .. 397 427 .. 394 438 .. 0.78 2 ? 4.5 0.0 0.16 82 6 38 .. 496 528 .. 491 529 .. 0.80 3 ! 19.5 0.3 2.9e-06 0.0015 9 38 .. 545 574 .. 538 575 .. 0.87 4 ? 5.4 0.0 0.085 44 4 38 .. 585 619 .. 582 619 .. 0.79 5 ! 23.3 0.1 1.8e-07 9.2e-05 5 38 .. 681 714 .. 678 715 .. 0.92 6 ? 0.9 0.0 2.3 1.2e+03 13 29 .. 731 747 .. 723 751 .. 0.85 7 ! 12.9 0.0 0.00035 0.18 13 38 .. 774 799 .. 761 800 .. 0.85 8 ! 13.3 0.6 0.00026 0.13 6 39 .] 813 846 .. 808 846 .. 0.84 9 ? 5.3 0.1 0.089 46 12 32 .. 886 905 .. 880 907 .. 0.85 10 ! 11.0 0.1 0.0015 0.76 6 38 .. 925 958 .. 922 959 .. 0.78 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 7.6e-05 WD40 5 rtlkgHtsgVtslafspdgsllasg.....s 30 r ++ Ht+++ sl+ +pdg +asg + FUN_000961-T1 397 RHYTQHTDDIKSLCVHPDGVRIASGqvkghG 427 67899*******************9555442 PP == domain 2 score: 4.5 bits; conditional E-value: 0.16 WD40 6 tlkgHtsgVtslafspdgsl.lasgsdDgtvklW 38 + +g + V ++ fsp s+ +++++ +v +W FUN_000961-T1 496 SARGNMDQVLAVNFSPFESHhFVTCG-KQHVTFW 528 55677677************888999.8888888 PP == domain 3 score: 19.5 bits; conditional E-value: 2.9e-06 WD40 9 gH.tsgVtslafspdgsllasgsdDgtvklW 38 H + V+++afs + + l +g+ Dg++++W FUN_000961-T1 545 NHrPKYVSCIAFSVNCDVL-TGDTDGSICVW 574 574455************9.9*99******* PP == domain 4 score: 5.4 bits; conditional E-value: 0.085 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklW 38 l++ ++H+++V++l p++ l g+ + v+ W FUN_000961-T1 585 LGVRNAHSDSVYALLVLPNDVVLSGGGGESIVRAW 619 566789*999***********99555667777766 PP == domain 5 score: 23.3 bits; conditional E-value: 1.8e-07 WD40 5 rtlkgHtsgVtslafspdgsllasgsdDgtvklW 38 +++gH ++ ++la +p+++ +++g+ D+ v+lW FUN_000961-T1 681 SVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLW 714 5689**999****************99******* PP == domain 6 score: 0.9 bits; conditional E-value: 2.3 WD40 13 gVtslafspdgsllasg 29 + + af+p +sl+a+g FUN_000961-T1 731 EIQAAAFHPYSSLVAVG 747 488899********987 PP == domain 7 score: 12.9 bits; conditional E-value: 0.00035 WD40 13 gVtslafspdgsllasgsdDgtvklW 38 ++ + fspdg+++a g++D+ v+++ FUN_000961-T1 774 KISEIQFSPDGTHVALGCHDNDVYIY 799 588999******************98 PP == domain 8 score: 13.3 bits; conditional E-value: 0.00026 WD40 6 tlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +k+Hts+V+ l++s dg l s s D + +Wd FUN_000961-T1 813 RCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWD 846 4789****************84556699999998 PP == domain 9 score: 5.3 bits; conditional E-value: 0.089 WD40 12 sgVtslafspdgsllasgsdD 32 ++V+s++ s++ +lla+g+ D FUN_000961-T1 886 TDVNSVDRSHNKRLLATGD-D 905 35***************98.6 PP == domain 10 score: 11.0 bits; conditional E-value: 0.0015 WD40 6 tlkgHtsgVtslafspdgslla.sgsdDgtvklW 38 ++kgH++ V+ ++f +d++ l+ +g++D + W FUN_000961-T1 925 IIKGHSAHVMNVRFLSDDTRLIsVGGRDASTLQW 958 579**888*****888888877367999887777 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.4 3.3e-07 0.00017 116 259 .. 391 538 .. 383 559 .. 0.81 2 ! 48.0 0.0 2.5e-15 1.3e-12 18 254 .. 560 804 .. 546 811 .. 0.78 3 ! 19.2 0.1 1.5e-06 0.0008 214 259 .. 810 855 .. 803 864 .. 0.88 4 ! 7.7 0.0 0.0046 2.4 88 147 .. 887 949 .. 885 961 .. 0.84 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 3.3e-07 WD40_WDHD1_1st 116 edsskqktleghkapvlsvaldpkgeylaSsscDG.......tvkiWdieskecvktlkvlpksndfsaskslcrlawepksgkllavPvekevk 203 e+ ++q +++h++ ++s++++p g +aS ++ G ++++W+ +s +++ ++ + f+++ ++ + ++g++la ++e + FUN_000961-T1 391 EELHHQRHYTQHTDDIKSLCVHPDGVRIASGQVKGhgddakpHIRVWNSNSLDTI----CVIGVDYFEDAIFALAFSNKKSQGSYLASVEDNEYH 481 566789999**********************999944555555****99877666....44466788888777777777788************* PP WD40_WDHD1_1st 204 lyerdtweeafklsknkls.edisivafSpcGkylaaatvdgeilvWdvatkelier 259 ++ +w+++ kl + + + +++ v fSp ++ ++ ++++ W+++ ++l ++ FUN_000961-T1 482 TITLWDWTRKKKLASARGNmDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQS 538 *************877755478889************************99988764 PP == domain 2 score: 48.0 bits; conditional E-value: 2.5e-15 WD40_WDHD1_1st 18 kkliTcGsDgdvriwegledddpksi....kvgekataiavksdkl.vva.tddntvq.lytfpegekdgi...ltrftapvthialskdgklla 102 ++T+ +Dg +++w + +++ ++++ ++++++a+ v +++ +++ + + +v+ y+ p+ ++++ l r + v+++al +g+ l FUN_000961-T1 560 CDVLTGDTDGSICVWPEESNQISEELgvrnAHSDSVYALLVLPNDVvLSGgGGESIVRaWYKRPKLIPTNVelkLPREVSGVRSLALG-TGNQLY 653 5689***********9999887776511225566789997655555055423345565379******999933344445556677774.99**** PP WD40_WDHD1_1st 103 agseDftikvvsveds........skqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlpksndfsaskslcrlawepk 189 +g+ D +i v s++ + +++gh + + +a +p++ + ++ ++D v++W ++ + v t + + + ++ a++p FUN_000961-T1 654 IGTVDNHIWVASLNVDltsplkgaVAKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNK------L--GSEIQAAAFHPY 740 **********9984333333333336779***********************************9999866443......3..3457789****8 PP WD40_WDHD1_1st 190 sgkllavPvek.evklyerdtweeafklsknklsedisivafSpcGkylaaatvdgeilvWdvatk 254 +l+av ++k l++++t e + kl+++ + +is ++fSp+G+++a ++ d++++++++ ++ FUN_000961-T1 741 -SSLVAVGFKKrGWALLNASTGELIIKLTSEPPE-KISEIQFSPDGTHVALGCHDNDVYIYELLSE 804 .9******7773689**************98886.6*************************98665 PP == domain 3 score: 19.2 bits; conditional E-value: 1.5e-06 WD40_WDHD1_1st 214 fklsknklsedisivafSpcGkylaaatvdgeilvWdvatkelier 259 k++ +++++++s + +S++G+ l ++++d e+l Wd+ + e+i++ FUN_000961-T1 810 LKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQITA 855 567789999****************************999999876 PP == domain 4 score: 7.7 bits; conditional E-value: 0.0046 WD40_WDHD1_1st 88 pvthialskdgkllaagseDftikvvsv...edsskqktleghkapvlsvaldpkgeylaSss 147 +v++++ s++++lla g + +++++ +++ + ++gh+a v+ v++ + + l+S + FUN_000961-T1 887 DVNSVDRSHNKRLLATGDDFGNVNLYRYpcvSEKAEPWIIKGHSAHVMNVRFLSDDTRLISVG 949 78999999999988888877899999865558889999*********************9986 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.1 1.9e-07 9.9e-05 111 247 .. 473 618 .. 389 630 .. 0.76 2 ? 0.4 0.0 0.72 3.7e+02 107 141 .. 699 733 .. 641 747 .. 0.62 3 ! 32.5 0.0 1.2e-10 6.1e-08 8 88 .. 773 853 .. 767 869 .. 0.92 4 ! 16.4 0.0 9.9e-06 0.0052 10 72 .. 888 949 .. 884 959 .. 0.86 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.9e-07 WDR55 111 atGddd..GtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfnirkkklevq....seeyeeellslalvkeekkvvvGsse 200 a+ +d+ t+ lWD +kk++ + + + d + ++ ++ + + ++t+g ++t++++ +kl+ + s+++ + +s+ + + v++G+ + FUN_000961-T1 473 ASVEDNeyHTITLWDWTRKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSrgrlSKNHRPKYVSCIAFSVNCDVLTGDTD 568 554444225899****999****************************************99998643333899999999999************** PP WDR55 201 Gklylfnw..gefgahsdrfpghkesidclvpitenivvtgs.eDGiiRa 247 G++ ++ ++ ++ + h++s+ +l+ + +++v+ g+ + i+Ra FUN_000961-T1 569 GSICVWPEesNQISEELGVRNAHSDSVYALLVLPNDVVLSGGgGESIVRA 618 ******64114444444445689999*99999999999987515666776 PP == domain 2 score: 0.4 bits; conditional E-value: 0.72 WDR55 107 enllatGdddGtvklWDlRkkkavmelkehedyis 141 + +++tG d +v+lW +++ v++ ++ i+ FUN_000961-T1 699 SPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQ 733 44677777777777777666666666665555555 PP == domain 3 score: 32.5 bits; conditional E-value: 1.2e-10 WDR55 8 dlvvdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklk 88 +++ +i+f+P+ +a+g d dv++y+ e ++ + +++++h++s+ ++ +s+dG++l s+s+D + + d+ +g+ + FUN_000961-T1 773 EKISEIQFSPDGTHVALGCHDNDVYIYELLSEGRSVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQI 853 57999**************************99999999********************************9998877655 PP == domain 4 score: 16.4 bits; conditional E-value: 9.9e-06 WDR55 10 vvdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvs 72 v++++ + ++ ++a+g+ G+v ly+y + + e+ e + ++ h+ + +v+F +d ++l+sv FUN_000961-T1 888 VNSVDRSHNKRLLATGDDFGNVNLYRYPCVS-EKAEPWIIKGHSAHVMNVRFLSDDTRLISVG 949 56666677899******************76.57899**********************9984 PP >> HELP HELP motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.1 0.0 1.3e-24 7e-22 1 40 [] 348 387 .. 348 387 .. 0.98 Alignments for each domain: == domain 1 score: 77.1 bits; conditional E-value: 1.3e-24 HELP 1 pPdekLeLewVyGYRgkDcrnNlfllptGeiVYftAAvgv 40 pP+e+L+LewVyGYRg+DcrnNl++l++Gei+Yf+AAv+v FUN_000961-T1 348 PPEERLQLEWVYGYRGRDCRNNLHVLSSGEIIYFIAAVVV 387 69*************************************8 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 4.2 2.2e+03 134 151 .. 82 106 .. 77 117 .. 0.73 2 ? 1.3 0.0 0.51 2.7e+02 8 56 .. 385 432 .. 378 483 .. 0.74 3 ! 7.3 0.0 0.0074 3.9 173 244 .. 482 556 .. 433 565 .. 0.78 4 ! 15.7 0.0 2e-05 0.011 131 263 .. 482 619 .. 475 621 .. 0.81 5 ! 44.4 0.0 3.6e-14 1.9e-11 128 263 .. 707 845 .. 669 846 .. 0.92 6 ? 2.7 0.0 0.19 98 201 263 .. 893 958 .. 882 960 .. 0.78 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 4.2 Beta-prop_WDR36-Utp21_1st 134 lwNirtgkliytfksfk.......s 151 l+N++++kl++ k+f+ + FUN_000961-T1 82 LINVSKQKLLHVQKKFSsldtdnsG 106 89*********99988755555554 PP == domain 2 score: 1.3 bits; conditional E-value: 0.51 Beta-prop_WDR36-Utp21_1st 8 sfqtYdlsklrllfvseqlpekItalaadkdlvfaavgnkivvfkrgke 56 + +Yd ++l+ +q+ ++I++l+++ d v +a+g+ + +k FUN_000961-T1 385 VVVIYD-EELHHQRHYTQHTDDIKSLCVHPDGVRIASGQVKGHGDDAKP 432 567788.788888899999999999999999999999876555555554 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0074 Beta-prop_WDR36-Utp21_1st 173 eivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssGdialwdLekr...rlvhvlrnaHe.ggvtklef 244 +i+l + ++l + + + ++v ++ F ++++++t ++ ++++w+L+++ + + l++ H+ + v+++ f FUN_000961-T1 482 TITLWDWTRKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQ-HVTFWELDDNklkQSRGRLSKNHRpKYVSCIAF 556 688888889999999999999999999999999999998776.999999999834444556677776335666655 PP == domain 4 score: 15.7 bits; conditional E-value: 2e-05 Beta-prop_WDR36-Utp21_1st 131 slqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllkl.....kqeegpvtsisFrtDgepvla 209 ++ lw+ +k + + ++ +++ a++ sp + + + + ++++ +++ ++ + ++ + v++i+F + + + FUN_000961-T1 482 TITLWDWTRKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSRgrlskNHRPKYVSCIAFSVNCD--VL 563 5789*****************************************999986654433322221233557999**999755..78 PP Beta-prop_WDR36-Utp21_1st 210 tgsssGdialwdLekrrlvhvl..rnaHeggvtkleflpgqpllvtsgaDNslkew 263 tg ++G+i++w e++++ + l rnaH+ +v l +lp+ +l g+ ++ w FUN_000961-T1 564 TGDTDGSICVWPEESNQISEELgvRNAHSDSVYALLVLPNDVVLSGGGGESIVRAW 619 9***********9999888874339**************99988777777777766 PP == domain 5 score: 44.4 bits; conditional E-value: 3.6e-14 Beta-prop_WDR36-Utp21_1st 128 kqGslqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqe.egpvtsisFrtDgepvlat 210 ++ ++lw +++++ t ++++s+i+a + p ++va+g+++ l n ++e ++kl++e ++++ i F Dg+ + a FUN_000961-T1 707 SDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIKLTSEpPEKISEIQFSPDGT-HVAL 789 444799********************************************************99789**********97.679* PP Beta-prop_WDR36-Utp21_1st 211 gsssGdialwdLekr...rlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkew 263 g+++ d+++++L ++ ++v +aH+++v++l + ++ + l ++++D l w FUN_000961-T1 790 GCHDNDVYIYELLSEgrsVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFW 845 ***********988655444556679************************888766 PP == domain 6 score: 2.7 bits; conditional E-value: 0.19 Beta-prop_WDR36-Utp21_1st 201 rtDgepvlatgsssGdialwdL..ekrrlvhvlrnaHeggvtkleflpgqpllvtsg.aDNslkew 263 r+ ++ +latg + G++ l+ +++ + + H+++v +++fl++ l++ g +D s +w FUN_000961-T1 893 RSHNKRLLATGDDFGNVNLYRYpcVSEKAEPWIIKGHSAHVMNVRFLSDDTRLISVGgRDASTLQW 958 556678999999999988876511456888888999******************987456665555 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.8 1.0 7.3e-19 3.8e-16 8 185 .. 374 562 .. 371 583 .. 0.80 2 ? 5.2 0.0 0.028 15 86 156 .. 691 759 .. 674 768 .. 0.70 3 ? 2.6 0.0 0.18 96 40 106 .. 774 842 .. 763 858 .. 0.75 4 ? -2.8 0.0 7.9 4.1e+03 76 146 .. 924 951 .. 890 958 .. 0.58 Alignments for each domain: == domain 1 score: 59.8 bits; conditional E-value: 7.3e-19 WD40_MABP1-WDR62_1st 8 ktGlvaypagcvvvllnpkknkqkhilntsrkalsalafspdGkylvtGe.sgh....lpavrvwdva..eksqvaelqkhkygvacva 89 ++G + y vvv+++ + ++q+h + + +l+ pdG + +G+ gh +p +rvw+ + ++ v+ ++ + + +a FUN_000961-T1 374 SSGEIIYFIAAVVVIYDEELHHQRHYTQH-TDDIKSLCVHPDGVRIASGQvKGHgddaKPHIRVWNSNslDTICVIGVDYFEDAIFALA 461 5899*********************7765.5789**************98447755557******987224566777888888899999 PP WD40_MABP1-WDR62_1st 90 fspne...kyivsvgyqhdmvvnvwdwkkdvvvaank.vsskvtavsfse.dssyfvtvGnrhvkfwyldaskekkveatvpllGrsGl 173 fs+++ +y+ sv + ++ +wdw ++ +a+ + +v av fs +s +fvt G++hv fw ld+ k k++ + + r FUN_000961-T1 462 FSNKKsqgSYLASVEDNEYHTITLWDWTRKKKLASARgNMDQVLAVNFSPfESHHFVTCGKQHVTFWELDDNKLKQSRGRLSKNHRPKY 550 997542227******************888777777614579*******736779*****************99998877766666655 PP WD40_MABP1-WDR62_1st 174 lGelrnnlfcdv 185 + + + cdv FUN_000961-T1 551 VSCIAFSVNCDV 562 555555555555 PP == domain 2 score: 5.2 bits; conditional E-value: 0.028 WD40_MABP1-WDR62_1st 86 acvafspnekyivsvgyqhdmvvnvwdwkkdvvv.aankvsskvtavsfsedssyfvtvGnrhvkfwyldas 156 +a p++ v+ g d+vv +w+ ++ vv + nk+ s + a +f s +v+vG ++ + l+as FUN_000961-T1 691 RGLAAHPSSPTFVTGG--SDKVVRLWHADQHRVVwTNNKLGSEIQAAAFHPYS-SLVAVGFKKRGWALLNAS 759 5555555555555444..5899****987766652678***********9875.578999887555556655 PP == domain 3 score: 2.6 bits; conditional E-value: 0.18 WD40_MABP1-WDR62_1st 40 alsalafspdGkylvtGesghlpavrvwdv.aeksqva...elqkhkygvacvafspnekyivsvgyqhdm 106 +s + fspdG+++ G +h v ++++ +e + v+ + h v+ + s++ + + s +++++ FUN_000961-T1 774 KISEIQFSPDGTHVALG--CHDNDVYIYELlSEGRSVSlkvRCKAHTSSVSHLDWSKDGENLQSTSTDYEL 842 68999********9987..89999***99724555554222446677788888888888888887776665 PP == domain 4 score: -2.8 bits; conditional E-value: 7.9 WD40_MABP1-WDR62_1st 76 aelqkhkygvacvafspnekyivsvgyqhdmvvnvwdwkkdvvvaankvsskvtavsfsedssyfvtvGnr 146 +++h v v f +++ ++svg r FUN_000961-T1 924 WIIKGHSAHVMNVRFLSDDTRLISVG-------------------------------------------GR 951 55555555555555555555555555...........................................44 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.1 8.5e-08 4.4e-05 58 198 .. 377 522 .. 361 546 .. 0.69 2 ? 1.2 0.0 0.39 2e+02 22 62 .. 561 601 .. 547 609 .. 0.82 3 ! 24.8 0.0 2.5e-08 1.3e-05 19 152 .. 698 837 .. 690 854 .. 0.68 4 ! 9.7 0.1 0.00098 0.51 91 154 .. 888 952 .. 881 956 .. 0.75 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 8.5e-08 WD40_MABP1-WDR62_2nd 58 kvlyvdeelsalkdvelaasekkdeseldsknGvRvlkvspdgkhlasGDrsG.......niriydletleellki..eahdsevlcle 137 +++y + ++ d+el+++ + +++ + +++l+v+pdg ++asG +G +ir+++ ++l+ ++ i + + +++l FUN_000961-T1 377 EIIYFIAAVVVIYDEELHHQR----HYTQHTDDIKSLCVHPDGVRIASGQVKGhgddakpHIRVWNSNSLDTICVIgvDYFEDAIFALA 461 677777777777777665433....34567788***************8666533333337***********998622668999***** PP WD40_MABP1-WDR62_2nd 138 yskpetglkllasasRD..Rlihvfdvekdysllqtlddhsssitavkfaeeeeklkliscga 198 +s+++++ ++las + i ++d +++ +l+ + + av f+ e + ++++cg FUN_000961-T1 462 FSNKKSQGSYLASVEDNeyHTITLWDWTRKKKLASARG-NMDQVLAVNFSPFE-SHHFVTCGK 522 ************98654124566677777766665433.34456667766543.446666665 PP == domain 2 score: 1.2 bits; conditional E-value: 0.39 WD40_MABP1-WDR62_2nd 22 sFltcssDdtiRlWnleeksseetalkrniysnellkvlyv 62 lt +D +i +W e+++ +e+ rn +s+ + +l + FUN_000961-T1 561 DVLTGDTDGSICVWPEESNQISEELGVRNAHSDSVYALLVL 601 56889999999***999999999999999999998877665 PP == domain 3 score: 24.8 bits; conditional E-value: 2.5e-08 WD40_MABP1-WDR62_2nd 19 pagsFltcssDdtiRlWnleeksseetalkrniysnellkvlyvdeelsal........kdvelaasekkdeseldsknGvRvlkvspd 99 ++ +F+t +sD+ +RlW+++++ + ++n + +e++ + + + ++++ e + + + + + +++spd FUN_000961-T1 698 SSPTFVTGGSDKVVRLWHADQHR---VVWTNNKLGSEIQAAAFHPYSSLVAvgfkkrgwALLNASTGELIIKLTSEPPEKISEIQFSPD 783 4568****************975...344555555555555444333222201100000223333444445567899999********* PP WD40_MABP1-WDR62_2nd 100 gkhlasGDrsGniriydl....etleellkieahdsevlcleyskpetglkllasas 152 g h+a G + iy+l ++++ ++ +ah s v l++sk ++ l s+s FUN_000961-T1 784 GTHVALGCHDNDVYIYELlsegRSVSLKVRCKAHTSSVSHLDWSKDGEN---LQSTS 837 *****************944333456667889***********997655...34444 PP == domain 4 score: 9.7 bits; conditional E-value: 0.00098 WD40_MABP1-WDR62_2nd 91 vRvlkvspdgkhlasGDrsGniriydletleellk...ieahdsevlcleyskpetglkllasasRD 154 v ++ s++ + la+GD Gn+ +y ++e ++ i+ h + v+ + + + + ++l++ ++RD FUN_000961-T1 888 VNSVDRSHNKRLLATGDDFGNVNLYRYPCVSEKAEpwiIKGHSAHVMNVRFLSDD--TRLISVGGRD 952 6677778888999999999999999887766544333399999999999998754..5677777777 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.018 9.1 167 205 .. 387 424 .. 364 470 .. 0.60 2 ! 14.0 0.1 5.1e-05 0.027 78 214 .. 482 622 .. 458 631 .. 0.77 3 ! 18.6 0.0 2e-06 0.001 175 247 .. 678 750 .. 637 770 .. 0.85 4 ! 15.8 0.0 1.4e-05 0.0072 104 179 .. 779 855 .. 772 863 .. 0.88 5 ? 2.7 0.0 0.14 71 180 212 .. 926 959 .. 886 963 .. 0.75 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.018 WD40_Gbeta 167 alwdietgqqttvfvghtgdvmslslapdtrlfvsgacd 205 ++d e +q+ ++ ht d+ sl++ pd+ + sg + FUN_000961-T1 387 VIYDEELHHQR-HYTQHTDDIKSLCVHPDGVRIASGQVK 424 45666655554.688899999999999998888777542 PP == domain 2 score: 14.0 bits; conditional E-value: 5.1e-05 WD40_Gbeta 78 kliiwdsyttnkvhaiplrsswvmtcayap..sgnfvacggldn.icsiynlktregnvrvsrelaghtgylsccrflddnqivtssgdttcalwd 170 + +wd +k+ + v+++ ++p s fv+cg + + + k ++ r+s++ y+sc f + +++t d + ++w FUN_000961-T1 482 TITLWDWTRKKKLASARGNMDQVLAVNFSPfeSHHFVTCGKQHVtFWELDDNKLKQSRGRLSKNH--RPKYVSCIAFSVNCDVLTGDTDGSICVWP 575 456788888888888888888999999998667899***97653134455556666666666643..457************************** PP WD40_Gbeta 171 ietgqqtt...vfvghtgdvmslslapdtrlfvsgacdasaklwdvr 214 e+ q + v h+ v +l + p+ ++ g ++ ++ w r FUN_000961-T1 576 EESNQISEelgVRNAHSDSVYALLVLPNDVVLSGGGGESIVRAWYKR 622 9999976511145789999********99888888888888888766 PP == domain 3 score: 18.6 bits; conditional E-value: 2e-06 WD40_Gbeta 175 qqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsdd 247 ++v+ gh+ d+ l+ p + +fv+g d ++lw + + t s+i+a af p + +a g FUN_000961-T1 678 VAKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGFKK 750 4678899********************************9999999999999**********99999988765 PP == domain 4 score: 15.8 bits; conditional E-value: 1.4e-05 WD40_Gbeta 104 ayapsgnfvacggldnicsiynlktregnvrvsrelaghtgylsccrfldd.nqivtssgdttcalwdietgqqttv 179 ++p g +va g dn + iy+l + v + +ht +s + d +++ ++s d +wd g+q t+ FUN_000961-T1 779 QFSPDGTHVALGCHDNDVYIYELLSEGRSVSLKVRCKAHTSSVSHLDWSKDgENLQSTSTDYELLFWDALQGEQITA 855 689**********************9999*9999**********9999766256777899**********9999886 PP == domain 5 score: 2.7 bits; conditional E-value: 0.14 WD40_Gbeta 180 fvghtgdvmsls.lapdtrlfvsgacdasaklwd 212 + gh+ vm + l+ dtrl+ g das+ w FUN_000961-T1 926 IKGHSAHVMNVRfLSDDTRLISVGGRDASTLQWK 959 5688888888753677777777788888887776 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.1 5e-05 0.026 170 277 .. 493 604 .. 383 615 .. 0.73 2 ! 25.1 0.0 2.4e-08 1.2e-05 4 142 .. 697 833 .. 694 848 .. 0.88 3 ! 11.3 0.0 0.00039 0.2 225 284 .. 888 949 .. 883 955 .. 0.81 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 5e-05 Beta-prop_WDR90_POC16_2nd 170 tldlesskldsAvkvafspaklkhLlvstssnkllkldaktGrllr...evsevhr.sacsslavsedarylltagdkvikvw. 248 +l++++ ++d+ ++v fsp +++h + + ++++ + + +l + ++s+ hr + +s++a s ++ l +d i vw FUN_000961-T1 493 KLASARGNMDQVLAVNFSPFESHHFV-TCGKQHVTFWELDDNKLKQsrgRLSKNHRpKYVSCIAFSVNCDVLTGDTDGSICVWp 575 46778899************998865.555555554444333333211246655542789***********************4 PP Beta-prop_WDR90_POC16_2nd 249 dysmkldinfqvfiGhsekvqqvaftpdq 277 + s +++ + v hs++v ++ p+ FUN_000961-T1 576 EESNQISEELGVRNAHSDSVYALLVLPND 604 45677888999999999999988877754 PP == domain 2 score: 25.1 bits; conditional E-value: 2.4e-08 Beta-prop_WDR90_POC16_2nd 4 ksrrqlatvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqh.rgkvtglvf 86 +s+ ++t +D+ +r+W+ d + ++ + a afhP ++++a Gf++ ++ ++ +l+++ ++ k+ + f FUN_000961-T1 697 PSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIKLTSEpPEKISEIQF 780 55667789999******************99999999*****************999************99875167999**** PP Beta-prop_WDR90_POC16_2nd 87 spdgeylysacslGslalydaseeeyevlrvlgnvvardeelgpealavsedsrrl 142 spdg+++ c + +y+ +e +v +v ++ ++ + + l s+d+++l FUN_000961-T1 781 SPDGTHVALGCHDNDVYIYELLSEGRSV---SLKVRCKAHTSSVSHLDWSKDGENL 833 ********************99988775...4567788888888888888888776 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00039 Beta-prop_WDR90_POC16_2nd 225 csslavsedarylltagd.kvikvwdysmkl.dinfqvfiGhsekvqqvaftpdqqevlsvG 284 + s++ s++ r l+t+ d ++++ y + + + Ghs +v +v f +d ++++svG FUN_000961-T1 888 VNSVDRSHNKRLLATGDDfGNVNLYRYPCVSeKAEPWIIKGHSAHVMNVRFLSDDTRLISVG 949 5678888888888887774468899998654156677888*********************9 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.9 2e-07 0.0001 19 181 .. 432 592 .. 418 599 .. 0.80 2 ! 7.3 0.0 0.0061 3.2 3 120 .. 597 717 .. 595 727 .. 0.72 3 ! 17.8 0.1 4e-06 0.0021 96 171 .. 778 854 .. 766 862 .. 0.80 4 ? 6.4 0.0 0.012 6.2 82 119 .. 922 960 .. 893 963 .. 0.77 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 2e-07 Beta-prop_TEP1_2nd 19 gslqvWkleesssqcllllkahqkavlglalsqk.....llasased..ltvrlWskelltqpekaeslsslsvlrghtgavtccsfsl.d 101 ++vW+ ++ + c++ + + a+++la s+k +las+ ++ t++lW ++l+ rg v fs+ + FUN_000961-T1 432 PHIRVWNSNSLDTICVIGVDYFEDAIFALAFSNKksqgsYLASVEDNeyHTITLWDWTRK---------KKLASARGNMDQVLAVNFSPfE 513 3699***************************98645555899997653379999976443.........345677999999******9835 PP Beta-prop_TEP1_2nd 102 GgllatggrdrsllcWdvrvpkaPvlirsllachr.dWvtgcaWtkddllvscssdGsvglWdiekeqrlgkflGhqsavs 181 +++ t g+ + W++ + k l+ hr +v++ a+ + ++++ +dGs+++W e+++++ + lG ++a s FUN_000961-T1 514 SHHFVTCGKQ-HVTFWELDDNKLKQSRGRLSKNHRpKYVSCIAFSVNCDVLTGDTDGSICVWP-EESNQISEELGVRNAHS 592 6668999986.5778*****999999999*****95689999999999999***********5.66677888888777765 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0061 Beta-prop_TEP1_2nd 3 alvWl.sdkvlvsGaedgslqvWkleess..sqcllllkahqkavlgla..lsqkllasasedltvrlWskelltqpekaeslsslsvlrg 88 al l +d vl G +++ +++W +++ +++ l+l+++ v +la + ++l + ++ + lt p + ++sv++g FUN_000961-T1 597 ALLVLpNDVVLSGGGGESIVRAWYKRPKLipTNVELKLPREVSGVRSLAlgTGNQLYIGTVDNHIWVASLNVDLTSPL--KGAVAKSVIQG 685 55555145566667789999***9998863366777888888888665511677887777665433333334465664..46677899*** PP Beta-prop_TEP1_2nd 89 htgavtccsfsldGgllatggrdrsllcWdvr 120 h + + + ++ tgg d+ + +W FUN_000961-T1 686 HCQDLRGLAAHPSSPTFVTGGSDKVVRLWHAD 717 ****************************9765 PP == domain 3 score: 17.8 bits; conditional E-value: 4e-06 Beta-prop_TEP1_2nd 96 csfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkdd.llvscssdGsvglWdiekeqrlg 171 fs+dG+++a g +d+ ++++++ v ++ h v+ W kd+ l s+s+d + +Wd ++++++ FUN_000961-T1 778 IQFSPDGTHVALGCHDNDVYIYELLSEGRSVSLKVRCKAHTSSVSHLDWSKDGeNLQSTSTDYELLFWDALQGEQIT 854 67999999999999999999999888777777777778899999999999885267889999999999999888876 PP == domain 4 score: 6.4 bits; conditional E-value: 0.012 Beta-prop_TEP1_2nd 82 slsvlrghtgavtccsf.sldGgllatggrdrsllcWdv 119 + +++gh + v f s d +l++ ggrd s l W + FUN_000961-T1 922 EPWIIKGHSAHVMNVRFlSDDTRLISVGGRDASTLQWKI 960 456899*******99993455566789**********86 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 1.2 6.3e+02 75 98 .. 398 421 .. 387 440 .. 0.76 2 ! 8.1 0.2 0.0038 2 19 117 .. 431 538 .. 405 548 .. 0.64 3 ! 9.6 0.2 0.0013 0.69 214 291 .. 498 579 .. 469 581 .. 0.73 4 ? 5.3 0.0 0.026 14 40 107 .. 550 619 .. 541 634 .. 0.72 5 ! 14.5 0.0 4.2e-05 0.022 35 111 .. 643 718 .. 628 731 .. 0.72 6 ! 22.8 0.0 1.2e-07 6.4e-05 3 109 .. 691 801 .. 689 812 .. 0.83 7 ! 17.0 0.0 7.1e-06 0.0037 24 109 .. 755 847 .. 731 863 .. 0.75 8 ? 2.3 0.0 0.21 1.1e+02 178 244 .. 888 958 .. 885 962 .. 0.67 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.2 Beta-prop_WDR3_2nd 75 tieahegavwsvaltpdekglvtg 98 + + h+++++s++++pd+ ++ +g FUN_000961-T1 398 HYTQHTDDIKSLCVHPDGVRIASG 421 557899999999999999888776 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0038 Beta-prop_WDR3_2nd 19 sesvkiwnvkslecirtieseyalclafv....pgdr..hvlvgtkdG...klevldlasaelletieahegavwsvaltp.dekglvtgg 99 + ++++wn++sl++i i ++y ++f l++++d ++++ d + + l + + ++v +v+ +p +++ +vt+g FUN_000961-T1 431 KPHIRVWNSNSLDTICVIGVDYFEDAIFAlafsNKKSqgSYLASVEDNeyhTITLWDWTRKKKLASARGNMDQVLAVNFSPfESHHFVTCG 521 4478999999999888888766543333211103222334566666651115666777778888888888889999999985556667766 PP Beta-prop_WDR3_2nd 100 aDkkvkfwefelveeees 117 + ++v fwe++ + ++s FUN_000961-T1 522 K-QHVTFWELDDNKLKQS 538 5.6799999987765544 PP == domain 3 score: 9.6 bits; conditional E-value: 0.0013 Beta-prop_WDR3_2nd 214 fahddsvmsvafvp.ktHylfsagkdkkvkyWDadkfekiq...tlegha..gevwalavsskgkfvvsashDksiRlwerteE 291 + d v++v+f p ++H++ ++gk+ +v +W+ d + q +l+ ++ + v ++a s + + v+++ +D si +w + ++ FUN_000961-T1 498 RGNMDQVLAVNFSPfESHHFVTCGKQ-HVTFWELDDNKLKQsrgRLSKNHrpKYVSCIAFSVNCD-VLTGDTDGSICVWPEESN 579 456799******98679*******97.58999877654433112344333235689999998876.679999****99987665 PP == domain 4 score: 5.3 bits; conditional E-value: 0.026 Beta-prop_WDR3_2nd 40 yalclafvpgdrhvlvgtkdGklevldlasaelleti...eahegavwsvaltpdekglvtggaDkkvkfw 107 y+ c+af + + vl g dG++ v +s ++ e++ +ah+++v+++ + p++ l gg+++ v+ w FUN_000961-T1 550 YVSCIAF-SVNCDVLTGDTDGSICVWPEESNQISEELgvrNAHSDSVYALLVLPNDVVLSGGGGESIVRAW 619 4445544.456678888888888888777776666543336888888888888888888888888888777 PP == domain 5 score: 14.5 bits; conditional E-value: 4.2e-05 Beta-prop_WDR3_2nd 35 tieseyalclafvpgdrhvlvgtkdGklevldlasaelletieahegavwsvaltpdekglvtggaDkkvkfwefel 111 +++ + + l + + d+h+ v++ + +l+ l+ a + i+ h ++++ +a +p++ ++vtgg+Dk v++w+ + FUN_000961-T1 643 SLALGTGNQLYIGTVDNHIWVASLNVDLT-SPLKGAVAKSVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQ 718 55555555555555566666665555553.45666777778999999999999999999999999999999998765 PP == domain 6 score: 22.8 bits; conditional E-value: 1.2e-07 Beta-prop_WDR3_2nd 3 Ravalssddklllsa.ssesvkiwnvkslecirtie..seyalclafvpgdrhvlvgtkdGklevldlasaelletieah.egavwsvalt 89 R +a + + +++ s++ v++w++++++++ t + + ++af p v vg k+ ++l+ +++el+ ++++ +++ +++ + FUN_000961-T1 691 RGLAAHPSSPTFVTGgSDKVVRLWHADQHRVVWTNNklGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIKLTSEpPEKISEIQFS 781 666555555555555166789***********999743478999****************************988877662699******* PP Beta-prop_WDR3_2nd 90 pdekglvtggaDkkvkfwef 109 pd++ + g+ D++v ++e+ FUN_000961-T1 782 PDGTHVALGCHDNDVYIYEL 801 ******************97 PP == domain 7 score: 17.0 bits; conditional E-value: 7.1e-06 Beta-prop_WDR3_2nd 24 iwnvkslecirties...eyalclafvpgdrhvlvgtkdGklevldlas....aelletieahegavwsvaltpdekglvtggaDkkvkfw 107 + n+++ e i ++s e+ + f p+ hv +g++d ++ +++l s +l +++ah+++v ++ ++d+++l ++++D ++ fw FUN_000961-T1 755 LLNASTGELIIKLTSeppEKISEIQFSPDGTHVALGCHDNDVYIYELLSegrsVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFW 845 6677777777777652223555678999*****************9965311134445799****************************** PP Beta-prop_WDR3_2nd 108 ef 109 + FUN_000961-T1 846 DA 847 85 PP == domain 8 score: 2.3 bits; conditional E-value: 0.21 Beta-prop_WDR3_2nd 178 vlsldissDsklivtgsaDknikiwGldfGDchks...lfahddsvmsvafvpktHylfsa.gkdkkvkyW 244 v s+d s++ +l++tg n+ ++ + + +h+ vm+v+f + +l+s+ g+d + +W FUN_000961-T1 888 VNSVDRSHNKRLLATGDDFGNVNLYRYPCVSEKAEpwiIKGHSAHVMNVRFLSDDTRLISVgGRDASTLQW 958 66777777777777777777777776655443332222788999999999988777777752577777777 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.1 0.056 29 222 309 .. 386 486 .. 378 499 .. 0.69 2 ? 5.3 0.0 0.027 14 84 198 .. 521 633 .. 514 643 .. 0.71 3 ! 34.5 0.0 3.5e-11 1.8e-08 148 271 .. 676 803 .. 646 809 .. 0.84 4 ? 4.3 0.1 0.053 28 237 275 .. 815 853 .. 806 857 .. 0.90 5 ? -2.4 0.1 6 3.1e+03 237 269 .. 927 960 .. 925 962 .. 0.75 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.056 Beta-prop_WDR36-Utp21_2nd 222 ilvvDidtrrvvRkfsghknritDltfspdarWlitasm.....Ds..tirtwd...lpsgkliDvflvesaatslsls...pt 292 ++++D + + R+++ h+ i+ l+ pd+ + + + D+ ir+w+ l + ++i v e+a +l++s ++ FUN_000961-T1 386 VVIYDEELH-HQRHYTQHTDDIKSLCVHPDGVRIASGQVkghgdDAkpHIRVWNsnsLDTICVIGVDYFEDAIFALAFSnkkSQ 468 555565554.56*******************999987653333243336****833345555555555679999****944446 PP Beta-prop_WDR36-Utp21_2nd 293 gdfLatahvdd.lgvyLw 309 g +La++ ++ ++ Lw FUN_000961-T1 469 GSYLASVEDNEyHTITLW 486 899999876541355555 PP == domain 2 score: 5.3 bits; conditional E-value: 0.027 Beta-prop_WDR36-Utp21_2nd 84 glkkattWsyqkkklGkhklkperlkkkkvvataveis.sCGnfvviGyssGhvdrfNlqSglhRgsygkekahkkavrGvavd 166 g++++t W+ + +kl + + + ++ ++ k + +++ s +C v+ G ++G++ ++ S +++g +ah+++v + v FUN_000961-T1 521 GKQHVTFWELDDNKLKQSRGRLSKNHRPK-YVSCIAFSvNCD--VLTGDTDGSICVWPEESNQISEELGVRNAHSDSVYALLVL 601 56677888888877777666554444433.344555441453..6789999******************99*******999987 PP Beta-prop_WDR36-Utp21_2nd 167 alnqvvitagadkklkfwkfkskklletlkle 198 v+ +g ++ ++ w + k + ++++l+ FUN_000961-T1 602 PNDVVLSGGGGESIVRAWYKRPKLIPTNVELK 633 65554445567888899987777666666665 PP == domain 3 score: 34.5 bits; conditional E-value: 3.5e-11 Beta-prop_WDR36-Utp21_2nd 148 gsygk..ekahkkavrGvavdalnqvvitagadkklkfwkfkskkll.etlkleasisklvlhressllavalddfsilvvDid 228 g+ +k + h++ +rG+a + + +t+g+dk +++w+ +++++ ++ kl ++i++ ++h ssl+av + + ++ FUN_000961-T1 676 GAVAKsvIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVwTNNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNAS 759 4555422478*******************************99877626789******************************** PP Beta-prop_WDR36-Utp21_2nd 229 trrvvRkfsgh.knritDltfspdarWlitasmDstirtwdlps 271 t +++ k++ +i+++ fspd+ + D + +++l s FUN_000961-T1 760 TGELIIKLTSEpPEKISEIQFSPDGTHVALGCHDNDVYIYELLS 803 *99888887652789**************999999999999865 PP == domain 4 score: 4.3 bits; conditional E-value: 0.053 Beta-prop_WDR36-Utp21_2nd 237 sghknritDltfspdarWlitasmDstirtwdlpsgkli 275 + h+++++ l +s+d+ l ++s+D + wd +g+ i FUN_000961-T1 815 KAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQI 853 6899****************************9988766 PP == domain 5 score: -2.4 bits; conditional E-value: 6 Beta-prop_WDR36-Utp21_2nd 237 sghknritDltf.spdarWlitasmDstirtwdl 269 +gh+++++ + f s d+r + + D++ w + FUN_000961-T1 927 KGHSAHVMNVRFlSDDTRLISVGGRDASTLQWKI 960 799*****99984556666666678988888876 PP >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 6.4e-06 0.0033 4 32 .. 93 129 .. 91 160 .. 0.69 2 ! 26.8 0.1 1.4e-08 7.1e-06 15 65 .. 221 269 .. 205 271 .. 0.90 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 6.4e-06 EF-hand_7 4 lkeaFkllDsdgdGyldveelkkllrkl........e 32 +++F++lD+d++G+++ eel ++l + FUN_000961-T1 93 VQKKFSSLDTDNSGRITSEELSQVLLNNqifilgktL 129 5889******************988754444333330 PP == domain 2 score: 26.8 bits; conditional E-value: 1.4e-08 EF-hand_7 15 gdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlel 65 ++G +d +elk l++ + + p+s+ +e+l+ fD+d+dG +++ EF ++ FUN_000961-T1 221 RNGLIDNKELKMLCK--RHNLPISRSLLEKLVSRFDVDGDGWVNLREFSKF 269 79*********8888..9******************************987 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.3 0.46 2.4e+02 54 102 .. 438 491 .. 394 504 .. 0.55 2 ! 9.6 0.0 0.001 0.54 14 105 .. 502 582 .. 496 601 .. 0.74 3 ! 13.2 0.0 8.7e-05 0.046 124 209 .. 681 766 .. 675 780 .. 0.89 4 ! 13.4 0.2 7.6e-05 0.039 126 166 .. 814 854 .. 775 864 .. 0.81 5 ! 7.7 0.1 0.004 2.1 72 160 .. 887 961 .. 884 964 .] 0.86 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.46 Beta-prop_CAF1B_HIR1 54 eegkvklelladltrhqkavnvvrfsps...gelLasgdDes..viiiWklkee 102 +++++++ ++ ++ + a+ + fs++ g++Las +D+ +i +W +++ FUN_000961-T1 438 NSNSLDTICVIGVDYFEDAIFALAFSNKksqGSYLASVEDNEyhTITLWDWTRK 491 333344445555555555666666665311156777777764224666665555 PP == domain 2 score: 9.6 bits; conditional E-value: 0.001 Beta-prop_CAF1B_HIR1 14 dpvlsvDiqkksekkeeeevlrlasgGaDshvliWkvkieeegkvklelladltrhqkavnvvrfspsgelLasgdDesviiiWklkee 102 d vl+v++++ + +++ ++G+ +hv+ W++ ++ ++ + l ++ k v ++ fs + ++L +gd ++ i +W ++++ FUN_000961-T1 502 DQVLAVNFSPFE-------SHHFVTCGK-QHVTFWELDDNKLKQSRGRLSK--NHRPKYVSCIAFSVNCDVL-TGDTDGSICVWPEESN 579 555555555443.......356788886.79******99877666655443..355799***********99.69999******99888 PP Beta-prop_CAF1B_HIR1 103 eee 105 + + FUN_000961-T1 580 QIS 582 653 PP == domain 3 score: 13.2 bits; conditional E-value: 8.7e-05 Beta-prop_CAF1B_HIR1 124 kvlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkvvar 209 v++Gh +d+ l+ p+s ++++g D + lW+ ++ + + ++ + +q+ a+ P +++va r +++++t +++ + FUN_000961-T1 681 SVIQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIK 766 689*************************************999999999***************9988888888888887777665 PP == domain 4 score: 13.4 bits; conditional E-value: 7.6e-05 Beta-prop_CAF1B_HIR1 126 lrGhledvyDlswspdskklisgsvDntailWdvekgkkla 166 + h+ v l ws+d+++l s s D + Wd +g++++ FUN_000961-T1 814 CKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQIT 854 47799999999999999999999999999999999888765 PP == domain 5 score: 7.7 bits; conditional E-value: 0.004 Beta-prop_CAF1B_HIR1 72 avnvvrfspsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlswspdskklis.gsvDntailWdv 159 vn v s++++lLa+gdD +++ +++ + e+ e w+ ++Gh v+++ + +d+++lis g D +++ W++ FUN_000961-T1 887 DVNSVDRSHNKRLLATGDDFGNVNLYRYPCVS-----------EKAEPWI----IKGHSAHVMNVRFLSDDTRLISvGGRDASTLQWKI 960 5999999***************9999876654...........4678895....79**********99999999987889999999988 PP Beta-prop_CAF1B_HIR1 160 e 160 FUN_000961-T1 961 V 961 6 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.3 1.6e+02 273 307 .. 388 425 .. 384 428 .. 0.74 2 ! 7.1 0.1 0.0071 3.7 74 191 .. 481 595 .. 451 612 .. 0.70 3 ? 3.8 0.0 0.068 36 14 80 .. 552 620 .. 541 661 .. 0.76 4 ! 9.0 0.0 0.0018 0.95 281 317 .. 683 719 .. 678 726 .. 0.91 5 ! 7.1 0.0 0.0071 3.7 144 216 .. 727 800 .. 717 805 .. 0.83 6 ! 8.8 0.2 0.0021 1.1 49 90 .. 815 856 .. 813 872 .. 0.86 7 ? 0.1 0.0 0.91 4.7e+02 151 206 .. 890 948 .. 882 959 .. 0.67 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.3 EIF3I 273 ifeeeigr...vkGHFGPintlavhPdGksyasggEdG 307 i++ee+ + H i +l vhPdG +asg G FUN_000961-T1 388 IYDEELHHqrhYTQHTDDIKSLCVHPDGVRIASGQVKG 425 566666541113468889***************98666 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0071 EIF3I 74 ntvklWdvetGkelktletk.tavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghedg 168 +t+ lWd + k+l++ + + +v +v+fs+ +++ +++ k+ ++++ +++d++ ++++ ++ + ++ k+ +++ +++ ++tg +dg FUN_000961-T1 481 HTITLWDWTRKKKLASARGNmDQVLAVNFSPFESHHFVTCGKQ-----HVTFWELDDNKLKQSRGRLS-KN-HRPKYVSCIAFSVNCDVLTGDTDG 569 47899**9999999988765158999****9999888877654.....57788887776655555444.33.344555555555677899****** PP EIF3I 169 eiskydlktgeklks...vkehekqi 191 +i+ + +++++ ++ ++h++++ FUN_000961-T1 570 SICVWPEESNQISEElgvRNAHSDSV 595 *****998887766511134555555 PP == domain 3 score: 3.8 bits; conditional E-value: 0.068 EIF3I 14 tqikynreGDllfsvakdkkasvwysen...GerlGtyeGheGavwsidvdsettllvtgsadntvklWd 80 + i ++ + D+l + d +++vw e e lG + h+ +v+++ v + l g +++ v+ W FUN_000961-T1 552 SCIAFSVNCDVL-TGDTDGSICVWPEESnqiSEELGVRNAHSDSVYALLVLPNDVVLSGGGGESIVRAWY 620 556677777765.567799999997654233699999999999999999999999999999999999995 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0018 EIF3I 281 vkGHFGPintlavhPdGksyasggEdGyvrvhefdks 317 ++GH + la hP++ ++++gg d vr+ + d++ FUN_000961-T1 683 IQGHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQH 719 799****************************999875 PP == domain 5 score: 7.1 bits; conditional E-value: 0.0071 EIF3I 144 veeskvtvalwsaldktiitghedgeiskydlktgeklks.vkehekqitdlqlskdktylitaskDktaklld 216 + s++++a++ ++ + +g ++ + +++tge + + ++e ++i+++q+s+d t + ++D+ +++ FUN_000961-T1 727 KLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIKlTSEPPEKISEIQFSPDGTHVALGCHDNDVYIYE 800 44589999****************999********987661566789***************999999887776 PP == domain 6 score: 8.8 bits; conditional E-value: 0.0021 EIF3I 49 eGheGavwsidvdsettllvtgsadntvklWdvetGkelktl 90 + h+ +v +d +++ ++l ++s+d ++ +Wd +G++++ FUN_000961-T1 815 KAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQITAS 856 57999*******************************999754 PP == domain 7 score: 0.1 bits; conditional E-value: 0.91 EIF3I 151 valwsaldktiitghedgeiskydl...ktgeklksvkehekqitdlqlskdktylita 206 ++ s++++ + tg + g+++ y +++ + +k h++++ ++++ +d t li+ FUN_000961-T1 890 SVDRSHNKRLLATGDDFGNVNLYRYpcvSEKAEPWIIKGHSAHVMNVRFLSDDTRLISV 948 55567777788888888888888751113333444578889999999988888888875 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0032 1.7 203 249 .. 490 535 .. 451 548 .. 0.83 2 ! 16.9 0.0 8.9e-06 0.0046 167 277 .. 503 610 .. 479 611 .. 0.75 3 ? -1.1 0.0 2.7 1.4e+03 231 268 .. 703 740 .. 695 750 .. 0.53 4 ! 19.5 0.0 1.4e-06 0.00072 162 251 .. 769 854 .. 741 864 .. 0.82 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0032 Beta-prop_RIG_2nd 203 etlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepek 249 +++k a+ + +++ +v++s+ +s+ +++++ +v W+l++++ FUN_000961-T1 490 RKKKLASARGNMDQVLAVNFSPFESHHFVTCGK-QHVTFWELDDNKL 535 456666788899******************998.99*****998875 PP == domain 2 score: 16.9 bits; conditional E-value: 8.9e-06 Beta-prop_RIG_2nd 167 yitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepek.ee..ltit 255 + +++sp+es ++ +++++ ++ e+++++ ++ ++ ++++ + ++++++s + +l+ + dg+++vW e+++ ee + ++ FUN_000961-T1 503 QVLAVNFSPFESHHFVTCGKQH-VTFWELDDNKL-KQSRGRLSKNHRPKYVSCIAFSVNC--DVLTGDTDGSICVWPEESNQIsEElgVRNA 590 566789*********9999875.67789985544.455556777778889*******876..589***********9988886344224556 PP Beta-prop_RIG_2nd 256 ykcpmlcglFlPtdenivlcgG 277 ++ ++++ l lP d +vl+gG FUN_000961-T1 591 HSDSVYALLVLPND--VVLSGG 610 77778888888864..677666 PP == domain 3 score: -1.1 bits; conditional E-value: 2.7 Beta-prop_RIG_2nd 231 lsfsidgkvkvWdleepekeeltitykcpmlcglFlPt 268 ++ + d v++W ++++ + ++ + + ++ F P FUN_000961-T1 703 VTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPY 740 55555555555555555554444444444444444443 PP == domain 4 score: 19.5 bits; conditional E-value: 1.4e-06 Beta-prop_RIG_2nd 162 allsryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekee 251 + ++ i++i++sp +++A +d+ ++i+e+ +e r+++ k+ +a+ s++ + ws+ +nl s+s d ++ Wd ++e+ + FUN_000961-T1 769 SEPPEKISEIQFSPDG-THVALGCHDNDVYIYELLSEGRSVSL--KVRCKAHTSSVSHLDWSKDGENLQ-STSTDYELLFWDALQGEQIT 854 4456889******987.99****************88776665..67788999**********999865.55999*******99998865 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.77 4e+02 35 61 .. 400 426 .. 384 445 .. 0.87 2 ? -1.2 0.1 6.6 3.4e+03 35 90 .. 498 558 .. 474 580 .. 0.76 3 ! 13.7 0.0 0.00015 0.079 23 79 .. 715 770 .. 703 773 .. 0.83 4 ! 9.7 0.0 0.0027 1.4 39 67 .. 773 801 .. 769 813 .. 0.87 5 ! 8.2 0.0 0.008 4.2 35 76 .. 815 856 .. 805 873 .. 0.87 6 ? -0.4 0.0 3.8 2e+03 35 65 .. 882 912 .. 868 919 .. 0.85 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.77 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdge 61 +++ ++sl+ +pdG +a + +g+ FUN_000961-T1 400 TQHTDDIKSLCVHPDGVRIASGQVKGH 426 457889**************9988775 PP == domain 2 score: -1.2 bits; conditional E-value: 6.6 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdk.....itcleWae 90 ++ +v +++++p + v + + +v + + + kl +s s++ ++c+ +++ FUN_000961-T1 498 RGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSRGRLSKNhrpkyVSCIAFSV 558 5566677778888888888888888888888888877777665555555667777777765 PP == domain 3 score: 13.7 bits; conditional E-value: 0.00015 ANAPC4_WD40 23 RlnwqrvwklseekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsak 79 + +rv + ++k +se+++ a++p l av++++ ll++++g+l+ +l+++ FUN_000961-T1 715 HADQHRVVWT-NNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIIKLTSE 770 4455555444.59**************************************999876 PP == domain 4 score: 9.7 bits; conditional E-value: 0.0027 ANAPC4_WD40 39 sevtslaWkpdGklLavaysdgevrlldv 67 +++++++++pdG+ a +++d+ v +++ FUN_000961-T1 773 EKISEIQFSPDGTHVALGCHDNDVYIYEL 801 79***********************9986 PP == domain 5 score: 8.2 bits; conditional E-value: 0.008 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgklvhsl 76 ++++s+v++l W++dG+ L d e+ + d+ +g+ + FUN_000961-T1 815 KAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQITAS 856 67899****************************999988765 PP == domain 6 score: -0.4 bits; conditional E-value: 3.8 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrll 65 +++ v+s+ +++ +lLa + + g+v+l+ FUN_000961-T1 882 GADGTDVNSVDRSHNKRLLATGDDFGNVNLY 912 5678889999999999999999999999987 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 2.6e-06 0.0014 3 26 .. 94 117 .. 92 121 .. 0.90 2 ? 2.0 0.0 0.62 3.2e+02 13 27 .. 221 235 .. 219 239 .. 0.87 3 ! 12.3 0.0 0.0003 0.16 2 27 .. 246 271 .. 245 279 .. 0.88 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 2.6e-06 EF-hand_6 3 reaFklfDkdgdGyisleElraal 26 ++ F+ +D+d++G+i+ eEl ++l FUN_000961-T1 94 QKKFSSLDTDNSGRITSEELSQVL 117 678*****************9998 PP == domain 2 score: 2.0 bits; conditional E-value: 0.62 EF-hand_6 13 gdGyisleElraalr 27 ++G i+ +El+ +++ FUN_000961-T1 221 RNGLIDNKELKMLCK 235 79*********9998 PP == domain 3 score: 12.3 bits; conditional E-value: 0.0003 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 l+++ ++fD+dgdG ++l E+ ++l FUN_000961-T1 246 LEKLVSRFDVDGDGWVNLREFSKFLG 271 5677789***************9996 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 1.4 7.1e+02 84 124 .. 385 425 .. 379 441 .. 0.79 2 ! 7.1 0.0 0.005 2.6 76 353 .. 517 577 .. 471 597 .. 0.57 3 ! 21.1 0.2 3e-07 0.00015 20 133 .. 735 849 .. 717 874 .. 0.79 4 ? 4.7 0.0 0.028 14 325 355 .. 887 917 .. 882 960 .. 0.83 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.4 Beta-prop_IFT140_1st 84 vlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksG 124 v+v+ +++ ++++ + h+ +i+ l+ g r++sg +G FUN_000961-T1 385 VVVIYDEELHHQRHYTQHTDDIKSLCVHPDGVRIASGQVKG 425 555555555666666779999****9999999999998877 PP == domain 2 score: 7.1 bits; conditional E-value: 0.005 Beta-prop_IFT140_1st 76 avgwesGevlvlneqdkelte....lpklhkaeitvlewssngsrLvsgdksGvlvvWkldqrGrlqqspllkhelkkpltqcifrppk 160 v+ + v+ ++ d++l++ l+k h FUN_000961-T1 517 FVTCGKQHVTFWELDDNKLKQsrgrLSKNH----------------------------------------------------------- 546 444444445555444444433111123333........................................................... PP Beta-prop_IFT140_1st 161 peedlaqlakaavsGdekaldmfnwkkskkgsllklgsqeelsffvgtadGsvyyvdekgktsqvlsvdssvkkLlylekkevLvvvTe 249 FUN_000961-T1 - ----------------------------------------------------------------------------------------- - ......................................................................................... PP Beta-prop_IFT140_1st 250 nllLsqytvspegeaeevlkvKLsgktgkeadiiwaekglLitatgesvirlwdlerddnyvLsldeklgfekgEaincvsyckakgiL 338 + ++c++++ + ++L FUN_000961-T1 547 ------------------------------------------------------------------------RPKYVSCIAFSVNCDVL 563 ........................................................................33445555555555555 PP Beta-prop_IFT140_1st 339 aaGtnkGrvalwkkv 353 ++ t+ G + +w + FUN_000961-T1 564 TGDTD-GSICVWPEE 577 44443.555555444 PP == domain 3 score: 21.1 bits; conditional E-value: 3e-07 Beta-prop_IFT140_1st 20 iaWhkesplLAvasvseesgGsvdlyleegekvedakiersvqvtvlsWHPtkkilavgwesGevlvlneqdkel....telpklhkae 104 a h+ s+l+Av+ ++ G l +ge + + + e + + + ++ P +++a+g + +v++++ ++ + k+h+++ FUN_000961-T1 735 AAFHPYSSLVAVGF---KKRGWALLNASTGELIIKLTSEPPEKISEIQFSPDGTHVALGCHDNDVYIYELLSEGRsvslKVRCKAHTSS 820 46788888888887...5678999999****************************************986554331111344589**** PP Beta-prop_IFT140_1st 105 itvlewssngsrLvsgdksGvlvvWkldq 133 ++ l+ws+ g++L s+ + l+ W + q FUN_000961-T1 821 VSHLDWSKDGENLQSTSTDYELLFWDALQ 849 *************************8755 PP == domain 4 score: 4.7 bits; conditional E-value: 0.028 Beta-prop_IFT140_1st 325 aincvsyckakgiLaaGtnkGrvalwkkvae 355 +n+v+ +++k +La+G + G+v l+++ FUN_000961-T1 887 DVNSVDRSHNKRLLATGDDFGNVNLYRYPCV 917 5889999999999999999999999998544 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 1.1e-05 0.006 3 26 .. 94 117 .. 92 119 .. 0.88 2 ? 3.3 0.0 0.19 99 13 28 .. 221 236 .. 221 237 .. 0.90 3 ! 9.9 0.1 0.0015 0.77 2 27 .. 246 271 .. 245 273 .. 0.87 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 1.1e-05 EF-hand_1 3 keiFrefDkDgdGkIdfeEfkell 26 ++ F+ +D+D++G+I+ eE+ ++l FUN_000961-T1 94 QKKFSSLDTDNSGRITSEELSQVL 117 667999**************9986 PP == domain 2 score: 3.3 bits; conditional E-value: 0.19 EF-hand_1 13 gdGkIdfeEfkellkk 28 ++G Id +E+k l+k+ FUN_000961-T1 221 RNGLIDNKELKMLCKR 236 69**********9986 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0015 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellk 27 l+++ + fD+DgdG +++ Ef ++l FUN_000961-T1 246 LEKLVSRFDVDGDGWVNLREFSKFLG 271 5778889**************99985 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 2.1e-06 0.0011 3 25 .] 96 117 .. 95 118 .. 0.90 2 ? 0.2 0.0 1.6 8.5e+02 12 23 .. 221 232 .. 221 234 .. 0.87 3 ! 8.8 0.1 0.0032 1.7 7 25 .] 252 270 .. 248 270 .. 0.93 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 2.1e-06 EF-hand_5 3 dtFraiDlNgDGkIskeELkrll 25 + F +D++++G+I+ eEL ++l FUN_000961-T1 96 K-FSSLDTDNSGRITSEELSQVL 117 5.999**************9974 PP == domain 2 score: 0.2 bits; conditional E-value: 1.6 EF-hand_5 12 gDGkIskeELkr 23 ++G I+ +ELk FUN_000961-T1 221 RNGLIDNKELKM 232 5899******97 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0032 EF-hand_5 7 aiDlNgDGkIskeELkrll 25 +D++gDG ++ E+ ++l FUN_000961-T1 252 RFDVDGDGWVNLREFSKFL 270 69*************9986 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.61 3.2e+02 219 249 .. 399 424 .. 389 427 .. 0.79 2 ! 12.8 0.0 0.00014 0.075 184 257 .. 549 621 .. 516 660 .. 0.79 3 ? 6.1 0.0 0.016 8.5 181 221 .. 685 725 .. 674 794 .. 0.79 4 ? 2.2 0.1 0.25 1.3e+02 193 258 .. 782 848 .. 772 855 .. 0.71 5 ! 6.9 0.0 0.0089 4.6 196 257 .. 898 960 .. 885 963 .. 0.82 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.61 Beta-prop_WDR75_1st 219 ytystlhwhhdavsslvftpeGtnllsGGve 249 yt h d ++sl+ p+G+++ sG v+ FUN_000961-T1 399 YT-----QHTDDIKSLCVHPDGVRIASGQVK 424 33.....48899***************9875 PP == domain 2 score: 12.8 bits; conditional E-value: 0.00014 Beta-prop_WDR75_1st 184 naftcvachpkddciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnllsGGvesvlvqwry 257 ++c+a + d + tG dG i +w + +++ h d+v +l p+ + l GG es++ w FUN_000961-T1 549 KYVSCIAFSVNCD-VLTGDTDGSICVWPEESNQISEELGVRNAHSDSVYALLVLPNDVVLSGGGGESIVRAWYK 621 4566777665555.67************99999999999********************999******999954 PP == domain 3 score: 6.1 bits; conditional E-value: 0.016 Beta-prop_WDR75_1st 181 GaknaftcvachpkddciatGhedGkirlwrnfnqkkeyty 221 G + +a+hp tG d +rlw +++ +t FUN_000961-T1 685 GHCQDLRGLAAHPSSPTFVTGGSDKVVRLWHADQHRVVWTN 725 6666778899********************99888876665 PP == domain 4 score: 2.2 bits; conditional E-value: 0.25 Beta-prop_WDR75_1st 193 pkddciatGhedGkirlwrnfnqkkeytyst.lhwhhdavsslvftpeGtnllsGGvesvlvqwrye 258 p+ +a G +d + ++ +++ + + + h ++vs+l ++ +G nl s + l+ w FUN_000961-T1 782 PDGTHVALGCHDNDVYIYELLSEGRSVSLKVrCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDAL 848 5555666666677777777666666666543156788999999999999999999999988888765 PP == domain 5 score: 6.9 bits; conditional E-value: 0.0089 Beta-prop_WDR75_1st 196 dciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnlls.GGvesvlvqwry 257 +atG + G++ l+r ++ ++ h v++++f ++ t+l+s GG ++ +qw++ FUN_000961-T1 898 RLLATGDDFGNVNLYRYPCVSEKAEPWIIKGHSAHVMNVRFLSDDTRLISvGGRDASTLQWKI 960 5689***********97554444444567789999**************9799999*****96 PP >> DUF5580_M Family of unknown function (DUF5580) middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.0 1.4e-09 7.1e-07 10 88 .. 196 276 .. 188 281 .. 0.88 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 1.4e-09 DUF5580_M 10 lktakgklnlenLnlsfrk..eDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvelLsrassd 88 l + g+ ++L+ sf+k e + Gl+ +++++ +C++h l ++ slle l++ d+ + ++ +++ ++L +a+s FUN_000961-T1 196 LMQNGGNWTFNELKASFQKyyEKGARNGLIDNKELKMLCKRHNLPISRSLLEKLVSRFDVDGDGWVNLREFSKFLGKAVSV 276 55566788899*******955667899***************************************************985 PP >> RMC1_N Regulator of MON1-CCZ1 complex, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.029 15 10 99 .. 472 562 .. 467 569 .. 0.75 2 ! 20.3 0.0 1.2e-06 0.0006 38 99 .. 771 832 .. 754 847 .. 0.86 3 ? -1.8 0.0 8.1 4.2e+03 40 93 .. 886 938 .. 883 948 .. 0.67 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.029 RMC1_N 10 vfavrsggvlgvvvkgpdekeplsfriedkgpvlsikfSlDkkilavqrssksvefinfaedetsveysqsck.sksakilgfvWtsnnei 99 + +v++++ ++ + ++k++l + + +vl++ fS+ ++ v ++ v f+++++++ +++ +k + + + + ++ n+++ FUN_000961-T1 472 LASVEDNEYHTITLWDWTRKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSRGRLSKnHRPKYVSCIAFSVNCDV 562 5678888899999999999999999999999****************************88775443322222022334455555555555 PP == domain 2 score: 20.3 bits; conditional E-value: 1.2e-06 RMC1_N 38 dkgpvlsikfSlDkkilavqrssksvefinfaedetsveysqscksksakilgfvWtsnnei 99 ++ i+fS+D +a+ ++++v ++++ ++ sv+ + +ck++++++ + W++ e FUN_000961-T1 771 PPEKISEIQFSPDGTHVALGCHDNDVYIYELLSEGRSVSLKVRCKAHTSSVSHLDWSKDGEN 832 55789***************************************************987665 PP == domain 3 score: -1.8 bits; conditional E-value: 8.1 RMC1_N 40 gpvlsikfSlDkkilavqrssksvefinfaedetsveysqscksksakilgfvW 93 +v+s+ S +k++la + +v+++++ + +++ k++sa+++ + + FUN_000961-T1 886 TDVNSVDRSHNKRLLATGDDFGNVNLYRY-PCVSEKAEPWIIKGHSAHVMNVRF 938 67999999999999998888888888776.444444444555566666665555 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.32 1.7e+02 211 300 .. 497 586 .. 452 609 .. 0.64 2 ? -2.2 0.0 5.5 2.9e+03 312 326 .. 648 662 .. 628 667 .. 0.69 3 ! 22.5 0.0 1.7e-07 9e-05 29 167 .. 708 851 .. 693 959 .. 0.69 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.32 Beta-prop_ACSF4 211 vktkgpiFsspvlvkseekivfgshdgllyclsvs.gellwkve.l...dseifatPfvfeesegsnekllavastdGklflldletgevlasl 299 ++ + + +++ e++ ++++ +++++ +++ ++l+ + l ++ + ++++f+ + +++ +tdG+++++ +e+ ++ +l FUN_000961-T1 497 ARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDdNKLKQSRGrLsknHRPKYVSCIAFSV-N----CDVLTGDTDGSICVWPEESNQISEEL 585 44444444555566667777888888888888885255544432121113456777777772.2....34667999999999999988887665 PP Beta-prop_ACSF4 300 k 300 FUN_000961-T1 586 G 586 4 PP == domain 2 score: -2.2 bits; conditional E-value: 5.5 Beta-prop_ACSF4 312 lgnrllvGcRDnnly 326 gn+l++G+ Dn++ FUN_000961-T1 648 TGNQLYIGTVDNHIW 662 467778888887764 PP == domain 3 score: 22.5 bits; conditional E-value: 1.7e-07 Beta-prop_ACSF4 29 sgkivcvdletgeviweie.lpdriEssacvskdgklvvvGcydgklycldlatgeilwkfktgdaiK.sspvidsesglvvvgsydknlyald 120 ++++ +++++v+w+ + l+++i++ a +++ ++lv vG ++ l+++tge++ k +++ K s+ + ++ + v +g++d+ +y ++ FUN_000961-T1 708 DKVVRLWHADQHRVVWTNNkLGSEIQAAA-FHPYSSLVAVGFKKRGWALLNASTGELIIKLTSEPPEKiSEIQFSPDGTHVALGCHDNDVYIYE 800 4555667889999***7655*******65.79*******************************9988834555678889************999 PP Beta-prop_ACSF4 121 ves..gklvwklklg..gsifsspllskskesvlvatldGtvaalseesge 167 + s +++ k++++ s +s +sk+ e++ +++d +++ ++ +ge FUN_000961-T1 801 LLSegRSVSLKVRCKahTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGE 851 855324445566665215666666677788888888888887777665554 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.1 0.012 6 61 144 .. 503 580 .. 460 621 .. 0.73 2 ? 6.3 0.1 0.012 6.2 20 129 .. 690 759 .. 639 767 .. 0.54 3 ! 16.1 0.0 1.2e-05 0.0065 14 144 .. 726 851 .. 719 864 .. 0.79 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.012 Beta-prop_Aladin 61 svaslaWrPlsaselavacesgvlvWtvdptslatrpssssaqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdvaket 144 +v ++++ P+ + ++ +++v W++d + l +s + + k++ + v ++a+s + d+L +d si vW + ++ FUN_000961-T1 503 QVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLK--QSRGRLS--KNHRPKYVSCIAFSVNCDVLT--GDTDGSICVWPEESNQ 580 5667777787777777777888888888886653..3333322..333334488888888888885..4678888888766655 PP == domain 2 score: 6.3 bits; conditional E-value: 0.012 Beta-prop_Aladin 20 iralaWhphttklavallddsirvytsesslvplLkhklqksvaslaWrPlsaselavacesgvlvWtvdptsla.tr.pssssaqvLkrpgh 110 +r la +P s + + + ++ v +W+ d+ ++ t + s +q + + FUN_000961-T1 690 LRG------------------------------------------LAAHPSSPTFVTGGSDKVVRLWHADQHRVVwTNnKLGSEIQAAAFHPY 740 333..........................................566666666666666666666666655443122022344444444555 PP Beta-prop_Aladin 111 spvtsvaWspkGdlLvsas 129 s+++ v ++ +G L+ as FUN_000961-T1 741 SSLVAVGFKKRGWALLNAS 759 5566666666666666665 PP == domain 3 score: 16.1 bits; conditional E-value: 1.2e-05 Beta-prop_Aladin 14 dWkesairalaWhphttklavallddsirvytse.sslvplLkhklqksvaslaWrPlsaselavace.sgvlvWtvdptslatrpssssaqv 104 + s i+a a+hp+ + +av + + +++ +l+ L ++ ++++ +++ P +++a +c+ + v ++++ ++ + + FUN_000961-T1 726 NKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNAStGELIIKLTSEPPEKISEIQFSPDG-THVALGCHdNDVYIYELLSEGRSVSLKVRC--- 814 455689*****************99998888776378999999**************85.678999973579999875544443333333... PP Beta-prop_Aladin 105 LkrpghspvtsvaWspkGdlLvsaspvdtsilvWdvaket 144 + + s+v + Ws +G+ L s+s +d ++l Wd + + FUN_000961-T1 815 --KAHTSSVSHLDWSKDGENLQSTS-TDYELLFWDALQGE 851 ..5566899*************998.699******86554 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.0015 0.77 61 134 .. 503 574 .. 482 593 .. 0.84 2 ! 13.9 0.0 6.4e-05 0.033 54 122 .. 766 833 .. 718 839 .. 0.82 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.0015 Beta-prop_HPS5 61 aistvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsvt 134 ++ v +sp e v+ + v+ +el+ ++k k +r s++h+ + v++++ + ++ v +Gd+ G++ v FUN_000961-T1 503 QVLAVNFSPFESHHFVTCGKQHVTFWELD-DNKLKQSRGRLSKNHRPKYVSCIAFSVNC-DVLTGDTDGSICVW 574 566788999999999999999*******9.889999999****************9988.5889*****99886 PP == domain 2 score: 13.9 bits; conditional E-value: 6.4e-05 Beta-prop_HPS5 54 lltake.gaistvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrv 122 lt + +is++ +spd va++ ++ v++ el ++ ++ l + + + s v+ L W+++++++ FUN_000961-T1 766 KLTSEPpEKISEIQFSPDGTHVALGCHDNDVYIYELL--SEGRSVSLKVRCKAHTSSVSHLDWSKDGENL 833 444433379***************************8..777888888888888999********98876 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.019 10 49 157 .. 468 582 .. 458 598 .. 0.65 2 ? 4.6 0.0 0.036 19 60 148 .. 708 798 .. 701 801 .. 0.81 3 ! 10.1 0.1 0.00077 0.4 9 82 .. 783 861 .. 777 872 .. 0.62 4 ? 1.8 0.0 0.27 1.4e+02 90 143 .. 894 952 .. 886 956 .. 0.70 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.019 Beta-prop_WDR19_1st 49 dgdlLaiiqeks.slvllwdantkktskldtglkdkltfllWskkspiLavGtskGnlllYnkktskkipilGk....Hs.kkItcgaws 132 +g++La +++++ ++++lwd ++kk+ g d++ ++ s ++ v+ k ++++++ +k G+ H+ k + c a+s FUN_000961-T1 468 QGSYLASVEDNEyHTITLWDWTRKKKLASARGNMDQVLAVNFSPFESHHFVTCGKQHVTFWELDDNKLKQSRGRlsknHRpKYVSCIAFS 557 677777666554267888888888887777777778888888877777777777777777765555544444431112322557788888 PP Beta-prop_WDR19_1st 133 kenlLalgseDktltisnaeGdtlk 157 + + +g +D ++ + +e+++++ FUN_000961-T1 558 VNCDVLTGDTDGSICVWPEESNQIS 582 7777777888888888777777765 PP == domain 2 score: 4.6 bits; conditional E-value: 0.036 Beta-prop_WDR19_1st 60 sslvllwdantkktskldtglkdkltfllWskkspiLavGtskGnlllYnkktskki.pilGkHskkItcgawsken.lLalgseDktlt 147 ++v lw+a+++++ +++l +++++ + s+++avG +k +l n +t i + kI ++s ++ +alg +D+ + FUN_000961-T1 708 DKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSLVAVGFKKRGWALLNASTGELIiKLTSEPPEKISEIQFSPDGtHVALGCHDNDVY 797 57899****************999****************99988888888887765156667789999999997752689999998776 PP Beta-prop_WDR19_1st 148 i 148 i FUN_000961-T1 798 I 798 5 PP == domain 3 score: 10.1 bits; conditional E-value: 0.00077 Beta-prop_WDR19_1st 9 sgnylavagknkvvkiyd..rqGelvd.eiklk...gkctaleWdkdgdlLaiiqeksslvllwdantkktskldtglkd 82 +g+++a+ ++++ v+iy+ +G+ v+ +++ k +++++l+W+kdg+ L ++++ +l+wda + ++ + ++l++ FUN_000961-T1 783 DGTHVALGCHDNDVYIYEllSEGRSVSlKVRCKahtSSVSHLDWSKDGENLQSTSTD-YELLFWDALQGEQITASASLRN 861 678888888888888887333444433123322222567888888888888877665.4466788877777666666665 PP == domain 4 score: 1.8 bits; conditional E-value: 0.27 Beta-prop_WDR19_1st 90 skkspiLavGtskGnlllYnk..ktskkip.ilGkHskkItcgawsken..lLalgseD 143 s+++ +La G++ Gn+ lY ++k p i+ Hs +++ + +++ l+ +g+ D FUN_000961-T1 894 SHNKRLLATGDDFGNVNLYRYpcVSEKAEPwIIKGHSAHVMNVRFLSDDtrLISVGGRD 952 8999*************997622466777734455888888888866542245556655 PP >> DUF5580 Family of unknown function (DUF5580) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 3.7e-05 0.019 18 72 .. 86 140 .. 79 157 .. 0.88 2 ? 5.7 0.0 0.04 21 37 91 .. 222 275 .. 215 278 .. 0.89 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 3.7e-05 DUF5580 18 ssglldklqkelkildPissGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkg 72 s++ l ++qk + +ld sG + +ls+++l +++ + t+ l++rf +g FUN_000961-T1 86 SKQKLLHVQKKFSSLDTDNSGRITSEELSQVLLNNQIFILGKTLTTLVKRFEAEG 140 55667789*******************************************7654 PP == domain 2 score: 5.7 bits; conditional E-value: 0.04 DUF5580 37 sGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkgspelvnyeklllflkaaas 91 G++ +l +l rh++P+ + l+ rf g vn +++ fl +a+s FUN_000961-T1 222 NGLIDNKELKMLCKRHNLPISRSLLEKLVSRFDVDG-DGWVNLREFSKFLGKAVS 275 6999999*************************8665.568999999999999987 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.1 0.00084 0.44 180 248 .. 481 542 .. 470 574 .. 0.68 2 ? 5.1 0.1 0.036 19 157 238 .. 770 850 .. 716 870 .. 0.73 3 ? 2.6 0.0 0.2 1e+02 213 275 .. 892 953 .. 883 958 .. 0.84 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00084 Beta-prop_EIPR1 180 sglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkel 248 + ++l+D +kkk ++ +++v av+f+p + ++++t+g++ v+++++ +++++ + l FUN_000961-T1 481 HTITLWDWTRKKKLA----SARGNMDQVLAVNFSPFESHHFVTCGKQ-HVTFWELD--DNKLKQSRGRL 542 568899976666665....344557899*****************87.68999987..33444444444 PP == domain 2 score: 5.1 bits; conditional E-value: 0.036 Beta-prop_EIPR1 157 gg.eelrvaAldphdsslvlvace.sglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydg 238 + e+++ + p d + v++ c + +++++l + + v++ ++ ++v +d+++ + +l ++ +d +l++D +g FUN_000961-T1 770 EPpEKISEIQFSP-DGTHVALGCHdNDVYIYELLSEGRSVSLKVRCKAHTSSVSHLDWSKDGE-NLQSTSTDYELLFWDAL-QG 850 4445555555555.4455666676699999999988888888999999999999999987655.57788888999999865.44 PP == domain 3 score: 2.6 bits; conditional E-value: 0.2 Beta-prop_EIPR1 213 dpakknklltagdd.gvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssds 275 d++++++ll++gdd g v ++ Ry s +++ +k+h+ v +v+f + Li ++ d FUN_000961-T1 892 DRSHNKRLLATGDDfGNVNLY--RYPCVSEKAEPWIIKGHSAHVMNVRFLSDDTRLISVGGRDA 953 577888999999886788887..999999999******************99999998888775 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.1 9.6 5e+03 120 143 .. 399 422 .. 385 424 .. 0.79 2 ! 13.3 0.1 7.7e-05 0.04 82 171 .. 502 595 .. 461 618 .. 0.75 3 ? 4.8 0.0 0.029 15 74 155 .. 722 803 .. 643 819 .. 0.66 4 ! 6.7 0.0 0.0074 3.8 96 176 .. 786 870 .. 774 876 .. 0.75 5 ? -1.1 0.1 1.8 9.5e+02 123 156 .. 929 963 .. 925 964 .] 0.73 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 9.6 NBCH_WD40 120 irqhkdvvscvavtsdgsvlatGs 143 qh d + ++ v dg +a+G FUN_000961-T1 399 YTQHTDDIKSLCVHPDGVRIASGQ 422 578999999999999999999885 PP == domain 2 score: 13.3 bits; conditional E-value: 7.7e-05 NBCH_WD40 82 aqcfatlqtksen.fliscGnwensfqvislsdGrlvqs....irqhk.dvvscvavtsdgsvlatGsydttvmvwevlrarssekr.vrntqtel 170 q++a+ ++ e+ ++++cG+ + +f l+d +l qs ++h+ vsc+a +++ vl tG d ++ vw +++se vrn+++++ FUN_000961-T1 502 DQVLAVNFSPFEShHFVTCGKQHVTF--WELDDNKLKQSrgrlSKNHRpKYVSCIAFSVNCDVL-TGDTDGSICVWPEESNQISEELgVRNAHSDS 594 46666666665542689***988887..57888888887333224555368*********9987.8**********98887777654388887776 PP NBCH_WD40 171 s 171 FUN_000961-T1 595 V 595 4 PP == domain 3 score: 4.8 bits; conditional E-value: 0.029 NBCH_WD40 74 laenvelgaqcfatlqtksenfliscGnwensfqvislsdGrlvqsi.rqhkdvvscvavtsdgsvlatGsydttvmvwevlr 155 + n +lg+ + a+ + + l++ G + + ++ s G+l+ ++ ++ + +s ++ + dg+ +a G +d v ++e+l FUN_000961-T1 722 VWTNNKLGSEIQAAAFHPY-SSLVAVGFKKRGWALLNASTGELIIKLtSEPPEKISEIQFSPDGTHVALGCHDNDVYIYELLS 803 4456677777766665554.4588899999999999999999876651566789999********************999864 PP == domain 4 score: 6.7 bits; conditional E-value: 0.0074 NBCH_WD40 96 liscGnwensfqvis.lsdGrlvq...sirqhkdvvscvavtsdgsvlatGsydttvmvwevlrarssekrvrntqtelsrkdvv 176 ++ G +n + ls+Gr v + h vs + + dg+ l + s d ++ w++l++++ + + +te ++++v FUN_000961-T1 786 HVALGCHDNDVYIYElLSEGRSVSlkvRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDALQGEQITASASLRNTEWDTHNCV 870 5666777777777652578987753224578999999**************************9998887766666666555555 PP == domain 5 score: -1.1 bits; conditional E-value: 1.8 NBCH_WD40 123 hkdvvscva.vtsdgsvlatGsydttvmvwevlra 156 h v v ++ d ++++ G +d++ + w+++r FUN_000961-T1 929 HSAHVMNVRfLSDDTRLISVGGRDASTLQWKIVRI 963 5544444441566789999*************985 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.7 0.0 0.008 4.2 31 51 .. 97 117 .. 77 120 .. 0.88 2 ! 10.5 0.0 0.001 0.54 2 51 .. 222 270 .. 221 272 .. 0.84 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.008 EF-hand_8 31 frefDtDgdGkisfeeFcvll 51 f+ +DtD++G i+ ee+ ++l FUN_000961-T1 97 FSSLDTDNSGRITSEELSQVL 117 7779************99987 PP == domain 2 score: 10.5 bits; conditional E-value: 0.001 EF-hand_8 2 kgvItresLkrilalLglqd...lsedevdtlfrefDtDgdGkisfeeFcvll 51 +g I++ +Lk+ +++ +s + + l++ fD DgdG +++ eF +l FUN_000961-T1 222 NGLIDNKELKMLC----KRHnlpISRSLLEKLVSRFDVDGDGWVNLREFSKFL 270 5779999999944....444566**************************8776 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.1 3.8 2e+03 34 72 .. 386 423 .. 362 499 .. 0.65 2 ? -1.6 0.1 2.6 1.4e+03 79 124 .. 488 534 .. 406 577 .. 0.66 3 ? 0.5 0.0 0.62 3.2e+02 295 339 .. 703 748 .. 678 755 .. 0.71 4 ! 13.9 0.0 5.2e-05 0.027 13 82 .. 774 848 .. 765 878 .. 0.73 5 ? -3.0 0.0 6.9 3.6e+03 48 79 .. 926 958 .. 922 960 .. 0.81 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 3.8 Beta-prop_IFT122_1st 34 llvydtsdgtllqplkghkdtvycvayakdgkrfasgsa 72 +++yd + h d + ++ dg r+asg FUN_000961-T1 386 VVIYDEEL-HHQRHYTQHTDDIKSLCVHPDGVRIASGQV 423 44555432.233445567777777777777777777753 PP == domain 2 score: -1.6 bits; conditional E-value: 2.6 Beta-prop_IFT122_1st 79 wtsklegilkythndaiqcvsynpi.thqlascsssdfglwspeqks 124 wt k + d + +v++ p +h++ +c + +w +++ FUN_000961-T1 488 WTRKKKLASARGNMDQVLAVNFSPFeSHHFVTCGKQHVTFWELDDNK 534 45555555555566677777777763577777777777777655443 PP == domain 3 score: 0.5 bits; conditional E-value: 0.62 Beta-prop_IFT122_1st 295 llggsdkqvslftkdgvrlg.tvgeqnswvwtcqakpdsnyvvvgc 339 + ggsdk v l+ d r+ t + s + ++ +p s v vg FUN_000961-T1 703 VTGGSDKVVRLWHADQHRVVwTNNKLGSEIQAAAFHPYSSLVAVGF 748 5678888888888887776414445566666777777777777775 PP == domain 4 score: 13.9 bits; conditional E-value: 5.2e-05 Beta-prop_IFT122_1st 13 cindiafkpdgtqlilaag.srllvydt.sdg...tllqplkghkdtvycvayakdgkrfasgsadksviiwtsk 82 i +i f pdgt++ l + + + +y+ s+g +l k h +v + ++kdg+ + s s+d ++ w + FUN_000961-T1 774 KISEIQFSPDGTHVALGCHdNDVYIYELlSEGrsvSLKVRCKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDAL 848 5899**********9987515688998537773224566789******************************763 PP == domain 5 score: -3.0 bits; conditional E-value: 6.9 Beta-prop_IFT122_1st 48 lkghkdtvycvayakdgkrfas.gsadksviiw 79 +kgh v v + d r+ s g d s + w FUN_000961-T1 926 IKGHSAHVMNVRFLSDDTRLISvGGRDASTLQW 958 699999999999998888876547888888887 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.23 1.2e+02 73 114 .. 550 591 .. 528 599 .. 0.76 2 ! 12.3 0.0 0.00018 0.093 157 222 .. 773 836 .. 714 863 .. 0.82 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.23 Beta-prop_WDR35_TULP_N 73 avqvvaWNekykkLtssDenGliivWmlykgswveem.innrn 114 v+++a+ + Lt D++G i vW ++++ ee+ + n + FUN_000961-T1 550 YVSCIAFSVNCDVLT-GDTDGSICVWPEESNQISEELgVRNAH 591 577777777776665.7***************99998555554 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00018 Beta-prop_WDR35_TULP_N 157 lklakvewspdgklllfglkegevhvyd..segnflsklklkclekvekelkivgiewykgkeglvea 222 k++++++spdg ++ +g ++ +v +y+ seg +lk+ c ++++++ ++w k+ e+l+++ FUN_000961-T1 773 EKISEIQFSPDGTHVALGCHDNDVYIYEllSEGRS-VSLKVRCKA---HTSSVSHLDWSKDGENLQST 836 47999***********************5445554.457887764...45689999999887765544 PP >> Tricorn_2nd Tricorn protease second beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 9.2 4.8e+03 65 100 .. 385 420 .. 370 424 .. 0.79 2 ! 13.8 0.0 4.7e-05 0.024 13 120 .. 746 855 .. 715 875 .. 0.76 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 9.2 Tricorn_2nd 65 elvildadgsekaltdedlgrieelkvspdgkkiav 100 +vi+d + + ++ +++ i +l v pdg +ia FUN_000961-T1 385 VVVIYDEELHHQRHYTQHTDDIKSLCVHPDGVRIAS 420 578888888888888888888999999999988886 PP == domain 2 score: 13.8 bits; conditional E-value: 4.7e-05 Tricorn_2nd 13 ialtsRGkaFtvpawegpvlqlgeksgvryrlvewlndgkrvaavsdeeeeeelvildadgseka..ltdedlgrieelkvspdgkkiavannrne 106 +++ RG a + ++ +++l+++ + ++++++dg +va + +++ +l+ +s + +++++ +++l +s+dg+ + + e FUN_000961-T1 746 VGFKKRGWALLNASTGELIIKLTSEPPEKISEIQFSPDGTHVALGCHDNDVYIYELLSEGRSVSLkvRCKAHTSSVSHLDWSKDGENLQSTSTDYE 841 456789999999999999999999999999999999999999988776655433333333333324488999999999999999999999999999 PP Tricorn_2nd 107 Lllvdletgeatli 120 Ll d +ge+ + FUN_000961-T1 842 LLFWDALQGEQITA 855 99999777765544 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.66 3.5e+02 59 176 .. 549 666 .. 522 689 .. 0.67 2 ? 11.4 0.0 0.00038 0.2 61 177 .. 732 848 .. 715 870 .. 0.71 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.66 Beta-prop_NUP159_NUP214 59 prvihvaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlkarslv. 143 + v+ +aFs + + v++ +dg+++v es + ++e + + + s+ al + p++ ++ ++++ a k +l+ FUN_000961-T1 549 KYVSCIAFSVNCD--VLTGDTDGSICVWPEESNQ-ISEELGVRNAHS-DSVYALLVLPND---VVLSGGGGESIVRAWYKRPKLIp 627 3589999999998..8899999999999888877.445666666666.788888888883...22222222334444444555556 PP Beta-prop_NUP159_NUP214 144 .......svlkenvssfdwsnkgkqlvvgladgtaqqlkp 176 + ++v s+++ +g+ql++g d+++++ ++ FUN_000961-T1 628 tnvelklPREVSGVRSLAL-GTGNQLYIGTVDNHIWVASL 666 6666555555567777777.77778888888777777666 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00038 Beta-prop_NUP159_NUP214 61 vihvaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlkarslv... 143 + + aF+ +s lv++ ++ g a ++ ++ e +++ + ++i +++ p+ ++ +a+ + ++++++++l ++ + FUN_000961-T1 732 IQAAAFHPYSS-LVAVGFKKRGWALLNASTGE---LIIKLTSEP-PEKISEIQFSPD--GTHVALGCHDNDVYIYELLSEGRSvsl 810 55556666665.34434444444444444444...233333333.48899***9999..78***************9877666689 PP Beta-prop_NUP159_NUP214 144 ....svlkenvssfdwsnkgkqlvvgladgtaqqlkpa 177 + +++ vs +dws+ g++l ++d ++ + FUN_000961-T1 811 kvrcKAHTSSVSHLDWSKDGENLQSTSTDYELLFWDAL 848 9**********************999999988777664 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 2.2 1.1e+03 90 124 .. 432 466 .. 379 525 .. 0.65 2 ? 6.7 0.0 0.0077 4 113 163 .. 549 599 .. 538 619 .. 0.83 3 ? 1.4 0.0 0.32 1.6e+02 65 153 .. 770 861 .. 762 869 .. 0.78 4 ? 3.3 0.0 0.087 45 67 140 .. 885 960 .. 877 962 .. 0.76 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 2.2 Beta-prop_DCAF12 90 nslavyqlPtldPlclGdrkghkdwifaiawlsdt 124 + v++ +ld +c+ +d+ifa+a+ + + FUN_000961-T1 432 PHIRVWNSNSLDTICVIGVDYFEDAIFALAFSNKK 466 35677888888888888888888888888876654 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0077 Beta-prop_DCAF12 113 dwifaiawlsdtvavsGsrdgtlalwrvdpdklnasialkneaelpvyahi 163 +++++ia+ + +++G +dg++++w +++++++++ +n+++ vya + FUN_000961-T1 549 KYVSCIAFSVNCDVLTGDTDGSICVWPEESNQISEELGVRNAHSDSVYALL 599 5778899989999999*********************99999999999965 PP == domain 3 score: 1.4 bits; conditional E-value: 0.32 Beta-prop_DCAF12 65 qpasGihaielnpsktllatgGenpnslavyql.PtldPlclGdr.kghkdwifaiawlsdtvav.sGsrdgtlalwr.vdpdklnasialkn 153 +p+ i i++ p t +a g + n + +y+l + ++l r k+h+ ++ ++w +d + s s+d l +w ++ ++++as +l+n FUN_000961-T1 770 EPPEKISEIQFSPDGTHVALGCH-DNDVYIYELlSEGRSVSLKVRcKAHTSSVSHLDWSKDGENLqSTSTDYELLFWDaLQGEQITASASLRN 861 56677999999999999999876.577889987255679999988689***********99765438999*9999996356666666666555 PP == domain 4 score: 3.3 bits; conditional E-value: 0.087 Beta-prop_DCAF12 67 asGihaielnpsktllatgGenpnslavyqlPtldPlcl.Gdrkghkdwifaiawlsdt.vavs.Gsrdgtlalwrv 140 ++ +++++ k llatg + n + +y+ P + + kgh+ ++ + +lsd +s G rd++ w++ FUN_000961-T1 885 GTDVNSVDRSHNKRLLATGDDFGN-VNLYRYPCVSEKAEpWIIKGHSAHVMNVRFLSDDtRLISvGGRDASTLQWKI 960 567888999999*****9877665.799****986554413469************985234444888888778886 PP >> Ge1_WD40 WD40 region of Ge1, enhancer of mRNA-decapping protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.00014 0.074 170 218 .. 753 803 .. 740 817 .. 0.76 2 ? -2.0 0.0 3.5 1.8e+03 186 216 .. 817 847 .. 807 868 .. 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00014 Ge1_WD40 170 gkvqpaalkeGyieieeds..llveaalspdGtalatasadGlvkffqiyl 218 + + +a + e +i++ ++ +++e +spdGt +a ++d v + + FUN_000961-T1 753 WALLNASTGELIIKLTSEPpeKISEIQFSPDGTHVALGCHDNDVYIYELLS 803 5555555666666666655568**********************9998765 PP == domain 2 score: -2.0 bits; conditional E-value: 3.5 Ge1_WD40 186 edsllveaalspdGtalatasadGlvkffqi 216 ++s +++ s dG l +s+d ++ f+ FUN_000961-T1 817 HTSSVSHLDWSKDGENLQSTSTDYELLFWDA 847 5568999999**************9999975 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.23 1.2e+02 2 42 .. 504 544 .. 503 617 .. 0.61 2 ? 0.6 0.1 0.64 3.4e+02 14 45 .. 562 593 .. 550 726 .. 0.43 3 ? 6.2 0.0 0.013 6.6 9 108 .. 697 791 .. 689 801 .. 0.73 4 ? 4.9 0.0 0.033 17 1 39 [. 774 812 .. 774 838 .. 0.73 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.23 WDR90_beta-prop_4th 2 vnevvfspdes.hlatcsedGsvrvwslasmelvvqfqvlnq 42 v v fsp es h+ tc+++ v w l+ ++l l++ FUN_000961-T1 504 VLAVNFSPFEShHFVTCGKQ-HVTFWELDDNKLKQSRGRLSK 544 56688888776246788765.678888888777544444444 PP == domain 2 score: 0.6 bits; conditional E-value: 0.64 WDR90_beta-prop_4th 14 latcsedGsvrvwslasmelvvqfqvlnqscl 45 + t dGs+ vw +s+++ ++ v n FUN_000961-T1 562 VLTGDTDGSICVWPEESNQISEELGVRNAHSD 593 45666677777777776666555555554333 PP == domain 3 score: 6.2 bits; conditional E-value: 0.013 WDR90_beta-prop_4th 9 pdeshlatcsedGsvrvwslasmelvvqfqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelklhpha.valtaiay 97 p++ + t + d vr+w ++ +v + l + a+ p ss v+ G+ +++ s e+ +kl + + i++ FUN_000961-T1 697 PSSPTFVTGGSDKVVRLWHADQHRVVWTNNKLGSEIQAAAFHPYSSL------VAVGFKKRGWALLNASTGELIIKLTSEPpEKISEIQF 780 55667788888888888888888888888888888888888888776......7888888888888888888888887654146777888 PP WDR90_beta-prop_4th 98 sadGqtilsgd 108 s dG + g FUN_000961-T1 781 SPDGTHVALGC 791 88887665444 PP == domain 4 score: 4.9 bits; conditional E-value: 0.033 WDR90_beta-prop_4th 1 kvnevvfspdeshlatcsedGsvrvwslasmelvvqfqv 39 k++e+ fspd +h+a +d v ++ l s v ++v FUN_000961-T1 774 KISEIQFSPDGTHVALGCHDNDVYIYELLSEGRSVSLKV 812 688999*********999999999999877655555444 PP >> EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.018 9.6 32 66 .. 88 122 .. 71 133 .. 0.79 2 ? 2.3 0.0 0.57 3e+02 34 60 .. 243 269 .. 191 271 .. 0.85 3 ? 4.4 0.0 0.13 68 34 68 .. 243 277 .. 234 292 .. 0.80 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.018 EF-hand_FSTL1 32 syrellekyFkavDknkdkkldskEllelveknet 66 + ++k+F+++D+++ + + s+El +++ +n++ FUN_000961-T1 88 QKLLHVQKKFSSLDTDNSGRITSEELSQVLLNNQI 122 44446799********************9988876 PP == domain 2 score: 2.3 bits; conditional E-value: 0.57 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllel 60 r+llek +++D + d+ ++ E+ ++ FUN_000961-T1 243 RSLLEKLVSRFDVDGDGWVNLREFSKF 269 567788888889999999998888877 PP == domain 3 score: 4.4 bits; conditional E-value: 0.13 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllelveknetva 68 r+llek +++D + d+ ++ E+ +++ k +va FUN_000961-T1 243 RSLLEKLVSRFDVDGDGWVNLREFSKFLGKAVSVA 277 56888999999*************99998655554 PP >> Beta-prop_Vps41 Vps42 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.058 30 37 77 .. 385 425 .. 382 427 .. 0.93 2 ? 5.2 0.0 0.03 16 55 103 .. 772 821 .. 741 831 .. 0.78 3 ? 5.1 0.0 0.032 16 27 76 .. 785 839 .. 772 855 .. 0.54 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.058 Beta-prop_Vps41 37 iihildpdgntirtfkahrasisslsidtdGeylAsaSmDG 77 +++i+d + + r+++ h+ i+sl ++ dG +As+ + G FUN_000961-T1 385 VVVIYDEELHHQRHYTQHTDDIKSLCVHPDGVRIASGQVKG 425 6899********************************98776 PP == domain 2 score: 5.2 bits; conditional E-value: 0.03 Beta-prop_Vps41 55 rasisslsidtdGeylAsaSmDGtvvigslseeeei.avdFkrpvkaval 103 +is+++ + dG+++A + D v i+ l +e ++ + + +++ ++ ++ FUN_000961-T1 772 PEKISEIQFSPDGTHVALGCHDNDVYIYELLSEGRSvSLKVRCKAHTSSV 821 579**************************998877514477777776665 PP == domain 3 score: 5.1 bits; conditional E-value: 0.032 Beta-prop_Vps41 27 kvlvfgthsGiihildp.....dgntirtfkahrasisslsidtdGeylAsaSmD 76 +++++g h ++i++ + + + kah++s+s+l ++dGe l s S D FUN_000961-T1 785 THVALGCHDNDVYIYELlsegrSVSLKVRCKAHTSSVSHLDWSKDGENLQSTSTD 839 3455555555555554311111223334555666666666666666666666666 PP >> SPEF2_C SPEF2 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.00087 0.45 88 119 .. 86 117 .. 77 119 .. 0.90 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00087 SPEF2_C 88 sqeeLLetlkrfkevDeestglitreqylqve 119 s+++LL+++k+f ++D++++g it+e+ +qv FUN_000961-T1 86 SKQKLLHVQKKFSSLDTDNSGRITSEELSQVL 117 7899**********************999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (964 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 697 (0.0272852); expected 510.9 (0.02) Passed Vit filter: 92 (0.00360149); expected 25.5 (0.001) Passed Fwd filter: 49 (0.00191818); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 49 [number of targets reported over threshold] # CPU time: 0.60u 0.39s 00:00:00.99 Elapsed: 00:00:00.47 # Mc/sec: 8333.70 // Query: FUN_000962-T1 [L=536] Description: FUN_000962 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-14 53.6 9.7 2.2e-14 53.6 9.7 2.4 3 Ion_trans_2 Ion channel 3.2e-10 40.1 2.7 3.2e-10 40.1 2.7 1.5 2 Ion_trans Ion transport protein 2.6e-06 27.8 3.2 6e-06 26.6 3.2 1.8 1 Lig_chan Ligand-gated ion channel Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -7.5 3.9 3 2.6e+04 31 38 .. 12 19 .. 4 19 .. 0.54 2 ! 53.6 9.7 2.6e-18 2.2e-14 5 77 .. 215 287 .. 191 289 .. 0.86 3 ? -1.5 0.2 0.4 3.4e+03 49 70 .. 433 454 .. 427 458 .. 0.77 Alignments for each domain: == domain 1 score: -7.5 bits; conditional E-value: 3 Ion_trans_2 31 fsvvtltT 38 +++tltT FUN_000962-T1 12 LCTTTLTT 19 35555555 PP == domain 2 score: 53.6 bits; conditional E-value: 2.6e-18 Ion_trans_2 5 lvlifgtviyll..eegwegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllflavlgevl 77 ++l+ + ++ + +e++ ++d++++++vt+tTvGYGd +P++ gr+f++++i++Gi l+++f+a ++ + FUN_000962-T1 215 VWLLESLFFSKEfsGEFY--HGVWDGFWWAFVTMTTVGYGDRSPKSIPGRIFCFFWIITGINLIAIFTALVTATV 287 555555555555666664..699**********************************************998876 PP == domain 3 score: -1.5 bits; conditional E-value: 0.4 Ion_trans_2 49 dagrlftivyiliGiplfllfl 70 + r++ti +++G ++f+ ++ FUN_000962-T1 433 LFNRVITIGGGVVGSLMFIGLV 454 5678999999999988887665 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.3 0.62 5.3e+03 4 27 .. 2 25 .. 1 34 [. 0.73 2 ! 40.1 2.7 3.8e-14 3.2e-10 97 238 .. 165 290 .. 143 293 .. 0.69 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 0.62 Ion_trans 4 felfilllillntvvlaletyfqp 27 +++++++ ++l t++l+ + f + FUN_000962-T1 2 WHITVTIYTILCTTTLTTHALFLS 25 788888888888888888777766 PP == domain 2 score: 40.1 bits; conditional E-value: 3.8e-14 Ion_trans 97 vlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlf..ggklkkeekewenpdngrtnFdnfgnallwlfqtltte 190 +++++ + r++ l+ ++ +t +sl+++ +++ + +l+++l++ a+ g+++ + ++ +++ + ++ +++ ++w+f+t+tt+ FUN_000962-T1 165 FVKVVSAPRVMLLVYDGPK-QTRTQSLVNT---IFYAWPFLIFILVAAASSGLSVWllESLFF-------SKEFSGEFYHGVWDGFWWAFVTMTTV 249 5666666677777766666.3334444444...444444444444444444433330023333.......34444556889*************** PP Ion_trans 191 gwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqel 238 g+gd ++ + ++ +f++f i+ g+ l++++ a+++ ++ FUN_000962-T1 250 GYGDRSPKSIPGR-------IFCFFWIITGINLIAIFTALVTATVTAT 290 *************.......*********************9988665 PP >> Lig_chan Ligand-gated ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 3.2 7e-10 6e-06 6 98 .. 202 291 .. 196 430 .. 0.82 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 7e-10 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Lig_chan 6 llilvalllvavvlfllerl.spyewrepeeeeeneftlsnslwfvlgalvqqg.aeekpkslsaRivvavWwffvlillssYtAnLaafltver 98 ++ilva ++ ++lle l +e++++ + +++ +w ++ +++ g ++ +pks+ +Ri ++W++ + l++ +tA +a++t + FUN_000962-T1 202 IFILVAAASSGLSVWLLESLfFSKEFSGE-----FYHGVWDGFWWAFVTMTTVGyGDRSPKSIPGRIFCFFWIITGINLIAIFTALVTATVTATT 291 56788888899999999985156667776.....8899***************************************************998764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (536 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1312 (0.0513603); expected 510.9 (0.02) Passed bias filter: 946 (0.0370327); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 5178.74 // Query: FUN_000964-T1 [L=461] Description: FUN_000964 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-42 145.7 21.6 4.1e-38 131.7 13.1 2.0 2 MFS_1 Major Facilitator Superfamily Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 131.7 13.1 1.6e-42 4.1e-38 9 318 .. 54 369 .. 44 379 .. 0.80 2 ! 26.8 8.4 1.3e-10 3.3e-06 71 170 .. 330 433 .. 327 457 .. 0.81 Alignments for each domain: == domain 1 score: 131.7 bits; conditional E-value: 1.6e-42 MFS_1 9 algrsl.lgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrfGrrrvlllglllfalglllll..fasslw.lllvlrvlqGlgag 100 +g+s+ +g+++p l +++ ++++ ++ +l++ + l+ ++ + l dr+G r + ++g l+ +lg lll+ +s++ + l v+ G+g++ FUN_000964-T1 54 LMGYSCsFGVLFP-PLLDHFKQDSATTAWVGSLYLSISTLLGPVSANLCDRYGCRVTAFFGGLTCVLG-LLLTsqA-PSIFcMYLTYSVIVGFGTC 146 3444444677777.899***************************************************.7777333.******************* PP MFS_1 101 alfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfgwravFlilailallaavlaalllprpppeskrkkpaee......... 187 ++++a+ +++ ++f k +r++a+g+ls g+++G++++ +l l+++++gwr +F+++a++a + +++ +l++++++ + ++ee FUN_000964-T1 147 CVYTASFVVVPRYFIK-RRAQATGILSCGTSVGSLVMGPLLQLFLDSIGWRNTFIAMAGIASVTCLI--ALIYDSRTANQILVNEEEvnfeaqtmv 239 **************99.*****************999999999999******************998..999999999999999999666666665 PP MFS_1 188 ...apapllpawkallrdpvlwlllalllf.glaffa..lltllplyqevlglsglllaglllglaallgaigrlllgrlsdr..lgrrrrlllal 275 +++ + ++++l+++ l ++++++++ +l+ + +ll +y+e++g++ + +++++ ++l++ ++r+ ++r+ d +++++++ al FUN_000964-T1 240 iakKQSTW---FEDILKNRDLVTWTVCCGVlFLG--LynPQVLLITYAEERGIP-ADKSAMFFCYMGLASTVSRICVSRICDSqcINAQTIIQGAL 329 54444444...44888888883333333331223..2459999999********.566666777777777777********998888888888888 PP MFS_1 276 lllllaalgllllsltesslwlllallllGfgfglvfplllal 318 l++ +a+ +l ++s ++++++ l++Gf+ g++ ++++ FUN_000964-T1 330 LSISAATGLLPFASAY--YHIMVY-ALVFGFCDGCFGGCINFQ 369 8888888888888877..555544.344577777777766654 PP == domain 2 score: 26.8 bits; conditional E-value: 1.3e-10 MFS_1 71 lfalglllll.fasslwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllgglla.slfgwravFlilailalla 164 l++ +++ ll fas ++ ++v ++ G++ g++ +++ + + + ++a+g++++ ++ + a Gp+++g++a ++ +F+++a++ ++a FUN_000964-T1 330 LSISAATGLLpFASAYYHIMVYALVFGFCDGCFGGCINFQVIGCVQSHCTSKAFGFWMGVTSPSLAAGPPIAGYVAdKMKSYGPAFYVSAAFVFVA 425 333334555567556669**********************************************************77888*************** PP MFS_1 165 av..laal 170 av ++++ FUN_000964-T1 426 AVipCVLC 433 *9554434 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (461 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 897 (0.0351145); expected 510.9 (0.02) Passed bias filter: 455 (0.0178117); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4500.63 // Query: FUN_000965-T1 [L=846] Description: FUN_000965 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-07 29.7 0.4 2.1e-06 27.9 0.0 2.1 2 NT-C2 N-terminal C2 in EEIG1 and EHBP1 proteins 2e-06 28.4 11.6 4.8e-06 27.1 11.6 1.6 1 bMERB_dom Bivalent Mical/EHBP Rab binding domain ------ inclusion threshold ------ 0.095 13.6 0.0 0.25 12.3 0.0 1.6 1 PNMA_N PNMA N-terminal RRM-like domain Domain annotation for each model (and alignments): >> NT-C2 N-terminal C2 in EEIG1 and EHBP1 proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.9 0.0 2.5e-10 2.1e-06 46 121 .. 25 103 .. 10 121 .. 0.85 2 ? -3.2 0.1 1 8.6e+03 7 22 .. 732 748 .. 730 753 .. 0.78 Alignments for each domain: == domain 1 score: 27.9 bits; conditional E-value: 2.5e-10 NT-C2 46 lvkngrakfn..eelsipvtlfld.kkgkkyeeKllelsvykvtkkgkkkvlGkvslDLaeyanlkkkpttvslllkks 121 + +g++++ +++++++t+f++ ++ + y++ ++ +++ ++tk g kkv++ s+DL +y+++kkk+ + l FUN_000965-T1 25 NPLRGIHVWPepDPVTLTTTMFKNpEREGVYQDHKWGIQIKNETKNGCKKVIAIGSFDLDNYISEKKKSFEIKVTLIPT 103 56788999998899**********988889**************999999**************998888877777666 PP == domain 2 score: -3.2 bits; conditional E-value: 1 NT-C2 7 fqfelkihelqnlpl.e 22 f+++ +ih+l+n+ + + FUN_000965-T1 732 FSLNQEIHALSNVISkV 748 89999******998754 PP >> bMERB_dom Bivalent Mical/EHBP Rab binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 11.6 5.7e-10 4.8e-06 7 110 .. 733 838 .. 727 844 .. 0.87 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 5.7e-10 bMERB_dom 7 eieeeqkeleergvelEkkLR..eesesgeeeeeelleewfeLvneknaLvrreseLmilakeqeLeeeqaeleqelrellekedkekteedkkre 100 +++e+ +l + ++E++L ++ ++ +ee + l ++w++L + ++L r ++L +l+ +++L ++ l+ el+ l+e+ed++k+++++++e FUN_000965-T1 733 SLNQEIHALSNVISKVENELQktMKFAECHEECSGLKQDWLSLNKYMDELNTRKQNLELLKLTENLKQCVGLLRAELKLLFEMEDWRKSNRQRAQE 828 6788899999999999999996544445555556699*********************************************************** PP bMERB_dom 101 eelleelvei 110 + ll+ ++++ FUN_000965-T1 829 TTLLNLVLSL 838 ****988876 PP >> PNMA_N PNMA N-terminal RRM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 2.9e-05 0.25 15 50 .. 114 149 .. 109 160 .. 0.85 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.9e-05 PNMA_N 15 vdarkalLilgiPedceeaeieetlkaalkplgeyr 50 + +L+ g+P +e+e++e l++a+++l++ + FUN_000965-T1 114 FQLTSVMLVDGVPYGSKEEELKEYLRDAIQSLSSLK 149 5566789*************************9866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (846 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1891 (0.0740262); expected 510.9 (0.02) Passed bias filter: 623 (0.0243883); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.38s 00:00:00.79 Elapsed: 00:00:00.41 # Mc/sec: 8251.43 // Query: FUN_000965-T2 [L=802] Description: FUN_000965 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-06 28.5 11.6 4.5e-06 27.2 11.6 1.7 1 bMERB_dom Bivalent Mical/EHBP Rab binding domain ------ inclusion threshold ------ 0.011 15.9 0.4 0.011 15.9 0.4 2.2 3 NT-C2 N-terminal C2 in EEIG1 and EHBP1 proteins 0.088 13.7 0.0 0.23 12.4 0.0 1.6 1 PNMA_N PNMA N-terminal RRM-like domain Domain annotation for each model (and alignments): >> bMERB_dom Bivalent Mical/EHBP Rab binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 11.6 5.3e-10 4.5e-06 7 110 .. 689 794 .. 683 800 .. 0.87 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 5.3e-10 bMERB_dom 7 eieeeqkeleergvelEkkLR..eesesgeeeeeelleewfeLvneknaLvrreseLmilakeqeLeeeqaeleqelrellekedkekteedkkre 100 +++e+ +l + ++E++L ++ ++ +ee + l ++w++L + ++L r ++L +l+ +++L ++ l+ el+ l+e+ed++k+++++++e FUN_000965-T2 689 SLNQEIHALSNVISKVENELQktMKFAECHEECSGLKQDWLSLNKYMDELNTRKQNLELLKLTENLKQCVGLLRAELKLLFEMEDWRKSNRQRAQE 784 6788899999999999999996544445555556699*********************************************************** PP bMERB_dom 101 eelleelvei 110 + ll+ ++++ FUN_000965-T2 785 TTLLNLVLSL 794 ****988876 PP >> NT-C2 N-terminal C2 in EEIG1 and EHBP1 proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 0.4 1.3e-06 0.011 64 121 .. 1 59 [. 1 77 [. 0.84 2 ? -4.3 0.3 2.2 1.9e+04 110 127 .. 197 214 .. 192 227 .. 0.56 3 ? -3.1 0.1 0.95 8.1e+03 7 22 .. 688 704 .. 686 709 .. 0.78 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 1.3e-06 NT-C2 64 lfld.kkgkkyeeKllelsvykvtkkgkkkvlGkvslDLaeyanlkkkpttvslllkks 121 +f++ ++ + y++ ++ +++ ++tk g kkv++ s+DL +y+++kkk+ + l FUN_000965-T2 1 MFKNpEREGVYQDHKWGIQIKNETKNGCKKVIAIGSFDLDNYISEKKKSFEIKVTLIPT 59 6778777889**************999999**************998888877777666 PP == domain 2 score: -4.3 bits; conditional E-value: 2.2 NT-C2 110 kpttvslllkkskkknat 127 k++++ + +k +k+n++ FUN_000965-T2 197 KSQHRCKKQQKECKDNSI 214 444555555555555543 PP == domain 3 score: -3.1 bits; conditional E-value: 0.95 NT-C2 7 fqfelkihelqnlpl.e 22 f+++ +ih+l+n+ + + FUN_000965-T2 688 FSLNQEIHALSNVISkV 704 89999******998754 PP >> PNMA_N PNMA N-terminal RRM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 2.7e-05 0.23 15 50 .. 70 105 .. 65 116 .. 0.85 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.7e-05 PNMA_N 15 vdarkalLilgiPedceeaeieetlkaalkplgeyr 50 + +L+ g+P +e+e++e l++a+++l++ + FUN_000965-T2 70 FQLTSVMLVDGVPYGSKEEELKEYLRDAIQSLSSLK 105 5566789*************************9866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (802 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1797 (0.0703464); expected 510.9 (0.02) Passed bias filter: 562 (0.0220004); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 7778.81 // Query: FUN_000966-T1 [L=127] Description: FUN_000966 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (127 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 722 (0.0282638); expected 510.9 (0.02) Passed bias filter: 494 (0.0193384); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1284.36 // Query: FUN_000967-T1 [L=173] Description: FUN_000967 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (173 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 553 (0.0216481); expected 510.9 (0.02) Passed bias filter: 446 (0.0174594); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1741.62 // Query: FUN_000968-T1 [L=424] Description: FUN_000968 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-87 295.5 0.0 1.3e-87 295.1 0.0 1.1 1 An_peroxidase Animal haem peroxidase Domain annotation for each model (and alignments): >> An_peroxidase Animal haem peroxidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 295.1 0.0 4.9e-92 1.3e-87 143 522 .. 2 398 .. 1 405 [. 0.84 Alignments for each domain: == domain 1 score: 295.1 bits; conditional E-value: 4.9e-92 An_peroxidase 143 preqlnqvTsflDasqvYGsseeearkLRsfsgGkLkvekskegkellpldedkkeeckseeeekkcflaGdsranenpgltalhtlflReHNriA 238 p++ n+vT+++D+sq+YGs++ ++kLRsf++Gk+kve e ++llplde++ +++ ++G +r n+++gl+++h +f+ReHN+i+ FUN_000968-T1 2 PNTFQNDVTHWWDGSQLYGSNDLMNAKLRSFREGKMKVE---E-DGLLPLDENT---------GIE--ITGFNR-NWWIGLSLMHNIFTREHNAIC 81 56788********************************95...3.79****7766.........344..679888.********************* PP An_peroxidase 239 deLkklnphwsdeklyqeARkiviAliqhItynewLpaiLgkeamekygllpk.............gy.........kgYdp.........nvdps 303 d+Lk +p+wsd++ly++AR +++A+iq+I+ ew+paiL++ ++ + gl+++ + + +p nv+ s FUN_000968-T1 82 DMLKGYYPEWSDQQLYDKARLVNVAVIQKIHSVEWTPAILNN-TALRAGLRLNfglspgkevidwlEAhnisadvsgEILKPivgqpseffNVPFS 176 *****************************************7.444556666554444444443330023333333311222555557789***** PP An_peroxidase 304 isnefatAafrfghslippklelld.e.kkveeeeslrlsdsffnpe.rlle.ggidellrgllsqpaeav.denvteeltn.klfeke.kesglD 392 +++ef++ ++r+ h l+p++l++ + + ++ ++++l + f+ + ++l+ + +++++ ++ ++++a +n++++l+n kl +++ k +D FUN_000968-T1 177 LTEEFVS-VYRM-HPLLPDDLHIGSfAiGQ-STGKTYSLLEYSFSGArKVLKeNRLEDIVFTFGVEHPGALtLHNYPKNLRNlKLPSHQqKGETID 269 *****98.****.*********99964333.234567777777766656666478**************999**********666555568899** PP An_peroxidase 393 laalniqRgRDhGlpsYnefRelcglkkaksfedltdeiseeeleklkelY.ksvddiDllvGgllEkplpgg..lvgptfaciiaeqfrrlrdgD 485 la+++i R+R++Glp+Yn+fR+l +l+++ksfe+lt+ ++e+ + lke+Y ++++++Dll+G+l+E+p p+g + +++f++++a+++rrl+ D FUN_000968-T1 270 LATIDILRDRERGLPRYNNFRRLTNLRPVKSFENLTS--NREHSDLLKEIYnDDIEKLDLLIGCLAEEPRPDGfgFGETAFNIFVAMASRRLQ-TD 362 ************************************9..9999999*****99*******************96556889************9.** PP An_peroxidase 486 RFwyengnqpgvFteeqleeirktslarvlcdntdei 522 RF ++++++ ++t+e+l++i+ t +++vl + +++i FUN_000968-T1 363 RFMTDDYTS-DIYTPEGLKWIQDTDMRSVLKRAFPDI 398 *****9888.9********************998875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (424 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 599 (0.0234488); expected 510.9 (0.02) Passed bias filter: 581 (0.0227442); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4292.18 // Query: FUN_000969-T1 [L=134] Description: FUN_000969 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-19 70.5 0.1 1.7e-19 70.3 0.1 1.0 1 An_peroxidase Animal haem peroxidase Domain annotation for each model (and alignments): >> An_peroxidase Animal haem peroxidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.3 0.1 6.6e-24 1.7e-19 2 140 .. 5 123 .. 4 132 .. 0.84 Alignments for each domain: == domain 1 score: 70.3 bits; conditional E-value: 6.6e-24 An_peroxidase 2 rtidGscNnlknpewGaagtpfaRllpaeYedgvseprgstgkelPsarevsnkllaedestpdskltlllmqwgqfidhDltstpestskseeie 97 r++dG+cN+l++p G+ +f+R+++++ ++ Ps+re+s++lla+d+++p ++l+ll++ w+qf hD++++ FUN_000969-T1 5 RSHDGTCNDLDQPASGSRFYRFGRNVNRTK--TFEDKDL----LKPSPREISRRLLARDKFIPVKQLNLLAAGWIQFNLHDWFDHGPPD------- 87 9*************************8772..2222222....34****************************************9999....... PP An_peroxidase 98 ccaspekhpeCfpIeipknDpvfsktgkkclpfvRssrpdckl 140 + ++ ++I++ ++Dp ++k+ + +++ R++r +c++ FUN_000969-T1 88 -VR-SRR----IKIDLDQDDPDYEKY-SGKMKIPRTKRDGCQK 123 .22.344....89**********774.5799999997888886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 308 (0.0120572); expected 510.9 (0.02) Passed bias filter: 283 (0.0110785); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1328.03 // Query: FUN_000970-T1 [L=163] Description: FUN_000970 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-09 37.1 9.0 6e-09 36.5 9.0 1.3 1 WSC WSC domain ------ inclusion threshold ------ 0.1 13.1 2.1 0.15 12.5 2.1 1.3 1 Fer2_3 2Fe-2S iron-sulfur cluster binding domain 0.21 12.2 1.1 0.39 11.3 1.1 1.4 1 Baculo_8kDa Baculoviridae 8.2 KDa protein Domain annotation for each model (and alignments): >> WSC WSC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 9.0 7e-13 6e-09 2 70 .. 73 137 .. 72 149 .. 0.85 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 7e-13 WSC 2 lGCysdssessrlllassasssdmtvekCvaaCkekgykyagleygkeCyCgnslpssskkaeeseCnt 70 lGC+ + + ++ ++ + ++ +tv++Cv++Ck+ +y+ya++e+ ++C+Cg+++ +++ s C+ FUN_000970-T1 73 LGCFAVK---KCSSFPYLYAKRGLTVGQCVQHCKNLNYPYAAIEQCRKCFCGENVMTYAQTPRRS-CKK 137 6999955...7899999***************************************998888666.873 PP >> Fer2_3 2Fe-2S iron-sulfur cluster binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 2.1 1.8e-05 0.15 33 81 .. 97 144 .. 79 162 .. 0.74 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.8e-05 Fer2_3 33 daLqkikeeldeslafrasCregvCGscamkinGkpklaCktkiedlke 81 +++q+ k+ + + a ++Cr+ CG+ m++ +p+ +Ck++ ++ k FUN_000970-T1 97 QCVQHCKNL-NYPYAAIEQCRKCFCGENVMTYAQTPRRSCKKQRRRSKC 144 555555544.455666689**********************99887654 PP >> Baculo_8kDa Baculoviridae 8.2 KDa protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 1.1 4.6e-05 0.39 29 60 .. 107 138 .. 100 143 .. 0.82 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 4.6e-05 Baculo_8kDa 29 etYesviqiRklmckeneitpsekdlkfkkkd 60 Y + q+Rk +c en +t ++ ++++kk+ FUN_000970-T1 107 YPYAAIEQCRKCFCGENVMTYAQTPRRSCKKQ 138 5699**************99999988888865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (163 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1080 (0.0422783); expected 510.9 (0.02) Passed bias filter: 508 (0.0198865); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1639.59 // Query: FUN_000971-T1 [L=707] Description: FUN_000971 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-107 360.9 0.0 2e-107 360.5 0.0 1.1 1 An_peroxidase Animal haem peroxidase 3.4e-12 46.9 13.3 5.8e-12 46.2 13.3 1.4 1 WSC WSC domain Domain annotation for each model (and alignments): >> An_peroxidase Animal haem peroxidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 360.5 0.0 1.6e-111 2e-107 1 524 [. 168 689 .. 168 696 .. 0.85 Alignments for each domain: == domain 1 score: 360.5 bits; conditional E-value: 1.6e-111 An_peroxidase 1 yrtidGscNnlknpewGaagtpfaRllpaeYedgvseprgstgkelPsarevsnkllaedestpdskltlllmqwgqfidhDltstpestskseei 96 +rtidGscN+l+n+ G+ +f+R++p +Y+ s+p+ P++r v +kll+++++ + + l+l++++w qf++hD++++ + FUN_000971-T1 168 MRTIDGSCNDLNNTAAGSRFYRFGRNVPLQYAY--SKPQD---LLKPDPRVVARKLLQRKKFLEVPWLNLFAVAWVQFMAHDWFDHGTPV------ 252 59*****************************87..88888...345************9999998***********************99...... PP An_peroxidase 97 eccaspekhpeCfpIeipknDpvfsktgkkclpfvRssrpdckl.g..npreqlnqvTsflDasqvYGsseeearkLRsfsgGkLkvekskegkel 189 e ++I+++k+Dp+ ++ + ++++ R++ +c+ g p n+vT+++D+sq+YGs+e + +++Rsf +GkLkv+ + +++ FUN_000971-T1 253 -----REM---PIKIQLEKKDPLKKR-LRGVMKVDRTKPDKCRVkGdsVPPAYQNDVTHWWDGSQLYGSDEYTHARVRSFVDGKLKVD---D-DGF 335 .....333...389*********965.567******9666799966999*************************************94...4.69* PP An_peroxidase 190 lpldedkkeeckseeeekkcflaGdsranenpgltalhtlflReHNriAdeLkklnphwsdeklyqeARkiviAliqhItynewLpaiLgk..... 280 lpld+++ +++ ++G ++ n+++gl++lh lf+ReHN+i+d+L++ +p+w d+kl+q+AR i+ A+i +I++ ew+ aiL++ FUN_000971-T1 336 LPLDPKT---------KIE--ISGFTK-NWWVGLSLLHNLFTREHNAICDMLRQKHPSWMDDKLFQTARLINTAQIVQIHTLEWTGAILNTdfihe 419 ***7666.........233..567655.***************************************************************66666 PP An_peroxidase 281 .eamekygllpk...............gy........kgYdpnvdpsisnefatAafrfghslippklelld..ekkveeeeslrlsdsffnpe.r 349 + +++g+l k g +Y + v+ s+++ef++ ++r+ hsl+p+ ++l+ ++k + ++++l + f ++ + FUN_000971-T1 420 sQIGQWNGTLSKkvkdilkkmnvtlgkGSipthrgnlPDY-RGVPFSLTEEFVS-VYRM-HSLLPDIISLRCmgKDKL-NGRTYSLPNFSFGEArK 511 5222444444444544444333333331134443333445.49*********98.****.********9999644454.5569***9998888766 PP An_peroxidase 350 lle.ggidellrgllsqpaeav.denvteeltn.klfeke..kesglDlaalniqRgRDhGlpsYnefRelcglkkaksfedltdeiseeeleklk 440 +++ +++ ++l+ ++ +a++ +n+++ l + k+ +++ ++ +Dla+++i R+R++G+p+Yn+fR+l++l+++++fe+lt+ ++ ++++l+ FUN_000971-T1 512 MFDeNDLGDILYTFGVGKAGQLvLHNYPTTLMElKIPKSQtgRPAPIDLATIDILRDRERGIPRYNQFRRLLNLTAPSTFEELTN--DTVTAAELR 605 666468********99999888899999999984555555788899**************************************9..8899999** PP An_peroxidase 441 elY.ksvddiDllvGgllEkplpgg.lvgptfaciiaeqfrrlrdgDRFwyengnqpgvFteeqleeirktslarvlcdntdeiee 524 ++Y ++++d+Dll+G l+E + +g + g+ f+ ++ ++ rrl DRF + ++++ + +t+e+l+++++++++rvl +n+ + + FUN_000971-T1 606 DAYkNQIEDVDLLIGSLAEARPEGFgFGGTPFHLFLCMANRRLN-TDRFLTIDYKE-EYYTKEGLQWVERSTFKRVLLRNFANVKG 689 ***99**************888887567999************9.*******9888.9**********************998775 PP >> WSC WSC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 13.3 4.5e-16 5.8e-12 1 82 [] 70 149 .. 70 149 .. 0.92 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 4.5e-16 WSC 1 ylGCysdssessrlllassasssdmtvekCvaaCkekgykyagleygkeCyCgnslpssskkaeeseCntsCsGdsselCGg 82 y+GC+s s s+ + + + + ++t+++C+a+Ck++ ++ya+l +g+ CyCg ++ ++ ++e + C +C+G++++ CGg FUN_000971-T1 70 YIGCFSAS-LISDYKFQMQHLTPSVTPDNCIAQCKTAMFSYAALGQGQRCYCGVGYETKKYADECN-CRKKCKGNKKNRCGG 149 99****88.577777788888999**********************************99888766.**************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (707 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 641 (0.025093); expected 510.9 (0.02) Passed bias filter: 440 (0.0172245); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 6679.24 // Query: FUN_000972-T1 [L=465] Description: FUN_000972 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-26 91.5 0.2 6.8e-26 90.5 0.2 1.6 1 PUB PUB domain 5.8e-09 36.5 0.0 1.7e-08 35.0 0.0 1.8 1 UBX UBX domain ------ inclusion threshold ------ 0.024 15.1 0.7 0.075 13.5 0.7 1.9 1 DUF4110 Domain of unknown function (DUF4110) Domain annotation for each model (and alignments): >> PUB PUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.5 0.2 7.9e-30 6.8e-26 2 81 .. 196 279 .. 195 280 .. 0.93 Alignments for each domain: == domain 1 score: 90.5 bits; conditional E-value: 7.9e-30 PUB 2 eklkealetLlkyleNilsnpneekyRkirlsNkafqekvlplegalelLeaiGFeekve....eeeeflvleeesleqlkklr 81 +k+k ++++L++yl+Ni++np+eek++ki++sNk+fqe+v+p++ga+++L+a+GFe kv ee ++v+++e++ +++ l+ FUN_000972-T1 196 NKIKACVDLLCRYLDNICKNPDEEKFQKIKKSNKVFQERVAPIRGAVQFLLACGFEDKVIsvegLEENYFVMPKEKCSDCESLE 279 799******************************************************999998766779999999999988775 PP >> UBX UBX domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.0 0.0 2e-12 1.7e-08 7 79 .. 361 429 .. 357 432 .. 0.90 Alignments for each domain: == domain 1 score: 35.0 bits; conditional E-value: 2e-12 UBX 7 trlqiRlpdGsrlvrrFnssdklqsvydfvdskrydeeepfsLltsfPrreltkedekktLkelgllpssalv 79 t +++R+pdG l+ +F s++k+++v++fv++ ++ + +pf+L + +l++e+ +L +lgl+p +++ FUN_000972-T1 361 TLIRVRFPDGFILQGTFYSREKVRDVVEFVRQSLVSDWQPFQLFETT--GQLKDEN--ASLIDLGLVPAAVVN 429 679****************************************7764..6788887..9*****999999885 PP >> DUF4110 Domain of unknown function (DUF4110) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.7 8.8e-06 0.075 8 59 .. 306 353 .. 299 358 .. 0.87 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 8.8e-06 DUF4110 8 ptPrpfEslrdFfaRtsaeWqelaieslkekgsekksgKeLkkeafelAeer 59 ++ fE dFf++ts+e ++ i++ +e ++ +Lk++a++ Ae+r FUN_000972-T1 306 NQASHFEVPSDFFSKTSEEIKRAQISRSEEV----ERSCQLKTRAMREAEKR 353 55678*********************99975....78899*******99998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (465 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1202 (0.0470542); expected 510.9 (0.02) Passed bias filter: 689 (0.026972); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 4545.34 // Query: FUN_000973-T1 [L=313] Description: FUN_000973 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-12 46.1 3.3 4.7e-11 42.9 3.3 2.1 1 PIH1 PIH1 N-terminal domain 9.2e-09 36.2 0.2 3.7e-08 34.3 0.1 1.9 2 PIH1_CS PIH1 CS-like domain ------ inclusion threshold ------ 0.017 15.8 0.4 0.028 15.1 0.4 1.3 1 eIF3g Eukaryotic translation initiation factor 3 subunit 0.22 12.1 0.0 0.37 11.4 0.0 1.3 1 DUF6912 Family of unknown function (DUF6912) Domain annotation for each model (and alignments): >> PIH1 PIH1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.9 3.3 7.4e-15 4.7e-11 29 156 .. 33 149 .. 10 154 .. 0.87 Alignments for each domain: == domain 1 score: 42.9 bits; conditional E-value: 7.4e-15 PIH1 29 kPepgfvvktsvkgee...KvFiNvcsseliekPeeeegtdeengkkglkwriPyslgqaredkdkkgkkckvyDvvfhpdtlklaekdkefrklv 121 Pep f++ t++ + F+N+cs e+ ++P++e+ +P+ g+ +e+k + + ++ v+D++++p + k ++++k+ ++l+ FUN_000973-T1 33 PPEPCFCISTVMLPSVithELFVNICSWEQMPAPKSEND------------PVPVMAGELQEKK-EGKTTYSVVDIIVNPVVTKGVSNSKDRKNLL 115 69*********988744469**************65544............3899999887665.566799************************* PP PIH1 122 istaleaieqkfevkLdrenlkvlklkykGtleaq 156 +++a+++ e+ +++++ +++k+ k +kG++++ FUN_000973-T1 116 AHVAMDYLENTKKIQVS-RKYKNFKRSFKGDVKTL 149 *****************.99**********98875 PP >> PIH1_CS PIH1 CS-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 0.63 4e+03 32 58 .. 112 138 .. 102 155 .. 0.73 2 ! 34.3 0.1 5.7e-12 3.7e-08 28 99 .. 236 307 .. 228 308 .. 0.92 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.63 PIH1_CS 32 kelvveielPllksakevklrvtekrl 58 k+l +++ + l+ +k++++ ++k++ FUN_000973-T1 112 KNLLAHVAMDYLENTKKIQVSRKYKNF 138 667777888888888888877666665 PP == domain 2 score: 34.3 bits; conditional E-value: 5.7e-12 PIH1_CS 28 stvpkelvveielPl.lksakevklrvtekrlelesekakykLelkLpYpvdeeegkAkFnkkkktLkvtlpV 99 + p+ +vv ++lP+ + s+k+++l+ e++l+l+++ k +L+++Lp +v+ ++ +A+Fn+ k++++v+lp+ FUN_000973-T1 236 NSKPRRVVVLVDLPNsVLSSKDCQLDACETELCLNVPG-KCQLHIDLPEKVNPDQTSATFNTIKHRMVVKLPI 307 456999********7577****************9999.*********************************8 PP >> eIF3g Eukaryotic translation initiation factor 3 subunit G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.4 4.4e-06 0.028 10 74 .. 113 175 .. 102 197 .. 0.86 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 4.4e-06 eIF3g 10 gtktvieykinedgkkvkvtrkiretkvkekvnkavaerkkwaKFGdekgdkpGpnsatttvgee 74 ++ + + e+ kk++v+rk++ + k+ + v +++ K+G+++g + + ++t +++e FUN_000973-T1 113 NLLAHVAMDYLENTKKIQVSRKYK--NFKRSFKGDVKTLRQYLKYGKDHGITVNSGKQTSVISES 175 5555566667799***********..88889*******************999999999999985 PP >> DUF6912 Family of unknown function (DUF6912) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 5.8e-05 0.37 61 114 .. 231 283 .. 226 301 .. 0.65 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 5.8e-05 DUF6912 61 laadeeaprrRvVvaadvpdaav.tadpdldeavvrvagpvplkkvaavHvDeee 114 ++ e+ ++rRvVv +d+p++++ ++d +ld+ + ++ +vp k +H+D +e FUN_000973-T1 231 VKDAENSKPRRVVVLVDLPNSVLsSKDCQLDACETELCLNVPGK--CQLHIDLPE 283 444577888**********8777444445666666665555544..456777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (313 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 951 (0.0372284); expected 510.9 (0.02) Passed bias filter: 674 (0.0263848); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3045.43 // Query: FUN_000974-T1 [L=150] Description: FUN_000974 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (150 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 527 (0.0206303); expected 510.9 (0.02) Passed bias filter: 330 (0.0129184); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.39s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1535.00 // Query: FUN_000975-T1 [L=71] Description: FUN_000975 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (71 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 607 (0.023762); expected 510.9 (0.02) Passed bias filter: 342 (0.0133881); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.22u 0.38s 00:00:00.60 Elapsed: 00:00:00.38 # Mc/sec: 754.92 // Query: FUN_000976-T1 [L=152] Description: FUN_000976 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-08 33.5 0.0 5.7e-08 33.3 0.0 1.1 1 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family Domain annotation for each model (and alignments): >> Exo_endo_phos Endonuclease/Exonuclease/phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.0 2.2e-12 5.7e-08 1 95 [. 21 110 .. 21 126 .. 0.80 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 2.2e-12 xxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Exo_endo_phos 1 ltwNvngg....nadaardparldalaellraydpDvllLQEvdlddaealllallalggyysy...vysggggggggGvailsrfpltsvivrtl 89 l++N+++g +++ ++ + +++++ +pDv++L+Ev+ + ++ l++ + sy +++++ v++l +f + s++++++ FUN_000976-T1 21 LSYNIWFGefmmKER-------MRGIGKIIQERNPDVVALNEVTRENLAMLREQPWF----DSYnvlPT-DIQNQNSYFVVLLTKFMIHSWKIDPF 104 79*****98776554.......666**********************9998877753....33322222.3678*****************99999 PP xxxxxx RF Exo_endo_phos 90 sedgdp 95 + +++ FUN_000976-T1 105 KNSCFG 110 887665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (152 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 648 (0.025367); expected 510.9 (0.02) Passed bias filter: 519 (0.0203171); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1532.34 // Query: FUN_000977-T1 [L=851] Description: FUN_000977 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-95 319.2 0.0 4.9e-95 318.2 0.0 1.5 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.8e-47 162.4 0.0 4.4e-47 161.2 0.0 1.6 1 Pkinase Protein kinase domain 1.1e-16 61.2 0.0 4.1e-16 59.3 0.0 2.1 1 SH2 SH2 domain 1.1e-10 42.1 0.3 5.7e-10 39.8 0.3 2.3 1 FCH Fes/CIP4, and EFC/F-BAR homology domain ------ inclusion threshold ------ 0.072 13.6 0.9 0.25 11.9 0.9 1.9 1 Phage_RpbA Phage RNA polymerase binding, RpbA 2.3 9.1 18.5 2.2 9.2 4.3 3.4 3 OVT1 Major antigen, helical domain 5.8 7.5 16.5 0.2 12.2 4.4 2.7 2 CENP-Q CENP-Q, a CENPA-CAD centromere complex subuni Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 318.2 0.0 1.4e-98 4.9e-95 5 258 .] 596 844 .. 592 844 .. 0.98 Alignments for each domain: == domain 1 score: 318.2 bits; conditional E-value: 1.4e-98 PK_Tyr_Ser-Thr 5 eklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkkkekl 99 +klG+G+fG+V+kg+lk ++i+VavK++k++ s+ k++fl+ea+++k+++hpnivkl+gvc e+ep++iv+e+++gG+++++Lrkk ++l FUN_000977-T1 596 NKLGQGHFGDVMKGILK----PENIPVAVKSCKQNVSQVVKTKFLAEAEILKQYDHPNIVKLIGVCAEKEPVFIVMEFMPGGDFLSYLRKKASQL 686 69***************....899*********************************************************************** PP PK_Tyr_Ser-Thr 100 slkellklalqiAkGmeyLeskklvHrdlaarNvLvse.kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDvWsfGvl 193 + ++llk++++ A+GmeyLe k+++HrdlaarN+L+s+ ++v kisDfG++r+v d+ y++++ +++p+kW+apE+l++ k+t+ sD+WsfG+l FUN_000977-T1 687 NSRKLLKFSVDAAAGMEYLEGKNCIHRDLAARNCLISSgDSVLKISDFGMSREV--DEVYEASNMKEIPVKWTAPEALNYFKYTTLSDIWSFGIL 779 *************************************956699***********..99************************************* PP PK_Tyr_Ser-Thr 194 lwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelveel 258 lwE f++g++py+gl+n+e+ +++e+g+r++ p+ +p+++y++mk+Cw+ d+++Rp+f+e++++l FUN_000977-T1 780 LWETFSYGNTPYPGLNNRETRDRVETGYRMSSPTGTPPAVYQIMKDCWNFDADQRPRFSEILRRL 844 *************************************************************9876 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 161.2 0.0 1.2e-50 4.4e-47 5 258 .. 596 842 .. 593 844 .. 0.91 Alignments for each domain: == domain 1 score: 161.2 bits; conditional E-value: 1.2e-50 Pkinase 5 eklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkga.lseee 99 +klG+G+fg V+k++ k ++ vA+K k++ + k +k+l+E +ilk+++hpniv+li+v+ ek+ +++v+E+++gg++ ++l++k + l++++ FUN_000977-T1 596 NKLGQGHFGDVMKGILKPENIPVAVKSCKQNVSQVVK-TKFLAEAEILKQYDHPNIVKLIGVCAEKEPVFIVMEFMPGGDFLSYLRKKASqLNSRK 690 69***************************99888877.59****************************************99999977666***** PP Pkinase 100 akkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakelesssk.ltsfvgtseYmAPEvlkskkygkkvDvWslGvilyell.t 192 + k+ + g+eyl ++++HrDl N Li+ ++ lKi+DFG+++e+++ + + + ++ APE l++ ky++ +D+Ws G++l+e + + FUN_000977-T1 691 LLKFSVDAAAGMEYLEGKNCIHRDLAARNCLISsGDSVLKISDFGMSREVDEVYEaSNMKEIPVKWTAPEALNYFKYTTLSDIWSFGILLWETFsY 786 *********************************55666**************999666677889***************************98736 PP Pkinase 193 gkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellq 258 g++p+++ ++ e +++ ++e+ + p+ + + +++k++++ d ++R+ ++e+l+ FUN_000977-T1 787 GNTPYPGLNNRE-----TRD-----RVETGYRMSSPTGTPPAVYQIMKDCWNFDADQRPRFSEILR 842 9*****555554.....333.....34556778888999*********************999986 PP >> SH2 SH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.3 0.0 1.1e-19 4.1e-16 1 77 [] 488 560 .. 488 560 .. 0.98 Alignments for each domain: == domain 1 score: 59.3 bits; conditional E-value: 1.1e-19 SH2 1 WyhgkisrkeaerlLleekkdGtFLvReSeskpGdytlsvvddgkvkhykiqstdngkyyiaegekfsslaeLvehY 77 W++g i rk++ l ++ dG++LvReS +kpG+++ls + +g kh+ iq +d+g ++++e+e f s+ eL +h+ FUN_000977-T1 488 WFYGTIDRKDVPALVKR---DGDYLVRESCTKPGQFVLSTRLQGAPKHFIIQMSDDG-LVRFEDEGFPSVRELLDHH 560 ************99998...************************************8.******************8 PP >> FCH Fes/CIP4, and EFC/F-BAR homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.8 0.3 1.6e-13 5.7e-10 1 74 [. 19 91 .. 19 92 .. 0.96 Alignments for each domain: == domain 1 score: 39.8 bits; conditional E-value: 1.6e-13 FCH 1 gfkvLlkrlkqgiklleelakflkeRaeiEeeYakkLqklakkylkkkkepedeegtlkkawdellteteqlak 74 g+++++++++ ++k le ++++l +Ra++E eYa L +++ + k +++ +d+e+ ++kaw +++ e e+ ak FUN_000977-T1 19 GHEAIVAHIEGELKHLEHVKEYLIKRAKVELEYASALARISAAAAKAISD-SDRESPIRKAWCTYIAESESKAK 91 899*******************************************9976.8899***************9886 PP >> Phage_RpbA Phage RNA polymerase binding, RpbA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.9 6.7e-05 0.25 15 95 .. 71 153 .. 61 155 .. 0.85 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 6.7e-05 Phage_RpbA 15 nqnkiRkaWVlqisd..eeaeklqaleqevrfelYkeiDkeVsdkwielmrkhredslaagaklvkdk.gkerledeycvdtDe 95 + iRkaW + i + ++a+++ ++ k + + +dk +l+rk+++++ + +++ + +rl++ y++++ e FUN_000977-T1 71 RESPIRKAWCTYIAEseSKAKMITEFTNNLNSSTLKRLEQLLEDKR-SLLRKYTQEKFRVDSSFKQETaEIDRLKKTYQDNARE 153 5778******9996511567899999999*********99998886.9****************999999*********99866 PP >> OVT1 Major antigen, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 2.2 8e+03 22 37 .. 29 44 .. 24 59 .. 0.76 2 ? 5.5 4.5 0.0085 31 23 77 .. 107 165 .. 97 199 .. 0.77 3 ? 9.2 4.3 0.00061 2.2 21 68 .. 311 358 .. 306 390 .. 0.83 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 2.2 OVT1 22 aalknleelkrkllkd 37 +lk+le++k+ l+k FUN_000977-T1 29 GELKHLEHVKEYLIKR 44 5788999988888875 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0085 OVT1 23 alknleelkrkllkdlenqrarldav....tseldklqteyesatkntvaieqtvkElk 77 l++l e kr+ll+++++++ r+d t+e+d+l+++y+ + +++ + + + E+ FUN_000977-T1 107 RLEQLLEDKRSLLRKYTQEKFRVDSSfkqeTAEIDRLKKTYQDNARESETGKRKYGEVY 165 456666899***********999965444489***********9999999888888874 PP == domain 3 score: 9.2 bits; conditional E-value: 0.00061 OVT1 21 daalknleelkrkllkdlenqrarldavtseldklqteyesatkntva 68 d ++++l++ ++ l kdlen +++ld ++e+++ + ++++ +k++ FUN_000977-T1 311 DLTMEKLQHKRTLLSKDLENVKQQLDDKQKEFEQENCKLKTVKKESED 358 67899999**************************99999999998754 PP >> CENP-Q CENP-Q, a CENPA-CAD centromere complex subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 4.4 5.6e-05 0.2 29 107 .. 103 181 .. 93 213 .. 0.85 2 ? -0.0 4.3 0.33 1.2e+03 23 65 .. 313 355 .. 305 402 .. 0.56 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 5.6e-05 CENP-Q 29 denkaleaqlsaelhslelLeeeiekeeallesdeeyleeLeknakaeererkeelkkehpllqeddsevlsllelssd 107 + k+le+ l+ + l + +e+ ++ + +++++++ +L+k+ + ++re + ++k ++ +d+ ++++ + +++ FUN_000977-T1 103 STLKRLEQLLEDKRSLLRKYTQEKFRVDSSFKQETAEIDRLKKTYQDNARESETGKRKYGEVYSKDKFNNKDWERAKDR 181 56799**********************************************9998899888888777777776665554 PP == domain 2 score: -0.0 bits; conditional E-value: 0.33 CENP-Q 23 dfeklldenkaleaqlsaelhslelLeeeiekeeallesdeey 65 +ekl ++ + l++ l+ +++l++ ++e+e+e l+ +++ FUN_000977-T1 313 TMEKLQHKRTLLSKDLENVKQQLDDKQKEFEQENCKLKTVKKE 355 4555555555555555555555555555555555444444333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (851 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2413 (0.0944608); expected 510.9 (0.02) Passed bias filter: 854 (0.0334312); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.45u 0.38s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 8204.05 // Query: FUN_000979-T1 [L=591] Description: FUN_000979 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0022 16.5 0.1 0.0032 15.9 0.1 1.2 1 SrfB Virulence factor SrfB Domain annotation for each model (and alignments): >> SrfB Virulence factor SrfB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 1.2e-07 0.0032 876 959 .. 3 86 .. 1 98 [. 0.88 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 1.2e-07 SrfB 876 lddkdyeldpeaafelrgsvslGfRqlaaerWpatplylldlaneelaeklakdgvlkvelkvkkkdkdeevaealeiaeaedk 959 l+++++++ e+ ++ g+v +GfR++a++ W+++p +++ +ee+++ + +++ l+ +++ ++++++++++ +l++++ +k FUN_000979-T1 3 LNSPQFSTVLEEMNNIGGKVNMGFRKVATNSWSSAPEIQITCFEEEIRNDQVQETGLENRFEETNQKTKQKAIKTLTLHQSSEK 86 66677777777788899***************************************************9999999999876655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (591 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1121 (0.0438833); expected 510.9 (0.02) Passed bias filter: 456 (0.0178509); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5808.51 // Query: FUN_000980-T1 [L=370] Description: FUN_000980 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-53 180.2 0.0 9.5e-53 180.0 0.0 1.0 1 Aminotran_5 Aminotransferase class-V Domain annotation for each model (and alignments): >> Aminotran_5 Aminotransferase class-V # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 180.0 0.0 3.7e-57 9.5e-53 2 371 .] 9 356 .. 8 356 .. 0.91 Alignments for each domain: == domain 1 score: 180.0 bits; conditional E-value: 3.7e-57 Aminotran_5 2 yldsaAttqkpqeVldalqeyytdyngnvhr..svhtlgkeatkaveearekvaefinaeseeeiiFtsGtte.ainlvalslarslkkgdeivit 94 ++ ++++++p+eVl+++q++ +y g + + ++++++++++k+v+ea+++ +e+++++++++++F++G+++ +++v+l+l ++g+++ + FUN_000980-T1 9 LNFAPGPAKIPEEVLAQAQKEMVNYEGLGISvmEMSHRSAHFAKIVNEAESDLRELLGIPDNYKVLFLQGGGTgEFAAVPLNL---AREGKSADYI 101 68999**************************99*************************************9998*********...6799999999 PP Aminotran_5 95 elehhanlvpwqelakrtgakvkvlpldeegeldldeleklisektklvaithvsnvlGt.iqpveeigklahkkgalvlvDaaqavghipidvkk 189 ++ +++ +++e++k+t++k + +ld+ ++ + e+++++++++v+++++++v+G+ ++ v+e g+ +++D++++++++p+dv+k FUN_000980-T1 102 ITGAWSAK-AAKEAEKFTKVKPVLKKLDKYDRIP-PQSEWNLDPNASYVYYCANETVHGVeFDFVPETN------GIPLVCDMSSTFLSRPVDVSK 189 99******.************9999999998887.6789*********************777888877......********************* PP Aminotran_5 190 lgvDflafSghKllGPtGiGvlygrkellekleplllGGkmveevsl.eeatlaeapskfeaGTpniagiiglgaaleyl.eeigleaiekhekel 283 +g ++++++K++G +G++v+++r++l+ + +p ++ + +++++a++ s+++ Tp++++i+ +g +++++ + +g+e+++++++ + FUN_000980-T1 190 FGL--IYAGAQKNVGCAGVTVVIVRDDLISNPSPQ--------CPIVfDYKVQAGNNSMYN--TPPTFNIYIMGLVFKWIkKVGGVEEMDRRNDIK 273 ***..**************************9554........555559999*********..*****************77789*********** PP Aminotran_5 284 aeyllerLeslpgvrlygpdkaeerasiisfnfkgvha....edvatlLdee..gIavra.GhhcaqplmkrlalegtvRaSlylynteedvdal 371 ++ l++ ++s++g+ + g +++++ +s ++ +++ ++ e +t+++e+ + +++ Gh+++ g++R+S+y++ + edv+ l FUN_000980-T1 274 SNLLYNLIDSSNGFYC-G-TVEKKSRSRMNAPLRIASPsgdqELEKTFIEEAaaKNMIQLkGHRSV----------GGIRVSMYNAIKPEDVNTL 356 **************99.7.588999999998887766655547788888887533345448*****..........****************876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (370 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 572 (0.0223919); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3744.08 // Query: FUN_000982-T1 [L=130] Description: FUN_000982 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.4e-20 71.2 18.9 1e-11 44.9 9.3 3.0 3 LRR_8 Leucine rich repeat 5.7e-11 42.9 1.6 7.3e-11 42.6 1.6 1.1 1 LRR_5 BspA type Leucine rich repeat region (6 copies 1.5e-08 35.1 19.5 1.9e-05 25.2 4.7 2.7 3 LRR_4 Leucine Rich repeats (2 copies) 0.0005 20.1 15.6 0.8 10.6 0.5 4.6 5 LRR_1 Leucine Rich Repeat 0.003 17.6 3.5 0.0067 16.5 3.0 1.5 1 LRR_9 Leucine-rich repeat ------ inclusion threshold ------ 0.22 11.9 0.0 0.35 11.3 0.0 1.5 1 Peptidase_S26 Signal peptidase, peptidase S26 0.24 12.1 3.9 0.86 10.3 3.5 2.0 2 LRR_EndoS Endo-beta-N-acetylglucosaminidase EndoS LRR do 7 6.7 7.3 3 7.9 1.4 2.3 2 zf-C2H2_FBX41 F-box only protein 41 C2H2 zinc finger Domain annotation for each model (and alignments): >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.9 9.3 3.2e-15 1e-11 8 61 .] 10 63 .. 9 63 .. 0.98 2 ! 34.6 6.5 5.1e-12 1.6e-08 3 45 .. 53 95 .. 53 109 .. 0.89 3 ? 3.9 0.0 0.02 65 2 24 .. 101 123 .. 100 127 .. 0.77 Alignments for each domain: == domain 1 score: 44.9 bits; conditional E-value: 3.2e-15 LRR_8 8 LssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 L+ N ++sld ++F++ls+Lk L Ls N+lt l +++f++ ++L++L L++N + FUN_000982-T1 10 LNGNLIKSLDSSTFSSLSSLKLLVLSGNKLTNLTRESFHNIKALKYLFLNDNLI 63 899*************************************************87 PP == domain 2 score: 34.6 bits; conditional E-value: 5.1e-12 LRR_8 3 LrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgaf 45 L++L L++N ++sld +aF+gls+L+ L+L +N l+ l+++af FUN_000982-T1 53 LKYLFLNDNLIKSLDSHAFRGLSSLELLNLADNPLQELNDNAF 95 7899999999999999999999999999999999999999999 PP == domain 3 score: 3.9 bits; conditional E-value: 0.02 LRR_8 2 nLrsLdLssNrltslddgaFkgl 24 +L+ ++L +++ + ++ +aF+g FUN_000982-T1 101 SLHAIYLMNTSMERINIKAFEGQ 123 68888888888888888888874 PP >> LRR_5 BspA type Leucine rich repeat region (6 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.6 1.6 2.3e-14 7.3e-11 21 123 .. 14 123 .. 3 127 .. 0.85 Alignments for each domain: == domain 1 score: 42.6 bits; conditional E-value: 2.3e-14 LRR_5 21 sltsIgeyaFsnctslksitlps.sltsigsyaFsnc.slesitipss.ltsigeyaFsncsnlksitlpen.ltsigssaF..sncslksitips 110 ++s+++++Fs+ +slk + l+ +lt++ +++F n l+ + ++++ ++s++++aF++ s+l+ ++l n l++++++aF +n+sl i++ + FUN_000982-T1 14 LIKSLDSSTFSSLSSLKLLVLSGnKLTNLTRESFHNIkALKYLFLNDNlIKSLDSHAFRGLSSLELLNLADNpLQELNDNAFniANSSLHAIYLMN 109 578999999999999999999762699999999999988999999985489999999999999999999887799999999954567999999887 PP LRR_5 111 .svtkigeyaFsnc 123 s+++i+ +aF++ FUN_000982-T1 110 tSMERINIKAFEGQ 123 69999999999987 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 5.0 3.3e-06 0.01 8 39 .. 10 42 .. 9 46 .. 0.89 2 ! 25.2 4.7 6e-09 1.9e-05 2 41 .. 52 92 .. 51 95 .. 0.87 3 ? -0.9 0.1 0.97 3.1e+03 24 33 .. 101 109 .. 90 121 .. 0.56 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 3.3e-06 LRR_4 8 LsnNritdidp..lskLpnLetLdLsgNnkitdl 39 L++N i+++d+ +s+L +L+ L LsgN k+t+l FUN_000982-T1 10 LNGNLIKSLDSstFSSLSSLKLLVLSGN-KLTNL 42 89*********87779*********999.88777 PP == domain 2 score: 25.2 bits; conditional E-value: 6e-09 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitdlsd 41 L++L L++N i+++d+ +++L +Le L+L++N ++++l+d FUN_000982-T1 52 ALKYLFLNDNLIKSLDShaFRGLSSLELLNLADN-PLQELND 92 69***************88779*********777.7777765 PP == domain 3 score: -0.9 bits; conditional E-value: 0.97 LRR_4 24 nLetLdLsgN 33 +L+ ++L N FUN_000982-T1 101 SLHAIYL-MN 109 3444444.33 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.4 0.3 9.4e+02 7 23 .] 10 26 .. 9 26 .. 0.87 2 ! 10.6 0.5 0.00025 0.8 1 22 [. 28 49 .. 28 50 .. 0.91 3 ! 7.9 0.1 0.002 6.5 2 23 .] 53 74 .. 52 74 .. 0.91 4 ! 8.5 0.3 0.0013 4.2 1 20 [. 76 95 .. 76 98 .. 0.84 5 ? -1.5 0.0 2.8 9.1e+03 2 20 .. 102 120 .. 101 122 .. 0.69 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.3 LRR_1 7 LsnNnlsgllpeslgnl 23 L++N + +l+++++++l FUN_000982-T1 10 LNGNLIKSLDSSTFSSL 26 89999*99999999886 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00025 LRR_1 1 nLeeLdLsnNnlsgllpeslgn 22 +L+ L Ls+N+l+ l es+ n FUN_000982-T1 28 SLKLLVLSGNKLTNLTRESFHN 49 799**********999999987 PP == domain 3 score: 7.9 bits; conditional E-value: 0.002 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L++L L++N + +l+++++++l FUN_000982-T1 53 LKYLFLNDNLIKSLDSHAFRGL 74 99*********99999999876 PP == domain 4 score: 8.5 bits; conditional E-value: 0.0013 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +Le L+L++N+l +l +++ FUN_000982-T1 76 SLELLNLADNPLQELNDNAF 95 79**********87776665 PP == domain 5 score: -1.5 bits; conditional E-value: 2.8 LRR_1 2 LeeLdLsnNnlsgllpesl 20 L ++L n++ + + + ++ FUN_000982-T1 102 LHAIYLMNTSMERINIKAF 120 7778888888776666666 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 3.0 2.1e-06 0.0067 47 128 .. 9 90 .. 2 102 .. 0.82 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 2.1e-06 LRR_9 47 idlsdneirkldg..fPllkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslkkltslsllrnpvtnk 128 + l n i+ ld+ f l lk l+l n++++++ + + + l+ l l +n +++l + + l++l+ l l +np+ + FUN_000982-T1 9 L-LNGNLIKSLDSstFSSLSSLKLLVLSGNKLTNLTRESFHNIKALKYLFLNDNLIKSLDS-HAFRGLSSLELLNLADNPLQEL 90 5.66788888885338889999999999999999999999999999999999999999977.8999999999999999998765 PP >> Peptidase_S26 Signal peptidase, peptidase S26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00011 0.35 126 151 .. 46 71 .. 11 86 .. 0.79 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00011 Peptidase_S26 126 gekkvpegeyFvlgdnrdnSlDSRyf 151 +++++ +y++l+dn +SlDS+ f FUN_000982-T1 46 SFHNIKALKYLFLNDNLIKSLDSHAF 71 23569******************987 PP >> LRR_EndoS Endo-beta-N-acetylglucosaminidase EndoS LRR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 3.5 0.00027 0.86 32 99 .. 20 92 .. 9 109 .. 0.65 2 ? 6.3 0.3 0.0048 15 28 93 .. 56 121 .. 54 127 .. 0.56 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00027 LRR_EndoS 32 npeikdLtGlekl....kklkkltlkgltklkelsesslpesl.kkekelelkgltaLktldlsglkleklea 99 + +L l+ l +kl++lt + +++k l+ l ++l k+ ++ +gl++L+ l+l++ l++l++ FUN_000982-T1 20 SSTFSSLSSLKLLvlsgNKLTNLTRESFHNIKALKYLFLNDNLiKSLDSHAFRGLSSLELLNLADNPLQELND 92 5555555555554222236777777777777777777777775144446777888888888888888888876 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0048 LRR_EndoS 28 LkldnpeikdLtGleklkklkkltlkgltk..lkelsesslpeslkkekelelkgltaLktldlsglk 93 L l++ ik+L+ + + +l++l+l +l + l+el+++ + + + + + l + t++++++++ ++ FUN_000982-T1 56 LFLNDNLIKSLDS-HAFRGLSSLELLNLADnpLQELNDNAFNIANSSLHAIYLMN-TSMERINIKAFE 121 5667777777765.56777777777777542366666666554444444555555.345666665555 PP >> zf-C2H2_FBX41 F-box only protein 41 C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 1.4 0.00095 3 10 21 .. 19 30 .. 18 33 .. 0.88 2 ? 1.8 0.4 0.076 2.4e+02 12 21 .. 69 78 .. 67 80 .. 0.81 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.00095 zf-C2H2_FBX41 10 ehkRFrSLssLR 21 +++ F+SLssL+ FUN_000982-T1 19 DSSTFSSLSSLK 30 6789*******7 PP == domain 2 score: 1.8 bits; conditional E-value: 0.076 zf-C2H2_FBX41 12 kRFrSLssLR 21 Fr LssL+ FUN_000982-T1 69 HAFRGLSSLE 78 56*******6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 686 (0.0268546); expected 510.9 (0.02) Passed bias filter: 435 (0.0170288); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1312.36 // Query: FUN_000983-T1 [L=89] Description: FUN_000983 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-14 54.6 0.2 3.4e-14 53.2 0.2 1.6 1 I-set Immunoglobulin I-set domain 2.5e-14 53.8 0.1 2.7e-14 53.6 0.1 1.0 1 Ig_2 Immunoglobulin domain 4e-13 50.1 0.1 5e-13 49.8 0.1 1.2 1 Ig_3 Immunoglobulin domain 5.5e-11 43.1 0.2 7.6e-11 42.7 0.2 1.2 1 ig Immunoglobulin domain 2.4e-06 28.2 0.6 5.5e-05 23.8 0.2 2.0 2 V-set Immunoglobulin V-set domain 2.6e-05 24.7 0.2 0.017 15.6 0.0 2.0 2 Ig_PDGFR_d4 Platelet-derived growth factor receptor 4.4e-05 24.5 0.0 4.8e-05 24.3 0.0 1.1 1 Ig_4 T-cell surface glycoprotein CD3 delta ch 0.00036 21.4 0.0 0.00044 21.1 0.0 1.1 1 Ig_5 Ig-like domain on T-cell surface glycopr 0.0006 20.5 0.2 1 10.0 0.1 2.1 2 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain ------ inclusion threshold ------ 0.019 15.4 0.1 0.021 15.2 0.1 1.3 1 Izumo-Ig Izumo-like Immunoglobulin domain 0.035 14.6 0.2 0.097 13.2 0.2 1.7 1 C2-set_2 CD80-like C2-set immunoglobulin domain 0.043 14.0 0.1 0.054 13.7 0.1 1.2 1 ICAM_N Intercellular adhesion molecule (ICAM), 0.066 13.7 0.0 0.09 13.2 0.0 1.3 1 bMG3 Bacterial alpha-2-macroglobulin MG3 doma 0.16 12.5 0.1 0.62 10.6 0.1 1.8 1 Ig_C17orf99 C17orf99 Ig domain 0.2 12.4 0.0 0.21 12.4 0.0 1.2 1 PITM1-3 PITM 1-3, beta-sandwich domain Domain annotation for each model (and alignments): >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.2 0.2 2e-17 3.4e-14 10 90 .] 14 86 .. 5 86 .. 0.91 Alignments for each domain: == domain 1 score: 53.2 bits; conditional E-value: 2e-17 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 v +G + el c++sG p+p+v W+k g e++e +g+a L ++nvk +++G+Y+c+a+ns g+++ +++LtV FUN_000983-T1 14 HFVLKGRKTELRCSASGLPTPNVMWTKLGVEVTE--------GNGSAVLSLNNVKTDNQGIYRCTANNSQGQKSDTMKLTV 86 56889************************99996........457899*******************************98 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.6 0.1 1.6e-17 2.7e-14 7 79 .] 11 86 .. 4 86 .. 0.85 Alignments for each domain: == domain 1 score: 53.6 bits; conditional E-value: 1.6e-17 Ig_2 7 sptv.vtegesvtLtCsasgnppakytwykdgkvlsssqn...fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++++ v +g + L+Csasg p+++++w+k g ++ ++ ++++nv +++G+Y+Cta n ++g++s+++++tv FUN_000983-T1 11 TASHfVLKGRKTELRCSASGLPTPNVMWTKLGVEVTEGNGsavLSLNNVKTDNQGIYRCTANN-SQGQKSDTMKLTV 86 45444899************************99996655575556*****************.6699999**9998 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.8 0.1 3e-16 5e-13 2 78 .] 5 73 .. 4 73 .. 0.85 Alignments for each domain: == domain 1 score: 49.8 bits; conditional E-value: 3e-16 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P i+ s+ v +g + +L+C+a+g p+p++ W+k g ++ t+ ++++++L+++nv+ +++G Y+C+A+N FUN_000983-T1 5 PLIVDMTASHFVLKGRKTELRCSASGLPTPNVMWTKLGV---EV-TE----GNGSAVLSLNNVKTDNQGIYRCTANN 73 5555444455599**************************...53.33....7899********************99 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.7 0.2 4.5e-14 7.6e-11 2 79 .. 13 80 .. 12 82 .. 0.94 Alignments for each domain: == domain 1 score: 42.7 bits; conditional E-value: 4.5e-14 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 ++ vl+G + +L+Csas g p p+v+W k g + +e+ ++ l ++nv+ ++ G Y+C++nn+ g+++ FUN_000983-T1 13 SHFVLKGRKTELRCSAS-GLPTPNVMWTKLGVEVTEGNG---------SAVLSLNNVKTDNQGIYRCTANNSQGQKSD 80 7899*************.*******************66.........*************************99876 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.078 1.3e+02 9 35 .. 17 40 .. 12 44 .. 0.84 2 ! 23.8 0.2 3.2e-08 5.5e-05 66 109 .] 47 87 .. 40 87 .. 0.90 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.078 V-set 9 aeGesvtLtCslssseseasqsvyWyr 35 G + +L+Cs s ++ v W++ FUN_000983-T1 17 LKGRKTELRCSASGL---PTPNVMWTK 40 57999*****99988...899999987 PP == domain 2 score: 23.8 bits; conditional E-value: 3.2e-08 V-set 66 kdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtVl 109 + ++++ l ++n++ +++G+Y C ++++++++ +++LtV+ FUN_000983-T1 47 E--GNGSAVLSLNNVKTDNQGIYRCT-ANNSQGQKSDTMKLTVV 87 4..78999******************.9**************95 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 9.9e-06 0.017 3 33 .. 7 39 .. 5 42 .. 0.79 2 ! 7.8 0.1 0.0024 4.2 81 108 .. 58 85 .. 39 88 .. 0.78 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 9.9e-06 Ig_PDGFR_d4 3 ilelsdsh..assgeqtvtCvaeGmPqPeveWf 33 i++++ sh + ++ ++C a G+P+P+v W FUN_000983-T1 7 IVDMTASHfvLKGRKTELRCSASGLPTPNVMWT 39 66677666334667889***************6 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0024 Ig_PDGFR_d4 81 fqkveetlavrCeaknelgadsrevkLv 108 k++++ rC+a+n+ g++s +kL FUN_000983-T1 58 NVKTDNQGIYRCTANNSQGQKSDTMKLT 85 3456788889***********9999985 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.0 2.8e-08 4.8e-05 6 59 .. 24 83 .. 19 89 .] 0.75 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 2.8e-08 Ig_4 6 LtCnsss...keitwlkdgkeikeskek.tldlgksiedprglYqCk..eeekkkssslq 59 L+C+ s +++w k g e +e + + l+l+++ +d++g+Y+C+ +++ +ks +++ FUN_000983-T1 24 LRCSASGlptPNVMWTKLGVEVTEGNGSaVLSLNNVKTDNQGIYRCTanNSQGQKSDTMK 83 777444332368*****99999998888799****************7644555555554 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 2.6e-07 0.00044 6 67 .. 18 82 .. 14 87 .. 0.76 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 2.6e-07 Ig_5 6 sgttVtltCpeese..eeikWekndkelkdkeek.eLvlenFsevedsGyysCykesskk.akhyL 67 g++ +l+C+ + ++ W k + e+++ +++ L+l+n ++++G y C++++s+ ++ ++ FUN_000983-T1 18 KGRKTELRCSASGLptPNVMWTKLGVEVTEGNGSaVLSLNN-VKTDNQGIYRCTANNSQGqKSDTM 82 689999***976434499*******9999866551577776.778**********99976455555 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.00092 1.6 23 42 .. 20 39 .. 8 52 .. 0.83 2 ! 10.0 0.1 0.00061 1 93 121 .. 54 83 .. 39 88 .. 0.74 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00092 Ig_VEGFR-1-like_5th 23 qrhkltctafgipmpnitwf 42 ++ +l c+a g+p pn+ w FUN_000983-T1 20 RKTELRCSASGLPTPNVMWT 39 46789**************6 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00061 Ig_VEGFR-1-like_5th 93 istlvvktanvsgvysctarnelgnr..tmr 121 +s vkt n g+y cta n g++ tm+ FUN_000983-T1 54 LSLNNVKTDN-QGIYRCTANNSQGQKsdTMK 83 4555688877.7***********98722444 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.1 1.2e-05 0.021 44 74 .. 46 77 .. 14 88 .. 0.78 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.2e-05 Izumo-Ig 44 skgk.estLtkpmvgledaGtYRCeLdtvkss 74 ++g+ ++L ++ v+++++G YRC+ ++ + FUN_000983-T1 46 TEGNgSAVLSLNNVKTDNQGIYRCTANNSQGQ 77 4555145799**************98876544 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.2 5.7e-05 0.097 14 42 .. 19 51 .. 5 80 .. 0.77 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 5.7e-05 C2-set_2 14 ekevvatCvsaggkPapritWlldgkel.....e 42 +++ ++C sa+g P+p+++W + g e+ + FUN_000983-T1 19 GRKTELRC-SASGLPTPNVMWTKLGVEVtegngS 51 568889**.99***********999998444442 PP >> ICAM_N Intercellular adhesion molecule (ICAM), N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 3.2e-05 0.054 38 85 .. 38 86 .. 7 88 .. 0.72 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.2e-05 ICAM_N 38 EtslsKelleegqgwkafelsnvsedsv..llCyvtCsgkqssassnitv 85 t+l ++ eg+g ++ l nv+ d + C + s+ q+s ++tv FUN_000983-T1 38 WTKLG-VEVTEGNGSAVLSLNNVKTDNQgiYRCTANNSQGQKSDTMKLTV 86 33332.467789*************998335699999999**99999998 PP >> bMG3 Bacterial alpha-2-macroglobulin MG3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 5.3e-05 0.09 42 71 .. 55 84 .. 28 88 .. 0.77 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 5.3e-05 bMG3 42 vLakakTDaqGlarfeaklakgkeaakpal 71 L + kTD+qG++r +a++++g+++++ +l FUN_000983-T1 55 SLNNVKTDNQGIYRCTANNSQGQKSDTMKL 84 47889*************999998887665 PP >> Ig_C17orf99 C17orf99 Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 0.00036 0.62 15 91 .. 18 86 .. 7 89 .] 0.66 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00036 Ig_C17orf99 15 ksrrvlisChasegspPItYsLvgkkgivvakkivkegkPAnFsllitlkssPdlltyaCqAantsgvqasslvLql 91 k+r+ ++ C as + P + k g++v++ +g A sl+ ++ + y C A+n+ g+++++ L + FUN_000983-T1 18 KGRKTELRCSASGLPTPN--VMWTKLGVEVTEG---NG-SAVLSLNNVKTDN--QGIYRCTANNSQGQKSDTMKLTV 86 566666666666555553..3445555555443...33.5667776555544..678*************9999876 PP >> PITM1-3 PITM 1-3, beta-sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00012 0.21 46 83 .. 34 71 .. 11 86 .. 0.84 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00012 PITM1-3 46 ksgewtllstevtdksGrisytlpeekalglGlypvkm 83 ++ wt l+ evt+ +G ++l++ k+ + G+y+ + FUN_000983-T1 34 PNVMWTKLGVEVTEGNGSAVLSLNNVKTDNQGIYRCTA 71 5678******************************9765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (89 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 553 (0.0216481); expected 510.9 (0.02) Passed bias filter: 430 (0.016833); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 910.67 // Query: FUN_000984-T1 [L=1262] Description: FUN_000984 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-29 100.8 0.1 1.3e-28 100.0 0.1 1.5 1 CUB CUB domain 3.2e-28 97.8 40.2 4.2e-11 42.9 7.0 5.7 6 LRR_8 Leucine rich repeat 7.1e-14 52.1 0.0 1.4e-13 51.2 0.0 1.5 1 I-set Immunoglobulin I-set domain 1.2e-13 51.5 0.0 2.9e-13 50.4 0.0 1.6 1 Ig_2 Immunoglobulin domain 6.2e-13 49.5 0.2 1.8e-12 48.1 0.0 1.9 1 Ig_3 Immunoglobulin domain 3e-12 47.0 5.8 2.7e-08 34.3 2.4 3.0 2 LRR_5 BspA type Leucine rich repeat region (6 2.6e-11 44.1 0.1 4.9e-11 43.3 0.1 1.5 1 ig Immunoglobulin domain 7.7e-10 39.2 41.0 0.0006 20.5 4.9 6.2 7 LRR_4 Leucine Rich repeats (2 copies) 5.8e-07 29.7 9.4 0.0019 18.3 3.4 2.4 2 LRR_9 Leucine-rich repeat 1.7e-05 25.4 0.7 0.0012 19.5 0.0 3.0 3 V-set Immunoglobulin V-set domain 3.7e-05 23.7 1.3 3.7e-05 23.7 1.3 3.1 3 LRRNT Leucine rich repeat N-terminal domain 0.0016 19.5 0.2 0.0058 17.7 0.2 2.1 1 Ig_4 T-cell surface glycoprotein CD3 delta ch 0.0034 17.6 25.2 0.12 12.7 3.8 5.2 4 Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B 0.007 15.7 0.0 0.017 14.5 0.0 1.5 1 TRP Transient receptor potential (TRP) ion c 0.007 16.9 11.3 0.007 16.9 11.3 3.1 2 DUF7630 Domain of unknown function (DUF7630) ------ inclusion threshold ------ 0.025 15.0 23.3 0.16 12.4 0.3 6.1 5 TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like 0.039 14.6 0.1 5.3 7.7 0.0 2.6 2 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.093 12.8 0.0 0.19 11.8 0.0 1.4 1 CDCP1_CUB_6 CDCP1 CUB domain 0.2 12.2 0.0 0.56 10.8 0.0 1.8 1 C2-set_2 CD80-like C2-set immunoglobulin domain 0.23 12.2 33.9 26 6.1 0.5 9.2 8 LRR_1 Leucine Rich Repeat 0.26 11.8 0.0 0.26 11.8 0.0 3.5 2 Ig_PDGFR_d4 Platelet-derived growth factor receptor 0.55 11.0 2.7 11 6.8 0.1 2.7 2 DUF4381 Domain of unknown function (DUF4381) 4 8.1 14.6 2.3 8.8 0.2 3.3 2 CcmD Heme exporter protein D (CcmD) Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.0 0.1 1.2e-31 1.3e-28 1 110 [] 25 140 .. 25 140 .. 0.93 Alignments for each domain: == domain 1 score: 100.0 bits; conditional E-value: 1.2e-31 CUB 1 Cgge.ltessgsisspnypkeYeenkeCvweirvekgks.....vklkfedfeleeeeecaydyvevrdgeeasskllgkfcGsekpediksssnq 90 C+++ + +++gs++spnyp++Y++ ++C+w i+++++ +kl+f++f++e + +c+yd v v+dg +++++l+g+fcG++ p++i+++s + FUN_000984-T1 25 CKNRtVLKREGSFQSPNYPNHYPNGATCQWIIEIPHDIIaqkpfIKLEFKNFNVEMHLHCNYDKVLVYDGCKSNKTLMGSFCGNNTPSPIHATSGK 120 77777999*************************98754323456**************************************************** PP CUB 91 llikfvsdesvskkGFkaty 110 +l+kf+sd+ v++ GF+at+ FUN_000984-T1 121 MLVKFISDDFVTATGFNATF 140 ******************98 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.7 1.3 1.4e-11 1.6e-08 5 61 .] 268 324 .. 264 324 .. 0.97 2 ! 42.9 7.0 3.7e-14 4.2e-11 4 61 .] 315 373 .. 312 373 .. 0.94 3 ! 34.5 11.5 1.6e-11 1.7e-08 6 61 .] 366 421 .. 366 421 .. 0.98 4 ! 23.0 5.9 6.4e-08 7.1e-05 3 46 .. 411 454 .. 410 468 .. 0.88 5 ? -0.8 0.0 1.7 1.9e+03 2 24 .. 459 481 .. 458 485 .. 0.75 6 ? -3.1 0.0 9.1 1e+04 16 36 .. 827 847 .. 819 851 .. 0.75 Alignments for each domain: == domain 1 score: 34.7 bits; conditional E-value: 1.4e-11 LRR_8 5 sLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 s+dLs N+++++ + F++ nL L+LsnN++++ls+g+f+ + ++ LdL++N + FUN_000984-T1 268 SVDLSENYIENITASDFRSFWNLYDLYLSNNKIKRLSNGTFREAKDITLLDLTSNEI 324 789****************************************************87 PP == domain 2 score: 42.9 bits; conditional E-value: 3.7e-14 LRR_8 4 rsLdLssNrltslddgaFkglsn.LkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 + LdL+sN +++l+ ++F gl++ L+ LdLs+N+l+ l +++f++L+ L++L LsgN + FUN_000984-T1 315 TLLDLTSNEISHLEGDSFAGLEGtLTLLDLSENKLKNLARESFHNLRVLTYLLLSGNLI 373 679*****************9865999******************************87 PP == domain 3 score: 34.5 bits; conditional E-value: 1.6e-11 LRR_8 6 LdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 L Ls N ++sld +F++ls+L+ L Ls+N+lt l ++ f++ + L++L L+gN + FUN_000984-T1 366 LLLSGNLIKSLDSYTFSSLSSLELLVLSKNKLTNLTRELFHNIKTLKFLFLNGNLI 421 789***************************************************87 PP == domain 4 score: 23.0 bits; conditional E-value: 6.4e-08 LRR_8 3 LrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafs 46 L+ L L+ N ++sld +F +ls+L+ L+L +N l+ l+++a+ FUN_000984-T1 411 LKFLFLNGNLIKSLDSYTFGSLSSLELLNLADNPLQELNDHALY 454 77799***********************************9985 PP == domain 5 score: -0.8 bits; conditional E-value: 1.7 LRR_8 2 nLrsLdLssNrltslddgaFkgl 24 +L++++L ++ + ++ +aF+g FUN_000984-T1 459 SLHTIYLMNTIMERINLKAFEGQ 481 68888888888888888888874 PP == domain 6 score: -3.1 bits; conditional E-value: 9.1 LRR_8 16 lddgaFkglsnLkvLdLsnNl 36 l +++ ++ + ++L L++N FUN_000984-T1 827 LFPSWKQNAISKMHLMLGSNA 847 667777788888999999995 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.2 0.0 1.3e-16 1.4e-13 10 90 .] 158 230 .. 149 230 .. 0.92 Alignments for each domain: == domain 1 score: 51.2 bits; conditional E-value: 1.3e-16 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 v +G++ el c++sG p+p+v+W++ g el e++r+ v L ++nv+k+D+G+Y+c+a+ns g+++a+++LtV FUN_000984-T1 158 HFVLKGQKTELRCSASGLPTPNVTWTRLGVELIEGRRFAV--------LSLNNVTKADQGIYRCTASNSQGQKSATMNLTV 230 56889*****************************999976........6677***************************98 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.4 0.0 2.6e-16 2.9e-13 8 79 .] 156 230 .. 149 230 .. 0.87 Alignments for each domain: == domain 1 score: 50.4 bits; conditional E-value: 2.6e-16 Ig_2 8 ptv.vtegesvtLtCsasgnppakytwykdgkvlsssqn...fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 +++ v +g++ L+Csasg p++++tw++ g +l ++++ ++++nv+ d+G+Y+Cta+n ++g++s+++++tv FUN_000984-T1 156 ASHfVLKGQKTELRCSASGLPTPNVTWTRLGVELIEGRRfavLSLNNVTKADQGIYRCTASN-SQGQKSATMNLTV 230 4444889********************************76444599***************.5699999***998 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.1 0.0 1.6e-15 1.8e-12 11 78 .] 158 217 .. 149 217 .. 0.88 Alignments for each domain: == domain 1 score: 48.1 bits; conditional E-value: 1.6e-15 Ig_3 11 tvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 + v +g++ +L+C+a+g p+p++tW++ g el++g++ ++L+++nvt+ d+G Y+C+AsN FUN_000984-T1 158 HFVLKGQKTELRCSASGLPTPNVTWTRLGVELIEGRRF--------AVLSLNNVTKADQGIYRCTASN 217 33899*************************87775554........8********************9 PP >> LRR_5 BspA type Leucine rich repeat region (6 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.1 1.7e-05 0.019 21 123 .. 254 360 .. 250 364 .. 0.84 2 ! 34.3 2.4 2.4e-11 2.7e-08 3 123 .. 352 481 .. 350 485 .. 0.86 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.7e-05 LRR_5 21 sltsIgeyaFsnctslksitlpss.ltsigsyaFsnc.slesitips.sltsigeyaFsncsnlksitlpen.ltsigssaFsnc..slksitips 110 +ltsI + + ++ s++l+++ +++i + F + +l ++ +++ +++++++ +F++ + ++ ++l++n +++++ ++F++ +l+ +++++ FUN_000984-T1 254 NLTSIPSGTLRGF---VSVDLSENyIENITASDFRSFwNLYDLYLSNnKIKRLSNGTFREAKDITLLDLTSNeISHLEGDSFAGLegTLTLLDLSE 346 6777777777776...889998876999********99*******9768*******************9876699*******99547899999985 PP LRR_5 111 .svtkigeyaFsnc 123 +++++ +++F+n FUN_000984-T1 347 nKLKNLARESFHNL 360 48999999999885 PP == domain 2 score: 34.3 bits; conditional E-value: 2.4e-11 LRR_5 3 IgsyaFync.slesitipss.ltsIgeyaFsnctslksitlpss.ltsigsyaFsnc.slesitipss.ltsigeyaFsncsnlksitlpen.lts 92 + +++F+n l+ + ++ + ++s+++y+Fs+ +sl+ + l+++ lt++ ++ F n l+ + ++ + ++s+++y+F + s+l+ ++l n l++ FUN_000984-T1 352 LARESFHNLrVLTYLLLSGNlIKSLDSYTFSSLSSLELLVLSKNkLTNLTRELFHNIkTLKFLFLNGNlIKSLDSYTFGSLSSLELLNLADNpLQE 447 66789999889999999955389*****************98855************7788888886449*******************9888*** PP LRR_5 93 igssaF..sncslksitipssv.tkigeyaFsnc 123 ++++a +n+sl +i++ +++ ++i+ +aF++ FUN_000984-T1 448 LNDHALyiANSSLHTIYLMNTImERINLKAFEGQ 481 *****8335679*****99965279******987 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.3 0.1 4.4e-14 4.9e-11 2 81 .] 157 226 .. 156 226 .. 0.96 Alignments for each domain: == domain 1 score: 43.3 bits; conditional E-value: 4.4e-14 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatlst 81 ++ vl+G++ +L+Csas g p p+vtW + g ++ie+++ + l ++nvt+ d G Y+C+++n+ g++++++ FUN_000984-T1 157 SHFVLKGQKTELRCSAS-GLPTPNVTWTRLGVELIEGRR---------FAVLSLNNVTKADQGIYRCTASNSQGQKSATM 226 789**************.*******************88.........99************************999875 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.69 7.6e+02 12 40 .. 254 280 .. 250 286 .. 0.79 2 ! 14.2 0.6 4.9e-05 0.055 6 40 .. 269 304 .. 267 309 .. 0.88 3 ! 13.0 1.6 0.00012 0.13 6 43 .. 293 328 .. 288 329 .. 0.88 4 ! 7.1 1.6 0.0084 9.4 3 28 .. 339 363 .. 337 364 .. 0.89 5 ! 17.0 6.1 6.6e-06 0.0073 3 39 .. 363 400 .. 361 404 .. 0.88 6 ! 20.5 4.9 5.4e-07 0.0006 2 41 .. 410 450 .. 409 453 .. 0.86 7 ? -1.8 0.0 5.4 6e+03 23 35 .. 458 469 .. 450 476 .. 0.70 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.69 LRR_4 12 ritdidplskLpnLetLdLsgNnkitdls 40 ++t+i++ L ++dLs N i++++ FUN_000984-T1 254 NLTSIPSGT-LRGFVSVDLSEN-YIENIT 280 488888866.9999999**888.999996 PP == domain 2 score: 14.2 bits; conditional E-value: 4.9e-05 LRR_4 6 LdLsnNritdidp..lskLpnLetLdLsgNnkitdls 40 dLs N i++i ++++ nL L+L +Nnki+ ls FUN_000984-T1 269 VDLSENYIENITAsdFRSFWNLYDLYL-SNNKIKRLS 304 699*9********77779*********.777**9986 PP == domain 3 score: 13.0 bits; conditional E-value: 0.00012 LRR_4 6 LdLsnNritdidp..lskLpnLetLdLsgNnkitdlsdLk 43 L+LsnN+i+++++ ++ ++ + LdL++N ++s+L+ FUN_000984-T1 293 LYLSNNKIKRLSNgtFREAKDITLLDLTSN----EISHLE 328 9************98777*********999....888875 PP == domain 4 score: 7.1 bits; conditional E-value: 0.0084 LRR_4 3 LetLdLsnNritdidplskLpnLetL 28 L+ LdLs N+++++ s ++nL++L FUN_000984-T1 339 LTLLDLSENKLKNLARES-FHNLRVL 363 899**********77777.*****99 PP == domain 5 score: 17.0 bits; conditional E-value: 6.6e-06 LRR_4 3 LetLdLsnNritdidp..lskLpnLetLdLsgNnkitdl 39 L++L Ls+N i+++d+ +s+L +Le L Ls N k+t+l FUN_000984-T1 363 LTYLLLSGNLIKSLDSytFSSLSSLELLVLSKN-KLTNL 400 99**************77778*********666.88887 PP == domain 6 score: 20.5 bits; conditional E-value: 5.4e-07 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitdlsd 41 L+ L L++N i+++d+ +++L +Le L+L++N ++++l+d FUN_000984-T1 410 TLKFLFLNGNLIKSLDSytFGSLSSLELLNLADN-PLQELND 450 7****************76669*********777.7777765 PP == domain 7 score: -1.8 bits; conditional E-value: 5.4 LRR_4 23 pnLetLdLsgNnk 35 +L+t++L N+ FUN_000984-T1 458 SSLHTIYL-MNTI 469 57888888.6644 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.4 2.7e-05 0.03 40 125 .. 262 349 .. 253 366 .. 0.84 2 ! 18.3 3.4 1.7e-06 0.0019 49 138 .. 368 458 .. 363 477 .. 0.89 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.7e-05 LRR_9 40 tldqfdtidlsdneirkld..gfPllkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslk.kltslsllrnpv 125 tl f ++dls+n i ++ +f + l l+l nn+i r+++g + + ++ l lt+n++++l d +a l+ lt l l +n + FUN_000984-T1 262 TLRGFVSVDLSENYIENITasDFRSFWNLYDLYLSNNKIKRLSNGTFREAKDITLLDLTSNEISHLEG-DSFAGLEgTLTLLDLSENKL 349 778899*********9985226888999*************************************987.88998873577777777765 PP == domain 2 score: 18.3 bits; conditional E-value: 1.7e-06 LRR_9 49 lsdneirkldgfPl..lkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslkkltslsllrnpvtnkedyrlyviyk 138 ls n i+ ld++ + l l+ l+l +n++++++ +l + + +l+ l l +n +++l + sl++l+ l l +np+ + +d+ ly+++ FUN_000984-T1 368 LSGNLIKSLDSYTFssLSSLELLVLSKNKLTNLTRELFHNIKTLKFLFLNGNLIKSLDS-YTFGSLSSLELLNLADNPLQELNDHALYIANS 458 79999*****86543399**************************************988.889**********************9999874 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.18 2e+02 9 35 .. 161 184 .. 156 189 .. 0.88 2 ! 19.5 0.0 1.1e-06 0.0012 72 108 .. 195 230 .. 187 231 .. 0.92 3 ? -1.5 0.0 3.7 4.1e+03 15 39 .. 823 847 .. 822 886 .. 0.70 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.18 V-set 9 aeGesvtLtCslssseseasqsvyWyr 35 G++ +L+Cs s ++ v+W+r FUN_000984-T1 161 LKGQKTELRCSASGL---PTPNVTWTR 184 579*******99999...9******98 PP == domain 2 score: 19.5 bits; conditional E-value: 1.1e-06 V-set 72 dfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + l ++n+t +D+G+Y C ++++++++++++LtV FUN_000984-T1 195 FAVLSLNNVTKADQGIYRCT-ASNSQGQKSATMNLTV 230 57899***************.9**************9 PP == domain 3 score: -1.5 bits; conditional E-value: 3.7 V-set 15 tLtCslssseseasqsvyWyrqppg 39 L+C ++s++++a+ +++ + +++ FUN_000984-T1 823 PLHCLFPSWKQNAISKMHLMLGSNA 847 599*999999999999988887765 PP >> LRRNT Leucine rich repeat N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 1.3 3.3e-08 3.7e-05 1 25 [. 232 260 .. 232 261 .. 0.97 2 ? -1.9 0.1 3.6 4e+03 5 13 .. 607 618 .. 606 619 .. 0.73 3 ? -0.9 0.1 1.7 1.9e+03 1 9 [. 687 695 .. 687 701 .. 0.85 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 3.3e-08 LRRNT 1 aCPvpChCs....atvVnCsdrgLtavPr 25 aCP +C+Cs +++V+C + +Lt++P+ FUN_000984-T1 232 ACPDNCVCSfllyDLTVDCLRANLTSIPS 260 7***************************8 PP == domain 2 score: -1.9 bits; conditional E-value: 3.6 LRRNT 5 pChCs...atvV 13 C+C ++++ FUN_000984-T1 607 ACKCIdgfHRTM 618 7***97777665 PP == domain 3 score: -0.9 bits; conditional E-value: 1.7 LRRNT 1 aCPvpChCs 9 +CP+ C FUN_000984-T1 687 QCPRAKSCE 695 7*******7 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.2 5.2e-06 0.0058 6 69 .. 168 238 .. 163 239 .. 0.77 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 5.2e-06 Ig_4 6 LtCnsss...keitwlkdgkeikeskek.tldlgksiedprglYqCk..eeekkkssslqvyyRmC.qNCv 69 L+C+ s ++tw + g e e ++ l+l+++++ ++g+Y+C+ +++ +ks ++ + + C +NCv FUN_000984-T1 168 LRCSASGlptPNVTWTRLGVELIEGRRFaVLSLNNVTKADQGIYRCTasNSQGQKSATMNLTVEACpDNCV 238 666443322257999987666555554449*****************98778999***********77998 PP >> Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.5 0.011 13 13 35 .. 525 555 .. 524 562 .. 0.72 2 ! 12.7 3.8 0.00011 0.12 9 38 .. 566 600 .. 555 610 .. 0.83 3 ? 1.6 1.8 0.32 3.6e+02 22 43 .. 617 638 .. 601 642 .. 0.74 4 ! 8.8 0.8 0.0018 1.9 11 35 .. 711 732 .. 706 736 .. 0.88 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.011 Ephrin_rec_like 13 pCprgtYqp........eegqlsClaCPlgt 35 pCp gt+ p + ++C++CP+g+ FUN_000984-T1 525 PCPTGTFVPplksfnldIALESKCIPCPPGG 555 7888888887776766556678899999765 PP == domain 2 score: 12.7 bits; conditional E-value: 0.00011 Ephrin_rec_like 9 etCipCprgtYqp.....eegqlsClaCPlgtttk 38 + C pC +gtY p + l C+ CP+gt+t+ FUN_000984-T1 566 QNCFPCNNGTYVPperapGKSVLHCIVCPTGTRTD 600 45***********77765566789********998 PP == domain 3 score: 1.6 bits; conditional E-value: 0.32 Ephrin_rec_like 22 eegqlsClaCPlgtttkstgat 43 + +++ C++CP+++ +++ FUN_000984-T1 617 TMRFGPCEKCPSTGLNCVDESV 638 567788*****98766666655 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0018 Ephrin_rec_like 11 CipCprgtYqpeegqlsClaCPlgt 35 C+ C+ ++Y+ +l+C+ CP+gt FUN_000984-T1 711 CEVCEGNYYKR---ALACKLCPSGT 732 99*******85...799*****997 PP >> TRP Transient receptor potential (TRP) ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 1.5e-05 0.017 268 409 .. 1026 1168 .. 1012 1178 .. 0.86 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.5e-05 TRP 268 lLysdkkvlnkyGflyvqyrasrywffvpllvylfvkalfialaqgsgkvQvialliiEllylvllivlrPyedkrtnvlnilisvvnvlnail 361 L s+++ l +fly++y+++++++ ++ ++ +v + i l ++ + v + ++ l+ v++++ +P d l+ + +v +ln+ + FUN_000984-T1 1026 QLNSESELLSGMSFLYENYNEDAWYWELVEVIRKLVLTCGIILIGRESRTYVGLASLCSGLFAVAFAFRKPIRDDFEDKLQLTSLLVIFLNLGI 1119 677888999999***************************999999999999999999*************************999999999987 PP TRP 362 llvF.seefglpeivktvvGvvlfvvnaaltlvlliliivnaiiallsk 409 +++ + + ++p v +v l+ + + + vl+il++v+ ++a+l + FUN_000984-T1 1120 GVILkISTESVPSDVDKYVDCLLVNILVVGVNVLVILLVVGRFLAVLIH 1168 6666266778999999999999999999999999999999988887754 PP >> DUF7630 Domain of unknown function (DUF7630) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 1.8 0.17 1.9e+02 27 45 .] 609 626 .. 599 626 .. 0.88 2 ! 16.9 11.3 6.3e-06 0.007 3 42 .. 687 728 .. 686 730 .. 0.91 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.17 DUF7630 27 eCkkGYtnnfskgslCtkC 45 +C +G+ +++ + C+kC FUN_000984-T1 609 KCIDGFHRTMR-FGPCEKC 626 8*******998.6****** PP == domain 2 score: 16.9 bits; conditional E-value: 6.3e-06 DUF7630 3 kCPiegaClg..kgkCaegmtgyLCaeCkkGYtnnfskgslC 42 +CP+ ++C g ++kCa+g+tg LC C+ Y++ + +lC FUN_000984-T1 687 QCPRAKSCEGglESKCAKGYTGPLCEVCEGNYYKRALACKLC 728 8*********999********************988876666 PP >> TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 1.3 1.4e+03 5 22 .. 514 531 .. 514 534 .. 0.78 2 ? 6.9 4.3 0.0076 8.5 11 36 .. 545 575 .. 542 579 .. 0.77 3 ? 3.6 2.8 0.08 89 12 39 .. 566 600 .. 562 602 .. 0.70 4 ? 0.3 0.1 0.88 9.8e+02 28 34 .. 622 628 .. 613 630 .. 0.82 5 ? 12.4 0.3 0.00014 0.16 13 36 .. 710 732 .. 704 735 .. 0.93 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.3 TNFR_ELAPOR1_6th 5 GmeknnsstCefCpkgsy 22 G+++ n + +Cp+g++ FUN_000984-T1 514 GFARGNRTYRVPCPTGTF 531 677777777789999988 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0076 TNFR_ELAPOR1_6th 11 sstCefCpkg.sySdGt....eeCkkCPagT 36 +s+C +Cp+g +ySdG ++C C gT FUN_000984-T1 545 ESKCIPCPPGgFYSDGIaivgQNCFPCNNGT 575 689****985389**9633446888888877 PP == domain 3 score: 3.6 bits; conditional E-value: 0.08 TNFR_ELAPOR1_6th 12 stCefCpkgsySdGte.......eCkkCPagTePn 39 ++C +C++g+y ++ C CP gT+ + FUN_000984-T1 566 QNCFPCNNGTYVPPERapgksvlHCIVCPTGTRTD 600 68999999999765432222233699999999876 PP == domain 4 score: 0.3 bits; conditional E-value: 0.88 TNFR_ELAPOR1_6th 28 eCkkCPa 34 +C+kCP FUN_000984-T1 622 PCEKCPS 628 6999986 PP == domain 5 score: 12.4 bits; conditional E-value: 0.00014 TNFR_ELAPOR1_6th 13 tCefCpkgsySdGteeCkkCPagT 36 Ce+C+ ++y +Ck CP gT FUN_000984-T1 710 LCEVCEGNYYKRAL-ACKLCPSGT 732 5*************.********9 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.0048 5.3 22 42 .. 163 183 .. 155 192 .. 0.88 2 ? 4.2 0.0 0.057 64 91 127 .. 195 231 .. 184 234 .. 0.73 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0048 Ig_VEGFR-1-like_5th 22 dqrhkltctafgipmpnitwf 42 q+ +l c+a g+p pn+tw FUN_000984-T1 163 GQKTELRCSASGLPTPNVTWT 183 58999***************6 PP == domain 2 score: 4.2 bits; conditional E-value: 0.057 Ig_VEGFR-1-like_5th 91 rtistlvvktanvsgvysctarnelgnrtmripfyvd 127 ++ +l t g+y cta n g+++ + + v+ FUN_000984-T1 195 FAVLSLNNVTKADQGIYRCTASNSQGQKSATMNLTVE 231 45555556677778************99887777665 PP >> CDCP1_CUB_6 CDCP1 CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.00017 0.19 17 50 .. 36 69 .. 28 88 .. 0.85 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00017 CDCP1_CUB_6 17 lLatPnwpeGmkpsstvsWivsvpskqkaelkfl 50 +++Pn+p+ ++ +t +Wi+++p++ a+ f FUN_000984-T1 36 SFQSPNYPNHYPNGATCQWIIEIPHDIIAQKPFI 69 579*********************9988875554 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.0005 0.56 14 42 .. 163 196 .. 146 227 .. 0.75 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0005 C2-set_2 14 ekevvatCvsaggkPapritWlldgkel......e 42 +++ ++C sa+g P+p++tW + g el FUN_000984-T1 163 GQKTELRC-SASGLPTPNVTWTRLGVELiegrrfA 196 668999**.99***********9999985444443 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.78 8.7e+02 4 22 .. 268 286 .. 266 287 .. 0.85 2 ? 4.6 0.2 0.072 80 1 16 [. 289 304 .. 289 310 .. 0.76 3 ? 3.5 0.1 0.17 1.9e+02 3 23 .] 315 335 .. 313 335 .. 0.87 4 ? 6.1 0.5 0.024 26 2 23 .] 339 360 .. 338 360 .. 0.90 5 ? 4.2 0.3 0.1 1.1e+02 2 23 .] 363 384 .. 362 384 .. 0.89 6 ? 3.7 0.7 0.15 1.7e+02 1 22 [. 386 407 .. 386 408 .. 0.85 7 ? 2.9 0.3 0.28 3.1e+02 2 23 .] 411 432 .. 410 432 .. 0.88 8 ? 4.0 0.2 0.12 1.3e+02 1 16 [. 434 449 .. 434 454 .. 0.81 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.78 LRR_1 4 eLdLsnNnlsgllpeslgn 22 ++dLs N ++ + +++++ FUN_000984-T1 268 SVDLSENYIENITASDFRS 286 68*******9999888876 PP == domain 2 score: 4.6 bits; conditional E-value: 0.072 LRR_1 1 nLeeLdLsnNnlsgll 16 nL L+LsnN++ l+ FUN_000984-T1 289 NLYDLYLSNNKIKRLS 304 7889********6554 PP == domain 3 score: 3.5 bits; conditional E-value: 0.17 LRR_1 3 eeLdLsnNnlsgllpeslgnl 23 + LdL +N +s+l +s+++l FUN_000984-T1 315 TLLDLTSNEISHLEGDSFAGL 335 77*********9999999876 PP == domain 4 score: 6.1 bits; conditional E-value: 0.024 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L+ LdLs N+l l es+ nl FUN_000984-T1 339 LTLLDLSENKLKNLARESFHNL 360 899********99999999887 PP == domain 5 score: 4.2 bits; conditional E-value: 0.1 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L++L Ls+N + +l++ ++++l FUN_000984-T1 363 LTYLLLSGNLIKSLDSYTFSSL 384 89*********98998888876 PP == domain 6 score: 3.7 bits; conditional E-value: 0.15 LRR_1 1 nLeeLdLsnNnlsgllpeslgn 22 +Le L Ls N+l+ l e + n FUN_000984-T1 386 SLELLVLSKNKLTNLTRELFHN 407 799*********9888877765 PP == domain 7 score: 2.9 bits; conditional E-value: 0.28 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L+ L L++N + +l++ ++g+l FUN_000984-T1 411 LKFLFLNGNLIKSLDSYTFGSL 432 99*********98999988876 PP == domain 8 score: 4.0 bits; conditional E-value: 0.12 LRR_1 1 nLeeLdLsnNnlsgll 16 +Le L+L++N+l +l FUN_000984-T1 434 SLELLNLADNPLQELN 449 79**********7655 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.00023 0.26 3 33 .. 151 183 .. 149 185 .. 0.77 2 ? 0.8 0.1 0.55 6.1e+02 83 112 .. 205 233 .. 188 243 .. 0.74 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00023 Ig_PDGFR_d4 3 ilelsdsh..assgeqtvtCvaeGmPqPeveWf 33 i++++ sh + ++ ++C a G+P+P+v+W FUN_000984-T1 151 IVDMTASHfvLKGQKTELRCSASGLPTPNVTWT 183 666776662245667789**************6 PP == domain 2 score: 0.8 bits; conditional E-value: 0.55 Ig_PDGFR_d4 83 kveetlavrCeaknelgadsrevkLvsstl 112 k ++ rC+a+n+ g++s ++L ++ FUN_000984-T1 205 KADQG-IYRCTASNSQGQKSATMNLTVEAC 233 44443.46***********99999977665 PP >> DUF4381 Domain of unknown function (DUF4381) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.4 0.14 1.5e+02 20 46 .. 731 762 .. 728 779 .. 0.55 2 ? 6.8 0.1 0.0096 11 30 58 .. 955 980 .. 945 993 .. 0.49 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.14 DUF4381 20 Gwwlll.alll.llllvlalwllr...rrrrk 46 G w+++ + ll +++lvl++ l++ rr+ FUN_000984-T1 731 GTWVIVqLSLLgVAVLVLIIILIWsgrRRKSA 762 56766666666655555555444411044433 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0096 DUF4381 30 llllvlalwllrrrrrkrrealreLaalr 58 ++l +la+w+l+rrrr + l+ L++lr FUN_000984-T1 955 VVLPGLAFWALWRRRR---QQLSRLRKLR 980 4444555555544443...3444444444 PP >> CcmD Heme exporter protein D (CcmD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.2 0.0021 2.3 12 32 .. 742 762 .. 741 770 .. 0.88 2 ? 8.7 0.9 0.0022 2.5 16 39 .. 955 979 .. 946 982 .. 0.68 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0021 CcmD 12 gvtllvLaglilwsllqrrrl 32 gv++lvL+++++ws ++r+ + FUN_000984-T1 742 GVAVLVLIIILIWSGRRRKSA 762 89****************976 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0022 CcmD 16 lvLaglilwsllqrrr.llrelrrl 39 +vL gl +w l++rrr +l +lr+l FUN_000984-T1 955 VVLPGLAFWALWRRRRqQLSRLRKL 979 7788888888877665156666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1262 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1385 (0.054218); expected 510.9 (0.02) Passed bias filter: 795 (0.0311216); expected 510.9 (0.02) Passed Vit filter: 96 (0.00375807); expected 25.5 (0.001) Passed Fwd filter: 29 (0.00113525); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 23 [number of targets reported over threshold] # CPU time: 0.52u 0.44s 00:00:00.96 Elapsed: 00:00:00.44 # Mc/sec: 11655.88 // Query: FUN_000985-T1 [L=886] Description: FUN_000985 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00043 19.7 0.2 0.0013 18.1 0.2 1.7 1 TRP Transient receptor potential (TRP) ion chan 0.00054 20.2 25.0 0.11 12.8 4.0 4.9 4 Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B rec 0.00083 19.9 11.3 0.0047 17.5 11.3 2.3 1 DUF7630 Domain of unknown function (DUF7630) ------ inclusion threshold ------ 0.012 16.0 22.9 0.11 13.0 0.3 5.4 5 TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like 0.02 14.9 1.7 0.93 9.5 0.1 2.4 2 Stevor Subtelomeric Variable Open Reading frame 0.23 12.6 6.4 5.7 8.2 0.0 4.1 4 EphA2_TM Ephrin type-A receptor 2 transmembrane doma 0.51 10.6 4.3 0.66 10.2 0.0 2.3 2 FAM176 FAM176 family 0.8 10.5 6.2 5.8 7.7 0.0 3.5 4 DUF4381 Domain of unknown function (DUF4381) 4.5 7.9 12.7 1.6 9.4 0.2 3.3 3 CcmD Heme exporter protein D (CcmD) Domain annotation for each model (and alignments): >> TRP Transient receptor potential (TRP) ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.2 4.7e-07 0.0013 274 409 .. 640 776 .. 634 787 .. 0.89 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 4.7e-07 TRP 274 kvlnkyGflyvqyrasrywffvpllvylfvkalfialaqgsgkvQvialliiEllylvllivlrPyedkrtnvlnilisvvnvlnailllvF.see 368 + l +fly++y+++++++ ++ ++ ++ + i l ++ + v + i+ l+ +++++ +P dk l+ + +v +ln+ + +++ +++ FUN_000985-T1 640 ELLSGMSFLYENYNEDAWYWELVEVIRKLLLTCGIILIGRESRTYVGLASICSGLFAIAFAFRKPIRDKFEDKLQLTSLLVIFLNLGIGVILkIPK 735 5666679*****************999999999999999999**********************************99999999998766653799 PP TRP 369 fglpeivktvvGvvlfvvnaaltlvlliliivnaiiallsk 409 ++p v ++v l+ + + + vl+il++v+ ++a+l + FUN_000985-T1 736 ESVPSDVDQYVDTLLVNILVVGANVLVILLVVGRYLAVLIH 776 99**********99999999999999999999999888754 PP >> Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.6 0.0031 8.9 13 35 .. 134 164 .. 132 171 .. 0.73 2 ! 12.8 4.0 3.8e-05 0.11 10 38 .. 176 209 .. 170 219 .. 0.84 3 ? 2.8 1.6 0.05 1.4e+02 19 43 .. 223 247 .. 215 251 .. 0.74 4 ! 9.4 0.8 0.00046 1.3 11 35 .. 320 341 .. 315 345 .. 0.88 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0031 Ephrin_rec_like 13 pCprgtYqp........eegqlsClaCPlgt 35 pCp gt+ p + ++C++CP+g+ FUN_000985-T1 134 PCPTGTFVPplksfnldIALESKCIPCPPGG 164 7888888887777766556678899999775 PP == domain 2 score: 12.8 bits; conditional E-value: 3.8e-05 Ephrin_rec_like 10 tCipCprgtYqp.....eegqlsClaCPlgtttk 38 C pC +gtY p + l C+ CP+gt+t+ FUN_000985-T1 176 NCFPCNNGTYVPperapGKSVLHCIVCPTGTRTD 209 5***********77765566789********998 PP == domain 3 score: 2.8 bits; conditional E-value: 0.05 Ephrin_rec_like 19 YqpeegqlsClaCPlgtttkstgat 43 + + +++ C++CP+++ +++ FUN_000985-T1 223 FHRTMRFGPCENCPSTGLNCVDESV 247 556677889*****98876666665 PP == domain 4 score: 9.4 bits; conditional E-value: 0.00046 Ephrin_rec_like 11 CipCprgtYqpeegqlsClaCPlgt 35 C+ C+ ++Y+ +l+C+ CP+gt FUN_000985-T1 320 CEVCEGNYYKR---ALACKLCPSGT 341 99*******85...799*****997 PP >> DUF7630 Domain of unknown function (DUF7630) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 11.3 1.6e-06 0.0047 3 42 .. 296 337 .. 295 339 .. 0.91 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1.6e-06 DUF7630 3 kCPiegaClg..kgkCaegmtgyLCaeCkkGYtnnfskgslC 42 +CP+ ++C g ++kCa+g+tg LC C+ Y++ + +lC FUN_000985-T1 296 QCPRAKSCEGglESKCAKGYTGPLCEVCEGNYYKRALACKLC 337 8*********999********************988876666 PP >> TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.34 9.6e+02 5 22 .. 123 140 .. 123 143 .. 0.78 2 ? 7.2 4.6 0.0024 6.9 11 36 .. 154 184 .. 151 188 .. 0.77 3 ? 3.5 3.4 0.033 95 12 39 .. 175 209 .. 173 211 .. 0.68 4 ? -0.4 0.4 0.56 1.6e+03 28 34 .. 231 237 .. 228 239 .. 0.77 5 ? 13.0 0.3 3.8e-05 0.11 13 36 .. 319 341 .. 313 344 .. 0.93 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.34 TNFR_ELAPOR1_6th 5 GmeknnsstCefCpkgsy 22 G+++ n + +Cp+g++ FUN_000985-T1 123 GFARGNRTYRVPCPTGTF 140 677777777789999988 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0024 TNFR_ELAPOR1_6th 11 sstCefCpkg.sySdGt....eeCkkCPagT 36 +s+C +Cp+g +ySdG ++C C gT FUN_000985-T1 154 ESKCIPCPPGgFYSDGIaivgQNCFPCNNGT 184 689****985389**9633446888888877 PP == domain 3 score: 3.5 bits; conditional E-value: 0.033 TNFR_ELAPOR1_6th 12 stCefCpkgsySdGte.......eCkkCPagTePn 39 ++C +C++g+y ++ C CP gT+ + FUN_000985-T1 175 QNCFPCNNGTYVPPERapgksvlHCIVCPTGTRTD 209 57999999999765432222233699999999876 PP == domain 4 score: -0.4 bits; conditional E-value: 0.56 TNFR_ELAPOR1_6th 28 eCkkCPa 34 +C++CP FUN_000985-T1 231 PCENCPS 237 6888885 PP == domain 5 score: 13.0 bits; conditional E-value: 3.8e-05 TNFR_ELAPOR1_6th 13 tCefCpkgsySdGteeCkkCPagT 36 Ce+C+ ++y +Ck CP gT FUN_000985-T1 319 LCEVCEGNYYKRAL-ACKLCPSGT 341 5*************.********9 PP >> Stevor Subtelomeric Variable Open Reading frame # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.1 0.00033 0.93 236 263 .. 342 370 .. 321 377 .. 0.82 2 ? 4.3 0.1 0.013 36 231 269 .. 550 588 .. 491 592 .. 0.76 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00033 Stevor 236 ygiaalvLlilav.vliiLYiWlyrRRkn 263 + i+ l Ll +av vlii+ iW rRRk+ FUN_000985-T1 342 WVIVQLSLLGVAVlVLIIILIWSGRRRKS 370 5677787886665389***********97 PP == domain 2 score: 4.3 bits; conditional E-value: 0.013 Stevor 231 safepygiaalvLlilavvliiLYiWlyrRRknswkhec 269 ++ ++ aa +++ vl+ L +W +rR + s k ++ FUN_000985-T1 550 NFVKLFAFAASSYIVVLPVLVFLALWRRRRQQLSRKRKV 588 556667889999999999********9999999988765 PP >> EphA2_TM Ephrin type-A receptor 2 transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.2 0.024 68 4 27 .. 348 371 .. 343 381 .. 0.53 2 ? -1.2 0.0 1.7 4.9e+03 8 33 .. 460 487 .. 451 501 .. 0.46 3 ? 8.2 0.0 0.002 5.7 4 36 .. 558 590 .. 555 606 .. 0.67 4 ? -2.1 0.4 3.2 9.1e+03 2 13 .. 762 773 .. 753 790 .. 0.45 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.024 EphA2_TM 4 avagglvllvvvvvvlivrrrrkk 27 +++g+ vl++++++++ rrr++ FUN_000985-T1 348 SLLGVAVLVLIIILIWSGRRRKSA 371 445555555555555554543332 PP == domain 2 score: -1.2 bits; conditional E-value: 1.7 EphA2_TM 8 glvllvvvvvvlivrr..rrkkrskaeq 33 +++l+++ + l++ r +++++sk++ FUN_000985-T1 460 LFALISFWIRKLFLLRniNKEQSSKRRI 487 2222222233344444454444444444 PP == domain 3 score: 8.2 bits; conditional E-value: 0.002 EphA2_TM 4 avagglvllvvvvvvlivrrrrkkrskaeqdye 36 a+ +v+l v+v+++++rrrr++ s++++ + FUN_000985-T1 558 AASSYIVVLPVLVFLALWRRRRQQLSRKRKVRD 590 556667788888889999997777666665542 PP == domain 4 score: -2.1 bits; conditional E-value: 3.2 EphA2_TM 2 vgavagglvllv 13 v+ +++g +l v FUN_000985-T1 762 VILLVVGRYLAV 773 222223333333 PP >> FAM176 FAM176 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.00023 0.66 35 89 .. 563 630 .. 554 656 .. 0.66 2 ? 0.0 1.7 0.32 9.2e+02 68 94 .. 846 872 .. 828 885 .. 0.46 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00023 FAM176 35 vltLcllViriscrkdlkklakkkkelkeeseed.............eedseeeeeeeeedsseseik 89 ++ L +lV+ +r+++++l++k+k ++ +++e+ +e +ee++e++++d+ +++ + FUN_000985-T1 563 IVVLPVLVFLALWRRRRQQLSRKRKVRDVKQKEEnnpvdpefgkhgnTEAAEENNEDTHDDEGNEDNP 630 788999************99999988888887776788888887665222232222222222222222 PP == domain 2 score: 0.0 bits; conditional E-value: 0.32 FAM176 68 deedseeeeeeeeedsseseikdelte 94 + +d++ ee+++e +++++++ + ++ FUN_000985-T1 846 EPDDDNAEEDKKEREAKKRHVIFKYKN 872 222333333334444444433333322 PP >> DUF4381 Domain of unknown function (DUF4381) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 1.1 3.3e+03 42 88 .. 41 92 .. 29 95 .. 0.69 2 ? 3.7 0.4 0.036 1e+02 20 46 .. 340 371 .. 337 388 .. 0.55 3 ? -2.8 0.0 3.6 1e+04 15 43 .. 448 475 .. 443 492 .. 0.44 4 ? 7.7 0.0 0.002 5.8 26 58 .. 563 595 .. 555 604 .. 0.77 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.1 DUF4381 42 rrrrk.rrealreLaalr....adeadaaellaelselLkrvalaafpreqv 88 rr + r a L++l+ + ++++ +++ +++++ r+ l af+ +q+ FUN_000985-T1 41 RRSCDvRNLADNPLQELNdhafYIANSSLHTIYLMNTIMERINLKAFEGQQL 92 33333444455555555544499999999999999****9999999987775 PP == domain 2 score: 3.7 bits; conditional E-value: 0.036 DUF4381 20 Gwwlll.alll.llllvlalwllr...rrrrk 46 G w+++ + ll +++lvl++ l++ rr+ FUN_000985-T1 340 GTWVIVqLSLLgVAVLVLIIILIWsgrRRKSA 371 56776666666655555555444411044433 PP == domain 3 score: -2.8 bits; conditional E-value: 3.6 DUF4381 15 wPpapGwwlllalllllllvlalwllrrr 43 +++ +G + + +l++l+ +++ l+ r FUN_000985-T1 448 MYLMLGSNASV-ILFALISFWIRKLFLLR 475 55555533222.33444444444333322 PP == domain 4 score: 7.7 bits; conditional E-value: 0.002 DUF4381 26 alllllllvlalwllrrrrrkrrealreLaalr 58 +++l +l++lalw++rr++ +r++ r +++ + FUN_000985-T1 563 IVVLPVLVFLALWRRRRQQLSRKRKVRDVKQKE 595 466688999999999988888998888887766 PP >> CcmD Heme exporter protein D (CcmD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.2 0.00056 1.6 12 32 .. 351 371 .. 350 379 .. 0.88 2 ? 6.7 0.4 0.0038 11 10 33 .. 561 581 .. 556 595 .. 0.61 3 ? -3.8 1.6 7.4 2.1e+04 16 33 .. 754 771 .. 753 774 .. 0.71 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00056 CcmD 12 gvtllvLaglilwsllqrrrl 32 gv++lvL+++++ws ++r+ + FUN_000985-T1 351 GVAVLVLIIILIWSGRRRKSA 371 89****************976 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0038 CcmD 10 aYgvtllvLaglilwsllqrrrll 33 +Y v+l vL++l l ++rrr++ FUN_000985-T1 561 SYIVVLPVLVFLAL---WRRRRQQ 581 66666666655555...4444442 PP == domain 3 score: -3.8 bits; conditional E-value: 7.4 CcmD 16 lvLaglilwsllqrrrll 33 lv+++++l +ll r+l FUN_000985-T1 754 LVVGANVLVILLVVGRYL 771 788888888887666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (886 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1329 (0.0520258); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.43u 0.40s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 8324.21 // Query: FUN_000986-T1 [L=436] Description: FUN_000986 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-26 91.6 0.0 1e-25 90.7 0.0 1.5 1 CUB CUB domain 2.1e-24 85.5 22.2 9.2e-10 38.6 1.7 2.9 4 LRR_8 Leucine rich repeat 2.3e-14 53.8 0.0 5.1e-14 52.7 0.0 1.5 1 Ig_2 Immunoglobulin domain 6.6e-14 52.2 0.0 1.9e-13 50.8 0.0 1.8 1 I-set Immunoglobulin I-set domain 6.6e-13 49.4 0.0 1.7e-12 48.1 0.0 1.8 1 Ig_3 Immunoglobulin domain 4.9e-11 43.3 0.0 9.4e-11 42.4 0.0 1.5 1 ig Immunoglobulin domain 3.6e-06 26.9 1.3 1.1e-05 25.4 1.3 1.8 1 LRRNT Leucine rich repeat N-terminal domain 5.3e-06 27.1 0.2 0.00032 21.3 0.0 2.4 2 V-set Immunoglobulin V-set domain 0.00041 20.4 9.2 7.2 7.8 0.5 5.0 4 LRR_1 Leucine Rich Repeat 0.0016 19.4 0.2 0.0035 18.4 0.2 1.6 1 Ig_4 T-cell surface glycoprotein CD3 delta ch 0.0026 17.8 0.5 0.0047 17.0 0.5 1.4 1 LRR_9 Leucine-rich repeat 0.0031 18.0 0.2 0.12 12.8 0.0 2.4 2 Ig_PDGFR_d4 Platelet-derived growth factor receptor 0.0037 18.1 0.1 0.009 16.9 0.1 1.6 1 Ig_5 Ig-like domain on T-cell surface glycopr 0.0052 17.5 18.8 0.025 15.3 1.2 3.9 4 LRR_4 Leucine Rich repeats (2 copies) ------ inclusion threshold ------ 0.027 15.1 0.1 10 6.8 0.0 2.4 2 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.059 13.4 0.0 0.12 12.5 0.0 1.4 1 CDCP1_CUB_6 CDCP1 CUB domain 0.15 12.6 0.0 0.41 11.2 0.0 1.7 1 C2-set_2 CD80-like C2-set immunoglobulin domain 0.22 12.0 0.0 0.47 10.9 0.0 1.6 1 Izumo-Ig Izumo-like Immunoglobulin domain 0.27 11.5 1.4 0.83 9.9 1.4 1.9 1 CUB_2 CUB-like domain Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.7 0.0 7.5e-29 1e-25 1 110 [] 25 136 .. 25 136 .. 0.92 Alignments for each domain: == domain 1 score: 90.7 bits; conditional E-value: 7.5e-29 CUB 1 Cgge.ltessgsisspnypkeYeenkeCvweirvekgks.....vklkfedfeleeeeecaydyvevrdgeeasskllgkfcGsekpediksssnq 90 C++ + +++gs++spnyp++Y++ ++C+w i+++++ ++l+f++f++e + +c+yd v v+dg+ l+++fcG++ p++i+++s + FUN_000986-T1 25 CKNPtVLKREGSFQSPNYPNHYPNGATCQWIIEIPYDIIaqkpfITLEFKNFNVEMHWRCNYDRVLVYDGNI----LMASFCGHNTPSPIHATSGK 116 666668999************************98754223456**************************99....99****************** PP CUB 91 llikfvsdesvskkGFkaty 110 +l+kf+sd+ v++ GF+at+ FUN_000986-T1 117 MLVKFISDDVVTATGFNATF 136 ******************98 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.056 75 13 46 .. 251 281 .. 240 284 .. 0.72 2 ! 36.5 1.3 3.1e-12 4.1e-09 5 61 .] 264 320 .. 260 320 .. 0.97 3 ! 38.6 1.7 6.8e-13 9.2e-10 2 49 .. 285 332 .. 285 337 .. 0.96 4 ! 36.8 4.5 2.6e-12 3.5e-09 4 55 .. 311 363 .. 308 368 .. 0.91 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.056 LRR_8 13 ltslddgaFkglsnLkvLdLsnNllttlspgafs 46 lts++ g+ +g + dLs+N ++ + + f+ FUN_000986-T1 251 LTSIPSGTLRG---FVSVDLSENYIENITASDFR 281 55555555554...45668999999999877775 PP == domain 2 score: 36.5 bits; conditional E-value: 3.1e-12 LRR_8 5 sLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 s+dLs N+++++ + F++ nL L+LsnN++++ls+g+f+ + ++ LdL++N + FUN_000986-T1 264 SVDLSENYIENITASDFRSFWNLYDLYLSNNKIKRLSNGTFREAKDITLLDLTSNEI 320 789****************************************************87 PP == domain 3 score: 38.6 bits; conditional E-value: 6.8e-13 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLp 49 nL+ L+Ls+N+++ l+ g+F+ + + LdL++N++++l+ ++f+gL+ FUN_000986-T1 285 NLYDLYLSNNKIKRLSNGTFREAKDITLLDLTSNEISHLEGDSFAGLE 332 799*******************************************97 PP == domain 4 score: 36.8 bits; conditional E-value: 2.6e-12 LRR_8 4 rsLdLssNrltslddgaFkglsn.LkvLdLsnNllttlspgafsgLpsLrsLd 55 + LdL+sN +++l+ ++F gl++ L+ LdLs+N+l+ l +++f++L+ L++L FUN_000986-T1 311 TLLDLTSNEISHLEGDSFAGLEGtLTLLDLSENKLKNLARESFHNLRVLTYLK 363 679*****************9865999************************97 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.7 0.0 3.8e-17 5.1e-14 7 79 .] 151 226 .. 145 226 .. 0.87 Alignments for each domain: == domain 1 score: 52.7 bits; conditional E-value: 3.8e-17 Ig_2 7 sptv.vtegesvtLtCsasgnppakytwykdgkvlsssqn...fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 ++++ + +g++ L+Csasg p+++++w++ g +l ++++ ++++nv+ d+G+Y+Cta+n ++g++s+++++tv FUN_000986-T1 151 TASHfLVKGQKTELRCSASGLPTPNVKWRRLGVELIEGRRfavLSLNNVTKADQGIYRCTASN-SQGQKSATMNLTV 226 4544489*********************************76444599***************.5699999***998 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.8 0.0 1.4e-16 1.9e-13 14 90 .] 158 226 .. 146 226 .. 0.93 Alignments for each domain: == domain 1 score: 50.8 bits; conditional E-value: 1.4e-16 I-set 14 eGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +G++ el c++sG p+p+v+W + g el e++r+ v L ++nv+k+D+G+Y+c+a+ns g+++a+++LtV FUN_000986-T1 158 KGQKTELRCSASGLPTPNVKWRRLGVELIEGRRFAV--------LSLNNVTKADQGIYRCTASNSQGQKSATMNLTV 226 79****************************999976........6677***************************98 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.1 0.0 1.3e-15 1.7e-12 9 78 .] 152 213 .. 144 213 .. 0.85 Alignments for each domain: == domain 1 score: 48.1 bits; conditional E-value: 1.3e-15 Ig_3 9 sstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 s+ +++g++ +L+C+a+g p+p+++W++ g el++g++ ++L+++nvt+ d+G Y+C+AsN FUN_000986-T1 152 ASHFLVKGQKTELRCSASGLPTPNVKWRRLGVELIEGRRF--------AVLSLNNVTKADQGIYRCTASN 213 4444899*************************87775554........8********************9 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.4 0.0 7e-14 9.4e-11 3 81 .] 154 222 .. 152 222 .. 0.94 Alignments for each domain: == domain 1 score: 42.4 bits; conditional E-value: 7e-14 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatlst 81 + + +G++ +L+Csas g p p+v+W++ g ++ie+++ + l ++nvt+ d G Y+C+++n+ g++++++ FUN_000986-T1 154 HFLVKGQKTELRCSAS-GLPTPNVKWRRLGVELIEGRR---------FAVLSLNNVTKADQGIYRCTASNSQGQKSATM 222 66778***********.*******************88.........99*************************99875 PP >> LRRNT Leucine rich repeat N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 1.3 7.9e-09 1.1e-05 1 25 [. 228 256 .. 228 257 .. 0.97 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 7.9e-09 LRRNT 1 aCPvpChCs....atvVnCsdrgLtavPr 25 aCP +C+Cs +++V+C + +Lt++P+ FUN_000986-T1 228 ACPDNCVCSfllyDLTVDCLRANLTSIPS 256 7***************************8 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.084 1.1e+02 9 35 .. 157 180 .. 152 185 .. 0.88 2 ! 21.3 0.0 2.4e-07 0.00032 72 108 .. 191 226 .. 182 227 .. 0.92 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.084 V-set 9 aeGesvtLtCslssseseasqsvyWyr 35 + G++ +L+Cs s ++ v+W r FUN_000986-T1 157 VKGQKTELRCSASGL---PTPNVKWRR 180 68********99998...999999988 PP == domain 2 score: 21.3 bits; conditional E-value: 2.4e-07 V-set 72 dfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 + l ++n+t +D+G+Y C ++++++++++++LtV FUN_000986-T1 191 FAVLSLNNVTKADQGIYRCT-ASNSQGQKSATMNLTV 226 57899***************.9**************9 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.18 2.4e+02 4 22 .. 264 282 .. 262 283 .. 0.85 2 ? 6.3 0.2 0.017 22 1 16 [. 285 300 .. 285 306 .. 0.76 3 ? 5.2 0.1 0.039 52 3 23 .] 311 331 .. 309 331 .. 0.87 4 ! 7.8 0.5 0.0053 7.2 2 23 .] 335 356 .. 334 356 .. 0.90 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.18 LRR_1 4 eLdLsnNnlsgllpeslgn 22 ++dLs N ++ + +++++ FUN_000986-T1 264 SVDLSENYIENITASDFRS 282 68*******9999988876 PP == domain 2 score: 6.3 bits; conditional E-value: 0.017 LRR_1 1 nLeeLdLsnNnlsgll 16 nL L+LsnN++ l+ FUN_000986-T1 285 NLYDLYLSNNKIKRLS 300 7889********6554 PP == domain 3 score: 5.2 bits; conditional E-value: 0.039 LRR_1 3 eeLdLsnNnlsgllpeslgnl 23 + LdL +N +s+l +s+++l FUN_000986-T1 311 TLLDLTSNEISHLEGDSFAGL 331 77*********9999999876 PP == domain 4 score: 7.8 bits; conditional E-value: 0.0053 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L+ LdLs N+l l es+ nl FUN_000986-T1 335 LTLLDLSENKLKNLARESFHNL 356 999********99999999887 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.2 2.6e-06 0.0035 13 69 .. 174 234 .. 159 235 .. 0.75 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 2.6e-06 Ig_4 13 keitwlkdgkeikeskek.tldlgksiedprglYqCk..eeekkkssslqvyyRmC.qNCv 69 +++w + g e e ++ l+l+++++ ++g+Y+C+ +++ +ks ++ + + C +NCv FUN_000986-T1 174 PNVKWRRLGVELIEGRRFaVLSLNNVTKADQGIYRCTasNSQGQKSATMNLTVEACpDNCV 234 567777755554444443489****************98778999***********77998 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.5 3.5e-06 0.0047 40 127 .. 258 347 .. 249 375 .. 0.82 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 3.5e-06 LRR_9 40 tldqfdtidlsdneirkld..gfPllkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslk.kltslsllrnpvtn 127 tl f ++dls+n i ++ +f + l l+l nn+i r+++g + + ++ l lt+n++++l d +a l+ lt l l +n + n FUN_000986-T1 258 TLRGFVSVDLSENYIENITasDFRSFWNLYDLYLSNNKIKRLSNGTFREAKDITLLDLTSNEISHLEG-DSFAGLEgTLTLLDLSENKLKN 347 7788999********9985226888999*************************************988.8999997357777777776544 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.0 9e-05 0.12 3 32 .. 147 178 .. 145 180 .. 0.76 2 ? 2.6 0.1 0.13 1.7e+02 83 112 .. 201 229 .. 185 239 .. 0.74 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 9e-05 Ig_PDGFR_d4 3 ilelsdsh..assgeqtvtCvaeGmPqPeveW 32 i++++ sh + ++ ++C a G+P+P+v+W FUN_000986-T1 147 IVDMTASHflVKGQKTELRCSASGLPTPNVKW 178 666776662235566789************** PP == domain 2 score: 2.6 bits; conditional E-value: 0.13 Ig_PDGFR_d4 83 kveetlavrCeaknelgadsrevkLvsstl 112 k ++ rC+a+n+ g++s ++L ++ FUN_000986-T1 201 KADQG-IYRCTASNSQGQKSATMNLTVEAC 229 44443.46***********99999977665 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 6.7e-06 0.009 5 78 .. 157 234 .. 154 236 .. 0.82 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 6.7e-06 Ig_5 5 isgttVtltCpeese..eeikWekndkelkd.keekeLvlenFsevedsGyysCykesskk.akhyLylkarvC.enCm 78 + g++ +l+C+ + ++kW++ + el + ++ L+l+n d+G y C++++s+ +++++ l + C +nC+ FUN_000986-T1 157 VKGQKTELRCSASGLptPNVKWRRLGVELIEgRRFAVLSLNNVTK-ADQGIYRCTASNSQGqKSATMNLTVEACpDNCV 234 568999999*976434499*****998865538889999999888.678*********98878999****999966886 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.16 2.2e+02 12 40 .. 250 276 .. 246 282 .. 0.79 2 ! 15.3 1.2 1.9e-05 0.025 6 40 .. 265 300 .. 263 301 .. 0.87 3 ! 14.7 1.7 2.9e-05 0.039 6 43 .. 289 324 .. 284 325 .. 0.89 4 ! 6.8 5.0 0.0093 12 3 30 .. 335 362 .. 334 373 .. 0.79 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.16 LRR_4 12 ritdidplskLpnLetLdLsgNnkitdls 40 ++t+i++ L ++dLs N i++++ FUN_000986-T1 250 NLTSIPSGT-LRGFVSVDLSEN-YIENIT 276 488888866.9999999**888.999996 PP == domain 2 score: 15.3 bits; conditional E-value: 1.9e-05 LRR_4 6 LdLsnNritdidp..lskLpnLetLdLsgNnkitdls 40 dLs N i++i ++++ nL L+L +Nnki+ ls FUN_000986-T1 265 VDLSENYIENITAsdFRSFWNLYDLYL-SNNKIKRLS 300 699*9********77779*********.777**9887 PP == domain 3 score: 14.7 bits; conditional E-value: 2.9e-05 LRR_4 6 LdLsnNritdidp..lskLpnLetLdLsgNnkitdlsdLk 43 L+LsnN+i+++++ ++ ++ + LdL++N ++s+L+ FUN_000986-T1 289 LYLSNNKIKRLSNgtFREAKDITLLDLTSN----EISHLE 324 9************98777*********999....888875 PP == domain 4 score: 6.8 bits; conditional E-value: 0.0093 LRR_4 3 LetLdLsnNritdidplskLpnLetLd.L 30 L+ LdLs N+++++ s ++nL++L L FUN_000986-T1 335 LTLLDLSENKLKNLARES-FHNLRVLTyL 362 899**********77777.******9755 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.0077 10 22 41 .. 159 178 .. 148 184 .. 0.86 2 ? 6.1 0.0 0.013 18 90 127 .. 190 227 .. 180 230 .. 0.73 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0077 Ig_VEGFR-1-like_5th 22 dqrhkltctafgipmpnitw 41 q+ +l c+a g+p pn+ w FUN_000986-T1 159 GQKTELRCSASGLPTPNVKW 178 68999**************9 PP == domain 2 score: 6.1 bits; conditional E-value: 0.013 Ig_VEGFR-1-like_5th 90 nrtistlvvktanvsgvysctarnelgnrtmripfyvd 127 ++ +l t g+y cta n g+++ + + v+ FUN_000986-T1 190 RFAVLSLNNVTKADQGIYRCTASNSQGQKSATMNLTVE 227 445555666677779************99887777665 PP >> CDCP1_CUB_6 CDCP1 CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 8.8e-05 0.12 17 46 .. 36 65 .. 28 85 .. 0.86 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 8.8e-05 CDCP1_CUB_6 17 lLatPnwpeGmkpsstvsWivsvpskqkae 46 +++Pn+p+ ++ +t +Wi+++p + a+ FUN_000986-T1 36 SFQSPNYPNHYPNGATCQWIIEIPYDIIAQ 65 579*********************988776 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.0003 0.41 13 42 .. 158 192 .. 145 225 .. 0.75 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0003 C2-set_2 13 eekevvatCvsaggkPapritWlldgkel......e 42 ++++ ++C sa+g P+p++ W + g el FUN_000986-T1 158 KGQKTELRC-SASGLPTPNVKWRRLGVELiegrrfA 192 3669999**.99************999985555443 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00035 0.47 49 86 .. 192 229 .. 178 231 .. 0.79 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00035 Izumo-Ig 49 stLtkpmvgledaGtYRCeLdtvksspatiihfkvtvl 86 ++L ++ v+ d+G YRC+ + + + ++ +v+ FUN_000986-T1 192 AVLSLNNVTKADQGIYRCTASNSQGQKSATMNLTVEAC 229 67999*************99887777666677666655 PP >> CUB_2 CUB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 1.4 0.00062 0.83 6 57 .. 25 65 .. 22 139 .. 0.81 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00062 CUB_2 6 CksgtvtinkpangsipvyYPetwnesaelpkipanqnCsyninvPkgyyak 57 Ck+ tv + +++ +s YP+ +p++ +C+++i++P + a+ FUN_000986-T1 25 CKNPTVLKREGSFQSPN--YPNH---------YPNGATCQWIIEIPYDIIAQ 65 76666666666555555..6666.........9*************877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (436 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 529 (0.0207086); expected 510.9 (0.02) Passed bias filter: 457 (0.01789); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 19 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4316.91 // Query: FUN_000987-T1 [L=1007] Description: FUN_000987 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-16 59.6 12.6 1e-05 25.7 2.4 4.7 5 LRR_8 Leucine rich repeat 1.3e-05 25.8 8.3 0.012 16.3 0.4 3.5 3 LRR_4 Leucine Rich repeats (2 copies) 0.0024 17.2 0.0 0.0057 16.0 0.0 1.5 1 TRP Transient receptor potential (TRP) ion chan 0.0026 18.0 25.0 0.23 11.8 4.6 4.7 4 Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B rec 0.0036 17.9 11.2 0.0036 17.9 11.2 2.6 2 DUF7630 Domain of unknown function (DUF7630) ------ inclusion threshold ------ 0.024 14.7 1.0 0.16 12.0 0.1 2.1 2 LRR_9 Leucine-rich repeat 0.094 13.1 25.7 0.88 10.0 0.3 5.8 5 TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like 0.83 10.4 3.3 8.3 7.2 0.1 2.8 3 DUF4381 Domain of unknown function (DUF4381) 1 10.0 11.9 1.1 9.9 0.4 3.2 2 CcmD Heme exporter protein D (CcmD) 2.2 9.3 8.3 13 7.0 0.1 5.1 5 LRR_1 Leucine Rich Repeat 6 8.1 5.3 1.3e+02 3.8 0.0 4.0 4 EphA2_TM Ephrin type-A receptor 2 transmembrane doma Domain annotation for each model (and alignments): >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.1 1.7e-08 4e-05 7 44 .. 73 110 .. 68 114 .. 0.91 2 ! 13.9 0.1 2.1e-05 0.049 16 49 .. 106 139 .. 103 141 .. 0.90 3 ! 25.7 2.4 4.5e-09 1e-05 3 46 .. 142 185 .. 140 200 .. 0.86 4 ? 3.1 0.0 0.05 1.2e+02 2 25 .. 190 213 .. 189 217 .. 0.86 5 ? -2.9 0.0 3.6 8.4e+03 16 35 .. 556 575 .. 548 580 .. 0.75 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 1.7e-08 LRR_8 7 dLssNrltslddgaFkglsnLkvLdLsnNllttlspga 44 dLs N+++++ F ls+L++L+LsnN+++ ls+g+ FUN_000987-T1 73 DLSENYIENVTAADFGYLSKLERLYLSNNKIKYLSNGT 110 7999****************************999886 PP == domain 2 score: 13.9 bits; conditional E-value: 2.1e-05 LRR_8 16 lddgaFkglsnLkvLdLsnNllttlspgafsgLp 49 l+ g+ ++ snL +++L +N++++++ ++f gL+ FUN_000987-T1 106 LSNGTVRKASNLLEFSLARNEISHMESDSFIGLE 139 677888999***********************96 PP == domain 3 score: 25.7 bits; conditional E-value: 4.5e-09 LRR_8 3 LrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafs 46 L +L L+ N ++ +d +F+gls+L +L +N l+ l+++af FUN_000987-T1 142 LAILFLNGNLIKFVDSYTFSGLSSLVLVNLADNPLQELNDHAFY 185 899****************************************6 PP == domain 4 score: 3.1 bits; conditional E-value: 0.05 LRR_8 2 nLrsLdLssNrltslddgaFkgls 25 +L++++L ++r + ++ +aF+g + FUN_000987-T1 190 SLHTIYLMNTRMERINIKAFEGQQ 213 7999****************9855 PP == domain 5 score: -2.9 bits; conditional E-value: 3.6 LRR_8 16 lddgaFkglsnLkvLdLsnN 35 l +++ ++ + ++L L++N FUN_000987-T1 556 LFPSWKQNAISKMYLMLGSN 575 66777788888899999999 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.4 5.1e-06 0.012 2 38 .. 92 126 .. 73 132 .. 0.76 2 ! 11.5 1.0 0.00017 0.39 4 41 .. 143 181 .. 141 183 .. 0.83 3 ? -0.6 0.0 1.1 2.6e+03 2 16 .. 190 204 .. 186 210 .. 0.63 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 5.1e-06 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitd 38 +Le+L+LsnN+i+ +++ +k nL + +L++N + FUN_000987-T1 92 KLERLYLSNNKIKYLSNgtVRKASNLLEFSLARN----E 126 6888888888888888865557888888888777....4 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00017 LRR_4 4 etLdLsnNritdidp..lskLpnLetLdLsgNnkitdlsd 41 L L++N i+ +d+ +s+L +L ++L++N ++++l+d FUN_000987-T1 143 AILFLNGNLIKFVDSytFSGLSSLVLVNLADN-PLQELND 181 579************77778*********777.7777765 PP == domain 3 score: -0.6 bits; conditional E-value: 1.1 LRR_4 2 nLetLdLsnNritdi 16 +L+t++L n+r+++i FUN_000987-T1 190 SLHTIYLMNTRMERI 204 455666666655554 PP >> TRP Transient receptor potential (TRP) ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 2.5e-06 0.0057 268 409 .. 755 897 .. 742 908 .. 0.89 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 2.5e-06 TRP 268 lLysdkkvlnkyGflyvqyrasrywffvpllvylfvkalfialaqgsgkvQvialliiEllylvllivlrPyedkrtnvlnilisvvnvlnailll 363 L s+++ l +fly++y+++++++ ++ + +v + i l ++ + v + i+ l+ v++++ +P d l+ + +v +ln+ + + FUN_000987-T1 755 QLNSESELLSGMSFLYENYNEDAWYWELVEVTRKLVLTCGIILIGRESRAYVGLASICSGLFAVAFAFRKPIRDDFEDKLQLTSLLVIFLNLGIGV 850 567788889999**********************************************************************99999999998766 PP TRP 364 vF.seefglpeivktvvGvvlfvvnaaltlvlliliivnaiiallsk 409 ++ +++ ++p v +++ l+ + + + vl+il++v+ ++a+l + FUN_000987-T1 851 ILkIPKESVPSDVDQYLDTLLVNILVVGANVLVILLVVGRYLAVLIH 897 653789999*********99999999999999999999998888754 PP >> Ephrin_rec_like Tyrosine-protein kinase ephrin type A/B receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.5 0.00046 1.1 8 36 .. 249 285 .. 244 291 .. 0.82 2 ! 11.8 4.6 0.0001 0.23 10 38 .. 296 329 .. 284 339 .. 0.85 3 ? 2.4 1.2 0.085 2e+02 19 43 .. 343 367 .. 335 371 .. 0.73 4 ! 6.3 0.7 0.005 12 11 35 .. 440 461 .. 436 465 .. 0.68 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00046 Ephrin_rec_like 8 letCipCprgtYqp........eegqlsClaCPlgtt 36 + + +pCp gt+ p ++ ++C++CP+g++ FUN_000987-T1 249 QTQRVPCPTGTFVPplknfqflTALESKCIPCPPGGF 285 555579******999999999999999******8764 PP == domain 2 score: 11.8 bits; conditional E-value: 0.0001 Ephrin_rec_like 10 tCipCprgtYqp.....eegqlsClaCPlgtttk 38 C pC +gtY p + l C+ CP+gt+t+ FUN_000987-T1 296 NCFPCNNGTYVPperapGKSVLHCTVCPTGTRTD 329 6***********77765566789********998 PP == domain 3 score: 2.4 bits; conditional E-value: 0.085 Ephrin_rec_like 19 YqpeegqlsClaCPlgtttkstgat 43 + + +++ C++CP+++ +++ FUN_000987-T1 343 FHRTMRFGPCEKCPATGLNCVDESV 367 556667888*****98766665555 PP == domain 4 score: 6.3 bits; conditional E-value: 0.005 Ephrin_rec_like 11 CipCprgtYqpeegqlsClaCPlgt 35 C+ C+ +Y+ ++l+C+ CP+gt FUN_000987-T1 440 CEVCEGSYYK---RALACKLCPSGT 461 6666666665...356777777765 PP >> DUF7630 Domain of unknown function (DUF7630) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 2.8 8.4 1.9e+04 27 45 .] 338 355 .. 319 355 .. 0.74 2 ! 17.9 11.2 1.6e-06 0.0036 3 42 .. 416 457 .. 415 459 .. 0.91 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 8.4 DUF7630 27 eCkkGYtnnfskgslCtkC 45 +C + + +++ + C+kC FUN_000987-T1 338 KCIDAFHRTMR-FGPCEKC 355 57777777776.5888888 PP == domain 2 score: 17.9 bits; conditional E-value: 1.6e-06 DUF7630 3 kCPiegaClg..kgkCaegmtgyLCaeCkkGYtnnfskgslC 42 +CP+ ++C g ++kCa+g+tg LC C+ Y++ + +lC FUN_000987-T1 416 QCPRAKSCEGglESKCAKGYTGPLCEVCEGSYYKRALACKLC 457 8*********999********************998876666 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 7.1e-05 0.16 48 113 .. 73 139 .. 64 159 .. 0.83 2 ? 0.8 0.1 0.18 4.3e+02 47 78 .. 169 203 .. 143 214 .. 0.49 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 7.1e-05 LRR_9 48 dlsdneirkl..dgfPllkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslk 113 dls+n i ++ +f +l +l+ l+l nn+i +++g + + nl e+ l++n+++++ d ++ l+ FUN_000987-T1 73 DLSENYIENVtaADFGYLSKLERLYLSNNKIKYLSNGTVRKASNLLEFSLARNEISHMES-DSFIGLE 139 99999998872257****************************************998765.6666665 PP == domain 2 score: 0.8 bits; conditional E-value: 0.18 LRR_9 47 idlsdneirkldgfPll...krlktlllnnnrilr 78 ++l+dn +++l++ + l+t++l n r+ r FUN_000987-T1 169 VNLADNPLQELNDHAFYianSSLHTIYLMNTRMER 203 34455555555444332111234555555555555 PP >> TNFR_ELAPOR1_6th ELAPOR1-like, TNF receptor-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.08 1.9e+02 5 22 .. 243 260 .. 242 264 .. 0.85 2 ? 5.2 4.1 0.012 28 11 26 .. 274 290 .. 269 304 .. 0.68 3 ? 2.3 4.7 0.095 2.2e+02 13 39 .. 296 329 .. 293 331 .. 0.67 4 ? 1.2 0.4 0.21 4.9e+02 28 34 .. 351 357 .. 348 359 .. 0.84 5 ? 10.0 0.3 0.00038 0.88 13 36 .. 439 461 .. 433 464 .. 0.91 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.08 TNFR_ELAPOR1_6th 5 GmeknnsstCefCpkgsy 22 G+++ n+++ +Cp+g++ FUN_000987-T1 243 GFANGNQTQRVPCPTGTF 260 888889999999999988 PP == domain 2 score: 5.2 bits; conditional E-value: 0.012 TNFR_ELAPOR1_6th 11 sstCefCpkg.sySdGt 26 +s+C +Cp+g +ySdG FUN_000987-T1 274 ESKCIPCPPGgFYSDGV 290 699****985389**95 PP == domain 3 score: 2.3 bits; conditional E-value: 0.095 TNFR_ELAPOR1_6th 13 tCefCpkgsySdGte.......eCkkCPagTePn 39 +C +C++g+y ++ C+ CP gT+ + FUN_000987-T1 296 NCFPCNNGTYVPPERapgksvlHCTVCPTGTRTD 329 6888888888755432222233699999999876 PP == domain 4 score: 1.2 bits; conditional E-value: 0.21 TNFR_ELAPOR1_6th 28 eCkkCPa 34 +C+kCPa FUN_000987-T1 351 PCEKCPA 357 7*****8 PP == domain 5 score: 10.0 bits; conditional E-value: 0.00038 TNFR_ELAPOR1_6th 13 tCefCpkgsySdGteeCkkCPagT 36 Ce+C+ +y +Ck CP gT FUN_000987-T1 439 LCEVCEGSYYKRAL-ACKLCPSGT 461 5*****99999999.*******99 PP >> DUF4381 Domain of unknown function (DUF4381) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.2 0.086 2e+02 20 45 .. 460 490 .. 457 508 .. 0.56 2 ? -3.2 0.0 5.6 1.3e+04 15 39 .. 568 591 .. 563 611 .. 0.43 3 ? 7.2 0.1 0.0036 8.3 27 53 .. 684 710 .. 675 723 .. 0.77 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.086 DUF4381 20 Gwwlll.alll....llllvlalwllrrrrr 45 G w+++ + ll l+l+ +++w rrr+ FUN_000987-T1 460 GTWVIVqLSLLgvavLVLITILIWSGRRRKS 490 5566665555563334555555555555554 PP == domain 2 score: -3.2 bits; conditional E-value: 5.6 DUF4381 15 wPpapGwwlllalllllllvlalwl 39 +++ +G + + +l++l+ +++ l FUN_000987-T1 568 MYLMLGSNVSV-ILFALISFWIRKL 591 55555533333.3333333333322 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0036 DUF4381 27 lllllllvlalwllrrrrrkrrealre 53 ++l +l+++alw++rr++ +r++ lr FUN_000987-T1 684 VVLPGLVFWALWRRRRQQLSRKRKLRD 710 567889999999999888888887775 PP >> CcmD Heme exporter protein D (CcmD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.1 0.0023 5.4 12 31 .. 471 490 .. 470 499 .. 0.89 2 ? 9.9 0.4 0.00046 1.1 16 38 .. 684 706 .. 680 712 .. 0.81 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0023 CcmD 12 gvtllvLaglilwsllqrrr 31 gv++lvL+ +++ws ++r+ FUN_000987-T1 471 GVAVLVLITILIWSGRRRKS 490 89****************97 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00046 CcmD 16 lvLaglilwsllqrrrllrelrr 38 +vL gl++w l++rrr++ +r FUN_000987-T1 684 VVLPGLVFWALWRRRRQQLSRKR 706 6899************9755555 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 4 9.3e+03 6 22 .. 73 89 .. 73 90 .. 0.81 2 ? 7.0 0.1 0.0056 13 1 13 [. 92 104 .. 92 112 .. 0.82 3 ? 1.4 0.1 0.41 9.5e+02 1 22 [. 116 137 .. 116 138 .. 0.86 4 ? -0.5 0.1 1.8 4.2e+03 2 23 .] 142 163 .. 141 163 .. 0.79 5 ? 0.6 0.1 0.78 1.8e+03 1 18 [. 165 182 .. 165 185 .. 0.77 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 4 LRR_1 6 dLsnNnlsgllpeslgn 22 dLs N ++ ++g FUN_000987-T1 73 DLSENYIENVTAADFGY 89 89*****8888877776 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0056 LRR_1 1 nLeeLdLsnNnls 13 +Le+L+LsnN++ FUN_000987-T1 92 KLERLYLSNNKIK 104 69*********94 PP == domain 3 score: 1.4 bits; conditional E-value: 0.41 LRR_1 1 nLeeLdLsnNnlsgllpeslgn 22 nL e++L++N +s+ ++s+ + FUN_000987-T1 116 NLLEFSLARNEISHMESDSFIG 137 7899********9999888865 PP == domain 4 score: -0.5 bits; conditional E-value: 1.8 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L +L L++N + ++ ++++l FUN_000987-T1 142 LAILFLNGNLIKFVDSYTFSGL 163 66899*****987877777765 PP == domain 5 score: 0.6 bits; conditional E-value: 0.78 LRR_1 1 nLeeLdLsnNnlsgllpe 18 +L ++L++N+l +l + FUN_000987-T1 165 SLVLVNLADNPLQELNDH 182 58889*******876655 PP >> EphA2_TM Ephrin type-A receptor 2 transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 0.065 1.5e+02 4 27 .. 468 491 .. 463 503 .. 0.55 2 ? -1.0 0.0 1.8 4.2e+03 12 34 .. 578 608 .. 570 622 .. 0.47 3 ? 3.8 0.0 0.057 1.3e+02 5 39 .. 679 713 .. 674 726 .. 0.61 4 ? -2.3 0.4 4.5 1.1e+04 2 13 .. 883 894 .. 874 911 .. 0.45 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.065 EphA2_TM 4 avagglvllvvvvvvlivrrrrkk 27 +++g+ vl+++ ++++ rrr+++ FUN_000987-T1 468 SLLGVAVLVLITILIWSGRRRKST 491 455555555555555555554433 PP == domain 2 score: -1.0 bits; conditional E-value: 1.8 EphA2_TM 12 lvvvvvvlivrr........rrkkrskaeqd 34 +++ +++ ++ r +++++sk++ + FUN_000987-T1 578 VILFALISFWIRklfllrsiNKEQSSKRRIE 608 2222233222222333334655555555444 PP == domain 3 score: 3.8 bits; conditional E-value: 0.057 EphA2_TM 5 vagglvllvvvvvvlivrrrrkkrskaeqdyeeke 39 + v+l +v+ +++rrrr++ s++++ + k+ FUN_000987-T1 679 ASSYTVVLPGLVFWALWRRRRQQLSRKRKLRDGKQ 713 33444444457777999998777666665543333 PP == domain 4 score: -2.3 bits; conditional E-value: 4.5 EphA2_TM 2 vgavagglvllv 13 v+ +++g +l v FUN_000987-T1 883 VILLVVGRYLAV 894 222223333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1007 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1376 (0.0538657); expected 510.9 (0.02) Passed bias filter: 778 (0.0304561); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.46u 0.41s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 9433.29 // Query: FUN_000988-T1 [L=576] Description: FUN_000988 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-26 93.5 0.0 3.2e-26 92.8 0.0 1.3 1 Beta-prop_WDR5 WDR5 beta-propeller domain 5.7e-26 91.6 0.0 2.1e-25 89.8 0.0 1.9 1 Beta-prop_THOC3 THOC3 beta-propeller domain 1.3e-25 89.5 0.0 2.4e-25 88.7 0.0 1.4 1 DUF1899 Domain of unknown function (DUF189 9e-23 81.4 0.0 6.2e-19 68.9 0.0 2.3 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1.4e-22 79.6 0.7 6.1e-06 27.0 0.0 5.1 5 WD40 WD domain, G-beta repeat 2.5e-19 69.9 0.0 1.2e-17 64.4 0.0 2.5 1 WD40_Prp19 Prp19 WD40 domain 2.6e-15 57.0 0.0 3.5e-08 33.6 0.0 2.3 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 4.8e-13 49.2 0.8 3e-12 46.6 0.0 2.2 2 WD40_4 Type of WD40 repeat 4.9e-13 49.4 0.1 4.2e-05 23.4 0.0 3.7 4 WD40_WDHD1_1st WDHD1 first WD40 domain 2.3e-11 43.8 0.0 2.5e-09 37.1 0.0 2.3 2 WDR55 WDR55 3.2e-10 40.0 0.2 6.1e-09 35.8 0.2 2.1 1 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 9.1e-10 38.8 0.0 0.00014 21.9 0.0 2.7 3 Beta-prop_EML_2 Echinoderm microtubule-associated 1.1e-08 35.2 0.1 1.7e-07 31.3 0.1 2.1 2 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 2.3e-08 34.0 0.0 4.4e-07 29.8 0.0 2.5 2 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 8.6e-08 32.0 0.0 8e-05 22.3 0.0 2.2 2 WD40_Gbeta G protein beta WD-40 repeat protei 1.4e-07 31.4 0.0 8.2e-05 22.4 0.0 2.3 2 EIF3I EIF3I 1.8e-07 31.3 0.0 1.2e-06 28.6 0.0 2.2 2 Beta-prop_RIG_2nd RIG second beta-propeller 2.9e-07 30.6 0.0 0.0019 18.1 0.0 2.5 2 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 3e-07 30.5 0.1 0.006 16.4 0.0 2.5 2 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 7.1e-07 29.9 0.0 0.062 14.0 0.0 4.0 4 ANAPC4_WD40 Anaphase-promoting complex subunit 2.4e-06 27.3 0.1 8.1e-05 22.2 0.0 3.0 4 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 2.4e-06 27.4 0.0 8.2e-06 25.7 0.0 1.8 1 Beta-prop_Aladin Aladin seven-bladed propeller 7.6e-06 26.3 0.6 0.43 11.1 0.1 4.6 5 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 1.1e-05 25.6 0.0 0.00077 19.5 0.0 2.5 3 Beta-prop_EIPR1 EIPR1 beta-propeller 3.1e-05 24.1 0.0 0.00063 19.8 0.0 2.2 2 Beta-prop_EML Echinoderm microtubule-associated 4.9e-05 23.1 0.0 0.00017 21.3 0.0 1.8 2 WDR90_beta-prop_4th WDR90, 4th beta-propeller 0.00015 21.6 0.0 0.0032 17.2 0.0 2.2 2 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 0.0007 19.1 0.0 0.29 10.4 0.0 2.2 2 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 0.0078 15.5 0.0 0.056 12.6 0.0 2.1 2 Beta-prop_IFT140_1st IFT140 first beta-propeller ------ inclusion threshold ------ 0.016 15.2 0.0 0.11 12.4 0.0 2.2 1 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 0.034 13.5 1.2 6.5 6.1 0.2 2.2 2 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 0.087 12.4 0.1 0.34 10.5 0.1 1.8 1 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 0.09 12.0 0.1 0.61 9.3 0.1 2.1 3 Beta-prop_WDR41 WDR41 0.17 11.2 0.0 0.41 9.9 0.0 1.6 1 Beta-prop_SCAP SCAP Beta-propeller 0.23 12.2 0.4 0.44 11.2 0.4 1.4 1 TSC22 TSC-22/dip/bun family 0.82 9.5 3.3 1.5 8.7 3.3 1.5 1 FAM76 FAM76 protein Domain annotation for each model (and alignments): >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.8 0.0 4.5e-29 3.2e-26 2 207 .. 82 304 .. 81 319 .. 0.70 Alignments for each domain: == domain 1 score: 92.8 bits; conditional E-value: 4.5e-29 Beta-prop_WDR5 2 lkghkkavssvkfsp.dgkllasasaDktikiwdv.......eegklektleghkkGisdvawssdsk.llasaSDDktvriwdvetg.kllktl 86 ++gh ++v ++ +p + + +as+s+D++ik+w+v + ++ l+gh++ ++ + w + ++ ++asa+ D vriwd+ ++ ++l FUN_000988-T1 82 VTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVpedglsmDLDEYLVDLRGHTRKVNIIRWHPCAEgVIASAAYDSEVRIWDIVDDrEAATIL 176 56888888888888866788999999999999998533322211236777889999999999999865488999999999999977551577889 PP Beta-prop_WDR5 87 kgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHs.dpvsavdfnrdgtlivsssy....Dgliriwdtetgqclktlve.ddn 175 kgH +++f+++Fn++g+ll+S+ D+++r+ d r+gk++ +H ++ s v+f d +++ ss + + i +wd+++ + ++ d++ FUN_000988-T1 177 KGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPgNKGSHVAFLGDMNMLFSSGFsrmnERQIALWDIRNLKKALKMDGvDTS 271 99999999999999999999999999999999999999988888852577889999999999999872222456889998876655555331233 PP Beta-prop_WDR5 176 ppvsfvkFspngkyi.LastldstirLwdyeke 207 + + + + k + La + d +ir ++++++ FUN_000988-T1 272 SGILLPFYDHDTKIVfLAGKGDGNIRYYEVSDS 304 333333334444433255566666666666555 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 89.8 0.0 2.9e-28 2.1e-25 1 196 [. 85 297 .. 85 312 .. 0.79 Alignments for each domain: == domain 1 score: 89.8 bits; conditional E-value: 2.9e-28 Beta-prop_THOC3 1 hkkkvhsvawsa.dGkrLasgsaDktvrvwnleksklsk.....etelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstat.vkt 87 h + v ++w++ + + +as+s+D +++vw++ ++ ls + l+ght++V+ ++w+p + ++a+a D+ vr+Wd+ +++at +k+ FUN_000988-T1 85 HGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPEDGLSMdldeyLVDLRGHTRKVNIIRWHPCAEGVIASAAYDSEVRIWDIVDDREAATiLKG 178 6778999****857799**************99987766232223579*********************************9998777772567 PP Beta-prop_THOC3 88 kgeni.nlawspdGktiavgskddtvslidvrtgkvkke.ekfk.kevnevafspdgkllllt....tgdgtvevlsypsleevktlka.htsn 173 + + i +l+++ +G+ +a++ kd+ +++id r gk ++ + ++ + vaf d ++l+++ +++ ++ ++++ +l++ ++++ +ts+ FUN_000988-T1 179 HPDIIfSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHgVGHPgNKGSHVAFLGDMNMLFSSgfsrMNERQIALWDIRNLKKALKMDGvDTSS 272 7777647****************************876525555478899***********9866667999***********999887525666 PP Beta-prop_THOC3 174 clcvaf.dpkgr.ylAvGsaDalvs 196 + + f d + + ++ +G D ++ FUN_000988-T1 273 GILLPFyDHDTKiVFLAGKGDGNIR 297 6666653333332344455555555 PP >> DUF1899 Domain of unknown function (DUF1899) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 88.7 0.0 3.3e-28 2.4e-25 2 66 .] 9 74 .. 8 74 .. 0.94 Alignments for each domain: == domain 1 score: 88.7 bits; conditional E-value: 3.3e-28 DUF1899 2 fvraSKfRhvygkpakkeecydnikvtksawd.snliaaNpkFlAvnwessGGGafaVlplsktgk 66 + r+SKf+hv+g+p kke+cy+ i+ ++++++ +nl+a+NpkFlAv +essGGG+f+Vlpl++ g+ FUN_000988-T1 9 VPRSSKFKHVFGNPCKKEKCYEAIRLSTHSTEgGNLCAVNPKFLAVALESSGGGTFLVLPLDQFGR 74 579************************9966537*****************************998 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.9 0.0 8.7e-22 6.2e-19 26 157 .. 83 224 .. 77 246 .. 0.82 2 ! 10.2 0.0 0.00091 0.65 10 67 .. 250 310 .. 243 316 .. 0.77 Alignments for each domain: == domain 1 score: 68.9 bits; conditional E-value: 8.7e-22 Beta-prop_WDR3_1st 26 egeksevtalaasp.dgkklavGyadgsirlwdl.......esgelevtfngHksavtalafdk.dgsrLasGskDtdiivwDvvaeagl. 106 +g+ + v ++ +p +++++a+ ++dgsi++w++ + e v ++gH+++v+++++++ ++ +as++ D+++ +wD+v+++ FUN_000988-T1 83 TGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVpedglsmDLDEYLVDLRGHTRKVNIIRWHPcAEGVIASAAYDSEVRIWDIVDDREAa 173 6777788888888856789**************95444333334557****************93456899**************987761 PP Beta-prop_WDR3_1st 107 frLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrse 157 LkgH d + s++f ++++l+s++kD+ i++ d + ++ v++ vgh ++ FUN_000988-T1 174 TILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPGN 224 579*************************************99999999765 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00091 Beta-prop_WDR3_1st 10 kvlvWdlkkgekvatlegeksevtalaa..spdgk.klavGyadgsirlwdlesgelevtf 67 ++++Wd+++ +k+ +++g +++ l +d+k ++ +G dg+ir ++++++e +tf FUN_000988-T1 250 QIALWDIRNLKKALKMDGVDTSSGILLPfyDHDTKiVFLAGKGDGNIRYYEVSDSEPYFTF 310 799*************987655555443113444336799*************99988887 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.0 5.9e-08 4.2e-05 7 38 .. 82 114 .. 79 115 .. 0.91 2 ! 20.3 0.0 1.2e-06 0.00083 5 39 .] 130 165 .. 126 165 .. 0.88 3 ! 27.0 0.0 8.6e-09 6.1e-06 5 39 .] 174 208 .. 170 208 .. 0.92 4 ? 1.0 0.0 1.5 1.1e+03 15 39 .] 227 255 .. 212 255 .. 0.67 5 ? -0.2 0.0 3.7 2.6e+03 26 38 .. 287 299 .. 278 300 .. 0.66 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 5.9e-08 WD40 7 lkgHtsgVtslafspdgsl.lasgsdDgtvklW 38 +gH +V ++ ++p ++ +as+s+Dg++k+W FUN_000988-T1 82 VTGHGRPVLDIEWNPFNDQeIASSSEDGSIKVW 114 47**778************9************* PP == domain 2 score: 20.3 bits; conditional E-value: 1.2e-06 WD40 5 rtlkgHtsgVtslafspdgsl.lasgsdDgtvklWd 39 l+gHt V+ ++++p +as+++D+ v++Wd FUN_000988-T1 130 VDLRGHTRKVNIIRWHPCAEGvIASAAYDSEVRIWD 165 5699**999************445889********9 PP == domain 3 score: 27.0 bits; conditional E-value: 8.6e-09 WD40 5 rtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++lkgH + + sl+f+ +gsllas ++D+++++ d FUN_000988-T1 174 TILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVID 208 569***999***********************987 PP == domain 4 score: 1.0 bits; conditional E-value: 1.5 WD40 15 tslafspdgsllasgs....dDgtvklWd 39 + +af d ++l+s++ + + lWd FUN_000988-T1 227 SHVAFLGDMNMLFSSGfsrmNERQIALWD 255 689999999**998852233577777776 PP == domain 5 score: -0.2 bits; conditional E-value: 3.7 WD40 26 lasg.sdDgtvklW 38 +++g + Dg+++ + FUN_000988-T1 287 FLAGkG-DGNIRYY 299 458955.****976 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.4 0.0 1.6e-20 1.2e-17 44 239 .. 81 290 .. 78 317 .. 0.66 Alignments for each domain: == domain 1 score: 64.4 bits; conditional E-value: 1.6e-20 WD40_Prp19 44 tlkghtkkvtavafhp.sedvlvsasaDktvrvwkkeek.......etaatlkkhkaevtslsvhptgd.ylvsaskDgtwalhdletgktllkvk 130 +++gh + v ++ ++p +++ + s+s+D++++vw+ +e+ e l+ h+ +v+ + hp+ + +++sa+ D+ + ++d+ +++ +++ FUN_000988-T1 81 KVTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPEDglsmdldEYLVDLRGHTRKVNIIRWHPCAEgVIASAAYDSEVRIWDIVDDREAATIL 176 567888888888888845567888888888888888776454444344456888888888888888766245677778888888888887777776 PP WD40_Prp19 131 deeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsg.avtslaFSeNGYyLAsa..s..edgtvklWDLRklknfktle.ldee 220 + + + i s++f +G+ll+ +kd+++++ D + +k va+ gh g + + +aF + +L s+ s +++++ lWD+R+lk+ +++ +d++ FUN_000988-T1 177 KGH-PDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPGnKGSHVAFLGDMNMLFSSgfSrmNERQIALWDIRNLKKALKMDgVDTS 271 544.45677888888888888888888888888888888888888875356778887766666554232223457888888888776666634555 PP WD40_Prp19 221 skvnsvaFDksgqyLavag 239 s + +D+ ++ +ag FUN_000988-T1 272 SGILLPFYDHDTKIVFLAG 290 5666666666666655543 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.6 0.0 4.9e-11 3.5e-08 130 213 .. 81 170 .. 33 176 .. 0.83 2 ! 25.1 0.0 2e-08 1.4e-05 112 257 .. 158 306 .. 157 318 .. 0.74 Alignments for each domain: == domain 1 score: 33.6 bits; conditional E-value: 4.9e-11 WD40_CDC20-Fz 130 tlkahkqevcglkwsp.dgrllAsGgndntvkiwdlrsl.......spllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgk 213 ++++h + v ++w+p +++ +As+++d+++k+w++ + + l l+ h+ +v + W+p ++++a+ D ++r+w++ FUN_000988-T1 81 KVTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPEDglsmdldEYLVDLRGHTRKVNIIRWHPCAEGVIASAA--YDSEVRIWDIVDDR 170 6899************66799*************9753211222223578899*********************87..7********97655 PP == domain 2 score: 25.1 bits; conditional E-value: 2e-08 WD40_CDC20-Fz 112 dgkilhhDvrtkelevvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaa.vkAlaWcpwkkslLatG.GGtaDktir 205 d++++++D+ + e++++lk+h + + +l+++ +g+llAs ++d+++++ d r + + + h +a+ + l +G + ++ ++i FUN_000988-T1 158 DSEVRIWDIVDDR-EAATILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPGNkGSHVAFLGDMNMLFSSGfSRMNERQIA 252 5667788887776.4568999999999999999999999999999999999999888777666665541556888887666666663346789999 PP WD40_CDC20-Fz 206 lwntnt...gkllksvdtgsqvtsllwskeekelvsthgysknqivlwkypslkk 257 lw++++ +++ vdt+s + l + ++ ++v g+ + +i+ +++++ ++ FUN_000988-T1 253 LWDIRNlkkALKMDGVDTSSGIL-LPFYDHDTKIVFLAGKGDGNIRYYEVSDSEP 306 99996521144577899999987.5666778889999999999999888877665 PP >> WD40_4 Type of WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.2 1.1 7.6e+02 5 12 .. 6 13 .. 6 17 .. 0.85 2 ! 46.6 0.0 4.3e-15 3e-12 1 38 [. 350 387 .. 350 394 .. 0.93 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1.1 WD40_4 5 sftVPRks 12 sf VPR s FUN_000988-T1 6 SFKVPRSS 13 8*****99 PP == domain 2 score: 46.6 bits; conditional E-value: 4.3e-15 WD40_4 1 vepisftVPRkskedFqdDLyPdtagtepaltAeeWls 38 vepi +tVPR+++ q DLyP t++++p++ A eW++ FUN_000988-T1 350 VEPIAMTVPRRQSGVIQRDLYPLTPSNIPSMKAREWID 387 8**********99***********************95 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 1.4e-06 0.001 123 158 .. 81 117 .. 77 128 .. 0.87 2 ! 16.2 0.0 8.9e-06 0.0063 121 166 .. 129 175 .. 121 182 .. 0.83 3 ! 23.4 0.0 5.9e-08 4.2e-05 99 162 .. 150 214 .. 135 243 .. 0.84 4 ! 8.3 0.0 0.0022 1.6 90 169 .. 184 268 .. 179 276 .. 0.78 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 1.4e-06 WD40_WDHD1_1st 123 tleghkapvlsvaldpkg.eylaSsscDGtvkiWdie 158 +++gh pvl ++ +p + + +aSss DG++k+W + FUN_000988-T1 81 KVTGHGRPVLDIEWNPFNdQEIASSSEDGSIKVWHVP 117 679*************65489*************986 PP == domain 2 score: 16.2 bits; conditional E-value: 8.9e-06 WD40_WDHD1_1st 121 qktleghkapvlsvaldpkge.ylaSsscDGtvkiWdieskecvktl 166 + l+gh+ +v ++ +p +e ++aS++ D +v+iWdi +++++ t+ FUN_000988-T1 129 LVDLRGHTRKVNIIRWHPCAEgVIASAAYDSEVRIWDIVDDREAATI 175 5789*************97653899*************999887654 PP == domain 3 score: 23.4 bits; conditional E-value: 5.9e-08 WD40_WDHD1_1st 99 kllaagseDftikvvsv.edsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskec 162 ++a+++ D ++++ ++ +d + ++ l+gh + + s++++ +g +laS++ D ++++ d + ++ FUN_000988-T1 150 GVIASAAYDSEVRIWDIvDDREAATILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKL 214 58999***********94556678899*****************************988776665 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0022 WD40_WDHD1_1st 90 thialskdgkllaagseDftikvvsvedsskqktleghkap.vlsvaldpkgeylaSssc....DGtvkiWdieskecvktlkvl 169 +++++ +g+lla+ +D +i+v++ + ++ ++ gh + va+ +++l Ss+ + ++ +Wdi++ +++ +++ + FUN_000988-T1 184 FSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPGNkGSHVAFLGDMNMLFSSGFsrmnERQIALWDIRNLKKALKMDGV 268 578999*******************999998888888876515669999999999999752222567899999887776666655 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.041 29 276 293 .. 99 116 .. 81 127 .. 0.70 2 ! 37.1 0.0 3.6e-12 2.5e-09 9 169 .. 138 304 .. 132 314 .. 0.77 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.041 WDR55 276 gkllassshdqkvkFwni 293 + +asss d ++k w + FUN_000988-T1 99 DQEIASSSEDGSIKVWHV 116 445777777777777776 PP == domain 2 score: 37.1 bits; conditional E-value: 3.6e-12 WDR55 9 lvvdisfhPsed.iiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekah.espiysl 102 +v+ i hP ++ +ia + +d +v ++ +++ + l+ h + + +++F+ +G+ l s+ kDk+i+v+d gkl+ + ++ + FUN_000988-T1 138 KVNIIRWHPCAEgVIASAAYDSEVRIWDIVDDRE---AATILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPgNKGSHVA 230 6788999**876599*************997653...455679************************************99886554404555555 PP WDR55 103 lvidenlla.tG...dddGtvklWDlRkkkavmelkehedy..isdlvvdeekklL.latsgdGtltvfnirkk 169 + d n+l+ +G ++ ++ lWD+R+ k+ ++++ ++ i +d+++k++ la gdG + ++++ + FUN_000988-T1 231 FLGDMNMLFsSGfsrMNERQIALWDIRNLKKALKMDGVDTSsgILLPFYDHDTKIVfLAGKGDGNIRYYEVSDS 304 55566665524533368899*******99999988866433115555677777776156679***999998765 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.8 0.2 8.6e-12 6.1e-09 15 109 .. 88 176 .. 77 216 .. 0.78 Alignments for each domain: == domain 1 score: 35.8 bits; conditional E-value: 8.6e-12 Beta-prop_CAF1B_HIR1 15 pvlsvDiqkksekkeeeevlrlasgGaDshvliWkvkieeegkvklelladltrhqkavnvvrfspsge.lLasgdDesviiiWklkee 102 pvl ++ ++ ++ +as+ D +++W+v ++ + e+l dl+ h++ vn++r+ p e ++as+ +s + iW ++ FUN_000988-T1 88 PVLDIEWNPFND-------QEIASSSEDGSIKVWHVPEDGLSMDLDEYLVDLRGHTRKVNIIRWHPCAEgVIASAAYDSEVRIWDIVDD 169 555555554433.......5799**************99999889999****************99876599************99999 PP Beta-prop_CAF1B_HIR1 103 eeeinll 109 +e++++l FUN_000988-T1 170 REAATIL 176 8765554 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0022 1.5 39 133 .. 39 145 .. 23 149 .. 0.68 2 ! 21.9 0.0 1.9e-07 0.00014 75 159 .. 130 215 .. 121 222 .. 0.89 3 ! 21.0 0.0 3.6e-07 0.00025 11 155 .. 150 303 .. 142 315 .. 0.72 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0022 Beta-prop_EML_2 39 ekearsvafspdgkllavGlk.dGsvlvldaetleevv....evkdrkeaisdikfsp.dgklLavgshdnkiylYdvskk......ykkvgkl 120 ++ + +a++p+ +a+ ++ G++lvl +++ +v +v+ + +++ di+++p +++ +a +s+d++i++++v ++ + + l FUN_000988-T1 39 TEGGNLCAVNPKFLAVALESSgGGTFLVLPLDQFGRVPidapKVTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPEDglsmdlDEYLVDL 132 4555666777665555555543678888888888777544445677889999999999778899999999999999998742322222344557 PP Beta-prop_EML_2 121 kghssfithlDws 133 +gh+ + + w+ FUN_000988-T1 133 RGHTRKVNIIRWH 145 7777777777775 PP == domain 2 score: 21.9 bits; conditional E-value: 1.9e-07 Beta-prop_EML_2 75 vevkdrkeaisdikfspdg.klLavgshdnkiylYdvskkykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkqv 159 v ++ ++++++ i+++p+ ++a ++ d+ + ++d+ ++ + ++ lkgh + i +l + ++++l s+++d ++ ++d + gk v FUN_000988-T1 130 VDLRGHTRKVNIIRWHPCAeGVIASAAYDSEVRIWDIVDDREAATILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLV 215 5667788999*******761588999**************************************************9999999876 PP == domain 3 score: 21.0 bits; conditional E-value: 3.6e-07 Beta-prop_EML_2 11 pqfvTagdDktvrlWdlekkklvakvkle..kearsvafspdgkllavGlkdGsvlvldaetleevve.vkdrkeaisdikfspdgklLavg.. 99 ++++a +D+ vr+Wd+ + + a++ + + + s++f+ +g+lla ++kd ++ v+d + ++ v++ v + ++ s ++f d ++L + FUN_000988-T1 150 GVIASAAYDSEVRIWDIVDDREAATILKGhpDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHgVGHPGNKGSHVAFLGDMNMLFSSgf 243 4678999999999999987666665533301458999999999999999999999999999999876527778899999999999999987656 PP Beta-prop_EML_2 100 ..shdnkiylYdvskkykkvgklkg..hssfithlDwsedskylqsn.sgdyellfwdakt 155 ++ i l+d++ ++kk+ k++g ss i+ + +d k++ gd+++ ++++++ FUN_000988-T1 244 srMNERQIALWDIR-NLKKALKMDGvdTSSGILLPFYDHDTKIVFLAgKGDGNIRYYEVSD 303 66788889999984.5677766666224566776667777776654325666666666665 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.1 2.4e-10 1.7e-07 172 286 .. 83 207 .. 77 213 .. 0.87 2 ? 1.4 0.0 0.29 2.1e+02 233 290 .. 243 303 .. 224 306 .. 0.62 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 2.4e-10 Beta-prop_WDR3_2nd 172 YGhklPvlsldis.sDsklivtgsaDknikiw.......GldfGDchkslfahddsvmsvafvpktH.ylfsagkdkkvkyWD.adkfeki 252 Gh Pvl+++ + + i+++s D +ik+w +d + l +h+ v +++ p + + sa+ d +v+ WD d e FUN_000988-T1 83 TGHGRPVLDIEWNpFNDQEIASSSEDGSIKVWhvpedglSMDLDEYLVDLRGHTRKVNIIRWHPCAEgVIASAAYDSEVRIWDiVDDREAA 173 599999999998634667799***********666663336888889999*************98762667999*********66999*** PP Beta-prop_WDR3_2nd 253 qtleghagevwalavsskgkfvvsashDksiRlw 286 + l+gh + + +l+ +g++++s+ +Dk iR+ FUN_000988-T1 174 TILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVI 207 ********************************86 PP == domain 2 score: 1.4 bits; conditional E-value: 0.29 Beta-prop_WDR3_2nd 233 fsagkdkkvkyWDadkfekiqtleghagev.walavsskgkfvv..sashDksiRlwerte 290 fs +++++ WD + +k ++++g l ++++ +v ++ D iR +e ++ FUN_000988-T1 243 FSRMNERQIALWDIRNLKKALKMDGVDTSSgILLPFYDHDTKIVflAGKGDGNIRYYEVSD 303 4445789999999999999999999655441444555444433322455688888888665 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.0 6.3e-10 4.4e-07 9 174 .. 99 266 .. 97 281 .. 0.60 2 ? -0.9 0.0 1.5 1.1e+03 10 35 .. 285 310 .. 279 326 .. 0.75 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 6.3e-10 Beta-prop_TEP1_2nd 9 dkvlvsGaedgslqvWkleesssqc.....llllkahqkavlgla...lsqkllasasedltvrlWskelltqpekaeslsslsvlrghtg 91 d+ + s +edgs++vW++ e +++ l+ l +h + v + ++ ++asa+ d vr+W +++ +++++l+gh FUN_000988-T1 99 DQEIASSSEDGSIKVWHVPEDGLSMdldeyLVDLRGHTRKVNIIRwhpCAEGVIASAAYDSEVRIWDI--------VDDREAATILKGHPD 181 45566778888888888876654321111155677777777665422256778888888888888853........334456778888888 PP Beta-prop_TEP1_2nd 92 avtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkd.dllvscs....sdGsvglWdiekeqrlgkfl 174 + sf+ +G+lla++ +d+++ + d r + ++++ + + + a+ d ++l s+ ++ ++lWdi++ ++ k+ FUN_000988-T1 182 IIFSLSFNYNGSLLASTCKDKKIRVIDPRA--GKLVAHGVGHPGNK-GSHVAFLGDmNMLFSSGfsrmNERQIALWDIRNLKKALKMD 266 888888888888888888888887777666..33444444333332.23344443325666542223356677777777766666655 PP == domain 2 score: -0.9 bits; conditional E-value: 1.5 Beta-prop_TEP1_2nd 10 kvlvsGaedgslqvWkleesssqcll 35 v+++G +dg+++ +++++s+ ++ FUN_000988-T1 285 IVFLAGKGDGNIRYYEVSDSEPYFTF 310 57789999999999999888765544 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.0 1.1e-07 8e-05 153 259 .. 98 213 .. 92 221 .. 0.81 2 ! 7.5 0.0 0.0036 2.6 147 223 .. 227 311 .. 214 318 .. 0.73 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 1.1e-07 WD40_Gbeta 153 ddnqivtssgdttcalwdi.etg......qqttvfvghtgdvmslslapdtrlfv.sgacdasaklwdvreglcrqt.fighesdinaiaffpnge 239 +d++i +ss d + +w + e g + + + ght v + p ++ ++ s a d+ +++wd+ + t + gh i +++f ng+ FUN_000988-T1 98 NDQEIASSSEDGSIKVWHVpEDGlsmdldEYLVDLRGHTRKVNIIRWHPCAEGVIaSAAYDSEVRIWDIVDDREAATiLKGHPDIIFSLSFNYNGS 193 689999999999999998744442221114567899************998765527789********987766555167999999********** PP WD40_Gbeta 240 alatgsddatcrlfdlradq 259 la+ d r++d ra + FUN_000988-T1 194 LLASTCKDKKIRVIDPRAGK 213 ***************99965 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0036 WD40_Gbeta 147 sccrflddnqivtssg.....dttcalwdietgqqttvfvgh..tgdvmslslapdtr.lfvsgacdasaklwdvreglcrqtfi 223 s + fl d +++ ssg + alwdi ++ + g + ++ dt+ +f++g d ++ ++v ++ tf+ FUN_000988-T1 227 SHVAFLGDMNMLFSSGfsrmnERQIALWDIRNLKKALKMDGVdtSSGILLPFYDHDTKiVFLAGKGDGNIRYYEVSDSEPYFTFL 311 6678999*9**99999444444578******999998887751122233333455666369****************99888886 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0072 5.1 280 316 .. 81 118 .. 77 126 .. 0.81 2 ! 22.4 0.0 1.2e-07 8.2e-05 5 179 .. 131 305 .. 128 318 .. 0.73 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0072 EIF3I 280 rvkGHFGPintlavhP.dGksyasggEdGyvrvhefdk 316 +v GH P+ + ++P + + +as +EdG ++v + + FUN_000988-T1 81 KVTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPE 118 78999999999999995567899999999999988765 PP == domain 2 score: 22.4 bits; conditional E-value: 1.2e-07 EIF3I 5 llkGheRaltqikynr..eGDllfsvakdkkasvwysen.GerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletktavr 97 l+Gh+R ++ i++ eG ++ s+a d+++ +w + e ++Gh ++s+ + + +ll+++ d+++++ d + Gk +++ + + FUN_000988-T1 131 DLRGHTRKVNIIRWHPcaEG-VIASAAYDSEVRIWDIVDdREAATILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPGNK 225 599**********9852144.899***********766515666679***************************************9877776666 PP EIF3I 98 svefsesgkl.lllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldkti.itghedgeiskydlktge 179 + ++ g++ +l++ ++ +i + dir+ +++ + + ++s + + + k++ ++g+ dg+i y+++++e FUN_000988-T1 226 GSHVAFLGDMnMLFSSGFSRMNERQIALWDIRNLKKALK----MDGVDTSSGILLPFYDHDTKIVfLAGKGDGNIRYYEVSDSE 305 555555544413334444455677899999998765432....23333344555555555554432578888999888887665 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 0.0 1.8e-09 1.2e-06 166 253 .. 87 175 .. 77 208 .. 0.89 2 ? -0.7 0.0 1.5 1e+03 13 69 .. 248 304 .. 242 317 .. 0.46 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 1.8e-09 Beta-prop_RIG_2nd 166 ryitdiawsplesnklAvvandkvivilefkeeernletlkk.itasaekasitsvkwsnansnlllsfsidgkvkvWdleepekeelt 253 r + di w+p++++ +A +++d i + + e+ +++ ++ + + + +++ ++w + + ++ s +d++v++Wd+ ++++++++ FUN_000988-T1 87 RPVLDIEWNPFNDQEIASSSEDGSIKVWHVPEDGLSMDLDEYlVDLRGHTRKVNIIRWHPCAEGVIASAAYDSEVRIWDIVDDREAATI 175 6688***************************99999999765156778*******************************9998886644 PP == domain 2 score: -0.7 bits; conditional E-value: 1.5 Beta-prop_RIG_2nd 13 DrrvalldlsklsakklsieslkvkskvlsLaWspdken.LAfgTaeGrvGildvekm 69 +r++al+d+ +l+ k l+++ + +s +l + d + g ++G + + +v+ + FUN_000988-T1 248 ERQIALWDIRNLK-KALKMDGVDTSSGILLPFYDHDTKIvFLAGKGDGNIRYYEVSDS 304 5556666655554.33445544444444443333333333222444444444444444 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.00074 0.53 31 65 .. 82 116 .. 79 124 .. 0.89 2 ! 18.1 0.0 2.7e-06 0.0019 23 89 .. 124 190 .. 119 206 .. 0.82 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00074 Beta-prop_WDR75_1st 31 lkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 + gh v ++ np n+ ++ s+s dg++++w FUN_000988-T1 82 VTGHGRPVLDIEWNPFNDQEIASSSEDGSIKVWHV 116 6799999**************************86 PP == domain 2 score: 18.1 bits; conditional E-value: 2.7e-06 Beta-prop_WDR75_1st 23 steecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktfvvgykilslyvsakh 89 +e + +l+ght +v + +p + + s++ d+ vr+wd +d t++ g++ + + s + FUN_000988-T1 124 DLDEYLVDLRGHTRKVNIIRWHPCAEGVIASAAYDSEVRIWDIVDDREAATILKGHPDIIFSLSFNY 190 56788999*************************************9999998888775555555555 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.0015 1.1 235 272 .. 81 119 .. 77 132 .. 0.84 2 ! 16.4 0.0 8.5e-06 0.006 204 275 .. 142 215 .. 135 219 .. 0.85 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0015 Beta-prop_WDR36-Utp21_2nd 235 kfsghknritDltfsp.darWlitasmDstirtwdlpsg 272 k +gh + D+ ++p + + + ++s D +i++w +p+ FUN_000988-T1 81 KVTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPED 119 5689**********986778899*************975 PP == domain 2 score: 16.4 bits; conditional E-value: 8.5e-06 Beta-prop_WDR36-Utp21_2nd 204 lvlhr.essllavalddfsilvvDi.dtrrvvRkfsghknritDltfspdarWlitasmDstirtwdlpsgkli 275 ++ h +++a a d ++++ Di d r+++ ++gh i l+f+ ++ l ++ D ir+ d +gkl+ FUN_000988-T1 142 IRWHPcAEGVIASAAYDSEVRIWDIvDDREAATILKGHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLV 215 555551346899999999******6588999999*********************************9999998 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.23 1.7e+02 37 67 .. 85 116 .. 80 127 .. 0.85 2 ? 7.2 0.0 0.011 8.1 36 73 .. 134 172 .. 126 183 .. 0.82 3 ! 14.0 0.0 8.7e-05 0.062 41 75 .. 183 217 .. 176 224 .. 0.91 4 ? -1.3 0.0 5.4 3.9e+03 53 74 .. 287 308 .. 278 316 .. 0.77 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.23 ANAPC4_WD40 37 edsevtslaWkp.dGklLavaysdgevrlldv 67 +++ v +++W+p + + +a + +dg++++ +v FUN_000988-T1 85 HGRPVLDIEWNPfNDQEIASSSEDGSIKVWHV 116 6788999***9868999***********9987 PP == domain 2 score: 7.2 bits; conditional E-value: 0.011 ANAPC4_WD40 36 kedsevtslaWkpd.GklLavaysdgevrlldvesgklv 73 +++++v+ ++W+p+ + ++a a d+evr+ d+ + + + FUN_000988-T1 134 GHTRKVNIIRWHPCaEGVIASAAYDSEVRIWDIVDDREA 172 67899*******973679**************9876655 PP == domain 3 score: 14.0 bits; conditional E-value: 8.7e-05 ANAPC4_WD40 41 vtslaWkpdGklLavaysdgevrlldvesgklvhs 75 + sl+++ +G lLa ++d ++r++d gklv + FUN_000988-T1 183 IFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAH 217 679****************************9976 PP == domain 4 score: -1.3 bits; conditional E-value: 5.4 ANAPC4_WD40 53 Lavaysdgevrlldvesgklvh 74 + + dg++r ++v++ + FUN_000988-T1 287 FLAGKGDGNIRYYEVSDSEPYF 308 5678899****99999887665 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.76 5.4e+02 147 162 .. 101 116 .. 78 129 .. 0.50 2 ! 22.2 0.0 1.1e-07 8.1e-05 239 327 .. 151 238 .. 144 244 .. 0.81 3 ? -0.3 0.0 0.79 5.6e+02 246 286 .. 248 289 .. 234 310 .. 0.61 4 ? -2.7 0.0 4.2 3e+03 130 166 .. 530 566 .. 526 571 .. 0.65 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.76 WD40_MABP1-WDR62_2nd 147 llasasRDRlihvfdv 162 +as+s D i+v+ v FUN_000988-T1 101 EIASSSEDGSIKVWHV 116 2344444444444433 PP == domain 2 score: 22.2 bits; conditional E-value: 1.1e-07 WD40_MABP1-WDR62_2nd 239 lvavacqDrnirvynvssgkqkks.fkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGecvatvfGhs.eivtglkFtedcr 325 ++a a+ D ++r++++ + ++ + +kg + ++++ g+ +a++c dk++ ++d ++G++va+ +Gh + + F d+ FUN_000988-T1 151 VIASAAYDSEVRIWDIVDDREAATiLKGHP---DIIFSLSFNYNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPgNKGSHVAFLGDMN 236 688999**********99988766155544...6899*************************************613344566666655 PP WD40_MABP1-WDR62_2nd 326 hl 327 l FUN_000988-T1 237 ML 238 55 PP == domain 3 score: -0.3 bits; conditional E-value: 0.79 WD40_MABP1-WDR62_2nd 246 Drnirvynvssgkqkksfkgsqsedgtllkvq.lDpsglyva 286 +r+i ++++++ k+ ++ g ++ g ll D +++a FUN_000988-T1 248 ERQIALWDIRNLKKALKMDGVDTSSGILLPFYdHDTKIVFLA 289 567777777777777777777777777665431333333333 PP == domain 4 score: -2.7 bits; conditional E-value: 4.2 WD40_MABP1-WDR62_2nd 130 dsevlcleyskpetglkllasasRDRlihvfdvekdy 166 d e l l ys+++++ +l + + + +++++ek+ FUN_000988-T1 530 DIETLRLAYSDQRDEIYFLQTQIKAKDAKILQLEKEN 566 5667777777777777777776666666666666655 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 1.2e-08 8.2e-06 60 179 .. 87 206 .. 81 213 .. 0.75 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 1.2e-08 Beta-prop_Aladin 60 ksvaslaWrPlsaselavacesg.vlvWtvdptslatrpssssaqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdv.aketavpLrr 150 + v +++W P+ +e+a + e+g + vW+v l+ + + r + + v + W+p ++ ++++++ d+++ +Wd+ + ++a ++ + FUN_000988-T1 87 RPVLDIEWNPFNDQEIASSSEDGsIKVWHVPEDGLSMDLDEYLVDL--RGHTRKVNIIRWHPCAEGVIASAAYDSEVRIWDIvDDREAATILK 177 5688999***********99987477****9988888776666553..233468999************************624445555555 PP Beta-prop_Aladin 151 vggggvsllkwspdgskllaatpssvfrv 179 + l+++ +gs l ++ + + rv FUN_000988-T1 178 GHPDIIFSLSFNYNGSLLASTCKDKKIRV 206 55556666788888876666666666776 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.019 13 12 28 .. 99 115 .. 92 120 .. 0.88 2 ! 11.1 0.1 0.0006 0.43 11 34 .. 148 171 .. 135 206 .. 0.80 3 ? -0.5 0.0 2.6 1.8e+03 11 36 .. 191 216 .. 179 219 .. 0.80 4 ? 0.2 0.0 1.5 1.1e+03 19 34 .. 246 261 .. 233 300 .. 0.67 5 ? 1.8 0.0 0.48 3.4e+02 56 72 .. 533 549 .. 527 550 .. 0.87 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.019 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWd 28 d+ i s+seD ++K+W FUN_000988-T1 99 DQEIASSSEDGSIKVWH 115 7889************7 PP == domain 2 score: 11.1 bits; conditional E-value: 0.0006 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdretkkq 34 + +i sA++D++v++Wd + + FUN_000988-T1 148 AEGVIASAAYDSEVRIWDIVDDRE 171 5789**************877765 PP == domain 3 score: -0.5 bits; conditional E-value: 2.6 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdretkkqvG 36 +l+ s +D+++++ d + k+v+ FUN_000988-T1 191 NGSLLASTCKDKKIRVIDPRAGKLVA 216 568899999*******9999999886 PP == domain 4 score: 0.2 bits; conditional E-value: 1.5 Beta-prop_TEP1_C 19 seDrtvKlWdretkkq 34 ++r++ lWd ++ k+ FUN_000988-T1 246 MNERQIALWDIRNLKK 261 5789999**9766554 PP == domain 5 score: 1.8 bits; conditional E-value: 0.48 Beta-prop_TEP1_C 56 eleLvcgDklGkvYfLs 72 +l+L+ +D++ ++YfL+ FUN_000988-T1 533 TLRLAYSDQRDEIYFLQ 549 678999*********96 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 1.1e-06 0.00077 205 280 .] 87 164 .. 23 164 .. 0.88 2 ! 12.4 0.0 0.00016 0.11 203 277 .. 135 204 .. 129 207 .. 0.85 3 ? 2.1 0.0 0.21 1.5e+02 169 238 .. 190 259 .. 188 280 .. 0.71 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 1.1e-06 Beta-prop_EIPR1 205 gkvravdfdpakknklltagddgvvlihDiRydgs..stveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 v +++++p + ++++++ +dg ++++ + dg + e l l++h+ v+ +++ p +++i s++ ds +++w FUN_000988-T1 87 RPVLDIEWNPFNDQEIASSSEDGSIKVWHVPEDGLsmDLDEYLVDLRGHTRKVNIIRWHPCAEGVIASAAYDSEVRIW 164 45789**************************99985445677899*******************************99 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00016 Beta-prop_EIPR1 203 gfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstl 277 + kv+ + ++p+ ++ +++a d+ v i+Di e + lk+h ++ + +fN + L+ s+ d+++ FUN_000988-T1 135 HTRKVNIIRWHPCAEGVIASAAYDSEVRIWDIV----DDREAATILKGHPDIIFSLSFNYN-GSLLASTCKDKKI 204 467888999***********************9....67788999*************954.5677777777766 PP == domain 3 score: 2.1 bits; conditional E-value: 0.21 Beta-prop_EIPR1 169 hdsslvlvace.sglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltag....ddgvvlihDiRydg 238 ++ sl + +c+ +++ +iD Ra k + + h +k v f +n+l ++g ++ ++ ++DiR + FUN_000988-T1 190 YNGSLLASTCKdKKIRVIDPRAGKLVA---HGVGHPGNKGSHVAFLG-DMNMLFSSGfsrmNERQIALWDIR-NL 259 667788889988999999999988777...44555556667777764.456666665444478899999999.43 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 8.8e-07 0.00063 105 229 .. 82 211 .. 78 230 .. 0.81 2 ? 1.5 0.0 0.34 2.4e+02 86 131 .. 246 292 .. 227 309 .. 0.70 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 8.8e-07 Beta-prop_EML 105 tktskdkvlavefhpldknllvtcGk.khiaFWtlegkkl..ekkkgifeksekpkyvlclafse..ngdvitGdsnGnilvWskgtnkiskavkk 195 ++++ +vl++e++p +++ + + + i+ W++ +++l + ++ +++ + + + v + +++ +g + ++ + ++ +W+ +++ ++ k FUN_000988-T1 82 VTGHGRPVLDIEWNPFNDQEIASSSEdGSIKVWHVPEDGLsmDLDEYLVDLRGHTRKVNIIRWHPcaEGVIASAAYDSEVRIWDIVDDREAATILK 177 6788899**********999998765279******87775214456666666666666666665411677889***********99999999999* PP Beta-prop_EML 196 ahegsvfsllvlkdgtllsgggkdgkivawdanl 229 h +fsl + +g+ll + kd+ki +d + FUN_000988-T1 178 GHPDIIFSLSFNYNGSLLASTCKDKKIRVIDPRA 211 **************************99888665 PP == domain 2 score: 1.5 bits; conditional E-value: 0.34 Beta-prop_EML 86 snehvlsvWdwqkgeklaetk.tskdkvlavefhpldknllvtcGkk 131 ne+ + +Wd+++ +k ++ +++ + + + f +d++++ Gk FUN_000988-T1 246 MNERQIALWDIRNLKKALKMDgVDTSSGILLPFYDHDTKIVFLAGKG 292 57788899999888887777514566778888888888887777764 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 2.4e-07 0.00017 11 124 .. 99 215 .. 89 232 .. 0.79 2 ? -1.7 0.0 2.4 1.7e+03 62 80 .. 287 305 .. 280 308 .. 0.83 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 2.4e-07 WDR90_beta-prop_4th 11 eshlatcsedGsvrvw.......slasmelvvqfqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsis.rtemelklhphaval 92 ++++a+ sedGs++vw s++ e +v+++ + + + w p + + +++ d +r++ i e l+ h+ + FUN_000988-T1 99 DQEIASSSEDGSIKVWhvpedglSMDLDEYLVDLRGHTRKVNIIRWHPCAEG-----VIASAAYDSEVRIWDIVdDREAATILKGHPDII 183 67899***********4444444445567799999999**********8766.....4444555999****9862455666677777889 PP WDR90_beta-prop_4th 93 taiaysadGqtilsgdkdGlvavssprtGvtl 124 ++++ +G ++ s+ kd + v pr+G + FUN_000988-T1 184 FSLSFNYNGSLLASTCKDKKIRVIDPRAGKLV 215 9***************************9765 PP == domain 2 score: -1.7 bits; conditional E-value: 2.4 WDR90_beta-prop_4th 62 vvaGysdGtlrvfsisrte 80 aG +dG +r + +s +e FUN_000988-T1 287 FLAGKGDGNIRYYEVSDSE 305 469************9875 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 4.6e-06 0.0032 7 101 .. 100 203 .. 96 214 .. 0.81 2 ? 1.9 0.0 0.2 1.5e+02 16 69 .. 249 305 .. 244 325 .. 0.79 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 4.6e-06 Beta-prop_WDR90_POC16_2nd 7 rqlatvseDetiriWd.......ldtlqqlydfsaseeaPcavafhPskq.vfacGfssGvvrvfsveatsl.laehkqhrgkv 81 +++a seD +i++W+ +d + l d+ ++ + +hP + v+a+ + vr++++ + + k h + FUN_000988-T1 100 QEIASSSEDGSIKVWHvpedglsMDLDEYLVDLRGHTRKVNIIRWHPCAEgVIASAAYDSEVRIWDIVDDREaATILKGHPDII 183 7899***********8332232234557899****************865388999999*******9776550556788999** PP Beta-prop_WDR90_POC16_2nd 82 tglvfspdgeylysacslGs 101 +l f+ +g++l s+c+ + FUN_000988-T1 184 FSLSFNYNGSLLASTCKDKK 203 ****************8765 PP == domain 2 score: 1.9 bits; conditional E-value: 0.2 Beta-prop_WDR90_POC16_2nd 16 etiriWdldtlqqlydfsaseeaPcav.af..hPskqvfacGfssGvvrvfsveats 69 + i +Wd+ +l++ + + + + f h +k vf +G +G +r+++v++++ FUN_000988-T1 249 RQIALWDIRNLKKALKMDGVDTSSGILlPFydHDTKIVFLAGKGDGNIRYYEVSDSE 305 67889999999999988876654443324445889999***************9886 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.1 0.0055 3.9 241 316 .. 99 180 .. 97 188 .. 0.76 2 ! 10.4 0.0 0.00041 0.29 189 310 .. 187 309 .. 176 321 .. 0.73 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0055 Beta-prop_DCAF4 241 eqlllaadmaGkiklwdlra.......tkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllrtipspyp 316 +q + ++ G ik+w + + + + +Gh+ + ++ h eG+++++ d riw + d + ti +p FUN_000988-T1 99 DQEIASSSEDGSIKVWHVPEdglsmdlDEYLVDLRGHTRKVNIIRWHP-CAEGVIASAAYDSEVRIWDIVDDREAATILKGHP 180 56667777788999997754111111134566779********99996.579*******************999888877666 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00041 Beta-prop_DCAF4 189 qfalqapllfnGcrsGeifaidlrqrsr..kgkgwkatrlfhdsavtsvqllqeeqlllaadm.aGkiklwdlratkcvkqyeGhvneyay.lp 278 f + ll + c+ +i id r + +g g + + +h + + +++l + + m +i lwd+r+ k + +G + + lp FUN_000988-T1 187 SFNYNGSLLASTCKDKKIRVIDPRAGKLvaHGVGHPGNKGSHVAFLGDMNMLFSSGFS---RMnERQIALWDIRNLKKALKMDGVDTSSGIlLP 277 5777777888888888888888888775334555556666666666666666655543...331368*****************9888765279 PP Beta-prop_DCAF4 279 lhvneeeGllvavGqdcytriwslkdahllrt 310 ++ ++ + + +a d r + + d++ t FUN_000988-T1 278 FYDHDTKIVFLAGKGDGNIRYYEVSDSEPYFT 309 99999999999988899999999998876555 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.59 4.2e+02 101 134 .. 85 119 .. 50 125 .. 0.69 2 ! 12.6 0.0 8e-05 0.056 60 121 .. 136 199 .. 104 208 .. 0.84 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.59 Beta-prop_IFT140_1st 101 hkaeitvlewss.ngsrLvsgdksGvlvvWkldqr 134 h + +ew+ n ++++s+ + G++ vW++ + FUN_000988-T1 85 HGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPED 119 44555666776524566777777777777776555 PP == domain 2 score: 12.6 bits; conditional E-value: 8e-05 Beta-prop_IFT140_1st 60 svqvtvlsWHPtkk.ilavgwesGevlvlneqd.keltelpklhkaeitvlewssngsrLvsgd 121 + +v +++WHP + ++a + ++ev ++ d +e ++ k h i l+++ ngs L+s+ FUN_000988-T1 136 TRKVNIIRWHPCAEgVIASAAYDSEVRIWDIVDdREAATILKGHPDIIFSLSFNYNGSLLASTC 199 567899*****8653888889999*****9765277788999*****************99974 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00015 0.11 166 262 .. 103 206 .. 81 208 .. 0.80 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00015 Beta-prop_WDR36-Utp21_1st 166 aiglasGeivlhnikkdetllklkq.......eegpvtsisFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkl 242 a + ++G+i + ++ d ++l++ ++ +v+ i e v+a++ + ++ +wd+ + r + ++ + H + +l FUN_000988-T1 103 ASSSEDGSIKVWHVPEDGLSMDLDEylvdlrgHTRKVNIIRWHPCAEGVIASAAYDSEVRIWDIVDDREAATILKGHPDIIFSL 186 5556677777777666555555543333322278899999999999*********************9999999********** PP Beta-prop_WDR36-Utp21_1st 243 eflpgqpllvtsgaDNslke 262 +f + ll ++ +D ++++ FUN_000988-T1 187 SFNYNGSLLASTCKDKKIRV 206 **************988875 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.01 7.3 109 148 .. 83 124 .. 75 128 .. 0.85 2 ? 6.1 0.2 0.0091 6.5 105 149 .. 129 175 .. 125 185 .. 0.87 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.01 Beta-prop_DCAF12 109 kghkdwifaiaw..lsdtvavsGsrdgtlalwrvdpdklnas 148 gh + i w +d+ + s s dg++ +w+v +d l+++ FUN_000988-T1 83 TGHGRPVLDIEWnpFNDQEIASSSEDGSIKVWHVPEDGLSMD 124 57888888999966799999****************998876 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0091 Beta-prop_DCAF12 105 lGdrkghkdwifaiaw..lsdtvavsGsrdgtlalwrvdpdklnasi 149 l d +gh+ + i w ++ v+ s + d+ + +w + d+ a+i FUN_000988-T1 129 LVDLRGHTRKVNIIRWhpCAEGVIASAAYDSEVRIWDIVDDREAATI 175 67999***********555899****************999877665 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.1 0.00048 0.34 67 125 .. 82 146 .. 78 168 .. 0.72 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00048 Beta-prop_WDR35_TULP_N 67 legHsgavqvvaWNe.kykkLtssDenGliivWmlykg....swveeminnrnk.svvkdlkWss 125 + gH v ++WN + + ++ss e+G i vW + ++ e +++ r + +v+ ++W++ FUN_000988-T1 82 VTGHGRPVLDIEWNPfNDQEIASSSEDGSIKVWHVPEDglsmDLDEYLVDLRGHtRKVNIIRWHP 146 679***********846789*************99775222123344566554313455666655 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.0096 6.8 330 352 .. 96 118 .. 75 125 .. 0.76 2 ? 9.3 0.1 0.00086 0.61 53 121 .. 99 168 .. 94 182 .. 0.73 3 ? 2.1 0.0 0.13 93 334 368 .. 150 186 .. 127 241 .. 0.61 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0096 Beta-prop_WDR41 330 klpnrqlvscsedgsvriwelre 352 ++++++ s sedgs+++w + e FUN_000988-T1 96 PFNDQEIASSSEDGSIKVWHVPE 118 46788999***********9876 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00086 Beta-prop_WDR41 53 dfrfasagddgivflwdv.......qtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdies 121 d +as+++dg++ +w+v + e l++l+ght+k+ i + +i +a+ d v +wdi FUN_000988-T1 99 DQEIASSSEDGSIKVWHVpedglsmDLDEYLVDLRGHTRKVNIIRWHPC------AEGVIASAAYDSEVRIWDIVD 168 6778999*********984322222345899999999999988765554......345777788888888888755 PP == domain 3 score: 2.1 bits; conditional E-value: 0.13 Beta-prop_WDR41 334 rqlvscsedgsvriwelrekkkssa..esvptglfsm 368 + s + d vriw++ + +++ + + p +fs+ FUN_000988-T1 150 GVIASAAYDSEVRIWDIVDDREAATilKGHPDIIFSL 186 4456677777788887766654443113445555554 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00058 0.41 314 407 .. 147 245 .. 132 266 .. 0.77 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00058 Beta-prop_SCAP 314 aaaGrvvtGsqdhtvrvyrl.edscclftlqGhsGgitavyid.qtmvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvc...ttscviss 403 a G + + + d vr++ + +d l+Gh i ++ + + +las +d i + d +G v+h gh G+ s v ++ ss FUN_000988-T1 147 CAEGVIASAAYDSEVRIWDIvDDREAATILKGHPDIIFSLSFNyNGSLLASTCKDKKIRVIDPRAGKLVAHGVGHPGNKGSHVAflgDMNMLFSS 241 4678888889999*****872566677779********99876367899**************************99887766411145677788 PP Beta-prop_SCAP 404 Gldd 407 G+ FUN_000988-T1 242 GFSR 245 7654 PP >> TSC22 TSC-22/dip/bun family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.4 0.00063 0.44 13 43 .. 542 572 .. 539 575 .. 0.93 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00063 TSC22 13 rEeVevLkekIaeLeeriseleeENsiLral 43 r+e+ L+++I+ ++i +le+EN++Lr++ FUN_000988-T1 542 RDEIYFLQTQIKAKDAKILQLEKENQFLREK 572 899999***********************86 PP >> FAM76 FAM76 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 3.3 0.0021 1.5 147 255 .. 462 574 .. 411 576 .] 0.47 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0021 FAM76 147 sklkkkkkksekekkhklksekkshhskrss..........rvdvsklk.....sekn..........lp......kklarekesnedsaatvdan 211 +++++++ + ++v + + +p +r +++++ s + + FUN_000988-T1 462 NHMNSSRG----------------------QngeagihyvqATEV---RsfpenK--HrdpiqvtakaVPsnrsttGSEKRRSQGDRRSGDFSNWD 530 11111111......................122222222221111...1222220..122333333335521110022223333333333344444 PP FAM76 212 ssdhvvaitqLkekiasLkkqlsqkdqqlLekdkkiteLkaknf 255 +a ++ +++i L+ q++ kd+++L+ +k+ L+ k++ FUN_000988-T1 531 IETLRLAYSDQRDEIYFLQTQIKAKDAKILQLEKENQFLREKTQ 574 44556788999******************999998877777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (576 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 827 (0.0323742); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 36 [number of targets reported over threshold] # CPU time: 0.46u 0.37s 00:00:00.83 Elapsed: 00:00:00.44 # Mc/sec: 5258.73 // Query: FUN_000989-T1 [L=202] Description: FUN_000989 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-65 218.5 0.0 6.3e-65 218.3 0.0 1.0 1 CDO_I Cysteine dioxygenase type I 0.0093 15.9 0.0 0.015 15.3 0.0 1.4 1 PCO_ADO PCO_ADO Domain annotation for each model (and alignments): >> CDO_I Cysteine dioxygenase type I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 218.3 0.0 4.9e-69 6.3e-65 7 170 .] 9 174 .. 1 174 [. 0.96 Alignments for each domain: == domain 1 score: 218.3 bits; conditional E-value: 4.9e-69 CDO_I 7 lkastladlvaqlrelfrrkavdveevaslmeayksdatewaryaklDqekytrnlvdaGnGkfnlmilcWgpGtgssvhDhtdshcflkildGeL 102 +++tl d+v+ l+ f+++ vdveev s+ ++y+s++++w++ya +D+++ytrnlvd GnGkfn+++lcWg+G+gss+hDh+dshcflk+ldG L FUN_000989-T1 9 KSPETLEDVVKGLHVYFEEDHVDVEEVISFLSSYRSNPSDWSKYANYDPHRYTRNLVDEGNGKFNVIVLCWGEGQGSSIHDHADSHCFLKVLDGRL 104 5899******************************************************************************************** PP CDO_I 103 ketklawprk..kleeldkkeekvllengvayindelglhrvenlshdegavslhlYiPPldtirafdrr 170 ket++ wp + ++++ k + + +n+v yind++glhrven+sh++ a slh+YiP +d +r fd+r FUN_000989-T1 105 KETQFPWPSEsePEKPIEPKGSRFYETNEVNYINDSIGLHRVENVSHTDTAASLHVYIPAFDVCRSFDQR 174 ********99555678899999**********************************************97 PP >> PCO_ADO PCO_ADO # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 1.1e-06 0.015 43 92 .. 71 120 .. 50 173 .. 0.85 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 1.1e-06 PCO_ADO 43 sfslgiFllppgaviPLHdHpgMtvlskllyGslhiksydwveeaedsee 92 +f +++ + +g+ +HdH + ++k+l G+l+ + + w +e+e+++ FUN_000989-T1 71 KFNVIVLCWGEGQGSSIHDHADSHCFLKVLDGRLKETQFPWPSESEPEKP 120 7999999999999999*************************996666543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (202 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 702 (0.0274809); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.43s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2000.27 // Query: FUN_000990-T1 [L=129] Description: FUN_000990 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.6e-12 46.1 26.4 9.9e-10 39.3 26.4 2.1 1 RAM mRNA cap methylation, RNMT-activating mini protein Domain annotation for each model (and alignments): >> RAM mRNA cap methylation, RNMT-activating mini protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 26.4 3.9e-14 9.9e-10 2 78 .. 11 93 .. 10 123 .. 0.62 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 3.9e-14 RAM 2 ceeeFkdRFTedDeeYqkylkrpaekPpivepWnek........grgggnqrnrdnRfndrrggsdrgrdrrrgrggdrrsnsqy 78 +ee F++R+T++D eY+k ++r++++Pp++ +W + +rg g + +++R++ +r++++r d++ +r+gd r++ + FUN_000990-T1 11 FEEVFSKRYTSEDVEYMKTVNRQQPSPPCLTDWGNVgyrdgrhdNRGDG-RGFDRSRHDGGRDHGRRYGDHDDNRRGDDRYR-HR 93 8*********************************333334444322222.22223344433333333333333333333333.22 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 622 (0.0243492); expected 510.9 (0.02) Passed bias filter: 414 (0.0162067); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1309.59 // Query: FUN_000991-T1 [L=189] Description: FUN_000991 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (189 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 690 (0.0270112); expected 510.9 (0.02) Passed bias filter: 464 (0.018164); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1865.97 // Query: FUN_000992-T1 [L=353] Description: FUN_000992 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-136 455.7 0.4 1.4e-136 455.5 0.4 1.0 1 G-alpha G-protein alpha subunit 2.4e-14 53.7 0.8 1.5e-10 41.4 0.1 2.8 2 Arf ADP-ribosylation factor family 0.0054 16.7 0.2 0.3 10.9 0.0 2.3 2 Gtr1_RagA Gtr1/RagA G protein conserved region ------ inclusion threshold ------ 0.02 15.2 0.0 0.28 11.5 0.0 2.1 2 RsgA_GTPase RsgA GTPase 0.084 12.9 0.0 1.4 8.9 0.0 2.2 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 TniB Bacterial TniB protein 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 FtsK_SpoIIIE FtsK/SpoIIIE family 0.23 11.7 0.0 0.44 10.8 0.0 1.4 1 AAA_29 P-loop containing region of AAA domain 0.26 12.0 0.2 8.4 7.2 0.0 2.5 2 Roc Ras of Complex, Roc, domain of DAPkinase Domain annotation for each model (and alignments): >> G-alpha G-protein alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 455.5 0.4 5e-140 1.4e-136 2 333 .] 14 342 .. 13 342 .. 0.99 Alignments for each domain: == domain 1 score: 455.5 bits; conditional E-value: 5e-140 G-alpha 2 rkskeidkqlkeekkkakkevklLllGageSGKsTilkqmkilhkkgfseeerkeyraviysnilrslktllealekleieleeeenkerlkklls 97 r++ eid+qlk +k+++++e+klLllG+geSGKsT++kqm+i+h++g+s+e+++ y +++y+ni++++++l a+e+l+i+++++ n e+++++++ FUN_000992-T1 14 RINAEIDRQLKIDKRNQRRELKLLLLGTGESGKSTFIKQMRIIHGQGYSDEDKRGYVPLVYQNIITAMHSLTLAMESLNIPYKDPANPEHARYIRE 109 7899******************************************************************************************** PP G-alpha 98 lesslkeeeefsselaeaikelwndpgiqevyerrnefqledsaeyfldnldriaspdYvpteeDilrarvkttGitetkfelkklkfrlvdvgGq 193 ++++ + ++f++ ++ea k+lwnd+g++e+y+rr+e+ql+dsa+y+l +ldr+a+p+Y pte+D+lrar +t+Gi+e+ f+l+ + fr+vdvgGq FUN_000992-T1 110 VDPK--NVTTFEKSYYEATKSLWNDEGMKECYDRRREYQLSDSAKYYLTDLDRLAEPNYLPTEQDVLRARAPTSGIIEYPFDLETIIFRMVDVGGQ 203 ***9..9***************************************************************************************** PP G-alpha 194 rserkkWihcfedvtaiiFvvslseydqvlyedeetnrleeSlklFeeivnsklfkntsiiLflNKiDlfeeKlkksplskyfpeyegnpndveea 289 rser+kWihcfe+vt+i+F+v+lseydqvl+e+ ++nr+eeS++lF++i++ ++f+n+siiLflNK+Dl+eeK+ s+l +yfpe++g + d+++a FUN_000992-T1 204 RSERRKWIHCFENVTSIMFLVALSEYDQVLVESANENRMEESKALFRTIITYPWFQNSSIILFLNKKDLLEEKIMFSHLAEYFPEFDGPQCDAQAA 299 ************************************************************************************************ PP G-alpha 290 lkyikekfkelnkenkkkkiythftcatdtenvkkvfeavkdii 333 ++i ++f +ln +++k iy+hftcatdten+++vf+avkd+i FUN_000992-T1 300 REFILKMFVDLNP-DSDKIIYSHFTCATDTENIRFVFAAVKDTI 342 ***********98.9999************************97 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.1 0.00029 0.84 10 35 .. 29 54 .. 21 62 .. 0.85 2 ! 41.4 0.1 5.1e-14 1.5e-10 40 129 .. 175 274 .. 168 286 .. 0.84 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00029 Arf 10 lkkkelrilllGLDnaGKtTilkklk 35 ++++el++lllG ++GK+T +k+++ FUN_000992-T1 29 NQRRELKLLLLGTGESGKSTFIKQMR 54 3489*****************99875 PP == domain 2 score: 41.4 bits; conditional E-value: 5.1e-14 Arf 40 vttiPTigfnveeveiknlkftvwDvGGqeklRplWknYfektdavifvv..........DsadreRleeakeeLkalleeeelkeaallvlaNKq 125 PT g +++ f++ DvGGq++ R+ W + fe++++++f+v +sa+++R+ee+k+ ++++++ ++ ++++ NK+ FUN_000992-T1 175 RARAPTSGIIEYPFDLETIIFRMVDVGGQRSERRKWIHCFENVTSIMFLValseydqvlvESANENRMEESKALFRTIITYPWFQNSSIILFLNKK 270 5678999999999999*******************************975333332222279999******************************* PP Arf 126 Dlpe 129 Dl e FUN_000992-T1 271 DLLE 274 *965 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.02 56 1 17 [. 35 51 .. 35 66 .. 0.88 2 ! 10.9 0.0 0.00011 0.3 45 129 .. 190 278 .. 166 289 .. 0.79 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.02 Gtr1_RagA 1 kvLLmGksksGKsSirs 17 k+LL+G +sGKs + FUN_000992-T1 35 KLLLLGTGESGKSTFIK 51 89***********8754 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00011 Gtr1_RagA 45 lgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDve.......skeleedlarlketlealsev..speakvfvlihKvDlisedkr 129 l+ + + ++d+gGq++ + + f+nv ++++++ + ++ e+ +++ k ++++++++ ++ ++ +++K Dl++e+ FUN_000992-T1 190 LETIIFRMVDVGGQRSERRK-----WIHCFENVTSIMFLVALSeydqvlvESANENRMEESKALFRTIITYpwFQNSSIILFLNKKDLLEEKIM 278 5678999*******987666.....589***********99987777776223555666666666666655227999************99865 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.12 3.3e+02 109 127 .. 36 54 .. 9 69 .. 0.78 2 ? 11.5 0.0 9.8e-05 0.28 21 77 .. 227 284 .. 206 306 .. 0.75 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.12 RsgA_GTPase 109 tvllGqSGvGKStLinall 127 +llG GKSt+i++++ FUN_000992-T1 36 LLLLGTGESGKSTFIKQMR 54 5678888899*****9875 PP == domain 2 score: 11.5 bits; conditional E-value: 9.8e-05 RsgA_GTPase 21 aNvdqvvivvslkepefnlrlldrfLvla.eesgiepvivlnKiDlleeeeeleelkk 77 + dqv++ ++ ++ +++ l r ++++ + ++ ++++ lnK Dllee+ +++l++ FUN_000992-T1 227 SEYDQVLVESANENRMEESKALFRTIITYpWFQNSSIILFLNKKDLLEEKIMFSHLAE 284 55677655555554445567899988776488999*************9986665555 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.081 2.3e+02 6 35 .. 36 65 .. 31 83 .. 0.80 2 ? 8.9 0.0 0.0005 1.4 97 142 .. 232 281 .. 223 344 .. 0.69 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.081 GTP_EFTU 6 igiighvDhGKtTltdrllyktgaiskrge 35 + ++g ++GK+T++ ++ +g+ ++++ FUN_000992-T1 36 LLLLGTGESGKSTFIKQMRIIHGQGYSDED 65 567788899*******99988887666554 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0005 GTP_EFTU 97 vlvvdaveGvepqteevlrlarkl....gvpiivviNKmDrvdeaelkev 142 vlv +a+e ++++++++r + ++ + ii+++NK D+++e+ + FUN_000992-T1 232 VLVESANENRMEESKALFRTIITYpwfqNSSIILFLNKKDLLEEKIMFSH 281 89999**************999973332555***********55444444 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 5.5e-05 0.15 18 77 .. 14 77 .. 8 107 .. 0.68 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 5.5e-05 TniB 18 eilerLealleapk..kkrmpnlllvGdsnnGKstivekFarlhpaq..keedeeevpvvvvqa 77 +i +++++ l+ k + r +lll G + GKst +++ + h + +e ++ vp v+ ++ FUN_000992-T1 14 RINAEIDRQLKIDKrnQRRELKLLLLGTGESGKSTFIKQMRIIHGQGysDEDKRGYVPLVYQNI 77 55555555555444214555789*********************99842234445789888665 PP >> FtsK_SpoIIIE FtsK/SpoIIIE family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 7.7e-05 0.22 27 59 .. 19 53 .. 6 55 .. 0.78 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 7.7e-05 FtsK_SpoIIIE 27 sgnpvvldlkkmp..ghlliaGatgsGKSvalntL 59 +++ +++d ++ ll++G+ +sGKS++++ + FUN_000992-T1 19 IDRQLKIDKRNQRreLKLLLLGTGESGKSTFIKQM 53 556666666666655689*************9987 PP >> AAA_29 P-loop containing region of AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00016 0.44 24 40 .. 33 50 .. 21 59 .. 0.81 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00016 AAA_29 24 g.atlltGpsGsGKSTll 40 + + ll G+ +sGKST++ FUN_000992-T1 33 ElKLLLLGTGESGKSTFI 50 4578************98 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.0 0.003 8.4 1 19 [. 35 53 .. 35 79 .. 0.90 2 ? 2.5 0.0 0.079 2.2e+02 52 117 .. 189 269 .. 157 271 .. 0.56 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.003 Roc 1 KvvllGdsgvGKtsllkrf 19 K++llG ++ GK++++k++ FUN_000992-T1 35 KLLLLGTGESGKSTFIKQM 53 89**************975 PP == domain 2 score: 2.5 bits; conditional E-value: 0.079 Roc 52 klkkiklniWDtaGqerfr.slhplyyreaaaailvfd............srssenlkeWlkelkev..agkspvilvgnk 117 +l++i +++ D++Gq+ r + +++ + ++++lv +++ e+ k ++++ ++ ++s +il nk FUN_000992-T1 189 DLETIIFRMVDVGGQRSERrKWIHCFENVTSIMFLVALseydqvlvesanENRMEESKALFRTIITYpwFQNSSIILFLNK 269 567788999999999765415778888777777777531222444332111112223345555544433445555555565 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (353 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 717 (0.0280681); expected 510.9 (0.02) Passed bias filter: 532 (0.020826); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3446.86 // Query: FUN_000993-T1 [L=109] Description: FUN_000993 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (109 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 361 (0.0141319); expected 510.9 (0.02) Passed bias filter: 288 (0.0112742); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1083.14 // Query: FUN_000994-T1 [L=266] Description: FUN_000994 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-08 34.9 0.0 3.8e-08 34.1 0.0 1.5 1 SAM_1 SAM domain (Sterile alpha motif) 1.2e-05 25.9 0.0 1.8e-05 25.2 0.0 1.3 1 SAM_2 SAM domain (Sterile alpha motif) ------ inclusion threshold ------ 0.3 11.4 0.3 0.83 10.0 0.3 1.7 1 cIII cIII protein family Domain annotation for each model (and alignments): >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.0 4.4e-12 3.8e-08 2 53 .. 53 105 .. 52 116 .. 0.90 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 4.4e-12 SAM_1 2 gwsvedV.geWLesiglgqYadsFrkgyidgetLlqlteddLeklgvtllgHr 53 +wsv+dV +++Le glg a++F+ ++i+g++L +lte +L +lg++++g+r FUN_000994-T1 53 EWSVQDViQNFLERAGLGYMAEQFSVNKINGKCLMLLTEGHLHELGISCVGDR 105 6888887478*****************************************99 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 2.2e-09 1.8e-05 3 59 .. 53 109 .. 51 116 .. 0.87 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 2.2e-09 SAM_2 3 swslesv.aeWLrsigleqykdnFkdagitgaelllrlteedLkelGitsvghrkkil 59 ws+++v +++L++ gl+ ++++F+ ++i g + l+ lte +L elGi+ vg+r + FUN_000994-T1 53 EWSVQDViQNFLERAGLGYMAEQFSVNKING-KCLMLLTEGHLHELGISCVGDRILLS 109 5777776368*********************.*********************86654 PP >> cIII cIII protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.3 9.7e-05 0.83 13 34 .. 236 259 .. 235 262 .. 0.75 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 9.7e-05 cIII 13 AfYPh..ESELsRrvkQLIRAAkk 34 AfYPh R v QLIR A FUN_000994-T1 236 AFYPHvlRHPEARNVEQLIRNAWN 259 9***94323348********9965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (266 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 904 (0.0353885); expected 510.9 (0.02) Passed bias filter: 565 (0.0221178); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2640.05 // Query: FUN_000995-T1 [L=194] Description: FUN_000995 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-10 40.4 2.9 3e-10 40.4 2.9 2.3 3 fn2 Fibronectin type II domain ------ inclusion threshold ------ 0.011 16.4 17.0 0.011 16.4 17.0 2.0 2 UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 Domain annotation for each model (and alignments): >> fn2 Fibronectin type II domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.4 2.9 2.4e-14 3e-10 1 42 [] 30 74 .. 30 74 .. 0.92 2 ? -3.8 0.0 1.6 2e+04 14 20 .. 106 112 .. 105 116 .. 0.73 3 ? -2.4 0.1 0.57 7.2e+03 23 28 .. 131 136 .. 123 142 .. 0.70 Alignments for each domain: == domain 1 score: 40.4 bits; conditional E-value: 2.4e-14 fn2 1 CvFPFiykgksyhsCtkdgrsdgklWCattsnydkdk...kWgyC 42 C+FPF+y+g y+sC++ + + +WCat++++++ WgyC FUN_000995-T1 30 CIFPFKYNGIEYNSCVSPPKFPRIAWCATQHEFNRSVngsGWGYC 74 **********************************95444489999 PP == domain 2 score: -3.8 bits; conditional E-value: 1.6 fn2 14 sCtkdgr 20 +C++ r FUN_000995-T1 106 HCITVSR 112 6999876 PP == domain 3 score: -2.4 bits; conditional E-value: 0.57 fn2 23 gklWCa 28 +k++C+ FUN_000995-T1 131 SKPFCS 136 577787 PP >> UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.099 1.3e+03 36 47 .. 54 65 .. 35 72 .. 0.80 2 ? 16.4 17.0 8.9e-07 0.011 4 92 .. 73 166 .. 69 172 .. 0.81 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.099 UPAR_LY6_2 36 kycltvhklese 47 +c t+h+++++ FUN_000995-T1 54 AWCATQHEFNRS 65 689999999875 PP == domain 2 score: 16.4 bits; conditional E-value: 8.9e-07 UPAR_LY6_2 4 ypksfkcftcekaadnyecnrwaedkycpretkycltvhk.les..egksvsvtkkcaaleecllvg..creskeeehkectsccegnicnvel 92 y + cf c ++ +c e k c ++c+tv + +++ + +++ k ca++ c ++ c+e ++ e k cc g++cn+ + FUN_000995-T1 73 YCAGATCFECRSTISMEHCKSNLERKTCSFGVEHCITVSRqIKEsaHNITRVFKKDCASKPFCSKSNlfCNELTSGEDKCTHRCCHGELCNLAI 166 778899******************************98651443113344556778*******97654499988888888889********987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (194 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 995 (0.0389509); expected 510.9 (0.02) Passed bias filter: 380 (0.0148757); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1952.47 // Query: FUN_000996-T1 [L=130] Description: FUN_000996 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.039 15.4 21.3 0.051 15.0 21.3 1.2 1 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 21.3 2e-06 0.051 2 78 .. 22 104 .. 21 105 .. 0.69 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2e-06 Activin_recp 2 kC....y.....CetskCeedesnvtcetd.gsCfssvekettgkikvvkkgclsreqdpleCktsnkpeqlnsrieCCktdfCNkn 78 kC y C+++k +++ + tc+ Cf +v ++ t+++ +++gc+ ++++++ k+ + ++ + + +CCk++fCN++ FUN_000996-T1 22 KCfhcdYgtvsqCDPKKGNRS-TELTCTVSsNRCFRKVIRK-TDSEDEIEQGCTNEAGCNIHEKSCSGSG--DCSSYCCKENFCNND 104 663223133344666543333.5899*99999********5.555559*********9999644444444..4678*********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1278 (0.0500294); expected 510.9 (0.02) Passed bias filter: 439 (0.0171854); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1293.84 // Query: FUN_000997-T1 [L=147] Description: FUN_000997 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 HTH_psq helix-turn-helix, Psq domain Domain annotation for each model (and alignments): >> HTH_psq helix-turn-helix, Psq domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 1.2e-05 0.31 22 38 .. 53 70 .. 53 73 .. 0.89 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 1.2e-05 HTH_psq 22 AAriYgIPrsTLw.rrkr 38 A++iY+++++TL +++ FUN_000997-T1 53 ACQIYSVNYTTLKgQVLQ 70 9***********988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (147 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 991 (0.0387943); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1444.32 // Query: FUN_000998-T1 [L=164] Description: FUN_000998 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0012 19.7 13.1 0.0018 19.2 13.1 1.3 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 0.097 13.0 2.4 0.11 12.9 2.4 1.1 1 ETS_PEA3_N PEA3 subfamily ETS-domain transcription factor N 0.79 11.3 15.2 1.6 10.2 15.2 1.5 1 QVR Quiver family u-PAR/Ly-6-like domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 13.1 2.1e-07 0.0018 2 81 .. 23 98 .. 22 99 .. 0.86 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 2.1e-07 UPAR_LY6 2 glrCysClgessssccssgs..sCpkgdtqCvtttiklsgggkksslsvkgC...spscpelnetseigsltvtesccqsdlCns 81 +++Cy C+++++ +c+++++ +C Cv ++++++ ++s ++k+C + c+ ++++ ++ te+ c sd+Cn FUN_000998-T1 23 SIKCYFCQETTKAECARNQTprECNA---NCVDVELQIG---NESLAHIKDCflpGTACSIFKKHNISQ---CTETFCASDYCNG 98 689****************9999955...5******999...8899*******7777777777777776...9999********7 PP >> ETS_PEA3_N PEA3 subfamily ETS-domain transcription factor N terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 2.4 1.3e-05 0.11 106 170 .. 76 141 .. 30 156 .. 0.81 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 1.3e-05 ETS_PEA3_N 106 qslklsygekcLynasaydrkrasglksltppstP.vsPlqkssssktpPaaakasaekkekales 170 +k ++ +c ++a d + ++l+p+++P +sPl+++sss+++P+ +++++ekk++a+++ FUN_000998-T1 76 SIFKKHNISQCTETFCASDYCNGPIPSTLSPSTAPvTSPLRSESSSTENPSRSSKKPEKKQRAAAN 141 458889999**9999***9999888889999999999*************9988888877665544 PP >> QVR Quiver family u-PAR/Ly-6-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 15.2 0.00019 1.6 1 86 [] 24 97 .. 24 97 .. 0.86 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00019 QVR 1 lkCYqCnseedpeCedefdekevelkeCseeatvCvkivekeeegeerviRgCeseseedeeegckeessekkklee.CtCktdlCN 86 +kCY C+++++ eC+ +++ +eC+ Cv + + +++ i++C + c+ ++++ ++ + +C +d+CN FUN_000998-T1 24 IKCYFCQETTKAECAR-----NQTPRECN---ANCVDVELQIGNESLAHIKDC-----FLPGTACSIFKKHNISQCTeTFCASDYCN 97 89*************9.....88899***...99*******999*********.....666777877777665544437*******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1457 (0.0570366); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1630.22 // Query: FUN_000999-T1 [L=197] Description: FUN_000999 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (197 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 456 (0.0178509); expected 510.9 (0.02) Passed bias filter: 350 (0.0137013); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1940.43 // Query: FUN_001000-T1 [L=314] Description: FUN_001000 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (314 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 790 (0.0309258); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3013.66 // Query: FUN_001001-T1 [L=164] Description: FUN_001001 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0041 18.0 13.3 0.0062 17.5 13.3 1.3 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 3.3 9.3 16.0 7.1 8.2 16.0 1.6 1 QVR Quiver family u-PAR/Ly-6-like domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 13.3 4.9e-07 0.0062 2 81 .. 23 98 .. 22 99 .. 0.84 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 4.9e-07 UPAR_LY6 2 glrCysClgessssccssgs..sCpkgdtqCvtttiklsgggkksslsvkgC...spscpelnetseigsltvtesccqsdlCns 81 +++Cy C+++++ +c+++++ +C Cv ++++++ ++s ++k+C + c+ n+ + ++ te+ c sd+Cn FUN_001001-T1 23 SIKCYFCQETTKADCARKQTprECNA---NCVDVKLQIG---NESLAHIKDCflpGTACSIFNKYNISQ---CTETSCASDYCNG 98 689******99999999998889955...5*****9999...8899*******7666777666666665...9999********7 PP >> QVR Quiver family u-PAR/Ly-6-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 16.0 0.00055 7.1 1 86 [] 24 97 .. 24 97 .. 0.84 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.00055 QVR 1 lkCYqCnseedpeCedefdekevelkeCseeatvCvkivekeeegeerviRgCeseseedeeegckeessekkklee.CtCktdlCN 86 +kCY C+++++ +C+ +++ +eC+ Cv ++ + +++ i++C + c+ ++ + ++ + C +d+CN FUN_001001-T1 24 IKCYFCQETTKADCAR-----KQTPRECN---ANCVDVKLQIGNESLAHIKDC-----FLPGTACSIFNKYNISQCTeTSCASDYCN 97 89*************9.....88999***...99*******999*********.....6666777776666554433269******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1364 (0.053396); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1648.48 // Query: FUN_001002-T1 [L=282] Description: FUN_001002 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-05 24.0 37.0 0.00061 20.7 16.6 3.2 2 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 1.2 10.7 30.5 2 9.9 8.5 2.4 2 Activin_recp Activin types I and II receptor domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 16.6 4.8e-08 0.00061 2 82 .] 23 121 .. 22 121 .. 0.90 2 ! 7.5 12.4 0.00062 7.9 20 81 .. 164 244 .. 155 245 .. 0.68 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 4.8e-08 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgdtqCvtttiklsgg.gkksslsvkgC..spscpelnetseig............sltvtesccqsdlC 79 +l+Cy+C ++ + s c + s +Cp+ + +C+t+++ + ++ g+ks+l ++C + +c++ + + i+ + + +cc dlC FUN_001002-T1 23 ALKCYNCNATWAASTCLKNSrieTCPYRHPACLTVDTMVTTSkGEKSTLYLRQCipKYKCRSARPCKDIKvhllrekpdlfvDNSCQPQCCWNDLC 118 79********9999999999999************999999878************88888888777777777888999999899999******** PP UPAR_LY6 80 nsa 82 n++ FUN_001002-T1 119 NHP 121 *96 PP == domain 2 score: 7.5 bits; conditional E-value: 0.00062 UPAR_LY6 20 gssCpkgd..tqCvtttiklsgg...........gkksslsvkgC...spscpelnetseig...sltvtesccqsdlCns 81 +++C+k++ ++C+t + ++ +g + + +s+++C ++c+++++ ++ ++scc+++lCn+ FUN_001002-T1 164 EKNCSKNEqfDSCFTLRAQVVTGnmpgdvtetieWIDCAISMRDChaiTNRCTHMKHLAAHNgayLVNCSVSCCSKELCNR 244 4466333324566666666666644433323322455558999999998999998887777678899*************8 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 14.0 0.0016 21 1 77 [. 24 120 .. 24 122 .. 0.81 2 ? 9.9 8.5 0.00016 2 13 78 .. 163 245 .. 141 246 .. 0.73 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0016 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd.gsCfssveke..ttgkik.vvkkgclsreqdple..Cktsnkpeqlns.........rieCCktdfCN 76 lkCy C+ + C +++ tc + +C + + ++g+ ++ ++c++++++ Ck+ + +++ + +CC +d+CN FUN_001002-T1 24 LKCYnCNATWaastCLKNSRIETCPYRhPACLTVDTMVttSKGEKStLYLRQCIPKYKCRSArpCKDIKVHLLREKpdlfvdnscQPQCCWNDLCN 119 69*99999767888*99998999998889***9888764445555489999*****94444446999998888777999***************** PP Activin_recp 77 k 77 + FUN_001002-T1 120 H 120 8 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00016 Activin_recp 13 desnvtcetd...gsCfssvekettgkik..vvkkgclsre.qdpleCktsnkpeqlns.............rieCCktdfCNkn 78 +e +c+++ sCf+++ + tg+ v++ ++++ + C++ +++ ++ + ++ CC++++CN++ FUN_001002-T1 163 RE--KNCSKNeqfDSCFTLRAQVVTGNMPgdVTETIEWIDCaISMRDCHAITNRCTHMKhlaahngaylvncSVSCCSKELCNRA 245 33..34444445899*****99988888777777777777633333477777766665567778889****************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (282 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 938 (0.0367195); expected 510.9 (0.02) Passed bias filter: 362 (0.0141711); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2741.44 // Query: FUN_001002-T2 [L=280] Description: FUN_001002 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-05 24.0 37.1 0.00059 20.7 16.6 3.2 2 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 1.1 10.7 30.5 2 9.9 8.5 2.4 2 Activin_recp Activin types I and II receptor domain 9.1 7.6 42.8 50 5.2 12.9 3.8 2 Toxin_TOLIP Snake toxin and toxin-like protein Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 16.6 7e-08 0.00059 2 82 .] 21 119 .. 20 119 .. 0.90 2 ! 7.4 12.5 0.001 8.6 20 81 .. 162 242 .. 153 243 .. 0.68 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 7e-08 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgdtqCvtttiklsgg.gkksslsvkgC..spscpelnetseig............sltvtesccqsdlC 79 +l+Cy+C ++ + s c + s +Cp+ + +C+t+++ + ++ g+ks+l ++C + +c++ + + i+ + + +cc dlC FUN_001002-T2 21 ALKCYNCNATWAASTCLKNSrieTCPYRHPACLTVDTMVTTSkGEKSTLYLRQCipKYKCRSARPCKDIKvhllrekpdlfvDNSCQPQCCWNDLC 116 79********9999999999999************999999878************88888888777777777888999999899999******** PP UPAR_LY6 80 nsa 82 n++ FUN_001002-T2 117 NHP 119 *96 PP == domain 2 score: 7.4 bits; conditional E-value: 0.001 UPAR_LY6 20 gssCpkgd..tqCvtttiklsgg...........gkksslsvkgC...spscpelnetseig...sltvtesccqsdlCns 81 +++C+k++ ++C+t + ++ +g + + +s+++C ++c+++++ ++ ++scc+++lCn+ FUN_001002-T2 162 EKNCSKNEqfDSCFTLRAQVVTGnmpgdvtetieWIDCAISMRDChaiTNRCTHMKHLAAHNgayLVNCSVSCCSKELCNR 242 4466333324566666666666644433323322455558999999998999998887777678899*************8 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 14.0 0.0024 21 1 77 [. 22 118 .. 22 120 .. 0.81 2 ? 9.9 8.5 0.00023 2 13 78 .. 161 243 .. 139 244 .. 0.73 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0024 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd.gsCfssveke..ttgkik.vvkkgclsreqdple..Cktsnkpeqlns.........rieCCktdfCN 76 lkCy C+ + C +++ tc + +C + + ++g+ ++ ++c++++++ Ck+ + +++ + +CC +d+CN FUN_001002-T2 22 LKCYnCNATWaastCLKNSRIETCPYRhPACLTVDTMVttSKGEKStLYLRQCIPKYKCRSArpCKDIKVHLLREKpdlfvdnscQPQCCWNDLCN 117 69*99999767888*99998999998889***9888764445555489999*****94444446999998888777999***************** PP Activin_recp 77 k 77 + FUN_001002-T2 118 H 118 8 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00023 Activin_recp 13 desnvtcetd...gsCfssvekettgkik..vvkkgclsre.qdpleCktsnkpeqlns.............rieCCktdfCNkn 78 +e +c+++ sCf+++ + tg+ v++ ++++ + C++ +++ ++ + ++ CC++++CN++ FUN_001002-T2 161 RE--KNCSKNeqfDSCFTLRAQVVTGNMPgdVTETIEWIDCaISMRDCHAITNRCTHMKhlaahngaylvncSVSCCSKELCNRA 243 33..34444445899*****99988888777777777777633333477777766665567778889****************96 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 22.0 0.011 95 1 72 [] 22 117 .. 22 117 .. 0.65 2 ? 5.2 12.9 0.0059 50 19 72 .] 163 241 .. 157 241 .. 0.70 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.011 Toxin_TOLIP 1 LkCytCeeeksnsnCl...ketkCsesekyCvttvtsa...........kskkli.sksCsss..Ceessselgvas........vsvsCCqtdlC 71 LkCy+C+++ s+Cl ++++C+ ++ C+t+ t + + i + +C s C++ +++l + + +CC +dlC FUN_001002-T2 22 LKCYNCNATWAASTCLknsRIETCPYRHPACLTVDTMVttskgekstlyL-RQCIpKYKCRSArpCKDIKVHLLREKpdlfvdnsCQPQCCWNDLC 116 89*************93334689*********987777778996555531.23331334544445664444443332333333337889******* PP Toxin_TOLIP 72 N 72 N FUN_001002-T2 117 N 117 9 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0059 Toxin_TOLIP 19 tkCsesek..yCvttvtsa......................kskklisksCsssCe.essselgvasvsvsCCqtdlCN 72 ++Cs++e+ C t +++ ++ ++i+++C++ + + ++ ++ ++ svsCC+++lCN FUN_001002-T2 163 KNCSKNEQfdSCFTLRAQVvtgnmpgdvtetiewidcaismRDCHAITNRCTHMKHlAAHNGAYLVNCSVSCCSKELCN 241 6677666533477776666677777777777777777777766778999999887724444455569***********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (280 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 914 (0.03578); expected 510.9 (0.02) Passed bias filter: 341 (0.013349); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.44s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2736.28 // Query: FUN_001003-T1 [L=172] Description: FUN_001003 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0053 18.2 13.7 0.0093 17.4 13.7 1.4 1 Activin_recp Activin types I and II receptor domain ------ inclusion threshold ------ 0.51 11.3 18.5 2.3 9.2 18.5 2.0 1 UPAR_LY6 u-PAR/Ly-6 domain Domain annotation for each model (and alignments): >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 13.7 7.3e-07 0.0093 1 77 [. 5 101 .. 5 103 .. 0.83 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 7.3e-07 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd....gsCfssvekettgkik..vvkkgclsre...qdpleCktsnkpeqlns.......rieCCktdfC 75 lkCy C + C ++ s vtc+ + f+++ + t+++++ +k+c + q++l+C t+n + + + CC tdfC FUN_001003-T1 5 LKCYgCSSGAtlrdCLSNPSSVTCTDGvgfdRCTFVQMHVTTNDSQQiaYLEKECGISSicsQQALLCDTKNASFIQ-RgdvmhgcMFRCCDTDFC 99 68999877657778****9******999886667999999877777677888999888888888889*****99964.458999*9********** PP Activin_recp 76 Nk 77 N FUN_001003-T1 100 NT 101 *7 PP >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 18.5 0.00018 2.3 2 81 .. 4 101 .. 3 102 .. 0.76 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00018 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgd..tqCvtttiklsgg.gkksslsvkgC..spscpelnetseig..........sltvtesccqsdlC 79 gl+Cy C + + ++c s +C+ g + C +++++ ++ +++ + k+C s+ c++ + + + ++cc++d+C FUN_001003-T1 4 GLKCYGCSSGATLRDCLSNPssvTCTDGVgfDRCTFVQMHVTTNdSQQIAYLEKECgiSSICSQQALLCDTKnasfiqrgdvMHGCMFRCCDTDFC 99 89*****9887777776655589**66554599*********998899**********6666655443333333344568887888999******* PP UPAR_LY6 80 ns 81 n FUN_001003-T1 100 NT 101 *5 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (172 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 650 (0.0254453); expected 510.9 (0.02) Passed bias filter: 300 (0.011744); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1714.57 // Query: FUN_001004-T1 [L=157] Description: FUN_001004 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0015 19.2 10.5 0.0021 18.7 10.5 1.3 1 UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 ------ inclusion threshold ------ 0.048 14.9 21.6 0.12 13.6 21.6 1.6 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.16 12.4 4.0 0.29 11.6 4.0 1.4 1 Albumin_I_a Albumin I chain a 0.62 11.1 21.9 6.1 7.9 21.9 2.0 1 UPAR_LY6 u-PAR/Ly-6 domain Domain annotation for each model (and alignments): >> UPAR_LY6_2 Ly6/PLAUR domain-containing protein 6, Lypd6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 10.5 3.3e-07 0.0021 3 89 .. 16 114 .. 14 131 .. 0.71 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 3.3e-07 UPAR_LY6_2 3 pypksfkcftcekaadnyecnrwaedkycpretkyc..ltvhkles..egksvsvtkkcaaleecllvgcres.......keeehkec.tsccegn 86 p + + cftc + +c + +++ c ret+ c +tv + s + + + + ca++ +cl+ c+ + k++ ++ c +scc+ n FUN_001004-T1 16 PLVTPLDCFTCVSMRSMQDCVDFQKETRCLRETDQCrnMTVQVYVSmiRQNVTGYQRGCATHAQCLFKRCSGHfaekygeKSSTYNFCrMSCCQEN 111 6677789*****************************4434444333113334445578************75522112113445566745999999 PP UPAR_LY6_2 87 icn 89 +c FUN_001004-T1 112 LCP 114 995 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 21.6 1.9e-05 0.12 1 71 [. 21 113 .. 21 114 .. 0.84 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.9e-05 Toxin_TOLIP 1 LkCytCeeeksnsnCl...ketkCsesekyCvttvtsa.................kskklisksCsssCeessselgva.s.vsvsCCqtdlC 71 L C+tC + +s ++C ket+C +++++C ++++++ ++ + + k+Cs + e+ e +++ + ++sCCq++lC FUN_001004-T1 21 LDCFTCVSMRSMQDCVdfqKETRCLRETDQCRNMTVQVyvsmirqnvtgyqrgcaTHAQCLFKRCSGHFAEKYGEKSSTyNfCRMSCCQENLC 113 89*************74447889**********9999999****9999999999877888999999886665555544434599********* PP >> Albumin_I_a Albumin I chain a # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 4.0 4.5e-05 0.29 6 36 .. 74 105 .. 70 112 .. 0.88 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.5e-05 Albumin_I_a 6 cqshdecm.kkGsGkfcaryPnPeseyGWcid 36 c +h +c+ k+ sG f +y + s y +c FUN_001004-T1 74 CATHAQCLfKRCSGHFAEKYGEKSSTYNFCRM 105 99*****75889******************65 PP >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 21.9 0.00096 6.1 3 79 .. 21 113 .. 19 115 .. 0.73 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.00096 UPAR_LY6 3 lrCysClgessssccssgs...sCpkgdtqCvtttiklsgg..gkksslsvkgC..spscpelnetseig.........sltvtesccqsdlC 79 l C++C++ s ++c ++ +C ++++qC t+++ + ++++ +gC + +c ++ ++++ + sccq++lC FUN_001004-T1 21 LDCFTCVSMRSMQDCVDFQketRCLRETDQCRNMTVQVYVSmiRQNVTGYQRGCatHAQCLFKRCSGHFAekygeksstYNFCRMSCCQENLC 113 78*************9999999*********8888888888545667767788877334444333333333344454436677899******* PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1046 (0.0409473); expected 510.9 (0.02) Passed bias filter: 421 (0.0164807); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1537.88 // Query: FUN_001005-T1 [L=202] Description: FUN_001005 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (202 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 736 (0.0288119); expected 510.9 (0.02) Passed bias filter: 388 (0.0151889); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2030.40 // Query: FUN_001006-T1 [L=1897] Description: FUN_001006 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-20 72.1 1.7 3.5e-20 72.1 1.7 4.6 4 CC_CEP63-bind_CEP152 CEP152, CEP63 binding coiled coil ------ inclusion threshold ------ 4.4 7.9 6.8 64 4.1 0.4 4.9 4 DUF4287 Domain of unknown function (DUF4287) 7.3 6.9 8.0 11 6.3 1.0 5.3 3 TYRAAT1_C TYRAAT1-like, C-terminal domain Domain annotation for each model (and alignments): >> CC_CEP63-bind_CEP152 CEP152, CEP63 binding coiled coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.3 2 1.7e+04 36 49 .. 636 648 .. 633 649 .. 0.79 2 ? -1.0 3.0 0.28 2.4e+03 27 47 .. 845 865 .. 839 869 .. 0.83 3 ? -1.6 0.4 0.45 3.8e+03 4 19 .. 1463 1478 .. 1460 1490 .. 0.61 4 ! 72.1 1.7 4.2e-24 3.5e-20 1 51 [] 1525 1575 .. 1525 1575 .. 0.99 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 CC_CEP63-bind_CEP152 36 aEvlrERqetarkl 49 + l+E q+ a ++ FUN_001006-T1 636 SQ-LKEQQTKAHRM 648 55.89****99998 PP == domain 2 score: -1.0 bits; conditional E-value: 0.28 CC_CEP63-bind_CEP152 27 rerAAetvkaEvlrERqetar 47 re A+ + Ev++E+++ ++ FUN_001006-T1 845 REEEAQRIEDEVMKEKEKLLK 865 7778999*********98776 PP == domain 3 score: -1.6 bits; conditional E-value: 0.45 CC_CEP63-bind_CEP152 4 LraqYlktVeKIkdDv 19 +++ Y +++eK+k+ + FUN_001006-T1 1463 MKKEYGMVIEKLKREL 1478 6666666666666543 PP == domain 4 score: 72.1 bits; conditional E-value: 4.2e-24 CC_CEP63-bind_CEP152 1 LeeLraqYlktVeKIkdDvlryiqesrerAAetvkaEvlrERqetarklrk 51 LeeLr +Yl+t++KI++Dvl+++++++ AA+ +++Ev +ER++ta+klrk FUN_001006-T1 1525 LEELRGHYLDTIAKIRNDVLDHVNQTKASAAKKIRSEVSKERHSTAKKLRK 1575 89***********************************************97 PP >> DUF4287 Domain of unknown function (DUF4287) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.034 2.9e+02 23 50 .. 109 136 .. 106 138 .. 0.80 2 ? -0.0 0.1 0.15 1.3e+03 27 43 .. 757 773 .. 749 775 .. 0.76 3 ? 4.1 0.4 0.0075 64 18 45 .. 1173 1199 .. 1171 1201 .. 0.94 4 ? -2.2 0.1 0.71 6e+03 6 33 .. 1460 1487 .. 1456 1488 .. 0.70 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.034 DUF4287 23 lveeggllvkhgervawLkeehgLghGh 50 l++ +g + + erva L ++++L h++ FUN_001006-T1 109 LMNGSGQSGNSHERVASLPQDYDLDHCY 136 555555555778**************98 PP == domain 2 score: -0.0 bits; conditional E-value: 0.15 DUF4287 27 ggllvkhgervawLkee 43 ++l h+e+v Lk+e FUN_001006-T1 757 HQLNQEHEEIVRALKKE 773 444458*********99 PP == domain 3 score: 4.1 bits; conditional E-value: 0.0075 DUF4287 18 aeWlalveeggllvkhgervawLkeehg 45 + W++ +ee++ + + e va+L +e+ FUN_001006-T1 1173 EAWVEEAEEQKRE-EVNEAVAYLEAEYA 1199 57***********.************95 PP == domain 4 score: -2.2 bits; conditional E-value: 0.71 DUF4287 6 ldniekkTGkplaeWlalveeggllvkh 33 l++++k++G ++ + + + e++ +kh FUN_001006-T1 1460 LATMKKEYGMVIEKLKRELVEERKKSKH 1487 6788999999999987655544444476 PP >> TYRAAT1_C TYRAAT1-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 1.0 0.0013 11 42 72 .. 617 647 .. 614 650 .. 0.86 2 ? -2.8 0.5 0.9 7.7e+03 50 73 .. 1273 1296 .. 1268 1298 .. 0.76 3 ? -1.0 0.0 0.25 2.1e+03 7 18 .. 1732 1743 .. 1728 1749 .. 0.88 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0013 TYRAAT1_C 42 NknakeelekLelalekvkkkLfkrlheelr 72 Nk +e+ + Le+ l++vk++L++++++ r FUN_001006-T1 617 NKGKREQVQSLEKELTSVKSQLKEQQTKAHR 647 777799*******************987665 PP == domain 2 score: -2.8 bits; conditional E-value: 0.9 TYRAAT1_C 50 ekLelalekvkkkLfkrlheelrk 73 e+L++ ++v+k+L ++l+ + ++ FUN_001006-T1 1273 EELDNCASQVEKSLREKLQAKHDE 1296 788888899999999999866555 PP == domain 3 score: -1.0 bits; conditional E-value: 0.25 TYRAAT1_C 7 lestpidTkGye 18 e+tpi+Tk y+ FUN_001006-T1 1732 SEETPIETKAYH 1743 589******996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1897 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4587 (0.179565); expected 510.9 (0.02) Passed bias filter: 618 (0.0241926); expected 510.9 (0.02) Passed Vit filter: 207 (0.00810335); expected 25.5 (0.001) Passed Fwd filter: 46 (0.00180074); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 1.34u 0.44s 00:00:01.78 Elapsed: 00:00:00.56 # Mc/sec: 13748.73 // Query: FUN_001006-T2 [L=1631] Description: FUN_001006 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-20 72.3 1.7 3e-20 72.3 1.7 4.8 5 CC_CEP63-bind_CEP152 CEP152, CEP63 binding coiled coil ------ inclusion threshold ------ 0.14 12.4 0.7 0.73 10.1 0.7 2.3 1 DUF1796 Putative papain-like cysteine peptidase Domain annotation for each model (and alignments): >> CC_CEP63-bind_CEP152 CEP152, CEP63 binding coiled coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.3 1.1 1.5e+04 36 49 .. 636 648 .. 633 649 .. 0.79 2 ? -3.5 0.2 1.1 1.5e+04 28 51 .] 749 772 .. 748 772 .. 0.84 3 ? -0.8 3.0 0.16 2e+03 27 47 .. 845 865 .. 839 869 .. 0.83 4 ? -1.4 0.4 0.25 3.2e+03 4 19 .. 1463 1478 .. 1460 1490 .. 0.61 5 ! 72.3 1.7 2.3e-24 3e-20 1 51 [] 1525 1575 .. 1525 1575 .. 0.99 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 1.1 CC_CEP63-bind_CEP152 36 aEvlrERqetarkl 49 + l+E q+ a ++ FUN_001006-T2 636 SQ-LKEQQTKAHRM 648 55.89****99998 PP == domain 2 score: -3.5 bits; conditional E-value: 1.1 CC_CEP63-bind_CEP152 28 erAAetvkaEvlrERqetarklrk 51 e A + +k + +E +e r l+k FUN_001006-T2 749 EDAKNLLKHQLNQEHEEIVRALKK 772 568899999999999999998875 PP == domain 3 score: -0.8 bits; conditional E-value: 0.16 CC_CEP63-bind_CEP152 27 rerAAetvkaEvlrERqetar 47 re A+ + Ev++E+++ ++ FUN_001006-T2 845 REEEAQRIEDEVMKEKEKLLK 865 7778999*********98776 PP == domain 4 score: -1.4 bits; conditional E-value: 0.25 CC_CEP63-bind_CEP152 4 LraqYlktVeKIkdDv 19 +++ Y +++eK+k+ + FUN_001006-T2 1463 MKKEYGMVIEKLKREL 1478 6666666666666543 PP == domain 5 score: 72.3 bits; conditional E-value: 2.3e-24 CC_CEP63-bind_CEP152 1 LeeLraqYlktVeKIkdDvlryiqesrerAAetvkaEvlrERqetarklrk 51 LeeLr +Yl+t++KI++Dvl+++++++ AA+ +++Ev +ER++ta+klrk FUN_001006-T2 1525 LEELRGHYLDTIAKIRNDVLDHVNQTKASAAKKIRSEVSKERHSTAKKLRK 1575 89***********************************************97 PP >> DUF1796 Putative papain-like cysteine peptidase (DUF1796) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.7 5.7e-05 0.73 30 134 .. 1140 1244 .. 1132 1273 .. 0.87 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 5.7e-05 DUF1796 30 wvrcsldgllelirngFdsflkpenlevegssskaavkeedpfipeavkvwllfrdqhtcfahfdlnypevkakfkrrfdrfeellsspekpvt 123 r+ +++l e i n F++ k+e +e + +a v+e+++++ e+v+ + + + ++ + +++ +e+k+ +++ +++ + s ++++ FUN_001006-T2 1140 QKRSEMESLREQIFNEFEEQKKVEIMETLEEAKEAWVEEAEEQKREEVNEAVAYLEAEYAKSLDEFKHKELKETLDQARKQWTAEELSHREEIV 1233 56889999******************88888888889999******************************************977666668999 PP DUF1796 124 FiRtviaedea 134 R + a+++ FUN_001006-T2 1234 EARLSAAREDW 1244 88888887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1631 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5249 (0.205481); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 227 (0.00888628); expected 25.5 (0.001) Passed Fwd filter: 55 (0.00215306); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 1.44u 0.45s 00:00:01.89 Elapsed: 00:00:00.58 # Mc/sec: 11407.69 // Query: FUN_001006-T3 [L=1414] Description: FUN_001006 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.017 15.6 0.2 0.095 13.3 0.2 2.3 1 DUF7636 Domain of unknown function (DUF7636) 0.021 15.2 1.1 0.021 15.2 1.1 5.2 5 UvrA_inter UvrA interaction domain 0.1 12.9 0.6 0.53 10.6 0.6 2.3 1 DUF1796 Putative papain-like cysteine peptidase (DUF1796) Domain annotation for each model (and alignments): >> DUF7636 Domain of unknown function (DUF7636) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.2 1.1e-05 0.095 44 90 .. 607 654 .. 568 662 .. 0.78 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.1e-05 DUF7636 44 kkktvrviVsavGtleslqkLr.klltvkpplnseanlkerseqlarl 90 k+ +++++s +G e++q L+ +l +vk +l++++++ +r+e++a++ FUN_001006-T3 607 RKELEQCLISNKGKREQVQSLEkELTSVKSQLKEQQTKAHRMEMIAQE 654 56778999*************626889******************987 PP >> UvrA_inter UvrA interaction domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.3 0.55 4.6e+03 51 87 .. 628 664 .. 606 671 .. 0.84 2 ? -1.3 0.2 0.34 2.9e+03 9 68 .. 743 803 .. 736 831 .. 0.75 3 ? -1.3 0.1 0.33 2.8e+03 66 92 .. 830 856 .. 813 860 .. 0.84 4 ? -0.9 0.1 0.24 2e+03 80 99 .. 951 970 .. 919 980 .. 0.61 5 ? 15.2 1.1 2.4e-06 0.021 42 101 .. 1011 1070 .. 991 1077 .. 0.86 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.55 UvrA_inter 51 dgeiveldeepkldknkkhtievvvdrlvikeeersr 87 + e+++++ + k ++ k h++e++ + ++k++e +r FUN_001006-T3 628 EKELTSVKSQLKEQQTKAHRMEMIAQEHEVKSQELER 664 5678888889999999999999999999998876554 PP == domain 2 score: -1.3 bits; conditional E-value: 0.34 UvrA_inter 9 kilklpegtkllilAPvvrgrkgehkelleklkkeGfvRvridgeiveldeepk.ldknkk 68 l+l+e+ k l+ + ++ ++ ++ l ++l+ +G +ri + +v+l+ee + l+++ k FUN_001006-T3 743 ACLQLHEDAKNLLKHQLNQEHEEIVRALKKELEDNGEELLRIKECYVQLSEESRvLEQRLK 803 5667777777777777777888888888889999999999999999999985541555545 PP == domain 3 score: -1.3 bits; conditional E-value: 0.33 UvrA_inter 66 nkkhtievvvdrlvikeeersrlaesv 92 +++ht +++ +r +++eee++r+ + v FUN_001006-T3 830 QQQHTEQLIKEREQWREEEAQRIEDEV 856 578888899999999999999999987 PP == domain 4 score: -0.9 bits; conditional E-value: 0.24 UvrA_inter 80 ikeeersrlaesvetAlklg 99 ke++ + ++++ve+Al+++ FUN_001006-T3 951 YKESRGHHINQAVELALSHA 970 23334477888888888766 PP == domain 5 score: 15.2 bits; conditional E-value: 2.4e-06 UvrA_inter 42 keGfvRvridgeiveldeepkldknkkhtievvvdrlvikeeersrlaesvetAlklgkG 101 +++ ++ + +e ++ ++e +l++ k + +v v ++++ eee+++++e++e+Al+++++ FUN_001006-T3 1011 QDNLLQAALAQERRRWQKEVELERIKAAEAAVAVAEVKWLEEEERKISEAIEQALQVARD 1070 566777778888899999**************************************9987 PP >> DUF1796 Putative papain-like cysteine peptidase (DUF1796) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.6 6.2e-05 0.53 30 134 .. 1140 1244 .. 1131 1276 .. 0.87 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 6.2e-05 DUF1796 30 wvrcsldgllelirngFdsflkpenlevegssskaavkeedpfipeavkvwllfrdqhtcfahfdlnypevkakfkrrfdrfeellsspekpvt 123 r+ +++l e i n F++ k+e +e + +a v+e+++++ e+v+ + + + ++ + +++ +e+k+ +++ +++ + s ++++ FUN_001006-T3 1140 QKRSEMESLREQIFNEFEEQKKVEIMETLEEAKEAWVEEAEEQKREEVNEAVAYLEAEYAKSLDEFKHKELKETLDQARKQWTAEELSHREEIV 1233 56889999******************88888888889999******************************************977666668999 PP DUF1796 124 FiRtviaedea 134 R + a+++ FUN_001006-T3 1234 EARLSAAREDW 1244 88888887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1414 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4454 (0.174359); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 194 (0.00759444); expected 25.5 (0.001) Passed Fwd filter: 48 (0.00187904); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 1.14u 0.42s 00:00:01.55 Elapsed: 00:00:00.53 # Mc/sec: 10737.21 // Query: FUN_001006-T4 [L=1630] Description: FUN_001006 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-20 72.3 1.7 3e-20 72.3 1.7 4.8 5 CC_CEP63-bind_CEP152 CEP152, CEP63 binding coiled coil ------ inclusion threshold ------ 0.14 12.4 0.7 0.72 10.1 0.7 2.3 1 DUF1796 Putative papain-like cysteine peptidase Domain annotation for each model (and alignments): >> CC_CEP63-bind_CEP152 CEP152, CEP63 binding coiled coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.3 1.1 1.5e+04 36 49 .. 636 648 .. 633 649 .. 0.79 2 ? -3.5 0.2 1.1 1.5e+04 28 51 .] 749 772 .. 748 772 .. 0.84 3 ? -0.8 3.0 0.16 2e+03 27 47 .. 845 865 .. 839 869 .. 0.83 4 ? -1.4 0.4 0.25 3.2e+03 4 19 .. 1463 1478 .. 1460 1490 .. 0.61 5 ! 72.3 1.7 2.3e-24 3e-20 1 51 [] 1525 1575 .. 1525 1575 .. 0.99 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 1.1 CC_CEP63-bind_CEP152 36 aEvlrERqetarkl 49 + l+E q+ a ++ FUN_001006-T4 636 SQ-LKEQQTKAHRM 648 55.89****99998 PP == domain 2 score: -3.5 bits; conditional E-value: 1.1 CC_CEP63-bind_CEP152 28 erAAetvkaEvlrERqetarklrk 51 e A + +k + +E +e r l+k FUN_001006-T4 749 EDAKNLLKHQLNQEHEEIVRALKK 772 568899999999999999998875 PP == domain 3 score: -0.8 bits; conditional E-value: 0.16 CC_CEP63-bind_CEP152 27 rerAAetvkaEvlrERqetar 47 re A+ + Ev++E+++ ++ FUN_001006-T4 845 REEEAQRIEDEVMKEKEKLLK 865 7778999*********98776 PP == domain 4 score: -1.4 bits; conditional E-value: 0.25 CC_CEP63-bind_CEP152 4 LraqYlktVeKIkdDv 19 +++ Y +++eK+k+ + FUN_001006-T4 1463 MKKEYGMVIEKLKREL 1478 6666666666666543 PP == domain 5 score: 72.3 bits; conditional E-value: 2.3e-24 CC_CEP63-bind_CEP152 1 LeeLraqYlktVeKIkdDvlryiqesrerAAetvkaEvlrERqetarklrk 51 LeeLr +Yl+t++KI++Dvl+++++++ AA+ +++Ev +ER++ta+klrk FUN_001006-T4 1525 LEELRGHYLDTIAKIRNDVLDHVNQTKASAAKKIRSEVSKERHSTAKKLRK 1575 89***********************************************97 PP >> DUF1796 Putative papain-like cysteine peptidase (DUF1796) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.7 5.7e-05 0.72 30 134 .. 1140 1244 .. 1132 1273 .. 0.87 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 5.7e-05 DUF1796 30 wvrcsldgllelirngFdsflkpenlevegssskaavkeedpfipeavkvwllfrdqhtcfahfdlnypevkakfkrrfdrfeellsspekpvt 123 r+ +++l e i n F++ k+e +e + +a v+e+++++ e+v+ + + + ++ + +++ +e+k+ +++ +++ + s ++++ FUN_001006-T4 1140 QKRSEMESLREQIFNEFEEQKKVEIMETLEEAKEAWVEEAEEQKREEVNEAVAYLEAEYAKSLDEFKHKELKETLDQARKQWTAEELSHREEIV 1233 56889999******************88888888889999******************************************977666668999 PP DUF1796 124 FiRtviaedea 134 R + a+++ FUN_001006-T4 1234 EARLSAAREDW 1244 88888887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1630 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5245 (0.205324); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 226 (0.00884713); expected 25.5 (0.001) Passed Fwd filter: 55 (0.00215306); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 1.42u 0.47s 00:00:01.89 Elapsed: 00:00:00.57 # Mc/sec: 11644.30 // Query: FUN_001007-T1 [L=308] Description: FUN_001007 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (308 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 657 (0.0257193); expected 510.9 (0.02) Passed bias filter: 370 (0.0144842); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3010.38 // Query: FUN_001008-T1 [L=870] Description: FUN_001008 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-22 80.0 3.4 7.6e-09 36.5 0.0 2.7 3 Ank_2 Ankyrin repeats (3 copies) 4.5e-16 59.1 2.9 6.5e-05 23.6 0.1 4.5 4 Ank_4 Ankyrin repeats (many copies) 5.9e-14 52.5 0.1 0.00015 22.5 0.0 3.6 3 Ank_5 Ankyrin repeats (many copies) 2.2e-10 40.7 2.3 0.024 15.5 0.0 4.6 5 Ank Ankyrin repeat 5.4e-10 39.0 0.0 0.14 13.3 0.0 4.4 4 Ank_3 Ankyrin repeat ------ inclusion threshold ------ 0.082 13.2 1.0 0.2 12.0 1.0 1.6 1 CCDC92 Coiled-coil domain of unknown function 0.2 12.1 3.9 0.23 11.9 0.3 2.8 3 CtIP_N Tumour-suppressor protein CtIP N-terminal domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 0.1 1.9e-10 7e-07 23 82 .. 210 274 .. 194 283 .. 0.81 2 ! 30.2 0.2 2e-10 7.3e-07 1 82 [. 220 309 .. 220 316 .. 0.81 3 ! 36.5 0.0 2.1e-12 7.6e-09 2 81 .. 292 378 .. 291 384 .. 0.81 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 1.9e-10 Ank_2 23 nlqdkngetaLhlAaknghleivklLle...hgad..vn..dnngrtaLhyAaesghleivklLlek 82 +++d +g+taLh Aa++g+l ++++L++ + d n + ++ + L +A+++g+++++ +Lle+ FUN_001008-T1 210 RITDAFGNTALHKAAEAGSLSTLQWLVSrlpN--DclGNitNGENLSLLAVAVKYGSVQCIDWLLEE 274 567789*********************95553..122334348899999****************65 PP == domain 2 score: 30.2 bits; conditional E-value: 2e-10 Ank_2 1 LmlAakngnlelvklLl....egadanlqdkngetaLhlAaknghleivklLlehgadvn...dnngrtaL.hyAaesghleivklLlek 82 L+ Aa+ g+l+++++L+ +++ n+++ ++ + L +A+k+g+++++ +Lle+ +++ + r+aL h A+++ + ++ Ll + FUN_001008-T1 220 LHKAAEAGSLSTLQWLVsrlpNDCLGNITNGENLSLLAVAVKYGSVQCIDWLLEETSAADeisNLASRSALiHEAIQHEQDGSLRCLLAY 309 89***************7643334446777799********************975334445557799***9******999999999854 PP == domain 3 score: 36.5 bits; conditional E-value: 2.1e-12 Ank_2 2 mlAakngnlelvklLl.....egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 + A+++++ ++ Ll ++ + +++d+ g t h+Aa+ g++ ++++L++h++dv d++gr++ yA g+ + ++L+ FUN_001008-T1 292 HEAIQHEQDGSLRCLLayirdKHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTseDKDGRSPADYAYAAGQTSCGRYLVM 378 7888854444555554433677788888888************************87776899**********************94 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 3.8e-07 0.0014 23 50 .] 209 236 .. 186 236 .. 0.80 2 ! 23.6 0.1 1.8e-08 6.5e-05 1 50 [] 220 272 .. 220 272 .. 0.95 3 ! 19.5 0.1 3.6e-07 0.0013 2 50 .] 292 344 .. 291 344 .. 0.84 4 ! 19.9 0.0 2.6e-07 0.00094 2 49 .. 329 376 .. 328 377 .. 0.90 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 3.8e-07 Ank_4 23 inatdgngetaLhfAasngnlevlklLl 50 + td +g+taLh+Aa g+l+ l++L+ FUN_001008-T1 209 VRITDAFGNTALHKAAEAGSLSTLQWLV 236 556799********************96 PP == domain 2 score: 23.6 bits; conditional E-value: 1.8e-08 Ank_4 1 lhaAaksghlellklLlengad...inatdgngetaLhfAasngnlevlklLl 50 lh+Aa++g l +l++L++ ++ n t+g+ + L A++ g+++++ +Ll FUN_001008-T1 220 LHKAAEAGSLSTLQWLVSRLPNdclGNITNGENLSLLAVAVKYGSVQCIDWLL 272 8****************987777989999***********************8 PP == domain 3 score: 19.5 bits; conditional E-value: 3.6e-07 Ank_4 2 haAak...sghlel.lklLlengadinatdgngetaLhfAasngnlevlklLl 50 h A+ +g l++ l ++ ++ ++++ td +g t h Aa+ g++++l+ L+ FUN_001008-T1 292 HEAIQheqDGSLRClLAYIRDKHLELDVTDSSGVTLAHVAAREGQISCLQALV 344 66666666788888455777******************************995 PP == domain 4 score: 19.9 bits; conditional E-value: 2.6e-07 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 h+Aa +g++ +l+ L+++ +d+ d++g+++ ++A + g++++ ++L FUN_001008-T1 329 HVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYAYAAGQTSCGRYL 376 99****************8886666***************99997777 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 3.6e-07 0.0013 11 56 .] 211 259 .. 208 259 .. 0.92 2 ! 11.9 0.0 9e-05 0.33 9 37 .. 245 273 .. 241 285 .. 0.87 3 ! 22.5 0.0 4.2e-08 0.00015 5 56 .] 312 364 .. 310 364 .. 0.95 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 3.6e-07 Ank_5 11 rldgegytpLhvAakygaleivrlLl...angvdlnlkdeegltpldlA 56 ++d +g+t+Lh+Aa++g+l +++L+ n++ n+++ e+l++l +A FUN_001008-T1 211 ITDAFGNTALHKAAEAGSLSTLQWLVsrlPNDCLGNITNGENLSLLAVA 259 67889**********************999************9998766 PP == domain 2 score: 11.9 bits; conditional E-value: 9e-05 Ank_5 9 lnrldgegytpLhvAakygaleivrlLla 37 n+++ge L vA+kyg+ +++ +Ll+ FUN_001008-T1 245 GNITNGENLSLLAVAVKYGSVQCIDWLLE 273 4999************************3 PP == domain 3 score: 22.5 bits; conditional E-value: 4.2e-08 Ank_5 5 g.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + ++ l+ +d g+t hvAa+ g +++ L++++ d++ d++g +p d+A FUN_001008-T1 312 DkHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYA 364 44788999********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 6.5e-06 0.024 2 23 .. 216 237 .. 215 247 .. 0.90 2 ! 6.8 0.0 0.0039 14 5 24 .. 255 274 .. 251 283 .. 0.77 3 ? -3.8 0.1 7 2.6e+04 6 22 .. 291 307 .. 290 309 .. 0.74 4 ! 14.1 0.0 1.8e-05 0.067 2 33 .] 324 355 .. 323 355 .. 0.89 5 ? -0.0 0.0 0.56 2e+03 1 22 [. 356 377 .. 356 384 .. 0.86 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6.5e-06 Ank 2 GnTPLHlAaraghlevvklLLk 23 GnT+LH Aa+ag+l+++++L++ FUN_001008-T1 216 GNTALHKAAEAGSLSTLQWLVS 237 9*******************94 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0039 Ank 5 PLHlAaraghlevvklLLkh 24 L +A+++g+++++ +LL++ FUN_001008-T1 255 LLAVAVKYGSVQCIDWLLEE 274 566899************54 PP == domain 3 score: -3.8 bits; conditional E-value: 7 Ank 6 LHlAaraghlevvklLL 22 +H A+++ + ++ LL FUN_001008-T1 291 IHEAIQHEQDGSLRCLL 307 69999777777777777 PP == domain 4 score: 14.1 bits; conditional E-value: 1.8e-05 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G T H+Aar+g++++++ L++h+ dv dk FUN_001008-T1 324 GVTLAHVAAREGQISCLQALVDHNIDVTSEDK 355 77889****************88999988775 PP == domain 5 score: -0.0 bits; conditional E-value: 0.56 Ank 1 dGnTPLHlAaraghlevvklLL 22 dG++P +A ag++++ ++L+ FUN_001008-T1 356 DGRSPADYAYAAGQTSCGRYLV 377 799999999999*****99998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.0 3.9e-05 0.14 1 28 [. 215 242 .. 215 244 .. 0.89 2 ! 8.8 0.0 0.0011 4.1 2 24 .. 252 274 .. 251 279 .. 0.87 3 ! 11.5 0.0 0.00015 0.56 2 29 .. 324 350 .. 323 352 .. 0.93 4 ? -2.1 0.0 4.2 1.5e+04 1 23 [. 356 378 .. 356 382 .. 0.82 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 3.9e-05 Ank_3 1 dgntpLhlAarngrleivklLleklgad 28 +gnt+Lh Aa+ g+l +++L+ +l+ d FUN_001008-T1 215 FGNTALHKAAEAGSLSTLQWLVSRLPND 242 59*************99****9977666 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0011 Ank_3 2 gntpLhlAarngrleivklLlek 24 + ++L +A+++g+++ +++Lle+ FUN_001008-T1 252 NLSLLAVAVKYGSVQCIDWLLEE 274 568999***************94 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00015 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g t+ h+Aar g++ +++L++ +++d+ FUN_001008-T1 324 GVTLAHVAAREGQISCLQALVD-HNIDV 350 789*******************.99997 PP == domain 4 score: -2.1 bits; conditional E-value: 4.2 Ank_3 1 dgntpLhlAarngrleivklLle 23 dg++p +A g+ ++L+ FUN_001008-T1 356 DGRSPADYAYAAGQTSCGRYLVM 378 69999999999998888888875 PP >> CCDC92 Coiled-coil domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 1.0 5.6e-05 0.2 24 49 .. 391 416 .. 389 420 .. 0.88 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.6e-05 CCDC92 24 gLHkEIerLqkrnkdLtfklvmkege 49 +LH E+++ + +nkdL +kl++ e + FUN_001008-T1 391 KLHRELKECKDENKDLRQKLEVLENQ 416 8*******************987765 PP >> CtIP_N Tumour-suppressor protein CtIP N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.52 1.9e+03 59 91 .. 59 91 .. 48 113 .. 0.72 2 ? 11.9 0.3 6.2e-05 0.23 36 76 .. 388 428 .. 378 444 .. 0.87 3 ? -2.9 0.1 2.4 8.8e+03 64 78 .. 794 808 .. 793 810 .. 0.82 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.52 CtIP_N 59 kvLEnrLraglCdrCavtqellkkkqqefessq 91 LE+ L+a + + v++e++ ++ +f++ + FUN_001008-T1 59 LYLEECLKALDGNAHEVQEEEIDLEEYDFDDYN 91 469999999999999999999999999888753 PP == domain 2 score: 11.9 bits; conditional E-value: 6.2e-05 CtIP_N 36 rleelfsknqqlrEqqkvlkenikvLEnrLraglCdrCavt 76 r+ +l+ ++ ++++k l+++++vLEn+ r+gl +r v FUN_001008-T1 388 RIAKLHRELKECKDENKDLRQKLEVLENQTRTGLPNRPEVV 428 889999999*************************9998775 PP == domain 3 score: -2.9 bits; conditional E-value: 2.4 CtIP_N 64 rLraglCdrCavtqe 78 rL ++Cdr ++ ++ FUN_001008-T1 794 RLTGSECDRTMLRDN 808 78899****998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (870 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1025 (0.0401253); expected 510.9 (0.02) Passed bias filter: 550 (0.0215306); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.39u 0.43s 00:00:00.82 Elapsed: 00:00:00.43 # Mc/sec: 8248.75 // Query: FUN_001008-T2 [L=605] Description: FUN_001008 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-23 82.9 3.7 4.5e-09 37.2 0.0 2.8 3 Ank_2 Ankyrin repeats (3 copies) 8.8e-16 58.1 0.2 0.00059 20.6 0.0 4.5 4 Ank_4 Ankyrin repeats (many copies) 1.5e-14 54.4 0.2 9.6e-05 23.2 0.0 3.7 3 Ank_5 Ankyrin repeats (many copies) 5.5e-11 42.6 2.8 0.016 16.1 0.0 4.7 5 Ank Ankyrin repeat 1.3e-10 40.9 0.2 0.091 13.9 0.0 4.5 5 Ank_3 Ankyrin repeat ------ inclusion threshold ------ 0.019 15.4 1.1 0.14 12.6 0.3 2.6 2 CtIP_N Tumour-suppressor protein CtIP N-terminal d 0.054 13.8 1.0 0.13 12.6 1.0 1.6 1 CCDC92 Coiled-coil domain of unknown function 0.15 11.8 0.1 0.28 11.0 0.1 1.3 1 TPR_NUP160_120_M NUP160/120 middle TPR Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.0 1.3e-10 4.2e-07 23 82 .. 210 274 .. 189 282 .. 0.81 2 ! 30.8 0.3 1.4e-10 4.5e-07 1 82 [. 220 309 .. 220 316 .. 0.81 3 ! 37.2 0.0 1.4e-12 4.5e-09 2 81 .. 292 378 .. 291 384 .. 0.81 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 1.3e-10 Ank_2 23 nlqdkngetaLhlAaknghleivklLle...hgad..vn..dnngrtaLhyAaesghleivklLlek 82 +++d +g+taLh Aa++g+l ++++L++ + d n + ++ + L +A+++g+++++ +Lle+ FUN_001008-T2 210 RITDAFGNTALHKAAEAGSLSTLQWLVSrlpN--DclGNitNGENLSLLAVAVKYGSVQCIDWLLEE 274 567789*********************95553..122334348899999****************75 PP == domain 2 score: 30.8 bits; conditional E-value: 1.4e-10 Ank_2 1 LmlAakngnlelvklLl....egadanlqdkngetaLhlAaknghleivklLlehgadvn...dnngrtaL.hyAaesghleivklLlek 82 L+ Aa+ g+l+++++L+ +++ n+++ ++ + L +A+k+g+++++ +Lle+ +++ + r+aL h A+++ + ++ Ll + FUN_001008-T2 220 LHKAAEAGSLSTLQWLVsrlpNDCLGNITNGENLSLLAVAVKYGSVQCIDWLLEETSAADeisNLASRSALiHEAIQHEQDGSLRCLLAY 309 89***************7643334446777799********************975334445557799***9******999999999854 PP == domain 3 score: 37.2 bits; conditional E-value: 1.4e-12 Ank_2 2 mlAakngnlelvklLl.....egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 + A+++++ ++ Ll ++ + +++d+ g t h+Aa+ g++ ++++L++h++dv d++gr++ yA g+ + ++L+ FUN_001008-T2 292 HEAIQHEQDGSLRCLLayirdKHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTseDKDGRSPADYAYAAGQTSCGRYLVM 378 7888854444555555433677788888888************************87776899**********************94 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 2.8e-07 0.00089 23 50 .] 209 236 .. 186 236 .. 0.80 2 ! 7.1 0.0 0.0032 10 24 50 .] 246 272 .. 237 278 .. 0.88 3 ! 20.1 0.1 2.6e-07 0.00083 2 50 .] 292 344 .. 291 344 .. 0.84 4 ! 20.6 0.0 1.9e-07 0.00059 2 49 .. 329 376 .. 328 377 .. 0.90 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 2.8e-07 Ank_4 23 inatdgngetaLhfAasngnlevlklLl 50 + td +g+taLh+Aa g+l+ l++L+ FUN_001008-T2 209 VRITDAFGNTALHKAAEAGSLSTLQWLV 236 556799********************96 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0032 Ank_4 24 natdgngetaLhfAasngnlevlklLl 50 n t+g+ + L A++ g+++++ +Ll FUN_001008-T2 246 NITNGENLSLLAVAVKYGSVQCIDWLL 272 677888999999999999999999997 PP == domain 3 score: 20.1 bits; conditional E-value: 2.6e-07 Ank_4 2 haAak...sghlel.lklLlengadinatdgngetaLhfAasngnlevlklLl 50 h A+ +g l++ l ++ ++ ++++ td +g t h Aa+ g++++l+ L+ FUN_001008-T2 292 HEAIQheqDGSLRClLAYIRDKHLELDVTDSSGVTLAHVAAREGQISCLQALV 344 66666666788888455777******************************995 PP == domain 4 score: 20.6 bits; conditional E-value: 1.9e-07 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 h+Aa +g++ +l+ L+++ +d+ d++g+++ ++A + g++++ ++L FUN_001008-T2 329 HVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYAYAAGQTSCGRYL 376 99****************8886666***************99997777 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 9.4e-07 0.003 11 53 .. 211 256 .. 208 256 .. 0.90 2 ! 12.6 0.0 6.4e-05 0.2 9 37 .. 245 273 .. 239 285 .. 0.87 3 ! 23.2 0.0 3e-08 9.6e-05 5 56 .] 312 364 .. 310 364 .. 0.95 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 9.4e-07 Ank_5 11 rldgegytpLhvAakygaleivrlLl...angvdlnlkdeegltpl 53 ++d +g+t+Lh+Aa++g+l +++L+ n++ n+++ e+l++l FUN_001008-T2 211 ITDAFGNTALHKAAEAGSLSTLQWLVsrlPNDCLGNITNGENLSLL 256 67889**********************9999999999999998765 PP == domain 2 score: 12.6 bits; conditional E-value: 6.4e-05 Ank_5 9 lnrldgegytpLhvAakygaleivrlLla 37 n+++ge L vA+kyg+ +++ +Ll+ FUN_001008-T2 245 GNITNGENLSLLAVAVKYGSVQCIDWLLE 273 599*************************3 PP == domain 3 score: 23.2 bits; conditional E-value: 3e-08 Ank_5 5 g.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + ++ l+ +d g+t hvAa+ g +++ L++++ d++ d++g +p d+A FUN_001008-T2 312 DkHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYA 364 44788999********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 4.9e-06 0.016 2 23 .. 216 237 .. 215 247 .. 0.90 2 ! 7.3 0.0 0.0029 9.2 5 24 .. 255 274 .. 251 283 .. 0.77 3 ? -3.2 0.1 6.6 2.1e+04 6 22 .. 291 307 .. 290 309 .. 0.74 4 ! 14.7 0.0 1.4e-05 0.043 2 33 .] 324 355 .. 323 355 .. 0.89 5 ? 0.6 0.0 0.4 1.3e+03 1 22 [. 356 377 .. 356 385 .. 0.86 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 4.9e-06 Ank 2 GnTPLHlAaraghlevvklLLk 23 GnT+LH Aa+ag+l+++++L++ FUN_001008-T2 216 GNTALHKAAEAGSLSTLQWLVS 237 9*******************94 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0029 Ank 5 PLHlAaraghlevvklLLkh 24 L +A+++g+++++ +LL++ FUN_001008-T2 255 LLAVAVKYGSVQCIDWLLEE 274 566899************54 PP == domain 3 score: -3.2 bits; conditional E-value: 6.6 Ank 6 LHlAaraghlevvklLL 22 +H A+++ + ++ LL FUN_001008-T2 291 IHEAIQHEQDGSLRCLL 307 69999777777777777 PP == domain 4 score: 14.7 bits; conditional E-value: 1.4e-05 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G T H+Aar+g++++++ L++h+ dv dk FUN_001008-T2 324 GVTLAHVAAREGQISCLQALVDHNIDVTSEDK 355 77899****************88999988775 PP == domain 5 score: 0.6 bits; conditional E-value: 0.4 Ank 1 dGnTPLHlAaraghlevvklLL 22 dG++P +A ag++++ ++L+ FUN_001008-T2 356 DGRSPADYAYAAGQTSCGRYLV 377 799999999999*****99998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 2.9e-05 0.091 1 28 [. 215 242 .. 215 244 .. 0.89 2 ! 9.4 0.0 0.00084 2.7 2 24 .. 252 274 .. 251 279 .. 0.87 3 ? -3.4 0.0 8 2.6e+04 6 23 .. 291 308 .. 290 312 .. 0.70 4 ! 12.0 0.0 0.00011 0.36 2 29 .. 324 350 .. 323 352 .. 0.93 5 ? -1.5 0.0 2.9 9.4e+03 1 23 [. 356 378 .. 356 383 .. 0.83 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 2.9e-05 Ank_3 1 dgntpLhlAarngrleivklLleklgad 28 +gnt+Lh Aa+ g+l +++L+ +l+ d FUN_001008-T2 215 FGNTALHKAAEAGSLSTLQWLVSRLPND 242 59*************99****9977666 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00084 Ank_3 2 gntpLhlAarngrleivklLlek 24 + ++L +A+++g+++ +++Lle+ FUN_001008-T2 252 NLSLLAVAVKYGSVQCIDWLLEE 274 568999***************94 PP == domain 3 score: -3.4 bits; conditional E-value: 8 Ank_3 6 LhlAarngrleivklLle 23 +h A+ + + +++Ll FUN_001008-T2 291 IHEAIQHEQDGSLRCLLA 308 688888877766777776 PP == domain 4 score: 12.0 bits; conditional E-value: 0.00011 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g t+ h+Aar g++ +++L++ +++d+ FUN_001008-T2 324 GVTLAHVAAREGQISCLQALVD-HNIDV 350 789*******************.99997 PP == domain 5 score: -1.5 bits; conditional E-value: 2.9 Ank_3 1 dgntpLhlAarngrleivklLle 23 dg++p +A g+ ++L+ FUN_001008-T2 356 DGRSPADYAYAAGQTSCGRYLVM 378 69999999999999888888875 PP >> CtIP_N Tumour-suppressor protein CtIP N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.36 1.2e+03 59 91 .. 59 91 .. 48 115 .. 0.72 2 ? 12.6 0.3 4.3e-05 0.14 36 76 .. 388 428 .. 377 444 .. 0.87 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.36 CtIP_N 59 kvLEnrLraglCdrCavtqellkkkqqefessq 91 LE+ L+a + + v++e++ ++ +f++ + FUN_001008-T2 59 LYLEECLKALDGNAHEVQEEEIDLEEYDFDDYN 91 469999999999999999999999999998753 PP == domain 2 score: 12.6 bits; conditional E-value: 4.3e-05 CtIP_N 36 rleelfsknqqlrEqqkvlkenikvLEnrLraglCdrCavt 76 r+ +l+ ++ ++++k l+++++vLEn+ r+gl +r v FUN_001008-T2 388 RIAKLHRELKECKDENKDLRQKLEVLENQTRTGLPNRPEVV 428 889999999*************************9998775 PP >> CCDC92 Coiled-coil domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 1.0 4.2e-05 0.13 24 49 .. 391 416 .. 389 420 .. 0.88 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.2e-05 CCDC92 24 gLHkEIerLqkrnkdLtfklvmkege 49 +LH E+++ + +nkdL +kl++ e + FUN_001008-T2 391 KLHRELKECKDENKDLRQKLEVLENQ 416 8*******************987765 PP >> TPR_NUP160_120_M NUP160/120 middle TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 8.7e-05 0.28 100 169 .. 271 344 .. 246 354 .. 0.86 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 8.7e-05 TPR_NUP160_120_M 100 lfeqvslpelvielAe.tAl...seaekddpnlatLwsiiFkhhLelghyeeAyealianpdssrrkdclrqLv 169 l+e++s+ + + +lA+ +Al ++ +++d +l L i hLel+ ++ + +l++ + ++ + cl+ Lv FUN_001008-T2 271 LLEETSAADEISNLASrSALiheAIQHEQDGSLRCLLAYIRDKHLELDVTDSSGVTLAHVAAREGQISCLQALV 344 8999**********962566443344668999*****************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (605 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1227 (0.0480329); expected 510.9 (0.02) Passed bias filter: 710 (0.0277941); expected 510.9 (0.02) Passed Vit filter: 93 (0.00364063); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5759.52 // Query: FUN_001008-T3 [L=861] Description: FUN_001008 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-22 80.0 3.5 7.5e-09 36.5 0.0 2.7 3 Ank_2 Ankyrin repeats (3 copies) 4.1e-16 59.2 2.9 6.4e-05 23.6 0.1 4.4 4 Ank_4 Ankyrin repeats (many copies) 5.9e-14 52.5 0.1 0.00015 22.5 0.0 3.6 3 Ank_5 Ankyrin repeats (many copies) 2.1e-10 40.8 2.3 0.024 15.5 0.0 4.6 5 Ank Ankyrin repeat 5.1e-10 39.1 0.0 0.14 13.3 0.0 4.4 4 Ank_3 Ankyrin repeat ------ inclusion threshold ------ 0.074 13.4 1.0 0.2 12.0 1.0 1.7 1 CCDC92 Coiled-coil domain of unknown function 0.2 12.1 3.9 0.22 11.9 0.3 2.7 3 CtIP_N Tumour-suppressor protein CtIP N-terminal domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 0.1 1.9e-10 6.9e-07 23 82 .. 193 257 .. 177 266 .. 0.81 2 ! 30.2 0.2 2e-10 7.2e-07 1 82 [. 203 292 .. 203 299 .. 0.81 3 ! 36.5 0.0 2.1e-12 7.5e-09 2 81 .. 275 361 .. 274 367 .. 0.81 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 1.9e-10 Ank_2 23 nlqdkngetaLhlAaknghleivklLle...hgad..vn..dnngrtaLhyAaesghleivklLlek 82 +++d +g+taLh Aa++g+l ++++L++ + d n + ++ + L +A+++g+++++ +Lle+ FUN_001008-T3 193 RITDAFGNTALHKAAEAGSLSTLQWLVSrlpN--DclGNitNGENLSLLAVAVKYGSVQCIDWLLEE 257 567789*********************95553..122334348899999****************65 PP == domain 2 score: 30.2 bits; conditional E-value: 2e-10 Ank_2 1 LmlAakngnlelvklLl....egadanlqdkngetaLhlAaknghleivklLlehgadvn...dnngrtaL.hyAaesghleivklLlek 82 L+ Aa+ g+l+++++L+ +++ n+++ ++ + L +A+k+g+++++ +Lle+ +++ + r+aL h A+++ + ++ Ll + FUN_001008-T3 203 LHKAAEAGSLSTLQWLVsrlpNDCLGNITNGENLSLLAVAVKYGSVQCIDWLLEETSAADeisNLASRSALiHEAIQHEQDGSLRCLLAY 292 89***************7643334446777799********************975334445557799***9******999999999854 PP == domain 3 score: 36.5 bits; conditional E-value: 2.1e-12 Ank_2 2 mlAakngnlelvklLl.....egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 + A+++++ ++ Ll ++ + +++d+ g t h+Aa+ g++ ++++L++h++dv d++gr++ yA g+ + ++L+ FUN_001008-T3 275 HEAIQHEQDGSLRCLLayirdKHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTseDKDGRSPADYAYAAGQTSCGRYLVM 361 7888854444555554433677788888888************************87776899**********************94 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 3.8e-07 0.0014 23 50 .] 192 219 .. 169 219 .. 0.80 2 ! 23.6 0.1 1.8e-08 6.4e-05 1 50 [] 203 255 .. 203 255 .. 0.95 3 ! 19.5 0.1 3.6e-07 0.0013 2 50 .] 275 327 .. 274 327 .. 0.84 4 ! 20.0 0.0 2.5e-07 0.00092 2 49 .. 312 359 .. 311 360 .. 0.90 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 3.8e-07 Ank_4 23 inatdgngetaLhfAasngnlevlklLl 50 + td +g+taLh+Aa g+l+ l++L+ FUN_001008-T3 192 VRITDAFGNTALHKAAEAGSLSTLQWLV 219 556799********************96 PP == domain 2 score: 23.6 bits; conditional E-value: 1.8e-08 Ank_4 1 lhaAaksghlellklLlengad...inatdgngetaLhfAasngnlevlklLl 50 lh+Aa++g l +l++L++ ++ n t+g+ + L A++ g+++++ +Ll FUN_001008-T3 203 LHKAAEAGSLSTLQWLVSRLPNdclGNITNGENLSLLAVAVKYGSVQCIDWLL 255 8****************987777989999***********************8 PP == domain 3 score: 19.5 bits; conditional E-value: 3.6e-07 Ank_4 2 haAak...sghlel.lklLlengadinatdgngetaLhfAasngnlevlklLl 50 h A+ +g l++ l ++ ++ ++++ td +g t h Aa+ g++++l+ L+ FUN_001008-T3 275 HEAIQheqDGSLRClLAYIRDKHLELDVTDSSGVTLAHVAAREGQISCLQALV 327 66666666788888455777******************************995 PP == domain 4 score: 20.0 bits; conditional E-value: 2.5e-07 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 h+Aa +g++ +l+ L+++ +d+ d++g+++ ++A + g++++ ++L FUN_001008-T3 312 HVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYAYAAGQTSCGRYL 359 99****************8886666***************99997777 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 3.6e-07 0.0013 11 56 .] 194 242 .. 191 242 .. 0.92 2 ! 11.9 0.0 8.9e-05 0.32 9 37 .. 228 256 .. 224 268 .. 0.87 3 ! 22.5 0.0 4.1e-08 0.00015 5 56 .] 295 347 .. 293 347 .. 0.95 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 3.6e-07 Ank_5 11 rldgegytpLhvAakygaleivrlLl...angvdlnlkdeegltpldlA 56 ++d +g+t+Lh+Aa++g+l +++L+ n++ n+++ e+l++l +A FUN_001008-T3 194 ITDAFGNTALHKAAEAGSLSTLQWLVsrlPNDCLGNITNGENLSLLAVA 242 67889**********************999************9998766 PP == domain 2 score: 11.9 bits; conditional E-value: 8.9e-05 Ank_5 9 lnrldgegytpLhvAakygaleivrlLla 37 n+++ge L vA+kyg+ +++ +Ll+ FUN_001008-T3 228 GNITNGENLSLLAVAVKYGSVQCIDWLLE 256 4999************************3 PP == domain 3 score: 22.5 bits; conditional E-value: 4.1e-08 Ank_5 5 g.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + ++ l+ +d g+t hvAa+ g +++ L++++ d++ d++g +p d+A FUN_001008-T3 295 DkHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYA 347 44788999********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 6.4e-06 0.024 2 23 .. 199 220 .. 198 230 .. 0.90 2 ! 6.8 0.0 0.0038 14 5 24 .. 238 257 .. 234 266 .. 0.77 3 ? -3.7 0.1 7 2.6e+04 6 22 .. 274 290 .. 273 292 .. 0.74 4 ! 14.1 0.0 1.8e-05 0.066 2 33 .] 307 338 .. 306 338 .. 0.89 5 ? -0.0 0.0 0.55 2e+03 1 22 [. 339 360 .. 339 367 .. 0.86 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6.4e-06 Ank 2 GnTPLHlAaraghlevvklLLk 23 GnT+LH Aa+ag+l+++++L++ FUN_001008-T3 199 GNTALHKAAEAGSLSTLQWLVS 220 9*******************94 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0038 Ank 5 PLHlAaraghlevvklLLkh 24 L +A+++g+++++ +LL++ FUN_001008-T3 238 LLAVAVKYGSVQCIDWLLEE 257 566899************54 PP == domain 3 score: -3.7 bits; conditional E-value: 7 Ank 6 LHlAaraghlevvklLL 22 +H A+++ + ++ LL FUN_001008-T3 274 IHEAIQHEQDGSLRCLL 290 69999777777777777 PP == domain 4 score: 14.1 bits; conditional E-value: 1.8e-05 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G T H+Aar+g++++++ L++h+ dv dk FUN_001008-T3 307 GVTLAHVAAREGQISCLQALVDHNIDVTSEDK 338 77889****************88999988775 PP == domain 5 score: -0.0 bits; conditional E-value: 0.55 Ank 1 dGnTPLHlAaraghlevvklLL 22 dG++P +A ag++++ ++L+ FUN_001008-T3 339 DGRSPADYAYAAGQTSCGRYLV 360 799999999999*****99998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.0 3.8e-05 0.14 1 28 [. 198 225 .. 198 227 .. 0.89 2 ! 8.8 0.0 0.0011 4.1 2 24 .. 235 257 .. 234 262 .. 0.87 3 ! 11.5 0.0 0.00015 0.55 2 29 .. 307 333 .. 306 335 .. 0.93 4 ? -2.1 0.0 4.1 1.5e+04 1 23 [. 339 361 .. 339 365 .. 0.82 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 3.8e-05 Ank_3 1 dgntpLhlAarngrleivklLleklgad 28 +gnt+Lh Aa+ g+l +++L+ +l+ d FUN_001008-T3 198 FGNTALHKAAEAGSLSTLQWLVSRLPND 225 59*************99****9977666 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0011 Ank_3 2 gntpLhlAarngrleivklLlek 24 + ++L +A+++g+++ +++Lle+ FUN_001008-T3 235 NLSLLAVAVKYGSVQCIDWLLEE 257 568999***************94 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00015 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g t+ h+Aar g++ +++L++ +++d+ FUN_001008-T3 307 GVTLAHVAAREGQISCLQALVD-HNIDV 333 789*******************.99997 PP == domain 4 score: -2.1 bits; conditional E-value: 4.1 Ank_3 1 dgntpLhlAarngrleivklLle 23 dg++p +A g+ ++L+ FUN_001008-T3 339 DGRSPADYAYAAGQTSCGRYLVM 361 69999999999998888888875 PP >> CCDC92 Coiled-coil domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 1.0 5.5e-05 0.2 24 49 .. 374 399 .. 372 403 .. 0.88 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.5e-05 CCDC92 24 gLHkEIerLqkrnkdLtfklvmkege 49 +LH E+++ + +nkdL +kl++ e + FUN_001008-T3 374 KLHRELKECKDENKDLRQKLEVLENQ 399 8*******************987765 PP >> CtIP_N Tumour-suppressor protein CtIP N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 0.52 1.9e+03 59 91 .. 42 74 .. 31 96 .. 0.72 2 ? 11.9 0.3 6.1e-05 0.22 36 76 .. 371 411 .. 361 427 .. 0.87 3 ? -2.9 0.1 2.4 8.7e+03 64 78 .. 777 791 .. 776 793 .. 0.82 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.52 CtIP_N 59 kvLEnrLraglCdrCavtqellkkkqqefessq 91 LE+ L+a + + v++e++ ++ +f++ + FUN_001008-T3 42 LYLEECLKALDGNAHEVQEEEIDLEEYDFDDYN 74 469999999999999999999999999888753 PP == domain 2 score: 11.9 bits; conditional E-value: 6.1e-05 CtIP_N 36 rleelfsknqqlrEqqkvlkenikvLEnrLraglCdrCavt 76 r+ +l+ ++ ++++k l+++++vLEn+ r+gl +r v FUN_001008-T3 371 RIAKLHRELKECKDENKDLRQKLEVLENQTRTGLPNRPEVV 411 889999999*************************9998775 PP == domain 3 score: -2.9 bits; conditional E-value: 2.4 CtIP_N 64 rLraglCdrCavtqe 78 rL ++Cdr ++ ++ FUN_001008-T3 777 RLTGSECDRTMLRDN 791 78899****998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (861 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 994 (0.0389117); expected 510.9 (0.02) Passed bias filter: 552 (0.0216089); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.40u 0.37s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 8403.57 // Query: FUN_001008-T4 [L=878] Description: FUN_001008 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-22 79.9 3.4 7.7e-09 36.5 0.0 2.7 3 Ank_2 Ankyrin repeats (3 copies) 4.9e-16 58.9 2.9 6.6e-05 23.6 0.1 4.5 4 Ank_4 Ankyrin repeats (many copies) 6.2e-14 52.4 0.1 0.00015 22.5 0.0 3.6 3 Ank_5 Ankyrin repeats (many copies) 2.2e-10 40.7 2.3 0.024 15.5 0.0 4.6 5 Ank Ankyrin repeat 5.5e-10 39.0 0.0 0.14 13.3 0.0 4.4 4 Ank_3 Ankyrin repeat ------ inclusion threshold ------ 0.076 13.3 1.0 0.21 12.0 1.0 1.7 1 CCDC92 Coiled-coil domain of unknown function 0.2 12.1 3.9 0.23 11.9 0.3 2.7 3 CtIP_N Tumour-suppressor protein CtIP N-terminal domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 0.1 1.9e-10 7e-07 23 82 .. 210 274 .. 194 283 .. 0.81 2 ! 30.1 0.2 2e-10 7.4e-07 1 82 [. 220 309 .. 220 316 .. 0.81 3 ! 36.5 0.0 2.1e-12 7.7e-09 2 81 .. 292 378 .. 291 384 .. 0.81 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 1.9e-10 Ank_2 23 nlqdkngetaLhlAaknghleivklLle...hgad..vn..dnngrtaLhyAaesghleivklLlek 82 +++d +g+taLh Aa++g+l ++++L++ + d n + ++ + L +A+++g+++++ +Lle+ FUN_001008-T4 210 RITDAFGNTALHKAAEAGSLSTLQWLVSrlpN--DclGNitNGENLSLLAVAVKYGSVQCIDWLLEE 274 567789*********************95553..122334348899999****************65 PP == domain 2 score: 30.1 bits; conditional E-value: 2e-10 Ank_2 1 LmlAakngnlelvklLl....egadanlqdkngetaLhlAaknghleivklLlehgadvn...dnngrtaL.hyAaesghleivklLlek 82 L+ Aa+ g+l+++++L+ +++ n+++ ++ + L +A+k+g+++++ +Lle+ +++ + r+aL h A+++ + ++ Ll + FUN_001008-T4 220 LHKAAEAGSLSTLQWLVsrlpNDCLGNITNGENLSLLAVAVKYGSVQCIDWLLEETSAADeisNLASRSALiHEAIQHEQDGSLRCLLAY 309 89***************7643334446777799********************975334445557799***9******999999999854 PP == domain 3 score: 36.5 bits; conditional E-value: 2.1e-12 Ank_2 2 mlAakngnlelvklLl.....egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 + A+++++ ++ Ll ++ + +++d+ g t h+Aa+ g++ ++++L++h++dv d++gr++ yA g+ + ++L+ FUN_001008-T4 292 HEAIQHEQDGSLRCLLayirdKHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTseDKDGRSPADYAYAAGQTSCGRYLVM 378 7888854444555554433677788888888************************87776899**********************94 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 3.9e-07 0.0014 23 50 .] 209 236 .. 186 236 .. 0.80 2 ! 23.6 0.1 1.8e-08 6.6e-05 1 50 [] 220 272 .. 220 272 .. 0.95 3 ! 19.5 0.1 3.7e-07 0.0013 2 50 .] 292 344 .. 291 344 .. 0.84 4 ! 19.9 0.0 2.6e-07 0.00095 2 49 .. 329 376 .. 328 377 .. 0.90 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 3.9e-07 Ank_4 23 inatdgngetaLhfAasngnlevlklLl 50 + td +g+taLh+Aa g+l+ l++L+ FUN_001008-T4 209 VRITDAFGNTALHKAAEAGSLSTLQWLV 236 556799********************96 PP == domain 2 score: 23.6 bits; conditional E-value: 1.8e-08 Ank_4 1 lhaAaksghlellklLlengad...inatdgngetaLhfAasngnlevlklLl 50 lh+Aa++g l +l++L++ ++ n t+g+ + L A++ g+++++ +Ll FUN_001008-T4 220 LHKAAEAGSLSTLQWLVSRLPNdclGNITNGENLSLLAVAVKYGSVQCIDWLL 272 8****************987777989999***********************8 PP == domain 3 score: 19.5 bits; conditional E-value: 3.7e-07 Ank_4 2 haAak...sghlel.lklLlengadinatdgngetaLhfAasngnlevlklLl 50 h A+ +g l++ l ++ ++ ++++ td +g t h Aa+ g++++l+ L+ FUN_001008-T4 292 HEAIQheqDGSLRClLAYIRDKHLELDVTDSSGVTLAHVAAREGQISCLQALV 344 66666666788888455777******************************995 PP == domain 4 score: 19.9 bits; conditional E-value: 2.6e-07 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 h+Aa +g++ +l+ L+++ +d+ d++g+++ ++A + g++++ ++L FUN_001008-T4 329 HVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYAYAAGQTSCGRYL 376 99****************8886666***************99997777 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 3.7e-07 0.0013 11 56 .] 211 259 .. 208 259 .. 0.92 2 ! 11.9 0.0 9.1e-05 0.33 9 37 .. 245 273 .. 241 285 .. 0.87 3 ! 22.5 0.0 4.2e-08 0.00015 5 56 .] 312 364 .. 310 364 .. 0.95 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 3.7e-07 Ank_5 11 rldgegytpLhvAakygaleivrlLl...angvdlnlkdeegltpldlA 56 ++d +g+t+Lh+Aa++g+l +++L+ n++ n+++ e+l++l +A FUN_001008-T4 211 ITDAFGNTALHKAAEAGSLSTLQWLVsrlPNDCLGNITNGENLSLLAVA 259 67889**********************999************9998766 PP == domain 2 score: 11.9 bits; conditional E-value: 9.1e-05 Ank_5 9 lnrldgegytpLhvAakygaleivrlLla 37 n+++ge L vA+kyg+ +++ +Ll+ FUN_001008-T4 245 GNITNGENLSLLAVAVKYGSVQCIDWLLE 273 4999************************3 PP == domain 3 score: 22.5 bits; conditional E-value: 4.2e-08 Ank_5 5 g.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + ++ l+ +d g+t hvAa+ g +++ L++++ d++ d++g +p d+A FUN_001008-T4 312 DkHLELDVTDSSGVTLAHVAAREGQISCLQALVDHNIDVTSEDKDGRSPADYA 364 44788999********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 6.6e-06 0.024 2 23 .. 216 237 .. 215 247 .. 0.90 2 ! 6.8 0.0 0.0039 14 5 24 .. 255 274 .. 251 283 .. 0.77 3 ? -3.8 0.1 7 2.6e+04 6 22 .. 291 307 .. 290 309 .. 0.74 4 ! 14.0 0.0 1.9e-05 0.068 2 33 .] 324 355 .. 323 355 .. 0.89 5 ? -0.0 0.0 0.56 2.1e+03 1 22 [. 356 377 .. 356 384 .. 0.86 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6.6e-06 Ank 2 GnTPLHlAaraghlevvklLLk 23 GnT+LH Aa+ag+l+++++L++ FUN_001008-T4 216 GNTALHKAAEAGSLSTLQWLVS 237 9*******************94 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0039 Ank 5 PLHlAaraghlevvklLLkh 24 L +A+++g+++++ +LL++ FUN_001008-T4 255 LLAVAVKYGSVQCIDWLLEE 274 566899************54 PP == domain 3 score: -3.8 bits; conditional E-value: 7 Ank 6 LHlAaraghlevvklLL 22 +H A+++ + ++ LL FUN_001008-T4 291 IHEAIQHEQDGSLRCLL 307 69999777777777777 PP == domain 4 score: 14.0 bits; conditional E-value: 1.9e-05 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G T H+Aar+g++++++ L++h+ dv dk FUN_001008-T4 324 GVTLAHVAAREGQISCLQALVDHNIDVTSEDK 355 77889****************88999988775 PP == domain 5 score: -0.0 bits; conditional E-value: 0.56 Ank 1 dGnTPLHlAaraghlevvklLL 22 dG++P +A ag++++ ++L+ FUN_001008-T4 356 DGRSPADYAYAAGQTSCGRYLV 377 799999999999*****99998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.0 3.9e-05 0.14 1 28 [. 215 242 .. 215 244 .. 0.89 2 ! 8.8 0.0 0.0011 4.2 2 24 .. 252 274 .. 251 279 .. 0.87 3 ! 11.4 0.0 0.00015 0.56 2 29 .. 324 350 .. 323 352 .. 0.93 4 ? -2.1 0.0 4.2 1.5e+04 1 23 [. 356 378 .. 356 382 .. 0.82 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 3.9e-05 Ank_3 1 dgntpLhlAarngrleivklLleklgad 28 +gnt+Lh Aa+ g+l +++L+ +l+ d FUN_001008-T4 215 FGNTALHKAAEAGSLSTLQWLVSRLPND 242 59*************99****9977666 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0011 Ank_3 2 gntpLhlAarngrleivklLlek 24 + ++L +A+++g+++ +++Lle+ FUN_001008-T4 252 NLSLLAVAVKYGSVQCIDWLLEE 274 568999***************94 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00015 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g t+ h+Aar g++ +++L++ +++d+ FUN_001008-T4 324 GVTLAHVAAREGQISCLQALVD-HNIDV 350 789*******************.99997 PP == domain 4 score: -2.1 bits; conditional E-value: 4.2 Ank_3 1 dgntpLhlAarngrleivklLle 23 dg++p +A g+ ++L+ FUN_001008-T4 356 DGRSPADYAYAAGQTSCGRYLVM 378 69999999999998888888875 PP >> CCDC92 Coiled-coil domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 1.0 5.6e-05 0.21 24 49 .. 391 416 .. 389 420 .. 0.88 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.6e-05 CCDC92 24 gLHkEIerLqkrnkdLtfklvmkege 49 +LH E+++ + +nkdL +kl++ e + FUN_001008-T4 391 KLHRELKECKDENKDLRQKLEVLENQ 416 8*******************987765 PP >> CtIP_N Tumour-suppressor protein CtIP N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.53 1.9e+03 60 91 .. 60 91 .. 48 113 .. 0.72 2 ? 11.9 0.3 6.3e-05 0.23 36 76 .. 388 428 .. 378 444 .. 0.87 3 ? -2.9 0.1 2.4 8.9e+03 64 78 .. 794 808 .. 793 810 .. 0.82 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.53 CtIP_N 60 vLEnrLraglCdrCavtqellkkkqqefessq 91 LE+ L+a + + v++e++ ++ +f++ + FUN_001008-T4 60 YLEECLKALDGNAHEVQEEEIDLEEYDFDDYN 91 69999999999999999999999999888753 PP == domain 2 score: 11.9 bits; conditional E-value: 6.3e-05 CtIP_N 36 rleelfsknqqlrEqqkvlkenikvLEnrLraglCdrCavt 76 r+ +l+ ++ ++++k l+++++vLEn+ r+gl +r v FUN_001008-T4 388 RIAKLHRELKECKDENKDLRQKLEVLENQTRTGLPNRPEVV 428 889999999*************************9998775 PP == domain 3 score: -2.9 bits; conditional E-value: 2.4 CtIP_N 64 rLraglCdrCavtqe 78 rL ++Cdr ++ ++ FUN_001008-T4 794 RLTGSECDRTMLRDN 808 78899****998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (878 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1025 (0.0401253); expected 510.9 (0.02) Passed bias filter: 557 (0.0218047); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 8397.40 // Query: FUN_001009-T1 [L=775] Description: FUN_001009 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-93 312.3 0.7 1.3e-92 311.7 0.7 1.3 1 Peptidase_M13_N Peptidase family M13 2e-63 214.2 0.0 3.3e-63 213.5 0.0 1.3 1 Peptidase_M13 Peptidase family M13 Domain annotation for each model (and alignments): >> Peptidase_M13_N Peptidase family M13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 311.7 0.7 1e-96 1.3e-92 1 382 [] 116 506 .. 116 506 .. 0.91 Alignments for each domain: == domain 1 score: 311.7 bits; conditional E-value: 1e-96 Peptidase_M13_N 1 PcdDFyeyaCGgWlknhpipadksswgtfeelreknekqlreileeaaasksdasaeekakdlYkscmdteaieklglkplkellkeigga... 91 Pc++F++yaCG W+k++pip++k+ + f+ ++kn +++re+lee+ a++sd+sa+ kak ++ksc ++ ++ek ++ lk+l++++g + FUN_001009-T1 116 PCKNFFQYACGSWIKDNPIPPSKTVLDEFTAAEDKNYQTMREMLEESIATSSDRSAVGKAKLYFKSCIQEGQVEKTAMQLLKPLIAKYGHWalg 209 9*********************************************999999****99*******************************98898 PP Peptidase_M13_N 92 sa.wks.kfdlaellaklrr.ygvdslfglgvdpddknssrnilyldqpglglpdrdyylkerdeksaeileaykeylakllkllgadeeeaaa 182 s+ w+s ++++++++ ++++ ++++++l++d +++nss+ +l l +p+l+l rd yl ++++++ ay+e+++k+ kllg ++ ++ FUN_001009-T1 210 SQeWNStEWNWLKVMTYMDSeIMAFPFLSLYIDFNPRNSSQFMLALHPPELSLI-RDQYLA----EENKTRLAYLEFMTKVGKLLGG-GNTTRK 297 4456777************96777788**************************9.777763....35678***************98.566999 PP Peptidase_M13_N 183 eaeevlafetklakisldreerrdpektynpmtlaelqklapgid..wkaylka.....llpke...eseevivsepeylkklskllaetplrt 266 ++e+v++fe klaki +++ e r ++ + m+l+ l+ +apgi w +yl+ s++v+v + eylk+ls +++ t +rt FUN_001009-T1 298 QMEDVMKFEGKLAKIIPPKSEIRA--NYHQAMNLTTLEHKAPGIGftWLEYLNGvmkyfN---IslnGSDRVLVPSVEYLKNLSIVINGTEKRT 386 ****************99777733..333459999999888966444*****99665442...14558*******************77***** PP Peptidase_M13_N 267 lknyliwrlvsslapylskefrdanfefyktlsgtkqr.prwkrcvslvnsl...lgealgrlyvkkyfpeeakakveelvenikeafkerlee 356 l ny+iw +v+s++pyls++fr+a+ +f+k+ +g+kq+ prw cv+ +ns+ l +a+g++ ++ +f+ + +ee+++ i af++ + FUN_001009-T1 387 LSNYMIWTFVRSVIPYLSRNFREAYLDFQKATQGKKQAkPRWLSCVEDMNSYthgLTFAMGYMWIQSAFDVKMIPLIEEMMRGISVAFRDETPN 480 ************************************888***********744459************************************** PP Peptidase_M13_N 357 ldWmdeetkkkAleKldaikvkigyp 382 dW de+t+kk leK +a+k k+g+p FUN_001009-T1 481 YDWVDEQTRKKILEKEKAMKFKVGFP 506 *************************9 PP >> Peptidase_M13 Peptidase family M13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 213.5 0.0 2.6e-67 3.3e-63 1 205 [] 564 774 .. 564 774 .. 0.94 Alignments for each domain: == domain 1 score: 213.5 bits; conditional E-value: 2.6e-67 Peptidase_M13 1 NAyYqpeeneivfpaailqppfF.dleypkavNyggiGaviaHEitHgfddqgvqfdkegnlaswltde.daeefkekakclieqfsevtepdktk 94 NA+Y p++nei ++a+ilqppf+ ++p+avNyg+iG++++HE++Hgfd +g+ f+k+g+l++ l+++ +++f+++a+c+ eq+s + + + FUN_001009-T1 564 NAFYLPSRNEINILAGILQPPFYyGRTAPRAVNYGAIGMILGHELSHGFDANGRVFNKDGELIDNLWTNyTTQGFEKRAQCMEEQYSRYSVNGGEL 659 9********************8626899**********************************987766626789***************9886644 PP Peptidase_M13 95 ...avngsltlgEniADlggleiAlraykk..lksakeevlpelenltkdqlfFisyAqiwcekqsdeeslrqllvdvHspaelRvngvlsnlpaF 185 +++g+ltl+EniAD+gg++iA+ yk k+ ke lp+l+ t++qlfF s+Aq+wc++ +++++++ + +d H a++Rv g+lsn+++F FUN_001009-T1 660 gqiEIDGKLTLSENIADNGGIRIAYWGYKDwvEKNGKEMLLPGLN-KTNEQLFFLSFAQMWCSSYTPAAAYMLAKTDSHTLAKYRVIGTLSNIKEF 754 679***************************877788888889998.8899********************************************** PP Peptidase_M13 186 aeaFnckegdkmnpekekrv 205 +eaF+ck g++mnpek+++v FUN_001009-T1 755 SEAFKCKVGSRMNPEKKCHV 774 ******************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (775 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1054 (0.0412605); expected 510.9 (0.02) Passed bias filter: 895 (0.0350362); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.36s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 7646.78 // Query: FUN_001010-T1 [L=395] Description: FUN_001010 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-11 44.4 0.0 5.2e-11 43.5 0.0 1.4 1 DHHA2 DHHA2 domain 5.2e-06 27.2 0.0 1.1e-05 26.2 0.0 1.5 1 DHH DHH family, N-terminal domain Domain annotation for each model (and alignments): >> DHHA2 DHHA2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.5 0.0 4.1e-15 5.2e-11 5 125 .. 247 389 .. 246 390 .. 0.78 Alignments for each domain: == domain 1 score: 43.5 bits; conditional E-value: 4.1e-15 DHHA2 5 kaksdlsglsaeellrkDyKeft...lgglkvgisqvevvleewleerkdellaalekfa.erkgldllllmtt.......gdilrslllvalslg 89 + k+d+ gls+++llrkDyK +++ vgis + ++++r d +++++ ++ ld+l++m++ + +r+++++ + FUN_001010-T1 247 TSKFDVAGLSTRDLLRKDYKALPkhnNETPAVGISALSGLSMGEFFSR-DRVQDDILVYCqTAALLDVLVVMFVhfpdgykEPPQRQIAVCG-P-C 339 579*******************999888899******87777777774.6799999999987778***********9877666666999988.4.5 PP DHHA2 90 eelvekafekakedesldLe...........r.....gvvsrkKqvvPllke 125 e+ + + + + s++L+ + ++ +++K v Pl+ + FUN_001010-T1 340 ED-LRTNIARYLQ-ASVELQlieysecpqdcFlydqgNITATRKVVFPLVND 389 55.4444444444.33555555888988776155679************976 PP >> DHH DHH family, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 8.4e-10 1.1e-05 3 102 .. 23 162 .. 22 181 .. 0.64 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 8.4e-10 xxxxxxxxxxxxxxxxxxxxxxx..xxx..............xxxxxxxxxxxx.........................................x RF DHH 3 livghynpDvDgigSalalyell..kel..............egpeveylipdr.........................................d 41 +++g++ D+D+++S+l+++ + k l + FUN_001010-T1 23 VVLGNEACDLDSMVSSLVYA-FSffKTLssfpgssvavipvfN----------MpqqdfslrteavflfgrchidpalftfnddielqtlldakrL 107 699**************954.3335553433333222222222..........1334666666789999999999999999999999999999877 PP xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF DHH 42 llitvDhgess..veeieeakelgidviviDHHlpeeflpeadailnpkeppasstvevvfkl 102 +l++vDh++ s + ++ ++ +i +DHH+ p ++ + ++s++++v++ FUN_001010-T1 108 KLVLVDHNILSqaQRHMDV----AVMEI-LDHHKDM-W-PLNL-KVKKTIELVGSCSTLVAEK 162 9*********963333333....58888.9***543.2.2222.2333344455777777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (395 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 746 (0.0292034); expected 510.9 (0.02) Passed bias filter: 608 (0.0238011); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3811.03 // Query: FUN_001011-T1 [L=231] Description: FUN_001011 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-43 148.3 5.5 5e-43 148.0 5.5 1.0 1 L_HMGIC_fpl Lipoma HMGIC fusion partner-like protein 0.00024 21.4 9.7 0.00086 19.6 9.4 1.9 1 Claudin_2 PMP-22/EMP/MP20/Claudin tight junction ------ inclusion threshold ------ 0.061 13.8 7.7 0.11 12.9 7.7 1.4 1 Claudin_3 Tight junction protein, Claudin-like 0.97 9.8 11.0 4.5 7.7 11.0 2.1 1 PMP22_Claudin PMP-22/EMP/MP20/Claudin family Domain annotation for each model (and alignments): >> L_HMGIC_fpl Lipoma HMGIC fusion partner-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 148.0 5.5 7.8e-47 5e-43 3 181 .] 13 207 .. 11 207 .. 0.91 Alignments for each domain: == domain 1 score: 148.0 bits; conditional E-value: 7.8e-47 L_HMGIC_fpl 3 vlWallslvvavlevvafvspeWlvgsqe............sekagslglyerCk....vesqevelecgrsaldflaipssafkaaavfvalgil 82 +lW++ls+v +++ ++ + p+Wl+gs + +++s+g+y+rC + el+c ++ +df+ ips a++a+ +f+ g++ FUN_001011-T1 13 LLWMILSVVSTLAVITGIMRPYWLFGSPTlfgnsssnanseLFYRPSIGIYSRCRkiqrSIGGNPELNCYTYVQDFMDIPSAAWRACLFFLCFGTF 108 79************************9989999999998877899**********754433346789***************************** PP L_HMGIC_fpl 83 lllvvvllsllvlckqsilkksvfkicallqlvaglllvlgcllyPlgWeseevrklCG....eeaekfelglCsirwayylaiigvldalvlafl 174 ll++ v++sl+ +c+qsi kks+f + +++q va+l+lv+g++lyP+gW +++v +lC ++ ++f + +Cs++wa+y+a+ ++++ +fl FUN_001011-T1 109 LLGIAVFMSLVGFCFQSIGKKSIFSVGGVIQSVAALFLVIGLVLYPAGWSNKDVDDLCTikplQKPGAFVINDCSLGWAFYVAL----GGTLASFL 200 **********************************************************8544467899***************9....77888899 PP L_HMGIC_fpl 175 aavlaar 181 ++vl+a+ FUN_001011-T1 201 CSVLSAQ 207 9988875 PP >> Claudin_2 PMP-22/EMP/MP20/Claudin tight junction # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 9.4 1.3e-07 0.00086 86 189 .. 94 204 .. 17 205 .. 0.72 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 1.3e-07 Claudin_2 86 gltrfvqvllilslvlivlgvvlillallkqsv...llllaagilfllagvlgllavvvf.iesvklvfeesvqqwmpehqnnv....risfgWSf 173 + r++ ++l ++ +l+ ++v++ l+++ +qs ++ ++g+++ +a++++++++v++ + ++ ++ ++ +++p ++ s+gW+f FUN_001011-T1 94 AAWRACLFFLCFGTFLLGIAVFMSLVGFCFQSIgkkSIFSVGGVIQSVAALFLVIGLVLYpAGWS-NKDVDDLCTIKPLQKPGAfvinDCSLGWAF 188 455778888888888899999999999999999999************************44566.556788888888775433334689****** PP Claudin_2 174 alAvvgvvllllAglL 189 +A g+ +++l ++L FUN_001011-T1 189 YVALGGTLASFLCSVL 204 ************9987 PP >> Claudin_3 Tight junction protein, Claudin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 7.7 1.8e-05 0.11 10 155 .. 17 207 .. 5 215 .. 0.84 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 1.8e-05 Claudin_3 10 vlvlisfilnivgvftpaWiteksg..........................kkeksiGivP....fss..teagwlaaaswlmyisfalflvvili 73 +l ++s ++ i g++ p+W+ + + k+++siG +P + + +++ + a w ++ f++f + +l FUN_001011-T1 17 ILSVVSTLAVITGIMRPYWLFGSPTlfgnsssnanselfyrpsigiysrcrKIQRSIGGNPelncY-TyvQDFMDIPSAAWRACLFFLCFGTFLLG 111 457888999999999999999999999999999999999999999999999999999988853322.2246666777788999************* PP Claudin_3 74 yivavrkvkkngysksirklflliallslliviltvvaviliavnlssfndsyndss................qLGYsawlavasailslinvaLs 153 ++v+ + v + s ++++f + ++ ++++++ v+ ++l+ + +s+ +d +LG+ +++a++ s+ +Ls FUN_001011-T1 112 IAVFMSLVGFCFQSIGKKSIFSVGGVIQSVAALFLVIGLVLYPAGWSNKDV--DDLCtikplqkpgafvindcSLGWAFYVALGGTLASFLCSVLS 205 **********************************************95543..33223568999999**************999998888888888 PP Claudin_3 154 ih 155 FUN_001011-T1 206 AQ 207 65 PP >> PMP22_Claudin PMP-22/EMP/MP20/Claudin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 11.0 0.0007 4.5 63 157 .. 93 201 .. 8 205 .. 0.68 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0007 PMP22_Claudin 63 edalqavqalmilsiilgiislivfvlqlktlkkgerfkl...aGiiflvsgLcvlvaasiYtsriaeelskslk............kskysfGys 143 + a +a+ ++ ++ l i++++ +++ ++++ ++ + +G+i+ v++L+ ++++ +Y +++ + l ++ s G++ FUN_001011-T1 93 SAAWRACLFFLCFGTFLLGIAVFMSLVG-FCFQSIGKKSIfsvGGVIQSVAALFLVIGLVLYPAGWSNKDVDDLCtikplqkpgafvINDCSLGWA 187 4555666666666666666666666665.55555444333444*******************8766665555443344555666666788889999 PP PMP22_Claudin 144 filgwvafllalls 157 f+++ + l ++l FUN_001011-T1 188 FYVALGGTLASFLC 201 99887777666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (231 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 875 (0.0342533); expected 510.9 (0.02) Passed bias filter: 459 (0.0179683); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2264.66 // Query: FUN_001012-T1 [L=1148] Description: FUN_001012 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-81 272.6 5.7 6.8e-81 272.1 5.7 1.2 1 Glyco_hydro_38N Glycosyl hydrolases family 38 N-terminal dom 1.9e-33 116.9 0.2 6.4e-33 115.2 0.0 2.0 2 Glyco_hydro_38C Glycosyl hydrolases family 38 C-terminal dom 4.9e-22 78.3 0.1 1.3e-21 76.9 0.1 1.8 1 Alpha-mann_mid Alpha mannosidase middle domain 1e-09 38.9 0.0 3.1e-09 37.4 0.0 1.9 1 Laman-like_dom Lysosomal alpha-mannosidase-like, central do Domain annotation for each model (and alignments): >> Glyco_hydro_38N Glycosyl hydrolases family 38 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 272.1 5.7 1.1e-84 6.8e-81 1 269 [. 165 496 .. 165 497 .. 0.96 Alignments for each domain: == domain 1 score: 272.1 bits; conditional E-value: 1.1e-84 Glyco_hydro_38N 1 kvhlvgHsHiDvaWlktvdet.rrkvqrtlssvlellerdpefrFiaseaqlfawlkeeqpelfkri.kklvaegrlevvgGgwvenDealpsg 92 +v++v+HsH+D++W+kt+d++ +++++++l++v+++l +d++++Fi++e+++f+ +++e+ e++k+ + + +g+le+v+Ggwv+nDea++++ FUN_001012-T1 165 NVFVVPHSHNDPGWIKTLDQYyTQQTRHILDNVVDALAEDKRRKFIWAEISYFSMWWSEADENRKKHaLDQLSSGQLEIVTGGWVMNDEANTHY 258 79*******************9*****************************************99999************************** PP Glyco_hydro_38N 93 eslirqllyGqrflkeefg..vkpkvaWlpDpFGysatlPqilkkaGidsfltqrlsyndknkf..ephlefiWrgsdg....seilthmlpad 178 ++++q+++G++++ + +g +kp +W++DpFG++ t++++lk++G++s+l+qr++y+ k+++ +++lef+Wr+ ++ +++++hm+p++ FUN_001012-T1 259 YAMLDQMIEGHQWMSKFLGsaIKPMSGWAIDPFGHTPTMAYLLKRMGFNSMLIQRTHYQVKKHLakDKNLEFMWRQNWDhgssTDMFCHMMPFY 352 *******************999************************************************************************ PP Glyco_hydro_38N 179 sy.........ptygaef..........................keraeellaqakkladktrtnevlllfGdg.........dggggpteell 228 sy p+++++f ++r ++ll+q+kk+a+++rtn + ++Gd+ + +++++++++ FUN_001012-T1 353 SYdvphtcgpePKICCQFdfrrlpgggvtcpwriapqpidvnnvAQRSKMLLDQYKKKAQLYRTNVLFAPLGDDfryettfdtHAQFTNYQRIM 446 99*********99********************************************************************************* PP Glyco_hydro_38N 229 ekinrlqekeslpkvqygtpseyfdalek............lptkdsddfpty 269 ++in e+++kvq+gt+s+yf+al k +p+ s+df ty FUN_001012-T1 447 DYIN--SHPEMKAKVQFGTLSDYFNALFKatgtepggqpknFPAL-SGDFYTY 496 ****..445689***************998888877777777777.7777777 PP >> Glyco_hydro_38C Glycosyl hydrolases family 38 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 1.5 9.9e+03 37 66 .. 492 523 .. 485 536 .. 0.75 2 ! 115.2 0.0 1e-36 6.4e-33 1 206 [] 764 970 .. 764 970 .. 0.94 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 1.5 Glyco_hydro_38C 37 qfqlyedkpg..ssdawdfrpdyeekplevke 66 f y d+ + +s+ + rp+y++ e+++ FUN_001012-T1 492 DFYTYADREDhyWSGYYTSRPFYKNLDRELES 523 57778888888777888888999998877776 PP == domain 2 score: 115.2 bits; conditional E-value: 1e-36 Glyco_hydro_38C 1 leNgllkveidnetGtlksiydkeasrevlaekvgnqfqlyedkpg..ssdawdfrpdyeekplevkeksvevveegplvaevrvklkieesei 92 leN+ +k+e++ ++G+lk+i++k+++ + f y +k + +s+a++f pd + ++ e++ + v +g+l +evrv l + FUN_001012-T1 764 LENDEMKLEFSGASGLLKTITHKKDGTVTE---AAIDFATYGTKSSgdRSGAYLFLPDGPAVTHSKGEQPAIYVIRGKLMQEVRVALPN----V 850 79********************99998876...5899****9998888***************************************99....8 PP Glyco_hydro_38C 93 sqeirly....kgskrlefeteVdwg...erevllkvafpvdi.qaefatdengfgvikRptdkntswekakfevpiqsfvdlsdssygvsvln 178 +++rly ++ + ++++++Vd++ ++e+++++++ v++ + ef+td ngf+++kR+t ++ + +++ + p +s+++l+d+s+++++l+ FUN_001012-T1 851 VHVVRLYsvpgPERRMVDIQNKVDIKnlvNKELVMRIKSSVKNsNREFYTDLNGFQMQKRKTLDKIPIQANFY--PLPSMAFLQDKSTRLTLLS 942 *****************************************986889******************55555555..******************* PP Glyco_hydro_38C 179 dskyGvssekdgqleLsLlRrplypdpr 206 + Gv+s ++g+ ++ L+Rr++++d+r FUN_001012-T1 943 SQPNGVASLHQGEFQVVLDRRLYQDDNR 970 ********66****************86 PP >> Alpha-mann_mid Alpha mannosidase middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.9 0.1 2.1e-25 1.3e-21 1 96 [] 502 606 .. 502 606 .. 0.88 Alignments for each domain: == domain 1 score: 76.9 bits; conditional E-value: 2.1e-25 Alpha-mann_mid 1 elhrgtyTsraklKrlnrkleslLreaellss........aa.vskgyeypkeeleelwkalllnQfHDilpGssikeVyedaeeeleealkele 86 ++++g+yTsr+++K l+r+les+ r+ae+++s + +s +e+ + l++++++l+l+Q+HD ++G++++ V+ d+ +++ ++l+ ++ FUN_001012-T1 502 HYWSGYYTSRPFYKNLDRELESKHRAAEIIFSlaeshvrhRGsSSFPVEKLYGLLTKARQNLALFQHHDGITGTAKDFVVVDYGQRMLQSLNDVQ 596 69******************************877765441133445566667789*************************************** PP Alpha-mann_mid 87 klleealrkL 96 ++++e+++ L FUN_001012-T1 597 SVIQESAQLL 606 ******9976 PP >> Laman-like_dom Lysosomal alpha-mannosidase-like, central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.4 0.0 4.9e-13 3.1e-09 6 46 .] 688 721 .. 684 721 .. 0.91 Alignments for each domain: == domain 1 score: 37.4 bits; conditional E-value: 4.9e-13 Laman-like_dom 6 vpvpswkrvlvktiepqssstkyeLvFkAsVPPLGfstYsV 46 v v+ w++ + ++s++kye++F A+VP+LG++tY+V FUN_001012-T1 688 VNVW-WDH------RNRISTAKYEVLFVAKVPALGLTTYFV 721 5799.999......889***********************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1148 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 799 (0.0312781); expected 510.9 (0.02) Passed bias filter: 687 (0.0268937); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.44u 0.41s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 10896.26 // Query: FUN_001012-T2 [L=899] Description: FUN_001012 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-48 166.5 1.9 1.5e-48 166.0 1.9 1.2 1 Glyco_hydro_38N Glycosyl hydrolases family 38 N-terminal dom 1.9e-33 117.0 1.0 4.3e-33 115.8 0.0 2.1 3 Glyco_hydro_38C Glycosyl hydrolases family 38 C-terminal dom 4e-22 78.6 0.1 9.6e-22 77.4 0.1 1.7 1 Alpha-mann_mid Alpha mannosidase middle domain 8.7e-10 39.2 0.0 2.4e-09 37.8 0.0 1.8 1 Laman-like_dom Lysosomal alpha-mannosidase-like, central do Domain annotation for each model (and alignments): >> Glyco_hydro_38N Glycosyl hydrolases family 38 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 166.0 1.9 2.4e-52 1.5e-48 84 269 .. 1 247 [. 1 248 [. 0.95 Alignments for each domain: == domain 1 score: 166.0 bits; conditional E-value: 2.4e-52 Glyco_hydro_38N 84 enDealpsgeslirqllyGqrflkeefg..vkpkvaWlpDpFGysatlPqilkkaGidsfltqrlsyndknkf..ephlefiWrgsdg....se 169 +nDea++++ ++++q+++G++++ + +g +kp +W++DpFG++ t++++lk++G++s+l+qr++y+ k+++ +++lef+Wr+ ++ ++ FUN_001012-T2 1 MNDEANTHYYAMLDQMIEGHQWMSKFLGsaIKPMSGWAIDPFGHTPTMAYLLKRMGFNSMLIQRTHYQVKKHLakDKNLEFMWRQNWDhgssTD 94 89**************************999*************************************************************** PP Glyco_hydro_38N 170 ilthmlpadsy.........ptygaef..........................keraeellaqakkladktrtnevlllfGdg.........dg 219 +++hm+p++sy p+++++f ++r ++ll+q+kk+a+++rtn + ++Gd+ + FUN_001012-T2 95 MFCHMMPFYSYdvphtcgpePKICCQFdfrrlpgggvtcpwriapqpidvnnvAQRSKMLLDQYKKKAQLYRTNVLFAPLGDDfryettfdtHA 188 *********99*********99************************************************************************ PP Glyco_hydro_38N 220 gggpteellekinrlqekeslpkvqygtpseyfdalek............lptkdsddfpty 269 +++++++++++in e+++kvq+gt+s+yf+al k +p+ s+df ty FUN_001012-T2 189 QFTNYQRIMDYIN--SHPEMKAKVQFGTLSDYFNALFKatgtepggqpknFPAL-SGDFYTY 247 *************..445689***************998888887777777777.7777777 PP >> Glyco_hydro_38C Glycosyl hydrolases family 38 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 1 6.6e+03 37 66 .. 243 274 .. 235 290 .. 0.76 2 ? -3.7 0.0 2.7 1.7e+04 67 112 .. 390 440 .. 379 455 .. 0.60 3 ! 115.8 0.0 6.7e-37 4.3e-33 1 206 [] 515 721 .. 515 721 .. 0.94 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1 Glyco_hydro_38C 37 qfqlyedkpg..ssdawdfrpdyeekplevke 66 f y d+ + +s+ + rp+y++ e+++ FUN_001012-T2 243 DFYTYADREDhyWSGYYTSRPFYKNLDRELES 274 57788888888777888888999998877776 PP == domain 2 score: -3.7 bits; conditional E-value: 2.7 Glyco_hydro_38C 67 ksvevveegplvaevrvklkieeseisqeirly........kgskrlefeteVd 112 k+v+++++ p + +v +++ ++ +q+++l +s e+ ++V+ FUN_001012-T2 390 KEVITLSDTP---RAVVFYNSLTTTREQVVSLHisdpevmvSDSDGAEIASQVN 440 5666666666...33334444445667777777656666666666666666665 PP == domain 3 score: 115.8 bits; conditional E-value: 6.7e-37 Glyco_hydro_38C 1 leNgllkveidnetGtlksiydkeasrevlaekvgnqfqlyedkpg..ssdawdfrpdyeekplevkeksvevveegplvaevrvklkieesei 92 leN+ +k+e++ ++G+lk+i++k+++ + f y +k + +s+a++f pd + ++ e++ + v +g+l +evrv l + FUN_001012-T2 515 LENDEMKLEFSGASGLLKTITHKKDGTVTE---AAIDFATYGTKSSgdRSGAYLFLPDGPAVTHSKGEQPAIYVIRGKLMQEVRVALPN----V 601 79********************99998876...5899****9998888***************************************99....8 PP Glyco_hydro_38C 93 sqeirly....kgskrlefeteVdwg...erevllkvafpvdi.qaefatdengfgvikRptdkntswekakfevpiqsfvdlsdssygvsvln 178 +++rly ++ + ++++++Vd++ ++e+++++++ v++ + ef+td ngf+++kR+t ++ + +++ + p +s+++l+d+s+++++l+ FUN_001012-T2 602 VHVVRLYsvpgPERRMVDIQNKVDIKnlvNKELVMRIKSSVKNsNREFYTDLNGFQMQKRKTLDKIPIQANFY--PLPSMAFLQDKSTRLTLLS 693 *****************************************986889******************55555555..******************* PP Glyco_hydro_38C 179 dskyGvssekdgqleLsLlRrplypdpr 206 + Gv+s ++g+ ++ L+Rr++++d+r FUN_001012-T2 694 SQPNGVASLHQGEFQVVLDRRLYQDDNR 721 ********66****************86 PP >> Alpha-mann_mid Alpha mannosidase middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.4 0.1 1.5e-25 9.6e-22 1 96 [] 253 357 .. 253 357 .. 0.88 Alignments for each domain: == domain 1 score: 77.4 bits; conditional E-value: 1.5e-25 Alpha-mann_mid 1 elhrgtyTsraklKrlnrkleslLreaellss........aa.vskgyeypkeeleelwkalllnQfHDilpGssikeVyedaeeeleealkele 86 ++++g+yTsr+++K l+r+les+ r+ae+++s + +s +e+ + l++++++l+l+Q+HD ++G++++ V+ d+ +++ ++l+ ++ FUN_001012-T2 253 HYWSGYYTSRPFYKNLDRELESKHRAAEIIFSlaeshvrhRGsSSFPVEKLYGLLTKARQNLALFQHHDGITGTAKDFVVVDYGQRMLQSLNDVQ 347 69******************************877765441133445566667789*************************************** PP Alpha-mann_mid 87 klleealrkL 96 ++++e+++ L FUN_001012-T2 348 SVIQESAQLL 357 ******9976 PP >> Laman-like_dom Lysosomal alpha-mannosidase-like, central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.8 0.0 3.7e-13 2.4e-09 6 46 .] 439 472 .. 435 472 .. 0.91 Alignments for each domain: == domain 1 score: 37.8 bits; conditional E-value: 3.7e-13 Laman-like_dom 6 vpvpswkrvlvktiepqssstkyeLvFkAsVPPLGfstYsV 46 v v+ w++ + ++s++kye++F A+VP+LG++tY+V FUN_001012-T2 439 VNVW-WDH------RNRISTAKYEVLFVAKVPALGLTTYFV 472 5799.999......889***********************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (899 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 574 (0.0224702); expected 510.9 (0.02) Passed bias filter: 512 (0.0200431); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 8755.04 // Query: FUN_001013-T1 [L=229] Description: FUN_001013 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-15 56.6 0.6 8.2e-15 56.0 0.6 1.3 1 CS CS domain 1.3e-07 32.2 4.7 1.3e-07 32.2 4.7 2.0 2 Siah-Interact_N Siah interacting protein, N terminal 0.00024 21.7 3.3 0.0003 21.3 1.4 2.0 2 SGS SGS domain ------ inclusion threshold ------ 0.21 12.3 8.5 0.12 13.1 3.5 2.5 2 MYO10_CC Unconventional myosin-X coiled coil domain Domain annotation for each model (and alignments): >> CS CS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.0 0.6 1.3e-18 8.2e-15 2 78 .] 80 159 .. 79 159 .. 0.96 Alignments for each domain: == domain 1 score: 56.0 bits; conditional E-value: 1.3e-18 CS 2 kydWyQtldeVtitipvkka.gvkkkdvkveikkrs..lkvki.kgknekliiegeLfkeIdpeesswtieskkieitLkK 78 +y W+Q+ + V+i+i+++++ + ++++++ +++k+s l+v kgkn+++ + + L+++I pe+ss++i++ k+ +LkK FUN_001013-T1 80 SYAWDQSAKFVKIYITLPEVeTLPEENISSKFTKSSieLRVLGlKGKNHQFQMIH-LLHPIIPESSSVKIKTGKVSMLLKK 159 79**********************************88888888**********9.************************9 PP >> Siah-Interact_N Siah interacting protein, N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.2 4.7 2.1e-11 1.3e-07 3 68 .. 4 71 .. 2 80 .. 0.76 2 ? -1.5 0.1 0.71 4.6e+03 42 61 .. 169 187 .. 152 201 .. 0.62 Alignments for each domain: == domain 1 score: 32.2 bits; conditional E-value: 2.1e-11 Siah-Interact_N 3 ieelqlDleElksLlekAtRkrVkdlLsieirKLeteilklkekqkakaqqksq..lleeekpsakva 68 ++lq eEl+sLl++AtR+rVk lL+ e ++e ei+ +++ ++ + + + +e ++p+ k++ FUN_001013-T1 4 AQDLQGTKEELQSLLSTATRSRVKKLLQDELERVEREIIDAEKQGANGSAEVLNetEVEPKRPIVKKP 71 56777788******************************988887777666554422345555555544 PP == domain 2 score: -1.5 bits; conditional E-value: 0.71 Siah-Interact_N 42 klkekqkakaqqksqlleee 61 ++ e++ka++q+ + e++ FUN_001013-T1 169 TSTENLKATKQEPKY-DESK 187 445555666665555.3444 PP >> SGS SGS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.34 2.2e+03 50 79 .. 47 76 .. 4 78 .. 0.63 2 ! 21.3 1.4 4.8e-08 0.0003 2 53 .. 164 220 .. 163 225 .. 0.78 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.34 SGS 50 veSnGtvLstnWeevkkkkvetkpPegmea 79 + nG++ n +ev+ k+ +k P+++ a FUN_001013-T1 47 QGANGSAEVLNETEVEPKRPIVKKPQATMA 76 445777777777777777777777776655 PP == domain 2 score: 21.3 bits; conditional E-value: 4.8e-08 SGS 2 dWdklekeeekeekeekk.....eegdaalnklFkklYkdadedtrrammKSfveSn 53 +W+ l+++e+ + +++++ ++ ++++ l +k+Y+++d++++r + K ++eS FUN_001013-T1 164 NWSCLTSTENLKATKQEPkydesKDPGESIMGLMRKMYDEGDDEMKRTIAKAWTESR 220 7888887776443333334555566788999************************95 PP >> MYO10_CC Unconventional myosin-X coiled coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 3.5 1.8e-05 0.12 17 52 .] 5 40 .. 2 61 .. 0.98 2 ? 1.0 0.2 0.11 6.8e+02 19 33 .. 157 171 .. 155 180 .. 0.74 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 1.8e-05 MYO10_CC 17 erLqrqkedqvslltetsleelqrlrdeElrrLEkE 52 ++Lq ke+ sll +++ + ++l +El+r E E FUN_001013-T1 5 QDLQGTKEELQSLLSTATRSRVKKLLQDELERVERE 40 89********************************98 PP == domain 2 score: 1.0 bits; conditional E-value: 0.11 MYO10_CC 19 Lqrqkedqvslltet 33 L++ +e++ s+lt t FUN_001013-T1 157 LKKEREENWSCLTST 171 788888888888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (229 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1207 (0.04725); expected 510.9 (0.02) Passed bias filter: 637 (0.0249364); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2295.37 // Query: FUN_001014-T1 [L=197] Description: FUN_001014 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-52 175.5 2.4 9.3e-52 175.2 2.4 1.1 1 Clat_adaptor_s Clathrin adaptor complex small chain Domain annotation for each model (and alignments): >> Clat_adaptor_s Clathrin adaptor complex small chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 175.2 2.4 3.6e-56 9.3e-52 1 141 [. 1 147 [. 1 148 [. 0.94 Alignments for each domain: == domain 1 score: 175.2 bits; conditional E-value: 3.6e-56 Clat_adaptor_s 1 mvkaililnkkgklrlakfytavddkkkqklieevialvsaRdaklsnive......ledlkvvYkryasLYFvvivdeqdnelillelihlfve 89 m+kail++n++gk+rl+kf+ +++++ ++++i+e ++vs Rd +++n++e +d+k++Y++ya+LYFv++vd+ ++el +l+li++fve FUN_001014-T1 1 MIKAILVFNNHGKPRLTKFFAHYSEDMQHQIIRETFHIVSRRDDNVCNFLEggtligGSDFKIIYRHYATLYFVFCVDSSESELGILDLIQVFVE 95 89********************************************99988333322478*********************************** PP Clat_adaptor_s 90 sLdkyfgnVceldlvfnfekvylildEivsgGeiletskkevlkrvelldel 141 +Ldk+f+nVceldl+f ++kv+ il+Eiv+gG++let+ +e+l ++e ++l FUN_001014-T1 96 TLDKCFENVCELDLIFHMDKVHYILQEIVMGGMVLETNMSEILTHIEAQNKL 147 **********************************************999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (197 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 824 (0.0322568); expected 510.9 (0.02) Passed bias filter: 675 (0.026424); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 1911.57 // Query: FUN_001016-T1 [L=875] Description: FUN_001016 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-17 63.3 0.7 8e-17 62.3 0.7 1.4 1 CRAL_TRIO_2 Divergent CRAL/TRIO domain 1.1e-10 42.5 4.3 1.1e-10 42.5 4.3 3.0 3 BNIP2 Bcl2-/adenovirus E1B nineteen kDa-interacting pr 3.3e-06 27.5 0.2 6.2e-06 26.6 0.2 1.4 1 CRAL_TRIO CRAL/TRIO domain Domain annotation for each model (and alignments): >> CRAL_TRIO_2 Divergent CRAL/TRIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.3 0.7 9.4e-21 8e-17 3 124 .. 729 854 .. 727 864 .. 0.86 Alignments for each domain: == domain 1 score: 62.3 bits; conditional E-value: 9.4e-21 CRAL_TRIO_2 3 pVlvfiskll...kasld.....dlerllfyllktlseklkgkp.fvvvvdhtgvtsenfpslsllkklydllprklkknlkavyvvhpstflktv 89 +++v+ +++l +e+l+fy+++t+ e l + + +v+ g++++n p +++k++y+l++ lkk+ k++++vh+++ lk + FUN_001016-T1 729 TIIVIAACYLpdrG---LsnydyLMEQLFFYIISTM-ELLAVHEeYYLVYLNGGTRQHNMPYVAWMKRFYQLIEGGLKKRMKEMFIVHANFRLKVI 820 67888899995541...244556899**********.77555555*************************************************** PP CRAL_TRIO_2 90 lktlgsllgskklkkkvhyvssleelaegidkeel 124 + tl ++++ + +++k+++v sl l++ i+ + + FUN_001016-T1 821 I-TLAKPFLNAVFWRKLIFVHSLGSLSSRIPVDYI 854 *.************************988875555 PP >> BNIP2 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 1.3 1.8 1.5e+04 12 12 .. 59 59 .. 7 112 .. 0.56 2 ? -1.8 0.2 0.62 5.3e+03 20 73 .. 152 206 .. 124 232 .. 0.63 3 ! 42.5 4.3 1.3e-14 1.1e-10 42 136 .. 640 725 .. 609 726 .. 0.64 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.8 BNIP2 12 l 12 FUN_001016-T1 59 T 59 0 PP == domain 2 score: -1.8 bits; conditional E-value: 0.62 BNIP2 20 dsllsatlsessddesdleddl.dinvddletpsdsdslefpesgneleweddlp 73 ++ + +t+ es +d+sdl+d+ ++ + s+ ++f ++g+ e ++d+ FUN_001016-T1 152 ENGMWNTAVESIQDSSDLKDKTiGQELSVSNVSSNVGCTSFSTNGDRRESDEDII 206 4444445555667777777765466666666666666666666777777766655 PP == domain 3 score: 42.5 bits; conditional E-value: 1.3e-14 BNIP2 42 dinvddletpsdsdslefpesgneleweddlpklke......aesaseaaesleeltaedevddsGrrWrtfvigeqeqrvdmkviePYkrVlShG 131 + + + e d+d+++ d + + +++ +l+e + ++++ ds rW t+ + ++e+ d+k +ePY++V+ShG FUN_001016-T1 640 EYEYEGDEEEVDDDDID---------NGD------StieqegEIYGDDEQGHLHEKMISEVNADSRFRWHTVSVNGREKVLDLKLLEPYMKVISHG 720 23333333333333333.........222......12222223334555567777777888888879***************************** PP BNIP2 132 GYygd 136 GY+ d FUN_001016-T1 721 GYFSD 725 ***98 PP >> CRAL_TRIO CRAL/TRIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.2 7.2e-10 6.2e-06 68 147 .. 779 854 .. 721 856 .. 0.77 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 7.2e-10 CRAL_TRIO 68 lslskmdkkplsllkkiikilqdnyperlgkilivnaPkifnviwklikpfldpktreKikflknsneeeLekyidpeql 147 + +m+ ++ +k++ ++++ r+++++iv+a + ++vi++l+kpfl+ ++ +K+ f+ + +L+++i+ +++ FUN_001016-T1 779 TRQHNMP--YVAWMKRFYQLIEGGLKKRMKEMFIVHANFRLKVIITLAKPFLNAVFWRKLIFV--HSLGSLSSRIPVDYI 854 3333444..48999*************************************************..66788*****99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (875 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 895 (0.0350362); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.42s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 8436.48 // Query: FUN_001016-T2 [L=755] Description: FUN_001016 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-10 42.5 5.3 1.1e-10 42.5 5.3 3.2 3 BNIP2 Bcl2-/adenovirus E1B nineteen kDa-interacting prote Domain annotation for each model (and alignments): >> BNIP2 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 1.6 0.51 1.3e+04 8 8 .. 52 52 .. 4 113 .. 0.56 2 ? -1.6 0.4 0.18 4.5e+03 20 73 .. 152 206 .. 123 235 .. 0.64 3 ! 42.5 5.3 4.3e-15 1.1e-10 40 136 .. 638 725 .. 512 726 .. 0.74 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.51 BNIP2 8 P 8 P FUN_001016-T2 52 P 52 0 PP == domain 2 score: -1.6 bits; conditional E-value: 0.18 BNIP2 20 dsllsatlsessddesdleddl.dinvddletpsdsdslefpesgneleweddlp 73 ++ + +t+ es +d+sdl+d+ ++ + s+ ++f ++g+ e ++d+ FUN_001016-T2 152 ENGMWNTAVESIQDSSDLKDKTiGQELSVSNVSSNVGCTSFSTNGDRRESDEDII 206 4444445555667777777765466666666666666666667777777777655 PP == domain 3 score: 42.5 bits; conditional E-value: 4.3e-15 BNIP2 40 dldinvddletpsdsdslefpesgneleweddlpklke......aesaseaaesleeltaedevddsGrrWrtfvigeqeqrvdmkviePYkrVlS 129 d + + + e d+d+++ d + + +++ +l+e + ++++ ds rW t+ + ++e+ d+k +ePY++V+S FUN_001016-T2 638 DSEYEYEGDEEEVDDDDID---------NGD------StieqegEIYGDDEQGHLHEKMISEVNADSRFRWHTVSVNGREKVLDLKLLEPYMKVIS 718 2222222222222222333.........222......12333323344555667777777888888879*************************** PP BNIP2 130 hGGYygd 136 hGGY+ d FUN_001016-T2 719 HGGYFSD 725 *****98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (755 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1104 (0.0432179); expected 510.9 (0.02) Passed bias filter: 511 (0.0200039); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 7353.16 // Query: FUN_001017-T1 [L=455] Description: FUN_001017 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-06 29.0 0.1 3.9e-05 24.0 0.1 2.3 1 APH Phosphotransferase enzyme family 1.1e-05 25.4 0.2 0.00012 22.1 0.2 2.4 1 EcKL Ecdysteroid kinase-like family ------ inclusion threshold ------ 0.07 13.7 0.0 1.4 9.6 0.0 2.3 2 E2F_CC-MB E2F transcription factor CC-MB domain Domain annotation for each model (and alignments): >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.1 4.5e-09 3.9e-05 145 232 .. 274 381 .. 169 388 .. 0.70 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 4.5e-09 APH 145 drleeleeqllaallallpa..elppvlvHgDlhpgNllvd.................dggrvsGviDFedaglGdpayDlaillnd.wgeelgae 220 ++ +l + +++ l++l+ ++p++ vH D+ p+N+ ++ + rvs++ D+e+a++ p +Dl+ +l++ ++ + + + FUN_001017-T1 274 TERTRLIKSFIDKLDQLWQVidSFPQTMVHYDFTPRNVCLRkhnlhednqrsvfisnnNLCRVSCIYDWEMATIHAPQHDLVEFLAFvLPAKTDVT 369 2445566669999999999999*******************9999974333333332222356**********************98899999999 PP APH 221 lleallaaygag 232 + l++ y++ FUN_001017-T1 370 TRIKLVRFYQRQ 381 999988888744 PP >> EcKL Ecdysteroid kinase-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.2 1.4e-08 0.00012 70 287 .. 163 384 .. 138 389 .. 0.76 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 1.4e-08 EcKL 70 eagdefklapkcyyaeeeeeee..vlileDLs..ekgyknadrl.kgldlehtklvlkkLAkfHAaSaalkeekpevlkelkkglleedylnsalk 160 ++++ +++ap++y++ ++++e + ++eDL+ +++ +d + ++e+++ vl+ +A fH + + + + lk++++ y s FUN_001017-T1 163 SNRKFTDIAPQVYHTICDPSKElfIAVMEDLTgrVTHFNAIDNApEVWNQEDIQVVLRDIAGFHSIHLGDVTH-------LKSEPWMCVYSGS--- 248 455667899999999999886611458****722579****9973567****************776655555.......6767776666666... PP EcKL 161 eefeelleellkaaaealkeelpelekekekleklkenlfdrllelveekeeefnvLnHGDlwvnNimfkydeeg.epedvilv............ 243 + + l+++ a++ + ++++p++ +++ +l+++++d+l +l++ ++ ++++H D+ +N+ ++ + + + ++ +++ FUN_001017-T1 249 --VMQALRGFWLALLSQNRANFPSI--WTTERTRLIKSFIDKLDQLWQVIDSFPQTMVHYDFTPRNVCLRKHNLHeDNQRSVFIsnnnlcrvsciy 340 ..45666666666666666666776..44556788999*****************************88754332233433333333333333445 PP EcKL 244 DFQlsrygSpalDLlyflytsteeelrrekfdellriYhesLve 287 D+ ++ + p DL+ fl + + +l+r+Y+++L + FUN_001017-T1 341 DWEMATIHAPQHDLVEFLAFVLPAKTDVTTRIKLVRFYQRQLER 384 *****************************************986 PP >> E2F_CC-MB E2F transcription factor CC-MB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.063 5.4e+02 28 51 .. 135 159 .. 125 170 .. 0.74 2 ? 9.6 0.0 0.00016 1.4 26 69 .. 313 356 .. 304 373 .. 0.86 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.063 E2F_CC-MB 28 nltedeen.kklaYvtyeDirsiks 51 ++++ ++ ++ +Y +y+D+r+ik FUN_001017-T1 135 DVSKYADVfQRVSYFRYSDVREIKL 159 565666666889**********985 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00016 E2F_CC-MB 26 lknltedeenkklaYvtyeDirsiksfkeqtviaikApegtkle 69 l++++ +e+n++ +++++++++++++ + + i Ap++ +e FUN_001017-T1 313 LRKHNLHEDNQRSVFISNNNLCRVSCIYDWEMATIHAPQHDLVE 356 5666667788889*************************986666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (455 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 598 (0.0234097); expected 510.9 (0.02) Passed bias filter: 496 (0.0194167); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4323.44 // Query: FUN_001017-T2 [L=439] Description: FUN_001017 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-06 29.1 0.1 3.7e-05 24.1 0.1 2.3 1 APH Phosphotransferase enzyme family 1e-05 25.5 0.2 8.1e-05 22.6 0.2 2.5 1 EcKL Ecdysteroid kinase-like family ------ inclusion threshold ------ 0.064 13.9 0.0 1.3 9.7 0.0 2.3 2 E2F_CC-MB E2F transcription factor CC-MB domain Domain annotation for each model (and alignments): >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.1 4.3e-09 3.7e-05 145 232 .. 258 365 .. 154 372 .. 0.70 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 4.3e-09 APH 145 drleeleeqllaallallpa..elppvlvHgDlhpgNllvd.................dggrvsGviDFedaglGdpayDlaillnd.wgeelgae 220 ++ +l + +++ l++l+ ++p++ vH D+ p+N+ ++ + rvs++ D+e+a++ p +Dl+ +l++ ++ + + + FUN_001017-T2 258 TERTRLIKSFIDKLDQLWQVidSFPQTMVHYDFTPRNVCLRkhnlhednqrsvfisnnNLCRVSCIYDWEMATIHAPQHDLVEFLAFvLPAKTDVT 353 2445566669999999999999*******************9999974333333332222356**********************98899999999 PP APH 221 lleallaaygag 232 + l++ y++ FUN_001017-T2 354 TRIKLVRFYQRQ 365 999988888744 PP >> EcKL Ecdysteroid kinase-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.2 9.5e-09 8.1e-05 66 287 .. 143 368 .. 92 373 .. 0.77 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 9.5e-09 EcKL 66 allreagdefklapkcyyaeeeeeee..vlileDLs..ekgyknadrl.kgldlehtklvlkkLAkfHAaSaalkeekpevlkelkkglleedyln 156 l+ ++++ +++ap++y++ ++++e + ++eDL+ +++ +d + ++e+++ vl+ +A fH + + + + lk++++ y FUN_001017-T2 143 LLSLSNRKFTDIAPQVYHTICDPSKElfIAVMEDLTgrVTHFNAIDNApEVWNQEDIQVVLRDIAGFHSIHLGDVTH-------LKSEPWMCVYSG 231 4555556678899999999999986611458****722579****9973567****************776655555.......676777666666 PP EcKL 157 salkeefeelleellkaaaealkeelpelekekekleklkenlfdrllelveekeeefnvLnHGDlwvnNimfkydeeg.epedvilv........ 243 s + + l+++ a++ + ++++p++ +++ +l+++++d+l +l++ ++ ++++H D+ +N+ ++ + + + ++ +++ FUN_001017-T2 232 S-----VMQALRGFWLALLSQNRANFPSI--WTTERTRLIKSFIDKLDQLWQVIDSFPQTMVHYDFTPRNVCLRKHNLHeDNQRSVFIsnnnlcrv 320 6.....45666666666666666666776..44556788999*****************************8875433223343333333333333 PP EcKL 244 ....DFQlsrygSpalDLlyflytsteeelrrekfdellriYhesLve 287 D+ ++ + p DL+ fl + + +l+r+Y+++L + FUN_001017-T2 321 sciyDWEMATIHAPQHDLVEFLAFVLPAKTDVTTRIKLVRFYQRQLER 368 3445*****************************************986 PP >> E2F_CC-MB E2F transcription factor CC-MB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.061 5.2e+02 28 51 .. 119 143 .. 109 154 .. 0.74 2 ? 9.7 0.0 0.00015 1.3 26 69 .. 297 340 .. 288 357 .. 0.86 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.061 E2F_CC-MB 28 nltedeen.kklaYvtyeDirsiks 51 ++++ ++ ++ +Y +y+D+r+ik FUN_001017-T2 119 DVSKYADVfQRVSYFRYSDVREIKL 143 565666666889**********985 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00015 E2F_CC-MB 26 lknltedeenkklaYvtyeDirsiksfkeqtviaikApegtkle 69 l++++ +e+n++ +++++++++++++ + + i Ap++ +e FUN_001017-T2 297 LRKHNLHEDNQRSVFISNNNLCRVSCIYDWEMATIHAPQHDLVE 340 5666667788889*************************986666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (439 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 567 (0.0221961); expected 510.9 (0.02) Passed bias filter: 468 (0.0183206); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.42s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4230.20 // Query: FUN_001018-T1 [L=535] Description: FUN_001018 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-10 39.3 0.2 4.7e-09 36.5 0.1 2.5 3 DEP Domain found in Dishevelled, Egl-10, and Pleckst ------ inclusion threshold ------ 0.074 14.0 2.7 0.085 13.8 0.1 2.4 2 Mvb12 ESCRT-I subunit Mvb12 0.077 12.9 2.2 2.3 8.0 0.1 2.5 2 Fanconi_A_N Fanconi anaemia group A protein N terminus Domain annotation for each model (and alignments): >> DEP Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 0.87 7.4e+03 34 49 .. 18 33 .. 13 33 .. 0.80 2 ! 36.5 0.1 5.5e-13 4.7e-09 2 72 .] 38 119 .. 37 119 .. 0.96 3 ? -1.8 0.0 0.5 4.3e+03 21 41 .. 494 516 .. 494 520 .. 0.72 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 0.87 DEP 34 ktreeAvelgqkLlek 49 +++ +A +++++L+e+ FUN_001018-T1 18 HEPFKATKIWNDLVEH 33 67789********987 PP == domain 2 score: 36.5 bits; conditional E-value: 5.5e-13 DEP 2 lklkdrrkhlktypncftGseavdWLldnle.......iktreeAvelgqkLlekgliehvtdkhst.....FkdskyalYrf 72 ++ + rr+++ y+ncf G +++++L+ ++ tr++ ++q Llek++ie vt+++s+ F+ + + lYrf FUN_001018-T1 38 VEHRRRRWKFQYYENCFRGGDVIEVLHSYIQsnphlsnDATRDQVRCFCQILLEKRIIECVTTENSKtksycFEGG-NKLYRF 119 67799**********************************************************99999********.9****9 PP == domain 3 score: -1.8 bits; conditional E-value: 0.5 DEP 21 seavdWLldnle..iktreeAve 41 s++ +++dnl+ k+ ee ++ FUN_001018-T1 494 SDMMTFIMDNLHmsLKEKEERLK 516 689999***99976666666555 PP >> Mvb12 ESCRT-I subunit Mvb12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.3 0.61 5.2e+03 26 65 .. 8 47 .. 2 55 .. 0.49 2 ? 13.8 0.1 1e-05 0.085 17 78 .. 471 533 .. 454 535 .] 0.87 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.61 Mvb12 26 elkleelqptkemlep...wikecdeivesleqhdesgkeFdk 65 + +le+++ ++e +++ w + +++ ++e++ +++ FUN_001018-T1 8 NTELESDNMAHEPFKAtkiWNDLVEHLRTNVEHR---RRRWKF 47 5555555555555554111555555555555544...444444 PP == domain 2 score: 13.8 bits; conditional E-value: 1e-05 Mvb12 17 eklkklevpelkleelqptkemlepwike.cdeivesleqhdesgkeFdkWYkekyLskkPpG 78 + ++l+v+e++ ++lq+t+e l+ +++ d++ sl++++e+ k F+k + +L + P G FUN_001018-T1 471 KVSRQLSVQEYQQQKLQTTNESLSDMMTFiMDNLHMSLKEKEERLKVFQKHHTAVFLLHFPDG 533 67789******************999987369*************************999998 PP >> Fanconi_A_N Fanconi anaemia group A protein N terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.00027 2.3 180 242 .. 331 394 .. 316 404 .. 0.88 2 ? 3.9 0.3 0.0049 42 83 125 .. 475 517 .. 447 530 .. 0.76 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00027 Fanconi_A_N 180 ertdeLlttlyrrlfvklspeelleaLqevletsevnwkhvLslvstlvvclpea.qqlikdyl 242 +++++Ll y +l++ l p++l + ++ v+ t +w + s++ l+ +l ++ ++ +k++l FUN_001018-T1 331 AGIQQLLLEYYGSLLDSLIPSNLTDLVNAVISTLVDDWSKIKSFLPLLALMLSTNqRKHLKNLL 394 68899***************************************99999999988456666665 PP == domain 2 score: 3.9 bits; conditional E-value: 0.0049 Fanconi_A_N 83 elrsaaedeklslvltavLqrmlsfllealaanlqeeslayka 125 +l+ + ++++ ++ ++ L +m++f++++l+ +l+e++ +k FUN_001018-T1 475 QLSVQEYQQQKLQTTNESLSDMMTFIMDNLHMSLKEKEERLKV 517 4555667778888888889999999999999888887776664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (535 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1483 (0.0580544); expected 510.9 (0.02) Passed bias filter: 906 (0.0354668); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.37s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 5255.93 // Query: FUN_001019-T1 [L=1167] Description: FUN_001019 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-80 270.5 0.3 4.9e-80 268.9 0.3 1.9 1 USP47_C Ubiquitin carboxyl-terminal hydrolase 47 C 3.9e-63 213.9 1.7 1e-62 212.5 1.7 1.8 1 UCH Ubiquitin carboxyl-terminal hydrolase 2.3e-33 114.6 0.0 1.8e-30 105.3 0.0 3.2 3 Ubiquitin_USP47_N Ubiquitin carboxyl-terminal hydrolase 47, 3.3e-21 76.7 3.5 5.3e-21 76.0 0.9 2.7 2 UCH_1 Ubiquitin carboxyl-terminal hydrolase 0.00032 21.6 0.2 0.35 11.8 0.1 3.5 3 Ubiquitin_2 Ubiquitin-like domain ------ inclusion threshold ------ 0.012 15.8 3.0 10 6.5 0.0 5.1 6 ubiquitin Ubiquitin family 0.058 13.4 0.1 0.12 12.3 0.1 1.5 1 tRNA-synt_1_2 Leucyl-tRNA synthetase, editing domain 0.065 13.2 0.2 0.21 11.6 0.2 1.9 1 DUF8118 Domain of unknown function (DUF8118) 0.15 13.2 0.1 76 4.5 0.0 3.7 4 OTU1_UBXL OTU1, UBXL domain Domain annotation for each model (and alignments): >> USP47_C Ubiquitin carboxyl-terminal hydrolase 47 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 268.9 0.3 1.7e-83 4.9e-80 2 240 .] 920 1159 .. 919 1159 .. 0.99 Alignments for each domain: == domain 1 score: 268.9 bits; conditional E-value: 1.7e-83 USP47_C 2 vkvyqllvnetevfkylvesivakdmtvleskkeileeikeqvdldipldkcrlrkktwknpgtvyldeqvydkdialyanfevfvevldepek 95 +k+++l e e++kyl ++iv+ +mtv++ k+ + +ei e++d dipl+ +rlr+k+wknpg vy deqv+++ i++ya fevf+e l++pe+ FUN_001019-T1 920 LKIFMLNATEKEPVKYLFDWIVSDGMTVKQCKELLHPEICERCDTDIPLENLRLRRKSWKNPGRVYTDEQVFEDSIKVYASFEVFLEILEGPER 1013 79******************************************************************************************** PP USP47_C 96 vtkatqlavyvrrWrpskysldrfqevvldkrtleelkkklseiseiPveaidiakgkGsfPcevsvleve.neleWnpaaqslsdtplyifed 188 +t+++ l +y+r+W+ps+++ld+ +evvl++ t+e lk+k+se+s+i ve+++++kg+G fPce s+le++ n++ W + +l+ +pl i +d FUN_001019-T1 1014 MTSTEYLSLYLRQWHPSTLTLDNPKEVVLKESTVEALKEKMSELSGIAVEDLELCKGRGQFPCEASILEIHgNDFGWASDMLQLRSIPLLINDD 1107 **********************************************************************7589******************** PP USP47_C 189 Gaviyykdnreklkelteeekkeiekkenvriaklsskssssprkeralkiy 240 Gav+yy+d++e+l e+tee+k+ei ken + a+ +++ ke+alkiy FUN_001019-T1 1108 GAVVYYRDKNEELLEITEEKKQEILSKENAKSASSTTRGGRFSHKEKALKIY 1159 ******************************99999999999**********9 PP >> UCH Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 212.5 1.7 3.6e-66 1e-62 1 254 [] 160 550 .. 160 550 .. 0.95 Alignments for each domain: == domain 1 score: 212.5 bits; conditional E-value: 3.6e-66 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 1 vGlkNlgntCymnsvlQaLlsipelrdlllrieeekedseeekeinllkalaklfkelqkkkksssvkPkklkkllgklneefsgykqqDaqEfle 96 vGl+N+ +tCy+ns+lQ L+++pe+r++++r+e + +++e k+ ++++l+klf lq ++++++v++++++k++g+ ++e +++q+D+qE+++ FUN_001019-T1 160 VGLVNQAMTCYLNSLLQTLFMTPEFRNAIYRWEFTGSEDEAGKS--IPYQLQKLFLLLQ-ASSKRAVETTDVTKSFGWDSSE--AWQQHDVQELCR 250 6*******************************999999998877..9********8888.999*******************..9*********** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................... RF UCH 97 flLdqlheklnkwekaskeeeslitdlFrgqlksrlkckeceee.................................................... 140 +++d l++k+++ + +++li++l++g+lk+++kc++c++e FUN_001019-T1 251 VMFDALESKFKN-----TVQDDLINKLYQGKLKDYVKCQQCGYEsartdtyldiplairpfgsltalgsvenalqnfiapevlndsnqyfcekcne 341 ************.....9****************************************************************************** PP ......xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................... RF UCH 141 ......klkikrlPevLiihlkRfsynre..vkeKlntevefpeeldlseylaeeekektkekkk............................... 197 lk+ ++P L+++lkRf ++ + Kln++++fpe+l l+++++ee +e +++ + FUN_001019-T1 342 kcdahkGLKFISFPYLLTLQLKRFAFDYAtlHRVKLNDRMTFPEYLYLKDFVSEEHEETDADEDSsvkgdsqsstetdsgvsegcsdngmsteeed 437 **************************9888899*******************99998877766669****************************** PP ......................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............. RF UCH 198 ......................................YeLvavvvHsGslssGHYiayikaeeknkWvkfdDekvsevdee.............. 241 YeL+++++HsGs+++GHY+ayik+ e n+W++f+D++v++v ++ FUN_001019-T1 438 fdnarggadpvglasenleeseemltngitdnmkgpycYELFSIMIHSGSATGGHYYAYIKSFETNQWYCFNDQSVTRVYDDdiertyggvessrh 533 *******************************************************************************99866666666655555 PP ..xxxxx.....xxxxxxxx RF UCH 242 ..kevls.....esayiLfY 254 + s ++ay+L+Y FUN_001019-T1 534 yyS---SvytssTNAYMLMY 550 551...0555669******9 PP >> Ubiquitin_USP47_N Ubiquitin carboxyl-terminal hydrolase 47, ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.3 0.0 6.4e-34 1.8e-30 1 97 [. 21 117 .. 21 120 .. 0.97 2 ? -3.3 0.0 4.6 1.3e+04 18 44 .. 209 235 .. 205 238 .. 0.81 3 ! 5.4 0.0 0.0085 24 28 81 .. 729 780 .. 717 785 .. 0.90 Alignments for each domain: == domain 1 score: 105.3 bits; conditional E-value: 6.4e-34 Ubiquitin_USP47_N 1 prvlcIvrDmtnaktvnekltlnlpasttvkklfeeVakkfgYepdsfeLvlqrvkngdevelneeeektLeevgfveggkrnfLiltdkdg 92 p+vlcI++D t+++++n+k+t+nlpast+v++l+++ ak+++Y++dsf Lv+++ ++++e+ ln ++ktL+evg+v++gk+n + ++dkdg FUN_001019-T1 21 PTVLCIIKDETTSDWKNSKHTINLPASTPVQELITHAAKEAKYVEDSFLLVWSKPQGNEEILLNAFKDKTLQEVGLVSNGKKNSFLIKDKDG 112 68****************************************************99************************************ PP Ubiquitin_USP47_N 93 eqpkr 97 qp + FUN_001019-T1 113 VQPTK 117 **987 PP == domain 2 score: -3.3 bits; conditional E-value: 4.6 Ubiquitin_USP47_N 18 ekltlnlpasttvkklfeeVakkfgYe 44 +kl l l+as+ +++V k+fg + FUN_001019-T1 209 QKLFLLLQASSKRAVETTDVTKSFGWD 235 788899999999888889999998876 PP == domain 3 score: 5.4 bits; conditional E-value: 0.0085 Ubiquitin_USP47_N 28 ttvkklfeeVakkfgYepdsfeLvlqrvkngdevelneeeektLeevgfveggk 81 +t+k+l++ + ++f +++ +vl+ +e++l + ++k+L+e+gf+ ++k FUN_001019-T1 729 STAKDLHTLIHERFDLPLETLRVVLEG--SYNELKLLDRSDKSLKELGFFRSNK 780 789999999999999999********9..89999***************87765 PP >> UCH_1 Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.0 0.9 1.9e-24 5.3e-21 1 317 [] 160 513 .. 160 513 .. 0.80 2 ? -1.5 0.1 0.76 2.2e+03 127 205 .. 892 969 .. 820 1039 .. 0.72 Alignments for each domain: == domain 1 score: 76.0 bits; conditional E-value: 1.9e-24 UCH_1 1 sGLEthiansYtNslLQllrfipplrnlalshlat..eckkencLlcElgflfdmlekakgkncqasNFlkalssipeasalglleeeeeskkkas 94 +GL ++ ++Y+NslLQ+l+ +p++rn + + t e++ +++ ++l+ lf l+ ++++ ++++ k+++ + ++a + FUN_001019-T1 160 VGLVNQAMTCYLNSLLQTLFMTPEFRNAIYRWEFTgsEDEAGKSIPYQLQKLFLLLQASSKRAVETTDVTKSFGWDS-SEAWQ------------- 241 6999**********************9998765552277777*************************9999998666.22222............. PP UCH_1 95 lssliqsfnrflleqlsseekstkknsseaeseleqllgikaettirclsCgsesekesstlvldliypkkssnekkkknltfssilkssler... 187 ++ +q++ r++ + l+s++k+t + ++ +++l++ k++ ++c++Cg+es ++ + l + l ++ + ++ ++++ l++++ FUN_001019-T1 242 -QHDVQELCRVMFDALESKFKNTVQ-----DDLINKLYQGKLKDYVKCQQCGYESARTDTYLDIPLAI-RPFGSL--TALGSVENALQNFIAPevl 328 .344899************999875.....899*******************************9966.333222..3446888888888888666 PP UCH_1 188 ekttkawCekCkkyqtlesrrtvknlPpvLslnaaltseeelelWkd................................................. 234 +++++ +CekC+++ ++ + + P +L+l ++ + l + FUN_001019-T1 329 NDSNQYFCEKCNEKCDAHKGLKFISFPYLLTLQLKRFAFDYATLHRVklndrmtfpeylylkdfvseeheetdadedssvkgdsqsstetdsgvse 424 68899*********999999999************9844423333336677888888999988888888888888888888888887777766665 PP UCH_1 235 ....knwLpkeigltldkdkl..........................dlklklqeekekeeeeivvYeLvgvVveikdskekkshLvslvkvaese 300 + ++++ l+++ +++ ++ + YeL ++ ++ + s + +h+++++k e+ FUN_001019-T1 425 gcsdN---------------GmsteeedfdnarggadpvglasenleESEEMLTNGITDNMKGPYCYELFSIMIHSG-SAT-GGHYYAYIKSFET- 502 55541...............02333333355555557778888877778888888889999****************.654.9********8555. PP UCH_1 301 aeaekesqWylFNDflV 317 +qWy FND +V FUN_001019-T1 503 ------NQWYCFNDQSV 513 ......8*******877 PP == domain 2 score: -1.5 bits; conditional E-value: 0.76 UCH_1 127 eleqllgikaettirclsCgsesekesstlvldliypkkssnekkkknltfssilkssler....ekttkawCekCkkyqtle 205 +ql++++ ++r + ++ ++ e+ + ++ l++ +ek++ ++ f i+++ + e + +Ce+C + +le FUN_001019-T1 892 LSDQLTSFNDDAKVRVKYSRAPKKGEHQLKIFMLNA-----TEKEPVKYLFDWIVSDGMTVkqckELLHPEICERCDTDIPLE 969 345666666666666666666666666666665522.....344566677777777777654444667788888887766655 PP >> Ubiquitin_2 Ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.8 0.1 0.00012 0.35 14 66 .. 843 896 .. 836 908 .. 0.67 2 ? -4.1 0.0 9 2.6e+04 66 77 .. 936 947 .. 933 954 .. 0.70 3 ? 5.4 0.0 0.013 37 22 46 .. 1043 1067 .. 1039 1079 .. 0.88 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00012 Ubiquitin_2 14 vsserr..fsksltieelKekLelitGtspasmrLel.y.dkddnkvaklddddklL 66 + se+ ++k +t+++lKe L+ +G+sp++ r++ y ++++ ++ kl+d +L FUN_001019-T1 843 KTSEKLypIDKRITLGNLKEILQSEVGCSPEYFRVYRvYsSSQEIEYNKLSD---QL 896 566654115899***********************98344444444444443...34 PP == domain 2 score: -4.1 bits; conditional E-value: 9 Ubiquitin_2 66 LgsYgvedgmri 77 L ++ v+dgm++ FUN_001019-T1 936 LFDWIVSDGMTV 947 667777787776 PP == domain 3 score: 5.4 bits; conditional E-value: 0.013 Ubiquitin_2 22 ksltieelKekLelitGtspasmrL 46 k+ t+e+lKek+ + G+ ++ +L FUN_001019-T1 1043 KESTVEALKEKMSELSGIAVEDLEL 1067 678****************998776 PP >> ubiquitin Ubiquitin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.57 1.6e+03 6 39 .. 35 68 .. 31 73 .. 0.81 2 ? -3.4 0.1 4.3 1.2e+04 42 60 .. 272 289 .. 262 292 .. 0.83 3 ? 3.1 0.0 0.041 1.2e+02 18 45 .. 728 755 .. 721 783 .. 0.80 4 ? 0.9 0.0 0.2 5.7e+02 9 41 .. 845 877 .. 840 887 .. 0.84 5 ? -2.1 0.0 1.7 4.8e+03 18 31 .. 944 957 .. 940 973 .. 0.72 6 ? 6.5 0.0 0.0036 10 16 41 .. 1042 1067 .. 1040 1068 .. 0.88 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.57 ubiquitin 6 ldgkkitlevdesdtvlelKekieekegipaeqq 39 ++++k+t+ ++ s+ v+el + +++ ++ +++ FUN_001019-T1 35 WKNSKHTINLPASTPVQELITHAAKEAKYVEDSF 68 6889**************9888888877766665 PP == domain 2 score: -3.4 bits; conditional E-value: 4.3 ubiquitin 42 iysGkvLeddqtleeygik 60 +y+Gk+ +d + +++g + FUN_001019-T1 272 LYQGKL-KDYVKCQQCGYE 289 699997.999999999865 PP == domain 3 score: 3.1 bits; conditional E-value: 0.041 ubiquitin 18 sdtvlelKekieekegipaeqqrLiysG 45 ++t ++l+ i+e++++p e +r++++G FUN_001019-T1 728 NSTAKDLHTLIHERFDLPLETLRVVLEG 755 78999*********************99 PP == domain 4 score: 0.9 bits; conditional E-value: 0.2 ubiquitin 9 kkitlevdesdtvlelKekieekegipaeqqrL 41 ++ + +d+ t+ +lKe ++++ g +e +r+ FUN_001019-T1 845 SEKLYPIDKRITLGNLKEILQSEVGCSPEYFRV 877 55556788999**************99998886 PP == domain 5 score: -2.1 bits; conditional E-value: 1.7 ubiquitin 18 sdtvlelKekieek 31 tv+++Ke ++ + FUN_001019-T1 944 GMTVKQCKELLHPE 957 56999999998865 PP == domain 6 score: 6.5 bits; conditional E-value: 0.0036 ubiquitin 16 desdtvlelKekieekegipaeqqrL 41 +++tv+ lKek +e gi++e + L FUN_001019-T1 1042 LKESTVEALKEKMSELSGIAVEDLEL 1067 5789****************998765 PP >> tRNA-synt_1_2 Leucyl-tRNA synthetase, editing domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 4.3e-05 0.12 25 98 .. 538 611 .. 528 614 .. 0.84 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 4.3e-05 tRNA-synt_1_2 25 vfttrpdtlyGvtyvalapehplv.eklaekkeevaafieevkkekeaereleekekeGvatglkaihPltgekv 98 v+t+ + y y +ape + +l + +++a++i+++k+++e+er+ +e++++ + +++ hPlt++++ FUN_001019-T1 538 VYTSSTNA-YMLMYRKVAPERNAKfMELGDVPKHIAELIHKLKNHEEMERRRKEMDRSMCKIKIFCEHPLTKKRM 611 77776665.447788899987764156688999**************************************9987 PP >> DUF8118 Domain of unknown function (DUF8118) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.2 7.4e-05 0.21 18 32 .. 278 292 .. 273 298 .. 0.80 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.4e-05 DUF8118 18 arYvRCedCgrEvLt 32 ++Yv C++Cg E+ + FUN_001019-T1 278 KDYVKCQQCGYESAR 292 78**********964 PP >> OTU1_UBXL OTU1, UBXL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.027 76 9 32 .. 37 60 .. 35 67 .. 0.85 2 ? -2.0 0.0 2.9 8.2e+03 20 41 .. 729 750 .. 728 751 .. 0.86 3 ? -2.7 0.0 4.8 1.4e+04 17 37 .. 852 872 .. 850 876 .. 0.82 4 ? 3.8 0.1 0.044 1.3e+02 19 39 .. 1044 1064 .. 1030 1070 .. 0.88 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.027 OTU1_UBXL 9 sgqstitLdddatvgdLleeisek 32 + +ti+L+ ++ v++L+++ +++ FUN_001019-T1 37 NSKHTINLPASTPVQELITHAAKE 60 5679**************998765 PP == domain 2 score: -2.0 bits; conditional E-value: 2.9 OTU1_UBXL 20 atvgdLleeisektgipsfdik 41 +t +dL + i e ++p ++++ FUN_001019-T1 729 STAKDLHTLIHERFDLPLETLR 750 7999********9999988776 PP == domain 3 score: -2.7 bits; conditional E-value: 4.8 OTU1_UBXL 17 dddatvgdLleeisektgips 37 d t+g L+e ++++ g ++ FUN_001019-T1 852 DKRITLGNLKEILQSEVGCSP 872 66789******9999988765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.044 OTU1_UBXL 19 datvgdLleeisektgipsfd 39 ++tv+ L+e+ se +gi+++d FUN_001019-T1 1044 ESTVEALKEKMSELSGIAVED 1064 79***************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1206 (0.0472108); expected 510.9 (0.02) Passed bias filter: 716 (0.028029); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.45u 0.40s 00:00:00.85 Elapsed: 00:00:00.43 # Mc/sec: 10982.64 // Query: FUN_001019-T2 [L=1138] Description: FUN_001019 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-75 253.7 0.6 7.2e-75 252.0 0.6 1.9 1 USP47_C Ubiquitin carboxyl-terminal hydrolase 47 C 3.8e-63 214.0 1.7 9.8e-63 212.6 1.7 1.8 1 UCH Ubiquitin carboxyl-terminal hydrolase 2.2e-33 114.7 0.0 1.7e-30 105.4 0.0 3.2 3 Ubiquitin_USP47_N Ubiquitin carboxyl-terminal hydrolase 47, 2.9e-21 76.9 3.5 5e-21 76.1 0.9 2.7 2 UCH_1 Ubiquitin carboxyl-terminal hydrolase 0.0003 21.7 0.2 0.34 11.9 0.1 3.5 3 Ubiquitin_2 Ubiquitin-like domain ------ inclusion threshold ------ 0.012 15.8 3.1 9.9 6.5 0.0 5.1 6 ubiquitin Ubiquitin family 0.059 13.3 0.1 0.12 12.3 0.1 1.4 1 tRNA-synt_1_2 Leucyl-tRNA synthetase, editing domain 0.062 13.3 0.2 0.2 11.6 0.2 1.9 1 DUF8118 Domain of unknown function (DUF8118) 0.14 13.3 0.1 74 4.5 0.0 3.7 4 OTU1_UBXL OTU1, UBXL domain Domain annotation for each model (and alignments): >> USP47_C Ubiquitin carboxyl-terminal hydrolase 47 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 252.0 0.6 2.5e-78 7.2e-75 2 218 .. 920 1137 .. 919 1138 .] 0.99 Alignments for each domain: == domain 1 score: 252.0 bits; conditional E-value: 2.5e-78 USP47_C 2 vkvyqllvnetevfkylvesivakdmtvleskkeileeikeqvdldipldkcrlrkktwknpgtvyldeqvydkdialyanfevfvevldepek 95 +k+++l e e++kyl ++iv+ +mtv++ k+ + +ei e++d dipl+ +rlr+k+wknpg vy deqv+++ i++ya fevf+e l++pe+ FUN_001019-T2 920 LKIFMLNATEKEPVKYLFDWIVSDGMTVKQCKELLHPEICERCDTDIPLENLRLRRKSWKNPGRVYTDEQVFEDSIKVYASFEVFLEILEGPER 1013 79******************************************************************************************** PP USP47_C 96 vtkatqlavyvrrWrpskysldrfqevvldkrtleelkkklseiseiPveaidiakgkGsfPcevsvleve.neleWnpaaqslsdtplyifed 188 +t+++ l +y+r+W+ps+++ld+ +evvl++ t+e lk+k+se+s+i ve+++++kg+G fPce s+le++ n++ W + +l+ +pl i +d FUN_001019-T2 1014 MTSTEYLSLYLRQWHPSTLTLDNPKEVVLKESTVEALKEKMSELSGIAVEDLELCKGRGQFPCEASILEIHgNDFGWASDMLQLRSIPLLINDD 1107 **********************************************************************7589******************** PP USP47_C 189 Gaviyykdnreklkelteeekkeiekkenv 218 Gav+yy+d++e+l e+tee+k+ei ken FUN_001019-T2 1108 GAVVYYRDKNEELLEITEEKKQEILSKENA 1137 ****************************96 PP >> UCH Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 212.6 1.7 3.5e-66 9.8e-63 1 254 [] 160 550 .. 160 550 .. 0.95 Alignments for each domain: == domain 1 score: 212.6 bits; conditional E-value: 3.5e-66 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 1 vGlkNlgntCymnsvlQaLlsipelrdlllrieeekedseeekeinllkalaklfkelqkkkksssvkPkklkkllgklneefsgykqqDaqEfle 96 vGl+N+ +tCy+ns+lQ L+++pe+r++++r+e + +++e k+ ++++l+klf lq ++++++v++++++k++g+ ++e +++q+D+qE+++ FUN_001019-T2 160 VGLVNQAMTCYLNSLLQTLFMTPEFRNAIYRWEFTGSEDEAGKS--IPYQLQKLFLLLQ-ASSKRAVETTDVTKSFGWDSSE--AWQQHDVQELCR 250 6*******************************999999998877..9********8888.999*******************..9*********** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................... RF UCH 97 flLdqlheklnkwekaskeeeslitdlFrgqlksrlkckeceee.................................................... 140 +++d l++k+++ + +++li++l++g+lk+++kc++c++e FUN_001019-T2 251 VMFDALESKFKN-----TVQDDLINKLYQGKLKDYVKCQQCGYEsartdtyldiplairpfgsltalgsvenalqnfiapevlndsnqyfcekcne 341 ************.....9****************************************************************************** PP ......xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................... RF UCH 141 ......klkikrlPevLiihlkRfsynre..vkeKlntevefpeeldlseylaeeekektkekkk............................... 197 lk+ ++P L+++lkRf ++ + Kln++++fpe+l l+++++ee +e +++ + FUN_001019-T2 342 kcdahkGLKFISFPYLLTLQLKRFAFDYAtlHRVKLNDRMTFPEYLYLKDFVSEEHEETDADEDSsvkgdsqsstetdsgvsegcsdngmsteeed 437 **************************9888899*******************99998877766669****************************** PP ......................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............. RF UCH 198 ......................................YeLvavvvHsGslssGHYiayikaeeknkWvkfdDekvsevdee.............. 241 YeL+++++HsGs+++GHY+ayik+ e n+W++f+D++v++v ++ FUN_001019-T2 438 fdnarggadpvglasenleeseemltngitdnmkgpycYELFSIMIHSGSATGGHYYAYIKSFETNQWYCFNDQSVTRVYDDdiertyggvessrh 533 *******************************************************************************99866666666655555 PP ..xxxxx.....xxxxxxxx RF UCH 242 ..kevls.....esayiLfY 254 + s ++ay+L+Y FUN_001019-T2 534 yyS---SvytssTNAYMLMY 550 551...0555669******9 PP >> Ubiquitin_USP47_N Ubiquitin carboxyl-terminal hydrolase 47, ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.4 0.0 6.2e-34 1.7e-30 1 97 [. 21 117 .. 21 120 .. 0.97 2 ? -3.3 0.0 4.4 1.3e+04 18 44 .. 209 235 .. 205 238 .. 0.81 3 ! 5.5 0.0 0.0082 23 28 81 .. 729 780 .. 717 785 .. 0.90 Alignments for each domain: == domain 1 score: 105.4 bits; conditional E-value: 6.2e-34 Ubiquitin_USP47_N 1 prvlcIvrDmtnaktvnekltlnlpasttvkklfeeVakkfgYepdsfeLvlqrvkngdevelneeeektLeevgfveggkrnfLiltdkdg 92 p+vlcI++D t+++++n+k+t+nlpast+v++l+++ ak+++Y++dsf Lv+++ ++++e+ ln ++ktL+evg+v++gk+n + ++dkdg FUN_001019-T2 21 PTVLCIIKDETTSDWKNSKHTINLPASTPVQELITHAAKEAKYVEDSFLLVWSKPQGNEEILLNAFKDKTLQEVGLVSNGKKNSFLIKDKDG 112 68****************************************************99************************************ PP Ubiquitin_USP47_N 93 eqpkr 97 qp + FUN_001019-T2 113 VQPTK 117 **987 PP == domain 2 score: -3.3 bits; conditional E-value: 4.4 Ubiquitin_USP47_N 18 ekltlnlpasttvkklfeeVakkfgYe 44 +kl l l+as+ +++V k+fg + FUN_001019-T2 209 QKLFLLLQASSKRAVETTDVTKSFGWD 235 788899999999888889999998876 PP == domain 3 score: 5.5 bits; conditional E-value: 0.0082 Ubiquitin_USP47_N 28 ttvkklfeeVakkfgYepdsfeLvlqrvkngdevelneeeektLeevgfveggk 81 +t+k+l++ + ++f +++ +vl+ +e++l + ++k+L+e+gf+ ++k FUN_001019-T2 729 STAKDLHTLIHERFDLPLETLRVVLEG--SYNELKLLDRSDKSLKELGFFRSNK 780 789999999999999999********9..89999***************87765 PP >> UCH_1 Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.1 0.9 1.7e-24 5e-21 1 317 [] 160 513 .. 160 513 .. 0.80 2 ? -1.5 0.1 0.73 2.1e+03 127 205 .. 892 969 .. 820 1039 .. 0.72 Alignments for each domain: == domain 1 score: 76.1 bits; conditional E-value: 1.7e-24 UCH_1 1 sGLEthiansYtNslLQllrfipplrnlalshlat..eckkencLlcElgflfdmlekakgkncqasNFlkalssipeasalglleeeeeskkkas 94 +GL ++ ++Y+NslLQ+l+ +p++rn + + t e++ +++ ++l+ lf l+ ++++ ++++ k+++ + ++a + FUN_001019-T2 160 VGLVNQAMTCYLNSLLQTLFMTPEFRNAIYRWEFTgsEDEAGKSIPYQLQKLFLLLQASSKRAVETTDVTKSFGWDS-SEAWQ------------- 241 6999**********************9998765552277777*************************9999998666.22222............. PP UCH_1 95 lssliqsfnrflleqlsseekstkknsseaeseleqllgikaettirclsCgsesekesstlvldliypkkssnekkkknltfssilkssler... 187 ++ +q++ r++ + l+s++k+t + ++ +++l++ k++ ++c++Cg+es ++ + l + l ++ + ++ ++++ l++++ FUN_001019-T2 242 -QHDVQELCRVMFDALESKFKNTVQ-----DDLINKLYQGKLKDYVKCQQCGYESARTDTYLDIPLAI-RPFGSL--TALGSVENALQNFIAPevl 328 .344899************999875.....899*******************************9966.333222..3446888888888888666 PP UCH_1 188 ekttkawCekCkkyqtlesrrtvknlPpvLslnaaltseeelelWkd................................................. 234 +++++ +CekC+++ ++ + + P +L+l ++ + l + FUN_001019-T2 329 NDSNQYFCEKCNEKCDAHKGLKFISFPYLLTLQLKRFAFDYATLHRVklndrmtfpeylylkdfvseeheetdadedssvkgdsqsstetdsgvse 424 68899*********999999999************9844423333336677888888999988888888888888888888888887777766665 PP UCH_1 235 ....knwLpkeigltldkdkl..........................dlklklqeekekeeeeivvYeLvgvVveikdskekkshLvslvkvaese 300 + ++++ l+++ +++ ++ + YeL ++ ++ + s + +h+++++k e+ FUN_001019-T2 425 gcsdN---------------GmsteeedfdnarggadpvglasenleESEEMLTNGITDNMKGPYCYELFSIMIHSG-SAT-GGHYYAYIKSFET- 502 55541...............02333333355555557778888877778888888889999****************.654.9********8555. PP UCH_1 301 aeaekesqWylFNDflV 317 +qWy FND +V FUN_001019-T2 503 ------NQWYCFNDQSV 513 ......8*******877 PP == domain 2 score: -1.5 bits; conditional E-value: 0.73 UCH_1 127 eleqllgikaettirclsCgsesekesstlvldliypkkssnekkkknltfssilkssler....ekttkawCekCkkyqtle 205 +ql++++ ++r + ++ ++ e+ + ++ l++ +ek++ ++ f i+++ + e + +Ce+C + +le FUN_001019-T2 892 LSDQLTSFNDDAKVRVKYSRAPKKGEHQLKIFMLNA-----TEKEPVKYLFDWIVSDGMTVkqckELLHPEICERCDTDIPLE 969 345666666666666666666666666666665522.....344566677777777777654444667788888887766655 PP >> Ubiquitin_2 Ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.9 0.1 0.00012 0.34 14 66 .. 843 896 .. 836 908 .. 0.67 2 ? -4.1 0.0 9 2.6e+04 66 77 .. 936 947 .. 933 954 .. 0.70 3 ? 5.4 0.0 0.013 36 22 46 .. 1043 1067 .. 1039 1079 .. 0.88 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00012 Ubiquitin_2 14 vsserr..fsksltieelKekLelitGtspasmrLel.y.dkddnkvaklddddklL 66 + se+ ++k +t+++lKe L+ +G+sp++ r++ y ++++ ++ kl+d +L FUN_001019-T2 843 KTSEKLypIDKRITLGNLKEILQSEVGCSPEYFRVYRvYsSSQEIEYNKLSD---QL 896 566654115899***********************98344444444444443...34 PP == domain 2 score: -4.1 bits; conditional E-value: 9 Ubiquitin_2 66 LgsYgvedgmri 77 L ++ v+dgm++ FUN_001019-T2 936 LFDWIVSDGMTV 947 667777787776 PP == domain 3 score: 5.4 bits; conditional E-value: 0.013 Ubiquitin_2 22 ksltieelKekLelitGtspasmrL 46 k+ t+e+lKek+ + G+ ++ +L FUN_001019-T2 1043 KESTVEALKEKMSELSGIAVEDLEL 1067 678****************998776 PP >> ubiquitin Ubiquitin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.55 1.6e+03 6 39 .. 35 68 .. 31 73 .. 0.81 2 ? -3.0 0.1 3.3 9.3e+03 42 61 .. 272 290 .. 262 293 .. 0.83 3 ? 3.1 0.0 0.04 1.1e+02 18 45 .. 728 755 .. 721 783 .. 0.80 4 ? 0.9 0.0 0.19 5.5e+02 9 41 .. 845 877 .. 840 888 .. 0.84 5 ? -2.1 0.0 1.6 4.6e+03 18 31 .. 944 957 .. 940 973 .. 0.72 6 ? 6.5 0.0 0.0035 9.9 16 41 .. 1042 1067 .. 1040 1068 .. 0.88 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.55 ubiquitin 6 ldgkkitlevdesdtvlelKekieekegipaeqq 39 ++++k+t+ ++ s+ v+el + +++ ++ +++ FUN_001019-T2 35 WKNSKHTINLPASTPVQELITHAAKEAKYVEDSF 68 6889**************9888888877766665 PP == domain 2 score: -3.0 bits; conditional E-value: 3.3 ubiquitin 42 iysGkvLeddqtleeygikd 61 +y+Gk+ +d + +++g ++ FUN_001019-T2 272 LYQGKL-KDYVKCQQCGYES 290 699998.9999999998765 PP == domain 3 score: 3.1 bits; conditional E-value: 0.04 ubiquitin 18 sdtvlelKekieekegipaeqqrLiysG 45 ++t ++l+ i+e++++p e +r++++G FUN_001019-T2 728 NSTAKDLHTLIHERFDLPLETLRVVLEG 755 78999*********************99 PP == domain 4 score: 0.9 bits; conditional E-value: 0.19 ubiquitin 9 kkitlevdesdtvlelKekieekegipaeqqrL 41 ++ + +d+ t+ +lKe ++++ g +e +r+ FUN_001019-T2 845 SEKLYPIDKRITLGNLKEILQSEVGCSPEYFRV 877 55556788999**************99998886 PP == domain 5 score: -2.1 bits; conditional E-value: 1.6 ubiquitin 18 sdtvlelKekieek 31 tv+++Ke ++ + FUN_001019-T2 944 GMTVKQCKELLHPE 957 56999999998865 PP == domain 6 score: 6.5 bits; conditional E-value: 0.0035 ubiquitin 16 desdtvlelKekieekegipaeqqrL 41 +++tv+ lKek +e gi++e + L FUN_001019-T2 1042 LKESTVEALKEKMSELSGIAVEDLEL 1067 5789****************998765 PP >> tRNA-synt_1_2 Leucyl-tRNA synthetase, editing domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 4.2e-05 0.12 25 98 .. 538 611 .. 528 614 .. 0.84 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 4.2e-05 tRNA-synt_1_2 25 vfttrpdtlyGvtyvalapehplv.eklaekkeevaafieevkkekeaereleekekeGvatglkaihPltgekv 98 v+t+ + y y +ape + +l + +++a++i+++k+++e+er+ +e++++ + +++ hPlt++++ FUN_001019-T2 538 VYTSSTNA-YMLMYRKVAPERNAKfMELGDVPKHIAELIHKLKNHEEMERRRKEMDRSMCKIKIFCEHPLTKKRM 611 77776665.447788899987764156688999**************************************9987 PP >> DUF8118 Domain of unknown function (DUF8118) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.2 7.2e-05 0.2 18 32 .. 278 292 .. 273 298 .. 0.80 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.2e-05 DUF8118 18 arYvRCedCgrEvLt 32 ++Yv C++Cg E+ + FUN_001019-T2 278 KDYVKCQQCGYESAR 292 78**********964 PP >> OTU1_UBXL OTU1, UBXL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.026 74 9 32 .. 37 60 .. 35 67 .. 0.85 2 ? -2.0 0.0 2.8 7.9e+03 20 41 .. 729 750 .. 728 751 .. 0.86 3 ? -2.7 0.0 4.7 1.3e+04 17 37 .. 852 872 .. 850 876 .. 0.82 4 ? 3.8 0.1 0.043 1.2e+02 19 39 .. 1044 1064 .. 1030 1070 .. 0.88 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.026 OTU1_UBXL 9 sgqstitLdddatvgdLleeisek 32 + +ti+L+ ++ v++L+++ +++ FUN_001019-T2 37 NSKHTINLPASTPVQELITHAAKE 60 5679**************998765 PP == domain 2 score: -2.0 bits; conditional E-value: 2.8 OTU1_UBXL 20 atvgdLleeisektgipsfdik 41 +t +dL + i e ++p ++++ FUN_001019-T2 729 STAKDLHTLIHERFDLPLETLR 750 7999********9999988776 PP == domain 3 score: -2.7 bits; conditional E-value: 4.7 OTU1_UBXL 17 dddatvgdLleeisektgips 37 d t+g L+e ++++ g ++ FUN_001019-T2 852 DKRITLGNLKEILQSEVGCSP 872 66789******9999988765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.043 OTU1_UBXL 19 datvgdLleeisektgipsfd 39 ++tv+ L+e+ se +gi+++d FUN_001019-T2 1044 ESTVEALKEKMSELSGIAVED 1064 79***************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1138 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1120 (0.0438442); expected 510.9 (0.02) Passed bias filter: 669 (0.0261891); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.47u 0.39s 00:00:00.86 Elapsed: 00:00:00.43 # Mc/sec: 10654.26 // Query: FUN_001020-T1 [L=216] Description: FUN_001020 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-59 199.9 0.0 5.5e-59 199.6 0.0 1.0 1 Peptidase_C78 Peptidase family C78 ------ inclusion threshold ------ 0.65 9.9 1.9 1.1 9.1 0.8 1.8 2 Peptidase_C54 Peptidase C54 catalytic domain Domain annotation for each model (and alignments): >> Peptidase_C78 Peptidase family C78 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 199.6 0.0 4.3e-63 5.5e-59 4 200 .] 19 206 .. 17 206 .. 0.97 Alignments for each domain: == domain 1 score: 199.6 bits; conditional E-value: 4.3e-63 Peptidase_C78 4 slvlgsysyyhYlqdklkdkGwgCgYRnlQmllSwllenkysskeelkevptikeiQelleeawdkgadsqglvgsrkwIGttEvsavltsllgve 99 +v+g+y +yhY++d+++d+GwgCgYR+lQ+++Sw+++ +k+ +++vp++++iQ++l+e++dk+ + +vgsr+wIG++E+++++++++gv FUN_001020-T1 19 AIVRGRYLFYHYNVDGFDDRGWGCGYRTLQTICSWVCHALRDKKQ-VSKVPSLRQIQQTLVEVGDKPNS---FVGSREWIGSVEACLCVDQIFGVC 110 6899*********************************99887777.889********************...************************ PP Peptidase_C78 100 ckildvksgseleahaelleevaeyFektsgtpiylqhqghvlsrtilGvevskegelklLvlDPhytgaekslklvkkkgavswrkgakflkkkk 195 +ki++v++gs++ ++++ ++ e+F+ + g+p++++ +++++++ +lGv+ sk+g+ ++L++DPh++g+++ + l++++g+v+w+ ++ +k+++ FUN_001020-T1 111 SKIIHVNDGSHI--DKDVTVNLLEHFK-HFGSPVMIGGDADAAAKSLLGVCESKSGS-YFLIADPHFHGHAD-RLLLQSNGWVQWKHLEDVFKRES 201 ************..899999*******.***************************98.9************9.9999******************* PP Peptidase_C78 196 fynlv 200 fyn++ FUN_001020-T1 202 FYNFC 206 ***99 PP >> Peptidase_C54 Peptidase C54 catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.8 8.9e-05 1.1 30 48 .. 36 54 .. 24 86 .. 0.76 2 ? -1.7 0.0 0.17 2.2e+03 206 225 .. 153 176 .. 114 207 .. 0.65 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 8.9e-05 Peptidase_C54 30 sDtGWGCmlRsgQmllaqa 48 D GWGC R+ Q + + + FUN_001020-T1 36 DDRGWGCGYRTLQTICSWV 54 59***********997654 PP == domain 2 score: -1.7 bits; conditional E-value: 0.17 Peptidase_C54 206 Yfvgv....qddellyLDPHtvqe 225 ++gv +++++l DPH + FUN_001020-T1 153 SLLGVceskSGSYFLIADPHFHGH 176 444442233456778889997655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (216 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 490 (0.0191818); expected 510.9 (0.02) Passed bias filter: 422 (0.0165199); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2142.63 // Query: FUN_001021-T1 [L=348] Description: FUN_001021 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-41 143.5 12.1 1.3e-41 143.3 12.1 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 8.1e-07 29.2 9.2 1.3e-06 28.6 9.2 1.3 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 6.7e-06 26.1 7.2 1.2e-05 25.3 7.2 1.4 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00013 21.8 5.8 0.00019 21.2 5.8 1.2 1 7TM_GPCR_Srd Serpentine type 7TM GPCR chemoreceptor Srd ------ inclusion threshold ------ 0.05 13.8 0.0 0.11 12.8 0.0 1.6 1 TMEM132_C TMEM132 C-terminal 0.1 12.6 11.6 0.064 13.3 7.2 2.3 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 143.3 12.1 3.1e-45 1.3e-41 26 260 .] 1 240 [. 1 240 [. 0.90 Alignments for each domain: == domain 1 score: 143.3 bits; conditional E-value: 3.1e-45 xxxxxxxxxxxxxxxxx.xxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 26 LavaDllvlllvlpfal.vyallegdwvf....gevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkrralvlilvvWvlalll 116 +a+aDll++++++ +l + ++ + w + g+ lCkl+++ ++v++t+s+l+l+ai++DR+ aI +plk+ + t r+a+++i W+ ++++ FUN_001021-T1 1 MALADLLTTVFNMLPTLyWIFSGLDAWAVggwlGQTLCKLLNFAQSVSVTVSVLSLCAIAFDRFFAISRPLKR--VITFRVAKCIITSSWLSSITI 94 699******9776544413333336777655558999***********************************9..9******************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxx RF 7tm_1 117 slppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks...kkkksarkerkalktllv 207 + p+l++ +t+ + ++ +C+ ++ ++ t+ + yt+ l+vl + lpl +i+++y+ i+ +l+++++ ++ +++ +++++rk+lk+l++ FUN_001021-T1 95 AGPQLYVLTTTGK---QGLAQCVENWVPpfNQATAARDYTIALFVLLYALPLAIIAFLYTVIMFKLWRRRTPGQEltlNQENMEKTNRKVLKMLVT 187 ******9877655...89*******988667777***************************************998887777778888******** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 208 vvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 vv+vf+l wlP+ + ++++ ++ + l+ + l+tl+++++ns++NP iY FUN_001021-T1 188 VVIVFALSWLPLYVRMFVMFAESDRFVCGLPYDMDLLTLFFGHANSAINPYIY 240 *********************99999999999999****************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 9.2 2.9e-10 1.3e-06 56 256 .. 33 254 .. 6 255 .. 0.64 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 2.9e-10 7TM_GPCR_Srsx 56 lkreeCFlliivyvfgltaqsvllLvigiDlliavkfPirYrllskek.........YllillifpvlyssiilvlgflqrddetiivCa....pp 138 l ++ C ll++ ++++t++ + l +i++D+++a++ P++ r ++ + +i+++ p ly ++++ ++ + C pp FUN_001021-T1 33 LGQTLCKLLNFAQSVSVTVSVLSLCAIAFDRFFAISRPLK-RVITFRVakciitsswLSSITIAGPQLYVLTTT-------GKQGLAQCVenwvPP 120 568889999999********999***************87.333333111111111122333333444444444.......344455553222255 PP 7TM_GPCR_Srsx 139 lalagkaseiftlssliinv....ivllvylvliiilkkkkek............kkssskkvlkslkvtvvififgWftstilntvllaltesee 218 + a+ a+++ + ++++ i+ ++y v++++ + + +++ +kvlk l ++v++f ++W+ + v++a + ++ FUN_001021-T1 121 FNQATAARDYTIALFVLLYAlplaIIAFLYTVIMFK--LWRRRtpgqeltlnqenMEKTNRKVLKMLVTVVIVFALSWLPLYVRMFVMFAES-DRF 213 555555555555555555541100555555555555..33333446666666665888999*****************98776666655444.444 PP 7TM_GPCR_Srsx 219 vekl...iqayagilvllsfsqnffVtywrsseYrkafrel 256 v l + + + ++ +++ n +++++ +++Yrk f+++ FUN_001021-T1 214 VCGLpydMDLLTLFFGHANSAINPYIYVIFNENYRKGFKTV 254 3333222556677888999*******************986 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 7.2 2.8e-09 1.2e-05 39 317 .. 2 256 .. 1 258 [. 0.78 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 2.8e-09 7TM_GPCR_Srw 39 aicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlmAliRtlvvknplsnkiqklskpkfglliilivlll 134 a++D+lt+++++ + ++i++ + + +l l +l++ + vs +s+ ++A+ R++ + pl++ ++ +++ +ii+ l FUN_001021-T1 2 ALADLLTTVFNMLPTL-YWIFS--GLDAWAVGGWLGQTLCKLLNFAQSVSVTVSVLSLCAIAFDRFFAISRPLKRV----ITFRVAKCIITSSWLS 90 6677777777776666.55555..6777777666666666679***************************888775....579************* PP 7TM_GPCR_Srw 135 sllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifllidgilskiipsillpiltilLiieLrkakksrkkls 230 s+ i +++ + + ++ + C en v +++ a d ++ +f+l + +p ++ +l ++ +++L++ + ++l+ FUN_001021-T1 91 SITIAGPQLYVLTTTGKQGLAQ----CV---EN-----WVPPFNQATAARD-YTIALFVL-----LYALPLAIIAFLYTVIMFKLWRRRTPGQELT 168 *********9999998887766....*7...43.....4444444433333.23334444.....4567777777777777889999888888888 PP 7TM_GPCR_Srw 231 ..kskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifsllltinsisHflicllmSsqYRktvkklfg 317 ++++++ ++k k+ + + i+f ++ lpl + ++v ++ +++ + + ++++ + ++ +ns++ i++++ +YRk +k +++ FUN_001021-T1 169 lnQENMEKTNRKVLKMLVTVVIVFALSWLPLYVRMFV-MFAESDRFVCGLPYDMDLLTLFFGHANSAINPYIYVIFNENYRKGFKTVLS 256 6455577788899999999999********9999999.556777789999999*****************************9999876 PP >> 7TM_GPCR_Srd Serpentine type 7TM GPCR chemoreceptor Srd # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 5.8 4.4e-08 0.00019 76 291 .. 32 252 .. 27 253 .. 0.82 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 4.4e-08 7TM_GPCR_Srd 76 yfgptvCyvlysllqhfllhsllsllltfyyRyyilkk.....vkpkakklillllllyipslsqlivillsktdaleveaetkeehpnynleeys 166 ++g+t+C +l + ++++s+lsl + R+ ++++ ++++ k+i++ ++l+ + ++ +++l+ t ++ + + ++++p +n + FUN_001021-T1 32 WLGQTLCKLLNFAQSVSVTVSVLSLCAIAFDRFFAISRplkrvITFRVAKCIITSSWLSSITIAGPQLYVLTTTGKQGLAQCVENWVPPFNQA--T 125 789999999999999999999999999999999998652111134577778888888888888888899999999999999999999999764..3 PP 7TM_GPCR_Srd 167 vtGfsdlkslpaliaililtipvvpipiiililrkkilkl.lksnssnmssetkaqhkqLikgLtiQallPlifyiPivtlyllsqltgtelli.l 260 ++ +++l+a+ + +i++++ +i+ ++r+++ + l+ n++nm ++ ++ k+L+ +++ al l y+ +++++ s + l++ + FUN_001021-T1 126 AARDYTIALFVLLYALPLAIIAFLYTVIMFKLWRRRTPGQeLTLNQENMEKTNRKVLKMLVTVVIVFALSWLPLYVRMFVMFAESDRFVCGLPYdM 221 333445666777777777777777778888899999976515559************************999999999**************9966 PP 7TM_GPCR_Srd 261 eylifvllalpplldPlitlyfvtPYRkail 291 + l++++++ ++P+i+++f YRk ++ FUN_001021-T1 222 DLLTLFFGHANSAINPYIYVIFNENYRKGFK 252 88999999*******************9876 PP >> TMEM132_C TMEM132 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 2.5e-05 0.11 26 64 .. 125 166 .. 106 182 .. 0.77 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2.5e-05 TMEM132_C 26 raltdLEiGmYallgvfClailvflincvvfalkyrk...kk 64 a d i++++ll + lai++fl ++f+l r+ ++ FUN_001021-T1 125 TAARDYTIALFVLLYALPLAIIAFLYTVIMFKLWRRRtpgQE 166 55567789***********************99888844433 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 7.2 1.5e-05 0.064 70 207 .. 41 182 .. 9 190 .. 0.70 2 ? 1.8 0.4 0.051 2.2e+02 104 154 .. 180 234 .. 173 283 .. 0.71 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.5e-05 7TM_GPCR_Srx 70 iglialglYeisplsqllialNRfcavffplkyekifsiknTkiiiviiwivslifit....vlylpegCkllynpetltwsfeeteccktiswyl 161 + ++ + +s ls + ia++Rf+a+ pl +++ +++ +k+ii+ +w+ s+++ vl + l e ++ f++ + + ++ l FUN_001021-T1 41 LNFAQSVSVTVSVLSLCAIAFDRFFAISRPL--KRVITFRVAKCIITSSWLSSITIAGpqlyVLTTTGKQGLAQCVENWVPPFNQATAARDYTIAL 134 5666677778999******************..568999999**********99953355324444444555555666666666666666666666 PP 7TM_GPCR_Srx 162 dfllililviitlvlnlltaiklilskkksks..tsseeskrrrkrei 207 +ll+++ ++i+++l +++++kl +++ ++ ++e++++ +++ + FUN_001021-T1 135 FVLLYALPLAIIAFLYTVIMFKLWRRRTPGQEltLNQENMEKTNRKVL 182 455666667777888888888888555555441133333344444444 PP == domain 2 score: 1.8 bits; conditional E-value: 0.051 7TM_GPCR_Srx 104 kifsiknTkiiiviiwivslif.itvlylpeg...Ckllynpetltwsfeetecc 154 k+ ++ T++i++++ + l++ ++v++ ++ C l y+ + lt++f + + FUN_001021-T1 180 KVLKMLVTVVIVFALSWLPLYVrMFVMFAESDrfvCGLPYDMDLLTLFFGHANSA 234 5566667777776655555554355555443344499****99999999654433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (348 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1021 (0.0399687); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3410.71 // Query: FUN_001022-T1 [L=777] Description: FUN_001022 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-165 535.9 325.7 2.8e-11 43.9 10.5 17.1 17 EGF_3 EGF domain 3e-143 466.4 303.7 3.1e-10 40.6 9.5 17.1 17 EGF_CA Calcium-binding EGF domain 5.1e-100 327.3 164.1 4.9e-08 33.2 2.2 17.8 17 cEGF Complement Clr-like EGF-like 7.7e-37 125.5 251.6 0.00048 20.6 5.6 17.3 17 EGF_MSP1_1 MSP1 EGF domain 1 5.2e-28 97.4 267.4 0.0023 18.7 5.6 18.4 17 EGF EGF-like domain 2.4e-15 56.8 250.1 0.0017 19.2 5.7 25.0 26 hEGF Human growth factor-like EGF 3.3e-10 40.4 277.6 0.049 14.3 7.4 17.6 17 FXa_inhibition Coagulation Factor Xa inhibitory site 2.2e-06 28.5 250.5 0.069 14.1 6.5 17.3 17 ADGRF3_N ADGRF3-like, N-terminal domain 0.0015 19.0 6.5 0.0015 19.0 6.5 18.5 17 Plasmod_Pvs28 Pvs28 EGF domain ------ inclusion threshold ------ 0.043 13.9 253.1 2.6e+04 -24.3 132.5 4.7 0 EGF_TEN Teneurin EGF domain 0.21 10.8 0.3 14 4.9 0.0 3.2 3 UxuA D-mannonate dehydratase (UxuA) 3.7 8.8 218.4 0.49 11.6 6.3 17.0 17 GPR158_179_EC GPR158/179 extracellular domain Domain annotation for each model (and alignments): >> EGF_3 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 8.0 8.8e-10 1.9e-06 8 36 .] 63 92 .. 60 92 .. 0.96 2 ! 39.8 9.9 2.7e-13 5.7e-10 3 36 .] 101 134 .. 98 134 .. 0.94 3 ! 39.4 10.6 3.3e-13 7e-10 1 36 [] 140 175 .. 140 175 .. 0.99 4 ! 40.5 12.6 1.6e-13 3.4e-10 1 36 [] 181 216 .. 181 216 .. 0.99 5 ! 38.0 9.4 9.2e-13 2e-09 1 36 [] 222 257 .. 222 257 .. 0.99 6 ! 37.4 13.0 1.4e-12 3.1e-09 1 36 [] 263 298 .. 263 298 .. 0.99 7 ! 40.0 11.5 2.2e-13 4.7e-10 1 36 [] 304 339 .. 304 339 .. 0.99 8 ! 36.4 11.4 3e-12 6.4e-09 3 36 .] 346 379 .. 345 379 .. 0.96 9 ! 42.1 12.0 4.8e-14 1e-10 1 36 [] 385 420 .. 385 420 .. 0.99 10 ! 43.2 12.2 2.2e-14 4.7e-11 1 36 [] 426 461 .. 426 461 .. 0.99 11 ! 43.1 11.1 2.4e-14 5.2e-11 1 36 [] 467 502 .. 467 502 .. 0.99 12 ! 43.9 10.5 1.3e-14 2.8e-11 1 36 [] 508 543 .. 508 543 .. 0.99 13 ! 35.0 8.1 8.3e-12 1.8e-08 1 36 [] 549 584 .. 549 584 .. 0.98 14 ! 34.6 14.4 1.1e-11 2.3e-08 1 36 [] 590 625 .. 590 625 .. 1.00 15 ! 26.8 12.5 3e-09 6.5e-06 1 36 [] 631 666 .. 631 666 .. 0.99 16 ! 37.5 10.7 1.3e-12 2.8e-09 3 36 .] 673 706 .. 672 706 .. 0.94 17 ! 33.9 19.9 1.8e-11 3.9e-08 1 36 [] 712 747 .. 712 747 .. 0.99 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 8.8e-10 EGF_3 8 ChanAtCtnteg.sfkCtCkagytGdGvtC 36 C++nA+C+ +++ ++C+Ck+g++G+G +C FUN_001022-T1 63 CDVNAICKAIGKnYHSCQCKNGFQGNGSVC 92 ************999*************** PP == domain 2 score: 39.8 bits; conditional E-value: 2.7e-13 EGF_3 3 knnggChanAtCtntegsfkCtCkagytGdGvtC 36 ++ +gC+ +A+C nt+gs++C C++g++GdG+tC FUN_001022-T1 101 EELNGCSRKADCVNTNGSYNCVCHRGFQGDGWTC 134 5678****************************** PP == domain 3 score: 39.4 bits; conditional E-value: 3.3e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C++++++C+ +A+C+n gs+ CtC++g++G G+ C FUN_001022-T1 140 CKEKTHNCSLHADCQNSIGSYDCTCHEGFEGVGWAC 175 ***********************************9 PP == domain 4 score: 40.5 bits; conditional E-value: 1.6e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+++A+Ctn gs+ CtC++g++GdG++C FUN_001022-T1 181 CKRGIHNCSVHADCTNSIGSYDCTCQQGHQGDGWKC 216 9*********************************** PP == domain 5 score: 38.0 bits; conditional E-value: 9.2e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C++ A+C n gs+kC C++g++GdG+tC FUN_001022-T1 222 CRRGIHNCSVYADCLNSIGSHKCVCHHGFQGDGWTC 257 99********************************** PP == domain 6 score: 37.4 bits; conditional E-value: 1.4e-12 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+++ ++C+ +A+Ctn gs+ CtC++g++GdG++C FUN_001022-T1 263 CKEKIHNCSFHADCTNSIGSYDCTCHQGHQGDGWKC 298 ************************************ PP == domain 7 score: 40.0 bits; conditional E-value: 2.2e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C++ A+Ctn gs+kC C++g++GdG+tC FUN_001022-T1 304 CKRGIHNCSVYADCTNSIGSHKCVCHHGFQGDGWTC 339 9*********************************** PP == domain 8 score: 36.4 bits; conditional E-value: 3e-12 EGF_3 3 knnggChanAtCtntegsfkCtCkagytGdGvtC 36 k++++C++ A+C+n gs+ CtC++g++GdG+ C FUN_001022-T1 346 KETHNCSVYADCKNSIGSYDCTCHEGFEGDGWAC 379 4789*****************************9 PP == domain 9 score: 42.1 bits; conditional E-value: 4.8e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ ++C++ A+Ctn+ gs++CtC++g++GdG+tC FUN_001022-T1 385 CKRSMHNCSVYADCTNNIGSYNCTCHRGFQGDGWTC 420 999********************************* PP == domain 10 score: 43.2 bits; conditional E-value: 2.2e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C++++++C+++A+C+n gs++CtC++g++GdG+ C FUN_001022-T1 426 CKEKTHKCSVHADCKNSIGSYNCTCHEGFEGDGWAC 461 ***********************************9 PP == domain 11 score: 43.1 bits; conditional E-value: 2.4e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+++A+C n gs+ CtC++g++GdG++C FUN_001022-T1 467 CKRGIHNCSVHADCINSIGSYDCTCHQGFQGDGFVC 502 9*********************************** PP == domain 12 score: 43.9 bits; conditional E-value: 1.3e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+++A+Ctn gs++CtC++g++GdG+ C FUN_001022-T1 508 CKREIHNCSVHADCTNSIGSYRCTCHQGFKGDGWAC 543 9**********************************9 PP == domain 13 score: 35.0 bits; conditional E-value: 8.3e-12 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+ +A Ctn+ g f+C+C +g++G+G+ C FUN_001022-T1 549 CKMRVDNCSRHAFCTNNVGAFNCKCLEGFEGNGWLC 584 99999*****************************99 PP == domain 14 score: 34.6 bits; conditional E-value: 1.1e-11 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 Cs +++ C+ +A C+n +gs+ C+C gytGdG tC FUN_001022-T1 590 CSRGTHSCDTHASCRNKDGSHICICDGGYTGDGETC 625 ************************************ PP == domain 15 score: 26.8 bits; conditional E-value: 3e-09 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+++++ C+ n +C+nt+gs++C C +gy+ +G +C FUN_001022-T1 631 CQDGTHTCGLNSRCHNTQGSYRCPCVEGYSVNGGVC 666 *********************************999 PP == domain 16 score: 37.5 bits; conditional E-value: 1.3e-12 EGF_3 3 knnggChanAtCtntegsfkCtCkagytGdGvtC 36 +n Ch++A Ctnt+g+++C+C++g +GdG++C FUN_001022-T1 673 NNRRSCHPHASCTNTAGTYSCRCNPGLRGDGISC 706 46679***************************** PP == domain 17 score: 33.9 bits; conditional E-value: 1.8e-11 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+++ ++C++nA+Ctn+ gs++C Ck+g++GdG++C FUN_001022-T1 712 CTTGDHDCDKNAKCTNNWGSYHCCCKKGFHGDGKEC 747 ************************************ PP >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 7.6 0.11 2.4e+02 3 43 .] 55 92 .. 54 92 .. 0.78 2 ! 34.3 9.5 1.4e-11 2.9e-08 1 43 [] 94 134 .. 94 134 .. 0.92 3 ! 39.3 10.1 3.8e-13 8.2e-10 1 40 [. 136 172 .. 136 175 .. 0.91 4 ! 36.1 10.7 3.7e-12 8e-09 1 43 [] 177 216 .. 177 216 .. 0.93 5 ! 36.3 7.7 3.3e-12 7e-09 1 43 [] 218 257 .. 218 257 .. 0.93 6 ! 32.9 11.5 3.6e-11 7.6e-08 1 43 [] 259 298 .. 259 298 .. 0.93 7 ! 34.9 9.3 8.6e-12 1.8e-08 1 43 [] 300 339 .. 300 339 .. 0.93 8 ! 31.7 12.3 8.7e-11 1.9e-07 1 43 [] 341 379 .. 341 379 .. 0.91 9 ! 35.9 11.3 4.4e-12 9.4e-09 1 43 [] 381 420 .. 381 420 .. 0.93 10 ! 37.4 11.5 1.4e-12 3e-09 1 43 [] 422 461 .. 422 461 .. 0.92 11 ! 39.8 9.4 2.5e-13 5.4e-10 1 43 [] 463 502 .. 463 502 .. 0.95 12 ! 37.9 9.3 1e-12 2.2e-09 1 43 [] 504 543 .. 504 543 .. 0.92 13 ! 33.6 8.3 2.3e-11 4.9e-08 1 35 [. 545 578 .. 545 584 .. 0.93 14 ! 33.5 11.6 2.4e-11 5.1e-08 1 43 [] 586 625 .. 586 625 .. 0.96 15 ! 40.6 9.5 1.4e-13 3.1e-10 1 37 [. 627 662 .. 627 666 .. 0.91 16 ! 31.7 7.9 8.5e-11 1.8e-07 1 40 [. 668 703 .. 668 706 .. 0.88 17 ! 31.7 18.3 9e-11 1.9e-07 1 43 [] 708 747 .. 708 747 .. 0.96 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.11 EGF_CA 3 dECaegthnCpdentvCvNteGsf.eCvCeegyennedgkkC 43 d C + +C d n++C + +C+C++g++ +g+ C FUN_001022-T1 55 DDCWLKR-VC-DVNAICKAIGKNYhSCQCKNGFQ--GNGSVC 92 6677755.9*.7*****988777747********..666655 PP == domain 2 score: 34.3 bits; conditional E-value: 1.4e-11 EGF_CA 1 DvdECaegt.hnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D++EC +++ + C ++++ CvNt+Gs++CvC++g++ dg +C FUN_001022-T1 94 DLNECLSEElNGC-SRKADCVNTNGSYNCVCHRGFQ--GDGWTC 134 9******99899*.8********************9..666666 PP == domain 3 score: 39.3 bits; conditional E-value: 3.8e-13 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedg 40 DvdEC+e thnC + ++ C+N++Gs++C+C+eg+e +g FUN_001022-T1 136 DVDECKEKTHNC-SLHADCQNSIGSYDCTCHEGFE--GVG 172 9***********.8********************9..555 PP == domain 4 score: 36.1 bits; conditional E-value: 3.7e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ g hnC + ++ C+N++Gs++C+C++g + dg kC FUN_001022-T1 177 DVNECKRGIHNC-SVHADCTNSIGSYDCTCQQGHQ--GDGWKC 216 9***********.8*******************98..776666 PP == domain 5 score: 36.3 bits; conditional E-value: 3.3e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ g hnC + + C N++Gs +CvC++g++ dg +C FUN_001022-T1 218 DVNECRRGIHNC-SVYADCLNSIGSHKCVCHHGFQ--GDGWTC 257 9***********.8********************9..666666 PP == domain 6 score: 32.9 bits; conditional E-value: 3.6e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+e hnC + ++ C+N++Gs++C+C++g + dg kC FUN_001022-T1 259 DVNECKEKIHNC-SFHADCTNSIGSYDCTCHQGHQ--GDGWKC 298 9***********.8*******************98..776666 PP == domain 7 score: 34.9 bits; conditional E-value: 8.6e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ g hnC + + C+N++Gs +CvC++g++ dg +C FUN_001022-T1 300 DVNECKRGIHNC-SVYADCTNSIGSHKCVCHHGFQ--GDGWTC 339 9***********.8********************9..666666 PP == domain 8 score: 31.7 bits; conditional E-value: 8.7e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+e thnC + + C N++Gs++C+C+eg+e dg +C FUN_001022-T1 341 DVNECKE-THNC-SVYADCKNSIGSYDCTCHEGFE--GDGWAC 379 9****99.88**.8********************9..666555 PP == domain 9 score: 35.9 bits; conditional E-value: 4.4e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ hnC + + C+N++Gs++C+C++g++ dg +C FUN_001022-T1 381 DVNECKRSMHNC-SVYADCTNNIGSYNCTCHRGFQ--GDGWTC 420 9***********.8********************9..666666 PP == domain 10 score: 37.4 bits; conditional E-value: 1.4e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+e th+C + ++ C N++Gs++C+C+eg+e dg +C FUN_001022-T1 422 DVNECKEKTHKC-SVHADCKNSIGSYNCTCHEGFE--GDGWAC 461 9***********.8********************9..666555 PP == domain 11 score: 39.8 bits; conditional E-value: 2.5e-13 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ g hnC + ++ C+N++Gs++C+C++g++ dg+ C FUN_001022-T1 463 DVNECKRGIHNC-SVHADCINSIGSYDCTCHQGFQ--GDGFVC 502 9***********.8*********************..888777 PP == domain 12 score: 37.9 bits; conditional E-value: 1e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ + hnC + ++ C+N++Gs++C+C++g++ dg +C FUN_001022-T1 504 DVNECKREIHNC-SVHADCTNSIGSYRCTCHQGFK--GDGWAC 543 9***********.8********************9..666555 PP == domain 13 score: 33.6 bits; conditional E-value: 2.3e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegye 35 D+dEC+ +nC ++++ C+N++G f+C+C eg+e FUN_001022-T1 545 DIDECKMRVDNC-SRHAFCTNNVGAFNCKCLEGFE 578 9***********.8********************9 PP == domain 14 score: 33.5 bits; conditional E-value: 2.4e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC gth+C d +++C N++Gs C C+ gy+ dg++C FUN_001022-T1 586 DVNECSRGTHSC-DTHASCRNKDGSHICICDGGYT--GDGETC 625 9***********.7*********************..888888 PP == domain 15 score: 40.6 bits; conditional E-value: 1.4e-13 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyenn 37 D+dEC++gth C n+ C+Nt+Gs++C C egy++n FUN_001022-T1 627 DIDECQDGTHTC-GLNSRCHNTQGSYRCPCVEGYSVN 662 9***********.7********************944 PP == domain 16 score: 31.7 bits; conditional E-value: 8.5e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedg 40 D++EC++ + +C + +++C+Nt G+++C+C++g + dg FUN_001022-T1 668 DINECNNRR-SC-HPHASCTNTAGTYSCRCNPGLR--GDG 703 9******77.**.99*****************977..555 PP == domain 17 score: 31.7 bits; conditional E-value: 9e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D dEC++g h+C d+n++C+N+ Gs++C C++g++ dgk+C FUN_001022-T1 708 DYDECTTGDHDC-DKNAKCTNNWGSYHCCCKKGFH--GDGKEC 747 89**********.7*********************..999998 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.6 6.2e-06 0.013 3 24 .] 78 97 .. 77 97 .. 0.93 2 ! 32.0 2.9 5.4e-11 1.2e-07 1 24 [] 118 139 .. 118 139 .. 0.99 3 ! 22.0 1.6 7e-08 0.00015 1 24 [] 159 180 .. 159 180 .. 0.98 4 ! 26.2 3.4 3.5e-09 7.4e-06 1 24 [] 200 221 .. 200 221 .. 0.98 5 ! 30.3 0.9 1.8e-10 3.9e-07 1 24 [] 241 262 .. 241 262 .. 0.97 6 ! 28.0 3.2 9.2e-10 2e-06 1 24 [] 282 303 .. 282 303 .. 0.98 7 ! 30.3 0.9 1.8e-10 3.9e-07 1 24 [] 323 344 .. 323 344 .. 0.97 8 ! 28.8 2.7 5.4e-10 1.1e-06 1 24 [] 363 384 .. 363 384 .. 0.98 9 ! 30.8 2.7 1.3e-10 2.7e-07 1 24 [] 404 425 .. 404 425 .. 0.99 10 ! 30.4 1.8 1.7e-10 3.6e-07 1 24 [] 445 466 .. 445 466 .. 0.99 11 ! 29.4 4.0 3.4e-10 7.2e-07 1 24 [] 486 507 .. 486 507 .. 0.98 12 ! 33.2 2.2 2.3e-11 4.9e-08 1 24 [] 527 548 .. 527 548 .. 0.99 13 ! 21.8 0.1 8.4e-08 0.00018 2 24 .] 569 589 .. 568 589 .. 0.96 14 ! 18.1 6.3 1.2e-06 0.0025 1 24 [] 609 630 .. 609 630 .. 0.95 15 ! 17.7 3.0 1.6e-06 0.0035 1 24 [] 650 671 .. 650 671 .. 0.98 16 ! 13.9 4.3 2.4e-05 0.051 2 24 .] 691 711 .. 690 711 .. 0.95 17 ! 10.6 6.6 0.00027 0.57 1 20 [. 731 748 .. 731 749 .. 0.96 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 6.2e-06 cEGF 3 tCsCppGYtLagDGrtCvDIDE 24 C+C++G++ g+G C D +E FUN_001022-T1 78 SCQCKNGFQ--GNGSVCFDLNE 97 6********..9*****99998 PP == domain 2 score: 32.0 bits; conditional E-value: 5.4e-11 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C C++G++ gDG tC+D+DE FUN_001022-T1 118 SYNCVCHRGFQ--GDGWTCTDVDE 139 9**********..**********9 PP == domain 3 score: 22.0 bits; conditional E-value: 7e-08 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ g G C+D++E FUN_001022-T1 159 SYDCTCHEGFE--GVGWACTDVNE 180 9**********..99********9 PP == domain 4 score: 26.2 bits; conditional E-value: 3.5e-09 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C +G + gDG +C+D++E FUN_001022-T1 200 SYDCTCQQGHQ--GDGWKCTDVNE 221 9**********..**********9 PP == domain 5 score: 30.3 bits; conditional E-value: 1.8e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 S +C C+ G++ gDG tC+D++E FUN_001022-T1 241 SHKCVCHHGFQ--GDGWTCTDVNE 262 789********..**********9 PP == domain 6 score: 28.0 bits; conditional E-value: 9.2e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G + gDG +C+D++E FUN_001022-T1 282 SYDCTCHQGHQ--GDGWKCTDVNE 303 9**********..**********9 PP == domain 7 score: 30.3 bits; conditional E-value: 1.8e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 S +C C+ G++ gDG tC+D++E FUN_001022-T1 323 SHKCVCHHGFQ--GDGWTCTDVNE 344 789********..**********9 PP == domain 8 score: 28.8 bits; conditional E-value: 5.4e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ gDG C+D++E FUN_001022-T1 363 SYDCTCHEGFE--GDGWACKDVNE 384 9**********..**********9 PP == domain 9 score: 30.8 bits; conditional E-value: 1.3e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ gDG tC D++E FUN_001022-T1 404 SYNCTCHRGFQ--GDGWTCNDVNE 425 9**********..**********9 PP == domain 10 score: 30.4 bits; conditional E-value: 1.7e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ gDG C+D++E FUN_001022-T1 445 SYNCTCHEGFE--GDGWACKDVNE 466 9**********..**********9 PP == domain 11 score: 29.4 bits; conditional E-value: 3.4e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ gDG C+D++E FUN_001022-T1 486 SYDCTCHQGFQ--GDGFVCKDVNE 507 9**********..9*********9 PP == domain 12 score: 33.2 bits; conditional E-value: 2.3e-11 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY+C+C++G++ gDG C DIDE FUN_001022-T1 527 SYRCTCHQGFK--GDGWACSDIDE 548 9**********..**********9 PP == domain 13 score: 21.8 bits; conditional E-value: 8.4e-08 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 + C C +G++ g+G C+D++E FUN_001022-T1 569 FNCKCLEGFE--GNGWLCTDVNE 589 78********..9*********9 PP == domain 14 score: 18.1 bits; conditional E-value: 1.2e-06 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 S C C GYt gDG tC+DIDE FUN_001022-T1 609 SHICICDGGYT--GDGETCKDIDE 630 678********..9*********9 PP == domain 15 score: 17.7 bits; conditional E-value: 1.6e-06 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY+C C +GY+ +G C DI+E FUN_001022-T1 650 SYRCPCVEGYS--VNGGVCSDINE 671 9**********..9*********9 PP == domain 16 score: 13.9 bits; conditional E-value: 2.4e-05 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 Y C C+pG + gDG +C D DE FUN_001022-T1 691 YSCRCNPGLR--GDGISCSDYDE 711 9*********..9*******998 PP == domain 17 score: 10.6 bits; conditional E-value: 0.00027 cEGF 1 SYtCsCppGYtLagDGrtCv 20 SY+C C++G+ gDG+ C+ FUN_001022-T1 731 SYHCCCKKGFH--GDGKECK 748 9**********..9*****6 PP >> EGF_MSP1_1 MSP1 EGF domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 7.7 0.24 5e+02 4 36 .. 60 92 .. 56 93 .. 0.88 2 ! 13.5 7.8 3.5e-05 0.075 7 36 .. 106 134 .. 97 135 .. 0.89 3 ! 13.9 6.9 2.8e-05 0.059 5 36 .. 145 175 .. 139 176 .. 0.87 4 ! 14.7 6.6 1.5e-05 0.032 5 36 .. 186 216 .. 180 217 .. 0.90 5 ! 12.9 5.4 5.5e-05 0.12 2 36 .. 222 257 .. 221 258 .. 0.87 6 ! 13.9 6.9 2.8e-05 0.059 5 36 .. 268 298 .. 262 299 .. 0.89 7 ! 11.5 5.8 0.00015 0.32 5 36 .. 309 339 .. 303 340 .. 0.89 8 ! 8.1 8.4 0.0018 3.8 1 36 [. 344 379 .. 344 380 .. 0.90 9 ! 10.5 8.1 0.00031 0.65 5 36 .. 390 420 .. 384 421 .. 0.89 10 ! 10.7 8.3 0.00028 0.6 5 36 .. 431 461 .. 425 462 .. 0.87 11 ! 17.4 4.9 2.2e-06 0.0046 5 36 .. 472 502 .. 466 503 .. 0.87 12 ! 16.3 6.3 5e-06 0.011 5 36 .. 513 543 .. 507 544 .. 0.89 13 ! 10.1 7.8 0.00043 0.91 5 36 .. 554 584 .. 548 585 .. 0.87 14 ! 20.6 5.6 2.3e-07 0.00048 5 36 .. 595 625 .. 589 626 .. 0.90 15 ! 15.1 7.3 1.2e-05 0.025 2 36 .. 631 666 .. 630 667 .. 0.90 16 ! 19.4 7.0 5.1e-07 0.0011 1 36 [. 671 706 .. 671 707 .. 0.91 17 ! 19.4 13.0 5.2e-07 0.0011 3 36 .. 715 747 .. 711 748 .. 0.92 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.24 EGF_MSP1_1 4 kvkcPaNAkCvrhadgreECrCllgykkeggkC 36 k+ c+ NA C C C+ g+ +g+ C FUN_001022-T1 60 KRVCDVNAICKAIGKNYHSCQCKNGFQGNGSVC 92 789*******988867789***********999 PP == domain 2 score: 13.5 bits; conditional E-value: 3.5e-05 EGF_MSP1_1 7 cPaNAkCvrhadgreECrCllgykkeggkC 36 c A+Cv+ g++ C+C g+ +g +C FUN_001022-T1 106 CSRKADCVNTN-GSYNCVCHRGFQGDGWTC 134 8889*****99.***************999 PP == domain 3 score: 13.9 bits; conditional E-value: 2.8e-05 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g++ C C g+ +g C FUN_001022-T1 145 HNCSLHADCQNSI-GSYDCTCHEGFEGVGWAC 175 79***********.***********9999877 PP == domain 4 score: 14.7 bits; conditional E-value: 1.5e-05 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g++ C C g +g kC FUN_001022-T1 186 HNCSVHADCTNSI-GSYDCTCQQGHQGDGWKC 216 6899*********.****************** PP == domain 5 score: 12.9 bits; conditional E-value: 5.5e-05 EGF_MSP1_1 2 Cvk..vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C+ +c A+C ++ g+ C+C g+ +g +C FUN_001022-T1 222 CRRgiHNCSVYADCLNSI-GSHKCVCHHGFQGDGWTC 257 55545689999*******.***************999 PP == domain 6 score: 13.9 bits; conditional E-value: 2.8e-05 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g++ C C g +g kC FUN_001022-T1 268 HNCSFHADCTNSI-GSYDCTCHQGHQGDGWKC 298 69999********.****************** PP == domain 7 score: 11.5 bits; conditional E-value: 0.00015 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c A+C ++ g+ C+C g+ +g +C FUN_001022-T1 309 HNCSVYADCTNSI-GSHKCVCHHGFQGDGWTC 339 588899*******.***************999 PP == domain 8 score: 8.1 bits; conditional E-value: 0.0018 EGF_MSP1_1 1 eCvk.vkcPaNAkCvrhadgreECrCllgykkeggkC 36 eC + +c A+C ++ g++ C C g+ +g C FUN_001022-T1 344 ECKEtHNCSVYADCKNSI-GSYDCTCHEGFEGDGWAC 379 5877789***********.***********9999777 PP == domain 9 score: 10.5 bits; conditional E-value: 0.00031 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c A+C ++ g++ C C g+ +g +C FUN_001022-T1 390 HNCSVYADCTNNI-GSYNCTCHRGFQGDGWTC 420 688999*******.***************999 PP == domain 10 score: 10.7 bits; conditional E-value: 0.00028 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 kc +A+C ++ g++ C C g+ +g C FUN_001022-T1 431 HKCSVHADCKNSI-GSYNCTCHEGFEGDGWAC 461 69***********.***********9999777 PP == domain 11 score: 17.4 bits; conditional E-value: 2.2e-06 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C+++ g++ C C g+ +g C FUN_001022-T1 472 HNCSVHADCINSI-GSYDCTCHQGFQGDGFVC 502 6899*********.***********9998666 PP == domain 12 score: 16.3 bits; conditional E-value: 5e-06 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g++ C C g+k +g C FUN_001022-T1 513 HNCSVHADCTNSI-GSYRCTCHQGFKGDGWAC 543 6899*********.**************9888 PP == domain 13 score: 10.1 bits; conditional E-value: 0.00043 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g C+Cl g+ +g C FUN_001022-T1 554 DNCSRHAFCTNNV-GAFNCKCLEGFEGNGWLC 584 58***********.***********9988666 PP == domain 14 score: 20.6 bits; conditional E-value: 2.3e-07 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c+ +A C +++ g+ C+C gy +g++C FUN_001022-T1 595 HSCDTHASCRNKD-GSHICICDGGYTGDGETC 625 79*******9888.****************** PP == domain 15 score: 15.1 bits; conditional E-value: 1.2e-05 EGF_MSP1_1 2 Cvk..vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C + c N+ C + g++ C C gy+ +gg C FUN_001022-T1 631 CQDgtHTCGLNSRCHNTQ-GSYRCPCVEGYSVNGGVC 666 6665568***********.****************99 PP == domain 16 score: 19.4 bits; conditional E-value: 5.1e-07 EGF_MSP1_1 1 eCvk.vkcPaNAkCvrhadgreECrCllgykkeggkC 36 eC + ++c +A C + a g++ CrC++g +g C FUN_001022-T1 671 ECNNrRSCHPHASCTNTA-GTYSCRCNPGLRGDGISC 706 799999************.**********88888776 PP == domain 17 score: 19.4 bits; conditional E-value: 5.2e-07 EGF_MSP1_1 3 vkvkcPaNAkCvrhadgreECrCllgykkeggkC 36 ++ +c++NAkC ++ g++ C C+ g+ +g +C FUN_001022-T1 715 GDHDCDKNAKCTNNW-GSYHCCCKKGFHGDGKEC 747 4689***********.****************** PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 4.2 0.00041 0.87 6 31 .. 63 88 .. 57 89 .. 0.91 2 ! 9.0 7.6 0.0012 2.5 4 31 .. 104 130 .. 92 131 .. 0.87 3 ! 10.2 7.2 0.00047 1 3 30 .. 142 170 .. 140 172 .. 0.87 4 ! 8.7 8.7 0.0014 3 4 31 .. 186 212 .. 181 213 .. 0.89 5 ! 12.3 7.0 0.00011 0.23 4 31 .. 227 253 .. 222 254 .. 0.92 6 ? 4.5 9.0 0.029 63 4 31 .. 268 294 .. 263 295 .. 0.88 7 ! 10.3 8.1 0.00045 0.95 4 31 .. 309 335 .. 304 336 .. 0.90 8 ! 11.4 8.2 0.0002 0.43 1 31 [. 345 375 .. 345 376 .. 0.94 9 ! 10.4 8.4 0.00043 0.91 4 31 .. 390 416 .. 385 417 .. 0.90 10 ! 14.2 9.6 2.6e-05 0.056 1 31 [. 426 457 .. 420 458 .. 0.87 11 ! 13.8 7.7 3.6e-05 0.076 4 31 .. 472 498 .. 467 499 .. 0.91 12 ! 16.5 7.2 5e-06 0.011 4 31 .. 513 539 .. 508 540 .. 0.90 13 ! 18.7 5.6 1.1e-06 0.0023 4 31 .. 554 580 .. 549 581 .. 0.89 14 ! 13.2 9.4 5.6e-05 0.12 1 31 [. 590 621 .. 590 622 .. 0.94 15 ! 7.6 8.2 0.0031 6.6 1 29 [. 631 660 .. 625 660 .. 0.88 16 ! 15.2 9.6 1.3e-05 0.027 1 31 [. 672 702 .. 666 703 .. 0.87 17 ! 12.8 13.8 7.2e-05 0.15 1 31 [. 712 743 .. 712 744 .. 0.87 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00041 EGF 6 CsngGtCvdtprggytCiCpeGytGk 31 C+ +++C + + ++C+C++G+ G+ FUN_001022-T1 63 CDVNAICKAIGKNYHSCQCKNGFQGN 88 999********999**********97 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0012 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 n Cs + Cv+t g+y+C C G+ G+ FUN_001022-T1 104 NGCSRKADCVNTN-GSYNCVCHRGFQGD 130 45888888*****.************97 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00047 EGF 3 p..npCsngGtCvdtprggytCiCpeGytG 30 + ++Cs ++ C ++ g+y C+C eG+ G FUN_001022-T1 142 EktHNCSLHADCQNSI-GSYDCTCHEGFEG 170 54478***********.***********99 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0014 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs ++ C ++ g+y C+C++G G+ FUN_001022-T1 186 HNCSVHADCTNSI-GSYDCTCQQGHQGD 212 89***********.**********9997 PP == domain 5 score: 12.3 bits; conditional E-value: 0.00011 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs + C+++ g+++C C +G+ G+ FUN_001022-T1 227 HNCSVYADCLNSI-GSHKCVCHHGFQGD 253 89***********.************97 PP == domain 6 score: 4.5 bits; conditional E-value: 0.029 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs ++ C ++ g+y C+C +G G+ FUN_001022-T1 268 HNCSFHADCTNSI-GSYDCTCHQGHQGD 294 89***********.**********9997 PP == domain 7 score: 10.3 bits; conditional E-value: 0.00045 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs + C ++ g+++C C +G+ G+ FUN_001022-T1 309 HNCSVYADCTNSI-GSHKCVCHHGFQGD 335 89***********.************97 PP == domain 8 score: 11.4 bits; conditional E-value: 0.0002 EGF 1 Csp.npCsngGtCvdtprggytCiCpeGytGk 31 C++ ++Cs + C ++ g+y C+C eG+ G+ FUN_001022-T1 345 CKEtHNCSVYADCKNSI-GSYDCTCHEGFEGD 375 888899***********.************97 PP == domain 9 score: 10.4 bits; conditional E-value: 0.00043 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs + C ++ g+y+C+C G+ G+ FUN_001022-T1 390 HNCSVYADCTNNI-GSYNCTCHRGFQGD 416 89***********.************97 PP == domain 10 score: 14.2 bits; conditional E-value: 2.6e-05 EGF 1 Csp..npCsngGtCvdtprggytCiCpeGytGk 31 C++ ++Cs ++ C ++ g+y+C+C eG+ G+ FUN_001022-T1 426 CKEktHKCSVHADCKNSI-GSYNCTCHEGFEGD 457 5553355***********.************97 PP == domain 11 score: 13.8 bits; conditional E-value: 3.6e-05 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs ++ C+++ g+y C+C +G+ G+ FUN_001022-T1 472 HNCSVHADCINSI-GSYDCTCHQGFQGD 498 89***********.************97 PP == domain 12 score: 16.5 bits; conditional E-value: 5e-06 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs ++ C ++ g+y C+C +G++G+ FUN_001022-T1 513 HNCSVHADCTNSI-GSYRCTCHQGFKGD 539 89***********.*************7 PP == domain 13 score: 18.7 bits; conditional E-value: 1.1e-06 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs +++C ++ g ++C+C eG+ G+ FUN_001022-T1 554 DNCSRHAFCTNNV-GAFNCKCLEGFEGN 580 78***********.************97 PP == domain 14 score: 13.2 bits; conditional E-value: 5.6e-05 EGF 1 Cspnp..CsngGtCvdtprggytCiCpeGytGk 31 Cs ++ C+ ++ C+++ g++ CiC GytG+ FUN_001022-T1 590 CSRGThsCDTHASCRNKD-GSHICICDGGYTGD 621 8888889***********.*************7 PP == domain 15 score: 7.6 bits; conditional E-value: 0.0031 EGF 1 Cspnp..CsngGtCvdtprggytCiCpeGyt 29 C +++ C + +C +t+ g+y C C eGy+ FUN_001022-T1 631 CQDGThtCGLNSRCHNTQ-GSYRCPCVEGYS 660 7775555888999*****.***********5 PP == domain 16 score: 15.2 bits; conditional E-value: 1.3e-05 EGF 1 Cspnp.CsngGtCvdtprggytCiCpeGytGk 31 C+ + C+ ++ C +t g+y+C+C +G G+ FUN_001022-T1 672 CNNRRsCHPHASCTNTA-GTYSCRCNPGLRGD 702 77544999999999999.**********9997 PP == domain 17 score: 12.8 bits; conditional E-value: 7.2e-05 EGF 1 Cspnp..CsngGtCvdtprggytCiCpeGytGk 31 C+ + C+ +++C +++ g+y+C C+ G++G+ FUN_001022-T1 712 CTTGDhdCDKNAKCTNNW-GSYHCCCKKGFHGD 743 6654445***********.*************7 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.6 0.0047 10 6 22 .] 68 85 .. 65 85 .. 0.80 2 ? -2.8 0.6 6.8 1.4e+04 3 10 .. 88 95 .. 87 98 .. 0.77 3 ! 14.2 5.3 3.1e-05 0.066 1 22 [] 106 127 .. 106 127 .. 0.95 4 ? -0.7 0.3 1.5 3.1e+03 4 9 .. 131 136 .. 129 141 .. 0.73 5 ! 15.5 3.7 1.1e-05 0.024 1 22 [] 147 168 .. 147 168 .. 0.96 6 ! 11.4 5.3 0.00024 0.51 4 21 .. 191 208 .. 188 208 .. 0.91 7 ? -1.3 0.3 2.3 4.9e+03 4 16 .. 213 222 .. 211 223 .. 0.74 8 ! 8.5 1.0 0.002 4.2 6 22 .] 234 250 .. 231 250 .. 0.87 9 ? 0.2 0.4 0.79 1.7e+03 4 16 .. 254 263 .. 252 264 .. 0.71 10 ! 13.0 5.3 7.5e-05 0.16 1 21 [. 270 290 .. 270 290 .. 0.97 11 ? -1.7 0.3 3.2 6.8e+03 4 16 .. 295 304 .. 293 305 .. 0.69 12 ! 9.2 1.4 0.0012 2.5 6 22 .] 316 332 .. 313 332 .. 0.88 13 ? 0.2 0.4 0.79 1.7e+03 4 16 .. 336 345 .. 334 346 .. 0.71 14 ! 12.5 1.7 0.0001 0.22 6 22 .] 356 372 .. 353 372 .. 0.94 15 ! 12.5 2.5 0.00011 0.23 6 22 .] 397 413 .. 394 413 .. 0.94 16 ? -0.4 0.5 1.2 2.6e+03 4 16 .. 417 426 .. 415 427 .. 0.70 17 ! 12.6 4.1 0.0001 0.21 4 22 .] 436 454 .. 433 454 .. 0.91 18 ! 15.2 3.8 1.5e-05 0.032 4 22 .] 477 495 .. 474 495 .. 0.91 19 ! 15.4 4.0 1.3e-05 0.028 4 22 .] 518 536 .. 515 536 .. 0.91 20 ! 15.8 3.0 9.5e-06 0.02 1 22 [] 556 577 .. 556 577 .. 0.98 21 ? 0.9 0.5 0.48 1e+03 3 16 .. 580 590 .. 579 591 .. 0.75 22 ! 6.8 5.2 0.0066 14 1 22 [] 597 618 .. 597 618 .. 0.91 23 ! 7.4 6.6 0.0042 8.9 3 22 .] 640 659 .. 638 659 .. 0.88 24 ? 1.0 1.1 0.44 9.5e+02 3 10 .. 662 669 .. 660 673 .. 0.80 25 ! 19.2 5.7 8.1e-07 0.0017 1 21 [. 678 698 .. 678 699 .. 0.98 26 ? -3.0 9.3 8.2 1.7e+04 1 22 [] 719 740 .. 719 740 .. 0.92 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0047 hEGF 6 tCv.dgvngykCqCppGy 22 C g n ++CqC+ G+ FUN_001022-T1 68 ICKaIGKNYHSCQCKNGF 85 5666677889*******9 PP == domain 2 score: -2.8 bits; conditional E-value: 6.8 hEGF 3 NGGtCvdg 10 NG C d+ FUN_001022-T1 88 NGSVCFDL 95 89999976 PP == domain 3 score: 14.2 bits; conditional E-value: 3.1e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ + Cv+++++y C+C G+ FUN_001022-T1 106 CSRKADCVNTNGSYNCVCHRGF 127 88899***************98 PP == domain 4 score: -0.7 bits; conditional E-value: 1.5 hEGF 4 GGtCvd 9 G+tC+d FUN_001022-T1 131 GWTCTD 136 99***5 PP == domain 5 score: 15.5 bits; conditional E-value: 1.1e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++ C++ +++y C C +G+ FUN_001022-T1 147 CSLHADCQNSIGSYDCTCHEGF 168 8999*****************9 PP == domain 6 score: 11.4 bits; conditional E-value: 0.00024 hEGF 4 GGtCvdgvngykCqCppG 21 ++ C++ +++y C C++G FUN_001022-T1 191 HADCTNSIGSYDCTCQQG 208 789**************9 PP == domain 7 score: -1.3 bits; conditional E-value: 2.3 hEGF 4 GGtCvdgvngykC 16 G++C+ + ++C FUN_001022-T1 213 GWKCT---DVNEC 222 899**...66666 PP == domain 8 score: 8.5 bits; conditional E-value: 0.002 hEGF 6 tCvdgvngykCqCppGy 22 C + ++++kC+C G+ FUN_001022-T1 234 DCLNSIGSHKCVCHHGF 250 7************7665 PP == domain 9 score: 0.2 bits; conditional E-value: 0.79 hEGF 4 GGtCvdgvngykC 16 G+tC+ + ++C FUN_001022-T1 254 GWTCT---DVNEC 263 99***...44555 PP == domain 10 score: 13.0 bits; conditional E-value: 7.5e-05 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+ ++ C++ +++y C C +G FUN_001022-T1 270 CSFHADCTNSIGSYDCTCHQG 290 999****************99 PP == domain 11 score: -1.7 bits; conditional E-value: 3.2 hEGF 4 GGtCvdgvngykC 16 G++C+ + ++C FUN_001022-T1 295 GWKCT---DVNEC 304 899**...44555 PP == domain 12 score: 9.2 bits; conditional E-value: 0.0012 hEGF 6 tCvdgvngykCqCppGy 22 C++ ++++kC+C G+ FUN_001022-T1 316 DCTNSIGSHKCVCHHGF 332 7************7665 PP == domain 13 score: 0.2 bits; conditional E-value: 0.79 hEGF 4 GGtCvdgvngykC 16 G+tC+ + ++C FUN_001022-T1 336 GWTCT---DVNEC 345 99***...44555 PP == domain 14 score: 12.5 bits; conditional E-value: 0.0001 hEGF 6 tCvdgvngykCqCppGy 22 C + +++y C C +G+ FUN_001022-T1 356 DCKNSIGSYDCTCHEGF 372 7***************9 PP == domain 15 score: 12.5 bits; conditional E-value: 0.00011 hEGF 6 tCvdgvngykCqCppGy 22 C++++++y C C G+ FUN_001022-T1 397 DCTNNIGSYNCTCHRGF 413 7**************98 PP == domain 16 score: -0.4 bits; conditional E-value: 1.2 hEGF 4 GGtCvdgvngykC 16 G+tC+ + ++C FUN_001022-T1 417 GWTCN---DVNEC 426 99***...44555 PP == domain 17 score: 12.6 bits; conditional E-value: 0.0001 hEGF 4 GGtCvdgvngykCqCppGy 22 ++ C + +++y C C +G+ FUN_001022-T1 436 HADCKNSIGSYNCTCHEGF 454 789***************9 PP == domain 18 score: 15.2 bits; conditional E-value: 1.5e-05 hEGF 4 GGtCvdgvngykCqCppGy 22 ++ C++ +++y C C +G+ FUN_001022-T1 477 HADCINSIGSYDCTCHQGF 495 789***************9 PP == domain 19 score: 15.4 bits; conditional E-value: 1.3e-05 hEGF 4 GGtCvdgvngykCqCppGy 22 ++ C++ +++y+C C +G+ FUN_001022-T1 518 HADCTNSIGSYRCTCHQGF 536 789***************9 PP == domain 20 score: 15.8 bits; conditional E-value: 9.5e-06 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++ C+++v+ + C C +G+ FUN_001022-T1 556 CSRHAFCTNNVGAFNCKCLEGF 577 9********************9 PP == domain 21 score: 0.9 bits; conditional E-value: 0.48 hEGF 3 NGGtCvdgvngykC 16 NG+ C+ + ++C FUN_001022-T1 580 NGWLCT---DVNEC 590 9*****...55555 PP == domain 22 score: 6.8 bits; conditional E-value: 0.0066 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C +++C ++ +++ C+C+ Gy FUN_001022-T1 597 CDTHASCRNKDGSHICICDGGY 618 8889**************9776 PP == domain 23 score: 7.4 bits; conditional E-value: 0.0042 hEGF 3 NGGtCvdgvngykCqCppGy 22 + +C+++ ++y+C C +Gy FUN_001022-T1 640 LNSRCHNTQGSYRCPCVEGY 659 4569***************9 PP == domain 24 score: 1.0 bits; conditional E-value: 0.44 hEGF 3 NGGtCvdg 10 NGG C+d FUN_001022-T1 662 NGGVCSDI 669 9****975 PP == domain 25 score: 19.2 bits; conditional E-value: 8.1e-07 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+ +++C+++++ y+C+C+pG FUN_001022-T1 678 CHPHASCTNTAGTYSCRCNPG 698 9*******************9 PP == domain 26 score: -3.0 bits; conditional E-value: 8.2 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C +++C+++ ++y C C+ G+ FUN_001022-T1 719 CDKNAKCTNNWGSYHCCCKKGF 740 77899**************998 PP >> FXa_inhibition Coagulation Factor Xa inhibitory site # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 3.3 0.035 75 10 28 .. 67 86 .. 61 92 .. 0.79 2 ! 9.4 9.0 0.00076 1.6 6 36 .] 104 134 .. 98 134 .. 0.84 3 ! 11.4 7.7 0.00018 0.38 1 28 [. 140 169 .. 140 171 .. 0.91 4 ! 6.8 10.1 0.0052 11 6 32 .. 186 212 .. 179 216 .. 0.77 5 ! 7.7 8.2 0.0027 5.7 6 36 .] 227 257 .. 222 257 .. 0.80 6 ! 8.8 10.8 0.0012 2.6 1 32 [. 263 294 .. 263 298 .. 0.82 7 ! 6.2 9.3 0.0076 16 6 36 .] 309 339 .. 304 339 .. 0.79 8 ! 8.7 8.6 0.0012 2.7 6 28 .. 349 373 .. 343 379 .. 0.81 9 ! 6.6 10.9 0.0057 12 1 36 [] 385 420 .. 385 420 .. 0.84 10 ! 14.3 7.4 2.3e-05 0.049 1 28 [. 426 455 .. 426 467 .. 0.88 11 ! 10.3 7.0 0.00039 0.84 6 28 .. 472 496 .. 461 502 .. 0.82 12 ! 10.5 8.5 0.00034 0.73 1 28 [. 508 537 .. 508 543 .. 0.82 13 ! 11.7 3.6 0.00015 0.32 1 28 [. 549 578 .. 549 583 .. 0.90 14 ? 3.9 13.3 0.041 87 1 36 [] 590 625 .. 590 625 .. 0.88 15 ! 7.4 12.8 0.0032 6.8 1 30 [. 631 662 .. 631 678 .. 0.84 16 ! 7.4 10.9 0.0033 7 5 36 .] 675 706 .. 661 706 .. 0.82 17 ? -1.2 17.2 1.6 3.4e+03 1 36 [] 712 747 .. 712 747 .. 0.92 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.035 FXa_inhibition 10 hlClnt.pggytCsCpeGye 28 +C++ + ++C+C +G++ FUN_001022-T1 67 AICKAIgKNYHSCQCKNGFQ 86 799999566699******98 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00076 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGyeLsdDgktC 36 +gCs C+nt g+y C C+ G++ Dg tC FUN_001022-T1 104 NGCSrkADCVNTNGSYNCVCHRGFQ--GDGWTC 134 69997778***************99..666677 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00018 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+++ + Cs C n+ g+y C+C+eG+e FUN_001022-T1 140 CKEKTHNCSlhADCQNSIGSYDCTCHEGFE 169 99999****9556***************97 PP == domain 4 score: 6.8 bits; conditional E-value: 0.0052 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGyeLsdD 32 + Cs C+n+ g+y C+C++G++ D FUN_001022-T1 186 HNCSvhADCTNSIGSYDCTCQQGHQ--GD 212 56888445***************98..44 PP == domain 5 score: 7.7 bits; conditional E-value: 0.0027 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGyeLsdDgktC 36 + Cs Cln+ g+++C C++G++ Dg tC FUN_001022-T1 227 HNCSvyADCLNSIGSHKCVCHHGFQ--GDGWTC 257 56885555***************99..666677 PP == domain 6 score: 8.8 bits; conditional E-value: 0.0012 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdD 32 C+++ + Cs C+n+ g+y C+C++G++ D FUN_001022-T1 263 CKEKIHNCSfhADCTNSIGSYDCTCHQGHQ--GD 294 8888899**8445***************98..44 PP == domain 7 score: 6.2 bits; conditional E-value: 0.0076 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGyeLsdDgktC 36 + Cs C+n+ g+++C C++G++ Dg tC FUN_001022-T1 309 HNCSvyADCTNSIGSHKCVCHHGFQ--GDGWTC 339 56885556***************99..666677 PP == domain 8 score: 8.7 bits; conditional E-value: 0.0012 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGye 28 + Cs C+n+ g+y C+C+eG+e FUN_001022-T1 349 HNCSvyADCKNSIGSYDCTCHEGFE 373 56885555***************98 PP == domain 9 score: 6.6 bits; conditional E-value: 0.0057 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 C+ + Cs C+n+ g+y C+C+ G++ Dg tC FUN_001022-T1 385 CKRSMHNCSvyADCTNNIGSYNCTCHRGFQ--GDGWTC 420 7777788996666***************99..666677 PP == domain 10 score: 14.3 bits; conditional E-value: 2.3e-05 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+++ ++Cs C+n+ g+y C+C+eG+e FUN_001022-T1 426 CKEKTHKCSvhADCKNSIGSYNCTCHEGFE 455 9999*****9556***************98 PP == domain 11 score: 10.3 bits; conditional E-value: 0.00039 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGye 28 + Cs C+n+ g+y C+C++G++ FUN_001022-T1 472 HNCSvhADCINSIGSYDCTCHQGFQ 496 56888445***************98 PP == domain 12 score: 10.5 bits; conditional E-value: 0.00034 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+ + + Cs C+n+ g+y+C+C++G++ FUN_001022-T1 508 CKREIHNCSvhADCTNSIGSYRCTCHQGFK 537 6666678998445***************98 PP == domain 13 score: 11.7 bits; conditional E-value: 0.00015 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+ + Cs +C+n+ g + C C eG+e FUN_001022-T1 549 CKMRVDNCSrhAFCTNNVGAFNCKCLEGFE 578 7778889*9978****************98 PP == domain 14 score: 3.9 bits; conditional E-value: 0.041 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 Cs + C+ C+n+ g++ C C+ Gy+ Dg tC FUN_001022-T1 590 CSRGTHSCDthASCRNKDGSHICICDGGYT--GDGETC 625 7778889997557*****************..999999 PP == domain 15 score: 7.4 bits; conditional E-value: 0.0032 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLs 30 C++ + C+ C+nt+g+y+C C eGy+ + FUN_001022-T1 631 CQDGTHTCGlnSRCHNTQGSYRCPCVEGYSVN 662 6666677888899****************965 PP == domain 16 score: 7.4 bits; conditional E-value: 0.0033 FXa_inhibition 5 NggCs..hlClntpggytCsCpeGyeLsdDgktC 36 C C+nt g+y+C+C +G + Dg +C FUN_001022-T1 675 RRSCHphASCTNTAGTYSCRCNPGLR--GDGISC 706 445777557***************66..888888 PP == domain 17 score: -1.2 bits; conditional E-value: 1.6 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 C + + C+ C+n+ g+y+C C +G++ Dgk+C FUN_001022-T1 712 CTTGDHDCDknAKCTNNWGSYHCCCKKGFH--GDGKEC 747 8889999*97788***************99..899999 PP >> ADGRF3_N ADGRF3-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 6.5 3.2e-05 0.069 4 40 .. 69 108 .. 66 115 .. 0.82 2 ! 6.2 12.0 0.0092 20 3 43 .. 111 148 .. 109 155 .. 0.84 3 ? 2.7 10.0 0.12 2.5e+02 3 42 .. 152 188 .. 150 197 .. 0.81 4 ? 1.6 10.8 0.25 5.4e+02 3 42 .. 193 229 .. 191 238 .. 0.80 5 ? 4.2 10.6 0.039 83 4 42 .. 235 270 .. 232 278 .. 0.82 6 ? 0.2 11.7 0.67 1.4e+03 3 42 .. 275 311 .. 273 318 .. 0.84 7 ? 4.3 12.0 0.035 75 3 42 .. 316 351 .. 314 358 .. 0.83 8 ? 4.8 10.3 0.024 52 3 43 .. 356 393 .. 354 398 .. 0.86 9 ? 5.4 12.7 0.017 36 3 43 .. 397 434 .. 395 439 .. 0.87 10 ! 6.9 9.0 0.0054 12 3 46 .. 438 482 .. 436 486 .. 0.79 11 ! 8.2 7.5 0.0022 4.6 4 42 .. 480 515 .. 477 522 .. 0.82 12 ? 5.7 8.2 0.013 27 3 42 .. 520 556 .. 518 563 .. 0.83 13 ! 10.2 7.8 0.00051 1.1 4 43 .. 562 598 .. 559 606 .. 0.79 14 ! 11.3 4.3 0.00024 0.52 3 42 .. 602 638 .. 599 640 .. 0.87 15 ! 11.3 10.3 0.00024 0.51 3 45 .. 643 685 .. 641 688 .. 0.84 16 ? 5.0 9.0 0.021 45 3 44 .. 683 725 .. 681 728 .. 0.78 17 ? 0.4 8.2 0.6 1.3e+03 3 30 .. 724 750 .. 722 754 .. 0.83 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 3.2e-05 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqess.e..eq 40 C++ g++ +C+C++g+q n svC ++C +++ + ++ FUN_001022-T1 69 CKAIGKNYHSCQCKNGFQGNGSVCFDLNECLSEElNgcSR 108 999999************************9987433344 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0092 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsCs 43 +C ++ ng+++C C+ g+q + +C+ ++C+e++ ++Cs FUN_001022-T1 111 DCVNT-NGSYNCVCHRGFQGDGWTCTDVDECKEKT--HNCS 148 57766.799***********************998..5554 PP == domain 3 score: 2.7 bits; conditional E-value: 0.12 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s g++ C+C++g++ +C+ ++C++ ++C FUN_001022-T1 152 DCQNS-IGSYDCTCHEGFEGVGWACTDVNECKRGI--HNC 188 68887.588**********************9876..344 PP == domain 4 score: 1.6 bits; conditional E-value: 0.25 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s g++ C+C++g+q + C+ ++C++ ++C FUN_001022-T1 193 DCTNS-IGSYDCTCQQGHQGDGWKCTDVNECRRGI--HNC 229 58776.588**********************9877..444 PP == domain 5 score: 4.2 bits; conditional E-value: 0.039 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 C +s g+ +C C++g+q + +C+ ++C+e+ ++C FUN_001022-T1 235 CLNS-IGSHKCVCHHGFQGDGWTCTDVNECKEKI--HNC 270 5554.5789**********************998..455 PP == domain 6 score: 0.2 bits; conditional E-value: 0.67 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s g++ C+C++g+q + C+ ++C++ ++C FUN_001022-T1 275 DCTNS-IGSYDCTCHQGHQGDGWKCTDVNECKRGI--HNC 311 58776.588**********************9876..455 PP == domain 7 score: 4.3 bits; conditional E-value: 0.035 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s g+ +C C++g+q + +C+ ++C+e++ +C FUN_001022-T1 316 DCTNS-IGSHKCVCHHGFQGDGWTCTDVNECKETH---NC 351 58776.5789**********************999...33 PP == domain 8 score: 4.8 bits; conditional E-value: 0.024 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsCs 43 +C++s g++ C+C++g++ + +C+ ++C++s ++Cs FUN_001022-T1 356 DCKNS-IGSYDCTCHEGFEGDGWACKDVNECKRSM--HNCS 393 68887.588***********************997..6664 PP == domain 9 score: 5.4 bits; conditional E-value: 0.017 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsCs 43 +C+++ g+++C+C+ g+q + +C+ ++C+e++ ++Cs FUN_001022-T1 397 DCTNNI-GSYNCTCHRGFQGDGWTCNDVNECKEKT--HKCS 434 688875.88***********************998..6664 PP == domain 10 score: 6.9 bits; conditional E-value: 0.0054 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqess.e.eqsCsCli 46 +C++s g+++C+C++g++ + +C+ ++C++ + + + +C++ FUN_001022-T1 438 DCKNSI-GSYNCTCHEGFEGDGWACKDVNECKRGIhNcSVHADCIN 482 688875.88***********************87722345556665 PP == domain 11 score: 8.2 bits; conditional E-value: 0.0022 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 C +s g++ C+C++g+q + vC+ ++C+++ ++C FUN_001022-T1 480 CINS-IGSYDCTCHQGFQGDGFVCKDVNECKREI--HNC 515 5444.5889**********************988..555 PP == domain 12 score: 5.7 bits; conditional E-value: 0.013 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s g+++C+C++g++ + +Cs ++C+ + ++C FUN_001022-T1 520 DCTNS-IGSYRCTCHQGFKGDGWACSDIDECKMRV--DNC 556 58776.588**********************9876..455 PP == domain 13 score: 10.2 bits; conditional E-value: 0.00051 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesseeqsCs 43 C+++ g ++C+C++g++ n +C+ ++C++ + +sC+ FUN_001022-T1 562 CTNN-VGAFNCKCLEGFEGNGWLCTDVNECSRGT--HSCD 598 7776.588***********************776..4443 PP == domain 14 score: 11.3 bits; conditional E-value: 0.00024 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 C+++ +g+ C C gY+ + ++C+ ++Cq+ + ++C FUN_001022-T1 602 SCRNK-DGSHICICDGGYTGDGETCKDIDECQDGT--HTC 638 58876.68899*********************987..666 PP == domain 15 score: 11.3 bits; conditional E-value: 0.00024 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqess.eeqsCsCl 45 C++++ g+++C C +gY+ n vCs ++C++++ + + sC FUN_001022-T1 643 RCHNTQ-GSYRCPCVEGYSVNGGVCSDINECNNRRsCHPHASCT 685 599885.88***********************999446666665 PP == domain 16 score: 5.0 bits; conditional E-value: 0.021 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqess.e.eqsCsC 44 C+++ g+++C+C++g + + Cs y++C++ + + +++ +C FUN_001022-T1 683 SCTNT-AGTYSCRCNPGLRGDGISCSDYDECTTGDhDcDKNAKC 725 58887.588**********************9776222445555 PP == domain 17 score: 0.4 bits; conditional E-value: 0.6 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCsky 30 +C+++ g+++C C++g++ + + C++ FUN_001022-T1 724 KCTNNW-GSYHCCCKKGFHGDGKECKAS 750 698886.78*********9999888875 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 6.5 2.5e-05 0.052 6 40 .. 62 92 .. 56 93 .. 0.86 2 ! 6.0 3.2 0.0085 18 7 41 .] 106 135 .. 104 135 .. 0.88 3 ? 0.1 9.4 0.58 1.2e+03 2 33 .. 181 210 .. 174 217 .. 0.80 4 ? 4.3 5.9 0.028 60 5 41 .] 227 258 .. 215 258 .. 0.83 5 ? -1.0 7.5 1.3 2.7e+03 1 32 [. 262 291 .. 262 299 .. 0.78 6 ! 6.4 7.1 0.0063 13 2 41 .] 304 340 .. 292 340 .. 0.86 7 ? 4.0 12.1 0.035 74 1 33 [. 344 373 .. 344 386 .. 0.87 8 ? 5.4 9.1 0.013 28 2 36 .. 385 416 .. 378 421 .. 0.82 9 ? 4.0 12.7 0.035 74 1 33 [. 425 455 .. 425 468 .. 0.88 10 ? 1.8 11.5 0.17 3.6e+02 2 39 .. 467 507 .. 460 509 .. 0.75 11 ? 5.2 8.3 0.015 32 2 33 .. 508 537 .. 501 544 .. 0.82 12 ? 5.0 5.1 0.017 37 6 33 .. 555 578 .. 548 585 .. 0.83 13 ! 7.2 7.8 0.0035 7.6 7 41 .] 597 626 .. 589 626 .. 0.89 14 ! 19.0 6.5 7.1e-07 0.0015 1 40 [. 630 666 .. 630 667 .. 0.92 15 ! 10.3 3.0 0.00038 0.81 1 32 [. 671 699 .. 671 707 .. 0.87 16 ? -1.3 0.1 1.7 3.5e+03 6 16 .. 705 715 .. 700 718 .. 0.82 17 ? 2.7 15.0 0.091 1.9e+02 6 41 .] 718 748 .. 706 748 .. 0.88 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.5e-05 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +C +n++Ck n++ C+C++G+ n+++C FUN_001022-T1 62 VCDVNAICKAI---GKNYHSCQCKNGFQ-GNGSVC 92 6********99...789999********.****99 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0085 Plasmod_Pvs28 7 CgengkCklglpqnsnhykCsCniGyvllnenkCt 41 C ++ C ++ +++y C C G+ ++ +Ct FUN_001022-T1 106 CSRKADCVNT----NGSYNCVCHRGFQ-GDGWTCT 135 777889****....***********98.8888886 PP == domain 3 score: 0.1 bits; conditional E-value: 0.58 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCniGyv 33 C+ +C +++ C++ ++y C C G FUN_001022-T1 181 CKRgiHNCSVHADCTNS----IGSYDCTCQQGHQ 210 5556668**********....********98865 PP == domain 4 score: 4.3 bits; conditional E-value: 0.028 Plasmod_Pvs28 5 KaCgengkCklglpqnsnhykCsCniGyvllnenkCt 41 +C +++ C + +++kC C G+ ++ +Ct FUN_001022-T1 227 HNCSVYADCLNS----IGSHKCVCHHGFQ-GDGWTCT 258 58**********....***********98.8888886 PP == domain 5 score: -1.0 bits; conditional E-value: 1.3 Plasmod_Pvs28 1 kCql..KaCgengkCklglpqnsnhykCsCniGy 32 +C++ +C ++ C++ ++y C C G FUN_001022-T1 262 ECKEkiHNCSFHADCTNS----IGSYDCTCHQGH 291 5788555799999*****....********9885 PP == domain 6 score: 6.4 bits; conditional E-value: 0.0063 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCniGyvllnenkCt 41 C+ +C +++ C++ +++kC C G+ ++ +Ct FUN_001022-T1 304 CKRgiHNCSVYADCTNS----IGSHKCVCHHGFQ-GDGWTCT 340 4446668**********....***********98.8888886 PP == domain 7 score: 4.0 bits; conditional E-value: 0.035 Plasmod_Pvs28 1 kCql.KaCgengkCklglpqnsnhykCsCniGyv 33 +C++ +C +++ Ck+ ++y C C +G+ FUN_001022-T1 344 ECKEtHNCSVYADCKNS----IGSYDCTCHEGFE 373 5888889**********....**********995 PP == domain 8 score: 5.4 bits; conditional E-value: 0.013 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCniGyvlln 36 C+ +C +++ C+++ ++y C C G+ + FUN_001022-T1 385 CKRsmHNCSVYADCTNN----IGSYNCTCHRGFQ-GD 416 5556668**********....********99986.55 PP == domain 9 score: 4.0 bits; conditional E-value: 0.035 Plasmod_Pvs28 1 kCql...KaCgengkCklglpqnsnhykCsCniGyv 33 +C++ K C +++ Ck+ ++y C C +G+ FUN_001022-T1 425 ECKEkthK-CSVHADCKNS----IGSYNCTCHEGFE 455 69998888.**********....**********995 PP == domain 10 score: 1.8 bits; conditional E-value: 0.17 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCn.....iGyvllnenk 39 C+ +C +++ C++ ++y C C +G+v ++ n FUN_001022-T1 467 CKRgiHNCSVHADCINS----IGSYDCTCHqgfqgDGFVCKDVNE 507 5556668**********....*********555555555555555 PP == domain 11 score: 5.2 bits; conditional E-value: 0.015 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCniGyv 33 C+ +C +++ C++ ++y+C C G++ FUN_001022-T1 508 CKReiHNCSVHADCTNS----IGSYRCTCHQGFK 537 4446668**********....***********98 PP == domain 12 score: 5.0 bits; conditional E-value: 0.017 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyv 33 +C ++ C+++ ++++ C+C +G+ FUN_001022-T1 555 NCSRHAFCTNN----VGAFNCKCLEGFE 578 6899999****....*********9996 PP == domain 13 score: 7.2 bits; conditional E-value: 0.0035 Plasmod_Pvs28 7 CgengkCklglpqnsnhykCsCniGyvllnenkCt 41 C ++ C + ++++ C C+ Gy+ ++++C+ FUN_001022-T1 597 CDTHASCRNK----DGSHICICDGGYT-GDGETCK 626 888999****....*************.******6 PP == domain 14 score: 19.0 bits; conditional E-value: 7.1e-07 Plasmod_Pvs28 1 kCql..KaCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +Cq +Cg n C ++ +++y+C C +Gy +n+++C FUN_001022-T1 630 ECQDgtHTCGLNSRCHNT----QGSYRCPCVEGYS-VNGGVC 666 58888878**********....*************.****** PP == domain 15 score: 10.3 bits; conditional E-value: 0.00038 Plasmod_Pvs28 1 kCql.KaCgengkCklglpqnsnhykCsCniGy 32 +C++ C ++ C+++ ++y C Cn+G FUN_001022-T1 671 ECNNrRSCHPHASCTNT----AGTYSCRCNPGL 699 5777767999*******....*********996 PP == domain 16 score: -1.3 bits; conditional E-value: 1.7 Plasmod_Pvs28 6 aCgengkCklg 16 C ++ +C+ g FUN_001022-T1 705 SCSDYDECTTG 715 699*****977 PP == domain 17 score: 2.7 bits; conditional E-value: 0.091 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkCt 41 +C n+kC+++ ++y C C++G+ +++ C+ FUN_001022-T1 718 DCDKNAKCTNN----WGSYHCCCKKGFH-GDGKECK 748 7**********....************9.9999995 PP >> EGF_TEN Teneurin EGF domain [No individual domains that satisfy reporting thresholds (although complete target did)] >> UxuA D-mannonate dehydratase (UxuA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 0.48 1e+03 34 70 .. 124 160 .. 119 216 .. 0.72 2 ? 4.9 0.0 0.0064 14 32 74 .. 245 287 .. 227 363 .. 0.77 3 ? 1.9 0.0 0.052 1.1e+02 34 105 .. 451 523 .. 441 534 .. 0.77 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.48 UxuA 34 hdipagevWeleeikklkeeiekaglklevvesvnvh 70 h+ ++g+ W ++ + ke+ + l+++ +s+ + FUN_001022-T1 124 HRGFQGDGWTCTDVDECKEKTHNCSLHADCQNSIGSY 160 6778899999999999999999999999887776554 PP == domain 2 score: 4.9 bits; conditional E-value: 0.0064 UxuA 32 alhdipagevWeleeikklkeeiekaglklevvesvnvhedik 74 + h+ ++g+ W ++ + ke+i + ++++ +s+ ++ FUN_001022-T1 245 VCHHGFQGDGWTCTDVNECKEKIHNCSFHADCTNSIGSYDCTC 287 5688999************************999987766444 PP == domain 3 score: 1.9 bits; conditional E-value: 0.052 UxuA 34 hdipagevWeleeikklkeeiekaglklevvesvnvhediklgtetrdryi.enykqtirnlakiGvkvvCYn 105 h+ + g+ W +++ + k i + ++++ ++s+ ++ + + d ++ +++++ r++ ++ v+ C n FUN_001022-T1 451 HEGFEGDGWACKDVNECKRGIHNCSVHADCINSIGSYDCTCHQGFQGDGFVcKDVNECKREIHNCSVHADCTN 523 67789****************************9887755544444444432566666677777777776666 PP >> GPR158_179_EC GPR158/179 extracellular domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 2.7 1.1 2.3e+03 58 95 .. 48 85 .. 26 86 .. 0.63 2 ? 2.0 7.6 0.22 4.7e+02 61 95 .. 92 127 .. 80 128 .. 0.70 3 ? 10.9 5.3 0.00036 0.76 63 95 .. 136 168 .. 130 169 .. 0.93 4 ? 7.1 5.9 0.0058 12 63 95 .. 177 209 .. 173 210 .. 0.93 5 ? 4.0 4.4 0.051 1.1e+02 63 95 .. 218 250 .. 212 251 .. 0.92 6 ? 8.2 6.3 0.0026 5.5 63 95 .. 259 291 .. 253 292 .. 0.92 7 ? 5.5 5.5 0.018 38 63 95 .. 300 332 .. 294 333 .. 0.93 8 ? 7.3 5.9 0.005 11 63 95 .. 341 372 .. 335 373 .. 0.89 9 ? 9.9 6.0 0.00076 1.6 62 95 .. 380 413 .. 375 414 .. 0.93 10 ? 11.6 6.3 0.00023 0.49 63 95 .. 422 454 .. 416 455 .. 0.93 11 ? 8.3 4.6 0.0024 5.1 62 95 .. 462 495 .. 457 496 .. 0.92 12 ? 10.9 5.8 0.00036 0.77 62 95 .. 503 536 .. 498 537 .. 0.93 13 ? 4.9 3.2 0.027 57 63 95 .. 545 577 .. 539 578 .. 0.92 14 ? 2.3 4.6 0.17 3.7e+02 63 95 .. 586 618 .. 580 619 .. 0.88 15 ? 4.8 6.0 0.029 62 62 95 .. 626 659 .. 621 660 .. 0.83 16 ? 6.5 4.8 0.0085 18 62 94 .. 667 698 .. 662 699 .. 0.88 17 ? 3.5 9.6 0.077 1.6e+02 64 96 .] 709 741 .. 704 741 .. 0.87 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.1 GPR158_179_EC 58 dnvfagthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + a ++ C l+ v+ k ++ +C+Ck+gf FUN_001022-T1 48 KRSLATSDDCWLKRVCDVNAICKAIGKNYHSCQCKNGF 85 4667778888875443344555666667778******9 PP == domain 2 score: 2.0 bits; conditional E-value: 0.22 GPR158_179_EC 61 fagthkCkl.estqCvpikgkGfrlgsYkCvCkkgf 95 + ++C + e C ++ + gsY+CvC++gf FUN_001022-T1 92 CFDLNECLSeELNGCSRKADCVNTNGSYNCVCHRGF 127 4455667541456688888889999**********9 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00036 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck+++ +C +++ + gsY C+C++gf FUN_001022-T1 136 DVDECKEKTHNCSLHADCQNSIGSYDCTCHEGF 168 6789****************************9 PP == domain 4 score: 7.1 bits; conditional E-value: 0.0058 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck+ +C +++ + gsY C+C++g+ FUN_001022-T1 177 DVNECKRGIHNCSVHADCTNSIGSYDCTCQQGH 209 6789***************************96 PP == domain 5 score: 4.0 bits; conditional E-value: 0.051 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++C++ +C ++ + gs kCvC++gf FUN_001022-T1 218 DVNECRRGIHNCSVYADCLNSIGSHKCVCHHGF 250 6689****************************9 PP == domain 6 score: 8.2 bits; conditional E-value: 0.0026 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck++ +C ++++ + gsY C+C++g+ FUN_001022-T1 259 DVNECKEKIHNCSFHADCTNSIGSYDCTCHQGH 291 6789**************************996 PP == domain 7 score: 5.5 bits; conditional E-value: 0.018 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck+ +C ++ + gs kCvC++gf FUN_001022-T1 300 DVNECKRGIHNCSVYADCTNSIGSHKCVCHHGF 332 6789****************************9 PP == domain 8 score: 7.3 bits; conditional E-value: 0.005 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck e+ +C ++ + gsY C+C++gf FUN_001022-T1 341 DVNECK-ETHNCSVYADCKNSIGSYDCTCHEGF 372 668999.5999*********************9 PP == domain 9 score: 9.9 bits; conditional E-value: 0.00076 GPR158_179_EC 62 agthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 ++ ++Ck++ +C ++ + gsY+C+C++gf FUN_001022-T1 380 KDVNECKRSMHNCSVYADCTNNIGSYNCTCHRGF 413 57799****************************9 PP == domain 10 score: 11.6 bits; conditional E-value: 0.00023 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck+++ +C +++ + gsY+C+C++gf FUN_001022-T1 422 DVNECKEKTHKCSVHADCKNSIGSYNCTCHEGF 454 6789****************************9 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0024 GPR158_179_EC 62 agthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 ++ ++Ck+ +C +++ + gsY C+C++gf FUN_001022-T1 462 KDVNECKRGIHNCSVHADCINSIGSYDCTCHQGF 495 56789****************************9 PP == domain 12 score: 10.9 bits; conditional E-value: 0.00036 GPR158_179_EC 62 agthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 ++ ++Ck+e +C +++ + gsY+C+C++gf FUN_001022-T1 503 KDVNECKREIHNCSVHADCTNSIGSYRCTCHQGF 536 67899****************************9 PP == domain 13 score: 4.9 bits; conditional E-value: 0.027 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++Ck++ +C ++ ++g+++C+C +gf FUN_001022-T1 545 DIDECKMRVDNCSRHAFCTNNVGAFNCKCLEGF 577 6689***************************99 PP == domain 14 score: 2.3 bits; conditional E-value: 0.17 GPR158_179_EC 63 gthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 + ++C++ + +C ++++ + gs C C g+ FUN_001022-T1 586 DVNECSRGTHSCDTHASCRNKDGSHICICDGGY 618 6689999999999999999999*******9998 PP == domain 15 score: 4.8 bits; conditional E-value: 0.029 GPR158_179_EC 62 agthkCklestqCvpikgkGfrlgsYkCvCkkgf 95 ++ ++C+ + +C ++ ++gsY+C C +g+ FUN_001022-T1 626 KDIDECQDGTHTCGLNSRCHNTQGSYRCPCVEGY 659 45678888888888888888899**********9 PP == domain 16 score: 6.5 bits; conditional E-value: 0.0085 GPR158_179_EC 62 agthkCklestqCvpikgkGfrlgsYkCvCkkg 94 ++ ++C++ +C+p+++ ++g+Y+C+C++g FUN_001022-T1 667 SDINECNN-RRSCHPHASCTNTAGTYSCRCNPG 698 67789*95.89*******************998 PP == domain 17 score: 3.5 bits; conditional E-value: 0.077 GPR158_179_EC 64 thkCklestqCvpikgkGfrlgsYkCvCkkgfy 96 ++C++ C + ++ + gsY+C Ckkgf+ FUN_001022-T1 709 YDECTTGDHDCDKNAKCTNNWGSYHCCCKKGFH 741 57899999999999999999***********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (777 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1004 (0.0393032); expected 510.9 (0.02) Passed bias filter: 343 (0.0134273); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 26 (0.00101781); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.47u 0.39s 00:00:00.86 Elapsed: 00:00:00.44 # Mc/sec: 7063.11 // Query: FUN_001023-T1 [L=476] Description: FUN_001023 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-86 282.5 183.0 4.1e-11 43.4 9.1 9.4 10 EGF_3 EGF domain 6.9e-75 247.5 160.3 4.3e-11 43.3 9.8 9.3 9 EGF_CA Calcium-binding EGF domain 1.4e-58 194.8 94.8 9e-09 35.5 1.7 9.7 9 cEGF Complement Clr-like EGF-like 1.5e-29 102.1 138.6 7.4e-07 29.6 6.6 9.2 9 EGF_MSP1_1 MSP1 EGF domain 1 6.7e-29 100.2 137.7 0.00044 20.9 8.7 10.0 9 EGF EGF-like domain 2.3e-16 60.0 130.8 0.00012 22.9 4.2 11.8 12 hEGF Human growth factor-like EGF 7.9e-15 55.5 116.3 0.024 15.5 8.0 9.5 9 ADGRF3_N ADGRF3-like, N-terminal domain 2.3e-12 47.3 158.3 0.0082 16.8 12.5 9.4 9 FXa_inhibition Coagulation Factor Xa inhibitory site 1.9e-07 31.5 135.1 0.17 12.5 5.3 9.8 10 Plasmod_Pvs28 Pvs28 EGF domain 0.0013 18.9 129.0 2.6e+04 -13.5 129.1 3.0 0 EGF_TEN Teneurin EGF domain ------ inclusion threshold ------ 0.059 13.9 110.7 0.12 13.0 2.2 10.4 9 EGF_Mua-3 Transmembrane cell adhesion receptor mua-3-li 8.2 7.3 4.8 92 4.0 0.1 3.7 3 RecD_N RecBCD enzyme subunit RecD, N-terminal domain Domain annotation for each model (and alignments): >> EGF_3 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 5.6 1.2e+04 11 18 .. 37 44 .. 36 46 .. 0.79 2 ! 25.8 12.8 5.9e-09 1.3e-05 4 36 .] 87 120 .. 85 120 .. 0.94 3 ! 39.2 13.7 3.9e-13 8.2e-10 4 36 .] 128 160 .. 126 160 .. 0.97 4 ! 41.7 14.6 6.4e-14 1.4e-10 1 36 [] 166 201 .. 166 201 .. 1.00 5 ! 36.7 11.5 2.3e-12 5e-09 1 36 [] 207 242 .. 207 242 .. 0.98 6 ! 40.2 12.8 1.9e-13 4e-10 1 36 [] 248 283 .. 248 283 .. 0.98 7 ! 39.3 12.4 3.6e-13 7.6e-10 1 36 [] 289 324 .. 289 324 .. 0.98 8 ! 36.6 11.9 2.5e-12 5.3e-09 1 36 [] 330 365 .. 330 365 .. 0.99 9 ! 43.4 9.1 1.9e-14 4.1e-11 7 36 .] 376 405 .. 371 405 .. 0.95 10 ! 34.4 16.6 1.3e-11 2.7e-08 1 36 [] 411 446 .. 411 446 .. 0.99 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 5.6 EGF_3 11 nAtCtnte 18 +A C+n++ FUN_001023-T1 37 KALCKNVA 44 699*9985 PP == domain 2 score: 25.8 bits; conditional E-value: 5.9e-09 EGF_3 4 nnggChanAtCtnteg.sfkCtCkagytGdGvtC 36 n++ C++nA C+ ++ ++C+C+ gy+G+G +C FUN_001023-T1 87 NKTLCDVNAACKAIDHnHHTCQCNVGYHGNGSVC 120 6679****************************** PP == domain 3 score: 39.2 bits; conditional E-value: 3.9e-13 EGF_3 4 nnggChanAtCtntegsfkCtCkagytGdGvtC 36 + ++C++nA+C+nt gsf+C+C +g++G+G+tC FUN_001023-T1 128 GRHNCSENARCKNTTGSFNCECLQGFQGNGTTC 160 579****************************** PP == domain 4 score: 41.7 bits; conditional E-value: 6.4e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 Cs+n ++C+++A C+nt g ++C+C +g++GdG+tC FUN_001023-T1 166 CSDNLHNCSQHAYCNNTIGAYNCSCFSGFEGDGKTC 201 ************************************ PP == domain 5 score: 36.7 bits; conditional E-value: 2.3e-12 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C++ + C ++A C+nteg f+CtC +gy+GdG++C FUN_001023-T1 207 CKVMLHRCNKHAFCSNTEGAFHCTCLNGYQGDGRNC 242 99999******************************* PP == domain 6 score: 40.2 bits; conditional E-value: 1.9e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+++A+Ctn +gs+ CtC++g++GdG+ C FUN_001023-T1 248 CNMEIHNCSVHADCTNSNGSYGCTCHQGFEGDGWAC 283 99999******************************9 PP == domain 7 score: 39.3 bits; conditional E-value: 3.6e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+ +A C+n++gs++C+C++gy+GdG+tC FUN_001023-T1 289 CKMRVDNCGTHASCQNIDGSYVCSCSRGYKGDGHTC 324 99999******************************* PP == domain 8 score: 36.6 bits; conditional E-value: 2.5e-12 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+++++gC an +C nt gs++C+C +gy+G+G +C FUN_001023-T1 330 CREGTHGCRANSRCINTPGSYSCRCVEGYRGNGEYC 365 ************************************ PP == domain 9 score: 43.4 bits; conditional E-value: 1.9e-14 EGF_3 7 gChanAtCtntegsfkCtCkagytGdGvtC 36 C+ +A Ctnt+gs+kC+C++g++GdG++C FUN_001023-T1 376 SCDLHASCTNTKGSYKCRCNPGFQGDGISC 405 7***************************** PP == domain 10 score: 34.4 bits; conditional E-value: 1.3e-11 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C +nA+C n +gs++C+C++gy+G+G+ C FUN_001023-T1 411 CEAGDHDCNKNAKCVNRKGSYSCSCNKGYRGNGKDC 446 9*********************************99 PP >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 8.0 0.54 1.2e+03 5 43 .] 85 120 .. 80 120 .. 0.77 2 ! 36.8 11.0 2.3e-12 4.9e-09 1 43 [] 122 160 .. 122 160 .. 0.94 3 ! 35.9 12.9 4.2e-12 8.9e-09 1 43 [] 162 201 .. 162 201 .. 0.97 4 ! 36.8 9.1 2.2e-12 4.8e-09 1 43 [] 203 242 .. 203 242 .. 0.96 5 ! 33.2 12.3 2.9e-11 6.2e-08 1 43 [] 244 283 .. 244 283 .. 0.92 6 ! 36.6 10.2 2.7e-12 5.7e-09 1 43 [] 285 324 .. 285 324 .. 0.96 7 ! 43.3 9.8 2e-14 4.3e-11 1 41 [. 326 363 .. 326 365 .. 0.91 8 ! 37.7 8.1 1.2e-12 2.5e-09 1 43 [] 367 405 .. 367 405 .. 0.91 9 ! 38.4 14.8 7.1e-13 1.5e-09 1 43 [] 407 446 .. 407 447 .. 0.93 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.54 EGF_CA 5 CaegthnCpdentvCvNteGs.feCvCeegyennedgkkC 43 C++ t C d n+ C + +C+C+ gy+ +g+ C FUN_001023-T1 85 CRNKT-LC-DVNAACKAIDHNhHTCQCNVGYH--GNGSVC 120 88866.99.699999988765268*******9..555555 PP == domain 2 score: 36.8 bits; conditional E-value: 2.3e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D++EC +hnC +en+ C Nt Gsf+C+C +g++ +g++C FUN_001023-T1 122 DLNECLG-RHNC-SENARCKNTTGSFNCECLQGFQ--GNGTTC 160 9****97.88**.8*********************..888888 PP == domain 3 score: 35.9 bits; conditional E-value: 4.2e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 DvdEC + hnC ++++ C+Nt+G ++C+C +g+e dgk+C FUN_001023-T1 162 DVDECSDNLHNC-SQHAYCNNTIGAYNCSCFSGFE--GDGKTC 201 9***********.8*********************..999999 PP == domain 4 score: 36.8 bits; conditional E-value: 2.2e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 DvdEC+ h C ++++ C+NteG f+C+C +gy+ dg +C FUN_001023-T1 203 DVDECKVMLHRC-NKHAFCSNTEGAFHCTCLNGYQ--GDGRNC 242 9***********.8*********************..888888 PP == domain 5 score: 33.2 bits; conditional E-value: 2.9e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ + hnC + ++ C+N++Gs+ C+C++g+e dg +C FUN_001023-T1 244 DVNECNMEIHNC-SVHADCTNSNGSYGCTCHQGFE--GDGWAC 283 9***********.8********************9..666555 PP == domain 6 score: 36.6 bits; conditional E-value: 2.7e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D+dEC+ +nC +++C+N +Gs+ C+C++gy+ dg++C FUN_001023-T1 285 DIDECKMRVDNC-GTHASCQNIDGSYVCSCSRGYK--GDGHTC 324 9***********.79********************..999998 PP == domain 7 score: 43.3 bits; conditional E-value: 2e-14 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgk 41 D++EC+egth C ++n+ C+Nt Gs++C+C egy+ +g+ FUN_001023-T1 326 DINECREGTHGC-RANSRCINTPGSYSCRCVEGYR--GNGE 363 9***********.9********************9..4444 PP == domain 8 score: 37.7 bits; conditional E-value: 1.2e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D+dEC++ + +C d +++C+Nt+Gs++C+C++g++ dg +C FUN_001023-T1 367 DIDECKSWR-SC-DLHASCTNTKGSYKCRCNPGFQ--GDGISC 405 9******99.**.7********************9..666555 PP == domain 9 score: 38.4 bits; conditional E-value: 7.1e-13 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D dEC+ g h+C ++n++CvN +Gs++C+C++gy+ +gk C FUN_001023-T1 407 DYDECEAGDHDC-NKNAKCVNRKGSYSCSCNKGYR--GNGKDC 446 89**********.8*********************..666666 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 1.6 8.7e-07 0.0019 2 24 .] 105 125 .. 104 125 .. 0.95 2 ! 31.2 0.6 9.6e-11 2e-07 1 24 [] 144 165 .. 144 165 .. 0.98 3 ! 31.5 3.8 7.7e-11 1.6e-07 2 24 .] 186 206 .. 185 206 .. 0.97 4 ! 35.5 1.7 4.2e-12 9e-09 2 24 .] 227 247 .. 226 247 .. 0.97 5 ! 27.2 3.0 1.7e-09 3.6e-06 1 24 [] 267 288 .. 267 288 .. 0.96 6 ! 35.2 3.1 5.5e-12 1.2e-08 1 24 [] 308 329 .. 308 329 .. 0.99 7 ! 18.9 7.9 6.5e-07 0.0014 1 24 [] 349 370 .. 349 370 .. 0.99 8 ! 26.3 5.4 3.2e-09 6.9e-06 1 24 [] 389 410 .. 389 410 .. 0.97 9 ! 18.4 6.8 9.9e-07 0.0021 1 20 [. 430 447 .. 430 447 .. 0.96 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 8.7e-07 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 tC+C+ GY g+G C D +E FUN_001023-T1 105 HTCQCNVGYH--GNGSVCYDLNE 125 59********..9*********9 PP == domain 2 score: 31.2 bits; conditional E-value: 9.6e-11 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 S+ C+C +G++ g+G+tC D+DE FUN_001023-T1 144 SFNCECLQGFQ--GNGTTCLDVDE 165 899********..9*********9 PP == domain 3 score: 31.5 bits; conditional E-value: 7.7e-11 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 Y CsC +G++ gDG+tC D+DE FUN_001023-T1 186 YNCSCFSGFE--GDGKTCRDVDE 206 99********..**********9 PP == domain 4 score: 35.5 bits; conditional E-value: 4.2e-12 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 ++C+C +GY+ gDGr+C+D++E FUN_001023-T1 227 FHCTCLNGYQ--GDGRNCTDVNE 247 9*********..**********9 PP == domain 5 score: 27.2 bits; conditional E-value: 1.7e-09 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ gDG C DIDE FUN_001023-T1 267 SYGCTCHQGFE--GDGWACRDIDE 288 788********..**********9 PP == domain 6 score: 35.2 bits; conditional E-value: 5.5e-12 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY+CsC +GY+ gDG+tC DI+E FUN_001023-T1 308 SYVCSCSRGYK--GDGHTCMDINE 329 9**********..**********9 PP == domain 7 score: 18.9 bits; conditional E-value: 6.5e-07 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C C +GY+ g+G C DIDE FUN_001023-T1 349 SYSCRCVEGYR--GNGEYCYDIDE 370 9**********..9*********9 PP == domain 8 score: 26.3 bits; conditional E-value: 3.2e-09 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY+C C+pG++ gDG +CvD DE FUN_001023-T1 389 SYKCRCNPGFQ--GDGISCVDYDE 410 9**********..9*******998 PP == domain 9 score: 18.4 bits; conditional E-value: 9.9e-07 cEGF 1 SYtCsCppGYtLagDGrtCv 20 SY CsC++GY+ g+G+ C+ FUN_001023-T1 430 SYSCSCNKGYR--GNGKDCK 447 9**********..9*****5 PP >> EGF_MSP1_1 MSP1 EGF domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 8.8 0.00015 0.33 2 36 .. 85 120 .. 84 121 .. 0.92 2 ! 18.1 9.0 1.4e-06 0.0029 1 37 [] 125 161 .. 125 161 .. 0.95 3 ! 13.0 8.6 5.2e-05 0.11 2 36 .. 166 201 .. 165 202 .. 0.92 4 ! 13.1 7.1 4.9e-05 0.1 6 36 .. 213 242 .. 206 243 .. 0.92 5 ! 11.5 7.7 0.00015 0.31 5 36 .. 253 283 .. 247 284 .. 0.89 6 ! 19.0 5.6 6.8e-07 0.0015 5 37 .] 294 325 .. 288 325 .. 0.87 7 ! 16.6 9.1 3.8e-06 0.0082 2 36 .. 330 365 .. 329 366 .. 0.87 8 ! 29.6 6.6 3.5e-10 7.4e-07 1 37 [] 370 406 .. 370 406 .. 0.96 9 ! 21.5 12.2 1.1e-07 0.00024 3 36 .. 414 446 .. 410 447 .. 0.91 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00015 EGF_MSP1_1 2 Cvk.vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C++ + c+ NA+C + C C+ gy +g+ C FUN_001023-T1 85 CRNkTLCDVNAACKAIDHNHHTCQCNVGYHGNGSVC 120 888789*******999989**************999 PP == domain 2 score: 18.1 bits; conditional E-value: 1.4e-06 EGF_MSP1_1 1 eCvk.vkcPaNAkCvrhadgreECrCllgykkeggkCv 37 eC++ +c +NA C + + g+ C Cl g+ +g +C+ FUN_001023-T1 125 ECLGrHNCSENARCKNTT-GSFNCECLQGFQGNGTTCL 161 6999789***********.******************6 PP == domain 3 score: 13.0 bits; conditional E-value: 5.2e-05 EGF_MSP1_1 2 Cvk..vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C + +c ++A C + g + C C g+ +g +C FUN_001023-T1 166 CSDnlHNCSQHAYCNNTI-GAYNCSCFSGFEGDGKTC 201 7776689***********.****************** PP == domain 4 score: 13.1 bits; conditional E-value: 4.9e-05 EGF_MSP1_1 6 kcPaNAkCvrhadgreECrCllgykkeggkC 36 c ++A+C + g C Cl gy +g C FUN_001023-T1 213 RCNKHAFCSNTE-GAFHCTCLNGYQGDGRNC 242 7*********99.***************999 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00015 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g++ C C g+ +g C FUN_001023-T1 253 HNCSVHADCTNSN-GSYGCTCHQGFEGDGWAC 283 58999*******9.***********9999777 PP == domain 6 score: 19.0 bits; conditional E-value: 6.8e-07 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkCv 37 +c +A C + + g++ C C gyk +g +C+ FUN_001023-T1 294 DNCGTHASCQNID-GSYVCSCSRGYKGDGHTCM 325 5899*****6665.******************5 PP == domain 7 score: 16.6 bits; conditional E-value: 3.8e-06 EGF_MSP1_1 2 Cvk..vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C++ c aN+ C++ g++ CrC gy +g+ C FUN_001023-T1 330 CREgtHGCRANSRCINTP-GSYSCRCVEGYRGNGEYC 365 555445699*********.****************99 PP == domain 8 score: 29.6 bits; conditional E-value: 3.5e-10 EGF_MSP1_1 1 eCvk.vkcPaNAkCvrhadgreECrCllgykkeggkCv 37 eC + ++c+ +A C + g++ CrC++g+ +g Cv FUN_001023-T1 370 ECKSwRSCDLHASCTNTK-GSYKCRCNPGFQGDGISCV 406 79999*************.***************9997 PP == domain 9 score: 21.5 bits; conditional E-value: 1.1e-07 EGF_MSP1_1 3 vkvkcPaNAkCvrhadgreECrCllgykkeggkC 36 ++ +c +NAkCv+ g++ C C+ gy +g C FUN_001023-T1 414 GDHDCNKNAKCVNRK-GSYSCSCNKGYRGNGKDC 446 4689***********.***************999 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 7.6 6.5e-05 0.14 1 31 [. 85 116 .. 85 117 .. 0.88 2 ! 20.2 7.0 3.6e-07 0.00076 4 31 .. 130 156 .. 120 157 .. 0.91 3 ! 16.0 9.2 7.1e-06 0.015 1 31 [. 166 197 .. 166 198 .. 0.91 4 ! 19.7 6.8 5e-07 0.0011 4 31 .. 212 238 .. 207 239 .. 0.92 5 ! 7.7 11.4 0.0029 6.2 1 31 [. 248 279 .. 242 280 .. 0.88 6 ! 16.7 6.2 4.5e-06 0.0096 4 31 .. 294 320 .. 289 321 .. 0.89 7 ! 20.7 9.3 2.5e-07 0.00053 1 31 [. 330 361 .. 330 362 .. 0.88 8 ! 17.0 6.2 3.6e-06 0.0076 6 31 .. 377 401 .. 371 402 .. 0.87 9 ! 20.9 8.7 2.1e-07 0.00044 4 31 .. 416 442 .. 411 443 .. 0.86 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 6.5e-05 EGF 1 Cspnp..CsngGtCvdtprggytCiCpeGytGk 31 C n+ C+ ++ C +++tC+C +Gy+G+ FUN_001023-T1 85 CR-NKtlCDVNAACKAIDHNHHTCQCNVGYHGN 116 55.4458*******9999**************7 PP == domain 2 score: 20.2 bits; conditional E-value: 3.6e-07 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs +++C +t g+++C+C +G+ G+ FUN_001023-T1 130 HNCSENARCKNTT-GSFNCECLQGFQGN 156 78***********.************97 PP == domain 3 score: 16.0 bits; conditional E-value: 7.1e-06 EGF 1 Csp..npCsngGtCvdtprggytCiCpeGytGk 31 Cs+ ++Cs ++ C +t g y+C C G+ G+ FUN_001023-T1 166 CSDnlHNCSQHAYCNNTI-GAYNCSCFSGFEGD 197 7765588***********.************97 PP == domain 4 score: 19.7 bits; conditional E-value: 5e-07 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++C+ +++C +t+ g ++C+C +Gy G+ FUN_001023-T1 212 HRCNKHAFCSNTE-GAFHCTCLNGYQGD 238 67***********.************97 PP == domain 5 score: 7.7 bits; conditional E-value: 0.0029 EGF 1 Csp..npCsngGtCvdtprggytCiCpeGytGk 31 C+ ++Cs ++ C ++ g+y C+C +G+ G+ FUN_001023-T1 248 CNMeiHNCSVHADCTNSN-GSYGCTCHQGFEGD 279 5555599*******7777.************97 PP == domain 6 score: 16.7 bits; conditional E-value: 4.5e-06 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++C ++ C + g+y C C+ Gy+G+ FUN_001023-T1 294 DNCGTHASCQNID-GSYVCSCSRGYKGD 320 78***********.*************7 PP == domain 7 score: 20.7 bits; conditional E-value: 2.5e-07 EGF 1 Cspnp..CsngGtCvdtprggytCiCpeGytGk 31 C +++ C + +C++tp g+y+C+C eGy G+ FUN_001023-T1 330 CREGThgCRANSRCINTP-GSYSCRCVEGYRGN 361 666555699*********.************97 PP == domain 8 score: 17.0 bits; conditional E-value: 3.6e-06 EGF 6 CsngGtCvdtprggytCiCpeGytGk 31 C+ ++ C +t g+y+C+C +G+ G+ FUN_001023-T1 377 CDLHASCTNTK-GSYKCRCNPGFQGD 401 88899******.************97 PP == domain 9 score: 20.9 bits; conditional E-value: 2.1e-07 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 + C+ +++Cv+ g+y+C C Gy G+ FUN_001023-T1 416 HDCNKNAKCVNRK-GSYSCSCNKGYRGN 442 55***********.************97 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.5 0.00022 0.48 10 22 .] 101 113 .. 94 113 .. 0.81 2 ? -3.2 0.7 9.1 1.9e+04 3 10 .. 116 123 .. 115 126 .. 0.74 3 ! 18.4 3.2 1.5e-06 0.0032 1 22 [] 132 153 .. 132 153 .. 0.97 4 ? -3.0 0.4 7.8 1.7e+04 4 9 .. 156 162 .. 154 166 .. 0.63 5 ! 10.8 6.8 0.00036 0.78 1 21 [. 173 193 .. 173 194 .. 0.91 6 ! 12.6 5.0 9.5e-05 0.2 1 22 [] 214 235 .. 214 235 .. 0.98 7 ! 6.4 7.0 0.0089 19 4 22 .] 258 276 .. 255 276 .. 0.91 8 ! 13.5 6.1 5.1e-05 0.11 1 22 [] 296 317 .. 296 317 .. 0.97 9 ! 18.9 4.1 1e-06 0.0022 1 22 [] 337 358 .. 337 358 .. 0.91 10 ! 22.9 4.2 5.7e-08 0.00012 1 22 [] 377 398 .. 377 398 .. 0.93 11 ? -3.0 0.2 7.9 1.7e+04 6 16 .. 404 411 .. 401 412 .. 0.63 12 ! 16.2 6.3 7e-06 0.015 1 22 [] 418 439 .. 418 439 .. 0.98 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00022 hEGF 10 gvngykCqCppGy 22 +n+++CqC+ Gy FUN_001023-T1 101 DHNHHTCQCNVGY 113 45888*******9 PP == domain 2 score: -3.2 bits; conditional E-value: 9.1 hEGF 3 NGGtCvdg 10 NG C d+ FUN_001023-T1 116 NGSVCYDL 123 88899876 PP == domain 3 score: 18.4 bits; conditional E-value: 1.5e-06 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ +++C ++++++ C+C +G+ FUN_001023-T1 132 CSENARCKNTTGSFNCECLQGF 153 9999*****************9 PP == domain 4 score: -3.0 bits; conditional E-value: 7.8 hEGF 4 GG.tCvd 9 +G tC d FUN_001023-T1 156 NGtTCLD 162 4558985 PP == domain 5 score: 10.8 bits; conditional E-value: 0.00036 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C++++ C+++++ y C+C +G FUN_001023-T1 173 CSQHAYCNNTIGAYNCSCFSG 193 ******************555 PP == domain 6 score: 12.6 bits; conditional E-value: 9.5e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++ C+++ + + C C Gy FUN_001023-T1 214 CNKHAFCSNTEGAFHCTCLNGY 235 9********************9 PP == domain 7 score: 6.4 bits; conditional E-value: 0.0089 hEGF 4 GGtCvdgvngykCqCppGy 22 ++ C++ +++y C C +G+ FUN_001023-T1 258 HADCTNSNGSYGCTCHQGF 276 789***************9 PP == domain 8 score: 13.5 bits; conditional E-value: 5.1e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C +++C++ ++y+C+C Gy FUN_001023-T1 296 CGTHASCQNIDGSYVCSCSRGY 317 999******************9 PP == domain 9 score: 18.9 bits; conditional E-value: 1e-06 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ + +C++++++y+C+C +Gy FUN_001023-T1 337 CRANSRCINTPGSYSCRCVEGY 358 666779***************9 PP == domain 10 score: 22.9 bits; conditional E-value: 5.7e-08 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C +++C+++ ++ykC+C+pG+ FUN_001023-T1 377 CDLHASCTNTKGSYKCRCNPGF 398 66699****************9 PP == domain 11 score: -3.0 bits; conditional E-value: 7.9 hEGF 6 tCvdgvngykC 16 +Cv + +C FUN_001023-T1 404 SCV---DYDEC 411 899...55556 PP == domain 12 score: 16.2 bits; conditional E-value: 7e-06 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ +++Cv++ ++y+C+C+ Gy FUN_001023-T1 418 CNKNAKCVNRKGSYSCSCNKGY 439 9********************9 PP >> ADGRF3_N ADGRF3-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 10.5 0.00017 0.37 3 44 .. 96 138 .. 94 140 .. 0.85 2 ! 15.5 8.0 1.1e-05 0.024 3 42 .. 137 173 .. 135 179 .. 0.85 3 ! 8.9 5.8 0.0014 2.9 4 42 .. 179 214 .. 176 220 .. 0.84 4 ! 13.2 8.6 5.8e-05 0.12 4 42 .. 220 255 .. 217 261 .. 0.86 5 ? 5.8 8.9 0.012 26 3 42 .. 260 296 .. 258 305 .. 0.79 6 ! 9.3 8.3 0.001 2.2 4 45 .. 302 344 .. 298 347 .. 0.78 7 ! 7.9 10.6 0.0028 5.9 4 38 .. 343 376 .. 340 385 .. 0.78 8 ! 11.7 8.1 0.00018 0.38 3 46 .. 382 426 .. 380 428 .. 0.81 9 ! 9.1 3.4 0.0011 2.4 3 29 .. 423 448 .. 421 453 .. 0.82 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00017 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqess.eeqsCsC 44 +C++ +++ +C+C+ gY+ n svC+ ++C +++ +++ +C FUN_001023-T1 96 ACKAIDHNHHTCQCNVGYHGNGSVCYDLNECLGRHnCSENARC 138 699999999**********************999833555555 PP == domain 2 score: 15.5 bits; conditional E-value: 1.1e-05 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 C+++ +g+++C+C++g+q n ++C ++C+++ ++C FUN_001023-T1 137 RCKNT-TGSFNCECLQGFQGNGTTCLDVDECSDNL--HNC 173 58887.799***********************886..444 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0014 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 Cn++ g ++C+C sg++ + ++C ++C+ ++C FUN_001023-T1 179 CNNTI-GAYNCSCFSGFEGDGKTCRDVDECKVML--HRC 214 99985.88**********************9765..444 PP == domain 4 score: 13.2 bits; conditional E-value: 5.8e-05 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 C+++ +g ++C+C++gYq + + C+ ++C+ + ++C FUN_001023-T1 220 CSNT-EGAFHCTCLNGYQGDGRNCTDVNECNMEI--HNC 255 8777.688**********************9887..555 PP == domain 5 score: 5.8 bits; conditional E-value: 0.012 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s ng++ C+C++g++ + +C ++C+ + ++C FUN_001023-T1 260 DCTNS-NGSYGCTCHQGFEGDGWACRDIDECKMRV--DNC 296 68776.799**********************9877..333 PP == domain 6 score: 9.3 bits; conditional E-value: 0.001 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqess..eeqsCsCl 45 C++ +g++ C+C gY+ + ++C ++C+e + + + +C+ FUN_001023-T1 302 CQN-IDGSYVCSCSRGYKGDGHTCMDINECREGThgCRANSRCI 344 665.4799**********************98762335555666 PP == domain 7 score: 7.9 bits; conditional E-value: 0.0028 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesse 38 C ++ g+++C+C +gY+ n + C+ ++C++ ++ FUN_001023-T1 343 CINT-PGSYSCRCVEGYRGNGEYCYDIDECKSWRS 376 5555.5889*********************98873 PP == domain 8 score: 11.7 bits; conditional E-value: 0.00018 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqess..eeqsCsCli 46 C+++ +g+++C+C++g+q + C y++C+ + +++ +C++ FUN_001023-T1 382 SCTNT-KGSYKCRCNPGFQGDGISCVDYDECEAGDhdCNKNAKCVN 426 58887.588**********************966522477777775 PP == domain 9 score: 9.1 bits; conditional E-value: 0.0011 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCsk 29 +C ++ +g+++C+C++gY+ n + C+ FUN_001023-T1 423 KCVNR-KGSYSCSCNKGYRGNGKDCKV 448 57665.699**********99999975 PP >> FXa_inhibition Coagulation Factor Xa inhibitory site # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 8.1 0.34 7.2e+02 8 28 .. 91 114 .. 85 120 .. 0.77 2 ! 8.0 10.5 0.0022 4.6 6 36 .] 130 160 .. 126 160 .. 0.87 3 ! 16.8 12.5 3.9e-06 0.0082 1 36 [] 166 201 .. 166 201 .. 0.94 4 ! 13.3 9.5 4.5e-05 0.097 1 36 [] 207 242 .. 207 242 .. 0.89 5 ! 6.7 10.4 0.0053 11 1 28 [. 248 277 .. 248 283 .. 0.80 6 ! 11.5 12.0 0.00017 0.36 3 36 .] 293 324 .. 289 324 .. 0.84 7 ! 16.7 11.9 4e-06 0.0086 1 28 [. 330 359 .. 330 365 .. 0.89 8 ! 14.0 5.6 2.8e-05 0.06 8 36 .] 377 405 .. 374 405 .. 0.84 9 ! 10.4 13.8 0.00037 0.8 1 36 [] 411 446 .. 411 446 .. 0.86 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.34 FXa_inhibition 8 Cs..hlClnt.pggytCsCpeGye 28 C+ C++ + +tC+C Gy+ FUN_001023-T1 91 CDvnAACKAIdHNHHTCQCNVGYH 114 66556799995568*********7 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0022 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGyeLsdDgktC 36 + Cs C+nt g++ C C +G++ +g+tC FUN_001023-T1 130 HNCSenARCKNTTGSFNCECLQGFQ--GNGTTC 160 56987779***************99..778888 PP == domain 3 score: 16.8 bits; conditional E-value: 3.9e-06 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 Cs+n + Cs +C nt g y CsC +G+e DgktC FUN_001023-T1 166 CSDNLHNCSqhAYCNNTIGAYNCSCFSGFE--GDGKTC 201 *********6559****************9..99**** PP == domain 4 score: 13.3 bits; conditional E-value: 4.5e-05 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 C+v + C +C+nt g ++C+C +Gy+ Dg++C FUN_001023-T1 207 CKVMLHRCNkhAFCSNTEGAFHCTCLNGYQ--GDGRNC 242 666667898867*****************9..999999 PP == domain 5 score: 6.7 bits; conditional E-value: 0.0053 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+ + + Cs C+n+ g+y C+C++G+e FUN_001023-T1 248 CNMEIHNCSvhADCTNSNGSYGCTCHQGFE 277 5556678998445***************98 PP == domain 6 score: 11.5 bits; conditional E-value: 0.00017 FXa_inhibition 3 vnNggCshlClntpggytCsCpeGyeLsdDgktC 36 v+N+g C n g+y+CsC Gy+ Dg+tC FUN_001023-T1 293 VDNCGTHASCQNIDGSYVCSCSRGYK--GDGHTC 324 456666689*****************..999999 PP == domain 7 score: 16.7 bits; conditional E-value: 4e-06 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C++ +gC C+ntpg+y+C+C eGy+ FUN_001023-T1 330 CREGTHGCRanSRCINTPGSYSCRCVEGYR 359 899999**97789****************8 PP == domain 8 score: 14.0 bits; conditional E-value: 2.8e-05 FXa_inhibition 8 Cs..hlClntpggytCsCpeGyeLsdDgktC 36 C+ C+nt g+y+C+C +G++ Dg +C FUN_001023-T1 377 CDlhASCTNTKGSYKCRCNPGFQ--GDGISC 405 555456***************99..777777 PP == domain 9 score: 10.4 bits; conditional E-value: 0.00037 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 C+ + C C+n+ g+y+CsC +Gy+ +gk C FUN_001023-T1 411 CEAGDHDCNknAKCVNRKGSYSCSCNKGYR--GNGKDC 446 8888899997778****************9..666666 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 6.6 1.4e+04 11 18 .. 38 44 .. 37 48 .. 0.67 2 ! 12.1 8.9 0.0001 0.22 1 40 [. 84 120 .. 84 121 .. 0.90 3 ! 9.7 7.1 0.00061 1.3 5 40 .. 130 160 .. 125 161 .. 0.88 4 ! 8.7 7.9 0.0012 2.5 2 40 .. 166 201 .. 165 202 .. 0.90 5 ? 4.7 5.6 0.021 45 6 40 .. 213 242 .. 206 243 .. 0.77 6 ? 2.9 9.1 0.079 1.7e+02 6 32 .. 254 276 .. 241 284 .. 0.88 7 ! 11.2 7.7 0.0002 0.43 6 40 .. 295 324 .. 288 325 .. 0.91 8 ! 11.1 6.7 0.00022 0.46 7 38 .. 337 363 .. 329 366 .. 0.85 9 ! 12.5 5.3 8.1e-05 0.17 7 33 .. 377 399 .. 370 406 .. 0.81 10 ! 9.4 12.7 0.00073 1.5 6 40 .. 417 446 .. 410 447 .. 0.90 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 6.6 Plasmod_Pvs28 11 gkCklglp 18 + Ck++ + FUN_001023-T1 38 ALCKNV-A 44 569998.4 PP == domain 2 score: 12.1 bits; conditional E-value: 0.0001 Plasmod_Pvs28 1 kCqlKa.CgengkCklglpqnsnhykCsCniGyvllnenkC 40 +C +K+ C +n+ Ck nh++C+Cn Gy n+++C FUN_001023-T1 84 DCRNKTlCDVNAACKAI---DHNHHTCQCNVGYH-GNGSVC 120 5899644********99...89***********9.999999 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00061 Plasmod_Pvs28 5 KaCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +C en+ Ck++ +++ C C G+ n+ +C FUN_001023-T1 130 HNCSENARCKNT----TGSFNCECLQGFQ-GNGTTC 160 58**********....***********99.888888 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0012 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCniGyvllnenkC 40 C+ +C ++++C ++ ++y CsC G+ ++++C FUN_001023-T1 166 CSDnlHNCSQHAYCNNT----IGAYNCSCFSGFE-GDGKTC 201 6666679**********....************9.999999 PP == domain 5 score: 4.7 bits; conditional E-value: 0.021 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 C ++ C ++ ++++ C C +Gy ++ C FUN_001023-T1 213 RCNKHAFCSNT----EGAFHCTCLNGYQ-GDGRNC 242 47789******....************7.555555 PP == domain 6 score: 2.9 bits; conditional E-value: 0.079 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGy 32 +C +++ C++ +++y C C G+ FUN_001023-T1 254 NCSVHADCTNS----NGSYGCTCHQGF 276 7**********....********9998 PP == domain 7 score: 11.2 bits; conditional E-value: 0.0002 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +Cg ++ C + +++y+CsC Gy+ ++ +C FUN_001023-T1 295 NCGTHASCQNI----DGSYVCSCSRGYK-GDGHTC 324 6**********....*************.999998 PP == domain 8 score: 11.1 bits; conditional E-value: 0.00022 Plasmod_Pvs28 7 CgengkCklglpqnsnhykCsCniGyvllnen 38 C +n C+++ +++y C C +Gy n++ FUN_001023-T1 337 CRANSRCINT----PGSYSCRCVEGYR-GNGE 363 999*******....************7.6665 PP == domain 9 score: 12.5 bits; conditional E-value: 8.1e-05 Plasmod_Pvs28 7 CgengkCklglpqnsnhykCsCniGyv 33 C ++ C+++ ++ykC Cn+G+ FUN_001023-T1 377 CDLHASCTNT----KGSYKCRCNPGFQ 399 778899****....***********96 PP == domain 10 score: 9.4 bits; conditional E-value: 0.00073 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +C n+kC + ++y CsCn+Gy n++ C FUN_001023-T1 417 DCNKNAKCVNR----KGSYSCSCNKGYR-GNGKDC 446 6999*******....************9.888888 PP >> EGF_TEN Teneurin EGF domain [No individual domains that satisfy reporting thresholds (although complete target did)] >> EGF_Mua-3 Transmembrane cell adhesion receptor mua-3-like, EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 5.6 0.0008 1.7 1 29 [. 85 113 .. 85 115 .. 0.91 2 ? 5.9 7.9 0.0086 18 5 29 .. 130 153 .. 120 155 .. 0.88 3 ? -0.4 7.2 0.79 1.7e+03 1 29 [. 166 194 .. 160 197 .. 0.86 4 ? 0.4 9.1 0.46 9.8e+02 7 29 .. 214 235 .. 201 249 .. 0.84 5 ? 0.7 9.0 0.37 7.9e+02 4 29 .. 252 276 .. 242 278 .. 0.77 6 ? 8.7 3.8 0.0011 2.4 4 29 .. 293 317 .. 283 320 .. 0.91 7 ? 11.4 3.1 0.00017 0.37 7 29 .. 337 358 .. 324 360 .. 0.89 8 ? 9.1 3.9 0.00087 1.9 7 29 .. 377 398 .. 371 400 .. 0.86 9 ? 13.0 2.2 5.5e-05 0.12 7 29 .. 418 439 .. 415 461 .. 0.88 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0008 EGF_Mua-3 1 CsDvnfCPaNttCvNleeqqAeCeCneGf 29 C+ C +N++C+ ++++ +C+Cn G+ FUN_001023-T1 85 CRNKTLCDVNAACKAIDHNHHTCQCNVGY 113 666778***********9**********9 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0086 EGF_Mua-3 5 nfCPaNttCvNleeqqAeCeCneGf 29 + C N+ C+N+ +CeC +Gf FUN_001023-T1 130 HNCSENARCKNTT-GSFNCECLQGF 153 5699********9.69********9 PP == domain 3 score: -0.4 bits; conditional E-value: 0.79 EGF_Mua-3 1 CsD.vnfCPaNttCvNleeqqAeCeCneGf 29 CsD ++ C + + C N+ +C+C +Gf FUN_001023-T1 166 CSDnLHNCSQHAYCNNTI-GAYNCSCFSGF 194 7775678999999***98.5889******9 PP == domain 4 score: 0.4 bits; conditional E-value: 0.46 EGF_Mua-3 7 CPaNttCvNleeqqAeCeCneGf 29 C + + C N+e +C+C +G+ FUN_001023-T1 214 CNKHAFCSNTE-GAFHCTCLNGY 235 777889****9.588*******9 PP == domain 5 score: 0.7 bits; conditional E-value: 0.37 EGF_Mua-3 4 vnfCPaNttCvNleeqqAeCeCneGf 29 ++ C + + C N + C+C++Gf FUN_001023-T1 252 IHNCSVHADCTNSN-GSYGCTCHQGF 276 455777789***98.6999******9 PP == domain 6 score: 8.7 bits; conditional E-value: 0.0011 EGF_Mua-3 4 vnfCPaNttCvNleeqqAeCeCneGf 29 v+ C + ++C+N++ C+C++G+ FUN_001023-T1 293 VDNCGTHASCQNID-GSYVCSCSRGY 317 778999*******9.699*******9 PP == domain 7 score: 11.4 bits; conditional E-value: 0.00017 EGF_Mua-3 7 CPaNttCvNleeqqAeCeCneGf 29 C aN+ C+N++ +C+C eG+ FUN_001023-T1 337 CRANSRCINTP-GSYSCRCVEGY 358 99*********.699*******9 PP == domain 8 score: 9.1 bits; conditional E-value: 0.00087 EGF_Mua-3 7 CPaNttCvNleeqqAeCeCneGf 29 C ++C N++ +C+Cn+Gf FUN_001023-T1 377 CDLHASCTNTK-GSYKCRCNPGF 398 88899*****9.69********9 PP == domain 9 score: 13.0 bits; conditional E-value: 5.5e-05 EGF_Mua-3 7 CPaNttCvNleeqqAeCeCneGf 29 C +N+ CvN + +C+Cn+G+ FUN_001023-T1 418 CNKNAKCVNRK-GSYSCSCNKGY 439 999******99.699*******9 PP >> RecD_N RecBCD enzyme subunit RecD, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.7 0.32 6.8e+02 31 31 .. 147 147 .. 107 173 .. 0.55 2 ? 1.7 0.1 0.22 4.6e+02 38 54 .. 154 170 .. 144 187 .. 0.77 3 ? 4.0 0.1 0.043 92 38 52 .. 318 332 .. 308 344 .. 0.80 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.32 RecD_N 31 a 31 + FUN_001023-T1 147 C 147 1 PP == domain 2 score: 1.7 bits; conditional E-value: 0.22 RecD_N 38 lgrGhvCLdLaelaeea 54 g+G +CLd++e++++ FUN_001023-T1 154 QGNGTTCLDVDECSDNL 170 699*********98874 PP == domain 3 score: 4.0 bits; conditional E-value: 0.043 RecD_N 38 lgrGhvCLdLaelae 52 g+Gh+C+d++e++e FUN_001023-T1 318 KGDGHTCMDINECRE 332 599*******99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (476 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1297 (0.0507731); expected 510.9 (0.02) Passed bias filter: 570 (0.0223136); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4566.24 // Query: FUN_001024-T1 [L=476] Description: FUN_001024 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-91 299.3 163.3 9e-12 45.5 10.8 9.2 9 EGF_3 EGF domain 1.5e-72 240.1 155.0 2e-10 41.2 11.3 9.3 9 EGF_CA Calcium-binding EGF domain 1.5e-57 191.5 77.3 1.3e-07 31.8 2.2 9.7 9 cEGF Complement Clr-like EGF-like 5e-26 91.1 136.6 0.00013 22.7 7.2 10.0 9 EGF EGF-like domain 2.6e-23 82.2 129.2 8.2e-05 23.0 6.2 9.4 9 EGF_MSP1_1 MSP1 EGF domain 1 1.6e-09 38.3 140.6 0.049 14.3 4.4 9.5 9 FXa_inhibition Coagulation Factor Xa inhibitory site 1.9e-09 38.3 119.4 0.049 14.5 5.8 9.6 9 ADGRF3_N ADGRF3-like, N-terminal domain 1.4e-08 35.3 136.8 0.002 19.0 4.2 13.0 15 hEGF Human growth factor-like EGF 7.4e-07 29.6 123.5 0.033 14.7 6.6 9.9 9 Plasmod_Pvs28 Pvs28 EGF domain 0.0013 18.9 130.1 2.6e+04 -13.2 130.1 2.6 1 EGF_TEN Teneurin EGF domain Domain annotation for each model (and alignments): >> EGF_3 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 11.0 4.3e-09 1.1e-05 6 36 .] 83 114 .. 79 114 .. 0.91 2 ! 40.4 9.8 1.4e-13 3.5e-10 4 36 .] 122 154 .. 121 154 .. 0.97 3 ! 38.5 13.8 5.4e-13 1.4e-09 1 36 [] 160 195 .. 160 195 .. 0.99 4 ! 38.9 10.5 4e-13 1e-09 1 36 [] 201 236 .. 201 236 .. 0.99 5 ! 39.2 10.6 3.2e-13 8.3e-10 1 36 [] 242 277 .. 242 277 .. 0.99 6 ! 45.5 10.8 3.5e-15 9e-12 1 36 [] 283 318 .. 283 318 .. 0.99 7 ! 42.5 10.9 3e-14 7.6e-11 1 36 [] 324 359 .. 324 359 .. 0.99 8 ! 36.7 9.5 1.9e-12 4.9e-09 1 36 [] 365 400 .. 365 400 .. 0.99 9 ! 43.2 12.4 1.9e-14 4.9e-11 1 36 [] 406 441 .. 406 441 .. 0.98 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 4.3e-09 EGF_3 6 ggChanAtCtnteg.sfkCtCkagytGdGvtC 36 + C++nA C+ ++ ++C+C+ gy+G+G +C FUN_001024-T1 83 TLCDVNAVCKAIDHsHHTCQCNVGYHGNGSVC 114 48************99**************** PP == domain 2 score: 40.4 bits; conditional E-value: 1.4e-13 EGF_3 4 nnggChanAtCtntegsfkCtCkagytGdGvtC 36 ++++C++nA+C+nt gsf+C C +g++G+G tC FUN_001024-T1 122 GSHNCGDNARCKNTMGSFNCDCLQGFQGNGMTC 154 689****************************** PP == domain 3 score: 38.5 bits; conditional E-value: 5.4e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 Cs+ ++C+++A C+nt g ++CtC +g++GdG+tC FUN_001024-T1 160 CSDSVDNCSQHAYCNNTLGAYNCTCFSGFEGDGKTC 195 9*********************************** PP == domain 4 score: 38.9 bits; conditional E-value: 4e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C++ ++Ch++A C n+eg ++C+C +gy+GdG++C FUN_001024-T1 201 CKVMLHQCHKHAFCINNEGAYNCSCLNGYQGDGWNC 236 99999******************************* PP == domain 5 score: 39.2 bits; conditional E-value: 3.2e-13 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C++ A+Ctn gs++CtC++g++GdG++C FUN_001024-T1 242 CKLGIHNCSEYADCTNSFGSHECTCHEGFEGDGWVC 277 999********************************* PP == domain 6 score: 45.5 bits; conditional E-value: 3.5e-15 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+++A+Ctn gs++CtC++g++GdG++C FUN_001024-T1 283 CERGIHNCSEHADCTNSIGSYRCTCHQGFEGDGWVC 318 9*********************************** PP == domain 7 score: 42.5 bits; conditional E-value: 3e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+ + ++C+++A+Ctn gs+ CtC++g++GdG+ C FUN_001024-T1 324 CKRRIHNCSVHADCTNSIGSYGCTCHQGFEGDGWAC 359 9**********************************9 PP == domain 8 score: 36.7 bits; conditional E-value: 1.9e-12 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C+++ ++C+ +A Ctn+ g f+C+Ck+g++G+G+ C FUN_001024-T1 365 CKVKVDNCSRHAFCTNNVGAFSCECKKGFEGNGWLC 400 99********************************99 PP == domain 9 score: 43.2 bits; conditional E-value: 1.9e-14 EGF_3 1 CsknnggChanAtCtntegsfkCtCkagytGdGvtC 36 C ++++C+ +A C+n++gs++C+C++gy+GdG+tC FUN_001024-T1 406 CWRGTHNCDTHASCQNIDGSYVCSCSSGYKGDGRTC 441 8899******************************** PP >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 6.7 0.02 51 5 43 .] 79 114 .. 77 114 .. 0.82 2 ! 32.9 10.5 3.2e-11 8.1e-08 1 43 [] 116 154 .. 116 154 .. 0.90 3 ! 32.7 13.1 3.5e-11 9e-08 1 43 [] 156 195 .. 156 195 .. 0.97 4 ! 36.8 9.6 1.9e-12 4.8e-09 1 43 [] 197 236 .. 197 236 .. 0.94 5 ! 32.1 10.9 5.5e-11 1.4e-07 1 40 [. 238 274 .. 238 277 .. 0.92 6 ! 40.1 10.5 1.7e-13 4.3e-10 1 40 [. 279 315 .. 279 318 .. 0.92 7 ! 36.3 9.4 2.6e-12 6.6e-09 1 43 [] 320 359 .. 320 359 .. 0.92 8 ! 34.6 9.0 9.4e-12 2.4e-08 1 35 [. 361 394 .. 361 400 .. 0.93 9 ! 41.2 11.3 7.8e-14 2e-10 1 43 [] 402 441 .. 402 441 .. 0.95 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.02 EGF_CA 5 CaegthnCpdentvCvNteGsf.eCvCeegyennedgkkC 43 C+ t C d n+vC + s +C+C+ gy+ +g+ C FUN_001024-T1 79 CRHKT-LC-DVNAVCKAIDHSHhTCQCNVGYH--GNGSVC 114 88766.9*.7*********99637*******9..555555 PP == domain 2 score: 32.9 bits; conditional E-value: 3.2e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 D++EC +hnC +n+ C Nt Gsf+C C +g++ +g +C FUN_001024-T1 116 DLNECLG-SHNC-GDNARCKNTMGSFNCDCLQGFQ--GNGMTC 154 9****98.78**.79********************..666666 PP == domain 3 score: 32.7 bits; conditional E-value: 3.5e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 DvdEC + +nC ++++ C+Nt G ++C+C +g+e dgk+C FUN_001024-T1 156 DVDECSDSVDNC-SQHAYCNNTLGAYNCTCFSGFE--GDGKTC 195 9***********.8*********************..999999 PP == domain 4 score: 36.8 bits; conditional E-value: 1.9e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 DvdEC+ h+C ++++ C+N+eG ++C+C +gy+ dg +C FUN_001024-T1 197 DVDECKVMLHQC-HKHAFCINNEGAYNCSCLNGYQ--GDGWNC 236 9***********.9*********************..777777 PP == domain 5 score: 32.1 bits; conditional E-value: 5.5e-11 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedg 40 Dv+EC+ g hnC +e + C+N+ Gs eC+C+eg+e dg FUN_001024-T1 238 DVNECKLGIHNC-SEYADCTNSFGSHECTCHEGFE--GDG 274 9***********.8********************9..555 PP == domain 6 score: 40.1 bits; conditional E-value: 1.7e-13 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedg 40 Dv+EC+ g hnC +e++ C+N++Gs++C+C++g+e dg FUN_001024-T1 279 DVNECERGIHNC-SEHADCTNSIGSYRCTCHQGFE--GDG 315 9***********.8********************9..555 PP == domain 7 score: 36.3 bits; conditional E-value: 2.6e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC+ hnC + ++ C+N++Gs+ C+C++g+e dg +C FUN_001024-T1 320 DVNECKRRIHNC-SVHADCTNSIGSYGCTCHQGFE--GDGWAC 359 9***********.8********************9..666555 PP == domain 8 score: 34.6 bits; conditional E-value: 9.4e-12 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegye 35 D+dEC+ +nC ++++ C+N++G f+C+C++g+e FUN_001024-T1 361 DIDECKVKVDNC-SRHAFCTNNVGAFSCECKKGFE 394 9***********.8********************9 PP == domain 9 score: 41.2 bits; conditional E-value: 7.8e-14 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 Dv+EC gthnC d +++C+N +Gs+ C+C++gy+ dg +C FUN_001024-T1 402 DVNECWRGTHNC-DTHASCQNIDGSYVCSCSSGYK--GDGRTC 441 9***********.7*********************..888888 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 1.6 7.2e-07 0.0019 2 24 .] 99 119 .. 98 119 .. 0.95 2 ! 27.7 0.3 9.8e-10 2.5e-06 1 24 [] 138 159 .. 138 159 .. 0.98 3 ! 27.5 4.6 1.1e-09 2.8e-06 2 24 .] 180 200 .. 179 200 .. 0.97 4 ! 31.4 1.5 6.8e-11 1.7e-07 2 24 .] 221 241 .. 220 241 .. 0.97 5 ! 26.1 1.7 3e-09 7.7e-06 1 24 [] 261 282 .. 261 282 .. 0.96 6 ! 31.8 2.2 5.2e-11 1.3e-07 1 24 [] 302 323 .. 302 323 .. 0.99 7 ! 26.0 3.1 3.2e-09 8.3e-06 1 24 [] 343 364 .. 343 364 .. 0.96 8 ! 24.1 0.3 1.3e-08 3.4e-05 2 24 .] 385 405 .. 384 405 .. 0.97 9 ! 22.1 5.4 5.5e-08 0.00014 1 19 [. 425 441 .. 425 442 .. 0.97 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 7.2e-07 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 tC+C+ GY g+G C D +E FUN_001024-T1 99 HTCQCNVGYH--GNGSVCYDLNE 119 59********..9*********9 PP == domain 2 score: 27.7 bits; conditional E-value: 9.8e-10 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 S+ C C +G++ g+G tC D+DE FUN_001024-T1 138 SFNCDCLQGFQ--GNGMTCLDVDE 159 899********..9*********9 PP == domain 3 score: 27.5 bits; conditional E-value: 1.1e-09 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 Y C+C +G++ gDG+tC D+DE FUN_001024-T1 180 YNCTCFSGFE--GDGKTCGDVDE 200 99********..**********9 PP == domain 4 score: 31.4 bits; conditional E-value: 6.8e-11 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 Y CsC +GY+ gDG +C+D++E FUN_001024-T1 221 YNCSCLNGYQ--GDGWNCTDVNE 241 99********..**********9 PP == domain 5 score: 26.1 bits; conditional E-value: 3e-09 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 S C+C++G++ gDG C D++E FUN_001024-T1 261 SHECTCHEGFE--GDGWVCNDVNE 282 789********..**********9 PP == domain 6 score: 31.8 bits; conditional E-value: 5.2e-11 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY+C+C++G++ gDG C D++E FUN_001024-T1 302 SYRCTCHQGFE--GDGWVCNDVNE 323 9**********..**********9 PP == domain 7 score: 26.0 bits; conditional E-value: 3.2e-09 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 SY C+C++G++ gDG C DIDE FUN_001024-T1 343 SYGCTCHQGFE--GDGWACSDIDE 364 788********..**********9 PP == domain 8 score: 24.1 bits; conditional E-value: 1.3e-08 cEGF 2 YtCsCppGYtLagDGrtCvDIDE 24 + C+C++G++ g+G C D++E FUN_001024-T1 385 FSCECKKGFE--GNGWLCDDVNE 405 89********..9*********9 PP == domain 9 score: 22.1 bits; conditional E-value: 5.5e-08 cEGF 1 SYtCsCppGYtLagDGrtC 19 SY+CsC +GY+ gDGrtC FUN_001024-T1 425 SYVCSCSSGYK--GDGRTC 441 9**********..****** PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 6.6 8.5e-05 0.22 5 31 .. 82 110 .. 79 111 .. 0.85 2 ! 12.7 10.8 6.4e-05 0.16 3 31 .. 123 150 .. 114 151 .. 0.92 3 ! 17.9 8.0 1.6e-06 0.004 1 31 [. 160 191 .. 160 192 .. 0.92 4 ! 22.7 7.2 5e-08 0.00013 4 31 .. 206 232 .. 201 233 .. 0.92 5 ! 12.5 8.6 7.4e-05 0.19 4 31 .. 247 273 .. 240 274 .. 0.90 6 ! 14.5 10.6 1.8e-05 0.047 4 31 .. 288 314 .. 277 315 .. 0.91 7 ! 9.5 10.1 0.00066 1.7 4 31 .. 329 355 .. 318 356 .. 0.90 8 ! 19.5 5.2 4.9e-07 0.0013 4 31 .. 370 396 .. 365 397 .. 0.91 9 ! 19.8 5.6 3.9e-07 0.001 4 31 .. 411 437 .. 408 438 .. 0.94 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 8.5e-05 EGF 5 p..CsngGtCvdtprggytCiCpeGytGk 31 + C+ ++ C +++tC+C +Gy+G+ FUN_001024-T1 82 KtlCDVNAVCKAIDHSHHTCQCNVGYHGN 110 44699*****888888************7 PP == domain 2 score: 12.7 bits; conditional E-value: 6.4e-05 EGF 3 pnpCsngGtCvdtprggytCiCpeGytGk 31 +++C +++C +t g+++C+C +G+ G+ FUN_001024-T1 123 SHNCGDNARCKNTM-GSFNCDCLQGFQGN 150 489***********.************97 PP == domain 3 score: 17.9 bits; conditional E-value: 1.6e-06 EGF 1 Csp..npCsngGtCvdtprggytCiCpeGytGk 31 Cs+ ++Cs ++ C +t g y+C+C G+ G+ FUN_001024-T1 160 CSDsvDNCSQHAYCNNTL-GAYNCTCFSGFEGD 191 7776789***********.************97 PP == domain 4 score: 22.7 bits; conditional E-value: 5e-08 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++C+ +++C++++ g y+C C +Gy G+ FUN_001024-T1 206 HQCHKHAFCINNE-GAYNCSCLNGYQGD 232 67***********.************97 PP == domain 5 score: 12.5 bits; conditional E-value: 7.4e-05 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs + C ++ g++ C+C eG+ G+ FUN_001024-T1 247 HNCSEYADCTNSF-GSHECTCHEGFEGD 273 89*******9999.************97 PP == domain 6 score: 14.5 bits; conditional E-value: 1.8e-05 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs ++ C ++ g+y C+C +G+ G+ FUN_001024-T1 288 HNCSEHADCTNSI-GSYRCTCHQGFEGD 314 89***********.************97 PP == domain 7 score: 9.5 bits; conditional E-value: 0.00066 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs ++ C ++ g+y C+C +G+ G+ FUN_001024-T1 329 HNCSVHADCTNSI-GSYGCTCHQGFEGD 355 89***********.************97 PP == domain 8 score: 19.5 bits; conditional E-value: 4.9e-07 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++Cs +++C ++ g ++C+C+ G+ G+ FUN_001024-T1 370 DNCSRHAFCTNNV-GAFSCECKKGFEGN 396 78***********.************97 PP == domain 9 score: 19.8 bits; conditional E-value: 3.9e-07 EGF 4 npCsngGtCvdtprggytCiCpeGytGk 31 ++C+ ++ C + g+y C C+ Gy+G+ FUN_001024-T1 411 HNCDTHASCQNID-GSYVCSCSSGYKGD 437 78***********.*************7 PP >> EGF_MSP1_1 MSP1 EGF domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 6.5 0.00027 0.69 2 36 .. 79 114 .. 78 115 .. 0.90 2 ! 17.3 7.1 2e-06 0.005 1 37 [] 119 155 .. 119 155 .. 0.95 3 ! 14.7 8.0 1.3e-05 0.033 2 36 .. 160 195 .. 159 196 .. 0.91 4 ! 18.9 8.6 6e-07 0.0015 5 36 .. 206 236 .. 200 237 .. 0.92 5 ! 13.4 7.2 3.2e-05 0.082 5 36 .. 247 277 .. 241 278 .. 0.89 6 ! 15.3 7.4 8.3e-06 0.021 2 36 .. 283 318 .. 282 319 .. 0.86 7 ! 13.7 6.2 2.6e-05 0.066 5 36 .. 329 359 .. 323 360 .. 0.88 8 ! 6.9 8.0 0.0035 9 5 35 .. 370 399 .. 364 401 .. 0.86 9 ! 23.0 6.2 3.2e-08 8.2e-05 5 37 .] 411 442 .. 405 442 .. 0.87 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00027 EGF_MSP1_1 2 Cvk.vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C+ + c+ NA C + C C+ gy +g+ C FUN_001024-T1 79 CRHkTLCDVNAVCKAIDHSHHTCQCNVGYHGNGSVC 114 766588*******9999899*************999 PP == domain 2 score: 17.3 bits; conditional E-value: 2e-06 EGF_MSP1_1 1 eCvk.vkcPaNAkCvrhadgreECrCllgykkeggkCv 37 eC++ +c +NA C + + g+ C Cl g+ +g +C+ FUN_001024-T1 119 ECLGsHNCGDNARCKNTM-GSFNCDCLQGFQGNGMTCL 155 698889************.******************6 PP == domain 3 score: 14.7 bits; conditional E-value: 1.3e-05 EGF_MSP1_1 2 Cvk..vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C + +c ++A C + + g + C C g+ +g +C FUN_001024-T1 160 CSDsvDNCSQHAYCNNTL-GAYNCTCFSGFEGDGKTC 195 7766579***********.****************** PP == domain 4 score: 18.9 bits; conditional E-value: 6e-07 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c ++A+C+++ g + C Cl gy +g C FUN_001024-T1 206 HQCHKHAFCINNE-GAYNCSCLNGYQGDGWNC 236 58***********.**************9988 PP == domain 5 score: 13.4 bits; conditional E-value: 3.2e-05 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c + A+C +++ g+ EC C g+ +g C FUN_001024-T1 247 HNCSEYADCTNSF-GSHECTCHEGFEGDGWVC 277 5899*********.***********9998666 PP == domain 6 score: 15.3 bits; conditional E-value: 8.3e-06 EGF_MSP1_1 2 Cvk..vkcPaNAkCvrhadgreECrCllgykkeggkC 36 C+ +c ++A+C ++ g++ C C g+ +g C FUN_001024-T1 283 CERgiHNCSEHADCTNSI-GSYRCTCHQGFEGDGWVC 318 5554579***********.***********9998666 PP == domain 7 score: 13.7 bits; conditional E-value: 2.6e-05 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkC 36 +c +A+C ++ g++ C C g+ +g C FUN_001024-T1 329 HNCSVHADCTNSI-GSYGCTCHQGFEGDGWAC 359 6899*********.***********9999877 PP == domain 8 score: 6.9 bits; conditional E-value: 0.0035 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggk 35 +c +A+C ++ g C C+ g+ +g FUN_001024-T1 370 DNCSRHAFCTNNV-GAFSCECKKGFEGNGWL 399 58***********.***********988855 PP == domain 9 score: 23.0 bits; conditional E-value: 3.2e-08 EGF_MSP1_1 5 vkcPaNAkCvrhadgreECrCllgykkeggkCv 37 +c+ +A C + + g++ C C gyk +g +C+ FUN_001024-T1 411 HNCDTHASCQNID-GSYVCSCSSGYKGDGRTCM 442 79*******6665.******************5 PP >> FXa_inhibition Coagulation Factor Xa inhibitory site # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 7.6 0.16 4e+02 8 28 .. 85 108 .. 79 114 .. 0.79 2 ! 7.4 9.8 0.0027 6.8 7 36 .] 125 154 .. 120 154 .. 0.81 3 ! 11.0 12.3 0.0002 0.52 1 36 [] 160 195 .. 160 195 .. 0.93 4 ! 11.8 9.0 0.00011 0.29 1 35 [. 201 235 .. 201 236 .. 0.81 5 ! 8.3 8.3 0.0014 3.7 6 28 .. 247 271 .. 242 283 .. 0.81 6 ! 10.2 9.4 0.00037 0.94 6 28 .. 288 312 .. 277 320 .. 0.80 7 ! 8.0 9.1 0.0017 4.4 1 28 [. 324 353 .. 324 359 .. 0.82 8 ! 14.3 4.4 1.9e-05 0.049 1 28 [. 365 394 .. 365 406 .. 0.89 9 ! 10.5 13.0 0.00028 0.72 7 36 .] 412 441 .. 400 441 .. 0.85 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.16 FXa_inhibition 8 Cs..hlClntpgg.ytCsCpeGye 28 C+ C++ ++ +tC+C Gy+ FUN_001024-T1 85 CDvnAVCKAIDHShHTCQCNVGYH 108 555578999966449********7 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0027 FXa_inhibition 7 gCs..hlClntpggytCsCpeGyeLsdDgktC 36 C+ C+nt g++ C C +G++ +g tC FUN_001024-T1 125 NCGdnARCKNTMGSFNCDCLQGFQ--GNGMTC 154 4554478***************99..667777 PP == domain 3 score: 11.0 bits; conditional E-value: 0.0002 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgktC 36 Cs+ Cs +C nt g y C+C +G+e DgktC FUN_001024-T1 160 CSDSVDNCSqhAYCNNTLGAYNCTCFSGFE--GDGKTC 195 9999999**6559****************9..99**** PP == domain 4 score: 11.8 bits; conditional E-value: 0.00011 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGyeLsdDgkt 35 C+v ++C +C+n+ g y CsC +Gy+ Dg + FUN_001024-T1 201 CKVMLHQCHkhAFCINNEGAYNCSCLNGYQ--GDGWN 235 666667898767*****************9..55555 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0014 FXa_inhibition 6 ggCshl..ClntpggytCsCpeGye 28 + Cs + C+n+ g+++C+C+eG+e FUN_001024-T1 247 HNCSEYadCTNSFGSHECTCHEGFE 271 67996666***************98 PP == domain 6 score: 10.2 bits; conditional E-value: 0.00037 FXa_inhibition 6 ggCs..hlClntpggytCsCpeGye 28 + Cs C+n+ g+y+C+C++G+e FUN_001024-T1 288 HNCSehADCTNSIGSYRCTCHQGFE 312 56886334***************98 PP == domain 7 score: 8.0 bits; conditional E-value: 0.0017 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+ + + Cs C+n+ g+y C+C++G+e FUN_001024-T1 324 CKRRIHNCSvhADCTNSIGSYGCTCHQGFE 353 6677788998446***************98 PP == domain 8 score: 14.3 bits; conditional E-value: 1.9e-05 FXa_inhibition 1 CsvnNggCs..hlClntpggytCsCpeGye 28 C+v+ Cs +C+n+ g ++C C +G+e FUN_001024-T1 365 CKVKVDNCSrhAFCTNNVGAFSCECKKGFE 394 9999999**978****************98 PP == domain 9 score: 10.5 bits; conditional E-value: 0.00028 FXa_inhibition 7 gCs..hlClntpggytCsCpeGyeLsdDgktC 36 C+ C n g+y+CsC +Gy+ Dg+tC FUN_001024-T1 412 NCDthASCQNIDGSYVCSCSSGYK--GDGRTC 441 47653569999*************..99**** PP >> ADGRF3_N ADGRF3-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 9.9 4.1e-05 0.1 3 44 .. 90 132 .. 88 136 .. 0.87 2 ! 14.5 5.8 1.9e-05 0.049 3 42 .. 131 167 .. 129 173 .. 0.86 3 ! 8.5 6.2 0.0014 3.7 4 45 .. 173 215 .. 170 218 .. 0.79 4 ? 4.8 10.6 0.021 52 5 37 .. 215 246 .. 211 258 .. 0.75 5 ? 5.7 10.0 0.011 29 4 44 .. 255 296 .. 252 300 .. 0.78 6 ? 3.8 13.1 0.044 1.1e+02 3 43 .. 295 332 .. 289 341 .. 0.82 7 ? 5.7 7.7 0.011 29 3 42 .. 336 372 .. 334 378 .. 0.84 8 ! 7.5 9.3 0.003 7.7 4 43 .. 378 414 .. 375 422 .. 0.77 9 ! 9.5 5.2 0.00074 1.9 4 38 .. 419 453 .. 415 461 .. 0.82 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 4.1e-05 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqess.eeqsCsC 44 +C++ +++ +C+C+ gY+ n svC+ ++C +s+ +++ +C FUN_001024-T1 90 VCKAIDHSHHTCQCNVGYHGNGSVCYDLNECLGSHnCGDNARC 132 8**9999*************************99944666666 PP == domain 2 score: 14.5 bits; conditional E-value: 1.9e-05 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 C+++ g+++C C++g+q n +C ++C++s ++C FUN_001024-T1 131 RCKNTM-GSFNCDCLQGFQGNGMTCLDVDECSDSV--DNC 167 588885.88***********************997..555 PP == domain 3 score: 8.5 bits; conditional E-value: 0.0014 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqess.e.eqsCsCl 45 Cn++ g ++C+C sg++ + ++C ++C+ + +++ C+ FUN_001024-T1 173 CNNTL-GAYNCTCFSGFEGDGKTCGDVDECKVMLhQcHKHAFCI 215 99885.78**********************97652235555666 PP == domain 4 score: 4.8 bits; conditional E-value: 0.021 ADGRF3_N 5 nvsgngesqCaCesgYqWnasvCskyppCqess 37 +++g ++C+C++gYq + C+ ++C+ FUN_001024-T1 215 I-NNEGAYNCSCLNGYQGDGWNCTDVNECKLGI 246 4.45799**********9999999999998444 PP == domain 5 score: 5.7 bits; conditional E-value: 0.011 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqess.e.eqsCsC 44 C++s g+ +C+C++g++ + vC+ ++C++ + +++ +C FUN_001024-T1 255 CTNS-FGSHECTCHEGFEGDGWVCNDVNECERGIhNcSEHADC 296 7776.4779*********************9766333555566 PP == domain 6 score: 3.8 bits; conditional E-value: 0.044 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsCs 43 +C++s g+++C+C++g++ + vC+ ++C+++ ++Cs FUN_001024-T1 295 DCTNS-IGSYRCTCHQGFEGDGWVCNDVNECKRRI--HNCS 332 58776.588***********************988..4443 PP == domain 7 score: 5.7 bits; conditional E-value: 0.011 ADGRF3_N 3 eCnvsgngesqCaCesgYqWnasvCskyppCqesseeqsC 42 +C++s g++ C+C++g++ + +Cs ++C+ + ++C FUN_001024-T1 336 DCTNS-IGSYGCTCHQGFEGDGWACSDIDECKVKV--DNC 372 58776.5889*********************9887..555 PP == domain 8 score: 7.5 bits; conditional E-value: 0.003 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCskyppCqesseeqsCs 43 C+++ g ++C+C++g++ n +C ++C + + ++C+ FUN_001024-T1 378 CTNN-VGAFSCECKKGFEGNGWLCDDVNECWRGT--HNCD 414 7776.588**********************9766..3332 PP == domain 9 score: 9.5 bits; conditional E-value: 0.00074 ADGRF3_N 4 CnvsgngesqCaCesgYqWnasvCs.kyppCqesse 38 C++ +g++ C+C sgY+ + ++C +y+ C+++++ FUN_001024-T1 419 CQN-IDGSYVCSCSSGYKGDGRTCMgRYERCRHRNT 453 665.4799****************757999*98874 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.4 0.00038 0.97 10 22 .] 95 107 .. 87 107 .. 0.75 2 ? -3.2 0.7 7.6 1.9e+04 3 10 .. 110 117 .. 109 120 .. 0.74 3 ! 10.4 4.7 0.00041 1 1 22 [] 126 147 .. 126 147 .. 0.97 4 ? -3.3 0.3 8.1 2.1e+04 5 9 .. 151 156 .. 149 161 .. 0.58 5 ! 9.1 6.6 0.0011 2.7 1 21 [. 167 187 .. 167 188 .. 0.91 6 ! 13.0 6.2 6.2e-05 0.16 1 22 [] 208 229 .. 208 229 .. 0.98 7 ? -2.6 0.3 5 1.3e+04 4 16 .. 233 242 .. 232 243 .. 0.65 8 ! 9.7 4.0 0.00064 1.6 1 22 [] 249 270 .. 249 270 .. 0.91 9 ? -1.8 0.2 2.9 7.4e+03 4 16 .. 274 283 .. 273 284 .. 0.69 10 ! 19.0 4.2 7.8e-07 0.002 1 22 [] 290 311 .. 290 311 .. 0.98 11 ? -2.0 0.2 3.3 8.5e+03 4 16 .. 315 324 .. 314 325 .. 0.66 12 ! 8.3 5.6 0.0018 4.6 4 22 .] 334 352 .. 331 352 .. 0.91 13 ! 17.8 2.6 1.9e-06 0.0048 1 22 [] 372 393 .. 372 393 .. 0.98 14 ? 0.8 0.5 0.41 1.1e+03 3 14 .. 396 404 .. 395 406 .. 0.73 15 ! 14.7 5.1 1.8e-05 0.046 1 22 [] 413 434 .. 413 434 .. 0.96 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00038 hEGF 10 gvngykCqCppGy 22 +++++CqC+ Gy FUN_001024-T1 95 DHSHHTCQCNVGY 107 34556*******9 PP == domain 2 score: -3.2 bits; conditional E-value: 7.6 hEGF 3 NGGtCvdg 10 NG C d+ FUN_001024-T1 110 NGSVCYDL 117 88899876 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00041 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C +++C ++ +++ C C +G+ FUN_001024-T1 126 CGDNARCKNTMGSFNCDCLQGF 147 9999*****************9 PP == domain 4 score: -3.3 bits; conditional E-value: 8.1 hEGF 5 G.tCvd 9 G tC d FUN_001024-T1 151 GmTCLD 156 448984 PP == domain 5 score: 9.1 bits; conditional E-value: 0.0011 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C++++ C+++ + y C C +G FUN_001024-T1 167 CSQHAYCNNTLGAYNCTCFSG 187 ******************555 PP == domain 6 score: 13.0 bits; conditional E-value: 6.2e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++ C+++ + y C+C Gy FUN_001024-T1 208 CHKHAFCINNEGAYNCSCLNGY 229 999******************9 PP == domain 7 score: -2.6 bits; conditional E-value: 5 hEGF 4 GGtCvdgvngykC 16 G+ C+ + ++C FUN_001024-T1 233 GWNCT---DVNEC 242 78899...44555 PP == domain 8 score: 9.7 bits; conditional E-value: 0.00064 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ + C++ ++++C C +G+ FUN_001024-T1 249 CSEYADCTNSFGSHECTCHEGF 270 666789***************9 PP == domain 9 score: -1.8 bits; conditional E-value: 2.9 hEGF 4 GGtCvdgvngykC 16 G+ C+ + ++C FUN_001024-T1 274 GWVCN---DVNEC 283 88999...55556 PP == domain 10 score: 19.0 bits; conditional E-value: 7.8e-07 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++ C++ +++y+C C +G+ FUN_001024-T1 290 CSEHADCTNSIGSYRCTCHQGF 311 999******************9 PP == domain 11 score: -2.0 bits; conditional E-value: 3.3 hEGF 4 GGtCvdgvngykC 16 G+ C+ + ++C FUN_001024-T1 315 GWVCN---DVNEC 324 88999...44455 PP == domain 12 score: 8.3 bits; conditional E-value: 0.0018 hEGF 4 GGtCvdgvngykCqCppGy 22 ++ C++ +++y C C +G+ FUN_001024-T1 334 HADCTNSIGSYGCTCHQGF 352 789***************9 PP == domain 13 score: 17.8 bits; conditional E-value: 1.9e-06 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C+ ++ C+++v+ ++C+C+ G+ FUN_001024-T1 372 CSRHAFCTNNVGAFSCECKKGF 393 9*******************98 PP == domain 14 score: 0.8 bits; conditional E-value: 0.41 hEGF 3 NGGtCvdgvngy 14 NG+ C+d + FUN_001024-T1 396 NGWLCDDV---N 404 9*****54...4 PP == domain 15 score: 14.7 bits; conditional E-value: 1.8e-05 hEGF 1 ClNGGtCvdgvngykCqCppGy 22 C +++C++ ++y+C+C +Gy FUN_001024-T1 413 CDTHASCQNIDGSYVCSCSSGY 434 8889*****************9 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 6.9 7.7e-05 0.2 6 40 .. 84 114 .. 78 115 .. 0.87 2 ! 14.7 6.6 1.3e-05 0.033 5 40 .. 124 154 .. 119 155 .. 0.91 3 ? 4.1 8.3 0.028 72 6 40 .. 166 195 .. 159 196 .. 0.88 4 ? 4.3 12.0 0.024 61 6 33 .. 207 230 .. 191 237 .. 0.84 5 ! 5.6 10.1 0.0095 24 1 33 [. 241 271 .. 234 284 .. 0.88 6 ? 4.1 10.3 0.028 71 6 33 .. 289 312 .. 276 325 .. 0.82 7 ? 3.9 7.6 0.031 78 2 32 .. 324 352 .. 317 360 .. 0.85 8 ? 4.5 8.0 0.021 53 2 32 .. 365 393 .. 364 406 .. 0.83 9 ! 9.1 8.2 0.00075 1.9 6 40 .. 412 441 .. 400 442 .. 0.90 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 7.7e-05 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 C +n++Ck h++C+Cn Gy n+++C FUN_001024-T1 84 LCDVNAVCKAI---DHSHHTCQCNVGYH-GNGSVC 114 4*********9...899**********9.999999 PP == domain 2 score: 14.7 bits; conditional E-value: 1.3e-05 Plasmod_Pvs28 5 KaCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +Cg+n+ Ck++ +++ C+C G+ n+++C FUN_001024-T1 124 HNCGDNARCKNT----MGSFNCDCLQGFQ-GNGMTC 154 58**********....*************.****** PP == domain 3 score: 4.1 bits; conditional E-value: 0.028 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +C ++++C ++ ++y C C G+ ++++C FUN_001024-T1 166 NCSQHAYCNNT----LGAYNCTCFSGFE-GDGKTC 195 7**********....*************.999999 PP == domain 4 score: 4.3 bits; conditional E-value: 0.024 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyv 33 C ++ C+++ +++y CsC +Gy FUN_001024-T1 207 QCHKHAFCINN----EGAYNCSCLNGYQ 230 5888999****....***********95 PP == domain 5 score: 5.6 bits; conditional E-value: 0.0095 Plasmod_Pvs28 1 kCql..KaCgengkCklglpqnsnhykCsCniGyv 33 +C+l +C e++ C++ ++++C C +G+ FUN_001024-T1 241 ECKLgiHNCSEYADCTNS----FGSHECTCHEGFE 271 68889989**********....*********9996 PP == domain 6 score: 4.1 bits; conditional E-value: 0.028 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyv 33 +C e++ C++ ++y+C C G+ FUN_001024-T1 289 NCSEHADCTNS----IGSYRCTCHQGFE 312 7**********....*********8885 PP == domain 7 score: 3.9 bits; conditional E-value: 0.031 Plasmod_Pvs28 2 Cql..KaCgengkCklglpqnsnhykCsCniGy 32 C+ +C +++ C++ ++y C C G+ FUN_001024-T1 324 CKRriHNCSVHADCTNS----IGSYGCTCHQGF 352 5556668**********....********9998 PP == domain 8 score: 4.5 bits; conditional E-value: 0.021 Plasmod_Pvs28 2 CqlK..aCgengkCklglpqnsnhykCsCniGy 32 C+ K +C ++ C+++ ++++ C C++G+ FUN_001024-T1 365 CKVKvdNCSRHAFCTNN----VGAFSCECKKGF 393 6664226999*******....***********9 PP == domain 9 score: 9.1 bits; conditional E-value: 0.00075 Plasmod_Pvs28 6 aCgengkCklglpqnsnhykCsCniGyvllnenkC 40 +C ++ C + +++y+CsC Gy+ ++ +C FUN_001024-T1 412 NCDTHASCQNI----DGSYVCSCSSGYK-GDGRTC 441 69999******....*************.999998 PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -13.2 130.1 10 2.6e+04 1 231 [. 165 451 .. 67 463 .. 0.78 Alignments for each domain: == domain 1 score: -13.2 bits; conditional E-value: 10 EGF_TEN 1 knCsgrGeCveg....kCeCkkgfeG..eDCsk.avcpv...lCsgrGayekg....kCeCeegykGe..eC.evkvkeceaancsgrGecie... 76 +nCs++ C+++ +C+C++gfeG + C+ ++c+v +C+++ + + +C C +gy+G +C +v+ ++ ncs+ +c++ FUN_001024-T1 165 DNCSQHAYCNNTlgayNCTCFSGFEGdgKTCGDvDECKVmlhQCHKHAFCINNegayNCSCLNGYQGDgwNCtDVNECKLGIHNCSEYADCTNsfg 260 5899*****98433448*******86225787535665422279999999864223469******9863367345666677899999999997665 PP EGF_TEN 77 .gkCvCkpgykGk..kCee.ktcld..anCsgngvCvng....kCvCeegytged..Celekkack...ekcskkgklvkesgs..cvcdegytge 155 ++C+C++g++G+ C+ ++c++ +nCs++ C+n+ +C+C++g++g+ C+ + +ck ++cs ++ ++++ gs c+c++g++g+ FUN_001024-T1 261 sHECTCHEGFEGDgwVCNDvNECERgiHNCSEHADCTNSigsyRCTCHQGFEGDGwvCNDVN-ECKrriHNCSVHADCTNSIGSygCTCHQGFEGD 355 579*******9863368752678754479*******99544558*******98744488754.343233788899999887665559***999987 PP EGF_TEN 156 ..dc.eeetcsl...dCgehgkCvesk....CkCdegwtGe..kCe.kktC...esrCkehGvckn..G..tCiCekGfngeecsleaCpnnCnnh 231 c + +c++ +C++h+ C+++ C+C++g++G+ C+ ++C +++C +h c+n G C C++G++g+ + + + C+++ FUN_001024-T1 356 gwACsDIDECKVkvdNCSRHAFCTNNVgafsCECKKGFEGNgwLCDdVNECwrgTHNCDTHASCQNidGsyVCSCSSGYKGDGRTCMGRYERCRHR 451 33463456787633469******99744455*******987335883457844457999*****9876533699*****99887776666666554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (476 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1175 (0.0459973); expected 510.9 (0.02) Passed bias filter: 531 (0.0207868); expected 510.9 (0.02) Passed Vit filter: 78 (0.00305344); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 4441.94 // Query: FUN_001025-T1 [L=383] Description: FUN_001025 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-14 53.5 17.8 2.2e-10 41.0 6.9 2.2 2 ApoL Apolipoprotein L ------ inclusion threshold ------ 0.059 14.2 0.7 0.25 12.1 0.3 2.3 3 DUF334 Domain of unknown function (DUF334) 0.073 13.8 0.0 0.18 12.6 0.0 1.6 1 Uds1 Up-regulated During Septation 0.14 12.9 0.5 0.39 11.5 0.5 1.7 1 BibA_N BibA adhesin stalk domain 0.39 11.3 1.8 0.55 10.8 0.3 2.0 2 PspB Phage shock protein B Domain annotation for each model (and alignments): >> ApoL Apolipoprotein L # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.0 6.9 4.3e-14 2.2e-10 63 209 .. 61 219 .. 36 266 .. 0.71 2 ! 17.0 4.5 8.7e-07 0.0044 188 294 .. 275 382 .. 250 383 .] 0.86 Alignments for each domain: == domain 1 score: 41.0 bits; conditional E-value: 4.3e-14 ApoL 63 eLeesIkkLralAdevdkvHrdctisnvvasstgavSgiLtilGlaLaPvtaGlSlvLsatGlGLGaaaavtgvstsiveeskkssakaeAsrlvs 158 ++ ++k+Lr Ad +dkv +dc +++ v s + ++ g+L+i+G ++ G+++ L+ +G LG++ + ++ t ve+s +ss +eA ++v+ FUN_001025-T1 61 RVDRTVKHLRDAADFLDKVWKDCKVASAVGSGANIAGGVLSIAGGIATIMSGGAAFPLLLAGGSLGVTGTCINLGTTAVESSINSSIVQEADEVVQ 156 566789**************************************999999999999**************************************99 PP ApoL 159 tsldklkvvaevl.....eentpkvlslakkli.......qvlkeiekniralrlakanprlv 209 ++ + + v+ + ++n+++++ la i v+k ++ +r laka p ++ FUN_001025-T1 157 NAHHAIENVKRRIialktGKNQVHLVLLAGLAIkilgkdhLVVKLLKDLVRSDVLAKALPSVM 219 999888888764311111233333333333333333333323333333344444444444444 PP == domain 2 score: 17.0 bits; conditional E-value: 8.7e-07 ApoL 188 vlkeiekniralrlakanprlvakakrlittgrisaqsakqvqka.fegtalamskgarilgaatagvflllDvvslvkeskhLheGakaesAeeL 282 ++k+++ ++ a + + r+ aka + i t +s ++++ v k+ +++ a +k+a + + ++++fl+lD + l + ++ e + A L FUN_001025-T1 275 TTKKVGAQLTAKGTKRIVKRVGAKAGKKIGTTAVSKEAGNTVTKSgTKAASKAAAKQAGAVIIGVSAAFLVLDAIDLAFTVRDIVENQGSDAARIL 370 4677777778888888888899*******************988725677788888888888889999**************************** PP ApoL 283 rkqAqeLeekLe 294 r +A e e L+ FUN_001025-T1 371 RCKADEYEALLD 382 ******999886 PP >> DUF334 Domain of unknown function (DUF334) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 1.5 7.6e+03 63 63 .. 73 73 .. 38 114 .. 0.58 2 ? 12.1 0.3 4.9e-05 0.25 16 88 .. 147 225 .. 136 233 .. 0.85 3 ? -2.9 0.0 2.2 1.1e+04 28 61 .. 322 355 .. 314 361 .. 0.72 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1.5 DUF334 63 r 63 FUN_001025-T1 73 A 73 2 PP == domain 2 score: 12.1 bits; conditional E-value: 4.9e-05 DUF334 16 vreeikrmlrevkasheayqkkikllyrgigamllvfmlfalvmtigrdfm......dflhvdvlqkaiasklkasegf 88 + +e +++++ +++ e+ +++i l +g + lv++ + +g+d + d++ dvl ka+ s +ka +g FUN_001025-T1 147 IVQEADEVVQNAHHAIENVKRRIIALKTGKNQVHLVLLAGLAIKILGKDHLvvkllkDLVRSDVLAKALPSVMKALQGV 225 4578888999999999********************9998889999**9754444448999**************9986 PP == domain 3 score: -2.9 bits; conditional E-value: 2.2 DUF334 28 kasheayqkkikllyrgigamllvfmlfalvmti 61 ka+ +a k+ + g+ a +lv+ + l +t+ FUN_001025-T1 322 KAASKAAAKQAGAVIIGVSAAFLVLDAIDLAFTV 355 5556666777777888888888888777776665 PP >> Uds1 Up-regulated During Septation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 3.4e-05 0.18 14 113 .. 32 184 .. 27 188 .. 0.88 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 3.4e-05 Uds1 14 efeiLsleeveelkkelaaLssrlealrkklale.tklrdaaqsLsrlyssskks......................................... 67 +++ L++e++++l e++ +++ + ++ ++ + lrdaa L ++ ++ k FUN_001025-T1 32 RWDALNQEDMQQLVNEIQDVTDNVLEMNVRVDRTvKHLRDAADFLDKVW-KDCKVasavgsganiaggvlsiaggiatimsggaafplllaggslg 126 7899*********************9999997651569**********9.44444599************************************** PP Uds1 68 ...........s.rssksseslkkaeeelaeserkveelaseleklekrlaevqrrLL 113 + +ss +s +++a+e ++++ + +e++++ + l++ +++v+ LL FUN_001025-T1 127 vtgtcinlgttAvESSINSSIVQEADEVVQNAHHAIENVKRRIIALKTGKNQVHLVLL 184 ********99743555555789*****************************9998888 PP >> BibA_N BibA adhesin stalk domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.5 7.6e-05 0.39 28 47 .. 136 156 .. 133 157 .. 0.90 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 7.6e-05 BibA_N 28 vksiksalds.fvaeAkkvan 47 +++ s+++s +v+eA +v++ FUN_001025-T1 136 TTAVESSINSsIVQEADEVVQ 156 5899*****99*********9 PP >> PspB Phage shock protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.3 0.00011 0.55 8 55 .. 6 53 .. 1 70 [. 0.83 2 ? -1.4 0.1 0.71 3.6e+03 31 60 .. 143 172 .. 140 174 .. 0.81 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00011 PspB 8 pliifvlfVapiWLiLHYrskrkkskglsaeeeqrLeellekAerlee 55 ++ fv++++++W + + kr++ +++a +++ +++l+++ + + FUN_001025-T1 6 VILGFVVIIMLLWFVVREIRKRREIGRWDALNQEDMQQLVNEIQDVTD 53 56669******************9999999999999999888766555 PP == domain 2 score: -1.4 bits; conditional E-value: 0.71 PspB 31 kskglsaeeeqrLeellekAerleeRietl 60 ++++ +e + +++ ++ e+ ++Ri +l FUN_001025-T1 143 INSSIVQEADEVVQNAHHAIENVKRRIIAL 172 567788888889999999999999999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (383 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1854 (0.0725778); expected 510.9 (0.02) Passed bias filter: 1057 (0.041378); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.36u 0.42s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 3679.38 // Query: FUN_001026-T1 [L=659] Description: FUN_001026 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (659 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 945 (0.0369935); expected 510.9 (0.02) Passed bias filter: 516 (0.0201996); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6291.39 // Query: FUN_001026-T2 [L=564] Description: FUN_001026 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (564 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 774 (0.0302995); expected 510.9 (0.02) Passed bias filter: 375 (0.01468); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 5397.38 // Query: FUN_001027-T1 [L=299] Description: FUN_001027 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (299 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 940 (0.0367978); expected 510.9 (0.02) Passed bias filter: 378 (0.0147974); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 3034.85 // Query: FUN_001028-T1 [L=422] Description: FUN_001028 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (422 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1252 (0.0490115); expected 510.9 (0.02) Passed bias filter: 577 (0.0225876); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4098.21 // Query: FUN_001029-T1 [L=91] Description: FUN_001029 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (91 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 589 (0.0230573); expected 510.9 (0.02) Passed bias filter: 440 (0.0172245); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 908.87 // Query: FUN_001030-T1 [L=71] Description: FUN_001030 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.1 13.5 0.0 0.12 13.3 0.0 1.1 1 DUF3899 Domain of unknown function (DUF3899) 0.13 12.9 0.0 0.17 12.6 0.0 1.3 1 DUF3653 Phage protein 7.7 7.5 5.6 19 6.2 0.8 2.1 2 DUF6366 Family of unknown function (DUF6366) Domain annotation for each model (and alignments): >> DUF3899 Domain of unknown function (DUF3899) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 1.4e-05 0.12 3 63 .. 4 63 .. 3 70 .. 0.73 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.4e-05 DUF3899 3 ilFliglilliigvllivlragfFdgfaygfrrlkgqlfkakrkk.skkvdskldeqekkke 63 ++F + il++++++++v +a + + + +f r ++ k+ +++ ++ +++ +e + +k+ FUN_001030-T1 4 LSFCSSVILIVVILAFVVQEAYLVSPWGRRFGRSATK--KHRNERiRQVHSNEREETSHIKD 63 5899***********************9999996644..44444455555555555555554 PP >> DUF3653 Phage protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 2e-05 0.17 12 29 .. 19 36 .. 18 69 .. 0.76 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 2e-05 DUF3653 12 WrfdrdkLitPeGrrfsp 29 + +++++L++P Grrf FUN_001030-T1 19 FVVQEAYLVSPWGRRFGR 36 78999***********64 PP >> DUF6366 Family of unknown function (DUF6366) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.3 0.011 95 54 65 .. 10 21 .. 3 25 .. 0.71 2 ? 6.2 0.8 0.0022 19 6 31 .. 38 64 .. 35 66 .. 0.77 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.011 DUF6366 54 iLilviivgfii 65 ++++v+i++f++ FUN_001030-T1 10 VILIVVILAFVV 21 566677777776 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0022 DUF6366 6 etpeerRErLRq.eElkrnpsgnlnda 31 t + r Er+Rq +r+ +++++d+ FUN_001030-T1 38 ATKKHRNERIRQvHSNEREETSHIKDE 64 58899*******655667788888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (71 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1147 (0.0449012); expected 510.9 (0.02) Passed bias filter: 762 (0.0298297); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 726.24 // Query: FUN_001031-T1 [L=263] Description: FUN_001031 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-09 37.1 0.0 6.1e-09 36.5 0.0 1.3 1 SEA SEA domain Domain annotation for each model (and alignments): >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.0 2.4e-13 6.1e-09 2 78 .. 43 117 .. 42 131 .. 0.93 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 2.4e-13 SEA 2 yytgsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspe.kgsvvvdvvlvfrfpst 78 ++++++k++n +y+e+l+np+S++f +l+ ++e + +++ +k +i+++ l++s+ +g+ +v + l+f+++ t FUN_001031-T1 43 VFNVTLKLPNATYDESLANPHSPQFIKLRTDFEVGILQVYDG---YKPFIGVTTLKFSQApDGKAIVLFCLEFSNNGT 117 69****************************************...***************99***********99844 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (263 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 752 (0.0294382); expected 510.9 (0.02) Passed bias filter: 376 (0.0147191); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2603.29 // Query: FUN_001032-T1 [L=364] Description: FUN_001032 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-34 120.3 24.7 1.3e-34 120.3 24.7 1.8 2 7tm_1 7 transmembrane receptor (rhodopsin family) 3.4e-09 36.9 23.4 7.3e-08 32.5 23.3 2.4 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw ------ inclusion threshold ------ 0.63 10.6 7.4 0.18 12.4 3.2 2.3 2 DUF6170 Family of unknown function (DUF6170) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.5 0.17 1.4e+03 133 165 .. 12 37 .. 2 40 .. 0.48 2 ! 120.3 24.7 1.6e-38 1.3e-34 1 260 [] 41 310 .. 41 310 .. 0.92 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.17 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 133 keetvClidfpeeestwevsytlllsvlgfllp 165 ++ +C+++++ +++++++++l+ ++p FUN_001032-T1 12 CGAVICMFTYEV------RVIIVFFFTLT-FVP 37 566666666655......33333333333.334 PP == domain 2 score: 120.3 bits; conditional E-value: 1.6e-38 xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrt.ptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykr 95 gN+ + +ilr+k+lr+ +tn+ +l+L++a++l++l+++p+ +++ ++ g+wvfg + Cklv++++ ++l a i++l++i ++ +l+++ p++ FUN_001032-T1 41 GNCAFMSIILRQKHLRRsSTNFSILSLSFANVLITLICIPVFVLHIFILGKWVFGLIACKLVMFVQNLALNAVIFTLVIIGVEKFLVVHFPFHV-- 134 89999***********9899***************************99*********************************************.. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF 7tm_1 96 irtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.. 189 + ++++++ l+l+ W+l+++ s + l ++++++ +++ C d+p+ + +++++++ + ++pl++++ +++ ++ +++++ ++++ FUN_001032-T1 135 RSQRTKVRYLVLGGWILGIIQSSVYLSYRTVREI---NGVPYCIEDWPS--FKTRQIFNVVQAIALRFVPLTFMICLHIVTILKIKARMRSRRAna 225 66888999*********************99988...99**********..448889999999999999***********9999999998888878 PP .............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .............kkkksarkerkalktllvvvvvfvlcwlPyfilllldsl.lkeceseklvetallitlllayvnsclNPiiY 260 + ++ ++++ka+ +l+vvv+v + + +Py +++++l +++ s +++ +++++++l ++nsc Pii+ FUN_001032-T1 226 eqddfdsishmvqVSPQALKTRKKAVVMLVVVVAVSAWTLFPYSAYICWRMLgATDSFSYFTSNVIYIVVMWLVFFNSCCHPIIF 310 88888888888874445555666*****************************888888889999999****************95 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 23.3 8.5e-12 7.3e-08 16 317 .. 45 326 .. 28 328 .. 0.74 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 8.5e-12 7TM_GPCR_Srw 16 fHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlmAliRtlvvknpl 111 f iiL +k++r ss+n + + +++++l +l+ i ++l+++i ++++ ++ ++ ++++++ ++ ++ v++ + ++lvv +p+ FUN_001032-T1 45 FMSIILRQKHLRRSSTNFSILSLSFANVLITLICIPVFVLHIFI--------LGKWVFGLIACKLVMFVQNLALNAVIFTLVIIGVEKFLVVHFPF 132 6679999*****************************99944444........4789999999999******************************* PP 7TM_GPCR_Srw 112 snkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifllidgilskiipsil 207 + + q ++ ++ +++ ++ +i+++ y++y+ v e + + C e++ +++++ +if+++++i ++++p FUN_001032-T1 133 HVRSQ-----RTKVRYLVLGGWILGIIQSSVYLSYRTVREING-V--PYCI-------EDWPSFKTR-----------QIFNVVQAIALRFVPLTF 202 **988.....444555555555666667777777776644433.2..3585.......344454444...........567777777777777777 PP 7TM_GPCR_Srw 208 lpiltilLiieLrkakksrkklsksk...............kneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifsl 288 ++ l i+ i +++ +sr+ +++ +++++ LV+++++s + +p+ + + +++ ++s ++++ + +++ + FUN_001032-T1 203 MICLHIVTILKIKARMRSRRANAEQDdfdsishmvqvspqaLKTRKKAVVMLVVVVAVS-AWTLFPYSAYICWRMLGATDSFSYFTSNVIYIVVMW 297 77777777777776666665555333344455556666653333444445566666655.5678****9999999988878777777777788889 PP 7TM_GPCR_Srw 289 lltinsisHflicllmSsqYRktvkklfg 317 l+ +ns++H +i+ lmSs+YRk++k ++ FUN_001032-T1 298 LVFFNSCCHPIIFGLMSSEYRKAAKGALS 326 ************************98776 PP >> DUF6170 Family of unknown function (DUF6170) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 3.2 2.1e-05 0.18 3 77 .. 29 108 .. 27 122 .. 0.82 2 ? -2.0 0.1 0.61 5.2e+03 51 63 .. 252 264 .. 231 277 .. 0.61 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.1e-05 DUF6170 3 fyfstrhipalkg....lplaervkrldqaakkltvpektllnilkllvivpvfvlilqtasnwtsllwa.llvfllypl 77 f+f+ +p+l g + + r k+l +++ ++++ ++ n+l l+ +pvfvl + +w l a lv+++ l FUN_001032-T1 29 FFFTLTFVPSLVGncafMSIILRQKHLRRSSTNFSILSLSFANVLITLICIPVFVLHIFILGKWVFGLIAcKLVMFVQNL 108 899999999999844445678899****************************************8655551566666555 PP == domain 2 score: -2.0 bits; conditional E-value: 0.61 DUF6170 51 vfvlilqtasnwt 63 v+++++ + s wt FUN_001032-T1 252 VMLVVVVAVSAWT 264 3333334445555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (364 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1275 (0.0499119); expected 510.9 (0.02) Passed bias filter: 449 (0.0175768); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3494.64 // Query: FUN_001033-T1 [L=412] Description: FUN_001033 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-13 49.6 0.1 2e-06 28.4 0.0 2.8 3 fn3 Fibronectin type III domain ------ inclusion threshold ------ 0.021 15.7 0.1 0.61 10.9 0.0 2.6 2 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 0.038 15.1 0.0 0.25 12.4 0.0 2.3 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 0.44 3.7e+03 15 38 .. 14 44 .. 4 80 .. 0.54 2 ! 28.4 0.0 2.3e-10 2e-06 2 67 .. 126 202 .. 125 222 .. 0.76 3 ! 17.9 0.0 4.3e-07 0.0036 18 81 .. 255 338 .. 242 341 .. 0.80 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.44 fn3 15 sltvsWtpp..dgngpit..gYev...eyrp 38 ++++ W+p ++ + ++ Y+v +y p FUN_001033-T1 14 TVNIIWEPLpqEPTSFLEpvYYRVffcTYAP 44 5666677764322222225566664444444 PP == domain 2 score: 28.4 bits; conditional E-value: 2.3e-10 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpknetvpgsr.ets.......vtltgLkpgteYevrVq 67 +P+n++v++ + +l++sW+p+ +p+ Y++ y+ ++ + ++s+ ts +t+++L p+t+Y + +q FUN_001033-T1 126 KPQNVKVIAKGKRKLSISWNPSwemGRYAPFLCYRIWYSSSQAKRNESIlMTShpqefltYTIHDLSPHTKYALFIQ 202 7**********************876689999****999966644444442222334666************88776 PP == domain 3 score: 17.9 bits; conditional E-value: 4.3e-07 fn3 18 vsWtpp...dgngpitgYeveyrp...kne...............tvpgsretsvtltgLkpgteYevrVqavngaGegeesepl 81 v W+ p ++ng ++ ++++y++ k e ++++ +++++tl gL +Ye ++ n++G g+ s pl FUN_001033-T1 255 VFWKLParnTWNGVLRMFKIYYWQlpsK-EnfsnmnwdsnrsrmlQINDGSAKEATLIGLSRFDDYEAKISMCNSQGCGPNSGPL 338 6699999999**************7642.2578555554455555554444778**************************99987 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 7.2e-05 0.61 19 63 .. 155 202 .. 146 204 .. 0.69 2 ? 1.6 0.0 0.061 5.2e+02 39 70 .. 300 331 .. 265 335 .. 0.73 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 7.2e-05 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgee..ewilvsnn.keqeklviedLkpatwYelkvt 63 p l +++ y +++ + e il++++ +e +++i+dL+p t+Y l ++ FUN_001033-T1 155 PFLCYRIWYSSSQAKrnESILMTSHpQEFLTYTIHDLSPHTKYALFIQ 202 66778888877554311555555441555699************9876 PP == domain 2 score: 1.6 bits; conditional E-value: 0.061 FN3_DSCAM-DSCAML_C 39 snnkeqeklviedLkpatwYelkvtAhneaGs 70 n+ ++++ ++ +L+ Ye k++ +n+ G+ FUN_001033-T1 300 INDGSAKEATLIGLSRFDDYEAKISMCNSQGC 331 2445678899999***************9997 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 2.9e-05 0.25 1 75 [. 127 198 .. 127 211 .. 0.83 2 ? -1.4 0.0 0.61 5.2e+03 41 75 .. 288 320 .. 254 330 .. 0.63 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.9e-05 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtp.e.attspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYy 75 P++v++ +g ++ +++sW+++ e +p++ y+ +s+++++ + ++ +t ++++ ++t+++L+p t+Y FUN_001033-T1 127 PQNVKVIAKG-KRKLSISWNPSwEmGRYAPFLCYRIWYSSSQAKRNESIL-MT---SHPQEFLTYTIHDLSPHTKYA 198 7888888888.9999******973355889*******9998888776665.43...469*****************7 PP == domain 2 score: -1.4 bits; conditional E-value: 0.61 Pur_ac_phosph_N 41 statatsstyttedl...tsgyihsatltgLepgttYy 75 +++++ s + ++g +atl gL+ Y+ FUN_001033-T1 288 MNWDSNRSR-----MlqiNDGSAKEATLIGLSRFDDYE 320 222222222.....123367777777777777777775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (412 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 936 (0.0366412); expected 510.9 (0.02) Passed bias filter: 770 (0.0301429); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 4093.97 // Query: FUN_001034-T1 [L=582] Description: FUN_001034 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-12 47.9 0.4 1.8e-06 28.5 0.1 2.7 2 fn3 Fibronectin type III domain 3.1e-07 31.2 0.1 1.5e-06 29.1 0.1 2.2 1 Ig_3 Immunoglobulin domain 2.5e-06 28.2 0.3 1.1e-05 26.2 0.1 2.2 2 ig Immunoglobulin domain 1.3e-05 25.8 0.0 4.4e-05 24.1 0.0 1.9 1 Ig_2 Immunoglobulin domain 4.3e-05 24.0 0.0 0.00011 22.7 0.0 1.6 1 I-set Immunoglobulin I-set domain 0.0033 18.3 0.0 0.0091 16.9 0.0 1.7 1 Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 e ------ inclusion threshold ------ 0.12 13.0 0.1 8.3 7.1 0.0 3.1 3 V-set Immunoglobulin V-set domain Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 2.3e-06 0.0084 2 69 .. 261 338 .. 260 350 .. 0.76 2 ! 28.5 0.1 5e-10 1.8e-06 5 82 .. 372 466 .. 365 467 .. 0.83 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 2.3e-06 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpit...gYeveyrpkne....tvpgsr..etsvtltgLkpgteYevrVq.av 69 +P n++ +vts ++++ W++p d + +Y + ++ +++ tv+ s+ s+ + +L+p+ Y+v+++ +v FUN_001034-T1 261 KPDNIRTMNVTSRTFSFVWDAPkdmDDL---EaslHYLLVITAADTsqnkTVDLSKkvNLSHSFIKLRPYALYHVYIAcSV 338 799*******************844323...3355999988887666677555555555569999***********98544 PP == domain 2 score: 28.5 bits; conditional E-value: 5e-10 fn3 5 nltvt.dvtstsltvsWtpp...dgngpitgYeveyrpkne...............tvpgsr.etsvtltgLkpgteYevrVqavngaGegeesep 80 n+++t + ++ ++Wt p ++ng+it++ ++y+ +ne + t+ +lt+L ++++Y v++q ++ G g+ s+ FUN_001034-T1 372 NMKFTvHGKYRDVGLKWTLPntdTWNGRITHFVLHYKVANEseataepiagqvkvlSI---VsNTTGNLTDLWANETYAVTIQMCTRVGCGPVSQA 464 788875666666***********9**************99999999977776644422...256789*************************9998 PP fn3 81 le 82 ++ FUN_001034-T1 465 IY 466 75 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.1 0.1 4.1e-10 1.5e-06 8 78 .] 35 103 .. 31 103 .. 0.85 Alignments for each domain: == domain 1 score: 29.1 bits; conditional E-value: 4.1e-10 Ig_3 8 psstvveegesvtLtCeaegnppp..titWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 + v +g ++tL+Ce++g+ +++W++ng l++ + + ++ + +L i+++++++ G Y+C + N FUN_001034-T1 35 APVVYVISGTDLTLNCEINGSIILtdQVSWKHNGVWLHNLTNR----VDRKLQLVIPRIHEQQHGVYQCSVFN 103 4556699***********77765556*********87776666....9*********************9977 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.1 2.9e-09 1.1e-05 2 74 .. 37 105 .. 36 109 .. 0.93 2 ? -3.9 0.0 7 2.5e+04 26 40 .. 508 522 .. 505 534 .. 0.62 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 2.9e-09 ig 2 tvtvleGesatLtCsas.egspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpg 74 v+v G+ +tL+C+++ + +v+W+++g +++ + + + +l i++ e+++G Y C v n + FUN_001034-T1 37 VVYVISGTDLTLNCEINgSIILTDQVSWKHNGVWLHNLTN-----RVDRKLQLVIPRIHEQQHGVYQCSVFNVS 105 58999************999***************99977.....*************************9976 PP == domain 2 score: -3.9 bits; conditional E-value: 7 ig 26 vtWskegktkieslk 40 + ++k++ ++++s+ FUN_001034-T1 508 IYFWKKKPRPKNSRL 522 567777777777665 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 1.2e-08 4.4e-05 11 72 .. 40 108 .. 30 112 .. 0.78 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 1.2e-08 Ig_2 11 vtegesvtLtCsas..gnppakytwykdgkvlsssqn.......fftsnvsaedsGtYtCtarntkggkvs 72 v g+++tL+C++ + +++w ++g l + +n ++++++++++ G+Y+C++ n ++k+s FUN_001034-T1 40 VISGTDLTLNCEINgsIILTDQVSWKHNGVWLHNLTNrvdrklqLVIPRIHEQQHGVYQCSVFN--VSKQS 108 57899*******9965344699*******888877777777887889**************988..66666 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 2.9e-08 0.00011 10 81 .. 38 107 .. 31 111 .. 0.84 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 2.9e-08 I-set 10 vevkeGesaeleckvsGe..pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsage 81 v v G++++l+c++ G+ + +vsW+++g l++ ++ + + +L+I ++ +++ G Y+c + n +++ FUN_001034-T1 38 VYVISGTDLTLNCEINGSiiLTDQVSWKHNGVWLHN----LTNRVDRKLQLVIPRIHEQQHGVYQCSVFNVSKQ 107 66889************9666889***********6....333444578*******************997655 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 2.5e-06 0.0091 5 65 .. 41 109 .. 38 118 .. 0.76 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 2.5e-06 Ig_5 5 isgttVtltCpeese....eeikWekndkelkd.....keekeLvlenFsevedsGyysCykesskkakh 65 isgt+ tl+C + + ++++W++n+ l++ ++ +Lv+ e ++ G y+C+ + +k+++ FUN_001034-T1 41 ISGTDLTLNCEINGSiiltDQVSWKHNGVWLHNltnrvDRKLQLVIPRIHE-QQHGVYQCSVFNVSKQSV 109 9*********988655666********876655333334455788899999.899*****9988777544 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.11 4.1e+02 5 23 .. 37 55 .. 33 68 .. 0.74 2 ? 7.1 0.0 0.0023 8.3 71 108 .. 80 120 .. 71 121 .. 0.76 3 ? -0.9 0.0 0.73 2.7e+03 14 65 .. 496 542 .. 484 551 .. 0.66 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.11 V-set 5 evtvaeGesvtLtCslsss 23 +v v G+++tL+C+++ s FUN_001034-T1 37 VVYVISGTDLTLNCEINGS 55 577889********99987 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0023 V-set 71 sdfsltiqnltlsDsGtYtCav..ipkgevv.fgkgtrLtV 108 +++l i +++++ G+Y+C+v ++k++v+ ++ ++tV FUN_001034-T1 80 RKLQLVIPRIHEQQHGVYQCSVfnVSKQSVNlLPRDANVTV 120 5678999999************8755555554777777776 PP == domain 3 score: -0.9 bits; conditional E-value: 0.73 V-set 14 vtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekkkgrfslr 65 + L C+ls + + + W ++p+ ++++l++ + k++ +++++ ++ r FUN_001034-T1 496 IILLCVLSAF----IAIYFWKKKPRP-KNSRLLLSEVIKDKDTSPSPLYEMR 542 6677877766....555667777776.7777777777777776666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (582 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 730 (0.028577); expected 510.9 (0.02) Passed bias filter: 621 (0.02431); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.44 # Mc/sec: 5364.73 // Query: FUN_001035-T1 [L=417] Description: FUN_001035 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.15 12.1 0.0 0.2 11.6 0.0 1.2 1 DUF6082 Family of unknown function (DUF6082) 0.17 11.9 0.0 0.25 11.3 0.0 1.1 1 DUF6377 Domain of unknown function (DUF6377) Domain annotation for each model (and alignments): >> DUF6082 Family of unknown function (DUF6082) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 1.6e-05 0.2 12 55 .. 350 392 .. 340 412 .. 0.82 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.6e-05 DUF6082 12 savlsglalagvavslllqarqarrarlaeqrrlhfeLlkkAid 55 v++++al++v+ ++ +++ ++ ra+ + q++l+ +L + +d FUN_001035-T1 350 VFVAAAVALTAVSCAVYFRQ-KQNRAKKKRQEDLMNQLNAMNLD 392 458999***********999.888899999********999998 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 2e-05 0.25 59 121 .. 330 392 .. 323 405 .. 0.74 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2e-05 DUF6377 59 ekayqekeekqkrkllillilisvllllllvllviiykqlkklkkarkelkeaneqlkelnee 121 ekay ++++q + + ++i++++ +++l+++ + +y + k+ ++++k+ ++ +ql+++n + FUN_001035-T1 330 EKAYILQTKSQISGTEAFIIVFVAAAVALTAVSCAVYFRQKQNRAKKKRQEDLMNQLNAMNLD 392 678888888898888888888888888888777777766666666666645557888888654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (417 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1329 (0.0520258); expected 510.9 (0.02) Passed bias filter: 1075 (0.0420826); expected 510.9 (0.02) Passed Vit filter: 103 (0.0040321); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.42s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 4163.05 // Query: FUN_001036-T1 [L=473] Description: FUN_001036 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-06 26.8 1.8 0.046 14.4 0.0 3.7 3 fn3 Fibronectin type III domain Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.0 0.0 0.0032 82 30 66 .. 55 105 .. 47 115 .. 0.77 2 ! 5.3 0.2 0.0013 32 2 70 .. 150 222 .. 149 232 .. 0.68 3 ! 14.4 0.0 1.8e-06 0.046 16 80 .. 275 357 .. 260 360 .. 0.76 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.0032 fn3 30 tgYeveyrpkne.............tvpgsr.etsvtltgLkpgteYevrV 66 +Y v+y++ ++ ++g + ++++t+t+L+ g++ +++ FUN_001036-T1 55 VQYDVQYYTNSTyscdsqynrgnviALDGCHfTHNHTVTKLNSGRSLDCTI 105 57999999855576767777777777777779999********99876666 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0013 fn3 2 aPtnltvtdvtstsltvsWtppdgngpitgYeveyrpkne...tvpgsr...etsvtl.tgLkpgteYevrVq.avn 70 +P+ ++vt+ ++t sW++ g+g+ v + + n+ t+++ +++ t+ + p teY+++V av FUN_001036-T1 150 QPRSFQVTATKRREVTASWEHQ-GQGTCV---VMLDNHNGameTCTKRYiydQEKITFnNSVMPWTEYSLTVCcAVQ 222 699999*9999999******99.666543...444444444555555556667777776667788888887775555 PP == domain 3 score: 14.4 bits; conditional E-value: 1.8e-06 fn3 16 ltvsWtppdgngpitgYev....eyrp.kne............tvpgsr...etsvtltgLkpgteYevrVqavngaGegeesep 80 +t++Wt+ d + + g+ v ++r + + +p++ s+t+++L ++Y+ +V+ +++G g+ se FUN_001036-T1 275 VTLTWTAND-KQVWNGFPVastiTVRSiA-QekfdfpvinlsvPLPQDYsgsLVSYTIHNLAVEETYRASVKFCSNGGCGPASEA 357 789999992.4555588886666555543.2467888887766444443555677*************************99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (473 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 942 (0.0368761); expected 510.9 (0.02) Passed bias filter: 561 (0.0219612); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4738.49 // Query: FUN_001037-T1 [L=90] Description: FUN_001037 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (90 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 607 (0.023762); expected 510.9 (0.02) Passed bias filter: 448 (0.0175377); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 891.95 // Query: FUN_001037-T2 [L=77] Description: FUN_001037 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (77 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 587 (0.0229791); expected 510.9 (0.02) Passed bias filter: 518 (0.0202779); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 764.23 // Query: FUN_001038-T1 [L=263] Description: FUN_001038 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-15 57.2 0.1 2.3e-15 57.0 0.1 1.1 1 AIG1 AIG1 family 8.2e-06 26.4 0.0 1.4e-05 25.7 0.0 1.4 1 MMR_HSR1 50S ribosome-binding GTPase 0.0017 18.6 0.6 0.0045 17.2 0.4 1.8 2 nSTAND3 Novel STAND NTPase 3 0.0025 18.0 0.1 0.0041 17.3 0.1 1.3 1 Guanylate_kin Guanylate kinase 0.0026 18.1 0.2 0.0073 16.6 0.1 1.7 2 RsgA_GTPase RsgA GTPase 0.0093 15.8 0.1 0.015 15.1 0.1 1.2 1 Septin Septin ------ inclusion threshold ------ 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 Sigma54_activat Sigma-54 interaction domain 0.02 15.3 0.1 0.061 13.7 0.1 1.8 1 Tap-RNA_bind Tap, RNA-binding 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 ATPase KaiC 0.034 14.2 0.0 2.8 8.0 0.0 2.3 2 DUF3053 Protein of unknown function (DUF3053) 0.047 13.6 0.0 0.076 13.0 0.0 1.3 1 TniB Bacterial TniB protein 0.053 13.8 3.2 1.2 9.4 1.1 2.9 2 PduV-EutP Ethanolamine utilisation - propanediol utili 0.063 13.8 0.0 0.12 12.9 0.0 1.5 1 Dynamin_N Dynamin family 0.085 13.6 0.1 0.16 12.7 0.1 1.4 1 Roc Ras of Complex, Roc, domain of DAPkinase 0.094 12.6 0.1 0.17 11.7 0.1 1.4 1 STALD Sir2- and TIR-associating SLOG family 0.12 13.5 0.0 0.19 12.8 0.0 1.3 1 ABC_tran ABC transporter Domain annotation for each model (and alignments): >> AIG1 AIG1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.0 0.1 1.5e-18 2.3e-15 1 146 [. 25 179 .. 25 242 .. 0.83 Alignments for each domain: == domain 1 score: 57.0 bits; conditional E-value: 1.5e-18 AIG1 1 lrivLvGktgnGkSaTgNsilgkkaFesklsaqsvtkkcqkesrtwdg.......kkinViDTPglfdlsvsaeeiskeivrclll..aeegihal 87 ++i+++G+tg+Gk + +N ilg++ + + +svt+++++ +++++ +i+++DT g + + ++ i kei++ +++ a++ ih + FUN_001038-T1 25 RNIIILGRTGTGKKTIANKILGDERLQVDSAMTSVTREVRRMKAEEKVddtnsmhYIIKIVDTLGPYSKKIDKAWILKEISEHCNCtgACDEIHLI 120 59***********************************99887773332124444468***********************864433125677**** PP AIG1 88 llvlslgriteeeekalktlkelFgekilkylivvftrkddleddsledylsesspeaL 146 l+ ++ g ++++e ++ ++ el+ ++i k +v+t+ ++l +++ + +e s e++ FUN_001038-T1 121 LFTFRYGVYEQREIDIFTAICELYPDDIPKISALVITGCESLDEEGRNSLCQELSTETI 179 ******************************************99986655555554444 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 8.7e-09 1.4e-05 2 81 .. 27 122 .. 26 154 .. 0.71 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 8.7e-09 MMR_HSR1 2 vaivGrpNvGKStLinaltgk.kaiv.sdypgtTrdpnegklelkgkk.......ielvDtpGliegaseeeglerafla.......ieeadlill 81 ++i+Gr+ +GK t+ n+++g+ + +v s + +Tr++ + k e k ++ i++vDt G + ++ ++ + +++++ +e +lil+ FUN_001038-T1 27 IIILGRTGTGKKTIANKILGDeRLQVdSAMTSVTREVRRMKAEEKVDDtnsmhyiIKIVDTLGPYSKKIDKAWILKEISEhcnctgaCDEIHLILF 122 89******************97888879999********9999443335678888********544333333455544442333333334455555 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.4 2.8e-06 0.0045 16 119 .. 23 133 .. 17 173 .. 0.67 2 ? -1.4 0.0 1.5 2.3e+03 39 70 .. 184 215 .. 165 240 .. 0.74 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 2.8e-06 nSTAND3 16 knkvviitGepGiGKttlaemLalklldegy.evvki.ssi..eelekvl.dpnkkq.vflfDDflGetslekksknedskllsfikrirksknk. 104 +++ +ii+G +G+GK t+a+ ++ + + + + + +++ ++e+ + d+n+ ++ + D lG s + ++ ++++++++ + FUN_001038-T1 23 QKRNIIILGRTGTGKKTIANKILGDERLQVDsAMTSVtREVrrMKAEEKVdDTNSMHyIIKIVDTLGPYSKKIDKAWILKEISEHCNCTGACDEIh 118 4567899**************998877753212233333331123334441344333699999999997776666655666666665543333332 PP nSTAND3 105 klilTtReyilnqak 119 +++T R +++q + FUN_001038-T1 119 LILFTFRYGVYEQRE 133 488899988888865 PP == domain 2 score: -1.4 bits; conditional E-value: 1.5 nSTAND3 39 lklldegyevvkissieelekvldpnkkqvfl 70 ++l+++g +v ++++++ +++++ ++v+ FUN_001038-T1 184 VQLMKKGIVPVGFPNLKDIKPAFREEYEKVIA 215 56667776666667777777777666555654 PP >> Guanylate_kin Guanylate kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.1 2.6e-06 0.0041 2 45 .. 24 67 .. 23 80 .. 0.91 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.6e-06 Guanylate_kin 2 rrplvllgpsgaGksslkkaLlselpekfgvsvshtTrpprkge 45 +r +++lg +g+Gk+++ +++l + + + ++++Tr+ r+ FUN_001038-T1 24 KRNIIILGRTGTGKKTIANKILGDERLQVDSAMTSVTREVRRMK 67 799************************************99754 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.1 4.6e-06 0.0073 102 137 .. 20 55 .. 2 67 .. 0.82 2 ? -1.7 0.0 1.9 3e+03 36 58 .. 173 195 .. 168 239 .. 0.59 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 4.6e-06 RsgA_GTPase 102 ellkgkttvllGqSGvGKStLinallpelelktgei 137 ++l+++ +++lG +G GK t+ n++l++++l++ + FUN_001038-T1 20 AALQKRNIIILGRTGTGKKTIANKILGDERLQVDSA 55 5699999********************999999765 PP == domain 2 score: -1.7 bits; conditional E-value: 1.9 RsgA_GTPase 36 efnlrlldrfLvlaeesgiepvi 58 e++++++++ +v+++++gi pv FUN_001038-T1 173 ELSTETITKPVVQLMKKGIVPVG 195 56666666666666666666653 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.1 9.3e-06 0.015 6 83 .. 26 102 .. 23 110 .. 0.75 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 9.3e-06 Septin 6 tlmvvGesglGkstlinslfetdlieerkieeasekikktveikkkkveieedgvklnltvvDtpg.fGdaidnskcwe 83 ++++ G++g+Gk t+ n ++ ++ + ++ ++ +++ ++k+++++ + + ++ + +vDt g + +id + + FUN_001038-T1 26 NIIILGRTGTGKKTIANKILGDERLQVDSAMTS--VTREVRRMKAEEKVDDTNSMHYIIKIVDTLGpYSKKIDKAWILK 102 89******************9988887644444..34444556666677777899*********886777887665555 PP >> Sigma54_activat Sigma-54 interaction domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 1.6e-05 0.026 17 44 .. 19 46 .. 5 62 .. 0.82 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.6e-05 Sigma54_activat 17 kvaksdlsvlitGesGtGKelvaraihe 44 +a ++ +++i+G +GtGK+++a++i FUN_001038-T1 19 MAALQKRNIIILGRTGTGKKTIANKILG 46 5677889*****************9965 PP >> Tap-RNA_bind Tap, RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 3.8e-05 0.061 7 27 .. 90 110 .. 80 120 .. 0.92 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.8e-05 Tap-RNA_bind 7 pyGkkydkewllnsiqslcsv 27 py kk dk+w+l++i+++c+ FUN_001038-T1 90 PYSKKIDKAWILKEISEHCNC 110 899****************85 PP >> ATPase KaiC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 2.9e-05 0.047 5 62 .. 10 67 .. 7 85 .. 0.84 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 2.9e-05 ATPase 5 IeglDeilkgGlpegrvvlisGepGtGKtifglqFlingaekygepgvfvtleetaed 62 IeglD ++ ++r + i G +GtGK +++ + l +++ + vt e + ++ FUN_001038-T1 10 IEGLDGCSDMAALQKRNIIILGRTGTGKKTIANKILGDERLQVDSAMTSVTREVRRMK 67 9******************************999888877777777777777766655 PP >> DUF3053 Protein of unknown function (DUF3053) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.036 58 6 39 .. 152 186 .. 149 189 .. 0.88 2 ? 8.0 0.0 0.0018 2.8 130 161 .. 200 231 .. 197 239 .. 0.86 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.036 DUF3053 6 vvllLagCgdkekeqRkAFiefLqntvirs.gvkl 39 +l ++gC+ ++e R+ + L + i++ +v+l FUN_001038-T1 152 SALVITGCESLDEEGRNSLCQELSTETITKpVVQL 186 57899******************999999877776 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0018 DUF3053 130 ddlkvvydkaydktVtapanaltrvipaaesl 161 +d+k+++ + y+k++ an+l+ ++++a++ FUN_001038-T1 200 KDIKPAFREEYEKVIASDANKLKDLVFNASES 231 69************************998654 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 4.7e-05 0.076 27 95 .. 17 86 .. 5 106 .. 0.74 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.7e-05 TniB 27 leapkkkrmpnlllvGdsnnGKstivekFarlhpaq.ke.edeeevpvvvvqappepdekrlyaaiLeaLe 95 +++ ++ +n+++ G++ +GK ti++k +++ q ++ + ++v ++a ++ d+++ ++ i++ + FUN_001038-T1 17 SDMAALQK-RNIIILGRTGTGKKTIANKILGDERLQvDSaMTSVTREVRRMKAEEKVDDTNSMHYIIKIVD 86 55555555.8*******************988876623313444569999999999999888888777655 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 1.1 0.00078 1.2 2 24 .. 25 48 .. 24 130 .. 0.69 2 ? 0.0 0.0 0.6 9.6e+02 13 27 .. 166 180 .. 156 189 .. 0.83 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00078 PduV-EutP 2 kkilliGkvgsGKttLtqalkg.e 24 ++i+++G++g+GK t+++++ g e FUN_001038-T1 25 RNIIILGRTGTGKKTIANKILGdE 48 689*************99987642 PP == domain 2 score: 0.0 bits; conditional E-value: 0.6 PduV-EutP 13 GKttLtqalkgeelk 27 G+ +L+q+l+ e+++ FUN_001038-T1 166 GRNSLCQELSTETIT 180 8999*****999886 PP >> Dynamin_N Dynamin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 7.4e-05 0.12 1 48 [. 27 74 .. 27 125 .. 0.65 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 7.4e-05 Dynamin_N 1 iavvGdqSsGKSsvlnaLlgeeilprgsgpvTrrplelqlgeeeease 48 i+++G++ GK ++ n +lg+e l ++s +++ + + +++ ee++ + FUN_001038-T1 27 IIILGRTGTGKKTIANKILGDERLQVDSAMTSVTREVRRMKAEEKVDD 74 789*******************99998887654444444444444442 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 0.0001 0.16 2 65 .. 27 89 .. 26 96 .. 0.84 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.0001 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaG 65 +++lG +g+GK +++++++ de + ++ ++v+ ++++ +++ +d++ ++ ++i Dt G FUN_001038-T1 27 IIILGRTGTGKKTIANKILGDERLQVDSAMTSVTREVRRMKAEEKV-DDTNSMHYIIKIVDTLG 89 89********************999999999999888888655555.45556678899999987 PP >> STALD Sir2- and TIR-associating SLOG family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 0.00011 0.17 141 208 .. 17 86 .. 6 88 .. 0.82 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00011 STALD 141 feiAkekgklvipigvTGyaakkiweevlgdiekylkea.sklkeeleklade.eadsdeliklvlkilk 208 ++A ++ +i +g TG k+i++++lgd + +++ a +++ e+++++ e + d+++ ++ ++ki++ FUN_001038-T1 17 SDMAALQKRNIIILGRTGTGKKTIANKILGDERLQVDSAmTSVTREVRRMKAEeKVDDTNSMHYIIKIVD 86 5788999999*********************988888888999999999975515566778899999987 PP >> ABC_tran ABC transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.00012 0.19 11 44 .. 24 57 .. 18 107 .. 0.77 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00012 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF ABC_tran 11 gevlalvGenGaGKStLlkllagllkpteGeill 44 + + ++G++G+GK t+++ ++g ++ + ++ FUN_001038-T1 24 KRNIIILGRTGTGKKTIANKILGDERLQVDSAMT 57 56789*******************9987766533 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (263 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1120 (0.0438442); expected 510.9 (0.02) Passed bias filter: 894 (0.0349971); expected 510.9 (0.02) Passed Vit filter: 107 (0.00418869); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.29u 0.44s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 2531.17 // Query: FUN_001039-T1 [L=289] Description: FUN_001039 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-24 85.2 1.7 7.4e-24 84.7 1.7 1.2 1 AIG1 AIG1 family 3e-08 34.3 0.4 6.7e-08 33.1 0.2 1.7 2 MMR_HSR1 50S ribosome-binding GTPase 1.9e-06 28.5 2.3 0.00064 20.3 2.3 3.1 1 Dynamin_N Dynamin family 0.00016 22.1 0.0 0.00028 21.2 0.0 1.4 1 RsgA_GTPase RsgA GTPase 0.00042 21.4 0.1 0.0015 19.7 0.0 1.8 2 ABC_tran ABC transporter 0.00078 19.3 0.4 0.0015 18.4 0.4 1.4 1 Septin Septin 0.0023 18.1 0.4 0.0086 16.3 0.2 1.9 2 nSTAND3 Novel STAND NTPase 3 0.0033 17.6 1.8 0.0081 16.4 1.8 1.7 1 AAA_24 AAA domain 0.0034 17.4 0.2 0.0062 16.6 0.2 1.4 1 FeoB_N Ferrous iron transport protein B ------ inclusion threshold ------ 0.013 14.7 0.1 0.021 14.0 0.1 1.3 1 P-loop_TraG TraG P-loop domain 0.017 15.9 0.2 0.033 15.0 0.2 1.6 1 AAA_22 AAA domain 0.018 16.0 0.0 0.03 15.3 0.0 1.5 1 AAA_16 AAA ATPase domain 0.03 14.3 0.5 0.097 12.6 0.1 1.9 2 FtsK_SpoIIIE FtsK/SpoIIIE family 0.033 14.2 0.1 0.062 13.3 0.1 1.4 1 AAA_7 P-loop containing dynein motor region 0.034 14.2 0.9 0.21 11.6 0.1 2.4 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.037 15.0 0.5 0.075 14.0 0.2 1.7 2 AAA_18 AAA domain 0.045 14.0 0.0 0.093 13.0 0.0 1.4 1 AAA_29 P-loop containing region of AAA domain 0.058 14.1 0.1 0.15 12.8 0.1 1.8 1 Roc Ras of Complex, Roc, domain of DAPkinase 0.062 13.5 0.2 0.16 12.2 0.1 1.6 1 DEAD DEAD/DEAH box helicase 0.074 13.4 0.0 0.21 12.0 0.0 1.7 1 CSN7a_helixI COP9 signalosome complex subunit 7a helix I 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 TniB Bacterial TniB protein 0.1 12.8 1.3 0.17 12.1 0.1 1.9 2 Sigma54_activat Sigma-54 interaction domain 0.11 12.8 2.7 1.2 9.4 0.2 2.7 3 NACHT NACHT domain 0.11 13.3 0.0 0.16 12.8 0.0 1.4 1 AAA_33 AAA domain 0.21 11.7 3.6 7.7 6.6 0.1 2.4 2 SRP54 SRP54-type protein, GTPase domain 0.23 12.6 0.9 2 9.5 0.0 2.2 2 AAA_23 AAA domain 0.23 11.2 2.5 0.35 10.6 2.2 1.7 1 SLFN-g3_helicase Schlafen group 3, DNA/RNA helicase domain Domain annotation for each model (and alignments): >> AIG1 AIG1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.7 1.7 7.8e-27 7.4e-24 1 163 [. 66 234 .. 66 284 .. 0.74 Alignments for each domain: == domain 1 score: 84.7 bits; conditional E-value: 7.8e-27 AIG1 1 lrivLvGktgnGkSaTgNsilgkkaFesklsaqsvtkkcqkesr......twdgkkinViDTPglfdlsvsaeeiskeivrclll.aeegihalll 89 +++v+vGktg+GkS+ +N +lg + F k a+svt++++ + + ++ + ++iDT g+fd++++++++ +i+ ++ + egi+ +l+ FUN_001039-T1 66 RNVVVVGKTGAGKSTVANKVLGLEKFAVKNVANSVTSEVEARCStfydesSRTRYNFKIIDTLGVFDTKHKNDDVMTKIKTFFQKdSPEGINLVLF 161 589*********************************988765442100124445789***********************999872557******* PP AIG1 90 vlslgriteeeekalktlkelFgekilkylivvftrkddleddsledylsesspeaLkevlkecgnRvvlfnnk 163 v++ gr+t+ee+ ++ + F ++i ++ +v+t + d +++ ++ + +++++ +++ + ++ FUN_001039-T1 162 VFRKGRFTAEERRTFDYIIGNFSDQISDFSALVLTCCEGQTDAANQEFHAS-FQREARRIVSFMKKGIYMVGFP 234 ***********************************9998888887887774.4455778887777654443332 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.2 7.1e-11 6.7e-08 1 100 [. 67 179 .. 67 196 .. 0.69 2 ? -1.8 0.0 4.8 4.6e+03 87 92 .. 249 254 .. 200 270 .. 0.55 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 7.1e-11 MMR_HSR1 1 rvaivGrpNvGKStLinaltgk.kaivsdypgtTrdpnegkle..lkgkk.....ielvDtpGliegaseeeglerafla.....iee.adlillv 82 +v++vG++ +GKSt+ n+++g k v++++ ++ +e +++ +++++ ++++Dt G++++++++ +++ ++++ e +l+l+v FUN_001039-T1 67 NVVVVGKTGAGKSTVANKVLGLeKFAVKNVANSVTSEVEARCStfYDESSrtrynFKIIDTLGVFDTKHKNDDVMTKIKTffqkdSPEgINLVLFV 162 599******************7699999999655555555555353332245555********876445555454444443334433357999999 PP MMR_HSR1 83 vdaeeglteldeeleell 100 +++ ++t+++++ +++ FUN_001039-T1 163 FRK-GRFTAEERRTFDYI 179 975.55777777666664 PP == domain 2 score: -1.8 bits; conditional E-value: 4.8 MMR_HSR1 87 egltel 92 e+++e+ FUN_001039-T1 249 EEIKEQ 254 223333 PP >> Dynamin_N Dynamin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 2.3 6.8e-07 0.00064 1 130 [. 68 255 .. 68 274 .. 0.85 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 6.8e-07 Dynamin_N 1 iavvGdqSsGKSsvlnaLlgeeilprgsgpvTrrplelql........................................................ 40 ++vvG++ +GKS+v n +lg e ++++ + + e++ FUN_001039-T1 68 VVVVGKTGAGKSTVANKVLGLE-KFAVKNVANSVTSEVEArcstfydessrtrynfkiidtlgvfdtkhknddvmtkiktffqkdspeginlvlfv 162 89*******************9.555567888899999999999**************************99999999999999999999999999 PP Dynamin_N 41 ...geeeeaseaavkvelkeeekkfedlselreeieketekiagenkgvseepivleilsllvpdltlvDlPGldsvakgdqelvkeyikkad 130 g+ ++ ++ ++ ++++ ++++d+s+l ++++ + +a++ s + + +i s+ ++++ +v P + + + + +++++e ik+++ FUN_001039-T1 163 frkGRFTAEERRTFDYIIGNFSDQISDFSALVLTCCEGQTDAANQEFHASFQREARRIVSFMKKGIYMVGFPDVSKMKPRMKQVMEEEIKEQA 255 998443343458899999999*********999999999999988888899999999999999999999999999999999988888884433 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.0 3e-07 0.00028 103 141 .. 62 100 .. 49 134 .. 0.79 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 3e-07 RsgA_GTPase 103 llkgkttvllGqSGvGKStLinallpelelktgeisekl 141 +++++ +v++G++G+GKSt n++l+ ++ +++++ ++ FUN_001039-T1 62 AVENRNVVVVGKTGAGKSTVANKVLGLEKFAVKNVANSV 100 5788999*******************99****9998765 PP >> ABC_tran ABC transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 1.5e-06 0.0015 5 42 .. 59 96 .. 55 160 .. 0.74 2 ? -0.9 0.0 3.4 3.2e+03 54 94 .. 221 263 .. 192 285 .. 0.50 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 1.5e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF ABC_tran 5 sltleegevlalvGenGaGKStLlkllagllkpteGei 42 +++ e++ +++vG++GaGKSt+++ ++gl+k + ++ FUN_001039-T1 59 EFQAVENRNVVVVGKTGAGKSTVANKVLGLEKFAVKNV 96 678889999********************998755555 PP == domain 2 score: -0.9 bits; conditional E-value: 3.4 xxxxxxxxxxxxxx..xxxxxxxx.xxxxxxxxxxxxxxxxxxx RF ABC_tran 54 lkslrkeigvvfqe..delfpelt.vrenekkaraeealeklgl 94 + ++k i +v ++++p+++ v e+e k++a e+l+k+ + FUN_001039-T1 221 VSFMKKGIYMVGFPdvSKMKPRMKqVMEEEIKEQA-EMLKKVVM 263 34444444444322235555555534444333333.33444443 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.4 1.6e-06 0.0015 6 88 .. 67 147 .. 64 157 .. 0.80 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 1.6e-06 Septin 6 tlmvvGesglGkstlinslfetdlieerkieeasekikktveikkkkveieedgvklnltvvDtpg.fGdaidnskcwepivey 88 +++vvG++g Gkst+ n ++ + + + +++ +++ve + ++ e ++ n+ ++Dt g f + n++ + i ++ FUN_001039-T1 67 NVVVVGKTGAGKSTVANKVLGLEKFAVK---NVANSVTSEVEARCSTFYDESSRTRYNFKIIDTLGvFDTKHKNDDVMTKIKTF 147 89****************9998877775...5556677889999999999999***********99344456666666666555 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.2 9.1e-06 0.0086 16 101 .. 64 154 .. 55 194 .. 0.68 2 ? -0.8 0.0 1.6 1.5e+03 96 128 .. 181 216 .. 163 226 .. 0.64 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 9.1e-06 nSTAND3 16 knkvviitGepGiGKttlaemLa..lklldegyevvkissieelekvl.dpnkkq..vflfDDflGetslekksknedskllsfikrirks 101 +n+ v+++G++G+GK+t+a+ ++ k++ +++ s++e + + d+++++ f + D lG + + k+ + +k+ +f ++ + + FUN_001039-T1 64 ENRNVVVVGKTGAGKSTVANKVLglEKFAVKNVANSVTSEVEARCSTFyDESSRTryNFKIIDTLGVFDTKHKNDDVMTKIKTFFQKDSPE 154 688999*************987532455556554444455554444442555444558999999999988888887778877777665444 PP == domain 2 score: -0.8 bits; conditional E-value: 1.6 nSTAND3 96 krirksknk.k.lilTtReyilnqakekse.klerl 128 +++++ + l+lT++e a+++++ +++r FUN_001039-T1 181 GNFSDQISDfSaLVLTCCEGQTDAANQEFHaSFQRE 216 445555555445899999998888888866455554 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 1.8 8.6e-06 0.0081 2 116 .. 65 226 .. 64 268 .. 0.80 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 8.6e-06 AAA_24 2 klkvliyGpsgiGKTtlaksl...pkplvldtekGskslegdkfpdir.......................swqdflelidel............. 58 ++ v+++G+ g GK+t a+++ +k +v ++ ++++s ++ + + +d++ +i+++ FUN_001039-T1 65 NRNVVVVGKTGAGKSTVANKVlglEKFAVKNVANSVTSEVEARCSTFYdessrtrynfkiidtlgvfdtkhKNDDVMTKIKTFfqkdspeginlvl 160 6789****************9999999999999999888888887776888888888866666666666665555555555559999********* PP AAA_24 59 .........aeelagyktlV...iDtvdklerlcleyickqsskaekiedkgdgkGygelkeefrrllda 116 aee ++++ ++ D +++++ l+l ++ q+ +a+++ +++++++ ++++++++++ FUN_001039-T1 161 fvfrkgrftAEERRTFDYIIgnfSDQISDFSALVLTCCEGQTDAANQE----FHASFQREARRIVSFMKK 226 *******************64448*******************97776....445577777777777765 PP >> FeoB_N Ferrous iron transport protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.2 6.6e-06 0.0062 2 72 .. 67 145 .. 66 160 .. 0.73 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 6.6e-06 FeoB_N 2 tvalvGnpnvGkttlfnaltgak....qkvgNwpGvtvekkegklklke....keielvDlPGiYslsalseeekvard 72 +v++vG+ +Gk+t+ n++ g + ++v+N ve + ++ ++ ++++++D+ G+++ ++ +++ + FUN_001039-T1 67 NVVVVGKTGAGKSTVANKVLGLEkfavKNVANSVTSEVEARCSTFYDESsrtrYNFKIIDTLGVFDTKHKNDDVMTKIK 145 689******************87433357888888888888888754322223789**********9988777555444 PP >> P-loop_TraG TraG P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.1 2.2e-05 0.021 24 51 .. 60 87 .. 49 156 .. 0.69 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.2e-05 P-loop_TraG 24 kgiitnrnkfilGpsGsGksfftnhlvr 51 + ++nrn +++G +G+Gks + n+++ FUN_001039-T1 60 FQAVENRNVVVVGKTGAGKSTVANKVLG 87 56799*******************9874 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.2 3.5e-05 0.033 6 30 .. 66 90 .. 62 162 .. 0.70 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 3.5e-05 AAA_22 6 gilvltGesGtGKTtllrrlleqld 30 + +v++G +G+GK+t+++++l + FUN_001039-T1 66 RNVVVVGKTGAGKSTVANKVLGLEK 90 679****************998753 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 3.2e-05 0.03 23 45 .. 64 86 .. 47 161 .. 0.81 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.2e-05 AAA_16 23 rpplvlvsGeaGvGKSalvrell 45 + ++v+v+G +G+GKS++++++l FUN_001039-T1 64 ENRNVVVVGKTGAGKSTVANKVL 86 3489***************9988 PP >> FtsK_SpoIIIE FtsK/SpoIIIE family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 0.0001 0.097 32 57 .. 59 83 .. 51 87 .. 0.83 2 ? -1.1 0.0 1.5 1.5e+03 146 146 .. 148 148 .. 92 233 .. 0.52 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.0001 FtsK_SpoIIIE 32 vldlkkmpghlliaGatgsGKSvaln 57 +++++++ +++++G tg+GKS++ n FUN_001039-T1 59 EFQAVENR-NVVVVGKTGAGKSTVAN 83 46667777.**************877 PP == domain 2 score: -1.1 bits; conditional E-value: 1.5 FtsK_SpoIIIE 146 f 146 f FUN_001039-T1 148 F 148 1 PP >> AAA_7 P-loop containing dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 6.5e-05 0.062 28 55 .. 60 87 .. 48 113 .. 0.74 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 6.5e-05 AAA_7 28 lllknkkpvLlvGptGtGKtviikdllk 55 + ++++v +vG+tG GK+++++++l FUN_001039-T1 60 FQAVENRNVVVVGKTGAGKSTVANKVLG 87 4566799****************99653 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 0.00023 0.21 3 34 .. 65 96 .. 63 136 .. 0.66 2 ? 0.4 0.1 0.61 5.8e+02 93 130 .. 188 226 .. 183 279 .. 0.58 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00023 GTP_EFTU 3 irnigiighvDhGKtTltdrllyktgaiskrg 34 rn++++g +GK+T++ ++l + k+ FUN_001039-T1 65 NRNVVVVGKTGAGKSTVANKVLGLEKFAVKNV 96 69******************995444433333 PP == domain 2 score: 0.4 bits; conditional E-value: 0.61 GTP_EFTU 93 lDgavlvvdaveGvepqteevlrlarklgvp.iivviNK 130 D+ lv+ + eG + ++ ++ +++ + i+ ++ K FUN_001039-T1 188 SDFSALVLTCCEGQTDAANQEFHASFQREARrIVSFMKK 226 577778888888888888888888887777755556655 PP >> AAA_18 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.2 7.9e-05 0.075 1 88 [. 68 171 .. 68 202 .. 0.61 2 ? -1.6 0.0 5.3 5e+03 77 77 .. 243 243 .. 164 270 .. 0.59 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 7.9e-05 AAA_18 1 IlitGtpGvGKttlareLserlgf............gdnvrdlakenglvlsddee..............tdeskrldedklaklldeleelasle 70 ++++G+ G+GK+t+a+ + + +f + e +++ +de +++k ++d++ k + +++ + FUN_001039-T1 68 VVVVGKTGAGKSTVANKVLGLEKFavknvansvtseV--------EARCSTFYDESsrtrynfkiidtlgVFDTKHKNDDVMTKIKTFFQKDS--P 153 789*************995555557766544344421........222222222223333334456666666666666777666666666664..4 PP AAA_18 71 eggnlvidghlaelfper 88 eg nlv+ ++ + f+ + FUN_001039-T1 154 EGINLVLFVFRKGRFTAE 171 777777777777666554 PP == domain 2 score: -1.6 bits; conditional E-value: 5.3 AAA_18 77 i 77 + FUN_001039-T1 243 M 243 2 PP >> AAA_29 P-loop containing region of AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 9.8e-05 0.093 21 39 .. 64 81 .. 55 86 .. 0.79 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 9.8e-05 AAA_29 21 dpkgatlltGpsGsGKSTl 39 + + +++++G++G+GKST+ FUN_001039-T1 64 E-NRNVVVVGKTGAGKSTV 81 2.3379************7 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.00015 0.15 2 66 .. 68 130 .. 67 176 .. 0.75 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00015 Roc 2 vvllGdsgvGKtsllkrfve.defdekekstigvdflskeltkikglendkklkkiklniWDtaGq 66 vv++G++g+GK++++++++ ++f k+ + + ++ ++ +++ ++++ ++++++i Dt G FUN_001039-T1 68 VVVVGKTGAGKSTVANKVLGlEKFAVKNVANSVTSEVEARC---STFYDESSRTRYNFKIIDTLGV 130 89***************997355655443322222222333...3334455667899999999885 PP >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 0.00017 0.16 11 31 .. 62 82 .. 55 100 .. 0.86 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00017 xxxxxxxxxxxxxxxxxxxxx RF DEAD 11 llegkdvlvqapTGsGKTlaf 31 + e+++v+v+++TG+GK++++ FUN_001039-T1 62 AVENRNVVVVGKTGAGKSTVA 82 4589**************997 PP >> CSN7a_helixI COP9 signalosome complex subunit 7a helix I domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.00022 0.21 19 41 .. 194 216 .. 188 219 .. 0.88 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00022 CSN7a_helixI 19 vLsciEtqverANaeknkaikhk 41 vL c E q++ AN+e+ + ++ FUN_001039-T1 194 VLTCCEGQTDAANQEFHASFQRE 216 9***************9988775 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.00021 0.2 32 96 .. 62 130 .. 52 152 .. 0.63 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00021 TniB 32 kkrmpnlllvGdsnnGKstivekFarlhpaqkeedee....evpvvvvqappepdekrlyaaiLeaLea 96 + + +n+++vG++ GKst+++k l++ ++ ++ ev+ +e++ +r +i+++L++ FUN_001039-T1 62 AVENRNVVVVGKTGAGKSTVANKVLGLEKFAVKNVANsvtsEVEARCSTFYDESSRTRYNFKIIDTLGV 130 556689****************99988876643333200003333333344566666666666666655 PP >> Sigma54_activat Sigma-54 interaction domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.00018 0.17 14 45 .. 57 88 .. 48 107 .. 0.78 2 ? -2.3 0.0 4.5 4.3e+03 7 38 .. 242 275 .. 237 284 .. 0.55 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00018 Sigma54_activat 14 kikkvaksdlsvlitGesGtGKelvaraihea 45 +++ a ++ +v++ G++G+GK++va+++ FUN_001039-T1 57 MAEFQAVENRNVVVVGKTGAGKSTVANKVLGL 88 45556677899***************998655 PP == domain 2 score: -2.3 bits; conditional E-value: 4.5 Sigma54_activat 7 alkelle.kikkvaksdlsvlitGe.sGtGKelv 38 ++k+++e +ik+ a++ +v+++ + + GKe++ FUN_001039-T1 242 RMKQVMEeEIKEQAEMLKKVVMKADkKCLGKEMF 275 5555543145555555555555443145566665 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.2 0.0013 1.2 2 20 .. 67 85 .. 66 94 .. 0.90 2 ? -1.7 0.0 3.4 3.2e+03 34 67 .. 157 188 .. 140 202 .. 0.67 3 ? 2.5 0.1 0.17 1.6e+02 16 44 .. 257 285 .. 255 286 .. 0.92 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.0013 NACHT 2 tvilqGeaGsGKTtLlqkl 20 v++ G++G GK+t + k+ FUN_001039-T1 67 NVVVVGKTGAGKSTVANKV 85 699*************997 PP == domain 2 score: -1.7 bits; conditional E-value: 3.4 NACHT 34 fklvFflslrelsrsgkalsladllfsqlpepaa 67 ++F+++ ++++ ++ ++ d++ ++ + + FUN_001039-T1 157 NLVLFVFRKGRFTAEE--RRTFDYIIGNFSDQIS 188 4678888888888876..4577777766666555 PP == domain 3 score: 2.5 bits; conditional E-value: 0.17 NACHT 16 LlqklalawaegklpqdafklvFflslre 44 +l+k+++++ +++l +++f+l+F+ ++r+ FUN_001039-T1 257 MLKKVVMKADKKCLGKEMFELTFWEKVRQ 285 589*********************98886 PP >> AAA_33 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.00017 0.16 2 35 .. 68 107 .. 68 213 .. 0.76 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00017 AAA_33 2 illvGlsGsGKstlarrlleelg......avllssDtlrk 35 +++vG G+GKst+a ++l a ++s ++ + FUN_001039-T1 68 VVVVGKTGAGKSTVANKVLGLEKfavknvANSVTSEVEAR 107 689*************996433344555556666666555 PP >> SRP54 SRP54-type protein, GTPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 1.4 0.022 21 3 22 .. 67 86 .. 65 97 .. 0.82 2 ? 6.6 0.1 0.0082 7.7 57 121 .. 93 160 .. 86 206 .. 0.68 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.022 SRP54 3 villvGlqGsGKTttiaKLa 22 +++vG +G+GK t + K+ FUN_001039-T1 67 NVVVVGKTGAGKSTVANKVL 86 5799************9975 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0082 SRP54 57 vpvikkkeeadpaavakeavekakeekidvvlvDTaGrlqtdkelmeelkkikkvl...kpdevllvl 121 v+ ++++ +++ a ++ ++ + ++++ ++DT G t+++ + ++kik++ +p+ + lvl FUN_001039-T1 93 VKNVANSVTSEVEARCSTFYDESSRTRYNFKIIDTLGVFDTKHKNDDVMTKIKTFFqkdSPEGINLVL 160 555555556666666777778888999**********9888888777777777777444666666665 PP >> AAA_23 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.0 0.0021 2 18 35 .. 64 81 .. 44 85 .. 0.77 2 ? 1.3 0.5 0.71 6.7e+02 73 149 .. 142 173 .. 94 277 .. 0.40 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0021 AAA_23 18 skgltlItGpNGsGKTTi 35 ++ ++++G++G+GK+T+ FUN_001039-T1 64 ENRNVVVVGKTGAGKSTV 81 5556799**********8 PP == domain 2 score: 1.3 bits; conditional E-value: 0.71 AAA_23 73 ayvklefenkdgkktytiererelskkkgktkkkeklelleidelqqfisellkrski..ilpllvflgqerreeefee 149 +++k f++++ i+ +l+ ++++r + ++e+ FUN_001039-T1 142 TKIKTFFQKDS----------------------------------------------PegINLVLFVFRKGR-FTAEER 173 22333332222..............................................222222223333333.222222 PP >> SLFN-g3_helicase Schlafen group 3, DNA/RNA helicase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 2.2 0.00037 0.35 3 74 .. 67 152 .. 65 263 .. 0.75 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00037 SLFN-g3_helicase 3 vvlveGgaGtGKsvvalnllaeleksdlkktanylsvNhplvlvlrealagde..............kkkikeafekltsfinqls 74 v+v G++G+GKs va+++l + ++ + + s ++ ++ + + +++ k+k ++ ++k+++f ++ s FUN_001039-T1 67 NVVVVGKTGAGKSTVANKVLGLEKFAVKNVANSVTSEVEARCSTFYDESSRTRynfkiidtlgvfdtKHKNDDVMTKIKTFFQKDS 152 6899***************9876445555555555556666677777776666666666667777767777777777777777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (289 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1372 (0.0537091); expected 510.9 (0.02) Passed bias filter: 823 (0.0322177); expected 510.9 (0.02) Passed Vit filter: 126 (0.00493247); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 27 [number of targets reported over threshold] # CPU time: 0.34u 0.43s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 2789.63 // Query: FUN_001040-T1 [L=406] Description: FUN_001040 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-24 84.7 0.0 6e-24 83.9 0.0 1.5 1 Abhydro_lipase Partial alpha/beta-hydrolase lipase region 5e-15 56.3 0.3 1e-14 55.3 0.1 1.5 2 Abhydrolase_1 alpha/beta hydrolase fold 4.9e-07 29.8 0.0 2.7e-06 27.4 0.0 1.9 2 Hydrolase_4 Serine aminopeptidase, S33 ------ inclusion threshold ------ 0.067 14.3 0.0 0.1 13.7 0.0 1.3 1 Abhydrolase_6 Alpha/beta hydrolase family 0.087 13.5 0.3 0.22 12.3 0.3 1.6 1 zf-CCCH_PARP12 PARP12-like CCCH zinc finger tandem Domain annotation for each model (and alignments): >> Abhydro_lipase Partial alpha/beta-hydrolase lipase region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.9 0.0 1.2e-27 6e-24 1 62 [. 41 102 .. 41 103 .. 0.98 Alignments for each domain: == domain 1 score: 83.9 bits; conditional E-value: 1.2e-27 Abhydro_lipase 1 vseiikkyGypveeheVtTeDGYiLtlhRipagrkksekkekkpvvllqHGLlasSeswvtn 62 vs++i++ Gypveeh+V TeD+++L ++Rip+gr +++++ +k+vv+lqHGLla+S++wv n FUN_001040-T1 41 VSQLIRSRGYPVEEHSVVTEDDFVLGVQRIPYGRAERSRRDPKHVVFLQHGLLADSSNWVQN 102 689*********************************************************98 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.3 0.1 2e-18 1e-14 2 97 .. 85 198 .. 84 228 .. 0.89 2 ? -2.4 0.0 0.84 4.3e+03 200 216 .. 319 357 .. 266 382 .. 0.63 Alignments for each domain: == domain 1 score: 55.3 bits; conditional E-value: 2e-18 Abhydrolase_1 2 pvlllHGlpgssdlwrk......lapaLakdgfrvialDlrGfGkSsrpkaq..............ddyrtddlaedlekildalglekvnlvGhS 77 +v l HGl++ s +w l++ La++g++v++ ++rG+ +S++ + ++ d+ ++le++l+ +g +++++vGhS FUN_001040-T1 85 VVFLQHGLLADSSNWVQnypddsLGYILADNGCDVWLGNVRGNRYSRHN--ChlapcepkfwdwsfQEMAAKDIPAMLEYVLNITGETQLYYVGHS 178 6899******99999999999*************************544..33599**********99**************************** PP Abhydrolase_1 78 lGGlialayaakypervkal 97 +G+li++ ++++ p+ k++ FUN_001040-T1 179 QGTLIGFIAFSTIPHIAKKV 198 ************97655544 PP == domain 2 score: -2.4 bits; conditional E-value: 0.84 Abhydrolase_1 200 e.....................ptlviwgeqDplvpp.q 216 e t +++g++D l + FUN_001040-T1 319 EgnlkhyhqdtppvyditkmttRTAFFYGGKDGLANAtD 357 355555555555555556666677778888888875533 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 5.3e-10 2.7e-06 2 118 .. 81 217 .. 80 238 .. 0.83 2 ? -0.1 0.0 0.13 6.6e+02 187 216 .. 336 365 .. 332 371 .. 0.85 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 5.3e-10 Hydrolase_4 2 epkavvvlvHGl.gehsgryae.....laeaLaaqGfavyalDhrGhGkse.........gkrghvpsfddyvdDlaafvekikeehpglplfllG 82 +pk vv+l HGl +++s+++++ l++ La++G +v+ + rG s +k ++++ + +D+ a++e + + +++l+ +G FUN_001040-T1 81 DPKHVVFLQHGLlADSSNWVQNypddsLGYILADNGCDVWLGNVRGNRYSRhnchlapcePKFWDWSFQEMAAKDIPAMLEYVLNITGETQLYYVG 176 6999*******73677777764222458999***************************************************************** PP Hydrolase_4 83 hSmG...GaiallylleypdkvkglilsaPalkikekv..a 118 hS G G+ia++++ + ++kvk + +aP + +++ + FUN_001040-T1 177 HSQGtliGFIAFSTIPHIAKKVKLFFALAPIFYLNHTSkfC 217 ****5555567777788888************999864443 PP == domain 2 score: -0.1 bits; conditional E-value: 0.13 Hydrolase_4 187 ekitvPllllhGgaDkvvdpagsrelyera 216 +k+t+ + +++Gg+D + + ++ r+l+ ++ FUN_001040-T1 336 TKMTTRTAFFYGGKDGLANATDVRALIPQI 365 678999************999998887665 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 2e-05 0.1 1 121 [. 85 238 .. 85 313 .. 0.63 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2e-05 Abhydrolase_6 1 vvlv.HGaglssssW..rl.vapLaallaag.vrvlapDlpGhGss.........dpppldlad....vadladlldelga..gggpvvlvGHSlG 76 vv++ HG+ ++ss W ++ ++L la+ + v+ +G s +p d++ + d+ + l+ + + g ++ vGHS G FUN_001040-T1 85 VVFLqHGLLADSSNWvqNYpDDSLGYILADNgCDVWLGNVRGNRYSrhnchlapcEPKFWDWSFqemaAKDIPAMLEYVLNitGETQLYYVGHSQG 180 79999**********7644555885555555599999999999522233333333555577777444447777777777778899999******** PP Abhydrolase_6 77 Gavala.......aa.lvag.vllappvaplgl....laallallaallaalaa.pawl 121 +++ a +v+ +lap ++ l ++l++ l++ +++++ +w FUN_001040-T1 181 TLIGFIafstiphIAkKVKLfFALAP-IFYLNHtskfCRDLARDLQPYEELFHPsGEWE 238 88666643344432244444888888.44444443332222222222222222233444 PP >> zf-CCCH_PARP12 PARP12-like CCCH zinc finger tandem # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.3 4.2e-05 0.22 14 37 .. 300 324 .. 298 328 .. 0.86 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 4.2e-05 zf-CCCH_PARP12 14 LHLCklfllgkCrf.kgrrkCkfsH 37 LH+C+ l gkC++ + r+ ++ H FUN_001040-T1 300 LHFCQIILAGKCQMfNYGREGNLKH 324 9************988888777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (406 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4082.22 // Query: FUN_001041-T1 [L=457] Description: FUN_001041 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.3e-160 533.2 12.2 8.2e-160 533.0 12.2 1.0 1 PPP1R32 Protein phosphatase 1 regulatory subunit 32 ------ inclusion threshold ------ 0.27 11.8 0.0 0.69 10.5 0.0 1.6 1 CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-termi Domain annotation for each model (and alignments): >> PPP1R32 Protein phosphatase 1 regulatory subunit 32 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 533.0 12.2 6.4e-164 8.2e-160 1 418 [] 1 444 [. 1 444 [. 1.00 Alignments for each domain: == domain 1 score: 533.0 bits; conditional E-value: 6.4e-164 PPP1R32 1 mgkLplGvvspyvkaSsgadtdplkFYatsYstaYgreeFkprtgkhvGtGYksNfrpavsyqasLdkldnpamGellrDnyesvtkksyrplevp 96 mg+Lp+G+ ++++++S+gad ++kFY+t+Yst Yg+e+F+pr+g+h+GtGY+sNfrp v+y+++Ld+ldnpa G+ll+Dny+s+tkk++ p++++ FUN_001041-T1 1 MGRLPYGPGNAHILQSKGADVGVMKFYCTEYSTGYGQEGFNPRIGHHSGTGYQSNFRPGVYYSRRLDELDNPALGKLLTDNYASITKKHFLPSKGS 96 9*********************************************************************************************** PP PPP1R32 97 dgkeplprsvhqte.sgfvrekpktlptskevkkvhfdtqdagpkaipglepkerplLhklqkkdslevenaryGprymssEynskykgeepsqrd 191 g +p++r +++t+ sgfv+++p t+p+s++v+ vh+dt+ +g +++p +r+lL++l++kd++++en +Gp yms+E + ++ g +p+qr+ FUN_001041-T1 97 SGIDPFSRGLYMTAaSGFVKDIPVTVPRSRQVRDVHIDTRAKG-----TVYPYHRSLLYTLKHKDPISRENGFHGPSYMSTESQINFPG-TPKQRM 186 *************99****************************.....*****************************************.****** PP PPP1R32 192 llqkktiGakEesGFteesnkePitfqpks...qalpgdlvlrP.GvsvtksdylpvetakGdeflpvlakgseretGfsr............... 268 +++kkt+G+kE sGFt+++n+ePitf+p++ ++++++ ++rP G+s++k d+lpve+ +G+e lp l++gser+tGf++ FUN_001041-T1 187 DTSKKTMGYKEGSGFTHAHNDEPITFNPMEayeGIRDPRWTHRPtGFSIMKKDFLPVEYIHGNEKLPILSHGSERNTGFTHgtkarpvfysklgqe 282 *****************************99999************************************************************** PP PPP1R32 269 ............ekekkrdpletrvmtskseksslshlqfqgkqrmdqsnsellgrekvGnkEltGfslNNdsyvesaedpdraerylTtynakyf 352 e++kk dp e+++m+++++ ss+++++f+gkqr+d s++e+lg+ ++G kEltG+s+NNd+yvesae++ + +r+ T+ynak++ FUN_001041-T1 283 ytklgdlhprvqERVKKVDPAEYSNMANPNTFSSIAKISFKGKQRNDPSEAERLGNMSIGTKELTGYSENNDQYVESAETNATLRRFETHYNAKHY 378 ***********9999********************************************************************************* PP PPP1R32 353 enipkGldregwtrggiqpqkpdGyaksnkvtelekspntteslrklhPyvartiksrdpfyrdht 418 +++p+G dr+g+t+g++ q p+G++k ++v++l+++++tt++lr +Pyvar+ik+rdpfy+dht FUN_001041-T1 379 DMNPRGDDRKGRTDGNVFTQLPNGFTKGTSVHTLGPDIDTTAELRWQKPYVARSIKARDPFYDDHT 444 ****************************************************************97 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 5.4e-05 0.69 10 53 .. 256 299 .. 251 316 .. 0.84 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 5.4e-05 CODH_A_N 10 kygkdkkvefPnTaYyLPviyaltGekvktLgdleevLnrarsl 53 ++g++++ +f + + Pv y+ +G++ ++Lgdl++ +++ ++ FUN_001041-T1 256 SHGSERNTGFTHGTKARPVFYSKLGQEYTKLGDLHPRVQERVKK 299 68899999999999999*****************9988654444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (457 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 363 (0.0142102); expected 510.9 (0.02) Passed bias filter: 326 (0.0127618); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4508.69 // Query: FUN_001041-T2 [L=409] Description: FUN_001041 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-133 444.0 9.8 9.7e-133 443.8 9.8 1.0 1 PPP1R32 Protein phosphatase 1 regulatory subunit 32 ------ inclusion threshold ------ 0.23 12.0 0.0 0.59 10.7 0.0 1.6 1 CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-termi Domain annotation for each model (and alignments): >> PPP1R32 Protein phosphatase 1 regulatory subunit 32 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 443.8 9.8 7.6e-137 9.7e-133 1 350 [. 34 409 .] 34 409 .] 0.99 Alignments for each domain: == domain 1 score: 443.8 bits; conditional E-value: 7.6e-137 PPP1R32 1 mgkLplGvvspyvkaSsgadtdplkFYatsYstaYgreeFkprtgkhvGtGYksNfrpavsyqasLdkldnpamGellrDnyesvtkksyrplevp 96 mg+Lp+G+ ++++++S+gad ++kFY+t+Yst Yg+e+F+pr+g+h+GtGY+sNfrp v+y+++Ld+ldnpa G+ll+Dny+s+tkk++ p++++ FUN_001041-T2 34 MGRLPYGPGNAHILQSKGADVGVMKFYCTEYSTGYGQEGFNPRIGHHSGTGYQSNFRPGVYYSRRLDELDNPALGKLLTDNYASITKKHFLPSKGS 129 9*********************************************************************************************** PP PPP1R32 97 dgkeplprsvhqte.sgfvrekpktlptskevkkvhfdtqdagpkaipglepkerplLhklqkkdslevenaryGprymssEynskykgeepsqrd 191 g +p++r +++t+ sgfv+++p t+p+s++v+ vh+dt+ +g +++p +r+lL++l++kd++++en +Gp yms+E + ++ g +p+qr+ FUN_001041-T2 130 SGIDPFSRGLYMTAaSGFVKDIPVTVPRSRQVRDVHIDTRAKG-----TVYPYHRSLLYTLKHKDPISRENGFHGPSYMSTESQINFPG-TPKQRM 219 *************99****************************.....*****************************************.****** PP PPP1R32 192 llqkktiGakEesGFteesnkePitfqpks...qalpgdlvlrP.GvsvtksdylpvetakGdeflpvlakgseretGfsr............... 268 +++kkt+G+kE sGFt+++n+ePitf+p++ ++++++ ++rP G+s++k d+lpve+ +G+e lp l++gser+tGf++ FUN_001041-T2 220 DTSKKTMGYKEGSGFTHAHNDEPITFNPMEayeGIRDPRWTHRPtGFSIMKKDFLPVEYIHGNEKLPILSHGSERNTGFTHgtkarpvfysklgqe 315 *****************************99999************************************************************** PP PPP1R32 269 ............ekekkrdpletrvmtskseksslshlqfqgkqrmdqsnsellgrekvGnkEltGfslNNdsyvesaedpdraerylTtynak 350 e++kk dp e+++m+++++ ss+++++f+gkqr+d s++e+lg+ ++G kEltG+s+NNd+yvesae++ + +r+ T+ynak FUN_001041-T2 316 ytklgdlhprvqERVKKVDPAEYSNMANPNTFSSIAKISFKGKQRNDPSEAERLGNMSIGTKELTGYSENNDQYVESAETNATLRRFETHYNAK 409 ***********9999*****************************************************************************97 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 4.6e-05 0.59 10 53 .. 289 332 .. 284 349 .. 0.84 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 4.6e-05 CODH_A_N 10 kygkdkkvefPnTaYyLPviyaltGekvktLgdleevLnrarsl 53 ++g++++ +f + + Pv y+ +G++ ++Lgdl++ +++ ++ FUN_001041-T2 289 SHGSERNTGFTHGTKARPVFYSKLGQEYTKLGDLHPRVQERVKK 332 68899999999999999*****************9988654444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (409 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 420 (0.0164416); expected 510.9 (0.02) Passed bias filter: 372 (0.0145625); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4011.90 // Query: FUN_001042-T1 [L=377] Description: FUN_001042 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0026 18.0 7.5 0.0048 17.2 7.5 1.4 1 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) Domain annotation for each model (and alignments): >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 7.5 1.9e-07 0.0048 3 45 .. 295 345 .. 293 347 .. 0.83 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.9e-07 zf-C3HC4_3 3 eeCviClerern..vvllp.CgHlclCeeCaeklr.....kkkkCpiCrqk 45 +C+iC+ ++ + v+ ++ C+ l CeeC +++ +kkCp C+++ FUN_001042-T1 295 FMCKICHATPMTppVIATKcCNTLLGCEECVNTWFdgadgLSKKCPHCNEP 345 58******988754444443789999************999*******986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (377 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 941 (0.036837); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3795.62 // Query: FUN_001043-T1 [L=403] Description: FUN_001043 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-15 55.7 0.2 1.3e-14 54.9 0.2 1.3 1 rva_4 Integrase core domain ------ inclusion threshold ------ 0.26 12.1 0.1 1.7 9.4 0.0 2.2 2 HTH_21 HTH-like domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.9 0.2 9.8e-19 1.3e-14 11 168 .. 135 297 .. 126 305 .. 0.85 Alignments for each domain: == domain 1 score: 54.9 bits; conditional E-value: 9.8e-19 rva_4 11 WhidgnmklirWrlvvhGaidgysrlivyleastnnrastvlkq.flkavkkyglPsrvrsdkggenvk...vallmnllrG.lerssvitGrsvh 101 h+d n kl+ ++l+ a dgys iv + + ++ + ++ + +av ++g+ ++r d+g+e+ v + + +r ++r +i+ s + FUN_001043-T1 135 LHMDQNEKLAMYGLTEVSACDGYSGKIVAFATMPVKNNVLIYEHiYRTAVIQHGIWDQLRVDHGTEFYLslyVQEKLAPYRTnTRRVPFIQTTSKQ 230 6***********************8888776665555555555427899*****************96422266556555551566789******* PP rva_4 102 nqrierlWrdvfkkvvsvfyslftaledseildidndihllalhivylpriqkeleefknawnnhkl 168 n er W + +++v ++ + a+ +++++++d+d++++++ + +++ + +++ ++wnnh++ FUN_001043-T1 231 NHPAERKWVEFNTRVNYPIKRALNAMVNEDLINMDDDMNKFCVSWFTSRTADIGIRQVISSWNNHPI 297 *****************************************************************97 PP >> HTH_21 HTH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.1 0.18 2.3e+03 39 56 .. 38 55 .. 33 57 .. 0.81 2 ? 9.4 0.0 0.00013 1.7 3 45 .. 59 100 .. 58 103 .. 0.92 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.18 HTH_21 39 nrkrVaRLMrelgLrakr 56 + + V+R + ++g+ a+ FUN_001043-T1 38 SLRSVRRFCLKNGIHAQN 55 66789********98875 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00013 HTH_21 3 ddellelIkeifeesrgtYGyRritaeLrreggirvnrkrVaR 45 +del ++ ke+ ++ +t+G ++++ ++ gi+++ krV R FUN_001043-T1 59 NDELEQCTKEVVARVGPTWGRKMVKGYMASC-GITAGDKRVGR 100 56788999***********************.8********99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (403 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 656 (0.0256802); expected 510.9 (0.02) Passed bias filter: 599 (0.0234488); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3942.00 // Query: FUN_001044-T1 [L=221] Description: FUN_001044 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.052 14.2 12.8 1.2 9.9 2.0 2.4 2 C_tripleX Cysteine rich repeat 0.11 13.2 0.0 0.2 12.4 0.0 1.3 1 TscA TscA antitoxin 0.15 12.5 0.8 0.22 12.0 0.1 1.6 2 YgjP-like YgjP-like, metallopeptidase domain Domain annotation for each model (and alignments): >> C_tripleX Cysteine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 3.4 0.00021 1.8 2 15 .. 120 133 .. 119 134 .. 0.94 2 ? 9.9 2.0 0.00015 1.2 2 15 .. 197 210 .. 196 212 .. 0.91 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00021 C_tripleX 2 qCqPqCqqqCqgsC 15 +C P C q C ++C FUN_001044-T1 120 SCKPLCKQRCLPTC 133 7************* PP == domain 2 score: 9.9 bits; conditional E-value: 0.00015 C_tripleX 2 qCqPqCqqqCqgsC 15 C+ C ++C +sC FUN_001044-T1 197 RCDANCKKACLPSC 210 6************* PP >> TscA TscA antitoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 2.3e-05 0.2 21 65 .. 37 80 .. 27 82 .. 0.91 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.3e-05 TscA 21 enkletYeHttvtkdGevevsevsREkHLEsimkWavqeleknFk 65 +n +++ H ++dG++ + + + Ek +E+ a+++le++Fk FUN_001044-T1 37 ANSIQAKLHD-GKVDGKIPINKTEMEKNIEEKTSQAIKKLENQFK 80 6777888898.99*******************************8 PP >> YgjP-like YgjP-like, metallopeptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 2.6e-05 0.22 64 147 .. 36 122 .. 12 127 .. 0.74 2 ? -2.1 0.1 0.53 4.5e+03 88 95 .. 166 173 .. 144 206 .. 0.45 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.6e-05 YgjP-like 64 lGkeyrlkveegkeasvkakreeeelivkkeeeeeklrkaleewlrkeakeeleer..lerlakklgvkvssvsikkmktr..WGscs 147 l ++++ k+++gk + k+ ++ e+ ee++++ k+le+ ++ ++ +e + + ++l+++++s+++++ +++ WGsc+ FUN_001044-T1 36 LANSIQAKLHDGK-VDGKIPINKTEMEKNIEEKTSQAIKKLENQFKATFMAYTSENktAGETHPNLERTFRSLNVREKRSKgsWGSCK 122 5666777777777.333333444444555556666677778888888877777665558899999***********9988778****6 PP == domain 2 score: -2.1 bits; conditional E-value: 0.53 YgjP-like 88 elivkkee 95 + i k++ FUN_001044-T1 166 SDIKKPSV 173 22222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1687 (0.0660403); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2203.29 // Query: FUN_001045-T1 [L=127] Description: FUN_001045 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.088 13.3 0.0 3.8 8.1 0.0 2.2 2 TerS_N Phage G20C small terminase, N-terminal domain Domain annotation for each model (and alignments): >> TerS_N Phage G20C small terminase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.00015 3.8 2 22 .. 30 53 .. 29 59 .. 0.83 2 ? 3.1 0.0 0.0052 1.3e+02 12 28 .. 77 93 .. 72 102 .. 0.85 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.00015 TerS_N 2 vsfRDRvLkLYL....LGfDPseia 22 +sfRD L LYL LGf P ia FUN_001045-T1 30 ISFRDVDLALYLhdaaLGFGPK-IA 53 7**********98888899984.55 PP == domain 2 score: 3.1 bits; conditional E-value: 0.0052 TerS_N 12 YLLGfDPseiaqtLsLD 28 Y++ DPs i q sL FUN_001045-T1 77 YVIDPDPSFICQVNSLS 93 78888*******99985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (127 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 408 (0.0159718); expected 510.9 (0.02) Passed bias filter: 346 (0.0135447); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 1232.26 // Query: FUN_001046-T1 [L=388] Description: FUN_001046 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (388 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 775 (0.0303386); expected 510.9 (0.02) Passed bias filter: 241 (0.00943433); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 3754.87 // Query: FUN_001047-T1 [L=561] Description: FUN_001047 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-17 63.7 20.1 4e-17 63.0 20.1 1.3 1 7tm_1 7 transmembrane receptor (rhodopsin family) 6.7e-07 29.9 0.9 2e-06 28.3 0.4 2.1 1 LRR_4 Leucine Rich repeats (2 copies) 1.1e-06 28.8 0.6 2.2e-06 27.8 0.6 1.6 1 LRR_8 Leucine rich repeat 0.01 16.3 2.9 11 7.2 0.0 4.0 3 LRR_1 Leucine Rich Repeat ------ inclusion threshold ------ 0.016 15.7 0.6 3.5 8.4 0.1 2.8 2 LRR_6 Leucine Rich repeat 0.069 13.2 10.1 0.13 12.3 5.5 2.6 2 DUF2512 Protein of unknown function (DUF2512) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.0 20.1 9.4e-21 4e-17 2 259 .. 240 502 .. 239 502 .. 0.76 Alignments for each domain: == domain 1 score: 63.0 bits; conditional E-value: 9.4e-21 xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtpt.nifllnLavaDllvll........lvlpfalvyallegdwvf.gevlCklvtaldvvnltasillltaisiDRYlaI 87 N++++++++ ++lr++t +++ n+a++Dll+++ ++ f ++++ + f ++ lC + t++++ + ++ + ++++i+ Yl+I FUN_001047-T1 240 NFIILVTVFSARSLRNSTsMLLISNMALCDLLMGIysviigdlNIFNFISNAYATGAKLSFeKQELCGFSTVIFTSAQCVAAATSLLLTIEKYLSI 335 999*************66378899***********8876665322222222222334444456778****************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF 7tm_1 88 vkplkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpl.lvilvcyvrilrtlrk 182 v+ + +r+ +k++a+ +++ Wvl+ll s+ p+++ + + +C++ + + +++l++ ++l+ l l+ + +yv i+ +rk FUN_001047-T1 336 VYCMDPNRRLSKKVAFSSVILLWVLSLLYSISPIFGVFGLSM---SVPLMCSFPIAS-------GANTFLIFPSVLIALyLINIPLYVAIFISVRK 421 ***********************************9888777...7899**999988.......6666666666666550455669********** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxx RF 7tm_1 183 sakkekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsl........lkeceseklvetallitll....layvnsclNPii 259 s + k++ + k+ lvvv f+l+ +P+ ++++l + l + +k+++ +l++ + + +nsc+NPi+ FUN_001047-T1 422 SGANLGIKRETV-----ILKKIALVVVTNFLLLLTPFILIITLVPTknihksleL---DGSKNTQMLLIFGFWfpiaCLGFNSCINPIL 502 ***999844433.....455688888889999*****999999998999886552...33333333333333300004458******96 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.4 4.7e-10 2e-06 2 39 .. 68 106 .. 68 116 .. 0.86 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 4.7e-10 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitdl 39 +L+tL+L++N+i+ i ++ LpnL++LdL + n++++ FUN_001047-T1 68 QLTTLSLAYNHISVIKDcdFGTLPNLTSLDL-RFNPLKTW 106 69***************55557*********.66698876 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.8 0.6 5.2e-10 2.2e-06 2 53 .. 68 119 .. 49 125 .. 0.79 Alignments for each domain: == domain 1 score: 27.8 bits; conditional E-value: 5.2e-10 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrs 53 +L++L+L +N++++++d F l+nL++LdL+ N l+t ++ Lp+L FUN_001047-T1 68 QLTTLSLAYNHISVIKDCDFGTLPNLTSLDLRFNPLKTWTGDVKTKLPNLLN 119 5888888888888888888888888888888888888888888888887754 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.1 1.4 6.1e+03 6 20 .. 49 62 .. 49 65 .. 0.72 2 ! 7.2 0.0 0.0026 11 1 22 [. 68 89 .. 68 90 .. 0.85 3 ! 6.7 0.2 0.0038 16 1 13 [. 92 105 .. 92 119 .. 0.79 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 1.4 LRR_1 6 dLsnNnlsgllpesl 20 +Ls N l+ + p + FUN_001047-T1 49 NLSKNDLE-IVPTPF 62 79*****6.666544 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0026 LRR_1 1 nLeeLdLsnNnlsgllpeslgn 22 +L++L+L++N++s + ++g FUN_001047-T1 68 QLTTLSLAYNHISVIKDCDFGT 89 59**********9888887776 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0038 LRR_1 1 nLeeLdLsnNnl.s 13 nL++LdL+ N+l + FUN_001047-T1 92 NLTSLDLRFNPLkT 105 8**********951 PP >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.012 53 5 16 .. 69 80 .. 69 81 .. 0.94 2 ? 8.4 0.1 0.00081 3.5 3 15 .. 91 103 .. 89 105 .. 0.87 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.012 LRR_6 5 LteLdLsgNdIg 16 Lt+L L++N+I+ FUN_001047-T1 69 LTTLSLAYNHIS 80 9*********96 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00081 LRR_6 3 ttLteLdLsgNdI 15 ++Lt+LdL++N + FUN_001047-T1 91 PNLTSLDLRFNPL 103 89*********76 PP >> DUF2512 Protein of unknown function (DUF2512) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 5.5 3e-05 0.13 5 85 .. 235 317 .. 233 334 .. 0.73 2 ? 2.6 0.1 0.031 1.3e+02 7 29 .. 345 367 .. 339 385 .. 0.80 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 3e-05 DUF2512 5 kalliKfiatlivlli..vlgiflgvsfseillisliltlvsYligDlliLprlgnviAtiaDlglafvvvwllsivlldesv 85 +a+++ fi++++v+++ + + +s++ l l++++ s +igDl i++ ++n+ At a l + + +s+v++ ++ FUN_001047-T1 235 VAIILNFIILVTVFSArsLRNSTSMLLISNMALCDLLMGIYSVIIGDLNIFNFISNAYATGAKLSFEKQELCGFSTVIFTSAQ 317 57788888888888752134455667789999999*************************99988876666666555554444 PP == domain 2 score: 2.6 bits; conditional E-value: 0.031 DUF2512 7 lliKfiatlivllivlgiflgvs 29 l K+++++++ll vl++ + +s FUN_001047-T1 345 LSKKVAFSSVILLWVLSLLYSIS 367 7789**************99886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (561 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 747 (0.0292425); expected 510.9 (0.02) Passed bias filter: 363 (0.0142102); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 5540.34 // Query: FUN_001048-T1 [L=411] Description: FUN_001048 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (411 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 763 (0.0298689); expected 510.9 (0.02) Passed bias filter: 197 (0.00771188); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 4074.45 // Query: FUN_001049-T1 [L=585] Description: FUN_001049 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-20 73.9 0.6 3.4e-20 72.9 0.6 1.5 1 Saposin Saposin-like domain 1.2e-14 55.4 0.0 2.1e-14 54.7 0.0 1.4 1 Lipase_GDSL GDSL-like Lipase/Acylhydrolase 0.0001 23.3 0.0 0.00026 22.1 0.0 1.7 2 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family 0.0049 17.6 2.8 0.013 16.2 2.8 1.8 1 Cu-binding_MopE Putative metal-binding motif 0.0053 17.4 2.7 0.0092 16.6 0.2 2.5 2 SapB_2 Saposin-like type B, region 2 Domain annotation for each model (and alignments): >> Saposin Saposin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.9 0.6 6.6e-24 3.4e-20 2 103 .. 43 142 .. 42 160 .. 0.89 Alignments for each domain: == domain 1 score: 72.9 bits; conditional E-value: 6.6e-24 Saposin 2 cvgcvvvvsvieqlaqvhnstvkaalerlcsylpeklflkttcyllvevfGsdiikllekdmnadvvchtlefckqeagqplchlyplpkeawklt 97 c+ c vv++ eql+ +hn t ++ rlc lp+ l + +c+ l + + + +i ll +++ adv+c ++ +c qe+gqp+ch +p+ k+ FUN_001049-T1 43 CLVCTAVVAITEQLSIIHNETFVKSYSRLCDVLPK-L-YREACISLGKFYIPLVIDLLTEEVSADVICNAIFLCYQEKGQPYCHAFPPKKHFAAKV 136 999*******************************6.4.4899*********************************************998765544 PP Saposin 98 lekarr 103 l+ ++ FUN_001049-T1 137 LKYRKK 142 444444 PP >> Lipase_GDSL GDSL-like Lipase/Acylhydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.7 0.0 4.1e-18 2.1e-14 1 206 [. 263 551 .. 263 553 .. 0.80 Alignments for each domain: == domain 1 score: 54.7 bits; conditional E-value: 4.1e-18 Lipase_GDSL 1 ivafGDS...........ltdggg......dgpg...grfswgdl.ladflarklgvs..............g.sgynk..ganfaisGatiedlg 58 ++++GDS lt++++ + ++ ++f w++l l++ + rk + + +++n+ + n+a +Ga + FUN_001049-T1 263 VIVIGDSvaghfhippewLTAHFFsekifkNAAFiveNEFDWPQLsLYSGYLRKSRWPmerghsdsiylklwErNHCNHrdYQNLAKNGADS---F 355 57899*9555555555555555559999987777888889******9999999999999*************88**************9987...5 PP Lipase_GDSL 59 iqleqllrlksdvkdqakpdlvtieiGaNDllnal......ssparskkrleelldelranlpelgarkflvhglgplgctp.............. 134 + ++ll + ++ q++p+lv+ ++ +ND++++ ++p++ ++++ ++l +l ++lp+ ++++++ gl + + FUN_001049-T1 356 EANSRLLPSMARSREQDQPALVFYSLIGNDVCHHVhnlsamTTPQEMRQNVLKTLHTLDKRLPN--GSHVILIGLVDGRVLFnslhnrihpigklr 449 58888888888888**************************************************..555555555555222234455544444443 PP Lipase_GDSL 135 .....ek..................ceelynalaeeynerlnelvnslaaaaedanvvlvdi....ygfedptkpccgigse......fwDglHps 197 e+ +e ++++++e e+l+++++++a++ +++ +d+ ++ +k + ++g+ Dg+Hp+ FUN_001049-T1 450 gdvtyEQlydflnclhvspcygwlnSNESIRNATSERAEQLTAVLQAVAEK---SKFENFDLffleCPIKEVIKEWVRKGGKvyeliePVDGFHPT 542 44445115555666777888999999*************************...55555555554547788888888888889999*999****** PP Lipase_GDSL 198 ekgykavae 206 + +++a+ FUN_001049-T1 543 METEALMAN 551 *******98 PP >> Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 3.1 1.6e+04 143 172 .. 210 246 .. 181 247 .. 0.53 2 ! 22.1 0.0 5e-08 0.00026 26 174 .. 333 544 .. 308 548 .. 0.79 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 3.1 Lipase_GDSL_2 143 gvpfvdladaladddgrlpdlladdg.......lHPn 172 g + d++++ +++++++ + d +HPn FUN_001049-T1 210 GRDCDDINSLHHPGAKPRNGDVIYDSncngisgIHPN 246 4444455444444444444444444455556777777 PP == domain 2 score: 22.1 bits; conditional E-value: 5e-08 Lipase_GDSL_2 26 llaerl.gadvvnnlgisGatt..allrllerld.allrlkpdlvvillGtND.......lgrgvpparaaannlealvrrlraa.apgarvl... 106 l+ +++ +++ + nl+ +Ga + a+ rll+ ++ + +p lv+ +l +ND l + ++p++ ++n + + + +l ++ g +v+ FUN_001049-T1 333 LWERNHcNHRDYQNLAKNGADSfeANSRLLPSMArSREQDQPALVFYSLIGNDvchhvhnLSAMTTPQEMRQN-VLKTLHTLDKRlPNGSHVIlig 427 55555564444555********89788888888889999999***********77766666666666666666.6666666666644444555678 PP Lipase_GDSL_2 107 ......................................glgplpvgpppppdarrlnarlaalneairevaaeegvpfvdl...........adal 153 + ++++ +++ ++++++r+++l +++++va++ +++ +dl +++ FUN_001049-T1 428 lvdgrvlfnslhnrihpigklrgdvtyeqlydflnclhVSPCYGWLNSNESIRNATSERAEQLTAVLQAVAEKSKFENFDLfflecpikeviKEWV 523 88888888888888888888888888888889999888999****************************************988888888888888 PP Lipase_GDSL_2 154 adddgrlpdlladdglHPnaa 174 +++++ ++ dg+HP+ + FUN_001049-T1 524 RKGGKVYELIEPVDGFHPTME 544 888888888888888***976 PP >> Cu-binding_MopE Putative metal-binding motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 2.8 2.6e-06 0.013 1 27 [. 212 240 .. 212 241 .. 0.96 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.6e-06 Cu-binding_MopE 1 DCDDndpsihPgaaEiC.Dgi.DnnCdGr 27 DCDD ++ hPga + D i D+nC+G+ FUN_001049-T1 212 DCDDINSLHHPGAKPRNgDVIyDSNCNGI 240 9*******************99******6 PP >> SapB_2 Saposin-like type B, region 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.2 1.8e-06 0.0092 10 31 .. 90 111 .. 88 114 .. 0.91 2 ? -0.6 0.2 0.43 2.2e+03 25 32 .. 384 391 .. 383 391 .. 0.88 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 1.8e-06 SapB_2 10 YgplIidlLengldPkdvCtal 31 Y+pl+idlL ++++++++C a+ FUN_001049-T1 90 YIPLVIDLLTEEVSADVICNAI 111 *******************998 PP == domain 2 score: -0.6 bits; conditional E-value: 0.43 SapB_2 25 kdvCtalg 32 +dvC++++ FUN_001049-T1 384 NDVCHHVH 391 69****98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (585 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 625 (0.0244666); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5611.28 // Query: FUN_001050-T1 [L=69] Description: FUN_001050 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (69 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 593 (0.0232139); expected 510.9 (0.02) Passed bias filter: 311 (0.0121746); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.41s 00:00:00.62 Elapsed: 00:00:00.38 # Mc/sec: 722.17 // Query: FUN_001051-T1 [L=577] Description: FUN_001051 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-55 187.1 1.3 7.1e-55 186.5 1.3 1.3 1 RabGAP-TBC Rab-GTPase-TBC domain 2.3e-30 106.3 4.3 4.3e-30 105.5 4.3 1.4 1 RabGap-TBC_2 RabGAP TBC domain Domain annotation for each model (and alignments): >> RabGAP-TBC Rab-GTPase-TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 186.5 1.3 5.5e-59 7.1e-55 2 213 .. 103 307 .. 102 310 .. 0.95 Alignments for each domain: == domain 1 score: 186.5 bits; conditional E-value: 5.5e-59 RabGAP-TBC 2 elRgkvWklllgaekevkklkkeekkqeksskeeselekkeeseeeeqIekDvprtfp.hs.fsfkngegqesLrriLkaysiynpdvgYcqGmnf 95 +lRg++Wk llg++k + +e++++ +++s++++qI++Dv+rt++ h f++++g q+ L+++L ays+yn +vgYcqGm+ FUN_001051-T1 103 ALRGEAWKKLLGIDK---------VPNGSAAYESMKWLARSQSPDIRQIDLDVNRTYRdHImFRDRYGIKQQALFHVLAAYSMYNVEVGYCQGMSG 189 79***********64.........567778889999999999999*************7779********************************** PP RabGAP-TBC 96 ivapllllyldeeeaFwcfvsLl..ekyklrdlytsdfpglkkalkvfeellkkklpklykhlkelgidlelfalkWfltlflrefplslvlriwD 189 i+a+ll +yl+ee+aFw++++Ll +k+ ++ ++ ++fp+l ++++ +++lkk l++l+k l+++g++++l++lkWf+ +fl+ p++l+lr+wD FUN_001051-T1 190 IAALLL-MYLNEEDAFWALSALLtdKKHAMHGFFVPGFPKLLRFQEHHDKILKKLLSRLFKNLEKEGCHSSLYTLKWFMQCFLDRTPFTLTLRLWD 284 ******.*****************999********************************************************************* PP RabGAP-TBC 190 vlllegekvvllrvalailkllke 213 +++leg++ l +a i+k++++ FUN_001051-T1 285 IFMLEGDRL-LTAMAYNIMKMHRK 307 9999***77.8889999*****97 PP >> RabGap-TBC_2 RabGAP TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.5 4.3 3.4e-34 4.3e-30 1 168 [. 164 333 .. 164 350 .. 0.90 Alignments for each domain: == domain 1 score: 105.5 bits; conditional E-value: 3.4e-34 RabGap-TBC_2 1 qeslfkvlkaysLyDtevgYaqgllfiaaplllympeeeaFsllvkLl..kkydlrelfipdmpglelrLyqferlledllpalaihLqrqgvkss 94 q++lf+vl ays+y evgY+qg++ iaa ll+y++ee+aF +l Ll kk + ++f+p p+l +++l++ll l+ L+++g +ss FUN_001051-T1 164 QQALFHVLAAYSMYNVEVGYCQGMSGIAALLLMYLNEEDAFWALSALLtdKKHAMHGFFVPGFPKLLRFQEHHDKILKKLLSRLFKNLEKEGCHSS 259 578*********************************************334568***********98777799*********************** PP RabGap-TBC_2 95 myasqwfltlFaykfpldlvlRifDlviaeGleailrlaiallkkneekllkllkldqllkfLkedlfdv.Yiqe 168 +y +wf+ +F ++ p +l lR++D+ + eG + +a +++k ++ ++k + l+++++fL+e++ + Y ++ FUN_001051-T1 260 LYTLKWFMQCFLDRTPFTLTLRLWDIFMLEGDRLLTAMAYNIMKMHRKIFVK-MGLEEVVQFLQERMHSYpYDDD 333 ********************************************99999999.*************976424344 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (577 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 741 (0.0290076); expected 510.9 (0.02) Passed bias filter: 549 (0.0214915); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5477.64 // Query: FUN_001052-T1 [L=244] Description: FUN_001052 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-23 81.9 6.0 3.7e-23 81.6 4.4 2.1 2 Homeodomain Homeodomain 0.00016 21.9 0.3 0.00045 20.5 0.2 1.8 2 Homeobox_KN Homeobox KN domain 0.006 16.7 0.0 0.014 15.5 0.0 1.6 1 CENP-B_N CENP-B N-terminal DNA-binding domain Domain annotation for each model (and alignments): >> Homeodomain Homeodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 1.5 1.3e+04 10 25 .. 23 38 .. 20 39 .. 0.73 2 ! 81.6 4.4 4.4e-27 3.7e-23 1 57 [] 151 207 .. 151 207 .. 0.99 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 1.5 Homeodomain 10 eqleeLekeFeenryp 25 e ++L +F +++ p FUN_001052-T1 23 ENRKRLGMFFSQDPMP 38 5667888888888766 PP == domain 2 score: 81.6 bits; conditional E-value: 4.4e-27 Homeodomain 1 rrkRttftkeqleeLekeFeenrypsaeereeLAkklgLserqVkvWFqNrRakekk 57 r++Rt ft+ ql++Lek F ++y++++ r++LA+ lgL+e+qVk+WFqNrR+k+kk FUN_001052-T1 151 RKSRTVFTDLQLRILEKTFSDQKYLDTSSRAKLAQTLGLNETQVKTWFQNRRMKWKK 207 89******************************************************8 PP >> Homeobox_KN Homeobox KN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 1.1 9.4e+03 11 25 .. 86 100 .. 86 102 .. 0.76 2 ! 20.5 0.2 5.3e-08 0.00045 15 39 .. 179 203 .. 174 204 .. 0.91 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 1.1 Homeobox_KN 11 PseeeKeeLaketgl 25 P +e ++a ++g FUN_001052-T1 86 PHSHEQTQIASASGS 100 677888899988876 PP == domain 2 score: 20.5 bits; conditional E-value: 5.3e-08 Homeobox_KN 15 eKeeLaketglsrkqisnWFiNaRr 39 +++La+ gl+++q+++WF N R+ FUN_001052-T1 179 SRAKLAQTLGLNETQVKTWFQNRRM 203 6799*******************96 PP >> CENP-B_N CENP-B N-terminal DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 1.7e-06 0.014 17 47 .. 172 202 .. 161 203 .. 0.90 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.7e-06 CENP-B_N 17 qrleegeSkaslarrfgvpesTlrqilknKk 47 q++ ++ S+a la+ +g+ e++++++ +n + FUN_001052-T1 172 QKYLDTSSRAKLAQTLGLNETQVKTWFQNRR 202 6677999*******************99975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (244 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 976 (0.0382071); expected 510.9 (0.02) Passed bias filter: 466 (0.0182423); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2428.99 // Query: FUN_001053-T1 [L=895] Description: FUN_001053 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-66 219.4 0.5 2e-17 64.1 0.0 5.3 5 SNase Staphylococcal nuclease homologue 6.4e-29 101.0 0.0 1.4e-28 99.9 0.0 1.5 1 TUDOR Tudor domain ------ inclusion threshold ------ 0.017 16.1 0.1 0.086 13.8 0.0 2.1 2 MtrB Tetrahydromethanopterin S-methyltransferase subuni 0.037 14.6 0.1 4.1 8.1 0.0 2.7 2 DUF8065 Family of unknown function (DUF8065) 0.037 14.3 2.5 34 4.8 0.1 4.8 5 DUF6897 Domain of unknown function (DUF6897) 4.9 7.5 9.6 6 7.2 0.4 3.4 3 Remorin_C Remorin, C-terminal region Domain annotation for each model (and alignments): >> SNase Staphylococcal nuclease homologue # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.2 0.0 1.1e-12 4.5e-09 3 106 .. 38 154 .. 36 155 .. 0.92 2 ! 43.3 0.0 1.4e-14 5.8e-11 2 107 .] 209 315 .. 208 315 .. 0.90 3 ! 38.9 0.0 3.2e-13 1.4e-09 17 106 .. 384 484 .. 355 485 .. 0.85 4 ! 64.1 0.0 4.7e-21 2e-17 4 107 .] 544 652 .. 541 652 .. 0.92 5 ! 27.8 2.0 9.2e-10 3.9e-06 25 106 .. 798 879 .. 794 880 .. 0.91 Alignments for each domain: == domain 1 score: 37.2 bits; conditional E-value: 1.1e-12 SNase 3 rLvgidaPetakpkk.........tvqpfgkeAkeflkklvlqkkvvvleldk.Dkygrllayvyln...rkknineeLvkeGlArvyevyeknee 85 L++++aP+ a++ + +pf+ eA+efl+k++++k+v +++ k gr + ++l+ + +ni e +v eGl v + k ++ FUN_001053-T1 38 CLSNVNAPKLARRSNpnvegsvetRDEPFAWEAREFLRKKLIGKEVLFTVEYKvPGTGREYGCIFLQkgqELENITESIVTEGLVEVRRGGIKPSD 133 699********999999******999********************9887766699***********998899*************9996666789 PP SNase 86 kkkellkaeeeAkkkkkglWs 106 ++ +l +ee Ak++ +g Ws FUN_001053-T1 134 DQVKLIDLEELAKSDGRGKWS 154 99******************8 PP == domain 2 score: 43.3 bits; conditional E-value: 1.4e-14 SNase 2 vrLvgidaPetakpkk..tvqpfgkeAkeflkklvlqkkvvvleldkDkygrllayvylnrkknineeLvkeGlArvye.vyekneekkkellkae 94 v + g+ +P ++ + +pf +eAk f+++++lq++v+++ ++ ++++++++++ + ni+e L++eG+Ar + + ++ +++l++ae FUN_001053-T1 209 VMFTGVKCPMIRREGDkeIPEPFSDEAKFFTESRLLQREVKIILEGV-SNQNYIGTIIHP-AGNIAELLLREGFARCVDwSMAVLSKGHDKLRAAE 302 788999999988777655789***************99999988887.6889********.***************99966666999********* PP SNase 95 eeAkkkkkglWsd 107 + A++k++ lW++ FUN_001053-T1 303 RFAREKRLRLWKN 315 ***********85 PP == domain 3 score: 38.9 bits; conditional E-value: 3.2e-13 SNase 17 k....tvqpfgkeAkeflkklvlqkkvvvleldk.....DkygrllayvylnrkknineeLvkeGlArvye.vyek...neekkkellkaeeeAkk 99 k + p+ eA+efl+k++++kkv v+++ + +r+ a+v + + n++e+L+ +G+A+v + + ++ ++ ++ell+ae A k FUN_001053-T1 384 KprplYDIPYMLEAREFLRKKLIGKKVNVKIDYVkppsdGFPERTCATVTIG-GVNVAEALISKGFATVLRhR-QDddqRSSCYDELLSAETRAAK 477 134557789*******************999888899966789*********.****************9953.3324678889************ PP SNase 100 kkkglWs 106 + kgl s FUN_001053-T1 478 NAKGLHS 484 ****965 PP == domain 4 score: 64.1 bits; conditional E-value: 4.7e-21 SNase 4 LvgidaPetakpkk.......tvqpfgkeAkeflkklvlqkkvvvleldkDkygrllayvylnrkknineeLvkeGlArvyevyekneekkkellk 92 +gi +P+ + + + +pfg+eA +f+k+l++qk+v+v+++ +Dk g++++ ++++ ++n++ +Lv++Gl +v++ e +++ +++l FUN_001053-T1 544 VAGITCPRAGRIVTsqgviatQGEPFGDEALAFTKDLCMQKEVEVEVEAIDKAGNFIGWLFVE-NTNLSVALVEAGLSQVHFTAE-RSNFYHQLTV 637 67899999988877888999899****************************************.***************999666.5789****** PP SNase 93 aeeeAkkkkkglWsd 107 ae +Ak+ k+ lW++ FUN_001053-T1 638 AEGQAKSSKIKLWAN 652 *************85 PP == domain 5 score: 27.8 bits; conditional E-value: 9.2e-10 SNase 25 eAkeflkklvlqkkvvvleldkDkygrllayvylnrkknineeLvkeGlArvyevyek.neekkkellkaeeeAkkkkkglWs 106 +A + k+lv++++ +++++ k +++ ++ v n +++++++Lv +Gl +v +++ek ++ +e++ka++ A+k++++lW FUN_001053-T1 798 DALDAFKNLVINRQFMLNVEFKVSNQVYVTLVQEN-GEDVAKTLVSDGLVTVEKRKEKrLQKVMDEYNKAQDVARKARVNLWR 879 57788999999999999999999999999999999.***************999666658999*******************6 PP >> TUDOR Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 99.9 0.0 3.2e-32 1.4e-28 5 120 .. 670 785 .. 666 785 .. 0.91 Alignments for each domain: == domain 1 score: 99.9 bits; conditional E-value: 3.2e-32 TUDOR 5 etidvvvseiespstfyiqpkesskkleklteelqeyykskpk.eslkpkvgegcvavfsedgkwyRAkiteslddqkveVlfiDyGntetvplsd 99 ++ +vvv+e + + f++q++es +lekl+ +l+ +++p+ ++ +++++++ +a+ +d++wyRA++ e+ ++++v+V++iDyGn e++p s+ FUN_001053-T1 670 NFKKVVVTETQRSLSFWAQHVESGGQLEKLMADLHNELSTNPPlPGSYTARKGDLCAALFVDNNWYRARV-ENISSKQVHVFYIDYGNKEVLPQSK 764 6789****************************************66666666666666667*********.************************* PP TUDOR 100 lrelpeeleslppqaikcsLa 120 l++lp+++ s+ppqa+++ La FUN_001053-T1 765 LCPLPSSFHSFPPQAHEYHLA 785 ****************99885 PP >> MtrB Tetrahydromethanopterin S-methyltransferase subunit B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 2e-05 0.086 39 80 .. 694 735 .. 664 741 .. 0.86 2 ? -1.8 0.1 1.4 6.1e+03 7 33 .. 817 843 .. 814 866 .. 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 2e-05 MtrB 39 dkLekiaddlvnsLdpetellesypgRektlaiaGiltnlfy 80 +Lek+ dl n L+ + +l sy R + l a ++ n +y FUN_001053-T1 694 GQLEKLMADLHNELSTNPPLPGSYTARKGDLCAALFVDNNWY 735 68***************************************9 PP == domain 2 score: -1.8 bits; conditional E-value: 1.4 MtrB 7 elnlvldpetgvvaearedvvvlsldp 33 e+++ ++ + +v+e++edv + +++ FUN_001053-T1 817 EFKVSNQVYVTLVQENGEDVAKTLVSD 843 788888999999999999997765554 PP >> DUF8065 Family of unknown function (DUF8065) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.00095 4.1 24 61 .. 431 469 .. 426 476 .. 0.86 2 ? 3.4 0.1 0.027 1.2e+02 65 87 .. 832 854 .. 822 869 .. 0.82 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.00095 DUF8065 24 eirlGGinvsE.LaReGlkekLrevlsdeekialyeryk 61 + +GG+nv E L +G + +Lr+ +d+++ y+ FUN_001053-T1 431 TVTIGGVNVAEaLISKGFATVLRHRQDDDQRSSCYDELL 469 5789*****99799****************999998765 PP == domain 2 score: 3.4 bits; conditional E-value: 0.027 DUF8065 65 lsEdvarvllgdkldeieeerea 87 Edva+ l+ d l ++e+ +e+ FUN_001053-T1 832 NGEDVAKTLVSDGLVTVEKRKEK 854 579**************998875 PP >> DUF6897 Domain of unknown function (DUF6897) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.25 1.1e+03 2 14 .. 71 83 .. 70 88 .. 0.89 2 ? 3.3 0.0 0.024 1e+02 4 38 .. 238 274 .. 235 285 .. 0.83 3 ? 0.5 0.0 0.17 7.4e+02 22 42 .. 328 350 .. 312 356 .. 0.70 4 ? 4.8 0.1 0.0081 34 2 18 .. 398 414 .. 397 418 .. 0.89 5 ? -2.2 0.0 1.2 5.1e+03 4 19 .. 576 591 .. 575 595 .. 0.81 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.25 DUF6897 2 qsFivehylgkkv 14 ++F+ ++++gk+v FUN_001053-T1 71 REFLRKKLIGKEV 83 68*********99 PP == domain 2 score: 3.3 bits; conditional E-value: 0.024 DUF6897 4 FivehylgkkvdvycgG..pdvlrGkvvecaDgvltL 38 F + +l+++v++ ++G ++++ G++ a+++ L FUN_001053-T1 238 FTESRLLQREVKIILEGvsNQNYIGTIIHPAGNIAEL 274 4556799**********9999******9999888665 PP == domain 3 score: 0.5 bits; conditional E-value: 0.17 DUF6897 22 dvlrGkvvec.aDgvltLk.kdd 42 + + Gkv ec + + l++k +d+ FUN_001053-T1 328 KEFTGKVMECvNADALVIKnQDG 350 7899*****94456777773444 PP == domain 4 score: 4.8 bits; conditional E-value: 0.0081 DUF6897 2 qsFivehylgkkvdvyc 18 ++F+ ++++gkkv+v + FUN_001053-T1 398 REFLRKKLIGKKVNVKI 414 68************976 PP == domain 5 score: -2.2 bits; conditional E-value: 1.2 DUF6897 4 Fivehylgkkvdvycg 19 F ++ ++k+v+v ++ FUN_001053-T1 576 FTKDLCMQKEVEVEVE 591 7788899*****9875 PP >> Remorin_C Remorin, C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 0.25 1e+03 61 84 .. 293 316 .. 288 333 .. 0.76 2 ? 3.3 0.9 0.022 96 23 58 .. 641 676 .. 637 683 .. 0.87 3 ? 7.2 0.4 0.0014 6 50 79 .. 847 876 .. 837 879 .. 0.92 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.25 Remorin_C 61 klknklarihkkAeekRasaeakr 84 k ++kl+++++ A ekR ++ ++ FUN_001053-T1 293 KGHDKLRAAERFAREKRLRLWKNY 316 66789************8876665 PP == domain 2 score: 3.3 bits; conditional E-value: 0.022 Remorin_C 23 kkeeakIqaWenkkkakaeaelkkleeklEkkkaea 58 + + +kI+ W n + k e++++e+k + kk FUN_001053-T1 641 QAKSSKIKLWANYEEPKNIVEIEETERKCNFKKVVV 676 67899***********************99988655 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0014 Remorin_C 50 klEkkkaealeklknklarihkkAeekRas 79 +Ek+k + l+k++++ ++++ A ++R + FUN_001053-T1 847 TVEKRKEKRLQKVMDEYNKAQDVARKARVN 876 69************************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (895 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 768 (0.0300646); expected 510.9 (0.02) Passed bias filter: 618 (0.0241926); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 8544.03 // Query: FUN_001054-T1 [L=449] Description: FUN_001054 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-10 41.8 0.1 6.5e-10 39.1 0.1 2.2 1 PhoD PhoD-like phosphatase ------ inclusion threshold ------ 0.15 13.0 0.0 0.96 10.3 0.0 2.0 1 Metallophos Calcineurin-like phosphoesterase Domain annotation for each model (and alignments): >> PhoD PhoD-like phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 0.1 5.1e-14 6.5e-10 3 271 .. 49 277 .. 47 326 .. 0.77 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 5.1e-14 PhoD 3 vvsCq.nyeagyfnayrelaredldlvlhlGDyiYeygeeeykldgelvrnleppakeavtladYReryaqyktDpdlqal.haavpwivtwDDHE 96 + sC+ +++ ++++ ++++dl+++lGD +Y+++ + + ++ p l + ++++ k + ++q++ ++ + ++ +wDDH FUN_001054-T1 49 FGSCSySFPNKPQPLWEHISKQKPDLWVWLGDAVYADT------KIAPLTWTPSP------LVEMVGKFNALKYSLEYQKFlESGIHVLGVWDDHD 132 567852578888999**********************5......33333333444......77888999999999999996156688999*****6 PP PhoD 97 vaNnwadgaenhneetegdfearkaaAvqAyfEw..mPirqskpgdeeriyrsleyG...dladlfvLDtRqyrsdqalnaeaaeeevedpdrtll 187 n + +n + + +A y+++ P++ +++e y s+ +G + ++l++LDtR++ + + d +l FUN_001054-T1 133 YGMN----NGGKN-------YKNRLQAQGIYLDFldEPVDSL-RRKREGTYASYIFGsdgKRVKLILLDTRSHLQWGT-------------DCDIL 203 5433....22222.......3445667777888844599887.77888999999996333689********9876555.............5679* PP PhoD 188 GeeQeewLkrelkasrat.WkviaqqvliskvdekaeegelevnadawdGyaaeRerllraikeakirnvvvLtGDvHsawasdl 271 G+eQ ewL +l++++ + vi++ + + + + +d+w + + +rl+ ++++ v++L+GDvH + l FUN_001054-T1 204 GKEQWEWLEMQLSDTNPAqLTVIGSGIQVLSDT---------PYTDKWISCPSSYDRLMWLLQRNP--RVILLSGDVHFGEFACL 277 *************887665******99874433.........2589****************9988..9*********8766666 PP >> Metallophos Calcineurin-like phosphoesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 7.5e-05 0.96 21 104 .. 63 162 .. 53 272 .. 0.50 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 7.5e-05 Metallophos 21 lleklrpeekpdlvliaGD..lvdrg.....................sletevlellallvkyipvflvrGNHd...fydeclrkygelnll...a 87 l+e++ ++ kpdl +++GD + d +++ e++++l++ + v+G d + ++ + +++++ + FUN_001054-T1 63 LWEHISKQ-KPDLWVWLGDavYADTKiapltwtpsplvemvgkfnalKYSLEYQKFLESG------IHVLGVWDdhdY--GMNNGGKNYKNRlqaQ 149 77888788.**********77777779999888875444444433333333333333333......556666663222..2222222222222223 PP Metallophos 88 rpwkafvevfnllplaa 104 +++ +f p+ + FUN_001054-T1 150 GIYLDF----LDEPVDS 162 333333....3333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (449 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 577 (0.0225876); expected 510.9 (0.02) Passed bias filter: 480 (0.0187904); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4418.76 // Query: FUN_001055-T1 [L=444] Description: FUN_001055 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-05 25.4 0.0 3.2e-05 24.5 0.0 1.4 1 UBX UBX domain ------ inclusion threshold ------ 0.48 10.6 6.8 0.7 10.1 6.8 1.2 1 RR_TM4-6 Ryanodine Receptor TM 4-6 1 9.2 7.9 1.5 8.7 7.9 1.1 1 DNA_methylase C-5 cytosine-specific DNA methylase 5 6.9 12.8 7.3 6.4 12.8 1.2 1 BTV_NS2 Bluetongue virus non-structural protein NS2 Domain annotation for each model (and alignments): >> UBX UBX domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.0 5e-09 3.2e-05 6 51 .. 305 349 .. 300 357 .. 0.87 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 5e-09 UBX 6 vtrlqiRlpdGsrlvrrFnssdklqsvydfvdskrydeeepfsLlt 51 t++ iR+ dG+r r+F++++ q+vyd++ s + + f+L++ FUN_001055-T1 305 GTTIVIRCNDGERVHRKFQENACFQEVYDWLGSLEDIPLY-FTLQR 349 689***************************8887766666.88876 PP >> RR_TM4-6 Ryanodine Receptor TM 4-6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 6.8 0.00011 0.7 43 159 .. 164 285 .. 142 304 .. 0.49 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00011 RR_TM4-6 43 llsdifgldlkkeggqyklvkkdaeag.Lgdlsettaeetp........pelkkklq........eeeeaedekeeeeepkaee.ekadsedgeke 120 + d+ g d+k++ + +++++a+ Lg++s+t +e+++ + +++++e++++ ++e k++e e a + +e FUN_001055-T1 164 KVIDLYGGDQKQDRLLFLAPSTGRNATlLGEISDTDTESNQidsmlkkiI------EraelrimgQRQQREQYATWRRERKEQEeEFARVQTQEYG 253 56788899999999988888888888745999999998888764444320......2332333332233333322222222222122222222211 PP RR_TM4-6 121 ekekeeeeeeeeeeeekkkkkkrkskkkeeaeaqesafl 159 + ++e e+e+++ k ++ s+ k ++e+qe++ FUN_001055-T1 254 KGNQE-------EQEQETNKDTEVSRIKGNQEEQEQETN 285 11111.......111111111111111111122222211 PP >> DNA_methylase C-5 cytosine-specific DNA methylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 7.9 0.00023 1.5 147 282 .. 169 300 .. 166 303 .. 0.69 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00023 DNA_methylase 147 yGvpQnReRvfivgirkdleln.lskvkefrfpkkkdleakktlkdlleekldenktalsdklvekeerrkkttkaseegysellrnrvdkveelk 241 yG Q+ +R+ +++ ++++ l +++++++++++ + + lk++ e e + ++++++ e+++++++++k++ee+++ + + + k ++ + FUN_001055-T1 169 YGGDQKQDRLLFLAPSTGRNATlLGEISDTDTESNQ---IDSMLKKIIER--AELRIMGQRQQREQYATWRRERKEQEEEFARVQTQEYGKGNQEE 259 88899999**99999999988877788888888886...899*******8..8*****************************66666445555444 PP DNA_methylase 242 tlsatvrksgrkelaktgklqknkekfk...gekkniRrLtprE 282 ++++t ++++ + ++ +q+++e+ e ++RrL + E FUN_001055-T1 260 QEQETNKDTE---VSRIKGNQEEQEQETnkdTEIRKARRLMTSE 300 4444444444...3333333333332222234445555555444 PP >> BTV_NS2 Bluetongue virus non-structural protein NS2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 12.8 0.0011 7.3 170 262 .. 199 293 .. 196 326 .. 0.57 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0011 BTV_NS2 170 eerrekieealesgatrsegRllGlraekvaklevkeeve..kpkvkrteksswsesveseekssdeeeeeakev..aeqsdpesevkdekkepsv 261 ++++++i++ l+ +r+e R++G r+++ + + + e + +++ r++++++ + ++e+++++++++e +++ +++++++++ kd e+ FUN_001055-T1 199 DTESNQIDSMLKKIIERAELRIMGQRQQREQYATWRRERKeqEEEFARVQTQEYGKGNQEEQEQETNKDTEVSRIkgNQEEQEQETNKD--TEIRK 292 678899*******************9997776666665553355555555555555544444222222233332343222221112221..11211 PP BTV_NS2 262 a 262 a FUN_001055-T1 293 A 293 1 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (444 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2150 (0.0841652); expected 510.9 (0.02) Passed bias filter: 817 (0.0319828); expected 510.9 (0.02) Passed Vit filter: 98 (0.00383637); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.47s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 4312.42 // Query: FUN_001056-T1 [L=371] Description: FUN_001056 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-13 52.2 38.6 8.6e-08 33.3 7.9 3.2 3 zf-TRAF TRAF-type zinc finger 3.9e-07 30.3 6.4 3.9e-07 30.3 6.4 3.7 4 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 2.6e-05 24.6 8.0 2.6e-05 24.6 8.0 3.3 3 zf-RING_UBOX RING-type zinc-finger 5.2e-05 23.6 7.4 5.2e-05 23.6 7.4 3.7 2 zf-RING_5 zinc-RING finger domain 0.00015 22.3 9.1 0.00015 22.3 9.1 3.1 2 zf-C3HC4_4 zinc finger of C3HC4-type, RING 0.0011 19.5 8.6 0.0011 19.5 8.6 4.7 3 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING 0.0086 17.1 14.5 0.0086 17.1 14.5 3.2 3 zf-TRAF_2 TRAF-like zinc-finger ------ inclusion threshold ------ 0.012 16.3 0.3 0.3 11.8 0.0 3.0 3 U-box U-box domain 0.052 14.2 0.0 0.66 10.7 0.0 2.7 3 MATH_2 MATH domain Domain annotation for each model (and alignments): >> zf-TRAF TRAF-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.8 3.7 1e+04 14 50 .. 39 44 .. 32 65 .. 0.50 2 ! 30.5 15.3 2.2e-10 6.2e-07 1 60 [] 104 158 .. 104 158 .. 0.98 3 ! 33.3 7.9 3e-11 8.6e-08 3 60 .] 161 214 .. 159 214 .. 0.94 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 3.7 zf-TRAF 14 necckkkilRedlkdHlekdCkkaevkCkfkevGCke 50 + +GC e FUN_001056-T1 39 H-------------------------------SGCRE 44 3...............................33332 PP == domain 2 score: 30.5 bits; conditional E-value: 2.2e-10 zf-TRAF 1 HletCpfapvpCpnecckkkilRedlkdHlekdCkkaevkCkfkevGCkekvkrealqkH 60 H ++Cp+ +v C+ne c++k +Re++++H++ +C+k +++C+ C++ vk e lqkH FUN_001056-T1 104 HFKKCPKLQVVCNNEECQHKSIREEMPNHIA-SCSKKKIPCSE----CHVCVKWELLQKH 158 899****************************.***********....************9 PP == domain 3 score: 33.3 bits; conditional E-value: 3e-11 zf-TRAF 3 etCpfapvpCpnecckkkilRedlkdHlekdCkkaevkCkfkevGCkekvkrealqkH 60 e+Cp a ++Cp +c+ + i+R ++ Hl+ +C++ Ck GCk+++kr++l +H FUN_001056-T1 161 EQCPNAVIQCPLDCGST-IPRSSITLHLH-QCPEKVCLCKV--PGCKKMMKRKDLTSH 214 79**********99966.***********.*****999988..************999 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 6.4 1.4e-10 3.9e-07 3 46 .. 20 65 .. 18 67 .. 0.94 2 ? -5.4 7.6 9 2.6e+04 22 42 .. 132 149 .. 113 153 .. 0.69 3 ? -6.6 8.0 9 2.6e+04 26 40 .. 146 164 .. 140 181 .. 0.60 4 ? -3.8 1.8 5.8 1.6e+04 23 27 .. 194 198 .. 184 209 .. 0.54 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 1.4e-10 zf-C3HC4_3 3 eeCviClerernvvllpCgHlclCeeCaeklr...kkkkCpiCrqki 46 +C iC+++ + v l CgH C+eC ++l +kCp+Cr++ FUN_001056-T1 20 LQCSICYSTMLKPVSLGCGHS-GCRECLTELVtktLMPKCPMCRTEL 65 69*******************.**********99999*******986 PP == domain 2 score: -5.4 bits; conditional E-value: 9 zf-C3HC4_3 22 HlclCeeCaeklrkkkkCpiC 42 H++ C++k +++C++C FUN_001056-T1 132 HIAS---CSKKKIPCSECHVC 149 5544...44444455888888 PP == domain 3 score: -6.6 bits; conditional E-value: 9 zf-C3HC4_3 26 CeeCaeklr....kkkkCp 40 C+ C + + ++Cp FUN_001056-T1 146 CHVCVKWELlqkhQAEQCP 164 3333333224345555555 PP == domain 4 score: -3.8 bits; conditional E-value: 5.8 zf-C3HC4_3 23 lclCe 27 +clC+ FUN_001056-T1 194 VCLCK 198 33333 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 8.0 9.2e-09 2.6e-05 1 39 [] 22 59 .. 22 65 .. 0.84 2 ? -1.9 3.3 1.8 5.1e+03 21 39 .] 146 164 .. 142 164 .. 0.74 3 ? -3.6 0.6 5.8 1.6e+04 15 25 .. 173 183 .. 166 191 .. 0.59 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 9.2e-09 zf-RING_UBOX 1 CpICleeftdPlv.lpCGHtfCreClwelskkekgkikCP 39 C+IC+ ++ +P v l CGH+ CreCl ++ kCP FUN_001056-T1 22 CSICYSTMLKP-VsLGCGHSGCRECL-TELVTKTLMPKCP 59 ***********.758***********.4555566666666 PP == domain 2 score: -1.9 bits; conditional E-value: 1.8 zf-RING_UBOX 21 CreClwelskkekgkikCP 39 C+ C+++ ++++ +CP FUN_001056-T1 146 CHVCVKWELLQKHQAEQCP 164 8888855677777777787 PP == domain 3 score: -3.6 bits; conditional E-value: 5.8 zf-RING_UBOX 15 pCGHtfCreCl 25 +CG t+ r+ + FUN_001056-T1 173 DCGSTIPRSSI 183 56655555555 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 7.4 1.8e-08 5.2e-05 1 43 [] 21 63 .. 21 63 .. 0.93 2 ? -11.0 14.5 9 2.6e+04 18 41 .. 134 149 .. 114 176 .. 0.58 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 1.8e-08 zf-RING_5 1 hCnkCfkelsktrkfyltsCgHifCeeClkkll...eerqCpiCkk 43 +C++C++ k++ + CgH+ C eCl++l +Cp+C++ FUN_001056-T1 21 QCSICYSTM---LKPVSLGCGHSGCRECLTELVtktLMPKCPMCRT 63 599999999...*********************999999*****96 PP == domain 2 score: -11.0 bits; conditional E-value: 9 zf-RING_5 18 tsC..gHifCeeClkklleerqCpiC 41 sC + i C eC ++C FUN_001056-T1 134 ASCskKKIPCSEC----------HVC 149 4443333444444..........444 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 9.1 5.1e-08 0.00015 1 42 [] 22 61 .. 22 61 .. 0.93 2 ? -4.8 4.9 9 2.6e+04 19 33 .. 144 159 .. 139 174 .. 0.53 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 5.1e-08 zf-C3HC4_4 1 CpvCldyLekPvsieCGhsfClsCisslqkepdgesllCplC 42 C +C + + kPvs+ CGhs C++C+ +l + Cp+C FUN_001056-T1 22 CSICYSTMLKPVSLGCGHSGCRECLTELVTKTLM--PKCPMC 61 9***************************998877..478888 PP == domain 2 score: -4.8 bits; conditional E-value: 9 zf-C3HC4_4 19 sfClsCis.slqkepd 33 s C C+ +l ++ + FUN_001056-T1 144 SECHVCVKwELLQKHQ 159 4455555423333333 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 8.6 3.8e-07 0.0011 2 54 .. 22 64 .. 21 67 .. 0.90 2 ? -7.5 13.0 9 2.6e+04 22 54 .. 143 177 .. 107 180 .. 0.76 3 ? -0.5 1.1 0.66 1.9e+03 5 21 .. 190 206 .. 188 220 .. 0.85 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 3.8e-07 RING_XB3-XBAT31 2 CsiCferactieveeCgHqlCaqCalalcskkkkteaataskespaCPfCRss 54 CsiC++ + + + +CgH+ C +C +l++k p CP+CR++ FUN_001056-T1 22 CSICYSTMLKPVSLGCGHSGCRECLTELVTKT----------LMPKCPMCRTE 64 ****************************9984..........3578*****87 PP == domain 2 score: -7.5 bits; conditional E-value: 9 RING_XB3-XBAT31 22 CaqCalalc.skkkkteaataskespaCPf.CRss 54 C +C +++ + +k +a++ ++ ++CP+ C s+ FUN_001056-T1 143 CSECHVCVKwELLQKHQAEQCPNAVIQCPLdCGST 177 66676664313335566777888889999866665 PP == domain 3 score: -0.5 bits; conditional E-value: 0.66 RING_XB3-XBAT31 5 CferactieveeCgHql 21 C e++c +v +C + FUN_001056-T1 190 CPEKVCLCKVPGCKKMM 206 88999999999997655 PP >> zf-TRAF_2 TRAF-like zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 8.4 0.18 5e+02 2 87 .. 40 118 .. 34 121 .. 0.71 2 ? 4.2 12.1 0.031 89 25 85 .. 85 144 .. 57 146 .. 0.83 3 ! 17.1 14.5 3e-06 0.0086 3 80 .. 145 221 .. 143 233 .. 0.84 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.18 zf-TRAF_2 2 ehcekclkkkckvkveesescalisckekcgavlhsckeeehkllcpkekvpclnaeyGcPltlkrkklakhlevcpasvvlcsve 87 + c++cl++ +++ +c + + + + c + + ++ v+cl+ Gc + + + +h+++cp v+c+ e FUN_001056-T1 40 SGCRECLTELVTKT--LMPKCPMCRTELRADS---ICVNIALDHITSELAVECLS--VGCGWKGSYGQAPEHFKKCPKLQVVCNNE 118 55666665554444..4455665444444333...46666666688899999986..69999999******************876 PP == domain 2 score: 4.2 bits; conditional E-value: 0.031 zf-TRAF_2 25 isc.kekcgavlhsckeeehkllcpkekvpclnaeyGcPltlkrkklakhlevcpasvvlcs 85 ++c + cg ++ eh cpk +v c n e c ++ r+++ +h+ +c+ + cs FUN_001056-T1 85 VEClSVGCGWKGSYGQAPEHFKKCPKLQVVCNNEE--CQHKSIREEMPNHIASCSKKKIPCS 144 455356788888888999*************9986..9*******************99998 PP == domain 3 score: 17.1 bits; conditional E-value: 3e-06 zf-TRAF_2 3 hcekclkkkckvkveesesc..alisckekcgavlhsckeeehkllcpkekvpclnaeyGcPltlkrkklakhlevcpas 80 +c+ c+k + +k +++e+c a+i+c+ +cg ++ + + h cp++ cl++ Gc ++krk+l++h+ ++s FUN_001056-T1 145 ECHVCVKWELLQK-HQAEQCpnAVIQCPLDCGSTIPRSSITLHLHQCPEK--VCLCKVPGCKKMMKRKDLTSHIMEAASS 221 7999999887666.556667447************************976..6999*****************9877665 PP >> U-box U-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.0001 0.3 4 60 .. 19 76 .. 16 81 .. 0.92 2 ? 0.7 0.0 0.29 8.2e+02 23 37 .. 175 189 .. 168 216 .. 0.76 3 ? -2.5 0.0 3 8.4e+03 7 27 .. 277 297 .. 276 316 .. 0.55 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.0001 U-box 4 efldpitlelmkdPvilpsgvtvdrstierhlls.kdktdPftrepltqdqlipnlel 60 + ++i + m +Pv l g++ r+ +++ + + + +P+ r+ l d + n++l FUN_001056-T1 19 QLQCSICYSTMLKPVSLGCGHSGCRECLTELVTKtLMPKCPMCRTELRADSICVNIAL 76 578***************************99995689**************999987 PP == domain 2 score: 0.7 bits; conditional E-value: 0.29 U-box 23 gvtvdrstierhlls 37 g t+ rs+i+ hl++ FUN_001056-T1 175 GSTIPRSSITLHLHQ 189 789999999999998 PP == domain 3 score: -2.5 bits; conditional E-value: 3 U-box 7 dpitlelmkdPvilpsgvtvd 27 dpit+e++++ +g d FUN_001056-T1 277 DPITSEVFSCERHKWRGLLTD 297 677777776544444444444 PP >> MATH_2 MATH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 2.9 8.3e+03 56 80 .. 133 157 .. 101 169 .. 0.57 2 ? -1.9 0.0 1.8 5.1e+03 109 121 .. 201 213 .. 191 217 .. 0.88 3 ? 10.7 0.0 0.00023 0.66 2 108 .. 256 343 .. 255 355 .. 0.79 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.9 MATH_2 56 ladgendallewpvkakftlslldq 80 +a++++++ +++++ ++ ll++ FUN_001056-T1 133 IASCSKKKIPCSECHVCVKWELLQK 157 3333343344444444444444444 PP == domain 2 score: -1.9 bits; conditional E-value: 1.8 MATH_2 109 GfskfisleeLed 121 G++k++++++L + FUN_001056-T1 201 GCKKMMKRKDLTS 213 9999999999987 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00023 MATH_2 2 fvwkIenfskllkea....kgekieSptFyvggykwrlrlypnGngsesgdylSlyLaladgendallewpvkakftlslldqkekeksvskeikt 93 f w+ nf +l+++ ++ i+S++F+ +++kwr l + Sl+L+l++ + p+ a+f+++l+ +ek+k++++e +t FUN_001056-T1 256 FRWRLLNFPAMLRDQtdatGDDPITSEVFSCERHKWRGLLTDK---------KSLFLQLVSASH------PITAEFRIVLMPGQEKQKEFRSEKTT 336 78999999999888888878889*************9777666.........49******9998......9**********999766665554443 PP MATH_2 94 dpvksfsrperksgw 108 + ++ +w FUN_001056-T1 337 L-----K---EGEMW 343 3.....2...24555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (371 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1102 (0.0431396); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3548.96 // Query: FUN_001057-T1 [L=121] Description: FUN_001057 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1024 (0.0400861); expected 510.9 (0.02) Passed bias filter: 561 (0.0219612); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1183.59 // Query: FUN_001058-T1 [L=67] Description: FUN_001058 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (67 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 459 (0.0179683); expected 510.9 (0.02) Passed bias filter: 382 (0.014954); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.34s 00:00:00.60 Elapsed: 00:00:00.40 # Mc/sec: 677.70 // Query: FUN_001059-T1 [L=333] Description: FUN_001059 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-43 148.8 0.0 5.2e-43 148.3 0.0 1.2 1 PhyH Phytanoyl-CoA dioxygenase (PhyH) ------ inclusion threshold ------ 0.041 13.1 0.0 30 3.7 0.0 2.9 3 Gig2-like Gig2-like 0.054 14.2 0.0 0.12 13.0 0.0 1.6 1 Gp44_lid Sliding-clamp-loader large subunit, AAA+ ATPase li Domain annotation for each model (and alignments): >> PhyH Phytanoyl-CoA dioxygenase (PhyH) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 148.3 0.0 6.2e-47 5.2e-43 1 213 [] 55 271 .. 55 271 .. 0.93 Alignments for each domain: == domain 1 score: 148.3 bits; conditional E-value: 6.2e-47 PhyH 1 feedGylviegvlspeevealraelerlldraleseedkddffdekaagdedklleksetkvdhflhp......keladlvrailgspvyvanvlq 90 ++++Gylv+++++++++++++ +++++++ + +++++++d k+++ ++ ++e+ +k + f ++ +el ++++++ + + +a ++ FUN_001059-T1 55 YNKNGYLVVRNLVPADMLNRFVERFHEICSGDILV-PGMTVMKDVKHVKWNSPMSERTVNKLQNFEEDevlfsyCELPQILKYVTCFTGPDAKSVH 149 799*************************7777776.699*********************************997777777777777777777788 PP PhyH 91 smyqdesifkepktGaev..qpwHqDdtflptrpresvvnvwialddateenGclrviPGSHkweegplerrlpeddaeae...ddeadkedeeea 181 +m+ i+k+p++G+++ +p+HqD +++p+rp +++v+ w+a++++ + nGcl v+PGSH + +l++++p+++ + ++++d +++ + FUN_001059-T1 150 TML----INKPPDPGTKTsrHPLHQDLHYFPFRPANRIVCSWTAMEKVDKRNGCLVVLPGSHYS--PLLQHHYPKWEGGVNamyHGIKDCDSNIPL 239 999....*********************************************************..877888888887777*************** PP PhyH 182 vpvelkaGdvvlfhprlvHgsgaNrsdksRra 213 ++e++aGd+v+fhp l+HgsgaN++++ R+a FUN_001059-T1 240 LHLEMNAGDTVFFHPLLIHGSGANTTNRLRKA 271 ****************************9986 PP >> Gig2-like Gig2-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.0035 30 64 103 .. 48 87 .. 40 118 .. 0.74 2 ? 3.5 0.0 0.004 34 235 258 .. 182 205 .. 164 210 .. 0.91 3 ? 2.1 0.0 0.011 91 316 342 .. 243 269 .. 235 299 .. 0.71 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.0035 Gig2-like 64 seeklaeikrrGvlvirgvvpkeealkwkeeikeYleknd 103 +ee+ + ++ G lv+r+ vp + +++ e +e ++ FUN_001059-T1 48 TEEQVHFYNKNGYLVVRNLVPADMLNRFVERFHEICSGDI 87 5677777899*************99999998888776664 PP == domain 2 score: 3.5 bits; conditional E-value: 0.004 Gig2-like 235 RtfQGwlalsdvkpgeGtlrvlPl 258 R +w+a+ +v +++G l vlP FUN_001059-T1 182 RIVCSWTAMEKVDKRNGCLVVLPG 205 66779*****************95 PP == domain 3 score: 2.1 bits; conditional E-value: 0.011 Gig2-like 316 eveaGdyvfWhcDlihsvdkehegkgd 342 e++aGd+vf h+ lih +++++ FUN_001059-T1 243 EMNAGDTVFFHPLLIHGSGANTTNRLR 269 689*************87666655554 PP >> Gp44_lid Sliding-clamp-loader large subunit, AAA+ ATPase lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 1.5e-05 0.12 4 56 .. 70 123 .. 68 126 .. 0.88 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.5e-05 Gp44_lid 4 smmkemivRcmaICeeEgievedkkviaaL..VkkNFPdfRktineldkYsskgv 56 m+ + R +IC +i v + v++ Vk N P +t+n+l+++ + v FUN_001059-T1 70 DMLNRFVERFHEICS-GDILVPGMTVMKDVkhVKWNSPMSERTVNKLQNFEEDEV 123 6889999*******7.58*********98666*****************988766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (333 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 841 (0.0329223); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3203.65 // Query: FUN_001061-T1 [L=879] Description: FUN_001061 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-32 111.7 0.2 9.8e-32 110.2 0.1 1.9 2 Transglut_N Transglutaminase family 4e-14 53.1 0.0 4.2e-08 33.7 0.0 2.3 2 Transglut_C Transglutaminase family, C-terminal ig like d 1.3e-11 45.2 0.1 3.1e-11 44.0 0.1 1.6 1 Transglut_core Transglutaminase-like superfamily Domain annotation for each model (and alignments): >> Transglut_N Transglutaminase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.2 0.1 1.2e-35 9.8e-32 3 113 .. 190 305 .. 188 306 .. 0.92 2 ? -3.3 0.0 1.9 1.6e+04 60 99 .. 636 673 .. 623 680 .. 0.52 Alignments for each domain: == domain 1 score: 110.2 bits; conditional E-value: 1.2e-35 Transglut_N 3 vdlqkeeNnkeHhTdeysskelvvRRGqpFkitlkfnrpfdpskdklslevetgpkpseskgtkavfpl..seeedeskWsakveeseg...nslt 93 + l+ +eN+++HhTd+y++++l+vRRGq+F+ tl+fnr+f+++kd l l++ +g p+eskgt +++p+ ++e +++ W ak++++++ ++++ FUN_001061-T1 190 IALHETENRRNHHTDKYENSSLIVRRGQSFDATLTFNRAFNSKKDDLVLQFAVGCGPKESKGTLIRVPVnrDREFARDVWLAKFTQRQNdgeTVTR 285 67899****************************************************************6666677889******76665555899 PP Transglut_N 94 lsvtspanapiGrYklsvev 113 +++t+pana++GrY+l ve+ FUN_001061-T1 286 VQITPPANAIVGRYNLFVET 305 ****************9998 PP == domain 2 score: -3.3 bits; conditional E-value: 1.9 Transglut_N 60 seskgtkavfplseeedeskWsakveesegnsltlsvtsp 99 +e + +++ ++s+++d+++ s + +e+ +++s p FUN_001061-T1 636 QERRAVQMAYKFSSRKDQRHQSLYTLPTED--VKFSFEVP 673 344444445555555555555555553333..44555555 PP >> Transglut_C Transglutaminase family, C-terminal ig like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.7 0.0 5e-12 4.2e-08 1 100 [. 666 765 .. 666 770 .. 0.94 2 ! 17.2 0.0 6.9e-07 0.0059 1 104 [. 779 877 .. 779 879 .] 0.90 Alignments for each domain: == domain 1 score: 33.7 bits; conditional E-value: 5e-12 Transglut_C 1 pelkievlesavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpskyGprkllve..lssdala 94 +++++ev++ +++g tv + +kN+ +++ ++vk +++ + +y+G+ + k++s+e+ LeP +ek + l++ ps y k+ ++ l++ ++a FUN_001061-T1 666 VKFSFEVPDVLPIGETATVGLKMKNTMHQS-RTVKGMITGVMGFYTGICCKDLKEESFEMWLEPRQEKFYFLEFPPSLY-LGKCEADggLKIYVMA 759 5799**************************.***********************************************9.8888888999999999 PP Transglut_C 95 kvkglk 100 +vk+ + FUN_001061-T1 760 TVKENG 765 999876 PP == domain 2 score: 17.2 bits; conditional E-value: 6.9e-07 Transglut_C 1 pelkiev.lesavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpskyGprkllvelssdalak 95 p++kiev +++++vg++l++ ++++Npl+ ++ + + +e +G + k +++t+ ++ +++++k++p + G + + ++s +l FUN_001061-T1 779 PDIKIEVvRGRPQVGNELEFKLSFSNPLPVRISG-----GKWYIETTGAN-PKTKIIPNTITVAQGADVETPFKLTPYREGLCRVSATFRSHVLSG 868 67888853799********************766.....99********5.8999999************************999999******** PP Transglut_C 96 vkglkevlv 104 v+g ++ ++ FUN_001061-T1 869 VRGHGNLQI 877 **9988766 PP >> Transglut_core Transglutaminase-like superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.0 0.1 3.6e-15 3.1e-11 50 108 .] 458 544 .. 433 544 .. 0.91 Alignments for each domain: == domain 1 score: 44.0 bits; conditional E-value: 3.6e-15 Transglut_core 50 kkGncedfaslfvallRalGipaRlvtgylagede.....................vrsedaHawaevyl.......dgggWvpvDp 108 k ++c+ f+ l+++llRa+Gip+R vt++++++d+ + +++H+w+e ++ +gW+++D+ FUN_001061-T1 458 KYAQCWVFSGLVTTLLRAIGIPTRSVTNFASAHDTdasmtidfhfdeqgkplkhldDSIWNFHVWNESWFkrpdlpdGHDGWQAFDA 544 3499*****************************99*********************999*************999877788***996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (879 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 532 (0.020826); expected 510.9 (0.02) Passed bias filter: 429 (0.0167939); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.41s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 8385.55 // Query: FUN_001061-T2 [L=937] Description: FUN_001061 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-32 111.6 0.2 1.1e-31 110.1 0.1 1.9 2 Transglut_N Transglutaminase family 4.7e-14 52.9 0.0 4.6e-08 33.6 0.0 2.3 2 Transglut_C Transglutaminase family, C-terminal ig like d 1.5e-11 45.0 0.1 3.3e-11 43.9 0.1 1.6 1 Transglut_core Transglutaminase-like superfamily Domain annotation for each model (and alignments): >> Transglut_N Transglutaminase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.1 0.1 1.3e-35 1.1e-31 3 113 .. 248 363 .. 246 364 .. 0.92 2 ? -3.4 0.0 2.1 1.8e+04 60 99 .. 694 731 .. 682 738 .. 0.52 Alignments for each domain: == domain 1 score: 110.1 bits; conditional E-value: 1.3e-35 Transglut_N 3 vdlqkeeNnkeHhTdeysskelvvRRGqpFkitlkfnrpfdpskdklslevetgpkpseskgtkavfpl..seeedeskWsakveeseg...nslt 93 + l+ +eN+++HhTd+y++++l+vRRGq+F+ tl+fnr+f+++kd l l++ +g p+eskgt +++p+ ++e +++ W ak++++++ ++++ FUN_001061-T2 248 IALHETENRRNHHTDKYENSSLIVRRGQSFDATLTFNRAFNSKKDDLVLQFAVGCGPKESKGTLIRVPVnrDREFARDVWLAKFTQRQNdgeTVTR 343 67899****************************************************************6666677889******76665555899 PP Transglut_N 94 lsvtspanapiGrYklsvev 113 +++t+pana++GrY+l ve+ FUN_001061-T2 344 VQITPPANAIVGRYNLFVET 363 ****************9998 PP == domain 2 score: -3.4 bits; conditional E-value: 2.1 Transglut_N 60 seskgtkavfplseeedeskWsakveesegnsltlsvtsp 99 +e + +++ ++s+++d+++ s + +e+ +++s p FUN_001061-T2 694 QERRAVQMAYKFSSRKDQRHQSLYTLPTED--VKFSFEVP 731 344444445555555555555555553333..44454455 PP >> Transglut_C Transglutaminase family, C-terminal ig like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.6 0.0 5.4e-12 4.6e-08 1 100 [. 724 823 .. 724 828 .. 0.94 2 ! 17.1 0.0 7.6e-07 0.0065 1 104 [. 837 935 .. 837 937 .] 0.90 Alignments for each domain: == domain 1 score: 33.6 bits; conditional E-value: 5.4e-12 Transglut_C 1 pelkievlesavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpskyGprkllve..lssdala 94 +++++ev++ +++g tv + +kN+ +++ ++vk +++ + +y+G+ + k++s+e+ LeP +ek + l++ ps y k+ ++ l++ ++a FUN_001061-T2 724 VKFSFEVPDVLPIGETATVGLKMKNTMHQS-RTVKGMITGVMGFYTGICCKDLKEESFEMWLEPRQEKFYFLEFPPSLY-LGKCEADggLKIYVMA 817 5799**************************.***********************************************9.8888888999999999 PP Transglut_C 95 kvkglk 100 +vk+ + FUN_001061-T2 818 TVKENG 823 999876 PP == domain 2 score: 17.1 bits; conditional E-value: 7.6e-07 Transglut_C 1 pelkiev.lesavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpskyGprkllvelssdalak 95 p++kiev +++++vg++l++ ++++Npl+ ++ + + +e +G + k +++t+ ++ +++++k++p + G + + ++s +l FUN_001061-T2 837 PDIKIEVvRGRPQVGNELEFKLSFSNPLPVRISG-----GKWYIETTGAN-PKTKIIPNTITVAQGADVETPFKLTPYREGLCRVSATFRSHVLSG 926 67888853799********************766.....99********5.8999999************************999999******** PP Transglut_C 96 vkglkevlv 104 v+g ++ ++ FUN_001061-T2 927 VRGHGNLQI 935 **9988766 PP >> Transglut_core Transglutaminase-like superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.9 0.1 3.9e-15 3.3e-11 50 108 .] 516 602 .. 491 602 .. 0.91 Alignments for each domain: == domain 1 score: 43.9 bits; conditional E-value: 3.9e-15 Transglut_core 50 kkGncedfaslfvallRalGipaRlvtgylagede.....................vrsedaHawaevyl.......dgggWvpvDp 108 k ++c+ f+ l+++llRa+Gip+R vt++++++d+ + +++H+w+e ++ +gW+++D+ FUN_001061-T2 516 KYAQCWVFSGLVTTLLRAIGIPTRSVTNFASAHDTdasmtidfhfdeqgkplkhldDSIWNFHVWNESWFkrpdlpdGHDGWQAFDA 602 3499*****************************99*********************999*************999877788***996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (937 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 615 (0.0240752); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 8819.67 // Query: FUN_001062-T1 [L=313] Description: FUN_001062 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-07 29.7 0.0 6.1e-07 29.3 0.0 1.2 1 LigB Catalytic LigB subunit of aromatic ring-opening dio Domain annotation for each model (and alignments): >> LigB Catalytic LigB subunit of aromatic ring-opening dioxygenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.0 2.4e-11 6.1e-07 18 259 .. 47 297 .. 25 307 .. 0.79 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 2.4e-11 LigB 18 eeqeelrekvikgyeeiseriaekrPdtiivvsphhlvdinpvfvlgvaeefeaiddfn.......kfirrvkfelkgnpeLakkiaealkkdgid 106 +++++ + v ++ ++++ i + +Pd+i+v sph+ + + f+ + + +++d + ++v+++ +g L + ++ + +k FUN_001062-T1 47 TAKAQAWL-VHDSAVQVGKHIEDLKPDAIVVSSPHGIAAPE-DFIFYFSPKGFGFSDTDncacppcCYNLSVAMDTNGVEVLVSTLKDEKEKVSYL 140 55556555.77888899********************9444.566666666666666556999988888999999999999999999887777666 PP LigB 107 ltvv....estslklDHGtlvPLrfmnk...nvkvikviintvlyp..vlsferlyrLGeAlrraieeyedknvlvlgsGglsHqleedraakeda 193 ++ e+ l +G +vPL+f + + kvi ++ + y+ v+ +l +LG+ + +++ + ++++++++ s +l H+ + ++++ + FUN_001062-T1 141 SAFGppgkEDMPFPLRWGEVVPLYFAKNalgHSKVIVLSQPSRRYTksVQMIPELTQLGRKMFKILHS-QPEKIVIIISADLAHTHLKSGPYGFST 235 54448888999***************996776666666666655552255666899**********88.8**********************9998 PP LigB 194 eaneefDkelldlLkegrveellkmekeeaeeaagkeeeefvdllvllGalgedkaevrkellsye 259 a+e fDk+ + + + ll+ ++++a +++f l++l G+l ++ + ++ll++ FUN_001062-T1 236 -AAEPFDKACGTWVTTQKSASLLNEAAFYVDKA---LSCGFTGLVMLDGLLKASPTVWDSHLLANF 297 .*********99999999997776665555555...6**************987666777776655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (313 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 655 (0.025641); expected 510.9 (0.02) Passed bias filter: 575 (0.0225093); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3008.12 // Query: FUN_001063-T1 [L=157] Description: FUN_001063 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.8e-35 120.0 0.0 1.1e-34 119.7 0.0 1.1 1 Roc Ras of Complex, Roc, domain of DAPkinase 1.5e-33 116.2 0.0 1.8e-33 115.9 0.0 1.1 1 Ras Ras family 2.3e-08 34.2 0.0 3.1e-08 33.8 0.0 1.1 1 Arf ADP-ribosylation factor family 1.9e-06 28.5 0.0 2.4e-06 28.1 0.0 1.1 1 MMR_HSR1 50S ribosome-binding GTPase 2.8e-06 27.5 0.0 0.00012 22.2 0.0 2.0 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.00014 21.8 0.0 0.00018 21.5 0.0 1.1 1 Gtr1_RagA Gtr1/RagA G protein conserved region ------ inclusion threshold ------ 0.022 14.7 0.0 0.045 13.7 0.0 1.5 2 TniB Bacterial TniB protein 0.057 13.0 0.0 0.15 11.7 0.0 1.7 2 G-alpha G-protein alpha subunit 0.11 12.9 0.1 0.19 12.2 0.1 1.3 1 MMR_HSR1_Xtn C-terminal region of MMR_HSR1 domain 0.21 11.6 0.0 0.32 11.0 0.0 1.2 1 AAA_7 P-loop containing dynein motor region Domain annotation for each model (and alignments): >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 119.7 0.0 4.2e-38 1.1e-34 1 119 [] 24 137 .. 24 137 .. 0.92 Alignments for each domain: == domain 1 score: 119.7 bits; conditional E-value: 4.2e-38 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd.sr..sse 93 Kv++lGds+vGK++l++rf+ d +++++ st+++++++ ++ ++g +++++++WDtaGqerf+s+hp+yy++a+ ++lvfd +r +++ FUN_001063-T1 24 KVICLGDSAVGKSKLVERFLMDGYKPQQLSTYALTLFQYKT-LVDG-------TDVRVDFWDTAGQERFSSMHPSYYHQAHSCLLVFDiTRkvTYK 111 9***********************************99875.3444.......6799*******************************84434789 PP Roc 94 nlkeWlkelkevagkspvilvgnkiD 119 nl +W+kel+++++++p+i+++nkiD FUN_001063-T1 112 NLAKWYKELRDYRENIPCIVIANKID 137 *************************9 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 115.9 0.0 7.2e-37 1.8e-33 1 115 [. 24 137 .. 24 143 .. 0.98 Alignments for each domain: == domain 1 score: 115.9 bits; conditional E-value: 7.2e-37 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwlee 96 k++ +Gds+vGKs l+ rf+ + +k ++ sT ++ ++ vdg++v+++ wDTAGqerf++++++yy++a+ +llv+dit++ +++n++kw++e FUN_001063-T1 24 KVICLGDSAVGKSKLVERFLMDGYKPQQLSTYALTLFQYKTLVDGTDVRVDFWDTAGQERFSSMHPSYYHQAHSCLLVFDITRKVTYKNLAKWYKE 119 89********************************************************************************************** PP Ras 97 ikrvaeenvpivlvGnkvD 115 ++++ e n+p+++++nk+D FUN_001063-T1 120 LRDYRE-NIPCIVIANKID 137 ****99.6**********9 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.8 0.0 1.2e-11 3.1e-08 9 126 .. 17 137 .. 11 145 .. 0.81 Alignments for each domain: == domain 1 score: 33.8 bits; conditional E-value: 1.2e-11 Arf 9 klkkkelrilllGLDnaGKtTilkklkleelvt.....tiPTigfnvee.veiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRle 98 k+++++++++ lG + GK+ +++++ ++ + T f+ ++ v ++++ +wD Gqe+ ++ +Y+++ ++ + v D + + + FUN_001063-T1 17 KNTDRSVKVICLGDSAVGKSKLVERFLMDGYKPqqlstYALT-LFQYKTlVDGTDVRVDFWDTAGQERFSSMHPSYYHQAHSCLLVFDITRKVTYK 111 45689********99*********987765543211103333.466666256699***********************************999998 PP Arf 99 eakeeLkalleeeelkeaallvlaNKqD 126 + + k+l + ++++ +v+aNK+D FUN_001063-T1 112 NLAKWYKELRD--YRENIPCIVIANKID 137 88888888854..4568999*******9 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 0.0 9.3e-10 2.4e-06 1 113 [] 24 135 .. 24 135 .. 0.75 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 9.3e-10 MMR_HSR1 1 rvaivGrpNvGKStLinaltgk..kaivsdypgtTrdpnegklelkgkkielvDtpGliegaseee.gleraflaieeadlillvvd..aeeglte 91 +v+ +G + vGKS L+ + + + k + ++ T+ + + ++ ++ ++ ++Dt+G e ++ ++ ++ ++a+ +llv+d ++ ++++ FUN_001063-T1 24 KVICLGDSAVGKSKLVERFLMDgyKPQQLSTYALTLFQYKTLVDGTDVRVDFWDTAG-QE----RFsSMHPSYY--HQAHSCLLVFDitRKVTYKN 112 58899**************987667777777788888888889988899********.65....4546666666..36788888998653334555 PP MMR_HSR1 92 ldeeleellee.ekkpvilvlnk 113 l + +el + e++p+i+++nk FUN_001063-T1 113 LAKWYKELRDYrENIPCIVIANK 135 55544444333689********8 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.024 62 3 27 .. 22 46 .. 20 56 .. 0.83 2 ! 22.2 0.0 4.8e-08 0.00012 64 134 .. 66 139 .. 50 147 .. 0.81 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.024 GTP_EFTU 3 irnigiighvDhGKtTltdrllykt 27 + ++ +g+ GK+ l++r l++ FUN_001063-T1 22 SVKVICLGDSAVGKSKLVERFLMDG 46 5778899999**********99765 PP == domain 2 score: 22.2 bits; conditional E-value: 4.8e-08 GTP_EFTU 64 fetkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveGvepqteevlrl.ar..klgvpiivviNKmDrv 134 +++++ ++ + Dt G + F++ + q++ ++lv+d+++ v+ + + ++ +r ++++p iv+ NK+D + FUN_001063-T1 66 VDGTDVRVDFWDTAGQERFSSMHPSYYHQAHSCLLVFDITRKVTYKNLAKWYKeLRdyRENIPCIVIANKIDGI 139 4489999***********************************998888777651442246899*********76 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 7.2e-08 0.00018 1 124 [. 24 139 .. 24 144 .. 0.88 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 7.2e-08 Gtr1_RagA 1 kvLLmGksksGKsSi.rsviFsnyspkdtlrlgatidveksevrflgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedl 95 kv+ +G s GKs + ++ + + y+p++ + + t k+ v + ++ wd Gqe+f + +++ ++ + vfD++ + + FUN_001063-T1 24 KVICLGDSAVGKSKLvERFLMDGYKPQQLSTYALTLFQYKTLVD-GTDVRVDFWDTAGQERFSSMH-----PSYYHQAHSCLLVFDIT---RKVTY 110 79999********862789*****************99999995.7889***********998765.....667888899999*****...56677 PP Gtr1_RagA 96 arlketlealsevspeakvfvlihKvDli 124 ++l + ++l+++ +++ v+ +K+D+i FUN_001063-T1 111 KNLAKWYKELRDYRENIPCIVIANKIDGI 139 8888899999*****************98 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 1.7e-05 0.045 25 58 .. 12 45 .. 1 58 [. 0.76 2 ? -2.6 0.0 1.8 4.5e+03 53 68 .. 82 97 .. 80 114 .. 0.73 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.7e-05 TniB 25 alleapkkkrmpnlllvGdsnnGKstivekFarl 58 + e+ + +r +++ Gds++GKs++ve+F + FUN_001063-T1 12 ETGEKKNTDRSVKVICLGDSAVGKSKLVERFLMD 45 5556777888899999***************854 PP == domain 2 score: -2.6 bits; conditional E-value: 1.8 TniB 53 ekFarlhpaqkeedee 68 e+F+++hp ++++++ FUN_001063-T1 82 ERFSSMHPSYYHQAHS 97 6788888887776655 PP >> G-alpha G-protein alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 5.7e-05 0.15 14 62 .. 15 60 .. 2 126 .. 0.72 2 ? -1.0 0.0 0.42 1.1e+03 249 261 .. 125 137 .. 111 143 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 5.7e-05 G-alpha 14 ekkkakkevklLllGageSGKsTilkqmkilhkkgfseeerkeyraviy 62 ekk++ + vk+++lG + GKs +++ + +g++ +++++y + + FUN_001063-T1 15 EKKNTDRSVKVICLGDSAVGKSKLVERFL---MDGYKPQQLSTYALTLF 60 34444557**************9998887...78999999988655433 PP == domain 2 score: -1.0 bits; conditional E-value: 0.42 G-alpha 249 kntsiiLflNKiD 261 +n++ i++ NKiD FUN_001063-T1 125 ENIPCIVIANKID 137 7999********9 PP >> MMR_HSR1_Xtn C-terminal region of MMR_HSR1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 7.5e-05 0.19 37 72 .. 105 143 .. 90 149 .. 0.69 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 7.5e-05 MMR_HSR1_Xtn 37 redvtvddlidviegnrvY...ipclyvlNKiDlislee 72 +vt +l ++ r Y ipc+++ NKiD i l++ FUN_001063-T1 105 TRKVTYKNLAKWYKELRDYrenIPCIVIANKIDGILLKS 143 46777777776665555554449**********986665 PP >> AAA_7 P-loop containing dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00012 0.32 31 69 .. 20 59 .. 15 70 .. 0.84 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00012 AAA_7 31 knkkpvLlvGptGtGKtviikd.llkkldkekylsltinf 69 +++ +v++ G++ +GK+ ++++ l++ ++++++++ +++ FUN_001063-T1 20 DRSVKVICLGDSAVGKSKLVERfLMDGYKPQQLSTYALTL 59 567899****************999999999999888775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 765 (0.0299472); expected 510.9 (0.02) Passed bias filter: 652 (0.0255236); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1581.06 // Query: FUN_001064-T1 [L=778] Description: FUN_001064 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-29 102.4 0.5 1.4e-28 100.0 0.2 2.3 2 Transglut_N Transglutaminase family 2.1e-19 70.1 0.6 1.9e-11 44.5 0.1 2.7 3 Transglut_C Transglutaminase family, C-terminal ig like d 2.1e-11 44.5 0.1 5.8e-11 43.1 0.1 1.8 1 Transglut_core Transglutaminase-like superfamily ------ inclusion threshold ------ 0.021 15.3 0.0 0.042 14.4 0.0 1.5 1 2CSK_N Two-component sensor kinase N-terminal 0.084 13.9 1.9 0.17 12.9 0.5 2.3 2 Big_3_5 Bacterial Ig-like domain (group 3) 0.1 12.8 0.1 0.44 10.8 0.1 2.1 1 DUF7974 Family of unknown function (DUF7974) Domain annotation for each model (and alignments): >> Transglut_N Transglutaminase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.0 0.2 3.3e-32 1.4e-28 1 114 [] 94 209 .. 94 209 .. 0.96 2 ? -1.0 0.0 0.76 3.2e+03 26 85 .. 690 748 .. 680 763 .. 0.62 Alignments for each domain: == domain 1 score: 100.0 bits; conditional E-value: 3.3e-32 Transglut_N 1 ksvdlqkeeNnkeHhTdeys.skelvvRRGqpFkitlkfnrpfdpskdklslevetgpkpseskgtkavfpl.seeedeskWsakveesegnsltl 94 ++vd++++eN+++H+T+ y+ +++l++RRGq+F++t++fnr+++++ d++ l++ tg++p+eskg+ + + ++ d+++W +k+ + +g++++l FUN_001064-T1 94 EKVDFHIQENRNAHKTNSYEdENRLIIRRGQTFDVTVTFNRQYKSDLDTIVLQFVTGSRPQESKGSISRAVVqDNYLDPAHWGVKISKVSGKTIRL 189 589*****************899******************************************99999885667899***************** PP Transglut_N 95 svtspanapiGrYklsvevs 114 +++++a+a+iG Y+++ve++ FUN_001064-T1 190 TIMPSAKAIIGDYEVYVETK 209 *****************985 PP == domain 2 score: -1.0 bits; conditional E-value: 0.76 Transglut_N 26 vRRGqpFkitlkfnrpfdpskdklslevetgpkpseskgtkavfplseeedeskWsakve 85 v +G+ +it +f++p++ + ++++e +++ + +++ +++ +++e+k +++++ FUN_001064-T1 690 VKKGEDVEITASFKNPLSVPLTNGHFHFEATGMATKYEDVELTGSIA-SKKEAKATVSFT 748 67788888888888888888888888888554555555555555554.223333333333 PP >> Transglut_C Transglutaminase family, C-terminal ig like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 3.5 1.5e+04 14 33 .. 123 142 .. 121 151 .. 0.72 2 ! 44.5 0.1 4.5e-15 1.9e-11 2 106 .] 567 671 .. 566 671 .. 0.94 3 ! 23.4 0.0 1.7e-08 7e-05 10 103 .. 689 776 .. 679 778 .] 0.87 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 3.5 Transglut_C 14 gqdltvsvllkNplseelkd 33 gq ++v+v++ + ++ l + FUN_001064-T1 123 GQTFDVTVTFNRQYKSDLDT 142 79999999998666666655 PP == domain 2 score: 44.5 bits; conditional E-value: 4.5e-15 Transglut_C 2 elkievlesavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpskyGprkllve...lssdala 94 +++ev +++ +g ++v v+ N+++ +++k+n++ ++ +y+G++a+ k+k+++l+L+ +e++v lki + y +l+ +++ + a FUN_001064-T1 567 RFRFEVVDDISMGDNFEVKVVAENTSEFF-RTAKVNITSIMAFYTGIPAKPLKQKKETLRLGGMSEETVVLKIAAKDY--LGKLAGdgnIKLYVKA 659 689**********************9888.************************************************..666665599******* PP Transglut_C 95 kvkglkevlvaq 106 kv ++++ +v+q FUN_001064-T1 660 KVDETNQSYVKQ 671 *******99986 PP == domain 3 score: 23.4 bits; conditional E-value: 1.7e-08 Transglut_C 10 savvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpskyGprkllvelssdalakvkglkevl 103 + + g d+++++++kNpls +l++ + f e +G+ a++ + +l++++ k+e++ +++++ ++ + +++++ sd+la v+g +v+ FUN_001064-T1 689 AVKKGEDVEITASFKNPLSVPLTN-----GHFHFEATGM-ATKYEDVELTGSIASKKEAKATVSFTANRAQECTIVASFLSDQLAGVRGKCTVV 776 567799******************.....999*******.58****************************33444555*********9977665 PP >> Transglut_core Transglutaminase-like superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.1 0.1 1.4e-14 5.8e-11 49 107 .. 359 445 .. 337 446 .. 0.91 Alignments for each domain: == domain 1 score: 43.1 bits; conditional E-value: 1.4e-14 Transglut_core 49 tkkGncedfaslfvallRalGipaRlvtgylagede.....................vrsedaHawaevyl.......dgggWvpvD 107 k G+c+ f+ l+++llRalG+p+R vt++ +++d+ + +++H+w+e ++ +gW++ D FUN_001064-T1 359 VKYGQCWVFSGLVTTLLRALGLPTRSVTNFESAHDNdgsmtidfhfdeegnplhdlnDSVWNFHVWNESWFkrpdlpdGHDGWQAHD 445 467******************************999*********************99************9998876667798877 PP >> 2CSK_N Two-component sensor kinase N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 9.9e-06 0.042 43 84 .. 468 507 .. 461 554 .. 0.82 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 9.9e-06 2CSK_N 43 dgelevdlpyaalelleadaedrvyyqVldpdgellaGdadl 84 +g ev lpy + ++++ + drvy+qV d+dg ++a +++ FUN_001064-T1 468 EG--EVYLPYDTGFIFAEVNGDRVYWQVDDADGSMIAYNKET 507 34..7999***************************9988776 PP >> Big_3_5 Bacterial Ig-like domain (group 3) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 2.9 1.2e+04 11 36 .. 123 150 .. 121 163 .. 0.58 2 ? 12.9 0.5 4.1e-05 0.17 1 73 [. 683 765 .. 683 775 .. 0.79 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.9 Big_3_5 11 Gqsvtltatvtpasgs..ptGtVtftdg 36 Gq++ +t+t + + +s t +f+ g FUN_001064-T1 123 GQTFDVTVTFNRQYKSdlDTIVLQFVTG 150 5666666666655444344444455555 PP == domain 2 score: 12.9 bits; conditional E-value: 4.1e-05 Big_3_5 1 ltasptsvtyGqsvtltatvtpasgs..ptGtVtf.tdg.gtvlgtatlsan......GvatltvtaltaGthsitAtYsGda 73 +tasp++v+ G+ v++ta+ ++ + +G f g +t+ ++l+++ +at+++ta a + +i+A++ d+ FUN_001064-T1 683 VTASPKAVKKGEDVEITASFKNPLSVplTNGHFHFeATGmATKYEDVELTGSiaskkeAKATVSFTANRAQECTIVASFLSDQ 765 699******************644346788999998666667777666664344455599999999999*********98875 PP >> DUF7974 Family of unknown function (DUF7974) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.0001 0.44 14 45 .. 680 711 .. 672 714 .. 0.92 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0001 DUF7974 14 svsvetdreeyergepveltvtlrNrlPvpve 45 ++sv++ +++++ge+ve+t ++N l vp++ FUN_001064-T1 680 TISVTASPKAVKKGEDVEITASFKNPLSVPLT 711 6899999999*******************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (778 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 937 (0.0366804); expected 510.9 (0.02) Passed bias filter: 659 (0.0257976); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7264.07 // Query: FUN_001065-T1 [L=5064] Description: FUN_001065 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-08 33.0 151.6 1.6e-06 26.8 52.0 24.1 21 CCDC39 Coiled-coil domain-containing protein 39 9.6e-05 23.0 13.3 9.6e-05 23.0 13.3 40.9 37 HH_AprE AprE, long alpha-helical hairpin 0.00015 21.4 57.6 0.00042 20.0 18.2 31.4 31 Rod_CreS Crescentin, rod domain 0.0012 19.6 15.8 0.0012 19.6 15.8 45.3 43 ATG16 Autophagy protein 16 (ATG16) 0.0013 18.9 25.8 0.0013 18.9 25.8 36.9 37 FKBP15 FK506-binding protein 15-like domain 0.0014 19.2 8.6 0.0014 19.2 8.6 43.0 48 Laminin_II Laminin Domain II 0.0026 18.3 9.7 0.0026 18.3 9.7 48.0 45 ERM_helical Ezrin/radixin/moesin, alpha-helical domain ------ inclusion threshold ------ 0.14 13.0 0.1 1 10.2 0.1 2.6 1 TSCPD TSCPD domain 1.7 8.5 5.6 0.56 10.1 0.5 2.9 2 PRF Plethodontid receptivity factor PRF 7.5 6.4 6.1 73 3.2 0.6 4.1 2 Astro_p19 Astrovirus p19 protein Domain annotation for each model (and alignments): >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 1.3 0.12 3.1e+02 507 545 .. 40 78 .. 37 82 .. 0.90 2 ! 6.6 13.0 0.00081 2.1 733 830 .. 367 465 .. 359 469 .. 0.92 3 ? -11.6 62.1 10 2.6e+04 202 527 .. 455 776 .. 453 780 .. 0.88 4 ! 7.3 37.3 0.0005 1.3 241 447 .. 776 986 .. 772 992 .. 0.93 5 ! 17.4 23.1 4.4e-07 0.0011 228 381 .. 1005 1158 .. 995 1159 .. 0.96 6 ! 26.8 52.0 6.2e-10 1.6e-06 228 534 .. 1131 1436 .. 1123 1446 .. 0.91 7 ! 18.4 53.3 2.1e-07 0.00054 271 558 .. 1339 1625 .. 1330 1628 .. 0.96 8 ! 22.6 30.4 1.2e-08 3e-05 266 430 .. 1527 1694 .. 1519 1703 .. 0.91 9 ? 1.1 29.5 0.036 92 219 350 .. 1616 1754 .. 1612 1771 .. 0.53 10 ! 14.2 77.9 4e-06 0.01 154 533 .. 1712 2097 .. 1705 2097 .. 0.91 11 ! 13.2 70.6 8.2e-06 0.021 223 585 .. 1988 2354 .. 1986 2356 .. 0.94 12 ? -18.5 93.6 10 2.6e+04 255 625 .. 2274 2646 .. 2257 2649 .. 0.88 13 ? -2.1 91.1 0.35 8.9e+02 139 509 .. 2470 2832 .. 2470 2841 .. 0.93 14 ? -0.1 29.7 0.086 2.2e+02 309 522 .. 2906 3121 .. 2873 3168 .. 0.72 15 ? -20.1 71.4 10 2.6e+04 247 604 .. 3253 3609 .. 3233 3611 .. 0.75 16 ? -13.0 55.7 10 2.6e+04 217 520 .. 3602 3908 .. 3583 3910 .. 0.57 17 ? -2.9 28.2 0.59 1.5e+03 163 327 .. 3910 4079 .. 3901 4088 .. 0.76 18 ! 9.0 22.5 0.00015 0.39 225 379 .. 4029 4187 .. 4029 4200 .. 0.88 19 ? -1.1 23.2 0.17 4.3e+02 668 766 .. 4231 4337 .. 4226 4357 .. 0.68 20 ? -0.3 50.3 0.097 2.5e+02 153 494 .. 4353 4711 .. 4346 4715 .. 0.72 21 ? -15.1 47.7 10 2.6e+04 224 482 .. 4684 4945 .. 4680 4949 .. 0.61 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.12 CCDC39 507 lkeeleklkeklqelelenesgekelkklkkekeellVe 545 +++ l+ l e e++ne+ +e +kl ++kee lV+ FUN_001065-T1 40 DEDTIADLRRALSESEMRNEGINREFQKLLRQKEEELVQ 78 6677788999999*************************8 PP == domain 2 score: 6.6 bits; conditional E-value: 0.00081 CCDC39 733 leeleeeleeleqeleeleekeeelketleekeqeleklekeieeqkeKikRadkqlkklvkeirkkketkse.leekDielrelkevnklvlqqL 827 ++ lee+++e e+ +++l+ek++ l++ +k +e++ l+k i+++ + ik + +l+ + +ei ke+ ++ + ek+++l + n+ + ++ FUN_001065-T1 367 MALLEEKVKEREEMIRSLSEKMNFLEKGSVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKHETeMSEKEMKLSSQIKSNEELQKMV 462 66799**************************************************************9988779***********99999998887 PP CCDC39 828 ael 830 a+l FUN_001065-T1 463 ASL 465 765 PP == domain 3 score: -11.6 bits; conditional E-value: 10 CCDC39 202 haeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaeleneve 297 ++e q+++ ++++ +l+ +++ ++l +e +++ r++k++ ++++k l q + + ++k+ +l + r e + e+e+++l++++ FUN_001065-T1 455 NEELQKMVASLKDSLSELESKEKVTERLLLLDAEKEQQFRDEKQAFHDSEKALHGQLQVSLDHNSKM---SDELIEARAEIEAKEKEVKDLNSKIG 547 6677888888888888888888888888888888888888888888888888888887777766655...56899999999999999999999999 PP CCDC39 298 tlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqe 393 lk q + t l+n++ ++ ke++e e +l + +++ a+++k++++++++ ae + ele+ lee + ++ k+++ ++ +++ ++ FUN_001065-T1 548 KLKLQAKAKVTGLQNEKEKL---SKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQALEEFVRSTDKRGKHTSPGRKGSLEQDED 640 99988887777777776655...59999999***************************************************************** PP CCDC39 394 lkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkge..rseeekeelekkieeLeeeldekkktqnlLq 487 + + + + + i g+ ++ + + ++ le+e ++ l + + ++ ++kv++l++ +e+++++ ++i++ e+ k +++L FUN_001065-T1 641 EQVEELDGSGTVSTIVGSSTEETGFVNVMKILEEERYCMERRLDLITKERDSFKSKVEELEEMleAEKEQQQKKAEEISSDEDAEHAKHMAEESLM 736 *********************************************************999887656666666667778888887778888889999 PP CCDC39 488 sqikkleeelrklkkkleklkeeleklkeklqelelenes 527 +++ l+ee l+ +l+ +k+ l +lke+l++ +l e+ FUN_001065-T1 737 MHVEALQEENETLRVSLDLEKSALANLKEELKQAQLNQEN 776 9*********************************998876 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0005 CCDC39 241 rekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatd....lenqraeikelkkeieekekkle 332 +e ++e++ ++ l ++ke+ +l ++++ +++ +k ++ ++le el++ ++ vetl +ql++++++ le + ei++l+ + e+++ +e FUN_001065-T1 776 NELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQErnkvLEDKDKEISNLQGALMENSSGFE 871 67788999999****************************************************99988733335678999**************** PP CCDC39 333 klekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqe 428 l++++ + +l++++++ e+ ++ l+k + e+e +++l+ ++ + + + + l + ++ k +++ + a++++l++++++l +e FUN_001065-T1 872 VLNASFSESTIQLDRLQEQLAAKEAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNE 967 ************************************************************************************************ PP CCDC39 429 llkqqellynqefqiqqle 447 +++ ++++ + e +i l+ FUN_001065-T1 968 VQELRTVVDDKEAEIAHLK 986 *********9999998775 PP == domain 5 score: 17.4 bits; conditional E-value: 4.4e-07 CCDC39 228 klaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelk 321 +++ ++++l+e+++ k++el+ ++++++q + k+l + i+e +l+ l+e l e e+++l++++e + +l++lat+ e+ +++++el+ FUN_001065-T1 1005 ESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEESMTKVRELE 1098 567899**************************************************************************************** PP CCDC39 322 keieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeik 381 + ++k +l+++e le+ + e++++++ + e ++e+++ l+++e++ ++l+++++ FUN_001065-T1 1099 GNCASKDVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLN 1158 *****************************************************9998876 PP == domain 6 score: 26.8 bits; conditional E-value: 6.2e-10 CCDC39 228 klaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelk 321 +++ +++e++ + +k+e+ ++ +++l++ + ++l ++++ ++ kl +l++ l +e +++len ++ + k+ ++l+++l++++++i +k FUN_001065-T1 1131 ESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMK 1224 56778899999*********************************************************************************** PP CCDC39 322 keieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaai 415 ++i++k +++ l++k+ al+ +ee+k++ +a ++ +el +ll +e +l+ l++ ++ + ++ + + +l s+ ++l++ +s+ e +i FUN_001065-T1 1225 NDIANKDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQI 1318 ********************************************************************************************** PP CCDC39 416 knlkkkiakleqellkqqellynqefqiqqlerkvarlkge..rseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkklekl 507 ++l+ ++ q+++ + + + +l++ +a+ ++e +e +el + +eL+ +e +++ + Lq ++ e+el +lk +le+ FUN_001065-T1 1319 SSLERDVEATLQQYKDLE---SRHNSDVLKLKETIAEKESEnaSLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEK 1409 ***987766665555555...55667888888899888888767779999999***************************************** PP CCDC39 508 keeleklkeklqelelenesgekelkk 534 ++ l+++ + lq e e+ + + l+ FUN_001065-T1 1410 TACLKQMDDSLQRTETEVLRLQSILDE 1436 *********999998887666665555 PP == domain 7 score: 18.4 bits; conditional E-value: 2.1e-07 CCDC39 271 lerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakelek 364 + ++ kl+e+ +e e e a+l +ev+ l + s+l+t+ e+++a++k l++ +eke++l +l+++le+ + l++++++ +e + l+ FUN_001065-T1 1339 HNSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQS 1432 578999**************************************************************************************** PP CCDC39 365 lleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkge.. 456 +l+e+ l+e + +++ +++l + +++l + ++++ l+a+++ a ++l++++a++ + + + +e+l + + ++++l + + ++e FUN_001065-T1 1433 ILDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSL---SEEcf 1523 ************************************************************************************99...44557 PP CCDC39 457 rseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqelelenesgekelkklkkekeellVeenllr 550 + ++ el++k+ L+e+l+ek+++ + L+s++++ + + +l ++l ++ +le l+++l + +++ +k+ ++lkk++e+ + e+ ++ FUN_001065-T1 1524 YFDSRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYENAVSENENIQ 1617 89999*******************************************************************************9998888888 PP CCDC39 551 levkrlee 558 e+++l++ FUN_001065-T1 1618 KELDELRK 1625 88887776 PP == domain 8 score: 22.6 bits; conditional E-value: 1.2e-08 CCDC39 266 kkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeera 359 ++++el+ k+ l+e+l+e eee++ le+ ++ +++s+l+t l+ + ++++ l++++++k k+ +++kk +alk+ +e+ +++ ++++ + FUN_001065-T1 1527 SRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYENAVSENENIQKEL 1620 67899***************************************************************************************99 PP CCDC39 360 kelek...lleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqell 430 el k ++ ee+++ ++ +++ + k++l k++e++ l++k + + ++ + ++++ l +k+ +l+qel FUN_001065-T1 1621 DELRKereVFLEEKDAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELG 1694 9998622245566666677777777779999999**************************************85 PP == domain 9 score: 1.1 bits; conditional E-value: 0.036 CCDC39 219 lqqrdedIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrl...... 306 +q+ ++ +k e + e k ++++ ++l e+k+ l+ +e+ + lekk+ ++++l+ +e+++l +++ el++e+ +lk+q +rl FUN_001065-T1 1616 IQKELDELRKEREVFLEEKDAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLiderde 1709 4444455556666666666666666677777777777777777777777777777777777777777777777777777777766665111111 PP CCDC39 307 .atdlenqraeikelkkeieekekkleklekklealkekleevkn 350 ++l++++ae k+++ +++e ++k++++e ++++ + l+ +k+ FUN_001065-T1 1710 lHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKK 1754 133444444444444444444444444444444444444444433 PP == domain 10 score: 14.2 bits; conditional E-value: 4e-06 CCDC39 154 akikeLelereklseelnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqkla.eeieelkeeirekkee 246 +++++ e+e +++++ +ne ++k+++ e +++q Ld+ +e +e +L e++ +l+ +e+I+++a e+ e lk ei k++e FUN_001065-T1 1712 SQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLREATDL----REVIDHLKGVNEEISRAAaENAECLKTEILAKENE 1801 5678889999********************************************9....78************98761556679********** PP CCDC39 247 leeqkkflenqkennkelekkikelerklsklreelk....eleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklek 336 l++ ++ l++ +e+++k+ e e+ +kl+++ + + +++l+e e lkk ls+++++ + ++++ +k++++ +++le+ ++ FUN_001065-T1 1802 LHKVSQSLSSNMIMLEEIQAKLIESEKCSTKLKDDFElekdDWKTRLEEAACENSSLKKGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNN 1895 *********************************9765111155678889999999*************************************** PP CCDC39 337 klealkek...leevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleq 427 +l +l+++ l++v ++++ ++ ++l + +++++ + el+k++k+++ l k+ e+ el++ + + + ++ a ++i++l+ + + le+ FUN_001065-T1 1896 QLSTLQAEvshLQNVVKEEVLQSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEE 1989 ******86222566677899999*********************************************************************** PP CCDC39 428 ellkqqellynqefqiqqlerkvarlkgerseeekee..lekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklq 519 + k e n++ ++ ++ + ++r++ e++e e++ l++k+++ eld k+ + ++ i+ e+++ l+k+ ++l+++le+++ k q FUN_001065-T1 1990 SFGKAVEETSNLQANLSEMASELRRVSQEKTELESDVfdLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQ 2083 *****************************9998888622679***************9999999999999999999999999999999999999 PP CCDC39 520 elelenesgekelk 533 +l+ +e++ elk FUN_001065-T1 2084 QLHKDLEKTNDELK 2097 99888888777775 PP == domain 11 score: 13.2 bits; conditional E-value: 8.2e-06 CCDC39 223 dedIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqrae 316 +e++ k+ ee +l+++++e +el+ ++ + + + +l+ k+++++r+l ++e+l++++e +++ +++++ l k s l++ le+++ + FUN_001065-T1 1988 EESFGKAVEETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRK 2081 5788999*************************************************************************************** PP CCDC39 317 ikelkkeieekekkleklekklealkekleevknktlsaeerakelekl...leeeekrlkeldkeikklkealfkksqelkelkskektleae 407 ++l+k++e+ + +l+ + + ++ + klee++++ + +er+ +e++ l+e+e+ +l++e + lk++l +++ l+e+ ++++l+++ FUN_001065-T1 2082 EQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERLSAAEEVfskLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSN 2175 ***********************************************97333678888899********************************* PP CCDC39 408 isgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeel.dekkktqnlLqsqikkleeelrkl 500 + a ++++l ++ ++ ++el++ ++ l + e ++ l+++++ ++ + ++ + e i+ ++l + +++++ s k+ +++ +l FUN_001065-T1 2176 LVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSMEQRQGTHIPQVQEGFIAPGRNILlASVNEENSGFPSLEKQQVSQMEQL 2269 ***********************************************9999999999999998877765155555566666666777799**** PP CCDC39 501 kkkleklkeeleklkeklqelelenesgekelkklkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLeaamkeRk 585 + + ++l +el ++ +kl+e+ + + el +k++ ++l V++ + e++++++ + +++e+ +L +++l+ + + +eR+ FUN_001065-T1 2270 QLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEENSSKEERD 2354 ****************************************************************************999999997 PP == domain 12 score: -18.5 bits; conditional E-value: 10 CCDC39 255 enqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleev 348 +n ++ e+ k+ e +++ +el +++e+l++l + e + ++l+++++++++q+ e+++lk++ e+++ e+ k+ e+l + ee+ FUN_001065-T1 2274 DNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEENSSKEERDKSDERLLFRQEEL 2367 444455555555555555666666789999**************************************************************99 PP CCDC39 349 k.nktlsaeerakeleklleeeekrlkeld.keikklkealfkksqelkelkskektleaeisgaeaaik.nlkkkiakleqellkqqellynq 439 k +++ s + +k +e+l ++e ++ +++ k +k+l+++ +k + +lk+k + +++ a+ k +l + +++e+ l++ ++ l n+ FUN_001065-T1 2368 KlMQSYSEDVVTKRIEELTIAKELEKAQVEeKLTKQLQDTKTHKDGVIAKLKDKVREKIELNKKNIAEFKvKLANANKEKEETLQELHSQLANA 2461 85788889999******9888887777775166899******************988776666666666626677777777778899******* PP CCDC39 440 efqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqelelenesgekelk 533 e + + ++ ++ ++e++++l++ +L + ++ek++ + Lqsq++ + + +l+ +l++l++ ++ + ++l+ l+ + +e+e k FUN_001065-T1 2462 EKDKKAALEELKLFLDNSQKEKDQALQDLELQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGK 2555 ****999999999********************************************************************************* PP CCDC39 534 klkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLeaamkeRkaEIkvhkellraekrlleeersklkaelaerkakieqlkk 625 +++ +++e l + + l+le+++ e+ + + d+ ++ + + ++++ R++ I+ k+ l+ e+ + ++e +kl+ +ae+ a++eqlk+ FUN_001065-T1 2556 QKELKWQEALSDLQNLKLEIEKREQE-KVEMDTRLQTSVGQEEFDKSITDRNKLISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQLKA 2646 *********************97665.7888999999999***************************************************8 PP == domain 13 score: -2.1 bits; conditional E-value: 0.35 CCDC39 139 eednealekyskeDeakikeLelereklsee....lnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqk 228 ee ++ l++ +ke ++ +++Lel+ k +e ++e +++le + t++l +Ld+ ++ r +e + L ++ ++ ++ +q++ + q+ FUN_001065-T1 2470 EELKLFLDNSQKEKDQALQDLELQLAKAIAEkeevVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQE 2563 567788999999***********999986553344888999999999*********************************************** PP CCDC39 229 laeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkk 322 + ++++lk ei+++++e e + l++ + +e +k+i+ +++ +s l+++lk ee a ++e+ l+ ++ + + ++e+ +a+ + + FUN_001065-T1 2564 ALSDLQNLKLEIEKREQEKVEMDTRLQTSVGQ-EEFDKSITDRNKLISNLKKRLK---EERAAKKDELAKLQGSIAEKDANVEQLKAMHE---E 2650 ****************************9987.69***************98765...677899**********************9998...8 PP CCDC39 323 eieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaik 416 e+ e +k+++ l++++++lk+k e ++ + ae+ +l++ l+e k++k+l+++ ++lk++l +++ ++ s + l ++ ++a + + FUN_001065-T1 2651 ELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKRDLDEITKEKKDLERNHEQLKKEL---EEQETDFTSSVDALSSQRENADRKTE 2741 999999*********************************************************97...556678999***************** PP CCDC39 417 nlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklke 509 +l+ +++ l++e+ +++ nq+ + q l +v++l++ ++ +++ + i Le+el+ ++++ +L +q+++l eel lk ++++l++ FUN_001065-T1 2742 ELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQT--LKNKDQDIVRLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYDQLQA 2832 *************************************999553..5667789**********************************9999986 PP == domain 14 score: -0.1 bits; conditional E-value: 0.086 CCDC39 309 dlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskek 402 dl ++r+e+ke+++e+++ ++ ekl++k++ +k + +++ ++e+ +++ ++++ +++ +l+k +l+e+l ++ +e + k FUN_001065-T1 2906 DLHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSESVRDVES--SDMKAEIDKARQEKINLEKTALELREELVEIVREKDGTIGDLK 2997 7888889999999999888888888888888776666655555555554..3455667777777777777777788877777776665555555 PP CCDC39 403 tleaeisgaeaaiknlkkkiakleqell.kqqellynqefqiqqlerkvarlkgerseeekeelekk...ieeLeeeldekkktqnlLqsqikk 492 + ++ +++++ + l k +kl +e + + + + n++ + q l+ +++++ +++ k+ ++k ++eLe++ d +k + +++i + FUN_001065-T1 2998 QKIRQLLNEKSRNEVLVEKYEKLLAERDeEIKRIGANADVEAQGLRDRCQHVLEDKEFLVKKIQQEKleyVQELENTKDGYEKVLSDKDEEIGN 3091 5555555555555555555555555554233456799*****************9655555555555000556666666666666666799*** PP CCDC39 493 leeelrklkkkleklkeeleklkeklqele 522 ++ el ++ ++e+lk l++++e ++el+ FUN_001065-T1 3092 FKRELVSCNIETEELKGRLRQTQESFDELN 3121 ***********************9999885 PP == domain 15 score: -20.1 bits; conditional E-value: 10 CCDC39 247 leeqkkflenqkennkelekkike.lerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeiee....kekklekle 335 ++ l+n+ ++ +l++k+ke l++k sk r++ + e+ +e+ e+e+++ +++++++ r e+ ++ +e e+ ++k+e+l FUN_001065-T1 3253 TSDYVVSLQNELKQASDLNNKLKEaLKKKRSKPRSKSSGEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFVQEKERivagFKSKMEMLA 3346 5555567889999999999998863588889999999999999999999999999999999999999999999887775542222588999999 PP CCDC39 336 kklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqel 429 ++ e+++ +ee +++ l+ + ++ l ++ +++++l+ +++ l e ++ + +++++le +++ +++ k+ ++ +l++el FUN_001065-T1 3347 DEKERANSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVENLPELKLELQ----LTVQENAELENDLRYNKSLVKESTDRVSELKREL 3436 99999999999999999999999999998888888888888888888887766544....4444556666666666666666666666677777 PP CCDC39 430 lkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeel....dekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklq 519 + +e + +i++ +v +k + ++e el++ eL+++l d + +t++ L kle+ ++ + +e+ +++ ++l ++++ FUN_001065-T1 3437 ESREEKHLKEIEEIKERHDQVLIAKQKETDEAILELRQINTELQDNLqsvsDNRDATERELIGTRAKLEQVVQDSYPVIEEKSQKIQELLSQME 3530 6666666655556667777776666677777777777777777665511115667788888888899999999999999999999999999999 PP CCDC39 520 elelenesgekelkklkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLeaamkeRkaEIkvhkellraekrllee 604 e ++ ++ ++ e+ e ++e++++le++r e l + +++ ++ k++l+ + +++e + E+ +ke l+ ++++le FUN_001065-T1 3531 ENRINADNVI-----VQLERSESTLQEQVQELELSRTE-LKTQLEETRAEMRKQRLRFQRSVEEKETELREEKEGLQQQMQQLEA 3609 9999888877.....55567788888899999999865.5566677778999999999999999999999999999999988875 PP == domain 16 score: -13.0 bits; conditional E-value: 10 CCDC39 217 kqlqqrdedI....qklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrl 306 +q+qq ++++ ++++ +i +l+ee+ + + el ++ l+++ + +++ek ++ +s lr +l+++ ++ a e+ + + ql+++ FUN_001065-T1 3602 QQMQQLEAKFeellSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRNNFDHIISGLRGDLQQAINARAAAEELAHEFQVQLEKM 3695 3333333332000134455566666666666666666666666666666666666666666666666666666666655555555555555555 PP CCDC39 307 atdlenqraeikelkkeieek.ekkleklekklealkekleevknktlsaeerakeleklleeeekrlkel.dkeikklkealfkksqelkelk 398 + ++ +e+ e+ e+k ++ le+++ + ++l++ le + ++ r++ +e +l ++ +++ d + ++e + +k FUN_001065-T1 3696 RKSNPTTANEVDEISPPQENKvSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVLSTKSEKEALSsDDGNSNVNEDNVQKV------- 3782 555555555555555444444244555555555566666666666666666666666666544332222220222222333333322....... PP CCDC39 399 skektleaeisgaeaaiknl..................kkkiakleqellkqqellynq..efqiqqlerkvarlkgerseeekeelekkieeL 472 +++ + +i++l++el++ +++ ++ ++ ++ +r+v+ +g+ +++ ++el+ ++e++ FUN_001065-T1 3783 ----------------VEEVilqssednqvsslptsetEVEIENLKNELQRVKNVNEKLkaKLRTMMKKRRVKSDSGDEDSSVRNELQTELEKI 3860 ................222233334444444444433344555555555555555544400444566689999999999999999999999999 PP CCDC39 473 eeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqe 520 +e e++kt++ L +++ + e ++++l++ +el+ +ek ++ FUN_001065-T1 3861 RQEKLEREKTCQELRLELDTFVREKESITNELKRRIDELSAKNEKSNT 3908 999999999999999999999999999999999999999888887655 PP == domain 17 score: -2.9 bits; conditional E-value: 0.59 CCDC39 163 reklseelnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeirekkeeleeqkkflen 256 +e l++++++k +l + +++ +++++ d++ ++ l +e +L+ + e+ + q ++ ++d ++l +e+l ee ++ + + + + len FUN_001065-T1 3910 IEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLLAEKEDLISQSKEHEKDSSELKVYYESLVEEYNSLLDKKDRSIAHLEN 4003 8999********************************************************************9999988887777777777777 PP CCDC39 257 qkennke.....lekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieek 327 q ++ e l ++ ++ e + +++++ +le+e ++e e lk+ql++++++ e +++ + + FUN_001065-T1 4004 QLDEVTEkykteLRATRDQHEGIILQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHIVSNL 4079 7655332111003333334444456888888888888889999999999888888877766544444444444444 PP == domain 18 score: 9.0 bits; conditional E-value: 0.00015 CCDC39 225 dIqklaeeieelkeeirekkeeleeqkkflenqkennkelekk....ikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqr 314 +Iq+ a+++e+ + ++++ e+l+ q k ++n++e+ +l+++ ++ l ++l++ e ++ ++e +e++ +++ l k ++ t++en FUN_001065-T1 4029 QIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNfdhiVSNLREDLQRALEGKAAADEIAHEFQVQLKHLEKVSGNSGTQFENVA 4122 588999999999999999999999999999999999988877611114556666667777777899999************************* PP CCDC39 315 aeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldke 379 ++++ ++++ ee e+kl++++ + +++++ l+ k+++ +e + +le+ l+e e + ++ ke FUN_001065-T1 4123 VDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMKVNIGKE 4187 ********************************************************999988887 PP == domain 19 score: -1.1 bits; conditional E-value: 0.17 CCDC39 668 dakirkaEkEikaLenTLkvvnasNenyrksl.......skvdedseeleekkaLeeqlreaneklkekreeleeleeeleeleqe.leeleek 753 +++++k+ + +++n L+ v+a Ne+++++l + + +++e e++++L ++l +++++ e ++ ++l+ +l+e+ +e +++ e FUN_001065-T1 4231 NEEVQKVRDDWYKMQNELDKVKAVNERLKTKLktlmrkrKGGKVETSEEENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREkERRVVEH 4324 589*****************************66655543333344466777778888888888777777777777777776544424445555 PP CCDC39 754 eeelketleekeq 766 + ++++ l+eke+ FUN_001065-T1 4325 KTRMQQVLTEKEK 4337 5555555555554 PP == domain 20 score: -0.3 bits; conditional E-value: 0.097 CCDC39 153 eakikeLelereklseelnekkkklekevtetqslqieLdrta....eefrqlhaeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeire 242 +a i L +++ l ++l e +++l ++++e+++l ++L++ + + r+lha +L + e +l +++++I++l+ e+ +lke + FUN_001065-T1 4353 DAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNLNTVLEQLQlqkvKAERELHAATGELERLLEGDRPILAEKEQRISNLEAELSDLKESFDI 4446 566788999*******************************99733335667888888888888888888************************* PP CCDC39 243 kkeeleeqkkf.lenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenq...raeikelkkeieekekkle 332 ++++l+++ + ++q+++ ++le+++ +l+ + +l ++ k e ++++++ + +s l +dl + +a +e+ +e++ k +++e FUN_001065-T1 4447 EMRTLKDRYDVvVSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTNFDHIISGLREDLHGAlegKAAAEEIANELQMKFRRFE 4540 *****99998625788899999999999999999999999999999999999999999999999999998772224455555555555555555 PP CCDC39 333 klekkle........alkekle.evknktlsaeerakeleklleee...ekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaa 414 k + e +++ + +++++ ++e+ ++++ ee+ e++ +ldk +++ k l +k+++++ l+++ + l ae+ +++ + FUN_001065-T1 4541 KSSVSSElkvedvciGTEDMESrVLSDNEAEIEDLQTAVAQFREEKydlEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEHATSMEQ 4634 5444333333333332222211022233333333333333333322222555555666666666666666666666666666666666666666 PP CCDC39 415 iknlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkle 494 + +k k+ e+ k + n++ +++q + ++++k++++ ke+ kk+e+Le el ek++ + L+ +i +++ FUN_001065-T1 4635 LVLEVNKAGKERDEIRKE--MQINMDAAVMQSNKELDQMKEQYTL-LKENSAKKMEQLEGELSEKRQVIEKLSDEIGQFR 4711 666666666666666654..44799***************99875.4556669*******************99998876 PP == domain 21 score: -15.1 bits; conditional E-value: 10 CCDC39 224 edIqklaeeieelkeeirekkeeleeqkkflenqkennk...elekkikelerklsklreelkeleeelaelenevet.lkkqlsrlatdlenq 313 +++++l+ e+ e ++ i++ + e+ + ++ l n ++++k el+++ + le ++klr++l +++e+++l+ +++ ++l l+ ++e+ FUN_001065-T1 4684 KKMEQLEGELSEKRQVIEKLSDEIGQFRAGLVNKSDEEKlyeELQANYQLLETGNNKLRQDLYLTMKETENLRMKLKKdYDQMLASLKLEVEQS 4777 4455555566666666666666666666666555544432228889999999999999999999999999999998652566778888899999 PP CCDC39 314 raeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleae 407 r+++ e++k i++++ ++e l + e l +kl+e + t ++ +r+ ++ +e + ++e+ k++++ +k + + ++ ++ ++l+ e FUN_001065-T1 4778 RQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRTDGDAADDDEIVELKNEISLLRKECQDCRVEKDKLYDKFHDAVESLRKE 4871 9999999999999999999999999999999998888777777777665555555555555555555555555555555555555555555555 PP CCDC39 408 isgaeaaiknl.......kkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkkt 482 ++++ +++nl k+ ++l+q ll++q+ l ++ q + + + r e eke l+k++ee ++++ FUN_001065-T1 4872 LERSLHEKDNLaqkteetLKQNRELQQSLLEKQSALTKAKVQFEHIGKGW-RNDLEAARAEKELLQKQLEE-------RTSQ 4945 55555555555111111155555555555555555555555555554444.44444444555555555555.......4444 PP >> HH_AprE AprE, long alpha-helical hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.6 2.1 10 2.6e+04 141 177 .. 43 75 .. 40 85 .. 0.59 2 ? -11.5 26.1 10 2.6e+04 44 188 .. 161 311 .. 121 314 .. 0.64 3 ? 1.2 4.5 0.18 4.7e+02 64 126 .. 411 474 .. 398 481 .. 0.77 4 ? -1.6 19.6 1.4 3.5e+03 46 179 .. 488 614 .. 477 622 .. 0.71 5 ? -5.1 19.7 10 2.6e+04 47 174 .. 668 792 .. 659 807 .. 0.73 6 ? -8.1 21.3 10 2.6e+04 24 171 .. 741 838 .. 738 880 .. 0.56 7 ? 0.5 23.2 0.32 8.1e+02 3 176 .. 882 1078 .. 880 1084 .. 0.66 8 ? 0.3 17.5 0.35 8.8e+02 4 186 .. 967 1158 .. 966 1163 .. 0.77 9 ? 2.1 8.7 0.099 2.5e+02 63 166 .. 1137 1237 .. 1109 1268 .. 0.62 10 ? 1.0 16.4 0.22 5.6e+02 51 180 .. 1272 1401 .. 1249 1411 .. 0.77 11 ? -3.5 7.7 5.3 1.3e+04 116 189 .. 1394 1466 .. 1379 1468 .. 0.59 12 ! 23.0 13.3 3.8e-08 9.6e-05 53 186 .. 1467 1593 .. 1465 1598 .. 0.87 13 ? -4.9 19.8 10 2.6e+04 64 187 .. 1594 1716 .. 1591 1720 .. 0.79 14 ? -1.2 4.3 1 2.6e+03 120 185 .. 1713 1780 .. 1711 1851 .. 0.66 15 ? -3.8 18.6 6.6 1.7e+04 60 164 .. 1860 1964 .. 1836 1990 .. 0.52 16 ? 2.0 21.1 0.11 2.7e+02 54 190 .. 1997 2129 .. 1966 2130 .. 0.86 17 ! 5.6 4.8 0.0084 21 47 108 .. 2161 2222 .. 2138 2225 .. 0.85 18 ! 6.5 9.9 0.0045 12 82 169 .. 2262 2349 .. 2249 2369 .. 0.84 19 ? -1.5 1.4 1.3 3.2e+03 142 181 .. 2426 2468 .. 2418 2478 .. 0.48 20 ? -7.1 21.0 10 2.6e+04 63 165 .. 2485 2584 .. 2471 2595 .. 0.78 21 ? -1.7 24.9 1.5 3.8e+03 34 187 .. 2598 2756 .. 2585 2760 .. 0.84 22 ? -6.6 15.9 10 2.6e+04 52 113 .. 2765 2829 .. 2755 2834 .. 0.84 23 ? -0.0 7.7 0.44 1.1e+03 92 170 .. 2909 2989 .. 2901 3008 .. 0.82 24 ? -2.6 7.3 2.8 7.1e+03 21 164 .. 3019 3167 .. 3013 3173 .. 0.86 25 ? -3.2 6.3 4.3 1.1e+04 49 164 .. 3256 3371 .. 3235 3376 .. 0.80 26 ? -4.8 21.5 10 2.6e+04 51 190 .. 3397 3538 .. 3371 3539 .. 0.90 27 ! 6.6 19.1 0.0041 10 119 189 .. 3538 3608 .. 3536 3610 .. 0.96 28 ? -9.1 11.5 10 2.6e+04 69 112 .. 3615 3658 .. 3609 3738 .. 0.59 29 ? -3.7 12.2 6 1.5e+04 62 163 .. 3850 3952 .. 3845 3959 .. 0.90 30 ? -1.7 8.1 1.5 3.8e+03 6 115 .. 3939 4048 .. 3934 4070 .. 0.78 31 ! 5.5 3.5 0.009 23 55 108 .. 4125 4178 .. 4091 4181 .. 0.85 32 ? -4.0 7.8 7.4 1.9e+04 133 172 .. 4280 4319 .. 4275 4338 .. 0.71 33 ? 3.7 0.3 0.032 81 22 105 .. 4433 4516 .. 4422 4520 .. 0.66 34 ? -3.3 15.8 4.6 1.2e+04 80 187 .. 4569 4677 .. 4565 4685 .. 0.51 35 ? -0.1 9.0 0.46 1.2e+03 31 114 .. 4654 4737 .. 4648 4747 .. 0.75 36 ? -4.6 9.9 10 2.6e+04 63 181 .. 4761 4879 .. 4748 4889 .. 0.89 37 ? -1.7 6.5 1.4 3.6e+03 61 106 .. 4896 4941 .. 4879 4945 .. 0.82 Alignments for each domain: == domain 1 score: -4.6 bits; conditional E-value: 10 HH_AprE 141 eiararqqiaeaelqiaqlraeyreeaaeeLrevqae 177 ia +r++++e e + + +++e+++ + r+ ++e FUN_001065-T1 43 TIADLRRALSESEMRNEGINREFQKLL----RQKEEE 75 577777777777777777777776643....333333 PP == domain 2 score: -11.5 bits; conditional E-value: 10 HH_AprE 44 dpevaeliaaqrqlfearraalag...elailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqia 136 + ++ ++ +ql+e r ++++g +l+++++ ie+ ++ i++l+a+++ +l+ ++++++ ++ + + ++ +re+++l+ +++ FUN_001065-T1 161 AEGFQLKLEETKQLLEDRNKTVEGlmdRLDAQKRLIEGRDQVIDQLKAMKNLDSGADELVGTLREQIEAMNARVEKSVDEARRAKREISALKKELE 256 555555566778888888888776222455555668888888888888887766666666666666666666666677888889999999999887 PP HH_AprE 137 elraeia...rarqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraa 188 e + ia +++q+ + + +qi+++++e+++++ + + v+++ l + + a FUN_001065-T1 257 EKSELIAsaeKLEQEKSSLLIQIQEIEKEHKQTVLRLQHYVEEKEKALAAEFAEA 311 6655555111567888889999999999999999887777777666666666555 PP == domain 3 score: 1.2 bits; conditional E-value: 0.18 HH_AprE 64 alagelailqeqieqleeeieglraqlaalreqlal.leeelaglreLlekGlvpktrlleler 126 a+ +++lqe+++ ++ei+g++++ ++ ++ + l+ ++++++eL + k l ele FUN_001065-T1 411 DKASTIKVLQETLQAKDQEIAGIKEKHETEMSEKEMkLSSQIKSNEELQKMVASLKDSLSELES 474 5567889999999999999999999998877666544888999999998887777777777776 PP == domain 4 score: -1.6 bits; conditional E-value: 1.4 HH_AprE 46 evaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelrae 141 e +++ ++++q f+ +al g+l++ + ++ + e+ ++ra+++a++++++ l+ + +l+ l +k ++ l+ e l+ +++el+ FUN_001065-T1 488 EKEQQFRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEARAEIEAKEKEVKDLNSKIGKLK------LQAKAKVTGLQNEKEKLSKEMQELEMH 577 447999**************************************************9998886......444455555555555555555555555 PP HH_AprE 142 iararqqiaeaelqiaqlraeyreeaaeeLrevqaela 179 + r++ ++ +i q+++e +e a+++ e+++ l+ FUN_001065-T1 578 LLHEREEKLAIQKKISQIEEE-KEGAETKRTELEQALE 614 555555555555555555544.3444444444444444 PP == domain 5 score: -5.1 bits; conditional E-value: 10 HH_AprE 47 vaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraei 142 v ++++ +r +e r + + +e++ ++++e+lee +e+ ++q + + e+++ +e+ + + ++e+ l+ + +l+ e l+ +++ ++++ FUN_001065-T1 668 VMKILEEERYCMERRLDLITKERDSFKSKVEELEEMLEAEKEQQQKKAEEIS-SDEDAEHAKHMAEESLMMHVE--ALQEENETLRVSLDLEKSAL 760 5578888888888888888888888888888888888888888887777775.488888888888888887655..56666667777777778889 PP HH_AprE 143 ararqqiaeaelqiaqlraeyreeaaeeLrev 174 a +++++++a+l+ ++ ++ + +++ L+e FUN_001065-T1 761 ANLKEELKQAQLNQENELHSEMDSLRQVLAEE 792 99998888888877666555555555555554 PP == domain 6 score: -8.1 bits; conditional E-value: 10 HH_AprE 24 AErdgadtiefPaellaaa..a.dpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlv 116 A ++ ++t+++ +l+++a + +e++++ +q++ +++ ++l++ la +e+ l +++e +++ a + ++++ le+el+++r+ +e FUN_001065-T1 741 ALQEENETLRVSLDLEKSAlaNlKEELKQAQLNQENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVE---- 832 44444455555433333332234444445555555555555555555555555555555555555555555555555555555555555443.... PP HH_AprE 117 pktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeL 171 +++++L FUN_001065-T1 833 -------------------------------------------------TLERQL 838 .................................................333333 PP == domain 7 score: 0.5 bits; conditional E-value: 0.32 HH_AprE 3 aelealraqlaallaqeaRLqAErdgadt....ief.........P..aellaaaadpevaeliaa.......qrqlfearraalagelailqe 74 +l++l++qlaa +a+++RLq E++ +++ ++ + lla++ ++ ++ ++++ + + +++r+++l++e++ l++ FUN_001065-T1 882 IQLDRLQEQLAAKEAEVERLQKEMSEQEAgheqLKLsytgvcatvSemQLLLADK-EETLK-AVQThtdkqtaELNSLRSRHDELSNEVQELRT 973 589******************9999775555456664454444431333333333.22222.22222344444677788899999999999999 PP HH_AprE 75 qieqleeeieglraqlaalreqlalle....eelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyr 164 ++ e+ei+ l+a+ + ++ + + l+ e ++l++L e +++++l ++ + e +++ +l++ i++ +++ +++++ + ++e + FUN_001065-T1 974 VVDDKEAEIAHLKATTDEKDMSFEHLNtsliESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDE-V 1066 99999999999999888888877776622224456677777777778888888888888888888888888888888888888777766655.4 PP HH_AprE 165 eeaaeeLrevqa 176 +++ ++L+ +a FUN_001065-T1 1067 TDLTSKLENQEA 1078 455555555555 PP == domain 8 score: 0.3 bits; conditional E-value: 0.35 HH_AprE 4 elealraqlaallaqeaRLqAErdgadtief...Paellaaaa.dpevaeliaaqrqlfearraalagelai...lqeqieqleeeieglraql 90 e+++lr+ ++ +a+ a L A d + ++ f l ++++ ++++e+++a ++ +++ r++++++ + l++ i++ +++gl++ l FUN_001065-T1 967 EVQELRTVVDDKEAEIAHLKATTDEK-DMSFehlNTSLIESTSqLKDLEEIVQAKESELNSMRSNFDEQANSykdLTQVISENATRLQGLQEAL 1059 68999999****************55.6777545467777776689999*****9999999999999988872225688999999********* PP HH_AprE 91 aalreqlal....leeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelae 180 a++ ++ le + a+l++L+ + + t+++ele + a+ + ++ ++++++++ + + ++ a+ ++ ++e ++ L++ +++ + FUN_001065-T1 1060 VAKEDEVTDltskLENQEASLKDLATRCEESMTKVRELEGNCASKDVELKAMESALEERGLENERLNKSSAESER-SVNEMNDSLAKKEEKYNA 1152 ***999875111145566678899999999999999999999999999999999998765555544444444333.367888888888888888 PP HH_AprE 181 leerlr 186 l+ +l+ FUN_001065-T1 1153 LQANLN 1158 887776 PP == domain 9 score: 2.1 bits; conditional E-value: 0.099 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqi 156 ++++ +la +e+ l++ +++ +a+++ l + + ++ l++l++Ll +++ + le +l e+e + ++l++e+++a+ i +++ i FUN_001065-T1 1137 NEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLL---IAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMKNDI 1227 4555556666666666666666666666666666666666666666665...555555566666666666666666666666666666666666 PP HH_AprE 157 aqlraeyree 166 a+ ++e ++ FUN_001065-T1 1228 ANKDEEIVTL 1237 6666555443 PP == domain 10 score: 1.0 bits; conditional E-value: 0.22 HH_AprE 51 iaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlek.Glvpktrllelerelaelegqiaelraeia 143 +++ +++++ ++ ++ ++l++++++ ++++++l +l++++ q+++le++++++ + ++ ++++l l+ ++ae e++ a+l +e++ FUN_001065-T1 1272 KETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLERDVEATLQQYKDlESRHNSDVLKLKETIAEKESENASLCSEVK 1365 45588899999999999*************************************98766555415556789**********************9 PP HH_AprE 144 rarqqiaeaelqiaqlraeyreeaaeeLrevqaelae 180 ++ + +e++ + ++++a+ ++ +++ +e + el e FUN_001065-T1 1366 ELVFRASELNTRNEEANAS-LKALQDVFNEKENELFE 1401 9999999999888777654.34455555555555555 PP == domain 11 score: -3.5 bits; conditional E-value: 5.3 HH_AprE 116 vpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraar 189 ++++l el+ +l e + + +++ +++r++ ++ +++ +++ + + +ee + +e + +l+el+erlr+ + FUN_001065-T1 1394 EKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSILDE-KLADLEESRMGFAENSNQLNELRERLRNKE 1466 4556666666666666666666666666666666665543333.334455666667777888888888887765 PP == domain 12 score: 23.0 bits; conditional E-value: 3.8e-08 HH_AprE 53 aqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiarar 146 +++l++a+ +++++ +++l++++++ ++ ++l+++l+a+++++++l+ +L e+ ++ +r+ el+ ++ +l+ q+ae + ei+ ++ FUN_001065-T1 1467 EESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNM------SLSEECFYFDSRVSELQDKVGALQEQLAEKEEEIQALE 1554 57788888888888888888888888888888888888888888888874......799*********************************** PP HH_AprE 147 qqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlr 186 +++ e + i +l+++ +++++++L++++++la+ + + FUN_001065-T1 1555 SSLDERSQSISNLDTS-LTDTSTQLEDLRSQLASKDGKFA 1593 ************9876.79*************98776665 PP == domain 13 score: -4.9 bits; conditional E-value: 10 HH_AprE 64 alagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqia 157 a++++ ++l+++ e + +e e+++++l+ lr++++ + ee +++++ l + + k++l + e+ le +++ ++ +++ + ++ + + ++++ FUN_001065-T1 1594 AMKKKAQALKKSYENAVSENENIQKELDELRKEREVFLEEKDAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVI 1687 78899999**************************************************************999999988888888888777777 PP HH_AprE 158 qlraeyreeaaeeLrevqaelaeleerlra 187 +l++e + e+ + + e +el +l++ FUN_001065-T1 1688 ELQQEL-GLLKEQTQRLIDERDELHSQLNQ 1716 777663.34444444444444444444443 PP == domain 14 score: -1.2 bits; conditional E-value: 1 HH_AprE 120 rllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreea..aeeLrevqaelaeleerl 185 +l + e e ++e +++e + ++++++ +++e+++ ++ l++e ++ a++Lrev l ++e++ FUN_001065-T1 1713 QLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLreATDLREVIDHLKGVNEEI 1780 45555555555555555555555555555555555555544443332211344555555555444444 PP == domain 15 score: -3.8 bits; conditional E-value: 6.6 HH_AprE 60 arraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeae 153 + +++ ++++ l++q+ ++ ++ +++l+ ++ ql+ l++e++ l+ +++ + ++ l e+ + + +i el+ ++++ + +++ e FUN_001065-T1 1860 KGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHLQNVVKEEVLQSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKE 1953 4445555555555555555555555555555555555555555555555555555555555555555555555555555555555555555555 PP HH_AprE 154 lqiaqlraeyr 164 ++++l++ + FUN_001065-T1 1954 GEVTELNNLSL 1964 55555444333 PP == domain 16 score: 2.0 bits; conditional E-value: 0.11 HH_AprE 54 qrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpkt.rllelerelaelegqiaelraeiarar 146 +++ ++a+ +++a+el ++ ++le+ + l+ +l++++++l+ ++e+l++ +G++ ++ ++ le++++ le++++e++ + ++++ FUN_001065-T1 1997 ETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLTNAS----EGITTRNeQIKSLEKDRSHLESSLEEMQRKEQQLH 2086 6777899999*****************************************9965....6666666155689********************** PP HH_AprE 147 qqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraard 190 + +++++ +++ ++ +e +++L+e+++e +e +erl aa++ FUN_001065-T1 2087 KDLEKTNDELKYM-DDLCKERESKLEELNKEREEDKERLSAAEE 2129 ***9999998766.5678888999***************99986 PP == domain 17 score: 5.6 bits; conditional E-value: 0.0084 HH_AprE 47 vaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglr 108 v + i+++++ ++++ a ++l+ l+++ eq+++e+e+l+++l+ +++++ ll+ +++++ FUN_001065-T1 2161 VLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSME 2222 4456777899999999999999*********************************9999987 PP == domain 18 score: 6.5 bits; conditional E-value: 0.0045 HH_AprE 82 eieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaae 169 +++++++ ++ +a l e +++l e e lv t+ll+ + +l +l+ q + +++e++ ++q+ +e e ++a+l+++++ee ++ FUN_001065-T1 2262 QVSQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEENSS 2349 44444444444445556688999***********************************************************998664 PP == domain 19 score: -1.5 bits; conditional E-value: 1.3 HH_AprE 142 iararqqiaeaelqiaqlra...eyreeaaeeLrevqaelael 181 i+ ++ iae++ ++a++++ e ++e+ ++L+ ++++ + FUN_001065-T1 2426 IELNKKNIAEFKVKLANANKekeETLQELHSQLANAEKDKKAA 2468 4445555555555555544300033344444444444433333 PP == domain 20 score: -7.1 bits; conditional E-value: 10 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqi 156 +al+ +l + i++ ee +++l++ql+ + + + l++ l +L +++ v +l l+r+l ++e++ + + + ++a + ++ ++l+i FUN_001065-T1 2485 QALQDLELQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAA---LDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEI 2575 34444444566677777777777777777666666666554...456678999***************************************** PP HH_AprE 157 aqlraeyre 165 +++++e +e FUN_001065-T1 2576 EKREQEKVE 2584 ***999765 PP == domain 21 score: -1.7 bits; conditional E-value: 1.5 HH_AprE 34 fPaellaaaa.dpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGl.vpktrllele 125 f + ++ +++ ++++ ++ +r+ + a+l+g++a ++++eql++ e+ ++ + + l+ ++ l+++re le+ +++ +++ l+ FUN_001065-T1 2598 FDKSITDRNKlISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMsIAEDEMINLK 2691 56666677766777788899999999999999999999999999999999999999999999999999999999999999876489999***** PP HH_AprE 126 relaelegqiaelraeiararqqiaeaelqiaq...lraeyreeaaeeLrevqaelaeleerlra 187 r+l e+ + +l+ + ++++++++e e + + ++ re+a+++ +e+q +l+ l+e++ FUN_001065-T1 2692 RDLDEITKEKKDLERNHEQLKKELEEQETDFTSsvdALSSQRENADRKTEELQLQLDALNEEVSE 2756 **************************999877611155678999999999999999999998765 PP == domain 22 score: -6.6 bits; conditional E-value: 10 HH_AprE 52 aaqrqlfearraalagelailq...eqieqleeeieglraqlaalreqlalleeelaglreLlek 113 + ++ql+ + ++l++ ++ l+ + i +le+e++ ++++ l eql +l+eel l++ +++ FUN_001065-T1 2765 QEEKQLLVDQVQQLSEAVQTLKnkdQDIVRLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYDQ 2829 458889999999999999999622267999**************************999887765 PP == domain 23 score: -0.0 bits; conditional E-value: 0.44 HH_AprE 92 alreqlalleeelaglreLlekGlvpktrllelerelaelegqi..aelraeiararqqiaeaelqiaqlraeyreeaaee 170 +r +l+ +++el++ ++L ek ++ + er+ +e ++ ++++aei +arq+ +e +lr+e +e ++e+ FUN_001065-T1 2909 KTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSESVRDVesSDMKAEIDKARQEKINLEKTALELREELVEIVREK 2989 5677888899**************************9998655411789***********999999999999988877765 PP == domain 24 score: -2.6 bits; conditional E-value: 2.8 HH_AprE 21 RLqAErdga.dtiefPaellaaaadpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlek 113 L+AErd + + i a+++a+ + + + ++++ + l ++ +++ + ++ l+++ ++ e+ ++ ++++ + +++l + + e + l++ l + FUN_001065-T1 3019 KLLAERDEEiKRIGANADVEAQGLRDRCQHVLEDKEFLVKKIQQEKLEYVQELENTKDGYEKVLSDKDEEIGNFKRELVSCNIETEELKGRLRQ 3112 69999997766688899998777799999*************************************************9999999999999999 PP HH_AprE 114 Glvpktrllelere....laelegqiaelraeiararqqiaeaelqiaqlraeyr 164 + +l l+ + ++ l+g+++++ e a a q e++ q+++ +++y FUN_001065-T1 3113 TQESFDELNKLKVDfdhiISGLRGDLQQALEEKAVADQLAHEFRVQLERMKSSYA 3167 9999999988876522226789999999999999999999999999999888876 PP == domain 25 score: -3.2 bits; conditional E-value: 4.3 HH_AprE 49 eliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraei 142 +++ q++l +a + + + a+ +++ + ++ +++ ++ e + ++ +++ ++++ l + + e er +a +++++ l e FUN_001065-T1 3256 YVVSLQNELKQASDLNNKLKEALKKKRSKPRSKSSGEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFVQEKERIVAGFKSKMEMLADEK 3349 67777888888887777777777777777778888888888888888888888899999999999999999999999999999*********** PP HH_AprE 143 ararqqiaeaelqiaqlraeyr 164 +ra++ i+e+e q+ +++ r FUN_001065-T1 3350 ERANSLIEEYEKQLLTKDTAVR 3371 ********99999998877765 PP == domain 26 score: -4.8 bits; conditional E-value: 10 HH_AprE 51 iaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelagl..reLlekGlvpktrllelerelaelegqiaelraei 142 ++ + ql + a+l+++l ++ +++ + ++++l+++l++ +e ee++ + L +k+ +lel++ +el+ ++++ + + FUN_001065-T1 3397 LKLELQLTVQENAELENDLRYNKSLVKESTDRVSELKRELESREEKHLKEIEEIKERhdQVLIAKQKETDEAILELRQINTELQDNLQSVSDNR 3490 5668899999999******************************999988888888762256********************************* PP HH_AprE 143 ararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraard 190 +++++ ++++++q+ ++ ++e+ +++q+ l+++ee++++a++ FUN_001065-T1 3491 DATERELIGTRAKLEQVVQDSYPVIEEKSQKIQELLSQMEENRINADN 3538 *****************************************9998875 PP == domain 27 score: 6.6 bits; conditional E-value: 0.0041 HH_AprE 119 trllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraar 189 + +++ler+ + l+ q++el+ + ++++ q++e+++++ + r +++ ++e+ e+++e + l++++++++ FUN_001065-T1 3538 NVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRFQRSVEEKETELREEKEGLQQQMQQLE 3608 6789***************************************************************9986 PP == domain 28 score: -9.1 bits; conditional E-value: 10 HH_AprE 69 lailqeqieqleeeieglraqlaalreqlalleeelaglreLle 112 l++ q++i++leee++ + +l + +e l+ ++ e +++++L + FUN_001065-T1 3615 LSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRN 3658 56667777777777777777777777777777777777766654 PP == domain 29 score: -3.7 bits; conditional E-value: 6 HH_AprE 62 raalagelailqeqieqleeeieglraqlaalreqlalleeela.glreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeael 154 r++l++el+ ++++ + e+ ++lr +l++ ++ +++ el+ ++ eL +k+ ++t + +le ++ + +gq+ el ++ +++ +a + FUN_001065-T1 3850 RNELQTELEKIRQEKLEREKTCQELRLELDTFVREKESITNELKrRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQ 3943 899************************************999973589*****************************99999999999999988 PP HH_AprE 155 qiaqlraey 163 +++ lr+e FUN_001065-T1 3944 NVETLRHEN 3952 888888876 PP == domain 30 score: -1.7 bits; conditional E-value: 1.5 HH_AprE 6 ealraqlaallaqeaRLqAErdgadtiefPaellaaa.a.dpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreql 97 +++++ + +l+ + a L+AE +++ i +e ++++ + ++ l++ ++l++++ +++a ++l+e e+ + e+++ r q ++ q+ FUN_001065-T1 3939 DQAWQNVETLRHENADLLAEKEDL--ISQSKEHEKDSsElKVYYESLVEEYNSLLDKKDRSIAHLENQLDEVTEKYKTELRATRDQHEGIILQI 4030 677888888888888899998855..55555555555134555669999999999999999999999999999999999999999999999999 PP HH_AprE 98 alleeelaglreLlekGl 115 ++ ++ l++ r L+ k FUN_001065-T1 4031 QSHADNLEKERLLASKET 4048 999999999988888765 PP == domain 31 score: 5.5 bits; conditional E-value: 0.009 HH_AprE 55 rqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglr 108 ++ e+r ++l+++l++ q++++ ++ ++ +++ +++l+ ++a+le+el + FUN_001065-T1 4125 TSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERE 4178 555799*******************************************98766 PP == domain 32 score: -4.0 bits; conditional E-value: 7.4 HH_AprE 133 gqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLr 172 +++el +e+a++rq+ e+e + +qlr + e ++e+ r FUN_001065-T1 4280 ENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREKER 4319 5677888888888888888888888888777666666544 PP == domain 33 score: 3.7 bits; conditional E-value: 0.032 HH_AprE 22 LqAErdgadt.iefPaellaaaadpevaeliaaqrq...lfearraalagelailqeqieqleeeieglraqlaalreqlalleeela 105 L+AE++++++ ++ l+++ + +++ q++ +e+ +l++e ++l+++++ +e ie +++ +++ + ++ l+e+l FUN_001065-T1 4433 LEAELSDLKEsFDIEMRTLKDR----YDVVVSEQQKhinNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTNFDHIISGLREDLH 4516 8888888855355543333333....34444444431115788888899999999999999999999888888888887777777776 PP == domain 34 score: -3.3 bits; conditional E-value: 4.6 HH_AprE 80 eeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqq....iaeaelqiaqlraeyreeaae 169 e+eie l+ +a re+ lee++ +l + ++ G k +l+e + ++ le +i++l ae a + +q +++a + +++r+e++ + ++ FUN_001065-T1 4569 EAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDG---KGDLMEKQEQIQTLEEDIERLAAEHATSMEQlvleVNKAGKERDEIRKEMQINMDA 4659 55666666666666666666666666666666665...44555555555555555555555444433331111345555555555555555555 PP HH_AprE 170 eLrevqaelaeleerlra 187 + ++el++++e+++ FUN_001065-T1 4660 AVMQSNKELDQMKEQYTL 4677 555555555555555543 PP == domain 35 score: -0.1 bits; conditional E-value: 0.46 HH_AprE 31 tiefPaellaaaa.dpevaeliaaqrqlf....earraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekG 114 +i+ a ++++++ ++++ q +l+ +++ ++l+gel+ ++ ie+l+ ei + ra l ++ + +l eel+++ +Lle G FUN_001065-T1 4654 QINMDAAVMQSNKeL----DQMKEQYTLLkensAKKMEQLEGELSEKRQVIEKLSDEIGQFRAGLVNKSDEEKLY-EELQANYQLLETG 4737 566666666666422....5555555555111156889*********************************9998.5788888888887 PP == domain 36 score: -4.6 bits; conditional E-value: 10 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqla.lleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelq 155 + +++ la l+ ++eq +++ + ++ + ++r +++ l+++ + + +L e G v + l + ++a+ + +i el+ ei+ +r++ ++ + + FUN_001065-T1 4761 KDYDQMLASLKLEVEQSRQQNLEKEKFIHNQRIEVEsLVRDKESLITKLRETGQVTRETLQRTDGDAAD-DDEIVELKNEISLLRKECQDCRVE 4853 6788999999999******999999999999977752678888889**********************9.789********************* PP HH_AprE 156 iaqlraeyreeaaeeLrevqaelael 181 +++l ++++ +++ +e+++ l e FUN_001065-T1 4854 KDKLYDKFHDAVESLRKELERSLHEK 4879 ******************99999875 PP == domain 37 score: -1.7 bits; conditional E-value: 1.4 HH_AprE 61 rraalagelailqeqieqleeeieglraqlaalreqlalleeelag 106 +++l +++++l++ q+e +g r l+a+r++ +ll+++l+ FUN_001065-T1 4896 LQQSLLEKQSALTKAKVQFEHIGKGWRNDLEAARAEKELLQKQLEE 4941 37899999999********************************985 PP >> Rod_CreS Crescentin, rod domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 31.2 0.59 1.5e+03 7 229 .. 43 276 .. 38 281 .. 0.79 2 ? -4.0 25.3 3.2 8.2e+03 17 139 .. 222 342 .. 214 358 .. 0.72 3 ? -11.5 34.3 10 2.6e+04 23 245 .. 280 509 .. 278 513 .. 0.80 4 ? -22.2 47.3 10 2.6e+04 23 268 .. 491 750 .. 488 753 .. 0.55 5 ! 8.2 39.3 0.00059 1.5 4 190 .. 756 954 .. 753 955 .. 0.86 6 ! 16.9 28.1 1.4e-06 0.0036 10 180 .. 942 1112 .. 924 1114 .. 0.83 7 ! 20.0 18.2 1.6e-07 0.00042 5 133 .. 1105 1233 .. 1101 1241 .. 0.94 8 ! 7.9 10.0 0.00074 1.9 88 191 .. 1230 1333 .. 1223 1342 .. 0.68 9 ! 18.9 31.4 3.5e-07 0.0009 5 171 .. 1340 1506 .. 1337 1511 .. 0.91 10 ! 15.1 24.5 5e-06 0.013 91 243 .. 1507 1665 .. 1501 1682 .. 0.74 11 ? -1.3 16.1 0.48 1.2e+03 14 134 .. 1671 1787 .. 1668 1790 .. 0.79 12 ? -1.6 31.3 0.6 1.5e+03 19 220 .. 1785 1989 .. 1773 1993 .. 0.77 13 ? -5.5 38.9 9.3 2.4e+04 15 190 .. 1949 2124 .. 1928 2129 .. 0.67 14 ? -1.5 30.3 0.53 1.4e+03 27 175 .. 2073 2224 .. 2070 2228 .. 0.81 15 ? -12.5 29.3 10 2.6e+04 34 208 .. 2264 2440 .. 2244 2444 .. 0.71 16 ? -11.5 34.1 10 2.6e+04 5 132 .. 2408 2542 .. 2378 2553 .. 0.59 17 ? -7.1 33.6 10 2.6e+04 8 196 .. 2505 2689 .. 2504 2692 .. 0.75 18 ? -3.1 35.4 1.7 4.3e+03 7 137 .. 2686 2816 .. 2680 2848 .. 0.80 19 ? -9.6 26.8 10 2.6e+04 1 193 [. 2907 3113 .. 2907 3166 .. 0.75 20 ? -7.8 27.2 10 2.6e+04 11 195 .. 3260 3448 .. 3246 3451 .. 0.59 21 ? -17.2 54.5 10 2.6e+04 4 221 .. 3425 3656 .. 3422 3693 .. 0.69 22 ? -10.6 41.8 10 2.6e+04 15 208 .. 3540 3749 .. 3533 3759 .. 0.64 23 ? -18.7 30.5 10 2.6e+04 9 195 .. 3686 3879 .. 3677 3887 .. 0.74 24 ! 5.0 25.3 0.0057 14 3 174 .. 3859 4024 .. 3857 4034 .. 0.88 25 ? -0.0 8.0 0.19 5e+02 75 174 .. 4031 4130 .. 4028 4131 .. 0.92 26 ? 3.6 7.2 0.016 40 6 65 .. 4123 4182 .. 4118 4193 .. 0.89 27 ? -4.3 21.9 4 1e+04 7 128 .. 4247 4364 .. 4241 4369 .. 0.87 28 ! 4.5 27.7 0.0082 21 5 181 .. 4318 4499 .. 4315 4508 .. 0.80 29 ? 1.2 25.4 0.083 2.1e+02 24 211 .. 4510 4703 .. 4494 4705 .. 0.87 30 ? -11.6 21.2 10 2.6e+04 13 169 .. 4670 4823 .. 4656 4828 .. 0.72 31 ? -5.1 21.8 6.8 1.7e+04 27 162 .. 4831 4960 .. 4821 4985 .. 0.68 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.59 Rod_CreS 7 rllelealleqetaasdklrrevagltrrlsaaereleelsa.....rlakleaalkeaea...akeelrielrektalaealErqlkaeteqnra 94 +++l++ l++ ++ ++re ++l+r+ + +l e + ++ +++++a+ + + +++ l++k + +lE+ql + + + r FUN_001065-T1 43 TIADLRRALSESEMRNEGINREFQKLLRQKEEELVQLRENVRagpslSPSEFPSEVQDANNpvqDIQHIQVLLAQKDEVIGDLEKQLHESEAHVRR 138 577888888888888888888888888887766655555443111113456678888888611144567899************************ PP Rod_CreS 95 leeelkaLrae.akaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearla..eletaldaerarlralegqLaaeqaererae 187 le++ +++ ++ + ++ +aeg +++e ++lle+ n+ l++ a+ e r + + +a+++ + ++l g L ++ ++ ++ + FUN_001065-T1 139 LEQQGCDNEEKvMHELAVKIRAAEGFQLKLEETKQLLEDRNKTVEGLMDRLDAQKRLIEGRDQviDQLKAMKNLDSGADELVGTLREQIEAMNARV 234 **99776666615667899******************************998876666666661155556666778889999******99999999 PP Rod_CreS 188 aqleeevealraEraslamklealsaRaaateqlltqaRnqL 229 +++ +e+ +++ E+++l+ +le+ s a++e+l ++ L FUN_001065-T1 235 EKSVDEARRAKREISALKKELEEKSELIASAEKLEQEKSSLL 276 9999*****************************999877666 PP == domain 2 score: -4.0 bits; conditional E-value: 3.2 Rod_CreS 17 qetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnra.leeelkaLraeakaaek 111 + +++ +++++ v++ +++ +a+re+++l ++l++ ++ + +ae+ +e + l +++++E++ k+ + ++ +ee kaL ae++ ae+ FUN_001065-T1 222 TLREQIEAMNARVEKSVDEARRAKREISALKKELEEKSELIASAEKLEQEKSSLL----IQIQEIEKEHKQTVLRLQHyVEEKEKALAAEFAEAEQ 313 4455555666666666666666666666666666666666666666555555444....46899*********999984777789*********** PP Rod_CreS 112 alqeaegelat.arerlalleqEnrrLqa 139 e++l++ + e+ +++e +++q FUN_001065-T1 314 VYKTNEHDLRErLDEKAQIIESKDEAIQV 342 *******9875268888999988777775 PP == domain 3 score: -11.5 bits; conditional E-value: 10 Rod_CreS 23 dklrrevagltrrlsaaerelee.lsarlakleaalkeaeaakeel...rielrektalaealErqlkaeteqnraleeelkaLraeakaaekalq 114 +++ +e++++ rl +e+e+ l+a+ a++e+ k +e + e+ ++++ e + +a ++ +++ +e++ + + + ++ ++ ++ e+++ FUN_001065-T1 280 QEIEKEHKQTVLRLQHYVEEKEKaLAAEFAEAEQVYKTNEHDLRERldeKAQIIESKDEAIQVLKRAIQEKNLSSEGSSPPSHSDKVMALLEEKVK 375 566778888888887766665551455566666555555554433211133444444444445555555655555666666788999999****** PP Rod_CreS 115 eaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaqleeevealraEraslamklea 210 e e+++++++e+ + le+ + + ++ + + +++ + l ++l+a+ + ++ + + e +e+e + + + +++e l+ asl+ l++ FUN_001065-T1 376 EREEMIRSLSEKMNFLEKGSVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKHETEMSEKEMKLSSQIKSNEELQKMVASLKDSLSE 471 ************************************************************************************************ PP Rod_CreS 211 lsaRaaateqll...tqaRnqLrerdeairaaEralke 245 l+ + te+ll ++ +q r+ +a++ +E+al + FUN_001065-T1 472 LESKEKVTERLLlldAEKEQQFRDEKQAFHDSEKALHG 509 **********9955568889999999*******99865 PP == domain 4 score: -22.2 bits; conditional E-value: 10 Rod_CreS 23 dklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkae...........teqnraleeelkaLraeak 107 ++ r+e ++ + a+ ++l+ ++ ++ k++++l ea+a+ e+ e+++ ++++ +l q+ka +++ ++le l + r+e FUN_001065-T1 491 QQFRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEARAEIEAKEKEVKDLNSKIGKLKLQAKAKvtglqnekeklSKEMQELEMHLLHEREEKL 586 555666666666666666666666666666666666666666666666666666666555555554111100000003334444444444555555 PP Rod_CreS 108 aaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegq.LaaeqaereraeaqleeevealraEra 202 a k++++ e+e + a+ ++ leq + + + +++ + + + r le+ d++ + l +g +++ e + ++ l+ Er FUN_001065-T1 587 AIQKKISQIEEEKEGAETKRTELEQALEEFVRSTDKRGKHTSP--GRKGSLEQDEDEQVEEL---DGSgTVSTIVGSSTEETGFVNVMKILEEERY 677 5555555555555555555555555555555555555444432..34555555555555554...4331233333333334444445555666666 PP Rod_CreS 203 slamkle.......alsaRaaateqlltqaRnqLrerdeairaaEralkeasieratlerrlegleadlarqt 268 ++ +l+ + + + +e +l ++q++ ++e+i + E a ++ ++l+ +e+l+++++ ++ FUN_001065-T1 678 CMERRLDlitkerdSFKSKVEELEEMLEAEKEQQQKKAEEISSDEDAEHAKHMAEESLMMHVEALQEENETLR 750 6666664111111155677888999**********************9999*****************99876 PP == domain 5 score: 8.2 bits; conditional E-value: 0.00059 Rod_CreS 4 akvrllelealleqet.aasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 +k++l++l++ l+q + +++++l e+++l++ l++ +++ +l ++l+ ++++ ++ +++e l el++k++++e+lErql++ t+++ ++ e+ FUN_001065-T1 756 EKSALANLKEELKQAQlNQENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQERNKVLED 851 6899999999999876256789***************************************************************99887777665 PP Rod_CreS 99 lk........aL...raeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaer 183 ++ aL ++ +++ +++ +e+ +l++++e+la e+E +rLq+ + eq a +l+ + +++ + + l++ e L a q+ + FUN_001065-T1 852 KDkeisnlqgALmenSSGFEVLNASFSESTIQLDRLQEQLAAKEAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHT 947 5412221111222223456788999*********************************************9999999999999******9999999 PP Rod_CreS 184 eraeaql 190 ++ a+l FUN_001065-T1 948 DKQTAEL 954 9998875 PP == domain 6 score: 16.9 bits; conditional E-value: 1.4e-06 Rod_CreS 10 elealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLr 103 +++ + ta+ ++lr +++l++++ ++ +++ a++a+l+a e++ +e l +l e t+++++lE +a + + +++++ + FUN_001065-T1 942 AVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDDKEAEIAHLKATTDEKDMSFEHLNTSLIESTSQLKDLEEIVQAKESELNSMRSNFDEQA 1035 4677778888899999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP Rod_CreS 104 aeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeq 180 + k + ++e l+ ++e+l e+E + L + e+q a l +l+ r +e t++++ ++ +++L a++ FUN_001065-T1 1036 NSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEESMTKVRELEGNCASKDVELKAME 1112 99999999999999999999999999999999999999999999999999999988888887777777777776665 PP == domain 7 score: 20.0 bits; conditional E-value: 1.6e-07 Rod_CreS 5 kvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 v+l +e+ le+ +++ l+++ a+ +r ++++++ l++ ++ ++l+a+l+e++a+ e+l ++ + + a++ +l++ l a +e ++le+ FUN_001065-T1 1105 DVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENT 1198 578888999************************************************************************************* PP Rod_CreS 99 lkaLraeakaaekalqeaegelatarerlalleqE 133 lk ++ ++ e++l ea+g+++ +++ a ++E FUN_001065-T1 1199 LKEIEKSHQQLESELNEANGNIDGMKNDIANKDEE 1233 **********************9998887766666 PP == domain 8 score: 7.9 bits; conditional E-value: 0.00074 Rod_CreS 88 eteqnraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqa 181 +e++ +l+e + aL + ++ +ea ++++++++ l l e E + L+ ve+q+ +l++rla +++l++ +l++ e q+++ + FUN_001065-T1 1230 KDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLER 1323 5666777777777777777777777777777777777777777777777777777777777777777777777777777777777777776665 PP Rod_CreS 182 ereraeaqle 191 e+ +q++ FUN_001065-T1 1324 DVEATLQQYK 1333 5555555554 PP == domain 9 score: 18.9 bits; conditional E-value: 3.5e-07 Rod_CreS 5 kvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 ++ +l l++ ++ ++++l ev++l r+s+++ + ee+ a l++l++ +e+e + el+++l+ekta +++++ l+ + + l++ FUN_001065-T1 1340 NSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSI 1433 567889999999*********************************************************************9888888778877 PP Rod_CreS 99 lkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlra 171 l+ + a ++ + +e ++l+++rerl e+E++ L+a vee a + +le+rlae++ + + +++l+a FUN_001065-T1 1434 LDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSA 1506 7777777777777789999*****************************************9999888877765 PP == domain 10 score: 15.1 bits; conditional E-value: 5e-06 Rod_CreS 91 qnraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaere 184 +n+++ + + L++e +++++e++ + ++e+la e+E ++L + +e + +++l+ l +++t+l++ r++l++ +g++aa++ +++ FUN_001065-T1 1507 KNKEVDSLNMSLSEECFYFDSRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQ 1600 5677777777888888888888888888888888888888888888888888888888888888888888888888888888888888888888 PP Rod_CreS 185 raeaqlee...evealraEraslamklealsaRaaateqlltqa...RnqLrerdeairaaEral 243 + ++ +e+ e+e + E l+ + e a+e+ ltq+ +nqL+ ++e+++ E++l FUN_001065-T1 1601 ALKKSYENavsENENIQKELDELRKEREVFLEEKDAMEKCLTQLiehKNQLQAKNEEVQGLEKKL 1665 88888887222345567788888888888888888888887764333777888888888877776 PP == domain 11 score: -1.3 bits; conditional E-value: 0.48 Rod_CreS 14 lleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraeak 107 +l+ ++++++l ++v +l+++l+ ++++ ++l + ++l ++l+++ea+k+++ ++++e + ++ ++E + ++ + +l++el+ + ea FUN_001065-T1 1671 SLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLREA- 1763 566667778888888889999999999999999999999999999999999999999999999999999888888888888888877666554. PP Rod_CreS 108 aaekalqeaegelatarerlalleqEn 134 ++l e++ +l+ ++e+ ++++En FUN_001065-T1 1764 ---TDLREVIDHLKGVNEEISRAAAEN 1787 ...467788888888888888777777 PP == domain 12 score: -1.6 bits; conditional E-value: 0.6 Rod_CreS 19 taasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelr....ielrektalaealErqlkaeteqnraleeelkaLraeaka 108 ++++ l++e+ + +++l ++++ l+ + l++++a+l e e+ + +l+ +e ++ ++++e++ + ++ +++e ++ L +++++ FUN_001065-T1 1785 AENAECLKTEILAKENELHKVSQSLSSNMIMLEEIQAKLIESEKCSTKLKddfeLEKDDWKTRLEEAACENSSLKKGLSEMTEKQDSLTTQLNV 1878 4566779999999999**************************99887776332256667777777777777777788889999*********** PP Rod_CreS 109 aekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaererae.aqleeevealraEr 201 + k+l ++++el+ ++++l l++E Lq++v e + + + e +e a++ + +l++qL ++q + +e + e ++ +l+ + FUN_001065-T1 1879 SQKDLKRSQEELEMKNNQLSTLQAEVSHLQNVVKEEVLQSQKGETLTDE----IHAKKLEILELQKQLKQQQHLLNDKEgEVTELNNLSLENKK 1968 ***********************************99997766554444....45556666678888887777644444044455555555555 PP Rod_CreS 202 a..slamklealsaRaaateq 220 a ++ ++e+ls R +a+e FUN_001065-T1 1969 AlnFANTRIEELSERGNALEE 1989 422578899999999999885 PP == domain 13 score: -5.5 bits; conditional E-value: 9.3 Rod_CreS 15 leqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraeaka 108 l+ + +l++ + +++l+ a+ ++eels+r ++le++ +a +++++l+++l+e ++++++ ++ + + l+ l+ + e+ a FUN_001065-T1 1949 LNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDA 2042 3333334445555555556777778888888888888888888888888888888888888888888777777777777788888888888888 PP Rod_CreS 109 aekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaql 190 ++l++a + ++t +e+ + le++ L + ee + +l l+ + l+ ++ e++L + + ere ++ l FUN_001065-T1 2043 IKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERL 2124 8888888888888888888888888888888888887777777777777777777777777777777777777776655544 PP == domain 14 score: -1.5 bits; conditional E-value: 0.53 Rod_CreS 27 revagltrrlsaaereleelsarlakleaalkeaeaakeelrielr...ektalaealErqlkaeteqnraleeelkaLraeakaaekalqeae 117 ++++++r+ ++ ++le++ +l+ +++ ke+e + eel e + e+ ++ae++ +l++ + al++e++ L++e++ ++ lqe FUN_001065-T1 2073 SSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREedkERLSAAEEVFSKLQEMESFYGALKQEKESLKTELEDVNNVLQEIT 2166 5677888888888888999999999999999999988888755544000445555556567777777788999999999999999999999999 PP Rod_CreS 118 gelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegq 175 e +++ +l + + + L + e++ ael +l+ l++ et + ++r++++e++ FUN_001065-T1 2167 TEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSMEQR 2224 9999999999999999999999999999999999999999999999999999999986 PP == domain 15 score: -12.5 bits; conditional E-value: 10 Rod_CreS 34 rrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraeakaaekalqe...aegelatar 124 +++ +++ e+++l+a+l++ ++l+e + k el + + ++++l q + t + +++++e + ++e++ ++ e + +e+++ FUN_001065-T1 2264 SQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEensSKEERDKSD 2357 4556677788889999999999999888888888899999999999999999999999999999888888887766555433132667788888 PP Rod_CreS 125 erlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaqleeevealraEraslamkl 208 erl ++E + +q+ +e+++ + e ++ele+a +e + +++l+ ++ ++ + + e++e + +a + kl FUN_001065-T1 2358 ERLLFRQEELKLMQSYSEDVVTKRIEELTIAKELEKAQVEE-KLTKQLQDTKTHKDGVIAKLKDKVREKIELNKKNIAEFKVKL 2440 88888888888889999998877666666677887765443.334455555566666666666666666666666666666666 PP == domain 16 score: -11.5 bits; conditional E-value: 10 Rod_CreS 5 kvrllelealleqetaasdklr.revagltrrlsaaereleelsarla.kleaalkeaeaakeelrielr....ektalaealErqlkaeteqn 92 k + ++ a+l+ + ++ +l+ +++a+ + +l++a++e+ee++++l+ +l++a k++ aa eel++ l+ ek +++++lE ql+++ ++ FUN_001065-T1 2408 KTHKDGVIAKLKDKVREKIELNkKNIAEFKVKLANANKEKEETLQELHsQLANAEKDKKAALEELKLFLDnsqkEKDQALQDLELQLAKAIAEK 2501 4444444455555555555543145666666777777777766666652455555666666677766553222255666667777776666555 PP Rod_CreS 93 raleeel.kaLraeakaaekalqeaegelatarerlalleq 132 +++ +el ++L+ + +++e+ +++++ ++++r + le FUN_001065-T1 2502 EEVVQELqSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEG 2542 55555531456666666666666666666666555444444 PP == domain 17 score: -7.1 bits; conditional E-value: 10 Rod_CreS 8 llelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelka 101 ++el++ le ++ ++l + +++l+++ +ele l +l ++e++ k++e + +e+ ++l++ ++++e+ E++ + + + ++ ++ + FUN_001065-T1 2505 VQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEMDTRLQTSVGQ-EE 2597 5788999999999999999999999999988999999999999999999999999999988888888888888877766666666554333.33 PP Rod_CreS 102 LraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaqleeeve 195 ++ + +k ++++ + ++e++a ++E +Lq + e a++ +l+a ++e + ++ ++l++ ++ L +++++ er ++ +e+e+ FUN_001065-T1 2598 FDKSITDRNKLISNLKKR---LKEERAAKKDELAKLQGSIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMI 2688 444555555555555544...4566677788888888888888888888888888888888888888888888888888888888888888876 PP Rod_CreS 196 a 196 FUN_001065-T1 2689 N 2689 5 PP == domain 18 score: -3.1 bits; conditional E-value: 1.7 Rod_CreS 7 rllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelk 100 ++++l++ l ++t++++ l r++++l+++l + e +++ + +++l+++ ++a++++eel+++l+ + ++ + r+ +++e+++ l +++ FUN_001065-T1 2686 EMINLKRDLDEITKEKKDLERNHEQLKKELEEQETDFT---SSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQ 2776 789*************************9998888776...5578999999******************************************* PP Rod_CreS 101 aLrae...akaaekalqeaegelatare.rlalleqEnrrL 137 +L++ +k +++++ ++e+el+ +e +l+l+eq + L FUN_001065-T1 2777 QLSEAvqtLKNKDQDIVRLENELQLSQEeKLQLAEQ-LTSL 2816 **9761115679***********9666515666665.4444 PP == domain 19 score: -9.6 bits; conditional E-value: 10 Rod_CreS 1 lpkakvrllelealleqetaasdklrrevagltrr...lsaaerel..eelsarlakleaalkeaeaakeelriel....rektalaealE... 82 l k++++l e++a l++ a ++kl+++v+ ++ s++ r++ ++ a+++k+ ++ + e+++ elr el rek + +l FUN_001065-T1 2907 LHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKeraKSESVRDVesSDMKAEIDKARQEKINLEKTALELREELveivREKDGTIGDLKqki 3000 578999*********************9997654411144444444114567788888888888888888888776444477888888776555 PP Rod_CreS 83 rqlkaeteqnraleeelkaLraeakaaekal.qeaegelatarerla.lleqEnrrLqalveeqaaelaelearlaeletaldaerarlraleg 174 rql +e+ +n+ l e ++L ae + k++ ++a+ e + +r+r + +le+ + +++ e + ele + + e+ l ++ + + + FUN_001065-T1 3001 RQLLNEKSRNEVLVEKYEKLLAERDEEIKRIgANADVEAQGLRDRCQhVLEDKEFLVKKIQQEKLEYVQELENTKDGYEKVLSDKDEEIGNFKR 3094 89999*******999999988888877777746688888888888651556666666888888999999************************* PP Rod_CreS 175 qLaaeqaereraeaqleee 193 +L++ + e+e + l + FUN_001065-T1 3095 ELVSCNIETEELKGRLRQT 3113 ***9998888776655444 PP == domain 20 score: -7.8 bits; conditional E-value: 10 Rod_CreS 11 lealleqetaasdklrrevaglt.rrlsaaereleelsarlakleaalkeaeaakeelrielr.ektalaealErqlkaeteqnraleeelkaL 102 l++ l+q + ++kl++ +++ + + +s++++e e + + +a+le ++ a +++++ ++lr e +++ Er + + + + l+ e+++ FUN_001065-T1 3260 LQNELKQASDLNNKLKEALKKKRsKPRSKSSGEHEMSNETIAELE-VIRAAKVESDKQMAHLRlELDNFVQEKERIVAGFKSKMEMLADEKERA 3352 344444444444444444433321335677777766666666555.244444444444444443334455666666666677788888999999 PP Rod_CreS 103 raeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelear...laeletaldaerarlralegqLaaeqaereraeaqleee 193 + + +ek+l + + ++++ + +ll En +L++ ve+ el+ + +aele+ l+ +++ +++ + ++ + e e e+++ +e FUN_001065-T1 3353 NSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVENLPELKLELQLTvqeNAELENDLRYNKSLVKESTDRVSELKRELESREEKHLKE 3446 9999999999999999999999999999999999998888665544444444000555666666666666666666666666666555555555 PP Rod_CreS 194 ve 195 +e FUN_001065-T1 3447 IE 3448 54 PP == domain 21 score: -17.2 bits; conditional E-value: 10 Rod_CreS 4 akvrllelealleqetaasdklrrevagltrr.lsaaereleelsarlakleaalkeaeaakeelr.ielrektalaealErqlkae....teq 91 + r++el++ le +++ k +e+++ ++ l a ++e +e+ +l++++++l+++ + ++ r +++re +++lE+ ++ +e+ FUN_001065-T1 3425 STDRVSELKRELESREEKHLKEIEEIKERHDQvLIAKQKETDEAILELRQINTELQDNLQSVSDNRdATERELIGTRAKLEQVVQDSypviEEK 3518 5668888988888877777776667666665524556677788888888777777776555544442455555555555555444432222677 PP Rod_CreS 92 nraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelear....laeletaldae....rarlralegqLa 177 +++++e l+++++ a++ + ++e+ t++e+ + le + L+ ee ae+ + r ++e et l++e ++++++le+++ FUN_001065-T1 3519 SQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRfqrsVEEKETELREEkeglQQQMQQLEAKFE 3612 8888888888888888888888888888888888888888889999999999999987754441111566666665542222789999999999 PP Rod_CreS 178 aeqaereraeaqleeevealraEraslamklealsaRaaateql 221 + ++ +++ ++leee++ E s ++kl ++ + + e+l FUN_001065-T1 3613 ELLSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKL 3656 99999999999999999999999999999999999877777766 PP == domain 22 score: -10.6 bits; conditional E-value: 10 Rod_CreS 15 leqetaasdklrrevagltrrlsaaereleelsarlak....leaalkeaeaakeelrielrektalaea.lErqlkaeteqnraleeelkaLr 103 q ++ +l+++v++l+ + +++ +lee+ a+++k ++++++e+e++ e + l+++ +++ea E l + + + +leeel++ FUN_001065-T1 3540 IVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKqrlrFQRSVEEKETELREEKEGLQQQMQQLEAkFEELLSQSQASISKLEEELAHTN 3633 5555666667777777777777777777776666655322226788888888888888888888877775367777777778888888888888 PP Rod_CreS 104 aeakaaekalqeaegelatarerl....alleqEnrrLqalveeqaa......el.aelearlaeletaldaerarlralegqLaaeqaerera 186 e+ + +++lq a+ge ++ ++ + +++ Lq++++ aa e ++le + + t++++ + + +e + +++ ++++r FUN_001065-T1 3634 MELVSFNEKLQTADGEKQDIEKLRnnfdHIISGLRGDLQQAINARAAaeelahEFqVQLEKMRKSNPTTANEVDEISPPQENKVSEMLEATQRE 3727 8888888888888877666544431111344444445555544433211000033123333333444444444444556799************ PP Rod_CreS 187 eaqleeevealraEraslamkl 208 ea+l +++ea Er +l+ +l FUN_001065-T1 3728 EANLRAALEATLIERDALQNRL 3749 ******************9998 PP == domain 23 score: -18.7 bits; conditional E-value: 10 Rod_CreS 9 lelealleqetaasdklrrevagltr.rlsaaereleelsarlakleaalkeaeaakeelrielrektalae.alErqlkaeteqnraleeelk 100 e + le+ ++++ + +ev++++ + +++++ le+++ + a+l aal+ + + ++l+ +lr+ ++ + + E+++ ++ n +++e++ FUN_001065-T1 3686 HEFQVQLEKMRKSNPTTANEVDEISPpQENKVSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVLStKSEKEALSSDDGNSNVNEDNV 3779 5888999999*************99636677777777777888899999999999999999999999887652689999999999999999987 PP Rod_CreS 101 aLrae..akaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLa...aeqaereraeaq 189 ++ e ++ ++ q + + + + + l++E +r +++ e+ a+l + + + + d++++ ++l+++L +e+ ere+ ++ FUN_001065-T1 3780 QKVVEevILQSSEDNQVSSLPTSETEVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDSGDEDSSVRNELQTELEkirQEKLEREKTCQE 3873 6655411333344444444444555556677999**************9999988888888888887777778887775111566666666666 PP Rod_CreS 190 leeeve 195 l e+ FUN_001065-T1 3874 LRLELD 3879 665555 PP == domain 24 score: 5.0 bits; conditional E-value: 0.0057 Rod_CreS 3 kakvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnrale 96 k + ++le e+ ++ + + d+ re +++t ++++r+++elsa+++k+++ +++ ea++++ +l e ++ +E +++ ++ ++l+ FUN_001065-T1 3859 KIRQEKLEREKTCQELRLELDTFVREKESIT---NELKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLR 3949 5566677777777777777777777777776...67899******************************************************* PP Rod_CreS 97 eelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlraleg 174 e++ L ae +e ++++ ++ ++ +e + +e + ++l ++ +a+le +l+e ++ ++e++++r++ FUN_001065-T1 3950 HENADLLAE---KEDLISQSKEHEKDSSELKVYYESLVEEYNSLLDKKDRSIAHLENQLDEVTEKYKTELRATRDQHE 4024 *****9665...78999999999999999999*********************************9999999987644 PP == domain 25 score: -0.0 bits; conditional E-value: 0.19 Rod_CreS 75 talaealErqlkaeteqnraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerar 168 +++a +lE++ +++++++l+++lk ++e + k + ++ ++re+l+++ + + + +++ e+ ++l +le + + t+ ++ FUN_001065-T1 4031 QSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHIVSNLREDLQRALEGKAAADEIAHEFQVQLKHLEKVSGNSGTQFENVAVD 4124 6899*************************************************************************99998888888877777 PP Rod_CreS 169 lraleg 174 ++++e+ FUN_001065-T1 4125 TSDIET 4130 777665 PP == domain 26 score: 3.6 bits; conditional E-value: 0.016 Rod_CreS 6 vrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaake 65 v +++e+ e+ ++ d++++e+a+++++l ++++++l +++a+le++l+e+e+ k FUN_001065-T1 4123 VDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMKV 4182 6678899999999******************************************99775 PP == domain 27 score: -4.3 bits; conditional E-value: 4 Rod_CreS 7 rllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelk 100 +l ++a++e+ + ++l r+ +g + + s+ e++ eel +lak+ ++ e+e+a+++lri+l+e +++ Er+ + + + +++ e++ FUN_001065-T1 4247 ELDKVKAVNERLKTKLKTLMRKRKGGKVETSEEENR-EELHTELAKVRQEKLETERAAQQLRIDLDE---IVREKERRVVEHKTRMQQVLTEKE 4336 556678888888888888888888888888886665.8899999999999999**********9998...578889****************** PP Rod_CreS 101 aLraeakaaekalqeaegelatarerla 128 + + ++++ek l e ++++ ++ e+ + FUN_001065-T1 4337 KVNNLLETKEKLLLERDAAISSLVEQIQ 4364 ********************99999876 PP == domain 28 score: 4.5 bits; conditional E-value: 0.0082 Rod_CreS 5 kvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 + r++e ++ ++q +++k+++ ++ ++ l + + ++ l+++++ l ++l+e e+ +++ +e r+ ++ +e+l+ q +++++ a ++e FUN_001065-T1 4318 ERRVVEHKTRMQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNLNTVLEQLQLQKVKAERELHAATGE 4411 5689999999999999999999999988888888888888888888888888888888888888888888888888887777777777777777 PP Rod_CreS 99 lkaL....raeakaaekalqeaegelatarerlalle.qEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqa 181 l++L r ++ +e++++++e+el +++e ++ + r +v eq ++++le++l l t ++ +r++a e + + + FUN_001065-T1 4412 LERLlegdRPILAEKEQRISNLEAELSDLKESFDIEMrTLKDRYDVVVSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINK 4499 777744445568899*****************99843033456666777999**************************9987766555 PP == domain 29 score: 1.2 bits; conditional E-value: 0.083 Rod_CreS 24 klrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektal.aealErqlkaeteqnraleeelkaLraeakaaekalqea 116 lr+++ g ++ +aae+ +el+ + +++e++ + e ++e i ++ +++ + + E++ ++ + +++ee+ L++++ a +k +q+ FUN_001065-T1 4510 GLREDLHGALEGKAAAEEIANELQMKFRRFEKSSVSSELKVEDVCIGTEDMESRvLSDNEAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDG 4603 599*****************************************99999887762578999999999999999999999999999999999999 PP Rod_CreS 117 egelatarerlalleqEnrrLqa....lveeqaaelaelearlaeletaldae.rarlralegqLaaeqaereraeaqleeevealraErasla 205 g+l +++e+ + le++ +rL a +e+ + e+++ + +e + ++ + a++ + +++L +++++ + ++++ +++e+l+ E + + FUN_001065-T1 4604 KGDLMEKQEQIQTLEEDIERLAAehatSMEQLVLEVNKAGKERDEIRKEMQINmDAAVMQSNKELDQMKEQYTLLKENSAKKMEQLEGELSEKR 4697 99999999999999999999976333369**************999888875515778899999999999999999999999999999998877 PP Rod_CreS 206 mkleal 211 +e l FUN_001065-T1 4698 QVIEKL 4703 777766 PP == domain 30 score: -11.6 bits; conditional E-value: 10 Rod_CreS 13 alleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraea 106 ++ eq t +++ +++++l+ +ls+ + +e+ls +++++ a l ++ ++e ++ +e +a+ + lE++ ++ ++ +e + Lr ++ FUN_001065-T1 4670 QMKEQYTLLKENSAKKMEQLEGELSEKRQVIEKLSDEIGQFRAGLVNK---SDEEKL-YEELQANYQLLETGNNKLRQDLYLTMKETENLRMKL 4759 333333333333334566777788888888888888888888887765...344444.4678888899999999999999999999999**999 PP Rod_CreS 107 ka.aekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarl 169 k +++ l+ + e ++ r++ e+ + +++ ve+ + +l +l+e+ + ++++++r+ FUN_001065-T1 4760 KKdYDQMLASLKLEVEQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRT 4823 7537888988888888777776555555577888888999999999999999999999999997 PP == domain 31 score: -5.1 bits; conditional E-value: 6.8 Rod_CreS 27 revagltrrlsaaereleelsarlakleaalkea.eaakeelrielrektalaealErqlkaeteqnraleeelkaLraeakaaekalqeaege 119 +e+ +l++++s + +e+++ + +kl ++ ++a e +el +l ek la++ E lk+++e +++l e ++aL + + e+ ++ FUN_001065-T1 4831 DEIVELKNEISLLRKECQDCRVEKDKLYDKFHDAvESLRKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHIGKGWRND 4924 688899*************************998577789**********************************99986655555544444444 PP Rod_CreS 120 latarerlalleqEnrrLqalveeqaaelaelearlaeletal 162 l + + +E++ Lq+ ee + + + +e e+ FUN_001065-T1 4925 L-------EAARAEKELLQKQLEERTSQSVTIDIAPEEEESWQ 4960 4.......44444444444444444444444444333333322 PP >> ATG16 Autophagy protein 16 (ATG16) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -8.7 16.1 10 2.6e+04 71 181 .. 46 179 .. 4 208 .. 0.53 2 ? -9.1 25.9 10 2.6e+04 34 165 .. 227 352 .. 225 356 .. 0.73 3 ? 0.9 4.0 0.24 6.2e+02 98 160 .. 375 437 .. 362 447 .. 0.79 4 ? -12.7 32.7 10 2.6e+04 32 175 .. 456 600 .. 439 609 .. 0.53 5 ? -1.0 11.8 0.89 2.3e+03 84 149 .. 551 616 .. 545 627 .. 0.81 6 ? -6.4 15.3 10 2.6e+04 90 180 .. 683 766 .. 635 769 .. 0.65 7 ? -10.8 37.6 10 2.6e+04 34 162 .. 704 840 .. 687 848 .. 0.51 8 ! 7.6 10.0 0.0021 5.3 92 162 .. 837 907 .. 835 915 .. 0.94 9 ! 8.6 9.5 0.001 2.6 83 158 .. 912 987 .. 905 1004 .. 0.77 10 ! 11.0 10.9 0.0002 0.51 99 178 .. 1005 1084 .. 996 1089 .. 0.95 11 ! 16.4 20.5 4.2e-06 0.011 72 180 .. 1104 1212 .. 1084 1215 .. 0.88 12 ! 6.9 12.0 0.0036 9.3 72 178 .. 1230 1336 .. 1214 1341 .. 0.86 13 ! 6.5 18.6 0.0046 12 25 157 .. 1295 1431 .. 1295 1438 .. 0.84 14 ! 8.7 13.0 0.00099 2.5 88 168 .. 1439 1519 .. 1433 1521 .. 0.95 15 ! 19.6 15.8 4.7e-07 0.0012 91 184 .. 1530 1623 .. 1526 1625 .. 0.97 16 ! 13.8 15.9 2.6e-05 0.068 99 178 .. 1646 1725 .. 1634 1730 .. 0.96 17 ? -3.5 4.3 5.3 1.4e+04 88 147 .. 1733 1792 .. 1722 1825 .. 0.55 18 ? 3.1 19.6 0.05 1.3e+02 30 164 .. 1779 1908 .. 1756 1915 .. 0.67 19 ? 3.9 18.7 0.028 73 72 181 .. 1917 2026 .. 1908 2033 .. 0.93 20 ? 5.3 5.1 0.011 27 107 161 .. 1994 2048 .. 1985 2051 .. 0.82 21 ! 11.6 23.8 0.00013 0.32 66 168 .. 2047 2156 .. 2029 2160 .. 0.83 22 ! 7.0 12.0 0.0033 8.3 75 162 .. 2133 2220 .. 2131 2225 .. 0.90 23 ? -3.6 15.5 5.6 1.4e+04 99 179 .. 2261 2341 .. 2242 2349 .. 0.80 24 ? -12.8 33.8 10 2.6e+04 30 182 .. 2381 2534 .. 2350 2540 .. 0.66 25 ? -8.1 35.4 10 2.6e+04 29 177 .. 2442 2585 .. 2421 2591 .. 0.74 26 ? -2.0 21.4 1.8 4.6e+03 39 156 .. 2614 2718 .. 2600 2724 .. 0.49 27 ? -4.1 35.3 8.3 2.1e+04 32 166 .. 2702 2833 .. 2695 2844 .. 0.59 28 ? -1.7 16.2 1.5 3.8e+03 41 171 .. 2875 3011 .. 2867 3030 .. 0.67 29 ? -6.6 17.9 10 2.6e+04 32 147 .. 2912 3029 .. 2902 3069 .. 0.62 30 ? 0.5 2.6 0.32 8.1e+02 132 179 .. 3068 3115 .. 3037 3123 .. 0.83 31 ? -4.7 19.7 10 2.6e+04 27 185 .. 3264 3422 .. 3249 3424 .. 0.67 32 ? -4.8 16.3 10 2.6e+04 88 164 .. 3413 3487 .. 3408 3506 .. 0.76 33 ? -1.3 32.4 1.1 2.8e+03 63 181 .. 3527 3650 .. 3495 3656 .. 0.76 34 ? -2.4 10.5 2.4 6.2e+03 29 120 .. 3672 3765 .. 3651 3792 .. 0.70 35 ? -0.6 16.3 0.72 1.8e+03 53 151 .. 3775 3876 .. 3756 3884 .. 0.72 36 ? 1.4 27.2 0.17 4.4e+02 37 185 .. 3807 3956 .. 3801 3958 .. 0.80 37 ? 1.6 7.8 0.15 3.7e+02 100 153 .. 4128 4181 .. 4116 4189 .. 0.87 38 ? -8.7 35.6 10 2.6e+04 26 184 .. 4243 4387 .. 4219 4417 .. 0.77 39 ? -0.7 9.9 0.77 2e+03 94 176 .. 4395 4489 .. 4388 4493 .. 0.50 40 ! 8.1 10.8 0.0015 3.9 118 189 .. 4565 4636 .. 4522 4647 .. 0.88 41 ? -2.4 11.9 2.4 6.2e+03 106 167 .. 4656 4714 .. 4629 4735 .. 0.65 42 ? -2.8 18.9 3.4 8.7e+03 14 168 .. 4721 4873 .. 4709 4879 .. 0.67 43 ? -0.3 15.6 0.56 1.4e+03 81 170 .. 4863 4952 .. 4860 4961 .. 0.90 Alignments for each domain: == domain 1 score: -8.7 bits; conditional E-value: 10 ATG16 71 s..................qsakiqsleqklaqlreel.aeaqrsrgelaqrllelneelqelek...klrederrlaeleaeraqleeklkdree 144 + ++ + + e++l+qlre + a s +e+ ++++++n+ +q+ + l+++++ + +le+++++ e ++++e+ FUN_001065-T1 46 DlrralsesemrneginreFQKLLRQKEEELVQLRENVrAGPSLSPSEFPSEVQDANNPVQDIQHiqvLLAQKDEVIGDLEKQLHESEAHVRRLEQ 141 344444444455556655555566666666666666653445666666666666666655554433336666666666666666666666666665 PP ATG16 145 e.lrekaklvedlqDElvaLnlqlnmaEeklrklekEN 181 + +k++++l + a + ++Ee+++ le+ N FUN_001065-T1 142 QgCDNEEKVMHELAVKIRAAEGFQLKLEETKQLLEDRN 179 52333344444444444443333333344444444444 PP == domain 2 score: -9.1 bits; conditional E-value: 10 ATG16 34 leaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaele 129 ea na+ e++ +a+ +++ ++ k ke e+ +s+ i+s e++ + + l + q +e++q +l+l+ ++e+ek l+++ ++ +++ FUN_001065-T1 227 IEAMNARVEKSVDEARRAKREISALK---KELEE----KSELIASAEKLEQEKSSLLIQIQEIEKEHKQTVLRLQHYVEEKEKALAAEFAEAEQVY 315 56777777777666665433333333...22222....23445555555555555677888889999************************99986 PP ATG16 130 aer.aqleeklkdreeelrekaklvedlqDElvaLnl 165 +++ ++l+e+l+++++ ++ k+++++ l+ +++ nl FUN_001065-T1 316 KTNeHDLRERLDEKAQIIESKDEAIQVLKRAIQEKNL 352 6551679***********************9998777 PP == domain 3 score: 0.9 bits; conditional E-value: 0.24 ATG16 98 gelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDEl 160 +e ++++ +l+e+++ lek + ++++++ l++++ + +k ++e l++k++ ++ +++ + FUN_001065-T1 375 KEREEMIRSLSEKMNFLEKGSVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKH 437 566778888888888899999999999999999999988888888888888888887776655 PP == domain 4 score: -12.7 bits; conditional E-value: 10 ATG16 32 alleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlae 127 ++l++ a+l+ + ++ +++++ +++ +++++++ +++ q+ ++ +l +l+ ++ +++++++l+e+ +e++++ek+ + ++++ + FUN_001065-T1 456 EELQKMVASLKDSLSELESKEKVTERLL---LLDAEKEQQFRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEARAEIEAKEKEVKDLNSKIGK 548 2233333333333333333222222222...22222333334455555566666666666666666667777777777776666666666666654 PP ATG16 128 l....eaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklr 175 l +a+++ l+ + +++ +e++e++ + ++E a + + +++Ee+++ FUN_001065-T1 549 LklqaKAKVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKE 600 4111245566666666666666666666666666666666666666666665 PP == domain 5 score: -1.0 bits; conditional E-value: 0.89 ATG16 84 aqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrek 149 +q ++ ++ +q ++++l+++ +el+ l +++ + ++++++ e+e++ e+k+ ++e+ l+e FUN_001065-T1 551 LQAKAKVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQALEEF 616 566777888888888888888888888888888888888888888888888888888888888875 PP == domain 6 score: -6.4 bits; conditional E-value: 10 ATG16 90 laeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekE 180 l ++r +++++ el+e l++ +++ +++++++++ e++ + + + ve+lq+E ++L++ l+ ++l +l++E FUN_001065-T1 683 LDLITKERDSFKSKVEELEEMLEAEKEQQQKKAEEISS-------DEDAEHAKHMAEESLMMHVEALQEENETLRVSLDLEKSALANLKEE 766 55555666666666666666666665555555555543.......3333333333334455667788888888888888888888888877 PP == domain 7 score: -10.8 bits; conditional E-value: 10 ATG16 34 leaenakleseaasatpsssqstsskkskkekeasass...................qsakiqsleqklaqlreelaeaqrsr.gelaqrllelne 109 leae+++ +++a++ ++ ++++ ++ + ++ +++la l+eel++aq + +el ++ +l + FUN_001065-T1 704 LEAEKEQQQKKAEEISSDEDAEHAK------------HmaeeslmmhvealqeenetLRVSLDLEKSALANLKEELKQAQLNQeNELHSEMDSLRQ 787 3333333333333333222222111............11122233343334444334455555666677777777777776552466666666666 PP ATG16 110 elqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElva 162 l+e ++k+ ++l+ ++e+a+ +++++ +e+el++k+ +ve+l l++ FUN_001065-T1 788 VLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQ 840 66666666666666666666666666666666666666666666666555544 PP == domain 8 score: 7.6 bits; conditional E-value: 0.0021 ATG16 92 eaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElva 162 ++q+s +e ++ l ++ +e++ l+ l+e+++ + l+a+ ++ + +l++++e+l++k++ ve lq E++ FUN_001065-T1 837 QLQQSTQERNKVLEDKDKEISNLQGALMENSSGFEVLNASFSESTIQLDRLQEQLAAKEAEVERLQKEMSE 907 58899999999*********************************************************985 PP == domain 9 score: 8.6 bits; conditional E-value: 0.001 ATG16 83 laqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqD 158 ql+ + + + +e++ l +++e+l++ ++ + +++++l++l+++ +l+ ++++++ + +k++ ++ l+ FUN_001065-T1 912 HEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDDKEAEIAHLKA 987 5666777777777788888899999999999999999999999999999999999999999888888888887775 PP == domain 10 score: 11.0 bits; conditional E-value: 0.0002 ATG16 99 elaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrkle 178 e ++l++l+e +q++e++l++ +++ +e ++ ++l++ +++++ +l+++++++ + DE++ L+ +l+ +E+ l++l FUN_001065-T1 1005 ESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLA 1084 6789**********************************************************************999885 PP == domain 11 score: 16.4 bits; conditional E-value: 4.2e-06 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDE.lvaLn 164 ++ +++++e++l + e + + +s +e + ++e+n++l+++e+k ++ +++l+e a++++l+ ++ r+++l +++kl+ +++DE +++L+ FUN_001065-T1 1104 KDVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLL-IAKDEcVQTLE 1196 467889999***********************************************************************99.566663689** PP ATG16 165 lqlnmaEeklrklekE 180 +l+ +E+ ++le+E FUN_001065-T1 1197 NTLKEIEKSHQQLESE 1212 **************99 PP == domain 12 score: 6.9 bits; conditional E-value: 0.0036 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnl 165 ++++i +l++k+ +l+ + +e+ s +e +++ el + l+ +e++l+ + ++++ ++ +ql+ +l+ + +l+e++ ++ + D +++L+ FUN_001065-T1 1230 KDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLER 1323 4678999999999999999999999999999999999999999999999999999999999999999999999999999999999999999998 PP ATG16 166 qlnmaEeklrkle 178 ++ +++++le FUN_001065-T1 1324 DVEATLQQYKDLE 1336 8887777777776 PP == domain 13 score: 6.5 bits; conditional E-value: 0.0046 ATG16 25 nrLldrtalleaenakleseaasatpsssqstsskkskkekeasass.....qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqe 113 +rL+ ++++l++ + +l+++ + ++ +++ ++ ++ k +s+++ +++i++ e++ a+l +e++e+ + +el++r e+n++l++ FUN_001065-T1 1295 SRLAGQSSQLQELTITLSNKEDQISSLERDVEATLQQYKD-LESRHNsdvlkLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKA 1387 6899999999999999977766666655555554433333.3333335899999**************************************** PP ATG16 114 lekklrederrlaeleaeraqleeklkdreeelrekaklvedlq 157 l++ +e+e++l el+a++++ + lk+ ++ l+ ++ v lq FUN_001065-T1 1388 LQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQ 1431 *********************************99988877776 PP == domain 14 score: 8.7 bits; conditional E-value: 0.00099 ATG16 88 eelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqln 168 ++l+e++ +e++++l+el e l+ +e++++ +++++e +a ++qle +l++ ++ e+ +++ + E+++Ln+ l+ FUN_001065-T1 1439 ADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSLS 1519 58899999999******************************************************************9986 PP == domain 15 score: 19.6 bits; conditional E-value: 4.7e-07 ATG16 91 aeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeL 184 +e+q + g l+++l e++ee+q+le++l e+++++++l +++++ +++l+d++ +l+ k+ ++++ +aL+ ++ a +++++++kE +eL FUN_001065-T1 1530 SELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYENAVSENENIQKELDEL 1623 7899999***********************************************************************************8887 PP == domain 16 score: 13.8 bits; conditional E-value: 2.6e-05 ATG16 99 elaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrkle 178 e++++l+++nee+q lekkl +++l+ ++e+++l k+ ++++el ++++ + l DE + L+ qln+ E++++++e FUN_001065-T1 1646 EHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNME 1725 7899************************************************************************9987 PP == domain 17 score: -3.5 bits; conditional E-value: 5.3 ATG16 88 eelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelr 147 e ++++ +r+e ++ l l++el+ + ++++ ++ +++l+ +++ +++ ++++e l+ FUN_001065-T1 1733 EKMSQVEFERNEVQSGLDHLKKELDLKLREATDLREVIDHLKGVNEEISRAAAENAECLK 1792 333344444555555555555555555555555555555555555555555555555554 PP == domain 18 score: 3.1 bits; conditional E-value: 0.05 ATG16 30 rtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklreder 123 ++ +aena+ ++ a++++ + s++ s++ ++ +ak+ ++e+ ++l+++ ++ + ++rl e+ e + l+k l+e ++ FUN_001065-T1 1779 EISRAAAENAECLKTEILAKENELHKVSQSLSSNMIMLEE--IQAKLIESEKCSTKLKDDF---ELEKDDWKTRLEEAACENSSLKKGLSEMTE 1867 4444444444444333333332222222222222222222..3366666777777777765...357888999999999999999999999999 PP ATG16 124 rlaeleaeraqleeklkdreeelrekaklvedlqDElvaLn 164 + ++l+++++ ++ lk+ +eel+ k++++ +lq E++ L+ FUN_001065-T1 1868 KQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHLQ 1908 99999999999999999999999999999999999999887 PP == domain 19 score: 3.9 bits; conditional E-value: 0.028 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnl 165 qs+k ++l++++++ + e e+q++ ++ + l++++ e++el++ + e++++l+ +++++++l+e+ + +ee + +lq l+ + FUN_001065-T1 1917 QSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMAS 2010 6788899*************************************************************************************** PP ATG16 166 qlnmaEeklrklekEN 181 +l+ + +++ +le++ FUN_001065-T1 2011 ELRRVSQEKTELESDV 2026 ************9985 PP == domain 20 score: 5.3 bits; conditional E-value: 0.011 ATG16 107 lneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElv 161 + ee + l+++l+e +++l+++++e+++le + d++++lr ++ +++++++l+ FUN_001065-T1 1994 AVEETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLT 2048 5577888999999999999999999999999999999999999998888888765 PP == domain 21 score: 11.6 bits; conditional E-value: 0.00013 ATG16 66 easass....qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdree...elrekakl 152 ++as+ ++++i+sle+ +++l++ l+e+qr+ ++l + l ++n+el+ ++ +e+e++l+el++er++ +e+l+ ee +l+e + FUN_001065-T1 2047 LTNASEgittRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERLSAAEEvfsKLQEMESF 2140 3333335556899*****************************************************************9999833356677777 PP ATG16 153 vedlqDElvaLnlqln 168 +l+ E ++L+ +l+ FUN_001065-T1 2141 YGALKQEKESLKTELE 2156 7799999999998886 PP == domain 22 score: 7.0 bits; conditional E-value: 0.0033 ATG16 75 kiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElva 162 k+q++e+ +l++e + + + ++ ++ l+e ++e + l+++l + +rl++l++er+q++ +l+++++el++ ++ v lq +++ FUN_001065-T1 2133 KLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISS 2220 56788888889999999999999999************************************************99999999876655 PP == domain 23 score: -3.6 bits; conditional E-value: 5.6 ATG16 99 elaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklek 179 + ++ +l+ e + l ++l+e +l+e+++++ + ++l d +e+l+ +a + e + El+ + +++ +E++l +l++ FUN_001065-T1 2261 QQVSQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQ 2341 444555666667777778899999999999999999999999999999999999999999999999999999999998885 PP == domain 24 score: -12.8 bits; conditional E-value: 10 ATG16 30 rtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrlle.lneelqelekklrede 122 r+++l ++ + + +++ +++ q+t+ ++++ ++ +++ ++ki+ ++++a+ + la+a ++++e q+l + l ++ +++++ l+e + FUN_001065-T1 2381 RIEELTIAKELEKAQVEEKLTKQLQDTK-THKDGVIAKLKDKVREKIELNKKNIAEFKVKLANANKEKEETLQELHSqLANAEKDKKAALEELK 2473 4444433333333333333322222222.22333333333337889999999999999999999999999988886415555566666777777 PP ATG16 123 rrlaeleaeraqleeklk.dreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENk 182 l++ ++e+ q + l+ ++++ ++ek+++v++lq l+ + +++ ++l++l++ N+ FUN_001065-T1 2474 LFLDNSQKEKDQALQDLElQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRDNNR 2534 7788888888776666654788999999999999999999988889999999999998887 PP == domain 25 score: -8.1 bits; conditional E-value: 10 ATG16 29 drtalleaenakleseaasatpsssqstsskkskkekeasass...........qsakiqsleqklaqlreelaeaqrsrgelaqrllelneel 111 + ++ e+ ++l+s+ a+a++ +++ + q++k q+l+++ +ql + ae +el+++l +++ FUN_001065-T1 2442 NANKEKEETLQELHSQLANAEKDKKA----------------AleelklfldnsQKEKDQALQDLELQLAKAIAEKEEVVQELQSQLEIQSQTT 2519 22222222222222222222222222................122344555555667778888888888888888888899************* PP ATG16 112 qelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrkl 177 ++l + l + + + + +e++ l++kl d e+e ++k+ +++ +l+ L+l+ ++ E+++ ++ FUN_001065-T1 2520 EQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEM 2585 *************************************************************98665 PP == domain 26 score: -2.0 bits; conditional E-value: 1.8 ATG16 39 akleseaasatpsssqstsskkskkekeasass.......qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrl 125 ++l++e a+ kk + ++k ++ eq+ a ++eel e+++ ++l++ ++l+++ ++le+ + e ++ FUN_001065-T1 2614 KRLKEERAA-----------KKD---------ElaklqgsIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEM 2687 333222111...........111.........01111122234556666777777777777777666666555555555555555555555555 PP ATG16 126 aeleaeraqleeklkdreeelrekaklvedl 156 +l++++ + +++ kd+e++ ++++k +e++ FUN_001065-T1 2688 INLKRDLDEITKEKKDLERNHEQLKKELEEQ 2718 5555555555555555555555555555544 PP == domain 27 score: -4.1 bits; conditional E-value: 8.3 ATG16 32 alleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrs...rgelaqrllelneelqelekklrede 122 + le+ ++l++e +++++ ++s + +s++e+ ++ k+++l+ +l +l+ee++e r+ ++e +q l++ ++l+e ++l++++ FUN_001065-T1 2702 KDLERNHEQLKKELEEQETDFTSSVDALSSQREN------ADRKTEELQLQLDALNEEVSEKKREevnQQEEKQLLVDQVQQLSEAVQTLKNKD 2789 4455566666555555444333332222111111......223456777777777777777766422255566667777777777777777777 PP ATG16 123 rrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlq 166 + + +le+e++ +e+ +++e+l +++ + l+D++++L+++ FUN_001065-T1 2790 QDIVRLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYDQLQAA 2833 77777777777777777777777777777777777777777765 PP == domain 28 score: -1.7 bits; conditional E-value: 1.5 ATG16 41 leseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelek.....klrederrlaele 129 l++e+ +++s +t +++ + +++a +++++++ +l ++++el++a +++l+ ++ ++ +++ + +++ ++++++++ FUN_001065-T1 2875 LQEEIPVVQQSVPLQTEPSSVQPSEPAAG---HDDLHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSEsvrdvESSDMKAEIDKAR 2965 55555555555555555555555555554...45999999999999999999999999999999988777777666344446667778888888 PP ATG16 130 aeraqleeklkdreeel....rekaklvedlqDElvaLnlqlnmaE 171 +e+ +le+ +++eel rek+ ++ dl+ + +L + + +E FUN_001065-T1 2966 QEKINLEKTALELREELveivREKDGTIGDLKQKIRQLLNEKSRNE 3011 8888888776665555422227777777777777766666555555 PP == domain 29 score: -6.6 bits; conditional E-value: 10 ATG16 32 alleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrlle....lneelqelekklred 121 +l++ +a+l ++ a +++ + + + kke ++s+s ++ +++++++++ + r+e ++ ++ el ++l+e + ++ +l++k+r+ FUN_001065-T1 2912 MELKEIQAELTKAKALNEK--LKAKVRVFMKKERAKSESVRDVESSDMKAEIDKARQEKINLEKTALELREELVEivreKDGTIGDLKQKIRQL 3003 4566666666555433333..3333333333444444444678888888888888888888888877777776651111344455555555555 PP ATG16 122 errlaeleaeraqleeklkdreeelr 147 ++ ++ e +++ e+ l++r+ee++ FUN_001065-T1 3004 LNEKSRNEVLVEKYEKLLAERDEEIK 3029 55555555555555555555555554 PP == domain 30 score: 0.5 bits; conditional E-value: 0.32 ATG16 132 raqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklek 179 +++le + +e+ l++k++ + +++ Elv+ n++ + + +lr++++ FUN_001065-T1 3068 VQELENTKDGYEKVLSDKDEEIGNFKRELVSCNIETEELKGRLRQTQE 3115 667788888888999999999999999999999999999999998887 PP == domain 31 score: -4.7 bits; conditional E-value: 10 ATG16 27 Lldrtalleaenakleseaasatpsssqstsskkskkekeasass......qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqel 114 L + ++l ++ +++l+++ ++ +++ss + + ++e + +a ++++++a+lr el + ++++ + +++++ l FUN_001065-T1 3264 LKQASDLNNKLKEALKKKRSKPRSKSSGEHEM---SNE------TiaelevIRAAKVESDKQMAHLRLELDNFVQEKERI---VAGFKSKMEML 3345 33334444444444433332222222111111...222......1234556455556677889**********8777655...66677777777 PP ATG16 115 ekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElv...aLnlqlnmaEeklrklekE...NkeLv 185 ++ ++ ++ ++e e+++ + ++++d++ + ++ +++l+ +++ L+l+l+ +++ +le++ Nk+Lv FUN_001065-T1 3346 ADEKERANSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVEnlpELKLELQLTVQENAELENDlryNKSLV 3422 77888888899999999999999999999999999999999998876222579999999999999999866677777 PP == domain 32 score: -4.8 bits; conditional E-value: 10 ATG16 88 eelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLn 164 ++l +e +r++el+ el+ +e+k ++ ++++e ++++ l k k+ +e + e+++ + +lqD l++ FUN_001065-T1 3413 NDLRYNKSLVKESTDRVSELKRELESREEKHLKEIEEIKERHDQV--LIAKQKETDEAILELRQINTELQDNLQSVS 3487 555555555567888899999988888888888888888766665..66677799******************9976 PP == domain 33 score: -1.3 bits; conditional E-value: 1.1 ATG16 63 kekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekk.lrederrlaeleaeraqleeklkdreeelrek....ak 151 ++ e+++ ++++ i +le ++l+e+++e+ sr+el+++l e+ +e+++++ + r+ e++ +el++e++ l+++++++e++ +e+ ++ FUN_001065-T1 3527 SQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRfQRSVEEKETELREEKEGLQQQMQQLEAKFEELlsqsQA 3620 223333333578899************************************997526778889999***********99998776665222277 PP ATG16 152 lvedlqDElvaLnlqlnmaEeklrklekEN 181 + +l +El+ n++l + ekl++ E FUN_001065-T1 3621 SISKLEEELAHTNMELVSFNEKLQTADGEK 3650 7779************99999999877665 PP == domain 34 score: -2.4 bits; conditional E-value: 2.4 ATG16 29 drtalleaenakleseaasatpsssqstsskkskkekeasass..qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklre 120 +++ +a +++l e + + ++ ++s++ ++++ + + +++ s+ +++++ + a lr+ l++++ +r l++rl + + l+++ +k + FUN_001065-T1 3672 QQAINARAAAEELAHEFQVQLEKMRKSNPTTANEVDEISPPQEnkVSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVLSTKSEKEAL 3765 555566666666666666655555444444433333333333355889999999****************************999999887543 PP == domain 35 score: -0.6 bits; conditional E-value: 0.72 ATG16 53 sqstsskkskkekeasass...qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdre 143 ++++ +k ++ +s+++ +s ++++e ++ l++el+ + +++l+ +l ++ ++ + + ++ ed++ +el++e+++ +++ +re FUN_001065-T1 3775 NEDNVQKVVEEVILQSSEDnqvSSLPTSETEVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDSGDEDSSVRNELQTELEKIRQEKLERE 3868 23333333333333333334446777888999999****************************************************9999999 PP ATG16 144 eelrekak 151 + +e++ FUN_001065-T1 3869 KTCQELRL 3876 99998875 PP == domain 36 score: 1.4 bits; conditional E-value: 0.17 ATG16 37 enakleseaasatpsssqstsskkskkekeasass....qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrla 126 e ++l++e +++++ +++ +++ ++ +k++ +s+ +s+ ++l+++l ++r+e e ++++el + l + ++e+e+ ++e +rr++ FUN_001065-T1 3807 EIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDsgdeDSSVRNELQTELEKIRQEKLEREKTCQELRLE---LDTFVREKESITNELKRRID 3897 55555566666665555555544444444444333455466667899999999999999999999999965...5567999************* PP ATG16 127 eleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeLv 185 el+a++++ ++ ++d+e+++++k+ ++ +l ++ + ++a ++ ++l+ EN++L+ FUN_001065-T1 3898 ELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLL 3956 **********************************************************8 PP == domain 37 score: 1.6 bits; conditional E-value: 0.15 ATG16 100 laqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklv 153 ++r el+e+l++ ++++++ +++l+ ++++++le +++++e+el+e++++ FUN_001065-T1 4128 IETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMK 4181 56666799*****************************************99875 PP == domain 38 score: -8.7 bits; conditional E-value: 10 ATG16 26 rLldrtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklr 119 ++++ ++ +a n++l+++ ++ +++ ++ ++ s++++ ++l+++la++r+e e+ r+ ++l ++l e ++e+e++ FUN_001065-T1 4243 KMQNELDKVKAVNERLKTKLKTLMRKRKGGKVET-----------SEEENREELHTELAKVRQEKLETERAAQQLR---IDLDEIVREKERRVV 4322 5556666666777777666555554333332222...........1234556799999999999999988877776...567778999999999 PP ATG16 120 ederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeL 184 e + r++++ +e+++++ l+ +e+ l e+++++ l + +++L +l +E+ l + +EN++L FUN_001065-T1 4323 EHKTRMQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNL 4387 99999999999999999999999999999999999999999999999999999999999999988 PP == domain 39 score: -0.7 bits; conditional E-value: 0.77 ATG16 94 qrsrgelaqrllelneelqelek....klrederrlaeleaeraqleek.......lkdr.eeelrekaklvedlqDElvaLnlqlnmaEeklr 175 q ++ + + +l +++ el++l + l+e+e+r+++leae+++l+e lkdr + ++e++k +++l l +Ln + +++E++ + FUN_001065-T1 4395 QLQKVKAERELHAATGELERLLEgdrpILAEKEQRISNLEAELSDLKESfdiemrtLKDRyDVVVSEQQKHINNLESTLGSLNTEKKQLESRVK 4488 4444444444444444444443322224555666666666666666554111111155552334567777777777777777777777777666 PP ATG16 176 k 176 FUN_001065-T1 4489 A 4489 5 PP == domain 40 score: 8.1 bits; conditional E-value: 0.0015 ATG16 118 lrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeLveRWm 189 l+ +e+++++l++ +aq +e+ d+ee++ +++k+v+d + +l + q + +Ee ++l +E + e+++ FUN_001065-T1 4565 LSDNEAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEHATSMEQLV 4636 6778999*****************************************************999776666555 PP == domain 41 score: -2.4 bits; conditional E-value: 2.4 ATG16 106 elneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlql 167 ++ +++ + +k+l + +++ + l++ + +k++++e el+ek++++e+l DE+ + ++ l FUN_001065-T1 4656 NMDAAVMQSNKELDQMKEQYTLLKE---NSAKKMEQLEGELSEKRQVIEKLSDEIGQFRAGL 4714 5555555555566655555555554...445789999*****************98887665 PP == domain 42 score: -2.8 bits; conditional E-value: 3.4 ATG16 14 ekafaelieaYnrLldrtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllel 107 ek+++el ++Y+ L ++l++ +e+++ + + ++ + ++ k + ++s +++ + e+ ++ +r e++ + r ++ l ++l e+ FUN_001065-T1 4721 EKLYEELQANYQLLETGNNKLRQDLYLTMKETENLRM-KLKKDYDQMLASLKLEVEQS-RQQNLEKEKFIHNQRIEVESLVRDKESLITKLRET 4812 5566666555555444444444444444333333333.22222223333333333333.6778899999**********************997 PP ATG16 108 neelqe...lekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqln 168 + +e + + ++d+ ++ el++e++ l+++++d + ek+kl ++++D++++L+ +l+ FUN_001065-T1 4813 GQVTREtlqRTDGDAADDDEIVELKNEISLLRKECQDCR---VEKDKLYDKFHDAVESLRKELE 4873 55444400044456788999***************9977...579**************98875 PP == domain 43 score: -0.3 bits; conditional E-value: 0.56 ATG16 81 qklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnma 170 +++ +lr+el+ ++ ++ +laq+ e+ ++ +el+++l e++++l++++ + ++ + ++ e r+ ++l++++ +E ++ ++ + a FUN_001065-T1 4863 DAVESLRKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHIGKGWRNDLEAARAEKELLQKQLEERTSQSVTIDIA 4952 67899*********************************************************************9999988877666665 PP >> FKBP15 FK506-binding protein 15-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -8.3 12.3 10 2.6e+04 116 196 .. 106 183 .. 54 212 .. 0.59 2 ? -10.6 33.6 10 2.6e+04 51 210 .. 168 340 .. 162 355 .. 0.66 3 ? -11.2 32.6 10 2.6e+04 44 210 .. 333 508 .. 324 518 .. 0.54 4 ! 7.0 23.8 0.0022 5.7 91 193 .. 519 618 .. 510 646 .. 0.88 5 ? -4.8 49.3 8.6 2.2e+04 41 221 .. 669 860 .. 666 866 .. 0.79 6 ? 3.1 17.6 0.033 84 88 196 .. 882 990 .. 872 999 .. 0.74 7 ! 9.3 15.8 0.00042 1.1 89 198 .. 981 1090 .. 977 1096 .. 0.89 8 ! 5.5 24.9 0.0063 16 59 190 .. 1074 1215 .. 1072 1220 .. 0.82 9 ? 3.6 11.0 0.023 59 86 175 .. 1181 1270 .. 1175 1291 .. 0.83 10 ? 2.7 30.2 0.046 1.2e+02 21 221 .. 1222 1431 .. 1219 1433 .. 0.81 11 ? 2.0 25.6 0.074 1.9e+02 58 196 .. 1374 1512 .. 1370 1522 .. 0.83 12 ! 18.9 25.8 4.9e-07 0.0013 83 218 .. 1515 1656 .. 1510 1665 .. 0.83 13 ? -3.6 26.6 3.9 1e+04 87 194 .. 1655 1761 .. 1632 1793 .. 0.49 14 ? -3.0 34.8 2.4 6.2e+03 12 190 .. 1780 1951 .. 1776 1952 .. 0.68 15 ! 7.9 19.4 0.0011 2.9 85 212 .. 1923 2050 .. 1915 2053 .. 0.92 16 ? 3.8 26.5 0.02 52 85 190 .. 2049 2157 .. 2035 2160 .. 0.72 17 ! 8.8 13.7 0.00059 1.5 79 159 .. 2144 2224 .. 2142 2234 .. 0.69 18 ? -1.7 34.5 0.96 2.5e+03 59 211 .. 2249 2405 .. 2244 2421 .. 0.85 19 ? -9.7 45.4 10 2.6e+04 27 192 .. 2409 2586 .. 2402 2605 .. 0.81 20 ? 0.8 33.0 0.17 4.4e+02 87 211 .. 2599 2724 .. 2578 2733 .. 0.67 21 ? -5.3 27.1 10 2.6e+04 107 211 .. 2715 2818 .. 2714 2835 .. 0.63 22 ? -1.3 20.7 0.76 1.9e+03 103 214 .. 2906 3022 .. 2896 3030 .. 0.73 23 ? 3.0 16.3 0.037 95 26 192 .. 2986 3156 .. 2980 3169 .. 0.82 24 ? 0.2 13.8 0.27 6.8e+02 101 214 .. 3261 3364 .. 3239 3374 .. 0.73 25 ? -4.9 53.2 9.7 2.5e+04 12 223 .. 3401 3610 .. 3395 3614 .. 0.81 26 ? 3.3 34.1 0.03 77 66 216 .. 3516 3674 .. 3505 3678 .. 0.72 27 ? -2.7 12.1 2 5.2e+03 70 156 .. 3616 3702 .. 3610 3753 .. 0.58 28 ? -7.2 7.0 10 2.6e+04 100 139 .. 3717 3756 .. 3689 3795 .. 0.65 29 ? -14.3 34.9 10 2.6e+04 91 216 .. 3802 3920 .. 3712 3924 .. 0.75 30 ! 6.2 16.0 0.0039 9.9 104 215 .. 3882 3993 .. 3876 4005 .. 0.83 31 ? -3.6 13.1 3.7 9.4e+03 91 168 .. 3992 4070 .. 3987 4109 .. 0.57 32 ! 5.6 11.2 0.0059 15 98 186 .. 4098 4186 .. 4069 4193 .. 0.59 33 ? -8.2 24.6 10 2.6e+04 102 208 .. 4232 4344 .. 4211 4352 .. 0.69 34 ! 9.2 28.0 0.00045 1.2 12 187 .. 4328 4507 .. 4310 4548 .. 0.67 35 ! 4.9 17.1 0.0096 24 117 224 .] 4564 4675 .. 4530 4675 .. 0.80 36 ? -13.3 36.4 10 2.6e+04 20 220 .. 4687 4893 .. 4677 4895 .. 0.72 37 ? -12.0 33.0 10 2.6e+04 19 195 .. 4774 4946 .. 4772 4975 .. 0.75 Alignments for each domain: == domain 1 score: -8.3 bits; conditional E-value: 10 FKBP15 116 sklssalqesekqkeeleklraqveeleekveelkqq.lkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaa 196 +++++++ +++++e + +l++q +e+e++v +l+qq + +e + el k+++ e + + e++++ l+dr k ++ FUN_001065-T1 106 QDIQHIQVLLAQKDEVIGDLEKQLHESEAHVRRLEQQgCDNEEKVMHELAVKIRAAEG----FQLKLEETKQLLEDRNKTVE 183 4455555555666666667777777777777776655245555556666666665543....22223333333333333332 PP == domain 2 score: -10.6 bits; conditional E-value: 10 FKBP15 51 vEqsnlllEqrndslkstaeq..sqarvleleqek...........vklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeele 133 +E+ ++llE rn +++ + + +q+r++e + +e + ++q+ ++ ++++ +++ + ++s++++e+e+++e ++ FUN_001065-T1 168 LEETKQLLEDRNKTVEGLMDRldAQKRLIEGRDQVidqlkamknldSGADELVGTLREQIEAMNARVEKSVDEARRAKREISALKKELEEKSELIA 263 6788888888888887766532277777775443222222332322222222355677888888888888888899999***************** PP FKBP15 134 klraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerkrleeeleelk 210 + ++ ++e+ + + ++++ ke Kq+ +l++ +++ e la ae+e++ k+ + + +e++++ e +e+ FUN_001065-T1 264 SAEKLEQEKSSLLIQIQEIEKEHKQTVLRLQHYVEEKEKALAAEFAEAEQVYKTNEHDLRERLDEKAQIIESKDEAI 340 *************************9888877777777666666666666666554444444444444444444433 PP == domain 3 score: -11.2 bits; conditional E-value: 10 FKBP15 44 leknqryvEqsnlllEqrndslkstaeqsq.arvleleqekvklteeLaaataq....l....selqlelaalqkkeaelqsklssalqesekqke 130 +e++++ + ++ + ++n s + ++ s+ ++v++l +ekvk ee+ + ++ l + ++e++ l+k + s+++ ++++++ +++ FUN_001065-T1 333 IESKDEAIQVLKRAIQEKNLSSEGSSPPSHsDKVMALLEEKVKEREEMIRSLSEkmnfLekgsVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQ 428 555555555555555556655555555444167888888887766665333222000021111223455666666666666666666666666666 PP FKBP15 131 eleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesleksl...sdrkkkaaeerkrleeeleelk 210 e++ +++++e ++++e + +l ++ +++ el++ ++sl++ l++l+++++ +e+ l +++ +++ +e++ + + + l+ FUN_001065-T1 429 EIAGIKEKHE---TEMSEKEMKLSSQIKSNEELQKMVASLKDSLSELESKEKVTERLLlldAEKEQQFRDEKQAFHDSEKALH 508 6665555443...3333334444444456677788888888888888888888888642223455566666666666555555 PP == domain 4 score: 7.0 bits; conditional E-value: 0.0022 FKBP15 91 aaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslek 186 ++ + +l e+ e++a +k+ ++l+sk+ +++ +++ +++ l++++e l ++++el+ +l +e++++ ++++k++++eee + ++++ +le+ FUN_001065-T1 519 SKMSDELIEARAEIEAKEKEVKDLNSKIGKLKLQAKA---KVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQ 611 5678899999*******************99987765...9999**************************************************** PP FKBP15 187 slsdrkk 193 +l++ + FUN_001065-T1 612 ALEEFVR 618 *998544 PP == domain 5 score: -4.8 bits; conditional E-value: 8.6 FKBP15 41 seLleknqryvEqsnlllEqrndslkstaeqsqarvleleqek.......vklteeLaaataql.selqlelaalqkkeaelqsklssalqesekq 128 + le++ ++E++ l+ + ds+ks e+ + +le+e+e+ ++ +e+ ++a+ +l + ++alq++++ l+ l+ ++ +++ FUN_001065-T1 669 MKILEEERYCMERRLDLITKERDSFKSKVEE-LEEMLEAEKEQqqkkaeeISSDEDAEHAKHMAeESLMMHVEALQEENETLRVSLDLEKSALANL 763 5788999999******************999.7889999999865566554444455444444413577889999999999*****9999999999 PP FKBP15 129 keeleklr.aqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerkrleeeleelkksle...eeiqsL 220 keel++ + +q++el++++++l+q l eeK+k+ +l ++l+ + e+a ++ e+le++l+ ++ +++ ++l++ ++e +k le +ei++L FUN_001065-T1 764 KEELKQAQlNQENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQERNKVLEdkdKEISNL 859 999999874677899999*******************************99********9998888877766666666655555444111666666 PP FKBP15 221 r 221 + FUN_001065-T1 860 Q 860 5 PP == domain 6 score: 3.1 bits; conditional E-value: 0.033 FKBP15 88 eeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekes 183 +L+ ++ql + e+++lqk+ +e ++ ++++ ++ ++++++++ +++ee+++ +++++ ++ ++ +l ++ ++l +e+++l++ + FUN_001065-T1 882 IQLDRLQEQLAAKEAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDD 977 466777777777777777777777777777777778888888888888888888888888888888888888888888888888888888888777 PP FKBP15 184 lekslsdrkkkaa 196 e++++ k ++ FUN_001065-T1 978 KEAEIAHLKATTD 990 7777776665554 PP == domain 7 score: 9.3 bits; conditional E-value: 0.00042 FKBP15 89 eLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaeke 182 e+a+ +a e ++ ++l++ e +s+l+ +++ + +++el+++r++ e+ +++++l+q + e+ + + l+e l + e+e++dl ++ e FUN_001065-T1 981 EIAHLKATTDEKDMSFEHLNTSLIESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLE 1074 566666666777778889999999********************************************************************** PP FKBP15 183 slekslsdrkkkaaee 198 + e+sl+d + +e FUN_001065-T1 1075 NQEASLKDLATRCEES 1090 ********87777665 PP == domain 8 score: 5.5 bits; conditional E-value: 0.0063 FKBP15 59 Eqrndslk...staeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveel 149 E++ slk + e+s+++v ele + ++ + eL+a ++ l e le ++l+k ae + +++++++++k++e+ + l+a+ +e+++++e+l FUN_001065-T1 1074 ENQEASLKdlaTRCEESMTKVRELEGNCASKDVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKL 1167 6666666611145689****************************************************************************** PP FKBP15 150 kqql..keeKqkrke..l...eekltsleeeladlkaekeslekslsd 190 ++++ ++ K + l +e +++le+ l+++++++++le +l++ FUN_001065-T1 1168 TSDCshRDAKLDDLQklLiakDECVQTLENTLKEIEKSHQQLESELNE 1215 998722555544322112222566889999999999999999988887 PP == domain 9 score: 3.6 bits; conditional E-value: 0.023 FKBP15 86 lteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeela 175 l++ L a + + +l++ l++++k ++l+s+l++a+ + + k+++++ +++ l ekv l+ ++ e K + e+++++++l + l+ FUN_001065-T1 1181 LQKLLIAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMKNDIANKDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLT 1270 566678888899999999999999999999999999999999999999999999999999999999999999999999999998877554 PP == domain 10 score: 2.7 bits; conditional E-value: 0.046 FKBP15 21 rLkkevleksskieeqnekiseLl....eknqryvEqsnlllEqrnd.slkstaeqsqar..vleleqekvklteeLaaataqlselqlelaal 107 +k ++ +k++ i +++ek+++L e + ++ E s+++ E +lk+t + r v + +lt++La ++ql el+ l++ FUN_001065-T1 1222 GMKNDIANKDEEIVTLTEKVGALNldyeEMKTSFSEASSQMRELHDLlTLKETEL-TVLRtsVENQGSSHQQLTSRLAGQSSQLQELTITLSNK 1314 69*********************73333445569999999999876424444433.333312444444559*****************999999 PP FKBP15 108 qkkeaelqsklssalqese....kqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaae 197 + + + l+ +++++lq+++ ++++++ kl+++ +e+e++ ++l +++ke + el+++ ++ + l+ l++ ++ e++l + k e FUN_001065-T1 1315 EDQISSLERDVEATLQQYKdlesRHNSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASL-E 1407 9998888888887777765222267788999********************************************************99865.6 PP FKBP15 198 erkrleeeleelkksleeeiqsLr 221 e+ + ++++++ ++ e+e+ L+ FUN_001065-T1 1408 EKTACLKQMDDSLQRTETEVLRLQ 1431 89999999**99999999998776 PP == domain 11 score: 2.0 bits; conditional E-value: 0.074 FKBP15 58 lEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkq 151 l+ rn+ +++ + q+ e e+e +l+++L++ ta l++++ l++++++ lqs l++ l+++e+++ ++ ++q +el+e++ + ++ FUN_001065-T1 1374 LNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSILDEKLADLEESRMGFAENSNQLNELRERLRNKEE 1467 5567777777777777777788888899999999999999999999999999999999999999999999999999999999999999999999 PP FKBP15 152 qlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaa 196 + K++ e ++ +++le la++ ++ +l ++ls + k ++ FUN_001065-T1 1468 ESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVD 1512 999999999999999999999999999999999999988877665 PP == domain 12 score: 18.9 bits; conditional E-value: 4.9e-07 FKBP15 83 kvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeelad 176 +++l+ee +++selq ++ alq++ ae ++++++++++++++++ +++l+++ +++ +++e+l++ql ++ k ++++k+++l+ ++ FUN_001065-T1 1515 NMSLSEECFYFDSRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYEN 1608 677888888889********************************************************************************** PP FKBP15 177 lkaekeslekslsd.rkkk..aaeerkrlee...eleelkksleeeiq 218 +e+e+++k+l + rk + + ee+ +e+ +l e k++l+++ + FUN_001065-T1 1609 AVSENENIQKELDElRKERevFLEEKDAMEKcltQLIEHKNQLQAKNE 1656 **************5444422346775555411166677777664443 PP == domain 13 score: -3.6 bits; conditional E-value: 3.9 FKBP15 87 teeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkae 180 +ee + +++l +++ l+ ++++ l +k+ +++qe+ ke+ ++l ++ el++++++++++ k+ + e +ek++++e e +++++ FUN_001065-T1 1655 NEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSG 1748 2233333344444444444444444444444444444444445555555555555555555555555555555555555555555555555555 PP FKBP15 181 keslekslsdrkkk 194 ++l+k+l k + FUN_001065-T1 1749 LDHLKKELD-LKLR 1761 555555442.3333 PP == domain 14 score: -3.0 bits; conditional E-value: 2.4 FKBP15 12 IqrivqEN.erLkkevleksskieeqnekiseLleknqryvEqsn.lllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqle 103 I r EN e+Lk e+l k++ +k+s+ l +n ++E+ + +l+E+ + s k + e ek + +++L++a + s+l++ FUN_001065-T1 1780 ISRAAAENaECLKTEILAKENEL----HKVSQSLSSNMIMLEEIQaKLIESEKCSTKL--------KDDFELEKDDWKTRLEEAACENSSLKKG 1861 66666666456777777775544....4566666665555555441233333333222........2356788888899999999999999999 PP FKBP15 104 laalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrk...eleekltsleeeladlkaekeslekslsd 190 l+++++k+ l+++l+ +++++++++eele ++q + l+++v++l++ +kee +++ +l+ +++ + e+ +l+++ ++ + l+d FUN_001065-T1 1862 LSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHLQNVVKEEVLQSQkgeTLTDEIHAKKLEILELQKQLKQQQHLLND 1951 999999999999999999999999999999999999999999999999999986555401144455555556677777776666666666 PP == domain 15 score: 7.9 bits; conditional E-value: 0.0011 FKBP15 85 klteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlk 178 lt+e+ a + ++ elq++l+++q+ ++ + +++++++ s ++k++l+ +++ eel e+ + l+++ + ++ +l++ l+++ el + FUN_001065-T1 1923 TLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMASELRRVS 2016 6899****************************************************************************************** PP FKBP15 179 aekeslekslsdrkkkaaeerkrleeeleelkks 212 +ek +le + d k k + ++l++ e+l ++ FUN_001065-T1 2017 QEKTELESDVFDLKDKLRSADRELDAIKEDLTNA 2050 **********999999988888777766666555 PP == domain 16 score: 3.8 bits; conditional E-value: 0.02 FKBP15 85 klteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkelee...kltsleeela 175 + +e +++ ++q+++l+++ ++l+ +e+q k +++++++ek+++el+ ++ +e+e+k+eel+++ e+K++ ++ee kl+++e FUN_001065-T1 2049 NASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERLSAAEEvfsKLQEMESFYG 2142 3344455666677777777777777777777777777777888888888899999999999999999999999887766652226777777788 PP FKBP15 176 dlkaekeslekslsd 190 lk+ekesl+ +l+d FUN_001065-T1 2143 ALKQEKESLKTELED 2157 999999999999998 PP == domain 17 score: 8.8 bits; conditional E-value: 0.00059 FKBP15 79 leqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqk 159 l qek +l++eL+ ++ l e+++e ++l + ++ l+s+++e e+ ++ele+l+++ +++e++v+ l++++ + q+ FUN_001065-T1 2144 LKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSMEQR 2224 667777777777777777777777777777777777777777777777777777777777777777777777766554444 PP == domain 18 score: -1.7 bits; conditional E-value: 0.96 FKBP15 59 EqrndslkstaeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqq 152 ++ n+++ s +q +++ +l+ ek +l +eL+++ ++l e+++ + ++ + ++kl+++ ++e ++ele+++++ +e+e+++++lkq+ FUN_001065-T1 2249 NEENSGFPSLEKQQVSQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQK 2342 57899999999********************************************************************************998 PP FKBP15 153 lkee...Kqkrkeleekltsleeeladlkaekes.lekslsdrkkkaaeerkrleeeleelkk 211 ee K++r + +e+l +eel+ +++ e + k +++ + e++++ee+l ++ + FUN_001065-T1 2343 HLEEnssKEERDKSDERLLFRQEELKLMQSYSEDvVTKRIEELTIAKELEKAQVEEKLTKQLQ 2405 766534488888999999999*******99766526889999999999999888887655433 PP == domain 19 score: -9.7 bits; conditional E-value: 10 FKBP15 27 leksskieeqnekiseLleknqryvEqsnlllEqrndslkstaeqsqarvleleqek........vklteeLaaataqlselqlelaa....lq 108 + k+ i ++++k+ e +e n++ + + + l + n ++t ++ ++++ ++e++k + l+++ ++ + l +l+l+la+ + FUN_001065-T1 2409 THKDGVIAKLKDKVREKIELNKKNIAEFKVKLANANKEKEETLQELHSQLANAEKDKkaaleelkLFLDNSQKEKDQALQDLELQLAKaiaeKE 2502 56777799************************************************96666665544455555666677777777655111145 PP FKBP15 109 kkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrk 192 + +elqs+l+ +q++e+ +++l++lr +++ + ++e lk++l + ++ k+ e k ++ +l++lk e e+ e++ + FUN_001065-T1 2503 EVVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEMD 2586 55689999999999*********************************************9999999999998888887665543 PP == domain 20 score: 0.8 bits; conditional E-value: 0.17 FKBP15 87 teeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklra.qveeleekveelkqqlkeeKqkrkeleekltsleeeladlka 179 +++++ ++ +s+l+++l++ + +++ +kl+ + +e++ + e+l+ +++ + e ++++++l+++ ++ K kr +le+ ++ e+e+ +lk+ FUN_001065-T1 2599 DKSITDRNKLISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQLKAMHEeELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKR 2692 33444455556666666666666666666666666666666666666554414457788999999999999*********************** PP FKBP15 180 ekeslekslsdrkkkaaeerkrleeeleelkk 211 + +++ k+ +d +++++ +k+lee+ + + FUN_001065-T1 2693 DLDEITKEKKDLERNHEQLKKELEEQETDFTS 2724 ****9997777777777777766665544444 PP == domain 21 score: -5.3 bits; conditional E-value: 10 FKBP15 107 lqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerk 200 l+++e++++s +++++++ e+++ + e+l+ q l+e+v+e k++ +++++++ l ++++l e ++ lk++ + + + l++ + ++ee+ FUN_001065-T1 2715 LEEQETDFTSSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQTLKNKDQDIVR-LENELQLSQEEKL 2807 56667777777777777777777777777777777777777777777777777777777777777777777777666666.5555555566665 PP FKBP15 201 rleeeleelkk 211 +l e+l l++ FUN_001065-T1 2808 QLAEQLTSLNE 2818 55555554443 PP == domain 22 score: -1.3 bits; conditional E-value: 0.76 FKBP15 103 elaalqkkeaelqsklssalqesekqkeeleklraqveelee.....kveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdr 191 +l++++ + +e+q++l++a++ +ek k+++ ++++ + e +++++k+++ + +q++ +le+++ +l+eel ++ +ek+ + l+ + FUN_001065-T1 2906 DLHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSEsvrdvESSDMKAEIDKARQEKINLEKTALELREELVEIVREKDGTIGDLKQK 2999 45566667777777777777777777777765544444433301111345678889999*********************************** PP FKBP15 192 kkkaaeerkrleeeleelkksle 214 ++ +e++r e +e+ k l FUN_001065-T1 3000 IRQLLNEKSRNEVLVEKYEKLLA 3022 ********999877776665444 PP == domain 23 score: 3.0 bits; conditional E-value: 0.037 FKBP15 26 vleksskieeqnekiseLle...knqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqle.laalqkkeaelq 115 v ek+ i ++++ki +Ll+ +n+ +vE+ ++ll +r + +k+ +++ l ++ e+ + +++ + +le +++l++++ ++ FUN_001065-T1 2986 VREKDGTIGDLKQKIRQLLNeksRNEVLVEKYEKLLAERDEEIKRIGANADVEAQGLRDRCQHVLEDKEFLVKKIQQEKLEyVQELENTKDGYE 3079 779****************83334677**********************987666666555555555555555555555554678888888999 PP FKBP15 116 sklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrk 192 + ls +e + k el + + ++eel+ ++ +++++ e + + + ++ ++ l+ +l+ +ek +++ + + FUN_001065-T1 3080 KVLSDKDEEIGNFKRELVSCNIETEELKGRLRQTQESFDELNKLKVDFDHIISGLRGDLQQALEEKAVADQLAHEFR 3156 99999999999***********************************************9999999998888776655 PP == domain 24 score: 0.2 bits; conditional E-value: 0.27 FKBP15 101 qlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkk 194 q+e k++++l++kl++al+++ +k r++++ ++e ++e+ ++l ++++ e ++++++l+ el++ +eke++ + + + FUN_001065-T1 3261 QNE----LKQASDLNNKLKEALKKK------RSKPRSKSSGEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFVQEKERIVAGFKSKMEM 3344 222....233444444444444433......335566667777778888888999999999999999999999999999999999999999999 PP FKBP15 195 aaeerkrleeeleelkksle 214 a+e++r+++ +ee k+l FUN_001065-T1 3345 LADEKERANSLIEEYEKQLL 3364 99999999999999988875 PP == domain 25 score: -4.9 bits; conditional E-value: 9.7 FKBP15 12 IqrivqENerLkkevleksskieeqnekiseLle....knqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselq 101 +q vqEN +L ++ +s + e ++++seL + ++++++ + +++ E+ +l + +++ + +lel q + +l+++L++ + + + FUN_001065-T1 3401 LQLTVQENAELENDLRYNKSLVKESTDRVSELKRelesREEKHLKEIEEIKERHDQVLIAKQKETDEAILELRQINTELQDNLQSVSDNRDATE 3494 5778**************************98651212677899999999******************************************** PP FKBP15 102 lelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkka 195 +el ++ k l++ ++ + e++++++++l +q ee++ +++++ ql +++ +l+e++++le ++lk++ e++++++ ++ ++ FUN_001065-T1 3495 RELIGTRAK---LEQVVQDSYPVIEEKSQKIQELLSQMEENRINADNVIVQLE---RSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRF 3582 **9998866...56666666777777777888888888888888877776664...35567788888888888888888888888888888888 PP FKBP15 196 aeerkrleeeleelkksleeeiqsLrek 223 + ++ e el e k+ l++++q+L +k FUN_001065-T1 3583 QRSVEEKETELREEKEGLQQQMQQLEAK 3610 8888888888888888888888888766 PP == domain 26 score: 3.3 bits; conditional E-value: 0.03 FKBP15 66 kstaeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeele.klraqveeleekveelkqqlkeeKq 158 ++ +++ q+ + ++e+++++ ++ + + + + s+lq+++++l+ ++el+++l+++ +e +kq+ + + +++++++el+e+ e l+qq+++ + FUN_001065-T1 3516 EEKSQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRFQrSVEEKETELREEKEGLQQQMQQLEA 3609 4566677777889999999999999999999999999999999999999999999999999888777624677778888888888888877655 PP FKBP15 159 krk....eleekltsleeeladlkaekeslekslsd...rkkkaaeerkrleeeleelkksleee 216 k + ++ +++leeela + e s +++l+ k+ +++ r+ +++ + l+ l++ FUN_001065-T1 3610 KFEellsQSQASISKLEEELAHTNMELVSFNEKLQTadgEKQDIEKLRNNFDHIISGLRGDLQQA 3674 54411115567788899999888888888877654322566666666666766666666666665 PP == domain 27 score: -2.7 bits; conditional E-value: 2 FKBP15 70 eqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkee 156 +qsqa + +le+e ++ + eL + +++l +++ e + ++k ++++ +s + +++++ ++ + ++ ++e + ++e+++++ + FUN_001065-T1 3616 SQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRNNFDHIISGLRGDLQQAINARAAAEELAHEFQVQLEKMRKSNPTT 3702 678888888888888888888888888887777777777777766666666666666665555555555555555555555443333 PP == domain 28 score: -7.2 bits; conditional E-value: 10 FKBP15 100 lqlelaalqkkeaelqsklssalqesekqkeeleklraqv 139 + + l+a+q++ea+l++ l+++l e + +++l + + FUN_001065-T1 3717 VSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVL 3756 4556777888888888888888877777777666654332 PP == domain 29 score: -14.3 bits; conditional E-value: 10 FKBP15 91 aaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesl 184 ++++ ++ +l++el+++++ +++l++kl ++ ++ + + + + e+ + +el+++l + +q++ e e++ ++l+ el+ +ekes+ FUN_001065-T1 3802 SETEVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVK-------SDSGDEDSSVRNELQTELEKIRQEKLEREKTCQELRLELDTFVREKESI 3888 44455566666666666666666666666665554443.......3344567777788888888889999999999999999999999999999 PP FKBP15 185 ekslsdrkkkaaeerkrleeeleelkksleee 216 ++l+ r ++ ++ + +e+l ++++++ FUN_001065-T1 3889 TNELKRRIDELSAKNEKSNTLIEDLEAQVKQK 3920 99999999999888899998899888888775 PP == domain 30 score: 6.2 bits; conditional E-value: 0.0039 FKBP15 104 laalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaae 197 + + + +el+ ++++++++ek+++ +e+l+aqv++++ ++ el +++ + + ++ + +++l+ e adl aeke l + ++ k + e FUN_001065-T1 3882 VREKESITNELKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLLAEKEDLISQSKEHEKDSSE 3975 55667778999*********************************************************************99999999999999 PP FKBP15 198 erkrleeeleelkkslee 215 + +e+ +ee ++ l++ FUN_001065-T1 3976 LKVYYESLVEEYNSLLDK 3993 887777777776654443 PP == domain 31 score: -3.6 bits; conditional E-value: 3.7 FKBP15 91 aaataqlselqlelaalq.kkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleeklt 168 ++ ++ +l+++l++++ k ++el+++ ++ + + ++++++l++++ + ++ e+lk+qlk+ K++r ++ + + FUN_001065-T1 3992 DKKDRSIAHLENQLDEVTeKYKTELRATRDQHEGIILQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKH 4070 4555556666666665431335666666666666666666666666666666666666666666666666554433222 PP == domain 32 score: 5.6 bits; conditional E-value: 0.0059 FKBP15 98 selqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslek 186 e q +l++l+k + ++ +++ ++++ +++ e+l+++ +++++++++ l K+ +++le+ +++le el++ ++ k ++ k FUN_001065-T1 4098 HEFQVQLKHLEKVSGNSGTQFENVAVDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMKVNIGK 4186 44555555555555555555555555555555555555555555555555555555555555556666666666666655555555555 PP == domain 33 score: -8.2 bits; conditional E-value: 10 FKBP15 102 lelaalqkkeaelqsklssalqesekqkeeleklraqv......eeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesleksls 189 +e+++++ + ++q++l+++++ +e+ k++l++l ++ + +ee+ eel+++l + +q++ e e+ +++l+ +l+++ +eke+ + + FUN_001065-T1 4232 EEVQKVRDDWYKMQNELDKVKAVNERLKTKLKTLMRKRkggkveTSEEENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREKERRVVEHK 4325 4455555555667777888777777777777777655411111144567778888888888999999999999999999999999888777777 PP FKBP15 190 drkkkaaeerkrleeelee 208 r +++ +e++++++ le FUN_001065-T1 4326 TRMQQVLTEKEKVNNLLET 4344 7777777888888777765 PP == domain 34 score: 9.2 bits; conditional E-value: 0.00045 FKBP15 12 IqrivqENerLkkevleksskieeqnekiseLleknqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqle.. 103 +q++++E e+ + + k++ e + is L+e+ q++ ++ +++ Eq+ s + + ++ + +l+ +kvk + eL aat +l +l + FUN_001065-T1 4328 MQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEV-EQSLAQAMSENRNLNTVLEQLQLQKVKAERELHAATGELERLLEGdr 4420 3444444444444444444444455555555555555554444443.22222222222233334557888999999999999999988865333 PP FKBP15 104 ..laalqkkeaelqsklssalqesekqkeel.eklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesleks 187 la+ +++ ++l+++ls ++++ + + +l +++++ v+e+++++++l+++l + ++k+le+++++ e+ ++d+ + + + + FUN_001065-T1 4421 piLAEKEQRISNLEAELSDLKESFDIEMRTLkDRYDVVVSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTNFDHI 4507 347889999999999999999998876655526788899999999999999999999999999999999999999988777766655 PP == domain 35 score: 4.9 bits; conditional E-value: 0.0096 FKBP15 117 klssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrk....kkaaeerkrleeel 206 ls ++e e+ ++++++ r+++ +lee+v l + +++ K e +e++++lee+++ l ae+ + ++l k +e rk+++ ++ FUN_001065-T1 4564 VLSDNEAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEHATSMEQLVLEVnkagKERDEIRKEMQINM 4657 478889999999*************************************************999876555544444001134455567777788 PP FKBP15 207 eelkksleeeiqsLrekl 224 + + ++++e+++++e++ FUN_001065-T1 4658 DAAVMQSNKELDQMKEQY 4675 999999*********997 PP == domain 36 score: -13.3 bits; conditional E-value: 10 FKBP15 20 erLkkevleksskieeqnekise....Lleknqr..yvEq...snlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqlel 104 e+L e+ ek + ie++ + i++ L++k+++ + E+ + +llE n+ l++ + + e e+ ++kl+++ + l +l+le+ FUN_001065-T1 4687 EQLEGELSEKRQVIEKLSDEIGQfragLVNKSDEekLYEElqaNYQLLETGNNKLRQDLYLT---MKETENLRMKLKKDY---DQMLASLKLEV 4774 889999***************87333366654322244431113456666666666555443...345566666666654...45688999999 PP FKBP15 105 aalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlk...eeKqkrkeleekltsleeeladlkaekeslekslsdrkkka 195 ++ ++++ e ++ +++ e e+ + e+l ++ +e+ + e+ q++ ++ + el++ ++ l+ e++d + ek++l + d FUN_001065-T1 4775 EQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRTDgdaADDDEIVELKNEISLLRKECQDCRVEKDKLYDKFHDAVESL 4868 999999999999999888888888777777777777776555444444431113345566899999**************************** PP FKBP15 196 aeerkrleeeleelkksleeeiqsL 220 +e +r +e ++l ++ ee++++ FUN_001065-T1 4869 RKELERSLHEKDNLAQKTEETLKQN 4893 *****************99999875 PP == domain 37 score: -12.0 bits; conditional E-value: 10 FKBP15 19 NerLkkevleksskieeqnekiseLleknqryvEqsnlllEqrndslkstaeqsqa..rvleleqekvklteeLaaataqlselqlelaalqkk 110 e+ ++ +lek++ i +q + L++ +++++ + ++ + ++l++t +++ ++el +e l +e + + + +l ++ FUN_001065-T1 4774 VEQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRTDGDAADddEIVELKNEISLLRKECQDCRVEKDKL---YDKFHDA 4864 57789999*****************************************99886541146666666666666655544433333...3445556 PP FKBP15 111 eaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkka 195 + l+++l+ +l+e+++ ++ e++ +q++el++++ e ++ l + K + e+ + +++l+ +aeke l+k+l++r ++ FUN_001065-T1 4865 VESLRKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQ---FEHIGKGWRNDLEAARAEKELLQKQLEERTSQS 4946 6678888888888888888888888888888888888888888877764...555566778999999*************98765 PP >> Laminin_II Laminin Domain II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.8 1.1 2.8e+03 30 67 .. 105 142 .. 97 176 .. 0.73 2 ! 6.6 1.5 0.0041 11 33 100 .. 161 228 .. 148 229 .. 0.81 3 ! 6.0 8.1 0.0064 16 4 84 .. 212 288 .. 209 300 .. 0.89 4 ? -1.2 2.6 1 2.6e+03 48 93 .. 361 410 .. 316 427 .. 0.71 5 ? -4.1 6.8 8.3 2.1e+04 21 83 .. 418 477 .. 398 487 .. 0.61 6 ? 1.8 8.5 0.12 3.2e+02 20 97 .. 519 597 .. 504 601 .. 0.73 7 ? -6.6 7.2 10 2.6e+04 13 74 .. 695 752 .. 684 791 .. 0.53 8 ? -6.1 9.9 10 2.6e+04 28 80 .. 791 843 .. 760 866 .. 0.45 9 ? -5.4 8.3 10 2.6e+04 17 65 .. 815 860 .. 802 909 .. 0.64 10 ? 0.2 6.4 0.39 1e+03 16 99 .. 895 975 .. 871 986 .. 0.56 11 ? 5.3 6.3 0.01 26 4 84 .. 1009 1089 .. 1006 1099 .. 0.92 12 ! 6.2 8.9 0.0056 14 4 97 .. 1135 1225 .. 1132 1230 .. 0.86 13 ? 1.7 2.9 0.13 3.4e+02 2 76 .. 1224 1298 .. 1223 1313 .. 0.85 14 ? -0.5 8.7 0.61 1.6e+03 7 84 .. 1306 1380 .. 1282 1391 .. 0.60 15 ? -0.9 9.5 0.82 2.1e+03 8 100 .. 1388 1484 .. 1370 1485 .. 0.64 16 ! 7.0 2.9 0.0031 7.8 2 75 .. 1473 1543 .. 1472 1545 .. 0.80 17 ! 6.1 9.3 0.0057 15 8 96 .. 1539 1624 .. 1525 1626 .. 0.69 18 ? -0.7 3.6 0.75 1.9e+03 10 84 .. 1635 1709 .. 1626 1716 .. 0.77 19 ? -0.5 8.9 0.62 1.6e+03 12 82 .. 1686 1756 .. 1663 1782 .. 0.63 20 ? -5.0 8.0 10 2.6e+04 15 97 .. 1858 1909 .. 1814 1929 .. 0.49 21 ? 3.0 6.6 0.052 1.3e+02 19 96 .. 1935 2013 .. 1923 2015 .. 0.85 22 ! 19.2 8.6 5.3e-07 0.0014 3 91 .. 2003 2092 .. 2002 2099 .. 0.90 23 ! 6.2 9.7 0.0054 14 5 92 .. 2127 2218 .. 2121 2224 .. 0.78 24 ? -1.9 9.9 1.7 4.4e+03 17 86 .. 2264 2333 .. 2258 2343 .. 0.81 25 ? -2.8 2.8 3.3 8.4e+03 14 58 .. 2421 2466 .. 2411 2500 .. 0.65 26 ? -1.2 8.9 1 2.6e+03 5 81 .. 2498 2574 .. 2494 2595 .. 0.86 27 ? -1.2 11.0 1 2.6e+03 7 93 .. 2633 2716 .. 2624 2719 .. 0.82 28 ? -4.8 16.5 10 2.6e+04 12 100 .. 2694 2783 .. 2683 2788 .. 0.83 29 ? -6.7 14.4 10 2.6e+04 17 83 .. 2724 2790 .. 2709 2832 .. 0.60 30 ? -2.6 7.9 2.7 7e+03 19 84 .. 2914 2991 .. 2902 3012 .. 0.50 31 ? 2.1 0.7 0.099 2.5e+02 11 84 .. 3056 3126 .. 3042 3144 .. 0.68 32 ? -4.4 0.2 10 2.6e+04 66 79 .. 3265 3279 .. 3245 3289 .. 0.47 33 ? 3.1 1.3 0.05 1.3e+02 26 84 .. 3335 3393 .. 3322 3403 .. 0.83 34 ? -1.3 2.2 1.1 2.8e+03 9 70 .. 3423 3481 .. 3413 3499 .. 0.69 35 ? -0.0 9.8 0.45 1.2e+03 5 97 .. 3483 3573 .. 3479 3581 .. 0.82 36 ? 5.1 3.5 0.012 30 12 69 .. 3601 3658 .. 3588 3677 .. 0.82 37 ? -1.9 0.1 1.7 4.3e+03 13 63 .. 3679 3730 .. 3667 3750 .. 0.67 38 ? -6.6 8.8 10 2.6e+04 14 96 .. 3778 3861 .. 3770 3864 .. 0.72 39 ? -1.8 6.7 1.6 4.2e+03 12 78 .. 3882 3948 .. 3862 3977 .. 0.59 40 ? -0.9 5.3 0.82 2.1e+03 5 95 .. 3984 4075 .. 3981 4088 .. 0.53 41 ? 1.8 2.4 0.12 3e+02 14 68 .. 4120 4174 .. 4092 4187 .. 0.67 42 ? 0.2 2.3 0.37 9.5e+02 9 45 .. 4231 4267 .. 4226 4313 .. 0.74 43 ? 0.5 10.6 0.32 8.1e+02 16 95 .. 4311 4390 .. 4295 4403 .. 0.79 44 ? 2.4 1.6 0.079 2e+02 29 88 .. 4451 4504 .. 4420 4518 .. 0.65 45 ? -0.8 2.5 0.79 2e+03 17 81 .. 4570 4635 .. 4561 4654 .. 0.72 46 ? -3.0 6.3 3.7 9.4e+03 30 95 .. 4650 4710 .. 4619 4717 .. 0.43 47 ? -2.6 0.2 2.8 7.3e+03 30 79 .. 4764 4813 .. 4739 4849 .. 0.66 48 ? -0.6 1.3 0.69 1.8e+03 9 46 .. 4883 4920 .. 4875 4947 .. 0.78 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.1 Laminin_II 30 keklseinrsveetnekvkdankalrdArrsvkkLekl 67 +++++i+ +++ +e++ d+ k+l + + v+ Le++ FUN_001065-T1 105 VQDIQHIQVLLAQKDEVIGDLEKQLHESEAHVRRLEQQ 142 56777777777777888888888888888888888876 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0041 Laminin_II 33 lseinrsveetnekvkdankalr...dArrsvkkLeklapqLldklkelkqleeassslsdniseikelIa 100 +++++ ++eet+++++d nk+++ d ++ k L + +q++d+lk +k+l ++ + + ++e+I+ FUN_001065-T1 161 AEGFQLKLEETKQLLEDRNKTVEglmDRLDAQKRLIEGRDQVIDQLKAMKNLDSG---ADELVGTLREQIE 228 688999**********999876522267788999********************9...4577888888886 PP == domain 3 score: 6.0 bits; conditional E-value: 0.0064 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 l + a+e + eq++++++++e+ +++ +++r++ +++++++++ +++A+ kLe++ Ll +++e+++ +++ FUN_001065-T1 212 LDSGADELVGTLREQIEAMNARVEKSVDEARRAKREISALKKELEEKSELIASAE----KLEQEKSSLLIQIQEIEKEHKQ 288 5567899999999**************************************9996....8***************997765 PP == domain 4 score: -1.2 bits; conditional E-value: 1 Laminin_II 48 kdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdnis 93 + + k++++ +++vk+ e+ + L +k++ l++ ++ + s l+++i+ FUN_001065-T1 361 SHSDKVMALLEEKVKEREEMIRSLSEKMNFLEKGSVDKTSeidfLKKSID 410 467889999999*****************999999998766666444443 PP == domain 5 score: -4.1 bits; conditional E-value: 8.3 Laminin_II 21 plsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqlee 83 l++ l+ +++ +i+++ + +++++ + l + +s +L+k + L d l+el+ +e+ FUN_001065-T1 418 VLQETLQAKDQEIAGIKEK---HETEMSEKEMKLSSQIKSNEELQKMVASLKDSLSELESKEK 477 3333333334444444444...55556677777777777777788888888888877777765 PP == domain 6 score: 1.8 bits; conditional E-value: 0.12 Laminin_II 20 aplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdniseike 97 ++s +l + +++++ +++ ++++ ++ k + A+ +v L+++ ++L + ++el+++ ++ + ++is+i e FUN_001065-T1 519 SKMSDELIEARAEIEAKEKE---VKDLNSKIGKLKLQAKAKVTGLQNEKEKLSKEMQELEMHLLHEREeklaIQKKISQIEE 597 44555555555555544444...33333344566689************************99987777899*******975 PP == domain 7 score: -6.6 bits; conditional E-value: 10 Laminin_II 13 kevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldk 74 ++v+e + l+++ e+ ++k++ei ++ ++ +++ +a ++ v L+++ + L FUN_001065-T1 695 SKVEELEEMLEAEKEQQQKKAEEISSD----EDAEHAKHMAEESLMMHVEALQEENETLRVS 752 455555555556666666666666555....4455555566666666666666555555433 PP == domain 8 score: -6.1 bits; conditional E-value: 10 Laminin_II 28 ntkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkq 80 ++kek + +++e +++ ++++ ++ +r+ + ++ L+ +l++ q FUN_001065-T1 791 EEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQ 843 34444444444433333333333333333333333333333333333332222 PP == domain 9 score: -5.4 bits; conditional E-value: 10 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLe 65 + ++ l+ +le+ ++ +++++r+ ++ ++ nk+l+d +++++L+ FUN_001065-T1 815 QNVETLERELEQKRSAVETLERQ---LQQSTQERNKVLEDKDKEISNLQ 860 45666666666666666666666...34444456666666666666654 PP == domain 10 score: 0.2 bits; conditional E-value: 0.39 Laminin_II 16 leqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseikelI 99 ++ ++ l++++++ ++ ++++ s + + v++++ l+d ++ k ++ ++ + l++l ++++ ls++++e++ + FUN_001065-T1 895 EAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDE---LSNEVQELRTVV 975 444555555555555555555555444455555555555555555555555555555554444444444...667777666655 PP == domain 11 score: 5.3 bits; conditional E-value: 0.01 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 +++ +e++++ ++ l+ + n ++ ++++ + + + e ++ +++al+ +++v +L+ ++++ ++ lk l ++ e+ FUN_001065-T1 1009 QLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEE 1089 678899*****************************************************************9999988776 PP == domain 12 score: 6.2 bits; conditional E-value: 0.0056 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++e n+++++ +e+ ++l++nl++ + ++++ ++ + ++k++d++k l + v++Le+++ ++++ ++l+ ++ ni+ +k+ FUN_001065-T1 1135 SVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENTLKEIEKSHQQLESELNE---ANGNIDGMKN 1225 6899****************************************************************9998888765544...3456665555 PP == domain 13 score: 1.7 bits; conditional E-value: 0.13 Laminin_II 2 kelaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklk 76 k+ +a+ +e ++ e++ +l+ + e++k + se+ ++++e ++++ + + l r+sv + +qL ++l FUN_001065-T1 1224 KNDIANKDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLA 1298 56677778888888999999***************************9999999999999999999999988864 PP == domain 14 score: -0.5 bits; conditional E-value: 0.61 Laminin_II 7 eanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 e t+++ ++q+ l+ ++e t ++++ +++ n +v ++++++++ +++ L ++ +L+ + +el++++e+ FUN_001065-T1 1306 ELTITLSNKEDQISSLERDVEATLQQYKDLESR---HNSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEE 1380 333445555566666666666666666666666...566666666666666666666666666666666666666555 PP == domain 15 score: -0.9 bits; conditional E-value: 0.82 Laminin_II 8 anetakevleqlaplsqnlentkeklseinrsveetnekvk....dankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++ +e ++ l +l++ le+ + l+++++s+++t+ +v + + l+d ++s ++ +qL + ++l ++ee+s+ l++n++e + FUN_001065-T1 1388 LQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLrlqsILDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNA 1481 2233333344444555556666666667777777777766523223455666777787788888888888888899999997779999998666 PP Laminin_II 98 lIa 100 +++ FUN_001065-T1 1482 IVE 1484 665 PP == domain 16 score: 7.0 bits; conditional E-value: 0.0031 Laminin_II 2 kelaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldkl 75 k++++e n ++++ ++ la++s n+ ++ e ls n++v+ n ++ + + v++L+ ++ L ++l FUN_001065-T1 1473 KANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSLS---EECFYFDSRVSELQDKVGALQEQL 1543 899***********************************888776554...555555566677766666666665 PP == domain 17 score: 6.1 bits; conditional E-value: 0.0057 Laminin_II 8 anetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseik 96 +e+++e +e +++l+ l++ ++++s++++s+ t +++d+ +l++ + ++k+a+ L + ++ ++++++ ++++e++ FUN_001065-T1 1539 LQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKS---YENAVSENENIQKELDELR 1624 4566667777777888888888888888888888888888888888888888888888888777555...3444444444888888877 PP == domain 18 score: -0.7 bits; conditional E-value: 0.75 Laminin_II 10 etakevleqlaplsqnlentkeklseinrsveetnekvk.dankalrdArrsvkkLeklapqLldklkelkqleea 84 + +++ l ql + +++l+ +e+++++++++ +e ++ ++n+ +A +v +L++++ L ++ ++l +++ FUN_001065-T1 1635 DAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQiSSNEKETLA-AKVIELQQELGLLKEQTQRLIDERDE 1709 5667788888888999999999999999999999999996666666666.57899999999999998888666665 PP == domain 19 score: -0.5 bits; conditional E-value: 0.62 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqle 82 + e ++ l l+++++++ ++ e+++++++t+++ k++ + +++ +++++++e + +++ + l +lk+ FUN_001065-T1 1686 VIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKEL 1756 33444555555666666666666666666666666666666666666666666666666666666666543 PP == domain 20 score: -5.0 bits; conditional E-value: 10 Laminin_II 15 vleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++ l ++ ++ + + +l+ ++++++ + +el++++++ s l +++s +++ FUN_001065-T1 1858 LKKGLSEMTEKQDSLTTQLNVSQKDLKRSQ-------------------------------EELEMKNNQLSTLQAEVSHLQN 1909 222222222222222222222222222222...............................3333333333333333333322 PP == domain 21 score: 3.0 bits; conditional E-value: 0.052 Laminin_II 19 laplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.lsdniseik 96 + +l+++l++ + l+ +++v e n++ + +kal+ A++ + +L + + L++ + + + ++ ++ ls+ se++ FUN_001065-T1 1935 ILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQAnLSEMASELR 2013 4589****************************************************97666666665555888888777 PP == domain 22 score: 19.2 bits; conditional E-value: 5.3e-07 Laminin_II 3 elaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.lsdn 91 ++++e + + v + +++l+ +++ +k+kl +++r+++ ++e++ +a++++ ++++k Lek L++ l+e++ +e++ + l + FUN_001065-T1 2003 ANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKdLEKT 2092 57788999999******************************************************************9999955555554 PP == domain 23 score: 6.2 bits; conditional E-value: 0.0054 Laminin_II 5 aaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdni 92 a+e+ ++++e ++ +l+q+ e +k +l+ +n+ ++e++ + ++ l+ A + L+++ +q+ + l++lk+ + s+ l + i FUN_001065-T1 2127 AEEVFSKLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETnvtlLQNRI 2218 66777788888888888888888999999999999999998888999999999999999999999999999999888777654455444444 PP == domain 24 score: -1.9 bits; conditional E-value: 1.7 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeass 86 +q+++l+ + +n+ ++l e ++++e++e + l+dA+++ +L + + + + l+++kq ++++ FUN_001065-T1 2264 SQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQE 2333 5677888888888888888888888888888899999**************************9877644 PP == domain 25 score: -2.8 bits; conditional E-value: 3.3 Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvk.dankalrdAr 58 +v e+++ ++n+ + k kl ++n++ eet ++++ ++ +a +d + FUN_001065-T1 2421 KVREKIELNKKNIAEFKVKLANANKEKEETLQELHsQLANAEKDKK 2466 5555555566778888888888888766666655533333333333 PP == domain 26 score: -1.2 bits; conditional E-value: 1 Laminin_II 5 aaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkql 81 +ae +e ++e ++ql+ sq +e++++ l +++++ + t ++++ ++ l+dA+++ k+ e + ++ l+ l++lk FUN_001065-T1 2498 IAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLE 2574 678899999******9999****************9*******************9999888888888888877754 PP == domain 27 score: -1.2 bits; conditional E-value: 1 Laminin_II 7 eanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdnis 93 ++ e+ ++v++ +a +++l ++ +++++++++ + ++k +++ + A++++ +L++ ++++ + k l+ +e+ l+++++ FUN_001065-T1 2633 SIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKRDLDEITKEKKDLERNHEQ---LKKELE 2716 56677788888888888899999999999999977777778888888999**************99887788777777...888776 PP == domain 28 score: -4.8 bits; conditional E-value: 10 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdniseikelIa 100 + e+ + +++l+ n e++k++l+e +++ + v++++ + + A r+ +L+ +++ L + ++e k e++++ l d+++++ e ++ FUN_001065-T1 2694 LDEITKEKKDLERNHEQLKKELEEQETD---FTSSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEekqlLVDQVQQLSEAVQ 2783 4567788888888888888888888888...89999999*********************999988888888877778888999998877765 PP == domain 29 score: -6.7 bits; conditional E-value: 10 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqlee 83 + + +ls + en k +e++ +++ ne+v++++ + +++ + L +++qL + +++lk++ + FUN_001065-T1 2724 SSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQTLKNKDQ 2790 4444555555555555555555555555555555555555555555555555555555555554443 PP == domain 30 score: -2.6 bits; conditional E-value: 2.7 Laminin_II 19 laplsqnlentkeklseinrsveetnekvk............dankalrdArrsvkkLeklapqLldklkelkqleea 84 l++++++l + k+ ++++++v+ +k + d++ ++ Ar++ +Lek+a +L + l e+ +++ FUN_001065-T1 2914 LKEIQAELTKAKALNEKLKAKVRVFMKKERaksesvrdvessDMKAEIDKARQEKINLEKTALELREELVEIVREKDG 2991 445555555555444444444444433333000001111122455556666666667777777777776666555555 PP == domain 31 score: 2.1 bits; conditional E-value: 0.099 Laminin_II 11 takevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 +k++++ + + q+lentk+ ++++ ++ +e++ +++ l++ + + +L+ + q + + el++l++ FUN_001065-T1 3056 LVKKIQQEKLEYVQELENTKDGYEKVLSD---KDEEIGNFKRELVSCNIETEELKGRLRQTQESFDELNKLKVD 3126 46777777777777777777777777776...566677777777777777777777777777777777776665 PP == domain 32 score: -4.4 bits; conditional E-value: 10 Laminin_II 66 klapqLldklke.lk 79 k+a +L +klke lk FUN_001065-T1 3265 KQASDLNNKLKEaLK 3279 233334444432233 PP == domain 33 score: 3.1 bits; conditional E-value: 0.05 Laminin_II 26 lentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 + k+k++ ++++ e+ n +++++ k+l+ ++v++L+ + + L + lk e+ FUN_001065-T1 3335 VAGFKSKMEMLADEKERANSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVEN 3393 6678999999****9***************************99998877777766555 PP == domain 34 score: -1.3 bits; conditional E-value: 1.1 Laminin_II 9 netakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapq 70 +e++ v e + +l+ + e+ ++++ei++ ++++ +++k +++A + ++++ ++++ FUN_001065-T1 3423 KESTDRVSELKRELESREEKHLKEIEEIKER---HDQVLIAKQKETDEAILELRQINTELQD 3481 4566666666666666666666666666666...5555568888888888888888877654 PP == domain 35 score: -0.0 bits; conditional E-value: 0.45 Laminin_II 5 aaeanetakevleqlaplsqnlent.keklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++++++ ++++ l + ++le++ ++++ i+++ ++++e+++++ + A + +++Le+ L ++++el+ + + l+ +++e ++ FUN_001065-T1 3483 LQSVSDNRDATERELIGTRAKLEQVvQDSYPVIEEKSQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTE---LKTQLEETRA 3573 56666667777777778888887752778999999************************************8888888877...8888888775 PP == domain 36 score: 5.1 bits; conditional E-value: 0.012 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklap 69 ++ ++ a+ ++ l++ ++++s++++++++tn ++ ++n+ l+ A + +++ekl + FUN_001065-T1 3601 QQQMQQLEAKFEELLSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRN 3658 4556666677777889999***************************999988888755 PP == domain 37 score: -1.9 bits; conditional E-value: 1.7 Laminin_II 13 kevleqlaplsqnlentkeklseinrsveetnekvk.dankalrdArrsvkk 63 ++ +e ++ +++le+++++ + +++v+e+ + + +++l+ +r+ + FUN_001065-T1 3679 AAAEELAHEFQVQLEKMRKSNPTTANEVDEISPPQEnKVSEMLEATQREEAN 3730 5567778888899999999988888888888765542444444444444445 PP == domain 38 score: -6.6 bits; conditional E-value: 10 Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.....lsdniseik 96 +v+++++++ + + + +++s++ +s et+ +++++++ l+ +++ kL+ ++ +++k +++k + + s l ++++i+ FUN_001065-T1 3778 NVQKVVEEVILQSS-EDNQVSSLPTS--ETEVEIENLKNELQRVKNVNEKLKAKLRTMMKK-RRVKSDSGDEDSsvrneLQTELEKIR 3861 67777777766644.45667777777..888888888888888888888888888888888.88887776655566666777777776 PP == domain 39 score: -1.8 bits; conditional E-value: 1.6 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkel 78 + e ++++++l+ +++++++k ++ n+ +e +++vk++ +l++ v+ +e+ +q + +++l FUN_001065-T1 3882 VREKESITNELKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETL 3948 3344455555555555555555555555555555555555555555555555555555544444433 PP == domain 40 score: -0.9 bits; conditional E-value: 0.82 Laminin_II 5 aaeanetakevleqlaplsqnlentkeklseinrsveetnekvk.dankalrdArrsvkkLeklapqLldklkelkqleeassslsdnisei 95 ++e n+ + + + +a l+++l+++ ek+++ r + +e + + + + +++ k+ +qL ++lk k+ +e + l++n + i FUN_001065-T1 3984 VEEYNSLLDKKDRSIAHLENQLDEVTEKYKTELRATRDQHEGIIlQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHI 4075 55566666666666667777777777776643333343343333133333333333333334566777777777777776666666664443 PP == domain 41 score: 1.8 bits; conditional E-value: 0.12 Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLekla 68 +v ++ +++++ e+++ekl ++++++++ + ++ +++ + +++v +Le+++ FUN_001065-T1 4120 NVAVDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLEREL 4174 5555566666666666666666666666666666655555555566666665554 PP == domain 42 score: 0.2 bits; conditional E-value: 0.37 Laminin_II 9 netakevleqlaplsqnlentkeklseinrsveetne 45 ne +++v ++ +++++l+++k+ ++++++++ FUN_001065-T1 4231 NEEVQKVRDDWYKMQNELDKVKAVNERLKTKLKTLMR 4267 8999*********************999999765544 PP == domain 43 score: 0.5 bits; conditional E-value: 0.32 Laminin_II 16 leqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdnisei 95 e++ + + ++ + k ++++ ++ e++n++++ + k l++ +++ L ++++ L dkl+e++q + s +n++ + FUN_001065-T1 4311 DEIVREKERRVVEHKTRMQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNLNTV 4390 56677777888899999999999999999999999999999999999999999999999999999887755544444444 PP == domain 44 score: 2.4 bits; conditional E-value: 0.079 Laminin_II 29 tkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasssl 88 +k+ + + v e +++++++ +l + +++ k+Le + +d ++ +++l+ + FUN_001065-T1 4451 LKDRYDVV---VSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTN---F 4504 33333333...445788888888888888999999999999999999999998888...3 PP == domain 45 score: -0.8 bits; conditional E-value: 0.79 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldk.lkelkql 81 + +++l++ + + +e+ ++++v +++v+d + l + ++++++Le+ +++L + +++ql FUN_001065-T1 4570 AEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEhATSMEQL 4635 567888888888888888899998889999999888888889999999998888864313445555 PP == domain 46 score: -3.0 bits; conditional E-value: 3.7 Laminin_II 30 kekls.einrsveetnekvkdanka.lrdArrsvkkLeklapqLldklkelkqleeassslsdnisei 95 +++++ ++++ v + n+++++++++ +++ ++s kk+e+l +L +k + ++ lsd+i + FUN_001065-T1 4650 RKEMQiNMDAAVMQSNKELDQMKEQyTLLKENSAKKMEQLEGELSEKRQVIE-------KLSDEIGQF 4710 2222113334444445555443333134444555555555555555533333.......466666655 PP == domain 47 score: -2.6 bits; conditional E-value: 2.8 Laminin_II 30 keklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelk 79 + l +++ +ve+ ++ ++ k + r +v L + + L+ kl+e FUN_001065-T1 4764 DQMLASLKLEVEQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETG 4813 33445556666666676677778888888888888888888888887654 PP == domain 48 score: -0.6 bits; conditional E-value: 0.69 Laminin_II 9 netakevleqlaplsqnlentkeklseinrsveetnek 46 ++++e+l+q +l+q l + ++ l +++ + e++ + FUN_001065-T1 4883 AQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHIGKG 4920 578999999**********9999999999888777665 PP >> ERM_helical Ezrin/radixin/moesin, alpha-helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.0 2.6 10 2.6e+04 66 97 .. 50 81 .. 40 85 .. 0.46 2 ? 0.1 2.3 0.45 1.1e+03 30 63 .. 116 149 .. 106 162 .. 0.57 3 ? -2.5 16.3 2.8 7e+03 24 115 .. 160 257 .. 148 261 .. 0.77 4 ? -21.8 39.1 10 2.6e+04 3 112 .. 281 387 .. 279 476 .. 0.77 5 ? -13.2 24.3 10 2.6e+04 1 113 [. 434 553 .. 434 558 .. 0.60 6 ? -8.7 28.4 10 2.6e+04 20 116 .. 516 616 .. 503 641 .. 0.63 7 ? -2.5 15.5 2.8 7.1e+03 37 98 .. 670 733 .. 666 734 .. 0.83 8 ? -7.5 33.3 10 2.6e+04 8 116 .. 732 841 .. 721 845 .. 0.80 9 ? -4.2 28.5 9.8 2.5e+04 14 116 .. 784 908 .. 782 919 .. 0.72 10 ! 5.8 14.0 0.0073 19 10 114 .. 928 1032 .. 924 1037 .. 0.94 11 ? -2.7 11.9 3.2 8.1e+03 33 111 .. 1049 1127 .. 1029 1134 .. 0.57 12 ! 18.3 9.7 1e-06 0.0026 4 113 .. 1132 1241 .. 1127 1248 .. 0.96 13 ? -1.2 3.6 1.1 2.8e+03 41 115 .. 1257 1327 .. 1245 1332 .. 0.74 14 ! 5.6 14.5 0.0089 23 24 112 .. 1345 1433 .. 1324 1440 .. 0.89 15 ? 1.7 14.2 0.14 3.7e+02 40 112 .. 1435 1517 .. 1432 1537 .. 0.55 16 ? -5.4 24.1 10 2.6e+04 10 118 .. 1538 1653 .. 1530 1655 .. 0.82 17 ! 13.5 16.7 3e-05 0.077 18 113 .. 1661 1756 .. 1654 1764 .. 0.93 18 ? -2.0 15.2 1.9 4.9e+03 23 117 .. 1817 1908 .. 1797 1913 .. 0.77 19 ? -0.6 17.1 0.71 1.8e+03 16 119 .. 1936 2039 .. 1927 2040 .. 0.91 20 ? -0.6 27.7 0.73 1.9e+03 5 117 .. 2023 2135 .. 2019 2138 .. 0.90 21 ? 1.4 22.6 0.17 4.4e+02 20 115 .. 2111 2206 .. 2104 2210 .. 0.89 22 ? -4.5 23.9 10 2.6e+04 10 119 .. 2282 2397 .. 2273 2398 .. 0.85 23 ? -11.6 28.4 10 2.6e+04 37 118 .. 2442 2531 .. 2416 2533 .. 0.61 24 ? -10.0 20.8 10 2.6e+04 18 110 .. 2550 2645 .. 2536 2648 .. 0.48 25 ? 5.0 19.1 0.014 35 22 96 .. 2645 2719 .. 2639 2727 .. 0.88 26 ! 8.2 27.7 0.0013 3.4 1 105 [. 2733 2833 .. 2733 2845 .. 0.87 27 ? -5.3 16.2 10 2.6e+04 15 99 .. 2907 2989 .. 2903 2992 .. 0.85 28 ? -2.7 13.5 3.2 8.1e+03 17 103 .. 2956 3039 .. 2954 3054 .. 0.84 29 ! 11.8 1.3 0.00011 0.28 3 97 .. 3070 3164 .. 3069 3171 .. 0.93 30 ? -11.6 15.0 10 2.6e+04 26 92 .. 3261 3328 .. 3237 3374 .. 0.45 31 ? -11.5 19.4 10 2.6e+04 25 116 .. 3407 3507 .. 3400 3511 .. 0.70 32 ? -9.9 33.7 10 2.6e+04 4 97 .. 3515 3609 .. 3514 3613 .. 0.81 33 ! 6.1 12.8 0.0061 16 3 108 .. 3603 3708 .. 3601 3716 .. 0.94 34 ? -2.2 0.3 2.3 5.9e+03 67 94 .. 3721 3748 .. 3710 3764 .. 0.45 35 ? -4.2 19.2 9.5 2.4e+04 19 113 .. 3805 3899 .. 3802 3906 .. 0.86 36 ? -10.4 16.2 10 2.6e+04 11 101 .. 3892 3982 .. 3889 4024 .. 0.54 37 ? 3.2 11.0 0.047 1.2e+02 13 108 .. 4003 4092 .. 3992 4108 .. 0.66 38 ? 5.3 12.0 0.01 27 3 54 .. 4127 4178 .. 4125 4190 .. 0.86 39 ? -8.7 23.1 10 2.6e+04 16 113 .. 4235 4331 .. 4230 4338 .. 0.68 40 ? -1.8 12.6 1.7 4.3e+03 11 91 .. 4359 4443 .. 4351 4473 .. 0.71 41 ! 12.1 2.7 8.5e-05 0.22 6 111 .. 4478 4598 .. 4474 4607 .. 0.91 42 ? -1.9 8.5 1.8 4.7e+03 37 86 .. 4605 4654 .. 4595 4663 .. 0.79 43 ? 0.1 10.7 0.44 1.1e+03 52 98 .. 4660 4706 .. 4647 4721 .. 0.85 44 ? -10.9 15.5 10 2.6e+04 6 114 .. 4750 4862 .. 4716 4868 .. 0.62 45 ? -4.7 22.9 10 2.6e+04 8 115 .. 4854 4971 .. 4848 4975 .. 0.69 Alignments for each domain: == domain 1 score: -5.0 bits; conditional E-value: 10 ERM_helical 66 rLeesaekeekekeqlerelaeaeeeiarlee 97 +L es +++e ++ ++ l+++eee+ +l+e FUN_001065-T1 50 ALSESEMRNEGINREFQKLLRQKEEELVQLRE 81 34444444444444444444444444444444 PP == domain 2 score: 0.1 bits; conditional E-value: 0.45 ERM_helical 30 eeseetaeeLeekrreaeeeaerLeqkrqeaeee 63 ++ e + Le+++ e e +rLeq+ ++ ee+ FUN_001065-T1 116 AQKDEVIGDLEKQLHESEAHVRRLEQQGCDNEEK 149 4455555556666666666666666555554443 PP == domain 3 score: -2.5 bits; conditional E-value: 2.8 ERM_helical 24 kaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeae...eekerLeesaekeekek...eqlerelaeaeeeiarleeekerkeeeaerlqeel 113 a+ + + eet+++Le++ + +e ++rL+++++ +e + +++L+ ++ + l++++++ ++++++ ++e++r e l++el FUN_001065-T1 160 AAEGFQLKLEETKQLLEDRNKTVEGLMDRLDAQKRLIEgrdQVIDQLKAMKNLDSGADelvGTLREQIEAMNARVEKSVDEARRAKREISALKKEL 255 55555667799*******************9999988833344555555555443222223689*******************************9 PP ERM_helical 114 ee 115 ee FUN_001065-T1 256 EE 257 98 PP == domain 4 score: -21.8 bits; conditional E-value: 10 ERM_helical 3 eaerekqeleerLkqyeeetkka.qeeLeeseetaeeLeekrr.eaeeeaerLeqkrqeaeeekerLee...............saekeekekeql 81 e+e+e+++ rL++y ee +ka +e e+e+ + e+ +r +++e+a+ e k ++++ k++++e + FUN_001065-T1 281 EIEKEHKQTVLRLQHYVEEKEKAlAAEFAEAEQVYKTNEHDLReRLDEKAQIIESKDEAIQVLKRAIQEknlssegssppshsdK----------- 365 89**************999999945789999999999999887357888888888887777777778775555555443333331........... PP ERM_helical 82 erelaeaeeeiarleeekerkeeeaerlqee 112 +a+lee+++++ee + l e+ FUN_001065-T1 366 ---------VMALLEEKVKEREEMIRSLSEK 387 .........3333333333333333333332 PP == domain 5 score: -13.2 bits; conditional E-value: 10 ERM_helical 1 reeaerekqeleerLk...qyeeetkkaqeeLeese...etaeeLeekrreaeeeaerL.eqkrqeaeeekerLeesaekeekekeqlerelaeae 89 +e+ e e +e e++L + ee +k+ + L++s e++e+ e++ ++ e+e+ ++q++++ ++L + + + + +++ +el ea FUN_001065-T1 434 KEKHETEMSEKEMKLSsqiKSNEELQKMVASLKDSLselESKEKVTERLLLLDAEKEQQfRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEAR 529 688888888888888622235677777777777653111444444444444444444331344445555555566677777777777777777777 PP ERM_helical 90 eeiarleeekerkeeeaerlqeel 113 +ei+ e+e++ ++ +l+ ++ FUN_001065-T1 530 AEIEAKEKEVKDLNSKIGKLKLQA 553 777777777777777766666555 PP == domain 6 score: -8.7 bits; conditional E-value: 10 ERM_helical 20 eetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqe....aeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqe 111 + k+ +eL e++ +e e++ + + + +L+ ++++ +++eke+L ++ ++ e + ++e + +++i+++eeeke e++ ++l++ FUN_001065-T1 516 DHNSKMSDELIEARAEIEAKEKEVKDLNSKIGKLKLQAKAkvtgLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQ 611 555666666666666666666666666665444433222211114555555544443333333444567777888888888888888888888888 PP ERM_helical 112 eleea 116 lee FUN_001065-T1 612 ALEEF 616 88775 PP == domain 7 score: -2.5 bits; conditional E-value: 2.8 ERM_helical 37 eeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerela..eaeeeiarleee 98 + Lee+r +e+ ++ ++r ++ ++e+Lee e e++++++ ++e+ e e ++ + ee FUN_001065-T1 670 KILEEERYCMERRLDLITKERDSFKSKVEELEEMLEAEKEQQQKKAEEISsdEDAEHAKHMAEE 733 569******************************9999999999999998622445556666655 PP == domain 8 score: -7.5 bits; conditional E-value: 10 ERM_helical 8 kqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeae.rLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerk 102 ++ l++ + ++ee + + L+ ++ L+e++++a+ ++e +L + +++ +++ +e++ + + e ++e a++++ +++le+e e+k FUN_001065-T1 732 EESLMMHVEALQEENETLRVSLDLEKSALANLKEELKQAQLNQEnELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQK 827 34678888999*****************************8775267777777777776666655555555577789******************* PP ERM_helical 103 eeeaerlqeeleea 116 + +e+l+ +l++ FUN_001065-T1 828 RSAVETLERQLQQS 841 *********99875 PP == domain 9 score: -4.2 bits; conditional E-value: 9.8 ERM_helical 14 rLkqyeeetkkaqeeLeesee.taeeLeekrreaeeeaerLeqkrqeaeeekerLee.....................saekeekekeqlerelae 87 L+q+ +e k++ +L + e +++e ++k++ +e+ ++Leqkr++ e+ ++L++ + +++ e l + e FUN_001065-T1 784 SLRQVLAEEKEKSGDLGSQLElSKQECAKKSQNVETLERELEQKRSAVETLERQLQQstqernkvledkdkeisnlqgALMENSSGFEVLNASFSE 879 566666666666666666665234566777777777777777777777777777777777777777777777777664445555555999999*** PP ERM_helical 88 aeeeiarleeekerkeeeaerlqeeleea 116 + ++ rl+e+ +ke+e+erlq+e+ e+ FUN_001065-T1 880 STIQLDRLQEQLAAKEAEVERLQKEMSEQ 908 ***********************999876 PP == domain 10 score: 5.8 bits; conditional E-value: 0.0073 ERM_helical 10 eleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerke 103 e++ L ee+ k +q ++++ ++L + e+ e ++L + e+e++ L+ + +++ + e+l + l e +++++ lee +++ke FUN_001065-T1 928 EMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDDKEAEIAHLKATTDEKDMSFEHLNTSLIESTSQLKDLEEIVQAKE 1021 788888999999999******************************************************************************* PP ERM_helical 104 eeaerlqeele 114 +e + ++ + FUN_001065-T1 1022 SELNSMRSNFD 1032 ***99987765 PP == domain 11 score: -2.7 bits; conditional E-value: 3.2 ERM_helical 33 eetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqe 111 + + L+e + e e L k +++e+ ++ L+ + e+++ + ++le a ++ e++ +e++ e++ e erl + FUN_001065-T1 1049 ATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEESMTKVRELEGNCASKDVELKAMESALEERGLENERLNK 1127 3444455555555555555666666666666666666666666666666666666666666666666666666666555 PP == domain 12 score: 18.3 bits; conditional E-value: 1e-06 ERM_helical 4 aerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarlee 97 er +e+ + L + ee+ + q++L+e+ t+e+L + + + L++ + e ++ Le + ++ ek+ +qle el ea+ i +++ FUN_001065-T1 1132 SERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMKN 1225 588899**************************************************************************************** PP ERM_helical 98 ekerkeeeaerlqeel 113 + k+ee +l e++ FUN_001065-T1 1226 DIANKDEEIVTLTEKV 1241 **********999987 PP == domain 13 score: -1.2 bits; conditional E-value: 1.1 ERM_helical 41 ekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeelee 115 e + ++ e ++L k e+e++ L+ s e++ + +ql +la ++++++l+ ke++ l+ ++e+ FUN_001065-T1 1257 EASSQMRELHDLLTLK----ETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLERDVEA 1327 4444444444444444....5777889999999999999999999999999999999999999999999988876 PP == domain 14 score: 5.6 bits; conditional E-value: 0.0089 ERM_helical 24 kaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqee 112 k +e e+e +L + +e+ a +L + +ea + +++L+ +++e+e +l++ l+e+++ ++++ + +r e+e+ rlq FUN_001065-T1 1345 KLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSI 1433 556667788888889999********************************************************************975 PP == domain 15 score: 1.7 bits; conditional E-value: 0.14 ERM_helical 40 eekrreaeeeaerLeqkrqeaeeekerLee........saekeekek..eqlerelaeaeeeiarleeekerkeeeaerlqee 112 +ek+ +ee ++ +++ +++ e +erL+ +a+ ee++ eqle +lae ++ +++l e +k +e++ l + FUN_001065-T1 1435 DEKLADLEESRMGFAENSNQLNELRERLRNkeeesnllKANVEERNAivEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMS 1517 55555555555555555555555555555533333333222222222335666666666666666666666666666555544 PP == domain 16 score: -5.4 bits; conditional E-value: 10 ERM_helical 10 eleerLkqyeeetkkaqeeLeeseetaeeLe....ekrreaeeeaerLeqkrqeaeeek...erLeesaekeekekeqlerelaeaeeeiarle 96 +l+e+L + eee++ + L+e +++ L+ + + ++e + +L+ k ++ ++k ++L++s e+ e e+ ++el+e+ +e + + FUN_001065-T1 1538 ALQEQLAEKEEEIQALESSLDERSQSISNLDtsltDTSTQLEDLRSQLASKDGKFAAMKkkaQALKKSYENAVSENENIQKELDELRKEREVFL 1631 699*********************99987761111566788888888888887766665111568889999999******************** PP ERM_helical 97 eekerkeeeaerlqeeleeare 118 eek++ e+ ++l e+ ++ + FUN_001065-T1 1632 EEKDAMEKCLTQLIEHKNQLQA 1653 *******999999988888775 PP == domain 17 score: 13.5 bits; conditional E-value: 3e-05 ERM_helical 18 yeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqe 111 +e + a e L+ s + +e L+ k e+++e +L+++ q++ +e+++L ++ +++e+ek+++e + e +e+++++e e+++ ++ + l++ FUN_001065-T1 1661 LEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKK 1754 677778899**************************************************************************99999999999 PP ERM_helical 112 el 113 el FUN_001065-T1 1755 EL 1756 87 PP == domain 18 score: -2.0 bits; conditional E-value: 1.9 ERM_helical 23 kkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeeleea 116 ++ q+ L ese+ +++L++ e e++ + + +ea e L++ ++ +++ +l ++l ++ ++r +ee e+k ++ +lq e+ FUN_001065-T1 1817 EEIQAKLIESEKCSTKLKDDF---ELEKDDWKTRLEEAACENSSLKKGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHL 1907 567788888888888888754...555555555555555555666665555566679*********************************9887 PP ERM_helical 117 r 117 + FUN_001065-T1 1908 Q 1908 6 PP == domain 19 score: -0.6 bits; conditional E-value: 0.71 ERM_helical 16 kqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerl 109 +++ + k+ q+ L+++e +eL + e ++ + + +e+ e ++Lees k +e ++l++ l e +e++r+++ek++ e+ + l FUN_001065-T1 1936 LELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMASELRRVSQEKTELESDVFDL 2029 57899999999999999999999999998888888888899999999999******************************************** PP ERM_helical 110 qeeleearee 119 +++l+ a +e FUN_001065-T1 2030 KDKLRSADRE 2039 ****999876 PP == domain 20 score: -0.6 bits; conditional E-value: 0.73 ERM_helical 5 erekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleee 98 e + +l+++L++ e + +e+L + e ++ e+ +++e+++ Le +e++++ ++L + ek+++e + + + +e e+++++l +e FUN_001065-T1 2023 ESDVFDLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKE 2116 55556799************************************************************************************99 PP ERM_helical 99 kerkeeeaerlqeeleear 117 +e+ e+ +e + + FUN_001065-T1 2117 REEDKERLSAAEEVFSKLQ 2135 9998888777776666555 PP == domain 21 score: 1.4 bits; conditional E-value: 0.17 ERM_helical 20 eetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeel 113 ee +k +ee +e aee k++e+e L+q+++ +++e+e ++ ek +l l +a e+++ l++e+e+ +e e+l++el FUN_001065-T1 2111 EELNKEREEDKERLSAAEEVFSKLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKEL 2204 56666677777778888888899999******************************************************************99 PP ERM_helical 114 ee 115 + FUN_001065-T1 2205 SD 2206 75 PP == domain 22 score: -4.5 bits; conditional E-value: 10 ERM_helical 10 eleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLee...saekeekekeqlerelaeaeeeiarleeeke 100 e +L ++ e + eL +++e+ + L+ + + + e e +q+ +e+e+e++ L++ + +++++e+ + ++l +ee++++++ +e FUN_001065-T1 2282 ETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQkhlEENSSKEERDKSDERLLFRQEELKLMQSYSE 2375 6668999****************************************************9777889999****************999986555 PP ERM_helical 101 ...rkeeeaerlqeeleearee 119 k e + +ele+a+ e FUN_001065-T1 2376 dvvTKRIEELTIAKELEKAQVE 2397 1114555555566777777765 PP == domain 23 score: -11.6 bits; conditional E-value: 10 ERM_helical 37 eeLeekrreaeeeaerLeqkrqeaeeekerLee.....saekeekek...eqlerelaeaeeeiarleeekerkeeeaerlqeeleeare 118 + +ek + ++e +L++ +++ ++++e+L+ ++ek+++ + ql++ +ae+ee +++l+++ e + + +e+l l + r+ FUN_001065-T1 2442 NANKEKEETLQELHSQLANAEKDKKAALEELKLfldnsQKEKDQALQdleLQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRD 2531 222333444444444444444444444444444555555555555555556899999999999999999999999999999999888876 PP == domain 24 score: -10.0 bits; conditional E-value: 10 ERM_helical 18 yeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqe...aeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaer 108 e+e k+++ +e+ + L+ + ++ e+e+ +++ + q +ee + + +++ + k++l++e a+++ e+a+l+ +k++++e+ FUN_001065-T1 2550 AENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEMDTRLQTsvgQEEFDKSITDRNKLISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQ 2643 4444443333333333333333333333333333333322211113333344444555666666666666666666666666666666666666 PP ERM_helical 109 lq 110 l+ FUN_001065-T1 2644 LK 2645 65 PP == domain 25 score: 5.0 bits; conditional E-value: 0.014 ERM_helical 22 tkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarle 96 + +eeL e ++ ++ L+e + + ++e Le++ + ae+e+ L++ + kek++ler +++++e+++ e FUN_001065-T1 2645 KAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKRDLDEITKEKKDLERNHEQLKKELEEQE 2719 457899******************************************999999999999998888888776654 PP == domain 26 score: 8.2 bits; conditional E-value: 0.0013 ERM_helical 1 reeaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiar 94 re+a r+ +el+ +L + ee ++++e ++e +++L ++ +++ e+ + L++k q++ rLe + + +++ek ql+++l ++ee+ + FUN_001065-T1 2733 RENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQTLKNKDQDIV----RLENELQLSQEEKLQLAEQLTSLNEELVL 2822 9*******************************************************97665....6666666677899**************** PP ERM_helical 95 leeekerkeee 105 l+++ ++ ++ FUN_001065-T1 2823 LKDAYDQLQAA 2833 *9998775544 PP == domain 27 score: -5.3 bits; conditional E-value: 10 ERM_helical 15 LkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeek 99 L++ e k+ q+eL +++ e+L+ k r+ ++ + ++ ++ e + e ++++ ek +le+ + e+ ee+ ++++ek FUN_001065-T1 2907 LHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSESVRDVESSDMKAEIDKARQ--EKINLEKTALELREELVEIVREK 2989 666777999999******************998888888888888888888888888877..99999999999999998888887 PP == domain 28 score: -2.7 bits; conditional E-value: 3.2 ERM_helical 17 qyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerke 103 +++e++ka++e e+ta eL e++ e+ +e++ ++++++++L +++++e e+ e+ lae +eei+r+ +++ ++ FUN_001065-T1 2956 DMKAEIDKARQEKINLEKTALELREELVEIVREKDGTI---GDLKQKIRQLLNEKSRNEVLVEKYEKLLAERDEEIKRIGANADVEA 3039 58999**********************99999998764...568999*******************************986655444 PP == domain 29 score: 11.8 bits; conditional E-value: 0.00011 ERM_helical 3 eaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarle 96 e e+ k+ +e+ L ee+ ++eL +eeL+ ++r+ +e ++L + + ++ + + L+ ++ +ek + ++e+ +++r++ FUN_001065-T1 3070 ELENTKDGYEKVLSDKDEEIGNFKRELVSCNIETEELKGRLRQTQESFDELNKLKVDFDHIISGLRGDLQQALEEKAVADQLAHEFRVQLERMK 3163 67999***********************************************************************999999999999998887 PP ERM_helical 97 e 97 + FUN_001065-T1 3164 S 3164 5 PP == domain 30 score: -11.6 bits; conditional E-value: 10 ERM_helical 26 qeeLeeseetaeeLeekrreaeeeaerLeq.krqeaeeekerLeesaekeekekeqlerelaeaeeei 92 q+eL+++ + ++L+e +++ + + + +++ e +++Le + + ++ +q+++ e++ + FUN_001065-T1 3261 QNELKQASDLNNKLKEALKKKRSKPRSKSSgEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFV 3328 55555555555555555555444433333202222233334444422222222222222222222222 PP == domain 31 score: -11.5 bits; conditional E-value: 10 ERM_helical 25 aqeeLeeseetaeeLeekr.reaeeeaerLeqkrqeaeeekerLee........saekeekekeqlerelaeaeeeiarleeekerkeeeaerl 109 ++eLe + ++L +++ ++ e +++Le ++++ +e+e+++e +++++++ +l++ e++ ++ +++++++ e e FUN_001065-T1 3407 ENAELENDLRYNKSLVKEStDRVSELKRELESREEKHLKEIEEIKErhdqvliaKQKETDEAILELRQINTELQDNLQSVSDNRDATERELIGT 3500 5677777777777776665146777788888888888888888888777776644444444457777777888888888888888888887777 PP ERM_helical 110 qeeleea 116 + +le++ FUN_001065-T1 3501 RAKLEQV 3507 7777665 PP == domain 32 score: -9.9 bits; conditional E-value: 10 ERM_helical 4 aerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek.eqlerelaeaeeeiarle 96 +e + q+++e L q+ee a + + e++ L+e+ +e+e + +L+ + +e ++e+++ + + +++ +ek +l++e + +++++++le FUN_001065-T1 3515 IEEKSQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRFQRSVEEKeTELREEKEGLQQQMQQLE 3608 6889999999********99999999999999999**************998877777776666666666666662358888888888888887 PP ERM_helical 97 e 97 FUN_001065-T1 3609 A 3609 5 PP == domain 33 score: 6.1 bits; conditional E-value: 0.0061 ERM_helical 3 eaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarle 96 ++++ +++ ee L q ++ + k +eeL + + ek++ a+ e++ e+ r+++ + + L+ ++ + + + e+ ++e++ ++++++ FUN_001065-T1 3603 QMQQLEAKFEELLSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRNNFDHIISGLRGDLQQAINARAAAEELAHEFQVQLEKMR 3696 566667788999********************************************************************************** PP ERM_helical 97 eekerkeeeaer 108 + + ++e+++ FUN_001065-T1 3697 KSNPTTANEVDE 3708 999999998876 PP == domain 34 score: -2.2 bits; conditional E-value: 2.3 ERM_helical 67 Leesaekeekekeqlerelaeaeeeiar 94 Le ++ +e++ + +le+ l e ++ +r FUN_001065-T1 3721 LEATQREEANLRAALEATLIERDALQNR 3748 2222333333333333333333332222 PP == domain 35 score: -4.2 bits; conditional E-value: 9.5 ERM_helical 19 eeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqee 112 e e++ ++eL++ ++ e+L+ k+r + ++++ + e +++L+ + ek +ek + e+ +e+ e+ ++++eke +e +r +e FUN_001065-T1 3805 EVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDSGDEDSSVRNELQTELEKIRQEKLEREKTCQELRLELDTFVREKESITNELKRRIDE 3898 6689999**********************99999999999999999999999999999999999999999999999998888887777765555 PP ERM_helical 113 l 113 l FUN_001065-T1 3899 L 3899 4 PP == domain 36 score: -10.4 bits; conditional E-value: 10 ERM_helical 11 leerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeeker 101 l++r+ ++ ++ +k + e+ e ++ + ++ e+ + + e++ +a + +e L++++++ +eke+l + +e e+ ++l+ e FUN_001065-T1 3892 LKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLLAEKEDLISQSKEHEKDSSELKVYYES 3982 5555555555555555555555555555555555555555555555555555555555555555555555555555555554444433333 PP == domain 37 score: 3.2 bits; conditional E-value: 0.047 ERM_helical 13 erLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeea 106 ++L ++ e+ k ++ ++++e + +++ a+ Le++r a +e+e+L+++ ++ ++e+e+ + ++++ ++ l+e+ +r e FUN_001065-T1 4003 NQLDEVTEKYKTELRATRDQHEGI------ILQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHIVSNLREDLQRALEGK 4090 444444444444444444444433......3478888999999999999999999998888888888888888888888888888777655444 PP ERM_helical 107 er 108 FUN_001065-T1 4091 AA 4092 44 PP == domain 38 score: 5.3 bits; conditional E-value: 0.01 ERM_helical 3 eaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLe 54 ++e +++elee+L ++ e+ ++++L+ +e +++Le + +e+e + e FUN_001065-T1 4127 DIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERE 4178 699************************************9888888765544 PP == domain 39 score: -8.7 bits; conditional E-value: 10 ERM_helical 16 kqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerl 109 +++ ++ k+q+eL++ + e+L+ k++ + ++++ + + +e ee +e+L + +k +ek + er ++++ + ++++eker+ e ++ FUN_001065-T1 4235 QKVRDDWYKMQNELDKVKAVNERLKTKLKTLMRKRKGGKVETSE-EENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREKERRVVEHKTR 4327 67788888999999999999999999999999888876666544.7777888777777765555555555555555666777777766555544 PP ERM_helical 110 qeel 113 +++ FUN_001065-T1 4328 MQQV 4331 4444 PP == domain 40 score: -1.8 bits; conditional E-value: 1.7 ERM_helical 11 leerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek....eqlerelaeaeee 91 l e+++++ ++ ++++ L ++ + L +++++ ++ + e++ +a e+erL e +ek ++le+el +++e FUN_001065-T1 4359 LVEQIQSLGDKLHEVEQSLAQAMSENRNLNTVLEQLQLQKVKAERELHAATGELERLLEGDRPILAEKeqriSNLEAELSDLKES 4443 6677888888888888888888888888888888888888888888888888888888866555555511234566666655554 PP == domain 41 score: 12.1 bits; conditional E-value: 8.5e-05 ERM_helical 6 rekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLee...............saekeekekeqlere 84 ek++le r k +e+ ++ ++ + L e + a e ++ e+ ++e++++ +r+e+ + +e + ++ e+e FUN_001065-T1 4478 TEKKQLESRVKAFEDGIEDINKLRTNFDHIISGLREDLHGALEGKAAAEEIANELQMKFRRFEKssvsselkvedvcigTEDMESRVLSDNEAE 4571 79*******************999999999***********************************************777777777779999** PP ERM_helical 85 laeaeeeiarleeekerkeeeaerlqe 111 +++++ +a+++eek ee++ l + FUN_001065-T1 4572 IEDLQTAVAQFREEKYDLEEQVLALDK 4598 **************9999998877765 PP == domain 42 score: -1.9 bits; conditional E-value: 1.8 ERM_helical 37 eeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerela 86 L ek +++++ e e+ ++e + +e+L + +k ke+ + ++e++ FUN_001065-T1 4605 GDLMEKQEQIQTLEEDIERLAAEHATSMEQLVLEVNKAGKERDEIRKEMQ 4654 46778888888888888888888889999999999999999988888875 PP == domain 43 score: 0.1 bits; conditional E-value: 0.44 ERM_helical 52 rLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleee 98 q +e+ ++ke+ +e+++k+ eqle el e+ + i++l++e FUN_001065-T1 4660 AVMQSNKELDQMKEQYTLLKENSAKKMEQLEGELSEKRQVIEKLSDE 4706 4567889************************************9987 PP == domain 44 score: -10.9 bits; conditional E-value: 10 ERM_helical 6 rekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek......eqlerelaeaeeeia 93 +e ++l ++Lk+ +++ a Le ++ + + Le++ + + ++ + e ++ e +++L+e+ + + ++ + +e+ e++ ei+ FUN_001065-T1 4750 KETENLRMKLKKDYDQM-LASLKLEVEQSRQQNLEKE-KFIHNQRIEVESLVRDKESLITKLRETGQVTRETLqrtdgdAADDDEIVELKNEIS 4841 56666666666655555.4555666666666666543.66677777777777777777777777444333332112222334567777777777 PP ERM_helical 94 rleeekerkeeeaerlqeele 114 +l++e + + e ++l ++ + FUN_001065-T1 4842 LLRKECQDCRVEKDKLYDKFH 4862 777777766666666666555 PP == domain 45 score: -4.7 bits; conditional E-value: 10 ERM_helical 8 kqeleerLkqyeeet.kkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLee.......saekeekekeqlerelaeaeeeia 93 k++l ++++ e k+ ++ L+e+ + a++ ee +++ e ++ L +k++++ ++k ++e+ e +eke l+++l+e +++ FUN_001065-T1 4854 KDKLYDKFHDAVESLrKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHigkgwrnDLEAARAEKELLQKQLEERTSQSV 4947 6666666666555541456888888889999999999999999999999999999999999999999988666666788888888888777655 PP ERM_helical 94 rle..eekerkeeeaerlqeelee 115 ++ e+e+ + e+l+ +l+e FUN_001065-T1 4948 TIDiaPEEEESWQTIEELRLRLHE 4971 544003333333455555555555 PP >> TSCPD TSCPD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.1 0.00041 1 15 76 .. 1717 1777 .. 1699 1794 .. 0.82 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00041 TSCPD 15 vtkgcsgkiyvtvneddgkifeVfftggcsgnllealsrlvSlaLregvpveeiieqLkgir 76 + +++++++vne ++k +V+f ++ l+ l + + l Lre ++ e+i++Lkg++ FUN_001065-T1 1717 TEA-EKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLREATDLREVIDHLKGVN 1777 333.489******999**********66666669*************************985 PP >> PRF Plethodontid receptivity factor PRF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.5 0.00022 0.56 90 160 .. 3565 3635 .. 3551 3643 .. 0.82 2 ? -3.1 0.5 2.5 6.4e+03 94 157 .. 4644 4710 .. 4635 4714 .. 0.82 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00022 PRF 90 dtfikqtdetrlknnlyfysaiveflkeamteqedlnpaelalkakfeeamansntliskisdimtqmgms 160 t +++t k+ l f ++ e e e+e l+ l akfee +++s++ isk+ + ++ m FUN_001065-T1 3565 KTQLEETRAEMRKQRLRFQRSVEEKETELREEKEGLQQQMQQLEAKFEELLSQSQASISKLEEELAHTNME 3635 45555555555678999****999999**********************************9988776665 PP == domain 2 score: -3.1 bits; conditional E-value: 2.5 PRF 94 kqtdetrlknnlyfysaiveflke..amteqedlnpaelalka.kfeeamansntliskisdimtqm 157 k+ de r + ++ + +a+++ ke m eq l + a k ++e +++ +i k+sd + q+ FUN_001065-T1 4644 KERDEIRKEMQINMDAAVMQSNKEldQMKEQYTLLKENSAKKMeQLEGELSEKRQVIEKLSDEIGQF 4710 678999999999999999999998446999999988888877526888999999*******988775 PP >> Astro_p19 Astrovirus p19 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.6 0.045 1.1e+02 106 143 .. 1662 1699 .. 1635 1708 .. 0.82 2 ? 3.2 0.6 0.029 73 111 145 .. 2794 2828 .. 2776 2850 .. 0.86 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.045 Astro_p19 106 ihkanalqerlrlsqeekatlaldvqflqhenvrlkem 143 +k +e l++s +ek tla v lq+e lke FUN_001065-T1 1662 EKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQ 1699 456677899**********************9999986 PP == domain 2 score: 3.2 bits; conditional E-value: 0.029 Astro_p19 111 alqerlrlsqeekatlaldvqflqhenvrlkemip 145 l++ l+lsqeek la ++ l+ e v lk+ FUN_001065-T1 2794 RLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYD 2828 57889*************************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (5064 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5240 (0.205128); expected 510.9 (0.02) Passed bias filter: 926 (0.0362498); expected 510.9 (0.02) Passed Vit filter: 472 (0.0184772); expected 25.5 (0.001) Passed Fwd filter: 162 (0.00634175); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 8.84u 0.52s 00:00:09.36 Elapsed: 00:00:01.27 # Mc/sec: 16160.33 // Query: FUN_001065-T2 [L=5064] Description: FUN_001065 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-07 28.7 188.2 3.3e-06 25.8 58.3 24.4 22 CCDC39 Coiled-coil domain-containing protein 39 3.4e-05 23.6 110.4 0.00031 20.4 43.9 31.4 29 Rod_CreS Crescentin, rod domain 9.6e-05 23.0 13.3 9.6e-05 23.0 13.3 41.0 38 HH_AprE AprE, long alpha-helical hairpin 0.0012 19.6 15.8 0.0012 19.6 15.8 45.0 43 ATG16 Autophagy protein 16 (ATG16) 0.0013 18.9 25.8 0.0013 18.9 25.8 37.0 37 FKBP15 FK506-binding protein 15-like domain 0.0014 19.2 8.6 0.0014 19.2 8.6 43.3 48 Laminin_II Laminin Domain II 0.0026 18.3 9.7 0.0026 18.3 9.7 47.6 45 ERM_helical Ezrin/radixin/moesin, alpha-helical domain ------ inclusion threshold ------ 0.14 12.9 0.1 1 10.2 0.1 2.6 1 TSCPD TSCPD domain 1.7 8.5 5.6 0.56 10.1 0.5 2.9 2 PRF Plethodontid receptivity factor PRF 7 6.5 6.1 73 3.2 0.6 4.2 2 Astro_p19 Astrovirus p19 protein Domain annotation for each model (and alignments): >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 16.4 0.18 4.6e+02 358 511 .. 43 200 .. 39 217 .. 0.82 2 ? -9.5 28.8 10 2.6e+04 259 400 .. 204 349 .. 185 358 .. 0.59 3 ! 5.2 14.3 0.0021 5.4 733 830 .. 367 465 .. 361 468 .. 0.92 4 ? -12.0 62.6 10 2.6e+04 202 527 .. 455 776 .. 453 781 .. 0.88 5 ! 7.1 37.7 0.00056 1.4 240 446 .. 775 985 .. 770 991 .. 0.93 6 ! 17.3 23.2 4.7e-07 0.0012 228 381 .. 1005 1158 .. 994 1159 .. 0.96 7 ! 25.8 58.3 1.3e-09 3.3e-06 228 566 .. 1131 1468 .. 1123 1468 .. 0.94 8 ! 18.2 53.7 2.5e-07 0.00064 270 558 .. 1338 1625 .. 1326 1628 .. 0.96 9 ! 19.6 60.1 9.5e-08 0.00024 217 518 .. 1453 1756 .. 1448 1757 .. 0.92 10 ? -0.0 74.7 0.08 2e+02 252 578 .. 1621 1967 .. 1612 1970 .. 0.82 11 ! 15.5 76.0 1.7e-06 0.0043 156 533 .. 1714 2097 .. 1712 2097 .. 0.91 12 ! 13.1 70.6 8.7e-06 0.022 224 585 .. 1989 2354 .. 1987 2356 .. 0.94 13 ? -18.8 93.9 10 2.6e+04 255 626 .. 2274 2647 .. 2258 2650 .. 0.88 14 ? -2.3 91.2 0.38 9.8e+02 139 509 .. 2470 2832 .. 2470 2840 .. 0.93 15 ? -0.1 29.7 0.086 2.2e+02 309 522 .. 2906 3121 .. 2873 3168 .. 0.72 16 ? -20.1 71.4 10 2.6e+04 247 604 .. 3253 3609 .. 3233 3611 .. 0.75 17 ? -13.0 55.7 10 2.6e+04 217 520 .. 3602 3908 .. 3583 3910 .. 0.57 18 ? -2.9 28.2 0.59 1.5e+03 163 327 .. 3910 4079 .. 3901 4088 .. 0.76 19 ! 9.0 22.5 0.00015 0.39 225 379 .. 4029 4187 .. 4029 4200 .. 0.88 20 ? -1.1 23.2 0.17 4.3e+02 668 766 .. 4231 4337 .. 4226 4357 .. 0.68 21 ? -0.3 50.3 0.097 2.5e+02 153 494 .. 4353 4711 .. 4346 4715 .. 0.72 22 ? -15.1 47.7 10 2.6e+04 224 482 .. 4684 4945 .. 4680 4949 .. 0.61 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.18 CCDC39 358 rakeleklleeeekrlkeldkeikklkealf.kksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvar 452 l + l e e+r++ +++e++kl + + q ++++ +e ++ + ++n ++i+ + l ++ e++ ++e q+ + e v+r FUN_001065-T2 43 TIADLRRALSESEMRNEGINREFQKLLRQKEeELVQLRENVRAGPSLSPSEFASEVQDANNPVQNIQHVQVLLAQKDEVIGDLEKQLHESEAHVRR 138 56678888999999999999999887554440444444567777788899999999**************************************** PP CCDC39 453 lkge.rseeek..eelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeel 511 l+ + r++eek +el ki+ e + ++t++lL+ k +e + +l + + + FUN_001065-T2 139 LEQQgRDNEEKvmHELAVKIRAAEGFQLKLEETKQLLEDRNKTVEGLMDRLDAQKRLIETRD 200 **********84456779**************************999999887765554444 PP == domain 2 score: -9.5 bits; conditional E-value: 10 CCDC39 259 ennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekek...kleklekklealkekl.eevkn 350 ++ k +++ + +++ + lre+ + +++++++ +e k+++s l+++le++ i+ +k +ek++ +++++ek+++++ +l ++v++ FUN_001065-T2 204 DQLKAMKNLDSGADELVGTLREQIEAMNTRVEKSVDEAGRAKREISALKKELEEKSELIASAEKLEQEKSSllmQIQEIEKEHKQTVLRLqHDVEE 299 444444444555566666777777777777777777777777777777777777665555444444444441114455544444443333135556 PP CCDC39 351 ktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelksk 400 k+ + e+e++++++e+ l+e e +++ e+ + q lk++ ++ FUN_001065-T2 300 KEKALAVEFAEAEQVYKTNEHDLRERLDEKAQIIESKDEAIQVLKRAIQE 349 66666666677777777777777777777777777766666666665554 PP == domain 3 score: 5.2 bits; conditional E-value: 0.0021 CCDC39 733 leeleeeleeleqeleeleekeeelketleekeqeleklekeieeqkeKikRadkqlkklvkeirkkketkse.leekDielrelkevnklvlqqL 827 ++ lee+++e e+ +++l+ek++ l++ +k +e++ l+k i+++ + ik + +l+ + +ei ke+ ++ + ek+++l + n+ + ++ FUN_001065-T2 367 MALLEEKVKEREEMIRSLSEKMNFLEKGSVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKHETeMSEKEMKLSSQIKSNEELQKMV 462 66799**************************************************************9988779**********999999988887 PP CCDC39 828 ael 830 a+l FUN_001065-T2 463 ASL 465 765 PP == domain 4 score: -12.0 bits; conditional E-value: 10 CCDC39 202 haeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaeleneve 297 ++e q+++ ++++ +l+ +++ ++l +e +++ r++k++ ++++k l q + + ++k+ +l + r e + e+e+++l++++ FUN_001065-T2 455 NEELQKMVASLKDSLSELESKEKVTERLLLLDAEKEQQFRDEKQAFHDSEKALHGQLQVSLDHNSKM---SDELIEARAEIEAKEKEVKDLNSKIG 547 6677888888888888888888888888888888888888888888888888888887777766655...56899999999999999999999999 PP CCDC39 298 tlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqe 393 lk q + t l+n++ ++ ke++e e +l + +++ a+++k++++++++ ae + ele+ lee + ++ k+++ ++ +++ ++ FUN_001065-T2 548 KLKLQAKAKVTGLQNEKEKL---SKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQALEEFVRSTDKRGKHTSPGRKGSLEQDED 640 99988887777777776655...59999999***************************************************************** PP CCDC39 394 lkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkge..rseeekeelekkieeLeeeldekkktqnlLq 487 + + + + + i g+ ++ + + ++ le+e ++ l + + ++ ++kv++l++ +e+++++ ++i++ e+ k +++L FUN_001065-T2 641 EQVEELDGSGTVSTIVGSSTEETGFVNVMKILEEERYCMERRLDLITKERDSFKSKVEELEEMleAEKEQQQKKAEEISSDEDAEHAKHMAEESLM 736 *********************************************************999887656666666667778888887778888889999 PP CCDC39 488 sqikkleeelrklkkkleklkeeleklkeklqelelenes 527 +++ l+ee l+ +l+ +k+ l +lke+l++ +l e+ FUN_001065-T2 737 MHVEALQEENETLRVSLDLEKSALANLKEELKQAQLNQEN 776 9*********************************999887 PP == domain 5 score: 7.1 bits; conditional E-value: 0.00056 CCDC39 240 irekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatd....lenqraeikelkkeieekekkl 331 +e ++e++ ++ l ++ke+ +l ++++ +++ +k ++ ++le el++ ++ vetl +ql++++++ le + ei++l+ + e+++ + FUN_001065-T2 775 ENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQErnkvLEDKDKEISNLQGALMENSSGF 870 56778899999*****************************************************99988733335678999*************** PP CCDC39 332 eklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleq 427 e l++++ + +l++++++ e+ ++ l+k + e+e +++l+ ++ + + + + l + ++ k +++ + a++++l++++++l + FUN_001065-T2 871 EVLNASFSESTIQLDRLQEQLAAKEAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSN 966 ************************************************************************************************ PP CCDC39 428 ellkqqellynqefqiqql 446 e+++ ++++ + e +i l FUN_001065-T2 967 EVQELRTVVDDKEAEIAHL 985 **********999999877 PP == domain 6 score: 17.3 bits; conditional E-value: 4.7e-07 CCDC39 228 klaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelk 321 +++ ++++l+e+++ k++el+ ++++++q + k+l + i+e +l+ l+e l e e+++l++++e + +l++lat+ e+ +++++el+ FUN_001065-T2 1005 ESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEESMTKVRELE 1098 567899**************************************************************************************** PP CCDC39 322 keieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeik 381 + ++k +l+++e le+ + e++++++ + e ++e+++ l+++e++ ++l+++++ FUN_001065-T2 1099 GNCASKDVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLN 1158 *****************************************************9998876 PP == domain 7 score: 25.8 bits; conditional E-value: 1.3e-09 CCDC39 228 klaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelk 321 +++ +++e++ + +k+e+ ++ +++l++ + ++l ++++ ++ kl +l++ l +e +++len ++ + k+ ++l+++l++++++i +k FUN_001065-T2 1131 ESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMK 1224 56778899999*********************************************************************************** PP CCDC39 322 keieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaai 415 ++i++k +++ l++k+ al+ +ee+k++ +a ++ +el +ll +e +l+ l++ ++ + ++ + + +l s+ ++l++ +s+ e +i FUN_001065-T2 1225 NDIANKDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQI 1318 ********************************************************************************************** PP CCDC39 416 knlkkkiakleqellkqqellynqefqiqqlerkvarlkge..rseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkklekl 507 ++l+ ++ q+++ + + + +l++ +a+ ++e +e +el + +eL+ +e +++ + Lq ++ e+el +lk +le+ FUN_001065-T2 1319 SSLERDVEATLQQYKDLE---SRHNSDVLKLKETIAEKESEnaSLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEK 1409 ***988766666655555...566688889999998888887677799********************************************** PP CCDC39 508 keeleklkeklqelelenesgekelkklkkekeellVeenllrlevkrleellnkkade 566 ++ l+++ + lq e e+ + + l+ + ++ ee + ++++l+e l++k++e FUN_001065-T2 1410 TACLKQMDDSLQRTETEVLRLQSILDEKLADLEESRMGFAENSNQLNELRERLRNKEEE 1468 *******************************************************9985 PP == domain 8 score: 18.2 bits; conditional E-value: 2.5e-07 CCDC39 270 elerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakele 363 + ++ kl+e+ +e e e a+l +ev+ l + s+l+t+ e+++a++k l++ +eke++l +l+++le+ + l++++++ +e + l+ FUN_001065-T2 1338 RHNSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQ 1431 5678999*************************************************************************************** PP CCDC39 364 klleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkge. 456 +l+e+ l+e + +++ +++l + +++l + ++++ l+a+++ a ++l++++a++ + + + +e+l + + ++++l + + ++e FUN_001065-T2 1432 SILDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSL---SEEc 1522 *************************************************************************************99...4455 PP CCDC39 457 .rseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqelelenesgekelkklkkekeellVeenll 549 + ++ el++k+ L+e+l+ek+++ + L+s++++ + + +l ++l ++ +le l+++l + +++ +k+ ++lkk++e+ + e+ + FUN_001065-T2 1523 fYFDSRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYENAVSENENI 1616 789999*******************************************************************************999888888 PP CCDC39 550 rlevkrlee 558 + e+++l++ FUN_001065-T2 1617 QKELDELRK 1625 888887776 PP == domain 9 score: 19.6 bits; conditional E-value: 9.5e-08 CCDC39 217 kqlqqrdedIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkel....eeelaelenevetlkkqlsrl 306 +ql++ e+ ++ +ee + lk++++e+++++e+ ++ l + ++n+ el+++++ +++++ +l l e+ + +++el+++v +l++ql + FUN_001065-T2 1453 NQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSLSEEcfyfDSRVSELQDKVGALQEQLAEK 1546 789999999999***********************************************98887777654444899****************** PP CCDC39 307 atdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelksk 400 ++++++ ++++ e ++i + + l+++ +le+l+ +l++ + k ++++a+ l+k +e++ +++++++ke+++l++ +++ e k++ FUN_001065-T2 1547 EEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYENAVSENENIQKELDELRK----EREVFLEEKDA 1636 **************************************************************************99986....56777788888 PP CCDC39 401 ektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkge..rseeekeelekkieeLeeeldekkktqnlLqsqikk 492 + +++ +++++ + +++ le++l e l + ++l kv +l+ e +e++++l ++ +eL ++l++ +++++ ++ ++++ FUN_001065-T2 1637 MEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQElgLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNE 1730 888888888899999999999****************9******************99999********************************* PP CCDC39 493 leeelrklkkkleklkeeleklkekl 518 e++ +++ + ++ ++ l+ lk++l FUN_001065-T2 1731 GNEKMSQVEFERNEVQSGLDHLKKEL 1756 *******9999999999999988776 PP == domain 10 score: -0.0 bits; conditional E-value: 0.08 CCDC39 252 kflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekl 345 + l +++e e + +++ +l +++++l+ +ee++ le+++ + ++l+ ++++ e+ a++ el++e+ +++ ++l +++++l +l FUN_001065-T2 1621 DELRKEREVFLEEKDAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQL 1714 344444444445555666667789999******************************************************************* PP CCDC39 346 eevknktlsaeerakeleklleeeekrlkeldkeikklkeal...fkksqelkelkskektleaeisgaea.aiknlkkkiakleqellkqqel 435 ++ + ++ ++e ++e ++ + + e +++e++ ++ lk++l +++ ++l e+ + k ++ eis+a a +++ lk++i +e+el k + FUN_001065-T2 1715 NQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELdlkLREATDLREVIDHLKGVNEEISRAAAeNAECLKTEILAKENELHKVSQS 1808 ****************9999999999999999999999986544499999999999**********99876267899***************** PP CCDC39 436 lynqefqiqqlerkv.......arlkgerseeekeelekkieeLee.......eldekkktqnlLqsqikkleeelrklkkkleklkeeleklk 515 l + ++ +++++ k+ +lk++ e ek++ + ++ee l e +++q++L++q++ ++++l++++ +le +++l++l+ FUN_001065-T2 1809 LSSNMIMLEEIQAKLiesekcsTKLKDD-FELEKDDWKTRLEEAACensslkkGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQ 1901 ************9996664443333333.2233444444444432233333339**************************************** PP CCDC39 516 eklqelelenesg...ekelkklkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLe 578 ++ +l+ ++ +++ ++l++e + + +e l+ ++k+ ++lln k+ ev +L + l+ + FUN_001065-T2 1902 AEVSHLQNVVKEEvlqSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENK 1967 **9999988887511155667799999999999999999*******************99988755 PP == domain 11 score: 15.5 bits; conditional E-value: 1.7e-06 CCDC39 156 ikeLelereklseelnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqkla.eeieelkeeirekkeele 248 +++ e+e +++++ +ne ++k+++ e +++q Ld+ +e +e +L e++ +l+ +e+I+++a e+ e lk ei k++el+ FUN_001065-T2 1714 LNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLREATDL----REVIDHLKGVNEEISRAAaENAECLKTEILAKENELH 1803 678899999*******************************************9....78************98761556679************ PP CCDC39 249 eqkkflenqkennkelekkikelerklsklreelk....eleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekkl 338 + ++ l++ +e+++k+ e e+ +kl+++ + + +++l+e e lkk ls+++++ + ++++ +k++++ +++le+ +++l FUN_001065-T2 1804 KVSQSLSSNMIMLEEIQAKLIESEKCSTKLKDDFElekdDWKTRLEEAACENSSLKKGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQL 1897 *******************************9765111155678889999999***************************************** PP CCDC39 339 ealkek...leevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqel 429 +l+++ l++v ++++ ++ ++l + +++++ + el+k++k+++ l k+ e+ el++ + + + ++ a ++i++l+ + + le+ + FUN_001065-T2 1898 STLQAEvshLQNVVKEEVLQSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESF 1991 ****86222566677899999************************************************************************* PP CCDC39 430 lkqqellynqefqiqqlerkvarlkgerseeekee..lekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqel 521 k e n++ ++ ++ + ++r++ e++e e++ l++k+++ eld k+ + ++ i+ e+++ l+k+ ++l+++le+++ k q+l FUN_001065-T2 1992 GKAVEETSNLQANLSEMASELRRVSQEKTELESDVfdLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQL 2085 ***************************9998888622679***************999999999999999999999999999999999999999 PP CCDC39 522 elenesgekelk 533 + +e++ elk FUN_001065-T2 2086 HKDLEKTNDELK 2097 888888777775 PP == domain 12 score: 13.1 bits; conditional E-value: 8.7e-06 CCDC39 224 edIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraei 317 e++ k+ ee +l+++++e +el+ ++ + + + +l+ k+++++r+l ++e+l++++e +++ +++++ l k s l++ le+++ + FUN_001065-T2 1989 ESFGKAVEETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKE 2082 778899**************************************************************************************** PP CCDC39 318 kelkkeieekekkleklekklealkekleevknktlsaeerakelekl...leeeekrlkeldkeikklkealfkksqelkelkskektleaei 408 ++l+k++e+ + +l+ + + ++ + klee++++ + +er+ +e++ l+e+e+ +l++e + lk++l +++ l+e+ ++++l++++ FUN_001065-T2 2083 QQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERLSAAEEVfskLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNL 2176 **********************************************97333678888899********************************** PP CCDC39 409 sgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeel.dekkktqnlLqsqikkleeelrklk 501 a ++++l ++ ++ ++el++ ++ l + e ++ l+++++ ++ + ++ + e i+ ++l + +++++ s k+ +++ +l+ FUN_001065-T2 2177 VAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSMEQRQGTHIPQVQEGFIAPGRNILlASVNEENSGFPSLEKQQVSQMEQLQ 2270 **********************************************9999999999999998877765155555566666666777799***** PP CCDC39 502 kkleklkeeleklkeklqelelenesgekelkklkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLeaamkeRk 585 + ++l +el ++ +kl+e+ + + el +k++ ++l V++ + e++++++ + +++e+ +L +++l+ + + +eR+ FUN_001065-T2 2271 LEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEENSSKEERD 2354 ***************************************************************************999999997 PP == domain 13 score: -18.8 bits; conditional E-value: 10 CCDC39 255 enqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleev 348 +n ++ e+ k+ e +++ +el +++e+l++l + e + ++l+++++++++q+ e+++lk++ e+++ e+ k+ e+l + ee+ FUN_001065-T2 2274 DNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEENSSKEERDKSDERLLFRQEEL 2367 444455555555555555556666789999**************************************************************99 PP CCDC39 349 k.nktlsaeerakeleklleeeekrlkeld.keikklkealfkksqelkelkskektleaeisgaeaaik.nlkkkiakleqellkqqellynq 439 k +++ s + +k +e+l ++e ++ +++ k +k+l+++ +k + +lk+k + +++ a+ k +l + +++e+ l++ ++ l n+ FUN_001065-T2 2368 KlMQSYSEDVVTKRIEELTIAKELEKAQVEeKLTKQLQDTKTHKDGVIAKLKDKVREKIELNKKNIAEFKvKLANANKEKEETLQELHSQLANA 2461 85788889999******9888887777775166899******************988776666666666626677777777778899******* PP CCDC39 440 efqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqelelenesgekelk 533 e + + ++ ++ ++e++++l++ +L + ++ek++ + Lqsq++ + + +l+ +l++l++ ++ + ++l+ l+ + +e+e k FUN_001065-T2 2462 EKDKKAALEELKLFLDNSQKEKDQALQDLELQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGK 2555 ****999999999********************************************************************************* PP CCDC39 534 klkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLeaamkeRkaEIkvhkellraekrlleeersklkaelaerkakieqlkkr 626 +++ +++e l + + l+le+++ e+ + + d+ ++ + + ++++ R++ I+ k+ l+ e+ + ++e +kl+ +ae+ a++eqlk+ FUN_001065-T2 2556 QKELKWQEALSDLQNLKLEIEKREQE-KVEMDTRLQTSVGQEEFDKSITDRNKLISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQLKAM 2647 *********************97665.7888999999999***************************************************85 PP == domain 14 score: -2.3 bits; conditional E-value: 0.38 CCDC39 139 eednealekyskeDeakikeLelereklsee....lnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqk 228 ee ++ l++ +ke ++ +++Lel+ k +e ++e +++le + t++l +Ld+ ++ r +e + L ++ ++ ++ +q++ + q+ FUN_001065-T2 2470 EELKLFLDNSQKEKDQALQDLELQLAKAIAEkeevVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQE 2563 567788999999***********999986553344888999999999*********************************************** PP CCDC39 229 laeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkk 322 + ++++lk ei+++++e e + l++ + +e +k+i+ +++ +s l+++lk ee a ++e+ l+ ++ + + ++e+ +a+ + + FUN_001065-T2 2564 ALSDLQNLKLEIEKREQEKVEMDTRLQTSVGQ-EEFDKSITDRNKLISNLKKRLK---EERAAKKDELAKLQGSIAEKDANVEQLKAMHE---E 2650 ****************************9987.69***************98765...677899**********************9998...8 PP CCDC39 323 eieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaik 416 e+ e +k+++ l++++++lk+k e ++ + ae+ +l++ l+e k++k+l+++ ++lk++l +++ ++ s + l ++ ++a + + FUN_001065-T2 2651 ELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKRDLDEITKEKKDLERNHEQLKKEL---EEQETDFTSSVDALSSQRENADRKTE 2741 999999*********************************************************97...556678999***************** PP CCDC39 417 nlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklke 509 +l+ +++ l++e+ +++ nq+ + q l +v++l++ ++ +++ + i Le+el+ ++++ +L +q+++l eel lk ++++l++ FUN_001065-T2 2742 ELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQT--LKNKDQDIVRLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYDQLQA 2832 *************************************999553..5667789**********************************9999986 PP == domain 15 score: -0.1 bits; conditional E-value: 0.086 CCDC39 309 dlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskek 402 dl ++r+e+ke+++e+++ ++ ekl++k++ +k + +++ ++e+ +++ ++++ +++ +l+k +l+e+l ++ +e + k FUN_001065-T2 2906 DLHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSESVRDVES--SDMKAEIDKARQEKINLEKTALELREELVEIVREKDGTIGDLK 2997 7888889999999999888888888888888776666655555555554..3455667777777777777777788877777776665555555 PP CCDC39 403 tleaeisgaeaaiknlkkkiakleqell.kqqellynqefqiqqlerkvarlkgerseeekeelekk...ieeLeeeldekkktqnlLqsqikk 492 + ++ +++++ + l k +kl +e + + + + n++ + q l+ +++++ +++ k+ ++k ++eLe++ d +k + +++i + FUN_001065-T2 2998 QKIRQLLNEKSRNEVLVEKYEKLLAERDeEIKRIGANADVEAQGLRDRCQHVLEDKEFLVKKIQQEKleyVQELENTKDGYEKVLSDKDEEIGN 3091 5555555555555555555555555554233456799*****************9655555555555000556666666666666666799*** PP CCDC39 493 leeelrklkkkleklkeeleklkeklqele 522 ++ el ++ ++e+lk l++++e ++el+ FUN_001065-T2 3092 FKRELVSCNIETEELKGRLRQTQESFDELN 3121 ***********************9999885 PP == domain 16 score: -20.1 bits; conditional E-value: 10 CCDC39 247 leeqkkflenqkennkelekkike.lerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeiee....kekklekle 335 ++ l+n+ ++ +l++k+ke l++k sk r++ + e+ +e+ e+e+++ +++++++ r e+ ++ +e e+ ++k+e+l FUN_001065-T2 3253 TSDYVVSLQNELKQASDLNNKLKEaLKKKRSKPRSKSSGEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFVQEKERivagFKSKMEMLA 3346 5555567889999999999998863588889999999999999999999999999999999999999999999887775542222588999999 PP CCDC39 336 kklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqel 429 ++ e+++ +ee +++ l+ + ++ l ++ +++++l+ +++ l e ++ + +++++le +++ +++ k+ ++ +l++el FUN_001065-T2 3347 DEKERANSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVENLPELKLELQ----LTVQENAELENDLRYNKSLVKESTDRVSELKREL 3436 99999999999999999999999999998888888888888888888887766544....4444556666666666666666666666677777 PP CCDC39 430 lkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeel....dekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklq 519 + +e + +i++ +v +k + ++e el++ eL+++l d + +t++ L kle+ ++ + +e+ +++ ++l ++++ FUN_001065-T2 3437 ESREEKHLKEIEEIKERHDQVLIAKQKETDEAILELRQINTELQDNLqsvsDNRDATERELIGTRAKLEQVVQDSYPVIEEKSQKIQELLSQME 3530 6666666655556667777776666677777777777777777665511115667788888888899999999999999999999999999999 PP CCDC39 520 elelenesgekelkklkkekeellVeenllrlevkrleellnkkadevfsLEkrklqLeaamkeRkaEIkvhkellraekrllee 604 e ++ ++ ++ e+ e ++e++++le++r e l + +++ ++ k++l+ + +++e + E+ +ke l+ ++++le FUN_001065-T2 3531 ENRINADNVI-----VQLERSESTLQEQVQELELSRTE-LKTQLEETRAEMRKQRLRFQRSVEEKETELREEKEGLQQQMQQLEA 3609 9999888877.....55567788888899999999865.5566677778999999999999999999999999999999988875 PP == domain 17 score: -13.0 bits; conditional E-value: 10 CCDC39 217 kqlqqrdedI....qklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrl 306 +q+qq ++++ ++++ +i +l+ee+ + + el ++ l+++ + +++ek ++ +s lr +l+++ ++ a e+ + + ql+++ FUN_001065-T2 3602 QQMQQLEAKFeellSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRNNFDHIISGLRGDLQQAINARAAAEELAHEFQVQLEKM 3695 3333333332000134455566666666666666666666666666666666666666666666666666666666655555555555555555 PP CCDC39 307 atdlenqraeikelkkeieek.ekkleklekklealkekleevknktlsaeerakeleklleeeekrlkel.dkeikklkealfkksqelkelk 398 + ++ +e+ e+ e+k ++ le+++ + ++l++ le + ++ r++ +e +l ++ +++ d + ++e + +k FUN_001065-T2 3696 RKSNPTTANEVDEISPPQENKvSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVLSTKSEKEALSsDDGNSNVNEDNVQKV------- 3782 555555555555555444444244555555555566666666666666666666666666544332222220222222333333322....... PP CCDC39 399 skektleaeisgaeaaiknl..................kkkiakleqellkqqellynq..efqiqqlerkvarlkgerseeekeelekkieeL 472 +++ + +i++l++el++ +++ ++ ++ ++ +r+v+ +g+ +++ ++el+ ++e++ FUN_001065-T2 3783 ----------------VEEVilqssednqvsslptsetEVEIENLKNELQRVKNVNEKLkaKLRTMMKKRRVKSDSGDEDSSVRNELQTELEKI 3860 ................222233334444444444433344555555555555555544400444566689999999999999999999999999 PP CCDC39 473 eeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqe 520 +e e++kt++ L +++ + e ++++l++ +el+ +ek ++ FUN_001065-T2 3861 RQEKLEREKTCQELRLELDTFVREKESITNELKRRIDELSAKNEKSNT 3908 999999999999999999999999999999999999999888887655 PP == domain 18 score: -2.9 bits; conditional E-value: 0.59 CCDC39 163 reklseelnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeirekkeeleeqkkflen 256 +e l++++++k +l + +++ +++++ d++ ++ l +e +L+ + e+ + q ++ ++d ++l +e+l ee ++ + + + + len FUN_001065-T2 3910 IEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLLAEKEDLISQSKEHEKDSSELKVYYESLVEEYNSLLDKKDRSIAHLEN 4003 8999********************************************************************9999988887777777777777 PP CCDC39 257 qkennke.....lekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieek 327 q ++ e l ++ ++ e + +++++ +le+e ++e e lk+ql++++++ e +++ + + FUN_001065-T2 4004 QLDEVTEkykteLRATRDQHEGIILQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHIVSNL 4079 7655332111003333334444456888888888888889999999999888888877766544444444444444 PP == domain 19 score: 9.0 bits; conditional E-value: 0.00015 CCDC39 225 dIqklaeeieelkeeirekkeeleeqkkflenqkennkelekk....ikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqr 314 +Iq+ a+++e+ + ++++ e+l+ q k ++n++e+ +l+++ ++ l ++l++ e ++ ++e +e++ +++ l k ++ t++en FUN_001065-T2 4029 QIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNfdhiVSNLREDLQRALEGKAAADEIAHEFQVQLKHLEKVSGNSGTQFENVA 4122 588999999999999999999999999999999999988877611114556666667777777899999************************* PP CCDC39 315 aeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldke 379 ++++ ++++ ee e+kl++++ + +++++ l+ k+++ +e + +le+ l+e e + ++ ke FUN_001065-T2 4123 VDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMKVNIGKE 4187 ********************************************************999988887 PP == domain 20 score: -1.1 bits; conditional E-value: 0.17 CCDC39 668 dakirkaEkEikaLenTLkvvnasNenyrksl.......skvdedseeleekkaLeeqlreaneklkekreeleeleeeleeleqe.leeleek 753 +++++k+ + +++n L+ v+a Ne+++++l + + +++e e++++L ++l +++++ e ++ ++l+ +l+e+ +e +++ e FUN_001065-T2 4231 NEEVQKVRDDWYKMQNELDKVKAVNERLKTKLktlmrkrKGGKVETSEEENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREkERRVVEH 4324 589*****************************66655543333344466777778888888888777777777777777776544424445555 PP CCDC39 754 eeelketleekeq 766 + ++++ l+eke+ FUN_001065-T2 4325 KTRMQQVLTEKEK 4337 5555555555554 PP == domain 21 score: -0.3 bits; conditional E-value: 0.097 CCDC39 153 eakikeLelereklseelnekkkklekevtetqslqieLdrta....eefrqlhaeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeire 242 +a i L +++ l ++l e +++l ++++e+++l ++L++ + + r+lha +L + e +l +++++I++l+ e+ +lke + FUN_001065-T2 4353 DAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNLNTVLEQLQlqkvKAERELHAATGELERLLEGDRPILAEKEQRISNLEAELSDLKESFDI 4446 566788999*******************************99733335667888888888888888888************************* PP CCDC39 243 kkeeleeqkkf.lenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenq...raeikelkkeieekekkle 332 ++++l+++ + ++q+++ ++le+++ +l+ + +l ++ k e ++++++ + +s l +dl + +a +e+ +e++ k +++e FUN_001065-T2 4447 EMRTLKDRYDVvVSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTNFDHIISGLREDLHGAlegKAAAEEIANELQMKFRRFE 4540 *****99998625788899999999999999999999999999999999999999999999999999998772224455555555555555555 PP CCDC39 333 klekkle........alkekle.evknktlsaeerakeleklleee...ekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaa 414 k + e +++ + +++++ ++e+ ++++ ee+ e++ +ldk +++ k l +k+++++ l+++ + l ae+ +++ + FUN_001065-T2 4541 KSSVSSElkvedvciGTEDMESrVLSDNEAEIEDLQTAVAQFREEKydlEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEHATSMEQ 4634 5444333333333332222211022233333333333333333322222555555666666666666666666666666666666666666666 PP CCDC39 415 iknlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkle 494 + +k k+ e+ k + n++ +++q + ++++k++++ ke+ kk+e+Le el ek++ + L+ +i +++ FUN_001065-T2 4635 LVLEVNKAGKERDEIRKE--MQINMDAAVMQSNKELDQMKEQYTL-LKENSAKKMEQLEGELSEKRQVIEKLSDEIGQFR 4711 666666666666666654..44799***************99875.4556669*******************99998876 PP == domain 22 score: -15.1 bits; conditional E-value: 10 CCDC39 224 edIqklaeeieelkeeirekkeeleeqkkflenqkennk...elekkikelerklsklreelkeleeelaelenevet.lkkqlsrlatdlenq 313 +++++l+ e+ e ++ i++ + e+ + ++ l n ++++k el+++ + le ++klr++l +++e+++l+ +++ ++l l+ ++e+ FUN_001065-T2 4684 KKMEQLEGELSEKRQVIEKLSDEIGQFRAGLVNKSDEEKlyeELQANYQLLETGNNKLRQDLYLTMKETENLRMKLKKdYDQMLASLKLEVEQS 4777 4455555566666666666666666666666555544432228889999999999999999999999999999998652566778888899999 PP CCDC39 314 raeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleae 407 r+++ e++k i++++ ++e l + e l +kl+e + t ++ +r+ ++ +e + ++e+ k++++ +k + + ++ ++ ++l+ e FUN_001065-T2 4778 RQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRTDGDAADDDEIVELKNEISLLRKECQDCRVEKDKLYDKFHDAVESLRKE 4871 9999999999999999999999999999999998888777777777665555555555555555555555555555555555555555555555 PP CCDC39 408 isgaeaaiknl.......kkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkkt 482 ++++ +++nl k+ ++l+q ll++q+ l ++ q + + + r e eke l+k++ee ++++ FUN_001065-T2 4872 LERSLHEKDNLaqkteetLKQNRELQQSLLEKQSALTKAKVQFEHIGKGW-RNDLEAARAEKELLQKQLEE-------RTSQ 4945 55555555555111111155555555555555555555555555554444.44444444555555555555.......4444 PP >> Rod_CreS Crescentin, rod domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -12.5 49.0 10 2.6e+04 7 267 .. 43 314 .. 38 341 .. 0.78 2 ? -12.4 34.0 10 2.6e+04 24 245 .. 281 509 .. 277 514 .. 0.77 3 ? -20.9 42.0 10 2.6e+04 34 266 .. 516 748 .. 508 750 .. 0.71 4 ! 8.0 39.0 0.00069 1.8 4 189 .. 756 953 .. 753 954 .. 0.86 5 ! 17.1 28.5 1.2e-06 0.0031 10 182 .. 942 1114 .. 923 1116 .. 0.80 6 ! 19.8 18.4 1.9e-07 0.00047 5 133 .. 1105 1233 .. 1101 1241 .. 0.94 7 ! 7.8 10.1 0.0008 2 88 191 .. 1230 1333 .. 1223 1342 .. 0.68 8 ! 18.2 32.1 5.5e-07 0.0014 5 171 .. 1340 1506 .. 1335 1511 .. 0.91 9 ! 20.4 43.9 1.2e-07 0.00031 2 243 .. 1421 1665 .. 1420 1668 .. 0.85 10 ? -0.8 15.7 0.34 8.7e+02 14 134 .. 1671 1787 .. 1665 1790 .. 0.79 11 ? -1.8 31.8 0.68 1.7e+03 19 220 .. 1785 1989 .. 1772 1994 .. 0.77 12 ? -1.7 30.2 0.62 1.6e+03 28 175 .. 2074 2224 .. 2071 2228 .. 0.81 13 ? -12.5 29.3 10 2.6e+04 34 208 .. 2264 2440 .. 2244 2444 .. 0.71 14 ? -11.5 34.1 10 2.6e+04 5 132 .. 2408 2542 .. 2378 2553 .. 0.59 15 ? -7.1 33.6 10 2.6e+04 8 196 .. 2505 2689 .. 2504 2692 .. 0.75 16 ? -3.1 35.4 1.7 4.3e+03 7 137 .. 2686 2816 .. 2680 2848 .. 0.80 17 ? -9.6 26.8 10 2.6e+04 1 193 [. 2907 3113 .. 2907 3166 .. 0.75 18 ? -7.8 27.2 10 2.6e+04 11 195 .. 3260 3448 .. 3246 3451 .. 0.59 19 ? -17.2 54.5 10 2.6e+04 4 221 .. 3425 3656 .. 3422 3693 .. 0.69 20 ? -10.6 41.8 10 2.6e+04 15 208 .. 3540 3749 .. 3533 3759 .. 0.64 21 ? -18.7 30.5 10 2.6e+04 9 195 .. 3686 3879 .. 3677 3887 .. 0.74 22 ! 5.0 25.3 0.0057 14 3 174 .. 3859 4024 .. 3857 4034 .. 0.88 23 ? -0.0 8.0 0.19 5e+02 75 174 .. 4031 4130 .. 4028 4131 .. 0.92 24 ? 3.6 7.2 0.016 40 6 65 .. 4123 4182 .. 4118 4193 .. 0.89 25 ? -4.3 21.9 4 1e+04 7 128 .. 4247 4364 .. 4241 4369 .. 0.87 26 ! 4.5 27.7 0.0082 21 5 181 .. 4318 4499 .. 4315 4508 .. 0.80 27 ? 1.2 25.4 0.083 2.1e+02 24 211 .. 4510 4703 .. 4494 4705 .. 0.87 28 ? -11.6 21.2 10 2.6e+04 13 169 .. 4670 4823 .. 4656 4828 .. 0.72 29 ? -5.1 21.8 6.8 1.7e+04 27 162 .. 4831 4960 .. 4821 4985 .. 0.68 Alignments for each domain: == domain 1 score: -12.5 bits; conditional E-value: 10 Rod_CreS 7 rllelealleqetaasdklrrevagltrrlsaaereleelsa.....rlakleaalkeaeaakee...lrielrektalaealErqlkaeteqnra 94 +++l++ l++ ++ ++re ++l+r+ + +l e + ++++++++a+ +++ ++ l++k + +lE+ql + + + r FUN_001065-T2 43 TIADLRRALSESEMRNEGINREFQKLLRQKEEELVQLRENVRagpslSPSEFASEVQDANNPVQNiqhVQVLLAQKDEVIGDLEKQLHESEAHVRR 138 578999999999999999999999999888776665555443111114568889999998766551116799************************ PP Rod_CreS 95 leeelkaLraea.kaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearla..eletaldaerarlralegqLaaeqaererae 187 le++ + ++++ + + ++ +aeg +++e ++lle+ n+ l++ a+ e r + + +a+++ + ++l g L ++ ++ + + FUN_001065-T2 139 LEQQGRDNEEKVmHELAVKIRAAEGFQLKLEETKQLLEDRNKTVEGLMDRLDAQKRLIETRDQviDQLKAMKNLDSGADELVGTLREQIEAMNTRV 234 ***9998888761567899******************************998876666666551155556666778889999******99999999 PP Rod_CreS 188 aqleeevealraEraslamklealsaRaaateqlltqaRnqLrerdeairaaEralkeasieratlerrlegleadlarq 267 +++ +e+ +++ E+++l+ +le+ s a++e+l ++ L +e ++ + ++ + +e+ l+ a+++++ FUN_001065-T2 235 EKSVDEAGRAKREISALKKELEEKSELIASAEKLEQEKSSLLMQIQEIEKEHKQTVLRLQHDVEEKEKALAVEFAEAEQV 314 99999********************************9999998888887777777777777766666666555554433 PP == domain 2 score: -12.4 bits; conditional E-value: 10 Rod_CreS 24 klrrevagltrrlsa.aereleelsarlakleaalkeaeaakeel...rielrektalaealErqlkaeteqnraleeelkaLraeakaaekalqe 115 ++ +e++++ rl +e++ ++l+ + a++e+ k +e + e+ ++++ e + +a ++ +++ +e++ + + + ++ ++ ++ e+++ e FUN_001065-T2 281 EIEKEHKQTVLRLQHdVEEKEKALAVEFAEAEQVYKTNEHDLRERldeKAQIIESKDEAIQVLKRAIQEKNLSSEGSSPPSHSDKVMALLEEKVKE 376 44455555555554313333333444444444444444443333211133444444455555566666666666667777899999999******* PP Rod_CreS 116 aegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaqleeevealraEraslamkleal 211 e+++++++e+ + le+ + + ++ + + +++ + l ++l+a+ + ++ + + e +e+e + + + +++e l+ asl+ l++l FUN_001065-T2 377 REEMIRSLSEKMNFLEKGSVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKHETEMSEKEMKLSSQIKSNEELQKMVASLKDSLSEL 472 ************************************************************************************************ PP Rod_CreS 212 saRaaateqll...tqaRnqLrerdeairaaEralke 245 + + te+ll ++ +q r+ +a++ +E+al + FUN_001065-T2 473 ESKEKVTERLLlldAEKEQQFRDEKQAFHDSEKALHG 509 *********9955568889999999*******99875 PP == domain 3 score: -20.9 bits; conditional E-value: 10 Rod_CreS 34 rrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraeakaaekalqeaegelatarerlal 129 ++ s++++el e+ a++++ e+++k+ + + +l+++ + a++ l+ + ++ +++ ++le l + r+e a k++++ e+e + a+ ++ FUN_001065-T2 516 DHNSKMSDELIEARAEIEAKEKEVKDLNSKIGKLKLQAK---AKVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTE 608 566889999999999999999999999988888887655...555666666667777789999999999999999999999999999999999999 PP Rod_CreS 130 leqEnrrLqalveeqaaelaelearlaeletaldaerarlra..legqLaaeqaere...raeaqleeevealraEraslamklealsaRaaateq 220 leq + + + +++ + + + r le+ d++ + l+ + + ++ +e + +++ leee ++ ++ + ++ + + +e FUN_001065-T2 609 LEQALEEFVRSTDKRGKHTSP--GRKGSLEQDEDEQVEELDGsgTVSTIVGSSTEETgfvNVMKILEEERYCMERRLDLITKERDSFKSKVEELEE 702 999999999999999998774..4556666666666655532112222222222222111333333333333333333344444455666777899 PP Rod_CreS 221 lltqaRnqLrerdeairaaEralkeasieratlerrlegleadlar 266 +l ++q++ ++e+i + E a ++ ++l+ +e+l+++++ FUN_001065-T2 703 MLEAEKEQQQKKAEEISSDEDAEHAKHMAEESLMMHVEALQEENET 748 9999999999999999999999999999999999999999999876 PP == domain 4 score: 8.0 bits; conditional E-value: 0.00069 Rod_CreS 4 akvrllelealleqet.aasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 +k++l++l++ l+q + +++++l e+++l++ l++ +++ +l ++l+ ++++ ++ +++e l el++k++++e+lErql++ t+++ ++ e+ FUN_001065-T2 756 EKSALANLKEELKQAQlNQENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQERNKVLED 851 6899999999999876256789***************************************************************99887777665 PP Rod_CreS 99 lk........aL...raeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaer 183 ++ aL ++ +++ +++ +e+ +l++++e+la e+E +rLq+ + eq a +l+ + +++ + + l++ e L a q+ + FUN_001065-T2 852 KDkeisnlqgALmenSSGFEVLNASFSESTIQLDRLQEQLAAKEAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHT 947 5412221111222223456788999*****************************************999999999999999999999999999999 PP Rod_CreS 184 eraeaq 189 ++ a+ FUN_001065-T2 948 DKQTAE 953 998876 PP == domain 5 score: 17.1 bits; conditional E-value: 1.2e-06 Rod_CreS 10 elealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLr 103 +++ + ta+ ++lr +++l++++ ++ +++ a++a+l+a e++ +e l +l e t+++++lE +a + + +++++ + FUN_001065-T2 942 AVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDDKEAEIAHLKATTDEKDMSFEHLNTSLIESTSQLKDLEEIVQAKESELNSMRSNFDEQA 1035 4677777888888888888888888888888888888888888888888888888888888888888888888888888888888888888888 PP Rod_CreS 104 aeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqae 182 + k + ++e l+ ++e+l e+E + L + e+q a l +l+ r +e t++++ ++ +++L a++++ FUN_001065-T2 1036 NSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEESMTKVRELEGNCASKDVELKAMESA 1114 8888888888888888999999999999999999999999999999999998888888887777777777777776665 PP == domain 6 score: 19.8 bits; conditional E-value: 1.9e-07 Rod_CreS 5 kvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 v+l +e+ le+ +++ l+++ a+ +r ++++++ l++ ++ ++l+a+l+e++a+ e+l ++ + + a++ +l++ l a +e ++le+ FUN_001065-T2 1105 DVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENT 1198 578888999************************************************************************************* PP Rod_CreS 99 lkaLraeakaaekalqeaegelatarerlalleqE 133 lk ++ ++ e++l ea+g+++ +++ a ++E FUN_001065-T2 1199 LKEIEKSHQQLESELNEANGNIDGMKNDIANKDEE 1233 **********************9998887766666 PP == domain 7 score: 7.8 bits; conditional E-value: 0.0008 Rod_CreS 88 eteqnraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqa 181 +e++ +l+e + aL + ++ +ea ++++++++ l l e E + L+ ve+q+ +l++rla +++l++ +l++ e q+++ + FUN_001065-T2 1230 KDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLER 1323 5666777777777777777777777777777777777777777777777777777777777777777777777777777777777777776665 PP Rod_CreS 182 ereraeaqle 191 e+ +q++ FUN_001065-T2 1324 DVEATLQQYK 1333 5555555554 PP == domain 8 score: 18.2 bits; conditional E-value: 5.5e-07 Rod_CreS 5 kvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 ++ +l l++ ++ ++++l ev++l r+s+++ + ee+ a l++l++ +e+e + el+++l+ekta +++++ l+ + + l++ FUN_001065-T2 1340 NSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSI 1433 57789999999**********************************************************************9888888778877 PP Rod_CreS 99 lkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlra 171 l+ + a ++ + +e ++l+++rerl e+E++ L+a vee a + +le+rlae++ + + +++l+a FUN_001065-T2 1434 LDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSA 1506 7777777777777789999*****************************************9999888877765 PP == domain 9 score: 20.4 bits; conditional E-value: 1.2e-07 Rod_CreS 2 pkakvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnral 95 ++++ ++l l+++l + a ++ r a+ +++l+++ ++l + ++ + l+a+++e++a +e+l ++l+e + + +l l a n+++ FUN_001065-T2 1421 QRTETEVLRLQSILDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAK---NKEV 1511 677788888888888888888888888888888888888888888888888888888888888888888888888888888888765...4555 PP Rod_CreS 96 eeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaq 189 + + L++e +++++e++ + ++e+la e+E ++L + +e + +++l+ l +++t+l++ r++l++ +g++aa++ ++++ ++ FUN_001065-T2 1512 DSLNMSLSEECFYFDSRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKS 1605 5556778889999999999*************************************************************************99 PP Rod_CreS 190 lee...evealraEraslamklealsaRaaateqlltqa...RnqLrerdeairaaEral 243 +e+ e+e + E l+ + e a+e+ ltq+ +nqL+ ++e+++ E++l FUN_001065-T2 1606 YENavsENENIQKELDELRKEREVFLEEKDAMEKCLTQLiehKNQLQAKNEEVQGLEKKL 1665 99822245677899999****99999999*****99875333899999999999999875 PP == domain 10 score: -0.8 bits; conditional E-value: 0.34 Rod_CreS 14 lleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraeak 107 +l+ ++++++l ++v +l+++l+ ++++ ++l + ++l ++l+++ea+k+++ ++++e + ++ ++E + ++ + +l++el+ + ea FUN_001065-T2 1671 SLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLREA- 1763 566667788888888889999999999999999999999999999999999999999999999999999888888888888888877666555. PP Rod_CreS 108 aaekalqeaegelatarerlalleqEn 134 ++l e++ +l+ ++e+ ++++En FUN_001065-T2 1764 ---TDLREVIDHLKGVNEEISRAAAEN 1787 ...467788888888888888877777 PP == domain 11 score: -1.8 bits; conditional E-value: 0.68 Rod_CreS 19 taasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelr....ielrektalaealErqlkaeteqnraleeelkaLraeaka 108 ++++ l++e+ + +++l ++++ l+ + l++++a+l e e+ + +l+ +e ++ ++++e++ + ++ +++e ++ L +++++ FUN_001065-T2 1785 AENAECLKTEILAKENELHKVSQSLSSNMIMLEEIQAKLIESEKCSTKLKddfeLEKDDWKTRLEEAACENSSLKKGLSEMTEKQDSLTTQLNV 1878 4566779999999999**************************99887776332256667777777777777777788889999*********** PP Rod_CreS 109 aekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaererae.aqleeevealraEr 201 + k+l ++++el+ ++++l l++E Lq++v e + + + e +e a++ + +l++qL ++q + +e + e ++ +l+ + FUN_001065-T2 1879 SQKDLKRSQEELEMKNNQLSTLQAEVSHLQNVVKEEVLQSQKGETLTDE----IHAKKLEILELQKQLKQQQHLLNDKEgEVTELNNLSLENKK 1968 ***********************************99997766555444....45556666688888888777644444044455555555555 PP Rod_CreS 202 a..slamklealsaRaaateq 220 a ++ ++e+ls R +a+e FUN_001065-T2 1969 AlnFANTRIEELSERGNALEE 1989 422578999999999999986 PP == domain 12 score: -1.7 bits; conditional E-value: 0.62 Rod_CreS 28 evagltrrlsaaereleelsarlakleaalkeaeaakeelrielr...ektalaealErqlkaeteqnraleeelkaLraeakaaekalqeaeg 118 ++++++r+ ++ ++le++ +l+ +++ ke+e + eel e + e+ ++ae++ +l++ + al++e++ L++e++ ++ lqe FUN_001065-T2 2074 SLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREedkERLSAAEEVFSKLQEMESFYGALKQEKESLKTELEDVNNVLQEITT 2167 6677888888888899999999999999999999888887555440004555555666677777777889999999999999999999999999 PP Rod_CreS 119 elatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegq 175 e +++ +l + + + L + e++ ael +l+ l++ et + ++r++++e++ FUN_001065-T2 2168 EKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSMEQR 2224 999999999999999999999999999999999999999999999999999999986 PP == domain 13 score: -12.5 bits; conditional E-value: 10 Rod_CreS 34 rrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraeakaaekalqe...aegelatar 124 +++ +++ e+++l+a+l++ ++l+e + k el + + ++++l q + t + +++++e + ++e++ ++ e + +e+++ FUN_001065-T2 2264 SQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEensSKEERDKSD 2357 4556677788889999999999999888888888899999999999999999999999999999888888887766555433132667788888 PP Rod_CreS 125 erlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaqleeevealraEraslamkl 208 erl ++E + +q+ +e+++ + e ++ele+a +e + +++l+ ++ ++ + + e++e + +a + kl FUN_001065-T2 2358 ERLLFRQEELKLMQSYSEDVVTKRIEELTIAKELEKAQVEE-KLTKQLQDTKTHKDGVIAKLKDKVREKIELNKKNIAEFKVKL 2440 88888888888889999998877666666677887765443.334455555566666666666666666666666666666666 PP == domain 14 score: -11.5 bits; conditional E-value: 10 Rod_CreS 5 kvrllelealleqetaasdklr.revagltrrlsaaereleelsarla.kleaalkeaeaakeelrielr....ektalaealErqlkaeteqn 92 k + ++ a+l+ + ++ +l+ +++a+ + +l++a++e+ee++++l+ +l++a k++ aa eel++ l+ ek +++++lE ql+++ ++ FUN_001065-T2 2408 KTHKDGVIAKLKDKVREKIELNkKNIAEFKVKLANANKEKEETLQELHsQLANAEKDKKAALEELKLFLDnsqkEKDQALQDLELQLAKAIAEK 2501 4444444455555555555543145666666777777777766666652455555666666677766553222255666667777776666555 PP Rod_CreS 93 raleeel.kaLraeakaaekalqeaegelatarerlalleq 132 +++ +el ++L+ + +++e+ +++++ ++++r + le FUN_001065-T2 2502 EEVVQELqSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEG 2542 55555531456666666666666666666666555444444 PP == domain 15 score: -7.1 bits; conditional E-value: 10 Rod_CreS 8 llelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelka 101 ++el++ le ++ ++l + +++l+++ +ele l +l ++e++ k++e + +e+ ++l++ ++++e+ E++ + + + ++ ++ + FUN_001065-T2 2505 VQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEMDTRLQTSVGQ-EE 2597 5788999999999999999999999999988999999999999999999999999999988888888888888877766666666554333.33 PP Rod_CreS 102 LraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqaereraeaqleeeve 195 ++ + +k ++++ + ++e++a ++E +Lq + e a++ +l+a ++e + ++ ++l++ ++ L +++++ er ++ +e+e+ FUN_001065-T2 2598 FDKSITDRNKLISNLKKR---LKEERAAKKDELAKLQGSIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMI 2688 444555555555555544...4566677788888888888888888888888888888888888888888888888888888888888888876 PP Rod_CreS 196 a 196 FUN_001065-T2 2689 N 2689 5 PP == domain 16 score: -3.1 bits; conditional E-value: 1.7 Rod_CreS 7 rllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelk 100 ++++l++ l ++t++++ l r++++l+++l + e +++ + +++l+++ ++a++++eel+++l+ + ++ + r+ +++e+++ l +++ FUN_001065-T2 2686 EMINLKRDLDEITKEKKDLERNHEQLKKELEEQETDFT---SSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQ 2776 789*************************9998888776...5578999999******************************************* PP Rod_CreS 101 aLrae...akaaekalqeaegelatare.rlalleqEnrrL 137 +L++ +k +++++ ++e+el+ +e +l+l+eq + L FUN_001065-T2 2777 QLSEAvqtLKNKDQDIVRLENELQLSQEeKLQLAEQ-LTSL 2816 **9761115679***********9666515666665.4444 PP == domain 17 score: -9.6 bits; conditional E-value: 10 Rod_CreS 1 lpkakvrllelealleqetaasdklrrevagltrr...lsaaerel..eelsarlakleaalkeaeaakeelriel....rektalaealE... 82 l k++++l e++a l++ a ++kl+++v+ ++ s++ r++ ++ a+++k+ ++ + e+++ elr el rek + +l FUN_001065-T2 2907 LHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKeraKSESVRDVesSDMKAEIDKARQEKINLEKTALELREELveivREKDGTIGDLKqki 3000 578999*********************9997654411144444444114567788888888888888888888776444477888888776555 PP Rod_CreS 83 rqlkaeteqnraleeelkaLraeakaaekal.qeaegelatarerla.lleqEnrrLqalveeqaaelaelearlaeletaldaerarlraleg 174 rql +e+ +n+ l e ++L ae + k++ ++a+ e + +r+r + +le+ + +++ e + ele + + e+ l ++ + + + FUN_001065-T2 3001 RQLLNEKSRNEVLVEKYEKLLAERDEEIKRIgANADVEAQGLRDRCQhVLEDKEFLVKKIQQEKLEYVQELENTKDGYEKVLSDKDEEIGNFKR 3094 89999*******999999988888877777746688888888888651556666666888888999999************************* PP Rod_CreS 175 qLaaeqaereraeaqleee 193 +L++ + e+e + l + FUN_001065-T2 3095 ELVSCNIETEELKGRLRQT 3113 ***9998888776655444 PP == domain 18 score: -7.8 bits; conditional E-value: 10 Rod_CreS 11 lealleqetaasdklrrevaglt.rrlsaaereleelsarlakleaalkeaeaakeelrielr.ektalaealErqlkaeteqnraleeelkaL 102 l++ l+q + ++kl++ +++ + + +s++++e e + + +a+le ++ a +++++ ++lr e +++ Er + + + + l+ e+++ FUN_001065-T2 3260 LQNELKQASDLNNKLKEALKKKRsKPRSKSSGEHEMSNETIAELE-VIRAAKVESDKQMAHLRlELDNFVQEKERIVAGFKSKMEMLADEKERA 3352 344444444444444444433321335677777766666666555.244444444444444443334455666666666677788888999999 PP Rod_CreS 103 raeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelear...laeletaldaerarlralegqLaaeqaereraeaqleee 193 + + +ek+l + + ++++ + +ll En +L++ ve+ el+ + +aele+ l+ +++ +++ + ++ + e e e+++ +e FUN_001065-T2 3353 NSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVENLPELKLELQLTvqeNAELENDLRYNKSLVKESTDRVSELKRELESREEKHLKE 3446 9999999999999999999999999999999999998888665544444444000555666666666666666666666666666555555555 PP Rod_CreS 194 ve 195 +e FUN_001065-T2 3447 IE 3448 54 PP == domain 19 score: -17.2 bits; conditional E-value: 10 Rod_CreS 4 akvrllelealleqetaasdklrrevagltrr.lsaaereleelsarlakleaalkeaeaakeelr.ielrektalaealErqlkae....teq 91 + r++el++ le +++ k +e+++ ++ l a ++e +e+ +l++++++l+++ + ++ r +++re +++lE+ ++ +e+ FUN_001065-T2 3425 STDRVSELKRELESREEKHLKEIEEIKERHDQvLIAKQKETDEAILELRQINTELQDNLQSVSDNRdATERELIGTRAKLEQVVQDSypviEEK 3518 5668888988888877777776667666665524556677788888888777777776555544442455555555555555444432222677 PP Rod_CreS 92 nraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelear....laeletaldae....rarlralegqLa 177 +++++e l+++++ a++ + ++e+ t++e+ + le + L+ ee ae+ + r ++e et l++e ++++++le+++ FUN_001065-T2 3519 SQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRfqrsVEEKETELREEkeglQQQMQQLEAKFE 3612 8888888888888888888888888888888888888888889999999999999987754441111566666665542222789999999999 PP Rod_CreS 178 aeqaereraeaqleeevealraEraslamklealsaRaaateql 221 + ++ +++ ++leee++ E s ++kl ++ + + e+l FUN_001065-T2 3613 ELLSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKL 3656 99999999999999999999999999999999999877777766 PP == domain 20 score: -10.6 bits; conditional E-value: 10 Rod_CreS 15 leqetaasdklrrevagltrrlsaaereleelsarlak....leaalkeaeaakeelrielrektalaea.lErqlkaeteqnraleeelkaLr 103 q ++ +l+++v++l+ + +++ +lee+ a+++k ++++++e+e++ e + l+++ +++ea E l + + + +leeel++ FUN_001065-T2 3540 IVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKqrlrFQRSVEEKETELREEKEGLQQQMQQLEAkFEELLSQSQASISKLEEELAHTN 3633 5555666667777777777777777777776666655322226788888888888888888888877775367777777778888888888888 PP Rod_CreS 104 aeakaaekalqeaegelatarerl....alleqEnrrLqalveeqaa......el.aelearlaeletaldaerarlralegqLaaeqaerera 186 e+ + +++lq a+ge ++ ++ + +++ Lq++++ aa e ++le + + t++++ + + +e + +++ ++++r FUN_001065-T2 3634 MELVSFNEKLQTADGEKQDIEKLRnnfdHIISGLRGDLQQAINARAAaeelahEFqVQLEKMRKSNPTTANEVDEISPPQENKVSEMLEATQRE 3727 8888888888888877666544431111344444445555544433211000033123333333444444444444556799************ PP Rod_CreS 187 eaqleeevealraEraslamkl 208 ea+l +++ea Er +l+ +l FUN_001065-T2 3728 EANLRAALEATLIERDALQNRL 3749 ******************9998 PP == domain 21 score: -18.7 bits; conditional E-value: 10 Rod_CreS 9 lelealleqetaasdklrrevagltr.rlsaaereleelsarlakleaalkeaeaakeelrielrektalae.alErqlkaeteqnraleeelk 100 e + le+ ++++ + +ev++++ + +++++ le+++ + a+l aal+ + + ++l+ +lr+ ++ + + E+++ ++ n +++e++ FUN_001065-T2 3686 HEFQVQLEKMRKSNPTTANEVDEISPpQENKVSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVLStKSEKEALSSDDGNSNVNEDNV 3779 5888999999*************99636677777777777888899999999999999999999999887652689999999999999999987 PP Rod_CreS 101 aLrae..akaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLa...aeqaereraeaq 189 ++ e ++ ++ q + + + + + l++E +r +++ e+ a+l + + + + d++++ ++l+++L +e+ ere+ ++ FUN_001065-T2 3780 QKVVEevILQSSEDNQVSSLPTSETEVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDSGDEDSSVRNELQTELEkirQEKLEREKTCQE 3873 6655411333344444444444555556677999**************9999988888888888887777778887775111566666666666 PP Rod_CreS 190 leeeve 195 l e+ FUN_001065-T2 3874 LRLELD 3879 665555 PP == domain 22 score: 5.0 bits; conditional E-value: 0.0057 Rod_CreS 3 kakvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnrale 96 k + ++le e+ ++ + + d+ re +++t ++++r+++elsa+++k+++ +++ ea++++ +l e ++ +E +++ ++ ++l+ FUN_001065-T2 3859 KIRQEKLEREKTCQELRLELDTFVREKESIT---NELKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLR 3949 5566677777777777777777777777776...67899******************************************************* PP Rod_CreS 97 eelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarlraleg 174 e++ L ae +e ++++ ++ ++ +e + +e + ++l ++ +a+le +l+e ++ ++e++++r++ FUN_001065-T2 3950 HENADLLAE---KEDLISQSKEHEKDSSELKVYYESLVEEYNSLLDKKDRSIAHLENQLDEVTEKYKTELRATRDQHE 4024 *****9665...78999999999999999999*********************************9999999987644 PP == domain 23 score: -0.0 bits; conditional E-value: 0.19 Rod_CreS 75 talaealErqlkaeteqnraleeelkaLraeakaaekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerar 168 +++a +lE++ +++++++l+++lk ++e + k + ++ ++re+l+++ + + + +++ e+ ++l +le + + t+ ++ FUN_001065-T2 4031 QSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHIVSNLREDLQRALEGKAAADEIAHEFQVQLKHLEKVSGNSGTQFENVAVD 4124 6899*************************************************************************99998888888877777 PP Rod_CreS 169 lraleg 174 ++++e+ FUN_001065-T2 4125 TSDIET 4130 777665 PP == domain 24 score: 3.6 bits; conditional E-value: 0.016 Rod_CreS 6 vrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaake 65 v +++e+ e+ ++ d++++e+a+++++l ++++++l +++a+le++l+e+e+ k FUN_001065-T2 4123 VDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMKV 4182 6678899999999******************************************99775 PP == domain 25 score: -4.3 bits; conditional E-value: 4 Rod_CreS 7 rllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelk 100 +l ++a++e+ + ++l r+ +g + + s+ e++ eel +lak+ ++ e+e+a+++lri+l+e +++ Er+ + + + +++ e++ FUN_001065-T2 4247 ELDKVKAVNERLKTKLKTLMRKRKGGKVETSEEENR-EELHTELAKVRQEKLETERAAQQLRIDLDE---IVREKERRVVEHKTRMQQVLTEKE 4336 556678888888888888888888888888886665.8899999999999999**********9998...578889****************** PP Rod_CreS 101 aLraeakaaekalqeaegelatarerla 128 + + ++++ek l e ++++ ++ e+ + FUN_001065-T2 4337 KVNNLLETKEKLLLERDAAISSLVEQIQ 4364 ********************99999876 PP == domain 26 score: 4.5 bits; conditional E-value: 0.0082 Rod_CreS 5 kvrllelealleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleee 98 + r++e ++ ++q +++k+++ ++ ++ l + + ++ l+++++ l ++l+e e+ +++ +e r+ ++ +e+l+ q +++++ a ++e FUN_001065-T2 4318 ERRVVEHKTRMQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNLNTVLEQLQLQKVKAERELHAATGE 4411 5689999999999999999999999988888888888888888888888888888888888888888888888888887777777777777777 PP Rod_CreS 99 lkaL....raeakaaekalqeaegelatarerlalle.qEnrrLqalveeqaaelaelearlaeletaldaerarlralegqLaaeqa 181 l++L r ++ +e++++++e+el +++e ++ + r +v eq ++++le++l l t ++ +r++a e + + + FUN_001065-T2 4412 LERLlegdRPILAEKEQRISNLEAELSDLKESFDIEMrTLKDRYDVVVSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINK 4499 777744445568899*****************99843033456666777999**************************9987766555 PP == domain 27 score: 1.2 bits; conditional E-value: 0.083 Rod_CreS 24 klrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektal.aealErqlkaeteqnraleeelkaLraeakaaekalqea 116 lr+++ g ++ +aae+ +el+ + +++e++ + e ++e i ++ +++ + + E++ ++ + +++ee+ L++++ a +k +q+ FUN_001065-T2 4510 GLREDLHGALEGKAAAEEIANELQMKFRRFEKSSVSSELKVEDVCIGTEDMESRvLSDNEAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDG 4603 599*****************************************99999887762578999999999999999999999999999999999999 PP Rod_CreS 117 egelatarerlalleqEnrrLqa....lveeqaaelaelearlaeletaldae.rarlralegqLaaeqaereraeaqleeevealraErasla 205 g+l +++e+ + le++ +rL a +e+ + e+++ + +e + ++ + a++ + +++L +++++ + ++++ +++e+l+ E + + FUN_001065-T2 4604 KGDLMEKQEQIQTLEEDIERLAAehatSMEQLVLEVNKAGKERDEIRKEMQINmDAAVMQSNKELDQMKEQYTLLKENSAKKMEQLEGELSEKR 4697 99999999999999999999976333369**************999888875515778899999999999999999999999999999998877 PP Rod_CreS 206 mkleal 211 +e l FUN_001065-T2 4698 QVIEKL 4703 777766 PP == domain 28 score: -11.6 bits; conditional E-value: 10 Rod_CreS 13 alleqetaasdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkaeteqnraleeelkaLraea 106 ++ eq t +++ +++++l+ +ls+ + +e+ls +++++ a l ++ ++e ++ +e +a+ + lE++ ++ ++ +e + Lr ++ FUN_001065-T2 4670 QMKEQYTLLKENSAKKMEQLEGELSEKRQVIEKLSDEIGQFRAGLVNK---SDEEKL-YEELQANYQLLETGNNKLRQDLYLTMKETENLRMKL 4759 333333333333334566777788888888888888888888887765...344444.4678888899999999999999999999999**999 PP Rod_CreS 107 ka.aekalqeaegelatarerlalleqEnrrLqalveeqaaelaelearlaeletaldaerarl 169 k +++ l+ + e ++ r++ e+ + +++ ve+ + +l +l+e+ + ++++++r+ FUN_001065-T2 4760 KKdYDQMLASLKLEVEQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRT 4823 7537888988888888777776555555577888888999999999999999999999999997 PP == domain 29 score: -5.1 bits; conditional E-value: 6.8 Rod_CreS 27 revagltrrlsaaereleelsarlakleaalkea.eaakeelrielrektalaealErqlkaeteqnraleeelkaLraeakaaekalqeaege 119 +e+ +l++++s + +e+++ + +kl ++ ++a e +el +l ek la++ E lk+++e +++l e ++aL + + e+ ++ FUN_001065-T2 4831 DEIVELKNEISLLRKECQDCRVEKDKLYDKFHDAvESLRKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHIGKGWRND 4924 688899*************************998577789**********************************99986655555544444444 PP Rod_CreS 120 latarerlalleqEnrrLqalveeqaaelaelearlaeletal 162 l + + +E++ Lq+ ee + + + +e e+ FUN_001065-T2 4925 L-------EAARAEKELLQKQLEERTSQSVTIDIAPEEEESWQ 4960 4.......44444444444444444444444444333333322 PP >> HH_AprE AprE, long alpha-helical hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.6 2.1 10 2.6e+04 141 177 .. 43 75 .. 40 85 .. 0.59 2 ? -2.7 3.4 3 7.5e+03 128 175 .. 115 162 .. 106 178 .. 0.66 3 ? -16.4 29.6 10 2.6e+04 8 188 .. 125 311 .. 122 335 .. 0.63 4 ? 1.2 4.5 0.18 4.7e+02 64 126 .. 411 474 .. 398 481 .. 0.77 5 ? -1.6 19.6 1.4 3.5e+03 46 179 .. 488 614 .. 477 622 .. 0.71 6 ? -5.1 19.7 10 2.6e+04 47 174 .. 668 792 .. 659 807 .. 0.73 7 ? -8.1 21.3 10 2.6e+04 24 171 .. 741 838 .. 738 880 .. 0.56 8 ? 0.5 23.2 0.32 8.1e+02 3 176 .. 882 1078 .. 880 1084 .. 0.66 9 ? 0.3 17.5 0.35 8.8e+02 4 186 .. 967 1158 .. 966 1163 .. 0.77 10 ? 2.1 8.7 0.099 2.5e+02 63 166 .. 1137 1237 .. 1109 1268 .. 0.62 11 ? 1.0 16.4 0.22 5.6e+02 51 180 .. 1272 1401 .. 1249 1411 .. 0.77 12 ? -3.5 7.7 5.3 1.3e+04 116 189 .. 1394 1466 .. 1379 1468 .. 0.59 13 ! 23.0 13.3 3.8e-08 9.6e-05 53 186 .. 1467 1593 .. 1465 1598 .. 0.87 14 ? -4.9 19.8 10 2.6e+04 64 187 .. 1594 1716 .. 1591 1720 .. 0.79 15 ? -1.2 4.3 1 2.6e+03 120 185 .. 1713 1780 .. 1711 1851 .. 0.66 16 ? -3.8 18.6 6.6 1.7e+04 60 164 .. 1860 1964 .. 1836 1990 .. 0.52 17 ? 2.0 21.1 0.11 2.7e+02 54 190 .. 1997 2129 .. 1966 2130 .. 0.86 18 ! 5.6 4.8 0.0084 21 47 108 .. 2161 2222 .. 2138 2225 .. 0.85 19 ! 6.5 9.9 0.0045 12 82 169 .. 2262 2349 .. 2249 2369 .. 0.84 20 ? -1.5 1.4 1.3 3.2e+03 142 181 .. 2426 2468 .. 2418 2478 .. 0.48 21 ? -7.1 21.0 10 2.6e+04 63 165 .. 2485 2584 .. 2471 2595 .. 0.78 22 ? -1.7 24.9 1.5 3.8e+03 34 187 .. 2598 2756 .. 2585 2760 .. 0.84 23 ? -6.6 15.9 10 2.6e+04 52 113 .. 2765 2829 .. 2755 2834 .. 0.84 24 ? -0.0 7.7 0.44 1.1e+03 92 170 .. 2909 2989 .. 2901 3008 .. 0.82 25 ? -2.6 7.3 2.8 7.1e+03 21 164 .. 3019 3167 .. 3013 3173 .. 0.86 26 ? -3.2 6.3 4.3 1.1e+04 49 164 .. 3256 3371 .. 3235 3376 .. 0.80 27 ? -4.8 21.5 10 2.6e+04 51 190 .. 3397 3538 .. 3371 3539 .. 0.90 28 ! 6.6 19.1 0.0041 10 119 189 .. 3538 3608 .. 3536 3610 .. 0.96 29 ? -9.1 11.5 10 2.6e+04 69 112 .. 3615 3658 .. 3609 3738 .. 0.59 30 ? -3.7 12.2 6 1.5e+04 62 163 .. 3850 3952 .. 3845 3959 .. 0.90 31 ? -1.7 8.1 1.5 3.8e+03 6 115 .. 3939 4048 .. 3934 4070 .. 0.78 32 ! 5.5 3.5 0.009 23 55 108 .. 4125 4178 .. 4091 4181 .. 0.85 33 ? -4.0 7.8 7.4 1.9e+04 133 172 .. 4280 4319 .. 4275 4338 .. 0.71 34 ? 3.7 0.3 0.032 81 22 105 .. 4433 4516 .. 4422 4520 .. 0.66 35 ? -3.3 15.8 4.6 1.2e+04 80 187 .. 4569 4677 .. 4565 4685 .. 0.51 36 ? -0.1 9.0 0.46 1.2e+03 31 114 .. 4654 4737 .. 4648 4747 .. 0.75 37 ? -4.6 9.9 10 2.6e+04 63 181 .. 4761 4879 .. 4748 4889 .. 0.89 38 ? -1.7 6.5 1.4 3.6e+03 61 106 .. 4896 4941 .. 4879 4945 .. 0.82 Alignments for each domain: == domain 1 score: -4.6 bits; conditional E-value: 10 HH_AprE 141 eiararqqiaeaelqiaqlraeyreeaaeeLrevqae 177 ia +r++++e e + + +++e+++ + r+ ++e FUN_001065-T2 43 TIADLRRALSESEMRNEGINREFQKLL----RQKEEE 75 577777777777777777777776643....333333 PP == domain 2 score: -2.7 bits; conditional E-value: 3 HH_AprE 128 laelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevq 175 la+ + i++l+ ++ ++++ + +e+q +++ + e+a ++r ++ FUN_001065-T2 115 LAQKDEVIGDLEKQLHESEAHVRRLEQQGRDNEEKVMHELAVKIRAAE 162 455555677777777777777777777777777777777777766665 PP == domain 3 score: -16.4 bits; conditional E-value: 10 HH_AprE 8 lraqlaallaqeaRLqAErdgadtiefPaellaaaadpevaeliaaqrqlfearraalagelailqeq...ieqleeeieglraql...aalreql 97 l++ql + +a + RL+ + +++++ + ++ ++ +a + ++ ++ +ql+e r ++++g + l++q ie ++ i++l+a++ ++++e + FUN_001065-T2 125 LEKQLHESEAHVRRLEQQGRDNEEKVMHELAVKIRAAEGFQLKLEETKQLLEDRNKTVEGLMDRLDAQkrlIETRDQVIDQLKAMKnldSGADELV 220 667777777777777655555555555443334444666666677778888888887777555444442225555555555555551115666666 PP HH_AprE 98 alleeelaglreLlekGlvpktrllelerelaelegqiaelr...aeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraa 188 l+e+++++ + +ek + + +re+++l+ +++e + a+ ++++q+ + + qi+++++e+++++ + ++v+++ l + + a FUN_001065-T2 221 GTLREQIEAMNTRVEKSV---DEAGRAKREISALKKELEEKSeliASAEKLEQEKSSLLMQIQEIEKEHKQTVLRLQHDVEEKEKALAVEFAEA 311 667777777777777754...5566667777777777765540004445556777777888888888888888888888877766665555554 PP == domain 4 score: 1.2 bits; conditional E-value: 0.18 HH_AprE 64 alagelailqeqieqleeeieglraqlaalreqlal.leeelaglreLlekGlvpktrlleler 126 a+ +++lqe+++ ++ei+g++++ ++ ++ + l+ ++++++eL + k l ele FUN_001065-T2 411 DKASTIKVLQETLQAKDQEIAGIKEKHETEMSEKEMkLSSQIKSNEELQKMVASLKDSLSELES 474 5567889999999999999999999998877666544888999999998887777777777776 PP == domain 5 score: -1.6 bits; conditional E-value: 1.4 HH_AprE 46 evaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelrae 141 e +++ ++++q f+ +al g+l++ + ++ + e+ ++ra+++a++++++ l+ + +l+ l +k ++ l+ e l+ +++el+ FUN_001065-T2 488 EKEQQFRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEARAEIEAKEKEVKDLNSKIGKLK------LQAKAKVTGLQNEKEKLSKEMQELEMH 577 447999**************************************************9998886......444455555555555555555555555 PP HH_AprE 142 iararqqiaeaelqiaqlraeyreeaaeeLrevqaela 179 + r++ ++ +i q+++e +e a+++ e+++ l+ FUN_001065-T2 578 LLHEREEKLAIQKKISQIEEE-KEGAETKRTELEQALE 614 555555555555555555544.3444444444444444 PP == domain 6 score: -5.1 bits; conditional E-value: 10 HH_AprE 47 vaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraei 142 v ++++ +r +e r + + +e++ ++++e+lee +e+ ++q + + e+++ +e+ + + ++e+ l+ + +l+ e l+ +++ ++++ FUN_001065-T2 668 VMKILEEERYCMERRLDLITKERDSFKSKVEELEEMLEAEKEQQQKKAEEIS-SDEDAEHAKHMAEESLMMHVE--ALQEENETLRVSLDLEKSAL 760 5578888888888888888888888888888888888888888887777775.488888888888888887655..56666667777777778889 PP HH_AprE 143 ararqqiaeaelqiaqlraeyreeaaeeLrev 174 a +++++++a+l+ ++ ++ + +++ L+e FUN_001065-T2 761 ANLKEELKQAQLNQENELHSEMDSLRQVLAEE 792 99998888888877666555555555555554 PP == domain 7 score: -8.1 bits; conditional E-value: 10 HH_AprE 24 AErdgadtiefPaellaaa..a.dpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlv 116 A ++ ++t+++ +l+++a + +e++++ +q++ +++ ++l++ la +e+ l +++e +++ a + ++++ le+el+++r+ +e FUN_001065-T2 741 ALQEENETLRVSLDLEKSAlaNlKEELKQAQLNQENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVE---- 832 44444455555433333332234444445555555555555555555555555555555555555555555555555555555555555443.... PP HH_AprE 117 pktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeL 171 +++++L FUN_001065-T2 833 -------------------------------------------------TLERQL 838 .................................................333333 PP == domain 8 score: 0.5 bits; conditional E-value: 0.32 HH_AprE 3 aelealraqlaallaqeaRLqAErdgadt....ief.........P..aellaaaadpevaeliaa.......qrqlfearraalagelailqe 74 +l++l++qlaa +a+++RLq E++ +++ ++ + lla++ ++ ++ ++++ + + +++r+++l++e++ l++ FUN_001065-T2 882 IQLDRLQEQLAAKEAEVERLQKEMSEQEAgheqLKLsytgvcatvSemQLLLADK-EETLK-AVQThtdkqtaELNSLRSRHDELSNEVQELRT 973 589******************9999775555456664454444431333333333.22222.22222344444677788899999999999999 PP HH_AprE 75 qieqleeeieglraqlaalreqlalle....eelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyr 164 ++ e+ei+ l+a+ + ++ + + l+ e ++l++L e +++++l ++ + e +++ +l++ i++ +++ +++++ + ++e + FUN_001065-T2 974 VVDDKEAEIAHLKATTDEKDMSFEHLNtsliESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDE-V 1066 99999999999999888888877776622224456677777777778888888888888888888888888888888888888777766655.4 PP HH_AprE 165 eeaaeeLrevqa 176 +++ ++L+ +a FUN_001065-T2 1067 TDLTSKLENQEA 1078 455555555555 PP == domain 9 score: 0.3 bits; conditional E-value: 0.35 HH_AprE 4 elealraqlaallaqeaRLqAErdgadtief...Paellaaaa.dpevaeliaaqrqlfearraalagelai...lqeqieqleeeieglraql 90 e+++lr+ ++ +a+ a L A d + ++ f l ++++ ++++e+++a ++ +++ r++++++ + l++ i++ +++gl++ l FUN_001065-T2 967 EVQELRTVVDDKEAEIAHLKATTDEK-DMSFehlNTSLIESTSqLKDLEEIVQAKESELNSMRSNFDEQANSykdLTQVISENATRLQGLQEAL 1059 68999999****************55.6777545467777776689999*****9999999999999988872225688999999********* PP HH_AprE 91 aalreqlal....leeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelae 180 a++ ++ le + a+l++L+ + + t+++ele + a+ + ++ ++++++++ + + ++ a+ ++ ++e ++ L++ +++ + FUN_001065-T2 1060 VAKEDEVTDltskLENQEASLKDLATRCEESMTKVRELEGNCASKDVELKAMESALEERGLENERLNKSSAESER-SVNEMNDSLAKKEEKYNA 1152 ***999875111145566678899999999999999999999999999999999998765555544444444333.367888888888888888 PP HH_AprE 181 leerlr 186 l+ +l+ FUN_001065-T2 1153 LQANLN 1158 887776 PP == domain 10 score: 2.1 bits; conditional E-value: 0.099 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqi 156 ++++ +la +e+ l++ +++ +a+++ l + + ++ l++l++Ll +++ + le +l e+e + ++l++e+++a+ i +++ i FUN_001065-T2 1137 NEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLL---IAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMKNDI 1227 4555556666666666666666666666666666666666666666665...555555566666666666666666666666666666666666 PP HH_AprE 157 aqlraeyree 166 a+ ++e ++ FUN_001065-T2 1228 ANKDEEIVTL 1237 6666555443 PP == domain 11 score: 1.0 bits; conditional E-value: 0.22 HH_AprE 51 iaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlek.Glvpktrllelerelaelegqiaelraeia 143 +++ +++++ ++ ++ ++l++++++ ++++++l +l++++ q+++le++++++ + ++ ++++l l+ ++ae e++ a+l +e++ FUN_001065-T2 1272 KETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLERDVEATLQQYKDlESRHNSDVLKLKETIAEKESENASLCSEVK 1365 45588899999999999*************************************98766555415556789**********************9 PP HH_AprE 144 rarqqiaeaelqiaqlraeyreeaaeeLrevqaelae 180 ++ + +e++ + ++++a+ ++ +++ +e + el e FUN_001065-T2 1366 ELVFRASELNTRNEEANAS-LKALQDVFNEKENELFE 1401 9999999999888777654.34455555555555555 PP == domain 12 score: -3.5 bits; conditional E-value: 5.3 HH_AprE 116 vpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraar 189 ++++l el+ +l e + + +++ +++r++ ++ +++ +++ + + +ee + +e + +l+el+erlr+ + FUN_001065-T2 1394 EKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSILDE-KLADLEESRMGFAENSNQLNELRERLRNKE 1466 4556666666666666666666666666666666665543333.334455666667777888888888887765 PP == domain 13 score: 23.0 bits; conditional E-value: 3.8e-08 HH_AprE 53 aqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiarar 146 +++l++a+ +++++ +++l++++++ ++ ++l+++l+a+++++++l+ +L e+ ++ +r+ el+ ++ +l+ q+ae + ei+ ++ FUN_001065-T2 1467 EESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNM------SLSEECFYFDSRVSELQDKVGALQEQLAEKEEEIQALE 1554 57788888888888888888888888888888888888888888888874......799*********************************** PP HH_AprE 147 qqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlr 186 +++ e + i +l+++ +++++++L++++++la+ + + FUN_001065-T2 1555 SSLDERSQSISNLDTS-LTDTSTQLEDLRSQLASKDGKFA 1593 ************9876.79*************98776665 PP == domain 14 score: -4.9 bits; conditional E-value: 10 HH_AprE 64 alagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqia 157 a++++ ++l+++ e + +e e+++++l+ lr++++ + ee +++++ l + + k++l + e+ le +++ ++ +++ + ++ + + ++++ FUN_001065-T2 1594 AMKKKAQALKKSYENAVSENENIQKELDELRKEREVFLEEKDAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVI 1687 78899999**************************************************************999999988888888888777777 PP HH_AprE 158 qlraeyreeaaeeLrevqaelaeleerlra 187 +l++e + e+ + + e +el +l++ FUN_001065-T2 1688 ELQQEL-GLLKEQTQRLIDERDELHSQLNQ 1716 777663.34444444444444444444443 PP == domain 15 score: -1.2 bits; conditional E-value: 1 HH_AprE 120 rllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreea..aeeLrevqaelaeleerl 185 +l + e e ++e +++e + ++++++ +++e+++ ++ l++e ++ a++Lrev l ++e++ FUN_001065-T2 1713 QLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLreATDLREVIDHLKGVNEEI 1780 45555555555555555555555555555555555555544443332211344555555555444444 PP == domain 16 score: -3.8 bits; conditional E-value: 6.6 HH_AprE 60 arraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeae 153 + +++ ++++ l++q+ ++ ++ +++l+ ++ ql+ l++e++ l+ +++ + ++ l e+ + + +i el+ ++++ + +++ e FUN_001065-T2 1860 KGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHLQNVVKEEVLQSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKE 1953 4445555555555555555555555555555555555555555555555555555555555555555555555555555555555555555555 PP HH_AprE 154 lqiaqlraeyr 164 ++++l++ + FUN_001065-T2 1954 GEVTELNNLSL 1964 55555444333 PP == domain 17 score: 2.0 bits; conditional E-value: 0.11 HH_AprE 54 qrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpkt.rllelerelaelegqiaelraeiarar 146 +++ ++a+ +++a+el ++ ++le+ + l+ +l++++++l+ ++e+l++ +G++ ++ ++ le++++ le++++e++ + ++++ FUN_001065-T2 1997 ETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLTNAS----EGITTRNeQIKSLEKDRSHLESSLEEMQRKEQQLH 2086 6777899999*****************************************9965....6666666155689********************** PP HH_AprE 147 qqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraard 190 + +++++ +++ ++ +e +++L+e+++e +e +erl aa++ FUN_001065-T2 2087 KDLEKTNDELKYM-DDLCKERESKLEELNKEREEDKERLSAAEE 2129 ***9999998766.5678888999***************99986 PP == domain 18 score: 5.6 bits; conditional E-value: 0.0084 HH_AprE 47 vaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglr 108 v + i+++++ ++++ a ++l+ l+++ eq+++e+e+l+++l+ +++++ ll+ +++++ FUN_001065-T2 2161 VLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSME 2222 4456777899999999999999*********************************9999987 PP == domain 19 score: 6.5 bits; conditional E-value: 0.0045 HH_AprE 82 eieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaae 169 +++++++ ++ +a l e +++l e e lv t+ll+ + +l +l+ q + +++e++ ++q+ +e e ++a+l+++++ee ++ FUN_001065-T2 2262 QVSQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQKHLEENSS 2349 44444444444445556688999***********************************************************998664 PP == domain 20 score: -1.5 bits; conditional E-value: 1.3 HH_AprE 142 iararqqiaeaelqiaqlra...eyreeaaeeLrevqaelael 181 i+ ++ iae++ ++a++++ e ++e+ ++L+ ++++ + FUN_001065-T2 2426 IELNKKNIAEFKVKLANANKekeETLQELHSQLANAEKDKKAA 2468 4445555555555555544300033344444444444433333 PP == domain 21 score: -7.1 bits; conditional E-value: 10 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqi 156 +al+ +l + i++ ee +++l++ql+ + + + l++ l +L +++ v +l l+r+l ++e++ + + + ++a + ++ ++l+i FUN_001065-T2 2485 QALQDLELQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAA---LDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEI 2575 34444444566677777777777777777666666666554...456678999***************************************** PP HH_AprE 157 aqlraeyre 165 +++++e +e FUN_001065-T2 2576 EKREQEKVE 2584 ***999765 PP == domain 22 score: -1.7 bits; conditional E-value: 1.5 HH_AprE 34 fPaellaaaa.dpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGl.vpktrllele 125 f + ++ +++ ++++ ++ +r+ + a+l+g++a ++++eql++ e+ ++ + + l+ ++ l+++re le+ +++ +++ l+ FUN_001065-T2 2598 FDKSITDRNKlISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMsIAEDEMINLK 2691 56666677766777788899999999999999999999999999999999999999999999999999999999999999876489999***** PP HH_AprE 126 relaelegqiaelraeiararqqiaeaelqiaq...lraeyreeaaeeLrevqaelaeleerlra 187 r+l e+ + +l+ + ++++++++e e + + ++ re+a+++ +e+q +l+ l+e++ FUN_001065-T2 2692 RDLDEITKEKKDLERNHEQLKKELEEQETDFTSsvdALSSQRENADRKTEELQLQLDALNEEVSE 2756 **************************999877611155678999999999999999999998765 PP == domain 23 score: -6.6 bits; conditional E-value: 10 HH_AprE 52 aaqrqlfearraalagelailq...eqieqleeeieglraqlaalreqlalleeelaglreLlek 113 + ++ql+ + ++l++ ++ l+ + i +le+e++ ++++ l eql +l+eel l++ +++ FUN_001065-T2 2765 QEEKQLLVDQVQQLSEAVQTLKnkdQDIVRLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYDQ 2829 458889999999999999999622267999**************************999887765 PP == domain 24 score: -0.0 bits; conditional E-value: 0.44 HH_AprE 92 alreqlalleeelaglreLlekGlvpktrllelerelaelegqi..aelraeiararqqiaeaelqiaqlraeyreeaaee 170 +r +l+ +++el++ ++L ek ++ + er+ +e ++ ++++aei +arq+ +e +lr+e +e ++e+ FUN_001065-T2 2909 KTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSESVRDVesSDMKAEIDKARQEKINLEKTALELREELVEIVREK 2989 5677888899**************************9998655411789***********999999999999988877765 PP == domain 25 score: -2.6 bits; conditional E-value: 2.8 HH_AprE 21 RLqAErdga.dtiefPaellaaaadpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlek 113 L+AErd + + i a+++a+ + + + ++++ + l ++ +++ + ++ l+++ ++ e+ ++ ++++ + +++l + + e + l++ l + FUN_001065-T2 3019 KLLAERDEEiKRIGANADVEAQGLRDRCQHVLEDKEFLVKKIQQEKLEYVQELENTKDGYEKVLSDKDEEIGNFKRELVSCNIETEELKGRLRQ 3112 69999997766688899998777799999*************************************************9999999999999999 PP HH_AprE 114 Glvpktrllelere....laelegqiaelraeiararqqiaeaelqiaqlraeyr 164 + +l l+ + ++ l+g+++++ e a a q e++ q+++ +++y FUN_001065-T2 3113 TQESFDELNKLKVDfdhiISGLRGDLQQALEEKAVADQLAHEFRVQLERMKSSYA 3167 9999999988876522226789999999999999999999999999999888876 PP == domain 26 score: -3.2 bits; conditional E-value: 4.3 HH_AprE 49 eliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraei 142 +++ q++l +a + + + a+ +++ + ++ +++ ++ e + ++ +++ ++++ l + + e er +a +++++ l e FUN_001065-T2 3256 YVVSLQNELKQASDLNNKLKEALKKKRSKPRSKSSGEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFVQEKERIVAGFKSKMEMLADEK 3349 67777888888887777777777777777778888888888888888888888899999999999999999999999999999*********** PP HH_AprE 143 ararqqiaeaelqiaqlraeyr 164 +ra++ i+e+e q+ +++ r FUN_001065-T2 3350 ERANSLIEEYEKQLLTKDTAVR 3371 ********99999998877765 PP == domain 27 score: -4.8 bits; conditional E-value: 10 HH_AprE 51 iaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelagl..reLlekGlvpktrllelerelaelegqiaelraei 142 ++ + ql + a+l+++l ++ +++ + ++++l+++l++ +e ee++ + L +k+ +lel++ +el+ ++++ + + FUN_001065-T2 3397 LKLELQLTVQENAELENDLRYNKSLVKESTDRVSELKRELESREEKHLKEIEEIKERhdQVLIAKQKETDEAILELRQINTELQDNLQSVSDNR 3490 5668899999999******************************999988888888762256********************************* PP HH_AprE 143 ararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraard 190 +++++ ++++++q+ ++ ++e+ +++q+ l+++ee++++a++ FUN_001065-T2 3491 DATERELIGTRAKLEQVVQDSYPVIEEKSQKIQELLSQMEENRINADN 3538 *****************************************9998875 PP == domain 28 score: 6.6 bits; conditional E-value: 0.0041 HH_AprE 119 trllelerelaelegqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLrevqaelaeleerlraar 189 + +++ler+ + l+ q++el+ + ++++ q++e+++++ + r +++ ++e+ e+++e + l++++++++ FUN_001065-T2 3538 NVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRFQRSVEEKETELREEKEGLQQQMQQLE 3608 6789***************************************************************9986 PP == domain 29 score: -9.1 bits; conditional E-value: 10 HH_AprE 69 lailqeqieqleeeieglraqlaalreqlalleeelaglreLle 112 l++ q++i++leee++ + +l + +e l+ ++ e +++++L + FUN_001065-T2 3615 LSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRN 3658 56667777777777777777777777777777777777766654 PP == domain 30 score: -3.7 bits; conditional E-value: 6 HH_AprE 62 raalagelailqeqieqleeeieglraqlaalreqlalleeela.glreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeael 154 r++l++el+ ++++ + e+ ++lr +l++ ++ +++ el+ ++ eL +k+ ++t + +le ++ + +gq+ el ++ +++ +a + FUN_001065-T2 3850 RNELQTELEKIRQEKLEREKTCQELRLELDTFVREKESITNELKrRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQ 3943 899************************************999973589*****************************99999999999999988 PP HH_AprE 155 qiaqlraey 163 +++ lr+e FUN_001065-T2 3944 NVETLRHEN 3952 888888876 PP == domain 31 score: -1.7 bits; conditional E-value: 1.5 HH_AprE 6 ealraqlaallaqeaRLqAErdgadtiefPaellaaa.a.dpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreql 97 +++++ + +l+ + a L+AE +++ i +e ++++ + ++ l++ ++l++++ +++a ++l+e e+ + e+++ r q ++ q+ FUN_001065-T2 3939 DQAWQNVETLRHENADLLAEKEDL--ISQSKEHEKDSsElKVYYESLVEEYNSLLDKKDRSIAHLENQLDEVTEKYKTELRATRDQHEGIILQI 4030 677888888888888899998855..55555555555134555669999999999999999999999999999999999999999999999999 PP HH_AprE 98 alleeelaglreLlekGl 115 ++ ++ l++ r L+ k FUN_001065-T2 4031 QSHADNLEKERLLASKET 4048 999999999988888765 PP == domain 32 score: 5.5 bits; conditional E-value: 0.009 HH_AprE 55 rqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglr 108 ++ e+r ++l+++l++ q++++ ++ ++ +++ +++l+ ++a+le+el + FUN_001065-T2 4125 TSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERE 4178 555799*******************************************98766 PP == domain 33 score: -4.0 bits; conditional E-value: 7.4 HH_AprE 133 gqiaelraeiararqqiaeaelqiaqlraeyreeaaeeLr 172 +++el +e+a++rq+ e+e + +qlr + e ++e+ r FUN_001065-T2 4280 ENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREKER 4319 5677888888888888888888888888777666666544 PP == domain 34 score: 3.7 bits; conditional E-value: 0.032 HH_AprE 22 LqAErdgadt.iefPaellaaaadpevaeliaaqrq...lfearraalagelailqeqieqleeeieglraqlaalreqlalleeela 105 L+AE++++++ ++ l+++ + +++ q++ +e+ +l++e ++l+++++ +e ie +++ +++ + ++ l+e+l FUN_001065-T2 4433 LEAELSDLKEsFDIEMRTLKDR----YDVVVSEQQKhinNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTNFDHIISGLREDLH 4516 8888888855355543333333....34444444431115788888899999999999999999999888888888887777777776 PP == domain 35 score: -3.3 bits; conditional E-value: 4.6 HH_AprE 80 eeeieglraqlaalreqlalleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqq....iaeaelqiaqlraeyreeaae 169 e+eie l+ +a re+ lee++ +l + ++ G k +l+e + ++ le +i++l ae a + +q +++a + +++r+e++ + ++ FUN_001065-T2 4569 EAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDG---KGDLMEKQEQIQTLEEDIERLAAEHATSMEQlvleVNKAGKERDEIRKEMQINMDA 4659 55666666666666666666666666666666665...44555555555555555555555444433331111345555555555555555555 PP HH_AprE 170 eLrevqaelaeleerlra 187 + ++el++++e+++ FUN_001065-T2 4660 AVMQSNKELDQMKEQYTL 4677 555555555555555543 PP == domain 36 score: -0.1 bits; conditional E-value: 0.46 HH_AprE 31 tiefPaellaaaa.dpevaeliaaqrqlf....earraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreLlekG 114 +i+ a ++++++ ++++ q +l+ +++ ++l+gel+ ++ ie+l+ ei + ra l ++ + +l eel+++ +Lle G FUN_001065-T2 4654 QINMDAAVMQSNKeL----DQMKEQYTLLkensAKKMEQLEGELSEKRQVIEKLSDEIGQFRAGLVNKSDEEKLY-EELQANYQLLETG 4737 566666666666422....5555555555111156889*********************************9998.5788888888887 PP == domain 37 score: -4.6 bits; conditional E-value: 10 HH_AprE 63 aalagelailqeqieqleeeieglraqlaalreqla.lleeelaglreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelq 155 + +++ la l+ ++eq +++ + ++ + ++r +++ l+++ + + +L e G v + l + ++a+ + +i el+ ei+ +r++ ++ + + FUN_001065-T2 4761 KDYDQMLASLKLEVEQSRQQNLEKEKFIHNQRIEVEsLVRDKESLITKLRETGQVTRETLQRTDGDAAD-DDEIVELKNEISLLRKECQDCRVE 4853 6788999999999******999999999999977752678888889**********************9.789********************* PP HH_AprE 156 iaqlraeyreeaaeeLrevqaelael 181 +++l ++++ +++ +e+++ l e FUN_001065-T2 4854 KDKLYDKFHDAVESLRKELERSLHEK 4879 ******************99999875 PP == domain 38 score: -1.7 bits; conditional E-value: 1.4 HH_AprE 61 rraalagelailqeqieqleeeieglraqlaalreqlalleeelag 106 +++l +++++l++ q+e +g r l+a+r++ +ll+++l+ FUN_001065-T2 4896 LQQSLLEKQSALTKAKVQFEHIGKGWRNDLEAARAEKELLQKQLEE 4941 37899999999********************************985 PP >> ATG16 Autophagy protein 16 (ATG16) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.2 17.0 10 2.6e+04 61 162 .. 36 160 .. 5 208 .. 0.61 2 ? -9.0 25.5 10 2.6e+04 34 165 .. 227 352 .. 222 357 .. 0.69 3 ? 0.9 4.0 0.24 6.2e+02 98 160 .. 375 437 .. 362 447 .. 0.79 4 ? -12.7 32.7 10 2.6e+04 32 175 .. 456 600 .. 439 609 .. 0.53 5 ? -1.0 11.8 0.89 2.3e+03 84 149 .. 551 616 .. 545 627 .. 0.81 6 ? -6.4 15.3 10 2.6e+04 90 180 .. 683 766 .. 635 769 .. 0.65 7 ? -10.8 37.6 10 2.6e+04 34 162 .. 704 840 .. 687 848 .. 0.51 8 ! 7.6 10.0 0.0021 5.3 92 162 .. 837 907 .. 835 915 .. 0.94 9 ! 8.6 9.5 0.001 2.6 83 158 .. 912 987 .. 905 1004 .. 0.77 10 ! 11.0 10.9 0.0002 0.51 99 178 .. 1005 1084 .. 996 1089 .. 0.95 11 ! 16.4 20.5 4.2e-06 0.011 72 180 .. 1104 1212 .. 1084 1215 .. 0.88 12 ! 6.9 12.0 0.0036 9.3 72 178 .. 1230 1336 .. 1214 1341 .. 0.86 13 ! 6.5 18.6 0.0046 12 25 157 .. 1295 1431 .. 1295 1438 .. 0.84 14 ! 8.7 13.0 0.00099 2.5 88 168 .. 1439 1519 .. 1433 1521 .. 0.95 15 ! 19.6 15.8 4.7e-07 0.0012 91 184 .. 1530 1623 .. 1526 1625 .. 0.97 16 ! 13.8 15.9 2.6e-05 0.068 99 178 .. 1646 1725 .. 1634 1730 .. 0.96 17 ? -3.5 4.3 5.3 1.4e+04 88 147 .. 1733 1792 .. 1722 1825 .. 0.55 18 ? 3.1 19.6 0.05 1.3e+02 30 164 .. 1779 1908 .. 1756 1915 .. 0.67 19 ? 3.9 18.7 0.028 73 72 181 .. 1917 2026 .. 1908 2033 .. 0.93 20 ? 5.3 5.1 0.011 27 107 161 .. 1994 2048 .. 1985 2051 .. 0.82 21 ! 11.6 23.8 0.00013 0.32 66 168 .. 2047 2156 .. 2029 2160 .. 0.83 22 ! 7.0 12.0 0.0033 8.3 75 162 .. 2133 2220 .. 2131 2225 .. 0.90 23 ? -3.6 15.5 5.6 1.4e+04 99 179 .. 2261 2341 .. 2242 2349 .. 0.80 24 ? -12.8 33.8 10 2.6e+04 30 182 .. 2381 2534 .. 2350 2540 .. 0.66 25 ? -8.1 35.4 10 2.6e+04 29 177 .. 2442 2585 .. 2421 2591 .. 0.74 26 ? -2.0 21.4 1.8 4.6e+03 39 156 .. 2614 2718 .. 2600 2724 .. 0.49 27 ? -4.1 35.3 8.3 2.1e+04 32 166 .. 2702 2833 .. 2695 2844 .. 0.59 28 ? -1.7 16.2 1.5 3.8e+03 41 171 .. 2875 3011 .. 2867 3030 .. 0.67 29 ? -6.6 17.9 10 2.6e+04 32 147 .. 2912 3029 .. 2902 3069 .. 0.62 30 ? 0.5 2.6 0.32 8.1e+02 132 179 .. 3068 3115 .. 3037 3123 .. 0.83 31 ? -4.7 19.7 10 2.6e+04 27 185 .. 3264 3422 .. 3249 3424 .. 0.67 32 ? -4.8 16.3 10 2.6e+04 88 164 .. 3413 3487 .. 3408 3506 .. 0.76 33 ? -1.3 32.4 1.1 2.8e+03 63 181 .. 3527 3650 .. 3495 3656 .. 0.76 34 ? -2.4 10.5 2.4 6.2e+03 29 120 .. 3672 3765 .. 3651 3792 .. 0.70 35 ? -0.6 16.3 0.72 1.8e+03 53 151 .. 3775 3876 .. 3756 3884 .. 0.72 36 ? 1.4 27.2 0.17 4.4e+02 37 185 .. 3807 3956 .. 3801 3958 .. 0.80 37 ? 1.6 7.8 0.15 3.7e+02 100 153 .. 4128 4181 .. 4116 4189 .. 0.87 38 ? -8.7 35.6 10 2.6e+04 26 184 .. 4243 4387 .. 4219 4417 .. 0.77 39 ? -0.7 9.9 0.77 2e+03 94 176 .. 4395 4489 .. 4388 4493 .. 0.50 40 ! 8.1 10.8 0.0015 3.9 118 189 .. 4565 4636 .. 4522 4647 .. 0.88 41 ? -2.4 11.9 2.4 6.2e+03 106 167 .. 4656 4714 .. 4629 4735 .. 0.65 42 ? -2.8 18.9 3.4 8.7e+03 14 168 .. 4721 4873 .. 4709 4879 .. 0.67 43 ? -0.3 15.6 0.56 1.4e+03 81 170 .. 4863 4952 .. 4860 4961 .. 0.90 Alignments for each domain: == domain 1 score: -5.2 bits; conditional E-value: 10 ATG16 61 skkekeasass..................qsakiqsleqklaqlreel.aeaqrsrgelaqrllelneelqelek...klrederrlaeleaeraq 134 ++ ++e++ ++ ++ + + e++l+qlre + a s +e+a++++++n+ +q + l+++++ + +le+++++ FUN_001065-T2 36 PPPKDEDTIADlrralsesemrneginreFQKLLRQKEEELVQLRENVrAGPSLSPSEFASEVQDANNPVQNIQHvqvLLAQKDEVIGDLEKQLHE 131 222333333333444444445556776666677888888888888887356788888888888888876665544333788888888888888888 PP ATG16 135 leeklkdreeelreka.klvedlqDElva 162 e ++++e++ r+++ k++++l + a FUN_001065-T2 132 SEAHVRRLEQQGRDNEeKVMHELAVKIRA 160 88888888888877651344444444444 PP == domain 2 score: -9.0 bits; conditional E-value: 10 ATG16 34 leaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaele 129 ea n + e++ +a +++ ++ k ++ ++ +s+ i+s e++ + + l + q +e++q +l+l+ ++e+ek l+ + ++ +++ FUN_001065-T2 227 IEAMNTRVEKSVDEAGRAKREISALK----KELEE---KSELIASAEKLEQEKSSLLMQIQEIEKEHKQTVLRLQHDVEEKEKALAVEFAEAEQVY 315 34444444444444333222222222....22222...23455566655555566677888889999*********************99999986 PP ATG16 130 aer.aqleeklkdreeelrekaklvedlqDElvaLnl 165 +++ ++l+e+l+++++ ++ k+++++ l+ +++ nl FUN_001065-T2 316 KTNeHDLRERLDEKAQIIESKDEAIQVLKRAIQEKNL 352 6551679***********************9998777 PP == domain 3 score: 0.9 bits; conditional E-value: 0.24 ATG16 98 gelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDEl 160 +e ++++ +l+e+++ lek + ++++++ l++++ + +k ++e l++k++ ++ +++ + FUN_001065-T2 375 KEREEMIRSLSEKMNFLEKGSVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKH 437 566778888888888899999999999999999999988888888888888888887776655 PP == domain 4 score: -12.7 bits; conditional E-value: 10 ATG16 32 alleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlae 127 ++l++ a+l+ + ++ +++++ +++ +++++++ +++ q+ ++ +l +l+ ++ +++++++l+e+ +e++++ek+ + ++++ + FUN_001065-T2 456 EELQKMVASLKDSLSELESKEKVTERLL---LLDAEKEQQFRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEARAEIEAKEKEVKDLNSKIGK 548 2233333333333333333222222222...22222333334455555566666666666666666667777777777776666666666666654 PP ATG16 128 l....eaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklr 175 l +a+++ l+ + +++ +e++e++ + ++E a + + +++Ee+++ FUN_001065-T2 549 LklqaKAKVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKE 600 4111245566666666666666666666666666666666666666666665 PP == domain 5 score: -1.0 bits; conditional E-value: 0.89 ATG16 84 aqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrek 149 +q ++ ++ +q ++++l+++ +el+ l +++ + ++++++ e+e++ e+k+ ++e+ l+e FUN_001065-T2 551 LQAKAKVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQALEEF 616 566777888888888888888888888888888888888888888888888888888888888875 PP == domain 6 score: -6.4 bits; conditional E-value: 10 ATG16 90 laeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekE 180 l ++r +++++ el+e l++ +++ +++++++++ e++ + + + ve+lq+E ++L++ l+ ++l +l++E FUN_001065-T2 683 LDLITKERDSFKSKVEELEEMLEAEKEQQQKKAEEISS-------DEDAEHAKHMAEESLMMHVEALQEENETLRVSLDLEKSALANLKEE 766 55555666666666666666666665555555555543.......3333333333334455667788888888888888888888888877 PP == domain 7 score: -10.8 bits; conditional E-value: 10 ATG16 34 leaenakleseaasatpsssqstsskkskkekeasass...................qsakiqsleqklaqlreelaeaqrsr.gelaqrllelne 109 leae+++ +++a++ ++ ++++ ++ + ++ +++la l+eel++aq + +el ++ +l + FUN_001065-T2 704 LEAEKEQQQKKAEEISSDEDAEHAK------------HmaeeslmmhvealqeenetLRVSLDLEKSALANLKEELKQAQLNQeNELHSEMDSLRQ 787 3333333333333333222222111............11122233343334444334455555666677777777777776552466666666666 PP ATG16 110 elqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElva 162 l+e ++k+ ++l+ ++e+a+ +++++ +e+el++k+ +ve+l l++ FUN_001065-T2 788 VLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQ 840 66666666666666666666666666666666666666666666666555544 PP == domain 8 score: 7.6 bits; conditional E-value: 0.0021 ATG16 92 eaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElva 162 ++q+s +e ++ l ++ +e++ l+ l+e+++ + l+a+ ++ + +l++++e+l++k++ ve lq E++ FUN_001065-T2 837 QLQQSTQERNKVLEDKDKEISNLQGALMENSSGFEVLNASFSESTIQLDRLQEQLAAKEAEVERLQKEMSE 907 58899999999*********************************************************985 PP == domain 9 score: 8.6 bits; conditional E-value: 0.001 ATG16 83 laqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqD 158 ql+ + + + +e++ l +++e+l++ ++ + +++++l++l+++ +l+ ++++++ + +k++ ++ l+ FUN_001065-T2 912 HEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDDKEAEIAHLKA 987 5666777777777788888899999999999999999999999999999999999999999888888888887775 PP == domain 10 score: 11.0 bits; conditional E-value: 0.0002 ATG16 99 elaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrkle 178 e ++l++l+e +q++e++l++ +++ +e ++ ++l++ +++++ +l+++++++ + DE++ L+ +l+ +E+ l++l FUN_001065-T2 1005 ESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLA 1084 6789**********************************************************************999885 PP == domain 11 score: 16.4 bits; conditional E-value: 4.2e-06 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDE.lvaLn 164 ++ +++++e++l + e + + +s +e + ++e+n++l+++e+k ++ +++l+e a++++l+ ++ r+++l +++kl+ +++DE +++L+ FUN_001065-T2 1104 KDVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLL-IAKDEcVQTLE 1196 467889999***********************************************************************99.566663689** PP ATG16 165 lqlnmaEeklrklekE 180 +l+ +E+ ++le+E FUN_001065-T2 1197 NTLKEIEKSHQQLESE 1212 **************99 PP == domain 12 score: 6.9 bits; conditional E-value: 0.0036 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnl 165 ++++i +l++k+ +l+ + +e+ s +e +++ el + l+ +e++l+ + ++++ ++ +ql+ +l+ + +l+e++ ++ + D +++L+ FUN_001065-T2 1230 KDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLER 1323 4678999999999999999999999999999999999999999999999999999999999999999999999999999999999999999998 PP ATG16 166 qlnmaEeklrkle 178 ++ +++++le FUN_001065-T2 1324 DVEATLQQYKDLE 1336 8887777777776 PP == domain 13 score: 6.5 bits; conditional E-value: 0.0046 ATG16 25 nrLldrtalleaenakleseaasatpsssqstsskkskkekeasass.....qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqe 113 +rL+ ++++l++ + +l+++ + ++ +++ ++ ++ k +s+++ +++i++ e++ a+l +e++e+ + +el++r e+n++l++ FUN_001065-T2 1295 SRLAGQSSQLQELTITLSNKEDQISSLERDVEATLQQYKD-LESRHNsdvlkLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKA 1387 6899999999999999977766666655555554433333.3333335899999**************************************** PP ATG16 114 lekklrederrlaeleaeraqleeklkdreeelrekaklvedlq 157 l++ +e+e++l el+a++++ + lk+ ++ l+ ++ v lq FUN_001065-T2 1388 LQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQ 1431 *********************************99988877776 PP == domain 14 score: 8.7 bits; conditional E-value: 0.00099 ATG16 88 eelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqln 168 ++l+e++ +e++++l+el e l+ +e++++ +++++e +a ++qle +l++ ++ e+ +++ + E+++Ln+ l+ FUN_001065-T2 1439 ADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSLS 1519 58899999999******************************************************************9986 PP == domain 15 score: 19.6 bits; conditional E-value: 4.7e-07 ATG16 91 aeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeL 184 +e+q + g l+++l e++ee+q+le++l e+++++++l +++++ +++l+d++ +l+ k+ ++++ +aL+ ++ a +++++++kE +eL FUN_001065-T2 1530 SELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYENAVSENENIQKELDEL 1623 7899999***********************************************************************************8887 PP == domain 16 score: 13.8 bits; conditional E-value: 2.6e-05 ATG16 99 elaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrkle 178 e++++l+++nee+q lekkl +++l+ ++e+++l k+ ++++el ++++ + l DE + L+ qln+ E++++++e FUN_001065-T2 1646 EHKNQLQAKNEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNME 1725 7899************************************************************************9987 PP == domain 17 score: -3.5 bits; conditional E-value: 5.3 ATG16 88 eelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelr 147 e ++++ +r+e ++ l l++el+ + ++++ ++ +++l+ +++ +++ ++++e l+ FUN_001065-T2 1733 EKMSQVEFERNEVQSGLDHLKKELDLKLREATDLREVIDHLKGVNEEISRAAAENAECLK 1792 333344444555555555555555555555555555555555555555555555555554 PP == domain 18 score: 3.1 bits; conditional E-value: 0.05 ATG16 30 rtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklreder 123 ++ +aena+ ++ a++++ + s++ s++ ++ +ak+ ++e+ ++l+++ ++ + ++rl e+ e + l+k l+e ++ FUN_001065-T2 1779 EISRAAAENAECLKTEILAKENELHKVSQSLSSNMIMLEE--IQAKLIESEKCSTKLKDDF---ELEKDDWKTRLEEAACENSSLKKGLSEMTE 1867 4444444444444333333332222222222222222222..3366666777777777765...357888999999999999999999999999 PP ATG16 124 rlaeleaeraqleeklkdreeelrekaklvedlqDElvaLn 164 + ++l+++++ ++ lk+ +eel+ k++++ +lq E++ L+ FUN_001065-T2 1868 KQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHLQ 1908 99999999999999999999999999999999999999887 PP == domain 19 score: 3.9 bits; conditional E-value: 0.028 ATG16 72 qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnl 165 qs+k ++l++++++ + e e+q++ ++ + l++++ e++el++ + e++++l+ +++++++l+e+ + +ee + +lq l+ + FUN_001065-T2 1917 QSQKGETLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMAS 2010 6788899*************************************************************************************** PP ATG16 166 qlnmaEeklrklekEN 181 +l+ + +++ +le++ FUN_001065-T2 2011 ELRRVSQEKTELESDV 2026 ************9985 PP == domain 20 score: 5.3 bits; conditional E-value: 0.011 ATG16 107 lneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElv 161 + ee + l+++l+e +++l+++++e+++le + d++++lr ++ +++++++l+ FUN_001065-T2 1994 AVEETSNLQANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLT 2048 5577888999999999999999999999999999999999999998888888765 PP == domain 21 score: 11.6 bits; conditional E-value: 0.00013 ATG16 66 easass....qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdree...elrekakl 152 ++as+ ++++i+sle+ +++l++ l+e+qr+ ++l + l ++n+el+ ++ +e+e++l+el++er++ +e+l+ ee +l+e + FUN_001065-T2 2047 LTNASEgittRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERLSAAEEvfsKLQEMESF 2140 3333335556899*****************************************************************9999833356677777 PP ATG16 153 vedlqDElvaLnlqln 168 +l+ E ++L+ +l+ FUN_001065-T2 2141 YGALKQEKESLKTELE 2156 7799999999998886 PP == domain 22 score: 7.0 bits; conditional E-value: 0.0033 ATG16 75 kiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElva 162 k+q++e+ +l++e + + + ++ ++ l+e ++e + l+++l + +rl++l++er+q++ +l+++++el++ ++ v lq +++ FUN_001065-T2 2133 KLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISS 2220 56788888889999999999999999************************************************99999999876655 PP == domain 23 score: -3.6 bits; conditional E-value: 5.6 ATG16 99 elaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklek 179 + ++ +l+ e + l ++l+e +l+e+++++ + ++l d +e+l+ +a + e + El+ + +++ +E++l +l++ FUN_001065-T2 2261 QQVSQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQ 2341 444555666667777778899999999999999999999999999999999999999999999999999999999998885 PP == domain 24 score: -12.8 bits; conditional E-value: 10 ATG16 30 rtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrlle.lneelqelekklrede 122 r+++l ++ + + +++ +++ q+t+ ++++ ++ +++ ++ki+ ++++a+ + la+a ++++e q+l + l ++ +++++ l+e + FUN_001065-T2 2381 RIEELTIAKELEKAQVEEKLTKQLQDTK-THKDGVIAKLKDKVREKIELNKKNIAEFKVKLANANKEKEETLQELHSqLANAEKDKKAALEELK 2473 4444433333333333333322222222.22333333333337889999999999999999999999999988886415555566666777777 PP ATG16 123 rrlaeleaeraqleeklk.dreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENk 182 l++ ++e+ q + l+ ++++ ++ek+++v++lq l+ + +++ ++l++l++ N+ FUN_001065-T2 2474 LFLDNSQKEKDQALQDLElQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRDNNR 2534 7788888888776666654788999999999999999999988889999999999998887 PP == domain 25 score: -8.1 bits; conditional E-value: 10 ATG16 29 drtalleaenakleseaasatpsssqstsskkskkekeasass...........qsakiqsleqklaqlreelaeaqrsrgelaqrllelneel 111 + ++ e+ ++l+s+ a+a++ +++ + q++k q+l+++ +ql + ae +el+++l +++ FUN_001065-T2 2442 NANKEKEETLQELHSQLANAEKDKKA----------------AleelklfldnsQKEKDQALQDLELQLAKAIAEKEEVVQELQSQLEIQSQTT 2519 22222222222222222222222222................122344555555667778888888888888888888899************* PP ATG16 112 qelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrkl 177 ++l + l + + + + +e++ l++kl d e+e ++k+ +++ +l+ L+l+ ++ E+++ ++ FUN_001065-T2 2520 EQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEM 2585 *************************************************************98665 PP == domain 26 score: -2.0 bits; conditional E-value: 1.8 ATG16 39 akleseaasatpsssqstsskkskkekeasass.......qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrl 125 ++l++e a+ kk + ++k ++ eq+ a ++eel e+++ ++l++ ++l+++ ++le+ + e ++ FUN_001065-T2 2614 KRLKEERAA-----------KKD---------ElaklqgsIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEM 2687 333222111...........111.........01111122234556666777777777777777666666555555555555555555555555 PP ATG16 126 aeleaeraqleeklkdreeelrekaklvedl 156 +l++++ + +++ kd+e++ ++++k +e++ FUN_001065-T2 2688 INLKRDLDEITKEKKDLERNHEQLKKELEEQ 2718 5555555555555555555555555555544 PP == domain 27 score: -4.1 bits; conditional E-value: 8.3 ATG16 32 alleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrs...rgelaqrllelneelqelekklrede 122 + le+ ++l++e +++++ ++s + +s++e+ ++ k+++l+ +l +l+ee++e r+ ++e +q l++ ++l+e ++l++++ FUN_001065-T2 2702 KDLERNHEQLKKELEEQETDFTSSVDALSSQREN------ADRKTEELQLQLDALNEEVSEKKREevnQQEEKQLLVDQVQQLSEAVQTLKNKD 2789 4455566666555555444333332222111111......223456777777777777777766422255566667777777777777777777 PP ATG16 123 rrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlq 166 + + +le+e++ +e+ +++e+l +++ + l+D++++L+++ FUN_001065-T2 2790 QDIVRLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYDQLQAA 2833 77777777777777777777777777777777777777777765 PP == domain 28 score: -1.7 bits; conditional E-value: 1.5 ATG16 41 leseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelek.....klrederrlaele 129 l++e+ +++s +t +++ + +++a +++++++ +l ++++el++a +++l+ ++ ++ +++ + +++ ++++++++ FUN_001065-T2 2875 LQEEIPVVQQSVPLQTEPSSVQPSEPAAG---HDDLHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSEsvrdvESSDMKAEIDKAR 2965 55555555555555555555555555554...45999999999999999999999999999999988777777666344446667778888888 PP ATG16 130 aeraqleeklkdreeel....rekaklvedlqDElvaLnlqlnmaE 171 +e+ +le+ +++eel rek+ ++ dl+ + +L + + +E FUN_001065-T2 2966 QEKINLEKTALELREELveivREKDGTIGDLKQKIRQLLNEKSRNE 3011 8888888776665555422227777777777777766666555555 PP == domain 29 score: -6.6 bits; conditional E-value: 10 ATG16 32 alleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrlle....lneelqelekklred 121 +l++ +a+l ++ a +++ + + + kke ++s+s ++ +++++++++ + r+e ++ ++ el ++l+e + ++ +l++k+r+ FUN_001065-T2 2912 MELKEIQAELTKAKALNEK--LKAKVRVFMKKERAKSESVRDVESSDMKAEIDKARQEKINLEKTALELREELVEivreKDGTIGDLKQKIRQL 3003 4566666666555433333..3333333333444444444678888888888888888888888877777776651111344455555555555 PP ATG16 122 errlaeleaeraqleeklkdreeelr 147 ++ ++ e +++ e+ l++r+ee++ FUN_001065-T2 3004 LNEKSRNEVLVEKYEKLLAERDEEIK 3029 55555555555555555555555554 PP == domain 30 score: 0.5 bits; conditional E-value: 0.32 ATG16 132 raqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklek 179 +++le + +e+ l++k++ + +++ Elv+ n++ + + +lr++++ FUN_001065-T2 3068 VQELENTKDGYEKVLSDKDEEIGNFKRELVSCNIETEELKGRLRQTQE 3115 667788888888999999999999999999999999999999998887 PP == domain 31 score: -4.7 bits; conditional E-value: 10 ATG16 27 Lldrtalleaenakleseaasatpsssqstsskkskkekeasass......qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqel 114 L + ++l ++ +++l+++ ++ +++ss + + ++e + +a ++++++a+lr el + ++++ + +++++ l FUN_001065-T2 3264 LKQASDLNNKLKEALKKKRSKPRSKSSGEHEM---SNE------TiaelevIRAAKVESDKQMAHLRLELDNFVQEKERI---VAGFKSKMEML 3345 33334444444444433332222222111111...222......1234556455556677889**********8777655...66677777777 PP ATG16 115 ekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElv...aLnlqlnmaEeklrklekE...NkeLv 185 ++ ++ ++ ++e e+++ + ++++d++ + ++ +++l+ +++ L+l+l+ +++ +le++ Nk+Lv FUN_001065-T2 3346 ADEKERANSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVEnlpELKLELQLTVQENAELENDlryNKSLV 3422 77888888899999999999999999999999999999999998876222579999999999999999866677777 PP == domain 32 score: -4.8 bits; conditional E-value: 10 ATG16 88 eelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLn 164 ++l +e +r++el+ el+ +e+k ++ ++++e ++++ l k k+ +e + e+++ + +lqD l++ FUN_001065-T2 3413 NDLRYNKSLVKESTDRVSELKRELESREEKHLKEIEEIKERHDQV--LIAKQKETDEAILELRQINTELQDNLQSVS 3487 555555555567888899999988888888888888888766665..66677799******************9976 PP == domain 33 score: -1.3 bits; conditional E-value: 1.1 ATG16 63 kekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekk.lrederrlaeleaeraqleeklkdreeelrek....ak 151 ++ e+++ ++++ i +le ++l+e+++e+ sr+el+++l e+ +e+++++ + r+ e++ +el++e++ l+++++++e++ +e+ ++ FUN_001065-T2 3527 SQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRfQRSVEEKETELREEKEGLQQQMQQLEAKFEELlsqsQA 3620 223333333578899************************************997526778889999***********99998776665222277 PP ATG16 152 lvedlqDElvaLnlqlnmaEeklrklekEN 181 + +l +El+ n++l + ekl++ E FUN_001065-T2 3621 SISKLEEELAHTNMELVSFNEKLQTADGEK 3650 7779************99999999877665 PP == domain 34 score: -2.4 bits; conditional E-value: 2.4 ATG16 29 drtalleaenakleseaasatpsssqstsskkskkekeasass..qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklre 120 +++ +a +++l e + + ++ ++s++ ++++ + + +++ s+ +++++ + a lr+ l++++ +r l++rl + + l+++ +k + FUN_001065-T2 3672 QQAINARAAAEELAHEFQVQLEKMRKSNPTTANEVDEISPPQEnkVSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVLSTKSEKEAL 3765 555566666666666666655555444444433333333333355889999999****************************999999887543 PP == domain 35 score: -0.6 bits; conditional E-value: 0.72 ATG16 53 sqstsskkskkekeasass...qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdre 143 ++++ +k ++ +s+++ +s ++++e ++ l++el+ + +++l+ +l ++ ++ + + ++ ed++ +el++e+++ +++ +re FUN_001065-T2 3775 NEDNVQKVVEEVILQSSEDnqvSSLPTSETEVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDSGDEDSSVRNELQTELEKIRQEKLERE 3868 23333333333333333334446777888999999****************************************************9999999 PP ATG16 144 eelrekak 151 + +e++ FUN_001065-T2 3869 KTCQELRL 3876 99998875 PP == domain 36 score: 1.4 bits; conditional E-value: 0.17 ATG16 37 enakleseaasatpsssqstsskkskkekeasass....qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrla 126 e ++l++e +++++ +++ +++ ++ +k++ +s+ +s+ ++l+++l ++r+e e ++++el + l + ++e+e+ ++e +rr++ FUN_001065-T2 3807 EIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDsgdeDSSVRNELQTELEKIRQEKLEREKTCQELRLE---LDTFVREKESITNELKRRID 3897 55555566666665555555544444444444333455466667899999999999999999999999965...5567999************* PP ATG16 127 eleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeLv 185 el+a++++ ++ ++d+e+++++k+ ++ +l ++ + ++a ++ ++l+ EN++L+ FUN_001065-T2 3898 ELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLL 3956 **********************************************************8 PP == domain 37 score: 1.6 bits; conditional E-value: 0.15 ATG16 100 laqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklv 153 ++r el+e+l++ ++++++ +++l+ ++++++le +++++e+el+e++++ FUN_001065-T2 4128 IETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMK 4181 56666799*****************************************99875 PP == domain 38 score: -8.7 bits; conditional E-value: 10 ATG16 26 rLldrtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklr 119 ++++ ++ +a n++l+++ ++ +++ ++ ++ s++++ ++l+++la++r+e e+ r+ ++l ++l e ++e+e++ FUN_001065-T2 4243 KMQNELDKVKAVNERLKTKLKTLMRKRKGGKVET-----------SEEENREELHTELAKVRQEKLETERAAQQLR---IDLDEIVREKERRVV 4322 5556666666777777666555554333332222...........1234556799999999999999988877776...567778999999999 PP ATG16 120 ederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeL 184 e + r++++ +e+++++ l+ +e+ l e+++++ l + +++L +l +E+ l + +EN++L FUN_001065-T2 4323 EHKTRMQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNL 4387 99999999999999999999999999999999999999999999999999999999999999988 PP == domain 39 score: -0.7 bits; conditional E-value: 0.77 ATG16 94 qrsrgelaqrllelneelqelek....klrederrlaeleaeraqleek.......lkdr.eeelrekaklvedlqDElvaLnlqlnmaEeklr 175 q ++ + + +l +++ el++l + l+e+e+r+++leae+++l+e lkdr + ++e++k +++l l +Ln + +++E++ + FUN_001065-T2 4395 QLQKVKAERELHAATGELERLLEgdrpILAEKEQRISNLEAELSDLKESfdiemrtLKDRyDVVVSEQQKHINNLESTLGSLNTEKKQLESRVK 4488 4444444444444444444443322224555666666666666666554111111155552334567777777777777777777777777666 PP ATG16 176 k 176 FUN_001065-T2 4489 A 4489 5 PP == domain 40 score: 8.1 bits; conditional E-value: 0.0015 ATG16 118 lrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnmaEeklrklekENkeLveRWm 189 l+ +e+++++l++ +aq +e+ d+ee++ +++k+v+d + +l + q + +Ee ++l +E + e+++ FUN_001065-T2 4565 LSDNEAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEHATSMEQLV 4636 6778999*****************************************************999776666555 PP == domain 41 score: -2.4 bits; conditional E-value: 2.4 ATG16 106 elneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlql 167 ++ +++ + +k+l + +++ + l++ + +k++++e el+ek++++e+l DE+ + ++ l FUN_001065-T2 4656 NMDAAVMQSNKELDQMKEQYTLLKE---NSAKKMEQLEGELSEKRQVIEKLSDEIGQFRAGL 4714 5555555555566655555555554...445789999*****************98887665 PP == domain 42 score: -2.8 bits; conditional E-value: 3.4 ATG16 14 ekafaelieaYnrLldrtalleaenakleseaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllel 107 ek+++el ++Y+ L ++l++ +e+++ + + ++ + ++ k + ++s +++ + e+ ++ +r e++ + r ++ l ++l e+ FUN_001065-T2 4721 EKLYEELQANYQLLETGNNKLRQDLYLTMKETENLRM-KLKKDYDQMLASLKLEVEQS-RQQNLEKEKFIHNQRIEVESLVRDKESLITKLRET 4812 5566666555555444444444444444333333333.22222223333333333333.6778899999**********************997 PP ATG16 108 neelqe...lekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqln 168 + +e + + ++d+ ++ el++e++ l+++++d + ek+kl ++++D++++L+ +l+ FUN_001065-T2 4813 GQVTREtlqRTDGDAADDDEIVELKNEISLLRKECQDCR---VEKDKLYDKFHDAVESLRKELE 4873 55444400044456788999***************9977...579**************98875 PP == domain 43 score: -0.3 bits; conditional E-value: 0.56 ATG16 81 qklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleeklkdreeelrekaklvedlqDElvaLnlqlnma 170 +++ +lr+el+ ++ ++ +laq+ e+ ++ +el+++l e++++l++++ + ++ + ++ e r+ ++l++++ +E ++ ++ + a FUN_001065-T2 4863 DAVESLRKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHIGKGWRNDLEAARAEKELLQKQLEERTSQSVTIDIA 4952 67899*********************************************************************9999988877666665 PP >> FKBP15 FK506-binding protein 15-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -7.3 15.7 10 2.6e+04 105 220 .. 95 209 .. 54 212 .. 0.66 2 ? -9.9 33.6 10 2.6e+04 51 210 .. 168 340 .. 163 353 .. 0.66 3 ? -9.6 30.0 10 2.6e+04 72 209 .. 362 507 .. 331 517 .. 0.54 4 ! 7.3 23.5 0.0018 4.6 91 193 .. 519 618 .. 509 646 .. 0.88 5 ? -4.8 49.3 8.6 2.2e+04 41 221 .. 669 860 .. 666 866 .. 0.79 6 ? 3.1 17.6 0.033 84 88 196 .. 882 990 .. 872 999 .. 0.74 7 ! 9.3 15.8 0.00042 1.1 89 198 .. 981 1090 .. 977 1096 .. 0.89 8 ! 5.5 24.9 0.0063 16 59 190 .. 1074 1215 .. 1072 1220 .. 0.82 9 ? 3.6 11.0 0.023 59 86 175 .. 1181 1270 .. 1175 1291 .. 0.83 10 ? 2.7 30.2 0.046 1.2e+02 21 221 .. 1222 1431 .. 1219 1433 .. 0.81 11 ? 2.0 25.6 0.074 1.9e+02 58 196 .. 1374 1512 .. 1370 1522 .. 0.83 12 ! 18.9 25.8 4.9e-07 0.0013 83 218 .. 1515 1656 .. 1510 1665 .. 0.83 13 ? -3.6 26.6 3.9 1e+04 87 194 .. 1655 1761 .. 1632 1793 .. 0.49 14 ? -3.0 34.8 2.4 6.2e+03 12 190 .. 1780 1951 .. 1776 1952 .. 0.68 15 ! 7.9 19.4 0.0011 2.9 85 212 .. 1923 2050 .. 1915 2053 .. 0.92 16 ? 3.8 26.5 0.02 52 85 190 .. 2049 2157 .. 2035 2160 .. 0.72 17 ! 8.8 13.7 0.00059 1.5 79 159 .. 2144 2224 .. 2142 2234 .. 0.69 18 ? -1.7 34.5 0.96 2.5e+03 59 211 .. 2249 2405 .. 2244 2421 .. 0.85 19 ? -9.7 45.4 10 2.6e+04 27 192 .. 2409 2586 .. 2402 2605 .. 0.81 20 ? 0.8 33.0 0.17 4.4e+02 87 211 .. 2599 2724 .. 2578 2733 .. 0.67 21 ? -5.3 27.1 10 2.6e+04 107 211 .. 2715 2818 .. 2714 2835 .. 0.63 22 ? -1.3 20.7 0.76 1.9e+03 103 214 .. 2906 3022 .. 2896 3030 .. 0.73 23 ? 3.0 16.3 0.037 95 26 192 .. 2986 3156 .. 2980 3169 .. 0.82 24 ? 0.2 13.8 0.27 6.8e+02 101 214 .. 3261 3364 .. 3239 3374 .. 0.73 25 ? -4.9 53.2 9.7 2.5e+04 12 223 .. 3401 3610 .. 3395 3614 .. 0.81 26 ? 3.3 34.1 0.03 77 66 216 .. 3516 3674 .. 3505 3678 .. 0.72 27 ? -2.7 12.1 2 5.2e+03 70 156 .. 3616 3702 .. 3610 3753 .. 0.58 28 ? -7.2 7.0 10 2.6e+04 100 139 .. 3717 3756 .. 3689 3795 .. 0.65 29 ? -14.3 34.9 10 2.6e+04 91 216 .. 3802 3920 .. 3712 3924 .. 0.75 30 ! 6.2 16.0 0.0039 9.9 104 215 .. 3882 3993 .. 3876 4005 .. 0.83 31 ? -3.6 13.1 3.7 9.4e+03 91 168 .. 3992 4070 .. 3987 4109 .. 0.57 32 ! 5.6 11.2 0.0059 15 98 186 .. 4098 4186 .. 4069 4193 .. 0.59 33 ? -8.2 24.6 10 2.6e+04 102 208 .. 4232 4344 .. 4211 4352 .. 0.69 34 ! 9.2 28.0 0.00045 1.2 12 187 .. 4328 4507 .. 4310 4548 .. 0.67 35 ! 4.9 17.1 0.0096 24 117 224 .] 4564 4675 .. 4530 4675 .. 0.80 36 ? -13.3 36.4 10 2.6e+04 20 220 .. 4687 4893 .. 4677 4895 .. 0.72 37 ? -12.0 33.0 10 2.6e+04 19 195 .. 4774 4946 .. 4772 4975 .. 0.75 Alignments for each domain: == domain 1 score: -7.3 bits; conditional E-value: 10 FKBP15 105 aalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlke.eKqkrkeleekltsleeeladlkaekeslekslsdrkkkaa..e 197 a+ +++++ +++++++ +++++e + +l++q +e+e++v +l+qq ++ e + el k+++ e + + e++++ l+dr k ++ FUN_001065-T2 95 ASEVQDANNPVQNIQHVQVLLAQKDEVIGDLEKQLHESEAHVRRLEQQGRDnEEKVMHELAVKIRAAEG----FQLKLEETKQLLEDRNKTVEglM 186 444555666667788888888888999999999999999999999999886234445666666666553....44555555666666666555223 PP FKBP15 198 erkrleeeleelkksleeeiqsL 220 +r +++ l e++ ++ ++++ + FUN_001065-T2 187 DRLDAQKRLIETRDQVIDQLKAM 209 55556666666666666666555 PP == domain 2 score: -9.9 bits; conditional E-value: 10 FKBP15 51 vEqsnlllEqrndslkstae..qsqarvleleqek...........vklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeele 133 +E+ ++llE rn +++ + +q+r++e + +e + ++q+ +++++++ ++ + ++s++++e+e+++e ++ FUN_001065-T2 168 LEETKQLLEDRNKTVEGLMDrlDAQKRLIETRDQVidqlkamknldSGADELVGTLREQIEAMNTRVEKSVDEAGRAKREISALKKELEEKSELIA 263 6888888888888888766522578888877654333322332322222222345667777777777777788888999***************** PP FKBP15 134 klraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerkrleeeleelk 210 + ++ ++e+ + + ++++ ke Kq+ +l++ +++ e la ae+e++ k+ + + +e++++ e +e+ FUN_001065-T2 264 SAEKLEQEKSSLLMQIQEIEKEHKQTVLRLQHDVEEKEKALAVEFAEAEQVYKTNEHDLRERLDEKAQIIESKDEAI 340 *************************9888877777777766666666666666554444444444444444444433 PP == domain 3 score: -9.6 bits; conditional E-value: 10 FKBP15 72 sqarvleleqekvklteeLaaataq....l....selqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqk 159 +++v++l +ekvk ee+ + ++ l + ++e++ l+k + s+++ ++++++ +++e++ +++++e ++++e + +l ++ ++ FUN_001065-T2 362 HSDKVMALLEEKVKEREEMIRSLSEkmnfLekgsVDKTSEIDFLKKSIDDKASTIKVLQETLQAKDQEIAGIKEKHE---TEMSEKEMKLSSQIKS 454 34678888888877666653332220000211112234555666666666666666666666666666665555443...3333334444444456 PP FKBP15 160 rkeleekltsleeeladlkaekesleksl...sdrkkkaaeerkrleeeleel 209 + el++ ++sl++ l++l+++++ +e+ l +++ +++ +e++ + + + l FUN_001065-T2 455 NEELQKMVASLKDSLSELESKEKVTERLLlldAEKEQQFRDEKQAFHDSEKAL 507 67777888888888888888888888864222345556666666666655555 PP == domain 4 score: 7.3 bits; conditional E-value: 0.0018 FKBP15 91 aaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslek 186 ++ + +l e+ e++a +k+ ++l+sk+ +++ +++ +++ l++++e l ++++el+ +l +e++++ ++++k++++eee + ++++ +le+ FUN_001065-T2 519 SKMSDELIEARAEIEAKEKEVKDLNSKIGKLKLQAKA---KVTGLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAETKRTELEQ 611 5678899999*******************99987765...9999**************************************************** PP FKBP15 187 slsdrkk 193 +l++ + FUN_001065-T2 612 ALEEFVR 618 *998544 PP == domain 5 score: -4.8 bits; conditional E-value: 8.6 FKBP15 41 seLleknqryvEqsnlllEqrndslkstaeqsqarvleleqek.......vklteeLaaataql.selqlelaalqkkeaelqsklssalqesekq 128 + le++ ++E++ l+ + ds+ks e+ + +le+e+e+ ++ +e+ ++a+ +l + ++alq++++ l+ l+ ++ +++ FUN_001065-T2 669 MKILEEERYCMERRLDLITKERDSFKSKVEE-LEEMLEAEKEQqqkkaeeISSDEDAEHAKHMAeESLMMHVEALQEENETLRVSLDLEKSALANL 763 5788999999******************999.7889999999865566554444455444444413577889999999999*****9999999999 PP FKBP15 129 keeleklr.aqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerkrleeeleelkksle...eeiqsL 220 keel++ + +q++el++++++l+q l eeK+k+ +l ++l+ + e+a ++ e+le++l+ ++ +++ ++l++ ++e +k le +ei++L FUN_001065-T2 764 KEELKQAQlNQENELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQERNKVLEdkdKEISNL 859 999999874677899999*******************************99********9998888877766666666655555444111666666 PP FKBP15 221 r 221 + FUN_001065-T2 860 Q 860 5 PP == domain 6 score: 3.1 bits; conditional E-value: 0.033 FKBP15 88 eeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekes 183 +L+ ++ql + e+++lqk+ +e ++ ++++ ++ ++++++++ +++ee+++ +++++ ++ ++ +l ++ ++l +e+++l++ + FUN_001065-T2 882 IQLDRLQEQLAAKEAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDD 977 466777777777777777777777777777777778888888888888888888888888888888888888888888888888888888888777 PP FKBP15 184 lekslsdrkkkaa 196 e++++ k ++ FUN_001065-T2 978 KEAEIAHLKATTD 990 7777776665554 PP == domain 7 score: 9.3 bits; conditional E-value: 0.00042 FKBP15 89 eLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaeke 182 e+a+ +a e ++ ++l++ e +s+l+ +++ + +++el+++r++ e+ +++++l+q + e+ + + l+e l + e+e++dl ++ e FUN_001065-T2 981 EIAHLKATTDEKDMSFEHLNTSLIESTSQLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLE 1074 566666666777778889999999********************************************************************** PP FKBP15 183 slekslsdrkkkaaee 198 + e+sl+d + +e FUN_001065-T2 1075 NQEASLKDLATRCEES 1090 ********87777665 PP == domain 8 score: 5.5 bits; conditional E-value: 0.0063 FKBP15 59 Eqrndslk...staeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveel 149 E++ slk + e+s+++v ele + ++ + eL+a ++ l e le ++l+k ae + +++++++++k++e+ + l+a+ +e+++++e+l FUN_001065-T2 1074 ENQEASLKdlaTRCEESMTKVRELEGNCASKDVELKAMESALEERGLENERLNKSSAESERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKL 1167 6666666611145689****************************************************************************** PP FKBP15 150 kqql..keeKqkrke..l...eekltsleeeladlkaekeslekslsd 190 ++++ ++ K + l +e +++le+ l+++++++++le +l++ FUN_001065-T2 1168 TSDCshRDAKLDDLQklLiakDECVQTLENTLKEIEKSHQQLESELNE 1215 998722555544322112222566889999999999999999988887 PP == domain 9 score: 3.6 bits; conditional E-value: 0.023 FKBP15 86 lteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeela 175 l++ L a + + +l++ l++++k ++l+s+l++a+ + + k+++++ +++ l ekv l+ ++ e K + e+++++++l + l+ FUN_001065-T2 1181 LQKLLIAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMKNDIANKDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLT 1270 566678888899999999999999999999999999999999999999999999999999999999999999999999999998877554 PP == domain 10 score: 2.7 bits; conditional E-value: 0.046 FKBP15 21 rLkkevleksskieeqnekiseLl....eknqryvEqsnlllEqrnd.slkstaeqsqar..vleleqekvklteeLaaataqlselqlelaal 107 +k ++ +k++ i +++ek+++L e + ++ E s+++ E +lk+t + r v + +lt++La ++ql el+ l++ FUN_001065-T2 1222 GMKNDIANKDEEIVTLTEKVGALNldyeEMKTSFSEASSQMRELHDLlTLKETEL-TVLRtsVENQGSSHQQLTSRLAGQSSQLQELTITLSNK 1314 69*********************73333445569999999999876424444433.333312444444559*****************999999 PP FKBP15 108 qkkeaelqsklssalqese....kqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaae 197 + + + l+ +++++lq+++ ++++++ kl+++ +e+e++ ++l +++ke + el+++ ++ + l+ l++ ++ e++l + k e FUN_001065-T2 1315 EDQISSLERDVEATLQQYKdlesRHNSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASL-E 1407 9998888888887777765222267788999********************************************************99865.6 PP FKBP15 198 erkrleeeleelkksleeeiqsLr 221 e+ + ++++++ ++ e+e+ L+ FUN_001065-T2 1408 EKTACLKQMDDSLQRTETEVLRLQ 1431 89999999**99999999998776 PP == domain 11 score: 2.0 bits; conditional E-value: 0.074 FKBP15 58 lEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkq 151 l+ rn+ +++ + q+ e e+e +l+++L++ ta l++++ l++++++ lqs l++ l+++e+++ ++ ++q +el+e++ + ++ FUN_001065-T2 1374 LNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSILDEKLADLEESRMGFAENSNQLNELRERLRNKEE 1467 5567777777777777777788888899999999999999999999999999999999999999999999999999999999999999999999 PP FKBP15 152 qlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaa 196 + K++ e ++ +++le la++ ++ +l ++ls + k ++ FUN_001065-T2 1468 ESNLLKANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVD 1512 999999999999999999999999999999999999988877665 PP == domain 12 score: 18.9 bits; conditional E-value: 4.9e-07 FKBP15 83 kvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeelad 176 +++l+ee +++selq ++ alq++ ae ++++++++++++++++ +++l+++ +++ +++e+l++ql ++ k ++++k+++l+ ++ FUN_001065-T2 1515 NMSLSEECFYFDSRVSELQDKVGALQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKSYEN 1608 677888888889********************************************************************************** PP FKBP15 177 lkaekeslekslsd.rkkk..aaeerkrlee...eleelkksleeeiq 218 +e+e+++k+l + rk + + ee+ +e+ +l e k++l+++ + FUN_001065-T2 1609 AVSENENIQKELDElRKERevFLEEKDAMEKcltQLIEHKNQLQAKNE 1656 **************5444422346775555411166677777664443 PP == domain 13 score: -3.6 bits; conditional E-value: 3.9 FKBP15 87 teeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkae 180 +ee + +++l +++ l+ ++++ l +k+ +++qe+ ke+ ++l ++ el++++++++++ k+ + e +ek++++e e +++++ FUN_001065-T2 1655 NEEVQGLEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSG 1748 2233333344444444444444444444444444444444445555555555555555555555555555555555555555555555555555 PP FKBP15 181 keslekslsdrkkk 194 ++l+k+l k + FUN_001065-T2 1749 LDHLKKELD-LKLR 1761 555555442.3333 PP == domain 14 score: -3.0 bits; conditional E-value: 2.4 FKBP15 12 IqrivqEN.erLkkevleksskieeqnekiseLleknqryvEqsn.lllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqle 103 I r EN e+Lk e+l k++ +k+s+ l +n ++E+ + +l+E+ + s k + e ek + +++L++a + s+l++ FUN_001065-T2 1780 ISRAAAENaECLKTEILAKENEL----HKVSQSLSSNMIMLEEIQaKLIESEKCSTKL--------KDDFELEKDDWKTRLEEAACENSSLKKG 1861 66666666456777777775544....4566666665555555441233333333222........2356788888899999999999999999 PP FKBP15 104 laalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrk...eleekltsleeeladlkaekeslekslsd 190 l+++++k+ l+++l+ +++++++++eele ++q + l+++v++l++ +kee +++ +l+ +++ + e+ +l+++ ++ + l+d FUN_001065-T2 1862 LSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHLQNVVKEEVLQSQkgeTLTDEIHAKKLEILELQKQLKQQQHLLND 1951 999999999999999999999999999999999999999999999999999986555401144455555556677777776666666666 PP == domain 15 score: 7.9 bits; conditional E-value: 0.0011 FKBP15 85 klteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlk 178 lt+e+ a + ++ elq++l+++q+ ++ + +++++++ s ++k++l+ +++ eel e+ + l+++ + ++ +l++ l+++ el + FUN_001065-T2 1923 TLTDEIHAKKLEILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMASELRRVS 2016 6899****************************************************************************************** PP FKBP15 179 aekeslekslsdrkkkaaeerkrleeeleelkks 212 +ek +le + d k k + ++l++ e+l ++ FUN_001065-T2 2017 QEKTELESDVFDLKDKLRSADRELDAIKEDLTNA 2050 **********999999988888777766666555 PP == domain 16 score: 3.8 bits; conditional E-value: 0.02 FKBP15 85 klteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkelee...kltsleeela 175 + +e +++ ++q+++l+++ ++l+ +e+q k +++++++ek+++el+ ++ +e+e+k+eel+++ e+K++ ++ee kl+++e FUN_001065-T2 2049 NASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKEREEDKERLSAAEEvfsKLQEMESFYG 2142 3344455666677777777777777777777777777777888888888899999999999999999999999887766652226777777788 PP FKBP15 176 dlkaekeslekslsd 190 lk+ekesl+ +l+d FUN_001065-T2 2143 ALKQEKESLKTELED 2157 999999999999998 PP == domain 17 score: 8.8 bits; conditional E-value: 0.00059 FKBP15 79 leqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqk 159 l qek +l++eL+ ++ l e+++e ++l + ++ l+s+++e e+ ++ele+l+++ +++e++v+ l++++ + q+ FUN_001065-T2 2144 LKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETNVTLLQNRISSMEQR 2224 667777777777777777777777777777777777777777777777777777777777777777777777766554444 PP == domain 18 score: -1.7 bits; conditional E-value: 0.96 FKBP15 59 EqrndslkstaeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqq 152 ++ n+++ s +q +++ +l+ ek +l +eL+++ ++l e+++ + ++ + ++kl+++ ++e ++ele+++++ +e+e+++++lkq+ FUN_001065-T2 2249 NEENSGFPSLEKQQVSQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQK 2342 57899999999********************************************************************************998 PP FKBP15 153 lkee...Kqkrkeleekltsleeeladlkaekes.lekslsdrkkkaaeerkrleeeleelkk 211 ee K++r + +e+l +eel+ +++ e + k +++ + e++++ee+l ++ + FUN_001065-T2 2343 HLEEnssKEERDKSDERLLFRQEELKLMQSYSEDvVTKRIEELTIAKELEKAQVEEKLTKQLQ 2405 766534488888999999999*******99766526889999999999999888887655433 PP == domain 19 score: -9.7 bits; conditional E-value: 10 FKBP15 27 leksskieeqnekiseLleknqryvEqsnlllEqrndslkstaeqsqarvleleqek........vklteeLaaataqlselqlelaa....lq 108 + k+ i ++++k+ e +e n++ + + + l + n ++t ++ ++++ ++e++k + l+++ ++ + l +l+l+la+ + FUN_001065-T2 2409 THKDGVIAKLKDKVREKIELNKKNIAEFKVKLANANKEKEETLQELHSQLANAEKDKkaaleelkLFLDNSQKEKDQALQDLELQLAKaiaeKE 2502 56777799************************************************96666665544455555666677777777655111145 PP FKBP15 109 kkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrk 192 + +elqs+l+ +q++e+ +++l++lr +++ + ++e lk++l + ++ k+ e k ++ +l++lk e e+ e++ + FUN_001065-T2 2503 EVVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEMD 2586 55689999999999*********************************************9999999999998888887665543 PP == domain 20 score: 0.8 bits; conditional E-value: 0.17 FKBP15 87 teeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklra.qveeleekveelkqqlkeeKqkrkeleekltsleeeladlka 179 +++++ ++ +s+l+++l++ + +++ +kl+ + +e++ + e+l+ +++ + e ++++++l+++ ++ K kr +le+ ++ e+e+ +lk+ FUN_001065-T2 2599 DKSITDRNKLISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQLKAMHEeELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKR 2692 33444455556666666666666666666666666666666666666554414457788999999999999*********************** PP FKBP15 180 ekeslekslsdrkkkaaeerkrleeeleelkk 211 + +++ k+ +d +++++ +k+lee+ + + FUN_001065-T2 2693 DLDEITKEKKDLERNHEQLKKELEEQETDFTS 2724 ****9997777777777777766665544444 PP == domain 21 score: -5.3 bits; conditional E-value: 10 FKBP15 107 lqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaaeerk 200 l+++e++++s +++++++ e+++ + e+l+ q l+e+v+e k++ +++++++ l ++++l e ++ lk++ + + + l++ + ++ee+ FUN_001065-T2 2715 LEEQETDFTSSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQTLKNKDQDIVR-LENELQLSQEEKL 2807 56667777777777777777777777777777777777777777777777777777777777777777777777666666.5555555566665 PP FKBP15 201 rleeeleelkk 211 +l e+l l++ FUN_001065-T2 2808 QLAEQLTSLNE 2818 55555554443 PP == domain 22 score: -1.3 bits; conditional E-value: 0.76 FKBP15 103 elaalqkkeaelqsklssalqesekqkeeleklraqveelee.....kveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdr 191 +l++++ + +e+q++l++a++ +ek k+++ ++++ + e +++++k+++ + +q++ +le+++ +l+eel ++ +ek+ + l+ + FUN_001065-T2 2906 DLHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSEsvrdvESSDMKAEIDKARQEKINLEKTALELREELVEIVREKDGTIGDLKQK 2999 45566667777777777777777777777765544444433301111345678889999*********************************** PP FKBP15 192 kkkaaeerkrleeeleelkksle 214 ++ +e++r e +e+ k l FUN_001065-T2 3000 IRQLLNEKSRNEVLVEKYEKLLA 3022 ********999877776665444 PP == domain 23 score: 3.0 bits; conditional E-value: 0.037 FKBP15 26 vleksskieeqnekiseLle...knqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqle.laalqkkeaelq 115 v ek+ i ++++ki +Ll+ +n+ +vE+ ++ll +r + +k+ +++ l ++ e+ + +++ + +le +++l++++ ++ FUN_001065-T2 2986 VREKDGTIGDLKQKIRQLLNeksRNEVLVEKYEKLLAERDEEIKRIGANADVEAQGLRDRCQHVLEDKEFLVKKIQQEKLEyVQELENTKDGYE 3079 779****************83334677**********************987666666555555555555555555555554678888888999 PP FKBP15 116 sklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrk 192 + ls +e + k el + + ++eel+ ++ +++++ e + + + ++ ++ l+ +l+ +ek +++ + + FUN_001065-T2 3080 KVLSDKDEEIGNFKRELVSCNIETEELKGRLRQTQESFDELNKLKVDFDHIISGLRGDLQQALEEKAVADQLAHEFR 3156 99999999999***********************************************9999999998888776655 PP == domain 24 score: 0.2 bits; conditional E-value: 0.27 FKBP15 101 qlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkk 194 q+e k++++l++kl++al+++ +k r++++ ++e ++e+ ++l ++++ e ++++++l+ el++ +eke++ + + + FUN_001065-T2 3261 QNE----LKQASDLNNKLKEALKKK------RSKPRSKSSGEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFVQEKERIVAGFKSKMEM 3344 222....233444444444444433......335566667777778888888999999999999999999999999999999999999999999 PP FKBP15 195 aaeerkrleeeleelkksle 214 a+e++r+++ +ee k+l FUN_001065-T2 3345 LADEKERANSLIEEYEKQLL 3364 99999999999999988875 PP == domain 25 score: -4.9 bits; conditional E-value: 9.7 FKBP15 12 IqrivqENerLkkevleksskieeqnekiseLle....knqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselq 101 +q vqEN +L ++ +s + e ++++seL + ++++++ + +++ E+ +l + +++ + +lel q + +l+++L++ + + + FUN_001065-T2 3401 LQLTVQENAELENDLRYNKSLVKESTDRVSELKRelesREEKHLKEIEEIKERHDQVLIAKQKETDEAILELRQINTELQDNLQSVSDNRDATE 3494 5778**************************98651212677899999999******************************************** PP FKBP15 102 lelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkka 195 +el ++ k l++ ++ + e++++++++l +q ee++ +++++ ql +++ +l+e++++le ++lk++ e++++++ ++ ++ FUN_001065-T2 3495 RELIGTRAK---LEQVVQDSYPVIEEKSQKIQELLSQMEENRINADNVIVQLE---RSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRF 3582 **9998866...56666666777777777888888888888888877776664...35567788888888888888888888888888888888 PP FKBP15 196 aeerkrleeeleelkksleeeiqsLrek 223 + ++ e el e k+ l++++q+L +k FUN_001065-T2 3583 QRSVEEKETELREEKEGLQQQMQQLEAK 3610 8888888888888888888888888766 PP == domain 26 score: 3.3 bits; conditional E-value: 0.03 FKBP15 66 kstaeqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeele.klraqveeleekveelkqqlkeeKq 158 ++ +++ q+ + ++e+++++ ++ + + + + s+lq+++++l+ ++el+++l+++ +e +kq+ + + +++++++el+e+ e l+qq+++ + FUN_001065-T2 3516 EEKSQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRFQrSVEEKETELREEKEGLQQQMQQLEA 3609 4566677777889999999999999999999999999999999999999999999999999888777624677778888888888888877655 PP FKBP15 159 krk....eleekltsleeeladlkaekeslekslsd...rkkkaaeerkrleeeleelkksleee 216 k + ++ +++leeela + e s +++l+ k+ +++ r+ +++ + l+ l++ FUN_001065-T2 3610 KFEellsQSQASISKLEEELAHTNMELVSFNEKLQTadgEKQDIEKLRNNFDHIISGLRGDLQQA 3674 54411115567788899999888888888877654322566666666666766666666666665 PP == domain 27 score: -2.7 bits; conditional E-value: 2 FKBP15 70 eqsqarvleleqekvklteeLaaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkee 156 +qsqa + +le+e ++ + eL + +++l +++ e + ++k ++++ +s + +++++ ++ + ++ ++e + ++e+++++ + FUN_001065-T2 3616 SQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRNNFDHIISGLRGDLQQAINARAAAEELAHEFQVQLEKMRKSNPTT 3702 678888888888888888888888888887777777777777766666666666666665555555555555555555555443333 PP == domain 28 score: -7.2 bits; conditional E-value: 10 FKBP15 100 lqlelaalqkkeaelqsklssalqesekqkeeleklraqv 139 + + l+a+q++ea+l++ l+++l e + +++l + + FUN_001065-T2 3717 VSEMLEATQREEANLRAALEATLIERDALQNRLRDFELVL 3756 4556777888888888888888877777777666654332 PP == domain 29 score: -14.3 bits; conditional E-value: 10 FKBP15 91 aaataqlselqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesl 184 ++++ ++ +l++el+++++ +++l++kl ++ ++ + + + + e+ + +el+++l + +q++ e e++ ++l+ el+ +ekes+ FUN_001065-T2 3802 SETEVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVK-------SDSGDEDSSVRNELQTELEKIRQEKLEREKTCQELRLELDTFVREKESI 3888 44455566666666666666666666666665554443.......3344567777788888888889999999999999999999999999999 PP FKBP15 185 ekslsdrkkkaaeerkrleeeleelkksleee 216 ++l+ r ++ ++ + +e+l ++++++ FUN_001065-T2 3889 TNELKRRIDELSAKNEKSNTLIEDLEAQVKQK 3920 99999999999888899998899888888775 PP == domain 30 score: 6.2 bits; conditional E-value: 0.0039 FKBP15 104 laalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkkaae 197 + + + +el+ ++++++++ek+++ +e+l+aqv++++ ++ el +++ + + ++ + +++l+ e adl aeke l + ++ k + e FUN_001065-T2 3882 VREKESITNELKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLLAEKEDLISQSKEHEKDSSE 3975 55667778999*********************************************************************99999999999999 PP FKBP15 198 erkrleeeleelkkslee 215 + +e+ +ee ++ l++ FUN_001065-T2 3976 LKVYYESLVEEYNSLLDK 3993 887777777776654443 PP == domain 31 score: -3.6 bits; conditional E-value: 3.7 FKBP15 91 aaataqlselqlelaalq.kkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleeklt 168 ++ ++ +l+++l++++ k ++el+++ ++ + + ++++++l++++ + ++ e+lk+qlk+ K++r ++ + + FUN_001065-T2 3992 DKKDRSIAHLENQLDEVTeKYKTELRATRDQHEGIILQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKH 4070 4555556666666665431335666666666666666666666666666666666666666666666666554433222 PP == domain 32 score: 5.6 bits; conditional E-value: 0.0059 FKBP15 98 selqlelaalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslek 186 e q +l++l+k + ++ +++ ++++ +++ e+l+++ +++++++++ l K+ +++le+ +++le el++ ++ k ++ k FUN_001065-T2 4098 HEFQVQLKHLEKVSGNSGTQFENVAVDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERETMKVNIGK 4186 44555555555555555555555555555555555555555555555555555555555555556666666666666655555555555 PP == domain 33 score: -8.2 bits; conditional E-value: 10 FKBP15 102 lelaalqkkeaelqsklssalqesekqkeeleklraqv......eeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesleksls 189 +e+++++ + ++q++l+++++ +e+ k++l++l ++ + +ee+ eel+++l + +q++ e e+ +++l+ +l+++ +eke+ + + FUN_001065-T2 4232 EEVQKVRDDWYKMQNELDKVKAVNERLKTKLKTLMRKRkggkveTSEEENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREKERRVVEHK 4325 4455555555667777888777777777777777655411111144567778888888888999999999999999999999999888777777 PP FKBP15 190 drkkkaaeerkrleeelee 208 r +++ +e++++++ le FUN_001065-T2 4326 TRMQQVLTEKEKVNNLLET 4344 7777777888888777765 PP == domain 34 score: 9.2 bits; conditional E-value: 0.00045 FKBP15 12 IqrivqENerLkkevleksskieeqnekiseLleknqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqle.. 103 +q++++E e+ + + k++ e + is L+e+ q++ ++ +++ Eq+ s + + ++ + +l+ +kvk + eL aat +l +l + FUN_001065-T2 4328 MQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEV-EQSLAQAMSENRNLNTVLEQLQLQKVKAERELHAATGELERLLEGdr 4420 3444444444444444444444455555555555555554444443.22222222222233334557888999999999999999988865333 PP FKBP15 104 ..laalqkkeaelqsklssalqesekqkeel.eklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekesleks 187 la+ +++ ++l+++ls ++++ + + +l +++++ v+e+++++++l+++l + ++k+le+++++ e+ ++d+ + + + + FUN_001065-T2 4421 piLAEKEQRISNLEAELSDLKESFDIEMRTLkDRYDVVVSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTNFDHI 4507 347889999999999999999998876655526788899999999999999999999999999999999999999988777766655 PP == domain 35 score: 4.9 bits; conditional E-value: 0.0096 FKBP15 117 klssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrk....kkaaeerkrleeel 206 ls ++e e+ ++++++ r+++ +lee+v l + +++ K e +e++++lee+++ l ae+ + ++l k +e rk+++ ++ FUN_001065-T2 4564 VLSDNEAEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEHATSMEQLVLEVnkagKERDEIRKEMQINM 4657 478889999999*************************************************999876555544444001134455567777788 PP FKBP15 207 eelkksleeeiqsLrekl 224 + + ++++e+++++e++ FUN_001065-T2 4658 DAAVMQSNKELDQMKEQY 4675 999999*********997 PP == domain 36 score: -13.3 bits; conditional E-value: 10 FKBP15 20 erLkkevleksskieeqnekise....Lleknqr..yvEq...snlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlselqlel 104 e+L e+ ek + ie++ + i++ L++k+++ + E+ + +llE n+ l++ + + e e+ ++kl+++ + l +l+le+ FUN_001065-T2 4687 EQLEGELSEKRQVIEKLSDEIGQfragLVNKSDEekLYEElqaNYQLLETGNNKLRQDLYLT---MKETENLRMKLKKDY---DQMLASLKLEV 4774 889999***************87333366654322244431113456666666666555443...345566666666654...45688999999 PP FKBP15 105 aalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlk...eeKqkrkeleekltsleeeladlkaekeslekslsdrkkka 195 ++ ++++ e ++ +++ e e+ + e+l ++ +e+ + e+ q++ ++ + el++ ++ l+ e++d + ek++l + d FUN_001065-T2 4775 EQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRTDgdaADDDEIVELKNEISLLRKECQDCRVEKDKLYDKFHDAVESL 4868 999999999999999888888888777777777777776555444444431113345566899999**************************** PP FKBP15 196 aeerkrleeeleelkksleeeiqsL 220 +e +r +e ++l ++ ee++++ FUN_001065-T2 4869 RKELERSLHEKDNLAQKTEETLKQN 4893 *****************99999875 PP == domain 37 score: -12.0 bits; conditional E-value: 10 FKBP15 19 NerLkkevleksskieeqnekiseLleknqryvEqsnlllEqrndslkstaeqsqa..rvleleqekvklteeLaaataqlselqlelaalqkk 110 e+ ++ +lek++ i +q + L++ +++++ + ++ + ++l++t +++ ++el +e l +e + + + +l ++ FUN_001065-T2 4774 VEQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETGQVTRETLQRTDGDAADddEIVELKNEISLLRKECQDCRVEKDKL---YDKFHDA 4864 57789999*****************************************99886541146666666666666655544433333...3445556 PP FKBP15 111 eaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsdrkkka 195 + l+++l+ +l+e+++ ++ e++ +q++el++++ e ++ l + K + e+ + +++l+ +aeke l+k+l++r ++ FUN_001065-T2 4865 VESLRKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQ---FEHIGKGWRNDLEAARAEKELLQKQLEERTSQS 4946 6678888888888888888888888888888888888888888877764...555566778999999*************98765 PP >> Laminin_II Laminin Domain II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 1.1 0.33 8.5e+02 28 83 .. 103 144 .. 63 161 .. 0.56 2 ! 6.8 3.3 0.0035 8.9 32 100 .. 160 228 .. 144 229 .. 0.81 3 ! 5.9 8.1 0.0069 18 4 84 .. 212 288 .. 209 302 .. 0.87 4 ? -0.9 2.2 0.86 2.2e+03 48 93 .. 361 410 .. 322 427 .. 0.72 5 ? -3.6 6.2 5.8 1.5e+04 21 83 .. 418 477 .. 400 486 .. 0.61 6 ? 1.8 8.5 0.12 3.2e+02 20 97 .. 519 597 .. 504 601 .. 0.73 7 ? -6.6 7.2 10 2.6e+04 13 74 .. 695 752 .. 684 791 .. 0.53 8 ? -6.1 9.9 10 2.6e+04 28 80 .. 791 843 .. 760 866 .. 0.45 9 ? -5.4 8.3 10 2.6e+04 17 65 .. 815 860 .. 802 909 .. 0.64 10 ? 0.2 6.4 0.39 1e+03 16 99 .. 895 975 .. 871 986 .. 0.56 11 ? 5.3 6.3 0.01 26 4 84 .. 1009 1089 .. 1006 1099 .. 0.92 12 ! 6.2 8.9 0.0056 14 4 97 .. 1135 1225 .. 1132 1230 .. 0.86 13 ? 1.7 2.9 0.13 3.4e+02 2 76 .. 1224 1298 .. 1223 1313 .. 0.85 14 ? -0.5 8.7 0.61 1.6e+03 7 84 .. 1306 1380 .. 1282 1391 .. 0.60 15 ? -0.9 9.5 0.82 2.1e+03 8 100 .. 1388 1484 .. 1370 1485 .. 0.64 16 ! 7.0 2.9 0.0031 7.8 2 75 .. 1473 1543 .. 1472 1545 .. 0.80 17 ! 6.1 9.3 0.0057 15 8 96 .. 1539 1624 .. 1525 1626 .. 0.69 18 ? -0.7 3.6 0.75 1.9e+03 10 84 .. 1635 1709 .. 1626 1716 .. 0.77 19 ? -0.5 8.9 0.62 1.6e+03 12 82 .. 1686 1756 .. 1663 1782 .. 0.63 20 ? -5.0 8.0 10 2.6e+04 15 97 .. 1858 1909 .. 1814 1929 .. 0.49 21 ? 3.0 6.6 0.052 1.3e+02 19 96 .. 1935 2013 .. 1923 2015 .. 0.85 22 ! 19.2 8.6 5.3e-07 0.0014 3 91 .. 2003 2092 .. 2002 2099 .. 0.90 23 ! 6.2 9.7 0.0054 14 5 92 .. 2127 2218 .. 2121 2224 .. 0.78 24 ? -1.9 9.9 1.7 4.4e+03 17 86 .. 2264 2333 .. 2258 2343 .. 0.81 25 ? -2.8 2.8 3.3 8.4e+03 14 58 .. 2421 2466 .. 2411 2500 .. 0.65 26 ? -1.2 8.9 1 2.6e+03 5 81 .. 2498 2574 .. 2494 2595 .. 0.86 27 ? -1.2 11.0 1 2.6e+03 7 93 .. 2633 2716 .. 2624 2719 .. 0.82 28 ? -4.8 16.5 10 2.6e+04 12 100 .. 2694 2783 .. 2683 2788 .. 0.83 29 ? -6.7 14.4 10 2.6e+04 17 83 .. 2724 2790 .. 2709 2832 .. 0.60 30 ? -2.6 7.9 2.7 7e+03 19 84 .. 2914 2991 .. 2902 3012 .. 0.50 31 ? 2.1 0.7 0.099 2.5e+02 11 84 .. 3056 3126 .. 3042 3144 .. 0.68 32 ? -4.4 0.2 10 2.6e+04 66 79 .. 3265 3279 .. 3245 3289 .. 0.47 33 ? 3.1 1.3 0.05 1.3e+02 26 84 .. 3335 3393 .. 3322 3403 .. 0.83 34 ? -1.3 2.2 1.1 2.8e+03 9 70 .. 3423 3481 .. 3413 3499 .. 0.69 35 ? -0.0 9.8 0.45 1.2e+03 5 97 .. 3483 3573 .. 3479 3581 .. 0.82 36 ? 5.1 3.5 0.012 30 12 69 .. 3601 3658 .. 3588 3677 .. 0.82 37 ? -1.9 0.1 1.7 4.3e+03 13 63 .. 3679 3730 .. 3667 3750 .. 0.67 38 ? -6.6 8.8 10 2.6e+04 14 96 .. 3778 3861 .. 3770 3864 .. 0.72 39 ? -1.8 6.7 1.6 4.2e+03 12 78 .. 3882 3948 .. 3862 3977 .. 0.59 40 ? -0.9 5.3 0.82 2.1e+03 5 95 .. 3984 4075 .. 3981 4088 .. 0.53 41 ? 1.8 2.4 0.12 3e+02 14 68 .. 4120 4174 .. 4092 4187 .. 0.67 42 ? 0.2 2.3 0.37 9.5e+02 9 45 .. 4231 4267 .. 4226 4313 .. 0.74 43 ? 0.5 10.6 0.32 8.1e+02 16 95 .. 4311 4390 .. 4295 4403 .. 0.79 44 ? 2.4 1.6 0.079 2e+02 29 88 .. 4451 4504 .. 4420 4518 .. 0.65 45 ? -0.8 2.5 0.79 2e+03 17 81 .. 4570 4635 .. 4561 4654 .. 0.72 46 ? -3.0 6.3 3.7 9.4e+03 30 95 .. 4650 4710 .. 4619 4717 .. 0.43 47 ? -2.6 0.2 2.8 7.3e+03 30 79 .. 4764 4813 .. 4739 4849 .. 0.66 48 ? -0.6 1.3 0.69 1.8e+03 9 46 .. 4883 4920 .. 4875 4947 .. 0.78 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.33 Laminin_II 28 ntkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqlee 83 n +++++++ +++ +e++ d+ k+l + + v+ Le q+ FUN_001065-T2 103 NPVQNIQHVQVLLAQKDEVIGDLEKQLHESEAHVRRLE--------------QQGR 144 22333444444444444444444444444444444444..............4433 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0035 Laminin_II 32 klseinrsveetnekvkdankalr...dArrsvkkLeklapqLldklkelkqleeassslsdniseikelIa 100 +++++ ++eet+++++d nk+++ d ++ k L ++ +q++d+lk +k+l ++ + + ++e+I+ FUN_001065-T2 160 AAEGFQLKLEETKQLLEDRNKTVEglmDRLDAQKRLIETRDQVIDQLKAMKNLDSG---ADELVGTLREQIE 228 5789999**********99987652227778899*********************9...4577888888886 PP == domain 3 score: 5.9 bits; conditional E-value: 0.0069 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 l + a+e + eq++++++++e+ +++ +++r++ +++++++++ +++A+ kLe++ Ll +++e+++ +++ FUN_001065-T2 212 LDSGADELVGTLREQIEAMNTRVEKSVDEAGRAKREISALKKELEEKSELIASAE----KLEQEKSSLLMQIQEIEKEHKQ 288 5567899999999**************************************9996....8***************998776 PP == domain 4 score: -0.9 bits; conditional E-value: 0.86 Laminin_II 48 kdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdnis 93 + + k++++ +++vk+ e+ + L +k++ l++ ++ + s l+++i+ FUN_001065-T2 361 SHSDKVMALLEEKVKEREEMIRSLSEKMNFLEKGSVDKTSeidfLKKSID 410 467889999999****************9999999998766666444443 PP == domain 5 score: -3.6 bits; conditional E-value: 5.8 Laminin_II 21 plsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqlee 83 l++ l+ +++ +i+++ + +++++ + l + +s +L+k + L d l+el+ +e+ FUN_001065-T2 418 VLQETLQAKDQEIAGIKEK---HETEMSEKEMKLSSQIKSNEELQKMVASLKDSLSELESKEK 477 3333444444444444444...55556677777777777777777777777777777777765 PP == domain 6 score: 1.8 bits; conditional E-value: 0.12 Laminin_II 20 aplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdniseike 97 ++s +l + +++++ +++ ++++ ++ k + A+ +v L+++ ++L + ++el+++ ++ + ++is+i e FUN_001065-T2 519 SKMSDELIEARAEIEAKEKE---VKDLNSKIGKLKLQAKAKVTGLQNEKEKLSKEMQELEMHLLHEREeklaIQKKISQIEE 597 44555555555555544444...33333344566689************************99987777899*******975 PP == domain 7 score: -6.6 bits; conditional E-value: 10 Laminin_II 13 kevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldk 74 ++v+e + l+++ e+ ++k++ei ++ ++ +++ +a ++ v L+++ + L FUN_001065-T2 695 SKVEELEEMLEAEKEQQQKKAEEISSD----EDAEHAKHMAEESLMMHVEALQEENETLRVS 752 455555555556666666666666555....4455555566666666666666555555433 PP == domain 8 score: -6.1 bits; conditional E-value: 10 Laminin_II 28 ntkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkq 80 ++kek + +++e +++ ++++ ++ +r+ + ++ L+ +l++ q FUN_001065-T2 791 EEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQKRSAVETLERQLQQSTQ 843 34444444444433333333333333333333333333333333333332222 PP == domain 9 score: -5.4 bits; conditional E-value: 10 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLe 65 + ++ l+ +le+ ++ +++++r+ ++ ++ nk+l+d +++++L+ FUN_001065-T2 815 QNVETLERELEQKRSAVETLERQ---LQQSTQERNKVLEDKDKEISNLQ 860 45666666666666666666666...34444456666666666666654 PP == domain 10 score: 0.2 bits; conditional E-value: 0.39 Laminin_II 16 leqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseikelI 99 ++ ++ l++++++ ++ ++++ s + + v++++ l+d ++ k ++ ++ + l++l ++++ ls++++e++ + FUN_001065-T2 895 EAEVERLQKEMSEQEAGHEQLKLSYTGVCATVSEMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDE---LSNEVQELRTVV 975 444555555555555555555555444455555555555555555555555555555554444444444...667777666655 PP == domain 11 score: 5.3 bits; conditional E-value: 0.01 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 +++ +e++++ ++ l+ + n ++ ++++ + + + e ++ +++al+ +++v +L+ ++++ ++ lk l ++ e+ FUN_001065-T2 1009 QLKDLEEIVQAKESELNSMRSNFDEQANSYKDLTQVISENATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEE 1089 678899*****************************************************************9999988776 PP == domain 12 score: 6.2 bits; conditional E-value: 0.0056 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++e n+++++ +e+ ++l++nl++ + ++++ ++ + ++k++d++k l + v++Le+++ ++++ ++l+ ++ ni+ +k+ FUN_001065-T2 1135 SVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENTLKEIEKSHQQLESELNE---ANGNIDGMKN 1225 6899****************************************************************9998888765544...3456665555 PP == domain 13 score: 1.7 bits; conditional E-value: 0.13 Laminin_II 2 kelaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklk 76 k+ +a+ +e ++ e++ +l+ + e++k + se+ ++++e ++++ + + l r+sv + +qL ++l FUN_001065-T2 1224 KNDIANKDEEIVTLTEKVGALNLDYEEMKTSFSEASSQMRELHDLLTLKETELTVLRTSVENQGSSHQQLTSRLA 1298 56677778888888999999***************************9999999999999999999999988864 PP == domain 14 score: -0.5 bits; conditional E-value: 0.61 Laminin_II 7 eanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 e t+++ ++q+ l+ ++e t ++++ +++ n +v ++++++++ +++ L ++ +L+ + +el++++e+ FUN_001065-T2 1306 ELTITLSNKEDQISSLERDVEATLQQYKDLESR---HNSDVLKLKETIAEKESENASLCSEVKELVFRASELNTRNEE 1380 333445555566666666666666666666666...566666666666666666666666666666666666666555 PP == domain 15 score: -0.9 bits; conditional E-value: 0.82 Laminin_II 8 anetakevleqlaplsqnlentkeklseinrsveetnekvk....dankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++ +e ++ l +l++ le+ + l+++++s+++t+ +v + + l+d ++s ++ +qL + ++l ++ee+s+ l++n++e + FUN_001065-T2 1388 LQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLrlqsILDEKLADLEESRMGFAENSNQLNELRERLRNKEEESNLLKANVEERNA 1481 2233333344444555556666666667777777777766523223455666777787788888888888888899999997779999998666 PP Laminin_II 98 lIa 100 +++ FUN_001065-T2 1482 IVE 1484 665 PP == domain 16 score: 7.0 bits; conditional E-value: 0.0031 Laminin_II 2 kelaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldkl 75 k++++e n ++++ ++ la++s n+ ++ e ls n++v+ n ++ + + v++L+ ++ L ++l FUN_001065-T2 1473 KANVEERNAIVEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMSLS---EECFYFDSRVSELQDKVGALQEQL 1543 899***********************************888776554...555555566677766666666665 PP == domain 17 score: 6.1 bits; conditional E-value: 0.0057 Laminin_II 8 anetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseik 96 +e+++e +e +++l+ l++ ++++s++++s+ t +++d+ +l++ + ++k+a+ L + ++ ++++++ ++++e++ FUN_001065-T2 1539 LQEQLAEKEEEIQALESSLDERSQSISNLDTSLTDTSTQLEDLRSQLASKDGKFAAMKKKAQALKKS---YENAVSENENIQKELDELR 1624 4566667777777888888888888888888888888888888888888888888888888777555...3444444444888888877 PP == domain 18 score: -0.7 bits; conditional E-value: 0.75 Laminin_II 10 etakevleqlaplsqnlentkeklseinrsveetnekvk.dankalrdArrsvkkLeklapqLldklkelkqleea 84 + +++ l ql + +++l+ +e+++++++++ +e ++ ++n+ +A +v +L++++ L ++ ++l +++ FUN_001065-T2 1635 DAMEKCLTQLIEHKNQLQAKNEEVQGLEKKLGVADESLQiSSNEKETLA-AKVIELQQELGLLKEQTQRLIDERDE 1709 5667788888888999999999999999999999999996666666666.57899999999999998888666665 PP == domain 19 score: -0.5 bits; conditional E-value: 0.62 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqle 82 + e ++ l l+++++++ ++ e+++++++t+++ k++ + +++ +++++++e + +++ + l +lk+ FUN_001065-T2 1686 VIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKEL 1756 33444555555666666666666666666666666666666666666666666666666666666666543 PP == domain 20 score: -5.0 bits; conditional E-value: 10 Laminin_II 15 vleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++ l ++ ++ + + +l+ ++++++ + +el++++++ s l +++s +++ FUN_001065-T2 1858 LKKGLSEMTEKQDSLTTQLNVSQKDLKRSQ-------------------------------EELEMKNNQLSTLQAEVSHLQN 1909 222222222222222222222222222222...............................3333333333333333333322 PP == domain 21 score: 3.0 bits; conditional E-value: 0.052 Laminin_II 19 laplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.lsdniseik 96 + +l+++l++ + l+ +++v e n++ + +kal+ A++ + +L + + L++ + + + ++ ++ ls+ se++ FUN_001065-T2 1935 ILELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQAnLSEMASELR 2013 4589****************************************************97666666665555888888777 PP == domain 22 score: 19.2 bits; conditional E-value: 5.3e-07 Laminin_II 3 elaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.lsdn 91 ++++e + + v + +++l+ +++ +k+kl +++r+++ ++e++ +a++++ ++++k Lek L++ l+e++ +e++ + l + FUN_001065-T2 2003 ANLSEMASELRRVSQEKTELESDVFDLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKdLEKT 2092 57788999999******************************************************************9999955555554 PP == domain 23 score: 6.2 bits; conditional E-value: 0.0054 Laminin_II 5 aaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdni 92 a+e+ ++++e ++ +l+q+ e +k +l+ +n+ ++e++ + ++ l+ A + L+++ +q+ + l++lk+ + s+ l + i FUN_001065-T2 2127 AEEVFSKLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKELSDSETnvtlLQNRI 2218 66777788888888888888888999999999999999998888999999999999999999999999999999888777654455444444 PP == domain 24 score: -1.9 bits; conditional E-value: 1.7 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeass 86 +q+++l+ + +n+ ++l e ++++e++e + l+dA+++ +L + + + + l+++kq ++++ FUN_001065-T2 2264 SQMEQLQLEKDNLVAELTETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQE 2333 5677888888888888888888888888888899999**************************9877644 PP == domain 25 score: -2.8 bits; conditional E-value: 3.3 Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvk.dankalrdAr 58 +v e+++ ++n+ + k kl ++n++ eet ++++ ++ +a +d + FUN_001065-T2 2421 KVREKIELNKKNIAEFKVKLANANKEKEETLQELHsQLANAEKDKK 2466 5555555566778888888888888766666655533333333333 PP == domain 26 score: -1.2 bits; conditional E-value: 1 Laminin_II 5 aaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkql 81 +ae +e ++e ++ql+ sq +e++++ l +++++ + t ++++ ++ l+dA+++ k+ e + ++ l+ l++lk FUN_001065-T2 2498 IAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRDNNRVTVDELEGLKRKLVDAENEGKQKELKWQEALSDLQNLKLE 2574 678899999******9999****************9*******************9999888888888888877754 PP == domain 27 score: -1.2 bits; conditional E-value: 1 Laminin_II 7 eanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdnis 93 ++ e+ ++v++ +a +++l ++ +++++++++ + ++k +++ + A++++ +L++ ++++ + k l+ +e+ l+++++ FUN_001065-T2 2633 SIAEKDANVEQLKAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKRDLDEITKEKKDLERNHEQ---LKKELE 2716 56677788888888888899999999999999977777778888888999**************99887788777777...888776 PP == domain 28 score: -4.8 bits; conditional E-value: 10 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss....lsdniseikelIa 100 + e+ + +++l+ n e++k++l+e +++ + v++++ + + A r+ +L+ +++ L + ++e k e++++ l d+++++ e ++ FUN_001065-T2 2694 LDEITKEKKDLERNHEQLKKELEEQETD---FTSSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEekqlLVDQVQQLSEAVQ 2783 4567788888888888888888888888...89999999*********************999988888888877778888999998877765 PP == domain 29 score: -6.7 bits; conditional E-value: 10 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqlee 83 + + +ls + en k +e++ +++ ne+v++++ + +++ + L +++qL + +++lk++ + FUN_001065-T2 2724 SSVDALSSQRENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQTLKNKDQ 2790 4444555555555555555555555555555555555555555555555555555555555554443 PP == domain 30 score: -2.6 bits; conditional E-value: 2.7 Laminin_II 19 laplsqnlentkeklseinrsveetnekvk............dankalrdArrsvkkLeklapqLldklkelkqleea 84 l++++++l + k+ ++++++v+ +k + d++ ++ Ar++ +Lek+a +L + l e+ +++ FUN_001065-T2 2914 LKEIQAELTKAKALNEKLKAKVRVFMKKERaksesvrdvessDMKAEIDKARQEKINLEKTALELREELVEIVREKDG 2991 445555555555444444444444433333000001111122455556666666667777777777776666555555 PP == domain 31 score: 2.1 bits; conditional E-value: 0.099 Laminin_II 11 takevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 +k++++ + + q+lentk+ ++++ ++ +e++ +++ l++ + + +L+ + q + + el++l++ FUN_001065-T2 3056 LVKKIQQEKLEYVQELENTKDGYEKVLSD---KDEEIGNFKRELVSCNIETEELKGRLRQTQESFDELNKLKVD 3126 46777777777777777777777777776...566677777777777777777777777777777777776665 PP == domain 32 score: -4.4 bits; conditional E-value: 10 Laminin_II 66 klapqLldklke.lk 79 k+a +L +klke lk FUN_001065-T2 3265 KQASDLNNKLKEaLK 3279 233334444432233 PP == domain 33 score: 3.1 bits; conditional E-value: 0.05 Laminin_II 26 lentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleea 84 + k+k++ ++++ e+ n +++++ k+l+ ++v++L+ + + L + lk e+ FUN_001065-T2 3335 VAGFKSKMEMLADEKERANSLIEEYEKQLLTKDTAVRDLTVKFDLLSSENDALKSDVEN 3393 6678999999****9***************************99998877777766555 PP == domain 34 score: -1.3 bits; conditional E-value: 1.1 Laminin_II 9 netakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapq 70 +e++ v e + +l+ + e+ ++++ei++ ++++ +++k +++A + ++++ ++++ FUN_001065-T2 3423 KESTDRVSELKRELESREEKHLKEIEEIKER---HDQVLIAKQKETDEAILELRQINTELQD 3481 4566666666666666666666666666666...5555568888888888888888877654 PP == domain 35 score: -0.0 bits; conditional E-value: 0.45 Laminin_II 5 aaeanetakevleqlaplsqnlent.keklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseike 97 ++++++ ++++ l + ++le++ ++++ i+++ ++++e+++++ + A + +++Le+ L ++++el+ + + l+ +++e ++ FUN_001065-T2 3483 LQSVSDNRDATERELIGTRAKLEQVvQDSYPVIEEKSQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTE---LKTQLEETRA 3573 56666667777777778888887752778999999************************************8888888877...8888888775 PP == domain 36 score: 5.1 bits; conditional E-value: 0.012 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklap 69 ++ ++ a+ ++ l++ ++++s++++++++tn ++ ++n+ l+ A + +++ekl + FUN_001065-T2 3601 QQQMQQLEAKFEELLSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRN 3658 4556666677777889999***************************999988888755 PP == domain 37 score: -1.9 bits; conditional E-value: 1.7 Laminin_II 13 kevleqlaplsqnlentkeklseinrsveetnekvk.dankalrdArrsvkk 63 ++ +e ++ +++le+++++ + +++v+e+ + + +++l+ +r+ + FUN_001065-T2 3679 AAAEELAHEFQVQLEKMRKSNPTTANEVDEISPPQEnKVSEMLEATQREEAN 3730 5567778888899999999988888888888765542444444444444445 PP == domain 38 score: -6.6 bits; conditional E-value: 10 Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.....lsdniseik 96 +v+++++++ + + + +++s++ +s et+ +++++++ l+ +++ kL+ ++ +++k +++k + + s l ++++i+ FUN_001065-T2 3778 NVQKVVEEVILQSS-EDNQVSSLPTS--ETEVEIENLKNELQRVKNVNEKLKAKLRTMMKK-RRVKSDSGDEDSsvrneLQTELEKIR 3861 67777777766644.45667777777..888888888888888888888888888888888.88887776655566666777777776 PP == domain 39 score: -1.8 bits; conditional E-value: 1.6 Laminin_II 12 akevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkel 78 + e ++++++l+ +++++++k ++ n+ +e +++vk++ +l++ v+ +e+ +q + +++l FUN_001065-T2 3882 VREKESITNELKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETL 3948 3344455555555555555555555555555555555555555555555555555555544444433 PP == domain 40 score: -0.9 bits; conditional E-value: 0.82 Laminin_II 5 aaeanetakevleqlaplsqnlentkeklseinrsveetnekvk.dankalrdArrsvkkLeklapqLldklkelkqleeassslsdnisei 95 ++e n+ + + + +a l+++l+++ ek+++ r + +e + + + + +++ k+ +qL ++lk k+ +e + l++n + i FUN_001065-T2 3984 VEEYNSLLDKKDRSIAHLENQLDEVTEKYKTELRATRDQHEGIIlQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHI 4075 55566666666666667777777777776643333343343333133333333333333334566777777777777776666666664443 PP == domain 41 score: 1.8 bits; conditional E-value: 0.12 Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLekla 68 +v ++ +++++ e+++ekl ++++++++ + ++ +++ + +++v +Le+++ FUN_001065-T2 4120 NVAVDTSDIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLEREL 4174 5555566666666666666666666666666666655555555566666665554 PP == domain 42 score: 0.2 bits; conditional E-value: 0.37 Laminin_II 9 netakevleqlaplsqnlentkeklseinrsveetne 45 ne +++v ++ +++++l+++k+ ++++++++ FUN_001065-T2 4231 NEEVQKVRDDWYKMQNELDKVKAVNERLKTKLKTLMR 4267 8999*********************999999765544 PP == domain 43 score: 0.5 bits; conditional E-value: 0.32 Laminin_II 16 leqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeassslsdnisei 95 e++ + + ++ + k ++++ ++ e++n++++ + k l++ +++ L ++++ L dkl+e++q + s +n++ + FUN_001065-T2 4311 DEIVREKERRVVEHKTRMQQVLTEKEKVNNLLETKEKLLLERDAAISSLVEQIQSLGDKLHEVEQSLAQAMSENRNLNTV 4390 56677777888899999999999999999999999999999999999999999999999999999887755544444444 PP == domain 44 score: 2.4 bits; conditional E-value: 0.079 Laminin_II 29 tkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasssl 88 +k+ + + v e +++++++ +l + +++ k+Le + +d ++ +++l+ + FUN_001065-T2 4451 LKDRYDVV---VSEQQKHINNLESTLGSLNTEKKQLESRVKAFEDGIEDINKLRTN---F 4504 33333333...445788888888888888999999999999999999999998888...3 PP == domain 45 score: -0.8 bits; conditional E-value: 0.79 Laminin_II 17 eqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldk.lkelkql 81 + +++l++ + + +e+ ++++v +++v+d + l + ++++++Le+ +++L + +++ql FUN_001065-T2 4570 AEIEDLQTAVAQFREEKYDLEEQVLALDKVVQDGKGDLMEKQEQIQTLEEDIERLAAEhATSMEQL 4635 567888888888888888899998889999999888888889999999998888864313445555 PP == domain 46 score: -3.0 bits; conditional E-value: 3.7 Laminin_II 30 kekls.einrsveetnekvkdanka.lrdArrsvkkLeklapqLldklkelkqleeassslsdnisei 95 +++++ ++++ v + n+++++++++ +++ ++s kk+e+l +L +k + ++ lsd+i + FUN_001065-T2 4650 RKEMQiNMDAAVMQSNKELDQMKEQyTLLKENSAKKMEQLEGELSEKRQVIE-------KLSDEIGQF 4710 2222113334444445555443333134444555555555555555533333.......466666655 PP == domain 47 score: -2.6 bits; conditional E-value: 2.8 Laminin_II 30 keklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelk 79 + l +++ +ve+ ++ ++ k + r +v L + + L+ kl+e FUN_001065-T2 4764 DQMLASLKLEVEQSRQQNLEKEKFIHNQRIEVESLVRDKESLITKLRETG 4813 33445556666666676677778888888888888888888888887654 PP == domain 48 score: -0.6 bits; conditional E-value: 0.69 Laminin_II 9 netakevleqlaplsqnlentkeklseinrsveetnek 46 ++++e+l+q +l+q l + ++ l +++ + e++ + FUN_001065-T2 4883 AQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHIGKG 4920 578999999**********9999999999888777665 PP >> ERM_helical Ezrin/radixin/moesin, alpha-helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.0 2.6 10 2.6e+04 66 97 .. 50 81 .. 40 85 .. 0.46 2 ? -0.8 11.9 0.86 2.2e+03 18 92 .. 118 196 .. 109 205 .. 0.68 3 ? -11.0 28.3 10 2.6e+04 13 108 .. 232 331 .. 223 343 .. 0.57 4 ? -7.3 16.2 10 2.6e+04 27 91 .. 372 447 .. 362 476 .. 0.41 5 ? -12.9 23.9 10 2.6e+04 1 113 [. 434 553 .. 434 558 .. 0.60 6 ? -8.9 28.9 10 2.6e+04 12 116 .. 508 616 .. 497 640 .. 0.67 7 ? -2.5 15.5 2.8 7.1e+03 37 98 .. 670 733 .. 666 734 .. 0.83 8 ? -7.5 33.3 10 2.6e+04 8 116 .. 732 841 .. 721 845 .. 0.80 9 ? -4.2 28.5 9.8 2.5e+04 14 116 .. 784 908 .. 782 919 .. 0.72 10 ! 5.8 14.0 0.0073 19 10 114 .. 928 1032 .. 924 1037 .. 0.94 11 ? -2.7 11.9 3.2 8.1e+03 33 111 .. 1049 1127 .. 1029 1134 .. 0.57 12 ! 18.3 9.7 1e-06 0.0026 4 113 .. 1132 1241 .. 1127 1248 .. 0.96 13 ? -1.2 3.6 1.1 2.8e+03 41 115 .. 1257 1327 .. 1245 1332 .. 0.74 14 ! 5.6 14.5 0.0089 23 24 112 .. 1345 1433 .. 1324 1440 .. 0.89 15 ? 1.7 14.2 0.14 3.7e+02 40 112 .. 1435 1517 .. 1432 1537 .. 0.55 16 ? -5.4 24.1 10 2.6e+04 10 118 .. 1538 1653 .. 1530 1655 .. 0.82 17 ! 13.5 16.7 3e-05 0.077 18 113 .. 1661 1756 .. 1654 1764 .. 0.93 18 ? -2.0 15.2 1.9 4.9e+03 23 117 .. 1817 1908 .. 1797 1913 .. 0.77 19 ? -0.6 17.1 0.71 1.8e+03 16 119 .. 1936 2039 .. 1927 2040 .. 0.91 20 ? -0.6 27.7 0.73 1.9e+03 5 117 .. 2023 2135 .. 2019 2138 .. 0.90 21 ? 1.4 22.6 0.17 4.4e+02 20 115 .. 2111 2206 .. 2104 2210 .. 0.89 22 ? -4.5 23.9 10 2.6e+04 10 119 .. 2282 2397 .. 2273 2398 .. 0.85 23 ? -11.6 28.4 10 2.6e+04 37 118 .. 2442 2531 .. 2416 2533 .. 0.61 24 ? -10.0 20.8 10 2.6e+04 18 110 .. 2550 2645 .. 2536 2648 .. 0.48 25 ? 5.0 19.1 0.014 35 22 96 .. 2645 2719 .. 2639 2727 .. 0.88 26 ! 8.2 27.7 0.0013 3.4 1 105 [. 2733 2833 .. 2733 2845 .. 0.87 27 ? -5.3 16.2 10 2.6e+04 15 99 .. 2907 2989 .. 2903 2992 .. 0.85 28 ? -2.7 13.5 3.2 8.1e+03 17 103 .. 2956 3039 .. 2954 3054 .. 0.84 29 ! 11.8 1.3 0.00011 0.28 3 97 .. 3070 3164 .. 3069 3171 .. 0.93 30 ? -11.6 15.0 10 2.6e+04 26 92 .. 3261 3328 .. 3237 3374 .. 0.45 31 ? -11.5 19.4 10 2.6e+04 25 116 .. 3407 3507 .. 3400 3511 .. 0.70 32 ? -9.9 33.7 10 2.6e+04 4 97 .. 3515 3609 .. 3514 3613 .. 0.81 33 ! 6.1 12.8 0.0061 16 3 108 .. 3603 3708 .. 3601 3716 .. 0.94 34 ? -2.2 0.3 2.3 5.9e+03 67 94 .. 3721 3748 .. 3710 3764 .. 0.45 35 ? -4.2 19.2 9.5 2.4e+04 19 113 .. 3805 3899 .. 3802 3906 .. 0.86 36 ? -10.4 16.2 10 2.6e+04 11 101 .. 3892 3982 .. 3889 4024 .. 0.54 37 ? 3.2 11.0 0.047 1.2e+02 13 108 .. 4003 4092 .. 3992 4108 .. 0.66 38 ? 5.3 12.0 0.01 27 3 54 .. 4127 4178 .. 4125 4190 .. 0.86 39 ? -8.7 23.1 10 2.6e+04 16 113 .. 4235 4331 .. 4230 4338 .. 0.68 40 ? -1.8 12.6 1.7 4.3e+03 11 91 .. 4359 4443 .. 4351 4473 .. 0.71 41 ! 12.1 2.7 8.5e-05 0.22 6 111 .. 4478 4598 .. 4474 4607 .. 0.91 42 ? -1.9 8.5 1.8 4.7e+03 37 86 .. 4605 4654 .. 4595 4663 .. 0.79 43 ? 0.1 10.7 0.44 1.1e+03 52 98 .. 4660 4706 .. 4647 4721 .. 0.85 44 ? -10.9 15.5 10 2.6e+04 6 114 .. 4750 4862 .. 4716 4868 .. 0.62 45 ? -4.7 22.9 10 2.6e+04 8 115 .. 4854 4971 .. 4848 4975 .. 0.69 Alignments for each domain: == domain 1 score: -5.0 bits; conditional E-value: 10 ERM_helical 66 rLeesaekeekekeqlerelaeaeeeiarlee 97 +L es +++e ++ ++ l+++eee+ +l+e FUN_001065-T2 50 ALSESEMRNEGINREFQKLLRQKEEELVQLRE 81 34444444444444444444444444444444 PP == domain 2 score: -0.8 bits; conditional E-value: 0.86 ERM_helical 18 yeeetkkaqeeLeeseetaeeLeekrreaeee.aerLeqkrqeaeeekerLeesaekee.kek..eqlerelaeaeeei 92 e + +++L+ese ++Le++ r ee+ + +L+ k ++ae +Lee+++ e ++k e l+++l++ ++ i FUN_001065-T2 118 KDEVIGDLEKQLHESEAHVRRLEQQGRDNEEKvMHELAVKIRAAEGFQLKLEETKQLLEdRNKtvEGLMDRLDAQKRLI 196 5556666788999999999999999999988734588888888888888888877543202222255555555555555 PP == domain 3 score: -11.0 bits; conditional E-value: 10 ERM_helical 13 erLkqyeeetkkaqee...LeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek.eqlerelaeaeeeiarleeekerkee 104 r ++ +e+ +a++e L+++ e + eL ++++e+e+ L + qe+e+e ++ + + + +ek ++l+ e aeae+ ++ e + +++ + FUN_001065-T2 232 TRVEKSVDEAGRAKREisaLKKELEEKSELIASAEKLEQEKSSLLMQIQEIEKEHKQTVLRLQHDVEEKeKALAVEFAEAEQVYKTNEHDLRERLD 327 455555555555554322267777777777777777777777776666666666555333333333333146888888888888777766555555 PP ERM_helical 105 eaer 108 e + FUN_001065-T2 328 EKAQ 331 5444 PP == domain 4 score: -7.3 bits; conditional E-value: 10 ERM_helical 27 eeLeeseetaeeLeekrreaeee...........aerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeee 91 e +e ee++++L ek+ +e+ ++ + k++ ++ e L+ + ++ + ke+ e+e+ e+e++ FUN_001065-T2 372 EKVKEREEMIRSLSEKMNFLEKGsvdktseidflKKSIDDKASTIKVLQETLQAKDQEIAGIKEKHETEMSEKEMK 447 2233333333333333333332211111111111233333444444444444444444444444444444444444 PP == domain 5 score: -12.9 bits; conditional E-value: 10 ERM_helical 1 reeaerekqeleerLk...qyeeetkkaqeeLeese...etaeeLeekrreaeeeaerL.eqkrqeaeeekerLeesaekeekekeqlerelaeae 89 +e+ e e +e e++L + ee +k+ + L++s e++e+ e++ ++ e+e+ ++q++++ ++L + + + + +++ +el ea FUN_001065-T2 434 KEKHETEMSEKEMKLSsqiKSNEELQKMVASLKDSLselESKEKVTERLLLLDAEKEQQfRDEKQAFHDSEKALHGQLQVSLDHNSKMSDELIEAR 529 688888888888888622235677777777777653111444444444444444444331344445555555566677777777777777777777 PP ERM_helical 90 eeiarleeekerkeeeaerlqeel 113 +ei+ e+e++ ++ +l+ ++ FUN_001065-T2 530 AEIEAKEKEVKDLNSKIGKLKLQA 553 777777777777777766666555 PP == domain 6 score: -8.9 bits; conditional E-value: 10 ERM_helical 12 eerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqe....aeeekerLeesaekeekekeqlerelaeaeeeiarleeekerke 103 +L+ + k+ +eL e++ +e e++ + + + +L+ ++++ +++eke+L ++ ++ e + ++e + +++i+++eeeke e FUN_001065-T2 508 HGQLQVSLDHNSKMSDELIEARAEIEAKEKEVKDLNSKIGKLKLQAKAkvtgLQNEKEKLSKEMQELEMHLLHEREEKLAIQKKISQIEEEKEGAE 603 555666666666777777777777777777777777665544433322111145555555444444444444446677788899999999999999 PP ERM_helical 104 eeaerlqeeleea 116 ++ ++l++ lee FUN_001065-T2 604 TKRTELEQALEEF 616 9999999988875 PP == domain 7 score: -2.5 bits; conditional E-value: 2.8 ERM_helical 37 eeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerela..eaeeeiarleee 98 + Lee+r +e+ ++ ++r ++ ++e+Lee e e++++++ ++e+ e e ++ + ee FUN_001065-T2 670 KILEEERYCMERRLDLITKERDSFKSKVEELEEMLEAEKEQQQKKAEEISsdEDAEHAKHMAEE 733 569******************************9999999999999998622445556666655 PP == domain 8 score: -7.5 bits; conditional E-value: 10 ERM_helical 8 kqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeae.rLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerk 102 ++ l++ + ++ee + + L+ ++ L+e++++a+ ++e +L + +++ +++ +e++ + + e ++e a++++ +++le+e e+k FUN_001065-T2 732 EESLMMHVEALQEENETLRVSLDLEKSALANLKEELKQAQLNQEnELHSEMDSLRQVLAEEKEKSGDLGSQLELSKQECAKKSQNVETLERELEQK 827 34678888999*****************************8775267777777777776666655555555577789******************* PP ERM_helical 103 eeeaerlqeeleea 116 + +e+l+ +l++ FUN_001065-T2 828 RSAVETLERQLQQS 841 *********99875 PP == domain 9 score: -4.2 bits; conditional E-value: 9.8 ERM_helical 14 rLkqyeeetkkaqeeLeesee.taeeLeekrreaeeeaerLeqkrqeaeeekerLee.....................saekeekekeqlerelae 87 L+q+ +e k++ +L + e +++e ++k++ +e+ ++Leqkr++ e+ ++L++ + +++ e l + e FUN_001065-T2 784 SLRQVLAEEKEKSGDLGSQLElSKQECAKKSQNVETLERELEQKRSAVETLERQLQQstqernkvledkdkeisnlqgALMENSSGFEVLNASFSE 879 566666666666666666665234566777777777777777777777777777777777777777777777777664445555555999999*** PP ERM_helical 88 aeeeiarleeekerkeeeaerlqeeleea 116 + ++ rl+e+ +ke+e+erlq+e+ e+ FUN_001065-T2 880 STIQLDRLQEQLAAKEAEVERLQKEMSEQ 908 ***********************999876 PP == domain 10 score: 5.8 bits; conditional E-value: 0.0073 ERM_helical 10 eleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerke 103 e++ L ee+ k +q ++++ ++L + e+ e ++L + e+e++ L+ + +++ + e+l + l e +++++ lee +++ke FUN_001065-T2 928 EMQLLLADKEETLKAVQTHTDKQTAELNSLRSRHDELSNEVQELRTVVDDKEAEIAHLKATTDEKDMSFEHLNTSLIESTSQLKDLEEIVQAKE 1021 788888999999999******************************************************************************* PP ERM_helical 104 eeaerlqeele 114 +e + ++ + FUN_001065-T2 1022 SELNSMRSNFD 1032 ***99987765 PP == domain 11 score: -2.7 bits; conditional E-value: 3.2 ERM_helical 33 eetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqe 111 + + L+e + e e L k +++e+ ++ L+ + e+++ + ++le a ++ e++ +e++ e++ e erl + FUN_001065-T2 1049 ATRLQGLQEALVAKEDEVTDLTSKLENQEASLKDLATRCEESMTKVRELEGNCASKDVELKAMESALEERGLENERLNK 1127 3444455555555555555666666666666666666666666666666666666666666666666666666666555 PP == domain 12 score: 18.3 bits; conditional E-value: 1e-06 ERM_helical 4 aerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarlee 97 er +e+ + L + ee+ + q++L+e+ t+e+L + + + L++ + e ++ Le + ++ ek+ +qle el ea+ i +++ FUN_001065-T2 1132 SERSVNEMNDSLAKKEEKYNALQANLNEKDATIEKLTSDCSHRDAKLDDLQKLLIAKDECVQTLENTLKEIEKSHQQLESELNEANGNIDGMKN 1225 588899**************************************************************************************** PP ERM_helical 98 ekerkeeeaerlqeel 113 + k+ee +l e++ FUN_001065-T2 1226 DIANKDEEIVTLTEKV 1241 **********999987 PP == domain 13 score: -1.2 bits; conditional E-value: 1.1 ERM_helical 41 ekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeelee 115 e + ++ e ++L k e+e++ L+ s e++ + +ql +la ++++++l+ ke++ l+ ++e+ FUN_001065-T2 1257 EASSQMRELHDLLTLK----ETELTVLRTSVENQGSSHQQLTSRLAGQSSQLQELTITLSNKEDQISSLERDVEA 1327 4444444444444444....5777889999999999999999999999999999999999999999999988876 PP == domain 14 score: 5.6 bits; conditional E-value: 0.0089 ERM_helical 24 kaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqee 112 k +e e+e +L + +e+ a +L + +ea + +++L+ +++e+e +l++ l+e+++ ++++ + +r e+e+ rlq FUN_001065-T2 1345 KLKETIAEKESENASLCSEVKELVFRASELNTRNEEANASLKALQDVFNEKENELFELKASLEEKTACLKQMDDSLQRTETEVLRLQSI 1433 556667788888889999********************************************************************975 PP == domain 15 score: 1.7 bits; conditional E-value: 0.14 ERM_helical 40 eekrreaeeeaerLeqkrqeaeeekerLee........saekeekek..eqlerelaeaeeeiarleeekerkeeeaerlqee 112 +ek+ +ee ++ +++ +++ e +erL+ +a+ ee++ eqle +lae ++ +++l e +k +e++ l + FUN_001065-T2 1435 DEKLADLEESRMGFAENSNQLNELRERLRNkeeesnllKANVEERNAivEQLESRLAEMSRNTTELHETLSAKNKEVDSLNMS 1517 55555555555555555555555555555533333333222222222335666666666666666666666666666555544 PP == domain 16 score: -5.4 bits; conditional E-value: 10 ERM_helical 10 eleerLkqyeeetkkaqeeLeeseetaeeLe....ekrreaeeeaerLeqkrqeaeeek...erLeesaekeekekeqlerelaeaeeeiarle 96 +l+e+L + eee++ + L+e +++ L+ + + ++e + +L+ k ++ ++k ++L++s e+ e e+ ++el+e+ +e + + FUN_001065-T2 1538 ALQEQLAEKEEEIQALESSLDERSQSISNLDtsltDTSTQLEDLRSQLASKDGKFAAMKkkaQALKKSYENAVSENENIQKELDELRKEREVFL 1631 699*********************99987761111566788888888888887766665111568889999999******************** PP ERM_helical 97 eekerkeeeaerlqeeleeare 118 eek++ e+ ++l e+ ++ + FUN_001065-T2 1632 EEKDAMEKCLTQLIEHKNQLQA 1653 *******999999988888775 PP == domain 17 score: 13.5 bits; conditional E-value: 3e-05 ERM_helical 18 yeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqe 111 +e + a e L+ s + +e L+ k e+++e +L+++ q++ +e+++L ++ +++e+ek+++e + e +e+++++e e+++ ++ + l++ FUN_001065-T2 1661 LEKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQTQRLIDERDELHSQLNQTEAEKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKK 1754 677778899**************************************************************************99999999999 PP ERM_helical 112 el 113 el FUN_001065-T2 1755 EL 1756 87 PP == domain 18 score: -2.0 bits; conditional E-value: 1.9 ERM_helical 23 kkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeeleea 116 ++ q+ L ese+ +++L++ e e++ + + +ea e L++ ++ +++ +l ++l ++ ++r +ee e+k ++ +lq e+ FUN_001065-T2 1817 EEIQAKLIESEKCSTKLKDDF---ELEKDDWKTRLEEAACENSSLKKGLSEMTEKQDSLTTQLNVSQKDLKRSQEELEMKNNQLSTLQAEVSHL 1907 567788888888888888754...555555555555555555666665555566679*********************************9887 PP ERM_helical 117 r 117 + FUN_001065-T2 1908 Q 1908 6 PP == domain 19 score: -0.6 bits; conditional E-value: 0.71 ERM_helical 16 kqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerl 109 +++ + k+ q+ L+++e +eL + e ++ + + +e+ e ++Lees k +e ++l++ l e +e++r+++ek++ e+ + l FUN_001065-T2 1936 LELQKQLKQQQHLLNDKEGEVTELNNLSLENKKALNFANTRIEELSERGNALEESFGKAVEETSNLQANLSEMASELRRVSQEKTELESDVFDL 2029 57899999999999999999999999998888888888899999999999******************************************** PP ERM_helical 110 qeeleearee 119 +++l+ a +e FUN_001065-T2 2030 KDKLRSADRE 2039 ****999876 PP == domain 20 score: -0.6 bits; conditional E-value: 0.73 ERM_helical 5 erekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleee 98 e + +l+++L++ e + +e+L + e ++ e+ +++e+++ Le +e++++ ++L + ek+++e + + + +e e+++++l +e FUN_001065-T2 2023 ESDVFDLKDKLRSADRELDAIKEDLTNASEGITTRNEQIKSLEKDRSHLESSLEEMQRKEQQLHKDLEKTNDELKYMDDLCKERESKLEELNKE 2116 55556799************************************************************************************99 PP ERM_helical 99 kerkeeeaerlqeeleear 117 +e+ e+ +e + + FUN_001065-T2 2117 REEDKERLSAAEEVFSKLQ 2135 9998888777776666555 PP == domain 21 score: 1.4 bits; conditional E-value: 0.17 ERM_helical 20 eetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqeel 113 ee +k +ee +e aee k++e+e L+q+++ +++e+e ++ ek +l l +a e+++ l++e+e+ +e e+l++el FUN_001065-T2 2111 EELNKEREEDKERLSAAEEVFSKLQEMESFYGALKQEKESLKTELEDVNNVLQEITTEKTNLDSNLVAAHERLNSLTNEREQVTAELENLKKEL 2204 56666677777778888888899999******************************************************************99 PP ERM_helical 114 ee 115 + FUN_001065-T2 2205 SD 2206 75 PP == domain 22 score: -4.5 bits; conditional E-value: 10 ERM_helical 10 eleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLee...saekeekekeqlerelaeaeeeiarleeeke 100 e +L ++ e + eL +++e+ + L+ + + + e e +q+ +e+e+e++ L++ + +++++e+ + ++l +ee++++++ +e FUN_001065-T2 2282 ETVTKLNEVTESKLVVDTELLDAKEKLNNLAVQHEWITSELENVKQEFSEQEKELANLKQkhlEENSSKEERDKSDERLLFRQEELKLMQSYSE 2375 6668999****************************************************9777889999****************999986555 PP ERM_helical 101 ...rkeeeaerlqeeleearee 119 k e + +ele+a+ e FUN_001065-T2 2376 dvvTKRIEELTIAKELEKAQVE 2397 1114555555566777777765 PP == domain 23 score: -11.6 bits; conditional E-value: 10 ERM_helical 37 eeLeekrreaeeeaerLeqkrqeaeeekerLee.....saekeekek...eqlerelaeaeeeiarleeekerkeeeaerlqeeleeare 118 + +ek + ++e +L++ +++ ++++e+L+ ++ek+++ + ql++ +ae+ee +++l+++ e + + +e+l l + r+ FUN_001065-T2 2442 NANKEKEETLQELHSQLANAEKDKKAALEELKLfldnsQKEKDQALQdleLQLAKAIAEKEEVVQELQSQLEIQSQTTEQLSAALDQLRD 2531 222333444444444444444444444444444555555555555555556899999999999999999999999999999999888876 PP == domain 24 score: -10.0 bits; conditional E-value: 10 ERM_helical 18 yeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqe...aeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaer 108 e+e k+++ +e+ + L+ + ++ e+e+ +++ + q +ee + + +++ + k++l++e a+++ e+a+l+ +k++++e+ FUN_001065-T2 2550 AENEGKQKELKWQEALSDLQNLKLEIEKREQEKVEMDTRLQTsvgQEEFDKSITDRNKLISNLKKRLKEERAAKKDELAKLQGSIAEKDANVEQ 2643 4444443333333333333333333333333333333322211113333344444555666666666666666666666666666666666666 PP ERM_helical 109 lq 110 l+ FUN_001065-T2 2644 LK 2645 65 PP == domain 25 score: 5.0 bits; conditional E-value: 0.014 ERM_helical 22 tkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarle 96 + +eeL e ++ ++ L+e + + ++e Le++ + ae+e+ L++ + kek++ler +++++e+++ e FUN_001065-T2 2645 KAMHEEELVEVHKNIKTLQEHNQTLKDKREALERDMSIAEDEMINLKRDLDEITKEKKDLERNHEQLKKELEEQE 2719 457899******************************************999999999999998888888776654 PP == domain 26 score: 8.2 bits; conditional E-value: 0.0013 ERM_helical 1 reeaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiar 94 re+a r+ +el+ +L + ee ++++e ++e +++L ++ +++ e+ + L++k q++ rLe + + +++ek ql+++l ++ee+ + FUN_001065-T2 2733 RENADRKTEELQLQLDALNEEVSEKKREEVNQQEEKQLLVDQVQQLSEAVQTLKNKDQDIV----RLENELQLSQEEKLQLAEQLTSLNEELVL 2822 9*******************************************************97665....6666666677899**************** PP ERM_helical 95 leeekerkeee 105 l+++ ++ ++ FUN_001065-T2 2823 LKDAYDQLQAA 2833 *9998775544 PP == domain 27 score: -5.3 bits; conditional E-value: 10 ERM_helical 15 LkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeek 99 L++ e k+ q+eL +++ e+L+ k r+ ++ + ++ ++ e + e ++++ ek +le+ + e+ ee+ ++++ek FUN_001065-T2 2907 LHKTRMELKEIQAELTKAKALNEKLKAKVRVFMKKERAKSESVRDVESSDMKAEIDKARQ--EKINLEKTALELREELVEIVREK 2989 666777999999******************998888888888888888888888888877..99999999999999998888887 PP == domain 28 score: -2.7 bits; conditional E-value: 3.2 ERM_helical 17 qyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerke 103 +++e++ka++e e+ta eL e++ e+ +e++ ++++++++L +++++e e+ e+ lae +eei+r+ +++ ++ FUN_001065-T2 2956 DMKAEIDKARQEKINLEKTALELREELVEIVREKDGTI---GDLKQKIRQLLNEKSRNEVLVEKYEKLLAERDEEIKRIGANADVEA 3039 58999**********************99999998764...568999*******************************986655444 PP == domain 29 score: 11.8 bits; conditional E-value: 0.00011 ERM_helical 3 eaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarle 96 e e+ k+ +e+ L ee+ ++eL +eeL+ ++r+ +e ++L + + ++ + + L+ ++ +ek + ++e+ +++r++ FUN_001065-T2 3070 ELENTKDGYEKVLSDKDEEIGNFKRELVSCNIETEELKGRLRQTQESFDELNKLKVDFDHIISGLRGDLQQALEEKAVADQLAHEFRVQLERMK 3163 67999***********************************************************************999999999999998887 PP ERM_helical 97 e 97 + FUN_001065-T2 3164 S 3164 5 PP == domain 30 score: -11.6 bits; conditional E-value: 10 ERM_helical 26 qeeLeeseetaeeLeekrreaeeeaerLeq.krqeaeeekerLeesaekeekekeqlerelaeaeeei 92 q+eL+++ + ++L+e +++ + + + +++ e +++Le + + ++ +q+++ e++ + FUN_001065-T2 3261 QNELKQASDLNNKLKEALKKKRSKPRSKSSgEHEMSNETIAELEVIRAAKVESDKQMAHLRLELDNFV 3328 55555555555555555555444433333202222233334444422222222222222222222222 PP == domain 31 score: -11.5 bits; conditional E-value: 10 ERM_helical 25 aqeeLeeseetaeeLeekr.reaeeeaerLeqkrqeaeeekerLee........saekeekekeqlerelaeaeeeiarleeekerkeeeaerl 109 ++eLe + ++L +++ ++ e +++Le ++++ +e+e+++e +++++++ +l++ e++ ++ +++++++ e e FUN_001065-T2 3407 ENAELENDLRYNKSLVKEStDRVSELKRELESREEKHLKEIEEIKErhdqvliaKQKETDEAILELRQINTELQDNLQSVSDNRDATERELIGT 3500 5677777777777776665146777788888888888888888888777776644444444457777777888888888888888888887777 PP ERM_helical 110 qeeleea 116 + +le++ FUN_001065-T2 3501 RAKLEQV 3507 7777665 PP == domain 32 score: -9.9 bits; conditional E-value: 10 ERM_helical 4 aerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek.eqlerelaeaeeeiarle 96 +e + q+++e L q+ee a + + e++ L+e+ +e+e + +L+ + +e ++e+++ + + +++ +ek +l++e + +++++++le FUN_001065-T2 3515 IEEKSQKIQELLSQMEENRINADNVIVQLERSESTLQEQVQELELSRTELKTQLEETRAEMRKQRLRFQRSVEEKeTELREEKEGLQQQMQQLE 3608 6889999999********99999999999999999**************998877777776666666666666662358888888888888887 PP ERM_helical 97 e 97 FUN_001065-T2 3609 A 3609 5 PP == domain 33 score: 6.1 bits; conditional E-value: 0.0061 ERM_helical 3 eaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarle 96 ++++ +++ ee L q ++ + k +eeL + + ek++ a+ e++ e+ r+++ + + L+ ++ + + + e+ ++e++ ++++++ FUN_001065-T2 3603 QMQQLEAKFEELLSQSQASISKLEEELAHTNMELVSFNEKLQTADGEKQDIEKLRNNFDHIISGLRGDLQQAINARAAAEELAHEFQVQLEKMR 3696 566667788999********************************************************************************** PP ERM_helical 97 eekerkeeeaer 108 + + ++e+++ FUN_001065-T2 3697 KSNPTTANEVDE 3708 999999998876 PP == domain 34 score: -2.2 bits; conditional E-value: 2.3 ERM_helical 67 Leesaekeekekeqlerelaeaeeeiar 94 Le ++ +e++ + +le+ l e ++ +r FUN_001065-T2 3721 LEATQREEANLRAALEATLIERDALQNR 3748 2222333333333333333333332222 PP == domain 35 score: -4.2 bits; conditional E-value: 9.5 ERM_helical 19 eeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerlqee 112 e e++ ++eL++ ++ e+L+ k+r + ++++ + e +++L+ + ek +ek + e+ +e+ e+ ++++eke +e +r +e FUN_001065-T2 3805 EVEIENLKNELQRVKNVNEKLKAKLRTMMKKRRVKSDSGDEDSSVRNELQTELEKIRQEKLEREKTCQELRLELDTFVREKESITNELKRRIDE 3898 6689999**********************99999999999999999999999999999999999999999999999998888887777765555 PP ERM_helical 113 l 113 l FUN_001065-T2 3899 L 3899 4 PP == domain 36 score: -10.4 bits; conditional E-value: 10 ERM_helical 11 leerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeeker 101 l++r+ ++ ++ +k + e+ e ++ + ++ e+ + + e++ +a + +e L++++++ +eke+l + +e e+ ++l+ e FUN_001065-T2 3892 LKRRIDELSAKNEKSNTLIEDLEAQVKQKDGQLLELMMDVRVVENDNDQAWQNVETLRHENADLLAEKEDLISQSKEHEKDSSELKVYYES 3982 5555555555555555555555555555555555555555555555555555555555555555555555555555555554444433333 PP == domain 37 score: 3.2 bits; conditional E-value: 0.047 ERM_helical 13 erLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeea 106 ++L ++ e+ k ++ ++++e + +++ a+ Le++r a +e+e+L+++ ++ ++e+e+ + ++++ ++ l+e+ +r e FUN_001065-T2 4003 NQLDEVTEKYKTELRATRDQHEGI------ILQIQSHADNLEKERLLASKETEQLKSQLKDFKNEREDIGKLKHNFDHIVSNLREDLQRALEGK 4090 444444444444444444444433......3478888999999999999999999998888888888888888888888888888777655444 PP ERM_helical 107 er 108 FUN_001065-T2 4091 AA 4092 44 PP == domain 38 score: 5.3 bits; conditional E-value: 0.01 ERM_helical 3 eaerekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLe 54 ++e +++elee+L ++ e+ ++++L+ +e +++Le + +e+e + e FUN_001065-T2 4127 DIETREEELEEKLDAVQTEAANMRKALDFYKEDKQRLENEVANLERELHERE 4178 699************************************9888888765544 PP == domain 39 score: -8.7 bits; conditional E-value: 10 ERM_helical 16 kqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleeekerkeeeaerl 109 +++ ++ k+q+eL++ + e+L+ k++ + ++++ + + +e ee +e+L + +k +ek + er ++++ + ++++eker+ e ++ FUN_001065-T2 4235 QKVRDDWYKMQNELDKVKAVNERLKTKLKTLMRKRKGGKVETSE-EENREELHTELAKVRQEKLETERAAQQLRIDLDEIVREKERRVVEHKTR 4327 67788888999999999999999999999999888876666544.7777888777777765555555555555555666777777766555544 PP ERM_helical 110 qeel 113 +++ FUN_001065-T2 4328 MQQV 4331 4444 PP == domain 40 score: -1.8 bits; conditional E-value: 1.7 ERM_helical 11 leerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek....eqlerelaeaeee 91 l e+++++ ++ ++++ L ++ + L +++++ ++ + e++ +a e+erL e +ek ++le+el +++e FUN_001065-T2 4359 LVEQIQSLGDKLHEVEQSLAQAMSENRNLNTVLEQLQLQKVKAERELHAATGELERLLEGDRPILAEKeqriSNLEAELSDLKES 4443 6677888888888888888888888888888888888888888888888888888888866555555511234566666655554 PP == domain 41 score: 12.1 bits; conditional E-value: 8.5e-05 ERM_helical 6 rekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLee...............saekeekekeqlere 84 ek++le r k +e+ ++ ++ + L e + a e ++ e+ ++e++++ +r+e+ + +e + ++ e+e FUN_001065-T2 4478 TEKKQLESRVKAFEDGIEDINKLRTNFDHIISGLREDLHGALEGKAAAEEIANELQMKFRRFEKssvsselkvedvcigTEDMESRVLSDNEAE 4571 79*******************999999999***********************************************777777777779999** PP ERM_helical 85 laeaeeeiarleeekerkeeeaerlqe 111 +++++ +a+++eek ee++ l + FUN_001065-T2 4572 IEDLQTAVAQFREEKYDLEEQVLALDK 4598 **************9999998877765 PP == domain 42 score: -1.9 bits; conditional E-value: 1.8 ERM_helical 37 eeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekekeqlerela 86 L ek +++++ e e+ ++e + +e+L + +k ke+ + ++e++ FUN_001065-T2 4605 GDLMEKQEQIQTLEEDIERLAAEHATSMEQLVLEVNKAGKERDEIRKEMQ 4654 46778888888888888888888889999999999999999988888875 PP == domain 43 score: 0.1 bits; conditional E-value: 0.44 ERM_helical 52 rLeqkrqeaeeekerLeesaekeekekeqlerelaeaeeeiarleee 98 q +e+ ++ke+ +e+++k+ eqle el e+ + i++l++e FUN_001065-T2 4660 AVMQSNKELDQMKEQYTLLKENSAKKMEQLEGELSEKRQVIEKLSDE 4706 4567889************************************9987 PP == domain 44 score: -10.9 bits; conditional E-value: 10 ERM_helical 6 rekqeleerLkqyeeetkkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLeesaekeekek......eqlerelaeaeeeia 93 +e ++l ++Lk+ +++ a Le ++ + + Le++ + + ++ + e ++ e +++L+e+ + + ++ + +e+ e++ ei+ FUN_001065-T2 4750 KETENLRMKLKKDYDQM-LASLKLEVEQSRQQNLEKE-KFIHNQRIEVESLVRDKESLITKLRETGQVTRETLqrtdgdAADDDEIVELKNEIS 4841 56666666666655555.4555666666666666543.66677777777777777777777777444333332112222334567777777777 PP ERM_helical 94 rleeekerkeeeaerlqeele 114 +l++e + + e ++l ++ + FUN_001065-T2 4842 LLRKECQDCRVEKDKLYDKFH 4862 777777766666666666555 PP == domain 45 score: -4.7 bits; conditional E-value: 10 ERM_helical 8 kqeleerLkqyeeet.kkaqeeLeeseetaeeLeekrreaeeeaerLeqkrqeaeeekerLee.......saekeekekeqlerelaeaeeeia 93 k++l ++++ e k+ ++ L+e+ + a++ ee +++ e ++ L +k++++ ++k ++e+ e +eke l+++l+e +++ FUN_001065-T2 4854 KDKLYDKFHDAVESLrKELERSLHEKDNLAQKTEETLKQNRELQQSLLEKQSALTKAKVQFEHigkgwrnDLEAARAEKELLQKQLEERTSQSV 4947 6666666666555541456888888889999999999999999999999999999999999999999988666666788888888888777655 PP ERM_helical 94 rle..eekerkeeeaerlqeelee 115 ++ e+e+ + e+l+ +l+e FUN_001065-T2 4948 TIDiaPEEEESWQTIEELRLRLHE 4971 544003333333455555555555 PP >> TSCPD TSCPD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.1 0.00041 1 15 76 .. 1717 1777 .. 1699 1794 .. 0.82 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00041 TSCPD 15 vtkgcsgkiyvtvneddgkifeVfftggcsgnllealsrlvSlaLregvpveeiieqLkgir 76 + +++++++vne ++k +V+f ++ l+ l + + l Lre ++ e+i++Lkg++ FUN_001065-T2 1717 TEA-EKKNMEMSVNEGNEKMSQVEFERNEVQSGLDHLKKELDLKLREATDLREVIDHLKGVN 1777 333.489******999**********66666669*************************985 PP >> PRF Plethodontid receptivity factor PRF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.5 0.00022 0.56 90 160 .. 3565 3635 .. 3551 3643 .. 0.82 2 ? -3.1 0.5 2.5 6.4e+03 94 157 .. 4644 4710 .. 4635 4714 .. 0.82 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00022 PRF 90 dtfikqtdetrlknnlyfysaiveflkeamteqedlnpaelalkakfeeamansntliskisdimtqmgms 160 t +++t k+ l f ++ e e e+e l+ l akfee +++s++ isk+ + ++ m FUN_001065-T2 3565 KTQLEETRAEMRKQRLRFQRSVEEKETELREEKEGLQQQMQQLEAKFEELLSQSQASISKLEEELAHTNME 3635 45555555555678999****999999**********************************9988776665 PP == domain 2 score: -3.1 bits; conditional E-value: 2.5 PRF 94 kqtdetrlknnlyfysaiveflke..amteqedlnpaelalka.kfeeamansntliskisdimtqm 157 k+ de r + ++ + +a+++ ke m eq l + a k ++e +++ +i k+sd + q+ FUN_001065-T2 4644 KERDEIRKEMQINMDAAVMQSNKEldQMKEQYTLLKENSAKKMeQLEGELSEKRQVIEKLSDEIGQF 4710 678999999999999999999998446999999988888877526888999999*******988775 PP >> Astro_p19 Astrovirus p19 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.6 0.045 1.1e+02 106 143 .. 1662 1699 .. 1635 1708 .. 0.82 2 ? 3.2 0.6 0.029 73 111 145 .. 2794 2828 .. 2776 2850 .. 0.86 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.045 Astro_p19 106 ihkanalqerlrlsqeekatlaldvqflqhenvrlkem 143 +k +e l++s +ek tla v lq+e lke FUN_001065-T2 1662 EKKLGVADESLQISSNEKETLAAKVIELQQELGLLKEQ 1699 456677899**********************9999986 PP == domain 2 score: 3.2 bits; conditional E-value: 0.029 Astro_p19 111 alqerlrlsqeekatlaldvqflqhenvrlkemip 145 l++ l+lsqeek la ++ l+ e v lk+ FUN_001065-T2 2794 RLENELQLSQEEKLQLAEQLTSLNEELVLLKDAYD 2828 57889*************************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (5064 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5247 (0.205402); expected 510.9 (0.02) Passed bias filter: 931 (0.0364455); expected 510.9 (0.02) Passed Vit filter: 472 (0.0184772); expected 25.5 (0.001) Passed Fwd filter: 160 (0.00626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 8.80u 0.42s 00:00:09.22 Elapsed: 00:00:01.22 # Mc/sec: 16846.21 // Query: FUN_001066-T1 [L=841] Description: FUN_001066 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-32 110.4 0.0 3e-31 108.7 0.0 2.0 1 Transglut_N Transglutaminase family 2.1e-14 54.0 1.1 2.2e-08 34.6 0.1 2.5 2 Transglut_C Transglutaminase family, C-terminal ig like d 2.7e-12 47.4 0.1 6.5e-12 46.2 0.1 1.6 1 Transglut_core Transglutaminase-like superfamily ------ inclusion threshold ------ 0.14 12.6 23.6 0.27 11.7 23.6 1.4 1 Trypan_PARP Procyclic acidic repetitive protein (PARP) 0.17 12.5 3.2 15 6.3 0.1 3.3 4 Cep192_D4 Cep192 domain 4 1 10.1 3.5 30 5.4 2.4 3.4 3 Big_12 Bacterial Ig-like domain Domain annotation for each model (and alignments): >> Transglut_N Transglutaminase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 108.7 0.0 7e-35 3e-31 2 114 .] 156 268 .. 155 268 .. 0.98 Alignments for each domain: == domain 1 score: 108.7 bits; conditional E-value: 7e-35 Transglut_N 2 svdlqkeeNnkeHhTdeysskelvvRRGqpFkitlkfnrpfdpskdklslevetgpkpseskgtkavfplseeedeskWsakveesegnsltlsvt 97 +dl ++eN+k+H+Td+y+ ++l++RRGq F++t++fnr+++p+ d + +++ tg++p eskg+ +++++e+ ++ +W ++++e++gn+++ls++ FUN_001066-T1 156 AIDLFISENRKAHRTDDYDFQQLIIRRGQVFDVTVTFNRDYRPADDVILVQLATGKRPLESKGSLKRVTVQESLTPMTWGMQIKENDGNTVRLSIM 251 589*********************************************************************************9999******** PP Transglut_N 98 spanapiGrYklsvevs 114 ++a+a+iG+Y++sve++ FUN_001066-T1 252 PAATAIIGQYEMSVETK 268 **************985 PP >> Transglut_C Transglutaminase family, C-terminal ig like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.6 0.1 5.3e-12 2.2e-08 1 79 [. 626 703 .. 626 731 .. 0.85 2 ! 17.8 0.1 8.9e-07 0.0038 9 102 .. 748 836 .. 739 838 .. 0.90 Alignments for each domain: == domain 1 score: 34.6 bits; conditional E-value: 5.3e-12 Transglut_C 1 pelkievlesavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvrlkilpsky 79 +++++++ ++ g++l++sv+++ +++e+ +++ +nl+a +y+Gv+a+ k+k+l++ L eek+v+l+i p y FUN_001066-T1 626 IHFDLKLEDTVYAGNSLDASVVVQSESEET-REILVNLTAMLNFYTGVSAKRLKSKKLKFVLNSREEKRVPLTIEPDDY 703 699***************************.*******************************************99999 PP == domain 2 score: 17.8 bits; conditional E-value: 8.9e-07 Transglut_C 9 esavvgqdltvsvllkNplseelkdvklnlcaftveynGvlaaefkkksleltLePkeeksvr.lkilpskyGprkllvelssdalakvkglkev 102 +++ v d+tv+++++Npls +l+ + f +e + + + + + +l + ++++ee+ ++ +k++ + +G++ +++s+ l++++g+ +v FUN_001066-T1 748 SQLSVDEDVTVTATFTNPLSIALTS-----GQFHLEATRM-KPKTMVVDLMGPVGANEEVAMDaVKFTSTMTGTHHVAISFQSNELTDIHGECTV 836 5678999****************99.....88999****9.68999999**********999648*************************98665 PP >> Transglut_core Transglutaminase-like superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 0.1 1.5e-15 6.5e-12 46 107 .. 410 503 .. 394 504 .. 0.87 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 1.5e-15 Transglut_core 46 vletkk....GncedfaslfvallRalGipaRlvtgylagede.....................vrsedaHawaevyl.......dgggWvpvD 107 + etk+ G+c+ f+ l+++l+RalGip+R vt++ +++d+ + +++H+w+e ++ +gW++ D FUN_001066-T1 410 FWETKQtvkyGQCWVFSGLVTTLMRALGIPTRSVTNFDSAHDTdasmtidlhfdeegdvidgmnDSVWNYHVWNESWFkrpdlpdGHDGWQAHD 503 4444444455******************************999********************999************9998876667798877 PP >> Trypan_PARP Procyclic acidic repetitive protein (PARP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 23.6 6.4e-05 0.27 52 111 .. 30 89 .. 19 98 .. 0.76 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 6.4e-05 Trypan_PARP 52 ddtngtdpepepepepepepepepepepetepeeepepepepepepepepepepepepep 111 +d t e ep+p+ +p+p pe +p+p+++p++e + +p+p+p e +p ep+p+p p FUN_001066-T1 30 QDGPVTSDESEPQPQSQPQPHPEMQPQPQPQPHPELPLQPQPQPHREMQPVIEPKPQPHP 89 455556667777777777888888888888888888888888888888888888888887 PP >> Cep192_D4 Cep192 domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 2.7 1.2e+04 62 79 .. 176 193 .. 148 194 .. 0.71 2 ? 5.6 0.0 0.0056 24 16 83 .. 636 703 .. 634 710 .. 0.81 3 ? 6.3 0.1 0.0034 15 31 110 .. 709 793 .. 703 796 .. 0.78 4 ? -2.2 0.0 1.5 6.3e+03 76 95 .. 806 825 .. 799 836 .. 0.76 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 2.7 Cep192_D4 62 reltlkpkeertvsvlFa 79 ++l++++++ v+v+F+ FUN_001066-T1 176 QQLIIRRGQVFDVTVTFN 193 568999999999999995 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0056 Cep192_D4 16 vklgkskqqkltlrntsskklklrlsirgsdqcFklfgeeerltssreltlkpkeertvsvlFaPtsv 83 v g+s +++++++s+++ ++ ++++ + ++ ++ ++ +++ +++l+++ee+ v ++ +P FUN_001066-T1 636 VYAGNSLDASVVVQSESEETREILVNLTAMLNFYTGVSAKRLKSKKLKFVLNSREEKRVPLTIEPDDY 703 6678999999*******************9996664444444566888***********999999865 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0034 Cep192_D4 31 ts.skklklrlsirgsdqcFk.....lfgeeerltssreltlkpkeertvsvlFa.PtsvgaasgkLeikslessqsgikftIpLsG 110 + s k ++ +++++dq+F+ +++ e ++ + +l e+ tv+ +F+ P s++ sg+ +++ + + ++ ++ L G FUN_001066-T1 709 ACdSIKFYVKGKVTETDQSFSkqkdvEVEKPELQVTASVSQLSVDEDVTVTATFTnPLSIALTSGQFHLEAT--RMKPKTMVVDLMG 793 444777788889999999**99998655555557778889**************6488*********99999..4455556777776 PP == domain 4 score: -2.2 bits; conditional E-value: 1.5 Cep192_D4 76 vlFaPtsvgaasgkLeiksl 95 v F+ t +g+++ +++++s+ FUN_001066-T1 806 VKFTSTMTGTHHVAISFQSN 825 77888888888888888776 PP >> Big_12 Bacterial Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 2.7 1.1e+04 17 29 .. 181 193 .. 176 197 .. 0.81 2 ? -0.5 0.0 0.48 2.1e+03 5 31 .. 439 465 .. 436 472 .. 0.90 3 ? 5.4 2.4 0.0071 30 4 31 .. 738 765 .. 735 840 .. 0.85 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 2.7 Big_12 17 kagetatvtitfs 29 + g++++vt+tf+ FUN_001066-T1 181 RRGQVFDVTVTFN 193 5688999****98 PP == domain 2 score: -0.5 bits; conditional E-value: 0.48 Big_12 5 PtvtisvadsalkagetatvtitfsEa 31 Pt +++ dsa ++ ++t+++ f E+ FUN_001066-T1 439 PTRSVTNFDSAHDTDASMTIDLHFDEE 465 999999999***************997 PP == domain 3 score: 5.4 bits; conditional E-value: 0.0071 Big_12 4 aPtvtisvadsalkagetatvtitfsEa 31 +P++ ++ + s+l+++e tvt tf++ FUN_001066-T1 738 KPELQVTASVSQLSVDEDVTVTATFTNP 765 6888888888888888888888888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (841 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1116 (0.0436876); expected 510.9 (0.02) Passed bias filter: 726 (0.0284204); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.41u 0.47s 00:00:00.87 Elapsed: 00:00:00.47 # Mc/sec: 7219.47 // Query: FUN_001067-T1 [L=814] Description: FUN_001067 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-36 122.3 0.4 1.5e-17 63.6 0.0 2.6 2 WHD_E2F_TDP E2F/DP family winged-helix DNA-binding domain ------ inclusion threshold ------ 0.015 15.6 0.1 0.043 14.1 0.1 1.7 1 TrmB Sugar-specific transcriptional regulator TrmB Domain annotation for each model (and alignments): >> WHD_E2F_TDP E2F/DP family winged-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.5 0.1 1.9e-19 2.5e-15 11 65 .] 17 75 .. 13 75 .. 0.84 2 ! 63.6 0.0 1.1e-21 1.5e-17 1 65 [] 186 269 .. 186 269 .. 0.97 Alignments for each domain: == domain 1 score: 56.5 bits; conditional E-value: 1.9e-19 WHD_E2F_TDP 11 kflellkesekgv....idlneaaeeLgvkkRRiYDilNVLeglglieKksknkikWig 65 +fl+++ e +k i l+++a+ L v++RRiYDi+NVLe++++i++ +kn++ W+g FUN_001067-T1 17 RFLSKYPEYPKVNefieIGLDDVARDLSVERRRIYDIVNVLESVEVISRYAKNRYVWHG 75 7777887733333344599**************************************98 PP == domain 2 score: 63.6 bits; conditional E-value: 1.1e-21 WHD_E2F_TDP 1 kekSLglltkkflellkesekgvidlneaaeeLg...........vkkRRiYDilNVLeglglieKks........knkikWig 65 k+kSLg+l++kfl+l+ +e g ++l++aa+ L +k RR+YDi+N+L++l+lieK++ k+ ++Wig FUN_001067-T1 186 KDKSLGVLSQKFLMLFLVAETGYVTLEDAANVLIgeeeegqtkykTKVRRLYDIANILSSLQLIEKVHihsiqtgrKPGFRWIG 269 79**************999*************************************************9999999999999997 PP >> TrmB Sugar-specific transcriptional regulator TrmB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.1 3.4e-06 0.043 26 61 .. 37 72 .. 33 77 .. 0.89 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 3.4e-06 TrmB 26 deiaeesgvprskvYevLrsLedkGlVerekgrpkl 61 d++a+++ v+r ++Y++++ Le+ ++ r +++++ FUN_001067-T1 37 DDVARDLSVERRRIYDIVNVLESVEVISRYAKNRYV 72 89***********************99998877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (814 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1356 (0.0530828); expected 510.9 (0.02) Passed bias filter: 668 (0.0261499); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7734.59 // Query: FUN_001068-T1 [L=2070] Description: FUN_001068 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0 1050.1 0.1 0 1049.6 0.1 1.2 1 Nup192 Nuclear pore complex scaffold, nucleoporins 186/192 Domain annotation for each model (and alignments): >> Nup192 Nuclear pore complex scaffold, nucleoporins 186/192/205 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 1049.6 0.1 0 0 1 1664 [. 9 1710 .. 9 1711 .. 0.92 Alignments for each domain: == domain 1 score: 1049.6 bits; conditional E-value: 0 Nup192 1 WsleafkeLynsieaasss..penldelelllkklkqdLknllknppkneksRsqLkkek.gkitlsdgd.eyklnqefiqealiLsdeLdLdE 90 W + +keL++++e++ + pe+++ele++lkk+k+dL++llknppkn R++Lk + ++++l+ + +++l ++f+qe+liLsd LdL+E FUN_001068-T1 9 WRP--YKELQATVERSLFKkrPEVYHELEVALKKFKPDLTSLLKNPPKNVDHRDKLKRAPtSGLQLTAHAeKQNLPEQFVQEVLILSDVLDLNE 100 777..*********876554345*********************************98779*******999*********************** PP Nup192 91 lvaaellltaqeqsaekpglsllevAvllyydrrkyilqilryllqvkseeeedeekllaswsakklvtnilksleeiekllsklkdlvdkaki 184 +v+ +lll++++q+++ pgl++++vAvlly+d+r++++++l++l+q s e ++++ l+ + ++l+t+++++l + +l+ ++ +++++ ++ FUN_001068-T1 101 FVCTDLLLAGEQQQPNFPGLTRGLVAVLLYHDGRRCLVSALKTLIQ--SREGITWTMGLN-EDLSQLATKFTDELLQE-GLITTIIEQLQELDV 190 **********************************************..444444555444.4599***********99.*************** PP Nup192 185 lgei...qdnrfletikfkr...dsLlkehelLaqilfglvkqrglekedikkllkha......kkl.dknDvlilhylpallaafssleelss 265 +e+ ++ + +++ ++k+ d+++++++lLa++l+ + q l+k ++++ll+ + + + ++ D ++l++l+a+l+++ ++ + FUN_001068-T1 191 QKELdklERGQGIGDEHHKQqliDFITDQRQLLAECLYCFACQAPLPKREALQLLSALkkrpsiD-AdGTLDSVTLTLLMAMLYCL----NVDP 279 **998889999999999999*************************************65888754.45999***************....8899 PP Nup192 266 lkdvrelhekitkslesewplls....................kglkaaikfvflaefiswckkepeertkkfdfkedieklieeaiedgafef 339 l+++ e++++i +++ +plls +g+ +i+f++ + + s+ +++p + + ++d+ e++e +++ a++ +f f FUN_001068-T1 280 LDEAAEIQSSIREET---FPLLSdhrfipefhleiseqeswqnQGMCSCIQFAWALALRSC-SHWP-NLVGAVDVLEEDECVLDLAVDGCVFGF 368 ***********9999...99999*************************************9.***9.779************************ PP Nup192 340 llsiaaetsakewedelrydfrslLqrkiprlspkklllseefeefllrqlhefiqdfIsnmadvLtkLrdeEedsllsqeslqqeg..ppenl 431 l ++++ s ++ee+++++lh++++ fI +m+ ++++Lr++ +++++ +++ q+g pp l FUN_001068-T1 369 LRNCVVRAS------------------------------TFHQEEYFVQRLHSLVTGFIVKMPLKVKELRNQGDEAARIIQAHLQDGvePPVGL 432 *********..............................99*********************************************98444433 PP Nup192 432 ddieqkadLErFllivaylYesrp...elaaeFW..........................sdkesnlygFiewAssrltsplisafceMLssLs 496 ++E+F+ ++ lYe++p elaa+FW s k+++l +F+++A+++l++pl+++++ ML +L+ FUN_001068-T1 433 -----SKHFEDFMKMIGDLYEKDPcglELAADFWcptdtglgtsfspystgissalrqraSQKQVSLNKFLRLAGDLLPPPLFVPYLDMLTGLA 521 .....469***************************************************9999******************************* PP Nup192 497 sgeenaaaafefLkdenksgkkkrsssvswdqifksLsyYidkl.qepe.sdlkqrqkkqeaeetdyrsraleeeleeesiiflssylrLissv 588 +++e+a+++f++Lk++ + g vswd++f sL++Y+ +l q+ + +++ + +++ +r + ++++e++++l+++lr+ ++v FUN_001068-T1 522 NSPEAAHHCFNLLKSSAN-GP------VSWDHFFGSLKQYYMDLrQD-SgRSVMMYGSLIRETSLSHRPDMSNYNITPEELEGLEAVLRVTERV 607 **************9887.55......*****************555.344443333333346777888888999******************* PP Nup192 589 aknseearkellesasnrfldiLlgllsckvptpLkgailktLsaLvkkseeereeiWrsLDrwifkglqllstvp.ktsslkqssslsekeaf 681 a+++e+ar +++es+ + ++ L+gll c+vp++Lk++il+tL+a++k s+e ++++W++L+ ++q+l+tv+ + +++++ +++ e +++ FUN_001068-T1 608 ADKDEIARLAMCESQAWLPIASLFGLLGCSVPVKLKAQILTTLAAFAK-SPEIASSMWFTLE-----QSQILQTVTpTGQAVQPGGIQVELNEL 695 ************************************************.*************.....*******8868888888********** PP Nup192 682 esileeysevraflqLlkaLlkpledssslkgklpfPekLGagyRkpGiepYldfvldevflk.snrdlkdpaekwelqlsclelletsLksfd 774 e + e+y+e+rafl+Ll++L+ ++p+P++LG+gyR pG+epYl f+ d+vflk s+r +++p+ekw +++ +l+++ ++L+ + FUN_001068-T1 696 EARDETYPETRAFLKLLNNLT-----------DIPLPSALGSGYRVPGFEPYLTFLRDDVFLKfSSRGYQNPNEKWIVASDVLQIFFKLLDGYT 778 *********************...........9************************************************************* PP Nup192 775 eslilnsapsginldslvstsdlatyvklhpfaavlnllfnekvlkaLlkiisegvdelds.l..aegkseleelvlraLeilekvLelqetyl 865 ++ +++ + ++ +++d + k+++ +++++l++ l++Ll++i+ ++++ld + +egk+ele+ l++L+++e +Le+qe+++ FUN_001068-T1 779 PKPEDFVDQFVE-----LQGGDRIVVPKPPGLNLMVHMLNDTPTLRMLLSVIDGASTSLDHlTfnSEGKNELEKAALLCLRMIETALEKQEQFA 867 *********999.....5789****************************************5489999************************** PP Nup192 866 eellpilkkskniyipknvgnaglssfedallfnLslvv......nlglYvgldn..peialaslkiLeklssspkvskssaeasrllkknkll 951 + l+ + + ++ + +s ed ll+ ++ ++++Y + ++++l+ +kiL + +s +v + +l+ FUN_001068-T1 868 NTLRSVT-Q------QSAIM---VSRLEDLLLSINPRTSaadyllKIMRYLCHLHtgADLSLSVMKILCFVCQSTQV------------QRHLI 939 ***8887.2......22222...5667777776555555666666*****9999999*****************999............899** PP Nup192 952 tvfesvde.serIkqgfieqleaeieeeeseeeeee.................lkiKleILdfLnsnLsasskeptvahfLLGfdvrndlslge 1027 ++ +++ s++I gf+++le e+ +e + e +++ +IL ++ ++L+ p++ahfLLG+++r+ + +++ FUN_001068-T1 940 SICMTNQSlSKKILIGFVDHLEINEPEDLHERD--ElgkdfvdetahsvsqirNAVRQNILRLILHSLQLP--PPNLAHFLLGYELRKPVAKTN 1029 999999888*************66544444444..3459*****************************985..8******************** PP Nup192 1028 eqqsgliasessllhsllslLesslelisegdkidyaparLaskileillkLcsnpltseltLryLren..ellrhllslepkidkntlWngqe 1119 q++g+ ++++lh++l+lL++ +++ +g + + ++++a++++++++ Lc+n+ t+++tLryLr++ +l++hl +l++k + FUN_001068-T1 1030 LQDPGVQGASKTCLHAVLDLLNKGVDTH-HGPSCVTETPKFAELAYQLIYSLCANKDTATPTLRYLRTShdFLYQHLQHLPFKKLVSIG----- 1117 *********************8888888.4455999********************************9**************555555..... PP Nup192 1120 fdgdlssnkefissesagallsFlkyrslllqylslelhslsqsgspskkkrivdlLlgnntl............................... 1182 + + ++ + + +++s+ll+++++el++++q +++s+++r++ lL+g+ + FUN_001068-T1 1118 --S-----DG---EQPTLPMQTIASQQSWLLKTAAIELRMTAQGRQRSHAQRLLGLLMGEHSAlrpnvgtsqfqemvprrleddftsadtsqaa 1201 ..2.....22...456667777889**********************************99446**********************99988887 PP Nup192 1183 ..e.eeengspkildlldflnfefknseeqpqlefld..nlsldLdkcekkdedegnklydisklekllkleksslkslaqkeekaeiekeiea 1271 + ++++ ++k+l +l +++f ++ + ql+++d + + +ce+k ed + +++ +l+kll+ e + +q++++a++++ + + FUN_001068-T1 1202 yaDmGQSQTRRKLLAILESVDFT-QDVPPALQLNYFDagVTEEAIASCEQKAEDIDVMFCNVPVLHKLLMTE---IT-GVQGTATAGQRNFLIQ 1290 7744557789*************.99999**********99*************9999**************...66.799************* PP Nup192 1272 EiekilefltklnrqkelkaaqlkvLhsWvqLvqvlvs...dgelestersnfilevlqailpkindyveediafaeeLaslasvllfdlyekd 1362 E+++il++++ n+++e + + +++W+ +++v ++ ++ ++ ++r+++i e+lq++l +i d + + eL+s +s++++ l++++ FUN_001068-T1 1291 EVRDILQNVVLRNMMRESLHIKKEAFEAWRRVIEVALAscpADIFPRETRQTVISEILQDLLCRI-----ADESAIAELTSPVSGVILCLMAHL 1379 **************************************9999***********************.....************************ PP Nup192 1363 rasikkdeeqkegn....................lsserLlqlfktciegIlsse.stqkLRsdlYvllnkyLqriv............eslsl 1423 r+++ + ++ + + l++ +++k +ie +l+s+ + q +R++lY++l+ ++q + + lsl FUN_001068-T1 1380 RQCTISLNSAT--ApisipesfggskslqqsgssLPVGASVAILKGLIETVLRSGgGLQRVRANLYAALMYFMQTAPetqetkekgvmeNVLSL 1471 ****9998888..33458889999**********9999*****************9*******************3345556666666544444 PP Nup192 1424 ke.eslkkeilqviksagekLieviCnDaitgegtcritalllLdsLvelassnksnfilellaknnyLlllvrslkrtdeelrevlkpdpesl 1516 +s + il v++s+ge +++++C+D+++g+++ r++a++lLd++++++ +++++l++++ ++yL ++ ++l + d +l+++l+p+pe l FUN_001068-T1 1472 YPgQSWDTSILPVLSSYGEPFMDAVCRDSCDGHDVGRMLAFSLLDAIIAVD---WQQRWLNYVSIKGYLRHMTEALPHEDHILQSMLDPSPEPL 1562 445799********************************************8...9999************************************ PP Nup192 1517 dallyetafkaklalLiriAqtreGAqqLlqnelfsvleeskflaidPDlGl............kinsldnplslsdaln.....gesyfellv 1593 +al +++++k+al+ riAq+ eGA+ Llq++l+s l+e++fl+++P+ + +++++ + + +e+y++ll+ FUN_001068-T1 1563 KAL---YIYESKMALFARIAQSFEGAKVLLQAGLLSRLAECSFLDQRPEQERiglsgslyaydqNMSEVTQD-------SfvpsvMERYRQLLM 1646 ***...*******************************************95445577666555433333333.......1445556******** PP Nup192 1594 pvlqLitaillSlGssnksaieqvrklLkehrklvvgvLKRdalleskigkaeeeegLkelaklfvllatl 1664 p+l++i ail+SlGs++k+a+++++++ ++h +++v++L +d + ++ g +L+el ++ +++++ FUN_001068-T1 1647 PALKVILAILTSLGSQHKEASIKALHFVVSHIDVFVSIL-QDRQAVHTSG------SLQELCLATGIICNM 1710 ***************************************.9998888888......*************86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2070 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 958 (0.0375024); expected 510.9 (0.02) Passed bias filter: 759 (0.0297123); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.64u 0.42s 00:00:01.06 Elapsed: 00:00:00.45 # Mc/sec: 18665.98 // Query: FUN_001069-T1 [L=336] Description: FUN_001069 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 792 (0.0310041); expected 510.9 (0.02) Passed bias filter: 697 (0.0272852); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3357.57 // Query: FUN_001070-T1 [L=366] Description: FUN_001070 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.18 11.6 0.0 0.3 10.9 0.0 1.2 1 Herpes_UL36 Herpesvirus UL36 tegument protein Domain annotation for each model (and alignments): >> Herpes_UL36 Herpesvirus UL36 tegument protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 1.2e-05 0.3 64 120 .. 163 220 .. 147 226 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 1.2e-05 Herpes_UL36 64 etvlafNPYtaensrllPPlallksitWidaFs...aaAdtytklFgvsvekllaLlria 120 +tv+ fN +t++ ++ lPP ++++ W ++ ++Ad++ ++ ++L+ri+ FUN_001070-T1 163 DTVFGFNGFTPQEMKKLPPFRVFEQ--WLLDYEpalGVADYWRLTAAEAIQRRKTLCRIN 220 89*******************9995..776665222678888777777788888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (366 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 717 (0.0280681); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3595.72 // Query: FUN_001071-T1 [L=670] Description: FUN_001071 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-18 65.3 1.8 7.4e-11 42.7 0.1 4.0 3 EF-hand_7 EF-hand domain pair 3.1e-13 48.7 2.3 0.0026 17.8 0.0 5.2 6 EF-hand_6 EF-hand domain 6.4e-12 44.6 7.9 0.00094 19.1 0.2 5.5 7 EF-hand_1 EF hand domain 1.9e-09 37.8 0.0 3.5e-09 37.0 0.0 1.3 1 PH_CAYP2 Calcyphosin-2 PH domain 1.5e-08 34.2 0.3 0.016 15.2 0.2 3.6 3 EF-hand_5 EF hand 2.5e-05 25.1 0.2 0.035 15.0 0.0 3.8 4 EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain 0.0011 20.3 0.0 0.0066 17.8 0.0 2.3 2 EF-hand_11 EF-hand domain 0.0016 18.8 0.0 0.0037 17.6 0.0 1.6 1 DM10_dom DM10 domain 0.0082 16.9 0.0 0.043 14.6 0.0 2.3 2 SPARC_Ca_bdg Secreted protein acidic and rich in cysteine C ------ inclusion threshold ------ 0.014 15.8 0.2 0.1 13.1 0.2 2.3 1 EH EH domain 0.063 13.5 0.0 2.7 8.3 0.0 3.1 3 EF-hand_8 EF-hand domain pair 0.13 12.8 0.0 22 5.7 0.0 3.0 2 EF-hand_10 EF hand Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 2.6e-06 0.0056 4 44 .. 507 545 .. 505 547 .. 0.80 2 ! 42.7 0.1 3.5e-14 7.4e-11 1 66 [. 540 603 .. 540 604 .. 0.94 3 ? 3.9 0.0 0.045 96 17 41 .. 636 659 .. 632 666 .. 0.56 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 2.6e-06 EF-hand_7 4 lkeaFkllDsdgdGyldveelkkllrkleegeplsdeevee 44 l + F+ +D++gdG ld++el ++l+ +++ + +e +e+ FUN_001071-T1 507 LGQHFRRMDQSGDGVLDRQELLRALH--TYHIQIPEEVLED 545 6789****************999**9..5666666666665 PP == domain 2 score: 42.7 bits; conditional E-value: 3.5e-14 EF-hand_7 1 eeklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 ee l+++++ lD++gdG+ld+ e+ + ++ +e +++++ v+++f+++D++k+G ++++ + ++y FUN_001071-T1 540 EEVLEDLWNVLDVNGDGFLDYGEFSRGFI--GEMNEFRKSLVRKVFRKLDPSKSGIVNLNNMRKFY 603 68899******************887777..*****************************999998 PP == domain 3 score: 3.9 bits; conditional E-value: 0.045 EF-hand_7 17 Gyldveelkkllrkleegeplsdee 41 G ++++e+++++++ ++g++ sdee FUN_001071-T1 636 GQVTYAEFEDYYEGVSLGFE-SDEE 659 55566666666665555555.5555 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 2.4 5e+03 14 25 .. 368 379 .. 364 379 .. 0.86 2 ? -2.6 0.0 4.7 1e+04 5 14 .. 438 447 .. 437 447 .. 0.86 3 ! 17.8 0.0 1.2e-06 0.0026 4 28 .. 509 533 .. 507 535 .. 0.90 4 ! 15.3 0.1 8.1e-06 0.017 2 26 .. 543 567 .. 542 571 .. 0.90 5 ! 10.1 0.0 0.00038 0.8 2 25 .. 579 602 .. 578 606 .. 0.91 6 ? -1.2 0.0 1.6 3.5e+03 14 27 .. 635 648 .. 634 653 .. 0.79 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 2.4 EF-hand_6 14 dGyisleElraa 25 d++++l E+ ++ FUN_001071-T1 368 DNTLTLYEFHQF 379 899******875 PP == domain 2 score: -2.6 bits; conditional E-value: 4.7 EF-hand_6 5 aFklfDkdgd 14 +F++ D+d + FUN_001071-T1 438 VFRICDVDEN 447 7*****9976 PP == domain 3 score: 17.8 bits; conditional E-value: 1.2e-06 EF-hand_6 4 eaFklfDkdgdGyisleElraalrs 28 + F+++D+ gdG ++++El +al + FUN_001071-T1 509 QHFRRMDQSGDGVLDRQELLRALHT 533 67********************975 PP == domain 4 score: 15.3 bits; conditional E-value: 8.1e-06 EF-hand_6 2 lreaFklfDkdgdGyisleElraal 26 l+++++++D++gdG++++ E+ + + FUN_001071-T1 543 LEDLWNVLDVNGDGFLDYGEFSRGF 567 7899*****************8765 PP == domain 5 score: 10.1 bits; conditional E-value: 0.00038 EF-hand_6 2 lreaFklfDkdgdGyisleElraa 25 +r++F+++D ++G ++l+ +r++ FUN_001071-T1 579 VRKVFRKLDPSKSGIVNLNNMRKF 602 589****************99987 PP == domain 6 score: -1.2 bits; conditional E-value: 1.6 EF-hand_6 14 dGyisleElraalr 27 +G++++ E+ ++ + FUN_001071-T1 635 KGQVTYAEFEDYYE 648 699******99876 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 8.8 1.9e+04 14 24 .. 368 378 .. 368 379 .. 0.82 2 ? -2.8 0.0 4.3 9.1e+03 5 13 .. 438 446 .. 438 447 .. 0.83 3 ! 15.5 0.0 5.9e-06 0.013 6 27 .. 511 532 .. 511 534 .. 0.93 4 ! 19.1 0.2 4.4e-07 0.00094 2 25 .. 543 566 .. 542 569 .. 0.90 5 ! 9.1 0.0 0.00068 1.4 2 25 .. 579 602 .. 578 604 .. 0.89 6 ? 0.3 0.0 0.42 9e+02 15 25 .. 636 646 .. 634 649 .. 0.85 7 ? -1.0 0.0 1.1 2.4e+03 20 28 .. 658 666 .. 656 667 .. 0.84 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 8.8 EF-hand_1 14 dGkIdfeEfke 24 d ++++ Ef + FUN_001071-T1 368 DNTLTLYEFHQ 378 7799999*987 PP == domain 2 score: -2.8 bits; conditional E-value: 4.3 EF-hand_1 5 iFrefDkDg 13 +Fr+ D+D FUN_001071-T1 438 VFRICDVDE 446 699***996 PP == domain 3 score: 15.5 bits; conditional E-value: 5.9e-06 EF-hand_1 6 FrefDkDgdGkIdfeEfkellk 27 Fr +D+ gdG +d++E++++l FUN_001071-T1 511 FRRMDQSGDGVLDRQELLRALH 532 99*****************986 PP == domain 4 score: 19.1 bits; conditional E-value: 4.4e-07 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkel 25 l+++++++D++gdG++d+ Ef + FUN_001071-T1 543 LEDLWNVLDVNGDGFLDYGEFSRG 566 7899*****************876 PP == domain 5 score: 9.1 bits; conditional E-value: 0.00068 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkel 25 ++++Fr++D ++G ++++ ++++ FUN_001071-T1 579 VRKVFRKLDPSKSGIVNLNNMRKF 602 799**************9988765 PP == domain 6 score: 0.3 bits; conditional E-value: 0.42 EF-hand_1 15 GkIdfeEfkel 25 G++++ Ef ++ FUN_001071-T1 636 GQVTYAEFEDY 646 9*******875 PP == domain 7 score: -1.0 bits; conditional E-value: 1.1 EF-hand_1 20 eEfkellkk 28 eEf +++++ FUN_001071-T1 658 EEFTAMMRN 666 9******86 PP >> PH_CAYP2 Calcyphosin-2 PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.0 0.0 1.6e-12 3.5e-09 42 147 .. 357 456 .. 339 471 .. 0.83 Alignments for each domain: == domain 1 score: 37.0 bits; conditional E-value: 1.6e-12 PH_CAYP2 42 lrsfvGlafledstfalyedhkigkstkplPflrravyhcayGerkGqpylPeidlfPGavlfvryeeaenaPeplrrflehtkgvlririlsvds 137 r+ G+ f d t lye h+ g+ +++lPf++r y + G+++Gqpy +d++ G l ++++ P+ + + v+ ri+ vd+ FUN_001071-T1 357 HRELNGFFFSADNTLTLYEFHQFGTRSSALPFIQRGSYSHVQGKKRGQPYT-LLDIYVGGSLSFMTASQASLPQTVS-----SCPVVVFRICDVDE 446 58899*********************************************7.5999998887655555555666554.....45688889999999 PP PH_CAYP2 138 ekrqraleae 147 +++++ l ++ FUN_001071-T1 447 NAKETQLFEN 456 9888777665 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 1.2e-05 0.026 5 23 .. 511 529 .. 509 532 .. 0.90 2 ! 15.2 0.2 7.7e-06 0.016 6 24 .. 548 567 .. 543 568 .. 0.86 3 ? -1.0 0.0 0.96 2.1e+03 2 14 .. 580 592 .. 579 597 .. 0.79 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.2e-05 EF-hand_5 5 FraiDlNgDGkIskeELkr 23 Fr +D gDG ++++EL r FUN_001071-T1 511 FRRMDQSGDGVLDRQELLR 529 *****************77 PP == domain 2 score: 15.2 bits; conditional E-value: 7.7e-06 EF-hand_5 6 raiDlNgDGkIskeELkr.l 24 + +D+NgDG+++ E+ r + FUN_001071-T1 548 NVLDVNGDGFLDYGEFSRgF 567 689*************9855 PP == domain 3 score: -1.0 bits; conditional E-value: 0.96 EF-hand_5 2 kdtFraiDlNgDG 14 +++Fr++D ++G FUN_001071-T1 580 RKVFRKLDPSKSG 592 679*****77777 PP >> EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 3.8 8.1e+03 27 59 .. 350 378 .. 345 387 .. 0.71 2 ! 15.0 0.0 1.6e-05 0.035 13 64 .. 484 534 .. 475 540 .. 0.78 3 ? 5.0 0.0 0.02 42 34 59 .. 540 565 .. 534 586 .. 0.85 4 ? 0.2 0.0 0.62 1.3e+03 34 70 .. 576 612 .. 565 635 .. 0.70 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 3.8 EF-hand_FSTL1 27 lekgksyrellekyFkavDknkdkkldskElle 59 +++g + ++ l+ +F + D ++l E+ + FUN_001071-T1 350 TKNGRDAHRELNGFFFSAD----NTLTLYEFHQ 378 5667778888888888887....5566666655 PP == domain 2 score: 15.0 bits; conditional E-value: 1.6e-05 EF-hand_FSTL1 13 liewlkeevekqsllekgksyrellekyFkavDknkdkkldskEllelvekn 64 + e +++ v+k +l++++++ l ++F+++D++ d+ ld++Ell+ +++ FUN_001071-T1 484 VLENVQRLVKK-QLQNRAVKTLMGLGQHFRRMDQSGDGVLDRQELLRALHTY 534 55556665555.5777888888899*********************998855 PP == domain 3 score: 5.0 bits; conditional E-value: 0.02 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskElle 59 +e+le+ ++ +D n d++ld E+ + FUN_001071-T1 540 EEVLEDLWNVLDVNGDGFLDYGEFSR 565 68999******************975 PP == domain 4 score: 0.2 bits; conditional E-value: 0.62 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllelveknetvael 70 ++l+ k F+++D +k + ++ + + ++ +++ + l FUN_001071-T1 576 KSLVRKVFRKLDPSKSGIVNLNNMRKFYCTKKHPKVL 612 5677899******999999999998876655544444 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 4.5 9.6e+03 56 70 .. 247 261 .. 242 268 .. 0.79 2 ! 17.8 0.0 3.1e-06 0.0066 16 81 .. 501 566 .. 486 574 .. 0.82 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 4.5 EF-hand_11 56 eqfdrlwselpvnak 70 q+dr ws p + FUN_001071-T1 247 SQYDRPWSTQPATQR 261 69******9998765 PP == domain 2 score: 17.8 bits; conditional E-value: 3.1e-06 EF-hand_11 16 ashyhaivqefenfdtlksntvsree.fraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsk 81 + q f +d + r+e +ra+ t ++qi +e ++ lw+ l vn g l y +f FUN_001071-T1 501 VKTLMGLGQHFRRMDQSGDGVLDRQElLRALHTYHIQI-PEEVLEDLWNVLDVNGDGFLDYGEFSRG 566 4555677899999999999999999945*********9.6899*******************99655 PP >> DM10_dom DM10 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 1.7e-06 0.0037 10 93 .. 340 421 .. 335 447 .. 0.81 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 1.7e-06 DM10_dom 10 kvLrFkayldeksespeeeerkfvisyyleDdtieifEpkvrNsGivggkflkRqklpkpgseekeeyytpkdlnvgatvnvfg 93 k rF a++ +k + + +r++ ++ +D+t++ +E ++ + f++R + + +++ + yt d++vg ++++ FUN_001071-T1 340 KRVRFGARIVTK--NGRDAHRELNGFFFSADNTLTLYEFHQFGTRSSALPFIQRGSYSHVQGKKRGQPYTLLDIYVGGSLSFMT 421 668********7..9*************************9877777789*******9944444449***********999987 PP >> SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 2.9 6.2e+03 88 104 .. 433 449 .. 425 459 .. 0.75 2 ! 14.6 0.0 2e-05 0.043 27 111 .. 479 564 .. 454 566 .. 0.79 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 2.9 SPARC_Ca_bdg 88 kCikpflescDankdkk 104 +C ++ cD++++ k FUN_001071-T1 433 SCPVVVFRICDVDENAK 449 68888899999988764 PP == domain 2 score: 14.6 bits; conditional E-value: 2e-05 SPARC_Ca_bdg 27 lkereeekeeleeeekeaeekelkeckeaiawkFnklDtnkdklldksEL.aairap.lvklEkCikpflescDankdkkislkEwc 111 l+er+ e+ ++++k++ ++ ++ ++ +F ++D+ d++ld++EL +a+++ + E+ + + + D+n d+ ++ E+ FUN_001071-T1 479 LQERKV-LENVQRLVKKQLQNRAVKTLMGLGQHFRRMDQSGDGVLDRQELlRALHTYhIQIPEEVLEDLWNVLDVNGDGFLDYGEFS 564 333333.357888888888888888999999******************73567664155569999*************99999986 PP >> EH EH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.2 4.7e-05 0.1 35 62 .. 536 563 .. 509 567 .. 0.81 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 4.7e-05 EH 35 skLeqdqLakiWdlaDidddGkLdfeef 62 ++++++L+ +W++ D++ dG Ld ef FUN_001071-T1 536 IQIPEEVLEDLWNVLDVNGDGFLDYGEF 563 46789********************999 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.0013 2.7 2 47 .. 519 563 .. 518 565 .. 0.90 2 ? 0.6 0.0 0.32 6.8e+02 22 45 .. 574 597 .. 568 600 .. 0.85 3 ? -1.1 0.0 1.1 2.2e+03 1 32 [. 634 665 .. 634 666 .. 0.64 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0013 EF-hand_8 2 kgvItresLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeF 47 +gv++r +L r+l + +q + e+ + +l +++D +gdG ++ eF FUN_001071-T1 519 DGVLDRQELLRALhTY-HIQ-IPEEVLEDLWNVLDVNGDGFLDYGEF 563 89***********666.777.*******************9987777 PP == domain 2 score: 0.6 bits; conditional E-value: 0.32 EF-hand_8 22 lsedevdtlfrefDtDgdGkisfe 45 + ++ v+ +fr +D ++G+++++ FUN_001071-T1 574 FRKSLVRKVFRKLDPSKSGIVNLN 597 678889999************976 PP == domain 3 score: -1.1 bits; conditional E-value: 1.1 EF-hand_8 1 ekgvItresLkrilalLglqdlsede.vdtlfr 32 ekg++t +++ + + ++l+ ++ de +++++r FUN_001071-T1 634 EKGQVTYAEFEDYYEGVSLG-FESDEeFTAMMR 665 57778888887766555666.544444888876 PP >> EF-hand_10 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.038 82 27 43 .. 511 527 .. 508 532 .. 0.90 2 ? 5.7 0.0 0.01 22 23 47 .. 579 603 .. 558 605 .. 0.85 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.038 EF-hand_10 27 FqkcDkSksgrLegeEi 43 F++ D+S +g L+ +E+ FUN_001071-T1 511 FRRMDQSGDGVLDRQEL 527 9************9997 PP == domain 2 score: 5.7 bits; conditional E-value: 0.01 EF-hand_10 23 ArkLFqkcDkSksgrLegeEieeFy 47 rk+F+k D Sksg + + + +Fy FUN_001071-T1 579 VRKVFRKLDPSKSGIVNLNNMRKFY 603 689***********99999999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (670 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1194 (0.046741); expected 510.9 (0.02) Passed bias filter: 835 (0.0326874); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6486.57 // Query: FUN_001072-T1 [L=155] Description: FUN_001072 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.23 11.5 0.4 0.31 11.0 0.4 1.1 1 ICEA ICEA Protein Domain annotation for each model (and alignments): >> ICEA ICEA Protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.4 1.2e-05 0.31 150 207 .. 9 68 .. 4 77 .. 0.81 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 1.2e-05 ICEA 150 ickvcketnkrwsaknlkgnpyafyegdenytqelgcvg.cyqydpveyrkesvi.kiak 207 c c++ + g ya y+gd+n + +g + dp++y kes + ki++ FUN_001072-T1 9 YCSCCRNCACCDFDSTVCGPRYARYRGDDNDVDLENIIGdLLELDPLQYDKESGMdKISH 68 588899988888888999************9988888883579********996527765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (155 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 962 (0.037659); expected 510.9 (0.02) Passed bias filter: 433 (0.0169505); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1514.43 // Query: FUN_001073-T1 [L=119] Description: FUN_001073 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 815 (0.0319045); expected 510.9 (0.02) Passed bias filter: 340 (0.0133098); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1207.56 // Query: FUN_001074-T1 [L=80] Description: FUN_001074 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.074 13.3 0.1 0.089 13.1 0.1 1.1 1 DUF6323 Family of unknown function (DUF6323) Domain annotation for each model (and alignments): >> DUF6323 Family of unknown function (DUF6323) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.1 3.5e-06 0.089 55 81 .. 17 43 .. 13 58 .. 0.90 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3.5e-06 DUF6323 55 spyisqenYvetleeLqeiFYylknet 81 +y sqe+ ++t ++L ++FY+ kn FUN_001074-T1 17 GKYFSQEEIANTRNKLCDLFYQAKNTK 43 68***********************75 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (80 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1174 (0.0459581); expected 510.9 (0.02) Passed bias filter: 641 (0.025093); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 829.21 // Query: FUN_001075-T1 [L=470] Description: FUN_001075 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-67 228.8 25.2 1.5e-67 228.5 25.2 1.0 1 Aa_trans Transmembrane amino acid transporter protein ------ inclusion threshold ------ 2.7 9.0 7.1 0.34 11.9 1.7 2.4 2 TMD_POM152 Nucleoporin POM152, N-terminal transmembrane doma Domain annotation for each model (and alignments): >> Aa_trans Transmembrane amino acid transporter protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 228.5 25.2 1.2e-71 1.5e-67 3 409 .. 70 462 .. 68 464 .. 0.95 Alignments for each domain: == domain 1 score: 228.5 bits; conditional E-value: 1.2e-71 Aa_trans 3 ssalqavlnlikaiiGaGvLsLPyAfkqlGlipGlillllvglislytlllLvkcskeva.....vkgkrnksYgdlgrrllGkkgrlliafaill 93 ++++a++++i ++ G+GvL+LPyA+ +G+ G+++l+l+ l+s y+ +L + ++ ++ ++g+ ++ Y ++g++++G+++ +++ ++i + FUN_001075-T1 70 LTIFTAAIFIIGEMAGSGVLALPYAIVFAGWT-GIAMLILCCLASGYCGMVLGRSWTLLRerhraYRGHVRYPYPAIGEKAYGRWASIAVTVCIQV 164 6899****************************.************************9998888889999999*********************** PP Aa_trans 94 nliGvsvsylilagdnlpaifesffdt.lelskvvfilifglilipLsfipnlsalsilSllaavssliyivilvlvvaekvvltakgvseetvkt 188 +l+Gv+v++lila+ n+++++e +++ e+++ ++ li +++l+pLs++ ++++ +++ a +++++++v++ + +a +++ + k+v++ tv FUN_001075-T1 165 TLFGVAVVFLILAAGNMSHLIELKMSDdSETELRIWLLICFAVLFPLSWLGTPKEFWGIAVGASLATAVACVMICVCIALDMPDDLKSVEQPTV-- 258 **********************988878****************************************99**********************98.. PP Aa_trans 189 niklarlflaigiivFAfeghavlleiqnemkkPskfkkmtkvlllaiiivtvlyiliGlvGYlaFGdevkgnillnlpkse.....vlidivnll 279 ++ +f+a+g+i F+f+g+ ++++iq++mk s f+ +++la+i+v+ +y ++ +G++ +G +++ nil+ + ++ v div +l FUN_001075-T1 259 --HFESFFSAFGTILFSFGGASTFPTIQTDMKRSSRFP---VSVVLAYIAVIGMYLPVSILGFVSYGKDIEPNILDVIGHNQhhlskVTVDIVLAL 349 ..5559********************************...8*************************************9999*9999999999** PP Aa_trans 280 lvlhvllsfplqlfpivqvlenllfkkeaeekasekknrkskllrlvirlllvvitlliAilvpflgkllslvGatscaplsfilPalfhlklikt 375 ++lh++ sf+++l p+ q +e l+ ++k+ r ++r++l+ ++l ++ l+p++g +lsl+G ++++l+f++P+lf+l+l ++ FUN_001075-T1 350 ITLHLMSSFVIVLNPVSQQFEEFLNI-----------PQKFCFKRCLLRSALMCFILGVSELIPKFGLILSLIGGSTITLLTFVFPCLFYLRLEQN 434 ************************65...........6777789*************************************************999 PP Aa_trans 376 kkksleklakkkildviciviglllmalgvagli 409 + ++ +l + +i igl+ +++++ +i FUN_001075-T1 435 LSLHIK------VLLYEIIAIGLFGGVASTYSAI 462 874444......4457788999998888888766 PP >> TMD_POM152 Nucleoporin POM152, N-terminal transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 1.7 2.7e-05 0.34 9 59 .. 169 219 .. 166 245 .. 0.82 2 ? -3.5 0.3 1.7 2.2e+04 66 81 .. 346 361 .. 342 364 .. 0.64 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 2.7e-05 TMD_POM152 9 alslfvllqawKlydllllkseeeslwlllkWllidllflllLpllrIPrL 59 ++ +f++l a + +l+ lk +++s + l+ Wlli +++l+ L++l P+ FUN_001075-T1 169 VAVVFLILAAGNMSHLIELKMSDDSETELRIWLLICFAVLFPLSWLGTPKE 219 6789999**************************************988875 PP == domain 2 score: -3.5 bits; conditional E-value: 1.7 TMD_POM152 66 vlllilllallnlllf 81 vl+li l+++ ++++ FUN_001075-T1 346 VLALITLHLMSSFVIV 361 5666666666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (470 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1029 (0.0402819); expected 510.9 (0.02) Passed bias filter: 508 (0.0198865); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4569.52 // Query: FUN_001076-T1 [L=978] Description: FUN_001076 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-157 525.9 16.5 1.9e-157 525.3 16.5 1.3 1 Anoctamin Calcium-activated chloride channel 1.9e-71 240.9 0.1 2.8e-71 240.4 0.1 1.3 1 Anoct_dimer Anoctamin, dimerisation domain Domain annotation for each model (and alignments): >> Anoctamin Calcium-activated chloride channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 525.3 16.5 1.5e-161 1.9e-157 1 460 [] 372 959 .. 372 959 .. 0.94 Alignments for each domain: == domain 1 score: 525.3 bits; conditional E-value: 1.5e-161 Anoctamin 1 irdyFGekiAlYFaflgfYtkwLlppavvGllvflyg.ati............................................lfdneltvffa 51 irdyFGeki++YFa+lgfYt +L+p+a++Gl++ +yg +++ +fdne+tv+fa FUN_001076-T1 372 IRDYFGEKIGIYFAWLGFYTAMLVPAALMGLICVIYGaVKVgsyipvrdicdegkekdypmcprcdqrcpywllsdtciyskvayVFDNEFTVVFA 467 9***********************************99999******************************************************* PP Anoctamin 52 ifmvlWatlflefWkrkeaelayrWgvtgfeeee.eprpefkgekers..epvtgekekyypswkrrlrryllslpvvlllial...lvlgviilr 141 ifm+lWat+flefWkr++ae+ay+W++ g+e+ee +prpe+++ + ++ +p+t+ e+y k +++r+++s+++vl++++l +v++v+++r FUN_001076-T1 468 IFMSLWATMFLEFWKRRQAEIAYEWDLLGYEDEEeQPRPEYEAAASNTrlNPITKVDEPYIAVGK-KIPRFVCSFSFVLFMLVLvlvAVVAVVVYR 562 *****************************99666599******9998899***********9888.************977666455777799999 PP Anoctamin 142 vfaiealisevyegpsk..silsflptvlnlviililnkvyeklAkkltdwEnhrtqseyenslilKvflfqfvnsylslfyiaFvkgrfvgypgk 235 + ++++l+ + + + + ++s +++++nl+ii+ilnk+ye+lA+ lt+wE++rtq+e e+ +++K++lfqf+n+y+slfyiaF+k++ g+pg+ FUN_001076-T1 563 AALFAVLAAQGDYNVGAvnIATSATAALINLIIIMILNKFYERLAEILTRWEMPRTQTELEDIFTFKMYLFQFLNFYSSLFYIAFFKQNP-GRPGD 657 6666888887777777786699****************************************************************9976.68*** PP Anoctamin 236 ylklf..lrleecepegcleeLrqqlaiilvtkqiinnilevllPylkrklkkkkkkkkkkeeesksekdeeeekeklervekeyeleeydv...l 326 +++f +r+eec+p gcl eL ql +i+v+kqi+nn++ev++P+l + +k+ ++ + e + ++++r+e +y+l +y v + FUN_001076-T1 658 FNRIFgkYRQEECNPAGCLFELLLQLSVIMVGKQIFNNFIEVIVPKLQNWWKR-RQ-N--I---------ETPDLTEYTRWELDYDLTTYPVhglF 740 *********************************************87433322.11.1..1.........12244679*************55966 PP Anoctamin 327 ddylemviqfGyvtlFsaafPlapllallnniieirldafklvtelrRpvperadsIGiWlkilellsvlavitnaaliaftsdf........... 411 ++ylemviqfG+vtlF +afPl p++al+nn++eirlda+k+v++++Rp++ ra++IGiW++il+ ++ ++v++n ++iaf s+f FUN_001076-T1 741 YEYLEMVIQFGFVTLFISAFPLGPFFALINNLLEIRLDAYKFVVVFQRPMAARAQDIGIWYTILKSVTKISVVVNGFVIAFVSEFvprlyytlglg 836 ************************************************************************************************ PP Anoctamin 412 ..........................................................................elseqywsllalllafvivleh 433 e+s+ yw++la +l+fv+++ h FUN_001076-T1 837 ndslegfvnstlscfvvnefpakerpsgtgkdvlwehfnnnscgfgqptcrfrgyyerpfitiegqtldnprkyEFSTAYWHILASKLFFVLAFLH 932 **************************************************************************9999****************** PP Anoctamin 434 vvlllkfliawlipdvpewvrkerkre 460 +v++l +iaw+ipdvp++v++++kre FUN_001076-T1 933 IVYGLTAIIAWIIPDVPKEVSNQVKRE 959 ************************996 PP >> Anoct_dimer Anoctamin, dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 240.4 0.1 2.2e-75 2.8e-71 1 221 [] 144 369 .. 144 369 .. 0.95 Alignments for each domain: == domain 1 score: 240.4 bits; conditional E-value: 2.2e-75 Anoct_dimer 1 yFrDgkrriDfVLvyeeed.keeeeeekkeekrkkFeenLkkegLelEeeeke..ekkklvFvkihapwevlsryAeilklkmplkevekkenele 93 +FrDgkrriD++L+ye ++ k+e+ ++k+eekr++Fe+nL k+ LelE e e +++k+ ++k+hapw+vl++ Ae++ +kmp+ke ++++++ FUN_001076-T1 144 FFRDGKRRIDYILAYEIDTgKDEDWQQKREEKRSEFEANLVKAHLELEAEGIElsSNGKTAYIKVHAPWKVLAEGAEEMLMKMPIKE---NDMDTR 236 8****************996677779999**********************99866******************************7...778888 PP Anoct_dimer 94 eelksllekl..kklfeldekkikeekdyftapfsrdkeelFdi.edketfftsaeRsrivyeiLertkfkkekkkefGierLlkegvytaaYPLH 186 + ++++ + +++fel ++ +e+++yft++f+rdk e F+i e++++fft a+Rsriv++iL +t++ e+k+++Gi rL+ +g ytaaYPLH FUN_001076-T1 237 DWAERCFGGIgiRSPFELRADELPEQPNYFTCAFRRDKLESFLIpENRDDFFTYAQRSRIVHRILMKTNY-GERKNQIGIGRLIGNGSYTAAYPLH 331 8888998887779*********************************************************.7899********************* PP Anoct_dimer 187 dgdyekkk...eeeklndRqlLyeeWArlkkwykyQPL 221 +g+y+ ++ ++++n RqlLy++W +l++wyk QPL FUN_001076-T1 332 EGTYQLDEsseAQRPENARQLLYNTWVNLSRWYKVQPL 369 ****9998888999***********************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (978 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1479 (0.0578978); expected 510.9 (0.02) Passed bias filter: 794 (0.0310824); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.43s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 9374.30 // Query: FUN_001077-T1 [L=539] Description: FUN_001077 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-22 78.2 0.1 7e-20 72.0 0.1 2.5 1 CNPase 2',3'-cyclic nucleotide 3'-phosphodiesterase 2.4e-11 44.6 0.0 6e-11 43.3 0.0 1.7 1 AAA_33 AAA domain 1.5e-06 28.4 0.0 2.8e-06 27.5 0.0 1.4 1 KTI12 Chromatin associated protein KTI12 0.00086 20.3 0.0 0.0025 18.8 0.0 1.7 1 AAA_18 AAA domain 0.0032 18.2 0.0 0.0082 16.9 0.0 1.8 1 AAA_17 AAA domain 0.0088 16.4 0.0 0.044 14.1 0.0 2.0 1 nSTAND_NTPase5 Novel STAND NTPase 5 ------ inclusion threshold ------ 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 Zeta_toxin Zeta toxin 0.046 13.9 0.1 0.14 12.3 0.0 1.9 1 nSTAND3 Novel STAND NTPase 3 0.05 13.4 0.1 0.23 11.2 0.0 2.0 2 6PF2K 6-phosphofructo-2-kinase 0.051 14.0 0.0 0.42 11.0 0.0 2.2 2 Vma12 Endoplasmic reticulum-based factor for assemb 0.065 13.5 0.0 0.12 12.6 0.0 1.3 1 AAA_30 AAA domain 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 G-alpha G-protein alpha subunit 0.12 13.2 0.1 1 10.2 0.1 2.5 1 AAA_22 AAA domain 0.13 13.3 0.5 1.1 10.3 0.1 2.7 1 RNA_helicase RNA helicase 0.15 12.1 0.4 0.67 10.0 0.0 2.0 2 NB-ARC NB-ARC domain 0.21 12.5 0.0 0.56 11.1 0.0 1.7 1 AAA ATPase family associated with various cellula Domain annotation for each model (and alignments): >> CNPase 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.0 0.1 4.4e-23 7e-20 4 213 .. 290 539 .] 287 539 .] 0.86 Alignments for each domain: == domain 1 score: 72.0 bits; conditional E-value: 4.4e-23 CNPase 4 yfGwfltkksseklrkagqvfleelgs..lkafkkelkhflstdepkekidlvsy..fgkrppgv..........lhcttkfcdyGkaaGaeeyaq 85 y+Gwfl+++ ++l+ ++++e + + +fk + +++ +++ ke dl+s f+ + lh t+ + + +a+ a+ey FUN_001077-T1 290 YYGWFLSENGVQTLKDRMFEMIDECCEtiTPSFKDDFQKLDNGQDGKESGDLTSQhtFSDTILSTlpcleyiqdkLHVTAFYNKREQANEAHEYVS 385 ***********************987622468********************9752254433222111122233389999999999********** PP CNPase 86 qdvvkksygkaftlsisalfvtpktvGarvelseqqlklwpadvdk...........................lsasdslpkGsrahvtlGcaadv 154 +v+ + g++ ++ i a +tp+t+ arv+l+ qq++l+ + l +l kG ahvtl dv FUN_001077-T1 386 SSAVRDALGSVGRMVIIAWTITPRTITARVKLNSQQMELYDHQDYLsheelsassqtcpqtsdystrplaytdLILKPTLGKGDTAHVTLSRRGDV 481 ***************************************975432246789999***********9998877766677899*************** PP CNPase 155 eavqtGldlleivklekagskGeevgelsrGkllslGeGrwmlslakkievkaifsgyy 213 +v+ +dl +++ le +kG e ls+G + G w + l +++ v +f+gyy FUN_001077-T1 482 TPVRGRFDLRDLIGLEL-ANKGYEEHRLSQGVARRYNGGIWAVYLDEPVIVDVLFTGYY 539 ***************65.5899999*********************************9 PP >> AAA_33 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.3 0.0 3.7e-14 6e-11 2 141 .. 151 284 .. 150 286 .. 0.88 Alignments for each domain: == domain 1 score: 43.3 bits; conditional E-value: 3.7e-14 AAA_33 2 illvGlsGsGKstlarrlleelg..avllssDtlrkrlageeaksksdlteatertyallkklaekalragrp.vilDaTnlrreerarllalare 94 ++l+Gl+GsGKst+a+++ + g a + s D++r + ge + +e+ + + ++ a++a+ ++rp vi+D Tn+r+e +++++ar FUN_001077-T1 151 FILRGLPGSGKSTVAKQIKQVYGdlALICSADDFRMTDSGEYF----WKPEEYDMSHLKCEEKARQACYNERPvVIIDDTNIRKELLYWYIDAARS 242 799***************99999999999****9888777544....44566677777889************8999******************* PP AAA_33 95 lgvpvrivvveapeetlkerlaaRaeagedpsevpeavldamkarfe 141 +++ v++v ++ ++ + l + ++ +v+++ l++m ++f+ FUN_001077-T1 243 YDYFVVLVEPKTTWRYSISDLILKTHH-----QVSKEILEEMWSTFD 284 ***************999999999998.....788888888887776 PP >> KTI12 Chromatin associated protein KTI12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.0 1.8e-09 2.8e-06 5 139 .. 152 285 .. 149 292 .. 0.71 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 1.8e-09 KTI12 5 vltGlPssGKstvakeLakklee.....kklsvvvisdeslgiekes.ykdskkekklRsslrsavkrdLsk.etiVIvDslnyikgfRyeLycia 93 +l GlP sGKstvak++++ + + + + +++ + +++ ++ + + ++++++ + +VI+D++n k y + +a FUN_001077-T1 152 ILRGLPGSGKSTVAKQIKQVYGDlalicSADDFRM-------TDSGEyFWKPEEYDMSHLKCEEKARQACYNeRPVVIIDDTNIRKELLYWYIDAA 240 899****************9877333333333333.......3343434555555555666666666665440569******************** PP KTI12 94 keakttycvvyvvapldllvkwneereekeeyekelldaLiqryee 139 ++++ +++v +++ +++ ++++ + +ke+l+++ + +++ FUN_001077-T1 241 RSYDYFVVLVEPKTTWRYSISDLILKTHH-QVSKEILEEMWSTFDQ 285 **999999999999976666666555544.6788888888888876 PP >> AAA_18 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 1.5e-06 0.0025 2 95 .. 152 246 .. 151 257 .. 0.56 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 1.5e-06 AAA_18 2 litGtpGvGKttlareLserlgf.gdnvrdlakenglvlsddeetdeskrldedklaklldeleelas..leeggnlvidghlaelf.perlrdlv 93 ++ G+pG+GK+t+a+++++ + + + a++ + +s + + + +e+++++ l++ e++ + ++e +++id+ + + ++++d++ FUN_001077-T1 152 ILRGLPGSGKSTVAKQIKQV--YgDLALICSADDFRMTDSGEYF-----WKPEEYDMSHLKCEEKARQacYNERPVVIIDDTNIRKElLYWYIDAA 240 578**************554..4455555555555555555555.....44444444444444444334457777778887654444144444444 PP AAA_18 94 v....v 95 + + FUN_001077-T1 241 RsydyF 246 466663 PP >> AAA_17 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 5.1e-06 0.0082 2 29 .. 155 183 .. 154 224 .. 0.78 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 5.1e-06 AAA_17 2 GvPGsGKgtqakklaekl.glphlsaGdl 29 G+PGsGK+t+ak++++ + +l + d FUN_001077-T1 155 GLPGSGKSTVAKQIKQVYgDLALICSADD 183 9***************9954555555555 PP >> nSTAND_NTPase5 Novel STAND NTPase 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 2.8e-05 0.044 40 140 .. 147 259 .. 139 264 .. 0.75 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.8e-05 nSTAND_NTPase5 40 kprvvlvlGpaGeGKtta...Lmqvavela.........aakgwtvlwrdedaeilsdk.eellel.kekekwllvvDdadlvadelakllkkle 120 ++ +++++G G+GK+t+ ++qv +la +++ + +w e+ + + k ee +++ +e+ ++++Dd+++ + l + +++++ FUN_001077-T1 147 SKVIFILRGLPGSGKSTVakqIKQVYGDLAlicsaddfrMTDSGEYFWKPEEYDMSHLKcEEKARQaCYNERPVVIIDDTNIRKELLYWYIDAAR 241 45679999*********933344555566666722333334445557777777777777955555559*************************99 PP nSTAND_NTPase5 121 kegrkvlvllaeRdnewres 140 + + + v+l e ++ wr s FUN_001077-T1 242 SYD--YFVVLVEPKTTWRYS 259 987..7999********976 PP >> Zeta_toxin Zeta toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 3.4e-05 0.054 14 55 .. 146 185 .. 136 187 .. 0.86 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 3.4e-05 Zeta_toxin 14 erPvavllaGqpGAGKtelaellkeelqrqgnvvrldpDelr 55 +++v+ +l G pG+GK+++a+ +k+ ++ +++ +D++r FUN_001077-T1 146 NSKVIFILRGLPGSGKSTVAKQIKQVY--GDLALICSADDFR 185 56789999*****************98..7778888999998 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 8.7e-05 0.14 11 41 .. 141 172 .. 138 226 .. 0.73 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 8.7e-05 nSTAND3 11 leiLeknkvv.iitGepGiGKttlaemLalkl 41 ++ +++ kv+ i+ G pG+GK+t+a+++ + FUN_001077-T1 141 IQFIKNSKVIfILRGLPGSGKSTVAKQIKQVY 172 66677777762567************986555 PP >> 6PF2K 6-phosphofructo-2-kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00015 0.23 4 36 .. 139 171 .. 136 187 .. 0.87 2 ? -1.1 0.0 0.83 1.3e+03 99 131 .. 220 252 .. 211 291 .. 0.85 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00015 6PF2K 4 stvknlknskllivlvGLpargKtyiskkltry 36 +++ knsk++ +l GLp gK++++k++ + FUN_001077-T1 139 RCIQFIKNSKVIFILRGLPGSGKSTVAKQIKQV 171 57777899********************99875 PP == domain 2 score: -1.1 bits; conditional E-value: 0.83 6PF2K 99 vaifDAtNttrerRklilefaeennlkvlfles 131 v i D tN+++e + ++ a++ ++ v+++e FUN_001077-T1 220 VVIIDDTNIRKELLYWYIDAARSYDYFVVLVEP 252 789999*****9999999999999999988885 PP >> Vma12 Endoplasmic reticulum-based factor for assembly of V-ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00026 0.42 64 138 .. 23 113 .. 4 119 .. 0.71 2 ? -0.1 0.0 0.7 1.1e+03 19 96 .. 318 401 .. 312 418 .. 0.55 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00026 Vma12 64 eedevtpaqelkevkrqltlilNilvSvvavavaiwiaarssvgl....................stpaRvllslfvallVavAEvvvyagylrk 138 + d+v + ++++ +t+ + i+ +++ ++a+ i + ++ g + R+ ++l ++l V + vvvya ++ FUN_001077-T1 23 DADDVD----NVDISNDVTMTITIMALIMISTCALHIKSLTVGGYgqgdidrscmvlrlkfgilrMIFRRLAVCLAIGLAVSLTSVVVYALTTKR 113 334444....666666666666666666666666666666665556677888888888888888777889*******************987765 PP == domain 2 score: -0.1 bits; conditional E-value: 0.7 Vma12 19 pspeykallarlraeqeereYqrmikpss.eketledspsp.....faedeeedevt....paqelkevkrqlt..lilNilvSvvavav 96 +p +k+ ++l q+ +e ++++++ + + l + p + ++ +vt ++ +e ++ ++ ++ l Sv ++ FUN_001077-T1 318 ITPSFKDDFQKLDNGQDGKESGDLTSQHTfSDTILSTL--PcleyiQ----DKLHVTafynKREQANEAHEYVSssAVRDALGSVGRMVI 401 58999999999999999999999999955322222222..1222221....222222223344444455544431145555555555555 PP >> AAA_30 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 7.5e-05 0.12 12 42 .. 142 172 .. 139 180 .. 0.89 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.5e-05 AAA_30 12 alltsgdrvqvlvGpAGtGKTtalkalreaw 42 +++++++ + +l G +G+GK+t+ k++++++ FUN_001077-T1 142 QFIKNSKVIFILRGLPGSGKSTVAKQIKQVY 172 56788899********************998 PP >> G-alpha G-protein alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00011 0.18 21 47 .. 148 174 .. 141 193 .. 0.87 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00011 G-alpha 21 evklLllGageSGKsTilkqmkilhkk 47 +v ++l G +SGKsT+ kq+k ++++ FUN_001077-T1 148 KVIFILRGLPGSGKSTVAKQIKQVYGD 174 5788999***************99965 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.1 0.00062 1 5 29 .. 148 172 .. 144 319 .. 0.71 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00062 AAA_22 5 agilvltGesGtGKTtllrrlleql 29 + i +l G +G+GK+t+++++++ + FUN_001077-T1 148 KVIFILRGLPGSGKSTVAKQIKQVY 172 5577899*************99876 PP >> RNA_helicase RNA helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.1 0.0007 1.1 2 59 .. 152 227 .. 151 250 .. 0.66 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0007 RNA_helicase 2 wlyGpsgeGKStlakelakallkkl..................klpkkdsvysrnpeddfw.dgYkgqevviidDfg 59 +l+G +g GKSt+ak+ +k++ +l p++ ++ ++e++ Y++ +vviidD + FUN_001077-T1 152 ILRGLPGSGKSTVAKQ-IKQVYGDLalicsaddfrmtdsgeyfWKPEEYDMSHLKCEEKARqACYNERPVVIIDDTN 227 6899************.666666666677777776666666653333344434333333331556677777777765 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.00042 0.67 18 40 .. 147 170 .. 139 176 .. 0.80 2 ? -0.8 0.1 0.88 1.4e+03 89 115 .. 206 232 .. 194 288 .. 0.55 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00042 NB-ARC 18 lq.ivalvGmgGvGKttLakeifn 40 ++ i l G +G+GK+t+ak+i + FUN_001077-T1 147 SKvIFILRGLPGSGKSTVAKQIKQ 170 45256679*************975 PP == domain 2 score: -0.8 bits; conditional E-value: 0.88 NB-ARC 89 laeklrrlLltkrfllvlDDvweeedw 115 +ek r++ + r ++++DD ++++ FUN_001077-T1 206 CEEKARQACYNERPVVIIDDTNIRKEL 232 667777788888889999986544442 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00035 0.56 2 65 .. 152 225 .. 151 227 .. 0.69 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00035 AAA 2 llyGppGtGKTllakavakelgaefveisgselvsk...........yvgesekklrelfeeakkkapsvifiDE 65 +l G pG GK+++ak + + g + s+ +++ + ++ s k +e ++a ++ +v++iD+ FUN_001077-T1 152 ILRGLPGSGKSTVAKQIKQVYGDLALICSADDFR-MtdsgeyfwkpeEYDMSHLKCEEKARQACYNERPVVIIDD 225 688**************99999777777777777.2246777655555555555555555555555567777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (539 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1276 (0.0499511); expected 510.9 (0.02) Passed bias filter: 1033 (0.0404384); expected 510.9 (0.02) Passed Vit filter: 107 (0.00418869); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.37u 0.42s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 5162.22 // Query: FUN_001078-T1 [L=244] Description: FUN_001078 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00049 20.9 20.5 0.00049 20.9 20.5 3.2 3 Dickkopf_N Dickkopf N-terminal cysteine-rich region ------ inclusion threshold ------ 1.8 9.4 18.7 0.11 13.3 4.9 2.7 3 Prokineticin Prokineticin Domain annotation for each model (and alignments): >> Dickkopf_N Dickkopf N-terminal cysteine-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 20.5 3.8e-08 0.00049 1 50 [. 101 146 .. 101 147 .. 0.94 2 ? -0.4 6.3 0.16 2.1e+03 2 34 .. 158 193 .. 157 195 .. 0.68 3 ? -1.6 0.2 0.39 4.9e+03 23 42 .. 208 214 .. 201 220 .. 0.58 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 3.8e-08 Dickkopf_N 1 eClsDedCgkgkyClssseesvClpcrkrrkrCtrdamCcpgnlCvngvC 50 eC++ + C++g yC+ C++c k + C+++++Cc+g +C +g C FUN_001078-T1 101 ECSEKKPCKEGMYCNIL----YCEKCHKVNVACNSNEQCCKGLVCTFGRC 146 6999**********986....59*************************** PP == domain 2 score: -0.4 bits; conditional E-value: 0.16 Dickkopf_N 2 ClsDedCgkgkyClsssees....vClpcrkrrkrCt 34 C +D+dC++ C + + +C+p+ ++ +C FUN_001078-T1 158 CEKDSDCKDA-CCVLEPTINshlaICKPMLEEYHQCA 193 9999999765.45443332336778888888888885 PP == domain 3 score: -1.6 bits; conditional E-value: 0.39 Dickkopf_N 23 ClpcrkrrkrCtrdamCcpg 42 C pc+ pg FUN_001078-T1 208 CGPCK-------------PG 214 55554.............44 PP >> Prokineticin Prokineticin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.2 0.26 3.3e+03 26 40 .. 102 116 .. 97 122 .. 0.72 2 ? 2.7 4.0 0.017 2.2e+02 15 40 .. 118 143 .. 110 151 .. 0.83 3 ? 13.3 4.9 8.5e-06 0.11 25 89 .. 157 220 .. 154 226 .. 0.83 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.26 Prokineticin 26 cdkdvqcGaglccav 40 c ++ c +g++c + FUN_001078-T1 102 CSEKKPCKEGMYCNI 116 566667888888876 PP == domain 2 score: 2.7 bits; conditional E-value: 0.017 Prokineticin 15 svseaavitGacdkdvqcGaglccav 40 + ++ + ac+ + qc +gl+c+ FUN_001078-T1 118 YCEKCHKVNVACNSNEQCCKGLVCTF 143 5667777889**************85 PP == domain 3 score: 13.3 bits; conditional E-value: 8.5e-06 Prokineticin 25 acdkdvqcGaglccavslwlrslrlctplGkeGdechplshkvpfegkrkhhtcpclpnlvcsrl 89 c+kd+ c + c + l +c p+ +e ++c + + + g++ + pc p+l c++ FUN_001078-T1 157 FCEKDSDCKDACCVLEPTINSHLAICKPMLEEYHQCAAVLYRKIWVGEK-PDCGPCKPGLECVQK 220 59******88766666677778***************998887888876.4678********985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (244 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1206 (0.0472108); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2408.36 // Query: FUN_001079-T1 [L=613] Description: FUN_001079 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-152 510.0 0.0 1.3e-152 509.7 0.0 1.1 1 G_glu_transpept Gamma-glutamyltranspeptidase ------ inclusion threshold ------ 0.04 13.5 0.0 1.9 8.0 0.0 2.4 2 Asparaginase_2 Asparaginase 0.23 11.4 0.0 0.38 10.7 0.0 1.2 1 DUF2417 Region of unknown function (DUF2417) 0.58 10.8 2.1 0.98 10.0 0.4 2.2 3 DUF3333 Domain of unknown function (DUF3333) Domain annotation for each model (and alignments): >> G_glu_transpept Gamma-glutamyltranspeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 509.7 0.0 2e-156 1.3e-152 2 512 .] 98 606 .. 97 606 .. 0.95 Alignments for each domain: == domain 1 score: 509.7 bits; conditional E-value: 2e-156 G_glu_transpept 2 eiLrkGGnAvDAavAaalclgvvepqssGiGGGgfll..vydaktkkveaidaretAPaaatkdmfekkgdsklsktgglavgVPGevagleea 93 + LrkGG+AvDAa+ ++lc+gv++p+s+GiGGGgf+l v +++++++++id+re+AP aa+kdmf +g++ l++ gglavgVPGe++g+e a FUN_001079-T1 98 DLLRKGGSAVDAAIGTMLCVGVMNPESTGIGGGGFMLsvVPQNDGEAAKVIDFREVAPLAASKDMF--HGNDSLASWGGLAVGVPGEIRGYELA 189 68**********************************7436677788889*****************..************************** PP G_glu_transpept 94 hkryGrlpwadllepaiklareGfpvspalaaalaeaeerlkkdpelakiFlpegevlkagellkqpalAktLerlaeeGaeaFYeGelAeklv 187 hk+yG+l+w++l+ aik+areGf+v++++ + l+ ++++ + el k+ +p+g+ lk+g+++ +palA+tL+++a++Ga+aFY+G +A++lv FUN_001079-T1 190 HKKYGKLKWSELFVSAIKIAREGFTVTEHTGRSLKILKQNVIGT-ELGKVVAPKGKLLKEGDKMSNPALANTLQKIADHGADAFYKGPIADSLV 282 ***********************************999996555.4669********************************************* PP G_glu_transpept 188 aelqkngGiltaeDLanYkveveeplsadyrggytvyepppssggivllqiLnilekfdlkslslesaetlhlliEamklayadRsrylgDpdf 281 + ++ +gGilt++DL+ Y++ +e+++++y +gy+v+++p +sgg+vl+ +Lnil++f++++ +++ t+h +iEamk+a+++Rs l D + FUN_001079-T1 283 KAVRSAGGILTKKDLKIYQALEKEAINSTY-KGYQVITTPLPSGGPVLISLLNILDGFKFSEEDQDTSLTYHYMIEAMKFAFGQRSL-LEDSKN 374 ******************************.99**************************99999999********************.****99 PP G_glu_transpept 282 vkvpeelvenllskeyakeraklIndkaaapsseyykaaeaaeedggTthlsvvDaegnaVSltstinleFGsgvvvpgtGilLnnemddfst. 374 +++ ++++lsk++a+ ++++I++++++p ++y+ + ++ ++gT+h+s++ +g+ ++ts++n +FGsg++++ tGilLnnem dfs+ FUN_001079-T1 375 LTDI---IQEMLSKKHANLLRAKISPNQTFP-LSHYGLMTDQAASHGTAHVSAIGPDGDLAAITSSVNGYFGSGIMTK-TGILLNNEMLDFSIp 463 9755...************************.89*******************************************9.*************** PP G_glu_transpept 375 gvenafgldpspanaiePgkRplssmaPtivlk.dgkvkl..vvGaaGGsriisavlqvlvnvldlglslqeavdaprlhhqllpdelevEe.. 463 gv++ g p++an+++PgkRpls maPt vl+ + + +l +G++G+ +ii av+++l+n+l ++ +l+ea+++ r++ l++ ++e+E FUN_001079-T1 464 GVQRVVGAGPPKANFVAPGKRPLSNMAPTAVLHeERRCWLrtSLGGSGSYHIIPAVANTLINILSFNFPLSEAIEKGRIYYGLTSGKTEIEVkr 557 *********************************8666666669*******************************************99999887 PP G_glu_transpept 464 ...gfseevlaeLearghkvkevedsssvvaiqavlkengvleaasDprrdg 512 + +e+++ Le+ gh+v++ + v+ +++++a D+rr g FUN_001079-T1 558 fphKKAKELVQVLENIGHNVTNHSSIADVNGLSYF---KEEIVAHGDSRRGG 606 77777889999999******999998888888887...79999999999975 PP >> Asparaginase_2 Asparaginase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.0 0.0003 1.9 18 52 .. 77 111 .. 63 142 .. 0.83 2 ? 2.8 0.0 0.011 73 125 201 .. 358 436 .. 343 443 .. 0.71 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0003 Asparaginase_2 18 lskereeavrkalkeaveegykvLkeggsaldave 52 +++++++av + +ke+++ g ++L++ggsa+da + FUN_001079-T1 77 SHHTGHAAVVSDVKECADVGLDLLRKGGSAVDAAI 111 4567789999**********************976 PP == domain 2 score: 2.8 bits; conditional E-value: 0.011 Asparaginase_2 125 aeefarelgleevdpetllteerleelkeekkenkkkkvaksvs...aekekaeeeeaklgTvGvValDkegnlAagTST 201 a++fa + +d+ + lt+ +e l +++++ + k++++++ ++ +++ a++gT v a+ +g lAa TS+ FUN_001079-T1 358 AMKFAFGQRSLLEDS-KNLTDIIQEMLSKKHANLLRAKISPNQTfplSHYGLMTDQAASHGTAHVSAIGPDGDLAAITSS 436 666666665555554.6677766666666666666666666666554444456677999*******************96 PP >> DUF2417 Region of unknown function (DUF2417) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 5.9e-05 0.38 2 65 .. 17 75 .. 16 84 .. 0.72 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 5.9e-05 DUF2417 2 rtrLLpkrkkshigeeskegylspddpavspynlwsvrllrwllvvlllitfiwwvlllvsdFv 65 r+ L++++ s+ e +e+ l +++++ + ++l + r +r++++v +++++ + v l+v +F FUN_001079-T1 17 RENLIQHD--SQ---ELEEQSLPDENHHSIARRLKRSRDIRMIIIVSIIFSIAITVALVVDIFT 75 55666543..33...3344444444445777888888**************************7 PP >> DUF3333 Domain of unknown function (DUF3333) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.4 0.00015 0.98 3 40 .. 40 77 .. 38 86 .. 0.91 2 ? -2.8 0.0 1.4 9.2e+03 33 144 .. 261 276 .. 253 281 .. 0.57 3 ? -1.8 0.0 0.67 4.3e+03 77 119 .. 353 398 .. 342 401 .. 0.63 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00015 DUF3333 3 rlkrRyaaErrFrlyGlaAialallfLviLlvsivskG 40 +++rR ++ r r++ +++i++++++ v L+v+i++ FUN_001079-T1 40 SIARRLKRSRDIRMIIIVSIIFSIAITVALVVDIFTGS 77 799*******************************9864 PP == domain 2 score: -2.8 bits; conditional E-value: 1.4 DUF3333 33 lvsivskGltAFqqteikleveldaeeidpkgkedakklatanyeklvkqaleaalpeveerrekrklaellssgaeyqlrdrvladpsligqtvt 128 l +i +G+ AF+ FUN_001079-T1 261 LQKIADHGADAFY----------------------------------------------------------------------------------- 273 4455555555555................................................................................... PP DUF3333 129 vwllasddvDqllKge 144 Kg FUN_001079-T1 274 -------------KGP 276 .............444 PP == domain 3 score: -1.8 bits; conditional E-value: 0.67 DUF3333 77 eklvkqaleaalp...eveerrekrklae.llssgaeyqlrdrvlad 119 +++++ a++ a++ e+ ++ ++++ +ls++ + lr+++ + FUN_001079-T1 353 HYMIE-AMKFAFGqrsLLEDSKNLTDIIQeMLSKKHANLLRAKISPN 398 55553.45555553323345566666666699999999999888766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (613 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 872 (0.0341358); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 5837.57 // Query: FUN_001080-T1 [L=633] Description: FUN_001080 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-154 513.6 0.0 1e-153 513.3 0.0 1.1 1 G_glu_transpept Gamma-glutamyltranspeptidase ------ inclusion threshold ------ 0.019 14.6 0.0 4.3 6.9 0.0 2.5 2 Asparaginase_2 Asparaginase 0.17 11.9 0.4 0.29 11.2 0.4 1.3 1 DUF6346 Family of unknown function (DUF6346) Domain annotation for each model (and alignments): >> G_glu_transpept Gamma-glutamyltranspeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 513.3 0.0 1.2e-157 1e-153 2 512 .] 118 626 .. 117 626 .. 0.96 Alignments for each domain: == domain 1 score: 513.3 bits; conditional E-value: 1.2e-157 G_glu_transpept 2 eiLrkGGnAvDAavAaalclgvvepqssGiGGGgfll..vydaktkkveaidaretAPaaatkdmfekkgdsklsktgglavgVPGevagleea 93 + LrkGG+AvDAa+ ++lc+gv++p+s+GiGGGgf+l v +++++++++id+re+AP aa+kdmf +g++ l++ gglavgVPGe++g+e a FUN_001080-T1 118 DLLRKGGSAVDAAIGTMLCVGVMNPESTGIGGGGFMLsvVPQNDGEAAKVIDFREVAPLAASKDMF--HGNASLASWGGLAVGVPGEIRGYELA 209 68**********************************7436677788889*****************..************************** PP G_glu_transpept 94 hkryGrlpwadllepaiklareGfpvspalaaalaeaeerlkkdpelakiFlpegevlkagellkqpalAktLerlaeeGaeaFYeGelAeklv 187 hk+yG+l+w++l++paik+areGf v++++++ l++ +e++ + el k+ +p+g+ lk+g+++ +palA+tL+++a++Ga+aFY+G +A++lv FUN_001080-T1 210 HKKYGKLKWSELFAPAIKIAREGFSVTEHTERSLKNLKEHVIGT-ELGKVVAPKGKLLKEGDKMSNPALANTLQKIADHGADAFYKGPIADSLV 302 ************************************99996655.4669********************************************* PP G_glu_transpept 188 aelqkngGiltaeDLanYkveveeplsadyrggytvyepppssggivllqiLnilekfdlkslslesaetlhlliEamklayadRsrylgDpdf 281 + ++ +gGilt++DL+ Y++ +e+++++y +gy+v+++p +sgg+vl+ +Lnil++f++++ ++++ t+h +iEamk+a+++Rs l D + FUN_001080-T1 303 KAVRSAGGILTKKDLKIYNALEKEAINSTY-KGYRVITTPLPSGGPVLISMLNILDGFKFSKEDRDKSLTYHYVIEAMKFAFGQRSL-LEDSNN 394 ******************************.99**************************99999999********************.****99 PP G_glu_transpept 282 vkvpeelvenllskeyakeraklIndkaaapsseyykaaeaaeedggTthlsvvDaegnaVSltstinleFGsgvvvpgtGilLnnemddfst. 374 +++ ++++lsk++a+ ++++I++++++p ++y+ + ++ ++gT+h+s++ +g+ ++tst+n +FGsg++++ tGilLnnem dfs+ FUN_001080-T1 395 LTDI---IQEMLSKKHANLLRAKISPNQTFP-LSHYELMVDQAASHGTAHVSAIGPDGDLAAITSTVNGHFGSGIMSK-TGILLNNEMLDFSIp 483 9755...************************.89********************************************.*************** PP G_glu_transpept 375 gvenafgldpspanaiePgkRplssmaPtivlk.dgkvkl..vvGaaGGsriisavlqvlvnvldlglslqeavdaprlhhqllpdelevEe.. 463 gv++ g p+ an+++PgkRpls ++Pt vl+ +++ +l +G++G+ +ii av+ +l+n+l ++ +l+ea+++ r+ l++ ++e+E FUN_001080-T1 484 GVQRVIGAGPPRANFVAPGKRPLSNTVPTAVLHeEKRCWLrtSLGGSGSYQIIPAVAHTLINILSFNFPLSEAIEKGRVSYGLTSGKTEIEVkr 577 *********************************7666666669*******************************************99999987 PP G_glu_transpept 464 ...gfseevlaeLearghkvkevedsssvvaiqavlkengvleaasDprrdg 512 + +e+++ Le+ gh+v++ + v+ +++++a D+rr g FUN_001080-T1 578 fplKKAKELVEVLENIGHNVTNHSGIADVNGLSYF---KEEIVAHGDSRRGG 626 88888899*************99999999888888...79999999999975 PP >> Asparaginase_2 Asparaginase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.0005 4.3 21 52 .. 100 131 .. 80 162 .. 0.82 2 ? 4.9 0.0 0.002 17 126 201 .. 379 456 .. 368 463 .. 0.73 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0005 Asparaginase_2 21 ereeavrkalkeaveegykvLkeggsaldave 52 + ++av + +ke+++ g ++L++ggsa+da + FUN_001080-T1 100 TVHAAVVSDVKECADVGLDLLRKGGSAVDAAI 131 556788999********************976 PP == domain 2 score: 4.9 bits; conditional E-value: 0.002 Asparaginase_2 126 eefarelgleevdpetllteerleelkeekkenkkkkvaksvs...aekekaeeeeaklgTvGvValDkegnlAagTST 201 ++fa + +d+ lt+ +e l +++++ + k++++++ ++ e ++ a++gT v a+ +g lAa TST FUN_001080-T1 379 MKFAFGQRSLLEDS-NNLTDIIQEMLSKKHANLLRAKISPNQTfplSHYELMVDQAASHGTAHVSAIGPDGDLAAITST 456 55665555444444.6677776666666666666666776666664555566777999********************9 PP >> DUF6346 Family of unknown function (DUF6346) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.4 3.4e-05 0.29 3 54 .. 66 116 .. 64 116 .. 0.89 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 3.4e-05 DUF6346 3 srlrsavvllavlvvslllfgtvvtltrgtGrdyaeaertgtAtVeeCerhG 54 +r+rs + ++++v ++l++++++ + tG+dy+ ++ + V+eC+++G FUN_001080-T1 66 RRTRSRYIRVIIIVSTILIINVALVVGILTGSDYT-VHAAVVSDVKECADVG 116 56778888999**********************86.6778899******998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (633 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 899 (0.0351928); expected 510.9 (0.02) Passed bias filter: 766 (0.0299863); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6078.34 // Query: FUN_001081-T1 [L=488] Description: FUN_001081 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-75 254.6 0.0 2e-75 254.1 0.0 1.2 1 Pkinase Protein kinase domain 4.9e-51 172.7 0.1 9e-51 171.9 0.1 1.4 1 CaMKII_AD Calcium/calmodulin dependent protein kinase I 2.4e-33 116.0 0.0 3.2e-33 115.6 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.3e-07 32.5 0.0 2.8e-07 31.5 0.0 1.6 1 DUF4440 Domain of unknown function (DUF4440) 0.00023 21.9 0.0 0.00044 21.0 0.0 1.5 1 SnoaL_3 SnoaL-like domain 0.0024 17.2 0.0 0.0041 16.4 0.0 1.3 1 Pkinase_fungal Fungal protein kinase ------ inclusion threshold ------ 0.01 16.1 0.1 5.9 7.1 0.0 2.2 2 APH Phosphotransferase enzyme family 0.011 15.6 0.3 0.011 15.6 0.3 2.5 3 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.025 14.2 0.0 0.042 13.5 0.0 1.4 1 ABC1 ABC1 atypical kinase-like domain Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 254.1 0.0 7.1e-79 2e-75 1 262 [] 17 275 .. 17 275 .. 0.96 Alignments for each domain: == domain 1 score: 254.1 bits; conditional E-value: 7.1e-79 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgals 96 ye +e+lG+G+f+ V ++v+k+t+ ++A K+i+++k ++++ +k+ rE +i + lkh nivrl+ +++e+ + ylv+++v+ggelf+ + ++ +s FUN_001081-T1 17 YELKEELGKGAFSIVRRCVHKDTKVEYAAKIINTKKLSSRDLQKLEREARICRLLKHANIVRLHASISEEGYHYLVFDLVTGGELFEDIVAREYYS 112 8999*************************************9****************************************************** PP Pkinase 97 eeeakkilkqilegleylHsegvvHrDlKpeNiLidekge...lKitDFGlakelesssk.ltsfvgtseYmAPEvlkskkygkkvDvWslGvily 188 e++a++ ++qile+++++H+++vvHrDlKpeN+L+ +k++ +K++DFGla e++ +++ f gt+ Y++PEvlk+++yg++vD+W++Gvily FUN_001081-T1 113 EADASHCIQQILESVHHCHHNNVVHRDLKPENLLLASKEKgaaVKLADFGLAIEVDGDKHgWYGFAGTPGYLSPEVLKKEPYGRPVDLWACGVILY 208 ************************************777788***************999999********************************* PP Pkinase 189 elltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 ll g ppf++e++++ ++++ ++ +pe++++ +eak+l++ ll++d+++R+ta+e+l+hpw+ FUN_001081-T1 209 ILLVGYPPFWDEDQHKLYSQIKAG-------AYDYPSPEWDTVTDEAKELINTLLSVDQSRRITASEALKHPWI 275 **********66666655555555.......78999*************************************7 PP >> CaMKII_AD Calcium/calmodulin dependent protein kinase II association domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 171.9 0.1 3.2e-54 9e-51 1 127 [. 356 482 .. 356 483 .. 0.99 Alignments for each domain: == domain 1 score: 171.9 bits; conditional E-value: 3.2e-54 CaMKII_AD 1 ekqeiiklletlleaisegdfetytklcdpeltvfepevlgnlveglefhrfyfekllakrkkavrttilnkrvrllgddsAviayvrlltlldkn 96 ++q ii+l+++l+ +i++gdfety kl+d+ lt+fepe+ gnlveglefhrfyf+++++kr+ +++ttil ++v+++gd++A+i yvrl +++ FUN_001081-T1 356 REQRIIQLTQKLITSITTGDFETYCKLVDQRLTAFEPEAKGNLVEGLEFHRFYFDNVYTKRTSPINTTILSPHVHMMGDEAACICYVRLQQFITST 451 5899******************************************************************************************** PP CaMKII_AD 97 GkkhtrqseetrVwekrdgkWkivhvHrSaa 127 G + t+qseetrVw+k+ g+W++vh+HrS + FUN_001081-T1 452 GVPLTKQSEETRVWHKKSGRWVNVHFHRSNM 482 *****************************87 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 115.6 0.0 1.1e-36 3.2e-33 2 253 .. 18 268 .. 17 272 .. 0.88 Alignments for each domain: == domain 1 score: 115.6 bits; conditional E-value: 1.1e-36 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtl.keeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk 95 elke+lG+Gaf+ V ++ k ++k++ a K++ +++ s+++ +++ +ea++ + l+h niv+l++ ++ee+ +++v+++v+gG+L e + + FUN_001081-T1 18 ELKEELGKGAFSIVRRCVHK----DTKVEYAAKIInTKKLSSRDLQKLEREARICRLLKHANIVRLHASISEEGYHYLVFDLVTGGELFEDIVA- 107 6899**************99....99999*****94456677779*******************************************999999. PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse...kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDv 187 +e +s + ++++qi + +++ +++++vHrdl N L+++ vk++DfGLa +v d +++ + +++pE+lk++ + D FUN_001081-T1 108 REYYSEADASHCIQQILESVHHCHHNNVVHRDLKPENLLLASkekGAAVKLADFGLAIEV--DGDKHGWYGFAGTPGYLSPEVLKKEPYGRPVDL 200 6899999*********************************98444559************..444455556667779****************** PP PK_Tyr_Ser-Thr 188 WsfGvllwEiftlgeepykglkneevlelleeg.er..leqpencpeelyelmkeCweedpeeRptfke 253 W+ Gv+l+ ++ g p+ + +++++++++++g + ++ +++++e +el+++ + d+++R t +e FUN_001081-T1 201 WACGVILYILLV-GYPPFWDEDQHKLYSQIKAGaYDypSPEWDTVTDEAKELINTLLSVDQSRRITASE 268 ********6665.*****************87633411555578999*****************99876 PP >> DUF4440 Domain of unknown function (DUF4440) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.5 0.0 9.7e-11 2.8e-07 1 106 [. 360 473 .. 360 474 .. 0.91 Alignments for each domain: == domain 1 score: 31.5 bits; conditional E-value: 9.7e-11 DUF4440 1 iralerallealvagdaealaallapdfvlvgps..gpvldkaellealea....ggldyssieltdvevrvlgdvAvvtgrstvea..rgdgepv 88 i +l ++l +++++gd+e++++l + ++ + p g ++ + e++ ++++ +++++ ++ + +v+++gd A +++++++ + g p+ FUN_001081-T1 360 IIQLTQKLITSITTGDFETYCKLVDQRLTAFEPEakGNLVEGLEFHRFYFDnvytKRTSPINTTILSPHVHMMGDEAACICYVRLQQfiTSTGVPL 455 789999*************************99888**************96666666667778899******************99555589*** PP DUF4440 89 tvrgrftsvwkkegggWk 106 t+ + t+vw k+ g+W FUN_001081-T1 456 TKQSEETRVWHKKSGRWV 473 *****************6 PP >> SnoaL_3 SnoaL-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 1.5e-07 0.00044 2 118 .. 361 481 .. 360 484 .. 0.79 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1.5e-07 SnoaL_3 2 ealndafyeaaaegdfdalfalwsddvscigtdasel.lrgreevrrs.wrqifaq.tqglqfelrelrvteagdvawvtellni..kaeddgeea 92 +l +++++ +++gdf+++ +l + + ++ + a+ + ++g e+ r+ +++ + t +++ ++ +++v+ gd a ++ ++ +++ g + FUN_001081-T1 361 IQLTQKLITSITTGDFETYCKLVDQRLTAFEPEAKGNlVEGL-EFHRFyFDNVYTKrTSPINTTILSPHVHMMGDEAACICYVRLqqFITSTGVPL 455 688999*************************98877725555.5555505555554388***********98887777666666632334777888 PP SnoaL_3 93 egelrlTnvlrrtdggWkivhhhlSv 118 + + T v + +g+W vh h S FUN_001081-T1 456 TKQSEETRVWHKKSGRWVNVHFHRSN 481 999999*****************994 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 1.5e-06 0.0041 301 369 .. 129 193 .. 106 212 .. 0.79 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 1.5e-06 Pkinase_fungal 301 sLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielsessasgarertGTleFmaiellkgee 369 + + +++++HrD +N+++ ke++ L D+ laie++ ++g GT +++ e+lk+e FUN_001081-T1 129 HCH-HNNVVHRDLKPENLLLA--SKEKGAAVKLADFGLAIEVDG-DKHGWYGFAGTPGYLSPEVLKKEP 193 445.89***************..7788999*************6.555778999*******99999765 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.0021 5.9 31 85 .. 51 103 .. 31 125 .. 0.73 2 ? 6.9 0.0 0.0024 6.7 170 187 .. 135 152 .. 111 164 .. 0.79 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0021 APH 31 g....eaaeelerelallrhLaaagvvpvPrvlagetdaellglpfllmeylpGedler 85 + ++lere++++r+L+ a + r++a + +++g+++l++ + G +l + FUN_001081-T1 51 KklssRDLQKLEREARICRLLKHANI---VRLHA---SISEEGYHYLVFDLVTGGELFE 103 4444578999**************77...69999...6677777778877777776655 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0024 APH 170 lvHgDlhpgNllvd..dggr 187 +vH+Dl+p Nll+ + + FUN_001081-T1 135 VVHRDLKPENLLLAskE--K 152 89**********99543..3 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.1 0.24 6.9e+02 170 203 .. 45 79 .. 41 83 .. 0.71 2 ? 15.6 0.3 4e-06 0.011 104 166 .. 101 161 .. 82 167 .. 0.85 3 ? -3.4 0.1 2.6 7.3e+03 16 46 .. 261 296 .. 257 304 .. 0.63 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 0.24 Kdo 170 rlrlrakrwrekdLarLkrsfl.kielteadweal 203 ++++ k+ +++dL++L+r + + l +a++ +l FUN_001081-T1 45 AKIINTKKLSSRDLQKLEREARiCRLLKHANIVRL 79 5667789999*********8765444555555555 PP == domain 2 score: 15.6 bits; conditional E-value: 4e-06 Kdo 104 dLedllaqwaelaeelrrallkavgrlirklhragvqHgdlyakhillqtekeeeakasliDl 166 ed++a+ + ++e+ ++++ + +++ h+ +v H+dl + ++ll ++ ++a + l D+ FUN_001081-T1 101 LFEDIVAR-EYYSEADASHCIQQILESVHHCHHNNVVHRDLKPENLLLASKE-KGAAVKLADF 161 56777776.44999999********************************997.8888999888 PP == domain 3 score: -3.4 bits; conditional E-value: 2.6 Kdo 16 grrtgwfevaev.....vesalrkyyrggmtgklsk 46 rr++++e+ ++ e++ +k +r +++ l k FUN_001081-T1 261 SRRITASEALKHpwivnRERVASKVHRQETLDGLKK 296 577777777776666555666777777766666555 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 1.5e-05 0.042 145 222 .. 90 171 .. 60 176 .. 0.73 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.5e-05 ABC1 145 vLtmeyvdGikidd.leale.eagidrkeiaeklvelfleqifedgffhaDphpGNllvrkdg...elvllDfGlmgeldekf 222 +L+ ++v G ++ + + a e + d+++ +++++e++ ++ +++++h D+ p Nll+ +++ + l DfGl e+d ++ FUN_001081-T1 90 YLVFDLVTGGELFEdIVAREyYSEADASHCIQQILESV-HHCHHNNVVHRDLKPENLLLASKEkgaAVKLADFGLAIEVDGDK 171 57777777776633022111122444555555555543.56778999***********99888788999*******9998665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (488 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1042 (0.0407908); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.34u 0.43s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 4755.45 // Query: FUN_001082-T1 [L=335] Description: FUN_001082 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-30 107.2 0.5 2.5e-30 106.2 0.1 1.7 2 Band_7 SPFH domain / Band 7 family ------ inclusion threshold ------ 0.03 15.0 0.2 0.069 13.8 0.2 1.6 1 Catalase-rel Catalase-related immune-responsive Domain annotation for each model (and alignments): >> Band_7 SPFH domain / Band 7 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.2 0.1 2e-34 2.5e-30 2 177 .] 24 206 .. 23 217 .. 0.91 2 ? -1.4 0.1 0.22 2.8e+03 140 166 .. 220 246 .. 207 270 .. 0.63 Alignments for each domain: == domain 1 score: 106.2 bits; conditional E-value: 2e-34 Band_7 2 ivppgevgvvirfGklsr.vlgpGlhfviPfiqsvltvdvrvqeievkvqtvltkDgvpvtvdvsvvyrv.npddpaklvaevkgsddleelirev 95 ++++g+vgv++r G+l + gpG+h +iPf++s++ v ++ q+ evk++++ t+ gv +++d + v+++ +++ + +v+++ + d+ ++li ++ FUN_001082-T1 24 KIDEGHVGVYYRGGALLSsTSGPGYHNMIPFLTSFRSVQTTLQTDEVKNVPCGTSGGVVIYFDRIEVVNIlQASSVFDIVRNY-TADYDKALIFNK 118 79**********8888877***************************************************9999999999999.************ PP Band_7 96 iesalreiiakytleellsn.reelaeevkdalnee..lakygveiidvqirdidlppeiaea...iekkqaaeqeaeaeiaeaeaea 177 i+++l+++++ +tl+e++ + ++++e+++ al+++ l + g+ ++ v+++++++p++i+++ +e ++++ +a++++++ e+ea FUN_001082-T1 119 IHHELNQFCSAHTLQEVYIDhFDQIDENLRTALQQDllLMAPGLRVQAVRVTKPKIPESIRRNyesMEGEKTKLLIAQQKQKVVEKEA 206 ******************9978**************999**********************996665555555555566666666665 PP == domain 2 score: -1.4 bits; conditional E-value: 0.22 Band_7 140 dvqirdidlppeiaeaiekkqaaeqea 166 +q+ +i++ ++i e k+ +e+e FUN_001082-T1 220 AAQVSKIQFGQKIMEKESLKKMSEIED 246 567888888888877755555555555 PP >> Catalase-rel Catalase-related immune-responsive # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.2 5.4e-06 0.069 20 63 .. 109 153 .. 101 155 .. 0.87 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 5.4e-06 Catalase-rel 20 eeererlvkniafel.skvkdeeiqermlehlakvDpdlgqrVae 63 + +++ +++ i el + ++ + qe +++h+ ++D++l +++++ FUN_001082-T1 109 DYDKALIFNKIHHELnQFCSAHTLQEVYIDHFDQIDENLRTALQQ 153 778999*********666********************9887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (335 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2447 (0.0957917); expected 510.9 (0.02) Passed bias filter: 859 (0.0336269); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3240.26 // Query: FUN_001083-T1 [L=372] Description: FUN_001083 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-45 154.9 17.8 3.6e-45 154.9 17.8 1.3 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.8e-09 37.9 15.4 2.4e-09 37.4 15.4 1.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 1.1e-05 25.4 15.4 5.7e-05 23.0 15.4 1.8 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.0031 16.9 13.3 0.0031 16.9 13.3 2.1 2 Transp_cyt_pur Permease for cytosine/purines, uracil, thiami ------ inclusion threshold ------ 2.3 8.3 5.6 22 5.1 0.0 2.7 3 Orbi_NS3 Orbivirus NS3 7.6 7.1 12.7 0.59 10.7 0.8 3.0 2 DUF4083 Domain of unknown function (DUF4083) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 2 8.5e+03 15 28 .. 31 44 .. 15 44 .. 0.77 2 ! 154.9 17.8 8.5e-49 3.6e-45 1 260 [] 46 311 .. 46 311 .. 0.89 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 2 xxxxxxxxxxxxxx RF 7tm_1 15 lrtptnifllnLav 28 l+t+ ++f++ Lav FUN_001083-T1 31 LKTVVYLFIVLLAV 44 56777777777765 PP == domain 2 score: 154.9 bits; conditional E-value: 8.5e-49 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.....legdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkpl 91 gN +Vi +++++ ++++tn++++n+av Dl ++++++ ++v+ + + +d +fg++ Ck+v++ + +++ +si++l +++++RY aI+ pl FUN_001083-T1 46 GNAFVIRTVYTRSGMKSATNYLIVNMAVGDLFMAIFNMIPTVVTMFrgnhsWASDGPFGKISCKMVIFSQATSMACSIITLSVLAFERYFAIISPL 141 8**********************************77777776655311114556689************************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 92 kykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlrksak 185 + + + r++ l++++Wv +++ + p+l+ +++ + k++ C+ d+ ++++++++yt++++vl + +pllvi+++y i+ t+++++ FUN_001083-T1 142 SK--VASTARTRWLVAAIWVSSFASASPMLYAAKVRLY---KGVPYCFEDWAPafDTKKAQAIYTIVAFVLLYAIPLLVIFILYLIIIVTVWERHI 232 *9..7899999999*****************9988777...99********99667777************************************9 PP xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 keks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsl.lkeceseklvetallitlllayvnsclNPiiY 260 ++ + + ++++++ +lk+l++vvv+f+lcw+P+++ l+l+ + + + ++ ++ + ll++++ns++N iY FUN_001083-T1 233 PGNTtlaNVRLHNKAKKNVLKMLITVVVAFALCWFPIHLNLFLKDFtDLFPDPCGIPVWLQTTGLLFGHANSAVNCCIY 311 99986664555667777*****************************655567777888888999***********9999 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.4 15.4 5.7e-13 2.4e-09 2 255 .. 41 324 .. 40 326 .. 0.75 Alignments for each domain: == domain 1 score: 37.4 bits; conditional E-value: 5.7e-13 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgel.vfvvllltgtql.kreeCFllii.....vyvfgltaqsvllL.vigiDllia 89 ++ ++GN +i +++++ ++s +++Li+ ++ dl++ ++++ ++vv +++g+++ ++ F i+ + +a s++ L v+++ + +a FUN_001083-T1 41 LLAVFGNAFVIRTVYTRSGMKSATNYLIVNMAVGDLFMAIFNMiPTVVTMFRGNHSwASDGPFGKISckmviFSQATSMACSIITLsVLAFERYFA 136 5789*********************************9887651677799987765244445544441100033333445566666256899**** PP 7TM_GPCR_Srsx 90 vkfPirYrllskek.YllillifpvlyssiilvlgflqrddetiivCappla..l.agkaseiftlssliinviv..llvylvliiilkkkkek.. 177 + P+ + ++ +l++ + + s++ +++ +r ++ +++C a + ++ka i+t+ +++ ++ l++++ ii+ + e+ FUN_001083-T1 137 IISPLSKVASTARTrWLVAAIWVSSFASASPMLYAAKVRLYKGVPYCFEDWApaFdTKKAQAIYTIVAFVLLYAIplLVIFILYLIIIVTVWERhi 232 ****9876655555599999999999999******************8655411314678889988877665443114444444444444444457 PP 7TM_GPCR_Srsx 178 ...........kkssskkvlkslkvtvvififgWftsti...lntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafre 255 +++ k+vlk l ++vv f ++Wf + l++++ +++ + +q+ ++ +++ n ++++ s+++r+ f++ FUN_001083-T1 233 pgnttlanvrlHNKAKKNVLKMLITVVVAFALCWFPIHLnlfLKDFTDLFPDPCGIPVWLQTTGLLFGHANSAVNCCIYVIFSQDFRNGFKD 324 899999999999**********************96554111566667777778889999999999999*******************9986 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 15.4 1.3e-08 5.7e-05 5 316 .. 38 326 .. 34 328 .. 0.77 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 1.3e-08 7TM_GPCR_Srw 5 ilsivgviinifHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppd.sylkvlldlileslkdvsrrcstwlgvlm 99 ++ +++v+ n f + +s ++s++n l++ +a+ D++ ++++++ +++ ++ ++ + +d ++ k+ +++ +++ + +s cs+ ++ FUN_001083-T1 38 FIVLLAVFGNAFVIRTVYTRSGMKSATNYLIVNMAVGDLFMAIFNMIPTVVTMFRG---NHSWASDgPFGKISCKM-VIFSQATSMACSIITLSVL 129 67778888888888666666777899**************9999999998555554...55555551666666555.9999*************** PP 7TM_GPCR_Srw 100 AliRtlvvknplsnkiqklskpkfgllii.livlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifll 194 A+ R++ + pls+ ++ ++++ +l+ ++v+ + ++ +l+ +++++ + + C e+ ++ + ++ + i+++ FUN_001083-T1 130 AFERYFAIISPLSKVAS---TARTRWLVAaIWVSSFASASPMLYAAKVRLY--KGV----PYCF---ED-WAPAFDTKK----------AQAIYTI 202 ************99764...5555555441344445555556666666666..323....3596...22.334444322..........3447777 PP 7TM_GPCR_Srw 195 idgilskiipsillpiltilLiieLrkakksrkklsksk..kneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifsl 288 + +l+ ip +++ il ++ i+ ++ +++ + +n+ +++ k+ + + + f + +p+ + ++k + + ++ i l+ l FUN_001083-T1 203 VAFVLLYAIPLLVIFILYLIIIVTVWERHIPGNTTLANVrlHNKAKKNVLKMLITVVVAFALCWFPIHLNLFLKDFTDLFPDPCGIPVWLQTTGLL 298 77789999*****************9999887777733335789999***************************9988888888888888888889 PP 7TM_GPCR_Srw 289 lltinsisHflicllmSsqYRktvkklf 316 + +ns++ + i++++S R+ +k+++ FUN_001083-T1 299 FGHANSAVNCCIYVIFSQDFRNGFKDFI 326 999*******************999876 PP >> Transp_cyt_pur Permease for cytosine/purines, uracil, thiamine, allantoin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 3.7 0.032 1.4e+02 277 342 .. 29 92 .. 20 99 .. 0.78 2 ! 16.9 13.3 7.2e-07 0.0031 120 312 .. 92 279 .. 83 291 .. 0.85 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.032 Transp_cyt_pur 277 kfdptagvllililvalaqlgvnisanlvsagldlaallPkkinikrgsliaavialvivpwkLls 342 ++++t+++l+i++l+ + + v+ + + s + +++ l +n+++g l++a+ ++ +++++ FUN_001083-T1 29 EWLKTVVYLFIVLLAVFGNAFVIRTVYTRSGMKSATNYLI--VNMAVGDLFMAIFNMIPTVVTMFR 92 7899988888888877777777777777766666666666..************999999998875 PP == domain 2 score: 16.9 bits; conditional E-value: 7.2e-07 Transp_cyt_pur 120 fgkwleiggailgtsltelvtffifwvvslvivllgvskirkffviaallipvaafgfliWaavkaegGpvldkavklgkse.lflsavagvvag 213 g+ +++ ++ g + +v f + i+ l+v +++++f+i+++l +va+ + W+++++ +++ ++++ l +++ + ++v + FUN_001083-T1 92 RGNHSWASDGPFGKISCKMVIFSQATSMACSIITLSVLAFERYFAIISPLSKVASTARTRWLVAAIWVSSFASASPMLYAAKvRLYKGVPYCFED 186 455677777677777788888888888999999**************************************9988887766679*********** PP Transp_cyt_pur 214 fatlilnapDFtryakt.akssvkiqlvavpllftlllligilvaaaakaayganawspldilakfdptagvllililvalaqlgvnisanlvsa 307 +a++ t+ a+ ++ +++ l+a+pll++ +l + i+v++ ++ g ++ + + + +k+ +++ +li ++va+a ++ i +nl + FUN_001083-T1 187 WAPAFD-----TKKAQAiYTIVAFVLLYAIPLLVIFILYLIIIVTVWERHIPGNTTLANVRLHNKAKKNVLKMLITVVVAFALCWFPIHLNLFL- 275 **9887.....554443156667778999**********************************************************9999854. PP Transp_cyt_pur 308 gldla 312 d++ FUN_001083-T1 276 -KDFT 279 .4444 PP >> Orbi_NS3 Orbivirus NS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 1.0 0.01 42 74 143 .. 62 135 .. 47 150 .. 0.82 2 ? 2.4 1.5 0.033 1.4e+02 74 138 .. 196 262 .. 192 264 .. 0.62 3 ? 5.1 0.0 0.0051 22 71 137 .. 242 311 .. 227 319 .. 0.80 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.01 Orbi_NS3 74 lkrkrlllklv..elilavlalltslvmlvkelsetvekns..evpawlkslsavvsvinllatvvllvlarie 143 + +l+++++ l++a++ ++ +v++ +++ ++ +++ + +s+++s+ ++t +l+++r+ FUN_001083-T1 62 SATNYLIVNMAvgDLFMAIFNMIPTVVTMFRGNHSWASDGPfgKISCKMVIFSQATSMACSIITLSVLAFERYF 135 456677888887889**********9999999999998733568999999999999999999999999999875 PP == domain 2 score: 2.4 bits; conditional E-value: 0.033 Orbi_NS3 74 lkrkrlllklvelil..avlalltslvmlvkelsetveknsevpawlkslsavvsvinllatvvllv 138 + ++++ +v+l + ++ ++ l+++v+ ++ +++ n+++ + +a +v+++l+tvv+ + FUN_001083-T1 196 AQAIYTIVAFVLLYAipLLVIFILYLIIIVTVWERHIPGNTTLANVRLHNKAKKNVLKMLITVVVAF 262 4555566666543331033344444559999999***998876666446677778888888887655 PP == domain 3 score: 5.1 bits; conditional E-value: 0.0051 Orbi_NS3 71 lrklkrkrlllklvelilavlalltslv...mlvkelsetveknsevpawlkslsavvsvinllatvvll 137 + k k+ +lk++ ++ ++al ++ + k++++ +++ +p wl++ +++ n ++ ++ FUN_001083-T1 242 RLHNKAKKNVLKMLITVVVAFALCWFPIhlnLFLKDFTDLFPDPCGIPVWLQTTGLLFGHANSAVNCCIY 311 556788999999999999999**99998666778888888888559*****9888888877777665554 PP >> DUF4083 Domain of unknown function (DUF4083) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.8 0.00014 0.59 5 35 .. 30 61 .. 28 87 .. 0.89 2 ? -0.3 5.2 0.36 1.5e+03 6 30 .. 199 223 .. 196 233 .. 0.75 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00014 DUF4083 5 llyliivlvLilllvfsftlfiRrvvsrsa.k 35 +l +++ l ++ll vf+ ++iR v rs k FUN_001083-T1 30 WLKTVVYLFIVLLAVFGNAFVIRTVYTRSGmK 61 7788889999******************9743 PP == domain 2 score: -0.3 bits; conditional E-value: 0.36 DUF4083 6 lyliivlvLilllvfsftlfiRrvv 30 +y+i+ +vL+ ++ +++++ ++ FUN_001083-T1 199 IYTIVAFVLLYAIPLLVIFILYLII 223 8999999999888777777765544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (372 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1207 (0.04725); expected 510.9 (0.02) Passed bias filter: 475 (0.0185946); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3579.33 // Query: FUN_001084-T1 [L=365] Description: FUN_001084 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-29 102.4 15.5 5.9e-29 101.8 15.5 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.00019 21.3 13.1 0.0013 18.6 13.1 2.0 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 101.8 15.5 4.6e-33 5.9e-29 50 260 .] 99 307 .. 85 307 .. 0.88 Alignments for each domain: == domain 1 score: 101.8 bits; conditional E-value: 4.6e-33 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 50 dwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpee 145 + g++lCkl+++l ++++ a il+l++i+ DR++aI+ p+++ + r a+ li++ Wv+ +l s ++l++ ++ + Cl +++ FUN_001084-T1 99 SGLAGTILCKLQGFLALCTVNAAILTLAVIAADRFIAIFFPMRR--AISSRTAIWLIAASWVVPALPSSLFLYVYRLFDF---DGTLYCLEQWSPA 189 566799**************************************..7899***********************9999999...89********996 PP xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 146 est.wevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkecesekl 237 + +y ++ ++l++ lpl+ i+++y i+ ++++++ + +++ + ++++ +lk+l++ v++f+l+wlP il++++ + + ++ FUN_001084-T1 190 IPLyINTIYSTVDIILFYALPLVEIIIFYGAIIYKIWMRKIPGQAtsvNQQLELKAKKSVLKVLITAVLTFALFWLPTKILTVIALI-GDVPCIMR 284 65557778888888888888*******************9999886666777778888****************************9.55566666 PP xxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 238 vetallitlllayvnsclNPiiY 260 ++ + + l+la++n+++NP+iY FUN_001084-T1 285 SPLIRFVNLFLACMNCAINPLIY 307 666678999************** PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 13.1 1e-07 0.0013 95 318 .. 124 324 .. 109 325 .. 0.78 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 1e-07 7TM_GPCR_Srw 95 lgvlmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllk 190 ++A R++ + +p+++ i+ +++++++i+ ++ +l s+l+++ y++ + + + + C e + + + + +++ FUN_001084-T1 124 TLAVIAADRFIAIFFPMRRAIS----SRTAIWLIAASWVVPALPSSLFLYVYRLFDFDGTLY----CL---E-----QWSPAIPLY-------INT 196 55679999**********9986....999*************************98887777....96...2.....222222222.......467 PP 7TM_GPCR_Srw 191 ifllidgilskiipsillpiltilLiieLrkakksrkklskskkneksdkttkLVlfmTi..sffiaelplGiiyivkfifskssgirsileelev 284 i+ ++d il+ +p + ++i+ + i++++ k + +s +++ e + k++ L +++T +f + lp i+++++ + + + ++ + + + FUN_001084-T1 197 IYSTVDIILFYALPLVEIIIFYGAIIYKIWMRKIPGQATSVNQQLELKAKKSVLKVLITAvlTFALFWLPTKILTVIAL-IGDVP-CIMRSPLIRF 290 89999999*********************99999999999666556666666666666651144455566666777744.55555.4555666777 PP 7TM_GPCR_Srw 285 ifsllltinsisHflicllmSsqYRktvkklfgc 318 + +l ++n ++ li+l++S YR+ +k f c FUN_001084-T1 291 VNLFLACMNCAINPLIYLIFSRDYRNGFKASFHC 324 777899***********************99998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (365 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 819 (0.0320611); expected 510.9 (0.02) Passed bias filter: 389 (0.015228); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3578.16 // Query: FUN_001084-T2 [L=290] Description: FUN_001084 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-29 102.6 15.0 4.5e-29 102.2 15.0 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 8.2e-05 22.5 12.7 0.00052 19.9 12.7 1.9 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00029 21.0 9.7 0.00043 20.4 9.7 1.3 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 0.00088 19.0 12.4 0.0011 18.7 12.4 1.2 1 7TM_GPCR_Srd Serpentine type 7TM GPCR chemoreceptor Srd Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.2 15.0 7e-33 4.5e-29 53 260 .] 27 232 .. 21 232 .. 0.90 Alignments for each domain: == domain 1 score: 102.2 bits; conditional E-value: 7e-33 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 53 fgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeest 148 g++lCkl+++l ++++ a il+l++i+ DR++aI+ p+++ + r a+ li++ Wv+ +l s ++l++ ++ + Cl +++ FUN_001084-T2 27 AGTILCKLQGFLALCTVNAAILTLAVIAADRFIAIFFPMRR--AISSRTAIWLIAASWVVPALPSSLFLYVYRLFDF---DGTLYCLEQWSPAIPL 117 6899*************************************..7899***********************9999999...89********996655 PP .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 149 .wevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvet 240 + +y ++ ++l++ lpl+ i+++y i+ ++++++ + +++ + ++++ +lk+l++ v++f+l+wlP il++++ + + ++ ++ FUN_001084-T2 118 yINTIYSTVDIILFYALPLVEIIIFYGAIIYKIWMRKIPGQAtsvNQQLELKAKKSVLKVLITAVLTFALFWLPTKILTVIALI-GDVPCIMRSPL 212 57778888888888888*******************9999886666777778888****************************9.55566666666 PP xxxxxxxxxxxxxxxxxxxx RF 7tm_1 241 allitlllayvnsclNPiiY 260 + + l+la++n+++NP+iY FUN_001084-T2 213 IRFVNLFLACMNCAINPLIY 232 678999************** PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 12.7 8.1e-08 0.00052 95 318 .. 49 249 .. 37 250 .. 0.78 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 8.1e-08 7TM_GPCR_Srw 95 lgvlmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllk 190 ++A R++ + +p+++ i+ +++++++i+ ++ +l s+l+++ y++ + + + + C e + + + + +++ FUN_001084-T2 49 TLAVIAADRFIAIFFPMRRAIS----SRTAIWLIAASWVVPALPSSLFLYVYRLFDFDGTLY----CL---E-----QWSPAIPLY-------INT 121 55679999**********9986....99**************************98887777....96...2.....222222222.......467 PP 7TM_GPCR_Srw 191 ifllidgilskiipsillpiltilLiieLrkakksrkklskskkneksdkttkLVlfmTi..sffiaelplGiiyivkfifskssgirsileelev 284 i+ ++d il+ +p + ++i+ + i++++ k + +s +++ e + k++ L +++T +f + lp i+++++ + + + ++ + + + FUN_001084-T2 122 IYSTVDIILFYALPLVEIIIFYGAIIYKIWMRKIPGQATSVNQQLELKAKKSVLKVLITAvlTFALFWLPTKILTVIAL-IGDVP-CIMRSPLIRF 215 89999999*********************99999999999666556666666666666651144455566666777744.55555.4555666777 PP 7TM_GPCR_Srw 285 ifsllltinsisHflicllmSsqYRktvkklfgc 318 + +l ++n ++ li+l++S YR+ +k f c FUN_001084-T2 216 VNLFLACMNCAINPLIYLIFSRDYRNGFKASFHC 249 777899***********************99998 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 9.7 6.8e-08 0.00043 69 229 .. 34 197 .. 27 234 .. 0.63 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 6.8e-08 7TM_GPCR_Srx 69 liglialglYeisplsqllialNRfcavffplkyekifsiknTkiiiviiwivslifit.vlylpegCkllynpetltwsfeetecc...ktiswy 160 l g++al + +++l+ +ia +Rf+a+ffp++ + s + ++++i+++w+v ++ + +ly++ + ++ + + +++ + +ti FUN_001084-T2 34 LQGFLALCTVNAAILTLAVIAADRFIAIFFPMR--RAISSRTAIWLIAASWVVPALPSSlFLYVYR--LFDFDGTLYCLEQWSPAIPlyiNTIYST 125 5678888999999*******************6..5889999************999551555444..6666666665444333333000333333 PP 7TM_GPCR_Srx 161 ld.fllililviitlvlnlltaiklilskkkskstssees..krrrkreinffkQsvlQdllflidlvnyfl 229 +d +l++++ ++ ++++ ++++k+ ++k ++ts +++ + +k ++ ++ +vl +lf + + ++ FUN_001084-T2 126 VDiILFYALPLVEIIIFYGAIIYKIWMRKIPGQATSVNQQleLKAKKSVLKVLITAVLTFALFWLPTKILTV 197 332444444455556666666666666666665544444311344444455556555555555555555555 PP >> 7TM_GPCR_Srd Serpentine type 7TM GPCR chemoreceptor Srd # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 12.4 1.8e-07 0.0011 117 291 .. 72 244 .. 26 245 .. 0.74 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 1.8e-07 7TM_GPCR_Srd 117 kakklillllllyipslsqlivillsktdaleveaetkeehpnynleeysvtGfsdlkslpaliaililtipvvpipiiililrkkilkllks.ns 211 ++ +++ +++++ s l++++ d++ +++ p + l +++ ++d+ + +a+ ++ i++++ ii+ i+ +ki + +s n+ FUN_001084-T2 72 RTAIWLIAASWVVPALPSSLFLYVYRLFDFDGTLYCLEQWSPAIPLYINTIYSTVDI---ILFYALPLVEIIIFYGAIIYKIWMRKIPGQATSvNQ 164 455677777777777778899999999999999999999999998876666665555...55588899*************************555 PP 7TM_GPCR_Srd 212 snmssetkaqhkqLikgLtiQallPlifyiPivtlyllsqltgtellileylifvllalpplldPlitlyfvtPYRkail 291 + +++k+ k Li ++ al l + i +v+ + + ++++ ++ ++l+++ + ++Pli+l+f + YR+ ++ FUN_001084-T2 165 QLELKAKKSVLKVLITAVLTFALFWLPTKILTVIALIGDVPCIMRSPLIRFVNLFLACMNCAINPLIYLIFSRDYRNGFK 244 444456666677777765544444444444336666666667899*******************************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (290 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 938 (0.0367195); expected 510.9 (0.02) Passed bias filter: 447 (0.0174985); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2893.61 // Query: FUN_001085-T1 [L=512] Description: FUN_001085 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-66 223.2 0.8 6e-66 222.8 0.8 1.2 1 Spond_N Spondin_N 9.8e-28 96.7 32.1 5.4e-16 59.1 11.0 3.2 3 TSP1_spondin Spondin-like TSP1 domain 9.5e-14 51.8 31.2 9.6e-09 35.8 9.3 3.9 3 TSP_1 Thrombospondin type 1 domain ------ inclusion threshold ------ 0.28 12.0 28.5 0.069 13.9 10.1 4.5 4 TSP1_CCN CCN3 Nov like TSP1 domain 0.3 11.2 0.0 13 6.0 0.0 2.3 2 HTH_CLF_N Histone-lysine N-methyltransferase CLF, N-termi 9.2 7.1 36.9 0.33 11.8 10.4 4.7 4 TSP1_ADAMTS Thrombospondin type 1 domain Domain annotation for each model (and alignments): >> Spond_N Spondin_N # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 222.8 0.8 1.4e-69 6e-66 1 188 [. 98 282 .. 98 289 .. 0.97 Alignments for each domain: == domain 1 score: 222.8 bits; conditional E-value: 1.4e-69 Spond_N 1 akYeltfeglWsretfpkdyPswrtqwskligasHsseyrlweygeiaseglkelaekgkakkleeelkeaeksekvrtiikakglspnvegktsa 96 a+Y++tf g+W+r+t+p+++P +++ws+ligasHs++y lw+yg +as+g+ +++e+g+ +kl +e+k+ + +++++iik++ l + g+ sa FUN_001085-T1 98 ATYHITFIGKWTRATYPRHFPGIMARWSSLIGASHSKDYILWKYGGMASPGVTRVSEWGSVDKLVQEMKH--QGDDLFSIIKTQPLY-KSDGQVSA 190 79********************************************************************..779***********9.9******* PP Spond_N 97 efrvdkkhhlvSlvsklvPSPDWfvGvdsleLClkdcswveevtldLypwDaGtdsGvtysspnsptepqekieritssspsdpassFYdpe 188 +f+ d++++lvS +sk+ PSPDW vGvd+++LC+ +c+w++++t+dL+pwDaGtd+G+t+ s n +++pq++i++it ++++++ sF ++e FUN_001085-T1 191 SFKADSQRNLVSALSKMYPSPDWNVGVDRVNLCDGNCTWKKQITMDLFPWDAGTDDGITFISANRKSKPQQPIRNITRYTHQHSQGSFPNTE 282 ****************************************************************************************6654 PP >> TSP1_spondin Spondin-like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.3 5 2.1e+04 34 40 .. 61 67 .. 54 76 .. 0.56 2 ! 59.1 11.0 1.3e-19 5.4e-16 1 52 [] 320 371 .. 320 371 .. 0.99 3 ! 47.9 7.3 4.1e-16 1.7e-12 1 52 [] 380 434 .. 380 434 .. 0.97 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 5 TSP1_spondin 34 ggkpCpe 40 g +C+ FUN_001085-T1 61 RGVKCTI 67 3444554 PP == domain 2 score: 59.1 bits; conditional E-value: 1.3e-19 TSP1_spondin 1 CvvseWseWseCsktCgkGvqtRtRevivepqnggkpCpellerrkCneepC 52 C+vs+Ws+W++Cs+tCg+G+qtR R+v+++p+n+g pC +l+e+r+C + +C FUN_001085-T1 320 CEVSRWSSWTRCSVTCGQGQQTRGRAVTKKPTNDGIPCGNLSEHRPCIGSNC 371 ***************************************************9 PP == domain 3 score: 47.9 bits; conditional E-value: 4.1e-16 TSP1_spondin 1 CvvseWseWseCsktCgkGvqtRtRevivepqnggkpCpell...errkCneepC 52 C+vs+Ws WseC tC++G + RtR++++++ ggkpCp+ + + r+C+ ++C FUN_001085-T1 380 CKVSAWSGWSECRGTCSRGGRFRTRRILQKAGPGGKPCPDFNyliKWRRCKLPKC 434 ***************************************98878999******99 PP >> TSP_1 Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 1.9 0.39 1.7e+03 12 39 .. 53 82 .. 51 93 .. 0.76 2 ! 35.8 9.3 2.3e-12 9.6e-09 1 49 [] 323 371 .. 323 371 .. 0.88 3 ! 27.0 4.6 1.3e-09 5.4e-06 1 49 [] 383 434 .. 383 434 .. 0.88 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.39 TSP_1 12 TCgkGirvRqRtcksp..qkggepCtgeaq 39 C G++ R+ c +++++ +g+a+ FUN_001085-T1 53 LCVAGTKCRGVKCTILaeTQQNNMDNGKAT 82 6999********998766666777666665 PP == domain 2 score: 35.8 bits; conditional E-value: 2.3e-12 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp.qkggepCtgeaqeteaCkmkkC 49 s ws W+ CsvTCg+G+++R+R++ ++ ++g pC g+ +e ++C C FUN_001085-T1 323 SRWSSWTRCSVTCGQGQQTRGRAVTKKpTNDGIPC-GNLSEHRPCIGSNC 371 78***********************9978888888.66778999977777 PP == domain 3 score: 27.0 bits; conditional E-value: 1.3e-09 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp.qkggepCtg..eaqeteaCkmkkC 49 s ws Ws+C TC+ G r R+R++ ++ gg+pC++ ++ + Ck +kC FUN_001085-T1 383 SAWSGWSECRGTCSRGGRFRTRRILQKaGPGGKPCPDfnYLIKWRRCKLPKC 434 78**********************999999******8224567888999998 PP >> TSP1_CCN CCN3 Nov like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.088 3.7e+02 17 32 .. 9 25 .. 8 29 .. 0.79 2 ? -1.7 0.0 1.2 5e+03 20 35 .. 294 309 .. 293 311 .. 0.83 3 ? 13.9 10.1 1.6e-05 0.069 5 44 .] 325 371 .. 320 371 .. 0.72 4 ? 3.0 5.3 0.042 1.8e+02 5 24 .. 385 404 .. 380 409 .. 0.82 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.088 TSP1_CCN 17 lGvstRvs.ndneeCkl 32 G+stRv + +++C++ FUN_001085-T1 9 HGLSTRVVsSVSKHCHH 25 69****87367899986 PP == domain 2 score: -1.7 bits; conditional E-value: 1.2 TSP1_CCN 20 stRvsndneeCkleke 35 ++R+ ++ +C+++k+ FUN_001085-T1 294 KLRLMHTSGSCQKRKQ 309 6799999999*99887 PP == domain 3 score: 13.9 bits; conditional E-value: 1.6e-05 TSP1_CCN 5 steWsaCSktCGlGvstRvsn.......dneeCkleketrlCqlrpC 44 ++W+ CS tCG G tR + d C + +e r C +C FUN_001085-T1 325 WSSWTRCSVTCGQGQQTRGRAvtkkptnDGIPCGNLSEHRPCIGSNC 371 589***************76433344224446888888888887777 PP == domain 4 score: 3.0 bits; conditional E-value: 0.042 TSP1_CCN 5 steWsaCSktCGlGvstRvs 24 + Ws+C tC G R++ FUN_001085-T1 385 WSGWSECRGTCSRGGRFRTR 404 478***********988875 PP >> HTH_CLF_N Histone-lysine N-methyltransferase CLF, N-terminal HTH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.0031 13 14 30 .. 7 23 .. 6 26 .. 0.89 2 ? 2.6 0.0 0.036 1.5e+02 2 11 .. 131 140 .. 131 141 .. 0.90 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0031 HTH_CLF_N 14 qEyGlsdeVLeiLaqfi 30 q++Gls V++++++ FUN_001085-T1 7 QDHGLSTRVVSSVSKHC 23 99************976 PP == domain 2 score: 2.6 bits; conditional E-value: 0.036 HTH_CLF_N 2 segEDriLrm 11 s++ D+iL++ FUN_001085-T1 131 SHSKDYILWK 140 789******7 PP >> TSP1_ADAMTS Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 1.9 0.013 57 12 34 .. 53 75 .. 51 94 .. 0.78 2 ? -3.1 0.1 3.4 1.5e+04 37 45 .. 303 311 .. 297 321 .. 0.64 3 ? 11.8 10.4 7.7e-05 0.33 5 21 .. 327 343 .. 324 384 .. 0.67 4 ? 4.5 4.7 0.014 58 5 55 .] 387 434 .. 385 434 .. 0.77 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.013 TSP1_ADAMTS 12 tCGgGvqtRkvqCvqkkgkeles 34 C G++ R v+C+ + + ++ FUN_001085-T1 53 LCVAGTKCRGVKCTILAETQQNN 75 599**********9988877663 PP == domain 2 score: -3.1 bits; conditional E-value: 3.4 TSP1_ADAMTS 37 eCsaqkkPs 45 +C+++k+P+ FUN_001085-T1 303 SCQKRKQPH 311 577666665 PP == domain 3 score: 11.8 bits; conditional E-value: 7.7e-05 TSP1_ADAMTS 5 kWseCsktCGgGvqtRk 21 +W++Cs+tCG+G+qtR FUN_001085-T1 327 SWTRCSVTCGQGQQTRG 343 8**************84 PP == domain 4 score: 4.5 bits; conditional E-value: 0.014 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 WseC tC +G + R+ + qk g + C + + ++C+l++C FUN_001085-T1 387 GWSECRGTCSRGGRFRTRRILQKAGP---GGKPCPDFNYLIKWRRCKLPKC 434 5***********99888777777776...5677877777777777777777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (512 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 880 (0.034449); expected 510.9 (0.02) Passed bias filter: 499 (0.0195342); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 5112.94 // Query: FUN_001086-T1 [L=870] Description: FUN_001086 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-37 128.7 2.8 2e-20 73.6 0.5 2.5 2 Ank_2 Ankyrin repeats (3 copies) 1.3e-36 123.0 11.3 1.1e-07 32.2 0.1 5.7 6 Ank Ankyrin repeat 4.9e-36 122.4 4.9 5.2e-12 46.2 0.4 6.0 6 Ank_4 Ankyrin repeats (many copies) 4.5e-29 97.4 1.4 3e-05 24.5 0.0 5.5 5 Ank_3 Ankyrin repeat 8.8e-29 99.7 3.8 5.7e-10 39.8 0.2 4.6 4 Ank_5 Ankyrin repeats (many copies) 4.1e-16 60.0 9.9 4.1e-16 60.0 9.9 5.0 4 PRKG1_interact cGMP-dependent protein kinase interacting dom 0.00014 22.1 1.0 0.023 14.9 0.0 3.1 2 Ank_KRIT1 KRIT1 ankyrin-repeats domain 0.0026 18.1 2.0 7.3 7.0 0.2 3.3 3 ANK_LRRK2 LRRK2 ANK repeat 0.0042 18.0 0.8 0.54 11.3 0.1 2.6 2 Pyr_redox Pyridine nucleotide-disulphide oxidoreductase ------ inclusion threshold ------ 3.1 8.4 8.8 7 7.3 0.1 3.0 2 XRCC4_CC XRCC4 coiled-coil Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.6 0.5 7.9e-24 2e-20 4 88 .. 57 144 .. 54 160 .. 0.95 2 ! 54.8 0.1 5.9e-18 1.5e-14 23 89 .. 202 270 .. 187 271 .. 0.90 Alignments for each domain: == domain 1 score: 73.6 bits; conditional E-value: 7.9e-24 Ank_2 4 AakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadina 88 A+ +g+ e vk Ll +gad+n+q+ +g taLh A+ + ++v +L++hga ++ dn+g++aLh Aa++g++ei++ L+++gad+ a FUN_001086-T1 57 AVTSGDVEEVKKLLaKGADINHQNVDGLTALHQACIDENYDLVNFLVDHGARLDirDNEGWSALHAAASCGSVEIAQCLIDHGADVSA 144 8889*9***************9999*************************8888889****************************986 PP == domain 2 score: 54.8 bits; conditional E-value: 5.9e-18 Ank_2 23 nlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 +++dk g taLh+Aa++g+++++ lL++ g+d+n d +g+t+Lh A+ +g+ ++++lL+e+ga++ a+ FUN_001086-T1 202 EIKDKSGATALHVAASKGYVQVIGLLVQLGVDINakDVDGWTPLHAAVHWGQNDACELLAEHGANFSAR 270 367889**********************999999999***************************99876 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.9 0.0 0.00026 0.67 9 32 .. 57 80 .. 52 81 .. 0.87 2 ! 25.5 0.3 5.8e-09 1.5e-05 1 33 [] 82 114 .. 82 114 .. 0.96 3 ! 32.2 0.1 4.4e-11 1.1e-07 2 33 .] 116 147 .. 115 147 .. 0.95 4 ! 27.9 0.1 1e-09 2.7e-06 2 32 .. 208 238 .. 207 239 .. 0.94 5 ! 30.2 0.1 2e-10 5e-07 1 33 [] 240 272 .. 240 272 .. 0.96 6 ? -3.4 0.0 9.9 2.5e+04 2 10 .. 274 282 .. 273 292 .. 0.73 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00026 Ank 9 AaraghlevvklLLkhGAdvnard 32 A+ g++e vk LL +GAd+n ++ FUN_001086-T1 57 AVTSGDVEEVKKLLAKGADINHQN 80 7888**********77*****998 PP == domain 2 score: 25.5 bits; conditional E-value: 5.8e-09 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnardk 33 dG T+LH A+ ++++v++L++hGA +++rd+ FUN_001086-T1 82 DGLTALHQACIDENYDLVNFLVDHGARLDIRDN 114 7*********99**********99*******97 PP == domain 3 score: 32.2 bits; conditional E-value: 4.4e-11 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G+++LH+Aa++g++e+++ L++hGAdv a+++ FUN_001086-T1 116 GWSALHAAASCGSVEIAQCLIDHGADVSAVNN 147 9********************99******997 PP == domain 4 score: 27.9 bits; conditional E-value: 1e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G T+LH+Aa++g+++v+ lL++ G+d+na+d FUN_001086-T1 208 GATALHVAASKGYVQVIGLLVQLGVDINAKD 238 99*******99**********77******98 PP == domain 5 score: 30.2 bits; conditional E-value: 2e-10 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnardk 33 dG+TPLH+A+++g+ + ++lL +hGA+ ar+k FUN_001086-T1 240 DGWTPLHAAVHWGQNDACELLAEHGANFSARNK 272 8*********************99******997 PP == domain 6 score: -3.4 bits; conditional E-value: 9.9 Ank 2 GnTPLHlAa 10 G TP+ lA FUN_001086-T1 274 GSTPIDLAE 282 89**99985 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.0 0.0 2.5e-10 6.4e-07 3 38 .. 56 91 .. 54 92 .. 0.95 2 ! 46.2 0.4 2e-15 5.2e-12 1 50 [] 87 136 .. 87 136 .. 0.99 3 ! 8.0 0.0 0.0021 5.3 16 37 .. 135 156 .. 135 156 .. 0.94 4 ! 13.9 0.0 2.9e-05 0.074 23 46 .. 200 224 .. 191 227 .. 0.87 5 ! 37.6 0.0 1e-12 2.7e-09 1 42 [. 212 253 .. 212 254 .. 0.97 6 ! 12.6 0.0 7.4e-05 0.19 4 37 .. 248 281 .. 247 281 .. 0.93 Alignments for each domain: == domain 1 score: 30.0 bits; conditional E-value: 2.5e-10 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAa 38 +A+ sg++e +k Ll++gadin+++ +g taLh A+ FUN_001086-T1 56 SAVTSGDVEEVKKLLAKGADINHQNVDGLTALHQAC 91 6899*******************************8 PP == domain 2 score: 46.2 bits; conditional E-value: 2e-15 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh+A+++++++l+ +L+++ga ++ +d++g++aLh Aas+g++e++++L+ FUN_001086-T1 87 LHQACIDENYDLVNFLVDHGARLDIRDNEGWSALHAAASCGSVEIAQCLI 136 8************************************************8 PP == domain 3 score: 8.0 bits; conditional E-value: 0.0021 Ank_4 16 LlengadinatdgngetaLhfA 37 L+++gad+ a++++ge +L+ A FUN_001086-T1 135 LIDHGADVSAVNNEGELPLDLA 156 89*****************977 PP == domain 4 score: 13.9 bits; conditional E-value: 2.9e-05 Ank_4 23 inat.dgngetaLhfAasngnlevl 46 in+ d++g taLh Aas+g+++v+ FUN_001086-T1 200 INEIkDKSGATALHVAASKGYVQVI 224 89999*****************998 PP == domain 5 score: 37.6 bits; conditional E-value: 1e-12 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngn 42 lh+Aa++g ++++ lL++ g+dina d +g+t+Lh A+++g+ FUN_001086-T1 212 LHVAASKGYVQVIGLLVQLGVDINAKDVDGWTPLHAAVHWGQ 253 8**************************************995 PP == domain 6 score: 12.6 bits; conditional E-value: 7.4e-05 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfA 37 A+++g+ ++++lL e+ga++ a+++ g t+++ A FUN_001086-T1 248 AVHWGQNDACELLAEHGANFSARNKMGSTPIDLA 281 788***************************9876 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.0 0.00062 1.6 4 31 .] 52 78 .. 50 78 .. 0.94 2 ! 20.2 0.1 3.1e-07 0.0008 1 30 [. 82 110 .. 82 111 .. 0.93 3 ! 24.5 0.0 1.2e-08 3e-05 1 30 [. 115 143 .. 115 144 .. 0.95 4 ! 18.4 0.0 1.2e-06 0.003 2 31 .] 208 236 .. 207 236 .. 0.96 5 ! 18.8 0.0 8.6e-07 0.0022 1 30 [. 240 268 .. 240 269 .. 0.89 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00062 Ank_3 4 tpLhlAarngrleivklLleklgadina 31 t + A+ +g++e vk Ll +gadin+ FUN_001086-T1 52 TVFLSAVTSGDVEEVKKLLA-KGADINH 78 78999*******99******.*****97 PP == domain 2 score: 20.2 bits; conditional E-value: 3.1e-07 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 dg t+Lh+A++ ++++v +L++ +ga ++ FUN_001086-T1 82 DGLTALHQACIDENYDLVNFLVD-HGARLD 110 699********************.9*9876 PP == domain 3 score: 24.5 bits; conditional E-value: 1.2e-08 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+++Lh Aa++g++ei+++L++ +gad+ FUN_001086-T1 115 EGWSALHAAASCGSVEIAQCLID-HGADVS 143 59*********************.****96 PP == domain 4 score: 18.4 bits; conditional E-value: 1.2e-06 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g t+Lh+Aa+ g ++++ lL++ lg+dina FUN_001086-T1 208 GATALHVAASKGYVQVIGLLVQ-LGVDINA 236 78********************.*****96 PP == domain 5 score: 18.8 bits; conditional E-value: 8.6e-07 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 dg+tpLh A++ g+ ++++lL e +ga++ FUN_001086-T1 240 DGWTPLHAAVHWGQNDACELLAE-HGANFS 268 79**************8888888.***975 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.0 0.4 3e-11 7.7e-08 1 54 [. 69 121 .. 69 121 .. 0.94 2 ! 39.8 0.2 2.2e-13 5.7e-10 1 56 [] 102 156 .. 102 156 .. 0.93 3 ! 32.6 0.0 4.2e-11 1.1e-07 12 54 .. 204 246 .. 201 248 .. 0.94 4 ! 15.0 0.0 1.3e-05 0.034 18 56 .] 243 281 .. 241 281 .. 0.96 Alignments for each domain: == domain 1 score: 33.0 bits; conditional E-value: 3e-11 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 Ll+ g ad+n+++ +g t+Lh A+ ++++v++L+++g+ l ++d+eg+++l+ FUN_001086-T1 69 LLAKG-ADINHQNVDGLTALHQACIDENYDLVNFLVDHGARLDIRDNEGWSALH 121 78999.88888888999***********************************96 PP == domain 2 score: 39.8 bits; conditional E-value: 2.2e-13 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 L+++g a+l+++d+eg +Lh Aa++g+ ei++ L+++g+d+ + ++eg++pldlA FUN_001086-T1 102 LVDHG-ARLDIRDNEGWSALHAAASCGSVEIAQCLIDHGADVSAVNNEGELPLDLA 156 89***.77777777777**************************************9 PP == domain 3 score: 32.6 bits; conditional E-value: 4.2e-11 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 +d+ g t+LhvAa++g+ +++ lL+ gvd+n+kd +g+tpl+ FUN_001086-T1 204 KDKSGATALHVAASKGYVQVIGLLVQLGVDINAKDVDGWTPLH 246 7899*************************************98 PP == domain 4 score: 15.0 bits; conditional E-value: 1.3e-05 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 tpLh A++ g ++ +lL ++g++ +++++g+tp+dlA FUN_001086-T1 243 TPLHAAVHWGQNDACELLAEHGANFSARNKMGSTPIDLA 281 9*************************************9 PP >> PRKG1_interact cGMP-dependent protein kinase interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.5 4.7 1.2e+04 34 58 .. 17 41 .. 9 54 .. 0.42 2 ? -2.9 0.7 6.2 1.6e+04 23 23 .. 367 367 .. 328 405 .. 0.53 3 ? -5.9 12.0 10 2.6e+04 8 60 .. 664 721 .. 659 745 .. 0.52 4 ! 60.0 9.9 1.6e-19 4.1e-16 12 101 .] 795 867 .. 787 867 .. 0.82 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 4.7 PRKG1_interact 34 lekvkqkqeslskrssllelekrEk 58 l+k +++ ++ +++++ e +r + FUN_001086-T1 17 LQKRQESLKRWTTSETAKESADRSR 41 2222222223333333333333322 PP == domain 2 score: -2.9 bits; conditional E-value: 6.2 PRKG1_interact 23 l 23 FUN_001086-T1 367 N 367 1 PP == domain 3 score: -5.9 bits; conditional E-value: 10 PRKG1_interact 8 kalqenerLkekleelkkelaeiksklekvkqkqe.....slskrssllelekrEkra 60 ++++e e+L+++ ++ + e++s+ ++ k+k++ +++++s+ +e+ r kr FUN_001086-T1 664 EERREREKLQDRGRKKPGKEGESESRTDREKEKEKvteekEVDDSSQSAEARARRKRM 721 4555555555555555445555555555554433322222444444444443333333 PP == domain 4 score: 60.0 bits; conditional E-value: 1.6e-19 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgALiRViskLsk 101 + +++ke+l+e++ el+e k k ek+ + k++lerk s++ee+lk+l++Lka+NqrLkdENgALiRViskLs+ FUN_001086-T1 795 DPQKMKERLQEVQLELQEYKIKYEKAL-----------------QAKEELERKYSNVEEDLKQLSDLKADNQRLKDENGALIRVISKLSR 867 556667777777777777777777654.................45788***************************************96 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.2 0.025 63 48 107 .. 85 138 .. 52 163 .. 0.47 2 ! 14.9 0.0 8.9e-06 0.023 37 135 .. 200 291 .. 185 297 .. 0.82 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.025 Ank_KRIT1 48 eslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 +l++A+ + +++L++ G d + ++e + l Aa + +++ + l+d+ FUN_001086-T1 85 TALHQACIDENYDLVNFLVDHGAR-LD---I--RDNEGWSALHAAASCGSVEIAQCLIDH 138 335555555555555555555532.12...1..122222233333333344444444433 PP == domain 2 score: 14.9 bits; conditional E-value: 8.9e-06 Ank_KRIT1 37 iLnvrekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgen 132 i ++++k + +l+ Aa G +v+ lL++lG d + + + tPl Aa+ ++ + +ll ++ r+ g+t++++a+ g FUN_001086-T1 200 INEIKDKS-GATALHVAASKGYVQVIGLLVQLGV-DIN-----AKDVDGWTPLHAAVHWGQNDACELLAEHGANFSARNKMGSTPIDLAEPDMGRM 288 44555665.7889*******************94.444.....4556667*******************998777788899********9888877 PP Ank_KRIT1 133 wee 135 ee FUN_001086-T1 289 LEE 291 665 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.9 0.0 0.006 15 38 89 .. 57 108 .. 46 114 .. 0.78 2 ! 7.0 0.2 0.0029 7.3 35 79 .. 120 164 .. 113 180 .. 0.83 3 ? 2.5 0.0 0.068 1.7e+02 95 122 .. 210 236 .. 197 241 .. 0.59 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.006 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkktkt.esliyqvCErgsplelvelllssgvr 89 a + gdv + ll gad+n+++ + + + q C ++ +lv+ l+++g+r FUN_001086-T1 57 AVTSGDVEEVKKLLAKGADINHQNVDgLTALHQACIDEN-YDLVNFLVDHGAR 108 667778888889999999999876441566889998766.9999999999986 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0029 ANK_LRRK2 35 LekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplel 79 L+ a + g v +a cl+ gadv +++ l + E ++ +l FUN_001086-T1 120 LHAAASCGSVEIAQCLIDHGADVSAVNNEGELPLDLAEEEDMEDL 164 56677778899*************999999988888888776555 PP == domain 3 score: 2.5 bits; conditional E-value: 0.068 ANK_LRRK2 95 kaLavsvkrgdgevvsllLkkLgLDlan 122 +aL+v+ +g +v+ lL +Lg+D++ FUN_001086-T1 210 TALHVAASKGYVQVIG-LLVQLGVDINA 236 4555555555555554.34456666554 PP >> Pyr_redox Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.1 0.031 78 30 77 .. 20 67 .. 16 71 .. 0.88 2 ! 11.3 0.1 0.00021 0.54 12 57 .. 129 176 .. 125 191 .. 0.90 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.031 Pyr_redox 30 rrdellrglDeeiakllqeklekn.gievllntkveeiegngdgvesvk 77 r+++l r e+ak+ +++ +k+ +i++ l+t + +++gd ve+vk FUN_001086-T1 20 RQESLKRWTTSETAKESADRSRKKtKIKFSLGTVFLSAVTSGD-VEEVK 67 6677779999999********9999**************9998.88876 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00021 Pyr_redox 12 lElAealarlgkkVtvverrdell..rglDeeiakllqeklekngiev 57 +E A+ l ++g++V+ v ++ el +++e++++ll++++e +gi+v FUN_001086-T1 129 VEIAQCLIDHGADVSAVNNEGELPldLAEEEDMEDLLTDEIERLGIDV 176 8****************99988765999******************98 PP >> XRCC4_CC XRCC4 coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 4.2 0.1 2.6e+02 26 59 .. 797 830 .. 786 834 .. 0.84 2 ? 7.3 0.1 0.0027 7 15 39 .. 838 862 .. 832 867 .. 0.86 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.1 XRCC4_CC 26 ehLqkEnerLlrdwsdvqerlekyveakEelead 59 +++++ ++++ ++++ + + ek +akEele+ FUN_001086-T1 797 QKMKERLQEVQLELQEYKIKYEKALQAKEELERK 830 6777777888899999999*************85 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0027 XRCC4_CC 15 LdqiaelqaknehLqkEnerLlrdw 39 L+q+++l+a n++L+ En L+r FUN_001086-T1 838 LKQLSDLKADNQRLKDENGALIRVI 862 8899****************99865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (870 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2345 (0.0917988); expected 510.9 (0.02) Passed bias filter: 610 (0.0238794); expected 510.9 (0.02) Passed Vit filter: 139 (0.00544138); expected 25.5 (0.001) Passed Fwd filter: 44 (0.00172245); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.65u 0.43s 00:00:01.08 Elapsed: 00:00:00.45 # Mc/sec: 7781.56 // Query: FUN_001086-T2 [L=670] Description: FUN_001086 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-17 61.3 0.4 3.7e-07 30.6 0.1 2.7 3 Ank Ankyrin repeat 2.8e-16 60.5 9.9 2.8e-16 60.5 9.9 4.7 4 PRKG1_interact cGMP-dependent protein kinase interacting dom 2.9e-16 59.7 0.9 3e-10 40.5 0.1 3.1 3 Ank_4 Ankyrin repeats (many copies) 6.1e-15 56.1 0.1 1.2e-14 55.1 0.1 1.4 1 Ank_2 Ankyrin repeats (3 copies) 4.6e-11 43.3 0.0 7.7e-08 33.0 0.0 2.4 2 Ank_5 Ankyrin repeats (many copies) 2e-10 40.3 0.1 0.0016 19.2 0.0 2.5 2 Ank_3 Ankyrin repeat 0.0073 16.5 0.0 0.018 15.3 0.0 1.6 1 Ank_KRIT1 KRIT1 ankyrin-repeats domain ------ inclusion threshold ------ 0.019 15.5 6.1 0.019 15.5 6.1 3.6 3 UPF0242 Uncharacterised protein family (UPF0242) N-te 2.2 9.0 8.8 5.2 7.8 0.1 2.7 2 XRCC4_CC XRCC4 coiled-coil Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.1 6.9e-10 2e-06 2 32 .. 22 52 .. 21 53 .. 0.94 2 ! 30.6 0.1 1.3e-10 3.7e-07 1 33 [] 54 86 .. 54 86 .. 0.96 3 ? -3.0 0.0 6.4 1.8e+04 2 10 .. 88 96 .. 87 107 .. 0.73 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 6.9e-10 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G T+LH+Aa++g+++v+ lL++ G+d+na+d FUN_001086-T2 22 GATALHVAASKGYVQVIGLLVQLGVDINAKD 52 99*******99**********77******98 PP == domain 2 score: 30.6 bits; conditional E-value: 1.3e-10 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnardk 33 dG+TPLH+A+++g+ + ++lL +hGA+ ar+k FUN_001086-T2 54 DGWTPLHAAVHWGQNDACELLAEHGANFSARNK 86 8*********************99******997 PP == domain 3 score: -3.0 bits; conditional E-value: 6.4 Ank 2 GnTPLHlAa 10 G TP+ lA FUN_001086-T2 88 GSTPIDLAE 96 89**99985 PP >> PRKG1_interact cGMP-dependent protein kinase interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.2 3.0 9 2.6e+04 46 46 .. 155 155 .. 99 204 .. 0.60 2 ? -4.0 0.9 9 2.6e+04 43 56 .. 241 254 .. 219 265 .. 0.47 3 ? -5.6 12.2 9 2.6e+04 8 60 .. 464 521 .. 459 547 .. 0.53 4 ! 60.5 9.9 9.8e-20 2.8e-16 12 101 .] 595 667 .. 587 667 .. 0.82 Alignments for each domain: == domain 1 score: -4.2 bits; conditional E-value: 9 PRKG1_interact 46 k 46 + FUN_001086-T2 155 R 155 1 PP == domain 2 score: -4.0 bits; conditional E-value: 9 PRKG1_interact 43 slskrssllelekr 56 s s+++s e +++ FUN_001086-T2 241 SESEETSSDEEDQE 254 22222222233333 PP == domain 3 score: -5.6 bits; conditional E-value: 9 PRKG1_interact 8 kalqenerLkekleelkkelaeiksklekvkqkqe.....slskrssllelekrEkra 60 ++++e e+L+++ ++ + e++s+ ++ k+k++ +++++s+ +e+ r kr FUN_001086-T2 464 EERREREKLQDRGRKKPGKEGESESRTDREKEKEKvteekEVDDSSQSAEARARRKRM 521 4555555555555555445555555555544433322222444444444444333333 PP == domain 4 score: 60.5 bits; conditional E-value: 9.8e-20 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgALiRViskLsk 101 + +++ke+l+e++ el+e k k ek+ + k++lerk s++ee+lk+l++Lka+NqrLkdENgALiRViskLs+ FUN_001086-T2 595 DPQKMKERLQEVQLELQEYKIKYEKAL-----------------QAKEELERKYSNVEEDLKQLSDLKADNQRLKDENGALIRVISKLSR 667 556667777777777777777777654.................45788***************************************96 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 1.2e-05 0.034 23 49 .. 14 41 .. 5 42 .. 0.86 2 ! 40.5 0.1 1.1e-13 3e-10 1 49 [. 26 74 .. 26 74 .. 0.96 3 ! 17.9 0.1 1.4e-06 0.004 1 37 [. 59 95 .. 59 95 .. 0.96 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1.2e-05 Ank_4 23 inat.dgngetaLhfAasngnlevlklL 49 in+ d++g taLh Aas+g+++v+ lL FUN_001086-T2 14 INEIkDKSGATALHVAASKGYVQVIGLL 41 89999******************98666 PP == domain 2 score: 40.5 bits; conditional E-value: 1.1e-13 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+Aa++g ++++ lL++ g+dina d +g+t+Lh A+++g+ ++++lL FUN_001086-T2 26 LHVAASKGYVQVIGLLVQLGVDINAKDVDGWTPLHAAVHWGQNDACELL 74 8****************************************98888876 PP == domain 3 score: 17.9 bits; conditional E-value: 1.4e-06 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfA 37 lhaA+++g+ ++++lL e+ga++ a+++ g t+++ A FUN_001086-T2 59 LHAAVHWGQNDACELLAEHGANFSARNKMGSTPIDLA 95 8********************************9876 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.1 0.1 4.1e-18 1.2e-14 23 89 .. 16 84 .. 4 85 .. 0.91 Alignments for each domain: == domain 1 score: 55.1 bits; conditional E-value: 4.1e-18 Ank_2 23 nlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 +++dk g taLh+Aa++g+++++ lL++ g+d+n d +g+t+Lh A+ +g+ ++++lL+e+ga++ a+ FUN_001086-T2 16 EIKDKSGATALHVAASKGYVQVIGLLVQLGVDINakDVDGWTPLHAAVHWGQNDACELLAEHGANFSAR 84 366889**********************999999999***************************99876 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.0 0.0 2.7e-11 7.7e-08 12 54 .. 18 60 .. 15 62 .. 0.94 2 ! 15.5 0.0 8.8e-06 0.025 18 56 .] 57 95 .. 55 95 .. 0.96 Alignments for each domain: == domain 1 score: 33.0 bits; conditional E-value: 2.7e-11 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 +d+ g t+LhvAa++g+ +++ lL+ gvd+n+kd +g+tpl+ FUN_001086-T2 18 KDKSGATALHVAASKGYVQVIGLLVQLGVDINAKDVDGWTPLH 60 7899*************************************98 PP == domain 2 score: 15.5 bits; conditional E-value: 8.8e-06 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 tpLh A++ g ++ +lL ++g++ +++++g+tp+dlA FUN_001086-T2 57 TPLHAAVHWGQNDACELLAEHGANFSARNKMGSTPIDLA 95 9*************************************9 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 7.7e-07 0.0022 2 31 .] 22 50 .. 21 50 .. 0.96 2 ! 19.2 0.0 5.6e-07 0.0016 1 30 [. 54 82 .. 54 83 .. 0.89 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 7.7e-07 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g t+Lh+Aa+ g ++++ lL++ lg+dina FUN_001086-T2 22 GATALHVAASKGYVQVIGLLVQ-LGVDINA 50 78********************.*****96 PP == domain 2 score: 19.2 bits; conditional E-value: 5.6e-07 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 dg+tpLh A++ g+ ++++lL e +ga++ FUN_001086-T2 54 DGWTPLHAAVHWGQNDACELLAE-HGANFS 82 79**************8888888.***975 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 6.2e-06 0.018 37 135 .. 14 105 .. 6 111 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 6.2e-06 Ank_KRIT1 37 iLnvrekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgen 132 i ++++k + +l+ Aa G +v+ lL++lG d + + + tPl Aa+ ++ + +ll ++ r+ g+t++++a+ g FUN_001086-T2 14 INEIKDKS-GATALHVAASKGYVQVIGLLVQLGV-DIN-----AKDVDGWTPLHAAVHWGQNDACELLAEHGANFSARNKMGSTPIDLAEPDMGRM 102 44556666.7889*******************94.444.....4556667*******************998777788899********9888877 PP Ank_KRIT1 133 wee 135 ee FUN_001086-T2 103 LEE 105 665 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -10.1 11.9 9 2.6e+04 71 143 .. 175 245 .. 145 272 .. 0.44 2 ? -4.5 9.5 8.8 2.5e+04 82 154 .. 456 525 .. 423 547 .. 0.56 3 ? 15.5 6.1 6.6e-06 0.019 68 141 .. 582 655 .. 560 664 .. 0.90 Alignments for each domain: == domain 1 score: -10.1 bits; conditional E-value: 9 UPF0242 71 eekeallteedaedlkileeeleelqseeeeleee....lsqkeeeleklkeekeqlklkleqisqdfaefklesee 143 ++k te d+e+ + ee +ee++ eee s + + + + ++++ k e+ s+ +e esee FUN_001086-T2 175 PSKDDSGTESDTEG------SSEEESEEESDQEEEtggtTSTVKPVAPRPEVKSNSISPKPEEESESEDESGSESEE 245 33333333333222......223333333333333122122222222222222223333333333333333333333 PP == domain 2 score: -4.5 bits; conditional E-value: 8.8 UPF0242 82 aedlkileeeleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfaefkleseeqlkekqlllne 154 ++ k +ee +e+++ +++ +++ + e + +eke+ k + + ++++++ ++ +e + ++k++l+++ FUN_001086-T2 456 VPSWKRRQEERREREKLQDRGRKKPGKEGESESRTDREKEKEK--VTE-EKEVDDSSQSAEARARRKRMLIEK 525 3344444444444444444433333333333334444444333..333.468888888888888888888875 PP == domain 3 score: 15.5 bits; conditional E-value: 6.6e-06 UPF0242 68 sfleekeallteedaedlkileeele.elqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfaefkles 141 sf + k + +te+d++++k+ +e++ elq+ + + e+ l+ kee +k+ + +e lk +l + + d++++k e FUN_001086-T2 582 SFGSTKANAVTETDPQKMKERLQEVQlELQEYKIKYEKALQAKEELERKYSNVEEDLK-QLSDLKADNQRLKDEN 655 67889******************9986899999999**********************.***********99875 PP >> XRCC4_CC XRCC4 coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 4.2 0.066 1.9e+02 26 59 .. 597 630 .. 586 634 .. 0.84 2 ? 7.8 0.1 0.0018 5.2 15 39 .. 638 662 .. 632 667 .. 0.86 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.066 XRCC4_CC 26 ehLqkEnerLlrdwsdvqerlekyveakEelead 59 +++++ ++++ ++++ + + ek +akEele+ FUN_001086-T2 597 QKMKERLQEVQLELQEYKIKYEKALQAKEELERK 630 6777777888899999999*************85 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0018 XRCC4_CC 15 LdqiaelqaknehLqkEnerLlrdw 39 L+q+++l+a n++L+ En L+r FUN_001086-T2 638 LKQLSDLKADNQRLKDENGALIRVI 662 8899****************99865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (670 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2856 (0.111803); expected 510.9 (0.02) Passed bias filter: 769 (0.0301037); expected 510.9 (0.02) Passed Vit filter: 168 (0.00657663); expected 25.5 (0.001) Passed Fwd filter: 52 (0.00203562); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.67u 0.43s 00:00:01.10 Elapsed: 00:00:00.45 # Mc/sec: 6028.29 // Query: FUN_001087-T1 [L=263] Description: FUN_001087 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-08 33.8 15.2 5.6e-08 33.8 15.2 2.6 2 PRKG1_interact cGMP-dependent protein kinase interacting dom 0.0051 17.9 3.8 0.0051 17.9 3.8 2.8 3 YabA Initiation control protein YabA 0.0093 16.3 1.3 0.0093 16.3 1.3 2.8 3 Syntaxin Syntaxin ------ inclusion threshold ------ 0.026 14.9 5.5 0.047 14.1 5.5 1.4 1 COG3_N Conserved oligomeric Golgi complex subunit 3, 0.048 14.6 2.7 0.048 14.6 2.7 2.2 2 FlaC_arch Flagella accessory protein C (FlaC) 0.051 13.2 0.6 0.051 13.2 0.6 1.6 2 2-ph_phosp 2-phosphosulpholactate phosphatase 0.11 12.6 5.0 0.17 12.0 3.3 2.1 2 Nup54_57_C NUP57/Nup54 C-terminal domain 0.14 12.7 5.7 0.19 12.2 4.9 1.6 1 DUF1664 Protein of unknown function (DUF1664) 0.79 9.8 5.6 0.47 10.5 3.9 1.6 1 Lipl32 Surface lipoprotein of Spirochaetales order Domain annotation for each model (and alignments): >> PRKG1_interact cGMP-dependent protein kinase interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 4.3 1.5 4.3e+03 15 65 .. 77 127 .. 64 139 .. 0.75 2 ! 33.8 15.2 2e-11 5.6e-08 18 100 .. 175 257 .. 151 258 .. 0.70 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1.5 PRKG1_interact 15 rLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerki 65 r ++k+++ + a+ ++ +e ++ e+ s +++l + k E+ a +r++ FUN_001087-T1 77 RDRRKIKDDGETNANDEASVEGATAAPEESSPKKTLKKDRKSENSAHKRQA 127 557888888888888888888888777777777888887888877777765 PP == domain 2 score: 33.8 bits; conditional E-value: 2e-11 PRKG1_interact 18 ekleelkkelaeiksklekvkq.kqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgALiRViskLs 100 e+ e++ + ++++s++e+ q ++ ++ ++ l ++++ E +le sele+ k +++L+++N+rLkdEN L+RVis+Ls FUN_001087-T1 175 EEQAEVNPKRESTNSRIEQKVQnDSQTIQMQQLLEKIDDYEA-QLEDYKSELEKVNKEVDQLRQDNNRLKDENSSLLRVISQLS 257 333344445555666666554414445555666666677775.5777779*********************************9 PP >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 9 2.6e+04 58 81 .. 15 38 .. 11 38 .. 0.59 2 ? -3.0 5.1 5.4 1.5e+04 26 65 .. 160 200 .. 80 211 .. 0.65 3 ! 17.9 3.8 1.8e-06 0.0051 3 53 .. 204 254 .. 202 263 .] 0.89 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 9 YabA 58 kekekkkelsegkenLaklYeeGF 81 k+++k+ + se ++ + Y +GF FUN_001087-T1 15 KSRHKRGDRSERRQRGVNRYGDGF 38 444555556666666666677776 PP == domain 2 score: -3.0 bits; conditional E-value: 5.4 YabA 26 elkeelaelleena.eLeiEnekLrerlkkeeekekekkke 65 ++k+++++ + n+ e + E + re +++ e++ +++++ FUN_001087-T1 160 QVKSNTQQNEQANDdEEQAEVNPKRESTNSRIEQKVQNDSQ 200 33333333333322123334444444444444444444444 PP == domain 3 score: 17.9 bits; conditional E-value: 1.8e-06 YabA 3 kkelfdqleeleeqleellkeleelkeelaelleenaeLeiEnekLrerlk 53 ++l++++++ e qle+ +ele++ +e+++l ++n++L+ En+ L + ++ FUN_001087-T1 204 MQQLLEKIDDYEAQLEDYKSELEKVNKEVDQLRQDNNRLKDENSSLLRVIS 254 5799****************************************9988774 PP >> Syntaxin Syntaxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.2 0.79 2.3e+03 45 90 .. 112 126 .. 62 140 .. 0.64 2 ? -2.0 9.3 1.4 3.9e+03 57 115 .. 155 217 .. 109 223 .. 0.72 3 ! 16.3 1.3 3.3e-06 0.0093 2 46 .. 216 260 .. 215 263 .] 0.93 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.79 Syntaxin 45 lkkrmesdikevkkraesikarLealdksneenekksgegsavdRi 90 lkk+ + e+sa +R+ FUN_001087-T1 112 LKKDRK-------------------------------SENSAHKRQ 126 222222...............................233333333 PP == domain 2 score: -2.0 bits; conditional E-value: 1.4 Syntaxin 57 kkraesikarLealdksneenekks...gegsavdRirks.qtaaLrkklkevMleynelrek 115 a+++k++ ++ +++n+++e+ + +++s +Ri++ q ++ + ++++++++ + +++ FUN_001087-T1 155 DAVAKQVKSNTQQNEQANDDEEQAEvnpKRESTNSRIEQKvQNDSQTIQMQQLLEKIDDYEAQ 217 445666666666666666666555555699******976515667777888777766665554 PP == domain 3 score: 16.3 bits; conditional E-value: 3.3e-06 Syntaxin 2 enleeffkeveeikkeieelredvkkLqkqnsklltkarrlkklk 46 +le++ +e e+++ke+++lr+d ++L+++ns+ll ++l+++k FUN_001087-T1 216 AQLEDYKSELEKVNKEVDQLRQDNNRLKDENSSLLRVISQLSSMK 260 6799999*************************9999999999998 PP >> COG3_N Conserved oligomeric Golgi complex subunit 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 5.5 1.7e-05 0.047 8 65 .. 199 256 .. 191 259 .. 0.90 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.7e-05 COG3_N 8 skeeecdelleqtdetlelleeleekfksvsektsslqeaceeLleeqkrleelaeei 65 s++ ++++lle++d+ + +le+ +++ ++v+++ ++l+++ ++L +e+++l ++ ++ FUN_001087-T1 199 SQTIQMQQLLEKIDDYEAQLEDYKSELEKVNKEVDQLRQDNNRLKDENSSLLRVISQL 256 5666899******************************************999888776 PP >> FlaC_arch Flagella accessory protein C (FlaC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.2 0.88 2.5e+03 5 18 .. 191 204 .. 184 208 .. 0.63 2 ? 14.6 2.7 1.7e-05 0.048 1 42 [. 210 251 .. 210 258 .. 0.91 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.88 FlaC_arch 5 lEnklekleselet 18 +E+k+++ + ++++ FUN_001087-T1 191 IEQKVQNDSQTIQM 204 66666666666655 PP == domain 2 score: 14.6 bits; conditional E-value: 1.7e-05 FlaC_arch 1 ridelEnklekleseletlrkeneeisksveeieenvkklls 42 +id+ E +le+ +sele + ke +++++++++++++ ll FUN_001087-T1 210 KIDDYEAQLEDYKSELEKVNKEVDQLRQDNNRLKDENSSLLR 251 899*******************************98777775 PP >> 2-ph_phosp 2-phosphosulpholactate phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 1.1 3.1e+03 161 195 .. 82 117 .. 80 120 .. 0.76 2 ? 13.2 0.6 1.8e-05 0.051 126 202 .. 129 207 .. 122 223 .. 0.79 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1.1 2-ph_phosp 161 lkkeeelelnDealaalalyeq.kedllellkessh 195 +k+++e+++nDea + a + +++++++lk+ ++ FUN_001087-T1 82 IKDDGETNANDEASVEGATAAPeESSPKKTLKKDRK 117 566778899999999888888767888888888766 PP == domain 2 score: 13.2 bits; conditional E-value: 1.8e-05 2-ph_phosp 126 eylkekake..vvivcaGtegrfsleDtlcAgalaeelkkeeelelnDealaalalyeq..kedllellkesshgkrLkel 202 ++l+ek + vvi+ aGt+g+ eD++ A + ++ ++ +e + +De a + ++ ++++++ +++ s+ ++++l FUN_001087-T1 129 RHLREKRRStgVVIMPAGTDGDSEDEDAV-AKQVKSNTQQ-NEQANDDEEQAEVNPKREstNSRIEQKVQNDSQTIQMQQL 207 67888877778****************75.7788888877.4577788888888877776679999999999888888776 PP >> Nup54_57_C NUP57/Nup54 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 3.3 5.9e-05 0.17 9 28 .. 212 231 .. 210 232 .. 0.95 2 ? 9.1 1.7 0.00047 1.3 8 28 .. 218 238 .. 218 238 .. 0.97 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.9e-05 Nup54_57_C 9 eDYekQLqHLkKElEeikkD 28 +DYe+QL k ElE++ k+ FUN_001087-T1 212 DDYEAQLEDYKSELEKVNKE 231 7*****************98 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00047 Nup54_57_C 8 LeDYekQLqHLkKElEeikkD 28 LeDY L +KE++++++D FUN_001087-T1 218 LEDYKSELEKVNKEVDQLRQD 238 9******************98 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 4.9 6.8e-05 0.19 49 114 .. 194 257 .. 184 262 .. 0.84 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 6.8e-05 DUF1664 49 qleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeavegle 114 ++++ s++++ ++L ++id +++l++ k +++++ev ++r+d +++k++ +s+ +++++l FUN_001087-T1 194 KVQNDSQTIQ--MQQLLEKIDDYEAQLEDYKSELEKVNKEVDQLRQDNNRLKDENSSLLRVISQLS 257 4444455554..4689**********************************************9996 PP >> Lipl32 Surface lipoprotein of Spirochaetales order # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 3.9 0.00017 0.47 92 142 .. 153 201 .. 107 211 .. 0.89 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00017 Lipl32 92 dkekikkaakskklqtlasdddsselpkepkgkkynsllriksevsnPaka 142 d++ ++k++ks++ q+ + +dd+++ +pk ++ ns ri+++v+n +++ FUN_001087-T1 153 DEDAVAKQVKSNTQQNEQANDDEEQAEVNPKRESTNS--RIEQKVQNDSQT 201 678899******************************9..666668888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (263 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4424 (0.173185); expected 510.9 (0.02) Passed bias filter: 981 (0.0384028); expected 510.9 (0.02) Passed Vit filter: 190 (0.00743785); expected 25.5 (0.001) Passed Fwd filter: 50 (0.00195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.50u 0.39s 00:00:00.89 Elapsed: 00:00:00.43 # Mc/sec: 2455.00 // Query: FUN_001088-T1 [L=539] Description: FUN_001088 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-82 275.8 1.9 5.7e-82 275.1 1.9 1.4 1 ApeC C-terminal domain of apextrin ------ inclusion threshold ------ 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 DUF6753 Family of unknown function (DUF6753) Domain annotation for each model (and alignments): >> ApeC C-terminal domain of apextrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 275.1 1.9 4.5e-86 5.7e-82 1 208 [] 140 342 .. 140 342 .. 0.99 Alignments for each domain: == domain 1 score: 275.1 bits; conditional E-value: 4.5e-86 ApeC 1 WPaGsYGlPkpvsgCpesegveWktGvrfqdtedddekskksaslhlagsvskegvkqefCikkdtkgeeerpeWpeGkYCiykkgdeCPagleeG 96 WP+G+YGlPkpv+gCp s g++WktG+rf+dtedd ++++s+s+hlag++s+ g+++efCik++++g + Wp GkYCiykkg CP+gleeG FUN_001088-T1 140 WPSGTYGLPKPVDGCPVSDGFQWKTGYRFHDTEDDGTENQHSDSFHLAGEFSDVGIRHEFCIKTTEDGGGR---WPDGKYCIYKKGLDCPSGLEEG 232 *******************************************************************9999...********************** PP ApeC 97 yirwdDensevdnenkesGtlPeGvYdentliefCCstkGskdtaikLPldspfyLlayesasCqkvkgakvteeflkfddedeenkdaeggahPy 192 +++wdDen+ dn+n+++G+lPeG ++e+t+i fCCst+G + i LP +spf L+ayes Cqkvkg++v +ef+kfdded+ n d+egg++Py FUN_001088-T1 233 FVIWDDENK--DNKNSKRGELPEGLFNEDTKIFFCCSTSGPVGKEIILPNKSPFLLFAYESILCQKVKGMNVITEFIKFDDEDRGNIDYEGGEFPY 326 *******99..899********************************************************************************** PP ApeC 193 lvtkkkkdltlyyCyY 208 +v++++kd+ +++CyY FUN_001088-T1 327 GVHRDEKDHMFFLCYY 342 ***************9 PP >> DUF6753 Family of unknown function (DUF6753) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 1.8e-05 0.22 85 142 .. 405 462 .. 380 489 .. 0.79 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 1.8e-05 DUF6753 85 erqkvaiakaakelirkaeakelrrllksllPalavllavlglGfilGitvpvllqgg 142 +++++ ++ k +i++ ++ e+ +++++++ +++++l ++ lG+++G+ v+ ++ + FUN_001088-T1 405 HNKETNKNERTKTIIKTIRVPEHENTTSIVVTTAGIVLGIVVLGAVVGVVVTKRMRTN 462 5566667788999***************************************999432 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (539 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2680 (0.104913); expected 510.9 (0.02) Passed bias filter: 1128 (0.0441574); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.42s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 5155.06 // Query: FUN_001089-T1 [L=304] Description: FUN_001089 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-50 169.9 3.1 1.5e-49 169.2 3.1 1.4 1 ApeC C-terminal domain of apextrin Domain annotation for each model (and alignments): >> ApeC C-terminal domain of apextrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 169.2 3.1 5.9e-54 1.5e-49 1 208 [] 22 218 .. 22 218 .. 0.92 Alignments for each domain: == domain 1 score: 169.2 bits; conditional E-value: 5.9e-54 ApeC 1 WPaGsYGlPkpvsgCpesegveWktGvrfqdtedddek.skksaslhlagsvskegvkqefCikkdtkgeeerpeWpeGkYCiykkgdeCPaglee 95 WP G+Y lP+p +gCp++ W +G rf+dt + ++ +slhlag +skeg++q fCik+++ ++++ WpeGkYCi+k++ CP+g+++ FUN_001089-T1 22 WPPGQYALPMPKAGCPDN----WFEGRRFHDTSGTLLIdQNIYESLHLAGWISKEGIEQDFCIKTTPVKDSS-HGWPEGKYCILKQEY-CPTGFST 111 ****************85....**********9776541556799*********************999998.89**********995.******* PP ApeC 96 GyirwdDensevdnenkesGtlPeGvYdentliefCCstkGskdtaikLPldspfyLlayesasCqkvkgakvteeflkfddedeenkdaeggahP 191 G + w ++s ++ +G+Y +nt+i++CC+ +G++++ai LPld+pfyL++++ +sCq+v+ga+v+ee ++ ++++ +++ +++g P FUN_001089-T1 112 GSVSWRPSSSPF--QDL----SVNGKYLKNTTISYCCRMRGDTKQAILLPLDKPFYLYTLRGTSCQNVRGATVKEESVSLENTHGKYEIDMKGVNP 201 *****9987733..333....3479*******************************************************9999999999****** PP ApeC 192 ylvtkkkkdltlyyCyY 208 + + ++ ++ yCyY FUN_001089-T1 202 FITDGNNSPAKITYCYY 218 **999999********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (304 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 725 (0.0283813); expected 510.9 (0.02) Passed bias filter: 606 (0.0237228); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.43s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 2933.03 // Query: FUN_001090-T1 [L=472] Description: FUN_001090 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (472 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 799 (0.0312781); expected 510.9 (0.02) Passed bias filter: 540 (0.0211392); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4532.17 // Query: FUN_001091-T1 [L=118] Description: FUN_001091 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0004 21.5 0.1 0.00052 21.1 0.1 1.1 1 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family ------ inclusion threshold ------ 0.025 15.2 1.1 0.057 14.0 1.1 1.5 1 Lipase_GDSL GDSL-like Lipase/Acylhydrolase 0.044 13.7 0.7 0.095 12.6 0.4 1.7 2 P3A Poliovirus 3A protein like 0.15 12.5 0.0 0.26 11.6 0.0 1.4 1 CofH_C CofH/MqnC C-terminal region Domain annotation for each model (and alignments): >> Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.1 8.1e-08 0.00052 60 177 .. 10 111 .. 3 112 .. 0.71 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 8.1e-08 Lipase_GDSL_2 60 rlkpdlvvillGtNDlgrgvpparaaannlealvrrlraaapgarvlglgplpvgpppppdarrlnarlaalneairevaaeegvpfvdladalad 155 + kp+ +++++GtNDl+ +++p+ +a+n + l +++ +a v+ + ++ +n+ ++a+n+ + +++ ++++ + ++ FUN_001091-T1 10 DKKPQQIILHVGTNDLR-DHSPTVVAEN-IVDLAKKIEME-SNAEVI------LSELVSRSDNVSNDAVKAVNKRLIKYCNQNDWRMIKHQNID-- 94 578999*********85.5555555666.77777777766.788888......34444444455688899**************9999883222.. PP Lipase_GDSL_2 156 ddgrlpdlladdglHPnaaGyr 177 ++ l glH+n++ ++ FUN_001091-T1 95 -----RNCLNKSGLHLNEKDHQ 111 .....22334445999998776 PP >> Lipase_GDSL GDSL-like Lipase/Acylhydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 1.1 8.9e-06 0.057 74 202 .. 10 111 .. 3 115 .. 0.70 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 8.9e-06 Lipase_GDSL 74 qakpdlvtieiGaNDllnalssparskkrleelldelranlpelgarkflvhglgplgctpekceelynalaeeynerlnelvnslaaaaedanvv 169 +kp+ +++ +G+NDl + s + + e++ +l +++++ ++ v + + ++ n++++ n+rl +++n+ + ++ FUN_001091-T1 10 DKKPQQIILHVGTNDLR------DHSPTVVAENIVDLAKKIEM--ESNAEVILSELVSR----SDNVSNDAVKAVNKRLIKYCNQNDWR----MIK 89 6899***********94......46777777777777777777..33333333344433....34778999999999999999976666....666 PP Lipase_GDSL 170 lvdiygfedptkpccgigsefwDglHpsekgyk 202 +i ++c + + glH++ek ++ FUN_001091-T1 90 HQNI------DRNCLN-----KSGLHLNEKDHQ 111 6666......444444.....367888888887 PP >> P3A Poliovirus 3A protein like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 0.45 2.9e+03 19 27 .. 35 43 .. 21 52 .. 0.57 2 ? 12.6 0.4 1.5e-05 0.095 22 55 .. 66 96 .. 58 100 .. 0.76 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.45 P3A 19 eaiaDLLra 27 e i DL + FUN_001091-T1 35 ENIVDLAKK 43 344444443 PP == domain 2 score: 12.6 bits; conditional E-value: 1.5e-05 P3A 22 aDLLravdsqEvidYCedknWivnitaevsiERd 55 +D ++av+ +i+YC++++W + i + +i+R+ FUN_001091-T1 66 NDAVKAVNK-RLIKYCNQNDWRM-IK-HQNIDRN 96 888999975.689********87.43.4456665 PP >> CofH_C CofH/MqnC C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 4.1e-05 0.26 57 87 .. 8 41 .. 4 58 .. 0.80 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.1e-05 CofH_C 57 tvgkkvaqiclhagandf...gsimieenvvsaa 87 tv kk qi+lh g+nd+ ++ en+v a FUN_001091-T1 8 TVDKKPQQIILHVGTNDLrdhSPTVVAENIVDLA 41 899*************972224578999999765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (118 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1278 (0.0500294); expected 510.9 (0.02) Passed bias filter: 649 (0.0254061); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1171.04 // Query: FUN_001091-T2 [L=112] Description: FUN_001091 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-05 26.2 0.0 2e-05 25.7 0.0 1.1 1 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family 0.005 17.5 0.6 0.012 16.2 0.6 1.6 1 Lipase_GDSL GDSL-like Lipase/Acylhydrolase ------ inclusion threshold ------ 0.039 13.8 0.7 0.086 12.7 0.4 1.7 2 P3A Poliovirus 3A protein like 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 CofH_C CofH/MqnC C-terminal region Domain annotation for each model (and alignments): >> Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 3.2e-09 2e-05 60 176 .. 10 110 .. 3 111 .. 0.73 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 3.2e-09 Lipase_GDSL_2 60 rlkpdlvvillGtNDlgrgvpparaaannlealvrrlraaapgarvlglgplpvgpppppdarrlnarlaalneairevaaeegvpfvdladalad 155 + kp+ +++++GtNDl+ +++p+ +a+n + l +++ +a v+ + ++ +n+ ++a+n+ + +++ ++++ + ++ FUN_001091-T2 10 DKKPQQIILHVGTNDLR-DHSPTVVAEN-IVDLAKKIEME-SNAEVI------LSELVSRSDNVSNDAVKAVNKRLIKYCNQNDWRMIKHQNID-- 94 578999*********85.5555555666.77777777766.788888......3444444445568889****************999883222.. PP Lipase_GDSL_2 156 ddgrlpdlladdglHPnaaGy 176 ++ l glH+n++Gy FUN_001091-T2 95 -----RNCLNKSGLHLNEKGY 110 .....23344446*******9 PP >> Lipase_GDSL GDSL-like Lipase/Acylhydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.6 1.9e-06 0.012 74 201 .. 10 110 .. 3 112 .] 0.72 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.9e-06 Lipase_GDSL 74 qakpdlvtieiGaNDllnalssparskkrleelldelranlpelgarkflvhglgplgctpekceelynalaeeynerlnelvnslaaaaedanvv 169 +kp+ +++ +G+NDl + s + + e++ +l +++++ ++ v + + ++ n++++ n+rl +++n+ + ++ FUN_001091-T2 10 DKKPQQIILHVGTNDLR------DHSPTVVAENIVDLAKKIEM--ESNAEVILSELVSR----SDNVSNDAVKAVNKRLIKYCNQNDWR----MIK 89 6899***********94......56777777777788888777..33333444444433....3477899***********99977666....777 PP Lipase_GDSL 170 lvdiygfedptkpccgigsefwDglHpsekgy 201 +i ++c + + glH++ekgy FUN_001091-T2 90 HQNI------DRNCLN-----KSGLHLNEKGY 110 6666......555555.....46899999999 PP >> P3A Poliovirus 3A protein like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 0.41 2.6e+03 19 27 .. 35 43 .. 21 52 .. 0.57 2 ? 12.7 0.4 1.4e-05 0.086 22 55 .. 66 96 .. 58 100 .. 0.76 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.41 P3A 19 eaiaDLLra 27 e i DL + FUN_001091-T2 35 ENIVDLAKK 43 344444443 PP == domain 2 score: 12.7 bits; conditional E-value: 1.4e-05 P3A 22 aDLLravdsqEvidYCedknWivnitaevsiERd 55 +D ++av+ +i+YC++++W + i + +i+R+ FUN_001091-T2 66 NDAVKAVNK-RLIKYCNQNDWRM-IK-HQNIDRN 96 888999975.689********87.43.4456665 PP >> CofH_C CofH/MqnC C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 3.7e-05 0.24 57 87 .. 8 41 .. 4 57 .. 0.80 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 3.7e-05 CofH_C 57 tvgkkvaqiclhagandf...gsimieenvvsaa 87 tv kk qi+lh g+nd+ ++ en+v a FUN_001091-T2 8 TVDKKPQQIILHVGTNDLrdhSPTVVAENIVDLA 41 899*************972224578999999765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (112 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1169 (0.0457624); expected 510.9 (0.02) Passed bias filter: 648 (0.025367); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1106.68 // Query: FUN_001092-T1 [L=108] Description: FUN_001092 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (108 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 620 (0.0242709); expected 510.9 (0.02) Passed bias filter: 423 (0.016559); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.35s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1105.88 // Query: FUN_001093-T1 [L=262] Description: FUN_001093 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00043 19.9 0.2 0.00056 19.6 0.2 1.1 1 DUF6492 Family of unknown function (DUF6492) ------ inclusion threshold ------ 0.15 12.3 0.0 0.22 11.7 0.0 1.3 1 RapZ-like_N RapZ-like N-terminal domain Domain annotation for each model (and alignments): >> DUF6492 Family of unknown function (DUF6492) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.2 4.4e-08 0.00056 27 211 .. 63 249 .. 58 260 .. 0.72 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 4.4e-08 DUF6492 27 Lfkslrkfakpellhkflivvpdeeveevkelakawsd.fdievideselvpefskrkqvrgWhrqqi.iKlaaaarieteffl.vlDaDviclrp 119 Lf+s++ f ++ ++++v ++e+ + + ++ + + + + + e + + W + ++ + + a++ ++ ++ ++D D +++ FUN_001093-T1 63 LFRSIKIFWPKN--TRVVVVLDKENTGDTAYGS-TIMEtTLSKHMALNVCFMEAYPSEMIHHWGKMRMyVDMMHADLCTNATYVgLVDVDTLFITA 155 666666666552..2344444444444433222.23331222223333455566677789999887654899999999999998678********* PP DUF6492 120 fdledlipdgkallvie.arsahpkwweaaaklLkvdpnsdriglgvtPavlskqlvkelkerlealkgrdWrrvLlsnk...kvdwtEYtLYyla 211 ++ ++ gk ++ + ++ p w ++++ +L++++ + + + P++++++ +ke ++++++l+g+d+ +v+ kvd Y Y ++ FUN_001093-T1 156 VTPSVVLEAGKPVVTGRiGEPRIPCWMKTSEYVLGIKQVM--QCMHYFPVTFKTAHIKEFRDYVTKLHGKDFNDVIAEASnksKVDSNCYCHYSMM 249 ***********98765427889999************998..88999*************************999976544455555555555544 PP >> RapZ-like_N RapZ-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 1.8e-05 0.22 49 104 .. 72 127 .. 39 143 .. 0.86 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 1.8e-05 RapZ-like_N 49 sreskvavvlDvrnreesaelleqalellekaitprilfleadddtLvrrysdtrr 104 ++++v vvlD n +++a ++ +l+k++ ++ f+ea + +++ + + r FUN_001093-T1 72 PKNTRVVVVLDKENTGDTAYGSTIMETTLSKHMALNVCFMEAYPSEMIHHWGKMRM 127 57899**************************************9999999887775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (262 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 928 (0.036328); expected 510.9 (0.02) Passed bias filter: 592 (0.0231748); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2532.08 // Query: FUN_001094-T1 [L=214] Description: FUN_001094 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-12 46.6 7.0 4.5e-12 46.1 7.0 1.2 1 KIAA0319_N Dyslexia-associated protein KIAA0319 N-terminal d 8e-07 29.7 8.4 1.4e-06 28.9 8.4 1.4 1 MANEC MANEC domain ------ inclusion threshold ------ 0.023 15.0 8.4 0.053 13.8 8.4 1.6 1 PAN_3 PAN-like domain Domain annotation for each model (and alignments): >> KIAA0319_N Dyslexia-associated protein KIAA0319 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.1 7.0 5.2e-16 4.5e-12 3 84 .. 33 117 .. 31 118 .. 0.86 Alignments for each domain: == domain 1 score: 46.1 bits; conditional E-value: 5.2e-16 KIAA0319_N 3 kCqegkvlfgaglrseeet.hlqllegshsvqsCqaaCCqspsCdafWlleemCilvnCskpesCeakrtdss..ksllvflkrs 84 C++++v +++l+ ++ + ++ + +C CC+s+ Cd++ ++++ C+lv+C++++sCe k+ d+s + +l ++++s FUN_001094-T1 33 PCRKSSVNYNVTLSRGAKAgKYYKISSIDNMDDCVSNCCRSKRCDVAFMVNKNCYLVKCHNSDSCELKQSDNSkfDTMLSVVSKS 117 7***********99976643788899999*************************************9998865225788887776 PP >> MANEC MANEC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.9 8.4 1.7e-10 1.4e-06 21 85 .. 45 103 .. 33 107 .. 0.79 Alignments for each domain: == domain 1 score: 28.9 bits; conditional E-value: 1.7e-10 MANEC 21 vkeGak...flesaevsseedCvraCCkekkCnlalleekkeeekkksCyLfnClyeskfvCkfakkk 85 +++Gak + + ++++ +dCv+ CC++k+C++a++ +k+ CyL++C ++++ C++++++ FUN_001094-T1 45 LSRGAKagkYYKISSIDNMDDCVSNCCRSKRCDVAFMVNKN-------CYLVKC--HNSDSCELKQSD 103 55555411145566788999*****************9988.......******..89999*999876 PP >> PAN_3 PAN-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 8.4 6.2e-06 0.053 17 63 .. 58 104 .. 48 110 .. 0.83 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 6.2e-06 PAN_3 17 ttseswdeCvtkCledetCvlayknsenCqlfeignvstvkkiesss 63 +++++d+Cv++C + C +a+ ++nC+l + n ++ + +s++ FUN_001094-T1 58 SSIDNMDDCVSNCCRSKRCDVAFMVNKNCYLVKCHNSDSCELKQSDN 104 56799**************************9999988866444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (214 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1094 (0.0428264); expected 510.9 (0.02) Passed bias filter: 477 (0.0186729); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2089.10 // Query: FUN_001095-T1 [L=121] Description: FUN_001095 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.047 13.6 0.3 0.058 13.3 0.3 1.1 1 DUF4300 Domain of unknown function (DUF4300) Domain annotation for each model (and alignments): >> DUF4300 Domain of unknown function (DUF4300) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.3 2.3e-06 0.058 151 209 .. 16 70 .. 4 80 .. 0.82 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.3e-06 DUF4300 151 ekikeewkerkikFkekkislisvflhsaldesslFvgHvgvlvkakdgkllfiEKlsf 209 +k+ + ++ + F++ +++++s +++s s Fv+Hv vl + + ++f+ K++ FUN_001095-T1 16 AKLSMQTSDLRLDFSNVNVQIVSHLFES----SFAFVSHVVVLFVDIPQAIFFFKKIDQ 70 5666777888999*************99....566********9988899999999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 646 (0.0252887); expected 510.9 (0.02) Passed bias filter: 418 (0.0163633); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1222.19 // Query: FUN_001096-T1 [L=322] Description: FUN_001096 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-18 65.0 12.6 8.2e-11 42.0 2.8 3.4 3 KIAA0319_N Dyslexia-associated protein KIAA0319 N-termin 0.00013 22.6 14.4 0.001 19.8 2.3 3.1 3 MANEC MANEC domain 0.00043 20.8 22.8 0.12 13.0 9.6 3.5 2 EGF_Teneurin Teneurin-like EGF domain 0.00052 20.2 31.6 0.00052 20.2 31.6 2.6 2 EGF_TEN Teneurin EGF domain ------ inclusion threshold ------ 0.032 14.8 1.5 0.032 14.8 1.5 3.1 3 EGF_DL_JAG Delta-like/Jagged, EGF-like domain 0.14 12.7 14.7 0.93 10.1 1.9 3.3 2 JAG1-like_EGF2 Protein jagged-1-like, atypical EGF2 0.72 10.2 17.1 1.1 9.6 3.7 3.5 3 TSP1_TSH7A-B_C THS7A/B C-terminal TSP1 domain 1.9 8.8 29.1 0.051 13.9 5.0 3.8 4 PAN_3 PAN-like domain Domain annotation for each model (and alignments): >> KIAA0319_N Dyslexia-associated protein KIAA0319 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 2.4 2.1e-12 6.7e-09 4 68 .. 46 111 .. 44 120 .. 0.78 2 ! 42.0 2.8 2.6e-14 8.2e-11 2 74 .. 158 231 .. 157 244 .. 0.88 3 ? -7.9 8.2 8 2.6e+04 51 71 .. 285 305 .. 254 311 .. 0.70 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 2.1e-12 KIAA0319_N 4 Cqegkvlfgaglrse.eethlqllegshsvqsCqaaCCqspsCdafWlleemCilvnCskpesCea 68 C + + ++++lr ++ + l + +q+C aCCq+++Cd++ + +++C+ v+C + + Ce FUN_001096-T1 46 CTHLDIKHDVTLRGGiKSGNFTKLGYLRDMQTCIDACCQDEKCDVAFMPGHVCYSVSCFSAKLCES 111 5555555566666541233455666677899*********************************96 PP == domain 2 score: 42.0 bits; conditional E-value: 2.6e-14 KIAA0319_N 2 skCqegkvlfgaglrseeet.hlqllegshsvqsCqaaCCqspsCdafWlleemCilvnCskpesCeakrtdss 74 ++C +++++++ +l+ ++ ++ l +s+++C CC++++C+++ l+++ C v+C e C+ ++++ FUN_001096-T1 158 DQCTPSRIVTNHTLKGGKTAgEIKDLGMVESIENCIEKCCDEKACEVAFLVDGKCHSVECYGDELCQSLPIENE 231 79*************9876538*********************************************8776654 PP == domain 3 score: -7.9 bits; conditional E-value: 8 KIAA0319_N 51 leemCilvnCskpesCeakrt 71 + + C + C ++C+ ++t FUN_001096-T1 285 ITGYCGISGCGAYGKCSSNDT 305 345677777777777776665 PP >> MANEC MANEC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 2.3 3.2e-07 0.001 27 72 .. 66 104 .. 47 114 .. 0.76 2 ! 15.9 4.5 5.1e-06 0.016 30 67 .. 183 218 .. 152 229 .. 0.75 3 ? -3.8 1.9 7.1 2.3e+04 32 45 .. 247 260 .. 240 281 .. 0.68 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 3.2e-07 MANEC 27 flesaevsseedCvraCCkekkCnlalleekkeeekkksCyLfnCl 72 f++ ++++ + C+ aCC+++kC++a++ + Cy ++C FUN_001096-T1 66 FTKLGYLRDMQTCIDACCQDEKCDVAFMPGHV-------CYSVSCF 104 55566789999****************98766.......7777773 PP == domain 2 score: 15.9 bits; conditional E-value: 5.1e-06 MANEC 30 saevsseedCvraCCkekkCnlalleekkeeekkksCy 67 v+s e+C++ CC+ek+C++a+l k ++ +Cy FUN_001096-T1 183 LGMVESIENCIEKCCDEKACEVAFLVDGK--CHSVECY 218 4568999****************998877..4455554 PP == domain 3 score: -3.8 bits; conditional E-value: 7.1 MANEC 32 evsseedCvraCCk 45 +++++e C + C + FUN_001096-T1 247 RIKDKETCSSPCIS 260 45666777777654 PP >> EGF_Teneurin Teneurin-like EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 5.3 9.2e-05 0.29 8 29 .. 260 282 .. 250 283 .. 0.84 2 ! 13.0 9.6 3.6e-05 0.12 5 29 .. 294 319 .. 292 320 .. 0.94 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 9.2e-05 EGF_Teneurin 8 hGtC.kkGsCaCesGWkGeeCdv 29 G+C k+ C+C+ G+ G Cd FUN_001096-T1 260 SGVCaAKDICVCDRGFEGLNCDH 282 499*99999************95 PP == domain 2 score: 13.0 bits; conditional E-value: 3.6e-05 EGF_Teneurin 5 CgghGtC.kkGsCaCesGWkGeeCdv 29 Cg G C + ++C+Ce G+ G C++ FUN_001096-T1 294 CGAYGKCsSNDTCVCETGYFGHLCNQ 319 9******9999*************98 PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 6.3 0.59 1.9e+03 88 157 .. 76 147 .. 45 179 .. 0.55 2 ! 20.2 31.6 1.6e-07 0.00052 88 221 .. 190 319 .. 184 321 .. 0.74 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.59 EGF_TEN 88 kkCeektcldanCsgngvCvngkCvCeegytgedCelek...kackekcskkgklvkesgscvcdegytgedc 157 ++C c+d++C C+ + ++++ Ce++ ++ ++ + +++v g++ e+++ ++ FUN_001096-T1 76 QTCIDACCQDEKCDVA-FMPGHVCYSVSCFSAKLCESIPavpSIAANRSVRISHVVRGGGKGDDLEQFKKTQG 147 3455555555555433.22345677777777888877541112222333333344444444444444544444 PP == domain 2 score: 20.2 bits; conditional E-value: 1.6e-07 EGF_TEN 88 kkCeektcldanCsgngvCvngkCvCeegytgedCelekkackekcskkgklvkesgscvcdegytgedceeetcsldCgehgkCve.skCkCdeg 182 ++C ek c ++ C+ v+gkC e y e C++ + +e++s + +++e+ ++ + + ++etcs+ C g C+ + C+Cd+g FUN_001096-T1 190 ENCIEKCCDEKACE-VAFLVDGKCHSVECYGDELCQSL-PIENEQISPTIVYMNER-NG-----V--RIKDKETCSSPC-ISGVCAAkDICVCDRG 274 57999989888885.567899*********9999*985.44556666655554322.22.....2..2346778*****.7788876368****** PP EGF_TEN 183 wtGekCekk....tCe.srCkehGvck.nGtCiCekGfngeecsl 221 ++G +C+++ C s C + G c+ n tC+Ce+G+ g+ c++ FUN_001096-T1 275 FEGLNCDHTaitgYCGiSGCGAYGKCSsNDTCVCETGYFGHLCNQ 319 *******88333345424688999996379*************86 PP >> EGF_DL_JAG Delta-like/Jagged, EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.2 0.4 8 2.6e+04 4 8 .. 253 257 .. 253 257 .. 0.86 2 ? 7.2 0.9 0.0024 7.6 11 24 .. 269 282 .. 259 283 .. 0.86 3 ? 14.8 1.5 1e-05 0.032 3 24 .. 298 319 .. 296 320 .. 0.92 Alignments for each domain: == domain 1 score: -4.2 bits; conditional E-value: 8 EGF_DL_JAG 4 tCskP 8 tCs P FUN_001096-T1 253 TCSSP 257 89998 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0024 EGF_DL_JAG 11 CnCeeGWgGlfCdq 24 C+C+ G Gl Cd FUN_001096-T1 269 CVCDRGFEGLNCDH 282 ************95 PP == domain 3 score: 14.8 bits; conditional E-value: 1e-05 EGF_DL_JAG 3 GtCskPweCnCeeGWgGlfCdq 24 G Cs +C+Ce G G +C+q FUN_001096-T1 298 GKCSSNDTCVCETGYFGHLCNQ 319 8999999**************9 PP >> JAG1-like_EGF2 Protein jagged-1-like, atypical EGF2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 5.3 0.0043 14 3 23 .. 261 281 .. 253 282 .. 0.83 2 ? 10.1 1.9 0.00029 0.93 3 24 .. 298 319 .. 296 320 .. 0.94 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0043 JAG1-like_EGF2 3 GtCkepwqCtCdEGwgGlFCD 23 G C C Cd G+ Gl CD FUN_001096-T1 261 GVCAAKDICVCDRGFEGLNCD 281 55666689************9 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00029 JAG1-like_EGF2 3 GtCkepwqCtCdEGwgGlFCDq 24 G+C+ C C+ G+ G C q FUN_001096-T1 298 GKCSSNDTCVCETGYFGHLCNQ 319 99******************87 PP >> TSP1_TSH7A-B_C THS7A/B C-terminal TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 2.5 7.9e+03 33 37 .. 158 162 .. 149 163 .. 0.78 2 ? 5.9 3.6 0.0051 16 9 22 .. 262 275 .. 253 277 .. 0.89 3 ? 9.6 3.7 0.00034 1.1 10 22 .. 300 312 .. 297 314 .. 0.95 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 2.5 TSP1_TSH7A-B_C 33 dqCtk 37 dqCt+ FUN_001096-T1 158 DQCTP 162 89997 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0051 TSP1_TSH7A-B_C 9 yCteagvCgCeeGY 22 C + +C+C++G+ FUN_001096-T1 262 VCAAKDICVCDRGF 275 699**********9 PP == domain 3 score: 9.6 bits; conditional E-value: 0.00034 TSP1_TSH7A-B_C 10 CteagvCgCeeGY 22 C+++ +C+Ce GY FUN_001096-T1 300 CSSNDTCVCETGY 312 ************* PP >> PAN_3 PAN-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 1.8 6.4e-05 0.21 5 46 .. 58 99 .. 55 106 .. 0.84 2 ? 13.9 5.0 1.6e-05 0.051 17 46 .. 184 213 .. 174 223 .. 0.89 3 ? -2.1 0.4 1.6 5.2e+03 17 31 .. 246 260 .. 235 270 .. 0.69 4 ? -1.9 1.4 1.3 4.2e+03 28 36 .. 299 307 .. 297 310 .. 0.89 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 6.4e-05 PAN_3 5 yGepedlisteettseswdeCvtkCledetCvlayknsenCq 46 +G + + + t+ ++++C++ C +de+C +a+ C+ FUN_001096-T1 58 RGGIKSGNFTKLGYLRDMQTCIDACCQDEKCDVAFMPGHVCY 99 566667777888888999*****************9998987 PP == domain 2 score: 13.9 bits; conditional E-value: 1.6e-05 PAN_3 17 ttseswdeCvtkCledetCvlayknsenCq 46 ++es ++C++kC ++ C +a+ +++C+ FUN_001096-T1 184 GMVESIENCIEKCCDEKACEVAFLVDGKCH 213 5789*************************8 PP == domain 3 score: -2.1 bits; conditional E-value: 1.6 PAN_3 17 ttseswdeCvtkCle 31 +++ ++C + C + FUN_001096-T1 246 VRIKDKETCSSPCIS 260 556777778777765 PP == domain 4 score: -1.9 bits; conditional E-value: 1.3 PAN_3 28 kCledetCv 36 kC +++tCv FUN_001096-T1 299 KCSSNDTCV 307 8*******8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (322 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 938 (0.0367195); expected 510.9 (0.02) Passed bias filter: 406 (0.0158935); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 3262.24 // Query: FUN_001096-T2 [L=435] Description: FUN_001096 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-17 63.2 12.6 1.4e-10 41.3 2.8 3.6 4 KIAA0319_N Dyslexia-associated protein KIAA0319 N-termin 9.3e-07 29.3 18.3 0.013 16.0 1.0 4.4 3 EGF_DL_JAG Delta-like/Jagged, EGF-like domain 1.1e-05 25.9 40.0 0.1 13.1 9.1 4.3 3 EGF_Teneurin Teneurin-like EGF domain 0.0001 22.5 23.0 0.0001 22.5 23.0 3.4 3 EGF_TEN Teneurin EGF domain 0.00026 21.7 23.3 0.0016 19.2 2.3 3.2 3 MANEC MANEC domain 0.0011 19.7 7.4 0.0011 19.7 7.4 4.6 4 EGF EGF-like domain ------ inclusion threshold ------ 0.44 11.1 2.8 0.92 10.1 2.8 1.5 1 PGF-CTERM PGF-CTERM motif 1.4 9.5 31.0 1 9.9 2.5 4.4 4 JAG1-like_EGF2 Protein jagged-1-like, atypical EGF2 Domain annotation for each model (and alignments): >> KIAA0319_N Dyslexia-associated protein KIAA0319 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.2 2.4 3.4e-12 1.1e-08 6 68 .. 48 111 .. 44 120 .. 0.77 2 ! 41.3 2.8 4.3e-14 1.4e-10 2 74 .. 158 231 .. 157 244 .. 0.88 3 ? -7.2 7.0 8 2.6e+04 51 71 .. 285 305 .. 254 311 .. 0.70 4 ? -6.0 5.4 8 2.6e+04 55 71 .. 289 305 .. 283 344 .. 0.65 Alignments for each domain: == domain 1 score: 35.2 bits; conditional E-value: 3.4e-12 KIAA0319_N 6 egkvlfgaglrse.eethlqllegshsvqsCqaaCCqspsCdafWlleemCilvnCskpesCea 68 + + ++++lr ++ + l + +q+C aCCq+++Cd++ + +++C+ v+C + + Ce FUN_001096-T2 48 HLDIKHDVTLRGGiKSGNFTKLGYLRDMQTCIDACCQDEKCDVAFMPGHVCYSVSCFSAKLCES 111 55555555565541233455566677899*********************************96 PP == domain 2 score: 41.3 bits; conditional E-value: 4.3e-14 KIAA0319_N 2 skCqegkvlfgaglrseeet.hlqllegshsvqsCqaaCCqspsCdafWlleemCilvnCskpesCeakrtdss 74 ++C +++++++ +l+ ++ ++ l +s+++C CC++++C+++ l+++ C v+C e C+ ++++ FUN_001096-T2 158 DQCTPSRIVTNHTLKGGKTAgEIKDLGMVESIENCIEKCCDEKACEVAFLVDGKCHSVECYGDELCQSLPIENE 231 79*************9876538*********************************************8776644 PP == domain 3 score: -7.2 bits; conditional E-value: 8 KIAA0319_N 51 leemCilvnCskpesCeakrt 71 + + C + C ++C+ ++t FUN_001096-T2 285 ITGYCGISGCGAYGKCSSNDT 305 345677777777777776655 PP == domain 4 score: -6.0 bits; conditional E-value: 8 KIAA0319_N 55 CilvnCskpesCeakrt 71 C + C ++C+ ++t FUN_001096-T2 289 CGISGCGAYGKCSSNDT 305 55555555555555444 PP >> EGF_DL_JAG Delta-like/Jagged, EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.9 0.0034 11 11 24 .. 269 282 .. 259 283 .. 0.86 2 ! 16.0 1.0 4e-06 0.013 3 26 .] 298 321 .. 296 321 .. 0.92 3 ! 14.6 2.7 1.1e-05 0.035 10 24 .. 341 355 .. 338 356 .. 0.93 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0034 EGF_DL_JAG 11 CnCeeGWgGlfCdq 24 C+C+ G Gl Cd FUN_001096-T2 269 CVCDRGFEGLNCDH 282 ************95 PP == domain 2 score: 16.0 bits; conditional E-value: 4e-06 EGF_DL_JAG 3 GtCskPweCnCeeGWgGlfCdqdl 26 G Cs +C+Ce G G +C+q l FUN_001096-T2 298 GKCSSNDTCVCETGYFGHLCNQTL 321 8999999**************976 PP == domain 3 score: 14.6 bits; conditional E-value: 1.1e-05 EGF_DL_JAG 10 eCnCeeGWgGlfCdq 24 +C Ce GW G fC++ FUN_001096-T2 341 KCFCEIGWEGQFCNK 355 5*************8 PP >> EGF_Teneurin Teneurin-like EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.1 5.4 0.00014 0.46 8 28 .. 260 281 .. 251 283 .. 0.83 2 ! 12.5 9.6 5.3e-05 0.17 5 29 .. 294 319 .. 292 320 .. 0.94 3 ! 13.1 9.1 3.3e-05 0.1 1 29 [. 323 355 .. 323 356 .. 0.89 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00014 EGF_Teneurin 8 hGtC.kkGsCaCesGWkGeeCd 28 G+C k+ C+C+ G+ G Cd FUN_001096-T2 260 SGVCaAKDICVCDRGFEGLNCD 281 399*99999************9 PP == domain 2 score: 12.5 bits; conditional E-value: 5.3e-05 EGF_Teneurin 5 CgghGtC.kkGsCaCesGWkGeeCdv 29 Cg G C + ++C+Ce G+ G C++ FUN_001096-T2 294 CGAYGKCsSNDTCVCETGYFGHLCNQ 319 9******9999*************98 PP == domain 3 score: 13.1 bits; conditional E-value: 3.3e-05 EGF_Teneurin 1 CppqCgghGtCkkGs.....CaCesGWkGeeCdv 29 C p C ++G+C++ s C Ce GW G C+ FUN_001096-T2 323 CNPPC-ENGRCIDNStnstkCFCEIGWEGQFCNK 355 77777.8****999999999************97 PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -12.0 21.5 8 2.6e+04 120 216 .. 158 220 .. 58 224 .. 0.36 2 ! 10.5 26.9 0.00014 0.45 88 209 .. 190 301 .. 155 302 .. 0.79 3 ! 22.5 23.0 3.3e-08 0.0001 164 222 .. 292 356 .. 286 361 .. 0.81 Alignments for each domain: == domain 1 score: -12.0 bits; conditional E-value: 8 EGF_TEN 120 edCelekkackekcskkgklvkesgscvcdegytgedceeetcsldCgehgkCveskCkCdegwtGekCekktCesrCkehGvc.....knGtCiC 210 ++C+ ++ ++ + + +k + + + G + ++C ++C ++ c ++G+C FUN_001096-T2 158 DQCT---------------------------------------PSRIVTNHTLKGGKTAGEIKDLGMVESIENCIEKCCDEKACevaflVDGKCHS 214 1222.......................................22222222222233333333333222222333333332222111114555555 PP EGF_TEN 211 ekGfng 216 + + FUN_001096-T2 215 VECYGD 220 444444 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00014 EGF_TEN 88 kkCeektcldanCsgngvCvngkCvCeegytgedCelekkackekcskkgklvkesgscvcdegytgedceeetcsldCgehgkCve.skCkCdeg 182 ++C ek c ++ C+ v+gkC e y e C++ + +e++s + +++e+ ++ + + ++etcs+ C g C+ + C+Cd+g FUN_001096-T2 190 ENCIEKCCDEKACE-VAFLVDGKCHSVECYGDELCQSL-PIENEQISPTIVYMNER-NG-----V--RIKDKETCSSPC-ISGVCAAkDICVCDRG 274 67888888888885.56789999*99999999999985.44556666655554322.22.....2..2346778*****.7788876368****** PP EGF_TEN 183 wtGekCekktCesrCkehGvcknGtCi 209 ++G +C++++ + C G+ G+C FUN_001096-T2 275 FEGLNCDHTAITGYCGISGCGAYGKCS 301 *************************96 PP == domain 3 score: 22.5 bits; conditional E-value: 3.3e-08 EGF_TEN 164 ldCgehgkCve.skCkCdegwtGekCekk.tCesrCkehGvckn.....GtCiCekGfngeecsle 222 + Cg+ gkC++ ++C+C++g+ G+ C+++ tC+ C+ +G+c + +C Ce G++g+ c+ + FUN_001096-T2 292 SGCGAYGKCSSnDTCVCETGYFGHLCNQTlTCNPPCE-NGRCIDnstnsTKCFCEIGWEGQFCNKA 356 46*******98469************97669*****7.6999653333357************875 PP >> MANEC MANEC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 2.3 5e-07 0.0016 27 72 .. 66 104 .. 47 114 .. 0.76 2 ! 15.3 4.5 8.1e-06 0.026 30 67 .. 183 218 .. 153 228 .. 0.75 3 ? -4.3 1.5 8 2.6e+04 33 45 .. 248 260 .. 242 274 .. 0.64 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 5e-07 MANEC 27 flesaevsseedCvraCCkekkCnlalleekkeeekkksCyLfnCl 72 f++ ++++ + C+ aCC+++kC++a++ + Cy ++C FUN_001096-T2 66 FTKLGYLRDMQTCIDACCQDEKCDVAFMPGHV-------CYSVSCF 104 55566789999****************98766.......7777773 PP == domain 2 score: 15.3 bits; conditional E-value: 8.1e-06 MANEC 30 saevsseedCvraCCkekkCnlalleekkeeekkksCy 67 v+s e+C++ CC+ek+C++a+l k ++ +Cy FUN_001096-T2 183 LGMVESIENCIEKCCDEKACEVAFLVDGK--CHSVECY 218 4568999****************998877..4455555 PP == domain 3 score: -4.3 bits; conditional E-value: 8 MANEC 33 vsseedCvraCCk 45 ++++e C + C + FUN_001096-T2 248 IKDKETCSSPCIS 260 5666677776654 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.5 1.8 5.9e+03 1 16 [. 212 227 .. 210 231 .. 0.78 2 ! 6.8 2.5 0.0037 12 1 31 [. 254 278 .. 254 279 .. 0.86 3 ? 4.1 9.2 0.026 82 1 31 [. 289 315 .. 289 316 .. 0.85 4 ! 19.7 7.4 3.4e-07 0.0011 1 31 [. 323 351 .. 322 352 .. 0.90 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.8 EGF 1 CspnpCsngGtCvdtp 16 C++ C ++ C ++p FUN_001096-T2 212 CHSVECYGDELCQSLP 227 7877788888887776 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0037 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 Cs+ pC+ g C C C G+ G FUN_001096-T2 254 CSS-PCISGV-C----AAKDICVCDRGFEGL 278 885.***998.*....6777*********96 PP == domain 3 score: 4.1 bits; conditional E-value: 0.026 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 C C G+C ++ tC C +Gy+G FUN_001096-T2 289 CGISGCGAYGKC----SSNDTCVCETGYFGH 315 66677999999*....6888*********95 PP == domain 4 score: 19.7 bits; conditional E-value: 3.4e-07 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 C+p pC ng +C+d++ ++ +C+C G+ G FUN_001096-T2 323 CNP-PCENG-RCIDNSTNSTKCFCEIGWEGQ 351 877.7*877.5******************96 PP >> PGF-CTERM PGF-CTERM motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 2.8 0.00029 0.92 5 22 .. 406 423 .. 406 424 .. 0.95 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00029 PGF-CTERM 5 GavlAlaGLLAaayLaRR 22 G++ A++G +++a++aR+ FUN_001096-T2 406 GVAAAIVGTATVAFIARK 423 899**************8 PP >> JAG1-like_EGF2 Protein jagged-1-like, atypical EGF2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 5.3 0.0063 20 3 23 .. 261 281 .. 253 282 .. 0.83 2 ? 9.6 1.9 0.00042 1.3 3 24 .. 298 319 .. 296 320 .. 0.94 3 ? 9.9 2.5 0.00032 1 3 23 .. 330 354 .. 328 355 .. 0.83 4 ? -4.0 0.3 7.3 2.3e+04 14 17 .. 428 431 .. 428 431 .. 0.91 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0063 JAG1-like_EGF2 3 GtCkepwqCtCdEGwgGlFCD 23 G C C Cd G+ Gl CD FUN_001096-T2 261 GVCAAKDICVCDRGFEGLNCD 281 55666689************9 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00042 JAG1-like_EGF2 3 GtCkepwqCtCdEGwgGlFCDq 24 G+C+ C C+ G+ G C q FUN_001096-T2 298 GKCSSNDTCVCETGYFGHLCNQ 319 99******************87 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00032 JAG1-like_EGF2 3 GtCkep....wqCtCdEGwgGlFCD 23 G+C C C+ Gw G FC FUN_001096-T2 330 GRCIDNstnsTKCFCEIGWEGQFCN 354 777766667789************5 PP == domain 4 score: -4.0 bits; conditional E-value: 7.3 JAG1-like_EGF2 14 dEGw 17 +EGw FUN_001096-T2 428 PEGW 431 7*** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (435 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 887 (0.034723); expected 510.9 (0.02) Passed bias filter: 412 (0.0161284); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4262.58 // Query: FUN_001097-T1 [L=113] Description: FUN_001097 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 12.3 0.2 0.6 10.9 0.0 1.7 2 DUF3040 Protein of unknown function (DUF3040) Domain annotation for each model (and alignments): >> DUF3040 Protein of unknown function (DUF3040) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.2 0.18 4.6e+03 71 79 .. 8 16 .. 2 21 .. 0.40 2 ? 10.9 0.0 2.4e-05 0.6 12 73 .. 36 93 .. 28 98 .. 0.60 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.18 DUF3040 71 gvvGfvvml 79 ++v f+v+l FUN_001097-T1 8 AAVIFLVLL 16 222233333 PP == domain 2 score: 10.9 bits; conditional E-value: 2.4e-05 DUF3040 12 eeiEraLaaeDPkfaarlrgtaaraarrrlrrlavlavllfvlGlvllvlG.valaqvvlgvv 73 +eiE++ ++e P+ ++ +a+++++r ++r ++++vl ++G+ + v+G ++ ++v+ vv FUN_001097-T1 36 DEIEEENRSEIPRHHRSD--EAHSRHKR-AERGRYRSVL--AVGVGCAVAGgWICLATVVYVV 93 677777777777776666..33333333.3333555554..4688887888776666566554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1216 (0.0476023); expected 510.9 (0.02) Passed bias filter: 726 (0.0284204); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1104.87 // Query: FUN_001098-T1 [L=376] Description: FUN_001098 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-73 245.8 2.1 7e-73 245.8 2.1 1.5 2 PSD13_N PSD13 N-terminal repeats 5.4e-13 49.4 0.1 1.4e-12 48.1 0.1 1.7 1 PCI PCI domain 4.5e-06 26.7 0.1 9e-06 25.7 0.1 1.6 1 Rpn9_C Rpn9 C-terminal helix Domain annotation for each model (and alignments): >> PSD13_N PSD13 N-terminal repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 245.8 2.1 8.2e-77 7e-73 2 224 .] 22 237 .. 21 237 .. 0.96 2 ? -2.6 0.0 0.76 6.4e+03 67 90 .. 267 290 .. 260 340 .. 0.45 Alignments for each domain: == domain 1 score: 245.8 bits; conditional E-value: 8.2e-77 PSD13_N 2 faeledlyerKLWhqLtlkLeeffkepks..eelrlelYenfiskfedkinqlklveillkvakqiedkeealefleklkeklvkekkqeakdeee 95 +a l +lye+KLWhqLtlkL++f+k++ + +e ++e+Yenf+++fe++in l+l+ei+l v+k+++d++ a+efle+ kek+++e e FUN_001098-T1 22 WAVLGELYEKKLWHQLTLKLAQFVKDDYFvqNEGLVEMYENFLADFEHRINMLSLMEIVLYVVKEMKDPDVAVEFLEREKEKIKNE--------VE 109 78899********************888888999************************************************6655........35 PP PSD13_N 96 avvllkleiarlklelgdlekakklleelekildsldsvetkvhaafYrvsaeyykakadyaeyYknaLlyLacvdledlseeekqelaydlsiAA 191 a vl+ ++i+++kl++g++e++k+++e++++il++ +++++vh++fY+++++y+k+++ y++yY++aL++L+cv+l+++ ++ek+++a +ls+AA FUN_001098-T1 110 AQVLCMTAIGNIKLQQGKMEDTKSIVEQARAILET-IDGVSSVHGRFYELCSNYHKITGSYNDYYRDALRFLGCVKLNTMAADEKVDRALHLSLAA 204 799********************************.89999******************************************************* PP PSD13_N 192 LlGdkiYnFGeLlahpiLkslketekewlvdLL 224 LlG +iYnFGeLlahpiL+slk+t++ wl++LL FUN_001098-T1 205 LLGSDIYNFGELLAHPILESLKGTQHGWLIELL 237 *******************************98 PP == domain 2 score: -2.6 bits; conditional E-value: 0.76 PSD13_N 67 dkeealefleklkeklvkekkqea 90 + ++++++l ++ ++++ +++++ FUN_001098-T1 267 NLQQKISLLCLMELTFKRPSNDRN 290 444444444444444444433333 PP >> PCI PCI domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.1 0.1 1.7e-16 1.4e-12 4 84 .] 251 335 .. 245 335 .. 0.94 Alignments for each domain: == domain 1 score: 48.1 bits; conditional E-value: 1.7e-16 PCI 4 ykeellqddglaelledLrrkirernlrqlsk....pyssislsdlakllglsvdevEkilaklIrdgrikakIDqvngivvvsk 84 +k+++ q+ +l+ +++L++ki +++l++l++ + +++s++ +ak+ +l+ +evE +++k+ + g++k++ID+v+++v++++ FUN_001098-T1 251 LKRHWQQQGDLNRNYKNLQQKISLLCLMELTFkrpsNDRNLSFEVIAKEAQLPLEEVELLVMKALSLGLVKGSIDEVEQMVHMTW 335 5777889999999**********************999********************************************986 PP >> Rpn9_C Rpn9 C-terminal helix # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.1 1.1e-09 9e-06 1 24 [. 339 362 .. 339 371 .. 0.90 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 1.1e-09 Rpn9_C 1 RildkdQIekMkqRLveWdenVnk 24 R+ld +QI+ M++RL +W + V++ FUN_001098-T1 339 RVLDLNQIAHMRDRLSDWCDKVKT 362 9*****************999985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (376 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1104 (0.0432179); expected 510.9 (0.02) Passed bias filter: 691 (0.0270503); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3628.62 // Query: FUN_001098-T2 [L=284] Description: FUN_001098 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-73 247.4 2.1 3e-73 247.0 2.1 1.1 1 PSD13_N PSD13 N-terminal repeats Domain annotation for each model (and alignments): >> PSD13_N PSD13 N-terminal repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 247.0 2.1 1.2e-77 3e-73 2 224 .] 22 237 .. 21 237 .. 0.96 Alignments for each domain: == domain 1 score: 247.0 bits; conditional E-value: 1.2e-77 PSD13_N 2 faeledlyerKLWhqLtlkLeeffkepks..eelrlelYenfiskfedkinqlklveillkvakqiedkeealefleklkeklvkekkqeakdeee 95 +a l +lye+KLWhqLtlkL++f+k++ + +e ++e+Yenf+++fe++in l+l+ei+l v+k+++d++ a+efle+ kek+++e e FUN_001098-T2 22 WAVLGELYEKKLWHQLTLKLAQFVKDDYFvqNEGLVEMYENFLADFEHRINMLSLMEIVLYVVKEMKDPDVAVEFLEREKEKIKNE--------VE 109 78899********************888888999************************************************6655........35 PP PSD13_N 96 avvllkleiarlklelgdlekakklleelekildsldsvetkvhaafYrvsaeyykakadyaeyYknaLlyLacvdledlseeekqelaydlsiAA 191 a vl+ ++i+++kl++g++e++k+++e++++il++ +++++vh++fY+++++y+k+++ y++yY++aL++L+cv+l+++ ++ek+++a +ls+AA FUN_001098-T2 110 AQVLCMTAIGNIKLQQGKMEDTKSIVEQARAILET-IDGVSSVHGRFYELCSNYHKITGSYNDYYRDALRFLGCVKLNTMAADEKVDRALHLSLAA 204 799********************************.89999******************************************************* PP PSD13_N 192 LlGdkiYnFGeLlahpiLkslketekewlvdLL 224 LlG +iYnFGeLlahpiL+slk+t++ wl++LL FUN_001098-T2 205 LLGSDIYNFGELLAHPILESLKGTQHGWLIELL 237 *******************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (284 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1079 (0.0422392); expected 510.9 (0.02) Passed bias filter: 678 (0.0265414); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 2742.03 // Query: FUN_001099-T1 [L=367] Description: FUN_001099 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.087 13.4 0.0 0.18 12.4 0.0 1.4 1 OSR1_C Oxidative-stress-responsive kinase 1 C-terminal do 0.21 11.6 0.4 0.32 11.0 0.4 1.2 1 PspA_IM30 PspA/IM30 family Domain annotation for each model (and alignments): >> OSR1_C Oxidative-stress-responsive kinase 1 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.4e-05 0.18 26 51 .. 210 236 .. 209 239 .. 0.87 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.4e-05 OSR1_C 26 FelekDt.aeevAqElvkaglvdeeDv 51 F+ e+D+ ++ +qE+v++gl+ ++D+ FUN_001099-T1 210 FTQETDSgSDQLSQEMVNTGLILKCDL 236 7888887469***************97 PP >> PspA_IM30 PspA/IM30 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.4 2.5e-05 0.32 98 143 .. 96 141 .. 90 157 .. 0.90 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 2.5e-05 PspA_IM30 98 kqaealetqlaeqrsaveqlrkqlealetkieelkakkellkarek 143 + a++ t+ + ++e lr+++++ +++ + +k+k++++ +++ FUN_001099-T1 96 QVAKGNTTSFTSKDVTIEGLREAISQFKRQSQSVKQKIQVVNIQSL 141 5688999999*******************************99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (367 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 954 (0.0373459); expected 510.9 (0.02) Passed bias filter: 724 (0.0283421); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3598.03 // Query: FUN_001100-T1 [L=154] Description: FUN_001100 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (154 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 834 (0.0326483); expected 510.9 (0.02) Passed bias filter: 436 (0.0170679); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.22u 0.42s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1569.73 // Query: FUN_001101-T1 [L=383] Description: FUN_001101 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-78 263.8 6.8 2.1e-78 263.4 6.8 1.1 1 ApeC C-terminal domain of apextrin ------ inclusion threshold ------ 0.059 13.5 0.1 0.087 12.9 0.1 1.2 1 Rib_5-P_isom_A Ribose 5-phosphate isomerase A (phosphoribois Domain annotation for each model (and alignments): >> ApeC C-terminal domain of apextrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 263.4 6.8 1.7e-82 2.1e-78 1 208 [] 151 353 .. 151 353 .. 0.99 Alignments for each domain: == domain 1 score: 263.4 bits; conditional E-value: 1.7e-82 ApeC 1 WPaGsYGlPkpvsgCpesegveWktGvrfqdtedddekskksaslhlagsvskegvkqefCikkdtkgeeerpeWpeGkYCiykkgdeCPagleeG 96 WP+G+YGlPkp++gCp+ + W++G+r++d e+ ++++ ks++ hl+g+v+ +g++qefCi+ +t++e+ +Wp+GkYCiykkg +CP gl+eG FUN_001101-T1 151 WPSGNYGLPKPRTGCPDRS---WREGFRYHDSENAENTNWKSNKSHLSGNVTLHGIRQEFCIHLNTRNEQI--PWPRGKYCIYKKGGTCPFGLHEG 241 ****************987...********************************************99887..*********************** PP ApeC 97 yirwdDensevdnenkesGtlPeGvYdentliefCCstkGskdtaikLPldspfyLlayesasCqkvkgakvteeflkfddedeenkdaeggahPy 192 ++rwdDens++d +n+ G++P+G+Y+ent i+fCCs +G++++ai LP +spfyL+a++s++Cq+v++ kvt e+l+fdded+ n+++++ P+ FUN_001101-T1 242 WVRWDDENSKIDYPNSLGGEVPDGSYGENTIIYFCCSISGKNSDAILLPHKSPFYLIAFGSSECQQVQNHKVTLEYLQFDDEDQGNSNSHSRLAPF 337 ************************************************************************************************ PP ApeC 193 lvtkkkkdltlyyCyY 208 +++++++++++yyCyY FUN_001101-T1 338 GTAQDPYNTRIYYCYY 353 ***************9 PP >> Rib_5-P_isom_A Ribose 5-phosphate isomerase A (phosphoriboisomerase A) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.1 6.8e-06 0.087 107 159 .. 74 122 .. 36 129 .. 0.79 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 6.8e-06 Rib_5-P_isom_A 107 kpklReakgkdgpvvTdngnlilDvkfeeiiedpeelekelkkipGVvetGlF 159 +lRe ++++ v T + n+i+D+++ + + ++++ +++++ Vv++G + FUN_001101-T1 74 VIQLRE--QDANNVSTIQRNIIVDMQL-SFY-NRSRVNGSIENLFSVVQSGAL 122 348998..6679***************.344.99***************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (383 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 756 (0.0295948); expected 510.9 (0.02) Passed bias filter: 577 (0.0225876); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3694.67 // Query: FUN_001102-T1 [L=1617] Description: FUN_001102 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-88 297.7 4.1 6.9e-47 161.0 0.0 2.2 2 WD40_RLD RCC1-like domain 7.5e-83 273.4 18.6 1.7e-15 57.8 0.3 8.9 9 RCC1 Regulator of chromosome condensati 9.2e-39 130.8 41.3 2.5e-08 34.0 2.7 7.8 7 RCC1_2 Regulator of chromosome condensati 6e-17 62.3 5.4 2.1e-06 27.6 0.2 5.0 5 Alsin_RLD Alsin RCC1-like domain 0.00023 20.7 0.5 0.00091 18.8 0.1 2.1 2 Pep3_Vps18 Pep3/Vps18/deep orange beta-propel 0.00043 20.3 1.0 0.0013 18.8 0.1 2.2 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 0.0068 17.2 0.2 0.16 12.8 0.1 2.9 2 RHG29_45_N Rho GTPase-activating protein 29/4 ------ inclusion threshold ------ 0.014 15.3 0.1 0.19 11.5 0.0 2.3 2 Beta-prop_EML_2 Echinoderm microtubule-associated 0.068 14.3 0.2 1.4 10.1 0.0 3.3 2 WD40 WD domain, G-beta repeat Domain annotation for each model (and alignments): >> WD40_RLD RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 137.7 2.4 2.9e-43 8.3e-40 196 346 .. 811 965 .. 789 971 .. 0.84 2 ! 161.0 0.0 2.4e-50 6.9e-47 82 299 .. 966 1203 .. 960 1214 .. 0.81 Alignments for each domain: == domain 1 score: 137.7 bits; conditional E-value: 2.9e-43 WD40_RLD 196 kvvdiaaGsyhsfaltedgkvyawGlNnygqlGlgstenrv...sPtkv...eeslkgvkqiagGehhslaltedgevyawGrndygqlGlgeeee 285 + v+ ++G+ h+++++++g+vy+wG+ + g+lG+g+ ++ +P +v +++ +v ++a+G +h+lal+ dg vy+wG+++ygqlG+g++++ FUN_001102-T1 811 RPVRLSCGQLHTAVVSSSGDVYTWGKSQRGRLGHGDLIEEEgksFPFRVeilHMHKINVLSVACGMEHTLALCWDG-VYSWGSSQYGQLGQGDTQQ 905 456789****************************55444444457888753444444488999*************.***************9999 PP WD40_RLD 286 esePtkvpglegvkvvqiaaGsehslavtedgkvyswGfgesgqlGlgdeeedvvePtlve 346 +++P+ v++l+++k++ +a+G +hsla++ d +v+swG+g +gqlG g+ edv+ Pt++ FUN_001102-T1 906 QTRPVYVTELSDKKCIAVACGHYHSLALSVDHRVWSWGWGVHGQLGVGSI-EDVLLPTHIA 965 9***********************************************76.68999*9987 PP == domain 2 score: 161.0 bits; conditional E-value: 2.4e-50 WD40_RLD 82 geveeleg.kvvqvaaGdshslaltedGevyawGrnseGqlGlgeekkqktPvkvveklekekvkkiaaGanhslaltedgevytwGsg.eqgq 173 g l++ +++q+aaG shs++l+ +G+v+++G + +GqlGlg++ kq +P++v e+l+ke+v i++G+ +la+te ++++ wG++ ++ + FUN_001102-T1 966 G----LDEfEITQLAAGYSHSAVLSAKGQVFTFGGGLYGQLGLGTNCKQVVPQLV-ESLAKERVYLICCGSFETLAVTEGQKIFNWGRSpHFFR 1054 3....66657******************************************887.99*******************************89899 PP WD40_RLD 174 Lg....kkser.........rresklealvpkkv.....gkvvdiaaGsyhsfaltedgkvyawGlNnygqlGlgstenrv.sPtkv.eeslkg 247 + r +s +++l p k+ +++ d+++G+ h ++l e+g++y+wG N+ygqlGlg++ ++ +P+ + + + k+ FUN_001102-T1 1055 FYmrqeH---RakrstqanvPMSSLSHRLLPVKIdclfsSRINDVCCGNCHYLVLLESGQLYSWGFNDYGQLGLGNKMDSPmTPRLIhKLANKH 1145 9855441...1222322222333355556666658899777*********************************98888888**9996666666 PP WD40_RLD 248 vkqiagGehhslaltedgevyawGrndygqlGlg......eeeeesePtkvpglegvk 299 +++i+ G + s+a+++ g vy+wGr+d+gqlGl+ +++e s P ++++l+ + FUN_001102-T1 1146 ITSISVGAECSAAMDAAGLVYVWGRADSGQLGLEfssigaNRKEVSLPCQITSLPPLN 1203 ********************************99766655444455588888777655 PP >> RCC1 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 8.5 2.4e+04 36 43 .. 53 60 .. 48 62 .. 0.74 2 ? 1.2 0.0 0.27 7.8e+02 32 50 .] 809 825 .. 800 825 .. 0.79 3 ! 45.7 0.0 3.7e-15 1e-11 1 50 [] 828 882 .. 828 882 .. 0.92 4 ! 57.8 0.3 5.9e-19 1.7e-15 3 50 .] 886 933 .. 885 933 .. 0.97 5 ! 50.9 0.1 8.5e-17 2.4e-13 1 50 [] 936 985 .. 936 985 .. 0.97 6 ! 44.6 0.4 7.8e-15 2.2e-11 1 50 [] 988 1037 .. 988 1037 .. 0.96 7 ? 5.7 0.1 0.011 31 21 50 .] 1077 1106 .. 1068 1106 .. 0.86 8 ! 49.7 0.0 2.1e-16 5.8e-13 1 49 [. 1109 1158 .. 1109 1159 .. 0.95 9 ! 22.8 0.0 5.1e-08 0.00014 2 33 .. 1163 1200 .. 1162 1206 .. 0.87 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 8.5 RCC1 36 kvvqvacG 43 ++qvac FUN_001102-T1 53 SIQQVACH 60 799****6 PP == domain 2 score: 1.2 bits; conditional E-value: 0.27 RCC1 32 lsgnkvvqvacGadhtval 50 l + v +cG+ ht+++ FUN_001102-T1 809 LC--RPVRLSCGQLHTAVV 825 43..78999*******986 PP == domain 3 score: 45.7 bits; conditional E-value: 3.7e-15 RCC1 1 dGrvytWGrneyGqLGlgte...esklvPqkveslsgn..kvvqvacGadhtval 50 +G+vytWG+ ++G+LG+g+ e k+ P +ve l + +v +vacG +ht+al FUN_001102-T1 828 SGDVYTWGKSQRGRLGHGDLieeEGKSFPFRVEILHMHkiNVLSVACGMEHTLAL 882 59******************76555599*******9999**************97 PP == domain 4 score: 57.8 bits; conditional E-value: 5.9e-19 RCC1 3 rvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 vy+WG+ +yGqLG+g+++++ P+ v+ ls++k + vacG++h++al FUN_001102-T1 886 GVYSWGSSQYGQLGQGDTQQQTRPVYVTELSDKKCIAVACGHYHSLAL 933 59********************************************97 PP == domain 5 score: 50.9 bits; conditional E-value: 8.5e-17 RCC1 1 dGrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 d rv++WG++ +GqLG g+ e++l+P+ + +l++ +++q a+G++h+++l FUN_001102-T1 936 DHRVWSWGWGVHGQLGVGSIEDVLLPTHIAGLDEFEITQLAAGYSHSAVL 985 789********************************************987 PP == domain 6 score: 44.6 bits; conditional E-value: 7.8e-15 RCC1 1 dGrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 +G+v+t+G + yGqLGlgt++++ vPq+vesl + +v ++cG+ t+a+ FUN_001102-T1 988 KGQVFTFGGGLYGQLGLGTNCKQVVPQLVESLAKERVYLICCGSFETLAV 1037 6********************************99*********999986 PP == domain 7 score: 5.7 bits; conditional E-value: 0.011 RCC1 21 esklvPqkveslsgnkvvqvacGadhtval 50 +++l+P+k+ l + ++ +v+cG+ h ++l FUN_001102-T1 1077 SHRLLPVKIDCLFSSRINDVCCGNCHYLVL 1106 56789****999999*********997765 PP == domain 8 score: 49.7 bits; conditional E-value: 2.1e-16 RCC1 1 dGrvytWGrneyGqLGlgte.esklvPqkveslsgnkvvqvacGadhtva 49 +G++y+WG+n+yGqLGlg++ +s +P+++ l +++++++++Ga+ ++a FUN_001102-T1 1109 SGQLYSWGFNDYGQLGLGNKmDSPMTPRLIHKLANKHITSISVGAECSAA 1158 69******************888899**********************98 PP == domain 9 score: 22.8 bits; conditional E-value: 5.1e-08 RCC1 2 GrvytWGrneyGqLGl.....gte.esklvPqkvesls 33 G vy WGr + GqLGl g + +++++P++++sl+ FUN_001102-T1 1163 GLVYVWGRADSGQLGLefssiGANrKEVSLPCQITSLP 1200 99**************9988844448889*****9986 PP >> RCC1_2 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.2 1.3e-08 3.8e-05 4 29 .. 815 840 .. 813 841 .. 0.93 2 ! 21.6 1.4 6.9e-08 0.0002 2 30 .] 870 897 .. 869 897 .. 0.96 3 ! 29.1 4.3 2.9e-10 8.3e-07 2 30 .] 921 949 .. 920 949 .. 0.97 4 ! 26.7 0.3 1.7e-09 4.8e-06 1 30 [] 972 1001 .. 972 1001 .. 0.98 5 ? 3.8 0.0 0.027 77 4 26 .. 1027 1049 .. 1024 1051 .. 0.90 6 ! 34.0 2.7 8.8e-12 2.5e-08 2 30 .] 1094 1122 .. 1093 1122 .. 0.96 7 ! 13.4 0.1 2.6e-05 0.075 1 30 [] 1146 1175 .. 1146 1175 .. 0.98 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 1.3e-08 RCC1_2 4 vaaGdnHslaLtsdGrvycwGdNsyG 29 +++G H+ +++s+G+vy+wG +++G FUN_001102-T1 815 LSCGQLHTAVVSSSGDVYTWGKSQRG 840 79********************9998 PP == domain 2 score: 21.6 bits; conditional E-value: 6.9e-08 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 sva+G H+laL dG vy+wG+++yGQ FUN_001102-T1 870 LSVACGMEHTLALCWDG-VYSWGSSQYGQ 897 59***************.**********9 PP == domain 3 score: 29.1 bits; conditional E-value: 2.9e-10 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++va+G +HslaL+ d rv++wG++ +GQ FUN_001102-T1 921 IAVACGHYHSLALSVDHRVWSWGWGVHGQ 949 68**************************9 PP == domain 4 score: 26.7 bits; conditional E-value: 1.7e-09 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++++aaG++Hs +L++ G+v+++G + yGQ FUN_001102-T1 972 ITQLAAGYSHSAVLSAKGQVFTFGGGLYGQ 1001 89***************************9 PP == domain 5 score: 3.8 bits; conditional E-value: 0.027 RCC1_2 4 vaaGdnHslaLtsdGrvycwGdN 26 +++G++ +la+t+ +++ wG++ FUN_001102-T1 1027 ICCGSFETLAVTEGQKIFNWGRS 1049 89****************99985 PP == domain 6 score: 34.0 bits; conditional E-value: 8.8e-12 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 +v++G+ H+l+L+++G++y+wG N+yGQ FUN_001102-T1 1094 NDVCCGNCHYLVLLESGQLYSWGFNDYGQ 1122 68**************************9 PP == domain 7 score: 13.4 bits; conditional E-value: 2.6e-05 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++s+++G+ s a ++ G vy+wG+ ++GQ FUN_001102-T1 1146 ITSISVGAECSAAMDAAGLVYVWGRADSGQ 1175 89***************************9 PP >> Alsin_RLD Alsin RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.1 8.5e-07 0.0024 252 317 .. 830 899 .. 818 899 .. 0.83 2 ! 27.6 0.2 7.5e-10 2.1e-06 252 329 .. 886 965 .. 881 991 .. 0.81 3 ! 5.5 0.0 0.0038 11 250 309 .. 988 1047 .. 968 1054 .. 0.84 4 ! 10.3 0.0 0.00013 0.37 288 326 .. 1095 1133 .. 1082 1138 .. 0.87 5 ! 18.3 0.0 5e-07 0.0014 250 324 .. 1109 1182 .. 1102 1204 .. 0.84 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 8.5e-07 Alsin_RLD 252 qlftlGasnkGllGtGdhikrasv...arle..kldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlg 317 ++t G s +G lG Gd i + r+e ++++ v s+a+G eht++ dG +y wG + qlg FUN_001102-T1 830 DVYTWGKSQRGRLGHGDLIEEEGKsfpFRVEilHMHKINVLSVACGMEHTLALCWDG-VYSWGSSQYGQLG 899 689****************9764312256762255789*******************.7****99999986 PP == domain 2 score: 27.6 bits; conditional E-value: 7.5e-10 Alsin_RLD 252 qlftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlgn..ieelsspleis 329 +++ G+s G lG Gd ++ + + + l + ++a+G+ h+++ ++d r++ wG + qlg ie++ p+ i+ FUN_001102-T1 886 GVYSWGSSQYGQLGQGDTQQQTRPVYVTELSDKKCIAVACGHYHSLALSVDHRVWSWGWGVHGQLGVgsIEDVLLPTHIA 965 689*************************************************************9855588888888775 PP == domain 3 score: 5.5 bits; conditional E-value: 0.0038 Alsin_RLD 250 ntqlftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwG 309 + q+ft+G G lG G k+ + +e l + v i +G t++ t +++ wG FUN_001102-T1 988 KGQVFTFGGGLYGQLGLGTNCKQVVPQLVESLAKERVYLICCGSFETLAVTEGQKIFNWG 1047 569999999999999999999999999999999999999999999999999999999999 PP == domain 4 score: 10.3 bits; conditional E-value: 0.00013 Alsin_RLD 288 siaaGkehtvvrtldGrlyhwGlndkeqlgnieelsspl 326 + +G+ h +v G+ly wG+nd qlg +++ sp+ FUN_001102-T1 1095 DVCCGNCHYLVLLESGQLYSWGFNDYGQLGLGNKMDSPM 1133 577899999999999***************999999998 PP == domain 5 score: 18.3 bits; conditional E-value: 5e-07 Alsin_RLD 250 ntqlftlGasnkGllGtGdhikrasvarl.ekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlgnieelss 324 ql++ G ++ G lG G+++ rl +kl + + si++G e + + G +y wG d qlg e+ss FUN_001102-T1 1109 SGQLYSWGFNDYGQLGLGNKMDSPMTPRLiHKLANKHITSISVGAECSAAMDAAGLVYVWGRADSGQLG--LEFSS 1182 46*******************9999888549**************************************..66665 PP >> Pep3_Vps18 Pep3/Vps18/deep orange beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.1 3.2e-07 0.00091 16 233 .. 57 305 .. 44 320 .. 0.70 2 ? -2.3 0.0 0.85 2.4e+03 182 258 .. 556 639 .. 514 650 .. 0.68 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 3.2e-07 Pep3_Vps18 16 litslqVsnnvlvlalsngrllridLdnpedvdeielpkksseegkirkiFLdptgshllistnlgenyy..................lhtqskkp 93 ++ + n +vl ++ng ll+ +n ++ +++ ++ ++ir i Ldp+gs l+ ++ + +y+ ++ ++ FUN_001102-T1 57 VACHEDAKYNLIVLLCNNGSLLLKAEENGKSPVIKQVSWFQNPAKSIRAITLDPSGSWLMCACMDASLYIvpvagmvmvkpqvscsywATEDL-SL 151 556777788*******************99999888888888888********************999999****999988876654322222.23 PP Pep3_Vps18 94 kklsklkgvdIesVaWnkseatastreiLiGtadGkiyetelepseffkkeekyvkqvyklpekepitGlqfekvpesrrylvlvat...psrlyq 186 +k +g+ + V W+ + + + +iGt+ G+i ++l +v++++ ke+it l++ + ++++++++l++t ++ +q FUN_001102-T1 152 ILETKNRGLPSSVVWWH-TVDDLDIG--IIGTELGEILFVDLRL----------KVTVASVEAKESITSLKLMQDKQHETTALLINTvsgDTVQMQ 234 33334466655555554.33334444..**************64..........346788887788999987777644444444444232233445 PP Pep3_Vps18 187 fvgkvsskgseeeksl........................fsklFssykeeapkfqelpgelayselavsp 233 ++ k ++k+s+++ ++ ++++Fs + + + k++ +p +++ ++ ++s+ FUN_001102-T1 235 LEYKSMHKTSSDQIRScsfsvttsmavamgyealskrtipMESVFSGMGDLQDKIRPMPVTSSSGSTQFSV 305 55544444443333224545566666676766666666666999999999999999998877777777776 PP == domain 2 score: -2.3 bits; conditional E-value: 0.85 Pep3_Vps18 182 srlyqfvgkvsskgseeek.slfsklFssykeeapkfqel...pgelayselavsp.seekk...lpksfAwltssGiyhgklnf 258 +l+ f+++v +++s+ k s +s+ Fs+ +++ ++ e+ + +la l+ ++ k+ +++++ +l ++G +h +l+ FUN_001102-T1 556 LTLMCFIQQVLNSSSDAIKySELSDAFSQFLNDNFDYDEVtalE-QLAAYGLKGFMfDLAKArglMERALEILAQKGQFHLSLEL 639 57999999988887774333668888888887777777773322.2333333333322222257788888888888888888876 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.1 4.4e-07 0.0013 128 231 .. 137 244 .. 47 264 .. 0.80 2 ? -2.2 0.1 1.1 3.1e+03 15 83 .. 503 571 .. 495 604 .. 0.70 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 4.4e-07 Beta-prop_WDR36-Utp21_1st 128 kqGslqlwNirtgkliytfk..sfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDg...ep 206 q s w + +li ++k ++ s++ + ld+ ig++ Gei++++++ t+ +++++ +++ts+ +D+ + FUN_001102-T1 137 PQVSCSYWATEDLSLILETKnrGLPSSVVWWHTVDDLDIGIIGTELGEILFVDLRLKVTVASVEAK-ESITSLKLMQDKqheTT 219 55566677788888888886335569999999999*****************************99.9**********844357 PP Beta-prop_WDR36-Utp21_1st 207 vlatgsssGdialwdLekrrlvhvl 231 l++ + sGd + Le ++++++ FUN_001102-T1 220 ALLINTVSGDTVQMQLEYKSMHKTS 244 999*********9999999877665 PP == domain 2 score: -2.2 bits; conditional E-value: 1.1 Beta-prop_WDR36-Utp21_1st 15 sklrllfvse.qlpekItalaadkdlvfaavgnkivvfkrgkevaellkeheekikkllvfgdhlvavde 83 + l+l +s+ +++++++++a ++ v +g+ v+++ v++ ++++ ++++ ++ ++++l + ++ FUN_001102-T1 503 RALELYHLSKcPFEKQVSQFAKHE-RVADILGHLRQVLNKHGDVHTAERKQLSNLTLMCFIQQVLNSSSD 571 458899999989999999887665.555666666667777777888888888888888888888877665 PP >> RHG29_45_N Rho GTPase-activating protein 29/45 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.1 5.5e-05 0.16 31 66 .. 519 554 .. 500 587 .. 0.73 2 ? 0.3 0.0 0.41 1.2e+03 28 74 .. 1466 1514 .. 1449 1530 .. 0.71 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 5.5e-05 RHG29_45_N 31 elrvvaherLgevLriLkavlekypaLnsteilsaa 66 + + her++++L L++vl+k+ +++ e + + FUN_001102-T1 519 VSQFAKHERVADILGHLRQVLNKHGDVHTAERKQLS 554 446678*********************998865544 PP == domain 2 score: 0.3 bits; conditional E-value: 0.41 RHG29_45_N 28 keeelrvvaherLgevLriLkavlekyp..aLnsteilsaagaliskvk 74 +++e++ + + +e+L +k+ l+++p aL +t + a+a +s+ + FUN_001102-T1 1466 QKREFHAAQSHMWQEILDNIKKDLDRHPciALSTTAAATVASAAVSQQR 1514 45678888888899*************9434556666666666666655 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 6.7e-05 0.19 43 111 .. 55 130 .. 39 141 .. 0.78 2 ? 0.8 0.1 0.13 3.6e+02 25 136 .. 144 257 .. 138 268 .. 0.62 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 6.7e-05 Beta-prop_EML_2 43 rsvafspdgk..llavGlkdGsvlvldaetl.....eevvevkdrkeaisdikfspdgklLavgshdnkiylYdvs 111 + va+++d k l+++ +++Gs+l+ +e++ ++v +++ ++i++i+ p+g++L +++ d ++y+ v+ FUN_001102-T1 55 QQVACHEDAKynLIVLLCNNGSLLLKAEENGkspviKQVSWFQNPAKSIRAITLDPSGSWLMCACMDASLYIVPVA 130 5566776665226888899****9998888621111455578999**************************97765 PP == domain 2 score: 0.8 bits; conditional E-value: 0.13 Beta-prop_EML_2 25 Wdlekkklvakvklekearsvafspdgkll...avGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskkyk 115 W +e+ +l+ ++k + +sv + + + l ++G++ G++l +d + l+++v+ + ke+i+ +k +d+++ + n++ +v+ +++ FUN_001102-T1 144 WATEDLSLILETKNRGLPSSVVWWHTVDDLdigIIGTELGEILFVDLR-LKVTVASVEAKESITSLKLMQDKQHETTALLINTVSGDTVQMQLE 236 556666666666555555555554433333112667788888888744.455555566788888888888887777777666666666666666 PP Beta-prop_EML_2 116 kvgklkghssfithlDwseds 136 ++ k +s+ i+++ +s FUN_001102-T1 237 YKSMHKTSSDQIRSCSFSVTT 257 666666677777777777554 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.00048 1.4 11 37 .. 100 126 .. 91 127 .. 0.85 2 ? -1.2 0.0 1.9 5.3e+03 11 25 .. 245 259 .. 237 264 .. 0.70 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00048 WD40 11 tsgVtslafspdgsllasgsdDgtvkl 37 +++++++ +p+gs+l ++++D ++++ FUN_001102-T1 100 AKSIRAITLDPSGSWLMCACMDASLYI 126 5679******************99986 PP == domain 2 score: -1.2 bits; conditional E-value: 1.9 WD40 11 tsgVtslafspdgsl 25 ++ ++s++fs + s+ FUN_001102-T1 245 SDQIRSCSFSVTTSM 259 344******988776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1617 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 980 (0.0383637); expected 510.9 (0.02) Passed bias filter: 788 (0.0308475); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.57u 0.42s 00:00:00.99 Elapsed: 00:00:00.44 # Mc/sec: 14791.89 // Query: FUN_001102-T2 [L=1276] Description: FUN_001102 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-89 298.7 4.1 4.8e-47 161.5 0.0 2.2 2 WD40_RLD RCC1-like domain 9.8e-84 276.3 18.6 1.3e-15 58.2 0.3 8.9 9 RCC1 Regulator of chromosome condensati 1.3e-39 133.4 41.3 1.9e-08 34.3 2.7 7.9 7 RCC1_2 Regulator of chromosome condensati 1.1e-16 61.5 7.9 2.7e-07 30.6 0.7 5.1 6 Alsin_RLD Alsin RCC1-like domain 0.00019 21.0 0.7 0.00063 19.3 0.1 2.0 3 Pep3_Vps18 Pep3/Vps18/deep orange beta-propel 0.0002 21.4 0.7 0.00091 19.2 0.1 2.4 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 0.0079 16.1 0.1 0.13 12.1 0.0 2.3 2 Beta-prop_EML_2 Echinoderm microtubule-associated ------ inclusion threshold ------ 0.033 15.0 0.1 0.12 13.2 0.1 1.9 1 RHG29_45_N Rho GTPase-activating protein 29/4 0.089 13.9 1.4 0.96 10.6 0.0 3.5 3 WD40 WD domain, G-beta repeat 1.7 8.6 3.5 26 4.8 0.2 2.4 2 Znf_XAF1_N XIAP-associated factor 1-like, N-t Domain annotation for each model (and alignments): >> WD40_RLD RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.1 2.4 2.4e-43 6.2e-40 196 346 .. 811 965 .. 790 971 .. 0.84 2 ! 161.5 0.0 1.9e-50 4.8e-47 82 299 .. 966 1203 .. 960 1214 .. 0.81 Alignments for each domain: == domain 1 score: 138.1 bits; conditional E-value: 2.4e-43 WD40_RLD 196 kvvdiaaGsyhsfaltedgkvyawGlNnygqlGlgstenrv...sPtkv...eeslkgvkqiagGehhslaltedgevyawGrndygqlGlgeeee 285 + v+ ++G+ h+++++++g+vy+wG+ + g+lG+g+ ++ +P +v +++ +v ++a+G +h+lal+ dg vy+wG+++ygqlG+g++++ FUN_001102-T2 811 RPVRLSCGQLHTAVVSSSGDVYTWGKSQRGRLGHGDLIEEEgksFPFRVeilHMHKINVLSVACGMEHTLALCWDG-VYSWGSSQYGQLGQGDTQQ 905 456789****************************55444444457888753444444488999*************.***************9999 PP WD40_RLD 286 esePtkvpglegvkvvqiaaGsehslavtedgkvyswGfgesgqlGlgdeeedvvePtlve 346 +++P+ v++l+++k++ +a+G +hsla++ d +v+swG+g +gqlG g+ edv+ Pt++ FUN_001102-T2 906 QTRPVYVTELSDKKCIAVACGHYHSLALSVDHRVWSWGWGVHGQLGVGSI-EDVLLPTHIA 965 9***********************************************76.68999*9987 PP == domain 2 score: 161.5 bits; conditional E-value: 1.9e-50 WD40_RLD 82 geveeleg.kvvqvaaGdshslaltedGevyawGrnseGqlGlgeekkqktPvkvveklekekvkkiaaGanhslaltedgevytwGsg.eqgq 173 g l++ +++q+aaG shs++l+ +G+v+++G + +GqlGlg++ kq +P++v e+l+ke+v i++G+ +la+te ++++ wG++ ++ + FUN_001102-T2 966 G----LDEfEITQLAAGYSHSAVLSAKGQVFTFGGGLYGQLGLGTNCKQVVPQLV-ESLAKERVYLICCGSFETLAVTEGQKIFNWGRSpHFFR 1054 3....66657******************************************887.99*******************************89899 PP WD40_RLD 174 Lg....kkser.........rresklealvpkkv.....gkvvdiaaGsyhsfaltedgkvyawGlNnygqlGlgstenrv.sPtkv.eeslkg 247 + r +s +++l p k+ +++ d+++G+ h ++l e+g++y+wG N+ygqlGlg++ ++ +P+ + + + k+ FUN_001102-T2 1055 FYmrqeH---RakrstqanvPMSSLSHRLLPVKIdclfsSRINDVCCGNCHYLVLLESGQLYSWGFNDYGQLGLGNKMDSPmTPRLIhKLANKH 1145 9855441...1222322222333355556666658899777*********************************98888888**9996666666 PP WD40_RLD 248 vkqiagGehhslaltedgevyawGrndygqlGlg......eeeeesePtkvpglegvk 299 +++i+ G + s+a+++ g vy+wGr+d+gqlGl+ +++e s P ++++l+ + FUN_001102-T2 1146 ITSISVGAECSAAMDAAGLVYVWGRADSGQLGLEfssigaNRKEVSLPCQITSLPPLN 1203 ********************************99766655444455588888777655 PP >> RCC1 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 7.3 1.9e+04 36 43 .. 53 60 .. 48 62 .. 0.74 2 ? 1.6 0.0 0.24 6e+02 32 50 .] 809 825 .. 800 825 .. 0.79 3 ! 46.0 0.0 3.1e-15 7.9e-12 1 50 [] 828 882 .. 828 882 .. 0.92 4 ! 58.2 0.3 5e-19 1.3e-15 3 50 .] 886 933 .. 885 933 .. 0.97 5 ! 51.3 0.1 7.2e-17 1.9e-13 1 50 [] 936 985 .. 936 985 .. 0.97 6 ! 45.0 0.4 6.6e-15 1.7e-11 1 50 [] 988 1037 .. 988 1037 .. 0.96 7 ! 6.1 0.1 0.0095 24 21 50 .] 1077 1106 .. 1068 1106 .. 0.86 8 ! 50.1 0.0 1.7e-16 4.4e-13 1 49 [. 1109 1158 .. 1109 1159 .. 0.95 9 ! 23.2 0.0 4.3e-08 0.00011 2 33 .. 1163 1200 .. 1162 1206 .. 0.87 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 7.3 RCC1 36 kvvqvacG 43 ++qvac FUN_001102-T2 53 SIQQVACH 60 799****6 PP == domain 2 score: 1.6 bits; conditional E-value: 0.24 RCC1 32 lsgnkvvqvacGadhtval 50 l + v +cG+ ht+++ FUN_001102-T2 809 LC--RPVRLSCGQLHTAVV 825 43..78999*******986 PP == domain 3 score: 46.0 bits; conditional E-value: 3.1e-15 RCC1 1 dGrvytWGrneyGqLGlgte...esklvPqkveslsgn..kvvqvacGadhtval 50 +G+vytWG+ ++G+LG+g+ e k+ P +ve l + +v +vacG +ht+al FUN_001102-T2 828 SGDVYTWGKSQRGRLGHGDLieeEGKSFPFRVEILHMHkiNVLSVACGMEHTLAL 882 59******************76555599*******9999**************97 PP == domain 4 score: 58.2 bits; conditional E-value: 5e-19 RCC1 3 rvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 vy+WG+ +yGqLG+g+++++ P+ v+ ls++k + vacG++h++al FUN_001102-T2 886 GVYSWGSSQYGQLGQGDTQQQTRPVYVTELSDKKCIAVACGHYHSLAL 933 59********************************************97 PP == domain 5 score: 51.3 bits; conditional E-value: 7.2e-17 RCC1 1 dGrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 d rv++WG++ +GqLG g+ e++l+P+ + +l++ +++q a+G++h+++l FUN_001102-T2 936 DHRVWSWGWGVHGQLGVGSIEDVLLPTHIAGLDEFEITQLAAGYSHSAVL 985 789********************************************987 PP == domain 6 score: 45.0 bits; conditional E-value: 6.6e-15 RCC1 1 dGrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 +G+v+t+G + yGqLGlgt++++ vPq+vesl + +v ++cG+ t+a+ FUN_001102-T2 988 KGQVFTFGGGLYGQLGLGTNCKQVVPQLVESLAKERVYLICCGSFETLAV 1037 6********************************99*********999986 PP == domain 7 score: 6.1 bits; conditional E-value: 0.0095 RCC1 21 esklvPqkveslsgnkvvqvacGadhtval 50 +++l+P+k+ l + ++ +v+cG+ h ++l FUN_001102-T2 1077 SHRLLPVKIDCLFSSRINDVCCGNCHYLVL 1106 56789****999999*********997765 PP == domain 8 score: 50.1 bits; conditional E-value: 1.7e-16 RCC1 1 dGrvytWGrneyGqLGlgte.esklvPqkveslsgnkvvqvacGadhtva 49 +G++y+WG+n+yGqLGlg++ +s +P+++ l +++++++++Ga+ ++a FUN_001102-T2 1109 SGQLYSWGFNDYGQLGLGNKmDSPMTPRLIHKLANKHITSISVGAECSAA 1158 69******************888899**********************98 PP == domain 9 score: 23.2 bits; conditional E-value: 4.3e-08 RCC1 2 GrvytWGrneyGqLGl.....gte.esklvPqkvesls 33 G vy WGr + GqLGl g + +++++P++++sl+ FUN_001102-T2 1163 GLVYVWGRADSGQLGLefssiGANrKEVSLPCQITSLP 1200 99**************9988844448889*****9986 PP >> RCC1_2 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.2 1.1e-08 2.9e-05 4 29 .. 815 840 .. 813 841 .. 0.93 2 ! 21.9 1.4 5.9e-08 0.00015 2 30 .] 870 897 .. 869 897 .. 0.96 3 ! 29.5 4.3 2.5e-10 6.3e-07 2 30 .] 921 949 .. 920 949 .. 0.97 4 ! 27.1 0.3 1.5e-09 3.7e-06 1 30 [] 972 1001 .. 972 1001 .. 0.98 5 ? 4.1 0.0 0.023 60 4 26 .. 1027 1049 .. 1024 1051 .. 0.90 6 ! 34.3 2.7 7.5e-12 1.9e-08 2 30 .] 1094 1122 .. 1093 1122 .. 0.96 7 ! 13.7 0.1 2.3e-05 0.058 1 30 [] 1146 1175 .. 1146 1175 .. 0.98 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 1.1e-08 RCC1_2 4 vaaGdnHslaLtsdGrvycwGdNsyG 29 +++G H+ +++s+G+vy+wG +++G FUN_001102-T2 815 LSCGQLHTAVVSSSGDVYTWGKSQRG 840 79********************9998 PP == domain 2 score: 21.9 bits; conditional E-value: 5.9e-08 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 sva+G H+laL dG vy+wG+++yGQ FUN_001102-T2 870 LSVACGMEHTLALCWDG-VYSWGSSQYGQ 897 59***************.**********9 PP == domain 3 score: 29.5 bits; conditional E-value: 2.5e-10 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++va+G +HslaL+ d rv++wG++ +GQ FUN_001102-T2 921 IAVACGHYHSLALSVDHRVWSWGWGVHGQ 949 68**************************9 PP == domain 4 score: 27.1 bits; conditional E-value: 1.5e-09 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++++aaG++Hs +L++ G+v+++G + yGQ FUN_001102-T2 972 ITQLAAGYSHSAVLSAKGQVFTFGGGLYGQ 1001 89***************************9 PP == domain 5 score: 4.1 bits; conditional E-value: 0.023 RCC1_2 4 vaaGdnHslaLtsdGrvycwGdN 26 +++G++ +la+t+ +++ wG++ FUN_001102-T2 1027 ICCGSFETLAVTEGQKIFNWGRS 1049 89****************99985 PP == domain 6 score: 34.3 bits; conditional E-value: 7.5e-12 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 +v++G+ H+l+L+++G++y+wG N+yGQ FUN_001102-T2 1094 NDVCCGNCHYLVLLESGQLYSWGFNDYGQ 1122 68**************************9 PP == domain 7 score: 13.7 bits; conditional E-value: 2.3e-05 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++s+++G+ s a ++ G vy+wG+ ++GQ FUN_001102-T2 1146 ITSISVGAECSAAMDAAGLVYVWGRADSGQ 1175 89***************************9 PP >> Alsin_RLD Alsin RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 3.1 7.9e+03 207 264 .. 230 283 .. 214 294 .. 0.58 2 ! 17.9 0.1 7.2e-07 0.0018 252 317 .. 830 899 .. 818 899 .. 0.83 3 ! 30.6 0.7 1e-10 2.7e-07 252 364 .. 886 994 .. 881 1035 .. 0.81 4 ! 5.8 0.1 0.0035 8.9 250 309 .. 988 1047 .. 971 1054 .. 0.87 5 ! 10.7 0.0 0.00011 0.28 287 326 .. 1094 1133 .. 1078 1137 .. 0.87 6 ! 18.7 0.0 4.1e-07 0.0011 250 324 .. 1109 1182 .. 1103 1209 .. 0.84 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 3.1 Alsin_RLD 207 vlqlqqeeeeeekaslkslhsstserslaantrhllqqGyallntqlftlGasnkGll 264 +q+q e + +k+s+ ++s s++ +t + Gy l + + + G+ FUN_001102-T2 230 TVQMQLEYKSMHKTSSDQIRSC----SFSVTTSMAVAMGYEALSKRTIPMESVFSGMG 283 4444445555555555544443....45555555666777777666666666666655 PP == domain 2 score: 17.9 bits; conditional E-value: 7.2e-07 Alsin_RLD 252 qlftlGasnkGllGtGdhikrasv...arle..kldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlg 317 ++t G s +G lG Gd i + r+e ++++ v s+a+G eht++ dG +y wG + qlg FUN_001102-T2 830 DVYTWGKSQRGRLGHGDLIEEEGKsfpFRVEilHMHKINVLSVACGMEHTLALCWDG-VYSWGSSQYGQLG 899 689****************9764312256762255789*******************.7****99999987 PP == domain 3 score: 30.6 bits; conditional E-value: 1e-10 Alsin_RLD 252 qlftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlgn..ieelsspleislaeqllpveqvtalea 345 +++ G+s G lG Gd ++ + + + l + ++a+G+ h+++ ++d r++ wG + qlg ie++ p+ i +++ ++ + FUN_001102-T2 886 GVYSWGSSQYGQLGQGDTQQQTRPVYVTELSDKKCIAVACGHYHSLALSVDHRVWSWGWGVHGQLGVgsIEDVLLPTHI------AGLDEFEITQL 975 689**************************************************************94345666666555......55556666777 PP Alsin_RLD 346 tcGdyrtlllnaaGqiqel 364 + G ++ +l a+Gq+++ FUN_001102-T2 976 AAGYSHSAVLSAKGQVFTF 994 7888899999999999986 PP == domain 4 score: 5.8 bits; conditional E-value: 0.0035 Alsin_RLD 250 ntqlftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwG 309 + q+ft+G G lG G k+ + +e l + v i +G t++ t +++ wG FUN_001102-T2 988 KGQVFTFGGGLYGQLGLGTNCKQVVPQLVESLAKERVYLICCGSFETLAVTEGQKIFNWG 1047 569*******************9999999********************99999999999 PP == domain 5 score: 10.7 bits; conditional E-value: 0.00011 Alsin_RLD 287 csiaaGkehtvvrtldGrlyhwGlndkeqlgnieelsspl 326 + +G+ h +v G+ly wG+nd qlg +++ sp+ FUN_001102-T2 1094 NDVCCGNCHYLVLLESGQLYSWGFNDYGQLGLGNKMDSPM 1133 5677899999999999***************999999998 PP == domain 6 score: 18.7 bits; conditional E-value: 4.1e-07 Alsin_RLD 250 ntqlftlGasnkGllGtGdhikrasvarl.ekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlgnieelss 324 ql++ G ++ G lG G+++ rl +kl + + si++G e + + G +y wG d qlg e+ss FUN_001102-T2 1109 SGQLYSWGFNDYGQLGLGNKMDSPMTPRLiHKLANKHITSISVGAECSAAMDAAGLVYVWGRADSGQLG--LEFSS 1182 469******************9999888549**************************************..66665 PP >> Pep3_Vps18 Pep3/Vps18/deep orange beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.1 2.5e-07 0.00063 16 233 .. 57 305 .. 44 320 .. 0.70 2 ? -3.6 0.0 2.2 5.7e+03 49 75 .. 380 407 .. 366 415 .. 0.75 3 ? -1.8 0.0 0.63 1.6e+03 181 258 .. 555 639 .. 508 652 .. 0.68 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 2.5e-07 Pep3_Vps18 16 litslqVsnnvlvlalsngrllridLdnpedvdeielpkksseegkirkiFLdptgshllistnlgenyy..................lhtqskkp 93 ++ + n +vl ++ng ll+ +n ++ +++ ++ ++ir i Ldp+gs l+ ++ + +y+ ++ ++ FUN_001102-T2 57 VACHEDAKYNLIVLLCNNGSLLLKAEENGKSPVIKQVSWFQNPAKSIRAITLDPSGSWLMCACMDASLYIvpvagmvmvkpqvscsywATEDL-SL 151 556777788*******************99999888888888888********************999999****999988876654322222.23 PP Pep3_Vps18 94 kklsklkgvdIesVaWnkseatastreiLiGtadGkiyetelepseffkkeekyvkqvyklpekepitGlqfekvpesrrylvlvat...psrlyq 186 +k +g+ + V W+ + + + +iGt+ G+i ++l +v++++ ke+it l++ + ++++++++l++t ++ +q FUN_001102-T2 152 ILETKNRGLPSSVVWWH-TVDDLDIG--IIGTELGEILFVDLRL----------KVTVASVEAKESITSLKLMQDKQHETTALLINTvsgDTVQMQ 234 33334466655555554.33334444..**************64..........346788887788999987777644444444444232233455 PP Pep3_Vps18 187 fvgkvsskgseeeksl........................fsklFssykeeapkfqelpgelayselavsp 233 ++ k ++k+s+++ ++ ++++Fs + + + k++ +p +++ ++ ++s+ FUN_001102-T2 235 LEYKSMHKTSSDQIRScsfsvttsmavamgyealskrtipMESVFSGMGDLQDKIRPMPVTSSSGSTQFSV 305 55544444443333224545566666677766666666666999999999999999998877777777776 PP == domain 2 score: -3.6 bits; conditional E-value: 2.2 Pep3_Vps18 49 eielpkksseeg.kirkiFLdptgshll 75 ++++pk ++ + +i + FL p g++l+ FUN_001102-T2 380 SVSVPKGHQKMEsSIIQTFLLPAGEKLV 407 6777777765557999999999999886 PP == domain 3 score: -1.8 bits; conditional E-value: 0.63 Pep3_Vps18 181 psrlyqfvgkvsskgseeek.slfsklFssykeeapkfqel...pgelayselavsp.seekk...lpksfAwltssGiyhgklnf 258 + +l+ f+++v +++s+ k s +s+ Fs+ +++ ++ e+ + +la l+ ++ k+ +++++ +l ++G +h +l+ FUN_001102-T2 555 NLTLMCFIQQVLNSSSDAIKySELSDAFSQFLNDNFDYDEVtalE-QLAAYGLKGFMfDLAKArglMERALEILAQKGQFHLSLEL 639 457999999998887774333668888888887887777773322.2333333333322222257788888888888888888876 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.1 3.6e-07 0.00091 128 231 .. 137 244 .. 47 264 .. 0.80 2 ? -1.7 0.0 0.87 2.2e+03 15 83 .. 503 571 .. 492 604 .. 0.71 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 3.6e-07 Beta-prop_WDR36-Utp21_1st 128 kqGslqlwNirtgkliytfk..sfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDg...ep 206 q s w + +li ++k ++ s++ + ld+ ig++ Gei++++++ t+ +++++ +++ts+ +D+ + FUN_001102-T2 137 PQVSCSYWATEDLSLILETKnrGLPSSVVWWHTVDDLDIGIIGTELGEILFVDLRLKVTVASVEAK-ESITSLKLMQDKqheTT 219 5556667778888888888633556999999999******************************99.9**********844357 PP Beta-prop_WDR36-Utp21_1st 207 vlatgsssGdialwdLekrrlvhvl 231 l++ + sGd + Le ++++++ FUN_001102-T2 220 ALLINTVSGDTVQMQLEYKSMHKTS 244 999*********9999999877665 PP == domain 2 score: -1.7 bits; conditional E-value: 0.87 Beta-prop_WDR36-Utp21_1st 15 sklrllfvse.qlpekItalaadkdlvfaavgnkivvfkrgkevaellkeheekikkllvfgdhlvavde 83 + l+l +s+ +++++++++a ++ v +g+ v+++ v++ ++++ ++++ ++ ++++l + ++ FUN_001102-T2 503 RALELYHLSKcPFEKQVSQFAKHE-RVADILGHLRQVLNKHGDVHTAERKQLSNLTLMCFIQQVLNSSSD 571 458899999999999999887665.556666766667777777888888888888888888888877665 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.1 0.0 5e-05 0.13 43 111 .. 55 130 .. 39 147 .. 0.78 2 ? 1.2 0.2 0.11 2.8e+02 25 136 .. 144 257 .. 138 268 .. 0.62 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 5e-05 Beta-prop_EML_2 43 rsvafspdgk..llavGlkdGsvlvldaetl.....eevvevkdrkeaisdikfspdgklLavgshdnkiylYdvs 111 + va+++d k l+++ +++Gs+l+ +e++ ++v +++ ++i++i+ p+g++L +++ d ++y+ v+ FUN_001102-T2 55 QQVACHEDAKynLIVLLCNNGSLLLKAEENGkspviKQVSWFQNPAKSIRAITLDPSGSWLMCACMDASLYIVPVA 130 5566776665226888899****9998888621111455578999**************************98765 PP == domain 2 score: 1.2 bits; conditional E-value: 0.11 Beta-prop_EML_2 25 Wdlekkklvakvklekearsvafspdgkll...avGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskkyk 115 W +e+ +l+ ++k + +sv + + + l ++G++ G++l +d + l+++v+ + ke+i+ +k +d+++ + n++ +v+ +++ FUN_001102-T2 144 WATEDLSLILETKNRGLPSSVVWWHTVDDLdigIIGTELGEILFVDLR-LKVTVASVEAKESITSLKLMQDKQHETTALLINTVSGDTVQMQLE 236 566666666666555555555554433333112667788888888744.455555566788888888888887777777666666666666666 PP Beta-prop_EML_2 116 kvgklkghssfithlDwseds 136 ++ k +s+ i+++ +s FUN_001102-T2 237 YKSMHKTSSDQIRSCSFSVTT 257 666666677777777777554 PP >> RHG29_45_N Rho GTPase-activating protein 29/45 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.1 4.6e-05 0.12 31 66 .. 519 554 .. 500 587 .. 0.73 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 4.6e-05 RHG29_45_N 31 elrvvaherLgevLriLkavlekypaLnsteilsaa 66 + + her++++L L++vl+k+ +++ e + + FUN_001102-T2 519 VSQFAKHERVADILGHLRQVLNKHGDVHTAERKQLS 554 446678*********************998865544 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.00038 0.96 10 37 .. 99 126 .. 90 127 .. 0.84 2 ? -0.8 0.0 1.6 4.1e+03 11 25 .. 245 259 .. 237 264 .. 0.70 3 ? -3.4 0.1 10 2.6e+04 20 30 .. 435 445 .. 431 446 .. 0.83 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00038 WD40 10 HtsgVtslafspdgsllasgsdDgtvkl 37 +++++++ +p+gs+l ++++D ++++ FUN_001102-T2 99 PAKSIRAITLDPSGSWLMCACMDASLYI 126 5568*******************99986 PP == domain 2 score: -0.8 bits; conditional E-value: 1.6 WD40 11 tsgVtslafspdgsl 25 ++ ++s++fs + s+ FUN_001102-T2 245 SDQIRSCSFSVTTSM 259 344******988776 PP == domain 3 score: -3.4 bits; conditional E-value: 10 WD40 20 spdgsllasgs 30 s dg +l+++s FUN_001102-T2 435 SVDGVFLVTSS 445 67999***998 PP >> Znf_XAF1_N XIAP-associated factor 1-like, N-terminal zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.2 0.01 26 9 17 .. 1006 1014 .. 1006 1016 .. 0.91 2 ? 4.0 0.3 0.018 46 4 15 .. 1094 1105 .. 1091 1109 .. 0.85 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.01 Znf_XAF1_N 9 kNCkqwvPk 17 +NCkq+vP+ FUN_001102-T2 1006 TNCKQVVPQ 1014 6*******7 PP == domain 2 score: 4.0 bits; conditional E-value: 0.018 Znf_XAF1_N 4 devqCkNCkqwv 15 ++v C NC+ v FUN_001102-T2 1094 NDVCCGNCHYLV 1105 7999*****776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1276 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 838 (0.0328049); expected 510.9 (0.02) Passed bias filter: 709 (0.0277549); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.46u 0.43s 00:00:00.89 Elapsed: 00:00:00.43 # Mc/sec: 11968.28 // Query: FUN_001103-T1 [L=301] Description: FUN_001103 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (301 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 996 (0.03899); expected 510.9 (0.02) Passed bias filter: 865 (0.0338618); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 2927.80 // Query: FUN_001104-T1 [L=142] Description: FUN_001104 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-06 26.1 4.2 33 4.9 0.0 6.5 7 Herpes_US9 Alphaherpesvirus tegument protein US9 0.0023 18.2 0.0 1.9e+02 2.6 0.0 5.4 6 RHH_1 Ribbon-helix-helix protein, copG family ------ inclusion threshold ------ 0.037 14.4 8.5 75 3.8 0.1 6.2 7 PRM_STIL Proline-rich motif in STIL 0.068 13.5 3.8 1.3e+02 3.1 0.1 5.0 6 MLLE_2 MLLE-related domain 0.11 12.7 0.0 3.6e+02 1.4 0.0 4.8 6 RPA_interact_N Replication protein A interacting N-terminal 0.25 11.8 0.0 2.1e+02 2.5 0.0 4.5 6 TehB-like TehB-like domain 0.44 11.5 5.3 78 4.3 0.0 5.5 7 DUF5428 Family of unknown function (DUF5428) 0.53 9.5 1.2 64 2.6 0.0 3.6 6 AftA_N Arabinofuranosyltransferase N terminal Domain annotation for each model (and alignments): >> Herpes_US9 Alphaherpesvirus tegument protein US9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.01 33 12 26 .. 11 25 .. 7 27 .. 0.83 2 ? 3.4 0.0 0.03 97 12 20 .. 27 35 .. 24 42 .. 0.86 3 ? 4.4 0.1 0.016 50 12 25 .. 43 56 .. 39 65 .. 0.81 4 ? 0.8 0.1 0.2 6.4e+02 12 20 .. 59 67 .. 56 74 .. 0.85 5 ? 3.5 0.0 0.03 95 12 19 .. 75 82 .. 71 90 .. 0.87 6 ? 4.1 0.1 0.019 62 12 21 .. 91 100 .. 86 112 .. 0.83 7 ? 0.6 0.0 0.23 7.4e+02 12 19 .. 107 114 .. 100 118 .. 0.90 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.01 Herpes_US9 12 deFLvRiGkyqsklr 26 d+FL R+G k+ FUN_001104-T1 11 DDFLTRMGPSGPKIF 25 9*******8777776 PP == domain 2 score: 3.4 bits; conditional E-value: 0.03 Herpes_US9 12 deFLvRiGk 20 d+FL R+G FUN_001104-T1 27 DDFLTRMGP 35 9******95 PP == domain 3 score: 4.4 bits; conditional E-value: 0.016 Herpes_US9 12 deFLvRiGkyqskl 25 d+FL R+G k+ FUN_001104-T1 43 DDFLTRMGPSVPKM 56 9*******766555 PP == domain 4 score: 0.8 bits; conditional E-value: 0.2 Herpes_US9 12 deFLvRiGk 20 d+F R+G FUN_001104-T1 59 DDFFTRMGP 67 8******95 PP == domain 5 score: 3.5 bits; conditional E-value: 0.03 Herpes_US9 12 deFLvRiG 19 d+FL R+G FUN_001104-T1 75 DDFLTRMG 82 9******9 PP == domain 6 score: 4.1 bits; conditional E-value: 0.019 Herpes_US9 12 deFLvRiGky 21 d+FL R+G FUN_001104-T1 91 DDFLTRMGPS 100 9*******65 PP == domain 7 score: 0.6 bits; conditional E-value: 0.23 Herpes_US9 12 deFLvRiG 19 d+F R+G FUN_001104-T1 107 DDFFTRMG 114 9******9 PP >> RHH_1 Ribbon-helix-helix protein, copG family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.22 6.9e+02 22 32 .. 1 11 [. 1 11 [. 0.90 2 ? 2.5 0.0 0.065 2.1e+02 21 32 .. 32 43 .. 31 43 .. 0.92 3 ? -1.1 0.0 0.89 2.8e+03 21 32 .. 48 59 .. 47 59 .. 0.90 4 ? 2.5 0.0 0.065 2.1e+02 21 32 .. 64 75 .. 63 75 .. 0.92 5 ? 0.7 0.0 0.25 7.9e+02 21 32 .. 80 91 .. 79 91 .. 0.91 6 ? 2.6 0.0 0.059 1.9e+02 21 32 .. 96 107 .. 95 107 .. 0.92 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.22 RHH_1 22 rgrSrSelIRe 32 +g+S+ e++R+ FUN_001104-T1 1 MGPSVPEILRD 11 599*******7 PP == domain 2 score: 2.5 bits; conditional E-value: 0.065 RHH_1 21 argrSrSelIRe 32 ++g+S+ e++R+ FUN_001104-T1 32 RMGPSVPEILRD 43 789********7 PP == domain 3 score: -1.1 bits; conditional E-value: 0.89 RHH_1 21 argrSrSelIRe 32 ++g+S+ ++R+ FUN_001104-T1 48 RMGPSVPKMFRD 59 789*******96 PP == domain 4 score: 2.5 bits; conditional E-value: 0.065 RHH_1 21 argrSrSelIRe 32 ++g+S+ e++R+ FUN_001104-T1 64 RMGPSVPEILRD 75 789********7 PP == domain 5 score: 0.7 bits; conditional E-value: 0.25 RHH_1 21 argrSrSelIRe 32 ++g+S+ +++R+ FUN_001104-T1 80 RMGPSVPDILRD 91 789********7 PP == domain 6 score: 2.6 bits; conditional E-value: 0.059 RHH_1 21 argrSrSelIRe 32 ++g+S+ e++R+ FUN_001104-T1 96 RMGPSVPEIFRD 107 789********7 PP >> PRM_STIL Proline-rich motif in STIL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.2 0.18 5.8e+02 41 46 .. 3 8 .. 1 10 [. 0.86 2 ? 3.8 0.1 0.024 75 37 46 .. 31 40 .. 8 41 .. 0.83 3 ? -0.1 0.0 0.41 1.3e+03 37 45 .. 47 55 .. 43 57 .. 0.83 4 ? 3.2 0.0 0.036 1.2e+02 37 46 .. 63 72 .. 58 73 .. 0.87 5 ? 0.6 0.0 0.24 7.8e+02 37 46 .. 79 88 .. 75 93 .. 0.86 6 ? 3.4 0.1 0.033 1.1e+02 37 46 .. 95 104 .. 89 105 .. 0.87 7 ? -0.8 0.0 0.65 2.1e+03 38 45 .. 112 119 .. 110 122 .. 0.81 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.18 PRM_STIL 41 PsVPEl 46 PsVPE+ FUN_001104-T1 3 PSVPEI 8 *****7 PP == domain 2 score: 3.8 bits; conditional E-value: 0.024 PRM_STIL 37 rriqPsVPEl 46 +r+ PsVPE+ FUN_001104-T1 31 TRMGPSVPEI 40 6899*****6 PP == domain 3 score: -0.1 bits; conditional E-value: 0.41 PRM_STIL 37 rriqPsVPE 45 +r+ PsVP FUN_001104-T1 47 TRMGPSVPK 55 5789****6 PP == domain 4 score: 3.2 bits; conditional E-value: 0.036 PRM_STIL 37 rriqPsVPEl 46 +r+ PsVPE+ FUN_001104-T1 63 TRMGPSVPEI 72 5789*****6 PP == domain 5 score: 0.6 bits; conditional E-value: 0.24 PRM_STIL 37 rriqPsVPEl 46 +r+ PsVP++ FUN_001104-T1 79 TRMGPSVPDI 88 5889****85 PP == domain 6 score: 3.4 bits; conditional E-value: 0.033 PRM_STIL 37 rriqPsVPEl 46 +r+ PsVPE+ FUN_001104-T1 95 TRMGPSVPEI 104 6889*****7 PP == domain 7 score: -0.8 bits; conditional E-value: 0.65 PRM_STIL 38 riqPsVPE 45 r+ PsVP FUN_001104-T1 112 RMGPSVPK 119 788***95 PP >> MLLE_2 MLLE-related domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.047 1.5e+02 43 55 .. 5 17 .. 1 21 [. 0.89 2 ? -2.0 0.0 1.6 5e+03 44 55 .. 22 33 .. 22 37 .. 0.89 3 ? 3.1 0.1 0.04 1.3e+02 43 55 .. 37 49 .. 31 55 .. 0.88 4 ? 3.0 0.1 0.043 1.4e+02 43 55 .. 69 81 .. 62 84 .. 0.88 5 ? 1.0 0.0 0.17 5.5e+02 43 55 .. 85 97 .. 81 101 .. 0.89 6 ? -0.5 0.0 0.53 1.7e+03 43 55 .. 101 113 .. 96 114 .. 0.85 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.047 MLLE_2 43 LPetLrRefilnm 55 Pe+Lr +f+ +m FUN_001104-T1 5 VPEILRDDFLTRM 17 6*********998 PP == domain 2 score: -2.0 bits; conditional E-value: 1.6 MLLE_2 44 PetLrRefilnm 55 P+++r +f+ +m FUN_001104-T1 22 PKIFRDDFLTRM 33 899999999988 PP == domain 3 score: 3.1 bits; conditional E-value: 0.04 MLLE_2 43 LPetLrRefilnm 55 Pe+Lr +f+ +m FUN_001104-T1 37 VPEILRDDFLTRM 49 7*********998 PP == domain 4 score: 3.0 bits; conditional E-value: 0.043 MLLE_2 43 LPetLrRefilnm 55 Pe+Lr +f+ +m FUN_001104-T1 69 VPEILRDDFLTRM 81 7********9998 PP == domain 5 score: 1.0 bits; conditional E-value: 0.17 MLLE_2 43 LPetLrRefilnm 55 P++Lr +f+ +m FUN_001104-T1 85 VPDILRDDFLTRM 97 69*******9998 PP == domain 6 score: -0.5 bits; conditional E-value: 0.53 MLLE_2 43 LPetLrRefilnm 55 Pe++r +f +m FUN_001104-T1 101 VPEIFRDDFFTRM 113 79******99887 PP >> RPA_interact_N Replication protein A interacting N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.17 5.4e+02 15 25 .. 7 17 .. 3 17 .. 0.90 2 ? -1.7 0.0 1.1 3.4e+03 16 25 .. 24 33 .. 23 33 .. 0.84 3 ? 1.0 0.0 0.16 5e+02 15 25 .. 39 49 .. 34 49 .. 0.89 4 ? 1.4 0.0 0.11 3.6e+02 15 25 .. 71 81 .. 58 81 .. 0.85 5 ? 0.3 0.0 0.26 8.3e+02 15 25 .. 87 97 .. 83 97 .. 0.89 6 ? -0.2 0.0 0.37 1.2e+03 15 25 .. 103 113 .. 99 113 .. 0.89 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.17 RPA_interact_N 15 etLRerCleRl 25 e+LR + l R+ FUN_001104-T1 7 EILRDDFLTRM 17 89*******98 PP == domain 2 score: -1.7 bits; conditional E-value: 1.1 RPA_interact_N 16 tLRerCleRl 25 ++R + l R+ FUN_001104-T1 24 IFRDDFLTRM 33 6899999998 PP == domain 3 score: 1.0 bits; conditional E-value: 0.16 RPA_interact_N 15 etLRerCleRl 25 e+LR + l R+ FUN_001104-T1 39 EILRDDFLTRM 49 89*******98 PP == domain 4 score: 1.4 bits; conditional E-value: 0.11 RPA_interact_N 15 etLRerCleRl 25 e+LR + l R+ FUN_001104-T1 71 EILRDDFLTRM 81 89******998 PP == domain 5 score: 0.3 bits; conditional E-value: 0.26 RPA_interact_N 15 etLRerCleRl 25 ++LR + l R+ FUN_001104-T1 87 DILRDDFLTRM 97 79******998 PP == domain 6 score: -0.2 bits; conditional E-value: 0.37 RPA_interact_N 15 etLRerCleRl 25 e++R + + R+ FUN_001104-T1 103 EIFRDDFFTRM 113 89******998 PP >> TehB-like TehB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.42 1.3e+03 10 24 .. 4 18 .. 2 21 .. 0.90 2 ? -0.2 0.0 0.44 1.4e+03 10 24 .. 36 50 .. 33 51 .. 0.90 3 ? 2.5 0.0 0.066 2.1e+02 10 24 .. 52 66 .. 48 67 .. 0.91 4 ? -0.2 0.0 0.43 1.4e+03 10 24 .. 68 82 .. 66 85 .. 0.90 5 ? -1.2 0.0 0.91 2.9e+03 10 24 .. 84 98 .. 82 100 .. 0.89 6 ? 0.5 0.0 0.27 8.7e+02 10 24 .. 100 114 .. 97 115 .. 0.90 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.42 TehB-like 10 tiPaallekHnTkaG 24 ++P+ l++++ T+ G FUN_001104-T1 4 SVPEILRDDFLTRMG 18 79********99987 PP == domain 2 score: -0.2 bits; conditional E-value: 0.44 TehB-like 10 tiPaallekHnTkaG 24 ++P+ l++++ T+ G FUN_001104-T1 36 SVPEILRDDFLTRMG 50 79********99987 PP == domain 3 score: 2.5 bits; conditional E-value: 0.066 TehB-like 10 tiPaallekHnTkaG 24 ++P+++++++ T+ G FUN_001104-T1 52 SVPKMFRDDFFTRMG 66 79**********987 PP == domain 4 score: -0.2 bits; conditional E-value: 0.43 TehB-like 10 tiPaallekHnTkaG 24 ++P+ l++++ T+ G FUN_001104-T1 68 SVPEILRDDFLTRMG 82 79********99987 PP == domain 5 score: -1.2 bits; conditional E-value: 0.91 TehB-like 10 tiPaallekHnTkaG 24 ++P+ l++++ T+ G FUN_001104-T1 84 SVPDILRDDFLTRMG 98 79********99987 PP == domain 6 score: 0.5 bits; conditional E-value: 0.27 TehB-like 10 tiPaallekHnTkaG 24 ++P+ +++++ T+ G FUN_001104-T1 100 SVPEIFRDDFFTRMG 114 79**********987 PP >> DUF5428 Family of unknown function (DUF5428) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 4.6 1.5e+04 37 45 .. 12 20 .. 11 20 .. 0.82 2 ? 0.2 0.0 0.47 1.5e+03 37 46 .. 28 37 .. 26 39 .. 0.85 3 ? 0.4 0.0 0.41 1.3e+03 37 46 .. 44 53 .. 42 56 .. 0.84 4 ? 0.0 0.0 0.53 1.7e+03 37 46 .. 60 69 .. 58 71 .. 0.85 5 ? 0.2 0.0 0.48 1.5e+03 37 46 .. 76 85 .. 74 87 .. 0.86 6 ? 0.2 0.0 0.47 1.5e+03 37 46 .. 92 101 .. 90 103 .. 0.85 7 ? 4.3 0.0 0.024 78 37 52 .. 108 125 .. 106 130 .. 0.79 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 4.6 DUF5428 37 DvKkdlGPs 45 D+ +GPs FUN_001104-T1 12 DFLTRMGPS 20 777889**8 PP == domain 2 score: 0.2 bits; conditional E-value: 0.47 DUF5428 37 DvKkdlGPsv 46 D+ +GPsv FUN_001104-T1 28 DFLTRMGPSV 37 78889****9 PP == domain 3 score: 0.4 bits; conditional E-value: 0.41 DUF5428 37 DvKkdlGPsv 46 D+ +GPsv FUN_001104-T1 44 DFLTRMGPSV 53 78889****9 PP == domain 4 score: 0.0 bits; conditional E-value: 0.53 DUF5428 37 DvKkdlGPsv 46 D+ +GPsv FUN_001104-T1 60 DFFTRMGPSV 69 77889****9 PP == domain 5 score: 0.2 bits; conditional E-value: 0.48 DUF5428 37 DvKkdlGPsv 46 D+ +GPsv FUN_001104-T1 76 DFLTRMGPSV 85 78889****9 PP == domain 6 score: 0.2 bits; conditional E-value: 0.47 DUF5428 37 DvKkdlGPsv 46 D+ +GPsv FUN_001104-T1 92 DFLTRMGPSV 101 78889****9 PP == domain 7 score: 4.3 bits; conditional E-value: 0.024 DUF5428 37 DvKkdlGPsvSmTVV..G 52 D+ +GPsv T V G FUN_001104-T1 108 DFFTRMGPSVPKTCVpgG 125 77889******9998545 PP >> AftA_N Arabinofuranosyltransferase N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 0.31 1e+03 94 110 .. 2 18 .. 1 27 [. 0.85 2 ? 0.3 0.0 0.099 3.2e+02 100 112 .. 24 36 .. 14 43 .. 0.85 3 ? 2.6 0.0 0.02 64 94 112 .. 50 68 .. 45 75 .. 0.87 4 ? -0.9 0.0 0.24 7.6e+02 94 112 .. 66 84 .. 65 91 .. 0.84 5 ? -0.7 0.0 0.2 6.5e+02 94 112 .. 82 100 .. 78 109 .. 0.85 6 ? 1.5 0.0 0.042 1.4e+02 94 111 .. 98 115 .. 93 119 .. 0.86 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.31 AftA_N 94 GisvDqeFRtqyLtrlt 110 G sv + R ++Ltr+ FUN_001104-T1 2 GPSVPEILRDDFLTRMG 18 66888899*******97 PP == domain 2 score: 0.3 bits; conditional E-value: 0.099 AftA_N 100 eFRtqyLtrltds 112 FR ++Ltr+ s FUN_001104-T1 24 IFRDDFLTRMGPS 36 6*********865 PP == domain 3 score: 2.6 bits; conditional E-value: 0.02 AftA_N 94 GisvDqeFRtqyLtrltds 112 G sv + FR +++tr+ s FUN_001104-T1 50 GPSVPKMFRDDFFTRMGPS 68 78999***********865 PP == domain 4 score: -0.9 bits; conditional E-value: 0.24 AftA_N 94 GisvDqeFRtqyLtrltds 112 G sv + R ++Ltr+ s FUN_001104-T1 66 GPSVPEILRDDFLTRMGPS 84 66888899********865 PP == domain 5 score: -0.7 bits; conditional E-value: 0.2 AftA_N 94 GisvDqeFRtqyLtrltds 112 G sv + R ++Ltr+ s FUN_001104-T1 82 GPSVPDILRDDFLTRMGPS 100 67888999********865 PP == domain 6 score: 1.5 bits; conditional E-value: 0.042 AftA_N 94 GisvDqeFRtqyLtrltd 111 G sv + FR +++tr+ FUN_001104-T1 98 GPSVPEIFRDDFFTRMGP 115 779999**********76 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 109 (0.00426698); expected 510.9 (0.02) Passed bias filter: 107 (0.00418869); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1424.01 // Query: FUN_001105-T1 [L=450] Description: FUN_001105 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.9e-17 61.7 54.4 1.4e-06 28.9 7.9 5.1 5 EGF EGF-like domain 3.5e-14 53.9 0.3 3.5e-14 53.9 0.3 2.1 2 Lectin_C Lectin C-type domain 3.8e-10 40.5 2.6 7.7e-10 39.4 2.6 1.6 1 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal gl 5.4e-10 39.8 50.5 0.00012 22.9 7.3 6.5 6 hEGF Human growth factor-like EGF 1.7e-06 28.3 41.1 1.7e-06 28.3 41.1 2.5 2 EGF_TEN Teneurin EGF domain ------ inclusion threshold ------ 0.01 16.7 10.0 0.01 16.7 10.0 5.0 5 EGF_2 EGF-like domain Domain annotation for each model (and alignments): >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 1.9 3.5 1.5e+04 6 22 .. 90 95 .. 86 98 .. 0.58 2 ! 28.9 7.9 3.4e-10 1.4e-06 1 31 [. 102 131 .. 102 132 .. 0.92 3 ! 25.7 10.7 3.4e-09 1.4e-05 1 32 [] 139 169 .. 139 169 .. 0.96 4 ! 28.1 7.7 5.9e-10 2.5e-06 1 30 [. 176 204 .. 176 206 .. 0.91 5 ? -1.5 0.0 1.1 4.6e+03 16 22 .. 401 407 .. 398 408 .. 0.74 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 3.5 EGF 6 CsngGtCvdtprggytC 22 C+ +ytC FUN_001105-T1 90 CH-----------HYTC 95 44...........4555 PP == domain 2 score: 28.9 bits; conditional E-value: 3.4e-10 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 Cs+ pC+ngGtCv++ +++CiCp+ +Gk FUN_001105-T1 102 CSSSPCLNGGTCVNGK-RTFSCICPPTHKGK 131 9***************.********966666 PP == domain 3 score: 25.7 bits; conditional E-value: 3.4e-09 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 Cs+ pC+ngGtC+d+ + +tC Cp +y G r FUN_001105-T1 139 CSSSPCMNGGTCRDGA-NNFTCSCPYPYYGQR 169 9***************.***********9976 PP == domain 4 score: 28.1 bits; conditional E-value: 5.9e-10 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytG 30 C++npC+ngGtC+d + +tC+C+ y+G FUN_001105-T1 176 CHSNPCQNGGTCMDAL-HNFTCTCTSVYAG 204 ****************.*******875555 PP == domain 5 score: -1.5 bits; conditional E-value: 1.1 EGF 16 prggytC 22 ++ggy+C FUN_001105-T1 401 GGGGYSC 407 459**** PP >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.9 0.3 8.1e-18 3.5e-14 11 107 .] 2 97 .. 1 97 [. 0.95 2 ? -2.7 0.2 3.2 1.4e+04 63 75 .. 259 272 .. 236 288 .. 0.52 Alignments for each domain: == domain 1 score: 53.9 bits; conditional E-value: 8.1e-18 Lectin_C 11 lCqkeggkLvsinskeenkflssllkksnkkfWigltdeksegtwkwedgskvnteeytnw..epnnngenedCvel..ekssgkwndesCnsknp 102 +C+ g++L++++s+een ++++ + +++Wigl+d +eg ++w+dg + + ++ w ++ n+ + edCv+ wnd++C+ + FUN_001105-T1 2 MCRAFGASLTAVESQEENVYIQHRH--NGDRAWIGLNDIATEGLFSWVDGCPFR---FRYWapNQPNDFRGEDCVHTlgVGHGYMWNDVDCSICHH 92 7***********************5..***************************...888999888999********98788889*********** PP Lectin_C 103 fvCek 107 + C+k FUN_001105-T1 93 YTCKK 97 ***96 PP == domain 2 score: -2.7 bits; conditional E-value: 3.2 Lectin_C 63 vnteeytnw...epnn 75 + + nw n+ FUN_001105-T1 259 N--ADSANWmqySGNW 272 2..2333443333333 PP >> Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.4 2.6 1.8e-13 7.7e-10 3 133 .. 213 363 .. 211 397 .. 0.73 Alignments for each domain: == domain 1 score: 39.4 bits; conditional E-value: 1.8e-13 Fibrinogen_C 3 rdCedaakkGaktsglytitldkakkalevyCdmetdggGWtvlqkrldG.stnfkr...e.WkdykaGfGnlsk.........eefWLGndkihk 84 C++ ++ G +tsg+y ++ ++ +++vyCdm+++ggGWt++ + + s n+++ + W d + +G ++ fWL + + + FUN_001105-T1 213 SSCKNLYRWGIRTSGIYYLNVSGT--TFQVYCDMTSSGGGWTLISRFSNAdSANWMQysgNwWYDKTSSYGSITSpssnsdmisPAFWLVQGNDIR 306 67***************9988877..9*****************998876245555422243678889999999899999999999***9888889 PP Fibrinogen_C 85 ltkqgeyklridledf..ng...etvfalydsf...kvanekekyrLkvenykGdag 133 +t++++++ ++ g + +a +++f ++ n ++ +r ++ y G g FUN_001105-T1 307 ITRSDDVSTYVETYGNciGGrsfRRFMASFGNFrygTIWNSNSCHRSCYARYGGIIG 363 999999988887542211221113455666666333355666666666666666444 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 1.0 3.4 1.4e+04 7 16 .. 90 95 .. 89 96 .. 0.69 2 ! 22.1 4.9 4.9e-08 0.00021 1 20 [. 107 126 .. 107 127 .. 0.98 3 ! 22.9 7.3 2.8e-08 0.00012 1 19 [. 144 162 .. 144 163 .. 0.98 4 ! 18.0 5.1 9.3e-07 0.004 1 19 [. 181 199 .. 181 200 .. 0.96 5 ? -3.1 0.1 4.3 1.8e+04 7 16 .. 207 215 .. 205 216 .. 0.79 6 ? 0.2 0.1 0.39 1.7e+03 10 17 .. 401 408 .. 393 408 .. 0.81 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 3.4 hEGF 7 CvdgvngykC 16 C+ +y+C FUN_001105-T1 90 CH----HYTC 95 66....7888 PP == domain 2 score: 22.1 bits; conditional E-value: 4.9e-08 hEGF 1 ClNGGtCvdgvngykCqCpp 20 ClNGGtCv+g ++C+Cpp FUN_001105-T1 107 CLNGGTCVNGKRTFSCICPP 126 *******************9 PP == domain 3 score: 22.9 bits; conditional E-value: 2.8e-08 hEGF 1 ClNGGtCvdgvngykCqCp 19 C+NGGtC dg+n ++C+Cp FUN_001105-T1 144 CMNGGTCRDGANNFTCSCP 162 ******************9 PP == domain 4 score: 18.0 bits; conditional E-value: 9.3e-07 hEGF 1 ClNGGtCvdgvngykCqCp 19 C+NGGtC d ++C C FUN_001105-T1 181 CQNGGTCMDALHNFTCTCT 199 ******************5 PP == domain 5 score: -3.1 bits; conditional E-value: 4.3 hEGF 7 CvdgvngykC 16 C +v++ +C FUN_001105-T1 207 CEVLVGS-SC 215 8888888.88 PP == domain 6 score: 0.2 bits; conditional E-value: 0.39 hEGF 10 gvngykCq 17 g++gy+C+ FUN_001105-T1 401 GGGGYSCS 408 7899***5 PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 41.1 4e-10 1.7e-06 19 166 .. 64 215 .. 60 218 .. 0.80 2 ? -3.0 0.3 1.5 6.4e+03 193 199 .. 350 356 .. 341 394 .. 0.53 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 4e-10 EGF_TEN 19 gfeGeDCskavcpvlCsgrGaye.kgkCeCeegykGeeCevkvkeceaancsgrGeciegk....CvCkpgykGkkCee.ktcldanCsgngvCvn 108 f+GeDC ++ l g+G + + C + y C+ ++ec+++ c + G+c++gk C+C p++kGk+Cee +c+++ C + g+C + FUN_001105-T1 64 DFRGEDCVHT----LGVGHGYMWnDVDCSICHHY---TCKKDFDECSSSPCLNGGTCVNGKrtfsCICPPTHKGKTCEEfDECSSSPCMNGGTCRD 152 6899999765....55699977624456555555...69******************99744444************98468************98 PP EGF_TEN 109 g....kCvCeegytgedCelekkackekcskkgklvke..sgscvcdegytgedceeetcsldC 166 g +C C y+g+ C+ + ++ c++ g+++++ + +c+c + y+g+ ce + s +C FUN_001105-T1 153 GannfTCSCPYPYYGQRCQDFDDCHSNPCQNGGTCMDAlhNFTCTCTSVYAGQLCEVLVGS-SC 215 744447**************99888899999999985422778***********9976443.45 PP == domain 2 score: -3.0 bits; conditional E-value: 1.5 EGF_TEN 193 CesrCke 199 C+++C + FUN_001105-T1 350 CHRSCYA 356 2222221 PP >> EGF_2 EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.7 6 2.6e+04 5 9 .. 87 91 .. 85 97 .. 0.57 2 ? 16.7 10.0 2.4e-06 0.01 1 32 [] 102 133 .. 102 133 .. 0.90 3 ? 7.7 12.1 0.0015 6.6 1 32 [] 139 170 .. 139 170 .. 0.80 4 ? 11.8 9.3 7.8e-05 0.33 1 32 [] 176 207 .. 176 207 .. 0.88 5 ? -3.2 0.8 3.9 1.7e+04 26 32 .] 431 437 .. 425 438 .. 0.47 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 6 EGF_2 5 gliCs 9 ++iC+ FUN_001105-T1 87 CSICH 91 44565 PP == domain 2 score: 16.7 bits; conditional E-value: 2.4e-06 EGF_2 1 CsasgliCsgrGtCvnqcGk....CkCdsgyqGatC 32 Cs+ + C ++GtCv +Gk C C++ + G+tC FUN_001105-T1 102 CSS--SPCLNGGTCV--NGKrtfsCICPPTHKGKTC 133 775..48********..**77888************ PP == domain 3 score: 7.7 bits; conditional E-value: 0.0015 EGF_2 1 CsasgliCsgrGtC.vnqcG.kCkCdsgyqGatC 32 Cs+ + C ++GtC + +++ +C+C+ y+G C FUN_001105-T1 139 CSS--SPCMNGGTCrDGANNfTCSCPYPYYGQRC 170 775..48*******55555455**********99 PP == domain 4 score: 11.8 bits; conditional E-value: 7.8e-05 EGF_2 1 CsasgliCsgrGtC.vnqcGk.CkCdsgyqGatC 32 C+ ++ C+++GtC + ++ C C s y G C FUN_001105-T1 176 CH--SNPCQNGGTCmDALHNFtCTCTSVYAGQLC 207 77..569*******99999745**********99 PP == domain 5 score: -3.2 bits; conditional E-value: 3.9 EGF_2 26 gyqGatC 32 g +G +C FUN_001105-T1 431 GDFGEHC 437 2334444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (450 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 778 (0.0304561); expected 510.9 (0.02) Passed bias filter: 258 (0.0100998); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 4509.75 // Query: FUN_001106-T1 [L=681] Description: FUN_001106 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.8e-17 61.3 10.5 0.003 18.1 0.0 6.5 6 H_lectin H-type lectin domain 1.2e-09 38.6 6.1 3e-09 37.3 6.1 1.7 1 Kazal_2 Kazal-type serine protease inhibitor domain 1.8e-05 25.1 6.7 6.1e-05 23.4 6.7 1.9 1 Kazal_1 Kazal-type serine protease inhibitor domain ------ inclusion threshold ------ 0.053 14.4 2.1 0.14 13.0 2.1 1.7 1 Kazal_CFAI Complement factor I, KAZAL domain 0.068 13.4 0.1 16 5.7 0.0 2.3 2 WHD_TANC1 TANC1-like, winged helix-turn-helix domain Domain annotation for each model (and alignments): >> H_lectin H-type lectin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.18 9e+02 35 67 .] 85 117 .. 52 117 .. 0.72 2 ! 10.7 0.0 0.00012 0.61 3 67 .] 142 207 .. 141 207 .. 0.87 3 ! 15.7 0.1 3.3e-06 0.017 5 48 .. 241 290 .. 238 299 .. 0.81 4 ? 0.2 0.1 0.23 1.2e+03 16 54 .. 425 465 .. 422 482 .. 0.67 5 ! 16.0 0.0 2.7e-06 0.014 9 67 .] 514 573 .. 513 573 .. 0.84 6 ! 18.1 0.0 5.9e-07 0.003 3 63 .. 606 669 .. 605 672 .. 0.81 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.18 H_lectin 35 vsasnitttgFtlkfetwgdtrlyslrvswlAi 67 v++ +t+ F + + g + s+ v+w+A+ FUN_001106-T1 85 VWTAEVTRYNFRVCVLESGPGTNGSFVVNWIAF 117 445566777777777667777777777788876 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00012 H_lectin 3 tvtFskpFespPqVilslnsldldkgknlr.fkvsasnitttgFtlkfetw..gdtrlyslrvswlAi 67 +++F + F s+P V+ ++ + + +++ + + + ++ F + ++ d + ++++v+w+A+ FUN_001106-T1 142 RIDFVQRFHSVPYVLATVRHGGITG--PQDaMNMWLEEKQEDHFRICIREVktFDGKHQNIQVDWVAF 207 799*******************877..4455999999999******99655336*************8 PP == domain 3 score: 15.7 bits; conditional E-value: 3.3e-06 H_lectin 5 tFskpFespPqVilslnsldldk......gknlrfkvsasnitttgFtlk 48 +F k+F pP Vi+++n++ + n+ ++++++ it ++F + FUN_001106-T1 241 NFTKEFYAPPVVIVTVNHFYNNRnlysvkPENNALNTWIEEITISSFRVC 290 8*******************755555554444559999999999999875 PP == domain 4 score: 0.2 bits; conditional E-value: 0.23 H_lectin 16 Vilslnsldldkgknlr..fkvsasnitttgFtlkfetwgd 54 + +s+n+++++ + + + +++++i + Ft+ +++ g FUN_001106-T1 425 IQVSINHVNFSDPSYVHdaVVAWVEDILDNNFTVCVTQAGR 465 56888888887766666688889999999999988876653 PP == domain 5 score: 16.0 bits; conditional E-value: 2.7e-06 H_lectin 9 pFespPqVilslnsldldkgknlr.fkvsasnitttgFtlkfetw..gdtrlyslrvswlAi 67 +F+s P+V++s ++ + ++ +v+ +++ttt+F++ + d ++++++wlA+ FUN_001106-T1 514 KFQSLPTVLVSAEHERRSL--LHDaSSVWLEDVTTTSFKICARELqnFDGAHQNIHIDWLAF 573 6999999999999988444..333699*************998774349************8 PP == domain 6 score: 18.1 bits; conditional E-value: 5.9e-07 H_lectin 3 tvtFskpFespPqVilslnsldldkgknlr.....fkvsasnitttgFtlkfetwgdtrlyslrvs 63 +v F+kp++ P+V++s n+ +g+nl+ ++++++ i++tgF + ++ ++ l++s FUN_001106-T1 606 DVLFKKPYNDSPEVLVSANHST--NGRNLNplynaISAWVEYINQTGFRACVKEVFVQQHDPLSIS 669 689*****************99..66666666789*************988776666665555555 PP >> Kazal_2 Kazal-type serine protease inhibitor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.3 6.1 5.8e-13 3e-09 2 48 .] 340 384 .. 339 384 .. 0.95 Alignments for each domain: == domain 1 score: 37.3 bits; conditional E-value: 5.8e-13 Kazal_2 2 cncsCpkaeyepVCGsDgvtYaseCeLeaagCklgkklkkvkhdGsC 48 c +Cp ++ epVC s+g tY++ C+++++ C l+ + + ++h G C FUN_001106-T1 340 CVDNCP-SYEEPVCSSNGTTYDNVCVFQREMCHLKANFS-LYHPGDC 384 6679**.8888****************************.*****99 PP >> Kazal_1 Kazal-type serine protease inhibitor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 6.7 1.2e-08 6.1e-05 8 49 .] 343 384 .. 332 384 .. 0.87 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 1.2e-08 Kazal_1 8 aCpreydpvCGtDgkTYsneCllCaengkkgtklqlekdGeC 49 Cp +pvC+++g TY+n C++ e +++++l + G C FUN_001106-T1 343 NCPSYEEPVCSSNGTTYDNVCVFQREMCHLKANFSLYHPGDC 384 3**********************7777788888888888888 PP >> Kazal_CFAI Complement factor I, KAZAL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 2.1 2.7e-05 0.14 7 37 .. 344 374 .. 342 384 .. 0.79 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2.7e-05 Kazal_CFAI 7 CpknGtsvCstngrsfrtyCqlksyeCrrkk 37 Cp ++vCs ng ++ + C + C k FUN_001106-T1 344 CPSYEEPVCSSNGTTYDNVCVFQREMCHLKA 374 99999***************99998886543 PP >> WHD_TANC1 TANC1-like, winged helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.0031 16 41 94 .. 138 189 .. 128 192 .. 0.87 2 ? 5.1 0.0 0.0048 25 51 94 .. 514 555 .. 512 556 .. 0.92 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0031 WHD_TANC1 41 ealsweefkqrlelLsrllvkrsdgtlmffHpsfreWLlkrkgestkylcdare 94 +++++ +f qr++++ +l + g ++ ++ WL +++ ++++ +++re FUN_001106-T1 138 TKCHRIDFVQRFHSVPYVLATVRHGGITGPQDAMNMWLEEKQ--EDHFRICIRE 189 567889********************************8885..8888888875 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0048 WHD_TANC1 51 rlelLsrllvkrsdgtlmffHpsfreWLlkrkgestkylcdare 94 ++++L +lv+ + + ++++H + WL ++ +t + ++are FUN_001106-T1 514 KFQSLPTVLVSAEHERRSLLHDASSVWLEDVT--TTSFKICARE 555 68999************************996..9999999885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (681 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 845 (0.0330789); expected 510.9 (0.02) Passed bias filter: 671 (0.0262674); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.39u 0.37s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 6584.25 // Query: FUN_001107-T1 [L=398] Description: FUN_001107 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-87 293.3 0.0 1.5e-85 287.8 0.0 2.0 1 Actin Actin 0.0018 17.6 0.0 0.98 8.7 0.0 2.3 2 MreB_Mbl MreB/Mbl protein ------ inclusion threshold ------ 0.086 12.3 0.0 0.14 11.6 0.0 1.2 1 GATase_4 Glutamine amidotransferases class-II Domain annotation for each model (and alignments): >> Actin Actin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 287.8 0.0 1.7e-89 1.5e-85 6 409 .. 3 396 .. 1 397 [. 0.96 Alignments for each domain: == domain 1 score: 287.8 bits; conditional E-value: 1.7e-89 Actin 6 aiVlDvGssttraGyagedaPkavipsvvgkprgekveaklyvgde..alekrpglevrspvedGvvedwdavekiwehvlkee.lqvdpeehpll 98 ++VlD+G+s+ ++Gy ++P++ ip+++ k + e+ kl++gd+ ++++ +gl + p ++G++++wd ++iw++++ +e ++vd e+++l FUN_001107-T1 3 VLVLDNGASSAKVGYNTSENPRL-IPNCIFKAKSERR--KLFIGDQleECKDYSGLFYVTPFQKGFLVNWDIEKQIWDYIFGKEvMKVDFPETTVL 95 79*******************96.8****99999865..9******88888999999999**********************9999********** PP Actin 99 ltepalnpranrekaleimfEkfkvpalylaknavlsafasgka......talvvDsGasvtsvvpvldGyvLkkavrrsdlgGeaLteqlkells 188 +tep+ n ++ + + ei+fE+++++a++ ++ a lsa++s lvvD G+s t++vpv++G vLkk+v+r ++gG+ Lt++lke++s FUN_001107-T1 96 VTEPQFNFSSIKDAMEEILFEEYNFKAICRSTAAQLSAYKSHNDesekriMCLVVDTGYSFTHIVPVFNGKVLKKGVKRINVGGKLLTNHLKEIIS 191 ****************************************998888888899******************************************** PP Actin 189 sknievtPrylikkkkvvekeesaekeelekltesyktleeeevleeiKesvcevsedpekdeetss.....sspeksyelPDg............ 267 + +++ l+e++v++++Ke++c+vs+++++d + ++ + ++y+lPD FUN_001107-T1 192 YR--------------------------------QLHVLDETYVMNQVKEDTCYVSDNFFRDMQFAKlrgakNTVVRDYVLPDYthikrgyvksat 255 *7................................7899**********************977777777777999999****************** PP Actin 268 ...........stielgeerfrvpElLFnpsllgeeseleeekkkkllgiselivaainacdvdlrkeLlanivvtGGtsllpglteRlekelael 352 +++ +++erf vpElLF+ps++g ++ gi+e i++ain+ +++++++ + ni++tGG+sl+pg++eR+ +e+++l FUN_001107-T1 256 emllgskkeneQVLRMNNERFAVPELLFHPSDIGIQEM----------GIPEAISHAINELPTEMQPHCYMNILLTGGSSLFPGMKERVFSEVRRL 341 *********9999**********************877..........************************************************ PP Actin 353 apkgvkvkiiaaentverkysaWiGGSiLAslgtf.qqlwvskqeYeEqGasvverkc 409 ap +v v +++++ ++ aW GG+ L++++ f ++++v+k+eYe++G+++++ k+ FUN_001107-T1 342 APFDVDVAVHCPS---RPITHAWEGGAALSKTDVFlNKMCVTKAEYEDNGKNICREKF 396 ************9...9****************87589****************9997 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.0 0.00046 3.9 59 183 .. 57 185 .. 43 215 .. 0.72 2 ! 8.7 0.0 0.00012 0.98 253 298 .. 295 339 .. 290 373 .. 0.75 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.00046 MreB_Mbl 59 avrPlkdGviadlevaeellkyfikkvkkkkslskprvvicvPsgiteverrAvkeaakkaGare.vllieeplaAAiGaglp.veepsgnmvvdi 152 v+P+++G +++ ++ +++ y++ k +k +++++v+++ P+ + + A++e+ + + + + + A + + e+ +vvd FUN_001107-T1 57 YVTPFQKGFLVNWDIEKQIWDYIFGKEVMKVDFPETTVLVTEPQFNFSSIKDAMEEILFEEYNFKaICRSTAAQLSAYKSHNDeSEKRIMCLVVDT 152 689****************************************98888889999998765433330322223333333333330344445677788 PP MreB_Mbl 153 Gggttevavislggivts..ksvrvaGdeldea 183 G t + + g + ++ k++ v+G+ l ++ FUN_001107-T1 153 GYSFTHIVPVFNGKVLKKgvKRINVGGKLLTNH 185 877777777777776653336677777776654 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00012 MreB_Mbl 253 iveavkevLektppeLaadivdrgivltGGgallkgldkllseetg 298 i ea+++++++ p e+ + + i+ltGG++l+ g+++ + +e++ FUN_001107-T1 295 IPEAISHAINELPTEMQPHCYMN-ILLTGGSSLFPGMKERVFSEVR 339 77899999999999999998865.9************998877653 PP >> GATase_4 Glutamine amidotransferases class-II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 1.6e-05 0.14 155 201 .. 298 345 .. 289 351 .. 0.87 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.6e-05 GATase_4 155 ellralaelakeiaekGtfnfllsdGralfahasse.LvvilRkaPfg 201 ++++a++el +e+ + +n+ll+ G lf ++++ ++ ++R aPf+ FUN_001107-T1 298 AISHAINELPTEMQPHCYMNILLTGGSSLFPGMKERvFSEVRRLAPFD 345 677899************************9988663789*******6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (398 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 726 (0.0284204); expected 510.9 (0.02) Passed bias filter: 569 (0.0222744); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.42s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3895.56 // Query: FUN_001108-T1 [L=199] Description: FUN_001108 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-20 71.6 0.1 1.5e-19 70.9 0.1 1.3 1 AhpC-TSA_2 AhpC/TSA antioxidant enzyme Domain annotation for each model (and alignments): >> AhpC-TSA_2 AhpC/TSA antioxidant enzyme # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.9 0.1 5.9e-24 1.5e-19 1 114 [] 69 175 .. 69 175 .. 0.95 Alignments for each domain: == domain 1 score: 70.9 bits; conditional E-value: 5.9e-24 AhpC-TSA_2 1 rLsslkpeldaagvklvavgigtpgeleeFiketgfpfelyvDpsrklYkalglkrglkltlapgslqkglkeilkrakakgipgnkggeglqlGG 96 +Lssl+peld++gv+lv+v++++ g ++eF+ ++ + +ly+D+++k+Y + +++ + +g+l+ +++ + rak+kg++gn+ geg lGG FUN_001108-T1 69 ELSSLIPELDQKGVNLVGVVHEEKG-AKEFQ--PFLSSPLYLDEKKKFYGPEQRWM-----SISGFLRLSVWRSFFRAKGKGVKGNWLGEGRLLGG 156 699**********************.*****..******************99888.....568899999999999******************** PP AhpC-TSA_2 97 tfvfdkgg.evlyehrdee 114 +fv+++g+ ++l +h+++e FUN_001108-T1 157 VFVVGPGDqGILLDHKEKE 175 ******99*******9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (199 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 594 (0.0232531); expected 510.9 (0.02) Passed bias filter: 521 (0.0203954); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 2033.20 // Query: FUN_001109-T1 [L=590] Description: FUN_001109 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-22 77.8 61.0 2.7e-11 44.0 24.7 2.7 3 TCR Tesmin/TSO1-like CXC domain, cysteine-rich doma ------ inclusion threshold ------ 0.67 10.6 50.0 0.3 11.7 17.6 2.8 3 MSL2-CXC CXC domain of E3 ubiquitin-protein ligase MSL2 Domain annotation for each model (and alignments): >> TCR Tesmin/TSO1-like CXC domain, cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.0 24.7 2.1e-15 2.7e-11 2 37 .. 373 407 .. 372 408 .. 0.96 2 ! 43.2 23.9 3.8e-15 4.8e-11 2 36 .. 446 480 .. 445 482 .. 0.96 3 ? -2.3 0.1 0.66 8.5e+03 16 18 .. 546 548 .. 542 553 .. 0.58 Alignments for each domain: == domain 1 score: 44.0 bits; conditional E-value: 2.1e-15 TCR 2 kgCnCkkskClkkYCeCfaagkkCsseCkCeeCkNk 37 k+CnC+ks+Clk+YC+Cfa+g++C++ C+C +C+N+ FUN_001109-T1 373 KPCNCTKSQCLKLYCDCFANGEFCNN-CNCVNCSNN 407 89************************.********8 PP == domain 2 score: 43.2 bits; conditional E-value: 3.8e-15 TCR 2 kgCnCkkskClkkYCeCfaagkkCsseCkCeeCkN 36 kgC+Ck+s Clk+YCeC++a+ C++ CkC++CkN FUN_001109-T1 446 KGCHCKRSGCLKNYCECYEAKILCTNLCKCTGCKN 480 89********************************* PP == domain 3 score: -2.3 bits; conditional E-value: 0.66 TCR 16 CeC 18 C+C FUN_001109-T1 546 CQC 548 444 PP >> MSL2-CXC CXC domain of E3 ubiquitin-protein ligase MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 20.0 0.00035 4.5 18 48 .. 378 408 .. 369 414 .. 0.84 2 ? 11.7 17.6 2.4e-05 0.3 14 46 .. 447 480 .. 441 488 .. 0.86 3 ? -4.1 0.1 2 2.6e+04 27 30 .. 546 549 .. 543 555 .. 0.54 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00035 MSL2-CXC 18 pkttCrnnRCpCYksgnsCadCkCvgCkNPh 48 +k C C C+ +g+ C++C+Cv C N FUN_001109-T1 378 TKSQCLKLYCDCFANGEFCNNCNCVNCSNNM 408 577899999******************9965 PP == domain 2 score: 11.7 bits; conditional E-value: 2.4e-05 MSL2-CXC 14 gsskpkttCrnnRCpCYksgnsCad.CkCvgCkN 46 g + ++ C n C CY ++ C++ CkC+gCkN FUN_001109-T1 447 GCHCKRSGCLKNYCECYEAKILCTNlCKCTGCKN 480 55567889****************99******** PP == domain 3 score: -4.1 bits; conditional E-value: 2 MSL2-CXC 27 CpCY 30 C+C FUN_001109-T1 546 CQCL 549 4443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (590 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1374 (0.0537874); expected 510.9 (0.02) Passed bias filter: 417 (0.0163241); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.37s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5641.81 // Query: FUN_001109-T2 [L=468] Description: FUN_001109 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-12 45.5 24.7 2e-11 44.4 24.7 1.6 1 TCR Tesmin/TSO1-like CXC domain, cysteine-rich doma ------ inclusion threshold ------ 1.4 9.6 20.0 3.3 8.4 20.0 1.6 1 MSL2-CXC CXC domain of E3 ubiquitin-protein ligase MSL2 Domain annotation for each model (and alignments): >> TCR Tesmin/TSO1-like CXC domain, cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.4 24.7 1.6e-15 2e-11 2 37 .. 388 422 .. 387 423 .. 0.96 Alignments for each domain: == domain 1 score: 44.4 bits; conditional E-value: 1.6e-15 TCR 2 kgCnCkkskClkkYCeCfaagkkCsseCkCeeCkNk 37 k+CnC+ks+Clk+YC+Cfa+g++C++ C+C +C+N+ FUN_001109-T2 388 KPCNCTKSQCLKLYCDCFANGEFCNN-CNCVNCSNN 422 89************************.********8 PP >> MSL2-CXC CXC domain of E3 ubiquitin-protein ligase MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 20.0 0.00026 3.3 18 48 .. 393 423 .. 384 429 .. 0.83 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.00026 MSL2-CXC 18 pkttCrnnRCpCYksgnsCadCkCvgCkNPh 48 +k C C C+ +g+ C++C+Cv C N FUN_001109-T2 393 TKSQCLKLYCDCFANGEFCNNCNCVNCSNNM 423 577899999******************9965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (468 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1252 (0.0490115); expected 510.9 (0.02) Passed bias filter: 342 (0.0133881); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 4439.77 // Query: FUN_001110-T1 [L=600] Description: FUN_001110 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-52 177.3 11.8 5.5e-52 176.8 11.8 1.2 1 Ion_trans Ion transport protein 2.4e-24 86.0 0.1 5.6e-24 84.8 0.1 1.7 1 BTB_2 BTB/POZ domain 4.7e-15 55.7 4.6 4.7e-15 55.7 4.6 2.2 3 Ion_trans_2 Ion channel 0.00097 19.5 0.0 0.0069 16.8 0.0 2.2 2 BTB_3 BTB/POZ domain ------ inclusion threshold ------ 0.48 10.3 11.9 0.52 10.2 8.9 2.3 2 PKD_channel Polycystin cation channel Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.8 11.8 1.1e-55 5.5e-52 2 241 .. 228 475 .. 227 477 .. 0.93 Alignments for each domain: == domain 1 score: 176.8 bits; conditional E-value: 1.1e-55 Ion_trans 2 kifelfilllillntvvlaletyfqp..........................eekelklleildlvftviftlemllkiialglkkkYlrspwnil 71 ++++l+++ +i++++vvl++et ++ ++ + +++ l++vf+ +ft+e+l++++a + k+ ++rs+ n++ FUN_001110-T1 228 RVLALLSVSVIVASIVVLCIETLPEFtvlsndtipandtvkqqqikehnayaQSVK-SVFALLEIVFISWFTFEYLVRLFASPEKWLFVRSFLNVI 322 678899************************************99987766554444.*************************999*********** PP Ion_trans 72 Dfvvvlpslislilses...keslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekewe 164 D++++lp++++l+l ++ + sl+ lr+lrl+r++r+++l r++ gl++l+++l +sl++l+ l+++l++ ++if+++++ FUN_001110-T1 323 DLLAILPFYVELALRNTdsqNFSLAFLRILRLVRVFRIFKLSRHSSGLQILGHTLRKSLRELGLLIFFLAIGVVIFSSMVYYAE------------ 406 **************44455449********************************************************997776............ PP Ion_trans 165 npdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqelter 241 + +++t F+++++a++w+++t+tt+g+gd++++tl +k ++++++ l+gvl ++l+++vi++nf++++++ FUN_001110-T1 407 -NGVEETYFKSIPDAFWWALVTMTTVGYGDMYPQTLWGK-------LVGSCCALCGVLAIALPVPVIVSNFDTIYKK 475 .4467799*******************************.......****************************997 PP >> BTB_2 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.8 0.1 1.1e-27 5.6e-24 1 92 [. 98 187 .. 98 189 .. 0.96 Alignments for each domain: == domain 1 score: 84.8 bits; conditional E-value: 1.1e-27 BTB_2 1 vklnVgGtrfetskstLtrkpdtlLkklleteeldaydeetneyffDRspklFetiLnflrtggkLhepeevelkelleElefygleelale 92 + +nV+G r++t ++tL+r+p+tlL++ ++ + ++yde+++eyffDR+ ++Fe iL+f++++g+L +p e+ + lleE+ef++l e a++ FUN_001110-T1 98 IIINVSGFRYMTYAKTLERFPTTLLGNKVKRD--EFYDEDHDEYFFDRNIQVFELILYFYQSNGRLVCPPELAPEILLEEVEFFKLGEAAVN 187 689***************************55..*****************************************************99775 PP >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 1.4 7e+03 46 71 .. 221 248 .. 220 254 .. 0.57 2 ? -2.2 0.2 1.1 5.6e+03 63 71 .. 291 299 .. 280 319 .. 0.52 3 ! 55.7 4.6 9.2e-19 4.7e-15 3 74 .. 393 466 .. 386 470 .. 0.81 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.4 Ion_trans_2 46 Pr.tdagrlft.ivyiliGiplfllfla 71 P ++a r+++ + +i ++++l++ FUN_001110-T1 221 PDsSKAARVLAlLSVSVIVASIVVLCIE 248 5556666666655555555555555555 PP == domain 2 score: -2.2 bits; conditional E-value: 1.1 Ion_trans_2 63 iplfllfla 71 i+++++f+ FUN_001110-T1 291 IVFISWFTF 299 444444432 PP == domain 3 score: 55.7 bits; conditional E-value: 9.2e-19 Ion_trans_2 3 lllvlifgtviyll...eegwegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllflavlg 74 + +v+++++v+y+ ee++ s+ da+++++vt+tTvGYGd++P+t +g+l+ + +l G++ ++l + v++ FUN_001110-T1 393 IGVVIFSSMVYYAEngvEETY-FKSIPDAFWWALVTMTTVGYGDMYPQTLWGKLVGSCCALCGVLAIALPVPVIV 466 345556666666669974443.57*****************************************9998877665 PP >> BTB_3 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 1.3e-06 0.0069 2 89 .. 98 180 .. 97 190 .. 0.86 2 ? -1.0 0.0 0.45 2.3e+03 20 35 .. 436 451 .. 432 455 .. 0.89 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.3e-06 BTB_3 2 ltlvvdetrfvvdkslftahPdtmlgrmfssslernltkpnekGeyevaegissevfraildyyk.tGvikcPpsvsikelreacdyll 89 + + v + r++ + ++++P t+lg +++r+ +++ ey +++i +vf+ il +y+ +G++ cPp + + l e +++ FUN_001110-T1 98 IIINVSGFRYMTYAKTLERFPTTLLGN----KVKRDEFYDEDHDEYFFDRNI--QVFELILYFYQsNGRLVCPPELAPEILLEEVEFFK 180 56778999****************986....5677888899*********99..79********846*******998888888888775 PP == domain 2 score: -1.0 bits; conditional E-value: 0.45 BTB_3 20 ahPdtmlgrmfsssle 35 +P+t+ g++ +s+++ FUN_001110-T1 436 MYPQTLWGKLVGSCCA 451 79***********985 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 1.7 0.36 1.9e+03 43 116 .. 229 304 .. 220 308 .. 0.60 2 ? 10.2 8.9 0.0001 0.52 37 191 .. 279 439 .. 268 472 .. 0.62 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.36 PKD_channel 43 vwnlldlaivvlsvvlivlailrevlakkllkkveaeketfldFdevaqldqllriilavl..vflttlkllkvlr 116 v ll + ++v s+v++ + l e+++ + + ++ ++ ++ +e +q+++ + a+l vf+++ + +++r FUN_001110-T1 229 VLALLSVSVIVASIVVLCIETLPEFTVLSNDTIPANDTVKQQQIKEHNAYAQSVKSVFALLeiVFISWFTFEYLVR 304 6667777777777777777777777666665555556666666666666666666666653335666655555555 PP == domain 2 score: 10.2 bits; conditional E-value: 0.0001 PKD_channel 37 asylrsvwnlldlaivvlsvvlivlailrevlakkllkkve..aeketfldFdevaql..dqllriilavlvflttlkllkv...lrfnktmsllt 125 a+ ++sv+ ll+++ + +++ +++++ + + +++++ + + l+F l + + +la+l +l +++++++ +r ++ ++ l+ FUN_001110-T1 279 AQSVKSVFALLEIVFISWFTFEYLVRLFASPEKWLFVRSFLnvIDLLAILPFYVELALrnTDSQNFSLAFLRILRLVRVFRIfklSRHSSGLQILG 374 4556666777776666666666666666665555555555532344556666544333004456778999999998887665000555667999** PP PKD_channel 126 ktlaralkdlagfalvivilflayaqlgv.llfGtqasnfsnlvksiltlfrlilgdfqytelesgn 191 +tl ++l++l + + ++i ++ + +++ +G ++ f+ + ++ + ++ ++y ++ + + FUN_001110-T1 375 HTLRKSLRELGLLIFFLAIGVVIFSSMVYyAENGVEETYFKSIPDAFWWALV-TMTTVGYGDM-YPQ 439 *********9888888777777777766515699999999999999988744.4455666666.444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (600 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1119 (0.043805); expected 510.9 (0.02) Passed bias filter: 658 (0.0257585); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.36u 0.40s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5743.37 // Query: FUN_001111-T1 [L=594] Description: FUN_001111 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-19 70.3 0.8 2.8e-13 50.5 0.0 3.4 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 3.5e-13 50.0 1.0 2e-07 31.1 0.0 3.9 5 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 8.2e-13 48.5 0.4 3.6e-08 33.3 0.0 3.2 4 WD40_Prp19 Prp19 WD40 domain 1.2e-12 48.1 0.2 4.9e-07 29.7 0.0 3.3 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 1.6e-12 48.0 0.8 2.6e-09 37.5 0.0 3.8 5 Beta-prop_EML Echinoderm microtubule-associated 3.6e-12 46.4 3.0 5e-09 36.0 0.2 4.1 4 Beta-prop_THOC3 THOC3 beta-propeller domain 5.7e-11 42.6 0.0 6.2e-07 29.3 0.0 3.2 3 EIF3I EIF3I 9.8e-11 42.2 9.3 8.5e-06 26.6 0.0 5.3 3 WD40 WD domain, G-beta repeat 1.7e-10 41.1 2.1 0.00021 21.1 0.0 3.9 4 WD40_WDHD1_1st WDHD1 first WD40 domain 2.5e-10 40.6 4.5 4.4e-09 36.5 0.2 3.3 3 Beta-prop_WDR5 WDR5 beta-propeller domain 1.6e-08 34.8 0.4 0.00021 21.3 0.1 2.7 3 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 7.8e-08 32.4 2.6 8e-05 22.5 0.1 3.5 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 2e-07 30.9 0.2 1.8e-06 27.7 0.0 2.5 3 WDR55 WDR55 2.2e-07 30.8 0.1 9.9e-06 25.4 0.0 2.5 2 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 7.1e-07 29.2 2.7 0.013 15.2 0.1 3.7 4 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 1.4e-06 28.4 1.6 0.0016 18.4 0.1 4.2 3 Beta-prop_EML_2 Echinoderm microtubule-associated 5.1e-06 26.2 0.2 0.11 11.9 0.0 2.9 3 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 3.8e-05 23.2 0.0 0.0019 17.6 0.0 2.4 2 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 4.2e-05 23.6 0.9 0.0025 17.8 0.1 2.8 3 Beta-prop_EIPR1 EIPR1 beta-propeller 0.00043 20.2 0.1 0.0018 18.1 0.0 2.1 2 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 0.00082 18.7 0.5 0.0072 15.6 0.0 2.5 3 Beta-prop_WDR41 WDR41 0.00097 19.1 2.9 4.4 7.1 0.0 4.8 5 Beta-prop_RIG_2nd RIG second beta-propeller 0.0025 17.3 1.0 1.2 8.5 0.0 3.6 4 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 0.0035 17.8 3.1 0.032 14.7 0.1 3.6 2 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 0.0036 17.0 0.0 0.017 14.7 0.1 2.0 2 WDR54 WDR54 0.0044 16.4 0.8 0.035 13.4 0.0 2.1 2 Beta-prop_SCAP SCAP Beta-propeller ------ inclusion threshold ------ 0.014 14.8 0.2 0.087 12.2 0.0 2.2 3 Beta-prop_IP5PC_F IP5P C-F beta-propeller 0.015 14.7 0.4 0.048 13.1 0.1 1.9 2 WD40_Gbeta G protein beta WD-40 repeat protei 0.072 13.8 0.2 19 6.1 0.0 3.7 3 ANAPC4_WD40 Anaphase-promoting complex subunit 0.095 12.5 1.6 0.44 10.3 0.1 2.7 3 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 Domain annotation for each model (and alignments): >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.42 3.5e+02 8 172 .. 74 158 .. 65 167 .. 0.40 2 ! 50.5 0.0 3.3e-16 2.8e-13 12 160 .. 214 362 .. 203 384 .. 0.80 3 ! 14.9 0.0 2.6e-05 0.022 85 146 .. 475 547 .. 469 586 .. 0.74 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.42 Beta-prop_WDR3_1st 8 lekvlvWdlkkgekvatl....egeksevtala..aspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskD 92 ++++vW+ + +k + ++ +++ + l+ + +++ + + +d s r+++++ + ++ ++ ++++ +la+++ FUN_001111-T1 74 KNEINVWNFSEDKKPGKSanafQTITTDLKFLHilFIRRRWLYVTHCSDLSMRIFSAKFHPMS--ITEMTRTILSLAYNE----------- 151 455555555444433322111122222222222002233333344445555555554444322..223334444444444........... PP Beta-prop_WDR3_1st 93 tdiivwDvvaeaglfrLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvt 172 ++ ++t FUN_001111-T1 152 -------------------------------------------------------------------------IRDEIIT 158 .........................................................................4444444 PP == domain 2 score: 50.5 bits; conditional E-value: 3.3e-16 Beta-prop_WDR3_1st 12 lvWdlkkgekvatlege.ksevtalaaspdgkklavGyadgsirlwdlesge..levtfngHksavtalafdkdgsrLasGskDtdiivwD 99 ++ d+ + ++ + ++++ + + t+ + + + + +G ++gsir w+++ ++ + ++f gH++++t l ++++s L+s+s D++i +w+ FUN_001111-T1 214 AMIDVASYKERRFFQKKcEFSFTCCVFFSPASYFITGDKNGSIRAWSTSLNSfpMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWN 304 555666666666665431567788777777889*************997666226789********************************* PP Beta-prop_WDR3_1st 100 vvaeaglfrLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevws 160 +++++frL+ ++ v + +l++ ++l S + +k+W l+ h + t+ + r + w+ FUN_001111-T1 305 FDTGTQTFRLETGEEIVE-MGLLSS-DLLYYHS-HHHLKIWSLNLFHSLFTILSSRIRRWA 362 ***********9877666.666655.3555555.5789***********999998877665 PP == domain 3 score: 14.9 bits; conditional E-value: 2.6e-05 Beta-prop_WDR3_1st 85 rLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvafle...........ekkvlvssSkDtliklWdletqh 146 L+ G + +i ++D + + H++qvt+++++ + + l+s + D ++++W l ++ FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSAsvstesadsigSVDRLISYGTDCVVRIWKLVHKE 547 6788899999999999999999999************97444433333333458**************97665 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.22 1.8e+02 234 257 .. 63 87 .. 40 128 .. 0.69 2 ? 2.1 0.0 0.16 1.3e+02 155 240 .. 73 160 .. 70 183 .. 0.61 3 ! 31.1 0.0 2.3e-10 2e-07 51 172 .. 190 313 .. 153 322 .. 0.80 4 ! 12.5 0.0 0.00011 0.095 200 266 .. 296 358 .. 294 384 .. 0.80 5 ! 11.9 0.0 0.00017 0.14 101 181 .. 471 560 .. 391 565 .. 0.82 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.22 WD40_CDC20-Fz 234 kelvsthgysk.nqivlwkypslkk 257 + +vs hg k n+i++w++++ kk FUN_001111-T1 63 HSFVSHHGVGKkNEINVWNFSEDKK 87 6789999986438999999876555 PP == domain 2 score: 2.1 bits; conditional E-value: 0.16 WD40_CDC20-Fz 155 ndntvkiwdlrsls.p...llkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgsqvtsllwskeekelvsth 240 ++n +++w++++ + p + ++ + k l ++ L +D ++r+++++ ++++ +++ + sl++++ ++e++++ FUN_001111-T1 73 KKNEINVWNFSEDKkPgksANAFQTITTDLKFLHILFIRRRWLYVTH-CSDLSMRIFSAK-FHPMSITEMTRTILSLAYNEIRDEIITGI 160 56666666665432131114445555555666666666666666544.456666666655.55666666777777777777777777664 PP == domain 3 score: 31.1 bits; conditional E-value: 2.3e-10 WD40_CDC20-Fz 51 sdyvtsvkwsed.gelLavGtssgevelwdvekkkklrtleghss..rvgalaw.nenllssGsrdgkilhhDvrtkelevvktlkahkqevcglk 142 d v s++ +++ +++La+++ ++ ++dv + k+ r ++++ + +++ + + +++G+++g+i+ + + +++ +v+++ +h+ +++ l FUN_001111-T1 190 LDWVISLSVDDAsKQILAIAD--VRIAMIDVASYKERRFFQKKCEfsFTCCVFFsPASYFITGDKNGSIRAWSTSLNSFPMVTQFLGHTARITKLL 283 467888888865146777765..68**********999999876421444444424567************************************* PP WD40_CDC20-Fz 143 wspdgrllAsGgndntvkiwdlrslspllk 172 + ++++ll s++ d+t+++w++++ +++++ FUN_001111-T1 284 VHSEESLLISSSLDKTIRLWNFDTGTQTFR 313 *********************987665554 PP == domain 4 score: 12.5 bits; conditional E-value: 0.00011 WD40_CDC20-Fz 200 aDktirlwntntgkllksvdtgsqvtsllwskeekelvsthgysknqivlwkypslkkvaeleghte 266 Dktirlwn tg+++ +++tg ++ ++ + ++l+ h s++++++w+ + ++ + ++ + + FUN_001111-T1 296 LDKTIRLWNFDTGTQTFRLETGEEIVEMGLLS--SDLLYYH--SHHHLKIWSLNLFHSLFTILSSRI 358 6**************************99877..6888888..567899999988888777655554 PP == domain 5 score: 11.9 bits; conditional E-value: 0.00017 WD40_CDC20-Fz 101 wnenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgr...........llAsGgndntvkiwdlrslspllkltehkaavk 181 ++ ll++G+ +g+i D + + + +++ah+++v++lk+s++ + l s g d +v+iw+l + + + a vk FUN_001111-T1 471 LKSGLLFAGHYNGQISLVDGKDVYM--KGNVQAHQGQVTNLKVSASVStesadsigsvdRLISYGTDCVVRIWKLVHKEYGCVSIQQLARVK 560 466789*************999865..579**************9653334444555559999999*******9887776555555666666 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 4.1 3.5e+03 89 89 .. 97 97 .. 69 147 .. 0.53 2 ! 33.3 0.0 4.2e-11 3.6e-08 27 131 .. 209 316 .. 193 328 .. 0.76 3 ? 4.5 0.0 0.026 22 147 186 .. 474 512 .. 359 513 .. 0.70 4 ! 11.3 0.1 0.00022 0.19 19 83 .. 473 548 .. 445 564 .. 0.78 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 4.1 WD40_Prp19 89 k 89 + FUN_001111-T1 97 T 97 1 PP == domain 2 score: 33.3 bits; conditional E-value: 4.2e-11 WD40_Prp19 27 aDknvvlfdresekvlatlkgh.tkkvtavafhpsedvlvsasaDktvrvwkkeeket..aatlkkhkaevtslsvhptgdylvsaskDgtwalhd 119 aD ++++ d +s k + +++ + t+++f + ++ ++++ + +++r w+++ +++ ++ + h+a++t+l vh +++l+s+s D+t+ l++ FUN_001111-T1 209 ADVRIAMIDVASYKERRFFQKKcEFSFTCCVFFSPASYFITGDKNGSIRAWSTSLNSFpmVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWN 304 567777777777777776665425578899999999999999999999999998776511556778999999999999999999999999999999 PP WD40_Prp19 120 letgktllkvkd 131 ++tg++ +++ FUN_001111-T1 305 FDTGTQTFRLET 316 999998877655 PP == domain 3 score: 4.5 bits; conditional E-value: 0.026 WD40_Prp19 147 GlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFS 186 Gll+ +G +g++++ D k+ + ++++h+g+vt+l++S FUN_001111-T1 474 GLLF-AGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVS 512 5555.7999999***********************99998 PP == domain 4 score: 11.3 bits; conditional E-value: 0.00022 WD40_Prp19 19 knlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedv...........lvsasaDktvrvwkkeeket 83 + l+++G +++ l d ++ + ++++h+ +vt+++++ s ++ l+s ++D vr+wk +ke FUN_001111-T1 473 SGLLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVSTesadsigsvdrLISYGTDCVVRIWKLVHKEY 548 557888889999*************************9986543222334455555*************9866653 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.0 5.8e-10 4.9e-07 223 287 .. 238 304 .. 193 311 .. 0.74 2 ? 0.3 0.0 0.54 4.6e+02 12 67 .. 329 387 .. 319 436 .. 0.61 3 ! 13.5 0.0 5.2e-05 0.044 53 146 .. 476 584 .. 449 589 .. 0.78 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 5.8e-10 Beta-prop_WDR3_2nd 223 vafvpktHylfsagkdkkvkyWDa..dkfekiqtleghagevwalavsskgkfvvsashDksiRlwe 287 f + + y+++ +k+++++ W + ++f +++++ gh++ +++l v s+ ++++s+s Dk+iRlw+ FUN_001111-T1 238 CVFFSPASYFITGDKNGSIRAWSTslNSFPMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWN 304 4555666788888888888888763357888888888888888888888888888888888888885 PP == domain 2 score: 0.3 bits; conditional E-value: 0.54 Beta-prop_WDR3_2nd 12 klllsassesvkiwnvkslecirtieseyal..clafvpgd.rhvlvgtkdGklevldl 67 +ll s++++kiw+ + +++ ti s++ + + pg + vl+ ++dG +++l+ FUN_001111-T1 329 DLLYYHSHHHLKIWSLNLFHSLFTILSSRIRrwARVKSPGYpARVLLHSEDGGVRLLSP 387 45667788889999998888888887654430034444553135666666666666554 PP == domain 3 score: 13.5 bits; conditional E-value: 5.2e-05 Beta-prop_WDR3_2nd 53 vlvgtkdGklevldlasaelletieahegavwsvaltpde...........kglvtggaDkkvkfwefelveee...eskakkls.lkhtr 128 + +g +G+++++d + + +++ah+g+v +++++ + +l++ g+D v++w++ e ++ +++ l++ r FUN_001111-T1 476 LFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVstesadsigsvDRLISYGTDCVVRIWKLVHKEYGcvsIQQLARVKlLQAPR 566 567999*************************998887633333344566667899************99876543223333444415788* PP Beta-prop_WDR3_2nd 129 tlklsddvlcvkvspdkk 146 l ++ + lc+ +++++ FUN_001111-T1 567 DLAMAGNTLCMAMADNNV 584 ***********9998875 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 6.8 5.8e+03 88 101 .. 74 87 .. 58 103 .. 0.62 2 ? -1.0 0.0 1.6 1.4e+03 154 182 .. 139 167 .. 121 171 .. 0.74 3 ! 37.5 0.0 3e-12 2.6e-09 144 229 .. 221 307 .. 212 327 .. 0.84 4 ? -2.0 0.0 3.4 2.9e+03 196 255 .. 336 393 .. 329 407 .. 0.60 5 ? 5.7 0.1 0.014 12 167 211 .. 473 516 .. 471 562 .. 0.81 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 6.8 Beta-prop_EML 88 ehvlsvWdwqkgek 101 ++ + vW++++++k FUN_001111-T1 74 KNEINVWNFSEDKK 87 34455555555544 PP == domain 2 score: -1.0 bits; conditional E-value: 1.6 Beta-prop_EML 154 ekpkyvlclafsengd.vitGdsnGnilvW 182 e +++l+la++e d +itG G i++W FUN_001111-T1 139 EMTRTILSLAYNEIRDeIITG-IAGGIMTW 167 567889999999876636666.55667777 PP == domain 3 score: 37.5 bits; conditional E-value: 3e-12 Beta-prop_EML 144 ekkkgifeksekpkyvlclafsengdvitGdsnGnilvWskgtnkiskavk.kahegsvfsllvlkdgtllsgggkdgkivawdanl 229 +k++ +f+k+ + ++ +c+ fs+ +itGd+nG+i Ws++ n+ ++ h+ ++ llv ++++ll ++ d++i w+ + FUN_001111-T1 221 YKERRFFQKKCEFSFTCCVFFSPASYFITGDKNGSIRAWSTSLNSFPMVTQfLGHTARITKLLVHSEESLLISSSLDKTIRLWNFDT 307 578899**********************************99997654443258***************999999999999998553 PP == domain 4 score: -2.0 bits; conditional E-value: 3.4 Beta-prop_EML 196 ahegsvfsllvlkdgtllsgggkdgkivawda..nleklketelpesaggvraivegkgdql 255 h+ +++sl + ++ + + + +i w + + +++ l ++ ggvr +++ +g++l FUN_001111-T1 336 HHHLKIWSLNLFHSLFTILS----SRIRRWARvkSPGYPARVLLHSEDGGVRLLSPVHGSEL 393 56666777766666555444....34444443102233466777788888888887777644 PP == domain 5 score: 5.7 bits; conditional E-value: 0.014 Beta-prop_EML 167 ngdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgt 211 +g +++G nG+i + + ++ ++ +v+ ah+g+v+ l+v+ + + FUN_001111-T1 473 SGLLFAGHYNGQISLVDGKDVYMKGNVQ-AHQGQVTNLKVSASVS 516 78899**********9977777777776.*********9987644 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 2.1 1.8e+03 24 77 .. 75 131 .. 69 159 .. 0.54 2 ! 36.0 0.2 5.9e-12 5e-09 110 222 .. 211 327 .. 191 358 .. 0.67 3 ? -1.9 0.0 2.2 1.9e+03 21 61 .. 377 418 .. 371 441 .. 0.46 4 ! 6.3 0.1 0.007 6 143 199 .. 475 542 .. 470 588 .. 0.57 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 2.1 Beta-prop_THOC3 24 ktvrvwnlekskl.ske.telkghtdsVeqlawspthpd.llatassDktvrlWdvr 77 + ++vwn+ ++k+ k+ + ++ t + + l + ++ l++t +sD ++r++ ++ FUN_001111-T1 75 NEINVWNFSEDKKpGKSaNAFQTITTDLKFLHILFIRRRwLYVTHCSDLSMRIFSAK 131 456666666554322221345555555555554433333145666666666666665 PP == domain 2 score: 36.0 bits; conditional E-value: 5.9e-12 Beta-prop_THOC3 110 dtvslidvrtgkvkkeekfkke..vnevafspdgkllllttgdgtvevlsy..psleevktlkahtsnclcvafdpkgrylAvGsaDalvslWD 199 + +idv + k ++ + k e ++ + f + ++++++ ++g+++ +s+ +s+ v+++ +ht+ ++ + ++ ++ +l ++s D++++lW+ FUN_001111-T1 211 VRIAMIDVASYKERRFFQKKCEfsFTCCVFFSPASYFITGDKNGSIRAWSTslNSFPMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWN 304 4677777777777776555544114455555556777777778888877653367777777788888888888888888888888888888888 PP Beta-prop_THOC3 200 leeliclrtltrlespvrsvsFS 222 +++++ + l+ e+ v+ S FUN_001111-T1 305 FDTGTQTFRLETGEEIVEMGLLS 327 77777776666666666555555 PP == domain 3 score: -1.9 bits; conditional E-value: 2.2 Beta-prop_THOC3 21 saDktvrvwnleksklske.telkghtdsVeqlawspthpdl 61 s+D vr+ ++ ++++ ++ ++ + ++ +a +p ++++ FUN_001111-T1 377 SEDGGVRLLSPVHGSELTAvLPITTMSADIVDVAHNPRQEKI 418 344444444444443333212344444444444444444433 PP == domain 4 score: 6.3 bits; conditional E-value: 0.007 Beta-prop_THOC3 143 llllttgdgtvevlsypsleevktlkahtsnclcvafdpkgr...........ylAvGsaDalvslWD 199 ll++++ +g++ +++ +++ +++ah+++++ ++++ + l + + D +v++W FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVStesadsigsvdRLISYGTDCVVRIWK 542 67777777777777777777777777777777777776542211111111111333333444444444 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.32 2.7e+02 96 177 .. 51 132 .. 38 163 .. 0.68 2 ! 29.3 0.0 7.3e-10 6.2e-07 96 222 .. 182 310 .. 141 329 .. 0.81 3 ! 8.5 0.0 0.0016 1.4 160 200 .. 475 515 .. 400 544 .. 0.88 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.32 EIF3I 96 vrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghedgeiskydlkt 177 r v +g+ +v ++ +gkk ei+v + +++++ ++ +++++ +++ k+ +l+ +t +d ++ +++k FUN_001111-T1 51 LRVVLHVNTGSGHSFVSHHGVGKKNEINVWNFSEDKKPGKSANAFQTITTDLKFLHILFIRRRWLYVTHCSDLSMRIFSAKF 132 5556666667777778888888888888888888888888888888888888888777777776666666666666666554 PP == domain 2 score: 29.3 bits; conditional E-value: 7.3e-10 EIF3I 96 vrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktiitghedgeiskydlktge..klksvkehek 189 +++f++ + + l++d++ ++ +i + i + ++ +e+ + ++ e ++t++++ + ++ itg ++g+i ++++ ++ ++++ h++ FUN_001111-T1 182 LVNCSFTPLDWVISLSVDDASKQILAIADVRIAMIDVASYKERRFFQKKCEFSFTCCVFFSPASYFITGDKNGSIRAWSTSLNSfpMVTQFLGHTA 277 457888888999999999998888887777777777666677777777777899999999999***************987766226788889*** PP EIF3I 190 qitdlqlskdktylitaskDktaklldvetlev 222 +it l +++++++li++s Dkt +l++ +t ++ FUN_001111-T1 278 RITKLLVHSEESLLISSSLDKTIRLWNFDTGTQ 310 *************************99987655 PP == domain 3 score: 8.5 bits; conditional E-value: 0.0016 EIF3I 160 tiitghedgeiskydlktgeklksvkehekqitdlqlskdk 200 + +gh +g+is +d k+ + +v++h+ q+t+l++s+ FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASV 515 6789********************************99765 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.1 0.0007 0.6 15 39 .] 236 260 .. 227 260 .. 0.79 2 ! 26.6 0.0 1e-08 8.5e-06 4 39 .] 269 304 .. 266 304 .. 0.92 3 ? 5.9 0.5 0.036 31 25 38 .. 517 541 .. 495 542 .. 0.64 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0007 WD40 15 tsla.fspdgsllasgsdDgtvklWd 39 t++ fsp + ++ +g+++g+++ W+ FUN_001111-T1 236 TCCVfFSPASYFI-TGDKNGSIRAWS 260 5666377777776.9**********6 PP == domain 2 score: 26.6 bits; conditional E-value: 1e-08 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++ + gHt+ +t l ++ sll+s+s D+t++lW+ FUN_001111-T1 269 VTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWN 304 56688**999*************************7 PP == domain 3 score: 5.9 bits; conditional E-value: 0.036 WD40 25 l...........lasgsdDgtvklW 38 l+s + D+ v++W FUN_001111-T1 517 TesadsigsvdrLISYGTDCVVRIW 541 444444444444999999******* PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.1 0.00022 0.19 103 252 .. 118 262 .. 72 268 .. 0.80 2 ! 21.1 0.0 2.4e-07 0.00021 121 165 .. 269 313 .. 263 328 .. 0.88 3 ? 5.0 0.1 0.02 17 100 161 .. 475 547 .. 414 560 .. 0.78 4 ? 2.8 0.0 0.089 76 19 36 .. 528 545 .. 520 587 .. 0.63 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00022 WD40_WDHD1_1st 103 agseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlpksndfsaskslcrlawepksgkllavP 197 +D + ++ s + + +++++ + +ls+a++ + +++ ++ G + W + ++ + ++f+ + + l+ + s+++la++ FUN_001111-T1 118 THCSDLSMRIFSA-K-FHPMSITEMTRTILSLAYNEIRDEIIT-GIAGGIMTWRFPIGQMDPLIPGQLVNCSFTPLDWVISLSVDDASKQILAIA 209 5567778888774.3.346789999999999999998888775.667888899999999999998888899999999999999999999999997 PP WD40_WDHD1_1st 198 vekevklyerdtweeafklsknklsedisivafSpcGkylaaatvdgeilvWdva 252 + ++ +++ +++e+ ++k+ + ++v fSp +y +++++g+i W+++ FUN_001111-T1 210 -DVRIAMIDVASYKERRFFQKKCEFSFTCCVFFSPA-SYFITGDKNGSIRAWSTS 262 .5689*********9988888777766666666775.78889**********986 PP == domain 2 score: 21.1 bits; conditional E-value: 2.4e-07 WD40_WDHD1_1st 121 qktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvkt 165 ++++ gh+a ++ + +++++ +l+Sss D t+++W++++++++ FUN_001111-T1 269 VTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWNFDTGTQTFR 313 57899*********************************9987654 PP == domain 3 score: 5.0 bits; conditional E-value: 0.02 WD40_WDHD1_1st 100 llaagseDftikvvsvedsskqktleghkapvlsvaldpkg...........eylaSsscDGtvkiWdieske 161 ll ag + +i +v+ +d + +++ h+++v+ ++++++ l+S ++D v+iW++ ke FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVstesadsigsvDRLISYGTDCVVRIWKLVHKE 547 6778888888888888888888888888888887777665433344455555568888888888888887665 PP == domain 4 score: 2.8 bits; conditional E-value: 0.089 WD40_WDHD1_1st 19 kliTcGsDgdvriwegle 36 +li+ G+D vriw+ + FUN_001111-T1 528 RLISYGTDCVVRIWKLVH 545 567777777777776443 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.96 8.2e+02 62 108 .. 115 159 .. 52 180 .. 0.66 2 ! 36.5 0.2 5.2e-12 4.4e-09 69 171 .. 210 315 .. 193 393 .. 0.69 3 ? 3.7 0.2 0.05 42 103 161 .. 474 543 .. 470 555 .. 0.67 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.96 Beta-prop_WDR5 62 llasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgnllvSG 108 l ++ D ++ri++++ + + +++ t ++++a+n + +++G FUN_001111-T1 115 LYVTHCSDLSMRIFSAKFHPM--SITEMTRTILSLAYNEIRDEIITG 159 334444567788888877666..677778888888888888888877 PP == domain 2 score: 36.5 bits; conditional E-value: 5.2e-12 Beta-prop_WDR5 69 DktvriwdvetgkllktlkgHtnyvf.cvaFnpkgnllvSGsfDetvrlWdvrtgk..clktlpaHsdpvsavdfnrdgtlivsssyDgliriwd 160 D + + dv++ k + ++ ++ f c+ F + ++G + ++r W ++ ++ ++ + +H+ ++ + +++ +l++sss+D +ir+w+ FUN_001111-T1 210 DVRIAMIDVASYKERRFFQKKCEFSFtCCVFFSPASYFITGDKNGSIRAWSTSLNSfpMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWN 304 55666667777776666666555433255555556667778888888888765544225677778888888888888888888888888888888 PP Beta-prop_WDR5 161 tetgqclktlv 171 +tg+ + l FUN_001111-T1 305 FDTGTQTFRLE 315 88777665553 PP == domain 3 score: 3.7 bits; conditional E-value: 0.05 Beta-prop_WDR5 103 nllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgt...........livsssyDgliriwdt 161 ll +G ++ ++ l d + + ++aH+ +v+ ++ + + ++s +D+++riw FUN_001111-T1 474 GLLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVStesadsigsvdRLISYGTDCVVRIWKL 543 5777788888888888888888888888888887766665443233333344445777788888888865 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 4.3 3.6e+03 216 239 .. 76 99 .. 70 128 .. 0.55 2 ! 21.3 0.1 2.5e-07 0.00021 168 266 .] 207 306 .. 194 306 .. 0.83 3 ! 10.8 0.0 0.00039 0.33 63 244 .. 315 511 .. 308 543 .. 0.80 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 4.3 Beta-prop_WDR36-Utp21_1st 216 dialwdLekrrlvhvlrnaHeggv 239 +i +w+ ++ + + na ++ FUN_001111-T1 76 EINVWNFSEDKKPGKSANAFQTIT 99 556666666655555555555533 PP == domain 2 score: 21.3 bits; conditional E-value: 2.5e-07 Beta-prop_WDR36-Utp21_1st 168 glasGeivlhnikkdetllklkqe.egpvtsisFrtDgepvlatgsssGdialwd..LekrrlvhvlrnaHeggvtkleflpgq 248 ++a+ +i ++++ ++ ++++ e + t+ F + +++++tg ++G+i w L++ +v++ H++++tkl + +++ FUN_001111-T1 207 AIADVRIAMIDVASYKERRFFQKKcEFSFTCCVFFSP-ASYFITGDKNGSIRAWStsLNSFPMVTQF-LGHTARITKLLVHSEE 288 4567788888888877777777774568999999986.6799************7336666666666.369************* PP Beta-prop_WDR36-Utp21_1st 249 pllvtsgaDNslkewifD 266 ll++s+ D +++ w fD FUN_001111-T1 289 SLLISSSLDKTIRLWNFD 306 *****************9 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00039 Beta-prop_WDR36-Utp21_1st 63 eheekikkllvfgdhlvavdednsllvwkieteelyteiefseeefeitallhpsTYlnKilvgskqGslqlwNirtgkliytf 146 e+ e+i ++ ++ + l+ + ++++l++w+++ + +i s + + a ++ + Y ++l+ s++G ++l+ +g+ + + FUN_001111-T1 315 ETGEEIVEMGLLSSDLLYYHSHHHLKIWSLNLFHSLFTILSS--RIRRWARVKSPGYPARVLLHSEDGGVRLLSPVHGSELTAV 396 56789999999999****************998888887776..48888899999*****************998888777777 PP Beta-prop_WDR36-Utp21_1st 147 ...ksfksaitaleqspaldvvaiglasGeivlhnikkd....etllklkqeegpvtsisFrtDg...........epvlatgs 212 +++++ i +++ p + + + l++ +++++ +++ ++l ++ ++ v+s++ + + + +l +g+ FUN_001111-T1 397 lpiTTMSADIVDVAHNPRQEKIYLVLSTRAVLVFESNTNpccaHQLWVAESPDEGVCSLAMINAEfalekgeiplkSGLLFAGH 480 33356779*************************9998872111444444556788999999888555555666666899***** PP Beta-prop_WDR36-Utp21_1st 213 ssGdialwdLekrrlvhvlrnaHeggvtklef 244 +G+i l d ++ + + + +aH+g+vt+l++ FUN_001111-T1 481 YNGQISLVDGKDVYMKGNV-QAHQGQVTNLKV 511 *******998888887777.799998887765 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.038 32 200 269 .. 193 261 .. 138 269 .. 0.72 2 ! 22.5 0.1 9.4e-08 8e-05 232 274 .. 268 310 .. 262 342 .. 0.84 3 ? 4.0 0.0 0.04 34 170 191 .. 527 548 .. 473 586 .. 0.63 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.038 Beta-prop_WDR36-Utp21_2nd 200 sisklvlhressllavalddfsilvvDidtrrvvRkfsgh.knritDltfspdarWlitasmDstirtwdl 269 is +v + ++la+ d+ i ++D+ + + R f+ + + t +f a ++it +ir w+ FUN_001111-T1 193 VISLSVDDASKQILAI--ADVRIAMIDVASYKERRFFQKKcEFSFTCCVFFSPASYFITGDKNGSIRAWST 261 4555555556666666..59**********999887776513456777787888999************86 PP == domain 2 score: 22.5 bits; conditional E-value: 9.4e-08 Beta-prop_WDR36-Utp21_2nd 232 vvRkfsghknritDltfspdarWlitasmDstirtwdlpsgkl 274 +v +f gh++rit l + li++s+D tir w++ +g+ FUN_001111-T1 268 MVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWNFDTGTQ 310 6899**********************************99974 PP == domain 3 score: 4.0 bits; conditional E-value: 0.04 Beta-prop_WDR36-Utp21_2nd 170 qvvitagadkklkfwkfkskkl 191 +i+ g+d+ +++wk+ +k+ FUN_001111-T1 527 DRLISYGTDCVVRIWKLVHKEY 548 4578888888888888766653 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.0 2.2e-09 1.8e-06 70 170 .. 206 309 .. 197 347 .. 0.83 2 ? -0.1 0.0 0.63 5.4e+02 8 52 .. 404 448 .. 398 527 .. 0.60 3 ? -1.5 0.0 1.7 1.4e+03 233 274 .. 473 513 .. 466 545 .. 0.63 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 2.2e-09 WDR55 70 svskDksiavldvetgklkkkiekahespiysllvid.enllatGdddGtvklWDlRkkk..avmelkehedyisdlvvdeekklLlatsgdGtlt 162 + D ia++dv++ k ++++k e + + + + ++tGd +G ++ W + ++ +v+++ h i++l+v++e+ lL+++s d t+ FUN_001111-T1 206 LAIADVRIAMIDVASYKERRFFQKKCEFSFTCCVFFSpASYFITGDKNGSIRAWSTSLNSfpMVTQFLGHTARITKLLVHSEESLLISSSLDKTIR 301 5678999******************9999887666652779**************9988655888999**************************** PP WDR55 163 vfnirkkk 170 +n+ + + FUN_001111-T1 302 LWNFDTGT 309 99987654 PP == domain 2 score: -0.1 bits; conditional E-value: 0.63 WDR55 8 dlvvdisfhPsediiavgtidGdvllykysneenenkellslehh 52 + +vd++ P+++ i + + vl+++ +++ + ++l+ e FUN_001111-T1 404 ADIVDVAHNPRQEKIYLVLSTRAVLVFESNTNPCCAHQLWVAESP 448 566777777777777776666667766666666666666555443 PP == domain 3 score: -1.5 bits; conditional E-value: 1.7 WDR55 233 enivvtgseDGiiRavhllPnrvlgvvGqheelpvekldisk 274 ++++g+ +G i +v + g v h++ +v +l++s FUN_001111-T1 473 SGLLFAGHYNGQISLVDGKDVYMKGNVQAHQG-QVTNLKVSA 513 55556666666666666666666666666663.566666654 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.0 1.2e-08 9.9e-06 92 203 .. 234 343 .. 203 395 .. 0.81 2 ? 3.0 0.0 0.078 67 211 253 .. 498 542 .. 471 583 .. 0.67 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1.2e-08 Beta-prop_TEP1_2nd 92 avtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgc.aWtkddllvscssdGsvglWdiekeqrlgkflGhqsavs 181 + tcc f +++ tg ++ s+ W + P++++ l h +t +++ll+s+s d +++lW+ +++++ ++ + + FUN_001111-T1 234 SFTCCVFFSPASYFITGDKNGSIRAWSTSLNSFPMVTQFL--GHTARITKLlVHSEESLLISSSLDKTIRLWNFDTGTQTFRLETGEE-IV 321 679*****9*********************8888877655..5777788752678899******************999877655443.33 PP Beta-prop_TEP1_2nd 182 avvaveehvvsvgrdGllkvWd 203 + + ++ lk+W+ FUN_001111-T1 322 EMGLLSSDLLYYHSHHHLKIWS 343 3444444455555555555555 PP == domain 2 score: 3.0 bits; conditional E-value: 0.078 Beta-prop_TEP1_2nd 211 sikahsgqisq..caaalePreagqagsellvvtaGldgavklWs 253 +++ah+gq+++ +a + ++a gs +++ G+d +v++W+ FUN_001111-T1 498 NVQAHQGQVTNlkVSASVSTESADSIGSVDRLISYGTDCVVRIWK 542 556666666531134455555555555555555666666666664 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.1 1.5e-05 0.013 2 97 .. 198 295 .. 197 296 .. 0.79 2 ! 7.4 0.0 0.0037 3.2 13 37 .. 295 319 .. 293 323 .. 0.89 3 ? -1.7 0.0 2.2 1.9e+03 75 105 .. 400 430 .. 330 456 .. 0.49 4 ? 5.6 0.0 0.013 11 50 102 .. 475 526 .. 469 577 .. 0.82 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.5e-05 Beta-prop_WDR90_POC16_2nd 2 vdksrrqlatvseDetiriWdldtlqq..lydfsaseeaPcavafhPskqvfacGfssGvvrvfs..veatsllaehkqhrgkv 81 vd +++q+ + +D i + d+++++ +++ + + c+v f P + f+ G ++G +r++s +++ ++ ++ h +++ FUN_001111-T1 198 VDDASKQILAI-ADVRIAMIDVASYKErrFFQKKCEFSFTCCVFFSPAS-YFITGDKNGSIRAWStsLNSFPMVTQFLGHTARI 279 66677777666.4888889999998761145555555678*******75.789*********975227778899********** PP Beta-prop_WDR90_POC16_2nd 82 tglvfspdgeylysac 97 t l++ ++ ++l s++ FUN_001111-T1 280 TKLLVHSEESLLISSS 295 ************9985 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0037 Beta-prop_WDR90_POC16_2nd 13 seDetiriWdldtlqqlydfsasee 37 s D+tir+W+ dt +q + +++ ee FUN_001111-T1 295 SLDKTIRLWNFDTGTQTFRLETGEE 319 88****************9988776 PP == domain 3 score: -1.7 bits; conditional E-value: 2.2 Beta-prop_WDR90_POC16_2nd 75 kqhrgkvtglvfspdgeylysacslGslaly 105 ++ + ++ ++ +p e +y s+ ++ ++ FUN_001111-T1 400 TTMSADIVDVAHNPRQEKIYLVLSTRAVLVF 430 2233333333333333333333333333333 PP == domain 4 score: 5.6 bits; conditional E-value: 0.013 Beta-prop_WDR90_POC16_2nd 50 vfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgeylysacslGsl 102 ++++G +G + ++ ++ + + + h+g+vt l +s + + sa s Gs+ FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVST-ESADSIGSV 526 6899********************************9987654.566666665 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 1.9e-06 0.0016 37 160 .. 139 312 .. 110 321 .. 0.65 2 ? 1.9 0.0 0.2 1.7e+02 52 92 .. 474 514 .. 450 530 .. 0.79 3 ? 3.0 0.1 0.092 78 12 38 .. 528 553 .. 520 588 .. 0.67 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 1.9e-06 Beta-prop_EML_2 37 klekearsvafspdgkllavGl................................................kdGsvlvldaetleevvev.kdrk 81 +++ ++ s+a+++ + ++ G+ +d ++ ++d + +e + k+ + FUN_001111-T1 139 EMTRTILSLAYNEIRDEIITGIaggimtwrfpigqmdplipgqlvncsftpldwvislsvddaskqilaiADVRIAMIDVASYKERRFFqKKCE 232 5555555555555555555555555555555555555555555555555555555555555555555555666666666666555443313344 PP Beta-prop_EML_2 82 eaisdikfspdgklLavgshdnkiylYdvs.kkykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkqvt 160 + +++ f + ++ g ++++i +++s +++ v+++ gh+ +it+l +++ ++l s+s d + +w+ +tg+q FUN_001111-T1 233 FSFTCCVFFSPASYFITGDKNGSIRAWSTSlNSFPMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWNFDTGTQTF 312 45555555555677788*********99975689999**************999999***************99999865 PP == domain 2 score: 1.9 bits; conditional E-value: 0.2 Beta-prop_EML_2 52 kllavGlkdGsvlvldaetleevvevkdrkeaisdikfspd 92 ll +G +G++ ++d +++ +v+ ++ +++++k s + FUN_001111-T1 474 GLLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSAS 514 46778888888888888888888888888888888888865 PP == domain 3 score: 3.0 bits; conditional E-value: 0.092 Beta-prop_EML_2 12 qfvTagdDktvrlWdlekkklvakvkl 38 ++ g D++vr+W+l +k+ +v++ FUN_001111-T1 528 RLISYGTDCVVRIWKLVHKEY-GCVSI 553 56889**********976653.33333 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 4.7 4e+03 188 204 .. 117 133 .. 113 149 .. 0.79 2 ! 11.1 0.0 0.00023 0.2 120 173 .. 266 319 .. 241 326 .. 0.87 3 ! 11.9 0.0 0.00013 0.11 29 68 .. 522 561 .. 502 588 .. 0.77 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 4.7 Beta-prop_CAF1B_HIR1 188 atlssDrslrifdiktk 204 +t++sD s+rif++k + FUN_001111-T1 117 VTHCSDLSMRIFSAKFH 133 799*********98865 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00023 Beta-prop_CAF1B_HIR1 120 wlvlkvlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkg 173 + ++ + Gh+ + l ++++ lis+s+D t+ lW+++ g+++ l+ ++ FUN_001111-T1 266 FPMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWNFDTGTQTFRLETGEE 319 55666778***********************************99887776655 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00013 Beta-prop_CAF1B_HIR1 29 eeeevlrlasgGaDshvliWkvkieeegkvklelladltr 68 + +v rl s G+D+ v iWk+ ++e g v+++ la ++ FUN_001111-T1 522 SIGSVDRLISYGTDCVVRIWKLVHKEYGCVSIQQLARVKL 561 556889*************************999987664 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 2.3e-06 0.0019 204 304 .. 203 307 .. 198 314 .. 0.83 2 ? 2.9 0.0 0.067 57 245 304 .. 477 545 .. 464 550 .. 0.56 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 2.3e-06 Beta-prop_DCAF4 204 Geifai.dlrqrsrkgkgwkatrlfhds...avtsvqllqeeqlllaadmaGkiklwd..lratkcvkqyeGhvneyaylplhvneeeGllvav 291 +i+ai d+r ++k r+f++ + t+ + ++++ d G i+ w l + v+q+ Gh+ + l v+ ee ll++ FUN_001111-T1 203 KQILAIaDVRIAMIDVASYKERRFFQKKcefSFTCCVFFSPASYFITGDKNGSIRAWStsLNSFPMVTQFLGHTARITKLL--VHSEESLLISS 294 56777668999998999999999998762225788889999****************633778899********9988775..567899***** PP Beta-prop_DCAF4 292 Gqdcytriwslkd 304 d r+w + FUN_001111-T1 295 SLDKTIRLWNFDT 307 *********9765 PP == domain 2 score: 2.9 bits; conditional E-value: 0.067 Beta-prop_DCAF4 245 laadmaGkiklwdlratkcvkqyeGhvneyaylpl....hvneeeGl.....lvavGqdcytriwslkd 304 a G+i l d + + + + h+ + + l + ++ + + l++ G dc riw l + FUN_001111-T1 477 FAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVsasvSTESADSIgsvdrLISYGTDCVVRIWKLVH 545 55666666666655544433333333333333333110022222222223337889*********9976 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2.4 2.1e+03 28 56 .. 61 88 .. 34 147 .. 0.79 2 ! 17.8 0.1 3e-06 0.0025 171 280 .] 202 303 .. 195 303 .. 0.86 3 ? 3.2 0.0 0.082 70 217 236 .. 526 545 .. 484 560 .. 0.77 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2.4 Beta-prop_EIPR1 28 eshrFlvgtaslseeNkihlleyqdeeke 56 + h+F v+ + ++N+i + ++++++k FUN_001111-T1 61 SGHSF-VSHHGVGKKNEINVWNFSEDKKP 88 46777.46677888899999999988875 PP == domain 2 score: 17.8 bits; conditional E-value: 3e-06 Beta-prop_EIPR1 171 sslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfy 264 s+ +l+ ++ +++iD+ + k+ ++ + f+ +++v f+pa ++t +++g + + ++ + +++++ +h+ ++k l+ ++ FUN_001111-T1 202 SKQILAIADVRIAMIDVASYKERRFF--QKKCEFSFTCCVFFSPAS--YFITGDKNGSIRAWSTSLN---SFPMVTQFLGHTARITKLLVHSE- 287 556788899**************955..55556899*******975..79************87754...556678899********999886. PP Beta-prop_EIPR1 265 deLilscssdstlkLw 280 + L++s+s d+t++Lw FUN_001111-T1 288 ESLLISSSLDKTIRLW 303 78************** PP == domain 3 score: 3.2 bits; conditional E-value: 0.082 Beta-prop_EIPR1 217 knklltagddgvvlihDiRy 236 +l+++g+d+vv i+ + FUN_001111-T1 526 VDRLISYGTDCVVRIWKLVH 545 5689************9864 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.32 2.8e+02 180 211 .. 229 260 .. 197 266 .. 0.78 2 ! 18.1 0.0 2.1e-06 0.0018 8 70 .. 247 310 .. 239 329 .. 0.78 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.32 Beta-prop_WDR75_1st 180 kGaknaftcvachpkddciatGhedGkirlwr 211 k + +ftc tG ++G ir w FUN_001111-T1 229 KKCEFSFTCCVFFSPASYFITGDKNGSIRAWS 260 344567887777777777889*********96 PP == domain 2 score: 18.1 bits; conditional E-value: 2.1e-06 Beta-prop_WDR75_1st 8 fllcasGdsvkvyststee..cvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgil 70 f+ s++ +sts + +v ++ ght +t ++++ ++ l + s+sld t+rlw+f g FUN_001111-T1 247 FITGDKNGSIRAWSTSLNSfpMVTQFLGHTARITKLLVHSEESL-LISSSLDKTIRLWNFDTGTQ 310 5555556689999998775337999*************999988.5699***********87754 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 1.6 1.3e+03 313 359 .. 92 139 .. 74 147 .. 0.77 2 ! 15.6 0.0 8.4e-06 0.0072 56 135 .. 247 321 .. 218 349 .. 0.75 3 ? -0.4 0.1 0.61 5.2e+02 335 354 .. 528 547 .. 499 555 .. 0.87 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.6 Beta-prop_WDR41 313 viayqkkahdsnvlhiaklpnrql.vscsedgsvriwelrekkkssae 359 a+q + d lhi ++ r l v+ d s+ri+ + + s +e FUN_001111-T1 92 ANAFQTITTDLKFLHILFIRRRWLyVTHCSDLSMRIFSAKFHPMSITE 139 568999999999999999999987466667899999987766555555 PP == domain 2 score: 15.6 bits; conditional E-value: 8.4e-06 Beta-prop_WDR41 56 fasagddgivflwdvq..tgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdiesgrqlkkisdfqstv 135 f++ +g++ w + ++ +++ght +it + v ++ +l++++s dkt+ +w+ ++g q ++ + v FUN_001111-T1 247 FITGDKNGSIRAWSTSlnSFPMVTQFLGHTARITKLLVHSE-------ESLLISSSLDKTIRLWNFDTGTQTFRLETGEEIV 321 6666678888888765114457889*********9998654.......4699*******************98876655555 PP == domain 3 score: -0.4 bits; conditional E-value: 0.61 Beta-prop_WDR41 335 qlvscsedgsvriwelrekk 354 +l+s d vriw+l +k+ FUN_001111-T1 528 RLISYGTDCVVRIWKLVHKE 547 7999999*******998775 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 4.8 4.1e+03 236 250 .. 74 88 .. 45 97 .. 0.72 2 ? 3.1 0.1 0.085 72 90 142 .. 202 257 .. 189 285 .. 0.52 3 ! 7.1 0.0 0.0051 4.4 224 249 .. 285 310 .. 265 320 .. 0.82 4 ? 2.4 0.0 0.14 1.2e+02 130 201 .. 371 438 .. 327 458 .. 0.72 5 ? 2.3 0.0 0.15 1.3e+02 127 196 .. 471 544 .. 462 563 .. 0.62 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 4.8 Beta-prop_RIG_2nd 236 dgkvkvWdleepeke 250 ++++vW+ +e++k+ FUN_001111-T1 74 KNEINVWNFSEDKKP 88 356889999998875 PP == domain 2 score: 3.1 bits; conditional E-value: 0.085 Beta-prop_RIG_2nd 90 kkylyvvsnrelavydakkkkkeatllkkierv....slvsvrdslLlvgtedGalq 142 +k ++++++ ++a++d+ ++k+ ++k+ ++ +++ ++s+ + g ++G+++ FUN_001111-T1 202 SKQILAIADVRIAMIDVASYKERRF-FQKKCEFsftcCVFFSPASYFITGDKNGSIR 257 3445555555555555555554432.2222222112122223445555555555555 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0051 Beta-prop_RIG_2nd 224 nansnlllsfsidgkvkvWdleepek 249 ++++ ll+s+s+d ++++W+ +++++ FUN_001111-T1 285 HSEESLLISSSLDKTIRLWNFDTGTQ 310 56789****************99887 PP == domain 4 score: 2.4 bits; conditional E-value: 0.14 Beta-prop_RIG_2nd 130 slLlvgtedGalqllerkkelekayskllkqeallsryitdiawsplesnklAvvandkvivilefkeeern 201 + l+ +edG ++ll+ +++e + + +++s i d+a +p + +k+ v ++ + ++e +++ + FUN_001111-T1 371 ARVLLHSEDGGVRLLSPVHGSEL--T-AVLPITTMSADIVDVAHNPRQ-EKIYLVLSTRAVLVFESNTNPCC 438 44556789999999999998884..3.35678899999*******998.77777788889999998876554 PP == domain 5 score: 2.3 bits; conditional E-value: 0.15 Beta-prop_RIG_2nd 127 vrdslLlvgtedGalqllerkkelekaysk....llkqeallsryitdiawsplesnklAvvandkvivilefk 196 ++ lL+ g +G+++l++ k+ ++k + +++ +++++ t++a s + + l + d+v+ i ++ FUN_001111-T1 471 LKSGLLFAGHYNGQISLVDGKDVYMKGNVQahqgQVTNLKVSASVSTESADSIGSVDRLISYGTDCVVRIWKLV 544 56678999999999999999976665544300003333344444444444444444777777777777776664 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.4 1.2e+03 58 64 .. 106 112 .. 60 147 .. 0.51 2 ? -0.8 0.0 0.94 8e+02 19 39 .. 243 263 .. 238 284 .. 0.70 3 ! 8.5 0.0 0.0014 1.2 20 43 .. 288 311 .. 273 334 .. 0.72 4 ? 3.7 0.0 0.041 35 103 157 .. 476 530 .. 468 550 .. 0.89 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.4 WD40_MABP1-WDR62_2nd 58 kvlyvde 64 ++l++ + FUN_001111-T1 106 HILFIRR 112 3333322 PP == domain 2 score: -0.8 bits; conditional E-value: 0.94 WD40_MABP1-WDR62_2nd 19 pagsFltcssDdtiRlWnlee 39 pa+ F+t + +iR W+++ FUN_001111-T1 243 PASYFITGDKNGSIRAWSTSL 263 556677777777777777654 PP == domain 3 score: 8.5 bits; conditional E-value: 0.0014 WD40_MABP1-WDR62_2nd 20 agsFltcssDdtiRlWnleeksse 43 ++ +++s D+tiRlWn ++ +++ FUN_001111-T1 288 ESLLISSSLDKTIRLWNFDTGTQT 311 445789999*********976543 PP == domain 4 score: 3.7 bits; conditional E-value: 0.041 WD40_MABP1-WDR62_2nd 103 lasGDrsGniriydletleellkieahdsevlcleyskpetglkllasasRDRli 157 l +G +G+i + d + + +++ah+++v l+ s + + + + +s DRli FUN_001111-T1 476 LFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASVSTESADSIGSVDRLI 530 66899999999999999999999**********9999999998888899999998 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.1 3.8e-05 0.032 1 34 [. 275 310 .. 275 323 .. 0.84 2 ? 1.4 0.1 0.52 4.4e+02 13 30 .. 527 544 .. 502 583 .. 0.82 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 3.8e-05 Beta-prop_TEP1_C 1 hsdrisalkl..tddliisAseDrtvKlWdretkkq 34 h+ ri++l + ++l+is+s D+t++lW+ +t q FUN_001111-T1 275 HTARITKLLVhsEESLLISSSLDKTIRLWNFDTGTQ 310 7889998865115899*************9988765 PP == domain 2 score: 1.4 bits; conditional E-value: 0.52 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdre 30 d +is +D v++W+ FUN_001111-T1 527 DRLISYGTDCVVRIWKLV 544 568899999999999864 PP >> WDR54 WDR54 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 1.1 9.7e+02 227 282 .. 249 306 .. 218 318 .. 0.75 2 ! 14.7 0.1 2e-05 0.017 211 289 .. 462 550 .. 404 582 .. 0.80 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.1 WDR54 227 agygngqvhlyeattgn..lhvqinaharaicaldlasevgkllsagedtfvhiwkls 282 +g ng ++ + ++ + q h+ i l + se l+s+ d +++w++ FUN_001111-T1 249 TGDKNGSIRAWSTSLNSfpMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWNFD 306 5666666666665544311456888999999999999999999999999999999876 PP == domain 2 score: 14.7 bits; conditional E-value: 2e-05 WDR54 211 fgvpcpsvqlwqgiiaagygngqvhlyeattgnlhvqinaharaicaldlas...........evgkllsagedtfvhiwklsrnpesgy 289 f + + l g++ ag+ ngq+ l + ++ +++ah + l +++ v +l+s g d +v+iwkl ++ e g FUN_001111-T1 462 FALEKGEIPLKSGLLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSAsvstesadsigSVDRLISYGTDCVVRIWKLVHK-EYGC 550 566666778899***************9999888888888888777776543111111111114679***************864.4555 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 4.1e-05 0.035 361 460 .. 248 350 .. 236 360 .. 0.79 2 ? 1.1 0.1 0.22 1.9e+02 362 413 .. 478 527 .. 469 563 .. 0.70 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 4.1e-05 Beta-prop_SCAP 361 asGGqdGaiclwdvltGs..rvshvyghrGdvtslvct..tscvissGlddlisiwdrstgiklysiqqevGcGaslGvisdnllvtGGqGcvsf 451 +G ++G+i w s v+ gh +t l++ s +iss ld i +w+ tg + + + +G++s +ll + + FUN_001111-T1 248 ITGDKNGSIRAWSTSLNSfpMVTQFLGHTARITKLLVHseESLLISSSLDKTIRLWNFDTGTQTFRLETGEEI-VEMGLLSSDLLYYHSHHHLKI 341 57889999999987666534799***********987522699******************999987654333.578999999999888888888 PP Beta-prop_SCAP 452 wdlnyGdll 460 w ln l FUN_001111-T1 342 WSLNLFHSL 350 888865555 PP == domain 2 score: 1.1 bits; conditional E-value: 0.22 Beta-prop_SCAP 362 sGGqdGaiclwdvltGsrvshvyghrGdvtslvcttscvissGlddlisiwd 413 +G +G i l d v +h+G+vt l +++s+ s+ d i d FUN_001111-T1 478 AGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSASV--STESADSIGSVD 527 56667777777776666677888999999999887773..333334444444 PP >> Beta-prop_IP5PC_F IP5P C-F beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.0001 0.087 58 153 .. 228 319 .. 216 334 .. 0.77 2 ? -1.4 0.1 1.3 1.1e+03 106 121 .. 498 513 .. 472 543 .. 0.54 3 ? -2.2 0.0 2.4 2e+03 13 37 .. 523 547 .. 517 585 .. 0.65 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0001 Beta-prop_IP5PC_F 58 aesastsptlclvvdegsklvwsGhkdGkirswkmdqssddtsfkeglswqahrgpvlslvissyGd.lwsgsegGvikvwpwesiekslsl 148 ++ + s t c+ + + +G k+G ir+w + +sf + h + + l + s l s+s + +i++w +++ +++ l FUN_001111-T1 228 QKKCEFSFTCCVF-FSPASYFITGDKNGSIRAWSTSL----NSFPMVTQFLGHTARITKLLVHSEESlLISSSLDKTIRLWNFDTGTQTFRL 314 4444455555555.555556679**********8754....5788888999999999998887766516789999**********9999999 PP Beta-prop_IP5PC_F 149 saeer 153 ++ e FUN_001111-T1 315 ETGEE 319 88775 PP == domain 2 score: -1.4 bits; conditional E-value: 1.3 Beta-prop_IP5PC_F 106 swqahrgpvlslviss 121 qah+g+v l +s+ FUN_001111-T1 498 NVQAHQGQVTNLKVSA 513 2345555555555444 PP == domain 3 score: -2.2 bits; conditional E-value: 2.4 Beta-prop_IP5PC_F 13 iactetqlwaGqesGvrvwnfsday 37 i + + + G+++ vr+w++ + FUN_001111-T1 523 IGSVDRLISYGTDCVVRIWKLVHKE 547 5666777778999999999986543 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.1 5.6e-05 0.048 147 222 .. 236 312 .. 219 323 .. 0.78 2 ? -3.0 0.0 4.6 3.9e+03 284 334 .. 475 522 .. 469 528 .. 0.70 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.6e-05 WD40_Gbeta 147 sccrfldd.nqivtssgdttcalwd..ietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtf 222 +cc f+ +t + + w +++ t f ght + l + + l++s + d +++lw+ g+ qtf FUN_001111-T1 236 TCCVFFSPaSYFITGDKNGSIRAWStsLNSFPMVTQFLGHTARITKLLVHSEESLLISSSLDKTIRLWNFDTGT--QTF 312 677777651557888777888888622445567899********************************987765..444 PP == domain 2 score: -3.0 bits; conditional E-value: 4.6 WD40_Gbeta 284 lllagyddfncnvwdalkadragvlaghdnrvsclgvtddgmavatgswds 334 ll+ag+ + + + d g + h+ +v+ l v++ v+t s ds FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLKVSAS---VSTESADS 522 7778877777888888888888888888888888887653...45555444 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.022 19 36 86 .. 274 323 .. 257 327 .. 0.88 2 ? 2.3 0.0 0.34 2.9e+02 52 87 .. 475 510 .. 471 514 .. 0.89 3 ? -0.2 0.0 2 1.7e+03 49 65 .. 571 587 .. 567 590 .. 0.68 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.022 ANAPC4_WD40 36 kedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdkitcl 86 ++++++t+l + ++ lL+ + d ++rl + +g+ l+++++ i+ + FUN_001111-T1 274 GHTARITKLLVHSEESLLISSSLDKTIRLWNFDTGTQTFRLETGEE-IVEM 323 57789********************************999999998.6665 PP == domain 2 score: 2.3 bits; conditional E-value: 0.34 ANAPC4_WD40 52 lLavaysdgevrlldvesgklvhslsaksdkitcle 87 lL ++ +g+++l+d ++ + +++a++ ++t l+ FUN_001111-T1 475 LLFAGHYNGQISLVDGKDVYMKGNVQAHQGQVTNLK 510 78899****************999*99999998875 PP == domain 3 score: -0.2 bits; conditional E-value: 2 ANAPC4_WD40 49 dGklLavaysdgevrll 65 G+ L++a++d++v ++ FUN_001111-T1 571 AGNTLCMAMADNNVIMC 587 57777777777776554 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 1.2 1e+03 108 132 .. 235 259 .. 205 267 .. 0.81 2 ? 10.3 0.1 0.00051 0.44 61 96 .. 275 309 .. 262 320 .. 0.84 3 ? -1.8 0.0 2.4 2e+03 119 137 .. 475 493 .. 472 531 .. 0.77 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1.2 WD40_RFWD3 108 WsCcWseddsnylyaGlqnGsvlvf 132 +Cc + y+ +G +nGs+ + FUN_001111-T1 235 FTCCVFFSPASYFITGDKNGSIRAW 259 57888889999**********9876 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00051 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsnt 96 H+ +i l +se +sll+s slDkt++l ++ + t FUN_001111-T1 275 HTARITKLLVHSE-ESLLISSSLDKTIRLWNFDTGT 309 9999999999988.9**************9997765 PP == domain 3 score: -1.8 bits; conditional E-value: 2.4 WD40_RFWD3 119 ylyaGlqnGsvlvfDiRqt 137 +l+aG nG++ + D +++ FUN_001111-T1 475 LLFAGHYNGQISLVDGKDV 493 689*******999887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (594 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 606 (0.0237228); expected 510.9 (0.02) Passed bias filter: 535 (0.0209434); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 30 (0.0011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 30 [number of targets reported over threshold] # CPU time: 0.43u 0.38s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 5518.15 // Query: FUN_001112-T1 [L=1362] Description: FUN_001112 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-05 24.3 0.1 0.00044 21.0 0.0 2.5 2 HEAT_2 HEAT repeats 0.00069 20.1 0.1 0.02 15.6 0.0 3.3 3 HEAT HEAT repeat 0.001 18.9 0.0 0.0019 18.0 0.0 1.3 1 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 0.0017 19.3 0.5 0.0045 18.0 0.5 1.7 1 WD40 WD domain, G-beta repeat ------ inclusion threshold ------ 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 Beta-prop_EML_2 Echinoderm microtubule-associated protein 0.011 17.0 3.3 3.8 8.8 0.2 3.2 2 SH3-A_UBE2O UBE2O, N-terminal SH3-A domain 0.017 14.9 0.0 0.029 14.1 0.0 1.2 1 Beta-prop_WDR5 WDR5 beta-propeller domain 0.028 14.6 0.0 0.055 13.6 0.0 1.5 1 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 0.056 12.9 0.0 0.095 12.2 0.0 1.3 1 Beta-prop_THOC3 THOC3 beta-propeller domain 0.15 13.1 0.1 1.7 9.8 0.0 2.6 2 HEAT_EZ HEAT-like repeat 0.36 11.4 3.5 1.9 9.1 0.0 3.2 3 TrbK Conjugative transfer region protein TrbK Domain annotation for each model (and alignments): >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 1.9e-07 0.00044 4 56 .. 553 606 .. 542 622 .. 0.74 2 ? -0.6 0.0 1 2.4e+03 14 44 .. 1240 1270 .. 1236 1274 .. 0.79 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1.9e-07 HEAT_2 4 LlqaLlkdpdpevraaairaLg..eigdpealpaLlellkdedpavRraaakaLg 56 L+++ +d+d +r++a+r Lg e+ +++a ++++ l d+d+ +R++a kaL FUN_001112-T1 553 LVKMC-HDEDATIRQTAVRLLGemEVHRKDAYLTVVRRLVDDDKKTREEAKKALH 606 56666.7888888888888888666677788888888888888888888877775 PP == domain 2 score: -0.6 bits; conditional E-value: 1 HEAT_2 14 pevraaairaLgeigdpealpaLlellkded 44 pe r + ra ++ +e+l+aL +++k+ + FUN_001112-T1 1240 PENRLNLFRAVNGMNKQESLAALAKYIKNQN 1270 5667777788888888899999988887765 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 2.2 5.1e+03 5 21 .. 72 88 .. 70 89 .. 0.80 2 ! 15.6 0.0 8.7e-06 0.02 3 27 .. 551 575 .. 549 576 .. 0.92 3 ? -0.5 0.0 1.3 3.1e+03 6 28 .. 587 609 .. 585 611 .. 0.86 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 2.2 HEAT 5 llkllnDpspeVReaAa 21 ++k n+ + VRe+++ FUN_001112-T1 72 CVKIWNSNNQLVREMCF 88 56656999******996 PP == domain 2 score: 15.6 bits; conditional E-value: 8.7e-06 HEAT 3 plllkllnDpspeVReaAaeaLgal 27 +ll+k+++D+++ +R++A++ Lg++ FUN_001112-T1 551 NLLVKMCHDEDATIRQTAVRLLGEM 575 789********************86 PP == domain 3 score: -0.5 bits; conditional E-value: 1.3 HEAT 6 lkllnDpspeVReaAaeaLgala 28 ++ l D++ + Re A +aL +l+ FUN_001112-T1 587 VRRLVDDDKKTREEAKKALHTLT 609 67789*************99885 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 8.2e-07 0.0019 172 256 .. 44 124 .. 23 135 .. 0.71 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 8.2e-07 WD40_CDC20-Fz 172 kltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgsqvtsllwskeekelvsthgysknqivlwkypslk 256 k + h+a + l+ c +l at + +D+++++wn n ++l++++ + +++ +++++ ++++++ y+ + +++ +y l+ FUN_001112-T1 44 KDEGHTALINGLSCCS-TLGLFATSS--EDHCVKIWNSN-NQLVREMCFDESLCGVCFANSRGDILVGFQYHISLVTILNYLPLT 124 3346777777777666.447777754..78888888866.778888888888888888888888888888888888888876665 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.5 1.9e-06 0.0045 8 39 .] 46 77 .. 39 77 .. 0.90 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 1.9e-06 WD40 8 kgHtsgVtslafspdgsllasgsdDgtvklWd 39 +gHt+ +++l+ +++ l+a++s+D++vk+W+ FUN_001112-T1 46 EGHTALINGLSCCSTLGLFATSSEDHCVKIWN 77 69*777****99999999*************7 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 7.5e-06 0.017 3 59 .. 54 109 .. 52 136 .. 0.90 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 7.5e-06 Beta-prop_EML_2 3 GLathpsepqfvTagdDktvrlWdlekkklvakvklekearsvafspdgkllavGlk 59 GL++ + f+T ++D+ v +W+ +++lv+++ +++++ v+f ++ + vG++ FUN_001112-T1 54 GLSCCSTLGLFATSSEDHCVKIWNS-NNQLVREMCFDESLCGVCFANSRGDILVGFQ 109 99999999****************5.899**************************97 PP >> SH3-A_UBE2O UBE2O, N-terminal SH3-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.2 0.0017 3.8 26 79 .. 431 494 .. 421 499 .. 0.61 2 ? 7.1 0.3 0.0058 13 18 44 .. 1032 1058 .. 1025 1086 .. 0.59 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0017 SH3-A_UBE2O 26 eeedsedsdeddddddegGgggee............egssdsesaaeesrarplkrgfvrvqwype 79 +e++se+s+ ++++e+Gg +e ++ s+ + + s+ pl vr wyp FUN_001112-T1 431 DESESEQSEI--EEENEEGGILDEilgespspadekQNTSNVMQVSVTSSDLPLLTRIVRKTWYPK 494 4555555554..444444433333333345555556555555555567778899999999999996 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0058 SH3-A_UBE2O 18 GlVrlihgeeedsedsdeddddddegG 44 G+ l++ ee++e+++e++++++e+ FUN_001112-T1 1032 GICALVEPHEEEEEEEEEEEEEEEEQQ 1058 666666554444444444444444332 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.0 1.2e-05 0.029 35 92 .. 36 92 .. 21 126 .. 0.74 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.2e-05 Beta-prop_WDR5 35 veegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtny 92 ++e+ ++++ egh++ i+ ++ s l a++S+D+ v+iw+ ++ +l++++ ++ FUN_001112-T1 36 THEFLTHSKDEGHTALINGLSCCSTLGLFATSSEDHCVKIWNSNN-QLVREMCFDESL 92 344445666789*****************************9875.566766544444 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 2.4e-05 0.055 110 151 .. 46 87 .. 40 120 .. 0.89 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.4e-05 Beta-prop_WDR3_1st 110 kgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktl 151 +gH+ ++ ++ +++ + ++sS+D+++k+W+ ++q + + FUN_001112-T1 46 EGHTALINGLSCCSTLGLFATSSEDHCVKIWNSNNQLVREMC 87 79******************************9998776665 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 4.1e-05 0.095 37 98 .. 40 99 .. 24 138 .. 0.68 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 4.1e-05 Beta-prop_THOC3 37 sketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgeninlawsp 98 ++++ +ght ++ l++ t l+at+s+D++v++W+ ++ + ++++ +++ +++ + FUN_001112-T1 40 LTHSKDEGHTALINGLSCCSTL-GLFATSSEDHCVKIWNSNN-QLVREMCFDESLCGVCFAN 99 2344557888888888887775.5888888888888888654.4555555555555555555 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.0 0.00073 1.7 32 54 .. 551 574 .. 548 575 .. 0.82 2 ? 0.1 0.0 0.82 1.9e+03 25 48 .. 578 601 .. 574 605 .. 0.81 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00073 HEAT_EZ 32 lLlplLndddd.eVReaAawaLgr 54 Ll+++++d+d ++R++A++ Lg+ FUN_001112-T1 551 NLLVKMCHDEDaTIRQTAVRLLGE 574 58889999999455*********8 PP == domain 2 score: 0.1 bits; conditional E-value: 0.82 HEAT_EZ 25 llpellplLlplLnddddeVReaA 48 + +++ + +++L ddd+++Re A FUN_001112-T1 578 HRKDAYLTVVRRLVDDDKKTREEA 601 667888889999999999***977 PP >> TrbK Conjugative transfer region protein TrbK # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.00081 1.9 47 76 .. 49 79 .. 29 81 .. 0.75 2 ? -3.1 0.1 4.9 1.1e+04 26 55 .. 646 676 .. 637 676 .. 0.62 3 ? 1.0 0.4 0.27 6.4e+02 20 56 .. 1033 1067 .. 1018 1071 .. 0.57 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00081 TrbK 47 DpLraelrrCqqlg.eaaaedaeClrvWaen 76 L + l C++lg a+ ++++C ++W n FUN_001112-T1 49 TALINGLSCCSTLGlFATSSEDHCVKIWNSN 79 46889999******77778899******988 PP == domain 2 score: -3.1 bits; conditional E-value: 4.9 TrbK 26 ltrkeeepaaesaaaaeaeaa.DpLraelrr 55 l++ +++++e ++ +++++ +Lr++lrr FUN_001112-T1 646 LRNAGKAKKEEDHENDQRKSSlGNLRSTLRR 676 3333366666666677777777899999987 PP == domain 3 score: 1.0 bits; conditional E-value: 0.27 TrbK 20 tatvieltrkeeepaaesaaaaeaeaaDpLraelrrC 56 + +++e +++eee+++e+++++e++ + ++++ C FUN_001112-T1 1033 ICALVEPHEEEEEEEEEEEEEEEEQ--QQQQQQQFSC 1067 5566666666654443333333333..3446777777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2413 (0.0944608); expected 510.9 (0.02) Passed bias filter: 1016 (0.0397729); expected 510.9 (0.02) Passed Vit filter: 126 (0.00493247); expected 25.5 (0.001) Passed Fwd filter: 28 (0.0010961); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.59u 0.43s 00:00:01.02 Elapsed: 00:00:00.44 # Mc/sec: 12448.63 // Query: FUN_001112-T2 [L=969] Description: FUN_001112 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-05 25.1 0.1 0.00029 21.5 0.0 2.5 2 HEAT_2 HEAT repeats 0.00084 19.9 0.0 0.014 16.1 0.0 2.7 2 HEAT HEAT repeat ------ inclusion threshold ------ 0.019 15.9 2.2 0.019 15.9 2.2 2.9 2 CENP-B_dimeris Centromere protein B dimerisation domain 0.08 14.0 0.2 1.2 10.3 0.0 2.7 2 HEAT_EZ HEAT-like repeat 0.13 13.5 8.0 2.5 9.4 0.2 3.3 3 SH3-A_UBE2O UBE2O, N-terminal SH3-A domain 0.21 10.6 4.3 0.5 9.3 4.3 1.6 1 P22_portal Phage P22-like portal protein 3.3 8.1 7.0 0.17 12.3 0.3 2.4 2 eIF_4EBP Eukaryotic translation initiation factor 4E b Domain annotation for each model (and alignments): >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 8e-08 0.00029 4 56 .. 160 213 .. 149 229 .. 0.74 2 ? 0.1 0.0 0.4 1.5e+03 14 44 .. 847 877 .. 838 882 .. 0.81 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 8e-08 HEAT_2 4 LlqaLlkdpdpevraaairaLg..eigdpealpaLlellkdedpavRraaakaLg 56 L+++ +d+d +r++a+r Lg e+ +++a ++++ l d+d+ +R++a kaL FUN_001112-T2 160 LVKMC-HDEDATIRQTAVRLLGemEVHRKDAYLTVVRRLVDDDKKTREEAKKALH 213 56666.7888888888888888666677788888888888888888888877775 PP == domain 2 score: 0.1 bits; conditional E-value: 0.4 HEAT_2 14 pevraaairaLgeigdpealpaLlellkded 44 pe r + ra ++ +e+l+aL +++k+ + FUN_001112-T2 847 PENRLNLFRAVNGMNKQESLAALAKYIKNQN 877 5667777788888888888999888888765 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 3.7e-06 0.014 3 27 .. 158 182 .. 156 183 .. 0.92 2 ? 0.0 0.0 0.57 2.1e+03 6 28 .. 194 216 .. 192 218 .. 0.86 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 3.7e-06 HEAT 3 plllkllnDpspeVReaAaeaLgal 27 +ll+k+++D+++ +R++A++ Lg++ FUN_001112-T2 158 NLLVKMCHDEDATIRQTAVRLLGEM 182 789********************86 PP == domain 2 score: 0.0 bits; conditional E-value: 0.57 HEAT 6 lkllnDpspeVReaAaeaLgala 28 ++ l D++ + Re A +aL +l+ FUN_001112-T2 194 VRRLVDDDKKTREEAKKALHTLT 216 67789*************99885 PP >> CENP-B_dimeris Centromere protein B dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 8.5 2.4 8.9e+03 9 39 .. 25 55 .. 19 71 .. 0.81 2 ? 15.9 2.2 5.3e-06 0.019 15 54 .. 650 689 .. 642 709 .. 0.66 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 2.4 CENP-B_dimeris 9 gedsdsdsdeeeddeeedeededeeddedgd 39 ed + e+ +de e e+ e ee++e+g FUN_001112-T2 25 YEDVSKENAENIQDESESEQSEIEEENEEGG 55 5777788889999999999999999999884 PP == domain 2 score: 15.9 bits; conditional E-value: 5.3e-06 CENP-B_dimeris 15 dsdeeeddeeedeededeeddedgdevpvpsfgeamayfa 54 + +eee++eee+ee++++++++ evp p++g +m +a FUN_001112-T2 650 EEEEEEEEEEEEEEQQQQQQQQFSCEVPQPTLGMSMVPVA 689 33334444444444444455566789*******9998766 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.00032 1.2 32 54 .. 158 181 .. 155 182 .. 0.82 2 ? 0.6 0.0 0.36 1.3e+03 25 48 .. 185 208 .. 181 212 .. 0.81 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00032 HEAT_EZ 32 lLlplLndddd.eVReaAawaLgr 54 Ll+++++d+d ++R++A++ Lg+ FUN_001112-T2 158 NLLVKMCHDEDaTIRQTAVRLLGE 181 58889999999455*********8 PP == domain 2 score: 0.6 bits; conditional E-value: 0.36 HEAT_EZ 25 llpellplLlplLnddddeVReaA 48 + +++ + +++L ddd+++Re A FUN_001112-T2 185 HRKDAYLTVVRRLVDDDKKTREEA 208 667888889999999999***977 PP >> SH3-A_UBE2O UBE2O, N-terminal SH3-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.2 0.00069 2.5 26 79 .. 38 101 .. 28 106 .. 0.61 2 ? -4.4 0.1 7 2.6e+04 32 39 .. 262 269 .. 256 278 .. 0.44 3 ? 7.6 0.3 0.0025 9.1 18 44 .. 639 665 .. 632 693 .. 0.59 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00069 SH3-A_UBE2O 26 eeedsedsdeddddddegGgggee............egssdsesaaeesrarplkrgfvrvqwype 79 +e++se+s+ ++++e+Gg +e ++ s+ + + s+ pl vr wyp FUN_001112-T2 38 DESESEQSEI--EEENEEGGILDEilgespspadekQNTSNVMQVSVTSSDLPLLTRIVRKTWYPK 101 4555555554..444444433333333345555556555555555567778899999999999996 PP == domain 2 score: -4.4 bits; conditional E-value: 7 SH3-A_UBE2O 32 dsdedddd 39 ++d+++d+ FUN_001112-T2 262 EEDHENDQ 269 22222222 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0025 SH3-A_UBE2O 18 GlVrlihgeeedsedsdeddddddegG 44 G+ l++ ee++e+++e++++++e+ FUN_001112-T2 639 GICALVEPHEEEEEEEEEEEEEEEEQQ 665 666666554444444444444444332 PP >> P22_portal Phage P22-like portal protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 4.3 0.00014 0.5 555 579 .. 646 671 .. 627 690 .. 0.59 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00014 P22_portal 555 pde.eeeqqeaqaaqqqqqqqqqpqm 579 p e eee++e++++++++qqqqq+q+ FUN_001112-T2 646 PHEeEEEEEEEEEEEEEEQQQQQQQQ 671 44423333332222222222222222 PP >> eIF_4EBP Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.2 1.5 6.1 2.2e+04 92 105 .. 32 45 .. 19 53 .. 0.35 2 ? 12.3 0.3 4.6e-05 0.17 60 116 .. 615 675 .. 612 676 .. 0.78 Alignments for each domain: == domain 1 score: -4.2 bits; conditional E-value: 6.1 eIF_4EBP 92 kkeaekkeekeeke 105 ++e+ ++e+++e++ FUN_001112-T2 32 NAENIQDESESEQS 45 11111111111111 PP == domain 2 score: 12.3 bits; conditional E-value: 4.6e-05 eIF_4EBP 60 rnSPlaktPPsnlpkiPgvtsk....ekkkekkekekkeaekkeekeekekkeeeeqfemd 116 n Pla++ P++ ++ +v++ + e +e+e++e+e++ee+ee++++++++qf+ + FUN_001112-T2 615 NNGPLARSNPKRSRRLNEVLKGilgiCALVEPHEEEEEEEEEEEEEEEEQQQQQQQQFSCE 675 589*********9999999988888755556666666666777888888889999999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (969 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2198 (0.0860442); expected 510.9 (0.02) Passed bias filter: 984 (0.0385203); expected 510.9 (0.02) Passed Vit filter: 113 (0.00442357); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.48u 0.42s 00:00:00.89 Elapsed: 00:00:00.42 # Mc/sec: 9224.16 // Query: FUN_001113-T1 [L=260] Description: FUN_001113 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (260 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1050 (0.0411039); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2606.92 // Query: FUN_001114-T1 [L=219] Description: FUN_001114 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-45 152.6 0.0 9.4e-45 152.3 0.0 1.1 1 NDK Nucleoside diphosphate kinase 6.6e-18 64.6 0.3 1.2e-17 63.8 0.3 1.4 1 Dpy-30 Dpy-30 motif ------ inclusion threshold ------ 0.2 12.4 0.0 3 8.7 0.0 2.2 2 DUF7779 Domain of unknown function (DUF7779) Domain annotation for each model (and alignments): >> NDK Nucleoside diphosphate kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.3 0.0 1.1e-48 9.4e-45 1 133 [. 18 151 .. 18 153 .. 0.97 Alignments for each domain: == domain 1 score: 152.3 bits; conditional E-value: 1.1e-48 NDK 1 ertlvliKPdavqrgligeiisrlekkglkivalkmlqlteeqaeefYaehkekpffeelvefmtsgpvvalvlegenavkkvreliGatnpaea. 95 ertl+liKPdav+ + +ei + + ++g++i++ + +++t eq ++fYaeh +k+ff++lv++m+sgp +a+vl+++ a++ +r+liG+tn ++a FUN_001114-T1 18 ERTLALIKPDAVH--KSDEIEEIILQHGFTILQKRRVHMTPEQTSDFYAEHYGKMFFPSLVAYMSSGPTLAIVLAKQSAITYWRQLIGPTNTQKAr 111 8***********6..67*****************************************************************************99 PP NDK 96 ..apgtiRadfavsieeNavHgSdseesaereialfFkee 133 ap+++Ra ++++ ++Na+HgSds saerei++fF+++ FUN_001114-T1 112 dqAPESLRAIYGTDSTKNALHGSDSYSSAEREIHFFFPDS 151 99***********************************975 PP >> Dpy-30 Dpy-30 motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.8 0.3 1.4e-21 1.2e-17 2 42 .] 162 202 .. 161 202 .. 0.96 Alignments for each domain: == domain 1 score: 63.8 bits; conditional E-value: 1.4e-21 Dpy-30 2 arkYLnktvaPiLlqGLtelAkeRPeDPieyLAeYLlknkn 42 a++YL tv+P+Ll+GLtel+k++P DPi +L ++L+ n++ FUN_001114-T1 162 AKDYLTRTVTPTLLKGLTELCKKKPADPILWLSDWLIANNP 202 89***********************************9986 PP >> DUF7779 Domain of unknown function (DUF7779) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.0 0.00035 3 10 71 .. 20 80 .. 15 89 .. 0.75 2 ? 1.2 0.0 0.071 6.1e+02 17 38 .. 144 165 .. 141 182 .. 0.77 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00035 DUF7779 10 araLlevlsfldPDsIpEeiLeqeaaveaekdglpeaypkteeeyiearaeLlqsSLikrnk 71 ++aL++ ++ +D+I+E iL+++ ++ +++ + ++ +t+ y e ++ SL+ + FUN_001114-T1 20 TLALIKPDAVHKSDEIEEIILQHGFTILQKR-RVHMTPEQTSDFYAEHYGKMFFPSLVAYMS 80 5677777788999********9998776554.566676777777888888888888887665 PP == domain 2 score: 1.2 bits; conditional E-value: 0.071 DUF7779 17 lsfldPDsIpEeiLeqeaavea 38 + f+ PDsI E i +++aa++ FUN_001114-T1 144 IHFFFPDSIVEPISTGQAAKDY 165 56999*******9998776554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 403 (0.0157761); expected 510.9 (0.02) Passed bias filter: 386 (0.0151106); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 2117.94 // Query: FUN_001115-T1 [L=91] Description: FUN_001115 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-18 66.6 0.4 2.3e-18 66.2 0.4 1.2 1 LSM LSM domain ------ inclusion threshold ------ 0.016 15.3 0.0 0.03 14.4 0.0 1.5 1 Hfq Hfq protein Domain annotation for each model (and alignments): >> LSM LSM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.2 0.4 1.8e-22 2.3e-18 2 64 .. 22 85 .. 21 87 .. 0.95 Alignments for each domain: == domain 1 score: 66.2 bits; conditional E-value: 1.8e-22 LSM 2 fLkkllgkrvlvelkngrelrGtLkgfDqfmNlvLddveetikdg.ekrklglvliRGnnivli 64 +L++ + ++++ + +++++G+++gfD++mNlvLdd+ee++ ++ ++r+lg++l++G+ni+l+ FUN_001115-T1 22 YLQNRSRIQIWLYEQVNMRIEGHIIGFDEYMNLVLDDAEEVHLKTkKRRPLGRILLKGDNITLL 85 68999999*********************************988889***************97 PP >> Hfq Hfq protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 2.3e-06 0.03 11 44 .. 26 60 .. 19 67 .. 0.66 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.3e-06 Hfq 11 kekievtvfLvnGvklkGviksfDnft.vlleseg 44 +++i++ + ++++G+i +fD+++ ++l++ + FUN_001115-T1 26 RSRIQIWLYEQVNMRIEGHIIGFDEYMnLVLDDAE 60 33444444444567899*********934445444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (91 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 556 (0.0217655); expected 510.9 (0.02) Passed bias filter: 436 (0.0170679); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 921.29 // Query: FUN_001116-T1 [L=1067] Description: FUN_001116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-22 77.9 21.2 9.2e-22 77.9 21.2 2.5 3 MRVI1 MRVI1 protein ------ inclusion threshold ------ 0.67 11.0 6.7 0.21 12.6 2.9 2.2 2 DUF5945 Family of unknown function (DUF5945) Domain annotation for each model (and alignments): >> MRVI1 MRVI1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.1 4.0 1.1 1.4e+04 175 183 .. 144 152 .. 35 249 .. 0.43 2 ? -3.8 2.9 0.43 5.5e+03 118 194 .. 257 330 .. 212 352 .. 0.52 3 ! 77.9 21.2 7.2e-26 9.2e-22 73 450 .. 581 980 .. 562 1039 .. 0.76 Alignments for each domain: == domain 1 score: -5.1 bits; conditional E-value: 1.1 MRVI1 175 vrksentsa 183 +r+ ++ +a FUN_001116-T1 144 LRQIDELAA 152 222222222 PP == domain 2 score: -3.8 bits; conditional E-value: 0.43 MRVI1 118 spafkdlqlqvs....llreknlvgleakelsetveeekkesaagedvvsslpdvlvkkvrvrksentsatekevEaeFlr 194 af + + ++++ ++ e + ls+++e+ek+ s + ed++ s+ + +++ +++ ke E+e l+ FUN_001116-T1 257 ELAFLE-----QqlskVTEDLFKIRDEKESLSRSLENEKRLSSSLEDELVSIRKS-QDELESQQTI-LLVRIKELESELLK 330 222222.....22222555555566666677777777777777777776666532.2333333322.23345555555555 PP == domain 3 score: 77.9 bits; conditional E-value: 7.2e-26 MRVI1 73 estvtssdsrsellrmasgDsdckelcekeeekrsaskaaekqlkspafkdlqlqvsllreknlvgleakelsetveeekk....esaagedvvss 164 estv + + r sg s++ +++ e++s ++ + +++ks +++ ++l l +ek++ +l k+ls + ++ sa+ge+ s FUN_001116-T1 581 ESTVENLNGDQRQRRRKSGLSGSLLTADTATETKSDANESASKSKSETIDSTKLCPVLEKEKKATNLWRKKLSVAFKTPEEfepySSATGEALEDS 676 55555555556666667777777777788889999999999999999*******999999999999999999887766555556688888888888 PP MRVI1 165 lpdvlvkkvrvrksentsatekevEaeFlrLsLafkcDsftLEkRvkleERsRdLaEEnlkkEltnflkllesltsLcEddnqarEiikkLekdia 260 + v v +r + +eke+E +F L Laf++D tL++R++ + RsRd+aE n+ kEl+ + +ll+ +Lc + ++++ L++++ FUN_001116-T1 677 VGSNFVDGVSLRVR--PAPNEKEIEKQFRTLVLAFHTDQDTLNRRLEVQSRSRDVAESNMSKELQSMSNLLKDFEQLCIT-RDMQDMLSSLKSQVE 769 88888887777643..3459**********************************************************99.899************ PP MRVI1 261 vLsrlaaRlasRAEmlGAirqEsRvskAvEvmiqyvEnLkRmYakeHAELeel..kkvllqneRsf.npled...eDdvqikkRsaslnskpsslR 350 +++ Rl+ G ++qE ++ vEvmi + EnL R ++ +L+el k+ l +e s pl + d q s sl+s FUN_001116-T1 770 IIQTSFKRLSTQSQQHGCVQQEAHMASGVEVMICHAENLSRHLERAREDLNELrvKERLEADETSTpSPLANgstSYDSQSGLTSQSLQSDKH--H 863 ****************************************************84456677777776244543111456677777778875433..2 PP MRVI1 351 RvsiAslPr..niGnsgsvsgi...esndrlsrrssswr........lLeskk..sehrpslerfistyswsdaEeekqevkakdeeEayn..eEa 429 R+ A n + ++++ e + ++ rs +r Les s ++ t s ++ e + e +dee + n eE+ FUN_001116-T1 864 RIDPAKRNSllNFVTAFHTTSMrakEALRSFRSRSGMGRqraasavpRLESSVplSADENTSTWQPRTNSEICFTETRGEQAERDEEGTDNfeEEI 959 333332222334444433444411166667777777777999998776666532244444445566788888999999999888888888787888 PP MRVI1 430 vektrkpslsekkeetskwdv 450 e t + ++s+ +et++ d FUN_001116-T1 960 SEDTAQGKVSDGTDETTENDS 980 899999888888777776663 PP >> DUF5945 Family of unknown function (DUF5945) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 2.9 1.6e-05 0.21 1 129 [. 103 232 .. 103 233 .. 0.78 2 ? -3.6 0.1 1.6 2.1e+04 90 117 .. 252 283 .. 248 288 .. 0.62 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.6e-05 DUF5945 1 mskdwqydeplddkktassseera....kiaalfgkkeekaieevdyvaafeqeqkkakekdvqal.lkeevkqavpkkvtitkdykkhladviaq 91 m ++w ld t+s+ e+ + ++a+ f++k+eka+ ++d +aa+++ + + k+v l++++ +kv+ + k+++a+ a FUN_001116-T1 103 MNNSWMSSVSLDSTSTSSTFEKYSltalQMASEFKEKKEKALRQIDELAALDRSVEVKDRKEVLIRqLAQDLD-NFAEKVS-SLSIKRKVAEKRAV 196 677899999999988888777643222367788*******************999988888886641344444.4444454.34589999998775 PP DUF5945 92 nkkdiaacqkqieelhqlidekkkqnkklqaisvaide 129 k ++a+qk ee + l +e+ + +kl ++s+ de FUN_001116-T1 197 --KLLTASQKLKEENKLLFEERSRAYQKLGTMSLCNDE 232 ..678888*************************99988 PP == domain 2 score: -3.6 bits; conditional E-value: 1.6 DUF5945 90 aqnkkdiaacqkqi....eelhqlidekkkqn 117 aq+++++a ++q+ e+l ++ dek+ FUN_001116-T1 252 AQQREELAFLEQQLskvtEDLFKIRDEKESLS 283 56666666555443222278888889987655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1067 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2628 (0.102877); expected 510.9 (0.02) Passed bias filter: 795 (0.0311216); expected 510.9 (0.02) Passed Vit filter: 94 (0.00367978); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.55u 0.39s 00:00:00.94 Elapsed: 00:00:00.44 # Mc/sec: 9775.78 // Query: FUN_001116-T2 [L=1382] Description: FUN_001116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-27 96.4 30.9 2.8e-27 96.4 30.9 4.8 4 KASH_CCD Coiled-coil region of CCDC155 or KASH 1.7e-21 77.0 21.3 1.7e-21 77.0 21.3 3.3 3 MRVI1 MRVI1 protein 1.2e-11 45.4 0.0 3e-11 44.1 0.0 1.8 1 EF-hand_9 EF-hand domain ------ inclusion threshold ------ 0.012 16.5 9.3 0.012 16.5 9.3 9.1 9 ZapB Cell division protein ZapB Domain annotation for each model (and alignments): >> KASH_CCD Coiled-coil region of CCDC155 or KASH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.4 30.9 4.4e-31 2.8e-27 4 188 .. 157 338 .. 155 341 .. 0.96 2 ? -0.8 18.2 0.28 1.8e+03 63 177 .. 483 587 .. 438 594 .. 0.75 3 ? 0.8 16.3 0.092 5.9e+02 60 132 .. 592 664 .. 571 678 .. 0.87 4 ? -0.9 2.6 0.3 1.9e+03 120 167 .. 1036 1083 .. 1010 1100 .. 0.69 Alignments for each domain: == domain 1 score: 96.4 bits; conditional E-value: 4.4e-31 KASH_CCD 4 adlistvedLqlnNkkLaeensklqkavetaeetnakLteEieeLkkklkstQqalqkakllkeEledlktlvksleEraaslqaqnkqlekenqs 99 ++list+e+LqlnNk+L e+ +q+++e +eetn++Lt+E+e+L+k+l+s Q k k ++E+++l+++v ++ E+++slq++ qleke FUN_001116-T2 157 SELISTIESLQLNNKRLMEQHNAIQAQMESTEETNNQLTAEVEALRKQLRSYQLMIDKSKEREKENAELRQTVADTLEEKQSLQTKITQLEKECTL 252 69********************************************************************************************** PP KASH_CCD 100 LeakiesLqeeneklaaerdllkkklkeLleekaeLkkqlyeleellasreelleektkqieeLkstveEyssvteeLraeisrLeeql 188 e++++ + +++ + e +ll+ + + L++ ae k+ l+e+ ++++ ++ + + ++ ++ + s +e L++e+srLe+++ FUN_001116-T2 253 YESNLNRIGDKLLEAQGEVELLEDERRRLVNDLAEQKQYCSDLQEIQGVKNDMIAKENSTNSSM---IVGLASENETLKMEKSRLENRI 338 ******************************************************9999988776...66778999***********986 PP == domain 2 score: -0.8 bits; conditional E-value: 0.28 KASH_CCD 63 kllkeEledlktlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaaerdllkkklkeLleekaeLkkqlyeleellasreelleektk 158 + l+ + + + E+ sl ++k +ek L ++L+een+ l er+ +kl + ++e+ l+ele+ l e++ + + FUN_001116-T2 483 RQLA-------QDLDNFAEKVSSLSIKRKVAEKRAVKLLTASQKLKEENKLLFEERSRAYQKLGTMSLCNDEMSARLFELEKRL---EQERKAGAQ 568 3333.......3445667888899999999***********************************************9998744...333344556 PP KASH_CCD 159 qieeLkstveEyssvteeL 177 q eeL++ + +s+vte+L FUN_001116-T2 569 QREELAFLEQQLSKVTEDL 587 7788888888888888866 PP == domain 3 score: 0.8 bits; conditional E-value: 0.092 KASH_CCD 60 qkakllkeEledlktlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaaerdllkkklkeLleek 132 ++++l+ le+ k+l +sle++ s+ + le ++ L ++i++L+ e+ k ++ ++ k+++ L e++ FUN_001116-T2 592 DEKESLSRSLENEKRLSSSLEDELVSIRKSQDELESQQTILLVRIKELESELLKTSSQLNVEKRRTSSLEESI 664 4578999************************************************************998876 PP == domain 4 score: -0.9 bits; conditional E-value: 0.3 KASH_CCD 120 llkkklkeLleekaeLkkqlyeleellasreelleektkq..ieeLkstv 167 ++++++++ +e++ + k+l+++ +ll + e+l + +q +Lks+v FUN_001116-T2 1036 EVQSRSRDVAESN--MSKELQSMSNLLKDFEQLCITRDMQdmLSSLKSQV 1083 5677777777777..88888888888888888877665542234444444 PP >> MRVI1 MRVI1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 5.0 0.22 1.4e+03 108 226 .. 105 259 .. 76 296 .. 0.76 2 ? -12.1 11.8 4 2.6e+04 96 101 .. 541 546 .. 361 667 .. 0.61 3 ! 77.0 21.3 2.7e-25 1.7e-21 73 450 .. 896 1295 .. 878 1353 .. 0.76 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.22 MRVI1 108 askaaekqlkspafkdlqlqvs...................................llreknlvgleakelsetveeekkesaagedvvsslpdv 168 +s ++ + +sp +++++s + ++ +l + ++ e+ ++++ + + + +++++++ ++ FUN_001116-T2 105 PSPVTVNCMESPESRSYNIPKSiignhvtstpnvssesveglggespdrdwpselisTIESLQLNNKRLMEQHNAIQAQMESTEETNNQLTAEVEA 200 55555555555555555555555555555556666666666666666666666665567777888889999999999999999999999999999* PP MRVI1 169 lvkkvrvrksentsatekevEaeFlrLsLafk.cDsftLEkRvkleERsRdLaEEnlkk 226 l k++r + ++e+e E+ lr +a + L ++ + E++ L E nl++ FUN_001116-T2 201 LRKQLRSYQLMIDKSKEREKENAELRQTVADTlEEKQSLQTKITQLEKECTLYESNLNR 259 *********99999*********999999965256789*****************9986 PP == domain 2 score: -12.1 bits; conditional E-value: 4 MRVI1 96 kelcek 101 ++lc+ FUN_001116-T2 541 MSLCND 546 333333 PP == domain 3 score: 77.0 bits; conditional E-value: 2.7e-25 MRVI1 73 estvtssdsrsellrmasgDsdckelcekeeekrsaskaaekqlkspafkdlqlqvsllreknlvgleakelsetveeekk....esaagedvv 162 estv + + r sg s++ +++ e++s ++ + +++ks +++ ++l l +ek++ +l k+ls + ++ sa+ge+ FUN_001116-T2 896 ESTVENLNGDQRQRRRKSGLSGSLLTADTATETKSDANESASKSKSETIDSTKLCPVLEKEKKATNLWRKKLSVAFKTPEEfepySSATGEALE 989 555555555566666667777777777888899999999999999999*****99999999999999999998877665555566888888888 PP MRVI1 163 sslpdvlvkkvrvrksentsatekevEaeFlrLsLafkcDsftLEkRvkleERsRdLaEEnlkkEltnflkllesltsLcEddnqarEiikkLe 256 s+ v v +r + +eke+E +F L Laf++D tL++R++ + RsRd+aE n+ kEl+ + +ll+ +Lc + ++++ L+ FUN_001116-T2 990 DSVGSNFVDGVSLRVR--PAPNEKEIEKQFRTLVLAFHTDQDTLNRRLEVQSRSRDVAESNMSKELQSMSNLLKDFEQLCIT-RDMQDMLSSLK 1080 8888888887777643..3459**********************************************************99.899******** PP MRVI1 257 kdiavLsrlaaRlasRAEmlGAirqEsRvskAvEvmiqyvEnLkRmYakeHAELeel..kkvllqneRsf.npled...eDdvqikkRsaslns 344 +++ +++ Rl+ G ++qE ++ vEvmi + EnL R ++ +L+el k+ l +e s pl + d q s sl+s FUN_001116-T2 1081 SQVEIIQTSFKRLSTQSQQHGCVQQEAHMASGVEVMICHAENLSRHLERAREDLNELrvKERLEADETSTpSPLANgstSYDSQSGLTSQSLQS 1174 ********************************************************84456677777776244543111446677777778875 PP MRVI1 345 kpsslRRvsiAslPr..niGnsgsvsgi...esndrlsrrssswr........lLeskk..sehrpslerfistyswsdaEeekqevkakdeeE 423 R+ A n + ++++ e + ++ rs +r Les s ++ t s ++ e + e +dee FUN_001116-T2 1175 DKH--HRIDPAKRNSllNFVTAFHTTSMrakEALRSFRSRSGMGRqraasavpRLESSVplSADENTSTWQPRTNSEICFTETRGEQAERDEEG 1266 433..23333322223344344334444111666677777777779999987766655322444444455667888889999999998888888 PP MRVI1 424 ayn..eEavektrkpslsekkeetskwdv 450 + n eE+ e t + ++s+ +et++ d FUN_001116-T2 1267 TDNfeEEISEDTAQGKVSDGTDETTENDS 1295 88787888899998888887777776663 PP >> EF-hand_9 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.1 0.0 4.7e-15 3e-11 2 66 .] 22 88 .. 21 88 .. 0.95 Alignments for each domain: == domain 1 score: 44.1 bits; conditional E-value: 4.7e-15 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaaqdpqel..eleelarelDPdgedatveldtFlrVmrdwi 66 s+F +cDt+ G+V vskli+yLr ++++e +l++l DPdg++ +++l tF ++ wi FUN_001116-T2 22 SLFYACDTEHLGRVSVSKLIDYLRNAISNGTEEFagNLDDLSLIWDPDGRNMEIDLATFQEGIKEWI 88 78**********************9999999999999***********************9999997 PP >> ZapB Cell division protein ZapB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.5 9.3 1.9e-06 0.012 15 64 .. 158 207 .. 157 214 .. 0.95 2 ? 4.1 7.0 0.014 92 15 65 .. 210 260 .. 206 266 .. 0.83 3 ? -2.7 6.9 2 1.2e+04 45 62 .. 302 338 .. 254 341 .. 0.59 4 ? 3.4 3.5 0.025 1.6e+02 23 55 .. 320 358 .. 315 388 .. 0.64 5 ? -0.8 1.0 0.48 3.1e+03 23 65 .. 445 499 .. 441 502 .. 0.72 6 ? 0.4 2.5 0.21 1.4e+03 31 59 .. 507 535 .. 481 545 .. 0.54 7 ? -10.1 15.4 4 2.6e+04 18 56 .. 515 564 .. 505 603 .. 0.50 8 ? -6.1 10.1 4 2.6e+04 19 64 .. 593 638 .. 570 651 .. 0.56 9 ? -2.5 1.4 1.6 1e+04 55 55 .. 1106 1106 .. 1070 1145 .. 0.48 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 1.9e-06 ZapB 15 aavdtielLkmeveeLkekneelaeeaeeleeenqqlkeernawqerles 64 +++ tie+L+ +++L+e++++ + + e ee n+ql++e +a+++ l+s FUN_001116-T2 158 ELISTIESLQLNNKRLMEQHNAIQAQMESTEETNNQLTAEVEALRKQLRS 207 6899*****************************************99986 PP == domain 2 score: 4.1 bits; conditional E-value: 0.014 ZapB 15 aavdtielLkmeveeLkekneelaeeaeeleeenqqlkeernawqerlesL 65 +d+ ++ +e++eL+++++ ee + l++++ ql++e ++ l+ + FUN_001116-T2 210 LMIDKSKEREKENAELRQTVADTLEEKQSLQTKITQLEKECTLYESNLNRI 260 56777777789***************************9998888888765 PP == domain 3 score: -2.7 bits; conditional E-value: 2 ZapB 45 e...................eenqqlkeernawqerl 62 + en+ lk e++ +++r+ FUN_001116-T2 302 KndmiakenstnssmivglaSENETLKMEKSRLENRI 338 0444444444444455555588888888888888877 PP == domain 4 score: 3.4 bits; conditional E-value: 0.025 ZapB 23 LkmeveeLkekneelaeeaeele......eenqqlkeer 55 L e+e Lk++++ l++++ le +++ +l+ er FUN_001116-T2 320 LASENETLKMEKSRLENRILDLEdnvlrlQRIDKLSPER 358 677888888888888888888886666664444444333 PP == domain 5 score: -0.8 bits; conditional E-value: 0.48 ZapB 23 LkmeveeLkekneelaeeaeele.............eenqqlkeernawqerlesL 65 L+m +e kek+e+ +++el + ql ++ ++ e+++sL FUN_001116-T2 445 LQM-ASEFKEKKEKALRQIDELAaldrsvevkdrkeVLIRQLAQDLDNFAEKVSSL 499 555.3567777777777788888777777777776666778888888888888776 PP == domain 6 score: 0.4 bits; conditional E-value: 0.21 ZapB 31 kekneelaeeaeeleeenqqlkeernawq 59 +++ +l ++l+een+ l eer+ FUN_001116-T2 507 EKRAVKLLTASQKLKEENKLLFEERSRAY 535 33334444445555555555555555544 PP == domain 7 score: -10.1 bits; conditional E-value: 4 ZapB 18 dtielLkmeveeLkekneelaeeaeele...........eenqqlkeern 56 ++Lk+e++ L e+ + +++ ++ e ++l++er+ FUN_001116-T2 515 TASQKLKEENKLLFEERSRAYQKLGTMSlcndemsarlfELEKRLEQERK 564 55555555555555555544444444444444444444422222222222 PP == domain 8 score: -6.1 bits; conditional E-value: 4 ZapB 19 tielLkmeveeLkekneelaeeaeeleeenqqlkeernawqerles 64 + e+L + +e +k+ ++l++e+ ++++ l+ ++ + r+++ FUN_001116-T2 593 EKESLSRSLENEKRLSSSLEDELVSIRKSQDELESQQTILLVRIKE 638 3344555555555555555555555555555555555555555554 PP == domain 9 score: -2.5 bits; conditional E-value: 1.6 ZapB 55 r 55 FUN_001116-T2 1106 E 1106 0 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1382 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2565 (0.100411); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 139 (0.00544138); expected 25.5 (0.001) Passed Fwd filter: 50 (0.00195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.80u 0.42s 00:00:01.22 Elapsed: 00:00:00.45 # Mc/sec: 12408.84 // Query: FUN_001116-T3 [L=1086] Description: FUN_001116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-22 77.9 21.2 9.5e-22 77.9 21.2 2.5 2 MRVI1 MRVI1 protein ------ inclusion threshold ------ 0.7 10.9 6.7 0.21 12.6 2.9 2.2 2 DUF5945 Family of unknown function (DUF5945) Domain annotation for each model (and alignments): >> MRVI1 MRVI1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -12.0 12.2 2 2.6e+04 96 101 .. 245 250 .. 69 372 .. 0.61 2 ! 77.9 21.2 7.5e-26 9.5e-22 73 450 .. 600 999 .. 581 1058 .. 0.76 Alignments for each domain: == domain 1 score: -12.0 bits; conditional E-value: 2 MRVI1 96 kelcek 101 ++lc+ FUN_001116-T3 245 MSLCND 250 333333 PP == domain 2 score: 77.9 bits; conditional E-value: 7.5e-26 MRVI1 73 estvtssdsrsellrmasgDsdckelcekeeekrsaskaaekqlkspafkdlqlqvsllreknlvgleakelsetveeekk....esaagedvvss 164 estv + + r sg s++ +++ e++s ++ + +++ks +++ ++l l +ek++ +l k+ls + ++ sa+ge+ s FUN_001116-T3 600 ESTVENLNGDQRQRRRKSGLSGSLLTADTATETKSDANESASKSKSETIDSTKLCPVLEKEKKATNLWRKKLSVAFKTPEEfepySSATGEALEDS 695 55555555556666667777777777788889999999999999999*******999999999999999999887766555556688888888888 PP MRVI1 165 lpdvlvkkvrvrksentsatekevEaeFlrLsLafkcDsftLEkRvkleERsRdLaEEnlkkEltnflkllesltsLcEddnqarEiikkLekdia 260 + v v +r + +eke+E +F L Laf++D tL++R++ + RsRd+aE n+ kEl+ + +ll+ +Lc + ++++ L++++ FUN_001116-T3 696 VGSNFVDGVSLRVR--PAPNEKEIEKQFRTLVLAFHTDQDTLNRRLEVQSRSRDVAESNMSKELQSMSNLLKDFEQLCIT-RDMQDMLSSLKSQVE 788 88888887777643..3459**********************************************************99.899************ PP MRVI1 261 vLsrlaaRlasRAEmlGAirqEsRvskAvEvmiqyvEnLkRmYakeHAELeel..kkvllqneRsf.npled...eDdvqikkRsaslnskpsslR 350 +++ Rl+ G ++qE ++ vEvmi + EnL R ++ +L+el k+ l +e s pl + d q s sl+s FUN_001116-T3 789 IIQTSFKRLSTQSQQHGCVQQEAHMASGVEVMICHAENLSRHLERAREDLNELrvKERLEADETSTpSPLANgstSYDSQSGLTSQSLQSDKH--H 882 ****************************************************84456677777776244543111456677777778875433..2 PP MRVI1 351 RvsiAslPr..niGnsgsvsgi...esndrlsrrssswr........lLeskk..sehrpslerfistyswsdaEeekqevkakdeeEayn..eEa 429 R+ A n + ++++ e + ++ rs +r Les s ++ t s ++ e + e +dee + n eE+ FUN_001116-T3 883 RIDPAKRNSllNFVTAFHTTSMrakEALRSFRSRSGMGRqraasavpRLESSVplSADENTSTWQPRTNSEICFTETRGEQAERDEEGTDNfeEEI 978 333332222334444433444411166667777777777999998776666532244444445566788888999999999888888888787888 PP MRVI1 430 vektrkpslsekkeetskwdv 450 e t + ++s+ +et++ d FUN_001116-T3 979 SEDTAQGKVSDGTDETTENDS 999 899999888888777776663 PP >> DUF5945 Family of unknown function (DUF5945) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 2.9 1.6e-05 0.21 1 129 [. 122 251 .. 122 252 .. 0.78 2 ? -3.6 0.1 1.7 2.1e+04 90 117 .. 271 302 .. 267 307 .. 0.62 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.6e-05 DUF5945 1 mskdwqydeplddkktassseera....kiaalfgkkeekaieevdyvaafeqeqkkakekdvqal.lkeevkqavpkkvtitkdykkhladviaq 91 m ++w ld t+s+ e+ + ++a+ f++k+eka+ ++d +aa+++ + + k+v l++++ +kv+ + k+++a+ a FUN_001116-T3 122 MNNSWMSSVSLDSTSTSSTFEKYSltalQMASEFKEKKEKALRQIDELAALDRSVEVKDRKEVLIRqLAQDLD-NFAEKVS-SLSIKRKVAEKRAV 215 677899999999988888777643222367788*******************999988888886641344444.4444454.34589999998775 PP DUF5945 92 nkkdiaacqkqieelhqlidekkkqnkklqaisvaide 129 k ++a+qk ee + l +e+ + +kl ++s+ de FUN_001116-T3 216 --KLLTASQKLKEENKLLFEERSRAYQKLGTMSLCNDE 251 ..678888*************************99988 PP == domain 2 score: -3.6 bits; conditional E-value: 1.7 DUF5945 90 aqnkkdiaacqkqi....eelhqlidekkkqn 117 aq+++++a ++q+ e+l ++ dek+ FUN_001116-T3 271 AQQREELAFLEQQLskvtEDLFKIRDEKESLS 302 56666666555443222278888889987655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1086 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1957 (0.0766099); expected 510.9 (0.02) Passed bias filter: 520 (0.0203562); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.49u 0.41s 00:00:00.89 Elapsed: 00:00:00.42 # Mc/sec: 10302.42 // Query: FUN_001116-T4 [L=1209] Description: FUN_001116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-21 77.0 21.6 1.7e-21 77.0 21.6 3.0 4 MRVI1 MRVI1 protein 7.1e-18 65.8 29.9 7.1e-18 65.8 29.9 4.9 4 KASH_CCD Coiled-coil region of CCDC155 or KASH ------ inclusion threshold ------ 4.2 7.3 7.0 1.1 9.2 2.8 2.3 2 Rota_NSP4 Rotavirus non structural protein Domain annotation for each model (and alignments): >> MRVI1 MRVI1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 1.7 0.46 3.9e+03 152 226 .. 11 86 .. 2 122 .. 0.68 2 ? -5.2 4.3 1.6 1.4e+04 95 244 .. 206 357 .. 113 379 .. 0.48 3 ? -5.7 4.8 2.3 2e+04 115 167 .. 396 447 .. 314 494 .. 0.57 4 ! 77.0 21.6 2e-25 1.7e-21 73 450 .. 723 1122 .. 705 1181 .. 0.76 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 0.46 MRVI1 152 kkesaagedvvsslpdvlvkkvrvrksentsatekevEaeFlrLsLafk.cDsftLEkRvkleERsRdLaEEnlkk 226 + + +++++++ ++l k++r + ++e+e E+ lr +a + L ++ + E++ L E nl++ FUN_001116-T4 11 MESTEETNNQLTAEVEALRKQLRSYQLMIDKSKEREKENAELRQTVADTlEEKQSLQTKITQLEKECTLYESNLNR 86 4445555566666666777777777777777777777777777777754145667788888888888888877764 PP == domain 2 score: -5.2 bits; conditional E-value: 1.6 MRVI1 95 ckelcekeeekrsaskaaekqlkspafkdlqlqvs...llreknl..vgleakelsetveeekkesaagedvvsslpdvlvkk.vrvrksentsat 184 e e e k +s + +q d++ q+ +++ + v+l+ s t e+ + +++ + ++ kk +r+ ++ +a FUN_001116-T4 206 ELEAQESHETKDLPSPMVGSQFDLNDSLDVDAQNMalsGMNNSWMssVSLDSTSTSSTFEKY------SLTALQMASEFKEKKeKALRQIDELAAL 295 33344444444444444444433332222222222111222222200122222222222222......2222222222222110223333333332 PP MRVI1 185 ekevE....aeFlrLsLafkcDsftLEkRvkleERsRdLaEEnlkkEltnflkllesltsLcEd 244 +++vE e l La D f ++v +R +aE + k lt +kl e L+E+ FUN_001116-T4 296 DRSVEvkdrKEVLIRQLAQDLDNFA--EKVSSLSIKRKVAEKRAVKLLTASQKLKEENKLLFEE 357 2222211111222223444444443..3444445555555555555555555555555555555 PP == domain 3 score: -5.7 bits; conditional E-value: 2.3 MRVI1 115 qlkspafkdlqlqvs....llreknlvgleakelsetveeekkesaagedvvsslpd 167 q + af + + ++++ ++ e + ls+++e+ek+ s + ed++ s+ + FUN_001116-T4 396 QREELAFLE-----QqlskVTEDLFKIRDEKESLSRSLENEKRLSSSLEDELVSIRK 447 122222222.....2222255555555566666777777777766666666666653 PP == domain 4 score: 77.0 bits; conditional E-value: 2e-25 MRVI1 73 estvtssdsrsellrmasgDsdckelcekeeekrsaskaaekqlkspafkdlqlqvsllreknlvgleakelsetveeekk....esaagedvv 162 estv + + r sg s++ +++ e++s ++ + +++ks +++ ++l l +ek++ +l k+ls + ++ sa+ge+ FUN_001116-T4 723 ESTVENLNGDQRQRRRKSGLSGSLLTADTATETKSDANESASKSKSETIDSTKLCPVLEKEKKATNLWRKKLSVAFKTPEEfepySSATGEALE 816 555555555566666667777777777888899999999999999999******9999999999999999998877665555566888888888 PP MRVI1 163 sslpdvlvkkvrvrksentsatekevEaeFlrLsLafkcDsftLEkRvkleERsRdLaEEnlkkEltnflkllesltsLcEddnqarEiikkLe 256 s+ v v +r + +eke+E +F L Laf++D tL++R++ + RsRd+aE n+ kEl+ + +ll+ +Lc + ++++ L+ FUN_001116-T4 817 DSVGSNFVDGVSLRVR--PAPNEKEIEKQFRTLVLAFHTDQDTLNRRLEVQSRSRDVAESNMSKELQSMSNLLKDFEQLCIT-RDMQDMLSSLK 907 8888888887777643..3459**********************************************************99.899******** PP MRVI1 257 kdiavLsrlaaRlasRAEmlGAirqEsRvskAvEvmiqyvEnLkRmYakeHAELeel..kkvllqneRsf.npled...eDdvqikkRsaslns 344 +++ +++ Rl+ G ++qE ++ vEvmi + EnL R ++ +L+el k+ l +e s pl + d q s sl+s FUN_001116-T4 908 SQVEIIQTSFKRLSTQSQQHGCVQQEAHMASGVEVMICHAENLSRHLERAREDLNELrvKERLEADETSTpSPLANgstSYDSQSGLTSQSLQS 1001 ********************************************************84456677777776244543111446677777778875 PP MRVI1 345 kpsslRRvsiAslPr..niGnsgsvsgi...esndrlsrrssswr........lLeskk..sehrpslerfistyswsdaEeekqevkakdeeE 423 R+ A n + ++++ e + ++ rs +r Les s ++ t s ++ e + e +dee FUN_001116-T4 1002 DKH--HRIDPAKRNSllNFVTAFHTTSMrakEALRSFRSRSGMGRqraasavpRLESSVplSADENTSTWQPRTNSEICFTETRGEQAERDEEG 1093 433..23333322223344444334444111666677777777779999987766665322444444455667888889999999998888888 PP MRVI1 424 ayn..eEavektrkpslsekkeetskwdv 450 + n eE+ e t + ++s+ +et++ d FUN_001116-T4 1094 TDNfeEEISEDTAQGKVSDGTDETTENDS 1122 88787888899998888887777776663 PP >> KASH_CCD Coiled-coil region of CCDC155 or KASH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.8 29.9 8.3e-22 7.1e-18 22 188 .. 2 165 .. 1 168 [. 0.96 2 ? -1.2 20.7 0.27 2.3e+03 63 187 .. 310 427 .. 264 430 .. 0.74 3 ? -0.8 19.6 0.22 1.8e+03 40 132 .. 395 491 .. 386 509 .. 0.82 4 ? -1.1 3.0 0.25 2.2e+03 120 167 .. 863 910 .. 837 927 .. 0.69 Alignments for each domain: == domain 1 score: 65.8 bits; conditional E-value: 8.3e-22 KASH_CCD 22 eensklqkavetaeetnakLteEieeLkkklkstQqalqkakllkeEledlktlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaae 117 e+ +q+++e +eetn++Lt+E+e+L+k+l+s Q k k ++E+++l+++v ++ E+++slq++ qleke e++++ + +++ + e FUN_001116-T4 2 EQHNAIQAQMESTEETNNQLTAEVEALRKQLRSYQLMIDKSKEREKENAELRQTVADTLEEKQSLQTKITQLEKECTLYESNLNRIGDKLLEAQGE 97 89999******************************************************************************************* PP KASH_CCD 118 rdllkkklkeLleekaeLkkqlyeleellasreelleektkqieeLkstveEyssvteeLraeisrLeeql 188 +ll+ + + L++ ae k+ l+e+ ++++ ++ + + ++ ++ + s +e L++e+srLe+++ FUN_001116-T4 98 VELLEDERRRLVNDLAEQKQYCSDLQEIQGVKNDMIAKENSTNSSM---IVGLASENETLKMEKSRLENRI 165 ************************************9999988776...66778999***********986 PP == domain 2 score: -1.2 bits; conditional E-value: 0.27 KASH_CCD 63 kllkeEledlktlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaaerdllkkklkeLleekaeLkkqlyeleellasreelleektk 158 + l+ + + + E+ sl ++k +ek L ++L+een+ l er+ +kl + ++e+ l+ele+ l e++ + + FUN_001116-T4 310 RQLA-------QDLDNFAEKVSSLSIKRKVAEKRAVKLLTASQKLKEENKLLFEERSRAYQKLGTMSLCNDEMSARLFELEKRL---EQERKAGAQ 395 3333.......344566788889999999*************************************************999754...333445566 PP KASH_CCD 159 qieeLkstveEyssvte...eLraeisrLeeq 187 q eeL++ + +s+vte ++r e++ L FUN_001116-T4 396 QREELAFLEQQLSKVTEdlfKIRDEKESLSRS 427 77999999999999999333346777776655 PP == domain 3 score: -0.8 bits; conditional E-value: 0.22 KASH_CCD 40 kLteEieeLkkklkstQqal....qkakllkeEledlktlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaaerdllkkklkeLlee 131 + eE+ L ++l l ++++l+ le+ k+l +sle++ s+ + le ++ L ++i++L+ e+ k ++ ++ k+++ L e+ FUN_001116-T4 395 QQREELAFLEQQLSKVTEDLfkirDEKESLSRSLENEKRLSSSLEDELVSIRKSQDELESQQTILLVRIKELESELLKTSSQLNVEKRRTSSLEES 490 55677777777775544443111145789**************************************************************99887 PP KASH_CCD 132 k 132 + FUN_001116-T4 491 I 491 6 PP == domain 4 score: -1.1 bits; conditional E-value: 0.25 KASH_CCD 120 llkkklkeLleekaeLkkqlyeleellasreelleektkq..ieeLkstv 167 ++++++++ +e++ + k+l+++ +ll + e+l + +q +Lks+v FUN_001116-T4 863 EVQSRSRDVAESN--MSKELQSMSNLLKDFEQLCITRDMQdmLSSLKSQV 910 5677777777777..88888888888888888877665542234444444 PP >> Rota_NSP4 Rotavirus non structural protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 2.8 0.00013 1.1 87 139 .. 9 65 .. 3 91 .. 0.83 2 ? -3.5 0.1 1.1 9e+03 140 150 .. 872 882 .. 848 919 .. 0.51 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00013 Rota_NSP4 87 eqltdkdeiekqidrvvkelrrqle....mieklttreieqvellkriydklivrtd 139 q+ + +e+++q+ v lr+ql mi+k re e+ el + + d l +++ FUN_001116-T4 9 AQMESTEETNNQLTAEVEALRKQLRsyqlMIDKSKEREKENAELRQTVADTLEEKQS 65 677888999****99999999999656669******************999976655 PP == domain 2 score: -3.5 bits; conditional E-value: 1.1 Rota_NSP4 140 seidmskeinq 150 +e +mske++ FUN_001116-T4 872 AESNMSKELQS 882 34444444321 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1209 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2851 (0.111607); expected 510.9 (0.02) Passed bias filter: 730 (0.028577); expected 510.9 (0.02) Passed Vit filter: 134 (0.00524564); expected 25.5 (0.001) Passed Fwd filter: 44 (0.00172245); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.75u 0.44s 00:00:01.19 Elapsed: 00:00:00.45 # Mc/sec: 10765.62 // Query: FUN_001116-T5 [L=1078] Description: FUN_001116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-22 77.9 21.2 9.4e-22 77.9 21.2 2.5 3 MRVI1 MRVI1 protein ------ inclusion threshold ------ 0.68 10.9 6.7 0.21 12.6 2.9 2.2 2 DUF5945 Family of unknown function (DUF5945) Domain annotation for each model (and alignments): >> MRVI1 MRVI1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.9 3.8 0.93 1.2e+04 115 166 .. 127 145 .. 41 251 .. 0.42 2 ? -4.0 3.0 0.5 6.3e+03 118 194 .. 268 341 .. 225 363 .. 0.51 3 ! 77.9 21.2 7.3e-26 9.4e-22 73 450 .. 592 991 .. 573 1050 .. 0.76 Alignments for each domain: == domain 1 score: -4.9 bits; conditional E-value: 0.93 MRVI1 115 qlkspafkdlqlqvsllreknlvgleakelsetveeekkesaagedvvsslp 166 +++s++f+ ++l ++ + + FUN_001116-T5 127 TSTSSTFEKYSLT---------------------------------ALQMAS 145 2222222222222.................................222222 PP == domain 2 score: -4.0 bits; conditional E-value: 0.5 MRVI1 118 spafkdlqlqvs....llreknlvgleakelsetveeekkesaagedvvsslpdvlvkkvrvrksentsatekevEaeFlr 194 af + + ++++ ++ e + ls+++e+ek+ s + ed++ s+ + +++ +++ ke E+e l+ FUN_001116-T5 268 ELAFLE-----QqlskVTEDLFKIRDEKESLSRSLENEKRLSSSLEDELVSIRKS-QDELESQQTI-LLVRIKELESELLK 341 222222.....22222555555566666677777777777777777766666532.2333333322.23345555555555 PP == domain 3 score: 77.9 bits; conditional E-value: 7.3e-26 MRVI1 73 estvtssdsrsellrmasgDsdckelcekeeekrsaskaaekqlkspafkdlqlqvsllreknlvgleakelsetveeekk....esaagedvvss 164 estv + + r sg s++ +++ e++s ++ + +++ks +++ ++l l +ek++ +l k+ls + ++ sa+ge+ s FUN_001116-T5 592 ESTVENLNGDQRQRRRKSGLSGSLLTADTATETKSDANESASKSKSETIDSTKLCPVLEKEKKATNLWRKKLSVAFKTPEEfepySSATGEALEDS 687 55555555556666667777777777788889999999999999999*******999999999999999999887766555556688888888888 PP MRVI1 165 lpdvlvkkvrvrksentsatekevEaeFlrLsLafkcDsftLEkRvkleERsRdLaEEnlkkEltnflkllesltsLcEddnqarEiikkLekdia 260 + v v +r + +eke+E +F L Laf++D tL++R++ + RsRd+aE n+ kEl+ + +ll+ +Lc + ++++ L++++ FUN_001116-T5 688 VGSNFVDGVSLRVR--PAPNEKEIEKQFRTLVLAFHTDQDTLNRRLEVQSRSRDVAESNMSKELQSMSNLLKDFEQLCIT-RDMQDMLSSLKSQVE 780 88888887777643..3459**********************************************************99.899************ PP MRVI1 261 vLsrlaaRlasRAEmlGAirqEsRvskAvEvmiqyvEnLkRmYakeHAELeel..kkvllqneRsf.npled...eDdvqikkRsaslnskpsslR 350 +++ Rl+ G ++qE ++ vEvmi + EnL R ++ +L+el k+ l +e s pl + d q s sl+s FUN_001116-T5 781 IIQTSFKRLSTQSQQHGCVQQEAHMASGVEVMICHAENLSRHLERAREDLNELrvKERLEADETSTpSPLANgstSYDSQSGLTSQSLQSDKH--H 874 ****************************************************84456677777776244543111456677777778875433..2 PP MRVI1 351 RvsiAslPr..niGnsgsvsgi...esndrlsrrssswr........lLeskk..sehrpslerfistyswsdaEeekqevkakdeeEayn..eEa 429 R+ A n + ++++ e + ++ rs +r Les s ++ t s ++ e + e +dee + n eE+ FUN_001116-T5 875 RIDPAKRNSllNFVTAFHTTSMrakEALRSFRSRSGMGRqraasavpRLESSVplSADENTSTWQPRTNSEICFTETRGEQAERDEEGTDNfeEEI 970 333332222334444433444411166667777777777999998776666532244444445566788888999999999888888888787888 PP MRVI1 430 vektrkpslsekkeetskwdv 450 e t + ++s+ +et++ d FUN_001116-T5 971 SEDTAQGKVSDGTDETTENDS 991 899999888888777776663 PP >> DUF5945 Family of unknown function (DUF5945) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 2.9 1.6e-05 0.21 1 129 [. 114 243 .. 114 244 .. 0.78 2 ? -3.6 0.1 1.6 2.1e+04 90 117 .. 263 294 .. 259 299 .. 0.62 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.6e-05 DUF5945 1 mskdwqydeplddkktassseera....kiaalfgkkeekaieevdyvaafeqeqkkakekdvqal.lkeevkqavpkkvtitkdykkhladviaq 91 m ++w ld t+s+ e+ + ++a+ f++k+eka+ ++d +aa+++ + + k+v l++++ +kv+ + k+++a+ a FUN_001116-T5 114 MNNSWMSSVSLDSTSTSSTFEKYSltalQMASEFKEKKEKALRQIDELAALDRSVEVKDRKEVLIRqLAQDLD-NFAEKVS-SLSIKRKVAEKRAV 207 677899999999988888777643222367788*******************999988888886641344444.4444454.34589999998775 PP DUF5945 92 nkkdiaacqkqieelhqlidekkkqnkklqaisvaide 129 k ++a+qk ee + l +e+ + +kl ++s+ de FUN_001116-T5 208 --KLLTASQKLKEENKLLFEERSRAYQKLGTMSLCNDE 243 ..678888*************************99988 PP == domain 2 score: -3.6 bits; conditional E-value: 1.6 DUF5945 90 aqnkkdiaacqkqi....eelhqlidekkkqn 117 aq+++++a ++q+ e+l ++ dek+ FUN_001116-T5 263 AQQREELAFLEQQLskvtEDLFKIRDEKESLS 294 56666666555443222278888889987655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1078 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2662 (0.104208); expected 510.9 (0.02) Passed bias filter: 810 (0.0317087); expected 510.9 (0.02) Passed Vit filter: 94 (0.00367978); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.55u 0.39s 00:00:00.94 Elapsed: 00:00:00.43 # Mc/sec: 10136.66 // Query: FUN_001118-T1 [L=260] Description: FUN_001118 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-77 259.3 0.0 6e-77 259.1 0.0 1.0 1 Carb_anhydrase Eukaryotic-type carbonic anhydrase ------ inclusion threshold ------ 0.19 12.4 0.0 0.32 11.6 0.0 1.3 1 DUF2325 Uncharacterized protein conserved in bacteria Domain annotation for each model (and alignments): >> Carb_anhydrase Eukaryotic-type carbonic anhydrase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 259.1 0.0 4.7e-81 6e-77 1 255 [] 9 259 .. 9 259 .. 0.95 Alignments for each domain: == domain 1 score: 259.1 bits; conditional E-value: 4.7e-81 Carb_anhydrase 1 egpskWkekypsc.ggkrQSPInietkkvkvdpslkplefegydkkkkkltltNnGhtvqvelees.ekvtisggpleekeYraeqlhfHWgsss 93 +gp++W ++ p + gkrQSPI++ +++vk d+sl+pl ++ y + +k + NnGh+vq+ + s + +++sggpl+ k+Y++eq+hfHWg+++ FUN_001118-T1 9 NGPANWYKSCPIAfIGKRQSPIDLIDNEVKRDSSLEPLVVS-YP-PFSKGKFLNNGHSVQFVPDASnNLSELSGGPLA-KKYKFEQFHFHWGDKD 100 689***999998879*************************8.88.77889************9988666********7.58************** PP Carb_anhydrase 94 skGSEhtidgkrypaElhivhyns.kykslsealk..kpdglavlavllevgdeeeneelekivealkkikkkgkstelk.efslsdLlpeedlt 184 s+GSEh ++gk y+aElh+vh++ +++s+ e +k k++gl+vl+++l+vg e n++l++i++ l k+kk+g+s l+ ef++++++p +dlt FUN_001118-T1 101 SEGSEHRVNGKMYSAELHFVHWDCeTHASFPETVKanKRNGLCVLGFFLKVGAE--NAALKPITDMLPKVKKAGSSEPLAiEFDMRSVMP-KDLT 192 ***********************99999**9998744679***********987..9*******************99999*********.9*** PP Carb_anhydrase 185 kYyrYeGSLTtPpcsesVtWivfkepieiseeqlekfrkllsseeeeekeplvnnfRpvqplngRkVrasf 255 +Yy+Y+GSLTtPp+ e+V W+vfkep+e+s +q+e+fr + + ++e plv n+Rp+ p+++R+V asf FUN_001118-T1 193 DYYTYDGSLTTPPLLECVKWVVFKEPLEVSAAQMEAFRAVENGNGE----PLVGNYRPPCPVHSRTVAASF 259 ****************************************999998....*****************9986 PP >> DUF2325 Uncharacterized protein conserved in bacteria (DUF2325) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 2.5e-05 0.32 20 74 .. 85 142 .. 81 147 .. 0.79 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.5e-05 DUF2325 20 eklgg...klkvfdgkkkkkskklekkigkaDlvvlftdtvsHkavkkakkaakkkgk 74 +k+++ ++++ d+ +++++++++ k+ +a+l + d+ H+++ ++ ka k++g FUN_001118-T1 85 KKYKFeqfHFHWGDKDSEGSEHRVNGKMYSAELHFVHWDCETHASFPETVKANKRNGL 142 5555550145555666777777******************************999985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (260 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 439 (0.0171854); expected 510.9 (0.02) Passed bias filter: 419 (0.0164024); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2653.76 // Query: FUN_001119-T1 [L=169] Description: FUN_001119 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-13 50.2 0.5 4.2e-13 49.8 0.5 1.1 1 UTP20_C Small subunit processome component 20 homolog, C-te Domain annotation for each model (and alignments): >> UTP20_C Small subunit processome component 20 homolog, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.8 0.5 1.6e-17 4.2e-13 147 284 .. 2 164 .. 1 168 [. 0.86 Alignments for each domain: == domain 1 score: 49.8 bits; conditional E-value: 1.6e-17 UTP20_C 147 aknlvylskaler....sdeel.........................rwlvekLasicrfEvvkqpnetlkRlsiFklaAalvlkadserldvvve 213 +knlv+l+k+l+ + l kL + E +t+kR ++ +l+ a++++ ++ +++ ++ FUN_001119-T1 2 VKNLVFLAKTLQIlsseG---SpiaennrdrhasnenltskegpltlKDLLRKLNKEATLEDSLATRQTQKRNCVLRLVSAVAINLGRDGVEPFLT 94 689999999987754440...1445555555666666699999999999*********************************************** PP UTP20_C 214 sllplLvREmqgkstknteeLqkialEvaeviKkkiGeeeyakklaecqklaaekleeRKRkkkEeavtdp 284 ++l ++RE++ s+ ++ +L+++alE++++iK + ++++a qk+ ++ e+R Rkkk + v + FUN_001119-T1 95 DILKPIHRELEIPSSFKDPDLKTLALEALDLIKGLAKRDAVSQAYAILQKATIKTRETR-RKKKALEVSHV 164 **************************************************988877777.77777777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (169 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 697 (0.0272852); expected 510.9 (0.02) Passed bias filter: 417 (0.0163241); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1695.25 // Query: FUN_001120-T1 [L=295] Description: FUN_001120 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-06 27.1 0.0 8.7e-06 25.7 0.0 1.7 2 UTP20_C Small subunit processome component 20 homolog ------ inclusion threshold ------ 0.029 13.6 0.1 0.46 9.7 0.1 2.2 2 VPS15-like_hel VPS15-like, helical domain 0.029 15.1 0.0 18 6.4 0.0 3.1 2 HEAT HEAT repeat Domain annotation for each model (and alignments): >> UTP20_C Small subunit processome component 20 homolog, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 0.39 3.3e+03 92 157 .. 72 98 .. 48 114 .. 0.58 2 ! 25.7 0.0 1e-09 8.7e-06 2 113 .. 124 251 .. 123 283 .. 0.77 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 0.39 UTP20_C 92 aevqLsaarllgqllselekeflksrsdpsvrdliewtlwqLkskklseelaeQaaknlvylskal 157 ++vqL + +e lae a+ + l++ l FUN_001120-T1 72 QNVQLQC---------------------------------------RQETLAENASFFFIPLTTRL 98 4444433.......................................33445555555555555555 PP == domain 2 score: 25.7 bits; conditional E-value: 1e-09 UTP20_C 2 rsiaiqllvqlskvegeafenrlkeilpllseilkadsl..sensee....s............iteildsltsilsnlkesaeelaeeellesil 79 +++a+q+ + + +veg++f +l+++lp +s+ + + + +e+ + s + ++l l++i+++++ ++ +ee +++i+ FUN_001120-T1 124 QRLAAQVWGLFVEVEGKNFDRKLTNLLPIISDAIVPERFegEECVNDkevdSsgqiskrpkdhlLFNVLSLLAKIMKECQVIKSPSRQEE-MTKIW 218 679****************************9997766622222211234515666678888889***************7666666665.677** PP UTP20_C 80 ksleslakclksaevqLsaarllgqllselekef 113 s+e+ + + v+L+++rllg l+++ + e FUN_001120-T1 219 GSVEEHLL-HPHVWVRLASSRLLGLLFAAWKPEE 251 ***99875.56789*************9876554 PP >> VPS15-like_hel VPS15-like, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.016 1.3e+02 41 72 .. 91 122 .. 72 135 .. 0.89 2 ? 9.7 0.1 5.4e-05 0.46 254 313 .. 190 254 .. 182 283 .. 0.71 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.016 VPS15-like_hel 41 ilPYlvsllsDesarVraaairtltklLslvk 72 ++P l++D+sa++r a +t+ lL++v FUN_001120-T1 91 FIPLTTRLVNDDSANCRQLAGYTIQLLLKKVA 122 589999*******************9999986 PP == domain 2 score: 9.7 bits; conditional E-value: 5.4e-05 VPS15-like_hel 254 kalkalasLvelgllekrv.....llelleevlpllvHPnewiRlavvelivalskklsladvqc 313 ++l+ la+++++ + k+ ++++ +v l+HP w+Rla +l+ l +++ + + FUN_001120-T1 190 NVLSLLAKIMKECQVIKSPsrqeeMTKIWGSVEEHLLHPHVWVRLASSRLLGLLFAAWKPEELVT 254 56666666664433332222344499999*******************99999888888766555 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.0021 18 2 29 .. 92 119 .. 91 121 .. 0.84 2 ? 5.2 0.0 0.0055 46 5 27 .. 221 243 .. 217 245 .. 0.86 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0021 HEAT 2 lplllkllnDpspeVReaAaeaLgalae 29 +pl +l nD+s++ R+ A +++ l++ FUN_001120-T1 92 IPLTTRLVNDDSANCRQLAGYTIQLLLK 119 67767788*************9998877 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0055 HEAT 5 llkllnDpspeVReaAaeaLgal 27 + ++l +p+ VR+a+ + Lg l FUN_001120-T1 221 VEEHLLHPHVWVRLASSRLLGLL 243 678899***********999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 630 (0.0246624); expected 510.9 (0.02) Passed bias filter: 498 (0.019495); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2874.07 // Query: FUN_001121-T1 [L=490] Description: FUN_001121 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-81 272.7 3.8 2.7e-81 272.7 3.8 1.8 2 UTP20 U3 small nucleolar RNA-associated protein 20 do 5.7e-05 23.7 2.7 0.00023 21.7 0.1 2.6 3 BIG2_C BIG2 C-terminal domain 0.0024 18.3 2.0 0.13 12.7 0.0 3.0 3 TPR_Trm732_C Trm732, C-terminal TPR repeats ------ inclusion threshold ------ 0.23 12.3 0.2 16 6.6 0.0 2.9 2 HEAT HEAT repeat 1.1 9.5 5.3 0.88 9.8 0.1 2.7 3 DCB Mon2/Sec7/BIG1-like, dimerisation and cyclophil Domain annotation for each model (and alignments): >> UTP20 U3 small nucleolar RNA-associated protein 20 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 272.7 3.8 5.3e-85 2.7e-81 2 220 .. 105 323 .. 104 324 .. 0.99 2 ? -1.0 0.0 0.27 1.4e+03 169 199 .. 404 434 .. 394 459 .. 0.81 Alignments for each domain: == domain 1 score: 272.7 bits; conditional E-value: 5.3e-85 UTP20 2 kdeekedvlrvpvalaivkllkkLpeksleaqlpglltkvcqlLrsrsqevRdaaRetLvkilevLGpkyLpfilkelksaLtrGyqlhVlsytvh 97 k e+++++lrvpv lai+kll+ Lpe++l+ +lpgll+k c++L+s+s+evR aaRetL+ki+ +LG kyLpfi+++l+ +L+ GyqlhVls+t+h FUN_001121-T1 105 KAEDEKEILRVPVILAIIKLLQALPEHALHLHLPGLLLKACNILKSKSNEVRVAARETLTKITISLGIKYLPFIVEQLRGVLRTGYQLHVLSFTLH 200 566779****************************************************************************************** PP UTP20 98 alLealepeleegdlDscledileiiledifgevaeekeveeikkkvkEakssksydtlellaklvsfsaiskllkplkeileetesaktlkkvee 193 lLe+l+++l++gdlD l+di+e+++ed+fgeva+e+eve+i +k++Eak+ ks dt+e+l+++v+ ++++kl++plkeil++t+s+kt + vee FUN_001121-T1 201 RLLEKLSSSLNPGDLDPGLQDIVEVLVEDLFGEVAKEREVEKIANKLPEAKTCKSCDTFEILSRFVEAQSLNKLITPLKEILDSTKSQKTARLVEE 296 ************************************************************************************************ PP UTP20 194 lLrriaaGLseNkslssedllilvyel 220 +Lrri+ GL++N+s+++ li++++l FUN_001121-T1 297 VLRRISVGLQSNQSMTVPLQLIFIHGL 323 *************************97 PP == domain 2 score: -1.0 bits; conditional E-value: 0.27 UTP20 169 skllkplkeileetesaktlkkveelLrria 199 ++l p+ e+l++ ++k k v+ + r ++ FUN_001121-T1 404 LRMLDPFVELLTDCLESKHNKMVTVAVRSVC 434 4889999999999888888888887777766 PP >> BIG2_C BIG2 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.1 4.4e-08 0.00023 110 176 .. 97 163 .. 75 164 .. 0.80 2 ? -2.8 0.0 1.6 7.9e+03 24 24 .. 288 288 .. 258 319 .. 0.49 3 ? 1.2 0.1 0.089 4.5e+02 107 161 .. 406 460 .. 378 466 .. 0.73 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 4.4e-08 BIG2_C 110 eYlsld..eeekqrelaawtplvveiLqgllaleeekFkkhlpelypllvdLilveespevraaLreil 176 ++++l+ + e ++e + p++++i++ l al+e +++ hlp l +++++++ +s+evr+a re l FUN_001121-T1 97 SFHRLSrmKAEDEKE-ILRVPVILAIIKLLQALPEHALHLHLPGLLLKACNILKS-KSNEVRVAARETL 163 344442222234555.4899***********************************.********99876 PP == domain 2 score: -2.8 bits; conditional E-value: 1.6 BIG2_C 24 e 24 + FUN_001121-T1 288 Q 288 1 PP == domain 3 score: 1.2 bits; conditional E-value: 0.089 BIG2_C 107 ileeYlsldee..ekqrelaawtplvveiLqgllaleeekFkkhlpelypllvdLil 161 +l+ +++l ++ e++ + + + v + +l +++ +++ +p++ ++l +L++ FUN_001121-T1 406 MLDPFVELLTDclESKH--NKMVTVAVRSVCQLVKFPLPSLARFVPKIGKQLFQLLK 460 44555555333222333..36888888899999999999999999999999999986 PP >> TPR_Trm732_C Trm732, C-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.3 0.027 1.4e+02 63 139 .. 108 183 .. 74 194 .. 0.68 2 ? -0.1 0.0 0.2 1e+03 51 127 .. 200 277 .. 190 297 .. 0.65 3 ! 12.7 0.0 2.5e-05 0.13 70 126 .. 384 438 .. 368 457 .. 0.79 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.027 TPR_Trm732_C 63 eeeaseslfpiLllLsrLqpsspeeeeseaeslsefvplvlkclaskiwkvRemaAralvalvsss..evlslllsllk 139 +e++ ++ iL +++ Lq+ e++ + +l ++ ++l+sk +vR +a ++l+ ++ s ++l +++++l+ FUN_001121-T1 108 DEKEILRVPVILAIIKLLQALP---EHALHLHLPGLLLKACNILKSKSNEVRVAARETLTKITISLgiKYLPFIVEQLR 183 2333346666777777777654...3455677777877788899********999999988754321245666666665 PP == domain 2 score: -0.1 bits; conditional E-value: 0.2 TPR_Trm732_C 51 eeLeeaveslsseeeaseslfpiLllLsrLqpsspeeeeseaeslsefvplvlkclaskiwkv..RemaAralvalvss 127 ++L e+++s + + ++l+ i+ +L + +e+e e++++ +p + c + +++ R + A++l l+++ FUN_001121-T1 200 HRLLEKLSSSLNPGDLDPGLQDIVEVLVEDLFGE-VAKEREVEKIANKLPEAKTCKSCDTFEIlsRFVEAQSLNKLITP 277 3343444444455667788888887665433333.45566778888888888888888888765588888888888765 PP == domain 3 score: 12.7 bits; conditional E-value: 2.5e-05 TPR_Trm732_C 70 lfpiLllLsrLqpsspeeeeseaeslsefvplvlkclaskiwkvRemaAralvalvs 126 l+ + llL++ ++s+ ++e++ + l++fv+l+ cl+sk k+ +a r+++ lv+ FUN_001121-T1 384 LQMLYLLLKKGKIST--SNEEQLRMLDPFVELLTDCLESKHNKMVTVAVRSVCQLVK 438 444455666666554..46677899****************************9996 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.0032 16 7 28 .. 146 167 .. 141 170 .. 0.86 2 ? 2.7 0.0 0.057 2.9e+02 2 29 .. 411 438 .. 410 439 .. 0.91 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0032 HEAT 7 kllnDpspeVReaAaeaLgala 28 + l+++s eVR aA e+L +++ FUN_001121-T1 146 NILKSKSNEVRVAARETLTKIT 167 6689************999886 PP == domain 2 score: 2.7 bits; conditional E-value: 0.057 HEAT 2 lplllkllnDpspeVReaAaeaLgalae 29 + ll +l++++ + A++++++l++ FUN_001121-T1 411 VELLTDCLESKHNKMVTVAVRSVCQLVK 438 678999********************98 PP >> DCB Mon2/Sec7/BIG1-like, dimerisation and cyclophilin-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 0.65 3.3e+03 82 108 .. 100 132 .. 89 168 .. 0.48 2 ? 1.1 0.2 0.078 4e+02 34 87 .. 273 327 .. 239 337 .. 0.74 3 ? 9.8 0.1 0.00017 0.88 43 86 .. 397 439 .. 382 463 .. 0.77 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.65 DCB 82 kLishdaisesa......ikeiletlielmelg 108 +L+ ++a +e++ i i++ l++l e + FUN_001121-T1 100 RLSRMKAEDEKEilrvpvILAIIKLLQALPEHA 132 444444444444222222333333333333333 PP == domain 2 score: 1.1 bits; conditional E-value: 0.078 DCB 34 kailkLktvksss.eqsllseseeilkPlvlacetknaklvkialqslqkLishd 87 k+i Lk++ +s+ q+ ++ +ee+l + ++++ + v + l ++ L s++ FUN_001121-T1 273 KLITPLKEILDSTkSQKTARLVEEVLRRISVGLQSNQSMTVPLQLIFIHGLASEN 327 5555566554444355566667778888888888888888887777777777765 PP == domain 3 score: 9.8 bits; conditional E-value: 0.00017 DCB 43 kssseqsllseseeilkPlvlacetknaklvkialqslqkLish 86 ++s+e++l+ + +++ l +e+k+ k+v++a+ s+ +L++ FUN_001121-T1 397 STSNEEQLRML-DPFVELLTDCLESKHNKMVTVAVRSVCQLVKF 439 44555566555.88888888889****************99976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (490 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1190 (0.0465845); expected 510.9 (0.02) Passed bias filter: 815 (0.0319045); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4726.06 // Query: FUN_001122-T1 [L=1685] Description: FUN_001122 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-146 488.9 4.2 2.7e-146 488.9 4.2 2.7 3 UTP20_N U3 small nucleolar RNA-associated protein 20, N-t 0.0012 18.9 3.2 1.6 8.6 0.2 3.9 3 TPR_Trm732 Trm732, TPR repeats ------ inclusion threshold ------ 0.13 12.6 7.9 9.3 6.5 0.1 4.5 4 TFCD_C Tubulin folding cofactor D C terminal 0.26 12.5 0.7 2.5 9.4 0.0 3.0 3 CdiI_2 CdiI immunity protein 7.3 6.9 8.7 0.97 9.8 0.2 3.8 5 BP28CT BP28CT (NUC211) domain Domain annotation for each model (and alignments): >> UTP20_N U3 small nucleolar RNA-associated protein 20, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.2 0.2 1e+03 400 447 .. 108 161 .. 67 194 .. 0.45 2 ? -0.5 0.4 0.08 4.1e+02 14 62 .. 313 360 .. 275 430 .. 0.53 3 ! 488.9 4.2 5.4e-150 2.7e-146 4 616 .] 928 1551 .. 926 1551 .. 0.93 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.2 UTP20_N 400 keveiLsrlapyvedseqas........sLlelllplLrkpskrvsektkvdlLki 447 ++ +Ls l +v+ +++ + s+ e++l+lL + s ++++ ++++ FUN_001122-T1 108 GSLALLSLLDLVVQLAKDLQgdfypyfgSFFEIFLSLLSRYS--QEPRVLECIFQT 161 333334444444444433333344444444444444444433..344444444444 PP == domain 2 score: -0.5 bits; conditional E-value: 0.08 UTP20_N 14 fakfknpkalykseelyealldlLsngdaevQklALkclltwkdpavvp 62 ++++ ++++y+ e+l++ + L+++ + v kl L+c ++wk++++ FUN_001122-T1 313 VQELERLSSIYNGEQLNSEQVESLKSQLSRVVKL-LDCWVSWKSENLIS 360 3333344444444444444444444444444444.44444444444433 PP == domain 3 score: 488.9 bits; conditional E-value: 5.4e-150 UTP20_N 4 rkdlkalLklfakfknpkalykseelyealldlLsngdaevQklALkclltwkdpavvpykenLknLlddkrfrdeLtkflqseeesvieeehr 97 +k l +L+l++ fk+pk+l+k+ e+ ++l ++L+++d evQ+l kcl+++k +++ pyken+++Ll+d++fr+eL++f ++eee +++ +hr FUN_001122-T1 928 TKSLCIHLSLLTVFKSPKSLFKEREVMQLLNKFLTHRDGEVQTLVVKCLMNYKFNYLCPYKENIERLLQDESFREELAHFSVDEEEGIVDVSHR 1021 678889**************************************************************************************** PP UTP20_N 98 eelmpvllRiLyGrmiskkg.rssgkagqearrkavLrfLaglseeelglFldlaleplkdvsvlkesadeekefvekkeeiesevlplrrqlG 190 e lmp+l+R+LyG+m+ +g ++sgkag +arr++vLr+La+++++el+ F+dl+l+p+k++ +k+ +v+k+ +s+++pl++q++ FUN_001122-T1 1022 EGLMPILIRLLYGKMLRFTGpGTSGKAGVSARRSVVLRYLASCPPNELQIFMDLVLAPFKHLCTAKDPG---RIIVTKD---LSKIVPLKKQQS 1109 ************************************************************996444432...2222333...6888******** PP UTP20_N 191 flnlledvlkeLgskl..apylpkllnillyclvaaqrrlskekeeeeeeesllkllrniRqlglkclvdlfknledffdwspyldaifeevis 282 fl++ +++l+ Lg+k+ +++ + +l+i+l +l++ +l+++ + + ++l++iRql++ +l+++f+nl df d +p +d +f+ +++ FUN_001122-T1 1110 FLSMASQILNLLGEKIvaSSFHSCILQIILSLLSSCVLALEQR---HLVRLPFISQLKTIRQLAVTRLTEFFENLIDF-DVKPICDGVFSYAVW 1199 ***************9988999********6555555455555...33334456**********************99.9************** PP UTP20_N 283 prleklasEnlqspSallkLfltWsknpryaplLvk.....edsavlpkvielLsaekakeeVvlfvldilenllklaeeeeeee......... 362 p++e+l +++q+p+al+kL++tWsk+pry+plL + +d ++++ v+++L +k++++ + +v+++++nll++ +e+++ FUN_001122-T1 1200 PQIENLCLDSTQNPTALFKLLFTWSKHPRYLPLLSRkslekPDLSIMSCVFACLRFSKTSPAMLAMVIEMTDNLLSAVGSEDSDLlelgcelrp 1293 ****************************************************************************988877755********* PP UTP20_N 363 .......eeeeiksellaphvsslLkslsallers.........kkkskellskeveiLsrlapyvedseqassLlelllplLrkpskrvsekt 440 ++ ++++ l+ ph+s++L+ ls+ ++++ k + + +e+++Ls+l+p+v+d++q+++Lle l+p+L +e + FUN_001122-T1 1294 psgysleNRPSYGTLLVLPHLSEILECLSRSVKQAvennekiqgKF-KLAIPPRELSVLSKLSPFVQDAKQSATLLEALIPALSDAR---KEGA 1383 *******8889*********************99999988888543.68999*******************************8766...7777 PP UTP20_N 441 kvdlLkilsnllplydeeedeeselpeklyktlsslfstfkdresRelLvkvlkalakkdpel.eevaelvadLNayskkrldepDFdrRlsAF 533 ++L++++ ll + +e+p ++ l++ fs++kdr++R++L++v+ +l++ dp++ + +el++ +N+++ krl+epD+d+Rl+ F FUN_001122-T1 1384 ANRILTTVKGLLAN--------VESPMTFVIPLCKPFSWIKDRSTRQCLCEVFLKLSNIDPSFsLKASELLRMINSWDDKRLEEPDYDTRLAGF 1469 88************........889*************************************867999************************** PP UTP20_N 534 kkinee.eyksltakqwlpllynclffikdeeElaiRsnAslcLkrfidaaaekseeeeakeefeellkdvllpalkkglrsks 616 +++ + +l+++++l +l+nc++f+ ++ ++++R++ ++++ ++ ++ +ks+e++ e+f+ l+ + llpa kk++ sk+ FUN_001122-T1 1470 AEVRAClQRGELKEEEILAILNNCIYFVLNSTDMSLRDSGGSSMSCILRYVLQKSAENK--EAFNLLVIENLLPACKKAIASKN 1551 *****977789*****************************************9988884..78*****************9986 PP >> TPR_Trm732 Trm732, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.03 1.5e+02 61 111 .. 532 581 .. 498 590 .. 0.79 2 ! 8.6 0.2 0.00031 1.6 58 127 .. 615 687 .. 592 700 .. 0.79 3 ! 5.8 0.0 0.0022 11 89 151 .. 1455 1517 .. 1438 1562 .. 0.88 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.03 TPR_Trm732 61 lllscLkigqelsiieeldllksesfleelLqhdseklrldaleLltespk 111 ++l+c+k +++ e+l+ ++++ ++e lL+++ ++r+++l++l ++ + FUN_001122-T1 532 VCLPCIKPLDTSRCCEKLRGMIQS-TIELLLSNERARHRVACLSVLSQAIQ 581 688888888888899998877555.78******************988765 PP == domain 2 score: 8.6 bits; conditional E-value: 0.00031 TPR_Trm732 58 klalllscLkigqelsi...ieeldllksesfleelLqhdseklrldaleLltespkkskpisseefdllken 127 l+++ +++++ +++i + +l ++ s+++ L++ s+ +rl++l++l+ ++ +p++s++++l + + FUN_001122-T1 615 ILQACYKLVTVASQQEIqgfLTAENLAETYSYVRLNLCSASHVIRLATLKILACFDQHEMPLASSKYALFQLC 687 45678888888888776222444677888999***********************************998876 PP == domain 3 score: 5.8 bits; conditional E-value: 0.0022 TPR_Trm732 89 elLqhdseklrldaleLltespkkskpisseefdllkenldlffvetdvevRnqfisllkkfi 151 + L++ ++++rl+ + + ++ + + + e++++l++++ +++++td++ R++ s++ ++ FUN_001122-T1 1455 KRLEEPDYDTRLAGFAEVRACLQRGELKEEEILAILNNCIYFVLNSTDMSLRDSGGSSMSCIL 1517 5578889999999999999999999999*************************9988887655 PP >> TFCD_C Tubulin folding cofactor D C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.1 0.0018 9.3 92 154 .. 100 168 .. 97 193 .. 0.69 2 ? 3.6 0.1 0.015 76 120 175 .. 362 417 .. 291 421 .. 0.85 3 ? 3.6 0.5 0.014 72 115 163 .. 1105 1153 .. 1094 1177 .. 0.77 4 ? -2.0 0.0 0.77 3.9e+03 100 148 .. 1364 1412 .. 1361 1429 .. 0.80 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0018 TFCD_C 92 lteslvkassaaLleylkslkd..ekdeeele....kllsdlldileenlkddrvvvPllktldlLles 154 l+e+l+ + s aLl+ l+ + + ++ + +++ ++++ +l++l+++ ++ rv+ ++++tl +L++ FUN_001122-T1 100 LKEHLQIPGSLALLSLLDLVVQlaKDLQGDFYpyfgSFFEIFLSLLSRYSQEPRVLECIFQTLGHLFKF 168 5677777777777777744444443333333344559*****************************964 PP == domain 2 score: 3.6 bits; conditional E-value: 0.015 TFCD_C 120 lekllsdlldileenlkddrvvvPllktldlLlesgvfeelleeessflekllelv 175 k++ l + ++ + +d ++ Pllk ++Ll +++ e +++++++ +k+++ v FUN_001122-T1 362 PVKIFHVLQGMITRDFLSDPITSPLLKLTSSLLLASFTEFPADHQKELTSKVFDTV 417 4577777888889999*****************99988888887779999999887 PP == domain 3 score: 3.6 bits; conditional E-value: 0.014 TFCD_C 115 kdeeelekllsdlldileenlkddrvvvPllktldlLlesgvfeellee 163 k+++++ +++s++l++l e+ + ++l+++ +Ll+s+v++ + + FUN_001122-T1 1105 KKQQSFLSMASQILNLLGEKIVASSFHSCILQIILSLLSSCVLALEQRH 1153 678899999******************************9988654443 PP == domain 4 score: -2.0 bits; conditional E-value: 0.77 TFCD_C 100 ssaaLleylkslkdekdeeelekllsdlldileenlkddrvvvPllktl 148 s++ L + + +l+d+++e + +++l+++ +l + + +v+Pl+k + FUN_001122-T1 1364 SATLLEALIPALSDARKEGAANRILTTVKGLLANVESPMTFVIPLCKPF 1412 45555555566677889999**************99999*****99866 PP >> CdiI_2 CdiI immunity protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.4 1.2e+04 17 55 .. 68 104 .. 60 105 .. 0.70 2 ? -1.4 0.1 1.1 5.7e+03 16 67 .. 281 335 .. 279 341 .. 0.62 3 ? 9.4 0.0 0.00048 2.5 33 80 .. 1256 1298 .. 1253 1301 .. 0.85 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.4 CdiI_2 17 wdiegetpeeiledyvssespelvaalvdeleeLlaasl 55 +++ ++++ + yv+s +++ + ++e+ +Ll+++l FUN_001122-T1 68 CTLHFQNFSSKVSAYVQSL--AQLVHHKEEVIDLLKEHL 104 4555666666777788775..777788888888888765 PP == domain 2 score: -1.4 bits; conditional E-value: 1.1 CdiI_2 16 Dwdiegetpeeiledyvssespelv....aalvdeleeLlaasldeeeleeaflke 67 w++ +et e+le + + ++ ++lv+ele+L + + e+ l+++ +++ FUN_001122-T1 281 QWELVFETLAEMLERMAEHTGKKHCqvveRSLVQELERLSSIYNGEQ-LNSEQVES 335 56677777666666666555444331112579999999999888776.66655555 PP == domain 3 score: 9.4 bits; conditional E-value: 0.00048 CdiI_2 33 ssespelvaalvdeleeLlaasldeeeleeaflkelgcevsPeadglt 80 s++sp+++a++++ +++Ll+a +e+ + + elgce++P+ g++ FUN_001122-T1 1256 SKTSPAMLAMVIEMTDNLLSAVGSED--SDLL--ELGCELRPP-SGYS 1298 6789*******************985..4444..99*******.7776 PP >> BP28CT BP28CT (NUC211) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.2 0.00019 0.97 84 143 .. 112 167 .. 87 181 .. 0.85 2 ? -4.2 0.0 3.7 1.9e+04 6 20 .. 214 228 .. 212 232 .. 0.84 3 ? -3.2 0.0 2 1e+04 4 23 .. 498 517 .. 497 522 .. 0.81 4 ? -1.9 0.0 0.74 3.8e+03 106 140 .. 740 773 .. 733 781 .. 0.73 5 ? -1.0 0.5 0.39 2e+03 81 129 .. 1104 1153 .. 1094 1181 .. 0.62 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00019 BP28CT 84 litfykllnklaekLksivtsYasyllenavelLkalnskkeeskeLlrlvlstLtksfe 143 l+++ l+ +la+ L++ + +Y++ ++e +++lL++++ ++ l+ + +tL + f+ FUN_001122-T1 112 LLSLLDLVVQLAKDLQGDFYPYFGSFFEIFLSLLSRYS----QEPRVLECIFQTLGHLFK 167 689999****************************8887....456677778888877776 PP == domain 2 score: -4.2 bits; conditional E-value: 3.7 BP28CT 6 lkklfklllkaldlR 20 + lf++l++ald++ FUN_001122-T1 214 SGRLFDILFSALDMQ 228 5689*********96 PP == domain 3 score: -3.2 bits; conditional E-value: 2 BP28CT 4 knlkklfklllkaldlRrqq 23 k+ k++k++l+ l++R+ + FUN_001122-T1 498 KQGAKMSKFFLDNLNIRQIA 517 566789***********865 PP == domain 4 score: -1.9 bits; conditional E-value: 0.74 BP28CT 106 asyllenavelLkalnskkeeskeLlrlvlstLtk 140 ++ l+++++el+++++++ +++k+ ++ ++L++ FUN_001122-T1 740 FNLLWDPVIELITSFTRG-DDAKHFWEIYRDVLNT 773 6789999*****999865.5666677766666655 PP == domain 5 score: -1.0 bits; conditional E-value: 0.39 BP28CT 81 veRlitfykllnklaekL..ksivtsYasyllenavelLkalnskkeeske 129 ++++++f +++ ++++ L k + s+ s +l+ +++lL+++ e+++ FUN_001122-T1 1104 LKKQQSFLSMASQILNLLgeKIVASSFHSCILQIILSLLSSCVL-ALEQRH 1153 46777888888888887732334567888888888888877753.344444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1685 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1137 (0.0445097); expected 510.9 (0.02) Passed bias filter: 830 (0.0324917); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.57u 0.39s 00:00:00.96 Elapsed: 00:00:00.43 # Mc/sec: 15643.26 // Query: FUN_001123-T1 [L=128] Description: FUN_001123 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00045 21.1 20.1 0.00082 20.3 20.1 1.4 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 5.8 8.1 21.4 2.6 9.2 19.3 1.5 1 PLA2_inh Phospholipase A2 inhibitor Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 20.1 6.4e-08 0.00082 3 81 .. 20 106 .. 19 107 .. 0.93 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 6.4e-08 UPAR_LY6 3 lrCysClgessssccssgs...sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCns 81 ++C +C +++s ++c++ + C +g + C+++++ ++ + ++ + +kgC + c ++++ + + +t + +cc+sd Cns FUN_001123-T1 20 IKCQECSSTTSMEECKKKEkekDCGEGFDRCIKRSFDYKLSILQIKSFSKGCstKATCDADQKLKICKeakGTTCEWNCCDSDGCNS 106 79*************9999999******************************9888898888888888888899************8 PP >> PLA2_inh Phospholipase A2 inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 19.3 0.0002 2.6 2 82 .. 21 105 .. 20 106 .. 0.81 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0002 PLA2_inh 2 sCeiCvnlG..kdCeg..ykeeCdsneDaCvtvllevssaplslrlihknCfssdlCkLekldvnigkelylrgkiaCCdeeeCe 82 +C+ C + ++C++ +++C++ D C + + + l +++ +k C + +C ++ ++ +CCd + C+ FUN_001123-T1 21 KCQECSSTTsmEECKKkeKEKDCGEGFDRCIKRSFDYKLSILQIKSFSKGCSTKATCDADQKLKICKEAKGTTCEWNCCDSDGCN 105 6888876542279*98656788************************************997544444555567899********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1594 (0.0623997); expected 510.9 (0.02) Passed bias filter: 480 (0.0187904); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1279.85 // Query: FUN_001124-T1 [L=113] Description: FUN_001124 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0011 19.8 21.2 0.0011 19.8 21.2 1.4 2 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 1.4 9.9 30.3 3 8.9 8.5 2.4 2 Paramecium_SA Paramecium surface antigen domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 21.2 8.8e-08 0.0011 3 81 .. 5 91 .. 4 92 .. 0.92 2 ? -3.2 0.1 1.4 1.8e+04 23 30 .. 105 112 .. 103 113 .] 0.55 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 8.8e-08 UPAR_LY6 3 lrCysClgessssccssgs...sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCns 81 ++C +C++++s ++c++ + C +++ C+++++ +++ k ++ kgC + c ++++ + + +t + +cc+sd Cns FUN_001124-T1 5 IKCQTCTSTTSMKDCKKNEkkmDCGGDSDRCFKSSFDYKDLTGKKKIFEKGCanKATCDAEQTLKGCKkakGTTCEWNCCDSDGCNS 91 79*************999999******************999999*******99888888888888778888999***********8 PP == domain 2 score: -3.2 bits; conditional E-value: 1.4 UPAR_LY6 23 CpkgdtqC 30 C+ +++C FUN_001124-T1 105 CTLVSKMC 112 55555555 PP >> Paramecium_SA Paramecium surface antigen domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 8.5 0.00023 3 28 58 .. 8 37 .. 4 39 .. 0.90 2 ? 6.7 13.8 0.0011 14 20 58 .. 53 86 .. 46 92 .. 0.84 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00023 Paramecium_SA 28 atCssyttqaqCkknktggkClwdgstaCvd 58 +tC+s+t+ + Ckkn+++ +C d+ C++ FUN_001124-T1 8 QTCTSTTSMKDCKKNEKKMDCGGDSD-RCFK 37 79**********************95.9987 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0011 Paramecium_SA 20 gtgCvekkatCssyttqaqCkknktggkClwdgstaCvd 58 ++gC +k atC + +t + Ckk+ +g++C w+ C + FUN_001124-T1 53 EKGCANK-ATCDAEQTLKGCKKA-KGTTCEWNC---CDS 86 479****.***************.9******97...444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1197 (0.0468585); expected 510.9 (0.02) Passed bias filter: 287 (0.0112351); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1155.54 // Query: FUN_001125-T1 [L=98] Description: FUN_001125 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0018 19.2 11.7 0.0028 18.5 11.7 1.3 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 1.4 10.2 12.5 2.7 9.3 12.5 1.5 1 Toxin_TOLIP Snake toxin and toxin-like protein Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 11.7 2.2e-07 0.0028 14 81 .. 4 76 .. 1 77 [. 0.89 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 2.2e-07 UPAR_LY6 14 ssccssgssCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCns 81 +++ ++++sC + Cv+ ++ ++ +g+++++ kgC + c + ++ + + t +++cc+sd Cn FUN_001125-T1 4 CKKKERETSCGGIYDRCVKISYDYKFEGSEVKYFEKGCstKALCDDIEKLQKCKdvgGSTCEFNCCDSDGCNG 76 55566666**999*************************999999999999999888889*************5 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 12.5 0.00021 2.7 16 72 .] 8 75 .. 1 75 [. 0.76 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00021 Toxin_TOLIP 16 lketkCsesekyCvttvtsa....kskklisksCsss..Ce.....essselgvasvsvsCCqtdlCN 72 ++et+C + Cv++ + ++ k +k Cs++ C ++ +++g+++ +++CC++d CN FUN_001125-T1 8 ERETSCGGIYDRCVKISYDYkfegSEVKYFEKGCSTKalCDdieklQKCKDVGGSTCEFNCCDSDGCN 75 256899999999*99999888998778999****99877885544444556666689**********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (98 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 932 (0.0364846); expected 510.9 (0.02) Passed bias filter: 398 (0.0155803); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 979.37 // Query: FUN_001126-T1 [L=128] Description: FUN_001126 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-05 25.0 17.5 4.2e-05 24.4 17.5 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 0.099 13.9 19.7 0.17 13.1 19.7 1.4 1 Toxin_TOLIP Snake toxin and toxin-like protein 0.98 10.6 17.2 1.5 10.0 17.2 1.3 1 PLA2_inh Phospholipase A2 inhibitor Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 17.5 4.9e-09 4.2e-05 3 81 .. 20 106 .. 19 107 .. 0.95 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 4.9e-09 UPAR_LY6 3 lrCysClgessssccssgs...sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCns 81 ++C +C +++s ++c++++ C g++ C+++++ ++ + ++ + +kgC + +c +++ + +t +++cc+sd Cn FUN_001126-T1 20 IKCQECSSTTSMEECKKEEkekDCGGGSDRCFKASFDYKLSILQIKAFSKGCstKAFCDVKEQLRACEsadGATCKFDCCDSDGCNG 106 79**************999999******************************99999*999999999988899*************5 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 19.7 2e-05 0.17 2 72 .] 21 105 .. 20 105 .. 0.78 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2e-05 Toxin_TOLIP 2 kCytCeeeksnsnCl...ketkCsesekyCvttvtsa....kskklisksCsss..Ce.....essselgvasvsvsCCqtdlCN 72 kC +C++++s ++C+ ke++C ++ C ++ + k+ sk Cs++ C + +++ +a+ ++ CC++d CN FUN_001126-T1 21 KCQECSSTTSMEECKkeeKEKDCGGGSDRCFKASFDYklsiLQIKAFSKGCSTKafCDvkeqlRACESADGATCKFDCCDSDGCN 105 8*************94434678*********9999888999779999*****997787432211222333446999********9 PP >> PLA2_inh Phospholipase A2 inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 17.2 0.00018 1.5 2 82 .. 21 105 .. 20 106 .. 0.84 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00018 PLA2_inh 2 sCeiCvnlG..kdCeg..ykeeCdsneDaCvtvllevssaplslrlihknCfssdlCkLekldvnigkelylrgkiaCCdeeeCe 82 +C+ C + ++C++ +++C+ D C + + + l ++ +k C + C +++ ++ k CCd + C+ FUN_001126-T1 21 KCQECSSTTsmEECKKeeKEKDCGGGSDRCFKASFDYKLSILQIKAFSKGCSTKAFCDVKEQLRACESADGATCKFDCCDSDGCN 105 6888876542279*98545678************************************9876666777777899**********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1467 (0.0574281); expected 510.9 (0.02) Passed bias filter: 477 (0.0186729); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1255.86 // Query: FUN_001127-T1 [L=168] Description: FUN_001127 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 15.7 0.3 0.028 14.6 0.3 1.6 1 RAP80_UIM RAP80 N-terminal ubiquitin interaction motif Domain annotation for each model (and alignments): >> RAP80_UIM RAP80 N-terminal ubiquitin interaction motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.3 1.1e-06 0.028 27 49 .. 9 31 .. 5 39 .. 0.86 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 1.1e-06 RAP80_UIM 27 elnsqeekeeeLLRkAiAesLss 49 + q e+ee LL k iA+sLs FUN_001127-T1 9 QAHKQREEEEFLLIKGIANSLSQ 31 6678*****************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1167 (0.0456841); expected 510.9 (0.02) Passed bias filter: 614 (0.024036); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1714.22 // Query: FUN_001128-T1 [L=127] Description: FUN_001128 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.04 15.1 19.6 0.067 14.4 19.6 1.4 1 Toxin_TOLIP Snake toxin and toxin-like protein Domain annotation for each model (and alignments): >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 19.6 2.6e-06 0.067 2 72 .] 21 104 .. 20 104 .. 0.79 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.6e-06 Toxin_TOLIP 2 kCytCeeeksnsnCl...ketkCsesekyCvttvtsa...kskklisksCsss..Ceesss.....elgvasvsvsCCqtdlCN 72 kC +C++++s ++C+ ke++C ++ C ++ + k+ sk Cs++ C ++++ ++g+++ ++ CC++d CN FUN_001128-T1 21 KCQECSSTTSMEECKkkeKEKDCGGGSDRCFKASFDYkliVDVKAFSKGCSTKafCDAEKQlgeceKAGGTTCKFDCCDSDGCN 104 8*************94334678**********99998899778999*****98778855432211144455699*********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (127 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1448 (0.0566843); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1291.42 // Query: FUN_001129-T1 [L=145] Description: FUN_001129 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.028 15.0 0.3 0.036 14.7 0.3 1.2 1 tRNA_lig_kinase tRNA ligase kinase domain 3.8 7.9 9.1 0.13 12.5 2.2 2.1 2 Rad50_zn_hook Rad50 zinc hook motif Domain annotation for each model (and alignments): >> tRNA_lig_kinase tRNA ligase kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.3 2.8e-06 0.036 27 129 .. 6 110 .. 1 121 [. 0.79 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.8e-06 tRNA_lig_kinase 27 ghvqnDnitgkdksklvkealellkkdeskvvlvD.rnnhqkreRkqlfeei..delkeeylsydvnvkvvalsFvdeddleevreitkdRvlk 117 + +q D+i+ k+ ++++ + +++k+ + ++v +D r n ++ e++ +i +l + +y +v+ l Fv d++ee + i+++++ + FUN_001129-T1 6 ADIQVDDIKAKEGKRVCPVCERTIKRTTRNCVNADcRENLKAAEKELQSSDIpgTALVAPISQYRQRVRETQLGFVI-DQNEEAHVIIEEKLSE 98 579********************************666766666665556773234445455688999999999998.5588889999999999 PP tRNA_lig_kinase 118 RGdnhqsikves 129 d+ q + +++ FUN_001129-T1 99 CYDEFQHVPSNH 110 999999887665 PP >> Rad50_zn_hook Rad50 zinc hook motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 2.2 1e-05 0.13 16 50 .. 16 50 .. 12 52 .. 0.71 2 ? -1.8 0.7 0.33 4.2e+03 24 29 .. 125 130 .. 125 131 .. 0.93 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1e-05 Rad50_zn_hook 16 keaegcCPlCgRpLdeehrseLikklqsklerlpe 50 ke + CP+C+R +r+ + + ++ l++ ++ FUN_001129-T1 16 KEGKRVCPVCERTIKRTTRNCVNADCRENLKAAEK 50 66667*******99998887666666666665555 PP == domain 2 score: -1.8 bits; conditional E-value: 0.33 Rad50_zn_hook 24 lCgRpL 29 +C+R++ FUN_001129-T1 125 VCSRKF 130 8***99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (145 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1172 (0.0458798); expected 510.9 (0.02) Passed bias filter: 609 (0.0238403); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1487.85 // Query: FUN_001130-T1 [L=789] Description: FUN_001130 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-57 196.0 22.3 1.8e-57 195.4 22.3 1.2 1 7tm_3 7 transmembrane sweet-taste receptor of 3 GCPR 1.2e-55 189.5 0.0 1.8e-55 188.9 0.0 1.2 1 ANF_receptor Receptor family ligand binding region 1.7e-05 25.2 0.0 7.6e-05 23.0 0.0 2.1 1 Peripla_BP_6 Periplasmic binding protein Domain annotation for each model (and alignments): >> 7tm_3 7 transmembrane sweet-taste receptor of 3 GCPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 195.4 22.3 2.1e-61 1.8e-57 6 252 .] 484 742 .. 480 742 .. 0.88 Alignments for each domain: == domain 1 score: 195.4 bits; conditional E-value: 2.1e-61 7tm_3 6 plgivllalaalgilltlavlvvfikhrntpvvkasnrelsfllLlglllcflsvflfigkps..dvtCllrqwlfglgftlcfscllaKtwrivl 99 l++ ++++lg+++++++l+++i+h+n +++k+s+++l++l++lg++l+++s +lf+++ + C++ w++++gf+l f+++++Ktwr+++ FUN_001130-T1 484 ILFWFAFTTSTLGVIMAVIFLIFNIYHQNVRYIKMSSPNLNNLIILGCILVYVSGILFGLDKGvyCTGCQVEIWFLAIGFSLGFGAMFSKTWRVHV 579 567778899****************************************************8843445**************************** PP 7tm_3 100 ifkarkpglrkkkisdkqllllvlllllvqviiliiwlldsppkpek.........dtss...keeiileC.essstaflylvlgykglLlllgff 182 if + ++ ++ i+d+ql+ +v++lll++ iil++w+l++p+++++ d + ++ + +C + ++++++ +++gykglLll+g++ FUN_001130-T1 580 IFLKCNN-NKRVIIRDHQLFGMVAVLLLIDFIILTTWQLVDPLTTRDynltleispD--YdtaIQRFTTTCtSKHISIWQAIMFGYKGLLLLFGAY 672 **65544.44444*************************9889999986666655442..143449999***555599******************* PP 7tm_3 183 lafktrklp.dnfneakfitfsmllfllvwiifiplyllstkgkyqdav.aveifailasstvllllifvPK 252 l+++trk++ ++n++k i++s++++++ ++ +ip+ l+ + + ++ a+ +f +++++t++l+++fvPK FUN_001130-T1 673 LTWETRKVHiPALNDSKMIGLSVYNVIIPCALVIPIVGLVHDRPT--TQfALTSFLTIFCTTFTLCFVFVPK 742 ***********************************8854334333..477*********************9 PP >> ANF_receptor Receptor family ligand binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 188.9 0.0 2.1e-59 1.8e-55 4 352 .. 82 436 .. 80 437 .. 0.82 Alignments for each domain: == domain 1 score: 188.9 bits; conditional E-value: 2.1e-59 ANF_receptor 4 lAvrlAvedinsdpsllpgtkleviildtccdpslaleaaldllkg.e.vaaiiGpssssvasavaslanefkvpvisygstspelsdknryptfl 97 +Av++A++din++++ l+++ le+ i+d++c++ a + +l+ + + + ++Gp++s ++++va+ ++++ +i+++ +sp ls+k+ yp + FUN_001130-T1 82 PAVQMAIDDINNSSKCLKDYHLELLIKDSQCSVGEAIRRSLEYISYgKpKIMFLGPGCSKASIPVAEAIHYWNIVQIGFSGSSPLLSSKSLYPLYF 177 79******************************************9855666899****************************************** PP ANF_receptor 98 rtvpsdtsqakAiadilkhfgWkrvaliysdddygesglqaleealrergirvalkavippsqddd.eivrkllkevkskearvivlcasseearr 192 rt ps t+ + ++il+ f+Wkrva++ +++d ++ + l+e l++ ++ v + ++++ d+ ++++l+ ++ +ar+i +++++++ + FUN_001130-T1 178 RTNPSETFANLGRIAILRRFNWKRVAILQQNNDVFTGISNSLVELLEAANFSVIAYESFK---DHPrFAIENLK---NK-DARIIFAFFYPDQYYV 266 ******************************************************999999...44425555554...66.9*************** PP ANF_receptor 193 llkaarelgmmgeeyvwi......atdglttslvidkps...dlttleaaegvlgfrl.....hepespe..fsefvekeklskekenyenlgklq 272 +++a+++gm g +yvw+ +++ ++++ + + + + ++ + l + p++++ +e + ++ + ++++++ FUN_001130-T1 267 TFCEAYKQGMYGPKYVWVlfsgrnQANWWKQQSHFGDCTpeqV--RKGLSNNIGTGELklsplPGPTICGrtPQELY------NSYQLRLKESGYS 354 ******************6666665555555555555447552..33333333333332233422222221123333......3345566677777 PP ANF_receptor 273 vsyalaa.YDavyllAhAleellrkd.ksgs.lacgalkpwnggqsllrylknvnfkGltGevqfdengdrinpdydilnlkg 352 ++++ YDa ++ A l+ + +++ l+ + ++ n +++++ +k ++f G+tG+v+fd+n dri +++++ +++g FUN_001130-T1 355 ENTFASYgYDAAWACALTLNASIEVLrQQNLtLSDFTYSQANMSKTFVEIMKGISFRGMTGQVKFDSNYDRI-SKLEVRQIQG 436 78888888*************997666444456666667999999***************************.****999887 PP >> Peripla_BP_6 Periplasmic binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 8.9e-09 7.6e-05 16 214 .. 75 275 .. 59 429 .. 0.84 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 8.9e-09 Peripla_BP_6 16 ssgkssragaklaveeiNaaGGin.GrkielvvaDdqgdpdtaaaaarklvdqegvdaii.gglssavalavaevlakkgvpvigpsgltgekcsp 109 s+ + ++++a+++iN+ +++ + +el+++D q ++ +a ++ + ++ ++ ++++ g+ s ++ vae++ +++ ig+sg+++ s+ FUN_001130-T1 75 WSSAGIIPAVQMAIDDINNSSKCLkDYHLELLIKDSQCSVGEAIRRSLEYISYGKPKIMFlGPGCSKASIPVAEAIHYWNIVQIGFSGSSPLLSSK 170 556677789**********99999899*************************99987655155557777888888888999999999888865555 PP Peripla_BP_6 110 nvf..slgpttsaqaaalvdyla.kelggkkvaligadyafgraleaaakaalkaaGgkvvgevrvplgttDfssvvlqikasgadavllalagad 202 + +++ ++s + a l++ ++ + + k+va++++++ + + +++ + l+aa ++v++ + ++ + + + +k+++a ++++++++++ FUN_001130-T1 171 SLYplYFRTNPSETFANLGRIAIlRRFNWKRVAILQQNNDVFTGISNSLVELLEAANFSVIAYESFK---DHPRFAIENLKNKDARIIFAFFYPDQ 263 5551144557778888888865557899********************************9766666...66677888999999999999999887 PP Peripla_BP_6 203 avnllkqaaeaG 214 + +a ++G FUN_001130-T1 264 YYVTFCEAYKQG 275 644444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (789 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1001 (0.0391858); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7472.43 // Query: FUN_001131-T1 [L=121] Description: FUN_001131 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 605 (0.0236837); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1202.76 // Query: FUN_001132-T1 [L=225] Description: FUN_001132 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (225 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 614 (0.024036); expected 510.9 (0.02) Passed bias filter: 333 (0.0130358); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2261.81 // Query: FUN_001133-T1 [L=205] Description: FUN_001133 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-42 144.1 0.5 8.5e-24 84.7 0.0 2.4 2 Astacin Astacin (Peptidase family M12A) ------ inclusion threshold ------ 0.15 13.0 0.4 0.24 12.4 0.4 1.3 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like Domain annotation for each model (and alignments): >> Astacin Astacin (Peptidase family M12A) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.7 0.0 6.7e-28 8.5e-24 16 90 .. 56 130 .. 31 134 .. 0.81 2 ! 58.2 0.1 9.2e-20 1.2e-15 116 186 .] 132 199 .. 131 199 .. 0.96 Alignments for each domain: == domain 1 score: 84.7 bits; conditional E-value: 6.7e-28 Astacin 16 eekeraaiakaleeyekktCikfkereaseenylkvtkgegClSevGra.ggkqevslgkgCeklgiivHElgHal 90 ++ +++ai +a++e+e+ktCi+f++r+ s+++y++++ g+gC+S+vG+ +gkq++s+g+gC gi+ HE+gHal FUN_001133-T1 56 KGPTERAIFSAIKEWEEKTCIRFVPRA-SHKDYVEFFAGDGCWSYVGDLmNGKQQISIGSGCFFHGIVLHEIGHAL 130 334678899******************.9*******************99*************************9 PP == domain 2 score: 58.2 bits; conditional E-value: 9.2e-20 Astacin 116 qeenfekvdskevdslgvpYdygSimhYakkafskngaleTivpkkeelqktiGqreklsevDikkinklY 186 ++nf+k+ + ++dsl+v YdygSimhY+k f+k ++ Ti++k+ + iGqr++ls++D++++n Y FUN_001133-T1 132 NKHNFNKYGHGSIDSLDVRYDYGSIMHYGKRDFAKWPWQTTIKTKHG---ESIGQRRHLSSLDVTQMNLYY 199 579***************************************99988...79****************988 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.4 1.9e-05 0.24 81 122 .. 98 134 .. 75 135 .. 0.74 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.9e-05 Reprolysin_3 81 AyvgavcnsskkfglnsgssplgdtgadtfaHEiGHnfGanH 122 yvg ++n ++++++ sg+ + + + HEiGH + +H FUN_001133-T1 98 SYVGDLMNGKQQISIGSGC-----FFHGIVLHEIGHALENKH 134 4666666666666666555.....5689*********99988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (205 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 577 (0.0225876); expected 510.9 (0.02) Passed bias filter: 516 (0.0201996); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.43s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2006.40 // Query: FUN_001134-T1 [L=387] Description: FUN_001134 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-36 126.4 27.7 2.1e-34 119.7 27.7 2.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 2.1e-08 34.4 19.9 4.5e-08 33.3 19.9 1.5 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 3.7 8.7 9.8 0.71 11.0 0.4 2.9 3 NADH-u_ox-rdase NADH-ubiquinone oxidoreductase complex I, 21 Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 119.7 27.7 2.5e-38 2.1e-34 2 260 .] 102 337 .. 101 337 .. 0.89 Alignments for each domain: == domain 1 score: 119.7 bits; conditional E-value: 2.5e-38 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalv....yallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplky 93 NllV+++++ n klrt+tn+f+l LavaD+lv+++++p++++ ya+ ++++ f++v ++ +d +++++sil+l+ais++RY ++ ++++ FUN_001134-T1 102 NLLVVTAFFINEKLRTVTNYFVLGLAVADILVGAISVPLWMYilksYASSTRGKNFKYVE-MFYRTMDGFAGISSILHLMAISMERYFCVGWAVRH 196 ****************************************95333255566778887775.89999999*************************** PP xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrral.vlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkek 188 ++t+++++ + +++vW++++l++++ l++ + + ++++ll+sv++fllpl++i++ y+ i++ ++ + +++ FUN_001134-T1 197 --RNTPKHVYyIALFLVWLFSALAACIKLMIPKI--------------EA--------KEFALLTSVVFFLLPLTIIVIAYAAIWKIAMTRMNNNP 268 ..55776665166789**************7643..............33........3599*******************************999 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 189 skkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 s k+s ++e +++ t++ v+v+f+++w+P+f+++++ ++ + + + ++ a++++ +l y+ns +NPi+Y FUN_001134-T1 269 S--KRSLKREIRTAATIAFVIVFFLVAWTPFFVTFVIVAY-CPPSVCPFNWSATIFYKFLHYSNSSINPIVY 337 9..66788999***********************999998.7778888888899*****************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 19.9 5.3e-12 4.5e-08 2 254 .. 96 349 .. 95 352 .. 0.80 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 5.3e-12 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltgt.qlkreeCFlli..ivyvf..gltaqsvl.lLvigiDlliavk 91 vv +++N+l++ ++f ++kLr+ +++ + +++ad+l+ +++ + l+ + +++r + F ++ ++ ++ ++ ++s+l l++i + + ++v FUN_001134-T1 96 VVAVFSNLLVVTAFFINEKLRTVTNYFVLGLAVADILVGAISVPLWMYILKSYaSSTRGKNFKYVemFYRTMdgFAGISSILhLMAISMERYFCVG 191 899*************************************999999999876525677777776521333322255566777256799******** PP 7TM_GPCR_Srsx 92 fPirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkke.kkkssskkvl 186 +r+r+ +k+ Y+++ l+++ l+s+++ ++ + e a +al ++ +f l ii ++ ++ +++ ++++ + ++ ++ ++ FUN_001134-T1 192 WAVRHRNTPKHVYYIA-LFLVWLFSALAACIKLMIPKIE-----AKEFAL-LTSVVFFLLPLTIIVIAYAAIWKIAMTRMNNNPSkRSLKREIRTA 280 ***********99865.678999****999999988888.....778898.677778888888888888888888877776665404567788899 PP 7TM_GPCR_Srsx 187 kslkvtvvififgWftstilntvllaltes.eevekliqayagilvllsfsqnffVtywrsseYrkafr 254 +++++v+f++ W+ + + ++ + + s ++ + +l ++s n +V+ +r +e+rk+ + FUN_001134-T1 281 ATIAFVIVFFLVAWTPFFVTFVIVAYCPPSvCPFNWSATIFYKFLHYSNSSINPIVYGVRIPEFRKTSK 349 99************97777776666665551566667888899999*******************9865 PP >> NADH-u_ox-rdase NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.3 3 2.6e+04 25 33 .. 91 99 .. 82 110 .. 0.57 2 ? 11.0 0.4 8.4e-05 0.71 28 82 .. 131 187 .. 113 193 .. 0.81 3 ? 3.5 0.2 0.018 1.6e+02 28 73 .. 250 291 .. 239 296 .. 0.65 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 3 NADH-u_ox-rdase 25 yavwaavta 33 ya++a+v++ FUN_001134-T1 91 YAIIAVVAV 99 444444433 PP == domain 2 score: 11.0 bits; conditional E-value: 8.4e-05 NADH-u_ox-rdase 28 waavtaafpagllvweklspskagkaslapa.lrlagllGfig..gfllayqrSslRl 82 +++ ++++p+ +++++++++s +gk+ ++ + +++ ++ Gf g ++l + S+ R FUN_001134-T1 131 ILVGAISVPLWMYILKSYASSTRGKN-FKYVeMFYRTMDGFAGisSILHLMAISMERY 187 4556669************9998886.5555599999999999867788888888886 PP == domain 3 score: 3.5 bits; conditional E-value: 0.018 NADH-u_ox-rdase 28 waavtaafpagllvweklspskagkaslapalrlagllGfiggfll 73 ++a++a++ ++++ ++ +psk+ sl++ +r+a++++f+ f+l FUN_001134-T1 250 VIAYAAIWKIAMTRMN-NNPSKR---SLKREIRTAATIAFVIVFFL 291 3444455555555543.345553...56778999999999986655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (387 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1405 (0.055001); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 3732.42 // Query: FUN_001135-T1 [L=338] Description: FUN_001135 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-37 128.7 26.4 4.8e-35 121.8 26.4 2.2 1 7tm_1 7 transmembrane receptor (rhodopsin fami 1.4e-09 38.2 19.3 2.7e-09 37.3 19.3 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor S ------ inclusion threshold ------ 0.053 14.6 9.0 0.64 11.2 0.6 2.9 3 NADH-u_ox-rdase NADH-ubiquinone oxidoreductase complex I 0.25 10.6 0.2 0.32 10.3 0.2 1.1 1 Beta-prop_WDR35_2nd WDR35 second beta-propeller 1.5 9.8 8.1 1.3 10.1 1.6 2.9 3 DUF3681 Protein of unknown function (DUF3681) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 121.8 26.4 9.4e-39 4.8e-35 1 260 [] 52 288 .. 52 288 .. 0.89 Alignments for each domain: == domain 1 score: 121.8 bits; conditional E-value: 9.4e-39 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalv....yallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gNllV+++++ n klrt+tn+f+l LavaD+lv+++++p++++ ya+ ++++ f++v ++ +d +++++sil+l+ais++RY ++ ++++ FUN_001135-T1 52 GNLLVVTAFFINDKLRTVTNYFVLGLAVADILVGAISVPLWMYilksYASSTRGKNFKYVE-MFYRTMDGFAGISSILHLMAISMERYFCVGWAVR 146 8****************************************95333255566778887775.89999999************************** PP xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrral.vlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakke 187 ++t+++++ + +++vW++++l++++ l++ + + ++++ll+sv++fllpl++i++ y+ i++ ++ + +++ FUN_001135-T1 147 H--RNTPKHVYyIALFLVWLFSALAACIKLMIPKI--------------EA--------KELALLTSVVFFLLPLTIIVIAYAAIWKIAMTRMNNN 218 *..55776665166789**************7643..............33........3599*******************************99 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 188 kskkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 s k+s ++e ++++t++ v+++f+++w+P+f+++++ ++ + ++ + ++ a++++ +l y+ns +NPi+Y FUN_001135-T1 219 PS--KRSLKREIRTATTIAFVIGFFLVAWTPFFVTFVIVAY-CPSSVCPFNWSATIFYKVLHYSNSSINPIVY 288 99..66788999************************99998.7777788888899*****************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.3 19.3 5.3e-13 2.7e-09 2 255 .. 47 301 .. 46 303 .. 0.80 Alignments for each domain: == domain 1 score: 37.3 bits; conditional E-value: 5.3e-13 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltgt.qlkreeCFlli..ivyvf..gltaqsvl.lLvigiDlliavk 91 +v ++GN+l++ ++f + kLr+ +++ + +++ad+l+ +++ + l+ + +++r + F ++ ++ ++ ++ ++s+l l++i + + ++v FUN_001135-T1 47 LVAVFGNLLVVTAFFINDKLRTVTNYFVLGLAVADILVGAISVPLWMYILKSYaSSTRGKNFKYVemFYRTMdgFAGISSILhLMAISMERYFCVG 142 6899************************************999999999876525677777776521333322255566777256799******** PP 7TM_GPCR_Srsx 92 fPirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkke.kkkssskkvl 186 +r+r+ +k+ Y+++ l+++ l+s+++ ++ + e a lal ++ +f l ii ++ ++ +++ ++++ + ++ ++ ++ FUN_001135-T1 143 WAVRHRNTPKHVYYIA-LFLVWLFSALAACIKLMIPKIE-----AKELAL-LTSVVFFLLPLTIIVIAYAAIWKIAMTRMNNNPSkRSLKREIRTA 231 ***********99865.678999***9999999988888.....778888.677778888888888888888888887776665404667888899 PP 7TM_GPCR_Srsx 187 kslkvtvvififgWftstilntvllaltese.evekliqayagilvllsfsqnffVtywrsseYrkafre 255 +++++ +f++ W+ + + ++ + ++s ++ + +l ++s n +V+ +r +e+rk+f+ FUN_001135-T1 232 TTIAFVIGFFLVAWTPFFVTFVIVAYCPSSVcPFNWSATIFYKVLHYSNSSINPIVYGVRIPEFRKTFKF 301 99************99988888888888876244445667777888999999***************985 PP >> NADH-u_ox-rdase NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.2 4.1 2.1e+04 25 33 .. 42 50 .. 28 59 .. 0.56 2 ? 11.2 0.6 0.00013 0.64 28 82 .. 82 138 .. 65 144 .. 0.81 3 ? 8.6 0.1 0.00081 4.1 28 74 .. 201 243 .. 195 246 .. 0.67 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 4.1 NADH-u_ox-rdase 25 yavwaavta 33 ya++a+v++ FUN_001135-T1 42 YAIIALVAV 50 334444433 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00013 NADH-u_ox-rdase 28 waavtaafpagllvweklspskagkaslapa.lrlagllGfig..gfllayqrSslRl 82 +++ ++++p+ +++++++++s +gk+ ++ + +++ ++ Gf g ++l + S+ R FUN_001135-T1 82 ILVGAISVPLWMYILKSYASSTRGKN-FKYVeMFYRTMDGFAGisSILHLMAISMERY 138 4556669************9998886.5555599999999999867788888888886 PP == domain 3 score: 8.6 bits; conditional E-value: 0.00081 NADH-u_ox-rdase 28 waavtaafpagllvweklspskagkaslapalrlagllGfiggflla 74 ++a++a++ ++++ ++ +psk+ sl++ +r+a++++f+ gf+l+ FUN_001135-T1 201 VIAYAAIWKIAMTRMN-NNPSKR---SLKREIRTATTIAFVIGFFLV 243 4445555555555553.345553...677889**********99875 PP >> Beta-prop_WDR35_2nd WDR35 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.2 6.2e-05 0.32 12 129 .. 102 224 .. 92 234 .. 0.80 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 6.2e-05 Beta-prop_WDR35_2nd 12 yekperkeecvvFwdtknnekyvkyvksllaiaaagdycv.latkaeeeeee....aqyvlvlcnaigtpvdskyidleplfvamtkshv 96 +++ ++ +++ +F+ t + + + +l+ai+ +cv a+++ ++ ++ a +++ l+ a+++ + ++e++ +a+ +s v FUN_001135-T1 102 STRGKNFKYVEMFYRTMDGFAGISSILHLMAISMERYFCVgWAVRHRNTPKHvyyiALFLVWLFSALAACIKLMIPKIEAKELALLTSVV 191 344555566669****************************4345555443334566789999**************************** PP Beta-prop_WDR35_2nd 97 vvaskeafyvWqyrtpkklsalelskvlkskke 129 ++ +++v y + k++ ++++++ ++++ FUN_001135-T1 192 FFLLPLTIIVIAYAAIWKIAMTRMNNNPSKRSL 224 **************9999999999877655544 PP >> DUF3681 Protein of unknown function (DUF3681) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 1.6 0.00025 1.3 33 88 .. 31 84 .. 3 88 .. 0.74 2 ? 1.8 0.1 0.093 4.7e+02 33 67 .. 61 98 .. 57 111 .. 0.63 3 ? 2.5 0.3 0.055 2.8e+02 33 63 .. 145 175 .. 119 203 .. 0.77 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00025 DUF3681 33 flrgkallyayygilvavvlfGvaevavglwvsgdperRravGktvlwvsvvplvl 88 + + + ++ +y i++ v++fG v +++++++ R ++ vl ++v +++ FUN_001135-T1 31 SMDSVMAAWFFYAIIALVAVFGNLLVVTAFFINDKL--RTVTNYFVLGLAVADILV 84 3455668999**********************9876..777777777777776665 PP == domain 2 score: 1.8 bits; conditional E-value: 0.093 DUF3681 33 flrgkallyayygil...vavvlfGvaevavglwvsgd 67 f ++k+ +++ y +l va +l+G++ v + +++ ++ FUN_001135-T1 61 FINDKLRTVTNYFVLglaVADILVGAISVPLWMYILKS 98 56666655555555422255679999999988888766 PP == domain 3 score: 2.5 bits; conditional E-value: 0.055 DUF3681 33 flrgkallyayygilvavvlfGvaevavglw 63 + + +++ +yy++l v lf + + + l FUN_001135-T1 145 VRHRNTPKHVYYIALFLVWLFSALAACIKLM 175 457888999***********99888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (338 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1508 (0.0590331); expected 510.9 (0.02) Passed bias filter: 587 (0.0229791); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.43 # Mc/sec: 3196.63 // Query: FUN_001136-T1 [L=327] Description: FUN_001136 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-44 153.4 21.9 1.8e-24 87.1 6.8 2.3 3 7tm_1 7 transmembrane receptor (rhodopsin family) 2.3e-12 47.3 16.4 6.8e-10 39.3 16.4 2.2 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.5 0.6 1.3 1.6e+04 168 176 .. 23 31 .. 18 36 .. 0.38 2 ! 87.1 6.8 1.4e-28 1.8e-24 1 118 [. 38 153 .. 38 166 .. 0.92 3 ! 79.8 7.1 2.5e-26 3.2e-22 137 260 .] 151 272 .. 148 272 .. 0.91 Alignments for each domain: == domain 1 score: -4.5 bits; conditional E-value: 1.3 xxxxxxxxx RF 7tm_1 168 vilvcyvri 176 v +++yv i FUN_001136-T1 23 VSCFFYVII 31 222222222 PP == domain 2 score: 87.1 bits; conditional E-value: 1.4e-28 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN+lVi ++r+ +lrt tn+f+++LavaD++v+++++p++++ l+ ++ +gev+ ++++ld++++t+sil+l++is++R+ a+v+p++ ++ FUN_001136-T1 38 GNGLVIGSFIRYYRLRTITNYFVVSLAVADIIVGVISIPIWISILLY-SSAEIGEVVNTVYNVLDLFAGTSSILHLVVISMERFFAVVYPIQHRN- 131 8*****************************************99996.*********************************************66. PP xxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 97 rtkrralvlilvvWvlalllsl 118 ++ ++ v++++vWv+ ++++ FUN_001136-T1 132 TSTKVYNVFLIAVWVIPAVACG 153 77789999999****9887765 PP == domain 3 score: 79.8 bits; conditional E-value: 2.5e-26 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 137 vClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkec 232 C +++ ++t+++ +l+l++ +f++pl+vil y+ri++t++ + + +++ ++ ++++ +++ t+++v+++fv++wlP+f+++ll +++++c FUN_001136-T1 151 ACGSSIEL-KKTSREANMLFLFITFFVVPLFVILSAYARIWHTASTRIQPLQQS-SRTMKRDMRIAFTIALVIGFFVIAWLPFFTVQLLLVFCHQC 244 68888877.5567888888899999999**********************9985.55668889********************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 233 eseklvetallitlllayvnsclNPiiY 260 + e ++ +ll++ ++ y+ns++NPiiY FUN_001136-T1 245 QPEIYSKGLLLFVKFMHYSNSAVNPIIY 272 **************************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 16.4 5.3e-14 6.8e-10 2 256 .. 33 286 .. 32 287 .. 0.71 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 5.3e-14 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltgtqlk.reeCFlliivyvfgltaqsvl.lLvigiDlliavkfPir 95 ++ ++GN l+i +++ +Lr+ +++ ++ +++ad+++ v +++ ++ l + + e ++ v +++ ++s+l l+vi + +++av +Pi+ FUN_001136-T1 33 FLAVFGNGLVIGSFIRYYRLRTITNYFVVSLAVADIIVGVISIPIWISILLYSSAEiGEVVNTVYNVLDLFAGTSSILhLVVISMERFFAVVYPIQ 128 6899***************************************99997663333331333333333444455555555166799************ PP 7TM_GPCR_Srsx 96 YrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek............kk 179 +r+ s++ Y ++l+++ v+ ++ +C + l+++++e +++ l+i +v+ ++++l ++ +++ ++ FUN_001136-T1 129 HRNTSTKVYNVFLIAVWVIPAV----------------ACGSSIELKKTSRE-ANMLFLFITFFVVPLFVILSAYARIWHTAstriqplqqssrTM 207 *******887777666666554................45555555444333.3444455555555555444444333222223344333323355 PP 7TM_GPCR_Srsx 180 ssskkvlkslkvtvvififgW..ftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 ++ ++ +++++ +f++ W f++ l v+++ + e ++k + + + ++ +++ n +++ ++ +e+r+a+++l FUN_001136-T1 208 KRDMRIAFTIALVIGFFVIAWlpFFTVQLLLVFCHQCQPEIYSKGLLLFVKFMHYSNSAVNPIIYAIKIPEFRRAYKQL 286 5555666689999********665777777888888888899999*******************************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (327 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1558 (0.0609904); expected 510.9 (0.02) Passed bias filter: 610 (0.0238794); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 3213.84 // Query: FUN_001137-T1 [L=605] Description: FUN_001137 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-213 710.9 35.8 1.5e-213 710.7 35.8 1.0 1 SNF Sodium:neurotransmitter symporter family ------ inclusion threshold ------ 0.26 12.0 0.2 0.57 10.9 0.2 1.5 1 MJ0548_C Connectase MJ0548-like, C-terminal domain Domain annotation for each model (and alignments): >> SNF Sodium:neurotransmitter symporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 710.7 35.8 1.2e-217 1.5e-213 1 521 [. 43 565 .. 43 568 .. 0.98 Alignments for each domain: == domain 1 score: 710.7 bits; conditional E-value: 1.2e-217 SNF 1 RetwskkldfllsvvGfavgLgnvWRFPYlcyknGGGafliPYlilllvaGiPlfflelalGqytreGaitvwrkicPlfkgiGyasivialyvgl 96 Re+w+kk+df+ls++G+avgLgnvWRFPYlcy+nGG +fliPY+i+l + GiPlf++ela+Gqy + G++++w +cP+ +giG+ +i+++++v++ FUN_001137-T1 43 REKWGKKIDFMLSCIGYAVGLGNVWRFPYLCYENGGATFLIPYFIMLAINGIPLFYMELAIGQYLSLGTVGAWTALCPIARGIGFGMIMVSFLVSI 138 9*********************************************************************************************** PP SNF 97 yYnvilawalyYlfssftteLpWaeCnnswnteeCvealakenssaass.enlt.ektspaeefferkvlklskgieelGelrwelalcllvalvv 190 yYn+i+aw l Ylf+sf +++pW++C+n+wnt+ C e++++++ + ++ + ++tsp+eeff++++lk++++i+++G+++w+++lcl++a+v+ FUN_001137-T1 139 YYNLIIAWCLLYLFESFRKDVPWKNCGNNWNTPLCSETTERADFNCSAIgLAVGcKTTSPSEEFFNHYILKITDSISDMGSVSWQIVLCLILAWVI 234 *************************************999999874433133336899************************************** PP SNF 191 vylsilkGvkssgkvvyftatfPyvvllvllvrgvtLpGavkgikfyltpdlekllepkvWidaatqiffslgigfGvlialasYnkfennvyrda 286 vyl+++kGv+ssgkvvyftatfPyvvl++l++rg tL+G+++g+ fyl+pd++kl++p+vW+ aa+qif+slg+gfG+li+++sYnkf+nn+ rda FUN_001137-T1 235 VYLCLIKGVASSGKVVYFTATFPYVVLFILMIRGATLEGSLDGVLFYLKPDVSKLKDPRVWVRAASQIFYSLGVGFGSLITFGSYNKFNNNCERDA 330 ************************************************************************************************ PP SNF 287 llvslinsltsvlagfviFsvlGfmaqeqgveisevaeeGpgLaFiaypeavtklplsplwsvlFFlmllllgldsqfavveglitalvDefkvll 382 ++vs++n+ ts++agfv+FsvlGfmaq+ +ve+ +v ++GpgLaF+ ypea++++p+s+lw++lFF+mll+lgldsqfa+ve+++t+l De++++l FUN_001137-T1 331 IIVSCVNCGTSFFAGFVVFSVLGFMAQTLKVEVGDVVTSGPGLAFVGYPEAIAQMPVSTLWAILFFFMLLTLGLDSQFAMVECVVTGLSDEYPKYL 426 ************************************************************************************************ PP SNF 383 rkrrellvlivvvlaflvglllvtegGiyvlelldkyaaslsllvvalleaiavawvyglkrflddikemlgfrpglflklcwklvspllllalli 478 r+ + ++ + v+vl+fl+++ ++++gG+yv++l+d + ++sll++ ++ea ++ w g++ + d i++m+g rp +f+ +cwk++spl l+++i FUN_001137-T1 427 RRYKPFFLIGVCVLMFLLAIPMCSQGGMYVFNLFDMQSGGISLLFIGFCEAAVIGWGVGTQTLGDMIEKMIGKRPNIFFLICWKYLSPLATLVIII 522 ************************************************************************************************ PP SNF 479 asivkykpltyekyvyPkwaealgwllalssvvviplvvilkl 521 as++++ ++y+k yP wae +gwllal+s+v++p++vi+++ FUN_001137-T1 523 ASLAQWGGISYDKKPYPGWAEFFGWLLALASMVMVPIFVIVQC 565 ***************************************9976 PP >> MJ0548_C Connectase MJ0548-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.2 4.4e-05 0.57 44 81 .. 9 44 .. 3 57 .. 0.77 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 4.4e-05 MJ0548_C 44 qAldlekkvapgekvlmeieeegdvkeGdivvienenL 81 A d +k ++++ + + e+ +v+eGd+vvie+e+ FUN_001137-T1 9 SASD--EKAEKPQGSHVAFVEQMTVEEGDVVVIEEERE 44 5556..67777777778888999************975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (605 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1155 (0.0452143); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.41s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 5918.69 // Query: FUN_001139-T1 [L=609] Description: FUN_001139 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.7e-213 708.2 30.3 1e-212 708.1 30.3 1.0 1 SNF Sodium:neurotransmitter symporter family Domain annotation for each model (and alignments): >> SNF Sodium:neurotransmitter symporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 708.1 30.3 3.9e-217 1e-212 1 523 [. 47 571 .. 47 572 .. 0.97 Alignments for each domain: == domain 1 score: 708.1 bits; conditional E-value: 3.9e-217 SNF 1 RetwskkldfllsvvGfavgLgnvWRFPYlcyknGGGafliPYlilllvaGiPlfflelalGqytreGaitvwrkicPlfkgiGyasivialyvgl 96 Re+w++kldflls++G+avgLgnvWRFPYlcy+nGG +fliPY+i+l+++GiP+f+le+alGqy +G +++w icP++ giG+ +++i++++++ FUN_001139-T1 47 REHWGRKLDFLLSCIGYAVGLGNVWRFPYLCYNNGGASFLIPYIICLVFCGIPIFYLEVALGQYVGQGVVGAWAAICPFLGGIGLGMVIITFLCSV 142 9*********************************************************************************************** PP SNF 97 yYnvilawalyYlfssftteLpWaeCnnswnteeCvealakenssaassenlt...ektspaeefferkvlklskgieelGelrwelalcllvalv 189 yYnvi+aw++yY+f+sf ++LpW++C++ w t+ C +++ + ++ + + +l + +sp e++f+++vlk+s gi++ Ge+r+ela+cll+ ++ FUN_001139-T1 143 YYNVIIAWTFYYMFASFRKQLPWEHCSEPWMTNLCKSDRGNISQPNCTLLKLPsdcKWVSPEEDYFNNHVLKISPGIDDAGEVRFELAMCLLLGWI 238 ***********************************887655444444433333333889************************************* PP SNF 190 vvylsilkGvkssgkvvyftatfPyvvllvllvrgvtLpGavkgikfyltpdlekllepkvWidaatqiffslgigfGvlialasYnkfennvyrd 285 +vy++++kG+ks+gkvvyftatfPy+vl++ll+rg tL+Ga +g+ fyl+p++ekl++pkvW+daa qiffsl+igfG+li+++sYnkf nn+ +d FUN_001139-T1 239 IVYFCVWKGIKSAGKVVYFTATFPYLVLFILLIRGATLEGAGEGVLFYLKPKFEKLKNPKVWVDAAGQIFFSLSIGFGGLITYGSYNKFRNNCEKD 334 ************************************************************************************************ PP SNF 286 allvslinsltsvlagfviFsvlGfmaqeqgveisevaeeGpgLaFiaypeavtklplsplwsvlFFlmllllgldsqfavveglitalvDefkvl 381 +l+vslin+ ts++agfviF+++Gfm+++ gv++++v + G+gLaFiaype + ++p+sp+w+++FF+ml +lgldsqf++ve+ t l+D + FUN_001139-T1 335 TLIVSLINCGTSLFAGFVIFTMMGFMSHKLGVDVEDVVKGGAGLAFIAYPEGIKQMPASPFWAFIFFFMLFNLGLDSQFVGVETCTTVLADWKPG- 429 *******************************************************************************************9998. PP SNF 382 lrkrrellvlivvvlaflvglllvtegGiyvlelldkyaaslsllvvalleaiavawvyglkrflddikemlgfrpglflklcwklvspllllall 477 +r+ + +++l ++l++l+gl+ vt+gG+yv++++d+ a ++sl+++alle++++ w+yg+++f+ di++m+g+rp +++++cwk++sp ++ +++ FUN_001139-T1 430 FRRYKAVITLGFCILCYLLGLAHVTRGGMYVFQMFDYQAGGISLVLIALLEVLGIGWFYGIEQFSTDIENMIGHRPNMYFRICWKYLSPGIIGVIF 525 6779******************************************************************************************** PP SNF 478 iasivkykpltyekyvyPkwaealgwllalssvvviplvvilklls 523 i + v ++ ++y y+yP wae lgw+l ++s++++p +++ ++l+ FUN_001139-T1 526 IWFCVDWSGISYAGYQYPPWAEFLGWMLCIVSLLCVPGYALHRYLK 571 ***************************************9988775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (609 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 796 (0.0311607); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.43 # Mc/sec: 5726.52 // Query: FUN_001139-T2 [L=467] Description: FUN_001139 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-175 583.5 19.4 6.6e-175 583.2 19.4 1.0 1 SNF Sodium:neurotransmitter symporter family Domain annotation for each model (and alignments): >> SNF Sodium:neurotransmitter symporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 583.2 19.4 2.6e-179 6.6e-175 1 407 [. 47 455 .. 47 458 .. 0.96 Alignments for each domain: == domain 1 score: 583.2 bits; conditional E-value: 2.6e-179 SNF 1 RetwskkldfllsvvGfavgLgnvWRFPYlcyknGGGafliPYlilllvaGiPlfflelalGqytreGaitvwrkicPlfkgiGyasivialyvgl 96 Re+w++kldflls++G+avgLgnvWRFPYlcy+nGG +fliPY+i+l+++GiP+f+le+alGqy +G +++w icP++ giG+ +++i++++++ FUN_001139-T2 47 REHWGRKLDFLLSCIGYAVGLGNVWRFPYLCYNNGGASFLIPYIICLVFCGIPIFYLEVALGQYVGQGVVGAWAAICPFLGGIGLGMVIITFLCSV 142 9*********************************************************************************************** PP SNF 97 yYnvilawalyYlfssftteLpWaeCnnswnteeCvealakenssaassenlt...ektspaeefferkvlklskgieelGelrwelalcllvalv 189 yYnvi+aw++yY+f+sf ++LpW++C++ w t+ C +++ + ++ + + +l + +sp e++f+++vlk+s gi++ Ge+r+ela+cll+ ++ FUN_001139-T2 143 YYNVIIAWTFYYMFASFRKQLPWEHCSEPWMTNLCKSDRGNISQPNCTLLKLPsdcKWVSPEEDYFNNHVLKISPGIDDAGEVRFELAMCLLLGWI 238 ***********************************887655444444433333333889************************************* PP SNF 190 vvylsilkGvkssgkvvyftatfPyvvllvllvrgvtLpGavkgikfyltpdlekllepkvWidaatqiffslgigfGvlialasYnkfennvyrd 285 +vy++++kG+ks+gkvvyftatfPy+vl++ll+rg tL+Ga +g+ fyl+p++ekl++pkvW+daa qiffsl+igfG+li+++sYnkf nn+ +d FUN_001139-T2 239 IVYFCVWKGIKSAGKVVYFTATFPYLVLFILLIRGATLEGAGEGVLFYLKPKFEKLKNPKVWVDAAGQIFFSLSIGFGGLITYGSYNKFRNNCEKD 334 ************************************************************************************************ PP SNF 286 allvslinsltsvlagfviFsvlGfmaqeqgveisevaeeGpgLaFiaypeavtklplsplwsvlFFlmllllgldsqfavveglitalvDefkvl 381 +l+vslin+ ts++agfviF+++Gfm+++ gv++++v + G+gLaFiaype + ++p+sp+w+++FF+ml +lgldsqf++ve+ t l+D + FUN_001139-T2 335 TLIVSLINCGTSLFAGFVIFTMMGFMSHKLGVDVEDVVKGGAGLAFIAYPEGIKQMPASPFWAFIFFFMLFNLGLDSQFVGVETCTTVLADWKPG- 429 *******************************************************************************************9998. PP SNF 382 lrkrrellvlivvvlaflvglllvte 407 +r+ + +++l ++l++l+gl+ vt+ FUN_001139-T2 430 FRRYKAVITLGFCILCYLLGLAHVTR 455 6779******************9996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (467 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 404 (0.0158152); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4614.78 // Query: FUN_001140-T1 [L=863] Description: FUN_001140 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-71 239.0 0.0 2.2e-40 138.8 0.0 3.0 3 PTPlike_phytase Inositol hexakisphosphate 5.2e-11 43.5 0.0 8.4e-05 23.5 0.0 2.7 2 Tc-R-P Polymorphic toxin system, DSP-PTPase phospha 9.5e-10 39.2 0.0 0.00021 21.9 0.0 2.4 2 PTP-SAK Swiss Army Knife protein, DSP-PTPase phospha 0.00028 21.1 0.0 0.1 12.7 0.0 2.3 2 Y_phosphatase Protein-tyrosine phosphatase ------ inclusion threshold ------ 0.035 14.1 0.2 0.072 13.1 0.2 1.4 1 Baculo_PP31 Baculovirus 33KDa late protein (PP31) 0.043 14.2 0.0 4.4 7.7 0.0 2.5 2 Y_phosphatase3 Tyrosine phosphatase family 0.25 11.2 0.0 22 4.9 0.0 2.6 2 PTP-NADK DSP-PTPase phosphatase fused to NAD+ Kinase Domain annotation for each model (and alignments): >> PTPlike_phytase Inositol hexakisphosphate # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.8 0.0 6e-44 2.2e-40 1 157 [. 142 310 .. 142 311 .. 0.95 2 ? -0.8 0.0 0.54 2e+03 117 141 .. 357 381 .. 351 382 .. 0.88 3 ! 96.5 0.0 6.5e-31 2.4e-27 1 157 [. 534 687 .. 534 688 .. 0.90 Alignments for each domain: == domain 1 score: 138.8 bits; conditional E-value: 6e-44 PTPlike_phytase 1 vnlReEpvv....yingrpyvlrekenllenlkeltgisaeeleklearlkkdvlaeakktggrvlvheetedgeevetvvevweevee..qtp 88 +nlReEpvv +++ py++r+++ l+ n+ +g+++eel++ e ++++++++ + ++gg++++++++e e+ + +v e e ++ FUN_001140-T1 142 FNLREEPVVfvglNHDYVPYSPRDPSSLKGNI-ANHGVKPEELADNELKIREEIIRLSIEEGGKFYFYNNVETLEDEPHPYKVVYE--EdlCVL 232 79*******999899****************9.99***************************************988887777554..356*** PP PTPlike_phytase 89 eevyeellaegpsvdYvRiPitdekapeeedfdalvsivketpe.........dtalvfnCqmGrgRTTtamviatLv 157 +e+y+++++ +p ++Y+RiPit+ +apee+dfd+++s++k+ + +a+vfnC++G+gRTTt+mvi++L+ FUN_001140-T1 233 DEIYSRQIFLTPFLRYSRIPITATNAPEEQDFDQFISAIKDILQlfdsnssapLPAMVFNCHVGQGRTTTGMVIGCLI 310 ******************************************777********************************9 PP == domain 2 score: -0.8 bits; conditional E-value: 0.54 PTPlike_phytase 117 eedfdalvsivketpedtalvfnCq 141 ++++d++++i++++++ ++++ C+ FUN_001140-T1 357 KQEVDSVIDICSDVMNLRSVIYVCK 381 689***********99999999996 PP == domain 3 score: 96.5 bits; conditional E-value: 6.5e-31 PTPlike_phytase 1 vnlReEpvvyingrpyvlrekenllenlkeltgisaeeleklearlkkdvlaeakktggrvlvheetedgeevetvvevweeveeqtpeevyee 94 +nlRe+ v ++g ++ re +n++e + g ++ e+ek e++lk+++l++ kk +v+ ++ +++ e + + t +e e FUN_001140-T1 534 FNLREDLAVDCDGSTFGSREISNVTEHM-PFRGLDTVEIEKKESDLKSELLRKGKKRPTKVY-KDVNRSPE-EQGFGSI------LTLRESAEL 618 79*************************9.9************************99999998.34444332.2222223......688999*** PP PTPlike_phytase 95 llaegpsvdYvRiPitdekapeeedfdalvsivketpe......dtalvfnCqmGrgRTTtamviatLv 157 +a++p+ Y+R+Pi++++apee+dfd ++si+ ++ e +a+vf+C+ G+gRTTt+m+ia L+ FUN_001140-T1 619 CMAKNPQTLYFRLPISEDRAPEEKDFDRILSILNNLHEiyadedGPAIVFSCESGKGRTTTGMAIAALI 687 ************************************888****************************98 PP >> Tc-R-P Polymorphic toxin system, DSP-PTPase phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 2.8e-06 0.01 47 104 .. 246 313 .. 228 315 .. 0.75 2 ! 23.5 0.0 2.3e-08 8.4e-05 11 99 .. 593 683 .. 585 690 .. 0.75 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 2.8e-06 Tc-R-P 47 llvlhvpikDlsaPsekqveeivrlidall...dndk..g...vvvHCraGvGRt..GtvlAsyLvrt 104 l + ++pi ++aP e+ ++++ i+++l d++ + +v C+ G GRt G v+ + ++ + FUN_001140-T1 246 LRYSRIPITATNAPEEQDFDQFISAIKDILqlfDSNSsaPlpaMVFNCHVGQGRTttGMVIGCLIISH 313 56789******************999987644444432233336889*******73366788877765 PP == domain 2 score: 23.5 bits; conditional E-value: 2.3e-08 Tc-R-P 11 aikddyeaLaekgikavvtLeekkelrelgleyqagllvlhvpikDlsaPsekqveeivrlidall....dndkg.vvvHCraGvGRtGtvlAs 99 kd + e+g + ++tL+e el + + l+ ++pi++ aP ek + i+ ++++l d+d++ +v C+ G GRt t +A FUN_001140-T1 593 VYKDVNRSPEEQGFGSILTLRE---SAELCMAKNPQTLYFRLPISEDRAPEEKDFDRILSILNNLHeiyaDEDGPaIVFSCESGKGRTTTGMAI 683 446777777899*********5...56777777777999**************999999998875322225565548889*******9886663 PP >> PTP-SAK Swiss Army Knife protein, DSP-PTPase phosphatase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 9.2e-06 0.034 44 121 .. 236 322 .. 228 339 .. 0.77 2 ! 21.9 0.0 5.7e-08 0.00021 33 116 .. 607 692 .. 591 724 .. 0.77 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 9.2e-06 PTP-SAK 44 lpkgwfkldkavknlflpvenykapsdeqvdlllasllkr.....deektp...vlvHCgGGkGRa..GTvlacyLvafGfkppaaed 121 ++++ f ++ ++ +p+ +ap+++ d ++ ++++ +++++p ++ C G+GR+ G v+ c+++ + p++++ FUN_001140-T1 236 YSRQIFL-TPFLRYSRIPITATNAPEEQDFDQFISAIKDIlqlfdSNSSAPlpaMVFNCHVGQGRTttGMVIGCLIISHRTGFPSVAQ 322 5566665.78889999*****************999865466786666666887777899999996337799****999777777654 PP == domain 2 score: 21.9 bits; conditional E-value: 5.7e-08 PTP-SAK 33 ttvvtlteeeplpkgwfkldkavknlflpvenykapsdeqvdlllasllkr.....deektpvlvHCgGGkGRaGTvlacyLvafGfkp 116 ++tl+e+ +l + ++++ lp+++ +ap+++ d++l +l++ de+++ ++ C GkGR+ T +a+ +++ k+ FUN_001140-T1 607 GSILTLRESAELC---MAKNPQTLYFRLPISEDRAPEEKDFDRILSILNNLheiyaDEDGPAIVFSCESGKGRTTTGMAIAALIYCNKK 692 5677887666654...4448899999********************99876789977777667778********999998766555444 PP >> Y_phosphatase Protein-tyrosine phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.9 0.0 0.0034 13 156 196 .. 273 313 .. 255 324 .. 0.71 2 ! 12.7 0.0 2.8e-05 0.1 149 197 .. 642 691 .. 634 701 .. 0.79 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0034 Y_phosphatase 156 ellekvrkskeeeegpivvhCsaGvgRtgtfiaidillqql 196 ++l+ + +++++ +v C+ G gRt t ++i +l+ + FUN_001140-T1 273 DILQLFDSNSSAPLPAMVFNCHVGQGRTTTGMVIGCLIISH 313 4444444444555667899***************9998765 PP == domain 2 score: 12.7 bits; conditional E-value: 2.8e-05 Y_phosphatase 149 esaksllellekvrkskeeeegpivv.hCsaGvgRtgtfiaidillqqle 197 ++ + +l++l+++++ + +e+gp +v C++G gRt t +ai +l+ + + FUN_001140-T1 642 KDFDRILSILNNLHEIYADEDGPAIVfSCESGKGRTTTGMAIAALIYCNK 691 4578899999999999977777755538**************99987765 PP >> Baculo_PP31 Baculovirus 33KDa late protein (PP31) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.2 2e-05 0.072 44 88 .. 770 817 .. 753 836 .. 0.88 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2e-05 Baculo_PP31 44 lpvygddkktakrkKkiisnNkY...ILFNswytKirksewpnShtmW 88 ++++ ++k+ rkK +Y ILFN++ + +r+s+w S W FUN_001140-T1 770 NACTSHEKRLEHRKKSLFYLERYfylILFNTYLHMERRSKWKRSFCEW 817 678889**********99999998899***************998877 PP >> Y_phosphatase3 Tyrosine phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.017 64 116 143 .. 269 301 .. 252 312 .. 0.71 2 ? 7.7 0.0 0.0012 4.4 123 148 .. 655 685 .. 607 689 .. 0.78 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.017 Y_phosphatase3 116 aayravlealad.ee....pvlfHCtaGKDRTG 143 +a++++l+ + + + +++f+C++G RT FUN_001140-T1 269 SAIKDILQLFDSnSSaplpAMVFNCHVGQGRTT 301 456666666665322678889**********83 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0012 Y_phosphatase3 123 ealadee...pvlfHCtaGKDRT..Gvaaal 148 +++ ++e +++f C +GK RT G+a+a FUN_001140-T1 655 HEIYADEdgpAIVFSCESGKGRTttGMAIAA 685 334442247899**********733666554 PP >> PTP-NADK DSP-PTPase phosphatase fused to NAD+ Kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.006 22 80 122 .. 249 301 .. 233 324 .. 0.75 2 ? 3.2 0.0 0.021 76 80 123 .. 629 679 .. 602 695 .. 0.69 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.006 PTP-NADK 80 vkipvevgtaPtaeqVerfaelvsd.......sekrp...lyvhskeGvgRts 122 +ip+++++aP ++ ++f++ ++d +++ p + ++ G gRt+ FUN_001140-T1 249 SRIPITATNAPEEQDFDQFISAIKDilqlfdsNSSAPlpaMVFNCHVGQGRTT 301 59*******************99873333322333334445556666666664 PP == domain 2 score: 3.2 bits; conditional E-value: 0.021 PTP-NADK 80 vkipvevgtaPtaeqVerfaelvsd.......sekrplyvhskeGvgRtsa 123 ++p++ +aP ++ +r ++++++ ++ + +++ G gRt++ FUN_001140-T1 629 FRLPISEDRAPEEKDFDRILSILNNlheiyadEDGPAIVFSCESGKGRTTT 679 58999999999999998888887652222220444558899*******986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (863 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 573 (0.022431); expected 510.9 (0.02) Passed bias filter: 510 (0.0199648); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.38u 0.37s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 8442.11 // Query: FUN_001140-T2 [L=879] Description: FUN_001140 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-71 238.9 0.0 2.3e-40 138.8 0.0 3.0 3 PTPlike_phytase Inositol hexakisphosphate 5.5e-11 43.4 0.0 8.6e-05 23.5 0.0 2.7 2 Tc-R-P Polymorphic toxin system, DSP-PTPase phospha 1e-09 39.1 0.0 0.00021 21.8 0.0 2.4 2 PTP-SAK Swiss Army Knife protein, DSP-PTPase phospha 0.0003 21.0 0.0 0.1 12.7 0.0 2.3 2 Y_phosphatase Protein-tyrosine phosphatase ------ inclusion threshold ------ 0.035 14.1 0.2 0.073 13.0 0.2 1.4 1 Baculo_PP31 Baculovirus 33KDa late protein (PP31) 0.045 14.2 0.0 4.5 7.7 0.0 2.4 2 Y_phosphatase3 Tyrosine phosphatase family 0.26 11.2 0.0 22 4.9 0.0 2.6 2 PTP-NADK DSP-PTPase phosphatase fused to NAD+ Kinase Domain annotation for each model (and alignments): >> PTPlike_phytase Inositol hexakisphosphate # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.8 0.0 6.2e-44 2.3e-40 1 157 [. 158 326 .. 158 327 .. 0.95 2 ? -0.8 0.0 0.55 2e+03 117 141 .. 373 397 .. 367 398 .. 0.88 3 ! 96.4 0.0 6.7e-31 2.5e-27 1 157 [. 550 703 .. 550 704 .. 0.90 Alignments for each domain: == domain 1 score: 138.8 bits; conditional E-value: 6.2e-44 PTPlike_phytase 1 vnlReEpvv....yingrpyvlrekenllenlkeltgisaeeleklearlkkdvlaeakktggrvlvheetedgeevetvvevweevee..qtp 88 +nlReEpvv +++ py++r+++ l+ n+ +g+++eel++ e ++++++++ + ++gg++++++++e e+ + +v e e ++ FUN_001140-T2 158 FNLREEPVVfvglNHDYVPYSPRDPSSLKGNI-ANHGVKPEELADNELKIREEIIRLSIEEGGKFYFYNNVETLEDEPHPYKVVYE--EdlCVL 248 79*******999899****************9.99***************************************988887777554..356*** PP PTPlike_phytase 89 eevyeellaegpsvdYvRiPitdekapeeedfdalvsivketpe.........dtalvfnCqmGrgRTTtamviatLv 157 +e+y+++++ +p ++Y+RiPit+ +apee+dfd+++s++k+ + +a+vfnC++G+gRTTt+mvi++L+ FUN_001140-T2 249 DEIYSRQIFLTPFLRYSRIPITATNAPEEQDFDQFISAIKDILQlfdsnssapLPAMVFNCHVGQGRTTTGMVIGCLI 326 ******************************************777********************************9 PP == domain 2 score: -0.8 bits; conditional E-value: 0.55 PTPlike_phytase 117 eedfdalvsivketpedtalvfnCq 141 ++++d++++i++++++ ++++ C+ FUN_001140-T2 373 KQEVDSVIDICSDVMNLRSVIYVCK 397 689***********99999999996 PP == domain 3 score: 96.4 bits; conditional E-value: 6.7e-31 PTPlike_phytase 1 vnlReEpvvyingrpyvlrekenllenlkeltgisaeeleklearlkkdvlaeakktggrvlvheetedgeevetvvevweeveeqtpeevyee 94 +nlRe+ v ++g ++ re +n++e + g ++ e+ek e++lk+++l++ kk +v+ ++ +++ e + + t +e e FUN_001140-T2 550 FNLREDLAVDCDGSTFGSREISNVTEHM-PFRGLDTVEIEKKESDLKSELLRKGKKRPTKVY-KDVNRSPE-EQGFGSI------LTLRESAEL 634 79*************************9.9************************99999998.34444332.2222223......688999*** PP PTPlike_phytase 95 llaegpsvdYvRiPitdekapeeedfdalvsivketpe......dtalvfnCqmGrgRTTtamviatLv 157 +a++p+ Y+R+Pi++++apee+dfd ++si+ ++ e +a+vf+C+ G+gRTTt+m+ia L+ FUN_001140-T2 635 CMAKNPQTLYFRLPISEDRAPEEKDFDRILSILNNLHEiyadedGPAIVFSCESGKGRTTTGMAIAALI 703 ************************************888****************************98 PP >> Tc-R-P Polymorphic toxin system, DSP-PTPase phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 2.8e-06 0.01 47 104 .. 262 329 .. 244 331 .. 0.75 2 ! 23.5 0.0 2.4e-08 8.6e-05 11 99 .. 609 699 .. 601 706 .. 0.75 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 2.8e-06 Tc-R-P 47 llvlhvpikDlsaPsekqveeivrlidall...dndk..g...vvvHCraGvGRt..GtvlAsyLvrt 104 l + ++pi ++aP e+ ++++ i+++l d++ + +v C+ G GRt G v+ + ++ + FUN_001140-T2 262 LRYSRIPITATNAPEEQDFDQFISAIKDILqlfDSNSsaPlpaMVFNCHVGQGRTttGMVIGCLIISH 329 56789******************999987644444432233336889*******73366788877765 PP == domain 2 score: 23.5 bits; conditional E-value: 2.4e-08 Tc-R-P 11 aikddyeaLaekgikavvtLeekkelrelgleyqagllvlhvpikDlsaPsekqveeivrlidall....dndkg.vvvHCraGvGRtGtvlAs 99 kd + e+g + ++tL+e el + + l+ ++pi++ aP ek + i+ ++++l d+d++ +v C+ G GRt t +A FUN_001140-T2 609 VYKDVNRSPEEQGFGSILTLRE---SAELCMAKNPQTLYFRLPISEDRAPEEKDFDRILSILNNLHeiyaDEDGPaIVFSCESGKGRTTTGMAI 699 446777777899*********5...56777777777999**************999999998875322225565548889*******9886663 PP >> PTP-SAK Swiss Army Knife protein, DSP-PTPase phosphatase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 9.5e-06 0.035 44 121 .. 252 338 .. 244 355 .. 0.77 2 ! 21.8 0.0 5.9e-08 0.00021 33 116 .. 623 708 .. 607 740 .. 0.77 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 9.5e-06 PTP-SAK 44 lpkgwfkldkavknlflpvenykapsdeqvdlllasllkr.....deektp...vlvHCgGGkGRa..GTvlacyLvafGfkppaaed 121 ++++ f ++ ++ +p+ +ap+++ d ++ ++++ +++++p ++ C G+GR+ G v+ c+++ + p++++ FUN_001140-T2 252 YSRQIFL-TPFLRYSRIPITATNAPEEQDFDQFISAIKDIlqlfdSNSSAPlpaMVFNCHVGQGRTttGMVIGCLIISHRTGFPSVAQ 338 5566665.78889999*****************999865466786666666887777899999996337799****999777777654 PP == domain 2 score: 21.8 bits; conditional E-value: 5.9e-08 PTP-SAK 33 ttvvtlteeeplpkgwfkldkavknlflpvenykapsdeqvdlllasllkr.....deektpvlvHCgGGkGRaGTvlacyLvafGfkp 116 ++tl+e+ +l + ++++ lp+++ +ap+++ d++l +l++ de+++ ++ C GkGR+ T +a+ +++ k+ FUN_001140-T2 623 GSILTLRESAELC---MAKNPQTLYFRLPISEDRAPEEKDFDRILSILNNLheiyaDEDGPAIVFSCESGKGRTTTGMAIAALIYCNKK 708 5677887666654...4448899999********************99876789977777667778********999998766555444 PP >> Y_phosphatase Protein-tyrosine phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.8 0.0 0.0035 13 156 196 .. 289 329 .. 271 340 .. 0.71 2 ! 12.7 0.0 2.9e-05 0.1 149 197 .. 658 707 .. 650 717 .. 0.79 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0035 Y_phosphatase 156 ellekvrkskeeeegpivvhCsaGvgRtgtfiaidillqql 196 ++l+ + +++++ +v C+ G gRt t ++i +l+ + FUN_001140-T2 289 DILQLFDSNSSAPLPAMVFNCHVGQGRTTTGMVIGCLIISH 329 4444444444555667899***************9998765 PP == domain 2 score: 12.7 bits; conditional E-value: 2.9e-05 Y_phosphatase 149 esaksllellekvrkskeeeegpivv.hCsaGvgRtgtfiaidillqqle 197 ++ + +l++l+++++ + +e+gp +v C++G gRt t +ai +l+ + + FUN_001140-T2 658 KDFDRILSILNNLHEIYADEDGPAIVfSCESGKGRTTTGMAIAALIYCNK 707 4578899999999999977777755538**************99987765 PP >> Baculo_PP31 Baculovirus 33KDa late protein (PP31) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.2 2e-05 0.073 44 88 .. 786 833 .. 769 852 .. 0.88 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2e-05 Baculo_PP31 44 lpvygddkktakrkKkiisnNkY...ILFNswytKirksewpnShtmW 88 ++++ ++k+ rkK +Y ILFN++ + +r+s+w S W FUN_001140-T2 786 NACTSHEKRLEHRKKSLFYLERYfylILFNTYLHMERRSKWKRSFCEW 833 678889**********99999998899***************998877 PP >> Y_phosphatase3 Tyrosine phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.018 65 116 143 .. 285 317 .. 268 328 .. 0.71 2 ? 7.7 0.0 0.0012 4.5 123 148 .. 671 701 .. 623 705 .. 0.78 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.018 Y_phosphatase3 116 aayravlealad.ee....pvlfHCtaGKDRTG 143 +a++++l+ + + + +++f+C++G RT FUN_001140-T2 285 SAIKDILQLFDSnSSaplpAMVFNCHVGQGRTT 317 456666666665322678889**********83 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0012 Y_phosphatase3 123 ealadee...pvlfHCtaGKDRT..Gvaaal 148 +++ ++e +++f C +GK RT G+a+a FUN_001140-T2 671 HEIYADEdgpAIVFSCESGKGRTttGMAIAA 701 334442247899**********733666554 PP >> PTP-NADK DSP-PTPase phosphatase fused to NAD+ Kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.0062 22 80 122 .. 265 317 .. 249 339 .. 0.75 2 ? 3.1 0.0 0.021 78 80 123 .. 645 695 .. 618 711 .. 0.69 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0062 PTP-NADK 80 vkipvevgtaPtaeqVerfaelvsd.......sekrp...lyvhskeGvgRts 122 +ip+++++aP ++ ++f++ ++d +++ p + ++ G gRt+ FUN_001140-T2 265 SRIPITATNAPEEQDFDQFISAIKDilqlfdsNSSAPlpaMVFNCHVGQGRTT 317 59*******************99873333322333334445556666666664 PP == domain 2 score: 3.1 bits; conditional E-value: 0.021 PTP-NADK 80 vkipvevgtaPtaeqVerfaelvsd.......sekrplyvhskeGvgRtsa 123 ++p++ +aP ++ +r ++++++ ++ + +++ G gRt++ FUN_001140-T2 645 FRLPISEDRAPEEKDFDRILSILNNlheiyadEDGPAIVFSCESGKGRTTT 695 58999999999999998888887652222220444558899*******986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (879 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 594 (0.0232531); expected 510.9 (0.02) Passed bias filter: 529 (0.0207086); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.39u 0.41s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 8461.83 // Query: FUN_001141-T1 [L=1022] Description: FUN_001141 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-84 282.6 0.3 2.2e-84 282.1 0.3 1.2 1 MOZ_SAS MOZ/SAS family 6.3e-22 77.5 2.3 6.3e-22 77.5 2.3 2.7 3 zf-MYST MYST family zinc finger domain 5.4e-21 75.0 0.0 2.6e-20 72.8 0.1 2.2 2 SAMD1_WH SAM domain-containing protein 1, WH domai 5.8e-17 61.9 28.7 2e-11 44.2 6.3 3.5 3 PHD PHD-finger 2.1e-12 47.3 6.9 5.7e-12 46.0 6.9 1.8 1 zf-C2HC Zinc finger, C2HC type 2.2e-07 31.5 0.0 3.3e-06 27.7 0.0 2.4 2 Linker_histone linker histone H1 and H5 family 0.00019 22.0 8.3 0.00019 22.0 8.3 3.1 3 PHD-1st_NSD Histone-lysine N-methyltransferase NSD-li 0.00041 20.2 14.2 0.0012 18.7 0.4 3.2 2 PHD_2 PHD-finger 0.00045 20.7 14.6 0.091 13.3 3.6 3.3 3 PHDvar_NSD Histone-lysine N-methyltransferase NSD-li 0.0029 18.0 22.8 0.025 15.0 11.4 3.0 2 PHD_4 PHD-finger ------ inclusion threshold ------ 0.011 15.9 4.1 0.033 14.4 4.1 1.8 1 zf-C2H2_ZNF462_1st Zinc finger protein 462, first C2H2 zinc 0.015 16.0 0.0 0.046 14.4 0.0 1.9 1 Arteri_GP4 Arterivirus glycoprotein 0.031 15.1 0.0 0.07 14.0 0.0 1.5 1 Acetyltransf_7 Acetyltransferase (GNAT) domain 0.13 12.9 16.0 0.42 11.3 6.0 2.7 2 Prok-RING_1 Prokaryotic RING finger family 1 0.2 12.4 0.0 0.57 10.9 0.0 1.7 1 Acetyltransf_1 Acetyltransferase (GNAT) family 0.24 11.8 0.0 0.44 11.0 0.0 1.3 1 Cullin_AB Cullin alpha+beta domain 0.36 11.7 19.8 1.8 9.4 3.0 3.9 3 PHD_NSD Histone-lysine N-methyltransferase NSD-li 1.2 9.1 15.4 0.33 11.0 11.0 2.2 1 zf-PHD-like PHD/FYVE-zinc-finger like domain Domain annotation for each model (and alignments): >> MOZ_SAS MOZ/SAS family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 282.1 0.3 1.5e-87 2.2e-84 1 179 [. 500 677 .. 500 678 .. 0.98 Alignments for each domain: == domain 1 score: 282.1 bits; conditional E-value: 1.5e-87 MOZ_SAS 1 ppGkeiYrkeklsifevdGkkeklycqnLcllaklFLdhktlyydvepflfYvltevdeegahlvgyFskekesaeeynlaCiltlPpyqrkgyGk 96 pp++eiYrk+++s+fevdG+ +k+ycqnLcllaklFLdhktlyydvepflfY lt++d++g+hlvgyFskek+++++yn++Ci+t+P+yqr+gyG+ FUN_001141-T1 500 PPANEIYRKDDISVFEVDGAVNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYALTKNDKKGCHLVGYFSKEKSCQQKYNVSCIMTMPHYQRQGYGR 595 89********************************************************************************************** PP MOZ_SAS 97 llielsYeLskregkvgsPekplsdlgllsyrsywkeeilellkkkeekekisikeisketsikeeDvistlkelnllkkekg 179 lli++sY Ls++eg+ gsPekplsdlgl+syrsywk+++le+l+++ ++++++i+ isk+t+++ +D+ +tl+ ln+++k++g FUN_001141-T1 596 LLIDFSYLLSRIEGQPGSPEKPLSDLGLISYRSYWKSVLLEYLHDH-KEKHVTIRGISKSTGMDPHDIAATLQILNMVQKRDG 677 ********************************************98.779****************************99876 PP >> zf-MYST MYST family zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 2.7 3.8e+03 26 38 .. 253 265 .. 251 267 .. 0.85 2 ! 77.5 2.3 4.4e-25 6.3e-22 4 55 .] 444 495 .. 441 495 .. 0.96 3 ? -2.1 0.1 3.2 4.5e+03 21 41 .. 523 543 .. 513 545 .. 0.77 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 2.7 zf-MYST 26 ytnvkkLyvCefC 38 n+++L +C+ C FUN_001141-T1 253 AGNADNLLFCDAC 265 57899******99 PP == domain 2 score: 77.5 bits; conditional E-value: 4.4e-25 zf-MYST 4 iekielGeyeietWYfSpYPeeytnvkkLyvCefClkYmksrkelkrHlkkC 55 i++G+yei tWY+SpYP+ey++ kLy+CefClkYmks + l rH++kC FUN_001141-T1 444 PPLIQFGRYEIVTWYSSPYPQEYARLPKLYLCEFCLKYMKSTSILMRHMTKC 495 5679************************************************ PP == domain 3 score: -2.1 bits; conditional E-value: 3.2 zf-MYST 21 pYPeeytnvkkLyvCefClkY 41 +Y ++++ kL++ +l+Y FUN_001141-T1 523 IYCQNLCLLAKLFLDHKTLYY 543 677888888899998888888 PP >> SAMD1_WH SAM domain-containing protein 1, WH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.8 0.1 1.8e-23 2.6e-20 2 63 .] 28 89 .. 27 89 .. 0.99 2 ? -1.8 0.0 3.6 5.1e+03 22 49 .. 129 159 .. 126 172 .. 0.74 Alignments for each domain: == domain 1 score: 72.8 bits; conditional E-value: 1.8e-23 SAMD1_WH 2 wiLeaIdklrkrKaRPdleRIcnavrrkhgiskedieeeLeklveegivlkVeyKGsiSYrn 63 wi++aI k++ +K+RP+ +RI+++++ +g++ + e+Le +v++g+vlkV +K++ SY++ FUN_001141-T1 28 WIIQAIGKVKGQKQRPSEDRISHILETVYGLDPQVALEQLELCVKTGKVLKVVFKDKASYKD 89 9************************************************************8 PP == domain 2 score: -1.8 bits; conditional E-value: 3.6 SAMD1_WH 22 Icnavrrkhgi...skedieeeLeklveegi 49 I n+v ++h s +d++++L+++ ++g FUN_001141-T1 129 IGNYVTQHHAAvldSPSDTQTRLKESLKRGL 159 8899999997656677888888888888775 PP >> PHD PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 9.7 6.3e-09 8.9e-06 1 47 [] 191 244 .. 191 244 .. 0.77 2 ! 44.2 6.3 1.4e-14 2e-11 1 47 [] 247 291 .. 247 291 .. 0.97 3 ? -1.6 0.1 2.8 4e+03 42 47 .] 473 478 .. 462 500 .. 0.68 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 6.3e-09 PHD 1 CkvCkk......sdedeelvlCdgCkkwfHlkClkpplekeelpeg.ewlCpeC 47 C +C++ + e+eel++C +C+++ H++Clk++ + + + ++ w+C eC FUN_001141-T1 191 CGFCQGtaqcnkDGEEEELISCADCGNSGHPSCLKYSPQLTARIKQePWQCIEC 244 555555555544999*******************9877755554444******* PP == domain 2 score: 44.2 bits; conditional E-value: 1.4e-14 PHD 1 CkvCkksdedeelvlCdgCkkwfHlkClkpplekeelpegewlCpeC 47 C+vC++ + ++l++Cd C+k fH++Cl+pp++ e p+g+w+C+ C FUN_001141-T1 247 CSVCQDAGNADNLLFCDACDKGFHMECLSPPMT--ETPTGSWVCSGC 291 *********************************..888899****99 PP == domain 3 score: -1.6 bits; conditional E-value: 2.8 PHD 42 wlCpeC 47 +lC+ C FUN_001141-T1 473 YLCEFC 478 566555 PP >> zf-C2HC Zinc finger, C2HC type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.0 6.9 4e-15 5.7e-12 2 29 .] 332 359 .. 331 359 .. 0.97 Alignments for each domain: == domain 1 score: 46.0 bits; conditional E-value: 4e-15 zf-C2HC 2 CPtpGCdGsGHisGkyatHrslsgCPya 29 CPtpGCdG+GH++G+ ++Hrs+ +CP+a FUN_001141-T1 332 CPTPGCDGTGHVNGRSTSHRSATACPVA 359 **************************97 PP >> Linker_histone linker histone H1 and H5 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.5 7.1e+02 2 53 .. 23 74 .. 22 101 .. 0.85 2 ! 27.7 0.0 2.4e-09 3.3e-06 5 61 .. 108 166 .. 104 169 .. 0.93 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.5 Linker_histone 2 psysemIkeAIkalke.rkGsSrqaIkkyikanykvgdvkkfksllkkaLkkg 53 p+y+ I++AI + k ++ S I +++ y + d++ + +l +k+g FUN_001141-T1 23 PKYAMWIIQAIGKVKGqKQRPSEDRISHILETVYGL-DPQVALEQLELCVKTG 74 899999******999978999999999999999998.8877766665555554 PP == domain 2 score: 27.7 bits; conditional E-value: 2.4e-09 Linker_histone 5 semIkeAIkalkerkGsSrqaIkkyikanykvg..dvkkfksllkkaLkkgvekgtlvq 61 e IkeA+++ + +G+++++I +y+++++ + +++ +++lk +Lk+g++++++++ FUN_001141-T1 108 TEFIKEALENIGDENGCTLPQIGNYVTQHHAAVldSPSDTQTRLKESLKRGLASEAFIK 166 688****************************999888888***************9976 PP >> PHD-1st_NSD Histone-lysine N-methyltransferase NSD-like, PHD zinc finger 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 4.9 3.3 4.7e+03 10 36 .. 199 227 .. 192 245 .. 0.64 2 ! 22.0 8.3 1.3e-07 0.00019 6 49 .] 245 292 .. 240 292 .. 0.83 3 ? -2.1 0.1 4.6 6.5e+03 6 29 .. 473 499 .. 471 500 .. 0.67 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 3.3 PHD-1st_NSD 10 lCEklGd..lLlCEgeCCgaFHleCLGLs 36 C+k G+ L+ ++C + H CL s FUN_001141-T1 199 QCNKDGEeeELISCADCGNSGHPSCLKYS 227 699999633699779**********9754 PP == domain 2 score: 22.0 bits; conditional E-value: 1.3e-07 PHD-1st_NSD 6 tvCqlCEklG..dlLl.CEgeCCgaFHleCLG..LselPegkFiCeECk 49 +vC +C +G d Ll C++ C + FH+eCL ++e P g ++C+ Ck FUN_001141-T1 245 KVCSVCQDAGnaDNLLfCDA-CDKGFHMECLSppMTETPTGSWVCSGCK 292 58999999884434554987.**********76699************7 PP == domain 3 score: -2.1 bits; conditional E-value: 4.6 PHD-1st_NSD 6 tvCqlC...EklGdlLlCEgeCCgaFH 29 + C C k+ ++L+ C+ FH FUN_001141-T1 473 YLCEFClkyMKSTSILMRHMTKCKWFH 499 567777222356777888888899998 PP >> PHD_2 PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 3.0 0.0012 1.7 2 35 .. 207 244 .. 206 245 .. 0.81 2 ! 18.7 0.4 8.5e-07 0.0012 2 36 .] 257 292 .. 256 292 .. 0.85 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0012 PHD_2 2 splivCskCsisVHasCYGveeesd....eeewlCsrC 35 ++li+C++C s H sC + +++ + +e+w C C FUN_001141-T1 207 EELISCADCGNSGHPSCLKYSPQLTarikQEPWQCIEC 244 579**************999998763332567999999 PP == domain 2 score: 18.7 bits; conditional E-value: 8.5e-07 PHD_2 2 splivCskCsisVHasCYGveeesdeee.wlCsrCa 36 + l++C+ C +H++C + +++++ w+Cs C+ FUN_001141-T1 257 DNLLFCDACDKGFHMECLSPPMTETPTGsWVCSGCK 292 679**************977777777666******5 PP >> PHDvar_NSD Histone-lysine N-methyltransferase NSD-like, variant PHD zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 1.7 9.6e-05 0.14 2 30 .. 198 226 .. 197 241 .. 0.89 2 ? -2.5 0.1 5.5 7.9e+03 10 19 .. 235 244 .. 231 246 .. 0.81 3 ! 13.3 3.6 6.4e-05 0.091 1 35 [. 247 281 .. 247 291 .. 0.85 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 9.6e-05 PHDvar_NSD 2 akCeqSgdskeivrClrCPkAYHlkClpk 30 a+C++ g+++e++ C C ++ H +Cl+ FUN_001141-T1 198 AQCNKDGEEEELISCADCGNSGHPSCLKY 226 79************************964 PP == domain 2 score: -2.5 bits; conditional E-value: 5.5 PHDvar_NSD 10 skeivrClrC 19 ++e +C+ C FUN_001141-T1 235 KQEPWQCIEC 244 577899**99 PP == domain 3 score: 13.3 bits; conditional E-value: 6.4e-05 PHDvar_NSD 1 CakCeqSgdskeivrClrCPkAYHlkClpkkvkrl 35 C+ C+ g+ +++ C C k +H+ Cl + + FUN_001141-T1 247 CSVCQDAGNADNLLFCDACDKGFHMECLSPPMTET 281 ****************************7766655 PP >> PHD_4 PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 11.4 1.8e-05 0.025 6 62 .. 190 245 .. 186 248 .. 0.77 2 ? 6.1 5.9 0.011 15 6 64 .. 246 291 .. 245 292 .. 0.87 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1.8e-05 PHD_4 6 vCivCgedekedeveseteeelleCsiCyeivHpeClkekngeg.vvnddlpnsWeCp 62 C +C+ + + + ++ +eeel+ C+ C ++ Hp+Clk + + + ++++ ++ eC FUN_001141-T1 190 FCGFCQGTAQCN--KDGEEEELISCADCGNSGHPSCLKYSPQLTaRIKQEPWQCIECK 245 699999999998..79999********************6544435555555555555 PP == domain 2 score: 6.1 bits; conditional E-value: 0.011 PHD_4 6 vCivCgedekedeveseteeelleCsiCyeivHpeClkekngegvvnddlpnsWeCpkC 64 vC+vC+++++ d +ll C C H eCl+ + + sW C+ C FUN_001141-T1 246 VCSVCQDAGNAD--------NLLFCDACDKGFHMECLSP-P----MTETPTGSWVCSGC 291 7999*9999999........7****************99.4....66677789999998 PP >> zf-C2H2_ZNF462_1st Zinc finger protein 462, first C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 4.1 2.3e-05 0.033 2 24 .. 472 494 .. 471 498 .. 0.92 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.3e-05 zf-C2H2_ZNF462_1st 2 fFQCkfCVrYFRSKsLLleHtkK 24 ++ C fC +Y +S s+L+ H+ K FUN_001141-T1 472 LYLCEFCLKYMKSTSILMRHMTK 494 688******************98 PP >> Arteri_GP4 Arterivirus glycoprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 3.2e-05 0.046 122 170 .. 672 720 .. 663 722 .. 0.90 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 3.2e-05 Arteri_GP4 122 fanssgtlvlCvnatetvahlenktfeppvflsPgalrWAtvitlilai 170 +++ +g vlCvn +h+++ + l P alrW + + la+ FUN_001141-T1 672 VQKRDGKFVLCVNQRLISSHMDKLRKSNRTSLDPDALRWTPLVHTNLAL 720 5678999******************99************9999988886 PP >> Acetyltransf_7 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 4.9e-05 0.07 15 53 .. 564 601 .. 547 618 .. 0.70 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 4.9e-05 Acetyltransf_7 15 vGfaallpeddeaalae.erlaVdpeyrgkGiGraLleaa 53 vG+ + ++ +++ ++ +++ p y+++G+Gr L+++ FUN_001141-T1 564 VGYFSKEKSCQQK--YNvSCIMTMPHYQRQGYGRLLIDFS 601 4444433333333..56677*****************964 PP >> Prok-RING_1 Prokaryotic RING finger family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 3.6 0.021 30 7 40 .. 191 229 .. 186 243 .. 0.68 2 ? 11.3 6.0 0.00029 0.42 5 36 .. 245 275 .. 241 276 .. 0.87 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.021 Prok-RING_1 7 CtvCseel...kdg..dDiVvCdeCgtsyHreCykkaGk 40 C C+++ kdg ++++ C Cg s H C k+ + FUN_001141-T1 191 CGFCQGTAqcnKDGeeEELISCADCGNSGHPSCLKYSPQ 229 5566665522234422369***************99755 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00029 Prok-RING_1 5 kkCtvCseelkdgdDiVvCdeCgtsyHreCyk 36 k C vC++ ++d++ Cd+C +H eC + FUN_001141-T1 245 KVCSVCQDA-GNADNLLFCDACDKGFHMECLS 275 569999987.6789****************75 PP >> Acetyltransf_1 Acetyltransferase (GNAT) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00041 0.57 43 82 .. 559 599 .. 529 602 .. 0.70 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00041 Acetyltransf_1 43 e...lvGfaglsildeaekvaeieglaVdpeyrgkGiGtaLle 82 + lvG+ + + ++++ + +++ p y+++G+G+ L++ FUN_001141-T1 559 KgchLVGYFSKEKS--CQQKYNVSCIMTMPHYQRQGYGRLLID 599 24556666633333..558889999****************97 PP >> Cullin_AB Cullin alpha+beta domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00031 0.44 73 116 .. 629 674 .. 619 699 .. 0.78 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00031 Cullin_AB 73 yqmviLllFnd..eeeslsyeeiqeatglpeeelkrtLqsLavakk 116 y ++Ll + + +e++++++ i+++tg++ +++ +tLq+L + +k FUN_001141-T1 629 YWKSVLLEYLHdhKEKHVTIRGISKSTGMDPHDIAATLQILNMVQK 674 5567888554334889*************************65553 PP >> PHD_NSD Histone-lysine N-methyltransferase NSD-like, PHD zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 3.0 0.0013 1.8 7 54 .. 199 241 .. 189 243 .. 0.79 2 ? 7.9 3.5 0.0036 5.2 4 39 .. 246 276 .. 242 290 .. 0.77 3 ? 2.3 0.2 0.2 2.9e+02 25 45 .. 570 590 .. 568 596 .. 0.86 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.0013 PHD_NSD 7 aCgklgssdskaevfkCsvasCgkfYHpkCvaklpltkveaagesftC 54 C+k g+ ++e++ C a+Cg+ Hp+C++ p+ +++ ++e ++C FUN_001141-T1 199 QCNKDGE---EEELISC--ADCGNSGHPSCLKYSPQLTARIKQEPWQC 241 3555555...799**99..68***********9998888778888888 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0036 PHD_NSD 4 qCfaCgklgssdskaevfkCsvasCgkfYHpkCvak 39 C +C++ g+ ++++ C+ C k +H +C++ FUN_001141-T1 246 VCSVCQDAGN---ADNLLFCD--ACDKGFHMECLSP 276 6999999999...689999*6..7*********986 PP == domain 3 score: 2.3 bits; conditional E-value: 0.2 PHD_NSD 25 vasCgkfYHpkCvaklpltkv 45 +sC++ Y +C+ ++p+ + FUN_001141-T1 570 EKSCQQKYNVSCIMTMPHYQR 590 689***********9998765 PP >> zf-PHD-like PHD/FYVE-zinc-finger like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 11.0 0.00023 0.33 50 143 .. 189 280 .. 178 286 .. 0.80 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00023 zf-PHD-like 50 lqCrrCigvak.kkdktaPkldaCqeCkeeg.asckpfrekktakqeeklreendGedPitevdeelinnaenvlfrCakCkrafhfehlpskskk 143 + C +C g+a+ +kd + +l C++C ++g +sc +++++ ta+ ++ + + + + +v ++ na+n+lf C C ++fh+e+l + ++ FUN_001141-T1 189 IFCGFCQGTAQcNKDGEEEELISCADCGNSGhPSCLKYSPQLTARIKQEPWQCIECK--VCSVCQD-AGNADNLLF-CDACDKGFHMECLSPPMTE 280 45999999875389999**********9998459**********9998866655544..5555554.6899***99.*************887665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1022 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1600 (0.0626346); expected 510.9 (0.02) Passed bias filter: 835 (0.0326874); expected 510.9 (0.02) Passed Vit filter: 126 (0.00493247); expected 25.5 (0.001) Passed Fwd filter: 31 (0.00121354); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.49u 0.44s 00:00:00.93 Elapsed: 00:00:00.44 # Mc/sec: 9420.49 // Query: FUN_001142-T1 [L=190] Description: FUN_001142 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-29 103.1 0.4 2.4e-29 102.3 0.4 1.4 1 Bcl-2 Apoptosis regulator proteins, Bcl-2 family 0.0021 18.2 0.3 0.0035 17.5 0.3 1.3 1 BH4 Bcl-2 homology region 4 ------ inclusion threshold ------ 0.018 15.7 0.3 0.086 13.5 0.1 2.2 2 DUF2200 Uncharacterized protein conserved in bacteria (DUF2 0.058 14.1 0.0 0.13 12.9 0.0 1.5 2 WHD_CYT4 Mitochondrial protein cyt-4, winged helix Domain annotation for each model (and alignments): >> Bcl-2 Apoptosis regulator proteins, Bcl-2 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.3 0.4 3.8e-33 2.4e-29 1 100 [] 50 149 .. 50 149 .. 0.98 Alignments for each domain: == domain 1 score: 102.3 bits; conditional E-value: 3.8e-33 Bcl-2 1 LrrlgdeleekheeelesmleqlelteetarelfrevaeelfsdgeinWgrvvalfafagalavklvrq.gqeelveklaewlaeyleeeladWir 95 Lrr++del e+++++++sm++ql+lt ++++ +f +a+e+f++g nWgr+va++af+++lav +v++ + el+++++ewl+ y+e++l++Wi+ FUN_001142-T1 50 LRRVADELIEENRQLFDSMCDQLHLTHASTYATFVGIADEIFQTG-KNWGRIVAFLAFGATLAVYCVQKeDLAELLDNIIEWLSLYMEQNLGQWIN 144 89************************9*****************9.*********************99668999********************* PP Bcl-2 96 eqgGW 100 e+gGW FUN_001142-T1 145 ENGGW 149 ***** PP >> BH4 Bcl-2 homology region 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.3 5.5e-07 0.0035 8 21 .. 18 31 .. 17 32 .. 0.91 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 5.5e-07 BH4 8 LVvDyvsYKLsQrG 21 +V Dyv+YKL+Q++ FUN_001142-T1 18 IVKDYVGYKLRQKN 31 588**********8 PP >> DUF2200 Uncharacterized protein conserved in bacteria (DUF2200) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.44 2.8e+03 78 100 .. 49 72 .. 40 80 .. 0.77 2 ? 13.5 0.1 1.3e-05 0.086 20 58 .. 116 154 .. 100 175 .. 0.85 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.44 DUF2200 78 rveeiedplmkkiryl.dklvDel 100 ++ + d+l+++ r+l d + D+l FUN_001142-T1 49 HLRRVADELIEENRQLfDSMCDQL 72 456788999999887658888877 PP == domain 2 score: 13.5 bits; conditional E-value: 1.3e-05 DUF2200 20 kkgrtkeevdevieWltgydeeelqelieekvtfetffe 58 +k+ +e +d++ieWl y e++l + i+e+ +e f++ FUN_001142-T1 116 QKEDLAELLDNIIEWLSLYMEQNLGQWINENGGWEGFIQ 154 566778889*********************998887765 PP >> WHD_CYT4 Mitochondrial protein cyt-4, winged helix # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 2e-05 0.13 13 55 .. 52 95 .. 49 107 .. 0.89 2 ? -3.5 0.0 2.7 1.7e+04 23 33 .. 121 131 .. 118 133 .. 0.76 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 2e-05 WHD_CYT4 13 eeaeefyrenasrLDnayelladetelryltleeiaeklLgi.e 55 + a+e+ +en + +D++ ++l+ + +y t+ ia++++++ + FUN_001142-T1 52 RVADELIEENRQLFDSMCDQLHLTHASTYATFVGIADEIFQTgK 95 6689999*********************************9843 PP == domain 2 score: -3.5 bits; conditional E-value: 2.7 WHD_CYT4 23 asrLDnayell 33 a+ LDn+ e l FUN_001142-T1 121 AELLDNIIEWL 131 67899998866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (190 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 995 (0.0389509); expected 510.9 (0.02) Passed bias filter: 866 (0.033901); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1883.55 // Query: FUN_001143-T1 [L=86] Description: FUN_001143 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (86 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 488 (0.0191035); expected 510.9 (0.02) Passed bias filter: 389 (0.015228); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.43s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 886.73 // Query: FUN_001144-T1 [L=200] Description: FUN_001144 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-07 31.0 5.3 4.9e-07 30.4 5.3 1.4 1 MANEC MANEC domain ------ inclusion threshold ------ 0.018 15.6 0.8 0.039 14.5 0.8 1.6 1 PAN_4 PAN domain Domain annotation for each model (and alignments): >> MANEC MANEC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 5.3 3.9e-11 4.9e-07 22 84 .. 50 115 .. 25 119 .. 0.82 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 3.9e-11 MANEC 22 keGakfle.saevsseedCvraCCkekkCnlalleekke....eekkksCyLfnClyeskfvCkfakk 84 ++G + v+s+ dC + CC + +C+++l+ ++ +++k +C+ +nC + ++ C++++ FUN_001144-T1 50 NNGTVSVPkALIVNSSMDCEQGCCGNINCTVYLFYPRQPsiedQQRKFNCFFLNC--RPQNLCSLVNV 115 566555543667899*******************99988898889999*******..88899999875 PP >> PAN_4 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.8 3.1e-06 0.039 13 38 .. 60 85 .. 47 100 .. 0.79 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.1e-06 PAN_4 13 llvdspeaCcaaCdedprCnawvfvk 38 l v+s +C + C+ + +C+++ f + FUN_001144-T1 60 LIVNSSMDCEQGCCGNINCTVYLFYP 85 5899******************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (200 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 932 (0.0364846); expected 510.9 (0.02) Passed bias filter: 541 (0.0211783); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2020.46 // Query: FUN_001145-T1 [L=211] Description: FUN_001145 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-50 169.4 0.0 1.2e-49 169.0 0.0 1.1 1 CCDC53 Subunit CCDC53 of WASH complex Domain annotation for each model (and alignments): >> CCDC53 Subunit CCDC53 of WASH complex # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 169.0 0.0 4.6e-54 1.2e-49 1 146 [] 30 178 .. 30 178 .. 0.78 Alignments for each domain: == domain 1 score: 169.0 bits; conditional E-value: 4.6e-54 CCDC53 1 lNqfvvstvqfLNrFsavcEekLveverrlqkleatlaiLeakLsSipgleevtaeaae.taaasnaepseessaeeaeaaaqaeepseae.eeae 94 lN+f+++ v+fLNrFs+vcEekL+++++++q++e+ ++iLeakL+Sipgle+vt+++ + a+++n++ s +s + +a a ++++s+a+ + a+ FUN_001145-T1 30 LNHFITHSVRFLNRFSCVCEEKLADLSSKIQRIEIMMSILEAKLASIPGLEDVTVSTPPpPASQTNGPISGASMSGPAPPPAIDAPQSAADgPPAP 125 7*******************************************************8776555555555555555444444433333333212222 PP CCDC53 95 eeeeeeeese...nvltvkkDpryakYfkmlkvGVPeqavknKmeseGldpslLd 146 + ee e+ e +++tv+kDpryakYf+m+kvGVP qa+ Km++eGldpslLd FUN_001145-T1 126 PIEEPEP--EperPTMTVSKDPRYAKYFQMVKVGVPPQAIAPKMIAEGLDPSLLD 178 2222222..13469****************************************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 728 (0.0284987); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2106.03 // Query: FUN_001146-T1 [L=553] Description: FUN_001146 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.1 9.3 4.0 0.92 9.5 2.1 1.8 1 Allexi_40kDa Allexivirus 40kDa protein 3.2 8.6 8.5 0.46 11.3 2.7 2.3 2 HH_EMRA EMRA, alpha-helical hairpin domain Domain annotation for each model (and alignments): >> Allexi_40kDa Allexivirus 40kDa protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 2.1 7.2e-05 0.92 78 137 .. 131 188 .. 114 226 .. 0.82 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 7.2e-05 Allexi_40kDa 78 tlLselrdalrtltktldklksvekklelsaetasdskllkklesietsleelhakldel 137 t++++l +a ++l++ + ++++ +k s+++ ++ + k+le +et+le l ++l+ FUN_001146-T1 131 TEIERLEEAQTALEDRVRHVRELINKRDRSKNQRKQGQ--KTLERLETKLEMLDQRLEYE 188 6788999999*************999999988887766..99**************9644 PP >> HH_EMRA EMRA, alpha-helical hairpin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 2.7 3.6e-05 0.46 7 50 .. 136 179 .. 133 194 .. 0.91 2 ? -0.3 0.5 0.14 1.8e+03 38 75 .. 219 258 .. 182 277 .. 0.64 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 3.6e-05 HH_EMRA 7 lekAkaaLAqaVRqvrqliinskqlqanvalreiaLaraqaDla 50 le+A++aL + VR+vr+li + ++++++ ++ + +L+r ++ l+ FUN_001146-T1 136 LEEAQTALEDRVRHVRELINKRDRSKNQRKQGQKTLERLETKLE 179 89************************************999886 PP == domain 2 score: -0.3 bits; conditional E-value: 0.14 HH_EMRA 38 reiaLaraqaDl..arreaLaksgavskEelqhArdavas 75 r+ ++a+a + +r + + ++ v++Ee +++++a+ + FUN_001146-T1 219 RKLGAEQANASFseQRDNVIEEELEVDEEEREKSEEALFK 258 4445556666553246666677777888888888887533 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (553 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1737 (0.0679977); expected 510.9 (0.02) Passed bias filter: 590 (0.0230965); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5274.39 // Query: FUN_001147-T1 [L=477] Description: FUN_001147 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-31 109.9 0.0 2.5e-31 109.4 0.0 1.2 1 Peptidase_M28 Peptidase family M28 3.5e-05 24.3 0.0 9.5e-05 22.9 0.0 1.8 1 Peptidase_M20 Peptidase family M20/M25/M40 0.0097 16.5 0.0 0.04 14.5 0.0 2.0 2 PA PA domain ------ inclusion threshold ------ 0.19 12.2 0.0 2.1 8.8 0.0 2.1 2 Lit Lipoprotein intramolecular transacylase Lit Domain annotation for each model (and alignments): >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.4 0.0 3.9e-35 2.5e-31 1 191 [. 275 462 .. 275 464 .. 0.89 Alignments for each domain: == domain 1 score: 109.4 bits; conditional E-value: 3.9e-35 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaaskqqpkrsvrflffdaEEagllGSkafakskp.elkkiravlnlDm 94 N +a+++g+++ ++v+l+s+HlDs++vg+GA+D+++g+ + ++++ v+++ + +pkr++r+++++aEE+g+lG++ + ++++ ++ ++ +v++ D FUN_001147-T1 275 NTVAEIRGSKYpEQVVLVSGHLDSWDVGQGAMDDGAGAFISWKALSVIRQLGLKPKRTMRMVMWTAEEEGVLGAQEYYHRHKaSNGNFSLVMESDY 370 89*********888****************************************************************95555999********** PP Peptidase_M28 95 igsggkallfqsgpktsselekylkaaakpvgktlaedpfqergipgrsDhapfakagipaldlaetkfkery..HtpkDtldnidkdalqrvael 188 + +llf g+++++++ +++ ++ +p++ + ++ +p++ D + ++++g+pa +l++++ k+++ Ht+ Dt++ d+d+l+ +++l FUN_001147-T1 371 GTFTPLGLLF-KGSEKAAAIMREVMKLLQPINAS---EL---MLGPVSGDIVFWVNEGVPAGSLKTANSKYYFfhHTSGDTMAVEDPDSLDLCTAL 459 ********99.77777777777777788887653...44...45899*****************55555554467*****************9998 PP Peptidase_M28 189 vla 191 ++ FUN_001147-T1 460 WAV 462 876 PP >> Peptidase_M20 Peptidase family M20/M25/M40 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.0 1.5e-08 9.5e-05 30 81 .. 302 353 .. 298 456 .. 0.89 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.5e-08 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M20 30 GrGhddhkggllaalealralkeeglkpkgtvkllfqpdEEggsgGakalie 81 G G+ d+ +g ++ +al+ +++ glkpk+t +++++++EE g Ga+++ + FUN_001147-T1 302 GQGAMDDGAGAFISWKALSVIRQLGLKPKRTMRMVMWTAEEEGVLGAQEYYH 353 88***************************************7669*999888 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 6.2e-06 0.04 23 93 .. 164 245 .. 138 247 .. 0.72 2 ? -2.3 0.0 1.1 6.9e+03 27 55 .. 287 314 .. 268 319 .. 0.77 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 6.2e-06 PA 23 f.....dvkGkivLvqrGectf.......aeKvrnAqaaGAagviiynnvegglgapteaggeeleadpitiPavgiskadge 93 +vkGkiv+ ++ + + +++ G+ + +i + ++ + +++ag+++ e+ +iP++ i+ +d+e FUN_001147-T1 164 LrakapEVKGKIVVFNEKWVNYqvtvayrSKGASEVAKLGGLASLIRSVTPF-SIYSPHAGQQSYEKGVRKIPTACITIEDAE 245 1334449********654222245667767778899***********99965.4455666667777889*********99987 PP == domain 2 score: -2.3 bits; conditional E-value: 1.1 PA 27 GkivLvqrGectfaeKvrnAqaaGAagvi 55 ++vLv G + + ++ A + GA ++i FUN_001147-T1 287 EQVVLV-SGHLDSWDVGQGAMDDGAGAFI 314 468888.8888888888888888888888 PP >> Lit Lipoprotein intramolecular transacylase Lit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.00033 2.1 3 59 .. 7 61 .. 5 68 .. 0.86 2 ? 0.9 0.0 0.091 5.8e+02 69 107 .. 368 419 .. 349 438 .. 0.80 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00033 Lit 3 llillllvilllsieltinfkplyeleikklkleeavglskeellknykeliaYlnd 59 ++ + +l++l+ls ++tin+ ++ ++ k++++v+ + + +++++++i++l++ FUN_001147-T1 7 TSCCPFLFVLSLSFAITINA--ASYKAVNAVKVSSKVKSEVASHQEDAQKIIDFLTK 61 56778999999999999999..455789999***********************985 PP == domain 2 score: 0.9 bits; conditional E-value: 0.091 Lit 69 s...........fpssesglaHfedVkkLfllaylvllislill..ilflik 107 s f+ se+++a +++V kL++ +++ l++ +++ i+f+++ FUN_001147-T1 368 SdygtftplgllFKGSEKAAAIMREVMKLLQPINASELMLGPVSgdIVFWVN 419 34455555556689999*****************999999999977777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (477 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 735 (0.0287728); expected 510.9 (0.02) Passed bias filter: 663 (0.0259542); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4648.75 // Query: FUN_001148-T1 [L=724] Description: FUN_001148 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-191 638.2 17.5 1.8e-191 637.8 17.5 1.1 1 Suf Suppressor of forked protein (Suf) 3.8e-37 128.4 17.9 2.3e-26 93.4 2.7 4.6 5 HAT_PRP39_N PRP39 N-terminal HAT repeat 7.5e-22 78.4 25.7 5.2e-12 46.5 5.4 5.7 5 HAT_PRP39_C PRP39 C-terminal HAT repeat 1.3e-19 71.1 14.8 3.6e-05 24.1 3.4 5.1 5 HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-ter 5.1e-06 27.1 0.9 3.7 9.0 0.1 6.1 7 TPR_14 Tetratricopeptide repeat 2e-05 24.0 18.0 0.012 14.9 2.7 4.1 4 HAT_Syf1_CNRKL1_C Pre-mRNA-splicing factor Syf1/CRNKL1 C-ter 0.0046 16.6 12.0 1.7 8.1 0.4 5.4 4 NRDE-2 NRDE-2, necessary for RNA interference ------ inclusion threshold ------ 0.013 15.8 0.3 2.7 8.3 0.0 3.6 4 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR 0.73 10.3 13.8 0.94 9.9 4.7 4.7 4 Mad3_BUB1_I Mad3/BUB1 homology region 1 Domain annotation for each model (and alignments): >> Suf Suppressor of forked protein (Suf) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 637.8 17.5 6.3e-195 1.8e-191 5 532 .] 37 556 .. 33 556 .. 0.98 Alignments for each domain: == domain 1 score: 637.8 bits; conditional E-value: 6.3e-195 Suf 5 kledrieenpldieawleLikeaqskdkieevrevyekllkqFplaarlWkayieaelkrkefeeveklfsrcLlkvldveLWklYldYvrrkndl 100 k+e r++++p+d+e+w Li+eaqs ++e +r + ekl+++Fp+a+r+W+ yie+e+k++++e+veklf++cL+kvl+++LWk+Yl+Yvr+++ FUN_001148-T1 37 KAETRLQNHPYDTESWGVLIREAQST-PLETSRVLCEKLVRRFPNAGRYWRLYIEQEIKNNNYEQVEKLFQKCLIKVLNIDLWKCYLSYVRDTK-- 129 7899**********************.9******************************************************************.. PP Suf 101 itggeearetvikAyefalekigldieSgsiwadYiqflksvkavskweeqqkidaiRkvYkralvvPlenieklwkeYtqfEqevnkltarkfia 196 + ++r ++++Ayefalek+g+d +S++iw d+++flk+++av++++e+ ki +iRkvY+ra+v+P+ n+e+lw+eY++fEq+vnk++a+k+i+ FUN_001148-T1 130 -CSLPNFRDKMLQAYEFALEKVGVDFNSYQIWIDFVNFLKTGEAVGSYAENRKIITIRKVYQRAVVTPMLNLEALWREYNSFEQSVNKALAKKLID 224 .9********************************************************************************************** PP Suf 197 ekskeYmkarsvakelenltkgLkrslpsvppketeeeekqlelWkkwikwEkenpleledeellkkRilyvyeqallallfvpeiWyeaaeylee 292 +k++eYm+ar+vake+e++t+gL r psvp + ++ee kql++Wkk+i+wEk+npl++ed++ll+kR++y+yeq+l++++f+ ++W+eaa yle+ FUN_001148-T1 225 DKTREYMNARRVAKEYEAITRGLVRGNPSVPINGSSEENKQLQIWKKYIAWEKSNPLRTEDTALLTKRVVYAYEQCLQTMGFHSNVWCEAALYLEK 320 ************************************************************************************************ PP Suf 293 sske..............eeaakllerai.kalpesllLtfklaeleEsrnkiekvkeiyeklldallkelkklkeeeeeekeieklkkkltlvyi 373 s++ +e+a l+era+ ++++++lL+f++a++eE r+k++k+keiyek+l + ++ ++tlvyi FUN_001148-T1 321 VSQQlmdkgdmqgskvlsDETAGLYERAVtGLMKHNMLLYFAYADFEEGRMKFQKAKEIYEKYL--------------------ALENIDPTLVYI 396 ***9*************************99*********************************....................8999******** PP Suf 374 qymkfmrRaegikaaRkvFkkaRkkkrltyevyvasAlleyhcskdkkvalkifelGlkkFsedeeyilkYldfLislnddnnirvlFervvekle 469 qymkf+rR+e+ik++R +Fk+aR+++r++++v++++Al+ey+cskdk++a+kifelGlkk++++ +y+l+Y+d+L++lnddnn+rvlFe+v++++ FUN_001148-T1 397 QYMKFARRSESIKESRAIFKRAREDSRTNFHVFISAALMEYYCSKDKSIAFKIFELGLKKHMNETDYVLAYVDYLSHLNDDNNTRVLFEKVLSSMP 492 *********************************************************************************************977 PP Suf 470 eekeklkeiykkfieyeskfgdlssvlklekrlaeafpe...ekeielfvdRyklqdlnpikkeel 532 +ek +++++ kf+e+e ++gdl+s++k+e+r ea+ e ei+++vdRyk+ dl p++ el FUN_001148-T1 493 NEK--ASDVWGKFLEFEGTCGDLASLVKVENRKLEAYREeleGLEISVLVDRYKYLDLFPCTPLEL 556 666..8********************************9887789****************99886 PP >> HAT_PRP39_N PRP39 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.4 2.7 8e-30 2.3e-26 5 167 .. 40 208 .. 37 211 .. 0.92 2 ! 7.9 0.3 0.0014 4.1 120 148 .. 261 289 .. 229 307 .. 0.69 3 ! 14.0 3.1 2e-05 0.057 50 153 .. 268 385 .. 266 388 .. 0.74 4 ! 13.3 0.6 3.2e-05 0.091 53 123 .. 362 427 .. 356 441 .. 0.75 5 ! 21.7 0.0 8.7e-08 0.00025 64 154 .. 443 526 .. 432 533 .. 0.85 Alignments for each domain: == domain 1 score: 93.4 bits; conditional E-value: 8e-30 HAT_PRP39_N 5 kavkenpedfnaWtkLlqyveqendiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYleflketleked 100 + ++++p d ++W L++++++ + +e+ r +++ +++P Yw+ Y + e +++n+e++e+++++++ ++ l++dlW Yl+++++t + FUN_001148-T1 40 TRLQNHPYDTESWGVLIREAQS-TPLETSRVLCEKLVRRFPNAGRYWRLYIEQEIKNNNYEQVEKLFQKCLIKV-LNIDLWKCYLSYVRDTK-CSL 132 56899**************985.67***********************************************99.89************985.678 PP HAT_PRP39_N 101 peseekirelferavaavGldfrsdklWdkYief....e.....keqkelkkvtaiydrilkiptqkyerhfekfk 167 p+ ++k+ +++e a+++vG df+s ++W ++++f e e++++ ++ ++y+r++ +p+ ++e +++++ FUN_001148-T1 133 PNFRDKMLQAYEFALEKVGVDFNSYQIWIDFVNFlktgEavgsyAENRKIITIRKVYQRAVVTPMLNLEALWREYN 208 99********************************65551444447899999********************99996 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0014 HAT_PRP39_N 120 ldfrsdklWdkYiefekeqkelkkvtaiy 148 + + ++W+kYi++ek++ ++ ta++ FUN_001148-T1 261 EENKQLQIWKKYIAWEKSNPLRTEDTALL 289 55667799********9886433333333 PP == domain 3 score: 14.0 bits; conditional E-value: 2e-05 HAT_PRP39_N 50 YwkkYadlekr........kgnlekaeevyergvkaiplsvdlWlh...Yleflketlek.ed....peseekirelferavaavGldfrsdklWd 129 wkkY +ek+ + +++++ ye++++++ + ++W + Yle + ++l + d + +++ l+erav+ Gl + l FUN_001148-T1 268 IWKKYIAWEKSnplrtedtALLTKRVVYAYEQCLQTMGFHSNVWCEaalYLEKVSQQLMDkGDmqgsKVLSDETAGLYERAVT--GLMKHNMLLYF 361 6*******998443332212235788899***************97444666666655431332221333478889*****96..78888999*** PP HAT_PRP39_N 130 kYiefekeqkelkkvtaiydrilk 153 +Y +fe+ + +++k+ +iy++ l+ FUN_001148-T1 362 AYADFEEGRMKFQKAKEIYEKYLA 385 ********************9987 PP == domain 4 score: 13.3 bits; conditional E-value: 3.2e-05 HAT_PRP39_N 53 kYadlekrkgnlekaeevyergvkaiplsvdlWlhYleflketlekedpeseekirelferavaavGldfr 123 Yad+e+ + +ka+e+ye+ ++ ++d l Y++++k + ++es ++ r++f+ra + ++f+ FUN_001148-T1 362 AYADFEEGRMKFQKAKEIYEKYLALE--NIDPTLVYIQYMKFAR---RSESIKESRAIFKRAREDSRTNFH 427 6********************98765..4666666666665432...345678889999999887777665 PP == domain 5 score: 21.7 bits; conditional E-value: 8.7e-08 HAT_PRP39_N 64 lekaeevyergvkaiplsvdlWlhYleflketlekedpeseekirelferavaavGldfrsdklWdkYiefekeqkelkkvtaiydrilki 154 ++ a +++e g+k+ ++ d l Y+++l + + +++ r lfe+ ++++ ++ sd +W k++efe + ++l +++++ +r l+ FUN_001148-T1 443 KSIAFKIFELGLKKHMNETDYVLAYVDYLSHLND------DNNTRVLFEKVLSSMPNEKASD-VWGKFLEFEGTCGDLASLVKVENRKLEA 526 455789***********************97532......3578***********9998775.8*******************99988765 PP >> HAT_PRP39_C PRP39 C-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 2.8 5.9e-08 0.00017 27 87 .. 84 145 .. 79 154 .. 0.80 2 ! 9.5 0.5 0.00048 1.4 59 108 .. 157 216 .. 137 240 .. 0.68 3 ! 46.5 5.4 1.8e-15 5.2e-12 21 139 .] 262 404 .. 257 404 .. 0.81 4 ! 5.7 0.3 0.0069 20 62 98 .. 395 429 .. 390 465 .. 0.64 5 ! 7.7 0.0 0.0018 5 30 68 .. 466 506 .. 456 525 .. 0.81 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 5.9e-08 HAT_PRP39_C 27 nWrkYldfeeeegdkerivvlyERcliacalyeefWlrYarylesk..seeearnvyeracti 87 Wr Y++ e++++++e+++ l+ +cli + + ++W Y +y+++ s + r+ + +a+++ FUN_001148-T1 84 YWRLYIEQEIKNNNYEQVEKLFQKCLIKVLNI-DLWKCYLSYVRDTkcSLPNFRDKMLQAYEF 145 6**************************98766.79*******987512445666666666555 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00048 HAT_PRP39_C 59 eefWlrYaryl..........eskseeearnvyeractihlpkkpeirlawaafeEkqgn 108 ++W+ ++++l e++++ ++r+vy+ra+ + + + +++ ++ fe + ++ FUN_001148-T1 157 YQIWIDFVNFLktgeavgsyaENRKIITIRKVYQRAVVTPMLNLEALWREYNSFEQSVNK 216 46899999999666555544444556679*******887666666666666666655443 PP == domain 3 score: 46.5 bits; conditional E-value: 1.8e-15 HAT_PRP39_C 21 eeaqlknWrkYldfeeee........gdkerivvlyERcliacalyeefWlrYaryles..ks..........e...eearnvyeractihlpkkp 93 e++ql+ W+kY+ +e+++ ++r+v yE+cl ++ +++++W++ a yle+ ++ + +e+ +yera+t ++++ FUN_001148-T1 262 ENKQLQIWKKYIAWEKSNplrtedtaLLTKRVVYAYEQCLQTMGFHSNVWCEAALYLEKvsQQlmdkgdmqgsKvlsDETAGLYERAVTGLMKHNM 357 789*************99777655444678***************************652221222233333313447899*************** PP HAT_PRP39_C 94 eirlawaafeEkqgnveeAreilealee.klpgllevilrlinlerR 139 + +a+a feE + ++++A+ei+e+++ + + + v+++++++ rR FUN_001148-T1 358 LLYFAYADFEEGRMKFQKAKEIYEKYLAlENIDPTLVYIQYMKFARR 404 ************************97652666888899999999998 PP == domain 4 score: 5.7 bits; conditional E-value: 0.0069 HAT_PRP39_C 62 WlrYaryles.kseeearnvyeractihlpkkpeirla 98 +++Y+++ ++ +s++e r++++ra + +++++++ FUN_001148-T1 395 YIQYMKFARRsESIKESRAIFKRARE---DSRTNFHVF 429 45666666541567888888888865...344444433 PP == domain 5 score: 7.7 bits; conditional E-value: 0.0018 HAT_PRP39_C 30 kYldfeeeegdkerivvlyERcliaca..lyeefWlrYary 68 +Y+d+ + +d+++++vl+E++l ++ +++W ++ ++ FUN_001148-T1 466 AYVDYLSHLNDDNNTRVLFEKVLSSMPneKASDVWGKFLEF 506 7**********************776511567899998887 PP >> HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 1.3 1.8e-07 0.00052 6 107 .. 39 128 .. 35 145 .. 0.85 2 ! 16.9 0.7 2e-06 0.0057 17 108 .. 119 215 .. 118 231 .. 0.72 3 ! 24.1 3.4 1.3e-08 3.6e-05 12 154 .. 262 417 .. 259 418 .. 0.79 4 ! 15.2 0.2 6.9e-06 0.02 74 155 .. 371 453 .. 364 460 .. 0.90 5 ! 12.5 0.0 4.6e-05 0.13 98 156 .. 465 524 .. 446 529 .. 0.81 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1.8e-07 HAT_Syf1_CNRKL1_N 6 EeeilrnpysvkaWlrYiehkkkkksleelalvyeRAlkelprsyklWkaYlklrvkqvkkknpvkkeeeyekvnnlferalvllnkmpriW 97 E+ ++ +py++++W i+ ++++le+ ++ e+ ++++p+ + W+ Y+++ ++k+ ++ye+v++lf+++l+ + +++ +W FUN_001148-T1 39 ETRLQNHPYDTESWGVLIREA-QSTPLETSRVLCEKLVRRFPNAGRYWRLYIEQ---EIKN-------NNYEQVEKLFQKCLIKVLNID-LW 118 888999************987.67899*************************97...4444.......4699***********999986.9* PP HAT_Syf1_CNRKL1_N 98 ldYlefllkq 107 Yl+++ + FUN_001148-T1 119 KCYLSYVRDT 128 ****998764 PP == domain 2 score: 16.9 bits; conditional E-value: 2e-06 HAT_Syf1_CNRKL1_N 17 kaWlrYiehkkkkks..leelalvyeRAlkelp...rsyklWkaYlklrvkqvkkknpvkkeeeyekvnnlferalvl.lnkmpriWldYle 102 k++l+Y++ +k + + +++ ye Al+++ +sy++W +++++ ++ + +++++++ +++++++ra+v+ + ++ +W +Y + FUN_001148-T1 119 KCYLSYVRDTKCSLPnfRDKMLQAYEFALEKVGvdfNSYQIWIDFVNFLKTG-EAVGSYAENRKIITIRKVYQRAVVTpMLNLEALWREYNS 209 55666665443332211345567899999998644479********996554.44555567889999********9987999********99 PP HAT_Syf1_CNRKL1_N 103 fllkqk 108 f ++ + FUN_001148-T1 210 FEQSVN 215 987654 PP == domain 3 score: 24.1 bits; conditional E-value: 1.3e-08 HAT_Syf1_CNRKL1_N 12 npysvkaWlrYiehkkkkks........leelalvyeRAlkelprsyklWka...Ylklrvkqvkkknpvk.keeeyekvnnlferalvlln 91 ++++++ W +Yi ++k++ ++++++ ye l+++ + ++W + Yl+ +q+ +k ++ ++ +++ l+era++ l FUN_001148-T1 262 ENKQLQIWKKYIAWEKSNPLrtedtallTKRVVYAYEQCLQTMGFHSNVWCEaalYLEKVSQQLMDKGDMQgSKVLSDETAGLYERAVTGLM 353 567899*******99864332222333345567789**************64445***999999988766614556678899******9888 PP HAT_Syf1_CNRKL1_N 92 kmp.riWldYlefllkqkkvtktrrtfdraLralpitqheriWelylkfaksae.getavrvyrr 154 k ++ Y +f + k k+++++++ L i + + ++ +y+kfa+++e + + +++r FUN_001148-T1 354 KHNmLLYFAYADFEEGRMKFQKAKEIYEKYLALENI-DPTLVYIQYMKFARRSEsIKESRAIFKR 417 87725799***********************87776.6789*********996636888888988 PP == domain 4 score: 15.2 bits; conditional E-value: 6.9e-06 HAT_Syf1_CNRKL1_N 74 eeyekvnnlferalvllnkmpr.iWldYlefllkqkkvtktrrtfdraLralpitqheriWelylkfaksaegetavrvyrry 155 +++k+++++e+ l+l n p ++++Y++f + +++ + r +f ra + h i ++ +++ s++++ a ++++ FUN_001148-T1 371 MKFQKAKEIYEKYLALENIDPTlVYIQYMKFARRSESIKESRAIFKRAREDSRTNFHVFISAALMEYYCSKDKSIAFKIFELG 453 6899************999996369***********************99999999999**********99999999999755 PP == domain 5 score: 12.5 bits; conditional E-value: 4.6e-05 HAT_Syf1_CNRKL1_N 98 ldYlefllkqkkvtktrrtfdraLralpitqheriWelylkfaksae.getavrvyrryl 156 l Y+++l + ++ +tr f++ L ++p + + +W +l+f + + v+v +r l FUN_001148-T1 465 LAYVDYLSHLNDDNNTRVLFEKVLSSMPNEKASDVWGKFLEFEGTCGdLASLVKVENRKL 524 6899999999999*****************************988653567777777766 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 3.1 8.9e+03 27 42 .. 41 56 .. 38 57 .. 0.83 2 ? 4.0 0.0 0.056 1.6e+02 21 42 .. 68 89 .. 64 90 .. 0.87 3 ! 6.3 0.0 0.0097 27 3 30 .. 84 111 .. 82 123 .. 0.84 4 ? -2.3 0.0 5.9 1.7e+04 17 37 .. 182 202 .. 173 207 .. 0.67 5 ! 9.0 0.1 0.0013 3.7 3 36 .. 359 392 .. 358 401 .. 0.83 6 ? 2.5 0.0 0.17 4.8e+02 4 32 .. 395 423 .. 391 435 .. 0.86 7 ? 1.6 0.0 0.34 9.6e+02 10 42 .. 436 468 .. 428 470 .. 0.84 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 3.1 TPR_14 27 alaldPddpeawlala 42 l+ +P d+e w l+ FUN_001148-T1 41 RLQNHPYDTESWGVLI 56 5899*******98886 PP == domain 2 score: 4.0 bits; conditional E-value: 0.056 TPR_14 21 lelleralaldPddpeawlala 42 + l e++++++P+ ++w++++ FUN_001148-T1 68 RVLCEKLVRRFPNAGRYWRLYI 89 56889**************997 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0097 TPR_14 3 awlalarallalGdpdeAlelleralal 30 w+++++ + +++++++ ++l++++l + FUN_001148-T1 84 YWRLYIEQEIKNNNYEQVEKLFQKCLIK 111 69**********************9864 PP == domain 4 score: -2.3 bits; conditional E-value: 5.9 TPR_14 17 pdeAlelleralaldPddpea 37 +++++ra+ + + ea FUN_001148-T1 182 IITIRKVYQRAVVTPMLNLEA 202 556789999998776666544 PP == domain 5 score: 9.0 bits; conditional E-value: 0.0013 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpe 36 ++ a+a++++ + ++++A e++e++lal+ dp FUN_001148-T1 359 LYFAYADFEEGRMKFQKAKEIYEKYLALENIDPT 392 5789***********************9765553 PP == domain 6 score: 2.5 bits; conditional E-value: 0.17 TPR_14 4 wlalarallalGdpdeAlelleralaldP 32 +++++++ ++ +e +++++ra + FUN_001148-T1 395 YIQYMKFARRSESIKESRAIFKRAREDSR 423 78999*******************88655 PP == domain 7 score: 1.6 bits; conditional E-value: 0.34 TPR_14 10 allalGdpdeAlelleralaldPddpeawlala 42 + +d + A +++e +l+++ +++++ la++ FUN_001148-T1 436 EYYCSKDKSIAFKIFELGLKKHMNETDYVLAYV 468 5777888999**************999998886 PP >> HAT_Syf1_CNRKL1_C Pre-mRNA-splicing factor Syf1/CRNKL1 C-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.5 0.5 0.003 8.6 164 215 .. 77 125 .. 65 153 .. 0.85 2 ! 4.9 0.4 0.0045 13 9 80 .. 157 233 .. 151 249 .. 0.75 3 ! 14.9 2.7 4.2e-06 0.012 189 272 .. 339 420 .. 293 437 .. 0.74 4 ! 7.4 0.0 0.00077 2.2 152 237 .. 446 526 .. 428 532 .. 0.72 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.003 HAT_Syf1_CNRKL1_C 164 kypvakeiWnlYlskfvkRkggskleraRdlfeqalekaPakeakklyllya 215 ++p+a W lY+++ +k ++ e++ lf+++l k+ + + k yl y FUN_001148-T1 77 RFPNAGRYWRLYIEQEIKNNNY---EQVEKLFQKCLIKVLNIDLWKCYLSYV 125 799999*********9988777...777789*****9999999999999986 PP == domain 2 score: 4.9 bits; conditional E-value: 0.0045 HAT_Syf1_CNRKL1_C 9 selwvefakfyeekg.........dlenarkifekavkveykkvdelaevwcewaelelrkenfdealevlkrataepkrk 80 ++w++f +f ++ + ++ + rk++++av + +l ++w e+ +e n a +++ t e+ ++ FUN_001148-T1 157 YQIWIDFVNFLKTGEavgsyaenrKIITIRKVYQRAVVTPML---NLEALWREYNSFEQSV-NKALAKKLIDDKTREYMNA 233 68999999999888778888888899999*******998865...5677899999998544.4556677777777766554 PP == domain 3 score: 14.9 bits; conditional E-value: 4.2e-06 HAT_Syf1_CNRKL1_C 189 eraRdlfeqalekaPakeakklyllyakleeeyGlarramkiyeratkavededklemyeiyiakaaelfGltktReiyeraie 272 + + l+e+a+ k+ ly +ya++ee + ++a +iye+ a e+ d + +y y++ a + + ++R i++ra e FUN_001148-T1 339 DETAGLYERAVTGL-MKHNMLLYFAYADFEEGRMKFQKAKEIYEKYL-ALENIDPTLVYIQYMKFARRSESIKESRAIFKRARE 420 45667899999876.56677899999999999999999999999865.788889999999999999999999999999999865 PP == domain 4 score: 7.4 bits; conditional E-value: 0.00077 HAT_Syf1_CNRKL1_C 152 sfkvyergvelFkypvakeiWnlYlskfvkRkggskleraRdlfeqalekaPakeakklyllyakleeeyGlarramkiyeratka 237 +fk++e g++ + + ++ +Y+ + + + + + +R lfe+ l+++P+++a ++ ++ ++e ++G +k+ +r +a FUN_001148-T1 446 AFKIFELGLKK--HMNETDYVLAYVDYLSHLNDD---NNTRVLFEKVLSSMPNEKASDVWGKFLEFEGTCGDLASLVKVENRKLEA 526 57777777663..344444444444444443444...5689999999999999999999999999999999777777777776655 PP >> NRDE-2 NRDE-2, necessary for RNA interference # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.2 0.1 0.0092 26 95 138 .. 72 112 .. 67 117 .. 0.86 2 ! 8.1 0.4 0.00061 1.7 71 139 .. 216 305 .. 148 318 .. 0.70 3 ? 0.3 0.1 0.14 4.1e+02 46 117 .. 334 404 .. 308 425 .. 0.66 4 ! 6.0 0.0 0.0026 7.4 52 117 .. 445 509 .. 440 535 .. 0.85 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0092 NRDE-2 95 eevlkenpesieLWkeyLdfrqsnfasfsveevkevfleclkal 138 e+++++ p+ + W+ y++ +++ + ++e+v ++f++cl ++ FUN_001148-T1 72 EKLVRRFPNAGRYWRLYIEQEIK---NNNYEQVEKLFQKCLIKV 112 5788888999999*****98888...788***********9655 PP == domain 2 score: 8.1 bits; conditional E-value: 0.00061 NRDE-2 71 erLllgllk.egekiwdskklakkWeevlk...............enpesieLWkeyLdfrqsnfasfs.....veevkevfleclkals 139 + L +l++ ++ ++ +++ak++e++++ e+++++++Wk+y+ ++ sn + + ++v+ ++++cl+++ FUN_001148-T1 216 KALAKKLIDdKTREYMNARRVAKEYEAITRglvrgnpsvpingssEENKQLQIWKKYIAWEKSNPLRTEdtallTKRVVYAYEQCLQTMG 305 5555555541345668888999999999999999999999999998899************99865543222225677778888888765 PP == domain 3 score: 0.3 bits; conditional E-value: 0.14 NRDE-2 46 kkalaeiklsilekAlkknksnpdrerLllgllkegekiwdskklakkWeevlk.enpesieLWkeyLdfrqs 117 +k l++ + ++e+A+ +++ L+ ++ + e ++ +k+++ +e++l+ en + + ++++y++f + FUN_001148-T1 334 SKVLSDETAGLYERAVTGL--MKHNMLLYFAYADFEEGRMKFQKAKEIYEKYLAlENIDPTLVYIQYMKFARR 404 4556666667777777666..5666667777777777777777777777777775555667777777777665 PP == domain 4 score: 6.0 bits; conditional E-value: 0.0026 NRDE-2 52 iklsilekAlkknksnpdrerLllgllkegekiwdskklakkWeevlk..enpesieLWkeyLdfrqs 117 i +i+e lkk+ ++++ +l++ + +++ d+++++ +e+vl+ n++ ++W ++L+f+ + FUN_001148-T1 445 IAFKIFELGLKKH---MNETDYVLAYVDYLSHLNDDNNTRVLFEKVLSsmPNEKASDVWGKFLEFEGT 509 5667888999999...899999**************************444457899********866 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.16 4.4e+02 41 58 .. 40 57 .. 38 62 .. 0.88 2 ? 2.0 0.0 0.082 2.3e+02 93 148 .. 54 109 .. 52 115 .. 0.92 3 ? 8.3 0.0 0.00094 2.7 79 146 .. 384 452 .. 359 465 .. 0.80 4 ? 0.5 0.0 0.24 6.8e+02 65 112 .. 442 490 .. 438 499 .. 0.70 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.16 TPR_CcmH_CycH 41 tkLqkepddatgWllLGr 58 t+Lq++p d + W +L r FUN_001148-T1 40 TRLQNHPYDTESWGVLIR 57 89***********99865 PP == domain 2 score: 2.0 bits; conditional E-value: 0.082 TPR_CcmH_CycH 93 aLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnafeqgdyeeAiaaWqkml 148 +L+++ + + l+ ++ l +kl+++ p+ r + l+ +++++++ye+ + +qk l FUN_001148-T1 54 VLIREAQSTPLETSRVLCEKLVRRFPNAGRYWRLYIEQEIKNNNYEQVEKLFQKCL 109 7899999999999**********************************999999865 PP == domain 3 score: 8.3 bits; conditional E-value: 0.00094 TPR_CcmH_CycH 79 lapnnteiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnlralsllAfnaf.eqgdyeeAiaaWqk 146 la +n + l Y q + + e++k+++ + k++ ++++tn +++ A++++ +d + A + ++ FUN_001148-T1 384 LALENIDPTLVYIQYMKFARRSESIKESRAIFKRAREDSRTNFHVFISAALMEYyCSKDKSIAFKIFEL 452 4456888899************************************99998765157788888888875 PP == domain 4 score: 0.5 bits; conditional E-value: 0.24 TPR_CcmH_CycH 65 daetAiqAfekAlklapnnteiklsYaqaLmlsgdeedlk.kAeelLkk 112 d + A++ fe lk + n+t++ l Y++ L +d+++++ e++L++ FUN_001148-T1 442 DKSIAFKIFELGLKKHMNETDYVLAYVDYLSHLNDDNNTRvLFEKVLSS 490 55667777888888899999**********9999987654123444444 PP >> Mad3_BUB1_I Mad3/BUB1 homology region 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.2 0.29 8.3e+02 20 82 .. 119 173 .. 98 192 .. 0.59 2 ? 9.9 4.7 0.00033 0.94 15 121 .. 262 382 .. 254 384 .. 0.74 3 ? 0.3 0.0 0.31 8.8e+02 97 122 .. 393 418 .. 388 419 .. 0.83 4 ? -3.5 0.0 4.6 1.3e+04 15 32 .. 460 477 .. 447 489 .. 0.61 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.29 Mad3_BUB1_I 20 elwlryikwleesypqsgkesgllellerclkkfkdderYknDpRylklwlkyaelveeprei 82 + +l+y++ ++ s+p+ ++++l+ +e +l+k+ D ++w+ ++++ + + + FUN_001148-T1 119 KCYLSYVRDTKCSLPN--FRDKMLQAYEFALEKVG------VDFNSYQIWIDFVNFLKTGEAV 173 4556666666666666..45566666666555542......2333334555555555555555 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00033 Mad3_BUB1_I 15 gdDPLelwlryikwleesypq....sgkesgllellerclkkfkdd.erYknDpRylklw.lkyaelv.........eepreifkflaskkiGtkl 95 + L++w +yi w +++ + + ++++ +e+cl+++ + + + + yl+ + ++++ +e + +++ a + + FUN_001148-T1 262 ENKQLQIWKKYIAWEKSNPLRtedtALLTKRVVYAYEQCLQTMGFHsNVWCEAALYLEKVsQQLMDKGdmqgskvlsDETAGLYER-AVTGLMKHN 356 5678999******9888876644443446677788999999986542677888888864414455543666988885666666665.567888999 PP Mad3_BUB1_I 96 alfYeeyAellekkgrfkeAdevyel 121 l+Y +yA++ e + +f++A+e+ye+ FUN_001148-T1 357 MLLYFAYADFEEGRMKFQKAKEIYEK 382 9***********************86 PP == domain 3 score: 0.3 bits; conditional E-value: 0.31 Mad3_BUB1_I 97 lfYeeyAellekkgrfkeAdevyelG 122 l Y++y ++ +++ +ke++++++++ FUN_001148-T1 393 LVYIQYMKFARRSESIKESRAIFKRA 418 68999999999999999999999875 PP == domain 4 score: -3.5 bits; conditional E-value: 4.6 Mad3_BUB1_I 15 gdDPLelwlryikwlees 32 D ++++y+++l++ FUN_001148-T1 460 ETDYVLAYVDYLSHLNDD 477 346666666666666554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (724 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 808 (0.0316305); expected 510.9 (0.02) Passed bias filter: 512 (0.0200431); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.40u 0.41s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 6908.98 // Query: FUN_001150-T1 [L=208] Description: FUN_001150 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.1e-31 107.1 0.1 1.4e-30 106.5 0.1 1.3 1 LOH1CR12 Tumour suppressor protein Domain annotation for each model (and alignments): >> LOH1CR12 Tumour suppressor protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.5 0.1 5.5e-35 1.4e-30 3 130 .. 76 203 .. 74 204 .. 0.98 Alignments for each domain: == domain 1 score: 106.5 bits; conditional E-value: 5.5e-35 LOH1CR12 3 lPvlkeviskrtsrtneklekldsqqllrlctRlqehlalcakavaadqnklverikeveasvitLfaelrerqkryakyaeqlskvnelsddlsr 98 P++++ is t+r+ e l+k+d ++ l +c+R+ +hl +ca+ v++dqn l r++ev+a ++ + er kr + a ql kv+e++++l+r FUN_001150-T1 76 YPLIRGTISATTAREFEFLQKFDLRPCLLMCLRYENHLRQCADVVSFDQNMLSSRVREVDAHSAVVLRRVSERFKRLSHEAGQLRKVEEMNANLKR 171 59********************************************************************************************** PP LOH1CR12 99 iqilleeivpllealnelLdeeeRLePlslkp 130 i+ l+ vp +e+ln++L+e eRLe +sl+p FUN_001150-T1 172 IDANLKRLVPTMERLNNMLPEGERLERFSLEP 203 *****************************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1527 (0.0597769); expected 510.9 (0.02) Passed bias filter: 977 (0.0382462); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2049.05 // Query: FUN_001151-T1 [L=478] Description: FUN_001151 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-16 61.0 0.5 3.8e-16 60.0 0.5 1.5 1 FERM_M FERM central domain 7.3e-14 51.9 0.0 1.5e-13 50.9 0.0 1.5 1 FERM_N FERM N-terminal domain 4.7e-12 46.0 18.6 1.2e-11 44.7 18.6 1.8 1 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 0.0011 19.6 7.4 0.0027 18.4 7.4 1.6 1 TerY_C TerY-C metal binding domain ------ inclusion threshold ------ 0.014 15.7 17.2 0.031 14.7 17.2 1.6 1 Prok-RING_4 Prokaryotic RING finger family 4 0.038 14.9 0.1 0.038 14.9 0.1 2.3 3 FERM_C FERM C-terminal PH-like domain 0.66 10.8 22.8 0.42 11.4 19.8 2.2 2 zf-RING_2 Ring finger domain Domain annotation for each model (and alignments): >> FERM_M FERM central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.0 0.5 1e-19 3.8e-16 3 117 .] 84 198 .. 82 198 .. 0.94 Alignments for each domain: == domain 1 score: 60.0 bits; conditional E-value: 1e-19 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx RF FERM_M 3 esklqdevtrellYlQlkrdllegrlpcse...eeallLAaLqlqaelgdyssesheseylslesflpkq.llkklkskelekrvleahkklrgls 94 +++lq+e+tr+++Yl lk+ + eg+l+ s+ ++ ++L aL+ q+e g++s+e ++ + +s+lp + +++ k+++l+k v+ +h +l ++s FUN_001151-T1 84 PQELQQEITRHQYYLTLKNFISEGKLDLSSlqvKTIARLCALISQIECGNFSQE----RVAKYSSYLPLSiYNEYAKTSDLQKDVAIEHARLMNCS 175 789***********************9998899******************988....777789*****977778899****************** PP xxxxxxxxxxxxxxxxxxxxxxx RF FERM_M 95 aeeAklkylqiaqslptyGvelF 117 a+e k+++l+ia+ ++ yG+e+F FUN_001151-T1 176 ASESKIEFLHIACGIQGYGIEIF 198 *********************98 PP >> FERM_N FERM N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.9 0.0 4e-17 1.5e-13 6 62 .. 10 66 .. 6 68 .. 0.92 Alignments for each domain: == domain 1 score: 50.9 bits; conditional E-value: 4e-17 FERM_N 6 gtklefevqkkatgqelLdqVckhlnlkEkdyFGLqfldsksehrWLdlekklekqa 62 g +e+ + k+a gqe+Ld+Vc++l l+E dyFGL f + k++++WL+l+++ + q+ FUN_001151-T1 10 GIIHEIFLSKNAVGQECLDKVCEKLKLVERDYFGLKFGGAKGVRFWLNLRNPMSSQL 66 556788899*******************************************99997 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 18.6 3.3e-15 1.2e-11 2 47 .. 426 468 .. 425 470 .. 0.95 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 3.3e-15 zf-C3HC4_3 2 eeeCviClerernvvllpCgHlclCeeCaeklrkkkkCpiCrqkie 47 + C+iC+++e+ ++++pCgH+++C +C+ + k+Cp+Cr++i+ FUN_001151-T1 426 ARICQICMDNEVATAFCPCGHVVCCADCSAMC---KECPLCRSQIT 468 578*****************************...*********98 PP >> TerY_C TerY-C metal binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 7.4 7.3e-07 0.0027 63 115 .. 415 470 .. 403 474 .. 0.83 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 7.3e-07 TerY_C 63 dlkvntsellGapgcPhc.GnatalalcgcGkllcisdeee..atcPwcekevalg 115 +lk+ +l a c c n++a a+c cG+++c d + ++cP c ++++++ FUN_001151-T1 415 KLKIMVRHLQDARICQICmDNEVATAFCPCGHVVCCADCSAmcKECPLCRSQITYA 470 5688899999*****9984699**************997652278*******9987 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 17.2 8.4e-06 0.031 1 43 [. 429 470 .. 429 473 .. 0.80 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 8.4e-06 Prok-RING_4 1 CvlcgreetkivlspCgHlvC.keCfdssdfs.aCPiCrrrvdad 43 C +c +e + pCgH+vC +C+ CP+Cr+++ + FUN_001151-T1 429 CQICMDNEVATAFCPCGHVVCcADCSAM---CkECPLCRSQITYA 470 99*****************761566544...337******99765 PP >> FERM_C FERM C-terminal PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 3.8 1.4e+04 44 65 .. 79 98 .. 77 103 .. 0.60 2 ? -3.8 0.0 7 2.5e+04 8 21 .. 187 200 .. 185 203 .. 0.80 3 ? 14.9 0.1 1e-05 0.038 24 89 .. 240 303 .. 205 307 .. 0.78 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 3.8 FERM_C 44 kfliklrkeedkkkeetleFkl 65 kf++k+++ +++ + ++++l FUN_001151-T1 79 KFFVKPQELQQE--ITRHQYYL 98 799999933333..33455554 PP == domain 2 score: -3.8 bits; conditional E-value: 7 FERM_C 8 lLGvsakGilvyek 21 G++ Gi+++++ FUN_001151-T1 187 ACGIQGYGIEIFHG 200 5699999****987 PP == domain 3 score: 14.9 bits; conditional E-value: 1e-05 FERM_C 24 kipknlFpWseirkisfkrkkfliklrkeedkkkeetleFklessrackslwklcveqhkffrlrk 89 ++++++ + ++++++s++++ f++ + ++ + ++k++s++ + l++ e+h+f++++ FUN_001151-T1 240 RTLEKRVSFEDVSTVSYNNRSFTVVHG--GTGPQAQRDTYKMKSESDAVALFRTFTEYHTFYQCNT 303 33677788899************9888..5555556679***********************9875 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.3 4.6e+03 26 36 .. 23 33 .. 19 35 .. 0.76 2 ? 11.4 19.8 0.00012 0.42 3 44 .] 429 464 .. 427 464 .. 0.88 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.3 zf-RING_2 26 hkeCldkwlrt 36 ++eCldk++++ FUN_001151-T1 23 GQECLDKVCEK 33 68999998765 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00012 zf-RING_2 3 CpiCleeleeeekvivlpCgHv.fhkeCldkwlrtsstCPlCr 44 C iC+ ++e + +pCgHv ++ +C + ++CPlCr FUN_001151-T1 429 CQICM---DNEVATAFCPCGHVvCCADC----SAMCKECPLCR 464 99**8...8889999******9899999....57899*****9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (478 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1075 (0.0420826); expected 510.9 (0.02) Passed bias filter: 501 (0.0196124); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4728.76 // Query: FUN_001152-T1 [L=138] Description: FUN_001152 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-08 32.5 3.6 1e-07 32.0 3.6 1.3 1 Yae1_N Essential protein Yae1, N terminal Domain annotation for each model (and alignments): >> Yae1_N Essential protein Yae1, N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.0 3.6 4e-12 1e-07 1 39 [] 25 63 .. 25 63 .. 0.98 Alignments for each domain: == domain 1 score: 32.0 bits; conditional E-value: 4e-12 Yae1_N 1 GYreGiseGkeeglqEGfdeGfekGaelGlevGyllGvl 39 G++eG++ Gk +gl EG+ G kG ++G evG +lG++ FUN_001152-T1 25 GFKEGYETGKTQGLSEGRLLGVSKGCDIGREVGSYLGFV 63 9************************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (138 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 544 (0.0212958); expected 510.9 (0.02) Passed bias filter: 529 (0.0207086); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1370.91 // Query: FUN_001153-T1 [L=321] Description: FUN_001153 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-34 119.7 38.9 1.4e-34 119.7 38.9 1.9 2 CCDC34 Coiled-coil domain-containing protein 34 Domain annotation for each model (and alignments): >> CCDC34 Coiled-coil domain-containing protein 34 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 2.2 0.12 3e+03 65 89 .. 102 126 .. 85 133 .. 0.47 2 ! 119.7 38.9 5.6e-39 1.4e-34 2 170 .] 135 314 .. 134 314 .. 0.97 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.12 CCDC34 65 kekekkekeekekeeekkeekeeka 89 k++++k++++ +k++++++++++ + FUN_001153-T1 102 KRSSSKTTRSLSKSSTERRRTKSAS 126 2222222233333333333333333 PP == domain 2 score: 119.7 bits; conditional E-value: 5.6e-39 CCDC34 2 lsayeeWllaKek...ekkeekkqeekkekeekekeeeekeerkelaeekykeWlekKkeqekkekkekekkekeekekeeekkeekeekakekyk 94 ls++e+Wl++K++ ek ++++ +++kekeeke e++++ee ++ +e + +Wle+K++ ++e+k+k +e+ e+ek+e+ ++ ++eka +y+ FUN_001153-T1 135 LSPWESWLVKKSAenrEKVKQQRLQNRKEKEEKEIEQRKREEELKRGNEVIAKWLENKRKTSAEERKKKLLQEQLEQEKRESSNRFITEKATVEYN 230 79********9999888889999999999999999************************************************************* PP CCDC34 95 eWlkkKkeeeeekrekekeeeekkeeeeqeRkekaeeafeeWlkkvknkpkpvplnqgldslr........gtpspsyiNPipW 170 +Wl++Kk +e+ek++k++ e++ k+e+e +Rk ++eea+++W+ k+++kpk+v+++ g++ + ++p+psy+NP+pW FUN_001153-T1 231 HWLERKKAQEKEKKRKDEVEARVKKEKEVQRKLDNEEAYSRWIAKANEKPKSVYNSFGYTGGMmmgfyewgSYPAPSYCNPVPW 314 ************************************************************************************ PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4376 (0.171306); expected 510.9 (0.02) Passed bias filter: 748 (0.0292817); expected 510.9 (0.02) Passed Vit filter: 168 (0.00657663); expected 25.5 (0.001) Passed Fwd filter: 45 (0.0017616); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.49u 0.39s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 3025.26 // Query: FUN_001154-T1 [L=305] Description: FUN_001154 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-81 273.8 7.6 2e-81 273.6 7.6 1.0 1 DUF92 Integral membrane protein DUF92 ------ inclusion threshold ------ 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 FAM176 FAM176 family 0.55 10.7 0.0 0.55 10.7 0.0 2.8 3 Borrelia_P13 Borrelia membrane protein P13 0.56 11.0 0.1 0.56 11.0 0.1 2.6 2 DUF3382 Domain of unknown function (DUF3382) 1.9 9.1 9.3 23 5.7 4.5 2.6 2 DUF2613 Protein of unknown function (DUF2613) 4.6 7.9 16.0 6.4 7.4 0.7 3.1 3 SPC12 Microsomal signal peptidase 12 kDa subunit (SPC Domain annotation for each model (and alignments): >> DUF92 Integral membrane protein DUF92 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 273.6 7.6 4.7e-85 2e-81 3 251 .] 24 287 .. 22 287 .. 0.91 Alignments for each domain: == domain 1 score: 273.6 bits; conditional E-value: 4.7e-85 DUF92 3 alllallayrkksLtlsGalaavlvgvlillaplglaffllllvFfllgsllTkvkkeeKakaglaeekegaRdavqVlanglvalllallyalle 98 +l+++ ++++k+sL+l+Ga+a+v+vg++++l++l ff+ ++Ffl++s+lT++k++eK+k + + +k+g+R+++qV++ng+v+++lally +++ FUN_001154-T1 24 TLVIVRHGLKKQSLDLTGAVASVIVGFVLTLSNLC--FFASCATFFLTSSKLTRYKSKEKEKLEDDFKKGGQRNWIQVFCNGGVPTILALLY-IVD 116 789999**************************888..9***********************99999999**********************7.566 PP DUF92 99 l........skellalssllllgfvaslaaalaDTlaSElGkllsk.kprlittlkkVppGtnGgVsllGllagllGslliallalllll..lak. 182 + ++ + +ss+l +++++s+a++++DT+aSE+G+++ + p+litt+ kVp GtnGg++++G++a+++G+++i+++ ++++l + FUN_001154-T1 117 VgigehpidYAKDY-ISSVLSIAILGSFACSCGDTWASEIGTAVVShAPVLITTFSKVPVGTNGGITITGTVASIVGGTVIGVA-YYITLvlV-Ma 209 67998776633333.789************************99888***********************************98.55555451.23 PP DUF92 183 .........qlklillvtlaGllGsllDSllGAtlqasvvdketgkvvekkvkesrkisGldlldNnaVNllstllga 251 q+++i++++l G+lGsl+DSllGAtlq+s++++ +++vv+k+ +++++isG +ldN+aVNl+s+ll++ FUN_001154-T1 210 vrqislitpQWPIIFIGCLGGFLGSLFDSLLGATLQYSGYCSVKKRVVNKPSSTAKHISGQPILDNHAVNLFSSLLTS 287 456678889******************************************999********************9985 PP >> FAM176 FAM176 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 7.3e-05 0.31 27 69 .. 43 85 .. 37 96 .. 0.72 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7.3e-05 FAM176 27 vlgvcvGLvltLcllViriscrkdlkklakkkkelkeeseede 69 v +v vG vltL l + sc++ + +++k + +++e+e+ e FUN_001154-T1 43 VASVIVGFVLTLSNLCFFASCATFFLTSSKLTRYKSKEKEKLE 85 789*******************988844444444333333322 PP >> Borrelia_P13 Borrelia membrane protein P13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.71 3e+03 62 86 .. 39 63 .. 15 92 .. 0.59 2 ? -0.7 3.1 0.44 1.9e+03 68 94 .. 181 207 .. 105 216 .. 0.76 3 ? 10.7 0.0 0.00013 0.55 41 95 .. 236 292 .. 223 296 .. 0.80 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.71 Borrelia_P13 62 vkkkeaavisgkvlllaGvltlaas 86 + + a+vi+g vl+l+ +a+ FUN_001154-T1 39 LTGAVASVIVGFVLTLSNLCFFASC 63 4455666777777777766666554 PP == domain 2 score: -0.7 bits; conditional E-value: 0.44 Borrelia_P13 68 avisgkvlllaGvltlaasylteiilP 94 +i+g+v + +G+ ++++y + ++l FUN_001154-T1 181 ITITGTVASIVGGTVIGVAYYITLVLV 207 456777777777777777777666654 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00013 Borrelia_P13 41 GfdvlGlililaGvikaddgivkk..keaavisgkvlllaGvltlaasylteiilPf 95 +lG +l +G+ ++ +v+k ++a+ isg+ +l + l +s lt+i +P+ FUN_001154-T1 236 FDSLLGATLQYSGYCSVKKRVVNKpsSTAKHISGQPILDNHAVNLFSSLLTSITMPY 292 34689**********7776666553378899************************97 PP >> DUF3382 Domain of unknown function (DUF3382) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.2 0.74 3.1e+03 13 27 .. 40 54 .. 37 62 .. 0.58 2 ? 11.0 0.1 0.00013 0.56 36 64 .. 210 246 .. 182 273 .. 0.61 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.74 DUF3382 13 alvLalpilGlqlvl 27 + ++a++i+G+ l+l FUN_001154-T1 40 TGAVASVIVGFVLTL 54 444555555554444 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00013 DUF3382 36 t........rwglvaiavavVfvgqLlrellrqalka 64 +w +++i+++ f+g+L+ +ll +l+ FUN_001154-T1 210 VrqislitpQWPIIFIGCLGGFLGSLFDSLLGATLQY 246 1334444458*******************99888776 PP >> DUF2613 Protein of unknown function (DUF2613) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.2 0.0072 31 3 17 .. 39 53 .. 38 65 .. 0.85 2 ? 5.7 4.5 0.0054 23 4 28 .. 184 208 .. 182 216 .. 0.84 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0072 DUF2613 3 lgPaaaSaVaGivlG 17 l +a+aS+++G vl FUN_001154-T1 39 LTGAVASVIVGFVLT 53 5689*******9995 PP == domain 2 score: 5.7 bits; conditional E-value: 0.0054 DUF2613 4 gPaaaSaVaGivlGvaavfgvtavv 28 +++aS+V G+v+Gva +++++v+ FUN_001154-T1 184 TGTVASIVGGTVIGVAYYITLVLVM 208 578*************988887765 PP >> SPC12 Microsomal signal peptidase 12 kDa subunit (SPC12) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.7 0.0015 6.4 18 48 .. 39 69 .. 33 71 .. 0.91 2 ? -2.4 0.1 1.8 7.8e+03 17 27 .. 137 147 .. 126 174 .. 0.55 3 ? 7.1 5.0 0.0019 8.3 15 58 .. 179 222 .. 176 235 .. 0.94 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0015 SPC12 18 visaviafivGyitqdlkltlyiflagvvlt 48 +++av+++ivG+++ +l++++ +a+++lt FUN_001154-T1 39 LTGAVASVIVGFVLTLSNLCFFASCATFFLT 69 6789***********************9998 PP == domain 2 score: -2.4 bits; conditional E-value: 1.8 SPC12 17 lvisaviafiv 27 + i + +a+ + FUN_001154-T1 137 IAILGSFACSC 147 33334444444 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0019 SPC12 15 vilvisaviafivGyitqdlkltlyiflagvvltllvvvPpWpf 58 ++i++++a ivG + + + + ++l++ v + ++ P+Wp+ FUN_001154-T1 179 GGITITGTVASIVGGTVIGVAYYITLVLVMAVRQISLITPQWPI 222 5689***************************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (305 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1062 (0.0415737); expected 510.9 (0.02) Passed bias filter: 570 (0.0223136); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3004.05 // Query: FUN_001155-T1 [L=185] Description: FUN_001155 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-27 96.2 0.0 3e-27 95.6 0.0 1.3 1 Bcl-2 Apoptosis regulator proteins, Bcl-2 family Domain annotation for each model (and alignments): >> Bcl-2 Apoptosis regulator proteins, Bcl-2 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.6 0.0 1.2e-31 3e-27 2 100 .] 52 151 .. 51 151 .. 0.95 Alignments for each domain: == domain 1 score: 95.6 bits; conditional E-value: 1.2e-31 Bcl-2 2 rrlgdeleekheeelesmleqlelteetarelfrevaeelfsdgeinWgrvvalfafagalavklvrqg.qeelveklaewlaeyleee.ladWir 95 ++gde+++k+++++++m+++l+lt++ta+e+f++ a++lf++g inWgr+val++f++++av ++r+g ++++++++++++++ +e +a+Wi+ FUN_001155-T1 52 GEIGDEIDAKYKDQFKDMIDSLSLTPATAYETFAALARRLFRSG-INWGRIVALLCFGYEIAVTVIRRGfSGNFLRRIIRFVVDFIFNErIARWIA 146 589*****************************************.***********************825567************9999****** PP Bcl-2 96 eqgGW 100 e+gGW FUN_001155-T1 147 EHGGW 151 ***** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 702 (0.0274809); expected 510.9 (0.02) Passed bias filter: 637 (0.0249364); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1813.92 // Query: FUN_001156-T1 [L=314] Description: FUN_001156 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.077 14.1 2.3 0.26 12.4 2.3 1.9 1 DUF7699 Domain of unknown function (DUF7699) 0.12 12.8 0.3 0.22 11.9 0.3 1.4 1 T6_Ig_like T6 antigen Ig like domain 6.7 5.9 12.4 11 5.3 12.4 1.2 1 LMBR1 LMBR1-like membrane protein Domain annotation for each model (and alignments): >> DUF7699 Domain of unknown function (DUF7699) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 2.3 3.1e-05 0.26 12 82 .. 89 159 .. 86 163 .. 0.88 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 3.1e-05 DUF7699 12 vyekskkakrsakgkllgkrtvagrv.vkesygaakqqHtftievlwskgvkklpplspllvkgrnLyrlkt 82 +ye+ ++ r+a +++ + r++ g++ vke+ g++k q +++ + l +++++ ++ s l+ nL ++kt FUN_001156-T1 89 LYENRQRLARTAGDTISKLRQIEGKIlVKEKSGKQKTQTKLSTK-LKKTTIRAEKQHSRLIKMTENLEKMKT 159 78999999999999999********978**********999998.788888888888898888999999998 PP >> T6_Ig_like T6 antigen Ig like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.3 2.6e-05 0.22 15 81 .. 85 151 .. 75 179 .. 0.80 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 2.6e-05 T6_Ig_like 15 stvklykiweaeynasGdsivgfkkieGvnlsdnskptaeeinkiaadlqaGtikaldikestvsGt 81 ++ +ly + Gd+i + ++ieG l +++ + +k+++ l++ ti+a++ + t FUN_001156-T1 85 PSYTLYENRQRLARTAGDTISKLRQIEGKILVKEKSGKQKTQTKLSTKLKKTTIRAEKQHSRLIKMT 151 567889888888999*****************97777888899*************98776655554 PP >> LMBR1 LMBR1-like membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 12.4 0.0013 11 196 333 .. 44 185 .. 29 200 .. 0.78 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0013 LMBR1 196 geelkklyfkaaklkeekeeaeeeledllkevkqlkesikesdp.lrkyleeilekvPseiterlkseee....neeatekslaelhkqlikalqk 286 +++ k+ ++k + lk+ek++ +++l+++ + + ++++ + + l+++ + ++ + +i++ + e + +++ ++k+ ++l+ +k ++ FUN_001156-T1 44 SKRRKRKQTKLQALKTEKKKLQKDLKSTKEWILDENKRKASPSYtLYENRQRLARTAGDTISKLRQIEGKilvkEKSGKQKTQTKLS---TKLKKT 136 45667889999*****************99999988888888877999999999988888888844444476554444444444555...344557 PP LMBR1 287 kkrtekqwkkllkkafelediikneaskekefksse..eerrgslaeqi 333 + r+ekq ++l+k + le++++ e+s + e+ +++ +++ g+++ ++ FUN_001156-T1 137 TIRAEKQHSRLIKMTENLEKMKTGENSLRAEIAREQtaKTKDGEFSDTF 185 889999999999999999**************99987777888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (314 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2926 (0.114543); expected 510.9 (0.02) Passed bias filter: 613 (0.0239969); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.42s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3047.79 // Query: FUN_001157-T1 [L=497] Description: FUN_001157 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-51 172.3 0.0 2.9e-17 62.8 0.0 3.3 3 RRM_1 RNA recognition motif 3.4e-07 30.6 0.0 1 9.9 0.0 3.9 3 RRM_7 RNA recognition motif 1.8e-05 24.9 0.0 0.68 10.3 0.0 3.4 3 RRM_YTH1 YTH1-like RRM domain 2.5e-05 24.7 0.0 1.3 9.6 0.0 3.6 3 RNA_bind RNA binding domain 0.0087 16.7 0.0 0.85 10.3 0.0 2.7 2 RRM_10 RRM domain Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.9 0.0 5.2e-16 2.7e-12 1 64 [. 20 84 .. 20 88 .. 0.97 2 ! 59.0 0.0 8.5e-20 4.4e-16 1 66 [. 108 174 .. 108 177 .. 0.94 3 ! 62.8 0.0 5.7e-21 2.9e-17 1 70 [] 414 484 .. 414 484 .. 0.98 Alignments for each domain: == domain 1 score: 46.9 bits; conditional E-value: 5.2e-16 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd.etgrskgfafVeFedeedaekAlealngkel 64 lf+g +p++ +++L+ +F+++G+i ++++ rd t+++kg+af +F ++e a +A + l++k++ FUN_001157-T1 20 LFIGQVPRTWEDKDLRPYFEPYGQIHELTVLRDrLTRSHKGCAFLTFCSREAALNAQKDLHEKKI 84 8*************************************************************876 PP == domain 2 score: 59.0 bits; conditional E-value: 8.5e-20 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrdetgrskgfafVeFedeedaekAlealng.kelgg 66 lfVg +++ +te++L+++Fs+fG i+++++ rd++g+skg+af +F ++ +a++A+ ++++ ++++g FUN_001157-T1 108 LFVGMISRKATEDDLRMMFSPFGAIEELTILRDSDGKSKGCAFLKFPSRMQAQNAIGEMHNsTTMEG 174 8***********************************************************9666655 PP == domain 3 score: 62.8 bits; conditional E-value: 5.7e-21 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd.etgrskgfafVeFedeedaekAlealngkelggrelk 70 lf+ Lp++ t+ +L + F +fG + s++++ d +t+ sk f+fV +++ ++a++A++a++g ++g ++lk FUN_001157-T1 414 LFIYHLPQEFTDADLMQTFLPFGTVLSAKVFIDkATNLSKCFGFVSYDNARSAQDAIQAMHGFQIGTKRLK 484 89****************************************************************99985 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0011 5.8 2 58 .. 18 68 .. 17 97 .. 0.74 2 ! 8.7 0.0 0.00046 2.3 2 28 .. 106 132 .. 105 172 .. 0.90 3 ! 9.9 0.0 0.0002 1 4 70 .. 414 474 .. 411 495 .. 0.70 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0011 RRM_7 2 rkvfvGGlPiDiteeeltatfkafGkllvdWPrkaeskskaaeskaakGyvflvfed 58 k+f+G +P ++++l f+ +G++ + + ++++kG +fl f + FUN_001157-T1 18 IKLFIGQVPRTWEDKDLRPYFEPYGQIHELTVLRDR------LTRSHKGCAFLTFCS 68 599**********************98522222222......234556666666655 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00046 RRM_7 2 rkvfvGGlPiDiteeeltatfkafGkl 28 rk+fvG + te++l + f+ fG++ FUN_001157-T1 106 RKLFVGMISRKATEDDLRMMFSPFGAI 132 8************************87 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0002 RRM_7 4 vfvGGlPiDiteeeltatfkafGkllvdWPrkaeskskaaeskaakGyvflvfedeksvkaLldace 70 +f+ lP + t+++l++tf fG++l k ++ + + +k + f+ +++ +s ++ ++a + FUN_001157-T1 414 LFIYHLPQEFTDADLMQTFLPFGTVLS---AKVFIDKAT---NLSKCFGFVSYDNARSAQDAIQAMH 474 79999*******************974...343333333...3456777777888888877777765 PP >> RRM_YTH1 YTH1-like RRM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.0 0.00013 0.68 37 64 .. 57 84 .. 18 88 .. 0.84 2 ! 4.4 0.0 0.0095 49 40 63 .. 147 170 .. 134 175 .. 0.89 3 ! 6.3 0.0 0.0023 12 8 74 .. 417 488 .. 410 489 .. 0.71 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00013 RRM_YTH1 37 sksnCAFaNfkdeaaclaAqaklhdsrf 64 s+ CAF f + +a l+Aq+ lh+ ++ FUN_001157-T1 57 SHKGCAFLTFCSREAALNAQKDLHEKKI 84 5567********************9875 PP == domain 2 score: 4.4 bits; conditional E-value: 0.0095 RRM_YTH1 40 nCAFaNfkdeaaclaAqaklhdsr 63 CAF f + ++A ++h+s FUN_001157-T1 147 GCAFLKFPSRMQAQNAIGEMHNST 170 4*********************96 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0023 RRM_YTH1 8 GnlPpqtdlmelvehvsketkgleSlflisk....snC.AFaNfkdeaaclaAqaklhdsrfqsvrLvsRlr 74 lP++ ++l++ + + l ++i k s+C F+ + + ++ ++A +++h ++ + rL l+ FUN_001157-T1 417 YHLPQEFTDADLMQTFLPFGTVLSAKVFIDKatnlSKCfGFVSYDNARSAQDAIQAMHGFQIGTKRLKVQLK 488 5566666666666666666666666666655444478866************************99976665 PP >> RNA_bind RNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.0 0.00025 1.3 15 36 .. 24 45 .. 16 85 .. 0.82 2 ? 1.1 0.0 0.12 5.9e+02 22 36 .. 119 133 .. 101 174 .. 0.67 3 ! 9.2 0.0 0.00035 1.8 12 44 .. 415 452 .. 407 482 .. 0.61 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00025 RNA_bind 15 tFPkeWktsDilqlFspfGqvy 36 P++W +D+ F+p+Gq++ FUN_001157-T1 24 QVPRTWEDKDLRPYFEPYGQIH 45 57******************97 PP == domain 2 score: 1.1 bits; conditional E-value: 0.12 RNA_bind 22 tsDilqlFspfGqvy 36 + D+ FspfG + FUN_001157-T1 119 EDDLRMMFSPFGAIE 133 568999999999874 PP == domain 3 score: 9.2 bits; conditional E-value: 0.00035 RNA_bind 12 fyvtFPkeWktsDilqlFspfGqv.....yvsWlndts 44 f P+e+ D++q F pfG+v +++ + s FUN_001157-T1 415 FIYHLPQEFTDADLMQTFLPFGTVlsakvFIDKATNLS 452 55567*****************8622222455444444 PP >> RRM_10 RRM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.024 1.2e+02 19 89 .. 116 184 .. 108 190 .. 0.73 2 ! 10.3 0.0 0.00017 0.85 11 79 .. 414 482 .. 408 488 .. 0.87 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.024 RRM_10 19 dlteeklkevfeeagakapkkvkifpkkserss.sGlvefesveeAleaLvlaNh.tpienpsgkfpfilKLc 89 + te++l+ +f+ ga +++++i+ + +s+ + +++f s +A +a+ +++ t++e + p ++K++ FUN_001157-T1 116 KATEDDLRMMFSPFGA--IEELTILRDSDGKSKgCAFLKFPSRMQAQNAIGEMHNsTTME--GCPSPIVVKFA 184 6799999999999997..55666666665454435689************8664404444..46777777765 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00017 RRM_10 11 LhFfnappdlteeklkevfeeagakapkkvkifpkksersssGlvefesveeAleaLvlaNhtpienps 79 L+ ++ p+++t+ +l + f g+ +kv i ++++ G+v +++ ++A +a+ +++ ++i +++ FUN_001157-T1 414 LFIYHLPQEFTDADLMQTFLPFGTVLSAKVFIDKATNLSKCFGFVSYDNARSAQDAIQAMHGFQIGTKR 482 78899*****************99888888888888877889*****************9999997765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (497 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1001 (0.0391858); expected 510.9 (0.02) Passed bias filter: 658 (0.0257585); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.44s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 4840.11 // Query: FUN_001158-T1 [L=233] Description: FUN_001158 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00024 21.2 0.0 0.00034 20.7 0.0 1.2 1 MTS Methyltransferase small domain 0.0091 17.2 0.0 0.018 16.2 0.0 1.5 1 Methyltransf_25 Methyltransferase domain ------ inclusion threshold ------ 0.14 12.4 0.0 0.47 10.7 0.0 1.8 2 SH3_Hsr9 Hsr-9 Tudor domain Domain annotation for each model (and alignments): >> MTS Methyltransferase small domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 4e-08 0.00034 30 157 .. 56 183 .. 46 193 .. 0.77 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 4e-08 MTS 30 elsgkvlDlGcGaGvlglalake..speaevtlvdvnarAvesarenlkankleaevvasdvlsevedkkfdliisNP.Pfhagkatelavaqeli 122 ++ g+vl lG G+G+ ++ +++ ++++ v++ d+ + ++ e+++++ ++ ++++v+ +++d +fd i+ P+ ++ +++ + + FUN_001158-T1 56 SKGGRVLELGFGMGISATKVQSFpvKEHVIVECNDNVFKRLATFAETAAQKVTPLKGLWEEVVPALDDVSFDGILYDTyPLTEDTW-HTHQFHFIK 150 3889**********9999999862244555889999999999999999999999*********************97548888876.677788888 PP MTS 123 aeAaeaLksgGelliVanrklgyeelleevfgnve 157 ++A + L++gG l+ + ell++ f+++e FUN_001158-T1 151 NHAFRLLRPGGVLTYCNLT--SWGELLKTRFNDIE 183 99*********99865433..33345555555554 PP >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 2.2e-06 0.018 1 97 [] 61 161 .. 61 161 .. 0.83 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.2e-06 Methyltransf_25 1 vLdlGcGtGrlalelakrlgeaevtgvDlseemlerareraaeeglnvefvqgdaed.lp.fedgsfdlvvssga.lhh..lsdedleaalaei 89 vL+lG G G a ++++ + +e + v+ +++ +r+++ a+ + +v+ ++g e+ +p ++d sfd ++ + l +++++ + + +++ FUN_001158-T1 61 VLELGFGMGISATKVQSF-PVKEHVIVECNDNVFKRLATFAETAAQKVTPLKGLWEEvVPaLDDVSFDGILYDTYpLTEdtWHTHQFHFIKNHA 153 9*************9977.8999******************99888*********9955646788******95555654424445555566789 PP Methyltransf_25 90 arvLkpgG 97 +r+L+pgG FUN_001158-T1 154 FRLLRPGG 161 9******9 PP >> SH3_Hsr9 Hsr-9 Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 0.45 3.8e+03 59 76 .. 21 38 .. 5 45 .. 0.68 2 ? 10.7 0.0 5.6e-05 0.47 8 72 .. 128 192 .. 124 205 .. 0.88 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.45 SH3_Hsr9 59 kkdgdevleeveiveaPs 76 ++d de++e+ ei+ P FUN_001158-T1 21 TADYDETDEHLEILGKPV 38 348889999999988886 PP == domain 2 score: 10.7 bits; conditional E-value: 5.6e-05 SH3_Hsr9 8 reyYpakvverdglgrykvlFveDglvrklvatgiiplaalkegkkvltttkkdgdevleeveiv 72 +Y + + +d+ ++ +F++ ++ r l + g+++ ++l++ ++l t +d +++ ee+++ FUN_001158-T1 128 GILYDTYPLTEDTWHTHQFHFIKNHAFRLLRPGGVLTYCNLTSWGELLKTRFNDIEKMFEETQVP 192 5567777778899999**********************************999999999998875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (233 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 538 (0.0210609); expected 510.9 (0.02) Passed bias filter: 513 (0.0200822); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2303.46 // Query: FUN_001159-T1 [L=66] Description: FUN_001159 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.8 0.2 0.2 12.1 0.2 1.4 1 DNApolII_insertion DNA polymerase II, insertion domain Domain annotation for each model (and alignments): >> DNApolII_insertion DNA polymerase II, insertion domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.2 8e-06 0.2 19 48 .. 32 60 .. 23 63 .. 0.77 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 8e-06 DNApolII_insertion 19 gerevelrpLaLkDFhhrPvlGLYcrqyRq 48 + ++ve r+ + k++hhr +G+Y+ +yR+ FUN_001159-T1 32 KTEQVE-REAESKNYHHRKKIGIYSTRYRN 60 445555.5556799***************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (66 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 793 (0.0310433); expected 510.9 (0.02) Passed bias filter: 337 (0.0131924); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 671.04 // Query: FUN_001160-T1 [L=827] Description: FUN_001160 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-172 573.7 0.1 7.2e-172 573.4 0.1 1.0 1 Carn_acyltransf Choline/Carnitine o-acyltransferase Domain annotation for each model (and alignments): >> Carn_acyltransf Choline/Carnitine o-acyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 573.4 0.1 2.8e-176 7.2e-172 3 572 .. 211 800 .. 209 802 .. 0.91 Alignments for each domain: == domain 1 score: 573.4 bits; conditional E-value: 2.8e-176 Carn_acyltransf 3 vPsLeeTleryleslkpllseeelekteklveeflkgeGekLqerLeerakkkeetnWledwWedyaYleyrdplvvnsnpflvlekedpkkkd 96 vPsL++T++++l+s+kp+l+++e++k+e+l+++f+k++G+kLq L+ ++ + n+ +dwWe+y+Yl r+pl++nsn++++ ++ +p+ FUN_001160-T1 211 VPSLSNTCKELLNSVKPILDDKEFKKMEELAKDFEKNLGPKLQFILKLKSWWAP--NYHTDWWEKYVYLMGRSPLPINSNYYCLDQNWHPT--- 299 9*********************************************99988877..***************************87654444... PP Carn_acyltransf 97 eetqlkraAklivaalefkkkldreelep.evr.gkplcmsqykrlfnttRiPgkerDklktakeslkesrhivVlrkgqfykvdvldsdgkll 188 +q++raA +++ +l++++++++e+lep +r ++p+cm+qy+r f+ttRiP+++ D+l +++ + e++hi+V++ g++y ++v++s+gk l FUN_001160-T1 300 -LNQASRAATITYFCLKYYQEIRSETLEPlHIRkTIPICMWQYERTFKTTRIPKEDVDELVHFEPT--ENEHIIVFCGGNIYILPVTNSKGKYL 390 .47**************************88866777*********************99999997..9*******************9***** PP Carn_acyltransf 189 speelekqlqeIled.eskseeeeeeeepvGvLTtenRdeWakareellklspk.NkesleaIesalfvvcLDdeepkaksllegshgkgsqgg 280 s+ +le q++ I +d +++ +++ e++v++LT+ +R+eWa++r+e+++ + N+++leaIe+alfvv+L+d++ + l+e++ + ++ + FUN_001160-T1 391 STLDLEGQFEWIQADvKHSGAVKDQPESSVPALTALPRKEWASIRKEYFS--EGlNRQALEAIEEALFVVVLEDKSF--TDLSERA-KYVLHAD 479 ************9999555556678899********************66..455******************9977..3333333.5566666 PP Carn_acyltransf 281 gtnRWfDKslqlivtknGkaglngEHspaDgtvvlrlvey......vlksikeekss............ksssssssseae.pekLefeldeel 355 g++ WfDKs+ l+v+++Gk+g+n+EHs+aD++v+ +++ey + ++ ++s+ ++++ + p +L ++++++l FUN_001160-T1 480 GRSIWFDKSFCLMVFSDGKCGVNAEHSWADAPVLGHMLEYavtyefI------YRTYndkgkcspiggaHKSAHLRTHNLQkPARLYWDMTPKL 567 ****************************************7666642......22223344467888985566666666666************ PP Carn_acyltransf 356 keaieeaeerldklisdldlkvlefkeyGknfikkfklspDafvQmalQlAyyrlh.gklaatyEsastrkFrhGRtEtirsvteesvafvkam 448 e +e+a + +k +d++ vl ++ +Gk+fik++k+spDaf+Q+alQ+Ayyr+ g+ + tyEs++tr++ +GRtEt+rs t+e+++fv a+ FUN_001160-T1 568 TEIVENAVKFSQKNNDDTQHYVLVHDAFGKGFIKQMKVSPDAFIQLALQVAYYRDSgGRHPLTYESSMTRLYLQGRTETVRSFTMEAKEFVLAF 661 *******************************************************97899********************************** PP Carn_acyltransf 449 ldpsasdeeklellrkAvkahskltkeaskGkGvdrHLfgLklvakeeelepplfsdpaykkssnwvLsTSqlssealel.............. 528 +++++s e+k el+ kA++ h k +k++++G+G+drHLf+L++v+k ++ e +++++ s w+LsTSq ++++++ FUN_001160-T1 662 ENKAVSIETKYELFLKAANLHAKKYKDCMNGMGIDRHLFALYIVCKGQGFESEFLKSA---LSLPWTLSTSQQPQQQMSSqyfsvtepelrhqi 752 *************************************************888888887...6889**********9988889999********* PP Carn_acyltransf 529 ...fgfgpvvpdGyGiaYii.kddsikfvisskkssketsterfakaL 572 +gfgpv+++GyG++Y++ +d++i f+issk s ket+++rf k+L FUN_001160-T1 753 spgGGFGPVADNGYGVSYMVpDDNQIFFHISSKISAKETDSNRFFKHL 800 *******************956677999*****999********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (827 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1153 (0.045136); expected 510.9 (0.02) Passed bias filter: 879 (0.0344099); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 8031.53 // Query: FUN_001162-T1 [L=187] Description: FUN_001162 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-40 139.4 0.0 1.3e-40 139.2 0.0 1.1 1 DHFR_1 Dihydrofolate reductase Domain annotation for each model (and alignments): >> DHFR_1 Dihydrofolate reductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 139.2 0.0 4.9e-45 1.3e-40 2 159 .] 7 184 .. 6 184 .. 0.85 Alignments for each domain: == domain 1 score: 139.2 bits; conditional E-value: 4.9e-45 DHFR_1 2 islivAvdengvIGkdnklpwhlpeDlkrFkkltl.......gkpvimGRktfeslg...kpLpnRknivltrnkdlkvegvevvksleeal.... 83 +s++vAv++ng IGk+n+lpwhl+ D+k+F +lt ++vimGR+t+es++ +pLp+R nivl+r+++ eg+ +++sl++al FUN_001162-T1 7 FSCVVAVADNGGIGKENRLPWHLKGDMKFFSHLTStvategkQNAVIMGRNTWESIPkkyRPLPRRLNIVLSRKMSEPPEGAVLCSSLQDALdrlr 102 689****************************98742233322478***********98899***************9999************6555 PP DHFR_1 84 .alakkk.....eevfiiGGaeiykqllplad..klylteidaefegdtffPeideeewelvsreeeekd..eknkyeltfvtyer 159 a + e+vf+iGGa++y++++++ + +ly+t+i ++fe+d+ fPe+d+ ++++++ + +++ e++ ++++f +y++ FUN_001162-T1 103 sA----RytdtvEKVFVIGGATVYEEAMQHHQcyRLYMTHIYKDFECDVKFPEFDKGIYKETRDIDVSSEmlEEKGIPYEFKVYQK 184 42....133446***************9864444****************************998776553377899999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 580 (0.022705); expected 510.9 (0.02) Passed bias filter: 503 (0.0196907); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.42s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1855.73 // Query: FUN_001162-T2 [L=186] Description: FUN_001162 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-40 139.5 0.0 1.2e-40 139.2 0.0 1.1 1 DHFR_1 Dihydrofolate reductase Domain annotation for each model (and alignments): >> DHFR_1 Dihydrofolate reductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 139.2 0.0 4.8e-45 1.2e-40 2 159 .] 7 184 .. 6 184 .. 0.85 Alignments for each domain: == domain 1 score: 139.2 bits; conditional E-value: 4.8e-45 DHFR_1 2 islivAvdengvIGkdnklpwhlpeDlkrFkkltl.......gkpvimGRktfeslg...kpLpnRknivltrnkdlkvegvevvksleeal.... 83 +s++vAv++ng IGk+n+lpwhl+ D+k+F +lt ++vimGR+t+es++ +pLp+R nivl+r+++ eg+ +++sl++al FUN_001162-T2 7 FSCVVAVADNGGIGKENRLPWHLKGDMKFFSHLTStvategkQNAVIMGRNTWESIPkkyRPLPRRLNIVLSRKMSEPPEGAVLCSSLQDALdrlr 102 689****************************98742233322478***********98899***************9999************6555 PP DHFR_1 84 .alakkk.....eevfiiGGaeiykqllplad..klylteidaefegdtffPeideeewelvsreeeekd..eknkyeltfvtyer 159 a + e+vf+iGGa++y++++++ + +ly+t+i ++fe+d+ fPe+d+ ++++++ + +++ e++ ++++f +y++ FUN_001162-T2 103 sA----RytdtvEKVFVIGGATVYEEAMQHHQcyRLYMTHIYKDFECDVKFPEFDKGIYKETRDIDVSSEmlEEKGIPYEFKVYQK 184 42....133446***************9864444****************************998776553377899999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (186 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 568 (0.0222353); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1840.42 // Query: FUN_001163-T1 [L=254] Description: FUN_001163 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-38 133.3 0.3 1.4e-38 133.1 0.3 1.0 1 PEX11 Peroxisomal biogenesis factor 11 (PEX11) Domain annotation for each model (and alignments): >> PEX11 Peroxisomal biogenesis factor 11 (PEX11) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 133.1 0.3 5.4e-43 1.4e-38 4 221 .. 5 239 .. 2 240 .. 0.87 Alignments for each domain: == domain 1 score: 133.1 bits; conditional E-value: 5.4e-43 PEX11 4 lvkflaktqgrDKllRllqYasrllayylerkgsskelvkklkklesqfslsRKllRlgkflehlqaaaklld.nkledpvlrllavlrnlgyalY 98 l +l++++gr+K++R+lqYas l++ l + s ++ +k+ + + +s +R +lRl+++ +++ +a++++ ++++d+++r+++++ l+ ++ FUN_001163-T1 5 LTVVLETYRGREKIMRILQYASFLASGGLSKV-SCGSAGDKFLIFAEAMSECRTVLRLFDDAAMISYARSYGTgKEEKDKIVRWTNLVDILSGLTF 99 67789********************9988655.9999************************************77777****************** PP PEX11 99 lllDhvlwlkklgllkvknakklsrissrfwlfglllslvrdlrelrklqekekklkke.......kekeeneeek..........lkkvlkk... 174 ++l+h+ w+++ +ll+ +++ k++ s ++w ++l++ ++rdl+ l+klq++e k + l k ++k FUN_001163-T1 100 YPLEHIAWARDKKLLSGNSS-KFWDASLYCWIVSLVACIIRDLWLLKKLQQQETKRPGPktgsghsS-------FPhsnnesvspiLVKNKQKrcl 187 *****************999.99999***************************88776655555551.......3344555556774444444122 PP PEX11 175 rpaalldlvknllDllialnel..gil...klsdgvvGlaGliSSllglyql 221 ++ ++++++ +Dl +a+n+ gil kls++ vGl+G++SSl ly++ FUN_001163-T1 188 QNRLIISVIGFTADLAMAINWApqGILwaqKLSTWSVGLLGTLSSLCELYKY 239 46789999999***********9988899*****************999975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (254 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 601 (0.0235271); expected 510.9 (0.02) Passed bias filter: 521 (0.0203954); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2475.75 // Query: FUN_001164-T1 [L=94] Description: FUN_001164 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-11 43.5 0.1 6.7e-11 43.0 0.1 1.3 1 Ig_3 Immunoglobulin domain 4.9e-10 39.8 0.1 2.1e-09 37.8 0.1 1.8 1 I-set Immunoglobulin I-set domain 1.1e-08 35.6 0.2 1.3e-08 35.4 0.2 1.1 1 Ig_2 Immunoglobulin domain 4e-06 27.5 0.2 1.1e-05 26.1 0.2 1.7 1 ig Immunoglobulin domain 4.4e-06 27.3 0.6 0.081 13.6 0.2 2.1 2 V-set Immunoglobulin V-set domain 0.0061 17.4 0.2 0.0077 17.1 0.2 1.1 1 Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 ------ inclusion threshold ------ 0.037 14.5 0.4 0.058 13.8 0.4 1.4 1 Izumo-Ig Izumo-like Immunoglobulin domain 0.039 14.8 0.1 0.053 14.4 0.1 1.3 1 Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.0 0.1 2.1e-14 6.7e-11 2 78 .] 5 71 .. 4 71 .. 0.88 Alignments for each domain: == domain 1 score: 43.0 bits; conditional E-value: 2.1e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P i +p+s +v+ g +++L C+++g++ +++Wy+ +k + +++s+L+i+++ +d+G+Y+C+ sN FUN_001164-T1 5 PIIERHPESCTVQLGRDCNLFCHVTGKNL-KYRWYRRSKC-LE--------RETSSVLHIRKAAMNDAGQYSCIISN 71 889999******************77655.8*****9993.22........35779********************9 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.8 0.1 6.5e-13 2.1e-09 3 90 .] 7 84 .. 5 84 .. 0.90 Alignments for each domain: == domain 1 score: 37.8 bits; conditional E-value: 6.5e-13 I-set 3 ftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +++++++ +v+ G +++l c+v+G+ +++ +W+++ + l+ e ++ L+I+++ ++D+G+Y+c ++n +++ + a++ V FUN_001164-T1 7 IERHPESCTVQLGRDCNLFCHVTGK-NLKYRWYRRSKCLER---------ETSSVLHIRKAAMNDAGQYSCIISNDKESVITWATVDV 84 8899********************9.77******9999994.........55689*********************999988888776 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.4 0.2 4e-12 1.3e-08 2 67 .. 5 73 .. 4 85 .. 0.85 Alignments for each domain: == domain 1 score: 35.4 bits; conditional E-value: 4e-12 Ig_2 2 pvltasp..tvvtegesvtLtCsasgnppakytwykdgkvlsssqn..fftsnvsaedsGtYtCtarntk 67 p+++++p +v g + +L C++ g+ + ky+wy+ +k l+ ++ ++++++ +d+G Y+C +n+k FUN_001164-T1 5 PIIERHPesCTVQLGRDCNLFCHVTGK-NLKYRWYRRSKCLERETSsvLHIRKAAMNDAGQYSCIISNDK 73 6777666546688999**********8.**************555446888***************9987 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.2 3.5e-09 1.1e-05 4 76 .. 15 75 .. 12 80 .. 0.90 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 3.5e-09 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggs 76 tv+ G +L C+++ ++ + W + k ++++ t+s l+i+++ ++daG Y+C +n s FUN_001164-T1 15 TVQLGRDCNLFCHVT--GKNLKYRWYRRSKCLERE----------TSSVLHIRKAAMNDAGQYSCIISNDKES 75 78899999*******..**********99999988..........77********************997766 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.2 2.5e-05 0.081 3 38 .. 11 42 .. 9 48 .. 0.89 2 ! 12.7 0.0 5e-05 0.16 70 98 .. 47 75 .. 43 85 .. 0.77 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.5e-05 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqpp 38 p++ tv++G + +L C+++ ++ +++Wyr+++ FUN_001164-T1 11 PESCTVQLGRDCNLFCHVTG----KNLKYRWYRRSK 42 8999************9996....5********874 PP == domain 2 score: 12.7 bits; conditional E-value: 5e-05 V-set 70 rsdfsltiqnltlsDsGtYtCavipkgev 98 +++ l+i+++ ++D+G Y C + +++e+ FUN_001164-T1 47 ETSSVLHIRKAAMNDAGQYSCIISNDKES 75 56778****************98555444 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.2 2.4e-06 0.0077 7 62 .. 19 74 .. 15 84 .. 0.84 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 2.4e-06 Ig_5 7 gttVtltCpeese.eeikWekndkelkdkeekeLvlenFsevedsGyysCykesskk 62 g++ l C + + + +W + k l+ ++++ L + + + ++d G+ysC ++ k+ FUN_001164-T1 19 GRDCNLFCHVTGKnLKYRWYRRSKCLERETSSVLHIRK-AAMNDAGQYSCIISNDKE 74 677788898776646889******************98.99**********999655 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.4 1.8e-05 0.058 15 82 .. 22 83 .. 13 89 .. 0.71 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.8e-05 Izumo-Ig 15 CelsWHklseGltdYsFyrvwenssetllskgkestLtkpmvgledaGtYRCeLdtvksspatiihfk 82 C+l H + + l +Y++yr s+ l + s+L + +++daG+Y C + + k+s++t + + FUN_001164-T1 22 CNLFCHVTGKNL-KYRWYRR----SK-CLERETSSVLHIRKAAMNDAGQYSCIISNDKESVITWATVD 83 555555544443.4555542....22.456677889999999******************99876655 PP >> Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.1 1.7e-05 0.053 66 100 .. 45 78 .. 22 83 .. 0.77 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1.7e-05 Zwei_Ig_N 66 snekraylefgkatveeaGkYrCeittedgelvtG 100 ++e+ ++l++ ka +++aG+Y C i +e+v FUN_001164-T1 45 ERETSSVLHIRKAAMNDAGQYSCIISND-KESVIT 78 4456788****************87654.445544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (94 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 659 (0.0257976); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 952.17 // Query: FUN_001164-T2 [L=98] Description: FUN_001164 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-11 43.3 0.1 7.6e-11 42.8 0.1 1.3 1 Ig_3 Immunoglobulin domain 5.8e-10 39.6 0.1 2.4e-09 37.6 0.1 1.8 1 I-set Immunoglobulin I-set domain 1.3e-08 35.4 0.2 1.5e-08 35.2 0.2 1.1 1 Ig_2 Immunoglobulin domain 4.6e-06 27.3 0.2 1.3e-05 25.9 0.2 1.7 1 ig Immunoglobulin domain 5.2e-06 27.1 0.6 0.078 13.7 0.2 2.1 2 V-set Immunoglobulin V-set domain 0.0068 17.3 0.2 0.0087 16.9 0.2 1.2 1 Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 ------ inclusion threshold ------ 0.041 14.3 0.4 0.065 13.7 0.4 1.4 1 Izumo-Ig Izumo-like Immunoglobulin domain 0.043 14.7 0.1 0.059 14.2 0.1 1.3 1 Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.8 0.1 2.4e-14 7.6e-11 2 78 .] 9 75 .. 8 75 .. 0.88 Alignments for each domain: == domain 1 score: 42.8 bits; conditional E-value: 2.4e-14 Ig_3 2 PvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P i +p+s +v+ g +++L C+++g++ +++Wy+ +k + +++s+L+i+++ +d+G+Y+C+ sN FUN_001164-T2 9 PIIERHPESCTVQLGRDCNLFCHVTGKNL-KYRWYRRSKC-LE--------RETSSVLHIRKAAMNDAGQYSCIISN 75 889999******************77655.8*****9993.22........35779********************9 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.6 0.1 7.6e-13 2.4e-09 3 90 .] 11 88 .. 9 88 .. 0.90 Alignments for each domain: == domain 1 score: 37.6 bits; conditional E-value: 7.6e-13 I-set 3 ftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +++++++ +v+ G +++l c+v+G+ +++ +W+++ + l+ e ++ L+I+++ ++D+G+Y+c ++n +++ + a++ V FUN_001164-T2 11 IERHPESCTVQLGRDCNLFCHVTGK-NLKYRWYRRSKCLER---------ETSSVLHIRKAAMNDAGQYSCIISNDKESVITWATVDV 88 8899********************9.77******9999994.........55689*********************999988888766 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.2 0.2 4.6e-12 1.5e-08 2 67 .. 9 77 .. 8 89 .. 0.85 Alignments for each domain: == domain 1 score: 35.2 bits; conditional E-value: 4.6e-12 Ig_2 2 pvltasp..tvvtegesvtLtCsasgnppakytwykdgkvlsssqn..fftsnvsaedsGtYtCtarntk 67 p+++++p +v g + +L C++ g+ + ky+wy+ +k l+ ++ ++++++ +d+G Y+C +n+k FUN_001164-T2 9 PIIERHPesCTVQLGRDCNLFCHVTGK-NLKYRWYRRSKCLERETSsvLHIRKAAMNDAGQYSCIISNDK 77 6777666546688999**********8.**************555446888***************9987 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.2 4e-09 1.3e-05 4 76 .. 19 79 .. 16 84 .. 0.90 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 4e-09 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggs 76 tv+ G +L C+++ ++ + W + k ++++ t+s l+i+++ ++daG Y+C +n s FUN_001164-T2 19 TVQLGRDCNLFCHVT--GKNLKYRWYRRSKCLERE----------TSSVLHIRKAAMNDAGQYSCIISNDKES 79 78899999*******..**********99999988..........77********************997766 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.2 2.4e-05 0.078 3 38 .. 15 46 .. 13 55 .. 0.88 2 ! 12.5 0.0 5.4e-05 0.17 70 98 .. 51 79 .. 47 89 .. 0.77 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2.4e-05 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqpp 38 p++ tv++G + +L C+++ ++ +++Wyr+++ FUN_001164-T2 15 PESCTVQLGRDCNLFCHVTG----KNLKYRWYRRSK 46 8999************9996....5********875 PP == domain 2 score: 12.5 bits; conditional E-value: 5.4e-05 V-set 70 rsdfsltiqnltlsDsGtYtCavipkgev 98 +++ l+i+++ ++D+G Y C + +++e+ FUN_001164-T2 51 ETSSVLHIRKAAMNDAGQYSCIISNDKES 79 56778****************98555444 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.2 2.7e-06 0.0087 7 62 .. 23 78 .. 19 88 .. 0.84 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 2.7e-06 Ig_5 7 gttVtltCpeese.eeikWekndkelkdkeekeLvlenFsevedsGyysCykesskk 62 g++ l C + + + +W + k l+ ++++ L + + + ++d G+ysC ++ k+ FUN_001164-T2 23 GRDCNLFCHVTGKnLKYRWYRRSKCLERETSSVLHIRK-AAMNDAGQYSCIISNDKE 78 677788898776646889******************98.99**********999654 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.4 2e-05 0.065 29 82 .. 39 87 .. 17 93 .. 0.71 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2e-05 Izumo-Ig 29 YsFyrvwenssetllskgkestLtkpmvgledaGtYRCeLdtvksspatiihfk 82 Y++yr s+ l + s+L + +++daG+Y C + + k+s++t + + FUN_001164-T2 39 YRWYRR----SK-CLERETSSVLHIRKAAMNDAGQYSCIISNDKESVITWATVD 87 555542....22.456677889999999******************99876655 PP >> Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 1.8e-05 0.059 66 100 .. 49 82 .. 27 87 .. 0.77 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.8e-05 Zwei_Ig_N 66 snekraylefgkatveeaGkYrCeittedgelvtG 100 ++e+ ++l++ ka +++aG+Y C i +e+v FUN_001164-T2 49 ERETSSVLHIRKAAMNDAGQYSCIISND-KESVIT 82 4456788****************87654.445544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (98 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 701 (0.0274418); expected 510.9 (0.02) Passed bias filter: 508 (0.0198865); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1000.45 // Query: FUN_001165-T1 [L=827] Description: FUN_001165 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-13 50.4 0.0 0.00044 21.0 0.0 3.5 3 Ank_4 Ankyrin repeats (many copies) 7e-12 46.3 0.6 6.4e-06 27.1 0.2 2.5 2 Ank_2 Ankyrin repeats (3 copies) 1.6e-09 37.9 0.0 0.17 12.8 0.0 4.5 4 Ank Ankyrin repeat 8.5e-05 23.3 0.2 1.2 10.1 0.0 3.3 3 Ank_5 Ankyrin repeats (many copies) 0.00012 22.7 0.0 4 8.8 0.0 4.5 4 Ank_3 Ankyrin repeat 0.0037 17.3 1.3 0.047 13.7 0.2 2.5 2 Mtrc-MtrF_II-IV_dom Outer membrane cytochrome MtrC/MtrF-like ------ inclusion threshold ------ 0.18 13.4 0.8 0.6 11.6 0.8 1.9 1 DUF4168 Domain of unknown function (DUF4168) Domain annotation for each model (and alignments): >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 3e-05 0.11 1 39 [. 10 48 .. 10 54 .. 0.93 2 ! 21.0 0.0 1.2e-07 0.00044 8 50 .] 55 98 .. 50 98 .. 0.91 3 ! 16.0 0.0 4.6e-06 0.017 10 50 .] 91 131 .. 87 131 .. 0.95 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 3e-05 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAas 39 l++A ++++l+l+++L+e g + n +++ et+L +++ FUN_001165-T1 10 LFQASSACKLRLVRMLIEGGTSANVRNERLETPLMLCCQ 48 7899******************************99986 PP == domain 2 score: 21.0 bits; conditional E-value: 1.2e-07 Ank_4 8 ghlellklLlengadinatdgngetaLhfAasngn.levlklLl 50 +++++ +Ll+++a +n +d +g+taL +A++ ++ e+++ Ll FUN_001165-T1 55 EKQKVTNYLLSKKAKVNLQDIDGRTALIHASLSNSgKEIIQALL 98 6778999************************9998799999987 PP == domain 3 score: 16.0 bits; conditional E-value: 4.6e-06 Ank_4 10 lellklLlengadinatdgngetaLhfAasngnlevlklLl 50 e+++ Ll+ +a+++ +d++ +t++++++ g+le +lL+ FUN_001165-T1 91 KEIIQALLDAKASPWLQDESKNTVFDYVINAGDLETTRLLI 131 589***********************************998 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.1 5.3e-09 1.9e-05 25 90 .] 2 74 .. 1 74 [. 0.85 2 ! 27.1 0.2 1.8e-09 6.4e-06 11 83 .. 58 133 .. 51 142 .. 0.80 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 5.3e-09 Ank_2 25 qdkngetaLhlAaknghleivklLlehg..advndnngrtaLhyAaes.....ghleivklLlekgadinakd 90 ++k g aL+ A ++ +l +v+ L+e g a+v+++ +t+L+++++s +++ ++Ll+k+a++n++d FUN_001165-T1 2 NNKLGSEALFQASSACKLRLVRMLIEGGtsANVRNERLETPLMLCCQSradaeEKQKVTNYLLSKKAKVNLQD 74 467899********************8744555588899*********66555478*******99*****997 PP == domain 2 score: 27.1 bits; conditional E-value: 1.8e-09 Ank_2 11 elvklLl.egadanlqdkngetaLhlAakng.hleivklLlehgad...vndnngrtaLhyAaesghleivklLlekg 83 ++ ++Ll ++a++nlqd +g+taL++A ++ +ei+++Ll+ +a+ + d++++t y + g le+ +lL++ FUN_001165-T1 58 KVTNYLLsKKAKVNLQDIDGRTALIHASLSNsGKEIIQALLDAKASpwlQ-DESKNTVFDYVINAGDLETTRLLIN-A 133 4789999999****9999*******99886635699*****975444434.699*********99*********93.3 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.017 62 5 32 .. 9 36 .. 6 37 .. 0.77 2 ! 12.1 0.0 8e-05 0.29 3 32 .. 40 74 .. 38 75 .. 0.81 3 ! 12.8 0.0 4.6e-05 0.17 1 32 [. 76 108 .. 76 109 .. 0.85 4 ? 2.7 0.0 0.079 2.9e+02 3 24 .. 112 133 .. 110 143 .. 0.74 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.017 Ank 5 PLHlAaraghlevvklLLkhGAdvnard 32 +L A++a l +v++L++ G + n+r+ FUN_001165-T1 9 ALFQASSACKLRLVRMLIEGGTSANVRN 36 677778778889******6467888877 PP == domain 2 score: 12.1 bits; conditional E-value: 8e-05 Ank 3 nTPLHlAa.....ragh..levvklLLkhGAdvnard 32 TPL+l++ +v ++LL++ A vn++d FUN_001165-T1 40 ETPLMLCCqsradA--EekQKVTNYLLSKKAKVNLQD 74 6*******864443..0669*******779****998 PP == domain 3 score: 12.8 bits; conditional E-value: 4.6e-05 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvnard 32 dG+T+L A+ ++ e+++ LL++ A++ ++d FUN_001165-T1 76 DGRTALIHASlSNSGKEIIQALLDAKASPWLQD 108 8*********66666********7789997776 PP == domain 4 score: 2.7 bits; conditional E-value: 0.079 Ank 3 nTPLHlAaraghlevvklLLkh 24 nT + ++ag+le+ +lL+++ FUN_001165-T1 112 NTVFDYVINAGDLETTRLLINA 133 6777777799**********43 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.0 0.00033 1.2 13 53 .. 3 43 .. 1 46 [. 0.91 2 ! 8.8 0.0 0.00087 3.2 5 55 .. 67 117 .. 63 118 .. 0.85 3 ? 5.0 0.0 0.013 48 3 44 .. 99 139 .. 97 144 .. 0.76 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00033 Ank_5 13 dgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++ g ++L A+++ l++vr+L++ g ++n+++e+ +tpl FUN_001165-T1 3 NKLGSEALFQASSACKLRLVRMLIEGGTSANVRNERLETPL 43 677889999999999*************************8 PP == domain 2 score: 8.8 bits; conditional E-value: 0.00087 Ank_5 5 gpadlnrldgegytpLhvAak.ygaleivrlLlangvdlnlkdeegltpldl 55 + a +n +d +g t+L++A+ + ei++ Ll+ +++ l+de+ +t++d+ FUN_001165-T1 67 K-AKVNLQDIDGRTALIHASLsNSGKEIIQALLDAKASPWLQDESKNTVFDY 117 5.44666777777********99999*****************9999*9998 PP == domain 3 score: 5.0 bits; conditional E-value: 0.013 Ank_5 3 engpadlnrldgegytpLhvAakygaleivrlLlangvdlnl 44 +++ a++ +d+ ++t++ + +++g le rlL++ d+++ FUN_001165-T1 99 DAK-ASPWLQDESKNTVFDYVINAGDLETTRLLINACRDNMM 139 555.55556788899*******************55555555 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.014 52 3 30 .. 7 33 .. 5 34 .. 0.87 2 ? 1.9 0.0 0.21 7.5e+02 3 29 .. 40 70 .. 38 72 .. 0.70 3 ! 8.8 0.0 0.0011 4 1 25 [. 76 100 .. 76 104 .. 0.87 4 ? 0.0 0.0 0.84 3.1e+03 3 24 .. 112 133 .. 110 137 .. 0.86 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.014 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +L++A + ++l +v++L+e g + n FUN_001165-T1 7 SEALFQASSACKLRLVRMLIE-GGTSAN 33 569******************.888777 PP == domain 2 score: 1.9 bits; conditional E-value: 0.21 Ank_3 3 ntpLhlAarngrl.....eivklLleklgadi 29 +tpL+l++ + ++ +Ll + a++ FUN_001165-T1 40 ETPLMLCCQSRADaeekqKVTNYLLS-KKAKV 70 7*******998776665446666666.66655 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0011 Ank_3 1 dgntpLhlAarngrle.ivklLlekl 25 dg+t+L +A ++++ + i+++Ll+ FUN_001165-T1 76 DGRTALIHASLSNSGKeIIQALLD-A 100 79*************66******9.4 PP == domain 4 score: 0.0 bits; conditional E-value: 0.84 Ank_3 3 ntpLhlAarngrleivklLlek 24 nt + +++ g+le +lL+++ FUN_001165-T1 112 NTVFDYVINAGDLETTRLLINA 133 89999********999999984 PP >> Mtrc-MtrF_II-IV_dom Outer membrane cytochrome MtrC/MtrF-like, domains II/IV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.2 1.3e-05 0.047 109 167 .. 304 361 .. 275 367 .. 0.77 2 ? 1.7 0.1 0.064 2.3e+02 75 105 .. 561 591 .. 542 649 .. 0.72 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.3e-05 Mtrc-MtrF_II-IV_dom 109 aelaegvltsptaaaCssCHssiddaalshmkqnggvvatskaaaeaanesCatCHspg 167 ++++ +++ + C H+++ ++++ +k+n+g +at+++ ++ ++e+Ca C + + FUN_001165-T1 304 NDSPSTAYEPADHDRCEHVHEQVY-QEINSLKNNKGFIATKEEKNKYEDETCALCPAYE 361 333478889999**********64.567777999999******************7665 PP == domain 2 score: 1.7 bits; conditional E-value: 0.064 Mtrc-MtrF_II-IV_dom 75 elsypaaaenCatCHaedeeelaeaanlsrk 105 ++ + ++ nC+ H+++++ + +++ ++ FUN_001165-T1 561 TEIIELTQMNCQNTHQNTAHLKFDGNEVGQA 591 3335566788888888877655555555544 PP >> DUF4168 Domain of unknown function (DUF4168) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.8 0.00017 0.6 16 75 .. 320 375 .. 316 378 .. 0.81 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00017 DUF4168 16 epirqqaqqeikqaiedeevpkiscnqqdsleqlpaearaiaqeyceesekivekngLtv 75 e++ +q++qei ++++++ k +++ +++++e a++ y++++e i++++gLt FUN_001165-T1 320 EHVHEQVYQEI-NSLKNN---KGFIATKEEKNKYEDETCALCPAYETKQELIIRNKGLTQ 375 7889*******.566654...3444455555899************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (827 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1047 (0.0409865); expected 510.9 (0.02) Passed bias filter: 612 (0.0239577); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 7814.85 // Query: FUN_001166-T1 [L=607] Description: FUN_001166 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-81 274.0 5.1 3.4e-81 273.7 5.1 1.1 1 MFS_1_like MFS_1 like family 1.3e-21 77.4 56.3 3.6e-11 43.1 17.3 3.2 3 MFS_1 Major Facilitator Superfamily 1.2e-13 51.4 20.2 1.2e-13 51.3 14.4 2.1 2 Nuc_H_symport Nucleoside H+ symporter 2.8e-08 33.5 19.5 0.00033 20.1 1.8 3.5 3 LacY_symp LacY proton/sugar symporter ------ inclusion threshold ------ 0.019 15.1 0.5 5 7.2 0.0 3.1 3 CPP1-like Protein CHAPERONE-LIKE PROTEIN OF POR1-like 0.074 12.0 1.1 0.15 10.9 0.3 1.9 2 MFS_3 Transmembrane secretion effector 0.52 11.2 0.1 0.52 11.2 0.1 2.5 2 MacP_activator Penicillin-binding protein 2a activator MacP Domain annotation for each model (and alignments): >> MFS_1_like MFS_1 like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 273.7 5.1 9.3e-85 3.4e-81 5 371 .. 47 557 .. 43 558 .. 0.96 Alignments for each domain: == domain 1 score: 273.7 bits; conditional E-value: 9.3e-85 MFS_1_like 5 kifYFfyfaalgallPYlglyLkslglspaeigillailpltrilapniwgvlaDrlgkrkavvllalvlaavlflslllp............... 85 k+ +Ff+f a+ga+lPYlg++ k+l l+++e+gill+++p++++l +++wg++ D+ ++ k +++++++ +v++ s ++ FUN_001166-T1 47 KLSFFFFFMATGAFLPYLGVFYKQLWLTARESGILLGVRPFVKMLCSPLWGMVTDTCNRPKVILVVSIIGTTVAHFSQSVVspfdlpcypdtngtk 142 6789**********************************************************************9987744489************ PP MFS_1_like 86 ................................................................................................ 85 FUN_001166-T1 143 iaqgtgivfhgaamehstrhrdpprglqndftseakmnvsqggsnettgsvitndpgkfakmfghgkvkgflkddehgnsvvvgeftrgestenek 238 ************************************************************************************************ PP MFS_1_like 86 .....................................lektfwvlallvvlfsffwnailallevatleklgekrkdYgrirlwGsiGfavsvfll 144 ++++f++l+++v+l++++ +++ +l+++ tl l+ ++++Ygr+rl+Gs+G+++ + + FUN_001166-T1 239 prhednprlsgksqskiltknkkrknpsrkddfrvkdNKTIFITLLVIVILGELIAAPAPMLTDSGTLAILNGREHEYGRQRLFGSVGWGIGSLMS 334 ************************************99********************************************************** PP MFS_1_like 145 Gilidtlsvellpvv.......llvllaalllislllvlileekkyesklkivkeektavseaeksllkvlkqpeviifllvalllgisvgiiynF 233 G++++ + +p +++++a+ ++++l+++ +++ ++ k + ++ + lk++ + + +f++++l+lg+s+++ +F FUN_001166-T1 335 GAVVTAFNS--CPFEdsinyvtIFYVFAVAMIMDLFVAFFFPFPTAPPKHEAST------DNEFWKGLKIFYNLKNGAFIFTLLFLGFSHSLQLSF 422 **9988776..44334567779***************99999999988877774......4445788999************************** PP MFS_1_like 234 lslYLeqlgasktllGalvalgvvaeiplflvaerllrrlGhvkllilallltalrflllavlaeslwlvllielLhalsfglvwaaaieyvrkif 329 l+++L++ g ++ l ++va+ +++e+++f++a + ++++Gh +l ++l+ ++lrfll+++l +++w+vl++e+L+++++g vw a + yv FUN_001166-T1 423 LFWFLQDIGGTPILFTVIVAVNCLSEVIMFFMATYFVQKIGHDAVLYTGLACYGLRFLLYSYL-QEPWWVLPLEALQGFTYGGVWTASVAYVG--P 515 ***************************************************************.****************************9..4 PP MFS_1_like 330 pksiqatgqalysslsfGlGralGsligGllwdlksarftFl 371 ++ at q++++++++GlG a+G ++gGl++ + +ar tF+ FUN_001166-T1 516 QPGSGATIQGIIHGVYWGLGMAVGGVLGGLMIHEIGARLTFR 557 456789***********************************8 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 3.2 2.3e-08 8.4e-05 3 75 .. 48 120 .. 48 130 .. 0.93 2 ! 40.8 20.0 4.8e-14 1.8e-10 123 320 .. 316 514 .. 277 531 .. 0.82 3 ! 43.1 17.3 9.9e-15 3.6e-11 2 173 .. 406 585 .. 405 606 .. 0.84 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 2.3e-08 MFS_1 3 laaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrfGrrr.vlllglllfalg 75 l++f+++++++++ p l + ++l +++ e g+ll++ ++ l ++l+G ++d + r + +l+++++++ ++ FUN_001166-T1 48 LSFFFFFMATGAFLPYLG-VFYKQLWLTARESGILLGVRPFVKMLCSPLWGMVTDTCNRPKvILVVSIIGTTVA 120 579***************.88899*************************************9********9998 PP == domain 2 score: 40.8 bits; conditional E-value: 4.8e-14 MFS_1 123 lgllsagfglGaalGpllggllaslfg.........wravFlilailallaavlaalllprpppeskrkkpaeeapapllpawkallrdpvlwlll 209 +g ++ ++G +G+l +g+++++f+ + ++F+++a+ ++ +++a+++ + + p++++ + e +++l+ + l++ +++ FUN_001166-T1 316 YGRQRLFGSVGWGIGSLMSGAVVTAFNscpfedsinYVTIFYVFAVAMIMDLFVAFFFPFPTAPPKHEASTDNEFWKGLKI-FYNLKNGA---FIF 407 67778999***************************99999**********9886666667777777777777777888888.66666666...777 PP MFS_1 210 alllfglaffalltllplyqevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgllllsltesslwlllallllG 305 +ll++g++ ++ l++l+++ ++ g + +l +++++ +l +i++++++++++++g+ l+ +l+++ l +l++ +l + +w+l + +l G FUN_001166-T1 408 TLLFLGFSHSLQLSFLFWFLQDIGGT-PILFTVIVAVNCLSEVIMFFMATYFVQKIGHDAVLYTGLACYGLRFLLYSYLQEP---WWVLPLEALQG 499 77777779999999999997777777.5888888***********************9766666666666666655555555...99999****** PP MFS_1 306 fgfglvfplllalvs 320 f++g v++++ a+v FUN_001166-T1 500 FTYGGVWTASVAYVG 514 *********999885 PP == domain 3 score: 43.1 bits; conditional E-value: 9.9e-15 MFS_1 2 llaaflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlqG 96 +++ ++ +++ sl ++l ++ +d+g +p ++ ++++ l +++ ++a ++++++G+ vl +gl+ ++l +ll + + w++l l +lqG FUN_001166-T1 406 IFTLLFLGFSHSLQLSFLF-WFLQDIGGTPILFTVIVAVNCLSEVIMFFMATYFVQKIGHDAVLYTGLACYGLRFLLYSyL-QEPWWVLPLEALQG 499 5788999999***999999.677999************************************************4444445.88888********* PP MFS_1 97 lgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfgwravFlilailallaavlaalll.............p 173 ++ g++++a++a+++ +++ + ++ +glG+a+G +lggl+++ +g r +F + a+ +++ +v +++ FUN_001166-T1 500 FTYGGVWTASVAYVGPQPGSGATIQGI-IHGVYWGLGMAVGGVLGGLMIHEIGARLTFRLEAASSFVILV---FFIsvnnfhenrtrysM 585 ****************88776666666.77789***********************************88...55544555555444444 PP >> Nuc_H_symport Nucleoside H+ symporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.3 0.012 43 12 87 .. 51 125 .. 43 132 .. 0.79 2 ! 51.3 14.4 3.3e-17 1.2e-13 88 365 .. 277 550 .. 272 576 .. 0.81 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.012 Nuc_H_symport 12 flqyfiWGaWlvklfsylsktlfaaaeiglvysslgiaailspilvgiiaDkflsaervlavlhligavvlflaaq 87 f ++ Ga+l+ l+ + ++ +a e g+ +l l g+++D + + +l+v+ +ig+ v +++ + FUN_001166-T1 51 FFFFMATGAFLPYLGVFYKQLWLTARESGILLGVRPFVKMLCSPLWGMVTDTCNRPKVILVVS-IIGTTVAHFSQS 125 3445668********************************************998887776665.566655555444 PP == domain 2 score: 51.3 bits; conditional E-value: 3.3e-17 Nuc_H_symport 88 vtefealflvlLvfslaymPtlaltnsiafanlrDvvtdfprirvlGtvGfilasla..flllvvsladlels...rlqlliaagvsl..llavya 176 +t f +l +++++ l+ P+ lt+s + a l+ + +++r r++G vG+ + sl ++ + +e s ++++ a++ + l++++ FUN_001166-T1 277 KTIFITLLVIVILGELIAAPAPMLTDSGTLAILNGREHEYGRQRLFGSVGWGIGSLMsgAVVTAFNSCPFEDSinyVTIFYVFAVAMImdLFVAFF 372 4666667777777789999********************************999987555555666666665522235677766554423799999 PP Nuc_H_symport 177 ltLPkiPakkkakdslkkllgldafvLlknkrllvfflvslllavvlqiyfvfanafLtevakivvklasillslsqvaeilfiLtlpfflkrfGi 272 + +P P+k++a+++ + gl+ f lkn + +f l+ l ++ lq+ f+f fL+++++ + l ++++++ ++e++++++ +f+++ G FUN_001166-T1 373 FPFPTAPPKHEASTDNEFWKGLKIFYNLKNGAF-IFTLLFLGFSHSLQLSFLF--WFLQDIGGTPI-LFTVIVAVNCLSEVIMFFMATYFVQKIGH 464 99***************************9864.5555556677777888887..6*****97554.568899*********************** PP Nuc_H_symport 273 kkvlllslvaaalrfalfaygaddepvgvvlllLslivyGvaydfffitayvfvdkevpkdirasaqGlflllvnGvGallgsilsgalvemf 365 vl +l + lrf l+ y ++ ++ l L G +y + ++ +v + a+ qG++ + G+G +g++l+g +++ FUN_001166-T1 465 DAVLYTGLACYGLRFLLYSYLQEPW-WVLPLEAL----QGFTYGGVWTASVAYVGPQPG--SGATIQGIIHGVYWGLGMAVGGVLGGLMIHEI 550 *********************4443.33344444....89999999999999**98655..46999*********************888765 PP >> LacY_symp LacY proton/sugar symporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 1.8 9e-08 0.00033 12 97 .. 46 129 .. 38 133 .. 0.86 2 ! 15.6 0.4 2e-06 0.0072 132 170 .. 308 346 .. 277 378 .. 0.74 3 ! 6.8 3.5 0.00093 3.4 260 397 .. 436 573 .. 413 586 .. 0.78 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 9e-08 LacY_symp 12 falffffyffimsayfplfpvwlkevlglsktetGivfsvislfsilfqplfGlisdklGlkkellwvislllvlfapffiyvfep 97 l+fff+f+ +a+ p++ v+ k+ l l+ e Gi+ v ++ +l pl+G+++d + +++ v+s++ +a f v +p FUN_001166-T1 46 PKLSFFFFFMATGAFLPYLGVFYKQ-LWLTARESGILLGVRPFVKMLCSPLWGMVTDTCN-RPKVILVVSIIGTTVAHFSQSVVSP 129 56889999999**********9986.689****************************976.6667889999988888887777766 PP == domain 2 score: 15.6 bits; conditional E-value: 2e-06 LacY_symp 132 vsraskfeyGkarvfGclGyalcaslaGilfsidpslvf 170 + + eyG+ r+fG++G+ +++ ++G + + +s f FUN_001166-T1 308 ILNGREHEYGRQRLFGSVGWGIGSLMSGAVVTAFNSCPF 346 5556789*********************98876666555 PP == domain 3 score: 6.8 bits; conditional E-value: 0.00093 LacY_symp 260 vfGyvttagellnalimfiaplivnriGaknalliagvimsvrilgsafattalevvilkllhalevplllvgvfkyitsafdkrlsatifligfq 355 +f + +++ l + ++ f+a ++v +iG l + + +r l ++ ++++ v l l + + + y+ + ati i FUN_001166-T1 436 LFTVIVAVNCLSEVIMFFMATYFVQKIGHDAVLYTGLACYGLRFLLYSYLQEPWWVLPLEALQGFTYGGVWTASVAYVGPQPG--SGATIQGIIHG 529 567777778888888888999************9***************************9999988888888888877654..47899999999 PP LacY_symp 356 lskqlaivllstlaGklydkvGfqtaylv..lgiivlsltlisv 397 + l++ + +l G + +++G + ++ + + v+++ isv FUN_001166-T1 530 VYWGLGMAVGGVLGGLMIHEIGARLTFRLeaASSFVILVFFISV 573 99999999999999999999998888754113444455555555 PP >> CPP1-like Protein CHAPERONE-LIKE PROTEIN OF POR1-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 1.1 4.1e+03 66 112 .. 17 61 .. 3 74 .. 0.56 2 ? 7.2 0.0 0.0014 5 100 178 .. 278 351 .. 228 370 .. 0.67 3 ? 4.0 0.6 0.013 49 153 191 .. 534 572 .. 527 576 .. 0.77 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 1.1 CPP1-like 66 ppklsasplkkspawkklqrsldtPssedlliraalflvlalltlla 112 ++k ++ ++s k ld +++ ++ ++++f + ++ + FUN_001166-T1 17 SSKKCQKYEQQSI--KMSRTILDLVDKDLVVPKLSFFFFFMATGAFL 61 2222233333333..33666678888777777777777777766665 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0014 CPP1-like 100 alflvlalltllapaesvpallLalgvgasiyflnrKekklgravlltlvaLvvGlllGsllasllqsdvsltglssee 178 ++f++l+++++l + + pa +L+ + ++ ln +e + gr l++ v+ +G l+++++++ + s +++ s + FUN_001166-T1 278 TIFITLLVIVILGELIAAPAPMLTDS--GTLAILNGREHEYGRQRLFGSVGWGIGSLMSGAVVTAFNS-CPFED--SIN 351 56666666666666666666666655..678889*****99999999999999999999999988866.66662..333 PP == domain 3 score: 4.0 bits; conditional E-value: 0.013 CPP1-like 153 vGlllGsllasllqsdvsltglsseellvslvtlvllwl 191 +G+++G++l +l+++++ + ++ e+ +s+v+lv++ FUN_001166-T1 534 LGMAVGGVLGGLMIHEIGARLTFRLEAASSFVILVFFIS 572 699999999999999988998999996666666655543 PP >> MFS_3 Transmembrane secretion effector # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.25 9.3e+02 60 91 .. 91 122 .. 87 128 .. 0.79 2 ? 10.9 0.3 4.1e-05 0.15 147 188 .. 531 572 .. 430 591 .. 0.84 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.25 MFS_3 60 llsilaGvlaDildrRkillavqlllaavsvl 91 l s l G+++D +r k++l+v ++ +v+ + FUN_001166-T1 91 LCSPLWGMVTDTCNRPKVILVVSIIGTTVAHF 122 55667799999999999999999888888766 PP == domain 2 score: 10.9 bits; conditional E-value: 4.1e-05 MFS_3 147 giniaRsvGPalgGvllaavGaalafalnalsylaviaallr 188 + +vG lgG+++ +Ga l+f l+a+s +++++ + FUN_001166-T1 531 YWGLGMAVGGVLGGLMIHEIGARLTFRLEAASSFVILVFFIS 572 55677899***********************99999876554 PP >> MacP_activator Penicillin-binding protein 2a activator MacP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 1.8 0.59 2.1e+03 28 57 .. 6 35 .. 1 37 [. 0.63 2 ? 11.2 0.1 0.00014 0.52 35 84 .. 240 290 .. 219 295 .. 0.70 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.59 MacP_activator 28 eeeeekiistkeeeteeekeeksvyKSRri 57 e+e+++ +++++++ ++ e++s+ SR i FUN_001166-T1 6 EKETSNMTERSSSKKCQKYEQQSIKMSRTI 35 334444444577777777777777778876 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00014 MacP_activator 35 istkeeeteeekeeksvyKSRrien.aKrkefqskLNkiLfivilLlilLi 84 ++++ + + + ++k +K+++ n + +++f+ k Nk +fi +l++++L FUN_001166-T1 240 RHEDNPRLSGKSQSKILTKNKKRKNpSRKDDFRVKDNKTIFITLLVIVILG 290 3334444555666777789865555267789*************9999996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (607 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1029 (0.0402819); expected 510.9 (0.02) Passed bias filter: 558 (0.0218438); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.36u 0.45s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 5732.57 // Query: FUN_001167-T1 [L=286] Description: FUN_001167 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-24 85.3 0.1 6.1e-11 42.5 0.0 2.2 2 RRM_1 RNA recognition motif ------ inclusion threshold ------ 0.28 11.7 0.0 1.4 9.4 0.0 2.1 2 RRM_7 RNA recognition motif 0.79 10.4 2.0 3.6 8.2 0.1 3.0 5 PHM7_cyt Cytosolic domain of 10TM putative phosphate transpo Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.8 0.0 2.5e-14 2.2e-10 1 64 [. 15 80 .. 15 84 .. 0.93 2 ! 42.5 0.0 7.2e-15 6.1e-11 1 65 [. 207 268 .. 207 271 .. 0.97 Alignments for each domain: == domain 1 score: 40.8 bits; conditional E-value: 2.5e-14 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd..etgrskgfafVeFedeedaekAlealngkel 64 lfV++Lp dv+ +e++ lF+ f + + l + + ++ ++afV+Fe++e+ae+A++al+g + FUN_001167-T1 15 LFVSGLPIDVKPREIYLLFRGFKGYEGSLLKLTdkQGKTLSPVAFVTFENREQAEEAKAALQGVRF 80 8*********************99999888877799999***********************9766 PP == domain 2 score: 42.5 bits; conditional E-value: 7.2e-15 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrdetgrskgfafVeFedeedaekAlealngkelg 65 lfV nL +d++e++L+++F++ +++++++ ++ ++++fVe+ d a+ A++ l+gk +g FUN_001167-T1 207 LFVANLEKDCSEQQLRDVFGETPGFRRLKMLSK---GLNPVCFVEYVDVHTAAYAKQFLHGKIIG 268 8*******************************7...*************************9987 PP >> RRM_7 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.0 0.00016 1.4 2 25 .. 13 36 .. 12 66 .. 0.92 2 ? -1.0 0.0 0.3 2.6e+03 4 23 .. 207 226 .. 205 230 .. 0.85 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00016 RRM_7 2 rkvfvGGlPiDiteeeltatfkaf 25 r +fv GlPiD++ e++ f+ f FUN_001167-T1 13 RTLFVSGLPIDVKPREIYLLFRGF 36 578***************999987 PP == domain 2 score: -1.0 bits; conditional E-value: 0.3 RRM_7 4 vfvGGlPiDiteeeltatfk 23 +fv l D +e++l + f+ FUN_001167-T1 207 LFVANLEKDCSEQQLRDVFG 226 69999999999999999987 PP >> PHM7_cyt Cytosolic domain of 10TM putative phosphate transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 0.24 2e+03 2 20 .. 13 30 .. 12 45 .. 0.77 2 ? 8.2 0.1 0.00043 3.6 119 139 .. 52 72 .. 36 112 .. 0.76 3 ? -2.5 0.1 0.84 7.2e+03 129 154 .. 145 165 .. 143 176 .. 0.58 4 ? -3.7 0.0 2 1.7e+04 3 25 .. 206 227 .. 206 229 .. 0.73 5 ? -1.7 0.0 0.48 4.1e+03 122 138 .. 242 258 .. 232 268 .. 0.75 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.24 PHM7_cyt 2 rTvlvtgiPkelrseeklk 20 rT++v+g+P +++ +e + FUN_001167-T1 13 RTLFVSGLPIDVKPRE-IY 30 9********9998444.55 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00043 PHM7_cyt 119 kkplgaaFvtfesersaaava 139 k ++aFvtfe+ ++a+++ FUN_001167-T1 52 KTLSPVAFVTFENREQAEEAK 72 33479************9984 PP == domain 3 score: -2.5 bits; conditional E-value: 0.84 PHM7_cyt 129 fesersaaavaakcaaqtqqssnptl 154 f+++++aaa+a + +++pt+ FUN_001167-T1 145 FNDIMAAAATA-----HNPFNHHPTI 165 77777777775.....2233444444 PP == domain 4 score: -3.7 bits; conditional E-value: 2 PHM7_cyt 3 TvlvtgiPkelrseeklkkffee 25 T++v ++ k+++ e++l++ f e FUN_001167-T1 206 TLFVANLEKDCS-EQQLRDVFGE 227 677777777776.8889988865 PP == domain 5 score: -1.7 bits; conditional E-value: 0.48 PHM7_cyt 122 lgaaFvtfesersaaav 138 +++Fv++ + ++aa++ FUN_001167-T1 242 NPVCFVEYVDVHTAAYA 258 57999999999999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (286 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 434 (0.0169896); expected 510.9 (0.02) Passed bias filter: 414 (0.0162067); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2833.10 // Query: FUN_001168-T1 [L=501] Description: FUN_001168 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-86 289.6 163.4 3.1e-86 289.6 163.4 2.0 2 TPH Trichohyalin-plectin-homology domain ------ inclusion threshold ------ 0.24 11.8 1.9 1.5 9.2 1.9 2.5 1 PSME4_C Proteasome activator complex subunit 4-like, C- 4.5 8.1 4.8 7.7 7.4 0.2 2.7 2 Tom37 Outer mitochondrial membrane transport complex Domain annotation for each model (and alignments): >> TPH Trichohyalin-plectin-homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -9.9 53.9 3 2.6e+04 173 308 .. 19 115 .. 6 116 .. 0.50 2 ! 289.6 163.4 3.7e-90 3.1e-86 1 352 [] 114 465 .. 114 465 .. 1.00 Alignments for each domain: == domain 1 score: -9.9 bits; conditional E-value: 3 TPH 173 aereekkeekereiarLraqqekaqdekaerdelraklaqeeaerkerqkereeaekkarqrqelkq..areeqieekerrkaeeaereeeeferv 266 ae ++k+ +re++ k+++q++ l++ a ee ie+k+ +++ +e+ e+e +++ FUN_001168-T1 19 AENRRKE------------------------------------------IAREDQLKRINQEKTLQAnmASEERIEDKRFLRRRRQEESEREMDEA 72 2333333..........................................33455555555555555555666666666666666444444444455 PP TPH 267 lekqaedeekeqeeaek.rrekrlehrrelekqieereeqrea 308 ++kq e++e +q+++e+ +r ++ + lek+ ee+ +q ++ FUN_001168-T1 73 IRKQHEQKELQQRQQEQeQRLAKELEHLKLEKMREEKLRQQIR 115 5555555555555544434444444455666666666555544 PP == domain 2 score: 289.6 bits; conditional E-value: 3.7e-90 TPH 1 lreqseelkelnskllaakcnkerdaQieekkrikeeekeeerrldemmeeerekalkeeeekeeerkeerkegrqeLeeQieereqkrqeeaeek 96 +re+s el+el++kl+ ++n+er+aQ++ek +i ++ er++++ meee ++al+ e+eke++r+ee +++++Le+Q+ e+e+ +qe++ee+ FUN_001168-T1 114 IRENSVELRELEAKLKSGYMNRERAAQLAEKMAIAMDSQAAERQIHARMEEEYKRALEVEKEKEMQRWEESVRYQEQLEKQLAEKERLKQEAYEEF 209 69********************************************************************************************** PP TPH 97 leEreqmdeivekiqeedeaeaeekkekqkklreeidefneeqkelkelekeeekeeeekileylkekaereeereaereekkeekereiarLraq 192 l+E+ ++deiv+ki+eed++e e++++kqk+++++i+ef++ ++e+k+ e++ ++ee+e+ile++k++++ree+r++++++++e ++++++L++q FUN_001168-T1 210 LKEKLMIDEIVRKIYEEDQRELENRLQKQKATQRYIEEFKTKREEWKQHERQLMEEENERILEFAKQQQKREEDRMEKKKQQEESMAAVQQKLSKQ 305 ************************************************************************************************ PP TPH 193 qekaqdekaerdelraklaqeeaerkerqkereeaekkarqrqelkqareeqieekerrkaeeaereeeefervlekqaedeekeqeeaekrrekr 288 +e++ + ++e++++r +l++ee+e+ erqke+++ e+k+rqr +l+ +r++q+e+ke+++++e+e+eee+++++l+k+aed+++eq++a+krr+k+ FUN_001168-T1 306 IEEESEAREEMERIRTELYLEEQEELERQKEKMAIENKIRQRLDLQSTRRQQLEFKEQKRQAEREEEEEFRRKMLQKFAEDDRIEQMNAQKRRMKQ 401 ************************************************************************************************ PP TPH 289 lehrrelekqieereeqreaereeeleegeklreeeaerrerieeerqkkLkehlrellgglpe 352 leh++++ek+ie+r+ q+++ere+ele +++++++e+++r++ie+erq++L+eh+++llg+lp+ FUN_001168-T1 402 LEHKKAVEKLIEDRRLQFQREREAELEARREQERMEEYKRQIIEQERQRLLREHASKLLGFLPK 465 ***************************************************************7 PP >> PSME4_C Proteasome activator complex subunit 4-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 1.9 0.00018 1.5 45 81 .. 238 273 .. 216 278 .. 0.82 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00018 PSME4_C 45 kktvkktlseFkrthqDtWeedkkkFtedqledledv 81 +k+ ++ ++eFk t++++W+++++++ e++ e + ++ FUN_001168-T1 238 QKATQRYIEEFK-TKREEWKQHERQLMEEENERILEF 273 677889999*96.6779************99988665 PP >> Tom37 Outer mitochondrial membrane transport complex protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.2 0.00091 7.7 41 84 .. 177 214 .. 168 216 .. 0.75 2 ? 1.2 0.8 0.073 6.3e+02 44 77 .. 266 298 .. 256 308 .. 0.63 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.00091 Tom37 41 wvsgfesIveylkkkseksdldaslsakqkadatalislleskl 84 +++ +e+ v+y ++ +++l +k++++++a+ ++l++kl FUN_001168-T1 177 EMQRWEESVRYQEQL------EKQLAEKERLKQEAYEEFLKEKL 214 555555666666654......569******************98 PP == domain 2 score: 1.2 bits; conditional E-value: 0.073 Tom37 44 gfesIveylkkkseksdldaslsakqkadatali 77 + e+I+e+ k++ +k++ d+ ++kq+ +++a + FUN_001168-T1 266 ENERILEFAKQQ-QKREEDRMEKKKQQEESMAAV 298 5689******99.555456555555555555443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (501 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 6292 (0.24631); expected 510.9 (0.02) Passed bias filter: 893 (0.0349579); expected 510.9 (0.02) Passed Vit filter: 400 (0.0156586); expected 25.5 (0.001) Passed Fwd filter: 101 (0.00395381); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 1.12u 0.49s 00:00:01.61 Elapsed: 00:00:00.48 # Mc/sec: 4204.51 // Query: FUN_001170-T1 [L=272] Description: FUN_001170 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-12 45.1 4.9 9.6e-12 45.1 4.9 2.3 2 SapA Saposin A-type domain 2.8e-08 34.1 10.0 1.4e-06 28.6 0.2 3.2 3 SapB_1 Saposin-like type B, region 1 2.5e-06 28.0 6.0 0.0051 17.4 0.5 3.8 3 SapB_2 Saposin-like type B, region 2 Domain annotation for each model (and alignments): >> SapA Saposin A-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.1 4.9 1.1e-15 9.6e-12 4 32 .. 27 55 .. 24 56 .. 0.96 2 ? -1.8 0.6 0.54 4.6e+03 20 27 .. 265 272 .] 264 272 .] 0.86 Alignments for each domain: == domain 1 score: 45.1 bits; conditional E-value: 1.1e-15 SapA 4 CtwGpsyWCqdletAkeCgAvkHCqqkvW 32 C++Gp+yWC+ +e A+eC+A++HC +++W FUN_001170-T1 27 CSQGPAYWCETFEKAVECNALEHCFNNAW 55 ***************************** PP == domain 2 score: -1.8 bits; conditional E-value: 0.54 SapA 20 eCgAvkHC 27 C+A++ C FUN_001170-T1 265 TCHALEMC 272 6****999 PP >> SapB_1 Saposin-like type B, region 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.3 4.1e-05 0.35 1 22 [. 70 91 .. 70 91 .. 0.95 2 ! 28.6 0.2 1.7e-10 1.4e-06 2 35 .. 196 229 .. 195 232 .. 0.94 3 ? -2.4 0.6 0.84 7.1e+03 4 14 .. 238 248 .. 238 251 .. 0.74 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 4.1e-05 SapB_1 1 plCdlCefvVkeveklLkdnkT 22 ++Cd+C+ V+ +++++ dn T FUN_001170-T1 70 DMCDFCTSSVTTLQTFVPDNVT 91 68******************88 PP == domain 2 score: 28.6 bits; conditional E-value: 1.7e-10 SapB_1 2 lCdlCefvVkeveklLkdnkTeeeIieaLekvCs 35 +C++C+f+ + k+L++ +Te++I + +C FUN_001170-T1 196 FCSVCQFMARLILKMLENEETEDTIARKISSICG 229 7********************************7 PP == domain 3 score: -2.4 bits; conditional E-value: 0.84 SapB_1 4 dlCefvVkeve 14 ++C ++V + FUN_001170-T1 238 EMCVEIVDVLV 248 58999998765 PP >> SapB_2 Saposin-like type B, region 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.2 0.00013 1.1 2 34 .] 114 148 .. 114 148 .. 0.90 2 ? 0.7 0.0 0.11 9.1e+02 13 23 .. 206 216 .. 204 218 .. 0.85 3 ! 17.4 0.5 6e-07 0.0051 2 34 .] 239 272 .] 238 272 .] 0.98 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00013 SapB_2 2 eCkslVdqYgplIidlLengld..PkdvCtalglC 34 +C +lVd+ + ++++ L + l+ +++vC +++lC FUN_001170-T1 114 KCRKLVDKVLEILWNRLDKTLSgpAEKVCIKIKLC 148 59999999999999999999777699********* PP == domain 2 score: 0.7 bits; conditional E-value: 0.11 SapB_2 13 lIidlLengld 23 lI+++Len+++ FUN_001170-T1 206 LILKMLENEET 216 79******964 PP == domain 3 score: 17.4 bits; conditional E-value: 6e-07 SapB_2 2 eCkslVdqYgplIidlLengld.PkdvCtalglC 34 +C+++Vd + ++i+ L g++ P + C+al +C FUN_001170-T1 239 MCVEIVDVLVKTVIEDLARGISnPLETCHALEMC 272 8********************************* PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 784 (0.0306909); expected 510.9 (0.02) Passed bias filter: 571 (0.0223527); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2660.67 // Query: FUN_001171-T1 [L=928] Description: FUN_001171 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-34 116.8 17.4 4.3e-17 62.6 4.9 2.6 2 WSC WSC domain 8.7e-05 22.7 0.3 0.00037 20.7 0.3 2.1 1 Tudor_2 Jumonji domain-containing protein 2A Tudor d ------ inclusion threshold ------ 0.29 11.4 4.4 0.7 10.2 1.0 2.6 2 zf-C2H2_STOP2_C STOP2-like, C2H2-type zinc finger Domain annotation for each model (and alignments): >> WSC WSC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.6 4.9 5.1e-21 4.3e-17 1 82 [] 122 199 .. 122 199 .. 0.96 2 ! 59.5 4.6 4.7e-20 4e-16 1 82 [] 327 404 .. 327 404 .. 0.96 Alignments for each domain: == domain 1 score: 62.6 bits; conditional E-value: 5.1e-21 WSC 1 ylGCysdssessrlllassasssdmtvekCvaaCkekgykyagleygkeCyCgnslpssskkaeeseCntsCsGdsselCGg 82 ylGC++d+ + l+ ++ t+++Cv++Ck++g+++ +l++++ C+Cgns+++s++ +e++ C+++C +s+e+CGg FUN_001171-T1 122 YLGCFRDN---IPRDLQVYIPTRPATIGACVDTCKSQGFSIGALRNSDLCFCGNSYSKSNQVEEKA-CDMPCYDNSYEVCGG 199 9*****99...788889999**************************************99999887.**************8 PP == domain 2 score: 59.5 bits; conditional E-value: 4.7e-20 WSC 1 ylGCysdssessrlllassasssdmtvekCvaaCkekgykyagleygkeCyCgnslpssskkaeeseCntsCsGdsselCGg 82 ++GC++ds +++ l+++ + + +tve Cv +C g+++ag+++++ C+Cg++++++ +e+ Cn++C+G+ +e+CGg FUN_001171-T1 327 FMGCFQDS---AARDLPTEIDVRPLTVEGCVFKCGRLGFSMAGVQSSSLCFCGTTYSRYGRLRNEQ-CNMRCTGNYKEICGG 404 68****99...78888999******************************************99887.**************8 PP >> Tudor_2 Jumonji domain-containing protein 2A Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.3 4.3e-08 0.00037 3 22 .. 9 28 .. 8 32 .. 0.91 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 4.3e-08 Tudor_2 3 dVivrwtDGryYlakfigih 22 +Vi rw++G+yY++++ +i+ FUN_001171-T1 9 RVISRWKNGNYYKGEIDSIT 28 7***************9997 PP >> zf-C2H2_STOP2_C STOP2-like, C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.1 0.052 4.4e+02 3 13 .. 167 177 .. 166 180 .. 0.87 2 ? 10.2 1.0 8.2e-05 0.7 3 15 .. 372 384 .. 371 386 .. 0.86 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.052 zf-C2H2_STOP2_C 3 LCsCGttFsRK 13 LC CG +s+ FUN_001171-T1 167 LCFCGNSYSKS 177 9*******975 PP == domain 2 score: 10.2 bits; conditional E-value: 8.2e-05 zf-C2H2_STOP2_C 3 LCsCGttFsRKDK 15 LC CGtt+sR + FUN_001171-T1 372 LCFCGTTYSRYGR 384 9*********765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (928 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1667 (0.0652574); expected 510.9 (0.02) Passed bias filter: 540 (0.0211392); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 8913.08 // Query: FUN_001172-T1 [L=525] Description: FUN_001172 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-44 149.8 0.3 1.9e-43 148.7 0.3 1.5 1 PRMT_C Arginine methyltransferase oligomerization s 3.5e-19 68.9 0.0 9.2e-19 67.5 0.0 1.8 1 ANM3_C2H2_Zf Protein arginine N-methyltransferase 3, C2H2 4.8e-13 50.1 0.0 1.2e-12 48.8 0.0 1.7 1 Methyltransf_25 Methyltransferase domain 3.7e-11 44.0 0.0 9e-11 42.8 0.0 1.7 1 Methyltransf_11 Methyltransferase domain 3e-10 40.5 0.0 9.3e-10 38.9 0.0 1.7 1 Methyltransf_31 Methyltransferase domain 4.9e-09 36.6 0.2 8.7e-09 35.8 0.2 1.3 1 PrmA Ribosomal protein L11 methyltransferase (Prm 8.4e-07 28.7 0.0 1.4e-06 28.0 0.0 1.2 1 Methyltransf_9 Protein of unknown function (DUF1698) 7.6e-06 26.1 0.1 1.4e-05 25.3 0.1 1.4 1 MTS Methyltransferase small domain 1.7e-05 26.0 0.0 5.5e-05 24.3 0.0 2.0 1 Methyltransf_12 Methyltransferase domain 4.9e-05 23.6 0.0 0.00011 22.5 0.0 1.6 1 Methyltransf_23 Methyltransferase domain 0.00036 21.0 0.0 0.00081 19.9 0.0 1.6 1 FtsJ FtsJ-like methyltransferase 0.0044 17.0 0.0 0.0086 16.0 0.0 1.4 1 TehB Tellurite resistance protein TehB 0.0065 16.3 0.1 0.011 15.6 0.1 1.2 1 Ubie_methyltran ubiE/COQ5 methyltransferase family 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 CMAS Mycolic acid cyclopropane synthetase ------ inclusion threshold ------ 0.014 15.6 0.1 0.03 14.6 0.1 1.4 1 PCMT Protein-L-isoaspartate(D-aspartate) O-methyl 0.016 15.7 0.1 0.03 14.8 0.1 1.3 1 Methyltransf_18 Methyltransferase domain 0.023 15.1 0.4 0.05 14.0 0.4 1.5 1 ANM3_zf-C2H2 Protein arginine N-methyltransferase 3, C2H2 0.026 15.0 0.1 0.046 14.2 0.1 1.3 1 PRMT5_C PRMT5 oligomerisation domain 0.046 14.1 0.0 0.089 13.1 0.0 1.4 1 PRMT5 PRMT5 arginine-N-methyltransferase 0.084 13.3 0.0 0.22 12.0 0.0 1.7 1 Methyltransf_32 Methyltransferase domain 0.085 12.8 0.1 0.53 10.2 0.1 2.1 2 Methyltransf_4 Putative methyltransferase 0.092 13.4 0.1 0.23 12.1 0.1 1.6 1 DUF7248 Family of unknown function (DUF7248) 0.1 12.8 0.0 0.29 11.3 0.0 1.7 1 Cons_hypoth95 Conserved hypothetical protein 95 0.13 13.0 0.4 0.13 13.0 0.4 2.3 2 zf-C2H2_2 C2H2 type zinc-finger (2 copies) 9.1 7.8 7.2 14 7.2 3.7 2.9 2 zf-C2H2_4 C2H2-type zinc finger Domain annotation for each model (and alignments): >> PRMT_C Arginine methyltransferase oligomerization subdomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 148.7 0.3 1.9e-46 1.9e-43 4 159 .. 351 507 .. 348 512 .. 0.94 Alignments for each domain: == domain 1 score: 148.7 bits; conditional E-value: 1.9e-46 PRMT_C 4 tlyvaaiedkdy.eeklkfWdnvygfdmsslkklalkeplvdevdgeavlsepasvleldlatvkkedleefsvefslevkrsdkihgvvawfdie 98 ++++aa ++ ++kl+fWdnvygf+ms++k + ep ++ v+ ++ +s+ ++v++ld+ +++ +dl +f+++f ++++++++++++va+fdi FUN_001172-T1 351 KICFAALGNSERvQRKLGFWDNVYGFKMSCMKTSVCTEPSIEIVNHKDEISSRCTVKNLDITSCQQSDL-QFKSPFTVTINADGQCSAFVAFFDIF 445 56666666555559*******************************************************.************************** PP PRMT_C 99 fske.hkkivlstaPekkytHWkQtvfylkeeleveegeeisgtvslkpnaknprdldvsle 159 f+k+ +k+ +st+P+++ tHWkQtvfyl ++++v +g+ ++g v ++++ k pr ld+++e FUN_001172-T1 446 FDKNcVQKVEFSTSPSHNPTHWKQTVFYLAHPINVTQGQILEGFVLCTKSIKDPRSLDITIE 507 *997799*****************************************************97 PP >> ANM3_C2H2_Zf Protein arginine N-methyltransferase 3, C2H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.5 0.0 9e-22 9.2e-19 1 46 [] 61 106 .. 61 106 .. 0.97 Alignments for each domain: == domain 1 score: 67.5 bits; conditional E-value: 9e-22 ANM3_C2H2_Zf 1 lvrkhsLDfYgyIKLINfIRskkpsaeslsslssplpWesdeYLkP 46 ++r+h+LDfYg+IKLINfIR++kps+esl+ + p pWes+e+L P FUN_001172-T1 61 IKRNHGLDFYGCIKLINFIRKMKPSPESLTIVAPPFPWESEEFLNP 106 5799*************************9999***********99 PP >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.8 0.0 1.2e-15 1.2e-12 1 97 [] 246 343 .. 246 343 .. 0.91 Alignments for each domain: == domain 1 score: 48.8 bits; conditional E-value: 1.2e-15 Methyltransf_25 1 vLdlGcGtGrlalelakrlgeaevtgvDlseemlerareraaeegl..nvefvqgdaedlpfedgsfdlvvssga.lhhlsdedleaalaeiar 91 vLd+GcGtG l++ +ak+ g+ +v+g+D s+ + +a + ++e+gl v++v+g++e++ ++ +++d+++s + +l ++ l+++l r FUN_001172-T1 246 VLDVGCGTGILSMFAAKA-GARHVIGIDQSD-IIYQAMDIVKENGLesVVTLVKGKVENVTLPVNKVDVIISEWMgYFLLFESMLDTVLLARDR 337 9***************99.68*******886.56778899999999999***********************777777777899********** PP Methyltransf_25 92 vLkpgG 97 +LkpgG FUN_001172-T1 338 WLKPGG 343 *****9 PP >> Methyltransf_11 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.8 0.0 8.8e-14 9e-11 1 93 [. 247 345 .. 247 346 .. 0.89 Alignments for each domain: == domain 1 score: 42.8 bits; conditional E-value: 8.8e-14 Methyltransf_11 1 LdvGcGtGllaealarlg.arvtgvDlspemlelakekakkegl...vefvqadaedlpfpdesfDlvlssevlhhv...edpekalreiaRvL 87 LdvGcGtG+l+ +a++g +v+g+D s+ +a + +k++gl v++v++ +e++ +p +++D+++s ++ ++ ++++l R+L FUN_001172-T1 247 LDVGCGTGILSMFAAKAGaRHVIGIDQSDIIY-QAMDIVKENGLesvVTLVKGKVENVTLPVNKVDVIISEWMGYFLlfeSMLDTVLLARDRWL 339 8*************************998765.55455555566677999**********************9888888899************ PP Methyltransf_11 88 kpgGll 93 kpgG + FUN_001172-T1 340 KPGGCV 345 ****76 PP >> Methyltransf_31 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.9 0.0 9.1e-13 9.3e-10 3 108 .. 242 346 .. 240 367 .. 0.77 Alignments for each domain: == domain 1 score: 38.9 bits; conditional E-value: 9.1e-13 Methyltransf_31 3 kglkvLDlGCGtGrlsfelaeelgpnaevvGiDiseeaiekArenaeklglk.nvkFeqgdieelpesledekfDviisn...evlnavpdpdk 92 k+++vLD+GCGtG ls+ +a + g +v+GiD s + i +A + +++gl+ v++ +g +e+ + l +k+Dviis + l d FUN_001172-T1 242 KDKVVLDVGCGTGILSMFAA-KAGA-RHVIGIDQS-DIIYQAMDIVKENGLEsVVTLVKGKVENVT--LPVNKVDVIISEwmgYFLLFESMLDT 330 7899****************.7665.89*****98.578888888899999999**********99..8899******9744322233333444 PP Methyltransf_31 93 vleeiervlkpggill 108 vl r lkpgg ++ FUN_001172-T1 331 VLLARDRWLKPGGCVY 346 4445557777777665 PP >> PrmA Ribosomal protein L11 methyltransferase (PrmA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.8 0.2 8.5e-12 8.7e-09 161 232 .. 242 315 .. 234 332 .. 0.76 Alignments for each domain: == domain 1 score: 35.8 bits; conditional E-value: 8.5e-12 PrmA 161 egesvlDvGtGSGiLaiaalklgakkvvgvDiDevAvkaakeNaelNkveeqlevyl.seellk..eekadvvva 232 +++ vlDvG+G+GiL++ a+k ga++v+g+D ++ + a + ++ N++e+ +++ + e ++ +k+dv+++ FUN_001172-T1 242 KDKVVLDVGCGTGILSMFAAKAGARHVIGIDQSDI-IYQAMDIVKENGLESVVTLVKgKVENVTlpVNKVDVIIS 315 67889**************************9987.555667777777777554421111222134589999997 PP >> Methyltransf_9 Protein of unknown function (DUF1698) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.0 0.0 1.3e-09 1.4e-06 113 213 .. 240 342 .. 214 349 .. 0.85 Alignments for each domain: == domain 1 score: 28.0 bits; conditional E-value: 1.3e-09 Methyltransf_9 113 dlkgrtildvGcgnGyhlwrmvgegaklvvGidPselfliqfeavrkllgedkraillplgieqlpe.leafdtvfs..mGvlyhrrsPldhllq 204 +k++++ldvGcg+G + + +ga+ v+Gid s + + ++ v++ g + ++l+ +e++ ++ d++ s mG + +s ld++l FUN_001172-T1 240 IFKDKVVLDVGCGTGILSMFAAKAGARHVIGIDQSDIIYQAMDIVKE-NGLESVVTLVKGKVENVTLpVNKVDVIISewMGYFLLFESMLDTVLL 333 579************999999999************99999988876.6899999999999***9988*******98779999999999999998 PP Methyltransf_9 205 lkdqlvkgG 213 +d k G FUN_001172-T1 334 ARDRWLKPG 342 888755544 PP >> MTS Methyltransferase small domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.1 1.3e-08 1.4e-05 31 103 .. 242 315 .. 227 316 .. 0.86 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.3e-08 MTS 31 lsgkvlDlGcGaGvlglalakespeae..vtlvdvnarAvesarenlkankle.aevvasdvlsevedkkfdliis 103 +++ vlD+GcG+G+l++ +ak+ ++ ++ +d+ ++A+++++en ++ + ++ ++v+ v+ k+d+iis FUN_001172-T1 242 KDKVVLDVGCGTGILSMFAAKAGARHVigIDQSDIIYQAMDIVKENGLESVVTlVKGKVENVTLPVN--KVDVIIS 315 56889**************999887654688899999*********999999989999999999998..9999997 PP >> Methyltransf_12 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.0 5.4e-08 5.5e-05 1 97 [. 247 344 .. 247 345 .. 0.81 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 5.4e-08 Methyltransf_12 1 LeiGcGtGallrallealpgleyvgvDispaaleaarerlaalerldaarveleqldlaeeepe..sfDvvvasnvlhhl...adleevlrnlr 89 L++GcGtG l+ ++++a +++g+D s+ +a +++++ ++ v+l + +++ + ++Dv+++ +l l+ vl FUN_001172-T1 247 LDVGCGTGILSMFAAKA-GARHVIGIDQSDIIY-QAMDIVKENGLES--VVTLVKGKVENVTLPvnKVDVIISEWMGYFLlfeSMLDTVLLARD 336 8*******999999999.777888******999.9999999999866..66777777667667778*****96533333344689999999999 PP Methyltransf_12 90 rlLkpgGv 97 r+LkpgG+ FUN_001172-T1 337 RWLKPGGC 344 *******7 PP >> Methyltransf_23 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 1e-07 0.00011 5 55 .. 226 276 .. 223 346 .. 0.75 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 1e-07 Methyltransf_23 5 rrreladlllrllpklkspgrvLDiGcGtGiflellreegf.kvvgvDpspe 55 r + ++d++l ++++ vLD+GcGtGi++ +++ g+ +v+g+D s++ FUN_001172-T1 226 RTESYRDFVLNNP-MIFKDKVVLDVGCGTGILSMFAAKAGArHVIGIDQSDI 276 5677788888774.599************************99*****9975 PP >> FtsJ FtsJ-like methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 7.9e-07 0.00081 20 61 .. 241 283 .. 231 355 .. 0.75 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 7.9e-07 FtsJ 20 kkgkvvlDlGaapGgfsqvllervgagkvvavDlgpgql..ekp 61 k+kvvlD+G+++G s ++++ ga++v+++D + + + FUN_001172-T1 241 FKDKVVLDVGCGTGILSMFAAKA-GARHVIGIDQSDIIYqaMDI 283 4899*******************.*********98773333333 PP >> TehB Tellurite resistance protein TehB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 8.4e-06 0.0086 7 128 .. 219 343 .. 215 346 .. 0.72 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 8.4e-06 TehB 7 dyfskkynltathsevveavkivkpgkvldlgcgqgrnslylsllgy.dvtawdknensiafleeikekenlknistaly.dineakld.erydfi 99 + ++k + + v++ i k vld+gcg g s++ + g +v +d+ + i +i + + l+++ t + ++++++l ++ d i FUN_001172-T1 219 EMLKDKTRTESYRDFVLNNPMIFKDKVVLDVGCGTGILSMFAAKAGArHVIGIDQSDI-IYQAMDIVKENGLESVVTLVKgKVENVTLPvNKVDVI 313 556666666666677889999999999****************999636888988765.5566667777788888887653789999863678999 PP TehB 100 lstvvlmfleae.ripsiienmqectkvgg 128 +s + fl e ++ +++ ++ k+gg FUN_001172-T1 314 ISEWMGYFLLFEsMLDTVLLARDRWLKPGG 343 999877776544144555555556666665 PP >> Ubie_methyltran ubiE/COQ5 methyltransferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.1 1.1e-05 0.011 35 150 .. 230 346 .. 221 351 .. 0.82 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.1e-05 Ubie_methyltran 35 WkkfveklvavkrgakvlDvagGtgDltfklsdsvgekgkvvvlDinenmLkvgekklkeegks.nieflqanaeeLpfeddsfDvvt...isf 124 +++fv + + + vlDv +Gtg l++ ++ ++g++ +v+++D ++ ++ + + +ke+g + +++++ e++ + + Dv+ +++ FUN_001172-T1 230 YRDFVLNNPMIFKDKVVLDVGCGTGILSM-FAAKAGAR-HVIGIDQSD-IIYQAMDIVKENGLEsVVTLVKGKVENVTLPVNKVDVIIsewMGY 320 7788888888888899*********8876.55666665.688889765.5667888899999885789999**999999999999885444899 PP Ubie_methyltran 125 GlrnvtDklkaLkeifrvlkpGGrlv 150 l + +++L r lkpGG ++ FUN_001172-T1 321 FLLFESMLDTVLLARDRWLKPGGCVY 346 99999999***************986 PP >> CMAS Mycolic acid cyclopropane synthetase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 1.2e-05 0.012 64 132 .. 244 311 .. 218 346 .. 0.84 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.2e-05 CMAS 64 mtlLdiGcGWGslvrraverydvkvvglTlSkeqaklakkrvdeldlerkvevklldyedldekfdrvv 132 + +Ld+GcG G l + a++ +v+g+ S+ + +a + v+e +le v++ + e++ ++++v FUN_001172-T1 244 KVVLDVGCGTGILSMFAAKAGARHVIGIDQSDIIY-QAMDIVKENGLESVVTLVKGKVENVTLPVNKVD 311 679*****************8889*****998766.5678999****9999999999999998777763 PP >> PCMT Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.1 3e-05 0.03 73 129 .. 242 295 .. 226 301 .. 0.80 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3e-05 PCMT 73 kgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakknlkkldlenvivv 129 k + vL+vG+G+G+l+ a+ g++ v++i+++ +++ +a +k+++le+v + FUN_001172-T1 242 KDKVVLDVGCGTGILSMFAAK-AGARH-VIGIDQS-DIIYQAMDIVKENGLESVVTL 295 55679*********9865555.56555.8****86.5777899999*9999988754 PP >> Methyltransf_18 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.1 2.9e-05 0.03 11 92 .. 239 319 .. 236 332 .. 0.86 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.9e-05 Methyltransf_18 11 lvpkgetvaDiGtDHaylpiylvkegkvkkaiavdvnkgplekakknvkkagledkievrlgdGlevlkege.vdviviaGmG 92 ++ k+++v+D+G+ ++l+++++k+g ++++i +d + + + +a + vk++gle+ +++ g+ +v + + vdvi+ mG FUN_001172-T1 239 MIFKDKVVLDVGCGTGILSMFAAKAG-ARHVIGIDQS-DIIYQAMDIVKENGLESVVTLVKGKVENVTLPVNkVDVIISEWMG 319 677899**************999887.599*****76.5677899*********************9998766**99987777 PP >> ANM3_zf-C2H2 Protein arginine N-methyltransferase 3, C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.4 4.9e-05 0.05 2 16 .. 33 47 .. 33 49 .. 0.91 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 4.9e-05 ANM3_zf-C2H2 2 CLFCdRLFsSAEDtF 16 CLFCd F AED+ FUN_001172-T1 33 CLFCDKCFKNAEDVW 47 *************96 PP >> PRMT5_C PRMT5 oligomerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 4.5e-05 0.046 63 129 .. 420 487 .. 383 496 .. 0.79 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 4.5e-05 PRMT5_C 63 erykklefkikakavlhGlagYFeakLYk....dvelSiePetktknliSWfpiffPlkkpllvkkdqele 129 + ++ + +i+a++ + +++++F+ + k +ve+S+ P++ n + W +f l +p++v+++q le FUN_001172-T1 420 QFKSPFTVTINADGQCSAFVAFFDIFFDKncvqKVEFSTSPSH---NPTHWKQTVFYLAHPINVTQGQILE 487 4444556667999999999998876554422227*******76...999*****************99776 PP >> PRMT5 PRMT5 arginine-N-methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 8.7e-05 0.089 34 146 .. 202 321 .. 195 332 .. 0.79 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 8.7e-05 PRMT5 34 EkdkvKYelYekA.iekalldlkkekkkks..........kelvilvvGaGRGplvdralkaaeelktkvkivavEKnpnavvtLqkrnkekWeek 118 E+d ++ Y + i++ +l+ k+++++ + k+ v+l vG G G l a ka +++ +++ + + ++ +++ e+ FUN_001172-T1 202 ENDDAYFSSYAHSgIHEEMLKDKTRTESYRdfvlnnpmifKDKVVLDVGCGTGILSMFAAKA-----GARHVIGIDQSDIIYQAMDIVKENGLESV 292 67777788886533666555544444444459999999999999999****99885544443.....34468999999999999999999999999 PP PRMT5 119 veiissdmreleaee.kvdllvsELlGsf 146 v++++ + +++ + kvd+++sE +G f FUN_001172-T1 293 VTLVKGKVENVTLPVnKVDVIISEWMGYF 321 ************9977***********88 PP >> Methyltransf_32 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.00022 0.22 26 94 .. 243 305 .. 233 332 .. 0.81 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00022 Methyltransf_32 26 eltlvDvGaGkgYLgfilydllkekelkvrvlgidvreelvekaeelaeklgfekrlsfaelsvaeate 94 ++ ++DvG+G g L+ + ++ + + +v+gid + +++ +a+++ ++ g+e+ + +++v++ t FUN_001172-T1 243 DKVVLDVGCGTGILSMFAAK-----AGARHVIGIDQS-DIIYQAMDIVKENGLESVVTLVKGKVENVTL 305 56899**********99999.....6689******76.5666777888888887777777777777766 PP >> Methyltransf_4 Putative methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.1 0.00052 0.53 2 53 .. 243 292 .. 242 312 .. 0.78 2 ? -0.6 0.0 1.1 1.1e+03 16 44 .. 491 519 .. 487 522 .. 0.84 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00052 Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirkkvvakvlkkiealelkNl 53 +vvl++GcG G l+ A k ++Gi+ ++++ ++++ +++++l+ + FUN_001172-T1 243 DKVVLDVGCGTGI-LSMFAAKAGARHVIGIDQ-SDIIYQAMDIVKENGLESV 292 579********96.566677777889****96.6789999999999976655 PP == domain 2 score: -0.6 bits; conditional E-value: 1.1 Methyltransf_4 16 lvalAkknPdknflGiEirkkvvakvlkk 44 l + + k+P + + iE + kv++k+l++ FUN_001172-T1 491 LCTKSIKDPRSLDITIEAHDKVTQKILCH 519 6666778999999************9986 PP >> DUF7248 Family of unknown function (DUF7248) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 0.00022 0.23 34 52 .. 276 294 .. 271 296 .. 0.91 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00022 DUF7248 34 vaykvvdaiqenGLksVve 52 ++y+++d+++enGL sVv FUN_001172-T1 276 IIYQAMDIVKENGLESVVT 294 79***************96 PP >> Cons_hypoth95 Conserved hypothetical protein 95 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00028 0.29 40 83 .. 241 287 .. 232 352 .. 0.76 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00028 Cons_hypoth95 40 iegarvLDlfaGsGalglEAlSRgakkvvlvekdkkavk...ilken 83 ++++ vLD+ +G+G l++ A+ ga++v+ +++++ ++ i+ken FUN_001172-T1 241 FKDKVVLDVGCGTGILSMFAAKAGARHVIGIDQSDIIYQamdIVKEN 287 57899*****************************9766611155555 PP >> zf-C2H2_2 C2H2 type zinc-finger (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.4 0.00013 0.13 2 29 .. 33 60 .. 31 82 .. 0.82 2 ? -2.2 0.5 6.9 7e+03 3 54 .. 354 405 .. 350 420 .. 0.65 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00013 zf-C2H2_2 2 Clfcekeskeveenlehmskkhglfipe 29 Clfc+k +k++e++ +h s++hg++i + FUN_001172-T1 33 CLFCDKCFKNAEDVWRHCSSAHGVDIIK 60 ***********************99974 PP == domain 2 score: -2.2 bits; conditional E-value: 6.9 zf-C2H2_2 3 lfcekeskeveenlehmskkhglfipereylvdleglleylrekisekleCl 54 + +s++v++ l + + +g+ ++ ++ v e +e++++k + + +C FUN_001172-T1 354 FAALGNSERVQRKLGFWDNVYGFKMSCMKTSVCTEPSIEIVNHKDEISSRCT 405 4444556668888888888899888855555555555555555555555665 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 3.7 0.014 14 2 24 .] 32 54 .. 31 54 .. 0.92 2 ? 0.3 0.1 2.3 2.3e+03 2 13 .. 349 360 .. 349 365 .. 0.73 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.014 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 C +C+k F++ ++ rH + H FUN_001172-T1 32 LCLFCDKCFKNAEDVWRHCSSAH 54 5*****************98877 PP == domain 2 score: 0.3 bits; conditional E-value: 2.3 zf-C2H2_4 2 kCpiCgksFssk 13 +C+iC + ++ FUN_001172-T1 349 RCKICFAALGNS 360 6****8876665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (525 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1187 (0.046467); expected 510.9 (0.02) Passed bias filter: 810 (0.0317087); expected 510.9 (0.02) Passed Vit filter: 96 (0.00375807); expected 25.5 (0.001) Passed Fwd filter: 26 (0.00101781); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 25 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 4945.22 // Query: FUN_001173-T1 [L=461] Description: FUN_001173 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-20 71.9 1.5 3.1e-15 57.0 0.4 3.1 3 Ank_2 Ankyrin repeats (3 copies) 3e-13 49.7 2.0 1.6e-07 31.7 0.1 4.2 4 Ank Ankyrin repeat 8.6e-12 45.6 0.4 6.8e-06 26.8 0.1 2.7 2 Ank_5 Ankyrin repeats (many copies) 3.2e-11 43.7 0.2 2.6e-05 24.9 0.1 2.7 2 Ank_4 Ankyrin repeats (many copies) 6.7e-10 38.7 0.1 0.00016 22.3 0.0 3.6 3 Ank_3 Ankyrin repeat 1.6e-09 38.2 15.6 4.2e-09 36.8 15.6 1.8 1 zf-MYND MYND finger 0.00011 22.7 13.7 0.00025 21.6 13.7 1.6 1 MYND_ZMYND11_ZMYD8 ZMYND11/ZMYD8, MYND zinc finger ------ inclusion threshold ------ 0.058 12.7 0.2 0.12 11.7 0.2 1.4 1 Oxidored_nitro Nitrogenase component 1 type Oxidoreducta 0.092 12.9 0.1 0.49 10.6 0.1 2.1 1 Ank_KRIT1 KRIT1 ankyrin-repeats domain Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.0 0.4 1.1e-18 3.1e-15 8 89 .. 47 133 .. 40 134 .. 0.89 2 ! 21.9 0.0 9.9e-08 0.00028 30 79 .. 105 156 .. 100 164 .. 0.90 3 ? -2.1 0.0 3 8.7e+03 12 65 .. 305 324 .. 270 335 .. 0.57 Alignments for each domain: == domain 1 score: 57.0 bits; conditional E-value: 1.1e-18 Ank_2 8 gnl.elvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn...dnngrtaLhyAaesghleivklLlekgadinak 89 gn e++klL ++ +n++d+ g+t+L++Aa++g++e+++lL+++gadvn +++++t L++++ sg++++ ++Lle ga +na+ FUN_001173-T1 47 GNDqEVLKLLNlPDVRVNCLDEHGMTPLMCAAYKGKAEMCELLIAQGADVNsnyHEHQYTSLMFSCLSGSVDATRVLLEAGARVNAE 133 5443899999569999999999************************98888757788***************************987 PP == domain 2 score: 21.9 bits; conditional E-value: 9.9e-08 Ank_2 30 etaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklL 79 t L++++ +g++++ ++Lle ga vn +n grta ++ a g+ ++v l+ FUN_001173-T1 105 YTSLMFSCLSGSVDATRVLLEAGARVNaeNNLGRTAAQLGAFVGQTDCVSLI 156 799******************99888887899*********99******864 PP == domain 3 score: -2.1 bits; conditional E-value: 3 Ank_2 12 lvklLlegadanlqdkngetaLhlAaknghleivklLlehgadvndnngrtaLh 65 ++ k L++ a v ++g+ + FUN_001173-T1 305 IF--------------------------------KQLVQTIAPV--EKGQDPTA 324 23................................4444431111..23333333 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 4.1 1.2e+04 13 21 .. 48 56 .. 44 67 .. 0.71 2 ! 31.7 0.1 5.7e-11 1.6e-07 1 30 [. 69 98 .. 69 99 .. 0.94 3 ! 13.6 0.0 3.3e-05 0.094 3 33 .] 105 135 .. 103 135 .. 0.92 4 ? 0.3 0.0 0.57 1.6e+03 2 20 .. 137 155 .. 136 159 .. 0.87 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 4.1 Ank 13 ghlevvklL 21 ++ ev+klL FUN_001173-T1 48 NDQEVLKLL 56 558999988 PP == domain 2 score: 31.7 bits; conditional E-value: 5.7e-11 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvna 30 +G+TPL++Aa++g e+++lL+ +GAdvn FUN_001173-T1 69 HGMTPLMCAAYKGKAEMCELLIAQGADVNS 98 7*********99**********77****95 PP == domain 3 score: 13.6 bits; conditional E-value: 3.3e-05 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnardk 33 +T L+ + g+++ + LL++GA vna ++ FUN_001173-T1 105 YTSLMFSCLSGSVDATRVLLEAGARVNAENN 135 799*****99**********99******997 PP == domain 4 score: 0.3 bits; conditional E-value: 0.57 Ank 2 GnTPLHlAaraghlevvkl 20 G+T+ l a g++++v l FUN_001173-T1 137 GRTAAQLGAFVGQTDCVSL 155 89999999999******96 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.1 2.4e-09 6.8e-06 6 43 .. 60 97 .. 55 99 .. 0.91 2 ! 19.9 0.1 3.5e-07 0.00098 1 55 [. 89 143 .. 89 143 .. 0.93 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 2.4e-09 Ank_5 6 padlnrldgegytpLhvAakygaleivrlLlangvdln 43 ++++n+ld++g+tpL+ Aa++g +e+ +lL+a g+d+n FUN_001173-T1 60 DVRVNCLDEHGMTPLMCAAYKGKAEMCELLIAQGADVN 97 799*****************************999998 PP == domain 2 score: 19.9 bits; conditional E-value: 3.5e-07 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldl 55 L++ g +++ n+ +++ yt L++ + g+ + r+Ll+ g+ +n+ ++ g t+ +l FUN_001173-T1 89 LIAQGaDVNSNY-HEHQYTSLMFSCLSGSVDATRVLLEAGARVNAENNLGRTAAQL 143 788898899988.6799***********************************9876 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.1 9.1e-09 2.6e-05 6 50 .] 45 90 .. 40 90 .. 0.85 2 ! 16.2 0.0 5.1e-06 0.015 6 48 .. 113 155 .. 107 156 .. 0.93 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 9.1e-09 Ank_4 6 ksghlellklLlen.gadinatdgngetaLhfAasngnlevlklLl 50 +g+ + + Ll+ ++ +n++d+ g+t+L +Aa++g e+++lL+ FUN_001173-T1 45 NKGNDQEVLKLLNLpDVRVNCLDEHGMTPLMCAAYKGKAEMCELLI 90 567777777778888899***************************8 PP == domain 2 score: 16.2 bits; conditional E-value: 5.1e-06 Ank_4 6 ksghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 sg +++ + Lle ga +na ++ g+ta + a+ g++++++l FUN_001173-T1 113 LSGSVDATRVLLEAGARVNAENNLGRTAAQLGAFVGQTDCVSL 155 5899***********************************9975 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 4.5 1.3e+04 3 28 .. 37 62 .. 35 65 .. 0.64 2 ! 22.3 0.0 5.7e-08 0.00016 1 30 [. 69 97 .. 69 98 .. 0.96 3 ! 12.4 0.0 9.6e-05 0.27 2 31 .] 104 132 .. 103 132 .. 0.93 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 4.5 Ank_3 3 ntpLhlAarngrle.ivklLleklgad 28 + +L+ g+ + ++klL + + FUN_001173-T1 37 EKLLFSHLNKGNDQeVLKLLNL-PDVR 62 5677777888888646766655.5555 PP == domain 2 score: 22.3 bits; conditional E-value: 5.7e-08 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+tpL++Aa g+ e+++lL+ +gad+n FUN_001173-T1 69 HGMTPLMCAAYKGKAEMCELLIA-QGADVN 97 79*********************.****99 PP == domain 3 score: 12.4 bits; conditional E-value: 9.6e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 +t L++ +++g++++ ++Lle ga +na FUN_001173-T1 104 QYTSLMFSCLSGSVDATRVLLE-AGARVNA 132 79********************.9999885 PP >> zf-MYND MYND finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.8 15.6 1.5e-12 4.2e-09 1 39 [] 344 381 .. 344 381 .. 0.95 Alignments for each domain: == domain 1 score: 36.8 bits; conditional E-value: 1.5e-12 zf-MYND 1 CavCgk.ealkllrCsrCksvrYCskeCqkadwkkHkkeC 39 C vC + ++ k +Cs+Ck v YCs Cqk +w++Hkk C FUN_001173-T1 344 CVVCTEkRNVK--KCSSCKMVGYCSVRCQKLHWSTHKKFC 381 999*9977777..*************************** PP >> MYND_ZMYND11_ZMYD8 ZMYND11/ZMYD8, MYND zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 13.7 8.9e-08 0.00025 1 35 [] 344 381 .. 344 381 .. 0.80 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 8.9e-08 MYND_ZMYND11_ZMYD8 1 CakCekeAiy.yC..CwntsYCskeCQqkhWkeHkktC 35 C+ C ++ +C C YCs+ CQ+ hW++Hkk C FUN_001173-T1 344 CVVCTEKRNVkKCssCKMVGYCSVRCQKLHWSTHKKFC 381 777765443325655999*******************9 PP >> Oxidored_nitro Nitrogenase component 1 type Oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.2 4.2e-05 0.12 60 139 .. 307 396 .. 305 416 .. 0.86 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 4.2e-05 Oxidored_nitro 60 ekLkeaikevvkrykpkaIfVistClaeliGdDieavvreareeegkipvipvstpgf.vgshseGydaalealveklik.........k 139 ++L ++i v k + p+a +V++ + +l D+ +++ +e+++ +++ +++ g+ + ++ ++++ ++++++l+k FUN_001173-T1 307 KQLVQTIAPVEKGQDPTALAVLTQTVNGLRCADFSGCCVVCTEKRNVKKCSSCKMVGYcSVRCQKLHWSTHKKFCKQLAKeyekelalkL 396 6899*************************************9999999**********999999**************886666666652 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.1 0.00017 0.49 19 70 .. 37 94 .. 26 143 .. 0.73 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00017 Ank_KRIT1 19 deeLrkaaakGdeetvariLn...vrekvddpes...lvaAakgGheevlqlLlalGk 70 ++ L + +kG+ + v ++Ln vr ++ d + l+ Aa G+ e+ +lL+a G FUN_001173-T1 37 EKLLFSHLNKGNDQEVLKLLNlpdVRVNCLDEHGmtpLMCAAYKGKAEMCELLIAQGA 94 555667778999999999998444566666655556689999************9994 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (461 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1611 (0.0630652); expected 510.9 (0.02) Passed bias filter: 623 (0.0243883); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4445.49 // Query: FUN_001174-T1 [L=190] Description: FUN_001174 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-31 107.5 0.0 8.6e-31 107.2 0.0 1.1 1 DHFR_1 Dihydrofolate reductase Domain annotation for each model (and alignments): >> DHFR_1 Dihydrofolate reductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.2 0.0 3.3e-35 8.6e-31 2 159 .] 8 188 .. 7 188 .. 0.84 Alignments for each domain: == domain 1 score: 107.2 bits; conditional E-value: 3.3e-35 DHFR_1 2 islivAvdengvIGkdnklpw.hlpeDlkrFkkltlg.......kpvimGRktfeslg...kpLpnRknivltrnkdlkve.gvevvksleealal 85 +s+++A+++n+ IG+++klpw +l++Dl+++ ++t+ ++v+ GRkt+e + +p p+R niv++++ ++ + ++v++s+ +a+++ FUN_001174-T1 8 VSCVAAMASNRGIGNKGKLPWpSLRTDLEFLERKTITvkdkgkwNAVLFGRKTWEGIDisqRPFPGRLNIVISKSLKTPPRgSHHVCDSVLSAVKM 103 689******************77*******9887764333334468**********97778**************998887456688999888876 PP DHFR_1 86 akkk......eevfiiGGaeiykqllp..ladklylteidaefegdtffPeideeewelvsreeeekd...eknkyeltfvtyer 159 +++ e +f++GG e+y+++++ ++++ylteid+ef++d+ffP +d+++++l+s+ + ++ e+n +++++++yer FUN_001174-T1 104 LSAPpfsstvEGIFVLGGTEVYREAIEssFCHRIYLTEIDKEFDADAFFPVFDKSRYKLISNPSDVHEgviEENGVQYRICVYER 188 555445555799*************963369*****************************9876655434478999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (190 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 440 (0.0172245); expected 510.9 (0.02) Passed bias filter: 414 (0.0162067); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1917.56 // Query: FUN_001175-T1 [L=616] Description: FUN_001175 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-55 188.6 4.8 3.6e-55 188.1 4.8 1.1 1 MFS_1_like MFS_1 like family 9.3e-12 45.0 32.6 1.9e-07 30.8 4.8 2.5 3 MFS_1 Major Facilitator Superfamily 0.00098 18.5 8.8 0.01 15.2 7.1 3.1 3 LacY_symp LacY proton/sugar symporter 0.0093 16.6 0.7 0.0093 16.6 0.7 3.2 3 DUF5657 Family of unknown function (DUF5657) ------ inclusion threshold ------ 0.033 13.1 2.7 0.051 12.5 2.7 1.2 1 MFS_3 Transmembrane secretion effector Domain annotation for each model (and alignments): >> MFS_1_like MFS_1 like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 188.1 4.8 7.1e-59 3.6e-55 5 327 .. 52 571 .. 49 578 .. 0.91 Alignments for each domain: == domain 1 score: 188.1 bits; conditional E-value: 7.1e-59 MFS_1_like 5 kifYFfyfaalgallPYlglyLkslglspaeigillailpltrilapniwgvlaDrlgkrkavvllalvlaavlflslllp............... 85 k+fYFf++ alg+l+P+++++ k+l l+p +ig+lla++p+++++ ++w +++Dr+ k k v ++++ +++ + + + FUN_001175-T1 52 KAFYFFFYTALGSLFPFFSVFYKQLWLTPGQIGLLLALRPAVKLVCLPLWKMVSDRYSKPKVVYFISIFGWIIGYFGQSFVypsnlpcysfskegf 147 89***********************************************************************999766333699*********** PP MFS_1_like 86 ................................................................................................ 85 FUN_001175-T1 148 ivqtsnisaspptqinssatnfqknissrglledsllphslpkwdpkiyqdlnkrgkenvrlidnlkstktkagsqgllsqlngrdttviyanaks 243 ************************************************************************************************ PP MFS_1_like 86 ..........................................................................................lektfw 91 + +f FUN_001175-T1 244 erqrvesvessppkgnikdktedglsfedsgdetkrdamnnvaimkrrlmadsaspriiekknsdvikpyekvgdlspsprplddfrvkfNVWIFR 339 ***************************************************************************************776666677 PP MFS_1_like 92 vlallvvlfsffwnailallevatleklgekrkdYgrirlwGsiGfavsvfllGilidtlsvellpvv......llvllaalllislllvlileek 181 l l+v+l ++++ ++ +l+++a+ + l e++ +Yg++rl+Gs+G +++++l+ + + + l++ ++l+ + + +++ ++ ++++ FUN_001175-T1 340 CLTLIVILTEIITTPTPMLADSAIVQSLVETKSEYGKQRLFGSLGLGLAAILVAVWVSVST-DCLHTDtinylpCFYLFEIAIGATVWVSFFVKFD 434 789999****************************************999988877664332.2333222343354444444333333332223333 PP MFS_1_like 182 kyesklkivkeektavseaeksllkvlkqpeviifllvalllgisvgiiynFlslYLeqlgasktllGalvalgvvaeiplflvaerllrrlGhvk 277 + + ++v + + ++ + + +fl++++ g+++++ y+Fl++YL++lg ++ l ++++ + ++ae+++++++ ++ +G + FUN_001175-T1 435 RPLGE--------ENVAYDFLDGMRLFTNFRNGVFLVTLFSFGFFHSLHYSFLFWYLQDLGGTPVLFSIILLMYCLAEVATYFLSGHVVDAIGQQG 522 32222........23444568899************************************************************************ PP MFS_1_like 278 llilallltalrflllavlaeslwlvllielLhalsfglvwaaaieyvrk 327 +++la++ + +rfl++++l +++w+v+++el +++++g vw+ a yv+ FUN_001175-T1 523 MICLAFACYTARFLMYSYL-KNAWFVIPMELVQGITYGGVWSIAAVYVNA 571 *******************.***************************984 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.8 4.8 3.8e-11 1.9e-07 5 83 .. 55 135 .. 53 142 .. 0.90 2 ? 1.2 0.6 0.038 1.9e+02 266 316 .. 375 430 .. 338 444 .. 0.65 3 ! 19.4 19.7 1.1e-07 0.00056 129 320 .. 380 570 .. 374 576 .. 0.73 Alignments for each domain: == domain 1 score: 30.8 bits; conditional E-value: 3.8e-11 MFS_1 5 aflaalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrfGrrr.vlllglllfalglllll.fa..s 83 +f+++++ + l+p+++ + ++l ++p +iglll+l ++ ++ +l+ +sdr+++ + v++++++++++g +++ f+ s FUN_001175-T1 55 YFFFYTALGSLFPFFS-VFYKQLWLTPGQIGLLLALRPAVKLVCLPLWKMVSDRYSKPKvVYFISIFGWIIG-YFGQsFVypS 135 89**************.88899**********************************9999************.7777665434 PP == domain 2 score: 1.2 bits; conditional E-value: 0.038 MFS_1 266 grrrrlllallllllaalgllllslt....esslwlll.allllGfgfglv.fplll 316 g+ +rl+ +l+l+l+a l +++s++ ++ ++ +l +++l+ +++g++ +++++ FUN_001175-T1 375 GK-QRLFGSLGLGLAAILVAVWVSVStdclHTDTINYLpCFYLFEIAIGATvWVSFF 430 43.555555555555555556666556787666666666777788855444255554 PP == domain 3 score: 19.4 bits; conditional E-value: 1.1e-07 MFS_1 129 gfglGaalGpllggllaslfg..........wravFlilailallaavlaalllprpppeskrkkpaeeapapllpawkallrdpvlwlllalllf 214 + +lG l+++l ++ +s + +l+ ++++ + v +++ +++p +++ + + +++ ++ +++ +l++l++f FUN_001175-T1 380 FGSLGLGLAAILVAVWVSVSTdclhtdtinyLPCFYLFEIAIGATVWVS-FFVKFDRPLGEENVAY-D-FLDGMRL-FTNFRNGV---FLVTLFSF 468 6667777777766666644447888888774344444555555555442.2222333333333322.2.2344444.77788888...9******* PP MFS_1 215 glaffalltllplyqevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgllllsltesslwlllallllGfgfgl 310 g++ ++ +++l++y ++lg + +l +++l +++l+ +++ +l+g ++d +g + +++l++++ ++ +l+ s+++++++++ + l+ G+++g FUN_001175-T1 469 GFFHSLHYSFLFWYLQDLGGT-PVLFSIILLMYCLAEVATYFLSGHVVDAIG---QQGMICLAFACYTARFLMYSYLKNAWFVIPMELVQGITYGG 560 **************9999999.6999999*********************77...6888999999999999999999777777779999******* PP MFS_1 311 vfplllalvs 320 v+++++++v FUN_001175-T1 561 VWSIAAVYVN 570 **99999875 PP >> LacY_symp LacY proton/sugar symporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 7.1 2e-06 0.01 7 88 .. 46 125 .. 41 139 .. 0.83 2 ! 11.5 0.0 2.6e-05 0.13 129 167 .. 363 401 .. 332 418 .. 0.83 3 ? -4.3 7.9 1.7 8.5e+03 21 318 .. 470 550 .. 450 577 .. 0.49 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2e-06 LacY_symp 7 tnfylfalffffyffimsayfplfpvwlkevlglsktetGivfsvislfsilfqplfGlisdklGlkkellwvislllvlfa 88 ++f++ f+ff++ ++ fp+f+v+ k+ l l+ +++G++ + + ++ pl+ ++sd+ ++++ is++ +++ FUN_001175-T1 46 KSFFVSKAFYFFFYTALGSLFPFFSVFYKQ-LWLTPGQIGLLLALRPAVKLVCLPLWKMVSDRYSK-PKVVYFISIFGWIIG 125 579999999*****************9986.68******************************974.556777777554444 PP == domain 2 score: 11.5 bits; conditional E-value: 2.6e-05 LacY_symp 129 iekvsraskfeyGkarvfGclGyalcaslaGilfsidps 167 i + ++k eyGk r+fG+lG l+a l + s++ + FUN_001175-T1 363 IVQSLVETKSEYGKQRLFGSLGLGLAAILVAVWVSVSTD 401 4444455678*********************99999865 PP == domain 3 score: -4.3 bits; conditional E-value: 1.7 LacY_symp 21 fimsayfplfpvwlkevlglsktetGivfsvislfsilfqplfGlisdklGlkkellwvislllvlfapffiyvfepllqlnilvGalvGgvflGl 116 f s++++++ +l++ + i+ + l + l G + d +G + + ++++ +a f++y + FUN_001175-T1 470 FFHSLHYSFLFWYLQDLG-GTPVLFSIILLMYCLAEVATYFLSGHVVDAIGQQGMI--CLAF-ACYTARFLMYSYL-------------------- 541 335666666654454432.2333344444444444455555566666666654433..3332.2456666666654.................... PP LacY_symp 117 vysagagaieayiekvsraskfeyGkarvfGclGyalcaslaGilfsidpslvfwlasgfalilllllllskpdksssakvadalGankeafslrl 212 FUN_001175-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP LacY_symp 213 alelfkdrklwvfvlyvvGvasvydvfdqqfavffkslfespeaGtrvfGyvttagellnalimfiaplivnriGaknalliagvimsvrilgsaf 308 FUN_001175-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP LacY_symp 309 attalevvil 318 ++a+ v+ + FUN_001175-T1 542 -KNAWFVIPM 550 .333333322 PP >> DUF5657 Family of unknown function (DUF5657) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.85 4.4e+03 40 55 .. 378 393 .. 364 398 .. 0.70 2 ? -2.4 0.3 1.5 7.9e+03 48 56 .. 492 500 .. 489 503 .. 0.51 3 ! 16.6 0.7 1.8e-06 0.0093 16 48 .. 577 609 .. 576 610 .. 0.93 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.85 DUF5657 40 kllallhlllalllll 55 +l++ l l+la++l+ FUN_001175-T1 378 RLFGSLGLGLAAILVA 393 5777788888866654 PP == domain 2 score: -2.4 bits; conditional E-value: 1.5 DUF5657 48 llallllll 56 l++++ll++ FUN_001175-T1 492 LFSIILLMY 500 344444444 PP == domain 3 score: 16.6 bits; conditional E-value: 1.8e-06 DUF5657 16 FalvvvrQvklMnktletplspllkllallhll 48 l++v Q++ +++tl+tpl++++ l +++ ++ FUN_001175-T1 577 IVLLIVLQTSRLKDTLTTPLNWVVSLTSWVLFC 609 5799**************************997 PP >> MFS_3 Transmembrane secretion effector # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 2.7 9.9e-06 0.051 186 330 .. 425 567 .. 377 578 .. 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 9.9e-06 MFS_3 186 llrwkreakasslpreklleavraglRftkasrelrsvlvRavvFglsasavlaLLPlvardlldgdalvyGilLgavGvGailgalllsrLRerl 281 ++ + ++ l +e++ + +g+R + lv + Fg + s ++ L ++l+g ++ + i+L + +++ l+ ++ + + FUN_001175-T1 425 VWVSFFVKFDRPLGEENVAYDFLDGMRLFTNF-RNGVFLVTLFSFGFFHSLHYSFLFWYL-QDLGGTPVLFSIILLMYCLAEVATYFLSGHVVDAI 518 333344556788999************65543.446778888999999999999997665.669******************************** PP MFS_3 282 dsdklvllasvvlalvllalalasnlwlavlvlllsGaaWilalttlnv 330 +++ ++ la++ + + l+ + ++n+w ++++ l+ G ++ +++ v FUN_001175-T1 519 GQQGMICLAFACYTARFLMYSYLKNAWFVIPMELVQGITYGGVWSIAAV 567 ********************************99998877777766544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (616 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 791 (0.030965); expected 510.9 (0.02) Passed bias filter: 473 (0.0185163); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5953.39 // Query: FUN_001176-T1 [L=947] Description: FUN_001176 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-112 376.6 0.9 2e-112 376.2 0.9 1.2 1 Glyco_hydro_31_2nd Glycosyl hydrolases family 31 TIM-barrel 7.8e-31 106.9 0.0 2e-30 105.6 0.0 1.8 1 Glyco_hydro_31_3rd Glycosyl hydrolase family 31 C-terminal d 2.3e-11 43.9 2.7 2.3e-11 43.9 2.7 1.7 2 Trefoil Trefoil (P-type) domain 2.1e-09 38.4 0.2 1.6e-08 35.5 0.2 2.2 2 Gal_mutarotas_2 Glycosyl hydrolase 31 N-terminal galactos 0.0056 16.8 0.0 0.26 11.5 0.0 2.4 2 Ubiquitin_UBP8 UBP8-like, ubiquitin-like domain ------ inclusion threshold ------ 0.066 13.7 0.0 0.23 12.0 0.0 2.0 2 DUF5110 Domain of unknown function (DUF5110) 0.15 12.6 0.0 0.71 10.4 0.0 2.2 2 Golvesin_C Golvesin C-terminal domain Domain annotation for each model (and alignments): >> Glyco_hydro_31_2nd Glycosyl hydrolases family 31 TIM-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 376.2 0.9 5.5e-116 2e-112 1 328 [] 312 683 .. 312 683 .. 0.96 Alignments for each domain: == domain 1 score: 376.2 bits; conditional E-value: 5.5e-116 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 1 palppkwalGyhqsrwgykseeevkevvekfreadiPldviwlDidymdktrdftwdperFpdpkemvkelhekglklvvivdpgiskkee 91 p lpp+w+lG+++srwgy+ e+vk++v+ +r++diP dv++ Didym++++dft+dp +F+ +e+v++++++gl++++i+dp+i ++++ FUN_001176-T1 312 PFLPPYWSLGFQLSRWGYNRIETVKNLVKSMRQYDIPQDVQYGDIDYMTRQKDFTYDPANFKGLPEFVQSIKKDGLRYIIILDPAIGANDS 402 689***********************************************************99************************999 PP xxxxxxxxxxxxxxxxxxxxx.xxxxx.xxx.....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 92 syevydegkekgvfvknkdgs.lyvgk.wpg.....................ssafpDftnpearewwkeelkkfllelgvdgiwiDmnEp 159 +y++yd g+e +vf+k+ d++ +++gk wp ++ fpD+++p+ e+w + +k+f+ +++dg+wiDmnEp FUN_001176-T1 403 NYQPYDLGNELNVFIKDGDTGgNLYGKvWPLlqnvvvntslpwdeqtrlyrqHATFPDYFHPNISEYWGKLIKDFHKIIEFDGLWIDMNEP 493 ****************988777889999*8777888889999999999*999999*****************999988************* PP xxxx.xxxx.xxxxxxxxxxxxx....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 160 snfe.gsep.eekaakdndegkg....................vehydvhnlygllmakatyeglrekkpkkrpfvlsRstfaGsqryaah 228 +nf g+ ++k+++d++++k+ hy+vh+lyg++++ t e+ r+ + kr++v+sRstf++s++ya+h FUN_001176-T1 494 ANFVkGKVGgCSKNSWDYPPYKPriignimadktvcmnakqasDIHYNVHSLYGWSQTLITIEAARNS-TGKRSVVISRSTFPSSGKYAGH 583 ********9*********99988******************98789******************8776.7********************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 229 WsGDnastwehlresipgllslglsGipfvgaDiGGFanteseeLlvRWvqlGaFsPffrnHsskdtkrqepwafgeeveeiirkaiklRy 319 W+GDn+++w++l++si g+l+++l+Gip++gaD++GF++ +++e++ RW+qlGaF+Pf+rnH+ ++k q+p afg e+++ +rk++++Ry FUN_001176-T1 584 WLGDNKASWDQLHKSIIGMLEFNLFGIPYIGADVCGFFDHPTKEMCLRWTQLGAFYPFSRNHNGFGNKAQDPTAFGVEFARDARKVLQIRY 674 **************************************7778************************************************* PP xxxxxxxxx RF Glyco_hydro_31_2nd 320 rLlPylYtl 328 rLlP+lYtl FUN_001176-T1 675 RLLPFLYTL 683 *******97 PP >> Glyco_hydro_31_3rd Glycosyl hydrolase family 31 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.6 0.0 5.6e-34 2e-30 1 87 [] 691 778 .. 691 778 .. 0.96 Alignments for each domain: == domain 1 score: 105.6 bits; conditional E-value: 5.6e-34 Glyco_hydro_31_3rd 1 gepvlrplflefpedeetfaiddqfllGdsLLvaPvleegatsvkvyLPegkWydyftgekyeggkev.evtapldkiplfvrgGsIi 87 g++v+rpl++efp+++ t++id+qfl+G++LL++Pvle+g+tsv++y+P+++Wy+y+tg++++ ++++ ++ap d+ipl+vrgG+Ii FUN_001176-T1 691 GSTVVRPLMHEFPKENVTWEIDRQFLWGPNLLISPVLEKGKTSVEAYFPDSRWYNYYTGKEMHTRQRHvILHAPRDRIPLHVRGGHII 778 789********************************************************9999977555999***************9 PP >> Trefoil Trefoil (P-type) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.9 2.7 6.2e-15 2.3e-11 3 43 .] 35 76 .. 34 76 .. 0.94 2 ? -3.3 0.0 3.4 1.2e+04 12 23 .. 618 630 .. 617 631 .. 0.87 Alignments for each domain: == domain 1 score: 43.9 bits; conditional E-value: 6.2e-15 Trefoil 3 svppseRvdCgy..pgiteeeCeargCCydpsvkpgvpwCFyp 43 svp+++++dC y g+++++C++rgC + + ++ g+pwCF+p FUN_001176-T1 35 SVPDQSKIDC-YpeMGASRASCQSRGCTWEEISEKGIPWCFFP 76 59********.75889**************************8 PP == domain 2 score: -3.3 bits; conditional E-value: 3.4 Trefoil 12 Cgy.pgiteeeCe 23 Cg+ t+e C FUN_001176-T1 618 CGFfDHPTKEMCL 630 99999999**996 PP >> Gal_mutarotas_2 Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.5 0.2 4.5e-12 1.6e-08 34 182 .. 135 270 .. 105 271 .. 0.74 2 ? -0.4 0.0 0.44 1.6e+03 12 82 .. 839 912 .. 829 929 .. 0.58 Alignments for each domain: == domain 1 score: 35.5 bits; conditional E-value: 4.5e-12 Gal_mutarotas_2 34 ekeekveveveeeedelilsteklkvveikkepfrisfy.rdgklvlsdndggllnfehlrgkewedskpkgpesvaldf.slppdehvyGlGE 125 ++++++ev v + + + ++ k +ve+k +pf ++++ +d+ vl d + g++ fe+ +l++ + pp+ v+G+GE FUN_001176-T1 135 SRNKRYEVPVPMPKATEKAVNPKY-KVEFKSDPFYLKISrKDNGAVLWDSSVGVFIFED----------------QYLQIsTKPPSSFVFGFGE 211 444444444444444444444544.666***********99999999999999******................44666255666899***** PP Gal_mutarotas_2 126 kagplnlrgt....ryrlwntDvfeygaestdplYksiPfylslrkg.rgyGvFwdntaetw 182 + + +++ + +++ D ++ ++ +lY+++Pfy ++ +++GvF++n+ ++ FUN_001176-T1 212 QEHKSFKHNLsaweVLPIFTRD--QFP-FNGGNLYGHHPFYTCMENDgKAHGVFLLNSNAME 270 8665544444599999******..555.55***********9888766*********98765 PP == domain 2 score: -0.4 bits; conditional E-value: 0.44 Gal_mutarotas_2 12 lrvreapkg.efeedpswav...eeeekeekveveveeeedelilsteklkvveikkepfrisfyrdgklvlsdn 82 +r+ +++g ++++ p+w + + + +v++ ++++++ ++ +++++v ++ +++++++++++ +++ FUN_001176-T1 839 IRFNLVKNGyAARDLPKWGLitvFGLDAGGVDSVSIGQTDTKANFNFNSESKV-LTITDLSLNLNEEHEIKWTVS 912 56664444446667777777776444444555566666666666666666555.666666666664443333333 PP >> Ubiquitin_UBP8 UBP8-like, ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.0 7.2e-05 0.26 12 42 .. 167 197 .. 159 198 .. 0.91 2 ? 2.6 0.0 0.043 1.6e+02 29 46 .. 881 898 .. 879 902 .. 0.84 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 7.2e-05 Ubiquitin_UBP8 12 LvvkIskkDNavelfkrAckIFsvesellrI 42 + kIs+kDN + l++ + +F +e + l+I FUN_001176-T1 167 FYLKISRKDNGAVLWDSSVGVFIFEDQYLQI 197 678************************9998 PP == domain 2 score: 2.6 bits; conditional E-value: 0.043 Ubiquitin_UBP8 29 AckIFsvesellrIWDFS 46 A F++es++l I D S FUN_001176-T1 881 ANFNFNSESKVLTITDLS 898 5556************99 PP >> DUF5110 Domain of unknown function (DUF5110) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 3.8 1.4e+04 30 50 .. 548 571 .. 547 582 .. 0.61 2 ? 12.0 0.0 6.2e-05 0.23 3 45 .. 796 840 .. 794 852 .. 0.80 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 3.8 DUF5110 30 yatteitvdd...dggtltltiga 50 +++t it+++ + g++++ i+ FUN_001176-T1 548 WSQTLITIEAarnSTGKRSVVISR 571 566666666644444777777764 PP == domain 2 score: 12.0 bits; conditional E-value: 6.2e-05 DUF5110 3 tlrvy...ggegsftlYeDDGetyd.YekGeyatteitvdddggtlt 45 l v +g+++ +l+ DDGe+ d ekGey ++++ +d +++ FUN_001176-T1 796 GLLVAlgdDGKARGELFWDDGESIDtMEKGEYLLISLFCDG--TGIR 840 678888777778888**********889******9998888..5555 PP >> Golvesin_C Golvesin C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00019 0.71 40 103 .. 125 190 .. 118 199 .. 0.83 2 ? -3.5 0.0 3.9 1.4e+04 65 85 .. 532 554 .. 529 570 .. 0.67 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00019 Golvesin_C 40 sdtatwtlnipasGtYeVsvwypaasnratnapytvatsggsttvtvnqqanggr.W.vsLgsfsl 103 +d ++++l +++ +YeV v +p+a+++a n +y+v+ +++ ++ + ng+ W s+g f + FUN_001176-T1 125 EDRLRFKLYDSRNKRYEVPVPMPKATEKAVNPKYKVEFKSDPFYLKISRKDNGAVlWdSSVGVFIF 190 566777888888899***********************************9998624335666666 PP == domain 2 score: -3.5 bits; conditional E-value: 3.9 Golvesin_C 65 snratnapytvatsgg..sttvt 85 +++a++ +y+v++ g +t +t FUN_001176-T1 532 AKQASDIHYNVHSLYGwsQTLIT 554 67889999999987774233344 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (947 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 520 (0.0203562); expected 510.9 (0.02) Passed bias filter: 499 (0.0195342); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.40 # Mc/sec: 9455.86 // Query: FUN_001177-T1 [L=1422] Description: FUN_001177 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1422 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3679 (0.14402); expected 510.9 (0.02) Passed bias filter: 830 (0.0324917); expected 510.9 (0.02) Passed Vit filter: 467 (0.0182815); expected 25.5 (0.001) Passed Fwd filter: 94 (0.00367978); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 1.41u 0.45s 00:00:01.86 Elapsed: 00:00:00.51 # Mc/sec: 11163.17 // Query: FUN_001177-T2 [L=1619] Description: FUN_001177 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1619 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3954 (0.154786); expected 510.9 (0.02) Passed bias filter: 916 (0.0358583); expected 510.9 (0.02) Passed Vit filter: 478 (0.0187121); expected 25.5 (0.001) Passed Fwd filter: 93 (0.00364063); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 1.43u 0.53s 00:00:01.96 Elapsed: 00:00:00.52 # Mc/sec: 12555.93 // Query: FUN_001178-T1 [L=467] Description: FUN_001178 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-112 376.6 1.2 2.8e-112 376.4 1.2 1.0 1 Tcp11 T-complex protein 11 ------ inclusion threshold ------ 0.059 14.1 0.1 0.2 12.4 0.1 1.9 1 GA GA module Domain annotation for each model (and alignments): >> Tcp11 T-complex protein 11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 376.4 1.2 2.2e-116 2.8e-112 1 433 [. 30 459 .. 30 460 .. 0.93 Alignments for each domain: == domain 1 score: 376.4 bits; conditional E-value: 2.2e-116 Tcp11 1 LrhEiafdpelqfrpnld..geegrvketmakayWdalreeleedppdysrllalleeirdiLlsllkp.pnrlrqqIeevLDvelikqqlekgvl 93 L+hE+++++++++ ++l ++e+rv++ ++ka+Wd+l eel+ dpp ++++l+l+ e+++ +lsll+p +++lr+qI+evLD++likqq+++g+l FUN_001178-T1 30 LAHELLMNDSFRLASELPenSLEKRVRDVVHKAFWDKLGEELSHDPPVFNQALSLMGEVKENILSLLLPhHSSLRAQINEVLDLDLIKQQANHGIL 125 89************988899*************************************************9************************** PP Tcp11 94 dieklaeflasllkklCAPmRDeevkklvekikssvdklVegLralfeiLelMklDvaNhqirslrplLieeaveYErkkFqerlekgkislestk 189 di +la+f++s+l+klCAP+RD++vkk+ + +++V++++++f+ ++ Mk+D+aN+q+++++p+L+ ++veYErkkF+e l++++ +l stk FUN_001178-T1 126 DIPRLAQFVVSVLSKLCAPARDDQVKKIL-HN----ENIVDLFKEVFSLMDGMKVDMANFQLQTIKPHLLLQSVEYERKKFKEYLQSNPAALLSTK 216 ***************************99.33....45********************************************************** PP Tcp11 190 kWlkkareellaeaaerdeegss.sessasssp.......spakvlaqglldllsssdpsseeefPetlllDeaRlrelraelrqlvvlaavlllf 277 +Wlk+ + +++++++++++ s +e+++++ + + ++vl++g+l +++ p ++Petl +De Rl e+r +r+ +++a+v+l++ FUN_001178-T1 217 AWLKRGA-KAATSTDSTSPAEMSdEEKETTD-FkqklrdvNLTEVLVHGYLGIIFGE-P--GWPYPETLIMDEFRLAEMRWSVRRTTLIASVVLVA 307 ******6.44555555555555524444444.3599999989**************5.5..458******************************** PP Tcp11 278 knllkrdvsssrsfwkklksrilalledeeske.kealesialeivrevskslkeegtlpempeatkawLrkqiqklleksnpvfkllesrlreal 372 n+++++++s++ +++lk+ + +ll++ + + ++al ++ +++v+e++k l+ +g ++++ + +k++L++qi+ + +++n+v+k++++r +e++ FUN_001178-T1 308 LNTIGQQLASDTVYLASLKEVLYILLDGVTEGDfSSALCGVYEQLVKETEKLLEARGLSQLTQQ-QKEMLKGQIEGISSPDNTVYKVISNRSYEFM 402 ****************************9877676778999*******99999****9995555.******************************* PP Tcp11 373 larllaesasekvkaastaseklapaGlaefveeveeiaerlarlvnvhwrvfgpwYeeil 433 l+r+ + + ++++ + +++++p+Gl+++ +e++ei++r+ r+v ++ +vf p+Ye+il FUN_001178-T1 403 LSRMKS----RLHRESGQSTSPSIPQGLTSVNTELSEITSRFLRVVGHNMAVFTPFYEDIL 459 ***999....5566688889999************************************97 PP >> GA GA module # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 1.6e-05 0.2 17 34 .. 364 381 .. 361 388 .. 0.92 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.6e-05 GA 17 gLtgLNdaQkqalknqin 34 gL++L+++Qk+ lk qi+ FUN_001178-T1 364 GLSQLTQQQKEMLKGQIE 381 79***************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (467 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 956 (0.0374242); expected 510.9 (0.02) Passed bias filter: 650 (0.0254453); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 4616.66 // Query: FUN_001178-T2 [L=308] Description: FUN_001178 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-61 208.4 0.1 3.5e-61 208.1 0.1 1.0 1 Tcp11 T-complex protein 11 ------ inclusion threshold ------ 0.054 14.2 0.1 0.12 13.1 0.1 1.5 1 GA GA module Domain annotation for each model (and alignments): >> Tcp11 T-complex protein 11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 208.1 0.1 2.7e-65 3.5e-61 138 433 .. 6 300 .. 2 301 .. 0.90 Alignments for each domain: == domain 1 score: 208.1 bits; conditional E-value: 2.7e-65 Tcp11 138 alfeiLelMklDvaNhqirslrplLieeaveYErkkFqerlekgkislestkkWlkkareellaeaaerdeegss.sessasssp.......spak 225 ++f+ ++ Mk+D+aN+q+++++p+L+ ++veYErkkF+e l++++ +l stk+Wlk+ + +++++++++++ s +e+++++ + + ++ FUN_001178-T2 6 EVFSLMDGMKVDMANFQLQTIKPHLLLQSVEYERKKFKEYLQSNPAALLSTKAWLKRGA-KAATSTDSTSPAEMSdEEKETTD-FkqklrdvNLTE 99 799*******************************************************6.44555555555555524444444.3599999989** PP Tcp11 226 vlaqglldllsssdpsseeefPetlllDeaRlrelraelrqlvvlaavlllfknllkrdvsssrsfwkklksrilalledeeske.kealesiale 320 vl++g+l +++ p ++Petl +De Rl e+r +r+ +++a+v+l++ n+++++++s++ +++lk+ + +ll++ + + ++al ++ ++ FUN_001178-T2 100 VLVHGYLGIIFGE-P--GWPYPETLIMDEFRLAEMRWSVRRTTLIASVVLVALNTIGQQLASDTVYLASLKEVLYILLDGVTEGDfSSALCGVYEQ 192 ************5.5..458************************************************************9877676778999*** PP Tcp11 321 ivrevskslkeegtlpempeatkawLrkqiqklleksnpvfkllesrlreallarllaesasekvkaastaseklapaGlaefveeveeiaerlar 416 +v+e++k l+ +g ++++ + +k++L++qi+ + +++n+v+k++++r +e++l+r+ + + ++++ + +++++p+Gl+++ +e++ei++r+ r FUN_001178-T2 193 LVKETEKLLEARGLSQLTQQ-QKEMLKGQIEGISSPDNTVYKVISNRSYEFMLSRMKS----RLHRESGQSTSPSIPQGLTSVNTELSEITSRFLR 283 ****99999****9995555.**********************************999....5566688889999********************* PP Tcp11 417 lvnvhwrvfgpwYeeil 433 +v ++ +vf p+Ye+il FUN_001178-T2 284 VVGHNMAVFTPFYEDIL 300 ***************97 PP >> GA GA module # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.1 9.4e-06 0.12 17 34 .. 205 222 .. 201 229 .. 0.92 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 9.4e-06 GA 17 gLtgLNdaQkqalknqin 34 gL++L+++Qk+ lk qi+ FUN_001178-T2 205 GLSQLTQQQKEMLKGQIE 222 79***************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (308 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1133 (0.0443531); expected 510.9 (0.02) Passed bias filter: 825 (0.0322959); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3018.33 // Query: FUN_001179-T1 [L=279] Description: FUN_001179 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-33 113.3 14.3 2.5e-11 44.0 1.9 3.8 3 SapB_2 Saposin-like type B, region 2 4e-24 84.7 12.7 1.4e-11 44.7 3.8 3.4 2 SapB_1 Saposin-like type B, region 1 1.1e-12 48.6 10.7 7.2e-06 26.5 1.5 3.2 3 Saposin Saposin-like domain 6.4e-06 26.5 0.6 6.4e-06 26.5 0.6 3.2 3 SapA Saposin A-type domain 4.9e-05 23.9 0.4 0.027 15.1 0.1 2.5 2 PWI_CCDC43 CCDC43 PWI-like domain 0.00048 20.6 0.3 1.1 9.7 0.0 2.3 2 mTOR_dom Serine/threonine-protein kinase mTOR domain 0.0028 17.5 1.0 1.1 9.1 0.1 2.1 2 TPR_AP5Z1 AP-5 complex subunit zeta-1, TPR repeats 0.0068 16.8 0.0 4.2 7.8 0.0 2.3 2 HD_3 HD domain ------ inclusion threshold ------ 0.03 15.1 0.0 2 9.1 0.1 2.8 3 DUF1722 Protein of unknown function (DUF1722) 0.032 14.3 0.0 0.064 13.3 0.0 1.5 1 HB_ELP1 ELP1 three-helix bundle 0.044 14.0 0.0 2.6 8.2 0.0 2.1 2 MOR2-PAG1_C Cell morphogenesis C-terminal 0.058 14.3 0.1 21 6.1 0.0 2.5 2 COMMD8_HN COMMD8, helical N-terminal domain 0.058 13.3 0.2 0.071 13.0 0.2 1.2 1 V-ATPase_H_N V-ATPase subunit H 0.07 13.9 0.2 1.8 9.4 0.1 2.4 2 RPN6_N 26S proteasome regulatory subunit RPN6 N-termin 0.19 11.8 0.1 7.3 6.6 0.0 2.1 2 PP2C_2 Protein phosphatase 2C 0.21 11.5 0.8 3.5 7.5 0.0 2.1 2 GlfB_C GlfB-like, C-terminal domain Domain annotation for each model (and alignments): >> SapB_2 Saposin-like type B, region 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.3 0.9 2.3e-13 3.6e-10 2 34 .] 1 34 [. 1 34 [. 0.98 2 ! 44.0 1.9 1.6e-14 2.5e-11 2 34 .] 117 149 .. 116 149 .. 0.97 3 ! 36.1 0.2 4.4e-12 7.1e-09 2 34 .] 213 244 .. 212 244 .. 0.98 Alignments for each domain: == domain 1 score: 40.3 bits; conditional E-value: 2.3e-13 SapB_2 2 eCkslVdqYgplIidlLengld.PkdvCtalglC 34 +CkslVdqY+p+I++++ + + P++vCtalglC FUN_001179-T1 1 MCKSLVDQYAPVIMSNIDKLMAdPQKVCTALGLC 34 6********************************* PP == domain 2 score: 44.0 bits; conditional E-value: 1.6e-14 SapB_2 2 eCkslVdqYgplIidlLengldPkdvCtalglC 34 C+++V+qY p I++lL++++dP vCt+lg+C FUN_001179-T1 117 DCDQFVQQYEPAIVELLLQEIDPAMVCTMLGVC 149 5******************************** PP == domain 3 score: 36.1 bits; conditional E-value: 4.4e-12 SapB_2 2 eCkslVdqYgplIidlLengldPkdvCtalglC 34 eC+++V +Y+p I+dl+ + dP++ C ++glC FUN_001179-T1 213 ECNAIVTEYAPAILDLIATA-DPHTLCEEIGLC 244 9******************8.************ PP >> SapB_1 Saposin-like type B, region 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.7 1.6 1.7e-14 2.8e-11 2 38 .] 75 111 .. 74 111 .. 0.97 2 ! 44.7 3.8 8.5e-15 1.4e-11 2 38 .] 171 207 .. 170 207 .. 0.98 Alignments for each domain: == domain 1 score: 43.7 bits; conditional E-value: 1.7e-14 SapB_1 2 lCdlCefvVkeveklLkdnkTeeeIieaLekvCskLP 38 C lCe+v++ ++ L++n+T+eeI+eaLe+vCs++P FUN_001179-T1 75 ACILCEYVITTLKGILSENSTKEEIEEALEDVCSLFP 111 5**********************************99 PP == domain 2 score: 44.7 bits; conditional E-value: 8.5e-15 SapB_1 2 lCdlCefvVkeveklLkdnkTeeeIieaLekvCskLP 38 +C++Ce++++++++ L dn+T++eI+++++++C++LP FUN_001179-T1 171 TCEVCETAMTYLKNILADNATKQEILDLMKQICNYLP 207 8***********************************9 PP >> Saposin Saposin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.6 0.2 0.0032 5.2 44 83 .. 2 42 .. 1 74 [. 0.75 2 ! 26.5 1.5 4.5e-09 7.2e-06 4 80 .. 75 154 .. 72 181 .. 0.83 3 ! 20.0 0.3 4.7e-07 0.00075 23 86 .. 195 257 .. 171 273 .. 0.80 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0032 Saposin 44 cyllvevfGsdiikllekdm.nadvvchtlefckqeagqpl 83 c lv+ + + i+ ++k m +++ vc +l++c + +++ FUN_001179-T1 2 CKSLVDQYAPVIMSNIDKLMaDPQKVCTALGLCTSQVKKTV 42 8889999******999998845799********98776654 PP == domain 2 score: 26.5 bits; conditional E-value: 4.5e-09 Saposin 4 gcvvvvsvieqlaqv..hnst...vkaalerlcsylpeklflkttcyllvevfGsdiikllekdmnadvvchtlefckqeag 80 +c++ vi+ l + nst +++ale +cs +p+ +++ c v+ + + i+ ll +++++ +vc l++c + FUN_001179-T1 75 ACILCEYVITTLKGIlsENSTkeeIEEALEDVCSLFPDT--IRSDCDQFVQQYEPAIVELLLQEIDPAMVCTMLGVCASKEH 154 677777777777665336777444679**********97..6899********************************87654 PP == domain 3 score: 20.0 bits; conditional E-value: 4.7e-07 Saposin 23 vkaalerlcsylpeklflkttcyllvevfGsdiikllekdmnadvvchtlefc..kqeagqplchl 86 + + ++++c+ylp +l c +v+ + + i+ l+ + ++ +c +++c k++ g +c l FUN_001179-T1 195 ILDLMKQICNYLPSQL--APECNAIVTEYAPAILDLIAT-ADPHTLCEEIGLCsdKKKGGGDFCFL 257 3346899******986..5789**************976.5899*********6667788999988 PP >> SapA Saposin A-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.2 0.62 9.8e+02 20 31 .. 27 38 .. 26 39 .. 0.85 2 ? -1.4 0.0 2.1 3.4e+03 17 24 .. 210 217 .. 208 218 .. 0.79 3 ! 26.5 0.6 4e-09 6.4e-06 4 22 .. 255 273 .. 252 276 .. 0.91 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.62 SapA 20 eCgAvkHCqqkv 31 C A+ C ++v FUN_001179-T1 27 VCTALGLCTSQV 38 5*******9876 PP == domain 2 score: -1.4 bits; conditional E-value: 2.1 SapA 17 tAkeCgAv 24 A eC+A+ FUN_001179-T1 210 LAPECNAI 217 5889**96 PP == domain 3 score: 26.5 bits; conditional E-value: 4e-09 SapA 4 CtwGpsyWCqdletAkeCg 22 C +G s+WC++ ++A++C+ FUN_001179-T1 255 CFLGASFWCANKQNAVKCN 273 ******************9 PP >> PWI_CCDC43 CCDC43 PWI-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.1 1.7e-05 0.027 29 69 .. 86 125 .. 78 129 .. 0.81 2 ! 6.3 0.0 0.0094 15 27 69 .. 180 221 .. 176 225 .. 0.81 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.7e-05 PWI_CCDC43 29 IlGiLeeeeseeEkkeaLegiLseiteedieevckeIlekW 69 ++GiL+e++++eE +eaLe++ s + ++i + c++ ++++ FUN_001179-T1 86 LKGILSENSTKEEIEEALEDVCSLF-PDTIRSDCDQFVQQY 125 69******************98866.456666677776666 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0094 PWI_CCDC43 27 sYIlGiLeeeeseeEkkeaLegiLseiteedieevckeIlekW 69 +Y++ iL ++ +++E + +++i + + +++ c+ I++++ FUN_001179-T1 180 TYLKNILADNATKQEILDLMKQICNY-LPSQLAPECNAIVTEY 221 79***************999999765.4566777788888776 PP >> mTOR_dom Serine/threonine-protein kinase mTOR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.0 0.00068 1.1 85 137 .. 80 133 .. 39 147 .. 0.87 2 ! 9.2 0.1 0.001 1.6 75 143 .. 166 236 .. 137 241 .. 0.77 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00068 mTOR_dom 85 tvvinaLlkilkdpslsshhtavvqaimsifkt.lglkcvpflpqiipallsvi 137 +vi++L il+++s ++ +++++ + s f + +++ c +f++q pa+++++ FUN_001179-T1 80 EYVITTLKGILSENSTKEEIEEALEDVCSLFPDtIRSDCDQFVQQYEPAIVELL 133 689****************************75499*******99999988764 PP == domain 2 score: 9.2 bits; conditional E-value: 0.001 mTOR_dom 75 lspss.eeyyptvvinaLlkilkdpslsshhtavvqaimsifkt.lglkcvpflpqiipallsvirtces.s 143 + + + e+++t +++ L +il d++ ++ + ++ i + + + l +c +++++ pa+l +i t+++ + FUN_001179-T1 166 VGSNEtCEVCET-AMTYLKNILADNATKQEILDLMKQICNYLPSqLAPECNAIVTEYAPAILDLIATADPhT 236 333332555555.999*************9999999999888665889999999999********9999844 PP >> TPR_AP5Z1 AP-5 complex subunit zeta-1, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.1 0.1 0.00067 1.1 101 174 .. 46 120 .. 11 126 .. 0.77 2 ! 7.1 0.1 0.0027 4.3 92 172 .. 136 214 .. 127 221 .. 0.78 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00067 TPR_AP5Z1 101 lsldeiq.dtkllslvasvllaqaekkeevssvgqrvlkvlesRqpegqslrhlLpvlskvislspesltedqvn 174 l +d+ +++l +v++++ k + +++ v+ +l + ++e+++ + + l++v sl p++++ d + FUN_001179-T1 46 LIFDSLPlKKHLFAPKKTVIISKPYKASAACILCEYVITTLKGILSENSTKEEIEEALEDVCSLFPDTIRSDCDQ 120 444444413344566889**************************************************9998655 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0027 TPR_AP5Z1 92 elspsdelslsldeiqdtkllslvasvllaqaekkeevssvgqrvlkvlesRqpegqslrhlLpvlskvislspesltedq 172 e+ p ++ +++ + + l v+l +++ e +v+++ + l + ++++ + + +L +++++ ++ p++l + FUN_001179-T1 136 EIDPAMVCTMLGVCASKEHRKALEKKVVLKVGSN--ETCEVCETAMTYLKNILADNATKQEILDLMKQICNYLPSQLAPEC 214 5555555555555555666677778888887755..6799**********************************9998765 PP >> HD_3 HD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.9 0.0 0.0048 7.6 73 110 .. 90 127 .. 82 170 .. 0.86 2 ! 7.8 0.0 0.0026 4.2 73 109 .. 186 222 .. 174 226 .. 0.86 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0048 HD_3 73 vakkekeerekeaaerilkllpeelaeellalweefee 110 +++++ +e+ +ea e++++l p+ ++ ++ ++++++e FUN_001179-T1 90 LSENSTKEEIEEALEDVCSLFPDTIRSDCDQFVQQYEP 127 66777889999*************************96 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0026 HD_3 73 vakkekeerekeaaerilkllpeelaeellalweefe 109 +a+++ +++ + +++i++ lp++la e+ a+++e+ FUN_001179-T1 186 LADNATKQEILDLMKQICNYLPSQLAPECNAIVTEYA 222 5667777888999***********************6 PP >> DUF1722 Protein of unknown function (DUF1722) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2.4 3.8e+03 29 66 .. 4 42 .. 2 46 .. 0.64 2 ? 2.4 0.0 0.16 2.5e+02 32 75 .. 80 123 .. 65 165 .. 0.68 3 ? 9.1 0.1 0.0013 2 33 80 .. 153 201 .. 148 212 .. 0.76 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.4 DUF1722 29 elaeeYeellmealkk.katrkshinvlqhilGyfkkkl 66 +l+++Y +m+ + k a +++++ +l + ++kk++ FUN_001179-T1 4 SLVDQYAPVIMSNIDKlMADPQKVCTALGLCTSQVKKTV 42 567777777777664425667777777776666666665 PP == domain 2 score: 2.4 bits; conditional E-value: 0.16 DUF1722 32 eeYeellmealkkkatrkshinvlqhilGyfkkklsseekqell 75 e + l+ +l++++t+++ ++l+ ++ f +++ s+ q ++ FUN_001179-T1 80 EYVITTLKGILSENSTKEEIEEALEDVCSLFPDTIRSDCDQFVQ 123 45567777788888888888888888888887777666555443 PP == domain 3 score: 9.1 bits; conditional E-value: 0.0013 DUF1722 33 eYeellmealkkkatrkshinvlqhilGyfkkkl.sseekqelleliek 80 e +++l++ + k +++++v++ ++ y+k+ l +++ kqe+l+l+++ FUN_001179-T1 153 EHRKALEKKVVLKVGSNETCEVCETAMTYLKNILaDNATKQEILDLMKQ 201 6677778888888888888999999999999887246678888888876 PP >> HB_ELP1 ELP1 three-helix bundle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 4e-05 0.064 88 150 .. 147 211 .. 140 227 .. 0.74 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 4e-05 HB_ELP1 88 sarssknRRkaerKkysLKeGsplE.dl..AlleaLaeiirkvdklkeevhsllkaLvlfefdeqa 150 + +sk Rka +Kk LK Gs ++ ++ L++i + +++k+e+ +l+k++ ++ + a FUN_001179-T1 147 GVCASKEHRKALEKKVVLKVGSNETcEVceTAMTYLKNI-LADNATKQEILDLMKQICNYLPSQLA 211 5679******************74223311234445554.456889**********9998766555 PP >> MOR2-PAG1_C Cell morphogenesis C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.0016 2.6 135 192 .. 95 153 .. 79 166 .. 0.81 2 ? 3.9 0.0 0.033 53 185 244 .. 164 218 .. 160 224 .. 0.80 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0016 MOR2-PAG1_C 135 eeeg.leslarvltsyakgkfrskkdflkqvvsalreaffpeleaqilvfllgllenkt 192 ++e+ e+l+ v + + + +++++f++q a+ e ++e + +++ +lg+ k+ FUN_001179-T1 95 TKEEiEEALEDVCSLFPDTIRSDCDQFVQQYEPAIVELLLQEIDPAMVCTMLGVCASKE 153 3333478888888888888888*******************************876654 PP == domain 2 score: 3.9 bits; conditional E-value: 0.033 MOR2-PAG1_C 185 lgllenktswvkvktlqiLkvllpeidlrkpeiaslgadlispllrllqtelakeAleVL 244 l++ +n+t v ++++ Lk +l + ++ +ei dl++ ++ +l ++la+e + FUN_001179-T1 164 LKVGSNETCEVCETAMTYLKNILADNATK-QEI----LDLMKQICNYLPSQLAPECNAIV 218 55667888888899999999999998888.667....59999999999999999877665 PP >> COMMD8_HN COMMD8, helical N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.019 31 41 71 .. 76 106 .. 62 117 .. 0.84 2 ? 6.1 0.0 0.013 21 36 71 .. 167 202 .. 147 212 .. 0.81 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.019 COMMD8_HN 41 lelleslkslfkkavkkklskeevleeLsel 71 + l+e + +++k +++++++kee+ e+L+++ FUN_001179-T1 76 CILCEYVITTLKGILSENSTKEEIEEALEDV 106 6688889999******************986 PP == domain 2 score: 6.1 bits; conditional E-value: 0.013 COMMD8_HN 36 sleeWlelleslkslfkkavkkklskeevleeLsel 71 ++e +e++e +++k++++ + +k+e+l+ ++++ FUN_001179-T1 167 GSNETCEVCETAMTYLKNILADNATKQEILDLMKQI 202 567899************************999986 PP >> V-ATPase_H_N V-ATPase subunit H # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.2 4.5e-05 0.071 73 201 .. 78 211 .. 34 250 .. 0.82 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.5e-05 V-ATPase_H_N 73 ivqyvLvliadllsedpsraklflelskkeekkpyspflkllerq.defivllalrllakllaegkkksnelv.........eeaLnlllslLskl 158 +++yv ++++ +lse+ + +++ ++l++ + s f +++ ++ d+f+++ ++ ll e + + ++ +aL++ +++ k FUN_001179-T1 78 LCEYVITTLKGILSENSTKEEIEEALED-----VCSLFPDTIRSDcDQFVQQYEPAIVELLLQEIDPAMVCTMlgvcaskehRKALEK--KVVLKV 166 579************9877765555333.....8999999888887999999999999999999999999966888885444444443..236679 PP V-ATPase_H_N 159 lssetlqlqeiavrclqellrtkeyRklfwk..aegvsllldllr 201 s+et+++ e+a++ l+++l ++ ++ +++ ++++++l++ l FUN_001179-T1 167 GSNETCEVCETAMTYLKNILADNATKQEILDlmKQICNYLPSQLA 211 999****************************99999999999884 PP >> RPN6_N 26S proteasome regulatory subunit RPN6 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.37 5.9e+02 5 41 .. 95 132 .. 81 134 .. 0.64 2 ? 9.4 0.1 0.0011 1.8 23 66 .. 165 207 .. 148 218 .. 0.77 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.37 RPN6_N 5 aksdpkkaeelykeilskks.sedeealreqEqalleL 41 +k++ ++a e ++ ++ s+ ++ ++++E a++eL FUN_001179-T1 95 TKEEIEEALEDVCSLFPDTIrSDCDQFVQQYEPAIVEL 132 34455555555555555555455567888888888877 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0011 RPN6_N 23 kssedeealreqEqalleLgelyrdqkkaeeLaelikesrsfls 66 k++ ++e+ + E+a++ L ++++d+ ++e+ +l+k++ ++l FUN_001179-T1 165 KVG-SNETCEVCETAMTYLKNILADNATKQEILDLMKQICNYLP 207 333.34589999**************************999885 PP >> PP2C_2 Protein phosphatase 2C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.0045 7.3 40 108 .. 71 153 .. 67 159 .. 0.54 2 ? 3.2 0.0 0.051 82 46 96 .. 173 221 .. 165 242 .. 0.66 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0045 PP2C_2 40 SevGariaveavvealsdlleeeele..deallrallnallaav.........lkeeaear...eleprdlatTllaavatpd 108 +a+i++e v+ +l+ l+e +++ +e++l+++++ + +++ + e a ++ ++ ++ +T+l + a+++ FUN_001179-T1 71 KASAACILCEYVITTLKGILSENSTKeeIEEALEDVCSLFPDTIrsdcdqfvqQYEPAIVElllQEIDPAMVCTMLGVCASKE 153 5678****************666655555555555554433333333354443122222222221122245666666666665 PP == domain 2 score: 3.2 bits; conditional E-value: 0.051 PP2C_2 46 iaveavvealsdlleeeele..deallrallnallaavlkeeaeareleprdl 96 ++e+++ +l++ l + +++ + +l+++++n l +++ a ++ + + ++ FUN_001179-T1 173 EVCETAMTYLKNILADNATKqeILDLMKQICNYLPSQL----APECNAIVTEY 221 6899**********666655457777888877766544....44444444444 PP >> GlfB_C GlfB-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.0022 3.5 53 107 .. 69 125 .. 53 131 .. 0.84 2 ? 2.2 0.2 0.091 1.5e+02 89 127 .. 163 201 .. 128 208 .. 0.72 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0022 GlfB_C 53 ekysveetl..kevvselisaldekelkeklkeefeesfkyikkkeegdvatflkky 107 + ++ ++ + v+++l l+e+++ke+++e++e++ + +d+ +f+++y FUN_001179-T1 69 PYKASAACIlcEYVITTLKGILSENSTKEEIEEALEDVCSLFPDTIRSDCDQFVQQY 125 5555555556688999999***********************************999 PP == domain 2 score: 2.2 bits; conditional E-value: 0.091 GlfB_C 89 fkyikkkeegdvatflkkylaevfkedslvllvlKtltQ 127 + ++e ++v ++ +yl++ +++++ +l + Q FUN_001179-T1 163 VLKVGSNETCEVCETAMTYLKNILADNATKQEILDLMKQ 201 3457889999***********999999887777666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (279 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1124 (0.0440008); expected 510.9 (0.02) Passed bias filter: 772 (0.0302212); expected 510.9 (0.02) Passed Vit filter: 78 (0.00305344); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.37u 0.36s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 2727.70 // Query: FUN_001180-T1 [L=1842] Description: FUN_001180 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-24 85.9 0.1 6.7e-24 84.6 0.1 1.7 1 ARID ARID/BRIGHT DNA binding domain 1.3e-15 58.3 0.0 2.4e-15 57.4 0.0 1.5 1 RFX_DNA_binding RFX DNA-binding domain 0.00012 22.2 4.0 0.00018 21.6 1.0 2.5 2 Zap1_zf1 Zap1, C2H2 zinc finger 1 0.00054 20.9 3.5 0.41 11.7 0.4 2.7 2 FOXP-CC FOXP coiled-coil domain Domain annotation for each model (and alignments): >> ARID ARID/BRIGHT DNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.6 0.1 1.1e-27 6.7e-24 2 90 .] 25 110 .. 24 110 .. 0.96 Alignments for each domain: == domain 1 score: 84.6 bits; conditional E-value: 1.1e-27 ARID 2 keeFlkqLkkfhekrgtplkkiPkiggkpldLykLykaVqkrGGyekvtkkkkWrevaeklglppeqskatsaatqlkkiYekyLlpye 90 ++ F+++Lk+fhe++gtp++++P +gg+ ldLy Ly+ V++ GG+ kvt+ k+Wr++ae ++lpp+ +t+aa++l+++Y +yL ++e FUN_001180-T1 25 YNGFMAKLKNFHETKGTPFRRLPWLGGQYLDLYLLYRKVTSAGGWVKVTEGKMWRDIAEVFNLPPT---CTNAAFALRQHYSRYLEKFE 110 678****************99******************************************965...699****************8 PP >> RFX_DNA_binding RFX DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.4 0.0 3.8e-19 2.4e-15 2 78 .. 539 616 .. 538 617 .. 0.96 Alignments for each domain: == domain 1 score: 57.4 bits; conditional E-value: 3.8e-19 RFX_DNA_binding 2 kfalqwlkknyeeaedvsvpRsevYaeYvstcsklkl.kplnaasfgklvravFpnlktRRLgtrGqskYhYvglrlk 78 +f+ +wl+ +ye ++++sv+R ++Ya+Y+s+cskl++ +lna+ f +++++ Fp+ + RR+ + + +Y+ g+++k FUN_001180-T1 539 AFTYSWLQGTYEASPGSSVSRIDIYADYLSSCSKLARvGILNATAFNRIIKVAFPDGQLRRVTSGVNVQYVLAGIKRK 616 7999******************************9988*************************999*********987 PP >> Zap1_zf1 Zap1, C2H2 zinc finger 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 1.0 2.9e-08 0.00018 2 27 .] 1656 1681 .. 1655 1681 .. 0.97 2 ? 0.8 0.1 0.095 6.1e+02 2 9 .. 1689 1696 .. 1688 1713 .. 0.84 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 2.9e-08 Zap1_zf1 2 kCkWddCsesFsnlidLqkHvlkdHv 27 C+W+ C sF++ L +Hv ++Hv FUN_001180-T1 1656 RCRWTACCSSFDTSKTLFSHVVNEHV 1681 5************************9 PP == domain 2 score: 0.8 bits; conditional E-value: 0.095 Zap1_zf1 2 kCkWddCs 9 C W C+ FUN_001180-T1 1689 SCLWEGCP 1696 6******8 PP >> FOXP-CC FOXP coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 0.4 6.4e-05 0.41 6 34 .. 1656 1684 .. 1652 1688 .. 0.92 2 ! 9.2 0.2 0.00039 2.5 6 31 .. 1689 1714 .. 1687 1717 .. 0.94 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 6.4e-05 FOXP-CC 6 vCkWPgCekvledveeflkHlqseHsldd 34 C+W C + +++ +++++H+ +eH + d FUN_001180-T1 1656 RCRWTACCSSFDTSKTLFSHVVNEHVPRD 1684 6************************9887 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00039 FOXP-CC 6 vCkWPgCekvledveeflkHlqseHs 31 C W gC v ++ +++l Hlq++Hs FUN_001180-T1 1689 SCLWEGCPPVRRSRSSLLFHLQQKHS 1714 6************************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1842 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 699 (0.0273635); expected 510.9 (0.02) Passed bias filter: 455 (0.0178117); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.52u 0.40s 00:00:00.92 Elapsed: 00:00:00.42 # Mc/sec: 17772.80 // Query: FUN_001180-T2 [L=1164] Description: FUN_001180 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-05 23.5 4.0 0.00011 22.3 1.0 2.5 2 Zap1_zf1 Zap1, C2H2 zinc finger 1 0.00021 22.2 3.5 0.25 12.4 0.4 2.6 2 FOXP-CC FOXP coiled-coil domain ------ inclusion threshold ------ 0.34 11.8 1.1 0.77 10.7 0.2 2.0 2 Sina_ZnF Sina, zinc finger Domain annotation for each model (and alignments): >> Zap1_zf1 Zap1, C2H2 zinc finger 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 1.0 1.3e-08 0.00011 2 27 .] 978 1003 .. 977 1003 .. 0.97 2 ? 1.4 0.1 0.043 3.7e+02 2 9 .. 1011 1018 .. 1010 1035 .. 0.83 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 1.3e-08 Zap1_zf1 2 kCkWddCsesFsnlidLqkHvlkdHv 27 C+W+ C sF++ L +Hv ++Hv FUN_001180-T2 978 RCRWTACCSSFDTSKTLFSHVVNEHV 1003 5************************9 PP == domain 2 score: 1.4 bits; conditional E-value: 0.043 Zap1_zf1 2 kCkWddCs 9 C W C+ FUN_001180-T2 1011 SCLWEGCP 1018 6******8 PP >> FOXP-CC FOXP coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.4 0.4 2.9e-05 0.25 6 34 .. 978 1006 .. 974 1010 .. 0.92 2 ! 9.9 0.2 0.00017 1.5 6 31 .. 1011 1036 .. 1009 1039 .. 0.94 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.9e-05 FOXP-CC 6 vCkWPgCekvledveeflkHlqseHsldd 34 C+W C + +++ +++++H+ +eH + d FUN_001180-T2 978 RCRWTACCSSFDTSKTLFSHVVNEHVPRD 1006 6************************9887 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00017 FOXP-CC 6 vCkWPgCekvledveeflkHlqseHs 31 C W gC v ++ +++l Hlq++Hs FUN_001180-T2 1011 SCLWEGCPPVRRSRSSLLFHLQQKHS 1036 6************************8 PP >> Sina_ZnF Sina, zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.2 9.1e-05 0.77 33 64 .. 972 1002 .. 962 1011 .. 0.90 2 ? -2.3 0.0 1.1 9e+03 52 64 .. 1023 1035 .. 1007 1037 .. 0.69 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 9.1e-05 Sina_ZnF 33 CefrpysCpypgskCkwqGdldelvkHlrnkH 64 frp++C + C+ + ++l +H++n+H FUN_001180-T2 972 TSFRPFRCRWT-ACCSSFDTSKTLFSHVVNEH 1002 579*******7.99****************** PP == domain 2 score: -2.3 bits; conditional E-value: 1.1 Sina_ZnF 52 dldelvkHlrnkH 64 + ++l+ Hl++kH FUN_001180-T2 1023 SRSSLLFHLQQKH 1035 5678999999999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 652 (0.0255236); expected 510.9 (0.02) Passed bias filter: 380 (0.0148757); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.43u 0.40s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 10862.50 // Query: FUN_001181-T1 [L=528] Description: FUN_001181 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-86 289.0 0.1 8.8e-86 288.3 0.1 1.3 1 Fe_hyd_lg_C Iron only hydrogenase large subunit, C-terminal 1.3e-11 44.9 0.3 3.1e-11 43.7 0.3 1.6 1 Fe_hyd_SSU Iron hydrogenase small subunit ------ inclusion threshold ------ 0.026 15.2 0.0 0.054 14.2 0.0 1.5 1 DUF4275 Domain of unknown function (DUF4275) 0.028 14.7 0.7 0.054 13.8 0.7 1.4 1 FAD_syn FAD synthetase Domain annotation for each model (and alignments): >> Fe_hyd_lg_C Iron only hydrogenase large subunit, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 288.3 0.1 1.4e-89 8.8e-86 1 280 [] 160 454 .. 160 454 .. 0.95 Alignments for each domain: == domain 1 score: 288.3 bits; conditional E-value: 1.4e-89 Fe_hyd_lg_C 1 kkvvaqvAPavrvalgeefgleakvvtgklvaalkklGfdkvfdtafgadltimeeaeeflerlek.....geklpmitScCPawvklvekkype. 90 k ++++++P++r++++ +f+l +++ +kl++++k lG+++vfdt+f++d+++ e+++ef+erl++ ++ pm++S+CP+wv+++ek++ + FUN_001181-T1 160 KVIIVSISPQSRASVAVKFKLGLTETAQKLTKFFKDLGVQHVFDTTFSRDFSLAESQREFVERLKNfqdgeKNAIPMLASACPGWVCYAEKTHGSy 255 5689************************************************************55555556689******************998 PP Fe_hyd_lg_C 91 llpnlssvkSPmqmlGaliKkyyaekk..dpekivvVsimPCtaKKaEaareelkss....rdvDavlTtrElaelikeagidlakledeefdspl 180 +lp++s++kSP+q++G+l+K+y+a +p++i++V++mPC++KK+Ea+re++ ++ rdvD+v++t El+++++e+g+++ +le++e+d ++ FUN_001181-T1 256 ILPYISTTKSPQQIMGSLVKNYFATSLakSPDQIYHVTVMPCYDKKLEASREDFYNDiyrtRDVDCVISTVELEKMFEEKGVNFMELENTELDIQF 351 99************************999**************************978889********************************998 PP Fe_hyd_lg_C 181 gessgagri...fgatGGvmeavlrtayekltgkeleeiefkevrglegvkeaevelegke.vkvavvsGlknakkllekikagelkydfiEvmaC 272 ++ g + g +GG++e ++ +a+++ +k++++i++k++r++ ++ke +++++gk+ +k+a ++G++n+++l++kik+g+ +y+f+EvmaC FUN_001181-T1 352 SSVCGDELLshsGGGSGGYLEHIFTYAAKECFEKTVSDIKYKTLRNK-DFKEVTLQVDGKDeLKFAAAYGFRNIQNLVQKIKRGKSPYHFVEVMAC 446 888887766666999*******************************9.********9887527********************************* PP Fe_hyd_lg_C 273 pgGCigGg 280 p+GC++Gg FUN_001181-T1 447 PSGCLNGG 454 *******8 PP >> Fe_hyd_SSU Iron hydrogenase small subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.7 0.3 4.8e-15 3.1e-11 11 55 .. 475 516 .. 467 517 .. 0.88 Alignments for each domain: == domain 1 score: 43.7 bits; conditional E-value: 4.8e-15 Fe_hyd_SSU 11 lykidkskklrkSheNpavkklYeeflgeplsekahelLHThYta 55 ly +s++ r + eN++v +lY+++lg+ seka+++LHT+Y++ FUN_001181-T1 475 LY---NSLRTRNPSENQEVEQLYRKWLGGESSEKARKMLHTSYHE 516 45...44689*********************************97 PP >> DUF4275 Domain of unknown function (DUF4275) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 8.4e-06 0.054 47 81 .. 362 396 .. 330 416 .. 0.84 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 8.4e-06 DUF4275 47 knddgvcgylwhlfsyekrkclkgeeaekafdeee 81 ++ g gyl h+f+y ++c+++ ++ +++ + FUN_001181-T1 362 HSGGGSGGYLEHIFTYAAKECFEKTVSDIKYKTLR 396 4556788****************999888777655 PP >> FAD_syn FAD synthetase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.7 8.5e-06 0.054 25 100 .. 143 222 .. 141 227 .. 0.73 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 8.5e-06 FAD_syn 25 llkkakeiake...kglpsvvvtFephPrevlkkekaparLttleeklel.leelgvdallvlkFtkefael.saeeFiek 100 ++++ k+ a+e ++ ++++v +p+ r ++ k + Lt+ +kl++ +++lgv++++ ++F+++f+ s++eF+e+ FUN_001181-T1 143 VIANNKKLAEEgklEDKKVIIVSISPQSRASVA-VKFKLGLTETAQKLTKfFKDLGVQHVFDTTFSRDFSLAeSQREFVER 222 565555555541115667888888888888888.6666779*999998652799***************976156789987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (528 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1353 (0.0529654); expected 510.9 (0.02) Passed bias filter: 936 (0.0366412); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.42s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5118.99 // Query: FUN_001182-T1 [L=74] Description: FUN_001182 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (74 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 759 (0.0297123); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 740.10 // Query: FUN_001183-T1 [L=100] Description: FUN_001183 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.18 11.7 0.1 0.2 11.6 0.1 1.0 1 BBS1 Ciliary BBSome complex subunit 1 Domain annotation for each model (and alignments): >> BBS1 Ciliary BBSome complex subunit 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 7.9e-06 0.2 101 140 .. 26 66 .. 11 79 .. 0.81 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.9e-06 BBS1 101 kftlPsleinpeEeevWkklkeek.idleelleaLeklree 140 kf P+ + ++E+ W++++ee+ +++++l+ ++++++e+ FUN_001183-T1 26 KFLHPNEKNAKKERRSWTNYQEENiMEQNTLCMDMKTMEEN 66 9********************666378999*****999965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1440 (0.0563711); expected 510.9 (0.02) Passed bias filter: 867 (0.0339401); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 991.34 // Query: FUN_001184-T1 [L=960] Description: FUN_001184 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-121 405.1 6.0 7.2e-121 404.8 6.0 1.1 1 Adaptin_N Adaptin N terminal region 5.2e-59 198.3 0.0 1.5e-58 196.8 0.0 1.9 1 Coatomer_b_Cpla Coatomer beta subunit appendage platform 2.1e-56 190.1 0.3 4.8e-56 188.9 0.3 1.7 1 Coatamer_beta_C Coatomer beta C-terminal region 1.5e-11 43.9 0.6 0.027 15.2 0.0 5.5 5 HEAT HEAT repeat 2.5e-10 41.0 0.4 0.0029 18.3 0.0 6.3 7 HEAT_2 HEAT repeats 1e-08 35.9 8.5 1.5e-05 25.6 0.1 4.2 4 Cnd1 non-SMC mitotic condensation complex subunit 1.7e-08 35.3 0.3 0.2 12.7 0.0 5.8 6 HEAT_EZ HEAT-like repeat 9.9e-05 22.8 6.4 1.1 9.6 0.3 4.3 4 TPR_Trm732_C Trm732, C-terminal TPR repeats 0.00015 22.3 0.0 0.00041 20.9 0.0 1.8 1 Coatomer_g_Cpla Coatomer subunit gamma-1 C-terminal appendag 0.00066 20.1 0.4 1.6 9.4 0.0 4.7 5 Arm Armadillo/beta-catenin-like repeat 0.0011 18.9 0.3 1.6 8.5 0.0 3.3 3 TOR1L1_N TORTIFOLIA1 N-terminal 0.0019 18.3 0.3 0.23 11.5 0.0 3.2 3 MMS19_N Dos2-interacting transcription regulator of ------ inclusion threshold ------ 0.014 15.8 6.0 15 6.1 0.2 5.0 4 INTS1_R4 Integrator complex subunit 1, R4 domain Domain annotation for each model (and alignments): >> Adaptin_N Adaptin N terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 404.8 6.0 3.7e-124 7.2e-121 3 471 .. 20 497 .. 18 533 .. 0.93 Alignments for each domain: == domain 1 score: 404.8 bits; conditional E-value: 3.7e-124 Adaptin_N 3 ktiqqelaeilnsfkddprkkkeavkkllylimlGedvsflffevvklva.skdfelKrlvYlylkelaeesed.....laiLvtnslkkDlqspn 92 ++q+lae l++ dpr+k+ea+kk++++i++Ge++++l++ ++k+++ +d+++K+l+ +++++++++ +d ++iLv+++++kDlq+pn FUN_001184-T1 20 ALSEQKLAEDLEKG--DPRVKTEALKKVIQQILNGEKMPSLLMVIIKFLMpLDDHTIKKLLLIFWEIVPKTGKDgkllqEMILVCDAYRKDLQHPN 113 6789**********..******************************************************************************** PP Adaptin_N 93 qlirglALrtLskirspelaedlaraikkllvdrspyVrkkAalailklyrkspelvekfveelkell..sdkdpgVvsaAvalleeikkndklll 186 ++irg++Lr+L+k++++el+e l++ai+++l++r++yVr++A++ai+++yr+++ l+++ ++el++ + +++d +++++A+++l+++ d++ FUN_001184-T1 114 EYIRGSTLRFLCKLKEAELLEPLMPAIRNCLEHRHSYVRRNAVMAIYTIYRNFDFLIPD-APELVHTFleQEQDASCKRNAFMMLIHV---DQD-- 203 *********************************************************88.99999999899999**************...999.. PP Adaptin_N 187 kllpklvrrlknllgelnpwlqvkilrllsrlarqdpeeskkelledilnllqssnnaVlletvktivelasesellvlavnaLvrlls.ssdenl 281 ++l++l+++++++ +++ ++lq++i++l++++++++p+e+ ++++++i+nll+ss++aV +e++ t+v+l+s++++++ a++++++l+ +sd+n+ FUN_001184-T1 204 RALEYLSTCIDQV-NTFGDILQLVIVELIYKVCHANPAER-SRFIRCIYNLLNSSSPAVRYEAAGTLVTLSSAPTAVKSAASCYIELIVkESDNNV 297 99*********99.**************************.89**********************************************9****** PP Adaptin_N 282 ryvaLrtlnkiveke.pkavq.hkdlkleclktdddisirlralelllklvnesNvkeivkeLkkyvsevaded.......fkselvkaIgslaek 368 ++++L++l ++e+ +++v ++ +++ ++ +++d ++r+++l+l+l+lv+++N++e+v Lkk+v+++++e+ ++++lv++++++++k FUN_001184-T1 298 KLIVLDRLIALKENPsHEKVLrDLVMDILRVLSSPDLEVRKKTLQLVLDLVTSRNIHEVVAVLKKEVTKTHNESehediggYRQMLVRTLHTCSVK 393 *************977677777*********************************************66666666669****************** PP Adaptin_N 369 fatdaewvldvllellklageyvkdeiveviidiiqkvpelreyivekLcelletieseeakaaalWilGeygelisnte.sasdllrsilekfvl 463 f+++a ++++ l+e+l +++e ++ +++ ++++ +q++++l+ i ekL+e ++ti+ ++++ alWi+Gey++ +++ +++++ + + e+++ FUN_001184-T1 394 FPDVAVSIVPLLMEFLGDSNEQAAFDVLLFVREAVQRFEQLKPVIMEKLLENFHTIKTVKIHRHALWIMGEYATSKQDILdVMQEIKKGLGEVPIV 489 ******************************************************************************888888888999999999 PP Adaptin_N 464 esakvraa 471 ++ raa FUN_001184-T1 490 DDEMKRAA 497 99888877 PP >> Coatomer_b_Cpla Coatomer beta subunit appendage platform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 196.8 0.0 7.8e-62 1.5e-58 1 128 [] 821 951 .. 821 951 .. 0.96 Alignments for each domain: == domain 1 score: 196.8 bits; conditional E-value: 7.8e-62 Coatomer_b_Cpla 1 dravvilndikidimdyikpakiseeeFremWaefeWEnkitvktklsdlkeyleelvkktnmklltpeeeleeeaeflsanlyaksvfgedal 94 dr++v+lndi+idimdyi pa++++++Fr+mWaefeWEnk+tv+t++sdl+eyl++l+++tnmk+ltpe++l++e++f++anlya+s+fgedal FUN_001184-T1 821 DRNCVVLNDIHIDIMDYIVPATCTDSDFRQMWAEFEWENKVTVNTNISDLREYLNHLIASTNMKCLTPEKALAGECGFMAANLYARSIFGEDAL 914 799******************************************************************************************* PP Coatomer_b_Cpla 95 anvsiekee...egkisgvvRiRsktqgialslgdki 128 anvsiek + +++g+vRiR+k+qg+alslgdki FUN_001184-T1 915 ANVSIEKPSdqsGPSVTGHVRIRAKSQGMALSLGDKI 951 *******99433347********************98 PP >> Coatamer_beta_C Coatomer beta C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 188.9 0.3 2.5e-59 4.8e-56 1 136 [. 675 814 .. 675 815 .. 0.93 Alignments for each domain: == domain 1 score: 188.9 bits; conditional E-value: 2.5e-59 Coatamer_beta_C 1 vddlisfrqlkkkkeeeeeee.veedlska...tgakkkeeelssklkkivqLtGfsDpvYaEayvkvhqfDivldvllvNqtketlqnltvel 90 vdd+i f+ql +k+++ +e+ + ls+a +g+kk+ee + skl+k+ qLtGfsDpvYaEayv+v+q+Divld+l+vNqt++tlqn+t+el FUN_001184-T1 675 VDDPIPFMQLLAKSDSGITEDqFALALSQAvgsVGGKKEEELVGSKLNKVAQLTGFSDPVYAEAYVNVNQYDIVLDLLIVNQTSDTLQNVTLEL 768 69*******99888666555459999999977677788899999************************************************** PP Coatamer_beta_C 91 atlGdlklvekpqsvtlaphdfakikatvkvsstetGvifgnivYd 136 atlGdlklvekpq++ l+p+df++ika+vkvsste+G+ifgnivYd FUN_001184-T1 769 ATLGDLKLVEKPQPIMLGPNDFSNIKANVKVSSTENGIIFGNIVYD 814 *********************************************9 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 1.5 2.9e+03 9 27 .. 109 127 .. 102 129 .. 0.87 2 ! 14.9 0.0 1.7e-05 0.034 1 30 [. 136 165 .. 136 166 .. 0.94 3 ! 15.2 0.0 1.4e-05 0.027 2 29 .. 246 273 .. 245 274 .. 0.91 4 ? 5.1 0.1 0.026 50 5 28 .. 325 348 .. 322 350 .. 0.83 5 ? 1.0 0.0 0.54 1.1e+03 1 14 [. 401 414 .. 401 416 .. 0.91 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 1.5 HEAT 9 lnDpspeVReaAaeaLgal 27 l++p++ +R ++++ L++l FUN_001184-T1 109 LQHPNEYIRGSTLRFLCKL 127 89********999999876 PP == domain 2 score: 14.9 bits; conditional E-value: 1.7e-05 HEAT 1 llplllkllnDpspeVReaAaeaLgalaev 30 l+p++ ++l++ ++ VR++A+ a+++++++ FUN_001184-T1 136 LMPAIRNCLEHRHSYVRRNAVMAIYTIYRN 165 79************************9876 PP == domain 3 score: 15.2 bits; conditional E-value: 1.4e-05 HEAT 2 lplllkllnDpspeVReaAaeaLgalae 29 + ++ +lln++sp VR+ Aa +L++l++ FUN_001184-T1 246 IRCIYNLLNSSSPAVRYEAAGTLVTLSS 273 67999*******************9975 PP == domain 4 score: 5.1 bits; conditional E-value: 0.026 HEAT 5 llkllnDpspeVReaAaeaLgala 28 +l+ l++p+ eVR+ +++ + +l+ FUN_001184-T1 325 ILRVLSSPDLEVRKKTLQLVLDLV 348 46679***********99987776 PP == domain 5 score: 1.0 bits; conditional E-value: 0.54 HEAT 1 llplllkllnDpsp 14 ++pll++ l D+++ FUN_001184-T1 401 IVPLLMEFLGDSNE 414 89*********997 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2.4 4.8e+03 6 55 .. 13 66 .. 10 79 .. 0.53 2 ! 18.3 0.0 1.5e-06 0.0029 8 85 .. 109 195 .. 103 198 .. 0.77 3 ! 13.4 0.0 5.1e-05 0.1 4 72 .. 140 214 .. 138 218 .. 0.82 4 ! 8.7 0.0 0.0016 3.1 35 64 .. 248 278 .. 240 286 .. 0.79 5 ? 2.4 0.0 0.14 2.8e+02 7 51 .. 288 340 .. 285 369 .. 0.70 6 ? 0.1 0.0 0.71 1.4e+03 17 45 .. 380 414 .. 377 423 .. 0.71 7 ? -1.7 0.0 2.6 5.1e+03 28 58 .. 542 572 .. 530 575 .. 0.82 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2.4 HEAT_2 6 qaLlkdpdpevraaairaLg....eigdpealpaLlell.kdedpavRraaakaL 55 ++L +d++ + ++ L ++++++ ++++++l + + p + ++k L FUN_001184-T1 13 NVL-SDSEALSEQKLAEDLEkgdpRVKTEALKKVIQQILnGEKMPSLLMVIIKFL 66 555.555555555555555544445555555555555553344455555555555 PP == domain 2 score: 18.3 bits; conditional E-value: 1.5e-06 HEAT_2 8 LlkdpdpevraaairaLgeigdpea....lpaLlellkdedpavRraaakaLgkig.d.....pealpaLlelladddddvvraaaae 85 L ++p++++r +r L++++++e pa++++l++ ++ vRr+a++a+ i + p+a ++ l+ ++d+ +++ a + FUN_001184-T1 109 L-QHPNEYIRGSTLRFLCKLKEAELleplMPAIRNCLEHRHSYVRRNAVMAIYTIYrNfdfliPDAPELVHTFLEQEQDASCKRNAFM 195 6.89*******************994444556666668999***********988532446667777777778888877777777665 PP == domain 3 score: 13.4 bits; conditional E-value: 5.1e-05 HEAT_2 4 LlqaLlkdpdpevraaairaLg......eigd..pealpaLlell.kdedpavRraaakaLgkigdpealpaLlella 72 + + L ++ + +vr++a++a+ p+a ++++ +l + d +r+a ++L +++++al++L +++ FUN_001184-T1 140 IRNCL-EHRHSYVRRNAVMAIYtiyrnfD--FliPDAPELVHTFLeQEQDASCKRNAFMMLIHVDQDRALEYLSTCID 214 66778.999************97755333..2337999*******7788999*******************9988775 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0016 HEAT_2 35 aLlellkdedpavRraaakaLgkigd.peal 64 + +ll++++pavR++aa +L + + p+a+ FUN_001184-T1 248 CIYNLLNSSSPAVRYEAAGTLVTLSSaPTAV 278 6778999999999999999999887656665 PP == domain 5 score: 2.4 bits; conditional E-value: 0.14 HEAT_2 7 aLlkdpdpevraaai.raLgeigdp.......ealpaLlellkdedpavRraa 51 +++k++d +v+ ++ r ++ +p + + +l++l+++d +vR+ FUN_001184-T1 288 LIVKESDNNVKLIVLdRLIALKENPshekvlrDLVMDILRVLSSPDLEVRKKT 340 55667777777777744555444554445555778888899999999999875 PP == domain 6 score: 0.1 bits; conditional E-value: 0.71 HEAT_2 17 raaairaLg..eigdp....ealpaLlellkdedp 45 r++ +r+L ++ p +++p+L+e+l+d+++ FUN_001184-T1 380 RQMLVRTLHtcSVKFPdvavSIVPLLMEFLGDSNE 414 66667777755455553334559*******99986 PP == domain 7 score: -1.7 bits; conditional E-value: 2.6 HEAT_2 28 gdpealpaLlellkdedpavRraaakaLgki 58 +d+e +p+++++l d + v +a+a +L k+ FUN_001184-T1 542 KDEEKRPPMRQYLLDGEFFVGAAIACTLTKL 572 6788899999999999999999999888765 PP >> Cnd1 non-SMC mitotic condensation complex subunit 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 6.9 1.4e+04 25 48 .. 25 48 .. 22 69 .. 0.70 2 ! 25.6 0.1 7.8e-09 1.5e-05 2 52 .. 116 166 .. 115 226 .. 0.76 3 ! 10.6 1.5 0.00032 0.63 21 125 .. 244 350 .. 222 376 .. 0.77 4 ? 0.2 0.0 0.51 1e+03 3 35 .. 380 414 .. 378 416 .. 0.91 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 6.9 Cnd1 25 pLrkrLkDedpyVRktAaivvakL 48 +L + L+ dp V+ A+ v + FUN_001184-T1 25 KLAEDLEKGDPRVKTEALKKVIQQ 48 566677777777777777665554 PP == domain 2 score: 25.6 bits; conditional E-value: 7.8e-09 Cnd1 2 iRalairtlgcirvpnlveylvepLrkrLkDedpyVRktAaivvakLilnd 52 iR+ ++r l+ ++ +l+e+l++ +r++L+ ++ yVR++A++++ +++n FUN_001184-T1 116 IRGSTLRFLCKLKEAELLEPLMPAIRNCLEHRHSYVRRNAVMAIYTIYRNF 166 9*******************************************9997764 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00032 Cnd1 21 ylvepLrkrLkDedpyVRktAaivvakLilndmvkvkgflselaklLeDenprVvanalaalteisek..senaiynllpdiisklsdalnecsew 114 ++ +++ L+ ++p VR Aa +++ L ++ + ++ ++ +++++++V ++l l ++e+ +e+ + l+ di+ ls+ + e+ ++ FUN_001184-T1 244 RFIRCIYNLLNSSSPAVRYEAAGTLVTLSSAPTAVKSAASCYIELIVKESDNNVKLIVLDRLIALKENpsHEKVLRDLVMDILRVLSSPDLEVRKK 339 5677899*********************66655555566777888888888888888888887777776545888889999999999888888888 PP Cnd1 115 gqktileaLls 125 + + +l++++s FUN_001184-T1 340 TLQLVLDLVTS 350 88888887765 PP == domain 4 score: 0.2 bits; conditional E-value: 0.51 Cnd1 3 Ralairtlg..cirvpnlveylvepLrkrLkDedp 35 R +++rtl ++++p++ +v+ L + L D++ FUN_001184-T1 380 RQMLVRTLHtcSVKFPDVAVSIVPLLMEFLGDSNE 414 78999**98889******************99985 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 0.0001 0.2 15 54 .. 122 161 .. 117 162 .. 0.84 2 ! 10.3 0.0 0.0006 1.2 28 52 .. 244 268 .. 235 271 .. 0.87 3 ? 0.9 0.0 0.51 1e+03 26 50 .. 322 342 .. 311 344 .. 0.65 4 ? 2.5 0.0 0.17 3.3e+02 21 42 .. 393 414 .. 382 417 .. 0.81 5 ? -0.2 0.0 1.2 2.3e+03 4 23 .. 455 474 .. 452 478 .. 0.81 6 ? -3.1 0.0 9.6 1.9e+04 22 42 .. 827 847 .. 826 849 .. 0.82 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.0001 HEAT_EZ 15 aeggpdllapllpellplLlplLnddddeVReaAawaLgr 54 + ++ + a ll+ l+p+ ++ L++ ++ VR +A+ a+ FUN_001184-T1 122 RFLCKLKEAELLEPLMPAIRNCLEHRHSYVRRNAVMAIYT 161 55666666778899***********************976 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0006 HEAT_EZ 28 ellplLlplLnddddeVReaAawaL 52 + + + +lLn+++++VR+ Aa++L FUN_001184-T1 244 RFIRCIYNLLNSSSPAVRYEAAGTL 268 56788899***************99 PP == domain 3 score: 0.9 bits; conditional E-value: 0.51 HEAT_EZ 26 lpellplLlplLnddddeVReaAaw 50 + ++l L ++d eVR+++++ FUN_001184-T1 322 VMDILRVLS----SPDLEVRKKTLQ 342 445555555....5555****9975 PP == domain 4 score: 2.5 bits; conditional E-value: 0.17 HEAT_EZ 21 llapllpellplLlplLndddd 42 + ++++ ++plL+ +L d++ FUN_001184-T1 393 KFPDVAVSIVPLLMEFLGDSNE 414 55667779**********9986 PP == domain 5 score: -0.2 bits; conditional E-value: 1.2 HEAT_EZ 4 ReaAalaLGslaeggpdlla 23 ++A++ +G+ a + d+l+ FUN_001184-T1 455 HRHALWIMGEYATSKQDILD 474 689*******9988887775 PP == domain 6 score: -3.1 bits; conditional E-value: 9.6 HEAT_EZ 22 lapllpellplLlplLndddd 42 l++ + +++++ +p+ ++d+d FUN_001184-T1 827 LNDIHIDIMDYIVPATCTDSD 847 66777899*****99998886 PP >> TPR_Trm732_C Trm732, C-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.8 0.0 0.0083 16 91 126 .. 129 164 .. 119 193 .. 0.81 2 ! 6.6 0.1 0.0047 9.3 91 137 .. 238 284 .. 219 298 .. 0.77 3 ! 9.6 0.3 0.00054 1.1 74 148 .. 299 370 .. 290 378 .. 0.80 4 ? 0.6 0.0 0.33 6.4e+02 35 62 .. 424 451 .. 405 465 .. 0.80 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0083 TPR_Trm732_C 91 eaeslsefvplvlkclaskiwkvRemaAralvalvs 126 eae l++++p +++cl+++ vR a a+ ++ FUN_001184-T1 129 EAELLEPLMPAIRNCLEHRHSYVRRNAVMAIYTIYR 164 567799**********************99988765 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0047 TPR_Trm732_C 91 eaeslsefvplvlkclaskiwkvRemaAralvalvsssevlslllsl 137 + + s+f+ + ++l+s+ vR aA +lv+l s+ ++++ ++s FUN_001184-T1 238 NPAERSRFIRCIYNLLNSSSPAVRYEAAGTLVTLSSAPTAVKSAASC 284 4556799***************************9998887766554 PP == domain 3 score: 9.6 bits; conditional E-value: 0.00054 TPR_Trm732_C 74 LllLsrLqpsspeeeeseaeslsefvplvlkclaskiwkvRemaAralvalvsssevlslllsllkslsslsqNe 148 L +L rL + + e+ s+ + l+++v +l++l+s+ ++vR+ + + + lv+s+++ ++++ l k+ ++++Ne FUN_001184-T1 299 LIVLDRLIALK--ENPSHEKVLRDLVMDILRVLSSPDLEVRKKTLQLVLDLVTSRNIHEVVAVL-KKEVTKTHNE 370 78999997665..455666799********************************9988876654.4444445554 PP == domain 4 score: 0.6 bits; conditional E-value: 0.33 TPR_Trm732_C 35 greFFsrypsLrpfLleeLeeaveslss 62 +re +r+++L+p+++e+L e ++++ FUN_001184-T1 424 VREAVQRFEQLKPVIMEKLLENFHTIKT 451 677889*************887776654 PP >> Coatomer_g_Cpla Coatomer subunit gamma-1 C-terminal appendage platform # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 2.1e-07 0.00041 2 108 .. 836 944 .. 835 951 .. 0.87 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 2.1e-07 Coatomer_g_Cpla 2 Dyiqpvevs..nFksaWdeleseaeesetfalssvksleeavekliellglqplegsdkvpenassHtlkLsGklvggekvlvrarlalsssk. 92 Dyi p+ + +F+++W e e e++ t++ ++++l+e ++li +++++ l + + + +L++ ++ ge+ l+++++ + s++ FUN_001184-T1 836 DYIVPATCTdsDFRQMWAEFEW--ENKVTVNT-NISDLREYLNHLIASTNMKCLTPEKALAGECGFMAANLYARSIFGEDALANVSIEKPSDQs 926 99999998888***********..45455555.7799*********************99999999*********************9987542 PP Coatomer_g_Cpla 93 ..gvtlkltvRseseevs 108 +vt ++ +R++s+ ++ FUN_001184-T1 927 gpSVTGHVRIRAKSQGMA 944 237**********99876 PP >> Arm Armadillo/beta-catenin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.038 75 13 33 .. 136 156 .. 130 161 .. 0.89 2 ! 9.4 0.0 0.00079 1.6 14 40 .. 246 272 .. 242 273 .. 0.87 3 ? -0.9 0.0 1.4 2.8e+03 18 30 .. 326 338 .. 325 341 .. 0.85 4 ? -0.7 0.0 1.2 2.4e+03 13 27 .. 401 415 .. 397 421 .. 0.81 5 ? -3.1 0.0 7 1.4e+04 16 30 .. 680 694 .. 680 695 .. 0.84 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.038 Arm 13 avppLvrLLsspdeevqeeAa 33 +p+ ++L++ ++ v+++A+ FUN_001184-T1 136 LMPAIRNCLEHRHSYVRRNAV 156 589*****************8 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00079 Arm 14 vppLvrLLsspdeevqeeAawALsNLa 40 ++ +LL+s+++ v+ eAa++L L+ FUN_001184-T1 246 IRCIYNLLNSSSPAVRYEAAGTLVTLS 272 566779*****************8887 PP == domain 3 score: -0.9 bits; conditional E-value: 1.4 Arm 18 vrLLsspdeevqe 30 +r Lsspd ev++ FUN_001184-T1 326 LRVLSSPDLEVRK 338 678********98 PP == domain 4 score: -0.7 bits; conditional E-value: 1.2 Arm 13 avppLvrLLsspdee 27 +vp L+++L +++e+ FUN_001184-T1 401 IVPLLMEFLGDSNEQ 415 8********987775 PP == domain 5 score: -3.1 bits; conditional E-value: 7 Arm 16 pLvrLLsspdeevqe 30 p+++LL +d+ + e FUN_001184-T1 680 PFMQLLAKSDSGITE 694 799****99998876 PP >> TOR1L1_N TORTIFOLIA1 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.36 7e+02 206 240 .. 130 164 .. 119 185 .. 0.77 2 ! 8.5 0.0 0.00083 1.6 192 244 .. 225 277 .. 204 295 .. 0.84 3 ! 5.4 0.4 0.0069 13 75 215 .. 313 445 .. 295 453 .. 0.72 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.36 TOR1L1_N 206 kqslssllqsivefLkseDWatRKaAaeaLaklav 240 + l+ l++ i ++L+++ +R+ A+ a+ + FUN_001184-T1 130 AELLEPLMPAIRNCLEHRHSYVRRNAVMAIYTIYR 164 45688999999999999999999999999988755 PP == domain 2 score: 8.5 bits; conditional E-value: 0.00083 TOR1L1_N 192 leligsliqvgaiskqslssllqsivefLkseDWatRKaAaeaLaklavseke 244 l +++ + +v +++ + s ++++i + L+s+ a+R Aa +L l+++ + FUN_001184-T1 225 LVIVELIYKVCHANPAERSRFIRCIYNLLNSSSPAVRYEAAGTLVTLSSAPTA 277 567788889999999999**************************999887554 PP == domain 3 score: 5.4 bits; conditional E-value: 0.0069 TOR1L1_N 75 llsphlskiiasivrrlkDsDssVrdAcvdavgslaskllkkeeegeekessvvsllvkPLfealgeqnknvqaGaalcLaavieaakdpevaalq 170 + + l ++ i+r l +D +Vr+ + v l+++ ++vv++l k +++ +e +++ G + L + +++++ + + + FUN_001184-T1 313 SHEKVLRDLVMDILRVLSSPDLEVRKKTLQLVLDLVTSRN---------IHEVVAVLKKEVTKTHNESEHEDIGGYRQMLVRTLHTCSVKFPDVAV 399 4455677788888888888888888888887777766532.........23577888888888888888888888888888888888888888888 PP TOR1L1_N 171 kllprlvkllksesfkakaalleligsliqv.gaiskqslssllqs 215 ++p l+ +l ++ +a +l +++ +q +++++ +++ll+ FUN_001184-T1 400 SIVPLLMEFLGDSNEQAAFDVLLFVREAVQRfEQLKPVIMEKLLEN 445 8888888888888888888888888877775256677777777665 PP >> MMS19_N Dos2-interacting transcription regulator of RNA-Pol-II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.048 95 122 149 .. 38 66 .. 7 84 .. 0.71 2 ? -1.2 0.0 0.87 1.7e+03 82 111 .. 301 330 .. 229 368 .. 0.48 3 ! 11.5 0.0 0.00012 0.23 182 242 .. 373 433 .. 364 455 .. 0.85 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.048 MMS19_N 122 gedflkgfi.elidgEkDPrnLllvFsll 149 +++ lk +i ++++gEk P L+++ ++l FUN_001184-T1 38 KTEALKKVIqQILNGEKMPSLLMVIIKFL 66 3366666662578***********99876 PP == domain 2 score: -1.2 bits; conditional E-value: 0.87 MMS19_N 82 vlkslfqevqvqsllqseRylvfqlldtll 111 vl+ l+ + +s+ + R lv+++l+ l FUN_001184-T1 301 VLDRLIALKENPSHEKVLRDLVMDILRVLS 330 333333333333333333444444443333 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00012 MMS19_N 182 ndpykItredLkeaLreclaatplfaefaipllleKLsssspsaklDsLktLkacvekyga 242 +++++ r+ L ++L c + p+ a ++pll+e L +s+++a D+L ++++v+++++ FUN_001184-T1 373 HEDIGGYRQMLVRTLHTCSVKFPDVAVSIVPLLMEFLGDSNEQAAFDVLLFVREAVQRFEQ 433 5556667999*************************************************65 PP >> INTS1_R4 Integrator complex subunit 1, R4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.18 3.5e+02 66 91 .. 131 156 .. 90 165 .. 0.63 2 ? 5.6 0.0 0.011 21 55 93 .. 229 267 .. 224 273 .. 0.91 3 ? 6.1 0.2 0.0074 15 26 63 .. 313 350 .. 293 361 .. 0.88 4 ? -0.3 0.0 0.74 1.4e+03 8 22 .. 467 481 .. 464 487 .. 0.86 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.18 INTS1_R4 66 seaekvlsaflqCLdsedsdvvqtal 91 + e +++a +CL++++s v + a+ FUN_001184-T1 131 ELLEPLMPAIRNCLEHRHSYVRRNAV 156 34445566666666666666666554 PP == domain 2 score: 5.6 bits; conditional E-value: 0.011 INTS1_R4 55 sLvlrllrknPseaekvlsaflqCLdsedsdvvqtalkn 93 +L+ ++ + nP+e ++++ + + L+s+ ++v a FUN_001184-T1 229 ELIYKVCHANPAERSRFIRCIYNLLNSSSPAVRYEAAGT 267 6999****************************9888765 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0074 INTS1_R4 26 rkpevLehfvdelkellvssneevRelAfsLvlrllrk 63 ++ +vL+ +v ++ ++l+s++ evR+ +Lvl l+ + FUN_001184-T1 313 SHEKVLRDLVMDILRVLSSPDLEVRKKTLQLVLDLVTS 350 56789***************************988765 PP == domain 4 score: -0.3 bits; conditional E-value: 0.74 INTS1_R4 8 eqsedvlevLqelde 22 ++++d+l+v+qe+++ FUN_001184-T1 467 TSKQDILDVMQEIKK 481 6789********986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (960 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 992 (0.0388334); expected 510.9 (0.02) Passed bias filter: 750 (0.02936); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.44u 0.40s 00:00:00.84 Elapsed: 00:00:00.43 # Mc/sec: 9061.38 // Query: FUN_001185-T1 [L=910] Description: FUN_001185 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-79 260.8 145.6 1.4e-13 51.3 10.4 8.5 7 Ldl_recept_a Low-density lipoprotein receptor domain class 1e-33 116.0 7.7 2.1e-12 47.8 0.1 5.6 5 Ldl_recept_b Low-density lipoprotein receptor repeat class 2.8e-17 63.0 38.9 8.8e-09 35.9 7.5 7.4 4 FXa_inhibition Coagulation Factor Xa inhibitory site 1.3e-14 54.1 21.5 2e-10 40.8 1.0 5.3 4 cEGF Complement Clr-like EGF-like 2e-08 34.8 23.9 2.2e-07 31.5 7.1 10.5 3 EGF_CA Calcium-binding EGF domain 0.00016 22.5 1.4 0.00035 21.4 1.4 1.6 1 Podoplanin Podoplanin 0.00017 22.3 9.4 0.00036 21.2 9.4 1.5 1 PARM PARM 0.0017 18.9 5.9 0.0017 18.9 5.9 5.7 5 Plasmod_Pvs28 Pvs28 EGF domain 0.003 17.7 0.5 0.03 14.4 0.5 3.0 1 SGL SMP-30/Gluconolactonase/LRE-like region ------ inclusion threshold ------ 0.19 12.5 0.0 0.88 10.3 0.0 2.2 2 Arylesterase Arylesterase 0.24 11.4 0.0 0.4 10.7 0.0 1.2 1 RTA1 RTA1 like protein 1.3 9.9 10.2 9.1 7.2 10.2 2.2 1 DUF1180 Membrane protein FAM174-like 4.2 7.1 9.5 6.6 6.4 9.5 1.2 1 Med13_C Mediator complex subunit 13 C-terminal domain Domain annotation for each model (and alignments): >> Ldl_recept_a Low-density lipoprotein receptor domain class A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.3 13.2 9.1e-14 1.8e-10 2 37 .] 30 65 .. 29 65 .. 0.98 2 ! 38.8 11.6 5.8e-13 1.1e-09 1 37 [] 68 104 .. 68 104 .. 0.98 3 ! 46.7 12.8 1.9e-15 3.7e-12 2 37 .] 109 144 .. 108 144 .. 0.98 4 ! 40.3 14.7 2e-13 3.9e-10 2 37 .] 148 185 .. 147 185 .. 0.94 5 ! 51.3 10.4 7.2e-17 1.4e-13 2 37 .] 189 224 .. 188 224 .. 0.99 6 ! 46.7 15.7 1.9e-15 3.7e-12 3 37 .] 235 269 .. 233 269 .. 0.98 7 ! 42.2 9.1 4.8e-14 9.4e-11 1 37 [] 270 308 .. 270 308 .. 0.97 Alignments for each domain: == domain 1 score: 41.3 bits; conditional E-value: 9.1e-14 Ldl_recept_a 2 tCepnefqCgsgeCIprswvCdgeaDCeDgSDEenC 37 C+ +f Cgs++CIp +w+Cd+ +DC D+SDE++C FUN_001185-T1 30 HCGDGKFACGSRKCIPDRWRCDDYDDCGDQSDEVGC 65 5**********************************9 PP == domain 2 score: 38.8 bits; conditional E-value: 5.8e-13 Ldl_recept_a 1 ktCepnefqCgsgeCIprswvCdgeaDCeDgSDEenC 37 ktC + f+C++g+C+ +s+vCd ++DC DgSDE++C FUN_001185-T1 68 KTCLDHRFNCTNGRCVWKSFVCDFDDDCGDGSDEVGC 104 69**********************************9 PP == domain 3 score: 46.7 bits; conditional E-value: 1.9e-15 Ldl_recept_a 2 tCepnefqCgsgeCIprswvCdgeaDCeDgSDEenC 37 tC n+f+C+sg+CI+ w+Cdge+DC D+SDE +C FUN_001185-T1 109 TCPDNKFKCKSGKCIDILWKCDGENDCLDNSDETSC 144 9*********************************99 PP == domain 4 score: 40.3 bits; conditional E-value: 2e-13 Ldl_recept_a 2 tCepnefqCgsgeCIprswvCdgeaDCeDgSDE..enC 37 tC +n+f C++++C+prs Cdg++DCeD+SDE +C FUN_001185-T1 148 TCPSNKFTCNNNNCVPRSHLCDGDDDCEDNSDEttDQC 185 9********************************77777 PP == domain 5 score: 51.3 bits; conditional E-value: 7.2e-17 Ldl_recept_a 2 tCepnefqCgsgeCIprswvCdgeaDCeDgSDEenC 37 tC++n+f C + CIp++w+Cdg+aDC+DgSDE++C FUN_001185-T1 189 TCSSNQFTCPNHMCIPSRWRCDGDADCSDGSDEKGC 224 8*********************************** PP == domain 6 score: 46.7 bits; conditional E-value: 1.9e-15 Ldl_recept_a 3 CepnefqCgsgeCIprswvCdgeaDCeDgSDEenC 37 C ++ f+C++g+CI +sw+Cdge+DC+DgSDEe+C FUN_001185-T1 235 CAEQMFSCNDGNCIRNSWRCDGENDCQDGSDEERC 269 99********************************* PP == domain 7 score: 42.2 bits; conditional E-value: 4.8e-14 Ldl_recept_a 1 ktCepnefqCgsge.CIprswvCdgeaDCeDgSDE.enC 37 +tC++++f+Cg+++ CIp+s +C+g++DC +g+DE nC FUN_001185-T1 270 STCSSDKFKCGNTSlCIPQSQRCNGKRDCPNGEDEpLNC 308 59*********************************9999 PP >> Ldl_recept_b Low-density lipoprotein receptor repeat class B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.0 4.2e-05 0.082 1 42 [] 437 482 .. 437 482 .. 0.82 2 ! 47.8 0.1 1.1e-15 2.1e-12 2 42 .] 486 525 .. 485 525 .. 0.98 3 ! 36.2 0.1 4.6e-12 9e-09 1 42 [] 528 572 .. 528 572 .. 0.90 4 ! 16.1 0.0 8.4e-06 0.017 1 27 [. 575 600 .. 575 602 .. 0.94 5 ? 2.1 0.1 0.19 3.8e+02 1 25 [. 616 642 .. 616 647 .. 0.76 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 4.2e-05 Ldl_recept_b 1 grlYWtDwslrasissadlnGsdrktllted.......lqhPnaIavDh 42 ++l+WtD + + +i a+l +d t+ + +++P++IavD+ FUN_001185-T1 437 NYLFWTDIRDE-RICGARLPSQD--TTAALCertvvssVSSPEGIAVDW 482 79*********.88888887666..6666666677777**********9 PP == domain 2 score: 47.8 bits; conditional E-value: 1.1e-15 Ldl_recept_b 2 rlYWtDwslrasissadlnGsdrktlltedlqhPnaIavDh 42 ++YWtD++ +i +a ++Gs+r+tl+ +d+++P+aI+vD+ FUN_001185-T1 486 KIYWTDGGHN-VIEVAEFDGSHRLTLFYNDIYDPRAIVVDP 525 9*********.*****************************7 PP == domain 3 score: 36.2 bits; conditional E-value: 4.6e-12 Ldl_recept_b 1 grlYWtDwslr.asissadlnGsd.rktllted.lqhPnaIavDh 42 g+l+WtDw + ++i +++++G + +t++ ++ l +Pna+a+D+ FUN_001185-T1 528 GYLFWTDWFTNsPRIERSGMDGNPsTRTVVVSErLGWPNALAIDY 572 79***********************666666666**********8 PP == domain 4 score: 16.1 bits; conditional E-value: 8.4e-06 Ldl_recept_b 1 grlYWtDwslrasissadlnGsdrktl 27 +r++W D++l+ ++ s++ +G+dr+++ FUN_001185-T1 575 QRIFWADAKLK-TVESSTYDGTDRRVI 600 69*********.************998 PP == domain 5 score: 2.1 bits; conditional E-value: 0.19 Ldl_recept_b 1 grlYWtDwslr..asissadlnGsdrk 25 ++lY tDw + s++++nGsd++ FUN_001185-T1 616 NHLYYTDWYRFdrGIRSMNKFNGSDEH 642 689999997655567789999999855 PP >> FXa_inhibition Coagulation Factor Xa inhibitory site # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.9 4.5 8.8e+03 5 13 .. 101 111 .. 98 118 .. 0.76 2 ! 35.9 7.5 4.5e-12 8.8e-09 1 36 [] 313 348 .. 313 348 .. 0.99 3 ! 22.8 6.6 5.3e-08 0.0001 6 36 .] 358 388 .. 354 388 .. 0.94 4 ! 34.2 8.8 1.5e-11 2.9e-08 1 36 [] 670 707 .. 670 707 .. 0.96 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 4.5 FXa_inhibition 5 NggCs..hlCl 13 gC+ h+C FUN_001185-T1 101 EVGCDrnHTCP 111 56898889995 PP == domain 2 score: 35.9 bits; conditional E-value: 4.5e-12 FXa_inhibition 1 CsvnNggCshlClntpggytCsCpeGyeLsdDgktC 36 C++ Ng+C++ C++ g++CsC++G++L++D+ktC FUN_001185-T1 313 CEYFNGHCQQVCTDLKVGFECSCHPGFKLANDQKTC 348 9999******************************** PP == domain 3 score: 22.8 bits; conditional E-value: 5.3e-08 FXa_inhibition 6 ggCshlClntpggytCsCpeGyeLsdDgktC 36 g+Cs+ C+n g+++CsC +Gy+L++++ C FUN_001185-T1 358 GQCSQDCINMKGTFECSCKPGYHLDANKMLC 388 89***********************999877 PP == domain 4 score: 34.2 bits; conditional E-value: 1.5e-11 FXa_inhibition 1 CsvnNggCshlClnt..pggytCsCpeGyeLsdDgktC 36 C+vnNg CshlCl p g++C+Cp+G+++++ + tC FUN_001185-T1 670 CEVNNGNCSHLCLLAvaPMGRSCRCPNGMQMQSGNGTC 707 *************887888**************999*9 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 5.4 1.1e+04 18 22 .. 121 125 .. 119 125 .. 0.84 2 ! 40.8 1.0 1e-13 2e-10 1 24 [] 330 353 .. 330 353 .. 0.97 3 ! 17.3 0.5 2.3e-06 0.0046 2 19 .. 371 388 .. 370 389 .. 0.89 4 ! 6.9 2.5 0.0041 8 3 20 .. 691 708 .. 689 708 .. 0.88 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 5.4 cEGF 18 tCvDI 22 +C+DI FUN_001185-T1 121 KCIDI 125 7***9 PP == domain 2 score: 40.8 bits; conditional E-value: 1e-13 cEGF 1 SYtCsCppGYtLagDGrtCvDIDE 24 ++ CsC+pG++La D++tC+DIDE FUN_001185-T1 330 GFECSCHPGFKLANDQKTCEDIDE 353 699********************9 PP == domain 3 score: 17.3 bits; conditional E-value: 2.3e-06 cEGF 2 YtCsCppGYtLagDGrtC 19 + CsC+pGY L+++ C FUN_001185-T1 371 FECSCKPGYHLDANKMLC 388 89**********998777 PP == domain 4 score: 6.9 bits; conditional E-value: 0.0041 cEGF 3 tCsCppGYtLagDGrtCv 20 C Cp+G + ++ + tC+ FUN_001185-T1 691 SCRCPNGMQMQSGNGTCT 708 6********998778**7 PP >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 8.8 1.5e-06 0.0029 2 43 .] 310 348 .. 309 348 .. 0.95 2 ! 31.5 7.1 1.1e-10 2.2e-07 1 40 [. 350 385 .. 350 388 .. 0.87 3 ? -1.8 5.0 2.7 5.4e+03 27 43 .] 691 707 .. 667 707 .. 0.87 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.5e-06 EGF_CA 2 vdECaegthnCpdentvCvNteGsfeCvCeegyennedgkkC 43 ++EC+ + +C ++vC+ + +feC+C++g++ +d+k+C FUN_001185-T1 310 INECEYFNGHC---QQVCTDLKVGFECSCHPGFKLANDQKTC 348 8**********...79******************99999999 PP == domain 2 score: 31.5 bits; conditional E-value: 1.1e-10 EGF_CA 1 DvdECaegthnCpdentvCvNteGsfeCvCeegyennedg 40 D+dEC+ +C ++ C+N +G+feC+C++gy+ ++++ FUN_001185-T1 350 DIDECEVFG-QC---SQDCINMKGTFECSCKPGYHLDANK 385 9******99.9*...79*****************955444 PP == domain 3 score: -1.8 bits; conditional E-value: 2.7 EGF_CA 27 eCvCeegyennedgkkC 43 +C+C++g + + + +C FUN_001185-T1 691 SCRCPNGMQMQSGNGTC 707 7********99999888 PP >> Podoplanin Podoplanin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 1.4 1.8e-07 0.00035 10 129 .. 734 865 .. 725 870 .. 0.58 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 1.8e-07 Podoplanin 10 vedgkvtpGvE..DkvvttgaseepsessglttlvptstesvtdkklEdlptsestvhakeesqsttt.pnvatsh........srekvgee.... 90 + + +tp D+v+t++ s++p +++ ++++ + +k p ++ ++++ ++ s+t+ + at + + e FUN_001185-T1 734 STAEPTTPTSKplDSVTTSSPSKAPGSKTEQGKDESKNVSTASPTKPSTKPSRARSNESLRKTTSPTAsGKTATKEdsnstqrhE------Epiiv 823 4444444444333999999999999775555555555555555555555555555555555555555534556665665443321......23333 PP Podoplanin 91 ...tqttvekdGLatvtLvGiivGvLl.aigfiGGiiivvvrk 129 ++ ++ GL+ ++++Gi+v ++ ++ +iG i +++ r+ FUN_001185-T1 824 sakRKDNSKHRGLPSGAIIGIVVAIVFfTVFVIGTIWFML-RR 865 33266677778************97661555555555554.44 PP >> PARM PARM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 9.4 1.8e-07 0.00036 118 274 .. 708 870 .. 659 872 .. 0.73 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 1.8e-07 PARM 118 asvpatgsqspaesptltSpqapasspsslstsppevssasvstnessaetstk.ptgapttpespteehssgetptshatsepvpeettsqetvp 212 + +p g p s+t+ Spq+ + ++++ +t+p+ + sv+t++ s++ +k ++g ++++++ t+ + t+ s+a s+ ++tts ++ FUN_001185-T1 708 TGTPINGPVGPNISATTPSPQSTTKASTAEPTTPTSKPLDSVTTSSPSKAPGSKtEQGKDESKNVSTASPTKPSTKPSRARSNESLRKTTSPTASG 803 666777777788899999999999999999999888888899888777665555277788899999999998888888888888888888888888 PP PARM 213 skvtcelvdtestttsprvim.....qeVehALSsGSiaAiTvtViAVVlLVFGvAAyLKiRHSSYG 274 +++t e +++ + p ++ + + L sG+i+ i v+++ + V G ++ R SYG FUN_001185-T1 804 KTATKEDSNSTQRHEEPIIVSakrkdNSKHRGLPSGAIIGIVVAIVFFTVFVIGTIWFMLRRTKSYG 870 77777555544444445444322221224568***************************99*****9 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 3.9 5.6 1.1e+04 4 15 .. 113 124 .. 104 133 .. 0.80 2 ? -3.4 2.0 7.7 1.5e+04 2 14 .. 272 286 .. 260 291 .. 0.74 3 ! 6.1 5.1 0.0086 17 12 41 .] 323 349 .. 313 349 .. 0.85 4 ! 18.9 5.9 8.6e-07 0.0017 7 40 .. 354 388 .. 353 389 .. 0.88 5 ? -3.1 1.1 6.4 1.3e+04 26 36 .. 692 701 .. 691 710 .. 0.60 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 5.6 Plasmod_Pvs28 4 l..KaCgengkCkl 15 + K C+ +gkC+ FUN_001185-T1 113 NkfK-CK-SGKCID 124 1557.99.999996 PP == domain 2 score: -3.4 bits; conditional E-value: 7.7 Plasmod_Pvs28 2 Cql...KaCgengkCk 14 C+ K Cg C+ FUN_001185-T1 272 CSSdkfK-CGNTSLCI 286 4446667.88888887 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0086 Plasmod_Pvs28 12 kCklglpqnsnhykCsCniGyv.llnenkCt 41 +C+ ++CsC +G++ +++++C+ FUN_001185-T1 323 VCTDL----KVGFECSCHPGFKlANDQKTCE 349 56666....6679*********99******6 PP == domain 4 score: 18.9 bits; conditional E-value: 8.6e-07 Plasmod_Pvs28 7 CgengkCklglpqnsnhykCsCniGyv.llnenkC 40 C ++g+C + +++ ++++CsC++Gy + n++ C FUN_001185-T1 354 CEVFGQCSQDCINMKGTFECSCKPGYHlDANKMLC 388 ***************************66666655 PP == domain 5 score: -3.1 bits; conditional E-value: 6.4 Plasmod_Pvs28 26 CsCniGyvlln 36 C C +G ++ FUN_001185-T1 692 CRCPNGMQ-MQ 701 88888877.33 PP >> SGL SMP-30/Gluconolactonase/LRE-like region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.5 1.5e-05 0.03 7 176 .. 432 600 .. 429 612 .. 0.73 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1.5e-05 SGL 7 wdeeegaLywvDilgqklhrldpatgeeevldlpervgalalradgglivalksgvalldldsgeltkladseedekpenrfND......gkvdpd 96 +d +e++L+w+Di+ ++++ ++ +++++ + + v + + ++g + ++++++++d ++ ++a+ + + ++ ND +vdp FUN_001185-T1 432 YDYRENYLFWTDIRDERICGARLPSQDTTAALCERTVVSSVSSPEGIAVDWATKKIYWTD-GGHNVIEVAEFDGSHRLTLFYNDiydpraIVVDPF 526 7889*******************9999999666665555555344444444444444444.3335555555544443445556633333369***9 PP SGL 97 GrlwaGtmaddeakgkeegalyrldpdgklerlldgltisNGlawspDgktlYlaDslarkiyafdydaeggelsnrrvf 176 + + t ++++++ e + + +p+++++++ ++l+ +N+la++ +++++aD +++ + yd ++ rv+ FUN_001185-T1 527 HGYLFWTDWFTNSPRIE-RSGMDGNPSTRTVVVSERLGWPNALAIDYTLQRIFWADAKLKTVESSTYDGTDR-----RVI 600 88888888998888885.7778999999***************************************85554.....444 PP >> Arylesterase Arylesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 9.9 1.9e+04 60 78 .. 431 449 .. 420 450 .. 0.76 2 ? 10.3 0.0 0.00045 0.88 47 75 .. 466 494 .. 464 503 .. 0.86 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 9.9 Arylesterase 60 nidadkkyiyvadilresi 78 +d + y++ +di +e i FUN_001185-T1 431 DYDYRENYLFWTDIRDERI 449 5899999999999988876 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00045 Arylesterase 47 kvvasglssanGInidadkkyiyvadilr 75 ++v+s++ss+ GI +d k iy +d + FUN_001185-T1 466 RTVVSSVSSPEGIAVDWATKKIYWTDGGH 494 6899*******************998655 PP >> RTA1 RTA1 like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.00021 0.4 107 134 .. 840 872 .. 822 898 .. 0.73 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00021 RTA1 107 iiaGlalQvvvlvvFlllaldfllrvr.....k 134 +i+G+++ +v+++vF++ +++f+lr + k FUN_001185-T1 840 AIIGIVVAIVFFTVFVIGTIWFMLRRTksyggK 872 689*********************988555551 PP >> DUF1180 Membrane protein FAM174-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 10.2 0.0046 9.1 30 163 .. 737 901 .. 718 905 .. 0.57 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0046 DUF1180 30 asqpeaepPlppgataaespgkataleaasaraa.eggngss.....pragsaad..............................aggslavvpel 89 ++++ +++Pl +++ sp ka+ +++++++ e++n s+ p +++++ p + FUN_001185-T1 737 EPTTPTSKPLDS--VTTSSPSKAPG--SKTEQGKdESKNVSTasptkP------StkpsrarsneslrkttsptasgktatkedsNSTQRHEEPII 822 444444445533..33334555555..222233202223333222221......122333344444555555554444444555567777777777 PP DUF1180 90 sspedkpmt.qral....ivlvvvsaavivylvvRtvrmrrrnrktRrYgvldtnienmElt..PLeqd.DedddntlFdan 163 s ++k ++ +r l i+ +vv+ + ++v+ t+ +r+t+ Yg +t + + t PL +d D+d+ Fd + FUN_001185-T1 823 VSAKRKDNSkHRGLpsgaIIGIVVAIVFFTVFVIGTIWF--MLRRTKSYGG-KTIVYHKDATtkPLAEDfDNDESFRAFDDK 901 7777777776777655536667777777899*****998..8999****98.665555544445*********999999876 PP >> Med13_C Mediator complex subunit 13 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 9.5 0.0033 6.6 131 258 .. 678 815 .. 645 826 .. 0.60 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0033 Med13_C 131 lsltLvsvepdpsLrlmppavtpdsafgssssstpvstP..qdssathilvfspsatgqatptssasepenaett......psdsspepdsdallv 218 +l+L++v p p+ ++++s g + + tp + P + sat+ s++++++a pt+ +s+p ++ tt p ++++++++++ v FUN_001185-T1 678 SHLCLLAVAPMGRSCRCPNGMQMQSGNG-TCTGTPINGPvgPNISATTPSPQSTTKASTAEPTTPTSKPLDSVTTsspskaPGSKTEQGKDESKNV 772 5777777777777666665555544444.5557777776332223332222233333344444444444444443444433344444447777777 PP Med13_C 219 dvtdetwgvilshrlnnsasltelqpplasGylvkrk...gta 258 + t++++ ++r +++sl ++ p asG +++ +t+ FUN_001185-T1 773 STASPTKPSTKPSRARSNESLRKTTSPTASGKTATKEdsnSTQ 815 777788888888999999999999*******888555354333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (910 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1615 (0.0632218); expected 510.9 (0.02) Passed bias filter: 674 (0.0263848); expected 510.9 (0.02) Passed Vit filter: 103 (0.0040321); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.45u 0.46s 00:00:00.91 Elapsed: 00:00:00.44 # Mc/sec: 8412.82 // Query: FUN_001186-T1 [L=274] Description: FUN_001186 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (274 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 661 (0.0258759); expected 510.9 (0.02) Passed bias filter: 462 (0.0180857); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2740.94 // Query: FUN_001188-T1 [L=304] Description: FUN_001188 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.7 0.7 0.28 11.7 0.2 1.7 2 PBP_N Penicillin-binding protein N-terminus 4.6 8.2 7.4 32 5.5 0.2 3.0 2 zf-TAZ TAZ zinc finger Domain annotation for each model (and alignments): >> PBP_N Penicillin-binding protein N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 0.5 6.4e+03 47 60 .. 16 28 .. 12 39 .. 0.65 2 ? 11.7 0.2 2.2e-05 0.28 33 115 .. 193 278 .. 173 286 .. 0.68 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 0.5 PBP_N 47 lssdaatpppppep 60 l+s a t pp pe FUN_001188-T1 16 LAS-AQTSPPNPEC 28 444.5566666665 PP == domain 2 score: 11.7 bits; conditional E-value: 2.2e-05 PBP_N 33 sqdpwa.pqgpd..pfrlssdaatpppppepppeepfradlkhaaakkkark..wgwvwgtllvgfllavlsvagggayvwfkylkdt 115 s w+ p+ p+r ss p p + p +p+ + k ++ g + g g++ +l v g+a w ky + t FUN_001188-T1 193 SSSRWSvPRTGPpfPLRSSSSGPYPHYPGNGPSSDPYAQGYSREDKDKSSKDlsTGAIIGICAAGLF-VILIVI-GAAVYWKKYHRRT 278 55566435554401556666666667799999*****998887766665554226888888887754.455555.5566699998876 PP >> zf-TAZ TAZ zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 2.3 0.0092 1.2e+02 25 52 .. 25 66 .. 8 86 .. 0.67 2 ? 5.5 0.2 0.0025 32 21 42 .. 162 183 .. 139 194 .. 0.80 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.0092 zf-TAZ 25 lkkCkkvkkllkHvksCk..............kkeCkvklCk 52 +++C+ + + +H+++ +k+C+ +Ck FUN_001188-T1 25 NPECRGMNTAARHLQTGIksipgfrksakcnpNKQCSGVTCK 66 577888888888877655566666665555454567777776 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0025 zf-TAZ 21 kCkklkkCkkvkkllkHvksCk 42 C ++ kC+ + + + H k C+ FUN_001188-T1 162 FCVRMDKCQGFNASVDHYKPCT 183 5878888888888888888886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (304 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 868 (0.0339793); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2939.46 // Query: FUN_001189-T1 [L=697] Description: FUN_001189 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-83 280.9 0.2 1.5e-83 280.4 0.2 1.2 1 Glyco_transf_64 Glycosyl transferase family 64 domain 1.1e-46 160.0 0.0 1.6e-46 159.5 0.0 1.2 1 Exostosin_GT47 Exostosin GT47 domain Domain annotation for each model (and alignments): >> Glyco_transf_64 Glycosyl transferase family 64 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 280.4 0.2 1.2e-87 1.5e-83 1 245 [] 436 680 .. 436 680 .. 0.98 Alignments for each domain: == domain 1 score: 280.4 bits; conditional E-value: 1.2e-87 Glyco_transf_64 1 ftvviltsakreelllklvkrvakspslkkivvlWns.ekpppeekkwpetgvpvtvvkqkkkslnnRflprseieTdavLslDddil.lstde 92 ft+v+l + r +++ k++ +++ psl kivv+Wn+ +k+pp+ kwp+ + pv+vv++k+++l+nRf+p++e++T+a+L++Dddil l de FUN_001189-T1 436 FTAVVLC-YDRVDTMFKVITKISDTPSLTKIVVVWNNvNKAPPSAAKWPKLSKPVKVVRTKENKLSNRFFPYNEVDTEAILAIDDDILmLTPDE 528 89****9.*****************************99999999*****************************************9625779* PP Glyco_transf_64 93 idfAFsVwrefpdrivGfvprshvwdessgewtytsesskeysmvLtgaaflhrkylelytkslpkelrklvdetqnCedilmnFlvakatrkp 186 ++f+F+ wrefpdr+vGf++r h+ ++ss++++y+se++++ smvLtg af h+++ +l+t+++p+ +r+ vd+++nCedi+mnF+v++ t+k+ FUN_001189-T1 529 LEFGFQAWREFPDRLVGFPGRVHTNQNSSSRFKYESEWTNNVSMVLTGCAFHHKYFSHLFTYMMPSYIRDWVDKHMNCEDIAMNFMVTNYTGKA 622 ********************************************************************************************** PP Glyco_transf_64 187 pvkvtkvkqleeekssekvglsskkeHlkkrskCinkfsevfgkmpLvesqlrldsvlf 245 p+kvt +k +++ ++ + +l+++++H+ +rs+C+n+f++++g+mpL ++r+d++lf FUN_001189-T1 623 PIKVTPRKRFRCPECVT-ESLWADPSHFVERSECLNEFVRAYGHMPLETVEFRADPLLF 680 ***************97.9*************************************998 PP >> Exostosin_GT47 Exostosin GT47 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.5 0.0 1.3e-50 1.6e-46 5 293 .. 84 355 .. 80 356 .. 0.87 Alignments for each domain: == domain 1 score: 159.5 bits; conditional E-value: 1.3e-50 Exostosin_GT47 5 lkVYvYdlpskfnedllencrelkswyaveqfllesllhsrvevrtsdpaeAdlffvpfyasldaerrelnsaltdarlsrellewlssqlpyWn 99 + VYv++ +f d + k+++++++ l++++++s+ ++t+d+++A ++++p+++ l+++ + + + + ++lp+W+ FUN_001189-T1 84 ISVYVHS-NNRFVDDG--GQVLNKELSQEFYDLISAIVESQ--YYTADMRKA-CIVIPLIDILNQSG-----------QYLKGIARILANLPSWK 161 6799985.55665552..222337899**************..*********.*************9...........6677777888888***6 PP Exostosin_GT47 100 rsnGrdHllvlsrpawafrr.takdvdwgralllnltssfseeqfrkgkdvalPypspfhpeigqlqdkspsnrRktllfFagel........rr 185 +Gr+Hll+++ p ++++ t+ dv+ ++a+l+ + sf ++ +r g+dv++P+++ + + ++ +++ ++l+++++++ + FUN_001189-T1 162 -DGGRNHLLFNMLPGGPPDYnTSLDVPIDKAILA--GGSFATWSYRSGFDVSIPVYNALTI---KNIHHPLKRSSEWLFISTQANmksafmmqLE 250 .8*****99999999999999*************..***********************99...999999999999***9999985554444334 PP Exostosin_GT47 186 reekgkirek........lleeckgnsdadickgkqctegrskeylellasstFClvppGdsptsarlfdallagCiPVilsdsielPfedvldw 272 + +l +c +d+ ++ +k+c+ ++ +y + l+++tFClv +G ++ + +l+dal +gCiPVi+s+++ lPf dvldw FUN_001189-T1 251 D--------IekenfgflVLNRC---PDDPHHIHKRCKGKTTYHYPDILQHATFCLVIRGVRLGQSTLMDALMMGCIPVIVSNDYILPFTDVLDW 334 4........3444666669****...999999999998755555*************************************************** PP Exostosin_GT47 273 rkfsvfvpekdipelksilrs 293 ++++v++ e +i+++ ++l++ FUN_001189-T1 335 KRAAVRIVESEIHRIPAVLKE 355 **************9999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (697 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 635 (0.0248581); expected 510.9 (0.02) Passed bias filter: 560 (0.0219221); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.43 # Mc/sec: 6585.07 // Query: FUN_001190-T1 [L=1288] Description: FUN_001190 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-24 84.5 0.2 2.6e-08 33.7 0.0 4.3 4 Beta-prop_THOC3 THOC3 beta-propeller domain 5.3e-22 78.9 0.3 2e-13 50.8 0.1 2.3 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 2.7e-21 76.6 0.2 1.2e-10 41.6 0.2 2.3 2 Beta-prop_WDR5 WDR5 beta-propeller domain 6.1e-16 59.1 0.0 1.3e-08 35.3 0.0 2.5 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 2.4e-14 53.6 5.5 2.6e-09 37.1 0.5 2.7 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 1.7e-12 47.5 0.0 4.9e-09 36.1 0.0 2.3 2 WD40_Prp19 Prp19 WD40 domain 4.9e-12 46.3 0.0 2.2e-06 27.8 0.0 2.8 3 Beta-prop_RIG_2nd RIG second beta-propeller 5.5e-12 46.2 0.0 1.9e-08 34.6 0.0 2.3 2 Beta-prop_EIPR1 EIPR1 beta-propeller 5.9e-12 45.9 2.1 0.027 14.1 0.1 4.2 4 WD40_WDHD1_1st WDHD1 first WD40 domain 1e-11 45.3 14.7 0.00027 21.8 0.0 6.0 5 WD40 WD domain, G-beta repeat 3.3e-11 43.6 0.0 1.4e-06 28.5 0.0 2.6 3 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 7.3e-11 42.1 0.2 0.00011 21.8 0.0 3.1 2 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 1.5e-10 41.4 0.0 1.1e-09 38.5 0.0 2.3 3 Beta-prop_EML_2 Echinoderm microtubule-associated 3.2e-08 33.5 0.0 0.00024 20.8 0.0 3.2 3 EIF3I EIF3I 4.5e-08 32.9 0.1 0.0044 16.5 0.0 3.1 3 WD40_Gbeta G protein beta WD-40 repeat protei 1.5e-06 28.8 0.5 6.1e-05 23.4 0.2 2.7 2 TPR_Sec16 Sec16 Sec23-binding domain 4.4e-06 26.4 0.0 0.12 11.9 0.0 3.2 3 WDR55 WDR55 2.2e-05 24.2 5.8 0.038 13.6 1.8 2.7 2 Beta-prop_Aladin Aladin seven-bladed propeller 0.00012 21.9 0.0 0.54 9.9 0.0 2.8 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 0.00032 21.3 0.0 0.00081 20.0 0.0 1.6 1 Prp18 Prp18 domain 0.0019 17.7 0.1 0.25 10.8 0.0 2.9 2 MIOS_WD40 MIOS, WD40 repeat 0.0071 16.6 0.4 0.0071 16.6 0.4 3.5 1 SRA1 Steroid receptor RNA activator (SR 0.0085 15.5 0.8 0.075 12.4 0.1 2.5 3 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 ------ inclusion threshold ------ 0.011 15.2 0.0 0.039 13.4 0.0 1.7 2 Beta-prop_VPS8 Vps8 beta-propeller 0.061 12.6 0.4 3.1 7.0 0.0 2.8 2 Beta-prop_SCAP SCAP Beta-propeller 0.21 12.6 0.0 0.67 11.0 0.0 1.8 1 DUF2408 Protein of unknown function (DUF24 0.3 11.0 0.0 0.56 10.1 0.0 1.4 1 Beta-prop_IFT122_2nd IFT122 second beta-propeller Domain annotation for each model (and alignments): >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 3.5e-07 0.00033 16 78 .. 88 155 .. 83 165 .. 0.81 2 ! 25.0 0.3 1.3e-08 1.2e-05 47 118 .. 170 248 .. 165 252 .. 0.68 3 ! 33.7 0.0 2.8e-11 2.6e-08 26 131 .. 242 352 .. 241 369 .. 0.75 4 ? 0.9 0.0 0.27 2.5e+02 219 250 .. 400 435 .. 394 443 .. 0.81 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 3.5e-07 Beta-prop_THOC3 16 rLasgsaDktvrvwnlek.....sklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrt 78 L gs++ + ++n++k +++s e + ht+ V++l ++p ++ lla++ sD+ + +Wd+ + FUN_001190-T1 88 LLIGGSDNGLISIYNAQKiisgdTDDSIVFESTKHTGPVQALDINPFKTSLLASGASDSEIFIWDLTN 155 577899999******9985443222233458899*******************************986 PP == domain 2 score: 25.0 bits; conditional E-value: 1.3e-08 Beta-prop_THOC3 47 dsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgenin...lawspdGkt.iavgskdd...tvslidvr 118 d+++++aw+ + +++la+as + +Wd+r+++++ +v+ ++ i ++w+pd t ++ +s+dd +++++d+r FUN_001190-T1 170 DNISCVAWNRQVQHILASASPCGRCVVWDLRKNEPIIKVSDQSAMIRckaVEWHPDVATqMVLASEDDrypVIQMWDLR 248 6778888888888888888887778888888888888888887777433477888743314445555435567777765 PP == domain 3 score: 33.7 bits; conditional E-value: 2.8e-11 Beta-prop_THOC3 26 vrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrt....gkstatvktkgen.inlawsp.dGktiavgskddtvs 113 +++w+l+ ++ + l+gh++ + ++aw p++pdll+++ +D+++ +W+ +t g+ t ++ t+++ + +aw p + +i+++s d +vs FUN_001190-T1 242 IQMWDLRFATSP-MKVLEGHQRGILSIAWCPQDPDLLMSCAKDNRILCWNPNTqdagGEITYELPTTSQWsFDVAWCPrNPAMICSSSFDGHVS 334 677888766544.3589*********************************99944444556666665554178****94567888888999*** PP Beta-prop_THOC3 114 lidvrtgkvkkeekfkke 131 ++ + g + +++ ++++ FUN_001190-T1 335 VFSLMGGGASSQDFNQQK 352 999887766555444444 PP == domain 4 score: 0.9 bits; conditional E-value: 0.27 Beta-prop_THOC3 219 vsFShdGkllAsasedk....tidiasvetgesvht 250 sFS+ Gkl+ +++++ +++i++v+t +++ + FUN_001190-T1 400 ASFSFGGKLISFGQTKDspiaQVNISQVTTEQELVN 435 59**********987653454799999999998765 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 1.1e-08 1e-05 140 211 .. 78 155 .. 77 162 .. 0.82 2 ! 50.8 0.1 2.1e-16 2e-13 51 208 .. 169 337 .. 162 355 .. 0.73 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.1e-08 WD40_CDC20-Fz 140 glkwspdgrllAsGgndn.tvkiwdlrsl.......spllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntnt 211 g++ s++++ l Gg+dn +++i++++++ s +++ t+h+ v+Al+ +p+k+slLa+G +D +i +w+ ++ FUN_001190-T1 78 GIDSSTSSSGLLIGGSDNgLISIYNAQKIisgdtddSIVFESTKHTGPVQALDINPFKTSLLASGA--SDSEIFIWDLTN 155 7888888888999999984689***998754443323577889*********************98..6*******9875 PP == domain 2 score: 50.8 bits; conditional E-value: 2.1e-16 WD40_CDC20-Fz 51 sdyvtsvkwsed.gelLavGtssgevelwdvekkkklrtleghss..rvgalawnenl...lssGsrdgk...ilhhDvrtkelevvktlkahkqe 137 d++++v+w+ + +++La ++ g++ +wd +k++ + +++ +s+ r a++w+ ++ ++ s+d + i+++D+r +++ +k l++h++ FUN_001190-T1 169 PDNISCVAWNRQvQHILASASPCGRCVVWDLRKNEPIIKVSDQSAmiRCKAVEWHPDVatqMVLASEDDRypvIQMWDLRFATSP-MKVLEGHQRG 263 5789999999653789999999999999999999999999877762255668887655445444544443344899999999865.6899999999 PP WD40_CDC20-Fz 138 vcglkwspdg.rllAsGgndntvkiwdlrslspllklt....ehkaavkAlaWcpwkkslLatGGGtaDktirlwn 208 + +++w p++ +ll s+++dn++ +w+ +++++ ++t + +aWcp ++ ++++ + D+++ +++ FUN_001190-T1 264 ILSIAWCPQDpDLLMSCAKDNRILCWNPNTQDAGGEITyelpTTSQWSFDVAWCPRNPAMICSSS--FDGHVSVFS 337 99999999543899999999999999998886533333113144444447999999999999875..366666655 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.6 0.2 1.3e-13 1.2e-10 57 204 .. 83 247 .. 35 248 .. 0.79 2 ! 35.2 0.0 1.2e-11 1.1e-08 29 120 .. 241 339 .. 229 349 .. 0.75 Alignments for each domain: == domain 1 score: 41.6 bits; conditional E-value: 1.3e-13 Beta-prop_WDR5 57 ssdskllasaSDDktvriwdve.......tgkllktlkgHtnyvfcvaFnp.kgnllvSGsfDetvrlWdvrtgkclktlpaHs...dpvsavdf 140 +s s ll+ +SD + i++++ +++ + + Ht v +++ np k++ll+SG+ D ++ +Wd+++ + t + d +s+v++ FUN_001190-T1 83 TSSSGLLIGGSDNGLISIYNAQkiisgdtDDSIVFESTKHTGPVQALDINPfKTSLLASGASDSEIFIWDLTNPSSPLTPGSKTlppDNISCVAW 177 345779***************988877655568899999***********857889***************997654333332233399****** PP Beta-prop_WDR5 141 nrdgt.livsssyDgliriwdtetgqclktlveddnp.pvsfvkFspn..gkyiLastlds..tirLwdy 204 nr+ + +++s+s g + +wd ++ + + ++ +++ + + v++ p+ +++Las+ d i++wd+ FUN_001190-T1 178 NRQVQhILASASPCGRCVVWDLRKNEPIIKVSDQSAMiRCKAVEWHPDvaTQMVLASEDDRypVIQMWDL 247 **97648899********************998765569********83356899999886335888885 PP == domain 2 score: 35.2 bits; conditional E-value: 1.2e-11 Beta-prop_WDR5 29 tikiwdve.egklektleghkkGisdvawss.dskllasaSDDktvriwdvetgk....llktlkgHtnyvfcvaFnpkg.nllvSGsfDetvrl 116 +i++wd++ ++ +k+legh++Gi ++aw + d ll+s++ D+ + w+ +t+ ++ +l +++ f va+ p++ ++ S+sfD v + FUN_001190-T1 241 VIQMWDLRfATSPMKVLEGHQRGILSIAWCPqDPDLLMSCAKDNRILCWNPNTQDaggeITYELPTTSQWSFDVAWCPRNpAMICSSSFDGHVSV 335 58888875145688999999999999999873578999999999999999987655555888899999999999998876367889999999988 PP Beta-prop_WDR5 117 Wdvr 120 + + FUN_001190-T1 336 FSLM 339 7765 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 3.8e-07 0.00036 42 102 .. 87 155 .. 44 161 .. 0.78 2 ! 35.3 0.0 1.3e-11 1.3e-08 31 183 .. 171 337 .. 164 338 .. 0.60 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 3.8e-07 Beta-prop_WDR3_1st 42 kklavGyadgsirlwdl.......esgelevtfngHksavtalafdkdg.srLasGskDtdiivwDvva 102 l G+++g i ++++ ++ ++ + + H++ v+al+ ++ + s LasG++D++i +wD+++ FUN_001190-T1 87 GLLIGGSDNGLISIYNAqkiisgdTDDSIVFESTKHTGPVQALDINPFKtSLLASGASDSEIFIWDLTN 155 4566788999******9444443222334455568***********9651678*************986 PP == domain 2 score: 35.3 bits; conditional E-value: 1.3e-11 Beta-prop_WDR3_1st 31 evtalaaspdgk.klavGyadgsirlwdlesgelevtfngHksavta..lafdkd.gsrLasGskDtd...iivwDv.vaeaglfrLkgHk 113 +++++a +++ + la+++ g +wdl+++e ++ + ++ + + +++++d ++++ +s+D i +wD+ a + + L+gH+ FUN_001190-T1 171 NISCVAWNRQVQhILASASPCGRCVVWDLRKNEPIIKVSDQSAMIRCkaVEWHPDvATQMVLASEDDRypvIQMWDLrFATSPMKVLEGHQ 261 5677777766441457777777777777777777777777777765522555555234566666665323366777733555666677777 PP Beta-prop_WDR3_1st 114 dqvtsvafleek.kvlvssSkDtliklWdletqhcvktlvgh..rsevwslals...kdekllvtgssdselrvwk 183 + s+a+++++ ++l+s++kD+ i +W+ +tq ++ + ++ ws+++ ++ ++ + s d +++v++ FUN_001190-T1 262 RGILSIAWCPQDpDLLMSCAKDNRILCWNPNTQDAGGEITYElpTTSQWSFDVAwcpRNPAMICSSSFDGHVSVFS 337 7777777775432777777777777777777777665544432256666666653334555666666677777665 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.1 0.5 2.7e-12 2.6e-09 44 187 .. 79 221 .. 57 248 .. 0.83 2 ! 17.4 1.1 2.8e-06 0.0026 80 166 .. 251 340 .. 225 362 .. 0.74 3 ? -2.7 0.0 3.9 3.7e+03 141 182 .. 798 837 .. 779 838 .. 0.75 Alignments for each domain: == domain 1 score: 37.1 bits; conditional E-value: 2.7e-12 Beta-prop_TEP1_2nd 44 vlglalsqkllasasedltvrlWskelltqpekaeslsslsvlrghtgavtccsfsl.dGgllatggrdrsllcWdvrvpkaPvlirslla 133 + + ++s+ ll s++ +++++ ++++ ++ +s+ s htg+v ++ + +lla+g+ d ++++Wd+ +p +P+ s + FUN_001190-T1 79 IDSSTSSSGLLIGGSDNGLISIYNAQKIISGDTDDSIVFES--TKHTGPVQALDINPfKTSLLASGASDSEIFIWDLTNPSSPLTPGS-KT 166 555678999*******************9999988886655..69********9998356679********************87766.56 PP Beta-prop_TEP1_2nd 134 chrdWvtgcaWtkd..dllvscssdGsvglWdiekeqrlgkflGhqsavsavvave 187 d +++ aW ++ ++l s+s G +Wd++k++ + k qsa+ ave FUN_001190-T1 167 LPPDNISCVAWNRQvqHILASASPCGRCVVWDLRKNEPIIKVS-DQSAMIRCKAVE 221 678********9853389*******************999965.678877777666 PP == domain 2 score: 17.4 bits; conditional E-value: 2.8e-06 Beta-prop_TEP1_2nd 80 lsslsvlrghtgavtccsfsl.dGgllatggrdrsllcWdvrvpkaP.vlirsllachrdWvtgcaWt..kddllvscssdGsvglWdiek 166 s+++vl gh+ ++ ++ + d +ll + ++d+ +lcW+ ++ +a +++ l++ W aW + +++ s+s dG v+++ + FUN_001190-T1 251 TSPMKVLEGHQRGILSIAWCPqDPDLLMSCAKDNRILCWNPNTQDAGgEITYELPT-TSQWSFDVAWCprNPAMICSSSFDGHVSVFSLMG 340 467889******99999998625677999***********9998765155556655.6779999999832457999999****99987655 PP == domain 3 score: -2.7 bits; conditional E-value: 3.9 Beta-prop_TEP1_2nd 141 gcaWtkddllvscssdGsvglWdiekeqrlgkflGhqsavsa 182 gc t + l++ ++Gs+g+ + +f Gh sa sa FUN_001190-T1 798 GCLETAMGYLMTVNDEGSLGVLKDRL--FNAQFPGHISAASA 837 77778888888889999998754443..33689***999886 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.1 0.0 5.2e-12 4.9e-09 19 184 .. 85 268 .. 75 269 .. 0.76 2 ! 12.9 0.0 6.1e-05 0.057 6 80 .. 261 340 .. 258 359 .. 0.74 Alignments for each domain: == domain 1 score: 36.1 bits; conditional E-value: 5.2e-12 WD40_Prp19 19 knlvltGGaDk.nvvlfdr.......esekvlatlkghtkkvtavafhp.sedvlvsasaDktvrvwkkeeketaatlkkhk...aevtslsvhp. 101 ++ +l GG+D+ + ++++ ++++++ + ++ht v+a+ ++p ++++l s+++D+++ +w+ ++ + t +++ +++++++ + FUN_001190-T1 85 SSGLLIGGSDNgLISIYNAqkiisgdTDDSIVFESTKHTGPVQALDINPfKTSLLASGASDSEIFIWDLTNPSSPLTPGSKTlppDNISCVAWNRq 180 34455566665156678874444444488999999*************9667899**************998766554333322379999998761 PP WD40_Prp19 102 tgdylvsaskDgtwalhdletgktllkvkdeeskeaitsaqfHPD..GlllgtGtkdg..tvkiWDiksqknvas.leghsgavtsla 184 +++ l+sas g + ++dl++++ + kv+d+++ + +++++HPD +++ + ++d+ ++++WD++ ++ ++ legh+ + s+a FUN_001190-T1 181 VQHILASASPCGRCVVWDLRKNEPIIKVSDQSAMIRCKAVEWHPDvaTQMVLASEDDRypVIQMWDLRFATSPMKvLEGHQRGILSIA 268 566778999999*********************************4434555555554448*******98877762699*99998886 PP == domain 2 score: 12.9 bits; conditional E-value: 6.1e-05 WD40_Prp19 6 kpgilaldlnpsdknlvltGGaDknvvlfdrese....kvlatlkghtkkvtavafhpsed.vlvsasaDktvrvwkkee 80 + gil+++ +p+d++l++++++D+++ ++ +++ +++ +l ++ +va+ p++ ++ s+s D++v v++ FUN_001190-T1 261 QRGILSIAWCPQDPDLLMSCAKDNRILCWNPNTQdaggEITYELPTTSQWSFDVAWCPRNPaMICSSSFDGHVSVFSLMG 340 78999999999999999999999999999987551111566666677777889999987752678899999999998643 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.8 0.0 2.4e-09 2.2e-06 130 249 .. 87 204 .. 78 224 .. 0.82 2 ! 14.7 0.1 2.3e-05 0.021 171 275 .. 220 326 .. 207 328 .. 0.72 3 ! 14.0 0.0 3.8e-05 0.036 164 241 .. 260 335 .. 249 352 .. 0.55 Alignments for each domain: == domain 1 score: 27.8 bits; conditional E-value: 2.4e-09 Beta-prop_RIG_2nd 130 slLlvgtedGalqllerkkelekays.kllkqeallsryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsv 220 lL+ g+++G +++++++k + + +++ +++ ++ ++ ++p+++ lA a d+ i+i ++++ ++ l+ ++ + ++i++v FUN_001190-T1 87 GLLIGGSDNGLISIYNAQKIISGDTDdSIVFESTKHTGPVQALDINPFKTSLLASGASDSEIFIWDLTNPSSPLTPGS---KTLPPDNISCV 175 5677789***********966655541455566667789999999***********************9988887765...4568899**** PP Beta-prop_RIG_2nd 221 kwsnansnlllsfsidgkvkvWdleepek 249 +w+++ +++l s s g+ vWdl+++e FUN_001190-T1 176 AWNRQVQHILASASPCGRCVVWDLRKNEP 204 ************************98874 PP == domain 2 score: 14.7 bits; conditional E-value: 2.3e-05 Beta-prop_RIG_2nd 171 iawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekeeltitykcpmlc 262 + w p +++ +++d+ ++++ + t + + ++ i s++w +++ +ll+s+ d+++ W+ +++ +ity+ p ++ FUN_001190-T1 220 VEWHPDVATQMVLASEDDRYPVIQMW--DLRFATSPMKVLEGHQRGILSIAWCPQDPDLLMSCAKDNRILCWNPNTQDAGG-EITYELPTTS 308 56677777777777777777776665..555666667778899*******************************9998843.4555555443 PP Beta-prop_RIG_2nd 263 .....glFlPtdenivlc 275 + P ++ ++ + FUN_001190-T1 309 qwsfdVAWCPRNPAMICS 326 111224577777777654 PP == domain 3 score: 14.0 bits; conditional E-value: 3.8e-05 Beta-prop_RIG_2nd 164 lsryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkv 241 ++r i iaw+p + + l +a+d+ i + ++++ + + + +++ +v+w ++n +++ s+s+dg+v v FUN_001190-T1 260 HQRGILSIAWCPQDPDLLMSCAKDNRILCWNPNTQDAG--GEITYELPTTSQWSFDVAWCPRNPAMICSSSFDGHVSV 335 34455555555555555555555555555444433333..33333444444445555555555555555555555555 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.00094 0.89 209 280 .] 78 151 .. 61 151 .. 0.80 2 ! 34.6 0.0 2e-11 1.9e-08 154 280 .] 165 289 .. 148 289 .. 0.81 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00094 Beta-prop_EIPR1 209 avdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHt..vkkvlfNpfydeLilscssdstlkLw 280 +d +++ + l+ d+g + i+ s ++++ +Ht v++ +Npf+ L+ s++sds + +w FUN_001190-T1 78 GIDSSTSSSGLLIGGSDNGLISIYNAQKIISGDTDDSIVFESTKHTgpVQALDINPFKTSLLASGASDSEIFIW 151 6888999999999999999999999885444445555556665665449********************99887 PP == domain 2 score: 34.6 bits; conditional E-value: 2e-11 Beta-prop_EIPR1 154 yslggeelrvaAldphdsslvlvace.sglqliDlRakkkksvanvetlhgfgkvravdfdpakkn.klltagddg..vvlihDiRydgsstve 243 +l +++++ A++ ++ + a+ ++DlR+ ++ v+ + + +av+++p + ++l+++dd v++++D+R + FUN_001190-T1 165 KTLPPDNISCVAWNRQVQHILASASPcGRCVVWDLRKNEPII--KVSDQSAMIRCKAVEWHPDVATqMVLASEDDRypVIQMWDLR----FATS 252 55566899*****987777666666688999*****999988..999999999********976650556778885336*******....6778 PP Beta-prop_EIPR1 244 klkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 ++k+l++h+ + ++++ p+ +L++sc+ d+ + w FUN_001190-T1 253 PMKVLEGHQRGILSIAWCPQDPDLLMSCAKDNRILCW 289 9999***************************987655 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.1 2.9e-05 0.027 100 160 .. 88 156 .. 77 165 .. 0.70 2 ! 13.7 0.1 3.8e-05 0.036 223 282 .. 170 232 .. 161 241 .. 0.78 3 ! 13.7 0.0 3.9e-05 0.036 100 162 .. 229 296 .. 225 318 .. 0.80 4 ? 2.4 0.0 0.11 1e+02 136 162 .. 316 343 .. 308 374 .. 0.71 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.9e-05 WD40_WDHD1_1st 100 llaagseDftikvvsv.......edsskqktleghkapvlsvaldpkg.eylaSsscDGtvkiWdiesk 160 ll+ gs++ i +++ +d s +++ + h++pv +++++p + +laS ++D ++ iWd+++ FUN_001190-T1 88 LLIGGSDNGLISIYNAqkiisgdTDDSIVFESTKHTGPVQALDINPFKtSLLASGASDSEIFIWDLTNP 156 4455555566666665222222234466777779************653789999**********9975 PP == domain 2 score: 13.7 bits; conditional E-value: 3.8e-05 WD40_WDHD1_1st 223 edisivafSpcGky.laaatvdgeilvWdvatkeliervkhe.kklaitslaWnpk.eneLaf 282 ++is+va+ + ++ la+a+ g+ +vWd+ ++e i +v+ + ++ ++ W+p+ ++++++ FUN_001190-T1 170 DNISCVAWNRQVQHiLASASPCGRCVVWDLRKNEPIIKVSDQsAMIRCKAVEWHPDvATQMVL 232 5799****9987552799999************9998886551566788899***95556554 PP == domain 3 score: 13.7 bits; conditional E-value: 3.9e-05 WD40_WDHD1_1st 100 llaagseDftikvvsv....edsskqktleghkapvlsvaldpkg.eylaSsscDGtvkiWdieskec 162 ++ +seD v+++ +s k+legh+ +ls+a +p++ +l+S + D + W+ ++++ FUN_001190-T1 229 QMVLASEDDRYPVIQMwdlrFATSPMKVLEGHQRGILSIAWCPQDpDLLMSCAKDNRILCWNPNTQDA 296 678899998877777722233457899*****************97899************9988765 PP == domain 4 score: 2.4 bits; conditional E-value: 0.11 WD40_WDHD1_1st 136 ldpkg.eylaSsscDGtvkiWdieskec 162 +p++ ++ Sss DG+v ++++ + FUN_001190-T1 316 WCPRNpAMICSSSFDGHVSVFSLMGGGA 343 5555536789***********9976543 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.5 2.5 2.4e+03 21 39 .] 84 102 .. 71 102 .. 0.75 2 ! 14.4 0.1 6.5e-05 0.061 8 39 .] 120 152 .. 106 152 .. 0.85 3 ! 7.8 0.2 0.0081 7.7 12 39 .] 170 198 .. 164 198 .. 0.86 4 ! 21.8 0.0 2.9e-07 0.00027 2 39 .] 252 290 .. 251 290 .. 0.83 5 ? 6.7 0.2 0.018 17 15 38 .. 312 336 .. 298 337 .. 0.75 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2.5 WD40 21 pdgsllasgsdDgtvklWd 39 +++ ll+ gsd+g + +++ FUN_001190-T1 84 SSSGLLIGGSDNGLISIYN 102 444556788*9*9999986 PP == domain 2 score: 14.4 bits; conditional E-value: 6.5e-05 WD40 8 kgHtsgVtslafspdgsl.lasgsdDgtvklWd 39 + Ht++V +l+++p + lasg+ D+ + +Wd FUN_001190-T1 120 TKHTGPVQALDINPFKTSlLASGASDSEIFIWD 152 579999*****88888883579977*******9 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0081 WD40 12 sgVtslafspdgsl.lasgsdDgtvklWd 39 ++++++a++ ++ las+s g++ +Wd FUN_001190-T1 170 DNISCVAWNRQVQHiLASASPCGRCVVWD 198 579***********44688*********9 PP == domain 4 score: 21.8 bits; conditional E-value: 2.9e-07 WD40 2 kllrtlkgHtsgVtsla.fspdgsllasgsdDgtvklWd 39 +++++l+gH+ g+ s+a ++d +ll s+++D+++ +W+ FUN_001190-T1 252 SPMKVLEGHQRGILSIAwCPQDPDLLMSCAKDNRILCWN 290 57899****999*****5555555567***********7 PP == domain 5 score: 6.7 bits; conditional E-value: 0.018 WD40 15 tslafspdgslla.sgsdDgtvklW 38 ++a++p ++ ++ s+s Dg+v ++ FUN_001190-T1 312 FDVAWCPRNPAMIcSSSFDGHVSVF 336 57889999999653789*****997 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.0 0.00014 0.13 168 224 .. 92 155 .. 79 161 .. 0.86 2 ! 28.5 0.0 1.4e-09 1.4e-06 161 263 .. 181 289 .. 163 291 .. 0.82 3 ? -3.8 0.0 9.8 9.3e+03 205 223 .. 321 339 .. 312 346 .. 0.71 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00014 Beta-prop_WDR36-Utp21_1st 168 glasGeivlhnikk.......detllklkqeegpvtsisFrtDgepvlatgsssGdialwdLek 224 g +G i ++n +k d ++++ ++++gpv+++ ++++la+g s+ +i++wdL + FUN_001190-T1 92 GSDNGLISIYNAQKiisgdtdDSIVFESTKHTGPVQALDINPFKTSLLASGASDSEIFIWDLTN 155 55678888888877777777689999999999******************************86 PP == domain 2 score: 28.5 bits; conditional E-value: 1.4e-09 Beta-prop_WDR36-Utp21_1st 161 aldvvaiglasGeivlhnikkdetllklkqeeg..pvtsisFrtDgepvlatgss...sGdialwdLekrrlvhvlrnaHeggv 239 + +++a + G++v+ +++k+e ++k++ +++ ++ ++ D + ++ +s+ i +wdL + + + H+ g+ FUN_001190-T1 181 VQHILASASPCGRCVVWDLRKNEPIIKVSDQSAmiRCKAVEWHPDVATQMVLASEddrYPVIQMWDLRFATSPMKVLEGHQRGI 264 5678899999*******************986645788899999988888888761225679******99777777789***** PP Beta-prop_WDR36-Utp21_1st 240 tkleflpgqp.llvtsgaDNslkew 263 ++ + p+ p ll++ ++DN + w FUN_001190-T1 265 LSIAWCPQDPdLLMSCAKDNRILCW 289 ********987999********999 PP == domain 3 score: -3.8 bits; conditional E-value: 9.8 Beta-prop_WDR36-Utp21_1st 205 epvlatgsssGdialwdLe 223 +++++++s +G++ ++ L FUN_001190-T1 321 PAMICSSSFDGHVSVFSLM 339 3444555569999999985 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.2 2.5e-05 0.024 37 184 .. 89 226 .. 77 250 .. 0.72 2 ! 21.8 0.0 1.1e-07 0.00011 123 202 .. 254 339 .. 248 368 .. 0.80 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.5e-05 Beta-prop_CAF1B_HIR1 37 asgGaDs.hvliWkvkieeegkvklelladltrhqkavnvvrfspsge.lLasgdDesviiiWklkeeeeeinlleeeeeenketwlvl 123 gG+D + i++ ++ +g+++ +++ + t+h+ +v + p ++ lLasg +s i+iW l++ ++ +l FUN_001190-T1 89 LIGGSDNgLISIYNAQKIISGDTDDSIVFESTKHTGPVQALDINPFKTsLLASGASDSEIFIWDLTNPSS--PLT-----------PGS 164 56788762578999999999************************9664399*************998864..322...........223 PP Beta-prop_CAF1B_HIR1 124 kvlrGhledvyDlswspdskk.lisgsvDntailWdvekgkklailkdhkgfvq..gvawdPkn 184 k+l +++ ++w ++ ++ l s+s ++Wd++k + + ++d+ +++ +v w P FUN_001190-T1 165 KTLP--PDNISCVAWNRQVQHiLASASPCGRCVVWDLRKNEPIIKVSDQSAMIRckAVEWHPDV 226 4553..4677777887776651456777777888888888888777877777643367777754 PP == domain 2 score: 21.8 bits; conditional E-value: 1.1e-07 Beta-prop_CAF1B_HIR1 123 lkvlrGhledvyDlswspds.kklisgsvDntailWdvek....gkklailkdhkgfvqgvawdPkn.qyvatlssDrslrifdik 202 +kvl Gh + ++w p++ l+s + Dn ++ W+ + g+ + l ++ vaw+P+n ++++ s D ++ +f++ FUN_001190-T1 254 MKVLEGHQRGILSIAWCPQDpDLLMSCAKDNRILCWNPNTqdagGEITYELPTTSQWSFDVAWCPRNpAMICSSSFDGHVSVFSLM 339 79**************9876256789**********97652222345566788899999*******94467888889999999875 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.0 0.0022 2.1 200 265 .. 83 152 .. 77 153 .. 0.74 2 ! 38.5 0.0 1.2e-12 1.1e-09 2 156 .. 127 294 .. 126 319 .. 0.81 3 ? -1.6 0.0 2 1.9e+03 75 115 .. 302 343 .. 294 359 .. 0.69 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0022 Beta-prop_EML_2 200 sksekllatgddfGkvklfkyPct....kkkakykkykgHsshVtnvrFladdsylistGGaDasvfqWk 265 ++s+ ll+ g d+G +++++ + ++++ + + + H+ V +++ + ++ l+ G+ D+ +f W FUN_001190-T1 83 TSSSGLLIGGSDNGLISIYNAQKIisgdTDDSIVFESTKHTGPVQALDINPFKTSLLASGASDSEIFIWD 152 4566789999999999999988751111333445666889999999999999999999999999999996 PP == domain 2 score: 38.5 bits; conditional E-value: 1.2e-12 Beta-prop_EML_2 2 wGLathpsep.qfvTagdDktvrlWdlekkklva....kvklekearsvafspdgkll.avGlkdGsvlvldaetleevvevkdrkeaisd..i 87 +L+++p + +++ D+ + +Wdl + + k+ +++++va++ + +++ a ++ G+ +v+d ++ e +++v+d++ i++ + FUN_001190-T1 127 QALDINPFKTsLLASGASDSEIFIWDLTNPSSPLtpgsKTLPPDNISCVAWNRQVQHIlASASPCGRCVVWDLRKNEPIIKVSDQSAMIRCkaV 220 6999***99725589999*********985443312214445689*******9888761555679*****************999887754449 PP Beta-prop_EML_2 88 kfspdg.klLavgshdnk...iylYdvskkykkvgklkghssfithlDws.edskylqsnsgdyellfwdaktg 156 +++pd + ++++s+d + i+++d++ + +++l+gh+ i+++ w +d ++l+s +d+++l+w+ +t FUN_001190-T1 221 EWHPDVaTQMVLASEDDRypvIQMWDLRFATSPMKVLEGHQRGILSIAWCpQDPDLLMSCAKDNRILCWNPNTQ 294 ****96256788999986566889999999*******************846999**************98775 PP == domain 3 score: -1.6 bits; conditional E-value: 2 Beta-prop_EML_2 75 vevkdrkeaisdikfspdg.klLavgshdnkiylYdvskkyk 115 +e+ +++++ d++++p + ++++ +s d+++ ++++ + FUN_001190-T1 302 YELPTTSQWSFDVAWCPRNpAMICSSSFDGHVSVFSLMGGGA 343 556667788888999996526777778899999999865444 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.5 0.0 0.0059 5.6 50 83 .. 121 155 .. 117 166 .. 0.88 2 ? 2.4 0.0 0.1 96 148 219 .. 171 246 .. 155 252 .. 0.72 3 ! 20.8 0.0 2.6e-07 0.00024 5 104 .. 256 360 .. 251 389 .. 0.72 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0059 EIF3I 50 GheGavwsidvds.ettllvtgsadntvklWdvet 83 h+G v ++d++ +t+ll++g++d+++ +Wd+++ FUN_001190-T1 121 KHTGPVQALDINPfKTSLLASGASDSEIFIWDLTN 155 599********974788899************875 PP == domain 2 score: 2.4 bits; conditional E-value: 0.1 EIF3I 148 kvtvalwsaldktiitg.hedgeiskydlktgeklksvkehekqi..tdlqlskd.ktylitaskDktaklldvet 219 ++++++w+ + ++i+++ + g+ + +dl+++e + +v+++++ i + +++++d t ++ as D ++++ + FUN_001190-T1 171 NISCVAWNRQVQHILASaSPCGRCVVWDLRKNEPIIKVSDQSAMIrcKAVEWHPDvATQMVLASEDDRYPVIQMWD 246 5677888887777766515578999999999999888888877762256778877346788888888777666655 PP == domain 3 score: 20.8 bits; conditional E-value: 2.6e-07 EIF3I 5 llkGheRaltqikyn.reGDllfsvakdkkasvwysenGerlG..tyeGheGavwsidvds...ettllvtgsadntvklWdvetGkelktletkt 94 +l+Gh+R + i + ++ Dll+s+akd+++ +w + + G tye + + ws dv + + +++++s d +v ++++ G ++ +++ FUN_001190-T1 256 VLEGHQRGILSIAWCpQDPDLLMSCAKDNRILCWNPNTQDAGGeiTYELPTTSQWSFDVAWcprNPAMICSSSFDGHVSVFSLMGGGASSQ-DFNQ 350 69**********9863899***************876555555669**************94434567899999*9999999987754433.3333 PP EIF3I 95 avrsvefses 104 + +f+ + FUN_001190-T1 351 QKVMSAFDAD 360 2223344444 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 4.6e-06 0.0044 181 311 .. 120 260 .. 105 261 .. 0.76 2 ! 13.2 0.0 4.9e-05 0.046 49 127 .. 255 339 .. 247 346 .. 0.83 3 ? 0.3 0.0 0.39 3.7e+02 25 71 .. 632 678 .. 625 683 .. 0.88 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 4.6e-06 WD40_Gbeta 181 vghtgdvmslslap.dtrlfvsgacdasaklwdvreglcrqtfighe...sdinaiaffpnge.alatgsddatcrlfdlradqellvyshdniic 271 + htg v +l + p t l+ sga d+ + +wd+ + t + +i ++a+ + + la+ s c ++dlr ++ ++ s ++ + FUN_001190-T1 120 TKHTGPVQALDINPfKTSLLASGASDSEIFIWDLTNPSSPLTPGSKTlppDNISCVAWNRQVQhILASASPCGRCVVWDLRKNEPIIKVSDQSAMI 215 67***********95578899**************98887775444322267888888877651567889999******************99877 PP WD40_Gbeta 272 gitsvaf..sksgrlllagyddfn..cnvwda.lkadragvlagh 311 +v + + +++la dd ++wd + + + vl gh FUN_001190-T1 216 RCKAVEWhpDVATQMVLASEDDRYpvIQMWDLrFATSPMKVLEGH 260 777776622578899999999964225778851444556677776 PP == domain 2 score: 13.2 bits; conditional E-value: 4.9e-05 WD40_Gbeta 49 rtlrghlakiyamhwg.tdsrllvsasqdgkliiwdsyttnk....vhaiplrsswvmtcayapsgnfvacg.gldnicsiynlk 127 + l gh i ++ w+ d ll+s+++d +++ w+ t + + +p s w + +a++p + c +d +s+++l FUN_001190-T1 255 KVLEGHQRGILSIAWCpQDPDLLMSCAKDNRILCWNPNTQDAggeiTYELPTTSQWSFDVAWCPRNPAMICSsSFDGHVSVFSLM 339 6899***********846899***************999865222267889*************988777752689999999885 PP == domain 3 score: 0.3 bits; conditional E-value: 0.39 WD40_Gbeta 25 cadatlaeivagldvvgriqmrtrrtlrghlakiyamhwgtdsrllv 71 ada l i+ g d + riq r + h+a++ ++ + d r +v FUN_001190-T1 632 MADAFLLAIAGGPDLLARIQTRYFEKSKSHVARLMSVVVNRDWRDIV 678 58999999**************************9998888877766 PP >> TPR_Sec16 Sec16 Sec23-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.2 6.4e-08 6.1e-05 1 230 [. 610 807 .. 610 816 .. 0.76 2 ? -2.7 0.0 6 5.7e+03 248 288 .. 1184 1220 .. 1180 1225 .. 0.76 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 6.4e-08 TPR_Sec16 1 iqklLlkGdrekAlqlAldkklWahALliasllgkelwkevvqefvrkevkssgensesLavlyqvfaGnseeavdelvpvsaraglqeskeaeea 96 i++ Ll+G+ e+A++++l + a A+l+a + g++l +++ +++ +k+ + a l++v+++ ++v+ + + FUN_001190-T1 610 ISQALLTGNFEAAVDVCLYADRMADAFLLAIAGGPDLLARIQTRYFEKSK-------SHVARLMSVVVNRDW---RDIVE-------------SCV 682 7899*****************************************99988.......344555555555544...34454.............567 PP TPR_Sec16 97 ldkWretvalvlsnrspsdseaLle.lGklLaskgrv..eaahicfllalsqesvfgglddpsarlvllgadhvrfessfakdleailltEvyEya 189 l++Wre +a+++ +++ +aL+ lG+ L ++g+ + +c++ a + e ++v ++ +++ +++ + l E++E + FUN_001190-T1 683 LENWREALAALVTYAKAEEFTALCDlLGQRLEQEGDEhcANSMVCYICAGNVE-----------KFVSCWTK------NMPAEPSPLALQELIEKV 761 8******************88888737******98761155679*****4443...........34433333......457888999999999999 PP TPR_Sec16 190 lslspaak......ekfaglphLlayKlqhAavLaelGlvseAqkYc 230 + l++a++ +g p L++ ++A +La +G ++A Y FUN_001190-T1 762 MILKKAVErerrlfV-DSGSPILAEKLSKYAEILAAQGCLETAMGYL 807 999987776654422.2455666665567899999999999998886 PP == domain 2 score: -2.7 bits; conditional E-value: 6 TPR_Sec16 248 hptllaeledLserLsqspkesksswisKpsldkvwgsldk 288 h tl ++++ L+er +++ + + +K +ld v+ l++ FUN_001190-T1 1184 HLTLQETFNGLAERCKNTAN----NPHTKRKLDDVSKRLEA 1220 55678888999999999885....44689999999998886 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.9 0.0 0.00012 0.12 93 179 .. 120 212 .. 93 220 .. 0.46 2 ! 9.8 0.0 0.00056 0.53 107 144 .. 182 219 .. 170 237 .. 0.84 3 ! 8.8 0.0 0.0011 1.1 107 221 .. 229 351 .. 223 355 .. 0.66 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00012 WDR55 93 kahespiysl..lvidenllatGdddGtvklWDlRkkk.avm..elkehedyisdlvvdee.kklLlatsgdGtltvfnirkkklevqseeye 179 + h+ p+++l + lla+G d + +WDl + + +++ + + d is+++ +++ +++L ++s G v+++rk++ ++ +++ FUN_001190-T1 120 TKHTGPVQALdiNPFKTSLLASGASDSEIFIWDLTNPSsPLTpgSKTLPPDNISCVAWNRQvQHILASASPCGRCVVWDLRKNEPIIKVSDQS 212 334444443311345555566666666666666555431222212222345666665554413333344555555555555555433333333 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00056 WDR55 107 enllatGdddGtvklWDlRkkkavmelkehedyisdlv 144 +++la++ G +WDlRk+++++++++++ +i + + FUN_001190-T1 182 QHILASASPCGRCVVWDLRKNEPIIKVSDQSAMIRCKA 219 689999**********************9999997655 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0011 WDR55 107 enllatGddd.GtvklWDlRkkkavme.lkehedyisdlvv.deekklLlatsgdGtltvfnirkkk..levqseeyeeells..lalvkeekkvv 195 + +la+ dd ++++WDlR ++ m+ l+ h+ i +++ ++ lL+++ d + ++n ++++ e++ e + s +a + ++ ++ FUN_001190-T1 229 QMVLASEDDRyPVIQMWDLRFATSPMKvLEGHQRGILSIAWcPQDPDLLMSCAKDNRILCWNPNTQDagGEITYELPTTSQWSfdVAWCPRNPAMI 324 56778888863589******9876665167788889999761566778888889999999998887623233333333333332256667777777 PP WDR55 196 vGss.eGklylfnwgefgahsdrfpgh 221 ++ss +G++++f+ ga s f+++ FUN_001190-T1 325 CSSSfDGHVSVFSLMGGGASSQDFNQQ 351 776557888888877777777777655 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 1.8 4e-05 0.038 60 207 .. 124 227 .. 98 248 .. 0.47 2 ! 12.3 1.1 9.9e-05 0.094 64 143 .. 219 294 .. 203 328 .. 0.54 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 4e-05 Beta-prop_Aladin 60 ksvaslaWrPlsaselavac.esgvlvWtvdptslatrpssssaqvLkrpghspvtsvaWspkGd.lLvsaspvdtsilvWdvaketav.pLr 149 v +l P+ +s la + +s +++W++ s p s++ L + +vaW+ + + +L+sasp+ +vWd k++ + ++ FUN_001190-T1 124 GPVQALDINPFKTSLLASGAsDSEIFIWDLTNPSSPLTPGSKT---LPP---DNISCVAWNRQVQhILASASPCGR-CVVWDLRKNEPIiKVS 209 3455555556666666554313456666554333333333332...222...345555665554314555555543.4556655544330222 PP Beta-prop_Aladin 150 rvgg.ggvsllkwspdgskllaatpssvfrvwetetWtcerWtvlkgrvqaacwspdgs 207 + + ++w pd FUN_001190-T1 210 DQSAmIRCKAVEWHPD-----------------------------------------VA 227 2211133444555554.........................................32 PP == domain 2 score: 12.3 bits; conditional E-value: 9.9e-05 Beta-prop_Aladin 64 slaWrPlsaselavaces....gvlvWtvdptslatrpssssaqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdvake 143 +++W+P a+++ a e+ + +W++ r ++s ++vL+ + + + s+aW p+ L+ ++++d+ il W+ +++ FUN_001190-T1 219 AVEWHPDVATQMVLASEDdrypVIQMWDL-------RFATSPMKVLEGH-QRGILSIAWCPQDPDLLMSCAKDNRILCWNPNTQ 294 34455555555555544311112233332.......3334444444432.3456666666665555555555666666665554 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.0 0.0068 6.4 70 114 .. 113 158 .. 78 199 .. 0.63 2 ! 9.1 0.0 0.001 0.94 174 270 .. 122 223 .. 113 239 .. 0.75 3 ! 9.9 0.0 0.00057 0.54 189 249 .. 230 294 .. 225 338 .. 0.69 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0068 Beta-prop_WDR3_2nd 70 aelletieahegavwsvaltpdekgl.vtggaDkkvkfwefelvee 114 +++ + + h+g v++++++p +++l +g++D+++ +w+++ ++ FUN_001190-T1 113 DSIVFESTKHTGPVQALDINPFKTSLlASGASDSEIFIWDLTNPSS 158 3445556789999999999997776515778899999999986655 PP == domain 2 score: 9.1 bits; conditional E-value: 0.001 Beta-prop_WDR3_2nd 174 hklPvlsldis.sDsklivtgsaDknikiwGldfGDch...kslfahddsvmsvafvpk.tHylfsagkdkkvkyWDadkfekiqtlegha 259 h+ Pv +ldi ++l+++g++D +i iw l s + d++ va+ ++ H l sa+ ++ WD k e i++++ ++ FUN_001190-T1 122 HTGPVQALDINpFKTSLLASGASDSEIFIWDLTNPSSPltpGSKTLPPDNISCVAWNRQvQHILASASPCGRCVVWDLRKNEPIIKVSDQS 212 7789999999746889999999999999999876554311123333458899999887626999999999999999999999999999999 PP Beta-prop_WDR3_2nd 260 gevwalavssk 270 + +++ av + FUN_001190-T1 213 AMIRCKAVEWH 223 99999998644 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00057 Beta-prop_WDR3_2nd 189 livtgsaDk..nikiwGldfGDc.hkslfahddsvmsvafvpkt.HylfsagkdkkvkyWDadkf 249 +++++ D+ i++w l f k l +h+ ++s+a+ p+ l+s++kd+++ W+ ++ FUN_001190-T1 230 MVLASEDDRypVIQMWDLRFATSpMKVLEGHQRGILSIAWCPQDpDLLMSCAKDNRILCWNPNTQ 294 45555555533489999999865368889999999999999886367899999999999987665 PP >> Prp18 Prp18 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 8.6e-07 0.00081 15 76 .. 1191 1252 .. 1184 1261 .. 0.86 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 8.6e-07 Prp18 15 leereeeekksaegkkaaatlkqtkedlkpLlkklkkkkleedileslaeivkalqereyvk 76 ++ e+ k++a++ ++++ l + ++ l+ L +kl+++k+++ ile l+ei +a+q+r+y + FUN_001190-T1 1191 FNGLAERCKNTANNPHTKRKLDDVSKRLEALYDKLREQKMSNPILEGLHEIAQACQDRDYPR 1252 555566778888899999999***************************************76 PP >> MIOS_WD40 MIOS, WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.085 80 199 238 .. 185 226 .. 128 244 .. 0.64 2 ! 10.8 0.0 0.00026 0.25 207 253 .. 242 288 .. 237 309 .. 0.90 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.085 MIOS_WD40 199 vasf.yegqvaiwdlrkfekpvltlteqpkpl..tkvawcptr 238 +as g+ +wdlrk e p++ +++q + v w p FUN_001190-T1 185 LASAsPCGRCVVWDLRKNE-PIIKVSDQSAMIrcKAVEWHPDV 226 4443135889999999965.89999999876521356787754 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00026 MIOS_WD40 207 vaiwdlrkfekpvltlteqpkpltkvawcptrtgllatltrdsniir 253 + +wdlr p+ l + + + +awcp ll + ++d+ i+ FUN_001190-T1 242 IQMWDLRFATSPMKVLEGHQRGILSIAWCPQDPDLLMSCAKDNRILC 288 579***************************************99875 PP >> SRA1 Steroid receptor RNA activator (SRA1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.4 7.5e-06 0.0071 42 131 .. 1190 1281 .. 1109 1287 .. 0.76 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 7.5e-06 SRA1 42 vlsvlnealea.crkavkkqvcddvskrlalledsWksGklslPvkkrmevlvqelkskkWdaaddihrslmvd.hvtevsqWmvGvkrlia 131 ++ l e ++ + +k+ ddvskrl+ l d+ ++ k+s P+ +++ ++q + + + h l+ e+s +m G+k l+ FUN_001190-T1 1190 TFNGLAERCKNtANNPHTKRKLDDVSKRLEALYDKLREQKMSNPILEGLHEIAQACQDRDYPRGLMAHTRLISSgSFSEISTFMPGLKSLMQ 1281 4444433332202333456778**********************************************9998752789**********9975 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.4 0.1 7.9e-05 0.075 62 145 .. 118 204 .. 106 243 .. 0.81 2 ? -1.6 0.0 1.4 1.4e+03 109 144 .. 258 295 .. 252 305 .. 0.80 3 ? -0.1 0.0 0.5 4.8e+02 112 169 .. 308 373 .. 303 387 .. 0.67 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7.9e-05 Beta-prop_DCAF12 62 akaqpasGihaielnpsktllatgGenpnslavyqlPt.ldPlclGdrkghkdwifaiawlsd..tvavsGsrdgtlalwrvdpdkl 145 ++++ ++a+++np kt l ++G + + ++ l + Pl+ G + d i+++aw + + s s g +w + +++ FUN_001190-T1 118 ESTKHTGPVQALDINPFKTSLLASGASDSEIFIWDLTNpSSPLTPGSKTLPPDNISCVAWNRQvqHILASASPCGRCVVWDLRKNEP 204 456778889**********9999999999*******76358*******************865226778999999999999877654 PP == domain 2 score: -1.6 bits; conditional E-value: 1.4 Beta-prop_DCAF12 109 kghkdwifaiawlsd..tvavsGsrdgtlalwrvdpdk 144 +gh+ i +iaw + + +s ++d + w+ ++ FUN_001190-T1 258 EGHQRGILSIAWCPQdpDLLMSCAKDNRILCWNPNTQD 295 69**********97523689999999999999877655 PP == domain 3 score: -0.1 bits; conditional E-value: 0.5 Beta-prop_DCAF12 112 kdwifaiawl..sdtvavsGsrdgtlalwrv......dpdklnasialkneaelpvyahirPkele 169 ++w f +aw + +++ s s dg ++++ + +d ++++ + +a+ p ++ir ++ + FUN_001190-T1 308 SQWSFDVAWCprNPAMICSSSFDGHVSVFSLmgggasSQDFNQQKVMSAFDADDPFSTQIRQAQQQ 373 6899*****933456889**********98733333234555555666666666666666665555 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 4.1e-05 0.039 33 98 .. 87 156 .. 75 184 .. 0.74 2 ? -1.8 0.0 1.7 1.6e+03 67 107 .. 170 211 .. 158 216 .. 0.81 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 4.1e-05 Beta-prop_VPS8 33 sliavGTshGlvLvFdseqtLklclgst...akgaeqgaVsalafnadstrlla.GyarGqilmwDlsng 98 l++ G +Gl+ +++ ++ + +++ ++++++g+V al++n +t lla G ++ +i++wDl+n FUN_001190-T1 87 GLLIGGSDNGLISIYNAQKIISGDTDDSivfESTKHTGPVQALDINPFKTSLLAsGASDSEIFIWDLTNP 156 4445566678888888877776544444222334789*********9988876538899*********97 PP == domain 2 score: -1.8 bits; conditional E-value: 1.7 Beta-prop_VPS8 67 gaVsalafnadstrllaGya.rGqilmwDlsngkllrtisda 107 +s++a n++ +++la + G+ ++wDl + + + ++sd FUN_001190-T1 170 DNISCVAWNRQVQHILASASpCGRCVVWDLRKNEPIIKVSDQ 211 5799*****99999888654279********99999888886 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.0032 3.1 335 375 .. 112 154 .. 76 159 .. 0.74 2 ? 2.4 0.2 0.08 76 2 199 .. 256 470 .. 255 475 .. 0.47 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0032 Beta-prop_SCAP 335 dscclftlqGhsGgitavyid..qtmvlasGGqdGaiclwdvl 375 d +f h+G + a+ i+ +t +lasG d i +wd+ FUN_001190-T1 112 DDSIVFESTKHTGPVQALDINpfKTSLLASGASDSEIFIWDLT 154 5667899999**********8668*****************75 PP == domain 2 score: 2.4 bits; conditional E-value: 0.08 Beta-prop_SCAP 2 llrGhlmdiecla...sdgmllvscclagqirvwdaqtgdcltvipkkglrres..sgv.lleeq.dsw.delsdaaksgeeeeldgvplrkrkr 88 +l Gh+ i +a d ll+sc +i w+ +t d+ i+ + ++ +v ++ ++ +++ +++ d++ s + g++ + ++ FUN_001190-T1 256 VLEGHQRGILSIAwcpQDPDLLMSCAKDNRILCWNPNTQDAGGEITYELPTTSQwsFDVaWCPRNpAMIcSSSFDGHVSVFSLMGGGASSQDFNQ 350 67788776666654447999******************999888876643322200222111111011112333333333333334444444444 PP Beta-prop_SCAP 89 apsrpalfsdqPdltslidtnfseqpksee.aapeprkrav..akrekeagydfgslverayeeheassvlspalsspspgaslssaeeeeae.. 178 + a +d P t++ + ++q ++++ +++p k+ +r a++ fg+ + + ++++ ++++ ++ +++++ ++++ e e++ FUN_001190-T1 351 QKVMSAFDADDPFSTQIRQAQQQQQQQQNSaPTSSPLKKPPkwLRRPCGASFSFGGKLISFGQTKDSPIAQVNISQVTTEQELVNRSYELEGAla 445 44444555566666665555555554444322233333332114445557777765444444444433333333333334444433333222211 PP Beta-prop_SCAP 179 ...s.aeksspaasaaadlessvws 199 + +s + + ++dle ++ws FUN_001190-T1 446 sgsFiQYCNSKVENSTQDLERTLWS 470 1112122233334556677777776 PP >> DUF2408 Protein of unknown function (DUF2408) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00071 0.67 70 114 .. 1187 1229 .. 1170 1238 .. 0.88 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00071 DUF2408 70 gqavlngLlddCldlvedlkakkeseekkldpklqpiYekLleik 114 q+ ngL ++C + +++ ++k+ + ++++++l+++Y+kL e k FUN_001190-T1 1187 LQETFNGLAERCKNTANNPHTKR--KLDDVSKRLEALYDKLREQK 1229 4999**************99996..667*************9866 PP >> Beta-prop_IFT122_2nd IFT122 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.00059 0.56 146 216 .. 110 188 .. 62 206 .. 0.80 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00059 Beta-prop_IFT122_2nd 146 fvdnpfpvellklkssvrclDlsasrkk.lavvdenskllvydlkt.......kellfqeenansvawNteledllcys 216 d+++ e +k++ +v++lD++ ++ la s+++++dl++ + n++ vawN++++ +l+ + FUN_001190-T1 110 DTDDSIVFESTKHTGPVQALDINPFKTSlLASGASDSEIFIWDLTNpsspltpGSKTLPPDNISCVAWNRQVQHILASA 188 4688889999*************988761577788999******98655555546677889************999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1288 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1320 (0.0516735); expected 510.9 (0.02) Passed bias filter: 803 (0.0314347); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 34 (0.00133098); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 27 [number of targets reported over threshold] # CPU time: 0.65u 0.44s 00:00:01.09 Elapsed: 00:00:00.45 # Mc/sec: 11453.61 // Query: FUN_001190-T2 [L=911] Description: FUN_001190 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-07 30.3 0.5 3.6e-05 24.2 0.2 2.9 2 TPR_Sec16 Sec16 Sec23-binding domain 0.00018 22.1 0.0 0.00052 20.6 0.0 1.7 1 Prp18 Prp18 domain 0.0012 19.0 0.0 0.0012 19.0 0.0 3.5 3 SRA1 Steroid receptor RNA activator (SRA1) ------ inclusion threshold ------ 0.13 13.3 0.0 0.48 11.5 0.0 1.9 1 DUF2408 Protein of unknown function (DUF2408) 0.31 11.3 0.6 0.74 10.1 0.6 1.6 1 Zn_ribbon_PADR1 PADR1 domain, zinc ribbon fold Domain annotation for each model (and alignments): >> TPR_Sec16 Sec16 Sec23-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.2 7e-09 3.6e-05 1 230 [. 257 454 .. 257 462 .. 0.76 2 ? -2.2 0.0 0.75 3.9e+03 248 288 .. 807 843 .. 803 848 .. 0.76 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 7e-09 TPR_Sec16 1 iqklLlkGdrekAlqlAldkklWahALliasllgkelwkevvqefvrkevkssgensesLavlyqvfaGnseeavdelvpvsaraglqeskeaeea 96 i++ Ll+G+ e+A++++l + a A+l+a + g++l +++ +++ +k+ + a l++v+++ ++v+ + + FUN_001190-T2 257 ISQALLTGNFEAAVDVCLYADRMADAFLLAIAGGPDLLARIQTRYFEKSK-------SHVARLMSVVVNRDW---RDIVE-------------SCV 329 7899*****************************************99988.......344555555555544...34454.............567 PP TPR_Sec16 97 ldkWretvalvlsnrspsdseaLle.lGklLaskgrv..eaahicfllalsqesvfgglddpsarlvllgadhvrfessfakdleailltEvyEya 189 l++Wre +a+++ +++ +aL+ lG+ L ++g+ + +c++ a + e ++v ++ +++ +++ + l E++E + FUN_001190-T2 330 LENWREALAALVTYAKAEEFTALCDlLGQRLEQEGDEhcANSMVCYICAGNVE-----------KFVSCWTK------NMPAEPSPLALQELIEKV 408 8******************88888737******98761155679*****4443...........34433333......457888999999999999 PP TPR_Sec16 190 lslspaak......ekfaglphLlayKlqhAavLaelGlvseAqkYc 230 + l++a++ +g p L++ ++A +La +G ++A Y FUN_001190-T2 409 MILKKAVErerrlfV-DSGSPILAEKLSKYAEILAAQGCLETAMGYL 454 999987776654422.2456666665567899999999999998886 PP == domain 2 score: -2.2 bits; conditional E-value: 0.75 TPR_Sec16 248 hptllaeledLserLsqspkesksswisKpsldkvwgsldk 288 h tl ++++ L+er +++ + + +K +ld v+ l++ FUN_001190-T2 807 HLTLQETFNGLAERCKNTAN----NPHTKRKLDDVSKRLEA 843 55678888999999999885....44689999999998886 PP >> Prp18 Prp18 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 1e-07 0.00052 15 76 .. 814 875 .. 807 885 .. 0.86 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 1e-07 Prp18 15 leereeeekksaegkkaaatlkqtkedlkpLlkklkkkkleedileslaeivkalqereyvk 76 ++ e+ k++a++ ++++ l + ++ l+ L +kl+++k+++ ile l+ei +a+q+r+y + FUN_001190-T2 814 FNGLAERCKNTANNPHTKRKLDDVSKRLEALYDKLREQKMSNPILEGLHEIAQACQDRDYPR 875 555566778888899999999***************************************76 PP >> SRA1 Steroid receptor RNA activator (SRA1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -7.3 4.4 5 2.6e+04 3 24 .. 557 577 .. 555 595 .. 0.61 2 ? -2.5 5.0 1 5.3e+03 5 24 .. 693 714 .. 688 749 .. 0.74 3 ! 19.0 0.0 2.4e-07 0.0012 13 131 .. 768 904 .. 756 910 .. 0.65 Alignments for each domain: == domain 1 score: -7.3 bits; conditional E-value: 5 SRA1 3 gppPasvaaPppPavlsgsvsq 24 +p P+++ +P++P+++ ++ + FUN_001190-T2 557 SPVPNPSYQPSAPHTQ-TQFYN 577 6778888888888884.33333 PP == domain 2 score: -2.5 bits; conditional E-value: 1 SRA1 5 pPasvaaPp..pPavlsgsvsq 24 pP+sv++Pp pP++++g + FUN_001190-T2 693 PPPSVTPPPpgPPPTEPGAWKD 714 5666666655677777776554 PP == domain 3 score: 19.0 bits; conditional E-value: 2.4e-07 SRA1 13 p..........pPavlsgsvsqkep........tslsvseseaeledvlsvlnealea.crkavkkqvcddvskrlalledsWksGklslPvkkrm 89 pP+ g ++ ++p + + + +l++ ++ l e ++ + +k+ ddvskrl+ l d+ ++ k+s P+ ++ FUN_001190-T2 768 MmppgggppgaPPSY--GDMPRQQPpqeppapiLKGPIPSEHLTLQETFNGLAERCKNtANNPHTKRKLDDVSKRLEALYDKLREQKMSNPILEGL 861 333334333333333..3333333333334333222222224455555555544433303344567778*************************** PP SRA1 90 evlvqelkskkWdaaddihrslmvd.hvtevsqWmvGvkrlia 131 + ++q + + + h l+ e+s +m G+k l+ FUN_001190-T2 862 HEIAQACQDRDYPRGLMAHTRLISSgSFSEISTFMPGLKSLMQ 904 *******************9998752789**********9975 PP >> DUF2408 Protein of unknown function (DUF2408) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.4e-05 0.48 70 114 .. 810 852 .. 800 861 .. 0.87 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.4e-05 DUF2408 70 gqavlngLlddCldlvedlkakkeseekkldpklqpiYekLleik 114 q+ ngL ++C + +++ ++k+ + ++++++l+++Y+kL e k FUN_001190-T2 810 LQETFNGLAERCKNTANNPHTKR--KLDDVSKRLEALYDKLREQK 852 48999*************99996..667*************9866 PP >> Zn_ribbon_PADR1 PADR1 domain, zinc ribbon fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.6 0.00014 0.74 18 33 .. 371 388 .. 363 396 .. 0.79 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00014 Zn_ribbon_PADR1 18 s..gYkCtGnvseWtkCt 33 s +Y+C Gnv+ + +C FUN_001190-T2 371 SmvCYICAGNVEKFVSCW 388 3369*************4 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (911 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1172 (0.0458798); expected 510.9 (0.02) Passed bias filter: 647 (0.0253279); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.47u 0.40s 00:00:00.87 Elapsed: 00:00:00.42 # Mc/sec: 8726.95 // Query: FUN_001191-T1 [L=375] Description: FUN_001191 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-48 165.7 20.3 2.8e-48 165.3 20.3 1.0 1 Fuseless Fuseless Domain annotation for each model (and alignments): >> Fuseless Fuseless # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 165.3 20.3 1.1e-52 2.8e-48 5 291 .. 28 315 .. 25 321 .. 0.91 Alignments for each domain: == domain 1 score: 165.3 bits; conditional E-value: 1.1e-52 Fuseless 5 lDvllsllviaPlvvayWrgtwllsdvylfpddlklsllvslligvlglliltllQeqlkeylkadkkrliyylisrlytyvfgvacvnawRgvwk 100 + +l+ + vi+P+v+++Wrgtw d+++fp+d ls ++ l++++ +++ ++l+ + lk yl++++++ yl l++y ++v v +wRg w+ FUN_001191-T1 28 ANFLIVSSVITPCVLSFWRGTWYILDLFVFPQDVVLSGWITLSTSFGIIFSVSLVENYLKAYLDRQRRKQQLYL---LLFYPLAVLSVASWRGLWM 120 6789999*********************************************************9995555555...468999************* PP Fuseless 101 lldlvtgkevltvliitvislvlLallralrnitaaPfa....illDseedyfevptlfkvskskevslyildclfsvlvvgslvvlvWrgvwvll 192 l+d +t++++++ ++ ++++++++ + +a +i+a P + i D++++ ++++ v+ s v +++++++v+v+gs v++ Wrg+w+++ FUN_001191-T1 121 LIDYYTTISFISGIVKHAVGFTIVLAAKAPSSIVAVPGYcnseINGDTSKGILQMKYAVSVNMSPFV-TRLFNAFLTVFVIGSGVICYWRGTWTIV 215 *************************************7634447889********999999988777.889************************* PP Fuseless 193 dlllfpedeetsavaslliGysvvavtfllqpllrkvs.erltglvklvvedifllisfigtvnvWrGlWnlldiyllpdkkllsawithvisfll 287 + l p+ + +s++ ++++G ++++l+ l++ + + ++ ++e +f++i +g+v W G+W l+di +lpdk++ sa+++h+++++ FUN_001191-T1 216 SVALEPKLSVKSSLITVIVGTAGCGICYCLSEVLATKKlDPSLNIGCRILEVVFVYILGLGSVCSWIGFWSLIDICILPDKPVASALLCHLVGIVC 311 *******************************999653303333355557899******************************************** PP Fuseless 288 Lvll 291 L ll FUN_001191-T1 312 LYLL 315 *998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (375 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 824 (0.0322568); expected 510.9 (0.02) Passed bias filter: 430 (0.016833); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3636.88 // Query: FUN_001192-T1 [L=510] Description: FUN_001192 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-130 434.7 1.4 6.9e-130 434.6 1.4 1.0 1 HSP70 Hsp70 protein 5.9e-11 42.3 0.2 8.9e-11 41.7 0.2 1.2 1 MreB_Mbl MreB/Mbl protein ------ inclusion threshold ------ 0.086 13.2 0.1 0.19 12.1 0.1 1.5 1 RuvC Crossover junction endodeoxyribonuclease RuvC 0.19 12.1 0.5 0.67 10.3 0.5 2.0 1 FGGY_C FGGY family of carbohydrate kinases, C-terminal dom Domain annotation for each model (and alignments): >> HSP70 Hsp70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 434.6 1.4 1.1e-133 6.9e-130 2 497 .. 5 508 .. 4 510 .] 0.94 Alignments for each domain: == domain 1 score: 434.6 bits; conditional E-value: 1.1e-133 HSP70 2 iGiDLGttnscvavmeggkievianeegnrttPsvvaftkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengka 97 +G+ LG t++ +a +e+g++e+ian+ g+r+tP++va e+ vG +Ak+ ++n+knt++ + +liG +fsd+ vq+e+++ +k+ +k +g++ FUN_001192-T1 5 LGVHLGGTSASLALCEDGRTEIIANDVGDRVTPALVACVGGEKTVGLPAKHGLIRNSKNTIARASKLIGLRFSDDAVQQEVEMCECKIIEK-DGEP 99 79****************************************************************************************9.9*** PP HSP70 98 lveveaage..kfspeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd..kernvl 189 eve++++ fsp+++ + +kl e a+a g+++++avitvP +fnd+qR a ++A++ AG+nvlR++ +p AaalaY + ++d r+vl FUN_001192-T1 100 FFEVEMNEKpiYFSPKDVLKIIFDKLLEIAQANGGNDIDEAVITVPFHFNDKQRTAAREAAEDAGFNVLRVISQPAAAALAYEIGQNDrtIRRTVL 195 *******99*99**********************************************************************9999997679**** PP HSP70 190 vyDlGggtfdvSileleeGvfevkaTngDthlGGedfDealvdylveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvded 285 vy lGg + dv +++++ G+++v+a D lGG +fDe l+++l++efkk+ + d++++++a+ +lk ae K LSs + +++ ie++ FUN_001192-T1 196 VYRLGGTSCDVTVIAVNGGMYRVVAVENDASLGGIKFDELLAQHLASEFKKQWQQDVTSNTRAMAKLKASAETCKHVLSS--RDTATCAIESLYG- 288 ********************************************************************************..7889999*****9. PP HSP70 286 gkdlseklsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsksvnpDeavaiGaAvqagvlsge.. 378 g+dl++k+sRa+fe+l+ l+++ l ++ ++l+ a+++ke+id+v+lvGGs+RiP++q+lv+e+f ke +s+npD ++a+GaA+qa +l+g FUN_001192-T1 289 GVDLNSKVSRARFESLCLSLFQQSLAAIDRVLAKARVSKENIDQVILVGGSARIPRIQQLVQEYFVdKEVLHSINPDGVLAYGAAIQASLLQGRed 384 ***************************************************************9988**************************744 PP HSP70 379 ...eevkdllllDvtpLslgietlggvmtkliernttiptkksqvfstaadnqtaveikvlqgerelakdn...kllgkfeldgippaprGvpqie 468 ++ +++ + +s+ ++ + m +i++ ipt+ +++f+taadnq++v++ v++ e e ++ +l++k l+gipp+++G+++i FUN_001192-T1 385 elnNDEDEVECT-SKTISVELDDSESFMCPIIHKYSPIPTRTTHTFTTAADNQETVRLCVYEVEEEDIPGGcgrNLVAKVVLEGIPPMAKGQANIV 479 332222222222.2333444555566799**************************************998667799******************** PP HSP70 469 VtfdidanGiltvsakdkgtgkeeeitie 497 tf++ +G l+++ +++++k++++t++ FUN_001192-T1 480 GTFHVRRDGSLHIHLVETTSQKSADMTVD 508 **********************9999986 PP >> MreB_Mbl MreB/Mbl protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.7 0.2 1.4e-14 8.9e-11 91 316 .. 135 373 .. 114 382 .. 0.79 Alignments for each domain: == domain 1 score: 41.7 bits; conditional E-value: 1.4e-14 MreB_Mbl 91 lskprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGaglpvee...psgnmvvdiGggttevavislgg.....ivtsksvrvaGd 178 ++ vi+vP + ++ +r A +eaa++aG + +i++p aAA+ ++ ++ + +v +Gg + +v+vi+++g + + + ++G FUN_001192-T1 135 NDIDEAVITVPFHFNDKQRTAAREAAEDAGFNVLRVISQPAAAALAYEIGQNDrtiRRTVLVYRLGGTSCDVTVIAVNGgmyrvVAVENDASLGGI 230 456789**************************************9988765541114678999*************97644443334567899*** PP MreB_Mbl 179 eldeaiikyi....rkkynlliGertaeeikieigsavkeeeee...kmeikGrdlvtglpkevevsseevrealkepvsaiveavkevLektppe 267 ++de + +++ +k+++ + ++t k++ ++ ++++ + + + l g+ + +vs ++ ++ + +++ + a+ +vL k+ FUN_001192-T1 231 KFDELLAQHLasefKKQWQQDVTSNTRAMAKLKASAETCKHVLSsrdTATCAIESLYGGVDLNSKVSRARFESLCLSLFQQSLAAIDRVLAKA--R 324 ****9999973333667777899999999999988877776544344667777889999*******************************986..5 PP MreB_Mbl 268 LaadivdrgivltGGgallkgldkllseet.glpvkvaedpltcvakGtg 316 +++ +d+ i l+GG+a + +++l++e + + +v + +p + a G++ FUN_001192-T1 325 VSKENIDQVI-LVGGSARIPRIQQLVQEYFvDKEVLHSINPDGVLAYGAA 373 7889899865.66************9997525667777777777777776 PP >> RuvC Crossover junction endodeoxyribonuclease RuvC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 3e-05 0.19 33 125 .. 253 351 .. 248 369 .. 0.85 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3e-05 RuvC 33 tksdplserlkavfdaveelldayepdalaieqvffaknvdsvlklaqarGvv......ilaalerelsvaeytpsqvkkavtGigkaekeqvqal 122 t++++ ++lka ++ +++l+ + ++aie+++ + + +s ++ a + +laa++r l a + +++ + + g+a +q+l FUN_001192-T1 253 TSNTRAMAKLKASAETCKHVLSSRDTATCAIESLYGGVDLNSKVSRARFESLClslfqqSLAAIDRVLAKARVSKENIDQVILVGGSARIPRIQQL 348 5677999***********************************999999988642222335889999999999999999999999999999999999 PP RuvC 123 vkr 125 v++ FUN_001192-T1 349 VQE 351 876 PP >> FGGY_C FGGY family of carbohydrate kinases, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.5 0.0001 0.67 122 194 .. 295 376 .. 195 379 .. 0.79 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0001 FGGY_C 122 elaraileglalqlrqilealeke.......eghpidtiavvGGgskndlllqllAdalg.lpvevpqt.deatalGaalla 194 + ra +e+l+l+l q a+ + ++ +id++++vGG ++ + ++ql + + + v + d a Gaa+ a FUN_001192-T1 295 KVSRARFESLCLSLFQQSLAAIDRvlakarvSKENIDQVILVGGSARIPRIQQLVQEYFVdKEVLHSINpDGVLAYGAAIQA 376 56688999999998888777755566666767888******************98776653444444443555566777666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (510 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1034 (0.0404776); expected 510.9 (0.02) Passed bias filter: 855 (0.0334703); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.38u 0.42s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 4889.11 // Query: FUN_001193-T1 [L=387] Description: FUN_001193 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-59 201.1 18.7 3e-59 201.1 18.7 1.9 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.2e-14 54.8 13.0 1.2e-14 54.8 13.0 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 6e-05 23.4 16.1 0.0014 19.0 16.1 2.4 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.15 12.1 1.0 0.98 9.5 0.1 2.4 2 Orbi_NS3 Orbivirus NS3 1.6 8.8 21.9 0.082 13.0 13.4 2.7 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.3 0.12 5.9e+02 133 166 .. 7 40 .. 1 43 [. 0.62 2 ! 201.1 18.7 5.9e-63 3e-59 1 260 [] 44 313 .. 44 313 .. 0.95 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.12 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 133 keetvClidfpeeestwevsytlllsvlgfllpl 166 ++e+ C ++++++ + ++++++++sv + ++ + FUN_001193-T1 7 STESPCNSTTSHNDVYDKRFLIVIISVYVIIIVT 40 6778888888886666666666666666665533 PP == domain 2 score: 201.1 bits; conditional E-value: 5.9e-63 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gNllV+l+i+ n++lr++tn+f+++La++Dll++ +++pf + l+ +w ge++C+++t+ ++++ +sil+l+a+siDRY+aI +pl+y + FUN_001193-T1 44 GNLLVCLAISLNRRLRKTTNYFIFSLAISDLLTASFSMPFDVQVLLQPLGWNHGEFVCNFWTFAYLIAAPTSILNLMAVSIDRYQAISNPLRYYDK 139 8*********************************************************************************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx... RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks... 189 +++rral++i+++W++++++++ + + + ++++ + +C+++++ +y +++s++ f+ p++v++v+y++i+ +r++a++ + FUN_001193-T1 140 MRPRRALAIIAAIWLYSFAFTVAGMAG--WPYYEQSVRDGMCYFNISP-------YYSVVSSAMNFIFPTMVMCVIYFKIYLIARAHAQRLVQhev 226 ************************995..55555569*******9999.......************************************99999 PP ..................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ..................kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkecese.klvetallitlllayvnsclNPiiY 260 ++kk+ +++ ka+kt++++v +f+lcw+P+ ++++++sl c+++ l++ +++ l++ay+ns+lNPi+Y FUN_001193-T1 227 pvttaatscsnedsgtmtSEKKRLKRNIKAAKTIAIIVSTFLLCWVPFTLVSTITSL---CQHCiALLPEVFNSLLVVAYMNSALNPILY 313 ***********99999998888899999*****************************...5554268899*******************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.8 13.0 2.3e-18 1.2e-14 2 256 .. 39 327 .. 37 328 .. 0.84 Alignments for each domain: == domain 1 score: 54.8 bits; conditional E-value: 2.3e-18 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltg...tqlkreeCFlliivyvfgltaqsvllLvigiDlliavkfPi 94 v + GN+l+ l++ +++Lr +++ i+ ++++dll +++++f v+ l + + C + + y++++ ++ + l+++ iD+ a++ P+ FUN_001193-T1 39 VTAICGNLLVCLAISLNRRLRKTTNYFIFSLAISDLLTASFSMPFDVQVLLQplgWNHGEFVCNFWTFAYLIAAPTSILNLMAVSIDRYQAISNPL 134 56789*****************************************98874311123344569999999999999999999*************** PP 7TM_GPCR_Srsx 95 rYrllskekYllillifpvlyssiilvlgflqrddetiiv..Capplalagkaseiftlssliinvivll.vylvliiilkkkkek.......... 177 rY + + l+ ++ lys +++v g+ + + v + + +++ s + + +++i+ ++v++ +y+ +++i++ + ++ FUN_001193-T1 135 RYYDKMRPRRALAIIAAIWLYSFAFTVAGMAGWPYYEQSVrdGMCYFNISPYYSVVSSAMNFIFPTMVMCvIYFKIYLIARAHAQRlvqhevpvtt 230 **998888888888889999999999999876554433331133344444455566667777777776651677777777877777********** PP 7TM_GPCR_Srsx 178 ..................kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafre 255 + ++ k k +++ v+ f+++W+ t+++t++ ++ +++ ++ + +++ ++++ n + + + ++e+r+af++ FUN_001193-T1 231 aatscsnedsgtmtsekkRLKRNIKAAKTIAIIVSTFLLCWVPFTLVSTITSLCQHCIALLPEVFNSLLVVAYMNSALNPILYSFLNREFRDAFKK 326 *************9987666777788899*****************************************************************99 PP 7TM_GPCR_Srsx 256 l 256 l FUN_001193-T1 327 L 327 7 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 16.1 2.7e-07 0.0014 3 277 .. 36 328 .. 31 331 .. 0.75 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 2.7e-07 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesav...llamavdrfva 95 ++ + ++ Gnl + i ++ l + +f+ la+ dl + ++P + ++l + ++ f+ ++ + ++ l+a+++dr+ a FUN_001193-T1 36 IIIVTAICGNLLVCLAISLNRRLRKTTNYFIFSLAISDLLTASFSMPFDVQVLLQPLGWNHG--EFVCNFWTFAYLIAAPTSilnLMAVSIDRYQA 129 44455688********************************9999***988887755443222..244444444555554443112678999***** PP 7tm_4 96 iysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsygli 191 i +plry + + ++ i + +++ s+++ + + +++ +++ c + + s + +n i+ +v++ + + + li+ ++++ FUN_001193-T1 130 ISNPLRYYDKMRPRRALAIIAAIWLYSFAFTVA---GMAGWPYYE-QSVRDGMCYFNISPYYSVVSSAMNFIFPT-MVMCVIYFKIYLIARAHAQR 220 *******99999888889999999999996543...456788885.678999999999999************98.78899999999998887764 PP 7tm_4 192 l..rtv..l............giasreerk....kalntcgshvcavlafyvPmiglsvvhrfgkkvsrllqvllanlyll..fPPvlnPivysvk 265 l + v +++s ++r+ ka +t + v + l+ +vP +s + + ++ ll ++ l ++ + lnPi+ys FUN_001193-T1 221 LvqHEVpvTtaatscsnedsgTMTSEKKRLkrniKAAKTIAIIVSTFLLCWVPFTLVSTITSLCQHCIALLPEVFNSLLVVayMNSALNPILYSFL 316 422544221111111222221244555665223357888888999999******************999998888877765336789********* PP 7tm_4 266 tkeirdavvkil 277 +e rda +k+l FUN_001193-T1 317 NREFRDAFKKLL 328 *******99987 PP >> Orbi_NS3 Orbivirus NS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.1 5.2e+02 70 136 .. 136 205 .. 102 225 .. 0.72 2 ? 9.5 0.1 0.00019 0.98 67 127 .. 243 304 .. 235 332 .. 0.77 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.1 Orbi_NS3 70 elrklkrkrlllklvelilavlalltslvmlvkelsetvekns...evpawlkslsavvsvinllatvvl 136 + k++ +r+l ++ + l +a ++ ++ +++v ++ +++ +++ +s+++++i + + + FUN_001193-T1 136 YYDKMRPRRALAIIAAIWLYSFAFTVAGMAGWPYYEQSVRDGMcyfNISPYYSVVSSAMNFIFPTMVMCV 205 5667777877777778888888888888888888888887733445677776667776666644443333 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00019 Orbi_NS3 67 lekelrklkrkrlllklvelilavlalltslvmlvkelsetvek.nsevpawlkslsavvsv 127 + +e ++lkr + k++ +i+++++l ++ +lv+++++ ++ + +p+ ++sl +v + FUN_001193-T1 243 MTSEKKRLKRNIKAAKTIAIIVSTFLLCWVPFTLVSTITSLCQHcIALLPEVFNSLLVVAYM 304 77899*********************************999987422555555555444444 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 13.4 1.6e-05 0.082 8 191 .. 42 217 .. 35 230 .. 0.71 2 ? 0.5 0.6 0.1 5.2e+02 40 86 .. 261 311 .. 252 331 .. 0.63 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.6e-05 7TM_GPCR_Srx 8 lvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsellkellnshliglialglYei....splsqllialNRfcavffp 99 ++ Nllv +ai + +l++ ++ +s ais++++ ++ + + +++l ++l++++ + +++ ++ ++Y+i s+l + ++++R a+ p FUN_001193-T1 42 ICGNLLVCLAISLNRRLRKTTNYFIFSLAISDLLTASFSMPF--DVQVLLQPLGWNHGE-FVCNFW-TFAYLIaaptSILNLMAVSIDRYQAISNP 133 667999999999999999999***********9887766555..556666666666622.344443.334443111145555679*********** PP 7TM_GPCR_Srx 100 lkyekifsiknTkiiiviiwivslifitvlylpegCkllynpetltwsfeeteccktiswyldfllililviitlvlnlltaiklilskkks 191 l+y + + + ii++iw++s++ tv ++ + +y+ +++ + c is y +++ +++ +i+ +++ ++++k++l + + FUN_001193-T1 134 LRYYDKMRPRRALAIIAAIWLYSFA-FTVAGMAG--WPYYE-QSV----RDGMCYFNISPYYSVVSSAMNFIFPTMVMCVIYFKIYLIARAH 217 *************************.55555444..45555.443....3566777777777777777777777777777777777544443 PP == domain 2 score: 0.5 bits; conditional E-value: 0.1 7TM_GPCR_Srx 40 aiilliflfyvvPmtllqsell..kellnsh..liglialglYeisplsql 86 aii+++fl++ vP tl+++ + ++ + ++ +++++Y+ s l + FUN_001193-T1 261 AIIVSTFLLCWVPFTLVSTITSlcQHCIALLpeVFNSLLVVAYMNSALNPI 311 577888888888888876533222222221122555555555555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (387 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1296 (0.050734); expected 510.9 (0.02) Passed bias filter: 610 (0.0238794); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3815.09 // Query: FUN_001194-T1 [L=550] Description: FUN_001194 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.06 13.8 0.1 3.6 8.1 0.1 2.7 2 Tox-GHH GHH signature containing HNH/Endo VII superfamily n Domain annotation for each model (and alignments): >> Tox-GHH GHH signature containing HNH/Endo VII superfamily nuclease toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.1 0.00014 3.6 4 28 .. 18 42 .. 17 57 .. 0.76 2 ? 2.6 0.0 0.0075 1.9e+02 37 70 .. 176 209 .. 162 215 .. 0.81 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.00014 Tox-GHH 4 krllehakkravreaWerErqllra 28 +r+l+ ++ ++ +W +Er + + FUN_001194-T1 18 TRVLRTHRRNSMEHFWLQERVRTID 42 69******************98765 PP == domain 2 score: 2.6 bits; conditional E-value: 0.0075 Tox-GHH 37 teeekeeLlstgkvsgYdgeyihsveqypeLadd 70 + + + l+ g+v +++ y+ s+++ eLa + FUN_001194-T1 176 SYRKITPPLRPGSVRNFKDVYQESLDKNDELASS 209 55555555788********************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (550 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1019 (0.0398904); expected 510.9 (0.02) Passed bias filter: 424 (0.0165982); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 5470.02 // Query: FUN_001195-T1 [L=524] Description: FUN_001195 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (524 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1728 (0.0676453); expected 510.9 (0.02) Passed bias filter: 600 (0.023488); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5021.89 // Query: FUN_001196-T1 [L=303] Description: FUN_001196 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-46 157.6 0.3 9.3e-46 157.2 0.3 1.2 1 Metallophos Calcineurin-like phosphoesterase Domain annotation for each model (and alignments): >> Metallophos Calcineurin-like phosphoesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 157.2 0.3 3.6e-50 9.3e-46 2 192 .. 45 237 .. 44 239 .. 0.95 Alignments for each domain: == domain 1 score: 157.2 bits; conditional E-value: 3.6e-50 Metallophos 2 rilvigDlHgegqfddllellekl..rpeekpdlvliaGDlvdrg..sletevlellallvky.ipvflvrGNHd.........fydeclrkygel 83 +++v+gD+H gqf+dl+el++ +p+ + ++++ GD+vdrg slet + +ll l++k +++ l+rGNH+ fydec+ kyg+ FUN_001196-T1 45 PVTVCGDIH--GQFYDLEELFNTGgqVPD-TSYVFM--GDFVDRGyfSLET-FTRLLTLKAKWpDRITLLRGNHEsrqitqvygFYDECQAKYGN- 133 89*******..**********99964444.779999..*************.777777777778******************************9. PP Metallophos 84 nllarpwkafvevfnllplaaliggkillvhGgls.elvtlddirgldrprevpeeg...dlllsdarkkadwvivlgHaplyrgasylfgpealr 175 a+ w+++++vf+ll++aa+i+g+il+vhGgls ++ tld+ir +dr+ e+p++g dl +sd + v ++a ++rga++lfg++++ FUN_001196-T1 134 ---ANAWRYCCKVFDLLTVAAVIDGQILCVHGGLSpDIRTLDQIRTIDRNMEIPHKGafcDLVWSD------PEDVDTWAISPRGAGWLFGSKVTN 220 ...99*************************************************************......************************ PP Metallophos 176 kllkrngvdlvlsGHtH 192 +++ n+++l++++H+ FUN_001196-T1 221 EFVHINNLKLICRAHQL 237 ***************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (303 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 651 (0.0254844); expected 510.9 (0.02) Passed bias filter: 543 (0.0212566); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3038.70 // Query: FUN_001197-T1 [L=274] Description: FUN_001197 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.3e-13 49.5 0.1 1.2e-12 48.8 0.1 1.5 1 MRP-S28 Mitochondrial ribosomal subunit protein Domain annotation for each model (and alignments): >> MRP-S28 Mitochondrial ribosomal subunit protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.8 0.1 4.8e-17 1.2e-12 22 93 .. 140 211 .. 119 247 .. 0.91 Alignments for each domain: == domain 1 score: 48.8 bits; conditional E-value: 4.8e-17 MRP-S28 22 ehpaerKvvlevkvadLgleekqqhklklLagprynpetdiiklssekfeeaaqNkrylsdilekLlkeakd 93 hp +rKv l+v ++dL l++++++k+ L+gpryn++td + + ++ ++++qNk y++ +l+ L +ea + FUN_001197-T1 140 YHPGSRKVKLQVYLKDLVLDDHARKKMISLVGPRYNADTDELTIVADRCPTRKQNKDYAMYLLTVLYHEAWK 211 3999***************************************************************99965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (274 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 944 (0.0369544); expected 510.9 (0.02) Passed bias filter: 574 (0.0224702); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 2647.76 // Query: FUN_001198-T1 [L=381] Description: FUN_001198 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-32 112.6 15.4 1.7e-16 60.5 1.9 3.2 3 Beta-prop_THOC3 THOC3 beta-propeller domain 9.9e-30 104.1 5.5 1.4e-16 61.3 4.2 2.3 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1e-29 104.3 14.4 3.1e-23 83.0 9.3 2.7 2 Beta-prop_WDR5 WDR5 beta-propeller domain 6.1e-24 85.0 3.2 1.9e-16 60.5 1.0 2.4 2 WD40_Prp19 Prp19 WD40 domain 4.9e-23 82.4 7.4 3.3e-14 53.3 4.0 2.7 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 8.4e-21 74.0 26.5 9.1e-05 23.3 0.2 7.5 7 WD40 WD domain, G-beta repeat 1.7e-18 67.4 5.7 5e-15 56.1 0.5 2.5 2 Beta-prop_EML_2 Echinoderm microtubule-associated 5.2e-18 65.7 3.4 5.2e-18 65.7 3.4 1.9 2 WD40_WDHD1_1st WDHD1 first WD40 domain 1.3e-15 58.0 1.6 2.4e-08 34.1 0.5 2.7 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 1.4e-15 57.6 0.6 4.3e-09 36.3 1.0 2.6 2 WDR55 WDR55 2.2e-15 57.0 11.2 9.7e-08 32.0 0.7 3.2 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 8.7e-12 45.5 1.1 0.00094 19.2 1.3 3.7 4 Beta-prop_RIG_2nd RIG second beta-propeller 5.6e-11 42.9 0.4 1.4e-07 31.7 0.0 2.4 3 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 1e-10 41.7 0.3 3.2e-10 40.2 0.3 2.2 1 EIF3I EIF3I 1.8e-10 40.8 3.4 2.8e-06 27.0 2.6 2.3 2 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 2.5e-10 40.5 0.3 4.5e-06 26.6 0.0 3.0 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 4.1e-10 39.6 4.3 3.4e-08 33.3 0.6 3.0 3 Beta-prop_SPT8 SPT8 beta propeller 8.7e-10 38.8 8.5 7.8e-08 32.4 3.7 3.1 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 2e-09 37.4 8.5 7.5e-07 28.9 5.3 3.3 3 WD40_Gbeta G protein beta WD-40 repeat protei 3.2e-09 36.7 10.0 0.007 15.9 0.1 3.9 4 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 1.2e-08 35.3 2.5 0.00095 19.2 0.4 2.6 3 Beta-prop_EIPR1 EIPR1 beta-propeller 9.7e-08 32.2 5.4 0.00018 21.4 1.0 3.0 3 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 4e-07 30.1 2.3 0.0018 18.1 0.1 3.2 3 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 6.1e-07 29.1 0.2 9.5e-07 28.5 0.2 1.3 1 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 1.1e-05 25.5 5.1 0.1 12.6 0.1 2.9 3 Beta-prop_EML Echinoderm microtubule-associated 1.2e-05 25.9 2.3 0.034 14.9 0.0 4.1 4 ANAPC4_WD40 Anaphase-promoting complex subunit 2e-05 24.0 2.1 0.0026 17.0 0.0 2.7 3 Beta-prop_IFT140_1st IFT140 first beta-propeller 0.00026 21.4 4.3 0.019 15.5 0.8 2.9 3 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 0.00038 20.4 3.6 0.02 14.8 1.2 2.5 3 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 0.0004 19.8 2.5 0.0019 17.6 2.5 2.1 2 NBCH_WD40 Neurobeachin beta propeller domain 0.00051 19.6 0.0 1.1 8.7 0.0 3.6 4 Beta-prop_VPS8 Vps8 beta-propeller 0.0016 17.6 1.7 0.18 10.8 0.1 3.1 3 Beta-prop_RIG_1st RIG first beta-propeller 0.0035 17.0 0.0 0.016 14.8 0.0 1.9 2 Beta-prop_NOL10_N Nucleolar protein 10-like, N-termi 0.0075 15.8 0.1 0.029 13.8 0.0 1.8 2 MIOS_WD40 MIOS, WD40 repeat ------ inclusion threshold ------ 0.021 14.6 0.0 7.2 6.2 0.0 2.4 2 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller Domain annotation for each model (and alignments): >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.2 1.3 1.2e-11 8.9e-09 12 85 .. 70 144 .. 60 146 .. 0.72 2 ! 60.5 1.9 2.4e-19 1.7e-16 1 114 [. 105 221 .. 105 223 .. 0.90 3 ! 40.3 0.2 3.5e-13 2.5e-10 6 120 .. 198 315 .. 193 366 .. 0.82 Alignments for each domain: == domain 1 score: 35.2 bits; conditional E-value: 1.2e-11 Beta-prop_THOC3 12 adGkrLasgsaDktvrvwnleks..klsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatv 85 d +rL+ gs+ +v +w l s +l++ ++l+ h+++V++++++ ++ ++++s+D++++ Wd++++k++++ FUN_001198-T1 70 IDSRRLVLGSDSGSVDIWCLSGSfqNLENMASLTDHDNTVSSVSVDCIKS-KIVSGSWDRSIKEWDIEQEKCVRSY 144 57788888888888888887765324444567888888888888888765.5788888888888888888888776 PP == domain 2 score: 60.5 bits; conditional E-value: 2.4e-19 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgen..i 92 h+++v+sv+ + ++++sgs D++++ w++e++k+++ ++kgh+d V + +s ++dl++++s+D ++ lWd+r+ k +++++ ++ + i FUN_001198-T1 105 HDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVR--SYKGHSDMVWSAIYSRAEQDLFVSVSQDGCIILWDARAPKIATKLTDSSYYasI 196 8999********************************99..6*************************************9999998876654222 PP Beta-prop_THOC3 93 ..nlawsp.dGktiavgskddtvsl 114 ++ wsp d + +avg +d v l FUN_001198-T1 197 phCVDWSPlDHHLLAVGYEDGSVCL 221 32799***899999***99988866 PP == domain 3 score: 40.3 bits; conditional E-value: 3.5e-13 Beta-prop_THOC3 6 hsvawsa.dGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgenin.laws 97 h+v+ws+ d + La g +D +v++ n+++ k+ ++ h+++V++la+sp +p+ lat+s+D v + d+ + ++ + ++e + laws FUN_001198-T1 198 HCVDWSPlDHHLLAVGYEDGSVCLCNIQNPKQP-VLTYCHHERAVNKLAFSPRSPEWLATVSDDMWVHVQDCLNDTTVLRSDEHSEVVRgLAWS 290 89****845667788899**********99765.579999************************************99999999999966**** PP Beta-prop_THOC3 98 pdGktiavgskddtvs..lidvrtg 120 p t+ ++ +++ +d++ + FUN_001198-T1 291 PVDDTLYTSGWGQQIFshAFDCSGQ 315 *988888877666653124555555 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.3 4.2 1.9e-19 1.4e-16 40 152 .. 71 188 .. 38 196 .. 0.87 2 ! 47.7 0.0 2.7e-15 1.9e-12 11 132 .. 173 300 .. 173 330 .. 0.87 Alignments for each domain: == domain 1 score: 61.3 bits; conditional E-value: 1.9e-19 Beta-prop_WDR3_1st 40 dgkklavGyadgsirlwdl....esgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvafle.ek 125 d+++l G++ gs+ +w l ++ e ++++ H ++v++++ d +s+++sGs D +i wD+ +e+++ kgH+d v+s+ +++ e+ FUN_001198-T1 71 DSRRLVLGSDSGSVDIWCLsgsfQNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRaEQ 161 678899***********8844446667789********************************************************97367 PP Beta-prop_WDR3_1st 126 kvlvssSkDtliklWdletqhcvktlv 152 ++ vs S+D +i lWd + + ++l+ FUN_001198-T1 162 DLFVSVSQDGCIILWDARAPKIATKLT 188 899*************98877766665 PP == domain 2 score: 47.7 bits; conditional E-value: 2.7e-15 Beta-prop_WDR3_1st 11 vlvWdlkkgekvatlegek...sevtalaasp.dgkklavGyadgsirlwdles.gelevtfngHksavtalafdkdg.srLasGskDtdi 95 +++Wd + + +++l++++ s ++ sp d++ lavGy+dgs+ l ++++ ++ +t+ H++av+ laf+++ + La+ s D + FUN_001198-T1 173 IILWDARAPKIATKLTDSSyyaSIPHCVDWSPlDHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWV 263 689*******99999876522144589999*9567789**************984556789999***********876367********** PP Beta-prop_WDR3_1st 96 ivwDvvaeaglfrLkgHkdqvtsvafleekkvlvssS 132 +v D ++++ + r H++ v +a+++ +++l +s+ FUN_001198-T1 264 HVQDCLNDTTVLRSDEHSEVVRGLAWSPVDDTLYTSG 300 ****************************999999886 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.0 9.3 4.2e-26 3.1e-23 46 216 .. 59 237 .. 7 238 .. 0.81 2 ! 31.8 0.4 1.7e-10 1.2e-07 11 114 .. 199 305 .. 198 337 .. 0.86 Alignments for each domain: == domain 1 score: 83.0 bits; conditional E-value: 4.2e-26 Beta-prop_WDR5 46 ghkkGisdvawssdskllasaSDDktvriwdve....tgkllktlkgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsdpvs 136 + ++G d++w ds+ l+ +SD +v iw ++ + + + l+ H n v +v+ + ++ +vSGs D +++ Wd++++kc+++ ++Hsd v FUN_001198-T1 59 STESGTTDIKWI-DSRRLVLGSDSGSVDIWCLSgsfqNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVW 152 467899*****7.6999*************8875554667999***************************************************9 PP Beta-prop_WDR5 137 avdfnrdgt.livsssyDgliriwdtetgqclktlveddnp..pvsfvkFspngkyiLastl.dstirLwdyek.ekvvktYkgh 216 + ++r + l+vs s Dg+i +wd++ ++ +l++++ +v +sp ++++La d ++ L+++++ ++ v tY h FUN_001198-T1 153 SAIYSRAEQdLFVSVSQDGCIILWDARAPKIATKLTDSSYYasIPHCVDWSPLDHHLLAVGYeDGSVCLCNIQNpKQPVLTYCHH 237 9999886554*************************987443336689**********98755499*******9945577777655 PP == domain 2 score: 31.8 bits; conditional E-value: 1.7e-10 Beta-prop_WDR5 11 svkfsp.dgkllasasaDktikiwdvee.gklektleghkkGisdvawssds.kllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkg 102 +v sp d +lla +D+++ + ++++ + + t h++ ++++a+s+ s ++la+ SDD+ v++ d+ + +++ ++H+++v +a++p FUN_001198-T1 199 CVDWSPlDHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHVQDCLNDTTVLRSDEHSEVVRGLAWSPVD 293 56677757899**************9873568899999************98579**************************************99 PP Beta-prop_WDR5 103 nllvSGsfDetv 114 ++l +++ +++ FUN_001198-T1 294 DTLYTSGWGQQI 305 999888877766 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.5 1.0 2.6e-19 1.9e-16 37 186 .. 94 247 .. 57 247 .. 0.86 2 ! 32.4 0.0 9e-11 6.5e-08 10 134 .. 198 325 .. 191 341 .. 0.82 Alignments for each domain: == domain 1 score: 60.5 bits; conditional E-value: 2.6e-19 WD40_Prp19 37 esekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaev.tslsvhptgdylvsaskDgtwalhdletgktllkvkd 131 ++ + +a+l+ h +v++v + ++ +vs+s D++++ w+ e+++++ +k h++ v +++ + +d++vs+s+Dg++ l+d+++ k+ +k++d FUN_001198-T1 94 QNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVwSAIYSRAEQDLFVSVSQDGCIILWDARAPKIATKLTD 189 46677899************************************************99678999******************************99 PP WD40_Prp19 132 eeskeai.tsaqfHP.DGlllgtGtkdgtvkiWDiks.qknvasleghsgavtslaFS 186 + ++i +++ + P D +ll++G +dg+v + +i++ ++ v + h+ av++laFS FUN_001198-T1 190 SSYYASIpHCVDWSPlDHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFS 247 888666669*****99*******************9945678888999*********9 PP == domain 2 score: 32.4 bits; conditional E-value: 9e-11 WD40_Prp19 10 laldlnpsdknlvltGGaDknvvlfdres.ekvlatlkghtkkvtavafhpse.dvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptg 103 +++d +p d++l++ G +D++v+l + ++ ++ + t+ h+++v+++af+p++ + l + s+D v+v ++ +++t+ ++h++ v++l+ p+ FUN_001198-T1 198 HCVDWSPLDHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHVQDCLNDTTVLRSDEHSEVVRGLAWSPVD 293 69************************77516678889999**********97737899************************************** PP WD40_Prp19 104 dylvsaskDgtwalhdle.tgktllkvkdees 134 d l +++ +++ h ++ +g+ l+v+ +s FUN_001198-T1 294 DTLYTSGWGQQIFSHAFDcSGQSDLNVEASKS 325 **999987777666554422333334544444 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.3 4.0 4.6e-17 3.3e-14 50 209 .. 60 224 .. 36 225 .. 0.80 2 ! 31.0 0.1 3e-10 2.2e-07 108 199 .. 212 303 .. 212 339 .. 0.82 Alignments for each domain: == domain 1 score: 53.3 bits; conditional E-value: 4.6e-17 WD40_CDC20-Fz 50 esdyvtsvkwsedgelLavGtssgevelw....dvekkkklrtleghssrvgalaw..nenllssGsrdgkilhhDvrtkelevvktlkahkqevc 139 +++ t +kw++ ++ L++G++sg+v +w + ++ + + +l+ h+++v+++++ ++ ++sGs d++i +D+ +++ +v+++k+h++ v FUN_001198-T1 60 TESGTTDIKWID-SRRLVLGSDSGSVDIWclsgSFQNLENMASLTDHDNTVSSVSVdcIKSKIVSGSWDRSIKEWDIEQEK--CVRSYKGHSDMVW 152 4567899****8.67889***********65555666677888899******9999334678*****************96..789*********9 PP WD40_CDC20-Fz 140 glkwspd.grllAsGgndntvkiwdlrsls...pllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwnt 209 + +s+ ++l+ s ++d+++ +wd+r + +l + + +++W+p +++lLa G ++D++++l n+ FUN_001198-T1 153 SAIYSRAeQDLFVSVSQDGCIILWDARAPKiatKLTDSSYYASIPHCVDWSPLDHHLLAVG--YEDGSVCLCNI 224 98887751678999************97761113444445778889*************96..68888888876 PP == domain 2 score: 31.0 bits; conditional E-value: 3e-10 WD40_CDC20-Fz 108 sGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdg.rllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGt 199 +G +dg++ +++ ++ v t+ +h++ v l++sp + + lA+ + d v++ d + + +l+ +eh+ v+ laW+p + +l +G G FUN_001198-T1 212 VGYEDGSVCLCNIQNPKQ-PVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHVQDCLNDTTVLRSDEHSEVVRGLAWSPVDDTLYTSGWGQ 303 588899999999999974.56889999999999999997648899999999999999999999999999999999999999988888877665 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.29 2.1e+02 6 30 .. 7 28 .. 3 43 .. 0.72 2 ? 2.7 1.5 0.42 3.1e+02 14 38 .. 64 87 .. 53 88 .. 0.85 3 ! 21.8 1.2 3.7e-07 0.00027 4 39 .] 99 134 .. 96 134 .. 0.92 4 ! 23.3 0.2 1.2e-07 9.1e-05 2 39 .] 139 177 .. 138 177 .. 0.83 5 ! 10.7 0.3 0.0013 0.92 15 37 .. 198 221 .. 189 223 .. 0.85 6 ! 14.5 0.0 8.1e-05 0.059 2 37 .. 229 265 .. 228 267 .. 0.86 7 ! 10.8 0.0 0.0011 0.82 8 34 .. 278 304 .. 272 306 .. 0.82 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.29 WD40 6 tlkgHtsgVtslafspdgsllasgs 30 +l++H V ++++ dg+l +++s FUN_001198-T1 7 ELHAH---VDAIDIEEDGTLAVASS 28 68889...9***********76655 PP == domain 2 score: 2.7 bits; conditional E-value: 0.42 WD40 14 VtslafspdgsllasgsdDgtvklW 38 t++++ ++ +l++ gsd g+v +W FUN_001198-T1 64 TTDIKWIDSRRLVL-GSDSGSVDIW 87 58899999999999.*******999 PP == domain 3 score: 21.8 bits; conditional E-value: 3.7e-07 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +++l+ H+++V+s++ + s ++sgs+D+++k Wd FUN_001198-T1 99 MASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWD 134 67899**999****99999999*************9 PP == domain 4 score: 23.3 bits; conditional E-value: 1.2e-07 WD40 2 kllrtlkgHtsgVtslafspdgsll.asgsdDgtvklWd 39 k++r++kgH++ V+s +s + l +s s Dg++ lWd FUN_001198-T1 139 KCVRSYKGHSDMVWSAIYSRAEQDLfVSVSQDGCIILWD 177 8********777*9999766666651677*********9 PP == domain 5 score: 10.7 bits; conditional E-value: 0.0013 WD40 15 tslafspdgslla.sgsdDgtvkl 37 ++++sp +++l+ +g +Dg+v+l FUN_001198-T1 198 HCVDWSPLDHHLLaVGYEDGSVCL 221 69*********643889*****98 PP == domain 6 score: 14.5 bits; conditional E-value: 8.1e-05 WD40 2 kllrtlkgHtsgVtslafspdgsl.lasgsdDgtvkl 37 +++ t+ H+ +V+ lafsp ++ la+ sdD v++ FUN_001198-T1 229 QPVLTYCHHERAVNKLAFSPRSPEwLATVSDDMWVHV 265 689999999999*****999888879999*9998876 PP == domain 7 score: 10.8 bits; conditional E-value: 0.0011 WD40 8 kgHtsgVtslafspdgsllasgsdDgt 34 + H++ V++la+sp ++ l+++++ FUN_001198-T1 278 DEHSEVVRGLAWSPVDDTLYTSGWGQQ 304 479666****************98765 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.7 6.8e-05 0.049 38 171 .. 8 153 .. 3 157 .. 0.72 2 ! 56.1 0.5 6.9e-18 5e-15 7 163 .. 158 319 .. 151 369 .. 0.75 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 6.8e-05 Beta-prop_EML_2 38 lekearsvafspdgkllavGl......kdGsvlvldaet....leevvevkdrkeaisdikfspdgklLavgshdnkiylYdvsk...kykkvg 118 l++ + ++++++dg+l ++ + +Gs+ +++ + ++ + ++++ +dik+ + ++ L++gs ++++++ +s ++++++ FUN_001198-T1 8 LHAHVDAIDIEEDGTLAVASSaltgrtWNGSLWLFKDRAkapdVQYCSAGCSTESGTTDIKWID-SRRLVLGSDSGSVDIWCLSGsfqNLENMA 100 5666777777777776555544444445777777654430000344445566788899999975.56678899999999999986222566778 PP Beta-prop_EML_2 119 klkghssfithlDwsedskylqsnsgdyellfwdaktgkqvtsasalkdveWa 171 +l++h++++ ++ + + s s d ++ wd+++ k v+s + d+ W+ FUN_001198-T1 101 SLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWS 153 88999999999999999999999999999999999999999999999999997 PP == domain 2 score: 56.1 bits; conditional E-value: 6.9e-18 Beta-prop_EML_2 7 hpsepqfvTagdDktvrlWdlekkklvakv....klekearsvafsp.dgkllavGlkdGsvlvldaet.leevvevkdrkeaisdikfspdg. 93 +++ fv++++D+ ++lWd+++ k+ k+ + + ++v++sp d++llavG++dGsv++ + ++ + v + ++++a+++++fsp + FUN_001198-T1 158 RAEQDLFVSVSQDGCIILWDARAPKIATKLtdssYYASIPHCVDWSPlDHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFSPRSp 251 567899***************9987776651110344456******9455679*************99824569999**************655 PP Beta-prop_EML_2 94 klLavgshdnkiylYdvskkykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkqvtsas 163 ++La s d +++ d+ ++ + v + ++hs+ ++ l ws +++l ++ g ++++f +a +++ ++ + FUN_001198-T1 252 EWLATVSDDMWVHVQDCLNDTT-VLRSDEHSEVVRGLAWSPVDDTLYTS-GWGQQIFSHAFDCSGQSDLN 319 9***************988766.77889************999999765.78888888887776555543 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 1.8 1.3e+03 86 105 .. 9 28 .. 6 31 .. 0.84 2 ! 65.7 3.4 7.1e-21 5.2e-18 55 281 .. 71 297 .. 37 305 .. 0.86 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.8 WD40_WDHD1_1st 86 tapvthialskdgkllaags 105 +a+v +i++++dg+l +a+s FUN_001198-T1 9 HAHVDAIDIEEDGTLAVASS 28 68999********8888877 PP == domain 2 score: 65.7 bits; conditional E-value: 7.1e-21 WD40_WDHD1_1st 55 ksdklvvatddntvq....lytfpegekdgiltrftapvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvald.pkgeyla 144 s++lv ++d+++v+ + +f++ e+ lt +v +++++ ++++++gs D +ik ++e+++ + +++gh++ v s ++ +++ + + FUN_001198-T1 71 DSRRLVLGSDSGSVDiwclSGSFQNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSrAEQDLFV 165 67899********994443458899999999**************************************************9966651677899* PP WD40_WDHD1_1st 145 SsscDGtvkiWdieskecvktlkvlpksndfsaskslcrlawepksgkllavPvek.evklyerdtweeafklsknklsedisivafSpcG.kyl 237 S s DG + +Wd + +++++l+ + ++ ++w+p + +llav e+ +v l + ++ ++ l+ ++++ ++ +afSp ++l FUN_001198-T1 166 SVSQDGCIILWDARAPKIATKLTD-----SSYYASIPHCVDWSPLDHHLLAVGYEDgSVCLCNIQNPKQ-PVLTYCHHERAVNKLAFSPRSpEWL 254 **************9999877554.....3344566789**************8874799999998875.578889999**********9879** PP WD40_WDHD1_1st 238 aaatvdgeilvWdvatkeliervkhekklaitslaWnpkeneLa 281 a+ + d + v d +++ + r + e++ + +laW+p +++L FUN_001198-T1 255 ATVSDDMWVHVQDCLNDTTVLRSD-EHSEVVRGLAWSPVDDTLY 297 *****************9999976.55789********998875 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.5 3.3e-11 2.4e-08 128 238 .. 76 189 .. 72 192 .. 0.85 2 ! 17.6 0.1 3.5e-06 0.0025 226 294 .. 134 207 .. 133 209 .. 0.80 3 ! 21.0 0.0 3.1e-07 0.00023 209 299 .. 206 299 .. 200 306 .. 0.87 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 3.3e-11 Beta-prop_WDR36-Utp21_2nd 128 viGyssGhvdrfNlqSglhR.gsygkekahkkavrGvavdalnqvvitagadkklkfwkfkskklletlkleasi..sklvlhr 208 v+G++sG+vd + l ++ +++++ + h+++v+ v+vd +++++++++ d+ +k w+++++k +++ k ++ + s++ + FUN_001198-T1 76 VLGSDSGSVDIWCLSGSFQNlENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMvwSAIYSRA 159 89**********9965554424567889****************************************9977665115667788 PP Beta-prop_WDR36-Utp21_2nd 209 essllavalddfsilvvDidtrrvvRkfsg 238 e +l + +d +i++ D + +++ k+++ FUN_001198-T1 160 EQDLFVSVSQDGCIILWDARAPKIATKLTD 189 9999999999999*****999999888765 PP == domain 2 score: 17.6 bits; conditional E-value: 3.5e-06 Beta-prop_WDR36-Utp21_2nd 226 DidtrrvvRkfsghknritDltfspdar.WlitasmDstirtwdlps....gkliDvflvesaatslslsptgd 294 Di+++++vR+++gh+ + +++s + +++ s D +i wd + +kl D s++ ++ sp ++ FUN_001198-T1 134 DIEQEKCVRSYKGHSDMVWSAIYSRAEQdLFVSVSQDGCIILWDARApkiaTKLTDSSYYASIPHCVDWSPLDH 207 9**********************98655166999**********875222256778888888888888888776 PP == domain 3 score: 21.0 bits; conditional E-value: 3.1e-07 Beta-prop_WDR36-Utp21_2nd 209 essllavalddfsilvvDidt.rrvvRkfsghknritDltfspda.rWlitasmDstirtwdlps.gkliDvflvesaatslsl 289 + llav ++d s+++ i+ ++ v ++ h+ ++ l+fsp + Wl t s D +++ d + ++++ + ++++ l+ FUN_001198-T1 206 DHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHVQDCLNdTTVLRSDEHSEVVRGLAW 289 5689***************863789*****************98758***************765155666777889999**** PP Beta-prop_WDR36-Utp21_2nd 290 sptgdfLata 299 sp +d L t+ FUN_001198-T1 290 SPVDDTLYTS 299 ******9987 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.3 1.0 5.9e-12 4.3e-09 19 136 .. 73 190 .. 57 196 .. 0.85 2 ! 18.0 0.0 2.3e-06 0.0017 19 113 .. 207 300 .. 195 308 .. 0.77 Alignments for each domain: == domain 1 score: 36.3 bits; conditional E-value: 5.9e-12 WDR55 19 ediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllv.idenllatG 113 + +++g+ +G+v ++ s + ++ +++ sl+ h++++ +v+ + +k++s s D+si+ d+e++k+++ ++ + ++++ ++ l+++ FUN_001198-T1 73 R-RLVLGSDSGSVDIWCLSGSFQNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSrAEQDLFVSV 167 4.46789999*********99999*************************************************977776666655426788***** PP WDR55 114 dddGtvklWDlRkkkavmelkeh 136 dG++ lWD R k ++l++ FUN_001198-T1 168 SQDGCIILWDARAPKIATKLTDS 190 *************9999888765 PP == domain 2 score: 18.0 bits; conditional E-value: 2.3e-06 WDR55 19 ediiavgtidGdvllykysneenenkellslehhkkscraveFsed.GkklfsvskDksiavldvetgklkkkiekahespiysl..lvidenlla 111 ++++avg dG+v l++ +n + + +l+ hh++++ +++Fs + l +vs D ++v d+ + +++ + + h++ + l + +d++l+ FUN_001198-T1 207 HHLLAVGYEDGSVCLCNIQNPK---QPVLTYCHHERAVNKLAFSPRsPEWLATVSDDMWVHVQDCLNDTTVLRS-DEHSEVVRGLawSPVDDTLYT 298 5799**************9865...568999*************751577999999999*****9877666554.467766654411456666665 PP WDR55 112 tG 113 +G FUN_001198-T1 299 SG 300 55 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 4.1 7.2e-05 0.053 110 192 .. 33 123 .. 7 123 .. 0.72 2 ! 32.0 0.7 1.3e-10 9.7e-08 150 217 .. 121 191 .. 116 204 .. 0.82 3 ! 17.3 0.0 3.8e-06 0.0028 7 66 .. 205 266 .. 198 307 .. 0.80 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 7.2e-05 Beta-prop_TEP1_2nd 110 rdrsllcWdvrvp.kaPvlirsllachrd.WvtgcaWtkddllvscssdGsvglWdi....ekeqrlgkflGhqsavsavv..aveehvvs 192 r + +W ++ kaP + ++ + c + t W+++ lv +s+ Gsv +W + ++ +++ ++ h+++vs+v +++ ++vs FUN_001198-T1 33 RTWNGSLWLFKDRaKAPDVQYCSAGCSTEsGTTDIKWIDSRRLVLGSDSGSVDIWCLsgsfQNLENMASLTDHDNTVSSVSvdCIKSKIVS 123 44444445544433899888888888766157789********************76111145567788899******8643388888886 PP == domain 2 score: 32.0 bits; conditional E-value: 1.3e-10 Beta-prop_TEP1_2nd 150 lvscssdGsvglWdiekeqrlgkflGhqsav.savv..aveehvvsvgrdGllkvWdlqGveltsikahsg 217 +vs+s d s+ Wdie+e+ + + Gh v sa+ a+++ vsv++dG ++ Wd + +++ ++s+ FUN_001198-T1 121 IVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVwSAIYsrAEQDLFVSVSQDGCIILWDARAPKIATKLTDSS 191 79**************************9994555433677889**************9999888777775 PP == domain 3 score: 17.3 bits; conditional E-value: 3.8e-06 Beta-prop_TEP1_2nd 7 lsdkvlvsGaedgslqvWkleesssqcllllkahqkavlglals...qkllasasedltvrlW 66 l++++l G edgs++ ++++ +q +l+++ h++av la s + la++s+d+ v++ FUN_001198-T1 205 LDHHLLAVGYEDGSVCLCNIQN-PKQPVLTYCHHERAVNKLAFSprsPEWLATVSDDMWVHVQ 266 88999************99976.56788899***********86222689*******988753 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.8 0.4 0.00023 0.17 118 266 .. 16 157 .. 9 157 .. 0.79 2 ! 19.2 1.3 1.3e-06 0.00094 130 271 .. 73 208 .. 64 209 .. 0.64 3 ! 14.5 0.0 3.5e-05 0.025 209 258 .. 188 238 .. 181 240 .. 0.83 4 ! 18.5 0.0 2e-06 0.0015 130 230 .. 208 297 .. 206 306 .. 0.79 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00023 Beta-prop_RIG_2nd 118 kiervslvsvrdslLlvgtedGalqllerkkelekayskllkqeallsryitdiawsplesnklAvvandkvivilefkeeernletlkkit 209 +ie+ ++++v s L t +G+l l++ + ++ ++ + ++ +++ tdi w +s l + + + i ++ + +nle ++t FUN_001198-T1 16 DIEEDGTLAVASSALTGRTWNGSLWLFKDRAKAPD-VQ-YCSAGCSTESGTTDIKWI--DSRRLVLGSDSGSVDIWCLSGSFQNLENMASLT 103 57777889999999999999999999988777663.33.345555566778999998..666899999999999999998888888877776 PP Beta-prop_RIG_2nd 210 asaekasitsvkwsnansnlllsfsidgkvkvWdleepekeeltitykcpmlcglFl 266 ++ + ++sv+ + ++s s d ++k Wd+e+++ + ++ ++ +++++++ FUN_001198-T1 104 DHD--NTVSSVSVDCI-KSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYS 157 555..56666665555.5567899******************9999**9*****985 PP == domain 2 score: 19.2 bits; conditional E-value: 1.3e-06 Beta-prop_RIG_2nd 130 slLlvgtedGalqllerkkelekayskllkqeallsryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvk 221 + L++g+++G++ + + +++ + ++ ++ + ++++++ +++ ++s+ + v+ + i e + e +++ ++ +++ + s+ FUN_001198-T1 73 RRLVLGSDSGSVDIWCLSGSFQ-NLEN-MASLTDHDNTVSSVSVDCIKSK-I--VSGSWDRSIKEWDIE----QEKCVRSYKGHSDMVWSAI 155 6677777777777776666655.3332.3333445566666666655533.2..233333334444433....23344567889******** PP Beta-prop_RIG_2nd 222 wsnansnlllsfsidgkvkvWdleepek.eeltit.ykcpm.lcglFlPtden 271 +s+a+++l++s+s dg++ +Wd ++p+ ++lt + y++++ c ++P d + FUN_001198-T1 156 YSRAEQDLFVSVSQDGCIILWDARAPKIaTKLTDSsYYASIpHCVDWSPLDHH 208 ***************************84456644455555267779999875 PP == domain 3 score: 14.5 bits; conditional E-value: 3.5e-05 Beta-prop_RIG_2nd 209 tasaekasi.tsvkwsnansnlllsfsidgkvkvWdleepekeeltitykc 258 t s+ asi ++v ws+ +++ll dg+v++ ++++p+++ lt+ +++ FUN_001198-T1 188 TDSSYYASIpHCVDWSPLDHHLLAVGYEDGSVCLCNIQNPKQPVLTYCHHE 238 555555666479*********9999999***************99998875 PP == domain 4 score: 18.5 bits; conditional E-value: 2e-06 Beta-prop_RIG_2nd 130 slLlvgtedGalqllerkkelekayskllkqeallsryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvk 221 +lL+vg edG++ l++ ++ + + + ++r +++ a+sp + ++lA v+ d +++ + ++++ l ++++ + ++ FUN_001198-T1 208 HLLAVGYEDGSVCLCNIQNPKQPVLT-----YCHHERAVNKLAFSPRSPEWLATVSDDMWVHVQDCLNDTTVL------RSDEHSEVVRGLA 288 689**************988775444.....3457899*************************9887655544......4556777777777 PP Beta-prop_RIG_2nd 222 wsnansnll 230 ws+ ++ l FUN_001198-T1 289 WSPVDDTLY 297 777776665 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.3 0.0026 1.9 205 263 .. 72 133 .. 58 136 .. 0.79 2 ! 12.1 0.3 0.00018 0.13 124 226 .. 76 182 .. 74 194 .. 0.64 3 ! 31.7 0.0 1.9e-10 1.4e-07 126 266 .] 167 311 .. 161 311 .. 0.84 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0026 Beta-prop_WDR36-Utp21_1st 205 epvlatgsssGdialwdLekr.rlvhvlrna..HeggvtkleflpgqpllvtsgaDNslkew 263 + l+ gs+sG++ +w L+ + + ++ + + H+++v+++++ + +v+ + D s+kew FUN_001198-T1 72 SRRLVLGSDSGSVDIWCLSGSfQNLENMASLtdHDNTVSSVSVDCIKSKIVSGSWDRSIKEW 133 56699**************9884444444332388999999988888999************ PP == domain 2 score: 12.1 bits; conditional E-value: 0.00018 Beta-prop_WDR36-Utp21_1st 124 lvgskqGslqlwNirtg.kliytf...ksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtD 203 ++gs++Gs+++w ++ + + + ++ + ++++++++ ++ + + g + +i +i++++ + ++k +++ v s + FUN_001198-T1 76 VLGSDSGSVDIWCLSGSfQNLENMaslTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRA 159 677777777777665431222222111344477777777777777777777777777777777777777777777777777777 PP Beta-prop_WDR36-Utp21_1st 204 gepvlatgsssGdialwdLekrr 226 ++ ++++ s++G i+lwd + FUN_001198-T1 160 EQDLFVSVSQDGCIILWDARAPK 182 77777777777777777765555 PP == domain 3 score: 31.7 bits; conditional E-value: 1.9e-10 Beta-prop_WDR36-Utp21_1st 126 gskqGslqlwNirtgkliytfksfk..sai.taleqsp.aldvvaiglasGeivlhnikk.detllklkqeegpvtsisFrtDg 204 +s++G + lw+ r k+ +++ ++ ++i ++ sp +++a+g+++G+++l ni+ + +l++ ++e +v++++F + FUN_001198-T1 167 VSQDGCIILWDARAPKIATKLTDSSyyASIpHCVDWSPlDHHLLAVGYEDGSVCLCNIQNpKQPVLTYCHHERAVNKLAFSPRS 250 689******************8666666663788889966789***************98356799999999************ PP Beta-prop_WDR36-Utp21_1st 205 epvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkewifD 266 ++ lat s++ + + d + + v ++ H++ v +l + p l tsg ++ fD FUN_001198-T1 251 PEWLATVSDDMWVHVQDCLNDTTVLR-SDEHSEVVRGLAWSPVDDTLYTSGWGQQIFSHAFD 311 *****************665554433.36899*****************9976666666655 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.2 0.3 4.3e-13 3.2e-10 40 244 .. 94 296 .. 60 309 .. 0.81 Alignments for each domain: == domain 1 score: 40.2 bits; conditional E-value: 4.3e-13 EIF3I 40 enGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletkt.avrsvefsesgkllllvtdkvmgkkseivvldirdeeeee 134 +n e + +++ h +v s+ vd +++v+gs d ++k Wd+e+ k++++++ ++ v s +s ++ l++++ ++++ i + d r + FUN_001198-T1 94 QNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSdMVWSAIYSRAEQDLFVSV----SQDGCIILWDARAPKI-- 183 5789999********************************************98772567778888888887765....5678899999988764.. PP EIF3I 135 eeepvlkieveeskvtvalwsaldktii.tghedgeiskydlktgek.lksvkehekqitdlqlskdk.tylitaskDktaklldv.etlevlkty 226 +++++ + s +++ ws ld++++ +g edg+++ ++++ ++ + + +he++++ l +s+ + ++l t s D ++ d+ ++ +vl++ FUN_001198-T1 184 -ATKLTDSSYYASIPHCVDWSPLDHHLLaVGYEDGSVCLCNIQNPKQpVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHVQDClNDTTVLRSD 278 .445666666677778999****9876527************9976637788899**********8653789999999999999973567777777 PP EIF3I 227 kterpvnsaaisplkdfv 244 + v a sp+ d + FUN_001198-T1 279 EHSEVVRGLAWSPVDDTL 296 777777777777777765 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 2.6 3.9e-09 2.8e-06 249 339 .. 84 176 .. 48 178 .. 0.82 2 ! 12.5 0.0 9.8e-05 0.071 99 187 .. 206 292 .. 196 351 .. 0.80 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 3.9e-09 WD40_MABP1-WDR62_2nd 249 irvynvssgkqk.ksfkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhl.isvsgDsC 335 + ++ +s + q+ +++ + + +d t+ v++D + +++ + d++++ +d e+ +cv + Ghs++v + +++ + l +svs D+C FUN_001198-T1 84 VDIWCLSGSFQNlENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRAEQDLfVSVSQDGC 172 5555555554441344444556889999****************************************99999987776549******* PP WD40_MABP1-WDR62_2nd 336 ifvW 339 i +W FUN_001198-T1 173 IILW 176 **** PP == domain 2 score: 12.5 bits; conditional E-value: 9.8e-05 WD40_MABP1-WDR62_2nd 99 dgkhlasGDrsGniriydletlee.llkieahdsevlcleyskpetglkllasasRDRlihvfdvekdysllqtlddhsssitavkfae 186 d + la G G++ + ++++ ++ +l+ h+ v l +s + + la+ s D +hv d +d ++l++ d+hs + + ++ FUN_001198-T1 206 DHHLLAVGYEDGSVCLCNIQNPKQpVLTYCHHERAVNKLAFSPRS--PEWLATVSDDMWVHVQDCLNDTTVLRS-DEHSEVVRGLAWSP 291 66779**************9987636777788999999***9975..679******************999886.99999887776655 PP WD40_MABP1-WDR62_2nd 187 e 187 FUN_001198-T1 292 V 292 5 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 5.4e-06 0.0039 7 111 .. 73 182 .. 70 185 .. 0.80 2 ! 26.6 0.0 6.2e-09 4.5e-06 9 98 .. 164 258 .. 159 276 .. 0.78 3 ? 3.1 0.0 0.086 63 60 98 .. 263 301 .. 251 328 .. 0.73 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 5.4e-06 Beta-prop_WDR90_POC16_2nd 7 rqlatvseDetiriWdld.tlqqlydfsa...seeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvf 86 r+l+ s+ ++ iW l+ ++q l ++ + ++++ ++v+ +k+ +++G+ + ++ +++e+ + + +k h v + ++ FUN_001198-T1 73 RRLVLGSDSGSVDIWCLSgSFQNLENMASltdHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIY 156 67777788899999988634555555554111567788899999**************************************** PP Beta-prop_WDR90_POC16_2nd 87 spdgeylysa.cslGslalydaseee 111 s+ + l+ + ++ G + l+da +++ FUN_001198-T1 157 SRAEQDLFVSvSQDGCIILWDARAPK 182 *9998888551567999999998776 PP == domain 2 score: 26.6 bits; conditional E-value: 6.2e-09 Beta-prop_WDR90_POC16_2nd 9 latvseDetiriWdldt...lqqlydfsaseeaPcavafhPsk.qvfacGfssGvvrvfsveatsl.laehkqhrgkvtglvfs 87 ++ vs+D i +Wd + ++l d s + +P +v + P + +++a G+++G v +++++ + + + +h+ +v l+fs FUN_001198-T1 164 FVSVSQDGCIILWDARApkiATKLTDSSYYASIPHCVDWSPLDhHLLAVGYEDGSVCLCNIQNPKQpVLTYCHHERAVNKLAFS 247 568***********9873335789999999***********86257899*************987526788889999******* PP Beta-prop_WDR90_POC16_2nd 88 pdgeylysacs 98 p + ++ s FUN_001198-T1 248 PRSPEWLATVS 258 *8765554444 PP == domain 3 score: 3.1 bits; conditional E-value: 0.086 Beta-prop_WDR90_POC16_2nd 60 vrvfsveatsllaehkqhrgkvtglvfspdgeylysacs 98 v+v + + + + +h v gl+ sp ++ ly+++ FUN_001198-T1 263 VHVQDCLNDTTVLRSDEHSEVVRGLAWSPVDDTLYTSGW 301 555555555666677889999999999999999999875 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.6 4.7e-11 3.4e-08 137 187 .. 102 151 .. 74 160 .. 0.81 2 ? 2.8 0.0 0.081 59 263 307 .. 160 203 .. 153 235 .. 0.64 3 ? 3.6 0.1 0.047 34 139 199 .. 278 339 .. 264 370 .. 0.75 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 4.7e-11 Beta-prop_SPT8 137 lkakhsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgatsel 187 l +h n+v+ + ++ + k++sgswd+ i ewd++ +k +++ykg++ + FUN_001198-T1 102 LT-DHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMV 151 33.7******************************************98765 PP == domain 2 score: 2.8 bits; conditional E-value: 0.081 Beta-prop_SPT8 263 desvfltsGlnGsiniwdkrnskapvlklerga..ktppwclsacws 307 ++ f+ +G+i +wd r k kl+ ++ p c++ ws FUN_001198-T1 160 EQDLFVSVSQDGCIILWDARAPKIAT-KLTDSSyyASIPHCVD--WS 203 56789999999999999999876544.6665541134456654..55 PP == domain 3 score: 3.6 bits; conditional E-value: 0.047 Beta-prop_SPT8 139 akhsnvvnilrlnstedkflsgswdkkilewdln.tgkvineykgatselsalelrplfstv 199 +hs+vv l + +d + +++w ++i+ ++ g+ + ++++s+ +++ + + v FUN_001198-T1 278 DEHSEVVRGLAWSPVDDTLYTSGWGQQIFSHAFDcSGQSDLNVEASKSQATSVCMEIFNGEV 339 37***************************999986677777788888888888776555533 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 3.3 2.4e+03 178 195 .. 12 29 .. 9 32 .. 0.87 2 ! 32.4 3.7 1.1e-10 7.8e-08 185 287 .. 70 177 .. 63 183 .. 0.86 3 ! 6.8 0.0 0.0068 4.9 41 106 .. 197 265 .. 182 282 .. 0.80 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 3.3 Beta-prop_WDR3_2nd 178 vlsldissDsklivtgsa 195 v ++di +D++l v++sa FUN_001198-T1 12 VDAIDIEEDGTLAVASSA 29 66899*******999997 PP == domain 2 score: 32.4 bits; conditional E-value: 1.1e-10 Beta-prop_WDR3_2nd 185 sDsklivtgsaDknikiwGld..fGDch..kslfahddsvmsvafvpktHylfsagkdkkvkyWDadkfekiqtleghagevwalavss.k 270 Ds+ +v gs ++ iw l f ++ sl+ hd++v sv++ ++ s + d+++k+WD ++ +++ + +gh++ vw+ s+ + FUN_001198-T1 70 IDSRRLVLGSDSGSVDIWCLSgsFQNLEnmASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRaE 160 588899999999999999985337665422699**************9***********************************98888724 PP Beta-prop_WDR3_2nd 271 gkfvvsashDksiRlwe 287 +++vs+s+D i lw+ FUN_001198-T1 161 QDLFVSVSQDGCIILWD 177 6799*********9997 PP == domain 3 score: 6.8 bits; conditional E-value: 0.0068 Beta-prop_WDR3_2nd 41 alclafvpgdrhvl.vgtkdGklevldlasael.letieahegavwsvaltpde.kglvtggaDkkvkf 106 c+ + p d+h+l vg +dG++ ++++++ ++ + t he av ++a +p + + l t + D v++ FUN_001198-T1 197 PHCVDWSPLDHHLLaVGYEDGSVCLCNIQNPKQpVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHV 265 5789999999987648************99765378888999********9976255667777777765 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.9 5.3 1e-09 7.5e-07 149 293 .. 67 218 .. 29 225 .. 0.80 2 ! 9.2 0.0 0.001 0.76 195 273 .. 206 287 .. 199 300 .. 0.81 3 ? -1.9 0.1 2.5 1.8e+03 157 205 .. 320 371 .. 310 374 .. 0.64 Alignments for each domain: == domain 1 score: 28.9 bits; conditional E-value: 1e-09 WD40_Gbeta 149 crflddnqivtssgdttcalwdietgqqt....tvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdi.naiaffpnge 239 +++d ++v s ++ +w + q+ ++++ h v s+s+ +vsg+ d s+k wd+ + c +++ gh + ai + + FUN_001198-T1 67 IKWIDSRRLVLGSDSGSVDIWCLSGSFQNlenmASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVwSAIYSRAEQD 162 57889999999888888888888776664222267899*******************************************776624555566778 PP WD40_Gbeta 240 alatgsddatcrlfdlradqellvyshdniicgit.svafsk.sgrlllagyddfn 293 +++ s+d + l+d ra + + + + i v +s +ll gy+d FUN_001198-T1 163 LFVSVSQDGCIILWDARAPKIATKLTDSSYYASIPhCVDWSPlDHHLLAVGYEDGS 218 8999**************99999999888888885267888514556667998854 PP == domain 2 score: 9.2 bits; conditional E-value: 0.001 WD40_Gbeta 195 dtrlfvsgacdasaklwdvregl.crqtfighesdinaiaffpng.ealatgsddatcrlfdlradqellvy.shdniicgi 273 d +l+ g d s+ l ++++ t+ he +n +af p e lat sdd +++ d d +l h +++ g+ FUN_001198-T1 206 DHHLLAVGYEDGSVCLCNIQNPKqPVLTYCHHERAVNKLAFSPRSpEWLATVSDDMWVHVQDCLNDTTVLRSdEHSEVVRGL 287 6677888889999999999986515679***************863789*************99998877541566777665 PP == domain 3 score: -1.9 bits; conditional E-value: 2.5 WD40_Gbeta 157 ivtssgdttcalwdietgq...qttvfvghtgdvmslslapdtrlfvsgacd 205 + +s ++t +i g+ +t+ + d+m l + d +++vs +d FUN_001198-T1 320 VEASKSQATSVCMEIFNGEvngSETCQDEENADAMELDGTQDIKTVVSCNVD 371 5555555555555554443111556666778999999999999999998877 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 2.5 1.1e-05 0.0079 135 208 .. 66 142 .. 61 145 .. 0.84 2 ! 15.9 0.1 9.6e-06 0.007 124 202 .. 142 225 .. 140 230 .. 0.79 3 ! 7.5 0.0 0.0034 2.5 67 97 .. 235 266 .. 228 282 .. 0.78 4 ? 1.2 0.0 0.27 2e+02 169 190 .. 278 299 .. 265 307 .. 0.80 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.1e-05 Beta-prop_CAF1B_HIR1 135 Dlswspdskkli....sgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkvva 208 D+ w ds++l+ sgsvD + +++ +++a l+dh + v +v+ d ++ +++ s Drs++ +di+++k+v FUN_001198-T1 66 DIKWI-DSRRLVlgsdSGSVDIWCLSGSFQNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVR 142 67774.55555524446778877777789999*******************************************986 PP == domain 2 score: 15.9 bits; conditional E-value: 9.6e-06 Beta-prop_CAF1B_HIR1 124 kvlrGhledvyDlswspdskkl.isgsvDntailWdvekgkklailkdhkgfv...qgvawdPknqyvatl.ssDrslrifdik 202 + +Gh + v+ +s+ ++ l +s s D +ilWd + k + l+d+ + v w P+++ + ++ D s+ + +i+ FUN_001198-T1 142 RSYKGHSDMVWSAIYSRAEQDLfVSVSQDGCIILWDARAPKIATKLTDSSYYAsipHCVDWSPLDHHLLAVgYEDGSVCLCNIQ 225 6689************998876489**********************99887622369*****998765541456666666665 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0034 Beta-prop_CAF1B_HIR1 67 trhqkavnvvrfspsg.elLasgdDesviiiW 97 +h++avn fsp+ e La+ +D+ + + FUN_001198-T1 235 CHHERAVNKLAFSPRSpEWLATVSDDMWVHVQ 266 68***********97538********887664 PP == domain 4 score: 1.2 bits; conditional E-value: 0.27 Beta-prop_CAF1B_HIR1 169 kdhkgfvqgvawdPknqyvatl 190 ++h + v+g aw P ++ + t FUN_001198-T1 278 DEHSEVVRGLAWSPVDDTLYTS 299 5899999999999999988775 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.1 0.013 9.4 213 280 .] 68 133 .. 43 133 .. 0.83 2 ! 19.2 0.4 1.3e-06 0.00095 139 236 .. 86 180 .. 75 195 .. 0.79 3 ! 15.3 0.1 2e-05 0.015 162 241 .. 198 275 .. 184 305 .. 0.78 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.013 Beta-prop_EIPR1 213 dpakknklltagddgvvlihDiRydgs.stveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 + +l+ d g v i+ + gs + +e++ l h+ tv++v++ + + i+s+s d+ +k w FUN_001198-T1 68 KWIDSRRLVLGSDSGSVDIWCLS--GSfQNLENMASLTDHDNTVSSVSVDCIKSK-IVSGSWDRSIKEW 133 455667788888999*****999..88899*******************998876.7899999999877 PP == domain 2 score: 19.2 bits; conditional E-value: 1.3e-06 Beta-prop_EIPR1 139 lvsldeskkgke.vskyslggeelrvaAldphdsslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvli 231 ++ l+ s + e +++ + ++++++ d s++v + + +++ +D+ + k ++ ++ + ++v + +++a++ +++ +dg++ + FUN_001198-T1 86 IWCLSGSFQNLEnMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVR----SYKGHSDMVWSAIYSRAEQDLFVSVSQDGCIIL 175 6667777666663444444559999999**********************9999888....3444478888889******************** PP Beta-prop_EIPR1 232 hDiRy 236 +D R FUN_001198-T1 176 WDARA 180 ***93 PP == domain 3 score: 15.3 bits; conditional E-value: 2e-05 Beta-prop_EIPR1 162 rvaAldphdsslvlvace.sglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsst 241 ++ + p d +l +v e ++ l + + k+ +++h+ v+++ f+p ++ l+t dd v++ D d++++ FUN_001198-T1 198 HCVDWSPLDHHLLAVGYEdGSVCLCNIQNPKQPV---LTYCHHERAVNKLAFSPRSPEWLATVSDDMWVHVQDCLNDTTVL 275 6788999999999999998889999987766655...899999******************************88555433 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 1.0 2.5e-07 0.00018 60 136 .. 104 180 .. 92 198 .. 0.84 2 ? 0.9 0.0 0.43 3.2e+02 110 141 .. 199 231 .. 182 236 .. 0.85 3 ! 10.4 0.1 0.00057 0.41 61 119 .. 237 296 .. 233 312 .. 0.81 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 2.5e-07 WD40_RFWD3 60 lHskaiRdlaFnseqdslllsaslDktlkltsllsntvvqtYetdsp.vWsCcWseddsnylyaGlqnGsvlvfDiRq 136 H +++ +++ ++ +s ++s s D+++k ++++++ v++Y+ +s+ vWs +s ++ ++ + q+G ++++D R FUN_001198-T1 104 DHDNTVSSVSVDCI-KSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDmVWSAIYSRAEQDLFVSVSQDGCIILWDARA 180 57778888888877.556789**********************876539***************************96 PP == domain 2 score: 0.9 bits; conditional E-value: 0.43 WD40_RFWD3 110 Cc.WseddsnylyaGlqnGsvlvfDiRqtssev 141 C+ Ws d+ +l +G ++Gsv++ i + +++v FUN_001198-T1 199 CVdWSPLDHHLLAVGYEDGSVCLCNIQNPKQPV 231 434*******************99998877766 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00057 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsntvvqtYetd.spvWsCcWseddsny 119 H++a+ laF++++ ++l ++s D +++ + l++t+v + + + v +Ws d ++ FUN_001198-T1 237 HERAVNKLAFSPRSPEWLATVSDDMWVHVQDCLNDTTVLRSDEHsEVVRGLAWSPVDDTL 296 9999******************************99886655440455677888777665 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.027 20 21 65 .. 92 135 .. 69 137 .. 0.71 2 ! 18.1 0.1 2.5e-06 0.0018 15 65 .. 128 178 .. 119 195 .. 0.81 3 ! 9.1 0.0 0.0014 1 188 245 .. 199 255 .. 182 273 .. 0.76 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.027 Beta-prop_WDR75_1st 21 ststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 s + e + +l h + v+ v ++ + ++ s s d +++ wd FUN_001198-T1 92 SFQNLENMASLTDHDNTVSSVSVDCI-KSKIVSGSWDRSIKEWDI 135 3345688999************9986.56899***********96 PP == domain 2 score: 18.1 bits; conditional E-value: 2.5e-06 Beta-prop_WDR75_1st 15 dsvkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 s+k + + e+cv++ kgh+d+v + +++ s s dg + lwd FUN_001198-T1 128 RSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRAEQDLFVSVSQDGCIILWDA 178 478999999***************77666666666677************5 PP == domain 3 score: 9.1 bits; conditional E-value: 0.0014 Beta-prop_WDR75_1st 188 cvachpkdd.ciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnlls 245 cv p d +a G+edG + l n k+ t h+ av++l+f+p + l+ FUN_001198-T1 199 CVDWSPLDHhLLAVGYEDGSVCLCNIQNPKQ-PVL-TYCHHERAVNKLAFSPRSPEWLA 255 7777776642689*********986555554.444.3445999*********9877665 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.2 1.3e-09 9.5e-07 220 309 .. 97 185 .. 64 205 .. 0.82 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.3e-09 Beta-prop_DCAF4 220 gwkatrlfhdsavtsvqllqeeqlllaadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllr 309 a+ hd +v+sv + + +++ ik wd+ ++kcv+ y+Gh + ++ + e+ l v+v qd +w + ++ + FUN_001198-T1 97 ENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSD-MVWSAIYSRAEQDLFVSVSQDGCIILWDARAPKIAT 185 455666789*********99999****************************85.67889999*************9999**987766654 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 1.3 0.00052 0.38 170 257 .. 75 165 .. 57 174 .. 0.48 2 ! 11.7 0.6 0.00026 0.19 22 232 .. 119 183 .. 103 217 .. 0.42 3 ! 12.6 0.1 0.00014 0.1 56 162 .. 231 332 .. 223 341 .. 0.77 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00052 Beta-prop_EML 170 vitGdsnGnilvWskgtn..kisk.avkkahegsvfsllvlkdgtllsgggkdgkivawdanleklketelpesaggvraivegkgdqllv 257 ++ G +G++ +W +++ ++++ a + h+++v+s+ v ++ +++g d++i++wd + ek+ + +s ai + ++ l+v FUN_001198-T1 75 LVLGSDSGSVDIWCLSGSfqNLENmASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRAEQDLFV 165 5556666666666544322122220222456666666665554444444566666666665555543322222222333333333333333 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00026 Beta-prop_EML 22 llvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavef 117 +++G + i+ Wd+e+ ++++ + k ++ v + +s+a FUN_001198-T1 119 SKIVSGSWDR----------SIKEWDIEQEKCVRSY-K-GHSDMVWSAIYSRA------------------------------------------- 159 4444443321..........2333444444444433.1.13334444444433........................................... PP Beta-prop_EML 118 hpldknllvtcGkkhiaFWtlegkklekkkgifeksekpkyvlclafsengdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtll 213 ++ l FUN_001198-T1 160 -------------------------------------------------------------------------------------------EQDLF 164 ...........................................................................................33333 PP Beta-prop_EML 214 sgggkdgkivawdanlekl 232 ++ +dg+i+ wda+ k+ FUN_001198-T1 165 VSVSQDGCIILWDARAPKI 183 3333333333333333332 PP == domain 3 score: 12.6 bits; conditional E-value: 0.00014 Beta-prop_EML 56 vlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhiaFWtlegkklekkkgife 151 vl+ ++er+v laFs ++ + La+v ++ + v d +++ + ++ +++ v +++++p d+ +l t G + F + + + +++ ++e FUN_001198-T1 231 VLTYCHHERAVNKLAFSPRS-PEWLATVSDDM--WVHVQDCLNDTTVLRSDEHSEVVRGLAWSPVDD-TLYTSGWGQQIFSHAFDCSGQSD-LNVE 321 5666789**********866.79****97765..89999*************************986.57799988877766554443333.3344 PP Beta-prop_EML 152 ksekpkyvlcl 162 s+++ + +c+ FUN_001198-T1 322 ASKSQATSVCM 332 44455555555 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.4 0.4 2.9e+02 34 82 .. 102 150 .. 67 157 .. 0.75 2 ? 2.3 0.0 0.38 2.8e+02 50 89 .. 161 203 .. 147 205 .. 0.78 3 ! 14.9 0.0 4.7e-05 0.034 42 87 .. 198 245 .. 159 249 .. 0.64 4 ? 5.1 0.0 0.052 38 10 53 .. 254 296 .. 244 305 .. 0.76 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.4 ANAPC4_WD40 34 eekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdk 82 ++d++v+s++ ++ + d +++ d+e+ k+v+s++ +sd FUN_001198-T1 102 LTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDM 150 4677888888888888888999999999**************9999883 PP == domain 2 score: 2.3 bits; conditional E-value: 0.38 ANAPC4_WD40 50 GklLavaysdgevrlldvesgklvhslsaksdk...itcleWa 89 l++ + +dg + l d+ k++ +l+ +s + c++W+ FUN_001198-T1 161 QDLFVSVSQDGCIILWDARAPKIATKLTDSSYYasiPHCVDWS 203 45667777899************99997776656778888886 PP == domain 3 score: 14.9 bits; conditional E-value: 4.7e-05 ANAPC4_WD40 42 tslaWkp.dGklLavaysdgevrlldvesgk.lvhslsaksdkitcle 87 +++ W+p d +lLav+y+dg+v l+++++ k v ++ ++ ++++l FUN_001198-T1 198 HCVDWSPlDHHLLAVGYEDGSVCLCNIQNPKqPVLTYCHHERAVNKLA 245 478999856789***************996613434333333366655 PP == domain 4 score: 5.1 bits; conditional E-value: 0.052 ANAPC4_WD40 10 iAlatedgevllkR.lnwqrvwklseekedsevtslaWkpdGklL 53 +A +++d+ v+++ ln v +++++ v++laW+p L FUN_001198-T1 254 LATVSDDMWVHVQDcLNDTTVLRS--DEHSEVVRGLAWSPVDDTL 296 677777777777642577788777..9999*********987766 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.7 0.015 11 26 135 .. 20 139 .. 6 154 .. 0.73 2 ! 17.0 0.0 3.6e-06 0.0026 37 113 .. 168 249 .. 150 264 .. 0.78 3 ? -1.2 0.0 1.2 8.6e+02 98 156 .. 277 335 .. 250 351 .. 0.69 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.015 Beta-prop_IFT140_1st 26 splLAvasv...seesgGsvdlyleegek..vedak..iersvqvtvlsWHPtkkilavgwesGevlvlne....qdkeltelpklhka 103 LAvas+ ++ Gs+ l++++ v+ ++ + ++ +t ++W +++ l++g +sG v ++ q+ e ++ + h+ FUN_001198-T1 20 DGTLAVASSaltGRTWNGSLWLFKDRAKApdVQYCSagCSTESGTTDIKWIDSRR-LVLGSDSGSVDIWCLsgsfQNLENMASLTDHDN 107 567888886222356689999999877641144444114556667899**99887.789*******99975121144555666678999 PP Beta-prop_IFT140_1st 104 eitvlewssngsrLvsgdksGvlvvWkldqrG 135 +++ ++ s++vsg ++ W ++q FUN_001198-T1 108 TVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEK 139 99999999999******999999999988765 PP == domain 2 score: 17.0 bits; conditional E-value: 3.6e-06 Beta-prop_IFT140_1st 37 esgGsvdlyleegekvedakiersvq...vtvlsWHPt.kkilavgwesGevlvlneqdkeltelpk.lhkaeitvlewssn 113 ++ G++ l+ + k++++ ++ s+ + ++ W P +++lavg+e+G v++ n q+ ++ l+ +h+ +++ l++s FUN_001198-T1 168 SQDGCIILWDARAPKIATKLTDSSYYasiPHCVDWSPLdHHLLAVGYEDGSVCLCNIQNPKQPVLTYcHHERAVNKLAFSPR 249 566777777777777777666665541116799****735689***************999988776377889999999976 PP == domain 3 score: -1.2 bits; conditional E-value: 1.2 Beta-prop_IFT140_1st 98 pklhkaeitvlewssngsrLvsgdksGvlvvWkldqrGrlqqspllkhelkkpltqcif 156 ++ h+ + l+ws +L ++ ++ d G+ + + ++ ++++ if FUN_001198-T1 277 SDEHSEVVRGLAWSPVDDTLYTSGWGQQIFSHAFDCSGQSDLNVEASKSQATSVCMEIF 335 45688888889999988888888777777777777777766665555555555555555 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.8 2.6e-05 0.019 1 38 [. 105 144 .. 105 153 .. 0.79 2 ? 6.2 0.0 0.02 15 11 33 .. 160 182 .. 147 191 .. 0.84 3 ? -2.2 0.0 8.6 6.3e+03 20 49 .. 215 246 .. 199 265 .. 0.60 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 2.6e-05 Beta-prop_TEP1_C 1 hsdrisal..kltddliisAseDrtvKlWdretkkqvGlF 38 h +++s++ + +++ i+s s Dr++K Wd e++k v + FUN_001198-T1 105 HDNTVSSVsvDCIKSKIVSGSWDRSIKEWDIEQEKCVRSY 144 55666655115689********************998766 PP == domain 2 score: 6.2 bits; conditional E-value: 0.02 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdretkk 33 +dl +s s+D ++ lWd + k FUN_001198-T1 160 EQDLFVSVSQDGCIILWDARAPK 182 57899*************98766 PP == domain 3 score: -2.2 bits; conditional E-value: 8.6 Beta-prop_TEP1_C 20 eDrtvKlWdretkkqvGlFvCea..pvlvlev 49 eD +v l + ++ kq l +C+ +v l FUN_001198-T1 215 EDGSVCLCNIQNPKQPVLTYCHHerAVNKLAF 246 45566666666666666666653114444444 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 1.2 2.7e-05 0.02 79 155 .. 93 169 .. 70 175 .. 0.81 2 ! 9.5 0.0 0.0011 0.81 219 294 .. 153 228 .. 148 251 .. 0.71 3 ? 0.7 0.1 0.51 3.7e+02 65 202 .. 210 347 .. 205 362 .. 0.57 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.7e-05 Beta-prop_ACSF4 79 latgeilwkfktgdaiKsspvidsesglvvvgsydknlyaldvesgklvwklklggsifsspllskskesvlvatld 155 +++ e + + + d ss +d ++++v gs d+++ +d+e++k+v ++k ++ ++ s ++s++++ ++v + FUN_001198-T1 93 FQNLENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRAEQDLFVSVSQ 169 566666777777777778888999999************************************99999888887554 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0011 Beta-prop_ACSF4 219 sspvlvkseekivfgshdgllyclsvs.gellwkveldseifatPfvfeesegsnekllavastdGklflldletge 294 s ++ +++ +v s+dg+++ +++ ++ k++ +s + P +++ s +++llav +dG+++l++ ++ + FUN_001198-T1 153 SAIYSRAEQDLFVSVSQDGCIILWDARaPKIATKLTDSSYYASIPHCVDWSP-LDHHLLAVGYEDGSVCLCNIQNPK 228 4444444455567789********9964788888887777778899999765.56889*************988754 PP == domain 3 score: 0.7 bits; conditional E-value: 0.51 Beta-prop_ACSF4 65 vvvGcydgklycldlatge..ilwkfktgdaiKsspvidsesglvvvgsydknlyaldvesgklvwklklggsifsspllskskesvlvatldG 156 + vG dg+++ +++++ + +l ++ + a+ + ++ +++ s d +++ d+ ++++v +++ +++++ ++s +++++++ + FUN_001198-T1 210 LAVGYEDGSVCLCNIQNPKqpVLTYCHHERAVNKLAFSPRSPEWLATVSDDMWVHVQDCLNDTTVLRSDEHSEVVRGLAWSPVDDTLYTSGWGQ 303 5566666666666665533113334445555555555555566667777777777777777777777777777777777777777777777777 PP Beta-prop_ACSF4 157 tvaals.eesgeilWkvklesPiFsspvilsdevvvaevdgtvlcls 202 ++++ + sg+ +v++++ +++ + e++ +ev+g+ +c + FUN_001198-T1 304 QIFSHAfDCSGQSDLNVEASKS---QATSVCMEIFNGEVNGSETCQD 347 6666552224555555555543...3333333455566666555555 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.4 0.00021 0.15 117 158 .. 99 140 .. 83 145 .. 0.88 2 ! 17.6 2.5 2.6e-06 0.0019 94 163 .. 118 188 .. 97 226 .. 0.83 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00021 NBCH_WD40 117 vqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlrars 158 + s+ h + vs+v+v s +++Gs+d ++ w++ + + FUN_001198-T1 99 MASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKC 140 678899*******************************98765 PP == domain 2 score: 17.6 bits; conditional E-value: 2.6e-06 NBCH_WD40 94 nfliscGnwensfqvislsdGrlvqsirqhkdvv.scvavtsdgsvlatGsydttvmvwevlrarssekrv 163 + i G+w+ s + +++ + v+s + h d+v s++ ++ + ++ s+d +++w++ ++++k + FUN_001198-T1 118 KSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVwSAIYSRAEQDLFVSVSQDGCIILWDARAPKIATKLT 188 556889**************************886889999*******************98887777654 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.3 2.2e+02 110 132 .. 60 82 .. 37 85 .. 0.85 2 ? 4.4 0.0 0.028 21 51 105 .. 94 145 .. 86 155 .. 0.83 3 ? -0.9 0.0 1.2 8.6e+02 87 107 .. 170 190 .. 159 202 .. 0.89 4 ! 8.7 0.0 0.0015 1.1 77 130 .. 206 259 .. 169 264 .. 0.75 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.3 Beta-prop_VPS8 110 pgtavlhikFtddptlalvsDsg 132 ++++ ik++d+++l+l sDsg FUN_001198-T1 60 TESGTTDIKWIDSRRLVLGSDSG 82 5677889**************97 PP == domain 2 score: 4.4 bits; conditional E-value: 0.028 Beta-prop_VPS8 51 qtLklclgstakgaeqgaVsalafnadstrllaGyarGqilmwDlsngkllrtis 105 q+L+ + + + + Vs+++++ +++++ G + +i wD+++ k++r+ + FUN_001198-T1 94 QNLENMAS---LTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYK 145 55554333...3346789*********************************9875 PP == domain 3 score: -0.9 bits; conditional E-value: 1.2 Beta-prop_VPS8 87 rGqilmwDlsngkllrtisda 107 +G i++wD k+ ++++d FUN_001198-T1 170 DGCIILWDARAPKIATKLTDS 190 799************999996 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0015 Beta-prop_VPS8 77 dstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikFtddpt..lalvsD 130 d+ l++Gy++G++++ +++n k + + ++++av ++ F ++ la vsD FUN_001198-T1 206 DHHLLAVGYEDGSVCLCNIQNPK--QPVLTYCHHERAVNKLAFSPRSPewLATVSD 259 8999*****************99..4444455556688888887553223555555 PP >> Beta-prop_RIG_1st RIG first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.7 0.2 0.0089 6.5 407 449 .. 150 190 .. 93 202 .. 0.72 2 ! 10.8 0.1 0.00025 0.18 145 190 .. 199 245 .. 127 252 .. 0.69 3 ? -2.2 0.0 2.2 1.6e+03 55 76 .. 253 274 .. 247 285 .. 0.80 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0089 Beta-prop_RIG_1st 407 etlsktsvesarpdilLvSidaeevimiwnantgahcgknysk 449 + s + s ++ l vS++++ i++w+a+ ++++k + FUN_001198-T1 150 MVWS--AIYSRAEQDLFVSVSQDGCIILWDARAPKIATKLTDS 190 2333..44555567799**************999998886655 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00025 Beta-prop_RIG_1st 145 vlrcSPydenlfAvGTaaGlvlvcdlrkms.ivyklrghkseisgLa 190 ++ SP d +l+AvG + G+v +c++++ + v ++ h+ +++ La FUN_001198-T1 199 CVDWSPLDHHLLAVGYEDGSVCLCNIQNPKqPVLTYCHHERAVNKLA 245 45679*******************99864313444555566666665 PP == domain 3 score: -2.2 bits; conditional E-value: 2.2 Beta-prop_RIG_1st 55 afaivaeDlsvqvwDcalGeav 76 +a v +D+ v v Dc v FUN_001198-T1 253 WLATVSDDMWVHVQDCLNDTTV 274 5799999999999999766555 PP >> Beta-prop_NOL10_N Nucleolar protein 10-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 2.3e-05 0.016 132 215 .. 107 190 .. 91 236 .. 0.89 2 ? -0.5 0.0 1 7.4e+02 132 176 .. 282 330 .. 267 348 .. 0.75 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.3e-05 Beta-prop_NOL10_N 132 htmrslayhpytaellsggtsheifrlsletgafvesyktqsasginhvevfknhglimcagadgvveawdsragscasrltvt 215 t+ s++ ++++sg + i +e v syk +s + ++ l + dg + wd+ra a++lt + FUN_001198-T1 107 NTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKCVRSYKGHSDMVWSAIYSRAEQDLFVSVSQDGCIILWDARAPKIATKLTDS 190 57888899999999*****************************9999999999****************************965 PP == domain 2 score: -0.5 bits; conditional E-value: 1 Beta-prop_NOL10_N 132 htmrslayhpytaellsggtsheifrlsletg....afvesyktqsasg 176 +r la+ p l + g ++if +++ ve+ k+q++s FUN_001198-T1 282 EVVRGLAWSPVDDTLYTSGWGQQIFSHAFDCSgqsdLNVEASKSQATSV 330 5689999999999999999999999877664311114678888887764 PP >> MIOS_WD40 MIOS, WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.7 1.2e+03 184 254 .. 107 175 .. 93 202 .. 0.74 2 ! 13.8 0.0 3.9e-05 0.029 192 287 .. 203 299 .. 191 307 .. 0.78 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.7 MIOS_WD40 184 kavqgvtvdpyfhdrvasfyegqvaiwdlrkfekpvltlteqpkpltkvawcptrtgllatltrdsniirl 254 ++v v+vd v+ ++ + wd+ + ek v + + + + + l+ ++++d ii l FUN_001198-T1 107 NTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQ-EKCVRSYKGHSDMVWSAIYSRAEQDLFVSVSQDGCII-L 175 4677888888888888888888888888864.7888777777777777777777777777777777666.4 PP == domain 2 score: 13.8 bits; conditional E-value: 3.9e-05 MIOS_WD40 192 dpyfhdrvasfye.gqvaiwdlrkfekpvltlteqpkpltkvawcptrtgllatltrdsniirlydmqhtptpigdeteptiiersvqpcdnyias 286 p h +a ye g v++ ++++ ++pvlt + + + k+a+ p lat++ d + ++ t de + + p+d+ + + FUN_001198-T1 203 SPLDHHLLAVGYEdGSVCLCNIQNPKQPVLTYCHHERAVNKLAFSPRSPEWLATVSDDMWVHVQDCLNDTTVLRSDEHSEVVRGLAWSPVDDTLYT 298 5677777777665499**************************************998876655555566666667777777666677777776655 PP MIOS_WD40 287 f 287 FUN_001198-T1 299 S 299 5 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.2 0.015 11 138 181 .. 97 140 .. 71 193 .. 0.83 2 ? 6.2 0.0 0.0099 7.2 64 176 .. 200 310 .. 184 335 .. 0.81 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.015 Beta-prop_NUP159_NUP214 138 karslvsvlkenvssfdwsnkgkqlvvgladgtaqqlkpadgev 181 ++ + + + + vss+++++ ++++v g+ d++++ ++++++ FUN_001198-T1 97 ENMASLTDHDNTVSSVSVDCIKSKIVSGSWDRSIKEWDIEQEKC 140 44444488999*************************99965544 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0099 Beta-prop_NUP159_NUP214 64 vaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlkarslv...svl 146 v s +++l+++ edg+++ ++++ + +p+++ ++ + +l+ p + e la ++++ +++ d ++++v + + FUN_001198-T1 200 VDWSPLDHHLLAVGYEDGSVCLCNIQNPK----QPVLTYCHHERAVNKLAFSPRS-PEWLATVSDDMWVHVQDCLNDTTVlrsDEH 280 55666677899999999999999999999....99999999999*********96.89****************999999999999 PP Beta-prop_NUP159_NUP214 147 kenvssfdwsnkgkqlvvgladgtaqqlkp 176 +e v ++ws ++ l+ +++ ++ FUN_001198-T1 281 SEVVRGLAWSPVDDTLYTSGWGQQIFSHAF 310 999*******99999987666666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (381 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 708 (0.0277158); expected 510.9 (0.02) Passed bias filter: 497 (0.0194559); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 35 (0.00137013); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 35 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 3583.58 // Query: FUN_001199-T1 [L=112] Description: FUN_001199 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (112 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 538 (0.0210609); expected 510.9 (0.02) Passed bias filter: 349 (0.0136622); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1120.43 // Query: FUN_001200-T1 [L=223] Description: FUN_001200 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-34 116.6 3.8 1.1e-33 116.0 3.8 1.3 1 Ribosomal_L21p Ribosomal prokaryotic L21 protein Domain annotation for each model (and alignments): >> Ribosomal_L21p Ribosomal prokaryotic L21 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 116.0 3.8 4.1e-38 1.1e-33 2 99 .] 111 212 .. 110 212 .. 0.95 Alignments for each domain: == domain 1 score: 116.0 bits; conditional E-value: 4.1e-38 Ribosomal_L21p 2 yAiietgGkqykVeegdvlkvekleaevgdkveldkVllvg..devkvgaplveg..akVeaevvehgkgkkvivfkkkrrknyrrkqghRqelt 92 +A+i++gG+q+kV+ +d++ +++++a+ g++++++kVl++g ++ ++g+pl+ + k+ea+vve++k++kvivfkkkrrk+y+r+qghRq++t FUN_001200-T1 111 FAVIHIGGRQFKVTINDTIVINRIDADTGERIRIEKVLMIGgeNFSVIGTPLLVRdlSKIEATVVEKTKSPKVIVFKKKRRKGYKRTQGHRQDIT 205 9****************************************7444*******987567************************************* PP Ribosomal_L21p 93 klrIteI 99 +lrI++I FUN_001200-T1 206 VLRINSI 212 *****98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (223 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 646 (0.0252887); expected 510.9 (0.02) Passed bias filter: 461 (0.0180466); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2216.90 // Query: FUN_001201-T1 [L=402] Description: FUN_001201 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-23 82.2 0.0 6.7e-23 80.5 0.0 1.9 2 Abhydro_lipase Partial alpha/beta-hydrolase lipase region 6.9e-20 72.2 0.2 7.7e-19 68.8 0.2 2.0 1 Abhydrolase_1 alpha/beta hydrolase fold 1.6e-10 41.2 0.0 1.9e-08 34.4 0.0 2.2 2 Hydrolase_4 Serine aminopeptidase, S33 0.0041 18.3 0.0 0.011 16.8 0.0 1.7 1 Abhydrolase_6 Alpha/beta hydrolase family ------ inclusion threshold ------ 0.047 13.9 0.0 0.078 13.2 0.0 1.3 1 Esterase Putative esterase Domain annotation for each model (and alignments): >> Abhydro_lipase Partial alpha/beta-hydrolase lipase region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.5 0.0 1.3e-26 6.7e-23 1 62 [. 38 99 .. 38 100 .. 0.97 2 ? -2.6 0.0 1.1 5.7e+03 38 50 .. 274 286 .. 267 292 .. 0.79 Alignments for each domain: == domain 1 score: 80.5 bits; conditional E-value: 1.3e-26 Abhydro_lipase 1 vseiikkyGypveeheVtTeDGYiLtlhRipagrkksekkekkpvvllqHGLlasSeswvtn 62 v+eii++ Gy +eeh+VtT+DG+iL l+Rip+gr +++k+++k+vv+lqHG la++++wv+ FUN_001201-T1 38 VTEIIASRGYAFEEHYVTTQDGFILGLQRIPRGRSEESKNGGKQVVFLQHGFLADASTWVMD 99 689*********************************************************86 PP == domain 2 score: -2.6 bits; conditional E-value: 1.1 Abhydro_lipase 38 ekkekkpvvllqH 50 + +e++ +v++ H FUN_001201-T1 274 DINESRVPVYIAH 286 56778889**999 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.8 0.2 1.5e-22 7.7e-19 2 244 .. 82 382 .. 81 383 .. 0.80 Alignments for each domain: == domain 1 score: 68.8 bits; conditional E-value: 1.5e-22 Abhydrolase_1 2 pvlllHGlpg.....ssdlwrk.lapaLakdgfrvialDlrGfGkSsrpkaq............ddyrtddlaedlekildalglekvnlvGhSlG 79 +v l HG+++ +d+ + l++ La++gf+v++ + rG+++S+r+ ++ +dl ++++++l+ +g++++ +vGhS+G FUN_001201-T1 82 VVFLQHGFLAdastwVMDSATEsLGYILADSGFDVWLGNIRGNDYSRRHVKYlpnqhifwnwswQEMAHFDLPAMINYVLQVTGQKQLFYVGHSQG 177 7999******8865544445559***************************99****999999999999999************************* PP Abhydrolase_1 80 Glialayaaky...pervkalvllga.........lspaaeldeaarfilasfpgffdgfvadfarnrlgrlvakelallllrlrllkalpelskr 163 +lia++ +a++ +++ka+ l++ ++ +a+ + ++ ++ +fd + d++r+ + ++++ + + + +l+ +l++ FUN_001201-T1 178 TLIAFNGFADNpdlEKKIKAFFALAPvytlnnvtkIAQDAAAILYPLVKKLDPNLTFDLLPGDVFRALIELGFCAYPVEENICYDLV----QLVVG 269 ***********99999***********996666665555555555555566666778888888888888888888888888888875....56666 PP Abhydrolase_1 164 fpsedlalakslvtgallfletwstelrakllgrlde...............................ptlviwgeqDplvppqaleklaqlfpn. 227 + s+d++ + +v+ a+lf t + +++ + + pt+++ +++D+l +p +++l+ ++n FUN_001201-T1 270 MDSKDINESRVPVYIAHLFEGTSFKDVFHYAQMIFHRncqkfdygptgnkrhynqttaplcnvqgmptPTMMFVATEDKLGDPVDNAALKPQIKNl 365 66666666666666666666666666666666666556666666777777777777777************************6666666666666 PP Abhydrolase_1 228 arevvipdagHfafleg 244 + ++ i+++ H++fl g FUN_001201-T1 366 VHYEMIQGWNHLDFLYG 382 ************99875 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.4 0.0 3.7e-12 1.9e-08 4 138 .. 80 230 .. 78 249 .. 0.78 2 ! 4.6 0.0 0.0049 25 187 231 .. 333 376 .. 320 379 .. 0.81 Alignments for each domain: == domain 1 score: 34.4 bits; conditional E-value: 3.7e-12 Hydrolase_4 4 kavvvlvHGlg.ehsgr.....yaelaeaLaaqGfavyalDhrGhGkse.......gkrghvp.sfddy.vdDlaafvekikeehpglplfllGhS 84 k+vv+l HG+ + s + + l++ La+ Gf+v+ + rG s +++ ++ s++++ Dl a+++ + + +++lf +GhS FUN_001201-T1 80 KQVVFLQHGFLaDASTWvmdsaTESLGYILADSGFDVWLGNIRGNDYSRrhvkylpNQHIFWNwSWQEMaHFDLPAMINYVLQVTGQKQLFYVGHS 175 57788888875144443111114567889********************99999994444332255555156************************ PP Hydrolase_4 85 mGGaiallylleypd...kvkglilsaPalkikekvappllkllakllskllpklrv 138 G +ia++ +++pd k+k++ +aP++ +++ ++++++ +a +l l++kl + FUN_001201-T1 176 QGTLIAFNGFADNPDlekKIKAFFALAPVYTLNN--VTKIAQDAAAILYPLVKKLDP 230 **************9999*************996..677777777777777776655 PP == domain 2 score: 4.6 bits; conditional E-value: 0.0049 Hydrolase_4 187 ekitvPllllhGgaDkvvdpagsrelyeragskdktlklypglyH 231 + + +P++++++++Dk+ dp + +l +++ +++++++g+ H FUN_001201-T1 333 QGMPTPTMMFVATEDKLGDPVDNAALKPQIKN-LVHYEMIQGWNH 376 45569***************999998888885.788888888777 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 2.2e-06 0.011 1 186 [. 82 357 .. 82 388 .. 0.48 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 2.2e-06 Abhydrolase_6 1 vvlv.HGaglssssW..rl.vapL.aallaagvrvlapDlpGhGssdppp...........ldladvadl..adlldelga..gggpvvlvGHSlG 76 vv++ HG+ +++s W + +L l+++g+ v+ +G s++ ++++ a++ + + + + g ++ + vGHS G FUN_001201-T1 82 VVFLqHGFLADASTWvmDSaTESLgYILADSGFDVWLGNIRGNDYSRRHVkylpnqhifwnWSWQEMAHFdlPAMINYVLQvtGQKQLFYVGHSQG 177 79999**********5522355774445555588899999999633222255556666655444444444335555555555555888******** PP Abhydrolase_6 77 Gavala.aa.......lvag.vllap.......pvaplgllaallallaallaalaa.............pawlaaeslar.gflddtpadaawaa 142 ++a + a ++++ +lap + +++ +aa l +l++ + ++a l + gf++ +++ FUN_001201-T1 178 TLIAFNgFAdnpdlekKIKAfFALAPvytlnnvT--------KIAQDAAAILYPLVKkldpnltfdllpgDVFRA---LIElGFCAYPVE------ 256 ******8335788898778899999955554331........333333322222222121111101111111111...111122222221...... PP Abhydrolase_6 143 alarla.............................................................allaalallplaawadlpapvlvl.gteD 176 + ++ ++ pl ++ +p+p++++ +teD FUN_001201-T1 257 -----EnicydlvqlvvgmdskdinesrvpvyiahlfegtsfkdvfhyaqmifhrncqkfdygptgnKRHYNQTTAPLCNVQGMPTPTMMFvATED 347 .....0111111111112223333333333333333344444444444444455555444444443322223334456677777777733337777 PP Abhydrolase_6 177 rlvpelaqrl 186 +l +++ ++ FUN_001201-T1 348 KLGDPVDNAA 357 7555443333 PP >> Esterase Putative esterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 1.5e-05 0.078 19 145 .. 75 197 .. 66 211 .. 0.82 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1.5e-05 Esterase 19 spgrkypvlylldGl....tdwdqngrakellerlaaegeiaeviivgvprggessfyskwdlgarfyenategggaeayetflteeLlplldanf 110 s++++ v++l++G+ + w + ++++l + la++g + v + + + +ys++++ y++ + ++ +++ + L+ +++ + FUN_001201-T1 75 SKNGGKQVVFLQHGFladaSTWVMDSATESLGYILADSG-----FDVWLGNIRGN-DYSRRHVK---YLPNQHIFWNWSWQEMAHFDLPAMINYVL 161 678888999999999999888988888888888888886.....33444333333.47888888...99999999********************* PP Esterase 111 rtapdg.ralvGqSmGGlgALilalkypdlFgsvss 145 +++ ++ vG+S+G l+A +++pdl +++ + FUN_001201-T1 162 QVTGQKqLFYVGHSQGTLIAFNGFADNPDLEKKIKA 197 ****998889******************98666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 592 (0.0231748); expected 510.9 (0.02) Passed bias filter: 530 (0.0207477); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3940.38 // Query: FUN_001202-T1 [L=382] Description: FUN_001202 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-23 80.6 0.0 1.4e-22 79.4 0.0 1.6 2 Abhydro_lipase Partial alpha/beta-hydrolase lipase region 9.6e-22 78.3 0.2 2.3e-21 77.1 0.2 1.6 1 Abhydrolase_1 alpha/beta hydrolase fold 7.5e-14 52.1 0.0 1.4e-12 47.9 0.0 2.1 1 Hydrolase_4 Serine aminopeptidase, S33 ------ inclusion threshold ------ 0.033 14.5 0.1 0.63 10.3 0.0 2.4 2 Abhydrolase_5 Alpha/beta hydrolase family 0.034 14.7 0.0 0.067 13.8 0.0 1.4 1 DUF7962 Domain of unknown function (DUF7962) 0.093 12.7 0.0 0.13 12.2 0.0 1.2 1 Tle3 T6SS Tle3 phospholipase effector domain 0.095 13.8 0.0 0.2 12.7 0.0 1.7 1 Abhydrolase_6 Alpha/beta hydrolase family 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 Esterase Putative esterase Domain annotation for each model (and alignments): >> Abhydro_lipase Partial alpha/beta-hydrolase lipase region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.4 0.0 4.5e-26 1.4e-22 1 62 [. 40 101 .. 40 102 .. 0.97 2 ? -3.8 0.0 4.3 1.4e+04 39 50 .. 278 289 .. 274 289 .. 0.76 Alignments for each domain: == domain 1 score: 79.4 bits; conditional E-value: 4.5e-26 Abhydro_lipase 1 vseiikkyGypveeheVtTeDGYiLtlhRipagrkksekkekkpvvllqHGLlasSeswvtn 62 v++ii++ Gy +eeh V TeDG+iL ++Rip+gr+++++++ k+vv+lqHG+la++++w++ FUN_001202-T1 40 VTDIIASRGYAYEEHHVITEDGFILGMQRIPRGREEKRNSNDKQVVFLQHGILADATNWIMD 101 689*********************************************************85 PP == domain 2 score: -3.8 bits; conditional E-value: 4.3 Abhydro_lipase 39 kkekkpvvllqH 50 e++ +v++ H FUN_001202-T1 278 IDESRLPVYIAH 289 567788999999 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.1 0.2 7.2e-25 2.3e-21 2 244 .. 84 362 .. 83 363 .. 0.82 Alignments for each domain: == domain 1 score: 77.1 bits; conditional E-value: 7.2e-25 Abhydrolase_1 2 pvlllHGlpgssdlwrk......lapaLakdgfrvialDlrGfGkSsrpkaq............ddyrtddlaedlekildalglekvnlvGhSlG 79 +v l HG+++ +w+ +a+ La++gf+v++ ++rG+ +S+r+ ++ + dl ++++++l+ g++++ +vGhS+G FUN_001202-T1 84 VVFLQHGILADATNWIMdsasesFAYILADNGFDVWLGNVRGNVYSRRHVKYmpnqsifwnwswQEMADYDLPAMINYVLQVSGQKQLFYVGHSQG 179 7999******7777777777779***************************99************99****************************** PP Abhydrolase_1 80 Glialayaaky...pervkalvllgalspaaeldeaarfilasfpgffdgfvadfarnrlgrlvakelallllrlrllkal............... 157 ++ia++ +a++ +++ka+ l++ + l+ a + f+ f + + ++ +l++ ++ ++l+ l l+ l FUN_001202-T1 180 TMIAFNGFADNpdlGKKIKAFFALAP---VYTLNNATKIVKDAAKIFYPLFKKLDPNLTFDVLPGEFSVRSLTKLGLCGNLvtkkicyyimetmvg 272 ***********88889**********...44444444444444444444555555555555555555555555555555555666*****999998 PP Abhydrolase_1 158 .pelskrfpsedlalakslvtgallfletwstelrakllgrlde..ptlviwgeqDplvppqaleklaqlfpn.arevvipdagHfafleg 244 +++ ++ +++a+ + ++ + +++++++ ++ ++ + ptl++ +e+D + +p +e l++ ++n a ++vi ++ H++fl g FUN_001202-T1 273 mDSKNIDESRLPVYIAHFGEGTSFKDMVHFAQVTAPLCHVQG-MstPTLLFVAENDLIADPGDNEGLKKQIKNlAHYEVITGWNHLDFLYG 362 888888888888899999999999999999988885555444.469************************999999***********9875 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.9 0.0 4.5e-16 1.4e-12 4 231 .. 82 356 .. 79 360 .. 0.78 Alignments for each domain: == domain 1 score: 47.9 bits; conditional E-value: 4.5e-16 Hydrolase_4 4 kavvvlvHGlgehs.gry.....aelaeaLaaqGfavyalDhrGhGkse.......gkrghvp.sfddyvd.DlaafvekikeehpglplfllGhS 84 k+vv+l HG+ + +++ + +a+ La++Gf+v+ + rG s ++ ++ s++++ d Dl a+++ + + + +++lf +GhS FUN_001202-T1 82 KQVVFLQHGILADAtNWImdsasESFAYILADNGFDVWLGNVRGNVYSRrhvkympNQSIFWNwSWQEMADyDLPAMINYVLQVSGQKQLFYVGHS 177 67777777764443122211111559999********************888888744443333667776669*********************** PP Hydrolase_4 85 mGGaiallylleypd...kvkglilsaPalkikekvappllkllakllskllpklrv.................................snkldp 144 G +ia++ +++pd k+k++ +aP++ +++ a++++k +ak++ l++kl + +++ FUN_001202-T1 178 QGTMIAFNGFADNPDlgkKIKAFFALAPVYTLNN--ATKIVKDAAKIFYPLFKKLDPnltfdvlpgefsvrsltklglcgnlvtkkicyyIMETMV 271 ***************999**************97..5677777777777777777766677******************99987777666555566 PP Hydrolase_4 145 dslsrdpevvkayaaDplvhgkisvrlllellragerlekraekitvPllllhGgaDkvvdpagsrelyeragskdktlklypglyH 231 + s++ ++ + +++s + ++++ ++++ l +++ +++P+ll+++++D + dp + + l ++++ +++++ g+ H FUN_001202-T1 272 GMDSKNIDESRLPVYIAHFGEGTSFKDMVHFAQVTAPL-CHVQGMSTPTLLFVAENDLIADPGDNEGLKKQIKN-LAHYEVITGWNH 356 66666666666666666666777777777777776665.4555677*******************999999996.888888888888 PP >> Abhydrolase_5 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.12 3.8e+02 55 88 .. 167 204 .. 157 222 .. 0.65 2 ? 10.3 0.0 0.0002 0.63 82 148 .. 297 363 .. 285 367 .. 0.82 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.12 Abhydrolase_5 55 klekfvvgGhslGGvvasr.faaee...ekiegvvfla 88 ++++++ Ghs G ++a + fa + +ki++ + la FUN_001202-T1 167 GQKQLFYVGHSQGTMIAFNgFADNPdlgKKIKAFFALA 204 455666679****9988552666442323666666665 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0002 Abhydrolase_5 82 egvvflasYPe.kdelselskkvlsivgteDgvlnvkslekakkflpkdtkvvsieGgnhagfGsYGe 148 + +v++a + +++ +s+++l v+++D +++ + e kk++ + +++ +i G nh +f YG+ FUN_001202-T1 297 KDMVHFAQVTApLCHVQGMSTPTLLFVAENDLIADPGDNEGLKKQIKNLAHYEVITGWNHLDF-LYGK 363 566666655443456788999***************************************999.4665 PP >> DUF7962 Domain of unknown function (DUF7962) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 2.1e-05 0.067 33 92 .. 67 127 .. 57 146 .. 0.87 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 2.1e-05 DUF7962 33 eelekarpealaeiraafellettlLaDgreWilktekpslaDieavWplh.Wlaglkgal 92 +++ + r+e ++ +++ +l + +LaD +Wi+++ + s+a i a ++ Wl +++g + FUN_001202-T1 67 QRIPRGREEKRNSNDKQVVFLQHGILADATNWIMDSASESFAYILADNGFDvWLGNVRGNV 127 56778899999999999***************************99999877999988876 PP >> Tle3 T6SS Tle3 phospholipase effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 4.1e-05 0.13 101 198 .. 81 185 .. 43 221 .. 0.67 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 4.1e-05 Tle3 101 ldeekakgGGpFanattnlpdlwgegfkekllevllfl.lsvqalnedadrqlyeaPerk......YyvlAAkRLakLikeiRekeadetitivaH 189 ++ + + G +a+at+ ++d +e+f l++ + l + n +r+++ P++ ++ +A L ++i+ + + + ++ + v+H FUN_001202-T1 81 DKQVVFLQHGILADATNWIMDSASESFAYILADNGFDVwLGNVRGNVYSRRHVKYMPNQSifwnwsWQEMADYDLPAMINYVLQVSGQKQLFYVGH 176 344455666788888888888877777776655543333333345555666777777764222222566788889999****************** PP Tle3 190 SqGtliall 198 SqGt+ia FUN_001202-T1 177 SQGTMIAFN 185 ******975 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 6.4e-05 0.2 1 110 [. 84 229 .. 84 365 .. 0.56 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 6.4e-05 Abhydrolase_6 1 vvlv.HGaglssssW...rlvapLaallaag.vrvlapDlpGh..Gssdppp............ldladvadl..adlldelga..gggpvvlvGH 73 vv++ HG ++++ W +++ ++a la+ + v+ +G ++ + ++++ ad+ + + + + g ++ + vGH FUN_001202-T1 84 VVFLqHGILADATNWimdSASESFAYILADNgFDVWLGNVRGNvySRR---HvkympnqsifwnWSWQEMADYdlPAMINYVLQvsGQKQLFYVGH 176 788889999999999664224466555555557778777777754312...1234555566655666667777666677777776666777***** PP Abhydrolase_6 74 SlGGavala.aa.......lvag.vllappvaplgl........laallallaa 110 S G ++a + a ++++ +lap v+ l + + +l++ FUN_001202-T1 177 SQGTMIAFNgFAdnpdlgkKIKAfFALAP-VYTLNNatkivkdaAKIFYPLFKK 229 *********83357777877777888888.333333223322223333333333 PP >> Esterase Putative esterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 7.7e-05 0.25 24 146 .. 82 200 .. 69 214 .. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.7e-05 Esterase 24 ypvlylldGl....tdwdqngrakellerlaaegeiaeviivgvprggessfyskwdlgarfyenategggaeayetflteeLlplldanfrtapd 115 v++l++G+ t+w + + +++ + la+ g + + g rg++ ys++++ y + ++ ++ +++ L+ +++ ++++ + FUN_001202-T1 82 KQVVFLQHGIladaTNWIMDSASESFAYILADNG-F--DVWLGNVRGNV---YSRRHVK---YMPNQSIFWNWSWQEMADYDLPAMINYVLQVSGQ 168 5688888888677677777776666666565554.2..22233333333...6888877...88888889999999******************** PP Esterase 116 g.ralvGqSmGGlgALilalkypdlFgsvssf 146 + vG+S+G ++A +++pdl +++ +f FUN_001202-T1 169 KqLFYVGHSQGTMIAFNGFADNPDLGKKIKAF 200 98889******************987776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (382 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 581 (0.0227442); expected 510.9 (0.02) Passed bias filter: 521 (0.0203954); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.32u 0.44s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3640.75 // Query: FUN_001203-T1 [L=151] Description: FUN_001203 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (151 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 896 (0.0350754); expected 510.9 (0.02) Passed bias filter: 562 (0.0220004); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1507.26 // Query: FUN_001204-T1 [L=410] Description: FUN_001204 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-24 83.9 0.0 1.2e-23 82.9 0.0 1.6 1 Abhydro_lipase Partial alpha/beta-hydrolase lipase region 1.5e-20 74.4 0.1 1.9e-19 70.8 0.1 2.1 1 Abhydrolase_1 alpha/beta hydrolase fold 3e-12 46.9 0.0 1.9e-08 34.5 0.0 2.2 2 Hydrolase_4 Serine aminopeptidase, S33 0.0045 18.1 0.0 0.013 16.6 0.0 1.7 1 Abhydrolase_6 Alpha/beta hydrolase family 0.005 17.1 0.0 0.0086 16.4 0.0 1.3 1 Esterase Putative esterase ------ inclusion threshold ------ 0.12 12.5 0.0 0.59 10.3 0.0 1.9 2 Abhydrolase_11 Alpha/beta hydrolase domain 0.21 12.2 0.0 0.38 11.3 0.0 1.4 1 DUF7962 Domain of unknown function (DUF7962) Domain annotation for each model (and alignments): >> Abhydro_lipase Partial alpha/beta-hydrolase lipase region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.9 0.0 3.2e-27 1.2e-23 1 61 [. 40 100 .. 40 102 .. 0.97 Alignments for each domain: == domain 1 score: 82.9 bits; conditional E-value: 3.2e-27 Abhydro_lipase 1 vseiikkyGypveeheVtTeDGYiLtlhRipagrkksekkekkpvvllqHGLlasSeswvt 61 v+++i++ Gy++eeh VtTeDG+iL l+Rip+gr ++ ++e+kpvv+lqHG+l++S++wv+ FUN_001204-T1 40 VTQLIASRGYDYEEHHVTTEDGFILGLQRIPRGRGEKISSENKPVVFLQHGILEDSTNWVL 100 6899*******************************************************97 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.8 0.1 5.2e-23 1.9e-19 1 244 [. 83 384 .. 83 385 .. 0.76 Alignments for each domain: == domain 1 score: 70.8 bits; conditional E-value: 5.2e-23 Abhydrolase_1 1 ppvlllHGlpgssdlwrk......lapaLakdgfrvialDlrGfGkSsrpkaq............ddyrtddlaedlekildalglekvnlvGhSl 78 p+v l HG+++ s +w +a+ La++gf+v++ + rG+++S+r+ ++ + dl ++++++l+ g +++ +vGhS+ FUN_001204-T1 83 PVVFLQHGILEDSTNWVLdsasksFAYILADSGFDVWLGNIRGNDYSRRHVKYkpsqsifwnwswQEMADYDLPAMINYALQVSGEKQLFYVGHSQ 178 799********6666555555569***************************99************99***************************** PP Abhydrolase_1 79 GGlialayaaky...pervkalvllga.......lspaaeldeaarfilasfpgffdgfvadfarnrlgrlvakelallllrlrllkal....... 157 G++ia++ +a++ ++vka+ l++ + + s + ++ + + + ++ ++++ + +l + ++l FUN_001204-T1 179 GTMIAFNGFADNpnlGNKVKAFFALAPvytlngaT----------KIAKGSAELLYPLVKKLDPNLTFDVFPGEFFESLVKLGLCANPLsekvcyd 264 ************99999**********64444441..........444444444444444444444444444444444444444433334444554 PP Abhydrolase_1 158 ........pelskrfpsedlalakslvtgallfletwstelrakllgrlde........................ptlviwgeqDplvppqalekl 221 + + ++ ++ a+ + ++ ++++++ ++ +++++++d ptl++ ge+D+l +p +e+l FUN_001204-T1 265 lmelvvgmDSENIDQSRVPVYVAHFGEGTSFKNMVHFGQVIVNQKCQKFDYgptgnkrrynqttaplchvqdmptPTLMYVGEKDKLGDPVDNEAL 360 444446664444444444455555555555555555555555555555555888889*************************************** PP Abhydrolase_1 222 aqlfpn.arevvipdagHfafleg 244 + +++n + +++i ++ H++fl+g FUN_001204-T1 361 KPHIKNlVHYEIIKGWNHLDFLFG 384 *999999**************986 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.5 0.0 5.1e-12 1.9e-08 2 138 .. 80 232 .. 79 288 .. 0.82 2 ! 10.3 0.0 0.00012 0.43 185 231 .. 333 378 .. 324 382 .. 0.89 Alignments for each domain: == domain 1 score: 34.5 bits; conditional E-value: 5.1e-12 Hydrolase_4 2 epkavvvlvHGlgehsgr......yaelaeaLaaqGfavyalDhrGhGkse........gkrghvpsfddyvd.DlaafvekikeehpglplfllG 82 e+k vv+l HG+ e s + +a+ La+ Gf+v+ + rG s + s++++ d Dl a+++ + + + +++lf +G FUN_001204-T1 80 ENKPVVFLQHGILEDSTNwvldsaSKSFAYILADSGFDVWLGNIRGNDYSRrhvkykpsQSIFWNWSWQEMADyDLPAMINYALQVSGEKQLFYVG 175 6788999999999998642222214679***********************99999985333333467777766********************** PP Hydrolase_4 83 hSmGGaiallylleypd...kvkglilsaPalkikekvappllkllakllskllpklrv 138 hS G +ia++ +++p+ kvk++ +aP++ ++ a++++k a+ll l++kl + FUN_001204-T1 176 HSQGTMIAFNGFADNPNlgnKVKAFFALAPVYTLNG--ATKIAKGSAELLYPLVKKLDP 232 ****************9999************9995..788888888888888888876 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00012 Hydrolase_4 185 raekitvPllllhGgaDkvvdpagsrelyeragskdktlklypglyH 231 +++++ +P+l+++G++Dk+ dp + ++l +++ +++++++g+ H FUN_001204-T1 333 HVQDMPTPTLMYVGEKDKLGDPVDNEALKPHIKN-LVHYEIIKGWNH 378 667888************************9996.999999999999 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 3.7e-06 0.013 1 206 [. 84 380 .. 84 388 .. 0.55 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 3.7e-06 Abhydrolase_6 1 vvlv.HGaglssssW...rlvapLaallaag.vrvlapDlpGhGssdppp...........ldladvadl..adlldelga..gggpvvlvGHSlG 76 vv++ HG +s+ W +++ ++a la+ + v+ +G s++ ++++ ad+ + + + g ++ + vGHS G FUN_001204-T1 84 VVFLqHGILEDSTNWvldSASKSFAYILADSgFDVWLGNIRGNDYSRRHVkykpsqsifwnWSWQEMADYdlPAMINYALQvsGEKQLFYVGHSQG 179 7888899888899995532233443333444477788888888533222244555555555455555555544444444445556888******** PP Abhydrolase_6 77 Gavala.aa.......lvag.vllappvaplgllaallallaallaalaa.....pawlaaeslargflddtp.......adaawaaalarla... 148 ++a + a +v++ +lap v+ l ++ +++ a ll +l++ +++ +++ +f++ ++ + FUN_001204-T1 180 TMIAFNgFAdnpnlgnKVKAfFALAP-VYTLNGATKIAKGSAELLYPLVKkldpnLTFDV--FPG-EFFESLVklglcanP-----------Lsek 260 ******833577888888999*****.444444333333333333322222221222222..122.444433322111110...........0122 PP Abhydrolase_6 149 ............................................................allaalallplaawadlpapv..lvlgteDrlvpel 182 + ++ ++ pl ++ d+p+p+ +v g++D+l +++ FUN_001204-T1 261 vcydlmelvvgmdsenidqsrvpvyvahfgegtsfknmvhfgqvivnqkcqkfdygptgnKRRYNQTTAPLCHVQDMPTPTlmYV-GEKDKLGDPV 355 2222223333344445555555566666677778888888888888888887777766654444555667889999999994222.7888855555 PP Abhydrolase_6 183 aqrllaa..lagarlpvvlpgaGHlp 206 ++l+ + +++ +++ g +Hl FUN_001204-T1 356 DNEALKPhiKNLVHY-EIIKGWNHLD 380 444444322255555.7788888854 PP >> Esterase Putative esterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 2.4e-06 0.0086 22 146 .. 80 200 .. 74 217 .. 0.86 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 2.4e-06 Esterase 22 rkypvlylldGl....tdwdqngrakellerlaaegeiaeviivgvprggessfyskwdlgarfyenategggaeayetflteeLlplldanfrta 113 ++ pv++l++G+ t+w + + k++ + la++g + v + + + +ys++++ y++ ++ ++ +++ L+ +++ ++++ FUN_001204-T1 80 ENKPVVFLQHGIledsTNWVLDSASKSFAYILADSG-----FDVWLGNIRGN-DYSRRHVK---YKPSQSIFWNWSWQEMADYDLPAMINYALQVS 166 678*********9****************9999997.....33444433333.47889888...99999999************************ PP Esterase 114 pdg.ralvGqSmGGlgALilalkypdlFgsvssf 146 ++ vG+S+G ++A +++p+l +v +f FUN_001204-T1 167 GEKqLFYVGHSQGTMIAFNGFADNPNLGNKVKAF 200 **98889******************987777665 PP >> Abhydrolase_11 Alpha/beta hydrolase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.42 1.5e+03 70 105 .. 164 203 .. 150 218 .. 0.72 2 ? 10.3 0.0 0.00016 0.59 120 165 .. 331 378 .. 314 389 .. 0.83 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.42 Abhydrolase_11 70 alleadkplvigGkSmGgRvAsllaaes.....kvkgvial 105 ++ + +k+l+ G S G +A+ a++ kvk+++al FUN_001204-T1 164 QV-SGEKQLFYVGHSQGTMIAFNGFADNpnlgnKVKAFFAL 203 33.55778999********9998775554555566666555 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00016 Abhydrolase_11 120 lehlkelsvpllivqGerDklgkkeevaal..klsenvklewledgdH 165 l h++++ +p+l+ Ge+Dklg+ + +al ++++ v++e++++ +H FUN_001204-T1 331 LCHVQDMPTPTLMYVGEKDKLGDPVDNEALkpHIKNLVHYEIIKGWNH 378 56999*****************98777777546777788999988888 PP >> DUF7962 Domain of unknown function (DUF7962) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.0001 0.38 33 90 .. 67 125 .. 55 142 .. 0.88 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0001 DUF7962 33 eelekarpealaeiraafellettlLaDgreWilktekpslaDieavWplh.Wlaglkg 90 +++ + r e + + ++ + +l + +L D+ +W+l++ + s+a i a ++ Wl +++g FUN_001204-T1 67 QRIPRGRGEKISSENKPVVFLQHGILEDSTNWVLDSASKSFAYILADSGFDvWLGNIRG 125 56788999999999999*************************99998877768877776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (410 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 584 (0.0228616); expected 510.9 (0.02) Passed bias filter: 548 (0.0214523); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 4063.81 // Query: FUN_001205-T1 [L=412] Description: FUN_001205 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-23 81.0 0.0 1.6e-22 79.3 0.0 1.9 2 Abhydro_lipase Partial alpha/beta-hydrolase lipase region 8.5e-21 75.2 0.3 5e-20 72.7 0.3 2.0 1 Abhydrolase_1 alpha/beta hydrolase fold 2.4e-11 43.9 0.0 2.9e-06 27.3 0.0 2.2 2 Hydrolase_4 Serine aminopeptidase, S33 ------ inclusion threshold ------ 0.029 15.5 0.0 0.077 14.1 0.0 1.7 1 Abhydrolase_6 Alpha/beta hydrolase family 0.098 13.9 0.0 0.19 13.0 0.0 1.4 1 RBR RNA binding Region Domain annotation for each model (and alignments): >> Abhydro_lipase Partial alpha/beta-hydrolase lipase region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.3 0.0 3.1e-26 1.6e-22 1 61 [. 38 98 .. 38 100 .. 0.97 2 ? -2.2 0.0 0.84 4.3e+03 38 50 .. 274 286 .. 269 286 .. 0.76 Alignments for each domain: == domain 1 score: 79.3 bits; conditional E-value: 3.1e-26 Abhydro_lipase 1 vseiikkyGypveeheVtTeDGYiLtlhRipagrkksekkekkpvvllqHGLlasSeswvt 61 v+eii++ Gy++eeh VtT+DG+iL l+Rip+gr ++++ ++kp+v+lqHG+la++++wv+ FUN_001205-T1 38 VTEIIASRGYTYEEHHVTTQDGFILGLQRIPRGRGEKNGIKHKPIVFLQHGILADASNWVL 98 689********************************************************97 PP == domain 2 score: -2.2 bits; conditional E-value: 0.84 Abhydro_lipase 38 ekkekkpvvllqH 50 + +++ +v+l H FUN_001205-T1 274 NIDKSRGPVYLAH 286 55677888***99 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.7 0.3 9.8e-24 5e-20 1 244 [. 81 382 .. 81 383 .. 0.82 Alignments for each domain: == domain 1 score: 72.7 bits; conditional E-value: 9.8e-24 Abhydrolase_1 1 ppvlllHGlpg.....ssdlwrk.lapaLakdgfrvialDlrGfGkSsrpkaq............ddyrtddlaedlekildalglekvnlvGhSl 78 p v l HG+++ + + r+ l++ La++gf+v++ ++rG+++S r+ ++ + dl ++++++l +g +++ +vGhS+ FUN_001205-T1 81 PIVFLQHGILAdasnwVLGSSREsLGYILADNGFDVWLGNVRGNDYSMRHVKYkpsqsvfwnwswQEMADYDLPAMINYVLHVTGKKQLFYVGHSQ 176 7899*******6554433445559***************************99************99***************************** PP Abhydrolase_1 79 GGlialayaaky...pervkalvllga.........lspaaeldeaarfilasfpgffdgfvadfarnrlgrlvakelallllrlrllkal..... 157 G++ia++ ++++ ++vka+ l++ + + + + + +++ fd+ + df+ +++ + + FUN_001205-T1 177 GTMIAFNGFSNNlalGNKVKAFFALAPvytlnnttkVVKGLAEIMWSVVKKFNPNLNFDTLPGDFFKSLVKLGYCANA------------Isekfc 260 ***************************666443332222222333333333344444444444444444444444444............334445 PP Abhydrolase_1 158 ..........pelskrfpsedlalakslvtgallfletwstelrakllgrlde........................ptlviwgeqDplvpp.qal 218 +++ +++ ++la+ + ++ ++++++s+ +++++d ptl++ g++D l +p +++ FUN_001205-T1 261 eylsgsvfgmDSKNIDKSRGPVYLAHFGEGTSFKNMVHFSQIIVEGKCQKFDYgptgnekhynqtspplcrvqnmrtPTLMFVGGNDGLGDPsDNK 356 5555666999*******************************9999999999999**************************************6666 PP Abhydrolase_1 219 eklaqlfpnarevvipdagHfafleg 244 + q+ + + ++vip++ H +fl g FUN_001205-T1 357 ALEPQIKNLVHYEVIPGWNHVDFLYG 382 666666666*************9875 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.0 5.7e-10 2.9e-06 3 138 .. 79 230 .. 77 247 .. 0.74 2 ! 14.5 0.0 4.6e-06 0.024 185 231 .. 331 376 .. 323 380 .. 0.93 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 5.7e-10 Hydrolase_4 3 pkavvvlvHGl.gehsgry.....aelaeaLaaqGfavyalDhrGhGkse.......gkrghvp.sfddyvd.DlaafvekikeehpglplfllGh 83 +k +v+l HG+ ++ s+++ + l++ La++Gf+v+ + rG s + + ++ s++++ d Dl a+++ + +++lf +Gh FUN_001205-T1 79 HKPIVFLQHGIlADASNWVlgssrESLGYILADNGFDVWLGNVRGNDYSMrhvkykpSQSVFWNwSWQEMADyDLPAMINYVLHVTGKKQLFYVGH 174 566777777752344443322222459999********************999999844444433677777669********************** PP Hydrolase_4 84 SmGGaiallylleypd...kvkglilsaPalkikekvappllkllakllskllpklrv 138 S G +ia++ ++ + kvk++ +aP++ +++ ++++k la+++ ++++k+ + FUN_001205-T1 175 SQGTMIAFNGFSNNLAlgnKVKAFFALAPVYTLNNT--TKVVKGLAEIMWSVVKKFNP 230 *********99555544559*************976..55555555555555555544 PP == domain 2 score: 14.5 bits; conditional E-value: 4.6e-06 Hydrolase_4 185 raekitvPllllhGgaDkvvdpagsrelyeragskdktlklypglyH 231 r++++++P+l+++Gg+D + dp++ ++l +++ ++++++pg+ H FUN_001205-T1 331 RVQNMRTPTLMFVGGNDGLGDPSDNKALEPQIKN-LVHYEVIPGWNH 376 78999***************************96.9********999 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.0 1.5e-05 0.077 1 113 [. 82 230 .. 82 385 .. 0.57 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.5e-05 Abhydrolase_6 1 vvlv.HGaglssssW....rlvapLaallaag.vrvlapDlpGhG.........ssdppp......ldladvadl..adlldelga..gggpvvlv 71 +v++ HG +++s W + +L la+ + v+ +G + + ++++ ad+ + + + g+++ + v FUN_001205-T1 82 IVFLqHGILADASNWvlgsS-RESLGYILADNgFDVWLGNVRGNDysmrhvkykP----SqsvfwnWSWQEMADYdlPAMINYVLHvtGKKQLFYV 172 799999*99999***44320.4477444444458888888888864455544442....0344444444445666554444444445567888*** PP Abhydrolase_6 72 GHSlGGavala.....aa...lvag.vllap.......pvaplgllaallallaalla 113 GHS G ++a + +a +v++ +lap + + gl+ ++ ++ +++ FUN_001205-T1 173 GHSQGTMIAFNgfsnnLAlgnKVKAfFALAPvytlnntTKVVKGLAEIMWSVVKKFNP 230 ***********87766337888788899999555555522223334444444444433 PP >> RBR RNA binding Region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 3.7e-05 0.19 36 56 .. 65 85 .. 52 86 .. 0.91 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 3.7e-05 RBR 36 vkipKKrGpKpGsKrKprpll 56 ++ip+ rG K G K Kp+++l FUN_001205-T1 65 QRIPRGRGEKNGIKHKPIVFL 85 68****************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (412 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 600 (0.023488); expected 510.9 (0.02) Passed bias filter: 546 (0.021374); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4035.55 // Query: FUN_001206-T1 [L=134] Description: FUN_001206 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 13.0 5.2 0.23 12.2 5.2 1.5 1 Toxin_8 Alpha conotoxin precursor 0.16 13.0 1.2 1.1 10.4 0.2 2.1 2 DUF3139 Protein of unknown function (DUF3139) Domain annotation for each model (and alignments): >> Toxin_8 Alpha conotoxin precursor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 5.2 1.8e-05 0.23 31 49 .. 71 88 .. 57 90 .. 0.85 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.8e-05 Toxin_8 31 vrkgCCsnPaCrvsnpelC 49 r +CC+ P+C+ +n e C FUN_001206-T1 71 CR-QCCQTPPCWYKNHEKC 88 45.9************999 PP >> DUF3139 Protein of unknown function (DUF3139) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 0.051 6.5e+02 5 17 .. 13 25 .. 5 48 .. 0.64 2 ? 10.4 0.2 8.4e-05 1.1 23 64 .. 81 125 .. 72 131 .. 0.85 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.051 DUF3139 5 kiiliiliilivi 17 i ++++++ +vi FUN_001206-T1 13 SIAMLVVVACVVI 25 3334444444433 PP == domain 2 score: 10.4 bits; conditional E-value: 8.4e-05 DUF3139 23 lyvkhkpiqkylgn...kkldkylqeqgikeddIksikakydikk 64 +y +h + +k lg+ k++++ l + ++k++ I +ik++++ k+ FUN_001206-T1 81 WYKNHEKCNKCLGKktkKNVSRLLRISHNKSKTIATIKSEKSGKR 125 677788888888877779**********************98776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1877 (0.0734782); expected 510.9 (0.02) Passed bias filter: 757 (0.029634); expected 510.9 (0.02) Passed Vit filter: 74 (0.00289685); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1348.87 // Query: FUN_001207-T1 [L=533] Description: FUN_001207 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-153 511.3 17.1 4e-153 511.1 17.1 1.0 1 Cpn60_TCP1 TCP-1/cpn60 chaperonin family ------ inclusion threshold ------ 0.013 15.3 0.1 0.047 13.5 0.0 1.9 2 MMM1 Maintenance of mitochondrial morphology protein 1 Domain annotation for each model (and alignments): >> Cpn60_TCP1 TCP-1/cpn60 chaperonin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 511.1 17.1 3.1e-157 4e-153 2 488 .. 34 522 .. 33 523 .. 0.97 Alignments for each domain: == domain 1 score: 511.1 bits; conditional E-value: 3.1e-157 Cpn60_TCP1 2 aelvktslGPkGmdKmlvn..kggkvtvTnDGatIlkelevehPaakllveaakaqdeevGDGTttvvvLageLleeaeklleagvhpttIiegye 95 +l+k++lGPkGmdK+l++ k++++ vTnDGatIlk++ v++Paak+lve++k qd+evGDGTt+v vLa+eLl+eaekl++ +vhp+ I++g++ FUN_001207-T1 34 GDLIKSTLGPKGMDKILQSfsKNEEIQVTNDGATILKSIGVDNPAAKILVELSKVQDNEVGDGTTSVTVLACELLREAEKLVSCKVHPQIIVSGWR 129 689***************9999************************************************************************** PP Cpn60_TCP1 96 kAlekaleiLksieieve...ekdreellkvartslsskvveeekerlaelvvdAvlaiekeekeldlenikvvklkggsledselveGvvldkev 188 k ++ a e+L+ +++++ ek +e+l+++art+lssk++ ++++++a+l+v+Avl ++ + +l+ i+++k+ gg+l ds l eG++ldk++ FUN_001207-T1 130 KSVHVAQEALEAAAVDHSgdeEKFKEDLMNIARTTLSSKILVQHRDHFANLAVEAVLRLKG---SGNLDAIQIIKKLGGNLVDSYLDEGFLLDKKI 222 **********88855554446889********************************88764...58*****************************9 PP Cpn60_TCP1 189 lseqmpkklenakilllnvsleiektet.kakvllssaeeleellkaeeeileekvkkiiesgvnvvvcqkgIddlalhflakngilalrrvkkkd 283 + +pk++e+akil+ n++++++k ++ + v+++s +++el+ ae+++++ekv+ i ++ ++++++++ I ++ ++++a++g++a+++++ + FUN_001207-T1 223 GVN-QPKRMEDAKILIANTAMDTDKIKVfGSRVRVESTGKVAELELAEKQKMKEKVDMILKHNITCFINRQLIYNYPEQLFADAGVMAIEHADFEG 317 987.5*********************988999**************************************************************** PP Cpn60_TCP1 284 lerlakatGarivsslddlteeelGkakkveeeeigeekvtiiegvkekkaatillrGatdevldelersveDAlnvvknaledervvpGGGavel 379 +erla ++G++ivs++++++ +lG++k +ee++ige+k+++++g+k ++a+ti++rGat+++lde++rs++DAl+v+ +++++ r v GGGa+e+ FUN_001207-T1 318 VERLALVLGGEIVSTFGHPELVNLGECKVIEEVMIGEDKLIHFSGCKLNEACTIVIRGATQQILDEADRSLHDALCVLTQTVKETRTVCGGGASEM 413 ************************************************************************************************ PP Cpn60_TCP1 380 elakkLreyaksvsgkeqlaieafaeALevipktLaeNaGldpievlakLraahakgekeagvdvesgeiidmleagvvdplkvkrqalksAteaA 475 +a ++++ a +++gke+ a+eafa AL+++p ++a NaG+d+ +++akLraah +g+k++g+d+ +g+i+dm+e gv ++++vk+q+l sA+eaA FUN_001207-T1 414 LMANAVSQLAAKTPGKEAAAMEAFAAALRQLPTIIADNAGYDSADLVAKLRAAHTEGKKTYGLDMINGRIGDMVEMGVTESYQVKKQVLVSAAEAA 509 ************************************************************************************************ PP Cpn60_TCP1 476 ttiLriDeiikak 488 ++i+r+D+i+ka FUN_001207-T1 510 EMIVRVDNIVKAA 522 **********986 PP >> MMM1 Maintenance of mitochondrial morphology protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 3.7e-06 0.047 73 128 .. 251 306 .. 225 328 .. 0.83 2 ? -1.6 0.0 0.15 1.9e+03 67 87 .. 347 368 .. 335 398 .. 0.73 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 3.7e-06 MMM1 73 GddfPifsncrikeskesekkrleakidvdlsdrltlgietklllnyPkpltavlP 128 G + s ++ e + +ek++++ k+d+ l+ ++t i+ +l+ nyP +l+a FUN_001207-T1 251 GSRVRVESTGKVAELELAEKQKMKEKVDMILKHNITCFINRQLIYNYPEQLFADAG 306 5555566777788889999******************************9998655 PP == domain 2 score: -1.6 bits; conditional E-value: 0.15 MMM1 67 iteidiGddfPi.fsncrikes 87 i e+ iG+d i fs c+++e+ FUN_001207-T1 347 IEEVMIGEDKLIhFSGCKLNEA 368 5689999987776999*99654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (533 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1118 (0.0437659); expected 510.9 (0.02) Passed bias filter: 778 (0.0304561); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5069.91 // Query: FUN_001207-T2 [L=488] Description: FUN_001207 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-145 485.0 18.0 3.6e-145 484.9 18.0 1.0 1 Cpn60_TCP1 TCP-1/cpn60 chaperonin family ------ inclusion threshold ------ 0.011 15.6 0.1 0.041 13.7 0.0 1.9 2 MMM1 Maintenance of mitochondrial morphology protein 1 Domain annotation for each model (and alignments): >> Cpn60_TCP1 TCP-1/cpn60 chaperonin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 484.9 18.0 2.8e-149 3.6e-145 14 488 .. 1 477 [. 1 478 [. 0.98 Alignments for each domain: == domain 1 score: 484.9 bits; conditional E-value: 2.8e-149 Cpn60_TCP1 14 mdKmlvn..kggkvtvTnDGatIlkelevehPaakllveaakaqdeevGDGTttvvvLageLleeaeklleagvhpttIiegyekAlekaleiLks 107 mdK+l++ k++++ vTnDGatIlk++ v++Paak+lve++k qd+evGDGTt+v vLa+eLl+eaekl++ +vhp+ I++g++k ++ a e+L+ FUN_001207-T2 1 MDKILQSfsKNEEIQVTNDGATILKSIGVDNPAAKILVELSKVQDNEVGDGTTSVTVLACELLREAEKLVSCKVHPQIIVSGWRKSVHVAQEALEA 96 89****9989************************************************************************************88 PP Cpn60_TCP1 108 ieieve...ekdreellkvartslsskvveeekerlaelvvdAvlaiekeekeldlenikvvklkggsledselveGvvldkevlseqmpkklena 200 +++++ ek +e+l+++art+lssk++ ++++++a+l+v+Avl ++ + +l+ i+++k+ gg+l ds l eG++ldk++ + +pk++e+a FUN_001207-T2 97 AAVDHSgdeEKFKEDLMNIARTTLSSKILVQHRDHFANLAVEAVLRLKG---SGNLDAIQIIKKLGGNLVDSYLDEGFLLDKKIGVN-QPKRMEDA 188 855554446889********************************88764...58*****************************9987.5******* PP Cpn60_TCP1 201 killlnvsleiektet.kakvllssaeeleellkaeeeileekvkkiiesgvnvvvcqkgIddlalhflakngilalrrvkkkdlerlakatGari 295 kil+ n++++++k ++ + v+++s +++el+ ae+++++ekv+ i ++ ++++++++ I ++ ++++a++g++a+++++ + +erla ++G++i FUN_001207-T2 189 KILIANTAMDTDKIKVfGSRVRVESTGKVAELELAEKQKMKEKVDMILKHNITCFINRQLIYNYPEQLFADAGVMAIEHADFEGVERLALVLGGEI 284 **************988999**************************************************************************** PP Cpn60_TCP1 296 vsslddlteeelGkakkveeeeigeekvtiiegvkekkaatillrGatdevldelersveDAlnvvknaledervvpGGGavelelakkLreyaks 391 vs++++++ +lG++k +ee++ige+k+++++g+k ++a+ti++rGat+++lde++rs++DAl+v+ +++++ r v GGGa+e+ +a ++++ a + FUN_001207-T2 285 VSTFGHPELVNLGECKVIEEVMIGEDKLIHFSGCKLNEACTIVIRGATQQILDEADRSLHDALCVLTQTVKETRTVCGGGASEMLMANAVSQLAAK 380 ************************************************************************************************ PP Cpn60_TCP1 392 vsgkeqlaieafaeALevipktLaeNaGldpievlakLraahakgekeagvdvesgeiidmleagvvdplkvkrqalksAteaAttiLriDeiika 487 ++gke+ a+eafa AL+++p ++a NaG+d+ +++akLraah +g+k++g+d+ +g+i+dm+e gv ++++vk+q+l sA+eaA++i+r+D+i+ka FUN_001207-T2 381 TPGKEAAAMEAFAAALRQLPTIIADNAGYDSADLVAKLRAAHTEGKKTYGLDMINGRIGDMVEMGVTESYQVKKQVLVSAAEAAEMIVRVDNIVKA 476 **********************************************************************************************98 PP Cpn60_TCP1 488 k 488 FUN_001207-T2 477 A 477 6 PP >> MMM1 Maintenance of mitochondrial morphology protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 3.2e-06 0.041 73 128 .. 206 261 .. 180 285 .. 0.83 2 ? -1.4 0.0 0.13 1.6e+03 67 87 .. 302 323 .. 289 353 .. 0.73 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.2e-06 MMM1 73 GddfPifsncrikeskesekkrleakidvdlsdrltlgietklllnyPkpltavlP 128 G + s ++ e + +ek++++ k+d+ l+ ++t i+ +l+ nyP +l+a FUN_001207-T2 206 GSRVRVESTGKVAELELAEKQKMKEKVDMILKHNITCFINRQLIYNYPEQLFADAG 261 5555566777788889999******************************9998655 PP == domain 2 score: -1.4 bits; conditional E-value: 0.13 MMM1 67 iteidiGddfPi.fsncrikes 87 i e+ iG+d i fs c+++e+ FUN_001207-T2 302 IEEVMIGEDKLIhFSGCKLNEA 323 5689999987776999*99654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (488 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 979 (0.0383245); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4636.33 // Query: FUN_001208-T1 [L=216] Description: FUN_001208 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-57 192.6 0.2 5.4e-57 192.4 0.2 1.0 1 Ras Ras family 7.4e-36 123.5 0.2 2.4e-35 121.8 0.1 1.8 2 Roc Ras of Complex, Roc, domain of DAPkinase 8.4e-14 51.9 0.2 1e-13 51.6 0.2 1.1 1 Arf ADP-ribosylation factor family 2.7e-05 24.3 0.1 5.1e-05 23.4 0.0 1.3 1 GTP_EFTU Elongation factor Tu GTP binding domain 0.00022 21.6 0.2 0.024 14.9 0.1 2.2 2 RsgA_GTPase RsgA GTPase 0.00096 19.1 0.0 0.0012 18.8 0.0 1.2 1 Gtr1_RagA Gtr1/RagA G protein conserved region 0.0013 19.3 0.0 0.0023 18.5 0.0 1.4 1 MMR_HSR1 50S ribosome-binding GTPase ------ inclusion threshold ------ 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 LigD_Prim-Pol LigD, primase-polymerase domain 0.031 14.5 0.3 0.19 12.0 0.3 2.0 1 PduV-EutP Ethanolamine utilisation - propanediol utilisa 0.046 14.5 0.0 1.7 9.4 0.0 2.2 2 AAA_22 AAA domain 0.18 12.3 0.3 3.1 8.3 0.1 2.5 2 AAA_14 AAA domain Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 192.4 0.2 2.3e-60 5.4e-57 1 161 [. 11 171 .. 11 172 .. 0.99 Alignments for each domain: == domain 1 score: 192.4 bits; conditional E-value: 2.3e-60 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwlee 96 k+vl+G+++vGK+sl+lr+v++kF++++ +T+ + f +k++++dg++v++ iwDTAGqerf+al + yyr+++g++lvydit+e+sf +vkkw++e FUN_001208-T1 11 KVVLLGEGCVGKTSLMLRYVQDKFNDKHLTTLQASFLNKRLNIDGQRVNIAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFFKVKKWVKE 106 89********************************************************************************************** PP Ras 97 ikrvaeenvpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 +k++ e++++++ Gnk+Dle++r+v+++e+ ++ak +g+k++ tSAk ++++ee+f el++++l FUN_001208-T1 107 LKKMLGEDIALCIAGNKIDLEKDRHVDAAEADAYAKTVGAKHFHTSAKLNKGIEEMFFELTKKML 171 *************************************************************9986 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 121.8 0.1 1e-38 2.4e-35 1 119 [] 11 125 .. 11 125 .. 0.92 2 ? -1.0 0.0 1.2 2.8e+03 18 42 .. 130 154 .. 129 166 .. 0.70 Alignments for each domain: == domain 1 score: 121.8 bits; conditional E-value: 1e-38 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srsse 93 KvvllG+++vGKtsl+ r+v+d+f++k+ +t++++fl+k+l +i+g +++++ iWDtaGqerf++l p+yyr++++ailv+d ++s+ FUN_001208-T1 11 KVVLLGEGCVGKTSLMLRYVQDKFNDKHLTTLQASFLNKRL-NIDG-------QRVNIAIWDTAGQERFHALGPIYYRDSNGAILVYDitdEDSFF 98 9**************************************98.6766.......5799******************************986566788 PP Roc 94 nlkeWlkelkevagkspvi.lvgnkiD 119 ++k+W+kelk++ g+++ + + gnkiD FUN_001208-T1 99 KVKKWVKELKKMLGEDIALcIAGNKID 125 9***********98876542899***9 PP == domain 2 score: -1.0 bits; conditional E-value: 1.2 Roc 18 rfvedefdekekstigvdflskelt 42 r+v+ + + +t+g++ ++ +++ FUN_001208-T1 130 RHVDAAEADAYAKTVGAKHFHTSAK 154 5666777788999999998876653 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.6 0.2 4.3e-17 1e-13 10 171 .. 5 167 .. 1 170 [. 0.79 Alignments for each domain: == domain 1 score: 51.6 bits; conditional E-value: 4.3e-17 Arf 10 lkkkelrilllGLDnaGKtTilkklkleelvt.tiPTi..gfnveevei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleea 100 ++k++++++llG + GKt ++ ++ ++++++ + T+ f ++++i + +++ +wD Gqe+ l Y+++ ++ i v D +d++ + + FUN_001208-T1 5 SRKNQFKVVLLGEGCVGKTSLMLRYVQDKFNDkHLTTLqaSFLNKRLNIdgQRVNIAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFFKV 100 457899*******************9999987344444225667777775578999***********************************87776 PP Arf 101 k...eeLkalleeeelkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkeglewls 171 k +eLk++l e ++al + +NK+Dl+++ + + ++ +++ ++++ ++sa ++g++e + l+ FUN_001208-T1 101 KkwvKELKKMLGE----DIALCIAGNKIDLEKDRHVDAAEADAYAKTVGAKHF---HTSAKLNKGIEEMFFELT 167 6111566666665....699************999988888888877777664...577777777777766665 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 2.2e-08 5.1e-05 62 182 .. 51 166 .. 38 173 .. 0.82 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 2.2e-08 GTP_EFTU 62 vsfetkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveG....vepqteevlrlarklgvpiivviNKmDrvdeaelkevveevkeellek 153 ++++++ +i++ Dt G + F ++ +ga+lv d+++ ++ + l+ + +++ ++++ NK+D+ ++ ++ ++++ + FUN_001208-T1 51 LNIDGQRVNIAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEdsffKVKKWVKELKKMLGEDIALCIAGNKIDLEKDRHVDAAEADAYAKT--- 143 56679999**********************************999998555666678889999**************8888888888888666... PP GTP_EFTU 154 vgekgekevpvvpgSalkgegvkelleal 182 vg + +++Sa+ ++g++e++ l FUN_001208-T1 144 VG------AKHFHTSAKLNKGIEEMFFEL 166 23......346899999999999865444 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.014 34 109 128 .. 12 31 .. 4 45 .. 0.82 2 ! 14.9 0.1 1e-05 0.024 37 108 .. 98 170 .. 82 172 .. 0.83 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.014 RsgA_GTPase 109 tvllGqSGvGKStLinallp 128 +vllG+ vGK++L+ + ++ FUN_001208-T1 12 VVLLGEGCVGKTSLMLRYVQ 31 79************977665 PP == domain 2 score: 14.9 bits; conditional E-value: 1e-05 RsgA_GTPase 37 fnlrlldrfLvlaeesgiepvivlnKiDlleeee.eleelkkeyealgyevllvsaktgegleelkellkgkt 108 f+++ + L + ++i i nKiDl ++++ +++e ++ ++++g + + +sak ++g+ee+ +l++k+ FUN_001208-T1 98 FKVKKWVKELKKMLGEDIALCIAGNKIDLEKDRHvDAAEADAYAKTVGAKHFHTSAKLNKGIEEMFFELTKKM 170 555566667777888999***************9888888899999*******************99999876 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 5.3e-07 0.0012 1 130 [. 11 133 .. 11 164 .. 0.71 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 5.3e-07 Gtr1_RagA 1 kvLLmGksksGKsS.irsviFsnyspkdtlrlgatidveksevrflgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedl 95 kv+L+G+ GK+S + + + +++ k+ ++l+a+ ++ ++ + +++ +wd Gqe+f +++ + i v D++ e+++ FUN_001208-T1 11 KVVLLGEGCVGKTSlMLRYVQDKFNDKHLTTLQASFLNKRLNID-GQRVNIAIWDTAGQERFHALG-----PIYYRDSNGAILVYDIT---DEDSF 97 89************6679******************99999995.889************997764.....23334444445555666...23444 PP Gtr1_RagA 96 arlketlealsev.speakvfvlihKvDlisedkre 130 ++k+ +++l+++ +++ + + +K+Dl ++++ + FUN_001208-T1 98 FKVKKWVKELKKMlGEDIALCIAGNKIDLEKDRHVD 133 445555555544313455555555666666655555 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 9.7e-07 0.0023 1 100 [. 11 108 .. 11 123 .. 0.65 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 9.7e-07 MMR_HSR1 1 rvaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegk..lelkg..kkielvDtpGliegaseee.gleraflaieeadlillvvd..aeegl 89 +v+++G vGK++L+ + +++ + d++ tT++ + + l+++g +i ++Dt+G e ++ l+ + + +++ ++lv d +e+++ FUN_001208-T1 11 KVVLLGEGCVGKTSLMLRYVQD--KFNDKHLTTLQASFLNkrLNIDGqrVNIAIWDTAG-QE----RFhALGPIYYR--DSNGAILVYDitDEDSF 97 699****************996..7799999**99976541155666346799******.55....33367766664..55666666665422334 PP MMR_HSR1 90 teldeeleell 100 ++++ ++el FUN_001208-T1 98 FKVKKWVKELK 108 44444444432 PP >> LigD_Prim-Pol LigD, primase-polymerase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 1.4e-05 0.033 128 204 .. 131 206 .. 125 210 .. 0.90 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.4e-05 LigD_Prim-Pol 128 lLeelglesfvktSGgkGlhvvvpleekekedevkafakalarelerrapdrvtaemskkkRkgkvfvDylqnargk 204 +++++ ++++kt G+k +h ++l+ k e+ + +++k++ ++ e+ +p+ +e + +Rk+ + vD +q +++k FUN_001208-T1 131 HVDAAEADAYAKTVGAKHFHTSAKLN-KGIEEMFFELTKKMLERQEKSEPRDGLVEKGNGRRKNVLIVDEQQPQQQK 206 56788999******************.55555579***********************************9998877 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.3 8.3e-05 0.19 3 140 .. 11 165 .. 9 168 .. 0.66 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 8.3e-05 PduV-EutP 3 killiGkvgsGKttLtqalkgeelkYkk..tqaiefsdaviDtPGeylenrkl.......ysali.vtaadadvialvqdateeesvfppg..... 83 k++l+G+ +GKt+L+ + + +++ k t + f ++ ++ G+ ++ + ++al ++ d++ lv+d+t+e+s f + FUN_001208-T1 11 KVVLLGEGCVGKTSLMLRYVQDKFNDKHltTLQASFLNKRLNIDGQRVNIAIWdtagqerFHALGpIYYRDSNGAILVYDITDEDSFFKVKkwvke 106 7999999999***99998888777655422667788899999999988876551111111455642556789999999*****9999975311111 PP PduV-EutP 84 fasvfnkeviGiv..tkidlaedeeeieaae..elLklAGakkifkvsavekegieellky 140 + +++ ++ + kidl++ + +++aae + k+ Gak f++sa ++giee++ FUN_001208-T1 107 LKKMLGEDIALCIagNKIDLEK-DRHVDAAEadAYAKTVGAK-HFHTSAKLNKGIEEMFFE 165 44444445443443459***95.5566665511455666765.699***********9755 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.057 1.3e+02 8 29 .. 12 33 .. 6 69 .. 0.82 2 ? 9.4 0.0 0.00075 1.7 38 94 .. 143 201 .. 101 207 .. 0.80 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.057 AAA_22 8 lvltGesGtGKTtllrrlleql 29 +vl Ge +GKT l+ r+++ FUN_001208-T1 12 VVLLGEGCVGKTSLMLRYVQDK 33 58899999*****999998754 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00075 AAA_22 38 lvelpsstspkdllrellralglelek...elskeellaalqealkalaaravliiDEaq 94 +v +++ ++++l + + + + + ++k +++k+e ++ l e +++++ vli+DE q FUN_001208-T1 143 TVGAKHFHTSAKLNKGIEEMFFELTKKmleRQEKSEPRDGLVEKGNGRRK-NVLIVDEQQ 201 5556666677778777777777777778889*******************.*******87 PP >> AAA_14 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.1 0.0013 3.1 5 36 .. 12 43 .. 8 129 .. 0.81 2 ? 1.6 0.0 0.15 3.5e+02 16 71 .. 143 201 .. 141 205 .. 0.59 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0013 AAA_14 5 lvitGpRqvGKTtllkqlikellekesilyln 36 +v++G vGKT l+ ++++++++++++ l+ FUN_001208-T1 12 VVLLGEGCVGKTSLMLRYVQDKFNDKHLTTLQ 43 57778888**************9555544443 PP == domain 2 score: 1.6 bits; conditional E-value: 0.15 AAA_14 16 Ttllkqlikell..ekesilylnlddprlreladeellelllel.lkeekkllflDEiq 71 T+ +k++ + + + + ++++l ++ l+++++ e + l+e+ ++k++l+ DE q FUN_001208-T1 143 TVGAKHFHTSAKlnKGIEEMFFELTKKMLERQEKSEPRDGLVEKgNGRRKNVLIVDEQQ 201 5555555544443333444566666666655555545677777734448899****976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (216 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 842 (0.0329614); expected 510.9 (0.02) Passed bias filter: 626 (0.0245058); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2130.16 // Query: FUN_001209-T1 [L=480] Description: FUN_001209 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-31 109.7 8.9 9e-18 65.1 2.2 2.6 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 4.3e-31 108.8 10.4 1.2e-22 81.1 4.3 2.2 2 Beta-prop_WDR5 WDR5 beta-propeller domain 1.4e-29 103.5 9.2 1.1e-14 54.6 0.7 3.6 4 Beta-prop_THOC3 THOC3 beta-propeller domain 4.1e-29 100.2 15.6 3.2e-08 34.2 0.1 5.5 5 WD40 WD domain, G-beta repeat 2.2e-25 90.0 4.2 6.8e-21 75.3 2.3 2.7 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 5.9e-21 75.2 3.7 2.5e-19 69.9 1.8 2.5 2 WD40_Prp19 Prp19 WD40 domain 2.5e-20 73.3 18.7 2.7e-12 47.0 2.9 3.3 3 WD40_WDHD1_1st WDHD1 first WD40 domain 7.2e-18 65.3 3.4 1.3e-12 48.1 0.6 2.7 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 5.1e-16 59.1 0.2 2.7e-14 53.4 0.1 2.2 2 WDR55 WDR55 1.4e-15 57.9 7.5 4.1e-10 40.0 1.8 4.9 4 Beta-prop_RIG_2nd RIG second beta-propeller 4e-15 56.5 0.5 1.2e-08 35.2 0.1 3.4 3 Beta-prop_EIPR1 EIPR1 beta-propeller 2.6e-14 53.7 0.0 1.8e-13 51.0 0.0 2.3 2 CAF1C_H4-bd Histone-binding protein RBBP4 or s 4.4e-14 53.0 7.5 1.7e-10 41.2 0.5 3.7 4 Beta-prop_EML_2 Echinoderm microtubule-associated 1.5e-12 47.7 4.1 4.5e-06 26.4 0.5 2.7 2 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 1.2e-11 44.7 0.2 2.3e-11 43.8 0.2 1.5 1 WD40_Gbeta G protein beta WD-40 repeat protei 6.6e-11 42.4 7.9 6.2e-06 26.1 1.5 2.6 2 Beta-prop_Aladin Aladin seven-bladed propeller 8.6e-11 42.2 1.4 6e-06 26.4 0.2 3.4 4 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 1.4e-10 41.3 0.6 6.4e-09 35.9 0.2 2.3 3 EIF3I EIF3I 4.9e-09 36.6 0.2 4.9e-09 36.6 0.2 2.4 2 Beta-prop_EML Echinoderm microtubule-associated 2.1e-08 34.2 6.6 3.6e-08 33.4 4.8 2.1 2 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 4.4e-08 33.7 0.5 0.00012 22.7 0.1 4.1 3 ANAPC4_WD40 Anaphase-promoting complex subunit 4.9e-08 32.9 0.4 8.5e-08 32.1 0.4 1.4 1 Beta-prop_WDR19_1st WDR19 first beta-propeller 5.3e-07 30.2 0.6 1e-06 29.3 0.2 1.6 1 eIF2A Eukaryotic translation initiation 6.4e-07 29.4 7.2 0.0012 18.7 0.2 2.8 2 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 6.5e-07 29.5 1.6 7.5e-07 29.3 0.5 1.7 1 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 8.7e-07 28.6 1.1 0.00082 18.8 0.1 3.4 3 Beta-prop_SPT8 SPT8 beta propeller 9.9e-07 28.5 1.0 0.02 14.4 0.3 3.1 3 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 1.2e-06 28.6 0.3 0.0012 18.7 0.1 2.6 3 Beta-prop_HPS5 HPS5 beta-propeller 4.6e-06 26.6 4.4 8.1e-06 25.7 0.4 2.8 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 4.6e-06 26.2 0.1 1.1e-05 25.0 0.1 1.6 1 Beta-prop_SCAP SCAP Beta-propeller 1.2e-05 25.2 2.8 0.0045 16.7 0.1 2.9 3 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 2e-05 24.6 4.2 0.011 15.6 0.0 3.5 4 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 2.9e-05 23.5 3.3 0.097 11.9 0.1 3.4 3 Beta-prop_WDR41 WDR41 5e-05 22.7 5.0 0.00059 19.1 0.5 3.5 4 Beta-prop_IFT140_1st IFT140 first beta-propeller 5.5e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 MIOS_WD40 MIOS, WD40 repeat 9.8e-05 21.9 0.0 0.00022 20.7 0.0 1.6 1 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 0.0001 22.0 2.5 0.001 18.7 1.1 2.7 2 WDR90_beta-prop_4th WDR90, 4th beta-propeller 0.00013 22.4 4.6 0.11 13.0 0.1 4.1 3 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 0.0074 15.7 3.8 0.31 10.3 0.3 3.0 3 NBCH_WD40 Neurobeachin beta propeller domain 0.009 15.1 1.1 0.11 11.5 0.3 2.4 2 Beta-prop_RIG_1st RIG first beta-propeller ------ inclusion threshold ------ 0.016 14.7 0.0 0.53 9.7 0.0 2.4 3 WD_LRWD1 Leucine-rich repeat and WD repeat- 0.077 12.7 1.5 0.18 11.5 0.2 2.2 2 Beta-prop_Vps41 Vps42 beta-propeller 0.08 12.5 0.0 1.5 8.3 0.0 2.4 2 Beta-prop_IFT140_2nd IFT140 second beta-propeller 0.15 11.4 5.2 0.78 9.1 1.1 2.6 2 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 Domain annotation for each model (and alignments): >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.7 0.6 5.7e-18 3.3e-15 32 184 .] 191 373 .. 175 373 .. 0.81 2 ! 65.1 2.2 1.5e-20 9e-18 27 144 .. 296 421 .. 294 426 .. 0.86 Alignments for each domain: == domain 1 score: 56.7 bits; conditional E-value: 5.7e-18 Beta-prop_WDR3_1st 32 vtalaasp..dgkklavGyadgsirlwdlesgel...................evtfngHksavtalafdkd.gsrLasGskDtdiivwDv 100 v+ ++ sp ++ +a+ ++ g++++wd++++ + +tf+gH+ + a+++++ rL++G ++i++w FUN_001209-T1 191 VNRIRNSPipGRHIVATWSEKGKVHIWDISRQVIsvdnpttsagtpmgrdvkpLFTFHGHQVEGFAMDWSNIvPGRLVTGDCKKNIHMWSP 281 667777652256778999999********887765555555555555555554599****999999999986258**************99 PP Beta-prop_WDR3_1st 101 vaeaglf....rLkgHkdqvtsvafle.ekkvlvssSkDtliklWdle...tqhcvktlvghrsevwslalskdekllvtgssdselrvwk 183 +++ + + H+d+v +v++++ e++v +s+S D++i++Wd + ++ c t ++h++ v ++ +++e ++v+g++d +++w+ FUN_001209-T1 282 IEGGSWHvdqrPYNAHTDSVEDVQWSPnEQNVFASCSVDKTIRIWDARaspSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWD 372 987655422225789***********62579***************97333579************************************8 PP Beta-prop_WDR3_1st 184 i 184 + FUN_001209-T1 373 L 373 6 PP == domain 2 score: 65.1 bits; conditional E-value: 1.5e-20 Beta-prop_WDR3_1st 27 geksevtalaaspdg.kklavGyadgsirlwdl...esgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvv...aeaglfrLk 110 ++++v+ ++ sp++ +++a+ + d++ir+wd+ s+++++t ++H + v+++++++++ ++sG+ D i +wD+ +++ + +k FUN_001209-T1 296 AHTDSVEDVQWSPNEqNVFASCSVDKTIRIWDArasPSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRqfqSGVAVAVFK 386 57889*******9862578*************9443457999***********************************862225777889** PP Beta-prop_WDR3_1st 111 gHkdqvtsvaflee.kkvlvssSkDtliklWdlet 144 H+ ++tsv + ++ ++v + s++D+ + lWdl+ FUN_001209-T1 387 HHTAPITSVEWHPSdSSVFAASGSDNQVTLWDLAV 421 ************86267899999*********986 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.5 0.4 9.6e-13 5.6e-10 46 162 .. 186 329 .. 175 331 .. 0.84 2 ! 81.1 4.3 2e-25 1.2e-22 3 120 .. 295 420 .. 293 425 .. 0.68 Alignments for each domain: == domain 1 score: 39.5 bits; conditional E-value: 9.6e-13 Beta-prop_WDR5 46 ghkkGisdvawssd..skllasaSDDktvriwdve...................tgkllktlkgHtnyvfcvaFnp.kgnllvSGsfDetvrlWd 118 h G++ + s+ +++a+ S+ +v+iwd++ k l t++gH+ f+++++ lv+G + +++++W FUN_001209-T1 186 NHIGGVNRIRNSPIpgRHIVATWSEKGKVHIWDISrqvisvdnpttsagtpmgrDVKPLFTFHGHQVEGFAMDWSNiVPGRLVTGDCKKNIHMWS 280 6999*****9998654788999*************99999999998888887666668999*************7515679************** PP Beta-prop_WDR5 119 vrtgkclkt....lpaHsdpvsavdfnrdgt.livsssyDgliriwdte 162 +g ++ +aH+d v v+++ + + +++s+s+D +iriwd++ FUN_001209-T1 281 PIEGGSWHVdqrpYNAHTDSVEDVQWSPNEQnVFASCSVDKTIRIWDAR 329 988876544222389************8765499*************87 PP == domain 2 score: 81.1 bits; conditional E-value: 2e-25 Beta-prop_WDR5 3 kghkkavssvkfspd.gkllasasaDktikiwdv...eegklektleghkkGisdvawssdskllasaSDDktvriwdvetgk...llktlkgHt 90 ++h+ +v v+ sp+ +++as+s Dkti+iwd+ + +++ t ++h + ++ ++w+++ +++s+ DD ++iwd+++ + ++ ++k Ht FUN_001209-T1 295 NAHTDSVEDVQWSPNeQNVFASCSVDKTIRIWDArasPSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQsgvAVAVFKHHT 389 56888888888888734567888888888888873322345777778888888888888888888888888888888877443333778888888 PP Beta-prop_WDR5 91 nyvfcvaFnpk.gnllvSGsfDetvrlWdvr 120 +++v+++p+ +++ ++++ D++v lWd++ FUN_001209-T1 390 APITSVEWHPSdSSVFAASGSDNQVTLWDLA 420 8888888887623444555668888888865 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.035 20 44 79 .. 186 222 .. 170 237 .. 0.78 2 ! 47.7 1.1 2.4e-15 1.4e-12 8 81 .. 257 333 .. 248 345 .. 0.79 3 ! 54.6 0.7 2e-17 1.1e-14 1 83 [. 343 426 .. 343 438 .. 0.88 4 ? -3.0 0.0 6.8 3.9e+03 47 65 .. 449 467 .. 445 472 .. 0.76 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.035 Beta-prop_THOC3 44 ghtdsVeqlawspt.hpdllatassDktvrlWdvrtg 79 h + V++++ sp ++++at s+ +v +Wd+ + FUN_001209-T1 186 NHIGGVNRIRNSPIpGRHIVATWSEKGKVHIWDISRQ 222 488889999999862467889999999******9764 PP == domain 2 score: 47.7 bits; conditional E-value: 2.4e-15 Beta-prop_THOC3 8 vawsa.dGkrLasgsaDktvrvwnleksklsk..etelkghtdsVeqlawspthpdllatassDktvrlWdvrtgks 81 ++ws+ rL++g k + +w++ ++ + + + ++ htdsVe ++wsp++++++a++s Dkt+r+Wd+r++ s FUN_001209-T1 257 MDWSNiVPGRLVTGDCKKNIHMWSPIEGGSWHvdQRPYNAHTDSVEDVQWSPNEQNVFASCSVDKTIRIWDARASPS 333 566431457999************99886644226689***********************************8533 PP == domain 3 score: 54.6 bits; conditional E-value: 2e-17 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklske.telkghtdsVeqlawspthpdllatassDktvrlWdvrtgksta 83 h++ v+ ++w+ + ++sg++D ++++w+l++ ++ + + +k ht +++++w+p+++ ++a+++sD++v lWd+ +k + FUN_001209-T1 343 HDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQSGVAvAVFKHHTAPITSVEWHPSDSSVFAASGSDNQVTLWDLAVEKDDE 426 8899***************************998765542789*********************************99877655 PP == domain 4 score: -3.0 bits; conditional E-value: 6.8 Beta-prop_THOC3 47 dsVeqlawspthpdllata 65 ++V+++ w+ + p +l+++ FUN_001209-T1 449 NDVKEIHWHRQLPGVLIST 467 5788888888888888876 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.11 62 10 39 .] 187 218 .. 181 218 .. 0.79 2 ? 6.2 0.1 0.043 25 2 39 .] 242 280 .. 241 280 .. 0.73 3 ! 34.2 0.1 5.6e-11 3.2e-08 7 39 .] 294 327 .. 289 327 .. 0.90 4 ! 34.2 0.3 5.8e-11 3.3e-08 3 39 .] 336 372 .. 334 372 .. 0.94 5 ! 28.2 0.7 4.6e-09 2.7e-06 4 39 .] 382 418 .. 379 418 .. 0.84 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.11 WD40 10 HtsgVtsla.fspdgsllasg.sdDgtvklWd 39 H +gV+ ++ + g+++++ s+ g+v++Wd FUN_001209-T1 187 HIGGVNRIRnSPIPGRHIVATwSEKGKVHIWD 218 5566777776666677888889*********9 PP == domain 2 score: 6.2 bits; conditional E-value: 0.043 WD40 2 kllrtlkgHtsgVtslafspdgsl...lasgsdDgtvklWd 39 k+l t++gH V + a + ++ l++g+ +++++W+ FUN_001209-T1 242 KPLFTFHGH--QVEGFAMDWSNIVpgrLVTGDCKKNIHMWS 280 7899*****..7866653333333667899*88****9996 PP == domain 3 score: 34.2 bits; conditional E-value: 5.6e-11 WD40 7 lkgHtsgVtslafspdgsll.asgsdDgtvklWd 39 +++Ht++V ++ +sp+ + + as+s D+t+++Wd FUN_001209-T1 294 YNAHTDSVEDVQWSPNEQNVfASCSVDKTIRIWD 327 789****************62699*********9 PP == domain 4 score: 34.2 bits; conditional E-value: 5.8e-11 WD40 3 llrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 + t ++H+++V+ ++++ + ++++sg+dDg +k+Wd FUN_001209-T1 336 CKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWD 372 777889**999*************************9 PP == domain 5 score: 28.2 bits; conditional E-value: 4.6e-09 WD40 4 lrtlkgHtsgVtslafspdgslla..sgsdDgtvklWd 39 ++++k Ht+++ts+ ++p++s ++ sgs D+ v lWd FUN_001209-T1 382 VAVFKHHTAPITSVEWHPSDSSVFaaSGS-DNQVTLWD 418 789*******************6422667.*******9 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.0 8.8e-05 0.051 147 208 .. 202 280 .. 175 289 .. 0.77 2 ! 75.3 2.3 1.2e-23 6.8e-21 87 210 .. 292 420 .. 285 427 .. 0.89 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 8.8e-05 WD40_CDC20-Fz 147 grllAsGgndntvkiwd...................lrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwn 208 ++ +A+ +++++v+iwd r+++pl++++ h+ A++W+ ++ L+tG k+i++w+ FUN_001209-T1 202 RHIVATWSEKGKVHIWDisrqvisvdnpttsagtpmGRDVKPLFTFHGHQVEGFAMDWSNIVPGRLVTGDC--KKNIHMWS 280 56788889999******65555555555555444433455799*************************975..58999997 PP == domain 2 score: 75.3 bits; conditional E-value: 1.2e-23 WD40_CDC20-Fz 87 rtleghssrvgalaw...nenllssGsrdgkilhhDvrtkele.vvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrsls...pllklte 175 r +++h+++v ++w ++n+++s+s d++i+++D r++ ++ ++ t++ah ++v ++w++++ ++ sGg d+++kiwdlr+ + ++ +++ FUN_001209-T1 292 RPYNAHTDSVEDVQWspnEQNVFASCSVDKTIRIWDARASPSKaCKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQsgvAVAVFKH 387 67899**********77446679***************996551566899*********************************9984556889*** PP WD40_CDC20-Fz 176 hkaavkAlaWcpwkkslLatGGGtaDktirlwntn 210 h+a + ++W+p ++s+ a G +D+++ lw+ FUN_001209-T1 388 HTAPITSVEWHPSDSSVFAASG--SDNQVTLWDLA 420 ********************99..59******986 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.04 23 148 167 .. 203 222 .. 198 233 .. 0.84 2 ! 69.9 1.8 4.3e-22 2.5e-19 43 167 .. 292 422 .. 250 435 .. 0.78 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.04 WD40_Prp19 148 lllgtGtkdgtvkiWDiksq 167 ++++t +++g+v+iWDi++q FUN_001209-T1 203 HIVATWSEKGKVHIWDISRQ 222 58899999999999999987 PP == domain 2 score: 69.9 bits; conditional E-value: 4.3e-22 WD40_Prp19 43 atlkghtkkvtavafhpse.dvlvsasaDktvrvwkkeek...etaatlkkhkaevtslsvhptgdylvsaskDgtwalhdletgktllkvkd.ee 133 + +++ht v++v+++p+e +v+ s+s Dkt+r+w++ ++ ++ t+++h+ +v+ +s + + ++vs+++Dg+++++dl++ + + v+ ++ FUN_001209-T1 292 RPYNAHTDSVEDVQWSPNEqNVFASCSVDKTIRIWDARASpskACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQSGVAVAVfKH 387 44789***********976267889**********985433338999***********************************98776666553134 PP WD40_Prp19 134 skeaitsaqfHP.DGlllgtGtkdgtvkiWDiksq 167 ++++its+++HP D +++++ +d++v +WD+ + FUN_001209-T1 388 HTAPITSVEWHPsDSSVFAASGSDNQVTLWDLAVE 422 4679********999****************9755 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 1.8 6.3e-06 0.0037 138 252 .. 200 329 .. 191 335 .. 0.70 2 ! 47.0 2.9 4.7e-15 2.7e-12 177 282 .. 297 406 .. 240 416 .. 0.79 3 ! 35.0 0.5 2.1e-11 1.2e-08 86 160 .. 344 422 .. 332 461 .. 0.78 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 6.3e-06 WD40_WDHD1_1st 138 pkgeylaSsscDGtvkiWdieskec....vktlkvlpksndfsa.......skslcrlawepk.sgkllavPvekevkl...yerdtweeafkls 217 p ++++a+ s G+v+iWdi+ + + +t p+ d+ + ++w+ g+l+ ++k++++ +e ++w ++ + FUN_001209-T1 200 PGRHIVATWSEKGKVHIWDISRQVIsvdnPTTSAGTPMGRDVKPlftfhghQVEGFAMDWSNIvPGRLVTGDCKKNIHMwspIEGGSWHVDQRPY 294 5678999999***********8855211112223445555544333333222234778998541577777779999*973446789***998888 PP WD40_WDHD1_1st 218 knklsedisivafSpcGkyl.aaatvdgeilvWdva 252 + ++ +++ v++Sp+ + + a+++vd++i +Wd+ FUN_001209-T1 295 NAHT-DSVEDVQWSPNEQNVfASCSVDKTIRIWDAR 329 6665.579999*****965439999********975 PP == domain 2 score: 47.0 bits; conditional E-value: 4.7e-15 WD40_WDHD1_1st 177 askslcrlawepksgkllavP.vekevklye.rdtweeafklsknklsedisivafSpcGkylaaatvdgeilvWdvatk...eliervkhekkl 266 +++s+ ++w+p++++++a v+k++++ + r + ++a+kl+++++++d++++++ + ++++++ dg i +Wd+ + +++ +kh++ FUN_001209-T1 297 HTDSVEDVQWSPNEQNVFASCsVDKTIRIWDaRASPSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFqsgVAVAVFKHHT-A 390 3568999************987999****9736678899*************************************87641116677788875.9 PP WD40_WDHD1_1st 267 aitslaWnpkeneLaf 282 +its+ W+p++++++ FUN_001209-T1 391 PITSVEWHPSDSSVFA 406 **********886554 PP == domain 3 score: 35.0 bits; conditional E-value: 2.1e-11 WD40_WDHD1_1st 86 tapvthialskdgkllaagseDftikvvsvedss...kqktleghkapvlsvaldpkg.eylaSsscDGtvkiWdiesk 160 ++v+ i+ ++++ ++++g++D ik+ ++++ + +++++ h+ap++sv+ +p++ + a+s++D +v +Wd+ + FUN_001209-T1 344 DTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQsgvAVAVFKHHTAPITSVEWHPSDsSVFAASGSDNQVTLWDLAVE 422 5678889999999999999999999999885544222677889999999999999987356688888999999998755 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 2.7 1.6e+03 226 246 .. 199 219 .. 183 226 .. 0.67 2 ! 48.1 0.6 2.2e-15 1.3e-12 166 287 .. 242 372 .. 239 375 .. 0.83 3 ! 17.2 0.0 5.6e-06 0.0033 66 119 .. 375 429 .. 372 475 .. 0.79 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.7 Beta-prop_WDR3_2nd 226 vpktHylfsagkdkkvkyWDa 246 +p H + + + +kv WD FUN_001209-T1 199 IPGRHIVATWSEKGKVHIWDI 219 456788888888888888874 PP == domain 2 score: 48.1 bits; conditional E-value: 2.2e-15 Beta-prop_WDR3_2nd 166 kfflslYGhklPvlsldissDs.klivtgsaDknikiwG.ldfGDch...kslfahddsvmsvafvpktHylf.sagkdkkvkyWDadkf. 249 k +++ Gh++ ++d s+ +vtg kni++w ++ G h + +ah+dsv +v++ p+ ++f s++ dk+++ WDa FUN_001209-T1 242 KPLFTFHGHQVEGFAMDWSNIVpGRLVTGDCKKNIHMWSpIEGGSWHvdqRPYNAHTDSVEDVQWSPNEQNVFaSCSVDKTIRIWDARASp 332 6778999***********975415689***********635556555333789**************998777589***********8752 PP Beta-prop_WDR3_2nd 250 ..ekiqtleghagevwalavsskgkfvvsashDksiRlwe 287 + +t ++h +v ++ ++ f+vs++ D +i++w+ FUN_001209-T1 333 skACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWD 372 1134567789*****************************6 PP == domain 3 score: 17.2 bits; conditional E-value: 5.6e-06 Beta-prop_WDR3_2nd 66 dlasaelletieahegavwsvaltp.dekglvtggaDkkvkfwefelveeeeska 119 + +s+ + ++ h++ + sv+ +p d+ + ++g+D++v +w++ + +++e+ + FUN_001209-T1 375 QFQSGVAVAVFKHHTAPITSVEWHPsDSSVFAASGSDNQVTLWDLAVEKDDEKPE 429 568999999***************945566677899**********998875432 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.081 47 107 126 .. 202 221 .. 187 229 .. 0.83 2 ! 53.4 0.1 4.6e-17 2.7e-14 47 172 .. 292 425 .. 266 436 .. 0.80 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.081 WDR55 107 enllatGdddGtvklWDlRk 126 +++at ++G v++WD+ + FUN_001209-T1 202 RHIVATWSEKGKVHIWDISR 221 68999999999999999754 PP == domain 2 score: 53.4 bits; conditional E-value: 4.6e-17 WDR55 47 lslehhkkscraveFsedGkklf.svskDksiavldvetg..klkkkiekahespiysllvi.denllatGdddGtvklWDlRkkk...avmelke 135 ++h++s+ +v++s + +++f s+s Dk+i++ d+ + k k ++ah++ ++ ++ +e ++++G ddG++k+WDlR+ + av +k+ FUN_001209-T1 292 RPYNAHTDSVEDVQWSPNEQNVFaSCSVDKTIRIWDARASpsKACKLTTQAHDTDVNVISWNrNEPFIVSGGDDGVIKIWDLRQFQsgvAVAVFKH 387 55689*************9998857999********987533888899**********98752677999**************8443448999*** PP WDR55 136 hedyisdlvvdeekklLlatsg.dGtltvfnirkkkle 172 h i+++ + ++ ++a+sg d ++t +++ +k + FUN_001209-T1 388 HTAPITSVEWHPSDSSVFAASGsDNQVTLWDLAVEKDD 425 **********9988888888775889999998877655 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0026 1.5 182 249 .. 140 224 .. 130 238 .. 0.70 2 ? 1.3 0.0 0.46 2.6e+02 208 243 .. 245 280 .. 237 289 .. 0.85 3 ! 40.0 1.8 7e-13 4.1e-10 166 276 .. 299 408 .. 295 409 .. 0.85 4 ! 13.6 0.1 7.9e-05 0.046 209 249 .. 384 424 .. 375 431 .. 0.87 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0026 Beta-prop_RIG_2nd 182 Avvandkvivilef..............keeernlet..lkkitasaekasitsvkwsnan.snlllsfsidgkvkvWdleepek 249 A ++++ ++++++ +++++ le+ + + ++ ++ ++ s+ +++ ++s gkv++Wd++ + FUN_001209-T1 140 AALGQQNHVIVMKMseldktfqndqdsdSDDDELLEEepELATAKFNHIGGVNRIRNSPIPgRHIVATWSEKGKVHIWDISRQVI 224 677888999999997777777766665433333333321333333457788999999998769*****************98864 PP == domain 2 score: 1.3 bits; conditional E-value: 0.46 Beta-prop_RIG_2nd 208 itasaekasitsvkwsnansnlllsfsidgkvkvWd 243 +t + ++ + ++ wsn l++ + ++++W+ FUN_001209-T1 245 FTFHGHQVEGFAMDWSNIVPGRLVTGDCKKNIHMWS 280 56667777777899*********************7 PP == domain 3 score: 40.0 bits; conditional E-value: 7e-13 Beta-prop_RIG_2nd 166 ryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepek...eelti 254 ++d++wsp e+n++A ++ dk+i i + + ++ k+t++a+ ++ ++w++ n+ ++s + dg +k+Wdl++ ++ ++ + FUN_001209-T1 299 DSVEDVQWSPNEQNVFASCSVDKTIRIWDARA---SPSKACKLTTQAHDTDVNVISWNR-NEPFIVSGGDDGVIKIWDLRQFQSgvaVAVFK 386 6799*************************984...5566778999************75.678999*************9977543257788 PP Beta-prop_RIG_2nd 255 tykcpmlcglFlPtdenivlcg 276 +++p+++ + P+d ++ ++ FUN_001209-T1 387 HHTAPITSVEWHPSDSSVFAAS 408 8999***********9886555 PP == domain 4 score: 13.6 bits; conditional E-value: 7.9e-05 Beta-prop_RIG_2nd 209 tasaekasitsvkwsnansnlllsfsidgkvkvWdleepek 249 + +++ a itsv+w +++s ++ +++ d++v +Wdl+ ++ FUN_001209-T1 384 VFKHHTAPITSVEWHPSDSSVFAASGSDNQVTLWDLAVEKD 424 567899*****************************987765 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.26 1.5e+02 63 235 .. 185 220 .. 173 233 .. 0.55 2 ! 19.7 0.0 1.2e-06 0.00067 202 280 .] 248 326 .. 239 326 .. 0.89 3 ! 35.2 0.1 2.1e-11 1.2e-08 182 280 .] 323 417 .. 322 417 .. 0.89 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.26 Beta-prop_EIPR1 63 wsheeeilglwssPslskksllavssseeaaifqisenvsseleriasldkkasqvLWdleGlqnevksiseealilvsldeskkgkevskysl 156 ++h + + sP ++++ FUN_001209-T1 185 FNHIGGVNRIRNSPIPGRHIVA------------------------------------------------------------------------ 206 4444444444555555555444........................................................................ PP Beta-prop_EIPR1 157 ggeelrvaAldphdsslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiR 235 t + g v+i+Di FUN_001209-T1 207 -----------------------------------------------------------------TWSEKGKVHIWDIS 220 .................................................................55555555555553 PP == domain 2 score: 19.7 bits; conditional E-value: 1.2e-06 Beta-prop_EIPR1 202 hgfgk.vravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 hg + a+d+++ +++l+t + ++++ +g s + ++ +ah+ v+ v++ p+ +++ scs d+t+++w FUN_001209-T1 248 HGHQVeGFAMDWSNIVPGRLVTGDCKKNIHMWSPI-EGGSWHVDQRPYNAHTDSVEDVQWSPNEQNVFASCSVDKTIRIW 326 5555414689**********************965.8999999999********************************99 PP == domain 3 score: 35.2 bits; conditional E-value: 2.1e-11 Beta-prop_EIPR1 182 lqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssds 275 + ++D Ra +k +t++++ v+ + +++ ++ +++ gddgv++i+D+R ++ + + ++k h+ +++v++ p + +++sd+ FUN_001209-T1 323 IRIWDARASPSKA-CKLTTQAHDTDVNVISWNRNEP-FIVSGGDDGVIKIWDLR--QFQSGVAVAVFKHHTAPITSVEWHPSDSSVFAASGSDN 412 789****998888.555555569999*****99876.689**************..4478888999**************************** PP Beta-prop_EIPR1 276 tlkLw 280 ++ Lw FUN_001209-T1 413 QVTLW 417 ***** PP >> CAF1C_H4-bd Histone-binding protein RBBP4 or subunit C of CAF1 complex # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.0 0.0 3.2e-16 1.8e-13 3 68 .. 91 156 .. 89 157 .. 0.91 2 ? -0.9 0.0 5 2.9e+03 23 35 .. 389 401 .. 385 416 .. 0.72 Alignments for each domain: == domain 1 score: 51.0 bits; conditional E-value: 3.2e-16 CAF1C_H4-bd 3 yliwkknapllYdllhthalewPsLsvqwlpdt..eeaknltkqrlll.GTqtsgeeqnyllvakvslp 68 +l+++++a Y+++h+ +++ P+Ls++++pd+ ++ ++ +++ GTq+ ++qn+++v+k+s + FUN_001209-T1 91 ELTFDRSA---YEMYHAAQTNAPCLSFDVIPDSlgDSRTKFPMTAYIVaGTQAALGQQNHVIVMKMSEL 156 7899****...*********************7676777888899*********************976 PP == domain 2 score: -0.9 bits; conditional E-value: 5 CAF1C_H4-bd 23 ewPsLsvqwlpdt 35 + P sv+w p++ FUN_001209-T1 389 TAPITSVEWHPSD 401 57999****9973 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.29 1.7e+02 8 30 .. 200 222 .. 197 235 .. 0.83 2 ! 11.8 0.1 0.00027 0.16 228 265 .. 290 327 .. 265 328 .. 0.85 3 ! 8.9 0.0 0.0022 1.3 9 30 .. 310 331 .. 308 342 .. 0.77 4 ! 41.2 0.5 3e-13 1.7e-10 187 265 .. 340 418 .. 330 419 .. 0.95 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.29 Beta-prop_EML_2 8 psepqfvTagdDktvrlWdlekk 30 p +++++T ++ + v +Wd++++ FUN_001209-T1 200 PGRHIVATWSEKGKVHIWDISRQ 222 788999*************9765 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00027 Beta-prop_EML_2 228 kykkykgHsshVtnvrFladdsylistGGaDasvfqWk 265 +++ y++H+ V +v++++++++++ D+++ W FUN_001209-T1 290 DQRPYNAHTDSVEDVQWSPNEQNVFASCSVDKTIRIWD 327 678899**************************999995 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0022 Beta-prop_EML_2 9 sepqfvTagdDktvrlWdlekk 30 ++++f++++ Dkt+r+Wd+++ FUN_001209-T1 310 EQNVFASCSVDKTIRIWDARAS 331 5689**************9754 PP == domain 4 score: 41.2 bits; conditional E-value: 3e-13 Beta-prop_EML_2 187 klsdgtdinavdrsksekllatgddfGkvklfkyPctkkkakykkykgHsshVtnvrFladdsylistGGaDasvfqWk 265 +++ td+n+++ +++e ++++g d G +k++ ++++ ++ ++k H++ +t+v++ ++ds ++ + G D+ v W FUN_001209-T1 340 TQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQSGVAVAVFKHHTAPITSVEWHPSDSSVFAASGSDNQVTLWD 418 56788*************************************************************************7 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.2 2.3e-07 0.00013 66 203 .. 184 330 .. 167 336 .. 0.78 2 ! 26.4 0.5 7.7e-09 4.5e-06 127 205 .. 341 423 .. 334 440 .. 0.83 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 2.3e-07 Beta-prop_CAF1B_HIR1 66 ltrhqkavnvvrfsps..gelLasgdDesviiiWklkeeeeeinlle.eeeeenketwlvlkvlrGhledvyDlswspd.skklisgsv 150 h vn +r sp +++a+ ++ +++ iW +++ ++++ + + + l +++Gh + + + ws+ +l++g FUN_001209-T1 184 KFNHIGGVNRIRNSPIpgRHIVATWSEKGKVHIWDISRQVISVDNPTtSAGTPMGRDVKPLFTFHGHQVEGFAMDWSNIvPGRLVTGDC 272 5568889999999975326799999*********9999987554433245555556666777999***********9862579****** PP Beta-prop_CAF1B_HIR1 151 DntailWdvekgkklai....lkdhkgfvqgvawdPknqyv.atlssDrslrifdikt 203 ++ +W +g + ++ + h + v v w P++q v a+ s D+++ri+d+++ FUN_001209-T1 273 KKNIHMWSPIEGGSWHVdqrpYNAHTDSVEDVQWSPNEQNVfASCSVDKTIRIWDARA 330 *******988887777643446789999********98755278899******99865 PP == domain 2 score: 26.4 bits; conditional E-value: 7.7e-09 Beta-prop_CAF1B_HIR1 127 rGhledvyDlswspdskklisgsvDntailWdvek...gkklailkdhkgfvqgvawdPknqyvatls.sDrslrifdiktkk 205 + h dv +sw +++ +++sg D + +Wd+++ g +a++k+h + +v w P+++ v ++s sD ++ ++d++ +k FUN_001209-T1 341 QAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQfqsGVAVAVFKHHTAPITSVEWHPSDSSVFAASgSDNQVTLWDLAVEK 423 67999***************************876222667999****************98775554399999999887665 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.8 0.2 4e-14 2.3e-11 158 298 .. 268 418 .. 240 427 .. 0.81 Alignments for each domain: == domain 1 score: 43.8 bits; conditional E-value: 4e-14 WD40_Gbeta 158 vtssgdttcalwd.ietgqqtt...vfvghtgdvmslslapd.trlfvsgacdasaklwdvreg...lcrqtfighesdinaiaffpngealatgs 245 vt +w ie g ++ + ht v + +p+ +++f s ++d ++++wd r + c+ t h++d+n i++ n +++g FUN_001209-T1 268 VTGDCKKNIHMWSpIEGGSWHVdqrPYNAHTDSVEDVQWSPNeQNVFASCSVDKTIRIWDARASpskACKLTTQAHDTDVNVISWNRNEPFIVSGG 363 55555556667754777765441116899***********972689****************864448**************************** PP WD40_Gbeta 246 ddatcrlfdlradqellvy.shdniicgitsvafsksgrlllag.yddfncnvwd 298 dd +++dlr q ++ + + itsv + s ++a d ++ +wd FUN_001209-T1 364 DDGVIKIWDLRQFQSGVAVaVFKHHTAPITSVEWHPSDSSVFAAsGSDNQVTLWD 418 ***********99976543145566789******999887776515677889998 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 1.5 1.1e-08 6.2e-06 109 186 .. 297 377 .. 247 380 .. 0.76 2 ! 20.0 0.4 7.6e-07 0.00044 102 144 .. 382 423 .. 375 433 .. 0.84 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 1.1e-08 Beta-prop_Aladin 109 ghspvtsvaWspkGdlLvsaspvdtsilvWdvake..tavpL.rrvggggvsllkwspdgskllaatpssvfrvwetetWt 186 + +v +v+Wsp+ + + +++ vd++i +Wd ++ +a L +++ + v +++w+ ++ ++++ v ++w+ ++++ FUN_001209-T1 297 HTDSVEDVQWSPNEQNVFASCSVDKTIRIWDARASpsKACKLtTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQ 377 345899*********9999999*********8754224444515677899**************************99876 PP == domain 2 score: 20.0 bits; conditional E-value: 7.6e-07 Beta-prop_Aladin 102 aqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdvaket 144 + v+k ++ +p+tsv+W+p+ + + +as d+++ +Wd a e+ FUN_001209-T1 382 VAVFK-HHTAPITSVEWHPSDSSVFAASGSDNQVTLWDLAVEK 423 34444.4579****************************99876 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.038 22 204 225 .. 201 222 .. 176 235 .. 0.84 2 ! 7.2 0.1 0.0074 4.3 206 263 .. 265 326 .. 242 329 .. 0.80 3 ! 22.2 0.1 1.9e-07 0.00011 192 263 .. 298 371 .. 289 374 .. 0.91 4 ! 26.4 0.2 1e-08 6e-06 192 263 .. 344 417 .. 334 419 .. 0.79 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.038 Beta-prop_WDR36-Utp21_1st 204 gepvlatgsssGdialwdLekr 225 g+++ at s++G++ +wd++++ FUN_001209-T1 201 GRHIVATWSEKGKVHIWDISRQ 222 67899999**********9876 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0074 Beta-prop_WDR36-Utp21_1st 206 pvlatgsssGdialwdLekr...rlvhvlrnaHeggvtkleflpg.qpllvtsgaDNslkew 263 l+tg + +i +w ++ ++ + naH+ +v +++ p+ q+++ + + D ++++w FUN_001209-T1 265 GRLVTGDCKKNIHMWSPIEGgswHVDQRPYNAHTDSVEDVQWSPNeQNVFASCSVDKTIRIW 326 5588888888999998666547777788889***********98747899999*******99 PP == domain 3 score: 22.2 bits; conditional E-value: 1.9e-07 Beta-prop_WDR36-Utp21_1st 192 egpvtsisFrtDgepvlatgsssGdialwdLekr..rlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkew 263 +++v + ++++v+a+ s + +i +wd + + + +++aH++ v+ +++ ++p++v+ g D +k+w FUN_001209-T1 298 TDSVEDVQWSPNEQNVFASCSVDKTIRIWDARASpsKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIW 371 45777888888899*****************9988899***********************************9 PP == domain 4 score: 26.4 bits; conditional E-value: 1e-08 Beta-prop_WDR36-Utp21_1st 192 egpvtsisFrtDgepvlatgsssGdialwdLekr..rlvhvlrnaHeggvtkleflpg.qpllvtsgaDNslkew 263 ++ v+ is +ep++++g ++G i +wdL + ++ + + H++++t++e+ p+ ++ sg+DN++ w FUN_001209-T1 344 DTDVNVISWNR-NEPFIVSGGDDGVIKIWDLRQFqsGVAVAVFKHHTAPITSVEWHPSdSSVFAASGSDNQVTLW 417 46777777766.489*****************9644566666788999********9835688999******999 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2.8 1.7e+03 284 292 .. 187 195 .. 129 230 .. 0.55 2 ! 11.9 0.0 0.00021 0.12 138 218 .. 243 329 .. 210 335 .. 0.74 3 ! 35.9 0.2 1.1e-11 6.4e-09 45 217 .. 244 419 .. 239 427 .. 0.78 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2.8 EIF3I 284 HFGPintla 292 H G +n + FUN_001209-T1 187 HIGGVNRIR 195 333333333 PP == domain 2 score: 11.9 bits; conditional E-value: 0.00021 EIF3I 138 pvlkieveeskvtvalwsal.dktiitghedgeiskydlktgeklks....vkehekqitdlqlskd.ktylitaskDktaklldve 218 p+++++ ++ + ++ ws+ ++tg + +i+ ++ +g + ++h+++++d+q+s++ ++++ ++s Dkt +++d++ FUN_001209-T1 243 PLFTFHGHQVEGFAMDWSNIvPGRLVTGDCKKNIHMWSPIEGGSWHVdqrpYNAHTDSVEDVQWSPNeQNVFASCSVDKTIRIWDAR 329 55566666666667778765156789999999999999766554332012257799********9761678889999****999986 PP == domain 3 score: 35.9 bits; conditional E-value: 1.1e-11 EIF3I 45 lGtyeGheGavwsidvds.ettllvtgsadntvklWdvetGkelkt....le.tktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeee 134 l t++Gh+ +++d ++ +lvtg +++++W+ +G + + ++ ++ +v v++s+++++++++ + + +i++ d r + FUN_001209-T1 244 LFTFHGHQVEGFAMDWSNiVPGRLVTGDCKKNIHMWSPIEGGSWHVdqrpYNaHTDSVEDVQWSPNEQNVFASCS----VDKTIRIWDARASP--- 332 569************86615689*************977776544311222213457889999999999887654....56678888877654... PP EIF3I 135 eeepvlkieveeskvtvalwsaldktiitghedgeiskydlkt...geklksvkehekqitdlqls.kdktylitaskDktaklldv 217 ++ l+++ +++ v+v+ w+ ++ +i++g +dg i+ +dl++ g +++ k+h++ it ++++ +d++++ ++ D++ +l+d+ FUN_001209-T1 333 SKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQfqsGVAVAVFKHHTAPITSVEWHpSDSSVFAASGSDNQVTLWDL 419 566778889999****************************9872214467778999********98357788888889***999996 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.8 4.7e+02 168 183 .. 265 280 .. 245 289 .. 0.85 2 ! 36.6 0.2 8.4e-12 4.9e-09 2 144 .. 291 425 .. 290 450 .. 0.79 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.8 Beta-prop_EML 168 gdvitGdsnGnilvWs 183 g ++tGd + ni++Ws FUN_001209-T1 265 GRLVTGDCKKNIHMWS 280 899************8 PP == domain 2 score: 36.6 bits; conditional E-value: 8.4e-12 Beta-prop_EML 2 QRhYlgHtddikclavhpnkl.lvatGqvagsskdekeakphiriWdsetl.etlavlgkgefergvsclaFskadggklLaavdesnehvlsvWd 95 QR Y Htd ++ ++ pn++ + a+ v +iriWd++ + l+++ ++ v ++ +++ ++v ++ v+ +Wd FUN_001209-T1 291 QRPYNAHTDSVEDVQWSPNEQnVFASCSVD----------KTIRIWDARASpSKACKLTTQAHDTDVNVISWNRNE----PFIVSGGDDGVIKIWD 372 9*****************976155665553..........47*****987614445577899**********9866....4778888889****** PP Beta-prop_EML 96 ...wqkgeklaetktskdkvlavefhpldknllvtcGk.khiaFWtlegkkle 144 +q+g +a k ++ ++ +ve+hp+d++++ G ++++ W l +k + FUN_001209-T1 373 lrqFQSGVAVAVFKHHTAPITSVEWHPSDSSVFAASGSdNQVTLWDLAVEKDD 425 54455667888999**********************96378999*99755543 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 4 2.3e+03 152 166 .. 207 221 .. 192 225 .. 0.68 2 ! 33.4 4.8 6.1e-11 3.6e-08 11 167 .. 266 422 .. 255 427 .. 0.73 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 4 Beta-prop_TEP1_2nd 152 scssdGsvglWdiek 166 + s+ G v +Wdi++ FUN_001209-T1 207 TWSEKGKVHIWDISR 221 445666666666654 PP == domain 2 score: 33.4 bits; conditional E-value: 6.1e-11 Beta-prop_TEP1_2nd 11 vlvsGaedgslqvWkleesss..qcllllkahqkavlglals...qkllasasedltvrlWskelltqpekaeslsslsvlrghtgavtcc 96 lv+G ++++W+ e+ s + ++ah +v + s q+++as+s d t+r+W + p+k +++ + + h++ v+ FUN_001209-T1 266 RLVTGDCKKNIHMWSPIEGGSwhVDQRPYNAHTDSVEDVQWSpneQNVFASCSVDKTIRIWDARAS--PSK----ACKLTTQAHDTDVNVI 350 688888888888888766654113455677888888887766444778999999999999987654..545....4455567799999999 PP Beta-prop_TEP1_2nd 97 sfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWt..kddllvscssdGsvglWdieke 167 s++ + + +gg d + +Wd+r+ ++ v + + h +t+ W +++++ ++ sd v+lWd+ e FUN_001209-T1 351 SWNRNEPFIVSGGDDGVIKIWDLRQFQSGVAVAVF-KHHTAPITSVEWHpsDSSVFAASGSDNQVTLWDLAVE 422 99999999999999999999999998888766555.5689999999996224556667778999999998765 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.0 0.018 11 33 68 .. 293 329 .. 286 334 .. 0.76 2 ! 22.7 0.1 2e-07 0.00012 18 89 .. 324 398 .. 319 400 .. 0.86 3 ? 6.8 0.0 0.019 11 36 67 .. 387 419 .. 382 426 .. 0.83 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.018 ANAPC4_WD40 33 seekedsevtslaWkpdGk.lLavaysdgevrlldve 68 + ++++ +v++++W+p+++ ++a d ++r+ d+ FUN_001209-T1 293 PYNAHTDSVEDVQWSPNEQnVFASCSVDKTIRIWDAR 329 45678899*********9725555556889**99986 PP == domain 2 score: 22.7 bits; conditional E-value: 2e-07 ANAPC4_WD40 18 evllkRlnwqrvwklseekedsevtslaWkpdGklLavaysdgevrlldv...esgklvhslsaksdkitcleWa 89 +++ R + + kl+++++d v+ ++W+ ++ +++ + +dg +++ d +sg v ++ ++ it++eW FUN_001209-T1 324 RIWDARASPSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLrqfQSGVAVAVFKHHTAPITSVEWH 398 566678888888888*******************************9986222689999999999999******6 PP == domain 3 score: 6.8 bits; conditional E-value: 0.019 ANAPC4_WD40 36 kedsevtslaWkpdG.klLavaysdgevrlldv 67 ++++ +ts++W+p+ ++a + sd++v l d FUN_001209-T1 387 HHTAPITSVEWHPSDsSVFAASGSDNQVTLWDL 419 57789*******9652799**********9986 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.1 0.4 1.5e-10 8.5e-08 39 152 .. 299 420 .. 257 455 .. 0.84 Alignments for each domain: == domain 1 score: 32.1 bits; conditional E-value: 1.5e-10 Beta-prop_WDR19_1st 39 gkctaleWdkdgdlLaiiqeksslvllwdant..kktskldtglkdk.ltfllWskkspiLavGtskGnlllYnkktsk...kipilGkH 122 ++ ++W+ +++ + + ++ +++ +wda+ +k+ kl t++ d+ +++++W +++p+++ G + G + +++ ++ + + + H FUN_001209-T1 299 DSVEDVQWSPNEQNVFASCSVDKTIRIWDARAspSKACKLTTQAHDTdVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQsgvAVAVFKHH 388 568899******99999999*********988335778999999886599************************8876622258889999 PP Beta-prop_WDR19_1st 123 skkItcgaws..kenlLalgseDktltisnae 152 + It+ +w+ ++ ++a +++D+++t+ + FUN_001209-T1 389 TAPITSVEWHpsDSSVFAASGSDNQVTLWDLA 420 *********7436789***********99864 PP >> eIF2A Eukaryotic translation initiation factor eIF2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.2 1.7e-09 1e-06 60 176 .. 299 417 .. 288 422 .. 0.81 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 1.7e-09 eIF2A 60 gpihdvaWspnskefavvyGkmpakvslfdlk......vkvilkleeqkrNtiffspkgklvllaGfgnlaGeieiwdvkkkkk...iakaeaana 146 + dv+Wspn+++ +++++ ++d + +k++++ + + N i ++ ++ +++ +G G i+iwd ++++ +a +++ +a FUN_001209-T1 299 DSVEDVQWSPNEQNVF-ASCSVDKTIRIWDARaspskaCKLTTQAHDTDVNVISWNRNEPFIVSGGD---DGVIKIWDLRQFQSgvaVAVFKHHTA 390 4699*******98854.45689*********878888899999999******************995...577*****997664333555555554 PP eIF2A 147 ..tlvewspdgryvlTattaprlrvdngfkiw 176 t+vew+p+++ v a+ + dn +++w FUN_001209-T1 391 piTSVEWHPSDSSVFAASGS-----DNQVTLW 417 3499********99999877.....6666666 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.2 4e-05 0.023 234 270 .. 292 329 .. 288 333 .. 0.85 2 ! 18.7 0.2 2e-06 0.0012 153 228 .. 340 420 .. 328 424 .. 0.73 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 4e-05 Beta-prop_WDR36-Utp21_2nd 234 RkfsghknritDltfspdarWl.itasmDstirtwdlp 270 R ++ h+ +++D+ +sp+ + + + s+D tir+wd FUN_001209-T1 292 RPYNAHTDSVEDVQWSPNEQNVfASCSVDKTIRIWDAR 329 77899************9887615679*********76 PP == domain 2 score: 18.7 bits; conditional E-value: 2e-06 Beta-prop_WDR36-Utp21_2nd 153 ekahkkavrGvavdalnqvvitagadkklkfwkfkskklletlk....leasisklvlhr.essllavalddfsilvvDid 228 ++ah++ v+ ++ + + ++++g d+ +k+w++++ + ++ +a+i+++ h +ss+ a + d ++++ D+ FUN_001209-T1 340 TQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQSGVAVAvfkhHTAPITSVEWHPsDSSVFAASGSDNQVTLWDLA 420 678999999999999999999999999999998888765443321112567788888885378888888888888888875 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.5 1.3e-09 7.5e-07 60 163 .. 296 402 .. 289 424 .. 0.81 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 1.3e-09 WD40_RFWD3 60 lHskaiRdlaFnseqdslllsaslDktlkltsllsn....tvvqtYetdspvWsCcWseddsnylyaGlqnGsvlvfDiRqtssevselekeesrs 151 H++++ d++++++++++ s+s+Dkt+++ + + t d++v W+ +++ ++ +G +G + ++D+Rq +s v +++++ FUN_001209-T1 296 AHTDSVEDVQWSPNEQNVFASCSVDKTIRIWDARASpskaCKLTTQAHDTDVNVISWNRNEP-FIVSGGDDGVIKIWDLRQFQSGVAVAVFKHHTA 390 59****************************99864311113445555566677778*98777.566899*************************** PP WD40_RFWD3 152 pvvsLayvpaaa 163 p+ s++ p+++ FUN_001209-T1 391 PITSVEWHPSDS 402 ****98766544 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.1 0.18 1.1e+02 217 286 .. 155 224 .. 131 238 .. 0.63 2 ? 5.7 0.0 0.014 8.1 262 293 .. 309 340 .. 290 345 .. 0.84 3 ! 18.8 0.1 1.4e-06 0.00082 140 203 .. 342 408 .. 333 437 .. 0.67 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.18 Beta-prop_SPT8 217 eldsllgdddededsdadekekekknse.neaknadeiskeslnvvydesvfltsGlnGsiniwdkrnska 286 eld +++d+ d dsd de +e+ + + +++ + + + + + + t +G ++iwd ++ FUN_001209-T1 155 ELDKTFQNDQ-DSDSDDDELLEEEPELAtAKFNHIGGVNRIRNSPIPGRHIVATWSEKGKVHIWDISRQVI 224 5666666655.333444444444444441355555555555555788888888888999999999655444 PP == domain 2 score: 5.7 bits; conditional E-value: 0.014 Beta-prop_SPT8 262 ydesvfltsGlnGsiniwdkrnskapvlkler 293 +++vf + ++ +i+iwd r s + + kl+ FUN_001209-T1 309 NEQNVFASCSVDKTIRIWDARASPSKACKLTT 340 4799*****************99999988875 PP == domain 3 score: 18.8 bits; conditional E-value: 1.4e-06 Beta-prop_SPT8 140 khsnvvnilrlnstedkflsgswdkkilewdln...tgkvineykgatselsalelrplfstvtles 203 h vn++ n +e ++sg+ d i wdl+ g+ + +k +t+ ++++e p +s+v s FUN_001209-T1 342 AHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRqfqSGVAVAVFKHHTAPITSVEWHPSDSSVFAAS 408 5777788888888888888888888888888754445677778888888888888888777765444 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.69 4e+02 54 119 .. 154 221 .. 138 228 .. 0.71 2 ! 14.4 0.3 3.4e-05 0.02 18 56 .. 309 347 .. 287 356 .. 0.71 3 ! 12.2 0.0 0.00015 0.087 126 207 .. 340 419 .. 333 434 .. 0.67 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.69 WD40_MABP1-WDR62_2nd 54 nellkvlyvdeelsalkdvelaasekkdeseldsknGvRvlkvsp.dgkhl.asGDrsGniriydlet 119 +el k+ d++ ++ d+ l+++ + ++++++ Gv ++ sp g+h+ a+ +G+++i+d++ FUN_001209-T1 154 SELDKTFQNDQDSDSDDDELLEEEPELATAKFNHIGGVNRIRNSPiPGRHIvATWSEKGKVHIWDISR 221 56666666666666655554555556667788999999999999755777537788999999999864 PP == domain 2 score: 14.4 bits; conditional E-value: 3.4e-05 WD40_MABP1-WDR62_2nd 18 lpagsFltcssDdtiRlWnleeksseetalkrniysnel 56 ++ F +cs D+tiR+W + ++ s++++l+ + + +++ FUN_001209-T1 309 NEQNVFASCSVDKTIRIWDARASPSKACKLTTQAHDTDV 347 45678***************9998888777766666655 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00015 WD40_MABP1-WDR62_2nd 126 ieahdsevlcleyskpetglkllasasRDRlihvfdvekdys..llqtlddhsssitavkfaeeeeklkliscgaDksilfrka 207 +ahd++v + + ++ +++s++ D +i+++d+++ s + ++ h + it+v + +++++ ++g+D +++ + FUN_001209-T1 340 TQAHDTDVNVISWNRN---EPFIVSGGDDGVIKIWDLRQFQSgvAVAVFKHHTAPITSVEWHPSDSSVF-AASGSDNQVTLWDL 419 5788888877776654...46888888888888888876443224556778888888888887776664.45566666655444 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 4 2.3e+03 65 89 .. 194 220 .. 185 230 .. 0.72 2 ! 18.7 0.1 2e-06 0.0012 60 142 .. 299 379 .. 291 385 .. 0.85 3 ! 7.7 0.0 0.0044 2.6 52 98 .. 382 430 .. 377 465 .. 0.87 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 4 Beta-prop_HPS5 65 vaisp..dedlvavatsrglvvvveln 89 + sp ++va +++g+v+++++ FUN_001209-T1 194 IRNSPipGRHIVATWSEKGKVHIWDIS 220 555554456778888899999999875 PP == domain 2 score: 18.7 bits; conditional E-value: 2e-06 Beta-prop_HPS5 60 gaistvaisp.dedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsvtklssskas 142 ++ v sp +++++a + + + +++ +++k +++ +++ v+ + W+++ + +G + G++++ +l + ++ FUN_001209-T1 299 DSVEDVQWSPnEQNVFASCSVDKTIRIWDAR---ASPSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQSG 379 5789999***78899**************95...77777777777777889**************************9988654 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0044 Beta-prop_HPS5 52 lqlltakegaistvaisp.dedlvavatsrglvvvvelnier.kqkpkr 98 + ++ ++ ++i+ v p d ++a ++s+ +v++++l +e+ +kp++ FUN_001209-T1 382 VAVFKHHTAPITSVEWHPsDSSVFAASGSDNQVTLWDLAVEKdDEKPEE 430 678999************9999****************99763677765 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 1 6e+02 6 24 .. 202 220 .. 199 237 .. 0.84 2 ? 6.5 0.1 0.01 6 256 291 .] 289 327 .. 232 327 .. 0.72 3 ! 25.7 0.4 1.4e-08 8.1e-06 7 109 .. 312 421 .. 307 425 .. 0.77 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1 Beta-prop_WDR90_POC16_2nd 6 rrqlatvseDetiriWdld 24 r+ +at se ++iWd++ FUN_001209-T1 202 RHIVATWSEKGKVHIWDIS 220 5668999*********986 PP == domain 2 score: 6.5 bits; conditional E-value: 0.01 Beta-prop_WDR90_POC16_2nd 256 infqvfiGhsekvqqvaftpdqqevl...svGdaiflWd 291 ++ + + h+++v+ v+++p++q+v sv +i +Wd FUN_001209-T1 289 VDQRPYNAHTDSVEDVQWSPNEQNVFascSVDKTIRIWD 327 555667788888888888888888853336777888887 PP == domain 3 score: 25.7 bits; conditional E-value: 1.4e-08 Beta-prop_WDR90_POC16_2nd 7 rqlatvseDetiriWdldtl.qqlydfsas..eeaPcavafhPskqvfacGfssGvvrvfsvea...tsllaehkqhrgkvtgl 84 + +a s D+tiriWd + + ++++ + ++++ +++ +++G ++Gv++++++++ +a +k+h + +t++ FUN_001209-T1 312 NVFASCSVDKTIRIWDARASpSKACKLTTQahDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQfqsGVAVAVFKHHTAPITSV 395 567999**********975425556665441155567899********************99752114568899********** PP Beta-prop_WDR90_POC16_2nd 85 vfspdgeylysa.cslGslalydase 109 p+++ +++a +s +++l+d + FUN_001209-T1 396 EWHPSDSSVFAAsGSDNQVTLWDLAV 421 ****9999987526778888888765 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 0.1 1.9e-08 1.1e-05 322 415 .. 317 420 .. 309 424 .. 0.81 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 1.9e-08 Beta-prop_SCAP 322 Gsqdhtvrvyrleds...cclftlqGhsGgitavyidqt.mvlasGGqdGaiclwdv...ltGsrvshvyghrGdvtslvct...tscvissGld 406 s d t+r++ s c +t q h + + ++ + sGG dG i +wd+ +G v+ h +ts+ + +s+ +sG d FUN_001209-T1 317 CSVDKTIRIWDARASpskACKLTTQAHDTDVNVISWNRNePFIVSGGDDGVIKIWDLrqfQSGVAVAVFKHHTAPITSVEWHpsdSSVFAASGSD 411 689******976655334799************98876516889************833347999998889999*****985222566789**** PP Beta-prop_SCAP 407 dlisiwdrs 415 + +++wd + FUN_001209-T1 412 NQVTLWDLA 420 *******65 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.5 0.0057 3.3 64 130 .. 244 313 .. 202 323 .. 0.79 2 ! 16.7 0.1 7.8e-06 0.0045 11 47 .. 341 377 .. 333 419 .. 0.79 3 ? -0.3 0.0 1.1 6.5e+02 17 46 .. 392 422 .. 381 474 .. 0.49 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0057 Beta-prop_WDR35_TULP_N 64 nqtlegHsgavqvvaW.NekykkLtssDenGliivWm.lykgswv.eeminnrnksvvkdlkWssdgqki 130 t +gH+ + ++ W N +L + D + i +W ++ gsw+ ++ n + v+d++Ws+++q++ FUN_001209-T1 244 LFTFHGHQVEGFAMDWsNIVPGRLVTGDCKKNIHMWSpIEGGSWHvDQRPYNAHTDSVEDVQWSPNEQNV 313 557889999999999*555678**************835668997255677889999********99987 PP == domain 2 score: 16.7 bits; conditional E-value: 7.8e-06 Beta-prop_WDR35_TULP_N 11 ipnnvklksvaWnkeqgyiavggedglLkvLklesek 47 ++++ +++++Wn+++ +i gg+dg++k+ +l + + FUN_001209-T1 341 QAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQ 377 4667889999999999999999999999998887644 PP == domain 3 score: -0.3 bits; conditional E-value: 1.1 Beta-prop_WDR35_TULP_N 17 lksvaWnkeq.gyiavggedglLkvLklese 46 ++sv W+ ++ + a++g+d + + +l e FUN_001209-T1 392 ITSVEWHPSDsSVFAASGSDNQVTLWDLAVE 422 3444443322022333333333333333333 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 8 4.6e+03 195 210 .. 202 217 .. 195 222 .. 0.79 2 ! 15.6 0.0 1.8e-05 0.011 32 64 .. 295 327 .. 288 331 .. 0.92 3 ? 2.1 0.0 0.24 1.4e+02 31 65 .. 340 373 .. 330 384 .. 0.62 4 ! 6.8 0.2 0.0089 5.2 27 65 .. 381 419 .. 358 423 .. 0.83 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 8 Beta-prop_WDR75_1st 195 ddciatGhedGkirlw 210 +at e Gk+ +w FUN_001209-T1 202 RHIVATWSEKGKVHIW 217 5678999999999999 PP == domain 2 score: 15.6 bits; conditional E-value: 1.8e-05 Beta-prop_WDR75_1st 32 kghtdlvtGvalnpsnhlqvyscsldgtvrlwd 64 ++htd v v+ p+++ scs+d t+r+wd FUN_001209-T1 295 NAHTDSVEDVQWSPNEQNVFASCSVDKTIRIWD 327 79************9999999***********9 PP == domain 3 score: 2.1 bits; conditional E-value: 0.24 Beta-prop_WDR75_1st 31 lkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 ++h v + n +n+ + s dg +++wd FUN_001209-T1 340 TQAHDTDVNVISWN-RNEPFIVSGGDDGVIKIWDL 373 45565555555554.34455566666777777764 PP == domain 4 score: 6.8 bits; conditional E-value: 0.0089 Beta-prop_WDR75_1st 27 cvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 +v ++k ht +t v+ +ps+ ++ d v lwd FUN_001209-T1 381 AVAVFKHHTAPITSVEWHPSDSSVFAASGSDNQVTLWDL 419 6888999*************9877777779*******97 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.043 25 319 357 .. 185 226 .. 175 237 .. 0.70 2 ? 5.6 0.1 0.014 7.9 319 353 .. 295 331 .. 289 340 .. 0.80 3 ! 11.9 0.1 0.00017 0.097 317 355 .. 339 378 .. 334 392 .. 0.83 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.043 Beta-prop_WDR41 319 kahdsnvlhiak..lpnrqlvsc.sedgsvriwelrekkkss 357 h v i + +p r++v+ se g v iw+++ ++ s FUN_001209-T1 185 FNHIGGVNRIRNspIPGRHIVATwSEKGKVHIWDISRQVISV 226 55656666665433789999975499*********9886554 PP == domain 2 score: 5.6 bits; conditional E-value: 0.014 Beta-prop_WDR41 319 kahdsnvlhiaklpnrqlv..scsedgsvriwelrek 353 +ah v + pn q v scs d ++riw+ r FUN_001209-T1 295 NAHTDSVEDVQWSPNEQNVfaSCSVDKTIRIWDARAS 331 5888889999999998865559**********98865 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00017 Beta-prop_WDR41 317 qkkahdsnvlhiaklpnr.qlvscsedgsvriwelrekkk 355 +ahd++v i+ +n +vs +dg ++iw+lr+ + FUN_001209-T1 339 TTQAHDTDVNVISWNRNEpFIVSGGDDGVIKIWDLRQFQS 378 568*********9888763689*************98654 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 1.2 6.8e+02 336 355 .. 203 222 .. 179 233 .. 0.69 2 ? -0.3 0.1 0.78 4.6e+02 101 130 .. 250 280 .. 239 298 .. 0.77 3 ! 19.1 0.5 1e-06 0.00059 62 132 .. 300 374 .. 286 390 .. 0.78 4 ? 2.4 0.1 0.12 70 60 88 .. 389 418 .. 377 437 .. 0.58 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1.2 Beta-prop_IFT140_1st 336 giLaaGtnkGrvalwkkvae 355 +i+a+ +kG+v +w + + FUN_001209-T1 203 HIVATWSEKGKVHIWDISRQ 222 34455555555555544443 PP == domain 2 score: -0.3 bits; conditional E-value: 0.78 Beta-prop_IFT140_1st 101 hkaeitvlewssn.gsrLvsgdksGvlvvWk 130 h+ e ++ws+ rLv+gd + + +W FUN_001209-T1 250 HQVEGFAMDWSNIvPGRLVTGDCKKNIHMWS 280 4444457899986268***********9996 PP == domain 3 score: 19.1 bits; conditional E-value: 1e-06 Beta-prop_IFT140_1st 62 qvtvlsWHPtkk.ilavgwesGevlvlneq...dkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWkld 132 +v ++W P+++ + a + + + ++ + +k ++ ++++h+++++v++w+ n +vsg Gv+ +W l FUN_001209-T1 300 SVEDVQWSPNEQnVFASCSVDKTIRIWDARaspSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLR 374 677799999866155666667889999865111677777899******************************875 PP == domain 4 score: 2.4 bits; conditional E-value: 0.12 Beta-prop_IFT140_1st 60 svqvtvlsWHPtkk.ilavgwesGevlvln 88 + t+++WHP+ + + a + + +v+++ FUN_001209-T1 389 TAPITSVEWHPSDSsVFAASGSDNQVTLWD 418 344566666666541334444445555554 PP >> MIOS_WD40 MIOS, WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 1.9e-07 0.00011 143 257 .. 298 419 .. 289 434 .. 0.77 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 1.9e-07 MIOS_WD40 143 ndaclslcwlprdqkllla.gmhrnlaifdlrntsqkmfvntkavqgvtvdpyfhdrvasfy.....egqvaiwdlrkfekpv..ltlteqpkplt 230 d++ + w p +q+++ + + + + i+d r + k t + v+ +r f +g + iwdlr+f+ v + + p+t FUN_001209-T1 298 TDSVEDVQWSPNEQNVFAScSVDKTIRIWDARASPSKACKLTTQAHDTDVNVISWNRNEPFIvsggdDGVIKIWDLRQFQSGVavAVFKHHTAPIT 393 57777889******99865268999*******99888877666666666666666665544322222899*********98761145678899*** PP MIOS_WD40 231 kvawcptrtgllatltrdsniirlydm 257 v w p+ + ++a+ d+ + l+d+ FUN_001209-T1 394 SVEWHPSDSSVFAASGSDN-QVTLWDL 419 ************9988875.4567776 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 3.8e-07 0.00022 189 303 .. 305 420 .. 287 424 .. 0.79 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 3.8e-07 Beta-prop_DCAF4 189 qfalqapllfnGcrsGeifai.dlrqrsrkgkgwkatrlfhdsavtsvqllqeeqlllaadmaGkiklwdlratkc...vkqyeGhvneyaylp 278 q++ + +f c + i d r +k++k t+ hd+ v + ++e ++++ G ik+wdlr+ ++ v ++ h+ + + FUN_001209-T1 305 QWSPNEQNVFASCSVDKTIRIwDARASP--SKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIWDLRQFQSgvaVAVFKHHTAPITSVE 396 5555566667777766655553666555..899999999*********************************9884433899999999999999 PP Beta-prop_DCAF4 279 lhvneeeGllvavGqdcytriwslk 303 h + + + +a G d +w l FUN_001209-T1 397 WHPS-DSSVFAASGSDNQVTLWDLA 420 9976.5679999**********985 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 1 6e+02 11 30 .. 202 221 .. 191 228 .. 0.76 2 ! 18.7 1.1 1.8e-06 0.001 57 154 .. 308 411 .. 300 426 .. 0.73 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1 WDR90_beta-prop_4th 11 eshlatcsedGsvrvwslas 30 +at se G v +w ++ FUN_001209-T1 202 RHIVATWSEKGKVHIWDISR 221 45579999********8865 PP == domain 2 score: 18.7 bits; conditional E-value: 1.8e-06 WDR90_beta-prop_4th 57 aeqqqvvaGys.dGtlrvfsis...rtemelklhphavaltaiaysadGqtilsgdkdGlvav...ssprtGvtlrvlsdhkGapitviq 139 +++q+v a s d t+r++ + + +l h + + i++ + i+sg+ dG++ + + ++Gv++ v++ h+ apit+++ FUN_001209-T1 308 PNEQNVFASCSvDKTIRIWDARaspSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIKIwdlRQFQSGVAVAVFK-HHTAPITSVE 396 55666666554499****9764112567899999**************************9982224566899999987.5679***999 PP WDR90_beta-prop_4th 140 stskeyedfGvegae 154 + + + f + g++ FUN_001209-T1 397 WHPSDSSVFAASGSD 411 887666666555544 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 5.5 3.2e+03 14 30 .. 204 220 .. 193 224 .. 0.79 2 ? 7.3 0.1 0.011 6.4 12 30 .. 311 329 .. 297 336 .. 0.71 3 ! 13.0 0.1 0.00018 0.11 12 58 .. 356 406 .. 343 417 .. 0.72 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 5.5 Beta-prop_TEP1_C 14 liisAseDrtvKlWdre 30 ++ + se +v +Wd + FUN_001209-T1 204 IVATWSEKGKVHIWDIS 220 4557799999****974 PP == domain 2 score: 7.3 bits; conditional E-value: 0.011 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdre 30 +++ s s D+t+++Wd + FUN_001209-T1 311 QNVFASCSVDKTIRIWDAR 329 5678899**********76 PP == domain 3 score: 13.0 bits; conditional E-value: 0.00018 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkk...qvGlFvC.eapvlvlevnpnpesele 58 + i+s D +K+Wd ++ + v++F +ap++++e p+ +s FUN_001209-T1 356 EPFIVSGGDDGVIKIWDLRQFQsgvAVAVFKHhTAPITSVEWHPSDSSVFA 406 568**************877653336999975269******9877665544 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 2 1.2e+03 137 158 .. 203 224 .. 199 235 .. 0.81 2 ! 10.3 0.3 0.00054 0.31 121 193 .. 295 369 .. 282 376 .. 0.71 3 ? 5.2 0.0 0.02 12 112 163 .. 377 429 .. 371 478 .. 0.81 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2 NBCH_WD40 137 svlatGsydttvmvwevlrars 158 ++at s v +w+++r+ + FUN_001209-T1 203 HIVATWSEKGKVHIWDISRQVI 224 6899999999999999998754 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00054 NBCH_WD40 121 rqhkdvvscvavts.dgsvlatGsydttvmvwevlrarssekrvrntqtelsrkdvvia...ekplhilcGhddiit 193 + h d v v+ + + +v a+ s d t+ +w++ + k + t++ ++ +vi+ ++p+ + G d +i FUN_001209-T1 295 NAHTDSVEDVQWSPnEQNVFASCSVDKTIRIWDARAS--PSKACKLTTQAHDTDVNVISwnrNEPFIVSGGDDGVIK 369 56899999998876157899*************8744..44444444444444446664333678877777777775 PP == domain 3 score: 5.2 bits; conditional E-value: 0.02 NBCH_WD40 112 sdGrlvqsirqhkdvvscvav.tsdgsvlatGsydttvmvwevlrarssekrv 163 + G v ++h +++v sd sv a+ d v +w++ + ek FUN_001209-T1 377 QSGVAVAVFKHHTAPITSVEWhPSDSSVFAASGSDNQVTLWDLAVEKDDEKPE 429 6788888899999988888752699*****************99887777654 PP >> Beta-prop_RIG_1st RIG first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.3 0.0002 0.11 408 473 .. 298 365 .. 288 378 .. 0.80 2 ! 9.1 0.1 0.001 0.6 414 485 .. 350 424 .. 331 434 .. 0.73 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.0002 Beta-prop_RIG_1st 408 tlsktsve.sarpdilLvSidaeevimiwnantgahcgknyskskatgklknvlWlnds.tivslsrn 473 t s ++v+ s +++ + +S + +++i iw+a+ + + + + + + ++ ++W ++ +ivs + + FUN_001209-T1 298 TDSVEDVQwSPNEQNVFASCSVDKTIRIWDARASPSKACKLTTQAHDTDVNVISWNRNEpFIVSGGDD 365 556666663588999*******************9999999999999999999**877758**98765 PP == domain 2 score: 9.1 bits; conditional E-value: 0.001 Beta-prop_RIG_1st 414 vesarpdilLvSidaeevimiwnantgahcgknyskskatgklknvlWlnds...tivslsrnqLffwsleydsk 485 ++ r+++ +vS ++ vi iw+ ++ ++ ++ t+ +++v W ++ + s s nq+++w l++++ FUN_001209-T1 350 ISWNRNEPFIVSGGDDGVIKIWDLRQFQSGVAVAVFKHHTAPITSVEWHPSDssvFAASGSDNQVTLWDLAVEKD 424 33478899***************9998877666666667777889***86552323668899*******999875 PP >> WD_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, WD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 8.5 4.9e+03 303 325 .. 199 221 .. 194 231 .. 0.74 2 ? 2.1 0.0 0.19 1.1e+02 130 164 .. 295 329 .. 291 353 .. 0.81 3 ? 9.7 0.0 0.00092 0.53 112 171 .. 365 427 .. 350 435 .. 0.78 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 8.5 WD_LRWD1 303 cpdknlvlcgdeegsvwiydveh 325 p + +v e+g v i+d+ + FUN_001209-T1 199 IPGRHIVATWSEKGKVHIWDISR 221 67777888888888888888764 PP == domain 2 score: 2.1 bits; conditional E-value: 0.19 WD_LRWD1 130 rahkkaiatlcfspthethlftasydkriilwdig 164 ah ++ + +sp + + ++s dk i +wd FUN_001209-T1 295 NAHTDSVEDVQWSPNEQNVFASCSVDKTIRIWDAR 329 58999999999***999988899*********974 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00092 WD_LRWD1 112 rgmvrll...hvragfccsvirahkkaiatlcfspthethlftasydkriilwdigvpnhdyk 171 g++++ + ++g++++v + h i+++ + p+ + + ++ d+++ lwd+ v + d k FUN_001209-T1 365 DGVIKIWdlrQFQSGVAVAVFKHHTAPITSVEWHPSDSSVFAASGSDNQVTLWDLAVEKDDEK 427 555555400045689********************987766666689**********999977 PP >> Beta-prop_Vps41 Vps42 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.2 0.00031 0.18 51 170 .. 294 419 .. 288 424 .. 0.73 2 ? -1.7 0.0 3.2 1.9e+03 260 291 .. 422 455 .. 411 458 .. 0.80 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00031 Beta-prop_Vps41 51 fkahrasisslsid.tdGeylAsaSmDGtvvigslseeeeiavdFkrpvkavaldpnysksssksfisGgkagkv.ilsernwLgkrkdtvLde 142 ++ah+ s+++++ + ++ +++As+S+D t+ i + ++a++ + + ++ ++++ ++sGg+ g + i r + v+++ FUN_001209-T1 294 YNAHTDSVEDVQWSpNEQNVFASCSVDKTIRIWDARASPSKACKLTTQAHDTDVNVISWNRNEPFIVSGGDDGVIkIWDLRQFQSGVAVAVFKH 387 567777777777652456799***********99999999999988888888887777666778899999989872444556666666778888 PP Beta-prop_Vps41 143 gegpiveikwv..ddliaWm..ndkgvkiydi 170 pi++++w+ d+ ++ + +d+ v++ d+ FUN_001209-T1 388 HTAPITSVEWHpsDSSVFAAsgSDNQVTLWDL 419 89999999996446666665234677777666 PP == domain 2 score: -1.7 bits; conditional E-value: 3.2 Beta-prop_Vps41 260 vk..eisekterklakrpelkiinslsetleeis 291 +k e+ e+t rkl +p+l i++ +++++ei+ FUN_001209-T1 422 EKddEKPEETGRKLDVPPQLLFIHMGQNDVKEIH 455 443366788999999**********999999986 PP >> Beta-prop_IFT140_2nd IFT140 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.42 2.4e+02 124 137 .. 209 222 .. 201 229 .. 0.81 2 ? 8.3 0.0 0.0026 1.5 104 135 .. 343 374 .. 335 377 .. 0.81 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.42 Beta-prop_IFT140_2nd 124 tdngvikifDlsrR 137 +++g ++i+D+sr+ FUN_001209-T1 209 SEKGKVHIWDISRQ 222 689999*****996 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0026 Beta-prop_IFT140_2nd 104 seaEGepvlldvngsfLvvgtdngvikifDls 135 +++ + ++ + n+ f+v g d gviki+Dl FUN_001209-T1 343 HDTDVNVISWNRNEPFIVSGGDDGVIKIWDLR 374 566667777888999***************95 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.075 43 109 140 .. 295 328 .. 290 338 .. 0.83 2 ? 9.1 1.1 0.0013 0.78 108 176 .. 340 410 .. 332 432 .. 0.76 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.075 Beta-prop_DCAF12 109 kghkdwifaiawl..sdtvavsGsrdgtlalwrv 140 ++h+d + ++w +++v s s+d t+ +w FUN_001209-T1 295 NAHTDSVEDVQWSpnEQNVFASCSVDKTIRIWDA 328 589*********7324688999**********75 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0013 Beta-prop_DCAF12 108 rkghkdwifaiawl.sdtvavsGsrdgtlalwrvdpdklnasialkneaelpvya.hirPkeleaiPkass 176 ++h + i w ++ +vsG dg + +w + + ++ ++a ++++ p+ + + +P++ ++ ++ s FUN_001209-T1 340 TQAHDTDVNVISWNrNEPFIVSGGDDGVIKIWDLRQFQSGVAVAVFKHHTAPITSvEWHPSDSSVFAASGS 410 578999999999973567999***********999999999999999999988763567777666655443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (480 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 903 (0.0353494); expected 510.9 (0.02) Passed bias filter: 605 (0.0236837); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 44 (0.00172245); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 44 [number of targets reported over threshold] # CPU time: 0.44u 0.43s 00:00:00.87 Elapsed: 00:00:00.44 # Mc/sec: 4404.72 // Query: FUN_001210-T1 [L=230] Description: FUN_001210 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-07 31.5 0.0 0.0036 17.6 0.0 2.7 3 RRM_1 RNA recognition motif 0.0039 17.5 0.0 2.7 8.4 0.0 2.3 2 RRM_occluded Occluded RNA-recognition motif ------ inclusion threshold ------ 0.052 14.2 0.0 0.24 12.0 0.0 2.1 1 RRM_10 RRM domain Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 4.2e-07 0.0036 1 42 [. 23 67 .. 23 68 .. 0.94 2 ! 10.9 0.0 5.2e-05 0.45 41 68 .. 76 103 .. 69 104 .. 0.90 3 ? -2.7 0.0 0.92 7.8e+03 9 23 .. 214 228 .. 212 229 .. 0.79 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 4.2e-07 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd...etgrskgfa 42 ++++ Lp++++ +++++Fs +G++ ++ l r+ +t++ k+++ FUN_001210-T1 23 VYLSRLPQSMNPTKIRRIFSMYGEVGRLFLQREgdaATKKRKKYG 67 799**************************9999889999999987 PP == domain 2 score: 10.9 bits; conditional E-value: 5.2e-05 RRM_1 41 fafVeFedeedaekAlealngkelggre 68 + +eF+d++ a++ +ln++++gg++ FUN_001210-T1 76 EGWIEFKDKRIAKAVAMSLNNTTIGGKR 103 5789*********************985 PP == domain 3 score: -2.7 bits; conditional E-value: 0.92 RRM_1 9 dvteeeLkelFskfG 23 +++++ L+++F G FUN_001210-T1 214 SISRDLLRKVFTATG 228 688999999998765 PP >> RRM_occluded Occluded RNA-recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0012 10 4 41 .. 23 59 .. 21 67 .. 0.88 2 ! 8.4 0.0 0.00031 2.7 43 66 .. 79 102 .. 77 104 .. 0.93 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0012 RRM_occluded 4 isllnlsDtvndariralveekegeikkivlvpdheGA 41 + l l+ +n ++ir++++ + ge+ +++l+ + +A FUN_001210-T1 23 VYLSRLPQSMNPTKIRRIFSMY-GEVGRLFLQREGDAA 59 6678899***************.******999877666 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00031 RRM_occluded 43 vefkdekdagkasLaLdgsefegk 66 +efkd+++a ++++L+++++ gk FUN_001210-T1 79 IEFKDKRIAKAVAMSLNNTTIGGK 102 9********************987 PP >> RRM_10 RRM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 2.9e-05 0.24 35 81 .. 59 105 .. 14 115 .. 0.76 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.9e-05 RRM_10 35 kapkkvkifpkksersssGlvefesveeAleaLvlaNhtpienpsgk 81 ++ k+ k + ++r + G +ef++++ A ++ + +N+t+i ++ + FUN_001210-T1 59 ATKKRKKYGGSGRKRFTEGWIEFKDKRIAKAVAMSLNNTTIGGKRRE 105 3333333344447999************************9876654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (230 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 917 (0.0358974); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 2353.04 // Query: FUN_001211-T1 [L=439] Description: FUN_001211 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-19 69.8 0.0 4.8e-19 69.4 0.0 1.1 1 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family ------ inclusion threshold ------ 0.047 13.7 0.1 1.5 8.8 0.1 2.3 2 Exo_endo_phos2 Endonuclease/Exonuclease/phosphatase family 2 Domain annotation for each model (and alignments): >> Exo_endo_phos Endonuclease/Exonuclease/phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.4 0.0 3.8e-23 4.8e-19 1 224 [] 31 292 .. 31 292 .. 0.87 Alignments for each domain: == domain 1 score: 69.4 bits; conditional E-value: 3.8e-23 xxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Exo_endo_phos 1 ltwNvngg....nadaardparldalaellraydpDvllLQEvdlddaealllalla..lggyysyvysggggggggGvailsrfpltsvivrtls 90 lt N++g + ++ r+ +ae l++ + D++ LQE++ + + + + l+ + +y+ g g+Gv++lsr+p+ + ++ +s FUN_001211-T1 31 LTLNCWGIpyvsK----MWEERKILIAEELAKGHYDIVSLQEIWSRRDFEMISEMVHdvLP-HTHYF---YSGVIGSGVCVLSRYPIIDAFTYRYS 118 699*****55554....47777999*********************988888888764433.33333...4589********************** PP xxxxxxxxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Exo_endo_phos 91 edgdpslrialapvggtlvvlvvl................pappapprlarreqrlllllllaallaarsgpvilaGDfNaapdsgdlrrllsrgl 170 ++g+ + + ++gg+ v++ + + ++ + +r + +l ++++ l ++++ v+++GD+N p++ +r +++ ++ FUN_001211-T1 119 LNGYMYNITHGDWFGGKAVGYCLIdhpkqpihffathmhaEYSESHQYVSHRVVQSYQLSQFIQHLTRPTDVVLVCGDMNCKPSELCYRIIKDVTG 214 ************************************************************************************************ PP xx...............xx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...................xxxxx RF Exo_endo_phos 171 ll...............sf...ggggtgfgttptartpnggsrlDyilvsgglavrsvgvlidpgal...................tgSDH 224 l+ ++ + +++++ +p p g r+Dyi+++ ++++ +SDH FUN_001211-T1 215 LAdawekhglieggcygNTadvSHNTFSGDKSPVKGGPRDGNRIDYIFYR-------------CDGDafkcvkcevtmrhvpgkqfSFSDH 292 ***9999999888777622567899************************9.............2222555556666666667777777776 PP >> Exo_endo_phos2 Endonuclease/Exonuclease/phosphatase family 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.1 0.00012 1.5 115 180 .. 135 200 .. 32 222 .. 0.78 2 ? 2.7 0.0 0.0083 1.1e+02 250 287 .. 257 297 .. 244 298 .. 0.70 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00012 Exo_endo_phos2 115 KGavairltlkdtslcfinvHlaageen....veeRnadlkkiaeslslkdgksikdheivfllGDlNyR 180 K+ + ++ ++ + f++ H++a+ ++ v++R + + ++ ++ + +++v++ GD+N FUN_001211-T1 135 KAVGYCLIDHPKQPIHFFATHMHAEYSEshqyVSHRVVQSYQLSQFIQH----LTRPTDVVLVCGDMNCK 200 554455555666679*********9988444555555554444444433....348899*********86 PP == domain 2 score: 2.7 bits; conditional E-value: 0.0083 Exo_endo_phos2 250 wtDriLykssskadlslkllkYe......sraeiklSDHrPVsa 287 + D+i+y+ + +a + +k+ e ++ ++SDH++Vsa FUN_001211-T1 257 RIDYIFYRCDGDAFKCVKC---EvtmrhvPGKQFSFSDHEGVSA 297 5788999888743333333...2222323778999*******98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (439 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 892 (0.0349188); expected 510.9 (0.02) Passed bias filter: 636 (0.0248972); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4356.43 // Query: FUN_001212-T1 [L=76] Description: FUN_001212 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-11 43.8 0.2 4.1e-11 43.2 0.2 1.4 1 G-gamma GGL domain ------ inclusion threshold ------ 0.058 14.0 0.3 0.061 13.9 0.3 1.1 1 ADIP Afadin- and alpha -actinin-Binding 0.09 13.4 0.5 0.12 13.0 0.5 1.4 1 Cys_rich_FGFR Cysteine rich repeat 0.21 12.5 0.7 0.28 12.0 0.7 1.2 1 Styelin Styelin Domain annotation for each model (and alignments): >> G-gamma GGL domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.2 0.2 6.4e-15 4.1e-11 7 69 .] 17 76 .] 5 76 .] 0.92 Alignments for each domain: == domain 1 score: 43.2 bits; conditional E-value: 6.4e-15 G-gamma 7 lkreieqLkeelkrerikvSkAaeelikYceqrsekDpllpgvwgppakeNPwrekkgcCwil 69 l+ ++eqL++e+ r k+S ++e+l ++c++++ Dpll + p +NP+r+ + +C+ l FUN_001212-T1 17 LRIQVEQLRREAFLSRKKISACSEDLARFCQEKRSDDPLLGKI---PNANNPYRDRGMSCLLL 76 55678**************************************...89********9999875 PP >> ADIP Afadin- and alpha -actinin-Binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.3 9.5e-06 0.061 67 109 .. 6 48 .. 3 63 .. 0.89 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 9.5e-06 ADIP 67 eierlqseierlkeqledlerelalleakerqlekklktleqk 109 +++ ++e++ l q+e+l+re+ l+ +k + +l++ +q FUN_001212-T1 6 ALSQRENEFQNLRIQVEQLRREAFLSRKKISACSEDLARFCQE 48 56788*************************9999999887775 PP >> Cys_rich_FGFR Cysteine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.5 1.9e-05 0.12 12 41 .. 22 51 .. 14 75 .. 0.70 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.9e-05 Cys_rich_FGFR 12 eeeaeDykldpeLykaCksdiekfCseiee 41 e+ + l+++ +aC +d+ +fC+e+ + FUN_001212-T1 22 EQLRREAFLSRKKISACSEDLARFCQEKRS 51 555556667777789**********99632 PP >> Styelin Styelin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.7 4.4e-05 0.28 37 59 .] 11 33 .. 3 33 .. 0.91 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 4.4e-05 Styelin 37 DeefqefmkeveqareeeLlsrq 59 ++efq+ +veq r e +lsr+ FUN_001212-T1 11 ENEFQNLRIQVEQLRREAFLSRK 33 57*******************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (76 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1023 (0.040047); expected 510.9 (0.02) Passed bias filter: 763 (0.0298689); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.35s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 778.67 // Query: FUN_001213-T1 [L=547] Description: FUN_001213 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-95 313.0 6.8 7.3e-26 90.5 0.2 4.1 4 Annexin Annexin ------ inclusion threshold ------ 0.017 15.6 0.2 26 5.4 0.0 3.2 3 DUF7516 Domain of unknown function (DUF7516) 0.053 14.1 0.3 51 4.6 0.0 4.1 4 Stonustoxin_helical Stonustoxin helical domain Domain annotation for each model (and alignments): >> Annexin Annexin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.5 0.2 8.5e-30 7.3e-26 2 66 .] 248 312 .. 247 312 .. 0.98 2 ! 80.0 0.1 1.7e-26 1.4e-22 1 65 [. 319 383 .. 319 384 .. 0.98 3 ! 58.8 0.0 6.8e-20 5.8e-16 2 61 .. 403 463 .. 402 468 .. 0.95 4 ! 85.2 0.2 3.8e-28 3.3e-24 1 65 [. 478 542 .. 478 543 .. 0.99 Alignments for each domain: == domain 1 score: 90.5 bits; conditional E-value: 8.5e-30 Annexin 2 dAelLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfeklllaL 66 d+elL+kam+g+Gtde++li+I+++Rsnaq+ +ir+ Yk+++gkdL +d+kse+sG++e++llaL FUN_001213-T1 248 DCELLRKAMRGAGTDEQALIDIVVKRSNAQRVEIRKRYKTMFGKDLMNDLKSELSGNLEDCLLAL 312 899************************************************************98 PP == domain 2 score: 80.0 bits; conditional E-value: 1.7e-26 Annexin 1 ydAelLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfekllla 65 +dA+ L++am+g+Gtde+ li+Il+tR+n ++ +i++aY + y +dLekd setsG+f++ll++ FUN_001213-T1 319 FDAKCLRRAMRGAGTDEESLIDILCTRTNSEIAEIKKAYTEYYRRDLEKDCVSETSGHFKRLLVS 383 69*************************************************************97 PP == domain 3 score: 58.8 bits; conditional E-value: 6.8e-20 Annexin 2 dAe.lLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfek 61 A+ l ++++k++Gtde+ ++ +la+Rs +ql++++++Y + +++d+ ++i++e+sGd++ FUN_001213-T1 403 EAQdLFQAGEKKWGTDESRFNVVLASRSFPQLRATFDEYVRVSQRDILNSIDREMSGDVRA 463 589899****************************************************986 PP == domain 4 score: 85.2 bits; conditional E-value: 3.8e-28 Annexin 1 ydAelLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfekllla 65 y+A++L k+mkg+Gtd+ tli+I+++Rs+++l +i+ a+ +ky k+L+k+i++++sGd++kllla FUN_001213-T1 478 YFADRLWKSMKGAGTDDATLIRIVVSRSEIDLVEIKTAFLQKYHKTLYKMIQGDCSGDYKKLLLA 542 89*************************************************************98 PP >> DUF7516 Domain of unknown function (DUF7516) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.042 3.6e+02 25 40 .. 280 295 .. 268 302 .. 0.86 2 ? 4.2 0.0 0.0077 66 24 45 .. 351 372 .. 338 387 .. 0.85 3 ? 5.4 0.0 0.0031 26 17 40 .. 503 526 .. 497 530 .. 0.88 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.042 DUF7516 25 evqkaYkekygveLnk 40 e++k+Yk ++g+ L + FUN_001213-T1 280 EIRKRYKTMFGKDLMN 295 89*********99965 PP == domain 2 score: 4.2 bits; conditional E-value: 0.0077 DUF7516 24 qevqkaYkekygveLnkkelkr 45 e++kaY e y++ L k+++++ FUN_001213-T1 351 AEIKKAYTEYYRRDLEKDCVSE 372 689**************99876 PP == domain 3 score: 5.4 bits; conditional E-value: 0.0031 DUF7516 17 eekeVkyqevqkaYkekygveLnk 40 +++e+++ e+++a+ +ky++ L k FUN_001213-T1 503 SRSEIDLVEIKTAFLQKYHKTLYK 526 5789****************9976 PP >> Stonustoxin_helical Stonustoxin helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.029 2.4e+02 56 75 .. 255 274 .. 249 280 .. 0.87 2 ? 4.6 0.0 0.006 51 56 77 .. 327 348 .. 279 354 .. 0.91 3 ? 0.8 0.0 0.091 7.7e+02 42 76 .. 369 403 .. 350 414 .. 0.76 4 ? -2.1 0.0 0.72 6.1e+03 50 76 .. 480 506 .. 461 519 .. 0.73 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.029 Stonustoxin_helical 56 airggkeeeeelvdlLkske 75 a+rg + +e++l+d++ +++ FUN_001213-T1 255 AMRGAGTDEQALIDIVVKRS 274 78*************98876 PP == domain 2 score: 4.6 bits; conditional E-value: 0.006 Stonustoxin_helical 56 airggkeeeeelvdlLkskees 77 a+rg + +ee+l+d+L ++ +s FUN_001213-T1 327 AMRGAGTDEESLIDILCTRTNS 348 689*************999887 PP == domain 3 score: 0.8 bits; conditional E-value: 0.091 Stonustoxin_helical 42 ykltfqkelaelLpairggkeeeeelvdlLkskee 76 + ++ + ++lL ++ +g+++e++ vd+ k ++e FUN_001213-T1 369 CVSETSGHFKRLLVSMCQGNRDESTTVDMEKARKE 403 55555667889999***********9998776654 PP == domain 4 score: -2.1 bits; conditional E-value: 0.72 Stonustoxin_helical 50 laelLpairggkeeeeelvdlLkskee 76 +l +++g + ++++l++++ s++e FUN_001213-T1 480 ADRLWKSMKGAGTDDATLIRIVVSRSE 506 455567889999999999999887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (547 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 629 (0.0246232); expected 510.9 (0.02) Passed bias filter: 492 (0.0192601); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 5480.53 // Query: FUN_001214-T1 [L=313] Description: FUN_001214 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-45 155.5 0.7 4.2e-45 155.1 0.7 1.2 1 Metallophos Calcineurin-like phosphoesterase ------ inclusion threshold ------ 0.015 16.2 0.3 0.031 15.3 0.3 1.5 1 STPPase_N Serine-threonine protein phosphatase N-terminal 0.17 12.9 0.7 0.41 11.6 0.7 1.6 1 zf-TAZ TAZ zinc finger Domain annotation for each model (and alignments): >> Metallophos Calcineurin-like phosphoesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 155.1 0.7 5e-49 4.2e-45 2 193 .. 55 248 .. 54 249 .. 0.95 Alignments for each domain: == domain 1 score: 155.1 bits; conditional E-value: 5e-49 Metallophos 2 rilvigDlHgegqfddllellekl.rpeekpdlvliaGDlvdrg..sletevlellallvky.ipvflvrGNHd.........fydeclrkygeln 84 +++v+gD+H gqf+dl+el++ r++++++l++ GD+vdrg s+et v +l+ l+v++ +++ ++rGNH+ fydeclrkyg+ FUN_001214-T1 55 PVTVCGDVH--GQFHDLMELFKIGgRSPDTNYLFM--GDYVDRGyySVET-VTLLVTLKVRFpHRITILRGNHEsrqitqvygFYDECLRKYGN-- 143 799******..**********99997778******..*******666666.66669999999*******************************9.. PP Metallophos 85 llarpwkafvevfnllplaaliggkillvhGgls.elvtlddirgldrprevpeeg...dlllsdarkkadwvivlgHaplyrgasylfgpealrk 176 a++wk+f++ f++lpl al++++i+++hGgls ++ tld ir ldr +evp+eg dll+sd ++ g++ ++rga+y+fg++ + FUN_001214-T1 144 --ANVWKYFTDLFDYLPLTALVDSQIFCLHGGLSpSIDTLDHIRALDRIQEVPHEGpmcDLLWSD------PDDRGGWGISPRGAGYTFGQDISET 231 ..99*************************************************************......999********************** PP Metallophos 177 llkrngvdlvlsGHtHv 193 + ng++l+ ++H+ v FUN_001214-T1 232 FNHTNGLTLIARAHQLV 248 **************976 PP >> STPPase_N Serine-threonine protein phosphatase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.3 3.6e-06 0.031 21 40 .. 26 45 .. 14 48 .. 0.83 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.6e-06 STPPase_N 21 qLsesEIraLCakAreiFLs 40 qLse++++ LC kA+ei+ + FUN_001214-T1 26 QLSEAQVKTLCDKAKEILSK 45 8****************866 PP >> zf-TAZ TAZ zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.7 4.8e-05 0.41 11 54 .. 21 62 .. 12 70 .. 0.79 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.8e-05 zf-TAZ 11 askCkakekekCkklkkCkkvkkllkHvksCkkkeCkvklCksl 54 +Ck+ ++ + + C+k+k++l++ ++ ++ +C+v++C ++ FUN_001214-T1 21 LMECKQLSE--AQVKTLCDKAKEILSKESNVQDVKCPVTVCGDV 62 567887774..345799**********99999989**9999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (313 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1163 (0.0455275); expected 510.9 (0.02) Passed bias filter: 1026 (0.0401644); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.43s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 3004.78 // Query: FUN_001215-T1 [L=971] Description: FUN_001215 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-18 66.2 1.8 6.2e-08 32.8 0.6 2.8 2 PLDc Phospholipase D Active site motif 2.2e-15 57.1 1.4 1.6e-10 41.3 0.4 3.0 2 PLDc_2 PLD-like domain 2.1e-09 38.2 4.4 9.3e-09 36.2 5.1 1.8 2 PX PX domain 9.8e-05 23.3 0.2 0.00035 21.5 0.2 2.1 1 PH PH domain ------ inclusion threshold ------ 0.051 14.2 0.2 16 6.2 0.0 2.7 3 DUF5061 17 kDa common-antigen outer membrane protein Domain annotation for each model (and alignments): >> PLDc Phospholipase D Active site motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.6 0.0 2.9e-11 1.5e-07 3 28 .] 449 474 .. 447 474 .. 0.95 2 ! 32.8 0.6 1.2e-11 6.2e-08 5 28 .] 789 812 .. 786 812 .. 0.95 Alignments for each domain: == domain 1 score: 31.6 bits; conditional E-value: 2.9e-11 PLDc 3 grlHrKivvvDdeiayiGgaNldgrs 28 +++H+K+vv+D ++a+iGg++l+ ++ FUN_001215-T1 449 WAHHEKLVVIDQKVAFIGGLDLCFGR 474 99*********************986 PP == domain 2 score: 32.8 bits; conditional E-value: 1.2e-11 PLDc 5 lHrKivvvDdeiayiGgaNldgrs 28 +H+K+++vDd+ ++iG+aN+++rs FUN_001215-T1 789 VHSKMMIVDDKTVIIGSANINDRS 812 7*********************97 PP >> PLDc_2 PLD-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 1.8e-05 0.09 24 97 .. 388 468 .. 373 478 .. 0.70 2 ! 41.3 0.4 3.2e-14 1.6e-10 2 121 .. 662 832 .. 661 836 .. 0.75 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 1.8e-05 PLDc_2 24 ivdaliaaakrGvkvriildsnksdsglvkkasqkeleellragvevrvykk.tl........gllHaKlliiDgktvivGSa 97 + + l++ a+ Gvk+ i++ ++ + + + s+ + +l + + +++v ++ ++ H+Kl++iD+k++++G+ FUN_001215-T1 388 LDNVLKRKAEAGVKIFILVYKEVE--LALSIDSAYTKAKLVSLHSNIKVLRHpDHitgagvvrWAHHEKLVVIDQKVAFIGGL 468 56778999************9332..2233333333334466666666765332245666666677***************86 PP == domain 2 score: 41.3 bits; conditional E-value: 3.2e-14 PLDc_2 2 ieliksAkksidiatyyf............tdkeivdaliaaakrGvkvriildsnks...................................... 47 +++i++Ak+ i+i +f +++++ ++ +a++ G ++i+ + FUN_001215-T1 662 VTAIQEAKHFIYIENQFFisslfidnvnneICQNLLWRIQRAHREGTTFKVIVVM--Pllpafegeigtatgrstgiithwnyrsicrgsqsller 755 5678899999999888888888888855555555577778899999888888888..445889999999999999999999888888877777776 PP PLDc_2 48 ......dsglvkkasqkeleel.lragvevrvykktlgllHaKlliiDgktvivGSaNltkrsl..elnlEllviikdkelaq 121 d + k+ s l++ ++g++v + l +H+K++i+D+ktvi+GSaN+++rsl +++ E+++i+kd+e+++ FUN_001215-T1 756 leklvgD--TSKYISFYGLRTHsVMYGTPVTE----LVYVHSKMMIVDDKTVIIGSANINDRSLlgRRDSEIAAIMKDREFVS 832 6544321..22233333333333445555443....3678****************************************987 PP >> PX PX domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.2 5.1 1.8e-12 9.3e-09 3 83 .. 99 194 .. 97 195 .. 0.83 2 ? -3.6 0.0 4.9 2.5e+04 15 39 .. 550 574 .. 550 586 .. 0.77 Alignments for each domain: == domain 1 score: 36.2 bits; conditional E-value: 1.8e-12 PX 3 tskkeessvkRrYsdFeeLhkkLlkkfp...........sliipplPskrllgrl....neefiekRrkaLeeylqrllqhpvlaesevlaeFLes 83 +++ ++++RrY++F +L+ +L + s+ +++lPs++l +r + + +ekR+k Le+ylq +l ++ + ++++ FLe+ FUN_001215-T1 99 SHGNFCWEIRRRYKHFLKLDAELFLHRVnhdvrhaarrqSRHLQHLPSRHLPKRPdmfaTTQKLEKRKKCLEKYLQTILDNSNYLNHKETLYFLEV 194 58899******************88888666776655544499999999444444667788889******************************97 PP == domain 2 score: -3.6 bits; conditional E-value: 4.9 PX 15 YsdFeeLhkkLlkkfpsliipplPs 39 ++dF +Lhk + ++ ++p +P FUN_001215-T1 550 HKDFCDLHKPYEDSVDRGLVPRMPW 574 6899999998888888778888885 PP >> PH PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.2 6.9e-08 0.00035 3 104 .. 208 314 .. 206 315 .. 0.82 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 6.9e-08 PH 3 keGwLlkkgsgkkk..............swkkryfvLkdgsllyykdkkskkskepkgsislk.gcevvevvasdkekrkfvFelrtsertgdrtl 83 +eG+L k+ +g++ w kr++ +kd+ + y +++ +ke +g++ ++ + + ++ +++ ++ + + +++r+l FUN_001215-T1 208 REGILRKRAGGHRFpagccsccsslswgLWDKRWLLVKDSFIAYLSPR----DKEVRGVVLMDkDFTFTHG--RKQTRVRNGLLV--Q--NQSRQL 293 79999999999999999999999999999*********999*******....9999998888526777754..334444444444..4..336*** PP PH 84 llqaeseeerkeWikaiqsai 104 ll++ +e+ +eW+kai +++ FUN_001215-T1 294 LLTCWTERKTREWMKAIIHVM 314 *****************9876 PP >> DUF5061 17 kDa common-antigen outer membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.0074 38 43 86 .. 19 64 .. 6 69 .. 0.87 2 ? 6.2 0.0 0.0031 16 47 91 .. 263 309 .. 253 310 .. 0.82 3 ? -3.9 0.0 4.2 2.1e+04 23 44 .. 812 833 .. 805 834 .. 0.85 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0074 DUF5061 43 ksvrvlleesyl.aasGreCrrltldtedqsa.evvlaCkgddkdk 86 +s+ v+ + s++ + sG C l d +d sa +v +aC +k+k FUN_001215-T1 19 SSISVVDQRSFIdSRSGSACIHLEEDEHDISAiDVTVACPSREKKK 64 799999999*98578**************9984789***9888875 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0031 DUF5061 47 vlleesylaasGreCr..rltldtedqsaevvlaCkgddkdkdWvmv 91 vl+++ + + Gr+ r l+ ++qs + l+C + k+++W+ + FUN_001215-T1 263 VLMDKDFTFTHGRKQTrvRNGLLVQNQSRQLLLTCWTERKTREWMKA 309 7888888888888765125689**********************875 PP == domain 3 score: -3.9 bits; conditional E-value: 4.2 DUF5061 23 dllstedtnslvtlddsefGks 44 ll+ +d++ + ++d ef +s FUN_001215-T1 812 SLLGRRDSEIAAIMKDREFVSS 833 5899999999999999999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (971 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 700 (0.0274026); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.38u 0.42s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 9191.85 // Query: FUN_001216-T1 [L=652] Description: FUN_001216 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.084 13.3 0.9 0.33 11.4 0.9 2.0 1 SBDS_C SBDS protein, C-terminal domain Domain annotation for each model (and alignments): >> SBDS_C SBDS protein, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.9 1.3e-05 0.33 5 59 .. 574 625 .. 572 631 .. 0.72 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 1.3e-05 SBDS_C 5 vtipakyagkalkeklkklgakvvekeewdsgslelvvlIdPglyreidellnk.e 59 + ++ +++k+ +e+ +++ +++wd+++ +++++d+ + + i e +++ + FUN_001216-T1 574 IILKEREEKKKARET----TEADNTDQSWDDDQIDVTCEVDAEAKDVIPEEISEnL 625 666644444443444....44455799*****************999999998844 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (652 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2535 (0.0992366); expected 510.9 (0.02) Passed bias filter: 504 (0.0197299); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 6304.13 // Query: FUN_001217-T1 [L=295] Description: FUN_001217 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-51 172.2 2.6 1.6e-19 69.9 0.0 3.0 3 Mito_carr Mitochondrial carrier protein Domain annotation for each model (and alignments): >> Mito_carr Mitochondrial carrier protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.1 0.3 2.2e-18 5.6e-14 21 90 .. 31 97 .. 16 101 .. 0.89 2 ! 49.1 0.1 2e-17 5.1e-13 8 91 .. 108 192 .. 105 195 .. 0.94 3 ! 69.9 0.0 6.4e-24 1.6e-19 4 94 .. 203 287 .. 200 289 .. 0.94 Alignments for each domain: == domain 1 score: 52.1 bits; conditional E-value: 2.2e-18 Mito_carr 21 lvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkk 90 ++ yP dv+Ktrlq+q+++ +k ++da+ k+vk+eG++glykG++++ l v + ++++ye ++ FUN_001217-T1 31 AILYPADVIKTRLQVQRTNVLYKG--TMDALFKTVKSEGLKGLYKGFMVSQLSVL-TGHFYVTSYEISRS 97 789****************99977..************************99998.77889999998776 PP == domain 2 score: 49.1 bits; conditional E-value: 2e-17 Mito_carr 8 sllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk.ildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkkl 91 +laGg+a+++++++++P++v+ +l++q++ +++ k k + ++ ++k++G+ g+y+G+l++l a +a+++++y + +l FUN_001217-T1 108 GFLAGGFAAVTEQFLANPVEVISQKLMIQGQGKSNVKLKgATRISLDLFKDQGMVGFYRGFLASLWTGALWSAVWWGSYGIYLDL 192 59*******************************9999999***************************************877665 PP == domain 3 score: 69.9 bits; conditional E-value: 6.4e-24 Mito_carr 4 sflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklllk 94 ++l + ++Gg++g+ a+++ +P+d+vKtrlq++++ks +++afk ++k+eG+r+l kG+l++++ +p++++++a+yetlkkl lk FUN_001217-T1 203 HLLIQSISGGLSGLNAAIIGNPFDIVKTRLQIEGEKS------MVKAFKDLLKKEGPRSLTKGMLASIISWIPSSVVMIAAYETLKKLSLK 287 5677899*****************************6......9******************************************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 565 (0.0221178); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2869.29 // Query: FUN_001218-T1 [L=340] Description: FUN_001218 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-43 149.5 0.3 1.8e-43 149.1 0.3 1.2 1 Galactosyl_T Galactosyltransferase ------ inclusion threshold ------ 0.26 10.6 0.0 0.35 10.2 0.0 1.1 1 Ntox11 Novel toxin 11 Domain annotation for each model (and alignments): >> Galactosyl_T Galactosyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 149.1 0.3 1.4e-47 1.8e-43 1 194 [. 113 300 .. 113 301 .. 0.96 Alignments for each domain: == domain 1 score: 149.1 bits; conditional E-value: 1.4e-47 Galactosyl_T 1 krRnaiRktWmnekeseinrikslFlvGlsakedkkvkelvmeeaklygDivvvdledtYenltlKtltlllyavskvpeaklilkiDdDvlvnpd 96 +rR+ iRktW+++++ ++ k++Fl+G+++ +++++k + +e+ ygD+v +d+++++ n+++K +++++ v++++ ++++lk DdDv+vn+ FUN_001218-T1 113 DRRQLIRKTWGAQHSIDTTEWKTVFLLGKNS-NEQEMKT-AKKESDIYGDMVHADYHEHFWNMSYKVAMGFEWSVKYCS-FHYLLKSDDDVFVNTF 205 59************9999*************.9999999.99************************************9.**************** PP Galactosyl_T 97 kLlsllkrelidpsessvygkvlkegavirkkkskwyvseeeykfseyptylsGtlYllsreavekllkaskhrkflkieDvlvGilaedlgisrk 192 ++ +l + p+++ +g+++ v+r+ vs++ey+ + y +y+sG +Y+lsr++vek + ++ lki+D+++G+la+++gi+++ FUN_001218-T1 206 GVMDYLSKF-TTPRKKLYTGNIMVGSVVLRRGRYG--VSPQEYNGTFYKPYCSGGGYILSRDVVEKFMGYFDFLRPLKIDDAYIGVLANRAGIKVI 298 ******998.99999*********98888887776..*********************************************************99 PP Galactosyl_T 193 dl 194 ++ FUN_001218-T1 299 HN 300 86 PP >> Ntox11 Novel toxin 11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 2.8e-05 0.35 242 317 .. 97 170 .. 55 178 .. 0.80 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 2.8e-05 Ntox11 242 eklglntrnskllgskeevmlkhdlWGlnlsgsGlGkklpvflpykeakkarkkgpkkgsdvsydvvesdGehshi 317 l l s +g+ + l ++ WG s k vfl k++++ k kk sd+ +d+v +d h h+ FUN_001218-T1 97 TSLYLLILVSTNVGNFDRRQLIRKTWGAQHSIDTTEWK-TVFLLGKNSNEQEMKTAKKESDIYGDMVHAD-YHEHF 170 555666666777788888889999************99.9***************************998.46665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (340 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 608 (0.0238011); expected 510.9 (0.02) Passed bias filter: 455 (0.0178117); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3321.99 // Query: FUN_001219-T1 [L=307] Description: FUN_001219 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-57 190.3 9.4 1.1e-21 76.8 0.3 3.3 3 Mito_carr Mitochondrial carrier protein ------ inclusion threshold ------ 0.073 13.6 2.3 5.2 7.7 0.3 2.5 2 CRF Corticotropin-releasing factor family Domain annotation for each model (and alignments): >> Mito_carr Mitochondrial carrier protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.8 0.2 1.2e-17 1.5e-13 21 92 .. 31 99 .. 28 103 .. 0.90 2 ! 67.7 0.4 6e-23 7.7e-19 6 92 .. 106 193 .. 101 196 .. 0.95 3 ! 76.8 0.3 8.8e-26 1.1e-21 6 93 .. 205 288 .. 200 291 .. 0.94 Alignments for each domain: == domain 1 score: 50.8 bits; conditional E-value: 1.2e-17 Mito_carr 21 lvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkkll 92 ++ yP +vKtrlq+q+k++ +k +daf k+++ eGirglykG+l++ ++ + +++t e++k FUN_001219-T1 31 ALLYPANLVKTRLQVQRKNALYKG--SFDAFVKVLRYEGIRGLYKGFLVSSFGLL-SGQFYITTLEMVKMRT 99 578*****************9987..9**************************99.7778888999998765 PP == domain 2 score: 67.7 bits; conditional E-value: 6e-23 Mito_carr 6 lasllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk.ildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkkll 92 ++ +laGgia ++++++t P+dv+ +l++q++ +s k k + ++++iv+ +G+rgly+G+l++l+ +ap++ai+++ty + +++ FUN_001219-T1 106 VRGFLAGGIASIVSQTITVPVDVISQKLMVQGQGVNSGKLKgASTIVREIVRCDGPRGLYRGYLISLMTYAPTSAIWWFTYGAYTRFV 193 5779*******************************9999999***************************************9998876 PP == domain 3 score: 76.8 bits; conditional E-value: 8.8e-26 Mito_carr 6 lasllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklll 93 + ++aG++ag++++++t+Pld+++trlq+ ++ks++ ++++f+++++eeG++gl kGl++++l ++p+++i+++ yet+k+l l FUN_001219-T1 205 FVLAVAGALAGFTTSTITNPLDIMRTRLQVGGGKSTY----VIHMFRTLLQEEGPTGLTKGLSARMLSMVPSSVIMVLGYETVKRLSL 288 55689*****************************999....*******************************************9865 PP >> CRF Corticotropin-releasing factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.1 0.0029 37 5 17 .. 122 134 .. 122 136 .. 0.93 2 ? 7.7 0.3 0.00041 5.2 5 17 .. 221 233 .. 221 234 .. 0.92 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0029 CRF 5 iDlPfhvLRqlle 17 i++P++v+ q+l+ FUN_001219-T1 122 ITVPVDVISQKLM 134 89**********9 PP == domain 2 score: 7.7 bits; conditional E-value: 0.00041 CRF 5 iDlPfhvLRqlle 17 i++P++++R++l+ FUN_001219-T1 221 ITNPLDIMRTRLQ 233 89*********96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (307 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 623 (0.0243883); expected 510.9 (0.02) Passed bias filter: 459 (0.0179683); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 3046.24 // Query: FUN_001220-T1 [L=229] Description: FUN_001220 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-05 24.8 49.1 0.0022 18.9 18.6 2.2 2 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 0.091 14.0 53.4 0.1 13.9 20.4 3.5 2 Toxin_TOLIP Snake toxin and toxin-like protein Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.0 22.6 2.4e-05 0.31 2 81 .. 21 112 .. 20 113 .. 0.91 2 ! 18.9 18.6 1.7e-07 0.0022 3 81 .. 121 207 .. 119 208 .. 0.86 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.4e-05 UPAR_LY6 2 glrCysClgessssccssgs..sCpkgdtqCvtttiklsgg..gkksslsvkgC...spscpelnetseig.....sltvtesccqsdlCns 81 +l+Cy+C g +++ + +s s +C+ g+++C + ++g + + ++C s+ c+ +++++ + ++ + +cc+sd+C + FUN_001220-T1 21 SLECYTCSGDQQQCNLESDSrsECSAGQNACSSLIRNSPSGmqFFFGCATENDCkaaSSVCSYMDKDKKKEpeemlGVSCNATCCSSDKCVK 112 69********999999999999***********999999886667778999*****9999*9999999999999999*************65 PP == domain 2 score: 18.9 bits; conditional E-value: 1.7e-07 UPAR_LY6 3 lrCysClgessssccssgssC.pkgdtqCvtttiklsgg..gkksslsvkgC..spscpelnetseig....sltvtesccqsdlCns 81 l+Cy+C +e+++++++ + +C ++ C++ t+++s + +++++ +kgC +++c + +++ + g + + scc++ Cn FUN_001220-T1 121 LQCYECNSETECANAKLQ-KCpDDDNYRCFKLTTEVSYKeaNVEVKTFSKGCirKEQCDPIKRNVFYGtcpnDENCHMSCCEGGMCNV 207 8*****888888888888.**5566689*99988888876689999**************9999998878777889999*******95 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 25.0 0.017 2.1e+02 1 71 [. 22 110 .. 22 111 .. 0.72 2 ? 13.9 20.4 7.9e-06 0.1 1 72 [] 121 206 .. 121 206 .. 0.80 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.017 Toxin_TOLIP 1 LkCytCeeeksnsnCl....ketkCsesekyCvttvtsa.............kskklisksCsssCeesss...elgvasvsvsCCqtdlC 71 L+CytC+ + ++C+ + ++Cs+ ++ C + + ++ ++ k+ s Cs +++++ e+ ++s +++CC++d C FUN_001220-T1 22 LECYTCSGDQ--QQCNlesdSRSECSAGQNACSSLIRNSpsgmqfffgcateNDCKAASSVCSYMDKDKKKepeEMLGVSCNATCCSSDKC 110 89****9988..566533337789************999999999888776644556666666665544440003444479*********9 PP == domain 2 score: 13.9 bits; conditional E-value: 7.9e-06 Toxin_TOLIP 1 LkCytCeeeksnsnCl..ketkCseseky.Cvttvtsa......kskklisksCsss..Ceessselgvas......vsvsCCqtdlCN 72 L+Cy+C++e+ +C k +kC+++++y C + +t++ + k+ sk C ++ C + + ++ ++ ++sCC+ +CN FUN_001220-T1 121 LQCYECNSET---ECAnaKLQKCPDDDNYrCFKLTTEVsykeanVEVKTFSKGCIRKeqCDPIKRNVFYGTcpndenCHMSCCEGGMCN 206 89********...67633789***99997698888888999998668999****76555**988887665444555689*********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (229 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1226 (0.0479937); expected 510.9 (0.02) Passed bias filter: 353 (0.0138188); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2274.43 // Query: FUN_001221-T1 [L=220] Description: FUN_001221 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.1e-10 39.3 46.8 3.3e-07 31.2 16.9 2.1 2 UPAR_LY6 u-PAR/Ly-6 domain 3.8e-05 24.8 16.6 3.8e-05 24.8 16.6 2.7 2 Toxin_TOLIP Snake toxin and toxin-like protein 0.00018 22.9 44.1 0.029 15.8 15.2 2.2 2 Activin_recp Activin types I and II receptor domain ------ inclusion threshold ------ 0.025 16.0 50.1 0.36 12.4 18.1 2.1 2 QVR Quiver family u-PAR/Ly-6-like domain Domain annotation for each model (and alignments): >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 21.9 9.2e-06 0.059 3 81 .. 21 102 .. 20 103 .. 0.76 2 ! 31.2 16.9 5.1e-11 3.3e-07 2 81 .. 109 197 .. 108 198 .. 0.96 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 9.2e-06 UPAR_LY6 3 lrCysClgessssccssgs..sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtesccqsdlCns 81 ++Cy+C+g+s + ++ + C g+++C++ +++ g+ + +gC +++c +++++ + ++ ++ cc +d Cn FUN_001221-T1 21 IQCYKCFGNSDVCNNNTLKsiDCLGGQDKCLSMKVERDGK----ETRLHGCatQNDCDTSEKSCASAasgRTNCETECCATDNCNM 102 79****988665555555589*****************77....344566666666666666555555556999***********6 PP == domain 2 score: 31.2 bits; conditional E-value: 5.1e-11 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseig....sltvtesccqsdlCns 81 +lrCy+C++ ss ++c++ s +C+ g++ C + + ++ +g +k + +kgC + c ++++ +g +++cc++dlCn FUN_001221-T1 109 KLRCYTCQSASSMDDCRQNSkamTCQHGEDRCGKFSAEVMAGDHKIMVYRKGCraQAACDKSKDLFGQGcgtdGSECDFKCCEGDLCNT 197 69***************9999**********************************9********999999999999************5 PP >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 25.8 0.023 1.4e+02 2 72 .] 22 101 .. 21 101 .. 0.67 2 ! 24.8 16.6 5.9e-09 3.8e-05 1 72 [] 110 196 .. 110 196 .. 0.81 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.023 Toxin_TOLIP 2 kCytCeeeks..nsnClketkCsesekyCvttvtsa.kskklisksCsss..Ceessselgvas.....vsvsCCqtdlCN 72 +Cy+C +++ n+n lk +C ++ C+++ +++ + k++ C+++ C +s+++ +a+ +++CC td CN FUN_001221-T1 22 QCYKCFGNSDvcNNNTLKSIDCLGGQDKCLSMKVERdG-KETRLHGCATQndCDTSEKSCASAAsgrtnCETECCATDNCN 101 9****877743377888999************999962.44444555544345544433332211222399*********9 PP == domain 2 score: 24.8 bits; conditional E-value: 5.9e-09 Toxin_TOLIP 1 LkCytCeeeksnsnCl...ketkCsesekyCvttvtsa....kskklisksCsss..Ceessselgva.s.....vsvsCCqtdlCN 72 L+CytC++++s ++C+ k+++C++ e+ C + +++ ++ +++k C ++ C +s+ +g++ ++CC+ dlCN FUN_001221-T1 110 LRCYTCQSASSMDDCRqnsKAMTCQHGEDRCGKFSAEVmagdHKIMVYRKGCRAQaaCDKSKDLFGQGcGtdgseCDFKCCEGDLCN 196 89*************84435679*********99999999976677779***98766998887777653235555889********9 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 20.8 3.1e-05 0.2 2 77 .. 22 102 .. 21 104 .. 0.81 2 ! 15.8 15.2 4.6e-06 0.029 1 77 [. 110 197 .. 110 199 .. 0.76 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3.1e-05 Activin_recp 2 kCy.Cetsk..Ceede.snvtcetd.gsCfssvekettgkikvvkkgclsreqdple...CktsnkpeqlnsrieCCktdfCNk 77 +Cy C +++ C+++ + + c +C s+ + +gk+ +gc +++++++ C+++++ ++ n ++eCC td CN FUN_001221-T1 22 QCYkCFGNSdvCNNNTlKSIDCLGGqDKCLSMKVE-RDGKE-TRLHGCATQNDCDTSeksCASAASGRT-NCETECCATDNCNM 102 56555555456*****98888877669****9999.9****.9*********66665577988888876.88***********6 PP == domain 2 score: 15.8 bits; conditional E-value: 4.6e-06 Activin_recp 1 lkCy.Cetsk....Ceedesnvtcetd.gsCfssvekettgkik..vvkkgclsre....qdpleCktsnkpeqlnsrieCCktdfCNk 77 l+Cy C++ + C+++++++tc+ C + + g++k v++kgc ++ +++l+++ + ++ + ++CC++d+CN FUN_001221-T1 110 LRCYtCQSASsmddCRQNSKAMTCQHGeDRCGKFSAEVMAGDHKimVYRKGCRAQAacdkSKDLFGQGCGTDGS-ECDFKCCEGDLCNT 197 68*99999888999************9988965555546666666699****9999754445555555555554.338**********7 PP >> QVR Quiver family u-PAR/Ly-6-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 24.0 0.00033 2.1 1 86 [] 21 101 .. 21 101 .. 0.90 2 ? 12.4 18.1 5.6e-05 0.36 1 86 [] 110 196 .. 110 196 .. 0.70 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00033 QVR 1 lkCYqCnseedpeCedefdekevelkeCseeatvCvkivekeeegeerviRgC.eseseedeeegckeessekkkleeCtCktdlCN 86 ++CY+C + ++ C++ ++ ++ +C ++ C+ ++ + ++g+e+ gC ++++ +++e++c +++s +++ e+ +C td+CN FUN_001221-T1 21 IQCYKCFGN-SDVCNN----NTLKSIDCLGGQDKCLSMKVE-RDGKETRLHGCaTQNDCDTSEKSCASAASGRTNCETECCATDNCN 101 89*****98.788988....9999*****************.99999******666667788999*99999999999989******9 PP == domain 2 score: 12.4 bits; conditional E-value: 5.6e-05 QVR 1 lkCYqCnseed.peCedefdekevelkeCseeatvCvkivek...eeegeerviRgCeseseedeeegckeessekkkleeC...tCktdlCN 86 l+CY+C+s+++ ++C++ ++++ +C++ ++ C k++ + +++ ++ +gC++++ d++++ + ++ +eC +C++dlCN FUN_001221-T1 110 LRCYTCQSASSmDDCRQ-----NSKAMTCQHGEDRCGKFSAEvmaGDHKIMVYRKGCRAQAACDKSKDLFGQGCGTDG-SECdfkCCEGDLCN 196 79******954157887.....78899999999********998667777777889*555555555444443333332.2344458******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (220 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1050 (0.0411039); expected 510.9 (0.02) Passed bias filter: 223 (0.00872969); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2198.02 // Query: FUN_001222-T1 [L=159] Description: FUN_001222 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-47 160.2 0.3 1e-46 160.0 0.3 1.0 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 160.0 0.3 4e-51 1e-46 77 220 .] 2 152 .. 1 152 [. 0.96 Alignments for each domain: == domain 1 score: 160.0 bits; conditional E-value: 4e-51 Trypsin 77 hpnynsdt.ldnDiallklkspvtlgdavrpiclpaassslavgttclvsGwGntkelg..lsdtlqevnvpvvsreecrsayggkvtdnmicaga 169 hp y ++ + +Diallkl++pv+++ +v+ +clp++ s +++g+ c+++GwG+ ++ g +++tlq+++vp+v+r++c+ +y g++ d+micag FUN_001222-T1 2 HPLYHKPIgMSHDIALLKLDRPVKVTRFVNLVCLPDNVSAPSEGKNCWITGWGRSHSVGgsSPNTLQQASVPIVGRNRCEWSYLGRIHDSMICAGL 97 88888887789*************************88888*************999999**********************99************ PP Trypsin 170 k.ggkdacqGDSGGPlvcsdg...eliGivswgkgcasgnkpgvytrvssyadwi 220 + gg d+cqGDSGGP+vc+ g +l+G++swg+gca++nk+gvy+rv+++++w+ FUN_001222-T1 98 DrGGIDSCQGDSGGPMVCETGgryYLQGVTSWGQGCARPNKYGVYARVKYVMKWL 152 *999**************************************************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (159 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 384 (0.0150323); expected 510.9 (0.02) Passed bias filter: 327 (0.0128009); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.21u 0.42s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1637.65 // Query: FUN_001223-T1 [L=271] Description: FUN_001223 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-26 92.7 0.0 3.9e-26 92.3 0.0 1.1 1 MAM MAM domain, meprin/A5/mu 2.8e-12 47.4 0.1 4.3e-12 46.8 0.1 1.3 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.3 0.0 3e-30 3.9e-26 1 157 [. 24 169 .. 24 170 .. 0.87 Alignments for each domain: == domain 1 score: 92.3 bits; conditional E-value: 3e-30 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssaeegqtarLlspllpasaksqClrFwyhmsgss..kgtlrvl 92 C+F+++ +Cg+tq+++d ++W r++++ s tgp++d + g+G+y+++e+s ++g++a L+ ++ + + +C++F+y m+g + +g lrvl FUN_001223-T1 24 CNFDRN-QCGFTQSKDDTFNWIRRRGStsSGGTGPQKDVS--GKGYYMYIEASGRKKGDNAKLEIKPGLSGM--ACISFYYNMRGGRnhVGILRVL 114 ******.*****************9998888999999999..***********99********997766555..5*********665236666666 PP MAM 93 lreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 + +g+e + sg+qg++W +a +t ++ v+fe+++g+g+++dia+D++++ ++C FUN_001223-T1 115 I--NGGE----AFVKSGHQGNNWLKADITSNE--PVSSVIFEGIVGRGYQSDIAIDEVTI--ETC 169 5..5555....56779*************999..7789*********************9..666 PP >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.8 0.1 3.4e-16 4.3e-12 1 48 [. 216 264 .. 216 271 .] 0.90 Alignments for each domain: == domain 1 score: 46.8 bits; conditional E-value: 3.4e-16 Trypsin 1 ivggeeaqagsfpwqvslqlssg.khfCGGslisenwvlTAaHCvsnas 48 ivgg ++++g++pwq++l+ s + +fCGGsl+ ++w++TA+HCv++as FUN_001223-T1 216 IVGGGDSSPGDWPWQGMLTSSPNgPVFCGGSLVAPQWLVTANHCVKGAS 264 89******************988999********************933 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (271 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 395 (0.0154629); expected 510.9 (0.02) Passed bias filter: 301 (0.0117831); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2680.76 // Query: FUN_001224-T1 [L=164] Description: FUN_001224 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-14 55.0 0.0 2.3e-14 54.5 0.0 1.2 1 Filamin Filamin/ABP280 repeat Domain annotation for each model (and alignments): >> Filamin Filamin/ABP280 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.5 0.0 8.8e-19 2.3e-14 4 93 .] 27 123 .. 24 123 .. 0.87 Alignments for each domain: == domain 1 score: 54.5 bits; conditional E-value: 8.8e-19 Filamin 4 askvkvsGpglepgvvgkpaeFtvdtrdaggekvtgfevev...tgpkgk..........kvevevednkdgtytvsYtptepgkytvsVkfngqh 86 ++++vsG+gl + vg+pa+F +t++ + + +++++ ++ + +++ve e +++ + vsY p+e+g+y +sV+++g h FUN_001224-T1 27 STQCSVSGEGLTLAFVGEPAKFILRTSGPDLL-F--LKLQItrmSK---DegdcltyltdPIPVEYECLGENLHSVSYYPKEEGEYHMSVTWKGTH 116 679************************99444.3..3688855433...3345999***999********************************** PP Filamin 87 ipgsPfk 93 ++gsPf+ FUN_001224-T1 117 VAGSPFV 123 ******5 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 517 (0.0202388); expected 510.9 (0.02) Passed bias filter: 476 (0.0186338); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1622.16 // Query: FUN_001225-T1 [L=637] Description: FUN_001225 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-117 391.6 4.1 9e-117 391.2 4.1 1.1 1 Peptidase_M13_N Peptidase family M13 7.3e-21 75.2 0.9 1.5e-20 74.2 0.3 1.9 2 Peptidase_M13 Peptidase family M13 ------ inclusion threshold ------ 0.13 12.4 0.3 0.88 9.6 0.0 2.2 2 Orbi_NS3 Orbivirus NS3 Domain annotation for each model (and alignments): >> Peptidase_M13_N Peptidase family M13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 391.2 4.1 1.1e-120 9e-117 1 382 [] 131 523 .. 131 523 .. 0.95 Alignments for each domain: == domain 1 score: 391.2 bits; conditional E-value: 1.1e-120 Peptidase_M13_N 1 PcdDFyeyaCGgWlknhpipadksswgtfeelreknekqlreileeaaasksdasae.ekakdlYkscmdteaieklglkplkellkeigga.. 91 PcdDFy+yaCG+W+k+ ip+++s+w +f++ +++n +l++ile ++ ++++++ +k+k+++++cm+++ ie +g++plk+l++ +g++ FUN_001225-T1 131 PCDDFYNYACGNWIKDSAIPPGHSKWTAFHQASDNNLMILKKILERSQLGINESAKVfTKVKNYFSACMNKTMIEDNGAQPLKKLIQYVGSWav 224 9************************************99*****987777766666647********************************778 PP Peptidase_M13_N 92 .......sawks.kfdlaellaklrrygvdslfglgvdpddknssrnilyldqpglglpdrdyylkerdeksaeileaykeylakllkllgade 177 +aw+ +++++ +l +++++ +lf ++v++dd+nss+ni++++q+g++l++rdyy++++ ++++l ayke+++k+ +llg + FUN_001225-T1 225 ndnatqvEAWSPeSWNFELALSRIHKLKSMPLFYMFVSADDRNSSQNIIQVQQAGITLSNRDYYFRNE---TDKVLVAYKEFMVKIGTLLGGEM 315 999997644343599***********766689********************************9664...4669***************9999 PP Peptidase_M13_N 178 eeaaaeaeevlafetklakisldreerrdpektynpmtlaelqklapgidwkaylkallpke..eseevivsepeylkklskllaetplrtlkn 269 ++ +++++e+++fe+kla+i ++e++r+ ek+y++mt+a+lq+lap+i+w +y+++++++ ++e+v+v++peylk++s+l+ t+ r+l+n FUN_001225-T1 316 NSTEEQMREIFQFEKKLAEIYEPKERLRNMEKIYHKMTVADLQQLAPAISWLDYMNTMFSSPvtHEEPVVVYTPEYLKNMSNLVIMTDRRILAN 409 98999****************************************************88887899*******************66******** PP Peptidase_M13_N 270 yliwrlvsslapylskefrdanfefyktlsgtk.qrprwkrcvslvnsllgealgrlyvkkyfpeeakakveelvenikeafkerleeldWmde 362 y++w+l++ l++ lsk+frda+ e+ k+ +g++ ++p+wk+cv ++++++g+a+g+ly+k+ ++ +k+++e+++++ik+af+ +l +++Wmde FUN_001225-T1 410 YMVWHLIKPLVDELSKPFRDASLELMKAEKGVEgKAPQWKTCVVKTDAVMGFATGYLYIKERSGKISKKEAEDMIAEIKKAFIGNLPHVNWMDE 503 *********************************666********************************************************** PP Peptidase_M13_N 363 etkkkAleKldaikvkigyp 382 etk +Al+K+++ +igyp FUN_001225-T1 504 ETKTQALKKVSSTFDMIGYP 523 *******************9 PP >> Peptidase_M13 Peptidase family M13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 1 8.5e+03 67 103 .. 319 355 .. 313 380 .. 0.65 2 ! 74.2 0.3 1.7e-24 1.5e-20 1 53 [. 582 634 .. 582 636 .. 0.97 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 1 Peptidase_M13 67 dedaeefkekakclieqfsevtepdktkavngsltlg 103 +e+++e+ + +k+l+e ++ + +++++ ++t+ FUN_001225-T1 319 EEQMREIFQFEKKLAEIYEPKERLRNMEKIYHKMTVA 355 5556666666777777777777777777766666654 PP == domain 2 score: 74.2 bits; conditional E-value: 1.7e-24 Peptidase_M13 1 NAyYqpeeneivfpaailqppfFdleypkavNyggiGaviaHEitHgfddqgv 53 NAyY++ +n i+fp +ilq pfFd+++p++vNyg++G+v++HE+tHgfdd g+ FUN_001225-T1 582 NAYYNSPNNYIAFPSGILQRPFFDPDFPQSVNYGAVGVVMGHELTHGFDDRGR 634 9*************************************************997 PP >> Orbi_NS3 Orbivirus NS3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.0 0.0001 0.88 61 121 .. 42 102 .. 30 127 .. 0.81 2 ? -0.1 0.1 0.098 8.3e+02 111 159 .. 442 489 .. 392 492 .. 0.77 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0001 Orbi_NS3 61 eqiipklekelrklkrkrlllklvelilavlalltslvmlvkelsetveknsevpawlksl 121 ++ + +le+++++ krk + + + + + +lal++++v++++ +s + k +vp +ks FUN_001225-T1 42 DEWLAQLERDYATAKRKHRSYWTSLERTLTLALIIFIVITISLASVLIFKKYHVPMIFKSS 102 67899************99999988888999999999999999999988855999998854 PP == domain 2 score: -0.1 bits; conditional E-value: 0.098 Orbi_NS3 111 nsevpawlkslsavvsvinllatvvllvlariekalkeqikrlkreivK 159 + + p+w k+ + + ++++at+ l++ +r+ k k++++ + ei K FUN_001225-T1 442 EGKAPQW-KTCVVKTDAVMGFATGYLYIKERSGKISKKEAEDMIAEIKK 489 3377899.888899999*********99999999998888887777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (637 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1376 (0.0538657); expected 510.9 (0.02) Passed bias filter: 929 (0.0363672); expected 510.9 (0.02) Passed Vit filter: 78 (0.00305344); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 6013.17 // Query: FUN_001226-T1 [L=72] Description: FUN_001226 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (72 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 417 (0.0163241); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 729.78 // Query: FUN_001227-T1 [L=537] Description: FUN_001227 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-05 25.1 19.0 0.00075 19.9 1.5 4.5 5 LRR_6 Leucine Rich repeat 0.00031 20.9 15.9 0.033 14.4 0.9 4.9 4 LRR_8 Leucine rich repeat 0.0019 18.9 15.3 0.031 15.0 1.3 3.9 4 LRR_4 Leucine Rich repeats (2 copies) ------ inclusion threshold ------ 0.062 13.9 13.1 40 5.5 0.0 6.9 7 LRR_1 Leucine Rich Repeat 0.4 9.4 4.7 0.62 8.8 4.7 1.3 1 CDC45 CDC45 2.5 7.3 9.4 4.2 6.6 9.4 1.3 1 NPR3 Nitrogen Permease regulator of amino acid transp Domain annotation for each model (and alignments): >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.8 1.9 8e+03 1 15 [. 198 212 .. 198 213 .. 0.82 2 ? -1.5 0.0 1.2 5.2e+03 4 23 .. 226 245 .. 224 246 .. 0.80 3 ! 8.4 0.1 0.00082 3.5 2 24 .] 252 274 .. 251 274 .. 0.90 4 ! 19.9 1.5 1.8e-07 0.00075 2 24 .] 280 302 .. 280 302 .. 0.98 5 ! 8.2 0.1 0.00095 4 6 23 .. 450 467 .. 445 468 .. 0.85 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.9 LRR_6 1 hnttLteLdLsgNdI 15 h ++L++L L +N + FUN_001227-T1 198 HLSNLRTLCLDNNPV 212 5689****9999976 PP == domain 2 score: -1.5 bits; conditional E-value: 1.2 LRR_6 4 tLteLdLsgNdIgDeGleaL 23 t++ L L+++ +++ G++++ FUN_001227-T1 226 TIQNLSLRNCYVNNMGAKMI 245 67779999998999999887 PP == domain 3 score: 8.4 bits; conditional E-value: 0.00082 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n +L +L+L +N+I+ eG+ La FUN_001227-T1 252 NKSLITLNLCYNKITCEGAGFLA 274 99****************97776 PP == domain 4 score: 19.9 bits; conditional E-value: 1.8e-07 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n+tL +L+L++N IgD G+++La FUN_001227-T1 280 NRTLLSLNLGSNLIGDNGASKLA 302 99*******************98 PP == domain 5 score: 8.2 bits; conditional E-value: 0.00095 LRR_6 6 teLdLsgNdIgDeGleaL 23 L+Ls N+++ +G+ea+ FUN_001227-T1 450 INLNLSRNKVDVTGVEAF 467 569*************98 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.9 7.7e-06 0.033 32 60 .. 183 211 .. 182 212 .. 0.92 2 ? 3.6 5.8 0.018 77 19 39 .. 247 267 .. 225 293 .. 0.66 3 ? 3.4 0.0 0.022 94 24 38 .. 446 460 .. 442 468 .. 0.66 4 ? -1.0 0.0 0.5 2.1e+03 25 37 .. 485 497 .. 479 499 .. 0.78 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 7.7e-06 LRR_8 32 LsnNllttlspgafsgLpsLrsLdLsgNr 60 L +N+l+tl +++++L++Lr+L L++N+ FUN_001227-T1 183 LQDNSLNTLATQVIAHLSNLRTLCLDNNP 211 7899*********************9997 PP == domain 2 score: 3.6 bits; conditional E-value: 0.018 LRR_8 19 gaFkglsnLkvLdLsnNlltt 39 +a + +++L +L+L +N++t FUN_001227-T1 247 QALTANKSLITLNLCYNKITC 267 3566789************95 PP == domain 3 score: 3.4 bits; conditional E-value: 0.022 LRR_8 24 lsnLkvLdLsnNllt 38 +++L L+Ls+N+ + FUN_001227-T1 446 NRALINLNLSRNKVD 460 567777777777755 PP == domain 4 score: -1.0 bits; conditional E-value: 0.5 LRR_8 25 snLkvLdLsnNll 37 ++L++++Ls+Nl FUN_001227-T1 485 TGLMRFSLSRNLF 497 5788899999975 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 1.3 7.3e-06 0.031 2 37 .. 172 213 .. 171 215 .. 0.84 2 ! 6.1 1.3 0.0048 20 4 37 .. 228 266 .. 225 268 .. 0.56 3 ! 9.3 1.9 0.00048 2 1 38 [. 253 295 .. 253 300 .. 0.76 4 ? 1.1 0.0 0.17 7.3e+02 3 13 .. 449 459 .. 439 466 .. 0.65 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 7.3e-06 LRR_4 2 nLetLdLsnNritdidp..ls.....kLpnLetLdLsgNnkit 37 +L+t+d++n+ ++d ++ l+ +L nL+tL L +Nn++t FUN_001227-T1 172 RLTTIDFWNTGLQDNSLntLAtqviaHLSNLRTLCL-DNNPVT 213 799**********99999855667757*******99.988875 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0048 LRR_4 4 etLdLsnNritdidp......lskLpnLetLdLsgNnkit 37 + L+L+n+ + + + l ++L tL+L N kit FUN_001227-T1 228 QNLSLRNCYVNNMGAkmigqaLTANKSLITLNLCYN-KIT 266 566666666666666554443445666777777333.654 PP == domain 3 score: 9.3 bits; conditional E-value: 0.00048 LRR_4 1 pnLetLdLsnNritdidp..ls....kLpnLetLdLsgNnkitd 38 ++L tL+L +N+it + l+ L +L+L g n+i d FUN_001227-T1 253 KSLITLNLCYNKITCEGAgfLAkglrMNRTLLSLNL-GSNLIGD 295 68************6555784455524666999999.6669876 PP == domain 4 score: 1.1 bits; conditional E-value: 0.17 LRR_4 3 LetLdLsnNri 13 L L+Ls N++ FUN_001227-T1 449 LINLNLSRNKV 459 44555555543 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 0.4 1.7e+03 2 20 .. 173 191 .. 172 193 .. 0.78 2 ? 3.8 0.0 0.036 1.6e+02 1 13 [. 201 213 .. 201 220 .. 0.89 3 ? 0.5 0.0 0.46 2e+03 2 13 .. 227 238 .. 226 247 .. 0.80 4 ? 5.5 0.0 0.0094 40 1 15 [. 254 268 .. 254 275 .. 0.80 5 ? 1.0 0.1 0.31 1.3e+03 2 14 .. 283 295 .. 282 304 .. 0.80 6 ? 2.7 0.0 0.083 3.5e+02 2 16 .. 449 463 .. 448 468 .. 0.75 7 ? 0.7 0.0 0.4 1.7e+03 2 17 .. 487 502 .. 486 505 .. 0.79 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.4 LRR_1 2 LeeLdLsnNnlsgllpesl 20 L+++d+ n+ l + ++++l FUN_001227-T1 173 LTTIDFWNTGLQDNSLNTL 191 999***9999977666655 PP == domain 2 score: 3.8 bits; conditional E-value: 0.036 LRR_1 1 nLeeLdLsnNnls 13 nL++L L+nN+ + FUN_001227-T1 201 NLRTLCLDNNPVT 213 8*********985 PP == domain 3 score: 0.5 bits; conditional E-value: 0.46 LRR_1 2 LeeLdLsnNnls 13 ++ L+L+n+ + FUN_001227-T1 227 IQNLSLRNCYVN 238 689******874 PP == domain 4 score: 5.5 bits; conditional E-value: 0.0094 LRR_1 1 nLeeLdLsnNnlsgl 15 +L +L+L++N+++ + FUN_001227-T1 254 SLITLNLCYNKITCE 268 699*********855 PP == domain 5 score: 1.0 bits; conditional E-value: 0.31 LRR_1 2 LeeLdLsnNnlsg 14 L +L+L +N +++ FUN_001227-T1 283 LLSLNLGSNLIGD 295 789******9964 PP == domain 6 score: 2.7 bits; conditional E-value: 0.083 LRR_1 2 LeeLdLsnNnlsgll 16 L L+Ls+N+ + FUN_001227-T1 449 LINLNLSRNKVDVTG 463 789******986554 PP == domain 7 score: 0.7 bits; conditional E-value: 0.4 LRR_1 2 LeeLdLsnNnlsgllp 17 L +++Ls+N +s + p FUN_001227-T1 487 LMRFSLSRNLFSPENP 502 67899******86665 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 4.7 0.00015 0.62 134 211 .. 360 418 .. 324 501 .. 0.46 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00015 CDC45 134 edeeeeeeddeeeeeeeeeeedeeeeeedeeeskkkrksesdeeeeeeddeeersrkrrrseesakklrkqlkkerre 211 ed+++ e++d ++++e +++e+e+ ++ ++ ++ ++ +++ ++ +++k +kq++ e +e FUN_001227-T1 360 EDKKSREKKDAQKKKETKKQEAEKAKKVAST------------------EAVNKGQSKGKKANTTKGDKKQQQPE-QE 418 1111111111111111111111111111111..................11111111111111111111111111.11 PP >> NPR3 Nitrogen Permease regulator of amino acid transport activity 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 9.4 0.001 4.2 44 104 .. 357 419 .. 339 458 .. 0.47 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.001 NPR3 44 wrkkkkkrkksskkkekk..skeeskkedssseeeaeeeesske.eeskekeeeeeeeeseded 104 k+ +k+++++k+ +kk +k++++++ ++ +++++ ++ +++ +++++++ ++++++ e+e+ FUN_001227-T1 357 VSKE-DKKSREKKDAQKKkeTKKQEAEKAKKVASTEAVNKGQSKgKKANTTKGDKKQQQPEQEQ 419 2222.23333222222220022222222222222222222222222222222222222222211 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (537 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2962 (0.115952); expected 510.9 (0.02) Passed bias filter: 1276 (0.0499511); expected 510.9 (0.02) Passed Vit filter: 252 (0.00986494); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.48u 0.40s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 5017.34 // Query: FUN_001228-T1 [L=480] Description: FUN_001228 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-218 725.1 0.0 4.9e-218 724.9 0.0 1.0 1 SBP56 56kDa selenium binding protein (SBP56) ------ inclusion threshold ------ 0.058 13.1 0.0 0.2 11.3 0.0 1.8 2 Lactonase Lactonase, 7-bladed beta-propeller 0.38 10.8 0.0 0.7 9.9 0.0 1.4 1 DUF5052 Domain of unknown function (DUF5052) Domain annotation for each model (and alignments): >> SBP56 56kDa selenium binding protein (SBP56) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 724.9 0.0 5.8e-222 4.9e-218 2 453 .] 8 472 .. 7 472 .. 0.99 Alignments for each domain: == domain 1 score: 724.9 bits; conditional E-value: 5.8e-222 SBP56 2 kedPgyasPkeaikapreklayvaalyagtgiekpDylavvdvdpesetyskvvsrvelpnlgdelhhsGWnaCsschedaskerryLilPglrss 97 ++Pgya+P +a+++pre+++y+ ++ ++tg +kpDyla+vdv+p s tys+v++r+++p++gdelhhsGWnaCssc++d+sk+r++Li+P+l+ss FUN_001228-T1 8 GCGPGYATPVDAMSGPREEIVYLPCIRTNTGLDKPDYLATVDVNPRSFTYSQVIHRLPVPYKGDELHHSGWNACSSCYGDSSKKRDRLIMPSLISS 103 589********************************************************************************************* PP SBP56 98 riyvvdtktdprkpelvkviepeevaektglsaphtvhCladgeilisalgdaeGegkGgillldsetfevkgrWekdrekqklayDfWyqlrknv 193 riy+ d+ tdpr+p+++k+i pe+va+ktgl + ht+hCla+ge++is+lg+++Geg+Gg+++ld+e f+vkgrWe ++++++yDfWyq+r+nv FUN_001228-T1 104 RIYIFDVGTDPRAPRIHKIISPEDVAQKTGLGFLHTTHCLASGEVMISSLGKPNGEGEGGFVILDGEKFDVKGRWECG-QPAPMGYDFWYQPRFNV 198 ****************************************************************************86.5799************* PP SBP56 194 lisseWgaPkafekGfdledveegkyGkrlhvwdleerkllqtidlgeegllplevrflhdPekaegfvgvaLsssvvrfykeedekweaekviei 289 +is+eWg Pka+++Gf++edve gkyG+rlhvwd++++ l+qtidlg g++ple+rflhdP++ +gf g+aLss++vrf+++e+e+w+ae+vi++ FUN_001228-T1 199 MISTEWGEPKALTQGFKVEDVETGKYGSRLHVWDWTTHALKQTIDLGV-GTIPLEIRFLHDPDQPQGFTGCALSSTIVRFFQNEEETWSAETVIKV 293 **********************************************96.67********************************************* PP SBP56 290 pakkvegealpelpglvtDilislDDrflyvsnWlhGdlrqydisdpkkPkltgqvrlGGllake...............eapavkgrkleggPqm 370 p+kkveg+alp++pgl+tDilislDD+fly+snWlhGd+rqydi dp++P+l+gqv++GG+++++ ++ +vkg+++eggPqm FUN_001228-T1 294 PPKKVEGWALPDMPGLITDILISLDDKFLYFSNWLHGDIRQYDIRDPRNPRLAGQVFIGGSIVSDgpvkvvqdselsgqpAPCYVKGKRVEGGPQM 389 ****************************************************************9*************988899************ PP SBP56 371 lqlslDGkrlyvtnsLysswdkqfypelvkkgsvllkidvdtekGglsldknflvdfgkepegparahevrykgGDassDiyi 453 +qlslDGkrlyvt+sLys wd+qfyp+l kkg++ll+idvdt +Ggl+l+ +f vdfg+ep+gp +ahevry+gGD+ssDi++ FUN_001228-T1 390 IQLSLDGKRLYVTTSLYSVWDNQFYPNLSKKGAMLLQIDVDTVNGGLTLNGDFCVDFGEEPDGPCLAHEVRYPGGDCSSDIWL 472 **********************************************************************************6 PP >> Lactonase Lactonase, 7-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 2.4e-05 0.2 245 290 .. 309 353 .. 255 355 .. 0.66 2 ? -1.7 0.0 0.21 1.8e+03 84 102 .. 385 403 .. 372 430 .. 0.64 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.4e-05 Lactonase 245 gaaeirvspdgkflyvSnRghdsiavfavdeaggtltlveevsteg 290 +i +s d+kfly Sn +h i +++ ++ ++ +l ++v ++g FUN_001228-T1 309 LITDILISLDDKFLYFSNWLHGDIRQYDI-RDPRNPRLAGQVFIGG 353 5679*************************.7767888887776665 PP == domain 2 score: -1.7 bits; conditional E-value: 0.21 Lactonase 84 egaspchlsvdedgrlllt 102 +g +++ ls+d ++ ++ t FUN_001228-T1 385 GGPQMIQLSLDGKRLYVTT 403 3333444444444444444 PP >> DUF5052 Domain of unknown function (DUF5052) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 8.2e-05 0.7 152 197 .. 370 412 .. 356 414 .. 0.75 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 8.2e-05 DUF5052 152 lGkPiavys.GenvsveaedlpkttklliDGkrLyiyRadytiydke 197 +G+P y+ G+ v e p++ +l +DGkrLy+ + y++ d++ FUN_001228-T1 370 SGQPAPCYVkGKRV----EGGPQMIQLSLDGKRLYVTTSLYSVWDNQ 412 56666666325555....4568999******************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (480 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 412 (0.0161284); expected 510.9 (0.02) Passed bias filter: 389 (0.015228); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4766.35 // Query: FUN_001229-T1 [L=128] Description: FUN_001229 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 878 (0.0343707); expected 510.9 (0.02) Passed bias filter: 686 (0.0268546); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1279.37 // Query: FUN_001230-T1 [L=554] Description: FUN_001230 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.4e-11 42.4 0.2 1.4e-10 41.3 0.2 1.6 1 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.3 0.2 5.6e-15 1.4e-10 1 53 [] 409 462 .. 409 462 .. 0.95 Alignments for each domain: == domain 1 score: 41.3 bits; conditional E-value: 5.6e-15 HLH 1 rreahnerERrRrdriNdafdeLrellP.tlppdkKlsKaeiLrlAieYIkqLq 53 rr a+n+rER R+++iN af+eL ++ + +l++dk +K+ iL +A++ I +L+ FUN_001230-T1 409 RRYANNARERMRVRDINGAFKELGRMCQlHLESDKPQTKLVILHQAVSVITSLE 462 7999**********************7779********************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (554 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 723 (0.028303); expected 510.9 (0.02) Passed bias filter: 379 (0.0148366); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5324.97 // Query: FUN_001230-T2 [L=690] Description: FUN_001230 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-11 41.9 0.2 1.9e-10 40.9 0.2 1.6 1 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.9 0.2 7.5e-15 1.9e-10 1 53 [] 545 598 .. 545 598 .. 0.95 Alignments for each domain: == domain 1 score: 40.9 bits; conditional E-value: 7.5e-15 HLH 1 rreahnerERrRrdriNdafdeLrellP.tlppdkKlsKaeiLrlAieYIkqLq 53 rr a+n+rER R+++iN af+eL ++ + +l++dk +K+ iL +A++ I +L+ FUN_001230-T2 545 RRYANNARERMRVRDINGAFKELGRMCQlHLESDKPQTKLVILHQAVSVITSLE 598 7999**********************7779********************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (690 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 660 (0.0258368); expected 510.9 (0.02) Passed bias filter: 363 (0.0142102); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.42s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6642.07 // Query: FUN_001230-T3 [L=456] Description: FUN_001230 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-10 41.2 0.2 3.6e-10 40.0 0.2 1.7 1 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.0 0.2 1.4e-14 3.6e-10 1 53 [] 306 364 .. 306 364 .. 0.93 Alignments for each domain: == domain 1 score: 40.0 bits; conditional E-value: 1.4e-14 HLH 1 rreahnerERrRrdriNdafdeLrellP......tlppdkKlsKaeiLrlAieYIkqLq 53 rr a+n+rER R+++iN af+eL ++ ++++++K +K+ iL +A++ I +L+ FUN_001230-T3 306 RRYANNARERLRVRDINGAFKELGRMCMmhlqgdKSNSNSKQTKLVILHQAVSVITSLE 364 7999**********************555999*9999******************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (456 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 900 (0.0352319); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4364.39 // Query: FUN_001231-T1 [L=129] Description: FUN_001231 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.055 13.8 0.2 0.065 13.6 0.2 1.2 1 Bap31 Bap31/Bap29 transmembrane region Domain annotation for each model (and alignments): >> Bap31 Bap31/Bap29 transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.2 2.5e-06 0.065 32 107 .. 12 87 .. 5 121 .. 0.87 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.5e-06 Bap31 32 kkifkllllsalsakvqialkillifllllflDavrevrkvsaeeekakaaeakvelsaesevqarkFyaQRNlYl 107 k i++ + l+ ls + + ++ l + ++l+++ vr+ + ++ +++++++++ + ++ + ++F + R +Yl FUN_001231-T1 12 KYIVHGRQLKDLSGTFFFSFFHLPVSVILCLVHEVRRSQDLDGSSSTNTQRQLGTFFVCSYMNKFKQFVSSRDMYL 87 6677777888888888888999999999999999**99999999999999999999999****************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 735 (0.0287728); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1322.79 // Query: FUN_001232-T1 [L=1654] Description: FUN_001232 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-53 179.4 20.7 1.4e-14 54.4 0.4 6.5 6 Myb_DNA-binding Myb-like DNA-binding domain 7.1e-44 148.3 10.2 1.2e-14 54.7 0.0 6.4 5 Myb_DNA-bind_6 Myb-like DNA-binding domain 3.5e-07 30.6 1.7 0.17 12.4 0.0 3.9 4 HTH_CHD1_Hrp3 ATP-dependent helicase CHD1-2/hrp3 HTH dom ------ inclusion threshold ------ 0.036 14.7 0.0 0.036 14.7 0.0 4.8 5 Myb_DNA-binding_2 Myb-like DNA-binding domain 2.1 9.1 3.5 36 5.1 0.1 3.1 3 SANT_DAMP1_like SANT/Myb-like domain of DAMP1 2.4 8.8 12.2 5.6e+02 1.2 8.3 4.6 2 Rap1_C TRF2-interacting telomeric protein/Rap1 - 3.4 8.2 6.6 2.2 8.8 0.6 3.3 3 Myb_DNA-binding_7 Myb-like DNA-binding domain Domain annotation for each model (and alignments): >> Myb_DNA-binding Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.031 1.1e+02 3 31 .. 367 397 .. 365 412 .. 0.81 2 ! 10.1 0.0 0.00027 0.98 22 44 .. 439 462 .. 431 463 .. 0.85 3 ! 26.7 0.1 1.7e-09 6.2e-06 1 44 [. 470 514 .. 470 516 .. 0.94 4 ! 43.3 0.1 1.1e-14 4e-11 1 45 [. 522 567 .. 522 568 .. 0.95 5 ! 54.4 0.4 3.9e-18 1.4e-14 1 45 [. 573 617 .. 573 618 .. 0.97 6 ! 51.8 1.0 2.4e-17 8.9e-14 1 43 [. 624 667 .. 624 669 .. 0.97 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.031 Myb_DNA-binding 3 pWtpeEdelLleaveklG..nrWkkIakllp 31 W + E ++L e+v++ n+ + I +++ FUN_001232-T1 367 VWNDKEKQCLAEGVRMQNleNKLSPILQKIR 397 6***************888798999999885 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00027 Myb_DNA-binding 22 rWkkI.akllpgRtdkqcknrwqn 44 +W+k ++p+Rt+ qc++ w+n FUN_001232-T1 439 DWDKLsGTYVPKRTAFQCRLQWCN 462 79999666999***********98 PP == domain 3 score: 26.7 bits; conditional E-value: 1.7e-09 Myb_DNA-binding 1 rgpWtpeEdelLleaveklGnrWkkIakllp.gRtdkqcknrwqn 44 r pWt+ Ed+ Ll++ + +W +Ia+ l+ +Rt+ +c +r+q+ FUN_001232-T1 470 RAPWTKVEDKMLLQLTKDPQQNWISIAQSLQtKRTPIHCYERYQR 514 569***************88***********99**********96 PP == domain 4 score: 43.3 bits; conditional E-value: 1.1e-14 Myb_DNA-binding 1 rgpWtpeEdelLleaveklG.nrWkkIakllpgRtdkqcknrwqny 45 + +Wtpe+d++Lle v+ G ++W+++a+ l gR + qc +r+ + FUN_001232-T1 522 KSKWTPEDDKQLLEVVRIVGlGNWRRVASFLEGRQGDQCLHRYTQT 567 679****************************************875 PP == domain 5 score: 54.4 bits; conditional E-value: 3.9e-18 Myb_DNA-binding 1 rgpWtpeEdelLleaveklGnrWkkIakllpgRtdkqcknrwqny 45 +g+W+++Ed lL+++ ek+G++W+k+++ +pgR++ qc++rw n FUN_001232-T1 573 KGKWSEDEDALLKKGMEKHGTCWNKVSEAVPGRSGPQCRERWVNA 617 79****************************************996 PP == domain 6 score: 51.8 bits; conditional E-value: 2.4e-17 Myb_DNA-binding 1 rgpWtpeEdelLleaveklG.nrWkkIakllpgRtdkqcknrwq 43 +gpWtp+ d++Lle + k+G ++W+kIa+ +++Rtd+qc rw FUN_001232-T1 624 KGPWTPQQDRKLLENIDKFGkGNWSKIARAVGNRTDNQCWRRWI 667 89*****************************************5 PP >> Myb_DNA-bind_6 Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.1 1e-08 3.6e-05 16 60 .] 433 481 .. 368 481 .. 0.86 2 ! 42.5 1.5 2.2e-14 8e-11 1 60 [] 473 533 .. 473 533 .. 0.97 3 ! 35.3 0.0 3.6e-12 1.3e-08 1 57 [. 525 581 .. 525 581 .. 0.94 4 ! 54.7 0.0 3.4e-18 1.2e-14 1 60 [] 576 635 .. 576 635 .. 0.98 5 ! 34.7 0.9 5.9e-12 2.2e-08 1 44 [. 627 670 .. 627 674 .. 0.92 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 1e-08 Myb_DNA-bind_6 16 ygn...dWkqIakel.grRtpkqcrerwkrklkpkikrspwskeedqrL 60 yg dW + + + ++Rt+ qcr w++ +p+++r+pw+k ed++L FUN_001232-T1 433 YGLegiDWDKLSGTYvPKRTAFQCRLQWCNFGHPDVNRAPWTKVEDKML 481 4434569****999989*************778************9987 PP == domain 2 score: 42.5 bits; conditional E-value: 2.2e-14 Myb_DNA-bind_6 1 WteeEdekLiqlvekygndWkqIakel.grRtpkqcrerwkrklkpkikrspwskeedqrL 60 Wt+ Ed+ L+ql + +++W +Ia+ l +Rtp +c er++r+l+ ++ +s+w++e d++L FUN_001232-T1 473 WTKVEDKMLLQLTKDPQQNWISIAQSLqTKRTPIHCYERYQRSLNKNLLKSKWTPEDDKQL 533 ***************************65*****************************998 PP == domain 3 score: 35.3 bits; conditional E-value: 3.6e-12 Myb_DNA-bind_6 1 WteeEdekLiqlvekyg.ndWkqIakel.grRtpkqcrerwkrklkpkikrspwskeed 57 Wt+e+d+ L+++v+ g +W+ +a++l g R+ qc r+ ++l + +++++ws+ ed FUN_001232-T1 525 WTPEDDKQLLEVVRIVGlGNWRRVASFLeG-RQGDQCLHRYTQTL-QMVRKGKWSEDED 581 *****************66*********88.************55.88********997 PP == domain 4 score: 54.7 bits; conditional E-value: 3.4e-18 Myb_DNA-bind_6 1 WteeEdekLiqlvekygndWkqIakel.grRtpkqcrerwkrklkpkikrspwskeedqrL 60 W+e+Ed +L + +ek+g W+++++++ g R+ qcrerw + l+pki ++pw++++d++L FUN_001232-T1 576 WSEDEDALLKKGMEKHGTCWNKVSEAVpG-RSGPQCRERWVNALDPKIDKGPWTPQQDRKL 635 ***************************66.****************************998 PP == domain 5 score: 34.7 bits; conditional E-value: 5.9e-12 Myb_DNA-bind_6 1 WteeEdekLiqlvekygn.dWkqIakelgrRtpkqcrerwkrklk 44 Wt+++d+kL++ k+g+ +W++Ia+++g+Rt +qc +rw+ l+ FUN_001232-T1 627 WTPQQDRKLLENIDKFGKgNWSKIARAVGNRTDNQCWRRWIV-LC 670 ****************976*********88**********99.54 PP >> HTH_CHD1_Hrp3 ATP-dependent helicase CHD1-2/hrp3 HTH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 1.9 6.8e+03 50 66 .. 474 490 .. 466 498 .. 0.70 2 ! 9.6 0.0 0.00036 1.3 18 44 .. 522 548 .. 508 551 .. 0.86 3 ! 5.0 0.1 0.0097 36 19 44 .. 574 598 .. 556 601 .. 0.84 4 ! 12.4 0.0 4.7e-05 0.17 21 44 .. 627 650 .. 619 654 .. 0.92 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 1.9 HTH_CHD1_Hrp3 50 lkltdkilleekkkPqa 66 k++dk+ll+ +k Pq FUN_001232-T1 474 TKVEDKMLLQLTKDPQQ 490 46677777777777765 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00036 HTH_CHD1_Hrp3 18 dveWgvedDskLLlGilkhGfGsWeki 44 + +W edD +LL + G+G+W+++ FUN_001232-T1 522 KSKWTPEDDKQLLEVVRIVGLGNWRRV 548 579*********************976 PP == domain 3 score: 5.0 bits; conditional E-value: 0.0097 HTH_CHD1_Hrp3 19 veWgvedDskLLlGilkhGfGsWeki 44 +W +D+ L G+ khG +W+k+ FUN_001232-T1 574 GKWSEDEDALLKKGMEKHGT-CWNKV 598 58*****************6.89887 PP == domain 4 score: 12.4 bits; conditional E-value: 4.7e-05 HTH_CHD1_Hrp3 21 WgvedDskLLlGilkhGfGsWeki 44 W ++D kLL i k+G G+W ki FUN_001232-T1 627 WTPQQDRKLLENIDKFGKGNWSKI 650 **********************99 PP >> Myb_DNA-binding_2 Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.34 1.2e+03 2 38 .. 472 504 .. 471 519 .. 0.81 2 ? -1.5 0.0 1.1 4e+03 24 39 .. 543 558 .. 523 571 .. 0.68 3 ? 14.7 0.0 9.7e-06 0.036 2 38 .. 575 607 .. 574 610 .. 0.89 4 ? 1.8 0.1 0.1 3.7e+02 2 38 .. 626 658 .. 625 665 .. 0.76 5 ? -4.6 2.5 7 2.6e+04 43 66 .. 735 758 .. 734 762 .. 0.74 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.34 Myb_DNA-binding_2 2 eWteedlelLkKqlvKhPvGtprRWEvIaeafkgrhk 38 +Wt+ + ++L ql+K P+ + W Ia+ ++++++ FUN_001232-T1 472 PWTKVEDKMLL-QLTKDPQ---QNWISIAQSLQTKRT 504 69998888885.6788885...779999999999987 PP == domain 2 score: -1.5 bits; conditional E-value: 1.1 Myb_DNA-binding_2 24 rRWEvIaeafkgrhkv 39 + W ++a +++gr++ FUN_001232-T1 543 GNWRRVASFLEGRQGD 558 4588888888888765 PP == domain 3 score: 14.7 bits; conditional E-value: 9.7e-06 Myb_DNA-binding_2 2 eWteedlelLkKqlvKhPvGtprRWEvIaeafkgrhk 38 +W+e++ lLkK++ Kh Gt W +++ea+ gr++ FUN_001232-T1 575 KWSEDEDALLKKGMEKH--GT--CWNKVSEAVPGRSG 607 7***************9..44..5********99986 PP == domain 4 score: 1.8 bits; conditional E-value: 0.1 Myb_DNA-binding_2 2 eWteedlelLkKqlvKhPvGtprRWEvIaeafkgrhk 38 +Wt + + L + K+ +G+ W +Ia a+ g+++ FUN_001232-T1 626 PWTPQQDRKLLENIDKFGKGN---WSKIARAV-GNRT 658 577777777777888887775...********.6665 PP == domain 5 score: -4.6 bits; conditional E-value: 7 Myb_DNA-binding_2 43 ikkaKelgekkpsdsdsfakflkk 66 i+kaK+ +++k++++++ ++ ++ FUN_001232-T1 735 ITKAKSREKEKAKKKQAEEEEARE 758 678999988888888877666555 PP >> SANT_DAMP1_like SANT/Myb-like domain of DAMP1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.0098 36 27 58 .. 471 502 .. 465 511 .. 0.86 2 ? 3.4 0.1 0.036 1.3e+02 18 42 .. 510 538 .. 500 543 .. 0.78 3 ? -1.6 0.1 1.3 4.6e+03 20 48 .. 564 595 .. 561 601 .. 0.70 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0098 SANT_DAMP1_like 27 edWtkeetdyLfelckeydlrfiviaDryele 58 + Wtk e ++L++l k+ + +i ia +++ FUN_001232-T1 471 APWTKVEDKMLLQLTKDPQQNWISIAQSLQTK 502 56**********************99877664 PP == domain 2 score: 3.4 bits; conditional E-value: 0.036 SANT_DAMP1_like 18 eeYeklLkd....edWtkeetdyLfelck 42 e Y++ L++ ++Wt e+ ++L+e+++ FUN_001232-T1 510 ERYQRSLNKnllkSKWTPEDDKQLLEVVR 538 667777777666589**********9987 PP == domain 3 score: -1.6 bits; conditional E-value: 1.3 SANT_DAMP1_like 20 YeklLkd...edWtkeetdyLfelckeydlrf 48 Y+++L+ +W+++e L + +++ + + FUN_001232-T1 564 YTQTLQMvrkGKWSEDEDALLKKGMEKHGTCW 595 777776654478****9888877666665555 PP >> Rap1_C TRF2-interacting telomeric protein/Rap1 - C terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.1 0.26 9.5e+02 48 58 .. 473 489 .. 449 513 .. 0.73 2 ? 1.2 8.3 0.15 5.6e+02 41 80 .. 620 666 .. 495 669 .. 0.93 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.26 Rap1_C 48 WteedDeaLr......s 58 Wt+ +D++L + FUN_001232-T1 473 WTKVEDKMLLqltkdpQ 489 *********85543332 PP == domain 2 score: 1.2 bits; conditional E-value: 0.15 Rap1_C 41 PknveGiWteedDeaLr.......sgderelkrlekkhgeerieaRr 80 Pk +G Wt+++D+ L +g+++++ r + +++++ +R+ FUN_001232-T1 620 PKIDKGPWTPQQDRKLLenidkfgKGNWSKIARAVGNRTDNQCWRRW 666 5556799********999***9999********************98 PP >> Myb_DNA-binding_7 Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 0.64 2.4e+03 1 42 [. 473 512 .. 473 516 .. 0.70 2 ? 0.9 0.1 0.18 6.4e+02 1 45 [. 525 567 .. 525 571 .. 0.78 3 ? 8.8 0.6 0.0006 2.2 1 45 [. 627 669 .. 627 671 .. 0.91 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.64 Myb_DNA-binding_7 1 WTReaDRaILtacqekGasqeTFqalsakLgnK.tpeevseRF 42 WT +D L+ + q+ + ++++ L +K tp eR+ FUN_001232-T1 473 WTKVEDKMLLQLTKD---PQQNWISIAQSLQTKrTPIHCYERY 512 888888877766654...4677899999998774566666666 PP == domain 2 score: 0.9 bits; conditional E-value: 0.18 Myb_DNA-binding_7 1 WTReaDRaILtacqekGasqeTFqalsakLgnKtpeevseRFkdL 45 WT e+D + L+ ++ G ++++++ L + + +R+ + FUN_001232-T1 525 WTPEDDKQLLEVVRIVGLG--NWRRVASFLEGRQGDQCLHRYTQT 567 ***********99998854..477777777777777777777765 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0006 Myb_DNA-binding_7 1 WTReaDRaILtacqekGasqeTFqalsakLgnKtpeevseRFkdL 45 WT +DR+ L+++ + G +++++ +gn+t ++ +R L FUN_001232-T1 627 WTPQQDRKLLENIDKFGK--GNWSKIARAVGNRTDNQCWRRWIVL 669 *****************6..569*****************98777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1654 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2758 (0.107966); expected 510.9 (0.02) Passed bias filter: 906 (0.0354668); expected 510.9 (0.02) Passed Vit filter: 207 (0.00810335); expected 25.5 (0.001) Passed Fwd filter: 100 (0.00391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.93u 0.40s 00:00:01.33 Elapsed: 00:00:00.47 # Mc/sec: 14297.91 // Query: FUN_001233-T1 [L=368] Description: FUN_001233 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-18 66.4 1.1 3.2e-18 66.4 1.1 2.2 2 HMG_box HMG (high mobility group) box 2.6e-12 47.7 0.5 2.6e-12 47.7 0.5 2.4 2 HMG_box_2 HMG-box domain 3.9e-06 27.2 0.2 1.8e-05 25.1 0.0 2.3 2 HMG_WDHD1 WDHD1 HMG box 7.3e-06 26.5 4.1 8.4e-06 26.3 2.5 2.0 1 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding 2.5e-05 24.9 2.4 5.5e-05 23.8 2.4 1.6 1 zf-met Zinc-finger of C2H2 type 0.00027 21.7 5.3 0.00027 21.7 5.3 2.9 1 ATG16 Autophagy protein 16 (ATG16) 0.00058 19.7 2.3 0.00058 19.7 2.3 2.1 2 DUF4763 Domain of unknown function (DUF4763) ------ inclusion threshold ------ 0.026 15.3 1.2 0.026 15.3 1.2 2.2 2 zf-C2H2_2 C2H2 type zinc-finger (2 copies) 0.033 14.7 0.0 0.075 13.6 0.0 1.7 1 DUF8078 Domain of unknown function (DUF8078) 0.044 14.8 3.4 0.17 12.9 3.4 2.0 1 GTP-bdg_M GTP-binding GTPase Middle Region 0.064 13.5 1.9 0.074 13.3 0.2 2.0 2 zf-U1 U1 zinc finger 0.27 11.0 3.9 0.13 12.0 1.3 1.8 2 CorA CorA-like Mg2+ transporter protein 1.1 9.7 5.2 0.83 10.0 0.7 2.9 3 DASH_Duo1 DASH complex subunit Duo1 1.1 8.9 10.0 2 8.1 3.6 2.2 2 DUF4407 Domain of unknown function (DUF4407) 1.7 9.2 0.0 1.7 9.2 0.0 3.9 4 SirC_C SirC C-terminal domain 1.8 9.1 7.0 0.15 12.6 1.1 2.2 3 DUF1664 Protein of unknown function (DUF1664) 2.5 8.5 7.3 10 6.5 0.2 2.6 3 Hydro_N_hd Hydrolase N-terminal helical domain 5.5 8.2 10.7 3.2 9.0 1.6 3.8 3 SlyX SlyX Domain annotation for each model (and alignments): >> HMG_box HMG (high mobility group) box # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.4 1.1 2.2e-21 3.2e-18 1 68 [. 59 126 .. 59 127 .. 0.98 2 ? -2.4 0.3 6.7 9.5e+03 17 40 .. 249 274 .. 242 289 .. 0.68 Alignments for each domain: == domain 1 score: 66.4 bits; conditional E-value: 2.2e-21 HMG_box 1 pkRplsaFflfsqeqraklkaenPdlknaeiskklgekWkelseeeKkkYeekaekekakyekampey 68 pk pl+ +++f++e+r+k++aen dl e++k+lg +W++l+ ++K+ Y e+aek+k++y+k+ ++y FUN_001233-T1 59 PKAPLTGYVRFLNEHREKIRAENQDLPFHEVTKILGNMWSQLPSQQKQCYLEEAEKDKERYMKELEQY 126 899***************************************************************99 PP == domain 2 score: -2.4 bits; conditional E-value: 6.7 HMG_box 17 aklkaenPdlk..naeiskklgekWk 40 +kl++ n++ + na +sk+++ + k FUN_001233-T1 249 RKLRKVNTEFEeqNAMLSKHIENMKK 274 66666666665446667777776655 PP >> HMG_box_2 HMG-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.7 0.5 1.8e-15 2.6e-12 2 71 .. 57 126 .. 56 127 .. 0.97 2 ? -1.7 0.4 4.9 6.9e+03 15 46 .. 241 273 .. 236 291 .. 0.65 Alignments for each domain: == domain 1 score: 47.7 bits; conditional E-value: 1.8e-15 HMG_box_2 2 kkpKaarnAYalFvqeeqpelkrknpvievaevskkcSekWrnlseeeKekYaekAredkerydremkty 71 + pKa+ Y+ F e +++++++n+ ++ ev+k +++ W +l +++K+ Y e+A dkery +e +y FUN_001233-T1 57 NAPKAPLTGYVRFLNEHREKIRAENQDLPFHEVTKILGNMWSQLPSQQKQCYLEEAEKDKERYMKELEQY 126 569***************************************************************9887 PP == domain 2 score: -1.7 bits; conditional E-value: 4.9 HMG_box_2 15 vqeeqpelkrknp.vievaevskkcSekWrnls 46 + + +el++ ++ e++e +S++ +n++ FUN_001233-T1 241 NKARENELRKLRKvNTEFEEQNAMLSKHIENMK 273 455666666665535666666666666655554 PP >> HMG_WDHD1 WDHD1 HMG box # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.0 1.3e-08 1.8e-05 1 50 [. 62 110 .. 62 111 .. 0.95 2 ? -2.3 0.1 4.6 6.6e+03 16 36 .. 258 278 .. 253 280 .. 0.71 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.3e-08 HMG_WDHD1 1 PktgFqLWLeenRsqileenPDlsdeadiiKegmsrfRsLsseeRkvWte 50 P tg+ +L+e R++i +en Dl+ ++++K ++ + L+s++++ + e FUN_001233-T1 62 PLTGYVRFLNEHREKIRAENQDLP-FHEVTKILGNMWSQLPSQQKQCYLE 110 89*********************5.99*******************9965 PP == domain 2 score: -2.3 bits; conditional E-value: 4.6 HMG_WDHD1 16 ileenPDlsdeadiiKegmsr 36 ++e+n ls + +K+gm++ FUN_001233-T1 258 FEEQNAMLSKHIENMKKGMEK 278 666666666666668999986 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 2.5 5.9e-09 8.4e-06 2 26 .. 159 183 .. 158 184 .. 0.96 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 5.9e-09 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlkSKkH 26 ++C +C+ yF+s ++ ++H+++KkH FUN_001233-T1 159 LFCSACNLYFNSPHNKREHMSGKKH 183 69*********************** PP >> zf-met Zinc-finger of C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 2.4 3.9e-08 5.5e-05 1 25 [] 159 183 .. 159 183 .. 0.97 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 3.9e-08 zf-met 1 fyCelCnvtftsesqlksHlqGKkH 25 ++C+ Cn +f+s+ + + H+ GKkH FUN_001233-T1 159 LFCSACNLYFNSPHNKREHMSGKKH 183 58*********************** PP >> ATG16 Autophagy protein 16 (ATG16) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 5.3 1.9e-07 0.00027 37 145 .. 193 310 .. 179 316 .. 0.75 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 1.9e-07 ATG16 37 enakleseaasatpsssqstsskkskkekeasass................qsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelek 116 +++k +++a+++ s++ +++++ +++s+ ++ ++ e++l +lr+ +e +++ l++ + ++++ +++le FUN_001233-T1 193 RAEKHAEKTANVKDSAEVKKTEE-------TTESQplqipldgdipifteeFLNYNKARENELRKLRKVNTEFEEQNAMLSKHIENMKKGMEKLEG 281 23333333333333222222222.......222222446677889999988889999*************************************** PP ATG16 117 klrederrlaeleaeraqleeklkdreee 145 + re+++++++l++ +a+l++ +++ +e FUN_001233-T1 282 ERREQQNEISALQRHLAKLRQVISRSFRE 310 ********************988876655 PP >> DUF4763 Domain of unknown function (DUF4763) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.3 1.4 1.9e+03 50 58 .. 116 124 .. 89 146 .. 0.51 2 ! 19.7 2.3 4.1e-07 0.00058 82 148 .. 236 302 .. 227 310 .. 0.93 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.4 DUF4763 50 lekiKqrvl 58 e+ ++ ++ FUN_001233-T1 116 KERYMKELE 124 111111111 PP == domain 2 score: 19.7 bits; conditional E-value: 4.1e-07 DUF4763 82 lelelltseqlellqLqrqnhkLrcqlselqqhlkasrksLkelrnslcqekkrlqklqkelnelde 148 ++l+ ++ + el++L++ n q + l++h + ++k +++l+ +++++++ + +lq+ l +l + FUN_001233-T1 236 EFLNYNKARENELRKLRKVNTEFEEQNAMLSKHIENMKKGMEKLEGERREQQNEISALQRHLAKLRQ 302 5677788999****************************************************99976 PP >> zf-C2H2_2 C2H2 type zinc-finger (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 1.2 1.8e-05 0.026 49 85 .. 157 193 .. 106 207 .. 0.77 2 ? -1.7 0.1 3.6 5.1e+03 81 90 .. 282 291 .. 254 304 .. 0.51 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 1.8e-05 zf-C2H2_2 49 ekleClvCekefkslealreHmkdkgHckiayeeeee 85 ++l C C+ f+s ++ reHm+ k+H+ + ++ ++ FUN_001233-T1 157 DDLFCSACNLYFNSPHNKREHMSGKKHFAVISSQMDR 193 4689************************985544333 PP == domain 2 score: -1.7 bits; conditional E-value: 3.6 zf-C2H2_2 81 eeeeekkeie 90 e++e+++ei+ FUN_001233-T1 282 ERREQQNEIS 291 3333333333 PP >> DUF8078 Domain of unknown function (DUF8078) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 5.3e-05 0.075 7 83 .. 284 360 .. 277 362 .. 0.84 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 5.3e-05 DUF8078 7 kedqelidkllWtiyiyklrlvdalkelrvPdfqdlvtvenvleflkiakilkkeklkkdaefigivksileketlp 83 +e q+ i +l + + + +++e+++P+ ++ +t e v f+ + +e+ k++ e+ +++k i+ + +p FUN_001233-T1 284 REQQNEISALQRHLAKLRQVISRSFREIQIPGEKEPITLESVDSFVGKLQLYIQENSKENLELTAKIKDIIASLDYP 360 4566667777777777777788999***********************9***************9999999877665 PP >> GTP-bdg_M GTP-binding GTPase Middle Region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 3.4 0.00012 0.17 20 70 .. 248 302 .. 243 309 .. 0.80 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.00012 GTP-bdg_M 20 lprLeglgkhlsrqgG....gigtrGpGetklEldrrlireriaklkkeLekvkk 70 l +L++ +++ + q++ +i ++ +G klE +rr+ ++ i+ l++ L+k+++ FUN_001233-T1 248 LRKLRKVNTEFEEQNAmlskHIENMKKGMEKLEGERREQQNEISALQRHLAKLRQ 302 556666677777776533334779****************************997 PP >> zf-U1 U1 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.2 5.2e-05 0.074 5 34 .. 160 187 .. 159 191 .. 0.89 2 ? -3.0 0.1 6.5 9.2e+03 29 36 .. 267 274 .. 266 275 .. 0.84 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 5.2e-05 zf-U1 5 yCdYCdiyLthDspsvRksHngGrkHkenv 34 +C C+ y +sp + H +G+kH + FUN_001233-T1 160 FCSACNLYF--NSPHNKREHMSGKKHFAVI 187 8999*****..9**************8766 PP == domain 2 score: -3.0 bits; conditional E-value: 6.5 zf-U1 29 kHkenvkd 36 kH+en k+ FUN_001233-T1 267 KHIENMKK 274 9***9985 PP >> CorA CorA-like Mg2+ transporter protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 2.6 3.7e+03 187 213 .. 102 128 .. 84 132 .. 0.73 2 ? 12.0 1.3 9e-05 0.13 116 168 .. 251 305 .. 242 356 .. 0.91 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.6 CorA 187 ddeqkeylrdlldrlerlleeldalre 213 +++++ yl+++ + er+++el+ +++ FUN_001233-T1 102 SQQKQCYLEEAEKDKERYMKELEQYQQ 128 444555788888888888888888875 PP == domain 2 score: 12.0 bits; conditional E-value: 9e-05 CorA 116 ldeivdrleellekleeeleeledel..edeednellrelaalrrsliklrrall 168 l++++ ++ee l++++e+ + + + e++e+ +e++al+r+l+klr++++ FUN_001233-T1 251 LRKVNTEFEEQNAMLSKHIENMKKGMekLEGERREQQNEISALQRHLAKLRQVIS 305 67889999999999************9999*********************9986 PP >> DASH_Duo1 DASH complex subunit Duo1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 1.8 2.5e+03 40 56 .. 90 106 .. 87 108 .. 0.82 2 ? 10.0 0.7 0.00058 0.83 3 32 .. 245 274 .. 245 281 .. 0.90 3 ? -1.4 0.0 2.2 3.1e+03 1 13 [. 292 304 .. 292 307 .. 0.85 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.8 DASH_Duo1 40 tntLLdkWirIlsqteh 56 t+ L + W+++ sq+++ FUN_001233-T1 90 TKILGNMWSQLPSQQKQ 106 6778899******9875 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00058 DASH_Duo1 3 ekEleqLrkineviekviesLkkaksnler 32 e+El++Lrk+n+ +e + L k +n+++ FUN_001233-T1 245 ENELRKLRKVNTEFEEQNAMLSKHIENMKK 274 68************************9987 PP == domain 3 score: -1.4 bits; conditional E-value: 2.2 DASH_Duo1 1 aLekEleqLrkin 13 aL++ l +Lr+++ FUN_001233-T1 292 ALQRHLAKLRQVI 304 6999999999987 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.4 0.015 21 206 251 .. 90 144 .. 35 150 .. 0.65 2 ? 8.1 3.6 0.0014 2 125 221 .. 205 346 .. 186 359 .. 0.65 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.015 DUF4407 206 k.........ntaklealraeiarleaekaaeeaaseaaiaaddGllaRleALdr 251 + ++++++ e a+ ++e+ +e ++ ++++a + + aR +AL++ FUN_001233-T1 90 TkilgnmwsqLPSQQKQCYLEEAEKDKERYMKELEQYQQTDAYKNFVARQKALKK 144 3666666666333444444444555556666666666679999*********987 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0014 DUF4407 125 kaqlaqa.....................lraelaelqaqiaalqaeidaaekeldelqkearcelegtkgtgttgvpGkGpeakekeeeldaaqae 199 k++ + + +++e + ++++++ +++++ ++e++e+++ +++++e+ ++g ++ e +e ++e+ a+q+ FUN_001233-T1 205 KDSAEVKkteettesqplqipldgdipiFTEEFLNYNKARENELRKLRKVNTEFEEQNAMLSKHIEN-MKKGMEK---LEGERREQQNEISALQRH 296 3333322444455555788888888888888888888888888889999999999999999998886.3334444...444578888899999999 PP DUF4407 200 laalqak............................ntaklealraeiarl 221 la+l++ + +++ +e +l FUN_001233-T1 297 LAKLRQVisrsfreiqipgekepitlesvdsfvgkLQLYIQENSKENLEL 346 99988887777766666666666666666666666444444444444444 PP >> SirC_C SirC C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.0 0.0012 1.7 3 17 .. 65 79 .. 64 84 .. 0.86 2 ? 1.2 1.0 0.39 5.6e+02 18 36 .. 98 116 .. 97 129 .. 0.72 3 ? -2.8 0.1 6.6 9.3e+03 18 26 .. 189 197 .. 188 198 .. 0.85 4 ? 0.7 0.2 0.56 7.9e+02 14 32 .. 250 268 .. 247 271 .. 0.86 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0012 SirC_C 3 eYldFLyecRekIKk 17 Y+ FL e RekI FUN_001233-T1 65 GYVRFLNEHREKIRA 79 7************75 PP == domain 2 score: 1.2 bits; conditional E-value: 0.39 SirC_C 18 lnldkeeKnelLkeildee 36 ++l++++K+ +L+e+ +++ FUN_001233-T1 98 SQLPSQQKQCYLEEAEKDK 116 5789999*****9997643 PP == domain 3 score: -2.8 bits; conditional E-value: 6.6 SirC_C 18 lnldkeeKn 26 +++d++eK+ FUN_001233-T1 189 SQMDRAEKH 197 899*****8 PP == domain 4 score: 0.7 bits; conditional E-value: 0.56 SirC_C 14 kIKklnldkeeKnelLkei 32 k+ k+n + ee+n+ L++ FUN_001233-T1 250 KLRKVNTEFEEQNAMLSKH 268 8999************875 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 5.4 7.7e+03 46 63 .. 89 106 .. 85 131 .. 0.58 2 ? -3.4 0.1 9.3 1.3e+04 48 56 .. 189 197 .. 179 218 .. 0.48 3 ? 12.6 1.1 0.00011 0.15 41 103 .. 242 304 .. 238 316 .. 0.88 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 5.4 DUF1664 46 vskqleqvseslaatKke 63 v+k l +++++l +++k+ FUN_001233-T1 89 VTKILGNMWSQLPSQQKQ 106 666666666666555443 PP == domain 2 score: -3.4 bits; conditional E-value: 9.3 DUF1664 48 kqleqvses 56 +q+++ ++ FUN_001233-T1 189 SQMDRAEKH 197 233222222 PP == domain 3 score: 12.6 bits; conditional E-value: 0.00011 DUF1664 41 davesvskqleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedv 103 +a+e+ ++l +v ++ +++ + Ls++i++++k +++ + +e ++e+ +++++++++++ + FUN_001233-T1 242 KARENELRKLRKVNTEFEEQNAMLSKHIENMKKGMEKLEGERREQQNEISALQRHLAKLRQVI 304 6677777899**********************************************9998765 PP >> Hydro_N_hd Hydrolase N-terminal helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.1 4.6 6.5e+03 155 160 .. 120 125 .. 88 149 .. 0.48 2 ? 6.5 0.2 0.007 10 59 96 .. 188 225 .. 176 228 .. 0.85 3 ? 5.8 0.3 0.012 17 80 139 .. 250 309 .. 240 345 .. 0.85 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 4.6 Hydro_N_hd 155 ealise 160 +++++ FUN_001233-T1 120 MKELEQ 125 111111 PP == domain 2 score: 6.5 bits; conditional E-value: 0.007 Hydro_N_hd 59 rrrfeaswnrengehPindsaevqrvtkslglqsaqLp 96 +++++++ ++ ++ ++dsaev++++++ ++q q+p FUN_001233-T1 188 SSQMDRAEKHAEKTANVKDSAEVKKTEETTESQPLQIP 225 5678888889999999*****************99987 PP == domain 3 score: 5.8 bits; conditional E-value: 0.012 Hydro_N_hd 80 evqrvtkslglqsaqLpkIavdLeniAaaLaeaqraaakeiaaLeaqLeaidaeigeale 139 + ++v+++ + q+a L k ++++ ++L+ +r+ ++ei+aL+++L+++ + i + ++ FUN_001233-T1 250 KLRKVNTEFEEQNAMLSKHIENMKKGMEKLEGERREQQNEISALQRHLAKLRQVISRSFR 309 56778888888888888888888888899999*******************999988766 PP >> SlyX SlyX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.3 0.076 1.1e+02 16 53 .. 245 282 .. 243 285 .. 0.83 2 ? 9.0 1.6 0.0023 3.2 20 47 .. 277 304 .. 276 319 .. 0.79 3 ? -0.6 0.0 2.1 3.1e+03 18 52 .. 321 355 .. 320 360 .. 0.81 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.076 SlyX 16 edtieeLndvvaeqqreidrlqrqlrllaerlkelees 53 e+ + +L +v +e +++ + l ++++++++ +++le + FUN_001233-T1 245 ENELRKLRKVNTEFEEQNAMLSKHIENMKKGMEKLEGE 282 67788899999999999999999999999999988876 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0023 SlyX 20 eeLndvvaeqqreidrlqrqlrllaerl 47 e+L + eqq ei++lqr+l++l++ + FUN_001233-T1 277 EKLEGERREQQNEISALQRHLAKLRQVI 304 566667789***************9977 PP == domain 3 score: -0.6 bits; conditional E-value: 2.1 SlyX 18 tieeLndvvaeqqreidrlqrqlrllaerlkelee 52 t+e+ + v + q i++ ++ +l+ ++k++ + FUN_001233-T1 321 TLESVDSFVGKLQLYIQENSKENLELTAKIKDIIA 355 56777778888899999999999999999998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (368 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2813 (0.110119); expected 510.9 (0.02) Passed bias filter: 879 (0.0344099); expected 510.9 (0.02) Passed Vit filter: 136 (0.00532394); expected 25.5 (0.001) Passed Fwd filter: 42 (0.00164416); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 3486.93 // Query: FUN_001234-T1 [L=179] Description: FUN_001234 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-07 30.8 0.0 3.4e-07 30.5 0.0 1.2 1 Peptidase_S24 Peptidase S24-like 2e-06 28.3 0.6 1.3e-05 25.7 0.2 2.0 2 Peptidase_S26 Signal peptidase, peptidase S26 Domain annotation for each model (and alignments): >> Peptidase_S24 Peptidase S24-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 0.0 2.6e-11 3.4e-07 24 101 .. 36 123 .. 22 142 .. 0.81 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 2.6e-11 Peptidase_S24 24 lpesllsepeklfalrvkGdSMepgikdgdlvlVd..kerearnGdivvarldg..eatvKrlkr....eggkirLks..lNpeyppi 101 ++ +++++++ ++ v SMep +++gdl++ ke+ +r G+ivv++++g +v+r+ + e+g i+++ +N++++++ FUN_001234-T1 36 WKGLMVVTGSESPIVVVLSGSMEPAFQRGDLLFLTnyKEDPIRVGEIVVFKVEGreIPIVHRVLKihekENGDIKFLTkgDNNSVDDR 123 5556678999999*********************98889****************866777766555557777777765667766665 PP >> Peptidase_S26 Signal peptidase, peptidase S26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.2 1e-09 1.3e-05 11 77 .. 32 98 .. 22 101 .. 0.75 2 ? 0.7 0.0 0.05 6.4e+02 138 164 .. 114 143 .. 105 146 .. 0.71 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 1e-09 Peptidase_S26 11 allla...llirtflfepykvpseSmeptllegdrlivnklsyklgepkrgDivvfkapedkkkdliKRV 77 al++ ++++ ++v s+Smep ++gd l+ yk ++++ g+ivvfk + ++++++ RV FUN_001234-T1 32 ALMIWkglMVVTGSESPIVVVLSGSMEPAFQRGDLLFLTN--YKEDPIRVGEIVVFKVEG-REIPIVHRV 98 3333344233333333448899****************97..****************98.999*99999 PP == domain 2 score: 0.7 bits; conditional E-value: 0.05 Peptidase_S26 138 lgdnrdnSlDSRyf...G..fvpkenivGkak 164 gdn nS D R + G ++++++vG+a+ FUN_001234-T1 114 KGDN--NSVDDRGLyapGqlWLQRKDVVGRAR 143 4666..9999995334554467999****997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 455 (0.0178117); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1827.04 // Query: FUN_001234-T2 [L=144] Description: FUN_001234 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-07 31.6 0.0 1.8e-07 31.4 0.0 1.1 1 Peptidase_S24 Peptidase S24-like 1.4e-06 28.8 0.6 7.5e-06 26.5 0.1 1.9 2 Peptidase_S26 Signal peptidase, peptidase S26 Domain annotation for each model (and alignments): >> Peptidase_S24 Peptidase S24-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 0.0 1.4e-11 1.8e-07 24 101 .. 36 123 .. 21 142 .. 0.81 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 1.4e-11 Peptidase_S24 24 lpesllsepeklfalrvkGdSMepgikdgdlvlVd..kerearnGdivvarldg..eatvKrlkr....eggkirLks..lNpeyppi 101 ++ +++++++ ++ v SMep +++gdl++ ke+ +r G+ivv++++g +v+r+ + e+g i+++ +N++++++ FUN_001234-T2 36 WKGLMVVTGSESPIVVVLSGSMEPAFQRGDLLFLTnyKEDPIRVGEIVVFKVEGreIPIVHRVLKihekENGDIKFLTkgDNNSVDDR 123 5556678999999*********************98889****************866777766555557778877766667777666 PP >> Peptidase_S26 Signal peptidase, peptidase S26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.1 5.8e-10 7.5e-06 11 77 .. 32 98 .. 21 101 .. 0.75 2 ? 0.7 0.0 0.05 6.4e+02 138 164 .. 114 143 .. 105 144 .] 0.71 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 5.8e-10 Peptidase_S26 11 allla...llirtflfepykvpseSmeptllegdrlivnklsyklgepkrgDivvfkapedkkkdliKRV 77 al++ ++++ ++v s+Smep ++gd l+ yk ++++ g+ivvfk + ++++++ RV FUN_001234-T2 32 ALMIWkglMVVTGSESPIVVVLSGSMEPAFQRGDLLFLTN--YKEDPIRVGEIVVFKVEG-REIPIVHRV 98 3333344233333333448899****************97..****************98.999**9999 PP == domain 2 score: 0.7 bits; conditional E-value: 0.05 Peptidase_S26 138 lgdnrdnSlDSRyf...G..fvpkenivGkak 164 gdn nS D R + G ++++++vG+a+ FUN_001234-T2 114 KGDN--NSVDDRGLyapGqlWLQRKDVVGRAR 143 4666..99999953345544679999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 566 (0.022157); expected 510.9 (0.02) Passed bias filter: 481 (0.0188295); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1431.67 // Query: FUN_001235-T1 [L=1249] Description: FUN_001235 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-73 247.8 6.7 2.1e-73 247.8 6.7 3.6 5 Sin3a_C C-terminal domain of Sin3a protein 2.7e-44 149.1 17.8 7.3e-20 70.9 0.0 4.6 4 PAH Paired amphipathic helix repeat 3.6e-40 136.5 0.0 3.6e-40 136.5 0.0 2.5 2 Sin3_corepress Sin3 family co-repressor 1.7e-08 35.1 8.1 0.048 14.4 0.0 5.7 5 PAH_ZNF598 ZNF598 PAH domain ------ inclusion threshold ------ 0.23 11.9 2.1 1 9.8 0.4 2.6 2 Tricorn_C1 Tricorn protease C1 domain 0.7 10.5 2.9 29 5.3 0.1 4.0 4 COX5A Cytochrome c oxidase subunit Va Domain annotation for each model (and alignments): >> Sin3a_C C-terminal domain of Sin3a protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 0.31 1.3e+03 31 84 .. 90 145 .. 78 149 .. 0.61 2 ? -3.8 2.2 2.3 1e+04 235 249 .. 222 236 .. 197 280 .. 0.59 3 ? -3.4 0.0 1.8 7.6e+03 35 77 .. 289 331 .. 277 335 .. 0.52 4 ? -3.1 0.1 1.5 6.3e+03 27 74 .. 390 456 .. 384 461 .. 0.57 5 ! 247.8 6.7 5e-77 2.1e-73 2 281 .] 838 1146 .. 837 1146 .. 0.86 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.31 Sin3a_C 31 veeeikrrkankvakelglisk..eledlgldleeeeeyYeqllelverlidGeid 84 v+ + + + +++ + l++++ l++++l++ ++ ++Y+ +l+ ++++ +id FUN_001235-T1 90 VHAQAQAQGQQQQFQRLKVEDAlsYLDQVKLQFGNQPQVYNDFLDIMKEFKSQSID 145 43333333344444444444220033455555588999********9999888877 PP == domain 2 score: -3.8 bits; conditional E-value: 2.3 Sin3a_C 235 eeeeeeeeeekaeke 249 +++ +++++++++++ FUN_001235-T1 222 QQQAQQKQQQQQQQQ 236 222222222111111 PP == domain 3 score: -3.4 bits; conditional E-value: 1.8 Sin3a_C 35 ikrrkankvakelgliskeledlgldleeeeeyYeqllelver 77 +k++k k a g+ +e+e + +++ ++e+Y+q+ +l+e+ FUN_001235-T1 289 QKEQKIIKEAAMQGTPLSEQEIYLREAKLANEVYKQVARLFEN 331 3333333333333333222222222335778888888888776 PP == domain 4 score: -3.1 bits; conditional E-value: 1.5 Sin3a_C 27 leeeveeeikrrkankvakelgliskeledlgldl...................eeeeeyYeqllel 74 ++ +++++ ++ +++++ + + ++ +d+ ++ +++e+Y+++l++ FUN_001235-T1 390 ITHQIRRNSNSVSSSPTHSQTKKSRSAIKDVSFAEaqqigtlsefsffekvkkaLKNNELYNNFLRC 456 5555555555555555555555554444444444455555555666666667777888888888876 PP == domain 5 score: 247.8 bits; conditional E-value: 5e-77 Sin3a_C 2 FanttiYvffrllqiLYeRLlkl.keleeeveeeikrrkankvakelgliskeledlgldleeeeeyYeqllelverlidGeidqsqfEdslRe 94 F n+++Y++frl+q+L+eRLlk+ +++ +e e ++++++k a+ + l k +++++l eeyY+++l+++++l+dG++d+++fEd++Re FUN_001235-T1 838 FLNNNWYLLFRLHQMLCERLLKMyQQSVMIAEGEASDKQQRKQATAIALRLKAPSEIDL-----EEYYPAFLDMIRNLLDGNMDSTNFEDTCRE 926 99*********************666666667788888888888888888666666665.....66**************************** PP Sin3a_C 95 mfgnkaYklyTidkliqalvkqlqtivsDsksqellelfekerskeet...taqd......eisyrkkaekllgkdenlfriewnkksk..evt 177 mfg +aY+++T+dkl+q++v+ql++iv+D+ + +++el+++e+ + +t +a++ e +y+k+ae+ll +den++++ ++k+++ +++ FUN_001235-T1 927 MFGVHAYIAFTMDKLVQNIVRQLHNIVTDDICGQVTELYQQEQGNLATggsSATQhtraagEAAYQKRAESLL-SDENCYKVVIHKDKNicRLS 1019 *******************************************766666652222446667************.**********77766559** PP Sin3a_C 178 iqlldkddltldddeltaeerwsyYvesYvls.eptegv.prsklkkpfLkrnlkkeeeeeeeeeeee.ekaeke................... 249 ++lld+dd++++d+ + e+w++Yve++v s e + +v ++ + k+ fL+r+++++++ ++ + ++e e+++ + FUN_001235-T1 1020 MELLDTDDTHSEDPV--EVEKWNEYVEKFVGSeEVSLEVkDHLQSKPIFLPRTVHSNSRVKSTTPNNEkESTT-Ndngsstdeaesegnnseke 1110 *************99..58***********441444444677778888******9888877777766533333.35899*************** PP Sin3a_C 250 ....kekeleveegleiriclnsyklvyepgteDvl 281 + +++eve+++e++++lnsyk+ +++g+eD+l FUN_001235-T1 1111 eeneEVEDMEVENSMECKLSLNSYKIRFVKGSEDYL 1146 *99988899999**********************96 PP >> PAH Paired amphipathic helix repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.9 0.0 1.7e-23 7.3e-20 1 45 [] 127 171 .. 127 171 .. 0.98 2 ! 39.5 3.8 1.1e-13 4.8e-10 1 45 [] 276 343 .. 276 343 .. 0.89 3 ! 45.1 1.7 1.9e-15 8.1e-12 2 45 .] 449 492 .. 448 492 .. 0.97 4 ? -2.5 0.0 1.4 6.1e+03 8 16 .. 856 864 .. 856 869 .. 0.77 Alignments for each domain: == domain 1 score: 70.9 bits; conditional E-value: 1.7e-23 PAH 1 evYneFLkiLndykqeiidiaevvarVseLlkghpdLlegFntFL 45 +vYn+FL+i++++k+++id+++v++rVs+L+kghp+L+ gFntFL FUN_001235-T1 127 QVYNDFLDIMKEFKSQSIDTPGVISRVSSLFKGHPELIVGFNTFL 171 79**************99**************************8 PP == domain 2 score: 39.5 bits; conditional E-value: 1.1e-13 PAH 1 evYneFLkiLndykqeiidiae.......................vvarVseLlkghpdLlegFntFL 45 ++Y+ FL+iL++y++e++ i+e v+ +V+ L+ +++dLl++F++FL FUN_001235-T1 276 DIYKAFLEILHTYQKEQKIIKEaamqgtplseqeiylreaklaneVYKQVARLFENQEDLLQEFSQFL 343 69**************55577777888888888888888888888**********************8 PP == domain 3 score: 45.1 bits; conditional E-value: 1.9e-15 PAH 2 vYneFLkiLndykqeiidiaevvarVseLlkghpdLlegFntFL 45 Yn+FL++L +++qe+i+++e+v+ +++l+++ +L+++F++FL FUN_001235-T1 449 LYNNFLRCLVLFNQEVISRSELVQLAANFLGKYAELFQWFKEFL 492 5**************99**************************8 PP == domain 4 score: -2.5 bits; conditional E-value: 1.4 PAH 8 kiLndykqe 16 ++L++y+q FUN_001235-T1 856 RLLKMYQQS 864 68*****97 PP >> Sin3_corepress Sin3 family co-repressor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 136.5 0.0 8.4e-44 3.6e-40 1 98 [] 525 620 .. 525 620 .. 0.98 2 ? -4.9 2.6 6 2.6e+04 25 61 .. 1085 1114 .. 1070 1136 .. 0.60 Alignments for each domain: == domain 1 score: 136.5 bits; conditional E-value: 8.4e-44 Sin3_corepress 1 krlgpsYrlLpkseqklkcsgrdelckevLNdewvsvptwasedsgsfvahrknqyeealfrvEderyeldlliesnkrtiklleklaekieems 95 kr+g+sYr+Lpks++++kcsgr++lc+evLNd+wvs+p+w sed+ f rk+qyee +fr+Eder+eld+++esn +ti++le +++k+++m FUN_001235-T1 525 KRYGTSYRALPKSYTQPKCSGRTALCREVLNDTWVSFPSW-SEDT-PFPGTRKTQYEEYIFRCEDERFELDVVLESNLSTIRVLEAIQKKLQRMP 617 689*************************************.****.6***********************************************9 PP Sin3_corepress 96 eee 98 +ee FUN_001235-T1 618 AEE 620 886 PP == domain 2 score: -4.9 bits; conditional E-value: 6 Sin3_corepress 25 lckevLNdewvsvptwasedsgsfvahrknqyeealf 61 ++++ Nd+ s +se ++s + e+ FUN_001235-T1 1085 EKESTTNDNGSSTDEAESEGNNSEKE-------EENE 1114 45666777777777776666642222.......2222 PP >> PAH_ZNF598 ZNF598 PAH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.0 1.1e-05 0.048 7 51 .. 114 158 .. 109 168 .. 0.90 2 ? 0.8 0.0 0.2 8.3e+02 7 35 .. 263 291 .. 260 296 .. 0.79 3 ? 2.0 0.1 0.088 3.7e+02 39 71 .. 318 346 .. 311 349 .. 0.70 4 ! 9.6 0.8 0.00035 1.5 6 65 .. 435 492 .. 432 498 .. 0.88 5 ! 6.4 0.0 0.0035 15 20 67 .. 898 948 .. 895 954 .. 0.75 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1.1e-05 PAH_ZNF598 7 lverirallkndeekfeeFkslsssfrqgeisardyidsvfslfg 51 +++++ ++n+++ +++F +++++f++++i++ i++v slf+ FUN_001235-T1 114 YLDQVKLQFGNQPQVYNDFLDIMKEFKSQSIDTPGVISRVSSLFK 158 5778899999**********************************8 PP == domain 2 score: 0.8 bits; conditional E-value: 0.2 PAH_ZNF598 7 lverirallkndeekfeeFkslsssfrqg 35 v++i++ ++++++ +++F ++ +++ FUN_001235-T1 263 YVNKIKNRFQGQPDIYKAFLEILHTYQKE 291 57788888888888888888888888765 PP == domain 3 score: 2.0 bits; conditional E-value: 0.088 PAH_ZNF598 39 ardyidsvfslfgtsseelgklvkeladLlpde 71 a++ +++v lf+ + + l++e+++ lpd+ FUN_001235-T1 318 ANEVYKQVARLFE----NQEDLLQEFSQFLPDA 346 6777888888886....3455677777777775 PP == domain 4 score: 9.6 bits; conditional E-value: 0.00035 PAH_ZNF598 6 alverirallkndeekfeeFkslsssfrqgeisardyidsvfslfgtsseelgklvkela 65 ++ e+++++lkn+ e ++ F f+q is +++++ + +g + +el + +ke++ FUN_001235-T1 435 SFFEKVKKALKNN-ELYNNFLRCLVLFNQEVISRSELVQLAANFLG-KYAELFQWFKEFL 492 589********66.79***************************998.7777777777775 PP == domain 5 score: 6.4 bits; conditional E-value: 0.0035 PAH_ZNF598 20 ekfeeFkslsssfrqgeisardyidsvfslfgtsse...elgklvkeladL 67 e + +F +++++ +g+++++ + d+++++fg ++ ++klv+++++ FUN_001235-T1 898 EYYPAFLDMIRNLLDGNMDSTNFEDTCREMFGVHAYiafTMDKLVQNIVRQ 948 56899***************************4332212336666666655 PP >> Tricorn_C1 Tricorn protease C1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.4 0.00024 1 4 35 .. 681 719 .. 676 731 .. 0.78 2 ? 0.1 0.1 0.27 1.1e+03 38 59 .] 908 929 .. 895 929 .. 0.87 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00024 Tricorn_C1 4 ewrqmFeeawrllrdnyydp.......dmkgvDWdavye 35 e + F+ +wr ++++yy + ++k+ D++++++ FUN_001235-T1 681 ESQRQFNKIWRDQNEKYYLKsldhqgiTFKQNDLKSMRS 719 34557*************997777777777777777665 PP == domain 2 score: 0.1 bits; conditional E-value: 0.27 Tricorn_C1 38 rplvpriatrdelsdllsemlg 59 r l++ ++ + + d +em+g FUN_001235-T1 908 RNLLDGNMDSTNFEDTCREMFG 929 7899999999**********97 PP >> COX5A Cytochrome c oxidase subunit Va # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.13 5.6e+02 61 89 .. 111 139 .. 106 147 .. 0.85 2 ? 5.3 0.1 0.0067 29 57 95 .. 256 294 .. 252 301 .. 0.89 3 ? -2.2 0.0 1.5 6.3e+03 64 85 .. 436 456 .. 434 465 .. 0.77 4 ? 0.4 0.0 0.23 9.8e+02 61 73 .. 602 614 .. 574 621 .. 0.87 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.13 COX5A 61 avRilEavkekvenkkqiYkyilqelkpv 89 a+ +l++vk + +n+ q+Y+ +l+ +k+ FUN_001235-T1 111 ALSYLDQVKLQFGNQPQVYNDFLDIMKEF 139 667899***************99988876 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0067 COX5A 57 dfalavRilEavkekvenkkqiYkyilqelkpvleeLgi 95 +f a+ ++ ++k++ + + +iYk++l+ l+ +e +i FUN_001235-T1 256 EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQKI 294 58899************************9999998777 PP == domain 3 score: -2.2 bits; conditional E-value: 1.5 COX5A 64 ilEavkekvenkkqiYkyilqe 85 ++E+vk+ +n++ Y+ +l FUN_001235-T1 436 FFEKVKKALKNNEL-YNNFLRC 456 79999988887776.9988865 PP == domain 4 score: 0.4 bits; conditional E-value: 0.23 COX5A 61 avRilEavkekve 73 ++R+lEa+++k + FUN_001235-T1 602 TIRVLEAIQKKLQ 614 7999999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1249 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3156 (0.123547); expected 510.9 (0.02) Passed bias filter: 796 (0.0311607); expected 510.9 (0.02) Passed Vit filter: 105 (0.00411039); expected 25.5 (0.001) Passed Fwd filter: 33 (0.00129184); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.57u 0.43s 00:00:01.00 Elapsed: 00:00:00.43 # Mc/sec: 11751.87 // Query: FUN_001236-T1 [L=206] Description: FUN_001236 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-33 115.6 2.6 1.7e-33 115.6 2.6 2.0 3 PEMT Phospholipid methyltransferase ------ inclusion threshold ------ 0.088 13.3 1.7 0.28 11.6 1.7 1.8 1 Steroid_dh 3-oxo-5-alpha-steroid 4-dehydrogenase Domain annotation for each model (and alignments): >> PEMT Phospholipid methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.41 5.2e+03 55 64 .. 21 30 .. 13 55 .. 0.55 2 ? -2.9 0.0 1.1 1.4e+04 4 24 .. 62 82 .. 60 85 .. 0.66 3 ! 115.6 2.6 1.4e-37 1.7e-33 3 104 .. 97 197 .. 95 198 .. 0.97 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.41 PEMT 55 eyvgstlgfl 64 + +++ ++++ FUN_001236-T1 21 KLWLAAACII 30 3333333322 PP == domain 2 score: -2.9 bits; conditional E-value: 1.1 PEMT 4 ilGlllialgillvlssieal 24 +l++++++lg++ ++ ea+ FUN_001236-T1 62 ALAFVICLLGLFRDYWFQEAI 82 667777777777777766655 PP == domain 3 score: 115.6 bits; conditional E-value: 1.4e-37 PEMT 3 lilGlllialgillvlssiealgefgtflgdfFgilmdklvtsgiYrvlnnPeyvgstlgflGlaLitgsvaglllallvllvvlialkfvEephl 98 i+G+++i++g++lvlss+++lg++gtflgd+Fg lm+k+ t+++++++nnP+y+gs++ flG++L s++glll++lv+++++ia+ +E p++ FUN_001236-T1 97 QIVGTVMIITGTVLVLSSTWSLGITGTFLGDYFGLLMNKRATNFPFNIMNNPMYWGSSMNFLGYSLRQCSPTGLLLTALVTTCYKIAIL-YEGPFT 191 477**************************************************************************************.****** PP PEMT 99 akiYgk 104 ++iY++ FUN_001236-T1 192 EQIYAE 197 ****97 PP >> Steroid_dh 3-oxo-5-alpha-steroid 4-dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.7 2.2e-05 0.28 12 112 .. 63 172 .. 58 204 .. 0.69 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.2e-05 Steroid_dh 12 vlfcvl.nGllqarylsyyqpy...aedllkkarlllgivlfvlgmliniksdiiLr.....elrkegetkykiprgglFelvsapnyfgEilewi 98 ++f+++ Gl++ ++++ a l+++ ++g+v+ ++g + s L g k + + F+ + p y g +++++ FUN_001236-T1 63 LAFVIClLGLFRDYWFQEAISSqpvAVALCTDSMQIVGTVMIITGTVLVLSSTWSLGitgtfLGDYFGLLMNKRATNFPFNIMNNPMYWGSSMNFL 158 45544325899998886543333348999999999999999999999999999999755532112234556677889******************* PP Steroid_dh 99 gyalvtkslaalaF 112 gy+l s +l FUN_001236-T1 159 GYSLRQCSPTGLLL 172 ****9888666543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (206 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 849 (0.0332355); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 2036.06 // Query: FUN_001236-T2 [L=237] Description: FUN_001236 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-33 115.2 2.6 2.5e-33 115.2 2.6 1.9 3 PEMT Phospholipid methyltransferase ------ inclusion threshold ------ 0.13 12.7 1.6 0.4 11.1 1.6 1.8 1 Steroid_dh 3-oxo-5-alpha-steroid 4-dehydrogenase Domain annotation for each model (and alignments): >> PEMT Phospholipid methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 0.46 5.9e+03 55 64 .. 52 61 .. 38 85 .. 0.60 2 ? -3.2 0.0 1.3 1.6e+04 4 24 .. 93 113 .. 91 116 .. 0.66 3 ! 115.2 2.6 1.9e-37 2.5e-33 3 104 .. 128 228 .. 126 229 .. 0.97 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.46 PEMT 55 eyvgstlgfl 64 + +++ ++++ FUN_001236-T2 52 KLWLAAACII 61 3333333322 PP == domain 2 score: -3.2 bits; conditional E-value: 1.3 PEMT 4 ilGlllialgillvlssieal 24 +l++++++lg++ ++ ea+ FUN_001236-T2 93 ALAFVICLLGLFRDYWFQEAI 113 667777777777777666655 PP == domain 3 score: 115.2 bits; conditional E-value: 1.9e-37 PEMT 3 lilGlllialgillvlssiealgefgtflgdfFgilmdklvtsgiYrvlnnPeyvgstlgflGlaLitgsvaglllallvllvvlialkfvEephl 98 i+G+++i++g++lvlss+++lg++gtflgd+Fg lm+k+ t+++++++nnP+y+gs++ flG++L s++glll++lv+++++ia+ +E p++ FUN_001236-T2 128 QIVGTVMIITGTVLVLSSTWSLGITGTFLGDYFGLLMNKRATNFPFNIMNNPMYWGSSMNFLGYSLRQCSPTGLLLTALVTTCYKIAIL-YEGPFT 222 477**************************************************************************************.****** PP PEMT 99 akiYgk 104 ++iY++ FUN_001236-T2 223 EQIYAE 228 ****97 PP >> Steroid_dh 3-oxo-5-alpha-steroid 4-dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 1.6 3.2e-05 0.4 12 112 .. 94 203 .. 89 235 .. 0.69 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 3.2e-05 Steroid_dh 12 vlfcvl.nGllqarylsyyqpy...aedllkkarlllgivlfvlgmliniksdiiLr.....elrkegetkykiprgglFelvsapnyfgEilewi 98 ++f+++ Gl++ ++++ a l+++ ++g+v+ ++g + s L g k + + F+ + p y g +++++ FUN_001236-T2 94 LAFVIClLGLFRDYWFQEAISSqpvAVALCTDSMQIVGTVMIITGTVLVLSSTWSLGitgtfLGDYFGLLMNKRATNFPFNIMNNPMYWGSSMNFL 189 45544325889888886543333348999999999999999999999999999999755532112234556677889******************* PP Steroid_dh 99 gyalvtkslaalaF 112 gy+l s +l FUN_001236-T2 190 GYSLRQCSPTGLLL 203 ****9888666543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (237 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 676 (0.0264631); expected 510.9 (0.02) Passed bias filter: 429 (0.0167939); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2398.54 // Query: FUN_001237-T1 [L=235] Description: FUN_001237 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (235 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 920 (0.0360149); expected 510.9 (0.02) Passed bias filter: 639 (0.0250147); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2389.58 // Query: FUN_001237-T2 [L=226] Description: FUN_001237 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (226 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 823 (0.0322177); expected 510.9 (0.02) Passed bias filter: 592 (0.0231748); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2242.84 // Query: FUN_001238-T1 [L=1221] Description: FUN_001238 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-57 190.4 15.3 6.4e-14 52.4 0.1 6.5 6 fn3 Fibronectin type III domain 2.9e-52 175.6 8.8 1.4e-12 48.4 0.0 6.2 6 Ig_3 Immunoglobulin domain 9.6e-50 167.1 0.0 1.3e-13 51.3 0.0 5.2 5 I-set Immunoglobulin I-set domain 1.6e-33 115.3 7.6 7.7e-10 39.4 0.0 6.6 6 ig Immunoglobulin domain 1.1e-30 106.1 5.4 8.6e-08 32.8 0.0 6.5 7 Ig_2 Immunoglobulin domain 7.9e-16 58.4 2.4 0.0089 16.5 0.1 6.5 5 C2-set_2 CD80-like C2-set immunoglobulin domain 1.4e-14 54.9 7.3 0.00018 22.6 0.0 6.3 6 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domai 9.3e-10 39.2 0.0 0.56 11.1 0.0 4.9 5 FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain 3.2e-09 37.4 2.4 0.77 10.5 0.0 6.1 6 V-set Immunoglobulin V-set domain 1.6e-07 31.6 0.7 0.025 15.0 0.2 4.3 4 fn3_4 Fibronectin-III type domain 8.2e-06 26.5 0.0 0.017 15.9 0.0 4.9 4 Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain 1.5e-05 25.5 0.0 0.00021 21.8 0.0 2.8 2 Fn3_VIN3 VIN3-like, fibronectin type-III domain 3.2e-05 24.3 0.3 4.2 7.9 0.0 4.7 4 C2-set_3 Butyrophilin subfamily 3 member A2-like, 4.2e-05 24.3 0.2 16 6.3 0.8 4.6 5 Interfer-bind Interferon-alpha/beta receptor, fibronect 6.8e-05 23.3 5.1 1.1 9.8 0.0 4.7 4 Ig_RIMBP2 RIMBP2-like, immunoglobulin-like domain 0.00087 20.0 4.4 5.9 7.7 0.0 5.6 5 Ig_Rha78A_N Rha78A-like, N-terminal immunoglobulin do 0.003 18.2 0.7 0.069 13.8 0.0 3.3 3 Fn3_R-PTP-O R-PTP-O-like, fibronectin type III domain ------ inclusion threshold ------ 0.091 13.2 0.1 5.8 7.4 0.0 2.7 2 Ig_PDGFR_d4 Platelet-derived growth factor receptor I 0.26 12.0 0.2 37 5.0 0.0 4.2 5 SusE SusE outer membrane protein Domain annotation for each model (and alignments): >> fn3 Fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.1 0.1 9.3e-15 1.2e-11 2 80 .. 412 493 .. 411 497 .. 0.88 2 ! 52.4 0.1 4.7e-17 6.4e-14 2 83 .. 506 597 .. 505 598 .. 0.92 3 ! 23.4 0.0 5.2e-08 7e-05 10 77 .. 616 691 .. 608 698 .. 0.81 4 ! 29.2 0.7 8.2e-10 1.1e-06 2 78 .. 716 801 .. 715 807 .. 0.82 5 ! 37.5 0.1 2.2e-12 2.9e-09 1 83 [. 819 917 .. 819 918 .. 0.82 6 ! 8.4 0.1 0.0025 3.4 3 81 .. 924 1018 .. 923 1021 .. 0.78 Alignments for each domain: == domain 1 score: 45.1 bits; conditional E-value: 9.3e-15 fn3 2 aPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne....tvpgsretsvtltgLkpgteYevrVqavngaGegeesep 80 +Ptnl + + +s+s+++sW+pp gn +i+gY v+y+ +++ ++ ++ +t +++++L +Y++ V+a+ + g++s FUN_001238-T1 412 PPTNLVAVALSSSSIVLSWSPPtPGNFTIQGYVVHYQRQGGsekqEILDN-KTHFEFKNLYGFINYTFFVRAYGDL-LGRQSTS 493 9*********************99999999********888888899999.799******************8664.5555554 PP == domain 2 score: 52.4 bits; conditional E-value: 4.7e-17 fn3 2 aPtnltvtdvtstsltvsWtpp...dgngpitgYeveyrpkne........tvpgsr.etsvtltgLkpgteYevrVqavngaGegeeseplev 83 +P+ ++vt+ t++sl + W+pp ++ng i +Y++e+r+++ +vpg+ + t++gL g++Y ++V a +++G+g++s+p+++ FUN_001238-T1 506 PPEIVNVTSLTPDSLDLAWQPPpklSQNGVIIKYSIEWRQEGRrgwqasttEVPGHFlH--KTINGLAMGKTYIIKVCAGTAKGWGKWSQPVTA 597 7999*********************99*************8888787777888888543..89****************************986 PP == domain 3 score: 23.4 bits; conditional E-value: 5.2e-08 fn3 10 dvtstsltvsWtpp.dgngpitgYeveyrpkne........tvpgsretsvtltgLkpgteYevrVqavngaGegee 77 ++++t l+v+ pp g++ +++Y++ y ++ + ++ ++++ ltgL+pg eY ++V a g+ g++ FUN_001238-T1 616 HQNATALQVRLLPPrYGKELVKEYRLFYVRLKSseteqgplIIEKH-HKEYLLTGLRPGAEYLIKVMAWDGQRLGQP 691 67999*********99999999****99984444556778766666.899*****************9999866655 PP == domain 4 score: 29.2 bits; conditional E-value: 8.2e-10 fn3 2 aPt..nltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne......tvpgsretsvtltgLkpgteYevrVqavngaGeg.ees 78 +P+ nl++ ++ts+ ++W+ p ++ + + Y+v+y+ k + t++ + ++s l+gL+ + Y + Vq++ + + +s FUN_001238-T1 716 PPRpiNLRCAVESPTSILLTWESPiSSAHRTSYYTVKYHLKRSpnprqkTLTVE-TKSIILNGLRSERVYDIFVQSHYKTKTSrFQS 801 566669******************99999999********88887777766666.789*****************776653332444 PP == domain 5 score: 37.5 bits; conditional E-value: 2.2e-12 fn3 1 saPtnltvtdvtstsltvsWtpp.dgngpitgYeveyrpkne..............tvpgsr..etsvtltgLkpgteYevrVqavngaGegeese 79 s+P+n++++ + +s++v+W++p ++ng++ +Ye+++++ ++ + g+r + l +Lk +t + ++++a n++G+g++ + FUN_001238-T1 819 SPPRNVNFKYESHNSIEVTWEKPtETNGQLISYEIYFTNNSSlpdsewsfrpvrtgFI-GNRneKMYRRLLQLKLDTPFYFKIRAENEKGYGPFCK 913 79*********************************99985555555677666666433.23234555899**********************9877 PP fn3 80 plev 83 +ev FUN_001238-T1 914 TIEV 917 7765 PP == domain 6 score: 8.4 bits; conditional E-value: 0.0025 fn3 3 Pt.nltvtdvtstsltvsWtpp..dgngpitgYeveyrp.kne..........tvpgsretsvtltgLkpgteYevr...VqavngaGeg.ees 78 P+ n++ t +++ +++sW p +++ ++++++ +++ k + vp+ + s+ +t+ + ++Yev+ V+a g+ ++s FUN_001238-T1 924 PRvNVSYTIISPKLVQLSWACPnnFNSAAVKRFTILITNnK-NdpegsweklsFVPSK-KCSMAVTKTIAVSQYEVHfmkVRAEYGEKTPgKWS 1015 555788888999999********76678888****999953.4477889999999999.899**************976677766654334666 PP fn3 79 epl 81 + + FUN_001238-T1 1016 NII 1018 555 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 0.0 1e-10 1.3e-07 1 77 [. 26 107 .. 26 108 .. 0.87 2 ! 47.8 0.0 1.6e-15 2.1e-12 6 78 .] 131 201 .. 128 201 .. 0.88 3 ! 45.1 0.1 1.1e-14 1.5e-11 7 77 .. 231 296 .. 227 297 .. 0.90 4 ! 48.4 0.0 1e-15 1.4e-12 1 78 [] 313 390 .. 313 390 .. 0.91 5 ? 1.7 0.1 0.38 5.2e+02 18 44 .. 719 742 .. 709 772 .. 0.65 6 ? -1.6 0.1 4.1 5.5e+03 28 40 .. 831 843 .. 795 866 .. 0.63 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 1e-10 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppp.titWykngkelssgstskr.....sssssnstLtisnvtredsGtYtCvAs 77 +P + +ps+tv++ +e+v L+C + g+++ +i W+k+g++++++++ +r + n L i++ + G+Y+C As FUN_001238-T1 26 PPYFIHEPSDTVLRRNEPVALNCFVGGSSASnNIVWKKDGRPIDTNEDVRRkiapnGTLLFNKILDIKD-AKPYVGEYQCFAS 107 899999*******************999999***********666666655688888888888899999.55569*****997 PP == domain 2 score: 47.8 bits; conditional E-value: 1.6e-15 Ig_3 6 vspsstvveegesvtLtCeaegnppp.titWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 +p++t++ g+ ++++C++++ pp ti+W+kng lss+++ ++++L+i+++t++d+G+Y+C+A+N FUN_001238-T1 131 YEPQNTTTWIGSVAQFSCQIRNALPPaTIEWRKNGMLLSSNERV---LIFDRGVLQIKETTKSDEGEYSCTARN 201 68999999************7666666*********86665555...8*************************9 PP == domain 3 score: 45.1 bits; conditional E-value: 1.1e-14 Ig_3 7 spsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAs 77 +p +++v++g++ +L C a+g+p+p++tW+k + + + +s + s+L++ nvt++d G+++C+As FUN_001238-T1 231 TPHNVTVVQGDETVLDCAATGDPTPSVTWKKLTG---NPRVF--DTSPGISNLEFVNVTENDGGEFKCQAS 296 789999*************************999...42222..7899**********************8 PP == domain 4 score: 48.4 bits; conditional E-value: 1e-15 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 +P++t p + +++ +++ LtCe++g+ppp+ W+kng++ ++++t k ++++++++L++ n +d G ++C A+N FUN_001238-T1 313 PPRFTKIPDELTLVTDGDALLTCEVTGSPPPSLFWLKNGNKVIPSETTKVTDYTGGTSLKLVNPDSKDGGIFQCFAEN 390 89***999999988888899*********************66656665699*************************9 PP == domain 5 score: 1.7 bits; conditional E-value: 0.38 Ig_3 18 svtLtCeaegnppp.titWykngkelss 44 +++L+C + +p+ tW + + s FUN_001238-T1 719 PINLRCAV-ESPTSiLLTWESPIS---S 742 789*****.777777999998777...3 PP == domain 6 score: -1.6 bits; conditional E-value: 4.1 Ig_3 28 nppptitWykngk 40 +++ ++tW k+ + FUN_001238-T1 831 HNSIEVTWEKPTE 843 3333666776666 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 4.6e-08 6.2e-05 1 82 [. 27 113 .. 27 122 .. 0.76 2 ! 47.8 0.0 1.2e-15 1.6e-12 2 87 .. 128 212 .. 127 215 .. 0.89 3 ! 38.0 0.0 1.3e-12 1.8e-09 2 78 .. 227 298 .. 226 310 .. 0.87 4 ! 51.3 0.0 9.4e-17 1.3e-13 1 88 [. 314 401 .. 314 403 .. 0.96 5 ? -2.5 0.0 5.8 7.8e+03 18 51 .. 720 753 .. 718 767 .. 0.82 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 4.6e-08 I-set 1 pkftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselkeskrvkvkaee.....gtatLtIsnvkkeDeGkYtckatnsagea 82 p+f +++d++++ +e + l+c v G+ ++ W+kdg+++ ++++v+ k ++ L I+++k+ G+Y+c a+ +ag+ FUN_001238-T1 27 PYFIHEPSDTVLRRNEPVALNCFVGGSsASNNIVWKKDGRPIDTNEDVRRKIAPngtllFNKILDIKDAKPY-VGEYQCFASSRAGRI 113 7899**********************945679**********997776666665114444455555555553.7*********99974 PP == domain 2 score: 47.8 bits; conditional E-value: 1.2e-15 I-set 2 kftqklkdvevkeGesaeleckvsGe.pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsag.eaeasae 87 kf +++++++ G+ a+++c+++ + p+ +++W k+g l++++rv + ++ L I++ +k+DeG+Y+c+a+n + + ++sa+ FUN_001238-T1 128 KFLYEPQNTTTWIGSVAQFSCQIRNAlPPATIEWRKNGMLLSSNERVLIFDRG---VLQIKETTKSDEGEYSCTARNVVHaRLSQSAS 212 68889******************9887999**********************9...*********************95404455555 PP == domain 3 score: 38.0 bits; conditional E-value: 1.3e-12 I-set 2 kftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatns 78 kf ++++v+v +G++ l+c ++G+p+p+v+W+k + + ++ + g + L++ nv+++D G+++c+a+ FUN_001238-T1 227 KFLGTPHNVTVVQGDETVLDCAATGDPTPSVTWKKLTGNPR-----VFDTSPGISNLEFVNVTENDGGEFKCQASSG 298 79999****************************98744444.....5788889*********************865 PP == domain 4 score: 51.3 bits; conditional E-value: 9.4e-17 I-set 1 pkftqklkdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeL 88 p+ft+ ++++++ ++ +a l+c+v+G+p+p+ Wlk+g+++ +s+ kv+ g ++L++ n +++D G+++c a+n++g+ ++ a + FUN_001238-T1 314 PRFTKIPDELTLVTDGDALLTCEVTGSPPPSLFWLKNGNKVIPSETTKVTDYTGGTSLKLVNPDSKDGGIFQCFAENQLGNIQTIAAV 401 89******************************************************************************99988876 PP == domain 5 score: -2.5 bits; conditional E-value: 5.8 I-set 18 aeleckvsGepepevsWlkdgselkeskrvkvka 51 ++l c v+ + +W + s+ + ++ + vk+ FUN_001238-T1 720 INLRCAVESPTSILLTWESPISSAHRTSYYTVKY 753 6899999999999999999877777777777776 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.0023 3.1 3 71 .. 36 107 .. 34 116 .. 0.68 2 ! 28.9 0.1 1.1e-09 1.5e-06 1 73 [. 134 202 .. 134 207 .. 0.91 3 ! 29.3 0.1 8.2e-10 1.1e-06 2 71 .. 234 296 .. 233 299 .. 0.89 4 ! 39.4 0.0 5.7e-13 7.7e-10 9 78 .. 329 396 .. 322 397 .. 0.93 5 ? 0.6 0.0 0.73 9.9e+02 11 41 .. 720 754 .. 713 771 .. 0.76 6 ? 5.7 0.1 0.02 26 7 46 .. 802 844 .. 800 860 .. 0.84 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0023 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslk....vkedngrttqssllisnvteedaGtYtCvvn 71 +++++ e + L+C++ +s ++ W+k+g ++++++ + ++ + ++ l i ++++ G+Y C ++ FUN_001238-T1 36 TVLRRNEPVALNCFVGGSSASNNIVWKKDGRPIDTNEDvrrkIAPNGTLLFNKILDIKDAKP-YVGEYQCFAS 107 6788999*********99999********999999988333333333333333333333333.5566666665 PP == domain 2 score: 28.9 bits; conditional E-value: 1.1e-09 ig 1 ptvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqs.sllisnvteedaGtYtCvvnnp 73 +++t+++G+ a+++C ++++ p++++ W+k+g+ + ++++ +++ l+i +t++d+G+Y+C+++n FUN_001238-T1 134 QNTTTWIGSVAQFSCQIRNALPPATIEWRKNGMLLSSNER-----VLIFDRgVLQIKETTKSDEGEYSCTARNV 202 58999******************************99999.....66666579******************996 PP == domain 3 score: 29.3 bits; conditional E-value: 8.2e-10 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvn 71 +vtv +G+ +L C a+ g+p p+vtW+k + +++ + ++ ++s+l ++nvte+d+G++ C+++ FUN_001238-T1 234 NVTVVQGDETVLDCAAT-GDPTPSVTWKK-LTGNPRVFD-----TSPGISNLEFVNVTENDGGEFKCQAS 296 78999************.*********87.455666666.....799*********************98 PP == domain 4 score: 39.4 bits; conditional E-value: 5.7e-13 ig 9 esatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsat 78 + a LtC+++ gsp+p+++W k+g+ i s++ ++ +++t+++sl ++n +d+G + C ++n +g+ + FUN_001238-T1 329 GDALLTCEVT-GSPPPSLFWLKNGNKVIPSET-TKVTDYTGGTSLKLVNPDSKDGGIFQCFAENQLGNIQ 396 5678******.*********************.*******************************999876 PP == domain 5 score: 0.6 bits; conditional E-value: 0.73 ig 11 atLtCsasegspgpdvtWskegktkieslk.....v 41 ++L+C ++ +++ + +tW+ ++ +++++ + FUN_001238-T1 720 INLRCAVE-SPTSILLTWESPISSAHRTSYytvkyH 754 79******.*********999888888877555543 PP == domain 6 score: 5.7 bits; conditional E-value: 0.02 ig 7 eGesatLtCsas...egspgpdvtWskegktkieslkvkedng 46 e+++a++ Cs+s ++sp+ +v ++ e +ie +++k++++ FUN_001238-T1 802 EHSTAQIYCSISlpgPSSPPRNVNFKYESHNSIEVTWEKPTET 844 789*******************************999444333 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.0 4.7e-07 0.00064 5 79 .] 32 122 .. 28 122 .. 0.79 2 ! 32.8 0.0 6.4e-11 8.6e-08 6 67 .. 133 203 .. 128 215 .. 0.80 3 ! 25.8 0.0 9.8e-09 1.3e-05 8 72 .. 234 303 .. 229 310 .. 0.76 4 ! 22.1 0.0 1.3e-07 0.00018 7 69 .. 322 394 .. 313 403 .. 0.72 5 ? -1.3 0.0 2.9 3.8e+03 30 78 .. 540 598 .. 537 599 .. 0.59 6 ? -2.3 0.0 5.8 7.8e+03 16 34 .. 719 737 .. 718 764 .. 0.74 7 ? 0.1 0.2 1 1.4e+03 13 55 .. 802 863 .. 793 865 .. 0.53 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 4.7e-07 Ig_2 5 tasptvvtegesvtLtCsasgnpp.akytwykdgkvlsssqn..........fftsnvs.....aedsGtYtCtarntkggkvsnpveitv 79 ++s+tv++++e+v L+C + g + ++ w kdg+++ ++ + ++ +++ G Y+C a+ +g s++v++ v FUN_001238-T1 32 EPSDTVLRRNEPVALNCFVGGSSAsNNIVWKKDGRPIDTNEDvrrkiapngtLLFNKILdikdaKPYVGEYQCFASSRAGRIASRKVRLDV 122 6888**************997666578***********77776666666676444553334466888999***999999999999998876 PP == domain 2 score: 32.8 bits; conditional E-value: 6.4e-11 Ig_2 6 asptvvtegesvtLtCsas.gnppakytwykdgkvlsssqn........fftsnvsaedsGtYtCtarntk 67 ++ t++++g+ +++C++ ppa++ w+k+g+ lss+ + + +++ + +d G Y+Ctarn FUN_001238-T1 133 PQNTTTWIGSVAQFSCQIRnALPPATIEWRKNGMLLSSNERvlifdrgvLQIKETTKSDEGEYSCTARNVV 203 445899***********9945788***************997755555444688**************944 PP == domain 3 score: 25.8 bits; conditional E-value: 9.8e-09 Ig_2 8 ptvvtegesvtLtCsasgnppakytwykdg...kvlsssqnfft....snvsaedsGtYtCtarntkggkvs 72 +v +g++ L C a g+p++++tw k +v+ +s+ ++ nv+++d+G ++C+a+ +g++ s FUN_001238-T1 234 NVTVVQGDETVLDCAATGDPTPSVTWKKLTgnpRVFDTSPG-ISnlefVNVTENDGGEFKCQASS-GGITIS 303 46799*********************964433488889999.43222356*************97.445444 PP == domain 4 score: 22.1 bits; conditional E-value: 1.3e-07 Ig_2 7 sptvvtegesvtLtCsasgnppakytwykdg.kvlsssqn.........fft.snvsaedsGtYtCtarntkgg 69 + t vt+g+ LtC++ g pp+++ w k+g kv++s + ++ n+ + d+G+++C a+n+ g+ FUN_001238-T1 322 ELTLVTDGDA-LLTCEVTGSPPPSLFWLKNGnKVIPSETTkvtdytggtSLKlVNPDSKDGGIFQCFAENQLGN 394 4466778877.9*****************99666663333355555554332355779**********997654 PP == domain 5 score: -1.3 bits; conditional E-value: 2.9 Ig_2 30 kytwykdgkvls..ssqn....fftsnvs.aedsGtYt...Ctarntkggkvsnpveit 78 ++ w+++g+ + s+++ f++++++ + + tY C + +++gk s+pv+ FUN_001238-T1 540 SIEWRQEGRRGWqaSTTEvpghFLHKTINgLAMGKTYIikvCAGTAKGWGKWSQPVTAR 598 56777777666633333366666667777444444465222555777789999998865 PP == domain 6 score: -2.3 bits; conditional E-value: 5.8 Ig_2 16 svtLtCsasgnpp.akytwy 34 +++L+C + + p+ + +tw FUN_001238-T1 719 PINLRCAVES-PTsILLTWE 737 6899999988.555667775 PP == domain 7 score: 0.1 bits; conditional E-value: 1 Ig_2 13 egesvtLtCsas....gnpp..akytwykdg.......kvlsssqn........fftsnvsaed 55 e ++ ++ Cs+s + pp +++++ + k++++ n +ft+n s+ d FUN_001238-T1 802 EHSTAQIYCSISlpgpSSPPrnVNFKYESHNsievtweKPTET--NgqlisyeiYFTNNSSLPD 863 6677788899888888566623333333333453222222222..1224445567777766655 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.0 0.0012 1.6 5 50 .. 33 76 .. 30 88 .. 0.76 2 ! 16.5 0.1 6.6e-06 0.0089 6 71 .. 134 211 .. 129 213 .. 0.86 3 ! 8.2 0.1 0.0026 3.5 11 80 .. 239 295 .. 230 301 .. 0.61 4 ! 14.4 0.0 3e-05 0.041 16 83 .. 330 391 .. 318 395 .. 0.68 5 ? 1.8 0.0 0.26 3.4e+02 59 88 .. 788 820 .. 785 821 .. 0.73 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0012 C2-set_2 5 psaslleaeekevvatCvsaggkPapritWlldgkeleaaetsseq 50 ps++ l+++ + v+++C++ g+ +i W +dg+++ + ++ +++ FUN_001238-T1 33 PSDTVLRRN-EPVALNCFVGGSSASNNIVWKKDGRPI-DTNEDVRR 76 566556665.67888*********************8.55555444 PP == domain 2 score: 16.5 bits; conditional E-value: 6.6e-06 C2-set_2 6 saslleaeekevvatCvsaggkPapritWlldgkel.............eaaetsseqdpesglvtvtselklvpsred 71 + ++++ + + + C +++ P+++i W ++g+ l ++++++++d+ + +t ++++s+++ FUN_001238-T1 134 Q-NTTTWIGSVAQFSCQIRNALPPATIEWRKNGMLLssnervlifdrgvLQIKETTKSDEGEYSCTARNVVHARLSQSA 211 3.33444469999***********************9999999999999999999999999999999999999988765 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0026 C2-set_2 11 eaeekevvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredngqsltCev 80 + + e v++C +a g P+p++tW + ++ + d+ +g +s+l++v e +g ++ C++ FUN_001238-T1 239 Q--GDETVLDC-AATGDPTPSVTWKKLTGNP------RVFDTSPG----ISNLEFVNVTENDGGEFKCQA 295 3..569999**.99**********7644443......23333333....244455555555555555555 PP == domain 4 score: 14.4 bits; conditional E-value: 3e-05 C2-set_2 16 evvatCvsaggkPapritWlldgkeleaaetsseqdpesglvtvtselklvpsredngqsltCevsye 83 +tC ++g+ +p++ Wl++g+++ +et++ +d + lklv + +g + C ++++ FUN_001238-T1 330 DALLTCEVTGSP-PPSLFWLKNGNKVIPSETTKVTDYTG-----GTSLKLVNPDSKDGGIFQCFAENQ 391 567899877766.5************6666665555333.....333566655577777888877765 PP == domain 5 score: 1.8 bits; conditional E-value: 0.26 C2-set_2 59 vtselklvpsr...edngqsltCevsyealres 88 v+s +k ++sr e++ ++++C++s ++++ + FUN_001238-T1 788 VQSHYKTKTSRfqsEHSTAQIYCSISLPGPSSP 820 66666666665333777889********99875 PP >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.018 25 9 55 .. 419 470 .. 413 491 .. 0.77 2 ! 22.6 0.0 1.3e-07 0.00018 6 90 .. 510 593 .. 507 598 .. 0.78 3 ? 6.4 0.0 0.014 19 56 82 .. 658 684 .. 634 698 .. 0.81 4 ! 8.6 0.3 0.003 4 3 79 .. 721 789 .. 717 804 .. 0.61 5 ! 9.0 0.0 0.0023 3 3 82 .. 823 904 .. 821 916 .. 0.72 6 ? -0.8 0.1 2.5 3.4e+03 3 51 .. 925 975 .. 923 1022 .. 0.72 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.018 Pur_ac_phosph_N 9 tg.pstsmtvsWrtp...e.attspvvqygtsssalsstatatsstyttedl 55 + +s+s+++sW +p + + ++ vv+y+ ++++++++ + ++++ ++l FUN_001238-T1 419 VAlSSSSIVLSWSPPtpgNfTIQGYVVHYQRQGGSEKQEILDNKTHFEFKNL 470 45579**********6663355888*********999998888887776654 PP == domain 2 score: 22.6 bits; conditional E-value: 1.3e-07 Pur_ac_phosph_N 6 lsltg.pstsmtvsWrtpe..attspvvqygtsssalsst.atatsstyttedltsgyihsatltgLepgttYyYrvgdens.gwsevys 90 +++t+ +++s+ + W++p+ ++++ +++y+ + +++ ++ ++a++++ +g+ + t++gL+ g tY +v++++ gw ++ + FUN_001238-T1 510 VNVTSlTPDSLDLAWQPPPklSQNGVIIKYSIEWRQEGRRgWQASTTE------VPGHFLHKTINGLAMGKTYIIKVCAGTAkGWGKWSQ 593 5677778**********9634667779999999988755415555544......59************************8887766655 PP == domain 3 score: 6.4 bits; conditional E-value: 0.014 Pur_ac_phosph_N 56 tsgyihsatltgLepgttYyYrvgden 82 + ++ +++ltgL pg +Y +v + + FUN_001238-T1 658 IEKHHKEYLLTGLRPGAEYLIKVMAWD 684 56788899***************8874 PP == domain 4 score: 8.6 bits; conditional E-value: 0.003 Pur_ac_phosph_N 3 qvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedltsgyihsatltgLepgttYyYrvg 79 +++ ++ + +ts+ ++W +p + +++ +y t + +l+++ + ++t + + s l+gL Y v+ FUN_001238-T1 721 NLRCAVES-PTSILLTWESPIS-SAHRTSYYTVKYHLKRSPNPRQKTL------TVETKSIILNGLRSERVYDIFVQ 789 44555555.***********87.4444444444445555555555554......34556666666666666665555 PP == domain 5 score: 9.0 bits; conditional E-value: 0.0023 Pur_ac_phosph_N 3 qvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedl....tsgyihsatltgLepgttYyYrvgden 82 +v+ + + ++s+ v+W p++t+++ ++y +++ss ++++s ++ ++ + +l +L+ +t +y+++++en FUN_001238-T1 823 NVNFKYES-HNSIEVTWEKPTETNGQLISYEIYFTNNSSLPDSEWS-FRPVRTgfigNRNEKMYRRLLQLKLDTPFYFKIRAEN 904 55555666.9********************9998776666555544.4444335665444444446778999999999998887 PP == domain 6 score: -0.8 bits; conditional E-value: 2.5 Pur_ac_phosph_N 3 qvhlsltg.pstsmtvsWrtpe.attspvvqygtsssalsstatatsstyt 51 +v++s+t ++ + +sW p+ ++++v +++ +++++ ++++++ + FUN_001238-T1 925 RVNVSYTIiSPKLVQLSWACPNnFNSAAVKRFTILITNNKNDPEGSWEKLS 975 688888888899999999999735555555666666666666666666554 PP >> FN3_DSCAM-DSCAML_C DSCAM/DSCAML C-terminal Fn3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.15 2.1e+02 5 67 .. 425 485 .. 421 501 .. 0.71 2 ! 11.1 0.0 0.00041 0.56 19 69 .. 535 587 .. 530 598 .. 0.85 3 ! 8.1 0.0 0.0036 4.8 23 66 .. 639 684 .. 617 704 .. 0.69 4 ! 10.4 0.1 0.0007 0.94 20 81 .. 746 807 .. 729 815 .. 0.87 5 ? -2.6 0.0 7.7 1e+04 48 69 .. 886 907 .. 863 909 .. 0.79 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.15 FN3_DSCAM-DSCAML_C 5 svtlnLsaWkdggCpilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhne 67 s+ l+ s + g+ i+ +vv+y+++g +e + + + +++++ +++L Y++ v+A+ + FUN_001238-T1 425 SIVLSWSPPTPGNFTIQGYVVHYQRQGGSEKQEILD--NKTHFEFKNLYGFINYTFFVRAYGD 485 555555555667789***********9988777644..4566777888888888888888765 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00041 FN3_DSCAM-DSCAML_C 19 pilsfvveyrkkgeeewilvsnnkeqe..klviedLkpatwYelkvtAhneaG 69 i ++++e+r++g++ w+ +++ + + + +i++L+ ++ Y +kv A G FUN_001238-T1 535 VIIKYSIEWRQEGRRGWQASTTEVPGHflHKTINGLAMGKTYIIKVCAGTAKG 587 5889***************9988776533678**************9988777 PP == domain 3 score: 8.1 bits; conditional E-value: 0.0036 FN3_DSCAM-DSCAML_C 23 fvveyrkkgeeewilvs..nnkeqeklviedLkpatwYelkvtAhn 66 +++ y + +++e + +k+++++++++L+p+ Y +kv A FUN_001238-T1 639 YRLFYVRLKSSETEQGPliIEKHHKEYLLTGLRPGAEYLIKVMAWD 684 55555444444433332113567899*****************975 PP == domain 4 score: 10.4 bits; conditional E-value: 0.0007 FN3_DSCAM-DSCAML_C 20 ilsfvveyrkkgeeewilvsnnkeqeklviedLkpatwYelkvtAhneaGsteaeyefaTlt 81 ++++v+y+ k++ + + + + e++++++++L+++ Y++ v++h + +++ + e +T + FUN_001238-T1 746 TSYYTVKYHLKRSPNPRQKTLTVETKSIILNGLRSERVYDIFVQSHYKTKTSRFQSEHSTAQ 807 579***************999*************************9988888888777765 PP == domain 5 score: -2.6 bits; conditional E-value: 7.7 FN3_DSCAM-DSCAML_C 48 viedLkpatwYelkvtAhneaG 69 + +Lk t + +k++A+ne G FUN_001238-T1 886 RLLQLKLDTPFYFKIRAENEKG 907 477889999999*******998 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 9.8 1.3e+04 6 36 .. 36 64 .. 32 67 .. 0.74 2 ! 10.5 0.0 0.00057 0.77 72 103 .. 179 210 .. 133 216 .. 0.83 3 ! 7.7 0.1 0.0041 5.5 2 39 .. 231 265 .. 230 272 .. 0.88 4 ? 4.5 0.0 0.042 56 73 108 .. 276 310 .. 267 311 .. 0.81 5 ! 9.0 0.0 0.0017 2.2 3 51 .. 320 367 .. 318 396 .. 0.81 6 ? -2.2 0.1 5 6.7e+03 24 48 .. 829 851 .. 823 869 .. 0.65 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 9.8 V-set 6 vtvaeGesvtLtCslssseseasqsvyWyrq 36 + ++e v L+C + s +as+ + W ++ FUN_001238-T1 36 TVLRRNEPVALNCFVGGS--SASNNIVWKKD 64 5566789999***88776..68888888775 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00057 V-set 72 dfsltiqnltlsDsGtYtCavipkgevvfgkg 103 ++ l+i++ t sD+G Y C +++ + + +++ FUN_001238-T1 179 RGVLQIKETTKSDEGEYSCTARNVVHARLSQS 210 799****************9766555555555 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0041 V-set 2 sprevtvaeGesvtLtCslssseseasqsvyWyrqppg 39 +p+ vtv++G L+C + ++ sv+W + + + FUN_001238-T1 231 TPHNVTVVQGDETVLDCAATGD---PTPSVTWKKLTGN 265 799**************88888...*******998765 PP == domain 4 score: 4.5 bits; conditional E-value: 0.042 V-set 73 fsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 l++ n+t++D G + C+ ++g +k ++L V FUN_001238-T1 276 SNLEFVNVTENDGGEFKCQ-ASSGGITISKIVWLIV 310 579999*************.7777777888887776 PP == domain 5 score: 9.0 bits; conditional E-value: 0.0017 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgk..epteliayysn 51 p e+t ++ ++++LtC+++ s + s+ W + ++ ++t++++ y+ FUN_001238-T1 320 PDELTLVTDGDALLTCEVTGS---PPPSLFWLKNGNKVipSETTKVTDYTG 367 7899*****************...*********988767766766666665 PP == domain 6 score: -2.2 bits; conditional E-value: 5 V-set 24 eseasqsvyWyrqppgkepteliay 48 es++s +v+W + ++ + +li y FUN_001238-T1 829 ESHNSIEVTWEKPTET--NGQLISY 851 4678999999998877..4444443 PP >> fn3_4 Fibronectin-III type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2.7 3.7e+03 8 40 .. 417 445 .. 409 459 .. 0.61 2 ? 0.9 0.0 0.44 6e+02 2 29 .. 715 742 .. 714 767 .. 0.72 3 ! 9.9 0.0 0.00069 0.93 14 101 .. 829 914 .. 817 916 .. 0.77 4 ! 15.0 0.2 1.9e-05 0.025 12 89 .. 931 1005 .. 919 1018 .. 0.76 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2.7 fn3_4 8 lkiakvevptgivlsWnvekldpkaaevesYel 40 +++a + ++ivlsW + p +++ Y + FUN_001238-T1 417 VAVAL--SSSSIVLSWSPP--TPGNFTIQGYVV 445 44444..889999999866..444445555555 PP == domain 2 score: 0.9 bits; conditional E-value: 0.44 fn3_4 2 pPqkp.elkiakvevptgivlsWnvekld 29 pP++p +l+ a e+pt+i l+W+ + ++ FUN_001238-T1 715 PPPRPiNLRCAV-ESPTSILLTWESPISS 742 677773677766.9*********977333 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00069 fn3_4 14 evptgivlsWnvekldpkaaevesYelflyqeetktssstdsWk..kigdvkAlpLpmactlsqfkegkkyyfavrakDiygRvGpfskv 101 e++++i ++W+ + ++ ++ sYe++ +++++ s+ s + ++g + m l q+k ++ yf +ra g +Gpf+k FUN_001238-T1 829 ESHNSIEVTWEKP--TETNGQLISYEIYFTNNSSLPDSE-WSFRpvRTGFIGNRNEKMYRRLLQLKLDTPFYFKIRAENEKG-YGPFCKT 914 5588999999755..88999**********774443333.2233336799***************************98866.9***985 PP == domain 4 score: 15.0 bits; conditional E-value: 1.9e-05 fn3_4 12 kvevptgivlsWnvekldpkaaevesYelflyqeetktssstdsWkkigdvkAlpLpmactlsqfkegkkyyfa.vrak 89 ++ +p+ + lsW + + + a+v+ + + +++++++ + sW k++ v + +ma+t + ++ ++f+ vra FUN_001238-T1 931 TIISPKLVQLSWACP-NNFNSAAVKRFTILITNNKNDPE---GSWEKLSFVPSKKCSMAVTKTIAVSQYEVHFMkVRAE 1005 357889999*****9.89999***********7644444...46*****************988887777777536665 PP >> Unc5_NetrinR_N Netrin receptor unc-5 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 1.2e-05 0.017 6 103 .. 26 118 .. 22 120 .. 0.74 2 ? -1.2 0.0 2.6 3.5e+03 8 34 .. 128 154 .. 123 174 .. 0.80 3 ? 1.5 0.0 0.37 4.9e+02 8 31 .. 227 250 .. 221 256 .. 0.90 4 ? 1.3 0.0 0.42 5.7e+02 6 51 .. 313 360 .. 310 375 .. 0.75 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 1.2e-05 Unc5_NetrinR_N 6 lPifleePedayivknkpvtLkCka...akalqiyFkCngewveeeehveeesvdeetgvrvvevsievtreqveelfgkeeykCeCvAwsskgt 97 P f++eP+d+ + +n+pv L+C + + + +i +k +g+ ++++e v+++ + ++ + + ++++ + + ++g+ y +C A s++g+ FUN_001238-T1 26 PPYFIHEPSDTVLRRNEPVALNCFVggsSASNNIVWKKDGRPIDTNEDVRRKIAP-NGTLLF-NKILDIK--DAKPYVGE--Y--QCFASSRAGR 112 59*********************7533267899***********99997776554.333333.4445554..34566664..5..5678888888 PP Unc5_NetrinR_N 98 vksrka 103 + srk+ FUN_001238-T1 113 IASRKV 118 888876 PP == domain 2 score: -1.2 bits; conditional E-value: 2.6 Unc5_NetrinR_N 8 ifleePedayivknkpvtLkCkaakal 34 +fl eP+++ + ++++C+ ++al FUN_001238-T1 128 KFLYEPQNTTTWIGSVAQFSCQIRNAL 154 799*****9999999999999988885 PP == domain 3 score: 1.5 bits; conditional E-value: 0.37 Unc5_NetrinR_N 8 ifleePedayivknkpvtLkCkaa 31 +fl P+++ +v++ +L C a+ FUN_001238-T1 227 KFLGTPHNVTVVQGDETVLDCAAT 250 79*******************996 PP == domain 4 score: 1.3 bits; conditional E-value: 0.42 Unc5_NetrinR_N 6 lPifleePedayivknkpvtLkCkaaka..lqiyFkCngewveeeehv 51 P+f + P++ +v + + L+C ++ + +++ ng++v +e++ FUN_001238-T1 313 PPRFTKIPDELTLVTDGDALLTCEVTGSppPSLFWLKNGNKVIPSETT 360 69*********************9975421567777777777666654 PP >> Fn3_VIN3 VIN3-like, fibronectin type-III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 1.6e-07 0.00021 8 80 .. 619 687 .. 615 690 .. 0.84 2 ? -1.2 0.0 2.4 3.3e+03 17 51 .. 838 874 .. 829 907 .. 0.56 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 1.6e-07 Fn3_VIN3 8 atsltviLgsedssssssekivgYkLwhrkakdeeypaeptctllapntrfvisgLePateYvfkvvsfnetr 80 at l+v+L +e ++ Y+L++ + k e + p ++ + +++++++gL+P +eY++kv++++++r FUN_001238-T1 619 ATALQVRLLPPRY---GKELVKEYRLFYVRLKSSETEQGP-LIIEKHHKEYLLTGLRPGAEYLIKVMAWDGQR 687 6777777755543...36899***********88877766.5789999********************99876 PP == domain 2 score: -1.2 bits; conditional E-value: 2.4 Fn3_VIN3 17 sedssssssekivgYkLwhrkak...deeypaeptctl 51 e+++ +++ ++++Y++++ +++ d e + +p++t FUN_001238-T1 838 WEKPT-ETNGQLISYEIYFTNNSslpDSEWSFRPVRTG 874 45554.46778888888887654223555555555554 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.046 61 18 81 .. 145 203 .. 139 207 .. 0.77 2 ? 5.4 0.0 0.019 25 9 40 .. 235 265 .. 229 277 .. 0.87 3 ! 7.9 0.0 0.0032 4.2 12 54 .. 326 367 .. 322 396 .. 0.77 4 ? -0.5 0.0 1.3 1.7e+03 56 78 .. 791 813 .. 783 816 .. 0.88 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.046 C2-set_3 18 rlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpl 81 + C+ P +++Wr++ g l s++e + ++g+ +++ + +s ++++sC+ rn + FUN_001238-T1 145 QFSCQIRNALPPATIEWRKN-GMLL-SSNERVLIFDRGVLQIKETT---KSDEGEYSCTARNVV 203 6789999999*******975.6455.55555666668999999875...577899999999975 PP == domain 2 score: 5.4 bits; conditional E-value: 0.019 C2-set_3 9 vegyedggirlvCrsaGWyPePqvqWrdekge 40 v + + ++ l C ++G P P+v W++ +g+ FUN_001238-T1 235 VTVVQGDETVLDCAATGD-PTPSVTWKKLTGN 265 6678899999****9995.********99986 PP == domain 3 score: 7.9 bits; conditional E-value: 0.0032 C2-set_3 12 yedggirlvCrsaGWyPePqvqWrdekgeklpslseklsqded 54 dg+ l+C+++G P P+ W ++ +++ps+++k++ + FUN_001238-T1 326 VTDGDALLTCEVTGS-PPPSLFWLKNGNKVIPSETTKVTDYTG 367 5789999******95.99********99999999987765544 PP == domain 4 score: -0.5 bits; conditional E-value: 1.3 C2-set_3 56 lfevetslvvressnknvsCsir 78 ++++ts +e+s++++ Csi+ FUN_001238-T1 791 HYKTKTSRFQSEHSTAQIYCSIS 813 58899999999**********96 PP >> Interfer-bind Interferon-alpha/beta receptor, fibronectin type III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.029 39 43 91 .. 442 489 .. 411 499 .. 0.84 2 ? -0.4 0.0 1.4 1.9e+03 38 84 .. 535 582 .. 506 595 .. 0.71 3 ? 5.4 0.0 0.023 31 3 84 .. 607 682 .. 605 692 .. 0.72 4 ? 6.3 0.8 0.012 16 42 90 .. 747 798 .. 726 810 .. 0.74 5 ? -2.7 0.0 7.5 1e+04 12 52 .. 829 859 .. 819 866 .. 0.55 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.029 Interfer-bind 43 qYkvsywknssnkekkelestnelvvlsdLepnteYCvsVqaesrkdnk 91 Y v y++++ + ek+e+ ++++ +++++L +Y + V+a+ + + FUN_001238-T1 442 GYVVHYQRQGGS-EKQEILDNKTHFEFKNLYGFINYTFFVRAYGDLLGR 489 5999*******9.999999999999***************995554444 PP == domain 2 score: -0.4 bits; conditional E-value: 1.4 Interfer-bind 38 lyqslqYkvsywknssn...kekkelestnelvvlsdLepnteYCvsVqa 84 ++ ++Y+++ ++++++ + ++e+ + + +++ L +++Y ++V a FUN_001238-T1 535 VI--IKYSIEWRQEGRRgwqASTTEVPGHFLHKTINGLAMGKTYIIKVCA 582 43..48999988888777777888999999999999********999977 PP == domain 3 score: 5.4 bits; conditional E-value: 0.023 Interfer-bind 3 lgpPevel.evedkslnvtvkdpetlkegknlslrelyqslqYkvsywknssn...kekkelestnelvvlsdLepnteYCvsVqa 84 ++ P++ + ++ ++l+v++ +p+ ++l + y+ ++y + +s+ + +e+ ++ + l+ L+p+ eY ++V a FUN_001238-T1 607 ISAPSLWIgHQNATALQVRLLPPR-----YGKELVKEYR-----LFYVRLKSSeteQGPLIIEKHHKEYLLTGLRPGAEYLIKVMA 682 677888888888899999999998.....3444555555.....44444333311246667999999*************999987 PP == domain 4 score: 6.3 bits; conditional E-value: 0.012 Interfer-bind 42 lqYkvsywknssn.kekkelestnelvvlsdLepnteYCvsVqa..esrkdn 90 Y+v y ++s ++k+l+ ++++++l+ L+ ++ Y + Vq + ++++ FUN_001238-T1 747 SYYTVKYHLKRSPnPRQKTLTVETKSIILNGLRSERVYDIFVQShyKTKTSR 798 568888777776667778888888888*****************43222222 PP == domain 5 score: -2.7 bits; conditional E-value: 7.5 Interfer-bind 12 vedkslnvtvkdpetlkegknlslrelyqslqYkvsywkns 52 ++ +s++vt + p+ ++ q ++Y++++++ns FUN_001238-T1 829 ESHNSIEVTWEKPT----------ETNGQLISYEIYFTNNS 859 55666666666665..........11112235666666666 PP >> Ig_RIMBP2 RIMBP2-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.0 0.0024 3.2 2 83 .. 409 482 .. 408 500 .. 0.74 2 ? 0.8 0.5 0.51 6.9e+02 5 29 .. 506 529 .. 501 542 .. 0.72 3 ? 2.4 0.0 0.17 2.2e+02 5 35 .. 716 747 .. 713 798 .. 0.83 4 ! 9.8 0.0 0.0008 1.1 1 47 [. 816 855 .. 816 860 .. 0.79 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0024 Ig_RIMBP2 2 lPdpPldvqveagpqdgtllvsWlpvtidasgtsngaavtGYavyadgkkvaevdsptadhvlvelsklelsleprevtVrT 83 +P pP+++ v +++++++sW p+t + +++GY+v + + +e ++ +++ e ++l + ++ Vr+ FUN_001238-T1 409 QPGPPTNL-VAVALSSSSIVLSWSPPTP------GNFTIQGYVVHYQRQGGSEKQEILDNKTHFEFKNLY-GFINYTFFVRA 482 68999997.55556778888*******4......346899***999888777777777777777777775.66666666665 PP == domain 2 score: 0.8 bits; conditional E-value: 0.51 Ig_RIMBP2 5 pPldvqveagpqdgtllvsWlpvti 29 pP+ v+v+ ++ +l + W+p+ FUN_001238-T1 506 PPEIVNVTS-LTPDSLDLAWQPPPK 529 777788876.8999*******9863 PP == domain 3 score: 2.4 bits; conditional E-value: 0.17 Ig_RIMBP2 5 pPldvqveagpq.dgtllvsWlpvtidasgts 35 pP+ +++++ ++ + ++l++W+ + +a+ ts FUN_001238-T1 716 PPRPINLRCAVEsPTSILLTWESPISSAHRTS 747 7777777766543899******9998877766 PP == domain 4 score: 9.8 bits; conditional E-value: 0.0008 Ig_RIMBP2 1 glPdpPldvqveagpqdgtllvsWlpvtidasgtsngaavtGYavya 47 g+ +pP++v+ + + +++++ v+W+++t +ng ++++Y +y FUN_001238-T1 816 GPSSPPRNVNFKYE-SHNSIEVTWEKPTE-----TNG-QLISYEIYF 855 6779******9985.679**********4.....444.667888886 PP >> Ig_Rha78A_N Rha78A-like, N-terminal immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.1 0.26 3.5e+02 32 98 .. 533 596 .. 511 599 .. 0.71 2 ? 1.6 0.0 0.35 4.7e+02 65 88 .. 664 687 .. 656 698 .. 0.84 3 ? 1.1 0.1 0.51 6.8e+02 56 101 .. 726 770 .. 723 773 .. 0.83 4 ? 3.0 0.0 0.12 1.6e+02 46 102 .. 818 874 .. 788 877 .. 0.74 5 ! 7.7 0.0 0.0044 5.9 20 102 .. 938 1023 .. 929 1026 .. 0.82 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.26 Ig_Rha78A_N 32 gvrqtayqievasseeadvwdsgkvessesvlvpypgkpLksrtryywrVrvwdedgeasawsepas 98 + +y ie ++++ + w+ + e ++l + + + L+ +++y ++V + +++g + +ws+p + FUN_001238-T1 533 NGVIIKYSIEWRQEG-RRGWQASTTEVPGHFLHK-TINGLAMGKTYIIKVCAGTAKG-WGKWSQPVT 596 555556777777664.566666666666655443.45679999**********9999.8****9987 PP == domain 2 score: 1.6 bits; conditional E-value: 0.35 Ig_Rha78A_N 65 pypgkpLksrtryywrVrvwdedg 88 +y + L+++ +y ++V +wd + FUN_001238-T1 664 EYLLTGLRPGAEYLIKVMAWDGQR 687 6777889**************875 PP == domain 3 score: 1.1 bits; conditional E-value: 0.51 Ig_Rha78A_N 56 vessesvlvpypgkpLksrtryywrVrvwdedgeasawsepasfet 101 ves s+l +++ + +++++ y++V+ + ++ + + ++ ++et FUN_001238-T1 726 VESPTSILLTWESPISSAHRTSYYTVKYHLKRS-PNPRQKTLTVET 770 89**********999999999999**9998886.467777777776 PP == domain 4 score: 3.0 bits; conditional E-value: 0.12 Ig_Rha78A_N 46 eeadvwdsgkvessesvlvpypgkpLksrtryywrVrvwdedg.easawsepasfetg 102 ++ + k es +s+ v+++ ++ + ++ +++++ ++++ s+ws ++tg FUN_001238-T1 818 SSPPRNVNFKYESHNSIEVTWEKPTETNGQLISYEIYFTNNSSlPDSEWS-FRPVRTG 874 44555678899*************************99999998668888.5555555 PP == domain 5 score: 7.7 bits; conditional E-value: 0.0044 Ig_Rha78A_N 20 PrlsWklesdergvrqtayqievass..eeadvw.dsgkvessesvlvpypgkpLksrtryywrVrvwdedgeasawsepasfetg 102 +lsW +++ + ++ + + i+++++ + + +w + v s++ + + + ++ + +++Vr+ ++++ +ws++ ++tg FUN_001238-T1 938 VQLSWACPNNFNSAAVKRFTILITNNknDPEGSWeKLSFVPSKKCSMAVTKTIAVSQYEVHFMKVRAEYGEKTPGKWSNIIEISTG 1023 689**********************954335667444556666666666667999999**********************999998 PP >> Fn3_R-PTP-O R-PTP-O-like, fibronectin type III domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 5.1e-05 0.069 4 60 .. 425 482 .. 422 497 .. 0.87 2 ? -2.8 0.1 8.1 1.1e+04 5 13 .. 520 528 .. 517 538 .. 0.79 3 ? 0.4 0.0 0.81 1.1e+03 4 31 .. 937 966 .. 934 971 .. 0.80 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 5.1e-05 Fn3_R-PTP-O 4 llelrWlPPkpPt.aydgFniyierdgnstetatvdenthefvtelkepgkyrvsvtt 60 ++l+W PP p + +g+ ++ +r+g s + d++th + +l + +y++ v++ FUN_001238-T1 425 SIVLSWSPPTPGNfTIQGYVVHYQRQGGSEKQEILDNKTHFEFKNLYGFINYTFFVRA 482 689******99763789***********************999999999999988875 PP == domain 2 score: -2.8 bits; conditional E-value: 8.1 Fn3_R-PTP-O 5 lelrWlPPk 13 l l W PP FUN_001238-T1 520 LDLAWQPPP 528 889****96 PP == domain 3 score: 0.4 bits; conditional E-value: 0.81 Fn3_R-PTP-O 4 llelrWlPPkp..PtaydgFniyierdgns 31 l++l+W P+ +a+ F+i i++++n FUN_001238-T1 937 LVQLSWACPNNfnSAAVKRFTILITNNKND 966 689****99863367899******999986 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.0043 5.8 14 33 .. 241 260 .. 233 265 .. 0.85 2 ? 2.6 0.0 0.13 1.8e+02 13 33 .. 328 348 .. 317 368 .. 0.86 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0043 Ig_PDGFR_d4 14 geqtvtCvaeGmPqPeveWf 33 e ++ C a+G P+P+v+W FUN_001238-T1 241 DETVLDCAATGDPTPSVTWK 260 566789*************5 PP == domain 2 score: 2.6 bits; conditional E-value: 0.13 Ig_PDGFR_d4 13 sgeqtvtCvaeGmPqPeveWf 33 +g+ +tC +G P P++ W+ FUN_001238-T1 328 DGDALLTCEVTGSPPPSLFWL 348 677889**************7 PP >> SusE SusE outer membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 5.3 7.1e+03 27 55 .. 418 446 .. 406 462 .. 0.65 2 ? -2.4 0.0 5.7 7.7e+03 29 59 .. 514 546 .. 509 559 .. 0.76 3 ? -1.0 0.0 2.1 2.8e+03 22 56 .. 719 753 .. 705 773 .. 0.77 4 ? 5.0 0.0 0.028 37 24 59 .. 823 858 .. 798 867 .. 0.82 5 ? -0.1 0.0 1 1.4e+03 32 61 .. 935 965 .. 921 988 .. 0.81 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 5.3 SusE 27 lenasneavtfsWeaadygvnaavsYtvq 55 + + s+ ++++sW+ + g + Y v FUN_001238-T1 418 AVALSSSSIVLSWSPPTPGNFTIQGYVVH 446 33357788899999886555455555555 PP == domain 2 score: -2.4 bits; conditional E-value: 5.7 SusE 29 nasneavtfsWeaa.dygvna.avsYtvqfdkk 59 + + +++ + W+ + ++ n+ ++Y ++ + FUN_001238-T1 514 SLTPDSLDLAWQPPpKLSQNGvIIKYSIEWRQE 546 567889999***999995555378998886655 PP == domain 3 score: -1.0 bits; conditional E-value: 2.1 SusE 22 nlvLnlenasneavtfsWeaadygvnaavsYtvqf 56 + L + +s +++ ++We++ Ytv FUN_001238-T1 719 PINLRCAVESPTSILLTWESPISSAHRTSYYTVKY 753 677778888999999*****988888888999875 PP == domain 4 score: 5.0 bits; conditional E-value: 0.028 SusE 24 vLnlenasneavtfsWeaadygvnaavsYtvqfdkk 59 +n++++s ++++++We++ +sY++ f ++ FUN_001238-T1 823 NVNFKYESHNSIEVTWEKPTETNGQLISYEIYFTNN 858 567888899**********8778889*****99775 PP == domain 5 score: -0.1 bits; conditional E-value: 1 SusE 32 neavtfsWeaa.dygvnaavsYtvqfdkkgk 61 + v++sW + +++ a+ +t+ + ++ + FUN_001238-T1 935 PKLVQLSWACPnNFNSAAVKRFTILITNNKN 965 56799******999*****99**99988844 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 613 (0.0239969); expected 510.9 (0.02) Passed bias filter: 533 (0.0208651); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 19 [number of targets reported over threshold] # CPU time: 0.47u 0.38s 00:00:00.85 Elapsed: 00:00:00.43 # Mc/sec: 11503.44 // Query: FUN_001239-T1 [L=330] Description: FUN_001239 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-25 89.0 22.1 2.4e-24 86.7 22.1 1.9 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.1e-05 25.8 4.8 1.1e-05 25.8 4.8 2.2 3 7tm_4 Olfactory receptor 5.9e-05 23.1 15.8 0.00011 22.2 15.8 1.7 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.14 12.7 0.4 0.33 11.5 0.4 1.5 1 CCT CCT motif Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 86.7 22.1 3.7e-28 2.4e-24 1 260 [] 19 267 .. 19 267 .. 0.78 Alignments for each domain: == domain 1 score: 86.7 bits; conditional E-value: 3.7e-28 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfal.vyallegdwvfgevl..CklvtaldvvnltasillltaisiDRYlaIvkplky 93 gN+ +i++++ +++lrt tn fl++LavaD+ v+++++p+ +a + + ++ l +++ ++++asi++l+ + +DRYla+vkpl+y FUN_001239-T1 19 GNGAIITLVSSKRQLRTKTNAFLTSLAVADFFVGVFTVPLLHfCTATNTCKNSLHPKLpeLTWFNITRWIFSYASIVNLCSLVLDRYLAVVKPLRY 114 8**********************************9999754133333344444444411567889999*************************** PP xxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlall.lslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkek 188 +++t+rr++++i ++Wv+a++ lslp + + +++ + +++ +++t+++ +++ + p+++ ++c +++ ++k++++e+ FUN_001239-T1 115 LSFMTRRRVICMISLAWVIAVApLSLPIASLVSSNPV----------FMM--------KIFTVIVAIFFEFFPCVLQVFCVGSMVCIAFKHKRSER 192 ********************98355555555544332..........333........35677777777777***********************9 PP xxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 189 skkkksarker.....kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 +k+ + ++r + ++t+ v +v ++ + y il+ +++++ + +++ + ++i + ++ns+lNP+ Y FUN_001239-T1 193 ALEKQLRYNHRvvfktQDINTVKVTAFVAGCALASYSILIRCSVIVFYDSTKDCGDFNYKIPV--LVLNSALNPLTY 267 944433333334554466779999999999999999999999999555666666666666655..579******998 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.8 4.8 1.8e-09 1.1e-05 3 134 .. 12 147 .. 10 160 .. 0.75 2 ? -0.4 1.0 0.17 1.1e+03 55 121 .. 152 215 .. 132 248 .. 0.51 3 ? -2.7 0.1 0.85 5.4e+03 251 274 .. 256 279 .. 251 282 .. 0.81 Alignments for each domain: == domain 1 score: 25.8 bits; conditional E-value: 1.8e-09 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllql..ffihkfsllesa..vllamavdrfv 94 l + ++++Gn+ i+ ++ +++ l fl+ la++d + + t+P + ++ + s++ l +l f i + + ++ l + +dr+ FUN_001239-T1 12 LCF-LAIIGNGAIITLVSSKRQLRTKTNAFLTSLAVADFFVGVFTVPLLHFCTATNTCKNSLHPKLPELtwFNITRWIFSYASivNLCSLVLDRYL 106 444.5789***************************************988888888888888888866521556655444433115678899**** PP 7tm_4 95 aiysplryteiltnkvisriglvvlvrsvi.lvlplifllr 134 a+++plry + +t +++ + +v +v+ l lp+ l+ FUN_001239-T1 107 AVVKPLRYLSFMTRRRVICMISLAWVIAVApLSLPIASLVS 147 ************99866544444444433315566666655 PP == domain 2 score: -0.4 bits; conditional E-value: 0.17 7tm_4 55 flvdareisfeacllqlf.fihkfsllesavllamavdrf.vaiysplryteiltnkvisriglvvlvr 121 f+++ + a +++ f + +++ + s v++a + r a+ ++lry + v++++ + +v+ FUN_001239-T1 152 FMMKIFTVIV-AIFFEFFpCVLQVFCVGSMVCIAFKHKRSeRALEKQLRYNHR----VVFKTQDINTVK 215 4444433332.222222212344445677777777777752467777777642....233333333333 PP == domain 3 score: -2.7 bits; conditional E-value: 0.85 7tm_4 251 llfPPvlnPivysvktkeirdavv 274 l++ lnP+ y++ +i+++++ FUN_001239-T1 256 LVLNSALNPLTYALLKSDIKKVLK 279 567788999999999999988765 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 15.8 1.7e-08 0.00011 1 177 [. 13 191 .. 13 282 .. 0.76 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 1.7e-08 7TM_GPCR_Srsx 1 lvvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltgtqlkre......eCFlliivyvfgltaqsvllLvigiDlliav 90 +++ +iGN +i l+ k++Lr+k++ ++ +++ad ++ v++++ + + ++ k + e +++i ++ a+ v l ++++D+ +av FUN_001239-T1 13 CFLAIIGNGAIITLVSSKRQLRTKTNAFLTSLAVADFFVGVFTVPLLHFCTATNTCKNSlhpklpELTWFNITRWIFSYASIVNLCSLVLDRYLAV 108 5799***********************************999988766555444333322222336779999999********************* PP 7TM_GPCR_Srsx 91 kfPirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek 177 P+rY ++ +++ +++++ + + +++ l l + +++ ++ + +++ + +f+++ +++ v++v ++ i +k+k+++ FUN_001239-T1 109 VKPLRYLSFMTRRRVICMISLAWVIAVAPLSLPIASLVSSNPVFMMKIFTV--IVAIFFEFFPCVL--QVFCVGSMVCIAFKHKRSE 191 ************977777777777777777666666555544444444444..4455555555444..4566777777777777665 PP >> CCT CCT motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.4 5.2e-05 0.33 8 26 .. 185 203 .. 183 206 .. 0.94 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 5.2e-05 CCT 8 YreKrkeRkfekkirYevR 26 ++ Kr+eR ek+ rY+ R FUN_001239-T1 185 FKHKRSERALEKQLRYNHR 203 89***************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (330 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1317 (0.0515561); expected 510.9 (0.02) Passed bias filter: 638 (0.0249755); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.36s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3177.62 // Query: FUN_001240-T1 [L=148] Description: FUN_001240 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-41 142.8 3.0 1.2e-41 142.5 3.0 1.0 1 TMEM72 Transmembrane protein family 72 3.4e-05 24.6 3.7 4.9e-05 24.1 3.4 1.5 1 Cg6151-P Uncharacterized conserved protein CG6151-P 0.00071 20.5 0.4 1.1 10.3 0.3 2.1 2 SPW SPW repeat domain ------ inclusion threshold ------ 0.21 12.1 0.9 17 6.0 0.2 2.1 2 Phage_holin_3_6 Putative Actinobacterial Holin-X, holin supe Domain annotation for each model (and alignments): >> TMEM72 Transmembrane protein family 72 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 142.5 3.0 1.8e-45 1.2e-41 4 134 .. 9 135 .. 6 136 .. 0.97 Alignments for each domain: == domain 1 score: 142.5 bits; conditional E-value: 1.8e-45 TMEM72 4 klwnklelvtRllGvaTaivllgvGvelllkgekelavyllisgilvsllEisyvvallldvclrceeeslkfelWeavlrldafkksllYvvlsv 99 ++ ++++ +tR++G++T+++l++ Gv ++ +++k++a yl+i g++v++ Ei++ +l++c++c e+s++++lW+ +l++d++kksllY+ lsv FUN_001240-T1 9 FIIRHFTSITRIFGLFTSAALWWTGVYMTDNEDKRIAAYLMICGVAVTFFEIAF----ILNKCACCSEDSFAHTLWKYLLAIDNWKKSLLYASLSV 100 6889**************************************************....9************************************* PP TMEM72 100 vlflhpvlvwlvtvaGtmLvilgllylilsfrkkk 134 v++lhp ++w++ +aG++L +++llyli++fr + FUN_001240-T1 101 VCYLHPDEYWQALIAGVLLDVTALLYLIRTFRTRN 135 *******************************9876 PP >> Cg6151-P Uncharacterized conserved protein CG6151-P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 3.4 7.7e-09 4.9e-05 28 110 .. 45 131 .. 18 134 .. 0.80 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 7.7e-09 Cg6151-P 28 silalvsgfvvlfiEvPlllricpts..ekfdefiek....fetnwmraalYlvmavvqwlslivqatslivaavlllitavlYglaal 110 +++ +++g+ v+f+E+ ++l+ c + f++ k + nw + +lY+ ++vv +l + + ++a vll +ta+lY++ + FUN_001240-T1 45 AAYLMICGVAVTFFEIAFILNKCACCseDSFAHTLWKyllaI-DNWKKSLLYASLSVVCYLHPD-EYWQALIAGVLLDVTALLYLIRTF 131 678899*************99886541134544443311105.9***************99998.99999999***********98765 PP >> SPW SPW repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.3 0.00017 1.1 6 48 .. 18 65 .. 14 89 .. 0.76 2 ! 8.5 0.0 0.00062 4 13 50 .. 94 131 .. 92 141 .. 0.81 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00017 SPW 6 nlllGlwlalspwvlg.fss....taaawnavvvGlavallallalve 48 + ++Gl+ ++ w++g + + ++ a +++G+av+++ ++ +++ FUN_001240-T1 18 TRIFGLFTSAALWWTGvYMTdnedKRIAAYLMICGVAVTFFEIAFILN 65 5689************4333467788888899*******999877665 PP == domain 2 score: 8.5 bits; conditional E-value: 0.00062 SPW 13 lalspwvlgfsstaaawnavvvGlavallallalvepa 50 l +s v+ + +++ w+a+++G+++ ++all l+++ FUN_001240-T1 94 LYASLSVVCYLHPDEYWQALIAGVLLDVTALLYLIRTF 131 56777777777899****************99998843 PP >> Phage_holin_3_6 Putative Actinobacterial Holin-X, holin superfamily III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.2 0.0027 17 41 85 .. 16 60 .. 1 80 [. 0.78 2 ? 4.7 2.1 0.0065 42 59 93 .. 63 133 .. 44 144 .. 0.55 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0027 Phage_holin_3_6 41 aaagvlallgllfllvalalalaevlplwlaalivaavllvvaav 85 ++ +++l++ ++l ++ ++ ++ ++ +a+l++++v + + FUN_001240-T1 16 SITRIFGLFTSAALWWTGVYMTDNEDKRIAAYLMICGVAVTFFEI 60 566689999999999999999988878999999988777655444 PP == domain 2 score: 4.7 bits; conditional E-value: 0.0065 Phage_holin_3_6 59 a....................................lalaev..l.p.lwlaalivaavllvvaavlalvgrkr 93 + + v l p + ali +++l v a++ ++++ + FUN_001240-T1 63 IlnkcaccsedsfahtlwkyllaidnwkksllyaslsV----VcyLhPdEYWQALIAGVLLDVTALLYLIRTFRT 133 24444455555555555555544455555444322211....222234489999998888888888888777764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (148 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 965 (0.0377765); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.33s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 1526.21 // Query: FUN_001241-T1 [L=554] Description: FUN_001241 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-19 70.0 0.0 1.1e-18 68.2 0.0 1.8 1 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 4.9e-10 39.5 11.3 1.9e-08 34.4 7.2 2.5 2 LRR_8 Leucine rich repeat 1.6e-09 38.2 11.8 3.9e-06 27.4 2.1 2.7 2 LRR_4 Leucine Rich repeats (2 copies) 5.4e-09 35.7 5.9 3.5e-05 23.2 2.2 2.2 2 LRR_14 Leucine-rich repeat region 2e-06 27.3 14.2 0.073 13.7 0.3 5.2 4 LRR_1 Leucine Rich Repeat 4.9e-05 23.6 2.2 8.8e-05 22.8 2.2 1.4 1 LRR_LRWD1 Leucine-rich repeat and WD repeat-containing ------ inclusion threshold ------ 0.054 14.1 0.2 0.11 13.2 0.2 1.5 1 LRR_Zer-1 Zer-1-like, Leucine-rich repeats 0.28 11.3 3.1 0.81 9.8 2.6 1.9 2 LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain 0.9 9.9 5.5 1.8 8.9 1.7 2.7 4 LRR_R13L1-DRL21 R13L1/DRL21 LRRs Domain annotation for each model (and alignments): >> Exo_endo_phos Endonuclease/Exonuclease/phosphatase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.2 0.0 3.9e-22 1.1e-18 2 224 .] 187 525 .. 186 525 .. 0.82 Alignments for each domain: == domain 1 score: 68.2 bits; conditional E-value: 3.9e-22 xxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx........xxxxxxxxxxxxx RF Exo_endo_phos 2 twNvngg...........nadaardparldalaellraydpDvllLQEvdlddaealllalla..lggyysyvys........ggggggggGvail 76 +Nv+++ +++a+++++r+ a+++ + +y++D+l LQE+ ++ ++ l+ l + y +++ ++++ +G+ai+ FUN_001241-T1 187 CYNVLCDkyctrqiygycPSWALNWEYRKSAILKEILHYGADILSLQEIETEQFCNFFLPELQqhG--YDGIFSPksrartmtEEDRKYVDGCAIF 280 59999999999999999*******************************999996666666655431..222212245566777899********** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..................................xxxxxxxxxxxxxxxxxxxxxxxx RF Exo_endo_phos 77 srfpltsvivrtlsedgdpslrialapvggtlvvlvvl..................................pappapprlarreqrlllllllaa 138 +r + +++++ +l+e+++ +++ a + ++ ++v++ ++ + ++ q l+ +l + FUN_001241-T1 281 YRTSKFTFVKEYLIEFNQLAMANASGADDMLNRVMTKDnigiaallelkegyvsynndvnmprqqvlvsnvhIHWDPEFKDVKLIQTVMLMHELMN 376 **********************************99766666666666665555555555555555555555555555555555555555555555 PP xxxxxxxxxxx.................xxxxxxxxxxxxxxxxxxxxxxx.............................xx....xxxxxxxxxx RF Exo_endo_phos 139 llaarsgpvil.................aGDfNaapdsgdlrrllsrglll.............................sf....ggggtgfgtt 184 + ++ ++ + + +GD+N+ p+sg +l++++ ++ ++ +++++ ++ t FUN_001241-T1 377 IMQEINPGFMVqggkngtppsksiplvcCGDLNSLPNSGVVEFLEKGRVRSdhgdfldmkyegflsrlsngkngeksgdlTHcfklERAYSEEQMT 472 55555555555****************************************************999999988888776652277889********* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxx RF Exo_endo_phos 185 ptartpnggsrlDyilvsgglavrsvgvlidpgal.............tgSDH 224 +++ t +++ +Dyi+++++l v + + + ++ ++ +SDH FUN_001241-T1 473 YSNLTYSFTGVIDYIYFTSDLLVPVGVLGSVSQQYikenkiigwphphFPSDH 525 *******************99999999999999999***************** PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.4 7.2 6.8e-12 1.9e-08 3 61 .] 53 109 .. 52 109 .. 0.97 2 ! 15.9 2.4 4.1e-06 0.012 23 61 .] 95 132 .. 90 132 .. 0.94 Alignments for each domain: == domain 1 score: 34.4 bits; conditional E-value: 6.8e-12 LRR_8 3 LrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 L+ L L++N+lt+++++ + l +Lk+LdLs+N+l++l p + +L Lr+L L +N L FUN_001241-T1 53 LTALFLNDNNLTKIPPEISR-LAQLKHLDLSSNKLRSL-PSELGDLVTLRELLLCNNSL 109 899***************99.*****************.9****************987 PP == domain 2 score: 15.9 bits; conditional E-value: 4.1e-06 LRR_8 23 glsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 +l L++L L nN+l+ l p+ + L +L++L L+gN+L FUN_001241-T1 95 DLVTLRELLLCNNSLRAL-PNELGKLFQLQTLGLQGNPL 132 6889**************.9*****************97 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 2.1 1.4e-09 3.9e-06 3 40 .. 53 90 .. 52 94 .. 0.86 2 ! 15.2 2.4 9.9e-06 0.028 2 39 .. 98 136 .. 97 141 .. 0.91 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 1.4e-09 LRR_4 3 LetLdLsnNritdidp.lskLpnLetLdLsgNnkitdls 40 L+ L L++N++t+i+p +s L +L++LdLs+N k+++l+ FUN_001241-T1 53 LTALFLNDNNLTKIPPeISRLAQLKHLDLSSN-KLRSLP 90 7789************7666*********888.888873 PP == domain 2 score: 15.2 bits; conditional E-value: 9.9e-06 LRR_4 2 nLetLdLsnNritdidp.lskLpnLetLdLsgNnkitdl 39 L++L L nN++ +++ l+kL +L+tL L gN++ +d+ FUN_001241-T1 98 TLRELLLCNNSLRALPNeLGKLFQLQTLGLQGNPLPSDI 136 69***************9999************777887 PP >> LRR_14 Leucine-rich repeat region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 2.2 1.2e-08 3.5e-05 58 119 .. 39 102 .. 32 105 .. 0.80 2 ! 21.4 1.1 4.3e-08 0.00012 42 90 .. 92 137 .. 88 141 .. 0.91 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 1.2e-08 LRR_14 58 siseLPeeIgkLqfLqtLdlrgteikeLPssvvkLrkLmcLrvdegtr..lPdgignLtsLeeL 119 i++L + +L fL L l++++++++P+++ +L +L++L +++++ lP+ +g+L L+eL FUN_001241-T1 39 PIRNLSPTLWQLDFLTALFLNDNNLTKIPPEISRLAQLKHLDLSSNKLrsLPSELGDLVTLREL 102 5778888888899999999999999999999999999999988875444689999999999988 PP == domain 2 score: 21.4 bits; conditional E-value: 4.3e-08 LRR_14 42 hlgkLlhLRYLgLrntsiseLPeeIgkLqfLqtLdlrgteikeLPssvv 90 +lg+L+ LR L L+n s++ LP+e+gkL LqtL l+g + LPs + FUN_001241-T1 92 ELGDLVTLRELLLCNNSLRALPNELGKLFQLQTLGLQG---NPLPSDIL 137 79***********************************9...67788775 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.2 0.001 2.9 2 23 .] 53 73 .. 52 73 .. 0.87 2 ! 13.7 0.3 2.6e-05 0.073 1 23 [] 75 96 .. 75 96 .. 0.89 3 ! 7.5 0.8 0.003 8.5 2 23 .] 99 119 .. 98 119 .. 0.90 4 ? 3.4 0.1 0.074 2.1e+02 1 15 [. 121 135 .. 121 140 .. 0.77 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.001 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L+ L L++Nnl+ ++p+++++l FUN_001241-T1 53 LTALFLNDNNLT-KIPPEISRL 73 889********7.999999876 PP == domain 2 score: 13.7 bits; conditional E-value: 2.6e-05 LRR_1 1 nLeeLdLsnNnlsgllpeslgnl 23 +L++LdLs+N+l +lp++lg+l FUN_001241-T1 75 QLKHLDLSSNKLR-SLPSELGDL 96 59**********5.9**999876 PP == domain 3 score: 7.5 bits; conditional E-value: 0.003 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 L+eL L+nN+l lp++lg+l FUN_001241-T1 99 LRELLLCNNSLR-ALPNELGKL 119 9**********5.99*999987 PP == domain 4 score: 3.4 bits; conditional E-value: 0.074 LRR_1 1 nLeeLdLsnNnl.sgl 15 +L++L L++N+l s FUN_001241-T1 121 QLQTLGLQGNPLpS-D 135 59**********33.3 PP >> LRR_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, LRR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 2.2 3.1e-08 8.8e-05 35 98 .. 67 132 .. 47 151 .. 0.85 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 3.1e-08 LRR_LRWD1 35 pnllgrlkklkeldlsnnlletlpanlg.lshlrilrctnnqlgdv.ttlhqfpeleelslegnpf 98 p + rl +lk ldls n l +lp++lg l lr l nn l + l ++ +l+ l l+gnp+ FUN_001241-T1 67 PPEISRLAQLKHLDLSSNKLRSLPSELGdLVTLRELLLCNNSLRALpNELGKLFQLQTLGLQGNPL 132 45579**********************98899**98888888887736799**************7 PP >> LRR_Zer-1 Zer-1-like, Leucine-rich repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.2 3.7e-05 0.11 21 66 .. 40 86 .. 28 126 .. 0.81 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 3.7e-05 LRR_Zer-1 21 ledle.llsk.esLtsLiLydvkdleeaidticqlkkLrhLDisqsee 66 + +l+ +l++ + Lt+L L d ++l + ++i++l +L+hLD+s ++ FUN_001241-T1 40 IRNLSpTLWQlDFLTALFLND-NNLTKIPPEISRLAQLKHLDLSSNKL 86 556653455537799999977.6788899***************9875 PP >> LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 2.3 0.0038 11 64 111 .. 63 109 .. 32 112 .. 0.68 2 ? 9.8 2.6 0.00029 0.81 48 112 .. 73 133 .. 61 143 .. 0.80 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0038 LRR_NXF1-5 64 LdglsdivqkapnlkiLnLsknelkse.reLdkvkglkleeLwlegNpL 111 L ++ +++ ++lk L+Ls+n+l+s +eL + + l eL+l +N+L FUN_001241-T1 63 LTKIPPEISRLAQLKHLDLSSNKLRSLpSELGDL--VTLRELLLCNNSL 109 33344445677899**********9953677665..4556777777776 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00029 LRR_NXF1-5 48 ipeLlsLnlsnnklykL.dglsdivqkapnlkiLnLsknelkse.reLdkvkglkleeLwlegNpLc 112 + +L +L+ls+nkl +L +l d+v +l+ L L +n+l+ +eL k+ ++l+ L l+gNpL FUN_001241-T1 73 LAQLKHLDLSSNKLRSLpSELGDLV----TLRELLLCNNSLRALpNELGKL--FQLQTLGLQGNPLP 133 5678889999999888844677776....6999********9753788876..7889999*****96 PP >> LRR_R13L1-DRL21 R13L1/DRL21 LRRs # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.1 3e+03 108 125 .. 41 59 .. 27 61 .. 0.75 2 ? 8.9 1.7 0.00064 1.8 71 124 .. 53 104 .. 43 107 .. 0.86 3 ? 8.0 3.1 0.0012 3.5 68 125 .. 73 128 .. 58 130 .. 0.71 4 ? -2.0 0.0 1.6 4.4e+03 98 120 .. 399 421 .. 398 425 .. 0.86 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.1 LRR_R13L1-DRL21 108 esl.pslgqLpsLkeLeie 125 +l p+l+qL L+ L ++ FUN_001241-T1 41 RNLsPTLWQLDFLTALFLN 59 455488*******999775 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00064 LRR_R13L1-DRL21 71 LkeLkikgykGskfpswledsslsnLvsleLsncknleslps.lgqLpsLkeLei 124 L+ L +++ + +k+p + s l +L++l+Ls+ ++l slps lg+L +L+eL + FUN_001241-T1 53 LTALFLNDNNLTKIPPEI--SRLAQLKHLDLSS-NKLRSLPSeLGDLVTLRELLL 104 566777777778999999..99**********9.59*****99********9977 PP == domain 3 score: 8.0 bits; conditional E-value: 0.0012 LRR_R13L1-DRL21 68 hsnLkeLkikgykGskfpswledsslsnLvsleLsncknleslps.lgqLpsLkeLeie 125 +Lk+L +++ k +++ps l l +L++l L+n ++l lp+ lg+L +L++L ++ FUN_001241-T1 73 LAQLKHLDLSSNKLRSLPSEL--GDLVTLRELLLCN-NSLRALPNeLGKLFQLQTLGLQ 128 457777888888888888888..6777788888887.4778887778888888887765 PP == domain 4 score: -2.0 bits; conditional E-value: 1.6 LRR_R13L1-DRL21 98 sleLsncknleslpslgqLpsLk 120 s+ L c l+slp+ g ++ L+ FUN_001241-T1 399 SIPLVCCGDLNSLPNSGVVEFLE 421 678999********999888887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (554 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 446 (0.0174594); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5311.92 // Query: FUN_001242-T1 [L=228] Description: FUN_001242 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0098 16.2 0.3 5.6 7.3 0.0 2.6 2 DUF8124 Domain of unknown function (DUF8124) ------ inclusion threshold ------ 0.017 15.9 0.8 42 5.0 0.0 3.3 3 PmrD IraM/RssC family 0.062 12.8 0.0 0.22 10.9 0.0 1.7 1 Serpulina_VSP Serpulina hyodysenteriae variable surface prot 1.3 9.7 5.3 53 4.5 0.1 3.8 4 YHR052C-B YHR052C-B Domain annotation for each model (and alignments): >> DUF8124 Domain of unknown function (DUF8124) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.00088 5.6 50 87 .. 60 98 .. 50 100 .. 0.88 2 ! 6.4 0.1 0.0017 11 51 87 .. 148 185 .. 135 187 .. 0.84 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.00088 DUF8124 50 dreevlravaeeadaGetvtlG.tvtlrpdgtvvdaels 87 r++ l++ ++ +++G+ v++ ++tl+++gtv+ ++++ FUN_001242-T1 60 SRSRGLQTTTSANNVGQDVRMKeSLTLSANGTVIAHKVE 98 688899*************996379*********99876 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0017 DUF8124 51 reevlravaeeadaGetvtlG.tvtlrpdgtvvdaels 87 r + l++ ++ +++G+ v++ ++tl+++gtv+ ++++ FUN_001242-T1 148 RPKGLQTTTSANNVGQDVRMKeSLTLSANGTVIAHKVE 185 6678999999********996379*********99876 PP >> PmrD IraM/RssC family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.0097 62 40 64 .. 79 103 .. 58 105 .. 0.86 2 ? 5.0 0.0 0.0065 42 37 65 .. 120 148 .. 116 150 .. 0.93 3 ? 3.1 0.0 0.025 1.6e+02 42 65 .. 168 191 .. 162 194 .. 0.87 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.0097 PmrD 40 rpGdiLsptkkgvlvnnkertikil 64 r + L++ ++g+++ +k++++ki+ FUN_001242-T1 79 RMKESLTLSANGTVIAHKVENLKIY 103 55678999****************9 PP == domain 2 score: 5.0 bits; conditional E-value: 0.0065 PmrD 37 lfLrpGdiLsptkkgvlvnnkertikiln 65 +++r+ ++L++ ++g ++ ++++++ki++ FUN_001242-T1 120 YVVRKKETLTLSANGNVIAQNVENLKIYR 148 679999*********************96 PP == domain 3 score: 3.1 bits; conditional E-value: 0.025 PmrD 42 GdiLsptkkgvlvnnkertikiln 65 + L++ ++g+++ +k++++ki + FUN_001242-T1 168 KESLTLSANGTVIAHKVENLKICQ 191 5789999**************975 PP >> Serpulina_VSP Serpulina hyodysenteriae variable surface protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 3.5e-05 0.22 294 370 .. 113 189 .. 67 205 .. 0.85 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 3.5e-05 Serpulina_VSP 294 eayernpydlrilpslslsvnsdivsiiveaGlGyrvvdtGkkfnaananqgsklehsvrwsayGevyvrpvkdlew 370 + + y +r +l+ls+n ++++ ve yr + +a n+ q +++ s+ sa G v + v++l+ FUN_001242-T1 113 PGATHVGYVVRKKETLTLSANGNVIAQNVENLKIYRPKGLQTTTSANNVGQDVRMKESLTLSANGTVIAHKVENLKI 189 55667889999999************************9999999***********************999999875 PP >> YHR052C-B YHR052C-B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 0.6 3.8e+03 26 38 .. 62 74 .. 59 76 .. 0.80 2 ? 2.3 0.0 0.04 2.6e+02 4 17 .. 86 99 .. 80 101 .. 0.88 3 ? 4.5 0.1 0.0083 53 4 17 .. 130 143 .. 128 163 .. 0.66 4 ? 2.5 0.0 0.035 2.3e+02 4 17 .. 173 186 .. 167 192 .. 0.89 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.6 YHR052C-B 26 qrGvtattnaPav 38 rG tt a v FUN_001242-T1 62 SRGLQTTTSANNV 74 6999999999776 PP == domain 2 score: 2.3 bits; conditional E-value: 0.04 YHR052C-B 4 msananvvaakimn 17 +san v+a k+ n FUN_001242-T1 86 LSANGTVIAHKVEN 99 79*********976 PP == domain 3 score: 4.5 bits; conditional E-value: 0.0083 YHR052C-B 4 msananvvaakimn 17 +san nv+a + n FUN_001242-T1 130 LSANGNVIAQNVEN 143 79******987755 PP == domain 4 score: 2.5 bits; conditional E-value: 0.035 YHR052C-B 4 msananvvaakimn 17 +san v+a k+ n FUN_001242-T1 173 LSANGTVIAHKVEN 186 79*********976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (228 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 540 (0.0211392); expected 510.9 (0.02) Passed bias filter: 339 (0.0132707); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2250.07 // Query: FUN_001243-T1 [L=135] Description: FUN_001243 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 30K_MP_C_Ter C-Terminal of 30K viral movement proteins 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 BACOVA_N BACOVA_00430, N-terminal domain Domain annotation for each model (and alignments): >> 30K_MP_C_Ter C-Terminal of 30K viral movement proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 1.2e-05 0.15 119 140 .. 18 39 .. 5 58 .. 0.79 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.2e-05 30K_MP_C_Ter 119 lltmldtGsdkhyffakritpt 140 + m+dtG+++hyf ++ p+ FUN_001243-T1 18 VHDMMDTGTSQHYFVRAHVWPS 39 557***********99988886 PP >> BACOVA_N BACOVA_00430, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 2.6e-05 0.34 6 19 .. 9 22 .. 6 27 .. 0.91 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.6e-05 BACOVA_N 6 GRqWvEsGLvnDmi 19 GR++v+sG v Dm+ FUN_001243-T1 9 GRKYVDSGFVHDMM 22 9************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (135 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 676 (0.0264631); expected 510.9 (0.02) Passed bias filter: 348 (0.013623); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1359.77 // Query: FUN_001244-T1 [L=265] Description: FUN_001244 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-18 66.1 0.0 6.8e-18 65.3 0.0 1.4 1 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily 1.5e-05 26.1 0.1 2.7e-05 25.3 0.1 1.5 1 DIOX_N non-haem dioxygenase in morphine synthesis N-te Domain annotation for each model (and alignments): >> 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.3 0.0 5.3e-22 6.8e-18 5 101 .] 125 231 .. 121 231 .. 0.85 Alignments for each domain: == domain 1 score: 65.3 bits; conditional E-value: 5.3e-22 2OG-FeII_Oxy 5 lvlnyypphpdpel....tlglgphtdasiltillqddvgglqvlkd..gkwidvpplpgalvvniGdallllsngryksvlHrvl.pvnkgee.. 91 l+l +yp +++++ ++++g+htd++ +t+l+qd+ gl+vl ++i+ pplpga+vvn+ d ++ ++ +++ks++Hrv p+++ + FUN_001244-T1 125 LRLLHYPSIKEESDikpgQIRCGEHTDYGSITLLFQDEMPGLEVLPLgyEEYIPAPPLPGAVVVNVADLMQRWTADKLKSTRHRVSiPAEEF-Hrh 219 556667777776667777999***********************7553355***********************************555553.258 PP 2OG-FeII_Oxy 92 ..Risiafflrp 101 R s++ff++p FUN_001244-T1 220 vpRRSLVFFVHP 231 99*******997 PP >> DIOX_N non-haem dioxygenase in morphine synthesis N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.1 2.1e-09 2.7e-05 43 101 .. 3 64 .. 1 85 [. 0.86 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 2.1e-09 DIOX_N 43 idelleaakefFalPleeKeklaksp..sfrGygrlgkektdg.kkldwkeffdlgtelped 101 i+ ++e fF+l ++ K+k+a++ s G+ ++ +ek+++ + +d ke+f+++ + +e+ FUN_001244-T1 3 IASIFELGDYFFRLDDDIKQKYARPAsgSGHGWVAFEREKVSSdRPADRKEAFNITEPCNEQ 64 78899*****************99854599***********9999**********9995432 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (265 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 545 (0.0213349); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2693.40 // Query: FUN_001245-T1 [L=205] Description: FUN_001245 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-22 79.4 0.1 6.9e-22 78.8 0.1 1.2 1 DIOX_N non-haem dioxygenase in morphine synthesis N-termin ------ inclusion threshold ------ 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 DUF4516 Domain of unknown function (DUF4516) Domain annotation for each model (and alignments): >> DIOX_N non-haem dioxygenase in morphine synthesis N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.8 0.1 5.4e-26 6.9e-22 10 107 .. 12 111 .. 5 120 .. 0.86 Alignments for each domain: == domain 1 score: 78.8 bits; conditional E-value: 5.4e-26 DIOX_N 10 ssedreevlaklreAcrewGffqvvnhgvpeelidelleaakefFalPleeKeklaks.p.sfrGygrlgkektdg.kkldwkeffdlgtelpedd 102 sse+ ++++++l +A++++Gf++++nhg+p+e+id ++e+ fF+l +e Ke ++k+ + s G+ + +e+t++ + +d+ke+fd+g d+ FUN_001245-T1 12 SSEAVKALADQLYHAFSTIGFVYLKNHGIPQEMIDSVFETYDAFFNLNEEVKENYSKKvGtSPDGWDACERESTNPeRPGDLKESFDVGAIN--DE 105 458899*************************************************77744699*************99***********994..33 PP DIOX_N 103 p.agkp 107 + ++ + FUN_001245-T1 106 NfRWPD 111 324444 PP >> DUF4516 Domain of unknown function (DUF4516) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 1.2e-05 0.15 17 40 .. 135 158 .. 131 163 .. 0.87 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 1.2e-05 DUF4516 17 svlsmlaGaqvVHnyYKPdltipe 40 ++++m+ G q+VH P+ +i++ FUN_001245-T1 135 VLSCMAIGLQMVHRVLIPETEIKR 158 799***********9999998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (205 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 848 (0.0331963); expected 510.9 (0.02) Passed bias filter: 804 (0.0314739); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2027.04 // Query: FUN_001245-T2 [L=247] Description: FUN_001245 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-14 52.1 0.0 1.7e-13 51.2 0.0 1.3 1 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily 3e-07 31.6 0.1 4.9e-07 30.9 0.1 1.2 1 DIOX_N non-haem dioxygenase in morphine synthesis N-te Domain annotation for each model (and alignments): >> 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.2 0.0 1.3e-17 1.7e-13 5 79 .. 127 206 .. 124 207 .. 0.91 Alignments for each domain: == domain 1 score: 51.2 bits; conditional E-value: 1.3e-17 2OG-FeII_Oxy 5 lvlnyypphpdpel....tlglgphtdasiltillqddvgglqvlkd..gkwidvpplpgalvvniGdallllsngryksv 79 l+ nyyp +d + ++++g+htd++ +t+l+qddvggl+v + g++i+ p++g+++vni d ++ ++ +++ksv FUN_001245-T2 127 LRYNYYPVIKDITKvkpgQIRCGEHTDYGGITLLIQDDVGGLEV-TNvaGNFISATPMRGTVLVNIADLMQRWTADKLKSV 206 788999999888878888999***********************.455677***************************997 PP >> DIOX_N non-haem dioxygenase in morphine synthesis N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.1 3.8e-11 4.9e-07 43 106 .. 6 71 .. 4 80 .. 0.83 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 3.8e-11 DIOX_N 43 idelleaakefFalPleeKeklaks.p.sfrGygrlgkektdg.kkldwkeffdlgtelpeddp.agk 106 id ++e+ fF+l +e Ke ++k+ + s G+ + +e+t++ + +d+ke+fd+g d++ ++ FUN_001245-T2 6 IDSVFETYDAFFNLNEEVKENYSKKvGtSPDGWDACERESTNPeRPGDLKESFDVGAIN--DENfRWP 71 899*******************77744699*************99***********993..3322444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (247 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 625 (0.0244666); expected 510.9 (0.02) Passed bias filter: 556 (0.0217655); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2467.15 // Query: FUN_001245-T3 [L=227] Description: FUN_001245 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-22 79.0 0.1 9.3e-22 78.4 0.1 1.2 1 DIOX_N non-haem dioxygenase in morphine synthesis N-te 6.9e-06 26.8 0.0 1.3e-05 25.9 0.0 1.4 1 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily Domain annotation for each model (and alignments): >> DIOX_N non-haem dioxygenase in morphine synthesis N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.4 0.1 7.3e-26 9.3e-22 10 106 .. 12 110 .. 5 119 .. 0.86 Alignments for each domain: == domain 1 score: 78.4 bits; conditional E-value: 7.3e-26 DIOX_N 10 ssedreevlaklreAcrewGffqvvnhgvpeelidelleaakefFalPleeKeklaks.p.sfrGygrlgkektdg.kkldwkeffdlgtelpedd 102 sse+ ++++++l +A++++Gf++++nhg+p+e+id ++e+ fF+l +e Ke ++k+ + s G+ + +e+t++ + +d+ke+fd+g d+ FUN_001245-T3 12 SSEAVKALADQLYHAFSTIGFVYLKNHGIPQEMIDSVFETYDAFFNLNEEVKENYSKKvGtSPDGWDACERESTNPeRPGDLKESFDVGAIN--DE 105 458899*************************************************77744699*************99***********993..33 PP DIOX_N 103 p.agk 106 + ++ FUN_001245-T3 106 NfRWP 110 22444 PP >> 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 1e-09 1.3e-05 5 47 .. 166 211 .. 163 224 .. 0.84 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 1e-09 2OG-FeII_Oxy 5 lvlnyypphpdpel....tlglgphtdasiltillqddvgglqvlkd 47 l+ nyyp +d + ++++g+htd++ +t+l+qddvggl+v k+ FUN_001245-T3 166 LRYNYYPVIKDITKvkpgQIRCGEHTDYGGITLLIQDDVGGLEV-KR 211 788999999888878888999**********************9.44 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (227 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 632 (0.0247407); expected 510.9 (0.02) Passed bias filter: 591 (0.0231356); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2268.21 // Query: FUN_001246-T1 [L=320] Description: FUN_001246 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-20 74.8 0.1 1.9e-20 74.1 0.1 1.3 1 DIOX_N non-haem dioxygenase in morphine synthesis N-te 2.4e-19 70.0 0.0 6.6e-19 68.6 0.0 1.7 2 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily Domain annotation for each model (and alignments): >> DIOX_N non-haem dioxygenase in morphine synthesis N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.1 0.1 1.5e-24 1.9e-20 1 112 [. 7 124 .. 7 130 .. 0.85 Alignments for each domain: == domain 1 score: 74.1 bits; conditional E-value: 1.5e-24 DIOX_N 1 iPvidlsrl.........ss.edreevlaklreAcrewGffqvvnhgvpeelidelleaakefFalPleeKeklaksp..sfrGygrlgkektdg. 83 iP++d+s + ++ e+ + v++++ +A++++Gf+ ++nhg+p+e++d ++++ efF+l+ e K+k+ak++ G+ ++ ke+t++ FUN_001246-T1 7 IPIVDFSVMsvehkdplkENfEAVKIVADEVYQAFSTIGFVFLKNHGIPQETVDVVFKTYDEFFNLSSEVKAKYAKTKgtLTNGWDAVEKESTNPe 102 899999977887776655444667889***********************************************88864566*************9 PP DIOX_N 84 kkldwkeffdlgtelpeddpagkplrgpn 112 + +d+ke+fd+ + + +l +pn FUN_001246-T1 103 RPGDLKESFDVECLD---E----NLIWPN 124 9***********992...2....344444 PP >> 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 0.72 9.2e+03 57 75 .. 108 126 .. 100 135 .. 0.75 2 ! 68.6 0.0 5.2e-23 6.6e-19 5 99 .. 179 282 .. 175 284 .. 0.86 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 0.72 2OG-FeII_Oxy 57 pgalvvniGdallllsngr 75 ++++ v++ d l+++n FUN_001246-T1 108 KESFDVECLDENLIWPNQE 126 5788888888889999983 PP == domain 2 score: 68.6 bits; conditional E-value: 5.2e-23 2OG-FeII_Oxy 5 lvlnyypphpdpel....tlglgphtdasiltillqddvgglqvlkd.gkwidvpplpgalvvniGdallllsngryksvlHrvl.pvnkgee... 91 l+ nyyp +d + ++++g+htd++ +t+l+qd+++gl+v ++ g+++ p++g+++vni d l+ ++ +++ks+ Hrvl p + ++ FUN_001246-T1 179 LRYNYYPRIEDFGRvkpgQIRCGEHTDYGAITVLFQDENEGLEVKNKsGEFVAARPIKGTVLVNIADLLQRWTADKLKSTVHRVLiPESEAKRrip 274 78899999988888899999************************655577***********************************55555444666 PP 2OG-FeII_Oxy 92 Risiaffl 99 R s+++f FUN_001246-T1 275 RRSLVLFA 282 66777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (320 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 732 (0.0286553); expected 510.9 (0.02) Passed bias filter: 689 (0.026972); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3097.20 // Query: FUN_001247-T1 [L=101] Description: FUN_001247 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0066 17.6 22.3 0.0082 17.3 22.3 1.1 1 Toxin_TOLIP Snake toxin and toxin-like protein ------ inclusion threshold ------ 0.085 13.8 22.0 0.11 13.4 22.0 1.2 1 UPAR_LY6 u-PAR/Ly-6 domain Domain annotation for each model (and alignments): >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 22.3 6.4e-07 0.0082 1 72 [] 22 97 .. 22 97 .. 0.82 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 6.4e-07 Toxin_TOLIP 1 LkCytCeeeksnsnCl...ketkCsesekyCvttvtsa..kskklisksCsssCeessselgvasvsvsCCqtdlCN 72 L+Cy+C+e++s s+C+ k++ C++ + Cv + +++ s++ ++++Cs+ ++ + sCC++dlCN FUN_001247-T1 22 LTCYECSESSSWSQCTsrqKMKYCDSGWR-CVMVKEKSlgMSSYYYRRTCSEASVCDDFCKDKPDCVYSCCNSDLCN 97 89*************83334556877776.8888888889778999*****997766777777789**********9 PP >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 22.0 8.8e-06 0.11 2 80 .. 21 97 .. 20 99 .. 0.82 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 8.8e-06 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgdtqCvtttiklsgggkksslsvkgC..spscpelnetseigsltvtesccqsdlCn 80 +l+Cy+C + ss+s+c s + C ++ Cv ++ k g +s + ++ C ++ c + +++ +scc+sdlCn FUN_001247-T1 21 SLTCYECSESSSWSQCTSRQkmkYC-DSGWRCVMVKEKSL--GMSSYYYRRTCseASVCDDFCKDKPD----CVYSCCNSDLCN 97 79***************99989899.55588998888877..48999******666666666665555....5999*******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1311 (0.0513212); expected 510.9 (0.02) Passed bias filter: 406 (0.0158935); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1015.25 // Query: FUN_001248-T1 [L=185] Description: FUN_001248 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-05 24.5 0.7 3e-05 24.1 0.7 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.7 1.2e-09 3e-05 163 260 .] 4 139 .. 1 139 [. 0.87 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 1.2e-09 xxxxxxxxxxxxxxxxxxxxxxxxxxx..........................................xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 163 llpllvilvcyvrilrtlrksakkeks..........................................kkkksarkerkalktllvvvvvfvlcw 216 ++p++ + ++y+ri+ t+r++ + ++ +k++ ++ +++l++v+++f lcw FUN_001248-T1 4 VMPTVTMPFIYARIFFTVRRHVRLMALqttqleynseikedclakttsikipttsqdnnknickgspqyARKRRLPEHVLNITVLGTVIAFFELCW 99 56*********************998888999999999999999999999999999999999998886544444444446667999********** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 217 lPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 +++ ++ l + +++ al ++ +++++ns++NP+ Y FUN_001248-T1 100 SLDIVVSSCKKL----GLCVIDDSALRVSDVMIFANSAINPVGY 139 *99999999999....99***********************966 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 604 (0.0236445); expected 510.9 (0.02) Passed bias filter: 468 (0.0183206); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1895.77 // Query: FUN_001249-T1 [L=348] Description: FUN_001249 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-68 231.8 22.1 2e-68 231.6 22.1 1.0 1 wnt wnt family Domain annotation for each model (and alignments): >> wnt wnt family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 231.6 22.1 8e-73 2e-68 2 306 .. 40 347 .. 39 348 .] 0.89 Alignments for each domain: == domain 1 score: 231.6 bits; conditional E-value: 8e-73 wnt 2 lkglskkqrelckrepevmesvaegaklaieeCqkqfrnerWnCstleeksvfgkvlkkgtretafvyaissagvahavtracsegeleeCscdkk 97 ++gls+ qr+lc++ p + +++++g++++++eC+++f +rWnC+ l eks+f++ +t+e+af++a+ sa++a++v+ ac++ +++eCsc++ FUN_001249-T1 40 ARGLSDGQRKLCRKVPGLQTAIKKGIEKGLSECEREFMWNRWNCTLLGEKSFFQR-APDNTQEAAFTTALLSAALAYNVALACTKKDVTECSCEEV 134 6799****************************************99988866655.56679*********************************** PP wnt 98 krekkeeeeewewggCsdnieyglkfskefvdarekkkkkdaralmnlhnneaGrkavkksmkteckChGvsgscsvktcwkklpefrevgkaLke 193 kr+ +e+++w+w+gCs n+ +g +++ +f+ + ++ ++++++++n+hn ++G +++k++ ++c + + k c +lp+++++++ +k+ FUN_001249-T1 135 KRRPFREQSTWKWKGCSVNVGFGSSIAGRFMLSYRS--NNTQSSIINKHNVRVGLEVLKENRVVKCT---MGKRGNAKACRLTLPPLHKISRLIKS 225 9999988999*********************99998..788999****************9998885...5666789******************* PP wnt 194 kydkavkv..kkkkkkrk.klvkkkkka......kkptkkdLvylekSpdyCekdeklgslGtkgReCnktskgsdgCellCCgrGyntekeevee 280 ky+ka+kv k++k++ + ++++++ k+p k++Lv+l++Sp+yC ++ k + Gt+gR+C++++ +d+C+l+CCgrGyn++ ++++ FUN_001249-T1 226 KYNKATKVvaI-KRRKKQsLFLRTNERHlyernfKRPMKSELVFLSHSPSYCYRQDKYRIPGTRGRKCRRNTLREDDCSLMCCGRGYNRNVLHKKR 320 *******8431.3333333223333333455555************************************************************** PP wnt 281 rCkCkfk.wCCevkCkkCeekkevhtc 306 C+C+ + +Ck C++ + ++tc FUN_001249-T1 321 FCSCSNAaEDGHCQCKVCTDVVIENTC 347 ****9873567899********99999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (348 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 872 (0.0341358); expected 510.9 (0.02) Passed bias filter: 377 (0.0147583); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 3508.41 // Query: FUN_001250-T1 [L=203] Description: FUN_001250 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.2 9.7 7.4 2.4 8.7 0.1 3.9 3 TRAF6_Z2 TNF receptor-associated factor 6 zinc finger 2 Domain annotation for each model (and alignments): >> TRAF6_Z2 TNF receptor-associated factor 6 zinc finger 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.2 0.04 1e+03 6 13 .. 56 63 .. 55 64 .. 0.85 2 ? 8.7 0.1 9.6e-05 2.4 4 13 .. 104 113 .. 103 114 .. 0.90 3 ? 1.8 0.3 0.014 3.6e+02 14 27 .] 129 142 .. 117 142 .. 0.86 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.04 TRAF6_Z2 6 CpQCqrpF 13 C+ Cq F FUN_001250-T1 56 CLRCQKGF 63 *****877 PP == domain 2 score: 8.7 bits; conditional E-value: 9.6e-05 TRAF6_Z2 4 vnCpQCqrpF 13 vnC QC +F FUN_001250-T1 104 VNCAQCEETF 113 9*****9998 PP == domain 3 score: 1.8 bits; conditional E-value: 0.014 TRAF6_Z2 14 qKcqlniHilkeCP 27 qK +H l+ CP FUN_001250-T1 129 QKTGSGVHCLTSCP 142 7777889******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1134 (0.0443922); expected 510.9 (0.02) Passed bias filter: 332 (0.0129967); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1998.28 // Query: FUN_001251-T1 [L=375] Description: FUN_001251 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-10 40.7 60.0 0.00031 21.4 19.9 3.4 3 Furin-like_2 Furin-like repeat, cysteine-rich ------ inclusion threshold ------ 2 9.5 0.0 2 9.5 0.0 8.9 10 Antistasin Antistasin family Domain annotation for each model (and alignments): >> Furin-like_2 Furin-like repeat, cysteine-rich # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 17.7 2.1e-07 0.0027 3 95 .. 57 162 .. 55 172 .. 0.81 2 ! 13.0 11.0 9.8e-06 0.12 33 97 .. 150 225 .. 143 229 .. 0.71 3 ! 21.4 19.9 2.4e-08 0.00031 3 97 .. 245 340 .. 240 345 .. 0.81 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 2.1e-07 Furin-like_2 3 gcalcseengcltckkrlfllleregirqigvclkscpsgy.fgvrgqevnkctk....ckaeecescfskd..fcikckekfylhk....g..kc 85 gc++c++ c +c+ ++ + + ++i c +scp+g+ + r+++ c++ c+a +c +c ++ c++c +++y + g +c FUN_001251-T1 57 GCEKCTDGLICQKCRSSFIPVEYERNKKKIVRCTRSCPMGFnMTSRTPHSTLCVRthfpCRARNCIKCHPQNptSCLNCSRGYYSLQksitGnvRC 152 8*************9987777667778999**********9446689999999866666**********987447*********86422332448* PP Furin-like_2 86 lstcpeglaa 95 +++cp +++ FUN_001251-T1 153 VRHCPIDYTP 162 ****999876 PP == domain 2 score: 13.0 bits; conditional E-value: 9.8e-06 Furin-like_2 33 gvclkscpsgyfg.vrgqevnkctk....ck..aeecescfskdfcikckekfylhkgk....clstcpeglaaen 97 c+++cp y vr+ c+ c +++c +cf c kc+++f+ + k c+++cp++l+a n FUN_001251-T1 150 VRCVRHCPIDYTPtVRTDGQRFCKDpnseCLsvVPNCAKCFDSVRCRKCRSDFHAFFNKsqmvCVRNCPNNLVAFN 225 57*********8615655555566422224322579*****************98865544559999999887755 PP == domain 3 score: 21.4 bits; conditional E-value: 2.4e-08 Furin-like_2 3 gcalcseengcltckkrlfllleregirqigvclkscpsgyfgvrgqevnkctkckaeecescfskdfcikckekfylhk.g...kclstcpegla 94 ca+c ++ c +ck+r + l r +c++scp g+f +g+ ++ + + +ce+c + c+kc +f ++ g c ++cp+g++ FUN_001251-T1 245 KCARCPDKINCRRCKPRHYKL--RTSSSANFTCVSSCPLGFFK-KGRRCQRLAEGCIANCEQCTNGYDCVKCNPEFSRFQrGvhiSCARKCPSGYV 337 79***************9987..556667789**********6.56666666666666******************98862344469999999988 PP Furin-like_2 95 aen 97 +++ FUN_001251-T1 338 SQE 340 765 PP >> Antistasin Antistasin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.7 0.91 1.2e+04 20 24 .. 57 61 .. 56 62 .. 0.83 2 ? 8.2 0.1 0.00041 5.2 5 15 .. 88 98 .. 84 101 .. 0.85 3 ? -4.3 4.0 2 2.6e+04 8 14 .. 133 139 .. 115 140 .. 0.60 4 ? -1.5 0.1 0.43 5.5e+03 6 13 .. 152 159 .. 149 161 .. 0.74 5 ? -2.9 0.7 1.1 1.4e+04 6 13 .. 195 201 .. 189 203 .. 0.59 6 ? -0.6 0.1 0.22 2.9e+03 5 12 .. 212 219 .. 209 222 .. 0.75 7 ? -1.8 3.0 0.53 6.7e+03 1 8 [. 249 257 .. 249 259 .. 0.64 8 ? 3.1 0.7 0.015 1.9e+02 5 21 .. 274 290 .. 270 292 .. 0.77 9 ? -1.7 2.2 0.5 6.4e+03 7 14 .. 302 308 .. 290 309 .. 0.57 10 ? 9.5 0.0 0.00015 2 5 15 .. 327 337 .. 324 340 .. 0.87 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 0.91 Antistasin 20 GCptC 24 GC+ C FUN_001251-T1 57 GCEKC 61 99999 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00041 Antistasin 5 nCrlkCpyGfq 15 C++ Cp+Gf FUN_001251-T1 88 RCTRSCPMGFN 98 6*********6 PP == domain 3 score: -4.3 bits; conditional E-value: 2 Antistasin 8 lkCpyGf 14 l+C G+ FUN_001251-T1 133 LNCSRGY 139 3466666 PP == domain 4 score: -1.5 bits; conditional E-value: 0.43 Antistasin 6 CrlkCpyG 13 C ++Cp FUN_001251-T1 152 CVRHCPID 159 88999965 PP == domain 5 score: -2.9 bits; conditional E-value: 1.1 Antistasin 6 CrlkCpyG 13 Cr+ C + FUN_001251-T1 195 CRK-CRSD 201 555.6655 PP == domain 6 score: -0.6 bits; conditional E-value: 0.22 Antistasin 5 nCrlkCpy 12 C ++Cp+ FUN_001251-T1 212 VCVRNCPN 219 59999998 PP == domain 7 score: -1.8 bits; conditional E-value: 0.53 Antistasin 1 Cpp.lnCrl 8 Cp+ +nCr+ FUN_001251-T1 249 CPDkINCRR 257 888448875 PP == domain 8 score: 3.1 bits; conditional E-value: 0.015 Antistasin 5 nCrlkCpyGfqtDenGC 21 +C Cp Gf + + C FUN_001251-T1 274 TCVSSCPLGFFKKGRRC 290 79999*****7666655 PP == domain 9 score: -1.7 bits; conditional E-value: 0.5 Antistasin 7 rlkCpyGf 14 +C +G+ FUN_001251-T1 302 E-QCTNGY 308 2.277776 PP == domain 10 score: 9.5 bits; conditional E-value: 0.00015 Antistasin 5 nCrlkCpyGfq 15 +C++kCp+G++ FUN_001251-T1 327 SCARKCPSGYV 337 7*********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (375 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1134 (0.0443922); expected 510.9 (0.02) Passed bias filter: 261 (0.0102173); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.35s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3620.83 // Query: FUN_001252-T1 [L=518] Description: FUN_001252 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-94 309.7 10.3 3.1e-26 91.7 0.3 4.1 4 Annexin Annexin Domain annotation for each model (and alignments): >> Annexin Annexin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.0 0.1 5.5e-27 1.4e-22 2 66 .] 218 282 .. 217 282 .. 0.99 2 ! 91.7 0.3 1.2e-30 3.1e-26 1 66 [] 289 354 .. 289 354 .. 0.99 3 ! 70.3 0.1 6.1e-24 1.6e-19 2 66 .] 373 438 .. 372 438 .. 0.97 4 ! 72.6 0.1 1.1e-24 2.9e-20 1 66 [] 448 513 .. 448 513 .. 0.98 Alignments for each domain: == domain 1 score: 80.0 bits; conditional E-value: 5.5e-27 Annexin 2 dAelLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfeklllaL 66 dAe+L+kamkg+G+d k++i+ l++R+n q+q+i +Yk+ g+dL kd+k e+ G+fe++++aL FUN_001252-T1 218 DAEVLRKAMKGIGCDSKAIITLLCSRTNSQRQRIELEYKTLHGRDLLKDLKYELGGHFEDIVVAL 282 9**************************************************************98 PP == domain 2 score: 91.7 bits; conditional E-value: 1.2e-30 Annexin 1 ydAelLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfeklllaL 66 ydA L+ka+kglGtde +lieIl+tR+na++++i+ Y+k++++dLekdi ++tsG+f+k l++L FUN_001252-T1 289 YDATSLRKAVKGLGTDETVLIEILCTRTNAEIKEIKTSYQKMFSRDLEKDIAGDTSGHFKKFLISL 354 8**************************************************************987 PP == domain 3 score: 70.3 bits; conditional E-value: 6.1e-24 Annexin 2 dAe.lLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfeklllaL 66 dA+ l+k+++ +lGt+e++++++l++Rs +ql++++++Y k ++d+e++ik+e+sGd+++ ++++ FUN_001252-T1 373 DAKaLYKAGEGRLGTNESKFNTVLVSRSFPQLRATFDEYAKICKYDIEESIKREMSGDLKDGMISI 438 99999********************************************************99875 PP == domain 4 score: 72.6 bits; conditional E-value: 1.1e-24 Annexin 1 ydAelLkkamkglGtdektlieIlatRsnaqlqkireaYkkkygkdLekdiksetsGdfeklllaL 66 ++Ae+L+k+mkg Gtd++tli++++tRs+ +l +i++a+ k y +L i ++t G+++k+ll L FUN_001252-T1 448 FFAEKLYKSMKGVGTDDNTLIRVVVTRSEVDLLDIKDAFAKLYHTSLARFIADDTRGNYKKILLQL 513 69*************************************************************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (518 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 859 (0.0336269); expected 510.9 (0.02) Passed bias filter: 607 (0.023762); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4975.39 // Query: FUN_001253-T1 [L=153] Description: FUN_001253 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.087 13.4 0.0 0.44 11.1 0.0 1.9 2 EAD10 Effector-associated domain 10 Domain annotation for each model (and alignments): >> EAD10 Effector-associated domain 10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.06 1.5e+03 5 18 .. 7 20 .. 3 42 .. 0.67 2 ? 11.1 0.0 1.7e-05 0.44 17 61 .. 80 124 .. 71 129 .. 0.89 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.06 EAD10 5 eelkailerilngq 18 ++++ +l+++ +++ FUN_001253-T1 7 DDIQGLLKQLSKHN 20 45555555555544 PP == domain 2 score: 11.1 bits; conditional E-value: 1.7e-05 EAD10 17 gqqteeDieaLrqllaagdgqivlQlGkynvnIgeGkdihIGDri 61 g+++ + i aLr++ a++d+ +++Q y +++ ++ ++GDr+ FUN_001253-T1 80 GSKSLTAIRALRDAHANKDQPVLQQCPGYDIKLHPLRELQLGDRM 124 556666799**********************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (153 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 586 (0.0229399); expected 510.9 (0.02) Passed bias filter: 543 (0.0212566); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1534.95 // Query: FUN_001254-T1 [L=132] Description: FUN_001254 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.036 14.1 0.0 0.046 13.8 0.0 1.2 1 YLR146W-A YLR146W-A Domain annotation for each model (and alignments): >> YLR146W-A YLR146W-A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 1.8e-06 0.046 10 28 .. 24 42 .. 15 65 .. 0.80 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.8e-06 YLR146W-A 10 esrtLQneInsiFaeLsdl 28 +sr LQneIn+ ++ L + FUN_001254-T1 24 SSRGLQNEINGFLNCLEKV 42 89*********99988766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 746 (0.0292034); expected 510.9 (0.02) Passed bias filter: 588 (0.0230182); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1327.26 // Query: FUN_001255-T1 [L=917] Description: FUN_001255 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-46 155.6 0.0 4.5e-45 152.5 0.0 2.8 3 TPR_TNPO3_IPO13_4th Transportin-3/Importin-13 fourth TPR dom 1.3e-31 109.2 1.6 3.4e-31 107.9 0.2 2.6 2 TPR_TNPO3_IPO13_2nd Transportin-3/Importin-13 second TPR dom 8.4e-28 96.9 4.9 8.9e-28 96.8 0.2 3.2 3 TPR_TNPO3_IPO13_3rd Transportin-3/Importin-13 third TPR doma 2.2e-23 83.4 4.7 4.6e-21 75.9 0.0 4.0 3 Xpo1 Exportin 1-like protein 1.7e-05 25.2 0.9 6.3e-05 23.4 0.9 2.1 1 IBN_N Importin-beta N-terminal domain 0.00049 20.9 7.9 0.0016 19.2 0.2 4.2 4 TPR_IPO5 IPO5-like, TPR repeats 0.0018 17.6 2.6 0.0096 15.1 0.3 2.8 3 TPR_IMB1 Importin subunit beta-1-like, TPR repeat 0.0034 17.4 0.4 0.015 15.3 1.1 1.8 2 ARM_SRB8 SRB8 ARM-like domain ------ inclusion threshold ------ 0.015 15.8 0.1 0.057 14.0 0.1 2.1 1 Importin_rep_3 Importin 13 repeat Domain annotation for each model (and alignments): >> TPR_TNPO3_IPO13_4th Transportin-3/Importin-13 fourth TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 4.2 1.2e+04 12 34 .. 178 200 .. 175 205 .. 0.75 2 ? -3.1 0.0 4.3 1.2e+04 6 27 .. 337 358 .. 335 359 .. 0.85 3 ! 152.5 0.0 1.6e-48 4.5e-45 1 105 [] 627 731 .. 627 731 .. 0.99 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 4.2 TPR_TNPO3_IPO13_4th 12 pvlskvlekyqsderivErvcrc 34 ++l +++k+++d + ++ rc FUN_001255-T1 178 NLLAACVDKFSDDGTVKAKMFRC 200 56777888888888888888887 PP == domain 2 score: -3.1 bits; conditional E-value: 4.3 TPR_TNPO3_IPO13_4th 6 vieevwpvlskvlekyqsderi 27 v ++w ls++l k ++d++i FUN_001255-T1 337 VTFNFWYRLSEALYKTENDDKI 358 556799***********99998 PP == domain 3 score: 152.5 bits; conditional E-value: 1.6e-48 TPR_TNPO3_IPO13_4th 1 hPclevieevwpvlskvlekyqsderivErvcrclrfavrcvgkqsaelLeplvkqivslYashkhscfLYlgsiLvdeygedescvkgL 90 hP+l+vi evwp+ls++++ky++d +i+Er+crc+rfa+rc+gk++ +lL+plv+q+v++Y +++hscfLYlgsiLvdeyg++++cv+gL FUN_001255-T1 627 HPALAVIGEVWPLLSSICDKYRADLKIIERCCRCIRFAIRCLGKSAINLLSPLVSQMVNVYGTNPHSCFLYLGSILVDEYGDESGCVPGL 716 9***************************************************************************************** PP TPR_TNPO3_IPO13_4th 91 lemleafieptfkll 105 ++m+ a+ +p+f+ll FUN_001255-T1 717 VTMTMALSGPAFQLL 731 ************997 PP >> TPR_TNPO3_IPO13_2nd Transportin-3/Importin-13 second TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.9 0.2 1.2e-34 3.4e-31 1 90 [] 283 375 .. 283 375 .. 0.99 2 ? -3.0 0.1 4.8 1.4e+04 28 47 .. 784 806 .. 772 810 .. 0.67 Alignments for each domain: == domain 1 score: 107.9 bits; conditional E-value: 1.2e-34 TPR_TNPO3_IPO13_2nd 1 eDtdkvrnlcriFteagesllelivrep...eeflklvelilecvahedlevveiTFnfWyrLseelykekdeelrakfkpyyerlidal 87 eD+d+ nlcriFte+ges+l+ +v++p ++l+++ +il+cv+h+++ev+e+TFnfWyrLse+lyk+++++ a f+py+e+li+al FUN_001255-T1 283 EDIDRALNLCRIFTELGESFLHVLVNSPgkdLGDLRTLTIILTCVKHYQYEVAEVTFNFWYRLSEALYKTENDDKIALFRPYFETLIEAL 372 8*****************************99********************************************************** PP TPR_TNPO3_IPO13_2nd 88 ikH 90 + H FUN_001255-T1 373 CVH 375 *99 PP == domain 2 score: -3.0 bits; conditional E-value: 4.8 TPR_TNPO3_IPO13_2nd 28 p...eeflklvelilecvahedl 47 + +k ++++++c+++e FUN_001255-T1 784 RdanLSVMKFLKCLVSCATVETQ 806 44446678889999999988654 PP >> TPR_TNPO3_IPO13_3rd Transportin-3/Importin-13 third TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 1.6 4.7e+03 28 52 .. 120 144 .. 104 151 .. 0.81 2 ! 96.8 0.2 3.1e-31 8.9e-28 2 89 .] 454 541 .. 453 541 .. 0.97 3 ? -0.3 0.0 0.65 1.9e+03 37 65 .. 738 765 .. 719 787 .. 0.74 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.6 TPR_TNPO3_IPO13_3rd 28 lLlgElcewiekhpqvldpvLnfll 52 ++++El++ +++ ++l +L+ l FUN_001255-T1 120 EVVSELSQRLSTTVETLPIILEILT 144 5789999999999999999998875 PP == domain 2 score: 96.8 bits; conditional E-value: 3.1e-31 TPR_TNPO3_IPO13_3rd 2 evvpkvveailnlpenthiavrytsilLlgElcewiekhpqvldpvLnfllkgLqqkklasaaakalqsicsacrekmashfegLlqi 89 +vv + + +l+lp++ hiavr+ si+L+gEl+ewi+k+pq ldpvL+fll+ +q++kl+s++a+a++s+c++c +m++ f++L qi FUN_001255-T1 454 KVVGQFLPVMLSLPSSCHIAVRHSSIKLVGELAEWIDKQPQYLDPVLQFLLANIQDSKLSSVSASAIESLCMSCYLQMTKYFDVLAQI 541 688999999****************************************************************************998 PP == domain 3 score: -0.3 bits; conditional E-value: 0.65 TPR_TNPO3_IPO13_3rd 37 iekhpqvldpvLnfllkgLqqkklasaaa 65 i +hp+++d + + ++Lq+ +a + FUN_001255-T1 738 I-EHPDTIDDLFRLCSRCLQKFPVAFLKC 765 4.699*****9999999999988886544 PP >> Xpo1 Exportin 1-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.9 0.0 1.6e-24 4.6e-21 2 139 .. 98 233 .. 97 245 .. 0.92 2 ? 1.5 0.2 0.14 3.9e+02 90 144 .. 463 517 .. 432 549 .. 0.77 3 ? 5.2 0.1 0.01 29 37 92 .. 779 836 .. 734 871 .. 0.72 Alignments for each domain: == domain 1 score: 75.9 bits; conditional E-value: 1.6e-24 Xpo1 2 kflrnklalalaelalqeypnnWptffkdlvsllssspsglelllriLkvlpeEifdfsrtsltqernnrlkdllrsnveqilelllqileasqsa 97 ++++++l+l+la+la+q+ +W++++++l + ls+ ++l+++l+iL+vlpeE+ + ++ + ++r++++ +lr+++ +l+ll ++++ +++ FUN_001255-T1 98 HAIVTQLCLTLADLAVQM--PQWKEVVSELSQRLSTTVETLPIILEILTVLPEEVGS-HHLRVGANRREEVVTELRASAGIVLNLLAACVDKFSDD 190 5799**************..9***********************************7.99********************************8875 PP Xpo1 98 kselveavLkclsswls..wipislivnnpllnllfelLsdpel 139 + ++++c +sw+ +p +v+++ll++ f++L++ e FUN_001255-T1 191 -GTVKAKMFRCAGSWVTlgAFPPAEFVQSKLLQATFKTLHEAEC 233 .9999************99********************77665 PP == domain 2 score: 1.5 bits; conditional E-value: 0.14 Xpo1 90 ileasqsakselveavLkclsswlswipislivnnpllnllfelLsdpelreaav 144 +l+ +s + ++ ++++k ++ +wi+ + + +p+l++l+ ++d++l+ ++ FUN_001255-T1 463 MLSLPSSCHIAVRHSSIKLVGELAEWIDKQPQYLDPVLQFLLANIQDSKLSSVSA 517 4444444456777888888888888888888888888888888888887754433 PP == domain 3 score: 5.2 bits; conditional E-value: 0.01 Xpo1 37 sspsglelllriLkvlpeEifd..fsrtsltqernnrlkdllrsnveqilelllqile 92 s +++ + +l ++k l+ +++ + ++ qer + +++ l++n ++i++ l+q FUN_001255-T1 779 STLEHRDANLSVMKFLKCLVSCatVETQDNIQERLTLVQQVLSVNGQNIINGLIQACA 836 33677777777777777777777577778888889**********9999998887654 PP >> IBN_N Importin-beta N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.9 2.2e-08 6.3e-05 2 72 .. 27 91 .. 26 92 .. 0.95 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 2.2e-08 IBN_N 2 ekqLeqlekspgflskllqilsnsesplevRqlAalyLknlitkkWsdeeekslpeeekeqIknnllnlll 72 +L +l+ s ++ ++q+l + e+ ++Aa++++ +++++++ +l++++ ++++++ll++l+ FUN_001255-T1 27 SLWLHELQRSVYAWEIADQLLRLNVNV-ETSYFAAQTMRTKVQYYFH-----ELQQSQYQSLRDSLLDHLF 91 56999**********************.*******************.....****************997 PP >> TPR_IPO5 IPO5-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.23 6.6e+02 12 63 .. 100 151 .. 53 157 .. 0.69 2 ? -3.2 0.0 4.4 1.2e+04 125 148 .. 276 302 .. 221 307 .. 0.64 3 ! 19.2 0.2 5.7e-07 0.0016 9 98 .. 438 524 .. 415 548 .. 0.90 4 ? 2.2 0.2 0.095 2.7e+02 51 121 .. 727 800 .. 720 828 .. 0.73 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.23 TPR_IPO5 12 vvAelarnlidddgn.nqWpellqfLfecasspdaelresalrifesvpgifg 63 +v +l l d + qW+e++ L + s + +e + l+i++ +p+ +g FUN_001255-T1 100 IVTQLCLTLADLAVQmPQWKEVVSELSQRLSTT-VETLPIILEILTVLPEEVG 151 444444444443333356888888888876544.5555677777777777666 PP == domain 2 score: -3.2 bits; conditional E-value: 4.4 TPR_IPO5 125 laesveaedddsllka...LieLaesa 148 +++v++ed d++l+ ++eL es FUN_001255-T1 276 YEKAVNSEDIDRALNLcriFTELGESF 302 445566666666666566677777765 PP == domain 3 score: 19.2 bits; conditional E-value: 5.7e-07 TPR_IPO5 9 icdvvAelarnlidddgnnqWpellqfLfecasspdaelresalrifesvpgifgnqqeqyldvikqmlaqsLkdqeskeVrlaAvkAlv 98 i v++ +arn d++ ++l+++ + ss + + r+s++++ ++++ + +q qyld + q+l ++++d++ ++V ++A++ l+ FUN_001255-T1 438 ILFVMSTVARNVSLDSKV--VGQFLPVMLSLPSSCHIAVRHSSIKLVGELAEWID-KQPQYLDPVLQFLLANIQDSKLSSVSASAIESLC 524 566889999998886655..579*******************************9.99*****************999*******99876 PP == domain 4 score: 2.2 bits; conditional E-value: 0.095 TPR_IPO5 51 alrifesvpgifgnqqeqyldvikqmlaqsLkd....qeskeVrlaAvkA.lvafllenekeekvlkafsdllpav 121 a++++++ g+++ + + +d++ ++++++L++ + eV +aA+++ +va le+ + + + +f ++l ++ FUN_001255-T1 727 AFQLLSQERGMIE--HPDTIDDLFRLCSRCLQKfpvaFLKCEVSIAAIHCaVVASTLEHRDANLSVMKFLKCLVSC 800 7888888888888..8889999999999999995443457899999998525666677766565566665555544 PP >> TPR_IMB1 Importin subunit beta-1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.1 0.093 2.6e+02 11 53 .. 95 136 .. 85 143 .. 0.78 2 ? -2.1 0.0 0.59 1.7e+03 27 54 .. 345 373 .. 342 383 .. 0.72 3 ! 15.1 0.3 3.4e-06 0.0096 164 304 .. 433 566 .. 409 570 .. 0.82 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.093 TPR_IMB1 11 qdspkvatnccwalmnLaeqlaeeeeaetsplskyfeelvkaL 53 + s ++t+ c++l La q+ + ++ s+ls+ +++v++L FUN_001255-T1 95 NASHAIVTQLCLTLADLAVQMPQW-KEVVSELSQRLSTTVETL 136 567789**************9775.567888998888888876 PP == domain 2 score: -2.1 bits; conditional E-value: 0.59 TPR_IMB1 27 Laeqlaeeee.aetsplskyfeelvkaLl 54 L+e l ++e+ ++ + +yfe+l++aL FUN_001255-T1 345 LSEALYKTENdDKIALFRPYFETLIEALC 373 7788876654045666789******9996 PP == domain 3 score: 15.1 bits; conditional E-value: 3.4e-06 TPR_IMB1 164 tveedvflavgalasaleedFekYleaFlpfLvkALqnqeesqlcsiavglvgDisraLgekvapYcdefmnlLlenLqsealkrelkpaiLscfg 259 +e+++++++++a+ + d +k + +Flp++++ L ++ ++ ++ lvg +++ ++++ +Y+d ++++Ll+n+q+++l+ s++ FUN_001255-T1 433 ETSEAILFVMSTVARNVSLD-SKVVGQFLPVMLS-LPSSCHIAVRHSSIKLVGELAEWIDKQ-PQYLDPVLQFLLANIQDSKLSSVSA----SAIE 521 46789999999999999988.678999***9885.88888999****************987.57***************99865444....5557 PP TPR_IMB1 260 DiAlaigeeFepYlevvmqvlqqassveaeedsslemldYvlslr 304 ++++ + ++Y++v +q++ +a s+++++ds + +l + ++ FUN_001255-T1 522 SLCMSCYLQMTKYFDVLAQIVVAADSLSISNDSYIGFLKGICKVL 566 7899999********************999988776666655555 PP >> ARM_SRB8 SRB8 ARM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 1.1 5.3e-06 0.015 140 191 .. 80 131 .. 75 134 .. 0.94 2 ? -3.8 0.0 3.8 1.1e+04 132 152 .. 629 649 .. 628 649 .. 0.89 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 5.3e-06 ARM_SRB8 140 kdLfdslverlkslskeqglvarpLlaSLaeLasrlpgeeelaaqLrqdLar 191 ++L dsl++ l +l++ ++ ++ +L + La+La ++p+ +e++++L+q L+ FUN_001255-T1 80 QSLRDSLLDHLFTLRNASHAIVTQLCLTLADLAVQMPQWKEVVSELSQRLST 131 67999*******************************************9985 PP == domain 2 score: -3.8 bits; conditional E-value: 3.8 ARM_SRB8 132 vFaaiGalkdLfdslverlks 152 ++a+iG + +L +s+++++++ FUN_001255-T1 629 ALAVIGEVWPLLSSICDKYRA 649 5799*************9985 PP >> Importin_rep_3 Importin 13 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.1 2e-05 0.057 28 74 .. 811 861 .. 789 862 .. 0.82 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2e-05 Importin_rep_3 28 a....lqevvqaeGeelvetiLlgIGgeaPRslvenladvLlaLnkkypee 74 + +q+v+ +G++++ ++++ +g +P +v +vL +++ + ee FUN_001255-T1 811 ErltlVQQVLSVNGQNIINGLIQACAGAIPTYMVLDVVEVLWEFISFCREE 861 267779***********************************9999988775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (917 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 948 (0.037111); expected 510.9 (0.02) Passed bias filter: 685 (0.0268154); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.41u 0.40s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 8774.34 // Query: FUN_001256-T1 [L=586] Description: FUN_001256 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.6e-10 39.1 20.6 4.7e-05 23.4 12.3 2.4 2 ARM_ARMC5 ARMC5 1.8e-06 28.3 10.1 0.049 14.1 0.3 5.6 6 Atx10homo_assoc Spinocerebellar ataxia type 10 protein domai 1.3e-05 25.6 9.7 0.66 10.6 0.0 7.0 7 Arm Armadillo/beta-catenin-like repeat 2e-05 24.6 1.2 0.022 14.7 0.0 2.4 2 DUF5578 Family of unknown function (DUF5578) 0.00035 21.5 2.4 0.5 11.5 0.0 4.3 5 HEAT_EZ HEAT-like repeat ------ inclusion threshold ------ 0.039 14.6 4.7 38 4.9 0.1 3.8 3 V-ATPase_H_C V-ATPase subunit H 0.085 13.4 0.2 0.085 13.4 0.2 2.1 2 zf-BED BED zinc finger 0.21 12.4 0.1 37 5.2 0.0 3.0 2 HEAT_2 HEAT repeats 0.51 9.8 3.3 1.5 8.3 0.0 3.2 5 DUF913 Domain of Unknown Function (DUF913) Domain annotation for each model (and alignments): >> ARM_ARMC5 ARMC5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 1.3 1.6e-07 0.00045 75 185 .. 21 132 .. 11 142 .. 0.78 2 ! 23.4 12.3 1.7e-08 4.7e-05 82 268 .. 179 381 .. 138 384 .. 0.80 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 1.6e-07 ARM_ARMC5 75 vellk.etedsetlqmavRalriLwd.tkekreeilesgavravaellsseeeealvkavlkalaeltkgcseecaeqv.qegkglkelvslasek 167 e+l+ ++ ds+ +q a+Ral + + + ++ ++++++ v +ll+s+++++l ka+l +la t+g + +++ v +++ ++ l s ++ k FUN_001256-T1 21 QESLRfQEGDSSQQQQALRALSEILSqNRRAQDYFCSTHGLDYVISLLKSAKKSDLSKAALYTLAMATEGND--ISQRVlTKAGVFHMLRSHLQAK 114 444431345678999******8666615667899*****************************999988754..4444414577899999999999 PP ARM_ARMC5 168 kksikelalkvllnlcqq 185 ++s++ +a +ll++c FUN_001256-T1 115 NSSTTATAAFLLLTICAD 132 999999999999999976 PP == domain 2 score: 23.4 bits; conditional E-value: 1.7e-08 ARM_ARMC5 82 edsetlqmavRalriLwdtkek.reeilesgavravaellsseeeealvkavlkalaeltkgcseecaeqvqegkglkelvslasekkksik.... 172 ++ + ++++ al+ L + +++ +++++ ++ + ++++ll+ ++++ + + +l + + ++ec ++v+ +gl+ lv++++e+ ++ + FUN_001256-T1 179 SSIQLWKTVIVALQSLLQNPQNaQNQVICCRLLPMIVNLLQLATKQREIIRPTTTLLRAIVTENRECQSKVRLLGGLRALVNVLKECINEKQpcdk 274 33345579999*****9998753789****************999988888888999999999**********9***********99777777888 PP ARM_ARMC5 173 .....elalkvllnlcq.qsevRpaLGnagaiellieelkkesdaska....esskeelvnaLcllcr.eavNRvkvreagGLelllslLkdssye 257 e++++++ ++ + + +++g+++ll++ l+ +s s + ++++++++ aL+++ + N ++ + gG +ll++lL +++ e FUN_001256-T1 275 dlpfiEHVVSTIGSATAgHGMCQESTAELGLVSLLVNCLEMSSCPSLSslatRQFRTKCILALSICVEqCESNQQQLLQRGGVKLLIELLTHDQSE 370 88888999999987765277788899************9998754322112456788999999999852568************************ PP ARM_ARMC5 258 klherilsALl 268 + ++ ++ +L FUN_001256-T1 371 EFKRVAIFTLH 381 **999998886 PP >> Atx10homo_assoc Spinocerebellar ataxia type 10 protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.5 0.0 0.0039 11 4 68 .. 36 99 .. 33 113 .. 0.83 2 ? -0.6 0.0 0.62 1.7e+03 21 70 .. 95 143 .. 79 148 .. 0.74 3 ? 1.7 0.3 0.12 3.5e+02 38 67 .. 176 205 .. 174 216 .. 0.74 4 ! 5.3 0.1 0.0094 27 8 37 .. 234 266 .. 224 282 .. 0.74 5 ? 1.7 0.0 0.12 3.5e+02 4 38 .. 281 315 .. 278 325 .. 0.88 6 ! 14.1 0.3 1.7e-05 0.049 1 62 [. 329 389 .. 329 411 .. 0.89 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0039 Atx10homo_assoc 4 elvrlianltyknkevqdevrelggleliLsqcniDdnnPfikewailairnLlenneenqelia 68 + +r ++ + +n+++qd +++ +gl ++s + ++ + ++ a++ + +e+n+ q+++ FUN_001256-T1 36 QALRALSEILSQNRRAQDYFCSTHGLDYVISLLKSAKKSD-LSKAALYTLAMATEGNDISQRVLT 99 67899*************************9988877766.456778888888888877777765 PP == domain 2 score: -0.6 bits; conditional E-value: 0.62 Atx10homo_assoc 21 devrelggleliLsqcniDdnnPfikewailairnLlenneenqeliael 70 ++v + g+ +L + ++++n + a + + ++ +n e q+l +e FUN_001256-T1 95 QRVLTKAGVFHMLRS-HLQAKNSSTTATAAFLLLTICADNGEGQSLARET 143 556666666666654.5677788888889999999999999999988775 PP == domain 3 score: 1.7 bits; conditional E-value: 0.12 Atx10homo_assoc 38 iDdnnPfikewailairnLlenneenqeli 67 +D++ + i+a++ Ll+n +++q+ + FUN_001256-T1 176 MDESSIQLWKTVIVALQSLLQNPQNAQNQV 205 56666666677899******9877766654 PP == domain 4 score: 5.3 bits; conditional E-value: 0.0094 Atx10homo_assoc 8 lianltyknkevqdevrelgglel...iLsqcn 37 l+ ++ +n+e+q++vr lggl + +L++c FUN_001256-T1 234 LLRAIVTENRECQSKVRLLGGLRAlvnVLKECI 266 56677889************9765222667774 PP == domain 5 score: 1.7 bits; conditional E-value: 0.12 Atx10homo_assoc 4 elvrlianltyknkevqdevrelggleliLsqcni 38 ++v++i+++t + +q++ elg ++l+ ++ ++ FUN_001256-T1 281 HVVSTIGSATAGHGMCQESTAELGLVSLLVNCLEM 315 7899********************99999988765 PP == domain 6 score: 14.1 bits; conditional E-value: 1.7e-05 Atx10homo_assoc 1 fkrelvrlianltyknkevqdevrelggleliLsqcniDdnnPfikewailairnLlennee 62 f+++++ ++ ++ +++++q+++ ++gg++l+++ D+++ f k ai+ ++ ++ n ++ FUN_001256-T1 329 FRTKCILALSICVEQCESNQQQLLQRGGVKLLIELLTHDQSEEF-KRVAIFTLHCITRNIQD 389 799*************************************9998.67999999998877665 PP >> Arm Armadillo/beta-catenin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.019 55 23 40 .. 28 45 .. 19 46 .. 0.88 2 ? 0.2 0.0 0.44 1.3e+03 13 36 .. 60 84 .. 50 85 .. 0.83 3 ? 0.7 0.0 0.3 8.6e+02 8 33 .. 98 123 .. 92 130 .. 0.87 4 ? 2.3 0.2 0.093 2.6e+02 11 37 .. 208 236 .. 200 239 .. 0.79 5 ? 1.6 0.0 0.16 4.5e+02 11 23 .. 252 265 .. 242 269 .. 0.78 6 ? 3.2 0.1 0.051 1.5e+02 10 28 .. 302 321 .. 297 327 .. 0.83 7 ! 10.6 0.0 0.00023 0.66 4 32 .. 347 376 .. 344 380 .. 0.89 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.019 Arm 23 spdeevqeeAawALsNLa 40 +d++ q++A++ALs + FUN_001256-T1 28 EGDSSQQQQALRALSEIL 45 679999*********986 PP == domain 2 score: 0.2 bits; conditional E-value: 0.44 Arm 13 avppLvrLLs.spdeevqeeAawAL 36 +++ ++LL+ +++++ ++A+ +L FUN_001256-T1 60 GLDYVISLLKsAKKSDLSKAALYTL 84 6777899***999999999999887 PP == domain 3 score: 0.7 bits; conditional E-value: 0.3 Arm 8 vieaGavppLvrLLsspdeevqeeAa 33 + +aG+ +L + L+ +++++ Aa FUN_001256-T1 98 LTKAGVFHMLRSHLQAKNSSTTATAA 123 5689***********99999988776 PP == domain 4 score: 2.3 bits; conditional E-value: 0.093 Arm 11 aGavppLvrLLs..spdeevqeeAawALs 37 + +p+ v+LL+ ++ e++++ ++ L+ FUN_001256-T1 208 CRLLPMIVNLLQlaTKQREIIRPTTTLLR 236 5569********99998888888887775 PP == domain 5 score: 1.6 bits; conditional E-value: 0.16 Arm 11 aGavppLvrLLs.s 23 +G++++Lv+ L+ + FUN_001256-T1 252 LGGLRALVNVLKeC 265 79********9854 PP == domain 6 score: 3.2 bits; conditional E-value: 0.051 Arm 10 eaGavppLvrLLs.spdeev 28 e+G v Lv++L+ s+ +++ FUN_001256-T1 302 ELGLVSLLVNCLEmSSCPSL 321 789**********8877765 PP == domain 7 score: 10.6 bits; conditional E-value: 0.00023 Arm 4 nkqavieaGavppLvrLLs.spdeevqeeA 32 n q++++ G+v+ L++LL+ +++ee +++A FUN_001256-T1 347 NQQQLLQRGGVKLLIELLThDQSEEFKRVA 376 78999999***********99999998887 PP >> DUF5578 Family of unknown function (DUF5578) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.2 0.00067 1.9 102 188 .. 14 100 .. 10 127 .. 0.84 2 ! 14.7 0.0 7.6e-06 0.022 87 155 .. 339 406 .. 321 431 .. 0.76 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00067 DUF5578 102 vGGvltLLeiLglkqlkeedkaeaikllqlvanaGrkykeliCesygvraiaellakskseetqesaqvlleslvhgnPkyqeqvyk 188 v v L e L ++ + +++++a++ l + + r+ ++ C +g + ll ++k++ +++a l + ++gn q+ k FUN_001256-T1 14 VQDVKLLQESLRFQEGDSSQQQQALRALSEILSQNRRAQDYFCSTHGLDYVISLLKSAKKSDLSKAALYTLAMATEGNDISQRVLTK 100 55677778888899999999************************************9999999999999999999999766665555 PP == domain 2 score: 14.7 bits; conditional E-value: 7.6e-06 DUF5578 87 lsaasseryliefLevGGvltLLeiLglkqlkeedkaeaikllqlvanaGrkykeliCesygvraiael 155 ++ ++e + L GGv L+e+L+++q++e k+ ai l+ ++ + +ke es ++ i + FUN_001256-T1 339 ICVEQCESNQQQLLQRGGVKLLIELLTHDQSEE-FKRVAIFTLHCITRNIQDWKEAFVESNQRDRIPGC 406 44444555557899***************9865.6889**********************988777655 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.15 4.4e+02 3 14 .. 33 45 .. 25 56 .. 0.67 2 ? -3.4 0.0 7.9 2.3e+04 32 53 .. 63 85 .. 61 86 .. 0.70 3 ? -1.4 0.1 1.9 5.4e+03 30 52 .. 188 211 .. 185 211 .. 0.81 4 ? 4.0 0.0 0.039 1.1e+02 5 38 .. 280 315 .. 279 326 .. 0.88 5 ! 11.5 0.0 0.00018 0.5 3 43 .. 329 370 .. 327 380 .. 0.90 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.15 HEAT_EZ 3 vReaAalaLGs.l 14 ++ A++aL++ l FUN_001256-T1 33 QQQQALRALSEiL 45 5667777776633 PP == domain 2 score: -3.4 bits; conditional E-value: 7.9 HEAT_EZ 32 lLlplLndddd.eVReaAawaLg 53 + ++lL++ ++ + +aA+++L+ FUN_001256-T1 63 YVISLLKSAKKsDLSKAALYTLA 85 66778877666688888888875 PP == domain 3 score: -1.4 bits; conditional E-value: 1.9 HEAT_EZ 30 lplLlplLnddddeV.ReaAawaL 52 + +L++lL++++++ + ++++ L FUN_001256-T1 188 IVALQSLLQNPQNAQnQVICCRLL 211 568999****99998888888876 PP == domain 4 score: 4.0 bits; conditional E-value: 0.039 HEAT_EZ 5 eaAalaLGs.laeggpdllapllpellplLlplL.n 38 e+ ++++Gs a++g+++ + ++ l+ lL++ L + FUN_001256-T1 280 EHVVSTIGSaTAGHGMCQESTAELGLVSLLVNCLeM 315 577899*************************99944 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00018 HEAT_EZ 3 vReaAalaLGs.laeggpdllapllpellplLlplLndddde 43 R ++laL+ ++++++++ ++l+ + lL+ lL++d++e FUN_001256-T1 329 FRTKCILALSIcVEQCESNQQQLLQRGGVKLLIELLTHDQSE 370 58889****889***************************975 PP >> V-ATPase_H_C V-ATPase subunit H # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.014 38 38 110 .. 11 85 .. 7 91 .. 0.80 2 ? 4.2 0.2 0.024 67 22 100 .. 159 244 .. 151 251 .. 0.64 3 ? 4.8 0.0 0.015 41 43 90 .. 356 403 .. 324 409 .. 0.73 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.014 V-ATPase_H_C 38 ennfellkkLikll.eeskdkevlavalnDigelvklypegkkvleklgakerimellehe.deevryeALkavq 110 e++++ +k L + l ++ d+++ + al ++e++++ + +++ ++++ + +++ll+++ +++ + AL ++ FUN_001256-T1 11 EKEVQDVKLLQESLrFQEGDSSQQQQALRALSEILSQNRRAQDYFCSTHGLDYVISLLKSAkKSDLSKAALYTLA 85 455888999999996335667778889999999999999999999999999999999986548899999999876 PP == domain 2 score: 4.2 bits; conditional E-value: 0.024 V-ATPase_H_C 22 vHksekFWken...akkleennfellkkLikll....eeskdkevlavalnDigelvklypegkkvleklgakerimellehedee 100 +Hk+ +F + +++++e++++l k++i l ++ ++ ++ ++++ + ++v+l + k e ++ +++++ + e++e FUN_001256-T1 159 MHKEPSFIANAdewFSNMDESSIQLWKTVIVALqsllQNPQNAQNQVICCRLLPMIVNLLQLATKQREIIRPTTTLLRAIVTENRE 244 67777775544111334455556666665555444447778889999999999999988887777666666666666666666555 PP == domain 3 score: 4.8 bits; conditional E-value: 0.015 V-ATPase_H_C 43 llkkLiklleeskdkevlavalnDigelvklypegkkvleklgakeri 90 +k Li+ll++++++e va+ + +++++++ k+ + + ++ri FUN_001256-T1 356 GVKLLIELLTHDQSEEFKRVAIFTLHCITRNIQDWKEAFVESNQRDRI 403 467788888766677777888888888887777777777666666665 PP >> zf-BED BED zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 0.5 9 2.5e+04 35 40 .. 107 112 .. 105 114 .. 0.76 2 ? 13.4 0.2 3e-05 0.085 8 36 .. 531 559 .. 530 560 .. 0.85 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 9 zf-BED 35 LirHLr 40 L++HL+ FUN_001256-T1 107 LRSHLQ 112 899997 PP == domain 2 score: 13.4 bits; conditional E-value: 3e-05 zf-BED 8 relplketkakCryCgkilsrgggtsnLi 36 r++p++++ka+C +C il++++ s+L+ FUN_001256-T1 531 RKTPRDDNKARCEFCVSILNSRNFMSTLK 559 6789****************997666665 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.1 0.037 1e+02 12 58 .. 29 87 .. 17 125 .. 0.68 2 ? 5.2 0.0 0.013 37 2 25 .. 358 381 .. 357 397 .. 0.77 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.037 HEAT_2 12 pdpevraaairaLg...........eigdpealpaLlell.kdedpavRraaakaLgki 58 d +++a+raL ++ ++ l+ +++ll + ++++ +aa+ +L+ FUN_001256-T1 29 GDSSQQQQALRALSeilsqnrraqdYFCSTHGLDYVISLLkSAKKSDLSKAALYTLAMA 87 55566777778887443332222222233355999999994447789999999998865 PP == domain 2 score: 5.2 bits; conditional E-value: 0.013 HEAT_2 2 eaLlqaLlkdpdpevraaairaLg 25 + L+++L++d+++e ++ ai++L FUN_001256-T1 358 KLLIELLTHDQSEEFKRVAIFTLH 381 679999999999999999999986 PP >> DUF913 Domain of Unknown Function (DUF913) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.00052 1.5 3 45 .. 37 79 .. 35 102 .. 0.85 2 ? -3.5 0.0 1.9 5.4e+03 7 40 .. 191 224 .. 186 234 .. 0.81 3 ? -1.9 0.0 0.65 1.9e+03 339 373 .. 226 261 .. 219 265 .. 0.81 4 ? -0.8 0.0 0.3 8.6e+02 345 376 .. 338 366 .. 322 375 .. 0.67 5 ? -1.4 0.2 0.46 1.3e+03 305 361 .. 498 568 .. 447 574 .. 0.51 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00052 DUF913 3 vlqfLdtlvynvqdAfqafanakGldaivdliedevkealeev 45 +l+ L +++ + + A + f++ +Gld +++l++ k++l+++ FUN_001256-T1 37 ALRALSEILSQNRRAQDYFCSTHGLDYVISLLKSAKKSDLSKA 79 7888889999999999999999999999999998887777665 PP == domain 2 score: -3.5 bits; conditional E-value: 1.9 DUF913 7 LdtlvynvqdAfqafanakGldaivdliedevke 40 L +l++n q+A + + + l +iv+l++ +k+ FUN_001256-T1 191 LQSLLQNPQNAQNQVICCRLLPMIVNLLQLATKQ 224 7788889999999999999999999999887775 PP == domain 3 score: -1.9 bits; conditional E-value: 0.65 DUF913 339 dyidavakfLeaflsnsslcseFi.ekgGiellldl 373 ++i++++++L a++++++ c++ + gG+ +l+++ FUN_001256-T1 226 EIIRPTTTLLRAIVTENRECQSKVrLLGGLRALVNV 261 67899999999*999999998877567888888776 PP == domain 4 score: -0.8 bits; conditional E-value: 0.3 DUF913 345 akfLeaflsnsslcseFiekgGiellldlltl 376 + ++e+ s ++++ +++gG++ll++llt FUN_001256-T1 338 SICVEQCES---NQQQLLQRGGVKLLIELLTH 366 444444433...45677888888888888764 PP == domain 5 score: -1.4 bits; conditional E-value: 0.46 DUF913 305 k...........ssededvemeda.............eeaesdseeeeekesekksltdyidavakfLeaflsnsslcseF 361 + + + + a+s ++++++++++ ++ i + +f++++ s ++lc++ FUN_001256-T1 498 SrcvsvkvlkplA----------NpwnirhrkyakskDLASSIRKTPRDDNKARCEFCVSILNSRNFMSTLKSCKTLCTDH 568 1233333444440..........0333333333332122333444555555777778888888889999998888888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (586 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1280 (0.0501077); expected 510.9 (0.02) Passed bias filter: 635 (0.0248581); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.37u 0.44s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 5678.26 // Query: FUN_001257-T1 [L=343] Description: FUN_001257 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-44 152.9 20.4 2e-44 152.5 20.4 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.5 20.4 8e-49 2e-44 2 260 .] 24 282 .. 23 282 .. 0.94 Alignments for each domain: == domain 1 score: 152.5 bits; conditional E-value: 8e-49 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrir 97 N+lV++v++ n++l ++ nif+ + a++D+l+++ +lp+ ++++++ g+w +g ++Ck++ ++ ++++++s+++l + s++RY ++ +r FUN_001257-T1 24 NGLVCWVFYNNRELLNAPNIFIASVAFSDFLYCISCLPLLVISNAY-GKWIYGPIGCKATAFIATWSGLTSLMNLSVASYERYSTLAFLCTKNRTF 118 9********************************************7.*****************************************9999999* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.... RF 7tm_1 98 tkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.... 189 kr a+++ +++W++al +sl+pl g++ ++ e t+C++ +++ +++ ++sy+l+l++ +++lp++v++++y++ +r++ ks ++ks FUN_001257-T1 119 AKRTATCYSAAMWLYALFWSLMPLC--GWSGFELEGIGTSCSVRWKS-KNMLDMSYNLCLIIACYVLPVSVLVTSYYKCYREIAKSTWRAKStwgk 211 ***********************99..677787779*********99.667************************************999998888 PP .....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 k + + erk++ + +v+ v+f+++w+Py ++++++++ + +++ +i +a ++sc+NP+iY FUN_001257-T1 212 qspftK--RTFVMERKMMALFGVMTVAFLVAWTPYAVVSMISMI---AGPDVINDVTASIPAYFAKSSSCYNPVIY 282 887533..4455677*****************************...88888888888****************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (343 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 886 (0.0346839); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 3508.30 // Query: FUN_001258-T1 [L=1032] Description: FUN_001258 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-109 359.7 9.5 1.7e-21 76.8 0.0 6.7 6 SRCR Scavenger receptor cysteine-rich domain 4.2e-07 30.6 33.4 0.0004 21.1 6.6 4.0 3 EGF EGF-like domain 3.6e-06 28.0 15.3 2.9 9.1 0.0 7.3 7 SRCR_2 Scavenger receptor cysteine-rich domain ------ inclusion threshold ------ 0.028 15.3 6.6 0.028 15.3 6.6 3.7 3 hEGF Human growth factor-like EGF 0.41 11.5 35.1 0.57 11.1 10.0 3.8 3 EGF_2 EGF-like domain 9.8 6.8 20.5 1 10.0 7.3 2.9 2 EGF_Teneurin Teneurin-like EGF domain Domain annotation for each model (and alignments): >> SRCR Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.9 0.5 8.3e-25 3.5e-21 5 100 .] 28 122 .. 24 122 .. 0.89 2 ! 76.8 0.0 4.1e-25 1.7e-21 5 100 .] 143 239 .. 139 239 .. 0.90 3 ! 47.1 0.1 7.9e-16 3.4e-12 2 88 .. 253 340 .. 252 349 .. 0.75 4 ! 42.4 0.0 2.2e-14 9.4e-11 2 100 .] 363 471 .. 362 471 .. 0.80 5 ! 49.0 0.0 1.9e-16 8.3e-13 2 88 .. 486 568 .. 485 584 .. 0.82 6 ! 68.4 0.1 1.8e-22 7.6e-19 4 83 .. 602 679 .. 599 693 .. 0.88 Alignments for each domain: == domain 1 score: 75.9 bits; conditional E-value: 8.3e-25 SRCR 5 srceGrvevllngewgtvcdd...ewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesncsheedagv 97 +++Grvevl ng wg v d +w++++a vvCrqLg+ ++++al+ + g s +i++++v+C g+e+sL+qC+ +++ ++ +++d+gv FUN_001258-T1 28 LTHAGRVEVLSNGVWGRVTDGwsnQWRKQEAAVVCRQLGFAGVITALNYLPS---G-SVPIVMSRVQCVGTEKSLQQCRYNDFVNNYLYSNQDVGV 119 679******88*******9854338*****************9999776544...4.99**************************99999****** PP SRCR 98 vCs 100 vC+ FUN_001258-T1 120 VCK 122 **7 PP == domain 2 score: 76.8 bits; conditional E-value: 4.1e-25 SRCR 5 srceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn..csheedagvv 98 +++Gr+e+l++g wgt+ ++wd +da+vvCrqLg++ +++a +++ +g+ g++wl++++C+g et++++C ++++ +++ + e a+v+ FUN_001258-T1 143 LPNAGRIEILYAGVWGTIGRSNWDVNDANVVCRQLGYQAGAEAALKNRVYGPF-IGPTWLTNLQCTGYETNVMDCAHDGIANKTerSPTVEFASVI 237 5799*****88**************************9999999999998988.*************************99966334556779999 PP SRCR 99 Cs 100 C+ FUN_001258-T1 238 CK 239 96 PP == domain 3 score: 47.1 bits; conditional E-value: 7.9e-16 SRCR 2 ggssrceGrvevllngewgtvc...dde.wdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn 88 g++++++Gr+ev+ +g+wg++ ++ ++++ +vvCrqLg+++ v+ + + f+++ + w++++rC+g+e sL+qC l+ +++++ FUN_001258-T1 253 GSHQPNMGRIEVYFAGKWGAIYpwfGTSiTKKNALTVVCRQLGYTG-VSLSG-YNMFCSE-AVPPWFTNLRCKGSEISLNQCGLDYYSRTS 340 567899******99******9622234415555779*******877.54544.4445777.99*******************988877755 PP == domain 4 score: 42.4 bits; conditional E-value: 2.2e-14 SRCR 2 ggssrceGrvevllngewgtvcdde.......wdledaevvCrqLgcgkavkalseaakfgegksgkiw..lddvrCsgnetsLsqCklskwge.. 86 g+s++++Grve+ + g+wg++ d+ +++e+ +++CrqLg+++ + a+ ++k g++ ++ w + +vrC gnet++ +C +s+ + FUN_001258-T1 363 GSSTPHAGRVEIGILGTWGSIYIDRyffywlhFSSETHRIICRQLGFNDSILATVWVQK-GST-IRPRWfrYYQVRCLGNETNIRDCISSSQPQlt 456 67899*******66*******999878887778999***********999999888888.433.5666622567*************776555533 PP SRCR 87 .sncsheedagvvCs 100 +++ + +d gvvC+ FUN_001258-T1 457 rRDYYDVQDLGVVCK 471 255777899*****6 PP == domain 5 score: 49.0 bits; conditional E-value: 1.9e-16 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn 88 g+s +++G++ev + g wg++ +d++ ++v+CrqLg+++a+++ +++ fg+ +g++++ +++C+gne+ +sqC++ +++e++ FUN_001258-T1 486 GSSVSSAGTIEVSYYGVWGSIF--YIDIRVGRVICRQLGYSDAQQVFRRE-IFGQL-NGPVLIGRISCNGNESVISQCTIMAINERS 568 678899******88******97..688999************99996655.55877.*********************998888755 PP == domain 6 score: 68.4 bits; conditional E-value: 1.8e-22 SRCR 4 ssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklsk 83 +++G+vev+++g wgt+ + +w++++a+vvC qLg+++a+++ +++++ g g ++ w+++vrC gne+s+++C++s FUN_001258-T1 602 PISNAGKVEVFYAGVWGTIYSYQWNIKNAHVVCLQLGYPGAISSGESNQF-GVG-QQVAWFRNVRCLGNESSFQECPKSF 679 55789*****99******************************99666555.888.899******************8765 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 4.8 1.5e-06 0.0062 1 31 [. 704 733 .. 704 734 .. 0.96 2 ! 21.1 6.6 9.4e-08 0.0004 1 31 [. 743 772 .. 743 773 .. 0.96 3 ? 3.5 6.1 0.029 1.2e+02 1 22 [. 785 805 .. 785 806 .. 0.96 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 1.5e-06 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 Cs+ +C +G+C+d+ g C C+ G++G FUN_001258-T1 704 CSSLNCTSNGKCIDSA-AGAVCNCTGGFAGL 733 ****************.************97 PP == domain 2 score: 21.1 bits; conditional E-value: 9.4e-08 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 C++ pC+ngG+C+++ ++y C Cp tGk FUN_001258-T1 743 CKSSPCKNGGQCFSNH-SSYVCACPDRLTGK 772 99**************.************98 PP == domain 3 score: 3.5 bits; conditional E-value: 0.029 EGF 1 CspnpCsngGtCvdtprggytC 22 C ++pC n C++++ + y C FUN_001258-T1 785 CLSHPCTNKTSCFHNG-TNYLC 805 99**************.***** PP >> SRCR_2 Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.5 0.0 0.0088 37 21 39 .. 50 68 .. 34 77 .. 0.82 2 ! 9.1 0.0 0.00068 2.9 15 40 .. 156 181 .. 150 190 .. 0.88 3 ? 1.0 0.1 0.23 9.7e+02 31 42 .. 289 300 .. 283 350 .. 0.75 4 ? 2.7 0.0 0.066 2.8e+02 24 41 .. 395 412 .. 393 452 .. 0.74 5 ? 4.7 0.0 0.015 64 28 44 .. 513 529 .. 510 537 .. 0.82 6 ! 7.1 1.6 0.0028 12 14 48 .. 615 649 .. 608 720 .. 0.87 7 ? -2.6 0.0 3 1.3e+04 36 73 .. 964 999 .. 951 1006 .. 0.71 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0088 SRCR_2 21 sddWneaygkkiCeqlGys 39 s++W+++ + +C+qlG+ FUN_001258-T1 50 SNQWRKQEAAVVCRQLGFA 68 57899999999******96 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00068 SRCR_2 15 sWlpvCsddWneaygkkiCeqlGysr 40 W ++ +W+ + ++ +C+qlGy+ FUN_001258-T1 156 VWGTIGRSNWDVNDANVVCRQLGYQA 181 5999********************86 PP == domain 3 score: 1.0 bits; conditional E-value: 0.23 SRCR_2 31 kiCeqlGysrlt 42 +C+qlGy+ + FUN_001258-T1 289 VVCRQLGYTGVS 300 69******7654 PP == domain 4 score: 2.7 bits; conditional E-value: 0.066 SRCR_2 24 WneaygkkiCeqlGysrl 41 ++++ + iC+qlG++ + FUN_001258-T1 395 FSSETHRIICRQLGFNDS 412 56677789*******654 PP == domain 5 score: 4.7 bits; conditional E-value: 0.015 SRCR_2 28 ygkkiCeqlGysrltes 44 g+ iC+qlGys +++ FUN_001258-T1 513 VGRVICRQLGYSDAQQV 529 5899*******987765 PP == domain 6 score: 7.1 bits; conditional E-value: 0.0028 SRCR_2 14 ksWlpvCsddWneaygkkiCeqlGysrltesksvn 48 W ++ s +Wn + ++ +C qlGy + +s + n FUN_001258-T1 615 GVWGTIYSYQWNIKNAHVVCLQLGYPGAISSGESN 649 5799*********************8887776655 PP == domain 7 score: -2.6 bits; conditional E-value: 3 SRCR_2 36 lGysrltesksvnlsdlssnsskefvklssssketdle 73 +G +r+ + ++ +++ +++ +++ ls+++ e+ ++ FUN_001258-T1 964 MGLQRENNNRAEGIATVNE--PASYMPLSPRRPEQVVY 999 6777777777777777777..78888887777776665 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 4.6 0.0065 28 3 19 .. 711 727 .. 709 730 .. 0.82 2 ? 15.3 6.6 6.6e-06 0.028 1 19 [. 748 766 .. 748 767 .. 0.97 3 ? -3.3 0.5 5 2.1e+04 1 16 [. 796 805 .. 795 806 .. 0.48 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0065 hEGF 3 NGGtCvdgvngykCqCp 19 +G+C+d + g +C C FUN_001258-T1 711 SNGKCIDSAAGAVCNCT 727 566*************6 PP == domain 2 score: 15.3 bits; conditional E-value: 6.6e-06 hEGF 1 ClNGGtCvdgvngykCqCp 19 C+NGG+C +++++y+C Cp FUN_001258-T1 748 CKNGGQCFSNHSSYVCACP 766 ******************9 PP == domain 3 score: -3.3 bits; conditional E-value: 5 hEGF 1 ClNGGtCvdgvngykC 16 C ++Gt y+C FUN_001258-T1 796 CFHNGT------NYLC 805 444443......3455 PP >> EGF_2 EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.3 2.6 1.1e+04 7 19 .. 320 332 .. 317 333 .. 0.82 2 ? 11.1 10.0 0.00013 0.57 1 32 [] 704 735 .. 703 735 .. 0.86 3 ? 9.5 11.4 0.00041 1.8 1 32 [] 743 774 .. 743 774 .. 0.81 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.6 EGF_2 7 iCsgrGtCvnqcG 19 C+g ++ nqcG FUN_001258-T1 320 RCKGSEISLNQCG 332 5999999999998 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00013 EGF_2 1 CsasgliCsgrGtC.vnqcGk.CkCdsgyqGatC 32 Cs +l+C+ +G+C +++ G C C g+ G +C FUN_001258-T1 704 CS--SLNCTSNGKCiDSAAGAvCNCTGGFAGLHC 735 77..689*******66666955************ PP == domain 3 score: 9.5 bits; conditional E-value: 0.00041 EGF_2 1 CsasgliCsgrGtC..vnqcGkCkCdsgyqGatC 32 C++s C+++G+C +++ ++C C++ +G++C FUN_001258-T1 743 CKSS--PCKNGGQCfsNHSSYVCACPDRLTGKQC 774 8854..8*******63333368************ PP >> EGF_Teneurin Teneurin-like EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 7.3 0.00024 1 4 29 .. 708 737 .. 704 738 .. 0.87 2 ? 1.8 5.3 0.086 3.7e+02 5 30 .] 748 777 .. 745 777 .. 0.83 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00024 EGF_Teneurin 4 qCgghGtCkkGs....CaCesGWkGeeCdv 29 C ++G C++ C C G+ G +C + FUN_001258-T1 708 NCTSNGKCIDSAagavCNCTGGFAGLHCQI 737 6*******77667779************87 PP == domain 2 score: 1.8 bits; conditional E-value: 0.086 EGF_Teneurin 5 CgghGtCkkGs....CaCesGWkGeeCdve 30 C G+C + CaC +G +C+++ FUN_001258-T1 748 CKNGGQCFSNHssyvCACPDRLTGKQCEER 777 788899955555899************985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1032 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1064 (0.041652); expected 510.9 (0.02) Passed bias filter: 721 (0.0282247); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 9999.92 // Query: FUN_001259-T1 [L=1026] Description: FUN_001259 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-113 371.9 7.1 4.1e-21 75.6 0.1 6.4 6 SRCR Scavenger receptor cysteine-rich domain 1.2e-08 35.9 11.1 0.89 10.7 0.4 6.7 7 SRCR_2 Scavenger receptor cysteine-rich domain 1.9e-06 28.5 6.5 6.4e-06 26.8 6.5 2.0 1 EGF EGF-like domain 0.0007 20.4 5.9 0.0034 18.3 5.9 2.4 1 hEGF Human growth factor-like EGF ------ inclusion threshold ------ 0.098 13.2 6.3 0.37 11.4 6.3 2.0 1 Plasmod_Pvs28 Pvs28 EGF domain 0.11 13.1 0.0 0.3 11.7 0.0 1.7 1 PufQ PufQ cytochrome subunit 0.33 11.7 8.5 1.6 9.5 8.5 2.2 1 EGF_CA Calcium-binding EGF domain 0.72 10.4 5.7 2.2 8.8 5.7 1.9 1 EGF_C8A_B_C6 Complement components C8A/B/C6, EGF-like domai 3 7.8 11.2 0.1 12.7 4.5 1.9 2 EGF_TEN Teneurin EGF domain 3.2 8.5 8.9 11 6.9 8.9 2.0 1 EGF_3 EGF domain Domain annotation for each model (and alignments): >> SRCR Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.4 3.3 3.9e-24 1e-20 5 100 .] 28 122 .. 24 122 .. 0.87 2 ! 72.8 0.0 1.2e-23 3.2e-20 2 100 .] 139 238 .. 138 238 .. 0.89 3 ! 51.0 0.1 7.6e-17 1.9e-13 2 89 .. 252 340 .. 251 348 .. 0.81 4 ! 38.1 0.0 8e-13 2e-09 3 100 .] 363 469 .. 361 469 .. 0.78 5 ! 55.2 0.0 3.8e-18 9.6e-15 2 99 .. 484 583 .. 483 584 .. 0.86 6 ! 75.6 0.1 1.6e-24 4.1e-21 4 81 .. 603 678 .. 600 695 .. 0.87 Alignments for each domain: == domain 1 score: 74.4 bits; conditional E-value: 3.9e-24 SRCR 5 srceGrvevllngewgtvcdd..ewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwge.sncsheedagv 97 +++Grvev+ ng wg vc+ +w++++a vvCrqLg++++++a s + + + +++++v+C gnetsL+qC+++++ + ++ +++gv FUN_001259-T1 28 LTHAGRVEVFSNGIWGRVCNVwgSWRQKEAAVVCRQLGFQGVIAAFSYPSD----SAQFVVMSRVQCVGNETSLQQCQHDDFVNiIPLHSCQEVGV 119 679******99*********8778*****************9999776555....5889*********************9999544566678*** PP SRCR 98 vCs 100 vC+ FUN_001259-T1 120 VCK 122 **6 PP == domain 2 score: 72.8 bits; conditional E-value: 1.2e-23 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn..csheeda 95 g+s +++Gr+e+l++g wg++++ +wdl+da+vvCrqLg++ +++a +++ +g+ g++wl+++ C g+e+++++C ++k+ +++ +++ a FUN_001259-T1 139 GSSLPNAGRIEILYAGVWGAISSYNWDLHDATVVCRQLGFKAGAEAALRNRVYGPF-IGPVWLKNLMCIGSEKHVMECAHDKIANKTerSPTTRFA 233 577899******88**************************9999999988888988.************************999966324556668 PP SRCR 96 gvvCs 100 +++C+ FUN_001259-T1 234 SLICK 238 88886 PP == domain 3 score: 51.0 bits; conditional E-value: 7.6e-17 SRCR 2 ggssrceGrvevllngewgtv....cddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesnc 89 g++++++Gr+e++++g+wg++ +++++++++vvCrqLg+g+a + + + f+++ w++++rC+g+etsL+qC+++ + ++++ FUN_001259-T1 252 GSHQPNMGRIEIYYAGRWGAIypwfGTSSIKKRASTVVCRQLGYGGASLS--GYNMFCSE-AVLPWFTNLRCDGSETSLNQCDFDFYFNTSV 340 57789*******99******955445789**************9997754..44556777.8999*****************9988777554 PP == domain 4 score: 38.1 bits; conditional E-value: 8e-13 SRCR 3 gssrceGrvevllngewgtvcdde......wdledaevvCrqLgcgkavkalseaakfgegksgkiwldd..vrCsgnetsLsqCklskwgesn.. 88 +s +++Grve+ + g wg++ ++ ++ e+ +v+C+qLg+++ + + ++ + k ++ w++d ++C gnet++ +C s+ + + FUN_001259-T1 363 SSVPHAGRVEIGILGIWGSIFREHffrdkrFSFETQRVICQQLGYNDSILGSIWMRI--APKLRPRWFRDdeFHCLGNETDIRDCIPSPKPQLTrl 456 5789*******66*******987755555588899**********999988777766..3446777764434*************87777663334 PP SRCR 89 .csheedagvvCs 100 s+ +d gvvC+ FUN_001259-T1 457 gSSSAKDLGVVCK 469 4678899*****6 PP == domain 5 score: 55.2 bits; conditional E-value: 3.8e-18 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn....cshee 93 g s +++G +ev + g wg++ +++d + ++v+C+qLg+++a+++ +++ + g +++ ++++++C+gne+++sqC++ ++++n + FUN_001259-T1 484 GTSLPFAGAIEVSYYGVWGAIWGHSIDVRVGRVICHQLGYSDAQQVFRKSVF-GYM-KSPFLVKRISCNGNESAISQCRILTIDDRNywyyFHPGY 577 667899******88******************************99887766.767.89*******************999999888554334456 PP SRCR 94 dagvvC 99 agv+C FUN_001259-T1 578 GAGVQC 583 688888 PP == domain 6 score: 75.6 bits; conditional E-value: 1.6e-24 SRCR 4 ssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCkl 81 +++G+vev+++g wgt+ + +w++e+a+vvCrqLg+++a+++ ++++ g + ++ +w+++vrCsg+e+sL++C++ FUN_001259-T1 603 PISNAGQVEVFYAGVWGTIDSYQWNIENAHVVCRQLGYPGALSSGASSQF-GVR-ERTVWFSKVRCSGSESSLQDCPK 678 55789*****99******************************99666655.766.999******************75 PP >> SRCR_2 Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 0.4 0.00035 0.89 8 48 .. 36 76 .. 32 120 .. 0.74 2 ! 6.3 0.0 0.0085 22 15 40 .. 155 180 .. 149 189 .. 0.88 3 ? 0.9 0.1 0.39 9.9e+02 28 41 .. 285 298 .. 279 330 .. 0.79 4 ? 2.8 0.0 0.1 2.6e+02 29 40 .. 398 409 .. 390 414 .. 0.80 5 ? 5.1 0.0 0.019 48 27 44 .. 512 529 .. 497 542 .. 0.80 6 ! 10.1 0.1 0.00052 1.3 14 71 .. 616 672 .. 608 681 .. 0.69 7 ? -3.8 0.0 10 2.6e+04 37 75 .. 958 994 .. 956 1002 .. 0.72 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00035 SRCR_2 8 vysserksWlpvCs..ddWneaygkkiCeqlGysrltesksvn 48 v+s+ W vC+ +W+++ + +C+qlG++ s FUN_001259-T1 36 VFSN--GIWGRVCNvwGSWRQKEAAVVCRQLGFQGVIAAFSYP 76 5555..78*****85579***************8766555544 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0085 SRCR_2 15 sWlpvCsddWneaygkkiCeqlGysr 40 W + s +W+ + ++ +C+qlG++ FUN_001259-T1 155 VWGAISSYNWDLHDATVVCRQLGFKA 180 59999999****************75 PP == domain 3 score: 0.9 bits; conditional E-value: 0.39 SRCR_2 28 ygkkiCeqlGysrl 41 ++ +C+qlGy + FUN_001259-T1 285 ASTVVCRQLGYGGA 298 57889******655 PP == domain 4 score: 2.8 bits; conditional E-value: 0.1 SRCR_2 29 gkkiCeqlGysr 40 + iC+qlGy+ FUN_001259-T1 398 QRVICQQLGYND 409 578*******75 PP == domain 5 score: 5.1 bits; conditional E-value: 0.019 SRCR_2 27 aygkkiCeqlGysrltes 44 + g+ iC+qlGys +++ FUN_001259-T1 512 RVGRVICHQLGYSDAQQV 529 5799********987765 PP == domain 6 score: 10.1 bits; conditional E-value: 0.00052 SRCR_2 14 ksWlpvCsddWneaygkkiCeqlGysrltesksvnlsdlssnsskefvklssssketd 71 W ++ s +Wn + ++ +C+qlGy + +s + + + + + f+k++ s +e++ FUN_001259-T1 616 GVWGTIDSYQWNIENAHVVCRQLGYPGALSSGASSQFGVRE-RTVWFSKVRCSGSESS 672 6799999******************8766655444433333.4555666655555555 PP == domain 7 score: -3.8 bits; conditional E-value: 10 SRCR_2 37 Gysrltesksvnlsdlssnsskefvklssssketdleea 75 G +++ + k+ +++l+ + +++ls+++ e+ +++ FUN_001259-T1 958 GQKENDKNKNGPIASLNV--TAPYMHLSPRRPEHVVYSG 994 666666666667766666..8999999888888777665 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 6.5 2.5e-09 6.4e-06 1 32 [] 706 736 .. 706 736 .. 0.98 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 2.5e-09 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 C++ pC+n G+C+++ ++y CiCp+G tGkr FUN_001259-T1 706 CTSSPCKNSGQCFNNN-SSYVCICPVGLTGKR 736 9***************.*************97 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 5.9 1.3e-06 0.0034 1 21 [. 711 731 .. 711 732 .. 0.98 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.3e-06 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+N G+C +++++y+C+Cp G FUN_001259-T1 711 CKNSGQCFNNNSSYVCICPVG 731 *******************99 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 6.3 0.00015 0.37 2 33 .. 706 733 .. 705 746 .. 0.80 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00015 Plasmod_Pvs28 2 CqlKaCgengkCklglpqnsnhykCsCniGyv 33 C+ +C+ +g+C+++ + +y+C C G + FUN_001259-T1 706 CTSSPCKNSGQCFNN----NSSYVCICPVGLT 733 88889**********....********97766 PP >> PufQ PufQ cytochrome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00012 0.3 15 52 .. 748 785 .. 738 794 .. 0.71 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00012 PufQ 15 hrapkaEFavYFaiilvaalPlAlltWvlaairsrslt 52 r+ k+EF +YF+ i v+ + ++t v + + r+lt FUN_001259-T1 748 PRKGKTEFKIYFTAIAVSVIATLVVTVVCLIFKIRQLT 785 4899********99987777666666555555555554 PP >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 8.5 0.00062 1.6 7 35 .. 708 733 .. 705 740 .. 0.82 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00062 EGF_CA 7 egthnCpdentvCvNteGsfeCvCeegye 35 + C +++++C+N++ s+ C C+ g + FUN_001259-T1 708 S--SPC-KNSGQCFNNNSSYVCICPVGLT 733 4..46*.8*****************9976 PP >> EGF_C8A_B_C6 Complement components C8A/B/C6, EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 5.7 0.00085 2.2 12 28 .. 722 738 .. 711 739 .. 0.82 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00085 EGF_C8A_B_C6 12 tsCkCiCpvGtrGdaCE 28 +s CiCpvG G+ CE FUN_001259-T1 722 SSYVCICPVGLTGKRCE 738 5667************9 PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 0.5 5.3 1.4e+04 186 195 .. 340 349 .. 316 357 .. 0.40 2 ? 12.7 4.5 4e-05 0.1 22 96 .. 668 743 .. 655 756 .. 0.56 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 5.3 EGF_TEN 186 ekCekktCes 195 +C++ C++ FUN_001259-T1 340 VDCMNVLCTN 349 2233333322 PP == domain 2 score: 12.7 bits; conditional E-value: 4e-05 EGF_TEN 22 GeDCskavcpvlCsg.rGayekgkCeCeegykGeeCevkvkeceaancsgrGecie....gkCvCkpgykGkkCeektcl 96 G++ s + cp+l + G +++ C+ +y+ + +++ c+++ c+++G+c + + C+C g +Gk+Cee+ + FUN_001259-T1 668 GSESSLQDCPKLFAKyFGGRRASTALCKLQYQPA---LPT-PCTSSPCKNSGQCFNnnssYVCICPVGLTGKRCEERILN 743 5555555555543331355555555565555543...233.355556666666665222245677777777777665443 PP >> EGF_3 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 8.9 0.0042 11 7 31 .. 710 734 .. 706 737 .. 0.87 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0042 EGF_3 7 gChanAtCtntegsfkCtCkagytG 31 C + +C n+++s++C+C+ g tG FUN_001259-T1 710 PCKNSGQCFNNNSSYVCICPVGLTG 734 599999**************99886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1026 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 861 (0.0337052); expected 510.9 (0.02) Passed bias filter: 684 (0.0267763); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.42u 0.41s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 9705.65 // Query: FUN_001260-T1 [L=937] Description: FUN_001260 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-111 364.7 8.4 2.5e-21 76.4 0.0 6.6 6 SRCR Scavenger receptor cysteine-rich domain 3.8e-07 31.1 12.7 0.23 12.6 0.4 6.0 6 SRCR_2 Scavenger receptor cysteine-rich domain ------ inclusion threshold ------ 0.29 11.5 0.3 0.51 10.8 0.3 1.3 1 LRRC37AB_C LRRC37A/B like protein 1 C-terminal domain Domain annotation for each model (and alignments): >> SRCR Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.2 2.9 5.6e-24 4.8e-20 5 100 .] 23 117 .. 19 117 .. 0.88 2 ! 76.4 0.0 2.9e-25 2.5e-21 2 100 .] 134 233 .. 133 233 .. 0.90 3 ! 50.2 0.2 4.1e-17 3.5e-13 2 90 .. 247 336 .. 246 343 .. 0.80 4 ! 24.7 0.0 3.5e-09 3e-05 2 100 .] 358 464 .. 357 464 .. 0.75 5 ! 62.5 0.0 6.2e-21 5.3e-17 3 99 .. 480 578 .. 478 579 .. 0.86 6 ! 75.2 0.2 6.5e-25 5.5e-21 4 86 .. 597 677 .. 594 689 .. 0.86 Alignments for each domain: == domain 1 score: 72.2 bits; conditional E-value: 5.6e-24 SRCR 5 srceGrvevllngewgtvcdd..ewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn.csheedagv 97 +++Gr+ v+ ng wg vc+ +w++++a vvCrqLg++++++a s ++ + + +++++v+C gnetsL+qC+++++ + ++ +d+gv FUN_001260-T1 23 LTHAGRLKVFSNGVWGRVCNVwgSWRQKEAAVVCRQLGFQGVIAAFSYPSN----SAQFVVMSRVQCVGNETSLQQCQHDDFVNIVpLHSCKDVGV 114 6799*****99*********8778*****************9999776655....5789**********************999552566789*** PP SRCR 98 vCs 100 +C+ FUN_001260-T1 115 ICK 117 **7 PP == domain 2 score: 76.4 bits; conditional E-value: 2.9e-25 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn..csheeda 95 g+s +++Gr+e+l++g wg+++++++d +da+vvCrqLg++ +++a +++ fg+ g++wl++++C+gne++++ C+++k+ +++ ++ a FUN_001260-T1 134 GSSRPNAGRIEILYAGVWGAISSHNLDVNDATVVCRQLGYQAGAEAALKNRVFGPF-IGPVWLTNLQCTGNEKNMMGCSHDKIANKTeqSPASKFA 228 56788*******88**************************9999999999999999.*************************99966224556679 PP SRCR 96 gvvCs 100 +++C+ FUN_001260-T1 229 SLICK 233 99996 PP == domain 3 score: 50.2 bits; conditional E-value: 4.1e-17 SRCR 2 ggssrceGrvevllngewgtv....cddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesncs 90 g++++++Gr+ev+ +g+wg++ +++++++++vvCrqLg+g+ + + f+++ w++++rC+g+etsL+qC+l+ +++++++ FUN_001260-T1 247 GSHQPNMGRIEVHFAGRWGAIypwfGTSSMKKNASTVVCRQLGYGGDSLPVYN--MFCSE-AVLPWFTNLRCNGSETSLNQCDLDFYSNTSVD 336 57789*******88******955445789**************9876544333..35666.8999*****************99988887644 PP == domain 4 score: 24.7 bits; conditional E-value: 3.5e-09 SRCR 2 ggssrceGrvevllngewgtvcdde........wdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn. 88 g+s +++Gr+e+++ng wgt+ ++ + +++ CrqLg++++ ++ ++ g +++ ++ ++C ++et++ +C + + + FUN_001260-T1 358 GSSAPNAGRMEIKINGVWGTIGIRRlsglvryfLLTKALWFTCRQLGYNGGFLGVRWMQI---GLRRRLIWLLLNCGEKETNIGDCIYPPQPQLRl 450 57789*******88********99866666663345566789******998877665554...44455555589************8887777442 PP SRCR 89 ..csheedagvvCs 100 + +d gv+C+ FUN_001260-T1 451 psYYFAQDLGVICK 464 22555799999996 PP == domain 5 score: 62.5 bits; conditional E-value: 6.2e-21 SRCR 3 gssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn....csheed 94 + +++G +ev + gewg + +++d + ++v+CrqLg+++a+++ +++ + g+ +g+i+++++rC+gne+++sqC++ ++e+n + e FUN_001260-T1 480 TTLPFAGAIEVSYYGEWGGILGHSIDVRVGHVICRQLGYSGAQQVFRKSVF-GHM-RGPIFVKEIRCRGNESAISQCTILIINERNfwyyFDPEYG 573 56789******88****************************9999777666.888.*********************9999998885543345555 PP SRCR 95 agvvC 99 a+v C FUN_001260-T1 574 AAVLC 578 67766 PP == domain 6 score: 75.2 bits; conditional E-value: 6.5e-25 SRCR 4 ssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwge 86 +++G+vevl++g wgt+ + +w++++a+vvCrqLg+++a++a ++++ g g ++ +w+++v C gne+++++C++s +g+ FUN_001260-T1 597 PISNAGQVEVLYAGVWGTIASYQWNIKNAHVVCRQLGYPRAISAGASSQF-GGG-KQTVWFANVTCLGNESNFQECPKSFVGS 677 55789*****88*******************************9777666.766.99*******************9887665 PP >> SRCR_2 Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.6 0.4 2.7e-05 0.23 6 48 .. 29 71 .. 25 115 .. 0.75 2 ? 3.3 0.0 0.021 1.8e+02 16 40 .. 151 175 .. 145 183 .. 0.82 3 ? 1.1 0.1 0.1 8.9e+02 26 39 .. 278 291 .. 273 337 .. 0.87 4 ? -2.0 0.0 0.93 7.9e+03 32 39 .. 399 406 .. 398 419 .. 0.90 5 ! 4.5 0.0 0.0088 75 27 44 .. 507 524 .. 490 534 .. 0.79 6 ! 12.6 0.1 2.8e-05 0.24 14 44 .. 610 640 .. 602 680 .. 0.80 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 2.7e-05 SRCR_2 6 LqvysserksWlpvCs..ddWneaygkkiCeqlGysrltesksvn 48 L+v+s+ W vC+ +W+++ + +C+qlG++ s FUN_001260-T1 29 LKVFSN--GVWGRVCNvwGSWRQKEAAVVCRQLGFQGVIAAFSYP 71 788888..79*****85579***************8766555544 PP == domain 2 score: 3.3 bits; conditional E-value: 0.021 SRCR_2 16 WlpvCsddWneaygkkiCeqlGysr 40 W + s + + + ++ +C+qlGy+ FUN_001260-T1 151 WGAISSHNLDVNDATVVCRQLGYQA 175 777888888888899********86 PP == domain 3 score: 1.1 bits; conditional E-value: 0.1 SRCR_2 26 eaygkkiCeqlGys 39 ++ ++ +C+qlGy FUN_001260-T1 278 KNASTVVCRQLGYG 291 5668899******6 PP == domain 4 score: -2.0 bits; conditional E-value: 0.93 SRCR_2 32 iCeqlGys 39 +C+qlGy+ FUN_001260-T1 399 TCRQLGYN 406 7******6 PP == domain 5 score: 4.5 bits; conditional E-value: 0.0088 SRCR_2 27 aygkkiCeqlGysrltes 44 + g+ iC+qlGys +++ FUN_001260-T1 507 RVGHVICRQLGYSGAQQV 524 57999*******987665 PP == domain 6 score: 12.6 bits; conditional E-value: 2.8e-05 SRCR_2 14 ksWlpvCsddWneaygkkiCeqlGysrltes 44 W ++ s +Wn + ++ +C+qlGy r+ + FUN_001260-T1 610 GVWGTIASYQWNIKNAHVVCRQLGYPRAISA 640 67***********************988765 PP >> LRRC37AB_C LRRC37A/B like protein 1 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.3 5.9e-05 0.51 114 136 .. 763 785 .. 735 797 .. 0.83 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 5.9e-05 LRRC37AB_C 114 nklilaisvtvvvmlliiilcLi 136 n i+aisv+v+v+l++ ++cLi FUN_001260-T1 763 NSYIMAISVSVTVTLVVTVVCLI 785 5679******************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (937 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 638 (0.0249755); expected 510.9 (0.02) Passed bias filter: 549 (0.0214915); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.41s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 8892.53 // Query: FUN_001261-T1 [L=1284] Description: FUN_001261 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.8e-105 344.0 15.4 1.3e-22 80.5 0.0 6.7 6 SRCR Scavenger receptor cysteine-rich domain 9.4e-30 103.0 59.4 3e-06 27.9 6.3 6.3 5 EGF EGF-like domain 9.7e-19 67.6 59.8 0.00059 20.7 5.5 6.7 6 hEGF Human growth factor-like EGF 1.5e-12 48.2 49.1 3e-09 37.3 22.5 3.5 3 EGF_TEN Teneurin EGF domain 5.4e-07 30.6 13.8 0.81 10.8 0.3 6.7 6 SRCR_2 Scavenger receptor cysteine-rich domain 7.8e-07 29.8 85.8 0.15 12.9 6.6 6.4 6 EGF_2 EGF-like domain 9.4e-06 26.2 22.5 3.4 8.4 0.1 6.5 5 GPR128_N GPR128, N-terminal domain 0.00044 20.5 29.6 1 9.7 0.8 6.0 6 cEGF Complement Clr-like EGF-like ------ inclusion threshold ------ 0.23 12.2 63.1 2.1 9.1 6.3 6.3 5 EGF_CA Calcium-binding EGF domain Domain annotation for each model (and alignments): >> SRCR Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.2 3.1 1.7e-23 4.8e-20 5 100 .] 28 122 .. 24 122 .. 0.88 2 ! 80.5 0.0 4.6e-26 1.3e-22 2 100 .] 139 238 .. 138 238 .. 0.91 3 ! 48.0 0.3 6e-16 1.7e-12 2 86 .. 252 337 .. 251 348 .. 0.78 4 ! 17.1 0.0 2.6e-06 0.0072 2 45 .. 362 414 .. 361 433 .. 0.81 5 ! 53.0 0.0 1.6e-17 4.6e-14 2 99 .. 479 578 .. 478 579 .. 0.83 6 ! 76.1 0.1 1.1e-24 3.1e-21 4 83 .. 597 674 .. 594 689 .. 0.87 Alignments for each domain: == domain 1 score: 72.2 bits; conditional E-value: 1.7e-23 SRCR 5 srceGrvevllngewgtvcdd..ewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwge.sncsheedagv 97 +++Grvev+ ng wg vc+ +w++++a vvCrqLg++++++a s + +++ +++++v+C gne+sL+qC+ +++ + + + +++gv FUN_001261-T1 28 LTHAGRVEVFSNGIWGRVCNVwgSWHQKEAAVVCRQLGFQGVIAAFSYPSD----STQFVVMSRVQCVGNESSLQQCQYDDFVNiVSLYSCKEVGV 119 679******99*********8778*****************9999776555....5899********************99999444566789*** PP SRCR 98 vCs 100 +C+ FUN_001261-T1 120 ICK 122 **6 PP == domain 2 score: 80.5 bits; conditional E-value: 4.6e-26 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn..csheeda 95 g+s +++Gr+e+l++g wg++++++wdl da+vvCrqLg++++++a +++ fg+ g++wl++++C+gne++++ C+++k+ +++ +++ a FUN_001261-T1 139 GSSRPNAGRIEILYAGVWGAISSHNWDLIDATVVCRQLGYQDGAEAALKNRIFGPF-IGPVWLTNLQCTGNEKNMMGCSHDKIANKTeqSPSSQFA 233 56788*******88*******************************99999999999.*************************99966325667889 PP SRCR 96 gvvCs 100 +++C+ FUN_001261-T1 234 SLICK 238 99996 PP == domain 3 score: 48.0 bits; conditional E-value: 6e-16 SRCR 2 ggssrceGrvevllngewgtv....cddewdledaevvCrqLgc.gkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwge 86 g++++++Gr+ev+ +g+wg++ ++++ ++++vvCrqLg+ g+ +++++ f+++ w++++rC+g+etsL+qC+++ + + FUN_001261-T1 252 GSEQPNMGRIEVHFAGRWGAIyprfGTSSMKDKASTVVCRQLGYwGDSLSVYN---MFCSE-AVLPWFTNLRCNGSETSLNQCDVDFYLH 337 67889*******88******9333345689999**********9666665533...34666.8899*****************8876555 PP == domain 4 score: 17.1 bits; conditional E-value: 2.6e-06 SRCR 2 ggssrceGrvevllngewgtvcdde.........wdledaevvCrqLgcgkav 45 g+s +++Grvev ++g w tv d+ + + ++v+Cr+Lg+++ + FUN_001261-T1 362 GSSAPHAGRVEVETHGIWCTVGFDRhilrlfryfQHRSMSRVICRHLGYNDSI 414 67889*******88********9976888888744556899********8765 PP == domain 5 score: 53.0 bits; conditional E-value: 1.6e-17 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesncsh....ee 93 g+s +++G +ev + g wg + +++d + ++v+CrqLg+++a ++ + ++ g + +g+ +++ ++C gne+++sqC++ ++e +++h FUN_001261-T1 479 GSSLPSAGAIEVSYYGVWGGIWGRSIDVRVGHVICRQLGYSGAEEVFGNFQF-GFR-EGPLLVEGINCIGNESAISQCTILTIDEIKYRHylysGY 572 678899******88****************************9999888777.766.99*******************997777755444111145 PP SRCR 94 dagvvC 99 agv C FUN_001261-T1 573 GAGVKC 578 577777 PP == domain 6 score: 76.1 bits; conditional E-value: 1.1e-24 SRCR 4 ssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklsk 83 +++G+vev+++g wgt+ + +w++++a+vvCrqLg+++a++a ++++ g g ++ +w+++v+C gne+s+++C++s FUN_001261-T1 597 PISNAGQVEVFYAGVWGTIASYKWNIKNAHVVCRQLGYPEAISAGASSQF-GGG-QRTVWFENVKCLGNESSFQECRKSF 674 55789*****99*******************************9777666.766.99*******************7654 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 2.7 9.8e-06 0.028 1 30 [. 700 728 .. 700 730 .. 0.90 2 ! 27.9 6.3 1.1e-09 3e-06 1 32 [] 739 769 .. 739 769 .. 0.98 3 ! 27.9 6.3 1.1e-09 3e-06 1 32 [] 806 836 .. 806 836 .. 0.98 4 ! 27.9 6.3 1.1e-09 3e-06 1 32 [] 873 903 .. 873 903 .. 0.98 5 ! 27.9 6.3 1.1e-09 3e-06 1 32 [] 940 970 .. 940 970 .. 0.98 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 9.8e-06 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytG 30 Cs+ Csn G+C+d+ g C C+ ++G FUN_001261-T1 700 CSDVDCSNTGKCIDSI-AGAVCNCTDAFAG 728 99999***********.*******977766 PP == domain 2 score: 27.9 bits; conditional E-value: 1.1e-09 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 C++ pC+ngG+C+++ ++y C Cp G tGkr FUN_001261-T1 739 CKSSPCKNGGHCFSNI-SSYVCVCPDGLTGKR 769 99**************.*************97 PP == domain 3 score: 27.9 bits; conditional E-value: 1.1e-09 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 C++ pC+ngG+C+++ ++y C Cp G tGkr FUN_001261-T1 806 CKSSPCKNGGHCFSNI-SSYVCVCPDGLTGKR 836 99**************.*************97 PP == domain 4 score: 27.9 bits; conditional E-value: 1.1e-09 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 C++ pC+ngG+C+++ ++y C Cp G tGkr FUN_001261-T1 873 CKSSPCKNGGHCFSNI-SSYVCVCPDGLTGKR 903 99**************.*************97 PP == domain 5 score: 27.9 bits; conditional E-value: 1.1e-09 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 C++ pC+ngG+C+++ ++y C Cp G tGkr FUN_001261-T1 940 CKSSPCKNGGHCFSNI-SSYVCVCPDGLTGKR 970 99**************.*************97 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 2.8 0.00016 0.47 1 18 [. 705 722 .. 705 726 .. 0.95 2 ! 20.7 5.5 2.1e-07 0.00059 1 21 [. 744 764 .. 744 765 .. 0.98 3 ! 20.7 5.5 2.1e-07 0.00059 1 21 [. 811 831 .. 811 832 .. 0.98 4 ! 20.7 5.5 2.1e-07 0.00059 1 21 [. 878 898 .. 878 899 .. 0.98 5 ! 20.7 5.5 2.1e-07 0.00059 1 21 [. 945 965 .. 945 966 .. 0.98 6 ? -2.5 0.1 4.3 1.2e+04 7 17 .. 1080 1090 .. 1079 1090 .. 0.83 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00016 hEGF 1 ClNGGtCvdgvngykCqC 18 C+N G+C+d + g +C C FUN_001261-T1 705 CSNTGKCIDSIAGAVCNC 722 ****************** PP == domain 2 score: 20.7 bits; conditional E-value: 2.1e-07 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+NGG C +++++y+C+Cp G FUN_001261-T1 744 CKNGGHCFSNISSYVCVCPDG 764 *******************98 PP == domain 3 score: 20.7 bits; conditional E-value: 2.1e-07 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+NGG C +++++y+C+Cp G FUN_001261-T1 811 CKNGGHCFSNISSYVCVCPDG 831 *******************98 PP == domain 4 score: 20.7 bits; conditional E-value: 2.1e-07 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+NGG C +++++y+C+Cp G FUN_001261-T1 878 CKNGGHCFSNISSYVCVCPDG 898 *******************98 PP == domain 5 score: 20.7 bits; conditional E-value: 2.1e-07 hEGF 1 ClNGGtCvdgvngykCqCppG 21 C+NGG C +++++y+C+Cp G FUN_001261-T1 945 CKNGGHCFSNISSYVCVCPDG 965 *******************98 PP == domain 6 score: -2.5 bits; conditional E-value: 4.3 hEGF 7 CvdgvngykCq 17 +d ++gy C+ FUN_001261-T1 1080 NIDSGSGYACI 1090 57999***996 PP >> EGF_TEN Teneurin EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.9 1.2 3.5e+03 154 182 .. 322 352 .. 290 385 .. 0.61 2 ! 37.3 22.5 1.1e-12 3e-09 62 192 .. 699 841 .. 660 848 .. 0.71 3 ! 21.8 11.1 6e-08 0.00017 93 192 .. 871 975 .. 860 982 .. 0.66 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.2 EGF_TEN 154 gedceeetcsldCgehg..kCveskCkCdeg 182 g++++ ++c++d h+ C++ C+ ++ FUN_001261-T1 322 GSETSLNQCDVDFYLHSsvDCMNVLCTNETT 352 3333333333333333211233333332222 PP == domain 2 score: 37.3 bits; conditional E-value: 1.1e-12 EGF_TEN 62 eceaancsgrGecie....gkCvCkpgykGkkCe...ektcldanCsgngvCvn....gkCvCeegytgedCelekkackekcskkgklvkesgsc 146 +c++ +cs++G+ci+ C C+++++G +C+ ++ c+++ C++ g+C + CvC +g tg+ Ce++ ++++ + ++++k FUN_001261-T1 699 SCSDVDCSNTGKCIDsiagAVCNCTDAFAGLHCQiplSTPCKSSPCKNGGHCFSnissYVCVCPDGLTGKRCEKR--ILNDPQPSYPSTNKIP--P 790 5999*********97444458************9444478************87333248*************85..3433333333332222..2 PP EGF_TEN 147 vcdegytgedceeetcs.ldCgehgkCvesk....CkCdegwtGekCekkt 192 v + + t+ ++ ++ c+ + C++ g+C ++ C+C +g tG++Cek+ FUN_001261-T1 791 VDEGNETQINALSTPCKsSPCKNGGHCFSNIssyvCVCPDGLTGKRCEKRI 841 33333333344444454156888888877533344************9975 PP == domain 3 score: 21.8 bits; conditional E-value: 6e-08 EGF_TEN 93 ktcldanCsgngvCvn....gkCvCeegytgedCelekkackekcskkgklvkesgscvcdegytgedceeetcs.ldCgehgkCvesk....CkC 179 + c+++ C++ g+C + CvC +g tg+ Ce++ ++++ + ++++k v + + t+ ++ ++ c+ + C++ g+C ++ C+C FUN_001261-T1 871 TPCKSSPCKNGGHCFSnissYVCVCPDGLTGKRCEKR--ILNDPQPSYPSTNKIP--PVDEGNETQINALSTPCKsSPCKNGGHCFSNIssyvCVC 962 67************87333248*************85..3433333333332222..233333333344444454156888888877533344*** PP EGF_TEN 180 degwtGekCekkt 192 +g tG++Cek+ FUN_001261-T1 963 PDGLTGKRCEKRI 975 *********9975 PP >> SRCR_2 Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.8 0.00054 1.5 8 48 .. 36 76 .. 32 118 .. 0.73 2 ! 6.4 0.0 0.0068 19 15 40 .. 155 180 .. 149 188 .. 0.88 3 ? 1.0 0.1 0.33 9.3e+02 25 40 .. 282 297 .. 278 332 .. 0.80 4 ? 1.5 0.0 0.23 6.5e+02 27 40 .. 399 412 .. 396 417 .. 0.83 5 ? 2.6 0.0 0.1 2.9e+02 28 41 .. 508 521 .. 499 527 .. 0.84 6 ! 10.8 0.3 0.00029 0.81 14 43 .. 610 639 .. 602 672 .. 0.85 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00054 SRCR_2 8 vysserksWlpvCs..ddWneaygkkiCeqlGysrltesksvn 48 v+s+ W vC+ +W+++ + +C+qlG++ s FUN_001261-T1 36 VFSN--GIWGRVCNvwGSWHQKEAAVVCRQLGFQGVIAAFSYP 76 5555..78*****85579***************8766555544 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0068 SRCR_2 15 sWlpvCsddWneaygkkiCeqlGysr 40 W + s +W+ ++ +C+qlGy+ FUN_001261-T1 155 VWGAISSHNWDLIDATVVCRQLGYQD 180 599999******************86 PP == domain 3 score: 1.0 bits; conditional E-value: 0.33 SRCR_2 25 neaygkkiCeqlGysr 40 +++ ++ +C+qlGy FUN_001261-T1 282 KDKASTVVCRQLGYWG 297 5677899*******64 PP == domain 4 score: 1.5 bits; conditional E-value: 0.23 SRCR_2 27 aygkkiCeqlGysr 40 + ++ iC++lGy+ FUN_001261-T1 399 SMSRVICRHLGYND 412 67899*******75 PP == domain 5 score: 2.6 bits; conditional E-value: 0.1 SRCR_2 28 ygkkiCeqlGysrl 41 g+ iC+qlGys + FUN_001261-T1 508 VGHVICRQLGYSGA 521 5899*******865 PP == domain 6 score: 10.8 bits; conditional E-value: 0.00029 SRCR_2 14 ksWlpvCsddWneaygkkiCeqlGysrlte 43 W ++ s +Wn + ++ +C+qlGy ++ + FUN_001261-T1 610 GVWGTIASYKWNIKNAHVVCRQLGYPEAIS 639 67***********************87654 PP >> EGF_2 EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.6 6.2 1.8e+04 7 18 .. 319 330 .. 317 331 .. 0.74 2 ! 12.9 6.6 5.4e-05 0.15 1 32 [] 700 731 .. 700 731 .. 0.90 3 ! 11.9 10.1 0.00011 0.32 1 32 [] 739 770 .. 739 770 .. 0.82 4 ! 11.9 10.1 0.00011 0.32 1 32 [] 806 837 .. 806 837 .. 0.82 5 ! 11.9 10.1 0.00011 0.32 1 32 [] 873 904 .. 873 904 .. 0.82 6 ! 11.9 10.1 0.00011 0.32 1 32 [] 940 971 .. 940 971 .. 0.82 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 6.2 EGF_2 7 iCsgrGtCvnqc 18 C+g +t nqc FUN_001261-T1 319 RCNGSETSLNQC 330 599999988666 PP == domain 2 score: 12.9 bits; conditional E-value: 5.4e-05 EGF_2 1 CsasgliCsgrGtCvnqc.Gk.CkCdsgyqGatC 32 Cs + +Cs+ G+C+++ G C C + + G +C FUN_001261-T1 700 CS--DVDCSNTGKCIDSIaGAvCNCTDAFAGLHC 731 77..679*******99998955************ PP == domain 3 score: 11.9 bits; conditional E-value: 0.00011 EGF_2 1 CsasgliCsgrGtCvnqcG..kCkCdsgyqGatC 32 C++s C+++G+C + +C+C++g +G+ C FUN_001261-T1 739 CKSS--PCKNGGHCFSNISsyVCVCPDGLTGKRC 770 8854..8*******75554337************ PP == domain 4 score: 11.9 bits; conditional E-value: 0.00011 EGF_2 1 CsasgliCsgrGtCvnqcG..kCkCdsgyqGatC 32 C++s C+++G+C + +C+C++g +G+ C FUN_001261-T1 806 CKSS--PCKNGGHCFSNISsyVCVCPDGLTGKRC 837 8854..8*******75554337************ PP == domain 5 score: 11.9 bits; conditional E-value: 0.00011 EGF_2 1 CsasgliCsgrGtCvnqcG..kCkCdsgyqGatC 32 C++s C+++G+C + +C+C++g +G+ C FUN_001261-T1 873 CKSS--PCKNGGHCFSNISsyVCVCPDGLTGKRC 904 8854..8*******75554337************ PP == domain 6 score: 11.9 bits; conditional E-value: 0.00011 EGF_2 1 CsasgliCsgrGtCvnqcG..kCkCdsgyqGatC 32 C++s C+++G+C + +C+C++g +G+ C FUN_001261-T1 940 CKSS--PCKNGGHCFSNISsyVCVCPDGLTGKRC 971 8854..8*******75554337************ PP >> GPR128_N GPR128, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 1.9 0.034 98 6 27 .. 719 742 .. 715 756 .. 0.72 2 ! 8.0 0.5 0.0015 4.3 5 20 .. 757 772 .. 753 776 .. 0.87 3 ! 8.4 0.1 0.0012 3.4 5 20 .. 824 839 .. 820 843 .. 0.87 4 ! 8.4 0.1 0.0012 3.4 5 20 .. 891 906 .. 887 910 .. 0.87 5 ! 8.4 0.1 0.0012 3.4 5 20 .. 958 973 .. 954 977 .. 0.87 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.034 GPR128_N 6 rCiCpeeWkGlrCtia..nfCens 27 +C C++ Gl C+i C++s FUN_001261-T1 719 VCNCTDAFAGLHCQIPlsTPCKSS 742 7************98511456666 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0015 GPR128_N 5 grCiCpeeWkGlrCti 20 +C+Cp+ +G+rC++ FUN_001261-T1 757 YVCVCPDGLTGKRCEK 772 58************86 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0012 GPR128_N 5 grCiCpeeWkGlrCti 20 +C+Cp+ +G+rC++ FUN_001261-T1 824 YVCVCPDGLTGKRCEK 839 58************86 PP == domain 4 score: 8.4 bits; conditional E-value: 0.0012 GPR128_N 5 grCiCpeeWkGlrCti 20 +C+Cp+ +G+rC++ FUN_001261-T1 891 YVCVCPDGLTGKRCEK 906 58************86 PP == domain 5 score: 8.4 bits; conditional E-value: 0.0012 GPR128_N 5 grCiCpeeWkGlrCti 20 +C+Cp+ +G+rC++ FUN_001261-T1 958 YVCVCPDGLTGKRCEK 973 58************86 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 4.1 1.2e+04 7 15 .. 353 361 .. 353 363 .. 0.76 2 ? -2.6 0.1 2.6 7.5e+03 18 23 .. 699 704 .. 698 704 .. 0.91 3 ! 9.7 0.8 0.00036 1 1 20 [. 756 771 .. 756 771 .. 0.91 4 ! 9.7 0.8 0.00036 1 1 20 [. 823 838 .. 823 838 .. 0.91 5 ! 9.7 0.8 0.00036 1 1 20 [. 890 905 .. 890 905 .. 0.91 6 ! 9.7 0.8 0.00036 1 1 20 [. 957 972 .. 957 972 .. 0.91 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 4.1 cEGF 7 ppGYtLagD 15 ++GY+L FUN_001261-T1 353 NSGYELRLS 361 68***9765 PP == domain 2 score: -2.6 bits; conditional E-value: 2.6 cEGF 18 tCvDID 23 +C D+D FUN_001261-T1 699 SCSDVD 704 8****9 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00036 cEGF 1 SYtCsCppGYtLagDGrtCv 20 SY+C Cp+G t G++C+ FUN_001261-T1 756 SYVCVCPDGLT----GKRCE 771 9********99....88886 PP == domain 4 score: 9.7 bits; conditional E-value: 0.00036 cEGF 1 SYtCsCppGYtLagDGrtCv 20 SY+C Cp+G t G++C+ FUN_001261-T1 823 SYVCVCPDGLT----GKRCE 838 9********99....88886 PP == domain 5 score: 9.7 bits; conditional E-value: 0.00036 cEGF 1 SYtCsCppGYtLagDGrtCv 20 SY+C Cp+G t G++C+ FUN_001261-T1 890 SYVCVCPDGLT----GKRCE 905 9********99....88886 PP == domain 6 score: 9.7 bits; conditional E-value: 0.00036 cEGF 1 SYtCsCppGYtLagDGrtCv 20 SY+C Cp+G t G++C+ FUN_001261-T1 957 SYVCVCPDGLT----GKRCE 972 9********99....88886 PP >> EGF_CA Calcium-binding EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 5.0 0.47 1.3e+03 11 35 .. 704 727 .. 699 739 .. 0.83 2 ? 9.1 6.3 0.00073 2.1 7 35 .. 741 766 .. 736 773 .. 0.83 3 ? 8.3 7.1 0.0014 3.8 7 35 .. 808 833 .. 805 840 .. 0.82 4 ? 8.3 7.1 0.0014 3.8 7 35 .. 875 900 .. 872 907 .. 0.82 5 ? 8.3 7.1 0.0014 3.8 7 35 .. 942 967 .. 939 974 .. 0.82 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.47 EGF_CA 11 nCpdentvCvNteGsfeCvCeegye 35 +C +++++C+ ++ + C C + + FUN_001261-T1 704 DC-SNTGKCIDSIAGAVCNCTDAFA 727 6*.8*****************9997 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00073 EGF_CA 7 egthnCpdentvCvNteGsfeCvCeegye 35 + C +++++C+ ++ s+ CvC++g + FUN_001261-T1 741 S--SPC-KNGGHCFSNISSYVCVCPDGLT 766 4..46*.8******************976 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0014 EGF_CA 7 egthnCpdentvCvNteGsfeCvCeegye 35 + C +++++C+ ++ s+ CvC++g + FUN_001261-T1 808 S--SPC-KNGGHCFSNISSYVCVCPDGLT 833 4..46*.8******************976 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0014 EGF_CA 7 egthnCpdentvCvNteGsfeCvCeegye 35 + C +++++C+ ++ s+ CvC++g + FUN_001261-T1 875 S--SPC-KNGGHCFSNISSYVCVCPDGLT 900 4..46*.8******************976 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0014 EGF_CA 7 egthnCpdentvCvNteGsfeCvCeegye 35 + C +++++C+ ++ s+ CvC++g + FUN_001261-T1 942 S--SPC-KNGGHCFSNISSYVCVCPDGLT 967 4..46*.8******************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1284 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 744 (0.0291251); expected 510.9 (0.02) Passed bias filter: 505 (0.019769); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.47u 0.38s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 12333.22 // Query: FUN_001262-T1 [L=904] Description: FUN_001262 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-96 315.2 16.3 2.5e-22 79.5 0.0 6.7 6 SRCR Scavenger receptor cysteine-rich domain 4.7e-11 43.2 19.4 3.4e-05 24.5 6.1 3.2 2 EGF EGF-like domain 1.1e-05 26.1 18.1 0.0047 17.8 7.2 3.4 2 hEGF Human growth factor-like EGF 3.9e-05 24.7 10.4 1.1 10.4 0.1 6.1 6 SRCR_2 Scavenger receptor cysteine-rich domain ------ inclusion threshold ------ 0.055 13.6 0.6 0.11 12.6 0.6 1.4 1 Baculo_11_kDa Baculovirus 11 kDa family 0.25 12.0 6.6 0.35 11.5 0.1 3.3 3 GPR128_N GPR128, N-terminal domain 0.26 12.2 37.5 0.36 11.7 11.0 4.0 3 EGF_2 EGF-like domain 8.8 7.0 20.9 0.49 11.0 8.3 3.0 2 EGF_Teneurin Teneurin-like EGF domain 9.4 6.9 24.4 0.2 12.2 4.3 3.4 3 Plasmod_Pvs28 Pvs28 EGF domain Domain annotation for each model (and alignments): >> SRCR Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 1.8 3.3e-06 0.0093 64 100 .] 1 38 [. 1 38 [. 0.85 2 ! 79.5 0.0 9e-26 2.5e-22 2 100 .] 55 154 .. 54 154 .. 0.90 3 ! 48.5 0.7 4.3e-16 1.2e-12 2 98 .. 168 262 .. 167 268 .. 0.75 4 ! 43.5 0.0 1.5e-14 4.2e-11 2 100 .] 278 385 .. 277 385 .. 0.75 5 ! 56.2 0.0 1.6e-18 4.6e-15 2 99 .. 400 499 .. 399 500 .. 0.89 6 ! 75.4 0.1 1.7e-24 4.8e-21 5 82 .. 519 595 .. 515 610 .. 0.88 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 3.3e-06 SRCR 64 lddvrCsgnetsLsqCklskwge.sncsheedagvvCs 100 +++v+C g+etsL+qC+++++ + ++ +++gvvC+ FUN_001262-T1 1 MSRVQCVGSETSLQQCQHDDIVNiIPLHSCQEVGVVCK 38 689***************99999544566678*****6 PP == domain 2 score: 79.5 bits; conditional E-value: 9e-26 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn..csheeda 95 g+s +++Grve+l++g wg++++ +wdl+da+vvCrqLg++ +++a +++ +g+ g++wl++++C g+e+++++C ++++ +++ ++ a FUN_001262-T1 55 GSSLPNAGRVEILYAGVWGAISSYHWDLTDATVVCRQLGYKAGAEAALRNRVYGPF-IGPVWLKNLQCFGREKHMMECAHDGIANKTerSPATRFA 149 577899******88**************************9999999988888988.*************************99966334556779 PP SRCR 96 gvvCs 100 +v+C+ FUN_001262-T1 150 SVICK 154 9**96 PP == domain 3 score: 48.5 bits; conditional E-value: 4.3e-16 SRCR 2 ggssrceGrvevllngewgtvcddewdle....daevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesncshee 93 g++++++Gr+ev+ +g+wg++ w+++ + +vvCrqLg+ + +ls+ + f+++ w++++rC+g+etsL+qC l+ +++++++ FUN_001262-T1 168 GSHQPNMGRIEVYFAGKWGAIHPWFWTSSmkrnALTVVCRQLGYAGD--SLSGHNIFCSE-AVLPWFTNLRCKGSETSLNQCGLDFSSHTSVK--- 257 57789*******99*******976555432222899*******8663..34556667877.8999*****************77666554432... PP SRCR 94 dagvv 98 + v FUN_001262-T1 258 CMNVL 262 34455 PP == domain 4 score: 43.5 bits; conditional E-value: 1.5e-14 SRCR 2 ggssrceGrvevllngewgtvcdde......wdledaevvCrqLgcgkavkalseaakfgegksgkiwldd..vrCsgnetsLsqCklskwge... 86 g+s++++Grve+++ g wg++ ++ +++e+ +v+CrqLg+++ + + + g++ ++ w++d +rCsgne+++ +C +s + + FUN_001262-T1 278 GSSTPHAGRVEIKILGIWGSIFRKHgfsdrhFSSETQRVMCRQLGYDDSILDTIWLQI-GQS-HRVRWFRDyeIRCSGNESNIRDCISSTLPQlir 371 67899*******88******9654444444499*************988877666555.777.55667665459************8887776532 PP SRCR 87 sncsheedagvvCs 100 ++ + ++ gvvC+ FUN_001262-T1 372 QDHNFATNLGVVCK 385 23344567999996 PP == domain 5 score: 56.2 bits; conditional E-value: 1.6e-18 SRCR 2 ggssrceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCklskwgesn....cshee 93 g+s +++G +evl+ g wg +d++ ++v+CrqLg++ a+++ +++ + g+ +g+ ++++ rC+gne+++sqC++ ++++++ ++++ FUN_001262-T1 400 GSSLPSAGAIEVLYYGVWGGMLGYFIDIRVGHVICRQLGYSVAQQVFRKSVF-GHV-NGPLLIEQTRCNGNESDISQCTVIAIDHKSywyyFNERD 493 678899******88*************************9999998776655.888.*********************999988877676557788 PP SRCR 94 dagvvC 99 +agv+C FUN_001262-T1 494 RAGVRC 499 8***99 PP == domain 6 score: 75.4 bits; conditional E-value: 1.7e-24 SRCR 5 srceGrvevllngewgtvcddewdledaevvCrqLgcgkavkalseaakfgegksgkiwlddvrCsgnetsLsqCkls 82 ++ G+vev+++g wgt+ + +w++++a+vvCrqLg+++a+++ ++ +fg g++++++l++vrC gne+sL++C +s FUN_001262-T1 519 ISNVGQVEVFYAGVWGTINSYQWNIKNAHVVCRQLGYPGAISSGASS-QFGVGEHTPVLLSNVRCLGNESSLQECAKS 595 5678*****99******************************986655.559999*********************765 PP >> EGF EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 5.4 3e-08 8.5e-05 1 31 [. 621 650 .. 621 651 .. 0.96 2 ! 24.5 6.1 1.2e-08 3.4e-05 1 32 [] 660 690 .. 660 690 .. 0.97 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 3e-08 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGk 31 Cs+ +C +G+C+d++ g C+C+ G+ G FUN_001262-T1 621 CSDLNCTSNGKCIDSG-AGAVCKCADGFGGL 650 ****************.***********997 PP == domain 2 score: 24.5 bits; conditional E-value: 1.2e-08 EGF 1 CspnpCsngGtCvdtprggytCiCpeGytGkr 32 C++ pC+ngG+C+++ ++y CiCp tGkr FUN_001262-T1 660 CKSSPCKNGGQCFSNN-SSYVCICPDRLTGKR 690 99*************9.*************97 PP >> hEGF Human growth factor-like EGF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.4 3.1 8.3e-05 0.24 3 22 .] 628 647 .. 626 647 .. 0.88 2 ! 17.8 7.2 1.6e-06 0.0047 1 19 [. 665 683 .. 665 684 .. 0.97 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 8.3e-05 hEGF 3 NGGtCvdgvngykCqCppGy 22 +G+C+d + g +C C G+ FUN_001262-T1 628 SNGKCIDSGAGAVCKCADGF 647 566****************8 PP == domain 2 score: 17.8 bits; conditional E-value: 1.6e-06 hEGF 1 ClNGGtCvdgvngykCqCp 19 C+NGG+C +++++y+C+Cp FUN_001262-T1 665 CKNGGQCFSNNSSYVCICP 683 ******************9 PP >> SRCR_2 Scavenger receptor cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.5 0.0 0.0062 18 15 40 .. 71 96 .. 64 104 .. 0.87 2 ? 2.4 0.2 0.12 3.5e+02 30 92 .. 203 263 .. 178 269 .. 0.67 3 ? 1.7 0.0 0.19 5.5e+02 24 40 .. 309 325 .. 305 345 .. 0.83 4 ? 4.3 0.0 0.03 85 29 44 .. 430 445 .. 426 454 .. 0.81 5 ! 10.4 0.1 0.00039 1.1 14 43 .. 531 560 .. 521 595 .. 0.85 6 ? -2.8 0.0 4.9 1.4e+04 36 67 .. 838 867 .. 836 871 .. 0.76 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0062 SRCR_2 15 sWlpvCsddWneaygkkiCeqlGysr 40 W + s +W+ ++ +C+qlGy+ FUN_001262-T1 71 VWGAISSYHWDLTDATVVCRQLGYKA 96 59999999****************75 PP == domain 2 score: 2.4 bits; conditional E-value: 0.12 SRCR_2 30 kkiCeqlGysrltesksvnlsdlssnsskefvklssssketdleealqsrekCssgsvvslrc 92 + +C+qlGy + +++n+ ++ + f +l+ + +et+l++ + ++ +s + +++ c FUN_001262-T1 203 TVVCRQLGYAGDS-LSGHNIFCSEA-VLPWFTNLRCKGSETSLNQCGLDFSSHTSVKCMNVLC 263 569******6544.44555544444.4667777777777777777666555556666555555 PP == domain 3 score: 1.7 bits; conditional E-value: 0.19 SRCR_2 24 WneaygkkiCeqlGysr 40 ++++ + +C+qlGy FUN_001262-T1 309 FSSETQRVMCRQLGYDD 325 67778899*******65 PP == domain 4 score: 4.3 bits; conditional E-value: 0.03 SRCR_2 29 gkkiCeqlGysrltes 44 g+ iC+qlGys +++ FUN_001262-T1 430 GHVICRQLGYSVAQQV 445 889*******987765 PP == domain 5 score: 10.4 bits; conditional E-value: 0.00039 SRCR_2 14 ksWlpvCsddWneaygkkiCeqlGysrlte 43 W ++ s +Wn + ++ +C+qlGy + + FUN_001262-T1 531 GVWGTINSYQWNIKNAHVVCRQLGYPGAIS 560 68***********************76655 PP == domain 6 score: -2.8 bits; conditional E-value: 4.9 SRCR_2 36 lGysrltesksvnlsdlssnsskefvklssss 67 +G + + + k+ +++ ++ + +++ ls+++ FUN_001262-T1 838 MGLQGNDKNKNGAITNANK--TASYMDLSPRR 867 7888888888888888777..89999997665 PP >> Baculo_11_kDa Baculovirus 11 kDa family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.6 3.8e-05 0.11 29 80 .. 706 756 .. 699 758 .. 0.86 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 3.8e-05 Baculo_11_kDa 29 NrsflrdFlLvicglvvfvvivlfilLlvvilksaeaeeaekekrektllaN 80 N+s ++++++vi v++ ++v+ + L+++i k + +++++ ++ +k + +N FUN_001262-T1 706 NTS-FNSYIMVIPVSVIVTLVVTVVCLILKIRKLTAQQTTQPTNPSKIYGNN 756 444.589**************************9999999988888777666 PP >> GPR128_N GPR128, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 4.2 1.2e+04 44 67 .. 587 611 .. 585 619 .. 0.73 2 ? 1.7 1.0 0.14 4e+02 6 21 .. 640 655 .. 637 667 .. 0.81 3 ? 11.5 0.1 0.00012 0.35 5 21 .. 678 694 .. 674 713 .. 0.82 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 4.2 GPR128_N 44 ySeqtCekgtlna.GkpkAtrlcsl 67 +S+q+C k+ ++ + At+lc+l FUN_001262-T1 587 SSLQECAKSFAGFmRSGGATALCKL 611 6889999887775145678888875 PP == domain 2 score: 1.7 bits; conditional E-value: 0.14 GPR128_N 6 rCiCpeeWkGlrCtia 21 +C C++ Gl C+i FUN_001262-T1 640 VCKCADGFGGLHCQIP 655 7************974 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00012 GPR128_N 5 grCiCpeeWkGlrCtia 21 +CiCp++ +G+rC+ + FUN_001262-T1 678 YVCICPDRLTGKRCEER 694 58************976 PP >> EGF_2 EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.9 1.2 3.5e+03 6 19 .. 234 247 .. 231 264 .. 0.77 2 ? 11.7 11.0 0.00013 0.36 1 32 [] 621 652 .. 621 652 .. 0.88 3 ? 10.7 10.7 0.00026 0.73 1 32 [] 660 691 .. 660 691 .. 0.81 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 1.2 EGF_2 6 liCsgrGtCvnqcG 19 l C+g +t nqcG FUN_001262-T1 234 LRCKGSETSLNQCG 247 56999999999999 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00013 EGF_2 1 CsasgliCsgrGtCvnqc.Gk.CkCdsgyqGatC 32 Cs +l+C+ +G+C++++ G CkC +g+ G +C FUN_001262-T1 621 CS--DLNCTSNGKCIDSGaGAvCKCADGFGGLHC 652 77..789*******87777745************ PP == domain 3 score: 10.7 bits; conditional E-value: 0.00026 EGF_2 1 CsasgliCsgrGtC..vnqcGkCkCdsgyqGatC 32 C++s C+++G+C +n+ ++C C++ +G+ C FUN_001262-T1 660 CKSS--PCKNGGQCfsNNSSYVCICPDRLTGKRC 691 8854..8*******63333368***********9 PP >> EGF_Teneurin Teneurin-like EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 8.3 0.00017 0.49 4 29 .. 625 654 .. 621 655 .. 0.84 2 ? 0.7 4.6 0.28 8e+02 5 30 .] 665 694 .. 662 694 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00017 EGF_Teneurin 4 qCgghGtC.kkGs...CaCesGWkGeeCdv 29 C ++G C +G C C G+ G +C + FUN_001262-T1 625 NCTSNGKCiDSGAgavCKCADGFGGLHCQI 654 5*******6566699*************87 PP == domain 2 score: 0.7 bits; conditional E-value: 0.28 EGF_Teneurin 5 CgghGtC.kkGs....CaCesGWkGeeCdve 30 C G+C + C C +G C+++ FUN_001262-T1 665 CKNGGQCfS-NNssyvCICPDRLTGKRCEER 694 888899954.444899************985 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.6 6.7 1.9e+04 1 11 [. 257 266 .. 257 268 .. 0.49 2 ? 12.2 4.3 7.2e-05 0.2 2 32 .. 621 647 .. 620 651 .. 0.94 3 ? 5.5 5.3 0.0092 26 2 30 .. 660 684 .. 659 707 .. 0.81 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 6.7 Plasmod_Pvs28 1 kCqlKaCgeng 11 kC ++ C n+ FUN_001262-T1 257 KCMNVLCS-NE 266 45555555.44 PP == domain 2 score: 12.2 bits; conditional E-value: 7.2e-05 Plasmod_Pvs28 2 CqlKaCgengkCklglpqnsnhykCsCniGy 32 C+ +C+ ngkC+ + ++C+C +G+ FUN_001262-T1 621 CSDLNCTSNGKCIDS----GAGAVCKCADGF 647 9999***********....***********8 PP == domain 3 score: 5.5 bits; conditional E-value: 0.0092 Plasmod_Pvs28 2 CqlKaCgengkCklglpqnsnhykCsCni 30 C+ +C+ g+C+ + + +y+C C + FUN_001262-T1 660 CKSSPCKNGGQCFSN----NSSYVCICPD 684 888889999999999....********84 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (904 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 792 (0.0310041); expected 510.9 (0.02) Passed bias filter: 551 (0.0215698); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 8704.80 // Query: FUN_001264-T1 [L=443] Description: FUN_001264 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-61 207.4 0.0 5.1e-61 206.8 0.0 1.2 1 Pkinase Protein kinase domain 2.3e-33 116.1 0.0 3.7e-33 115.4 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.2e-07 32.0 0.0 2.7e-07 30.9 0.0 1.5 1 PB1 PB1 domain 3.4e-07 30.1 0.0 1.6e-05 24.7 0.0 2.1 2 ABC1 ABC1 atypical kinase-like domain 5.4e-05 22.9 0.0 0.039 13.5 0.0 2.1 2 Haspin_kinase Haspin like kinase domain 9e-05 21.8 0.0 0.00022 20.5 0.0 1.7 2 Pkinase_fungal Fungal protein kinase ------ inclusion threshold ------ 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 Kinase-like Kinase-like 0.23 12.0 0.1 0.72 10.5 0.0 1.9 2 KCTD1-15_CTD BTB/POZ domain-containing protein KCTD1/15, C Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 206.8 0.0 1.6e-64 5.1e-61 4 262 .] 157 408 .. 154 408 .. 0.91 Alignments for each domain: == domain 1 score: 206.8 bits; conditional E-value: 1.6e-64 Pkinase 4 leklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgalseee 99 l+ lG+G+ g+Vy+a++++t++i+A+K+i + + + k++++E++il ++++ +i++++++f ++++ +++E+++gg+l+ + s ++e FUN_001264-T1 157 LDILGHGNGGTVYRALHSRTNRIIAVKVIPLDVTPAVQ-KQIISELEILFQCSSLFIIEFYGAFFVENRISICTEFMDGGSLDAYGS----IPEPV 247 678*****************************999877.69***************************************9999886....***** PP Pkinase 100 akkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYmAPEvlkskkygkkvDvWslGvilyelltgkp 195 + +i+ ++++gl+yl++ +++HrD+Kp+NiL++++g++K++DFG++++l +s +t++vgt+ YmAPE + + +y+ + +WslGv l+e+ g+ FUN_001264-T1 248 LGRIAVSVVKGLRYLWELKIMHRDVKPSNILVSTRGQVKLCDFGVSRQLVNSI-ATTYVGTHAYMAPERILGDEYSIRSELWSLGVSLLEMALGRF 342 ***************************************************99.****************************************** PP Pkinase 196 pfsaekekekvekeldqlekilki..elkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 p++ +++ ++ + + ++ +++ + +++s+ + ++++++++k p +R+t e +l hp++ FUN_001264-T1 343 PYPTDSRG--GAETFLPIALLQ-CivHENPPCLPGDKFSPGFVNFVSQCMQKSPLSRMTPEAVLTHPFI 408 ***33333..233333333333.235667777788999*****************************97 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 115.4 0.0 1.2e-36 3.7e-33 2 251 .. 155 399 .. 154 405 .. 0.85 Alignments for each domain: == domain 1 score: 115.4 bits; conditional E-value: 1.2e-36 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkkk 96 ++ + lG+G+ G+Vy++ + +++ +avK++ + + ++++++e++++ ++s i++++g+ e+++ i te+++gGsL+ + FUN_001264-T1 155 QYLDILGHGNGGTVYRALHS----RTNRIIAVKVIPLDVTPAVQKQIISELEILFQCSSLFIIEFYGAFFVENRISICTEFMDGGSLDAY----- 240 56678************999....9999************************************************************99..... PP PK_Tyr_Ser-Thr 97 eklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDvWsfG 191 ++ + l ++a+ + kG++yL + k++Hrd+ N+Lvs++ +vk++DfG++r++ ++ +++ +mapE + +++ +s Ws G FUN_001264-T1 241 GSIPEPVLGRIAVSVVKGLRYLWELKIMHRDVKPSNILVSTRGQVKLCDFGVSRQL----VNSIATTYVGTHAYMAPERILGDEYSIRSELWSLG 331 678999999***********************************************....5555666777889********************** PP PK_Tyr_Ser-Thr 192 vllwEiftlgeepykglknee........vlell.eegerleqpencpeelyelmkeCweedpeeRptf 251 v l E++ g+ py++ + +l+ + +e+ + ++ ++ +++++C++++p +R t FUN_001264-T1 332 VSLLEMAL-GRFPYPTDSRGGaetflpiaLLQCIvHENPPCLPGDKFSPGFVNFVSQCMQKSPLSRMTP 399 *****987.****87654322112222225555534455555556777888888888888888888775 PP >> PB1 PB1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.0 8.4e-11 2.7e-07 17 69 .. 22 73 .. 13 85 .. 0.87 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 8.4e-11 PB1 17 svsrgisfeeLrakvekrlklsdedlklkYpdedgdlVsltsDeDLeealeea 69 v+ +i f+++++ ++++++ + + + + Y de+gd ++++ De+L+++++ + FUN_001264-T1 22 TVHQNIVFRDVLEAISQVMPNT-TATAFEYDDEEGDRITVRGDEELQAMISGY 73 688999***************7.***************************987 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.019 62 44 83 .. 166 207 .. 163 221 .. 0.67 2 ! 24.7 0.0 4.9e-09 1.6e-05 146 226 .. 227 304 .. 218 312 .. 0.85 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.019 ABC1 44 aqVhkArlk.dgeeVavKvqrpgvkkriesDl.kllklllkv 83 ++V++A + +++ +avKv +v+ ++++ + + l++l++ FUN_001264-T1 166 GTVYRALHSrTNRIIAVKVIPLDVTPAVQKQIiSELEILFQC 207 78****8887999******86555555544431334444444 PP == domain 2 score: 24.7 bits; conditional E-value: 4.9e-09 ABC1 146 LtmeyvdGikiddlealeeagidrkeiaeklvelfleqifedgffhaDphpGNllvrkdgelvllDfGlmgeldekfrkkl 226 + +e++dG ++d + ++ + +ia ++v+ l+ + e +++h D p+N+lv+++g++ l DfG++++l ++ ++ FUN_001264-T1 227 ICTEFMDGGSLDAYGSIP--EPVLGRIAVSVVK-GLRYLWELKIMHRDVKPSNILVSTRGQVKLCDFGVSRQLVNSIATTY 304 568999999999999999..5566677777776.578999*******************************9988776666 PP >> Haspin_kinase Haspin like kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.00088 2.8 72 146 .. 119 200 .. 77 214 .. 0.70 2 ! 13.5 0.0 1.2e-05 0.039 228 256 .. 268 296 .. 259 307 .. 0.86 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.00088 Haspin_kinase 72 sqeevkefdeallsqllelckikqvieeedlvskkad.....seklssevyrlke..kdeevvlKvipldvledvtiskels 146 ++++v++ + l ++ e+ +i++++ + +++ + + ++ vyr+ + ++ +++Kvipldv + v+ +++ FUN_001264-T1 119 NTVPVVKSQPKLGLHKTEHGDIRNLLANGQVSHTDIQyldilGHGNGGTVYRALHsrTNRIIAVKVIPLDVTPAVQKQIISE 200 555555555555556667777777777777666666666666777788899987656788999******9999998764333 PP == domain 2 score: 13.5 bits; conditional E-value: 1.2e-05 Haspin_kinase 228 EHRdLhldniLvdknlnvtlidyklaRak 256 HRd + niLv ++v l+d+ ++R FUN_001264-T1 268 MHRDVKPSNILVSTRGQVKLCDFGVSRQL 296 5**************************64 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.53 1.7e+03 98 118 .. 64 84 .. 57 104 .. 0.84 2 ! 20.5 0.0 7e-08 0.00022 294 376 .. 254 327 .. 123 330 .. 0.88 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.53 Pkinase_fungal 98 ekfirvvlgfllmneeeLGfd 118 e++ ++ g+l+m++e+L d FUN_001264-T1 64 EELQAMISGYLWMTSERLRKD 84 6778899*******9998555 PP == domain 2 score: 20.5 bits; conditional E-value: 7e-08 Pkinase_fungal 294 daikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielsessasgarertGTleFmaiellkgeeHtyrhDL 376 ++k++r L + +i+HrD+ +Ni++ + + L D+ ++ +l + s a + +GT ++ma e + g e ++r L FUN_001264-T1 254 SVVKGLRYLW-ELKIMHRDVKPSNILVS-----TRGQVKLCDFGVSRQLVN---SIATTYVGTHAYMAPERILGDEYSIRSEL 327 689*******.*****************.....567889********9994...66789************999988888777 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 1.1e-05 0.036 152 262 .. 253 355 .. 247 370 .. 0.72 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.1e-05 Kinase-like 152 lqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvvsevekgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysiwcl 247 + +++ +L ++ ++h ++++ n+l +g v+l +f+ + v++++ ++ + +r + ++ + W lG++++ ++ FUN_001264-T1 253 VSVVKGLRYLWELKIMHRDVKPSNILVSTRGQVKLCDFGV----SRQLVNSIATTYVGTHAYMAP----ERILGDEYSIRSELWSLGVSLLEMALG 340 556777789999**************************84....344445555444332222221....111223678899999999999999988 PP Kinase-like 248 klPltlvaeeakeew 262 P + ++ e + FUN_001264-T1 341 RFPYPTDSRGGAETF 355 888877777666655 PP >> KCTD1-15_CTD BTB/POZ domain-containing protein KCTD1/15, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.00023 0.72 3 49 .. 7 54 .. 5 70 .. 0.84 2 ? -2.5 0.0 2.5 8e+03 25 53 .. 187 215 .. 178 220 .. 0.76 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00023 KCTD1-15_CTD 3 vvvhvspdlgerislsaerali.eevfPevsevledsknaswnqdsky 49 +v++++pd ge + + +++++ +v+ +s+v+ ++++++++ d + FUN_001264-T1 7 LVIRIVPDEGEAVDWTVHQNIVfRDVLEAISQVMPNTTATAFEYDDEE 54 789***********99988865399**************999988765 PP == domain 2 score: -2.5 bits; conditional E-value: 2.5 KCTD1-15_CTD 25 eevfPevsevledsknaswnqdskyvirf 53 +v P v++ + ++ + ++ s ++i f FUN_001264-T1 187 LDVTPAVQKQIISELEILFQCSSLFIIEF 215 57888888888888888888888888777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (443 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 420 (0.0164416); expected 510.9 (0.02) Passed bias filter: 409 (0.016011); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4325.73 // Query: FUN_001267-T1 [L=166] Description: FUN_001267 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-57 193.9 9.4 1.8e-57 193.6 9.4 1.0 1 TspO_MBR TspO/MBR family Domain annotation for each model (and alignments): >> TspO_MBR TspO/MBR family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 193.6 9.4 7.1e-62 1.8e-57 2 144 .. 13 156 .. 12 157 .. 0.96 Alignments for each domain: == domain 1 score: 193.6 bits; conditional E-value: 7.1e-62 TspO_MBR 2 vllplavgllgglltsksiskwykslkkPswtppnwvfgpvwtvlyilmgiaaylvwkaggsekkak.kalalyalqlalnllWsplffglrslgl 96 vllp+++g+lgg++t+++i+ wy+ l+kPsw+ppnw+fgp+wt+ly mg+a+ylvw++gg+ + al+ly+++laln++W+p+ffg ++lgl FUN_001267-T1 13 VLLPNVGGFLGGFITRSQIKGWYEGLNKPSWRPPNWLFGPMWTTLYSSMGYASYLVWRDGGGFDGDAkLALTLYGTNLALNWMWTPIFFGSHKLGL 108 89**********************************************************976554459*************************** PP TspO_MBR 97 alvdilallllvlalilvfkkisklaalllvPYlaWlsfatylnaaiw 144 a+ +i++l+l ++ ++++f++i+k+aa ll+PYl+W+++at+ln+++w FUN_001267-T1 109 AFGEICVLWLNIAGCLYTFYPINKTAAGLLLPYLGWVTLATALNYKMW 156 ***********************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (166 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 510 (0.0199648); expected 510.9 (0.02) Passed bias filter: 354 (0.0138579); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1635.87 // Query: FUN_001268-T1 [L=387] Description: FUN_001268 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0053 17.4 3.3 1.1 10.0 0.2 2.6 2 JIP_LZII JNK-interacting protein leucine zipper II ------ inclusion threshold ------ 0.013 16.5 6.2 1.9 9.5 1.0 2.6 2 DUF2408 Protein of unknown function (DUF2408) 0.024 15.2 1.2 0.76 10.4 0.2 2.3 2 Rx_N Rx N-terminal domain 0.065 13.4 4.7 4.8 7.4 0.9 2.4 2 TBCA_PH PH domain-containing proteins, TBCA domain 0.12 12.8 6.7 4.9 7.7 0.2 2.7 2 Prefoldin_2 Prefoldin subunit 0.15 12.9 0.1 0.15 12.9 0.1 3.3 3 Orf78 Orf78 (ac78) 0.17 12.6 4.4 3 8.6 0.3 2.6 2 DUF4600 Domain of unknown function (DUF4600) 0.18 12.4 1.2 2.4 8.8 0.1 2.7 2 DUF1192 Protein of unknown function (DUF1192) 0.26 12.1 4.5 9.3 7.1 0.3 2.8 2 Spectrin_7 Animal spectrin repeats 0.39 11.4 16.0 0.41 11.3 1.2 2.9 3 OmpH Outer membrane protein (OmpH-like) 0.41 11.1 4.2 6.6 7.2 0.3 2.5 2 Nas2_N Nas2 N_terminal domain 0.42 11.8 5.5 7 7.9 0.6 2.6 2 SlyX SlyX 0.86 10.1 22.6 0.13 12.8 1.4 2.9 3 Myo5a Unconventional myosin-Va domain 1.3 10.2 9.9 6.4 8.0 0.2 3.1 3 DUF6779 Domain of unknown function (DUF6779) 1.3 9.5 11.5 1.8 9.1 2.6 2.8 2 Ribosomal_L29 Ribosomal L29 protein 1.4 8.8 4.4 11 6.0 1.1 2.4 2 Fzo_mitofusin fzo-like conserved region 1.5 9.5 9.9 2.4 8.8 1.1 2.8 2 bZIP_1 bZIP transcription factor 1.6 9.1 3.4 11 6.4 0.3 2.4 2 MerR_2 MerR HTH family regulatory protein 2.3 9.3 11.1 7 7.8 0.4 2.8 3 DUF7900 Domain of unknown function (DUF7900) 3 8.9 10.1 4 8.5 2.8 2.8 2 ZapB Cell division protein ZapB 5.7 6.9 13.4 5.2 7.1 0.9 2.3 2 FapA Flagellar Assembly Protein A beta solenoid dom 7 7.4 11.0 6.7 7.5 0.9 2.9 2 Spc24 Spc24 subunit of Ndc80 7.6 7.3 15.5 3.5 8.4 3.2 3.2 3 Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 9 7.0 8.8 11 6.7 1.1 3.4 3 DUF7365 Coiled-coil region of unknown function (DUF736 Domain annotation for each model (and alignments): >> JIP_LZII JNK-interacting protein leucine zipper II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.2 0.001 1.1 29 57 .. 32 60 .. 23 69 .. 0.89 2 ! 7.4 0.3 0.0068 7.3 34 57 .. 169 192 .. 162 203 .. 0.79 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.001 JIP_LZII 29 ddLIarVdeLssekeilreEleslqevke 57 ddL a+V +L +e + lr+ l++ ++k+ FUN_001268-T1 32 DDLAAKVKQLEKELKSLRQQLKGKDNLKS 60 8*********************9988876 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0068 JIP_LZII 34 rVdeLssekeilreEleslqevke 57 + d+L e + l+eEl+sl+++ + FUN_001268-T1 169 KADDLVDEVKQLKEELRSLHQLLK 192 679999999999999999988643 PP >> DUF2408 Protein of unknown function (DUF2408) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.4 0.0021 2.3 30 69 .. 31 70 .. 15 110 .. 0.78 2 ? 9.5 1.0 0.0018 1.9 34 73 .. 164 212 .. 124 236 .. 0.77 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0021 DUF2408 30 kkeskkeelkelkkeLkeieskrdeegkfassetke.vvek 69 ++ ++++k+l+keLk + ++ + +++++s+e + e+ FUN_001268-T1 31 ADD-LAAKVKQLEKELKSLRQQLKGKDNLKSNEPPSkTTEE 70 222.489******************9999999654413333 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0018 DUF2408 34 k.........keelkelkkeLkeieskrdeegkfassetkevvekgqav 73 + +e+k+lk+eL+ + + +e+++++s+e + + ++++ FUN_001268-T1 164 AtvnskaddlVDEVKQLKEELRSLHQLLKEKDNLKSNEPPSKATEEERT 212 033334455599**********************999876666555554 PP >> Rx_N Rx N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.1 0.11 1.2e+02 21 45 .. 32 56 .. 14 68 .. 0.71 2 ? 10.4 0.2 0.00071 0.76 19 52 .. 169 202 .. 151 210 .. 0.81 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.11 Rx_N 21 kgvkkelekLkdeLesiqafLedae 45 ++ ++++L++eL+s+++ L+ + FUN_001268-T1 32 DDLAAKVKQLEKELKSLRQQLKGKD 56 4556677888888888777776655 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00071 Rx_N 19 llkgvkkelekLkdeLesiqafLedaeekqekde 52 + ++ +e+++Lk+eL+s++++L++ ++ + +++ FUN_001268-T1 169 KADDLVDEVKQLKEELRSLHQLLKEKDNLKSNEP 202 5667889*****************9998776665 PP >> TBCA_PH PH domain-containing proteins, TBCA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.2 0.0048 5.1 90 118 .. 34 62 .. 25 74 .. 0.76 2 ? 7.4 0.9 0.0045 4.8 3 40 .. 162 199 .. 160 210 .. 0.88 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0048 TBCA_PH 90 awaeysrLEselevlrqkLqeqlnlslqs 118 a+ ++LE+el+ lrq+L+ + nl++++ FUN_001268-T1 34 LAAKVKQLEKELKSLRQQLKGKDNLKSNE 62 5677899************9998885544 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0045 TBCA_PH 3 aesdvdvklsrLceqdkilqelekklqqLkedKdkLes 40 + +v+ k + L + k l+e+ + l+qL ++Kd+L+s FUN_001268-T1 162 THATVNSKADDLVDEVKQLKEELRSLHQLLKEKDNLKS 199 5678899999999999999999999****999999986 PP >> Prefoldin_2 Prefoldin subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.2 0.0046 4.9 70 93 .. 30 53 .. 16 60 .. 0.70 2 ? 7.0 1.8 0.0075 8 10 46 .. 166 202 .. 162 221 .. 0.88 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0046 Prefoldin_2 70 rketlekeiktlekqleklekele 93 r+++l +++k+lek+l++l+++l+ FUN_001268-T1 30 RADDLAAKVKQLEKELKSLRQQLK 53 556666666666666666666654 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0075 Prefoldin_2 10 lqqqlqqlaqqikqleeqlkelelvleelelldedtk 46 +++ ++l+ ++kql+e+l+ l++ l+e ++l++++ FUN_001268-T1 166 VNSKADDLVDEVKQLKEELRSLHQLLKEKDNLKSNEP 202 57889999********************999998866 PP >> Orf78 Orf78 (ac78) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 2.5 4 4.2e+03 18 46 .. 122 150 .. 52 170 .. 0.72 2 ? -1.7 0.2 4.7 5e+03 31 49 .. 201 219 .. 189 240 .. 0.39 3 ? 12.9 0.1 0.00014 0.15 22 94 .. 276 349 .. 254 357 .. 0.59 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 4 Orf78 18 PLKLAlnddaddndkaenkkekqsvaakn 46 PL L + d+++++ +++++++++++a+n FUN_001268-T1 122 PLSLSSSSDKTTATTKKTTATTKKTTATN 150 55555544343333333333333333333 PP == domain 2 score: -1.7 bits; conditional E-value: 4.7 Orf78 31 dkaenkkekqsvaakneie 49 + +++++e++++ +++e+ FUN_001268-T1 201 EPPSKATEEERTLSTKEKA 219 2222222222222222222 PP == domain 3 score: 12.9 bits; conditional E-value: 0.00014 Orf78 22 Alnddaddndkaenkkekqsvaakneieekesn.aekasalnillisllavvcvlvllyviyYfvilrerrkss 94 A n++a++++++ ++ + ++++++ ++++++n ae+ + + ++ s + +++l++v++ ++i +r+k + FUN_001268-T1 276 AANKEAKAASSNPVTHATVNSKDQKTLSTEKANqAERGKDGLLIYRSHFPTIFMVLLVIVVVTYMIYHNRNKVH 349 34444444444444444444444444444443315555555555555555555555666666667777776655 PP >> DUF4600 Domain of unknown function (DUF4600) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.3 0.0028 3 52 76 .. 31 55 .. 17 105 .. 0.75 2 ? 5.2 0.5 0.033 35 53 94 .. 171 211 .. 138 239 .. 0.74 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0028 DUF4600 52 vesLkkllkqlekekrslenqlkdl 76 ++L +kqleke +sl++qlk FUN_001268-T1 31 ADDLAAKVKQLEKELKSLRQQLKGK 55 678999****************965 PP == domain 2 score: 5.2 bits; conditional E-value: 0.033 DUF4600 53 esLkkllkqlekekrslenqlkdlelrleqeskAyhkvnder 94 ++L+ +kql++e rsl++ lk+ + l+ ++ + +++er FUN_001268-T1 171 DDLVDEVKQLKEELRSLHQLLKEKDN-LKSNEPPSKATEEER 211 67899999999999999999988653.333333334455555 PP >> DUF1192 Protein of unknown function (DUF1192) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.1 0.0023 2.4 13 49 .. 22 58 .. 16 61 .. 0.84 2 ? 1.2 0.2 0.53 5.7e+02 23 49 .. 171 197 .. 170 200 .. 0.87 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0023 DUF1192 13 igeDLslLSveELeerIalLeaEIaRleaaiakkkas 49 +++L + ++L++ +++Le+E l+++++ k++ FUN_001268-T1 22 SPKNLTSRRADDLAAKVKQLEKELKSLRQQLKGKDNL 58 56677777789**********************9875 PP == domain 2 score: 1.2 bits; conditional E-value: 0.53 DUF1192 23 eELeerIalLeaEIaRleaaiakkkas 49 ++L + +++L++E l + +++k++ FUN_001268-T1 171 DDLVDEVKQLKEELRSLHQLLKEKDNL 197 78999999*********9999999875 PP >> Spectrin_7 Animal spectrin repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.3 0.0088 9.3 2 27 .. 37 62 .. 31 106 .. 0.84 2 ? 5.7 0.5 0.024 25 3 27 .. 177 201 .. 169 234 .. 0.81 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0088 Spectrin_7 2 lakeLessfdsLeellkserdflnek 27 ++k+Le++++sL ++lk +++ ++++ FUN_001268-T1 37 KVKQLEKELKSLRQQLKGKDNLKSNE 62 5799*************998776644 PP == domain 2 score: 5.7 bits; conditional E-value: 0.024 Spectrin_7 3 akeLessfdsLeellkserdflnek 27 +k+L++++ sL +llk++++ ++++ FUN_001268-T1 177 VKQLKEELRSLHQLLKEKDNLKSNE 201 799**************98776643 PP >> OmpH Outer membrane protein (OmpH-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 1.2 0.00039 0.41 28 74 .. 31 81 .. 23 91 .. 0.70 2 ? 10.0 1.5 0.001 1.1 23 75 .. 165 221 .. 143 233 .. 0.79 3 ? -1.9 0.5 4.7 5e+03 37 51 .. 271 285 .. 251 314 .. 0.47 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00039 OmpH 28 fkkrqkelekkekelqklqeklq.aeaselsse....keekekelqkkeqel 74 ++++ ++++++ekel++l+++l+ +++ +s+e ++e+ + l +ke++l FUN_001268-T1 31 ADDLAAKVKQLEKELKSLRQQLKgKDN-LKSNEppskTTEEGRTLSTKEKAL 81 567788899999999999999986443.223333332455555599999987 PP == domain 2 score: 10.0 bits; conditional E-value: 0.001 OmpH 23 qlekefkkrqkelekkekelqklqeklqaeaselsse..keekeke..lqkkeqelq 75 +++++++++ +e++++++el++l + l+++ + +s+e +++ e+e l +ke++l FUN_001268-T1 165 TVNSKADDLVDEVKQLKEELRSLHQLLKEKDNLKSNEppSKATEEErtLSTKEKALT 221 67889999999****************954434443345444444445****99885 PP == domain 3 score: -1.9 bits; conditional E-value: 4.7 OmpH 37 kkekelqklqeklqa 51 +k+++ ++++k + FUN_001268-T1 271 TKKTAAANKEAKAAS 285 333333333333321 PP >> Nas2_N Nas2 N_terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.3 0.0062 6.6 2 32 .. 32 63 .. 31 71 .. 0.85 2 ? 4.8 0.4 0.034 37 2 30 .. 171 200 .. 170 206 .. 0.85 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0062 Nas2_N 2 keLqakkkeleaeleelsevLe.sqgvgmdtp 32 +L ak k+le+el++l + L+ +++++ ++p FUN_001268-T1 32 DDLAAKVKQLEKELKSLRQQLKgKDNLKSNEP 63 589999****************8888776665 PP == domain 2 score: 4.8 bits; conditional E-value: 0.034 Nas2_N 2 keLqakkkeleaeleelsevLe.sqgvgmd 30 +L+++ k+l++el++l++ L+ +++++ + FUN_001268-T1 171 DDLVDEVKQLKEELRSLHQLLKeKDNLKSN 200 5899999***************77777655 PP >> SlyX SlyX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.6 0.0066 7 31 64 .. 29 64 .. 27 64 .. 0.84 2 ? 5.5 0.4 0.035 37 32 64 .. 169 203 .. 162 211 .. 0.74 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0066 SlyX 31 reidrlqrqlrllaerlkeleesseasea..eeepP 64 r d l +++++l+++lk+l+++ +++++ +epP FUN_001268-T1 29 RRADDLAAKVKQLEKELKSLRQQLKGKDNlkSNEPP 64 6779999***************99988888666666 PP == domain 2 score: 5.5 bits; conditional E-value: 0.035 SlyX 32 eidrlqrqlrllaerlkeleesseasea..eeepP 64 + d l ++++l+e+l++l + +++++ +epP FUN_001268-T1 169 KADDLVDEVKQLKEELRSLHQLLKEKDNlkSNEPP 203 56778888888888888888877776666555555 PP >> Myo5a Unconventional myosin-Va domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 1.4 0.00013 0.13 18 58 .. 34 76 .. 33 112 .. 0.72 2 ? 8.6 6.6 0.0024 2.5 42 105 .. 141 204 .. 124 222 .. 0.70 3 ? -2.2 0.7 5.3 5.6e+03 54 54 .. 282 282 .. 250 312 .. 0.48 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00013 Myo5a 18 LqkrVreLEqerkklqselekkeeqeskkvk..eeekeselee 58 L +V++LE+e k+l+++l k++ +s++ ++e+ ++l++ FUN_001268-T1 34 LAAKVKQLEKELKSLRQQLKGKDNLKSNEPPskTTEEGRTLST 76 5679******************999887633002222233333 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0024 Myo5a 42 qeskkvkeeekeseleeeeeaelayeslkrqeLeseNkklkndLneLrkaladkaseensseea 105 ++kk+++++k + ++ ++ a+ + k +L +e k+lk++L++L++ l++k++ +++++ + FUN_001268-T1 141 ATTKKTTATNKVAKGALSNPVTHATVNSKADDLVDEVKQLKEELRSLHQLLKEKDNLKSNEPPS 204 3333333333444444555677788899*************************98766655544 PP == domain 3 score: -2.2 bits; conditional E-value: 5.3 Myo5a 54 s 54 + FUN_001268-T1 282 K 282 1 PP >> DUF6779 Domain of unknown function (DUF6779) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.2 0.006 6.4 64 88 .. 29 53 .. 19 70 .. 0.79 2 ? 6.8 1.0 0.014 15 58 90 .. 162 194 .. 124 212 .. 0.56 3 ? -0.5 0.2 2.5 2.6e+03 26 45 .. 276 295 .. 246 315 .. 0.49 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.006 DUF6779 64 aeveesaeelaalraeLaaLReqLe 88 +++++ a+++++l +eL++LR+qL+ FUN_001268-T1 29 RRADDLAAKVKQLEKELKSLRQQLK 53 444555778999**********997 PP == domain 2 score: 6.8 bits; conditional E-value: 0.014 DUF6779 58 veaelraeveesaeelaalraeLaaLReqLeeL 90 + a++++++++ +e+++l++eL++L + L+e FUN_001268-T1 162 THATVNSKADDLVDEVKQLKEELRSLHQLLKEK 194 233444444555679999*******99988874 PP == domain 3 score: -0.5 bits; conditional E-value: 2.5 DUF6779 26 aaeaeakaeeleevyelele 45 aa++eaka++ + v ++ ++ FUN_001268-T1 276 AANKEAKAASSNPVTHATVN 295 22222233222222222222 PP >> Ribosomal_L29 Ribosomal L29 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 2.6 0.0017 1.8 7 30 .. 30 53 .. 24 62 .. 0.84 2 ? 4.6 1.7 0.043 46 8 26 .. 170 188 .. 167 199 .. 0.87 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0017 Ribosomal_L29 7 sdeeLeeklkelkkeLfnLrfqka 30 ++L++k+k+l+keL Lr+q + FUN_001268-T1 30 RADDLAAKVKQLEKELKSLRQQLK 53 579*******************87 PP == domain 2 score: 4.6 bits; conditional E-value: 0.043 Ribosomal_L29 8 deeLeeklkelkkeLfnLr 26 ++L +++k+lk+eL L FUN_001268-T1 170 ADDLVDEVKQLKEELRSLH 188 699************9886 PP >> Fzo_mitofusin fzo-like conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.057 61 102 142 .. 19 59 .. 13 67 .. 0.76 2 ? 6.0 1.1 0.01 11 108 143 .. 164 199 .. 133 219 .. 0.88 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.057 Fzo_mitofusin 102 tfarLkqqvdetekeleeeikelekeieklekvqkrskllr 142 fa k+ + +l +++k+leke+++l + k l+ FUN_001268-T1 19 SFASPKNLTSRRADDLAAKVKQLEKELKSLRQQLKGKDNLK 59 56666667777788999999999999999988777766666 PP == domain 2 score: 6.0 bits; conditional E-value: 0.01 Fzo_mitofusin 108 qqvdetekeleeeikelekeieklekvqkrskllrn 143 ++v+ +l +e+k+l++e+++l ++ k+ l++ FUN_001268-T1 164 ATVNSKADDLVDEVKQLKEELRSLHQLLKEKDNLKS 199 6899999*******************9999999885 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 1.1 0.0022 2.4 28 50 .. 31 53 .. 28 61 .. 0.81 2 ? 4.2 2.1 0.062 66 34 56 .. 169 191 .. 164 201 .. 0.55 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0022 bZIP_1 28 ieeLerrvkaLekeNksLksele 50 + L+ +vk+Leke ksL+++l+ FUN_001268-T1 31 ADDLAAKVKQLEKELKSLRQQLK 53 57899999999999999999887 PP == domain 2 score: 4.2 bits; conditional E-value: 0.062 bZIP_1 34 rvkaLekeNksLkseleelkkev 56 +++ L e k+Lk+el +l FUN_001268-T1 169 KADDLVDEVKQLKEELRSLHQLL 191 55666666666666665544332 PP >> MerR_2 MerR HTH family regulatory protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.2 0.12 1.3e+02 67 84 .] 33 50 .. 31 50 .. 0.89 2 ? 6.4 0.3 0.0099 11 67 84 .] 172 189 .. 168 189 .. 0.91 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.12 MerR_2 67 dLLdrieqLqqevrsLrn 84 dL +++qL++e++sLr+ FUN_001268-T1 33 DLAAKVKQLEKELKSLRQ 50 67789***********97 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0099 MerR_2 67 dLLdrieqLqqevrsLrn 84 dL d+++qL++e+rsL + FUN_001268-T1 172 DLVDEVKQLKEELRSLHQ 189 8**************986 PP >> DUF7900 Domain of unknown function (DUF7900) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.4 0.0066 7 16 61 .. 37 82 .. 30 91 .. 0.87 2 ? 7.4 1.6 0.0089 9.5 15 61 .. 175 221 .. 167 244 .. 0.88 3 ? -2.3 0.1 9.5 1e+04 62 75 .. 297 310 .. 270 317 .. 0.61 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0066 DUF7900 16 eireleeelkklkeqkvsvskegesemlkkyeeenkkleeekkklv 61 ++++le elk l++q + ++e k ee + l ++k l+ FUN_001268-T1 37 KVKQLEKELKSLRQQLKGKDNLKSNEPPSKTTEEGRTLSTKEKALT 82 689***********99888888999999999999999998877765 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0089 DUF7900 15 deireleeelkklkeqkvsvskegesemlkkyeeenkkleeekkklv 61 de+++l+eel+ l++ ++ ++e k ee++ l ++k l+ FUN_001268-T1 175 DEVKQLKEELRSLHQLLKEKDNLKSNEPPSKATEEERTLSTKEKALT 221 999************99999999999999999999999998877765 PP == domain 3 score: -2.3 bits; conditional E-value: 9.5 DUF7900 62 eekkkleeeklkkl 75 +++k l ek + FUN_001268-T1 297 KDQKTLSTEKANQA 310 44444444444443 PP >> ZapB Cell division protein ZapB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.8 0.1 1.1e+02 29 48 .. 33 52 .. 24 84 .. 0.65 2 ? 8.5 2.8 0.0037 4 11 39 .. 168 196 .. 165 223 .. 0.73 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.1 ZapB 29 eLkekneelaeeaeeleeen 48 +L +k+++l++e++ l++++ FUN_001268-T1 33 DLAAKVKQLEKELKSLRQQL 52 33333344444333333333 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0037 ZapB 11 skiqaavdtielLkmeveeLkekneelae 39 sk + +vd++++Lk+e++ L + +e+++ FUN_001268-T1 168 SKADDLVDEVKQLKEELRSLHQLLKEKDN 196 78899*************99998877766 PP >> FapA Flagellar Assembly Protein A beta solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.9 0.0049 5.2 155 208 .. 28 81 .. 18 118 .. 0.68 2 ? 4.8 5.1 0.024 25 152 220 .. 164 231 .. 129 254 .. 0.65 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0049 FapA 155 kekleeleeelkeleeeleklkkklkklpk.kaekqldeekkeqleklletkekl 208 ++ ++l +++k+le+el+ l+++lk ++ k+ ++ +++ e+ + l ++ + l FUN_001268-T1 28 SRRADDLAAKVKQLEKELKSLRQQLKGKDNlKS-NEPPSKTTEEGRTLSTKEKAL 81 445588888899999999999998777777443.333444445544444444443 PP == domain 2 score: 4.8 bits; conditional E-value: 0.024 FapA 152 pelkekleeleeelkeleeeleklkkklkklpk.kaekqldeekkeqleklletkekleeeleeleeelk 220 ++++k ++l +e+k+l+eel+ l + lk+ ++ k+ + ++ k + e++l tkek + + +++ FUN_001268-T1 164 ATVNSKADDLVDEVKQLKEELRSLHQLLKEKDNlKS--NEPPSKATEEERTLSTKEKALTTSPSTPSKKN 231 456667777777777777777777777776666443..33566666666666666666555544444444 PP >> Spc24 Spc24 subunit of Ndc80 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.9 0.0063 6.7 11 43 .. 29 61 .. 22 103 .. 0.76 2 ? 3.5 3.4 0.11 1.1e+02 10 44 .. 167 204 .. 162 222 .. 0.68 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0063 Spc24 11 kelsdleselerleselaklkeeleeleeeeve 43 + ++dl +++++le+el++l+++l+ ++ +++ FUN_001268-T1 29 RRADDLAAKVKQLEKELKSLRQQLKGKDNLKSN 61 667889999999999999999998866666555 PP == domain 2 score: 3.5 bits; conditional E-value: 0.11 Spc24 10 akelsdleselerleselaklkeeleeleeeeve...e 44 + +++dl +e+++l++el++l++ l+e ++ +++ + FUN_001268-T1 167 NSKADDLVDEVKQLKEELRSLHQLLKEKDNLKSNeppS 204 56788888999999999999998888887777775431 PP >> Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.3 0.0083 8.8 68 91 .. 30 53 .. 17 87 .. 0.76 2 ? 8.4 3.2 0.0033 3.5 36 94 .. 137 195 .. 125 200 .. 0.72 3 ? -2.1 0.5 5.9 6.2e+03 45 65 .. 275 295 .. 254 315 .. 0.50 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0083 Seryl_tRNA_N 68 daeeliaevkelkeelkaleeelk 91 a++l a+vk+l +elk l ++lk FUN_001268-T1 30 RADDLAAKVKQLEKELKSLRQQLK 53 456666666666666666666665 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0033 Seryl_tRNA_N 36 ekrrelqveleelqa.erNelskeIgkakkkkedaeeliaevkelkeelkaleeelkele 94 +k ++ +++ + ++ + +ls+ + a + +a++l++evk+lkeel l + lke + FUN_001268-T1 137 KKTTATTKKTTATNKvAKGALSNPVTHATVNS-KADDLVDEVKQLKEELRSLHQLLKEKD 195 55555555555444414557888888888875.99*****************99999876 PP == domain 3 score: -2.1 bits; conditional E-value: 5.9 Seryl_tRNA_N 45 leelqaerNelskeIgkakkk 65 + + ++ + + s+ + a + FUN_001268-T1 275 AAANKEAKAASSNPVTHATVN 295 223333333333333333333 PP >> DUF7365 Coiled-coil region of unknown function (DUF7365) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.12 1.3e+02 37 95 .. 33 53 .. 7 61 .. 0.69 2 ? 6.7 1.1 0.01 11 30 96 .. 127 193 .. 119 198 .. 0.83 3 ? -1.2 0.1 3 3.2e+03 16 36 .. 330 347 .. 323 356 .. 0.63 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.12 DUF7365 37 klehritkLevkveelekviksharRLdkhdeqqkallalveqvknLsedvrelkkdik 95 + l+ +vk+L ++++ l++++k FUN_001268-T1 33 D--------------------------------------LAAKVKQLEKELKSLRQQLK 53 4......................................45566666666666666555 PP == domain 2 score: 6.7 bits; conditional E-value: 0.01 DUF7365 30 sskakaaklehritkLevkveelekviksharRLdkhdeqqkallalveqvknLsedvrelkkdike 96 ss +k++ ++ t+ +k +kv+k + + h+ + lv+ vk+L e++r l + +ke FUN_001268-T1 127 SSSDKTTATTKKTTATTKKTTATNKVAKGALSNPVTHATVNSKADDLVDEVKQLKEELRSLHQLLKE 193 5667777778888888888888888888888888889999999999******************998 PP == domain 3 score: -1.2 bits; conditional E-value: 3 DUF7365 16 vvlpiaisvlglyvsskakaa 36 v + + v+++y++ +++ + FUN_001268-T1 330 V---LLVIVVVTYMIYHNRNK 347 2...33446677777776655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (387 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3658 (0.143198); expected 510.9 (0.02) Passed bias filter: 1215 (0.0475631); expected 510.9 (0.02) Passed Vit filter: 186 (0.00728127); expected 25.5 (0.001) Passed Fwd filter: 64 (0.00250538); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 24 [number of targets reported over threshold] # CPU time: 0.47u 0.46s 00:00:00.93 Elapsed: 00:00:00.42 # Mc/sec: 3708.69 // Query: FUN_001269-T1 [L=622] Description: FUN_001269 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-19 68.3 13.1 1.2e-18 67.5 13.1 1.5 1 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domai ------ inclusion threshold ------ 0.15 12.5 0.2 0.34 11.5 0.2 1.5 1 DUF5490 Family of unknown function (DUF5490) Domain annotation for each model (and alignments): >> Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.5 13.1 9.5e-23 1.2e-18 1 53 [] 49 101 .. 49 101 .. 0.98 Alignments for each domain: == domain 1 score: 67.5 bits; conditional E-value: 9.5e-23 Kunitz_BPTI 1 vCslpkdsGpCkasvkryyydaetkkCeeFvYgGcgGneNnFeskeeCesaCk 53 +C lp+++GpC+a +++++++++t+kCe+F+YgGc+Gn+NnFe++++C ++Ck FUN_001269-T1 49 FCYLPPKTGPCRAAFRNWFFNNKTSKCEQFIYGGCKGNQNNFETEANCTDTCK 101 6***************************************************6 PP >> DUF5490 Family of unknown function (DUF5490) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.2 2.6e-05 0.34 25 46 .. 56 77 .. 39 82 .. 0.76 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 2.6e-05 DUF5490 25 nGiedevflnwfwnnkyaaceG 46 G f nwf+nnk + ce FUN_001269-T1 56 TGPCRAAFRNWFFNNKTSKCEQ 77 555566899***********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (622 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 570 (0.0223136); expected 510.9 (0.02) Passed bias filter: 317 (0.0124095); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.41s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5976.91 // Query: FUN_001269-T2 [L=644] Description: FUN_001269 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-19 68.3 13.1 1.3e-18 67.4 13.1 1.5 1 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domai 0.0003 21.5 11.8 0.00049 20.8 5.7 3.2 2 KCT2 Keratinocyte-associated gene product ------ inclusion threshold ------ 0.16 12.5 0.2 0.35 11.4 0.2 1.5 1 DUF5490 Family of unknown function (DUF5490) Domain annotation for each model (and alignments): >> Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.4 13.1 1.5e-22 1.3e-18 1 53 [] 49 101 .. 49 101 .. 0.98 Alignments for each domain: == domain 1 score: 67.4 bits; conditional E-value: 1.5e-22 Kunitz_BPTI 1 vCslpkdsGpCkasvkryyydaetkkCeeFvYgGcgGneNnFeskeeCesaCk 53 +C lp+++GpC+a +++++++++t+kCe+F+YgGc+Gn+NnFe++++C ++Ck FUN_001269-T2 49 FCYLPPKTGPCRAAFRNWFFNNKTSKCEQFIYGGCKGNQNNFETEANCTDTCK 101 6***************************************************6 PP >> KCT2 Keratinocyte-associated gene product # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.4 0.034 2.9e+02 62 120 .. 196 255 .. 164 258 .. 0.72 2 ! 20.8 5.7 5.7e-08 0.00049 90 183 .. 550 636 .. 479 641 .. 0.79 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.034 KCT2 62 akdtldnGdyGepdydwttsprd.eesdeile..enreykeleesvksvkvpaseveeedsh 120 ++l n + G+p d+ ++ d e+ +++ + e+++ e+ ++vk+v ++++v++ed h FUN_001269-T2 196 SGESLSNHEDGQPRNDLPRKNGDgEDGHKVENvtEKNGDGEVGHKVKGV--TGKNVDDEDGH 255 4578999999999999999988866666554411444556778888876..57888899999 PP == domain 2 score: 20.8 bits; conditional E-value: 5.7e-08 KCT2 90 ileenreykeleesvksvkvpaseveeedshfffhliifafcvavvyvtyhnkrkifllvqsrkwrdGlcsktveyhrldqnvneampslkitn 183 + nr+ l+++ +v + e+ shf ++ +v vy +yhn++ki ++ + + s +l+ nv+eamp++k t FUN_001269-T2 550 EENVNRGNYRLKQRKSGVYGDSDSYEHTSSHFAGFFLTSIVMVFAVYAVYHNRQKIVAIIIEGR--NDNRS-----RKLETNVEEAMPAMKNTH 636 3466888889999999999999999******976666666677789**********98776543..33344.....57899**********985 PP >> DUF5490 Family of unknown function (DUF5490) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.2 4.1e-05 0.35 25 46 .. 56 77 .. 39 82 .. 0.76 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 4.1e-05 DUF5490 25 nGiedevflnwfwnnkyaaceG 46 G f nwf+nnk + ce FUN_001269-T2 56 TGPCRAAFRNWFFNNKTSKCEQ 77 555566899***********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (644 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 842 (0.0329614); expected 510.9 (0.02) Passed bias filter: 510 (0.0199648); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6118.14 // Query: FUN_001269-T3 [L=565] Description: FUN_001269 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-19 68.5 13.1 1.1e-18 67.7 13.1 1.5 1 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domai ------ inclusion threshold ------ 0.14 12.7 0.2 0.3 11.6 0.2 1.5 1 DUF5490 Family of unknown function (DUF5490) Domain annotation for each model (and alignments): >> Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.7 13.1 8.4e-23 1.1e-18 1 53 [] 49 101 .. 49 101 .. 0.98 Alignments for each domain: == domain 1 score: 67.7 bits; conditional E-value: 8.4e-23 Kunitz_BPTI 1 vCslpkdsGpCkasvkryyydaetkkCeeFvYgGcgGneNnFeskeeCesaCk 53 +C lp+++GpC+a +++++++++t+kCe+F+YgGc+Gn+NnFe++++C ++Ck FUN_001269-T3 49 FCYLPPKTGPCRAAFRNWFFNNKTSKCEQFIYGGCKGNQNNFETEANCTDTCK 101 6***************************************************6 PP >> DUF5490 Family of unknown function (DUF5490) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.2 2.4e-05 0.3 25 46 .. 56 77 .. 39 82 .. 0.76 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.4e-05 DUF5490 25 nGiedevflnwfwnnkyaaceG 46 G f nwf+nnk + ce FUN_001269-T3 56 TGPCRAAFRNWFFNNKTSKCEQ 77 555566899***********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (565 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 487 (0.0190644); expected 510.9 (0.02) Passed bias filter: 234 (0.00916031); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 5393.01 // Query: FUN_001270-T1 [L=350] Description: FUN_001270 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-38 132.7 0.4 3.9e-38 132.3 0.4 1.1 1 Cupin_8 Cupin-like domain 3e-08 33.8 0.0 8e-08 32.4 0.0 1.7 1 JmjC_2 JmjC domain 0.003 18.5 0.3 0.16 12.9 0.1 2.6 2 JmjC JmjC domain, hydroxylase ------ inclusion threshold ------ 0.064 13.5 0.0 0.23 11.7 0.0 1.8 2 Cupin_2 Cupin domain 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 ERAP1_C ERAP1-like C-terminal domain Domain annotation for each model (and alignments): >> Cupin_8 Cupin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.3 0.4 7.6e-42 3.9e-38 6 248 .. 42 287 .. 38 290 .. 0.80 Alignments for each domain: == domain 1 score: 132.3 bits; conditional E-value: 7.6e-42 Cupin_8 6 reyvaknkPvvikgavkdwpavekwkdkeelldylkekagdvkvsveetpdgradalfenddltfvnpk......eeemtfkeflkeleaesdqka 95 ++++a ++Pv++ + + + kw+ ldylk+ g +sv+ ++ + +++++++ + p + m+f+ef +++++ + + FUN_001270-T1 42 ESIIANEEPVLLVNS-NIISSALKWD-----LDYLKKNLGAGSFSVYSSKT--CKFMYYDEKRAKQWPYfipptqRIHMKFEEFCSRVRNLK--AT 127 678999********9.77777889*8.....5******9999999977763..23333333322222212222337789***********96..55 PP Cupin_8 96 ekalylqsaslrsefpelked...ndlplateafgeepkavn........lWiGnersvtslHkDhyeNlycvvrGrKrFtLfpPsdvenLyegpl 180 ++++ylq++ +s +++ +d ++ ++ te+ + ++n l iG + +t +H+D +N++ ++ G Kr++Lf P+++++Ly+ pl FUN_001270-T1 128 DSRVYLQQMLDDSVGKNIVKDfleFKWQWLTEMQR----KMNwgsltsnlLLIGLPGNITPVHYDEQQNFFGQLTGFKRVILFHPDQFKCLYPFPL 219 5799**98888888888888875555556555543....3333334444599*******************************************9 PP Cupin_8 181 eepegqsvslvdvdapdlekfprfreaakalevelepGdvLylPalWfHhVesl..dplniavnyWydms 248 + p s+vd+d+pd+++fp+++e k +ev++ pGdvLy+P +W+HhVes+ ++++ +vn+W+++ FUN_001270-T1 220 YHP-CDRQSQVDFDNPDFKRFPKLKEL-KGYEVIVGPGDVLYIPMYWWHHVESTmnSGVTTSVNFWFKAG 287 995.45689******************.*************************98899*********976 PP >> JmjC_2 JmjC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 0.0 1.6e-11 8e-08 33 119 .. 179 282 .. 147 287 .. 0.76 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 1.6e-11 JmjC_2 33 ggsegvgpHyDeydvfilQleGkkrWrvgk..............pkeeeqeek.seeelklldefepve..dlvLepGDlLYlPrgliHqgvaee. 110 +g + + HyDe f Ql+G kr + + p++++++ + +++++k++ + + + ++++ pGD+LY+P ++H+ ++ FUN_001270-T1 179 PG-NITPVHYDEQQNFFGQLTGFKRVILFHpdqfkclypfplyhPCDRQSQVDfDNPDFKRFPKLKELKgyEVIVGPGDVLYIPMYWWHHVESTMn 273 44.46788********************99999*******888877766665425667888887755544699*****************998887 PP JmjC_2 111 esltlsvgl 119 +++t sv + FUN_001270-T1 274 SGVTTSVNF 282 899999986 PP >> JmjC JmjC domain, hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.037 1.9e+02 23 56 .. 90 125 .. 68 146 .. 0.68 2 ! 12.9 0.1 3.1e-05 0.16 76 114 .] 243 282 .. 173 282 .. 0.75 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.037 JmjC 23 inylhfgapkvWyiipeekkekle..kvlkkenske 56 + y+ +a++++y+ip+ ++ +++ +++++ + + FUN_001270-T1 90 MYYDEKRAKQWPYFIPPTQRIHMKfeEFCSRVRNLK 125 667788888899*****9986554448888873333 PP == domain 2 score: 12.9 bits; conditional E-value: 3.1e-05 JmjC 76 egipvyrivqkpgefVivfpgayHavfn.lgfniaeavnf 114 ++ + y++ pg++++++ +++H v + + + + ++vnf FUN_001270-T1 243 KELKGYEVIVGPGDVLYIPMYWWHHVEStMNSGVTTSVNF 282 34789*******************9865145566666666 PP >> Cupin_2 Cupin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.93 4.7e+03 7 22 .. 179 194 .. 178 199 .. 0.83 2 ? 11.7 0.0 4.5e-05 0.23 33 59 .. 245 271 .. 241 278 .. 0.87 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.93 Cupin_2 7 pGesspehrHpgeeff 22 pG +p h+ +++ ff FUN_001270-T1 179 PGNITPVHYDEQQNFF 194 7888999**9999877 PP == domain 2 score: 11.7 bits; conditional E-value: 4.5e-05 Cupin_2 33 vdgeevvlkaGdsvyfpagvpHrfrNt 59 + g ev++++Gd++y+p +H+++ t FUN_001270-T1 245 LKGYEVIVGPGDVLYIPMYWWHHVEST 271 67889******************9876 PP >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 4.7e-05 0.24 228 308 .. 122 203 .. 106 205 .. 0.82 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 4.7e-05 ERAP1_C 228 devrnqdlravlaglasnpagrelawdfvkenwdelekrlgg.gs.sl.grlvkgltpsfsteeeldeveaFfadkdtpglrra 308 +++ d+r l+++ ++g+ ++ df++ +w+ l ++ ++ + sl ++l+ +p+ t+ ++de ++Ff + g++r+ FUN_001270-T1 122 RNLKATDSRVYLQQMLDDSVGKNIVKDFLEFKWQWLTEMQRKmNWgSLtSNLLLIGLPGNITPVHYDEQQNFFGQL--TGFKRV 203 468999*********999********************76643223445*********999************775..566665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (350 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 557 (0.0218047); expected 510.9 (0.02) Passed bias filter: 481 (0.0188295); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3555.17 // Query: FUN_001271-T1 [L=736] Description: FUN_001271 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-71 241.5 0.0 1.8e-70 237.8 0.0 2.2 2 Pkinase Protein kinase domain 2.3e-36 124.1 0.4 1e-16 61.1 0.1 3.0 3 cNMP_binding Cyclic nucleotide-binding domain 3.1e-34 119.0 0.0 6.7e-34 117.8 0.0 1.5 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.001 18.8 0.0 0.0032 17.3 0.0 1.8 1 Kinase-like Kinase-like ------ inclusion threshold ------ 0.021 14.5 0.0 0.037 13.7 0.0 1.3 1 ABC1 ABC1 atypical kinase-like domain 0.032 13.8 0.0 0.29 10.6 0.0 2.1 2 Seadorna_VP7 Seadornavirus VP7 0.041 14.0 0.1 1.1 9.4 0.0 2.4 2 FTA2 Kinetochore Sim4 complex subunit FTA2 0.2 11.8 0.9 0.34 11.1 0.0 1.8 2 APH Phosphotransferase enzyme family 0.22 11.7 0.0 3.2 7.9 0.0 2.4 2 Choline_kin_N Choline kinase N terminus 0.35 11.6 9.8 0.69 10.6 9.8 1.4 1 GAGA_bind GAGA binding protein-like family Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.11 2.8e+02 31 73 .. 132 177 .. 116 203 .. 0.75 2 ! 237.8 0.0 7.2e-74 1.8e-70 2 262 .] 428 685 .. 427 685 .. 0.97 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.11 Pkinase 31 kikkekakkkke...kkvlrEikilkklkhpnivrlidvfeekdel 73 +++++ ++ +++ k++++E ++lk+l++ ++ +++d+++ k+++ FUN_001271-T1 132 ELERHPKDFRSKqliKDAINENDFLKNLESAQVREIVDCMYPKTYF 177 45444333333336799****************9999999887665 PP == domain 2 score: 237.8 bits; conditional E-value: 7.2e-74 Pkinase 2 evleklGeGsfgkVykaveketgkivAiKkikkekakkkke.kkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgals 96 ev+ +lG G+fg+V ++ +++++++A+K++kk+++ ++++ +++ +E ki+++ ++p+i++l+++f++ +++y++lE++ ggel+++l+++g+++ FUN_001271-T1 428 EVIATLGIGGFGRVELVQTTKDKHTYALKCLKKKHIIDTRQqEHIHSEKKIMSQANSPFICKLYRTFKDRKYVYMLLELCLGGELWSILRDRGCFD 523 67789******************************9998888****************************************************** PP Pkinase 97 eeeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYmAPEvlkskkygkkvDvWslGvilyellt 192 +++ +++++ ++e+leylHs+g+v+rDlKpeN+L++++g +K++DFG+ak++ + k+ +f+gt+eY+APE++ +k+++ ++D WslG++++ellt FUN_001271-T1 524 DSTSRFFVACVVEALEYLHSRGIVYRDLKPENLLLNKDGYIKLVDFGFAKRIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADCWSLGILIFELLT 619 ************************************************************************************************ PP Pkinase 193 gkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRlt.....aeellqhpwf 262 g+ppf+a++ ++++ +l+ + +++p++i ++ ++l+++l+++ p++Rl+ + ++++h+wf FUN_001271-T1 620 GSPPFYASDPMKTYNIILRG---------MDVMEFPKKIGRNPQNLIRRLCRESPTERLGyqkdgLADVKNHKWF 685 ***********999999999.........4567899************************888888899999998 PP >> cNMP_binding Cyclic nucleotide-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.8 0.0 1e-19 2.6e-16 2 88 .. 174 255 .. 173 256 .. 0.93 2 ! 61.1 0.1 4.1e-20 1e-16 2 86 .. 292 378 .. 291 380 .. 0.91 3 ? -1.5 0.0 1.4 3.6e+03 26 48 .. 439 461 .. 438 466 .. 0.83 Alignments for each domain: == domain 1 score: 59.8 bits; conditional E-value: 1e-19 cNMP_binding 2 rsfkagevifregdpadslyivlsGkvkvyrttedGkeqilavlgpGdffGelallggeprsatvvAledsellvipredfleller 88 +++ +g++i++egd++ ly++ +G+v+v t+d ++l+ ++ G++fGela+l + +r+atv A+ +++l+ i+r+ f+ +++r FUN_001271-T1 174 KTYFKGDIIVQEGDTGHALYVIAEGCVEV---TKDC--EFLGQMRGGAVFGELAILYNCKRTATVKAINNAKLWIIDRSVFQMIMMR 255 57889************************...3455..49****************99************************99986 PP == domain 2 score: 61.1 bits; conditional E-value: 4.1e-20 cNMP_binding 2 rsfkagevifregdpadslyivlsGkvkvy.rttedGkeqilavlgpGdffGelallggeprsatvvAled.sellvipredflell 86 +++ ++i+reg+++d +yi+ +G+v v+ +t + q +++l++Gd+fGe all + +r+a+v+A+++ +e+lv++r +f++l+ FUN_001271-T1 292 EYYHGEDFIIREGETGDTFYIINKGSVIVTqAVTGYDDPQEVRRLQRGDYFGEKALLSEYRRTANVIAETPgVECLVVERTAFNALI 378 5688899*********************973455555679*****************9999***********************997 PP == domain 3 score: -1.5 bits; conditional E-value: 1.4 cNMP_binding 26 GkvkvyrttedGkeqilavlgpG 48 G+v++++tt+d+ + l+ l++ FUN_001271-T1 439 GRVELVQTTKDKHTYALKCLKKK 461 99*********999888887765 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 117.8 0.0 2.6e-37 6.7e-34 2 249 .. 428 669 .. 427 673 .. 0.93 Alignments for each domain: == domain 1 score: 117.8 bits; conditional E-value: 2.6e-37 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtlkeea..seeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrk 94 e+ +lG G fG+V + + k+k + a+K+lk+++ + +++e++ +e k+m++ + p i+kl+ +++ +++++e++ gG+L ++Lr+ FUN_001271-T1 428 EVIATLGIGGFGRVELVQTT----KDKHTYALKCLKKKHiiDTRQQEHIHSEKKIMSQANSPFICKLYRTFKDRKYVYMLLELCLGGELWSILRD 518 67789**********99999....8888999999977652367779999*********************************************9 PP PK_Tyr_Ser-Thr 95 kkeklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDvWs 189 + ++ ++ +++ + +++eyL+s+ +v rdl N L++++ +k+ DfG a+ + +k+ + +++apE++ +k ++D Ws FUN_001271-T1 519 -RGCFDDSTSRFFVACVVEALEYLHSRGIVYRDLKPENLLLNKDGYIKLVDFGFAKRI---GFGRKTWTFCGTPEYVAPEIILNKGHDLSADCWS 609 .689999999999999******************************************...6778888888899********************* PP PK_Tyr_Ser-Thr 190 fGvllwEiftlgeepykglkneevlell.eegerleqpencpeelyelmkeCweedpeeRp 249 G+l++E++t g+ p+ ++ ++++ + + +e p+++ ++ ++l+++ ++e+p+eR FUN_001271-T1 610 LGILIFELLT-GSPPFYASDPMKTYNIIlRGMDVMEFPKKIGRNPQNLIRRLCRESPTERL 669 **********.****************95666779************************97 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 1.3e-06 0.0032 148 263 .. 529 636 .. 508 668 .. 0.68 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 1.3e-06 Kinase-like 148 lllTlqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvv.seve..kgfaPpEllgsrgglytrknktlmtfkldaWqlGlv 240 + ++ +L+s g+v +++++nlll++ g ++l +f+ r g + + + + pE+ ++ + d W lG+ FUN_001271-T1 529 FFVAC-VVEALEYLHSRGIVYRDLKPENLLLNKDGYIKLVDFGFAKRIGFGRKtWTFCgtPEYVAPEIILNK----------GHDLSADCWSLGIL 613 44444.788899******************************999888865442333322233344444332..........2356789******* PP Kinase-like 241 IysiwclklPltlvaeeakeewi 263 I+ + P+ + + i FUN_001271-T1 614 IFELLTGSPPFYASDPMKTYNII 636 **999888888777776666663 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 1.5e-05 0.037 181 219 .. 538 576 .. 500 584 .. 0.84 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.5e-05 ABC1 181 leqifedgffhaDphpGNllvrkdgelvllDfGlmgeld 219 le + g++ D+ p Nll++kdg + l+DfG +++ FUN_001271-T1 538 LEYLHSRGIVYRDLKPENLLLNKDGYIKLVDFGFAKRIG 576 566778899*************************99985 PP >> Seadorna_VP7 Seadornavirus VP7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.15 3.9e+02 176 233 .. 227 285 .. 214 305 .. 0.70 2 ? 10.6 0.0 0.00011 0.29 149 187 .. 533 569 .. 520 572 .. 0.83 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.15 Seadorna_VP7 176 cDklGmlklvDPasL..lsqtvvyvnteYkdltvddevksfllsllelvanlrkieseki 233 c ++ ++k ++ a L +++ v + + +++t ++e +fl+s+ l +nl + e +k+ FUN_001271-T1 227 CKRTATVKAINNAKLwiIDRSVFQMIMMRTGMTRQAEHVAFLKSV-PLLKNLSDQEFSKL 285 556666677776665436777777778888999999999999985.45555555555555 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00011 Seadorna_VP7 149 aGlksLmdlhresggtlhGDvnvenlmcDklGmlklvDP 187 +++L lh s g+++ D ++enl+ +k G++klvD FUN_001271-T1 533 CVVEALEYLH--SRGIVYRDLKPENLLLNKDGYIKLVDF 569 3467899999..899**********************95 PP >> FTA2 Kinetochore Sim4 complex subunit FTA2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.081 2.1e+02 24 85 .. 427 485 .. 417 494 .. 0.59 2 ? 9.4 0.0 0.00043 1.1 181 213 .. 535 572 .. 512 573 .. 0.82 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.081 FTA2 24 iefleyLgeglhsvVvkvki..rgkeYAlKlFrfveaeeleeeaeedlktpqeslkeladysdp 85 e + Lg g ++V v+ ++++YAlK ++ + +++ ++e ++ k +++ +p FUN_001271-T1 427 LEVIATLGIGGFGRVELVQTtkDKHTYALKCLKKKHIIDTR--QQE---HIHSEKKIMSQANSP 485 5666777666666665555411567*****99888664443..333...333344444444455 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00043 FTA2 181 lrdlkklhklgIvvrDlkeenyi...dg..klvDlsra 213 + l+ lh+ gIv+rDlk+en++ dg klvD++ a FUN_001271-T1 535 VEALEYLHSRGIVYRDLKPENLLlnkDGyiKLVDFGFA 572 678999***************99544445569999876 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.3 3.8 9.8e+03 121 154 .. 15 43 .. 9 58 .. 0.54 2 ? 11.1 0.0 0.00013 0.34 167 198 .. 543 573 .. 510 575 .. 0.81 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 3.8 APH 121 larrlellrqleaaaarllaaelkdrleeleeql 154 +++++ll++++a+++r l+++++ +++ FUN_001271-T1 15 AEQDGKLLPKRTAQLKRELKEKDDF-----LQRK 43 4566666666777754444443333.....3322 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00013 APH 167 ppvlvHgDlhpgNllvddggrvsGviDFedag 198 +++v +Dl+p Nll++ ++ ++DF++a FUN_001271-T1 543 SRGIVYRDLKPENLLLN-KDGYIKLVDFGFAK 573 589**************.444448*****985 PP >> Choline_kin_N Choline kinase N terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.0 0.0013 3.2 9 31 .. 160 182 .. 157 183 .. 0.89 2 ? 0.5 0.0 0.26 6.6e+02 31 47 .. 427 443 .. 414 446 .. 0.90 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0013 Choline_kin_N 9 lvpsvkaplDislPsdyFKqdil 31 ++++v+ + D++ P yFK di+ FUN_001271-T1 160 ESAQVREIVDCMYPKTYFKGDII 182 678999999*************8 PP == domain 2 score: 0.5 bits; conditional E-value: 0.26 Choline_kin_N 31 lrllhtLaiskWgdvpl 47 l++++tL i + g+v+l FUN_001271-T1 427 LEVIATLGIGGFGRVEL 443 79*************87 PP >> GAGA_bind GAGA binding protein-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 9.8 0.00027 0.69 28 148 .. 26 148 .. 6 173 .. 0.64 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00027 GAGA_bind 28 glqlmsilaeRdalleernlvlalsekkealaerdmaflrrdaalaerdkallerdnalaalqmlrp....kehqlqeaes.palekeevasseal 118 ql l+e+d++l+++++ l+ ++ + e+dm++++ + ++e + + + ++++ l m+++ + +l++ + ++ +++e+ ++ FUN_001271-T1 26 TAQLKRELKEKDDFLQRKEA--ELQYRQLVIDEKDMELTKLRKEIHELKCVVQQTARKSSVLSMIQEdremAAVNLKSGTKdTSSSRKEKRMAVSG 119 468999999*******9998..668889999****************9999999999999999999633221111122221022233333322233 PP GAGA_bind 119 eesavvkeaakkrqkkkrpkepkakkakks 148 e+s+ ++e++ k++ +++pk+ ++k+ k FUN_001271-T1 120 ESSSKAQENT-KKELERHPKDFRSKQLIKD 148 3333333333.3334466666666555542 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (736 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1534 (0.0600509); expected 510.9 (0.02) Passed bias filter: 655 (0.025641); expected 510.9 (0.02) Passed Vit filter: 78 (0.00305344); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.40u 0.43s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 7080.26 // Query: FUN_001272-T1 [L=119] Description: FUN_001272 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-44 151.4 0.8 1.5e-44 151.1 0.8 1.0 1 eIF_4EBP Eukaryotic translation initiation factor 4E binding Domain annotation for each model (and alignments): >> eIF_4EBP Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 151.1 0.8 5.8e-49 1.5e-44 8 117 .] 10 119 .] 3 119 .] 0.95 Alignments for each domain: == domain 1 score: 151.1 bits; conditional E-value: 5.8e-49 eIF_4EBP 8 qteskaiptrrvlikdasqlPedysttpGGtlfsttPGgtriiYdrkfLlelrnSPlaktPPsnlpkiPgvtskekkkekkekekkeaekkeekee 103 +es+aip+rrv+++d+ qlP d sttpGGt+fsttPGgtriiY+rkfLlelrnSPl++tPP+nlp iPgvt+++k+k +++k + ++++e+++ FUN_001272-T1 10 PSESRAIPSRRVVLNDPGQLPIDCSTTPGGTIFSTTPGGTRIIYERKFLLELRNSPLSRTPPQNLPLIPGVTCDKKAKPASPKDNGVPTTHAENDK 105 589***********************************************************************999999999999999999**** PP eIF_4EBP 104 kekkeeeeqfemdi 117 +e ++ee qfem+i FUN_001272-T1 106 NEVDQEEPQFEMEI 119 ************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 303 (0.0118614); expected 510.9 (0.02) Passed bias filter: 225 (0.00880799); expected 510.9 (0.02) Passed Vit filter: 12 (0.000469759); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1223.99 // Query: FUN_001274-T1 [L=796] Description: FUN_001274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-15 56.7 18.2 5.6e-10 39.8 3.1 3.4 3 DED Death effector domain 0.0042 17.4 0.6 0.11 12.9 1.1 2.7 2 Lectin_N Hepatic lectin, N-terminal domain ------ inclusion threshold ------ 0.19 12.3 0.0 7.5 7.2 0.0 3.2 3 DUF4752 Domain of unknown function (DUF4752) 0.2 12.3 0.5 0.95 10.1 0.2 2.2 2 DUF4313 Domain of unknown function (DUF4313) 0.7 10.9 4.7 9.7 7.2 0.1 4.4 5 DUF3067 Domain of unknown function (DUF3067) 0.95 10.5 7.8 0.57 11.2 1.9 2.7 2 Kri1 KRI1-like family 1.6 9.5 6.6 25 5.6 0.3 3.9 4 BORCS6 BLOC-1-related complex sub-unit 6 C-terminal he 2.5 8.9 12.5 0.32 11.8 1.1 3.6 4 MutS_III MutS domain III 5.4 7.3 7.7 3.2 8.0 0.1 3.1 3 Leptin Leptin Domain annotation for each model (and alignments): >> DED Death effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.8 3.1 2e-13 5.6e-10 1 81 [. 6 87 .. 6 88 .. 0.97 2 ! 25.8 2.2 4.8e-09 1.4e-05 26 81 .. 120 175 .. 94 176 .. 0.85 3 ? -2.6 0.2 3.3 9.3e+03 60 75 .. 611 625 .. 589 633 .. 0.54 Alignments for each domain: == domain 1 score: 39.8 bits; conditional E-value: 2e-13 DED 1 frklLleiseeLts.eelesLkFLlkdkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +++lL++is++L++ +le++ F ++ k+ ++ ++i++ l+l++ Le+ + l+ d l+l++++L+ + dL +k+ k+++ FUN_001274-T1 6 YNSLLFRISKRLDNiNDLEHILFICRGKLEHQADQDINNTLSLLRKLEDCNFLGVDYLQLVKDILKAVEEWDLHEKVVKFER 87 789*********98689**************************************************************997 PP == domain 2 score: 25.8 bits; conditional E-value: 4.8e-09 DED 26 dkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +ip+++ ++++++++l++ Le+++ l+ d l++L+e+L +++ ++Ll+++++++k FUN_001274-T1 120 RRIPEERRNDVHDVRSLVQVLEEKNSLGIDCLEILREILTELNDDELLSELSEFQK 175 479**************************************************987 PP == domain 3 score: -2.6 bits; conditional E-value: 3.3 DED 60 LeelLrrikrkdLlkk 75 +ee L++++ + L k+ FUN_001274-T1 611 IEEKLKKVNAN-LQKQ 625 34444444444.4444 PP >> Lectin_N Hepatic lectin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.22 6.3e+02 4 54 .. 172 228 .. 169 238 .. 0.80 2 ! 12.9 1.1 3.7e-05 0.11 64 122 .. 581 639 .. 551 650 .. 0.86 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.22 Lectin_N 4 dlQqldsEekdhqlrkg.....apppqsllqrlcsklrllllslgls.llLLvvvcv 54 ++Q+ E+++++ rk ++++++ +qr++ + rl ++s ++LLv + FUN_001274-T1 172 EFQKRRIEDETQERRKAreaavWSSARAATQRIIGEIRLRCTFRTVSgVVLLVGTGL 228 7899999999988888888888899999*******9999887766654778887655 PP == domain 2 score: 12.9 bits; conditional E-value: 3.7e-05 Lectin_N 64 eeletLketfsNfssstlaevqalssqggslgdkvtsleaklekkqqdlkadhselllh 122 ++ tLk + ++ + +q+l+ + ++++k++ ++a+l+k+ ++l+ad s + + FUN_001274-T1 581 SDEPTLKRFLPKSLTTGIQRLQELRKRKTEIEEKLKKVNANLQKQMKKLEADTSRAVDE 639 555677777766667777899********************************987655 PP >> DUF4752 Domain of unknown function (DUF4752) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.38 1.1e+03 44 78 .. 232 266 .. 230 271 .. 0.86 2 ? 7.2 0.0 0.0027 7.5 28 69 .. 270 311 .. 266 315 .. 0.91 3 ? -1.1 0.0 1 2.9e+03 47 61 .. 414 428 .. 405 430 .. 0.83 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.38 DUF4752 44 rqkAlnafydaFdldslepGstirvatkgdlvili 78 r ++f +aF + l +++r +++g + ++ FUN_001274-T1 232 RCFTFDDFVQAFTVAILPASNVLRAISEGSVCFMV 266 5667899*********************9998876 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0027 DUF4752 28 vsvllKqwekrkkkskrqkAlnafydaFdldslepGstirva 69 +s++l + kr + q+ l++f ++d+ +l +G+ ++v FUN_001274-T1 270 TSLALAELYKRYSTGRLQRDLQEFLVTYDIRQLANGEEVVVS 311 57888899999999************************9986 PP == domain 3 score: -1.1 bits; conditional E-value: 1 DUF4752 47 AlnafydaFdldsle 61 ++fy +F+l++le FUN_001274-T1 414 SCDQFYRSFGLENLE 428 5689********998 PP >> DUF4313 Domain of unknown function (DUF4313) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 0.99 2.8e+03 16 67 .. 27 81 .. 17 104 .. 0.67 2 ? 10.1 0.2 0.00034 0.95 1 59 [. 296 355 .. 296 370 .. 0.84 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.99 DUF4313 16 llysqedglepfadvtvnLp.g.veakaqcafvdvn..dftrdvlkfiveneLGkv 67 l+++ + le ad +n + + + c+f+ v+ + +d+lk + e +L + FUN_001274-T1 27 LFIC-RGKLEHQADQDINNTlSlLRKLEDCNFLGVDylQLVKDILKAVEEWDLHEK 81 4444.455666666555544340455578999887622556888888888888665 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00034 DUF4313 1 tLevseYkedkalavllysqedgl.epfadvt.vnLpgveakaqcafvdvndftrdvlkfi 59 t ++ + ++++ + v +y +e ++ e d+t v+ g + + q ++++ ++ v++++ FUN_001274-T1 296 TYDIRQLANGEEVVVSVYIDEKEYwEALDDLTnVDQEGRGEEKQSKYLNEARMA-FVQNYL 355 67999**************************966777************55555.455554 PP >> DUF3067 Domain of unknown function (DUF3067) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2 5.7e+03 42 67 .. 1 26 [. 1 31 [. 0.89 2 ? 2.2 0.1 0.13 3.7e+02 46 74 .. 61 89 .. 51 101 .. 0.82 3 ? 7.2 0.1 0.0034 9.7 38 79 .. 83 124 .. 75 128 .. 0.88 4 ? 0.6 0.1 0.39 1.1e+03 40 74 .. 312 346 .. 296 360 .. 0.85 5 ? -0.8 0.1 1.1 3e+03 26 60 .. 537 571 .. 533 581 .. 0.79 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2 DUF3067 42 lseeeYlehLdavaellkalgaveqv 67 +se+eY + L ++ + l++++ +e++ FUN_001274-T1 1 MSETEYNSLLFRISKRLDNINDLEHI 26 699**************999998876 PP == domain 2 score: 2.2 bits; conditional E-value: 0.13 DUF3067 46 eYlehLdavaellkalgaveqvrefleet 74 +Yl+ ++++++ +++++ e+v +f ++ FUN_001274-T1 61 DYLQLVKDILKAVEEWDLHEKVVKFERTR 89 89*******************99875544 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0034 DUF3067 38 asfplseeeYlehLdavaellkalgaveqvrefleetkekPr 79 +f+ + +eY e + +v+++l++l+ +e +++ +++ ++ P+ FUN_001274-T1 83 VKFERTRREYKELVARVVSVLEELNDLERLMSIVARVRRIPE 124 47999***************************9999998885 PP == domain 4 score: 0.6 bits; conditional E-value: 0.39 DUF3067 40 fplseeeYlehLdavaellkalgaveqvrefleet 74 ++e+eY e Ld+++++ ++ + +e+ ++l+e+ FUN_001274-T1 312 VYIDEKEYWEALDDLTNVDQEGRGEEKQSKYLNEA 346 568999*******9999988888777777777766 PP == domain 5 score: -0.8 bits; conditional E-value: 1.1 DUF3067 26 iylqvmwkyleqasfplseeeYlehLdavaellka 60 i l v le+++ p++ +e e+L+++ +++ FUN_001274-T1 537 IPLGVFHLELEERNLPVQRNEIEEQLQELHVEVTE 571 5566777889999************9998766655 PP >> Kri1 KRI1-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.4 0.24 6.7e+02 20 42 .. 553 575 .. 547 587 .. 0.74 2 ? 11.2 1.9 0.0002 0.57 15 65 .. 599 648 .. 592 656 .. 0.67 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.24 Kri1 20 lKrkeieeklkkikeaaGeeeag 42 ++r+eiee+l+++ ++ e+e + FUN_001274-T1 553 VQRNEIEEQLQELHVEVTEKEDE 575 5799*********9999843333 PP == domain 2 score: 11.2 bits; conditional E-value: 0.0002 Kri1 15 krlKklKr..keieeklkkikeaaGeeeaglkelkeeeledlegdFDpeewdk 65 +rl++l++ eieeklkk++ + ++ k+l+ ++ + +++ +++e+ d+ FUN_001274-T1 599 QRLQELRKrkTEIEEKLKKVNANLQKQM---KKLEADTSRAVDELWNEERDDE 648 566655442279***********99555...5555555555566666665444 PP >> BORCS6 BLOC-1-related complex sub-unit 6 C-terminal helix # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.56 1.6e+03 53 75 .. 32 54 .. 4 73 .. 0.78 2 ? -1.9 0.0 1.8 5.2e+03 68 94 .. 94 120 .. 85 141 .. 0.56 3 ? 5.6 0.3 0.0089 25 6 37 .. 598 629 .. 593 639 .. 0.76 4 ? 4.1 0.1 0.025 72 50 98 .. 735 783 .. 726 785 .. 0.85 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.56 BORCS6 53 ektcdavdasiksmyeliakcee 75 k+ +++d+ i+++ +l+ k e+ FUN_001274-T1 32 GKLEHQADQDINNTLSLLRKLED 54 46778899999999999999886 PP == domain 2 score: -1.9 bits; conditional E-value: 1.8 BORCS6 68 eliakceeLnksmkpiyklaqqIkeik 94 el+a++ + +++++++ l + + ++ FUN_001274-T1 94 ELVARVVSVLEELNDLERLMSIVARVR 120 445555444444444444444444443 PP == domain 3 score: 5.6 bits; conditional E-value: 0.0089 BORCS6 6 pklLndlEkearkiaenldellrnlksslhem 37 + L++l k+ +i e+l+++ nl+++++++ FUN_001274-T1 598 IQRLQELRKRKTEIEEKLKKVNANLQKQMKKL 629 56788888888888888888888888888775 PP == domain 4 score: 4.1 bits; conditional E-value: 0.025 BORCS6 50 davektcdavdasiksmyeliakceeLnksmkpiyklaqqIkeikrlld 98 ++ve t +v ++ ++ li+ ++e+ ++++ ++ ++ Ik+i + l FUN_001274-T1 735 EGVEGTILEVLSKRWKTLDLISIMKEVRRTLSMQKNSSRTIKKITDNLS 783 5666667777777788999*************************99986 PP >> MutS_III MutS domain III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.1 0.9 2.6e+03 71 105 .. 13 49 .. 4 95 .. 0.48 2 ? 11.8 1.1 0.00011 0.32 66 155 .. 94 229 .. 70 572 .. 0.73 3 ? 2.9 0.7 0.058 1.6e+02 34 88 .. 587 640 .. 584 654 .. 0.82 4 ? -2.9 0.0 3.6 1e+04 68 102 .. 758 779 .. 730 794 .. 0.53 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.9 xxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxx RF MutS_III 71 lreslkklpDlerll....srialgkakprdllallesl 105 + ++l +++Dle +l +++ + +d+ + l+ l FUN_001274-T1 13 ISKRLDNINDLEHILficrGKLEH--QADQDINNTLSLL 49 445555555666655221112211..1112222222222 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00011 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx... RF MutS_III 66 elreelreslkklpDlerllsrialgkakprd....llallesleklpelkellaeekseelkelaeslaelleeaideeppellkeggvire... 154 el ++++ l++l+Dlerl+s +a + p++ + +++ ++ e k++l + e l+e l el ++ ++ e +e +k+ + ++ FUN_001274-T1 94 ELVARVVSVLEELNDLERLMSIVARVRRIPEErrndVHDVRSLVQV-LEEKNSLGIDCLEILRE---ILTELNDDELLSELSEFQKRRIEDETqer 185 55667778899999******96655544433322234442222222.22223322111111111...12233333333333333332222222333 PP ...........................................x RF MutS_III 155 ...........................................i 155 i FUN_001274-T1 186 rkareaavwssaraatqriigeirlrctfrtvsgvvllvgtglI 229 34555555666555555555555555555555555555555552 PP == domain 3 score: 2.9 bits; conditional E-value: 0.058 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxx RF MutS_III 34 sRlLrqwllqPltdleeIeeRldaVeellenselreelreslkklp.Dlerllsri 88 +R L + l+ + l+e+++R +ee l ++++ +l++++kkl+ D r++ + FUN_001274-T1 587 KRFLPKSLTTGIQRLQELRKRKTEIEEKL--KKVNANLQKQMKKLEaDTSRAVDEL 640 57777778888888999999999999977..7779999999999877999988765 PP == domain 4 score: -2.9 bits; conditional E-value: 3.6 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF MutS_III 68 reelreslkklpDlerllsrialgkakprdllall 102 +e+r +l+ ++ r +++i FUN_001274-T1 758 MKEVRRTLSMQKNSSRTIKKI-------------T 779 333333333333444444433.............3 PP >> Leptin Leptin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.0011 3.2 73 137 .. 36 97 .. 15 100 .. 0.87 2 ? 3.0 0.3 0.039 1.1e+02 72 135 .. 99 161 .. 96 169 .. 0.86 3 ? -2.1 0.2 1.5 4.1e+03 112 141 .. 573 603 .. 558 631 .. 0.60 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0011 Leptin 73 vqisnDlenLrallkllatsksCelekaseletleslekvleaslystevvaLeRlqksLlellk 137 q +D++n +ll+ + +C++ + l+ ++++ k++e+ +vv eR ++ +el+ FUN_001274-T1 36 HQADQDINNTLSLLR---KLEDCNFLGVDYLQLVKDILKAVEEWDLHEKVVKFERTRREYKELVA 97 567778888766666...5589************************************9999985 PP == domain 2 score: 3.0 bits; conditional E-value: 0.039 Leptin 72 vvqisnDlenLrallkllatsksCelekaseletleslekvleaslystevvaLeRlqksLlel 135 vv ++++l++L l+ ++a + + e+ ++++ + sl +vle+ s + Le l+++L el FUN_001274-T1 99 VVSVLEELNDLERLMSIVARVRRIPEERRNDVHDVRSLVQVLEEK-NSLGIDCLEILREILTEL 161 667889999999999***********************9999875.588888899999888877 PP == domain 3 score: -2.1 bits; conditional E-value: 1.5 Leptin 112 vleaslystevvaLeR.lqksLlellkqLdl 141 + e+ +y + +L+R l ksL + +++L++ FUN_001274-T1 573 EDEERRYKSDEPTLKRfLPKSLTTGIQRLQE 603 5555555555555555344555555555443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (796 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2586 (0.101233); expected 510.9 (0.02) Passed bias filter: 1206 (0.0472108); expected 510.9 (0.02) Passed Vit filter: 152 (0.00595028); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.47u 0.40s 00:00:00.87 Elapsed: 00:00:00.41 # Mc/sec: 7779.89 // Query: FUN_001274-T2 [L=796] Description: FUN_001274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-16 59.4 14.8 1.2e-10 41.9 0.8 3.4 3 DED Death effector domain 0.0039 17.5 0.6 0.11 12.9 1.1 2.7 2 Lectin_N Hepatic lectin, N-terminal domain ------ inclusion threshold ------ 0.028 15.0 0.3 0.12 13.0 0.2 2.1 2 DUF4313 Domain of unknown function (DUF4313) 0.13 12.8 0.0 5.6 7.6 0.0 3.3 3 DUF4752 Domain of unknown function (DUF4752) 0.16 12.7 0.0 0.63 10.8 0.0 2.1 1 DUF7648 Domain of unknown function (DUF7648) 0.2 12.7 3.7 5.2 8.1 0.0 4.2 4 DUF3067 Domain of unknown function (DUF3067) 0.42 11.3 4.9 25 5.6 0.3 3.8 4 BORCS6 BLOC-1-related complex sub-unit 6 C-terminal hel 0.96 10.5 7.8 0.57 11.2 1.9 2.7 2 Kri1 KRI1-like family 8.1 7.0 13.3 7 7.2 0.8 3.4 4 DUF1664 Protein of unknown function (DUF1664) Domain annotation for each model (and alignments): >> DED Death effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.9 0.8 4.4e-14 1.2e-10 1 81 [. 6 87 .. 6 88 .. 0.96 2 ! 25.3 2.2 6.6e-09 1.9e-05 26 81 .. 120 175 .. 97 176 .. 0.85 3 ? -2.6 0.2 3.3 9.3e+03 60 75 .. 611 625 .. 589 633 .. 0.54 Alignments for each domain: == domain 1 score: 41.9 bits; conditional E-value: 4.4e-14 DED 1 frklLleiseeLtsee.lesLkFLlkdkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +r+lL++is++L++ + le++ F +++k++++ ++i++ l+l++ Le+ g l+ d l ++++lLr +k L ++i+k++ FUN_001274-T2 6 YRSLLFRISKRLDEINaLEHILFICEEKLGHQTGQDIHNTLSLLRKLEESGSLGVDYLHVVKDLLRAVKEWGLREEIDKFES 87 8************96549*************************************************************985 PP == domain 2 score: 25.3 bits; conditional E-value: 6.6e-09 DED 26 dkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +ip+++ ++++++++l++ Le+++ l+ d l++L+e+L +++ ++Ll+++++++k FUN_001274-T2 120 RRIPEERRNDVHDVRSLVQVLEEKNFLGIDCLEILREILTELNDDELLSELTEFQK 175 479**************************************************987 PP == domain 3 score: -2.6 bits; conditional E-value: 3.3 DED 60 LeelLrrikrkdLlkk 75 +ee L++++ + L k+ FUN_001274-T2 611 IEEKLKKVNAN-LQKQ 625 34444444444.4444 PP >> Lectin_N Hepatic lectin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.23 6.5e+02 4 54 .. 172 228 .. 169 238 .. 0.80 2 ! 12.9 1.1 3.7e-05 0.11 64 122 .. 581 639 .. 551 650 .. 0.86 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.23 Lectin_N 4 dlQqldsEekdhqlrkg.....apppqsllqrlcsklrllllslgls.llLLvvvcv 54 ++Q+ E+++++ rk ++++++ +qr++ + rl ++s ++LLv + FUN_001274-T2 172 EFQKRRIEDETQERRKAreaavWSSARAATQRIIGEIRLRCTFRTVSgVVLLVGTGL 228 7899999999988888888888899999*******9999887766654778887655 PP == domain 2 score: 12.9 bits; conditional E-value: 3.7e-05 Lectin_N 64 eeletLketfsNfssstlaevqalssqggslgdkvtsleaklekkqqdlkadhselllh 122 ++ tLk + ++ + +q+l+ + ++++k++ ++a+l+k+ ++l+ad s + + FUN_001274-T2 581 SDEPTLKRFLPKSLTTGIQRLQELRKRKTEIEEKLKKVNANLQKQMKKLEADTSRAVDE 639 555677777766667777899********************************987655 PP >> DUF4313 Domain of unknown function (DUF4313) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 2 5.8e+03 56 70 .. 26 40 .. 18 43 .. 0.81 2 ? 13.0 0.2 4.3e-05 0.12 1 59 [. 296 355 .. 296 370 .. 0.86 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 2 DUF4313 56 lkfiveneLGkvtgr 70 fi e +LG+ tg+ FUN_001274-T2 26 ILFICEEKLGHQTGQ 40 459********9996 PP == domain 2 score: 13.0 bits; conditional E-value: 4.3e-05 DUF4313 1 tLevseYkedkalavllysqedgl.epfadvt.vnLpgveakaqcafvdvndftrdvlkfi 59 t ++ + ++++ + v +y +e ++ e d+t vn g + + q ++++ ++ v++++ FUN_001274-T2 296 TYDIRQLANGEEVVVSVYIDEKEYwEALDDLTnVNQEGRGEEKQSKYLNEARMA-FVQNYL 355 67999**************************989999************55555.455555 PP >> DUF4752 Domain of unknown function (DUF4752) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.33 9.5e+02 44 78 .. 232 266 .. 230 271 .. 0.86 2 ? 7.6 0.0 0.002 5.6 28 69 .. 270 311 .. 267 315 .. 0.92 3 ? -1.1 0.0 1 2.9e+03 47 61 .. 414 428 .. 405 430 .. 0.83 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.33 DUF4752 44 rqkAlnafydaFdldslepGstirvatkgdlvili 78 r ++f +aF + l +++r +++g + ++ FUN_001274-T2 232 RCFTFDDFVQAFTVAILPASNVLRTISEGSVCFMV 266 5667899**********************998877 PP == domain 2 score: 7.6 bits; conditional E-value: 0.002 DUF4752 28 vsvllKqwekrkkkskrqkAlnafydaFdldslepGstirva 69 +s++l + kr + q+ l++f ++d+ +l +G+ ++v FUN_001274-T2 270 TSLALEELYKRYSTGRLQRDLQEFLVTYDIRQLANGEEVVVS 311 5788999999****************************9986 PP == domain 3 score: -1.1 bits; conditional E-value: 1 DUF4752 47 AlnafydaFdldsle 61 ++fy +F+l++le FUN_001274-T2 414 SCDQFYRSFGLENLE 428 5689********998 PP >> DUF7648 Domain of unknown function (DUF7648) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00022 0.63 24 60 .. 41 77 .. 36 79 .. 0.92 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00022 DUF7648 24 avlqhwkdlrKpngeryayssylhAvldcLRnrseWA 60 +++ ++ lrK ++ + ylh v+d LR +eW FUN_001274-T2 41 DIHNTLSLLRKLEESGSLGVDYLHVVKDLLRAVKEWG 77 58999999****************************5 PP >> DUF3067 Domain of unknown function (DUF3067) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1 2.8e+03 42 68 .. 1 27 [. 1 54 [. 0.79 2 ? 8.1 0.0 0.0018 5.2 36 79 .. 81 124 .. 61 129 .. 0.90 3 ? 1.4 0.1 0.23 6.6e+02 39 75 .. 311 347 .. 297 358 .. 0.88 4 ? -0.8 0.1 1.1 3e+03 26 60 .. 537 571 .. 533 581 .. 0.79 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1 DUF3067 42 lseeeYlehLdavaellkalgaveqvr 68 +s++eY++ L ++ + l++++a+e++ FUN_001274-T2 1 MSKAEYRSLLFRISKRLDEINALEHIL 27 6899*****************999985 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0018 DUF3067 36 eqasfplseeeYlehLdavaellkalgaveqvrefleetkekPr 79 e +f+ + +eY e + +v ++l++l+ +e +++ +++ ++ P+ FUN_001274-T2 81 EIDKFESTRREYKELVARVINVLEELNDLERLMSIVARVRRIPE 124 45789*****************************9999998885 PP == domain 3 score: 1.4 bits; conditional E-value: 0.23 DUF3067 39 sfplseeeYlehLdavaellkalgaveqvrefleetk 75 s ++e+eY e Ld+++++ ++ + +e+ ++l+e++ FUN_001274-T2 311 SVYIDEKEYWEALDDLTNVNQEGRGEEKQSKYLNEAR 347 55689************99999888888888887765 PP == domain 4 score: -0.8 bits; conditional E-value: 1.1 DUF3067 26 iylqvmwkyleqasfplseeeYlehLdavaellka 60 i l v le+++ p++ +e e+L+++ +++ FUN_001274-T2 537 IPLGVFHLELEERNLPVQRNEIEEQLQELHVEVTE 571 5566777889999************9998766655 PP >> BORCS6 BLOC-1-related complex sub-unit 6 C-terminal helix # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 1 3e+03 53 75 .. 32 54 .. 4 86 .. 0.76 2 ? 0.1 0.0 0.46 1.3e+03 57 95 .. 83 121 .. 40 124 .. 0.75 3 ? 5.6 0.3 0.0089 25 6 37 .. 598 629 .. 593 639 .. 0.76 4 ? 4.1 0.1 0.025 72 50 98 .. 735 783 .. 726 785 .. 0.85 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1 BORCS6 53 ektcdavdasiksmyeliakcee 75 ek+++++ + i ++ +l+ k ee FUN_001274-T2 32 EKLGHQTGQDIHNTLSLLRKLEE 54 56777777777888888887776 PP == domain 2 score: 0.1 bits; conditional E-value: 0.46 BORCS6 57 davdasiksmyeliakceeLnksmkpiyklaqqIkeikr 95 d+ ++ ++ +el+a++ + +++++++ l + + ++r FUN_001274-T2 83 DKFESTRREYKELVARVINVLEELNDLERLMSIVARVRR 121 455566677778888888888888888888777776665 PP == domain 3 score: 5.6 bits; conditional E-value: 0.0089 BORCS6 6 pklLndlEkearkiaenldellrnlksslhem 37 + L++l k+ +i e+l+++ nl+++++++ FUN_001274-T2 598 IQRLQELRKRKTEIEEKLKKVNANLQKQMKKL 629 56788888888888888888888888888775 PP == domain 4 score: 4.1 bits; conditional E-value: 0.025 BORCS6 50 davektcdavdasiksmyeliakceeLnksmkpiyklaqqIkeikrlld 98 ++ve t +v ++ ++ li+ ++e+ ++++ ++ ++ Ik+i + l FUN_001274-T2 735 EGVEGTILEVLSKRWKTLDLISIMKEVRRTLSMQKNSSRTIKKITDNLS 783 5666667777777788999*************************99986 PP >> Kri1 KRI1-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.4 0.24 6.7e+02 20 42 .. 553 575 .. 547 587 .. 0.74 2 ? 11.2 1.9 0.0002 0.57 15 65 .. 599 648 .. 592 656 .. 0.67 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.24 Kri1 20 lKrkeieeklkkikeaaGeeeag 42 ++r+eiee+l+++ ++ e+e + FUN_001274-T2 553 VQRNEIEEQLQELHVEVTEKEDE 575 5799*********9999843333 PP == domain 2 score: 11.2 bits; conditional E-value: 0.0002 Kri1 15 krlKklKr..keieeklkkikeaaGeeeaglkelkeeeledlegdFDpeewdk 65 +rl++l++ eieeklkk++ + ++ k+l+ ++ + +++ +++e+ d+ FUN_001274-T2 599 QRLQELRKrkTEIEEKLKKVNANLQKQM---KKLEADTSRAVDELWNEERDDE 648 566655442279***********99555...5555555555566666665444 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.4 0.0025 7 53 116 .. 81 143 .. 66 145 .. 0.88 2 ? -2.9 0.1 3.3 9.3e+03 38 59 .. 550 571 .. 548 577 .. 0.58 3 ? 7.2 0.8 0.0025 7 46 92 .. 594 640 .. 586 646 .. 0.77 4 ? -1.4 0.1 1.1 3.2e+03 23 57 .. 749 782 .. 746 793 .. 0.54 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0025 DUF1664 53 vseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesk 116 ++ ++t++e ++ ++rv + l+e +++ + + + v+ vr+ ++ ++dv+ v+++v+ le+k FUN_001274-T2 81 EIDKFESTRREYKELVARVINVLEELNDLERLM-SIVARVRRIPEERRNDVHDVRSLVQVLEEK 143 557789999*****************9998776.679************************987 PP == domain 2 score: -2.9 bits; conditional E-value: 3.3 DUF1664 38 nlsdavesvskqleqvseslaa 59 nl ++++ +ql+++ ++++ FUN_001274-T2 550 NLPVQRNEIEEQLQELHVEVTE 571 5555566666666666655554 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0025 DUF1664 46 vskqleqvseslaatKkeLsqridrvdkkldeqk.eiskeikeevtev 92 +++ ++++ ++l++ K e+++++++v+++l++q+ ++ ++++++v e+ FUN_001274-T2 594 LTTGIQRL-QELRKRKTEIEEKLKKVNANLQKQMkKLEADTSRAVDEL 640 55566555.5799***************99876516777788777665 PP == domain 4 score: -1.4 bits; conditional E-value: 1.1 DUF1664 23 wkGlslsDlmfvTkrnlsdavesvskqleqvsesl 57 wk l l ++m +r ls +s s+ ++++ ++l FUN_001274-T2 749 WKTLDLISIMKEVRRTLSMQKNS-SRTIKKITDNL 782 66666666666666655543322.33344444333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (796 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2529 (0.0990018); expected 510.9 (0.02) Passed bias filter: 1226 (0.0479937); expected 510.9 (0.02) Passed Vit filter: 156 (0.00610687); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.50u 0.41s 00:00:00.90 Elapsed: 00:00:00.43 # Mc/sec: 7415.04 // Query: FUN_001275-T1 [L=757] Description: FUN_001275 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-14 54.1 16.5 2.9e-07 31.1 2.6 3.8 3 DED Death effector domain ------ inclusion threshold ------ 0.011 16.0 0.4 0.04 14.2 0.0 2.2 2 TRADD-like_N TRADD-like N-terminal domain 0.14 12.7 0.0 1.4e+02 3.1 0.0 3.4 3 DUF4752 Domain of unknown function (DUF4752) 0.22 11.9 0.6 9.2 6.7 0.0 2.9 2 Rop-like Rop-like 0.27 11.8 4.9 1.4 9.4 1.6 3.1 3 Mei5_like Putative double-strand recombination repair-lik 3.9 8.2 10.7 1e+02 3.6 8.0 3.7 2 MutS_III MutS domain III 4.9 7.8 8.4 0.4 11.3 0.9 3.1 3 DksA-like_N DnaK suppressor protein-like, N-terminal domain Domain annotation for each model (and alignments): >> DED Death effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.1 2.6 8e-11 2.9e-07 1 80 [. 6 83 .. 6 85 .. 0.93 2 ! 28.7 2.5 4.6e-10 1.7e-06 26 81 .. 117 172 .. 100 173 .. 0.89 3 ? 0.7 0.1 0.25 9.2e+02 41 77 .. 435 472 .. 400 475 .. 0.79 Alignments for each domain: == domain 1 score: 31.1 bits; conditional E-value: 8e-11 DED 1 frklLleiseeLtsee.lesLkFLlkdkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekyk 80 +++lLl+ise+L++ + l+ + F +++k+ e+i+++l++++ Le++g l+ d l+ ++++L+ + L ++i k++ FUN_001275-T1 6 YNSLLLRISERLDDINaLNRILFICREKL---AGEDIHDSLSMLIKLEQKGFLGVDELQEVKDILKAVEEWGLREEIIKFE 83 789**********96549**********9...55899**************************************999987 PP == domain 2 score: 28.7 bits; conditional E-value: 4.6e-10 DED 26 dkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +ip+++ ++i+++++lf+ Le+++ l+ d+l +L+e+L ++k ++Ll+++ +++k FUN_001275-T1 117 RRIPEERKNDIHDLRSLFQVLEDMNFLGIDRLGILREILTELKNHELLTELAEFQK 172 46999***********************************************9987 PP == domain 3 score: 0.7 bits; conditional E-value: 0.25 DED 41 dlfeeLekqgllsednl.dlLeelLrrikrkdLlkkie 77 +f+e ++ g+l +d + +l+ +++r ++ +dL++ +e FUN_001275-T1 435 RVFREIRNIGKLFPDTPvKLVIDVCRALHLHDLVELLE 472 57888888888888876699999**********98776 PP >> TRADD-like_N TRADD-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 2.5 9.1e+03 36 59 .. 145 169 .. 144 171 .. 0.78 2 ? 14.2 0.0 1.1e-05 0.04 25 65 .. 254 294 .. 247 296 .. 0.91 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 2.5 TRADD-like_N 36 gsreeil.erllalynsGeLrellg 59 ++r++il e l +l n L+el+ FUN_001275-T1 145 IDRLGILrEILTELKNHELLTELAE 169 6888888888888888888888865 PP == domain 2 score: 14.2 bits; conditional E-value: 1.1e-05 TRADD-like_N 25 ieeGSilvtfkgsreeilerllalynsGeLrellglsvete 65 i+eGS+++t++ + +le l ++y G+L++ l+ +++t+ FUN_001275-T1 254 ISEGSVCFTVRAETSVALEELYERYSTGRLQKDLQEFLVTD 294 89*****************************9888888887 PP >> DUF4752 Domain of unknown function (DUF4752) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.042 1.5e+02 43 77 .. 228 262 .. 226 267 .. 0.88 2 ? 3.1 0.0 0.038 1.4e+02 28 67 .. 267 306 .. 261 312 .. 0.87 3 ? 2.2 0.0 0.073 2.7e+02 48 66 .. 419 437 .. 414 444 .. 0.82 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.042 DUF4752 43 krqkAlnafydaFdldslepGstirvatkgdlvil 77 +r l++f +aF + l +++r +++g + FUN_001275-T1 228 RRCSTLEDFVEAFRVATLPAANALRAISEGSVCFT 262 678899*********************99998765 PP == domain 2 score: 3.1 bits; conditional E-value: 0.038 DUF4752 28 vsvllKqwekrkkkskrqkAlnafydaFdldslepGstir 67 +sv+l + r + qk l++f + d+ +l +G+ ++ FUN_001275-T1 267 TSVALEELYERYSTGRLQKDLQEFLVTDDIRQLADGEEVV 306 68888899999999999*******************9886 PP == domain 3 score: 2.2 bits; conditional E-value: 0.073 DUF4752 48 lnafydaFdldslepGsti 66 n+fy++F+ld+l+ + FUN_001275-T1 419 CNQFYQSFGLDKLHTARVF 437 699*********9876665 PP >> Rop-like Rop-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.0 0.0025 9.2 2 27 .. 105 130 .. 104 132 .. 0.94 2 ? 1.9 0.4 0.081 3e+02 21 30 .. 461 470 .. 458 473 .. 0.83 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0025 Rop-like 2 dieeLkkevkKlnskAtqakmdLHDL 27 d+e L v + +++ + k d+HDL FUN_001275-T1 105 DLERLMSTVYRVRRIPEERKNDIHDL 130 899999*******************9 PP == domain 2 score: 1.9 bits; conditional E-value: 0.081 Rop-like 21 kmdLHDLaEd 30 + LHDL+E FUN_001275-T1 461 ALHLHDLVEL 470 678*****95 PP >> Mei5_like Putative double-strand recombination repair-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.15 5.6e+02 70 96 .. 81 107 .. 64 117 .. 0.80 2 ? -1.1 0.0 0.74 2.7e+03 94 111 .. 416 433 .. 396 435 .. 0.71 3 ? 9.4 1.6 0.0004 1.4 32 75 .. 565 605 .. 545 611 .. 0.76 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.15 Mei5_like 70 dleeliekwkevieeciiiLkkefelk 96 e++ +ke+ie+ i +L++ +l+ FUN_001275-T1 81 KFESMRGEYKELIERVIGVLEDLNDLE 107 56788889************9877665 PP == domain 2 score: -1.1 bits; conditional E-value: 0.74 Mei5_like 94 elkakevfkafeLkkygf 111 e+ ++ +++f L+k++ FUN_001275-T1 416 EVSCNQFYQSFGLDKLHT 433 6777899*******9985 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0004 Mei5_like 32 sekkknrRySDqFkdplfiekdiyrKLkliekfkeknkdleeli 75 ek+++ ++ D F ++ + + r+L++ie+ +ek+k++e i FUN_001275-T1 565 CEKERSLKFDDDFEER---KAELERRLQMIEQSEEKKKNMEAHI 605 3444445566666655...56889****************9877 PP >> MutS_III MutS domain III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.11 4.1e+02 50 136 .. 12 95 .. 10 98 .. 0.60 2 ? 3.6 8.0 0.027 1e+02 65 155 .. 90 252 .. 59 749 .. 0.80 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.11 xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxx.xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF MutS_III 50 eIeeRldaVeellenselreelreslkk..lpDlerllsrialgka.kprd...llallesleklpelkellaeekseelkelaeslaellee 136 +I eRld + + l + + re+l + ++D +l ++ ++ ++ ++ +l+++e++ +e++ + +s + +++el+e+ FUN_001275-T1 12 RISERLDDINA-L--NRILFICREKLAGedIHDSLSMLIKLEQKGFlGVDElqeVKDILKAVEEWGLREEII-KFESM--RG---EYKELIER 95 6999******9.8..566788888877657888888888887765534444222444666666644333333.23222..11...44566666 PP == domain 2 score: 3.6 bits; conditional E-value: 0.027 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxx..xxxxxxxxxxxxxxxxxxxx RF MutS_III 65 selreelreslkklpDlerllsrialgkakprd....llallesleklpelkellaeekseelkelae...sla..elleeaideeppellkeggv 151 +el e++ l++l+Dlerl+s ++ + p++ + l++ ++ l++ ++l + l+e +l+ ell+e + e + + ++ FUN_001275-T1 90 KELIERVIGVLEDLNDLERLMSTVYRVRRIPEErkndIHDLRSLFQVLEDMNFLGIDRLGI----LREiltELKnhELLTE-LAEFQKRRVEYETY 180 344556666677778*******887765555543333444444444444444443322222....1111112222244444.44433333333333 PP xxx....................................................................x RF MutS_III 152 ire....................................................................i 155 + + FUN_001275-T1 181 EKRkaqgaavwssartatqrligevrvhctfrtlsgvvlvvgtglilrrcstledfveafrvatlpaanalR 252 333677777777777777777777777777777777777777777555433333333333333333333330 PP >> DksA-like_N DnaK suppressor protein-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.1 0.91 3.3e+03 36 51 .. 156 171 .. 152 176 .. 0.80 2 ? -2.2 0.1 1.7 6.3e+03 37 53 .. 313 329 .. 310 334 .. 0.85 3 ? 11.3 0.9 0.00011 0.4 3 30 .. 575 602 .. 573 605 .. 0.85 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.91 DksA-like_N 36 vErendEVLeelGeag 51 +E +n E L el+e + FUN_001275-T1 156 TELKNHELLTELAEFQ 171 6899999999999865 PP == domain 2 score: -2.2 bits; conditional E-value: 1.7 DksA-like_N 37 ErendEVLeelGeagee 53 E+e E L++l ++g+e FUN_001275-T1 313 EKEFREALDGLMNVGQE 329 6777899****999997 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00011 DksA-like_N 3 kiLraRraelearLhkieddLdeprnkd 30 + +++R+aele+rL+ ie+ ++++n + FUN_001275-T1 575 DDFEERKAELERRLQMIEQSEEKKKNME 602 56799**************988888865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (757 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1329 (0.0520258); expected 510.9 (0.02) Passed bias filter: 794 (0.0310824); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.47u 0.39s 00:00:00.86 Elapsed: 00:00:00.43 # Mc/sec: 7025.03 // Query: FUN_001276-T1 [L=184] Description: FUN_001276 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00042 20.8 8.9 0.0011 19.5 8.9 1.8 1 PHD PHD-finger ------ inclusion threshold ------ 0.086 13.5 2.5 0.086 13.5 2.5 1.8 2 Prok-RING_1 Prokaryotic RING finger family 1 0.17 12.5 0.6 0.17 12.5 0.6 1.7 2 PHD_5 PhD finger domain Domain annotation for each model (and alignments): >> PHD PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 8.9 1.3e-07 0.0011 1 47 [] 5 58 .. 5 58 .. 0.83 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 1.3e-07 PHD 1 CkvCkk.sdedeelvlCdgCkkwfHlkClk.pplekeelpeg.....ewlCpeC 47 C C++ ++++e ++CdgC kw H +C + ++++ +++ + +w+C C FUN_001276-T1 5 CISCNRtVTARQEAIQCDGCLKWNHRTCNTgITQQAYREAVRagadiSWCCLPC 58 889***9899******************7526666555555578999****999 PP >> Prok-RING_1 Prokaryotic RING finger family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 2.5 1e-05 0.086 5 35 .. 3 33 .. 1 37 [. 0.94 2 ? -2.1 0.1 0.73 6.2e+03 12 23 .. 43 54 .. 40 60 .. 0.68 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1e-05 Prok-RING_1 5 kkCtvCseelkdgdDiVvCdeCgtsyHreCy 35 kC +C ++ ++ ++Cd C Hr C FUN_001276-T1 3 DKCISCNRTVTARQEAIQCDGCLKWNHRTCN 33 59****************************5 PP == domain 2 score: -2.1 bits; conditional E-value: 0.73 Prok-RING_1 12 eelkdgdDiVvC 23 e ++ g Di C FUN_001276-T1 43 EAVRAGADISWC 54 667778888776 PP >> PHD_5 PhD finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.6 2e-05 0.17 23 38 .. 18 33 .. 4 45 .. 0.85 2 ? -3.9 0.5 2.7 2.3e+04 30 38 .. 172 180 .. 170 183 .. 0.71 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2e-05 PHD_5 23 miqceeclcwqhsvcm 38 iqc+ cl w+h c FUN_001276-T1 18 AIQCDGCLKWNHRTCN 33 59***********995 PP == domain 2 score: -3.9 bits; conditional E-value: 2.7 PHD_5 30 lcwqhsvcm 38 lc h c FUN_001276-T1 172 LCVAHGWCS 180 788888775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 742 (0.0290468); expected 510.9 (0.02) Passed bias filter: 373 (0.0146017); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1864.93 // Query: FUN_001277-T1 [L=249] Description: FUN_001277 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 13.1 3.0 0.25 12.4 1.1 2.2 2 zf-C2H2 Zinc finger, C2H2 type 0.18 13.1 4.5 0.53 11.6 2.6 2.4 2 zf-C2H2_4 C2H2-type zinc finger 0.19 10.4 16.3 0.25 10.1 16.3 1.1 1 CDC45 CDC45 0.96 10.1 4.0 6.1 7.5 0.1 2.6 2 Csm6_6H Csm6 6H domain 5.8 7.9 7.4 4.9 8.2 0.1 2.9 3 DUF7615 Domain of unknown function (DUF7615) Domain annotation for each model (and alignments): >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 1.1 4.9e-05 0.25 3 23 .] 5 25 .. 3 25 .. 0.91 2 ? 0.3 0.1 0.33 1.7e+03 5 13 .. 25 33 .. 24 37 .. 0.81 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.9e-05 zf-C2H2 3 CpdCgksFsrksnLkrHlrtH 23 C+ Cg++Fsrk n rH H FUN_001277-T1 5 CQFCGRAFSRKFNRDRHEAAH 25 89**************98766 PP == domain 2 score: 0.3 bits; conditional E-value: 0.33 zf-C2H2 5 dCgksFsrk 13 +C k+F + FUN_001277-T1 25 HCSKRFDDE 33 7*****875 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 2.6 0.0001 0.53 1 23 [. 3 25 .. 3 25 .. 0.93 2 ? 2.0 0.0 0.13 6.7e+02 5 16 .. 25 36 .. 24 38 .. 0.82 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.0001 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 ++C +Cg+ Fs+k + rH + h FUN_001277-T1 3 HCCQFCGRAFSRKFNRDRHEAAH 25 69*************999*9988 PP == domain 2 score: 2.0 bits; conditional E-value: 0.13 zf-C2H2_4 5 iCgksFsskkaL 16 +C+k+F + +++ FUN_001277-T1 25 HCSKRFDDEEGM 36 8*****987765 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 16.3 4.8e-05 0.25 106 220 .. 30 155 .. 16 178 .. 0.43 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 4.8e-05 CDC45 106 ldDgdieeelqeekeayealeeeeeedeede......eeeeeddeeeeeeeeeeedeeeeeedeeeskkkrk..sesdeeee........eeddee 185 +dD++ ++l++++e++e+ +e+ ed+++e +e +d +++eee e e++++ e+ +++ ++++ +++ +ee +ee FUN_001277-T1 30 FDDEEGMTSLSNDEESIEQRTENFYEDDDEEnnstedGDEADDHDDDEEEGEGGEETDNGETGSDT--ENDEvdPWDKLREEaisdlnsaW--EEE 121 677776677777666555555554444222222221112222222222222222222222222222..22223344444444455553221..222 PP CDC45 186 ersrkrrrseesakklrkqlkkerreyeavlekyY 220 +++ r+ + +++++ ++++++ y+++l++ Y FUN_001277-T1 122 VQENLRQGLQ-KDDAEIQASHRLLPVYRKKLRHLY 155 2222222222.222222334444444444444444 PP >> Csm6_6H Csm6 6H domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.7 0.03 1.5e+02 51 92 .. 103 143 .. 101 144 .. 0.85 2 ? 7.5 0.1 0.0012 6.1 36 63 .. 169 196 .. 152 221 .. 0.78 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.03 Csm6_6H 51 WDkldhkeAldrlskvlseellidenkglnallealkaqlai 92 WDkl+ +eA+ l++ ee++ + +gl++ ++a + FUN_001277-T1 103 WDKLR-EEAISDLNSAWEEEVQENLRQGLQKDDAEIQASHRL 143 ****9.99*******999999999999999888777776665 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0012 Csm6_6H 36 keykaykllaegyleWDkldhkeAldrl 63 ++ k++ + + ++e D++d+ eA+++ FUN_001277-T1 169 PVHKKVMKTLRSFMEDDEMDYTEAVEAA 196 56677788889**************974 PP >> DUF7615 Domain of unknown function (DUF7615) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.045 2.3e+02 46 85 .. 14 53 .. 10 56 .. 0.89 2 ? -0.3 0.5 0.42 2.1e+03 8 47 .. 118 157 .. 112 167 .. 0.82 3 ? 8.2 0.1 0.00095 4.9 9 50 .. 171 212 .. 163 244 .. 0.83 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.045 DUF7615 46 qqLdkekselakrtssadesalleavlkrveqikrEvkkl 85 ++++++++e a++++ d+++ ++++ + +e i++ ++++ FUN_001277-T1 14 RKFNRDRHEAAHCSKRFDDEEGMTSLSNDEESIEQRTENF 53 78899****************************9988877 PP == domain 2 score: -0.3 bits; conditional E-value: 0.42 DUF7615 8 ledeidqvLqeLkksqelEYklAeekLyaqkkyllnlyqq 47 e+e+++ L++ + ++E + + L +k l +ly q FUN_001277-T1 118 WEEEVQENLRQGLQKDDAEIQASHRLLPVYRKKLRHLYLQ 157 6889999988877778899999999999999999999977 PP == domain 3 score: 8.2 bits; conditional E-value: 0.00095 DUF7615 9 edeidqvLqeLkksqelEYklAeekLyaqkkyllnlyqqLdk 50 +++ ++L+++ + e++Y A e +++kylln L++ FUN_001277-T1 171 HKKVMKTLRSFMEDDEMDYTEAVEAAISKRKYLLNSLFDLEH 212 5789999**************************998888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (249 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1925 (0.0753572); expected 510.9 (0.02) Passed bias filter: 813 (0.0318262); expected 510.9 (0.02) Passed Vit filter: 107 (0.00418869); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 2413.50 // Query: FUN_001278-T1 [L=249] Description: FUN_001278 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 13.1 3.0 0.25 12.4 1.1 2.2 2 zf-C2H2 Zinc finger, C2H2 type 0.18 13.1 4.5 0.53 11.6 2.6 2.4 2 zf-C2H2_4 C2H2-type zinc finger 0.19 10.4 16.3 0.25 10.1 16.3 1.1 1 CDC45 CDC45 0.96 10.1 4.0 6.1 7.5 0.1 2.6 2 Csm6_6H Csm6 6H domain 5.8 7.9 7.4 4.9 8.2 0.1 2.9 3 DUF7615 Domain of unknown function (DUF7615) Domain annotation for each model (and alignments): >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 1.1 4.9e-05 0.25 3 23 .] 5 25 .. 3 25 .. 0.91 2 ? 0.3 0.1 0.33 1.7e+03 5 13 .. 25 33 .. 24 37 .. 0.81 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.9e-05 zf-C2H2 3 CpdCgksFsrksnLkrHlrtH 23 C+ Cg++Fsrk n rH H FUN_001278-T1 5 CQFCGRAFSRKFNRDRHEAAH 25 89**************98766 PP == domain 2 score: 0.3 bits; conditional E-value: 0.33 zf-C2H2 5 dCgksFsrk 13 +C k+F + FUN_001278-T1 25 HCSKRFDDE 33 7*****875 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 2.6 0.0001 0.53 1 23 [. 3 25 .. 3 25 .. 0.93 2 ? 2.0 0.0 0.13 6.7e+02 5 16 .. 25 36 .. 24 38 .. 0.82 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.0001 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 ++C +Cg+ Fs+k + rH + h FUN_001278-T1 3 HCCQFCGRAFSRKFNRDRHEAAH 25 69*************999*9988 PP == domain 2 score: 2.0 bits; conditional E-value: 0.13 zf-C2H2_4 5 iCgksFsskkaL 16 +C+k+F + +++ FUN_001278-T1 25 HCSKRFDDEEGM 36 8*****987765 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 16.3 4.8e-05 0.25 106 220 .. 30 155 .. 16 178 .. 0.43 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 4.8e-05 CDC45 106 ldDgdieeelqeekeayealeeeeeedeede......eeeeeddeeeeeeeeeeedeeeeeedeeeskkkrk..sesdeeee........eeddee 185 +dD++ ++l++++e++e+ +e+ ed+++e +e +d +++eee e e++++ e+ +++ ++++ +++ +ee +ee FUN_001278-T1 30 FDDEEGMTSLSNDEESIEQRTENFYEDDDEEnnstedGDEADDHDDDEEEGEGGEETDNGETGSDT--ENDEvdPWDKLREEaisdlnsaW--EEE 121 677776677777666555555554444222222221112222222222222222222222222222..22223344444444455553221..222 PP CDC45 186 ersrkrrrseesakklrkqlkkerreyeavlekyY 220 +++ r+ + +++++ ++++++ y+++l++ Y FUN_001278-T1 122 VQENLRQGLQ-KDDAEIQASHRLLPVYRKKLRHLY 155 2222222222.222222334444444444444444 PP >> Csm6_6H Csm6 6H domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.7 0.03 1.5e+02 51 92 .. 103 143 .. 101 144 .. 0.85 2 ? 7.5 0.1 0.0012 6.1 36 63 .. 169 196 .. 152 221 .. 0.78 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.03 Csm6_6H 51 WDkldhkeAldrlskvlseellidenkglnallealkaqlai 92 WDkl+ +eA+ l++ ee++ + +gl++ ++a + FUN_001278-T1 103 WDKLR-EEAISDLNSAWEEEVQENLRQGLQKDDAEIQASHRL 143 ****9.99*******999999999999999888777776665 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0012 Csm6_6H 36 keykaykllaegyleWDkldhkeAldrl 63 ++ k++ + + ++e D++d+ eA+++ FUN_001278-T1 169 PVHKKVMKTLRSFMEDDEMDYTEAVEAA 196 56677788889**************974 PP >> DUF7615 Domain of unknown function (DUF7615) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.045 2.3e+02 46 85 .. 14 53 .. 10 56 .. 0.89 2 ? -0.3 0.5 0.42 2.1e+03 8 47 .. 118 157 .. 112 167 .. 0.82 3 ? 8.2 0.1 0.00095 4.9 9 50 .. 171 212 .. 163 244 .. 0.83 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.045 DUF7615 46 qqLdkekselakrtssadesalleavlkrveqikrEvkkl 85 ++++++++e a++++ d+++ ++++ + +e i++ ++++ FUN_001278-T1 14 RKFNRDRHEAAHCSKRFDDEEGMTSLSNDEESIEQRTENF 53 78899****************************9988877 PP == domain 2 score: -0.3 bits; conditional E-value: 0.42 DUF7615 8 ledeidqvLqeLkksqelEYklAeekLyaqkkyllnlyqq 47 e+e+++ L++ + ++E + + L +k l +ly q FUN_001278-T1 118 WEEEVQENLRQGLQKDDAEIQASHRLLPVYRKKLRHLYLQ 157 6889999988877778899999999999999999999977 PP == domain 3 score: 8.2 bits; conditional E-value: 0.00095 DUF7615 9 edeidqvLqeLkksqelEYklAeekLyaqkkyllnlyqqLdk 50 +++ ++L+++ + e++Y A e +++kylln L++ FUN_001278-T1 171 HKKVMKTLRSFMEDDEMDYTEAVEAAISKRKYLLNSLFDLEH 212 5789999**************************998888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (249 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1925 (0.0753572); expected 510.9 (0.02) Passed bias filter: 813 (0.0318262); expected 510.9 (0.02) Passed Vit filter: 107 (0.00418869); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 2382.25 // Query: FUN_001279-T1 [L=104] Description: FUN_001279 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 655 (0.025641); expected 510.9 (0.02) Passed bias filter: 427 (0.0167156); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1037.64 // Query: FUN_001280-T1 [L=103] Description: FUN_001280 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 M2AP_beta_dom MIC2-associated protein, central beta-domain Domain annotation for each model (and alignments): >> M2AP_beta_dom MIC2-associated protein, central beta-domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 6.8e-06 0.17 62 86 .. 65 89 .. 56 100 .. 0.82 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 6.8e-06 M2AP_beta_dom 62 kdiddvpedkagkcflkkfaeedss 86 kd + + gkcfl++f+e+ds FUN_001280-T1 65 KDYNMKYSSMGGKCFLQRFSEDDSQ 89 56666677889************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 611 (0.0239186); expected 510.9 (0.02) Passed bias filter: 540 (0.0211392); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1056.49 // Query: FUN_001281-T1 [L=185] Description: FUN_001281 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-40 137.6 0.4 8.3e-40 137.3 0.4 1.1 1 GRDP-like Glycine-rich domain-containing protein-like ------ inclusion threshold ------ 0.074 13.4 0.2 0.28 11.6 0.1 2.0 3 DUF6908 Domain of unknown function (DUF6908) Domain annotation for each model (and alignments): >> GRDP-like Glycine-rich domain-containing protein-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 137.3 0.4 6.5e-44 8.3e-40 1 143 [] 6 141 .. 6 141 .. 0.95 Alignments for each domain: == domain 1 score: 137.3 bits; conditional E-value: 6.5e-44 GRDP-like 1 sYkedceelfgkiidkkaidesneekalsrteelwkrlypeepfeleekklkakeeeveessssikedLvsavkrqsefyyqvssphvseevflee 96 sY++dc+e++++++d+k ++ +++e l++++ lw++ yp epfe+e l+ v + +s+i++d+++a +rq+ fyyqvs ph+ +e+fl++ FUN_001281-T1 6 SYERDCHEIVSTLVDHKILVGKQREMGLEKARILWTKAYPGEPFEVE---LNYPVFDVPSFESKIHYDIAQACSRQRVFYYQVSLPHYGDEKFLKN 98 69*******************************************99...444557889999********************************** PP GRDP-like 97 AvaRYkgFLyllkrnkeesskkflvPtyDidLiWhtHqlhpvsYakD 143 A++RYk++L l+++ +e flvP+yD+dLiWh+Hq++p++Y +D FUN_001281-T1 99 AAERYKHHLLLKQKDPE----AFLVPCYDFDLIWHAHQVQPIIYRND 141 ****************6....57*********************998 PP >> DUF6908 Domain of unknown function (DUF6908) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 0.64 8.2e+03 75 92 .. 3 20 .. 2 40 .. 0.70 2 ? -2.0 0.0 0.35 4.5e+03 41 51 .. 82 92 .. 73 95 .. 0.76 3 ? 11.6 0.1 2.2e-05 0.28 70 111 .. 130 170 .. 110 174 .. 0.80 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 0.64 DUF6908 75 eplyyrndylgieqesvk 92 p++y+ d +i + v+ FUN_001281-T1 3 SPISYERDCHEIVSTLVD 20 688888887777766655 PP == domain 2 score: -2.0 bits; conditional E-value: 0.35 DUF6908 41 lealsvaHYye 51 + ++s+ HY+ FUN_001281-T1 82 YYQVSLPHYGD 92 57899999986 PP == domain 3 score: 11.6 bits; conditional E-value: 2.2e-05 DUF6908 70 ggakleplyyrndylgieqesvkieeekevvlpklkaeleef 111 +++p+ yrnd l+i+ + +e++ v + l+++ e + FUN_001281-T1 130 AH-QVQPIIYRNDTLQIYYIEKQSTEGRCAVAEWLEQQTEVM 170 33.69***************9999999999888888887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 620 (0.0242709); expected 510.9 (0.02) Passed bias filter: 463 (0.0181249); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.34s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1879.82 // Query: FUN_001282-T1 [L=776] Description: FUN_001282 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-14 52.4 17.2 3.1e-07 31.0 2.5 3.9 3 DED Death effector domain ------ inclusion threshold ------ 0.061 13.6 0.6 0.33 11.2 0.0 2.5 2 TRADD-like_N TRADD-like N-terminal domain 0.076 13.9 0.1 0.58 11.1 0.0 2.3 2 ORF_12_N ORF 12 gene product N-terminal 0.12 13.0 0.1 0.12 13.0 0.1 3.6 4 DksA-like_N DnaK suppressor protein-like, N-terminal domain 0.14 11.9 0.1 0.21 11.3 0.1 1.2 1 DUF3187 Protein of unknown function (DUF3187) Domain annotation for each model (and alignments): >> DED Death effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.0 2.5 6.1e-11 3.1e-07 1 80 [. 6 83 .. 6 85 .. 0.93 2 ! 27.5 2.6 7.4e-10 3.8e-06 22 81 .. 112 172 .. 99 173 .. 0.88 3 ? 0.3 0.1 0.24 1.2e+03 17 63 .. 516 562 .. 513 565 .. 0.83 Alignments for each domain: == domain 1 score: 31.0 bits; conditional E-value: 6.1e-11 DED 1 frklLleiseeLtsee.lesLkFLlkdkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekyk 80 +++lLl+ise+L++ + l+ + F +++k+ e+i+++l++++ Le++g l+ d l+ ++++L+ + L ++i k++ FUN_001282-T1 6 YNSLLLRISERLDDINaLNRILFICREKL---AGENIHDSLSMLIKLEQKGFLGVDELQEVKDILKAVEEWGLREEIIKFE 83 789**********96549**********9...55899**************************************999987 PP == domain 2 score: 27.5 bits; conditional E-value: 7.4e-10 DED 22 FLlk.dkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 ++ ++ip+++ ++i+++++lf+ Le++ l+ d+l +L+e+L +++ ++Ll+++ +++k FUN_001282-T1 112 TVCRvKRIPEERKNDIHNLRSLFQVLEDMSFLGIDRLGILREILTELRNHELLTELAEFQK 172 4566355**************************************************9987 PP == domain 3 score: 0.3 bits; conditional E-value: 0.24 DED 17 lesLkFLlkdkipkrklekiksaldlfeeLekqgllsednldlLeel 63 l+++ +k+ p +k + k dl+ + ++l e++ ++Lee+ FUN_001282-T1 516 LRTIGIFFKKICPGSKISRLKPQFDLLHRQLESEHLHEEKEEILEEI 562 666666777778899999999999999999999*******9999997 PP >> TRADD-like_N TRADD-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.3 0.46 2.3e+03 36 60 .. 145 170 .. 143 171 .. 0.87 2 ? 11.2 0.0 6.5e-05 0.33 25 65 .. 254 294 .. 247 296 .. 0.87 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.46 TRADD-like_N 36 gsreeil.erllalynsGeLrellgl 60 ++r++il e l +l n L+el+ + FUN_001282-T1 145 IDRLGILrEILTELRNHELLTELAEF 170 79999999999999999999999765 PP == domain 2 score: 11.2 bits; conditional E-value: 6.5e-05 TRADD-like_N 25 ieeGSilvtfkgsreeilerllalynsGeLrellglsvete 65 i+eGS+++t++ + +le l ++y G+L+ l+ +++t+ FUN_001282-T1 254 ISEGSVCFTVRAETSLALEELYKRYSTGRLQRDLQEFLVTD 294 89****************************97666666665 PP >> ORF_12_N ORF 12 gene product N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00011 0.58 17 55 .. 375 413 .. 371 415 .. 0.91 2 ? -0.8 0.0 0.59 3e+03 5 37 .. 594 626 .. 591 636 .. 0.85 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00011 ORF_12_N 17 lnsdapiapadvaerfseeflaevpaeelaevlaqlraa 55 +++ +ia+++ +e++se l++++ e++ae++++lr + FUN_001282-T1 375 HSASSDIASEEPSEFTSEPCLKDLSEETIAELTNKLRFD 413 57789*******************************965 PP == domain 2 score: -0.8 bits; conditional E-value: 0.59 ORF_12_N 5 paGrqarwvldllnsdapiapadvaerfseefl 37 +++q+++v + l++++ + +ad+++ f+++ FUN_001282-T1 594 EIEKQLSQVNGDLQEKKKTIAADISNAFDKSWG 626 67889999999****9*********99998765 PP >> DksA-like_N DnaK suppressor protein-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.2 0.86 4.4e+03 36 50 .. 156 170 .. 152 176 .. 0.70 2 ? -2.0 0.8 1.1 5.7e+03 37 53 .. 313 329 .. 312 336 .. 0.78 3 ? -3.0 0.5 2.2 1.1e+04 38 51 .. 553 566 .. 547 568 .. 0.70 4 ? 13.0 0.1 2.3e-05 0.12 1 29 [. 584 612 .. 584 620 .. 0.88 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.86 DksA-like_N 36 vErendEVLeelGea 50 +E n E L el+e FUN_001282-T1 156 TELRNHELLTELAEF 170 577777777777765 PP == domain 2 score: -2.0 bits; conditional E-value: 1.1 DksA-like_N 37 ErendEVLeelGeagee 53 E+e E L++l ++++e FUN_001282-T1 313 EKEYREALDDLTNVDQE 329 67778999999999997 PP == domain 3 score: -3.0 bits; conditional E-value: 2.2 DksA-like_N 38 rendEVLeelGeag 51 e +E+Lee+ ++ FUN_001282-T1 553 EEKEEILEEIRYVE 566 46788888876555 PP == domain 4 score: 13.0 bits; conditional E-value: 2.3e-05 DksA-like_N 1 yekiLraRraelearLhkieddLdeprnk 29 ++ L++R+ e+e++L++++ dL+e+++ FUN_001282-T1 584 FKISLEKRKDEIEKQLSQVNGDLQEKKKT 612 6778********************99875 PP >> DUF3187 Protein of unknown function (DUF3187) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 4.1e-05 0.21 119 163 .. 322 366 .. 318 376 .. 0.90 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 4.1e-05 DUF3187 119 dlfgldQnGRdqaakgrlaiavprngikllnfsgetlgngalsvl 163 dl ++dQ+GRd+ +++++++ ++ + ++n+ ++t + + l + FUN_001282-T1 322 DLTNVDQEGRDDIEEKQSRYLNEERMAFVHNYLENTEDTSSLATG 366 7889******************************99998888766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (776 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1352 (0.0529262); expected 510.9 (0.02) Passed bias filter: 860 (0.0336661); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.45u 0.38s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 7303.14 // Query: FUN_001284-T1 [L=283] Description: FUN_001284 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (283 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 646 (0.0252887); expected 510.9 (0.02) Passed bias filter: 529 (0.0207086); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2858.15 // Query: FUN_001286-T1 [L=753] Description: FUN_001286 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-46 157.8 0.4 9.3e-39 133.9 0.3 2.3 2 GRDP-like Glycine-rich domain-containing protein-like ------ inclusion threshold ------ 0.2 11.5 0.0 0.36 10.7 0.0 1.3 1 DUF2113 Uncharacterized protein conserved in archaea (DUF2 Domain annotation for each model (and alignments): >> GRDP-like Glycine-rich domain-containing protein-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.0 2.3e-10 2.9e-06 64 143 .] 8 85 .. 1 85 [. 0.85 2 ! 133.9 0.3 7.3e-43 9.3e-39 1 143 [] 81 216 .. 81 216 .. 0.95 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 2.3e-10 GRDP-like 64 sikedLvsavkrqsefyyqvs.sphvseevfleeAvaRYkg.FLyllkrnkeesskkflvPtyDidLiWhtHqlhpvsYakD 143 +i+ dL++a++ +++f++ v+ +p + + +++A +RY+ +L l+ + + l +Di +Wh H l+p+sY +D FUN_001286-T1 8 HISVDLADAASSHRQFLKLVDeHPGLYNGPHVQNAIRRYELlWLPLIAQSSAA---D-LAAPLDIAWVWHVHMLSPISYERD 85 3899****************9789999************85367777777743...3.6667*****************998 PP == domain 2 score: 133.9 bits; conditional E-value: 7.3e-43 GRDP-like 1 sYkedceelfgkiidkkaidesneekalsrteelwkrlypeepfeleekklkakeeeveessssikedLvsavkrqsefyyqvssphvseevflee 96 sY++dc+e++++++d+k ++ +++ek l++++ lw++ yp epfe+e l+ v + +s+i++d+++a +rq+ fyyqvs ph+ +e+fl++ FUN_001286-T1 81 SYERDCHEIVSTLVDHKILVGKQREKGLEKARILWTKAYPGEPFEVE---LNYPVFDVPSFESKIHYDIAQACSRQRVFYYQVSLPHYGDEKFLKN 173 69*******************************************99...444557889999********************************** PP GRDP-like 97 AvaRYkgFLyllkrnkeesskkflvPtyDidLiWhtHqlhpvsYakD 143 A++RYk++L l+++ +e flvP+yD+dLiWh+Hq++p++Y +D FUN_001286-T1 174 AAERYKHHLLLKQKDPE----AFLVPCYDFDLIWHAHQVQPIIYRND 216 ****************6....57*********************998 PP >> DUF2113 Uncharacterized protein conserved in archaea (DUF2113) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 2.8e-05 0.36 74 144 .. 366 427 .. 355 436 .. 0.80 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 2.8e-05 DUF2113 74 kikiedEtYlpelLkkLwekygrdnveqpdRfeitiesdekleeieelvVadpseelkkklidaliriaPE 144 ++++ E Y+ + L++L ++ grd + p R e+ti++++k + ++ +++l+ +++++PE FUN_001286-T1 366 SLDVASEYYFLNYLDTL-SSSGRDATSDPVRHEVTINDEQKV---AFTT-----IAYQRRLLGYVFNVIPE 427 57899************.999*****************8744...3333.....34555566666666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (753 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 564 (0.0220787); expected 510.9 (0.02) Passed bias filter: 426 (0.0166765); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.35s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 7266.62 // Query: FUN_001287-T1 [L=780] Description: FUN_001287 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-12 48.5 18.7 3.4e-08 34.1 4.4 3.6 4 DED Death effector domain 0.0054 16.9 2.6 0.2 11.9 0.0 3.6 3 TRADD-like_N TRADD-like N-terminal domain ------ inclusion threshold ------ 0.2 12.5 0.1 0.45 11.3 0.1 1.5 1 CwsA Cell wall synthesis protein CwsA 0.46 11.0 8.6 17 5.9 0.1 3.1 2 Prefoldin_2 Prefoldin subunit 2.7 8.3 4.2 1.3 9.4 0.6 2.4 3 HrcA HrcA protein C terminal domain 3.2 8.2 5.0 1.1 9.7 0.5 2.7 3 Nas2_N Nas2 N_terminal domain 4.9 8.5 6.3 2.6 9.3 0.1 3.1 3 Occludin_ELL Occludin homology domain Domain annotation for each model (and alignments): >> DED Death effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 4.4 9.3e-12 3.4e-08 1 81 [. 6 87 .. 6 88 .. 0.96 2 ! 22.8 1.5 3.2e-08 0.00012 26 81 .. 120 175 .. 92 176 .. 0.87 3 ? -3.0 0.0 3.5 1.3e+04 50 66 .. 343 359 .. 340 362 .. 0.82 4 ? -2.5 0.0 2.5 9.1e+03 58 78 .. 454 474 .. 431 477 .. 0.69 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 9.3e-12 DED 1 frklLleiseeLtsee.lesLkFLlkdkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +++lL++is++L++ + le++ F +++k+ ++ ++i++ l+l++ Le+ g l+ d ++ ++++L+ dL +k+ k++ FUN_001287-T1 6 YKSLLFRISKRLDEINaLEHILFICEEKLERQADQDIHDTLSLLRKLEDSGFLGLDEMQEVKDILKAAEEWDLYEKVVKFES 87 789**********96549***********************************************************99986 PP == domain 2 score: 22.8 bits; conditional E-value: 3.2e-08 DED 26 dkipkrklekiksaldlfeeLekqgllsednldlLeelLrrikrkdLlkkiekykk 81 +ip+++ ++i+++++l++ Le+++ l+ d++ +L++++ +++ ++Ll+++ ++++ FUN_001287-T1 120 RRIPEERKNDIQDVRSLVQVLEDMNCLGIDRFGVLKKIFTELNNDELLTELAQFQE 175 469************************************************99986 PP == domain 3 score: -3.0 bits; conditional E-value: 3.5 DED 50 gllsednldlLeelLrr 66 l+e++l ++++ L++ FUN_001287-T1 343 RFLDEERLAFVQNYLEN 359 67999*****9999987 PP == domain 4 score: -2.5 bits; conditional E-value: 2.5 DED 58 dlLeelLrrikrkdLlkkiek 78 +lL +++r ++ dL++ +ek FUN_001287-T1 454 KLLIDFCRALQLYDLVEFLEK 474 778888888888888877665 PP >> TRADD-like_N TRADD-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.13 4.7e+02 45 60 .. 158 173 .. 148 174 .. 0.81 2 ! 11.9 0.0 5.4e-05 0.2 20 65 .. 252 297 .. 234 299 .. 0.81 3 ? 1.2 0.2 0.12 4.4e+02 3 26 .. 592 615 .. 590 616 .. 0.89 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.13 TRADD-like_N 45 llalynsGeLrellgl 60 + +l+n+ L+el+++ FUN_001287-T1 158 FTELNNDELLTELAQF 173 789**********998 PP == domain 2 score: 11.9 bits; conditional E-value: 5.4e-05 TRADD-like_N 20 illkdieeGSilvtfkgsreeilerllalynsGeLrellglsvete 65 i l i+eGS+++t++ + +le l ++y G+L+ l+ +++t+ FUN_001287-T1 252 IELRAISEGSVCFTVRAETSLALEELHKRYSTGRLQRDLQEFLVTD 297 556779*****************************97666666665 PP == domain 3 score: 1.2 bits; conditional E-value: 0.12 TRADD-like_N 3 tldrleslLaellgkdsillkdie 26 + d++e L +++g+ + + k+ie FUN_001287-T1 592 RKDEIEKELSQMSGDLQAKKKKIE 615 6899***********999999997 PP >> CwsA Cell wall synthesis protein CwsA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 0.00012 0.45 21 73 .. 257 311 .. 250 325 .. 0.80 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00012 CwsA 21 vtrGvvGlgvqsaqsta.aelrrryregrlarevaaaqea.laqelaaaqevvaa 73 ++ G v ++v++ s a +el +ry grl+r++ + + ++la +evv + FUN_001287-T1 257 ISEGSVCFTVRAETSLAlEELHKRYSTGRLQRDLQEFLVTdDIRQLANGEEVVVS 311 56778888888877766378************99986544156999999999975 PP >> Prefoldin_2 Prefoldin subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.1 0.0048 17 10 42 .. 78 110 .. 69 119 .. 0.83 2 ? 5.5 4.5 0.0062 23 64 93 .. 586 615 .. 582 617 .. 0.78 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0048 Prefoldin_2 10 lqqqlqqlaqqikqleeqlkelelvleelelld 42 l +++ ++++ + +++e l+++ +vleel++l+ FUN_001287-T1 78 LYEKVVKFESRRSEYKELLERVIDVLEELNDLE 110 778899999999999999999999999999987 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0062 Prefoldin_2 64 keeLeerketlekeiktlekqleklekele 93 k+eLe+rk+++eke+++++ l+ ++k++e FUN_001287-T1 586 KTELEKRKDEIEKELSQMSGDLQAKKKKIE 615 678888888888888888888888888876 PP >> HrcA HrcA protein C terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.6 0.00034 1.3 98 157 .. 85 144 .. 60 206 .. 0.79 2 ? -3.3 0.1 2.7 9.7e+03 127 158 .. 330 362 .. 276 374 .. 0.61 3 ? -2.8 0.0 1.9 7e+03 141 164 .. 720 746 .. 712 756 .. 0.73 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00034 HrcA 98 lkeeleeldelleavlealeealseeee..lyvsGtsnlleqpefsddeklrellelleeke 157 +++++e++elle+v+++lee+ + e+ + v+ ++++ e+ + +d++++r+l+++le+ + FUN_001287-T1 85 FESRRSEYKELLERVIDVLEELNDL-ERlmCTVGRVRRIPEERK-NDIQDVRSLVQVLEDMN 144 355677999*********9888773.334255555555555555.688***********974 PP == domain 2 score: -3.3 bits; conditional E-value: 2.7 HrcA 127 yvsGtsnll.eqpefsddeklrellelleekee 158 +G+ + +q+ f d e+l + + le+ ++ FUN_001287-T1 330 NQEGRDDIEkKQSRFLDEERLAFVQNYLENTDD 362 344444444345555555666666666666555 PP == domain 3 score: -2.8 bits; conditional E-value: 1.9 HrcA 141 sddeklrellelleekeellell...e 164 d +l ++le+l ++ ++l+l+ + FUN_001287-T1 720 GDEGTLSTILEVLSKRWQILDLIsivK 746 455889999999999999999984431 PP >> Nas2_N Nas2 N_terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.1 3.4 1.2e+04 6 24 .. 87 105 .. 84 109 .. 0.65 2 ? -3.4 0.0 3.6 1.3e+04 9 22 .. 127 140 .. 119 146 .. 0.53 3 ? 9.7 0.5 0.00029 1.1 3 29 .. 588 614 .. 586 621 .. 0.86 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 3.4 Nas2_N 6 akkkeleaeleelsevLes 24 +++e ++ le++ +vLe+ FUN_001287-T1 87 SRRSEYKELLERVIDVLEE 105 5666667777777777764 PP == domain 2 score: -3.4 bits; conditional E-value: 3.6 Nas2_N 9 keleaeleelsevL 22 k+ +++++l +vL FUN_001287-T1 127 KNDIQDVRSLVQVL 140 33334445555555 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00029 Nas2_N 3 eLqakkkeleaeleelsevLesqgvgm 29 eL+++k+e+e+el+++s L++++ ++ FUN_001287-T1 588 ELEKRKDEIEKELSQMSGDLQAKKKKI 614 89*******************776655 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 3.4 1.3e+04 23 51 .. 5 33 .. 4 55 .. 0.59 2 ? 9.3 0.1 0.00072 2.6 16 56 .. 84 131 .. 67 186 .. 0.71 3 ? 1.0 0.3 0.29 1.1e+03 53 81 .. 585 613 .. 569 621 .. 0.68 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 3.4 Occludin_ELL 23 eYkeLhaeleavskkfskleeelkslkeg 51 eYk+L ++ + ++++ le+ l +e+ FUN_001287-T1 5 EYKSLLFRISKRLDEINALEHILFICEEK 33 78888877777777777777655444333 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00072 Occludin_ELL 16 eFnaeykeYkeLhaeleavskkfskle......eelkslkegsk.eyk 56 +F++ +eYkeL +++ +v +++++le ++++++e++k ++ FUN_001287-T1 84 KFESRRSEYKELLERVIDVLEELNDLErlmctvGRVRRIPEERKnDIQ 131 699999*********************444444344444444443333 PP == domain 3 score: 1.0 bits; conditional E-value: 0.29 Occludin_ELL 53 k..eykkiaeeilqeykklkkdpeylekkkr 81 k e +k+++ei +e++++ + + ++kkk+ FUN_001287-T1 585 KktELEKRKDEIEKELSQM--SGDLQAKKKK 613 3347788888888888888..4444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (780 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1556 (0.0609121); expected 510.9 (0.02) Passed bias filter: 918 (0.0359366); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.41 # Mc/sec: 7705.90 // Query: FUN_001288-T1 [L=908] Description: FUN_001288 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-45 155.5 0.7 2.7e-38 132.4 0.5 2.4 2 GRDP-like Glycine-rich domain-containing protein-like ------ inclusion threshold ------ 0.14 12.9 0.1 0.36 11.5 0.0 1.6 2 VMAP-M9 vWA-MoxR associated protein middle region (VMAP-M) Domain annotation for each model (and alignments): >> GRDP-like Glycine-rich domain-containing protein-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 5e-10 6.4e-06 64 143 .] 8 85 .. 1 85 [. 0.85 2 ! 132.4 0.5 2.1e-42 2.7e-38 1 143 [] 81 216 .. 81 216 .. 0.95 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 5e-10 GRDP-like 64 sikedLvsavkrqsefyyqvs.sphvseevfleeAvaRYkg.FLyllkrnkeesskkflvPtyDidLiWhtHqlhpvsYakD 143 +i+ dLv+a+ +++f++ v+ +p + +++A +RY+ +L l+ + + ++ +Di +Wh H l+p sY +D FUN_001288-T1 8 QISVDLVHAALAHRQFLKLVDeHPGLYAGPHIQNAIRRYELlWLPLIAQSSAA----TVAAPLDIAWVWHVHMLSPLSYERD 85 4899****************9789999999*********85367788777754....36667*****************998 PP == domain 2 score: 132.4 bits; conditional E-value: 2.1e-42 GRDP-like 1 sYkedceelfgkiidkkaidesneekalsrteelwkrlypeepfeleekklkakeeeveessssikedLvsavkrqsefyyqvssphvseevflee 96 sY++dc+e++++++d+k ++ +++k l++++ lw++ yp epfe+e l++ + v + +s+i++d+++a +rq+ fyyqvs ph+ +e+fl++ FUN_001288-T1 81 SYERDCHEIVSTLVDHKILVGWQRDKGLEKARILWTKAYPGEPFEVE---LNNPDFDVPSFESKIHYDIAQACSRQRVFYYQVSLPHYGNEKFLKN 173 69*******************************************99...444557889999********************************** PP GRDP-like 97 AvaRYkgFLyllkrnkeesskkflvPtyDidLiWhtHqlhpvsYakD 143 Av+RYk++L l+++ +e+ f vP+yD+dLiWh+Hq++p++Y +D FUN_001288-T1 174 AVERYKHHLLLKQKHPED----FFVPCYDFDLIWHAHQVQPIIYRND 216 ****************76....69********************998 PP >> VMAP-M9 vWA-MoxR associated protein middle region (VMAP-M) 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 2.8e-05 0.36 58 123 .. 304 369 .. 295 375 .. 0.88 2 ? -3.5 0.1 1.2 1.6e+04 15 33 .. 488 506 .. 482 516 .. 0.78 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 2.8e-05 VMAP-M9 58 ksylldndnanfeeiidkiinlpddkdllrilfrltqdsrinsynrsyieqtiqelkkllnitdtd 123 ksy ++ d an e +i+k ++ p + frl+ r y ++t +kk l+++ FUN_001288-T1 304 KSYTVQMDFANGERVINKTVKGPAADVRVSSTFRLSTSRSRSLKVRVYRNKTCSCFKKSLDVASEY 369 9***********************999999*****86544455679**************998655 PP == domain 2 score: -3.5 bits; conditional E-value: 1.2 VMAP-M9 15 naidnkgisvensfvkskt 33 + i+n+gi v + v s FUN_001288-T1 488 EIINNNGIVVSTAHVVSGD 506 579999**99999988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (908 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 629 (0.0246232); expected 510.9 (0.02) Passed bias filter: 422 (0.0165199); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.43 # Mc/sec: 8600.87 // Query: FUN_001288-T2 [L=833] Description: FUN_001288 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-38 133.3 0.6 2.6e-38 132.4 0.6 1.5 1 GRDP-like Glycine-rich domain-containing protein-like ------ inclusion threshold ------ 0.12 13.1 0.1 0.32 11.6 0.0 1.7 2 VMAP-M9 vWA-MoxR associated protein middle region (VMAP-M) Domain annotation for each model (and alignments): >> GRDP-like Glycine-rich domain-containing protein-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.4 0.6 2e-42 2.6e-38 1 143 [] 6 141 .. 6 141 .. 0.95 Alignments for each domain: == domain 1 score: 132.4 bits; conditional E-value: 2e-42 GRDP-like 1 sYkedceelfgkiidkkaidesneekalsrteelwkrlypeepfeleekklkakeeeveessssikedLvsavkrqsefyyqvssphvseevflee 96 sY++dc+e++++++d+k ++ +++k l++++ lw++ yp epfe+e l++ + v + +s+i++d+++a +rq+ fyyqvs ph+ +e+fl++ FUN_001288-T2 6 SYERDCHEIVSTLVDHKILVGWQRDKGLEKARILWTKAYPGEPFEVE---LNNPDFDVPSFESKIHYDIAQACSRQRVFYYQVSLPHYGNEKFLKN 98 69*******************************************99...444557889999********************************** PP GRDP-like 97 AvaRYkgFLyllkrnkeesskkflvPtyDidLiWhtHqlhpvsYakD 143 Av+RYk++L l+++ +e+ f vP+yD+dLiWh+Hq++p++Y +D FUN_001288-T2 99 AVERYKHHLLLKQKHPED----FFVPCYDFDLIWHAHQVQPIIYRND 141 ****************76....69********************998 PP >> VMAP-M9 vWA-MoxR associated protein middle region (VMAP-M) 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 2.5e-05 0.32 58 123 .. 229 294 .. 220 300 .. 0.88 2 ? -3.3 0.1 1 1.3e+04 15 33 .. 413 431 .. 406 441 .. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.5e-05 VMAP-M9 58 ksylldndnanfeeiidkiinlpddkdllrilfrltqdsrinsynrsyieqtiqelkkllnitdtd 123 ksy ++ d an e +i+k ++ p + frl+ r y ++t +kk l+++ FUN_001288-T2 229 KSYTVQMDFANGERVINKTVKGPAADVRVSSTFRLSTSRSRSLKVRVYRNKTCSCFKKSLDVASEY 294 9***********************999999*****86544455679**************998655 PP == domain 2 score: -3.3 bits; conditional E-value: 1 VMAP-M9 15 naidnkgisvensfvkskt 33 + i+n+gi v + v s FUN_001288-T2 413 EIINNNGIVVSTAHVVSGD 431 679999**99999988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (833 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 828 (0.0324134); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 7980.52 // Query: FUN_001289-T1 [L=1111] Description: FUN_001289 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-63 211.5 1.8 9.5e-63 210.6 1.8 1.5 1 GBD-like_ZMIZ1_ZMIZ2 ZMIZ1/ZMIZ2 GBD-like domain 2.4e-40 137.4 0.0 4.5e-40 136.5 0.0 1.5 1 Zmiz1_N Zmiz1 N-terminal tetratricopeptide repe 3.4e-21 75.2 3.7 3.4e-21 75.2 3.7 2.4 2 zf-MIZ MIZ/SP-RING zinc finger 1.8e-05 24.9 1.3 1.8e-05 24.9 1.3 2.5 3 zf-Nse Zinc-finger of the MIZ type in Nse subu Domain annotation for each model (and alignments): >> GBD-like_ZMIZ1_ZMIZ2 ZMIZ1/ZMIZ2 GBD-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 210.6 1.8 1.5e-66 9.5e-63 2 126 .] 624 748 .. 623 748 .. 0.99 Alignments for each domain: == domain 1 score: 210.6 bits; conditional E-value: 1.5e-66 GBD-like_ZMIZ1_ZMIZ2 2 rltfpvrdgvvlepFrLehnlavsnhvFslkeevfntLmlredlelqlkcfhhedrqmktnwPasvsvsvnatsltierkekksgkdkP 90 rltfpvrdg+vl+pFrLehnlavsnhvF+l+++v++tLm+r+dlelq+kc+hhed+qm+tnwPasv+vsvna++l ier+ ++++++kP FUN_001289-T1 624 RLTFPVRDGIVLPPFRLEHNLAVSNHVFHLRDSVHQTLMMRPDLELQFKCYHHEDKQMYTNWPASVTVSVNANPLMIERQGDNKTSHKP 712 89*************************************************************************************** PP GBD-like_ZMIZ1_ZMIZ2 91 lelkkllqpgrntiqitvtacacshlFvlqlvhRps 126 l+lk++++pgrntiqitvtac+cshlFvlqlvhRps FUN_001289-T1 713 LHLKNVCKPGRNTIQITVTACCCSHLFVLQLVHRPS 748 **********************************97 PP >> Zmiz1_N Zmiz1 N-terminal tetratricopeptide repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 136.5 0.0 7e-44 4.5e-40 1 99 [] 9 107 .. 9 107 .. 0.99 Alignments for each domain: == domain 1 score: 136.5 bits; conditional E-value: 7e-44 Zmiz1_N 1 vqqnnerllsikeslqeertfekaatelldwcgdsrafsrsfeenllavlqvvvevatkdGfdlelayrllavcaanrkllskksaakinrwfeql 96 +qq+nerl++ik++l +++f+ +a+ell+wcgd raf+r+fe nl+++l+vv++va G+dl+l+yrlla+caa+r++++ ksa + w+e+l FUN_001289-T1 9 IQQTNERLQCIKQHLSTPQGFQTSARELLEWCGDVRAFQRAFESNLMGCLTVVSQVAPSPGYDLDLGYRLLAICAAHRDKFTSKSANMLGVWCEDL 104 8*********************************************************************************************** PP Zmiz1_N 97 krl 99 +rl FUN_001289-T1 105 GRL 107 996 PP >> zf-MIZ MIZ/SP-RING zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 1.0 0.26 1.6e+03 4 24 .. 718 738 .. 715 743 .. 0.87 2 ! 75.2 3.7 5.4e-25 3.4e-21 1 49 [. 796 844 .. 796 845 .. 0.98 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.26 zf-MIZ 4 kCplsksrikiPvrgkkCkHl 24 C + i+i v ++ C+Hl FUN_001289-T1 718 VCKPGRNTIQITVTACCCSHL 738 68888899************7 PP == domain 2 score: 75.2 bits; conditional E-value: 5.4e-25 zf-MIZ 1 vslkCplsksrikiPvrgkkCkHlqCfdllsylelqertptWnCPvCdk 49 vslkCp++++ri++P+rg+ CkH+qCfdl+syl+l++ + +W+CPvC+k FUN_001289-T1 796 VSLKCPITFRRITLPARGHDCKHIQCFDLESYLRLNCDRGSWKCPVCSK 844 79*********************************************97 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.1 0.91 5.8e+03 3 36 .. 644 679 .. 643 684 .. 0.70 2 ? -2.7 0.5 1.3 8e+03 14 34 .. 711 739 .. 698 740 .. 0.68 3 ! 24.9 1.3 2.9e-09 1.8e-05 8 57 .] 794 843 .. 787 843 .. 0.89 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.91 zf-Nse 3 laieeekislkcPltlqpfkePvtsk..kCnHvfek 36 la+++ ++ l++ + + + +P + kC H+ +k FUN_001289-T1 644 LAVSNHVFHLRDSVHQTLMMRPDLELqfKCYHHEDK 679 677778888888888888888865433488887666 PP == domain 2 score: -2.7 bits; conditional E-value: 1.3 zf-Nse 14 cPltlqpfkePvtsk........kCnHvf 34 Pl l+++ +P +++ C H f FUN_001289-T1 711 KPLHLKNVCKPGRNTiqitvtacCCSHLF 739 57777777777777766666666889987 PP == domain 3 score: 24.9 bits; conditional E-value: 2.9e-09 zf-Nse 8 ekislkcPltlqpfkePvtskkCnHv..fekeaIlellkrkkkvkCPvvgCs 57 k+slkcP+t++ ++ P + + C+H+ f+ e+ l+l + + kCPv Cs FUN_001289-T1 794 IKVSLKCPITFRRITLPARGHDCKHIqcFDLESYLRLNCDRGSWKCPV--CS 843 5789*********************76699999999999*********..86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1111 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3758 (0.147113); expected 510.9 (0.02) Passed bias filter: 1175 (0.0459973); expected 510.9 (0.02) Passed Vit filter: 188 (0.00735956); expected 25.5 (0.001) Passed Fwd filter: 23 (0.000900372); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.69u 0.43s 00:00:01.11 Elapsed: 00:00:00.45 # Mc/sec: 10012.71 // Query: FUN_001290-T1 [L=535] Description: FUN_001290 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-57 193.9 0.2 8.2e-53 180.1 0.0 2.2 2 ELFV_dehydrog Glutamate/Leucine/Phenylalanine/Valine dehyd 3.1e-51 172.9 0.0 5.9e-51 172.0 0.0 1.4 1 ELFV_dehydrog_N Glu/Leu/Phe/Val dehydrogenase, dimerisation 0.00053 19.1 0.0 0.37 9.7 0.0 2.1 2 Bac_GDH_CD Bacterial NAD-glutamate dehydrogenase, catal ------ inclusion threshold ------ 0.037 13.9 0.0 0.17 11.7 0.0 1.9 2 2-Hacid_dh_C D-isomer specific 2-hydroxyacid dehydrogenas 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 KR KR domain 0.16 12.5 0.1 0.4 11.3 0.1 1.6 1 AdoHcyase_NAD S-adenosyl-L-homocysteine hydrolase, NAD bin Domain annotation for each model (and alignments): >> ELFV_dehydrog Glutamate/Leucine/Phenylalanine/Valine dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 180.1 0.0 1.9e-56 8.2e-53 1 191 [. 243 431 .. 243 460 .. 0.91 2 ! 11.9 0.0 4.4e-05 0.19 193 242 .] 480 531 .. 467 531 .. 0.87 Alignments for each domain: == domain 1 score: 180.1 bits; conditional E-value: 1.9e-56 ELFV_dehydrog 1 GGslgreeaTgyGvvyfveealkklkle.......slegkrvavsGsGnvgsyaaellselgakvvavsDssGviydeeGldleellelkeerksv 89 GG++gr aTg+Gv++ +++ +++ k l+gk+++v+G+Gnvg ++++ l+++ga++++v + +G +y+e+G+d +el ++k +++s+ FUN_001290-T1 243 GGIHGRISATGRGVFHGIDNFISSEKYAkfvglepGLTGKTFIVQGFGNVGLHTCRYLHRAGARCIGVMERDGNLYNEDGIDPKELEDYKLDNGSI 338 9***************999988875555566666889*********************************************************** PP ELFV_dehydrog 90 keyaksekkaeyieneeellelkvdilvPaAtqneineenaktlikngaklvvEgANmpttpeAdeileekgvlvvpdkaaNaGGVtvSylEmvqn 185 k ++ + a ++++e +lle ++dilvPaA +++i+ +na +ik ak+++EgAN+pttp+A++il e++ lv+pd + NaGGVtvSy+E+++n FUN_001290-T1 339 KGFP--G--A-KMTEE-NLLEAECDILVPAANEKQITIKNAP-NIK--AKVIAEGANGPTTPAAERILIENKKLVIPDLYLNAGGVTVSYFEWLKN 425 ****..4..3.55554.8************************.***..************************************************ PP ELFV_dehydrog 186 lqrlsw 191 ++++s+ FUN_001290-T1 426 INHVSF 431 998765 PP == domain 2 score: 11.9 bits; conditional E-value: 4.4e-05 ELFV_dehydrog 193 eeevdeklkeimkeafeavveeaeeykve..lrkaaniagfekvaeamkarG 242 ++ v++ l+ m++ +++++ aeey+ +r+aa+i+++ekv + a G FUN_001290-T1 480 RDIVHSGLEFTMERSAKQIMRCAEEYNLGldIRTAAYIVSMEKVYNTYAAAG 531 566888999*****************99888*************99887766 PP >> ELFV_dehydrog_N Glu/Leu/Phe/Val dehydrogenase, dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 172.0 0.0 1.4e-54 5.9e-51 4 128 .. 95 221 .. 93 222 .. 0.98 Alignments for each domain: == domain 1 score: 172.0 bits; conditional E-value: 1.4e-54 ELFV_dehydrog_N 4 vlevrvpvkmddgevevlkgyrvqhntalgPakGGirfhpevneeevkaLaalmtlKnalvglplGGgkggikvdpkklseeelerltrrfvee 97 vl+v +pvk+d+g +e+++gyr+qh+++++P+kGGir++++v+ +ev+aLa+lmt+K+a+v++p+GG+kggik+ p+++s+ ele++trrf+ e FUN_001290-T1 95 VLSVVFPVKRDNGAFELIQGYRAQHSHHRTPCKGGIRYSDDVDIDEVQALATLMTFKCAVVDVPFGGAKGGIKIKPSQYSQVELEKITRRFTVE 188 78999***************************************************************************************** PP ELFV_dehydrog_N 98 la..rligpdkDvpApDvgtgeremawiadeys 128 la ++igp DvpApD+gtge+em+wiad ++ FUN_001290-T1 189 LAkkNFIGPGLDVPAPDMGTGEKEMSWIADSFD 221 **99*************************9875 PP >> Bac_GDH_CD Bacterial NAD-glutamate dehydrogenase, catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.0 0.0005 2.1 84 140 .. 125 182 .. 109 206 .. 0.73 2 ! 9.7 0.0 8.6e-05 0.37 396 448 .. 369 422 .. 352 461 .. 0.78 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0005 Bac_GDH_CD 84 varGGlrwsdrredfrtevlGlvkaqqvknavi.vPv.GakGGfvvkklp.kaadreall 140 +GG+r+sd + ev l + k av+ vP GakGG +k + ++ + e+++ FUN_001290-T1 125 PCKGGIRYSDDVD--IDEVQALATLMTFKCAVVdVPFgGAKGGIKIKPSQySQVELEKIT 182 579*******876..4699999999999*99987998469***99987663445555544 PP == domain 2 score: 9.7 bits; conditional E-value: 8.6e-05 Bac_GDH_CD 396 rv.ngaelrakvvgeGgnlgltqlgrieyalkggrintdaidnsaGvdcsdhev 448 + n+ +++akv++eG+n t ++ + +++ + d n++Gv +s e FUN_001290-T1 369 TIkNAPNIKAKVIAEGANGPTTPAAERILIENKKLVIPDLYLNAGGVTVSYFEW 422 4437889***********9999988777788889999************98884 PP >> 2-Hacid_dh_C D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 0.35 1.5e+03 73 105 .. 74 106 .. 67 109 .. 0.71 2 ? 11.7 0.0 3.9e-05 0.17 21 69 .. 267 314 .. 251 332 .. 0.74 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.35 2-Hacid_dh_C 73 eeaeelgvelv.sldellaesDvvslhlpltket 105 + +e+++ + +ld + +Dv+s++ p++ ++ FUN_001290-T1 74 K-FEDKKHRIKgTLDVMKPCADVLSVVFPVKRDN 106 3.444444444489999999*********98765 PP == domain 2 score: 11.7 bits; conditional E-value: 3.9e-05 2-Hacid_dh_C 21 gkwksekkllgkelsgktvGiiGlGrIGravakrlkafgmkviaydrsr 69 +k+ ++ l l+gkt + G+G++G ++ + l+ g++ i++ + FUN_001290-T1 267 EKY-AKFVGLEPGLTGKTFIVQGFGNVGLHTCRYLHRAGARCIGVMERD 314 555.33344445799****************************987664 PP >> KR KR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 5.1e-05 0.22 3 42 .. 283 322 .. 281 365 .. 0.84 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 5.1e-05 KR 3 ylitGGlGgLGrelarwLaekGarhlvllsrsaaasedae 42 +i+ G+G+ G++++r+L + Gar + ++ r+++ +++ FUN_001290-T1 283 TFIVQGFGNVGLHTCRYLHRAGARCIGVMERDGNLYNEDG 322 567778*************************986655554 PP >> AdoHcyase_NAD S-adenosyl-L-homocysteine hydrolase, NAD binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 9.4e-05 0.4 21 50 .. 279 308 .. 276 316 .. 0.90 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 9.4e-05 AdoHcyase_NAD 21 iaGkvavvaGyGdvGkGcaaslkglGarvi 50 ++Gk+ +v G+G+vG +++ l+ +Gar i FUN_001290-T1 279 LTGKTFIVQGFGNVGLHTCRYLHRAGARCI 308 68*************************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (535 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 686 (0.0268546); expected 510.9 (0.02) Passed bias filter: 674 (0.0263848); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5297.39 // Query: FUN_001291-T1 [L=245] Description: FUN_001291 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (245 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 689 (0.026972); expected 510.9 (0.02) Passed bias filter: 452 (0.0176943); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 2521.45 // Query: FUN_001292-T1 [L=601] Description: FUN_001292 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0003 21.5 0.1 0.6 10.9 0.0 3.2 3 ZU5 ZU5 domain ------ inclusion threshold ------ 0.036 14.3 0.1 0.075 13.3 0.1 1.4 1 V-set_CD47 CD47 immunoglobulin-like domain 0.25 12.2 0.9 0.59 11.0 0.7 1.8 2 Zn_ribbon_ISL3 zinc-finger of transposase IS204/IS1001/IS109 Domain annotation for each model (and alignments): >> ZU5 ZU5 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.5 0.0 0.0016 14 8 78 .. 8 79 .. 1 98 [. 0.75 2 ? -0.6 0.0 0.27 2.3e+03 17 48 .. 167 198 .. 162 210 .. 0.86 3 ! 10.9 0.0 7.1e-05 0.6 54 81 .. 231 258 .. 217 279 .. 0.83 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0016 ZU5 8 rGgrlvlp.ntgvsllvPegaipegtrieiylavlkkesslpkleegetllspvvecGPsglkfskpvilev 78 +G+ ++ gv++ v + + ++++ + +k ++ p lee+e +s ++++ P++ f+ p +l + FUN_001292-T1 8 AGCMRAGQeFLGVNFKVSRTLERNVELRNVKIRIINKFQYEPFLEENEKRISDIIQIYPKEFVFNPPAELVI 79 555555554456666665544444445567778888999999***********************9987755 PP == domain 2 score: -0.6 bits; conditional E-value: 0.27 ZU5 17 tgvsllvPegaipegtrieiylavlkkesslp 48 g+++ +P g +++++++++ + +++ +s p FUN_001292-T1 167 KGIQIKFPIGCVAKKMSVTLQTISSDELCSEP 198 699****************9999998887776 PP == domain 3 score: 10.9 bits; conditional E-value: 7.1e-05 ZU5 54 etllspvvecGPsglkfskpvilevpHc 81 ++ spvv + Ps ++f++pv+l++ FUN_001292-T1 231 DVTSSPVVLIRPSRYRFLRPVQLTLALL 258 6778*******************99755 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 8.8e-06 0.075 12 89 .. 76 146 .. 68 154 .. 0.81 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 8.8e-06 V-set_CD47 12 qlvfnnvksveytvCndtvvieCdvdnleyknisevyvkWkfnnkdifisnktekkstLkldfsdalsGnYtCevtel 89 +lv++ + v C ++v i C+ +++y+ y+kW++ +++ f n ++++ ++ + sG Yt +vt++ FUN_001292-T1 76 ELVIKLPSCVGPQSCGQMVCIYCSNRSMRYSA---KYLKWRLLDSHCFFVNVSRTEARIICK----RSGLYTIKVTQQ 146 67777777888899****************95...5*************9999888866654....568888887766 PP >> Zn_ribbon_ISL3 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 3 2.6e+04 19 36 .. 35 52 .. 35 57 .. 0.78 2 ? 11.0 0.7 7e-05 0.59 3 45 .. 93 134 .. 91 135 .. 0.79 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 3 Zn_ribbon_ISL3 19 rerkvrdLdiggkrviLr 36 r +k+r + ++ + +L+ FUN_001292-T1 35 RNVKIRIINKFQYEPFLE 52 578999999999988886 PP == domain 2 score: 11.0 bits; conditional E-value: 7e-05 Zn_ribbon_ISL3 3 irCPeCgrktkrvhgrrerkvrdLdiggkrviLrlrkrRykCk 45 ++C +C ++++r + k+r Ld +++ v + R++Ck FUN_001292-T1 93 MVCIYCSNRSMRYSA-KYLKWRLLDSHCFFVNVSRTEARIICK 134 79*******655555.47*********9988777777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (601 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 645 (0.0252496); expected 510.9 (0.02) Passed bias filter: 544 (0.0212958); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 5800.45 // Query: FUN_001294-T1 [L=287] Description: FUN_001294 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (287 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 559 (0.021883); expected 510.9 (0.02) Passed bias filter: 503 (0.0196907); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2815.58 // Query: FUN_001295-T1 [L=446] Description: FUN_001295 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-23 78.9 24.3 6.8e-05 23.1 0.1 8.6 8 LRR_6 Leucine Rich repeat 5.2e-13 46.9 10.9 4 8.5 0.1 8.8 8 LRR_1 Leucine Rich Repeat 1.1e-05 26.2 0.2 5.5e-05 23.9 0.1 2.4 2 EF-hand_7 EF-hand domain pair 1.8e-05 24.4 0.3 5e-05 23.1 0.3 1.8 1 EF-hand_1 EF hand domain 0.00032 20.5 0.2 0.00089 19.1 0.2 1.7 1 EF-hand_5 EF hand 0.00036 21.2 27.1 0.015 16.0 0.6 5.7 7 LRR_4 Leucine Rich repeats (2 copies) 0.0005 20.1 0.1 0.0026 17.8 0.1 2.3 1 EF-hand_6 EF-hand domain 0.00082 19.6 27.7 1.1 9.5 1.2 6.7 6 LRR_8 Leucine rich repeat 0.0094 16.2 0.5 1.1 9.5 0.1 2.5 2 DUF2202 Uncharacterized protein domain (DUF2202) ------ inclusion threshold ------ 0.017 15.3 1.3 0.032 14.4 0.4 2.0 2 EF-hand_8 EF-hand domain pair 1.1 9.7 5.0 0.7 10.3 0.2 2.7 2 LRR_R13L1-DRL21 R13L1/DRL21 LRRs Domain annotation for each model (and alignments): >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.15 3.5e+02 7 23 .. 90 106 .. 85 107 .. 0.83 2 ! 20.3 0.2 2.3e-07 0.00053 2 24 .] 113 135 .. 112 135 .. 0.94 3 ! 14.2 0.2 2.1e-05 0.048 1 24 [] 140 163 .. 140 163 .. 0.92 4 ? 1.0 0.0 0.35 8.1e+02 7 16 .. 174 183 .. 168 190 .. 0.79 5 ! 10.8 0.0 0.00026 0.6 1 19 [. 196 214 .. 196 219 .. 0.78 6 ! 15.2 0.2 9.7e-06 0.023 1 19 [. 224 242 .. 224 247 .. 0.87 7 ! 23.1 0.1 2.9e-08 6.8e-05 2 24 .] 253 275 .. 252 275 .. 0.95 8 ? 3.1 0.2 0.076 1.8e+02 4 13 .. 283 292 .. 281 294 .. 0.90 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.15 LRR_6 7 eLdLsgNdIgDeGleaL 23 +L++++N+++ e ++++ FUN_001295-T1 90 KLNIAHNELSIESGKCI 106 69******987777776 PP == domain 2 score: 20.3 bits; conditional E-value: 2.3e-07 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n+ LteL+L++N+I eG++a+a FUN_001295-T1 113 NRALTELNLANNNIRKEGIIAIA 135 888*******************8 PP == domain 3 score: 14.2 bits; conditional E-value: 2.1e-05 LRR_6 1 hnttLteLdLsgNdIgDeGleaLa 24 hn t+++LdL+ N++gD+ + La FUN_001295-T1 140 HNDTIRKLDLARNGLGDSDARLLA 163 7889**************998886 PP == domain 4 score: 1.0 bits; conditional E-value: 0.35 LRR_6 7 eLdLsgNdIg 16 ++Ls+N+++ FUN_001295-T1 174 IVNLSYNNFS 183 68*****986 PP == domain 5 score: 10.8 bits; conditional E-value: 0.00026 LRR_6 1 hnttLteLdLsgNdIgDeG 19 +n++L eLdLs+N I G FUN_001295-T1 196 YNNSLLELDLSWNFIRRAG 214 69***********776555 PP == domain 6 score: 15.2 bits; conditional E-value: 9.7e-06 LRR_6 1 hnttLteLdLsgNdIgDeG 19 +n++L++L+Ls+N+++D G FUN_001295-T1 224 YNSSLEKLNLSWNGLDDCG 242 69*************9966 PP == domain 7 score: 23.1 bits; conditional E-value: 2.9e-08 LRR_6 2 nttLteLdLsgNdIgDeGleaLa 24 n+t++eLd+s+N+I+D+Gl+ +a FUN_001295-T1 253 NSTIKELDISNNRISDKGLINIA 275 99*****************9997 PP == domain 8 score: 3.1 bits; conditional E-value: 0.076 LRR_6 4 tLteLdLsgN 13 +L++L++s+N FUN_001295-T1 283 KLEVLNVSHN 292 69*******9 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.24 5.6e+02 4 20 .. 90 106 .. 88 109 .. 0.74 2 ! 8.5 0.0 0.0018 4.2 2 16 .. 116 130 .. 115 136 .. 0.78 3 ? 3.8 0.0 0.067 1.6e+02 2 16 .. 144 158 .. 143 164 .. 0.79 4 ? 4.5 0.1 0.039 92 2 16 .. 172 186 .. 171 192 .. 0.74 5 ? 4.3 0.0 0.046 1.1e+02 1 14 [. 199 212 .. 199 221 .. 0.78 6 ! 7.2 0.1 0.0047 11 1 14 [. 227 240 .. 227 251 .. 0.79 7 ! 8.5 0.1 0.0017 4 2 16 .. 256 270 .. 255 275 .. 0.80 8 ? 5.7 0.0 0.015 35 1 15 [. 283 297 .. 283 302 .. 0.83 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.24 LRR_1 4 eLdLsnNnlsgllpesl 20 +L++++N ls ++ ++ FUN_001295-T1 90 KLNIAHNELSIESGKCI 106 79*******86655555 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0018 LRR_1 2 LeeLdLsnNnlsgll 16 L+eL+L+nNn+ + FUN_001295-T1 116 LTELNLANNNIRKEG 130 99*********6544 PP == domain 3 score: 3.8 bits; conditional E-value: 0.067 LRR_1 2 LeeLdLsnNnlsgll 16 +++LdL++N l++++ FUN_001295-T1 144 IRKLDLARNGLGDSD 158 689********7655 PP == domain 4 score: 4.5 bits; conditional E-value: 0.039 LRR_1 2 LeeLdLsnNnlsgll 16 L +++Ls+Nn+s+ + FUN_001295-T1 172 LFIVNLSYNNFSEAS 186 6789*******8655 PP == domain 5 score: 4.3 bits; conditional E-value: 0.046 LRR_1 1 nLeeLdLsnNnlsg 14 +L eLdLs N + FUN_001295-T1 199 SLLELDLSWNFIRR 212 6899******9964 PP == domain 6 score: 7.2 bits; conditional E-value: 0.0047 LRR_1 1 nLeeLdLsnNnlsg 14 +Le+L+Ls N l + FUN_001295-T1 227 SLEKLNLSWNGLDD 240 79*********954 PP == domain 7 score: 8.5 bits; conditional E-value: 0.0017 LRR_1 2 LeeLdLsnNnlsgll 16 ++eLd+snN++s++ FUN_001295-T1 256 IKELDISNNRISDKG 270 689********8655 PP == domain 8 score: 5.7 bits; conditional E-value: 0.015 LRR_1 1 nLeeLdLsnNnlsgl 15 +Le+L++s+N + g+ FUN_001295-T1 283 KLEVLNVSHNLIFGS 297 69********99654 PP >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 6.6 1.5e+04 43 54 .. 253 264 .. 241 267 .. 0.69 2 ! 23.9 0.1 2.4e-08 5.5e-05 28 66 .. 407 442 .. 375 443 .. 0.78 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 6.6 EF-hand_7 43 eelfkefDldkd 54 ++++ke+D +++ FUN_001295-T1 253 NSTIKELDISNN 264 568889998886 PP == domain 2 score: 23.9 bits; conditional E-value: 2.4e-08 EF-hand_7 28 lrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 + ++ + ++d ++ +l++ +D+d+dG i+++EF++++ FUN_001295-T1 407 M---RRLKVMEDPHLVKLVEILDTDGDGEIDYSEFVKMF 442 3...5667789999***********************97 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.3 2.1e-08 5e-05 4 26 .. 420 442 .. 417 444 .. 0.88 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 2.1e-08 EF-hand_1 4 eiFrefDkDgdGkIdfeEfkell 26 ++ +++D+DgdG Id++Ef++++ FUN_001295-T1 420 KLVEILDTDGDGEIDYSEFVKMF 442 566899***************97 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.2 3.8e-07 0.00089 7 24 .. 424 441 .. 419 443 .. 0.90 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 3.8e-07 EF-hand_5 7 aiDlNgDGkIskeELkrl 24 +D++gDG+I+ +E+ ++ FUN_001295-T1 424 ILDTDGDGEIDYSEFVKM 441 68*************885 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 2.8 0.00021 0.49 5 36 .. 90 126 .. 89 133 .. 0.74 2 ! 15.2 0.8 1.2e-05 0.028 3 38 .. 116 156 .. 114 164 .. 0.84 3 ? 4.2 0.2 0.033 77 3 35 .. 144 182 .. 142 188 .. 0.78 4 ? 1.2 3.4 0.31 7.1e+02 3 30 .. 200 233 .. 170 242 .. 0.64 5 ! 10.0 3.4 0.0005 1.1 2 38 .. 227 268 .. 226 273 .. 0.81 6 ! 16.0 0.6 6.5e-06 0.015 3 40 .. 256 299 .. 254 303 .. 0.78 7 ? -1.7 0.0 2.5 5.8e+03 7 20 .. 373 386 .. 372 388 .. 0.72 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00021 LRR_4 5 tLdLsnNritdidp......lskLpnLetLdLsgNnki 36 +L++++N ++ ++ l++ L++L+L++N +i FUN_001295-T1 90 KLNIAHNELSIESGkcigrlLKSNRALTELNLANN-NI 126 6999999*996666886554445888******555.55 PP == domain 2 score: 15.2 bits; conditional E-value: 1.2e-05 LRR_4 3 LetLdLsnNritdidpls..k.Lpn...LetLdLsgNnkitd 38 L++L+L+nN+i + + ++ + Lp+ ++LdL++N + d FUN_001295-T1 116 LTELNLANNNIRKEGIIAiaQaLPHndtIRKLDLARN-GLGD 156 9************999555555999999******777.6655 PP == domain 3 score: 4.2 bits; conditional E-value: 0.033 LRR_4 3 LetLdLsnNritdidp..ls....kLpnLetLdLsgNnk 35 ++LdL+ N + d d l+ k +L +++Ls Nn FUN_001295-T1 144 IRKLDLARNGLGDSDArlLAegieKNDSLFIVNLSYNNF 182 689****99***999987335555899999999988865 PP == domain 4 score: 1.2 bits; conditional E-value: 0.31 LRR_4 3 LetLdLs.nNritdidp......lskLpnLetLdL 30 L +LdLs n i + ++ l+ +Le+L+L FUN_001295-T1 200 LLELDLSwN-FIRRAGEeaiaksLRYNSSLEKLNL 233 556666633.6666555453333224666777777 PP == domain 5 score: 10.0 bits; conditional E-value: 0.0005 LRR_4 2 nLetLdLs.nNritdidp..ls.kLpn...LetLdLsgNnkitd 38 +Le+L+Ls n + d + l+ +L++ ++Ld+ +Nn+i+d FUN_001295-T1 227 SLEKLNLSwN-GLDDCGTkeLGeSLKRnstIKELDI-SNNRISD 268 89******65.9999999775565777777******.7779987 PP == domain 6 score: 16.0 bits; conditional E-value: 6.5e-06 LRR_4 3 LetLdLsnNritdidpls......kLpnLetLdLsgNnki.tdls 40 ++Ld+snNri+d ++++ + +Le+L++s+N +i +++ FUN_001295-T1 256 IKELDISNNRISDKGLINiavgieGSDKLEVLNVSHN-LIfGSFE 299 699*********9666556677769*********888.6546555 PP == domain 7 score: -1.7 bits; conditional E-value: 2.5 LRR_4 7 dLsnNritdidpls 20 +L+ N+i d+++ FUN_001295-T1 373 YLNKNKIHASDLFK 386 78999998766655 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 1.1e-06 0.0026 5 26 .. 421 442 .. 417 445 .. 0.87 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 1.1e-06 EF-hand_6 5 aFklfDkdgdGyisleElraal 26 + +++D+dgdG i+++E+ +++ FUN_001295-T1 421 LVEILDTDGDGEIDYSEFVKMF 442 66799**************997 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.6 3.6 0.0082 19 25 61 .] 86 126 .. 76 126 .. 0.74 2 ! 6.5 2.1 0.0043 9.9 22 39 .. 111 128 .. 107 154 .. 0.63 3 ? 4.9 3.7 0.013 31 4 59 .. 145 208 .. 142 210 .. 0.66 4 ! 8.3 5.2 0.0011 2.7 5 61 .] 174 238 .. 170 238 .. 0.75 5 ! 9.5 1.2 0.00048 1.1 20 61 .] 249 294 .. 246 294 .. 0.77 6 ? -3.7 0.0 6.5 1.5e+04 15 29 .. 397 412 .. 396 413 .. 0.69 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.0082 LRR_8 25 snLkvLdLsnNllttlspgafsgL....psLrsLdLsgNrL 61 + L++ +N+l++ s +++ L ++L++L+L +N++ FUN_001295-T1 86 KTTSKLNIAHNELSIESGKCIGRLlksnRALTELNLANNNI 126 55567899999888888777665544448899999999987 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0043 LRR_8 22 kglsnLkvLdLsnNlltt 39 k++++L++L+L nN+++ FUN_001295-T1 111 KSNRALTELNLANNNIRK 128 677889999999999974 PP == domain 3 score: 4.9 bits; conditional E-value: 0.013 LRR_8 4 rsLdLssNrltslddga....FkglsnLkvLdLsnNllttlspgafsg....LpsLrsLdLsgN 59 r+LdL +N l + d +++ +L +Ls+N+ + s +f + +sL +LdLs N FUN_001295-T1 145 RKLDLARNGLGDSDARLlaegIEKNDSLFIVNLSYNNFSEASGVSFGDaltyNNSLLELDLSWN 208 6666666666654443311114568899999******999998777653333688888888888 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0011 LRR_8 5 sLdLssNrltslddgaFkg....lsnLkvLdLsnNllttlspga....fsgLpsLrsLdLsgNrL 61 +++Ls+N++++ + +F + +++L +LdLs N +++ ++a ++ +sL++L+Ls N L FUN_001295-T1 174 IVNLSYNNFSEASGVSFGDaltyNNSLLELDLSWNFIRRAGEEAiaksLRYNSSLEKLNLSWNGL 238 6788899998888877765422268************9987766111156689**********76 PP == domain 5 score: 9.5 bits; conditional E-value: 0.00048 LRR_8 20 aFkglsnLkvLdLsnNlltt...ls.pgafsgLpsLrsLdLsgNrL 61 + k++s k+Ld+snN+++ ++ + + g +L+ L++s+N + FUN_001295-T1 249 SLKRNSTIKELDISNNRISDkglINiAVGIEGSDKLEVLNVSHNLI 294 6788899999999999999733311257889999999999999986 PP == domain 6 score: -3.7 bits; conditional E-value: 6.5 LRR_8 15 slddgaFkg.lsnLkv 29 sl+ ++F + ++ Lkv FUN_001295-T1 397 SLSREVFMNgMRRLKV 412 5677777776888876 PP >> DUF2202 Uncharacterized protein domain (DUF2202) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.019 43 41 102 .. 140 206 .. 131 223 .. 0.77 2 ! 9.5 0.1 0.00048 1.1 75 142 .. 235 312 .. 218 316 .. 0.76 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.019 DUF2202 41 hmdavksl.lerygledPaled.vrGafknqdlrel...ynklvekgsdslvdalkvgatveeldis 102 h d++++l l r gl d +++ + G kn l + yn++ e + +s++dal + eld+s FUN_001295-T1 140 HNDTIRKLdLARNGLGDSDARLlAEGIEKNDSLFIVnlsYNNFSEASGVSFGDALTYNNSLLELDLS 206 889998887899999999887624677788776433335******************9999999987 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00048 DUF2202 75 ynklvekgsdslvdalkvgatveeldisd........lera..leetsnkditavysnlekGsrnhlrsfvrdvedrG 142 +n l + g ++l+++lk +t+ eldis+ ++ a +e +++ ++ +v +nl Gs++ ++ ++ ++G FUN_001295-T1 235 WNGLDDCGTKELGESLKRNSTIKELDISNnrisdkglINIAvgIEGSDKLEVLNVSHNLIFGSFEGVKKVLEGLHKNG 312 677778899*****************9862322233212222256688889999999999999999998888888887 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 4.3 1e+04 8 24 .. 248 263 .. 248 267 .. 0.67 2 ? 14.4 0.4 1.4e-05 0.032 5 53 .. 398 444 .. 395 445 .. 0.78 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 4.3 EF-hand_8 8 esLkrilalLglqdlse 24 esLkr++++ + d+s+ FUN_001295-T1 248 ESLKRNSTI-KELDISN 263 799999865.5555555 PP == domain 2 score: 14.4 bits; conditional E-value: 1.4e-05 EF-hand_8 5 ItresLkrilalLglqd...lsedevdtlfrefDtDgdGkisfeeFcvller 53 ++re ++ g+++ +++ + l+ ++DtDgdG i+ eF+ ++++ FUN_001295-T1 398 LSREVFMN-----GMRRlkvMEDPHLVKLVEILDTDGDGEIDYSEFVKMFFQ 444 56666666.....666666577777888999*****************9986 PP >> LRR_R13L1-DRL21 R13L1/DRL21 LRRs # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.4 0.7 1.6e+03 11 74 .. 88 147 .. 83 153 .. 0.65 2 ? 10.3 0.2 0.0003 0.7 25 78 .. 214 263 .. 208 269 .. 0.87 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.7 LRR_R13L1-DRL21 11 rgeLeIsnlenvkskeeakeanLkeKknLksLeLewssdeeesksekeeevleaLqPhsnLkeL 74 + +L+I + e ++ + Lk+ + L++L+L ++ + +e ++ +aL ++++++L FUN_001295-T1 88 TSKLNIAHNELSIESGKCIGRLLKSNRALTELNLANNNIR----KEGIIAIAQALPHNDTIRKL 147 5577777777777777777778888888888888765543....55555556666666666666 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0003 LRR_R13L1-DRL21 25 keeakeanLkeKknLksLeLewssdeeesksekeeevleaLqPhsnLkeLkikg 78 eea L+ ++L++L+L+w+ + + ++e+ e+L+ +s++keL i++ FUN_001295-T1 214 GEEAIAKSLRYNSSLEKLNLSWNGLD----DCGTKELGESLKRNSTIKELDISN 263 47899999**************9987....567788999************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (446 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 501 (0.0196124); expected 510.9 (0.02) Passed bias filter: 426 (0.0166765); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4409.93 // Query: FUN_001296-T1 [L=696] Description: FUN_001296 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (696 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 635 (0.0248581); expected 510.9 (0.02) Passed bias filter: 414 (0.0162067); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6714.62 // Query: FUN_001297-T1 [L=103] Description: FUN_001297 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3330 (0.130358); expected 510.9 (0.02) Passed bias filter: 941 (0.036837); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 1018.25 // Query: FUN_001298-T1 [L=604] Description: FUN_001298 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (604 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1991 (0.0779409); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 181 (0.00708554); expected 25.5 (0.001) Passed Fwd filter: 31 (0.00121354); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.45u 0.42s 00:00:00.87 Elapsed: 00:00:00.42 # Mc/sec: 5839.79 // Query: FUN_001299-T1 [L=3358] Description: FUN_001299 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.071 13.0 208.7 0.009 16.0 6.7 13.7 11 Chorion_3 Chorion family 3 Domain annotation for each model (and alignments): >> Chorion_3 Chorion family 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.0 6.7 3.5e-07 0.009 154 209 .. 131 182 .. 62 219 .. 0.80 2 ? 4.6 10.4 0.001 26 141 210 .. 341 404 .. 329 435 .. 0.67 3 ? -2.8 18.1 0.18 4.6e+03 146 208 .. 477 534 .. 467 588 .. 0.68 4 ? 3.3 14.4 0.0026 66 144 194 .. 611 662 .. 592 739 .. 0.62 5 ? 4.0 11.7 0.0015 39 144 210 .. 788 827 .. 762 867 .. 0.50 6 ? 11.9 6.4 6.3e-06 0.16 144 208 .. 961 1012 .. 933 1061 .. 0.53 7 ? 10.0 8.2 2.4e-05 0.62 143 193 .. 1135 1185 .. 1093 1218 .. 0.63 8 ? 1.3 15.0 0.011 2.8e+02 145 206 .. 1308 1356 .. 1280 1366 .. 0.47 9 ? 9.3 10.7 3.8e-05 0.98 151 235 .. 1494 1570 .. 1468 1587 .. 0.65 10 ? 7.6 10.4 0.00013 3.2 142 234 .. 1691 1776 .. 1676 1813 .. 0.63 11 ? 4.8 16.7 0.00089 23 144 215 .. 1861 1925 .. 1856 1946 .. 0.69 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 3.5e-07 Chorion_3 154 ppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqkevinkvPtPlslnPvy 209 p iiv++P +v +P++v + + v+ + P + +q v+ + PtP+ +Pvy FUN_001299-T1 131 PDIIVHRP----DVVIHQPSIVYHQSSVVVHRAPVIYHQPPVVFHQPTPMVSQPVY 182 35666666....55556666666666666666665555556777889999999999 PP == domain 2 score: 4.6 bits; conditional E-value: 0.001 Chorion_3 141 gqnnhqviatqPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqkevinkvPtPlslnPvyv 210 g+ +h +++++P p+i Pp +v +P +v++ iy+ + v+ q i ++P + +P v FUN_001299-T1 341 GHRKHSIVINRP--PMIYY----PPPKVYHQPDIVMHQPALIYHRPTLVLQQPTTIVHHPDLVYHQPSVV 404 889999999998..55443....33456667777777767777765555555667777777666666433 PP == domain 3 score: -2.8 bits; conditional E-value: 0.18 Chorion_3 146 qviatqPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqke.vinkvPtPlslnPv 208 v ++qP +i+ + P ++ ++Pp+vv+ +P++ + +P i++ v+ P ++ Pv FUN_001299-T1 477 VVAIHQP--AIVYHSP----PEIIQKPPIVVQQSPMVVHRQPILIHRPPlVVPSSPLIIRRPPV 534 4556777..7777777....35667788888888888888888877753144444544444444 PP == domain 4 score: 3.3 bits; conditional E-value: 0.0026 Chorion_3 144 nhqviatqPlppiivkqPal...PpkqvvsgPplvvkaaPviykikPsviyqke 194 + +vi+++P i++++P++ p++vv Pp++ + v+++ +P +++q FUN_001299-T1 611 RPDVIVHRP--DIVIHRPSIvyhQPSVVVHRPPIIYRQPAVVFHQPPPMVHQPI 662 567899998..8889999542223555666666666666666666666665543 PP == domain 5 score: 4.0 bits; conditional E-value: 0.0015 Chorion_3 144 nhqviatqPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqkevinkvPtPlslnPvyv 210 + ++i+++P i+v++P++ v +P++vv+ P++y P v FUN_001299-T1 788 RPDIIVHRP--DIVVHRPSI----VYHQPSVVVHRPPIVY---------------------QSPALV 827 223444444..444444422....2222222222222222.....................222222 PP == domain 6 score: 11.9 bits; conditional E-value: 6.3e-06 Chorion_3 144 nhqviatqPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqk.evinkvPtPlslnPv 208 + +iv++P vv + p+vv P ++ +P viy++ v+ + P P+ +P+ FUN_001299-T1 961 KP---------DVIVHRP-----DVVIHRPAVVFHQPSVLIHRPPVIYHQpPVVFHQPAPMVSQPI 1012 22.........3333333.....2333333333333433333444444431344555555555554 PP == domain 7 score: 10.0 bits; conditional E-value: 2.4e-05 Chorion_3 143 nnhqviatqPlppiivkqPal...PpkqvvsgPplvvkaaPviykikPsviyqk 193 + +vi+++P +++++P++ p++vv Pp++ + P+i++ +P ++ q+ FUN_001299-T1 1135 HKPDVIVHRP--DLVIHRPSVvlhQPSVVVHRPPVIYRQPPIIFHQPPPMV-QQ 1185 3445666666..566666643222234444555555555555555544443.23 PP == domain 8 score: 1.3 bits; conditional E-value: 0.011 Chorion_3 145 hqviatqPlppiivkqPal...PpkqvvsgPplvvkaaPviykikPsviyqkevinkvPtPlsln 206 +v+ ++P i++++P++ p++vv P+++ + Pv+++ +P + + FUN_001299-T1 1308 PDVVLHRP--DIVIHRPSVifhQPSVVVHRPSVIYRQPPVVFHQPPPTV--------------HQ 1356 33444444..444444432111223444444444444444444444444..............33 PP == domain 9 score: 9.3 bits; conditional E-value: 3.8e-05 Chorion_3 151 qPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqk.evinkvPtPlslnPvyv..kvykPgkkieaplvpevqqqysapa 235 + p iiv++P vv + + vv P + +P viy+ v+ + PtP+ +P+y ++yk +vp + +a + FUN_001299-T1 1494 R--PNIIVHRP-----DVVIHQASVVYHQPSVVVHRPPVIYNPpPVVFHQPTPMVNQPMYTshDIYKGQL----QFVPYASNIKHAQS 1570 3..37788888.....4555555555555555555566666542477789****999*997334777554....44544444444444 PP == domain 10 score: 7.6 bits; conditional E-value: 0.00013 Chorion_3 142 qnnhqviatqPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqkevinkvPtPlslnPvyvkvykPgkkieaplvpevqqqysap 234 ++ v++ +P p++ + P p +v +P ++v+ v+++ +Psv+y++ + + P+ n v +P+ i++p++ + p FUN_001299-T1 1691 SKKNAVVIRRP--PLVYH-P---PPEVYHKPDVIVHRPDVVIH-QPSVVYHQPSVMVHRPPVIYNQPPVIFHQPSPMINQPIIHSRDHYIARP 1776 55556666666..44333.3...23455555555555444444.4666666666665555666665556666666666666666655555555 PP == domain 11 score: 4.8 bits; conditional E-value: 0.00089 Chorion_3 144 nhqviatqPlppiivkqPalPpkqvvsgPplvvkaaPviykikPsviyqkevinkvPtPlslnPvyvkvykP 215 ++++++ +P pii + P ++ P +vv+ aP++++ +P + +q v+ + P + +P v +P FUN_001299-T1 1861 KNDIVVSRP--PIIYHPP----PEIYHRPDIVVHRAPIVLHRPPIIYHQPPVVVHRPAVVYHQPPVVF-HQP 1925 678888888..8888765....5677888888888888888777666666777777777777765443.333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (3358 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2288 (0.0895674); expected 510.9 (0.02) Passed bias filter: 493 (0.0192993); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 31 (0.00121354); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.99u 0.43s 00:00:01.42 Elapsed: 00:00:00.46 # Mc/sec: 29387.18 // Query: FUN_001300-T1 [L=1352] Description: FUN_001300 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1352 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1362 (0.0533177); expected 510.9 (0.02) Passed bias filter: 651 (0.0254844); expected 510.9 (0.02) Passed Vit filter: 134 (0.00524564); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.66u 0.41s 00:00:01.07 Elapsed: 00:00:00.43 # Mc/sec: 12572.47 // Query: FUN_001301-T1 [L=377] Description: FUN_001301 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.083 13.2 1.4 0.097 13.0 0.1 1.7 2 TMEM208_SND2 SRP-independent targeting protein 2/TMEM208 Domain annotation for each model (and alignments): >> TMEM208_SND2 SRP-independent targeting protein 2/TMEM208 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 3.8e-06 0.097 114 165 .. 15 68 .. 3 76 .. 0.65 2 ? -2.4 0.3 0.21 5.3e+03 149 159 .. 84 94 .. 68 110 .. 0.52 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 3.8e-06 TMEM208_SND2 114 kfWllylvvPayalYklwglilgpkff.kgqga...aeeaeeeeakskrqeKlekr 165 + + +vP+ + Ykl + + + ++ + +++ a+e+e+ee+ +k +eK+e + FUN_001301-T1 15 VILYQTSAVPVASSYKLENENI-MDVMeA-KEKseeASEEEKEEESDKEEEKQEDK 68 45666889*********98666.467733.33335655666666666777777665 PP == domain 2 score: -2.4 bits; conditional E-value: 0.21 TMEM208_SND2 149 aeeeeakskrq 159 +e++ ++k+ FUN_001301-T1 84 EESKDDEEKKD 94 33333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (377 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3519 (0.137757); expected 510.9 (0.02) Passed bias filter: 985 (0.0385594); expected 510.9 (0.02) Passed Vit filter: 509 (0.0199256); expected 25.5 (0.001) Passed Fwd filter: 200 (0.00782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.91u 0.47s 00:00:01.38 Elapsed: 00:00:00.46 # Mc/sec: 3329.92 // Query: FUN_001301-T2 [L=343] Description: FUN_001301 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.082 13.2 0.1 0.082 13.2 0.1 1.8 2 TMEM208_SND2 SRP-independent targeting protein 2/TMEM208 Domain annotation for each model (and alignments): >> TMEM208_SND2 SRP-independent targeting protein 2/TMEM208 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.1 3.2e-06 0.082 114 165 .. 15 68 .. 3 78 .. 0.65 2 ? -2.2 0.5 0.18 4.5e+03 151 158 .. 86 93 .. 67 115 .. 0.55 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 3.2e-06 TMEM208_SND2 114 kfWllylvvPayalYklwglilgpkff.kgqga...aeeaeeeeakskrqeKlekr 165 + + +vP+ + Ykl + + + ++ + +++ a+e+e+ee+ +k +eK+e + FUN_001301-T2 15 VILYQTSAVPVASSYKLENENI-MDVMeA-KEKseeASEEEKEEESDKEEEKQEDK 68 45666899*********98666.467733.33335655555566666666666655 PP == domain 2 score: -2.2 bits; conditional E-value: 0.18 TMEM208_SND2 151 eeeakskr 158 ++ ++k+ FUN_001301-T2 86 SKDDEEKK 93 22233333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (343 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3325 (0.130162); expected 510.9 (0.02) Passed bias filter: 916 (0.0358583); expected 510.9 (0.02) Passed Vit filter: 489 (0.0191427); expected 25.5 (0.001) Passed Fwd filter: 207 (0.00810335); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.92u 0.44s 00:00:01.36 Elapsed: 00:00:00.45 # Mc/sec: 3041.84 // Query: FUN_001303-T1 [L=284] Description: FUN_001303 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (284 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2181 (0.0853787); expected 510.9 (0.02) Passed bias filter: 445 (0.0174202); expected 510.9 (0.02) Passed Vit filter: 163 (0.0063809); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.35u 0.34s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2783.92 // Query: FUN_001304-T1 [L=302] Description: FUN_001304 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (302 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2486 (0.0973185); expected 510.9 (0.02) Passed bias filter: 610 (0.0238794); expected 510.9 (0.02) Passed Vit filter: 204 (0.00798591); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 2961.58 // Query: FUN_001305-T1 [L=82] Description: FUN_001305 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.21 12.6 2.4 0.27 12.2 2.4 1.1 1 CENP-B_dimeris Centromere protein B dimerisation domain 3.5 5.7 7.9 3.7 5.6 7.9 1.0 1 Vir1p Virilizer, yeast Domain annotation for each model (and alignments): >> CENP-B_dimeris Centromere protein B dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 2.4 2.1e-05 0.27 7 50 .. 14 58 .. 11 63 .. 0.79 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 2.1e-05 CENP-B_dimeris 7 eggedsdsds.deeeddeeedeededeeddedgdevpvpsfgeam 50 g +ds+ ds d + + + + ++ +d +dde gd++ +g+++ FUN_001305-T1 14 SGNNDSNKDSiDSNGNSNGNTDNSNDSDDDERGDNMAWGNMGNTL 58 588999999944455566677888999********9998888765 PP >> Vir1p Virilizer, yeast # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 7.9 0.00029 3.7 359 395 .. 11 47 .. 4 70 .. 0.68 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.00029 Vir1p 359 kkcittnninnnninnnnvinnstnttsttnninnns 395 c +n+ n++ i+ n+++n++t++++++++ + FUN_001305-T1 11 ISCSGNNDSNKDSIDSNGNSNGNTDNSNDSDDDERGD 47 4688889999999999999999998887774433322 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (82 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 743 (0.0290859); expected 510.9 (0.02) Passed bias filter: 379 (0.0148366); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.23u 0.41s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 833.48 // Query: FUN_001306-T1 [L=563] Description: FUN_001306 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (563 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1561 (0.0611078); expected 510.9 (0.02) Passed bias filter: 435 (0.0170288); expected 510.9 (0.02) Passed Vit filter: 94 (0.00367978); expected 25.5 (0.001) Passed Fwd filter: 42 (0.00164416); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.70u 0.37s 00:00:01.06 Elapsed: 00:00:00.44 # Mc/sec: 5151.96 // Query: FUN_001307-T1 [L=309] Description: FUN_001307 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1190 (0.0465845); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3084.44 // Query: FUN_001308-T1 [L=337] Description: FUN_001308 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.019 13.4 0.7 0.025 13.0 0.7 1.1 1 V_ATPase_I V-type ATPase 116kDa subunit family 0.14 11.4 2.3 0.19 10.9 2.3 1.2 1 Presenilin Presenilin 0.14 10.8 19.0 0.18 10.5 19.0 1.1 1 Nop14 Nop14-like family 0.17 11.9 4.2 0.24 11.4 4.2 1.2 1 PFF1_TM Vacuolar membrane protease, transmembrane doma 0.34 10.4 0.8 0.49 9.8 0.8 1.3 1 O-antigen_lig O-antigen ligase like membrane protein 3.1 7.6 4.9 4.2 7.1 4.9 1.1 1 DUF7502 Family of unknown function (DUF7502) 5.3 6.7 21.9 8.4 6.1 21.9 1.2 1 BUD22 BUD22 Domain annotation for each model (and alignments): >> V_ATPase_I V-type ATPase 116kDa subunit family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.7 6.8e-06 0.025 616 686 .. 2 80 .. 1 116 [. 0.55 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 6.8e-06 V_ATPase_I 616 qvvLllialvcvpvllllkplilklkhkkkkkkkekkeeee.............................eeeeeeeeeeeeeeeeeeeeeeeeee 682 + vLl++++v++ v + +kp++ + + k+kek++ e + ee + FUN_001308-T1 2 KLVLLFVVFVSILVVIRAKPFTEEADDDVMLKQKEKSDVGEelensddekedeedgssidqeprarekrdA--------------------LEE-A 76 5799******************9998887776666655544455555554444333333322222111110....................111.1 PP V_ATPase_I 683 eeee 686 e+ e FUN_001308-T1 77 ENFE 80 1111 PP >> Presenilin Presenilin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 2.3 5.2e-05 0.19 238 309 .. 33 104 .. 4 131 .. 0.35 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 5.2e-05 Presenilin 238 eeeeaekkkeeeeeeskkeeseeeeseksassse.eeeseeteeeesaeeeseeeseeesseaessteessee 309 +++e++++ ee e++++++e+ee + +++ ++ + +e++++ ee+e+ e+ ++++ +e+++e++++te+s+++ FUN_001308-T1 33 KQKEKSDVGEELENSDDEKEDEE-DGSSIDQEPRaREKRDALEEAENFEKAKDSSGNESEEEKDDNTEKSNKD 104 22222222222222222222111.1122222211111222221111111111111111111111111111111 PP >> Nop14 Nop14-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 19.0 4.9e-05 0.18 313 404 .. 25 112 .. 18 157 .. 0.63 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 4.9e-05 Nop14 313 dleddfvveeeeeeeefglgkglketateeeeededdfeidddlveseseleeeeeeedeeeeeeeeeeeeeeededdlsdleseeeeedel 404 + +dd +++++e+++ +g++l+ ++++e+e++ed +id++ ++e+ + +ee e+ e+ ++++ +e+eee+d++++++++++ ++de FUN_001308-T1 25 EADDDVMLKQKEKSD---VGEELE-NSDDEKEDEEDGSSIDQEPRAREKRDALEEAENFEKAKDSSGNESEEEKDDNTEKSNKDSGRDDDEG 112 456677777655555...678884.4657788888888888877777777776555555555555555444444444444444344444443 PP >> PFF1_TM Vacuolar membrane protease, transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 4.2 6.5e-05 0.24 126 213 .. 20 107 .. 1 121 [. 0.33 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 6.5e-05 PFF1_TM 126 kklarekkdsss.nyssesqieeeeegeealeqpedqeeaeeddeesveddnestteanptentnegeqsdseeeeederapllegsss 213 k +++e++d+ +++ +s ee e+ + e++++++ ++ d+e+ +++++ +ea++ e+++++++ +seee++d+ ++s + FUN_001308-T1 20 KPFTEEADDDVMlKQKEKSDVGEELENSDD-EKEDEEDGSSIDQEPRAREKRDALEEAENFEKAKDSSGNESEEEKDDNTEKSNKDSGR 107 233333332222111111111111111111.1222222333333333344444445555554444444444444444433222222222 PP >> O-antigen_lig O-antigen ligase like membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.8 0.00014 0.49 254 299 .. 4 85 .. 1 111 [. 0.68 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00014 O-antigen_lig 254 vvllvllggllvvtpvsPavknvkieiqlieekkseqeekkkkee....................................r 299 v+l v+++ +lvv P+ ++ ++ l +++ks e+ +++ + FUN_001308-T1 4 VLLFVVFVSILVVIRAKPFTEEADDDVMLKQKEKSDVGEELENSDdekedeedgssidqeprarekrdaleeaenfekakdS 85 78899**************************999976665555544455566776666666666665555555554444333 PP >> DUF7502 Family of unknown function (DUF7502) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 4.9 0.0012 4.2 156 249 .. 11 109 .. 2 118 .. 0.47 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0012 DUF7502 156 tvvvvvvvslasvqvavvdlslaelggdeedtgseddeededeglqdgsevLGdp...edveaGdeelnaevegsgggggede...teapaaydsg 245 + ++vv+ + ++ a d+ l++ ++ + ++ ++++de+e +dgs++ +p e +a++e++n e + ++g++++e ++++++ +++ FUN_001308-T1 11 VSILVVIRAKPFTEEADDDVMLKQKEKS-DVGEELENSDDEKEDEEDGSSIDQEPrarEKRDALEEAENFEKAKDSSGNESEEekdDNTEKSNKDS 105 3444444555555556666666444433.3333333444455556777777766533345556666666555544444444332122333333334 PP DUF7502 246 gfss 249 g ++ FUN_001308-T1 106 GRDD 109 4333 PP >> BUD22 BUD22 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 21.9 0.0023 8.4 168 263 .. 29 138 .. 18 153 .. 0.46 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0023 BUD22 168 e.....eeesdkedessdsedekeeseddeeeeeeeedeedaeddeeeeeedlsqydgllasddedednynevtdeesseesdesdsses...... 252 + +e+sd +e ++s+d e++++++ ++ ++e +++++d+ ee e++++ ++ ++++e+ ++++++e+s+++s ++d++ + FUN_001308-T1 29 DvmlkqKEKSDVGEELENSDD--EKEDEEDGSSIDQEPRAREKRDALEEAENFEKAKDSSGNESEE---EKDDNTEKSNKDSGRDDDEGElqwknt 119 122333455666777777777..2222333333333333333333344445555554433333333...334555555555555555555556666 PP BUD22 253 ........dsesesessek 263 +s+ + +++e FUN_001308-T1 120 lgirgplsISAIQLPDPEV 138 6666666655555555444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (337 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1959 (0.0766882); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 156 (0.00610687); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.41u 0.42s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 3256.79 // Query: FUN_001309-T1 [L=928] Description: FUN_001309 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (928 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 667 (0.0261108); expected 510.9 (0.02) Passed bias filter: 380 (0.0148757); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.41u 0.38s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 8880.66 // Query: FUN_001310-T1 [L=279] Description: FUN_001310 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-54 185.5 6.8 1.7e-54 185.3 6.8 1.0 1 Tetraspanin Tetraspanin family 0.00078 20.0 0.4 0.00078 20.0 0.4 2.6 3 Phage_holin_3_6 Putative Actinobacterial Holin-X, holin supe ------ inclusion threshold ------ 0.028 13.8 0.4 0.043 13.2 0.4 1.2 1 DUF6057 Family of unknown function (DUF6057) 0.23 12.0 2.2 0.53 10.8 2.2 1.7 1 Jagunal Jagunal, ER re-organisation during oogenesis 0.34 11.5 8.8 0.093 13.3 4.5 1.9 2 DUF350 Domain of Unknown Function (DUF350) 1.3 9.0 3.4 1.9 8.4 3.0 1.4 1 DUF2981 Protein of unknown function (DUF2981) Domain annotation for each model (and alignments): >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 185.3 6.8 4e-58 1.7e-54 1 223 [. 11 247 .. 11 249 .. 0.92 Alignments for each domain: == domain 1 score: 185.3 bits; conditional E-value: 4e-58 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 1 lkyllfllnllflllGllllavGvwlksleaassalsesseaaalipvllivlGaviflvgflGccgalkesrcllllyfvlllllflaelaagil 96 lky+lf++nll + +G ++++vG+w++++++++++ s+ s+++a++ ++++G++if+++f+G +gal+e+ c+l +y++++++++++e++ag+l FUN_001310-T1 11 LKYTLFVFNLLYWCIGGVMIGVGLWAVTQKSDYNTFSSISTDPAAV---MVAVGGFIFIISFFGTVGALRENICFLKTYMIVMIIIVILEVIAGLL 103 79************************99999999999999999999...*********************************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxx.......... RF Tetraspanin 97 afvyrdkekeelsnwlkksledsyedasdlkskkeealdslqeelkCCGvnsysDw..........eksendgvPesCcknsesat.......... 172 af++ + ++++++++k+++ ++y+d+ dl ++a+d +qe+++CCG ++ +Dw + e++gvP sCc ++ ++ FUN_001310-T1 104 AFAFWPEVQKSVDSKFKTAI-ERYRDDVDL----QNAIDAVQENFQCCGSTDLNDWdinryfkcggRSPEQCGVPYSCCVRKLDERpnvqcgwhar 194 *******7777777777777.556666666....6*********************************************9998889****99988 PP ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 173 ...alsndssilykegCkekleeflrknlkiigavvialgviqllgiilacclc 223 +l + +i+ +gC+++++e++r++l i++av++a+++ +++gii++ +++ FUN_001310-T1 195 eqhRLALKGKIY-ITGCLDAVLEWFRNHLVIVAAVAVAFAFPEVVGIIMTHLFI 247 877777777777.*******************999999999*******987766 PP >> Phage_holin_3_6 Putative Actinobacterial Holin-X, holin superfamily III # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 0.33 1.4e+03 77 112 .. 20 53 .. 10 56 .. 0.62 2 ! 20.0 0.4 1.8e-07 0.00078 37 113 .. 55 131 .. 50 133 .. 0.84 3 ? 0.6 0.3 0.18 7.8e+02 67 90 .. 223 246 .. 205 256 .. 0.54 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.33 Phage_holin_3_6 77 avllvvaavlalvgrkrlkkasplpertieelkedv 112 +++ +++v++ vg+ ++ ++s t ++++ d+ FUN_001310-T1 20 LLYWCIGGVMIGVGLWAVTQKSD--YNTFSSISTDP 53 67777777777777777777665..34555555555 PP == domain 2 score: 20.0 bits; conditional E-value: 1.8e-07 Phage_holin_3_6 37 agllaaagvlallgllfllval...alalaevlplwlaalivaavllvvaavlalvgrkrlkkasp.lpertieelkedve 113 a+++a++g++++++++ + al + +l + + ++i+ ++l v+a++la++ + +++k ++++ie ++dv+ FUN_001310-T1 55 AVMVAVGGFIFIISFFGTVGALrenICFL----KTYMIVMIIIVILEVIAGLLAFAFWPEVQKSVDsKFKTAIERYRDDVD 131 77888888888888888888886655556....4556788899********************9999************97 PP == domain 3 score: 0.6 bits; conditional E-value: 0.18 Phage_holin_3_6 67 plwlaalivaavllvvaavlalvg 90 +a+ + +a+ vv++++ + FUN_001310-T1 223 VIVAAVAVAFAFPEVVGIIMTHLF 246 222333333344444445544444 PP >> DUF6057 Family of unknown function (DUF6057) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.4 1e-05 0.043 149 264 .. 12 118 .. 3 162 .. 0.47 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1e-05 DUF6057 149 llalvllpllywlaGsvallfallvllyellkkkkrkksaslllllllllvalllvl..avllplltserlllyplirlayyrfplelptlllvvw 242 ++l+++ llyw +G+v++ + l+++ +k+ +++ s+ + +++va++ ++ +++++ ++ r + l + ++++v+ FUN_001310-T1 12 KYTLFVFNLLYWCIGGVMIGVGLWAVT----QKSDYNTFSSISTDPAAVMVAVGGFIfiISFFGTVGALRENICFL--------KTYMIVMIIIVI 95 57888999**********998877774....444444444444444444444442221133333333322221111........112233333333 PP DUF6057 243 lllllvlllaallkka.kslkkk 264 l +++ ll++a+ ++ ks++ k FUN_001310-T1 96 LEVIAGLLAFAFWPEVqKSVDSK 118 33333333333333332333222 PP >> Jagunal Jagunal, ER re-organisation during oogenesis # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 2.2 0.00012 0.53 89 136 .. 65 114 .. 2 128 .. 0.80 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00012 Jagunal 89 lllsllglsalkknkikllklyvigilvlgllpllygavey..lsevley 136 +++s++g+ + +i lk+y+i+++++ +l ++ g++ +ev++ FUN_001310-T1 65 FIISFFGTVGALRENICFLKTYMIVMIIIVILEVIAGLLAFafWPEVQKS 114 688999******************************98654114555555 PP >> DUF350 Domain of Unknown Function (DUF350) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 4.5 2.2e-05 0.093 10 98 .. 20 109 .. 12 127 .. 0.75 2 ? -0.2 0.1 0.32 1.3e+03 82 89 .. 227 234 .. 205 261 .. 0.45 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.2e-05 DUF350 10 lvyflvglvllvlgllvydlltpydereliregnvAaaislagallglalila.aaisgsaslldfllwgliglvllllafllvdklllp 98 l+y+++g v++ +gl++++ y+ + i + +A+ ++++g+++ +++ + +a+ ++ +l + + +i +v+l ++ l+ ++p FUN_001310-T1 20 LLYWCIGGVMIGVGLWAVTQKSDYNTFSSISTDPAAVMVAVGGFIFIISFFGTvGALRENICFLKTYMIVMIIIVILEVIAGLLAFAFWP 109 79******************************************9988876541555555556666666666666665555555533335 PP == domain 2 score: -0.2 bits; conditional E-value: 0.32 DUF350 82 lvllllaf 89 v++++af FUN_001310-T1 227 AVAVAFAF 234 11111111 PP >> DUF2981 Protein of unknown function (DUF2981) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 3.0 0.00044 1.9 41 76 .. 65 100 .. 28 110 .. 0.82 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.00044 DUF2981 41 vlsavlGflGalkrslvveavylvfylvslvlvvlt 76 + + +G++Gal+ ++++ +y+++ ++ + l v+ FUN_001310-T1 65 FIISFFGTVGALRENICFLKTYMIVMIIIVILEVIA 100 4566789****************9998877776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (279 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1392 (0.0544921); expected 510.9 (0.02) Passed bias filter: 665 (0.0260325); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2766.37 // Query: FUN_001311-T1 [L=282] Description: FUN_001311 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-24 87.4 2.9 2.3e-24 87.0 2.9 1.2 1 VWA von Willebrand factor type A domain 3.3e-15 57.1 0.4 1.2e-14 55.3 0.2 1.9 2 VWA_2 von Willebrand factor type A domain 0.00012 22.6 0.2 0.00033 21.2 0.2 1.7 1 VWA_3 von Willebrand factor type A domain 0.0023 17.9 0.3 0.0029 17.6 0.3 1.1 1 VWA_CoxE VWA domain containing CoxE-like protein ------ inclusion threshold ------ 0.065 13.3 0.0 2.2 8.3 0.0 2.3 2 BRCA-2_helical BRCA2, helical 0.15 12.7 0.1 0.33 11.6 0.1 1.6 1 DUF2201 VWA-like domain (DUF2201) Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.0 2.9 5.5e-28 2.3e-24 1 172 [. 80 247 .. 80 249 .. 0.86 Alignments for each domain: == domain 1 score: 87.0 bits; conditional E-value: 5.5e-28 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrtefslndysskeellsavkslkykgggttntgkalkyalenlfkss 96 D++++lD+S+s+++++f ++ +l++lv++l ++t+++ ++y+++++t+f++++ + ++ l a++ +ggg+tnt +alk +e + ++ FUN_001311-T1 80 DVIIVLDSSSSVSKGEFARALIALQDLVKKLR---NDTNYAAITYATRATTQFNFTNSFQTAKKLLALE----RGGGKTNTQDALKRCQEMFVGDQ 168 9*******************************...**********************443233333444....4778888**********999999 PP VWA 97 agaRegapkvvvlltdGksqdg..dveeaarelksagvkvfavgv..gnadeeeLekiasepdeghvftvedfealeelq 172 gaR+g + ++++tdG+s+ + + + a +lk g++vf+++v +e+ ++as+++ h+f+v ++++l e++ FUN_001311-T1 169 YGARQGSLRRILVVTDGQSNINrdQTVTRAFQLKLLGIEVFVIAVgqYLEGIQEMVQMASSTN-AHMFRVLNMKNLVEVV 247 9******************88656777778888999*********433355677999999999.9*******99887765 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.3 0.2 2.8e-18 1.2e-14 1 108 [] 81 186 .. 81 186 .. 0.94 2 ? -1.1 0.0 0.95 4e+03 29 63 .. 221 260 .. 212 275 .. 0.55 Alignments for each domain: == domain 1 score: 55.3 bits; conditional E-value: 2.8e-18 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallkslpgd.rvglvtfsdnpevlipltkdkakllealrrleatgggtdlaaAlqlarkalkkrr.. 93 +++vlD+S S+++g ++++a a+++l+k+l++d +++ +t+++++++ +++t + +++++ l +le gg+t++++Al+ +++++ ++ FUN_001311-T1 81 VIIVLDSSSSVSKG-----EFARALIALQDLVKKLRNDtNYAAITYATRATTQFNFTNSFQTAKK-LLALERGGGKTNTQDALKRCQEMFVGDQyg 170 79************.....8***************9666******************98888775.8899989*****************999999 PP VWA_2 94 .rknakriivlitDge 108 r++ r+i+++tDg+ FUN_001311-T1 171 aRQGSLRRILVVTDGQ 186 999***********96 PP == domain 2 score: -1.1 bits; conditional E-value: 0.95 VWA_2 29 eallk...slpgdrvglvtfsd..npevlipltkdkakll 63 +++++ s + + ++++ + ++ +lip + k+ l+ FUN_001311-T1 221 QEMVQmasSTNAHMFRVLNMKNlvEVVKLIPNRGQKSWLE 260 4444433244566777777777444444455555555555 PP >> VWA_3 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.2 7.7e-08 0.00033 2 147 .. 80 228 .. 79 232 .. 0.79 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 7.7e-08 VWA_3 2 evvilvDvsss.msgeieavkdalklalrqLptndkinilvfgtkarplfpgsrtvssreldeaaqfvktlqpplGgtnllqaLkealrqk..... 91 +v+i++D+sss ++ge + al+ ++ L + + + + t ++++ + + + a +++ +l+ G tn + aLk + + FUN_001311-T1 80 DVIIVLDSSSSvSKGEFARALIALQDLVKKLRNDTNYAAITYATR---ATTQFNFTN--SFQTA-KKLLALERGGGKTNTQDALKRCQEMFvgdqy 169 89********977787677788889999***99998776666665...445555555..44555.555666666999**********999999999 PP VWA_3 92 .ekrgyvrsvilltdgsp.aqtservsdeisqargkirvhalglgstlsa.amLqeLAe 147 +++g+ r ++++tdg++ + ++ v + + i v+++++g+ l + + + ++A FUN_001311-T1 170 gARQGSLRRILVVTDGQSnINRDQTVTRAFQLKLLGIEVFVIAVGQYLEGiQEMVQMAS 228 *999**************667788888888778899**********7777777777776 PP >> VWA_CoxE VWA domain containing CoxE-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.3 6.7e-07 0.0029 41 186 .. 63 212 .. 52 246 .. 0.69 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 6.7e-07 VWA_CoxE 41 gepvelvrrkpRkrkplrlvlllDvSgSmeaysavflallaAllrqfp.irtev.faFstrlvdlTdalderDpaeaLrrvsarved..vgGgTri 132 +++++l r+ + l+++++lD S S+++ f++ l Al++ ++ +r + a t +++T +++ +++++ +++ gG T+ FUN_001311-T1 63 HQTRRLYKRQVNLEDHLDVIIVLDSSSSVSK--GEFARALIALQDLVKkLRNDTnYAAITYATRATTQFN---FTNSFQTAKKLLALerGGGKTNT 153 55666666666777889*************9..7788888899999996665442566777777777777...66666666433333326777*** PP VWA_CoxE 133 gealaefrelvtrpaL...rrav..vlvvSDglegdareelleevaalrraarrlvwln 186 + al+ ++e + ++++ +lvv+Dg +r++ +++ +l+ ++ + +++ FUN_001311-T1 154 QDALKRCQEMFVGDQYgarQGSLrrILVVTDGQSNINRDQTVTRAFQLKLLGIEVFVIA 212 *********99766543245665669******998888888887777777666666665 PP >> BRCA-2_helical BRCA2, helical # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.00052 2.2 85 128 .. 58 104 .. 8 139 .. 0.84 2 ? 3.2 0.0 0.019 79 60 82 .. 215 237 .. 158 256 .. 0.85 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00052 BRCA-2_helical 85 edffgkell.legngiqLaD..ggllipddkgkvGkeefyralcdtp 128 ++f g+++ l ++ ++L D + ++++d++++v k ef ral++ FUN_001311-T1 58 QNFLGHQTRrLYKRQVNLEDhlDVIIVLDSSSSVSKGEFARALIALQ 104 666666654155688999998788999****************9865 PP == domain 2 score: 3.2 bits; conditional E-value: 0.019 BRCA-2_helical 60 lyslGvskkvleissenaesfkf 82 y G+++ v++ ss na+ f+ FUN_001311-T1 215 QYLEGIQEMVQMASSTNAHMFRV 237 6899*****************95 PP >> DUF2201 VWA-like domain (DUF2201) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 7.7e-05 0.33 1 65 [. 81 149 .. 81 163 .. 0.66 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.7e-05 DUF2201 1 lvlavDtSgSikdkelarfaaeladilrrleaevhvlafdeevqsaqrlep....asklaelqlkggGG 65 +++++D+S+S+++ e ar + l+d+ ++l+++ + a++ + +++ +++ + + l l++gGG FUN_001311-T1 81 VIIVLDSSSSVSKGEFARALIALQDLVKKLRNDTNYAAITYATRATTQFNFtnsfQTAKKLLALERGGG 149 6899*************************9777655555555444444433224333333445555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (282 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 954 (0.0373459); expected 510.9 (0.02) Passed bias filter: 622 (0.0243492); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2761.97 // Query: FUN_001311-T2 [L=272] Description: FUN_001311 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-24 87.6 2.9 2.1e-24 87.1 2.9 1.2 1 VWA von Willebrand factor type A domain 3e-15 57.2 0.4 1.1e-14 55.4 0.2 1.9 2 VWA_2 von Willebrand factor type A domain 0.00013 22.5 0.2 0.0003 21.4 0.2 1.5 1 VWA_3 von Willebrand factor type A domain 0.002 18.1 0.3 0.0025 17.8 0.3 1.1 1 VWA_CoxE VWA domain containing CoxE-like protein ------ inclusion threshold ------ 0.057 13.5 0.0 2.2 8.3 0.0 2.2 2 BRCA-2_helical BRCA2, helical 0.13 12.8 0.1 0.31 11.7 0.1 1.6 1 DUF2201 VWA-like domain (DUF2201) Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.1 2.9 5e-28 2.1e-24 1 172 [. 70 237 .. 70 239 .. 0.86 Alignments for each domain: == domain 1 score: 87.1 bits; conditional E-value: 5e-28 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrtefslndysskeellsavkslkykgggttntgkalkyalenlfkss 96 D++++lD+S+s+++++f ++ +l++lv++l ++t+++ ++y+++++t+f++++ + ++ l a++ +ggg+tnt +alk +e + ++ FUN_001311-T2 70 DVIIVLDSSSSVSKGEFARALIALQDLVKKLR---NDTNYAAITYATRATTQFNFTNSFQTAKKLLALE----RGGGKTNTQDALKRCQEMFVGDQ 158 9*******************************...**********************443233333444....4778888**********999999 PP VWA 97 agaRegapkvvvlltdGksqdg..dveeaarelksagvkvfavgv..gnadeeeLekiasepdeghvftvedfealeelq 172 gaR+g + ++++tdG+s+ + + + a +lk g++vf+++v +e+ ++as+++ h+f+v ++++l e++ FUN_001311-T2 159 YGARQGSLRRILVVTDGQSNINrdQTVTRAFQLKLLGIEVFVIAVgqYLEGIQEMVQMASSTN-AHMFRVLNMKNLVEVV 237 9******************88656777778888999*********433355677999999999.9*******99887765 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.4 0.2 2.6e-18 1.1e-14 1 108 [] 71 176 .. 71 176 .. 0.94 2 ? -1.0 0.0 0.89 3.8e+03 29 63 .. 211 250 .. 202 265 .. 0.55 Alignments for each domain: == domain 1 score: 55.4 bits; conditional E-value: 2.6e-18 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallkslpgd.rvglvtfsdnpevlipltkdkakllealrrleatgggtdlaaAlqlarkalkkrr.. 93 +++vlD+S S+++g ++++a a+++l+k+l++d +++ +t+++++++ +++t + +++++ l +le gg+t++++Al+ +++++ ++ FUN_001311-T2 71 VIIVLDSSSSVSKG-----EFARALIALQDLVKKLRNDtNYAAITYATRATTQFNFTNSFQTAKK-LLALERGGGKTNTQDALKRCQEMFVGDQyg 160 79************.....8***************9666******************98888775.8899989*****************999999 PP VWA_2 94 .rknakriivlitDge 108 r++ r+i+++tDg+ FUN_001311-T2 161 aRQGSLRRILVVTDGQ 176 999***********96 PP == domain 2 score: -1.0 bits; conditional E-value: 0.89 VWA_2 29 eallk...slpgdrvglvtfsd..npevlipltkdkakll 63 +++++ s + + ++++ + ++ +lip + k+ l+ FUN_001311-T2 211 QEMVQmasSTNAHMFRVLNMKNlvEVVKLIPNRGQKSWLE 250 4444433244566777777777444444455555555555 PP >> VWA_3 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.2 7e-08 0.0003 2 147 .. 70 218 .. 69 222 .. 0.79 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 7e-08 VWA_3 2 evvilvDvsss.msgeieavkdalklalrqLptndkinilvfgtkarplfpgsrtvssreldeaaqfvktlqpplGgtnllqaLkealrqk..... 91 +v+i++D+sss ++ge + al+ ++ L + + + + t ++++ + + + a +++ +l+ G tn + aLk + + FUN_001311-T2 70 DVIIVLDSSSSvSKGEFARALIALQDLVKKLRNDTNYAAITYATR---ATTQFNFTN--SFQTA-KKLLALERGGGKTNTQDALKRCQEMFvgdqy 159 89********977787677788889999***99998776666665...445555555..44555.555666666999**********999999999 PP VWA_3 92 .ekrgyvrsvilltdgsp.aqtservsdeisqargkirvhalglgstlsa.amLqeLAe 147 +++g+ r ++++tdg++ + ++ v + + i v+++++g+ l + + + ++A FUN_001311-T2 160 gARQGSLRRILVVTDGQSnINRDQTVTRAFQLKLLGIEVFVIAVGQYLEGiQEMVQMAS 218 *999**************667788888888778899**********7777777777776 PP >> VWA_CoxE VWA domain containing CoxE-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.3 5.8e-07 0.0025 40 186 .. 52 202 .. 41 236 .. 0.69 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 5.8e-07 VWA_CoxE 40 ggepvelvrrkpRkrkplrlvlllDvSgSmeaysavflallaAllrqfp.irtev.faFstrlvdlTdalderDpaeaLrrvsarved..vgGgTr 131 g+++++l r+ + l+++++lD S S+++ f++ l Al++ ++ +r + a t +++T +++ +++++ +++ gG T+ FUN_001311-T2 52 GHQTRRLYKRQVNLEDHLDVIIVLDSSSSVSK--GEFARALIALQDLVKkLRNDTnYAAITYATRATTQFN---FTNSFQTAKKLLALerGGGKTN 142 455666666666777889*************9..7788888899999996665442566777777777777...66666666433333326777** PP VWA_CoxE 132 igealaefrelvtrpaL...rrav..vlvvSDglegdareelleevaalrraarrlvwln 186 + al+ ++e + ++++ +lvv+Dg +r++ +++ +l+ ++ + +++ FUN_001311-T2 143 TQDALKRCQEMFVGDQYgarQGSLrrILVVTDGQSNINRDQTVTRAFQLKLLGIEVFVIA 202 **********99766543245665669******998888888887777777666666665 PP >> BRCA-2_helical BRCA2, helical # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.00052 2.2 84 128 .. 47 94 .. 29 130 .. 0.79 2 ? 3.3 0.0 0.017 74 60 82 .. 205 227 .. 146 246 .. 0.85 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00052 BRCA-2_helical 84 vedffgkell.legngiqLaD..ggllipddkgkvGkeefyralcdtp 128 ++f g+++ l ++ ++L D + ++++d++++v k ef ral++ FUN_001311-T2 47 NQNFLGHQTRrLYKRQVNLEDhlDVIIVLDSSSSVSKGEFARALIALQ 94 4667766654155688999998788999****************9865 PP == domain 2 score: 3.3 bits; conditional E-value: 0.017 BRCA-2_helical 60 lyslGvskkvleissenaesfkf 82 y G+++ v++ ss na+ f+ FUN_001311-T2 205 QYLEGIQEMVQMASSTNAHMFRV 227 6899*****************95 PP >> DUF2201 VWA-like domain (DUF2201) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 7.2e-05 0.31 1 65 [. 71 139 .. 71 153 .. 0.66 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 7.2e-05 DUF2201 1 lvlavDtSgSikdkelarfaaeladilrrleaevhvlafdeevqsaqrlep....asklaelqlkggGG 65 +++++D+S+S+++ e ar + l+d+ ++l+++ + a++ + +++ +++ + + l l++gGG FUN_001311-T2 71 VIIVLDSSSSVSKGEFARALIALQDLVKKLRNDTNYAAITYATRATTQFNFtnsfQTAKKLLALERGGG 139 6899*************************9777655555555444444433224333333445555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 958 (0.0375024); expected 510.9 (0.02) Passed bias filter: 630 (0.0246624); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2691.47 // Query: FUN_001312-T1 [L=767] Description: FUN_001312 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-23 82.5 0.0 3.4e-22 79.6 0.0 2.2 1 Peptidase_M28 Peptidase family M28 2.4e-22 79.7 0.1 9.7e-22 77.7 0.0 2.0 2 TFR_dimer Transferrin receptor-like dimerisation domain 2.1e-08 34.6 0.0 7.3e-08 32.9 0.0 1.9 2 PA PA domain ------ inclusion threshold ------ 0.023 15.8 0.2 0.1 13.7 0.1 2.1 2 MjAgo_N-like Archaeal argonaute protein N-terminal domain Domain annotation for each model (and alignments): >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.6 0.0 5.3e-26 3.4e-22 1 175 [. 381 583 .. 381 599 .. 0.80 Alignments for each domain: == domain 1 score: 79.6 bits; conditional E-value: 5.3e-26 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaa...skqqpkrsvrflffdaEEagllGSkafak..skpelkkiravl 90 Nv++++ g++e ++++++ H Ds++ GA D sg+ + e+ar l ++++p+r++ + +++EE+ l GS+ +++ ++ +++ +a++ FUN_001312-T1 381 NVVGTIVGRDEpHRYIIVGNHRDSWS--FGAVDALSGTTVTNEIARLLGMlleKGWRPRRTIKICSWGGEEFNLIGSHEWVEenAHILTERAVAYI 474 9**********888***********9..8*****************9987777999*************************976666********* PP Peptidase_M28 91 nlDmigsggkallfqsgpktsselekylkaaakpvgktlaedpfqerg..ipgr..............sDhapfakag.ipaldl.......aetk 162 nlD++ g+ l +++p ++ k+++++++p++ ++ +++++ +p++ sD+a+f ++ ip +d+ ++t+ FUN_001312-T1 475 NLDIAVCGDYVLRARTSPLFKQVTYKWARQVKNPQHLEANDTMYDIWLkrTPSDinsseprifnlfssSDYASFYQYLgIPSADFgywfgygSTTS 570 *****999999999666666666666666666666554433332211111122233445555555555******97644***************** PP Peptidase_M28 163 fkeryHtpkDtld 175 ++yHt++Dt+ FUN_001312-T1 571 LYPVYHTQQDTFY 583 **********985 PP >> TFR_dimer Transferrin receptor-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 0.53 3.4e+03 30 51 .. 352 375 .. 340 377 .. 0.75 2 ! 77.7 0.0 1.5e-25 9.7e-22 1 121 [] 645 763 .. 645 763 .. 0.95 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.53 TFR_dimer 30 vveas.gkessllavr.evNdklm 51 +++ g+++s+ +++ evN++l FUN_001312-T1 352 TYHVGpGFKNSSTKIKlEVNNQLQ 375 555566899999*********996 PP == domain 2 score: 77.7 bits; conditional E-value: 1.5e-25 TFR_dimer 1 lsleplkkaiekfkkaaeefdkwakkweevveasgkessllavrevNdklmlferafldpeglpgrpwfkHvvfapglwtg.yagatFPgirdaie 95 +sl+ l++ai+ f +++++f++ +++ + ++s+ ++r++Nd+++++e+af++p+glpg+ + +Hv f g ++ ++atFPg+++a++ FUN_001312-T1 645 ISLSALQDAITGFLDTSKRFESKKSDPT-------EHKSTSRLRMLNDQMVKVEKAFIYPYGLPGKIQSRHVAFNYGFHNLkPGKATFPGVTEALH 733 6899**********************88.......689999**************************************66688999********* PP TFR_dimer 96 a....gdweeaqkqisivakaiekaaesLk 121 +dw++a+kq+si+ + +++a + Lk FUN_001312-T1 734 MaeisNDWNTARKQVSIAIYSVQSANQVLK 763 999**********************99985 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.9 0.0 1.1e-11 7.3e-08 2 90 .. 203 284 .. 194 287 .. 0.82 2 ? -2.2 0.0 1.1 6.8e+03 80 95 .] 317 332 .. 307 332 .. 0.79 Alignments for each domain: == domain 1 score: 32.9 bits; conditional E-value: 1.1e-11 PA 2 tgplVaapndgceasdgssedf........dvkGkivLvqrGectfaeKvrnAqaaGAagviiynnvegglgapteaggeeleadpitiPavgisk 89 +++l+ +a+ g+ +df +v+G+iv++ + vrnA+++GAag+++y ++ + +a+++++ ++ +++ +++P+ g+++ FUN_001312-T1 203 EADLI-------YANFGRDQDFqklaemnvTVRGNIVII------RSRNVRNAEKHGAAGALVYADP--SFSAQKGYKSDQVYPNGWWLPSDGVQE 283 45555.......666776677777888999*********......688****************988..5456666778999*********99997 PP PA 90 a 90 + FUN_001312-T1 284 G 284 6 PP == domain 2 score: -2.2 bits; conditional E-value: 1.1 PA 80 itiPavgiskadgeal 95 iPa is++d+ +l FUN_001312-T1 317 PRIPAQAISYGDAMEL 332 78*********99876 PP >> MjAgo_N-like Archaeal argonaute protein N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 1.6e-05 0.1 4 50 .. 581 629 .. 578 632 .. 0.85 2 ? -1.6 0.0 0.95 6e+03 32 47 .. 689 704 .. 685 709 .. 0.81 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.6e-05 MjAgo_N-like 4 hfyriksfvneafnfyr.fvnfyggmiinkkdksfvlpykvdn..kvlky 50 fy +k fv++ f+ ++ + +f ggm+++ d+ +lp+ + n k lky FUN_001312-T1 581 TFYWVKKFVDQKFQVHKaMTQFSGGMLLDLADQP-LLPFDIMNyaKALKY 629 59************99835689*********997.599999875578888 PP == domain 2 score: -1.6 bits; conditional E-value: 0.95 MjAgo_N-like 32 kkdksfvlpykvdnkv 47 k +k+f+ py + k+ FUN_001312-T1 689 KVEKAFIYPYGLPGKI 704 789*******876665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (767 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 701 (0.0274418); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.40u 0.38s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7332.15 // Query: FUN_001316-T1 [L=1980] Description: FUN_001316 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-35 121.7 2.3 3.5e-35 120.7 2.3 1.4 1 AAA_lid_NAV1 NAV1-like, AAA+ ATPase lid domain 2.1e-05 24.9 0.0 0.00017 22.0 0.0 2.3 2 Ubiquitin_6 Neuron navigator 1-like, ubiquitin-like domain 0.00015 22.6 0.0 0.00057 20.7 0.0 2.0 1 AAA_22 AAA domain 0.00069 19.8 0.0 0.0014 18.8 0.0 1.5 1 nSTAND3 Novel STAND NTPase 3 0.0015 19.3 0.4 0.0061 17.3 0.0 2.2 2 NPHP3_N Nephrocystin 3, N-terminal 0.0024 18.2 0.0 0.0052 17.1 0.0 1.6 1 NACHT NACHT domain 0.0026 18.8 0.1 0.009 17.0 0.1 1.9 1 AAA_16 AAA ATPase domain 0.0043 17.2 0.0 0.0094 16.1 0.0 1.5 1 AAA_25 AAA domain ------ inclusion threshold ------ 0.016 15.7 0.0 0.034 14.7 0.0 1.5 1 nSTAND6 Novel STAND NTPase 6 0.023 15.0 0.0 0.066 13.5 0.0 1.7 1 RsgA_GTPase RsgA GTPase 0.026 15.5 0.0 0.068 14.2 0.0 1.7 1 RNA_helicase RNA helicase 0.039 14.9 0.0 0.1 13.6 0.0 1.7 1 AAA ATPase family associated with various cellular 0.073 14.0 0.0 0.44 11.5 0.0 2.5 1 AAA_18 AAA domain 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 PhoH PhoH-like protein Domain annotation for each model (and alignments): >> AAA_lid_NAV1 NAV1-like, AAA+ ATPase lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 120.7 2.3 1.9e-38 3.5e-35 5 109 .. 1811 1915 .. 1807 1920 .. 0.96 Alignments for each domain: == domain 1 score: 120.7 bits; conditional E-value: 1.9e-38 AAA_lid_NAV1 5 rksserkkelakiidwlpkvwqhlnkflekhsssdvtigprlflscPldveesreWFidlWneslvPylleavreglqlygrraawedptewvl 98 +++++ +l +++dwl+kvw+hln +le++ + d+tigp++f+scP+d+ +++ WF+ +Wn+++vP+l++a+r+g +++ r+ +wedpt+wv FUN_001316-T1 1811 LQNKAEGDDLLQLFDWLTKVWYHLNGILEEYCEPDTTIGPSVFFSCPMDFIAAEGWFVTVWNYNVVPHLHQALRSGRKIFDRCISWEDPTKWVA 1904 67888999************************************************************************************** PP AAA_lid_NAV1 99 etyPWseaksk 109 ++yPW++++s+ FUN_001316-T1 1905 QRYPWNKDQSR 1915 ******99875 PP >> Ubiquitin_6 Neuron navigator 1-like, ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1 1.9e+03 14 54 .. 1387 1429 .. 1380 1448 .. 0.74 2 ! 22.0 0.0 9.1e-08 0.00017 22 77 .. 1543 1597 .. 1522 1625 .. 0.90 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1 Ubiquitin_6 14 eeaklkedakqqefliGsigvsgk...tkWdvLDgvvrrlFkey 54 e+++++e+ ++ ++l+G ++ s + ++ d+LD+++ + Fk+ FUN_001316-T1 1387 ESESTEEEDNHLDILLGEVRRSLNlefVDSDILDKAIEK-FKQR 1429 45567778888899*****99988223456899999976.6654 PP == domain 2 score: 22.0 bits; conditional E-value: 9.1e-08 Ubiquitin_6 22 akqqefliGsigvsgktkWdvLDgvvrrlFkeyilkvDpasslGLssdsvasYsig 77 +k++e +G ++v g ++W+ + ++ rr F ++i ++Dp lGL + s+++ + g FUN_001316-T1 1543 SKKNETHLGKVTVKG-ADWSGVIEAARRAFVDHIQRIDPDNYLGLGVHSIQGVQTG 1597 5788899******99.69********************************997765 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 3.1e-07 0.00057 6 64 .. 1659 1721 .. 1656 1745 .. 0.82 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 3.1e-07 AAA_22 6 gilvltGesGtGKTtllrrlleqldee.....ddsvvlvelpsstspkdllrellralglelek 64 + +vl+Ge G GK++l+ +l+e +++ ++ v +++++ t +k+l ++l++ +++++++ FUN_001316-T1 1659 RYIVLCGEQGLGKSYLATKLAEHVVQRiackaSPAVAIFNVAQAT-RKELNKNLASLMQNDAPS 1721 679*********************999**9966666677777777.*************99988 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 7.9e-07 0.0014 4 44 .. 1645 1685 .. 1642 1711 .. 0.82 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 7.9e-07 nSTAND3 4 tkafekaleiLeknkvviitGepGiGKttlaemLalkllde 44 + +ek +e L ++++++++Ge G GK+ la La +++++ FUN_001316-T1 1645 KETIEKYVEQLLEHRYIVLCGEQGLGKSYLATKLAEHVVQR 1685 5678999****************************999885 PP >> NPHP3_N Nephrocystin 3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 6 1.1e+04 54 103 .. 329 378 .. 320 401 .. 0.68 2 ! 17.3 0.0 3.3e-06 0.0061 7 80 .. 1643 1719 .. 1639 1745 .. 0.82 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 6 NPHP3_N 54 ayfffdfsdeekqslssllrsllhqlas.qlpelreelleklaedlgldek 103 ++ +d+++++++++ ++ +s++ +s + ++++++l++k ++ +++e+ FUN_001316-T1 329 QCLVCDNDNNNSTEAVNASQSVVITSFSgRVQDYSDHLVNKGLRR-SIHEN 378 677899999999999999999887765525778888887764432.33333 PP == domain 2 score: 17.3 bits; conditional E-value: 3.3e-06 NPHP3_N 7 ledeefqeWldspsdssllwlsGkpGsGKsvlastvidhlqae...gsavayfffdfsdeekqslssllrsllhqla 80 l +e++++ +++ +++ + l G+ G GKs+la+ +++h+ ++ + + a+ f+ ++++++l++ l+sl+ a FUN_001316-T1 1643 LPKETIEKYVEQLLEHRYIVLCGEQGLGKSYLATKLAEHVVQRiacKASPAVAIFNVAQATRKELNKNLASLMQNDA 1719 5666777777777788999********************9765443667899*******************987655 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 2.9e-06 0.0052 1 70 [. 1659 1727 .. 1659 1743 .. 0.84 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 2.9e-06 NACHT 1 rtvilqGeaGsGKTtLlqklalawaegklpqdafklvFflslrelsrsgkalsladllfsqlpepaapvs 70 r+++l Ge+G GK++L+ kla ++ + a + v +++++ +r++ la+l+ ++ p+ ++ + FUN_001316-T1 1659 RYIVLCGEQGLGKSYLATKLAEHVVQRIACK-ASPAVAIFNVAQATRKELNKNLASLMQNDAPSFTESRP 1727 689********************99987544.58*************99888999988887777666555 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.1 4.9e-06 0.009 11 81 .. 1647 1708 .. 1645 1752 .. 0.69 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 4.9e-06 AAA_16 11 aLlallervrsgrpplvlvsGeaGvGKSalvrellraleraalvlsgkcdelqrglpyaallealtresll 81 ++++++e+ ++ +++++ Ge+G GKS l+ +l++++ ++ + +k+ ++ +++a r++l FUN_001316-T1 1647 TIEKYVEQLLEH--RYIVLCGEQGLGKSYLATKLAEHVVQR---IACKASPA---VAIFNVAQAT-RKELN 1708 566777777787..79***********************99...77777776...2222233333.32333 PP >> AAA_25 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 5.1e-06 0.0094 18 59 .. 1644 1684 .. 1635 1741 .. 0.83 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 5.1e-06 AAA_25 18 rppplrwlikgllpagelillaGapgtGKttlaldlalavat 59 + + +++++ ll ++ i+l+G g GK++la+ la +v + FUN_001316-T1 1644 PKETIEKYVEQLL-EHRYIVLCGEQGLGKSYLATKLAEHVVQ 1684 56778999****9.7***********************9984 PP >> nSTAND6 Novel STAND NTPase 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 1.8e-05 0.034 6 75 .. 1646 1719 .. 1644 1732 .. 0.83 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.8e-05 nSTAND6 6 kllkklvakLkekpillvyGlrGnGKstlieelg....kkaalkgkeavrisasrqltadelFrqladlLgets 75 + ++k v++L e+ +++ G +G GKs l +l+ ++ a k av i +q t +el ++la+l+++ + FUN_001316-T1 1646 ETIEKYVEQLLEHRYIVLCGEQGLGKSYLATKLAehvvQRIACKASPAVAIFNVAQATRKELNKNLASLMQNDA 1719 5799**********************988777761111455666688899*9*****************99875 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 3.6e-05 0.066 98 134 .. 1650 1686 .. 1633 1690 .. 0.84 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 3.6e-05 RsgA_GTPase 98 eelkellkgkttvllGqSGvGKStLinallpelelkt 134 + +++ll+++ +vl+G+ G GKS L +l+++ +++ FUN_001316-T1 1650 KYVEQLLEHRYIVLCGEQGLGKSYLATKLAEHVVQRI 1686 357888999********************99988776 PP >> RNA_helicase RNA helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 3.7e-05 0.068 1 41 [. 1661 1701 .. 1661 1736 .. 0.83 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 3.7e-05 RNA_helicase 1 iwlyGpsgeGKStlakelakallkklklpkkdsvysrnped 41 i+l+G++g GKS+la++la+++ +++ + ++ v + n ++ FUN_001316-T1 1661 IVLCGEQGLGKSYLATKLAEHVVQRIACKASPAVAIFNVAQ 1701 799*********************99877777776666555 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 5.5e-05 0.1 1 71 [. 1661 1740 .. 1661 1748 .. 0.65 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 5.5e-05 AAA 1 lllyGppGtGKTllakavakel........gaefveisgselvskyvgesekklrelfee.akkka......psvifiDEiDalak 71 ++l+G +G GK++la +a+++ + + +++ + + +e +k+l+ l+++ a p v+++D + la+ FUN_001316-T1 1661 IVLCGEQGLGKSYLATKLAEHVvqriackaSPAVAIFNVAQAT---RKELNKNLASLMQNdA---PsftesrPAVVVLDQLNCLAS 1740 579******************7332222211223333333333...5566666666666633...03456669******9988875 PP >> AAA_18 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.00024 0.44 1 92 [. 1661 1747 .. 1661 1762 .. 0.76 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00024 AAA_18 1 IlitGtpGvGKttlareLserlgfgdnvrdlakenglvlsddeetdeskrldedklaklldeleelas....leeggnlvidghlaelfperlr 90 I+++G G GK+ la L+e+ v+ +a + + + + +++l+k+l l+++++ +++ ++v+d++++ + + FUN_001316-T1 1661 IVLCGEQGLGKSYLATKLAEHV-----VQRIACKASPAVAIFNV----AQATRKELNKNLASLMQNDApsftESRPAVVVLDQLNCLASLADVF 1745 89******************96.....55555554445555555....3335555577888888887788888889999999999988888777 PP AAA_18 91 dl 92 dl FUN_001316-T1 1746 DL 1747 76 PP >> PhoH PhoH-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00014 0.26 10 46 .. 1649 1685 .. 1644 1695 .. 0.90 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00014 PhoH 10 keyvealkkndivfaiGpaGtGKtylavalavealke 46 ++yve+l ++ ++ +G+ G GK+yla+ la +++++ FUN_001316-T1 1649 EKYVEQLLEHRYIVLCGEQGLGKSYLATKLAEHVVQR 1685 79***************************99888775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1980 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1211 (0.0474065); expected 510.9 (0.02) Passed bias filter: 654 (0.0256019); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.62u 0.39s 00:00:01.01 Elapsed: 00:00:00.43 # Mc/sec: 18687.82 // Query: FUN_001317-T1 [L=667] Description: FUN_001317 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-16 58.6 3.4 4.4e-12 46.4 2.9 2.1 2 Sec1 Sec1 family ------ inclusion threshold ------ 0.41 11.6 3.5 3.2 8.7 0.4 2.5 2 CLAMP Flagellar C1a complex subunit C1a-32 Domain annotation for each model (and alignments): >> Sec1 Sec1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 2.5e-05 0.32 140 217 .. 204 274 .. 170 279 .. 0.76 2 ! 46.4 2.9 3.4e-16 4.4e-12 275 576 .] 347 655 .. 340 655 .. 0.61 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 2.5e-05 Sec1 140 eieelldriakgLlsvlltlekkiPiirykgpaaemvakkladklrdeidskenfledsskprpvLlIlDRsvDlvtp 217 + + ++ a gL + l+ l+++ ++ g ++ +a++la++ ++ + + +s k+r L+++DR++Dlv p FUN_001317-T1 204 NLQLKIKMFAFGLNN-LFELLEVNEDCYGVGYLSKVIATELANLPAARMRR------KSAKSRGSLILIDRTLDLVGP 274 455566667777777.44453567778888888999999999999988875......46899*************977 PP == domain 2 score: 46.4 bits; conditional E-value: 3.4e-16 Sec1 275 geklkkklkelkaknaelkrk.gakssesiadlkdfvekLpelqeekkklslHtnlaee.llkiikk..rkldellelEqdlat..gegd.kkqke 363 + +l+++lke +k++ l+++ +++s+ ++++lk + e++ + + kk s ++l+ + ++ +++ + del lE+ l+ +e +++ FUN_001317-T1 347 MVDLSRQLKEALNKESLLQTSkDVQSKVTVEQLKMMTEHFRGQPKCMKKHSALLQLVRAaIMALTSEniSHMDELQALEKGLILhvSEHGpQSS-L 441 5567778888877777777776788899********998666555555555555555432444444477899************7644342333.3 PP Sec1 364 kklieelial.depvseledk.lRLlllysltenglkskdleelkrellqsaly...............gleylktlknlekagllkkkkskkssk 442 ++++ + a+ +++ ++ed+ l L+ lyslt + ++ +ee+ ++++ +++ g +l+k+ ++ s FUN_001317-T1 442 SQVMKTFQADkQQKFVNIEDIlLILIYLYSLTGQECYNSPIEEE--QMISMVINsilsgelkcssesflG------------SDILEKTVRSRISD 523 34555555557555555566615677899998434445555544..223323344445544443332221............33332222222111 PP Sec1 443 kkss.........klklkkkevdeeenyd.ysgvsryaPllkrlvesllkgkllsseepslktldasseesskssssessakkskskssgskrkkk 528 + + ++ +d + + +++ +y Pl+k++v+ +++ + +++ + ++ +++ + ++ s + ++ r+++ FUN_001317-T1 524 ---AfekvrgvnlARAELQMFRDVFQHGTaLKQ-AQYRPLVKQIVDGIFN-PESPELPDVEFKSHGLK--------DFIKTGFSLFMNVSKPRPNN 606 ...022234444422223333333333324333.48**************.77777777665555543........45666666666777777777 PP Sec1 529 kqrviVfvvGGvTysEiral.rllnkqkknkeviigstsilnpksfles 576 + ++ fvvGG+T sE+ + + l++ + n + +igst +l++++++++ FUN_001317-T1 607 HPLLVLFVVGGITCSEVYQIrEALAAYHPNTQLLIGSTRLLKANDLFNQ 655 899*****************777776578999************99876 PP >> CLAMP Flagellar C1a complex subunit C1a-32 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.2 0.015 2e+02 25 76 .. 333 386 .. 331 389 .. 0.83 2 ? 8.7 0.4 0.00025 3.2 14 66 .. 394 450 .. 391 471 .. 0.81 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.015 CLAMP 25 klleklisk.plenleesfklfkelllkhsverppssig.iFsleqvkaiidYl 76 +ll +i+k + e++ ++ +++ke+l k s+ + ++++ ++eq+k +++++ FUN_001317-T1 333 ALLCSMITKrQKETMVDLSRQLKEALNKESLLQTSKDVQsKVTVEQLKMMTEHF 386 56667777756678999*************99998888778999**99999998 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00025 CLAMP 14 eqtsaflsilkkllekliskplenleesfklfkelllkhsverppssig....iFsl 66 +++sa+l+++ + + +l s+++++++e+ +l k l+l s + p+ss+ F+ FUN_001317-T1 394 KKHSALLQLVRAAIMALTSENISHMDELQALEKGLILHVSEHGPQSSLSqvmkTFQA 450 789*******************99999999999999999999999988765554433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (667 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1190 (0.0465845); expected 510.9 (0.02) Passed bias filter: 819 (0.0320611); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.40 # Mc/sec: 6756.85 // Query: FUN_001318-T1 [L=247] Description: FUN_001318 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (247 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1385 (0.054218); expected 510.9 (0.02) Passed bias filter: 637 (0.0249364); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2462.05 // Query: FUN_001319-T1 [L=77] Description: FUN_001319 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (77 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 381 (0.0149149); expected 510.9 (0.02) Passed bias filter: 338 (0.0132316); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.34s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 802.28 // Query: FUN_001320-T1 [L=515] Description: FUN_001320 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-10 41.9 0.6 3e-10 40.6 0.1 1.9 2 Mab-21_C Mab-21 protein HhH/H2TH-like domain ------ inclusion threshold ------ 0.04 14.2 0.0 0.14 12.4 0.1 1.9 2 DUF2689 Protein of unknown function (DUF2689) 0.14 12.7 0.0 0.2 12.2 0.0 1.2 1 Mab-21 Mab-21 protein nucleotidyltransferase domain Domain annotation for each model (and alignments): >> Mab-21_C Mab-21 protein HhH/H2TH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.6 0.1 3.5e-14 3e-10 3 90 .. 334 426 .. 332 438 .. 0.81 2 ? -1.8 0.0 0.58 5e+03 61 79 .. 446 465 .. 435 468 .. 0.69 Alignments for each domain: == domain 1 score: 40.6 bits; conditional E-value: 3.5e-14 Mab-21_C 3 kkclrllkklkekkkrdvkkeleklksyhlktlllwecekkp.....ddseWeekklkerllellekLkkclrkrklphyFipklnLleelsk 90 k c++++k ++ +++++k+++ lksyhlkt++lw e++ + ++k ++ +ll+++ +++++ + l+hyFi+++n+le + FUN_001320-T1 334 KLCYNIIKFAVKQFSQRKHKSYPALKSYHLKTVILWIAEQNGkvpfdMYTINNNKTMGALLLHVISTYRQHIHAGYLQHYFIRDINILEPYGV 426 6688888877665566668999******************9444443333346789********************************87655 PP == domain 2 score: -1.8 bits; conditional E-value: 0.58 Mab-21_C 61 llekLkk.clrkrklphyFi 79 ++ k+ k l++ kl+++Fi FUN_001320-T1 446 IVLKFDKaNLSQWKLEQFFI 465 55666552578888888887 PP >> DUF2689 Protein of unknown function (DUF2689) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 1.6e-05 0.14 12 38 .. 190 216 .. 187 220 .. 0.93 2 ? -3.0 0.0 1.1 8.9e+03 23 39 .. 232 248 .. 227 253 .. 0.65 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.6e-05 DUF2689 12 vPdesvqddfvkyvisncttkiilsGr 38 v d+ qd+f+k i c t +lsGr FUN_001320-T1 190 VADQFRQDEFLKDCIVRCGTESLLSGR 216 779999********************9 PP == domain 2 score: -3.0 bits; conditional E-value: 1.1 DUF2689 23 kyvisncttkiilsGrr 39 y t k il G r FUN_001320-T1 232 EYNYPAMTFKAILHGPR 248 45555567777777755 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 2.3e-05 0.2 125 196 .. 256 325 .. 211 326 .. 0.83 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 2.3e-05 Mab-21 125 dlvpaielkasWpksasnwprclkrwpsqkvlekiksegfhlvakssykdqdekeedsWrlSFseaEkaLLk 196 d+v+ i++++ +w +++++ ++l++i++ g+++v k ++++ Wr+ F eaE +L++ FUN_001320-T1 256 DVVFGIKIQNPE-DIIYDWFIRVQNAFPNQLLNSIRALGCYIVHKHCL-SNHSSHDFDWRITFAEAESKLFE 325 889999999933.345669**************************655.355888999***********997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (515 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1166 (0.0456449); expected 510.9 (0.02) Passed bias filter: 542 (0.0212175); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5088.54 // Query: FUN_001321-T1 [L=109] Description: FUN_001321 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (109 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 514 (0.0201214); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.38 # Mc/sec: 1142.07 // Query: FUN_001322-T1 [L=354] Description: FUN_001322 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-75 255.2 0.6 1.4e-75 255.0 0.6 1.0 1 PfkB pfkB family carbohydrate kinase 0.00052 20.0 0.0 0.0011 18.8 0.0 1.6 1 Phos_pyr_kin Phosphomethylpyrimidine kinase ------ inclusion threshold ------ 0.03 14.9 0.2 0.22 12.2 0.0 2.1 2 Cas12f1-like_TNB Cas12f1-like, TNB domain 0.17 12.8 0.3 5.7 7.9 0.1 2.4 2 EGF_alliinase Alliinase EGF-like domain Domain annotation for each model (and alignments): >> PfkB pfkB family carbohydrate kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 255.0 0.6 2.2e-79 1.4e-75 12 297 .. 46 347 .. 36 352 .. 0.95 Alignments for each domain: == domain 1 score: 255.0 bits; conditional E-value: 2.2e-79 PfkB 12 idlianeekl...egelvevstvektaGGkgaNvAvalarlg....akvaflgavGdDnfgefllqelkkegvdtsyvkidedtrtglalievded 100 + +i++eek+ ++ ve +ve+ +GG+++N+++++++l ++++++g+vG+D+fg+ l+++ +++gv ++y++ de+ +tg+++++++++ FUN_001322-T1 46 NNAILAEEKHktiYKKMVEKFNVEYIPGGATQNSMRVAQWLLgsdtKSTSYIGCVGKDEFGKILAEKANEAGVHVNYLIHDEE-STGTCAVCITGK 140 667888888889888999************************9************************************6666.**********97 PP PfkB 101 gertivfnrgaaadltkeele..enedlleeadllyisgllskelpeaaleelaeaaknagtfdpvlldplgss.akeallellpladllkpNeeE 193 r++v+n++aa+ ++k++l+ en++ +e+a+++yi+g++ +++ e++++ ++aa++++tf+++l++p+ + +k++++e++p++d+l++Ne+E FUN_001322-T1 141 -HRSLVANLAAANCYKKSHLDqpENWAFVEKAKYIYIGGFFLTVSIESIVAVGKHAAEKNKTFIMNLSAPFLCQfYKKQMMEAMPYVDILFGNETE 235 .8********************************************************************************************** PP PfkB 194 lealtgakl......edieealkalhkllakgaktvvvtlGaeGalvve..kdgevkvpavpkvkvvDttGAGDsfvggflaallegksleeavrf 281 + +++++++ ++i+ + al+k+++++ + vv+t+G+e+a++v+ k++e+++ ++++++vDt+GAGD+fvggfl++l++g+s++e+vr+ FUN_001322-T1 236 AGIFAKEQDfetedlKEIALKMCALPKVNQSRSRLVVITHGKEPAIAVKdgKVTEYPAVLIKEEEIVDTNGAGDAFVGGFLSQLAKGNSIAECVRC 331 *********99999999999999**************************666677777777*********************************** PP PfkB 282 anaaAalvvqkkgaqa 297 +++aA ++q++g++ FUN_001322-T1 332 GHYAANYMIQQSGVTL 347 *************986 PP >> Phos_pyr_kin Phosphomethylpyrimidine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 1.8e-07 0.0011 114 233 .. 220 340 .. 203 352 .. 0.74 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 1.8e-07 Phos_pyr_kin 114 keeLlplatvvTPNlpEaeaLlgkkikteedmkeaakkllel......gakavlikGghlegeeavvtdvlydgeeveeleaerietknthGtGct 203 e +p ++++ N Ea +++++ ++ed+ke a k+++l ++ v+i+ g+ v+d +++ +++e i +t+G+G++ FUN_001322-T1 220 M-EAMPYVDILFGNETEAGIFAKEQDFETEDLKEIALKMCALpkvnqsRSRLVVITHGKE--PAIAVKDGKVTEYPAVLIKEEEIV--DTNGAGDA 310 2.36799****************6666677777777776664444443677888888874..455557888888888888877777..89****** PP Phos_pyr_kin 204 lsaaiaaelakgesleeAvkeAkefvteai 233 + ++lakg+s+ e v+ ++ + i FUN_001322-T1 311 FVGGFLSQLAKGNSIAECVRCGHYAANYMI 340 *******************97765544444 PP >> Cas12f1-like_TNB Cas12f1-like, TNB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 3.4e-05 0.22 3 37 .. 104 142 .. 103 161 .. 0.68 2 ? 0.1 0.0 0.2 1.3e+03 30 37 .. 327 334 .. 313 349 .. 0.66 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.4e-05 Cas12f1-like_TNB 3 qfrqmleyKaeeagievvkvdpay.TSqtCskCg...lk 37 +f ++l+ Ka+eag++v + ++ tC +C ++ FUN_001322-T1 104 EFGKILAEKANEAGVHVNYLIHDEeSTGTCAVCItgkHR 142 6889**************6554444*******9643333 PP == domain 2 score: 0.1 bits; conditional E-value: 0.2 Cas12f1-like_TNB 30 tCskCglk 37 +C +Cg+ FUN_001322-T1 327 ECVRCGHY 334 56666654 PP >> EGF_alliinase Alliinase EGF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.049 3.1e+02 25 50 .. 119 144 .. 114 149 .. 0.83 2 ? 7.9 0.1 0.00089 5.7 17 42 .. 303 331 .. 297 336 .. 0.85 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.049 EGF_alliinase 25 ylDglvldgkpvCECnsCfaGkDCSl 50 ++ l+ d +++ C C +Gk Sl FUN_001322-T1 119 HVNYLIHDEESTGTCAVCITGKHRSL 144 667778899999*********98776 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00089 EGF_alliinase 17 sCSGhGraylDglv..l.dgkpvCECnsC 42 + G G a++ g++ l +g+++ EC +C FUN_001322-T1 303 DTNGAGDAFVGGFLsqLaKGNSIAECVRC 331 5679********98552599********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (354 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 752 (0.0294382); expected 510.9 (0.02) Passed bias filter: 592 (0.0231748); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3521.64 // Query: FUN_001323-T1 [L=747] Description: FUN_001323 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.01 16.3 6.1 0.01 16.3 6.1 2.7 2 CCDC24 Coiled-coil domain-containing protein 24 family 0.028 15.0 5.5 0.13 12.8 5.5 2.2 1 Prefoldin_3 Prefoldin subunit 0.21 13.3 12.1 4.8 8.9 2.8 4.5 5 DUF5320 Family of unknown function (DUF5320) 0.31 11.3 12.3 0.072 13.4 4.7 3.4 3 SKA2 Spindle and kinetochore-associated protein 2 0.66 10.7 4.4 1.1 9.9 2.9 2.0 1 PHM7_cyt Cytosolic domain of 10TM putative phosphate tra 1.2 9.6 15.8 0.035 14.5 6.8 3.1 3 WWC1 WWC1-like, helical hairpin 2.3 8.1 20.3 0.72 9.7 13.5 3.1 3 GAS Growth-arrest specific micro-tubule binding 2.7 8.7 9.7 8.1 7.1 5.4 3.3 2 DUF7365 Coiled-coil region of unknown function (DUF7365 4.3 8.4 6.6 55 4.8 2.6 3.3 3 DUF2935 Domain of unknown function (DUF2935) 6.5 7.5 17.2 0.1 13.3 8.0 2.9 3 Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 8.1 7.2 17.7 1.4 9.6 0.1 5.2 5 REST_helical Helical region in REST corepressor Domain annotation for each model (and alignments): >> CCDC24 Coiled-coil domain-containing protein 24 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.3 6.1 4.5e-06 0.01 101 181 .. 518 599 .. 469 605 .. 0.79 2 ? 2.1 0.2 0.1 2.3e+02 155 189 .. 597 631 .. 596 632 .. 0.86 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 4.5e-06 CCDC24 101 eeeespssrPeteisqlssassnsssdrelkeikdkL.NvsdidqvaehLRelLeeEceaLerdIeyLqecleeelslakev 181 e++ s +r +t+ ++ ++++ ++++elk++kd+L +++ + Re Le E ++ ++ I +Lq++le++++++ e+ FUN_001323-T1 518 ERTDSTNQRNQTPEPNAGASEELRNLHEELKSVKDQLfEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQDEM 599 44555556666666666677999*************95566666677788***************************99887 PP == domain 2 score: 2.1 bits; conditional E-value: 0.1 CCDC24 155 eEceaLerdIeyLqecleeelslakevseaakePs 189 E++ L+r+++ L +++e++ ++ +e+ ++ Ps FUN_001323-T1 597 DEMAYLKRQVKSLTNQIEQQQQRITELRFRSSSPS 631 7999****************999998886677776 PP >> Prefoldin_3 Prefoldin subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 5.5 5.7e-05 0.13 16 98 .. 535 620 .. 521 621 .. 0.83 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 5.7e-05 Prefoldin_3 16 glkeeiealkeeddatkedllriarefegslvnekEikeilGekqgvtrs.kqQvvdlis..rRiDYVkqniktlekrleaaenkl 98 g ee+++l+ee ++ k++l +i++e ++ l+ ++E+++ l +k+ + r ++Q+ + + + Y k+ +k+l+ ++e++++++ FUN_001323-T1 535 GASEELRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMlQKQLESQSDsqDEMAYLKRQVKSLTNQIEQQQQRI 620 6789*********************************99888877666651566666554114688**************999875 PP >> DUF5320 Family of unknown function (DUF5320) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 6.4 1.5e+04 45 78 .. 32 66 .. 23 78 .. 0.56 2 ? -2.0 0.0 5.3 1.2e+04 65 96 .. 81 112 .. 69 113 .. 0.74 3 ? 0.9 0.0 0.66 1.5e+03 15 53 .. 138 178 .. 134 197 .. 0.64 4 ? 6.0 0.0 0.016 38 47 98 .. 507 556 .. 481 563 .. 0.60 5 ? 8.9 2.8 0.0021 4.8 64 99 .] 588 623 .. 574 623 .. 0.87 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 6.4 DUF5320 45 gfgRgfgrrrlaggagla.aaaaqeaskeeekelL 78 g+ R fg+ + + ++ + ++++++ ++ + L FUN_001323-T1 32 GYLRSFGFANTNPSSKTEsSEDNTQQTEVTNDTQL 66 56666666555444444443444444444444444 PP == domain 2 score: -2.0 bits; conditional E-value: 5.3 DUF5320 65 aaqeaskeeekelLkeqaelLeeeLeaikkrL 96 + ++++ke+ l ++q+++L +L +i +++ FUN_001323-T1 81 KDDNVTKEQHSILSESQINMLSFNLWEIADKI 112 56667777777777889999999998888776 PP == domain 3 score: 0.9 bits; conditional E-value: 0.66 DUF5320 15 mtGrglGyCagaaapgyansaglGr.Grg.grgfgRgfgrr 53 m+ + +G+C +++++ +++ + r G +++ f r+ FUN_001323-T1 138 MSSQTFGTCDDEQTSRFKTPYSRQRrGSKtFASRQKSFTRK 178 788899****9999988887555553444333444444443 PP == domain 4 score: 6.0 bits; conditional E-value: 0.016 DUF5320 47 gRgfgrrrlaggaglaaaaaqeaskeeekelLkeqaelLeeeLeaikkrLee 98 g gfg++ ++ ++ ++q++++ e ++ e+ ++L eeL+++k++L e FUN_001323-T1 507 GDGFGNSKNVTERTDS--TNQRNQTPEPNAGASEELRNLHEELKSVKDQLFE 556 4455554444444443..4555555555555666666777777777766644 PP == domain 5 score: 8.9 bits; conditional E-value: 0.0021 DUF5320 64 aaaqeaskeeekelLkeqaelLeeeLeaikkrLeel 99 + ++++++++e ++Lk+q++ L +++e+ ++r+ el FUN_001323-T1 588 QLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITEL 623 4568999**************************986 PP >> SKA2 Spindle and kinetochore-associated protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 0.48 1.1e+03 39 63 .. 421 445 .. 413 450 .. 0.79 2 ? 13.4 4.7 3.1e-05 0.072 38 105 .. 538 601 .. 523 606 .. 0.73 3 ? -1.1 0.0 0.97 2.3e+03 6 30 .. 668 692 .. 664 700 .. 0.82 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.48 SKA2 39 npvkLlerlkklkeelqaLkeqcee 63 +++l++lk k++l +Lk++ +e FUN_001323-T1 421 GFMQMLTDLKSFKTQLLKLKRELQE 445 4789999999999999999998887 PP == domain 2 score: 13.4 bits; conditional E-value: 3.1e-05 SKA2 38 enpvkLlerlkklkeelqaLkeqceellaekqelvdkirttLvsnrellqqLqasaelpplteeeqea 105 e++++L+e+lk +k++l ++ ++ + +l +++e +++ L s+ +++++Lq+++e ++ +++e ++ FUN_001323-T1 538 EELRNLHEELKSVKDQLFEITKERDSVLIAREE----LEHELDSKNHTIRMLQKQLESQSDSQDEMAY 601 556666666666666666666666666666655....5789999****************99999776 PP == domain 3 score: -1.1 bits; conditional E-value: 0.97 SKA2 6 klealfqkAesdLdyvqhrLdkefk 30 +l + qkAe++++++q+ L + f+ FUN_001323-T1 668 QLSKYIQKAEQNISMAQKGLSSFFS 692 5778899*********999987765 PP >> PHM7_cyt Cytosolic domain of 10TM putative phosphate transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 2.9 0.00047 1.1 44 119 .. 554 622 .. 543 647 .. 0.78 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00047 PHM7_cyt 44 ldklveerekavrkleaalakylkngkklpkkrpthklgflglkligkkvdaidyytekleeleeeieeerekvkk 119 l ++ +er+ ++ + e+ ++++++++ t+++ +l + + d + y+++++++l+ +ie++++++++ FUN_001323-T1 554 LFEITKERDSVLIAREELEHELDSKN-------HTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITE 622 55677888888888888877776654.......4666666667777899***********************9954 PP >> WWC1 WWC1-like, helical hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 4.3 1e+04 73 90 .. 430 447 .. 424 454 .. 0.61 2 ? 14.5 6.8 1.5e-05 0.035 61 134 .. 522 595 .. 518 596 .. 0.95 3 ? -0.6 0.2 0.7 1.6e+03 72 90 .. 599 617 .. 594 627 .. 0.48 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 4.3 WWC1 73 ekleeekkrLeedlqsar 90 ++ + + +L+++lq+a FUN_001323-T1 430 KSFKTQLLKLKRELQEAE 447 444555556666666664 PP == domain 2 score: 14.5 bits; conditional E-value: 1.5e-05 WWC1 61 sispkkrseeelekleeekkrLeedlqsarelsskaiadRlklqeekkkLlqqLeeatrlttlLesqLkslSas 134 s +++++++e + ee ++L e+l+s+++ + ++R ++ +++L ++L + ++ +L++qL s S s FUN_001323-T1 522 STNQRNQTPEPNAGASEELRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDS 595 567899999999999*********************************************************98 PP == domain 3 score: -0.6 bits; conditional E-value: 0.7 WWC1 72 lekleeekkrLeedlqsar 90 ++ l+ + k L++++++ + FUN_001323-T1 599 MAYLKRQVKSLTNQIEQQQ 617 4444444444444443332 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 0.69 1.6e+03 86 105 .. 428 447 .. 416 498 .. 0.71 2 ? 9.7 13.5 0.00031 0.72 28 112 .. 540 624 .. 537 629 .. 0.91 3 ? 0.4 0.0 0.22 5.2e+02 47 78 .. 657 688 .. 641 696 .. 0.81 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.69 GAS 86 slknlkarlkelekelkelk 105 +lk+ k++l +l++el+e + FUN_001323-T1 428 DLKSFKTQLLKLKRELQEAE 447 45566666666666665554 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00031 GAS 28 ikslKeeiaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknlkarlkelekelkelkwehevle 112 ++l ee++ +k + e +ke + + ++l+ +L ++ + L+kqle ++ + +++ lk ++k+l+++++++++ l+ FUN_001323-T1 540 LRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITELR 624 57899*********************************************************************99998766665 PP == domain 3 score: 0.4 bits; conditional E-value: 0.22 GAS 47 kelseieqenkrlkepLekaeeeveeLkkqle 78 k+l e+++ +l++ ++kae+++ +k l+ FUN_001323-T1 657 KHLGEYSKTHVQLSKYIQKAEQNISMAQKGLS 688 78888999999999999999999988888776 PP >> DUF7365 Coiled-coil region of unknown function (DUF7365) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.18 4.2e+02 78 100 .. 538 560 .. 513 561 .. 0.82 2 ? 7.1 5.4 0.0035 8.1 44 98 .. 570 624 .. 566 627 .. 0.93 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.18 DUF7365 78 eqvknLsedvrelkkdikeikkk 100 e + nL e+++ +k+++ ei+k+ FUN_001323-T1 538 EELRNLHEELKSVKDQLFEITKE 560 7789999*******999999875 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0035 DUF7365 44 kLevkveelekviksharRLdkhdeqqkallalveqvknLsedvrelkkdikeik 98 +Le + + +++i++ ++ L++ + q + l qvk+L++++++ ++ i e++ FUN_001323-T1 570 ELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITELR 624 68999999999***********************************999999975 PP >> DUF2935 Domain of unknown function (DUF2935) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.059 1.4e+02 74 108 .. 422 456 .. 404 458 .. 0.92 2 ? 4.8 2.6 0.024 55 37 92 .. 569 624 .. 465 633 .. 0.88 3 ? -3.5 0.0 9 2.1e+04 39 62 .. 655 678 .. 651 691 .. 0.57 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.059 DUF2935 74 aleltkelinFkkelleeilsckilsiiypllldH 108 +++ +++l+ Fk++ll+ + + +++pl l+H FUN_001323-T1 422 FMQMLTDLKSFKTQLLKLKRELQEAEVVSPLTLSH 456 5778899**************************99 PP == domain 2 score: 4.8 bits; conditional E-value: 0.024 DUF2935 37 defkkeFeellaeavelsgglrtnpelepalsklneealeltkelinFkkelleei 92 +e+++e+++ +++ + l++ l+ +++++ +++ l +++ +lt+++ + +++++e FUN_001323-T1 569 EELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITELR 624 566777788888888888888******************************99875 PP == domain 3 score: -3.5 bits; conditional E-value: 9 DUF2935 39 fkkeFeellaeavelsgglrtnpe 62 f k++ e+ ++ v+ls++++ +++ FUN_001323-T1 655 FVKHLGEYSKTHVQLSKYIQKAEQ 678 555555555555555555543333 PP >> Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.2 6.4 1.5e+04 76 93 .. 429 446 .. 423 448 .. 0.56 2 ? 13.3 8.0 4.5e-05 0.1 23 100 .. 546 623 .. 515 626 .. 0.92 3 ? -1.7 0.1 2.1 4.9e+03 14 49 .. 643 677 .. 639 690 .. 0.47 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 6.4 Seryl_tRNA_N 76 vkelkeelkaleeelkel 93 k+ k++l +l+ el+e+ FUN_001323-T1 429 LKSFKTQLLKLKRELQEA 446 455555555556555555 PP == domain 2 score: 13.3 bits; conditional E-value: 4.5e-05 Seryl_tRNA_N 23 edkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevkelkeelkaleeelkeleaelekl 100 e k+ d+l+e+ ++r +++++ eel +e + + +I + k+ e ++ +e++ lk ++k l ++ ++ ++++++l FUN_001323-T1 546 ELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITEL 623 5667789***************************************************************99998875 PP == domain 3 score: -1.7 bits; conditional E-value: 2.1 Seryl_tRNA_N 14 vkeklkkRgedkadvdelleldekrrelqveleelq 49 vk+ +++R +a v++l e + +l + ++++ FUN_001323-T1 643 VKADIRNRL-RDAFVKHLGEYSKTHVQLSKYIQKAE 677 444454443.33444444444444444433333332 PP >> REST_helical Helical region in REST corepressor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.1 0.00061 1.4 2 44 .. 400 445 .. 399 453 .. 0.89 2 ? -0.5 0.0 0.89 2.1e+03 28 51 .. 462 485 .. 447 489 .. 0.82 3 ? 0.2 0.1 0.55 1.3e+03 24 42 .. 536 554 .. 528 577 .. 0.84 4 ? -1.0 5.6 1.2 2.8e+03 33 57 .. 597 621 .. 552 624 .. 0.85 5 ? 1.6 0.1 0.2 4.6e+02 36 56 .. 667 687 .. 642 690 .. 0.85 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00061 REST_helical 2 kPPkGmyln..qedlvavsas.pdqgdallrqlDselvsLKrqvQn 44 +PPk m ++ + d+v + + +q + l+++ ++l +LKr Q+ FUN_001323-T1 400 RPPKQMTVTdgESDIVEMDEAgFMQMLTDLKSFKTQLLKLKRELQE 445 8*******84458999998877999999***************997 PP == domain 2 score: -0.5 bits; conditional E-value: 0.89 REST_helical 28 lrqlDselvsLKrqvQnnKqviSa 51 + +l se+ sL r+ + K+++S FUN_001323-T1 462 TVSLGSEFDSLERKTPQRKRMLSR 485 567889**************9996 PP == domain 3 score: 0.2 bits; conditional E-value: 0.55 REST_helical 24 gdallrqlDselvsLKrqv 42 +++ lr+l +el s+K q FUN_001323-T1 536 ASEELRNLHEELKSVKDQL 554 456799**********996 PP == domain 4 score: -1.0 bits; conditional E-value: 1.2 REST_helical 33 selvsLKrqvQnnKqviSalkekle 57 e+ LKrqv++ +i +++++++ FUN_001323-T1 597 DEMAYLKRQVKSLTNQIEQQQQRIT 621 5788899999999999999998876 PP == domain 5 score: 1.6 bits; conditional E-value: 0.2 REST_helical 36 vsLKrqvQnnKqviSalkekl 56 v+L + +Q++ q+iS+ ++ l FUN_001323-T1 667 VQLSKYIQKAEQNISMAQKGL 687 789999*********998866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (747 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2370 (0.0927775); expected 510.9 (0.02) Passed bias filter: 740 (0.0289685); expected 510.9 (0.02) Passed Vit filter: 111 (0.00434527); expected 25.5 (0.001) Passed Fwd filter: 45 (0.0017616); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.50u 0.38s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 6981.60 // Query: FUN_001323-T2 [L=725] Description: FUN_001323 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0096 16.4 9.9 0.0096 16.4 6.1 2.8 2 CCDC24 Coiled-coil domain-containing protein 24 family ------ inclusion threshold ------ 0.028 15.0 5.5 0.13 12.9 5.5 2.2 1 Prefoldin_3 Prefoldin subunit 0.17 13.6 12.2 4.7 8.9 2.8 4.6 4 DUF5320 Family of unknown function (DUF5320) 0.2 12.0 10.4 0.068 13.5 4.7 2.8 2 SKA2 Spindle and kinetochore-associated protein 2 0.37 11.5 18.6 0.15 12.8 8.5 3.4 3 Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 1 10.4 4.2 53 4.9 2.6 3.0 2 DUF2935 Domain of unknown function (DUF2935) 1 9.0 8.6 4.3 7.0 8.6 2.0 1 TMEM120A-B TMEM120A/B 1.1 9.6 15.8 0.036 14.5 6.9 3.0 3 WWC1 WWC1-like, helical hairpin 2.3 8.0 18.1 0.7 9.7 13.5 2.3 2 GAS Growth-arrest specific micro-tubule binding 2.5 8.8 9.7 7.8 7.2 5.4 3.2 2 DUF7365 Coiled-coil region of unknown function (DUF7365 3.3 8.4 13.2 1.4 9.7 0.1 4.4 4 REST_helical Helical region in REST corepressor 8 7.0 19.3 0.18 12.3 11.1 2.4 3 SYCE1 Synaptonemal complex central element protein 1 8 7.5 12.4 15 6.6 1.2 3.7 3 DUF4140 N-terminal domain of unknown function (DUF4140) Domain annotation for each model (and alignments): >> CCDC24 Coiled-coil domain-containing protein 24 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 6.1 4.9e-06 0.0096 101 181 .. 518 599 .. 470 605 .. 0.79 2 ? 2.1 0.2 0.11 2.3e+02 155 189 .. 597 631 .. 596 634 .. 0.86 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 4.9e-06 CCDC24 101 eeeespssrPeteisqlssassnsssdrelkeikdkL.NvsdidqvaehLRelLeeEceaLerdIeyLqecleeelslakev 181 e++ s +r +t+ ++ ++++ ++++elk++kd+L +++ + Re Le E ++ ++ I +Lq++le++++++ e+ FUN_001323-T2 518 ERTDSTNQRNQTPEPNAGASEELRNLHEELKSVKDQLfEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQDEM 599 44555556666666666677999*************95566666677788***************************99887 PP == domain 2 score: 2.1 bits; conditional E-value: 0.11 CCDC24 155 eEceaLerdIeyLqecleeelslakevseaakePs 189 E++ L+r+++ L +++e++ ++ +e+ ++ Ps FUN_001323-T2 597 DEMAYLKRQVKSLTNQIEQQQQRITELRFRSSSPS 631 7999****************999998886666666 PP >> Prefoldin_3 Prefoldin subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 5.5 6.4e-05 0.13 16 98 .. 535 620 .. 521 621 .. 0.83 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 6.4e-05 Prefoldin_3 16 glkeeiealkeeddatkedllriarefegslvnekEikeilGekqgvtrs.kqQvvdlis..rRiDYVkqniktlekrleaaenkl 98 g ee+++l+ee ++ k++l +i++e ++ l+ ++E+++ l +k+ + r ++Q+ + + + Y k+ +k+l+ ++e++++++ FUN_001323-T2 535 GASEELRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMlQKQLESQSDsqDEMAYLKRQVKSLTNQIEQQQQRI 620 6789*********************************99888877666651566666554114688**************999875 PP >> DUF5320 Family of unknown function (DUF5320) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 2.8 5.4e+03 64 90 .. 80 106 .. 24 113 .. 0.55 2 ? 0.9 0.0 0.75 1.5e+03 15 53 .. 138 178 .. 134 197 .. 0.64 3 ? 6.1 0.0 0.019 36 47 98 .. 507 556 .. 481 563 .. 0.60 4 ? 8.9 2.8 0.0024 4.7 64 99 .] 588 623 .. 574 623 .. 0.87 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 2.8 DUF5320 64 aaaqeaskeeekelLkeqaelLeeeLe 90 + ++++ke+ l ++q+++L +L FUN_001323-T2 80 SKDDNVTKEQHSILSESQINMLSFNLW 106 334444444444444555555555555 PP == domain 2 score: 0.9 bits; conditional E-value: 0.75 DUF5320 15 mtGrglGyCagaaapgyansaglGr.Grg.grgfgRgfgrr 53 m+ + +G+C +++++ +++ + r G +++ f r+ FUN_001323-T2 138 MSSQTFGTCDDEQTSRFKTPYSRQRrGSKtFASRQKSFTRK 178 788899****9999988888555553444333444444443 PP == domain 3 score: 6.1 bits; conditional E-value: 0.019 DUF5320 47 gRgfgrrrlaggaglaaaaaqeaskeeekelLkeqaelLeeeLeaikkrLee 98 g gfg++ ++ ++ ++q++++ e ++ e+ ++L eeL+++k++L e FUN_001323-T2 507 GDGFGNSKNVTERTDS--TNQRNQTPEPNAGASEELRNLHEELKSVKDQLFE 556 4455554444444443..4555555555555666666777777777766644 PP == domain 4 score: 8.9 bits; conditional E-value: 0.0024 DUF5320 64 aaaqeaskeeekelLkeqaelLeeeLeaikkrLeel 99 + ++++++++e ++Lk+q++ L +++e+ ++r+ el FUN_001323-T2 588 QLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITEL 623 4568999**************************986 PP >> SKA2 Spindle and kinetochore-associated protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 0.55 1.1e+03 39 63 .. 421 445 .. 413 450 .. 0.79 2 ? 13.5 4.7 3.5e-05 0.068 38 105 .. 538 601 .. 523 606 .. 0.73 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.55 SKA2 39 npvkLlerlkklkeelqaLkeqcee 63 +++l++lk k++l +Lk++ +e FUN_001323-T2 421 GFMQMLTDLKSFKTQLLKLKRELQE 445 4789999999999999999998887 PP == domain 2 score: 13.5 bits; conditional E-value: 3.5e-05 SKA2 38 enpvkLlerlkklkeelqaLkeqceellaekqelvdkirttLvsnrellqqLqasaelpplteeeqea 105 e++++L+e+lk +k++l ++ ++ + +l +++e +++ L s+ +++++Lq+++e ++ +++e ++ FUN_001323-T2 538 EELRNLHEELKSVKDQLFEITKERDSVLIAREE----LEHELDSKNHTIRMLQKQLESQSDSQDEMAY 601 556666666666666666666666666666655....5789999****************99999776 PP >> Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.2 7.3 1.4e+04 76 93 .. 429 446 .. 423 448 .. 0.56 2 ? 12.8 8.5 7.6e-05 0.15 23 100 .. 546 623 .. 514 626 .. 0.92 3 ? 4.6 0.2 0.026 52 12 64 .. 641 693 .. 639 702 .. 0.84 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 7.3 Seryl_tRNA_N 76 vkelkeelkaleeelkel 93 k+ k++l +l+ el+e+ FUN_001323-T2 429 LKSFKTQLLKLKRELQEA 446 455555555566555555 PP == domain 2 score: 12.8 bits; conditional E-value: 7.6e-05 Seryl_tRNA_N 23 edkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevkelkeelkaleeelkeleaelekl 100 e k+ d+l+e+ ++r +++++ eel +e + + +I + k+ e ++ +e++ lk ++k l ++ ++ ++++++l FUN_001323-T2 546 ELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITEL 623 5667789***************************************************************99998875 PP == domain 3 score: 4.6 bits; conditional E-value: 0.026 Seryl_tRNA_N 12 eavkeklkkRgedkadvdelleldekrrelqvele.elqaerNelskeIgkakk 64 e+vk+ +++R +a v++l e + r l+ + + qa +N+lsk I+ + + FUN_001323-T2 641 ETVKADIRNRL-RDAFVKHLGEYSKTNRDLRPKDQiPSQASKNSLSKRIQMIGD 693 78999999996.77999************998776368***********98755 PP >> DUF2935 Domain of unknown function (DUF2935) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.067 1.3e+02 74 108 .. 422 456 .. 404 458 .. 0.92 2 ? 4.9 2.6 0.027 53 37 92 .. 569 624 .. 465 633 .. 0.88 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.067 DUF2935 74 aleltkelinFkkelleeilsckilsiiypllldH 108 +++ +++l+ Fk++ll+ + + +++pl l+H FUN_001323-T2 422 FMQMLTDLKSFKTQLLKLKRELQEAEVVSPLTLSH 456 5778899**************************99 PP == domain 2 score: 4.9 bits; conditional E-value: 0.027 DUF2935 37 defkkeFeellaeavelsgglrtnpelepalsklneealeltkelinFkkelleei 92 +e+++e+++ +++ + l++ l+ +++++ +++ l +++ +lt+++ + +++++e FUN_001323-T2 569 EELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITELR 624 566777788888888888888******************************99875 PP >> TMEM120A-B TMEM120A/B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 8.6 0.0022 4.3 2 84 .. 538 622 .. 536 631 .. 0.74 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0022 TMEM120A-B 2 eeweelekefkeleetakeykekleelsklqskcskeiskqkkrlkelksslkklkkkv..keeekeaveeleeelkerkaqlke 84 ee+++l++e k+++++ e++++ +++ +++++++e++++++ ++ l+++l++ + ++ + k++v++l++++++++++++e FUN_001323-T2 538 EELRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQdeMAYLKRQVKSLTNQIEQQQQRITE 622 6778888888888888888888888888888888888888888888888888887766422333456777777777777777665 PP >> WWC1 WWC1-like, helical hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 4.9 9.7e+03 73 90 .. 430 447 .. 424 454 .. 0.61 2 ? 14.5 6.9 1.8e-05 0.036 61 134 .. 522 595 .. 518 596 .. 0.95 3 ? -1.1 0.2 1.2 2.3e+03 17 33 .. 603 619 .. 596 628 .. 0.51 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 4.9 WWC1 73 ekleeekkrLeedlqsar 90 ++ + + +L+++lq+a FUN_001323-T2 430 KSFKTQLLKLKRELQEAE 447 444555556666666664 PP == domain 2 score: 14.5 bits; conditional E-value: 1.8e-05 WWC1 61 sispkkrseeelekleeekkrLeedlqsarelsskaiadRlklqeekkkLlqqLeeatrlttlLesqLkslSas 134 s +++++++e + ee ++L e+l+s+++ + ++R ++ +++L ++L + ++ +L++qL s S s FUN_001323-T2 522 STNQRNQTPEPNAGASEELRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDS 595 567899999999999*********************************************************98 PP == domain 3 score: -1.1 bits; conditional E-value: 1.2 WWC1 17 kkrvqklqqqLakleee 33 k++v++l +q+++ +++ FUN_001323-T2 603 KRQVKSLTNQIEQQQQR 619 44444444444444444 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 0.79 1.6e+03 86 105 .. 428 447 .. 416 498 .. 0.71 2 ? 9.7 13.5 0.00035 0.7 28 112 .. 540 624 .. 537 629 .. 0.91 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.79 GAS 86 slknlkarlkelekelkelk 105 +lk+ k++l +l++el+e + FUN_001323-T2 428 DLKSFKTQLLKLKRELQEAE 447 45566666666666665554 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00035 GAS 28 ikslKeeiaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknlkarlkelekelkelkwehevle 112 ++l ee++ +k + e +ke + + ++l+ +L ++ + L+kqle ++ + +++ lk ++k+l+++++++++ l+ FUN_001323-T2 540 LRNLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITELR 624 57899*********************************************************************99998766665 PP >> DUF7365 Coiled-coil region of unknown function (DUF7365) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.1 0.2 4e+02 78 100 .. 538 560 .. 513 561 .. 0.82 2 ? 7.2 5.4 0.004 7.8 44 98 .. 570 624 .. 566 627 .. 0.93 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.2 DUF7365 78 eqvknLsedvrelkkdikeikkk 100 e + nL e+++ +k+++ ei+k+ FUN_001323-T2 538 EELRNLHEELKSVKDQLFEITKE 560 7789999*******999999875 PP == domain 2 score: 7.2 bits; conditional E-value: 0.004 DUF7365 44 kLevkveelekviksharRLdkhdeqqkallalveqvknLsedvrelkkdikeik 98 +Le + + +++i++ ++ L++ + q + l qvk+L++++++ ++ i e++ FUN_001323-T2 570 ELEHELDSKNHTIRMLQKQLESQSDSQDEMAYLKRQVKSLTNQIEQQQQRITELR 624 68999999999***********************************999999975 PP >> REST_helical Helical region in REST corepressor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.1 0.0007 1.4 2 44 .. 400 445 .. 399 453 .. 0.89 2 ? -0.5 0.0 1.1 2.1e+03 28 51 .. 462 485 .. 448 489 .. 0.82 3 ? -0.2 0.0 0.86 1.7e+03 24 41 .. 536 553 .. 528 558 .. 0.84 4 ? -1.0 5.7 1.5 3e+03 33 57 .. 597 621 .. 552 624 .. 0.85 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.0007 REST_helical 2 kPPkGmyln..qedlvavsas.pdqgdallrqlDselvsLKrqvQn 44 +PPk m ++ + d+v + + +q + l+++ ++l +LKr Q+ FUN_001323-T2 400 RPPKQMTVTdgESDIVEMDEAgFMQMLTDLKSFKTQLLKLKRELQE 445 8*******84458999998877999999***************997 PP == domain 2 score: -0.5 bits; conditional E-value: 1.1 REST_helical 28 lrqlDselvsLKrqvQnnKqviSa 51 + +l se+ sL r+ + K+++S FUN_001323-T2 462 TVSLGSEFDSLERKTPQRKRMLSR 485 567889**************9996 PP == domain 3 score: -0.2 bits; conditional E-value: 0.86 REST_helical 24 gdallrqlDselvsLKrq 41 +++ lr+l +el s+K q FUN_001323-T2 536 ASEELRNLHEELKSVKDQ 553 55679***********99 PP == domain 4 score: -1.0 bits; conditional E-value: 1.5 REST_helical 33 selvsLKrqvQnnKqviSalkekle 57 e+ LKrqv++ +i +++++++ FUN_001323-T2 597 DEMAYLKRQVKSLTNQIEQQQQRIT 621 5788899999999999999998876 PP >> SYCE1 Synaptonemal complex central element protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.2 3 5.9e+03 99 129 .. 73 103 .. 45 124 .. 0.53 2 ? -2.9 0.0 4.3 8.5e+03 65 76 .. 436 447 .. 422 484 .. 0.59 3 ? 12.3 11.1 9e-05 0.18 23 110 .. 542 625 .. 539 630 .. 0.82 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 3 SYCE1 99 qeeklkqrkqrlkfeeqledlmeqhkdlwef 129 qe+ l +k + +eq+ l e + ++ +f FUN_001323-T2 73 QEALLPCSKDDNVTKEQHSILSESQINMLSF 103 4455555555555555555555555544444 PP == domain 2 score: -2.9 bits; conditional E-value: 4.3 SYCE1 65 iLqlhcqekese 76 +L+l+ + +e e FUN_001323-T2 436 LLKLKRELQEAE 447 333333333333 PP == domain 3 score: 12.3 bits; conditional E-value: 9e-05 SYCE1 23 kleeeLgEaqalkealkkEldslnaekvhLeevlnkKqealriLqlhcqekeseaqrkhelneeckeriealtsqiqeeklkqrkqrl 110 +l eeL+ ++ + kE ds+ + +Le l K+ ++r+Lq + + + + q e+ k +++ lt qi++++++ ++r FUN_001323-T2 542 NLHEELKSVKDQLFEITKERDSVLIAREELEHELDSKNHTIRMLQKQLESQS-DSQD--EM-AYLKRQVKSLTNQIEQQQQRITELRF 625 5789******9999*******************************9987665.4444..44.455666999*****998776666654 PP >> DUF4140 N-terminal domain of unknown function (DUF4140) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 2 3.8e+03 66 86 .. 427 447 .. 396 448 .. 0.70 2 ? 6.6 1.2 0.0077 15 65 92 .. 528 564 .. 509 572 .. 0.73 3 ? 3.7 3.5 0.059 1.2e+02 48 92 .. 581 623 .. 566 628 .. 0.66 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2 DUF4140 66 eelkelreeieeleaelaale 86 ++lk+ + ++ +l++el+++e FUN_001323-T2 427 TDLKSFKTQLLKLKRELQEAE 447 568888899999999998875 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0077 DUF4140 65 e.........eelkelreeieeleaelaaledelaal 92 + eel+ l ee+++++++l ++++e++++ FUN_001323-T2 528 QtpepnagasEELRNLHEELKSVKDQLFEITKERDSV 564 122234556567*******************999875 PP == domain 3 score: 3.7 bits; conditional E-value: 0.059 DUF4140 48 tildvsvervprreaeeeeelkelreeieeleaelaaledelaal 92 ti ++ + + ++++++e ++ l++++++l++++++ +++++ l FUN_001323-T2 581 TIRMLQKQLESQSDSQDE--MAYLKRQVKSLTNQIEQQQQRITEL 623 555555555555555555..7777777777777777777766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (725 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2227 (0.0871795); expected 510.9 (0.02) Passed bias filter: 721 (0.0282247); expected 510.9 (0.02) Passed Vit filter: 113 (0.00442357); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.48u 0.37s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 6946.45 // Query: FUN_001324-T1 [L=159] Description: FUN_001324 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-27 96.7 0.1 1.9e-27 96.1 0.1 1.3 1 DUF4562 Domain of unknown function (DUF4562) Domain annotation for each model (and alignments): >> DUF4562 Domain of unknown function (DUF4562) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.1 0.1 7.4e-32 1.9e-27 27 110 .. 1 81 [. 1 86 [. 0.94 Alignments for each domain: == domain 1 score: 96.1 bits; conditional E-value: 7.4e-32 DUF4562 27 palektsdleYLwRpaskrslaakekheyvgeiGWgipelsfinksrlesgfqikrgelrqaaedkvtHryqnPWqpkpsildq 110 +++e+ts+l+YLwRp + ++++ k+ +vgeiGWg++ ++ + + l+sg qik ge+rq++ed++tH yqnPW+p p+ + FUN_001324-T1 1 MSPEGTSNLNYLWRPSR-GCAHPVAKSAKVGEIGWGLQFYT--DYQLLRSGHQIKLGEFRQSTEDRHTHLYQNPWYPGPNDEKV 81 589************99.9********************99..99**********************************87655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (159 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 641 (0.025093); expected 510.9 (0.02) Passed bias filter: 354 (0.0138579); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1639.33 // Query: FUN_001325-T1 [L=284] Description: FUN_001325 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-89 299.2 9.2 4.3e-89 299.0 9.2 1.0 1 Porin_3 Eukaryotic porin Domain annotation for each model (and alignments): >> Porin_3 Eukaryotic porin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 299.0 9.2 1.7e-93 4.3e-89 2 271 .] 5 277 .. 4 277 .. 0.99 Alignments for each domain: == domain 1 score: 299.0 bits; conditional E-value: 1.7e-93 Porin_3 2 PgtyedlgkeakdllnkdYhfegakldvttksslgvafqvsgskslgsgkvsydleakykd..kgltltlkgdtdndlsteaevneqlapglktkl 95 P++y+dlgke +d++ k+Y f+++kldv+tks++gv+f +sgs++ +sgkv ++le+kyk+ +g tl+ k++tdn + t++ v++qla+glk+++ FUN_001325-T1 5 PPKYDDLGKESRDVFGKGYGFGAVKLDVKTKSKNGVEFITSGSSNNESGKVLGSLETKYKYtdYGVTLSDKWTTDNVITTNISVEDQLAKGLKMEF 100 9*********************************************************************************************** PP Porin_3 96 stqlvpekgkksakleleykgddftaslkvgl.lkgpvvvasllqgvtglalGaevvydtasgkltkynaalgyaardliaslqlenngdaltaSy 190 +++++p++gkksak++ yk+d+f+ +++v++ ++gp v+as+++g++g+++G++++ydta++kl ++n+ +gy +d++ + ++ n+++ +t+++ FUN_001325-T1 101 DASFAPNTGKKSAKIKSAYKQDYFHGTADVDFdFAGPAVQASAVVGYEGWVAGYQAAYDTAKSKLIANNFSFGYRSSDFNIHSSV-NDASRFTGAI 195 ********************************999*************************************************9.79******** PP Porin_3 191 yhkvseklevgaeltlnfssnestvtiGakydldksttvkakvnsngkvglllekkLrpgvtltlsaevDhkkan.kahkfG 271 yhk+s++le++a+l+++++s+ +++++G+kyd+d +t+ +akvn+++ vgl++++ Lr+gv++tls ++D+k++n + hk+G FUN_001325-T1 196 YHKISSNLETAAQLNWASGSSSTSFQVGCKYDVDADTSIRAKVNNTSLVGLAYTQCLREGVKVTLSSQIDTKNLNqGGHKIG 277 *********************************************************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (284 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 623 (0.0243883); expected 510.9 (0.02) Passed bias filter: 388 (0.0151889); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2861.23 // Query: FUN_001326-T1 [L=140] Description: FUN_001326 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-27 93.8 0.0 6.9e-27 93.3 0.0 1.3 1 Abhydro_lipase Partial alpha/beta-hydrolase lipase region 0.00083 19.6 0.5 0.0014 18.8 0.3 1.4 2 Abhydrolase_1 alpha/beta hydrolase fold Domain annotation for each model (and alignments): >> Abhydro_lipase Partial alpha/beta-hydrolase lipase region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.3 0.0 5.4e-31 6.9e-27 1 63 [] 34 96 .. 34 96 .. 0.98 Alignments for each domain: == domain 1 score: 93.3 bits; conditional E-value: 5.4e-31 Abhydro_lipase 1 vseiikkyGypveeheVtTeDGYiLtlhRipagrkksekkekkpvvllqHGLlasSeswvtnl 63 v+eii++ Gyp+ee++VtT+DGYiLt++Rip gr+++++ ++kpv+l qHGLlasS++wv+nl FUN_001326-T1 34 VTEIINYNGYPAEEYTVTTDDGYILTIQRIPGGRQETPSAGPKPVILVQHGLLASSSNWVVNL 96 689*********************************************************995 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 0.69 8.8e+03 167 188 .. 41 62 .. 37 66 .. 0.76 2 ! 18.8 0.3 1.1e-07 0.0014 1 41 [. 77 123 .. 77 137 .. 0.81 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 0.69 Abhydrolase_1 167 edlalakslvtgallfletwst 188 ++++ + ++vt+++++++t++ FUN_001326-T1 41 NGYPAEEYTVTTDDGYILTIQR 62 5677788889999999888875 PP == domain 2 score: 18.8 bits; conditional E-value: 1.1e-07 Abhydrolase_1 1 ppvlllHGlpgssdlwrk......lapaLakdgfrvialDlrGfGkS 41 p++l+ HGl++ss +w ++ La++gf+v++ ++rG+ + FUN_001326-T1 77 PVILVQHGLLASSSNWVVnlpnesFGFILADKGFDVWLGNVRGNTYG 123 89*************99964444433336777***********9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (140 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 509 (0.0199256); expected 510.9 (0.02) Passed bias filter: 443 (0.0173419); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1414.25 // Query: FUN_001327-T1 [L=266] Description: FUN_001327 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-15 56.3 0.1 6.3e-15 56.0 0.1 1.1 1 Abhydrolase_1 alpha/beta hydrolase fold 1.1e-05 25.4 0.0 0.11 12.3 0.0 2.2 2 Hydrolase_4 Serine aminopeptidase, S33 Domain annotation for each model (and alignments): >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.0 0.1 4.9e-19 6.3e-15 53 244 .. 4 236 .. 1 237 [. 0.89 Alignments for each domain: == domain 1 score: 56.0 bits; conditional E-value: 4.9e-19 Abhydrolase_1 53 ddlaedlekildalglekvnlvGhSlGGlialayaaky...pervkalvllga......lspaaeldeaa...rfilasfpgffdgfvadfarnrl 136 dl ++++il+++g++ +++ GhS+G+li +a ++++ +++ka+ +g+ ++++ +++ ++ +l+ + g +d ++d+ ++l FUN_001327-T1 4 YDLPTIVNFILNKTGQPSLYYAGHSQGTLIPFAELSRNkelAQKIKAVFAMGPvaylnhMESPLKYIADLtpeVEFLFEVFGVRDFLPSDDIIHWL 99 678999***************************************************996666666655411145667788999************ PP Abhydrolase_1 137 grlvakelallllrlrllkal...pelskrfpsedlalakslvtgallfletwstelrakllgrlde.........................ptlv 204 +++v+k++ l +l++++ + + + +++ + +++a++++ +++++++++++ +++k+++ +d p+ + FUN_001327-T1 100 ATYVCKPSDLKELCSNIIFIIcgfDKPQLNMTRIPVYIAHTPAGTSVKNMVHFAQMYKYKKFQMFDYgspeknkqhygidtppqynasafdvPVAL 195 *****************9999***99999999999*******************************9***************************** PP Abhydrolase_1 205 iwgeqDplvppqaleklaqlfpnar.evvipdagHfafleg 244 +wg++D+l +pq l +l+p++ + + + H++f++g FUN_001327-T1 196 YWGGNDWLADPQDVQTLMKLLPKKMpDKYLAAWQHLDFIWG 236 ***********888888889888541455566777777775 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.0 0.0 2.2e-05 0.28 61 122 .. 5 67 .. 3 90 .. 0.83 2 ! 12.3 0.0 8.7e-06 0.11 185 219 .. 185 219 .. 182 231 .. 0.85 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 2.2e-05 Hydrolase_4 61 DlaafvekikeehpglplfllGhSmGGaiallylleypd...kvkglilsaPalkikekvappll 122 Dl ++v++i ++ + l+ GhS G +i ++ l ++++ k+k++ ++P+ ++++ + l FUN_001327-T1 5 DLPTIVNFILNKTGQPSLYYAGHSQGTLIPFAELSRNKElaqKIKAVFAMGPVAYLNHM--ESPL 67 899999****999999******************7777766699999999**9998864..3333 PP == domain 2 score: 12.3 bits; conditional E-value: 8.7e-06 Hydrolase_4 185 raekitvPllllhGgaDkvvdpagsrelyeragsk 219 +a+++ vP+ l+ Gg+D++ dp++ + l++ +++k FUN_001327-T1 185 NASAFDVPVALYWGGNDWLADPQDVQTLMKLLPKK 219 7899*************************999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (266 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 692 (0.0270894); expected 510.9 (0.02) Passed bias filter: 639 (0.0250147); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2656.26 // Query: FUN_001328-T1 [L=955] Description: FUN_001328 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-97 327.6 5.1 4e-96 323.1 2.9 2.5 2 SAPS SIT4 phosphatase-associated protein ------ inclusion threshold ------ 0.088 12.6 0.1 0.21 11.4 0.1 1.6 1 Phage_TTP_1 Phage tail tube protein Domain annotation for each model (and alignments): >> SAPS SIT4 phosphatase-associated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 0.29 3.8e+03 105 131 .. 39 68 .. 30 115 .. 0.57 2 ! 323.1 2.9 3.1e-100 4e-96 1 421 [. 128 505 .. 128 506 .. 0.97 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 0.29 SAPS 105 igpneLtrelvseeivekLlkimlkg...k 131 + +L +ei e+L++ +l++ + FUN_001328-T1 39 SQNRKLIDFFLRPEILEELVDLVLQQpdeS 68 444455666666666667777666553331 PP == domain 2 score: 323.1 bits; conditional E-value: 3.1e-100 SAPS 1 nenLldrkteelleFikkkenlvdkllkhidtsaimdlLlklistdkp.elrtgiiewlkeqkLieklidllspeededvqsnasdflkaiitisa 95 ++ L++rkt+ +le++k+ke++vd ++kh++tsa+mdlLl+li+ ++ +lr++ +ewl++qkLie+l++l++pe d+d+ sna+++l+++i++s+ FUN_001328-T1 128 MGVLISRKTSLMLEYLKSKEDFVDLIVKHLGTSAVMDLLLRLITSVESpQLRQDLLEWLNNQKLIESLVSLIDPEVDDDRSSNAAQSLCDVIRLSR 223 5689***************************************988888*********************************************** PP SAPS 96 naalqlqssigpneLtrelvseeivekLlkimlkg...ksgsalvngvgiiielirknnsdydsvqllyttleehppsdrdpiylgellrlfsekl 188 ++++qlq++ ++++++ + +e+v++Ll++ml + + + alvng++++++l++ ++ + ++++ +++ + e+ + + +l +++++l FUN_001328-T1 224 DHMSQLQENADQDPVLDAVQRRETVSELLDHMLRDaqlHPDVALVNGISVLLTLLEVRKGSGEGEEPMTALDAERLAQGVSA-----TLAALTPRL 314 *********************************998888899************************9998888888888887.....********* PP SAPS 189 kdfaklLlekkkkeslkttlgeeiepLGfeRlkiveLiaeLLhcsnmsllnekkgekivkerdeereklkeddesseepaaeeteeklrnpvvGDl 284 kdf++lL +++ ++++ tt+g++ +pLG++Rl+ +Lia +L +++ +++ e FUN_001328-T1 315 KDFHQLLVDPPPMKPMLTTVGTLDPPLGNARLQASKLIAAILATNSDTINTE-------------------------------------------- 366 ****************************************************............................................ PP SAPS 285 lkikLvdlkiiktiLdlffkYpWnNfLHnvVfdivqqilngpmd...ksynsflvkdLfekakltqrilegqkesdefqkekgirlGymGhltlIA 377 L++l++++ +++lffkY WnNfLH++V+++v ++ln+p++ + +++lv Lf++++++qril+ +++ + + ++ r+GymGhlt++A FUN_001328-T1 367 ----LANLGTLQVLWELFFKYSWNNFLHTQVEKCVTTVLNNPPTeedGELSTPLVDVLFKDCQIIQRILQEWDDLELETGPGNKRKGYMGHLTNVA 458 ....**************************************99676778999***********************999999************** PP SAPS 378 eevvkfsekykeelisseilekl...eneeWeeyveetLeetrekyn 421 ++vv+ +ek+k+++ + i ++l +e+W+++v+ +L++++++++ FUN_001328-T1 459 NNVVQSVEKGKNKTTLEAIFNDLpekIRERWNSFVSGKLTDVNKQNM 505 ************************9889***************9885 PP >> Phage_TTP_1 Phage tail tube protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 1.6e-05 0.21 59 104 .. 457 502 .. 453 525 .. 0.79 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 1.6e-05 Phage_TTP_1 59 ygnnkvkdvevgksapqvaltvndLpfdikqkllGkvsdgkgGyvl 104 +nn v+ ve+gk++++++ +ndLp +i++ +vs + + + FUN_001328-T1 457 VANNVVQSVEKGKNKTTLEAIFNDLPEKIRERWNSFVSGKLTDVNK 502 68***************************99877777665555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (955 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1022 (0.0400078); expected 510.9 (0.02) Passed bias filter: 665 (0.0260325); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.43u 0.37s 00:00:00.80 Elapsed: 00:00:00.41 # Mc/sec: 9485.74 // Query: FUN_001329-T1 [L=100] Description: FUN_001329 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 887 (0.034723); expected 510.9 (0.02) Passed bias filter: 552 (0.0216089); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1015.93 // Query: FUN_001330-T1 [L=521] Description: FUN_001330 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-32 113.0 0.1 3.8e-32 111.8 0.1 1.6 1 Vanin_C Vanin C-terminal domain 5.6e-19 69.0 0.0 9e-19 68.3 0.0 1.2 1 CN_hydrolase Carbon-nitrogen hydrolase Domain annotation for each model (and alignments): >> Vanin_C Vanin C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 111.8 0.1 3e-36 3.8e-32 6 164 .. 343 491 .. 339 493 .. 0.90 Alignments for each domain: == domain 1 score: 111.8 bits; conditional E-value: 3e-36 Vanin_C 6 dlnldefttveltkksngtatvCqg..dlcCdfeyelseedksserYrlvvfdGirtyegvdkagvqvCalvaCsneslssCgklvesasttFtsl 99 dl+ d f + el k ++t vC++ + cC+++y++se++++ e Y+l+vfdG++t+eg ++++++C+l++C++ s +sCg++v +a+t F+++ FUN_001330-T1 343 DLFGDLFLFKEL-VKAEDTLDVCYNgsETCCSLSYKMSEKRSD-EIYALGVFDGLHTLEG--QYYLRICTLIKCLGLSRDSCGQRVYDARTIFDHF 434 677889999999.8999******77678***********9888.*************999..9********************************* PP Vanin_C 100 kisgtfpktrlvfPstldssllplepsefeyseeeeseevkvallslskpesnLltfgiygrnfd 164 k++g++ +t +v+P+++++++ l +e+e + v++++ s++ ++ Llt++++gr +d FUN_001330-T1 435 KLQGHL-NTPYVYPQVVADNVTLLP-DEWENNM-----PVTHVQ-SKQRLTKGLLTAALLGRVYD 491 ******.99*******988887777.6666554.....567777.88899*************98 PP >> CN_hydrolase Carbon-nitrogen hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.3 0.0 7e-23 9e-19 17 171 .. 61 242 .. 45 253 .. 0.78 Alignments for each domain: == domain 1 score: 68.3 bits; conditional E-value: 7e-23 CN_hydrolase 17 nlqkalelieeAarkgadLivlPElfitgy.......................keeaefleaaeagdgetlaalaalarkngiaivigliere... 86 n++ +e + A ++++++iv+PE+++tg+ + + + a ++l++l+ la+++++++vi + + + FUN_001330-T1 61 NMDVYEEQMKIAEQQNVSIIVFPEYGLTGFgytrdsfkpfledipdpkkghwnGCGDTLVNA----STPILHRLSCLAKTYNMYLVINMGDIKvcn 152 555556666668889***************99987777666666666665555555555555....55********************88888888 PP CN_hydrolase 87 ........eggkl.yntavlldpdgklvgkyrKlhLfdeprpptfverelfep....gdglpvfdtplgkiGaaiCyeirfpellra.lalkgaei 168 +g++ ynt v++d++g+lv++y+K h f +e +++ + + f+tp+gk+G+ iC + f ++ + +++++ FUN_001330-T1 153 kgmdshcpSDGRYqYNTNVVFDNEGNLVARYHKQHPF-------LNEMKVVNRplepEY--ITFETPFGKFGTFICFDVLFHDPAVPlVTRDNIDH 239 89******999999*********************77.......333333333321144..788*****************999999555566665 PP CN_hydrolase 169 lin 171 +++ FUN_001330-T1 240 VVF 242 555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (521 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 912 (0.0357017); expected 510.9 (0.02) Passed bias filter: 803 (0.0314347); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 5229.13 // Query: FUN_001331-T1 [L=140] Description: FUN_001331 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (140 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 453 (0.0177334); expected 510.9 (0.02) Passed bias filter: 369 (0.0144451); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1430.41 // Query: FUN_001332-T1 [L=753] Description: FUN_001332 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-21 76.0 0.2 7.9e-21 74.8 0.2 1.7 1 TFR_dimer Transferrin receptor-like dimerisation domain 4.6e-20 72.6 0.0 1.3e-19 71.2 0.0 1.7 1 Peptidase_M28 Peptidase family M28 8.7e-12 45.5 0.0 4e-11 43.4 0.0 1.9 2 PA PA domain 0.002 18.6 0.0 0.0038 17.7 0.0 1.4 1 DUF7283 Family of unknown function (DUF7283) ------ inclusion threshold ------ 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 Peptidase_M20 Peptidase family M20/M25/M40 0.14 12.4 0.3 0.44 10.8 0.0 1.8 2 EMC3_TMCO1 Integral membrane protein EMC3/TMCO1-like Domain annotation for each model (and alignments): >> TFR_dimer Transferrin receptor-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.8 0.2 1.8e-24 7.9e-21 5 121 .] 642 751 .. 632 751 .. 0.87 Alignments for each domain: == domain 1 score: 74.8 bits; conditional E-value: 1.8e-24 TFR_dimer 5 plkkaiekfkkaaeefdkwakkweevveasgkessllavrevNdklmlferafldpeglpgrpwfkHvvfapglwtgyagatFPgirdaiea.... 96 l ka+++f+k ++ef++ + +++ + ++r vNd++m++e+af++ + + + +Hv+++p+l + y+g++FP + da+e FUN_001332-T1 642 ALFKAVDNFAKVSHEFEANKVTIN-----------TKDLRLVNDQMMQLEKAFIQTVEPNNPRQLRHVIYGPDLLNLYGGKYFPRLNDAVEIaiks 726 566666666666666666666655...........78899*****************999***************99**************88999 PP TFR_dimer 97 gdweeaqkqisivakaiekaaesLk 121 gdw++++k+is ++ i++aa+ Lk FUN_001332-T1 727 GDWQQVEKEISLLTFSINSAANVLK 751 **********************996 PP >> Peptidase_M28 Peptidase family M28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.2 0.0 3e-23 1.3e-19 1 174 [. 371 575 .. 371 581 .. 0.77 Alignments for each domain: == domain 1 score: 71.2 bits; conditional E-value: 3e-23 Peptidase_M28 1 Nviaklkgkae.devlllsAHlDsvgvgpGAtDnasgvaallelarvlaa...skqqpkrsvrflffdaEEagllGSkafak..skp.elkkirav 89 Nvi+k++g++e d+++l++ H D + GA D sg+a+l+el+r l + s+++p+r++++ +daEE +++GS +++ + + +++ +a+ FUN_001332-T1 371 NVIGKIRGTEEpDRYVLMGNHRDAWV--FGAADPTSGTAILMELSRGLGEllkSGWRPRRTIILCSWDAEEIFVVGSAEYVEenA-QiLQDRAVAY 463 9*********9999***********9..7******************999999999*************************9633.36******** PP Peptidase_M28 90 lnlDmigsggkallf................qsgpktsselekylkaaa..kpvgktlaedpfqergipgrsDhapfa.kagipaldl........ 158 ln+D++ +g+ + + ++ t ++ ++ + +++ + v+k + pf ++ + sD+++f g++++d FUN_001332-T1 464 LNMDVAVNGNFSINVdanpllqnlaisltkeI-RDPTVHNSQRSMYDVMveRDVSKHVNGSPFCDN-LSFGSDYVAFYhFIGVSCADWsyifggrg 557 **************988888888777766632.222222222222222200222222222555544.47778888887456788888899999988 PP Peptidase_M28 159 ..aetkfkeryHtpkDtl 174 ++yH+++Dt+ FUN_001332-T1 558 thGIRRSYPVYHSSHDTF 575 764445567899999987 PP >> PA PA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.4 0.0 9.5e-15 4e-11 1 92 [. 188 276 .. 188 277 .. 0.84 2 ? -1.4 0.0 0.9 3.8e+03 80 95 .] 307 322 .. 296 322 .. 0.80 Alignments for each domain: == domain 1 score: 43.4 bits; conditional E-value: 9.5e-15 PA 1 vtgplVaapndgceasdgssedf........dvkGkivLvqrGectfaeKvrnAqaaGAagviiynnveg.g.lgapteaggeeleadpitiPavg 86 v++++V +a+ g+++df +vk+kiv+v++G ++ Kv nA+ GA+g+iiy ++e+ + +g+ + + ++++++P +g FUN_001332-T1 188 VEAEIV-------YANFGREKDFeqlkgmgvSVKNKIVIVRQGRVFRGNKVSNAALLGASGAIIYTDPEEfApDGPLN------TFPKSWWLPDTG 270 578888.......777787788888899999**********************************9998764334444......45778******* PP PA 87 iskadg 92 i+++++ FUN_001332-T1 271 IQRGSA 276 *99875 PP == domain 2 score: -1.4 bits; conditional E-value: 0.9 PA 80 itiPavgiskadgeal 95 tiPa+ +s++d++++ FUN_001332-T1 307 PTIPAMAMSYGDAKEI 322 79**********9976 PP >> DUF7283 Family of unknown function (DUF7283) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 8.9e-07 0.0038 50 138 .. 649 736 .. 640 740 .. 0.88 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 8.9e-07 DUF7283 50 yeataeheldAdevrigprrvalrndggtahatlaygpvvpvaederLeavlrGeppesvf..dspaafaaaveearareeeewreaddeL 138 a+ +he++A++v+i+++ ++l nd+ + ++ +++v p + +L++v++G + + + + ++++ave a ++ ++w+++++e+ FUN_001332-T1 649 NFAKVSHEFEANKVTINTKDLRLVNDQMMQLEKAFIQTVEPNN-PRQLRHVIYGPDLLNLYggKYFPRLNDAVEIAIKS--GDWQQVEKEI 736 568999**************************99999999998.689**************665667889999998865..8999999887 PP >> Peptidase_M20 Peptidase family M20/M25/M40 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 4.4e-05 0.19 32 113 .. 398 624 .. 394 694 .. 0.60 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 4.4e-05 xxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx........ RF Peptidase_M20 32 Ghddhkggllaalea...lralkeeglkpkgtvkllfqpdEEggsgGakalie...gllekekvdavfglhigeptlle.gkigigvg........ 112 G++d ++g ++++e+ l +l ++g +p++t+ l+ + +EE+ G+ +++e ++l ++++ a++ + + + g+++i+v FUN_001332-T1 398 GAADPTSGTAILMELsrgLGELLKSGWRPRRTIILCSWDAEEIFVVGSAEYVEenaQIL-QDRAVAYLNMD-----VAVnGNFSINVDanpllqnl 487 666666666666665111568889999***************85589988888655444.33444434333.....33335555666666777777 PP ................................................................................................ RF Peptidase_M20 113 ................................................................................................ 112 FUN_001332-T1 488 aisltkeirdptvhnsqrsmydvmverdvskhvngspfcdnlsfgsdyvafyhfigvscadwsyifggrgthgirrsypvyhsshdtfywiktfid 583 555556666666666666666666666666666666666666666666666666666666666666555555555555555555555555555555 PP ........................................x RF Peptidase_M20 113 ........................................e 113 FUN_001332-T1 584 pefkthlavgkfaaifllelsespllpfntttyanllnskA 624 55555555555555555555555555555555555555542 PP >> EMC3_TMCO1 Integral membrane protein EMC3/TMCO1-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.0001 0.44 12 62 .. 25 73 .. 18 107 .. 0.63 2 ? -2.0 0.1 0.86 3.6e+03 34 60 .. 660 686 .. 614 696 .. 0.67 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0001 EMC3_TMCO1 12 llPivivillvailrgllsellqkllidkkkmekvkkrekelqkrarelqk 62 + +v++++ v+ ++g+++++++ +d k + ++ e+ +++r + FUN_001332-T1 25 TFSVVLLVVCVSFICGYFTNVIHRAIVDEKVQPET--DSVEMSRKRRLASD 73 466788999999*****************944433..33333333333333 PP == domain 2 score: -2.0 bits; conditional E-value: 0.86 EMC3_TMCO1 34 qkllidkkkmekvkkrekelqkrarel 60 +k++i+ k ++ v++++ +l+k + + FUN_001332-T1 660 NKVTINTKDLRLVNDQMMQLEKAFIQT 686 455666666666666666666666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (753 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 936 (0.0366412); expected 510.9 (0.02) Passed bias filter: 765 (0.0299472); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7150.21 // Query: FUN_001333-T1 [L=934] Description: FUN_001333 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-20 74.4 0.0 3.1e-20 72.9 0.0 1.9 2 DUF4537 Domain of unknown function (DUF4537) 4.2e-10 40.4 0.0 8.6e-10 39.4 0.0 1.6 1 VWA_3 von Willebrand factor type A domain 3.2e-05 24.7 0.0 6.9e-05 23.6 0.0 1.6 1 VWA von Willebrand factor type A domain 0.00043 21.4 0.0 0.0015 19.6 0.0 2.0 1 VWA_2 von Willebrand factor type A domain ------ inclusion threshold ------ 0.043 14.1 0.0 0.14 12.4 0.0 2.0 1 Tudor_2 Jumonji domain-containing protein 2A Tudor domain 0.064 13.3 0.0 0.26 11.3 0.0 2.1 1 VWA_4 von Willebrand factor A domain Domain annotation for each model (and alignments): >> DUF4537 Domain of unknown function (DUF4537) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 4.5 1.9e+04 53 66 .. 285 298 .. 280 302 .. 0.79 2 ! 72.9 0.0 7.4e-24 3.1e-20 1 117 [. 323 453 .. 323 456 .. 0.94 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 4.5 DUF4537 53 erplkvGDkVlalh 66 ++l+ D+Vla + FUN_001333-T1 285 SKVLQYADAVLASR 298 6789999****975 PP == domain 2 score: 72.9 bits; conditional E-value: 7.4e-24 DUF4537 1 gqkVlaRndedGfYyrgtvkkklsggvylvef......dakdtqvveesdiisledakerplkvGDkVlalhdpaeqsYiPgvVlag......... 81 g+kVlaR+++dG++y++tvk++ ++ +++vef ++ + q+v+ d+i+ +da ++ + +GDkVla+++ + +Y+Pg Vl g FUN_001333-T1 323 GMKVLARKESDGLFYLATVKQQGENDTFVVEFdqcpalRKPHLQEVALFDMIAYKDAIRHHVCIGDKVLAPWQHD-GRYGPGSVLDGvdrrdvqpk 417 789*****************************99999989999*****************************875.58*******88******999 PP DUF4537 82 vkkekeltVvfyngkkaklpreevyklskelYeeav 117 ++++++V+fyngk+++l ++ + +l+++ v FUN_001333-T1 418 GYNGGDILVAFYNGKTEQLSPGIAVRIPLNLFDRIV 453 8899***********************999999876 PP >> VWA_3 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.4 0.0 2e-13 8.6e-10 2 154 .. 27 181 .. 26 182 .. 0.90 Alignments for each domain: == domain 1 score: 39.4 bits; conditional E-value: 2e-13 VWA_3 2 evvilvDvsssmsgeieavkdalk..lalrqLptnd.kinilvfgtkarplfpgsrtvssreldeaaqfvktlqpplGgtnllqaLkealrqkekr 94 +vv+l+D+s sm + + vk+ l l+ r+ + +d +ni+ f +++++ +++ +r++ a +++ +l+ tn +aL ea + FUN_001333-T1 27 NVVFLIDTSGSMYHSLDVVKEHLLeiLFARAISGRDtMFNIIEFNEDVNKWANSLVACTPRTVSIASEWIHKLTC-GTSTNTMEALIEAYED---- 117 79*********99777999988863467899***9999*************************************.8899**********96.... PP VWA_3 95 gyvrsvilltdgspaqtservsdeisqargkirvhalglgstlsa....amLqeLAersrGtye 154 ++ + l+tdg p+qt +++ +++ ++hal l t+s L+eLA++++G + FUN_001333-T1 118 DGMDAIYLVTDGLPDQTPGVILENVRRLHKGRPIHALYLTGTHSDpaakVFLEELAKVTKGSFH 181 579************************778899*****9998887444446**********877 PP >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.0 1.6e-08 6.9e-05 1 129 [. 27 147 .. 27 194 .. 0.73 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 1.6e-08 VWA 1 DivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqyssevrte.fslndys..skeellsavkslkykgggttntgkalkyalenlf 93 ++vfl+D+Sgs+ ++ ++ vke l +++ i+ ++t ++++ ++++v + sl + + + + + + +++l + g++t nt +al +a+e FUN_001333-T1 27 NVVFLIDTSGSM-YHSLDVVKEHLLEILFARAISGRDTMFNIIEFNEDVNKWaNSLVACTprTVSIASEWIHKL-TCGTST-NTMEALIEAYE--D 117 79**********.***********************************99984455554455777777778885.444444.48888888877..3 PP VWA 94 kssagaRegapkvvvlltdGksqdg..dveeaarelks 129 ++ + l+tdG ++++ + e++r+l + FUN_001333-T1 118 DG--------MDAIYLVTDGLPDQTpgVILENVRRLHK 147 33........3358888888885534566667666665 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 3.5e-07 0.0015 1 86 [. 28 115 .. 28 130 .. 0.79 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 3.5e-07 VWA_2 1 lvfvlDnSgSmrngdygptrleaakdaveallksl....pgdrvglvtfsdnpevlipl....t.kdkakllealrrleatgggtdlaaAlqlar 86 +vf++D+SgSm + l+ +k+ + ++l ++ + ++++ f +++++ ++ t ++ + + e +++l++ g t++ +Al a FUN_001333-T1 28 VVFLIDTSGSMYHS------LDVVKEHLLEILFARaisgRDTMFNIIEFNEDVNKWANSlvacTpRTVSIASEWIHKLTC-GTSTNTMEALIEAY 115 79***********9......*********9999776664567**********9888864455456778888889999997.59999998886655 PP >> Tudor_2 Jumonji domain-containing protein 2A Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 3.4e-05 0.14 3 32 .. 325 355 .. 323 356 .. 0.85 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 3.4e-05 Tudor_2 3 dVivrw.tDGryYlakfigihtqtfYeVeFE 32 +V++r +DG++Yla++++ + VeF+ FUN_001333-T1 325 KVLARKeSDGLFYLATVKQQGENDTFVVEFD 355 67776449************99999999998 PP >> VWA_4 von Willebrand factor A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 6e-05 0.26 2 45 .. 28 70 .. 27 77 .. 0.78 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6e-05 VWA_4 2 LvfviDttgsMseeieavkekaesiiksklgtkkepekyiLvpF 45 +vf+iDt+gsM++ ++ vke+ +i+ +++ + + + + +++F FUN_001333-T1 28 VVFLIDTSGSMYHSLDVVKEHLLEILFARAISG-RDTMFNIIEF 70 69**********************998776433.3344555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (934 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2913 (0.114034); expected 510.9 (0.02) Passed bias filter: 607 (0.023762); expected 510.9 (0.02) Passed Vit filter: 120 (0.00469759); expected 25.5 (0.001) Passed Fwd filter: 29 (0.00113525); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.54u 0.46s 00:00:01.00 Elapsed: 00:00:00.44 # Mc/sec: 8650.09 // Query: FUN_001334-T1 [L=156] Description: FUN_001334 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.07 14.3 1.2 2.4 9.4 0.2 2.9 3 Bact_transglu_N Bacterial transglutaminase-like N-terminal r Domain annotation for each model (and alignments): >> Bact_transglu_N Bacterial transglutaminase-like N-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.012 3.1e+02 44 66 .. 48 70 .. 25 82 .. 0.81 2 ? -1.2 0.0 0.19 4.8e+03 46 60 .. 83 97 .. 71 102 .. 0.80 3 ? 9.4 0.2 9.6e-05 2.4 22 51 .. 101 130 .. 94 152 .. 0.76 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.012 Bact_transglu_N 44 epaeiseqrDafgnrvarfsfde 66 ep+ ++ +Daf+ ++++++++ FUN_001334-T1 48 EPKVHTSIEDAFDTVLQYMNVTS 70 56666999*********999976 PP == domain 2 score: -1.2 bits; conditional E-value: 0.19 Bact_transglu_N 46 aeiseqrDafgnrva 60 +e+s+q D++ nr + FUN_001334-T1 83 EERSSQDDHHCNRFH 97 467889999999887 PP == domain 3 score: 9.4 bits; conditional E-value: 9.6e-05 Bact_transglu_N 22 lrLrPrsspgqrvlsyslkisPepaeiseq 51 L Pr +p qr+++ ++++ P ++s FUN_001334-T1 101 YNLVPRGHPLQRMEDVQVEVAPGSYAVSAG 130 5699******************98887544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (156 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 956 (0.0374242); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1595.55 // Query: FUN_001335-T1 [L=512] Description: FUN_001335 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-34 119.0 0.0 4e-34 118.5 0.0 1.2 1 Copine Copine 7.8e-22 78.0 0.0 7.8e-12 45.8 0.0 2.5 2 C2 C2 domain Domain annotation for each model (and alignments): >> Copine Copine # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 118.5 0.0 3.2e-38 4e-34 1 154 [. 356 509 .. 356 511 .. 0.97 Alignments for each domain: == domain 1 score: 118.5 bits; conditional E-value: 3.2e-38 Copine 1 sLHyispeqpneYekallsvgeilqaydsdklipafGFGaklpsdaevsdefvlnfneenkevegiegvleaYrealpnlqlygPTnfapiiekva 96 sLH+ + e++neY + l +g++l+++ +d++ipa+GFGak +s + f+l+ + + e + i+ ++ aY + l++++l gPT +ap+++++a FUN_001335-T1 356 SLHTSD-EEKNEYVRTLAYLGKVLTTFGEDHKIPAYGFGAKAASTGPLPYMFALDSEGGQLELDTIDSIIDAYWKRLEDVSLGGPTYLAPVVQEIA 450 799877.99*************************************************************************************** PP Copine 97 kiaea.stkeasqYfvLliitDGvvtdmketidaiveAsklplSiiivGvGdadfeemr 154 ae+ ++++++Y + l+i DG+v d+++ i+ +++ +lplSi++vGvG +df m FUN_001335-T1 451 AYAEKeVSQSSQHYTIGLVIVDGIVNDVDNLIEKLIDIGHLPLSIVVVGVGPTDFRLMV 509 *****8999999*******************************************9995 PP >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.8 0.0 6.1e-16 7.8e-12 8 95 .. 58 153 .. 55 163 .. 0.88 2 ! 29.5 0.0 7.5e-11 9.5e-07 9 95 .. 194 288 .. 187 295 .. 0.92 Alignments for each domain: == domain 1 score: 45.8 bits; conditional E-value: 6.1e-16 C2 8 ieaknLpkkdkkgksdpyvkvkl...kdgkqkkkTkvvkktlnPvWnetftfevpeleeevLeieVyd.....kdrlskddflGeveiplseldsg 95 +++++L d ++ksdp++++++ +++ + +T+ + ++l+P++ etf +e ++ ++L+++++d ++ l+k+df+G +ei +++l ++ FUN_001335-T1 58 LRCTDLVLLDSFTKSDPMCVLYVkkfGQWMEYGRTESIPNCLQPKFVETFIIEANKTIYSRLRFSIFDlanftSKDLRKHDFIGSFEIEMESLLDS 153 68999*999***********************************************************6655433379999*********995443 PP == domain 2 score: 29.5 bits; conditional E-value: 7.5e-11 C2 9 eaknLpkkdkkgksdpyvkvkl.....kdgkqkkkTkvvkktlnPvWnetftfevpe....leeevLeieVydkdrlskddflGeveiplseldsg 95 a nL+kk gk+d++ +v+ ++ + ++++++v +t P+W f +++++ + ++ ++++++++ +++ +lGe+++p+++l ++ FUN_001335-T1 194 GASNLAKKGLLGKCDAFFEVNRwicnaGRFHPVYRSEIVTRTAAPKW-APFDISLQKlcndNVDGQILVSCWHFSNSGNHSILGEARLPIKTLFHR 288 699*****99**********9999***9**************99***.99999999999999999***********9**************97665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (512 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 606 (0.0237228); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 5072.61 // Query: FUN_001336-T1 [L=504] Description: FUN_001336 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-24 85.5 35.5 6.4e-24 85.0 35.5 1.1 1 Na_H_Exchanger Sodium/hydrogen exchanger, transmembrane Domain annotation for each model (and alignments): >> Na_H_Exchanger Sodium/hydrogen exchanger, transmembrane # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.0 35.5 2.5e-28 6.4e-24 1 364 [. 75 454 .. 73 464 .. 0.86 Alignments for each domain: == domain 1 score: 85.0 bits; conditional E-value: 2.5e-28 Na_H_Exchanger 1 illallapllarrlk...lPeivllilaGlllGpsglgliept.......edlevlsnlgliflLFlaGleldlrelrknlksilllallgvlit 85 i+la+l+++l rrl lP +++++++G +l ++ + +++ l l+++L +Gleld l++ +++ la+ + FUN_001336-T1 75 IVLAALGGFLTRRLSkdaLPSLLGMLIVGFILRNVPGV----DvaryidkTWSAGLRSMALVVILTRSGLELDPGALKRLKFAVIRLAFCPCIGE 165 5678888889999999****************998544....22355789***************************************999999 PP Na_H_Exchanger 86 lvliGlllylllllgiplleallfgailsatdpvavlailk....eegrvnerlgtlllgesvlnDivavvllavllala.gengglsdllslll 175 +++++++ +l ll++p+l ++ +g++l a+ p++v++ l + v++ + tl++++s ++D++a+ l+ v+l++a ++++ +++++ + + FUN_001336-T1 166 AITVAVVGKL--LLDMPWLWGFQLGFVLGAVTPAVVVPQLLtlqaKGFGVKQGIPTLVMAASSFDDVIAISLFGVFLGIAfSKGNLVFNIFRGPI 258 9999998887..79************************99977777789********************************************** PP Na_H_Exchanger 176 iflvvavgglllglliglllrlitrfteddrelevllvlllvllaallaellgvs..gilgaflaGlvlseyeeane...lseklesfgeglfep 265 ++l +v+g l+gll ++l+ ++ + +++ l +ll+++ + ++s g+lg++++ + s + ++e + + ++ +f p FUN_001336-T1 259 ELLMGVVFGSLVGLLCWFLPNKMEAD---RSRNRFVILLGCALLSVFGSNKAQFSgaGALGVLVLATMASYGWGDSEkapVADAMAIVW-EFFQP 349 *************************5...555556666666666666666665552278***********4444443334777799999.9**** PP Na_H_Exchanger 266 lfFvllGlsldlsvllkhlsvlilvllilvaillvrflgvllllrllglslrealilgllglqrgavalalaaigpaa.......gliarel.ya 352 l+F l+G+++ ++ ++ ++ ++++l + +++r ++++l+ + ls re+++++++ +++ +v +a+ ++ ++ g ++el + FUN_001336-T1 350 LLFGLIGAEVSIEYMD--SALIGKAFGLLTVAMVIRMIITFLVVSGNSLSVREKIFVAIAWSPKATVQAAIGSLSLDIarergfaGMRQEELgIQ 442 ***************7..99*********9999************99************************999988756666665555566666 PP Na_H_Exchanger 353 llivvvlftllv 364 +l+++vl l+ FUN_001336-T1 443 ILTIAVLSILFT 454 666666655553 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (504 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 834 (0.0326483); expected 510.9 (0.02) Passed bias filter: 378 (0.0147974); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4982.71 // Query: FUN_001336-T2 [L=399] Description: FUN_001336 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (399 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 752 (0.0294382); expected 510.9 (0.02) Passed bias filter: 378 (0.0147974); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3856.20 // Query: FUN_001337-T1 [L=138] Description: FUN_001337 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-22 79.8 1.6 2.1e-22 79.4 1.6 1.2 1 MitoNEET_N Iron-containing outer mitochondrial membrane prot 3.5e-10 40.5 0.1 7e-10 39.5 0.1 1.5 1 zf-CDGSH Iron-binding zinc finger CDGSH type Domain annotation for each model (and alignments): >> MitoNEET_N Iron-containing outer mitochondrial membrane protein N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.4 1.6 1.6e-26 2.1e-22 1 62 [. 1 62 [. 1 64 [. 0.97 Alignments for each domain: == domain 1 score: 79.4 bits; conditional E-value: 1.6e-26 MitoNEET_N 1 MeslsrvvksslPnyLkslPiPkSfggifrLslkdwLalvpfaavtaalgYlaykaflpkkk 62 Me+ srvvk +lPnyLk lP+P fgg+ +Ls ++w++lvpf+++t++++Yl++ a+lp FUN_001337-T1 1 MEVFSRVVKIQLPNYLKALPVPSTFGGFTKLSSNEWVQLVPFVVTTSVVVYLVVSALLPSSS 62 9********************************************************99876 PP >> zf-CDGSH Iron-binding zinc finger CDGSH type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.5 0.1 5.5e-14 7e-10 28 48 .] 93 116 .. 71 116 .. 0.73 Alignments for each domain: == domain 1 score: 39.5 bits; conditional E-value: 5.5e-14 zf-CDGSH 28 v...vaLCrCgrSknkPfCDgsHk 48 + +CrC++Sk++P+CDgsH+ FUN_001337-T1 93 LgdkTVYCRCWKSKKFPLCDGSHN 116 25559******************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (138 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 671 (0.0262674); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1392.46 // Query: FUN_001338-T1 [L=1573] Description: FUN_001338 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-77 259.0 0.0 5.8e-38 130.7 0.1 2.6 2 MAM MAM domain, meprin/A5/mu 1.5e-22 80.1 77.5 4.3e-09 37.0 5.4 6.9 4 TSP1_ADAMTS Thrombospondin type 1 domain 2.7e-19 69.8 8.2 2.7e-19 69.8 8.2 5.6 3 ADAMTS_CR_2 ADAMTS cysteine-rich domain 2 1.6e-15 58.2 0.0 3e-15 57.3 0.0 1.5 1 Reprolysin Reprolysin (M12B) family zinc metalloproteas 2.6e-13 50.3 0.1 2.8e-05 24.5 0.0 2.5 2 VHL VHL beta domain 6.3e-13 49.2 16.0 1.2e-11 45.1 5.9 7.0 6 TSP_1 Thrombospondin type 1 domain 7.8e-12 46.1 0.7 1.7e-11 45.1 0.7 1.6 1 Pep_M12B_propep Reprolysin family propeptide 1.9e-10 41.7 0.0 6.7e-10 40.0 0.0 2.0 1 Reprolysin_5 Metallo-peptidase family M12 1.4e-09 38.7 0.0 2.9e-09 37.7 0.0 1.6 1 ADAMTS_spacer1 ADAM-TS Spacer 1 8.3e-07 30.0 0.0 1.6e-06 29.1 0.0 1.5 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-lik 1.9e-06 28.3 0.0 5.9e-06 26.8 0.0 1.8 1 Reprolysin_2 Metallo-peptidase family M12B Reprolysin-lik 2.4e-06 28.2 7.4 2.4e-06 28.2 7.4 7.9 6 TSP1_spondin Spondin-like TSP1 domain 7.8e-06 26.4 6.9 2.5e-05 24.7 6.9 1.9 1 ADAMTS_CR_3 ADAMTS cysteine-rich domain 4.2e-05 24.7 9.3 0.00022 22.3 9.3 2.4 1 PLAC PLAC (protease and lacunin) domain 0.0016 18.8 10.2 0.0077 16.6 10.2 2.2 1 ADAMTS_C ADAMTS C-terminal helical domain 0.0093 16.7 1.0 0.0093 16.7 1.0 8.4 5 TSP1_CCN CCN3 Nov like TSP1 domain ------ inclusion threshold ------ 0.022 14.8 0.1 0.048 13.7 0.1 1.5 1 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-lik 0.046 14.1 0.0 0.098 13.0 0.0 1.5 1 Peptidase_M10 Matrixin 0.066 14.0 18.8 0.091 13.6 5.7 3.3 2 Adt-1 Adt-1-like domain 0.086 12.5 0.2 0.15 11.8 0.2 1.2 1 DUF4953 Met-zincin Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 125.8 0.0 1.5e-39 1.9e-36 1 157 [. 830 985 .. 830 986 .. 0.94 2 ! 130.7 0.1 4.5e-41 5.8e-38 1 158 [] 1368 1525 .. 1368 1525 .. 0.94 Alignments for each domain: == domain 1 score: 125.8 bits; conditional E-value: 1.5e-39 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgss..kgtlrv 91 CdFe+g lCgwt+d +dd dW+r+++ ++ tgps dht+ + Ghy++lets+ +g +arL+s+ + + Cl+Fwyh +g + g+l++ FUN_001338-T1 830 CDFENG-LCGWTNDRQDDYDWRRHRGRtpTAGTGPSVDHTKGKLGHYVFLETSRPiGPGWKARLVSKYVGMRVA--CLKFWYHAFGGNihMGELQL 922 ******.*****************9999**************************99************999866..*********87733677777 PP MAM 92 llreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 ++++ +e ++ ws+++++g++W vt+ + +++++++f+++rg+g+ +d+ lDdisl++++C FUN_001338-T1 923 RIKTDVGE--NVAWSVNKNRGNRWVLKYVTIFS-KRPYRIIFQGIRGDGYLSDFGLDDISLENNPC 985 77777777..***********************.******************************** PP == domain 2 score: 130.7 bits; conditional E-value: 4.5e-41 MAM 1 CdFeegslCgw...tqdesddadWervsaa..sektgpssdht.etgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskg 87 C+Fe g +C+w ++++ d++dW+ ++++ s++tgps+dht +t+ G y ++e+s+ +++++arL+sp+l+a++ C++Fwyhm+g + g FUN_001338-T1 1368 CTFEAG-FCHWknmRNSQLDQFDWTLRNGStpSRNTGPSNDHTlGTSRGVYAYIEASEPqQRNDRARLISPVLKARRA--CIDFWYHMYGAHTG 1458 ******.***955345666777*****9999**************************9989999***********988..************** PP MAM 88 tlrvllreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeCk 158 lrv+ ++++e+ lw g+q+++W++a++ + + ++q++fe++rg+g ++dialDdi++++g+C+ FUN_001338-T1 1459 WLRVMSKRTTEQ---RLWFKLGNQKNEWHNARLYIFS-YVPYQIIFEGTRGRGFASDIALDDIKITSGRCP 1525 ******999999...99999*****************.********************************6 PP >> TSP1_ADAMTS Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 7.5 1.7e-05 0.022 5 55 .] 741 787 .. 736 787 .. 0.90 2 ! 37.0 5.4 3.3e-12 4.3e-09 1 55 [] 1190 1245 .. 1190 1245 .. 0.92 3 ! 33.7 10.1 3.5e-11 4.4e-08 1 55 [] 1250 1303 .. 1250 1303 .. 0.98 4 ! 29.8 8.5 6e-10 7.7e-07 1 55 [] 1307 1358 .. 1307 1358 .. 0.98 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.7e-05 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 + s Cs++CG Gv +R+ +C + + ++ ++C+ k +++ Cn k+C FUN_001338-T1 741 ELSACSRSCGVGVHYRTRKCNNPVPQ--NDGRQCE--GKDIKFELCNVKDC 787 5579*******************999..579****..8999********99 PP == domain 2 score: 37.0 bits; conditional E-value: 3.3e-12 TSP1_ADAMTS 1 WkagkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkP.setqsCnlkpC 55 W+ kWs+CsktCG+G++t +C+++++++++++++C + +kP ++ + Cnl +C FUN_001338-T1 1190 WSHFKWSDCSKTCGEGIRTELFKCIEQDNNTEVEEHHCYSINKPaPRNKFCNLTAC 1245 88889*************************999*******7777356788****99 PP == domain 3 score: 33.7 bits; conditional E-value: 3.5e-11 TSP1_ADAMTS 1 WkagkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 W + +Ws+Cs +C gG qtR+ C+ + ++++s Cs + +P+++q+Cn ++C FUN_001338-T1 1250 WIVSQWSKCSSPCNGGNQTRTTECRGLLTGVKVNSSLCS-RVRPKTKQECNVHSC 1303 999**************************9999******.*************** PP == domain 4 score: 29.8 bits; conditional E-value: 6e-10 TSP1_ADAMTS 1 WkagkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 W +g+Ws+C +tCG+ q+R+v C++ g+ + +C + kP++++ C++kpC FUN_001338-T1 1307 WIVGNWSKCRTTCGSWPQYRSVWCRNILGE---LSLNCPRDVKPPSRRICRNKPC 1358 99*************************999...689******************* PP >> ADAMTS_CR_2 ADAMTS cysteine-rich domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.8 8.2 2.1e-22 2.7e-19 1 69 [] 641 713 .. 641 713 .. 0.91 2 ? 0.1 0.5 1.2 1.6e+03 31 68 .. 1005 1040 .. 992 1041 .. 0.70 3 ? 0.2 0.8 1.2 1.5e+03 11 39 .. 1330 1362 .. 1326 1378 .. 0.78 Alignments for each domain: == domain 1 score: 69.8 bits; conditional E-value: 2.1e-22 ADAMTS_CR_2 1 PGqlysadeQCrlifgpeskkcpkkeesvCkklwCskpek....ekecktkeapaadgTsCgekkwClkgkCv 69 PGqly++d+QC+ fg++s++c+ ++ + Ck+lwC + + ++ c+tk++pa++gT+Cg++kwC+ gkCv FUN_001338-T1 641 PGQLYTIDAQCQREFGSNSRFCRGMKRDPCKQLWCIRLSYvslnNRFCQTKSEPALEGTQCGQNKWCRLGKCV 713 9************************9*********764322223899*************************8 PP == domain 2 score: 0.1 bits; conditional E-value: 1.2 ADAMTS_CR_2 31 kklwCskpekekecktkeapaadgTsCgekk....wClkgkC 68 ++ +C+ +++ ++ ++ +gT C + +C+ g+C FUN_001338-T1 1005 QQ-FCQASSN-----VAQVEVENGTACHDSLrsfdVCILGQC 1040 44.4665443.....467888999999976434449999999 PP == domain 3 score: 0.2 bits; conditional E-value: 1.2 ADAMTS_CR_2 11 Crlifgpeskkcpkk.e...esvCkklwCskpe 39 Cr i g+ s +cp+ + ++C++ C+ + FUN_001338-T1 1330 CRNILGELSLNCPRDvKppsRRICRNKPCEGEI 1362 99999**9*****88667778999998888754 PP >> Reprolysin Reprolysin (M12B) family zinc metalloprotease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.3 0.0 2.3e-18 3e-15 1 199 [. 428 628 .. 428 629 .. 0.85 Alignments for each domain: == domain 1 score: 57.3 bits; conditional E-value: 2.3e-18 Reprolysin 1 kYvelfivvdkqlfkklgsdtekvrqkvlevvnlvnsiyke..lnirvvLvglEiW...tdedkievskdaeetLeeflkwreeklk.....krkk 86 kY+e++ +d+++ k +g +ek ++ +l ++n+v +y++ + + v v + + +d +i+++ ++ L+ w ++++k ++ FUN_001338-T1 428 KYIEVMATADSSVIKFHG--KEKSEKYILTLMNIVSRLYQHksIGTPVYFVVVKLVlleNDPKEIKINGKPMPSLSSVCYWGHKTRKgfdssTKDF 521 8*****************..567789*************9766888887666665411156678*****************999876333324666 PP Reprolysin 87 hdaaqLlsgkefeaktvglayvgglCskeksgavnedkkknlealavilaheLghnlGlqhdeekkeCkCeekgvCimneeagsssgv.kFskcsl 181 +d+++++++k+f +g a v+g+C +++s+++ne+ + a i+ahe gh lG++hd +++C+ + ++ im + + s + + +s+cs+ FUN_001338-T1 522 YDQTVFITRKDFGP--SGYAPVHGMCWRTRSCTLNEED---GFTSAFIIAHETGHTLGMEHDGVNNNCSNDVIKGSIMAPLVRSRFDRfYWSSCSR 612 89**********99..9*****************9987...778899**********************999********99999999899***** PP Reprolysin 182 edfekflkkqkgaCLlnk 199 +d+ + l+ CL + FUN_001338-T1 613 RDLISKLR--ALWCLNDV 628 99876554..45566665 PP >> VHL VHL beta domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 6.1e-08 7.8e-05 7 76 .. 227 295 .. 222 301 .. 0.90 2 ! 24.5 0.0 2.2e-08 2.8e-05 6 78 .. 324 395 .. 321 399 .. 0.92 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 6.1e-08 VHL 7 rvaaqvifcnrsPrvvkpvWidfeGePrpyvelkPgtGrrittylghlWlfrdaesddgllvnqkelflp 76 ++a v+f n + r vk+ +i +G + l+ + + ++t+ h W+ rd ++ l++n++ f + FUN_001338-T1 227 TESAYVLFVNSAGRAVKLYYI-VDGTETLFRVLEDRATKSVNTFTVHGWIARDYDTGKQLVINRERTFYA 295 56788************9999.69***************************************9988865 PP == domain 2 score: 24.5 bits; conditional E-value: 2.2e-08 VHL 6 srvaaqvifcnrsPrvvkpvWidfeGePrpyvelkPgtGrrittylghlWlfrdaesddgllvnqkelflpsa 78 s+ +++ f nrs r vk+ +i+ Ge +++l P ++ty h W+ +d ++ l vn+++ + p++ FUN_001338-T1 324 SQPNSHLSFINRSNRFVKLYYIE-AGETIFFHNLPPHDVILVNTYTSHRWFAKDLDTLKVLHVNGQNQYAPEE 395 56677889**************9.7*****************************************9998875 PP >> TSP_1 Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.1 5.9 9e-15 1.2e-11 1 49 [] 737 787 .. 737 787 .. 0.98 2 ? -2.3 1.3 6.2 7.9e+03 13 49 .] 1008 1040 .. 997 1040 .. 0.65 3 ! 19.4 2.4 9.6e-07 0.0012 5 27 .. 1194 1216 .. 1190 1245 .. 0.75 4 ! 12.3 9.2 0.00016 0.2 4 49 .] 1253 1303 .. 1251 1303 .. 0.76 5 ! 12.3 6.5 0.00016 0.2 4 49 .] 1310 1358 .. 1308 1358 .. 0.95 6 ? -2.0 0.5 4.9 6.2e+03 24 44 .. 1524 1542 .. 1519 1546 .. 0.76 Alignments for each domain: == domain 1 score: 45.1 bits; conditional E-value: 9e-15 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 s w+e s+Cs +Cg G+ R+R c++p q++g +C+g+++++e C+ k C FUN_001338-T1 737 SSWTELSACSRSCGVGVHYRTRKCNNPvpQNDGRQCEGKDIKFELCNVKDC 787 78**********************************************999 PP == domain 2 score: -2.3 bits; conditional E-value: 6.2 TSP_1 13 CgkGirvRqRtckspqkggepCtgeaqeteaCkmkkC 49 C + v q + +g++C + + +++C +C FUN_001338-T1 1008 CQASSNVAQVEVE----NGTACHDSLRSFDVCILGQC 1040 5555544444444....58999999999999966555 PP == domain 3 score: 19.4 bits; conditional E-value: 9.6e-07 TSP_1 5 eWspCsvTCgkGirvRqRtcksp 27 +Ws+Cs+TCg+Gir++ c + FUN_001338-T1 1194 KWSDCSKTCGEGIRTELFKCIEQ 1216 6*************998777666 PP == domain 4 score: 12.3 bits; conditional E-value: 0.00016 TSP_1 4 seWspCsvTCgkGirvRqRtcksp....qkggepCtgeaqe.teaCkmkkC 49 s+Ws+Cs +C G ++R+ c + + +++ C+ + + C+ + C FUN_001338-T1 1253 SQWSKCSSPCNGGNQTRTTECRGLltgvKVNSSLCSRVRPKtKQECNVHSC 1303 89*******************998777666666676543332567777777 PP == domain 5 score: 12.3 bits; conditional E-value: 0.00016 TSP_1 4 seWspCsvTCgkGirvRqRtcksp.qkggepCtgeaqe..teaCkmkkC 49 + Ws+C +TCg+ + R+ c + + + +C+ ++++ ++C++k+C FUN_001338-T1 1310 GNWSKCRTTCGSWPQYRSVWCRNIlGELSLNCPRDVKPpsRRICRNKPC 1358 68********************99999999******98889*******9 PP == domain 6 score: -2.0 bits; conditional E-value: 4.9 TSP_1 24 ckspqkggepCtgeaqeteaC 44 c ++q ++ +C g+++ + C FUN_001338-T1 1524 CPKKQPNQDQCRGDKS--RYC 1542 7777789999999985..466 PP >> Pep_M12B_propep Reprolysin family propeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.1 0.7 1.3e-14 1.7e-11 2 91 .. 46 133 .. 45 135 .. 0.87 Alignments for each domain: == domain 1 score: 45.1 bits; conditional E-value: 1.3e-14 Pep_M12B_propep 2 vviPvrvdasgeflshels...skrrrrslseeeeseeqlsYrlsaegkelhLnLeknrellapgftvetygkdgeevtespqeeehChYqGh 91 v++P+++d+s ++ h + ++rrrrs++ e+ e + Y+++++g+ ++ L++n++l++++ftve ++++g+ +t+ + +e+C+ +G+ FUN_001338-T1 46 VTYPTELDHSFRVTDHVTTlssHTRRRRSVTGES---EPVIYQVQFKGQSIRMVLKLNTKLFGSSFTVERHKENGSIETK--TVTEQCYLVGE 133 8999999998888888555668999****98775...89******************************99999987776..45589****97 PP >> Reprolysin_5 Metallo-peptidase family M12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.0 0.0 5.3e-13 6.7e-10 3 194 .. 428 605 .. 426 606 .. 0.78 Alignments for each domain: == domain 1 score: 40.0 bits; conditional E-value: 5.3e-13 Reprolysin_5 3 rkvallvaaDcsyvaafggdaaqaniinmvntasnvyeref...nislglanltisdstdpetase....asssgnssdlLnefqsssawrgtqsd 91 + + +++ aD s + +g ++ +++i++++n +s++y++++ + +++++l+ ++++ +e + + + s +++ ++ ++ + ++++ FUN_001338-T1 428 KYIEVMATADSSVIKFHGKEKSEKYILTLMNIVSRLYQHKSigtPVYFVVVKLVLLENDPKEIKINgkpmP-SLSSVCYWGHKTRKGFDSSTKDFY 522 6688999**********7799********************999999******999998887655566532.223333333343344444556777 PP Reprolysin_5 92 dlavltlmtncstgvglAwlgqlcnsgsagsvsesveksnsvvvstatewqvfaHEiGHnfGavHDcdsstassqcCplsastcdaggryiMnpss 187 d v+++ ++++ g+A + ++c+ + + ++e + t++ ++aHE+GH++G +HD ++ C+ +d iM+p + FUN_001338-T1 523 DQTVFITRKDFGPS-GYAPVHGMCWRTRSCTLNEE---------DGFTSAFIIAHETGHTLGMEHDGVNN-----NCS-----NDVIKGSIMAPLV 598 778888888*****.**********9998888888.........4568999****************953.....553.....4677888999888 PP Reprolysin_5 188 spnitaf 194 ++ ++f FUN_001338-T1 599 RSRFDRF 605 8777776 PP >> ADAMTS_spacer1 ADAM-TS Spacer 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.7 0.0 2.3e-12 2.9e-09 11 115 .] 1080 1181 .. 1070 1181 .. 0.86 Alignments for each domain: == domain 1 score: 37.7 bits; conditional E-value: 2.3e-12 ADAMTS_spacer1 11 akgYvtvvtiPagatsikvrerkpsfthLAvkn.vqgkyilngkgsislsstelsllgtvleYrrslpalEeleasgPlqeeleiqvlrqygk 102 +++ t+++ P gat+i ++++p+ L+ + ++ + + + +s t ++++g +++Yrr + ++E ++a gP+++++ ++v + g FUN_001338-T1 1080 KEDLQTLLECPVGATNIMLKDSSPNDLILVAMGeKKPRIDVTDEKLVS---TAYEFAGSKFTYRR-EGDKEAITALGPIKDKIMVKVRMGDGG 1168 6667899******************98887775355566677777766...**************.************************999 PP ADAMTS_spacer1 103 atnpdikYeYfip 115 at +++Y+++ p FUN_001338-T1 1169 ATPVNLQYQFYKP 1181 **********965 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.1 0.0 1.3e-09 1.6e-06 2 123 .] 451 578 .. 450 578 .. 0.83 Alignments for each domain: == domain 1 score: 29.1 bits; conditional E-value: 1.3e-09 Reprolysin_3 2 ariaslveaanqvye.relg..irlqlaaiiitssa.dtpyttkdaleildeaaevist......ergqsgydlvhlftkrdvsgvgGlAyvgavc 87 ++i +l++ ++ y+ + +g + + +++++ ++ + ++ + ++++ l++ + ++ ++ ++ yd +++t++d+ g G A v ++c FUN_001338-T1 451 KYILTLMNIVSRLYQhKSIGtpVYFVVVKLVLLENDpKEIKINGKPMPSLSSVCYWGHKtrkgfdSSTKDFYDQTVFITRKDF-GPSGYAPVHGMC 545 589999*********77777999999998887766514666666667777777666666777886578999***********9.************ PP Reprolysin_3 88 nsskkfglnsgssplgdtgadtfaHEiGHnfGanHt 123 +++ ln+++ g t+a +aHE GH +G +H+ FUN_001338-T1 546 WRTRSCTLNEED---GFTSAFIIAHETGHTLGMEHD 578 *********999...57789***************8 PP >> Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 4.6e-09 5.9e-06 5 188 .. 450 614 .. 447 620 .. 0.70 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 4.6e-09 Reprolysin_2 5 teelvevlnrvnqiYeeddieislglrneaeieattsasdsgnn......rcnssttevrrlnllsqlegekdydlahlvllgefsggvlGLAyvg 94 + +++++n v+++Y++ i++ + ++ ++ + + + ++ + n +++ + + + ++ + yd +++++ ++f g G A v FUN_001338-T1 450 EKYILTLMNIVSRLYQHKSIGTPVYFVVVKLVLLENDPKEIKINgkpmpsLSSVCYWGHKTRKGFDSSTK-DFYDQTVFITRKDF--GPSGYAPVH 542 67899*********************97666666666666666655555533444554444666665443.56788888877777..567****** PP Reprolysin_2 95 qicqkkassrktntglsttanygsaveesqeidvvaHEvGHnFGatHdndgsssasegceenaatsaesangkfiMapa..sksnntqFSpcsisl 188 ++c ++ s+ t +n ++ ++ ++aHE GH+ G Hd + ++s+ + +iMap s + +S cs+ FUN_001338-T1 543 GMCWRTRSC----T-----LNEEDGF---TSAFIIAHETGHTLGMEHDGVNN-NCSN-----------DVIKGSIMAPLvrSRFDRFYWSSCSRRD 614 *********....4.....6666666...4899***************8744.4442...........2233468887744445555557787765 PP >> TSP1_spondin Spondin-like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 7.4 1.9e-09 2.4e-06 4 52 .] 737 787 .. 735 787 .. 0.93 2 ? -1.5 1.5 3.7 4.7e+03 12 52 .] 1004 1040 .. 1001 1040 .. 0.72 3 ! 15.1 1.4 2.4e-05 0.03 8 33 .. 1194 1219 .. 1188 1242 .. 0.79 4 ! 14.3 11.8 4.1e-05 0.053 1 52 [] 1245 1303 .. 1245 1303 .. 0.91 5 ? 4.2 8.0 0.059 75 7 52 .] 1310 1358 .. 1306 1358 .. 0.79 6 ? -0.3 0.7 1.5 2e+03 37 50 .. 1523 1537 .. 1518 1539 .. 0.86 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.9e-09 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRevive.pqnggkpCpell.errkCneepC 52 s+W+e s Cs++Cg Gv++RtR+ + pqn+g++C + + + Cn + C FUN_001338-T1 737 SSWTELSACSRSCGVGVHYRTRKCNNPvPQNDGRQCEGKDiKFELCNVKDC 787 889999******************76549***********9********99 PP == domain 2 score: -1.5 bits; conditional E-value: 3.7 TSP1_spondin 12 CsktCgkGvqtRtRevivepqnggkpCpell.errkCneepC 52 C++ C+ ++ +v + + ++g +C ++l C +C FUN_001338-T1 1004 CQQFCQASS-----NVAQVEVENGTACHDSLrSFDVCILGQC 1040 555554444.....4556666999999999988899988888 PP == domain 3 score: 15.1 bits; conditional E-value: 2.4e-05 TSP1_spondin 8 eWseCsktCgkGvqtRtRevivepqn 33 +Ws+CsktCg+G++t + i +++n FUN_001338-T1 1194 KWSDCSKTCGEGIRTELFKCIEQDNN 1219 7************9976666555555 PP == domain 4 score: 14.3 bits; conditional E-value: 4.1e-05 TSP1_spondin 1 CvvseW..seWseCsktCgkGvqtRt...RevivepqnggkpCpell..errkCneepC 52 C++ eW s+Ws+Cs+ C++G qtRt R +++ + + + C + +++Cn ++C FUN_001338-T1 1245 CEIYEWivSQWSKCSSPCNGGNQTRTtecRGLLTGVKVNSSLCSRVRpkTKQECNVHSC 1303 999999889****************9666778999*********999889999****99 PP == domain 5 score: 4.2 bits; conditional E-value: 0.059 TSP1_spondin 7 seWseCsktCgkGvqtRtRevivepqnggkpCpell...errkCneepC 52 ++Ws+C +tCg+ q+R+ + +Cp++ rr C+++pC FUN_001338-T1 1310 GNWSKCRTTCGSWPQYRSVWCRNILGELSLNCPRDVkppSRRICRNKPC 1358 58********888888775444445566788999887888999999999 PP == domain 6 score: -0.3 bits; conditional E-value: 1.5 TSP1_spondin 37 pCpell.errkCnee 50 +Cp+++ ++ +C+++ FUN_001338-T1 1523 RCPKKQpNQDQCRGD 1537 7***********876 PP >> ADAMTS_CR_3 ADAMTS cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 6.9 2e-08 2.5e-05 78 115 .] 1031 1068 .. 1005 1068 .. 0.89 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 2e-08 ADAMTS_CR_3 78 tlslcvsgscrtfgcdgrmdsqqvwdrcqvcggdnstc 115 ++ +c+ g c+++gcdg m s++ drc vcgg + tc FUN_001338-T1 1031 SFDVCILGQCQVVGCDGVMGSNKTLDRCGVCGGKDDTC 1068 4579********************************99 PP >> PLAC PLAC (protease and lacunin) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 9.3 1.7e-07 0.00022 3 30 .. 1537 1564 .. 1534 1565 .. 0.94 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 1.7e-07 PLAC 3 DkfanCelVvqarlCshkyYrkfCCkSC 30 Dk+++C+++vq++ C k +++CCk+C FUN_001338-T1 1537 DKSRYCRVAVQLNWCLSKRWSQACCKTC 1564 88************************** PP >> ADAMTS_C ADAMTS C-terminal helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 10.2 6e-06 0.0077 5 41 .. 1533 1568 .. 1532 1571 .. 0.91 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 6e-06 ADAMTS_C 5 kCvgDrWtvyCrViReknLCQDmRWyQrccetcrdiy 41 +C gD+ + yCrV + n C +RW Q cc+tc+ ++ FUN_001338-T1 1533 QCRGDK-SRYCRVAVQLNWCLSKRWSQACCKTCERVT 1568 588887.89************************9876 PP >> TSP1_CCN CCN3 Nov like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.4 2.1 2.7e+03 8 13 .. 607 612 .. 604 613 .. 0.87 2 ? -2.0 0.0 4.9 6.2e+03 23 35 .. 681 693 .. 677 696 .. 0.78 3 ! 15.1 6.0 2.4e-05 0.03 6 44 .] 740 787 .. 736 787 .. 0.71 4 ! 16.7 1.0 7.2e-06 0.0093 7 21 .. 1194 1208 .. 1189 1227 .. 0.87 5 ? 5.0 10.6 0.032 41 5 25 .. 1252 1272 .. 1245 1303 .. 0.77 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 2.1 TSP1_CCN 8 WsaCSk 13 Ws+CS+ FUN_001338-T1 607 WSSCSR 612 *****7 PP == domain 2 score: -2.0 bits; conditional E-value: 4.9 TSP1_CCN 23 vsndneeCkleke 35 vs +n+ C++++e FUN_001338-T1 681 VSLNNRFCQTKSE 693 4668999999988 PP == domain 3 score: 15.1 bits; conditional E-value: 2.4e-05 TSP1_CCN 6 teWsaCSktCGlGvstRvsn........dneeCkle.ketrlCqlrpC 44 te saCS++CG+Gv +R+++ d ++C+ + + lC+++ C FUN_001338-T1 740 TELSACSRSCGVGVHYRTRKcnnpvpqnDGRQCEGKdIKFELCNVKDC 787 56699************9865556665566777754145677777777 PP == domain 4 score: 16.7 bits; conditional E-value: 7.2e-06 TSP1_CCN 7 eWsaCSktCGlGvst 21 +Ws+CSktCG G+ t FUN_001338-T1 1194 KWSDCSKTCGEGIRT 1208 8***********976 PP == domain 5 score: 5.0 bits; conditional E-value: 0.032 TSP1_CCN 5 steWsaCSktCGlGvstRvsn 25 ++Ws+CS+ C G tR+++ FUN_001338-T1 1252 VSQWSKCSSPCNGGNQTRTTE 1272 589***************985 PP >> Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 3.8e-05 0.048 137 165 .. 555 585 .. 540 597 .. 0.77 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.8e-05 Reprolysin_4 137 erdey..ditfAHEiGHqfGaaHdkeseseg 165 e d + ++AHE GH++G+ Hd ++ + FUN_001338-T1 555 EEDGFtsAFIIAHETGHTLGMEHDGVNNNCS 585 55655433358*************8766654 PP >> Peptidase_M10 Matrixin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 7.6e-05 0.098 103 129 .. 556 582 .. 508 603 .. 0.80 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 7.6e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 103 eegvdlflvavHeiGHaLGLeHssdee 129 e+g+ + +He GH+LG+eH +++ FUN_001338-T1 556 EDGFTSAFIIAHETGHTLGMEHDGVNN 582 7788888999************76554 PP >> Adt-1 Adt-1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 5.7 7.1e-05 0.091 30 73 .. 666 716 .. 648 719 .. 0.75 2 ? 8.0 1.7 0.0039 4.9 27 75 .. 997 1046 .. 989 1047 .. 0.75 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 7.1e-05 Adt-1 30 eqraCk.vwCdvk.....gsenirtvgn.lpdGtpCgkdkyClkGeClkls 73 ++++Ck +wC +++ ++t+++ +Gt Cg++k+C G+C++++ FUN_001338-T1 666 KRDPCKqLWCIRLsyvslNNRFCQTKSEpALEGTQCGQNKWCRLGKCVPMN 716 67899878**6544655555666666443779***************9987 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0039 Adt-1 27 lqfeqraCkvwCdvkgsenirtvgnlpdGtpCgkd....kyClkGeClklscd 75 q + ++C+ +C+ +++ + ++ +Gt C + C+ G+C + cd FUN_001338-T1 997 NQIPLNPCQQFCQASSN--V-AQVEVENGTACHDSlrsfDVCILGQCQVVGCD 1046 5667799*****99866..3.3346889****876443356***********8 PP >> DUF4953 Met-zincin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.2 0.00012 0.15 15 30 .. 563 578 .. 558 586 .. 0.92 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00012 DUF4953 15 fvsaHEVGHtLGLrhN 30 f++aHE GHtLG++h+ FUN_001338-T1 563 FIIAHETGHTLGMEHD 578 89*************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1573 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 837 (0.0327657); expected 510.9 (0.02) Passed bias filter: 507 (0.0198473); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.50u 0.41s 00:00:00.90 Elapsed: 00:00:00.42 # Mc/sec: 15154.24 // Query: FUN_001338-T2 [L=1479] Description: FUN_001338 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-77 259.1 0.0 5.3e-38 130.8 0.1 2.4 2 MAM MAM domain, meprin/A5/mu 9.6e-23 80.7 77.5 4e-09 37.1 5.4 7.0 4 TSP1_ADAMTS Thrombospondin type 1 domain 2.5e-19 69.9 8.2 2.5e-19 69.9 8.2 5.7 3 ADAMTS_CR_2 ADAMTS cysteine-rich domain 2 1.4e-15 58.3 0.0 2.7e-15 57.4 0.0 1.5 1 Reprolysin Reprolysin (M12B) family zinc metalloproteas 2.3e-13 50.4 0.1 2.6e-05 24.6 0.0 2.5 2 VHL VHL beta domain 5.2e-13 49.5 16.0 1.1e-11 45.2 5.9 7.1 6 TSP_1 Thrombospondin type 1 domain 2.3e-10 41.5 0.0 6.2e-10 40.1 0.0 1.8 1 Reprolysin_5 Metallo-peptidase family M12 1.3e-09 38.8 0.0 2.7e-09 37.8 0.0 1.6 1 ADAMTS_spacer1 ADAM-TS Spacer 1 8.7e-07 30.0 0.0 1.5e-06 29.2 0.0 1.4 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-lik 1.7e-06 28.5 0.0 5.4e-06 26.9 0.0 1.8 1 Reprolysin_2 Metallo-peptidase family M12B Reprolysin-lik 2e-06 28.5 16.2 2.3e-06 28.3 7.4 8.0 6 TSP1_spondin Spondin-like TSP1 domain 7e-06 26.5 6.9 2.4e-05 24.8 6.9 1.9 1 ADAMTS_CR_3 ADAMTS cysteine-rich domain 3.7e-05 24.8 9.3 0.00021 22.4 9.3 2.5 1 PLAC PLAC (protease and lacunin) domain 0.0014 18.9 10.2 0.0072 16.7 10.2 2.3 1 ADAMTS_C ADAMTS C-terminal helical domain 0.0087 16.8 1.0 0.0087 16.8 1.0 8.5 5 TSP1_CCN CCN3 Nov like TSP1 domain ------ inclusion threshold ------ 0.019 16.1 0.1 0.04 15.0 0.1 1.6 1 Pep_M12B_propep Reprolysin family propeptide 0.021 14.9 0.1 0.045 13.8 0.1 1.4 1 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-lik 0.044 14.1 0.0 0.091 13.1 0.0 1.4 1 Peptidase_M10 Matrixin 0.055 14.3 18.8 0.085 13.7 5.7 3.3 2 Adt-1 Adt-1-like domain 0.087 12.5 0.2 0.14 11.9 0.2 1.2 1 DUF4953 Met-zincin Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 125.9 0.0 1.4e-39 1.7e-36 1 157 [. 736 891 .. 736 892 .. 0.94 2 ! 130.8 0.1 4.2e-41 5.3e-38 1 158 [] 1274 1431 .. 1274 1431 .. 0.94 Alignments for each domain: == domain 1 score: 125.9 bits; conditional E-value: 1.4e-39 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgss..kgtlrv 91 CdFe+g lCgwt+d +dd dW+r+++ ++ tgps dht+ + Ghy++lets+ +g +arL+s+ + + Cl+Fwyh +g + g+l++ FUN_001338-T2 736 CDFENG-LCGWTNDRQDDYDWRRHRGRtpTAGTGPSVDHTKGKLGHYVFLETSRPiGPGWKARLVSKYVGMRVA--CLKFWYHAFGGNihMGELQL 828 ******.*****************9999**************************99************999866..*********87733677777 PP MAM 92 llreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 ++++ +e ++ ws+++++g++W vt+ + +++++++f+++rg+g+ +d+ lDdisl++++C FUN_001338-T2 829 RIKTDVGE--NVAWSVNKNRGNRWVLKYVTIFS-KRPYRIIFQGIRGDGYLSDFGLDDISLENNPC 891 77777777..***********************.******************************** PP == domain 2 score: 130.8 bits; conditional E-value: 4.2e-41 MAM 1 CdFeegslCgw...tqdesddadWervsaa..sektgpssdht.etgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskg 87 C+Fe g +C+w ++++ d++dW+ ++++ s++tgps+dht +t+ G y ++e+s+ +++++arL+sp+l+a++ C++Fwyhm+g + g FUN_001338-T2 1274 CTFEAG-FCHWknmRNSQLDQFDWTLRNGStpSRNTGPSNDHTlGTSRGVYAYIEASEPqQRNDRARLISPVLKARRA--CIDFWYHMYGAHTG 1364 ******.***955345666777*****9999**************************9989999***********988..************** PP MAM 88 tlrvllreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeCk 158 lrv+ ++++e+ lw g+q+++W++a++ + + ++q++fe++rg+g ++dialDdi++++g+C+ FUN_001338-T2 1365 WLRVMSKRTTEQ---RLWFKLGNQKNEWHNARLYIFS-YVPYQIIFEGTRGRGFASDIALDDIKITSGRCP 1431 ******999999...99999*****************.********************************6 PP >> TSP1_ADAMTS Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 7.5 1.6e-05 0.02 5 55 .] 647 693 .. 642 693 .. 0.90 2 ! 37.1 5.4 3.1e-12 4e-09 1 55 [] 1096 1151 .. 1096 1151 .. 0.92 3 ! 33.8 10.1 3.2e-11 4.1e-08 1 55 [] 1156 1209 .. 1156 1209 .. 0.98 4 ! 29.9 8.5 5.6e-10 7.2e-07 1 55 [] 1213 1264 .. 1213 1264 .. 0.98 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.6e-05 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 + s Cs++CG Gv +R+ +C + + ++ ++C+ k +++ Cn k+C FUN_001338-T2 647 ELSACSRSCGVGVHYRTRKCNNPVPQ--NDGRQCE--GKDIKFELCNVKDC 693 5579*******************999..579****..8999********99 PP == domain 2 score: 37.1 bits; conditional E-value: 3.1e-12 TSP1_ADAMTS 1 WkagkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkP.setqsCnlkpC 55 W+ kWs+CsktCG+G++t +C+++++++++++++C + +kP ++ + Cnl +C FUN_001338-T2 1096 WSHFKWSDCSKTCGEGIRTELFKCIEQDNNTEVEEHHCYSINKPaPRNKFCNLTAC 1151 88889*************************999*******7777356788****99 PP == domain 3 score: 33.8 bits; conditional E-value: 3.2e-11 TSP1_ADAMTS 1 WkagkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 W + +Ws+Cs +C gG qtR+ C+ + ++++s Cs + +P+++q+Cn ++C FUN_001338-T2 1156 WIVSQWSKCSSPCNGGNQTRTTECRGLLTGVKVNSSLCS-RVRPKTKQECNVHSC 1209 999**************************9999******.*************** PP == domain 4 score: 29.9 bits; conditional E-value: 5.6e-10 TSP1_ADAMTS 1 WkagkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 W +g+Ws+C +tCG+ q+R+v C++ g+ + +C + kP++++ C++kpC FUN_001338-T2 1213 WIVGNWSKCRTTCGSWPQYRSVWCRNILGE---LSLNCPRDVKPPSRRICRNKPC 1264 99*************************999...689******************* PP >> ADAMTS_CR_2 ADAMTS cysteine-rich domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.9 8.2 2e-22 2.5e-19 1 69 [] 547 619 .. 547 619 .. 0.91 2 ? 0.2 0.5 1.1 1.5e+03 31 68 .. 911 946 .. 898 947 .. 0.70 3 ? 0.3 0.8 1.1 1.4e+03 11 39 .. 1236 1268 .. 1232 1284 .. 0.78 Alignments for each domain: == domain 1 score: 69.9 bits; conditional E-value: 2e-22 ADAMTS_CR_2 1 PGqlysadeQCrlifgpeskkcpkkeesvCkklwCskpek....ekecktkeapaadgTsCgekkwClkgkCv 69 PGqly++d+QC+ fg++s++c+ ++ + Ck+lwC + + ++ c+tk++pa++gT+Cg++kwC+ gkCv FUN_001338-T2 547 PGQLYTIDAQCQREFGSNSRFCRGMKRDPCKQLWCIRLSYvslnNRFCQTKSEPALEGTQCGQNKWCRLGKCV 619 9************************9*********764322223899*************************8 PP == domain 2 score: 0.2 bits; conditional E-value: 1.1 ADAMTS_CR_2 31 kklwCskpekekecktkeapaadgTsCgekk....wClkgkC 68 ++ +C+ +++ ++ ++ +gT C + +C+ g+C FUN_001338-T2 911 QQ-FCQASSN-----VAQVEVENGTACHDSLrsfdVCILGQC 946 44.4665443.....467888999999976434449999999 PP == domain 3 score: 0.3 bits; conditional E-value: 1.1 ADAMTS_CR_2 11 Crlifgpeskkcpkk.e...esvCkklwCskpe 39 Cr i g+ s +cp+ + ++C++ C+ + FUN_001338-T2 1236 CRNILGELSLNCPRDvKppsRRICRNKPCEGEI 1268 99999********88667778999998888754 PP >> Reprolysin Reprolysin (M12B) family zinc metalloprotease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.4 0.0 2.1e-18 2.7e-15 1 199 [. 334 534 .. 334 535 .. 0.85 Alignments for each domain: == domain 1 score: 57.4 bits; conditional E-value: 2.1e-18 Reprolysin 1 kYvelfivvdkqlfkklgsdtekvrqkvlevvnlvnsiyke..lnirvvLvglEiW...tdedkievskdaeetLeeflkwreeklk.....krkk 86 kY+e++ +d+++ k +g +ek ++ +l ++n+v +y++ + + v v + + +d +i+++ ++ L+ w ++++k ++ FUN_001338-T2 334 KYIEVMATADSSVIKFHG--KEKSEKYILTLMNIVSRLYQHksIGTPVYFVVVKLVlleNDPKEIKINGKPMPSLSSVCYWGHKTRKgfdssTKDF 427 8*****************..567789*************9766888887666665411156678*****************999876333324666 PP Reprolysin 87 hdaaqLlsgkefeaktvglayvgglCskeksgavnedkkknlealavilaheLghnlGlqhdeekkeCkCeekgvCimneeagsssgv.kFskcsl 181 +d+++++++k+f +g a v+g+C +++s+++ne+ + a i+ahe gh lG++hd +++C+ + ++ im + + s + + +s+cs+ FUN_001338-T2 428 YDQTVFITRKDFGP--SGYAPVHGMCWRTRSCTLNEED---GFTSAFIIAHETGHTLGMEHDGVNNNCSNDVIKGSIMAPLVRSRFDRfYWSSCSR 518 89**********99..9*****************9987...778899**********************999********99999999899***** PP Reprolysin 182 edfekflkkqkgaCLlnk 199 +d+ + l+ CL + FUN_001338-T2 519 RDLISKLR--ALWCLNDV 534 99876554..45566665 PP >> VHL VHL beta domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.0 5.7e-08 7.2e-05 7 76 .. 133 201 .. 128 207 .. 0.90 2 ! 24.6 0.0 2e-08 2.6e-05 6 78 .. 230 301 .. 227 305 .. 0.92 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 5.7e-08 VHL 7 rvaaqvifcnrsPrvvkpvWidfeGePrpyvelkPgtGrrittylghlWlfrdaesddgllvnqkelflp 76 ++a v+f n + r vk+ +i +G + l+ + + ++t+ h W+ rd ++ l++n++ f + FUN_001338-T2 133 TESAYVLFVNSAGRAVKLYYI-VDGTETLFRVLEDRATKSVNTFTVHGWIARDYDTGKQLVINRERTFYA 201 56788************9999.69***************************************9988865 PP == domain 2 score: 24.6 bits; conditional E-value: 2e-08 VHL 6 srvaaqvifcnrsPrvvkpvWidfeGePrpyvelkPgtGrrittylghlWlfrdaesddgllvnqkelflpsa 78 s+ +++ f nrs r vk+ +i+ Ge +++l P ++ty h W+ +d ++ l vn+++ + p++ FUN_001338-T2 230 SQPNSHLSFINRSNRFVKLYYIE-AGETIFFHNLPPHDVILVNTYTSHRWFAKDLDTLKVLHVNGQNQYAPEE 301 56677889**************9.7*****************************************9998875 PP >> TSP_1 Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.2 5.9 8.4e-15 1.1e-11 1 49 [] 643 693 .. 643 693 .. 0.98 2 ? -2.3 1.3 5.8 7.4e+03 13 49 .] 914 946 .. 903 946 .. 0.65 3 ! 19.5 2.4 9e-07 0.0011 5 27 .. 1100 1122 .. 1096 1151 .. 0.75 4 ! 12.4 9.2 0.00015 0.19 4 49 .] 1159 1209 .. 1157 1209 .. 0.76 5 ! 12.4 6.5 0.00015 0.19 4 49 .] 1216 1264 .. 1214 1264 .. 0.95 6 ? -1.9 0.5 4.6 5.8e+03 24 44 .. 1430 1448 .. 1425 1452 .. 0.76 Alignments for each domain: == domain 1 score: 45.2 bits; conditional E-value: 8.4e-15 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 s w+e s+Cs +Cg G+ R+R c++p q++g +C+g+++++e C+ k C FUN_001338-T2 643 SSWTELSACSRSCGVGVHYRTRKCNNPvpQNDGRQCEGKDIKFELCNVKDC 693 78**********************************************999 PP == domain 2 score: -2.3 bits; conditional E-value: 5.8 TSP_1 13 CgkGirvRqRtckspqkggepCtgeaqeteaCkmkkC 49 C + v q + +g++C + + +++C +C FUN_001338-T2 914 CQASSNVAQVEVE----NGTACHDSLRSFDVCILGQC 946 5555544444444....58999999999999966555 PP == domain 3 score: 19.5 bits; conditional E-value: 9e-07 TSP_1 5 eWspCsvTCgkGirvRqRtcksp 27 +Ws+Cs+TCg+Gir++ c + FUN_001338-T2 1100 KWSDCSKTCGEGIRTELFKCIEQ 1122 6*************998777666 PP == domain 4 score: 12.4 bits; conditional E-value: 0.00015 TSP_1 4 seWspCsvTCgkGirvRqRtcksp....qkggepCtgeaqe.teaCkmkkC 49 s+Ws+Cs +C G ++R+ c + + +++ C+ + + C+ + C FUN_001338-T2 1159 SQWSKCSSPCNGGNQTRTTECRGLltgvKVNSSLCSRVRPKtKQECNVHSC 1209 89*******************998777666666776543332567777777 PP == domain 5 score: 12.4 bits; conditional E-value: 0.00015 TSP_1 4 seWspCsvTCgkGirvRqRtcksp.qkggepCtgeaqe..teaCkmkkC 49 + Ws+C +TCg+ + R+ c + + + +C+ ++++ ++C++k+C FUN_001338-T2 1216 GNWSKCRTTCGSWPQYRSVWCRNIlGELSLNCPRDVKPpsRRICRNKPC 1264 68********************99999999******98889*******9 PP == domain 6 score: -1.9 bits; conditional E-value: 4.6 TSP_1 24 ckspqkggepCtgeaqeteaC 44 c ++q ++ +C g+++ + C FUN_001338-T2 1430 CPKKQPNQDQCRGDKS--RYC 1448 7777789999999985..466 PP >> Reprolysin_5 Metallo-peptidase family M12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.1 0.0 4.8e-13 6.2e-10 3 194 .. 334 511 .. 332 512 .. 0.78 Alignments for each domain: == domain 1 score: 40.1 bits; conditional E-value: 4.8e-13 Reprolysin_5 3 rkvallvaaDcsyvaafggdaaqaniinmvntasnvyeref...nislglanltisdstdpetase....asssgnssdlLnefqsssawrgtqsd 91 + + +++ aD s + +g ++ +++i++++n +s++y++++ + +++++l+ ++++ +e + + + s +++ ++ ++ + ++++ FUN_001338-T2 334 KYIEVMATADSSVIKFHGKEKSEKYILTLMNIVSRLYQHKSigtPVYFVVVKLVLLENDPKEIKINgkpmP-SLSSVCYWGHKTRKGFDSSTKDFY 428 6688999**********7799********************999999******999998887655566532.223333333343344444556777 PP Reprolysin_5 92 dlavltlmtncstgvglAwlgqlcnsgsagsvsesveksnsvvvstatewqvfaHEiGHnfGavHDcdsstassqcCplsastcdaggryiMnpss 187 d v+++ ++++ g+A + ++c+ + + ++e + t++ ++aHE+GH++G +HD ++ C+ +d iM+p + FUN_001338-T2 429 DQTVFITRKDFGPS-GYAPVHGMCWRTRSCTLNEE---------DGFTSAFIIAHETGHTLGMEHDGVNN-----NCS-----NDVIKGSIMAPLV 504 778888888*****.**********9998888888.........4568999****************953.....553.....4677888999888 PP Reprolysin_5 188 spnitaf 194 ++ ++f FUN_001338-T2 505 RSRFDRF 511 8777776 PP >> ADAMTS_spacer1 ADAM-TS Spacer 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.8 0.0 2.1e-12 2.7e-09 11 115 .] 986 1087 .. 976 1087 .. 0.86 Alignments for each domain: == domain 1 score: 37.8 bits; conditional E-value: 2.1e-12 ADAMTS_spacer1 11 akgYvtvvtiPagatsikvrerkpsfthLAvkn.vqgkyilngkgsislsstelsllgtvleYrrslpalEeleasgPlqeeleiqvlrqygk 102 +++ t+++ P gat+i ++++p+ L+ + ++ + + + +s t ++++g +++Yrr + ++E ++a gP+++++ ++v + g FUN_001338-T2 986 KEDLQTLLECPVGATNIMLKDSSPNDLILVAMGeKKPRIDVTDEKLVS---TAYEFAGSKFTYRR-EGDKEAITALGPIKDKIMVKVRMGDGG 1074 6667899******************98887775355566677777766...**************.************************999 PP ADAMTS_spacer1 103 atnpdikYeYfip 115 at +++Y+++ p FUN_001338-T2 1075 ATPVNLQYQFYKP 1087 **********965 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.0 1.2e-09 1.5e-06 2 123 .] 357 484 .. 356 484 .. 0.83 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 1.2e-09 Reprolysin_3 2 ariaslveaanqvye.relg..irlqlaaiiitssa.dtpyttkdaleildeaaevist......ergqsgydlvhlftkrdvsgvgGlAyvgavc 87 ++i +l++ ++ y+ + +g + + +++++ ++ + ++ + ++++ l++ + ++ ++ ++ yd +++t++d+ g G A v ++c FUN_001338-T2 357 KYILTLMNIVSRLYQhKSIGtpVYFVVVKLVLLENDpKEIKINGKPMPSLSSVCYWGHKtrkgfdSSTKDFYDQTVFITRKDF-GPSGYAPVHGMC 451 589999*********77777999999998887766514666666667777777666666777886578999***********9.************ PP Reprolysin_3 88 nsskkfglnsgssplgdtgadtfaHEiGHnfGanHt 123 +++ ln+++ g t+a +aHE GH +G +H+ FUN_001338-T2 452 WRTRSCTLNEED---GFTSAFIIAHETGHTLGMEHD 484 *********999...57789***************8 PP >> Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.0 4.2e-09 5.4e-06 5 188 .. 356 520 .. 353 526 .. 0.70 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 4.2e-09 Reprolysin_2 5 teelvevlnrvnqiYeeddieislglrneaeieattsasdsgnn......rcnssttevrrlnllsqlegekdydlahlvllgefsggvlGLAyvg 94 + +++++n v+++Y++ i++ + ++ ++ + + + ++ + n +++ + + + ++ + yd +++++ ++f g G A v FUN_001338-T2 356 EKYILTLMNIVSRLYQHKSIGTPVYFVVVKLVLLENDPKEIKINgkpmpsLSSVCYWGHKTRKGFDSSTK-DFYDQTVFITRKDF--GPSGYAPVH 448 67899*********************97666666666666666655555533444554444666665443.56788888877777..567****** PP Reprolysin_2 95 qicqkkassrktntglsttanygsaveesqeidvvaHEvGHnFGatHdndgsssasegceenaatsaesangkfiMapa..sksnntqFSpcsisl 188 ++c ++ s+ t +n ++ ++ ++aHE GH+ G Hd + ++s+ + +iMap s + +S cs+ FUN_001338-T2 449 GMCWRTRSC----T-----LNEEDGF---TSAFIIAHETGHTLGMEHDGVNN-NCSN-----------DVIKGSIMAPLvrSRFDRFYWSSCSRRD 520 *********....4.....6666666...4899***************8744.4442...........2233468887744445555557787765 PP >> TSP1_spondin Spondin-like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 7.4 1.8e-09 2.3e-06 4 52 .] 643 693 .. 641 693 .. 0.93 2 ? -1.5 1.5 3.4 4.4e+03 12 52 .] 910 946 .. 907 946 .. 0.72 3 ! 15.2 1.4 2.2e-05 0.028 8 33 .. 1100 1125 .. 1094 1148 .. 0.79 4 ! 14.4 11.8 3.9e-05 0.049 1 52 [] 1151 1209 .. 1151 1209 .. 0.91 5 ? 4.3 8.0 0.055 70 7 52 .] 1216 1264 .. 1212 1264 .. 0.79 6 ? -0.2 0.7 1.4 1.8e+03 37 50 .. 1429 1443 .. 1424 1445 .. 0.86 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 1.8e-09 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRevive.pqnggkpCpell.errkCneepC 52 s+W+e s Cs++Cg Gv++RtR+ + pqn+g++C + + + Cn + C FUN_001338-T2 643 SSWTELSACSRSCGVGVHYRTRKCNNPvPQNDGRQCEGKDiKFELCNVKDC 693 889999******************76549***********9********99 PP == domain 2 score: -1.5 bits; conditional E-value: 3.4 TSP1_spondin 12 CsktCgkGvqtRtRevivepqnggkpCpell.errkCneepC 52 C++ C+ ++ +v + + ++g +C ++l C +C FUN_001338-T2 910 CQQFCQASS-----NVAQVEVENGTACHDSLrSFDVCILGQC 946 555554444.....4556666999999999988899988888 PP == domain 3 score: 15.2 bits; conditional E-value: 2.2e-05 TSP1_spondin 8 eWseCsktCgkGvqtRtRevivepqn 33 +Ws+CsktCg+G++t + i +++n FUN_001338-T2 1100 KWSDCSKTCGEGIRTELFKCIEQDNN 1125 7************9976666555555 PP == domain 4 score: 14.4 bits; conditional E-value: 3.9e-05 TSP1_spondin 1 CvvseW..seWseCsktCgkGvqtRt...RevivepqnggkpCpell..errkCneepC 52 C++ eW s+Ws+Cs+ C++G qtRt R +++ + + + C + +++Cn ++C FUN_001338-T2 1151 CEIYEWivSQWSKCSSPCNGGNQTRTtecRGLLTGVKVNSSLCSRVRpkTKQECNVHSC 1209 999999889****************9666778999*********999889999****99 PP == domain 5 score: 4.3 bits; conditional E-value: 0.055 TSP1_spondin 7 seWseCsktCgkGvqtRtRevivepqnggkpCpell...errkCneepC 52 ++Ws+C +tCg+ q+R+ + +Cp++ rr C+++pC FUN_001338-T2 1216 GNWSKCRTTCGSWPQYRSVWCRNILGELSLNCPRDVkppSRRICRNKPC 1264 58********888888775444445566788999887888999999999 PP == domain 6 score: -0.2 bits; conditional E-value: 1.4 TSP1_spondin 37 pCpell.errkCnee 50 +Cp+++ ++ +C+++ FUN_001338-T2 1429 RCPKKQpNQDQCRGD 1443 7***********876 PP >> ADAMTS_CR_3 ADAMTS cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 6.9 1.8e-08 2.4e-05 78 115 .] 937 974 .. 911 974 .. 0.89 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.8e-08 ADAMTS_CR_3 78 tlslcvsgscrtfgcdgrmdsqqvwdrcqvcggdnstc 115 ++ +c+ g c+++gcdg m s++ drc vcgg + tc FUN_001338-T2 937 SFDVCILGQCQVVGCDGVMGSNKTLDRCGVCGGKDDTC 974 4579********************************99 PP >> PLAC PLAC (protease and lacunin) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 9.3 1.6e-07 0.00021 3 30 .. 1443 1470 .. 1440 1471 .. 0.94 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.6e-07 PLAC 3 DkfanCelVvqarlCshkyYrkfCCkSC 30 Dk+++C+++vq++ C k +++CCk+C FUN_001338-T2 1443 DKSRYCRVAVQLNWCLSKRWSQACCKTC 1470 88************************** PP >> ADAMTS_C ADAMTS C-terminal helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 10.2 5.6e-06 0.0072 5 41 .. 1439 1474 .. 1438 1477 .. 0.91 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 5.6e-06 ADAMTS_C 5 kCvgDrWtvyCrViReknLCQDmRWyQrccetcrdiy 41 +C gD+ + yCrV + n C +RW Q cc+tc+ ++ FUN_001338-T2 1439 QCRGDK-SRYCRVAVQLNWCLSKRWSQACCKTCERVT 1474 588887.89************************9876 PP >> TSP1_CCN CCN3 Nov like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.4 2 2.5e+03 8 13 .. 513 518 .. 510 519 .. 0.87 2 ? -1.9 0.0 4.6 5.9e+03 23 35 .. 587 599 .. 583 602 .. 0.78 3 ! 15.1 6.0 2.2e-05 0.028 6 44 .] 646 693 .. 642 693 .. 0.71 4 ! 16.8 1.0 6.8e-06 0.0087 7 21 .. 1100 1114 .. 1095 1133 .. 0.87 5 ? 4.9 10.8 0.035 45 5 25 .. 1158 1178 .. 1151 1209 .. 0.77 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 2 TSP1_CCN 8 WsaCSk 13 Ws+CS+ FUN_001338-T2 513 WSSCSR 518 *****7 PP == domain 2 score: -1.9 bits; conditional E-value: 4.6 TSP1_CCN 23 vsndneeCkleke 35 vs +n+ C++++e FUN_001338-T2 587 VSLNNRFCQTKSE 599 4668999999988 PP == domain 3 score: 15.1 bits; conditional E-value: 2.2e-05 TSP1_CCN 6 teWsaCSktCGlGvstRvsn........dneeCkle.ketrlCqlrpC 44 te saCS++CG+Gv +R+++ d ++C+ + + lC+++ C FUN_001338-T2 646 TELSACSRSCGVGVHYRTRKcnnpvpqnDGRQCEGKdIKFELCNVKDC 693 56699************9865556665566777754145677777777 PP == domain 4 score: 16.8 bits; conditional E-value: 6.8e-06 TSP1_CCN 7 eWsaCSktCGlGvst 21 +Ws+CSktCG G+ t FUN_001338-T2 1100 KWSDCSKTCGEGIRT 1114 8***********976 PP == domain 5 score: 4.9 bits; conditional E-value: 0.035 TSP1_CCN 5 steWsaCSktCGlGvstRvsn 25 ++Ws+CS+ C G tR+++ FUN_001338-T2 1158 VSQWSKCSSPCNGGNQTRTTE 1178 589***************985 PP >> Pep_M12B_propep Reprolysin family propeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.1 3.2e-05 0.04 53 91 .. 3 39 .. 1 41 [. 0.85 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 3.2e-05 Pep_M12B_propep 53 LeknrellapgftvetygkdgeevtespqeeehChYqGh 91 L++n++l++++ftve ++++g+ +t+ + +e+C+ +G+ FUN_001338-T2 3 LKLNTKLFGSSFTVERHKENGSIETK--TVTEQCYLVGE 39 999************99999987776..45589****97 PP >> Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.1 3.5e-05 0.045 137 165 .. 461 491 .. 446 503 .. 0.77 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 3.5e-05 Reprolysin_4 137 erdey..ditfAHEiGHqfGaaHdkeseseg 165 e d + ++AHE GH++G+ Hd ++ + FUN_001338-T2 461 EEDGFtsAFIIAHETGHTLGMEHDGVNNNCS 491 55655433358*************8766654 PP >> Peptidase_M10 Matrixin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 7.1e-05 0.091 103 129 .. 462 488 .. 414 509 .. 0.80 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 7.1e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 103 eegvdlflvavHeiGHaLGLeHssdee 129 e+g+ + +He GH+LG+eH +++ FUN_001338-T2 462 EDGFTSAFIIAHETGHTLGMEHDGVNN 488 7788888999************76554 PP >> Adt-1 Adt-1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 5.7 6.6e-05 0.085 30 73 .. 572 622 .. 554 625 .. 0.75 2 ? 8.1 1.7 0.0036 4.6 27 75 .. 903 952 .. 895 953 .. 0.75 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 6.6e-05 Adt-1 30 eqraCk.vwCdvk.....gsenirtvgn.lpdGtpCgkdkyClkGeClkls 73 ++++Ck +wC +++ ++t+++ +Gt Cg++k+C G+C++++ FUN_001338-T2 572 KRDPCKqLWCIRLsyvslNNRFCQTKSEpALEGTQCGQNKWCRLGKCVPMN 622 67899878**6544655555666666443779***************9987 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0036 Adt-1 27 lqfeqraCkvwCdvkgsenirtvgnlpdGtpCgkd....kyClkGeClklscd 75 q + ++C+ +C+ +++ + ++ +Gt C + C+ G+C + cd FUN_001338-T2 903 NQIPLNPCQQFCQASSN--V-AQVEVENGTACHDSlrsfDVCILGQCQVVGCD 952 5667799*****99866..3.3346889****876443356***********8 PP >> DUF4953 Met-zincin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.2 0.00011 0.14 15 30 .. 469 484 .. 464 492 .. 0.92 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00011 DUF4953 15 fvsaHEVGHtLGLrhN 30 f++aHE GHtLG++h+ FUN_001338-T2 469 FIIAHETGHTLGMEHD 484 89*************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1479 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 731 (0.0286162); expected 510.9 (0.02) Passed bias filter: 426 (0.0166765); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.48u 0.40s 00:00:00.88 Elapsed: 00:00:00.42 # Mc/sec: 14063.15 // Query: FUN_001339-T1 [L=113] Description: FUN_001339 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 13.0 0.0 0.19 12.6 0.0 1.1 1 Ras_bdg_2 Ras-binding domain of Byr2 Domain annotation for each model (and alignments): >> Ras_bdg_2 Ras-binding domain of Byr2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 7.3e-06 0.19 20 93 .. 11 87 .. 2 92 .. 0.77 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.3e-06 Ras_bdg_2 20 fnaeeikrkvlkklglkekeaenydvYvldgkdkeslrlLsdvELvtic...hspdrleknrliLrkkaeePseeal 93 + + + + +k +l+++ +ny +++ ++ +e+ L + Lv+ + +d++ + ++L+ ++ +P e++ FUN_001339-T1 11 KGGLAMMTAAARKTSLENQYLRNYYIFFSFDNVEETDTKLKELSLVSRLagrTTEDDPSRCIILLCYNQRYPVESQT 87 45667899999**************9999998888888888888886551113445588888889999999987765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 507 (0.0198473); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.21u 0.43s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1154.93 // Query: FUN_001340-T1 [L=100] Description: FUN_001340 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.022 15.1 0.1 0.022 15.1 0.1 1.2 1 SNaCT12 Short NACHT-associated C-Terminal domain, family 12 0.45 9.6 1.6 7.8 5.5 0.0 1.9 2 ATG22 Vacuole effluxer Atg22 like Domain annotation for each model (and alignments): >> SNaCT12 Short NACHT-associated C-Terminal domain, family 12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.1 1.7e-06 0.022 3 53 .. 2 52 .. 1 90 [. 0.87 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.7e-06 SNaCT12 3 selieqewiipkiikskdkvesdknetssdfnviskmissvflmdddsvnl 53 s li+ e + k ik k+k + +k++t d+ + s++ + + +d+sv FUN_001340-T1 2 SYLIQSEHLQSKGIKQKEKENNNKKQTNKDLYLKSNVSNAALARNDNSVAN 52 6799********************************999999999999853 PP >> ATG22 Vacuole effluxer Atg22 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.5 0.0026 33 167 199 .. 12 44 .. 2 46 .. 0.78 2 ? 5.5 0.0 0.00061 7.8 47 83 .. 51 86 .. 44 88 .. 0.87 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.0026 ATG22 167 eeleeeeeeeesaeeeeskelklstrisslGlg 199 ++ +++e+e++++++++k+l l++++s+ +l+ FUN_001340-T1 12 SKGIKQKEKENNNKKQTNKDLYLKSNVSNAALA 44 34444568899999***************9875 PP == domain 2 score: 5.5 bits; conditional E-value: 0.00061 ATG22 47 sapCsasgdeqcvvyflgleidtaSfvlytfslsvll 83 ++ Csa++d ++v +f++l+ + +Sf+l+ ++ v++ FUN_001340-T1 51 ANLCSADED-KNVNKFAYLKPKNSSFALFARAFFVFC 86 567*****9.*********************988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2201 (0.0861617); expected 510.9 (0.02) Passed bias filter: 743 (0.0290859); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 990.71 // Query: FUN_001341-T1 [L=147] Description: FUN_001341 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.4e-55 184.9 0.0 8.3e-55 184.7 0.0 1.0 1 UQ_con Ubiquitin-conjugating enzyme 0.0013 19.4 0.0 0.0019 18.9 0.0 1.3 1 RWD RWD domain ------ inclusion threshold ------ 0.044 14.1 0.0 0.072 13.5 0.0 1.3 1 UEV UEV domain 0.12 12.7 0.0 0.27 11.7 0.0 1.6 1 UBC_like Ubiquitin conjugating domain-like Domain annotation for each model (and alignments): >> UQ_con Ubiquitin-conjugating enzyme # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 184.7 0.0 1.3e-58 8.3e-55 1 139 [. 5 141 .. 5 142 .. 0.98 Alignments for each domain: == domain 1 score: 184.7 bits; conditional E-value: 1.3e-58 UQ_con 1 rlqkelkelkkkppsgisakpvddenllewkvtilgpedtpYeggvFklelefpedYPfkpPkvkfttkiyHPnvdesGevcldiLkeekWspalt 96 r++kel++l ++pp+++sa pv d +l++w++ti+gp+d+pY+ggvF l+++fp+dYPfkpPkv+fttkiyHPn++++G++cldiL+++ Wspalt FUN_001341-T1 5 RINKELQDLGRDPPAQCSAGPVGD-DLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVSFTTKIYHPNINSNGSICLDILRSQ-WSPALT 98 899********************8.**************************************************************77.****** PP UQ_con 97 lesvllsiqsLlsepnpesplnaeaaklykknreefekkvkel 139 +++vllsi+sLl++pnp++pl ++a++yk++r+++ ++++e+ FUN_001341-T1 99 ISKVLLSICSLLTDPNPDDPLVPDIARIYKTDRQKYGETAREW 141 ****************************************987 PP >> RWD RWD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.0 2.9e-07 0.0019 51 105 .. 50 107 .. 28 112 .. 0.71 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 2.9e-07 xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxx.xxxxxxxxxx RF RWD 51 lvlevtlpedYPdepPkislsskenls..reqvssllekleelaeen.lgevmifeli 105 + l++++p dYP +pPk+s+++k + +++ s +l+ l+++++ ++ +++ FUN_001341-T1 50 FFLTIHFPTDYPFKPPKVSFTTKIYHPniNSNGSICLDILRSQWSPAlTISKVLLSIC 107 679*******************994442233334466777777766655555555555 PP >> UEV UEV domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 1.1e-05 0.072 53 116 .. 53 111 .. 41 118 .. 0.75 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.1e-05 UEV 53 llwlldsyPveaPivfvkptaemvikknkhvdaeGrvylpyLeeWkseksnlvklvqelaqvfe 116 ++ + +yP+++P v + + + +++++G + l++L++ +s++ +++k++ ++++ + FUN_001341-T1 53 TIHFPTDYPFKPPKVSFTTKIY-----HPNINSNGSICLDILRSQWSPALTISKVLLSICSLLT 111 6788999******987654433.....559************8655558888887776666555 PP >> UBC_like Ubiquitin conjugating domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 4.2e-05 0.27 25 46 .. 52 73 .. 47 93 .. 0.90 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 4.2e-05 UBC_like 25 ltiklpanyPLsavevesekrv 46 lti++p++yP+++++v+ + ++ FUN_001341-T1 52 LTIHFPTDYPFKPPKVSFTTKI 73 99**************998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (147 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 380 (0.0148757); expected 510.9 (0.02) Passed bias filter: 364 (0.0142494); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1489.99 // Query: FUN_001342-T1 [L=767] Description: FUN_001342 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-62 210.5 0.0 4.1e-62 209.8 0.0 1.4 1 SIR2 Sir2 family 0.00026 21.2 0.0 0.12 12.5 0.0 2.3 2 TPP_enzyme_M Thiamine pyrophosphate enzyme, central domain ------ inclusion threshold ------ 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 DUF592 Protein of unknown function (DUF592) 0.083 13.8 0.1 0.2 12.6 0.1 1.6 1 DUF3624 Protein of unknown function (DUF3624) 1.5 9.7 9.1 2.6 8.9 0.8 2.7 2 Opy2 Opy2 protein Domain annotation for each model (and alignments): >> SIR2 Sir2 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 209.8 0.0 8.1e-66 4.1e-62 1 180 [] 183 370 .. 183 370 .. 0.96 Alignments for each domain: == domain 1 score: 209.8 bits; conditional E-value: 8.1e-66 SIR2 1 GAGiStesGipdFRskkdGlyaklakee..laspeavfskkllveePevfyniarellakeaepneaHkflkklekkgkllrliTQNiDgLekkaG 94 GAG+S+++GipdFRs +dG+yakl+ e l +p+a+f+++++ ++P++f ++a+e+++ +++p+ +H+f+k+le+kg+ll+++ QNiD+Le+ aG FUN_001342-T1 183 GAGVSVSCGIPDFRS-RDGVYAKLSLEYpdLPDPQAMFDIEYFSQNPRPFFKFAKEIYPGQFQPSLSHHFIKQLESKGQLLQNYSQNIDTLEQIAG 277 9*************9.********988667****************************************************************** PP SIR2 95 skkvvelHGslakvkCvecekkldaeelkeeieaekvpkcekcgg......llkpdvvfFGealpeklkeale.kleeadlliviGtSlkVap 180 +++v+++HGs+++++C++c+++++ e ++e+i ++ +p+c+kc + ++kpd+vfFGe+lp+++ + l+ + e+adlliviG+SlkV+p FUN_001342-T1 278 ITRVIQCHGSFSTASCTNCKHQVSCEVIREDIFKQIIPRCPKCPQdgscfsIMKPDIVFFGESLPSQFYHNLDnDSEKADLLIVIGSSLKVRP 370 *******************************************99999**9**************665555554*****************98 PP >> TPP_enzyme_M Thiamine pyrophosphate enzyme, central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.3 0.0 0.002 10 1 25 [. 165 189 .. 165 196 .. 0.89 2 ! 12.5 0.0 2.4e-05 0.12 75 137 .] 353 412 .. 335 412 .. 0.83 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.002 TPP_enzyme_M 1 iekaaellkkakrPvilaGggvrrs 25 +++++ell+ +k++v+l G gv+ s FUN_001342-T1 165 LDDVVELLRGSKNIVVLTGAGVSVS 189 5789*****************9865 PP == domain 2 score: 12.5 bits; conditional E-value: 2.4e-05 TPP_enzyme_M 75 leeaDlvlavGarfddirttgklp.efapeakiihididpaeigknykvdlaivgdakevleaL 137 e+aDl++++G++++ r + +p ++pe + +i i+++ + + + d++++gd+ ++++L FUN_001342-T1 353 SEKADLLIVIGSSLKV-RPVALIPsHIPPE--VPQILINREPLRHMR-FDVELLGDCDVIVSEL 412 589***********77.7778777577777..889999999999886.9********9988876 PP >> DUF592 Protein of unknown function (DUF592) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 3.6e-06 0.019 127 153 .] 156 182 .. 140 182 .. 0.88 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.6e-06 DUF592 127 rlrlsnfstidhfvdklkkakkilVlt 153 r++l++++t+d++v+ l+ +k i+Vlt FUN_001342-T1 156 RQKLDHINTLDDVVELLRGSKNIVVLT 182 99************************9 PP >> DUF3624 Protein of unknown function (DUF3624) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 4e-05 0.2 2 31 .. 301 330 .. 300 339 .. 0.89 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4e-05 DUF3624 2 aCneckesvfkqKlGRCkrCmkqltvlsll 31 +C+ +e++fkq + RC +C + + +s++ FUN_001342-T1 301 SCEVIREDIFKQIIPRCPKCPQDGSCFSIM 330 8*******************9998888876 PP >> Opy2 Opy2 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 2.0 0.017 86 6 23 .. 286 305 .. 282 308 .. 0.73 2 ? 8.9 0.8 0.00051 2.6 9 22 .. 315 328 .. 312 331 .. 0.88 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.017 Opy2 6 d..ttpsCPsCpsgeeCvlt 23 +t sC +C+ + +C ++ FUN_001342-T1 286 GsfSTASCTNCKHQVSCEVI 305 44578899999999999765 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00051 Opy2 9 psCPsCpsgeeCvl 22 p CP+Cp++ +C FUN_001342-T1 315 PRCPKCPQDGSCFS 328 89**********76 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (767 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 742 (0.0290468); expected 510.9 (0.02) Passed bias filter: 528 (0.0206694); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.40 # Mc/sec: 7729.80 // Query: FUN_001343-T1 [L=150] Description: FUN_001343 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-08 32.2 1.0 1.2e-07 32.0 1.0 1.0 1 OST3_OST6 OST3 / OST6 family, transporter family Domain annotation for each model (and alignments): >> OST3_OST6 OST3 / OST6 family, transporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.0 1.0 4.6e-12 1.2e-07 180 292 .. 29 146 .. 16 148 .. 0.78 Alignments for each domain: == domain 1 score: 32.0 bits; conditional E-value: 4.6e-12 OST3_OST6 180 sknlwavlslivillftsGymfnqIrgvpyvakdkk....gg.isyfaggsqnQfgiEtqivallygllallvilLiklvpriknkkvqrvlvill 270 s +++ +++li+++l+t+G + I ++p v+++ + + + ++ + Q+++E+ + ++l + +l++i+L + + +k +r+l + l FUN_001343-T1 29 SAMVVFAFVLISYFLVTGGIIYDVIVEPPSVGSTTDefghSKpVAFMPYRVNGQYIMEGLASSFLFSVGGLGFIILD-KSNAVGMSKLNRFLLLSL 123 5688999************************98765221134467777777**************************.677777777777776555 PP OST3_OST6 271 lvvlfllfslllsvf.kiKnpgY 292 +v++l+ + vf ++K pgY FUN_001343-T1 124 GFVCVLVSFFTCRVFmRMKLPGY 146 55555444444455438999999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (150 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 640 (0.0250538); expected 510.9 (0.02) Passed bias filter: 373 (0.0146017); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1538.73 // Query: FUN_001344-T1 [L=321] Description: FUN_001344 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-75 253.3 0.0 3.9e-75 253.1 0.0 1.0 1 Pkinase Protein kinase domain 8e-35 120.9 0.0 1e-34 120.5 0.0 1.1 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 3e-07 30.3 0.1 4.8e-07 29.6 0.1 1.3 1 Haspin_kinase Haspin like kinase domain 0.00017 21.4 0.1 0.0038 16.9 0.0 2.3 2 ABC1 ABC1 atypical kinase-like domain ------ inclusion threshold ------ 0.026 14.5 0.8 0.092 12.6 0.8 1.8 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.037 14.3 0.1 0.095 12.9 0.1 1.6 1 APH Phosphotransferase enzyme family 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 Seadorna_VP7 Seadornavirus VP7 0.085 12.6 0.0 0.14 11.8 0.0 1.5 1 Kinase-like Kinase-like Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 253.1 0.0 1.2e-78 3.9e-75 3 262 .] 17 297 .. 15 297 .. 0.95 Alignments for each domain: == domain 1 score: 253.1 bits; conditional E-value: 1.2e-78 Pkinase 3 vleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdlls.rkgals 96 ++ek+GeG++g+Vyk+++k+++k+vA+Kki+ e a++ ++++rEi++l++l+ hpn+v l ++++++ +lylv+E+++++ l+++l ++ +l+ FUN_001344-T1 17 KIEKIGEGTYGVVYKGRNKKNNKLVALKKIRLELAEEGIPSTAVREISLLRELReHPNVVSLEHILHDDAKLYLVFEFLMCD-LKKHLDsTRDVLD 111 789*****************************************************************************99.55555549999** PP Pkinase 97 eeeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk.ltsfvgtseYmAPEvl.kskkygkkvDvWslGvilyel 190 + +k++l+qi +++ y+Hs++++HrDlKp+N+Lide+g +K++DFGl + + + +t+ ++t +Y+APEvl + ++y+ +vD+Ws+G+i++e+ FUN_001344-T1 112 SMLIKSYLYQITNAMYYCHSRRILHRDLKPQNLLIDEQGLVKLADFGLGRAFGIPVRaYTHEIVTLWYRAPEVLlGCQRYSCPVDIWSIGCIFAEM 207 *****************************************************99999****************999******************* PP Pkinase 191 ltgkppfsaekekekvekeldqlekilki...elkeklpepssi......................seeakdllkkllkkdpkkRltaeellqhpw 261 +t++p+f+ +++ e+dql++i++i ++++++p s++ +e dll+k+l ++p kR++a+ +l+hp+ FUN_001344-T1 208 VTKRPLFH---GDS----EIDQLFRIFRIlgtPTEKNWPGVSQLqdyktdfprwngeglkkavpqmDEVGLDLLEKMLIYNPAKRISAKAALDHPY 296 ********...555....88999999999888889999999999*********************9999*************************** PP Pkinase 262 f 262 f FUN_001344-T1 297 F 297 8 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 120.5 0.0 3.2e-38 1e-34 4 200 .. 18 210 .. 15 226 .. 0.92 Alignments for each domain: == domain 1 score: 120.5 bits; conditional E-value: 3.2e-38 PK_Tyr_Ser-Thr 4 keklGeGafGeVykgtlkeekekkkikVavKtlkeeaseee.keefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrkkk 96 ek+GeG++G Vykg+ k k++ Va+K+++ e ee + ++e++l+++l +hpn+v+l + ++ +l++v+e++ +Lk++L +++ FUN_001344-T1 18 IEKIGEGTYGVVYKGRNK----KNNKLVALKKIRLELAEEGiPSTAVREISLLRELrEHPNVVSLEHILHDDAKLYLVFEFLMC-DLKKHLDSTR 107 689*************99....89999******87766666378899*********9************************975.9********* PP PK_Tyr_Ser-Thr 97 eklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekk.ftsksDvWsf 190 + l+ + ++ +qi ++m y +s++++Hrdl +N L++e+ vk++DfGL r+ ++ +++ + + + apE+l ++ ++ D+Ws FUN_001344-T1 108 DVLDSMLIKSYLYQITNAMYYCHSRRILHRDLKPQNLLIDEQGLVKLADFGLGRAF--GIPVRAYTHEIVTLWYRAPEVLLGCQrYSCPVDIWSI 200 ********************************************************..55667788888999999****998776********** PP PK_Tyr_Ser-Thr 191 GvllwEiftl 200 G + E++t+ FUN_001344-T1 201 GCIFAEMVTK 210 *******994 PP >> Haspin_kinase Haspin like kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.1 1.5e-10 4.8e-07 97 256 .. 10 163 .. 3 184 .. 0.77 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 1.5e-10 Haspin_kinase 97 ieeedlvskkadseklssevyrlke..kdeevvlKvipldvledvtiskelslkelkllklvkGtpglllllwdkllrsepdfydenqlflvlllk 190 ++ ed+ + +e + vy+ ++ +++ v+lK+i l+ e+ + s + + e+ ll+ ++ p+ + l +++l + y fl++ lk FUN_001344-T1 10 MKMEDFIKIEKIGEGTYGVVYKGRNkkNNKLVALKKIRLELAEEGIPS--TAVREISLLRELREHPNVVSL--EHILHDDAKLY-LVFEFLMCDLK 100 455566666667999*******9998789999*******999998888..667777777777766665443..44555553333.35578999999 PP Haspin_kinase 191 kkGkdLehvklkswaqalsifwqivkilyvaEtkfqFEHRdLhldniLvdknlnvtlidyklaRak 256 k+ ++ +v l s+ ++s ++qi++ +y + + HRdL+ +n+L+d+++ v l d+ l+Ra FUN_001344-T1 101 KHLDSTRDV-LDSM-LIKSYLYQITNAMYYCHSR-RILHRDLKPQNLLIDEQGLVKLADFGLGRAF 163 987765444.5555.68999**********9987.678**************************95 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.047 1.5e+02 38 68 .. 21 52 .. 5 69 .. 0.82 2 ! 16.9 0.0 1.2e-06 0.0038 156 230 .. 99 175 .. 85 181 .. 0.72 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.047 ABC1 38 iAaASiaqVhkArlk.dgeeVavKvqrpgvkk 68 i+ + V+k+r k +++ Va+K r ++++ FUN_001344-T1 21 IGEGTYGVVYKGRNKkNNKLVALKKIRLELAE 52 66677799*****9978889****99987765 PP == domain 2 score: 16.9 bits; conditional E-value: 1.2e-06 ABC1 156 iddlealeeagidrkeiaeklvelfleqifed..gffhaDphpGNllvrkdgelvllDfGlmgeldekfrkklaell 230 ++++ + +d+ i + l ++++ + + + +++h D+ p Nll++++g + l DfGl + + r + e++ FUN_001344-T1 99 LKKHLDSTRDVLDSMLIKSYLYQITNAMYYCHsrRILHRDLKPQNLLIDEQGLVKLADFGLGRAFGIPVRAYTHEIV 175 444444445667777777778888887777552267*************************9988777776666555 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.8 2.9e-05 0.092 102 155 .. 96 150 .. 43 177 .. 0.81 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 2.9e-05 Kdo 102 aqdLedllaqwae.laeelrrallkavgrlirklhragvqHgdlyakhillqtek 155 + dL+++l + ++ l+ l + l ++ ++ h++ + H+dl ++++l+++++ FUN_001344-T1 96 MCDLKKHLDSTRDvLDSMLIKSYLYQITNAMYYCHSRRILHRDLKPQNLLIDEQG 150 57999***99999999***********************************9997 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.1 3e-05 0.095 167 187 .. 131 151 .. 62 161 .. 0.75 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 3e-05 APH 167 ppvlvHgDlhpgNllvddggr 187 ++++H+Dl+p Nll+d++g FUN_001344-T1 131 SRRILHRDLKPQNLLIDEQGL 151 5799*************5444 PP >> Seadorna_VP7 Seadornavirus VP7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 3.8e-05 0.12 157 186 .. 129 156 .. 111 159 .. 0.84 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 3.8e-05 Seadorna_VP7 157 lhresggtlhGDvnvenlmcDklGmlklvD 186 h s +lh D +++nl+ D+ G +kl D FUN_001344-T1 129 CH--SRRILHRDLKPQNLLIDEQGLVKLAD 156 34..8899********************99 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 4.5e-05 0.14 153 190 .. 121 158 .. 92 233 .. 0.83 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 4.5e-05 Kinase-like 153 qlirlaasLqskglvhgkfsvdnllldekggvflggfe 190 q+ + + +s ++h +++++nll+de+g v+l +f+ FUN_001344-T1 121 QITNAMYYCHSRRILHRDLKPQNLLIDEQGLVKLADFG 158 66777788899**************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 629 (0.0246232); expected 510.9 (0.02) Passed bias filter: 571 (0.0223527); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.25u 0.44s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3169.04 // Query: FUN_001345-T1 [L=93] Description: FUN_001345 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-10 41.3 0.1 1.7e-10 41.3 0.1 1.9 2 Ribosomal_S18 Ribosomal protein S18 ------ inclusion threshold ------ 0.12 12.8 2.6 0.14 12.5 2.6 1.1 1 RRXRR RRXRR protein 0.12 13.1 0.0 0.14 12.9 0.0 1.2 1 PAS_9 PAS domain 0.29 11.2 1.0 0.41 10.6 1.0 1.2 1 SieB Super-infection exclusion protein B Domain annotation for each model (and alignments): >> Ribosomal_S18 Ribosomal protein S18 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.5 0.35 2.2e+03 22 37 .. 22 37 .. 15 38 .. 0.83 2 ! 41.3 0.1 2.6e-14 1.7e-10 2 32 .. 55 86 .. 54 89 .. 0.94 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.35 Ribosomal_S18 22 kIlprriTglcakqQr 37 k + rr l a+ Qr FUN_001345-T1 22 KLRKRRTDQLRARLQR 37 7788999999999998 PP == domain 2 score: 41.3 bits; conditional E-value: 2.6e-14 Ribosomal_S18 2 keeidYkdvelLsqFi.terGkIlprriTglc 32 +ei+Yk+v+lLsqFi +++G+I++r Tg c FUN_001345-T1 55 DIEINYKNVRLLSQFIsPHTGRIYGRTLTGQC 86 689***************************99 PP >> RRXRR RRXRR protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 2.6 2.2e-05 0.14 87 144 .. 14 70 .. 3 74 .. 0.83 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2.2e-05 RRXRR 87 kkklesRrelRrsRRsrktryrkaRfdnRkrkkgwlaPSlqsrvdttlrvvkrlakla 144 ++le++r+lR+ RR+ ++r r +R d+ r+ g l +++ ++ + v+ l++++ FUN_001345-T1 14 YHHLEKKRKLRK-RRTDQLRARLQRLDEEDRPTGCLLCPMRNDIEINYKNVRLLSQFI 70 567889999986.66889******************9999999999999999888775 PP >> PAS_9 PAS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 2.3e-05 0.14 41 95 .. 11 64 .. 1 71 [. 0.74 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 2.3e-05 PAS_9 41 tepeaeekleealeegkseeeelelllyrkngepfpvevtispvkdd.sgevvgvi 95 + + ++ ++ l+ + +l +l+r + e p+ + ++p+++d + +++ v+ FUN_001345-T1 11 DRKYHHLEKKRKLRKRR--TDQLRARLQRLDEEDRPTGCLLCPMRNDiEINYKNVR 64 33444444555555555..9**************************9888887765 PP >> SieB Super-infection exclusion protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 1.0 6.4e-05 0.41 55 83 .. 15 43 .. 8 45 .. 0.86 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 6.4e-05 SieB 55 lkevkerlkkkreqkeveeklknLdeeEk 83 + k+r+ +kr++++++ +l++Ldee + FUN_001345-T1 15 HHLEKKRKLRKRRTDQLRARLQRLDEEDR 43 566789999*****************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (93 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1506 (0.0589548); expected 510.9 (0.02) Passed bias filter: 857 (0.0335486); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 917.05 // Query: FUN_001346-T1 [L=131] Description: FUN_001346 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.088 13.4 0.1 0.26 11.9 0.0 1.8 2 GPR_Gpa2_C G protein-coupled glucose receptor regulating Gpa Domain annotation for each model (and alignments): >> GPR_Gpa2_C G protein-coupled glucose receptor regulating Gpa2 C-term # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 0.16 4e+03 61 71 .. 51 60 .. 25 65 .. 0.63 2 ? 11.9 0.0 1e-05 0.26 5 38 .. 78 111 .. 73 130 .. 0.76 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.16 GPR_Gpa2_C 61 lVDtlvfllre 71 lV t vfl+r+ FUN_001346-T1 51 LV-TCVFLFRQ 60 33.45666665 PP == domain 2 score: 11.9 bits; conditional E-value: 1e-05 GPR_Gpa2_C 5 kqiqrqlrsifiYPlaYillwlfPfiadalqyny 38 +q+ rq+ ++f+ P+a ++l + ++++ + + FUN_001346-T1 78 AQVLRQMGYVFVTPCAHCALCKQTKEVQVMGVVH 111 6899***************988777777777664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1560 (0.0610687); expected 510.9 (0.02) Passed bias filter: 875 (0.0342533); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1324.65 // Query: FUN_001347-T1 [L=470] Description: FUN_001347 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-39 135.2 0.8 7.8e-39 133.6 0.2 2.0 2 MPN_2A_DUB_like BRCA1-A complex subunit Abraxas 1 MPN domain 0.0017 19.2 1.1 0.0042 17.9 1.1 1.7 1 DUF641 Plant protein of unknown function (DUF641) ------ inclusion threshold ------ 0.054 13.8 0.1 0.11 12.8 0.1 1.5 1 Sec3_CC Exocyst complex component Sec3, coiled-coil 4 8.4 10.0 8.4 7.3 9.9 1.6 1 Fez1 Fez1 Domain annotation for each model (and alignments): >> MPN_2A_DUB_like BRCA1-A complex subunit Abraxas 1 MPN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 133.6 0.2 1.2e-42 7.8e-39 2 172 .] 56 227 .. 55 227 .. 0.92 2 ? -1.0 0.0 0.27 1.7e+03 1 18 [. 236 253 .. 236 261 .. 0.87 Alignments for each domain: == domain 1 score: 133.6 bits; conditional E-value: 1.2e-42 MPN_2A_DUB_like 2 lsgpalslllyenvrsesdqeGFLlGeivekvtktisdsdsqvekveteikvesvvslpllellydsagkineeklkellk...dkskevvgWy 92 lsg ++s+l+ye +s++d eG LlG+i ++++ti+ds+s++ + e+ +++ v+l++++ +y +g+i e + e l+ +ks++v+gW+ FUN_001347-T1 56 LSGCVFSSLVYELENSRGDVEGLLLGQISRRIVNTITDSQSENLRHERVATIQGFVPLDKSRRFYTGTGEIVDEIVCEELSndsEKSEKVIGWF 149 89*********************************************************************999887766512257789***** PP MPN_2A_DUB_like 93 rfrrnssnlkltlrdkllhkqlasllskvngkeelFllcllttstssnksThafehvflrsnkre.iyeavplrieNLgdk 172 +frrn+s+ ++++r++ +h +l+++l+ + +++ F+ +++t++ s + sTh+f++ f s +re ++e++++ i NLgd+ FUN_001347-T1 150 KFRRNTSS-TVSMRERFVHHNLIKKLNFT--PPKEFIFAVFTSCMSRDLSTHKFDYSFCCSSEREgVFEPLQVWILNLGDT 227 *****976.***************99886..8999***********************988766527************95 PP == domain 2 score: -1.0 bits; conditional E-value: 0.27 MPN_2A_DUB_like 1 slsgpalslllyenvrse 18 sls +a s+l+ye + s FUN_001347-T1 236 SLSAQATSSLFYEVIDSY 253 68999********99885 PP >> DUF641 Plant protein of unknown function (DUF641) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 1.1 6.6e-07 0.0042 72 123 .. 274 325 .. 249 330 .. 0.81 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 6.6e-07 DUF641 72 eseleaeiqeqrsllktyeivvkkleselkakdseieeLrekLeeaerknkk 123 ++ +++qe+ +++k e++v l +e++ ++ e+e+ r++L++ ++k ++ FUN_001347-T1 274 YITMMKKLQELVEVVKISETTVSSLTEEVEMRRREVERCRHQLRSQNEKPNE 325 45678899***********************************998876544 PP >> Sec3_CC Exocyst complex component Sec3, coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 1.8e-05 0.11 84 125 .. 276 317 .. 258 320 .. 0.84 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.8e-05 Sec3_CC 84 lLlkeLeellstvsipesdleeLke.aelssangleeleeale 125 +++k+L+el++ v+i+e ++++L+e e+++++ +e++ +l+ FUN_001347-T1 276 TMMKKLQELVEVVKISETTVSSLTEeVEMRRRE-VERCRHQLR 317 579**********************88999988.999999886 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 9.9 0.0013 8.4 32 177 .. 273 421 .. 261 426 .. 0.58 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0013 Fez1 32 eivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkknea.ellre.....kvgkleeevselreelaelsaeekelalesdeak 121 ++++ +l+el + ++ +e+++++l e++e +++e+e+c+++L+ ++++ e+++e k ++++ ++ +++l +ls + +++e d+ FUN_001347-T1 273 MYITMMKKLQELVEVVKISETTVSSLTEEVEMRRREVERCRHQLRSQNEKPnEVVEErpahpKFASCDS-NQDTEKDLIDLSDHGAGINIEDDKID 367 56888899************************************9886654144444111113333333.34445556666666666666666655 PP Fez1 122 aqrqeaeealeslkreverlkaeLkeerqrkeeqaksFeeERrtWqeeKekVirYq 177 +q++ +++++e + + +e + e + ++ k+ ++ Rr q+ +kV Yq FUN_001347-T1 368 QQQHFSTNNMEGRNDQGVWNDKEKSFESK--NNIPKAENSNRRRKQKTPSKVASYQ 421 55554433333332222222222222222..2222333344444555555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (470 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1745 (0.0683108); expected 510.9 (0.02) Passed bias filter: 701 (0.0274418); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4577.17 // Query: FUN_001348-T1 [L=348] Description: FUN_001348 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-05 25.7 21.4 1.3e-05 25.7 21.4 2.6 2 Granulin Granulin 0.0097 16.9 0.0 0.016 16.2 0.0 1.4 1 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family ------ inclusion threshold ------ 0.17 12.6 0.1 0.31 11.7 0.1 1.4 1 Methylase_S Type I restriction modification DNA specificit Domain annotation for each model (and alignments): >> Granulin Granulin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 3.1 0.099 8.4e+02 17 34 .. 274 295 .. 261 298 .. 0.59 2 ! 25.7 21.4 1.6e-09 1.3e-05 1 37 [. 294 332 .. 294 341 .. 0.86 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.099 Granulin 17 eAvCCeDgk....hCCpegytC 34 + v+C+D++ Cp++ tC FUN_001348-T1 274 DSVACRDKSgqvvTVCPSNSTC 295 5566666532223456666665 PP == domain 2 score: 25.7 bits; conditional E-value: 1.6e-09 Granulin 1 tCckl..ssgswgCCplpeAvCCeDgkhCCpegytCdlk 37 tCc + ss+ gCC l++A +C+DgkhCC +gy Cd + FUN_001348-T1 294 TCCASlfSSSGQGCCLLSQAASCSDGKHCCRAGYGCDPS 332 899885556789**********************99864 PP >> Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 1.9e-06 0.016 2 177 .. 50 227 .. 49 228 .. 0.67 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.9e-06 Lipase_GDSL_2 2 lGDSiTaGygdtggdrswpgwlarllaerl.....gadvvnnlgisGa.tt.allrllerldallrlkp...dlvvillGtNDlgrgvpparaaan 87 +GDS G ++ w+a+ll++ + ++d + +Ga + +++ l + +p d++++++G D+ +++ ++ + FUN_001348-T1 50 IGDSVSIG---------YTPWIAKLLGDGYqvqhaPWDHKD----GGAlDSkYGRQCLSLFLMTVMMEPttyDVIIFNFGLHDVNYNGEWPEEYTS 132 67777776.........456777777777744334444444....444322323444444445566666777***********9998888888777 PP Lipase_GDSL_2 88 ..nlealvrrlraa..apgarvlglgplpvgpppppdarrlnarlaalneairevaae.egvpfvdladaladddgrlpdlladdg.....lHPna 173 ++++ + ++++ + ga+v v p p++ + n + ++n++ + + ++ dl++++ ++ g+ p+ H ++ FUN_001348-T1 133 paDYAKNIGEIKSIliSTGAKVG-----YVLTTPVPYNVSINNLVLQYNDIATNLMNQqPAIAIADLYTWVVEACGDPPYNNCNIAakqpsPHYSP 223 899********999777777665.....333333333334677899999999999999899999***77777776666665333336667889999 PP Lipase_GDSL_2 174 aGyr 177 +Gy+ FUN_001348-T1 224 QGYQ 227 9987 PP >> Methylase_S Type I restriction modification DNA specificity domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 3.6e-05 0.31 54 93 .. 138 177 .. 120 187 .. 0.82 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3.6e-05 Methylase_S 54 kyilpknsilissratiGkvfyrdkkyytnqsiivlepkn 93 k+i + +silis++a++G+v +++y+++ + vl+ ++ FUN_001348-T1 138 KNIGEIKSILISTGAKVGYVLTTPVPYNVSINNLVLQYND 177 5555689*******************99999988888753 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (348 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 734 (0.0287336); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.35s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 3431.68 // Query: FUN_001349-T1 [L=2806] Description: FUN_001349 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-34 118.9 4.5 8.2e-26 91.1 0.0 6.0 5 TPR_CFAP46_N CFAP46, N-terminal TPR repeats ------ inclusion threshold ------ 0.025 15.2 2.2 68 4.5 0.1 5.6 5 TPR_8 Tetratricopeptide repeat 0.046 14.3 13.8 13 6.7 0.1 7.6 7 TPR_2 Tetratricopeptide repeat 0.2 11.7 5.0 0.097 12.7 0.4 2.6 3 RPA Replication initiator protein A 0.25 11.8 11.6 36 4.8 0.0 6.7 8 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 0.5 11.4 2.5 1.4 10.0 0.7 2.7 3 HD_assoc Phosphohydrolase-associated domain 2.5 8.6 7.5 7.8 7.0 0.1 4.9 5 TPR_1 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_CFAP46_N CFAP46, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.1 0.0 2.3e-29 8.2e-26 6 156 .. 3 148 .. 1 149 [. 0.92 2 ! 13.6 0.1 1.6e-05 0.058 57 157 .] 318 417 .. 304 417 .. 0.87 3 ? 3.4 0.1 0.021 78 129 156 .. 774 801 .. 751 802 .. 0.85 4 ! 6.6 0.0 0.0023 8.4 128 152 .. 1104 1128 .. 1031 1133 .. 0.80 5 ? -1.1 0.1 0.52 1.9e+03 60 102 .. 1716 1764 .. 1714 1845 .. 0.74 Alignments for each domain: == domain 1 score: 91.1 bits; conditional E-value: 2.3e-29 TPR_CFAP46_N 6 navkqqLaaareersvaaLerafellkelesg..rskeervsteLyvlCaEaAieleqwdvAeecLkkftekraetkalevRalycralvslheve 99 +++++++ aa++ ++ aL +a+e l++ ++ +k vs++L+vlCaEaA++ +q d+ e+ +k+f+ k+ ++ ++++Ra +c+a++ + + FUN_001349-T1 3 SNIRKLVHAASQDNDLSALTEAYEKLRKERQSsvDNKIDGVSADLFVLCAEAALKHGQFDIMEDSIKMFFLKTPPSNQFLCRAYLCQAQL---NAP 95 579************************9995545788899**************************************************...899 PP TPR_CFAP46_N 100 kslkgkekveetlecatkivaglkialeewpkeaelvlngiehlWlvirpllkaglr 156 s k+ e++++ +++ ++++++a+ ++ ++++lv+n+++ +W+ rp+lk+ +r FUN_001349-T1 96 ASSKNPEQLDK---AVEYLLKAINFAK-KNLRYYFLVYNASVLYWQFCRPFLKPNYR 148 99999998885...67899*******6.99**********************98765 PP == domain 2 score: 13.6 bits; conditional E-value: 1.6e-05 TPR_CFAP46_N 57 ieleqwdvAeecLkkft.ekraetkalevRalycralvslheve..kslkgkekveetlecatkivaglkialeewpkeaelvlngiehlWlvirp 149 +e ++ ++A +cL++++ + ++ +le+ + c+ +v + + k +k+ ve+ ++++ k + l +a+ + +++ +g +++W+ + p FUN_001349-T1 318 LENNKHELATSCLENLKgGVKSSDILLEIEFMRCELMV--QSLGekKENYSKAVVEKRIKAIRKLEQCLMTAV--RMGNPNVIQTGCVTMWNLSLP 409 567899**********9556666677899999999999..44444589999*********************8..667899*************** PP TPR_CFAP46_N 150 llkaglrh 157 ll+a lrh FUN_001349-T1 410 LLQANLRH 417 **998876 PP == domain 3 score: 3.4 bits; conditional E-value: 0.021 TPR_CFAP46_N 129 wpkeaelvlngiehlWlvirpllkaglr 156 + ke lv n++++lW+ ll++g++ FUN_001349-T1 774 ELKEPWLVCNAAVYLWNYTTHLLSQGRY 801 5678889*****************9986 PP == domain 4 score: 6.6 bits; conditional E-value: 0.0023 TPR_CFAP46_N 128 ewpkeaelvlngiehlWlvirpllk 152 ++ ++++lv+++++h+W++i+p++ FUN_001349-T1 1104 QKAENYDLVIAAARHYWNAIKPFIV 1128 577899****************975 PP == domain 5 score: -1.1 bits; conditional E-value: 0.52 TPR_CFAP46_N 60 eqwdvAeecLkkftekra.....etkalevRalycralvslheve.ksl 102 +w +++ c +++ +++a +++ l +R+l+ +a +s ++ + k++ FUN_001349-T1 1716 HKWVISDVCYRELWTEQAeilirQGQFLPARQLLTEANLSARAFDdKRC 1764 5788888888888877776666666667788888888887666654444 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.1 0.019 68 16 33 .. 103 120 .. 100 121 .. 0.87 2 ? 1.2 0.0 0.22 8e+02 3 25 .. 309 331 .. 307 333 .. 0.89 3 ? 2.7 0.1 0.071 2.6e+02 4 31 .. 445 472 .. 443 474 .. 0.85 4 ? -2.5 0.0 3.2 1.2e+04 2 27 .. 1727 1752 .. 1727 1753 .. 0.84 5 ? -0.3 0.0 0.65 2.4e+03 16 30 .. 2166 2180 .. 2161 2180 .. 0.84 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.019 TPR_8 16 dyeeAkeyyekaleldpd 33 ++++A+ey+ ka+ +++ FUN_001349-T1 103 QLDKAVEYLLKAINFAKK 120 79***********98776 PP == domain 2 score: 1.2 bits; conditional E-value: 0.22 TPR_8 3 ayynlGliylklgdyeeAkeyye 25 ++ lG+++l+ +++e A ++e FUN_001349-T1 309 LLIELGRLCLENNKHELATSCLE 331 5778**************99998 PP == domain 3 score: 2.7 bits; conditional E-value: 0.071 TPR_8 4 yynlGliylklgdyeeAkeyyekaleld 31 + l+++ + ++e A+ ++kaleld FUN_001349-T1 445 HTELAKCEEAEDQLEYAVTHLRKALELD 472 5678888889999999***********9 PP == domain 4 score: -2.5 bits; conditional E-value: 3.2 TPR_8 2 eayynlGliylklgdyeeAkeyyeka 27 e++ + i++++g++ A++ + +a FUN_001349-T1 1727 ELWTEQAEILIRQGQFLPARQLLTEA 1752 5799999********99888877766 PP == domain 5 score: -0.3 bits; conditional E-value: 0.65 TPR_8 16 dyeeAkeyyekalel 30 ++ +A+e++ +++++ FUN_001349-T1 2166 YLSQAVECLTQCVQI 2180 6789********986 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.3 0.18 6.5e+02 16 33 .. 103 120 .. 102 121 .. 0.85 2 ? 0.3 0.0 0.41 1.5e+03 4 25 .. 310 331 .. 308 333 .. 0.89 3 ? 6.7 0.1 0.0035 13 5 31 .. 446 472 .. 443 474 .. 0.91 4 ? 4.2 0.0 0.023 83 9 32 .. 1265 1288 .. 1265 1290 .. 0.91 5 ? 3.4 0.0 0.04 1.5e+02 2 27 .. 1727 1752 .. 1726 1753 .. 0.93 6 ? -3.2 0.1 5.3 1.9e+04 1 11 [. 2073 2083 .. 2073 2085 .. 0.84 7 ? -2.6 0.1 3.5 1.3e+04 22 32 .. 2148 2158 .. 2147 2160 .. 0.82 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.18 TPR_2 16 dyeeAleayekAleldPn 33 ++++A+e++ kA+ + + FUN_001349-T1 103 QLDKAVEYLLKAINFAKK 120 78**********987766 PP == domain 2 score: 0.3 bits; conditional E-value: 0.41 TPR_2 4 lynlGlayyklgdyeeAleaye 25 l +lG+++++++++e A ++e FUN_001349-T1 310 LIELGRLCLENNKHELATSCLE 331 789**************99987 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0035 TPR_2 5 ynlGlayyklgdyeeAleayekAleld 31 +l+++ ++ ++e A+ +++kAleld FUN_001349-T1 446 TELAKCEEAEDQLEYAVTHLRKALELD 472 67999*********************9 PP == domain 4 score: 4.2 bits; conditional E-value: 0.023 TPR_2 9 layyklgdyeeAleayekAleldP 32 +ay+ +g++e+ l+a+++A++ P FUN_001349-T1 1265 QAYADKGEWEQGLRAMDQAVKDMP 1288 69*****************99777 PP == domain 5 score: 3.4 bits; conditional E-value: 0.04 TPR_2 2 ealynlGlayyklgdyeeAleayekA 27 e++ +++++++++g++ A++++ +A FUN_001349-T1 1727 ELWTEQAEILIRQGQFLPARQLLTEA 1752 68999***************999988 PP == domain 6 score: -3.2 bits; conditional E-value: 5.3 TPR_2 1 aealynlGlay 11 a+ ly+lG+++ FUN_001349-T1 2073 AKTLYALGRCL 2083 6789****998 PP == domain 7 score: -2.6 bits; conditional E-value: 3.5 TPR_2 22 eayekAleldP 32 ++ ++Alel+ FUN_001349-T1 2148 QYANRALELNT 2158 7999*****95 PP >> RPA Replication initiator protein A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.4 2.7e-05 0.097 49 104 .. 436 491 .. 424 529 .. 0.73 2 ? -0.9 0.1 0.39 1.4e+03 116 191 .. 2018 2099 .. 2000 2116 .. 0.73 3 ? -2.2 0.1 0.98 3.6e+03 76 114 .. 2368 2406 .. 2350 2431 .. 0.80 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.7e-05 RPA 49 iliflisqlveaknkgrpvsrlvrltayellkatnrdtsgreykrLkealeRLqgt 104 +l+ l q+ + +k ++ + +++ + +l ka + d sg +y rL+ al RLq FUN_001349-T1 436 LLVLLRCQMHTELAKCEEAEDQLEYAVTHLRKALELDDSGMYYDRLQTALTRLQLR 491 4555667888888888888999******************************9842 PP == domain 2 score: -0.9 bits; conditional E-value: 0.39 RPA 116 ersegfslidewkiv....tekegrlsavevtlsdwlyravlakevltidrdYfrlrk..pleRrlYrLaRkhcgrqeelwr 191 ++ + ++id++ v te+e++ v tl++ ++ ++ ++ +t + +Y++ + l+R l La + e++w+ FUN_001349-T1 2018 QKGSIQKMIDDFVSVeptpTEREQKWIDVTRTLAEDIMMQLSMAHAMTGNVAYLKAKTlyALGRCLAVLAAHTSPDSESQWK 2099 22233478998888877665668888999999*********************97664338999998888665555555575 PP == domain 3 score: -2.2 bits; conditional E-value: 0.98 RPA 76 yellkatnrdtsgreykrLkealeRLqgttitttiragg 114 +++r+ r+ ++ +++l++L+ t+++t++++ FUN_001349-T1 2368 NTASELMRRNYVKRQQEQKRKMLAKLEDTSLHTENQQPS 2406 556678899999999999999**********99977654 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 1.3 4.7e+03 56 79 .. 173 196 .. 157 204 .. 0.88 2 ? 4.3 0.0 0.013 49 39 106 .. 289 356 .. 264 370 .. 0.82 3 ? 3.1 0.3 0.032 1.2e+02 13 60 .. 448 495 .. 440 535 .. 0.74 4 ? -2.4 0.0 1.6 5.7e+03 49 77 .. 588 616 .. 570 620 .. 0.74 5 ? -3.4 0.0 3.3 1.2e+04 22 40 .. 898 916 .. 894 921 .. 0.74 6 ? -1.1 0.0 0.62 2.3e+03 54 92 .. 1254 1292 .. 1216 1305 .. 0.74 7 ? 4.8 0.0 0.0098 36 55 120 .. 1724 1792 .. 1692 1800 .. 0.83 8 ? -1.7 0.1 0.99 3.6e+03 51 76 .. 1937 1962 .. 1890 1993 .. 0.63 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.3 ARM_TT21 56 kvsvylelidvlsklkkveeAkkl 79 ++++ + li+++ ++++ e+A+++ FUN_001349-T1 173 RAQLMIALIECHVDAGRKEDATQI 196 678999***************997 PP == domain 2 score: 4.3 bits; conditional E-value: 0.013 ARM_TT21 39 kkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaieefkgtpeevrillanaelala 106 ++++++++++ +s++d++ +++el +++ +++k e A++ l++ + k + +i ++++el+++ FUN_001349-T1 289 GTSTSKTSSPRLVSSNDRIPLLIELGRLCLENNKHELATSCLENLKGGVKSSDILLEIEFMRCELMVQ 356 334455667788899******************************99999999999999999999886 PP == domain 3 score: 3.1 bits; conditional E-value: 0.032 ARM_TT21 13 kakvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvy 60 ak++++e++le A+++L++Al+l + ++ ++ + + ++++y FUN_001349-T1 448 LAKCEEAEDQLEYAVTHLRKALELDDSGMYYDRLQTALTRLQLRATLY 495 5999********************876655566555555555555555 PP == domain 4 score: -2.4 bits; conditional E-value: 1.6 ARM_TT21 49 kessesdkvsvylelidvlsklkkveeAk 77 + +++++v+++ l+++ +k++ ++ A+ FUN_001349-T1 588 GDENDQERVRIWADLAKTARKQQVWDAAR 616 456789*************9997776665 PP == domain 5 score: -3.4 bits; conditional E-value: 3.3 ARM_TT21 22 kleeAlktLktAlklpgkk 40 +l++Al++L+ Al++++ + FUN_001349-T1 898 DLKQALEVLEYALNTTNGE 916 6889999999999987654 PP == domain 6 score: -1.1 bits; conditional E-value: 0.62 ARM_TT21 54 sdkvsvylelidvlsklkkveeAkkllqeaieefkgtpe 92 ++++y l +++++ +++e+ +++++a+++ t++ FUN_001349-T1 1254 MLRAAMYGVLFQAYADKGEWEQGLRAMDQAVKDMPRTHH 1292 367899999*************99999999998877764 PP == domain 7 score: 4.8 bits; conditional E-value: 0.0098 ARM_TT21 55 dkvsvylelidvlsklkkveeAkkllqeai...eefkgtpeevrillanaelalargdvdkAlelLkki 120 ++++e +++l +++++ A++ll ea+ + f ++ ++ill a +ala+ + +A +lL + FUN_001349-T1 1724 CYRELWTEQAEILIRQGQFLPARQLLTEANlsaRAFDDKRCLSNILLQFAVMALAESNWGQATSLLLEA 1792 4447999**********************877789999************************9999665 PP == domain 8 score: -1.7 bits; conditional E-value: 0.99 ARM_TT21 51 ssesdkvsvylelidvlsklkkveeA 76 s +++ +le d+l+++ ++++A FUN_001349-T1 1937 DSPEERQDYFLEAFDTLKEAARLSDA 1962 24467777788888888877777776 PP >> HD_assoc Phosphohydrolase-associated domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 2.2 8.1e+03 74 90 .. 751 767 .. 749 768 .. 0.88 2 ? -4.0 0.0 7 2.6e+04 24 48 .. 2007 2031 .. 1999 2039 .. 0.73 3 ? 10.0 0.7 0.00037 1.4 9 67 .. 2360 2418 .. 2355 2430 .. 0.85 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 2.2 HD_assoc 74 aDyiAgmTDryalrlhr 90 +D+iA+++ + + + hr FUN_001349-T1 751 CDWIASLSNEVIHSFHR 767 9*******999988886 PP == domain 2 score: -4.0 bits; conditional E-value: 7 HD_assoc 24 rhpevkreeekareiireLfealla 48 ++++ kre+e ++ i+++ + +++ FUN_001349-T1 2007 EESREKRERETQKGSIQKMIDDFVS 2031 5667778888888888888777765 PP == domain 3 score: 10.0 bits; conditional E-value: 0.00037 HD_assoc 9 aelaeLKkflfenvyrhpevkreeekareiireLfealladpelLppefrerleeaedd 67 +e +K+ ++ +++r++ vkr++e+ r+++++L ++ l+++++ p+++ + ++e+e + FUN_001349-T1 2360 EEFCLFKSNTASELMRRNYVKRQQEQKRKMLAKLEDTSLHTENQQPSNVDSSFAEKEAQ 2418 66778899999******************************99*9*9999999777763 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.3 0.11 4.1e+02 16 29 .. 103 116 .. 102 121 .. 0.84 2 ? -1.3 0.0 0.88 3.2e+03 4 25 .. 310 331 .. 308 332 .. 0.86 3 ? 7.0 0.1 0.0021 7.8 4 31 .. 445 472 .. 443 474 .. 0.90 4 ? -1.8 0.1 1.3 4.7e+03 21 31 .. 2147 2157 .. 2147 2159 .. 0.89 5 ? -3.6 0.0 4.6 1.7e+04 19 30 .. 2169 2180 .. 2168 2180 .. 0.88 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.11 TPR_1 16 kydeAleyyekALe 29 ++d+A+ey kA+ FUN_001349-T1 103 QLDKAVEYLLKAIN 116 79**********96 PP == domain 2 score: -1.3 bits; conditional E-value: 0.88 TPR_1 4 lynlGnayfklgkydeAleyye 25 l lG ++++++k++ A + e FUN_001349-T1 310 LIELGRLCLENNKHELATSCLE 331 5679*************88876 PP == domain 3 score: 7.0 bits; conditional E-value: 0.0021 TPR_1 4 lynlGnayfklgkydeAleyyekALeln 31 + l+ + + +++ A+ + +kALel+ FUN_001349-T1 445 HTELAKCEEAEDQLEYAVTHLRKALELD 472 56799999999****************9 PP == domain 4 score: -1.8 bits; conditional E-value: 1.3 TPR_1 21 leyyekALeln 31 l+y ++ALeln FUN_001349-T1 2147 LQYANRALELN 2157 68999*****8 PP == domain 5 score: -3.6 bits; conditional E-value: 4.6 TPR_1 19 eAleyyekALel 30 +A+e+ +++++ FUN_001349-T1 2169 QAVECLTQCVQI 2180 8*******9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2806 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1715 (0.0671364); expected 510.9 (0.02) Passed bias filter: 673 (0.0263457); expected 510.9 (0.02) Passed Vit filter: 94 (0.00367978); expected 25.5 (0.001) Passed Fwd filter: 29 (0.00113525); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.83u 0.44s 00:00:01.27 Elapsed: 00:00:00.46 # Mc/sec: 24838.22 // Query: FUN_001350-T1 [L=1290] Description: FUN_001350 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-22 78.1 0.1 1.9e-21 76.7 0.1 1.8 1 ARID ARID/BRIGHT DNA binding domain ------ inclusion threshold ------ 0.15 12.3 0.6 25 5.2 0.3 2.6 2 DUF7599 Domain of unknown function (DUF7599) 3.9 8.5 6.8 0.43 11.6 0.6 2.8 3 LIAS_N N-terminal domain of lipoyl synthase of Radical_SAM Domain annotation for each model (and alignments): >> ARID ARID/BRIGHT DNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.7 0.1 2.3e-25 1.9e-21 2 90 .] 609 694 .. 608 694 .. 0.95 Alignments for each domain: == domain 1 score: 76.7 bits; conditional E-value: 2.3e-25 ARID 2 keeFlkqLkkfhekrgtplkkiPkiggkpldLykLykaVqkrGGyekvtkkkkWrevaeklglppeqskatsaatqlkkiYekyLlpye 90 ++ F+++L++f++k ++pl k+P +g k+++L+++yk+ q++GGy++vt+k++Wr+v+++lg +++ tsaat +++Ye++Llpye FUN_001350-T1 609 EKYFMQTLQDFMKKTNQPLGKLPALGFKKVNLWTMYKTAQRFGGYDAVTSKRLWRRVYDSLGGSTT---ITSAATYTRRHYERLLLPYE 694 678****************88****************************************98744...5799***************8 PP >> DUF7599 Domain of unknown function (DUF7599) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.3 0.0029 25 14 82 .. 558 625 .. 556 627 .. 0.80 2 ? 4.4 0.0 0.0048 41 32 60 .. 652 680 .. 643 696 .. 0.82 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.0029 DUF7599 14 LeeakgkvlvvsdlkkalgyrgkrghraWrrilkrLkkaglveefeakvngkvvrclrLlkkfspkefe 82 Le+ + ++vs+ kk+ +++++ aW++ +krL g v+ ++ ++ +++ l++f +k+ + FUN_001350-T1 558 LENEERLPVFVSNKKKENKVDKTEEAIAWKKKKKRLRMPGSVKDEIYD-DEDEKYFMQTLQDFMKKTNQ 625 56666667889999****************************987655.44566777777777777665 PP == domain 2 score: 4.4 bits; conditional E-value: 0.0048 DUF7599 32 gyrgkrghraWrrilkrLkkaglveefea 60 gy+ + +r Wrr+ + L + + + FUN_001350-T1 652 GYDAVTSKRLWRRVYDSLGGSTTITSAAT 680 899999************99888876655 PP >> LIAS_N N-terminal domain of lipoyl synthase of Radical_SAM family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.6 5.1e-05 0.43 6 69 .. 541 603 .. 535 624 .. 0.80 2 ? -2.6 0.1 1.3 1.1e+04 11 63 .. 718 770 .. 712 773 .. 0.78 3 ? -3.6 0.1 2.7 2.3e+04 35 53 .. 939 957 .. 929 989 .. 0.50 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 5.1e-05 LIAS_N 6 lsssaatsssltdekkelleeGPdldDfvsgdledkskweeykgnlkrekge.rlrLPswlktki 69 + ss++++ssl + k le+ l fvs++++++ k ++ ++ + +k++ rlr+P +k +i FUN_001350-T1 541 I-SSVTANSSLHVKSKPSLENEERLPVFVSNKKKEN-KVDKTEEAIAWKKKKkRLRMPGSVKDEI 603 4.447788888999999***************9999.5666677766555444******999988 PP == domain 2 score: -2.6 bits; conditional E-value: 1.3 LIAS_N 11 atsssltdekkelleeGPdldDfvsgdledkskweeykgnlkrekgerlrLPs 63 +++ +++kk++l+ +++ s ++d sk ++k++ +++ + ++P+ FUN_001350-T1 718 PKETPSKSDKKQALAVANSMSKHKSCTNPDGSKAVDLKKDSMIKESTHSKVPQ 770 55566678888899988999999999999999999999888888888888886 PP == domain 3 score: -3.6 bits; conditional E-value: 2.7 LIAS_N 35 sgdledkskweeykgnlkr 53 s+d++ +s+ + y l++ FUN_001350-T1 939 SDDSPPQSQSKSYAVCLVQ 957 4444444444444333322 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1290 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1346 (0.0526913); expected 510.9 (0.02) Passed bias filter: 560 (0.0219221); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.43u 0.42s 00:00:00.85 Elapsed: 00:00:00.41 # Mc/sec: 12529.93 // Query: FUN_001350-T2 [L=1182] Description: FUN_001350 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-22 78.3 0.1 1.7e-21 76.9 0.1 1.8 1 ARID ARID/BRIGHT DNA binding domain ------ inclusion threshold ------ 0.12 12.6 0.6 22 5.3 0.3 2.6 2 DUF7599 Domain of unknown function (DUF7599) 4.1 8.4 7.3 0.41 11.6 0.7 2.9 3 LIAS_N N-terminal domain of lipoyl synthase of Radical_SAM Domain annotation for each model (and alignments): >> ARID ARID/BRIGHT DNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.9 0.1 2e-25 1.7e-21 2 90 .] 501 586 .. 500 586 .. 0.95 Alignments for each domain: == domain 1 score: 76.9 bits; conditional E-value: 2e-25 ARID 2 keeFlkqLkkfhekrgtplkkiPkiggkpldLykLykaVqkrGGyekvtkkkkWrevaeklglppeqskatsaatqlkkiYekyLlpye 90 ++ F+++L++f++k ++pl k+P +g k+++L+++yk+ q++GGy++vt+k++Wr+v+++lg +++ tsaat +++Ye++Llpye FUN_001350-T2 501 EKYFMQTLQDFMKKTNQPLGKLPALGFKKVNLWTMYKTAQRFGGYDAVTSKRLWRRVYDSLGGSTT---ITSAATYTRRHYERLLLPYE 586 678****************88****************************************98744...5799***************8 PP >> DUF7599 Domain of unknown function (DUF7599) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.3 0.0026 22 14 82 .. 450 517 .. 448 519 .. 0.80 2 ? 4.6 0.0 0.0044 37 32 60 .. 544 572 .. 535 588 .. 0.82 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0026 DUF7599 14 LeeakgkvlvvsdlkkalgyrgkrghraWrrilkrLkkaglveefeakvngkvvrclrLlkkfspkefe 82 Le+ + ++vs+ kk+ +++++ aW++ +krL g v+ ++ ++ +++ l++f +k+ + FUN_001350-T2 450 LENEERLPVFVSNKKKENKVDKTEEAIAWKKKKKRLRMPGSVKDEIYD-DEDEKYFMQTLQDFMKKTNQ 517 56666667889999****************************987655.44566777777777777665 PP == domain 2 score: 4.6 bits; conditional E-value: 0.0044 DUF7599 32 gyrgkrghraWrrilkrLkkaglveefea 60 gy+ + +r Wrr+ + L + + + FUN_001350-T2 544 GYDAVTSKRLWRRVYDSLGGSTTITSAAT 572 899999************99888876655 PP >> LIAS_N N-terminal domain of lipoyl synthase of Radical_SAM family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.7 4.8e-05 0.41 6 69 .. 433 495 .. 427 517 .. 0.80 2 ? -2.4 0.1 1.2 1e+04 11 63 .. 610 662 .. 604 665 .. 0.78 3 ? -3.4 0.1 2.4 2e+04 15 34 .. 838 857 .. 821 882 .. 0.50 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.8e-05 LIAS_N 6 lsssaatsssltdekkelleeGPdldDfvsgdledkskweeykgnlkrekge.rlrLPswlktki 69 + ss++++ssl + k le+ l fvs++++++ k ++ ++ + +k++ rlr+P +k +i FUN_001350-T2 433 I-SSVTANSSLHVKSKPSLENEERLPVFVSNKKKEN-KVDKTEEAIAWKKKKkRLRMPGSVKDEI 495 4.447788888999999***************9999.5666677766555444******999988 PP == domain 2 score: -2.4 bits; conditional E-value: 1.2 LIAS_N 11 atsssltdekkelleeGPdldDfvsgdledkskweeykgnlkrekgerlrLPs 63 +++ +++kk++l+ +++ s ++d sk ++k++ +++ + ++P+ FUN_001350-T2 610 PKETPSKSDKKQALAVANSMSKHKSCTNPDGSKAVDLKKDSMIKESTHSKVPQ 662 55566678888899999999999999999999999999888888888888886 PP == domain 3 score: -3.4 bits; conditional E-value: 2.4 LIAS_N 15 sltdekkelleeGPdldDfv 34 s+++ +l +GP+ + + FUN_001350-T2 838 SQSKSYAVCLVQGPQQNAEM 857 22333334444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1228 (0.048072); expected 510.9 (0.02) Passed bias filter: 473 (0.0185163); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.47u 0.34s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 11425.78 // Query: FUN_001351-T1 [L=338] Description: FUN_001351 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-08 35.2 10.4 4.1e-08 33.4 10.4 2.0 1 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 1.7e-08 34.6 8.2 4.5e-08 33.3 8.2 1.8 1 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 5.4e-08 33.5 8.2 5.4e-08 33.5 8.2 2.2 2 zf-RING_2 Ring finger domain 3.9e-07 30.4 8.9 3.9e-07 30.4 8.9 1.9 1 zf-RING_5 zinc-RING finger domain 9.3e-07 29.2 6.8 9.3e-07 29.2 6.8 2.0 1 zf-RING_UBOX RING-type zinc-finger 1.1e-05 26.1 4.9 3.6e-05 24.4 4.9 1.9 1 zf-rbx1 RING-H2 zinc finger domain 4.8e-05 23.6 10.6 0.00019 21.6 10.6 2.0 1 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 0.00033 21.0 8.1 0.00097 19.5 2.6 2.5 2 Prok-RING_4 Prokaryotic RING finger family 4 0.0015 18.8 7.4 0.0015 18.8 7.4 2.0 2 zf-RING_4 RING/Ubox like zinc-binding domain 0.0063 17.1 7.0 0.032 14.8 3.1 2.6 2 zf-C3HC4_4 zinc finger of C3HC4-type, RING 0.0081 16.7 4.1 0.02 15.4 4.1 1.6 1 zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H ------ inclusion threshold ------ 0.035 14.3 4.3 0.05 13.8 2.5 2.3 2 zf-RING_11 RING-like zinc finger 0.038 14.5 12.3 10 6.7 8.0 3.6 2 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING 0.1 13.2 9.4 0.56 10.9 9.1 2.2 2 zf-RING_10 zinc RING finger of MSL2 0.12 12.9 9.4 0.53 10.8 9.4 2.1 1 Zn_ribbon_6 Double zinc ribbon 0.75 10.2 6.2 2.9 8.3 6.2 2.1 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit 0.86 10.3 9.0 15 6.3 9.0 2.6 1 Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING 0.92 10.2 11.7 0.17 12.6 5.2 2.5 2 DUF4196 Domain of unknown function (DUF4196) 1 9.9 2.8 17 6.0 0.3 2.4 2 DUF2187 Uncharacterized protein conserved in bacteri 1.2 9.7 8.1 5.1 7.8 8.1 2.1 1 FYVE FYVE zinc finger 5 7.6 6.9 7.1 7.1 2.6 2.5 2 IBR_1 IBR domain 7.6 7.1 8.6 30 5.2 8.6 2.0 2 zf-RING_DCST1_C E3 ubiquitin-protein ligase DCST1-like, C-te Domain annotation for each model (and alignments): >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.4 10.4 3.5e-11 4.1e-08 2 40 .] 280 324 .. 279 324 .. 0.85 Alignments for each domain: == domain 1 score: 33.4 bits; conditional E-value: 3.5e-11 zf-C3HC4_2 2 CpiCld......mlkdplvvtpCgHvfCqkCilraLeesneCPlC 40 CpiC+d + k l++t CgHvfC kCi+ a + + +CP+C FUN_001351-T1 280 CPICMDddkaikRRKSQLMSTTCGHVFCDKCIRSAVQLQRRCPTC 324 *****9554333345679999************************ PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 8.2 3.9e-11 4.5e-08 1 40 [] 280 324 .. 280 324 .. 0.96 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 3.9e-11 zf-C3HC4 1 CpiCleelkepv......tllpCgHsfCssCiksllesnnvkCplC 40 CpiC++ k + ++++CgH fC +Ci+s ++ ++ Cp+C FUN_001351-T1 280 CPICMDDDKAIKrrksqlMSTTCGHVFCDKCIRSAVQ-LQRRCPTC 324 ********9999999**9*******************.7788**** PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 2.9 3.4e+03 5 21 .. 205 222 .. 202 225 .. 0.77 2 ! 33.5 8.2 4.6e-11 5.4e-08 2 44 .] 279 325 .. 278 325 .. 0.76 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2.9 zf-RING_2 5 iCleeleeeekvivlp.C 21 +C +++ ++ +++lp C FUN_001351-T1 205 VCVNQIYHRDPAHRLPsC 222 788888888888888767 PP == domain 2 score: 33.5 bits; conditional E-value: 4.6e-11 zf-RING_2 2 eCpiCl..eeleeeek..vivlpCgHvfhkeCldkwlrtsstCPlCr 44 +CpiC+ ++ +++k ++ + CgHvf+ +C++ ++ +++CP+Cr FUN_001351-T1 279 TCPICMddDKAIKRRKsqLMSTTCGHVFCDKCIRSAVQLQRRCPTCR 325 7****944233333332344667***********************9 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 8.9 3.3e-10 3.9e-07 2 43 .] 280 326 .. 279 326 .. 0.90 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 3.3e-10 zf-RING_5 2 CnkCfkel....sktrkfyltsCgHifCeeClkkll.eerqCpiCkk 43 C++C+++ + +++++ t+CgH+fC++C+ +r+Cp+C+k FUN_001351-T1 280 CPICMDDDkaikRRKSQLMSTTCGHVFCDKCIRSAVqLQRRCPTCRK 326 99**9998887777888***************9999899******97 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 6.8 8e-10 9.3e-07 1 38 [. 280 324 .. 280 325 .. 0.77 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 8e-10 zf-RING_UBOX 1 CpICleeft.....dP.lv.lpCGHtfCreClwelskkekgkikC 38 CpIC+++ + + l+ ++CGH+fC +C+++ + +++ +C FUN_001351-T1 280 CPICMDDDKaikrrKSqLMsTTCGHVFCDKCIRSAVQLQRRCPTC 324 ******9999998722566579**********6566666666555 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 4.9 3.1e-08 3.6e-05 10 55 .] 276 325 .. 272 325 .. 0.85 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 3.1e-08 zf-rbx1 10 leeacieckapgdee....cpvvwGeCgHaFHlhCiskWlktrntCPlcr 55 ++ +c+ c ++++ +++ +CgH+F +Ci++ ++ +++CP+cr FUN_001351-T1 276 YDITCPICMDDDKAIkrrkSQLMSTTCGHVFCDKCIRSAVQLQRRCPTCR 325 5667888887777767777889999************************8 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 10.6 1.7e-07 0.00019 4 46 .. 279 328 .. 276 330 .. 0.83 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.7e-07 zf-C3HC4_3 4 eCviCle.......rernvvllpCgHlclCeeCaeklr.kkkkCpiCrqki 46 +C iC++ r+++ + + CgH+ +C +C ++ +++Cp Cr+k FUN_001351-T1 279 TCPICMDddkaikrRKSQLMSTTCGHV-FCDKCIRSAVqLQRRCPTCRKKL 328 799**995555544467788889****.*********999********986 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.2 0.051 59 28 38 .. 274 285 .. 271 291 .. 0.72 2 ! 19.5 2.6 8.4e-07 0.00097 7 41 .. 293 329 .. 288 333 .. 0.78 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.051 Prok-RING_4 28 sdfs.aCPiCrr 38 +++ CPiC FUN_001351-T1 274 KNYDiTCPICMD 285 666678****84 PP == domain 2 score: 19.5 bits; conditional E-value: 8.4e-07 Prok-RING_4 7 eetkivlspCgHlvCkeCfds.sdfs.aCPiCrrrvd 41 ++ + + CgH+ C++C s +++ CP Cr++++ FUN_001351-T1 293 RKSQLMSTTCGHVFCDKCIRSaVQLQrRCPTCRKKLS 329 555666678*********9872466679******987 PP >> zf-RING_4 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2.6 3e+03 28 44 .. 206 223 .. 203 226 .. 0.51 2 ! 18.8 7.4 1.3e-06 0.0015 1 46 [. 280 327 .. 280 329 .. 0.90 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.6 zf-RING_4 28 Cyedile.eeegrCPgCr 44 C ++i + + r P Cr FUN_001351-T1 206 CVNQIYHrDPAHRLPSCR 223 444444424455556665 PP == domain 2 score: 18.8 bits; conditional E-value: 1.3e-06 zf-RING_4 1 cplCdekl...detdkdllPCeCgyqiClfCyedileeeegrCPgCree 46 cp+C+++ + ++l+ Cg+ +C C +++ + rCP Cr++ FUN_001351-T1 280 CPICMDDDkaiKRRKSQLMSTTCGHVFCDKCIRSAVQ-LQRRCPTCRKK 327 999*98755569999*******************996.8********96 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.12 1.4e+02 31 42 .] 272 283 .. 263 285 .. 0.61 2 ! 14.8 3.1 2.8e-05 0.032 12 42 .] 298 324 .. 295 324 .. 0.86 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.12 zf-C3HC4_4 31 epdgesllCplC 42 e+++ + +Cp C FUN_001351-T1 272 EQKNYDITCPIC 283 555555666666 PP == domain 2 score: 14.8 bits; conditional E-value: 2.8e-05 zf-C3HC4_4 12 vsieCGhsfClsCisslqkepdgesllCplC 42 +s CGh+fC +Ci s + + Cp C FUN_001351-T1 298 MSTTCGHVFCDKCIRSAVQLQRR----CPTC 324 7889**********999887766....8887 PP >> zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 4.1 1.7e-05 0.02 10 64 .. 275 331 .. 273 332 .. 0.76 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.7e-05 zf-ANAPC11 10 sfdGtcPeckvPGd.....dcplvlGkckhsfhlhcilkWletetskglcPmcrqtfklk 64 ++d tcP c + l+ c h+f + ci + + + +cP cr+++ lk FUN_001351-T1 275 NYDITCPICMDDDKaikrrKSQLMSTTCGHVFCDKCIRSAV---QLQRRCPTCRKKLSLK 331 699999999644321111156788999**********9866...56889******99887 PP >> zf-RING_11 RING-like zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 3.9 4.6e+03 4 20 .. 205 222 .. 205 223 .. 0.67 2 ? 13.8 2.5 4.3e-05 0.05 2 29 .] 280 311 .. 279 311 .. 0.81 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 3.9 zf-RING_11 4 ICleefkpgq.alfvlpC 20 +C +++ + + a +++ C FUN_001351-T1 205 VCVNQIYHRDpAHRLPSC 222 688888877734466668 PP == domain 2 score: 13.8 bits; conditional E-value: 4.3e-05 zf-RING_11 2 CsIClee...fk.pgqalfvlpCsHvFHykCi 29 C IC+++ +k + +l+ + C+HvF kCi FUN_001351-T1 280 CPICMDDdkaIKrRKSQLMSTTCGHVFCDKCI 311 *****97444664455999999*********9 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.018 21 33 51 .. 265 283 .. 254 289 .. 0.72 2 ? 6.7 8.0 0.0088 10 12 54 .. 297 327 .. 291 330 .. 0.74 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.018 RING_XB3-XBAT31 33 kkkteaataskespaCPfC 51 +++++++++++ ++CP+C FUN_001351-T1 265 SSSSSPKEQKNYDITCPIC 283 445556667778899**** PP == domain 2 score: 6.7 bits; conditional E-value: 0.0088 RING_XB3-XBAT31 12 ieveeCgHqlCaqCalalcskkkkteaataskespaCPfCRss 54 + ++CgH +C +C+ + ++ ++ CP CR++ FUN_001351-T1 297 LMSTTCGHVFCDKCIRSAVQLQR------------RCPTCRKK 327 56689**********88777653............37777765 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 1.2 1.4e+03 15 37 .. 269 291 .. 261 297 .. 0.73 2 ? 10.9 9.1 0.00048 0.56 18 45 .. 299 326 .. 278 333 .. 0.87 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 1.2 zf-RING_10 15 tpkeseCqHyvCrlCvgkkkklk 37 +pke++ C C+ ++k +k FUN_001351-T1 269 SPKEQKNYDITCPICMDDDKAIK 291 67777777778888888888776 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00048 zf-RING_10 18 eseCqHyvCrlCvgkkkklkpsCskCkd 45 +++C+H C +C++ +l+ +C++C++ FUN_001351-T1 299 STTCGHVFCDKCIRSAVQLQRRCPTCRK 326 679***********************84 PP >> Zn_ribbon_6 Double zinc ribbon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 9.4 0.00046 0.53 2 41 .. 279 330 .. 241 335 .. 0.83 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00046 Zn_ribbon_6 2 kCpkCqqele...kre........eeyhCeaCqe.elklealCpdCgeelev 41 +Cp C + +r+ +++C+ C + ++l+ +Cp+C+++l++ FUN_001351-T1 279 TCPICMDDDKaikRRKsqlmsttcGHVFCDKCIRsAVQLQRRCPTCRKKLSL 330 6777754333111333677777779999999977699************986 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 6.2 0.0025 2.9 7 56 .. 273 324 .. 271 325 .. 0.75 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0025 zf-Nse 7 eekislkcPltl......qpfkePvtskkCnHvfekeaIlellkrkkkvkCPvvgC 56 +++ +++cP+ + + k + s++C+Hvf + I + + + +++CP C FUN_001351-T1 273 QKNYDITCPICMdddkaiKRRKSQLMSTTCGHVFCDKCIRSAV--QLQRRCPT--C 324 6677888999762221113456678899***************..89999**8..7 PP >> Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 9.0 0.013 15 11 35 .] 296 324 .. 280 324 .. 0.65 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.013 Sina_RING 11 pIlqCenGHliCssCrpkl...t.kCptC 35 + GH++C +C + + +CptC FUN_001351-T1 296 QLMSTTCGHVFCDKCIRSAvqlQrRCPTC 324 5556678********8875344348**** PP >> DUF4196 Domain of unknown function (DUF4196) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 5.2 0.00015 0.17 4 71 .. 49 114 .. 46 120 .. 0.86 2 ? 0.7 0.4 0.69 8.1e+02 6 57 .. 241 294 .. 236 308 .. 0.56 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00015 DUF4196 4 nsstseeeknktkersidlsdkekrlsqeeddlkkhtgqiieeDleeekikrGkrkrlssvleDsdds 71 sst+ee + t++++ + + +e++l +++ +++ +t +i+e+ +e++ k++r +Ds+ds FUN_001351-T1 49 LSSTQEESECLTRKNKRNRPHVENKLRENHTESTGETLPLINEESPDENLSSDKKRRRI--ADDSEDS 114 589**************************************999999999887655543..3777777 PP == domain 2 score: 0.7 bits; conditional E-value: 0.69 DUF4196 6 stseeeknktkersidlsdkekrlsqeeddlkkhtgqiiee.Dl.eeekikrGk 57 st+++e +++++++ + +++ + s ++++ +i+ + ++ ikr k FUN_001351-T1 241 STCNDEVQEVSNNDANSTQDSSLNSSSSSPKEQKNYDITCPiCMdDDKAIKRRK 294 677777777776666655555555555555555555555320232344455544 PP >> DUF2187 Uncharacterized protein conserved in bacteria (DUF2187) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.3 0.028 32 28 43 .. 168 183 .. 162 185 .. 0.78 2 ? 6.0 0.3 0.015 17 28 48 .. 182 201 .. 178 208 .. 0.81 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.028 DUF2187 28 nSVivdltimdnfkdl 43 SV+vdlt n++d FUN_001351-T1 168 GSVVVDLTNDANLHDS 183 6*******77777775 PP == domain 2 score: 6.0 bits; conditional E-value: 0.015 DUF2187 28 nSVivdltimdnfkdlelefe 48 +S +vdlt dn +d +++ + FUN_001351-T1 182 DSNVVDLT-RDNSSDSSFDTN 201 789*****.********9954 PP >> FYVE FYVE zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 8.1 0.0044 5.1 10 60 .. 279 323 .. 270 330 .. 0.65 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0044 FYVE 10 eCseCkkeFtllrrrh...HCrkCGkvfCskCsskkislleelkeekpvrvCde 60 +C +C + + ++rr CG+vfC+kC+++ ++l+ r C + FUN_001351-T1 279 TCPICMDDDKAIKRRKsqlMSTTCGHVFCDKCIRSAVQLQ---------RRCPT 323 57777776655544441115689**********9999554.........44444 PP >> IBR_1 IBR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 2.6 0.0061 7.1 4 37 .. 278 312 .. 275 313 .. 0.74 2 ? 1.6 0.1 0.31 3.6e+02 5 16 .. 320 331 .. 317 335 .. 0.79 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0061 IBR_1 4 ieCpkCkfryelar.gcmhftCkqCkheFCsgCkr 37 i+Cp C+ + + ++ + C h FC +C r FUN_001351-T1 278 ITCPICMDDDKAIKrRKSQLMSTTCGHVFCDKCIR 312 6899998655444446666777889********86 PP == domain 2 score: 1.6 bits; conditional E-value: 0.31 IBR_1 5 eCpkCkfryela 16 +Cp C+ + +l+ FUN_001351-T1 320 RCPTCRKKLSLK 331 699999888876 PP >> zf-RING_DCST1_C E3 ubiquitin-protein ligase DCST1-like, C-terminal RING domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.2 2 2.3e+03 38 44 .. 279 285 .. 275 286 .. 0.78 2 ? 5.2 8.6 0.026 30 19 44 .. 298 326 .. 278 327 .. 0.67 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 2 zf-RING_DCST1_C 38 tClvCap 44 tC +C+ FUN_001351-T1 279 TCPICMD 285 7999985 PP == domain 2 score: 5.2 bits; conditional E-value: 0.026 zf-RING_DCST1_C 19 stpgCkgvYCreCfr...dlgntClvCap 44 +++C v+C++C r +l++ C C + FUN_001351-T1 298 MSTTCGHVFCDKCIRsavQLQRRCPTCRK 326 3689*********9944458999***986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (338 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1643 (0.0643179); expected 510.9 (0.02) Passed bias filter: 781 (0.0305735); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 22 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3257.88 // Query: FUN_001352-T1 [L=198] Description: FUN_001352 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-52 178.8 19.4 1.5e-52 178.6 19.4 1.0 1 SPATA24 Spermatogenesis-associated protein 24 ------ inclusion threshold ------ 0.035 13.4 0.6 0.035 13.4 0.6 1.5 2 Phage_F Capsid protein (F protein) 0.044 14.4 2.2 0.095 13.3 2.2 1.5 1 DCX2_DCDC1 DCDC1, second doublecortin-like domain 0.11 13.3 3.2 0.11 13.2 1.5 2.0 2 DWNN DWNN domain 0.28 12.1 1.4 2.6 8.9 0.2 2.3 2 SPG48 AP-5 complex subunit, vesicle trafficking 2.9 8.8 8.6 7 7.5 0.3 3.0 2 DUF5965 Family of unknown function (DUF5965) 3.1 8.4 6.2 2.5 8.7 0.9 2.3 2 SLATT_fungal SMODS and SLOG-associating 2TM effector domain Domain annotation for each model (and alignments): >> SPATA24 Spermatogenesis-associated protein 24 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 178.6 19.4 4e-56 1.5e-52 4 175 .. 10 180 .. 7 186 .. 0.96 Alignments for each domain: == domain 1 score: 178.6 bits; conditional E-value: 4e-56 SPATA24 4 ssvslvqstlkdlfevqekvleklrrvaelqeekfvskeeyeavkkkleeEkveHaktkllLakEeEkLkfAlgeieiLskqlekekkafekalss 99 s+++v+++l+d++ q++v+ ++++ + + ++ vs++ey++ +++leeEk++H +tk+ La E+EkL+fAlgei+iL+kq+++ek fe++ ++ FUN_001352-T1 10 PSYAIVNKQLQDVIRFQHTVIARMKAKMSRTDD-RVSRDEYDKLVRELEEEKLNHVRTKAKLAGESEKLQFALGEIDILNKQIQREKATFENVYGQ 104 5899************************98876.59************************************************************ PP SPATA24 100 vkskalqEskkkDqLiekCseieseiirqeDilnakeneikeLkqrlskqkeifrqqlsdlrikkqqEvYmakvld 175 vk ka++E ++k q ++kC+++e+ + +q+Dil +k+ +ikeLkqrl +qk++++qqlsdl+i++qqE Y+ + + FUN_001352-T1 105 VKTKAMEENQEKKQFLTKCQAMEELCSKQDDILTTKDAKIKELKQRLIRQKQVHQQQLSDLDIHRQQEQYINYSTQ 180 **********************************************************************987665 PP >> Phage_F Capsid protein (F protein) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 0.51 1.9e+03 358 394 .. 22 60 .. 21 69 .. 0.82 2 ? 13.4 0.6 9.5e-06 0.035 364 434 .. 121 190 .. 115 195 .. 0.89 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 0.51 Phage_F 358 vvradltyqqglerlwsreqlry..DlydPalanlgeqe 394 v+r+++t +++++sr +r D yd ++ +l e + FUN_001352-T1 22 VIRFQHTVIARMKAKMSRTDDRVsrDEYDKLVRELEEEK 60 579999999999999999988887888888888887765 PP == domain 2 score: 13.4 bits; conditional E-value: 9.5e-06 Phage_F 364 tyqqglerlwsreqlryDlydPalanlgeqevsnkeiyvqgsaqdsekfgyqEryaeyRykpskvagkfrs 434 t+ q +e+l s++ + d ++++l ++ + +k++ q++ +d + + qE+y++y ++ s v+ k r+ FUN_001352-T1 121 TKCQAMEELCSKQDDILTTKDAKIKELKQRLIRQKQVH-QQQLSDLDIHRQQEQYINYSTQKSPVNPKSRT 190 67789999999977777888******************.99999**********************99886 PP >> DCX2_DCDC1 DCDC1, second doublecortin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 2.2 2.6e-05 0.095 13 82 .. 91 160 .. 83 166 .. 0.86 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.6e-05 DCX2_DCDC1 13 kkvrilvfkNgegtegveivadkdkvekfLdacTkkleLtsparllydweGeeiedlsevplldkclqks 82 ++ +f+N g+ +++ + ++++ ++fL++c + eL s+ + ++ +i++l++ + +k ++++ FUN_001352-T1 91 IQREKATFENVYGQVKTKAMEENQEKKQFLTKCQAMEELCSKQDDILTTKDAKIKELKQRLIRQKQVHQQ 160 4555578***************************************************988877766554 PP >> DWNN DWNN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.3 8.4e+03 14 21 .. 23 30 .. 13 50 .. 0.62 2 ? 13.2 1.5 3.1e-05 0.11 21 73 .. 142 195 .. 132 196 .. 0.83 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.3 DWNN 14 itfdgtsi 21 i f++t i FUN_001352-T1 23 IRFQHTVI 30 33333333 PP == domain 2 score: 13.2 bits; conditional E-value: 3.1e-05 DWNN 21 isvsdLKreIieqkklgkgtdfdLkiynaqtne.eykddsalIprntsVivrRv 73 ++++LK+ i+qk++ +++ dL+i +q++ +y+ + ++ +++ +Rv FUN_001352-T1 142 AKIKELKQRLIRQKQVHQQQLSDLDIHRQQEQYiNYSTQKSPVNPKSRTHLKRV 195 5789**********************9888776788888888877777777766 PP >> SPG48 AP-5 complex subunit, vesicle trafficking # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.13 4.8e+02 12 42 .. 18 48 .. 12 56 .. 0.87 2 ? 8.9 0.2 0.00071 2.6 11 49 .. 124 162 .. 115 179 .. 0.88 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.13 SPG48 12 lLdelcrqdeslvyralptlkklfqrlssdl 42 L+ ++r ++ +++r+ +++ + +r+s+d FUN_001352-T1 18 QLQDVIRFQHTVIARMKAKMSRTDDRVSRDE 48 6899999999************999999875 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00071 SPG48 11 klLdelcrqdeslvyralptlkklfqrlssdlsqarvlL 49 + ++elc+++ ++++ +++k+l qrl ++ + ++ L FUN_001352-T1 124 QAMEELCSKQDDILTTKDAKIKELKQRLIRQKQVHQQQL 162 689*************************99999888665 PP >> DUF5965 Family of unknown function (DUF5965) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 2.7 0.032 1.2e+02 6 31 .. 39 67 .. 27 117 .. 0.78 2 ? 7.5 0.3 0.0019 7 4 39 .. 144 179 .. 142 186 .. 0.94 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.032 DUF5965 6 rlaekvarqe.ekvake..teklesyreq 31 r ++v+r e +k+ +e ekl++ r + FUN_001352-T1 39 RTDDRVSRDEyDKLVREleEEKLNHVRTK 67 45567777664566665224677777765 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0019 DUF5965 4 ikrlaekvarqeekvaketeklesyreqlqsamyst 39 ik l +++ rq + ++ l+ +r+q q yst FUN_001352-T1 144 IKELKQRLIRQKQVHQQQLSDLDIHRQQEQYINYST 179 899**********999******************99 PP >> SLATT_fungal SMODS and SLOG-associating 2TM effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.9 0.0007 2.5 61 100 .. 29 66 .. 28 107 .. 0.72 2 ? 2.4 0.4 0.061 2.2e+02 74 114 .. 109 150 .. 103 157 .. 0.65 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0007 SLATT_fungal 61 vLAllkgsglPersrkrrkelekvireieatefeldagev 100 v+A++k++ r r+e++k++re+e+ +l++ + FUN_001352-T1 29 VIARMKAKMSRTDDRVSRDEYDKLVRELEE--EKLNHVRT 66 79****************************..55555422 PP == domain 2 score: 2.4 bits; conditional E-value: 0.061 SLATT_fungal 74 srkrrkelekvireieatefeldag.evgldveeeveelrrr 114 + + +e +++ ++++a+e + + + ++ +++++++el +r FUN_001352-T1 109 AMEENQEKKQFLTKCQAMEELCSKQdDILTTKDAKIKELKQR 150 455666778888888887777666633333445777777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (198 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3588 (0.140458); expected 510.9 (0.02) Passed bias filter: 686 (0.0268546); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.35u 0.35s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1949.35 // Query: FUN_001353-T1 [L=99] Description: FUN_001353 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 345 (0.0135056); expected 510.9 (0.02) Passed bias filter: 331 (0.0129575); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.39s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 1035.43 // Query: FUN_001354-T1 [L=1166] Description: FUN_001354 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-131 418.8 47.9 7.6e-09 35.9 0.2 20.1 20 Ank Ankyrin repeat 1.2e-120 394.9 23.1 5.8e-19 68.9 0.7 9.4 9 Ank_2 Ankyrin repeats (3 copies) 3.9e-114 370.4 48.7 2.7e-12 47.1 0.1 17.2 17 Ank_4 Ankyrin repeats (many copies) 2.1e-108 353.4 31.6 2.4e-11 44.2 0.5 14.7 14 Ank_5 Ankyrin repeats (many copies) 3.6e-97 305.8 22.8 6.6e-06 26.5 0.1 19.3 19 Ank_3 Ankyrin repeat 4.1e-36 124.4 5.4 0.00036 20.8 0.0 9.5 10 Ank_KRIT1 KRIT1 ankyrin-repeats domain 7.7e-24 84.8 1.7 1e-20 74.6 0.1 2.3 2 PARP Poly(ADP-ribose) polymerase catalytic domain 1.4e-14 54.4 0.5 3.1e-14 53.4 0.5 1.5 1 SAM_2 SAM domain (Sterile alpha motif) 3e-13 50.2 1.1 2.2 8.6 0.1 8.8 10 ANK_LRRK2 LRRK2 ANK repeat 1.6e-12 48.1 0.4 3.4e-12 47.0 0.4 1.5 1 SAM_1 SAM domain (Sterile alpha motif) ------ inclusion threshold ------ 0.011 15.5 7.6 0.048 13.4 0.2 3.9 5 Amidohydro_1 Amidohydrolase family 0.13 12.8 0.3 24 5.5 0.1 3.6 3 DUF7855 DUF7855 N-terminal dimerisation domain 0.2 12.6 0.0 1.2e+02 3.7 0.0 4.2 5 NTF2_4 NTF2-like domain Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.13 2.5e+02 7 32 .. 25 50 .. 24 51 .. 0.89 2 ! 28.6 0.0 8.2e-10 1.6e-06 4 33 .] 57 86 .. 54 86 .. 0.93 3 ! 33.4 0.1 2.3e-11 4.5e-08 2 33 .] 88 119 .. 87 119 .. 0.94 4 ! 31.2 0.1 1.2e-10 2.4e-07 2 32 .. 121 151 .. 120 152 .. 0.92 5 ? -2.9 0.0 8.4 1.7e+04 1 9 [. 153 161 .. 153 166 .. 0.86 6 ! 35.3 0.1 5.7e-12 1.1e-08 3 33 .] 209 239 .. 207 239 .. 0.95 7 ! 29.1 0.2 5.6e-10 1.1e-06 2 32 .. 241 271 .. 240 272 .. 0.93 8 ! 24.7 0.1 1.4e-08 2.8e-05 3 32 .. 275 304 .. 273 305 .. 0.91 9 ! 11.7 0.0 0.0002 0.39 6 33 .] 365 395 .. 362 395 .. 0.89 10 ! 29.4 0.1 4.3e-10 8.4e-07 3 32 .. 398 427 .. 396 428 .. 0.94 11 ! 24.2 0.1 2.1e-08 4e-05 2 31 .. 430 459 .. 429 461 .. 0.92 12 ? 4.9 0.0 0.028 56 8 32 .. 495 518 .. 493 519 .. 0.81 13 ! 31.8 0.0 7.5e-11 1.5e-07 3 33 .] 524 554 .. 522 554 .. 0.93 14 ! 26.1 0.4 5e-09 9.9e-06 2 32 .. 556 586 .. 555 587 .. 0.92 15 ! 26.7 0.0 3.3e-09 6.5e-06 3 32 .. 590 619 .. 588 620 .. 0.91 16 ! 7.3 0.0 0.0048 9.5 1 25 [. 621 642 .. 621 652 .. 0.80 17 ! 35.9 0.2 3.9e-12 7.6e-09 3 33 .] 677 707 .. 675 707 .. 0.94 18 ! 25.8 0.2 6.4e-09 1.3e-05 2 33 .] 709 740 .. 708 740 .. 0.93 19 ! 26.0 0.0 5.5e-09 1.1e-05 3 32 .. 743 772 .. 741 773 .. 0.94 20 ? 1.1 0.0 0.46 9.1e+02 2 21 .. 775 790 .. 774 797 .. 0.74 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.13 Ank 7 HlAaraghlevvklLLkhGAdvnard 32 A+r+g++ v+ +++ + +vn+rd FUN_001354-T1 25 FEACRNGDVTKVRRIVNTNSNVNLRD 50 579*************779*****98 PP == domain 2 score: 28.6 bits; conditional E-value: 8.2e-10 Ank 4 TPLHlAaraghlevvklLLkhGAdvnardk 33 +PLH Aa g+ +vv++LL+ GAdv+a+d+ FUN_001354-T1 57 SPLHFAAGFGRKDVVEYLLQFGADVHAKDD 86 8******99**********88*******96 PP == domain 3 score: 33.4 bits; conditional E-value: 2.3e-11 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G PLH A++ gh evv++LL+hGAd+n rd+ FUN_001354-T1 88 GLIPLHNACSFGHAEVVRILLRHGADPNSRDN 119 778******************99*******97 PP == domain 4 score: 31.2 bits; conditional E-value: 1.2e-10 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH Aa +g ++v+ LL+hGAd+n+r+ FUN_001354-T1 121 NYTPLHEAAVKGKVDVCVVLLQHGADPNIRN 151 58****99978**********99******99 PP == domain 5 score: -2.9 bits; conditional E-value: 8.4 Ank 1 dGnTPLHlA 9 dG T+L +A FUN_001354-T1 153 DGKTALDVA 161 79****987 PP == domain 6 score: 35.3 bits; conditional E-value: 5.7e-12 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnardk 33 TPLHlAa ++++ vv+lLL+hGAdv+a+dk FUN_001354-T1 209 STPLHLAAGYNRVRVVQLLLQHGADVHAKDK 239 5*******99**********99*******97 PP == domain 7 score: 29.1 bits; conditional E-value: 5.6e-10 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G PLH A+++gh++v +lL+khGA+vna d FUN_001354-T1 241 GLVPLHNACSYGHYDVTELLIKHGASVNAMD 271 778******************99*****988 PP == domain 8 score: 24.7 bits; conditional E-value: 1.4e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH Aa++ ++ev+ lLL hGAd+ + + FUN_001354-T1 275 FTPLHEAASKARVEVCSLLLAHGADPTLLN 304 7*******99**********88****8765 PP == domain 9 score: 11.7 bits; conditional E-value: 0.0002 Ank 6 LHlAa...raghlevvklLLkhGAdvnardk 33 LHlA+ + ++ + ++ LLk+GAd n+++k FUN_001354-T1 365 LHLAVssvCPKRKSAIEVLLKKGADTNLQNK 395 9****999777789******88******997 PP == domain 10 score: 29.4 bits; conditional E-value: 4.3e-10 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 TPLH+A+++ hl+ v+lL+k+GA vna+d FUN_001354-T1 398 LTPLHIASEKSHLDAVELLIKNGAKVNAVD 427 6*******99**********98******98 PP == domain 11 score: 24.2 bits; conditional E-value: 2.1e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnar 31 G T+LH Aa ag+++ +++LL+hGAd+ +r FUN_001354-T1 430 GETALHRAAAAGQTSACRILLSHGADISLR 459 99****99989**********99***9876 PP == domain 12 score: 4.9 bits; conditional E-value: 0.028 Ank 8 lAaraghlevvklLLkhGAdvnard 32 Aar g++evvk L+ vnard FUN_001354-T1 495 EAARSGDMEVVKKLC-TPQTVNARD 518 69*9**********9.555688877 PP == domain 13 score: 31.8 bits; conditional E-value: 7.5e-11 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnardk 33 TPLH Aa ++++ vv++LL++GAdv+a+dk FUN_001354-T1 524 STPLHFAAGYNRVGVVEYLLQNGADVHAKDK 554 6*******999999******99*******97 PP == domain 14 score: 26.1 bits; conditional E-value: 5e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G PLH A+++gh+ev++lL+khGA vn+ d FUN_001354-T1 556 GLVPLHNACSYGHYEVAELLVKHGAVVNVAD 586 778******************99**999987 PP == domain 15 score: 26.7 bits; conditional E-value: 3.3e-09 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH A+ +g e+++lLLkhGAd+ ++ FUN_001354-T1 590 FTPLHEASAKGKFEICRLLLKHGADPQKKT 619 7*******99**********99***98776 PP == domain 16 score: 7.3 bits; conditional E-value: 0.0048 Ank 1 dGnTPLHlAaraghlevvklLLkhG 25 dG+TPL l ++ g+++v+ lL G FUN_001354-T1 621 DGQTPLDL-VKDGDTDVADLLR--G 642 7*******.999*******986..4 PP == domain 17 score: 35.9 bits; conditional E-value: 3.9e-12 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnardk 33 TPLHlAa ++h ev++ LL++GAdvna+dk FUN_001354-T1 677 STPLHLAAGYNHFEVAEHLLENGADVNAQDK 707 6*******99**********98*******97 PP == domain 18 score: 25.8 bits; conditional E-value: 6.4e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G PLH A+++gh++++ lL+kh+ dvna+d+ FUN_001354-T1 709 GLIPLHNASSYGHVDIASLLIKHNTDVNATDR 740 778******************99******995 PP == domain 19 score: 26.0 bits; conditional E-value: 5.5e-09 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH Aa++g+++++ lLL hGAd+ ++ FUN_001354-T1 743 FTPLHEAAQKGRTQLCALLLAHGADPTMKN 772 7*******************88****9998 PP == domain 20 score: 1.1 bits; conditional E-value: 0.46 Ank 2 GnTPLHlAaraghlevvklL 21 G+T+L lA a + vk L FUN_001354-T1 775 GQTALDLAT-AED---VKCL 790 9******99.563...4444 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.7 0.0 1.3e-20 2.5e-17 1 90 [] 24 118 .. 24 118 .. 0.94 2 ! 29.9 0.0 4.6e-10 9e-07 19 67 .. 111 161 .. 111 170 .. 0.91 3 ! 60.1 0.4 1.7e-19 3.3e-16 1 90 [] 178 271 .. 178 271 .. 0.88 4 ! 48.8 0.1 5.6e-16 1.1e-12 19 88 .. 231 302 .. 231 304 .. 0.94 5 ! 68.9 0.7 3e-22 5.8e-19 1 88 [. 365 458 .. 365 460 .. 0.91 6 ! 59.6 0.1 2.4e-19 4.7e-16 1 90 [] 493 586 .. 493 586 .. 0.88 7 ! 26.2 0.0 6.4e-09 1.3e-05 26 79 .. 586 640 .. 582 645 .. 0.82 8 ! 60.2 0.5 1.5e-19 3e-16 1 90 [] 646 739 .. 646 739 .. 0.91 9 ! 25.3 0.2 1.3e-08 2.5e-05 31 80 .. 744 791 .. 740 798 .. 0.83 Alignments for each domain: == domain 1 score: 63.7 bits; conditional E-value: 1.3e-20 Ank_2 1 LmlAakngnlelvklLl.egadanlqdk..ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 L+ A++ng+ v++++ ++++nl+d+ ++ ++Lh+Aa g++++v++Ll++gadv d+ g +Lh A++ gh e+v++Ll +gad+n++d FUN_001354-T1 24 LFEACRNGDVTKVRRIVnTNSNVNLRDTagRKSSPLHFAAGFGRKDVVEYLLQFGADVHakDDGGLIPLHNACSFGHAEVVRILLRHGADPNSRD 118 789**************989999999999999**********************9887777899****************************997 PP == domain 2 score: 29.9 bits; conditional E-value: 4.6e-10 Ank_2 19 gadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyA 67 gad+n++d+++ t+Lh Aa +g+++++ +Ll+hgad n + +g+taL +A FUN_001354-T1 111 GADPNSRDNWNYTPLHEAAVKGKVDVCVVLLQHGADPNirNTDGKTALDVA 161 6899*999*99***********************99888899******999 PP == domain 3 score: 60.1 bits; conditional E-value: 1.7e-19 Ank_2 1 LmlAakngnlelvklLl..egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 L Aa++gn e + Ll +++++ d ++ t+LhlAa ++++ +v+lLl+hgadv d+ g +Lh A+++gh+++ +lL+++ga++na d FUN_001354-T1 178 LLEAARSGNEEKLMSLLtpLNVNCHASDGRKSTPLHLAAGYNRVRVVQLLLQHGADVHakDKGGLVPLHNACSYGHYDVTELLIKHGASVNAMD 271 6789***999777777746666666666699***********************9977879******************************987 PP == domain 4 score: 48.8 bits; conditional E-value: 5.6e-16 Ank_2 19 gadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadina 88 gad++ +dk g +Lh A+++gh ++ +lL++hga+vn d + t+Lh Aa++ ++e++ lLl +gad+++ FUN_001354-T1 231 GADVHAKDKGGLVPLHNACSYGHYDVTELLIKHGASVNamDLWQFTPLHEAASKARVEVCSLLLAHGADPTL 302 5788999999************************999999999**************************985 PP == domain 5 score: 68.9 bits; conditional E-value: 3e-22 Ank_2 1 LmlAak..n.gnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadina 88 L+lA++ + ++++ Ll +gad+nlq+k+ t+Lh+A ++ hl++v+lL+++ga+vn d g+taLh Aa g+ ++++Ll++gadi + FUN_001354-T1 365 LHLAVSsvCpKRKSAIEVLLkKGADTNLQNKDSLTPLHIASEKSHLDAVELLIKNGAKVNavDALGETALHRAAAAGQTSACRILLSHGADISL 458 78888865324558*****************************************99999999****************************986 PP == domain 6 score: 59.6 bits; conditional E-value: 2.4e-19 Ank_2 1 LmlAakngnlelvklLlegadanlqdk..ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 L Aa++g+ e+vk L ++ +n +d + t+Lh+Aa ++++ +v++Ll++gadv d+ g +Lh A+++gh+e+++lL+++ga +n+ d FUN_001354-T1 493 LLEAARSGDMEVVKKLCTPQTVNARDLegRHSTPLHFAAGYNRVGVVEYLLQNGADVHakDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD 586 678*************945455544554577**********************99877879***************************999876 PP == domain 7 score: 26.2 bits; conditional E-value: 6.4e-09 Ank_2 26 dkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklL 79 d ++ t+Lh A +g+ ei++lLl+hgad + +++g+t+L + + g +++ lL FUN_001354-T1 586 DLWKFTPLHEASAKGKFEICRLLLKHGADPQkkTRDGQTPLDLV-KDGDTDVADLL 640 55789*********************9886668899*****987.46777887776 PP == domain 8 score: 60.2 bits; conditional E-value: 1.5e-19 Ank_2 1 LmlAakngnlelvklLlegadanlqdk..ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 L Aak+gnl v L + ++n++d+ ++ t+LhlAa ++h e+++ Lle+gadvn d+ g +Lh A+++gh++i+ lL++++ d+na+d FUN_001354-T1 646 LLDAAKKGNLTRVMKLSTPENINCRDTqgRNSTPLHLAAGYNHFEVAEHLLENGADVNaqDKGGLIPLHNASSYGHVDIASLLIKHNTDVNATD 739 5679***999777777658888888887788***********************9999999******************************997 PP == domain 9 score: 25.3 bits; conditional E-value: 1.3e-08 Ank_2 31 taLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLl 80 t+Lh Aa++g+++++ lLl+hgad +++g+taL +A+ e vk Ll FUN_001354-T1 744 TPLHEAAQKGRTQLCALLLAHGADPTmkNQEGQTALDLATA----EDVKCLL 791 9********************9885556799********85....4455555 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 6.3e-09 1.2e-05 1 50 [] 24 75 .. 24 75 .. 0.95 2 ! 47.1 0.1 1.4e-15 2.7e-12 1 50 [] 59 108 .. 59 108 .. 0.98 3 ! 16.8 0.1 4.7e-06 0.0093 11 38 .. 102 129 .. 100 129 .. 0.95 4 ! 27.5 0.0 2e-09 3.9e-06 1 37 [. 125 161 .. 125 161 .. 0.97 5 ! 22.9 0.0 5.5e-08 0.00011 2 50 .] 179 228 .. 178 228 .. 0.93 6 ! 43.7 0.3 1.6e-14 3.1e-11 1 50 [] 212 261 .. 212 261 .. 0.98 7 ! 41.6 0.1 7.1e-14 1.4e-10 1 50 [] 245 294 .. 245 294 .. 0.99 8 ! 29.8 0.0 3.7e-10 7.2e-07 6 50 .] 370 417 .. 365 417 .. 0.88 9 ! 41.7 0.2 6.7e-14 1.3e-10 2 50 .] 402 450 .. 402 450 .. 0.97 10 ! 19.7 0.0 5.7e-07 0.0011 2 50 .] 494 543 .. 493 543 .. 0.90 11 ! 44.7 0.1 7.8e-15 1.5e-11 1 50 [] 527 576 .. 527 576 .. 0.98 12 ! 33.2 0.1 3.1e-11 6.1e-08 2 49 .. 561 608 .. 561 608 .. 0.98 13 ! 25.7 0.0 7.4e-09 1.4e-05 1 45 [. 593 636 .. 593 641 .. 0.86 14 ! 16.6 0.0 5.3e-06 0.01 1 49 [. 646 695 .. 646 696 .. 0.87 15 ! 44.0 0.3 1.3e-14 2.6e-11 1 50 [] 680 729 .. 680 729 .. 0.98 16 ! 28.5 0.2 9.4e-10 1.8e-06 7 50 .] 719 762 .. 719 762 .. 0.96 17 ! 24.9 0.1 1.3e-08 2.5e-05 1 38 [. 746 783 .. 746 790 .. 0.95 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 6.3e-09 Ank_4 1 lhaAaksghlellklLlengadinatdgnge..taLhfAasngnlevlklLl 50 l+ A+ g++ +++++++ ++n +d g+ ++LhfAa +g+ +v+++Ll FUN_001354-T1 24 LFEACRNGDVTKVRRIVNTNSNVNLRDTAGRksSPLHFAAGFGRKDVVEYLL 75 789***********************99999667*****************8 PP == domain 2 score: 47.1 bits; conditional E-value: 1.4e-15 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh+Aa +g+ +++++Ll++gad++a d+ g +Lh+A+s+g+ ev++ Ll FUN_001354-T1 59 LHFAAGFGRKDVVEYLLQFGADVHAKDDGGLIPLHNACSFGHAEVVRILL 108 8*********************************************9997 PP == domain 3 score: 16.8 bits; conditional E-value: 4.7e-06 Ank_4 11 ellklLlengadinatdgngetaLhfAa 38 e+++ Ll +gad+n +d++ +t+Lh Aa FUN_001354-T1 102 EVVRILLRHGADPNSRDNWNYTPLHEAA 129 89***********************997 PP == domain 4 score: 27.5 bits; conditional E-value: 2e-09 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfA 37 lh Aa++g+++++ Ll++gad+n ++ +g taL+ A FUN_001354-T1 125 LHEAAVKGKVDVCVVLLQHGADPNIRNTDGKTALDVA 161 8*********************************876 PP == domain 5 score: 22.9 bits; conditional E-value: 5.5e-08 Ank_4 2 haAaksghlellklLl.engadinatdgngetaLhfAasngnlevlklLl 50 Aa sg++e l +Ll ++++a+dg t+Lh Aa ++++v++lLl FUN_001354-T1 179 LEAARSGNEEKLMSLLtPLNVNCHASDGRKSTPLHLAAGYNRVRVVQLLL 228 67999********9997789*****************************7 PP == domain 6 score: 43.7 bits; conditional E-value: 1.6e-14 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh Aa ++++++++lLl++gad++a d+ g +Lh+A+s g+++v +lL+ FUN_001354-T1 212 LHLAAGYNRVRVVQLLLQHGADVHAKDKGGLVPLHNACSYGHYDVTELLI 261 799**********************************************8 PP == domain 7 score: 41.6 bits; conditional E-value: 7.1e-14 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh A+++gh+++ +lL+++ga++na d +++t+Lh Aas+ ++ev++lLl FUN_001354-T1 245 LHNACSYGHYDVTELLIKHGASVNAMDLWQFTPLHEAASKARVEVCSLLL 294 8***********************************************97 PP == domain 8 score: 29.8 bits; conditional E-value: 3.7e-10 Ank_4 6 k...sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 + + +++ Ll++gad n ++++ t+Lh+A+ +++l++++lL+ FUN_001354-T1 370 SsvcPKRKSAIEVLLKKGADTNLQNKDSLTPLHIASEKSHLDAVELLI 417 5555668899*************************************8 PP == domain 9 score: 41.7 bits; conditional E-value: 6.7e-14 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 h A +++hl++++lL++nga +na+d getaLh+Aa+ g++++++ Ll FUN_001354-T1 402 HIASEKSHLDAVELLIKNGAKVNAVDALGETALHRAAAAGQTSACRILL 450 8899****************************************99987 PP == domain 10 score: 19.7 bits; conditional E-value: 5.7e-07 Ank_4 2 haAaksghlellklLlengadinatdgnge..taLhfAasngnlevlklLl 50 Aa sg++e++k L ++ +na+d +g+ t+LhfAa +++ v+++Ll FUN_001354-T1 494 LEAARSGDMEVVKKL-CTPQTVNARDLEGRhsTPLHFAAGYNRVGVVEYLL 543 6799*********96.88888999998888889*****************8 PP == domain 11 score: 44.7 bits; conditional E-value: 7.8e-15 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh+Aa ++++ ++++Ll+ngad++a d+ g +Lh+A+s g++ev++lL+ FUN_001354-T1 527 LHFAAGYNRVGVVEYLLQNGADVHAKDKGGLVPLHNACSYGHYEVAELLV 576 8***********************************************96 PP == domain 12 score: 33.2 bits; conditional E-value: 3.1e-11 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 h A+++gh+e+++lL+++ga +n d + +t+Lh A+++g +e+++lL FUN_001354-T1 561 HNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEASAKGKFEICRLL 608 88*******************************************998 PP == domain 13 score: 25.7 bits; conditional E-value: 7.4e-09 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlev 45 lh A ++g++e+++lLl++gad+ + ++g+t+L+ + + g+++v FUN_001354-T1 593 LHEASAKGKFEICRLLLKHGADPQKKTRDGQTPLDLV-KDGDTDV 636 8*********************************976.5555555 PP == domain 14 score: 16.6 bits; conditional E-value: 5.3e-06 Ank_4 1 lhaAaksghlellklLlengadinatdgnge..taLhfAasngnlevlklL 49 l +Aak+g+l + L + +in++d +g+ t+Lh Aa +++ev++ L FUN_001354-T1 646 LLDAAKKGNLTRVMKLS-TPENINCRDTQGRnsTPLHLAAGYNHFEVAEHL 695 56899999999999975.8889****99988779*************9866 PP == domain 15 score: 44.0 bits; conditional E-value: 1.3e-14 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 lh Aa ++h+e+++ Llengad+na+d+ g +Lh+A+s g++++++lL+ FUN_001354-T1 680 LHLAAGYNHFEVAEHLLENGADVNAQDKGGLIPLHNASSYGHVDIASLLI 729 799**********************************************8 PP == domain 16 score: 28.5 bits; conditional E-value: 9.4e-10 Ank_4 7 sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 +gh++++ lL+++ d+natd++ +t+Lh Aa++g+++ + lLl FUN_001354-T1 719 YGHVDIASLLIKHNTDVNATDRWLFTPLHEAAQKGRTQLCALLL 762 59************************************999997 PP == domain 17 score: 24.9 bits; conditional E-value: 1.3e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAa 38 lh Aa +g+++l+ lLl++gad+ + + +g+taL+ A FUN_001354-T1 746 LHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLAT 783 8**********************************996 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.7 0.0 8.9e-10 1.7e-06 3 54 .. 41 93 .. 39 93 .. 0.93 2 ! 36.0 0.2 4.5e-12 8.9e-09 19 56 .] 91 128 .. 90 128 .. 0.97 3 ! 41.5 0.1 8.3e-14 1.6e-10 1 56 [] 107 161 .. 107 161 .. 0.98 4 ! 37.7 0.1 1.3e-12 2.6e-09 7 53 .. 199 245 .. 194 245 .. 0.96 5 ! 33.4 0.1 3.1e-11 6e-08 1 44 [. 227 269 .. 227 273 .. 0.96 6 ! 21.5 0.1 1.7e-07 0.00033 1 54 [. 260 312 .. 260 314 .. 0.92 7 ! 41.1 0.1 1.1e-13 2.2e-10 1 56 [] 383 437 .. 383 437 .. 0.97 8 ! 21.1 0.1 2.2e-07 0.00044 16 56 .] 430 470 .. 424 470 .. 0.93 9 ! 33.9 0.0 2.1e-11 4.1e-08 7 53 .. 514 560 .. 509 560 .. 0.89 10 ! 32.9 0.3 4.2e-11 8.3e-08 1 46 [. 542 586 .. 542 588 .. 0.96 11 ! 31.2 0.0 1.4e-10 2.8e-07 1 55 [. 575 628 .. 575 629 .. 0.95 12 ! 44.2 0.5 1.2e-14 2.4e-11 6 54 .. 666 714 .. 663 716 .. 0.95 13 ! 15.5 0.1 1.2e-05 0.024 19 47 .. 712 740 .. 711 741 .. 0.96 14 ! 38.3 0.1 8.7e-13 1.7e-09 1 56 [] 728 782 .. 728 782 .. 0.95 Alignments for each domain: == domain 1 score: 28.7 bits; conditional E-value: 8.9e-10 Ank_5 3 eng.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 + +++l ++ g++ pLh+Aa g+ ++v++Ll +g+d+++kd+ gl pl+ FUN_001354-T1 41 NTNsNVNLRDTAGRKSSPLHFAAGFGRKDVVEYLLQFGADVHAKDDGGLIPLH 93 55668999*****************************************9996 PP == domain 2 score: 36.0 bits; conditional E-value: 4.5e-12 Ank_5 19 pLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 pLh+A++ g++e+vr+Ll +g+d+n +d++++tpl+ A FUN_001354-T1 91 PLHNACSFGHAEVVRILLRHGADPNSRDNWNYTPLHEA 128 8**********************************976 PP == domain 3 score: 41.5 bits; conditional E-value: 8.3e-14 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 Ll +g ad+n++d++ ytpLh Aa +g ++ +Ll +g+d+n+++ +g+t+ld+A FUN_001354-T1 107 LLRHG-ADPNSRDNWNYTPLHEAAVKGKVDVCVVLLQHGADPNIRNTDGKTALDVA 161 899*9.************************************************98 PP == domain 4 score: 37.7 bits; conditional E-value: 1.3e-12 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++++++dg++ tpLh+Aa y++ ++v+lLl +g+d+++kd+ gl pl FUN_001354-T1 199 VNCHASDGRKSTPLHLAAGYNRVRVVQLLLQHGADVHAKDKGGLVPL 245 89*****************************************9997 PP == domain 5 score: 33.4 bits; conditional E-value: 3.1e-11 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnl 44 Ll++g ad++++d++g pLh+A++yg++++ +lL+++g+++n+ FUN_001354-T1 227 LLQHG-ADVHAKDKGGLVPLHNACSYGHYDVTELLIKHGASVNA 269 89***.***********************************997 PP == domain 6 score: 21.5 bits; conditional E-value: 1.7e-07 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 L+++g a++n+ d + +tpLh Aa++ + e+ lLla+g+d++l + + + ++d FUN_001354-T1 260 LIKHG-ASVNAMDLWQFTPLHEAASKARVEVCSLLLAHGADPTLLNCHSKAAVD 312 899**.99999**************99999999999********9988888887 PP == domain 7 score: 41.1 bits; conditional E-value: 1.1e-13 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 Ll+ g ad+n +++++ tpLh+A+++ +l+ v+lL++ng+ +n+ d+ g+t+l+ A FUN_001354-T1 383 LLKKG-ADTNLQNKDSLTPLHIASEKSHLDAVELLIKNGAKVNAVDALGETALHRA 437 78999.***********************************************977 PP == domain 8 score: 21.1 bits; conditional E-value: 2.2e-07 Ank_5 16 gytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 g+t+Lh Aa +g r+Ll +g+d+ l+ ++g t+ ++A FUN_001354-T1 430 GETALHRAAAAGQTSACRILLSHGADISLRSFQGHTAAEVA 470 78***********************************9988 PP == domain 9 score: 33.9 bits; conditional E-value: 2.1e-11 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++ +l+g+ tpLh+Aa y++ +v++Ll ng+d+++kd+ gl pl FUN_001354-T1 514 VNARDLEGRHSTPLHFAAGYNRVGVVEYLLQNGADVHAKDKGGLVPL 560 45566777777********************************9997 PP == domain 10 score: 32.9 bits; conditional E-value: 4.2e-11 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkd 46 Ll+ng ad++++d++g pLh+A++yg++e+++lL+++g+ +n+ d FUN_001354-T1 542 LLQNG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD 586 89***.**********************************999876 PP == domain 11 score: 31.2 bits; conditional E-value: 1.4e-10 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldl 55 L+++g a +n d +++tpLh A+ +g +ei rlLl++g+d+ k+ +g+tpldl FUN_001354-T1 575 LVKHG-AVVNVADLWKFTPLHEASAKGKFEICRLLLKHGADPQKKTRDGQTPLDL 628 78999.88888999****************************************8 PP == domain 12 score: 44.2 bits; conditional E-value: 1.2e-14 Ank_5 6 padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 ++++ ++ g+ tpLh+Aa y+++e+++ Ll+ng+d+n++d+ gl pl+ FUN_001354-T1 666 NINCRDTQGRNSTPLHLAAGYNHFEVAEHLLENGADVNAQDKGGLIPLH 714 5899*******************************************97 PP == domain 13 score: 15.5 bits; conditional E-value: 1.2e-05 Ank_5 19 pLhvAakygaleivrlLlangvdlnlkde 47 pLh+A++yg+ +i+ lL++++ d+n++d FUN_001354-T1 712 PLHNASSYGHVDIASLLIKHNTDVNATDR 740 8**************************97 PP == domain 14 score: 38.3 bits; conditional E-value: 8.7e-13 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 L+++ d+n++d++ +tpLh Aa +g+ ++ lLla+g+d+++k+ eg+t+ldlA FUN_001354-T1 728 LIKHN-TDVNATDRWLFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLA 782 56665.89***********************************************9 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.088 1.7e+02 6 30 .. 24 47 .. 24 48 .. 0.84 2 ! 23.5 0.0 3.2e-08 6.3e-05 4 30 .. 57 82 .. 54 83 .. 0.94 3 ! 22.1 0.1 9.5e-08 0.00019 5 30 .. 91 115 .. 91 116 .. 0.97 4 ! 20.6 0.0 2.9e-07 0.00058 2 31 .] 121 149 .. 120 149 .. 0.95 5 ? 0.7 0.0 0.93 1.8e+03 6 30 .. 178 202 .. 178 203 .. 0.82 6 ! 24.9 0.0 1.1e-08 2.2e-05 4 30 .. 210 235 .. 207 236 .. 0.94 7 ! 21.9 0.1 1.1e-07 0.00021 5 31 .] 244 269 .. 242 269 .. 0.96 8 ! 17.4 0.0 3.3e-06 0.0065 3 29 .. 275 300 .. 273 302 .. 0.92 9 ? 5.9 0.0 0.019 37 3 30 .. 362 391 .. 360 392 .. 0.86 10 ! 18.5 0.0 1.4e-06 0.0027 3 31 .] 398 425 .. 396 425 .. 0.94 11 ! 15.9 0.0 1e-05 0.02 2 30 .. 430 457 .. 429 458 .. 0.95 12 ? 3.2 0.0 0.14 2.8e+02 6 23 .. 493 510 .. 493 516 .. 0.85 13 ! 24.9 0.0 1.2e-08 2.3e-05 3 30 .. 524 550 .. 522 551 .. 0.93 14 ! 19.3 0.1 7.6e-07 0.0015 5 30 .. 559 583 .. 557 584 .. 0.93 15 ! 18.3 0.0 1.6e-06 0.0031 3 29 .. 590 615 .. 588 617 .. 0.93 16 ? -2.2 0.0 8 1.6e+04 1 17 [. 621 636 .. 621 643 .. 0.68 17 ! 26.5 0.1 3.4e-09 6.6e-06 3 31 .] 677 704 .. 675 704 .. 0.94 18 ! 16.3 0.1 7.5e-06 0.015 5 31 .] 712 737 .. 712 737 .. 0.96 19 ! 15.4 0.0 1.5e-05 0.029 3 29 .. 743 768 .. 741 770 .. 0.87 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.088 Ank_3 6 LhlAarngrleivklLleklgadin 30 L+ A+rng+++ v+ +++ + ++n FUN_001354-T1 24 LFEACRNGDVTKVRRIVN-TNSNVN 47 788*******99****99.666665 PP == domain 2 score: 23.5 bits; conditional E-value: 3.2e-08 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa +gr ++v++Ll+ +gad++ FUN_001354-T1 57 SPLHFAAGFGRKDVVEYLLQ-FGADVH 82 8*******************.****98 PP == domain 3 score: 22.1 bits; conditional E-value: 9.5e-08 Ank_3 5 pLhlAarngrleivklLleklgadin 30 pLh A+++g+ e+v+ Ll+ +gad+n FUN_001354-T1 91 PLHNACSFGHAEVVRILLR-HGADPN 115 9******************.****99 PP == domain 4 score: 20.6 bits; conditional E-value: 2.9e-07 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 ++tpLh Aa g+++++ +Ll+ +gad+n+ FUN_001354-T1 121 NYTPLHEAAVKGKVDVCVVLLQ-HGADPNI 149 79********************.*****96 PP == domain 5 score: 0.7 bits; conditional E-value: 0.93 Ank_3 6 LhlAarngrle.ivklLleklgadin 30 L Aar+g+ e ++ lL l+++++ FUN_001354-T1 178 LLEAARSGNEEkLMSLLTP-LNVNCH 202 677*******989999988.777765 PP == domain 6 score: 24.9 bits; conditional E-value: 1.1e-08 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 tpLhlAa ++r+ +v+lLl+ +gad++ FUN_001354-T1 210 TPLHLAAGYNRVRVVQLLLQ-HGADVH 235 9*******************.****98 PP == domain 7 score: 21.9 bits; conditional E-value: 1.1e-07 Ank_3 5 pLhlAarngrleivklLleklgadina 31 pLh A+++g++++ +lL++ +ga++na FUN_001354-T1 244 PLHNACSYGHYDVTELLIK-HGASVNA 269 9******************.****996 PP == domain 8 score: 17.4 bits; conditional E-value: 3.3e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 tpLh Aa+ +r+e++ lLl +gad+ FUN_001354-T1 275 FTPLHEAASKARVEVCSLLLA-HGADP 300 69************9999999.***98 PP == domain 9 score: 5.9 bits; conditional E-value: 0.019 Ank_3 3 ntpLhlAarngrl...eivklLleklgadin 30 ++ LhlA+++ ++ ++++Ll+ +gad n FUN_001354-T1 362 ESSLHLAVSSVCPkrkSAIEVLLK-KGADTN 391 678**********76548******.***987 PP == domain 10 score: 18.5 bits; conditional E-value: 1.4e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadina 31 tpLh+A + +l++v+lL++ +ga++na FUN_001354-T1 398 LTPLHIASEKSHLDAVELLIK-NGAKVNA 425 69*******************.****996 PP == domain 11 score: 15.9 bits; conditional E-value: 1e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 g+t+Lh Aa g+ +++ Ll +gadi FUN_001354-T1 430 GETALHRAAAAGQTSACRILLS-HGADIS 457 99********************.****96 PP == domain 12 score: 3.2 bits; conditional E-value: 0.14 Ank_3 6 LhlAarngrleivklLle 23 L Aar+g++e+vk L+ FUN_001354-T1 493 LLEAARSGDMEVVKKLCT 510 678***********9986 PP == domain 13 score: 24.9 bits; conditional E-value: 1.2e-08 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 tpLh+Aa ++r+ +v++Ll+ +gad++ FUN_001354-T1 524 STPLHFAAGYNRVGVVEYLLQ-NGADVH 550 59*******************.****98 PP == domain 14 score: 19.3 bits; conditional E-value: 7.6e-07 Ank_3 5 pLhlAarngrleivklLleklgadin 30 pLh A+++g++e+++lL++ +ga +n FUN_001354-T1 559 PLHNACSYGHYEVAELLVK-HGAVVN 583 9******************.999777 PP == domain 15 score: 18.3 bits; conditional E-value: 1.6e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 tpLh A g++ei++lLl+ +gad+ FUN_001354-T1 590 FTPLHEASAKGKFEICRLLLK-HGADP 615 69*******************.****8 PP == domain 16 score: -2.2 bits; conditional E-value: 8 Ank_3 1 dgntpLhlAarngrlei 17 dg+tpL ++ g+ ++ FUN_001354-T1 621 DGQTPLD-LVKDGDTDV 636 6999998.566666665 PP == domain 17 score: 26.5 bits; conditional E-value: 3.4e-09 Ank_3 3 ntpLhlAarngrleivklLleklgadina 31 tpLhlAa ++++e+++ Lle +gad+na FUN_001354-T1 677 STPLHLAAGYNHFEVAEHLLE-NGADVNA 704 69*******************.*****96 PP == domain 18 score: 16.3 bits; conditional E-value: 7.5e-06 Ank_3 5 pLhlAarngrleivklLleklgadina 31 pLh A ++g+++i+ lL++ ++ d+na FUN_001354-T1 712 PLHNASSYGHVDIASLLIK-HNTDVNA 737 9******************.9***996 PP == domain 19 score: 15.4 bits; conditional E-value: 1.5e-05 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 tpLh Aa gr +++ lLl +gad+ FUN_001354-T1 743 FTPLHEAAQKGRTQLCALLLA-HGADP 768 59************7777777.****8 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 7.2e-06 0.014 21 70 .. 23 79 .. 19 85 .. 0.90 2 ! 20.8 0.0 1.8e-07 0.00036 50 127 .. 92 163 .. 80 167 .. 0.84 3 ! 13.8 0.0 2.6e-05 0.052 46 107 .. 174 230 .. 166 243 .. 0.76 4 ! 12.1 0.0 8.5e-05 0.17 50 115 .. 245 303 .. 233 321 .. 0.81 5 ? 2.2 0.1 0.095 1.9e+02 36 107 .. 351 419 .. 314 429 .. 0.65 6 ? 3.7 0.5 0.032 63 19 69 .. 398 453 .. 384 457 .. 0.78 7 ! 14.2 0.0 1.9e-05 0.038 25 107 .. 465 545 .. 457 556 .. 0.77 8 ! 16.8 0.0 3e-06 0.0058 50 127 .. 560 631 .. 547 638 .. 0.84 9 ? 5.3 0.0 0.011 21 20 69 .. 644 699 .. 634 707 .. 0.61 10 ! 17.1 0.1 2.5e-06 0.0049 19 128 .. 677 785 .. 672 801 .. 0.87 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.2e-06 Ank_KRIT1 21 eLrkaaakGdeetvariLnvrekvddpes.......lvaAakgGheevlqlLlalGk 70 eL +a+ +Gd++ v ri+n +++v+ ++ l+ Aa G+++v+++Ll+ G FUN_001354-T1 23 ELFEACRNGDVTKVRRIVNTNSNVNLRDTagrksspLHFAAGFGRKDVVEYLLQFGA 79 788999*****************9977767788899******************995 PP == domain 2 score: 20.8 bits; conditional E-value: 1.8e-07 Ank_KRIT1 50 lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeefdptrr.lkgetyleiare 127 l++A+ Gh ev+++Ll G adp+ s ++ tPl a +++++v +ll+ ++ dp++r + g+t l++a+ FUN_001354-T1 92 LHNACSFGHAEVVRILLRHG-ADPN-----SRDNWNYTPLHEAAVKGKVDVCVVLLQ-HGADPNIRnTDGKTALDVAET 163 899***************99.5676.....4445567***999999*****999885.578999888********9986 PP == domain 3 score: 13.8 bits; conditional E-value: 2.6e-05 Ank_KRIT1 46 dpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 ++e l+ Aa+ G ee l Ll +++ + stPl a G ++++v++lll++ FUN_001354-T1 174 KKEELLEAARSGNEEKLMSLLTPLNVNCH-----ASDGRKSTPLHLAAGYNRVRVVQLLLQH 230 56788899999999888888877677666.....4567789999777788999999999976 PP == domain 4 score: 12.1 bits; conditional E-value: 8.5e-05 Ank_KRIT1 50 lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeefdptrr 115 l++A+ +Gh +v++lL++ G v+ ++ + tPl a +++++v +lll + + dpt FUN_001354-T1 245 LHNACSYGHYDVTELLIKHGA------SVNAMDLWQFTPLHEAASKARVEVCSLLLAH-GADPTLL 303 899****************96......4667888899*******************87.4577655 PP == domain 5 score: 2.2 bits; conditional E-value: 0.095 Ank_KRIT1 36 riLnvrekvddpeslvaAakg...GheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 +i+n ++ + sl+ A +++++++Ll++G d + + ++++ tPl a + +l+ ++ll+++ FUN_001354-T1 351 EIINFQHPLTLESSLHLAVSSvcpKRKSAIEVLLKKGA-DTN---L--QNKDSLTPLHIASEKSHLDAVELLIKN 419 46666666655556666654422245677888888873.444...3..357888999999999999999999865 PP == domain 6 score: 3.7 bits; conditional E-value: 0.032 Ank_KRIT1 19 deeLrkaaakGdeetvariLnvrekvddpes.....lvaAakgGheevlqlLlalG 69 + L+ a++k ++v+ +++ kv+ ++ l+ Aa +G++++ ++Ll G FUN_001354-T1 398 LTPLHIASEKSHLDAVELLIKNGAKVNAVDAlgetaLHRAAAAGQTSACRILLSHG 453 45677888888888888888888888888877777799999999999999999988 PP == domain 7 score: 14.2 bits; conditional E-value: 1.9e-05 Ank_KRIT1 25 aaakGdeetvariLnvrekvddpes...lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 +aa+ +e v++iL+ ++ l+ Aa+ G ev++ L +++ ++l+ +stPl a G +++ v++ ll++ FUN_001354-T1 465 TAAEVASEPVQKILQEDPPSTGSDVekqLLEAARSGDMEVVKKLCTPQTVNA-----RDLEGRHSTPLHFAAGYNRVGVVEYLLQN 545 5777788999999999866533332335**************9976554444.....577999*****999999*******99964 PP == domain 8 score: 16.8 bits; conditional E-value: 3e-06 Ank_KRIT1 50 lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeefdptrr.lkgetyleiare 127 l++A+ +Gh ev +lL++ G + v+ ++ tPl a +++ ++ +lll++ + dp+++ g+t+l++ ++ FUN_001354-T1 560 LHNACSYGHYEVAELLVKHGAV------VNVADLWKFTPLHEASAKGKFEICRLLLKH-GADPQKKtRDGQTPLDLVKD 631 899*****************86......444556678*******************87.56998886889999999875 PP == domain 9 score: 5.3 bits; conditional E-value: 0.011 Ank_KRIT1 20 eeLrkaaakGdeetvariLn.vrekvddpes.....lvaAakgGheevlqlLlalG 69 L +aa+kG+ + v+++ + ++ d++ l+ Aa + h ev + Ll+ G FUN_001354-T1 644 AALLDAAKKGNLTRVMKLSTpENINCRDTQGrnstpLHLAAGYNHFEVAEHLLENG 699 55666777777777776532122233333334445577777777777777777766 PP == domain 10 score: 17.1 bits; conditional E-value: 2.5e-06 Ank_KRIT1 19 deeLrkaaakGdeetvariLnvrekvddpes.....lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqee 109 ++ L+ aa+ e+++++L+ +v+ ++ l++A+ +Gh ++ +lL++ + d v+ ++ + tPl a ++++++ lll + + FUN_001354-T1 677 STPLHLAAGYNHFEVAEHLLENGADVNAQDKgglipLHNASSYGHVDIASLLIK---HNTD---VNATDRWLFTPLHEAAQKGRTQLCALLLAH-G 765 56788899999999999****999999888788999****************95...6888...7788999*********************87.6 PP Ank_KRIT1 110 fdptrr.lkgetyleiarer 128 dpt + ++g+t l++a FUN_001354-T1 766 ADPTMKnQEGQTALDLATAE 785 7999888********99765 PP >> PARP Poly(ADP-ribose) polymerase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.6 0.1 5.3e-24 1e-20 22 146 .. 990 1130 .. 968 1136 .. 0.88 2 ! 10.0 0.1 0.00032 0.63 176 198 .. 1133 1155 .. 1127 1156 .. 0.86 Alignments for each domain: == domain 1 score: 74.6 bits; conditional E-value: 5.3e-24 PARP 22 klelveifrveregeaerfeekka........lrnrrlLwHGsrltnvagilsqGLriappeapvtGymfGkGvYfaddaskSanYckaseaeg 107 ++++v+i+rv ++ +++++ + +n+r+L+HGs ++++il++G+ + + a + G mfG G+Yfa+ +skS +Y++ g FUN_001354-T1 990 SYNIVKIQRVINKRLWDKYVYRRRevaeanhnHSNERMLFHGS--AFIHAILQKGF--DERHAYI-GGMFGAGIYFAENSSKSNQYVYG-IGGG 1077 689***************98877778999887888*******9..58*********..8899988.99********************6.9999 PP PARP 108 sgl..............llLaeValGdileLlkadyaekkkkgkksvkgkgkk 146 sg+ llL++ValG+ ++a + ++++g +sv+g+ ++ FUN_001354-T1 1078 SGCalhkdkscyicerqLLLCRVALGKPFYHFAAAKIAHAPPGHHSVIGRPSS 1130 999************************666666666788999*****998765 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00032 PARP 176 leyneyvVydkeqvrlkYLlkvk 198 l eyvVy eq++++YL+ +k FUN_001354-T1 1133 LSFAEYVVYRGEQAYPEYLISYK 1155 56689***************997 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.4 0.5 1.6e-17 3.1e-14 8 64 .. 875 930 .. 872 931 .. 0.97 Alignments for each domain: == domain 1 score: 53.4 bits; conditional E-value: 1.6e-17 SAM_2 8 svaeWLrsigleqykdnFkdagitgaelllrlteedLkelGitsvghrkkilkkiqe 64 +v+e+L++i+l+ kd+F++ +i+ ++l + +e+Lke+Gi+++ghr+kilk+++e FUN_001354-T1 875 NVGEFLDNIQLKNLKDIFEQEEISW-DVLVDMGHEELKEIGIHAYGHRHKILKAVKE 930 79***********************.****************************986 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.9 0.0 0.0081 16 44 88 .. 68 112 .. 49 119 .. 0.80 2 ? 0.4 0.0 0.39 7.6e+02 30 75 .. 120 165 .. 115 181 .. 0.79 3 ? -0.2 0.0 0.59 1.2e+03 34 88 .. 178 232 .. 160 238 .. 0.56 4 ? 5.5 0.0 0.01 20 35 61 .. 245 271 .. 237 301 .. 0.80 5 ! 8.6 0.1 0.0011 2.2 38 94 .. 372 427 .. 358 454 .. 0.75 6 ? 0.0 0.0 0.52 1e+03 28 68 .. 427 467 .. 421 518 .. 0.62 7 ? 5.4 0.0 0.011 23 36 88 .. 528 580 .. 493 581 .. 0.78 8 ! 6.8 0.0 0.0042 8.3 35 92 .. 560 617 .. 557 648 .. 0.77 9 ! 6.6 0.0 0.0047 9.2 38 89 .. 683 734 .. 669 771 .. 0.69 10 ? 0.9 0.0 0.27 5.3e+02 35 89 .. 713 767 .. 710 791 .. 0.69 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0081 ANK_LRRK2 44 vvmaEcllllgadvnkktktesl.iyqvCErgsplelvelllssgv 88 ++E ll++gadv k + + + + C g+ +e+v +ll++g+ FUN_001354-T1 68 KDVVEYLLQFGADVHAKDDGGLIpLHNACSFGH-AEVVRILLRHGA 112 568999********9887654443467888776.899999999987 PP == domain 2 score: 0.4 bits; conditional E-value: 0.39 ANK_LRRK2 30 lkeklLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgs 75 +++ L++a ++g+v + ll+ gad n ++ + +v E FUN_001354-T1 120 WNYTPLHEAAVKGKVDVCVVLLQHGADPNIRNTDGKTALDVAETSA 165 56777999999999*************9987776666667766655 PP == domain 3 score: -0.2 bits; conditional E-value: 0.59 ANK_LRRK2 34 lLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgv 88 lLe a + ++ + l l + + ++s + + +++v+lll++g+ FUN_001354-T1 178 LLEAARSGNEEKLMSLLTPLNVNCHASDGRKSTPLHLAAGYNRVRVVQLLLQHGA 232 4444444445555555555555555555555555555555566666666666664 PP == domain 4 score: 5.5 bits; conditional E-value: 0.01 ANK_LRRK2 35 LekaCeegdvvmaEcllllgadvnkkt 61 L++aC+ g+ ++E l++ ga vn FUN_001354-T1 245 LHNACSYGHYDVTELLIKHGASVNAMD 271 789*********************865 PP == domain 5 score: 8.6 bits; conditional E-value: 0.0011 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvrEqdlr 94 +C +++++ +E ll+ gad n ++k++ ++ +s+l+ vell+++g++ + + FUN_001354-T1 372 VCPKRKSA-IEVLLKKGADTNLQNKDSLTPLHIASEKSHLDAVELLIKNGAKVNAVD 427 56655554.69**********998887777888888889***********9987764 PP == domain 6 score: 0.0 bits; conditional E-value: 0.52 ANK_LRRK2 28 sdlkeklLekaCeegdvvmaEcllllgadvnkktktesliy 68 + l e+ L++a + g++ ll gad+ ++ + FUN_001354-T1 427 DALGETALHRAAAAGQTSACRILLSHGADISLRSFQGHTAA 467 66777888999999999999999999999976665554444 PP == domain 7 score: 5.4 bits; conditional E-value: 0.011 ANK_LRRK2 36 ekaCeegdvvmaEcllllgadvnkktktesl.iyqvCErgsplelvelllssgv 88 + a + v ++E ll+ gadv k k + + + C g+ e++ell+++g+ FUN_001354-T1 528 HFAAGYNRVGVVEYLLQNGADVHAKDKGGLVpLHNACSYGH-YEVAELLVKHGA 580 556666778899**********9998865544678898887.999999999986 PP == domain 8 score: 6.8 bits; conditional E-value: 0.0042 ANK_LRRK2 35 LekaCeegdvvmaEcllllgadvnkktktesl.iyqvCErgsplelvelllssgvrEqd 92 L++aC+ g+ +aE l++ ga vn + + + + +g+ e+ lll++g+ q+ FUN_001354-T1 560 LHNACSYGHYEVAELLVKHGAVVNVADLWKFTpLHEASAKGK-FEICRLLLKHGADPQK 617 789********************9876544330455555555.8999999999987765 PP == domain 9 score: 6.6 bits; conditional E-value: 0.0047 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvr 89 a +++ +aE ll+ gadvn + k + + ++++++ ll+++ + FUN_001354-T1 683 AAGYNHFEVAEHLLENGADVNAQDKGGLIPLHNASSYGHVDIASLLIKHNTD 734 56668899*************9988766656667777777777777776544 PP == domain 10 score: 0.9 bits; conditional E-value: 0.27 ANK_LRRK2 35 LekaCeegdvvmaEcllllgadvnkktktesl.iyqvCErgsplelvelllssgvr 89 L++a + g+v +a l++ +dvn + + + + +++ ++l lll++g+ FUN_001354-T1 713 LHNASSYGHVDIASLLIKHNTDVNATDRWLFTpLHEAA-QKGRTQLCALLLAHGAD 767 56777888999999999999999998775433133444.44558999999998863 PP >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.0 0.4 1.7e-15 3.4e-12 7 61 .. 875 929 .. 873 931 .. 0.97 Alignments for each domain: == domain 1 score: 47.0 bits; conditional E-value: 1.7e-15 SAM_1 7 dVgeWLesiglgqYadsFrkgyidgetLlqlteddLeklgvtllgHrkkIlsaiq 61 Vge+L+ i+l+ +d F++++i+++ L ++ ++L+++g+ gHr+kIl+a++ FUN_001354-T1 875 NVGEFLDNIQLKNLKDIFEQEEISWDVLVDMGHEELKEIGIHAYGHRHKILKAVK 929 59**************************************************997 PP >> Amidohydro_1 Amidohydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 0.46 9.1e+02 178 220 .. 91 143 .. 77 166 .. 0.71 2 ? 3.3 0.1 0.028 55 161 220 .. 233 296 .. 205 328 .. 0.74 3 ? -4.0 0.0 4.6 9.1e+03 205 245 .. 379 423 .. 360 430 .. 0.63 4 ? -1.1 0.0 0.61 1.2e+03 164 212 .. 550 596 .. 521 658 .. 0.73 5 ? 13.4 0.2 2.5e-05 0.048 149 247 .. 689 791 .. 680 801 .. 0.87 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.46 Amidohydro_1 178 hlevaeslgllddiklilahgvhls..pt.elellaehlkgagva.......h 220 +l++a s+g++++++++l+hg + ++ +++ l+e + + +v h FUN_001354-T1 91 PLHNACSFGHAEVVRILLRHGADPNsrDNwNYTPLHEAAVKGKVDvcvvllqH 143 7899999***************9996422566666666655555544555554 PP == domain 2 score: 3.3 bits; conditional E-value: 0.028 Amidohydro_1 161 evedaeaafggtiehgthlevaeslgllddiklilahgvhlspt...elellaehlkgagva.......h 220 +v +a++++g +l++a s+g+ d++ l+++hg + ++ ++ l+e + +a+v h FUN_001354-T1 233 DV-HAKDKGG---LV--PLHNACSYGHYDVTELLIKHGASVNAMdlwQFTPLHEAASKARVEvcslllaH 296 44.5666666...67..9999*********************5557899999999988888755665552 PP == domain 3 score: -4.0 bits; conditional E-value: 4.6 Amidohydro_1 205 elellaehlkgagva....hcpfsnsklrsgrealrkaleeGvkv 245 +e+l +++ ++++ + p +s+++a++ ++++G+kv FUN_001354-T1 379 AIEVLLKKGADTNLQnkdsLTPLHIASEKSHLDAVELLIKNGAKV 423 455555554444444555566666666778888888888888775 PP == domain 4 score: -1.1 bits; conditional E-value: 0.61 Amidohydro_1 164 daeaafggtiehgthlevaeslgllddiklilahgvhlspt...elellaeh 212 +a++++g +l++a s+g+ +++ l+++hg + + +++ l+e FUN_001354-T1 550 HAKDKGG---LV--PLHNACSYGHYEVAELLVKHGAVVNVAdlwKFTPLHEA 596 5555555...66..89999999999999999999999995544555555554 PP == domain 5 score: 13.4 bits; conditional E-value: 2.5e-05 Amidohydro_1 149 lpvaiHaletkgevedaeaafggtiehgthlevaeslgllddiklilahgvhlspt...elellaehlkgagva.......hcpfsnsklrsgrea 234 va H+le+ ++v +a++++g +l++a s+g+ d++ l+++h++ + +t ++ l+e +++ + h +++ +k ++g a FUN_001354-T1 689 FEVAEHLLENGADV-NAQDKGG---LI--PLHNASSYGHVDIASLLIKHNTDVNATdrwLFTPLHEAAQKGRTQlcalllaHGADPTMKNQEGQTA 778 67999*********.*******...66..*************************777788888888877776666699999999**********99 PP Amidohydro_1 235 lrkaleeGvkvgl 247 l a +e+vk+ l FUN_001354-T1 779 LDLATAEDVKCLL 791 9999999999876 PP >> DUF7855 DUF7855 N-terminal dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.012 24 29 59 .. 428 458 .. 420 462 .. 0.90 2 ? -2.8 0.0 4.9 9.6e+03 35 59 .. 560 584 .. 556 586 .. 0.82 3 ? 2.7 0.0 0.09 1.8e+02 35 58 .. 593 616 .. 591 620 .. 0.87 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.012 DUF7855 29 rfGRaaLleetefgAflalRLrekhgedvqv 59 +G +aL ++++ g a+R+ hg+d+ + FUN_001354-T1 428 ALGETALHRAAAAGQTSACRILLSHGADISL 458 6899************************976 PP == domain 2 score: -2.8 bits; conditional E-value: 4.9 DUF7855 35 LleetefgAflalRLrekhgedvqv 59 L ++ +g + L khg+ v+v FUN_001354-T1 560 LHNACSYGHYEVAELLVKHGAVVNV 584 66778899999999999***99987 PP == domain 3 score: 2.7 bits; conditional E-value: 0.09 DUF7855 35 LleetefgAflalRLrekhgedvq 58 L e+++ g f +RL khg+d q FUN_001354-T1 593 LHEASAKGKFEICRLLLKHGADPQ 616 56788899************9966 PP >> NTF2_4 NTF2-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 9.1 1.8e+04 14 38 .. 24 47 .. 22 49 .. 0.75 2 ? 1.0 0.0 0.4 7.9e+02 12 36 .. 176 200 .. 170 207 .. 0.85 3 ? 0.2 0.0 0.73 1.4e+03 13 36 .. 331 354 .. 326 359 .. 0.86 4 ? 3.7 0.0 0.061 1.2e+02 6 36 .. 485 515 .. 480 522 .. 0.86 5 ? -0.2 0.0 0.94 1.8e+03 16 36 .. 648 668 .. 644 680 .. 0.88 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 9.1 NTF2_4 14 fkkAiksgdlfkvlkflsPqkgntn 38 + +A ++gd+ kv ++ ++n n FUN_001354-T1 24 LFEACRNGDVTKVRRIVN-TNSNVN 47 66789999***9998877.666655 PP == domain 2 score: 1.0 bits; conditional E-value: 0.4 NTF2_4 12 kkfkkAiksgdlfkvlkflsPqkgn 36 +++ +A +sg+ +k++ +l+P + n FUN_001354-T1 176 EELLEAARSGNEEKLMSLLTPLNVN 200 5788999**************9877 PP == domain 3 score: 0.2 bits; conditional E-value: 0.73 NTF2_4 13 kfkkAiksgdlfkvlkflsPqkgn 36 ++ +A ks d k++k+++P +n FUN_001354-T1 331 QLLEAAKSCDSAKLKKHITPEIIN 354 677899**************7655 PP == domain 4 score: 3.7 bits; conditional E-value: 0.061 NTF2_4 6 vakqffkkfkkAiksgdlfkvlkflsPqkgn 36 ++ + k++ +A +sgd++ v+k+ +Pq+ n FUN_001354-T1 485 TGSDVEKQLLEAARSGDMEVVKKLCTPQTVN 515 567788999*******************987 PP == domain 5 score: -0.2 bits; conditional E-value: 0.94 NTF2_4 16 kAiksgdlfkvlkflsPqkgn 36 A k+g+l +v+k+ +P ++n FUN_001354-T1 648 DAAKKGNLTRVMKLSTPENIN 668 6889*************9987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1166 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 612 (0.0239577); expected 510.9 (0.02) Passed bias filter: 554 (0.0216872); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.50u 0.37s 00:00:00.87 Elapsed: 00:00:00.42 # Mc/sec: 11216.23 // Query: FUN_001355-T1 [L=629] Description: FUN_001355 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-57 195.1 0.1 8.9e-57 192.2 0.1 2.1 1 SET_TTL Tubulin tyrosine ligase SET-like domain 7.9e-53 180.0 0.0 1.2e-52 179.4 0.0 1.2 1 TTL Tubulin-tyrosine ligase family Domain annotation for each model (and alignments): >> SET_TTL Tubulin tyrosine ligase SET-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 192.2 0.1 7e-61 8.9e-57 8 174 .. 41 226 .. 36 227 .. 0.88 Alignments for each domain: == domain 1 score: 192.2 bits; conditional E-value: 7e-61 SET_TTL 8 elslkvvvtresglqasdptsiflvdhawtyrveharqqleqvpgllkrmaslmgvdfh....gevpdeevvelvleemwkynqtyqlsq...... 93 e l+v vtre+g+++sdp+ +fl+dhawty v+ ar+ql+ +pgl +rma lmg+ e+++e e+++e+mw +nq y+l FUN_001355-T1 41 EGDLRVFVTREEGIETSDPNCVFLIDHAWTYEVNYAREQLKTIPGLAERMALLMGLASTdediSEISQEVLTEKIFEKMWSFNQNYHLKVvtagit 136 55679**************************************************98762222567888889***************976344343 PP SET_TTL 94 .........gsaeekvpvwyildefgsrvqhsdepscavaplfyikqqlaytvlwplrdleegdevtrdyaygetdplvrkcrllpwipa 174 ee+ p+wyi+defgs ++hs +ps+ava lfy++ ++++++wplrd++ g+e+tr+y g dplvr c llpw p+ FUN_001355-T1 137 rnenhdrssSGDEEHTPLWYIMDEFGSCIKHSVDPSFAVAMLFYVPLGVSFSIMWPLRDMAYGEEATRNYVNGVEDPLVRDCCLLPWFPD 226 444444332335899************************************************************************997 PP >> TTL Tubulin-tyrosine ligase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 179.4 0.0 9.5e-57 1.2e-52 6 281 .. 328 617 .. 323 625 .. 0.96 Alignments for each domain: == domain 1 score: 179.4 bits; conditional E-value: 9.5e-57 TTL 6 ekvqalnhfpesaeitrkdllvknlkrqkkkrekk........fdflprtfilpteleefveafeeees....nlwIvKpsasarGrgivvtnklk 89 e+ + +n+fp+++++t kdll+ + + + ++++ ++lp tf+l+ el+ fv++ ++++ n+wI+Kp++ ar ++ +vt++l+ FUN_001355-T1 328 ENGKFINQFPNESCLTCKDLLAAVCQSAAPSESNEgddllrrgPEWLPVTFNLNLELPLFVDHYLKRKKrgldNHWICKPWNLARAIDSHVTSNLN 423 347889***************99998888777777789*****9***********************999************************** PP TTL 90 qilkqsqkeplvvqkYierPLLidg.....rKFDlRlyvlvtsvnpLrvYvYkegllRfasvkYskslsdlddeevHLtNysiqkkskyslneesn 180 il+ ++++p+vv+kYie+P+L+d+ +KFD R+ vl+ s +pL + v k ++lRfa++++s l+++d +++H+t++++++ e+ FUN_001355-T1 424 YILRLRETGPKVVCKYIEKPVLFDRegigrVKFDVRYLVLISSAKPLVIHVDKVFWLRFANQPFS--LDSFDVYSKHFTVMNYKDS-------ENL 510 *****************************************************************..9****************99.......899 PP TTL 181 ekkgekwslqelekyleevdkeeiwseiesiiiktilaaeveasrrnverrkncfelyGfDill......deelkpwLlEvNasPslksttkldae 270 + ++ ++++ +ek++++ +++++ +i+++ + +++aa + s++++ + ++++ y++D++l +e+ p++lE N+ P+++++++++++ FUN_001355-T1 511 KTMHPDEFIALFEKQYPNHRWSDVEVKIFKMLQGVFEAAISDSSPKTLIPCTQSRAFYAVDLMLkwaedgTDEIVPQVLEMNFGPDCERACRYYPN 606 99*************************************9999***********************9999999*********************** PP TTL 271 lkeqliedvln 281 +++ +++ ++ FUN_001355-T1 607 FFNFIFSLLFL 617 *****998775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (629 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 746 (0.0292034); expected 510.9 (0.02) Passed bias filter: 676 (0.0264631); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6124.71 // Query: FUN_001355-T2 [L=625] Description: FUN_001355 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-57 195.1 0.1 8.8e-57 192.2 0.1 2.1 1 SET_TTL Tubulin tyrosine ligase SET-like domain 7.9e-53 180.0 0.0 1.2e-52 179.5 0.0 1.2 1 TTL Tubulin-tyrosine ligase family Domain annotation for each model (and alignments): >> SET_TTL Tubulin tyrosine ligase SET-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 192.2 0.1 6.9e-61 8.8e-57 8 174 .. 37 222 .. 32 223 .. 0.88 Alignments for each domain: == domain 1 score: 192.2 bits; conditional E-value: 6.9e-61 SET_TTL 8 elslkvvvtresglqasdptsiflvdhawtyrveharqqleqvpgllkrmaslmgvdfh....gevpdeevvelvleemwkynqtyqlsq...... 93 e l+v vtre+g+++sdp+ +fl+dhawty v+ ar+ql+ +pgl +rma lmg+ e+++e e+++e+mw +nq y+l FUN_001355-T2 37 EGDLRVFVTREEGIETSDPNCVFLIDHAWTYEVNYAREQLKTIPGLAERMALLMGLASTdediSEISQEVLTEKIFEKMWSFNQNYHLKVvtagit 132 55679**************************************************98762222567888889***************976344343 PP SET_TTL 94 .........gsaeekvpvwyildefgsrvqhsdepscavaplfyikqqlaytvlwplrdleegdevtrdyaygetdplvrkcrllpwipa 174 ee+ p+wyi+defgs ++hs +ps+ava lfy++ ++++++wplrd++ g+e+tr+y g dplvr c llpw p+ FUN_001355-T2 133 rnenhdrssSGDEEHTPLWYIMDEFGSCIKHSVDPSFAVAMLFYVPLGVSFSIMWPLRDMAYGEEATRNYVNGVEDPLVRDCCLLPWFPD 222 444444332335899************************************************************************997 PP >> TTL Tubulin-tyrosine ligase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 179.5 0.0 9.4e-57 1.2e-52 6 281 .. 324 613 .. 319 621 .. 0.96 Alignments for each domain: == domain 1 score: 179.5 bits; conditional E-value: 9.4e-57 TTL 6 ekvqalnhfpesaeitrkdllvknlkrqkkkrekk........fdflprtfilpteleefveafeeees....nlwIvKpsasarGrgivvtnklk 89 e+ + +n+fp+++++t kdll+ + + + ++++ ++lp tf+l+ el+ fv++ ++++ n+wI+Kp++ ar ++ +vt++l+ FUN_001355-T2 324 ENGKFINQFPNESCLTCKDLLAAVCQSAAPSESNEgddllrrgPEWLPVTFNLNLELPLFVDHYLKRKKrgldNHWICKPWNLARAIDSHVTSNLN 419 347889***************99998888777777789*****9***********************999************************** PP TTL 90 qilkqsqkeplvvqkYierPLLidg.....rKFDlRlyvlvtsvnpLrvYvYkegllRfasvkYskslsdlddeevHLtNysiqkkskyslneesn 180 il+ ++++p+vv+kYie+P+L+d+ +KFD R+ vl+ s +pL + v k ++lRfa++++s l+++d +++H+t++++++ e+ FUN_001355-T2 420 YILRLRETGPKVVCKYIEKPVLFDRegigrVKFDVRYLVLISSAKPLVIHVDKVFWLRFANQPFS--LDSFDVYSKHFTVMNYKDS-------ENL 506 *****************************************************************..9****************99.......899 PP TTL 181 ekkgekwslqelekyleevdkeeiwseiesiiiktilaaeveasrrnverrkncfelyGfDill......deelkpwLlEvNasPslksttkldae 270 + ++ ++++ +ek++++ +++++ +i+++ + +++aa + s++++ + ++++ y++D++l +e+ p++lE N+ P+++++++++++ FUN_001355-T2 507 KTMHPDEFIALFEKQYPNHRWSDVEVKIFKMLQGVFEAAISDSSPKTLIPCTQSRAFYAVDLMLkwaedgTDEIVPQVLEMNFGPDCERACRYYPN 602 99*************************************9999***********************9999999*********************** PP TTL 271 lkeqliedvln 281 +++ +++ ++ FUN_001355-T2 603 FFNFIFSLLFL 613 *****998775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (625 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 724 (0.0283421); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.40u 0.37s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5991.83 // Query: FUN_001356-T1 [L=847] Description: FUN_001356 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-198 660.5 0.0 2.9e-154 514.5 0.0 2.0 2 Aldedh Aldehyde dehydrogenase family 8.2e-06 25.9 0.2 6e-05 23.1 0.0 2.4 2 DUF1487 Protein of unknown function (DUF1487) ------ inclusion threshold ------ 0.022 15.1 0.2 0.28 11.5 0.0 2.7 3 DUF3659 Protein of unknown function (DUF3659) 0.076 13.7 0.0 13 6.5 0.0 3.3 3 MHB Haemophore, haem-binding 0.076 13.4 0.1 9 6.8 0.0 2.5 2 DUF5635 Family of unknown function (DUF5635) 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 Mucin_bdg Putative mucin or carbohydrate-binding module 0.17 12.4 2.3 70 4.0 0.0 3.7 4 OmdA Bacteriocin-protection, YdeI or OmpD-Associated Domain annotation for each model (and alignments): >> Aldedh Aldehyde dehydrogenase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 514.5 0.0 8e-158 2.9e-154 1 456 [. 66 509 .. 66 513 .. 0.98 2 ! 144.0 0.0 1.9e-45 7e-42 9 237 .. 584 811 .. 577 815 .. 0.95 Alignments for each domain: == domain 1 score: 514.5 bits; conditional E-value: 8e-158 Aldedh 1 wveseset.ievinPatgeviakvpaataedvdkaveaAkeafkewaklpaeeRaeilrkaadlleerkeelaelealetGkplaeara.everai 94 w ++++++ +e+ nPatge++a++ ++++ed+d+av+aA+eafk+w+klp + Ra++l+ +a+ +++++ +a le++++Gkp++e+r +v+ ++ FUN_001356-T1 66 WLKPKGRKiYESRNPATGETLASTLQGEQEDIDNAVSAAREAFKSWSKLPGHIRARYLYSIARHVQKHARLIAVLESMDNGKPIRETRDaDVQIVV 161 888889777*************************************************************************************** PP Aldedh 95 dvlryyaglaeklegetlpsskgklalvrrePlGvvgvItPWNfPlllvawkiapalaaGNtvvlKpseetpltalllaelleeaglPkgvlnvvt 190 ++l ag+a+ ++ e+ ++P+Gvvg+I+PWNfPl+l++wk++pala+GNtvvlKp++ t ltall+ae+++eaglP+gv+nv+t FUN_001356-T1 162 RHLYHHAGWAQLMDTEMR----------DWKPVGVVGAIVPWNFPLMLLCWKVCPALAMGNTVVLKPATYTRLTALLFAEICAEAGLPPGVFNVIT 247 ************998774..........468***************************************************************** PP Aldedh 191 gsgaevgealvehpdvrlvsftGStevgrkiaeaaaknlkrvtlElGGknpliVledaDldkaveaavkgaflnaGQvCtatsrllvqesiydefv 286 g+ga +g l++hpdv++v+ftGStevg+ + + a + k+++lElGGk+p++V+++aDld+ave++v ++++n+GQvC+a+srl+vqe ++++++ FUN_001356-T1 248 GNGA-FGSSLAAHPDVDKVAFTGSTEVGKVLRRLTAGSGKKLSLELGGKSPVVVFDSADLDSAVEGIVDAIWFNQGQVCSAGSRLIVQETCAKRLI 342 *885.*****************************9999********************************************************** PP Aldedh 287 eklveaakklkvgdpldedtdvGPliskkqlekvekyveeakeegaklllGgeeeaglekgyfvePtvladvtpdmriaqeEiFGPVlsvikfkde 382 +k++e+++ l++g+ ld++ d+G++++ +q + + +yveeak +ga++ + +e+g ++ Pt++++v+p ++i+ eE+FGPVl+v++f++ FUN_001356-T1 343 DKIKERMTHLRLGHCLDKSIDMGAIVDPSQKKAIAAYVEEAKRQGAEVFQSC--ASIPEDGSYYPPTLITNVQPVSKIVMEEVFGPVLTVLPFRTA 436 **************************************************99..7899************************************** PP Aldedh 383 eeaieiaNdteyGLaagvftkdleraekvaeeleaGtvwiNdsttgdaealpfgGvkqSglGreggkegleeyt 456 +e i++aN+t+yGLa++v+t++l+ a++va +++aG+vw+N ++ +da a fgG+++Sg+Gr+ggkegl ey+ FUN_001356-T1 437 KEGIALANNTKYGLAGSVWTENLSLALEVAMSIKAGSVWVNGHNLFDAAA-GFGGYRESGFGRDGGKEGLYEYV 509 **************************************************.********************996 PP == domain 2 score: 144.0 bits; conditional E-value: 1.9e-45 Aldedh 9 ievinPatgeviakvpaataedvdkaveaAkeafkewaklpaeeRaeilrkaadlleerkeelaelealetGkplaearaeveraidvlryyagla 104 +v+nP+ gevi++v++++++d+++aveaA++a ++w k a++Ra+i++ +a+ le r+ e++e ++ tG +++e+ +ev+++i+ l y+ ++a FUN_001356-T1 584 RPVLNPS-GEVIGQVAEGNRKDIRDAVEAAHKAAPGWGKRAAHNRAQIVYYMAENLELRHSEFSERLCNMTGCSIQETNKEVDMTIQRLFYWGAYA 678 5789998.9*************************************************************************************** PP Aldedh 105 eklegetlpsskgklalvrrePlGvvgvItPWNfPlllvawkiapalaaGNtvvlKpseetpltalllaelleeaglPkgvlnvvtgsgaevgeal 200 +k+ g++ ++ ++ ++eP+Gv+g+ +P +Pl+ ++ +apa++ GNtvv+ ps+ p++a+ + ++++ +lP gv+n+vtg+ + + ++l FUN_001356-T1 679 DKYGGTVQETPFYGATVKIHEPVGVIGIACPDRYPLVAFISLLAPAVIRGNTVVIIPSQSHPMVAVDMYQIFDTSDLPGGVVNIVTGDRDHLTKYL 774 ***9988777667888999***************************************************************************** PP Aldedh 201 vehpdvrlvsftGStevgrkiaeaaaknlkrvtlElG 237 +eh+dv+++ GS e + + ++a n+kr+ ++ G FUN_001356-T1 775 TEHQDVQAMWYFGSAEGSKFVEWSSAVNVKRTFVNYG 811 **************99999998889999999887766 PP >> DUF1487 Protein of unknown function (DUF1487) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 1.6e-08 6e-05 8 170 .. 298 480 .. 295 482 .. 0.73 2 ? -3.4 0.1 2.1 7.6e+03 82 119 .. 723 762 .. 715 765 .. 0.66 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 1.6e-08 DUF1487 8 mvifedgDlnsalhalvesl..kePfaegavatvlveesirdefvervrsklkpls......eevae....Hpsylkalekidelkaktisa.... 87 +v+f+++Dl+sa++ +v+++ ++ + a ++v+e+ + +++++++++ +l +++ ps +ka++ a FUN_001356-T1 298 VVVFDSADLDSAVEGIVDAIwfNQGQVCSAGSRLIVQETCAKRLIDKIKERMTHLRlghcldKSIDMgaivDPSQKKAIA-----------Ayvee 382 69****************9832455566666789******************8875211111333321111455555554...........33344 PP DUF1487 88 ..........ksesakakas...PilVldv...thsflgdgptgvvTlhtFrnakEvvkllakeplkfasvsiwneklaavyelvarlsvdvftiN 167 + +s ++++s P l+++v ++ + + v+T+ Fr+akE ++l+++ + +a s+w e+l+ + e++ ++ + +N FUN_001356-T1 383 akrqgaevfqSCASIPEDGSyypPTLITNVqpvSKIVMEEVFGPVLTVLPFRTAKEGIALANNTKYGLA-GSVWTENLSLALEVAMSIKAGSVWVN 477 44444444547888888888777999987522156677788889****************998877775.49*****************9999999 PP DUF1487 168 Cak 170 ++ FUN_001356-T1 478 GHN 480 775 PP == domain 2 score: -3.4 bits; conditional E-value: 2.1 DUF1487 82 aktisa.ksesakakasPilVldvthsflgd.gptgvvTl 119 +i++ ++ +++ P++ +d+ + f ++ p gvv + FUN_001356-T1 723 PAVIRGnTVVIIPSQSHPMVAVDMYQIFDTSdLPGGVVNI 762 5566662334456677799999999988655478888866 PP >> DUF3659 Protein of unknown function (DUF3659) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.48 1.8e+03 16 40 .. 52 76 .. 51 77 .. 0.88 2 ? -2.8 0.1 2.3 8.6e+03 18 34 .. 273 289 .. 271 295 .. 0.82 3 ? 11.5 0.0 7.8e-05 0.28 14 34 .. 586 606 .. 581 609 .. 0.91 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.48 DUF3659 16 dedGevvGrlveGdlkkLaGkkvde 40 +e+G +G+ v G+ k +G+k+ e FUN_001356-T1 52 QEHGRNFGHFVNGKWLKPKGRKIYE 76 578999*********9999999865 PP == domain 2 score: -2.8 bits; conditional E-value: 2.3 DUF3659 18 dGevvGrlveGdlkkLa 34 G+v+ rl+ G kkL FUN_001356-T1 273 VGKVLRRLTAGSGKKLS 289 58899999999999985 PP == domain 3 score: 11.5 bits; conditional E-value: 7.8e-05 DUF3659 14 vvdedGevvGrlveGdlkkLa 34 v++++Gev+G+++eG+ k++ FUN_001356-T1 586 VLNPSGEVIGQVAEGNRKDIR 606 899*************99975 PP >> MHB Haemophore, haem-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.0037 13 23 56 .. 22 55 .. 9 61 .. 0.92 2 ? -0.9 0.0 0.73 2.7e+03 19 32 .. 252 265 .. 233 271 .. 0.77 3 ? 2.5 0.0 0.063 2.3e+02 8 31 .. 759 782 .. 756 791 .. 0.79 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0037 MHB 23 LdthpdvnqvltslkgqprdqakaslrsYfeanp 56 L+++p + q++ sl+ p+++a++s++s+++++ FUN_001356-T1 22 LKKNPAIVQIFESLEYGPAPEAANSVNSWLQEHG 55 789999*************************995 PP == domain 2 score: -0.9 bits; conditional E-value: 0.73 MHB 19 tsaYLdthpdvnqv 32 ++ L++hpdv++v FUN_001356-T1 252 FGSSLAAHPDVDKV 265 455699*****986 PP == domain 3 score: 2.5 bits; conditional E-value: 0.063 MHB 8 larvvsgVaastsaYLdthpdvnq 31 + ++v+g +YL++h+dv + FUN_001356-T1 759 VVNIVTGDRDHLTKYLTEHQDVQA 782 55666777778899******9976 PP >> DUF5635 Family of unknown function (DUF5635) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 0.021 75 34 60 .. 81 107 .. 77 113 .. 0.90 2 ? 6.8 0.0 0.0025 9 2 32 .. 138 168 .. 137 173 .. 0.93 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.021 DUF5635 34 vtadavAkaLqsdkeaakeALeaarqt 60 +t +++A++Lq ++e+ +A+ aar++ FUN_001356-T1 81 ATGETLASTLQGEQEDIDNAVSAAREA 107 68899*****************99875 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0025 DUF5635 2 PvlelvskivPeaRqrDyrvAiilylLlrrp 32 vle +++ +P rD v i++ +L++++ FUN_001356-T1 138 AVLESMDNGKPIRETRDADVQIVVRHLYHHA 168 699*************************986 PP >> Mucin_bdg Putative mucin or carbohydrate-binding module # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 8.3e-05 0.3 52 108 .. 610 665 .. 604 671 .. 0.81 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 8.3e-05 Mucin_bdg 52 eklrkeveGtekqlak.vdeisfeeGdvlkifHaEpsnrLitnkdqkkvldskekens 108 e +k+++G k++a+ +i + + l+++H E s+rL ++ + +++ +ke FUN_001356-T1 610 EAAHKAAPGWGKRAAHnRAQIVYYMAENLELRHSEFSERL--CNMTGCSIQETNKEVD 665 66789999999999998899********************..6677777776666655 PP >> OmdA Bacteriocin-protection, YdeI or OmpD-Associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.095 3.5e+02 10 27 .. 20 37 .. 19 45 .. 0.92 2 ? 3.7 0.0 0.023 83 6 39 .. 95 128 .. 94 146 .. 0.73 3 ? 4.0 0.0 0.019 70 26 43 .. 369 386 .. 368 387 .. 0.93 4 ? -2.7 0.0 2.2 8.2e+03 7 35 .. 604 632 .. 599 635 .. 0.60 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.095 OmdA 10 aaLaanpeakaaFealtp 27 a+L++np+ + Fe+l + FUN_001356-T1 20 AKLKKNPAIVQIFESLEY 37 68*************976 PP == domain 2 score: 3.7 bits; conditional E-value: 0.023 OmdA 6 edleaaLaanpeakaaFealtpsyrreyllwits 39 ed+ +a a ea + + +l+ r yl+ i+ FUN_001356-T1 95 EDIDNAVSAAREAFKSWSKLPGHIRARYLYSIAR 128 6777888888888888888888888888887754 PP == domain 3 score: 4.0 bits; conditional E-value: 0.019 OmdA 26 tpsyrreyllwitsAKrp 43 ps++++++ ++++AKr+ FUN_001356-T1 369 DPSQKKAIAAYVEEAKRQ 386 59**************96 PP == domain 4 score: -2.7 bits; conditional E-value: 2.2 OmdA 7 dleaaLaanpeakaaFealtpsyrreyll 35 d+++a +a +a+ + + +r ++++ FUN_001356-T1 604 DIRDAVEAAHKAAPGWGKRAAHNRAQIVY 632 56666666666666666666666666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (847 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 830 (0.0324917); expected 510.9 (0.02) Passed bias filter: 780 (0.0305344); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.40u 0.43s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 8175.56 // Query: FUN_001357-T1 [L=182] Description: FUN_001357 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-19 70.4 0.2 3.7e-19 69.9 0.2 1.2 1 Lectin_C Lectin C-type domain 0.0015 18.7 0.0 0.0018 18.4 0.0 1.2 1 UL45 UL45 protein, carbohydrate-binding C-type lect ------ inclusion threshold ------ 0.024 15.0 0.0 0.049 14.0 0.0 1.5 1 Sec31 Protein transport protein SEC31 0.29 11.8 0.0 0.41 11.3 0.0 1.3 1 Frataxin_Cyay Frataxin-like domain Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.9 0.2 5.8e-23 3.7e-19 3 103 .. 59 170 .. 57 178 .. 0.91 Alignments for each domain: == domain 1 score: 69.9 bits; conditional E-value: 5.8e-23 Lectin_C 3 ksweeaqelCqkeggkLvsinskeenkflssllk...ksnkkfWigltdeksegtwkwedgskvnteeytnw..epnnngenedCvel........ 85 k+ ++aq++C+ g++Lv+i+s+ en+f+ +l++ s k++Wigl++e +++ w+dgs y+nw ++ n +++e C+++ FUN_001357-T1 59 KTRSDAQKFCKASGAELVKITSQSENDFVLALARekaPSLKQVWIGLQYESGPKKFYWSDGSFPV---YKNWapNEPNGNGREPCAHMwtgqtpvi 151 67789***************************99988899*************************...****99777999999************* PP Lectin_C 86 .ekssgkwndesCnsknpf 103 +ssg+wnd +C+ +++ FUN_001357-T1 152 hIRSSGYWNDLPCSINHYY 170 999**********987775 PP >> UL45 UL45 protein, carbohydrate-binding C-type lectin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.0 2.8e-07 0.0018 74 140 .. 38 105 .. 6 124 .. 0.80 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 2.8e-07 UL45 74 apCpaewiglgdsCirpigknakteeeavatCaayssklis..rsaaklLlevldvfastsaeyseekv 140 +C+++w+ ++ C+ + ++kt ++a + C+a ++l++ + + ++ +l++ + s + ++ ++ FUN_001357-T1 38 NQCDQGWVPFNSFCYLVSA-SVKTRSDAQKFCKASGAELVKitSQSENDFVLALAREKAPSLKQVWIGL 105 68*************7665.566*************999761134445566666666666666666555 PP >> Sec31 Protein transport protein SEC31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 7.6e-06 0.049 10 33 .. 143 166 .. 137 169 .. 0.85 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 7.6e-06 Sec31 10 vaSGQtPhLnkkAndGWNDLPlkv 33 + GQtP ++ WNDLP + FUN_001357-T1 143 MWTGQTPVIHIRSSGYWNDLPCSI 166 488******************876 PP >> Frataxin_Cyay Frataxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 6.5e-05 0.41 41 83 .. 75 127 .. 50 135 .. 0.71 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6.5e-05 Frataxin_Cyay 41 vLtlefenggtyvi....nkqepnkqIWlsspi.sgpkrfdyde.....egkW 83 +++++ ++++ +v+ k + +kq+W+ + sgpk+f +++ +++W FUN_001357-T1 75 LVKITSQSENDFVLalarEKAPSLKQVWIGLQYeSGPKKFYWSDgsfpvYKNW 127 556666666666663333478999****8765439*******99666643566 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 572 (0.0223919); expected 510.9 (0.02) Passed bias filter: 515 (0.0201605); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1863.37 // Query: FUN_001358-T1 [L=83] Description: FUN_001358 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-06 27.7 0.2 3.7e-06 27.5 0.2 1.1 1 QRICH1 QRICH1 domain Domain annotation for each model (and alignments): >> QRICH1 QRICH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.2 1.4e-10 3.7e-06 14 71 .. 22 81 .. 15 83 .] 0.71 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 1.4e-10 QRICH1 14 wvqeknaelekekkeelkls..rkslrlkedlLslsaeeLnyaLslfvkevrrpngekYa 71 wv + +e +k+++e ++ +++ ++ed+ ++s e L ++L++fv evr+++g++Y FUN_001358-T1 22 WVLKVFEERNKQRNEAVLKEdcSSESIIQEDIDDMSDEMLDFTLARFVAEVRKEDGQEYP 81 4444444433333333222212466779*******************************6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (83 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 846 (0.033118); expected 510.9 (0.02) Passed bias filter: 472 (0.0184772); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 839.32 // Query: FUN_001359-T1 [L=182] Description: FUN_001359 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-19 71.4 0.3 1.7e-19 71.0 0.3 1.2 1 Lectin_C Lectin C-type domain 0.00077 19.6 0.0 0.00091 19.3 0.0 1.2 1 UL45 UL45 protein, carbohydrate-binding C-type lectin-li ------ inclusion threshold ------ 0.037 14.4 0.0 0.086 13.2 0.0 1.6 1 Sec31 Protein transport protein SEC31 Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.0 0.3 2e-23 1.7e-19 3 103 .. 59 170 .. 57 178 .. 0.91 Alignments for each domain: == domain 1 score: 71.0 bits; conditional E-value: 2e-23 Lectin_C 3 ksweeaqelCqkeggkLvsinskeenkflssllk...ksnkkfWigltdeksegtwkwedgskvnteeytnw..epnnngenedCvel........ 85 k+ ++aq++C+ g++Lv+i+s+ en+f+ +l++ s k++Wigl++e + ++ w+dgs y+nw ++ n +++e C+++ FUN_001359-T1 59 KTRSDAQKFCKASGAELVKITSQSENDFVLALARekaPSVKQVWIGLQYESHPRKFYWSDGSFPV---YKNWapNEPNGNGRELCAHMwtgqtpvi 151 67789***************************99998999*************************...****9977899999************** PP Lectin_C 86 .ekssgkwndesCnsknpf 103 +ssg+wnd +C+ +++ FUN_001359-T1 152 hITSSGYWNDLPCSINHYY 170 999**********987775 PP >> UL45 UL45 protein, carbohydrate-binding C-type lectin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 1.1e-07 0.00091 74 144 .. 38 109 .. 8 126 .. 0.82 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1.1e-07 UL45 74 apCpaewiglgdsCirpigknakteeeavatCaayssklis..rsaaklLlevldvfastsaeyseekvndds 144 +C+++w+ ++ C+ + ++kt ++a + C+a ++l++ + + ++ +l++ + s + ++ +++++s FUN_001359-T1 38 NQCDHGWVPFNSFCYLVSA-SVKTRSDAQKFCKASGAELVKitSQSENDFVLALAREKAPSVKQVWIGLQYES 109 68*************7665.566**************997511445566777777777777777777766665 PP >> Sec31 Protein transport protein SEC31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 1e-05 0.086 10 33 .. 143 166 .. 138 169 .. 0.87 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1e-05 Sec31 10 vaSGQtPhLnkkAndGWNDLPlkv 33 + GQtP ++ WNDLP + FUN_001359-T1 143 MWTGQTPVIHITSSGYWNDLPCSI 166 578******************876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 568 (0.0222353); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1805.02 // Query: FUN_001360-T1 [L=180] Description: FUN_001360 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.4e-15 55.1 0.0 1.4e-06 27.6 0.1 2.0 2 Aldedh Aldehyde dehydrogenase family ------ inclusion threshold ------ 0.07 13.7 0.4 0.21 12.1 0.1 1.9 2 DUF3192 Protein of unknown function (DUF3192) 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 Mucin_bdg Putative mucin or carbohydrate-binding module Domain annotation for each model (and alignments): >> Aldedh Aldehyde dehydrogenase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.6 0.1 1.7e-10 1.4e-06 42 111 .. 11 80 .. 5 85 .. 0.94 2 ! 27.1 0.0 2.4e-10 2.1e-06 173 237 .. 80 144 .. 77 148 .. 0.92 Alignments for each domain: == domain 1 score: 27.6 bits; conditional E-value: 1.7e-10 Aldedh 42 fkewaklpaeeRaeilrkaadlleerkeelaelealetGkplaearaeveraidvlryyaglaekleget 111 +++w k a++Ra+i++ +a+ le r+ e++e ++ tG +++ea +ev+++i+ l y+ ++a+k+ g++ FUN_001360-T1 11 QESWGKRAAHNRAQIVYYMAENLELRHSEFSERLCNMTGCSIQEANREVDMTIQRLFYWGAYADKYGGTV 80 789*************************************************************998865 PP == domain 2 score: 27.1 bits; conditional E-value: 2.4e-10 Aldedh 173 aelleeaglPkgvlnvvtgsgaevgealvehpdvrlvsftGStevgrkiaeaaaknlkrvtlElG 237 +++++ +lP gv+n+vtg+ + + ++l+eh+dv+++ GS e + + ++a n+kr+ ++ G FUN_001360-T1 80 VQIFDTSDLPGGVVNIVTGDRDHLTKYLTEHQDVQAMWYFGSAEGSKFVEWSSAVNVKRTFVNYG 144 68999*************************************99999999889999999987766 PP >> DUF3192 Protein of unknown function (DUF3192) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 2.5e-05 0.21 8 76 .. 5 79 .. 1 85 [. 0.73 2 ? -1.4 0.0 0.41 3.5e+03 44 65 .. 97 118 .. 91 124 .. 0.76 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 2.5e-05 DUF3192 8 ydeekeeedWedrqaknrkkl.....aklslgls.keevlellGkaDfseakskkdkelqvlfyRtqraksDgkt 76 +d+ e+e+W +r a+nr+++ ++l+l s +e l + ++ea ++ d ++q lfy a++ g t FUN_001360-T1 5 EDKYYEQESWGKRAAHNRAQIvyymaENLELRHSeFSERLCNMTGCSIQEANREVDMTIQRLFYWGAYADKYGGT 79 4566899************9944433455554331344445566688*****************88877776666 PP == domain 2 score: -1.4 bits; conditional E-value: 0.41 DUF3192 44 lGkaDfseakskkdkelqvlfy 65 G D + ++ +++q ++y FUN_001360-T1 97 TGDRDHLTKYLTEHQDVQAMWY 118 5777777778888888998888 PP >> Mucin_bdg Putative mucin or carbohydrate-binding module # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 2e-05 0.17 48 102 .. 3 54 .. 1 66 [. 0.75 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 2e-05 Mucin_bdg 48 kdGneklrkeveGtekqlakvdeisfeeGdvlkifHaEpsnrLitnkdqkkvlds 102 ++ + +++e G + + +i + + l+++H E s+rL ++ + +++ FUN_001360-T1 3 NNEDKYYEQESWGKRAAHNR-AQIVYYMAENLELRHSEFSERL--CNMTGCSIQE 54 45556677778888888888.99********************..5555555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (180 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 624 (0.0244275); expected 510.9 (0.02) Passed bias filter: 504 (0.0197299); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1828.65 // Query: FUN_001361-T1 [L=182] Description: FUN_001361 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-17 63.3 0.0 5.7e-17 62.9 0.0 1.2 1 Lectin_C Lectin C-type domain ------ inclusion threshold ------ 0.015 15.4 0.0 0.018 15.1 0.0 1.2 1 UL45 UL45 protein, carbohydrate-binding C-type lectin-li 0.029 14.8 0.0 0.056 13.8 0.0 1.5 1 Sec31 Protein transport protein SEC31 Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.9 0.0 6.7e-21 5.7e-17 3 106 .. 59 177 .. 57 178 .. 0.88 Alignments for each domain: == domain 1 score: 62.9 bits; conditional E-value: 6.7e-21 Lectin_C 3 ksweeaqelCqkeggkLvsinskeenkflssllk...ksnkkfWigltdeksegtwkwedgskvnteeytnw...epnnngenedCvel....... 85 k+ ++aq++C+ g++Lv+i+s+ en+f+ +l++ s k++Wigl++e +++ w+dgs y+nw e + + +e C ++ FUN_001361-T1 59 KTRSDAQKFCKASGAELVKITSRPENDFVLALARekaPSLKQVWIGLQYESGAKDFYWSDGSFPV---YKNWapgE-PSGNAREPCGHMwtgqtpv 150 67789***************************99988899*************************...****9944.57778899*********** PP Lectin_C 86 ..ekssgkwndesCns....knpfvCe 106 ++sg+wnd +C+ +n vC+ FUN_001361-T1 151 rrIRASGSWNDLPCSInptfPNGLVCK 177 9999**********8622234556666 PP >> UL45 UL45 protein, carbohydrate-binding C-type lectin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.0 2.2e-06 0.018 74 139 .. 38 104 .. 8 123 .. 0.78 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 2.2e-06 UL45 74 apCpaewiglgdsCirpigknakteeeavatCaayssklisrsa..aklLlevldvfastsaeyseek 139 +C+++w+ + C+ + ++kt ++a + C+a ++l++ + + ++ +l++ + s + ++ + FUN_001361-T1 38 NQCDQGWVLYNSFCYLASA-SVKTRSDAQKFCKASGAELVKITSrpENDFVLALAREKAPSLKQVWIG 104 68*************8765.556*************99986543114555555555555555555555 PP >> Sec31 Protein transport protein SEC31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 6.6e-06 0.056 10 33 .. 143 166 .. 136 168 .. 0.85 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 6.6e-06 Sec31 10 vaSGQtPhLnkkAndGWNDLPlkv 33 + GQtP A WNDLP + FUN_001361-T1 143 MWTGQTPVRRIRASGSWNDLPCSI 166 378******************875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 495 (0.0193776); expected 510.9 (0.02) Passed bias filter: 457 (0.01789); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.37s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1874.50 // Query: FUN_001362-T1 [L=169] Description: FUN_001362 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-21 76.0 0.7 6.4e-21 75.6 0.7 1.2 1 Lectin_C Lectin C-type domain ------ inclusion threshold ------ 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 UL45 UL45 protein, carbohydrate-binding C-type lectin-li Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.6 0.7 5e-25 6.4e-21 3 103 .. 46 157 .. 44 165 .. 0.92 Alignments for each domain: == domain 1 score: 75.6 bits; conditional E-value: 5e-25 Lectin_C 3 ksweeaqelCqkeggkLvsinskeenkflssllk...ksnkkfWigltdeksegtwkwedgskvnteeytnw..epnnngenedCvel........ 85 k+ +eaq++C + g++Lv+i+s++en+f+ +l++ s k++Wigl+++ s + w+d+s ++ ytnw ++ + ++ne+C ++ FUN_001362-T1 46 KTRNEAQQFCVQRGAELVKITSQAENDFVLALARekaPSVKQVWIGLRYQRSVRAFYWSDNSVLT---YTNWapHEPSGNGNEQCGHMwtgrttrf 138 6779****************************99998999*************************...****997779999*************** PP Lectin_C 86 .ekssgkwndesCnsknpf 103 +++sg+wn+ sC +k+ f FUN_001362-T1 139 pARASGYWNNISCATKKVF 157 **************98654 PP >> UL45 UL45 protein, carbohydrate-binding C-type lectin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 1.8e-05 0.23 64 139 .. 13 91 .. 3 117 .. 0.69 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 1.8e-05 UL45 64 ltvplsale..sapCpaewiglgdsCirpigknakteeeavatCaayssklis..rsaaklLlevldvfastsaeyseek 139 l+ + +l+ ++ +++w+ + C+ + ++kt +ea + C ++ ++l++ + a + ++ +l++ + s + ++ + FUN_001362-T1 13 LVSSGGSLKhyMGLNGKGWVPYNSYCYMASD-SIKTRNEAQQFCVQRGAELVKitSQAENDFVLALAREKAPSVKQVWIG 91 55555566533577789*********98765.566**************9975214455677777777777777777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (169 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 482 (0.0188687); expected 510.9 (0.02) Passed bias filter: 418 (0.0163633); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1727.21 // Query: FUN_001363-T1 [L=508] Description: FUN_001363 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-17 64.2 2.0 4e-17 63.4 2.0 1.4 1 Lectin_C Lectin C-type domain 4e-08 34.1 0.0 0.018 16.0 0.0 2.5 2 Ig_3 Immunoglobulin domain 4.1e-06 27.3 0.0 0.016 15.7 0.0 2.4 2 I-set Immunoglobulin I-set domain ------ inclusion threshold ------ 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 TMEM171 Transmembrane protein family 171 0.17 12.7 0.1 2 9.3 0.1 2.3 2 ig Immunoglobulin domain 0.31 11.5 0.0 0.7 10.4 0.0 1.5 1 Ribonuc_L-PSP Endoribonuclease L-PSP Domain annotation for each model (and alignments): >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.4 2.0 9.3e-21 4e-17 2 106 .. 43 147 .. 42 148 .. 0.92 Alignments for each domain: == domain 1 score: 63.4 bits; conditional E-value: 9.3e-21 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllkksnkkfWigltdeksegtwkwedgskvnteeytnw...epnnng.enedCvel....ekss 89 +k w+ a+++C+ g++L+++n+ ++ fl+s + + Wigl ++++w w+dgs+++ +ytnw ep++ + +dC ++ + s FUN_001363-T1 43 EKDWNAAKSACEALGSSLAVVNTDSKQTFLTSEV---TYASWIGL---HKDSNWLWVDGSDLT--NYTNWksgEPKEAAsAYGDCGQMypkgSDSP 130 578******************************7...8999****...99*************..6*****996665550568************* PP Lectin_C 90 gkwndesCnsknpfvCe 106 gkw +e+C+ + ++Ce FUN_001363-T1 131 GKWFSEPCTLVAHYICE 147 ****************8 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 4.2e-06 0.018 12 76 .. 161 225 .. 153 226 .. 0.82 2 ! 15.4 0.0 6.6e-06 0.028 28 74 .. 268 318 .. 248 321 .. 0.76 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 4.2e-06 Ig_3 12 v.veegesvtLtCeaegnppp.titWykngkelssgstskrsssssnstLtisnvtredsGtYtCvA 76 + + g+sv+L+ e+ ++ + ti+W+++ l+++++ ++++++Lti n+ + + G Y+ ++ FUN_001363-T1 161 AsACLGDSVSLQIEIVASYGNlTIQWRHGADLLDDSEHF--ALNEDKTVLTIYNALPPHGGFYQAIV 225 33789**********8888888******99975554444..79********************9665 PP == domain 2 score: 15.4 bits; conditional E-value: 6.6e-06 Ig_3 28 nppptitWykngkelssgstskr....sssssnstLtisnvtredsGtYtC 74 + + +W ++g ++++++ +++s+++tL+is+v +++G Y+ FUN_001363-T1 268 SESGVLWWIHQGAIVRGQDEHYSfpdtEQGSTGTTLQISKVDSQHAGIYEI 318 4444789******73333333336899999999****************85 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 3.8e-06 0.016 10 78 .. 161 228 .. 153 240 .. 0.84 2 ! 9.1 0.0 0.00044 1.9 9 74 .. 252 319 .. 245 334 .. 0.74 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 3.8e-06 I-set 10 vevkeGesaeleckvsGe.pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatns 78 +++ G+s++l++++ ++ +++++W ++ l s+++ +++++ + LtI n+ + G Y+ ++ FUN_001363-T1 161 ASACLGDSVSLQIEIVASyGNLTIQWRHGADLLDDSEHFALNEDK--TVLTIYNALPPHGGFYQAIVSDL 228 566689********988769****************999999888..**********9999999888765 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00044 I-set 9 dvevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaee...gtatLtIsnvkkeDeGkYtck 74 +v+++ G++ l+++ s + W ++g ++ ++++++ +e +tL Is+v+++ +G+Y++ FUN_001363-T1 252 PVTINGGDTGLLKVEKSES--GVLWWIHQGAIVRGqDEHYSFPDTEqgsTGTTLQISKVDSQHAGIYEIL 319 5666666666665544443..4567888888888657888887777667789***************986 PP >> TMEM171 Transmembrane protein family 171 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 5.6e-05 0.24 163 263 .. 377 471 .. 370 479 .. 0.83 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 5.6e-05 TMEM171 163 qilGplivlvGLCffvvahvkkrnnlsvsqdaseseegqtqstepvqvtvgdaviifPPPPPpyfaessasavtqspgassllpsenPPsyysifn 258 i+Gpli l L fvv ++k+ + s ++++ + e ++ ++ pv d +fPP y + s + + sp++ss ++s +y i FUN_001363-T1 377 AIMGPLILL--LVIFVV-CLKR-YSRSRKRNTLKLAE-KKDKQPPVSHLLYDKP-LFPPNAQMYRPPSEPIYADMSPVSSSHPHSSTFGPYGGINV 466 69*****99..567887.6775.66777888888777.4556678888888875.7***********99999*********99999*********9 PP TMEM171 259 dgrtq 263 +grt FUN_001363-T1 467 YGRTM 471 99986 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.29 1.2e+03 19 72 .. 177 227 .. 164 231 .. 0.71 2 ? 9.3 0.1 0.00047 2 27 66 .. 273 316 .. 265 317 .. 0.78 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.29 ig 19 egspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnn 72 + + +++W+++ + +++s++ ++ + l+i n+ + ++G+Y v++ FUN_001363-T1 177 ASYGNLTIQWRHGADLLDDSEH---FALNEDKTVLTIYNALPPHGGFYQAIVSD 227 5566677777777777777777...55566677899999999999999988875 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00047 ig 27 tWskegktkieslk....vkedngrttqssllisnvteedaGtY 66 W+ ++ + ++++ ++++++t+++l+is+v ++aG Y FUN_001363-T1 273 LWWIHQGAIVRGQDehysFPDTEQGSTGTTLQISKVDSQHAGIY 316 5555555555555557777789999*****************99 PP >> Ribonuc_L-PSP Endoribonuclease L-PSP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00017 0.7 54 78 .. 318 342 .. 300 352 .. 0.87 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00017 Ribonuc_L-PSP 54 avLaaagaslsdvvkvtvfladied 78 +L++ag+++ +v++v +f+ d + FUN_001363-T1 318 ILLKEAGCEIRNVIDVHIFVGDSKG 342 579*******************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (508 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 768 (0.0300646); expected 510.9 (0.02) Passed bias filter: 697 (0.0272852); expected 510.9 (0.02) Passed Vit filter: 87 (0.00340575); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4881.42 // Query: FUN_001364-T1 [L=391] Description: FUN_001364 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-49 165.3 0.1 6.8e-49 164.7 0.1 1.3 1 BTB_3 BTB/POZ domain 7.7e-05 23.5 0.0 0.00014 22.7 0.0 1.4 1 BTB_2 BTB/POZ domain ------ inclusion threshold ------ 0.24 11.3 0.3 0.44 10.4 0.3 1.5 1 AvrRpt-cleavage Cleavage site for pathogenic type III effect 0.26 11.6 0.0 0.4 11.0 0.0 1.4 1 AAA_31 AAA domain Domain annotation for each model (and alignments): >> BTB_3 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 164.7 0.1 1.1e-52 6.8e-49 1 106 [] 99 202 .. 99 202 .. 0.98 Alignments for each domain: == domain 1 score: 164.7 bits; conditional E-value: 1.1e-52 BTB_3 1 kltlvvdetrfvvdkslftahPdtmlgrmfssslernltkpnekGeyevaegissevfraildyyktGvikcPpsvsikelreacdyllipfdakt 96 k+tlvvd+trf+v++slf ahP+tmlgrmf+s++e +t++n+kGeyeva+gis++vf++ildyyktG i+cPps+ i+elreacdyllipf+a+ FUN_001364-T1 99 KITLVVDDTRFIVERSLFIAHPNTMLGRMFGSTME--YTTRNDKGEYEVARGISANVFKCILDYYKTGLINCPPSIQIPELREACDYLLIPFNAEV 192 69******************************999..7889******************************************************* PP BTB_3 97 ikcqnlskll 106 i+cqnl++ll FUN_001364-T1 193 IRCQNLRDLL 202 *******997 PP >> BTB_2 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 2.1e-08 0.00014 5 86 .. 104 186 .. 100 193 .. 0.85 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 2.1e-08 BTB_2 5 VgGtrfetskstLtrkpdtlLkklleteeldaydeetneyffDR..spklFetiLnflrtggkLhepeevelkelleElefygl 86 V trf +++s p+t+L++++ +++ +++++++ey + R s ++F++iL++++t g +++p +++ el+e ++ + FUN_001364-T1 104 VDDTRFIVERSLFIAHPNTMLGRMFGSTMEYTTRNDKGEYEVARgiSANVFKCILDYYKT-GLINCPPSIQIPELREACDYLLI 186 6668899999999999**********885566778899******666789**********.88999999*****9999999766 PP >> AvrRpt-cleavage Cleavage site for pathogenic type III effector avirulence factor Avr # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.3 6.9e-05 0.44 11 26 .. 249 265 .. 249 265 .. 0.96 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 6.9e-05 AvrRpt-cleavage 11 eWDendp.asaegYTvi 26 +WDe p + +e YT+i FUN_001364-T1 249 DWDEEYPpSMGEEYTHI 265 8***************8 PP >> AAA_31 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 6.2e-05 0.4 107 164 .. 150 205 .. 74 214 .. 0.87 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 6.2e-05 AAA_31 107 lkeklekvkdeYDyiiiDcpPslglltinaLtaadsvlipiqleayaleGlsqllkti 164 ++++ + d Y +i cpPs+++ a d++lip ++e + l +ll+ + FUN_001364-T1 150 SANVFKCILDYYKTGLINCPPSIQIPELR--EACDYLLIPFNAEVIRCQNLRDLLHEL 205 46788899999***********9987665..589****************99999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (391 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 664 (0.0259933); expected 510.9 (0.02) Passed bias filter: 609 (0.0238403); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3894.36 // Query: FUN_001365-T1 [L=258] Description: FUN_001365 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-27 93.6 3.5 1.5e-26 92.8 3.5 1.4 1 DnaJ DnaJ domain ------ inclusion threshold ------ 0.082 13.7 0.2 0.18 12.7 0.2 1.5 1 FF_RHG35_4th Rho GTPase-activating protein 35-like, FF domai Domain annotation for each model (and alignments): >> DnaJ DnaJ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.8 3.5 1.1e-30 1.5e-26 1 63 [] 3 66 .. 3 66 .. 0.99 Alignments for each domain: == domain 1 score: 92.8 bits; conditional E-value: 1.1e-30 DnaJ 1 dyYeiLgvskdaseeeIkkaYrklalkyHPDknpkdp.eaeekFkeineAyevLsdpekRaaYD 63 dyYeiL+v++ a++++I+k Yrk+alk+HPDknp+++ +aee+Fk ++eAyevLs+++kR +YD FUN_001365-T1 3 DYYEILEVPRAATQDDIRKGYRKQALKWHPDKNPDNKeQAEERFKLVSEAYEVLSNKDKRDIYD 66 8**********************************999*************************9 PP >> FF_RHG35_4th Rho GTPase-activating protein 35-like, FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.2 1.4e-05 0.18 32 52 .. 50 70 .. 43 71 .. 0.86 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.4e-05 FF_RHG35_4th 32 eeayesLsesdrleiYsrHQk 52 eaye Ls++d+++iY+r k FUN_001365-T1 50 SEAYEVLSNKDKRDIYDRYGK 70 79***************9765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (258 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 964 (0.0377373); expected 510.9 (0.02) Passed bias filter: 625 (0.0244666); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2567.61 // Query: FUN_001366-T1 [L=309] Description: FUN_001366 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-24 86.8 0.1 3.3e-24 86.3 0.1 1.3 1 DIOX_N non-haem dioxygenase in morphine synthesis N-te 1.3e-20 74.1 0.0 2.4e-20 73.2 0.0 1.5 1 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily ------ inclusion threshold ------ 0.22 11.1 0.0 0.3 10.6 0.0 1.1 1 hDGE_amylase Glycogen debranching enzyme, glucanotransferase Domain annotation for each model (and alignments): >> DIOX_N non-haem dioxygenase in morphine synthesis N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 86.3 0.1 3.9e-28 3.3e-24 1 115 [. 8 129 .. 8 135 .. 0.88 Alignments for each domain: == domain 1 score: 86.3 bits; conditional E-value: 3.9e-28 DIOX_N 1 iPvidlsrl..........ssedreevlaklreAcrewGffqvvnhgvpeelidelleaakefFalPleeKeklaksp..sfrGygrlgkektdg. 83 iPv+d+s++ s+++ ++++++++eA++++Gf++++nhg+++e ++++++++ +fF l+++ K+k++k++ G+++l +e td+ FUN_001366-T1 8 IPVVDFSAMsveheaiplpSDDRVQTIVRQIHEAFSTVGFVYLKNHGITQERVEKTFAVMDKFFTLSKDLKNKYRKKGelDANGWEALEREITDPt 103 8******989999999987778899*************************************************88876899************** PP DIOX_N 84 kkldwkeffdlgtelpeddpagkplrgpnqwp 115 k +d+ke+fd+g ++ ++r+p + p FUN_001366-T1 104 KPGDLKESFDIGAFDNK------KFRWPTEVP 129 *************9332......344444444 PP >> 2OG-FeII_Oxy 2OG-Fe(II) oxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.2 0.0 2.8e-24 2.4e-20 3 101 .] 178 285 .. 176 285 .. 0.90 Alignments for each domain: == domain 1 score: 73.2 bits; conditional E-value: 2.8e-24 2OG-FeII_Oxy 3 sllvlnyypphpdpel....tlglgphtdasiltillqddvgglqvlkdgk.widvpplpgalvvniGdallllsngryksvlHrvlpvnkgee.. 91 +ll+ nyyp d + ++++g+htd++ +t+l+qdd ggl+v +++k +++ plpg+++vni d ++ ++ +++ s+ Hrv +n++ + FUN_001366-T1 178 ALLRFNYYPRITDIGQikpgQIRCGEHTDYGGITLLFQDDAGGLEVVNRDKkFVSATPLPGTIIVNIADLMQRWTADKFVSTVHRVIIPNGELKqk 273 67999**9999777777777999***********************988777***********************************666644367 PP 2OG-FeII_Oxy 92 ..Risiafflrp 101 R siaff+ p FUN_001366-T1 274 tpRRSIAFFYDP 285 88*******987 PP >> hDGE_amylase Glycogen debranching enzyme, glucanotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 3.6e-05 0.3 286 349 .. 29 92 .. 20 104 .. 0.81 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 3.6e-05 hDGE_amylase 286 edvkaileql...lnrikYlrldehGPklgeitkkeplvetYFtrlekeestkkkdgkklalannGW 349 + v++i+ q+ ++++ ++ l++hG ++++ k+ +++ ++Ft ++ k+k kk l nGW FUN_001366-T1 29 DRVQTIVRQIheaFSTVGFVYLKNHGITQERVEKTFAVMDKFFTLS---KDLKNKYRKKGELDANGW 92 555566555511167899**************************99...567777778999****** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 616 (0.0241143); expected 510.9 (0.02) Passed bias filter: 600 (0.023488); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.35s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 3050.19 // Query: FUN_001367-T1 [L=539] Description: FUN_001367 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-32 113.3 0.7 2.3e-31 109.3 0.6 2.2 2 Beta-prop_THOC3 THOC3 beta-propeller domain 3.2e-27 96.1 0.7 5.1e-17 62.6 0.6 3.1 3 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 2.6e-23 83.2 0.5 2e-12 47.6 0.3 3.1 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1.5e-22 80.7 0.4 1.5e-13 51.2 0.2 3.0 3 Beta-prop_WDR5 WDR5 beta-propeller domain 4.6e-20 72.3 2.2 4e-19 69.2 0.3 2.3 2 WD40_Prp19 Prp19 WD40 domain 1.4e-19 70.1 7.6 2.5e-05 25.1 0.1 5.7 6 WD40 WD domain, G-beta repeat 2.2e-19 70.1 0.4 2.3e-16 60.2 0.8 2.2 2 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 3.6e-14 53.3 0.1 4.9e-05 23.4 0.0 3.3 3 Beta-prop_RIG_2nd RIG second beta-propeller 7.8e-14 51.9 0.0 1.1e-11 44.8 0.0 3.2 3 WDR55 WDR55 2.1e-13 50.6 0.6 1e-05 25.4 0.0 3.4 3 WD40_WDHD1_1st WDHD1 first WD40 domain 3.6e-13 50.0 0.0 1.2e-05 25.3 0.0 2.8 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 8.3e-13 48.8 0.1 2.5e-05 24.3 0.1 3.8 4 Beta-prop_EML_2 Echinoderm microtubule-associated 4.2e-12 46.3 0.0 1.1e-05 25.3 0.0 2.7 2 EIF3I EIF3I 6.8e-12 45.8 0.1 1.6e-06 28.1 0.0 3.1 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 9.1e-11 42.2 0.1 4.5e-07 30.1 0.1 2.4 2 Beta-prop_EIPR1 EIPR1 beta-propeller 1e-10 41.8 0.1 1.4e-05 25.0 0.0 3.2 4 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 1.3e-10 41.6 0.2 3.7e-08 33.5 0.1 3.1 4 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 4.8e-08 33.4 0.3 0.0034 17.8 0.0 3.5 3 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 1.2e-07 31.7 3.0 0.00069 19.3 0.4 2.4 2 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 2.1e-07 31.0 1.6 0.001 19.0 0.0 3.2 3 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 3.2e-07 31.0 0.3 0.0019 18.9 0.1 3.5 2 ANAPC4_WD40 Anaphase-promoting complex subunit 1.6e-06 27.9 0.0 1.9e-05 24.3 0.1 2.4 2 WD40_Gbeta G protein beta WD-40 repeat protei 2e-06 27.3 0.0 0.00027 20.3 0.0 2.1 2 Beta-prop_WDR41 WDR41 2.3e-06 27.4 2.8 4.6e-06 26.5 0.8 2.0 2 Beta-prop_Aladin Aladin seven-bladed propeller 3.8e-06 27.1 0.5 3.7e-05 23.9 0.4 2.8 2 Beta-prop_EML Echinoderm microtubule-associated 2.4e-05 24.0 0.0 0.3 10.5 0.1 3.0 3 WD_LRWD1 Leucine-rich repeat and WD repeat- 3e-05 23.9 0.2 0.043 13.5 0.0 2.6 2 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 5.2e-05 22.5 12.1 0.034 13.2 0.0 3.7 3 Beta-prop_RIG_1st RIG first beta-propeller 5.5e-05 22.7 0.1 0.13 11.6 0.0 3.0 3 NBCH_WD40 Neurobeachin beta propeller domain 0.00016 21.3 0.5 0.45 9.9 0.1 2.3 2 MIOS_WD40 MIOS, WD40 repeat 0.0004 20.3 0.0 0.00065 19.7 0.0 1.3 1 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 0.00063 19.0 1.4 0.066 12.4 0.3 2.9 3 Beta-prop_IFT140_1st IFT140 first beta-propeller 0.00077 19.1 0.0 0.12 11.9 0.1 2.2 2 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.001 18.6 0.0 0.31 10.4 0.0 2.5 2 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 0.0025 17.5 0.1 0.0041 16.8 0.1 1.4 1 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 0.0063 16.0 0.6 0.83 9.0 0.2 2.8 3 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 0.0081 15.5 1.9 0.8 8.9 0.0 3.6 4 Beta-prop_SCAP SCAP Beta-propeller ------ inclusion threshold ------ 0.073 12.5 0.0 1.9 7.9 0.0 2.6 3 Beta-prop_LRRK2 LRRK2 beta propeller 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 WDR54 WDR54 Domain annotation for each model (and alignments): >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.9 0.0 0.0059 3.9 182 205 .. 198 221 .. 132 233 .. 0.67 2 ! 109.3 0.6 3.6e-34 2.3e-31 12 202 .. 197 409 .. 194 420 .. 0.86 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0059 Beta-prop_THOC3 182 kgrylAvGsaDalvslWDleelic 205 g+++AvGs + +WDl+ + FUN_001367-T1 198 PGNFVAVGSMEPHIDIWDLDLVDT 221 245566666666666666554444 PP == domain 2 score: 109.3 bits; conditional E-value: 3.6e-34 Beta-prop_THOC3 12 adGkrLasgsaDktvrvwnle...............ksklsk..etelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktk 88 G+ +a gs + +w+l+ k+k++k +++ +gh+d+V l+w+p +++la++s+D +v lWd+ + k+++ ++++ FUN_001367-T1 197 TPGNFVAVGSMEPHIDIWDLDlvdtlqpvvslgkkkKKKSKKklQNSEEGHSDAVLDLSWNPLVRNVLASGSADCSVILWDLSQPKPVHLLRHH 290 56899999***********996666666655554321222221233458********************************************9 PP Beta-prop_THOC3 89 genin.lawsp.dGktiavgskddtvslidvrtgkv.kkeekfkkevnevafspdgk.llllttgdgtvevlsypsleevktlkahtsnclcva 178 ++ ++ l+w+p + + i++gs d+ +++d+r+ + +k++kf++ev+ v +++ + +l++t++g+v + ++ + ++v tlkah +++ +a FUN_001367-T1 291 KDKVQsLQWHPyESQSILTGSFDKRAKVVDCRNPESnIKSWKFNSEVERVLWNHFSPfNFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLA 384 999855*****889*******************7653899**************876268999******************************* PP Beta-prop_THOC3 179 fdpkg.rylAvGsaDalvslWDlee 202 ++ + l+++saD++v++WD+++ FUN_001367-T1 385 LSSQVpGCLVTASADETVKVWDIQD 409 *9887369**************997 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.17 1.1e+02 62 82 .. 193 218 .. 156 233 .. 0.60 2 ! 62.6 0.6 7.7e-20 5.1e-17 124 233 .. 237 346 .. 230 355 .. 0.87 3 ! 28.2 0.0 2.4e-09 1.6e-06 106 173 .. 350 416 .. 344 456 .. 0.85 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.17 WD40_CDC20-Fz 62 d.....gelLavGtssgevelwdvek 82 + g+++avG+ + ++ +wd FUN_001367-T1 193 EdsstpGNFVAVGSMEPHIDIWDLDL 218 33444477788888888888887654 PP == domain 2 score: 62.6 bits; conditional E-value: 7.7e-20 WD40_CDC20-Fz 124 elevvktlkahkqevcglkwspd.grllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntnt.gkllks 217 + + +++ ++h++ v l+w+p +++lAsG+ d +v +wdl++ +p++ l++hk +v+ l+W+p++++ + tG+ Dk+ ++ ++++ ++ +ks FUN_001367-T1 237 KKKLQNSEEGHSDAVLDLSWNPLvRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYESQSILTGS--FDKRAKVVDCRNpESNIKS 330 445567789*************63799**********************************************97..5*********763789*** PP WD40_CDC20-Fz 218 vdtgsqvtsllwskee 233 ++ +s+v +lw++ + FUN_001367-T1 331 WKFNSEVERVLWNHFS 346 ************9854 PP == domain 3 score: 28.2 bits; conditional E-value: 2.4e-09 WD40_CDC20-Fz 106 lssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdg.rllAsGgndntvkiwdlrslspllkl 173 +++ +++g++++ Dvrt + v tlkah + + gl++s++ l + + d+tvk+wd+++++p l FUN_001367-T1 350 FLVSTENGHVFCCDVRTDD--PVYTLKAHDDAIPGLALSSQVpGCLVTASADETVKVWDIQDNKPSLVT 416 6788999***********8..4689*************9985389*****************9997654 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.12 77 40 100 .. 198 216 .. 135 222 .. 0.58 2 ! 47.6 0.3 3.1e-15 2e-12 39 147 .. 197 326 .. 193 344 .. 0.82 3 ! 31.7 0.0 2.4e-10 1.5e-07 84 145 .. 349 410 .. 323 422 .. 0.80 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.12 Beta-prop_WDR3_1st 40 dgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDv 100 g+ +a Gs + +i +wD+ FUN_001367-T1 198 P------------------------------------------GNFVAVGSMEPHIDIWDL 216 2..........................................334555555555555553 PP == domain 2 score: 47.6 bits; conditional E-value: 3.1e-15 Beta-prop_WDR3_1st 39 pdgkklavGyadgsirlwdl...................esgelevtfngHksavtalafdkd.gsrLasGskDtdiivwDvvaeaglfrL 109 + g+ +avG+++ +i +wdl ++++l+ + +gH+ av l++++ + LasGs+D+++i+wD+ + + ++ L FUN_001367-T1 197 TPGNFVAVGSMEPHIDIWDLdlvdtlqpvvslgkkkkkkSKKKLQNSEEGHSDAVLDLSWNPLvRNVLASGSADCSVILWDLSQPKPVHLL 287 5578899999999999999977777777777777655444445578889************9725679*********************** PP Beta-prop_WDR3_1st 110 kgHkdqvtsvafle.ekkvlvssSkDtliklWdletqhc 147 + Hkd+v+s+++ + e++ ++++S D+ k+ d ++ + FUN_001367-T1 288 RHHKDKVQSLQWHPyESQSILTGSFDKRAKVVDCRNPES 326 *************7356899**********999877655 PP == domain 3 score: 31.7 bits; conditional E-value: 2.4e-10 Beta-prop_WDR3_1st 84 srLasGskDtdiivwDvvaeaglfrLkgHkdqvtsvaflee.kkvlvssSkDtliklWdletq 145 + L+s ++ ++ Dv ++ +++Lk H d++ +a++++ +lv++S D+++k+Wd++ + FUN_001367-T1 349 NFLVS-TENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQvPGCLVTASADETVKVWDIQDN 410 34555.678899**************************987368****************976 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.041 27 229 251 .. 196 218 .. 125 235 .. 0.58 2 ! 51.2 0.2 2.3e-16 1.5e-13 60 164 .. 199 324 .. 196 349 .. 0.67 3 ! 23.9 0.0 4.6e-08 3e-05 103 166 .. 349 412 .. 333 467 .. 0.75 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.041 Beta-prop_WDR5 229 etggklvvsGsedgkvyiwdlqs 251 +t g++v+ Gs + ++ iwdl FUN_001367-T1 196 STPGNFVAVGSMEPHIDIWDLDL 218 44445666666666666666544 PP == domain 2 score: 51.2 bits; conditional E-value: 2.3e-16 Beta-prop_WDR5 60 skllasaSDDktvriwdve...................tgkllktlkgHtnyvfcvaFnpk.gnllvSGsfDetvrlWdvrtgkclktlpaHsdp 134 ++++a +S + iwd++ ++kl + +gH++ v+ +++np n+l+SGs+D +v lWd+++ k ++ l H+d+ FUN_001367-T1 199 GNFVAVGSMEPHIDIWDLDlvdtlqpvvslgkkkkkksKKKLQNSEEGHSDAVLDLSWNPLvRNVLASGSADCSVILWDLSQPKPVHLLRHHKDK 293 45666666666777777777777777777776665554444555667888888888888753678888888888888888888888888888888 PP Beta-prop_WDR5 135 vsavdfnr.dgtlivsssyDgliriwdtetg 164 v++++++ +++ i+++s+D ++ d+++ FUN_001367-T1 294 VQSLQWHPyESQSILTGSFDKRAKVVDCRNP 324 8888877425667888888888888777654 PP == domain 3 score: 23.9 bits; conditional E-value: 4.6e-08 Beta-prop_WDR5 103 nllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgt.livsssyDgliriwdtetgqc 166 n+lvS+ + v dvrt + tl+aH d++ +++++++ ++v++s D ++++wd++ + FUN_001367-T1 349 NFLVST-ENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVPgCLVTASADETVKVWDIQDNKP 412 666665.4677889999999999999999999999999887644899999999999999987664 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.16 1e+02 147 165 .. 199 217 .. 138 234 .. 0.78 2 ! 69.2 0.3 6.1e-22 4e-19 36 209 .. 235 410 .. 225 419 .. 0.88 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.16 WD40_Prp19 147 GlllgtGtkdgtvkiWDik 165 G+++++G+ + + iWD+ FUN_001367-T1 199 GNFVAVGSMEPHIDIWDLD 217 8999999999999999986 PP == domain 2 score: 69.2 bits; conditional E-value: 6.1e-22 WD40_Prp19 36 resekvlatlkghtkkvtavafhp.sedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptg.dylvsaskDgtwalhdlet.gktllk 128 ++++k ++ +gh+ +v ++ ++p ++vl s+saD +v +w+ ++ + +++l++hk++v+sl+ hp + + ++++s D+ ++ d ++ ++++++ FUN_001367-T1 235 KSKKKLQNSEEGHSDAVLDLSWNPlVRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYEsQSILTGSFDKRAKVVDCRNpESNIKS 330 45667777778************9667899*************************************9725689*************984668888 PP WD40_Prp19 129 vkdeeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeN.GYyLAsasedgtvklWDLRkl 209 k +++ e++ +f P l + t++g v D+++ + v +l++h +a+ la+S L++as+d+tvk+WD+ FUN_001367-T1 331 WKFNSEVERVLWNHFSPFNFL--VSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQvPGCLVTASADETVKVWDIQDN 410 888888888988999996655..6899******************************99854589*************9765 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 7.8 5.1e+03 21 33 .. 141 153 .. 138 157 .. 0.77 2 ? 2.2 0.0 0.67 4.4e+02 20 39 .] 196 215 .. 189 215 .. 0.90 3 ! 25.1 0.1 3.8e-08 2.5e-05 4 39 .] 241 277 .. 238 277 .. 0.87 4 ! 19.6 0.0 2.1e-06 0.0014 2 39 .] 282 320 .. 281 320 .. 0.92 5 ? -0.5 0.1 5 3.3e+03 4 20 .. 352 365 .. 348 369 .. 0.72 6 ! 22.1 0.0 3.5e-07 0.00023 3 39 .] 369 406 .. 367 406 .. 0.90 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 7.8 WD40 21 pdgsllasgsdDg 33 p+++l+++g D FUN_001367-T1 141 PNDNLIVAGHVDQ 153 999****996664 PP == domain 2 score: 2.2 bits; conditional E-value: 0.67 WD40 20 spdgsllasgsdDgtvklWd 39 s g+++a+gs+ ++ +Wd FUN_001367-T1 196 STPGNFVAVGSMEPHIDIWD 215 66799**************9 PP == domain 3 score: 25.1 bits; conditional E-value: 3.8e-08 WD40 4 lrtlkgHtsgVtslafspdgsl.lasgsdDgtvklWd 39 + + +gH+++V +l+++p + lasgs+D++v lWd FUN_001367-T1 241 QNSEEGHSDAVLDLSWNPLVRNvLASGSADCSVILWD 277 55668**999************5679**********9 PP == domain 4 score: 19.6 bits; conditional E-value: 2.1e-06 WD40 2 kllrtlkgHtsgVtslafspdgsl.lasgsdDgtvklWd 39 k+++ l+ H++ V sl ++p s +++gs D++ k+ d FUN_001367-T1 282 KPVHLLRHHKDKVQSLQWHPYESQsILTGSFDKRAKVVD 320 78999****999************999********9965 PP == domain 5 score: -0.5 bits; conditional E-value: 5 WD40 4 lrtlkgHtsgVtslafs 20 + t +gH V +++ FUN_001367-T1 352 VSTENGH---VFCCDVR 365 5666899...9999765 PP == domain 6 score: 22.1 bits; conditional E-value: 3.5e-07 WD40 3 llrtlkgHtsgVtsla.fspdgsllasgsdDgtvklWd 39 +++tlk+H++++ +la s+ l+++s+D tvk+Wd FUN_001367-T1 369 PVYTLKAHDDAIPGLAlSSQVPGCLVTASADETVKVWD 406 89******999*99998777777799***********9 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.2 0.8 3.5e-19 2.3e-16 79 214 .. 196 334 .. 139 346 .. 0.80 2 ! 7.5 0.0 0.0037 2.4 125 203 .. 372 454 .. 367 489 .. 0.70 Alignments for each domain: == domain 1 score: 60.2 bits; conditional E-value: 3.5e-19 Beta-prop_CAF1B_HIR1 79 spsgelLasgdDesviiiWklkeeeeeinlle.eeeeenketwlvlkvlrGhledvyDlswspd.skklisgsvDntailWdvekgkkl 165 s+ g+++a g+ e +i iW l ++ ++++ +++++k + Gh + v Dlsw p + l sgs D ++ilWd+++ k + FUN_001367-T1 196 STPGNFVAVGSMEPHIDIWDLDLVDTLQPVVSlGKKKKKKSKKKLQNSEEGHSDAVLDLSWNPLvRNVLASGSADCSVILWDLSQPKPV 284 456899**************999887556666456666677777888899************96256789******************* PP Beta-prop_CAF1B_HIR1 166 ailkdhkgfvqgvawdPkn.qyvatlssDrslrifdiktkkvvarvskak 214 ++l++hk+ vq+ w P + q + t s D+ +++d+++ + + k + FUN_001367-T1 285 HLLRHHKDKVQSLQWHPYEsQSILTGSFDKRAKVVDCRNPESNIKSWKFN 334 *****************75389**************99988777766665 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0037 Beta-prop_CAF1B_HIR1 125 vlrGhledvyDlswspds.kklisgsvDntailWdvekgkklailkdhkgf..vqgvawdPknqyvatlssDrs.lrifdikt 203 +l+ h + + l+ s++ +l+++s D t+ +Wd++ k + + + ++ + +P+ +v + +++ lr++di FUN_001367-T1 372 TLKAHDDAIPGLALSSQVpGCLVTASADETVKVWDIQDNKPSLVTSRNPQMgrLLNTQCCPEAPFVFSFGGEKQgLRTIDIMD 454 689999999999998775269****************9988777665433311344555666666666655543356665555 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 7.5e-08 4.9e-05 129 253 .. 143 287 .. 131 290 .. 0.79 2 ! 13.2 0.1 9.2e-05 0.06 211 251 .. 288 328 .. 284 350 .. 0.83 3 ! 14.1 0.0 4.9e-05 0.032 170 251 .. 339 414 .. 327 424 .. 0.75 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 7.5e-08 Beta-prop_RIG_2nd 129 dslLlvgtedGalqllerkkelekayskllkqeallsryitdiawsples.......nklAvvandkvivilef.............keeer 200 d+l++ g d ++le + e++ s+++++ ll+ + i w ++ n +Av + + i i ++ k++++ FUN_001367-T1 143 DNLIVAGHVDQDFSVLEISVYNEEEGSQYVHHDILLEAFPLAIEWLDFDPedsstpgNFVAVGSMEPHIDIWDLdlvdtlqpvvslgKKKKK 234 56666666666666777776666666667777777777777777655544444778899999999999999999999999999998877777 PP Beta-prop_RIG_2nd 201 nletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekeelt 253 + +++ ++ + +++++ +++w++ n+l s s+d +v +Wdl++p+ +l+ FUN_001367-T1 235 KSKKKLQNSEEGHSDAVLDLSWNPLVRNVLASGSADCSVILWDLSQPKPVHLL 287 777777888888***********************************988765 PP == domain 2 score: 13.2 bits; conditional E-value: 9.2e-05 Beta-prop_RIG_2nd 211 saekasitsvkwsnansnlllsfsidgkvkvWdleepekee 251 +++k++++s++w +++s+ +l+ s+d ++kv d+++pe++ FUN_001367-T1 288 RHHKDKVQSLQWHPYESQSILTGSFDKRAKVVDCRNPESNI 328 679********************************999754 PP == domain 3 score: 14.1 bits; conditional E-value: 4.9e-05 Beta-prop_RIG_2nd 170 diawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekee 251 + w+ ++ + v++++ ++ ++ + + t +a+ ++i ++ s++ l++ s+d++vkvWd+++++ + FUN_001367-T1 339 RVLWNHFSPFNFLVSTENGHVFCCDVRT------DDPVYTLKAHDDAIPGLALSSQVPGCLVTASADETVKVWDIQDNKPSL 414 5556666666666666666666666653......344578899********************************9887544 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 1 6.6e+02 15 42 .. 139 166 .. 134 178 .. 0.73 2 ? -2.1 0.0 3.4 2.3e+03 273 293 .. 196 216 .. 191 222 .. 0.78 3 ! 44.8 0.0 1.7e-14 1.1e-11 8 173 .. 249 414 .. 247 431 .. 0.83 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 1 WDR55 15 fhPsediiavgtidGdvllykysneene 42 ++P++++i++g++d d + + s ++e FUN_001367-T1 139 IKPNDNLIVAGHVDQDFSVLEISVYNEE 166 68999********999998887765443 PP == domain 2 score: -2.1 bits; conditional E-value: 3.4 WDR55 273 skdgkllassshdqkvkFwni 293 s+ g+++a s++ ++ +w++ FUN_001367-T1 196 STPGNFVAVGSMEPHIDIWDL 216 666788888888888888886 PP == domain 3 score: 44.8 bits; conditional E-value: 1.7e-14 WDR55 8 dlvvdisfhP.sediiavgtidGdvllykysneenenkellslehhkkscraveFse.dGkklfsvskDksiavldvetgkl.kkkiekahespiy 100 d v+d+s P ++++a g+ d +v+l+ s+ k ++ l+hhk++++++++ + +++++ s Dk +v+d+ + + +k ++ e FUN_001367-T1 249 DAVLDLSWNPlVRNVLASGSADCSVILWDLSQP----KPVHLLRHHKDKVQSLQWHPyESQSILTGSFDKRAKVVDCRNPESnIKSWKFNSEVERV 340 78999999995589*****************74....4577899**********98638999***************9866514555555555555 PP WDR55 101 sllvidenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdee.kklLlatsgdGtltvfnirkkklev 173 + + + ++G+v D+R++++v++lk h+d i l+++++ +L+++s d t++v++i+ +k + FUN_001367-T1 341 LWNHFSPFNFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQvPGCLVTASADETVKVWDIQDNKPSL 414 56678888899999*****************************987762579****************998544 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.048 31 130 164 .. 184 223 .. 133 244 .. 0.58 2 ! 19.5 0.1 9.7e-07 0.00063 214 278 .. 240 304 .. 221 313 .. 0.74 3 ! 25.4 0.0 1.6e-08 1e-05 56 173 .. 304 423 .. 302 436 .. 0.84 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.048 WD40_WDHD1_1st 130 pvlsvaldpkg.....eylaSsscDGtvkiWdieskecvk 164 ++ ++++dp++ +++a s++ ++ iWd++ ++++ FUN_001367-T1 184 AIEWLDFDPEDsstpgNFVAVGSMEPHIDIWDLDLVDTLQ 223 5555666665544444566666666666666665544444 PP == domain 2 score: 19.5 bits; conditional E-value: 9.7e-07 WD40_WDHD1_1st 214 fklsknklsedisivafSpcG.kylaaatvdgeilvWdvatkeliervkhekklaitslaWnpken 278 + s++ +s+ + +++ p + la+++ d ++++Wd+++ + + ++h+k ++ sl W+p e+ FUN_001367-T1 240 LQNSEEGHSDAVLDLSWNPLVrNVLASGSADCSVILWDLSQPKPVHLLRHHK-DKVQSLQWHPYES 304 3334555666666677777653678999999999999999999999999886.8899999999865 PP == domain 3 score: 25.4 bits; conditional E-value: 1.6e-08 WD40_WDHD1_1st 56 sdklvvatddntvqlytfpegekdgiltrftapvthialskdgkl.laagseDftikvvsvedsskqktleghkapvlsvaldpkg.eylaSssc 148 s+ +++++ d+ +++++ + e++ +f+++v + ++ + +++e+ ++ +++v++ + + tl+ h++++ +al+++ l+++s FUN_001367-T1 304 SQSILTGSFDKRAKVVDCRNPESNIKSWKFNSEVERVLWNHFSPFnFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVpGCLVTASA 398 567788888888888888888888889999999999999987766256788999*****************************997589****** PP WD40_WDHD1_1st 149 DGtvkiWdieskecvktlkvlpksn 173 D tvk+Wdi++++ + + p++ FUN_001367-T1 399 DETVKVWDIQDNKPSLVTSRNPQMG 423 ***********99876666555555 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.1 3.2e-07 0.00021 192 255 .. 248 311 .. 194 319 .. 0.66 2 ! 25.3 0.0 1.9e-08 1.2e-05 167 256 .. 352 442 .. 331 445 .. 0.92 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 3.2e-07 Beta-prop_WDR36-Utp21_1st 192 egpvtsisFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqp.llvtsg 255 +++v +s ++vla+gs++ +++lwdL++ + vh lr H+ +v++l++ p + ++t + FUN_001367-T1 248 SDAVLDLSWNPLVRNVLASGSADCSVILWDLSQPKPVHLLR-HHKDKVQSLQWHPYESqSILTGS 311 234666666666699*************************7.6999*******987541455555 PP == domain 2 score: 25.3 bits; conditional E-value: 1.9e-08 Beta-prop_WDR36-Utp21_1st 167 iglasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssGdialwdLekr.rlvhvlrnaHeggvtkleflpgqp 249 +++++G+++ ++++d + +lk++++++ ++ + + l+t+s++ ++ +wd++++ + + rn g+ + ++ p+ p FUN_001367-T1 352 VSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVPGCLVTASADETVKVWDIQDNkPSLVTSRNPQMGRLLNTQCCPEAP 435 789*****************************************************99735566677888899*********99 PP Beta-prop_WDR36-Utp21_1st 250 llvtsga 256 ++ + g+ FUN_001367-T1 436 FVFSFGG 442 9999875 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.011 7.1 47 111 .. 139 217 .. 131 237 .. 0.73 2 ! 13.1 0.0 9.5e-05 0.062 225 265 .. 237 277 .. 230 278 .. 0.87 3 ! 24.3 0.1 3.8e-08 2.5e-05 3 113 .. 296 410 .. 294 419 .. 0.86 4 ! 10.7 0.0 0.00053 0.35 3 35 .. 382 415 .. 380 431 .. 0.81 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.011 Beta-prop_EML_2 47 fspdgkllavGlkdGsvlvl.....daetleevve....vkdrkeaisdikfspd.....gklLavgshdnkiylYdvs 111 ++p+++l+++G d ++ vl ++e+++++v+ ++ ai+ + f p+ g+++avgs + +i+++d++ FUN_001367-T1 139 IKPNDNLIVAGHVDQDFSVLeisvyNEEEGSQYVHhdilLEAFPLAIEWLDFDPEdsstpGNFVAVGSMEPHIDIWDLD 217 57888999999988888775333336677777654233346677899999999975666689**************975 PP == domain 2 score: 13.1 bits; conditional E-value: 9.5e-05 Beta-prop_EML_2 225 kkakykkykgHsshVtnvrFladdsylistGGaDasvfqWk 265 kk+ +++ +gHs V ++++ + ++++ G aD+sv+ W FUN_001367-T1 237 KKKLQNSEEGHSDAVLDLSWNPLVRNVLASGSADCSVILWD 277 555567779*******************************7 PP == domain 3 score: 24.3 bits; conditional E-value: 3.8e-08 Beta-prop_EML_2 3 GLathpsep.qfvTagdDktvrlWdlek.kklvakvklekearsvafspdgk.llavGlkdGsvlvldaetleevvevkdrkeaisdikfspdg 93 L hp e+ +++T++ Dk+ + d+++ ++ +++ k+++e++ v +++ + v +++G+v++ d +t + v+++k +++ai ++ s++ FUN_001367-T1 296 SLQWHPYESqSILTGSFDKRAKVVDCRNpESNIKSWKFNSEVERVLWNHFSPfNFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQV 389 6889999862669*************9845678888******9999987555279***********************************9975 PP Beta-prop_EML_2 94 .klLavgshdnkiylYdvskk 113 +L+ +s+d++++++d++++ FUN_001367-T1 390 pGCLVTASADETVKVWDIQDN 410 389999***********9875 PP == domain 4 score: 10.7 bits; conditional E-value: 0.00053 Beta-prop_EML_2 3 GLathpsep.qfvTagdDktvrlWdlekkklvak 35 GLa + p + vTa+ D+tv +Wd++++k FUN_001367-T1 382 GLALSSQVPgCLVTASADETVKVWDIQDNKPSLV 415 8888888874669*************99876554 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 1.6e-08 1.1e-05 127 228 .. 228 333 .. 218 338 .. 0.76 2 ! 19.4 0.0 9.9e-07 0.00065 145 250 .. 333 443 .. 322 465 .. 0.74 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.6e-08 EIF3I 127 irdeeeeeeeepvlkieve.eskvtvalwsaldkt.iitghedgeiskydlktgeklksvkehekqitdlqlsk.dktylitaskDktaklldvet 219 + +++++++++++ + e ++ v w+ l + + +g++d ++ +dl++ + ++ ++h+++++ lq+++ +++ ++t s Dk ak++d+++ FUN_001367-T1 228 LGKKKKKKSKKKLQNSEEGhSDAVLDLSWNPLVRNvLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPyESQSILTGSFDKRAKVVDCRN 323 4455555666666555554146778899*998665056799*******************************982566789************998 PP EIF3I 220 le.vlktykt 228 e +k++k FUN_001367-T1 324 PEsNIKSWKF 333 6524666665 PP == domain 2 score: 19.4 bits; conditional E-value: 9.9e-07 EIF3I 145 eeskvtvalwsaldkt.iitghedgeiskydlktgeklksvkehekqitdlqlskdk.tylitaskDktaklldvet....levlktykterpvns 234 +s+v+ +lw++ + + ++++e+g++ d++t++ + + k+h+++i l ls++ +l+tas D+t k++d+++ l + ++ + r +n+ FUN_001367-T1 333 FNSEVERVLWNHFSPFnFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVpGCLVTASADETVKVWDIQDnkpsLVTSRNPQMGRLLNT 428 4577888888887764278999*****************************998775279**************9862222445556666666776 PP EIF3I 235 aaisplkdfvvlGGGq 250 + +p fv GG+ FUN_001367-T1 429 QC-CPEAPFVFSFGGE 443 65.5667777665655 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.35 2.3e+02 121 141 .. 196 216 .. 190 235 .. 0.90 2 ! 13.8 0.0 5.7e-05 0.037 237 291 .. 245 301 .. 233 304 .. 0.80 3 ! 28.1 0.0 2.4e-09 1.6e-06 156 271 .. 290 409 .. 287 415 .. 0.86 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.35 Beta-prop_WDR36-Utp21_2nd 121 ssCGnfvviGyssGhvdrfNl 141 s+ Gnfv +G+ + h+d + l FUN_001367-T1 196 STPGNFVAVGSMEPHIDIWDL 216 677**************9986 PP == domain 2 score: 13.8 bits; conditional E-value: 5.7e-05 Beta-prop_WDR36-Utp21_2nd 237 sghknritDltfspdarWli.tasmDstirtwdlpsgkliDvfl.vesaatslslsp 291 +gh+ + Dl+++p r ++ + s D+++ wdl++ k + +++ ++ + sl+ p FUN_001367-T1 245 EGHSDAVLDLSWNPLVRNVLaSGSADCSVILWDLSQPKPVHLLRhHKDKVQSLQWHP 301 79*************9976516699***********999999883446677777655 PP == domain 3 score: 28.1 bits; conditional E-value: 2.4e-09 Beta-prop_WDR36-Utp21_2nd 156 hkkavrGvavdal.nqvvitagadkklkfwkfks.kklletlkleasisklvlhressl.lavalddfsilvvDidtrrvvRkf 236 hk++v+ ++ +q ++t++ dk+ k+ + ++ ++ +++ k+++++++++ ++ s + v++++ + D+ t v ++ FUN_001367-T1 290 HKDKVQSLQWHPYeSQSILTGSFDKRAKVVDCRNpESNIKSWKFNSEVERVLWNHFSPFnFLVSTENGHVFCCDVRTDDPVYTL 373 6777777776654157899************998467799**********99888776636799******************** PP Beta-prop_WDR36-Utp21_2nd 237 sghknritDltfspda.rWlitasmDstirtwdlps 271 + h i l++s + l+tas D t+++wd++ FUN_001367-T1 374 KAHDDAIPGLALSSQVpGCLVTASADETVKVWDIQD 409 ************9887368**************986 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 2.3e-06 0.0015 188 277 .. 233 316 .. 195 319 .. 0.91 2 ! 30.1 0.1 6.9e-10 4.5e-07 158 280 .] 291 405 .. 287 405 .. 0.90 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 2.3e-06 Beta-prop_EIPR1 188 RakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstl 277 ++k+kk++ n e h + v ++ ++p+ n l++ d+ v ++D+ ++++ l+ h+ v++ ++ p + il++s d+ FUN_001367-T1 233 KKKSKKKLQNSEEGH-SDAVLDLSWNPLVRNVLASGSADCSVILWDLS-----QPKPVHLLRHHKDKVQSLQWHPYESQSILTGSFDKRA 316 467788999999999.88999**************************9.....6789999*************************99875 PP == domain 2 score: 30.1 bits; conditional E-value: 6.9e-10 Beta-prop_EIPR1 158 geelrvaAldphdsslvlvace.sglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelka 250 +++++ + p++s+ +l + + +++D R+ + s n++ + + v+ v +++ + ++l + ++g v D+R t ++ +lka FUN_001367-T1 291 KDKVQSLQWHPYESQSILTGSFdKRAKVVDCRNPE--S--NIKSWKFNSEVERVLWNHFSPFNFLVSTENGHVFCCDVR-----TDDPVYTLKA 375 46788889*******999866449*******9754..4..6777777789*****************************.....8889999*** PP Beta-prop_EIPR1 251 heHtvkkvlfNpfydeLilscssdstlkLw 280 h+ ++ ++ ++ + ++++s+d+t+k w FUN_001367-T1 376 HDDAIPGLALSSQVPGCLVTASADETVKVW 405 *****************************9 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.77 5.1e+02 182 209 .. 194 221 .. 135 232 .. 0.74 2 ! 9.0 0.0 0.0016 1 215 281 .. 246 314 .. 192 315 .. 0.68 3 ! 12.2 0.0 0.00016 0.11 53 109 .. 263 321 .. 232 344 .. 0.64 4 ! 25.0 0.0 2.1e-08 1.4e-05 53 114 .. 350 412 .. 336 429 .. 0.87 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.77 Beta-prop_WDR3_2nd 182 dissDsklivtgsaDknikiwGldfGDc 209 d s+ +++++ gs + i iw ld D FUN_001367-T1 194 DSSTPGNFVAVGSMEPHIDIWDLDLVDT 221 4455566777777777777777776665 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0016 Beta-prop_WDR3_2nd 215 ahddsvmsvafvpktHyl.fsagkdkkvkyWDadkfekiqtleghagevwalavss.kgkfvvsashDk 281 +h+d+v+++++ p ++ s + d +v WD + + + l+ h+++v++l +++ ++++s Dk FUN_001367-T1 246 GHSDAVLDLSWNPLVRNVlASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPyESQSILTGSFDK 314 566666666666655433034455666666666666666666666666666655431345555555554 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00016 Beta-prop_WDR3_2nd 53 vlv.gtkdGklevldlasaelletieahegavwsvaltp.dekglvtggaDkkvkfwef 109 vl+ g+ d ++ + dl+ + ++ ++ h+++v+s++ +p ++++++tg+ Dk+ k+ + FUN_001367-T1 263 VLAsGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPyESQSILTGSFDKRAKVVDC 321 33225556666666666666666666666666666666645566666666666666554 PP == domain 4 score: 25.0 bits; conditional E-value: 2.1e-08 Beta-prop_WDR3_2nd 53 vlvgtkdGklevldlasaelletieahegavwsvaltpdekgl.vtggaDkkvkfwefelvee 114 lv+t++G++ +d+++ + + t++ah++a+ +al+++ g+ vt++aD++vk+w+++ + FUN_001367-T1 350 FLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVPGClVTASADETVKVWDIQDNKP 412 689**********************************99987538************997654 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 4.8 3.1e+03 179 203 .. 159 183 .. 155 195 .. 0.79 2 ? 0.1 0.0 0.84 5.5e+02 61 95 .. 247 281 .. 229 289 .. 0.62 3 ! 33.5 0.1 5.7e-11 3.7e-08 54 157 .. 283 386 .. 275 387 .. 0.91 4 ! 8.5 0.0 0.0023 1.5 59 96 .. 374 411 .. 371 417 .. 0.93 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 4.8 WD40_RFWD3 179 gaafyeekedeeykpkqlpLeegsl 203 ++++y+e+e ++y+++ + Le+ +l FUN_001367-T1 159 EISVYNEEEGSQYVHHDILLEAFPL 183 578999999***********97664 PP == domain 2 score: 0.1 bits; conditional E-value: 0.84 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsn 95 Hs+a+ dl++n+ ++l s s D ++ l +l++ FUN_001367-T1 247 HSDAVLDLSWNPLVRNVLASGSADCSVILWDLSQP 281 55555555555555555555555555555555443 PP == domain 3 score: 33.5 bits; conditional E-value: 5.7e-11 WD40_RFWD3 54 ssqyiklHskaiRdlaFnseqdslllsaslDktlkltslls.ntvvqtYetdspvWsCcWseddsnylyaGlqnGsvlvfDiRqtssevselekee 148 + ++ H++++ +l++++++ + +l+ s+Dk +k+++ + ++ +++++ +s+v W++ ++ +++ ++nG+v + D+R t+ +v +l++++ FUN_001367-T1 283 PVHLLRHHKDKVQSLQWHPYESQSILTGSFDKRAKVVDCRNpESNIKSWKFNSEVERVLWNHFSPFNFLVSTENGHVFCCDVR-TDDPVYTLKAHD 377 5566778********************************985789*************************************9.899*******99 PP WD40_RFWD3 149 srspvvsLa 157 + p +L+ FUN_001367-T1 378 DAIPGLALS 386 999977775 PP == domain 4 score: 8.5 bits; conditional E-value: 0.0023 WD40_RFWD3 59 klHskaiRdlaFnseqdslllsaslDktlkltsllsnt 96 k H +ai +la +s+ + l++as D t+k+ +++ n+ FUN_001367-T1 374 KAHDDAIPGLALSSQVPGCLVTASADETVKVWDIQDNK 411 569*******************************9985 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 0.1 0.00087 0.57 1 55 [. 247 305 .. 247 318 .. 0.74 2 ? 2.8 0.0 0.26 1.7e+02 1 31 [. 290 323 .. 290 362 .. 0.74 3 ! 17.8 0.0 5.1e-06 0.0034 1 33 [. 376 411 .. 376 415 .. 0.78 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00087 Beta-prop_TEP1_C 1 hsdrisalk...ltddliisAseDrtvKlWdretkkqvGlFvCe.apvlvlevnpnpes 55 hsd++ +l+ l+ +++ s s D +v lWd ++ k v l + + v++l+ p +++ FUN_001367-T1 247 HSDAVLDLSwnpLVRNVLASGSADCSVILWDLSQPKPVHLLRHHkDKVQSLQWHPYESQ 305 6777777753347899********************99998754156888887665544 PP == domain 2 score: 2.8 bits; conditional E-value: 0.26 Beta-prop_TEP1_C 1 hsdrisalklt...ddliisAseDrtvKlWdret 31 h+d++++l+ ++ i++ s D+ K+ d+++ FUN_001367-T1 290 HKDKVQSLQWHpyeSQSILTGSFDKRAKVVDCRN 323 88999999864222689***********998654 PP == domain 3 score: 17.8 bits; conditional E-value: 5.1e-06 Beta-prop_TEP1_C 1 hsdrisalkltddl...iisAseDrtvKlWdretkk 33 h d+i l l +++ +++As D+tvK+Wd +++k FUN_001367-T1 376 HDDAIPGLALSSQVpgcLVTASADETVKVWDIQDNK 411 667777777766533339*************99987 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.4 1.1e-06 0.00069 80 157 .. 238 314 .. 196 342 .. 0.71 2 ! 12.3 0.1 0.00015 0.099 113 167 .. 358 410 .. 340 419 .. 0.65 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1.1e-06 Beta-prop_TEP1_2nd 80 lsslsvlrghtgavtccsfsldGgl.latggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWt..kddllvscssdG 157 + ++ gh av s+++ ++ la+g+ d s+++Wd+++pk+ ll h+d v + W +++ ++++s d FUN_001367-T1 238 KKLQNSEEGHSDAVLDLSWNPLVRNvLASGSADCSVILWDLSQPKPVH----LLRHHKDKVQSLQWHpyESQSILTGSFDK 314 333444579999999999998776559***************988755....45679999999999633456666666665 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00015 Beta-prop_TEP1_2nd 113 sllcWdvrvpkaPvlirsllachrdWvtgcaWtkd..dllvscssdGsvglWdieke 167 ++c dvr+ + Pv + l h d + g a ++ + lv++s+d +v +Wdi+ + FUN_001367-T1 358 HVFCCDVRT-DDPVYT---LKAHDDAIPGLALSSQvpGCLVTASADETVKVWDIQDN 410 567777777.556532...34577777776665542356777777777777777654 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0092 6 31 65 .. 244 278 .. 234 282 .. 0.90 2 ? 3.0 0.0 0.11 72 27 65 .. 283 321 .. 279 338 .. 0.88 3 ! 19.0 0.0 1.6e-06 0.001 9 68 .. 351 410 .. 342 416 .. 0.83 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0092 Beta-prop_WDR75_1st 31 lkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 +gh+d v + np + + s s+d +v lwd FUN_001367-T1 244 EEGHSDAVLDLSWNPLVRNVLASGSADCSVILWDL 278 589*******************************7 PP == domain 2 score: 3.0 bits; conditional E-value: 0.11 Beta-prop_WDR75_1st 27 cvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 vh l+ h+d+v ++ +p + + + s d ++ d FUN_001367-T1 283 PVHLLRHHKDKVQSLQWHPYESQSILTGSFDKRAKVVDC 321 59****************************999888775 PP == domain 3 score: 19.0 bits; conditional E-value: 1.6e-06 Beta-prop_WDR75_1st 9 llcasGdsvkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdg 68 l+ + v +t++ v +lk+h d + G+al + + ++s+d tv++wd d+ FUN_001367-T1 351 LVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVPGCLVTASADETVKVWDIQDN 410 4433333444445689****************************************9996 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.1 2.9e-06 0.0019 32 89 .. 242 300 .. 231 301 .. 0.89 2 ! 7.6 0.0 0.0093 6.1 38 83 .. 334 380 .. 314 389 .. 0.83 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 2.9e-06 ANAPC4_WD40 32 lseekedsevtslaWkpd.GklLavaysdgevrlldvesgklvhslsaksdkitcleWa 89 see+++ +v +l+W+p ++La + +d +v l d ++ k vh l+ ++dk+ +l+W FUN_001367-T1 242 NSEEGHSDAVLDLSWNPLvRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWH 300 467889999*******97368*************************************6 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0093 ANAPC4_WD40 38 dsevtslaWkpdGkl.Lavaysdgevrlldvesgklvhslsaksdki 83 +sev+ + W++ + + v++++g+v +dv + + v +l+a++d+i FUN_001367-T1 334 NSEVERVLWNHFSPFnFLVSTENGHVFCCDVRTDDPVYTLKAHDDAI 380 788999999887665589************************99976 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 3.1 2.1e+03 107 126 .. 197 216 .. 175 221 .. 0.72 2 ! 24.3 0.1 3e-08 1.9e-05 181 339 .. 245 405 .. 235 406 .. 0.83 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 3.1 WD40_Gbeta 107 psgnfvacggldnicsiynl 126 gnfva+g ++ i++l FUN_001367-T1 197 TPGNFVAVGSMEPHIDIWDL 216 45899999999888888776 PP == domain 2 score: 24.3 bits; conditional E-value: 3e-08 WD40_Gbeta 181 vghtgdvmslslapdtr.lfvsgacdasaklwdvreglcrqtfighesdinaiaffp.ngealatgsddatcrlfdlradq.ellvyshdniicgi 273 gh+ v+ ls p +r ++ sg++d+s+ lwd+ + + + h+ ++++ + p + +++ tgs d ++++d r + ++ + ++ + + FUN_001367-T1 245 EGHSDAVLDLSWNPLVRnVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPyESQSILTGSFDKRAKVVDCRNPEsNIKSWKFNSEVERV 340 69************87626789**********************************944689****************865166689999999999 PP WD40_Gbeta 274 tsvafsksgrlllagyddfncnvwdalkadragvlaghdnrvsclgvtddg.mavatgswdsflkiw 339 fs l+ + + c d d + l hd+ + l ++++ ++ t s d +k+w FUN_001367-T1 341 LWNHFSPFNFLVSTENGHVFC--CDVRTDDPVYTLKAHDDAIPGLALSSQVpGCLVTASADETVKVW 405 999999888777665544333..46667899999999999999999887641467799999999999 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0035 2.3 19 135 .. 224 337 .. 219 342 .. 0.79 2 ! 20.3 0.0 4.1e-07 0.00027 29 121 .. 322 409 .. 319 417 .. 0.87 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0035 Beta-prop_WDR41 19 svlaigeeqtknpytelsvl.kehkdivrflvqiddfr..fasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltas 109 +v+++g+++ k +l+ ++h+d v l +r +as + d +v lwd+ + + l+ h +k+ ++ + +s+ ilt s FUN_001367-T1 224 PVVSLGKKKKKKSKKKLQNSeEGHSDAVLDLSWNPLVRnvLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPY------ESQSILTGS 311 6888899999998888886525799999888776666633688899*********999999999999999988866554......466799999 PP Beta-prop_WDR41 110 sdktvivwdiesgrqlkkisdfqstv 135 dk v d+ + k f+s v FUN_001367-T1 312 FDKRAKVVDCRNPESNIKSWKFNSEV 337 99999999998887777777777776 PP == domain 2 score: 20.3 bits; conditional E-value: 4.1e-07 Beta-prop_WDR41 29 knpytelsvlkehkdivrflv.qiddfrfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdies 121 +np ++++ k +++ r l + f f ++++g vf dv+t + ++ l+ h + i ++ s + ++tas+d tv vwdi+ FUN_001367-T1 322 RNPESNIKSWKFNSEVERVLWnHFSPFNFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLAL------SSQVPGCLVTASADETVKVWDIQD 409 79999999999999999998625789*******************************9988864......55667799*************986 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.8 7.1e-09 4.6e-06 92 204 .. 227 344 .. 197 388 .. 0.69 2 ? 0.6 0.0 0.52 3.4e+02 124 145 .. 392 412 .. 373 439 .. 0.75 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 7.1e-09 Beta-prop_Aladin 92 slatrpssssaqvLk..rpghs.pvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgs.kllaatpssvfrvw 180 sl ++ ++s + L+ ++ghs v +++W+p + ++++ +d s+++Wd ++ + v L r v l+w p +s +l+++ + +v FUN_001367-T1 227 SLGKKKKKKSKKKLQnsEEGHSdAVLDLSWNPLVRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYESqSILTGSFDKRAKVV 319 55555555555556511456763799******99988888889*******************************97762699*****999999 PP Beta-prop_Aladin 181 etetWtce..rWtvlkgrvqaacwsp 204 ++++ +++ W+ ++ v+ w FUN_001367-T1 320 DCRNPESNikSWKF-NSEVERVLWNH 344 99876544215654.33444444433 PP == domain 2 score: 0.6 bits; conditional E-value: 0.52 Beta-prop_Aladin 124 lLvsaspvdtsilvWdvaketa 145 +Lv+as +d+++ vWd++ ++ FUN_001367-T1 392 CLVTAS-ADETVKVWDIQDNKP 412 577776.578899999987764 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.1 0.026 17 39 120 .. 207 259 .. 139 282 .. 0.54 2 ! 23.9 0.4 5.6e-08 3.7e-05 39 230 .. 207 410 .. 198 430 .. 0.75 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.026 Beta-prop_EML 39 akphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWd...................wqkgeklaetktskdkvlav 115 ++phi iW d +k+++ + ++++d+vl++ FUN_001367-T1 207 MEPHIDIW------------------------------------------------DldlvdtlqpvvslgkkkkkKSKKKLQNSEEGHSDAVLDL 254 34555555................................................4444444444444333222111112222334455555555 PP Beta-prop_EML 116 efhpl 120 +++pl FUN_001367-T1 255 SWNPL 259 55555 PP == domain 2 score: 23.9 bits; conditional E-value: 5.6e-08 Beta-prop_EML 39 akphiriWdsetletla...vlgkgefergvsclaFskadggkl...........LaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpl 120 ++phi iWd + + tl+ lgk++ +++ l+ s++ + + + s + ++ +Wd ++ + + + +kdkv ++++hp+ FUN_001367-T1 207 MEPHIDIWDLDLVDTLQpvvSLGKKKKKKSKKKLQNSEEGHSDAvldlswnplvrNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPY 302 589******87665554311566777777777777776554443333333332221233345688999**************************** PP Beta-prop_EML 121 dknllvtcG.kkhiaFWtlegkklekkkgifeksekpkyvlclafsengdvitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkd..gtll 213 ++++++t k+ + ++ + + k+ f++ + + vl +fs+ + +++ ++nG+++ + t+ ++++k ah+ ++ l ++++ g+l+ FUN_001367-T1 303 ESQSILTGSfDKRAKVVDCRNPESNIKSWKFNS--EVERVLWNHFSPFNFLVS-TENGHVFCCDVRTDDPVYTLK-AHDDAIPGLALSSQvpGCLV 394 *****9965357788888888888888888875..688999999999887776.78**************99998.******98887776546777 PP Beta-prop_EML 214 sgggkdgkivawdanle 230 ++ d++++ wd + + FUN_001367-T1 395 TA-SADETVKVWDIQDN 410 65.78888888886544 PP >> WD_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, WD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.15 1e+02 131 167 .. 246 282 .. 241 286 .. 0.90 2 ! 10.5 0.1 0.00046 0.3 128 218 .. 286 369 .. 282 373 .. 0.85 3 ! 10.4 0.0 0.00048 0.31 112 164 .. 356 408 .. 343 437 .. 0.83 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.15 WD_LRWD1 131 ahkkaiatlcfspthethlftasydkriilwdigvpn 167 h a+ l ++p l + s d +ilwd+ p+ FUN_001367-T1 246 GHSDAVLDLSWNPLVRNVLASGSADCSVILWDLSQPK 282 5889999999**********************99875 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00046 WD_LRWD1 128 virahkkaiatlcfspthethlftasydkriilwdigvpnhdykfqasqlltlncssvplrlcpvatcpdsfllagceggcgcwdvrldqp 218 ++r hk + +l + p ++t s+dkr + d p+ + k + +s r+ p +fl++ +g + c dvr d+p FUN_001367-T1 286 LLRHHKDKVQSLQWHPYESQSILTGSFDKRAKVVDCRNPESNIKS-------WKFNSEVERVLWNHFSPFNFLVSTENGHVFCCDVRTDDP 369 6899*******************************9999877663.......344455567777888999999999999999****99998 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00048 WD_LRWD1 112 rgmvrllhvragfccsvirahkkaiatlcfspthethlftasydkriilwdig 164 g v vr+ + ++ah ai l++s l+tas d+ + +wdi FUN_001367-T1 356 NGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVPGCLVTASADETVKVWDIQ 408 566777778888888899*********************************96 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.0 0.0037 2.4 6 58 .. 261 314 .. 255 338 .. 0.81 2 ! 13.5 0.0 6.5e-05 0.043 183 252 .. 339 409 .. 325 416 .. 0.80 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0037 Beta-prop_WDR90_POC16_2nd 6 rrqlatvseDetiriWdldtlqqlydfsaseeaPcavafhPsk.qvfacGfssG 58 r+ la s+D ++ +Wdl+ + ++ + +++ ++ +hP + q + G+ + FUN_001367-T1 261 RNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYEsQSILTGSFDK 314 6789999**********************************7525666665555 PP == domain 2 score: 13.5 bits; conditional E-value: 6.5e-05 Beta-prop_WDR90_POC16_2nd 183 kvafspaklkhLlvstssnkllkldaktGrllrevsevhrsacsslavsed..arylltagdkvikvwdysm 252 +v + + + lvst + +++ d +t + ++ h +a+++la+s++ ++ + +++d+++kvwd + FUN_001367-T1 339 RVLWNHFSPFNFLVSTENGHVFCCDVRTDDPVYTLK-AHDDAIPGLALSSQvpGCLVTASADETVKVWDIQD 409 566666667789*****************9999875.7999*******98733456666789*******875 PP >> Beta-prop_RIG_1st RIG first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 2.1 0.17 1.1e+02 198 253 .. 40 96 .. 28 101 .. 0.78 2 ! 13.2 0.1 5.3e-05 0.035 146 196 .. 254 304 .. 237 338 .. 0.82 3 ! 13.2 0.0 5.2e-05 0.034 149 192 .. 346 386 .. 311 430 .. 0.82 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.17 Beta-prop_RIG_1st 198 eeeklnkea.kkaeqwrsrneaeeekakskkaklvkskaaeaddlFDiYnfdhlesE 253 e+e+++++ + + r + ++++k++++k+ l+ + ++ d+ D+Y+ h +sE FUN_001367-T1 40 ETEETEHDVeDGIGNSRGKVSQTKSKSDASKSGLDEDDDNDDIDINDLYDLAHYDSE 96 3333444331446677888899999************999999*******9999987 PP == domain 2 score: 13.2 bits; conditional E-value: 5.3e-05 Beta-prop_RIG_1st 146 lrcSPydenlfAvGTaaGlvlvcdlrkmsivyklrghkseisgLaWrevsl 196 l P n++A G a +v++ dl++ + v+ lr hk+++ +L+W+ + FUN_001367-T1 254 LSWNPLVRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYES 304 55669999**************************************87655 PP == domain 3 score: 13.2 bits; conditional E-value: 5.2e-05 Beta-prop_RIG_1st 149 SPydenlfAvGTaaGlvlvcdlrkmsivyklrghkseisgLaWr 192 SP++ f v T++G v+ cd+r vy+l++h+++i gLa FUN_001367-T1 346 SPFN---FLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALS 386 5554...889*******************************965 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.02 13 135 159 .. 260 284 .. 236 301 .. 0.67 2 ! 6.4 0.1 0.0076 5 97 155 .. 264 323 .. 261 368 .. 0.66 3 ! 11.6 0.0 0.0002 0.13 115 181 .. 368 435 .. 349 444 .. 0.79 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.02 NBCH_WD40 135 dgsvlatGsydttvmvwevlrarss 159 ++vla+Gs d +v++w++++ + FUN_001367-T1 260 VRNVLASGSADCSVILWDLSQPKPV 284 4689999999999999999876654 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0076 NBCH_WD40 97 iscGnwensfqvislsdGrlvqsirqhkdvvscvavts.dgsvlatGsydttvmvwevlr 155 ++ G+ + s + ls+ + v +r+hkd v +++ + + + tGs+d v + + FUN_001367-T1 264 LASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPyESQSILTGSFDKRAKVVDCRN 323 456677777777788888888888888888888877642556678888888776655543 PP == domain 3 score: 11.6 bits; conditional E-value: 0.0002 NBCH_WD40 115 rlvqsirqhkdvvscvavtsdg.svlatGsydttvmvwevlrarssekrvrntqtelsrkdvviaekp 181 + v +++ h d + +a++s+ l+t s d tv vw+++ ++ s +rn q+ + + e p FUN_001367-T1 368 DPVYTLKAHDDAIPGLALSSQVpGCLVTASADETVKVWDIQDNKPSLVTSRNPQMGRLLNTQCCPEAP 435 55778999**********99853699***************999998888888776665555555555 PP >> MIOS_WD40 MIOS, WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.1 0.00068 0.45 49 107 .. 226 279 .. 216 284 .. 0.82 2 ! 9.7 0.0 0.00079 0.51 136 266 .. 283 416 .. 278 445 .. 0.76 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00068 MIOS_WD40 49 tslgqdhnskfkdligkefvpkharqcntlawnpldsnwlaagldkhradfsvliwdic 107 slg+ ++ k k + + h+ + l+wnpl n la+g ad sv++wd+ FUN_001367-T1 226 VSLGKKKKKKSKKKLQN-SEEGHSDAVLDLSWNPLVRNVLASG----SADCSVILWDLS 279 57888877777766543.34678999999************99....69********85 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00079 MIOS_WD40 136 plyelg.qndaclslcwlprdqklllagm.hrnlaifdlrntsq..kmfvntkavqgvtvdpyf.hdrvasfyegqvaiwdlrkfekpvltlteqp 226 p++ l ++d + sl w p + + +l+g + ++d rn k + v+ v + + ++ + s +g+v d+r + pv tl + FUN_001367-T1 283 PVHLLRhHKDKVQSLQWHPYESQSILTGSfDKRAKVVDCRNPESniKSWKFNSEVERVLWNHFSpFNFLVSTENGHVFCCDVRT-DDPVYTLKAHD 377 5555541578999******998887777615667799***975412556666677777776654257789999*********96.89********* PP MIOS_WD40 227 kpltkvawcptrtgllatltrdsniirlydmqhtptpigd 266 + +a g l t + d ++++d+q + FUN_001367-T1 378 DAIPGLALSSQVPGCLVTASADE-TVKVWDIQDNKPSLVT 416 ******************99986.5799999987555544 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 9.9e-07 0.00065 19 131 .. 303 419 .. 294 451 .. 0.85 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 9.9e-07 Beta-prop_ACSF4 19 sselvvvgSHsgkivcvdlet.geviweielpdriEssacvskdgklvvvGcydgklycldlatgeilwkfk.tgdaiKsspvidsesglvvvg 110 +s+ ++ gS++++ +vd ++ ++ i + ++++++E + + +v + +g+++c+d++t + +++ k +dai ++ + g +v + FUN_001367-T1 303 ESQSILTGSFDKRAKVVDCRNpESNIKSWKFNSEVERVLWNHFSPFNFLVSTENGHVFCCDVRTDDPVYTLKaHDDAIPGLALSSQVPGCLVTA 396 67899**************98356788899*******99999999999************************45789***************** PP Beta-prop_ACSF4 111 sydknlyaldvesgk..lvwklk 131 s d+ + ++d++++k lv +++ FUN_001367-T1 397 SADETVKVWDIQDNKpsLVTSRN 419 ***********885511455555 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.4 0.3 0.0001 0.066 50 115 .. 238 304 .. 232 322 .. 0.83 2 ? 0.1 0.0 0.56 3.7e+02 184 218 .. 330 364 .. 315 383 .. 0.82 3 ? 2.7 0.0 0.086 57 288 307 .. 391 410 .. 370 419 .. 0.87 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.0001 Beta-prop_IFT140_1st 50 ekvedakiersvqvtvlsWHP.tkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngs 115 k+++++ +s +v lsW P +++la g + v+++ ++ + +l ++hk +++ l+w s FUN_001367-T1 238 KKLQNSEEGHSDAVLDLSWNPlVRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYES 304 5667777778889999*****5599******************99999**************86544 PP == domain 2 score: 0.1 bits; conditional E-value: 0.56 Beta-prop_IFT140_1st 184 nwkkskkgsllklgsqeelsffvgtadGsvyyvde 218 +wk +++ + + ++ ++f v+t++G+v++ d FUN_001367-T1 330 SWKFNSEVERVLWNHFSPFNFLVSTENGHVFCCDV 364 67777777777777778899***********9875 PP == domain 3 score: 2.7 bits; conditional E-value: 0.086 Beta-prop_IFT140_1st 288 glLitatgesvirlwdlerd 307 g L+ta+ ++++++wd++ + FUN_001367-T1 391 GCLVTASADETVKVWDIQDN 410 789*************9876 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.9 0.1 0.00018 0.12 69 150 .. 236 320 .. 231 345 .. 0.83 2 ? 5.1 0.0 0.021 14 83 153 .. 336 409 .. 322 425 .. 0.71 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00018 Beta-prop_WDR19_1st 69 ntkktskldtglkdkltfllWsk.kspiLavGtskGnlllYnkktskkipilGkHskkItcgaws..kenlLalgseDktltisn 150 ++kk ++ + g d++ l+W ++La G++ +++l++ ++ k + +l H+ k+ + +w+ +++ + +gs Dk + + FUN_001367-T1 236 SKKKLQNSEEGHSDAVLDLSWNPlVRNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHpyESQSILTGSFDKRAKVVD 320 4567788888999999999999637899************************************866778888999999877665 PP == domain 2 score: 5.1 bits; conditional E-value: 0.021 Beta-prop_WDR19_1st 83 kltfllWskkspi.LavGtskGnlllYnkktskkipilGkHskkItcgawske..nlLalgseDktltisnaeG 153 ++ +lW + sp+ v t++G+++ + +t + +l H +I a s++ ++L+++s D+t+ + +++ FUN_001367-T1 336 EVERVLWNHFSPFnFLVSTENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQvpGCLVTASADETVKVWDIQD 409 55566777766643667888888888888888888888888888887777766446788888888888777654 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.013 8.5 88 162 .. 248 321 .. 197 335 .. 0.70 2 ! 10.4 0.0 0.00047 0.31 18 50 .. 388 419 .. 355 432 .. 0.78 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.013 WD40_MABP1-WDR62_2nd 88 knGvRvlkvspdg.khlasGDrsGniriydletleellkieahdsevlcleyskpetglkllasasRDRlihvfdv 162 + v l+ +p + lasG ++ ++dl++ + ++ + h v +l+++ e++ +l ++s D+ +v+d FUN_001367-T1 248 SDAVLDLSWNPLVrNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYESQS-IL-TGSFDKRAKVVDC 321 33444444444431458999999999999999999999999999999999988877553.33.4556666666655 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00047 WD40_MABP1-WDR62_2nd 18 lpagsFltcssDdtiRlWnleeksseetalkrn 50 +g+ +t+s+D+t+++W +++++ + +++rn FUN_001367-T1 388 QVPGCLVTASADETVKVWDIQDNKP-SLVTSRN 419 4578999999999999999988654.4445555 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.1 6.3e-06 0.0041 27 127 .. 200 303 .. 195 367 .. 0.78 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 6.3e-06 Beta-prop_WDR35_TULP_N 27 gyiavggedglLkvLklesekkeaka....kglaaksnlsmnqtlegHsgavqvvaWNekykk.LtssDenGliivWmlykgswvee 108 +++avg + + + +l+ + + + k++++ks+ +++++ egHs+av ++WN + L+s ++ +i+W l + + v FUN_001367-T1 200 NFVAVGSMEPHIDIWDLDLVDTLQPVvslgKKKKKKSKKKLQNSEEGHSDAVLDLSWNPLVRNvLASGSADCSVILWDLSQPKPVHL 286 5888888888888888887443332111224555666667778889************9876538888999*********9998875 PP Beta-prop_WDR35_TULP_N 109 minnrnksvvkdlkWssdg 127 + +k +v++l+W++ + FUN_001367-T1 287 L--RHHKDKVQSLQWHPYE 303 5..4567789999998744 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.2 0.0013 0.83 109 154 .. 245 292 .. 240 321 .. 0.76 2 ? -2.0 0.0 2.8 1.9e+03 246 298 .. 315 367 .. 303 372 .. 0.72 3 ? 4.0 0.0 0.042 27 109 165 .. 374 432 .. 363 453 .. 0.76 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0013 Beta-prop_DCAF12 109 kghkdwifaiaw..lsdtvavsGsrdgtlalwrvdpdklnasialkne 154 +gh+d++ + w l +v sGs d ++ lw + + k + + ++++ FUN_001367-T1 245 EGHSDAVLDLSWnpLVRNVLASGSADCSVILWDLSQPKPVHLLRHHKD 292 79**********77789***************9987765554444444 PP == domain 2 score: -2.0 bits; conditional E-value: 2.8 Beta-prop_DCAF12 246 hvsfldlrqekqnirplcsreggtgvrslsvyqhiitvGtghGsllfydiraq 298 + ++d r+ + ni++ + + v + v t +G ++ +d+r+ FUN_001367-T1 315 RAKVVDCRNPESNIKSWKFNSEVERVLWNHFSPFNFLVSTENGHVFCCDVRTD 367 55678888888888888777666666555555555667889999999999985 PP == domain 3 score: 4.0 bits; conditional E-value: 0.042 Beta-prop_DCAF12 109 kghkdwifaiawlsd..tvavsGsrdgtlalwrvdpdklnasialkneaelpvyahirP 165 k+h d+i +a s+ v+ s d t+ +w ++ +k + ++++ +++ + ++ P FUN_001367-T1 374 KAHDDAIPGLALSSQvpGCLVTASADETVKVWDIQDNKPSLVTSRNPQMGRLLNTQCCP 432 689999998887776224789*************9887665555555555555555555 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.41 2.7e+02 449 477 .. 211 240 .. 200 245 .. 0.79 2 ! 8.9 0.0 0.0012 0.8 358 396 .. 262 300 .. 243 339 .. 0.73 3 ? 2.0 0.0 0.15 1e+02 315 336 .. 389 410 .. 354 420 .. 0.81 4 ? -0.9 0.3 1.1 7.4e+02 143 213 .. 458 531 .. 441 537 .. 0.56 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.41 Beta-prop_SCAP 449 vsfwdlnyGdllqt.vylGksseaqgvrql 477 + wdl+ d lq v lGk ++ ++ ++l FUN_001367-T1 211 IDIWDLDLVDTLQPvVSLGKKKKKKSKKKL 240 678*******99962579999988877665 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0012 Beta-prop_SCAP 358 mvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvct 396 vlasG d ++ lwd+ v + h+ v+sl + FUN_001367-T1 262 NVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWH 300 59**************98888888888889999999874 PP == domain 3 score: 2.0 bits; conditional E-value: 0.15 Beta-prop_SCAP 315 aaGrvvtGsqdhtvrvyrleds 336 G +vt s d tv+v+ ++d FUN_001367-T1 389 VPGCLVTASADETVKVWDIQDN 410 45899***********999885 PP == domain 4 score: -0.9 bits; conditional E-value: 1.1 Beta-prop_SCAP 143 verayeeheassvlspalsspspgaslssae....eeeaesaeksspaasaaadlessvwslelqGnliaaGrss 213 v+r +e +e v++pa++ ++p++++ + ee+a+ +k+ p++ ++++ ++ +l l+ ++ +G s+ FUN_001367-T1 458 VQRHFESRERL-VQTPASNASTPKNTSDLNSedevEETADDLSKENPENMEEESAAVAMAALTLKSSVRNSGNSK 531 55555555433.333333333333222222200013444445666666666777777777888888877777776 PP >> Beta-prop_LRRK2 LRRK2 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.0 0.0029 1.9 74 118 .. 261 305 .. 217 313 .. 0.85 2 ? 1.3 0.0 0.29 1.9e+02 289 320 .. 352 383 .. 345 395 .. 0.74 3 ? -2.5 0.0 4.1 2.7e+03 229 245 .. 396 412 .. 383 415 .. 0.82 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0029 Beta-prop_LRRK2 74 edwlvaGtqsgslvvidtedkevkhslqkltDaVtsLlfhskskr 118 ++l G +s+++ d ++ + +h l++ +D V sL +h +++ FUN_001367-T1 261 RNVLASGSADCSVILWDLSQPKPVHLLRHHKDKVQSLQWHPYESQ 305 578999**********************************87554 PP == domain 2 score: 1.3 bits; conditional E-value: 0.29 Beta-prop_LRRK2 289 iGtggGhillldlstrqllqvisrhcdsvRsl 320 + t++Gh+ d+ t +++ +++ h d++ l FUN_001367-T1 352 VSTENGHVFCCDVRTDDPVYTLKAHDDAIPGL 383 55777888888888888887777777776554 PP == domain 3 score: -2.5 bits; conditional E-value: 4.1 Beta-prop_LRRK2 229 kknspvvevWdkksekl 245 +++v vWd++++k FUN_001367-T1 396 ASADETVKVWDIQDNKP 412 456789*****999885 PP >> WDR54 WDR54 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00031 0.2 230 288 .. 355 414 .. 348 447 .. 0.81 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00031 WDR54 230 gngqvhlyeattgnlhvqinaharaicaldlasev.gkllsagedtfvhiwklsrnpesg 288 ng+v+ + t + ++ah ai l l+s+v g l++a d v++w + n s FUN_001367-T1 355 ENGHVFCCDVRTDDPVYTLKAHDDAIPGLALSSQVpGCLVTASADETVKVWDIQDNKPSL 414 689999999999999999****************978999***********998886654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (539 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1718 (0.0672539); expected 510.9 (0.02) Passed bias filter: 821 (0.0321394); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 39 [number of targets reported over threshold] # CPU time: 0.53u 0.37s 00:00:00.90 Elapsed: 00:00:00.44 # Mc/sec: 4897.43 // Query: FUN_001368-T1 [L=265] Description: FUN_001368 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-28 96.9 34.8 1.6e-06 29.3 2.0 6.5 6 SHIPPO-rpt Sperm-tail PG-rich repeat Domain annotation for each model (and alignments): >> SHIPPO-rpt Sperm-tail PG-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.1 7.4e-08 0.0019 1 33 [] 34 70 .. 34 70 .. 0.86 2 ! 7.0 0.5 0.00086 22 13 31 .. 86 104 .. 75 106 .. 0.76 3 ! 29.3 2.0 6.4e-11 1.6e-06 1 32 [. 111 141 .. 111 142 .. 0.90 4 ! 10.2 0.3 7.8e-05 2 1 30 [. 147 178 .. 147 180 .. 0.85 5 ! 24.0 0.7 3.2e-09 8.1e-05 1 30 [. 190 217 .. 190 220 .. 0.88 6 ! 28.1 1.5 1.5e-10 3.8e-06 2 31 .. 227 254 .. 226 256 .. 0.94 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 7.4e-08 SHIPPO-rpt 1 tPGPGaYnpek......psvkkkkksapaysfgsrtrrf 33 +PGP +Y + ++ +k+ + pa+sfg+r++ f FUN_001368-T1 34 GPGPAKYLLPGtiglkgHDIRKQ--RCPAFSFGQRHKEF 70 6**************55555555..***********975 PP == domain 2 score: 7.0 bits; conditional E-value: 0.00086 SHIPPO-rpt 13 svkkkkksapaysfgsrtr 31 ++k + +apa+s+ srtr FUN_001368-T1 86 ATRKGRETAPAFSLHSRTR 104 55667779*********98 PP == domain 3 score: 29.3 bits; conditional E-value: 6.4e-11 SHIPPO-rpt 1 tPGPGaYnpek.psvkkkkksapaysfgsrtrr 32 tPGPG+Y+pek ++ +k +ap+y+f++rt++ FUN_001368-T1 111 TPGPGQYSPEKcHPPQEK--RAPCYTFKTRTKY 141 8**********7777777..9**********96 PP == domain 4 score: 10.2 bits; conditional E-value: 7.8e-05 SHIPPO-rpt 1 tPGPGaYnpek....psvkkkkksapaysfgsrt 30 tP P +Y+ + + v + sapa s++ r+ FUN_001368-T1 147 TPSPNSYSLPPmigpKVVSAQ--SAPAHSLSARS 178 8************65555555..********997 PP == domain 5 score: 24.0 bits; conditional E-value: 3.2e-09 SHIPPO-rpt 1 tPGPGaYnpekpsvkkkkksapaysfgsrt 30 tPGPG+Y+++ p++ ++ pay++++r+ FUN_001368-T1 190 TPGPGTYEVTHPNTNRR--QMPAYTMNGRN 217 8**********666666..*********97 PP == domain 6 score: 28.1 bits; conditional E-value: 1.5e-10 SHIPPO-rpt 2 PGPGaYnpekpsvkkkkksapaysfgsrtr 31 PGPG+++pek v+ +k++ap++sfg r++ FUN_001368-T1 227 PGPGQHSPEK--VVYNKPTAPKFSFGVRHS 254 **********..****************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (265 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 451 (0.0176551); expected 510.9 (0.02) Passed bias filter: 370 (0.0144842); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2666.77 // Query: FUN_001369-T1 [L=915] Description: FUN_001369 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-40 137.7 1.6 1e-37 130.5 1.6 2.4 1 ANF_receptor Receptor family ligand binding region 6.9e-37 127.0 0.3 1.7e-36 125.7 0.3 1.7 1 Lig_chan Ligand-gated ion channel 3.7e-30 104.9 0.0 1.6e-29 102.8 0.0 2.0 2 Lig_chan-Glu_bd Ligated ion channel L-glutamate- and glycine 1.3e-14 54.6 5.6 2.8e-14 53.6 5.6 1.6 1 CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA recepto 3.9e-12 46.5 0.0 4.2e-11 43.2 0.0 2.4 1 SBP_bac_3 Bacterial extracellular solute-binding prote 7.5e-06 26.3 0.0 1.2e-05 25.6 0.0 1.2 1 Peripla_BP_6 Periplasmic binding protein 0.00013 22.3 0.4 0.00013 22.3 0.4 2.0 2 Ion_trans_2 Ion channel 0.0049 17.4 1.2 0.019 15.5 0.5 2.1 2 DUF350 Domain of Unknown Function (DUF350) ------ inclusion threshold ------ 0.049 13.9 0.3 0.17 12.1 0.2 2.0 2 UBA_ARI1 E3 ubiquitin-protein ligase ARIH1, UBA-like Domain annotation for each model (and alignments): >> ANF_receptor Receptor family ligand binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.5 1.6 3.6e-41 1e-37 9 351 .. 47 359 .. 43 361 .. 0.86 Alignments for each domain: == domain 1 score: 130.5 bits; conditional E-value: 3.6e-41 ANF_receptor 9 Avedinsdpsllpgt.klevii.ldtccdpslaleaaldllkgevaaiiGpsss...svasavaslanefkvpvisygstspelsdknryptflrt 99 Av++i +d+s +t k+++ + +++ + a++++ + +++ v+a+i ++ + s + ++ ++ +++pvi+ ++ +sdk+ ++tflrt FUN_001369-T1 47 AVKKIDADSSNVFKTaKFNASSsVLSPNPIHSAMNVCEKVIAKGVVAVIVSHPKddtSPPISISYACSFYHIPVIGISARETIFSDKSLHDTFLRT 142 788888887777666699999999999***************98888888443321366688999**************9999************* PP ANF_receptor 100 vpsdtsqakAiadilkhfgWkrvaliysdddygesglqaleealrergirvalkavippsqdddeivrkllkevkskearvivlcasseearrllk 195 vps + qa + + +l+hf+W++v+l++s+d + + ++ +++ ++++ i++ ++ + +++ +l k++k+ +++vi++ as+e+a+ + + FUN_001369-T1 143 VPSYSDQAYVWLGLLRHFRWNKVILLTSNDQDSRMIATKFTGLAERNKIKIEKTILFQ--TGCVNATSQLVKLIKM-QSQVILFSASEEDATVVYQ 235 ****************************************************999999..34559***********.******************* PP ANF_receptor 196 aarelgmmgeeyvwiatdglttslvidkpsdlttleaaegvlgfrlhepespefsefvekeklskekenyenlgklqvsyalaaYDavyllAhAle 291 a +lg++ ++yvw++t++ t +++ e+ +g++g+rl s + n + s ++ Dav l+A+A++ FUN_001369-T1 236 NAFQLGITRRGYVWLVTEQSFT--------GTARNELPQGAVGMRL----SYG------------------NNE----SAQV--QDAVSLVAKAIN 295 ***************6555111........2233345566666665....111..................222....3333..5*********** PP ANF_receptor 292 ellrkd....ksgslacgalkpwnggqsllrylknvnfk.GltGevqfdengdrinpdydilnlk 351 +ll ++ ++ s +c++ ++w++gq l ++l n++ + G tG++ ++ ngdrin+ y+ilnlk FUN_001369-T1 296 RLLAANrsltPPTS-SCKETSQWDSGQILFHELVNTTLEnGRTGKLLLNGNGDRINSVYQILNLK 359 ***99999986666.9*********************99899*********************97 PP >> Lig_chan Ligand-gated ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 125.7 0.3 6e-40 1.7e-36 2 146 .] 565 829 .. 564 829 .. 0.96 Alignments for each domain: == domain 1 score: 125.7 bits; conditional E-value: 6e-40 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Lig_chan 2 levWllilvalllvavvlfllerlspyewrepe..eeeeneftlsnslwfvlgalvqqg.aeekpkslsaRivvavWwffvlillssYtAnLaafl 94 +++Wll+l+++++vav+l+ll+r+sp++ + + e+ee+ +ls+++wf++g+l+++g +e +p+s+saR++++vW+ f++i+++sYtAnLaafl FUN_001369-T1 565 INLWLLVLLSVHIVAVILYLLDRFSPFGRFKLArkEKEETALNLSSAMWFSWGVLLNSGiGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFL 660 689************************98888765669*********************999********************************** PP xxxxxxxxxxxxxx..xxxxx........................................................................... RF Lig_chan 95 tverlqspiksled..Lakqe........................................................................... 113 +++r + +++++d L++ + FUN_001369-T1 661 VLDRPKAVVSGIDDpnLRNPSgdfkyatvanssvdayfrrqvelssmytfmekynvktareaiqkvknnelkafiwdspvlyyeasqdcmltiage 756 **************888866679************************************************************************* PP ...........................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Lig_chan 114 ...........................................kaeCeskssasksskeLslkslaglFlvlligl 146 +++C ++s+++++ L+l+++ g+F+++++g+ FUN_001369-T1 757 lfgrsgygigmpkgspwtnnislailnfhesgvmeelettwidSKNCAEQSNSPAT---LGLSHMLGVFIMVAAGI 829 ******************************************9779**99999998...**************996 PP >> Lig_chan-Glu_bd Ligated ion channel L-glutamate- and glycine-binding site # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.3 3.7e+03 2 17 .. 401 416 .. 400 430 .. 0.77 2 ! 102.8 0.0 5.6e-33 1.6e-29 22 114 .. 453 550 .. 438 551 .. 0.89 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.3 Lig_chan-Glu_bd 2 tlkvvtileePyvmlk 17 +l+vvt++ eP+v ++ FUN_001369-T1 401 HLNVVTLVGEPFVFIT 416 7899********9964 PP == domain 2 score: 102.8 bits; conditional E-value: 5.6e-33 Lig_chan-Glu_bd 22 legner.yeGfcidllkelakklgfkyelklvkdgkyGslkektk....eWnGligellekkadlavadltitaeReevvdFtkpfmelgisil 110 +++n++ + Gfc+dllk+lakk++f+++++l++dg+yGsl++ ++ +WnG++ge++++k dl+va+lti++eR+e ++F+kpf +g++il FUN_001369-T1 453 SDKNDHcCYGFCMDLLKRLAKKVNFTFDVHLSEDGSYGSLRRVNGtdmkRWNGMVGEVIDDKSDLIVAALTINNERAEWIEFSKPFKYQGLTIL 546 45554459*******************************99876544548******************************************** PP Lig_chan-Glu_bd 111 ikkp 114 +kk+ FUN_001369-T1 547 VKKD 550 **97 PP >> CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.6 5.6 9.7e-18 2.8e-14 1 29 [] 840 868 .. 840 868 .. 0.98 Alignments for each domain: == domain 1 score: 53.6 bits; conditional E-value: 9.7e-18 CaM_bdg_C0 1 ivYKKHqirKqkklElARhaaDKWRGaIe 29 i+Y+KH+++K++++E+A++++DKWR++I+ FUN_001369-T1 840 ILYHKHRGWKEEQKEIAKKTTDKWRANIL 868 89*************************96 PP >> SBP_bac_3 Bacterial extracellular solute-binding proteins, family 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.2 0.0 1.5e-14 4.2e-11 43 131 .. 498 799 .. 450 800 .. 0.93 Alignments for each domain: == domain 1 score: 43.2 bits; conditional E-value: 1.5e-14 xx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx....................................... RF SBP_bac_3 43 vp.vsfdelipalksgkvDvviagmtitpeRkkkvdfsqpy.lsgqvllvrkgskki....................................... 97 ++ ++++++ ++ + k D+++a++ti+ eR++ ++fs+p+ ++g ++lv+k++++ FUN_001369-T1 498 TDmKRWNGMVGEVIDDKSDLIVAALTINNERAEWIEFSKPFkYQGLTILVKKDQSSNrldsflrpfqinlwllvllsvhivavilylldrfspfgr 593 55468************************************667*********9974679************************************ PP ................................................................................................ RF SBP_bac_3 98 ................................................................................................ 97 FUN_001369-T1 594 fklarkekeetalnlssamwfswgvllnsgigegtprsfsarvlgmvwagfamiivasytanlaaflvldrpkavvsgiddpnlrnpsgdfkyatv 689 ************************************************************************************************ PP .............................................................................xxxxxxxxxxxxxxxxxxx RF SBP_bac_3 98 .............................................................................vrkgdpellaavnkalael 116 ++kg+p + + + a+ + FUN_001369-T1 690 anssvdayfrrqvelssmytfmekynvktareaiqkvknnelkafiwdspvlyyeasqdcmltiagelfgrsgygigMPKGSP-WTNNISLAILNF 784 **********************************************************************************8.************ PP xxxxxxxxxxxxxxx RF SBP_bac_3 117 kadgtlakiyekwfg 131 +++g +++++ w+ FUN_001369-T1 785 HESGVMEELETTWID 799 *************85 PP >> Peripla_BP_6 Periplasmic binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.0 4.2e-09 1.2e-05 62 250 .. 84 275 .. 76 301 .. 0.78 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 4.2e-09 Peripla_BP_6 62 rklvdqegvdaiigglssavalavae..vlak.kgvpvig.psglt...gekcspnvfslgpttsaqaaalvdylakelggkkvaligadyafgra 150 +k ++ +gv+a+i ++ ++++ + +++ ++pvig ++++t +++ ++++ ++ p++s+qa +++ l +++ +kv l++++ + +r FUN_001369-T1 84 EKVIA-KGVVAVIVSHPKDDTSPPISisYACSfYHIPVIGiSARETifsDKSLHDTFLRTVPSYSDQAYVWLG-LLRHFRWNKVILLTSNDQDSRM 177 55556.555555555555555553332244444689****544444554789999999***************.67779***************** PP Peripla_BP_6 151 leaaakaalkaaGgkvvgevrvplgttDfssvvlqikasgadavllalagadavnllkqaaeaGlkakgiklvallldesdlkalggdaa.egvyv 245 ++++++ ++++ +k+ +++ ++ g + +s++ ++ + + +++l+ + da+ +++ a + G++++ + +l++e+ +++ + + +g+++ FUN_001369-T1 178 IATKFTGLAERNKIKIEKTILFQTGCVNATSQLVKLIKMQSQVILFSASEEDATVVYQNAFQLGITRR---GYVWLVTEQSFTGTARNELpQGAVG 270 ******************************************************************86...6688888888888777655456555 PP Peripla_BP_6 246 ttayf 250 + + FUN_001369-T1 271 MRLSY 275 54444 PP >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.4 4.5e-08 0.00013 2 77 .. 571 660 .. 570 662 .. 0.89 2 ? -5.6 2.7 9 2.6e+04 53 72 .. 821 840 .. 818 842 .. 0.78 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 4.5e-08 Ion_trans_2 2 vlllvlifgtviyll................eegwegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllflavlgevl 77 vll v i ++++yll ee+ +++++a++fs+ +l+ G G+ +Pr+ r++ +v++ + +++++ ++a+l+ +l FUN_001369-T1 571 VLLSVHIVAVILYLLdrfspfgrfklarkekEET--ALNLSSAMWFSWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFL 660 6788889999999999999999999999654333..56************************9999**********************9998 PP == domain 2 score: -5.6 bits; conditional E-value: 9 Ion_trans_2 53 lftivyiliGiplfllflav 72 +f++v + iG ++++++l + FUN_001369-T1 821 VFIMVAAGIGAGVVIIILEI 840 57888888999988888765 PP >> DUF350 Domain of Unknown Function (DUF350) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.5 6.7e-06 0.019 8 95 .. 566 660 .. 557 678 .. 0.70 2 ? -0.9 0.0 0.79 2.2e+03 53 66 .. 817 830 .. 798 858 .. 0.60 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6.7e-06 DUF350 8 aflvyflvglvllvlgllvydlltpydereliregnvAaaislagal.lglalilaaaisgsas......lldfllwgliglvllllafl.lvdkl 95 ++++ +l+++ ++++ l+++d++ p+ ++l r+ +a+ l++a+ ++ ++ l++ i + + + ++w+ +++++++ l+ l FUN_001369-T1 566 NLWLLVLLSVHIVAVILYLLDRFSPFGRFKLARKEKEETALNLSSAMwFSWGVLLNSGIGE-GTprsfsaRVLGMVWAGFAMIIVASYTAnLAAFL 660 7889999**********************************999887589*********54.3334444544444443333333322222133333 PP == domain 2 score: -0.9 bits; conditional E-value: 0.79 DUF350 53 allglalilaaais 66 ++lg+ +++aa i FUN_001369-T1 817 HMLGVFIMVAAGIG 830 44444444444442 PP >> UBA_ARI1 E3 ubiquitin-protein ligase ARIH1, UBA-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.2 6e-05 0.17 24 35 .. 156 167 .. 155 170 .. 0.84 2 ? -2.6 0.0 2.4 6.9e+03 6 17 .. 348 359 .. 347 361 .. 0.82 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 6e-05 UBA_ARI1 24 LLrhfkWnkEkL 35 LLrhf+Wnk L FUN_001369-T1 156 LLRHFRWNKVIL 167 9*******9665 PP == domain 2 score: -2.6 bits; conditional E-value: 2.4 UBA_ARI1 6 eIdeVssiLglp 17 I+ V +iL+l+ FUN_001369-T1 348 RINSVYQILNLK 359 699999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (915 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 932 (0.0364846); expected 510.9 (0.02) Passed bias filter: 710 (0.0277941); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.43u 0.41s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 8719.70 // Query: FUN_001370-T1 [L=866] Description: FUN_001370 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-59 201.1 20.3 3.5e-59 200.6 20.3 1.2 1 7tm_2 7 transmembrane receptor (Secretin family) 9.6e-16 58.9 6.2 3e-15 57.3 0.3 2.6 2 Lectin_C Lectin C-type domain 2.2e-15 57.4 2.5 5.5e-15 56.1 2.5 1.8 1 GPS GPCR proteolysis site, GPS, motif 1.8e-08 34.4 13.1 2.8e-08 33.7 13.1 1.3 1 Dicty_CAR Slime mold cyclic AMP receptor ------ inclusion threshold ------ 0.68 10.4 2.7 0.55 10.7 1.0 1.7 1 DUF7942 Family of unknown function (DUF7942) Domain annotation for each model (and alignments): >> 7tm_2 7 transmembrane receptor (Secretin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 200.6 20.3 6.8e-63 3.5e-59 3 246 .. 633 863 .. 631 866 .] 0.98 Alignments for each domain: == domain 1 score: 200.6 bits; conditional E-value: 6.8e-63 7tm_2 3 slkvittvGlslSlvaLlvalailllfrklrctrnyihlnLflslilrallvlvkdealkneedqseaeaekvgCkvvavllhYfvlanfaWllvE 98 +l+vit+vG+slSl+ ++++++l++++ r++ ++ihlnL+++l +++++l ++ea++n k++Ck+vavllhYf l++f+W+l+E FUN_001370-T1 633 ALEVITYVGCSLSLLGEILTILTLIFLKLTRSETSVIHLNLVAALAAAQIIFLTGIEATQN----------KAACKIVAVLLHYFNLVSFTWMLIE 718 799**********************************************************..........************************* PP 7tm_2 99 glylytllvevffserkalkkylliGwGvPalvvaiwavvdakgylederCWlsneekllwiikgPvllvilvNfvlfinivrilvsklkesqkkk 194 g+ ly+++v+vf++ ++++kky++ wG+P+++v+i + ++ +gy++++ CWls +++++w++ +Pvll+ l N +++ +++r +++ + ++++ FUN_001370-T1 719 GIWLYVMIVRVFENGHSRIKKYCACAWGIPFVFVVITLSASFDGYGTNTSCWLSVQKGTIWSFVVPVLLIALANSIILGMVMREILRLNQPATTEN 814 **************************************************************************************9999999999 PP 7tm_2 195 kdlkkalklvkstllllpLlgvtwvlglfavnpeevlsevflylelilnslq 246 ++++++ +ks+ +llpLlg+tw++g++++n+e+ ++f+yl++++nslq FUN_001370-T1 815 FKYQTVRCGAKSATVLLPLLGITWIFGVLTFNSET---VAFQYLFATFNSLQ 863 999989999**************************...*************9 PP >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.3 0.3 5.9e-19 3e-15 2 106 .. 50 161 .. 49 162 .. 0.95 2 ? 3.7 1.0 0.028 1.4e+02 48 100 .. 542 596 .. 516 607 .. 0.83 Alignments for each domain: == domain 1 score: 57.3 bits; conditional E-value: 5.9e-19 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllk....ksnkkfWigltdeksegtwkwedgskvnteeytnwepnnngenedCvel.....eks 88 +k+w +a++ C k gg+Lv+++++ +++f+++ ++ ++++ +igl ++ s ++w+w++g+++ t ++w+pn+ ++++ Cv++ + + FUN_001370-T1 50 TKKWPDAKNECVKDGGHLVVLETESKWRFIKEEIQnlqnPTSNEWFIGL-SNASGNDWRWITGEPLITG--QHWQPNEPSGDGRCVVIakdypRGT 142 689*****************************99999988888999***.999**************85..78*******************99** PP Lectin_C 89 sgkwndesCns.knpfvCe 106 +g nd sCn k++f+C+ FUN_001370-T1 143 QGLFNDLSCNGhKKAFICQ 161 **********9899****7 PP == domain 2 score: 3.7 bits; conditional E-value: 0.028 Lectin_C 48 deksegtwkwedgskvnteeytnwepnnngenedCvel......ekssgkwndesCnsk 100 + s+++++ + ++++++y + ++++ +C+ + ++ +g+w++e C++ FUN_001370-T1 542 FQTSNKSFRGKVTIQLSHTKY----QGSDKKTMQCAFWqnskrpKNPNGYWSTEGCYKD 596 566677777777777777766....68999999***99999999999*********985 PP >> GPS GPCR proteolysis site, GPS, motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.1 2.5 1.1e-18 5.5e-15 2 45 .] 571 618 .. 570 618 .. 0.88 Alignments for each domain: == domain 1 score: 56.1 bits; conditional E-value: 1.1e-18 GPS 2 qCvfWd...ssnsgtggWsteGC.sltessnethtvCsCnHltsFAvL 45 qC+fW+ ++ g WsteGC + + sn++ tvC+CnHlt+FA+L FUN_001370-T1 571 QCAFWQnskRPKNPNGYWSTEGCyKDEQLSNAQATVCHCNHLTNFAIL 618 9******99666678********85566779****************8 PP >> Dicty_CAR Slime mold cyclic AMP receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.7 13.1 5.6e-12 2.8e-08 13 221 .. 637 843 .. 625 862 .. 0.78 Alignments for each domain: == domain 1 score: 33.7 bits; conditional E-value: 5.6e-12 Dicty_CAR 13 vllladfssilgcllvligfwrlkllrnhitkvialfcatsllkdlistiltlleeaqesgfpcylyaivitygslacwlwtlclalsiynlivkr 108 + + s+lg +l ++++ lkl r t vi l +++l+ i + lt + ea+++ c + a+ + y l + w l+ + +y++iv+ FUN_001370-T1 637 ITYVGCSLSLLGEILTILTLIFLKLTRSE-TSVIHLNLVAALAAAQI-IFLTGI-EATQNKAACKIVAVLLHYFNLVSFTWMLIEGIWLYVMIVRV 729 45555556899999999999999999987.78999988888876543.344444.55667789********************************9 PP Dicty_CAR 109 epepekfekyyfvlcwglplistivmlskevievvgn.wcwigekyvgyrfglfygpfliiwaisavlvgltsrytykvirnsvsdn.kdkhltyq 202 + k y + wg+p++ +++ ls + + n cw++ + + + f +p l+i ++++g+ r ++ + + ++n k + + FUN_001370-T1 730 FENGHSRIKKYCACAWGIPFVFVVITLSASFDGYGTNtSCWLSVQKGT--IWSFVVPVLLIALANSIILGMVMREILRLNQPATTENfKYQTVRCG 823 888877777788899*************99877654427***988543..456899*****************99999888887777344555556 PP Dicty_CAR 203 fklinyiivfl.vcwvfavv 221 k ++ +l + w+f v+ FUN_001370-T1 824 AKSATVLLPLLgITWIFGVL 843 66666555444467777775 PP >> DUF7942 Family of unknown function (DUF7942) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 1.0 0.00011 0.55 26 99 .. 723 803 .. 704 808 .. 0.67 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00011 DUF7942 26 wvlvdtllvdhedasfagvwplllTaPtsllll.ll.......lpgeeas.gaaalsawlfvlavalgalvnAvllgalaral 99 +v+++ ++ ++ + + + + P++++++ l + ++ + + ++ + w fv+ v+l al+n+++lg+++r + FUN_001370-T1 723 YVMIVRVF-ENGHSRIKKYCACAWGIPFVFVVItLSasfdgygT-NTSCWlSVQKGTIWSFVVPVLLIALANSIILGMVMREI 803 55555555.45555566666777777888776545444443311.233330344556679*******************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (866 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 947 (0.0370718); expected 510.9 (0.02) Passed bias filter: 548 (0.0214523); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.40u 0.42s 00:00:00.82 Elapsed: 00:00:00.43 # Mc/sec: 8107.73 // Query: FUN_001370-T2 [L=939] Description: FUN_001370 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-62 210.5 20.9 4.6e-62 210.0 20.9 1.2 1 7tm_2 7 transmembrane receptor (Secretin family) 1.2e-15 58.6 6.2 3.4e-15 57.2 0.3 2.6 2 Lectin_C Lectin C-type domain 2.4e-15 57.2 2.5 6e-15 56.0 2.5 1.7 1 GPS GPCR proteolysis site, GPS, motif 4.8e-08 33.0 15.2 7.8e-08 32.3 15.2 1.3 1 Dicty_CAR Slime mold cyclic AMP receptor ------ inclusion threshold ------ 1.3 9.5 3.4 0.47 10.9 0.6 1.7 2 DUF7942 Family of unknown function (DUF7942) Domain annotation for each model (and alignments): >> 7tm_2 7 transmembrane receptor (Secretin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 210.0 20.9 8.9e-66 4.6e-62 3 250 .] 633 867 .. 631 867 .. 0.98 Alignments for each domain: == domain 1 score: 210.0 bits; conditional E-value: 8.9e-66 7tm_2 3 slkvittvGlslSlvaLlvalailllfrklrctrnyihlnLflslilrallvlvkdealkneedqseaeaekvgCkvvavllhYfvlanfaWllvE 98 +l+vit+vG+slSl+ ++++++l++++ r++ ++ihlnL+++l +++++l ++ea++n k++Ck+vavllhYf l++f+W+l+E FUN_001370-T2 633 ALEVITYVGCSLSLLGEILTILTLIFLKLTRSETSVIHLNLVAALAAAQIIFLTGIEATQN----------KAACKIVAVLLHYFNLVSFTWMLIE 718 799**********************************************************..........************************* PP 7tm_2 99 glylytllvevffserkalkkylliGwGvPalvvaiwavvdakgylederCWlsneekllwiikgPvllvilvNfvlfinivrilvsklkesqkkk 194 g+ ly+++v+vf++ ++++kky++ wG+P+++v+i + ++ +gy++++ CWls +++++w++ +Pvll+ l N +++ +++r +++ + ++++ FUN_001370-T2 719 GIWLYVMIVRVFENGHSRIKKYCACAWGIPFVFVVITLSASFDGYGTNTSCWLSVQKGTIWSFVVPVLLIALANSIILGMVMREILRLNQPATTEN 814 **************************************************************************************9999999999 PP 7tm_2 195 kdlkkalklvkstllllpLlgvtwvlglfavnpeevlsevflylelilnslqGlfv 250 ++++++ +ks+ +llpLlg+tw++g++++n+e+ ++f+yl++++nslqG+f+ FUN_001370-T2 815 FKYQTVRCGAKSATVLLPLLGITWIFGVLTFNSET---VAFQYLFATFNSLQGFFI 867 999989999**************************...*****************8 PP >> Lectin_C Lectin C-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.2 0.3 6.6e-19 3.4e-15 2 106 .. 50 161 .. 49 162 .. 0.95 2 ? 3.6 1.0 0.031 1.6e+02 48 100 .. 542 596 .. 516 607 .. 0.83 Alignments for each domain: == domain 1 score: 57.2 bits; conditional E-value: 6.6e-19 Lectin_C 2 kksweeaqelCqkeggkLvsinskeenkflssllk....ksnkkfWigltdeksegtwkwedgskvnteeytnwepnnngenedCvel.....eks 88 +k+w +a++ C k gg+Lv+++++ +++f+++ ++ ++++ +igl ++ s ++w+w++g+++ t ++w+pn+ ++++ Cv++ + + FUN_001370-T2 50 TKKWPDAKNECVKDGGHLVVLETESKWRFIKEEIQnlqnPTSNEWFIGL-SNASGNDWRWITGEPLITG--QHWQPNEPSGDGRCVVIakdypRGT 142 689*****************************99999988888999***.999**************85..78*******************99** PP Lectin_C 89 sgkwndesCns.knpfvCe 106 +g nd sCn k++f+C+ FUN_001370-T2 143 QGLFNDLSCNGhKKAFICQ 161 **********9899****7 PP == domain 2 score: 3.6 bits; conditional E-value: 0.031 Lectin_C 48 deksegtwkwedgskvnteeytnwepnnngenedCvel......ekssgkwndesCnsk 100 + s+++++ + ++++++y + ++++ +C+ + ++ +g+w++e C++ FUN_001370-T2 542 FQTSNKSFRGKVTIQLSHTKY----QGSDKKTMQCAFWqnskrpKNPNGYWSTEGCYKD 596 566677777777777777766....68999999***99999999999*********985 PP >> GPS GPCR proteolysis site, GPS, motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.0 2.5 1.2e-18 6e-15 2 45 .] 571 618 .. 570 618 .. 0.88 Alignments for each domain: == domain 1 score: 56.0 bits; conditional E-value: 1.2e-18 GPS 2 qCvfWd...ssnsgtggWsteGC.sltessnethtvCsCnHltsFAvL 45 qC+fW+ ++ g WsteGC + + sn++ tvC+CnHlt+FA+L FUN_001370-T2 571 QCAFWQnskRPKNPNGYWSTEGCyKDEQLSNAQATVCHCNHLTNFAIL 618 9******99666678********85566779****************8 PP >> Dicty_CAR Slime mold cyclic AMP receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.3 15.2 1.5e-11 7.8e-08 13 222 .. 637 844 .. 625 882 .. 0.77 Alignments for each domain: == domain 1 score: 32.3 bits; conditional E-value: 1.5e-11 Dicty_CAR 13 vllladfssilgcllvligfwrlkllrnhitkvialfcatsllkdlistiltlleeaqesgfpcylyaivitygslacwlwtlclalsiynlivkr 108 + + s+lg +l ++++ lkl r t vi l +++l+ i + lt + ea+++ c + a+ + y l + w l+ + +y++iv+ FUN_001370-T2 637 ITYVGCSLSLLGEILTILTLIFLKLTRSE-TSVIHLNLVAALAAAQI-IFLTGI-EATQNKAACKIVAVLLHYFNLVSFTWMLIEGIWLYVMIVRV 729 45555556899999999999999999987.78999988888876543.344444.55667789********************************9 PP Dicty_CAR 109 epepekfekyyfvlcwglplistivmlskevievvgn.wcwigekyvgyrfglfygpfliiwaisavlvgltsrytykvirnsvsdn.kdkhltyq 202 + k y + wg+p++ +++ ls + + n cw++ + + + f +p l+i ++++g+ r ++ + + ++n k + + FUN_001370-T2 730 FENGHSRIKKYCACAWGIPFVFVVITLSASFDGYGTNtSCWLSVQKGT--IWSFVVPVLLIALANSIILGMVMREILRLNQPATTENfKYQTVRCG 823 888877777788899*************99877654427***988543..45689*******************9999999888887455666666 PP Dicty_CAR 203 fklinyiivfl.vcwvfavvn 222 k ++ +l + w+f v+ FUN_001370-T2 824 AKSATVLLPLLgITWIFGVLT 844 777666665554788888864 PP >> DUF7942 Family of unknown function (DUF7942) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.1 2.4 1.2e+04 13 29 .. 667 683 .. 660 704 .. 0.62 2 ? 10.9 0.6 9.1e-05 0.47 26 99 .. 723 803 .. 706 808 .. 0.66 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 2.4 DUF7942 13 srvYLalvaallvwvlv 29 s + L lvaal++ ++ FUN_001370-T2 667 SVIHLNLVAALAAAQII 683 55666677666655444 PP == domain 2 score: 10.9 bits; conditional E-value: 9.1e-05 DUF7942 26 wvlvdtllvdhedasfagvwplllTaPtsllll.ll.......lpgeeas.gaaalsawlfvlavalgalvnAvllgalaral 99 +v+++ ++ ++ + + + + P++++++ l + ++ + + ++ + w fv+ v+l al+n+++lg+++r + FUN_001370-T2 723 YVMIVRVF-ENGHSRIKKYCACAWGIPFVFVVItLSasfdgygT-NTSCWlSVQKGTIWSFVVPVLLIALANSIILGMVMREI 803 55555555.45555566666667777888776545444443311.233330344556679*******************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (939 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1073 (0.0420043); expected 510.9 (0.02) Passed bias filter: 637 (0.0249364); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.43 # Mc/sec: 8904.99 // Query: FUN_001371-T1 [L=355] Description: FUN_001371 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-40 138.9 11.7 2.9e-40 138.9 11.7 1.5 2 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 5.5 7.4 9.8 1.3 9.4 0.1 2.9 3 RseC_MucC Positive regulator of sigma(E), RseC/MucC Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.16 2.1e+03 134 164 .. 26 53 .. 9 56 .. 0.49 2 ! 138.9 11.7 2.3e-44 2.9e-40 1 259 [. 57 319 .. 57 320 .. 0.83 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.16 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 134 eetvClidfpeeestwevsytlllsvlgfll 164 + C ++ ++ +++ +++ ++v+++ll FUN_001371-T1 26 TTIKCAVENASN---STKALVITAFVVVLLL 53 455555555552...2333333333333333 PP == domain 2 score: 138.9 bits; conditional E-value: 2.3e-44 xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrt..ptnifllnLavaDllvlllvlpfalvyallegdwv...fgevlCklvtaldvvnltasillltaisiDRYlaIvkpl 91 gN l++ v++r+k lr+ p n++++n+a+aD+l + + + ++ l+++ w fge+ Ck+ ++l+++++ asil+++++ +DR+la + + FUN_001371-T1 57 GNSLLVGVVARDKDLRRkfPFNYLIINMAIADILNASSASLVFILFLLIGRLWLsgiFGEITCKISYFLVMFSVAASILTVVVMGLDRFLAAHATM 152 8**************997788*************9974444444444456666522279999********************************99 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx RF 7tm_1 92 kykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeest..wevsytlllsvlgfll.pllvilvcyvrilrtlrksa 184 + + + ++ i+ +W+la +s p l+ +g ++ ++e+ C+ +++++++ + + + ++ v+++++ pl++++++y+ i+ ++r+++ FUN_001371-T1 153 RP---LSTKAVKYAIVSTWLLAGFFSSPYLYRMGIEQG--PNGEYHCVGRWSQNSEEhrHLMKIEEVTKVVVLYIlPLIFMMFFYAIIAFRIRRRS 243 99...457899999*****************8887665..49*********9966665666666666666666666******************99 PP xxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 185 kkekskkkks..arkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPii 259 k +k++s +++++++++++++v++f++cw+P+++ ll+s+ + + l+ + l + lla++n+++NP++ FUN_001371-T1 244 KLPVATKRRSriIQQNQRVVRMIIAIVLIFAVCWFPVHVNHLLRSF-DLSIYCGLPAFLPLSFFLLAHANCAINPWV 319 97666444441157777*****************************.4444555555555788899*********98 PP >> RseC_MucC Positive regulator of sigma(E), RseC/MucC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 0.41 5.3e+03 99 114 .. 42 57 .. 30 73 .. 0.54 2 ? 1.6 2.7 0.025 3.2e+02 58 114 .. 81 137 .. 75 158 .. 0.60 3 ? 9.4 0.1 0.0001 1.3 69 113 .. 216 277 .. 210 290 .. 0.71 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.41 RseC_MucC 99 laalggllglalgfli 114 l++ + +++l+l++l FUN_001371-T1 42 LVITAFVVVLLLSLLG 57 3444444444444443 PP == domain 2 score: 1.6 bits; conditional E-value: 0.025 RseC_MucC 58 evgieeksllkaallvYllPllalilgallgqallkassellaalggllglalgfli 114 +++++ +++l+a+ ++ l++li ++l +++++ ++ +l+++ ++a + + FUN_001371-T1 81 IINMAIADILNASSASLVFILFLLIGRLWLSGIFGEITCKISYFLVMFSVAASILTV 137 566777777788777777778888888888888877555555555444444433322 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0001 RseC_MucC 69 aallvYllPllalilgallgqallk.................assellaalggllglalgfl 113 ++++Y+lPl+++++++++ + +++ ++ ++++++++++ ++ FUN_001371-T1 216 KVVVLYILPLIFMMFFYAIIAFRIRrrsklpvatkrrsriiqQNQRVVRMIIAIVLIFAVCW 277 6789********99998887766555666777777777766666666666666665555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (355 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1277 (0.0499902); expected 510.9 (0.02) Passed bias filter: 507 (0.0198473); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3538.91 // Query: FUN_001372-T1 [L=423] Description: FUN_001372 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-48 163.6 25.4 8.3e-48 163.6 25.4 1.4 2 7tm_1 7 transmembrane receptor (rhodopsin family) 2.3e-06 27.7 25.3 4.1e-06 26.9 25.3 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 1e-05 25.2 32.0 1.3e-05 24.8 32.0 1.1 1 7TM_GPCR_Srh Serpentine type 7TM GPCR chemoreceptor Srh ------ inclusion threshold ------ 0.074 12.9 29.5 0.1 12.4 26.7 2.1 2 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.2 1.7 1.1e+04 149 164 .. 21 36 .. 13 41 .. 0.43 2 ! 163.6 25.4 1.3e-51 8.3e-48 1 260 [] 43 306 .. 43 306 .. 0.93 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 1.7 xxxxxxxxxxxxxxxx RF 7tm_1 149 wevsytlllsvlgfll 164 w+ +++l++vl ++ FUN_001372-T1 21 WTTNMQVLMTVLYSVI 36 3333333333333333 PP == domain 2 score: 163.6 bits; conditional E-value: 1.3e-51 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwv...fgevlCklvtaldvvnltasillltaisiDRYlaIvkplky 93 gN lV++v+++++++r++ n++++n+a+aDll++++v+p ++v +++ +w fg +lCk++ + v+l as+ +l+++++DR+++Iv k+ FUN_001372-T1 43 GNSLVLFVVFKKQNMRSALNLLIVNMAIADLLLTIFVMPYSVVFLFVGLEWFsgiFGLILCKAIFFSLAVSLAASVTSLIVMTVDRFVTIVFVWKR 138 8**************************************************733368999*******************************87666 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 r +v ++v+W+++ +++ p l + ++++ a ++++C++d+ + ++++ ++++++v+ + +pll+++++y+ i+++l++++ ++++ FUN_001372-T1 139 --CLDLRSSKVSLVVIWAISSAIMGPYLQVYTVEQPIAGDDRYFCYPDWTRMPVDFNKLFAVCIFVVLYAIPLLLMAILYSIIVHKLWRNRFARQN 232 ..99*************************9999999888************8889**********************************9998888 PP ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ ++++++++k+l++v ++f++cw+P++i+ + ++ ++++ +l+ ++l++ +l+++ns++NPi+Y FUN_001372-T1 233 sgsgCDATINNSKKRVVKMLITVTCTFAICWFPLHIIHYYIYF-DSQSHMCLSLYVILLSFWLGHANSAINPILY 306 77773444456667**********************9999999.8889999999999*****************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 25.3 6.4e-10 4.1e-06 2 255 .. 38 319 .. 37 321 .. 0.70 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 6.4e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv.llltgtqlkre.....eCFlliivyvfgltaqsvllLvigiDlliavk 91 ++l+GN+l+++++fkk+++rs +++Li+ ++adll+ ++ ++ v +l+ g + + C + + ++l+a+ + l+v+++D+++ + FUN_001372-T1 38 PISLVGNSLVLFVVFKKQNMRSALNLLIVNMAIADLLLTIFVMPYSVvFLFVGLEWFSGifgliLCKAIFFSLAVSLAASVTSLIVMTVDRFVTIV 133 589**************************************999877245544444333111114555555555666777788999******9998 PP 7TM_GPCR_Srsx 92 fPirYr.llskekYllillifpvlyssiilvlgflqrdde....tiivCappla.lagkaseiftlssliinviv.llvylvliiilkkkkek... 177 f + l+++k +++++i + +++ +l+++++++ + ++C p + ++ + ++f++ ++++ ++ ll+ ++l+ i+ +k + FUN_001372-T1 134 FVWKRClDLRSSK-VSLVVIWAISSAIMGPYLQVYTVEQPiagdDRYFCYPDWTrMPVDFNKLFAVCIFVVLYAIpLLLMAILYSIIVHKLWRnrf 228 8776441444444.444444444444444455555554432223889***9876255566688888776654444144445555443333333356 PP 7TM_GPCR_Srsx 178 ............kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilv.llsfsqnffVtywrsseYrkafre 255 ++s k+v k l ++ + f ++Wf i+ ++ ++s l+ + +++ + +++ n + + + ++ +r+af e FUN_001372-T1 229 arqnsgsgcdatINNSKKRVVKMLITVTCTFAICWFPLHIIHYYIYFDSQSHMCLSLYVILLSFWLgHANSAINPILYFIFNKTFRRAFLE 319 6788999***9989999***********************9999988888888888888777765515677789999999********987 PP >> 7TM_GPCR_Srh Serpentine type 7TM GPCR chemoreceptor Srh # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 32.0 2.1e-09 1.3e-05 6 300 .. 25 321 .. 20 323 .. 0.83 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 2.1e-09 7TM_GPCR_Srh 6 lslvlhiitvislPihifgfYcIlfkTPkkMksvkwsLlnlhfwsallDlslsfltipylllPalagy..plGllselgvpteiqvyllvtllalv 99 +++++ ++ + +Pi+++g ++lf kk ++++ L +l + +a+ Dl+l+++++py ++ ++g + G++ + + +++ l ++la+ FUN_001372-T1 25 MQVLMTVLYSVIFPISLVGNSLVLFVVFKK-QNMRSALNLLIVNMAIADLLLTIFVMPYSVVFLFVGLewFSGIFGLI--LCKAIFFSLAVSLAAS 117 567788888999999999999999988777.789999999999****************9998888863367999988..788899********** PP 7TM_GPCR_Srh 100 gvsiillFenRysilvknkkkikwkklrvlylilnyilallfllpiflnip.dqeeaklkvlkklPclpeeffdeepvfvlaldstlllilivlll 194 ++s i++ +R+ ++v k+ ++ ++ l+++ ++ +++ p + +q a + + +P ++ +d +++f +++ ++l++i lll FUN_001372-T1 118 VTSLIVMTVDRFVTIVFVWKRCLDLRSSKVSLVVIWAISSAIMGPYLQVYTvEQPIAGDDRYFCYPDWTRMPVDFNKLFAVCI--FVVLYAIPLLL 211 ****************8867777777777777777777777776665544469********99****9999999889999886..44467777777 PP 7TM_GPCR_Srh 195 lllliqilffvvlliyyllkskksslSkkTrklqkkflialiiQvaipllviliPliyllfsilfgyynqalnnllfiiisl.....hGllstivm 285 + +l +i+++ + + +++ + s +T++ kk ++ ++i v+ + ++ +Pl ++ + i+f++++ ++ l +i++s+ ++++ i+ FUN_001372-T1 212 MAILYSIIVHKLWRNRFARQN-SGSGCDATINNSKKRVVKMLITVTCTFAICWFPLHIIHYYIYFDSQSHMCLSLYVILLSFwlghaNSAINPILY 306 777777777665555444444.46889***************************************************999754444578888999 PP 7TM_GPCR_Srh 286 llvhkpYRkavlsll 300 ++++k +R a+l+ l FUN_001372-T1 307 FIFNKTFRRAFLEAL 321 999****99999876 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.7 0.024 1.5e+02 152 194 .. 14 56 .. 8 63 .. 0.70 2 ? 12.4 26.7 1.6e-05 0.1 17 282 .. 49 322 .. 31 323 .. 0.60 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.024 7TM_GPCR_Srv 152 mpvvadksvierftlialivvvvtciiliiayvllfvvlrkkk 194 m+ ++ +++ l+++++ v++ i+l+ + +lfvv++k++ FUN_001372-T1 14 MASCVQSWTTNMQVLMTVLYSVIFPISLVGNSLVLFVVFKKQN 56 5555555666667777777777888888888888999999665 PP == domain 2 score: 12.4 bits; conditional E-value: 1.6e-05 7TM_GPCR_Srv 17 icllklrkrsktfkttFYklllqhaiaDiitllvyivgavfrklgwieefyfelqeyyaaiyyniayytliirctgivlLslqRllaillPisrlt 112 ++++k ++ +++ l++ aiaD++ ++ + v+ + +e f + ++ ++++ + ++l t+ +++++ R+++i++ +r FUN_001372-T1 49 FVVFKKQN----MRSALNLLIVNMAIADLLLTIFVMPYSVVFLFVGLEWFSGIFGLILCKAIFFSLAVSLAASVTSLIVMTVDRFVTIVFVWKRCL 140 34444433....447777789999****998887666666555555566655566677999999999***********************996655 PP 7TM_GPCR_Srv 113 kivqsaklwkiilvywlvgllislv...........vlkdtdieydneenmpvvadksvierftlialivvvvtciiliiayvllfvvl.rkkk.k 195 + +s+ +v w + i + d + y + ++mpv +k + +++ + + + +++ i+y++++ l r+++ + FUN_001372-T1 141 DLRSSKV---SLVVIWAISSAIMGPylqvytveqpiAGDDRYFCYPDWTRMPVDFNKLFAVCIFVVLYAIP---LLLMAILYSIIVHKLwRNRFaR 230 5444422...2222233322222221111111332122333455666666777777776666665544443...3444555555554331433332 PP 7TM_GPCR_Srv 196 .....kksqtkskslkrevrLaiqvlilvlaqliilifyilklyfsqtlntdpifylRalYpi.lsgllsyinPylllilskdlrkqvlkrlk 282 +t+++s+kr v++ i v+ +++++ l + ++ yf + + y+ l+ l + s inP+l +i++k++r+++l++l FUN_001372-T1 231 qnsgsGCDATINNSKKRVVKMLITVTCTFAICWFPLHIIHYYIYFDSQSHMCLSLYV-ILLSFwLGHANSAINPILYFIFNKTFRRAFLEALH 322 445555556799999999999988777766665555444444444444444445555.33333144567*******************99886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (423 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1550 (0.0606772); expected 510.9 (0.02) Passed bias filter: 579 (0.0226659); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 4366.47 // Query: FUN_001373-T1 [L=129] Description: FUN_001373 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 897 (0.0351145); expected 510.9 (0.02) Passed bias filter: 600 (0.023488); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1310.41 // Query: FUN_001374-T1 [L=209] Description: FUN_001374 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (209 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 923 (0.0361323); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2035.21 // Query: FUN_001375-T1 [L=126] Description: FUN_001375 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-06 26.1 0.0 9.8e-06 25.9 0.0 1.1 1 DEAD DEAD/DEAH box helicase 0.0026 18.2 0.0 0.0029 18.0 0.0 1.1 1 ResIII Type III restriction enzyme, res subunit Domain annotation for each model (and alignments): >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 7.7e-10 9.8e-06 43 129 .. 37 124 .. 22 126 .] 0.75 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 7.7e-10 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxx RF DEAD 43 kegpqalvlaPtreLaeqiveelkkllkk.lglkvasllggdsrkeqlekl..kkadilvgtpgrlldlleerkk.....lknlkllvlDEahrl 129 +++++ v++P+ + +q+v +++k+ + + ++gds+ + k di++g +++l+ +rk+ l++ k+lv+DE+h++ FUN_001375-T1 37 ISKTTVAVVSPLDYIRKQQVASIEKMDCGiSAADIGESIQGDSE------IenGKFDIMIGSAEQWLSDR-WRKAlqfgaLHQTKVLVVDEVHTV 124 567899********************996222333333333333......321459***********966.455567889*************87 PP >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 2.3e-07 0.0029 53 137 .. 39 124 .. 25 126 .] 0.78 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 2.3e-07 ResIII 53 ekkvlflvdrkeLleqakeefkkflseekke.ageilsgdkkkeekkekkivvttiqslskalekekeellk.dkfdviiiDEaHrs 137 + v ++ + + +q +++k+ +++ +ge ++gd++ e + + +i++ + ++ +++ ++ ++ ++ +v+++DE+H + FUN_001375-T1 39 KTTVAVVSPLDYIRKQQVASIEKMDCGISAAdIGESIQGDSEIE-NGKFDIMIGSAEQWLSDRWRKALQFGAlHQTKVLVVDEVHTV 124 34788899999999999998888876655555************.*************9999966666666516667********76 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 576 (0.0225484); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1277.12 // Query: FUN_001376-T1 [L=365] Description: FUN_001376 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.4e-46 157.2 18.8 7.4e-46 157.2 18.8 1.5 2 7tm_1 7 transmembrane receptor (rhodopsin family) 7.5e-07 29.3 15.8 1.2e-06 28.6 15.8 1.3 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 5.5e-06 26.7 14.1 6.2e-06 26.5 13.2 1.5 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 3.8e-05 23.7 15.7 6.5e-05 22.9 15.7 1.3 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv ------ inclusion threshold ------ 0.065 13.2 0.0 0.098 12.6 0.0 1.3 1 VP4_helical Rotavirus VP4 helical domain Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.2 0.63 3.2e+03 133 160 .. 10 35 .. 3 41 .. 0.46 2 ! 157.2 18.8 1.4e-49 7.4e-46 1 260 [] 42 304 .. 42 304 .. 0.89 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 0.63 xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 133 keetvClidfpeeestwevsytlllsvl 160 +++ +C+++ +++++ +t+ ++++ FUN_001376-T1 10 NSSQFCVVHPATSATQ--IGLTVAYFIV 35 5666777777663322..2222222222 PP == domain 2 score: 157.2 bits; conditional E-value: 1.4e-49 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevl...CklvtaldvvnltasillltaisiDRYlaIvkplky 93 gN lVi+v+ r+ klrt+ n++++n+a +D+l +l+++p++++y + + +w g+v+ Ck++ +l ++++ +s+l+lt++++DRYla+v+ +k+ FUN_001376-T1 42 GNSLVIYVVHRHPKLRTTFNMLIVNMAASDILDILTAVPLSVTYLFEGLKWFSGAVGvflCKFLPFLACLSIGSSVLTLTVMTFDRYLAVVHTMKR 137 8*********************************************99999986653444***********************************9 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe...eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakk 186 ++r ++v i ++Wv++ ++ ++l ++ + + ++t C+ + e e++++e+ +++ ++l +++pll ++ +y++i+ ++++++ FUN_001376-T1 138 --PLSPRITTVAITLTWVISGAIFATELHKYTVIN---DFGQTLCVSRWVEdleESHKMEMCEMVFRFLLLYMVPLLAMACLYSKIVLHMWNRRAP 228 ..67***********************99665543...39***********66333448888888999999999*********************9 PP xxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 187 eks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ +++ +r++rk++++l+++v +f++cwlP ++ +l ++ + ++l++ ++ ++ +++n+++NP +Y FUN_001376-T1 229 GEHidkNHQHIERQKRKVVTMLVTIVTLFAICWLPAHVNHFLFTF-NFPLFSCLPTSLIFTLYFWTHANTAINPCLY 304 9885543444445667****************************9.6677888888888889999***********9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 15.8 2.4e-10 1.2e-06 2 255 .. 37 317 .. 36 319 .. 0.71 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 2.4e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv.llltgtqlkree..CFlliivyvfglta..qsvllL.vigiDlliavk 91 ++ l GN+l+i+++ +++kLr+ +++Li+ +++d+l ++ ++ v l++g + + Fl +++ ++ + +svl L v+++D+ +av FUN_001376-T1 37 CLALLGNSLVIYVVHRHPKLRTTFNMLIVNMAASDILDILTAVPLSVtYLFEGLKWFSGAvgVFLCKFLPFLACLSigSSVLTLtVMTFDRYLAVV 132 7889*********************************999988877746777766443321234444444444332224555553789******** PP 7TM_GPCR_Srsx 92 fPirYrllskekYllillifpvlyssiil.vlgflqrddetiivCapplalagkas...eiftlssliinvivllvylvliii............. 170 +++ l ++ + ++i+l+ ++ +++++ + +++++d + C + + + s e+ ++ ++ + ++ + +++ + FUN_001376-T1 133 HTMKRPLSPRITTVAITLTWVISGAIFATeLHKYTVINDFGQTLCVSRWVEDLEEShkmEMCEMVFRFLLLYMVPLLAMACLYskivlhmwnrrap 228 ****99999999**************99934578899999*****998887766552234444444444444444443333333344445555555 PP 7TM_GPCR_Srsx 171 ...lkkkkekkkssskkvlkslkvtvvififgWftstilntvl.lalteseevekliqayagilvllsfsqnffVtywrsseYrkafre 255 + k++++ +++ +kv l + v++f ++W+ + + ++ + ++ + + + + + + + + n +++ ++ +r+ f++ FUN_001376-T1 229 gehIDKNHQHIERQKRKVVTMLVTIVTLFAICWLPAHVNHFLFtFNFPLFSCLPTSLIFTLYFWTHANTAINPCLYLIFNESFREGFKH 317 555555555589999******************98877554441344445555555666677778888888999999999999999986 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 13.2 1.2e-09 6.2e-06 3 247 .. 35 279 .. 33 286 .. 0.75 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 1.2e-09 7TM_GPCR_Srx 3 isliGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsellkellnshliglialgl...YeisplsqllialNRfca 95 + ++ l+ N+lv++++++ ++l++ F++l ++ a s+++ +l+ + + v + + ++++ + ++l++++ +++ s l+ ++++++R +a FUN_001376-T1 35 VFCLALLGNSLVIYVVHRHPKLRTTFNMLIVNMAASDILDILTAVPLSVTYLFEGLKWFSGAVGVFLCKFLPFLAclsIGSSVLTLTVMTFDRYLA 130 55566788********************************************************99998875443100445789999********* PP 7TM_GPCR_Srx 96 vffplkyekifsiknTkiiiviiwivslifit..vlylpegCkllynpetltwsfeeteccktiswyldfllililviitlvlnlltaiklilskk 189 v+ ++ ++ s ++T+++i+++w++s ++ + + + + + w e+ e ++++ ++ l+l ++ l+ ++ ++k++l++ FUN_001376-T1 131 VVHTM--KRPLSPRITTVAITLTWVISGAIFAteLHKYTVINDFGQTLCVSRW-VEDLEESHKMEMCEMVFRFLLLYMVPLLAMACLYSKIVLHMW 223 *9988..6789****************99533243333333333333333444.334555555555543444455555555556666777777777 PP 7TM_GPCR_Srx 190 kskstsseeskrrrkreinffkQsvlQdllflidlvnyfliaplvenkwlqfilttls 247 +++ + e+ ++++ i k +v+ l++++ l+ ++++ v++ +++f + +s FUN_001376-T1 224 NRR-APG-EHIDKNHQHIERQKRKVVTMLVTIVTLFAICWLPAHVNHFLFTFNFPLFS 279 776.333.34577777888889999999999999999999999999999999887776 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 15.7 1.3e-08 6.5e-05 18 280 .. 45 318 .. 25 323 .. 0.69 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.3e-08 7TM_GPCR_Srv 18 cllklrkrsktfkttFYklllqhaiaDiitllvyivgavfrklgwieefyfelqeyyaaiyyniayytliirctgivlLslqRllaillPisrltk 113 ++ + +r+ +++ttF l++ a Di+ +l+ + + v + + ++ f + ++ +++ a ++ + +++++ R+la+++ + ++ FUN_001376-T1 45 LVIYVVHRHPKLRTTFNMLIVNMAASDILDILTAVPLSVTYLFEGLKWFSGAVGVFLCKFLPFLACLSIGSSVLTLTVMTFDRYLAVVHTM---KR 137 44555556666*****************************************************************************888...77 PP 7TM_GPCR_Srv 114 ivqsaklwkiilvywlvgllislvvlkdtdieydneen..mpvvad...ksvierftlialivvvvtc...iiliiayvllfvvlrkkkk...... 195 ++ + +i++ w++ i + l + ++ d ++ +++ ++ +s+ + ++++ ++++ + +++ +y+ +++ + +++ FUN_001376-T1 138 PLSPRITTVAITLTWVISGAIFATELHKYTVINDFGQTlcVSRWVEdleESHKMEMCEMVFRFLLLYMvplLAMACLYSKIVLHMWNRRApgehid 233 888877788888888888877777787777777777776644443301122222333333333333330003333344444444443332666787 PP 7TM_GPCR_Srv 196 kksqtkskslkrevrLaiqvlilvlaql....iilifyilklyfsqtlntdpifylRalYpilsgllsyinPylllilskdlrkqvlkr 280 k++q++++++++ v + + ++ l++++ + +++++ + + l t if+l +++ ++ inP l li+++++r+ + ++ FUN_001376-T1 234 KNHQHIERQKRKVVTMLVTIVTLFAICWlpahVNHFLFTFNFPLFSCLPTSLIFTL-YFWTHAN---TAINPCLYLIFNESFREGFKHQ 318 77878888777777776666666666541221334455666666677888989999.5555555...47*************9988665 PP >> VP4_helical Rotavirus VP4 helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 1.9e-05 0.098 16 81 .. 55 121 .. 48 169 .. 0.83 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.9e-05 VP4_helical 16 elreefnalasevalsdlld.lallpldlssllesvkaiidavkdvaasvmkkfkksglansvstlt 81 +lr fn l ++a sd+ld l+ +pl++ l+e++k av ++ + + ++ +sv tlt FUN_001376-T1 55 KLRTTFNMLIVNMAASDILDiLTAVPLSVTYLFEGLKWFSGAVGVFLCKFLPFLACLSIGSSVLTLT 121 79*****************956789***********9888877666666555555555555666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (365 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1040 (0.0407125); expected 510.9 (0.02) Passed bias filter: 483 (0.0189078); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3674.04 // Query: FUN_001377-T1 [L=430] Description: FUN_001377 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-11 42.9 0.0 1.4e-10 42.0 0.0 1.5 1 DOMON DOMON domain 5e-08 33.8 4.8 1.4e-07 32.3 4.8 1.8 1 Cytochrom_B561 Eukaryotic cytochrome b561 ------ inclusion threshold ------ 0.036 14.1 0.3 0.036 14.1 0.3 1.8 2 DUF2921 Transmembrane E3 ligase/DUF2921 transmembrane 0.049 14.2 0.6 0.049 14.2 0.6 2.1 3 DUF3522 Protein of unknown function (DUF3522) 0.071 13.8 0.4 0.071 13.8 0.4 3.5 2 DUF4064 Protein of unknown function (DUF4064) 0.16 11.9 0.2 0.36 10.8 0.2 1.5 1 ArlX ArlX 0.75 9.8 6.2 1.4 8.9 0.1 2.3 2 GPI2 Phosphatidylinositol N-acetylglucosaminyltran Domain annotation for each model (and alignments): >> DOMON DOMON domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.0 0.0 3.7e-14 1.4e-10 2 119 .. 49 157 .. 48 162 .. 0.75 Alignments for each domain: == domain 1 score: 42.0 bits; conditional E-value: 3.7e-14 DOMON 2 dgeytvsWkvdgdedeiefelsgkvntngwvaiGfsddgkMsnadvvvgwvd.n.grvyvqdyystsgkgaprlddttqditllsaseedgvttlk 95 ++++ ++++ + d++efelsg +w+a+Gfsd++ M+ +d+ +++ + + y d+ +t++++ p++ +i+ + ++d+ ++++ FUN_001377-T1 49 NCDFLITYTAT-NFDTVEFELSGIQ---NWIAVGFSDNELMAETDILMCVSEpSlDGHYYADSRQTPQQTVPTPS-A-VNISARE--FSDNRMKCR 136 899999**999.7788******875...6*********99************65855666666647777744444.5.6777766..9******** PP DOMON 96 frRkldtcdpsqdnkldldstvkl 119 ++R ++++ + n dl+s++ l FUN_001377-T1 137 VSRVINPGLT---NFKDLKSSLFL 157 ****999443...33334555555 PP >> Cytochrom_B561 Eukaryotic cytochrome b561 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.3 4.8 3.8e-11 1.4e-07 2 133 .. 203 334 .. 197 337 .. 0.80 Alignments for each domain: == domain 1 score: 32.3 bits; conditional E-value: 3.8e-11 Cytochrom_B561 2 HpvlmviGfvllmgeailv..yr.vls..lrklskktkklvHlvlqllalilavvgllavfkshneseianlyslHswlGllavvlfllqlvlGf 91 H +lm+++ l+ ++ y +++ + k+++ +vH vl ++ ++l+v+g +++f + + + + H ++G++a++l ++q +++ FUN_001377-T1 203 HGILMTLAWTLFAFVGLFTarYMrQVWqpTKIWGKDAWFTVHRVLMTTTVLLTVTGTILIFVHVE--GWSSGAGAHPICGMIAIILAVIQPIMAA 295 8888888777666666554113222222477778999*********************9988766..89*********************99886 PP Cytochrom_B561 92 vlfllpglskklralllplHvllGlvifvlaivtallGllek 133 + p+++k r ++ H+++G v +v+a+v+++lGl ++ FUN_001377-T1 296 LRPS-PNAPK--RGIFNWSHRIVGTVALVMAVVSIYLGLDQN 334 6555.66666..6666666********************776 PP >> DUF2921 Transmembrane E3 ligase/DUF2921 transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.3 9.8e-06 0.036 76 145 .. 205 281 .. 188 365 .. 0.78 2 ? -2.4 0.1 1.1 4e+03 116 134 .. 404 422 .. 387 428 .. 0.46 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 9.8e-06 DUF2921 76 afataaflkfllffllelRlllliwkarrreaaaegwealrelsvlylrlylyllggllll.yhlsnylk.........l 145 ++t a+ f + l++ R++ ++w+ + + ++ w +vl+++++l+ ++g +l+ +h++ ++ + FUN_001377-T1 205 ILMTLAWTLFAFVGLFTARYMRQVWQPTKIWG-KDAWF--TVHRVLMTTTVLLTVTGTILIfVHVEGWSSgagahpicgM 281 57888999999999*************99998.89999..6888888888888888888887**9988876666654441 PP == domain 2 score: -2.4 bits; conditional E-value: 1.1 DUF2921 116 relsvlylrlylyllggll 134 r ++ +++ l+++ + + + FUN_001377-T1 404 RTMMFVFVILVGFSVSLTI 422 4444444444443333333 PP >> DUF3522 Protein of unknown function (DUF3522) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 1.7 6.3e+03 152 173 .. 199 220 .. 186 235 .. 0.55 2 ? 14.2 0.6 1.4e-05 0.049 100 176 .. 253 335 .. 239 339 .. 0.79 3 ? -3.9 0.3 5.1 1.9e+04 105 125 .. 409 412 .. 398 425 .. 0.46 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1.7 DUF3522 152 qkllpgllllalaliffllgld 173 + l++g+l+ ++ +f+++gl+ FUN_001377-T1 199 KVLAHGILMTLAWTLFAFVGLF 220 4455555444444444444443 PP == domain 2 score: 14.2 bits; conditional E-value: 1.4e-05 DUF3522 100 kylglllvailqekdrwnlantlipilvgllilivvw..llk......clprrrlkklntqkllpgllllalaliffllgldete 176 ++++ +++i+++ + w++ + pi +++i+++v+ ++ + p+ + +n+ + ++g ++l++a++ ++lgld+++ FUN_001377-T1 253 LLTVTGTILIFVHVEGWSSGAGAHPICGMIAIILAVIqpIMAalrpspNAPK--RGIFNWSHRIVGTVALVMAVVSIYLGLDQNQ 335 345566789999999**********887777777777783335668777777..889***********************99976 PP == domain 3 score: -3.9 bits; conditional E-value: 5.1 DUF3522 105 llvailqekdrwnlantlipi 125 + ++i FUN_001377-T1 409 V-----------------FVI 412 1.................111 PP >> DUF4064 Protein of unknown function (DUF4064) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.8 9.7 7 2.6e+04 7 99 .. 205 290 .. 199 329 .. 0.70 2 ? 13.8 0.4 1.9e-05 0.071 8 82 .. 344 429 .. 340 430 .] 0.84 Alignments for each domain: == domain 1 score: -4.8 bits; conditional E-value: 7 DUF4064 7 iLglIGgilgillgllaliflfligsgeasqelte......gaasgedasatlsifstlllvliiialiaiilgivgallvkknkklsGilliiaa 96 iL ++++ l++++gl++ + + +++ +++ ++ t++++l++++ i+i + + g + + G + ii+a FUN_001377-T1 205 ILMTLAWTLFAFVGLFTARY-------------MRqvwqptKIWGKDAWFTVHRVLMTTTVLLTVTGTILIFVHVEGWSSGAGAHPICGMIAIILA 287 44444444444444444433.............332333445665555566667777777788888888888877777777777788888888888 PP DUF4064 97 ils 99 +++ FUN_001377-T1 288 VIQ 290 875 PP == domain 2 score: 13.8 bits; conditional E-value: 1.9e-05 DUF4064 8 LglIGgilgillgllaliflfligsgeasqelte...........gaasgedasatlsifstlllvliiialiaiilgivgallvk 82 ++I++ +g +l++++ ++l+l+++++++ ++t +++++ d+s ++++ t ++v++i ++ l i+++l+ k FUN_001377-T1 344 YAVIAFYIGEFLVFVFEFYLILSKRNKEKRTMTGdipmqssgvetQQQQQPDMSPQEAMIRTMMFVFVILVGFSVSLTIIILLVSK 429 6789999999999999999999999888888888**********888888888888899988888888888888888888887765 PP >> ArlX ArlX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.2 9.8e-05 0.36 8 62 .. 347 403 .. 343 408 .. 0.66 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 9.8e-05 ArlX 8 vsiPlavFfillFrf..vlprlkrlkkqqepeqsqqeqqtqtqqkqqeseeelekdl 62 ++ + F++++F f +l + ++ k++ + + q++ ++tqq+qq ++ e + FUN_001377-T1 347 IAFYIGEFLVFVFEFylILSKRNKEKRTMTGDIPMQSSGVETQQQQQPDMSPQEAMI 403 555666787777776225677777777777778888888999988886555555444 PP >> GPI2 Phosphatidylinositol N-acetylglucosaminyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 1.9 0.03 1.1e+02 187 235 .. 205 274 .. 198 299 .. 0.49 2 ? 8.9 0.1 0.00038 1.4 41 117 .. 310 417 .. 300 422 .. 0.80 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.03 GPI2 187 alllfsielfalfPllrrs............lrkkslkl......hvvltlllvllalllllslsk.........l 235 +l++++ lfa++ l++ + + h vl++++vll++++++ + FUN_001377-T1 205 ILMTLAWTLFAFVGLFTARymrqvwqptkiwG------KdawftvHRVLMTTTVLLTVTGTILIFVhvegwssgaG 274 57888888888888888874444444444331......12222223333333333333333322223344444541 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00038 GPI2 41 dslvivqqlssvvifvlvFvyiyqerlspeslvlvssvltllgylllellksk...............................krkesrlktlks 105 s +iv ++++v+ +v +++++ q++++ l++++++ +g +l+ +++ ++++ + +++ FUN_001377-T1 310 WSHRIVGTVALVMAVVSIYLGLDQNQVDLGKQGLYAVIAFYIGEFLVFVFEFYlilskrnkekrtmtgdipmqssgvetqqqqqPDMSPQEAMIRT 405 5778999*********************99999999999999999887777668888888888999999888888887765554444444566677 PP GPI2 106 aililltllllS 117 +++++++l+++S FUN_001377-T1 406 MMFVFVILVGFS 417 777777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (430 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1065 (0.0416911); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4199.69 // Query: FUN_001378-T1 [L=218] Description: FUN_001378 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-12 46.2 0.0 8.8e-12 45.8 0.0 1.1 1 DOMON DOMON domain Domain annotation for each model (and alignments): >> DOMON DOMON domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.8 0.0 3.4e-16 8.8e-12 2 123 .. 49 161 .. 48 162 .. 0.77 Alignments for each domain: == domain 1 score: 45.8 bits; conditional E-value: 3.4e-16 DOMON 2 dgeytvsWkvdgdedeiefelsgkvntngwvaiGfsddgkMsnadvvvgwvd.n.grvyvqdyystsgkgaprlddttqditllsaseedgvttlk 95 ++++ +++ ++d++efelsg +w+a+Gfsd++ M+ +d+ +++ + + y d+ +t++++ p++ +i+ + ++d+ ++++ FUN_001378-T1 49 NCDFLITYAAT-NSDTVEFELSGI---ENWIAVGFSDNQLMAETDILMCVSEpSlDGHYYADSRQTPQQTVPTPS-A-VNISARE--FSDNRMKCR 136 899999**999.9999******76...46*********99************65855666666647777744444.5.6777766..9******** PP DOMON 96 frRkldtcdpsqdnkldldstvkliwaa 123 ++R ++++ + n dl+s++ l+ a+ FUN_001378-T1 137 VSRVINPGLT---NFKDLNSSLFLLAAY 161 ******9443...333456666666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (218 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 514 (0.0201214); expected 510.9 (0.02) Passed bias filter: 407 (0.0159327); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.42 # Mc/sec: 2114.89 // Query: FUN_001379-T1 [L=86] Description: FUN_001379 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (86 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 458 (0.0179291); expected 510.9 (0.02) Passed bias filter: 227 (0.00888628); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 854.64 // Query: FUN_001380-T1 [L=273] Description: FUN_001380 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-12 47.7 0.0 3.2e-12 47.2 0.0 1.3 1 DOMON DOMON domain Domain annotation for each model (and alignments): >> DOMON DOMON domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.2 0.0 1.3e-16 3.2e-12 1 103 [. 48 144 .. 48 162 .. 0.77 Alignments for each domain: == domain 1 score: 47.2 bits; conditional E-value: 1.3e-16 DOMON 1 edgeytvsWkvdgdedeiefelsgkvntngwvaiGfsddgkMsnadvvvgwvd.n..grvyvqdyystsgkgaprlddttqditllsaseedgvtt 93 e++++ +++++ +d++efelsg +w+a+Gfsd++ M ++d+ +++ d + g+ y++ + t++++ +t ++ l ++e++ ++ FUN_001380-T1 48 ENCDFLITYNTT-SSDTVEFELSGS---GNWIAVGFSDNQLMRDTDILMCVSDaSldGHYYANSRQ-TPQRT----RTTPSAVSILLRAFENNRMK 134 5899********.9999******65...67*********99***********94455555555555.55555....2233456666667******* PP DOMON 94 lkfrRkldtc 103 ++++R ++++ FUN_001380-T1 135 CRVSRVINPG 144 *****99984 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (273 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 515 (0.0201605); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2673.86 // Query: FUN_001381-T1 [L=393] Description: FUN_001381 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-45 156.6 19.8 1.2e-45 156.6 19.8 1.7 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.1e-07 31.9 21.8 2.7e-07 30.7 21.8 1.5 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00018 21.1 24.2 0.00036 20.2 24.2 1.5 1 7TM_GPCR_Srh Serpentine type 7TM GPCR chemoreceptor Srh ------ inclusion threshold ------ 0.088 13.2 1.5 0.21 11.9 1.5 1.6 1 Vma12 Endoplasmic reticulum-based factor for assembly Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.18 1.2e+03 132 159 .. 24 55 .. 10 58 .. 0.59 2 ! 156.6 19.8 1.8e-49 1.2e-45 1 260 [] 59 320 .. 59 320 .. 0.91 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.18 x..xxxxxxxxxxxxxxxx..xxxxxxxxxxx RF 7tm_1 132 e..keetvClidfpeeest..wevsytlllsv 159 + +++ +C+++ p ++++ ++++y+++ +v FUN_001381-T1 24 SvkSDQVSCRLQPPDTATKiaFTAIYAIIGLV 55 2348999*****99954444444444444443 PP == domain 2 score: 156.6 bits; conditional E-value: 1.8e-49 xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtpt.nifllnLavaDllvlllvlpfalvyallegdw...vfgevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+++il+ +k+ r+++ n+f++++a+aD+l +l+++p +++++ + + w v+g++ Ckl+++l ++l as+ +l+ais++RYlaIv+ l+ FUN_001381-T1 59 GNCTIILIAKSKKRIRKVAfNFFIISMAIADILDSLIAVPKMVTSFYIDDLWfggVIGNITCKLLHFLPPLSLAASVSTLAAISVERYLAIVHVLR 154 8****************555**************************998888333468999*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeest..wevsytlllsvlgfll.pllvilvcyvrilrtlrksak 185 +k+++ + +l+ W+l+ l + + l+ +tk+ +++ C+ ++e+ +t + y +++ + f++ p+++++v+y+ i++ lr+++ FUN_001381-T1 155 E--PLSKKKVSFAVLFLWILSSLTVSTSLIKYKTKRI---DGKYLCYGIWSEDLQTnlSILRYEVVAKFALFYViPFCLMIVLYTSIICVLRRRQA 245 *..679************************9999999...89**********66666666777777777777777********************* PP xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 kekskkkksarker.kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ ++k+ ++++ +++k+l++vvv+f+++wlP +i+ l++++ ++ +++ + +ll ++la++n +lNP iY FUN_001381-T1 246 FGENMSQKRIQAQNiTVVKMLVTVVVLFAIVWLPTHIIYLMTAF-DYKTLQCMATPVLLSLVVLAHANGALNPCIY 320 **9988888877778****************************9.77888888889999999************** PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 21.8 4.2e-11 2.7e-07 5 317 .. 51 336 .. 46 338 .. 0.81 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 4.2e-11 7TM_GPCR_Srw 5 ilsivgviinifHliiL.trksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlm 99 i+ +v+++ n+ ++i ++k +r+ + n ++i++ai+Dil l+ + + + ++i+ + ++ ++ +l++l +s +s+ ++ FUN_001381-T1 51 IIGLVALFGNCTIILIAkSKKRIRKVAFNFFIISMAIADILDSLIAVPKMVTSFYIDD----LW-FGGVIGNITCKLLHFLPPLSLAASVSTLAAI 141 6677788888877777547899*****************************8888883....34.444555555556999**************** PP 7TM_GPCR_Srw 100 AliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkiflli 195 + R+l + + l++ lsk k+++ ++++ +l sl + + ++++y+ + + k+ C + ++ +t+ + +l++ ++ FUN_001381-T1 142 SVERYLAIVHVLRE---PLSKKKVSFAVLFLWILSSLTV-STSLIKYKTKRIDGKYL----CYGIWSEDLQTNLS-------------ILRYEVVA 216 *********88887...5889999999888766655555.56788899888887777....96554443444443.............44444444 PP 7TM_GPCR_Srw 196 dgilskiipsillpiltilLiieLrkakksrkklskskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifslllt 291 + l+ +ip l+++l + i Lr+ + +++s+++ ++++ k+ + + + f i+ lp iiy+++++ ++++++ +++ + + +l FUN_001381-T1 217 KFALFYVIPFCLMIVLYTSIICVLRRRQAFGENMSQKRIQAQNITVVKMLVTVVVLFAIVWLPTHIIYLMTAF--DYKTLQCMATPVLLSLVVLAH 310 4555689****************************888777888888999999999999999******99887..4456899999999999***** PP 7TM_GPCR_Srw 292 insisHflicllmSsqYRktvkklfg 317 +n+++ i+l++ +YRk k+l+ FUN_001381-T1 311 ANGALNPCIYLIFNENYRKGLKQLLL 336 **********************9975 PP >> 7TM_GPCR_Srh Serpentine type 7TM GPCR chemoreceptor Srh # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 24.2 5.6e-08 0.00036 16 301 .. 51 336 .. 38 337 .. 0.69 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 5.6e-08 7TM_GPCR_Srh 16 islPihifgfY..cIlfkTPkkMksvkwsLlnlhfwsallDlslsfltipylllPala..gyplGllselgvpteiqvyllvtllalvgvsiillF 107 i + +fg +++ k+ k+ ++v + + +++a+ D++ s++++p ++ +++ + G++ ++ +++ +l ++la+ +++ ++ FUN_001381-T1 51 IIGLVALFGNCtiILIAKSKKRIRKVAFNF--FIISMAIADILDSLIAVPKMVTSFYIddLWFGGVIGNI--TCKLLHFLPPLSLAASVSTLAAIS 142 444455666550045567777776666655..56788999************999887556777888877..89999******************* PP 7TM_GPCR_Srh 108 enRysilvknkkkikwkklrvlylilnyilallfllpiflnipdqeeaklkvlkklPclp..eeffdeepvfvlaldstlllilivllllllliqi 201 +Ry ++v+ ++ +kk + +++ il+ l++ + +++ + +++ k+ c +e ++ +++ +l + + ++l+ ++ ++ + FUN_001381-T1 143 VERYLAIVHVLREPLSKKKVSFAVLFLWILSSLTVSTSLIKYK-----TKRIDGKYLCYGiwSEDLQ-TNLSILRYEV---VAKFALFYVIPFCLM 229 ********99885555555444444555555555445555442.....3333444444320023334.4555555443...355555555555555 PP 7TM_GPCR_Srh 202 lffvvlliyyllkskk..sslSkkTrklqkkflialiiQvaipllviliPliyllfsilfgyyn.qalnn....llfiiislhGllstivmllvhk 290 +++ + +i+ l++++ ++S+k ++ q+ ++ +++ v++ + ++ +P ++ +++ f+y++ q + l++++ +G+l ++ l++++ FUN_001381-T1 230 IVLYTSIICVLRRRQAfgENMSQKRIQAQNITVVKMLVTVVVLFAIVWLPTHIIYLMTAFDYKTlQCMATpvllSLVVLAHANGALNPCIYLIFNE 325 5555555566666655678******************************************9996555432211346677789************* PP 7TM_GPCR_Srh 291 pYRkavlsllk 301 YRk +++ll FUN_001381-T1 326 NYRKGLKQLLL 336 ******99985 PP >> Vma12 Endoplasmic reticulum-based factor for assembly of V-ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 1.5 3.4e-05 0.21 73 121 .. 251 300 .. 239 310 .. 0.80 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.4e-05 Vma12 73 elkevkrqltlilNilvSvvavavaiwiaarssvgl.stpaRvllslfva 121 k ++ q ++++ lv+vv+ ++ +w+ + ++ + + ++ l ++ FUN_001381-T1 251 SQKRIQAQNITVVKMLVTVVVLFAIVWLPTHIIYLMtAFDYKTLQCMATP 300 5799************************9998866567777777777654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (393 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1447 (0.0566451); expected 510.9 (0.02) Passed bias filter: 608 (0.0238011); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 3827.99 // Query: FUN_001381-T2 [L=400] Description: FUN_001381 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-45 156.5 19.8 1.2e-45 156.5 19.8 1.8 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.3e-07 31.8 21.8 2.9e-07 30.6 21.8 1.5 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00018 21.1 24.2 0.00037 20.1 24.2 1.5 1 7TM_GPCR_Srh Serpentine type 7TM GPCR chemoreceptor Srh ------ inclusion threshold ------ 0.089 13.2 1.5 0.22 11.9 1.5 1.6 1 Vma12 Endoplasmic reticulum-based factor for assembly Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.11 7e+02 122 159 .. 23 62 .. 14 65 .. 0.60 2 ! 156.5 19.8 1.9e-49 1.2e-45 1 260 [] 66 327 .. 66 327 .. 0.91 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.11 xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxx RF 7tm_1 122 lfsgtktesaekeetvClidfpeeest..wevsytlllsv 159 + +t t+s ++++ +C+++ p ++++ ++++y+++ +v FUN_001381-T2 23 MNNSTFTVSVKSDQVSCRLQPPDTATKiaFTAIYAIIGLV 62 54555555555999*******9954444444444444443 PP == domain 2 score: 156.5 bits; conditional E-value: 1.9e-49 xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtpt.nifllnLavaDllvlllvlpfalvyallegdw...vfgevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+++il+ +k+ r+++ n+f++++a+aD+l +l+++p +++++ + + w v+g++ Ckl+++l ++l as+ +l+ais++RYlaIv+ l+ FUN_001381-T2 66 GNCTIILIAKSKKRIRKVAfNFFIISMAIADILDSLIAVPKMVTSFYIDDLWfggVIGNITCKLLHFLPPLSLAASVSTLAAISVERYLAIVHVLR 161 8****************555**************************998888333468999*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeest..wevsytlllsvlgfll.pllvilvcyvrilrtlrksak 185 +k+++ + +l+ W+l+ l + + l+ +tk+ +++ C+ ++e+ +t + y +++ + f++ p+++++v+y+ i++ lr+++ FUN_001381-T2 162 E--PLSKKKVSFAVLFLWILSSLTVSTSLIKYKTKRI---DGKYLCYGIWSEDLQTnlSILRYEVVAKFALFYViPFCLMIVLYTSIICVLRRRQA 252 *..679************************9999999...89**********66666666777777777777777********************* PP xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 kekskkkksarker.kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ ++k+ ++++ +++k+l++vvv+f+++wlP +i+ l++++ ++ +++ + +ll ++la++n +lNP iY FUN_001381-T2 253 FGENMSQKRIQAQNiTVVKMLVTVVVLFAIVWLPTHIIYLMTAF-DYKTLQCMATPVLLSLVVLAHANGALNPCIY 327 **9988888877778****************************9.77888888889999999************** PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 21.8 4.5e-11 2.9e-07 5 317 .. 58 343 .. 53 345 .. 0.81 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 4.5e-11 7TM_GPCR_Srw 5 ilsivgviinifHliiL.trksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlm 99 i+ +v+++ n+ ++i ++k +r+ + n ++i++ai+Dil l+ + + + ++i+ + ++ ++ +l++l +s +s+ ++ FUN_001381-T2 58 IIGLVALFGNCTIILIAkSKKRIRKVAFNFFIISMAIADILDSLIAVPKMVTSFYIDD----LW-FGGVIGNITCKLLHFLPPLSLAASVSTLAAI 148 6677788888877777547899*****************************8888883....34.444555555556999**************** PP 7TM_GPCR_Srw 100 AliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkiflli 195 + R+l + + l++ lsk k+++ ++++ +l sl + + ++++y+ + + k+ C + ++ +t+ + +l++ ++ FUN_001381-T2 149 SVERYLAIVHVLRE---PLSKKKVSFAVLFLWILSSLTV-STSLIKYKTKRIDGKYL----CYGIWSEDLQTNLS-------------ILRYEVVA 223 *********88887...5889999999888766655555.56788899888887777....96554443444443.............44444444 PP 7TM_GPCR_Srw 196 dgilskiipsillpiltilLiieLrkakksrkklskskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifslllt 291 + l+ +ip l+++l + i Lr+ + +++s+++ ++++ k+ + + + f i+ lp iiy+++++ ++++++ +++ + + +l FUN_001381-T2 224 KFALFYVIPFCLMIVLYTSIICVLRRRQAFGENMSQKRIQAQNITVVKMLVTVVVLFAIVWLPTHIIYLMTAF--DYKTLQCMATPVLLSLVVLAH 317 4555689****************************888777888888999999999999999******99887..4456899999999999***** PP 7TM_GPCR_Srw 292 insisHflicllmSsqYRktvkklfg 317 +n+++ i+l++ +YRk k+l+ FUN_001381-T2 318 ANGALNPCIYLIFNENYRKGLKQLLL 343 **********************9975 PP >> 7TM_GPCR_Srh Serpentine type 7TM GPCR chemoreceptor Srh # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 24.2 5.8e-08 0.00037 16 301 .. 58 343 .. 45 344 .. 0.69 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 5.8e-08 7TM_GPCR_Srh 16 islPihifgfY..cIlfkTPkkMksvkwsLlnlhfwsallDlslsfltipylllPala..gyplGllselgvpteiqvyllvtllalvgvsiillF 107 i + +fg +++ k+ k+ ++v + + +++a+ D++ s++++p ++ +++ + G++ ++ +++ +l ++la+ +++ ++ FUN_001381-T2 58 IIGLVALFGNCtiILIAKSKKRIRKVAFNF--FIISMAIADILDSLIAVPKMVTSFYIddLWFGGVIGNI--TCKLLHFLPPLSLAASVSTLAAIS 149 444455666550045567777776666655..56788999************999887556777888877..89999******************* PP 7TM_GPCR_Srh 108 enRysilvknkkkikwkklrvlylilnyilallfllpiflnipdqeeaklkvlkklPclp..eeffdeepvfvlaldstlllilivllllllliqi 201 +Ry ++v+ ++ +kk + +++ il+ l++ + +++ + +++ k+ c +e ++ +++ +l + + ++l+ ++ ++ + FUN_001381-T2 150 VERYLAIVHVLREPLSKKKVSFAVLFLWILSSLTVSTSLIKYK-----TKRIDGKYLCYGiwSEDLQ-TNLSILRYEV---VAKFALFYVIPFCLM 236 ********99885555555444444555555555445555442.....3333444444320023334.4555555443...355555555555555 PP 7TM_GPCR_Srh 202 lffvvlliyyllkskk..sslSkkTrklqkkflialiiQvaipllviliPliyllfsilfgyyn.qalnn....llfiiislhGllstivmllvhk 290 +++ + +i+ l++++ ++S+k ++ q+ ++ +++ v++ + ++ +P ++ +++ f+y++ q + l++++ +G+l ++ l++++ FUN_001381-T2 237 IVLYTSIICVLRRRQAfgENMSQKRIQAQNITVVKMLVTVVVLFAIVWLPTHIIYLMTAFDYKTlQCMATpvllSLVVLAHANGALNPCIYLIFNE 332 5555555566666655678******************************************9996555432211346677789************* PP 7TM_GPCR_Srh 291 pYRkavlsllk 301 YRk +++ll FUN_001381-T2 333 NYRKGLKQLLL 343 ******99985 PP >> Vma12 Endoplasmic reticulum-based factor for assembly of V-ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 1.5 3.5e-05 0.22 73 121 .. 258 307 .. 246 317 .. 0.80 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.5e-05 Vma12 73 elkevkrqltlilNilvSvvavavaiwiaarssvgl.stpaRvllslfva 121 k ++ q ++++ lv+vv+ ++ +w+ + ++ + + ++ l ++ FUN_001381-T2 258 SQKRIQAQNITVVKMLVTVVVLFAIVWLPTHIIYLMtAFDYKTLQCMATP 307 5799************************9998866567777777777654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (400 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1475 (0.0577412); expected 510.9 (0.02) Passed bias filter: 640 (0.0250538); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 3871.60 // Query: FUN_001382-T1 [L=93] Description: FUN_001382 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (93 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 448 (0.0175377); expected 510.9 (0.02) Passed bias filter: 331 (0.0129575); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.40s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 944.22 // Query: FUN_001383-T1 [L=485] Description: FUN_001383 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-40 137.8 19.8 1.6e-39 136.4 16.0 2.3 2 7tm_1 7 transmembrane receptor (rhodopsin family) 3.9e-12 46.6 21.2 6.1e-10 39.4 17.9 2.9 3 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 4.6e-09 36.5 15.5 4.6e-09 36.5 15.5 2.0 2 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.0016 18.5 0.0 0.0043 17.1 0.0 1.7 1 Stevor Subtelomeric Variable Open Reading frame ------ inclusion threshold ------ 0.062 14.0 0.0 0.22 12.2 0.0 1.9 1 VERL Vitelline envelope receptor for lysin 0.18 11.7 15.8 0.036 14.0 1.3 3.3 3 DUF3671 Fam-L, Fam-M like protein 5.6 7.1 15.8 0.48 10.6 4.6 2.8 3 FA_desaturase Fatty acid desaturase Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 136.4 16.0 4.5e-43 1.6e-39 1 259 [. 91 354 .. 91 355 .. 0.82 2 ? 2.8 0.1 0.027 98 148 189 .. 436 477 .. 412 485 .] 0.65 Alignments for each domain: == domain 1 score: 136.4 bits; conditional E-value: 4.5e-43 xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrt.ptnifllnLavaDllvlllvlpfalvyallegdw...vfgevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN l+i ++ ++ r+ + n +l+n a aDl+ +++++ ++l+ + eg+w fg++ Ck+v +l vv++++si++lt+i+iDRYlaIv k FUN_001383-T1 91 GNSLIIHIVRTRNDIRKnSFNWLLVNTAAADLVNVVTAFMWSLSFWVNEGYWisgAFGTITCKIVPFLLVVAICVSIWTLTIIAIDRYLAIVCIGK 186 8**********999988577***************54444444444577888222457778*******************************9666 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeest...wevsytlllsvlgfllpllvilvcyvrilrtlrksak 185 + + + i++vW+ a ll + +l+ +t ++ e + ++C+ +++e+e++ + +++ +v+++ +pl++++v+y++i+ l++++ FUN_001383-T1 187 K-P-LSSKSKVRGIIIVWLTAGLLFTSQLYKFKTDEY--EDGLSECYHEWHEDEDKskhIYQAEMIVRVVVTYAVPLFLMFVLYSMIANFLWSHKP 278 6.3.4556666678899***********997777665..59***********88884333333346667778888*******************98 PP xxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 kekskkkksarker...kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPii 259 + +++ ++k++ ++k++++vv++f+lcwlP++i +++++ + +++ t++ ++++la++n+++ P++ FUN_001383-T1 279 PGNVNERAYVKKTKkrrVVIKMMITVVILFALCWLPVHISHIMSAF-YIDAYYTIPVTVKWLFTWLAHANAAIHPWL 354 88775555444443333899*************************9.67788899999999**************98 PP == domain 2 score: 2.8 bits; conditional E-value: 0.027 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 148 twevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 ++ev++t+ ++++++ + ++++l++y++ ++ + k e+ FUN_001383-T1 436 DQEVFLTYGVVLFVLAVFCIILLILYIKLKNRVNNIIKDEAM 477 355666666666666666777778888777777776666554 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.1 0.00065 2.4 111 197 .. 19 108 .. 11 112 .. 0.70 2 ! 39.4 17.9 1.7e-13 6.1e-10 4 281 .. 73 370 .. 71 372 .. 0.69 3 ! 5.9 0.2 0.0028 10 154 187 .. 432 465 .. 422 485 .] 0.68 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.00065 7TM_GPCR_Srv 111 ltkivqsaklwkiilvywlvgllislv.vlkdtdieydneen.mpvvadksvierftlialivvvvtciiliiayvllfvvlrkkk..kkk 197 +++ +++++ + i+ +l g++++++ +d+++ +d e d++v + +t+i+l+ +v+ ++ ++ ++l++ ++r+++ +k+ FUN_001383-T1 19 VRHTIKHNN-FNFIYYCYLLGVILASMdDEIDNSTDFDYEGSgEDDNGDDNVGSGMTTIMLFLYVTILVFALLGNSLIIHIVRTRNdiRKN 108 555555544.44444444666666666555566666666655567788999********************************88833244 PP == domain 2 score: 39.4 bits; conditional E-value: 1.7e-13 7TM_GPCR_Srv 4 lsivtlplYllilic.......llklrkrskt.fkttFYklllqhaiaDiitllvyivgavfrklgwieefyfelqey...yaaiyyniayytlii 88 +++++l lY++il++ ++++ +++++ k F ll+ +a aD++ +++ ++ + w++e y + + +i+ +++++ FUN_001383-T1 73 MTTIMLFLYVTILVFallgnslIIHIVRTRNDiRKNSFNWLLVNTAAADLVNVVTAFMWSLSF---WVNEGYWISGAFgtiTCKIVPFLLVVAICV 165 667777777777664333333344444444444899***************999877655443...466666665544000344444445555666 PP 7TM_GPCR_Srv 89 rctgivlLslqRllaillPisrltkivqsaklwkiilvywl.vgllislvvlkdtdieydneen...mpvvadksvierftlialivvvvt.c... 176 + +++++ R+lai++ +k ++s++++ i++ wl +gll+ + ++k ++ ey++ + d++ + +++ +iv vv+ + FUN_001383-T1 166 SIWTLTIIAIDRYLAIVCIG---KKPLSSKSKVRGIIIVWLtAGLLFTSQLYKFKTDEYEDGLSecyHEWHEDEDKSKHIYQAEMIVRVVVtYavp 258 667888999*******9988...6667777777766666661567777778888888888766668556666666666666665555333212111 PP 7TM_GPCR_Srv 177 .iiliiayvllfvvlrkkkk.....kksqtkskslkrevrLaiqvlilvlaqliilifyilklyfsqtlntdp..ifylRalYpilsgllsyinPy 264 +++ ++y++++ +l + k ++ + +k++kr v +++++++l+ l+ l i ++++ ++ +++++l++ l+ + + i P+ FUN_001383-T1 259 lFLMFVLYSMIANFLWSH-KppgnvNERAYVKKTKKRRVVIKMMITVVILFALCWLPVHISHIMSAFYIDAYYtiPVTVKWLFTWLAHANAAIHPW 353 144556666666666644.1567777777899999999999999999999999999999999999988888764357899**************** PP 7TM_GPCR_Srv 265 lllilskdlrkqvlkrl 281 l + +s++lr qv++ l FUN_001383-T1 354 LFIAFSEKLRVQVMEIL 370 *************9866 PP == domain 3 score: 5.9 bits; conditional E-value: 0.0028 7TM_GPCR_Srv 154 vvadksvierftlialivvvvtciiliiayvllf 187 +++ ++ + ++ ++l+v++v+ciil+i+y+ l FUN_001383-T1 432 RILTDQEVFLTYGVVLFVLAVFCIILLILYIKLK 465 5555566666777888899999999999987664 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 15.5 1.3e-12 4.6e-09 6 316 .. 84 370 .. 79 372 .. 0.76 2 ? -1.8 0.2 0.55 2e+03 200 214 .. 449 463 .. 425 483 .. 0.54 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 1.3e-12 7TM_GPCR_Srw 6 lsivgviinifHl.iiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlmA 100 + +++++ n + + i+ tr +r++s n l++ a +D++++++ ++ + +++ e + + + +++ i+ +l v+ +s+w ++A FUN_001383-T1 84 ILVFALLGNSLIIhIVRTRNDIRKNSFNWLLVNTAAADLVNVVTAFMWSLSFWVNE-----GYWISGAFGTITCKIVPFLLVVAICVSIWTLTIIA 174 45556666655441677*****************************9999555555.....3444555666666667788888889********** PP 7TM_GPCR_Srw 101 liRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifllid 196 + R+l + ++ ++k+ ++ i+iv l+ l+ ++++++++ e+e+ +eC + +++ + +++++ +++ +++ FUN_001383-T1 175 IDRYLAIVCIGKKP----LSSKSKVRGIIIVWLTAGLLFTSQLYKFKTDEYEDGL---SECYH-------EWHE---D---EDKSKHIYQAEMIVR 250 *******9544444....4566667777777777777777777777777666443...47961.......1111...2...234566778888888 PP 7TM_GPCR_Srw 197 gilskiipsillpiltilLiieLrkakksrkklsksk..kneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifslll 290 +++ +p +l+ +l + L+ +k + + k++k++ k+ + + i f + lp i++i+++++ + + +i +++ +f++l FUN_001383-T1 251 VVVTYAVPLFLMFVLYSMIANFLWSHKPPGNVNERAYvkKTKKRRVVIKMMITVVILFALCWLPVHISHIMSAFYID--AYYTIPVTVKWLFTWLA 344 8888888888888887777777777766555444222335779999*****************************98..78*************** PP 7TM_GPCR_Srw 291 tinsisHflicllmSsqYRktvkklf 316 +n+++H +++++S + R v++++ FUN_001383-T1 345 HANAAIHPWLFIAFSEKLRVQVMEIL 370 *****************999999987 PP == domain 2 score: -1.8 bits; conditional E-value: 0.55 7TM_GPCR_Srw 200 skiipsillpiltil 214 + + +i+l il i FUN_001383-T1 449 VLAVFCIILLILYIK 463 122223333333222 PP >> Stevor Subtelomeric Variable Open Reading frame # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.2e-06 0.0043 230 268 .. 437 475 .. 407 478 .. 0.85 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.2e-06 Stevor 230 ssafepygiaalvLlilavvliiLYiWlyrRRknswkhe 268 + +f +yg++ +vL + ++l+iLYi l R n k e FUN_001383-T1 437 QEVFLTYGVVLFVLAVFCIILLILYIKLKNRVNNIIKDE 475 5689***************************99888876 PP >> VERL Vitelline envelope receptor for lysin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 5.9e-05 0.22 33 71 .. 254 292 .. 245 295 .. 0.91 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 5.9e-05 VERL 33 PysvPkndtvvlytvtvrlkWsegtPtylsleCyltksq 71 y+vP vly++ + ++Ws +P ++ y+ k++ FUN_001383-T1 254 TYAVPLFLMFVLYSMIANFLWSHKPPGNVNERAYVKKTK 292 599999999********************9999999875 PP >> DUF3671 Fam-L, Fam-M like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 6.0 0.071 2.6e+02 162 216 .. 79 179 .. 19 187 .. 0.75 2 ? 1.2 0.1 0.084 3.1e+02 145 177 .. 237 267 .. 184 277 .. 0.60 3 ? 14.0 1.3 9.9e-06 0.036 150 213 .. 287 467 .. 227 476 .. 0.76 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.071 DUF3671 162 rialpllflllllllsllldls.....................................................lfgiliylvpfiilgiiiilg 204 ++ +++l ++ ll s + +i+ +vpf++++ i++++ FUN_001383-T1 79 FLYVTIL-VFALLGN------SliihivrtrndirknsfnwllvntaaadlvnvvtafmwslsfwvnegywisgaFGTITCKIVPFLLVVAICVSI 167 2222222.2222222......1334444666777777777888888888888999999999999999*******8777777788999999998888 PP DUF3671 205 iiyilkKvkKYe 216 + +++ + +Y FUN_001383-T1 168 WTLTIIAIDRYL 179 888887777775 PP == domain 2 score: 1.2 bits; conditional E-value: 0.084 DUF3671 145 tisdktlkkiirkkyglrialpllfllllllls 177 s+ +++ + ++++ +a+pl+++++l s FUN_001383-T1 237 DKSKHIYQAEMIVRVVVTYAVPLFLMFVLY--S 267 344445555555555555555555333333..2 PP == domain 3 score: 14.0 bits; conditional E-value: 9.9e-06 DUF3671 150 tlkkiirkkyglrialpllflllllllsllldls.............................................................. 183 kk +++++++++++++++l+ l l++ FUN_001383-T1 287 YVKKTKKRRVVIKMMITVVILFALCWLPVH---Ishimsafyidayytipvtvkwlftwlahanaaihpwlfiafseklrvqvmeilrsiqratrt 379 345555555555555555555444444433...035567778888888888899999999999999999999999999999999************ PP DUF3671 184 .........................................................lfgiliylv.pfiilgiiiilgiiyilkKvk 213 ++l y v +f++ ++ iil i yi K+ FUN_001383-T1 380 rrrsltlnneekestrpqelmrdlwgqeekdlemsskntsapeptaestmfpriltdQEVFLTYGVvLFVLAVFCIILLILYIKLKNR 467 *********************************************************6666666662566666666777777766665 PP >> FA_desaturase Fatty acid desaturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.2 0.011 39 99 167 .. 77 144 .. 49 174 .. 0.53 2 ? 10.6 4.6 0.00013 0.48 96 186 .. 261 347 .. 229 386 .. 0.65 3 ? -3.3 0.3 2.2 8.2e+03 163 171 .. 447 455 .. 428 463 .. 0.46 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.011 FA_desaturase 99 llgllllawllalllllwarrlarrkrpiksrrrrwrllaalllllawlglwlallllagllll.lwllp 167 +l l+++ +++all+ +++ + r+++ i++ + +l++ +++ ++ ++ a+++ ++ ++ +++ FUN_001383-T1 77 MLFLYVTILVFALLGNSLIIHIVRTRNDIRK--NSFNWLLVNTAAADLVNVVTAFMWSLSFWVNeGYWIS 144 3333333344444444444444444443333..3344444444444446666666665554444633333 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00013 FA_desaturase 96 lrlllgllllawllalllllwarrlarrkrpiksrrrrwrllaalllll.awlglwlallllaglllllwllpllvllfllalvfnyleHyg 186 l ++l + +l+++ + + ++++k+ ++r++++ +++ ++ ++++ wl++ + + + +++ ++ ++ +++ ++f++l H+ FUN_001383-T1 261 LMFVLYSMIANFLWSH----KPPGNVNERAYVKKTKKRRVVIKMMITVViLFALCWLPVHISHIMSA-FYIDAYYTIPVTVKWLFTWLAHAN 347 2233333333366666....45555566666666666677777777666033455555555444443.99999999999999999*****86 PP == domain 3 score: -3.3 bits; conditional E-value: 2.2 FA_desaturase 163 lwllpllvl 171 l++l+++ + FUN_001383-T1 447 LFVLAVFCI 455 111111111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (485 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1733 (0.0678411); expected 510.9 (0.02) Passed bias filter: 635 (0.0248581); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4710.04 // Query: FUN_001384-T1 [L=93] Description: FUN_001384 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0079 16.3 0.0 0.0084 16.2 0.0 1.1 1 Stevor Subtelomeric Variable Open Reading frame ------ inclusion threshold ------ 0.029 13.4 0.0 0.032 13.2 0.0 1.0 1 MFS_2 MFS/sugar transport protein 0.032 15.0 0.2 0.039 14.7 0.2 1.1 1 DUF3021 Protein of unknown function (DUF3021) 0.053 13.6 0.5 0.062 13.4 0.5 1.1 1 Tetraspanin Tetraspanin family 0.084 12.9 0.2 0.094 12.7 0.2 1.1 1 DUF6377 Domain of unknown function (DUF6377) 0.11 13.4 0.0 0.14 13.1 0.0 1.1 1 DUF805 Protein of unknown function (DUF805) 0.12 13.0 0.3 0.18 12.5 0.3 1.2 1 LST1 LST-1 protein 0.19 12.3 0.1 0.28 11.7 0.1 1.3 1 NICE-3 NICE-3 protein Domain annotation for each model (and alignments): >> Stevor Subtelomeric Variable Open Reading frame # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 2.6e-06 0.0084 229 260 .. 35 66 .. 13 74 .. 0.84 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.6e-06 Stevor 229 assafepygiaalvLlilavvliiLYiWlyrR 260 + +f ygi ++vL +l vvl+iL+ + + FUN_001384-T1 35 NQETFLMYGIFIFVLAVLCVVLLILFCHVKKQ 66 467899********************988774 PP >> MFS_2 MFS/sugar transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 1e-05 0.032 165 212 .. 33 80 .. 23 88 .. 0.83 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1e-05 MFS_2 165 keerkgylifaligaiLmllgviltalgtkervslrkkekeaqkeals 212 ++++++l++++++ +L++l+v+l+ l+ + ++++r+ +++ +++s FUN_001384-T1 33 MTNQETFLMYGIFIFVLAVLCVVLLILFCHVKKQVRRLNDKMGYGQGS 80 567899**************************9998888777666665 PP >> DUF3021 Protein of unknown function (DUF3021) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.2 1.2e-05 0.039 97 129 .. 39 73 .. 29 74 .. 0.79 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.2e-05 DUF3021 97 llll.tiif.iviYliiwlivylenkkkvkkiNqk 129 +l++ + if +++ ++ li++ ++kk+v+++N+k FUN_001384-T1 39 FLMYgIFIFvLAVLCVVLLILFCHVKKQVRRLNDK 73 334444555599999******************98 PP >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.5 1.9e-05 0.062 74 112 .. 37 70 .. 32 87 .. 0.79 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 1.9e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 74 cllllyfvlllllflaelaagilafvyrdkekeelsnwl 112 l+y +++++l ++++++ il+++++++ + l FUN_001384-T1 37 ETFLMYGIFIFVLAVLCVVLLILFCHVKKQ-----VRRL 70 56789*****************99999999.....2333 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.2 2.9e-05 0.094 69 103 .. 35 72 .. 26 83 .. 0.58 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.9e-05 DUF6377 69 qkrkllillilis...vllllllvllviiykqlkklkk 103 +++++l++ i+i+ vl+++ll+l++ + kq+++l+ FUN_001384-T1 35 NQETFLMYGIFIFvlaVLCVVLLILFCHVKKQVRRLND 72 44555555555550005555555555556666666554 PP >> DUF805 Protein of unknown function (DUF805) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 4.5e-05 0.14 36 73 .. 34 72 .. 25 79 .. 0.68 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 4.5e-05 DUF805 36 gaslsaeavgllllvlillv.slalllpslavtvRRlHD 73 +++ + ++g+++ vl++l+ +l++l +++ +vRRl+D FUN_001384-T1 34 TNQETFLMYGIFIFVLAVLCvVLLILFCHVKKQVRRLND 72 444455556666666666662555667999999*****9 PP >> LST1 LST-1 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.3 5.6e-05 0.18 4 28 .. 48 72 .. 45 84 .. 0.84 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 5.6e-05 LST1 4 lllllvvilsaClCrlhrrvkrler 28 +l +l v+l + +C+++++v+rl+ FUN_001384-T1 48 VLAVLCVVLLILFCHVKKQVRRLND 72 4667889999*************85 PP >> NICE-3 NICE-3 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 8.8e-05 0.28 9 37 .. 46 74 .. 40 90 .. 0.82 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.8e-05 NICE-3 9 vlviavgvlvfillfIfakRqImRfalks 37 ++v+av +v+++lf +k+q+ R++ k FUN_001384-T1 46 IFVLAVLCVVLLILFCHVKKQVRRLNDKM 74 77888888999999999*******99886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (93 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1570 (0.0614602); expected 510.9 (0.02) Passed bias filter: 1065 (0.0416911); expected 510.9 (0.02) Passed Vit filter: 146 (0.0057154); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 899.44 // Query: FUN_001385-T1 [L=523] Description: FUN_001385 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-28 98.8 0.1 2.4e-28 98.1 0.1 1.4 1 SAND SAND domain Domain annotation for each model (and alignments): >> SAND SAND domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.1 0.1 9.5e-33 2.4e-28 4 76 .] 165 237 .. 162 237 .. 0.97 Alignments for each domain: == domain 1 score: 98.1 bits; conditional E-value: 9.5e-33 SAND 4 spvlpVtCgelkgtLykeklkqGisekCIqtedkwltpkeFeieggkekskdWKrsIrcggktLrkliekgil 76 ++vl V+C++ ++ L+k+kl +G ++kCI+++d+w+tp+eFe+++g+++skdWKrsIr+gg+tL++lie+gil FUN_001385-T1 165 TEVLIVRCRNETAELFKNKLGSGGRGKCIKYQDHWMTPSEFEARCGRASSKDWKRSIRYGGRTLQSLIEDGIL 237 68999****************************************************************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (523 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2101 (0.082247); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 5125.03 // Query: FUN_001386-T1 [L=572] Description: FUN_001386 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-124 414.5 29.6 3.4e-123 412.2 29.6 1.9 1 BCCT BCCT, betaine/carnitine/choline family trans 1.2e-09 39.5 0.0 1.2e-09 39.5 0.0 3.3 4 PLAC8 PLAC8 family ------ inclusion threshold ------ 0.18 12.3 2.4 0.48 10.9 2.4 1.7 1 Enterotoxin_HS1 Heat stable E.coli enterotoxin 1 Domain annotation for each model (and alignments): >> BCCT BCCT, betaine/carnitine/choline family transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 412.2 29.6 4e-127 3.4e-123 124 483 .. 1 393 [. 1 395 [. 0.90 Alignments for each domain: == domain 1 score: 412.2 bits; conditional E-value: 4e-127 BCCT 124 laltffhwGlhawaiyalvalalayfayrkglplkissalypllgeriegliGkviDilaviatvfGvatsLGlgvlqinaglself.giensltv 218 ++ltffhwG+h+w +y++v+l +a+++yr+glp++i+s++ypl+g++i+g++G+viD+l++++t+fGv+tsLGlg++q+nag++++ +ie s+t FUN_001386-T1 1 MNLTFFHWGIHGWIVYVVVGLLMAFVCYRQGLPMTIRSCFYPLIGDKIYGWMGDVIDVLSICGTMFGVCTSLGLGAIQLNAGIQRMNsSIEVSSTN 96 789***********************************************************************************9679****** PP BCCT 219 qlliiavitavalisavsGldkGikvlSnlnvllavllllfvlivGptlfilnlfveslgdylqnlvelslrtdaleees.........ewlesWT 305 q++ii+++ta+a++s+++Gl+ Gi++lS++ + + +ll+l+v+++++t+f+lnl+++s+g ylq++++l ++tda+++ + +w+++WT FUN_001386-T1 97 QIIIIWCVTACATVSVITGLKLGIRRLSETCFGIGMLLMLVVFFFDDTWFLLNLYTQSFGYYLQWIIQLGFHTDAFAQMGnsqdkkevvSWMNDWT 192 ***************************************************************************9965566678899******** PP BCCT 306 iFywaWwiawapfvglFiAriSrGRtirefilgvllvptlvtllwftvfGgtalelel...egegelakaaeaeveaalfalleql.......... 388 iFyw+Wwiaw+pfvg+FiA+iSrGRti++fi +++ +p++ +++w+t+fGg+++++e+ + ++++ ++ + ++ ++ l l FUN_001386-T1 193 IFYWGWWIAWSPFVGMFIAKISRGRTIKQFINATMTAPIVYSFMWLTIFGGAGIRMERrafHANITCDSILGGKKSTESLNGLYRLscrskddmwf 288 ******************************************************888743222222222222222222222222223333444455 PP BCCT 389 .......plgtilsvlallliiiffvTsaDSatlvlamlsskgdeepsrllrvfWgvllgavaavlllagg...lealqsasiiaalPfslilllm 474 +gt+ls++ ++ i+++fvTs+DS++lv++ ls++gd +p+ l+rvfW++++ga+a++ll+agg l+alq++si+a++P +++l++m FUN_001386-T1 289 dlveqygDIGTVLSIISIIGIVLYFVTSSDSGSLVIDCLSANGDPDPPILQRVFWAFTEGATATALLYAGGpnaLTALQTVSIAAGVPYTILLCFM 384 55555599**************************************************************999*********************** PP BCCT 475 vvsllkalk 483 +++l++a++ FUN_001386-T1 385 CIALWRAVH 393 ******986 PP >> PLAC8 PLAC8 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 3.7 0.35 3e+03 16 58 .. 62 110 .. 51 171 .. 0.53 2 ? -1.9 0.0 1.1 9.4e+03 27 37 .. 207 218 .. 181 262 .. 0.43 3 ? -4.1 0.1 3 2.6e+04 20 23 .. 382 385 .. 364 393 .. 0.54 4 ! 39.5 0.0 1.4e-13 1.2e-09 12 99 .. 422 528 .. 406 529 .. 0.74 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.35 PLAC8 16 lltlfcpcvlfgrnaerldkg....ntscllalv..lvlllllllllgl 58 + t+f c +g a l+ g n+s+ ++ + ++++++++++ ++ FUN_001386-T1 62 CGTMFGVCTSLGLGAIQLNAGiqrmNSSIEVSSTnqIIIIWCVTACATV 110 3344444444444333333333333222222222222222221222222 PP == domain 2 score: -1.9 bits; conditional E-value: 1.1 PLAC8 27 grnaerldkg.n 37 g +++g + FUN_001386-T1 207 GMFIAKISRGrT 218 333333333321 PP == domain 3 score: -4.1 bits; conditional E-value: 3 PLAC8 20 fcpc 23 ++ c FUN_001386-T1 382 CFMC 385 1122 PP == domain 4 score: 39.5 bits; conditional E-value: 1.4e-13 PLAC8 12 lelclltlfcpcvlfgrnaerldkgntscllalv.....lvllll.................lllllglalilscllRsklRekygiegspceDcl 85 l+ + ++lfcp++ +g++a rld ++s +++ + ++ l ++++l+ +++++ +R+ +Rekygi+g+++eD++ FUN_001386-T1 422 LSRVAVALFCPWYPIGNAAWRLDGSKGSKIAYYLpvaipFY---LwvlgmalepvveglsylAWAILFAFFAYGTATRAGIREKYGINGNMAEDFF 514 455778****************9998887775556654422...12335566777665555433333444448*********************** PP PLAC8 86 vhlcCecCalcQee 99 +++++++ a Q++ FUN_001386-T1 515 AVMLLYPFAAYQMD 528 ************96 PP >> Enterotoxin_HS1 Heat stable E.coli enterotoxin 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 2.4 5.6e-05 0.48 16 24 .. 101 109 .. 93 113 .. 0.89 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 5.6e-05 Enterotoxin_HS1 16 IWCvTACaS 24 IWCvTACa FUN_001386-T1 101 IWCVTACAT 109 9******96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (572 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 823 (0.0322177); expected 510.9 (0.02) Passed bias filter: 384 (0.0150323); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5530.76 // Query: FUN_001387-T1 [L=319] Description: FUN_001387 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.8e-30 104.7 23.6 1e-29 104.3 23.6 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 104.3 23.6 4e-34 1e-29 5 260 .] 42 300 .. 39 300 .. 0.90 Alignments for each domain: == domain 1 score: 104.3 bits; conditional E-value: 4e-34 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 5 VilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtkr 100 V+l+++ ++ lr++++ f+ nLa+ D++++ l++p+++v + + ++ +lC + a +++ as+++l++i DRY +I+ p++ + ++r FUN_001387-T1 42 VLLIYWNKRDLRRVSSKFIANLALIDFVICCLSMPLTIVRLV--SFPSVSPLLCLCHEAASSALRNASFVTLLVICHDRYKSITSPFEP--RLNHR 133 8999999***********************************..677788999************************************..89*** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....... RF 7tm_1 101 ralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks....... 189 a+ +++++W+l + ++p++ ++ + + + C f + + +++ ++ + f++ ++v+l y ri r++ ++ ++ FUN_001387-T1 134 SAKRVLIMAWFLTIPSFVLPFI--EWAKLGK-LRPSACISLFCK---SRQPFFVRFYYFPLFMCGCTVLLPAYLRISRAALSRVHVQALmvrtsvv 223 ********************99..6666643.889999988877...346666666667778888999************9999999777888888 PP .........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .........kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + + ++ke k++k++++vv+ +l+wlPy l++ ++ + ++lv ++ ++l l+y+n+++NP++Y FUN_001387-T1 224 vpactaqrwNPSAIRQKEVKIAKMTGAVVCSICLLWLPYMALTFSVYF---INLSNLVAHLEFVFLALGYFNCVVNPLLY 300 8888888776666667888*****************************...9***************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (319 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 904 (0.0353885); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.34s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 3163.61 // Query: FUN_001388-T1 [L=399] Description: FUN_001388 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-43 146.6 1.5 1e-42 146.4 0.0 1.7 2 RAB3A-like_C Rabin 8-like C-terminal domain 5.9e-10 39.9 12.7 9.9e-10 39.2 12.7 1.3 1 Sec2p GDP/GTP exchange factor Sec2p 0.0012 19.3 7.9 0.002 18.6 7.9 1.3 1 Phage_scaffold Phage capsid assembly scaffolding protein ------ inclusion threshold ------ 0.019 15.9 0.9 10 7.2 0.1 3.0 2 Arg_decarbox_C Arginine decarboxylase C-terminal helical e 0.037 14.0 0.4 0.072 13.1 0.4 1.4 1 DUF1184 Protein of unknown function (DUF1184) 0.038 14.6 13.3 0.11 13.1 13.3 1.7 1 TMF_TATA_bd TATA element modulatory factor 1 TATA bindi 0.041 12.2 11.1 0.058 11.7 11.1 1.1 1 CCDC39 Coiled-coil domain-containing protein 39 0.054 14.0 4.6 0.1 13.1 4.6 1.4 1 Nup54 Nucleoporin complex subunit 54 0.078 13.2 10.9 0.11 12.7 10.9 1.1 1 Laminin_I Laminin Domain I 0.085 12.8 3.2 0.11 12.4 3.2 1.2 1 Exonuc_VII_L Exonuclease VII, large subunit 0.11 13.4 10.1 0.18 12.8 10.1 1.2 1 Fez1 Fez1 0.47 11.0 8.0 0.79 10.2 8.0 1.3 1 UPF0242 Uncharacterised protein family (UPF0242) N- 0.67 10.8 3.6 1.3 9.9 3.6 1.4 1 TcaA_2nd TcaA protein second domain 0.69 10.6 6.9 1.2 9.8 6.4 1.6 2 MTR4_beta-barrel Mtr4-like, beta-barrel domain 0.78 9.9 5.9 1.5 9.0 5.9 1.4 1 DUF7201 Coiled-coil region of unknown function (DUF 0.78 9.5 4.7 1.5 8.6 4.7 1.4 1 DUF4407 Domain of unknown function (DUF4407) 1.8 7.4 6.7 2.5 7.0 6.7 1.1 1 Borrelia_P83 Borrelia P83/100 protein 2.2 9.6 5.7 9 7.6 5.7 1.9 1 Occludin_ELL Occludin homology domain 5.2 7.1 7.4 8.2 6.4 7.4 1.2 1 FapA Flagellar Assembly Protein A beta solenoid 7.2 6.9 10.6 21 5.4 10.2 1.8 2 fvmX5 FtsH ternary system domain X5 Domain annotation for each model (and alignments): >> RAB3A-like_C Rabin 8-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.4 3.5 4.5e+03 8 48 .. 125 165 .. 120 196 .. 0.64 2 ! 146.4 0.0 7.9e-46 1e-42 2 132 .. 267 391 .. 266 395 .. 0.98 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 3.5 RAB3A-like_C 8 fkefkewkenpkldk.sskflkriyrediepclkfsnkelse 48 +e+k+ +e+ kl++ +++ l+r+ +e +e l+ +++l + FUN_001388-T1 125 QEELKKAQEELKLKDeECEKLSRVRNE-LEAELEELTASLFQ 165 567777777777766678888887654.44444444444444 PP == domain 2 score: 146.4 bits; conditional E-value: 7.9e-46 RAB3A-like_C 2 evDpilfkefkewkenpkldksskflkriyrediepclkfsnkelseevleaieentvviEpvsekkltvessspkkcalsevprickyrlklgds 97 evD+ilf+ef++w ++ ++ ++++fl+riy+ed+ cl+f nkel+ +v +aie+nt+++E + k +++kcal++++r c +r+kl+++ FUN_001388-T1 267 EVDVILFREFLQWMDERSVSHDQPFLARIYQEDVLSCLNFPNKELALAVHAAIENNTLMMETFTGKP------VSRKCALTGMSRPCVHRVKLSEK 356 89*************************************************************9988......89********************* PP RAB3A-like_C 98 eewyyiselcrnriaavCdfftylryikqGlvksd 132 +w+++s+ +r ri+avCdf+ty+ryi+qGlvk d FUN_001388-T1 357 GDWHNLSRNSRIRIVAVCDFYTYVRYIQQGLVKAD 391 *********************************86 PP >> Sec2p GDP/GTP exchange factor Sec2p # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.2 12.7 7.8e-13 9.9e-10 33 115 .. 114 192 .. 87 205 .. 0.83 Alignments for each domain: == domain 1 score: 39.2 bits; conditional E-value: 7.8e-13 Sec2p 33 eelkkkevlveksdlekelkklqakleeekkkreeaekekkklekElEdLTasLFeEANkmVaaarrekeavekknekLkeqL 115 ee + + ++ l++elkk q++l+ + ++ e+ + +++le ElE+LTasLF+EA mV +a+ +++a+ek+ ++ ++++ FUN_001388-T1 114 EE----IKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASLFQEAHAMVREAKVKQAAAEKRFKEANNKV 192 33....34458999****************************************************99999999987766554 PP >> Phage_scaffold Phage capsid assembly scaffolding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 7.9 1.6e-06 0.002 27 102 .. 112 188 .. 93 209 .. 0.75 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 1.6e-06 Phage_scaffold 27 kkeyvpkakldklkeekkelkkqlkeadkqleelkkkdneelkkkieelqekn..kkkkaeyeaklaelkldsalkla 102 + e+++ + ++ l+ee+k+++++lk +d++ e+l+ + +el++++eel + + ++ + eak+++++ ++ +k+a FUN_001388-T1 112 SREEIKAQAFERLQEELKKAQEELKLKDEECEKLSRVR-NELEAELEELTASLfqEAHAMVREAKVKQAAAEKRFKEA 188 5678999***************************8885.5*************5433333344444444444444443 PP >> Arg_decarbox_C Arginine decarboxylase C-terminal helical extension # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.1 0.008 10 8 43 .. 92 130 .. 90 134 .. 0.91 2 ? 6.1 0.0 0.017 22 2 28 .. 298 323 .. 298 328 .. 0.91 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.008 Arg_decarbox_C 8 VqydpedLlerlrrqveaa...grLsaeerkalleelea 43 + ++ e+L++++r+++ ++ ++a++ ++l+eel++ FUN_001388-T1 92 CSFSSEELVTTFRQRAPTSpsrEEIKAQAFERLQEELKK 130 689****************99999999999999999985 PP == domain 2 score: 6.1 bits; conditional E-value: 0.017 Arg_decarbox_C 2 aeVLryVqydpedLlerlrrqveaagr 28 ++VL+++++ ++L ++++++e+ FUN_001388-T1 298 EDVLSCLNFPNKELALAVHAAIENN-T 323 79*********************97.5 PP >> DUF1184 Protein of unknown function (DUF1184) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.4 5.7e-05 0.072 136 196 .. 115 175 .. 107 181 .. 0.89 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.7e-05 DUF1184 136 lvktsdfehynqelkkleeklrsakdvseanGfareaiksnilhlwkslfetspvkvinak 196 +k+ fe++++elkk +e+l+ + e r+ +++++ l +slf+++ + v +ak FUN_001388-T1 115 EIKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASLFQEAHAMVREAK 175 578999*********************************************9997666655 PP >> TMF_TATA_bd TATA element modulatory factor 1 TATA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 13.3 8.6e-05 0.11 3 91 .. 110 189 .. 108 209 .. 0.70 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 8.6e-05 TMF_TATA_bd 3 stssagpsvqlverlsseirrlegElaslkeelarleaerdeareEivklmkeneelkelkkeleelekelkeleeryettLellGEKs 91 s s+++ ++q++erl++e+++ + El+ ee+++l++ r+e+++E+ +l+ + + ++ + +++++ + + ++E + FUN_001388-T1 110 SPSREEIKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASLFQEAHAMVREAKVKQAAA---------EKRFKEAN 189 56788899***************************************9999655433333333222222222.........22222333 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 11.1 4.6e-05 0.058 727 808 .. 115 196 .. 105 210 .. 0.84 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 4.6e-05 CCDC39 727 kekreeleeleeeleeleqeleeleekeeelketleekeqeleklekeieeqkeKikRadkqlkklvkeirkkketkselee 808 + k + +e+l+eel++ ++el+ e++e+l++ ++e+e+ele+l+ + ++ + R k + + ++ k+ ++k e+ + FUN_001388-T1 115 EIKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASLFQEAHAMVREAKVKQAAAEKRFKEANNKVEVLQ 196 67889999********************************************999999999988777776666666655333 PP >> Nup54 Nucleoporin complex subunit 54 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 4.6 8.1e-05 0.1 28 105 .. 118 202 .. 107 205 .. 0.85 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 8.1e-05 Nup54 28 vvGFedLkkRlklQeeevaahrerlk.......eineklkelqqkhdletsarieeakrrhtelshRllrllrklevlrnrgyal 105 ++ Fe L++ lk+ +ee+++ e ++ e++ +l+el+ + +e++a ++eak ++++ ++R+ + +k+evl+ al FUN_001388-T1 118 AQAFERLQEELKKAQEELKLKDEECEklsrvrnELEAELEELTASLFQEAHAMVREAKVKQAAAEKRFKEANNKVEVLQGEVTAL 202 677888888887777777777776666666666*********************************************9877776 PP >> Laminin_I Laminin Domain I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 10.9 8.6e-05 0.11 154 238 .. 125 206 .. 96 212 .. 0.69 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 8.6e-05 Laminin_I 154 qkLLsrvqtllqklqeenkaLkealrdsLaeyeakLsDlre.lleeAaaktrdanrlnlanqanlreiekkkeevseeknqleetl 238 q+ L+++q+ l+ ee ++L + +e ea+L+ l + l +eA a +r+a+ +a +++++e+++k+e +++e l+ ++ FUN_001388-T1 125 QEELKKAQEELKLKDEECEKL----SRVRNELEAELEELTAsLFQEAHAMVREAKVKQAAAEKRFKEANNKVEVLQGEVTALKHLV 206 222444444444444444444....4444666899999986256*******************************99988777665 PP >> Exonuc_VII_L Exonuclease VII, large subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 3.2 9e-05 0.11 173 269 .. 102 195 .. 63 229 .. 0.58 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 9e-05 Exonuc_VII_L 173 rlarrlksperlleqqrqrldeleerleralkrkleekrerleelearleraspeerleeakerlealkerlkralkrklekkkerlealaaklea 268 ++++r + ++ e ++q +++l+e+l++ ++++l+ k e++e+l+ r+ r++ e +lee +++l + ++ + r++k k + +++r++++++k+e FUN_001388-T1 102 TFRQRAPTSPSREEIKAQAFERLQEELKK-AQEELKLKDEECEKLS-RV-RNELEAELEELTASLFQEAHAMVREAKVKQAAAEKRFKEANNKVEV 194 44444444444445566666666666666.5556666666666555.33.3334444444444443333333333333333333333333333333 PP Exonuc_VII_L 269 l 269 l FUN_001388-T1 195 L 195 2 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 10.1 0.00014 0.18 62 149 .. 115 203 .. 95 213 .. 0.78 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00014 Fez1 62 esktlelevceneLqrkkneaellrekvgkleeevselreelaelsaee.kelalesdeakaqrqeaeealeslkreverlkaeLkeer 149 e k++ e++++eL+++++e +l +e+ +kl++ +el+ el+el+a+ +e++++ +eak ++++ae++ ++ +++ve l+ e+++ + FUN_001388-T1 115 EIKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASLfQEAHAMVREAKVKQAAAEKRFKEANNKVEVLQGEVTALK 203 55677788888888888888888888888888888888888888776651445578889999999999999999999999999987655 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 8.0 0.00062 0.79 76 160 .. 107 200 .. 81 211 .. 0.62 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00062 UPF0242 76 llteedaedlkileeeleelqseeeeleeelsqkeeeleklkeekeqlklkleqisq...........dfaefkleseeqlkekqlllneyqetie 160 +t++ +i+ ++ e lq+e ++ +eel+ k+ee ekl + +++l+ le+ + + + +e + ke + ++ +q ++ FUN_001388-T1 107 APTSPS--REEIKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTAslfqeahamvrEAKVKQAAAEKRFKEANNKVEVLQGEVT 200 333333..4456777888888888888888888888888888888888877777554444433344434444444455555555555555555554 PP >> TcaA_2nd TcaA protein second domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 3.6 0.001 1.3 12 77 .. 116 181 .. 112 202 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.001 TcaA_2nd 12 ieekDaeklakllsssdssleiseeeveaylkYlkeneselkellssLeeqaeaieeskkkesiet 77 i+ + e l++ l++ +++l+ ++ee e++ + +e e el+el++sL ++a+a+ ++k ++ + FUN_001388-T1 116 IKAQAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASLFQEAHAMVREAKVKQAAA 181 667777999*******************************************99988777666554 PP >> MTR4_beta-barrel Mtr4-like, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 6.4 0.00095 1.2 96 190 .. 94 177 .. 72 191 .. 0.77 2 ? -1.5 0.0 2.8 3.6e+03 150 172 .. 182 202 .. 175 219 .. 0.78 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00095 MTR4_beta-barrel 96 lssIeaisslrlklpkdlrseeareavlkalqe.lkrrfpdgipllDpiedmkikdeefkellrkievlesklesnplhsprleelyalyhek 187 +ss e +++ r + p + ++ee ++++ + lqe lk+ e++k+kdee +l r +++le le+ l+ + ++e a+++e FUN_001388-T1 94 FSSEELVTTFRQRAPTSPSREEIKAQAFERLQEeLKKA----------QEELKLKDEECEKLSRVRNELEAELEE--LTASLFQEAHAMVREA 174 55556677777777777655655555555555535555..........8*************************9..9878888888888776 PP MTR4_beta-barrel 188 kel 190 k FUN_001388-T1 175 KVK 177 544 PP == domain 2 score: -1.5 bits; conditional E-value: 2.8 MTR4_beta-barrel 150 deefkellrkievlesklesnpl 172 ++ fke+ +k+evl+ +++ l FUN_001388-T1 182 EKRFKEANNKVEVLQGEVTA--L 202 56799999999999988877..5 PP >> DUF7201 Coiled-coil region of unknown function (DUF7201) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 5.9 0.0012 1.5 32 112 .. 120 200 .. 113 219 .. 0.77 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0012 DUF7201 32 AieklselsvkvskmLavheEklekseridqlilkeidelrek.mdedhdsvskrisklqkrvsklekrvwiavgalavvvl 112 A e l e +k+ L ++E+ ek+ r+ +++++e++el e h++v + +++q +k k+ ++ v +l + v FUN_001388-T1 120 AFERLQEELKKAQEELKLKDEECEKLSRVRNELEAELEELTASlFQEAHAMVRE-AKVKQAAAEKRFKEANNKVEVLQGEVT 200 678899999999999***************************967777777777.777777777777777776666654443 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 4.7 0.0011 1.5 107 205 .. 114 204 .. 109 229 .. 0.72 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0011 DUF4407 107 keIdqeldeekneeadaakaqlaqalraelaelqaqiaalqaeidaaekeldelqkearcelegtkgtgttgvpGkGpeakekeeeldaaqaelaa 202 +eI+++ e+ +ee ++a+++l+ + ++e ++l + +++l+ae++++++ l ++ ++ +e++ + + +ke++++++ +q e++a FUN_001388-T1 114 EEIKAQAFERLQEELKKAQEELKLK-DEECEKLSRVRNELEAELEELTASLFQEAHAMVREAKVK-------QAAAEKRFKEANNKVEVLQGEVTA 201 5777777777777777777777633.466777777777777777777777777777777776652.......234467889999999999999888 PP DUF4407 203 lqa 205 l+ FUN_001388-T1 202 LKH 204 875 PP >> Borrelia_P83 Borrelia P83/100 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 6.7 0.0019 2.5 214 297 .. 113 201 .. 93 224 .. 0.56 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0019 Borrelia_P83 214 raqvlkkeadkkqkeadkakkkadtaqkaadk...qrkevrqkqqe...aknapepadtsekkedkkvaeekkkeiekaqkeikkkaeea 297 r++ ++ ++ q+e+ ka+++++ ++++ +k r+e + +++e + a + e+k+++ ae++ ke++ + e+ + + +a FUN_001388-T1 113 REEIKAQAFERLQEELKKAQEELKLKDEECEKlsrVRNELEAELEEltaSLFQEAHAMVREAKVKQAAAEKRFKEANN-KVEVLQGEVTA 201 444444555555666666666665555555541112334443333343222334455555666655555555555554.45554444444 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 5.7 0.007 9 17 96 .. 128 206 .. 108 209 .. 0.53 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.007 Occludin_ELL 17 FnaeykeYkeLhaeleavskkfskleeelkslkegskeykkiaeeilqeykklkkdpeylekkkrceyLkekLshiKkli 96 ++ +e k ++e e++s+ ++le+el++l+ + ++ +++ + ++k+ +++++e+ +++e+L+ + + +K+l+ FUN_001388-T1 128 LKKAQEELKLKDEECEKLSRVRNELEAELEELTASLFQEAHAMVR-EAKVKQAAAEKRFKEANNKVEVLQGEVTALKHLV 206 222222222222333333333333444444444443333333333.3556666668899999999999999999999887 PP >> FapA Flagellar Assembly Protein A beta solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 7.4 0.0064 8.2 149 228 .. 119 201 .. 97 217 .. 0.62 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0064 FapA 149 vdepelkekleeleeelkeleeeleklkkklkklpk..ka.ekqldeekkeqleklletkekleeeleeleeelkelkeeles 228 + l+e+l++ +eelk ee+ekl++ ++l++ ++ + +l +e ++++++ ++ e++ +e +++ + l+ e++ FUN_001388-T1 119 QAFERLQEELKKAQEELKLKDEECEKLSRVRNELEAelEElTASLFQEAHAMVREAKVKQAAAEKRFKEANNKVEVLQGEVTA 201 33457888888888888888888888888855554421112444445555555555555555555566666665555555544 PP >> fvmX5 FtsH ternary system domain X5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 10.2 0.017 21 88 158 .. 93 167 .. 80 194 .. 0.65 2 ? 1.9 0.5 0.2 2.5e+02 96 134 .. 162 201 .. 158 205 .. 0.81 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.017 fvmX5 88 nlekkreiray...aendatlrervreqleqeLekkaekeekn..lqaevtraLekklgelrkeldqvvnkvtaea 158 + + ++++ a+ + re+ + q+ ++L+++ +k++++ l+ e ++L + +el el++++ +ea FUN_001388-T1 93 SFSSEELVTTFrqrAP-TSPSREEIKAQAFERLQEELKKAQEElkLKDEECEKLSRVRNELEAELEELTASLFQEA 167 5556666677744222.33457777777777887777766665114566777777777777777777776666555 PP == domain 2 score: 1.9 bits; conditional E-value: 0.2 fvmX5 96 rayaendatlre.rvreqleqeLekkaekeeknlqaevtr 134 + e++a +re +v++++ ++ k+a+++ + lq+evt FUN_001388-T1 162 SLFQEAHAMVREaKVKQAAAEKRFKEANNKVEVLQGEVTA 201 567889999997478888888888999999999****995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (399 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2557 (0.100098); expected 510.9 (0.02) Passed bias filter: 1237 (0.0484243); expected 510.9 (0.02) Passed Vit filter: 181 (0.00708554); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.40u 0.41s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 3839.69 // Query: FUN_001389-T1 [L=111] Description: FUN_001389 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0097 17.4 4.4 0.013 17.0 4.4 1.3 1 Insulin Insulin/IGF/Relaxin family Domain annotation for each model (and alignments): >> Insulin Insulin/IGF/Relaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 4.4 5e-07 0.013 51 81 .] 75 108 .. 25 108 .. 0.69 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 5e-07 Insulin 51 lgaleesr...rkrGiveeCClkpCslkqLesYC 81 l+ + + +++ eeCC ++C+++++++YC FUN_001389-T1 75 LMRGQTVNpetQNTDYHEECCIEGCKVEEIAEYC 108 33332222445777789***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (111 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 771 (0.030182); expected 510.9 (0.02) Passed bias filter: 510 (0.0199648); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1132.43 // Query: FUN_001390-T1 [L=78] Description: FUN_001390 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.031 15.7 3.0 0.064 14.7 3.0 1.5 1 Insulin Insulin/IGF/Relaxin family Domain annotation for each model (and alignments): >> Insulin Insulin/IGF/Relaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 3.0 2.5e-06 0.064 13 81 .] 14 73 .. 7 73 .. 0.54 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.5e-06 Insulin 13 ylvCge.rgffytapkarrevedplveqledgeeaelkqlgaleesr.rkrG.iveeCClkpCslkqLesYC 81 y+ C++ r f a d+ + q + e++ + lg+ ++ + + eeCCl++C+ +++ + C FUN_001390-T1 14 YSACEKkRKRFL-A--------DQNILQSP---EKARSFLGKSTRGYrTNYAlFWEECCLEGCNTEEILEHC 73 555533133333.2........22233333...3333444444333333334267*************9999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (78 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 583 (0.0228225); expected 510.9 (0.02) Passed bias filter: 400 (0.0156586); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 801.07 // Query: FUN_001391-T1 [L=275] Description: FUN_001391 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-12 47.0 41.2 3.4e-12 46.8 41.2 1.0 1 Tropomyosin Tropomyosin 0.00099 19.9 43.8 0.0045 17.8 8.9 3.2 3 DUF4200 Domain of unknown function (DUF4200) 0.0017 18.2 25.3 0.11 12.2 2.8 3.3 3 DUF3450 Protein of unknown function (DUF3450) 0.0047 17.5 28.1 0.054 14.1 2.5 3.2 3 HH_AprE AprE, long alpha-helical hairpin 0.0067 14.8 40.9 0.013 13.9 40.9 1.5 1 CCDC39 Coiled-coil domain-containing protein 39 ------ inclusion threshold ------ 0.011 16.7 3.4 0.011 16.7 3.4 4.1 3 Snapin_Pallidin Snapin/Pallidin 0.016 15.7 18.8 0.63 10.6 2.3 3.1 2 DUF1664 Protein of unknown function (DUF1664) 0.029 15.2 1.9 0.063 14.1 0.5 2.3 2 TopBP1_BRCT0 TopBP1, BRCT0 domain 0.14 12.7 5.7 0.42 11.1 0.4 2.4 2 SLAM Signaling lymphocytic activation molecule (S 0.17 12.5 0.3 1.4 9.6 0.3 2.2 1 MGS MGS-like domain 0.27 11.3 38.5 0.38 10.8 26.2 2.1 2 FKBP15 FK506-binding protein 15-like domain 0.62 10.8 3.9 6.8 7.5 0.4 3.0 2 DUF3718 Protein of unknown function (DUF3718) 0.73 10.3 27.0 1.5 9.3 9.2 3.6 5 Laminin_II Laminin Domain II 0.87 10.5 38.2 0.061 14.2 9.6 3.2 3 APG6_N Apg6 coiled-coil region 1 10.3 33.2 2.1 9.2 19.4 2.4 2 Fez1 Fez1 2.9 8.7 26.5 3.4 8.5 0.3 5.1 6 XhlA Haemolysin XhlA 3.1 8.3 28.3 1.7 9.2 7.0 3.7 3 Nup54 Nucleoporin complex subunit 54 3.3 8.8 5.6 4.8 8.3 0.1 3.0 3 GSH_synthase Eukaryotic glutathione synthase 5.1 7.0 27.3 6.6 6.6 12.3 2.2 2 Exonuc_VII_L Exonuclease VII, large subunit 5.3 7.9 37.3 0.97 10.2 4.4 5.4 6 CCDC-167 Coiled-coil domain-containing protein 167 6.9 7.5 32.9 6 7.7 11.1 3.5 3 Uso1_p115_C Uso1 / p115 like vesicle tethering protein, 9.4 7.2 25.0 2.7 8.9 3.0 3.7 3 OVT1 Major antigen, helical domain Domain annotation for each model (and alignments): >> Tropomyosin Tropomyosin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.8 41.2 2.9e-15 3.4e-12 2 240 .. 31 272 .. 30 274 .. 0.92 Alignments for each domain: == domain 1 score: 46.8 bits; conditional E-value: 2.9e-15 Tropomyosin 2 dkiKeKlqalkleaeeaeeraeeaeeklkeleqeneekeqevasLtrriqllEeelekleerlkeakekleeaekaadeserarKvlEnrelkdde 97 +++++K++ lk+ e+ae+r e+++++l e + + +++e+ +a+L+++ ++E+e+ + rl++ + +l + +++ + +e+a+ l e FUN_001391-T1 31 ENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETLERNENAMAYLSREEDVMIA 126 789*******************************************************************************88888777777777 PP Tropomyosin 98 kleelEaqlkeakeiaeeadrkyeEvarklqlleeeLeeaeeraeaaeskiveLeeelkvvgnnlksLevseekas...eredkyeeklkeltekL 190 + l ++l + k+ + k++E++++++ +e + ae+r e+ + ++L+++l + + +L+ s+ + e e ++++k+k l + FUN_001391-T1 127 TQNALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQSSSRVNTlseEEELAMKKKMKSLRNTF 222 778899999999999999******************99999999999999999999999999999999998765431113334689********** PP Tropomyosin 191 keaelraeeaERkvqkLekerdeleekleeakekykavkeeLdetlaele 240 e e ra ea +k+++L ++++le++l+ ++++ ++eeL ++l+e + FUN_001391-T1 223 MESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKLLNEFN 272 *********************************************99976 PP >> DUF4200 Domain of unknown function (DUF4200) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 8.9 3.8e-06 0.0045 8 108 .. 12 112 .. 5 119 .. 0.92 2 ! 13.8 10.3 6.9e-05 0.08 24 107 .. 112 195 .. 108 196 .. 0.94 3 ? 0.3 10.2 1 1.2e+03 37 102 .. 205 270 .. 196 275 .] 0.84 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 3.8e-06 DUF4200 8 mflvqealdakkeeierleellkereeelekkeqelkedlvkfdkflkeneakreraekkaeeetkekkekekeikklkaeleelkseiskleekl 103 ++v ++l + k+ ++ e+l+++ + l+++ ++ +++ ++f++ l e + + ae +a+ +k+ e+eik+++ l++++ + + + e+l FUN_001391-T1 12 NCDVSRQLTRWKDLKNMATENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETL 107 578889999999999999****************************************************************************** PP DUF4200 104 eeykk 108 e+ + FUN_001391-T1 108 ERNEN 112 99765 PP == domain 2 score: 13.8 bits; conditional E-value: 6.9e-05 DUF4200 24 rleellkereeelekkeqelkedlvkfdkflkeneakreraekkaeeetkekkekekeikklkaeleelkseiskleekleeyk 107 + ++ l+++e+ + + ++ l+++l ++++ + ne+k +a+k++++ + +kk ek ++l + e+l+s+ + +ee++ FUN_001391-T1 112 NAMAYLSREEDVMIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQ 195 56888999****************************************************************999999999887 PP == domain 3 score: 0.3 bits; conditional E-value: 1 DUF4200 37 ekkeqelkedlvkfdkflkeneakreraekkaeeetkekkekekeikklkaeleelkseiskleek 102 e++e +k+++ + + e e++ +a+kk+e+ + +k ++e+e++ + + + ++e skl ++ FUN_001391-T1 205 EEEELAMKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKLLNE 270 567788999999999999999999999999999999999999999998888888888888887666 PP >> DUF3450 Protein of unknown function (DUF3450) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 5.0 0.0017 2 39 87 .. 30 78 .. 13 106 .. 0.66 2 ! 12.2 2.8 9.6e-05 0.11 7 80 .. 124 197 .. 122 210 .. 0.92 3 ! 9.6 1.5 0.00062 0.72 14 70 .. 211 267 .. 207 273 .. 0.91 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0017 DUF3450 39 idklddekqellaeyralkaeleslevynkqlerlvasqeqelasleqq 87 ++l+d+ + l+a++++++a+ e+ + + ++ +++s+e++ a+l++q FUN_001391-T1 30 TENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQ 78 4556666666666666666666666666666666666666666666665 PP == domain 2 score: 12.2 bits; conditional E-value: 9.6e-05 DUF3450 7 lllasgalaatldqvlkeaekavaaaaqsqkkidklddekqellaeyralkaeleslevynkqlerlvasqeqe 80 ++++ +al+++l++++++ + ++ +++k+i++++++k+ +++ ++l + +e+l+ ++ q +++++++ FUN_001391-T1 124 MIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQSS 197 56777788************************************************************999865 PP == domain 3 score: 9.6 bits; conditional E-value: 0.00062 DUF3450 14 laatldqvlkeaekavaaaaqsqkkidklddekqellaeyralkaeleslevynkql 70 +++++++++++ ++ + a ++qkki++l +k++l++e+ + +++++++ ++++l FUN_001391-T1 211 MKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKL 267 57889999*****************************************99988776 PP >> HH_AprE AprE, long alpha-helical hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 6.4 0.00034 0.4 48 106 .. 30 88 .. 14 90 .. 0.88 2 ! 14.1 2.5 4.7e-05 0.054 41 110 .. 109 176 .. 95 179 .. 0.87 3 ? 3.4 5.2 0.087 1e+02 72 164 .. 176 272 .. 171 275 .] 0.68 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00034 HH_AprE 48 aeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelag 106 e +++ +l++ar ++ +++ + ++++++++ +i++++a++aal++q+ e+e+++ FUN_001391-T1 30 TENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKR 88 48889999*********************************************999987 PP == domain 2 score: 14.1 bits; conditional E-value: 4.7e-05 HH_AprE 41 aaadpevaeliaaqrqlfearraalagelailqeqieqleeeieglraqlaalreqlalleeelaglreL 110 ++ +++ + +++++ ++ a ++al+ +l ++++++ e++++++++++++ + q +l+e+ ++l eL FUN_001391-T1 109 RN--ENAMAYLSREEDVMIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYEL 176 33..456689999*************************************************99988777 PP == domain 3 score: 3.4 bits; conditional E-value: 0.087 HH_AprE 72 lqeqieqleeeieglraqlaalreqlalleee.lag...lreLlekGlvpktrllelerelaelegqiaelraeiararqqiaeaelqiaqlraey 163 l+e++ + +i+g+ ++l+++ + l eee la+ +++L + ++ r +e ++++ +l+ + ++l+ e+ + ++ a a++++ +l +e+ FUN_001391-T1 176 LEENLNSKLGQINGYIEELQSSSRVNTLSEEEeLAMkkkMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKLLNEF 271 566666667788888888888888888776542555111445566666677777888888888877777777777777777777777777777777 PP HH_AprE 164 r 164 FUN_001391-T1 272 N 272 5 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 40.9 1.1e-05 0.013 286 521 .. 27 267 .. 15 274 .. 0.90 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.1e-05 CCDC39 286 eeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeik 381 + ++++l++++ +lk +l++++ + en ++++ e + +i++ e+ +l+k+ +++++++++ + ++e ++++ + le +e++ l +e + FUN_001391-T1 27 NMATENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETLERNENAMAYLSREED 122 45678999**************************************************************************************** PP CCDC39 382 klkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkge.....rseeekeelekkieeL 472 + ++ + +l ++k+ + e+++ a+++ik+++ + + e+ ++ el n++ ++ q+ +++l++ seee+ +++kk+++L FUN_001391-T1 123 VMIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQSSsrvntLSEEEELAMKKKMKSL 218 *********************************************************************999987643345788888999****** PP CCDC39 473 eeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqel 521 +++ e ++++ q++i++l + l+++l+ + + +e+l +l FUN_001391-T1 219 RNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKL 267 **99999999999999999999999999999988877777777776655 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 2.2 0.13 1.6e+02 9 47 .. 38 76 .. 23 109 .. 0.50 2 ? 16.7 3.4 9.3e-06 0.011 11 87 .. 82 158 .. 79 160 .. 0.87 3 ? 2.2 4.1 0.32 3.7e+02 30 82 .. 178 233 .. 164 253 .. 0.49 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.13 Snapin_Pallidin 9 ellepklkeldeklkelrqsQeeLleqidrlaeeLqele 47 +ll+ l++ +++ ++ +qs +e++ qid+ + l+ FUN_001391-T1 38 ALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALK 76 345555555555555555555555555555444433333 PP == domain 2 score: 16.7 bits; conditional E-value: 9.3e-06 Snapin_Pallidin 11 lepklkeldeklkelrqsQeeLleqidrlaeeLqeleelqeevlpdlkeya.kKLvnikkrmsslnerlqklqkRaek 87 e ++k++ +l +++ + ++ +e+++r + + l+++++ v++ +++ + +KL+nik+ ++ +++l +++kR++ FUN_001391-T1 82 TEAEIKRISFRLDDVEGQLRMTSETLERNENAMAYLSREED-VMIATQNALnDKLRNIKQTVTCNESKLDEAKKRIKS 158 677899999999999998888899**********9999999.66666665559**********************975 PP == domain 3 score: 2.2 bits; conditional E-value: 0.32 Snapin_Pallidin 30 eeLleqidrlaeeLqeleelqe.evlpdlk..eyakKLvnikkrmsslnerlqklq 82 e+L++++ + + ++el+ ++l++ + + +kK+ ++++ ++ +er ++q FUN_001391-T1 178 ENLNSKLGQINGYIEELQSSSRvNTLSEEEelAMKKKMKSLRNTFMESEERAIEAQ 233 44555555555555544444442112211100223444444444444444444444 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 2.3 0.00055 0.63 45 121 .. 14 90 .. 8 92 .. 0.92 2 ? 9.4 7.5 0.0012 1.4 29 103 .. 121 198 .. 117 257 .. 0.84 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00055 DUF1664 45 svskqleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklkeie 121 +vs+ql++ ++ + + ++L ++++ ++++l++ ++ s++ k+ ++ev+ ++++ + ++k+ e+++k+i+ FUN_001391-T1 14 DVSRQLTRWKDLKNMATENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRIS 90 589999999998899999******************************************99999999999999885 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0012 DUF1664 29 sDlmfvTkrnlsdavesvskqleqvseslaatKkeLsq.ridr..vdkkldeqkeiskeikeevtevredvsnikedv 103 +D+m++T+ l+d + ++ + ++ ++l ++Kk++++ ++++ +k+ + e+ +++++++ +++ ++++++ + FUN_001391-T1 121 EDVMIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSvELQKklAEKRCERLYELEENLNSKLGQINGYIEELQSSS 198 69********************************98763454322356788899999999999999999999998754 PP >> TopBP1_BRCT0 TopBP1, BRCT0 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 4 4.7e+03 63 89 .. 58 84 .. 31 89 .. 0.58 2 ? 14.1 0.5 5.4e-05 0.063 21 64 .. 190 234 .. 173 246 .. 0.78 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 4 TopBP1_BRCT0 63 lkklgcrivsplvvlfclkkqrcvpka 89 l+ + +i s lkkq v a FUN_001391-T1 58 LHEVNVQIDSAEATAAALKKQALVTEA 84 334444444444444555555555555 PP == domain 2 score: 14.1 bits; conditional E-value: 5.4e-05 TopBP1_BRCT0 21 aikelqsekylqtvdeeealelkekdksly.vfdsfssvafshlk 64 i+elqs ++t++eee l +k+k ksl f + + +a++ k FUN_001391-T1 190 YIEELQSSSRVNTLSEEEELAMKKKMKSLRnTFMESEERAIEAQK 234 699*************************94245555555555554 PP >> SLAM Signaling lymphocytic activation molecule (SLAM) protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.4 0.00036 0.42 58 104 .. 136 181 .. 102 189 .. 0.83 2 ? 3.8 0.7 0.065 76 54 95 .. 212 253 .. 189 270 .. 0.67 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00036 SLAM 58 ksihilvtvaespessvkkkivsldlseggspryledgYkfhlenLs 104 + i+ vt +es+ ++ kk+i s++l+++ + + e Y+ + enL+ FUN_001391-T1 136 RNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELE-ENLN 181 568999***********************9999999999975.5665 PP == domain 2 score: 3.8 bits; conditional E-value: 0.065 SLAM 54 ksmnksihilvtvaespessvkkkivsldlseggspryledg 95 k+ ks++ +e + +kki sl+ ++++ r l+ FUN_001391-T1 212 KKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVI 253 3333555555555555556678********999998888754 PP >> MGS MGS-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 0.3 0.0012 1.4 5 50 .. 54 96 .. 51 225 .. 0.79 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0012 MGS 5 lakkleelgfellATgGTakllkeagipvtevvektgegerlggrv 50 + + l+e+++++ + + Ta++lk++ + + ++++++ l+ +v FUN_001391-T1 54 FKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFR--LD-DV 96 6789*******************9988867777777776..44.34 PP >> FKBP15 FK506-binding protein 15-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 7.4 0.019 22 105 183 .. 31 109 .. 14 115 .. 0.62 2 ? 10.8 26.2 0.00032 0.38 39 207 .. 102 272 .. 94 274 .. 0.85 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.019 FKBP15 105 aalqkkeaelqsklssalqesekqkeeleklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekes 183 ++l+ k a l++ l++a+++se+ k+ l+++++q +e++++ lk+q ++ k+++ +l+ +e l + ++ e+ FUN_001391-T1 31 ENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETLER 109 4566666666666777777777777777777777666666666666666666666666666666666555444444444 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00032 FKBP15 39 kiseLleknqryvEqsnlllEqrndslkstaeqsqarvleleqekvklteeLaaataqlse..lqlelaalq.kkeaelqsklssalqesekqkee 131 se le+n++ +l + d++ +t + ++++ ++ q +++L++a++++++ lq++la+ + ++ el+++l+s l + + + ee FUN_001391-T1 102 MTSETLERNEN----AMAYLSREEDVMIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSveLQKKLAEKRcERLYELEENLNSKLGQINGYIEE 193 55666666544....46789999************************************861156666666524567******************* PP FKBP15 132 leklraqveeleekveelkqqlkeeKqkrkeleekltsleeeladlkaekeslekslsd...rkkkaaeerkrleeele 207 l++ + ++ +ee+ +k+++k+ +++ e ee++ + + +++ l +k+sle++l rk a+ee ++l +e++ FUN_001391-T1 194 LQSSSRVNTLSEEEELAMKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVifkRKAWAQEELSKLLNEFN 272 *******************************************************987443277777888899998876 PP >> DUF3718 Protein of unknown function (DUF3718) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.14 1.7e+02 23 38 .. 134 149 .. 129 152 .. 0.89 2 ? 7.5 0.4 0.0058 6.8 13 40 .. 211 248 .. 201 250 .. 0.72 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.14 DUF3718 23 kkrrvysgvkCNgesl 38 k+r++ + v CN++ l FUN_001391-T1 134 KLRNIKQTVTCNESKL 149 789*********9876 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0058 DUF3718 13 Lrkklk..........earikkrrvysgvkCNgesllr 40 ++kk+k e i+ ++ ++++CN +sl r FUN_001391-T1 211 MKKKMKslrntfmeseERAIEAQKKIESLNCNKNSLER 248 44444444444447767789***************976 PP >> Laminin_II Laminin Domain II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 1.9 0.015 17 49 108 .. 18 74 .. 6 76 .. 0.73 2 ? 7.5 5.7 0.0048 5.5 11 90 .. 36 119 .. 25 124 .. 0.73 3 ? 9.3 9.2 0.0013 1.5 4 96 .. 64 157 .. 61 166 .. 0.90 4 ? 8.8 4.4 0.0018 2.1 20 83 .. 129 192 .. 124 206 .. 0.57 5 ? 4.4 2.1 0.042 48 29 74 .. 211 256 .. 197 270 .. 0.85 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.015 Laminin_II 49 dankalrdArrsvkkLeklapqLldklkelkqleeassslsdniseikelIaqARkaAnk 108 +++ ++ + + +L ++ L ++l++ + ++e+ ++++ e+ +I A A+ FUN_001391-T1 18 QLTRWKDLKNMATENLRDKMALLKARLEQAEARSEN---FKQSLHEVNVQIDSAEATAAA 74 555555666667778888888888887777777777...999999999999999887775 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0048 Laminin_II 11 takevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkq.leeasss...lsd 90 +++ ++ l++ +++ en k++l+e+n +++ ++ + +++k+ + + ++k + +++++ +l+ + le ++++ ls+ FUN_001391-T1 36 KMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSEtLERNENAmayLSR 119 444445567788888999999999999999999999999999999999999999999999999998654404444443555665 PP == domain 3 score: 9.3 bits; conditional E-value: 0.0013 Laminin_II 4 laaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.lsdniseik 96 +++a+ ta++ ++q ++++++++ l ++++++ t e ++ +a++ +r+ + + + L dkl+++kq ++s l + ++ik FUN_001391-T1 64 QIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETLERNENAMAYLSREEDVMIATQNALNDKLRNIKQTVTCNESkLDEAKKRIK 157 6899*****************************************99999999999999999***************99887777766666666 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0018 Laminin_II 20 aplsqnlentkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldklkelkqlee 83 ++l+ +l n+k+ + +++++e ++ +k+ + ++A++ L +l ++L +kl +++ e FUN_001391-T1 129 NALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIE 192 4455555566666666666666666666666666666666666666666666666655554433 PP == domain 5 score: 4.4 bits; conditional E-value: 0.042 Laminin_II 29 tkeklseinrsveetnekvkdankalrdArrsvkkLeklapqLldk 74 +k+k+++++++ e +e + +a+k +++ + + Le+++++++++ FUN_001391-T1 211 MKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKR 256 6889999999999999***************************998 PP >> APG6_N Apg6 coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 9.6 5.3e-05 0.061 13 115 .. 39 139 .. 30 146 .. 0.92 2 ? 0.0 12.2 1.3 1.5e+03 32 98 .. 135 199 .. 128 214 .. 0.68 3 ? 3.3 8.6 0.13 1.5e+02 22 90 .. 205 271 .. 201 274 .. 0.76 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 5.3e-05 APG6_N 13 elkkeleeaekerdaYkeflkklekekeseekeeeleelekeleklekeeeelleeLeelekekeeldaelealeeelealdeeeeefwreynelq 108 lk +le+ae +++k+ l++++ + +s+e ++ ++l+k+ +e+e ++ L+++e + + le+ e+ ++ l +ee+ + +n+l+ FUN_001391-T1 39 LLKARLEQAEARSENFKQSLHEVNVQIDSAE--ATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETLERNENAMAYLSREEDVMIATQNALN 132 689***********************99977..899999999999*************************************************99 PP APG6_N 109 lellefq 115 +l + + FUN_001391-T1 133 DKLRNIK 139 8887765 PP == domain 2 score: 0.0 bits; conditional E-value: 1.3 APG6_N 32 lkklekekeseekeeeleelekeleklekeeeelleeLeelekekeeldaelealeeelealdeeee 98 l++++++ + + e++l+e++k+++++e +++ +++ e+l + +e+l+++l +++ e+l++ + FUN_001391-T1 135 LRNIKQTVTCN--ESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQSSSR 199 44455553332..578888888888888888888888888888888888888888887777776655 PP == domain 3 score: 3.3 bits; conditional E-value: 0.13 APG6_N 22 ekerdaYkeflkklekekeseekeeeleelekeleklekeeeelleeLeelekekeeldaelealeeel 90 e+e a k+ +k+l+++ ++ ee e++k++e+l+ ++++l++eL+ + k k+ ++el++l +e FUN_001391-T1 205 EEEELAMKKKMKSLRNTFMES--EERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKLLNEF 271 555556666666666665554..4677889999999999999999999999999999999999987775 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 6.9 0.019 22 79 156 .. 34 111 .. 7 130 .. 0.64 2 ? 9.2 19.4 0.0018 2.1 35 169 .. 130 262 .. 118 272 .. 0.82 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.019 Fez1 79 kneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqa 156 +++ ll+ +++++e+ ++++++l+e++ + ++++++ + k+q +e +++ ++ +++ ++ +L++ ++ e+++ FUN_001391-T1 34 RDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQLRMTSETLERNE 111 445566666666666666667777777666666666666666666666666777777777777777766666555544 PP == domain 2 score: 9.2 bits; conditional E-value: 0.0018 Fez1 35 aLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeea 130 aL +lr+++++++ +e++++e++++++s +l+ + e++ +r + +e+l+ k+g+++ ++el+++ + ++ +e+e +++++ k+ r++ + FUN_001391-T1 130 ALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQSSSRVNTLSEEEELAMKKKMKSLRNT-FME 224 57789*************************************************************99888888777777666666666664.333 PP Fez1 131 leslkreverlkaeLkeerqrkeeqaksFeeERrtWqee 169 e+ e ++ ++L++++++ e++ + R+ W++e FUN_001391-T1 225 SEERAIEAQKKIESLNCNKNSLERELDV-IFKRKAWAQE 262 4444445566777999999998887544.4469999877 PP >> XhlA Haemolysin XhlA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 0.082 95 4 44 .. 42 68 .. 20 75 .. 0.67 2 ? 8.5 0.3 0.0029 3.4 2 48 .. 54 100 .. 53 107 .. 0.94 3 ? 6.0 2.3 0.017 19 13 45 .. 128 160 .. 124 166 .. 0.81 4 ? 6.8 3.7 0.0095 11 2 47 .. 138 179 .. 137 187 .. 0.79 5 ? 3.1 0.2 0.13 1.5e+02 4 37 .. 182 218 .. 179 222 .. 0.76 6 ? 4.2 3.2 0.063 74 9 45 .. 211 247 .. 206 251 .. 0.87 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.082 XhlA 4 eklerietkldnleervdkLeekaaeadekiknlcedlkel 44 r++++e ++++ ++++ +++ ++++ FUN_001391-T1 42 A--------------RLEQAEARSENFKQSLHEVNVQIDSA 68 3..............55555555555556666555555553 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0029 XhlA 2 ikeklerietkldnleervdkLeekaaeadekiknlcedlkeleenq 48 +k+ l +++ ++d+ e + L++ a ++++ik + +l++ e ++ FUN_001391-T1 54 FKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQL 100 899************************************99998875 PP == domain 3 score: 6.0 bits; conditional E-value: 0.017 XhlA 13 ldnleervdkLeekaaeadekiknlcedlkele 45 ++ l++++ +++ + +++k++++ +++k+ e FUN_001391-T1 128 QNALNDKLRNIKQTVTCNESKLDEAKKRIKSVE 160 678888888899999999999999999998876 PP == domain 4 score: 6.8 bits; conditional E-value: 0.0095 XhlA 2 ikeklerietkldnleervdkLeekaaeadekiknlcedlkeleen 47 ik+ ++ e+kld+ ++r++ +e+ + a+++ ce+l eleen FUN_001391-T1 138 IKQTVTCNESKLDEAKKRIKSVELQKKLAEKR----CERLYELEEN 179 89999999**********99998877666655....6666666666 PP == domain 5 score: 3.1 bits; conditional E-value: 0.13 XhlA 4 eklerietkldnlee..rvdkLeekaa.eadekiknl 37 kl++i+ + +l++ rv++L e ++ +++k k+l FUN_001391-T1 182 SKLGQINGYIEELQSssRVNTLSEEEElAMKKKMKSL 218 6899999999999999999999666652567777776 PP == domain 6 score: 4.2 bits; conditional E-value: 0.063 XhlA 9 ietkldnleervdkLeekaaeadekiknlcedlkele 45 +++k ++l ++ + ee+a ea++ki++l+ + ++le FUN_001391-T1 211 MKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLE 247 789999999999999**************98777766 PP >> Nup54 Nucleoporin complex subunit 54 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 8.1 0.053 61 45 131 .. 37 118 .. 17 137 .. 0.54 2 ? 2.5 3.9 0.16 1.9e+02 54 134 .. 130 201 .. 118 203 .. 0.53 3 ? 9.2 7.0 0.0014 1.7 55 116 .. 196 257 .. 167 274 .. 0.79 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.053 Nup54 45 vaahrerlkeineklkelqqkhdletsarieeakrrhtelshRllrllrklevlrnrgyalspeEeelrkkleelekqlndpaqlkg 131 +a++++rl++ + + ++ + + e+ ++i+ a+++ ++l+++ l ++ e+ ++ ++ l++ E +lr e+le++ n+ a + FUN_001391-T1 37 MALLKARLEQAEARSENFK-QSLHEVNVQIDSAEATAAALKKQAL--VTEAEI-KRISFRLDDVEGQLRMTSETLERNENAMAY-LS 118 5555555555555555555.4445555555555555555555543..333333.345555555555555555555555554333.22 PP == domain 2 score: 2.5 bits; conditional E-value: 0.16 Nup54 54 eineklkelqqkhdletsarieeakrrhtelshRllrllrklevlrnrgyalspeEeelrkkleelekqlndpaqlkgrln 134 ++n+kl++++ + + + ++++eak+r + ++ + +++++r l + Ee+l +kl +++ +++ ++ ++r+n FUN_001391-T1 130 ALNDKLRNIK-QTVTCNESKLDEAKKRIK-------SVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQS-SSRVN 201 4555555555.555555555555555432.......222233334445555555666666666666666665444.55555 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0014 Nup54 55 ineklkelqqkhdletsarieeakrrhtelshRllrllrklevlrnrgyalspeEeelrkkl 116 ++++++l+++++l+++ +++ ++++ +e ++R ++ +k+e l+ + +l+ e + + k+ FUN_001391-T1 196 SSSRVNTLSEEEELAMKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRK 257 245788889***************************************99998877666654 PP >> GSH_synthase Eukaryotic glutathione synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.2 0.63 7.3e+02 21 36 .. 77 92 .. 27 128 .. 0.54 2 ? 0.5 0.2 1.1 1.3e+03 10 54 .. 121 165 .. 112 179 .. 0.70 3 ? 8.3 0.1 0.0041 4.8 21 79 .. 206 264 .. 195 273 .. 0.87 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.63 GSH_synthase 21 eyellekhgikvirlt 36 +++l ++ +ik i + FUN_001391-T1 77 KQALVTEAEIKRISFR 92 2223333333333333 PP == domain 2 score: 0.5 bits; conditional E-value: 1.1 GSH_synthase 10 nernvfDqrlleyellekh.gikvirltleelleetkleesekkkL 54 ++ ++ q +l+ +l++ + ++++ +l+e ++++k + +kkL FUN_001391-T1 121 EDVMIATQNALNDKLRNIKqTVTCNESKLDEAKKRIKS-VELQKKL 165 55567778889999988554888888899999988865.2233444 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0041 GSH_synthase 21 eyellekhgikvirltleelleetkleesekkkLlvkkpsktqevavvYfRagYepedy 79 e el+ k+++k++r t+ e +e++ ++++ ++L ++k+s ++e v++ R++++ e+ FUN_001391-T1 206 EEELAMKKKMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEEL 264 78999999***********99999656788999****999***********99998876 PP >> Exonuc_VII_L Exonuclease VII, large subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 15.1 0.013 15 146 275 .. 19 165 .. 8 167 .. 0.56 2 ? 6.6 12.3 0.0057 6.6 146 271 .. 124 241 .. 113 274 .. 0.49 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.013 Exonuc_VII_L 146 lerleelekrleralkrrlerkrqrlerlarrlksperlleqqrqrldeleerleralkrk..............leekrerleelearleraspe 227 l r ++l++ +++l+ +++ + rle++++r ++ ++ l++ + ++d++e+ + lk++ l++ + +l+++++ ler++++ FUN_001391-T1 19 LTRWKDLKNMATENLRDKMALLKARLEQAEARSENFKQSLHEVNVQIDSAEATAAA-LKKQalvteaeikrisfrLDDVEGQLRMTSETLERNENA 113 56667777777777787787777777777777777777777777777776655555.555534444443333333333333333333333332222 PP Exonuc_VII_L 228 erleeakerl.....ealkerlkralkrklekkkerlealaaklealsplavL 275 + +++e++ +al+++l r++k++++ ++++l+++++++++++ ++ L FUN_001391-T1 114 MAYLSREEDVmiatqNALNDKL-RNIKQTVTCNESKLDEAKKRIKSVELQKKL 165 2222222222333323333344.467778888999999999999998888776 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0057 Exonuc_VII_L 146 lerleelekrleralkrrlerkrqrlerlarrlksperlleqqrqrldeleerleralkrkleekrerleelearleraspeerleeakerlealk 241 + +++ ++ r++k++++ ++++l+++++r+ks e + + +++r+++l +le++l++kl + + +eel+ ++s+ ++l+e++ +l+ + FUN_001391-T1 124 MIATQNALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLY-ELEENLNSKLGQINGYIEELQ----SSSRVNTLSEEE-ELAMK- 212 334444444445566777777777888888777554444444444444432.233333334444444444444....222222222222.22211. PP Exonuc_VII_L 242 erlkralkrklekkkerlealaaklealsp 271 ++ ++l++++ +++er ++++k+e+l+ FUN_001391-T1 213 KK-MKSLRNTFMESEERAIEAQKKIESLNC 241 22.233444455555555555566666554 PP >> CCDC-167 Coiled-coil domain-containing protein 167 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 4.5 5.2e+03 56 69 .. 23 36 .. 11 42 .. 0.75 2 ? 6.1 4.1 0.016 18 6 60 .. 44 102 .. 39 131 .. 0.66 3 ? 10.2 4.4 0.00084 0.97 9 61 .. 82 152 .. 74 156 .. 0.91 4 ? 7.8 3.5 0.0047 5.4 3 58 .. 139 194 .. 137 195 .. 0.83 5 ? 7.1 4.0 0.0077 8.9 8 56 .. 179 227 .. 174 229 .. 0.90 6 ? 3.6 2.3 0.1 1.2e+02 23 64 .. 230 270 .. 226 273 .. 0.81 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 4.5 CCDC-167 56 keLkkLrkENrKsm 69 k+Lk++ EN + FUN_001391-T1 23 KDLKNMATENLRDK 36 67888888887654 PP == domain 2 score: 6.1 bits; conditional E-value: 0.016 CCDC-167 6 Idkleeklasckerlervekklrkeelseed..RkeL..ekeleelkekleknekeLkk 60 +++ e + +++k++l +v+ ++ ++e + + +++L e e + ++ +l++ e +L++ FUN_001391-T1 44 LEQAEARSENFKQSLHEVNVQIDSAEATAAAlkKQALvtEAEIKRISFRLDDVEGQLRM 102 67889999999999999999999998887766644442233334455555555555543 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00084 CCDC-167 9 leeklasckerlervekklrkeelseed..................RkeLekeleelkekleknekeLkkL 61 +e +++++ rl++ve +lr ++ + e+ +++L++ l+++k+ ++ ne++L + FUN_001391-T1 82 TEAEIKRISFRLDDVEGQLRMTSETLERnenamaylsreedvmiatQNALNDKLRNIKQTVTCNESKLDEA 152 7999***************998888877889*************************************875 PP == domain 4 score: 7.8 bits; conditional E-value: 0.0047 CCDC-167 3 akeIdkleeklasckerlervekklrkeelseedRkeLekeleelkekleknekeL 58 + +++ e kl + k+r+++ve + + +e e+ eLe+ l++ +++ + +eL FUN_001391-T1 139 KQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEEL 194 6788999*********************9999999999988887666666666665 PP == domain 5 score: 7.1 bits; conditional E-value: 0.0077 CCDC-167 8 kleeklasckerlervekklrkeelseedRkeLekeleelkekleknek 56 +l+ kl +++ +e+++ + r ++lsee+ +++k +++l++ + e+ FUN_001391-T1 179 NLNSKLGQINGYIEELQSSSRVNTLSEEEELAMKKKMKSLRNTFMESEE 227 678899999999****************************999887775 PP == domain 6 score: 3.6 bits; conditional E-value: 0.1 CCDC-167 23 vekklrkeelseedRkeLekeleelkekleknekeLkkLrkE 64 +e + + e+l+ + +++Le+el+ + ++ ++eL+kL E FUN_001391-T1 230 IEAQKKIESLNCN-KNSLERELDVIFKRKAWAQEELSKLLNE 270 5666666666555.99*********************99665 PP >> Uso1_p115_C Uso1 / p115 like vesicle tethering protein, C terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 11.3 0.28 3.2e+02 8 69 .. 42 107 .. 23 151 .. 0.62 2 ? 3.8 4.0 0.08 93 5 47 .. 130 169 .. 126 179 .. 0.64 3 ? 7.7 11.1 0.0051 6 3 79 .. 163 239 .. 161 269 .. 0.92 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.28 Uso1_p115_C 8 seasslkdeaeelkaeLqelkkqaesleqk....eseakeleaevkkleeelkklkaeleeekeke 69 ++++++ e+ k++L e + q+ s+e +++a +eae+k++ l++++ +l++ e+ FUN_001391-T1 42 ARLEQAEARSENFKQSLHEVNVQIDSAEATaaalKKQALVTEAEIKRISFRLDDVEGQLRMTSETL 107 333344444444444444444444444444555555577777777777777777777777666554 PP == domain 2 score: 3.8 bits; conditional E-value: 0.08 Uso1_p115_C 5 eleseasslkdeaeelkaeLqelkkqaesleqkeseakeleae 47 l ++ ++k+ ++ +++L+e+kk+++s e + k +e++ FUN_001391-T1 130 ALNDKLRNIKQTVTCNESKLDEAKKRIKSVELQ---KKLAEKR 169 566677778888888888888888888888777...3333333 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0051 Uso1_p115_C 3 kseleseasslkdeaeelkaeLqelkkqaesleqkeseakeleaevkkleeelkklkaeleeekekekekqsEldDL 79 k+ +e++ + l ++ e+l+++L + + +e+l++++ + e+e ++++ +k l++ e +e + e+q+ +++L FUN_001391-T1 163 KKLAEKRCERLYELEENLNSKLGQINGYIEELQSSSRVNTLSEEEELAMKKKMKSLRNTFMESEERAIEAQKKIESL 239 5667999999*************************999999999999***********9999999999998888876 PP >> OVT1 Major antigen, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 3.0 0.0023 2.7 28 86 .. 41 99 .. 19 113 .. 0.81 2 ? 4.2 5.0 0.067 78 1 66 [. 133 198 .. 133 214 .. 0.87 3 ? 4.9 1.7 0.042 48 2 61 .. 214 273 .. 213 275 .] 0.84 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0023 OVT1 28 eelkrkllkdlenqrarldavtseldklqteyesatkntvaieqtvkElkqqrDeiskq 86 + + +++ en +++l v+ ++d+++++ +++k++ ++e+++k + + D+++ q FUN_001391-T1 41 KARLEQAEARSENFKQSLHEVNVQIDSAEATAAALKKQALVTEAEIKRISFRLDDVEGQ 99 44445556667999999********************************9999998776 PP == domain 2 score: 4.2 bits; conditional E-value: 0.067 OVT1 1 dkyrdlEneYnsllrkleekdaalknleelkrkllkdlenqrarldavtseldklqteyesatknt 66 dk+r++ + + kl+e + +k++e +k+ + k e+ + + ++s l +++ e+++ ++ FUN_001391-T1 133 DKLRNIKQTVTCNESKLDEAKKRIKSVELQKKLAEKRCERLYELEENLNSKLGQINGYIEELQSSS 198 799999999999999************************************999998887766554 PP == domain 3 score: 4.9 bits; conditional E-value: 0.042 OVT1 2 kyrdlEneYnsllrkleekdaalknleelkrkllkdlenqrarldavtseldklqteyes 61 k+++l n + + + e ++++++l+ k++l ++l+ +r ++el+kl +e+++ FUN_001391-T1 214 KMKSLRNTFMESEERAIEAQKKIESLNCNKNSLERELDVIFKRKAWAQEELSKLLNEFNA 273 6667777777666666678899********************************999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (275 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2918 (0.11423); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 50 (0.00195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 22 [number of targets reported over threshold] # CPU time: 0.46u 0.41s 00:00:00.87 Elapsed: 00:00:00.42 # Mc/sec: 2615.04 // Query: FUN_001392-T1 [L=307] Description: FUN_001392 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-84 282.2 9.5 4.6e-84 281.9 9.5 1.1 1 ApeC C-terminal domain of apextrin Domain annotation for each model (and alignments): >> ApeC C-terminal domain of apextrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 281.9 9.5 1.8e-88 4.6e-84 1 208 [] 25 232 .. 25 232 .. 0.99 Alignments for each domain: == domain 1 score: 281.9 bits; conditional E-value: 1.8e-88 ApeC 1 WPaGsYGlPkpvsgCpesegveWktGvrfqdtedddekskksaslhlagsvskegvkqefCikkdtkgeeerpeWpeGkYCiykkgdeCPagleeG 96 WP G+YG+P+p +gCp++ ++eWktG++++dtedd++ +++s+++h+ ++s++g++q+fC+k ++g++ + WpeGkYC+ykkg +CP+gl++G FUN_001392-T1 25 WPGGTYGMPMPDTGCPSDGSTEWKTGWTYHDTEDDNNDNQRSNIFHMPVNFSAHGIQQKFCLKVGNNGNTGSEIWPEGKYCLYKKG-VCPSGLKQG 119 **************************************************************************************.5******** PP ApeC 97 yirwdDensevdnenkesGtlPeGvYde.ntliefCCstkGskdtaikLPldspfyLlayesasCqkvkgakvteeflkfddedeenkdaeggahP 191 +irwdDe+se+d ++k+ G+lP+G+Y+ +t+i++CCstkG+ +++i+LP+ +pfyLl+y+sa+Cqkv g+kvt+ef+kfdd+d++n+da+gg+hP FUN_001392-T1 120 FIRWDDEQSEIDYKDKHFGDLPDGNYEIsHTTINYCCSTKGNINNPIQLPALKPFYLLTYDSAQCQKVAGTKVTSEFIKFDDDDQANTDAAGGEHP 215 ***************************88******************************************************************* PP ApeC 192 ylvtkkkkdltlyyCyY 208 y+ ++++ +l++yyCyY FUN_001392-T1 216 YGPSEDPFNLKIYYCYY 232 ****************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (307 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 687 (0.0268937); expected 510.9 (0.02) Passed bias filter: 537 (0.0210217); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3034.77 // Query: FUN_001393-T1 [L=274] Description: FUN_001393 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-09 38.5 4.8 2.3e-09 37.4 4.8 1.6 1 KIAA0319_N Dyslexia-associated protein KIAA0319 N-terminal d Domain annotation for each model (and alignments): >> KIAA0319_N Dyslexia-associated protein KIAA0319 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.4 4.8 9.2e-14 2.3e-09 3 83 .. 41 124 .. 39 126 .. 0.86 Alignments for each domain: == domain 1 score: 37.4 bits; conditional E-value: 9.2e-14 KIAA0319_N 3 kCqegkvlfgaglrseeet.hlqllegshsvqsCqaaCCqspsCdafWlleemCilvnCskpesCeakrt..dssksllvflkr 83 +C++g+v++++++ +++ + l + + ++ C CC+ + C+a+ l ++ C+ v+C + ++C ++ ++ + ++ f+kr FUN_001393-T1 41 SCEPGAVQHNVTFLHGTKSgSFTKLGKVSDLEVCMLLCCELERCQAAFLAGNYCYSVTCFTTNHCATAPAlnNKWQPMVAFVKR 124 7*********99888655427999999**************************************9765411567888999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (274 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 844 (0.0330397); expected 510.9 (0.02) Passed bias filter: 518 (0.0202779); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2705.12 // Query: FUN_001394-T1 [L=653] Description: FUN_001394 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-18 67.2 0.3 4.3e-18 66.0 0.3 1.6 1 BTB BTB/POZ domain 2.8e-14 53.9 0.5 3.4e-08 34.4 0.2 2.3 2 Ank_2 Ankyrin repeats (3 copies) 9.7e-13 48.1 0.5 0.00058 20.5 0.0 3.6 3 Ank Ankyrin repeat 9.2e-10 39.0 2.2 2.7e-05 24.8 1.0 3.7 3 Ank_4 Ankyrin repeats (many copies) 1.2e-06 29.0 0.6 3e-06 27.7 0.6 1.7 1 BACK BTB And C-terminal Kelch 1.8e-05 25.5 0.1 0.026 15.4 0.0 2.6 2 Ank_5 Ankyrin repeats (many copies) 0.00016 22.3 0.2 3.6 9.0 0.0 3.6 3 Ank_3 Ankyrin repeat ------ inclusion threshold ------ 0.018 16.1 0.0 0.045 14.8 0.0 1.6 1 PHR PHR domain Domain annotation for each model (and alignments): >> BTB BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.0 0.3 1.4e-21 4.3e-18 6 108 .. 228 335 .. 224 337 .. 0.93 Alignments for each domain: == domain 1 score: 66.0 bits; conditional E-value: 1.4e-21 BTB 6 ekgklcDvtlvved.......gkkfkahkavLaacSpyFkalfsskeeeessvseieledvspedfealLefiYtgeleiseenveelLaladklq 94 + ++Dv ++v+d + +++ahk vLa +Sp+F a+f + +e+s +iel+d+++e + ++L+++Y +el+i++ +v +++la+k+ FUN_001394-T1 228 LNPMMSDVSFLVQDstnkesvKVSLPAHKYVLAISSPVFFAMFHGV-VAEQSR-QIELPDCDSECLTEFLRYVYYDELQITANSVLGVMYLAKKYL 321 566799**********99999999**********************.677774.5***************************************** PP BTB 95 ipslvkkceeflkk 108 + l++ c +fl++ FUN_001394-T1 322 VLPLIRRCGQFLEE 335 ***********987 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.0 3.7e-09 1.2e-05 33 88 .. 7 64 .. 6 66 .. 0.93 2 ! 34.4 0.2 1.1e-11 3.4e-08 6 68 .. 48 111 .. 47 116 .. 0.88 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 3.7e-09 Ank_2 33 LhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadina 88 L +Aa +g ++vk Ll++g+ v+ + +g +L +Aa + + +iv+ Ll++gadina FUN_001394-T1 7 LTIAAAAGDWKAVKDLLDQGVCVDscSPEGFRPLCIAAFWAYNNIVQQLLDRGADINA 64 67899999999*********889997799***************************96 PP == domain 2 score: 34.4 bits; conditional E-value: 1.1e-11 Ank_2 6 kngnlelvklLl.egadanlqdk.ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAa 68 +n+ +v++Ll gad+n ++ +++taLh+A +gh +++ L+eh+ d+ dn grta +A+ FUN_001394-T1 48 YNN---IVQQLLdRGADINACNRgTNWTALHCATFQGHGKVIMTLMEHNPDLTirDNLGRTAVDFAS 111 556...*************8887899**********************76655779******99886 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0051 16 7 31 .. 8 32 .. 7 34 .. 0.85 2 ! 20.5 0.0 1.8e-07 0.00058 2 33 .] 36 67 .. 35 67 .. 0.86 3 ! 17.5 0.1 1.7e-06 0.0055 2 33 .] 70 101 .. 69 101 .. 0.94 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0051 Ank 7 HlAaraghlevvklLLkhGAdvnar 31 +Aa ag+ + vk LL++G+ v+ + FUN_001394-T1 8 TIAAAAGDWKAVKDLLDQGVCVDSC 32 578889**********88*999865 PP == domain 2 score: 20.5 bits; conditional E-value: 1.8e-07 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G+ PL +Aa + + ++v+ LL++GAd+na+++ FUN_001394-T1 36 GFRPLCIAAFWAYNNIVQQLLDRGADINACNR 67 777******667777******88******995 PP == domain 3 score: 17.5 bits; conditional E-value: 1.7e-06 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 +T+LH+A gh +v+ L +h+ d+ +rd+ FUN_001394-T1 70 NWTALHCATFQGHGKVIMTLMEHNPDLTIRDN 101 69*******99**********999*****997 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.0 0.0053 17 1 41 [. 7 47 .. 7 53 .. 0.85 2 ! 24.8 1.0 8.4e-09 2.7e-05 2 46 .. 41 86 .. 40 86 .. 0.88 3 ! 8.3 0.0 0.0013 4.2 12 38 .. 85 111 .. 82 112 .. 0.92 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0053 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasng 41 l+ Aa++g+ +++k Ll+ g+ ++ + ++ g+ +L +Aa++ FUN_001394-T1 7 LTIAAAAGDWKAVKDLLDQGVCVDSCsPE-GFRPLCIAAFWA 47 57899****************99999675.999999999765 PP == domain 2 score: 24.8 bits; conditional E-value: 8.4e-09 Ank_4 2 haAaksghlellklLlengadinat.dgngetaLhfAasngnlevl 46 + Aa + +++ Ll+ gadina+ g +taLh+A + g+ +v+ FUN_001394-T1 41 CIAAFWAYNNIVQQLLDRGADINACnRGTNWTALHCATFQGHGKVI 86 67888888889999***********778899***********8875 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0013 Ank_4 12 llklLlengadinatdgngetaLhfAa 38 ++ +L e+ +d+ +d+ g+ta++fA+ FUN_001394-T1 85 VIMTLMEHNPDLTIRDNLGRTAVDFAS 111 7899*********************97 PP >> BACK BTB And C-terminal Kelch # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.7 0.6 9.3e-10 3e-06 4 77 .. 345 417 .. 342 451 .. 0.88 Alignments for each domain: == domain 1 score: 27.7 bits; conditional E-value: 9.3e-10 BACK 4 ilefAeaysceeLkeaakefilknfeevlkseeFleLskeqllellssdeLnvesEeevfeavlkWlkhdveer 77 l A ++ eeL+++++ +++ n ++ l+s+ FleL+ +++l++++ L +E e+f+ ++ W +h+ +++ FUN_001394-T1 345 TLTRARQFREEELEKRCWFIVDLNTKQCLESSSFLELDCAVIKSLMRRETL-RIEEGELFKHCMLWAEHQCKKE 417 5678999********************************************.6689**************9864 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 8e-06 0.026 15 54 .. 35 75 .. 22 77 .. 0.90 2 ! 7.6 0.0 0.0024 7.6 33 56 .] 86 110 .. 82 110 .. 0.87 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 8e-06 Ank_5 15 egytpLhvAakygaleivrlLlangvdlnlkdeeg.ltpld 54 eg+ pL++Aa +++iv+ Ll++g+d+n+++ +t+l+ FUN_001394-T1 35 EGFRPLCIAAFWAYNNIVQQLLDRGADINACNRGTnWTALH 75 6789***********************************98 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0024 Ank_5 33 rlLl.angvdlnlkdeegltpldlA 56 ++ l +++ dl+++d+ g t++d+A FUN_001394-T1 86 IMTLmEHNPDLTIRDNLGRTAVDFA 110 5566688****************98 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.63 2e+03 6 26 .. 7 26 .. 7 28 .. 0.88 2 ! 9.0 0.0 0.0011 3.6 2 31 .] 36 64 .. 35 64 .. 0.88 3 ! 8.2 0.0 0.0021 6.6 2 29 .. 70 96 .. 69 98 .. 0.89 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.63 Ank_3 6 LhlAarngrleivklLleklg 26 L +Aa g+ ++vk Ll+ +g FUN_001394-T1 7 LTIAAAAGDWKAVKDLLD-QG 26 679**************9.66 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0011 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g pL +Aa + iv+ Ll+ +gadina FUN_001394-T1 36 GFRPLCIAAFWAYNNIVQQLLD-RGADINA 64 667888999999999*******.*****96 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0021 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 ++t+Lh+A g+ +++ L e +++d+ FUN_001394-T1 70 NWTALHCATFQGHGKVIMTLME-HNPDL 96 79*************9999999.88887 PP >> PHR PHR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 1.4e-05 0.045 20 129 .. 518 634 .. 509 640 .. 0.76 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.4e-05 PHR 20 irFsvdr..diflvGvglYgssgesa...eyevkielietekeeksekvlaendtefvsdg....sskvaevlfkepveieanvkytasaklk.gp 105 ++F++ + ++++G l+ + + + + + k++l k+e+++kv++ ++ e++ d+ s + ++++f+ ++ ++++v+y ++ ++ ++ FUN_001394-T1 518 LSFTAISesPVYIAGARLFTRTLGLTdadNRQDKVQL--WIKDESQDKVIGFTEGEYSPDNsgaySGDGIDIKFNTAILVRNGVRYSLRCVISfSQ 611 5666543358999999999999885544455555666..445678888888888888877777778899*******************99999644 PP PHR 106 s.syyGtkGlrevtveegkvtfqFs 129 s +++ + +++v ++++f+F+ FUN_001394-T1 612 SvTSNRNTPQKDVVF--DQTKFTFE 634 458899999999999..88999996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (653 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 774 (0.0302995); expected 510.9 (0.02) Passed bias filter: 680 (0.0266197); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6456.68 // Query: FUN_001395-T1 [L=321] Description: FUN_001395 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-98 328.6 0.8 5.2e-98 328.4 0.8 1.0 1 TAL_FSA Transaldolase/Fructose-6-phosphate aldolase Domain annotation for each model (and alignments): >> TAL_FSA Transaldolase/Fructose-6-phosphate aldolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 328.4 0.8 2e-102 5.2e-98 1 285 [] 14 315 .. 14 315 .. 0.95 Alignments for each domain: == domain 1 score: 328.4 bits; conditional E-value: 2e-102 TAL_FSA 1 ivlDtadleaikklieeggikgvTtNPslikkaie...ysalydeaiaeikkkg....kkveeayekLavedirealdllgedgrvslEVdarlsd 89 +v+D++d++ i+++++ +++TtNPsl+++a + y++l+++a++ k++g ++v+ea++kL+v ++ e+l+++ +grvs+EVdarls+ FUN_001395-T1 14 VVADSGDFKVIEQYKP----TDATTNPSLLLAASKmpeYKHLLEKAVQHGKSTGstleEQVTEAMDKLFVLFGLEILKII--PGRVSTEVDARLSF 103 689*************....************9988888889999999998888**************************..************** PP TAL_FSA 90 dteatieeArrLialve.....rknvlIKiPateeGikAikeLeaeGinvnvTliFslaqalaaaeagasviSpFvgRiddlg.kkleekealkgk 179 d+e++ie+A+++i+ +e ++++lIK+ +t+eGi+A+k Le+eGi++n+Tl+F +aqa+a+aeag+++iSpFvgRi d++ k+ ++ke++ ++ FUN_001395-T1 104 DVEGSIEKAKKFIKSYEeagisKERILIKLSSTWEGIEAAKVLEKEGIHCNMTLLFAFAQAVACAEAGVTLISPFVGRIFDWYvKNTDQKEYQPKD 199 ***********************************************************************************9999999****** PP TAL_FSA 180 ddgvalvkeiyeiykkygysTkvlaasfrnveqvealagcdtvTippdllealakhgkt.......sekl..eeaek..lleklfrlgidedavae 264 d+gv++v++iy++ykk++y+T v++asfrn+ q+++lagcd +Ti+p+lle+l+k+++t + ++ ++++k l+ek+fr+ ++eda+a+ FUN_001395-T1 200 DPGVKSVTKIYNYYKKFDYKTVVMGASFRNTGQITELAGCDLLTISPSLLEKLQKSTETvslklsvD-EAkkQDIDKisLNEKKFRWLLNEDAMAT 294 **********************************************************976666432.224577777999**************** PP TAL_FSA 265 elldegvrkFakdwekllksl 285 ++l+eg+rkFa+d+ kl++++ FUN_001395-T1 295 DKLAEGIRKFAADAVKLEEMI 315 *****************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1265 (0.0495205); expected 510.9 (0.02) Passed bias filter: 798 (0.031239); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.43s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3245.14 // Query: FUN_001396-T1 [L=309] Description: FUN_001396 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.1e-65 215.1 2.7 1.7e-21 76.3 0.1 3.2 3 Mito_carr Mitochondrial carrier protein Domain annotation for each model (and alignments): >> Mito_carr Mitochondrial carrier protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.8 0.0 5e-22 1.3e-17 3 94 .. 10 115 .. 8 117 .. 0.92 2 ! 76.3 0.1 6.5e-26 1.7e-21 3 95 .. 121 211 .. 119 212 .. 0.96 3 ! 74.0 0.1 3.2e-25 8.2e-21 4 94 .. 217 304 .. 215 306 .. 0.94 Alignments for each domain: == domain 1 score: 63.8 bits; conditional E-value: 5e-22 Mito_carr 3 lsflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskksk..............ildafkkivkeeGirglykGllpnllrvapaaaikfat 84 ++l +++++g+a+ +a +vt P+d++K+rlq+q++++ + ++ + +++k++G+++lykGl+p + r+ +a+i++++ FUN_001396-T1 10 PTILVKFVSAGLAASVAEAVTIPIDTAKVRLQIQGENTVMANVPsgkatanpsvqyrgMIGSMVTVAKTDGFHSLYKGLVPGIHRQLCFASIRIGL 105 678899***************************9999766555567788899999***************************************** PP Mito_carr 85 yetlkklllk 94 y+++k+++ + FUN_001396-T1 106 YDKVKTFYGD 115 ******9976 PP == domain 2 score: 76.3 bits; conditional E-value: 6.5e-26 Mito_carr 3 lsflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklllkk 95 ++++++la+ + g++a+++++P++v+K+r+q++ ++ s+k +lda+k+i++eeGirg++kG +n++r ++ +a ++++y+ +k ++l+k FUN_001396-T1 121 PKVIQKILASFTTGVFAVSLAQPTEVAKVRFQASASRFGSSK--ALDAYKSIYREEGIRGMWKGAFANMARLSVVNASELVVYDLVKGFFLRK 211 57899********************************99977..9********************************************9876 PP == domain 3 score: 74.0 bits; conditional E-value: 3.2e-25 Mito_carr 4 sflasllaGgiagaiaklvtyPldvvKtrlqlqskkskskkskildafkkivkeeGirglykGllpnllrvapaaaikfatyetlkklllk 94 +f +++++ ag+++++++ P+dvvKtr ++++ ++ ++ ++++++ ++k++G+ ++ykG++pn++r + + ++f+++e++k+l+++ FUN_001396-T1 217 NFPLHFVSAFGAGFATTVIASPVDVVKTRYMNSPPNTYKS---AIHCAYMLLKHNGPLAFYKGFTPNFMRLGAWNIVMFVCFEQFKRLFSR 304 68889****************************9997664...9********************************************975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 545 (0.0213349); expected 510.9 (0.02) Passed bias filter: 468 (0.0183206); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 3090.93 // Query: FUN_001397-T1 [L=471] Description: FUN_001397 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-20 72.0 36.5 1.5e-11 44.4 14.3 2.3 2 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 1.7e-13 51.5 0.0 3.5e-13 50.4 0.0 1.6 1 FERM_M FERM central domain 1.7e-13 50.7 0.0 4e-13 49.5 0.0 1.7 1 FERM_N FERM N-terminal domain 3.3e-07 31.1 1.6 4.5e-07 30.7 0.2 1.9 2 FERM_C FERM C-terminal PH-like domain 0.0029 18.1 0.0 0.2 12.3 0.0 2.8 2 RA_2 RA like domain ------ inclusion threshold ------ 0.02 15.2 37.6 0.5 10.8 16.4 2.6 2 Prok-RING_4 Prokaryotic RING finger family 4 2.8 8.5 42.0 1.6 9.3 15.6 2.6 2 zf-RING_5 zinc-RING finger domain Domain annotation for each model (and alignments): >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.5 14.2 1e-11 3.8e-08 4 48 .. 349 390 .. 347 391 .. 0.95 2 ! 44.4 14.3 4.2e-15 1.5e-11 4 47 .. 406 446 .. 403 448 .. 0.94 Alignments for each domain: == domain 1 score: 33.5 bits; conditional E-value: 1e-11 zf-C3HC4_3 4 eCviClerernvvllpCgHlclCeeCaeklrkkkkCpiCrqkies 48 +C C ++e+nv+++pCgHl++Ce+C +k ++C++C+ ++s FUN_001397-T1 349 KCSRCGQEEANVLFTPCGHLVCCEDCVRKG---TTCVVCNCTVTS 390 8*****************************...******998875 PP == domain 2 score: 44.4 bits; conditional E-value: 4.2e-15 zf-C3HC4_3 4 eCviClerernvvllpCgHlclCeeCaeklrkkkkCpiCrqkie 47 C+iC+++e+n+++ pCgH+c Ce+Ca +l + CpiC++ i+ FUN_001397-T1 406 ACQICMDSEINTAFSPCGHVCSCESCACHL---PYCPICKTFIT 446 6*****************************...*******9987 PP >> FERM_M FERM central domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.4 0.0 9.6e-17 3.5e-13 3 117 .] 86 190 .. 84 190 .. 0.94 Alignments for each domain: == domain 1 score: 50.4 bits; conditional E-value: 9.6e-17 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF FERM_M 3 esklqdevtrellYlQlkrdllegrlpcseeeallLAaLqlqaelgdyssesheseylslesflpkqllkklkskelekrvleahkklrglsaeeA 98 +++lq+e tr+++Yl l++++ eg++ ++e+a++L aL++qae+gd+s + +s +fl + +++e++++ h++l+g s + A FUN_001397-T1 86 PQELQQEETRRQFYLCLRKQISEGKFNFTQEKAVQLCALMAQAEYGDFSRP-----PKSFPQFLSPW-----PGEDMERKIAGSHRNLEGTSSTIA 171 6799********************************************977.....44567788888.....889********************* PP xxxxxxxxxxxxxxxxxxx RF FERM_M 99 klkylqiaqslptyGvelF 117 + +l+i+++ + y +e+F FUN_001397-T1 172 RDAFLNIMSKEDLYDAEVF 190 ****************999 PP >> FERM_N FERM N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.5 0.0 1.1e-16 4e-13 4 63 .. 8 66 .. 5 67 .. 0.95 Alignments for each domain: == domain 1 score: 49.5 bits; conditional E-value: 1.1e-16 FERM_N 4 LDgtklefevqkkatgqelLdqVckhlnlkEkdyFGLqfldsksehrWLdlekklekqak 63 +Dg+ +ef ++ + gqe Ld+Vc++l++kEk yFGL++ ++ +WL+l+++l+ q++ FUN_001397-T1 8 PDGRAHEFVLTGDKLGQEALDKVCEKLGIKEKNYFGLRHSVND-ADIWLNLRNPLSTQFR 66 89**************************************999.9************986 PP >> FERM_C FERM C-terminal PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 1.6 5.8e+03 42 65 .. 95 115 .. 81 127 .. 0.67 2 ! 30.7 0.2 1.2e-10 4.5e-07 5 91 .. 197 284 .. 193 286 .. 0.93 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.6 FERM_C 42 rkkfliklrkeedkkkeetleFkl 65 r++f++ lr ++ +e ++ F+ FUN_001397-T1 95 RRQFYLCLR---KQISEGKFNFTQ 115 667777777...555555555554 PP == domain 2 score: 30.7 bits; conditional E-value: 1.2e-10 FERM_C 5 tellLGvsakGilvyekkdki.pknlFpWseirkisfkrkkfliklrkeedkkkeetleFklessrackslwklcveqhkffrlrkss 91 +++l++v ++G+ vye ++ +k++ ++i k++ ++ ++++ lrk ++++k + + F l+s +a+k + k +e++ ff ++k + FUN_001397-T1 197 QKVLVAVGSNGLRVYERRTHGkLKQSIGFESIIKMNLSEERLIVVLRKMSENSKLNFVHFFLASDDAAKAIHKAVMEHQLFFYSSKVR 284 7899***********99999889**********************************************************9887765 PP >> RA_2 RA like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.0 5.4e-05 0.2 6 54 .. 4 53 .. 1 59 [. 0.86 2 ? 2.7 0.0 0.052 1.9e+02 12 44 .. 158 190 .. 156 191 .. 0.91 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 5.4e-05 RA_2 6 kvflmDgsskavevdsattarevceklaeklglkdsegFsLyeslpdk.v 54 v+ +Dg+ ++ + +e+++k++eklg+k+++ F+L s++d + FUN_001397-T1 4 AVLEPDGRAHEFVLTGDKLGQEALDKVCEKLGIKEKNYFGLRHSVNDAdI 53 67778999999999999999*********************999988755 PP == domain 2 score: 2.7 bits; conditional E-value: 0.052 RA_2 12 gsskavevdsattarevceklaeklglkdsegF 44 gs +++e s+t ar++ ++++k +l d e F FUN_001397-T1 158 GSHRNLEGTSSTIARDAFLNIMSKEDLYDAEVF 190 78999*******************999998766 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 13.1 0.00028 1 1 37 [. 350 385 .. 350 393 .. 0.79 2 ? 10.8 16.4 0.00014 0.5 1 38 [. 407 443 .. 407 448 .. 0.92 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00028 Prok-RING_4 1 CvlcgreetkivlspCgHl.vCkeCfdssdfsaCPiCr 37 C+ cg+ee++ pCgHl C++C + C +C+ FUN_001397-T1 350 CSRCGQEEANVLFTPCGHLvCCEDCVRK--GTTCVVCN 385 999****************557889754..34577776 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00014 Prok-RING_4 1 CvlcgreetkivlspCgHl.vCkeCfdssdfsaCPiCrr 38 C +c e++ + spCgH+ C++C + + CPiC+ FUN_001397-T1 407 CQICMDSEINTAFSPCGHVcSCESCACHLPY--CPICKT 443 99*****************99****998877..9***85 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 15.6 0.00043 1.6 4 42 .. 349 385 .. 348 386 .. 0.81 2 ? 4.6 18.4 0.012 45 2 43 .] 402 443 .. 401 443 .. 0.83 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00043 zf-RING_5 4 kCfkelsktrkfyltsCgHif.CeeClkklleerqCpiCk 42 kC+++ +++ ++ +t+CgH++ Ce+C+ k + +C +C+ FUN_001397-T1 349 KCSRCGQEEANVLFTPCGHLVcCEDCVRKGT---TCVVCN 385 555555666**********75279*******...*****7 PP == domain 2 score: 4.6 bits; conditional E-value: 0.012 zf-RING_5 2 Cn..kCfkelsktrkfyltsCgHif.CeeClkklleerqCpiCkk 43 Cn C + +++ + + +CgH++ Ce+C+++l CpiCk+ FUN_001397-T1 402 CNdwACQICMDSEINTAFSPCGHVCsCESCACHLP---YCPICKT 443 55555666667779999******977*********...*****96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (471 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1265 (0.0495205); expected 510.9 (0.02) Passed bias filter: 507 (0.0198473); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4658.03 // Query: FUN_001398-T1 [L=308] Description: FUN_001398 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-27 95.6 15.5 5.6e-27 95.3 15.5 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.9e-13 50.9 13.7 8e-12 45.5 13.7 2.1 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 1e-06 28.8 14.9 1.7e-06 28.1 14.8 1.5 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 1.8e-06 28.1 14.2 3e-06 27.3 14.2 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.00074 19.7 14.1 0.0018 18.4 14.1 1.7 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 0.00099 19.6 3.5 0.00099 19.6 3.5 2.2 3 Serpentine_r_xa Caenorhabditis serpentine receptor-like prot ------ inclusion threshold ------ 0.16 12.1 20.6 0.49 10.5 20.6 1.8 1 Srg Srg family chemoreceptor 0.19 12.1 1.3 0.67 10.3 1.3 1.9 1 TssO Type VI secretion system, TssO Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.3 15.5 1.8e-30 5.6e-27 2 260 .] 18 271 .. 17 271 .. 0.86 Alignments for each domain: == domain 1 score: 95.3 bits; conditional E-value: 1.8e-30 xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxx...xxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrt.ptnifllnLavaDllvll..lvlpfalvyallegdwvf...gevlCklvt..aldvvnltasillltaisiDRYlaIvk 89 Nl+ ++v+++++++ + + ni l++Lav+Dll+++ +++p ++ ++ e+ ++ g+++C+l+ +l ++++ +sill ++++++R+ ++ + FUN_001398-T1 18 NLFFCIVLVTKRSMLKkSHNIVLFSLAVTDLLTGIflVATPGYVIPKA-EYPIPTglhGQIFCRLLAnrYLLFLMGKVSILLAACLALERWYCVLR 112 8899999999998666488**************986566677776666.4555555568999**9753388888888******************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 90 plkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksak 185 p++y+++ +++r+++++ +++++ ++ls+ ++ + + C + ++ ++ +++++s l+f++p+++ ++ ++i + + + FUN_001398-T1 113 PMQYRNMFSRKRVFIYVTLMFIVTCILSMNKFFEN--N-----VVKDKCITKNAPYGKYGTRAFIVVYSSLAFYIPCFITWFTFAHISLHFPSFQG 201 *******************************9933..2.....34678988887777788889999999999***************999988887 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 kekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + ++ + ++r++r +l++ ++ v+ ++c +P +++ ll+ + + +k+ + + + ++ l +++sc+NP+iY FUN_001398-T1 202 QTRE-SVNKKRRQRALLRMCAITAVALTICGFPAQTIYLLSPF----DITKIGSPLHKGFNALLLLHSCMNPLIY 271 7776.444557788999**************************....999999999******************* PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.5 13.7 2.5e-15 8e-12 4 319 .] 8 289 .. 5 289 .. 0.81 Alignments for each domain: == domain 1 score: 45.5 bits; conditional E-value: 2.5e-15 7TM_GPCR_Srw 4 filsivgviinifHliiL.trksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlile.slkdvsrrcstwlgv 97 ++++ +++ n+f +i+L t++sm + s ni++ + a+ D+lt ++ + + + i + + +p+ + +++++l+++ l ++ ++s+ l+ FUN_001398-T1 8 CVIAAASFSSNLFFCIVLvTKRSMLKKSHNIVLFSLAVTDLLTGIFLVATPG-YVIPK--AEYPIPTGLHGQIFCRLLANrYLLFLMGKVSILLAA 100 58999************956779**********************9999998.45554..6777999999999999877527888999******** PP 7TM_GPCR_Srw 98 lmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifl 193 ++Al R+ v p++ +++ + k ++ +++++++++++s+ k+f++++v+++ C ++ y +++ f+ FUN_001398-T1 101 CLALERWYCVLRPMQY--RNMFSRKRVFIYVTLMFIVTCILSMNKFFENNVVKDK--------CI--TK---NAPYGKYGTRA-----------FI 170 ***********99975..578999999*************************555........96..23...33444333333...........44 PP 7TM_GPCR_Srw 194 lidgilskiipsillpiltilLiieLrkakksrkklskskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifsll 289 ++ + l ip+++ ++ + +++++ ++ +++++ ++ + ++ +i +p iy+++ + +i++i + l f++l FUN_001398-T1 171 VVYSSLAFYIPCFITWFTFAHISLHFPSFQGQTRESVNK--KRRQRALLRMCAITAVALTICGFPAQTIYLLSPF-----DITKIGSPLHKGFNAL 259 444555568999997765555444444444443333323..3478888999999999999999999999999765.....6889************ PP 7TM_GPCR_Srw 290 ltinsisHflicllmSsqYRktvkklfgck 319 l+++s++ li+ l +YR+ +kk++gc+ FUN_001398-T1 260 LLLHSCMNPLIYWLTNKEYRREFKKMLGCN 289 ****************************95 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 14.8 5.3e-10 1.7e-06 16 283 .] 20 288 .. 6 288 .. 0.71 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 5.3e-10 7TM_GPCR_Srv 16 licllklrkrsktfkttFYklllqhaiaDiitllvyiv..gavfrklgwieefyfelqeyy.aaiyyniayytliirctgivlLslqRllaillPi 108 ++c++ + krs ++k +l++ a+ D++t ++ ++ g v++k + + ++ q ++ + + + ++ + ++ L+l+R +l+P+ FUN_001398-T1 20 FFCIVLVTKRS-MLKKSHNIVLFSLAVTDLLTGIFLVAtpGYVIPKAEYPIPTGLHGQIFCrLLANRYLLFLMGKVSILLAACLALERWYCVLRPM 114 55666666666.66666667777777777777655544125667777777777777777766666667777888888888999************* PP 7TM_GPCR_Srv 109 srltkivqsaklwkiilvywlvgllislvvlkdtdieydneenmpvvadksvierftlialivvvvtciiliiayvllfvvlrkkkk.....kksq 199 +++++ + ++ ++ +++ ++v ++s+ ++++++ d+ + ++ + ++ t+ + vv + ++ i ++++ f++ + + + +++ FUN_001398-T1 115 -QYRNMFSRKRVFIYVTLMFIVTCILSMNKFFENNVVKDKCIT----KNAPYGKYGTRAFI-VVYSSLAFYIPCFITWFTFAHISLHfpsfqGQTR 204 .******************999999999888877766555433....33333333333322.2222333333444444444443222233337777 PP 7TM_GPCR_Srv 200 tkskslkrevrLaiqvlilvlaqliilifyilklyfsqtlntdp.ifylRalYpilsgllsyinPylllilskdlrkqvlkrlkc 283 ++ ++++r+ L +++i+ ++ l+i f + y ++ + l + +++l l s +nP + ++ +k+ r+++ k+l+c FUN_001398-T1 205 ESVNKKRRQRALLRMCAIT-AVALTICGFPAQTIYLLSPFDITKiGSPLHKGFNALLLLHSCMNPLIYWLTNKEYRREFKKMLGC 288 7888999999999988876.556888888888888777766665367899********************************998 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 14.2 9.3e-10 3e-06 7 257 .] 17 286 .. 8 286 .. 0.69 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 9.3e-10 7TM_GPCR_Srsx 7 GNvll.illtfkkkkLrskssiLicvqcladllclvgelvfvvllltgtql.......kreeCFlliivyvfgltaqsvllLv..igiDlliavkf 92 +N+ + i+l+ k++ L+ +i ++ +++ dll ++ +++ + + ++ + C ll y+++l+ + +lL+ +++ + ++v FUN_001398-T1 17 SNLFFcIVLVTKRSMLKKSHNIVLFSLAVTDLLTGIFLVATPGYVIPKAEYpiptglhGQIFCRLLANRYLLFLMGKVSILLAacLALERWYCVLR 112 566553777888889999999999999999999888777665555544433111111158899999*********9999999644899******** PP 7TM_GPCR_Srsx 93 PirYrllskekYllillifpvlyssiilvlgflqrdde..tiivCapplalagkaseiftlssliinvivllvylvliii......lkkkkek... 177 P++Yr++ ++k ++i +++ ++ ++i+ + f++ + i+ ++p + g+ i +ssl++++ ++ +++ +i + + FUN_001398-T1 113 PMQYRNMFSRKRVFIYVTLMFIVTCILSMNKFFENNVVkdKCITKNAPYGKYGTRAFIVVYSSLAFYIPCFITWFTFAHIslhfpsF-----Qgqt 203 ***********7777777777777777666666655322245555666666565555666666666665555444444443344442.....2223 PP 7TM_GPCR_Srsx 178 .....kkssskkvlkslkvt.vvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrell 257 kk++ +++l+ ++t v + i+g ti + +t+ + +++ l+ll ++ n ++ + ++eYr++f+++l FUN_001398-T1 204 resvnKKRRQRALLRMCAITaVALTICGFPAQTIYLLSPFDITK---IGSPLHKGFNALLLLHSCMNPLIYWLTNKEYRREFKKML 286 556668999999***99987477888887777776655554444...4445677777788888899999**************985 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 14.1 5.5e-07 0.0018 9 208 .. 16 215 .. 9 243 .. 0.65 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 5.5e-07 7TM_GPCR_Srx 9 vlNllvliai.lklkslknsFgilclskaisnaiilliflf...yvvPmtllqsell...kellnshliglialglYeisplsqllialNRfcavf 97 Nl++ i++ k++ lk+s +i +s a+ ++++ +++++ yv+P ++++ + ++ + ++++++ +s+l+ ++al+R + v FUN_001398-T1 16 SSNLFFCIVLvTKRSMLKKSHNIVLFSLAVTDLLTGIFLVAtpgYVIPKAEYPIPTGlhgQIFCRLLANRYLLFLMGKVSILLAACLALERWYCVL 111 567776665515666679**************876544433111555555555555543333333334455555555678888999********** PP 7TM_GPCR_Srx 98 fplkyekifsiknTkiiiviiwivslifitvlylpegCkllynpetltwsfeeteccktiswyldfllililviitlvlnlltaiklilskkksks 193 p++y ++fs+k +i++++++iv+ i ++ + +e+ + ++ + +++ + k + + ++ + + + i +++ +t+ + l+ + + FUN_001398-T1 112 RPMQYRNMFSRKRVFIYVTLMFIVTCILSMNKF-FENNVVK--DKCI---TKNAPYGKYGTRAFIVVYSSLAFYIPCFITWFTFAHISLHFPSFQ- 200 ***************************766544.4433333..3333...334444444444443344455556667777777777776666665. PP 7TM_GPCR_Srx 194 tsseeskrrrkrein 208 +++es ++++r++ FUN_001398-T1 201 GQTRESVNKKRRQRA 215 444444444444443 PP >> Serpentine_r_xa Caenorhabditis serpentine receptor-like protein, class xa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.3 2.2 7.1e+03 73 99 .. 23 49 .. 6 57 .. 0.57 2 ! 19.6 3.5 3.1e-07 0.00099 57 110 .. 94 147 .. 82 155 .. 0.88 3 ? -3.9 0.0 5.3 1.7e+04 28 44 .. 271 287 .. 259 292 .. 0.62 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 2.2 Serpentine_r_xa 73 vikPlkqkiwftdkkvvlysvivlilv 99 ++ +k++++ +++vl+s v+ l+ FUN_001398-T1 23 IVLVTKRSMLKKSHNIVLFSLAVTDLL 49 444444445555566666666665444 PP == domain 2 score: 19.6 bits; conditional E-value: 3.1e-07 Serpentine_r_xa 57 iplflsvlmtlqRisivikPlkqkiwftdkkvvlysvivlilvlilLlipylse 110 + + l ++l+R + v++P++ + +f+ k+v++y +++ i+++il + +++ + FUN_001398-T1 94 VSILLAACLALERWYCVLRPMQYRNMFSRKRVFIYVTLMFIVTCILSMNKFFEN 147 678889999********************************9999988887765 PP == domain 3 score: -3.9 bits; conditional E-value: 5.3 Serpentine_r_xa 28 elvlpeeeYeeyRklig 44 ++++++e e++k++g FUN_001398-T1 271 YWLTNKEYRREFKKMLG 287 44444444457887776 PP >> Srg Srg family chemoreceptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 20.6 0.00015 0.49 11 208 .. 14 210 .. 1 249 [. 0.60 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00015 Srg 11 slilmililililvskkeeyrsnsFyrLytlDlivnlllllldiffvRlflyvpplcifllkf..fkeppifltiyyylynyflhakflsqillsv 104 s+ ++++ i+++ ++ ++++s +++++ l+v+ ll if+v yv p ++ ++ ++ + l yl++ + + +l +++l++ FUN_001398-T1 14 SFSSNLFFCIVLVTKRS--MLKKS-HNIVLFSLAVTD--LLTGIFLVATPGYVIPKAEYPIPTglHGQIFCRLLANRYLLFLMGKVSILLAACLAL 104 34445555555555555..43444.344444444332..22455555555555565555555523556666666667788888888899******* PP Srg 105 nRmssVlfpvkhekiWkkylklvlivifilpflfiwnvlisrveveivnggfsinyekavp...wastslfqliyfilalvltlittivtlkklkk 197 +R +Vl p++++++ ++ ++++++++++ +++ ++++v v+++ ++ ++ + a + +++++ f + +++t +t+ ++ ++ + FUN_001398-T1 105 ERWYCVLRPMQYRNMFSRKRVFIYVTLMFIVTCILSMNKFFENNV--VKDKCITKNAPYGKygtRAFIVVYSSLAFYIPCFITWFTFAHISLHFPS 198 *******************95555555555555444444444433..3444444444444454466666777777777778888888888888888 PP Srg 198 ls.krlksverk 208 ++ ++ +sv +k FUN_001398-T1 199 FQgQTRESVNKK 210 886666666655 PP >> TssO Type VI secretion system, TssO # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 1.3 0.00021 0.67 6 35 .. 122 150 .. 118 159 .. 0.79 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00021 TssO 6 rrsgflkflllFlvttlllffilffnyksl 35 r++ f++++l+F+vt++l + +f n++ + FUN_001398-T1 122 RKRVFIYVTLMFIVTCILSMNKFFENNV-V 150 6778************999977766665.4 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (308 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1050 (0.0411039); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.39 # Mc/sec: 3172.07 // Query: FUN_001399-T1 [L=118] Description: FUN_001399 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (118 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 428 (0.0167547); expected 510.9 (0.02) Passed bias filter: 327 (0.0128009); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.36s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 1240.76 // Query: FUN_001400-T1 [L=391] Description: FUN_001400 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-31 109.4 14.9 3.8e-31 109.0 14.9 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 4.4e-08 33.3 8.4 7.3e-08 32.6 8.4 1.3 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 3.3e-05 24.1 6.0 3.3e-05 24.1 6.0 2.4 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx ------ inclusion threshold ------ 0.57 10.6 6.5 0.48 10.9 0.9 2.5 2 Serpentine_r_xa Caenorhabditis serpentine receptor-like prot Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.0 14.9 6e-35 3.8e-31 2 260 .] 60 313 .. 59 313 .. 0.84 Alignments for each domain: == domain 1 score: 109.0 bits; conditional E-value: 6e-35 xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkk.lrtptnifllnLavaDllvll..lvlpfalvyal..legdwvfgevlCklvtaldvvnlt..asillltaisiDRYlaIvkp 90 Nl+ +lv++++++ lr+p n++l+nLa++Dll+++ +v+p ++ + ++ + g+++C l+ ++++++ +sill+t+++++R+ ++++p FUN_001400-T1 60 NLMFCLVLFKKREmLRKPHNMLLFNLAITDLLTGIllVVTPGYVSREPlfPVSSGPGGHIFCSLLANRYLLFTVakVSILLVTCLAVERWYCVMRP 155 99999999999884566***************9976677787777664224477888******987555555553389****************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 91 lkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe.eestwevsytlllsvlgfllpllvilvcyvrilrtlrksak 185 ++y+ + ++++ l++il+ Wv ++l +l ++ +++++C+ +++ ++++++++++++ f+ p++v + ++i ++ a+ FUN_001400-T1 156 VEYNIKFNRKHLLIYILLSWVTTCALQSHKFLEMK-------SGDYECVTVDVPySREGAQAFIAIYSFIV-FVSPCIVTWLTFAHIRCHPTGVAR 243 ******************************99554.......57789976555514444777777776665.888****99999999999999999 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 186 kekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + + +++++++++ +l++ ++ vv ++cw+P ++ l+ + ++++ ++ + ++++a++nsc+NP+iY FUN_001400-T1 244 PSGE-SARREKQQKLVLRMCAITAVVITICWFPAQLSYSLTPF----GITRVSGAFHKTCNVVAFCNSCINPFIY 313 9887.566667778999*************************9....99************************** PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.6 8.4 1.1e-11 7.3e-08 13 278 .. 59 325 .. 47 329 .. 0.77 Alignments for each domain: == domain 1 score: 32.6 bits; conditional E-value: 1.1e-11 7TM_GPCR_Srv 13 llilicllklrkrsktfkttFYklllqhaiaDiitllvyivgavfrkl.gwieefyfelqeyyaaiyyniayytliirctgivl...LslqRllai 104 + +++cl+ +kr+ +++ + ll+ ai D++t + +v+ + ++++ +++ + + y +++ ++i+l L+++R + FUN_001400-T1 59 FNLMFCLVLFKKRE-MLRKPHNMLLFNLAITDLLTGILLVVTPGYVSRePLFPVSSGPGGHIFCSL-LANRYLLFTVAKVSILLvtcLAVERWYCV 152 55678888888888.99***************9987766665544333023333333334433333.4445666666666654433399******* PP 7TM_GPCR_Srv 105 llPisrltkivqsaklwkiilvywlvgllislvvlkdtdieydneenmpvvadksvierftlialivvvvt.ciiliiayvllfvvlrkkkk..kk 197 ++P +++ + + ++l++ il+ w++ +++ +++++ + ++ v ++++ + f i ++v+v+ ci+ l+f +r + + + FUN_001400-T1 153 MRPV-EYNIKFNRKHLLIYILLSWVTTCALQSHKFLEMKSGDYECVTVDVPYSREGAQAFIAIYSFIVFVSpCIVT----WLTFAHIRCHPTgvAR 243 ****.***************************99998888777788899999999999999999988886523333....3456666644445577 PP 7TM_GPCR_Srv 198 sqtkskslkrevrLaiqvlilvlaqliilifyilklyfsqtlntdp.ifylRalYpilsgllsyinPylllilskdlrkqvl 278 ++ s ++++ +L + ++ +++++++i f + y+ + + + ++ + ++++ s inP++ + + ++ rk++ FUN_001400-T1 244 PSGESARREKQQKLVLRMCAITAVVITICWFPAQLSYSLTPFGITRvSGAFHKTCNVVAFCNSCINPFIYWYYHREYRKELA 325 88999999999********************999999998776655367888899********************9999876 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 6.0 5.1e-09 3.3e-05 8 207 .. 57 256 .. 51 274 .. 0.73 2 ? 0.0 2.0 0.11 7.3e+02 23 43 .. 289 309 .. 268 317 .. 0.81 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 5.1e-09 7TM_GPCR_Srx 8 lvlNllv.liailklkslknsFgilclskaisnaiilliflfyvvPmtllqsell.......kellnsh.liglialglYeisplsqllialNRfc 94 +++Nl++ l+ + k++ l+++ ++l ++ ai +++ + +l++v+P +++ +l+ +++ s + ++++++ +s+l+ +++a++R + FUN_001400-T1 57 FMFNLMFcLVLFKKREMLRKPHNMLLFNLAITDLL--TGILLVVTPGYVSREPLFpvssgpgGHIFCSLlANRYLLFTVAKVSILLVTCLAVERWY 150 567876615566777888***************86..556677777777766666333333333333333677888889999************** PP 7TM_GPCR_Srx 95 avffplkyekifsiknTkiiiviiwivslif.itvlylpegCkllynpetltwsfeeteccktiswyldfllililviitlvlnlltaiklilskk 189 v+ p+ y+ f++k i+i+++w+++ + + +++ + y+ t+ ++++ ++i+ y+ +i+++ +++ lt+ ++++ + FUN_001400-T1 151 CVMRPVEYNIKFNRKHLLIYILLSWVTTCALqSHKFLEMK--SGDYECVTVDVPYSREGAQAFIAIYS-----FIVFVSPCIVTWLTFAHIRCHPT 239 ***************************9997566666666..55688888888888899999999997.....55666666666788999998888 PP 7TM_GPCR_Srx 190 kskstsseeskrrrkrei 207 + s es+rr+k++ FUN_001400-T1 240 GVA-RPSGESARREKQQK 256 887.55555444444433 PP == domain 2 score: 0.0 bits; conditional E-value: 0.11 7TM_GPCR_Srx 23 slknsFgilclskaisnaiil 43 + + +F++ c + a++n++i FUN_001400-T1 289 RVSGAFHKTCNVVAFCNSCIN 309 56789************9986 PP >> Serpentine_r_xa Caenorhabditis serpentine receptor-like protein, class xa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.9 7.6e-05 0.48 49 94 .. 129 173 .. 122 185 .. 0.84 2 ? 2.2 0.5 0.036 2.3e+02 47 126 .. 212 298 .. 199 327 .. 0.66 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 7.6e-05 Serpentine_r_xa 49 lvgtlfYliplflsvlmtlqRisivikPlkqkiwftdkkvvlysvi 94 l++t++ + +l +++l +++R + v++P++ +i f+ k++++y + FUN_001400-T1 129 LLFTVAKVSILLVTCL-AVERWYCVMRPVEYNIKFNRKHLLIYILL 173 6788888888888876.89***********************9765 PP == domain 2 score: 2.2 bits; conditional E-value: 0.036 Serpentine_r_xa 47 itlvgtlfYliplflsvlmtlq.Ris..ivikPlkqki.wftdkk.vvlysvivlilvlilLlipylse..CsvnfnartlsfesaC 126 i++ ++++ p ++++l + R + v +P ++ ++k v+ +++i +++++i + +ls+ + + + f+ C FUN_001400-T1 212 IAIYSFIVFVSPCIVTWLTFAHiRCHptGVARPSGESArREKQQKlVLRMCAITAVVITICWFPAQLSYslTPFGITRVSGAFHKTC 298 677777888888888887554435542257888754431344555145577777777777666555554114555555555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (391 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1076 (0.0421217); expected 510.9 (0.02) Passed bias filter: 530 (0.0207477); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3832.93 // Query: FUN_001401-T1 [L=244] Description: FUN_001401 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-66 224.1 3.1 3.3e-66 223.7 3.1 1.1 1 FAM60A Protein Family FAM60A ------ inclusion threshold ------ 0.31 11.8 3.0 1.2 9.9 3.0 1.9 1 zf-AD Zinc-finger associated domain (zf-AD) Domain annotation for each model (and alignments): >> FAM60A Protein Family FAM60A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 223.7 3.1 2.6e-70 3.3e-66 1 204 [. 2 226 .. 2 228 .. 0.70 Alignments for each domain: == domain 1 score: 223.7 bits; conditional E-value: 2.6e-70 FAM60A 1 fsfhkpkvyrsaeGCCiCkakssssrftdskkYekefeeCfkleekrsGeiCnaCvLLvkrwkkLPagskrnWkhvvdaragpglkslkkakkk.. 94 f++h+p+v+rs+ GCCiC akssssrft+s kYe f Cf l+e+r+GeiCnaCvLLvkrwkkLP+gs++nWkhvvd++a +k+ +k +++ FUN_001401-T1 2 FASHRPRVFRSRLGCCICGAKSSSSRFTSSTKYELLFSGCFLLSEERQGEICNACVLLVKRWKKLPPGSSKNWKHVVDSKAT--VKKTTKPRRSsr 95 789****************************************************************************975..333333332222 PP FAM60A 95 ..........kkisekaakklkkkkklkkkkakasda.............sseereaspasse..........sasedsdekedeelkkrkaklek 157 + +l++ ++++ ++++ + s + +asp+ s s+ s++ + +++++++ l + FUN_001401-T1 96 tlslenekdvT--------TLSNGRSTSGRSNN---SrdeeeletdsgglSPTLMCASPSPSAsdvsdefpsgSI--ASHSVKRVSTASQTSFLFP 178 33332222221........22222222221111...122344455556664444444444444224444442222..2222233333355667778 PP FAM60A 158 kkersssekvsfldesywkrekvCCGiifkglsgevlidpkllkp.Ce 204 + ++s+++k++f+d+s w+re++CCG+if+g++gevl+dpkll++ C+ FUN_001401-T1 179 SLTSSANNKLPFIDLSTWRREEICCGTIFRGPYGEVLVDPKLLNSmCT 226 9999***************************************98554 PP >> zf-AD Zinc-finger associated domain (zf-AD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 3.0 9.2e-05 1.2 21 61 .. 24 66 .. 15 68 .. 0.81 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 9.2e-05 zf-AD 21 se..ktlaelleellgielspkdllpkkiCerCleklqefysF 61 s+ t ++++e l++ ++ +++ + iC+ C+ ++++ ++ FUN_001401-T1 24 SSsrFTSSTKYELLFSGCFLLSEERQGEICNACVLLVKRWKKL 66 2234688999999999999999999999**********99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (244 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 857 (0.0335486); expected 510.9 (0.02) Passed bias filter: 484 (0.018947); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2502.02 // Query: FUN_001402-T1 [L=198] Description: FUN_001402 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-61 207.5 0.2 1.4e-61 207.3 0.2 1.0 1 Ras Ras family 7.7e-20 71.8 0.0 1.4e-19 71.0 0.0 1.4 1 Roc Ras of Complex, Roc, domain of DAPkinase 7.3e-11 42.3 0.0 8.8e-11 42.1 0.0 1.1 1 Arf ADP-ribosylation factor family 1.3e-07 31.9 0.1 4.3e-07 30.2 0.0 1.7 2 GTP_EFTU Elongation factor Tu GTP binding domain 3.3e-05 24.5 0.0 6.6e-05 23.5 0.0 1.5 2 MMR_HSR1 50S ribosome-binding GTPase 8.3e-05 22.9 0.1 0.062 13.6 0.0 2.3 2 RsgA_GTPase RsgA GTPase 0.00012 22.5 2.8 0.001 19.4 0.1 2.0 2 ATP_bind_1 Conserved hypothetical ATP binding protein ------ inclusion threshold ------ 0.02 15.4 0.0 1.7 9.2 0.0 2.2 2 DUF5992 Family of unknown function (DUF5992) 0.075 13.4 0.4 0.3 11.5 0.0 2.0 2 HRI2_3H Heme-regulated eIF-2-alpha kinase, helical domai 0.081 12.9 0.1 0.33 11.0 0.1 2.0 1 FeoB_N Ferrous iron transport protein B Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 207.3 0.2 5.4e-65 1.4e-61 1 161 [. 12 173 .. 12 174 .. 0.99 Alignments for each domain: == domain 1 score: 207.3 bits; conditional E-value: 5.4e-65 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvk.kwle 95 klv+vG +gvGKs+l+++f++++F+++y++Ti +d+++k++ +d++ ++l+i+DTAGqe+f+a+re+y+r++eg+llv+++t+++sf++++ +++ FUN_001402-T1 12 KLVVVGGGGVGKSALTIQFIQSHFVSDYDPTI-EDSYRKQCVIDERVAHLDILDTAGQEEFSAMREQYMRNGEGFLLVFSVTDRASFQEIQtTFHP 106 89******************************.**********************************************************99*** PP Ras 96 eikrvae.envpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvreil 161 +i rv++ +++p++lvGnk+Dle++r+vst+eg+ela+ ++++++etSAk+k+nv++af++lvr+i+ FUN_001402-T1 107 QILRVKDrSEFPMILVGNKSDLEQERTVSTSEGQELASGYKIQYIETSAKQKTNVDQAFHDLVRAIR 173 *******989******************************************************997 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.0 0.0 5.5e-23 1.4e-19 1 119 [] 12 127 .. 12 127 .. 0.84 Alignments for each domain: == domain 1 score: 71.0 bits; conditional E-value: 5.5e-23 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srsse 93 K+v++G +gvGK++l+ +f++++f +++++ti ++ + +++ i++ + +l+i DtaGqe+f+++++ y+r+ ++++lvf + s++ FUN_001402-T1 12 KLVVVGGGGVGKSALTIQFIQSHFVSDYDPTIEDSYRK-QCV-IDE-------RVAHLDILDTAGQEEFSAMREQYMRNGEGFLLVFSvtdRASFQ 98 89*******************************88865.553.333.......4578****************************99765355788 PP Roc 94 nlk.eWlkelkevagks..pvilvgnkiD 119 +++ ++ ++ +v+++s p+ilvgnk D FUN_001402-T1 99 EIQtTFHPQILRVKDRSefPMILVGNKSD 127 87525888888887655459*******98 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.1 0.0 3.5e-14 8.8e-11 7 172 .. 3 170 .. 1 172 [. 0.83 Alignments for each domain: == domain 1 score: 42.1 bits; conditional E-value: 3.5e-14 Arf 7 klklkkkelrilllGLDnaGKtTilkklkleelvt.tiPTigfnvee...veiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRle 98 k ++k+++++++G + GK+ + ++ + ++v+ PTi ++ + + ++ + D Gqe+ + ++Y+++ ++ + v ++dr ++ FUN_001402-T1 3 KAGDADKQYKLVVVGGGGVGKSALTIQFIQSHFVSdYDPTIEDSYRKqcvIDERVAHLDILDTAGQEEFSAMREQYMRNGEGFLLVFSVTDRASFQ 98 566779******************99988877765489***9877653324557789*************************************** PP Arf 99 eakeeLk.alleeeelkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkeglewlse 172 e ++ ++ ++l+ ++ +e ++++++NK Dl++ + ++++ g e + k++ +++sa ++++++++++ l++ FUN_001402-T1 99 EIQTTFHpQILRVKDRSEFPMILVGNKSDLEQERT---VSTSEGQELASGYKIQYIETSAKQKTNVDQAFHDLVR 170 ******9689********************97544...3444444444577788888999999999988888776 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.46 1.2e+03 6 27 .. 13 34 .. 9 56 .. 0.75 2 ! 30.2 0.0 1.7e-10 4.3e-07 65 184 .. 54 170 .. 42 176 .. 0.76 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.46 GTP_EFTU 6 igiighvDhGKtTltdrllykt 27 ++++g GK+ lt + ++ + FUN_001402-T1 13 LVVVGGGGVGKSALTIQFIQSH 34 789999999****998777654 PP == domain 2 score: 30.2 bits; conditional E-value: 1.7e-10 GTP_EFTU 65 etkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveG...vepqteevlrlar...klgvpiivviNKmDrvdeaelkevveevkeellekv 154 +++ ++ ++Dt G ++F+ ++ ++ +g +lv+++++ e qt + +++r + + p+i+v NK D+ +++ + e +el FUN_001402-T1 54 DERVAHLDILDTAGQEEFSAMREQYMRNGEGFLLVFSVTDRasfQEIQTTFHPQILRvkdRSEFPMILVGNKSDLE-QERTVSTSEG--QEL---- 142 5667899********************************99887788898875555411167788**********9.5554444333..345.... PP GTP_EFTU 155 gekgekevpvvpgSalkgegvkellealve 184 +g +++++ +Sa+++ +v++ + lv+ FUN_001402-T1 143 -ASG-YKIQYIETSAKQKTNVDQAFHDLVR 170 .344.36889999**999999976665555 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 2.6e-08 6.6e-05 2 113 .] 13 125 .. 12 125 .. 0.75 2 ? -2.6 0.0 3.3 8.5e+03 66 72 .. 161 167 .. 142 191 .. 0.54 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 2.6e-08 MMR_HSR1 2 vaivGrpNvGKStLinaltgkkaivsdypgtTrdpnegklelkg..kkielvDtpGliegaseee.gleraflaiee.adlillvvdaeeglteld 93 ++vG vGKS L + +++ vsdy t d ++++ +++ ++ ++Dt+G e e+ +++++ ++ e l++ v d+ ++++e++ FUN_001402-T1 13 LVVVGGGGVGKSALTIQFIQS-HFVSDYDPTIEDSYRKQCVIDErvAHLDILDTAG-QE----EFsAMREQYMRNGEgFLLVFSVTDR-ASFQEIQ 101 689****************96.669*********99998885554599********.66....5568999999999956667777773.3354444 PP MMR_HSR1 94 ....eeleelleeekkpvilvlnk 113 +++++ ++++ p+ilv nk FUN_001402-T1 102 ttfhPQILRVKDRSEFPMILVGNK 125 111144555555578899999987 PP == domain 2 score: -2.6 bits; conditional E-value: 3.3 MMR_HSR1 66 lerafla 72 + +af FUN_001402-T1 161 VDQAFHD 167 3333332 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.0021 5.4 109 127 .. 13 31 .. 7 42 .. 0.82 2 ! 13.6 0.0 2.4e-05 0.062 19 99 .. 78 163 .. 59 176 .. 0.72 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0021 RsgA_GTPase 109 tvllGqSGvGKStLinall 127 v++G GvGKS L ++ FUN_001402-T1 13 LVVVGGGGVGKSALTIQFI 31 6899*********976655 PP == domain 2 score: 13.6 bits; conditional E-value: 2.4e-05 RsgA_GTPase 19 ivaNvdqvvivvslke....pefnlrlldrfLvlaeesgiepvivlnKiDlleeeeeleelkkeyealgyev..llvsaktgeglee 99 ++ N + ++v+s+++ +e+++ + ++L + s+ +++v nK Dl +e++ +++ + + a gy++ + +sak+++++++ FUN_001402-T1 78 YMRNGEGFLLVFSVTDrasfQEIQTTFHPQILRVKDRSEFPMILVGNKSDLEQERT-VSTSEGQELASGYKIqyIETSAKQKTNVDQ 163 55677778899998853333466777777899999999*****************9.655555555556555115666666666665 PP >> ATP_bind_1 Conserved hypothetical ATP binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.3 0.028 73 1 19 [. 15 33 .. 15 44 .. 0.80 2 ! 19.4 0.1 3.9e-07 0.001 91 206 .. 58 175 .. 43 191 .. 0.69 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.028 ATP_bind_1 1 vvGpaGsGKttfvgalsei 19 vvG+ G+GK+ ++ ++++ FUN_001402-T1 15 VVGGGGVGKSALTIQFIQS 33 89*********99887764 PP == domain 2 score: 19.4 bits; conditional E-value: 3.9e-07 ATP_bind_1 91 ddyvlfDtPGQielftlseslakiveaLes.efalvavvLvDtrrltd.ptkflsalllalsimlrlelPfvvalnkfDllke...lekelewfed 181 + + ++Dt GQ e+ ++e+ + e+ l + + D ++ t+f + l + r e P++++ nk+Dl +e ++ e + + FUN_001402-T1 58 AHLDILDTAGQEEFSAMREQYM------RNgEGFLLVFSVTDRASFQEiQTTFHPQ---ILRVKDRSEFPMILVGNKSDLEQErtvSTSEGQELAS 144 57789**************998......556999999******9999966666666...889999***************8876663333333333 PP ATP_bind_1 182 vealslllekee......skykklaeaiael 206 ++++++++ + +++++l +ai+++ FUN_001402-T1 145 GYKIQYIETSAKqktnvdQAFHDLVRAIRKF 175 3344444444444434545555555555443 PP >> DUF5992 Family of unknown function (DUF5992) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.024 61 35 65 .. 6 37 .. 1 47 [. 0.78 2 ? 9.2 0.0 0.00065 1.7 29 81 .. 121 173 .. 115 178 .. 0.87 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.024 DUF5992 35 sngdnFaikvegGtGpCa.nkiilFpkskaqs 65 ++++++v gG G+ + +i+F++s+ s FUN_001402-T1 6 DADKQYKLVVVGGGGVGKsALTIQFIQSHFVS 37 55789999999999998746789999987554 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00065 DUF5992 29 evantssngdnFaikvegGtGpCankiilFpkskaqsaevydrafsiaLaalk 81 v n s +++ +++++ G + + ++i++++++a+++ d+af + a++ FUN_001402-T1 121 LVGNKSDLEQERTVSTSEGQELASGYKIQYIETSAKQKTNVDQAFHDLVRAIR 173 567777778888999******************************98888876 PP >> HRI2_3H Heme-regulated eIF-2-alpha kinase, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.00012 0.3 31 60 .. 51 80 .. 24 86 .. 0.85 2 ? -0.6 0.1 0.7 1.8e+03 55 71 .. 158 174 .. 146 183 .. 0.66 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00012 HRI2_3H 31 klicqkLakmglidesyldefssvRsqYqr 60 +i ++ a++ ++d + +efs++R+qY r FUN_001402-T1 51 CVIDERVAHLDILDTAGQEEFSAMREQYMR 80 578889999*******************87 PP == domain 2 score: -0.6 bits; conditional E-value: 0.7 HRI2_3H 55 RsqYqralkqLlkaake 71 + + +a+++L++a ++ FUN_001402-T1 158 KTNVDQAFHDLVRAIRK 174 55556889999887655 PP >> FeoB_N Ferrous iron transport protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.00013 0.33 4 152 .. 14 164 .. 11 168 .. 0.61 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00013 FeoB_N 4 alvGnpnvGkttlfnaltgakqkvgNwpGvtve...kkegklklkekeielvDlPGiYslsalseeekvardflle.ekpdvvvnvvdatnler.n 94 ++vG vGk++l + +++ v+ + t+e +k+++++ + +++++D+ G ++sa+ ++++ + e + +v +v d ++++ + FUN_001402-T1 14 VVVGGGGVGKSALTIQFIQSH-FVSDYDP-TIEdsyRKQCVIDERVAHLDILDTAGQEEFSAMR------EQYMRNgEGFLLVFSVTDRASFQEiQ 101 666777777777766666543.5667654.3331122333344333555555655555444332......23443303355666777766554325 PP FeoB_N 95 LyLtlqllelg....lpvvlalnmideaekkgiki.dlkkLskkLgvpvvktsarkkegieel 152 ++ q+l ++ p++l+ n+ d +++ ++ + ++L++ +++ ++tsa++k+++++ FUN_001402-T1 102 TTFHPQILRVKdrseFPMILVGNKSDLEQERTVSTsEGQELASGYKIQYIETSAKQKTNVDQA 164 66667777664333389*********98888876526799*******************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (198 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1675 (0.0655706); expected 510.9 (0.02) Passed bias filter: 1072 (0.0419652); expected 510.9 (0.02) Passed Vit filter: 111 (0.00434527); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1944.52 // Query: FUN_001403-T1 [L=564] Description: FUN_001403 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-42 146.2 0.0 2.4e-42 145.7 0.0 1.2 1 Pkinase Protein kinase domain 4.2e-16 59.5 0.0 7.2e-16 58.8 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase ------ inclusion threshold ------ 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.7 0.0 2.8e-46 2.4e-42 4 261 .. 221 493 .. 218 494 .. 0.89 Alignments for each domain: == domain 1 score: 145.7 bits; conditional E-value: 2.8e-46 Pkinase 4 leklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdlls....rkga 94 + ++G+G+fg+V k+v++ +g+i+A+K+ k a + +e++++rE+ ++ l p++vr+++++ e+ ++++ Ey+egg+++dl++ + + FUN_001403-T1 221 ICTIGSGQFGSVHKCVNRLDGCIYALKRSLKPVAGSVDEQNAMREVYAHAVLGkNPHVVRYYSAWAEEGHMLIQNEYCEGGSVADLIErnkkSNEV 316 568*************************************************99**********************************77655667 PP Pkinase 95 lseeeakkilkqilegleylHsegvvHrDlKpeNiLid.e.......................kge...lKitDFGlakelessskltsfvgtseY 163 + e e+k++l q+++gl+y+Hs g+ H D+Kp Ni+i+ + k Ki D+G+++ +++ + g+ ++ FUN_001403-T1 317 MGEGELKQVLIQVAQGLKYIHSLGLAHLDIKPGNIFISfSadveecqhsgdegfeendtpgprK-RtpiYKIGDLGHVTSVTNPE---VEEGDCRF 408 9999**********************************66889999998888887766665542.1688**************77...999***** PP Pkinase 164 mAPEvlkskky.gkkvDvWslGvilyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellq 258 +++E+l++ +k+D+++l++++y g+++ + + + ++e+++ +l++ ++is ++ +llk +++ +kR+ta+ l q FUN_001403-T1 409 LPNEILQEDYSsLPKADIFALALTVYLAGGGSHLPK----NGEEWHEIRR----------GNLKFLENISLKMNSLLKLMIDPVADKRPTATALTQ 490 ******77666689**********998866666655....3344666666..........58999******************************* PP Pkinase 259 hpw 261 hp FUN_001403-T1 491 HPV 493 *96 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.8 0.0 8.4e-20 7.2e-16 6 255 .. 223 489 .. 219 491 .. 0.84 Alignments for each domain: == domain 1 score: 58.8 bits; conditional E-value: 8.4e-20 PK_Tyr_Ser-Thr 6 klGeGafGeVykgtlkeekekkkikVavKtl.keeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrkk... 95 ++G+G+fG+V+k+ + + + a+K k a + ++++ ++e+ + l ++p++v+++ + ee+++li ey+egGs+ + ++++ FUN_001403-T1 223 TIGSGQFGSVHKCVNR----LDGCIYALKRSlKPVAGSVDEQNAMREVYAHAVLgKNPHVVRYYSAWAEEGHMLIQNEYCEGGSVADLIERNkks 313 79************99....5666666665438888888899*********9999**************9*99999*************999555 PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse..........................kkvvkisDfGLardvekddyykkkeka 164 +e + el ++ +q+A+G++y++s l H d+ N+++s + + ki+D G +v ++ e + FUN_001403-T1 314 NEVMGEGELKQVLIQVAQGLKYIHSLGLAHLDIKPGNIFISFsadveecqhsgdegfeendtpgprkrTPIYKIGDLGHVTSV------TNPEVE 402 56677789********************************98899999*****************9988899******99999......566666 PP PK_Tyr_Ser-Thr 165 klpikWmapEslkekk.ftsksDvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelv 255 + ++++ E+l+e k+D+++ + +++ + g +++++ n e + +++g +l+ en++ ++++l+k ++ +++Rpt ++l+ FUN_001403-T1 403 EGDCRFLPNEILQEDYsSLPKADIFALALTVY--LAGGGSHLPK--NGEEWHEIRRG-NLKFLENISLKMNSLLKLMIDPVADKRPTATALT 489 778899999*999887345699**99999998..4555555554..33334455544.5788888888888888888888888888888776 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 4e-05 0.34 104 158 .. 305 359 .. 244 364 .. 0.67 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 4e-05 Kdo 104 dLedllaqwae.laeelrrallkavgrlirklhragvqHgdlyakhillqtekeee 158 dL + + +e ++e ++ l +v++ + +h++g+ H d+ + +i++ + + FUN_001403-T1 305 DLIERNKKSNEvMGEGELKQVLIQVAQGLKYIHSLGLAHLDIKPGNIFISFSA-DV 359 444444444446666667788999************************98775.44 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (564 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 459 (0.0179683); expected 510.9 (0.02) Passed bias filter: 415 (0.0162458); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 5546.73 // Query: FUN_001404-T1 [L=486] Description: FUN_001404 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-35 122.9 0.0 1.8e-35 122.1 0.0 1.4 1 DSPc Dual specificity phosphatase, catalytic doma 1.6e-05 25.8 0.0 0.00051 20.9 0.0 2.7 3 Rhodanese Rhodanese-like domain 0.00079 20.4 0.0 0.0013 19.7 0.0 1.3 1 Tc-R-P Polymorphic toxin system, DSP-PTPase phospha ------ inclusion threshold ------ 0.013 16.2 0.0 0.055 14.2 0.0 2.1 2 Init_tRNA_PT Rit1 DUSP-like domain 0.045 14.3 0.2 0.14 12.7 0.0 1.9 2 PTPlike_phytase Inositol hexakisphosphate 0.05 13.7 0.0 0.13 12.3 0.0 1.6 2 Y_phosphatase Protein-tyrosine phosphatase 0.57 9.6 10.4 0.83 9.1 10.4 1.1 1 DUF4647 Domain of unknown function (DUF4647) Domain annotation for each model (and alignments): >> DSPc Dual specificity phosphatase, catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 122.1 0.0 5e-39 1.8e-35 1 132 [. 342 471 .. 342 472 .. 0.97 Alignments for each domain: == domain 1 score: 122.1 bits; conditional E-value: 5e-39 DSPc 1 lylgskstas.lallsklgitlvinvtkevpnaialkkseieylripvedetetkiskyleeavefiekakqkgkkvlVHCqaGisRSatliiaYl 95 +ylg ++a+ +++ ++l++t+vin+ +e +++ i yl+i+++d+ ++++ ++ +a +fi++a +kg+++l+HC+ G+sRS t++iaYl FUN_001404-T1 342 IYLGRGEQATnEKIVADLQLTHVINIGSEHASPFT---DRILYLNIKLDDSPSSDLKVFFLKAFQFISEAFSKGGRILIHCNLGVSRSSTIMIAYL 434 79**99999999***************99988555...9********************************************************* PP DSPc 96 mktknlslneayeflkerrsaispnanfirqLleyer 132 mk+k+++l+ea +f+++rr +i+pn +f++qL ++e+ FUN_001404-T1 435 MKSKQWTLKEAHDFVRDRRTCIRPNRGFLKQLADWEQ 471 ***********************************97 PP >> Rhodanese Rhodanese-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 1.4e-07 0.00051 13 101 .. 207 310 .. 187 311 .. 0.73 2 ? -3.7 0.0 6.5 2.4e+04 59 67 .. 325 333 .. 315 335 .. 0.69 3 ? 1.7 0.0 0.14 5e+02 48 77 .. 398 428 .. 368 448 .. 0.70 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1.4e-07 Rhodanese 13 kvv.liDvRppeeyakghIpgAvnv......sltrlslppapllellekllel.dkdktivvycesgnraaaa.aallkk......lGyknvyvld 93 + +iD+Rp ++y+ ghI A+++ + l + +++ +e ++++ ++ +++vvy+++ ++ +++ +k + + + +l FUN_001404-T1 207 TYMlVIDARPRADYDLGHIILARSLsslyseLASPLFGHGFYSADGPEVIANRlSEFTHVVVYGNEVSDPTNTdLPEIKLlgelmnYEFVDPLFLI 302 44469*********************999986677777777777777777777888*********9999555532223321223224457777777 PP Rhodanese 94 GGfeaWka 101 G++++++ FUN_001404-T1 303 SGYTSFQQ 310 77777765 PP == domain 2 score: -3.7 bits; conditional E-value: 6.5 Rhodanese 59 dkdktivvy 67 ++ k+ivvy FUN_001404-T1 325 RDHKEIVVY 333 778999999 PP == domain 3 score: 1.7 bits; conditional E-value: 0.14 Rhodanese 48 llellekllel.dkdktivvycesgnraaaa 77 +l+ ++ + e +k+ +i+++c+ g + +++ FUN_001404-T1 398 FLKAFQFISEAfSKGGRILIHCNLGVSRSST 428 3444444444489999*********995555 PP >> Tc-R-P Polymorphic toxin system, DSP-PTPase phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 3.7e-07 0.0013 35 103 .. 367 436 .. 348 439 .. 0.76 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 3.7e-07 Tc-R-P 35 elrelgleyqagllvlhvpikDlsaPsekq.veeivrlidalldndkgvvvHCraGvGRtGtvlAsyLvr 103 + e + +++ +l+l + ++D + +k ++ ++i + +++++ + +HC+ Gv R t++ +yL++ FUN_001404-T1 367 IGSEHASPFTDRILYLNIKLDDSPSSDLKVfFLKAFQFISEAFSKGGRILIHCNLGVSRSSTIMIAYLMK 436 5566677788888888888888765555542578899*******************************86 PP >> Init_tRNA_PT Rit1 DUSP-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 3 1.1e+04 15 42 .. 306 332 .. 304 333 .. 0.78 2 ? 14.2 0.0 1.5e-05 0.055 12 63 .. 389 438 .. 378 467 .. 0.83 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 3 Init_tRNA_PT 15 rnLrkaLpkivsfvksklsedkskkilv 42 ++++aLp ++++ + ++++d+ k+i+v FUN_001404-T1 306 TSFQQALPFMCTQKDLTVRRDH-KEIVV 332 5788999999999988888876.66776 PP == domain 2 score: 14.2 bits; conditional E-value: 1.5e-05 Init_tRNA_PT 12 kgsrnLrkaLpkivsfvksklsedkskkilvacetGkDlsvgvaLailcklf 63 s++L+ + k+ +f+++++s++ +il++c+ G s ++++a l+k FUN_001404-T1 389 SPSSDLKVFFLKAFQFISEAFSKGG--RILIHCNLGVSRSSTIMIAYLMKSK 438 55889999999***********997..********************99865 PP >> PTPlike_phytase Inositol hexakisphosphate # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.1 1.5 5.3e+03 52 72 .. 54 77 .. 17 97 .. 0.49 2 ? 12.7 0.0 3.9e-05 0.14 124 156 .. 402 435 .. 391 436 .. 0.88 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.5 PTPlike_phytase 52 aeakktggrvlvheetedge...e 72 e +++++ ++h+ +++++ + FUN_001404-T1 54 MERRDSKNFWISHMRKNSKDslpS 77 344444444445554444442221 PP == domain 2 score: 12.7 bits; conditional E-value: 3.9e-05 PTPlike_phytase 124 vsivket.pedtalvfnCqmGrgRTTtamviatL 156 +++++e+ ++ ++++C +G+ R++t m+ + + FUN_001404-T1 402 FQFISEAfSKGGRILIHCNLGVSRSSTIMIAYLM 435 578888889999*****************99876 PP >> Y_phosphatase Protein-tyrosine phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 1.1 4.1e+03 70 99 .. 45 73 .. 41 112 .. 0.58 2 ? 12.3 0.0 3.6e-05 0.13 156 192 .. 403 435 .. 369 459 .. 0.78 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1.1 Y_phosphatase 70 ivmlteleekgrekceqYwpeeeeesleyg 99 i m e ++++r++ +++w +++++ ++ + FUN_001404-T1 45 IRMNKEAKDMERRDSKNFWISHMRK-NSKD 73 6666777778888888888844433.2222 PP == domain 2 score: 12.3 bits; conditional E-value: 3.6e-05 Y_phosphatase 156 ellekvrkskeeeegpivvhCsaGvgRtgtfiaidil 192 +++++ ++ g i++hC+ Gv+R++t++++ ++ FUN_001404-T1 403 QFISEAF----SKGGRILIHCNLGVSRSSTIMIAYLM 435 3444444....4559*************998876655 PP >> DUF4647 Domain of unknown function (DUF4647) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 10.4 0.00023 0.83 312 431 .. 10 129 .. 5 137 .. 0.85 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00023 DUF4647 312 tkkqeakkkaksdpesqstsrkslstivhdplfGlrtlrgqksdkklqqevkekgallkqdsterpklekaekeldfssskkspelseteltnkdl 407 k + k+++ + +++s+++ ++ dp++G+ ++++ +d++++++++ + ++++s + +++++e +skk++ + + ++++ FUN_001404-T1 10 REKSDKNDKSRKSVRANEASKQRIKDVGGDPTCGRIRMNKEAKDMERRDSKNFWISHMRKNSKDSLPSQTTSNETRETRSKKATPRGRSPKGKRQN 105 56777889***************************9999999**999999988888888888888877888888888999999988888899999* PP DUF4647 408 saeveavleaqaesreetskslsa 431 ++ve+ +ea+a++++ ++ ++s+ FUN_001404-T1 106 AKQVEVLPEAHANNNSPSASNASS 129 ********9999888777666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (486 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1045 (0.0409082); expected 510.9 (0.02) Passed bias filter: 558 (0.0218438); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.36u 0.35s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4812.23 // Query: FUN_001405-T1 [L=465] Description: FUN_001405 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-14 52.0 0.0 2.1e-13 50.9 0.0 1.6 1 BTB BTB/POZ domain 8.6e-09 36.2 0.5 5.8e-06 27.1 0.0 3.1 3 BTB_BTBDG BTBDG BTB/POZ domain ------ inclusion threshold ------ 1.4 9.1 4.5 1.5 9.0 2.1 2.3 2 DENR_N DENR, N-terminal Domain annotation for each model (and alignments): >> BTB BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.9 0.0 2.4e-17 2.1e-13 3 107 .. 55 160 .. 53 163 .. 0.91 Alignments for each domain: == domain 1 score: 50.9 bits; conditional E-value: 2.4e-17 BTB 3 elrekgklcDvtlvvedgkkfkahkavLaacSpyFkalfssk.eeeessvs..eieledvspedfealLefiYtgeleiseenveelLaladklqi 95 l+ g+ +Dvt+ + gk k h+++++ SpyF+++f + +e++++v+ ei+ ++++ e++ + +Y++e+ +s +v lLa+a++lq+ FUN_001405-T1 55 TLFLDGEGSDVTIRAL-GKDWKLHRIYMC-QSPYFQSMFHGSwKESNEEVItlEIPDNNIDIEALNTAFGSLYCDEVTVSPVQVIPLLAAANLLQL 148 67888999********.9*******8875.8***********87778887777888899************************************* PP BTB 96 pslvkkceeflk 107 +l +kc e + FUN_001405-T1 149 IGLSEKCAEVMM 160 *******99875 PP >> BTB_BTBDG BTBDG BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.3 0.0 0.0039 33 1 24 [. 64 87 .. 64 101 .. 0.84 2 ! 27.1 0.0 6.9e-10 5.8e-06 65 122 .] 102 159 .. 92 159 .. 0.96 3 ? 0.3 0.0 0.13 1.1e+03 78 107 .. 212 241 .. 180 243 .. 0.78 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0039 BTB_BTBDG 1 dvileclGfkWelhqpqlfqsetl 24 dv++ lG W+lh+ + qs + FUN_001405-T1 64 DVTIRALGKDWKLHRIYMCQSPYF 87 79999***********99999655 PP == domain 2 score: 27.1 bits; conditional E-value: 6.9e-10 BTB_BTBDG 65 iislkindplvtkvafalalknlylsevelnlddvlgvlasahilqfsslfqrcvalm 122 +i+l i d + a+ +a+ +ly++ev ++ +v+ +la+a +lq+ l ++c ++m FUN_001405-T1 102 VITLEIPDNNIDIEALNTAFGSLYCDEVTVSPVQVIPLLAAANLLQLIGLSEKCAEVM 159 89*****************************************************998 PP == domain 3 score: 0.3 bits; conditional E-value: 0.13 BTB_BTBDG 78 vafalalknlylsevelnlddvlgvlasah 107 ++ + ++l++ ++e+++ ++l v a h FUN_001405-T1 212 MSEIVNSQELFVMQIEVDVYNLLKVWAFVH 241 555566789**************9999776 PP >> DENR_N DENR, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 2.1 0.00018 1.5 4 31 .. 169 195 .. 167 199 .. 0.82 2 ? -2.2 0.0 0.57 4.9e+03 16 25 .. 417 426 .. 417 430 .. 0.85 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.00018 DENR_N 4 CgvCslPpEYCEfgpsfkkCkeWLeknh 31 C C + YCE +kC eWLe + FUN_001405-T1 169 CTYCLAATQYCE-ATVKSKCVEWLERRL 195 8889999*****.44558*******876 PP == domain 2 score: -2.2 bits; conditional E-value: 0.57 DENR_N 16 fgpsfkkCke 25 +++s+ kC e FUN_001405-T1 417 YNSSYYKCSE 426 8999****87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (465 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 623 (0.0243883); expected 510.9 (0.02) Passed bias filter: 478 (0.0187121); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.42s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4533.86 // Query: FUN_001406-T1 [L=321] Description: FUN_001406 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-39 134.4 0.0 1.8e-17 63.5 0.0 3.2 3 RRM_1 RNA recognition motif 4.8e-07 30.3 0.0 0.0058 17.2 0.0 3.1 3 RRM_10 RRM domain 0.0029 18.1 0.0 0.037 14.6 0.0 2.5 2 RNA_bind RNA binding domain ------ inclusion threshold ------ 0.052 13.7 0.2 4.5 7.5 0.0 2.9 3 RRM_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.5 0.0 2.8e-21 1.8e-17 1 70 [] 17 87 .. 17 87 .. 0.97 2 ! 55.8 0.0 7.1e-19 4.5e-15 1 65 [. 103 168 .. 103 173 .. 0.95 3 ! 11.7 0.0 4.1e-05 0.26 1 25 [. 261 285 .. 261 299 .. 0.91 Alignments for each domain: == domain 1 score: 63.5 bits; conditional E-value: 2.8e-21 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd.etgrskgfafVeFedeedaekAlealngkelggrelk 70 l+++ Lp+++t+ e k+lF+ +Gp ks++++r +tg s gf+fVe+ ++e a+ A+++lng +l ++ +k FUN_001406-T1 17 LIINYLPQTLTDLEFKALFQSIGPTKSCKVCRHrSTGYSYGFGFVEYFTPEHAQLAIDTLNGHQLQNKFIK 87 6899***************************************************************9885 PP == domain 2 score: 55.8 bits; conditional E-value: 7.1e-19 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd.etgrskgfafVeFedeedaekAlealngkelg 65 l+++n+p++ t e+L+elF+++G i + ++ ++ g+skg++f+ ++ +++ae+A++a+n++ FUN_001406-T1 103 LYIRNIPKTWTSEDLRELFKPYGNIINSKVLTEpMSGSSKGVGFILYDLKSEAEAAIAAVNNTIPT 168 8************************************************************98655 PP == domain 3 score: 11.7 bits; conditional E-value: 4.1e-05 RRM_1 1 lfVgnLppdvteeeLkelFskfGpi 25 lfV n+ ++t+ ++++lFs++G + FUN_001406-T1 261 LFVYNIGASATQASVYKLFSPYGLF 285 8**********************76 PP >> RRM_10 RRM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.00095 6.1 17 78 .. 23 84 .. 18 93 .. 0.86 2 ! 17.2 0.0 9.1e-07 0.0058 11 82 .. 103 173 .. 100 179 .. 0.87 3 ? 1.6 0.0 0.07 4.5e+02 10 50 .. 260 300 .. 257 309 .. 0.84 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.00095 RRM_10 17 ppdlteeklkevfeeagakapkkvkifpkksersssGlvefesveeAleaLvlaNhtpienp 78 p++lt+ ++k +f++ g ++ kv ++ G+ve+ + e+A a+ +N ++++n+ FUN_001406-T1 23 PQTLTDLEFKALFQSIGPTKSCKVCRHRSTGYSYGFGFVEYFTPEHAQLAIDTLNGHQLQNK 84 8899999********998887777777777777779**********************9996 PP == domain 2 score: 17.2 bits; conditional E-value: 9.1e-07 RRM_10 11 LhFfnappdlteeklkevfeeagakapkkvkifpkksersssGlvefesveeAleaLvlaNhtpienpsgkf 82 L+ n p++ t+e+l+e+f+ g +kv + p + + G++ ++ ++eA +a++++N+t i++ s+++ FUN_001406-T1 103 LYIRNIPKTWTSEDLRELFKPYGNIINSKVLTEPMSGSSKGVGFILYDLKSEAEAAIAAVNNT-IPTGSSEI 173 77789******************999999999999988888********************95.55555555 PP == domain 3 score: 1.6 bits; conditional E-value: 0.07 RRM_10 10 vLhFfnappdlteeklkevfeeagakapkkvkifpkksers 50 +L+ +n + t+ +++++f+ g+ +++ f+kk+ + FUN_001406-T1 260 TLFVYNIGASATQASVYKLFSPYGLFLLEELPNFQKKRTTN 300 68889*******************99999999999995443 PP >> RNA_bind RNA binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 5.7e-06 0.037 15 36 .. 107 128 .. 98 135 .. 0.87 2 ? 0.0 0.0 0.2 1.3e+03 24 35 .. 274 285 .. 268 313 .. 0.79 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 5.7e-06 RNA_bind 15 tFPkeWktsDilqlFspfGqvy 36 Pk+W +D+ +lF+p+G++ FUN_001406-T1 107 NIPKTWTSEDLRELFKPYGNII 128 47*****************985 PP == domain 2 score: 0.0 bits; conditional E-value: 0.2 RNA_bind 24 DilqlFspfGqv 35 +++lFsp+G FUN_001406-T1 274 SVYKLFSPYGLF 285 68999****975 PP >> RRM_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.0 0.0007 4.5 74 101 .. 66 93 .. 56 100 .. 0.87 2 ? 0.3 0.0 0.12 7.6e+02 36 61 .. 109 134 .. 95 165 .. 0.85 3 ? 1.7 0.0 0.043 2.7e+02 15 52 .. 249 283 .. 232 285 .. 0.73 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0007 RRM_5 74 asqvqravqHlngaklfgkkleialSKq 101 ++q+a++ lng++l +k +++alS++ FUN_001406-T1 66 PEHAQLAIDTLNGHQLQNKFIKVALSRK 93 5789**********************87 PP == domain 2 score: 0.3 bits; conditional E-value: 0.12 RRM_5 36 pdkvnldklFnlfclYgnvervkflk 61 p++ + + l lf Ygn+ k+l FUN_001406-T1 109 PKTWTSEDLRELFKPYGNIINSKVLT 134 567788999999******98888775 PP == domain 3 score: 1.7 bits; conditional E-value: 0.043 RRM_5 15 tgtpGvagvaessVllVyglepdkvnldklFnlfclYg 52 ++++G++g + l+Vy++ + + +++ lf+ Yg FUN_001406-T1 249 MPNSGANGA--GFTLFVYNIGASA-TQASVYKLFSPYG 283 333677776..77899****9875.66789****9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 581 (0.0227442); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3196.08 // Query: FUN_001407-T1 [L=327] Description: FUN_001407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-24 86.5 0.6 3.5e-14 53.0 0.1 2.9 3 Beta-prop_THOC3 THOC3 beta-propeller domain 1.3e-15 57.9 0.8 4e-15 56.4 0.8 1.7 1 Beta-prop_WDR5 WDR5 beta-propeller domain 3.4e-15 56.6 1.3 3.8e-13 49.9 0.7 2.6 2 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 3e-13 50.1 1.4 2.6e-12 47.0 0.4 2.1 2 WD40_WDHD1_1st WDHD1 first WD40 domain 6.7e-12 46.0 0.1 3.2e-05 24.2 0.1 2.4 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 2.8e-10 40.2 0.0 6e-10 39.1 0.0 1.5 1 WD40_Prp19 Prp19 WD40 domain 4.8e-09 36.5 0.0 9.2e-09 35.6 0.0 1.5 1 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 6.6e-09 36.4 12.3 0.0012 19.8 0.2 5.9 6 WD40 WD domain, G-beta repeat 1.3e-08 35.0 0.4 2.2e-07 31.0 0.0 2.7 3 Beta-prop_EML_2 Echinoderm microtubule-associated 6.1e-07 29.4 0.0 0.0049 16.6 0.0 2.5 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 8.3e-07 28.9 3.9 0.0001 22.1 0.4 3.1 3 Beta-prop_Aladin Aladin seven-bladed propeller 7.3e-06 25.7 0.0 2e-05 24.2 0.0 1.7 2 MIOS_WD40 MIOS, WD40 repeat 1.6e-05 24.6 0.0 0.0011 18.6 0.0 2.5 2 WDR55 WDR55 1.7e-05 24.6 0.0 2.7e-05 23.9 0.0 1.4 1 EIF3I EIF3I 6.7e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 8.7e-05 23.2 0.1 0.23 12.2 0.0 4.0 4 ANAPC4_WD40 Anaphase-promoting complex subunit 9e-05 22.4 0.3 0.0033 17.2 0.0 2.0 2 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 0.00013 21.6 1.0 0.0025 17.3 0.0 2.3 2 WD40_Gbeta G protein beta WD-40 repeat protei 0.00033 20.3 0.1 0.0013 18.3 0.0 1.7 1 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.00036 20.5 0.8 3.1 7.6 0.1 3.7 4 Beta-prop_RIG_2nd RIG second beta-propeller 0.00088 19.2 0.0 0.0018 18.1 0.0 1.6 1 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 0.0015 18.1 1.6 0.044 13.2 0.0 2.4 2 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 0.0018 18.1 0.0 0.004 17.0 0.0 1.5 1 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller ------ inclusion threshold ------ 0.012 15.5 0.1 0.17 11.8 0.0 2.6 3 Beta-prop_EIPR1 EIPR1 beta-propeller 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 0.044 14.3 1.0 0.082 13.4 0.0 2.0 1 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 0.076 12.4 0.0 1.1 8.6 0.0 2.3 1 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain Domain annotation for each model (and alignments): >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.14 1.3e+02 247 268 .. 68 89 .. 60 95 .. 0.73 2 ! 53.0 0.1 3.7e-17 3.5e-14 3 145 .. 76 228 .. 74 228 .. 0.86 3 ! 39.5 0.0 4.7e-13 4.5e-10 51 198 .. 174 323 .. 168 326 .. 0.82 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.14 Beta-prop_THOC3 247 svhtikteaavnsvawhPskkl 268 +v+ + + ++v s+aw+P+ ++ FUN_001407-T1 68 HVTDFHHGTNVLSLAWSPKTNI 89 4555666677778888887765 PP == domain 2 score: 53.0 bits; conditional E-value: 3.7e-17 Beta-prop_THOC3 3 kkvhsvawsadGk........rLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktk 88 ++v s+aws++ + + +++D+ +r + + +++s+ l+gh + ++ ++p + +a++s+D+t rlWd++tgk+ + + ++ FUN_001407-T1 76 TNVLSLAWSPKTNiqhlpyslQFGMAGEDNKIRYFVSDARNSSSVIILEGHLNYINDCIIEPVSGMEVASVSDDHTCRLWDLETGKQKSCIPLS 169 566666666665422222222467799**********9999999999*********************************************** PP Beta-prop_THOC3 89 geninlawsp.dGktiavgskddtvslidvrtgk.vkkeekfkkevnevafspdgklll 145 + ++++w+ + + ++v++k+ +++++d+ +++ + + ++ + + +s++++ll+ FUN_001407-T1 170 SAGVSVKWHRkEPNKLMVAQKNGLIRFYDLLSQQpIMSLSTGQVPLMSADWSSTNDLLV 228 ********97479****************9998725667778999*********99986 PP == domain 3 score: 39.5 bits; conditional E-value: 4.7e-13 Beta-prop_THOC3 51 qlawspthpdllatassDktvrlWdvrtgkstatvktkgeni.nlawspdGktiavgskddtvslidvrtgkv..kkeekfkkevnevafspdg 141 +++w+ ++p+ l+ a + +r++d+ +++++ +++t + + + ws ++ + d ++d+++ + e+ + + v ++++s+ + FUN_001407-T1 174 SVKWHRKEPNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLmSADWSSTNDLLVGAVARDDWIIWDMSKSSLpaCIEQAHPDGVCKFRWSNVQ 267 79**********************************9887752799***999999988999999******986325688899************ PP Beta-prop_THOC3 142 kllllttgdg..tvevlsypsleevktlkahtsnclcvafdpkgrylAvGsaDalvslW 198 + l++ttg +v+++++ + + ++ s+ ++++p+ + A+G+ ++ v+lW FUN_001407-T1 268 DSLFATTGRPgnHVNIYHMDHHKIPVSC--QMSTGGGLSWHPSLPICASGGGNK-VHLW 323 ******9975115666666665555555..555555778899999999999765.5777 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.8 4.2e-18 4e-15 47 291 .. 74 323 .. 63 324 .. 0.84 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 4.2e-18 Beta-prop_WDR5 47 hkkGisdvawssd........skllasaSDDktvriw..dvetgkllktlkgHtnyvfcvaFnpkgnl.lvSGsfDetvrlWdvrtgkclktlpa 130 h + + ++aws++ s a +D+++r + d+++++ + +l+gH ny+ + +p + + ++S s D+t rlWd++tgk ++p FUN_001407-T1 74 HGTNVLSLAWSPKtniqhlpySLQFGMAGEDNKIRYFvsDARNSSSVIILEGHLNYINDCIIEPVSGMeVASVSDDHTCRLWDLETGKQKSCIPL 168 45556667777764443444355778899******873356677899***********9999997655499************************ PP Beta-prop_WDR5 131 HsdpvsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvsfvkFspngkyiLastldstirLwdyekekvvktYkghknekycisa 225 s vs ++ + ++ + +glir +d + q + +l + p++++ +s ++ ++ + + +wd++k+ + + + + c + FUN_001407-T1 169 SSAGVSVKWHRKEPNKLMVAQKNGLIRFYDLLSQQPIMSLS-TGQVPLMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPACIEQAHPDGVCKFR 262 *****9888888999*************************7.6799********9999999999999999******9988888888888888877 PP Beta-prop_WDR5 226 efsetggklvvsGsedgkvyiwdlqskeivqkleghkdvvlavdchpteniiasgslekdktvkiw 291 ++++ + +G ++v i+++ +++i + + ++ ++ hp+ +i asg+ ++v++w FUN_001407-T1 263 WSNVQDSLFATTGRPGNHVNIYHMDHHKIPVSCQMSTG--GGLSWHPSLPICASGGG---NKVHLW 323 77777789999******************988876655..56678999999999998...668877 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.1 0.00052 0.49 213 292 .] 67 155 .. 8 155 .. 0.71 2 ! 49.9 0.7 4e-16 3.8e-13 22 200 .. 143 319 .. 130 326 .. 0.82 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00052 WD40_CDC20-Fz 213 kllksvdtgsqvtsllwskee..kelvsthgys....knqivlw..kypslkkvaeleghtervlslalsp.dgetvvtasaDetlrfW 292 + +++++ g++v sl+ws+++ + l + + +n+i+ + ++ + + v legh + + + p +g v+++s D+t r+W FUN_001407-T1 67 QHVTDFHHGTNVLSLAWSPKTniQHLPYSLQFGmageDNKIRYFvsDARNSSSVIILEGHLNYINDCIIEPvSGMEVASVSDDHTCRLW 155 57888999999*******977335777777774333367777552166778889999**********999945678999********99 PP == domain 2 score: 49.9 bits; conditional E-value: 4e-16 WD40_CDC20-Fz 22 vlavalgssvylwnaetgevkelldlseesdyvtsvkws.edgelLavGtssgevelwdvekkkklrtleghssrvgalawnenl.lssGs.rdgk 114 v +v ++++ lw+ etg+ k+++ ls + svkw ++ + L+v++++g ++++d +++ + +l++ + + +w++++ l++G FUN_001407-T1 143 VASVSDDHTCRLWDLETGKQKSCIPLS---SAGVSVKWHrKEPNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTNdLLVGAvARDD 235 55677788999*********9999886...6789****945679*************************************765557777625678 PP WD40_CDC20-Fz 115 ilhhDvrtkelevvktlkahkqevcglkwsp..dgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGta 200 +++D+ +++l +++ +ah + vc +ws+ d+ + ++G n v+i+++++ + +++ ++ l+W+p + + a+GGG++ FUN_001407-T1 236 WIIWDMSKSSLP-ACIEQAHPDGVCKFRWSNvqDSLFATTGRPGNHVNIYHMDHHKIPVSCQ--MSTGGGLSWHPSLP-ICASGGGNK 319 899*****9986.6899*************94334445677789********9988555544..577889*****775.88****974 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.2 1.9e+02 262 278 .. 72 88 .. 63 95 .. 0.73 2 ! 47.0 0.4 2.7e-15 2.6e-12 103 283 .. 100 273 .. 95 279 .. 0.88 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.2 WD40_WDHD1_1st 262 hekklaitslaWnpken 278 ++ +++ slaW+pk+n FUN_001407-T1 72 FHHGTNVLSLAWSPKTN 88 34567899999999876 PP == domain 2 score: 47.0 bits; conditional E-value: 2.7e-15 WD40_WDHD1_1st 103 agseDftik..vvsvedsskqktleghkapvlsvaldpkg.eylaSsscDGtvkiWdieskecvktlkvlpksndfsaskslcrlawepksgkll 194 +++eD +i+ v + ++ss++ legh + + + ++p + +aS s D t ++Wd+e++++++++ + s+ ++w+ k+ + l FUN_001407-T1 100 MAGEDNKIRyfVSDARNSSSVIILEGHLNYINDCIIEPVSgMEVASVSDDHTCRLWDLETGKQKSCIPL---SS------AGVSVKWHRKEPNKL 185 6899****94445679999*******************762569*****************99987554...33......345689********* PP WD40_WDHD1_1st 195 avPveke.vklyerdtweeafklsknklsedisivafSpcGkylaaatvdgeilvWdvatkeliervkhekklaitslaWnpkeneLaft 283 +v++++ +++y+ + + +++ls+ ++ + + +S++ + l+ a ++++Wd+++ +l +++++ + +++ W+ +++L+ t FUN_001407-T1 186 MVAQKNGlIRFYDLLSQQPIMSLSTGQVP--LMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPACIEQAHPDGVCKFRWSNVQDSLFAT 273 ***999659****************9995..6779***********************************************99988765 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.1 3.4e-08 3.2e-05 89 147 .. 101 162 .. 67 177 .. 0.79 2 ! 19.6 0.0 8.8e-07 0.00083 38 128 .. 179 270 .. 163 289 .. 0.84 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 3.4e-08 Beta-prop_WDR3_1st 89 GskDtdi..ivwDvvaeaglfrLkgHkdqvtsvafleek.kvlvssSkDtliklWdletqhc 147 +++D++i v D + + ++ L+gH + ++++ + + + ++s S+D++ +lWdlet+++ FUN_001407-T1 101 AGEDNKIryFVSDARNSSSVIILEGHLNYINDCIIEPVSgMEVASVSDDHTCRLWDLETGKQ 162 56777773358899999999999999999999999875515589999999999999999876 PP == domain 2 score: 19.6 bits; conditional E-value: 8.8e-07 Beta-prop_WDR3_1st 38 spdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrL.kgHkdqvtsvafleekkv 127 ++ +kl v+ ++g ir +dl s++ ++++ + ++ ++++++ L+ + + d i+wD+ + + + + H d v + ++++ ++ FUN_001407-T1 179 RKEPNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPACIeQAHPDGVCKFRWSNVQDS 269 45568899*******************************************************9988755541578888888888876655 PP Beta-prop_WDR3_1st 128 l 128 l FUN_001407-T1 270 L 270 5 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 0.0 6.4e-13 6e-10 48 257 .. 74 296 .. 63 318 .. 0.77 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 6.4e-13 WD40_Prp19 48 htkkvtavafhpsedv........lvsasaDktvrvwkkeek..etaatlkkhkaevtslsvhptgdy.lvsaskDgtwalhdletgktllkvkde 132 h +v ++a++p++++ + a++D+++r + +++ + + +l+ h + +++ + p++ + ++s+s+D t+ l+dletgk+ + FUN_001407-T1 74 HGTNVLSLAWSPKTNIqhlpyslqFGMAGEDNKIRYFVSDARnsSSVIILEGHLNYINDCIIEPVSGMeVASVSDDHTCRLWDLETGKQKSCIPLS 169 677899999999888555555554667999*****99665441267778999***********976542889999***********9998888777 PP WD40_Prp19 133 eskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsasedgtvklWDLRklknfktleldeeskvnsvaF 228 +++ +++ + P+ l++ ++k+g ++++D+ sq+ ++sl+ + ++ s + S L+ a + +WD+ k++ + +e + v + ++ FUN_001407-T1 170 SAGVSVKWHRKEPNKLMV--AQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPACIEQAHPDGVCKFRW 263 777777777777888776..7899*****************999999999999876666666655558889*****99999999998889999999 PP WD40_Prp19 229 DksgqyL.ava...gsdvrvyevkkweelatle 257 + + L a++ g++v++y++ + + ++++ FUN_001407-T1 264 SNVQDSLfATTgrpGNHVNIYHMDHHKIPVSCQ 296 887766634432556789999887776666655 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.6 0.0 9.7e-12 9.2e-09 48 266 .] 69 287 .. 56 287 .. 0.77 Alignments for each domain: == domain 1 score: 35.6 bits; conditional E-value: 9.7e-12 Beta-prop_WDR36-Utp21_1st 48 ivvfkrgkevaellkeheekikkllvfgdhlvavdednsllvwkieteelyteiefsee.efeitallhpsTYlnKilvgskqG 130 + f++g++v +l + +++i++l ++ ++ edn+++++ ++ ++ + i ++ + + +++ p ++ + +s++ FUN_001407-T1 69 VTDFHHGTNVLSLAWSPKTNIQHLPYSLQFG-MAGEDNKIRYFVSDARNSSSVIILEGHlNYINDCIIEPVSGME-VASVSDDH 150 5666677777666666667776654444443.3445566666666666666666666551333445555555554.55556666 PP Beta-prop_WDR36-Utp21_1st 131 slqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsss 214 + +lw+++tgk ++ +++ +++ + + + ++ ++G i ++++ + +++l++ + p s + + +l+ + + FUN_001407-T1 151 TCRLWDLETGKQKSCIPLSSAGVSVKWHRKEPNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSST-NDLLVGAVAR 233 99**************99999999999999999****************************999999998875.77999999** PP Beta-prop_WDR36-Utp21_1st 215 GdialwdLekrrlvhvlrnaHeggvtkleflpgqp.llvtsg.aDNslkewifD 266 d ++wd++k++l ++++aH gv k ++ + q l+ t+g N+++++ +D FUN_001407-T1 234 DDWIIWDMSKSSLPACIEQAHPDGVCKFRWSNVQDsLFATTGrPGNHVNIYHMD 287 ********************************9872556777567888877766 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.011 11 9 26 .. 73 98 .. 65 110 .. 0.64 2 ! 19.8 0.2 1.2e-06 0.0012 3 39 .] 119 156 .. 117 156 .. 0.88 3 ? -1.2 0.0 5.8 5.5e+03 14 39 .] 173 198 .. 164 198 .. 0.74 4 ? 3.5 0.1 0.18 1.7e+02 12 32 .. 213 234 .. 202 240 .. 0.65 5 ? 0.1 0.0 2.1 2e+03 8 27 .. 252 271 .. 247 285 .. 0.74 6 ! 8.2 0.6 0.0059 5.5 16 38 .. 302 323 .. 280 323 .. 0.86 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.011 WD40 9 gHtsgVtslafspdgsl........l 26 H ++V sla+sp ++ + FUN_001407-T1 73 HHGTNVLSLAWSPKTNIqhlpyslqF 98 57666********9887665555552 PP == domain 2 score: 19.8 bits; conditional E-value: 1.2e-06 WD40 3 llrtlkgHtsgVtslafspdgsl.lasgsdDgtvklWd 39 ++ +l+gH + ++++ + p + + +as sdD+t++lWd FUN_001407-T1 119 SVIILEGHLNYINDCIIEPVSGMeVASVSDDHTCRLWD 156 56789***999****9888888879999*********9 PP == domain 3 score: -1.2 bits; conditional E-value: 5.8 WD40 14 Vtslafspdgsl.lasgsdDgtvklWd 39 V s++++ + l ++ ++g ++++d FUN_001407-T1 173 V-SVKWHRKEPNkLMVAQKNGLIRFYD 198 5.7777776666666788889999987 PP == domain 4 score: 3.5 bits; conditional E-value: 0.18 WD40 12 sgVtslafspdgsllasg.sdD 32 + +s ++s++++ll+ + ++D FUN_001407-T1 213 VPLMSADWSSTNDLLVGAvARD 234 557999*********8334444 PP == domain 5 score: 0.1 bits; conditional E-value: 2.1 WD40 8 kgHtsgVtslafspdgslla 27 ++H +gV+ ++s + l+ FUN_001407-T1 252 QAHPDGVCKFRWSNVQDSLF 271 48999999999887666654 PP == domain 6 score: 8.2 bits; conditional E-value: 0.0059 WD40 16 slafspdgsllasgsdDgtvklW 38 +l+++p+ ++ asg+ ++v+lW FUN_001407-T1 302 GLSWHPSLPICASGG-GNKVHLW 323 477************.******* PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 2.1 1.9e+03 91 110 .. 93 112 .. 63 133 .. 0.53 2 ! 31.0 0.0 2.4e-10 2.2e-07 12 143 .. 142 274 .. 135 290 .. 0.89 3 ? 0.2 0.0 0.6 5.6e+02 3 25 .. 302 323 .. 300 326 .. 0.84 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2.1 Beta-prop_EML_2 91 pdgklLavgshdnkiylYdv 110 p + ++ +dnki + FUN_001407-T1 93 PYSLQFGMAGEDNKIRYFVS 112 33333444455555554443 PP == domain 2 score: 31.0 bits; conditional E-value: 2.4e-10 Beta-prop_EML_2 12 qfvTagdDktvrlWdlekkklvakvklekearsvafspdg.kllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnk 104 ++++++dD+t rlWdle+ k+ ++ l+++ sv+++ ++ + l+v+ k+G + +d + + ++++++ + ++ +s+ ++lL+ + + FUN_001407-T1 142 EVASVSDDHTCRLWDLETGKQKSCIPLSSAGVSVKWHRKEpNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTNDLLVGAVARDD 235 6899*********************************665279*******************************************98877666 PP Beta-prop_EML_2 105 iylYdvskkykkvgklkghssfithlDwsedskylqsns 143 ++d+sk+ + + h + + ++ ws+ + l ++ FUN_001407-T1 236 WIIWDMSKSSLPACIEQAHPDGVCKFRWSNVQDSLFATT 274 7799*9999999999999999999999998776665555 PP == domain 3 score: 0.2 bits; conditional E-value: 0.6 Beta-prop_EML_2 3 GLathpsepqfvTagdDktvrlW 25 GL+ hps p+++++g + v lW FUN_001407-T1 302 GLSWHPSLPICASGGG-NKVHLW 323 89*******9999887.667888 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.85 8.1e+02 113 146 .. 55 88 .. 20 91 .. 0.69 2 ! 16.6 0.0 5.2e-06 0.0049 216 287 .. 74 156 .. 64 163 .. 0.76 3 ! 10.4 0.0 0.00041 0.39 148 235 .. 185 273 .. 161 298 .. 0.82 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.85 Beta-prop_WDR3_2nd 113 eeeeskakklslkhtrtlklsddvlcvkvspdkk 146 e +es+ l+++h+ ++ +vl++ sp+++ FUN_001407-T1 55 EASESHLPALQFQHVTDFHHGTNVLSLAWSPKTN 88 2235677899999999999999999999999865 PP == domain 2 score: 16.6 bits; conditional E-value: 5.2e-06 Beta-prop_WDR3_2nd 216 hddsvmsvafvpkt........HylfsagkdkkvkyW..Dadkfekiqtleghagevwalavss.kgkfvvsashDksiRlwe 287 h +v+s+a+ pkt ++ ag d+k++y+ Da + ++++ legh + + + +g+ v+s+s D++ Rlw+ FUN_001407-T1 74 HGTNVLSLAWSPKTniqhlpysLQFGMAGEDNKIRYFvsDARNSSSVIILEGHLNYINDCIIEPvSGMEVASVSDDHTCRLWD 156 55556666666655444111115666799*******877999999************988876527999*************7 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00041 Beta-prop_WDR3_2nd 148 lavallDstvkvfflDtlkfflslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchksl.fahddsvmsvafvpktHylfsa 235 l+va + ++ + l + + ++sl ++P++s d ss + l+v + a + iw + + + ah d v + ++ + lf++ FUN_001407-T1 185 LMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPACIeQAHPDGVCKFRWSNVQDSLFAT 273 55555566666666667788999*99********************9999999****999999999789*****999999988888764 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.16 1.5e+02 312 338 .. 63 93 .. 46 95 .. 0.57 2 ? 4.5 0.0 0.023 22 118 181 .. 135 198 .. 105 203 .. 0.65 3 ! 22.1 0.4 1.1e-07 0.0001 108 173 .. 210 275 .. 199 292 .. 0.84 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.16 Beta-prop_Aladin 312 lisFqp..nfekg.alLtvvws.sgrvqyvP 338 ++Fq+ +f++g ++L+++ws + ++q++P FUN_001407-T1 63 ALQFQHvtDFHHGtNVLSLAWSpKTNIQHLP 93 4566542245544257777777446677777 PP == domain 2 score: 4.5 bits; conditional E-value: 0.023 Beta-prop_Aladin 118 WspkGdlLvsaspvdtsilvWdvak...etavpLrrvggggvsllkwsp.dgskllaatpssvfrvwe 181 +p + v++ d + +Wd ++ ++++pL+ +g vs +kw + +kl++a ++ + r ++ FUN_001407-T1 135 IEPVSGMEVASVSDDHTCRLWDLETgkqKSCIPLSSAG---VS-VKWHRkEPNKLMVAQKNGLIRFYD 198 45544455555567889999**9862226788887754...44.566651568999999998888876 PP == domain 3 score: 22.1 bits; conditional E-value: 1.1e-07 Beta-prop_Aladin 108 pghspvtsvaWspkGdlLvsaspvdtsilvWdvaketa.vpLrrvggggvsllkwspdgskllaatp 173 +g p++s Ws + dlLv a + d ++Wd++k++ ++++ gv+ +ws ++ l+a+t FUN_001407-T1 210 TGQVPLMSADWSSTNDLLVGAVARDD-WIIWDMSKSSLpACIEQAHPDGVCKFRWSNVQDSLFATTG 275 5689****************999986.679***99886256899999*****************995 PP >> MIOS_WD40 MIOS, WD40 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.48 4.5e+02 171 214 .. 113 159 .. 63 199 .. 0.55 2 ! 24.2 0.0 2.1e-08 2e-05 141 265 .. 167 294 .. 104 300 .. 0.79 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.48 MIOS_WD40 171 dlrntsqkmfvnt..kavqgvtvdpyfhdrvasfyegq.vaiwdlrk 214 d rn+s ++++ + ++ ++p vas+ + + +wdl FUN_001407-T1 113 DARNSSSVIILEGhlNYINDCIIEPVSGMEVASVSDDHtCRLWDLET 159 55555555554431133455555555555555554433134555543 PP == domain 2 score: 24.2 bits; conditional E-value: 2.1e-08 MIOS_WD40 141 gqndaclslcwlprd.qklllagmhrnlaifdlrntsqkmfvntkavqgvtvdpyfhd..rvasfyegqvaiwdlrkfekpvltlteqpkpltkva 233 a +s+ w ++ +kl++a + +dl m + t v ++ d + v ++ + iwd+ k p +p + k FUN_001407-T1 167 PLSSAGVSVKWHRKEpNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTNdlLVGAVARDDWIIWDMSKSSLPACIEQAHPDGVCKFR 262 455677889998876367888888778889999999999999***99999999765431247788899999************99999******** PP MIOS_WD40 234 wcptrtgllatltrdsniirlydmqhtptpig 265 w + l+at r n + +y m+h p+ FUN_001407-T1 263 WSNVQDSLFATTGRPGNHVNIYHMDHHKIPVS 294 ***************************99986 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.0 1.1e-06 0.0011 49 135 .. 123 210 .. 69 228 .. 0.82 2 ? 3.5 0.0 0.045 43 68 124 .. 227 286 .. 210 299 .. 0.70 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 1.1e-06 WDR55 49 lehhkkscraveFse.dGkklfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdddGtvklWDlRkkkavmelke 135 le h + + + + +G ++ svs D+++++ d+etgk k++i + + + + n l+ ++ +G ++++Dl +++++m+l+ FUN_001407-T1 123 LEGHLNYINDCIIEPvSGMEVASVSDDHTCRLWDLETGKQKSCIPLSSAGVSVKWHRKEPNKLMVAQKNGLIRFYDLLSQQPIMSLST 210 5555555555554432899**************************99999889999999*************************9976 PP == domain 2 score: 3.5 bits; conditional E-value: 0.045 WDR55 68 lfsvskDksiavldvetgklkkkiekahespiysl..lvidenllat.GdddGtvklWDl 124 l+ + + + d+++++l +ie+ah + + ++ + +++ l+at G +v+++ + FUN_001407-T1 227 LVGAVARDDWIIWDMSKSSLPACIEQAHPDGVCKFrwSNVQDSLFATtGRPGNHVNIYHM 286 5555555567789****************9998762245667777751555556666655 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 2.9e-08 2.7e-05 48 199 .. 123 266 .. 98 292 .. 0.81 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 2.9e-08 EIF3I 48 yeGheGavwsidvdset.tllvtgsadntvklWdvetGkelktletktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlki 142 +eGh + ++ ++ + +++ s d+t++lWd+etGk+ + + ++a sv++ ++ + l+v++ k++ i+++d+ + ++p++++ FUN_001407-T1 123 LEGHLNYINDCIIEPVSgMEVASVSDDHTCRLWDLETGKQKSCIPLSSAGVSVKWHRKEPNKLMVAQ----KNGLIRFYDLLS------QQPIMSL 208 67888888777777655156889999*****************************999988887765....578999999854......6799*** PP EIF3I 143 eveeskvtvalwsaldktiitghedgeiskydlktgeklks.vkehekqitdlqlskd 199 ++ + +++a ws++++ ++ + ++ + +d+++++ + +++h + + +++s+ FUN_001407-T1 209 STGQVPLMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPACiEQAHPDGVCKFRWSNV 266 *********************************9988766514567777777777654 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 1.2e-07 0.00011 8 110 .. 142 244 .. 136 261 .. 0.87 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.2e-07 Beta-prop_WDR90_POC16_2nd 8 qlatvseDetiriWdldtlqqlydfsaseeaPcavafhPskq.vfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdg 90 ++a vs+D+t r+Wdl+t +q + + a ++v +h +++ ++ ++G++r++++ + + ++ ++ + +++ s+++ FUN_001407-T1 142 EVASVSDDHTCRLWDLETGKQKSCI-PLSSAGVSVKWHRKEPnKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTN 224 689******************8655.578899******9885269999*****************9999999999999999999 PP Beta-prop_WDR90_POC16_2nd 91 eylysacslGslalydasee 110 ++l a ++ ++d+s++ FUN_001407-T1 225 DLLVGAVARDDWIIWDMSKS 244 99999988888888887766 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.33 3.1e+02 25 51 .. 65 88 .. 52 96 .. 0.80 2 ? 3.4 0.0 0.14 1.3e+02 53 89 .. 143 178 .. 138 180 .. 0.81 3 ! 12.2 0.0 0.00024 0.23 43 90 .. 174 222 .. 152 223 .. 0.77 4 ? 5.0 0.1 0.043 41 2 80 .. 219 299 .. 218 308 .. 0.79 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.33 ANAPC4_WD40 25 nwqrvwklseekedsevtslaWkpdGk 51 ++q v ++ +++ +v slaW+p+ + FUN_001407-T1 65 QFQHVTDF---HHGTNVLSLAWSPKTN 88 56666666...89999*******9866 PP == domain 2 score: 3.4 bits; conditional E-value: 0.14 ANAPC4_WD40 53 LavaysdgevrlldvesgklvhslsaksdkitcleWa 89 a + +d ++rl d e+gk + ++ +s ++++W FUN_001407-T1 143 VASVSDDHTCRLWDLETGKQKSCIPLSSA-GVSVKWH 178 56677899***********9999999888.6667775 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00024 ANAPC4_WD40 43 slaWkpdG.klLavaysdgevrlldvesgklvhslsaksdkitcleWae 90 s++W+ ++ + L+va ++g +r++d s + + sls+++ ++ +W++ FUN_001407-T1 174 SVKWHRKEpNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSS 222 89999877578***************************99888888876 PP == domain 4 score: 5.0 bits; conditional E-value: 0.043 ANAPC4_WD40 2 swcpkmDLiAlatedgevllkRlnwqrvwklseekedsevtslaWkp.dGklLavaysdg.evrlldvesgklvhslsaks 80 w++++DL++ a ++ + ++ ++ + e+++ v +++W++ + l+a g +v+++++ k+ s+++++ FUN_001407-T1 219 DWSSTNDLLVGAVARDDWIIWDMSKSSLPACIEQAHPDGVCKFRWSNvQDSLFATTGRPGnHVNIYHMDHHKIPVSCQMST 299 699999*9999999999999999999999999999999999****872445555544444499999999999888777665 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 3.4e-06 0.0033 214 288 .. 99 176 .. 56 181 .. 0.76 2 ? 2.5 0.1 0.1 98 255 300 .. 185 231 .. 177 247 .. 0.67 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 3.4e-06 Beta-prop_WDR36-Utp21_2nd 214 avalddfsil..vvDidtrrvvRkfsghknritDltfspda.rWlitasmDstirtwdlpsgkliDvflvesaatsls 288 +a +d +i+ v D + v ++gh n i+D ++ p + + + s D t r wdl +gk + ++sa +s++ FUN_001407-T1 99 GMAGEDNKIRyfVSDARNSSSVIILEGHLNYINDCIIEPVSgMEVASVSDDHTCRLWDLETGKQKSCIPLSSAGVSVK 176 56666666652267888889999**************99661557778999*******************99999997 PP == domain 2 score: 2.5 bits; conditional E-value: 0.1 Beta-prop_WDR36-Utp21_2nd 255 litasmDstirtwdlpsgkliDvflves.aatslslsptgdfLatah 300 l+ a ir +dl s + i +++ + + +s + s+t+d+L+ a FUN_001407-T1 185 LMVAQKNGLIRFYDLLSQQPIMSLSTGQvPLMSADWSSTNDLLVGAV 231 55666677788888888777777776541457888888888877654 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 2.6e-06 0.0025 137 180 .. 121 166 .. 93 188 .. 0.76 2 ? 2.1 0.1 0.11 1.1e+02 59 301 .. 216 243 .. 173 285 .. 0.66 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.6e-06 WD40_Gbeta 137 relaghtgylsccrf..lddnqivtssgdttcalwdietgqqttvf 180 l gh y+ c + + ++ + s d tc lwd+etg+q++++ FUN_001407-T1 121 IILEGHLNYINDCIIepVSGMEVASVSDDHTCRLWDLETGKQKSCI 166 3578999999888663356778888899999999999999999765 PP == domain 2 score: 2.1 bits; conditional E-value: 0.11 WD40_Gbeta 59 yamhwgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnfvacggldnicsiynlktregnvrvsrelaghtgylsccrfldd 154 + w++ llv a iiwd FUN_001407-T1 216 MSADWSSTNDLLVGAVARDDWIIWD----------------------------------------------------------------------- 240 3334555555555555555555555....................................................................... PP WD40_Gbeta 155 nqivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsddatc 250 FUN_001407-T1 - ------------------------------------------------------------------------------------------------ - ................................................................................................ PP WD40_Gbeta 251 rlfdlradqellvyshdniicgitsvafsksgrlllagyddfncnvwdalk 301 k FUN_001407-T1 241 ------------------------------------------------MSK 243 ................................................444 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 1.4e-06 0.0013 2 118 .. 174 293 .. 173 299 .. 0.77 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.4e-06 Beta-prop_WDR19_1st 2 lfaWqkksgnylavagknkvvkiydrqGelvdeiklkg..kctaleWdkdgdlLaiiqeksslvllwdantkkt.skldtglkdkltfll 88 ++W++k+ n l va+kn +++ yd ++ +g ++ +W++++dlL + + ++wd+++++ ++ d ++ ++ FUN_001407-T1 174 SVKWHRKEPNKLMVAQKNGLIRFYDLLSQQPIMSLSTGqvPLMSADWSSTNDLLVGAVARDD-WIIWDMSKSSLpACIEQAHPDGVCKFR 262 689**********************988765444444401568889*******976666555.568**9998874689************ PP Beta-prop_WDR19_1st 89 WskkspiLavGtsk.Gn.lllYnkktskkipi 118 Ws+ ++ L +t + Gn + +Y + + kip+ FUN_001407-T1 263 WSNVQDSLFATTGRpGNhVNIY-HMDHHKIPV 293 ****999977765448834455.566677887 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.0 0.0068 6.5 30 55 .. 68 95 .. 47 105 .. 0.72 2 ? 2.1 0.0 0.15 1.5e+02 222 251 .. 135 164 .. 97 173 .. 0.74 3 ! 7.6 0.1 0.0033 3.1 167 271 .. 129 226 .. 114 233 .. 0.73 4 ? 1.3 0.0 0.27 2.5e+02 208 237 .. 249 278 .. 237 300 .. 0.68 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0068 Beta-prop_RIG_2nd 30 sieslkvkskvlsLaWspdken..LAfg 55 +++ ++ ++vlsLaWsp+ + L ++ FUN_001407-T1 68 HVTDFHHGTNVLSLAWSPKTNIqhLPYS 95 455666779*********6543237776 PP == domain 2 score: 2.1 bits; conditional E-value: 0.15 Beta-prop_RIG_2nd 222 wsnansnlllsfsidgkvkvWdleepekee 251 + + ++ s+s d + ++Wdle+++++ FUN_001407-T1 135 IEPVSGMEVASVSDDHTCRLWDLETGKQKS 164 555556677888889999999999999865 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0033 Beta-prop_RIG_2nd 167 yitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekeeltitykc 258 yi+d ++p++ +A v+ d++ ++++ k+ + + + svkw +++ n l+ + +g ++ +dl +++ + t + FUN_001407-T1 129 YINDCIIEPVSGMEVASVSDDHTCRLWDLETG-------KQKSCIPLSSAGVSVKWHRKEPNKLMVAQKNGLIRFYDLLSQQPIMSLSTGQV 213 66666666666666666666666666665522.......222223334456799******9999999**********999999888888999 PP Beta-prop_RIG_2nd 259 pmlcglFlPtden 271 p++++ ++ t++ FUN_001407-T1 214 PLMSADWSSTNDL 226 9999999888875 PP == domain 4 score: 1.3 bits; conditional E-value: 0.27 Beta-prop_RIG_2nd 208 itasaekasitsvkwsnansnlllsfsidg 237 ++ +a+ + + +wsn ++ l+ +++ g FUN_001407-T1 249 CIEQAHPDGVCKFRWSNVQDSLFATTGRPG 278 456677778888888888888887776544 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.0 1.9e-06 0.0018 22 68 .. 114 160 .. 93 189 .. 0.82 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 1.9e-06 Beta-prop_WDR75_1st 22 tsteecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdg 68 ++ +v l+gh + + +++p ++v s s d t rlwd g FUN_001407-T1 114 ARNSSSVIILEGHLNYINDCIIEPVSGMEVASVSDDHTCRLWDLETG 160 334567999**********************************8765 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 4.7e-05 0.044 151 211 .. 104 167 .. 66 208 .. 0.68 2 ? 3.3 0.3 0.049 46 138 181 .. 220 264 .. 215 299 .. 0.66 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 4.7e-05 Beta-prop_CAF1B_HIR1 151 Dnta..ilWdvekgkklailkdhkgfvqgvawdPkn.qyvatlssDrslrifdiktkkvvarvs 211 Dn++ + d ++++++ il+ h +++ ++P + va++s D ++r++d++t k + + FUN_001407-T1 104 DNKIryFVSDARNSSSVIILEGHLNYINDCIIEPVSgMEVASVSDDHTCRLWDLETGKQKSCIP 167 5654225678888888999999999999999999751558899999999999988877665554 PP == domain 2 score: 3.3 bits; conditional E-value: 0.049 Beta-prop_CAF1B_HIR1 138 wspdskklisgsvDntailWdvekgkklailk.dhkgfvqgvawd 181 ws+++ l+ + + i+Wd++k++ a ++ h + v w FUN_001407-T1 220 WSSTNDLLVGAVARDDWIIWDMSKSSLPACIEqAHPDGVCKFRWS 264 898888888777788999999999987655540455555555555 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 4.2e-06 0.004 62 167 .. 173 275 .. 158 298 .. 0.86 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 4.2e-06 Beta-prop_NUP159_NUP214 62 ihvaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlkarslv.... 143 + v+ + +e + +++a+++g + yd+ s + p++slst +v ++++ ++ +ll+ ++++ ++ d++++sl FUN_001407-T1 173 VSVKWHRKEPNKLMVAQKNGLIRFYDLLSQQ-----PIMSLSTGQVPLMSADWSSTN--DLLVGAVARDDWIIWDMSKSSLPacie 251 579999999999*************998877.....********9999999999995..5888899999************99999 PP Beta-prop_NUP159_NUP214 144 svlkenvssfdwsnkgkqlvvgla 167 + + ++v+ f wsn ++ l++ FUN_001407-T1 252 QAHPDGVCKFRWSNVQDSLFATTG 275 9999**************998754 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.1 0.042 40 220 280 .] 98 155 .. 63 155 .. 0.74 2 ? 11.8 0.0 0.00018 0.17 161 235 .. 130 200 .. 97 228 .. 0.75 3 ? 0.5 0.0 0.48 4.5e+02 161 227 .. 215 278 .. 201 297 .. 0.71 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.042 Beta-prop_EIPR1 220 lltagddgvvlih..DiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 + ag+d + ++ D R + + l++h ++ + + p + s s d+t +Lw FUN_001407-T1 98 FGMAGEDNKIRYFvsDAR-----NSSSVIILEGHLNYINDCIIEPVSGMEVASVSDDHTCRLW 155 455667776665534556.....445567899******************************9 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00018 Beta-prop_EIPR1 161 lrvaAldphdsslvlvace.sglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiR 235 ++ ++p v+ +++ + l+Dl + k+ks + + + +v ++++++nkl+ a ++g + ++D+ FUN_001407-T1 130 INDCIIEPVSGMEVASVSDdHTCRLWDLETGKQKS--CIPLS---SAGVSVKWHRKEPNKLMVAQKNGLIRFYDLL 200 555555665555555555559999****9999999..44433...46789************************96 PP == domain 3 score: 0.5 bits; conditional E-value: 0.48 Beta-prop_EIPR1 161 lrvaAldphdsslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddg 227 l a + + lv +++ + ++D+ + + +e++h + v++ +++++ ++t+g g FUN_001407-T1 215 LMSADWSSTNDLLVGAVARDDWIIWDMSKSSLPA--CIEQAH-PDGVCKFRWSNVQDSLFATTGRPG 278 5566677666777777777888889986544444..777777.666889999999999999999766 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 4.3e-05 0.041 61 134 .. 126 199 .. 107 217 .. 0.87 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 4.3e-05 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsntvvqtYetdspvWsCcWseddsnylyaGlqnGsvlvfDi 134 H + i d ++ + + s+s D+t +l +l++ + + s+ s W+ +++n l + +nG + +D+ FUN_001407-T1 126 HLNYINDCIIEPVSGMEVASVSDDHTCRLWDLETGKQKSCIPLSSAGVSVKWHRKEPNKLMVAQKNGLIRFYDL 199 99999999999999999********************************************************8 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 8.6e-05 0.082 15 70 .. 143 196 .. 135 199 .. 0.81 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 8.6e-05 Beta-prop_TEP1_C 15 iisAseDrtvKlWdretkkqvGlFvCeapvlvlevnpnpeseleLvcgDklGkvYf 70 + s s D+t +lWd et kq +++ ++++ +++++++L+++ k G + f FUN_001407-T1 143 VASVSDDHTCRLWDLETGKQKSCIPLSSAGVSVKW--HRKEPNKLMVAQKNGLIRF 196 6799****************988876666666665..5677899999999998866 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.0012 1.1 23 157 .. 98 237 .. 78 271 .. 0.58 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0012 WD40_MABP1-WDR62_2nd 23 FltcssDdtiRlWnleeksseetal...krniysnellkvlyvdeelsalkdvela....asekkdeseldsknGvRvlkvspdgkhla 104 F +++D+ iR + ++++s++ + + n+ + +++ + e +s+ d+++ ++ k+++ s +Gv v +++ ++l FUN_001407-T1 98 FGMAGEDNKIRYFVSDARNSSSVIIlegHLNYINDCIIEPVSGMEVASVSDDHTCRlwdlETGKQKSCIPLSSAGVSVKWHRKEPNKLM 186 55566666666666666555443321112333333333333222222222222221111123334344445667777777777777777 PP WD40_MABP1-WDR62_2nd 105 sGDrsGniriydletleellkieahdsevlcleyskpetglkllasasRDRli 157 ++G ir ydl +++ ++++ + + +++ ++s+++ l+ + +RD i FUN_001407-T1 187 VAQKNGLIRFYDLLSQQPIMSLSTGQVPLMSADWSSTN--DLLVGAVARDDWI 237 78888888888888888888888777777777777653..3455555666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (327 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 572 (0.0223919); expected 510.9 (0.02) Passed bias filter: 541 (0.0211783); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 27 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.44 # Mc/sec: 3001.56 // Query: FUN_001408-T1 [L=164] Description: FUN_001408 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-20 70.6 0.1 9.5e-20 70.6 0.1 1.8 2 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.2 0.23 6e+03 8 15 .. 53 60 .. 49 63 .. 0.77 2 ! 70.6 0.1 3.7e-24 9.5e-20 3 53 .] 84 134 .. 82 134 .. 0.97 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 0.23 HLH 8 rERrRrdr 15 E+r+r+r FUN_001408-T1 53 PEKRYRER 60 58999976 PP == domain 2 score: 70.6 bits; conditional E-value: 3.7e-24 HLH 3 eahnerERrRrdriNdafdeLrellPtlppdkKlsKaeiLrlAieYIkqLq 53 +++nerER+R++ +Nd+f+ Lr+++P p++kKlsK+e+Lr A+ YIk+Lq FUN_001408-T1 84 ARRNERERNRVRMVNDGFSCLRQHIPYFPDKKKLSKVETLRCAVAYIKHLQ 134 689***********************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1310 (0.0512821); expected 510.9 (0.02) Passed bias filter: 665 (0.0260325); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1604.68 // Query: FUN_001409-T1 [L=134] Description: FUN_001409 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-18 66.6 2.9 3.5e-18 65.6 2.9 1.5 1 HLH Helix-loop-helix DNA-binding domain ------ inclusion threshold ------ 2.5 8.7 5.4 21 5.7 5.4 2.0 1 Peptidase_S49_N Peptidase family S49 N-terminal Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.6 2.9 2.7e-22 3.5e-18 4 53 .] 56 105 .. 54 105 .. 0.97 Alignments for each domain: == domain 1 score: 65.6 bits; conditional E-value: 2.7e-22 HLH 4 ahnerERrRrdriNdafdeLrellPtlppdkKlsKaeiLrlAieYIkqLq 53 ++nerER R++++N+++++Lre+lP p dk++sK+e+Lr Ai+YIk+L+ FUN_001409-T1 56 KRNERERIRVRHVNEGYARLREHLPDEPTDKRMSKVETLRAAIRYIKHLE 105 79**********************************************96 PP >> Peptidase_S49_N Peptidase family S49 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 5.4 0.0016 21 33 70 .. 55 92 .. 49 134 .] 0.85 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0016 Peptidase_S49_N 33 rkkkekgelevtkLneeykelkeeleealldkkelkal 70 rk++e+++++v+++ne y++l+e+l ++ +dk+ k + FUN_001409-T1 55 RKRNERERIRVRHVNEGYARLREHLPDEPTDKRMSKVE 92 78899********************9999998887764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1254 (0.0490898); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1310.59 // Query: FUN_001410-T1 [L=120] Description: FUN_001410 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-05 25.6 4.6 3.7e-05 25.1 4.6 1.3 1 Insulin Insulin/IGF/Relaxin family ------ inclusion threshold ------ 0.017 15.6 10.3 0.026 15.0 0.1 2.6 3 Ins_beta Nematode insulin-related peptide beta type Domain annotation for each model (and alignments): >> Insulin Insulin/IGF/Relaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 4.6 2.9e-09 3.7e-05 3 80 .. 41 118 .. 39 120 .] 0.69 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 2.9e-09 Insulin 3 lCGseLvealylvCge....rgffytapkarrevedplveqledgeeaelkqlgaleesrrkrGiveeCClkpCslkqLesY 80 lCG+++ ++++ Cg+ gf ++ + + e+ + ++le + +++ + + ++ + veeCC+++C+++++++Y FUN_001410-T1 41 LCGDQFKSVWSSCCGHqcgvNGF--KRNLDVKMSEESAKGFLERTWKRD-SFIRNQR-TLHAANAVEECCYEGCTIEEVAEY 118 9*************986654455..445666667777777777444444.3444333.3345568************99876 PP >> Ins_beta Nematode insulin-related peptide beta type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.1 1.6 2e+04 36 39 .. 26 29 .. 24 32 .. 0.57 2 ? 15.0 0.1 2e-06 0.026 15 45 .. 41 66 .. 36 67 .. 0.82 3 ? 6.2 2.1 0.0011 14 30 47 .. 103 120 .] 97 120 .] 0.83 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 1.6 Ins_beta 36 eCtd 39 Ct+ FUN_001410-T1 26 RCTR 29 5665 PP == domain 2 score: 15.0 bits; conditional E-value: 2e-06 Ins_beta 15 vCGeecnvqndvdiatkCCkkeCtdeyIksa 45 +CG+ q ++++++CC +C +++k++ FUN_001410-T1 41 LCGD----QF-KSVWSSCCGHQCGVNGFKRN 66 6777....33.47***************997 PP == domain 3 score: 6.2 bits; conditional E-value: 0.0011 Ins_beta 30 tkCCkkeCtdeyIksacC 47 ++CC + Ct e + + C FUN_001410-T1 103 EECCYEGCTIEEVAEYYC 120 79*******998887777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 875 (0.0342533); expected 510.9 (0.02) Passed bias filter: 473 (0.0185163); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1197.69 // Query: FUN_001411-T1 [L=156] Description: FUN_001411 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-20 72.3 1.7 3e-20 72.3 1.7 1.5 2 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.3 1.5 1 2.6e+04 10 13 .. 50 53 .. 50 55 .. 0.63 2 ! 72.3 1.7 1.2e-24 3e-20 4 53 .] 68 117 .. 66 117 .. 0.98 Alignments for each domain: == domain 1 score: -5.3 bits; conditional E-value: 1 HLH 10 RrRr 13 RrRr FUN_001411-T1 50 RRRR 53 6776 PP == domain 2 score: 72.3 bits; conditional E-value: 1.2e-24 HLH 4 ahnerERrRrdriNdafdeLrellPtlppdkKlsKaeiLrlAieYIkqLq 53 ++n+rER+R++ +Nd+f++Lr+++Pt p++kKlsK+ +Lr AieYI++Lq FUN_001411-T1 68 RRNARERKRVKLVNDGFMRLRKHVPTDPKNKKLSKVKTLRSAIEYIRHLQ 117 79***********************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (156 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1237 (0.0484243); expected 510.9 (0.02) Passed bias filter: 664 (0.0259933); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1558.47 // Query: FUN_001412-T1 [L=134] Description: FUN_001412 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-14 52.1 1.4 1.3e-13 51.6 1.4 1.2 1 Ribosomal_L23 Ribosomal protein L23 ------ inclusion threshold ------ 0.1 12.3 0.1 0.13 12.0 0.1 1.1 1 Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase 0.46 11.2 2.1 0.81 10.4 2.1 1.5 1 Linker_histone linker histone H1 and H5 family Domain annotation for each model (and alignments): >> Ribosomal_L23 Ribosomal protein L23 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.6 1.4 1.5e-17 1.3e-13 20 82 .. 35 101 .. 29 105 .. 0.90 Alignments for each domain: == domain 1 score: 51.6 bits; conditional E-value: 1.5e-17 Ribosomal_L23 20 nkytFeVdkdanKieikkaveklFgVkVekVntlnvkgkkkrvgrk....vgkrsdwKkaiVtLaeg 82 n++ F V+ d++K++ik++++++++V+V kVnt +++gk+k + ++ +k +d+K a+V La+g FUN_001412-T1 35 NTVQFHVPMDMSKLDIKNYLQSIYNVDVYKVNTRIQHGKTKSIVKNdklvKKKLPDYKVAYVVLASG 101 589**************************************76666678778999*********987 PP >> Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 1.5e-05 0.13 78 146 .. 45 112 .. 30 127 .. 0.77 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 1.5e-05 Pyr_redox_3 78 lsgeeaaeYlrevaksfelpiktfeeVesvkk.edegfevetskgtyeakkviiAtGefdkPnklnipGe 146 +s+ ++ +Yl+++ + ++++t + + k+ ++ v+ + +y+ +v++A G f++P++ +p e FUN_001412-T1 45 MSKLDIKNYLQSIYNVDVYKVNTRIQHGKTKSiVKNDKLVKKKLPDYKVAYVVLASGTFKFPDL--FPRE 112 566778899999999888888887766666655556677999999*****************98..4444 PP >> Linker_histone linker histone H1 and H5 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 2.1 9.5e-05 0.81 21 63 .. 45 87 .. 41 106 .. 0.84 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 9.5e-05 Linker_histone 21 sSrqaIkkyikanykvgdvkkfksllkk.aLkkgvekgtlvqpk 63 +S+ Ik+y+++ y+v dv k+++++++ k+ v++++lv+ k FUN_001412-T1 45 MSKLDIKNYLQSIYNV-DVYKVNTRIQHgKTKSIVKNDKLVKKK 87 69999**********9.*****9999873577788888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 669 (0.0261891); expected 510.9 (0.02) Passed bias filter: 481 (0.0188295); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1325.48 // Query: FUN_001413-T1 [L=116] Description: FUN_001413 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0002 22.8 4.6 0.00034 22.0 4.6 1.4 1 Insulin Insulin/IGF/Relaxin family ------ inclusion threshold ------ 0.019 15.7 0.4 0.038 14.7 0.0 1.7 1 Legum_prodom Legumain, prodomain 0.021 14.5 0.1 0.025 14.2 0.1 1.0 1 AC_N Adenylyl cyclase N-terminal extracellular and t 0.11 13.0 5.9 0.8 10.3 2.5 2.2 2 Ins_beta Nematode insulin-related peptide beta type Domain annotation for each model (and alignments): >> Insulin Insulin/IGF/Relaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 4.6 5.3e-08 0.00034 2 81 .] 44 116 .] 43 116 .] 0.66 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 5.3e-08 Insulin 2 hlCGseLvealylvCgergffytapkarrevedplveqledgeeaelkqlgaleesrrkrGiveeCClkpCslkqLesYC 81 ++CG+++ + C ++g ++ +e+++ ++l +++++ +++s + + eeCC ++C +++++YC FUN_001413-T1 44 KYCGDQIMQLFTHYCFNQGRKR-RSVF--LNEQEATSFLLHNTQR----HRRQASSSQATNAWEECCIEGCAHEEVKEYC 116 79*************7755522.1211..2334444555433333....34444455566789***************** PP >> Legum_prodom Legumain, prodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 5.9e-06 0.038 27 64 .. 23 60 .. 11 75 .. 0.86 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 5.9e-06 Legum_prodom 27 eekgsevlksvrpsgqplvddwdClkslvrtfekhCgs 64 + +++++l +v + g++lvd C +++++f ++C++ FUN_001413-T1 23 KGQEPQTLYKVNEVGNSLVDGKYCGDQIMQLFTHYCFN 60 4567899*****************************86 PP >> AC_N Adenylyl cyclase N-terminal extracellular and transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 3.9e-06 0.025 305 384 .. 3 89 .. 1 94 [. 0.82 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 3.9e-06 AC_N 305 raavisgvvlsaihlavslklnaedkfllk.qlvsnvli...fsctnivgvcthypaev..sqrqafqetreciqarlhs.qrenqq 384 ++ + sgv +sai l + l e + l+k + v n l+ ++ +i+ + thy + +r f + +e lh qr +q FUN_001413-T1 3 KSCLWSGVAVSAIFLFIGLTKGQEPQTLYKvNEVGNSLVdgkYCGDQIMQLFTHYCFNQgrKRRSVFLNEQEATSFLLHNtQRHRRQ 89 566789***********************94579***9877789999********976511457789999**999999962555544 PP >> Ins_beta Nematode insulin-related peptide beta type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.01 65 2 17 .. 44 60 .. 43 67 .. 0.85 2 ? 10.3 2.5 0.00012 0.8 23 46 .. 93 116 .] 88 116 .] 0.85 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.01 Ins_beta 2 raCGrrLvkrVlavC.G 17 + CG ++++ + C + FUN_001413-T1 44 KYCGDQIMQLFTHYCfN 60 68********9999944 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00012 Ins_beta 23 qndvdiatkCCkkeCtdeyIksac 46 ++ + +++CC + C e +k+ c FUN_001413-T1 93 SQATNAWEECCIEGCAHEEVKEYC 116 566789**************9988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 866 (0.033901); expected 510.9 (0.02) Passed bias filter: 519 (0.0203171); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1176.36 // Query: FUN_001414-T1 [L=219] Description: FUN_001414 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-20 71.2 1.1 1.2e-19 70.4 1.1 1.5 1 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.4 1.1 4.6e-24 1.2e-19 4 53 .] 93 142 .. 81 142 .. 0.98 Alignments for each domain: == domain 1 score: 70.4 bits; conditional E-value: 4.6e-24 HLH 4 ahnerERrRrdriNdafdeLrellPtlppdkKlsKaeiLrlAieYIkqLq 53 ++nerER+R++ + d+f+ Lr+++Pt+p +kKlsK+e+Lr AieYIk+Lq FUN_001414-T1 93 RRNERERNRVKLVSDGFANLRKHVPTTPTNKKLSKVETLRTAIEYIKHLQ 142 79***********************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1003 (0.039264); expected 510.9 (0.02) Passed bias filter: 651 (0.0254844); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2178.95 // Query: FUN_001415-T1 [L=170] Description: FUN_001415 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-22 79.0 23.5 7.3e-21 75.0 17.6 2.8 2 Tmemb_9 TMEM9 0.0093 16.2 0.3 0.0093 16.2 0.3 1.6 2 SP_C-Propep Surfactant protein C, N terminal propeptide ------ inclusion threshold ------ 0.026 14.8 0.1 0.051 13.8 0.1 1.5 1 Gemini_mov Geminivirus putative movement protein 0.071 13.3 0.0 0.11 12.6 0.0 1.3 1 PH_2nd_LRR Second PH domain in LRR-containing protein 0.34 11.0 2.5 6 6.9 0.1 2.2 2 DUF2207_C Predicted membrane protein (DUF2207) C-terminal 0.37 11.5 2.3 1.2 9.9 0.3 2.2 2 Sigma_reg_N Sigma factor regulator N-terminal 0.59 10.4 3.6 1.3 9.4 3.6 1.5 1 DUF3930 Protein of unknown function (DUF3930) Domain annotation for each model (and alignments): >> Tmemb_9 TMEM9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.5 0.42 1.5e+03 34 55 .. 36 57 .. 7 60 .. 0.73 2 ! 75.0 17.6 2e-24 7.3e-21 3 145 .] 55 169 .. 53 169 .. 0.83 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.42 Tmemb_9 34 fclrCeCkyeeRnttiikvvvi 55 + +C C e t i+ v i FUN_001415-T1 36 VRCKCICPKEGNKTAIVSNVFI 57 4557778888888888776655 PP == domain 2 score: 75.0 bits; conditional E-value: 2e-24 Tmemb_9 3 lyiknvspkkcncegvvlpqlgeevkgkevefclrCeCkyeeRnttiikvvviivisvislLviYmlflvlldpllnkrkkkasyqehnneedess 98 ++i+ v k+cnce +v+ e++fclrC+Ckye+Rnt++ikvv+i++++vi++L++Y++fl + + kr + ++ +e++e+ FUN_001415-T1 55 VFIRAVDAKDCNCEYIVQR---------EEQFCLRCMCKYEARNTSLIKVVIIFILVVIGILCLYLVFLFIDS----KR-RPVELSITADEQQERF 136 678899999****999876.........778**************************************9875....44.5666666666655552 PP Tmemb_9 99 eelssasqslelsarsnvlnrvehqqdkWkrqvkEqrrniydrhtmL 145 + ++ ++++ kWkr+v Eqrr+iyd +tmL FUN_001415-T1 137 RL--------------RSMSTFDQKMAKWKRTVTEQRRTIYDARTML 169 22..............2245689999********************8 PP >> SP_C-Propep Surfactant protein C, N terminal propeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 1.8 6.4e+03 20 45 .. 29 55 .. 17 63 .. 0.63 2 ! 16.2 0.3 2.5e-06 0.0093 25 88 .. 75 139 .. 57 147 .. 0.70 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.8 SP_C-Propep 20 saasrgrlripc.cplnlkrllivvvv 45 s a+ +r c cp + ++ iv v FUN_001415-T1 29 SEAQYDDVRCKCiCPKEGNKTAIVSNV 55 555555556555567666666665554 PP == domain 2 score: 16.2 bits; conditional E-value: 2.5e-06 SP_C-Propep 25 grlripc.cplnlkr..llivvvvvvlvvvvvlgallmglhmsqkhtemvlemsigapevqqrlals 88 ++ + c c + + l+ vv++ +lvv+ +l l+ l + k +e+si a e q+r+ l FUN_001415-T1 75 EQFCLRCmCKYEARNtsLIKVVIIFILVVIGILCLYLVFLFIDSKRRP--VELSITADEQQERFRLR 139 555565534444433115556666777888888888888888888765..799*********99875 PP >> Gemini_mov Geminivirus putative movement protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.1 1.4e-05 0.051 29 58 .. 87 116 .. 71 119 .. 0.88 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.4e-05 Gemini_mov 29 sselpwsrvveiaivilvaVlvlyLlytlv 58 + ++ +vv+i i++++ +l+lyL+++++ FUN_001415-T1 87 ARNTSLIKVVIIFILVVIGILCLYLVFLFI 116 6677888*******************9875 PP >> PH_2nd_LRR Second PH domain in LRR-containing protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 3e-05 0.11 20 91 .. 64 141 .. 58 148 .. 0.69 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 3e-05 PH_2nd_LRR 20 hfqvfkVvqresrkks.....grsssddltKlvstvvyLaiGihkvhliplpk.ssdrssslslkelesrdsfGlltL 91 ++++ +vqre++ ++ + l K+v ++ +iGi ++l+ l s++r +ls++ e++++f l ++ FUN_001415-T1 64 DCNCEYIVQREEQFCLrcmckYEARNTSLIKVVIIFILVVIGILCLYLVFLFIdSKRRPVELSITADEQQERFRLRSM 141 55555666666554322222246778899*********************9961555556667777777788766555 PP >> DUF2207_C Predicted membrane protein (DUF2207) C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 0.1 0.0016 6 163 184 .. 28 110 .. 3 122 .. 0.52 2 ? 4.1 1.0 0.012 45 101 129 .. 135 165 .. 111 169 .. 0.70 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0016 DUF2207_C 163 l................................................................aslllllllallvislivlll 184 + + ++++ +lv+++i++l+ FUN_001415-T1 28 FseaqyddvrckcicpkegnktaivsnvfiravdakdcnceyivqreeqfclrcmckyearntslI---KVVIIFILVVIGILCLY 110 333445566666666666666666666666666666666666666666666666666666664321...22222222222222222 PP == domain 2 score: 4.1 bits; conditional E-value: 0.012 DUF2207_C 101 k....kakkfskafkkwqeavkkeadergyfds 129 + ++f +++ kw++ v++ ++r +d+ FUN_001415-T1 135 RfrlrSMSTFDQKMAKWKRTVTE--QRRTIYDA 165 23345889***************..88888876 PP >> Sigma_reg_N Sigma factor regulator N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.19 6.9e+02 16 37 .. 13 34 .. 6 57 .. 0.61 2 ? 9.9 0.3 0.00032 1.2 7 40 .. 87 120 .. 84 134 .. 0.78 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.19 Sigma_reg_N 16 vlislivallivvillvtieyy 37 v +++++ l+++++++ ++y+ FUN_001415-T1 13 VSFIVAISSLVFLVTFSEAQYD 34 3334444444444445555554 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00032 Sigma_reg_N 7 aKrksrlrivlislivallivvillvtieyyask 40 a+++s++++v+i ++v++ i+ + lv ++++ FUN_001415-T1 87 ARNTSLIKVVIIFILVVIGILCLYLVFLFIDSKR 120 7899999999999999999988887766666554 PP >> DUF3930 Protein of unknown function (DUF3930) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 3.6 0.00035 1.3 23 48 .. 91 116 .. 86 118 .. 0.80 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00035 DUF3930 23 sLikilfiF.LiivGiPYtAYvvvqFi 48 sLik+++iF L+++Gi Y+v+ Fi FUN_001415-T1 91 SLIKVVIIFiLVVIGI-LCLYLVFLFI 116 8********4456687.6789999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (170 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1683 (0.0658837); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1703.99 // Query: FUN_001416-T1 [L=451] Description: FUN_001416 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-76 256.7 0.0 4.3e-76 256.3 0.0 1.2 1 Pkinase Protein kinase domain 7e-47 160.4 0.0 9.6e-47 159.9 0.0 1.1 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.5e-06 28.2 0.0 3.9e-05 23.6 0.0 2.2 2 Kinase-like Kinase-like 1.2e-05 25.3 0.3 2e-05 24.6 0.3 1.3 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.0013 18.9 0.2 0.0024 18.1 0.2 1.3 1 YrbL-PhoP_reg PhoP regulatory network protein YrbL 0.0016 17.7 0.1 0.0016 17.7 0.1 2.0 2 Pkinase_fungal Fungal protein kinase ------ inclusion threshold ------ 9.1 7.1 8.4 92 3.9 5.1 2.8 3 BRF1 Brf1-like TBP-binding domain Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 256.3 0.0 1.2e-79 4.3e-76 1 262 [] 30 292 .. 30 292 .. 0.94 Alignments for each domain: == domain 1 score: 256.3 bits; conditional E-value: 1.2e-79 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgals 96 ye +e lG+Gsfg+V++a++k +g+++AiK ++keka ++ k + rE+ i+kk++h+++v+l +++e+++++ylv+E+++ g +++ll++k+ +s FUN_001416-T1 30 YEFGEVLGRGSFGVVKEATNKISGRKWAIKAVNKEKAGTSAVKLLEREVLIMKKIDHQHLVHLEEIYETSKRMYLVMELCDAGGIEKLLEQKKRFS 125 78999**********************************999****************************************************** PP Pkinase 97 eeeakkilkqilegleylHsegvvHrDlKpeNiLidekge.....lKitDFGlakelesssk...ltsfvgtseYmAPEvlkskkygkkvDvWslG 184 e+e+ +++kq++++++ylH+ +vHrDlK eNiL+++ +K+tDFGl+ + ++s++gt+ YmAPEv+++ +y++++D+WslG FUN_001416-T1 126 EKETWTVIKQLAHAVAYLHDSDIVHRDLKLENILLSHPVAnelfnIKLTDFGLSYVRGGVGSdsmMQSVCGTPIYMAPEVITDLGYSQQCDIWSLG 221 ************************************533357899*********87655444556******************************* PP Pkinase 185 vilyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 vi+y+lltg+ppf ae+e++ +e + + e++++ p ++s+ ++ak+ll ++lk+dp +R ta+e+l+hpw+ FUN_001416-T1 222 VIMYTLLTGRPPFVAETEEKLYELIKKG-------EVDFSDPCWQSCPDSAKNLLLGMLKVDPAHRRTAKEILNHPWI 292 **************88888877777777.......99****************************************7 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.9 0.0 2.6e-50 9.6e-47 2 256 .. 31 288 .. 30 289 .. 0.89 Alignments for each domain: == domain 1 score: 159.9 bits; conditional E-value: 2.6e-50 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlkeekekkkikVavKtlkeeaseee.keefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk 95 e++e lG+G+fG V ++t k + k a+K +++e+ ++ + + +e+ +mkk++h+++v+l ++ ++++++v+e+++ G +++ L++ FUN_001416-T1 31 EFGEVLGRGSFGVVKEATNK----ISGRKWAIKAVNKEKAGTSaVKLLEREVLIMKKIDHQHLVHLEEIYETSKRMYLVMELCDAGGIEKLLEQ- 120 67899*************99....88999******665555551555666****************************************9999. PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse.....kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsks 185 k+++s ke+ +++q+A++++yL++ ++vHrdl N+L+s+ +k++DfGL+ + ++ ++ +mapE++++ +++++ FUN_001416-T1 121 KKRFSEKETWTVIKQLAHAVAYLHDSDIVHRDLKLENILLSHpvaneLFNIKLTDFGLSYVRGGVGSDSMMQSVCGTPIYMAPEVITDLGYSQQC 215 799**************************************988865559*********988555555555554555559*************** PP PK_Tyr_Ser-Thr 186 DvWsfGvllwEiftlgeepykglkneevlelleeger...leqpencpeelyelmkeCweedpeeRptfkelve 256 D+Ws Gv+++ ++t g+ p+ ++e+++el+++ge ++ ++cp++ ++l+ + dp++R t ke+++ FUN_001416-T1 216 DIWSLGVIMYTLLT-GRPPFVAETEEKLYELIKKGEVdfsDPCWQSCPDSAKNLLLGMLKVDPAHRRTAKEILN 288 **************.*****************999864446888**************************9976 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.02 74 17 85 .. 33 105 .. 21 136 .. 0.71 2 ! 23.6 0.0 1.1e-08 3.9e-05 150 288 .. 132 279 .. 109 280 .. 0.75 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.02 Kinase-like 17 gsllkkgdssvvflvtdqetgedlevhvflmkekpskkdleklkeavlaial.....lrgiknpkeAkaylrll 85 g++l g ++vv ++t++ g + +++ + kek+ ++++ l+++vl +++ l +++ +e ++++l+ FUN_001416-T1 33 GEVLGRGSFGVVKEATNKISGRKWAIKA-VNKEKAGTSAVKLLEREVLIMKKidhqhLVHLEEIYETSKRMYLV 105 7899999******************996.57899999**********998761111133455555555555555 PP == domain 2 score: 23.6 bits; conditional E-value: 1.1e-08 Kinase-like 150 lTlqlirlaasLqskglvhgkfsvdnlll.....dekggvflggfeaLvragtkvv.seve.....kgfaPpEllgsrgglytrknktlmtfklda 234 + ql +a+L++ +vh +++ +n+ll +e + ++l++f+ + g + s ++ + pE+ + + + d FUN_001416-T1 132 VIKQLAHAVAYLHDSDIVHRDLKLENILLshpvaNELFNIKLTDFGLSYVRGGVGSdSMMQsvcgtPIYMAPEVITD----------LGYSQQCDI 217 44588899*******************993333346799******97766665555344332223334555666655..........556779*** PP Kinase-like 235 WqlGlvIysiwclklPltlvaeeakeew.......ifklck.kipekvklLlkkllrysqed 288 W lG+ +y + P+ +ee e +c p+ k Ll ++l+ + + FUN_001416-T1 218 WSLGVIMYTLLTGRPPFVAETEEKLYELikkgevdFSDPCWqSCPDSAKNLLLGMLKVDPAH 279 *********************99999988888885445786599************988665 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.3 5.5e-09 2e-05 91 166 .. 101 176 .. 48 183 .. 0.86 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 5.5e-09 Kdo 91 rAlllteklegaqdLedllaqwaelaeelrrallkavgrlirklhragvqHgdlyakhillqtek.eeeakasliDl 166 r l++e l +a +e+ll q + ++e+ + +k+++ +++ lh+ ++ H+dl +ill +e + + l D+ FUN_001416-T1 101 RMYLVME-LCDAGGIEKLLEQKKRFSEKETWTVIKQLAHAVAYLHDSDIVHRDLKLENILLSHPVaNELFNIKLTDF 176 4556665.6678889999**9899*************************************9988678888888888 PP >> YrbL-PhoP_reg PhoP regulatory network protein YrbL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.2 6.6e-07 0.0024 49 151 .. 76 175 .. 50 180 .. 0.76 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 6.6e-07 YrbL-PhoP_reg 49 eyvklsklrkeidnsaiarilGlveTdlGlGlvvekitdfdGelaktleelvkkdeldk.elkrkLdefkeylldnhivindlsakNivlkrnseg 143 ++v k+id +++ + + eT++ + lv+e + +G + k le+ + e ++ ++ ++L + ++yl d +iv +dl+ +Ni+l + ++ FUN_001416-T1 76 REVLI---MKKIDHQHLVHLEEIYETSKRMYLVMELCD--AGGIEKLLEQKKRFSEKETwTVIKQLAHAVAYLHDSDIVHRDLKLENILLSHPVAN 166 34443...478899999999999999999999999875..58899999999887666666899**************************9887776 PP YrbL-PhoP_reg 144 e.ealvliD 151 e ++++l D FUN_001416-T1 167 ElFNIKLTD 175 645555555 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.1 4.5e-07 0.0016 286 376 .. 127 217 .. 48 228 .. 0.87 2 ? -0.3 1.0 0.13 4.8e+02 222 251 .. 314 363 .. 295 425 .. 0.50 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 4.5e-07 Pkinase_fungal 286 keLLealrdaikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielse.ssasgarertGTleFmaiellkgeeHtyrhDL 376 ke ++++ +a L+ + i+HrD +Ni++ + ++ + L D+ l+ + s+s + GT +ma e++ + + + D+ FUN_001416-T1 127 KETWTVIKQLAHAVAYLH-DSDIVHRDLKLENILLSHPVANELFNIKLTDFGLSYVRGGvGSDSMMQSVCGTPIYMAPEVITDLGYSQQCDI 217 555566666667777899.9******************9999***********99999878888889*************997766666665 PP == domain 2 score: -0.3 bits; conditional E-value: 0.13 Pkinase_fungal 222 eiRkgldftkaeslrskkkvas...................lssarkk.....s 251 e+R+g d +++++ +++ ++a kk + FUN_001416-T1 314 ELRQGSDNQDDQEANNNMDTAVedglvtsteascgtqkensE----KKqsnsaK 363 444444444443222222211134443333333333221110....11111111 PP >> BRF1 Brf1-like TBP-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.042 1.5e+02 67 98 .. 60 92 .. 24 94 .. 0.79 2 ? -2.3 0.0 2.2 8.1e+03 77 92 .. 114 130 .. 111 137 .. 0.66 3 ? 3.9 5.1 0.025 92 40 89 .. 322 388 .. 297 389 .. 0.63 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.042 BRF1 67 agpastaaEavkkmlkkkk.lskkINydaLksL 98 a +++ a+ ++ k+l+++ ++kkI+ + L +L FUN_001416-T1 60 AVNKEKAGTSAVKLLEREVlIMKKIDHQHLVHL 92 33789999**********77******9999777 PP == domain 2 score: -2.3 bits; conditional E-value: 2.2 BRF1 77 vkkmlkkkk.lskkINy 92 ++k+l++kk +s+k FUN_001416-T1 114 IEKLLEQKKrFSEKETW 130 67788877658887555 PP == domain 3 score: 3.9 bits; conditional E-value: 0.025 BRF1 40 elkeeaeeee................a.kkkkkkrkrkkkkkkkagpastaaEavkkmlkkkklskk 89 + +ea+++ + +k++ ++k++++ k++a+p+++a + +k ++++++s+k FUN_001416-T1 322 QDDQEANNNMdtavedglvtsteascGtQKENSEKKQSNSAKSSATPKKSAPSSNRKSVQSSQVSRK 388 333333333356667777777776552333333333444444557799************9999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (451 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1762 (0.0689763); expected 510.9 (0.02) Passed bias filter: 726 (0.0284204); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.39 # Mc/sec: 4625.29 // Query: FUN_001417-T1 [L=672] Description: FUN_001417 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-38 129.6 0.5 1.5e-37 128.9 0.5 1.3 1 NOT2_3_5_C NOT2/NOT3/NOT5 C-terminal Domain annotation for each model (and alignments): >> NOT2_3_5_C NOT2/NOT3/NOT5 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 128.9 0.5 6e-42 1.5e-37 1 126 [] 536 661 .. 536 661 .. 0.97 Alignments for each domain: == domain 1 score: 128.9 bits; conditional E-value: 6e-42 NOT2_3_5_C 1 sstfnspwsedaekpyepefklpeeypqepleklelspekfskleeetLFyiFYsspgdlqqllAakeLkkrsWrfhkklklWftreekeepkeit 96 ++tf sp+++++++p+e+++++p+ey+ ++ + +l+p k s+++e++LFy++Y++ gd+ ql+Aa+eL++r+Wr+hk+++lW+tr+++ ep+ +t FUN_001417-T1 536 YHTFGSPFADSPCRPHEIDYHVPSEYRINSFIRDKLAPIKPSRYSEDLLFYLYYTNGGDILQLAAAAELYARDWRYHKEERLWLTRAPGVEPQLKT 631 5799**********************9999899999************************************************************ PP NOT2_3_5_C 97 eeyergtYiyFD.ytWekrrkkefkleyeeL 126 ++yergtY++FD tW+k+ kef+ley++L FUN_001417-T1 632 SSYERGTYYFFDcSTWRKVA-KEFHLEYDKL 661 ************88******.*******987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (672 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 598 (0.0234097); expected 510.9 (0.02) Passed bias filter: 409 (0.016011); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 6445.19 // Query: FUN_001417-T2 [L=511] Description: FUN_001417 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-38 130.2 0.5 9.7e-38 129.6 0.5 1.3 1 NOT2_3_5_C NOT2/NOT3/NOT5 C-terminal Domain annotation for each model (and alignments): >> NOT2_3_5_C NOT2/NOT3/NOT5 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.6 0.5 3.8e-42 9.7e-38 1 126 [] 375 500 .. 375 500 .. 0.97 Alignments for each domain: == domain 1 score: 129.6 bits; conditional E-value: 3.8e-42 NOT2_3_5_C 1 sstfnspwsedaekpyepefklpeeypqepleklelspekfskleeetLFyiFYsspgdlqqllAakeLkkrsWrfhkklklWftreekeepkeit 96 ++tf sp+++++++p+e+++++p+ey+ ++ + +l+p k s+++e++LFy++Y++ gd+ ql+Aa+eL++r+Wr+hk+++lW+tr+++ ep+ +t FUN_001417-T2 375 YHTFGSPFADSPCRPHEIDYHVPSEYRINSFIRDKLAPIKPSRYSEDLLFYLYYTNGGDILQLAAAAELYARDWRYHKEERLWLTRAPGVEPQLKT 470 5799**********************9999899999************************************************************ PP NOT2_3_5_C 97 eeyergtYiyFD.ytWekrrkkefkleyeeL 126 ++yergtY++FD tW+k+ kef+ley++L FUN_001417-T2 471 SSYERGTYYFFDcSTWRKVA-KEFHLEYDKL 500 ************88******.*******987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (511 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 607 (0.023762); expected 510.9 (0.02) Passed bias filter: 426 (0.0166765); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.43s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 5042.30 // Query: FUN_001417-T3 [L=603] Description: FUN_001417 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (603 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 478 (0.0187121); expected 510.9 (0.02) Passed bias filter: 290 (0.0113525); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 6032.13 // Query: FUN_001417-T4 [L=533] Description: FUN_001417 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (533 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 574 (0.0224702); expected 510.9 (0.02) Passed bias filter: 352 (0.0137796); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 5189.65 // Query: FUN_001418-T1 [L=764] Description: FUN_001418 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-179 596.9 0.0 6.2e-179 596.7 0.0 1.0 1 Carn_acyltransf Choline/Carnitine o-acyltransferase 9.7e-15 54.7 0.2 2.3e-14 53.5 0.2 1.7 1 CPT_N Carnitine O-palmitoyltransferase N-terminus Domain annotation for each model (and alignments): >> Carn_acyltransf Choline/Carnitine o-acyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 596.7 0.0 4.9e-183 6.2e-179 1 574 [] 174 753 .. 174 753 .. 0.90 Alignments for each domain: == domain 1 score: 596.7 bits; conditional E-value: 4.9e-183 Carn_acyltransf 1 lPvPsLeeTleryleslkpllseeelekteklveeflkgeGekLqerLeerakkkeetnWledwWedyaYleyrdplvvnsnpflvlekedpkk 94 lPvP+L+ T +ryles++p+lsee ++k+ekl+eef++g+G++Lq++L+ ++ ++ n+++dwW++ +Yl++r+pl++nsn++ + + p+ FUN_001418-T1 174 LPVPDLDATTKRYLESVRPILSEERFKKMEKLAEEFKNGLGKRLQRYLVWKSWWST--NYISDWWQQFVYLRSREPLMINSNYYGFDPMQCPS- 264 8***********************************************99988866..***************************77665665. PP Carn_acyltransf 95 kdeetqlkraAklivaalefkkkldreelepevr..gkplcmsqykrlfnttRiPgkerDklktakeslkesrhivVlrkgqfykvdvldsdgk 186 + q +raA++i++++ ++k++++e+l+p+++ +plc++q+++ fnttRiP ke+D+l+++ +s +h+v++++g+f+ ++ ++ +g FUN_001418-T1 265 ---RIQSARAANVIHSLFLYRKQIRKEKLQPQFSmgIIPLCSEQFRKTFNTTRIPLKEQDHLHHHGSS----THVVIYHRGRFFYLQAFH-RGL 350 ...4899************************88555666*********************99999999....*****************8.599 PP Carn_acyltransf 187 llspeelekqlqeIledeskseeeeeeeepvGvLTtenRdeWakareellklspkNkesleaIesalfvvcLDdeepkaksllegs....hgkg 276 ll+p++lekq+ +Il+desk + + ee +++LTt +R+ Wa++r+++++ + Nk+sl++Ie+a+f++ L+d e +++++++ + FUN_001418-T1 351 LLKPADLEKQILHILQDESK---PVSGEELLPALTTAERNLWADTRSTYFS-TGVNKQSLDCIEQAAFFLNLEDLELDYREEECEDtdsfGRYL 440 ***************97555...456899********************77.556*******************99866666666668855666 PP Carn_acyltransf 277 sqgggtnRWfDKslqlivtknGkaglngEHspaDgtvvlrlvey......vlksikeekss...ksssssssseaepekLefeldeelkeaiee 361 ++g+g++ WfDKs++ ++knG++g+++EHs+aD++++++l ey l + + + + + + +p +L++++ e++ ie+ FUN_001418-T1 441 LHGNGHSCWFDKSFSAYIFKNGRFGMTAEHSWADAPIMSHLGEYialdefFLLGY-----KedgHCKGEPEFNLRPPSRLQWDIPEKCVGIIET 529 6666****************************************75555422222.....2333445555555555****************** PP Carn_acyltransf 362 aeerldklisdldlkvlefkeyGknfikkfklspDafvQmalQlAyyrlhgklaatyEsastrkFrhGRtEtirsvteesvafvkamldpsasd 455 ++e++++li+dldl++l ++ +Gk+ ikk+klspD+f+Qm lQlAy++++g++ tyEs++tr+Fr+GRtEt+r++t +s+afv+aml+ps+++ FUN_001418-T1 530 CQEKAEDLIKDLDLHILVHNAFGKGAIKKMKLSPDGFIQMGLQLAYFKDQGHFSLTYESSMTRLFREGRTETVRPCTVDSCAFVRAMLNPSSTK 623 ********************************************************************************************** PP Carn_acyltransf 456 eeklellrkAvkahskltkeaskGkGvdrHLfgLklvakeeelepplfsdpaykkssnwvLsTSqlssealel.............fgfgpvvp 536 +ek+el+ kAv++h++ k+a++G+GvdrHLfgL++v+k+ e++ p++ + + w+LsTSq+ +++l +gfgpv++ FUN_001418-T1 624 SEKKELMLKAVETHVTGFKKAMSGEGVDRHLFGLYVVSKYLEQDSPFLIEA---LKEPWKLSTSQTATQQLTKtnydkmpglrtagGGFGPVAD 714 ******************************************988866666...3468**********985446778888899999******** PP Carn_acyltransf 537 dGyGiaYiikdds.ikfvisskkssketsterfakaLee 574 dGyG++Yii +++ i f++++k ss++t+ +rf++ ++e FUN_001418-T1 715 DGYGVSYIISGEEvIYFHVTCKVSSQRTDCKRFSERIKE 753 *********777758888999999**********99875 PP >> CPT_N Carnitine O-palmitoyltransferase N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.5 0.2 1.8e-18 2.3e-14 1 44 [. 1 44 [. 1 47 [. 0.97 Alignments for each domain: == domain 1 score: 53.5 bits; conditional E-value: 1.8e-18 CPT_N 1 MAEAhqAVAFqftvtseGidvqlsqevlkeiylsgvrSwkkrli 44 MAEA+ VAFqf+vt+eGi v++++++lk + +++++S k+r++ FUN_001418-T1 1 MAEARLGVAFQFQVTEEGIIVNYDRNALKFVGRAVMKSAKRRVK 44 ******************************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (764 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 797 (0.0311998); expected 510.9 (0.02) Passed bias filter: 709 (0.0277549); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.38s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7289.81 // Query: FUN_001419-T1 [L=1271] Description: FUN_001419 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-13 49.1 18.7 5.9e-13 49.1 18.7 1.8 2 Ion_trans Ion transport protein 4.3e-05 24.1 0.1 9.8e-05 22.9 0.1 1.5 1 SPRY SPRY domain 0.0018 19.0 0.3 0.019 15.7 0.3 2.3 1 VWA von Willebrand factor type A domain ------ inclusion threshold ------ 0.022 15.4 0.5 0.049 14.2 0.5 1.6 1 DpnI_C Dam-replacing HTH domain 3.7 7.3 9.0 0.085 12.7 0.8 2.3 3 SF-assemblin SF-assemblin/beta giardin Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.7 0.41 2.1e+03 62 85 .. 236 258 .. 227 280 .. 0.71 2 ! 49.1 18.7 1.1e-16 5.9e-13 20 241 .. 512 766 .. 503 768 .. 0.78 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.41 Ion_trans 62 kYlrspwnilDfvvvlpslislil 85 + + + w+++D ++ ++++ + + FUN_001419-T1 236 WIFLNIWCLFDSLMFPLLFALF-W 258 5678889999999988777744.3 PP == domain 2 score: 49.1 bits; conditional E-value: 1.1e-16 Ion_trans 20 aletyfqpeekelklleildlvftviftlemllkiialgl.................kkkYlrspwnilDfvvvlpslislil.........ses. 88 al+++ + + ++ +l l+++++++f+ ml++i ++kYl++ wn+lDf+ ++++l++++l s + FUN_001419-T1 512 ALHFAICLSPST-VPLSGLEWAILMFFLGRMLVEIQQITTikkrkngnvngrtqrstTRKYLSDAWNVLDFITLVIYLLTFFLrtitwglstS-Ti 605 445555554555.789999999999999999999988666788999*************************************9998887651.14 PP Ion_trans 89 ...k..eslsllrvlrll.rllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkke.ekewenpdngrtn...Fd 174 +++ ++ +l l + ++++ +eg+ ++ +l+++++++ n+++ ++ +++f+i+ ++ + e++ +++ n+ t ++ FUN_001419-T1 606 nnrAivVAGYFYGINTMLlTLRSFGQVMETSEGVGVIQIALFQMFGDITNIFWQFIAAVLAFSIAITKVY------MaERSYISKRNNITQglvCE 695 444144455555555555334445567777777777666***************************9999......445566666666666777** PP Ion_trans 175 nfgnallwlfq.....tlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqelter 241 + g++ +w++ +l + d+l+ + i +++++f++lg +ll+n++ia++++++q+++++ FUN_001419-T1 696 TPGMSCWWTMMkhlfwSLLGLAELDTLDSIDHTS-VTIVHFLYGVFLVLGVILLVNMMIALLNNTYQKVQDN 766 *999999987765444666665566555555555.999999***************************9976 PP >> SPRY SPRY domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.1 1.9e-08 9.8e-05 4 108 .. 941 1062 .. 939 1072 .. 0.76 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.9e-08 SPRY 4 fevevegqekgsvrvGvatksvprkgekflgdeegswgydgwkgkky......sastsestglplfeegdviGcflDleeg......eisFtkn 85 fev ++ +++ sv vG + + + +++ ++g ++g +gy ++gk++ +a+++ ++++ + gdviGc + + ++ ei Ft n FUN_001419-T1 941 FEVLIQ-ESGRSVGVGAVWQYY--GNHAMPGCKDGTVGYIVNQGKVFgpclpvNAERGLEYENAVAYRGDVIGCSVEFGDEenpdevEIVFTLN 1031 888888.555555566555555..5****************************************************98887788889****** PP SPRY 86 gksl.........gvaFrkvsfagklfPavsl 108 gk+ + +r f+ +++P+v++ FUN_001419-T1 1032 GKPItsdkirmpyTLDYR-GGFSMEIYPYVCM 1062 *87655555542222222.1223566666665 PP >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.3 3.7e-06 0.019 2 165 .. 277 466 .. 276 475 .. 0.75 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 3.7e-06 VWA 2 ivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqys.....................sevrtefslndysskeellsavkslkykgg 76 ++fl+ + + + +e+f +k+++++++e+ +d+t++ ++ +++ t + ++ + ke ++vk+l+ + FUN_001419-T1 277 VAFLINATSDLAQETFPLMKDTVQRFIEEHG--DDQTKYQIIIHDkkskkqyydetrsnlrcfddpDSYPTDTRPRESKPKEVDAENVKNLENGNA 370 899*************************999..56666666655555555555555555555545555888888888888899999*****99999 PP VWA 77 gttntgkalkyalenlfkssagaRegapkvvvlltdGksqdg.dveeaarelk......sagvkvfavgvgn.adeeeLekiasepd.eghvftve 163 + + l++a +++f ++++ + + kv++ ltd k++ +++++ r+++ + +k+ vgvg d +eLe +++e++ + +v+ v FUN_001419-T1 371 KFPALHRDLDMANKYFFAKTRE--SPVDKVIIYLTDHKTSLRrKIKKVKRRARdlkkkrKTEIKLLPVGVGPyIDIRELEGVTKENTqDLNVIHVG 464 9999******************..667*********88854344444444444555776779********66145555999888888555556655 PP VWA 164 df 165 ++ FUN_001419-T1 465 EY 466 55 PP >> DpnI_C Dam-replacing HTH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.5 9.7e-06 0.049 8 57 .. 1209 1260 .. 1202 1264 .. 0.85 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 9.7e-06 DpnI_C 8 dvlacidklekeeFt..lqdlykfeeklklkhpkNnfikdKirqqLqilRDk 57 d l+ +d ke+F l+ l e++++ + +N+ +++Ki+ +Lq lRD FUN_001419-T1 1209 DDLKKVDSTAKEKFDllLKGLGDLEDNFQSETEENKKMRSKIQEKLQELRDL 1260 567788888889887335899999***************************6 PP >> SF-assemblin SF-assemblin/beta giardin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.2 1.5 7.8e+03 6 8 .. 412 414 .. 389 433 .. 0.46 2 ? -1.3 0.1 0.31 1.6e+03 126 161 .. 1089 1124 .. 1076 1141 .. 0.54 3 ? 12.7 0.8 1.7e-05 0.085 108 162 .. 1207 1261 .. 1198 1268 .. 0.81 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 1.5 SF-assemblin 6 Kle 8 K++ FUN_001419-T1 412 KIK 414 222 PP == domain 2 score: -1.3 bits; conditional E-value: 0.31 SF-assemblin 126 lvkelneleaaideEkaerkkkedqlnkkveEdlkk 161 +k + ++ ++i+e + + k d+++++ + l FUN_001419-T1 1089 DIKAITQVTSNIAETVNSKFKAADEVVQRCQRALSN 1124 445555555555555555555555555544443333 PP == domain 3 score: 12.7 bits; conditional E-value: 1.7e-05 SF-assemblin 108 venekakrrdaieklakelvkelneleaaideEkaerkkkedqlnkkveEdlkkl 162 + ++ +k + +++ + l+k l +le +++ E e+kk++ ++ +k++E ++ FUN_001419-T1 1207 ICDDLKKVDSTAKEKFDLLLKGLGDLEDNFQSETEENKKMRSKIQEKLQELRDLI 1261 55555566666666777789*****************************976555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1271 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2009 (0.0786455); expected 510.9 (0.02) Passed bias filter: 1141 (0.0446663); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.58u 0.39s 00:00:00.97 Elapsed: 00:00:00.44 # Mc/sec: 11614.63 // Query: FUN_001421-T1 [L=2525] Description: FUN_001421 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-58 196.9 2.8 6.8e-58 196.9 2.8 3.0 2 AAA_11 AAA domain 1.2e-55 188.6 1.5 3.3e-55 187.2 0.0 2.3 2 AAA_12 AAA domain 2.3e-22 79.6 2.7 4.3e-22 78.7 2.7 1.4 1 SEN1_N SEN1 N terminal 2.7e-09 37.7 0.2 0.0047 17.3 0.0 3.8 3 Viral_helicase1 Viral superfamily 1 RNA helicase core do 1.9e-08 35.1 0.0 6.2e-07 30.1 0.0 2.7 1 AAA_19 AAA domain 2e-07 31.4 0.1 6.7e-07 29.7 0.1 1.8 1 UvrD-helicase UvrD/REP helicase N-terminal domain 3e-06 27.6 0.0 0.014 15.6 0.0 2.5 2 AAA_30 AAA domain 9.3e-05 22.3 0.3 0.0039 17.0 0.0 3.1 3 SLFN-g3_helicase Schlafen group 3, DNA/RNA helicase domai ------ inclusion threshold ------ 0.018 15.4 4.6 0.064 13.7 4.6 1.9 1 EXOC6_Sec15_N Exocyst complex component EXOC6/Sec15, N 0.052 13.9 0.0 0.12 12.7 0.0 1.7 1 UvrD_C_2 UvrD-like helicase C-terminal domain 0.074 14.1 0.0 0.23 12.4 0.0 1.8 1 AAA_16 AAA ATPase domain 0.12 12.8 0.1 2.3 8.6 0.0 2.6 2 ResIII Type III restriction enzyme, res subunit 0.12 13.2 0.0 5.9 7.7 0.0 3.0 2 AAA_22 AAA domain 0.22 11.9 0.0 0.61 10.4 0.0 1.8 1 NAT10_TcmA_helicase RNA cytidine acetyltransferase NAT10/Tcm 0.31 12.0 1.4 4.3 8.3 0.0 3.1 3 BMFP Membrane fusogenic activity 0.89 9.6 5.0 2 8.4 5.0 1.5 1 FapA Flagellar Assembly Protein A beta soleno Domain annotation for each model (and alignments): >> AAA_11 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 196.9 2.8 4.3e-61 6.8e-58 2 257 .] 1336 1654 .. 1335 1654 .. 0.76 2 ? -3.5 2.5 6.2 9.8e+03 90 174 .. 2045 2095 .. 1955 2138 .. 0.53 Alignments for each domain: == domain 1 score: 196.9 bits; conditional E-value: 4.3e-61 AAA_11 2 lndsqreaiksalseee.......fsliqGPPGtGKTktivelisqllsk........k..aekkaakkriLvCapsNaAvDnllerllr.... 74 +n+sq++ i+ ++ + ++l+qGPPGtGK+ tiv+li+ +l++ + ++ a+k riL+CapsNaA+D+l+ + r FUN_001421-T1 1336 YNASQEKVISCGTNAMHlpypiprVCLVQGPPGTGKSYTIVGLIKEILNRrqepaaqpTtgSPVLANKYRILLCAPSNAAIDELIGQIKRarir 1429 688888888766666667777788***********************95555566655257899************************999988 PP AAA_11 75 ............ldskgekkkv................kvvRighpereriseavkevsleelvekklekee..................kaql 122 + +vR+g+++ +++++v+e+ le++ ++kl++++ FUN_001421-T1 1430 ldmkqdnkenwrR--------NqqsafqkaslkncgdvTLVRVGRKS--QVHSSVSEFWLETMAKNKLQEKRsvstvdvninehkddlnaC--- 1510 6665555444440........05555666666666666*********..89*****************99875555555555543333331... PP AAA_11 123 akeiskeleklekklrakeeeekk.......................ekllksaekekskleqerkklkseskelrkelekreekleeeildea 193 ++e ++ + l++++++ k++++ + kl++e k+ ++ l ++e+++++eild+a FUN_001421-T1 1511 ------------------TAELEElekriwalqsttlsanqeieekiKDLKQKKDYLKNHRRVVQLKLRKE-KDKQNHLHREEARIRREILDSA 1585 ..................22222222235555555555666665543344444444444444444455444.5778889999999********* PP AAA_11 194 eivlsTlsgagskklssla.....kfdvviiDEAaqalEpstliPllkgvkkvvLvGDpkQLpptvisk 257 +iv++Tlsgags +l++ f +vi+DEA+qa+E+ +liPl ++++k+vLvGDp QLppt+is+ FUN_001421-T1 1586 DIVCTTLSGAGSTSLKQDYgrckcPFGCVIVDEACQATELDVLIPLEFKSSKLVLVGDPEQLPPTIISE 1654 ***************987778889*******************************************96 PP == domain 2 score: -3.5 bits; conditional E-value: 6.2 AAA_11 90 ghpereriseavkevsleelvekklekeekaqlakeiskeleklekklrakeeeekkekllksaekekskleqerkklkseskel 174 +++ ++++ e+s + ++++l+ + l+ ++++ s++eq+r++ + +l FUN_001421-T1 2045 QNDD----HRRMDELSSKGPISRELRT------------------------------DPALERRNNNPSNREQSRQEGAKHTCTL 2095 2222....2222222222222222222..............................2222222222222222222222222111 PP >> AAA_12 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.3 0.71 1.1e+03 24 65 .. 1468 1509 .. 1444 1559 .. 0.64 2 ! 187.2 0.0 2e-58 3.3e-55 3 194 .. 1663 1848 .. 1661 1849 .. 0.93 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.71 AAA_12 24 YRmhpeIsefpsklfYegkLkdgesvaerelevlekleeplk 65 h+++sef +++ ++kL++++sv++ +++e++++ ++ FUN_001421-T1 1468 SQVHSSVSEFWLETMAKNKLQEKRSVSTVDVNINEHKDDLNA 1509 457999******************999998885555544443 PP == domain 2 score: 187.2 bits; conditional E-value: 2e-58 AAA_12 3 rslferlleag.....eekvvlLdtqYRmhpeIsefpsklfYegkLkdgesvaerelevlekleeplkplvfldvkkseeeeekeeksyiNeeE 91 s+f+rl++ ++v++L++qYRmhpeI++fps++fY+++Lk+++s+++r+ + ++++ ++dv + +e + ++ ++N++E FUN_001421-T1 1663 LSMFQRLYKFFrhndlGRPVMMLEEQYRMHPEIASFPSRHFYSSRLKCHRSLETRPFS-------LKEHYRVFDVIRGQEVHLER-GALCNPTE 1748 5999999987777788899*************************************99.......788899****9999999987.9******* PP AAA_12 92 aelvvelvekllksgveekkigvitpYkaQvellkealkekeeeeeeievntvDgfQGrEkdviilslVrsn.ekkeiGflkderrlNValTRA 184 ++lvvel++ l+k+ + +ig+itpYk+Q+ ++++l++++++ ievntvDgfQGrEkdv+ils+Vr++ ++++iGf+ d++r+NValTRA FUN_001421-T1 1749 VRLVVELCTLLTKMLYS-GSIGIITPYKKQKMDIQQKLSKDFSN---IEVNTVDGFQGREKDVVILSCVRAKnNRASIGFVGDRQRMNVALTRA 1838 *********99999988.58*******************87776...***********************954899****************** PP AAA_12 185 ksklivvGna 194 +++l+++G++ FUN_001421-T1 1839 RHALFILGDM 1848 ********96 PP >> SEN1_N SEN1 N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.7 2.7 2.7e-25 4.3e-22 9 348 .. 53 405 .. 46 430 .. 0.79 Alignments for each domain: == domain 1 score: 78.7 bits; conditional E-value: 2.7e-25 SEN1_N 9 LssCdkCvrnfhrgkkklrqtlaerfpeekvaqfldkldewdierilkgLekakeileekrkifsksslseslkevllalyeaLccpallrsdpel 104 L C +Cv+++hr ++ +q+ +++++ + ++dier+++ + a l +ss+++ l++++++l+e L p ll ++++l FUN_001421-T1 53 LCYCYDCVQEYHRLADEAKQNNPH-------SALFQEFLTLDIERLTHTIAGA---L--------ESSAEDVLTKLQVPLMEVLGFPYLL-HHKQL 129 778**********99998886433.......678899999***********93...2........3667788**************9999.77777 PP SEN1_N 105 ralfdkvfkllqtkkkplklsellPGmiyflfdgdeeerrWAekqleklkrsltkeefewavkdlleeaivhllklqadpae.............. 186 + f + + +++ + plkl e lPG +l++ +e+ r WA+++ ++l + +++++ +v+ + e + +++ + +++ FUN_001421-T1 130 ADQFVDGIIAVLKFSYPLKLEEKLPGAYLLLIHPNEKVRAWATRNARSLG-LISRDDYDILVE--VIEWMLGVVTFD--ISSnlialddiaihkfl 220 77777766677777999*******************9999******9965.344445555552..333343444433..11122334446668889 PP SEN1_N 187 .........ierfWsgfslilrlldkelithrlrakevkpklesiyrlllnhlsstl..eeplpdllralslLLeklgkafWd.algpispqvvld 270 +++W+g+ +++ ++d + + l + + ++ +++++l+++ e p+ ++l++++++ eklg+++W+ +++p+ v+d FUN_001421-T1 221 pphlfvtpsFSEYWTGLVVLVMQMDFATVRSCLMSSDE-NGHRDFLVTIMSNLQDQMeeEGPFWSVLQCFTVFTEKLGERIWQmPSFHYQPSGVFD 315 9999*****************************99443.3467999999999999987789**********************4455788****** PP SEN1_N 271 qifdnpaFkklLeesleeeeeveedssl..........sdllsWiepflkSlsssqrsdacrkllhfllerlqk..drysdsarparaac 348 i +n +++++++ l e+e ++++++ +++l W +pf++S ++ ++c + +++l++ +++s+ ++++++ + FUN_001421-T1 316 IITSNAVYTNYIQKRLGESEVTSHSQTAtngdskrrlyKTALVWFRPFVESFLDFESGELCVCEVLNYFHNLAEccSPQSTFKNEVQSLL 405 ***************9997777666544799********************977777777765555556666665544444454554444 PP >> Viral_helicase1 Viral superfamily 1 RNA helicase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.0 0.0051 8.1 2 36 .. 1362 1397 .. 1361 1414 .. 0.77 2 ! 9.3 0.0 0.00082 1.3 58 99 .. 1609 1649 .. 1567 1671 .. 0.85 3 ! 17.3 0.0 2.9e-06 0.0047 165 227 .. 1775 1845 .. 1686 1846 .. 0.65 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0051 Viral_helicase1 2 vvhGvpGcGKStlirkllktil.vikptaelrtegk 36 +v+G pG GKS i+ l+k+il ++ a+ t g+ FUN_001421-T1 1362 LVQGPPGTGKSYTIVGLIKEILnRRQEPAAQPTTGS 1397 79*****************97665555455555555 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00082 Viral_helicase1 58 tkgkililDEytklpaGyill.laakssaklvilfGDplQipy 99 + + +i+DE+++++ ++++ + + +++ ++l+GDp+Q p FUN_001421-T1 1609 CPFGCVIVDEACQAT--ELDVlIPLEFKSSKLVLVGDPEQLPP 1649 447789******999..8999777788999**********885 PP == domain 3 score: 17.3 bits; conditional E-value: 2.9e-06 Viral_helicase1 165 ltetqalleslgve.....vttvaevqGltfdsVtlvldketdlelis....esrellyvAlTRhrkslhil 227 +++++ + l+ + v+tv + qG + d+V+l + + +++ +s +r+ + vAlTR+r +l il FUN_001421-T1 1775 KKQKMDIQQKLSKDfsnieVNTVDGFQGREKDVVILSCVRAKNNR-ASigfvGDRQRMNVALTRARHALFIL 1845 3333333333333366667***************99766544333.44568888**************9997 PP >> AAA_19 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.1 0.0 3.9e-10 6.2e-07 12 131 .. 1359 1649 .. 1355 1651 .. 0.84 Alignments for each domain: == domain 1 score: 30.1 bits; conditional E-value: 3.9e-10 AAA_19 12 kvvlltgGpGtGKTtvikaivellkelkee...............aeillvaptgrAakrlaeatgle.....akTihrl.............. 71 +v+l+ g pGtGK+++i+++++ + ++++e +ill+ap + A ++l +++++ FUN_001421-T1 1359 RVCLVQGPPGTGKSYTIVGLIKEILNRRQEpaaqpttgspvlankYRILLCAPSNAAIDELIGQIKRArirldM-----Kqdnkenwrrnqqsa 1447 799*********************9999999******************************9999555344440.....145555566666666 PP AAA_19 72 .............................................................................................. 71 FUN_001421-T1 1448 fqkaslkncgdvtlvrvgrksqvhssvsefwletmaknklqekrsvstvdvninehkddlnactaeleelekriwalqsttlsanqeieekikd 1541 66778888888888888999999999******************************************************************** PP AAA_19 72 ..................................................lefddlevef.......ead.eekkleadllivDEvsmvdvlla 107 l ++d + k ++ivDE+ + + + FUN_001421-T1 1542 lkqkkdylknhrrvvqlklrkekdkqnhlhreearirreildsadivcttL--------SgagstslKQDyGRCKCPFGCVIVDEACQAT--EL 1625 ********************9999999999999999999977777665431........02233333333034444556*******9988..34 PP AAA_19 108 ykLlkalp.ekaklllVGDadQlps 131 L+ l ++ kl+lVGD++Qlp+ FUN_001421-T1 1626 DVLI-PLEfKSSKLVLVGDPEQLPP 1649 4455.45548899**********98 PP >> UvrD-helicase UvrD/REP helicase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.1 4.2e-10 6.7e-07 15 250 .. 1360 1646 .. 1350 1647 .. 0.66 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 4.2e-10 UvrD-helicase 15 pllvlAgAGsGKTrvlteriaylikekgiepee.............ilavTFTnkAakemkeriek.............llkkae......... 73 +lv + +G+GK+ +++ i +++++++ + + il+ +n+A +e+ +i++ FUN_001421-T1 1360 VCLVQGPPGTGKSYTIVGLIKEILNRRQEPAAQpttgspvlankyrILLCAPSNAAIDELIGQIKRarirldmkqdnkeN----Wrrnqqsafq 1449 68999*********************9866666888****************************9999977665555550....0555545555 PP UvrD-helicase 74 ............lselnisTfHsfclriLrkeakrlg......elkknfsildeed....qlkllkellekkkkkldekklekkeelkeliskl 145 ++ s +Hs +++ +++ + + +++i +++d ++ l+el k l++ l++++e++e i++l FUN_001421-T1 1450 kaslkncgdvtlVRVGRKSQVHSSVSEFWLETMAKNKlqekrsVSTVDVNINEHKDdlnaCTAELEELE-KRIWALQSTTLSANQEIEEKIKDL 1542 555667777777555555555554444433333333322333312233334444333333333333333.444566666666668888888888 PP UvrD-helicase 146 kneklspeelekalekaeeeekkaaevlkeyqeqlkennalDfddLllklle.....llkeneellealrerfkvilvDEyQDtnkiqyellkl 234 k++k ++ + + + ++ek+ ++ l+ +e+ ++++lD +d+++++l+ ++ +++ f ++vDE+ + + ++l FUN_001421-T1 1543 KQKKDYLKNHRRVVQLKLRKEKDKQNHLH-REEARIRREILDSADIVCTTLSgagstS---LKQDYGRCKCPFGCVIVDEACQATEL--DVLIP 1630 88777777766655444444444444444.4556667788***********9443322...23335678889********9665554..55556 PP UvrD-helicase 235 LakkkenlfvvGDpdQ 250 L k+++l++vGDp+Q FUN_001421-T1 1631 LEFKSSKLVLVGDPEQ 1646 6666678********9 PP >> AAA_30 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 8.8e-06 0.014 19 63 .. 1359 1420 .. 1353 1446 .. 0.89 2 ! 9.1 0.0 0.0009 1.4 67 130 .. 1586 1649 .. 1570 1656 .. 0.69 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 8.8e-06 AAA_30 19 rvqvlvGpAGtGKTtal.kalreaweaag................gevvglAptakaakvLa 63 rv++++Gp+GtGK++++ ++e+++++ ++++++Ap+++a ++L FUN_001421-T1 1359 RVCLVQGPPGTGKSYTIvGLIKEILNRRQepaaqpttgspvlankYRILLCAPSNAAIDELI 1420 699***********7761566999999877***************************99885 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0009 AAA_30 67 gieaeTiakllhela..grakleak.qllvvDEagmvdtrqlarllelaeaagakvllvGDtkQlqs 130 +i ++T+ + + + +++ ++vDEa ++ + ++ le + k++lvGD++Ql++ FUN_001421-T1 1586 DIVCTTLSGAGSTSLkqDYGRCKCPfGCVIVDEACQATELDVLIPLEFK---SSKLVLVGDPEQLPP 1649 55555555554332245333455555789******99988776666554...56**********985 PP >> SLFN-g3_helicase Schlafen group 3, DNA/RNA helicase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 2.5e-06 0.0039 2 64 .. 1359 1421 .. 1358 1440 .. 0.84 2 ? 0.8 0.1 0.21 3.4e+02 35 93 .. 1546 1624 .. 1525 1640 .. 0.63 3 ? -1.1 0.0 0.79 1.3e+03 335 349 .. 1830 1844 .. 1811 1873 .. 0.80 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 2.5e-06 SLFN-g3_helicase 2 avvlveGgaGtGKsvvalnllaeleksdlkktanylsvNhplvlvlrealagdekkkikeafe 64 +v+lv+G +GtGKs+ + l+ e+ + +++ a+ +++ l +++r l+ +++ i+e + FUN_001421-T1 1359 RVCLVQGPPGTGKSYTIVGLIKEILNRRQEPAAQPTTGSPVLANKYRILLCAPSNAAIDELIG 1421 79**********************999999999999999999999999888877666666555 PP == domain 2 score: 0.8 bits; conditional E-value: 0.21 SLFN-g3_helicase 35 nylsvNhplvlvlrealagdekkkikeafekltsfinqls....................kekpkedvvivDEAhrlle 93 + ++Nh+ v l+ + ++d++++++++ +++ + i + + k ++ +vivDEA ++e FUN_001421-T1 1546 KDYLKNHRRVVQLKLRKEKDKQNHLHREEARIRREILDSAdivcttlsgagstslkqdygRCKCPFGCVIVDEACQATE 1624 44456666665555555555533333333333333322223666666677778777777789999*********88776 PP == domain 3 score: -1.1 bits; conditional E-value: 0.79 SLFN-g3_helicase 335 syrVlLtRGrkGlyv 349 +++V LtR+r+ l++ FUN_001421-T1 1830 RMNVALTRARHALFI 1844 567777777777776 PP >> EXOC6_Sec15_N Exocyst complex component EXOC6/Sec15, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 4.6 4e-05 0.064 13 73 .. 1496 1556 .. 1486 1565 .. 0.91 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 4e-05 EXOC6_Sec15_N 13 ieelcnenyqefissvdellsvrkeaeeLkseiaelneslqksgeellekkkelleakkvs 73 ++ +ne++++++ + el++ +k++ L+s ++ n+++++ ++l +kk+ l + ++v FUN_001421-T1 1496 VDVNINEHKDDLNACTAELEELEKRIWALQSTTLSANQEIEEKIKDLKQKKDYLKNHRRVV 1556 666799************************************************9999985 PP >> UvrD_C_2 UvrD-like helicase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 7.6e-05 0.12 4 51 .. 1794 1844 .. 1791 1845 .. 0.88 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 7.6e-05 UvrD_C_2 4 altvhkaqGsefpaVfvvdpdltahdedml...rrrlLYtavTRAkkklvl 51 + tv +qG e ++V++ ++ + + + + r+ +a+TRA++ l++ FUN_001421-T1 1794 VNTVDGFQGREKDVVILSCVRAKNNRASIGfvgDRQRMNVALTRARHALFI 1844 6699*************99999998866557779***************98 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00014 0.23 24 62 .. 1358 1401 .. 1350 1486 .. 0.61 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00014 AAA_16 24 pplvlvsGeaGvGKSalv.rellralera....alvlsgkcdel 62 p+++lv G++G+GKS + + + l+r+ a+ ++g + FUN_001421-T1 1358 PRVCLVQGPPGTGKSYTIvGLIKEILNRRqepaAQPTTGSPVLA 1401 699************98844444455555554322233333333 PP >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.0 0.0015 2.3 26 77 .. 1361 1427 .. 1334 1489 .. 0.76 2 ? 0.9 0.1 0.33 5.3e+02 87 134 .. 1559 1619 .. 1522 1633 .. 0.71 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0015 ResIII 26 glivmaTGsGKTlvaakliarlskkgkek...............kvlflvdrkeLleqakeefkkfl 77 l++ + G+GK+++++ li+++ + ++e ++l+ +++++ ++ + ++k+ FUN_001421-T1 1361 CLVQGPPGTGKSYTIVGLIKEILNRRQEPaaqpttgspvlankyRILLCAPSNAAIDELIGQIKRAR 1427 57999******************98777677788877777777777777777766666665555444 PP == domain 2 score: 0.9 bits; conditional E-value: 0.33 ResIII 87 ilsgdkkke.............ekkekkivvttiqslskalekekeellkdkfdviiiDEa 134 +l+++k+k+ ++++iv tt + + + + k++ k f+++i+DEa FUN_001421-T1 1559 KLRKEKDKQnhlhreearirreILDSADIVCTTLSGAGSTSLKQDYGRCKCPFGCVIVDEA 1619 3333333334455666666677779999**********9998888999999999******8 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.0037 5.9 6 55 .. 1359 1424 .. 1358 1454 .. 0.68 2 ? 1.7 0.0 0.27 4.3e+02 72 105 .. 1828 1863 .. 1791 1875 .. 0.83 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0037 AAA_22 6 gilvltGesGtGKTtllrrlleqldee................ddsvvlvelpsstspkdllrell 55 +++++ G++GtGK++++ l+++ ++ ++ +l +ps ++l+ ++ FUN_001421-T1 1359 RVCLVQGPPGTGKSYTIVGLIKEILNRrqepaaqpttgspvlaNKYRILLCAPSNAAIDELIGQIK 1424 578999**********99998888777677777777755554433333444444445666655555 PP == domain 2 score: 1.7 bits; conditional E-value: 0.27 AAA_22 72 laalqealkalaaravliiDEaqnl...seelleeLr 105 +++++ al +++ a++i+ ++q l s++++e L FUN_001421-T1 1828 RQRMNVALTRARH-ALFILGDMQTLksgSNDWMELLE 1863 5788888888888.***********654466666653 PP >> NAT10_TcmA_helicase RNA cytidine acetyltransferase NAT10/TcmA, helicase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00038 0.61 2 73 .. 1363 1450 .. 1362 1469 .. 0.83 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00038 NAT10_TcmA_helicase 2 itAdRGRGKSaalGlalaaliaegk................srilvtapskenvqtlfefakkglealglkeeekkekgekaelevek 73 ++++ G+GKS ++ ++++++++++ ril++aps++++++l+ ++k++ +l++k+ +k++ +++++ + +k FUN_001421-T1 1363 VQGPPGTGKSYTIVGLIKEILNRRQepaaqpttgspvlankYRILLCAPSNAAIDELIGQIKRARIRLDMKQDNKENWRRNQQSAFQK 1450 67889*****99888888888887779999********9999*******************999999999986665555555544444 PP >> BMFP Membrane fusogenic activity # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.0 0.0027 4.3 30 58 .. 165 193 .. 150 196 .. 0.93 2 ? -1.7 0.2 3.6 5.7e+03 4 43 .. 1413 1451 .. 1411 1453 .. 0.79 3 ? 0.2 0.1 0.89 1.4e+03 62 76 .. 1511 1525 .. 1505 1544 .. 0.77 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0027 BMFP 30 knvravlesalsklDlVtREEFDvqkevl 58 ++vra + + ++l l++R+++D++ ev+ FUN_001421-T1 165 EKVRAWATRNARSLGLISRDDYDILVEVI 193 789*********************99997 PP == domain 2 score: -1.7 bits; conditional E-value: 3.6 BMFP 4 nkllDdlakklsdalpaaaglreeveknvravlesalskl 43 n +D+l ++++a ++++ ++n r +sa++k FUN_001421-T1 1413 NAAIDELIGQIKRARI-RLDMKQDNKENWRRNQQSAFQKA 1451 7789999999988754.45569999999999999999986 PP == domain 3 score: 0.2 bits; conditional E-value: 0.89 BMFP 62 rekleaLearvaeLE 76 ++le+Le+r+ +L FUN_001421-T1 1511 TAELEELEKRIWALQ 1525 567888888887774 PP >> FapA Flagellar Assembly Protein A beta solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 5.0 0.0013 2 153 238 .. 1495 1578 .. 1472 1609 .. 0.75 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0013 FapA 153 elkekleeleeelkeleeeleklkkklkklpkkaekqldeekkeqleklletkekleeeleeleeelkelkeeleskkeeakikvn 238 +++ +++e +++l+ + +ele+l+k++ +l+++ + ++e +e+++ l+++k++l++ + ++ +l + k++ ++ ++e + +++ FUN_001421-T1 1495 TVDVNINEHKDDLNACTAELEELEKRIWALQSTTLS-ANQEIEEKIKDLKQKKDYLKNHRRVVQLKLRKEKDKQNHLHRE-EARIR 1578 566778888888888888888888888888884333.4688999999999999999999998888888877777777433.44444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2525 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1678 (0.065688); expected 510.9 (0.02) Passed bias filter: 736 (0.0288119); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.74u 0.41s 00:00:01.14 Elapsed: 00:00:00.44 # Mc/sec: 23183.18 // Query: FUN_001422-T1 [L=2289] Description: FUN_001422 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-45 152.4 18.6 9e-45 152.4 18.6 19.0 21 CEP209_CC5 Coiled-coil region of centrosome protein CE29 4.2e-05 24.3 14.1 4.2e-05 24.3 14.1 22.3 24 DUF7801 Domain of unknown function (DUF7801) 0.0015 19.6 5.0 0.0015 19.6 5.0 25.5 26 PRKG1_interact cGMP-dependent protein kinase interacting dom 0.0085 16.6 5.1 0.0085 16.6 5.1 22.9 23 CENP-F_leu_zip Leucine-rich repeats of kinetochore protein C Domain annotation for each model (and alignments): >> CEP209_CC5 Coiled-coil region of centrosome protein CE290 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 7.2 0.6 3.8e+03 72 115 .. 17 64 .. 10 76 .. 0.81 2 ? -4.0 3.5 3.4 2.1e+04 73 104 .. 146 177 .. 65 187 .. 0.56 3 ? -6.9 10.5 4 2.6e+04 21 113 .. 224 307 .. 195 320 .. 0.48 4 ? -1.4 1.4 0.52 3.3e+03 70 125 .. 325 375 .. 317 377 .. 0.52 5 ? -12.0 15.1 4 2.6e+04 49 49 .. 464 464 .. 415 559 .. 0.52 6 ? -0.8 14.5 0.35 2.2e+03 8 106 .. 631 731 .. 626 752 .. 0.82 7 ? -2.4 0.0 1.1 6.7e+03 27 49 .. 758 780 .. 734 786 .. 0.75 8 ? -7.9 13.9 4 2.6e+04 5 118 .. 798 915 .. 793 925 .. 0.69 9 ? -5.0 9.5 4 2.6e+04 12 110 .. 915 1013 .. 907 1031 .. 0.74 10 ! 152.4 18.6 1.4e-48 9e-45 1 128 [] 1090 1217 .. 1090 1217 .. 1.00 11 ! 4.4 1.5 0.0087 56 73 113 .. 1264 1304 .. 1251 1316 .. 0.62 12 ? -3.1 2.4 1.7 1.1e+04 88 125 .. 1350 1384 .. 1323 1404 .. 0.52 13 ? -10.5 11.8 4 2.6e+04 14 59 .. 1482 1521 .. 1465 1587 .. 0.39 14 ? -14.4 17.6 4 2.6e+04 48 123 .. 1586 1660 .. 1538 1672 .. 0.60 15 ? -14.2 17.7 4 2.6e+04 48 89 .. 1642 1687 .. 1587 1723 .. 0.47 16 ? -5.6 8.2 4 2.6e+04 56 96 .. 1731 1771 .. 1673 1780 .. 0.66 17 ? -2.1 3.6 0.87 5.5e+03 5 45 .. 1802 1843 .. 1798 1858 .. 0.77 18 ? -5.1 5.3 4 2.6e+04 5 59 .. 1877 1931 .. 1874 1938 .. 0.72 19 ? -11.5 15.2 4 2.6e+04 11 109 .. 2035 2129 .. 2019 2148 .. 0.46 20 ? -9.2 10.8 4 2.6e+04 3 90 .. 2095 2183 .. 2091 2226 .. 0.60 21 ? -3.4 1.9 2.2 1.4e+04 30 84 .. 2186 2240 .. 2158 2277 .. 0.57 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.6 CEP209_CC5 72 kknRelvkqkeeikylknlveeqertiss....leeeivqqnklqeer 115 kkn+el++ +ei+ l++ ++e e i++ lee ++nk+ ee+ FUN_001422-T1 17 KKNKELSEYLDEIRVLQEANDELEERIKDvqkeLEESTEEMNKMTEEC 64 89999****************999999752222677777788888875 PP == domain 2 score: -4.0 bits; conditional E-value: 3.4 CEP209_CC5 73 knRelvkqkeeikylknlveeqertissleee 104 + +l++ k ++ l++ v+e++ i+ l +e FUN_001422-T1 146 TGLQLDADKGSLAMLHQEVKEKDEKIEMLQKE 177 23344455555555555555555555555544 PP == domain 3 score: -6.9 bits; conditional E-value: 4 CEP209_CC5 21 eerrraedraqele....lklkgLeeLlst.lkDakGaqkvteWhkkleeirlqelkknRelvkqkeeikylknlveeqertissleeeivqqnkl 111 e+ ++ dr+ e lk k L++Lls ++ ++G ++e + +++ + q ++++++ +i+ l+ v++ e+ FUN_001422-T1 224 LESLEVKDRMIMAEeaaaLKDKQLNDLLSRmMQYERGEYGLSEAVQEIKDCKAQIRIRDQNIEDLTSQINNLEIEVNDAEM--------------E 305 222222222211111111555555555543133445555555555555555555444444555555555544444444444..............3 PP CEP209_CC5 112 qe 113 +e FUN_001422-T1 306 NE 307 33 PP == domain 4 score: -1.4 bits; conditional E-value: 0.52 CEP209_CC5 70 elkknRelvkqkeeikylknlveeqertissleeeivqqnklqeerqlawdqreve 125 ++++++++++ i+ + l+ + ++ leee +q+++ ++ l r ve FUN_001422-T1 325 DVRHKKKVKAE-QAIALNRALN----KEVERLEEERLQLKRQLRKQALHRGARAVE 375 44444443322.2233333333....335557777777777766666666666666 PP == domain 5 score: -12.0 bits; conditional E-value: 4 CEP209_CC5 49 D 49 + FUN_001422-T1 464 E 464 1 PP == domain 6 score: -0.8 bits; conditional E-value: 0.35 CEP209_CC5 8 dkakiqeeakkveeerrraedraqelelklkgLeeLlstl.kD.akGaqkvteWhkkleeirlqelkknRelvkqkeeikylknlveeqertissl 101 +k k ee++ +ee+ +e + ++l e Ll tl kD k ++++e +k+ +r+ e ++R ++++e l++ +++ + + FUN_001422-T1 631 EKEKWDEERRASDEEKASMELSREHDKIRLLEFERLLDTLdKDeDKQKKRLSEMARKVTVLRVNEKSLSRRYTAMQEVETALRKENKKFRNDVVAM 726 5677788888888888888888888889999*********54424777889*************************99999998888887777777 PP CEP209_CC5 102 eeeiv 106 e i FUN_001422-T1 727 ETAIS 731 77665 PP == domain 7 score: -2.4 bits; conditional E-value: 1.1 CEP209_CC5 27 edraqelelklkgLeeLlstlkD 49 +a+ele k +eL + +D FUN_001422-T1 758 SVQASELEAANKQYNELTAKYRD 780 45789999999999999988877 PP == domain 8 score: -7.9 bits; conditional E-value: 4 CEP209_CC5 5 LqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGa.......qkvteWhkkleeirlqelkknRelvkqkeeikylknlvee 93 L+ dk+ ++e ++++e + +r + le + L++Lls + Ga +++ +kl ++ ++el + ++ + l+ lv++ FUN_001422-T1 798 LEADKKLLEETEVELKKEMTALKERNHSLE---QMLNDLLSKDGGQGGAdtssvrqEEIDRISRKLATLEMKELNERERADHATRKYDQLQSLVQQ 890 555666666666666666666666666666...445555554444444422221213466678999999*****999999999999999******* PP CEP209_CC5 94 qertissleeeivqqnklqeerqla 118 e s+le + ++l+ e q + FUN_001422-T1 891 LEERNSELEHKFAEISNLNLESQRI 915 ************9999998777744 PP == domain 9 score: -5.0 bits; conditional E-value: 4 CEP209_CC5 12 iqeeakkveeerrraedraqelelklkgLeeLlstlk.DakGaqkvteWh.kkleeirlqelkknRelvkqkeeikylknlveeqertisslee 103 i++e ++ ++ e + + ++++Lee s lk ++ ++v e ++ e i+ q+ +++el+ + ++ y ++ ++ ++i +l FUN_001422-T1 915 IERELREELSNSVTQETH-LSVTRRVQSLEESESKLKvEVSRLKEVAEVAsHQTEAIKAQQESQDKELTSLRKQL-YDMQMENDDKTIIGKLHH 1006 444444443333333333.34556899999999999944566788999762578999**************9986.999999999999****** PP CEP209_CC5 104 eivqqnk 110 iv ++ FUN_001422-T1 1007 HIVALQV 1013 **98765 PP == domain 10 score: 152.4 bits; conditional E-value: 1.4e-48 CEP209_CC5 1 tmlkLqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGaqkvteWhkkleeirlqelkknRelvkqkeeikylknlveeq 94 tm +L++dk+ +++e kk++++r+ aedr+ el l++ gL+eL++tlkD+kGa+kvteWh k+ e+rlq+lk+nR +++ +ee+kyl+n+v+ + FUN_001422-T1 1090 TMRTLHDDKRTLERELKKAKNDREAAEDRLAELKLQHDGLQELMATLKDGKGAAKVTEWHAKMGELRLQDLKLNRAVTRLQEELKYLENVVKVH 1183 89******************************************************************************************** PP CEP209_CC5 95 ertissleeeivqqnklqeerqlawdqreveleR 128 er is+le+e vq+ k +e+rql+w+qreveleR FUN_001422-T1 1184 ERSISDLEDENVQMAKEHEDRQLIWEQREVELER 1217 *********************************9 PP == domain 11 score: 4.4 bits; conditional E-value: 0.0087 CEP209_CC5 73 knRelvkqkeeikylknlveeqertissleeeivqqnklqe 113 + R++v +ee+k lk+ +e + + ++ ee + q+ kl + FUN_001422-T1 1264 HIRTIVGTREENKQLKKKHNELDLAFKQSEERLTQKDKLIN 1304 23666666666666666666666666666666666666655 PP == domain 12 score: -3.1 bits; conditional E-value: 1.7 CEP209_CC5 88 knlveeqertissleeeivqqnklqeerqlawdqreve 125 +++ +++e ++++ +++ +ee + + +q +ve FUN_001422-T1 1350 QQMLAHKEESLNKYQAM---LKEAREEAKTQSEQHKVE 1384 44444444443333321...222233333333333333 PP == domain 13 score: -10.5 bits; conditional E-value: 4 CEP209_CC5 14 eeakkveeerrraedraqelelklkgLeeLlstlkDakGaqk.vteW 59 +e kk++ e+ + ++r++e ++ lkD+ ++k e FUN_001422-T1 1482 NELKKITSEKMERDERIME-------QSKMIEVLKDELETAKeAAER 1521 3334444444444444444.......444444444443322202222 PP == domain 14 score: -14.4 bits; conditional E-value: 4 CEP209_CC5 48 kDakGaq.kvteWhkkleeirlqelkknRelvkq.keeikylknlveeqertissleeeivqqnklqeerqlawdqre 123 k++ G q ++ e ++++e+ + +el+k+R+ ++ e lk+ ++++ ++ ++ e+ +++++qe ql+ +++e FUN_001422-T1 1586 KETTGLQsRIEELQERMEKFK-KELRKQRDKETAlLGEKDKLKQDLSKKDAALLKFGRELKELETVQE--QLEKKDQE 1660 334443326778888888887.7888888654431344444555556677777777777777777765..44444444 PP == domain 15 score: -14.2 bits; conditional E-value: 4 CEP209_CC5 48 kDakGaqkvteWh.kkleeirlqelkknR...elvkqkeeikylkn 89 ++ k + v e kk +e+r+ k+ + e+++ +e++k l++ FUN_001422-T1 1642 RELKELETVQEQLeKKDQELRIEKNKHAQersEIENLREKVKSLQE 1687 2223333333322033344444443332111134444444444433 PP == domain 16 score: -5.6 bits; conditional E-value: 4 CEP209_CC5 56 vteWhkkleeirlqelkknRelvkqkeeikylknlveeqer 96 W++k+e+++ + k+Rel+k + ++ l++ + e+ FUN_001422-T1 1731 NKKWQQKVETLKGKLAEKTRELEKAQKSNAMLREALNRAEK 1771 46799999999999999999999988888888877776665 PP == domain 17 score: -2.1 bits; conditional E-value: 0.87 CEP209_CC5 5 Lqedkakiqeeakkveeerrraedraqe.lelklkgLeeLls 45 L+ k++ee +++++e+ d+ +e lel+ + e + FUN_001422-T1 1802 LKHSIFKLEEENQELRREKVLGHDKQMEaLELRNRQQMEYIG 1843 666777899999999999999888877768999887666655 PP == domain 18 score: -5.1 bits; conditional E-value: 4 CEP209_CC5 5 LqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGaqkvteW 59 Lq++ ++++ee +++ e ++a + l +++ L+e + lk + a k e FUN_001422-T1 1877 LQKQLLEVKEENMELRFEYEQARKENPRLKARVEDLQEYVEILKAELEASKKREK 1931 6666677777777777777777777788888888888888888877777666655 PP == domain 19 score: -11.5 bits; conditional E-value: 4 CEP209_CC5 11 kiqeeakkveeerrraedraqelelklkgLeeLlstlkD.akGaqkvteWhk....kl..eeirlqelkknRelvkqkeeikylknl.veeqer 96 k ee++k++ + ++e+r ++l ++ +e+L + l + + G+ eW k+ e++r e ++++ + k+ ylk ++e e FUN_001422-T1 2035 KEMEEVEKLKAANANLEQRKEDL---VREMEQLQQKLTNsNMGTLDSKEWKSvvlpKIyeEKMRKLEAELEKKTNLLKDIKTYLKAAaNRETEL 2125 22334444444444444444444...34445555555441457777777764222233112333333344455555555555665441233343 PP CEP209_CC5 97 tissleeeivqqn 109 t + + FUN_001422-T1 2126 TNK---------Q 2129 332.........2 PP == domain 20 score: -9.2 bits; conditional E-value: 4 CEP209_CC5 3 lkLqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGaqkv.teWhkkleeirlqelkknRelvkqkeeikylknl 90 kL+ + k + k +++ + a +r +el k++ Lee ++ l+ k ++ k ++++rl+ ++ e ++ e++ l+++ FUN_001422-T1 2095 RKLEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELEEKVAILERFPTNIKSdSDLVKEFQQTRLRVATLESEKEEILHEVRQLRKM 2183 55555555555556666677778888888888888888888888876544333214555666666665555555555555555555555 PP == domain 21 score: -3.4 bits; conditional E-value: 2.2 CEP209_CC5 30 aqelelklkgLeeLlstlkDakGaqkvteWhkkleeirlqelkknRelvkqkeei 84 a +l l++ e L + +k k +e ++l+++ l +++ e++k + e+ FUN_001422-T1 2186 AGDLPRDLENDEVLEKLIKYDKMMTDDVELRTRLKTVELERDRLSHEITKLRKEL 2240 4444444444444444455555555556777777777777777777777766554 PP >> DUF7801 Domain of unknown function (DUF7801) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 14.1 6.6e-09 4.2e-05 63 152 .. 13 98 .. 7 100 .. 0.93 2 ? 2.6 6.2 0.031 2e+02 56 111 .. 125 185 .. 115 196 .. 0.75 3 ? -6.6 12.9 4 2.6e+04 3 90 .. 164 253 .. 162 306 .. 0.50 4 ? -8.2 16.3 4 2.6e+04 7 142 .. 289 437 .. 282 439 .. 0.58 5 ? -1.6 5.7 0.59 3.8e+03 64 109 .. 415 460 .. 400 473 .. 0.70 6 ! 7.7 3.7 0.00084 5.4 57 105 .. 502 550 .. 490 557 .. 0.89 7 ? -2.1 5.9 0.85 5.4e+03 54 128 .. 647 719 .. 636 723 .. 0.71 8 ? -4.7 12.9 4 2.6e+04 48 143 .. 720 820 .. 707 834 .. 0.64 9 ? -0.1 12.1 0.21 1.3e+03 57 148 .. 811 904 .. 807 906 .. 0.78 10 ? -1.1 9.7 0.42 2.7e+03 56 131 .. 847 926 .. 840 929 .. 0.67 11 ? 1.8 5.5 0.053 3.4e+02 57 110 .. 934 987 .. 926 996 .. 0.82 12 ? -7.3 10.6 4 2.6e+04 78 147 .. 1042 1106 .. 1009 1125 .. 0.48 13 ? -0.8 3.2 0.35 2.2e+03 58 110 .. 1087 1138 .. 1078 1147 .. 0.73 14 ? -0.1 11.4 0.21 1.4e+03 57 142 .. 1147 1229 .. 1138 1238 .. 0.83 15 ? -3.6 10.1 2.6 1.6e+04 47 105 .. 1336 1393 .. 1288 1401 .. 0.78 16 ? -6.6 14.0 4 2.6e+04 59 107 .. 1467 1515 .. 1435 1535 .. 0.74 17 ? -6.6 31.7 4 2.6e+04 8 151 .. 1536 1694 .. 1530 1698 .. 0.72 18 ? 0.3 2.5 0.16 1e+03 88 117 .. 1729 1758 .. 1710 1783 .. 0.56 19 ? -8.0 12.6 4 2.6e+04 9 98 .. 1737 1838 .. 1729 1869 .. 0.48 20 ? 2.9 13.2 0.025 1.6e+02 46 127 .. 1850 1931 .. 1847 1966 .. 0.84 21 ? 2.7 6.5 0.029 1.9e+02 11 106 .. 1896 1997 .. 1894 2001 .. 0.83 22 ? -3.1 14.8 1.7 1.1e+04 35 106 .. 1992 2070 .. 1982 2110 .. 0.69 23 ? -1.6 2.7 0.59 3.8e+03 65 102 .. 2097 2134 .. 2078 2158 .. 0.54 24 ! 5.2 8.2 0.0047 30 61 146 .. 2162 2247 .. 2149 2253 .. 0.80 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 6.6e-09 DUF7801 63 deLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaqlsdekvk 152 d+L++kn+el+e l++++ +e ++ el+er+k ++kEL+e +ee +++t + +l ++ + +iD++r++ ++L aq++d +++ FUN_001422-T1 13 DKLSKKNKELSEYLDEIRVLQE----ANDELEERIKDVQKELEESTEEMNKMTEECTKLKTILQQSDLIIDDMRKERDALRAQVQDLRMQ 98 89***************98765....567899******************************************************9987 PP == domain 2 score: 2.6 bits; conditional E-value: 0.031 DUF7801 56 paiqkeldeLkaknaeleeelaaLkaekeak.....eaesaelqervkaLekELretieey 111 +a + el++ k+ +el+++++ L+ + ++ ++e +e++e++++L+kEL++ ++e FUN_001422-T1 125 AAKEIELEQYKSLVEELQQQITGLQLDADKGslamlHQEVKEKDEKIEMLQKELEKAASEM 185 45567888999999999999999886554331222256778999***********998886 PP == domain 3 score: -6.6 bits; conditional E-value: 4 DUF7801 3 reeaeeeleklekEleelesevvrlqteltlakA....eLdgAYGsraeRaaevaanpaiq.keldeLkaknael.eeelaaLkaekeakeaes 90 +e++e++e l+kEle++ se+ + +k+ +AY + R +e n+++q ++l++L+ k++ + +ee aaLk ++ ++ ++ FUN_001422-T1 164 VKEKDEKIEMLQKELEKAASEMHGVASYAEQVKSlsekGVPSAYQQK--RIKEL--NSTLQrEQLESLEVKDRMImAEEAAALKDKQLNDLLSR 253 45677778888888888888777666555555541100344444333..55554..44444145788887776541577777877664443333 PP == domain 4 score: -8.2 bits; conditional E-value: 4 DUF7801 7 eeeleklekEleelesevvrlqteltla.kAeLdgA...YGsraeRaaevaanpaiqkeldeLkaknaeleeelaa..Lkaekeakeae..s.... 90 ++++++le E++++e+e l+ l + k Ld + + + + +a+n a++ke+++L+++ +l+++l + L++ +a e + + FUN_001422-T1 289 TSQINNLEIEVNDAEMENEELRERLGMDpKEKLDIEdvrHKKKVKAEQAIALNRALNKEVERLEEERLQLKRQLRKqaLHRGARAVELGitAedli 384 6778889999999999999999999995355566431113334344445689*******************9986411444333222111010111 PP DUF7801 91 aelqervkaLekELretieeyeeltkas.ielEkeRekleeliDslrdrceqL 142 +e+v + L + ++ e+tka +lE e ek e+ i +++ ++ ++ FUN_001422-T1 385 MAEEENVVSAPRRLPHATDSDSEVTKAVnKRLEGEVEKSEQQIEKFKTNMKKI 437 12233333444556666666666666531345666666666666666666555 PP == domain 5 score: -1.6 bits; conditional E-value: 0.59 DUF7801 64 eLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretie 109 +L+ + ++ e++++++k++ ++ e+e++el+++ k+Le +re+++ FUN_001422-T1 415 RLEGEVEKSEQQIEKFKTNMKKIESENKELKDENKQLEVGMREILA 460 4555556667778888888888888888888888888887777765 PP == domain 6 score: 7.7 bits; conditional E-value: 0.00084 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELr 105 ++++++++L+ +n+el +el++ ++e++++ ++ + ++ +++ LekE + FUN_001422-T1 502 QLKAQIEQLSGRNEELRHELHNAREETAKAVMQVERKNTKIEDLEKEVQ 550 67899********************9999999999999*********87 PP == domain 7 score: -2.1 bits; conditional E-value: 0.85 DUF7801 54 anpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekl 128 a ++++e d++ + e+e+ l++L +++++++++ +e++++v++L+ + + + y ++ l ke +k+ FUN_001422-T1 647 ASMELSREHDKI--RLLEFERLLDTLDKDEDKQKKRLSEMARKVTVLRVNEKSLSRRYTAMQEVETALRKENKKF 719 444555666655..4456677788999988888888899999999999888888888888888777777777766 PP == domain 8 score: -4.7 bits; conditional E-value: 4 DUF7801 48 RaaevaanpaiqkeldeLkaknaeleeelaaLkaekeak.eaes.aelqervkaLekELretie.eyeeltkasi..elEkeRekleeliDslrdr 138 R va++ ai++ l L+++++ + ++++L+++ +++ +a++ + ++++ + L r++i+ e +++++i lE +++ lee+ +l+++ FUN_001422-T1 720 RNDVVAMETAISERLGYLQRHKEMSTYKISVLQQALDESvQASElEAANKQYNELTAKYRDIIQrENSLVARSAIvdSLEADKKLLEETEVELKKE 815 666788899999999999888888889999998876544133331445567788888889888635555677777444677777777664444444 PP DUF7801 139 ceqLe 143 + +L FUN_001422-T1 816 MTALK 820 44332 PP == domain 9 score: -0.1 bits; conditional E-value: 0.21 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeak..eaesaelqervkaLekELret.ieeyeeltkasielEkeRekleeliDslrdrceqLeaqlsd 148 +++ke+ +Lk++n++le+ l+ L ++ + +++s+ qe+++ + + L+ + ++e +e +a ++ + ++l++l+ +l +r +Le ++++ FUN_001422-T1 811 ELKKEMTALKERNHSLEQMLNDLLSKDGGQggADTSSVRQEEIDRISRKLATLeMKELNERERAD-HATRKYDQLQSLVQQLEERNSELEHKFAE 904 689*******************9887654411344556688889999999865367777766665.4556789*****************99876 PP == domain 10 score: -1.1 bits; conditional E-value: 0.42 DUF7801 56 paiqkeldeLkaknaele.eelaaLkaekeakeaesaelqervkaLe...kELretieeyeeltkasielEke.Rekleel 131 ++ q+e+d++++k a+le +el++ ++ ++++++ +lq+ v++Le +EL++ +e +l +s ++E+e Re+l + FUN_001422-T1 847 SVRQEEIDRISRKLATLEmKELNER-ERADHATRKYDQLQSLVQQLEernSELEHKFAEISNLNLESQRIERElREELSNS 926 5679999999999888853444442.2233344455667777777762225888888888888888888888877777665 PP == domain 11 score: 1.8 bits; conditional E-value: 0.053 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretiee 110 ++++ +++L++++++l+ e++ Lk+ e ++++++ ++ +++ kEL+ + ++ FUN_001422-T1 934 SVTRRVQSLEESESKLKVEVSRLKEVAEVASHQTEAIKAQQESQDKELTSLRKQ 987 5678999*****************999888888888888888888998876655 PP == domain 12 score: -7.3 bits; conditional E-value: 4 DUF7801 78 aLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaqls 147 ++ ++ +a +++ e+++++k L+k ++++ ++y ++ l k ek+ e++ +l+d++ +Le +l FUN_001422-T1 1042 KIDEKDQALYHAKMEARNKAKFLKKTIQDLRRQYS----GALPLMK-QEKFAETMRTLHDDKRTLERELK 1106 23333333344555666666666666666665554....3444433.24444444455555555554443 PP == domain 13 score: -0.8 bits; conditional E-value: 0.35 DUF7801 58 iqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretiee 110 + + +L++ +++le+el++ k+++ea+e++ ael+ + + L+ EL +t+++ FUN_001422-T1 1087 FAETMRTLHDDKRTLERELKKAKNDREAAEDRLAELKLQHDGLQ-ELMATLKD 1138 45667778888888888888888888888888888777777774.66666655 PP == domain 14 score: -0.1 bits; conditional E-value: 0.21 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqL 142 + ++++ eL+ ++ +l++ ++ L++e + e+ + +++ ++ Le E ++++e+e+ + +E+ +le++iD+l ++ +L FUN_001422-T1 1147 EWHAKMGELRLQDLKLNRAVTRLQEELKYLENVVKVHERSISDLEDENVQMAKEHED---RQLIWEQREVELERMIDKLEKQQREL 1229 5677888999999999999***999998888888888888999***********997...45669999999********8877666 PP == domain 15 score: -3.6 bits; conditional E-value: 2.6 DUF7801 47 eRaaevaanpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELr 105 +Ra +va +++++ + L++k+++l++ a+Lk+++e+++++s++++ +++ L+ L+ FUN_001422-T1 1336 KRALKVAQ-ATVSSLQQMLAHKEESLNKYQAMLKEAREEAKTQSEQHKVEIQLLQDRLH 1393 36776664.34555557788999999999999999999999999888888888887775 PP == domain 16 score: -6.6 bits; conditional E-value: 4 DUF7801 59 qkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELret 107 ++ +++++k++e ++el+++++ek +++++ e+++ +++L+ EL+ FUN_001422-T1 1467 ENFKQQMTRKDEEHSNELKKITSEKMERDERIMEQSKMIEVLKDELETA 1515 3333567778888899999999999999999999999999999999765 PP == domain 17 score: -6.6 bits; conditional E-value: 4 DUF7801 8 eeleklekEleelesevvrlqteltlakAeLdgAYGsraeRaaevaa.....npaiqkeldeLkaknaeleeelaaLkaekea....keaesae 92 ++l+ +ek ++l++ + +l++++ + e A+ rae +a+v+ +q+ ++eL+++ +++++el + + +++a k++ +++ FUN_001422-T1 1536 NQLALKEKQQKSLSQALLQLRADMVSTAEENVQAHARRAEEQANVQHvvdkeTTGLQSRIEELQERMEKFKKELRKQRDKETAllgeKDKLKQD 1629 566667778888999999999998777777778999***9999997422222456778888888888888888887776654311113444566 PP DUF7801 93 lqervkaLe...kELretieeyeeltka..sielEkeRekle.eliDslrdrceqLeaqlsdekv 151 l+++ aL +EL+e+ + e+l k+ +++Ek+++ e + i +lr+++ +L+++l +e+ FUN_001422-T1 1630 LSKKDAALLkfgRELKELETVQEQLEKKdqELRIEKNKHAQErSEIENLREKVKSLQEKLKQERK 1694 666666553133799999888889988622677899998888357****************9995 PP == domain 18 score: 0.3 bits; conditional E-value: 0.16 DUF7801 88 aesaelqervkaLekELretieeyeeltka 117 +++++ q++v++L+ L+e ++e e+ k+ FUN_001422-T1 1729 EDNKKWQQKVETLKGKLAEKTRELEKAQKS 1758 445555555555555555555555543332 PP == domain 19 score: -8.0 bits; conditional E-value: 4 DUF7801 9 eleklekEleelesevvrlqteltl.....akAeLdgA.YGsraeRaaevaa.np..aiqkeldeLkaknaeleeelaaLkaek...eakeaes 90 ++e+l+ l+e e+ ++q ++ +Ae d A sr + ++++ +p ++++ +++Lk++ +leee ++L++ek ++k++e+ FUN_001422-T1 1737 KVETLKGKLAEKTRELEKAQKSNAMlrealNRAEKDKAgLHSRLKSSVKAGVvEPsvVTNEVVQDLKHSIFKLEEENQELRREKvlgHDKQMEA 1830 4444444444444444444444333000004555555423344333333222133113445567888888888888888887763333334444 PP DUF7801 91 aelqervk 98 el++r++ FUN_001422-T1 1831 LELRNRQQ 1838 44555444 PP == domain 20 score: 2.9 bits; conditional E-value: 0.025 DUF7801 46 aeRaaev.aanpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRek 127 aeRaae + + a + eL+++n+ l+++l ++k+e+ + + e ++++++ L+ ++ ++ey e+ ka +e+ k Rek FUN_001422-T1 1850 AERAAEErSFDRADADMYRELHQRNQYLQKQLLEVKEENMELRFEYEQARKENPRLKARVED-LQEYVEILKAELEASKKREK 1931 78888762456666667789999999999999999999988888888888888999998877.58899999999999999987 PP == domain 21 score: 2.7 bits; conditional E-value: 0.029 DUF7801 11 eklekEleelesevvrlqteltlakAeLdgAYGsraeRaaeva......anpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervk 98 e+++kE l++ v lq + + kAeL++ + R+++ + + +++ + ++++ ++l+ e ++Lk++ a + + e+ ++ k FUN_001422-T1 1896 EQARKENPRLKARVEDLQEYVEILKAELEASKKREKARKKNLGtgmggqSVEDMERVIAAMRRVVERLQGENDQLKKSVGAGGPQYGEVIKENK 1989 788999999*********************9999999999986222222345566777888888889999999999999999999999999*** PP DUF7801 99 aLekELre 106 L++EL + FUN_001422-T1 1990 RLKQELDK 1997 *****975 PP == domain 22 score: -3.1 bits; conditional E-value: 1.7 DUF7801 35 kAeLdgAYGs......raeRaaevaanp.aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELre 106 k eLd A G+ ++ R +++an ++ +e ++L ++ ++ ee+++Lka++++ e+++++l +++++L++ L++ FUN_001422-T1 1992 KQELDKAKGAsvktggQSSRGVNASANTtKLMAENEKLLKNLKKEMEEVEKLKAANANLEQRKEDLVREMEQLQQKLTN 2070 4555555544111111556666666554145667777766666666788888888888888888888888888887765 PP == domain 23 score: -1.6 bits; conditional E-value: 0.59 DUF7801 65 LkaknaeleeelaaLkaekeakeaesaelqervkaLek 102 L+a+ ++ ++ l+ +k+ +a++++++el+++++ Le+ FUN_001422-T1 2097 LEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELEE 2134 33333333333333333333334444444444444433 PP == domain 24 score: 5.2 bits; conditional E-value: 0.0047 DUF7801 61 eldeLkaknaeleeelaaLkaekeak.eaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaql 146 + +L+++++e+ +e+ +L++ +a ++ e +e ++L k + ++++ e t+ +E eR++l + i +lr++ e+++ + FUN_001422-T1 2162 RVATLESEKEEILHEVRQLRKMGQAGdLPRDLENDEVLEKLIKYDKMMTDDVELRTRLK-TVELERDRLSHEITKLRKELEAFDPAF 2247 578999**************976655145677788888889888899999999999964.456677789999*********988665 PP >> PRKG1_interact cGMP-dependent protein kinase interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.1 9.0 0.0075 48 10 72 .. 33 99 .. 24 104 .. 0.80 2 ! 5.7 2.6 0.0052 33 8 76 .. 80 149 .. 73 157 .. 0.91 3 ? -4.3 11.4 4 2.6e+04 18 91 .. 162 240 .. 133 251 .. 0.50 4 ? -1.4 8.4 0.82 5.2e+03 8 91 .. 301 357 .. 263 370 .. 0.55 5 ! 6.7 5.0 0.0026 16 11 53 .. 411 453 .. 383 467 .. 0.63 6 ! 5.0 1.7 0.0082 52 4 50 .. 505 551 .. 498 559 .. 0.70 7 ? -2.5 4.0 1.8 1.2e+04 22 74 .. 595 650 .. 580 668 .. 0.63 8 ? -7.2 13.0 4 2.6e+04 22 92 .. 662 726 .. 624 735 .. 0.52 9 ! 5.5 6.3 0.0058 37 17 77 .. 761 821 .. 745 834 .. 0.83 10 ? -2.8 9.3 2.3 1.5e+04 16 88 .. 856 918 .. 844 925 .. 0.53 11 ? 0.1 9.0 0.28 1.8e+03 17 71 .. 936 994 .. 922 1006 .. 0.73 12 ? -0.9 3.4 0.58 3.7e+03 18 71 .. 1020 1074 .. 1010 1086 .. 0.80 13 ? -0.0 7.7 0.31 2e+03 8 80 .. 1056 1134 .. 1047 1144 .. 0.68 14 ? -2.9 10.3 2.4 1.5e+04 14 89 .. 1099 1194 .. 1086 1199 .. 0.64 15 ? 3.3 9.6 0.029 1.8e+02 5 88 .. 1207 1305 .. 1203 1308 .. 0.83 16 ? -3.8 7.4 4 2.6e+04 12 66 .. 1331 1383 .. 1319 1399 .. 0.55 17 ? -5.2 14.8 4 2.6e+04 12 76 .. 1451 1516 .. 1440 1529 .. 0.66 18 ? -2.3 13.2 1.6 1e+04 14 81 .. 1532 1612 .. 1521 1620 .. 0.60 19 ? -4.0 16.6 4 2.6e+04 11 82 .. 1621 1693 .. 1617 1701 .. 0.81 20 ? -2.9 10.2 2.4 1.6e+04 12 92 .. 1730 1816 .. 1726 1820 .. 0.48 21 ? -6.2 11.6 4 2.6e+04 8 89 .. 1808 1888 .. 1794 1894 .. 0.40 22 ! 19.6 5.0 2.3e-07 0.0015 5 90 .. 1894 1975 .. 1890 1976 .. 0.91 23 ? 3.4 11.2 0.026 1.7e+02 6 98 .. 1981 2063 .. 1979 2066 .. 0.70 24 ? -6.4 16.5 4 2.6e+04 12 78 .. 2025 2107 .. 2018 2123 .. 0.53 25 ? -4.9 8.3 4 2.6e+04 14 52 .. 2095 2133 .. 2086 2194 .. 0.54 26 ? 0.4 1.7 0.23 1.5e+03 6 42 .. 2205 2241 .. 2199 2279 .. 0.71 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0075 PRKG1_interact 10 lqenerLkekleelkkelaeiksklekvkq...kqesl.skrssllelekrEkralerkiseleeel 72 ++ n++L e++++++kel+e++++++k+++ k + + +++ +++ ++E+ al ++++l ++ FUN_001422-T1 33 QEANDELEERIKDVQKELEESTEEMNKMTEectKLKTIlQQSDLIIDDMRKERDALRAQVQDLRMQF 99 56799***********************95355555551445556677899**********998776 PP == domain 2 score: 5.7 bits; conditional E-value: 0.0052 PRKG1_interact 8 kalqenerLkekleelkkelaeiksklekvk.qkqeslskrssllelekrEkralerkiseleeelkvle 76 + ++e + L+ ++++l+++ a+ + + + + + ++++ +++l +++ E ++++ + el++++ l+ FUN_001422-T1 80 DMRKERDALRAQVQDLRMQFANKTDTDDDIMvAVNAKVEEWKAVLAAKEIELEQYKSLVEELQQQITGLQ 149 67999******************99999999557889***************************998775 PP == domain 3 score: -4.3 bits; conditional E-value: 4 PRKG1_interact 18 ekleelkkelaeiksklekvkqkqe...slskrssllelekrEkralerkiseleeelk..vleeLkaeNqrLkdENgA 91 ++++e +++++ ++++lek++++ + s +++ + l+ + + +++i el++ l+ +le+L ++ + +E +A FUN_001422-T1 162 QEVKEKDEKIEMLQKELEKAASEMHgvaSYAEQVKSLSEKGVPSAYQQKRIKELNSTLQreQLESLEVKDRMIMAEEAA 240 4444444444444444444442221222444444444444445555566666666655322555666555555555444 PP == domain 4 score: -1.4 bits; conditional E-value: 0.82 PRKG1_interact 8 kalqenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgA 91 +a ene+L+e+l ke+ +i+ +k k + e+ + ++L +e +rL +E FUN_001422-T1 301 DAEMENEELRERLGMDPKEKLDIEDVRHKKK---------------------------VKAEQAIALNRALNKEVERLEEERLQ 357 4455666666666554444444443333333...........................33333333333333333333333322 PP == domain 5 score: 6.7 bits; conditional E-value: 0.0026 PRKG1_interact 11 qenerLkekleelkkelaeiksklekvkqkqeslskrssllel 53 + n+rL ++e++++++++ k++++k+++++++l+++++ le+ FUN_001422-T1 411 AVNKRLEGEVEKSEQQIEKFKTNMKKIESENKELKDENKQLEV 453 3455555555555555555555555555555555555555555 PP == domain 6 score: 5.0 bits; conditional E-value: 0.0082 PRKG1_interact 4 klyekalqenerLkekleelkkelaeiksklekvkqkqeslskrssl 50 + e+ ne+L+++l+++++e a+ +++e+ + k e l+k+ ++ FUN_001422-T1 505 AQIEQLSGRNEELRHELHNAREETAKAVMQVERKNTKIEDLEKEVQV 551 44566666788888888888888888888888877666666655444 PP == domain 7 score: -2.5 bits; conditional E-value: 1.8 PRKG1_interact 22 elkkelaeiksklekvkqkqeslskrssllele...krEkralerkiseleeelkv 74 ++ la++++ le k k + +++ ll ++ ++Ek+ er++s+ e+ + FUN_001422-T1 595 LKEELLAKMEKDLELFKRKVSVILHQKGLLYADylrEKEKWDEERRASDEEKASME 650 33445666777777776666655555555544322278999999999998876544 PP == domain 8 score: -7.2 bits; conditional E-value: 4 PRKG1_interact 22 elkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgAL 92 e ++ l+++ + +k k++ +++++ + + + +++l r+ + ++e v ++L++eN++ +++ A+ FUN_001422-T1 662 EFERLLDTLDKDEDKQKKRLSEMARKVT---VLRVNEKSLSRRYTAMQE---VETALRKENKKFRNDVVAM 726 3333333333333333333333333333...333344566666666654...4556666666666655555 PP == domain 9 score: 5.5 bits; conditional E-value: 0.0058 PRKG1_interact 17 kekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvlee 77 ++le ++k+ +e+++k + q+++sl +rs++++ + +k+ le +el++e+ +l+e FUN_001422-T1 761 ASELEAANKQYNELTAKYRDIIQRENSLVARSAIVDSLEADKKLLEETEVELKKEMTALKE 821 5799********************************************9999999987765 PP == domain 10 score: -2.8 bits; conditional E-value: 2.3 PRKG1_interact 16 LkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdE 88 + +kl +l+++ +++++ ++++ + + ++le + sele+++ +++L e qr+ E FUN_001422-T1 856 ISRKLATLEMKELNERERADHAT----------RKYDQLQSLVQQLEERNSELEHKFAEISNLNLESQRIERE 918 33333333333333333333332..........2222223334677777777888888888888777776655 PP == domain 11 score: 0.1 bits; conditional E-value: 0.28 PRKG1_interact 17 kekleelkkelaeiksklekvkq....kqeslskrssllelekrEkralerkiseleee 71 +++++l+++ +++k++++++k+ ++++++ ++ e +++E +l +++ +++ e FUN_001422-T1 936 TRRVQSLEESESKLKVEVSRLKEvaevASHQTEAIKAQQESQDKELTSLRKQLYDMQME 994 46667777777777777666664233355678888899999999*********999977 PP == domain 12 score: -0.9 bits; conditional E-value: 0.58 PRKG1_interact 18 ekleelkkelaeiksklekvkqkqeslskrssllelekrEkra.lerkiseleee 71 +kle + ++l+++++ + +++qk ++ ++ +++e r k + l++ i++l ++ FUN_001422-T1 1020 RKLEAATQKLSRQEALVLRLEQKIDEKDQALYHAKMEARNKAKfLKKTIQDLRRQ 1074 7899999999999999999999999999999999999888866256667777665 PP == domain 13 score: -0.0 bits; conditional E-value: 0.31 PRKG1_interact 8 kalqenerLkekleelkkelaeik..sklekvkq..kqeslskrssl..lelekrEkralerkiseleeelkvleeLka 80 +a+++++ Lk+ +++l+++ + +k ek ++ ++ + +kr+ l+ k++++a e +++el+ + l+eL a FUN_001422-T1 1056 EARNKAKFLKKTIQDLRRQYSGALplMKQEKFAEtmRTLHDDKRTLEreLKKAKNDREAAEDRLAELKLQHDGLQELMA 1134 6788889999*****999988765113444444323333444444431144568899*************999999975 PP == domain 14 score: -2.9 bits; conditional E-value: 2.4 PRKG1_interact 14 erLkekleelkkelaeiksklekvk.qkqe................slskrssllelekrEkralerkiseleeelkvleeLkaeNqr....L 85 ++L ++l+++k++ + + +l ++k q ++ ++++ + + + +l+r ++ l+eelk le++ + +r L FUN_001422-T1 1099 RTLERELKKAKNDREAAEDRLAELKlQ-HDglqelmatlkdgkgaaKVTEWHAKMGELRLQDLKLNRAVTRLQEELKYLENVVKVHERsisdL 1190 556666666666666666666665533.22344455555555555577777777766777888999*************99865544433336 PP PRKG1_interact 86 kdEN 89 dEN FUN_001422-T1 1191 EDEN 1194 7777 PP == domain 15 score: 3.3 bits; conditional E-value: 0.029 PRKG1_interact 5 lyekalqenerLkekleelkkelaeiksklekvk.qkqe..............slskrssllelekrEkralerkiseleeelkvleeLkaeN 82 ++e+ e er+ +kle+ ++elae ++k+e+++ + + +++++ ++ ++E+++l++k el+ +k+ ee ++ FUN_001422-T1 1207 IWEQREVELERMIDKLEKQQRELAEAATKFEEATgSIPDpnlpvanqlemaisKIKEHIRTIVGTREENKQLKKKHNELDLAFKQSEERLTQK 1299 799999**************************9954233667777788888877777778888889999999999999999999998877777 PP PRKG1_interact 83 qrLkdE 88 ++L +E FUN_001422-T1 1300 DKLINE 1305 777666 PP == domain 16 score: -3.8 bits; conditional E-value: 4 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkr.alerkis 66 en + k+ l+ ++ ++++++ l + k+esl+k +++l+ ++E + + e++ + FUN_001422-T1 1331 ENYETKRALKVAQATVSSLQQMLAH---KEESLNKYQAMLKEAREEAKtQSEQHKV 1383 4444444444444444444433333...6678888888777666664413344433 PP == domain 17 score: -5.2 bits; conditional E-value: 4 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkise.leeelkvle 76 ++ +e +e ++++++ k+++ + ++++ + k+ + ++e+ E+ + k++e l++el++ + FUN_001422-T1 1451 SRNEVMETKKEHEEDVENFKQQMTRKDEEHSNELKKITSEKMERDERIMEQSKMIEvLKDELETAK 1516 333344444566667777777777766666667777777788888888777777773566666655 PP == domain 18 score: -2.3 bits; conditional E-value: 1.6 PRKG1_interact 14 erLkekleelkkelaeiksklekvkq....kqe.........slskrssllelekrEkralerkiseleeelkvl.eeLkae 81 erL+++l +k+++++ + l +++ + +++ + ++ ++E l+ +i el+e ++++ +eL+++ FUN_001422-T1 1532 ERLRNQLALKEKQQKSLSQALLQLRAdmvsT-AeenvqaharRAEEQANVQHVVDKETTGLQSRIEELQERMEKFkKELRKQ 1612 4555554443333333333333332111110.0223334444889999999999***************9997761456654 PP == domain 19 score: -4.0 bits; conditional E-value: 4 PRKG1_interact 11 qenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvlee.LkaeN 82 e ++Lk+ l + + l + +l++++ qe+l+k+ + l +ek+ + + i +l e++k l+e Lk+e FUN_001422-T1 1621 GEKDKLKQDLSKKDAALLKFGRELKELETVQEQLEKKDQELRIEKNKHAQERSEIENLREKVKSLQEkLKQER 1693 6889999999999999999999999999889999999999999998777777788899999998874366665 PP == domain 20 score: -2.9 bits; conditional E-value: 2.4 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelek.....rEkralerkiseleeel...kvleeLkaeNqrLkdENgAL 92 +n++ ++k+e+lk +lae + +lek+++++ l + +e +k r k +++ + +e ++ +v+++Lk +L +EN+ L FUN_001422-T1 1730 DNKKWQQKVETLKGKLAEKTRELEKAQKSNAMLREALNRAEKDKaglhsRLKSSVKAGV--VEPSVvtnEVVQDLKHSIFKLEEENQEL 1816 67777777777777777777777776543332222222222222000002222222223..3332211255666776666666666655 PP == domain 21 score: -6.2 bits; conditional E-value: 4 PRKG1_interact 8 kalqenerLkek.leelkkelaeiksklekvkqkqe....slskrssllelekrEkralerkiseleeelkvlee.LkaeNqrLkdEN 89 k +en++L+++ + +++e ++ +++ + + + l E+r+ +r +++ +el++ ++ L+++ k+EN FUN_001422-T1 1808 KLEEENQELRREkVLG-------HDKQMEALELRNRqqmeYIGRLERDLAERAAEERSFDRADADMYRELHQRNQyLQKQLLEVKEEN 1888 4444444444220111.......11222222222220000222222222223344455555555555555544321444444555555 PP == domain 22 score: 19.6 bits; conditional E-value: 2.3e-07 PRKG1_interact 5 lyekalqenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENg 90 ye+a++en rLk ++e+l++ ++ +k++le +k k+e+ k++ + + + + +er i+ + +v+e+L+ eN++Lk g FUN_001422-T1 1894 EYEQARKENPRLKARVEDLQEYVEILKAELEASK-KREKARKKNLGTGMGGQSVEDMERVIAAMR---RVVERLQGENDQLKKSVG 1975 59*****************************987.688999999999****************98...6889999******98666 PP == domain 23 score: 3.4 bits; conditional E-value: 0.026 PRKG1_interact 6 yekalqenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgALiRVisk 98 y + +en+rLk++l+++k ++ + ++ + s+ +++ + + e+ + +l++e++ +e+Lka N L + L+R + + FUN_001422-T1 1981 YGEVIKENKRLKQELDKAKGASVKTGGQSSRGVN----ASA-NTTKLMAE-----NEKLLKNLKKEMEEVEKLKAANANLEQRKEDLVREMEQ 2063 6778899999999999998888777777666432....111.12222222.....34567789999999999999999999999888886655 PP == domain 24 score: -6.4 bits; conditional E-value: 4 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqe..........slskrssllelekrEkra......lerkiseleeelkvleeL 78 ene+L ++l++ +e++++k+ +++q++e + ++s + l+ +E ++ +e k+ le el++ ++L FUN_001422-T1 2025 ENEKLLKNLKKEMEEVEKLKAANANLEQRKEdlvremeqlqQKLTNSNMGTLDSKEWKSvvlpkiYEEKMRKLEAELEKKTNL 2107 55555555555555555555555555544444444444443333344455555555443222222577777777777666655 PP == domain 25 score: -4.9 bits; conditional E-value: 4 PRKG1_interact 14 erLkekleelkkelaeiksklekvkqkqeslskrsslle 52 ++L +le+ + l++ik+ l+ +++++ +l++++ le FUN_001422-T1 2095 RKLEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELE 2133 344444444444444444444444443333322222221 PP == domain 26 score: 0.4 bits; conditional E-value: 0.23 PRKG1_interact 6 yekalqenerLkekleelkkelaeiksklekvkqkqe 42 y k ++ +L+++l++++ e +++ +++ k++++ e FUN_001422-T1 2205 YDKMMTDDVELRTRLKTVELERDRLSHEITKLRKELE 2241 7788888999999999999999999999999875444 PP >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 23.2 0.016 1.1e+02 11 138 .. 14 148 .. 9 150 .. 0.80 2 ? -7.5 17.3 4 2.6e+04 51 114 .. 161 228 .. 122 252 .. 0.44 3 ? -3.6 18.3 2.3 1.5e+04 35 135 .. 259 355 .. 235 366 .. 0.65 4 ! 4.5 5.6 0.0074 47 47 90 .. 406 449 .. 398 468 .. 0.58 5 ! 16.6 5.1 1.3e-06 0.0085 55 107 .. 501 553 .. 471 557 .. 0.86 6 ? -3.9 4.4 2.9 1.9e+04 63 129 .. 581 650 .. 576 659 .. 0.69 7 ? -9.2 19.3 4 2.6e+04 13 117 .. 640 747 .. 627 774 .. 0.66 8 ? -3.8 9.1 2.7 1.7e+04 54 90 .. 795 831 .. 754 836 .. 0.58 9 ? 0.1 11.4 0.17 1.1e+03 58 112 .. 850 904 .. 843 931 .. 0.75 10 ? -0.5 21.3 0.26 1.7e+03 4 138 .. 931 1071 .. 928 1073 .. 0.86 11 ! 8.1 18.4 0.00058 3.7 4 127 .. 1083 1204 .. 1082 1215 .. 0.82 12 ? -10.0 11.9 4 2.6e+04 24 42 .. 1220 1238 .. 1206 1331 .. 0.43 13 ? -9.9 20.1 4 2.6e+04 78 139 .. 1328 1389 .. 1259 1390 .. 0.71 14 ? -4.5 16.0 4 2.6e+04 10 110 .. 1337 1441 .. 1328 1455 .. 0.62 15 ? -7.6 22.8 4 2.6e+04 45 125 .. 1454 1528 .. 1420 1539 .. 0.67 16 ? -5.3 13.2 4 2.6e+04 26 97 .. 1505 1581 .. 1492 1584 .. 0.71 17 ? -13.0 39.6 4 2.6e+04 9 140 .] 1535 1687 .. 1528 1687 .. 0.68 18 ? -10.8 27.5 4 2.6e+04 5 100 .. 1602 1700 .. 1599 1716 .. 0.70 19 ? -7.3 17.8 4 2.6e+04 13 117 .. 1732 1851 .. 1727 1866 .. 0.68 20 ! 12.7 12.5 2.2e-05 0.14 21 123 .. 1869 1973 .. 1861 1980 .. 0.91 21 ? -0.9 14.1 0.36 2.3e+03 75 124 .. 2019 2068 .. 1978 2080 .. 0.68 22 ? 0.2 12.6 0.16 1e+03 23 108 .. 2091 2175 .. 2088 2183 .. 0.83 23 ? 3.3 1.9 0.018 1.2e+02 8 37 .. 2215 2244 .. 2194 2283 .. 0.59 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.016 CENP-F_leu_zip 11 kLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnss 105 kL + ++ + d + L+ ++ee v e E+s +e++++ +e +l++ l+q l + +r+e++ L ++q+ + + + + + FUN_001422-T1 14 KLSKKNKELSEYLDEIRVLQEANDELEERIKDVQKELEESTEEMNKMTEECTKLKTILQQSDLIIDDMRKERDALRAQVQDLRMQFANKTDTDDD 108 56566666666678899999999999999999999999999999999999999999999999999999999999999999999888888888888 PP CENP-F_leu_zip 106 lenlleekEqe.......kvqmkeeskaaveeLqtqlkel 138 + +++ k +e k + e++k+ veeLq+q+ l FUN_001422-T1 109 IMVAVNAKVEEwkavlaaKEIELEQYKSLVEELQQQITGL 148 8888877766666778766677788899999999888776 PP == domain 2 score: -7.5 bits; conditional E-value: 4 CENP-F_leu_zip 51 kaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkk.......qervseLeslnsslenlleekE 114 +ev++ ++ie+l++el++ +++ + s e++ k+L +k q+r++eL+s+ +++le +E FUN_001422-T1 161 HQEVKEKDEKIEMLQKELEKAASEMHGVASYAEQV-KSLSEKgvpsayqQKRIKELNSTLQ--REQLESLE 228 23444444444444444444444444444444444.3333322222222445555544432..34455555 PP == domain 3 score: -3.6 bits; conditional E-value: 2.3 CENP-F_leu_zip 35 mseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeeskaave 129 e +++++ e ++ ka++ ++ie l+++ ++le++++ e+eeL + L+ ++ L+ + ++ ++ Eq + ++ + +++ve FUN_001422-T1 259 RGEYGLSEAVQEIKDCKAQIRIRDQNIEDLTSQINNLEIEVNDAEMENEELRERLGMDPKE--KLDIEDVRHKKKVKA-EQ-AIALNRALNKEVE 349 4455678999999********************************9*99999999866553..444444444444432.22.2333333333333 PP CENP-F_leu_zip 130 eLqtql 135 L+ ++ FUN_001422-T1 350 RLEEER 355 333333 PP == domain 4 score: 4.5 bits; conditional E-value: 0.0074 CENP-F_leu_zip 47 aEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLq 90 +E ka + l+ e+e+ +++ ++++++++++ se++eL+ e + FUN_001422-T1 406 SEVTKAVNKRLEGEVEKSEQQIEKFKTNMKKIESENKELKDENK 449 55555555556666666666666666666666666555543322 PP == domain 5 score: 16.6 bits; conditional E-value: 1.3e-06 CENP-F_leu_zip 55 etlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnssle 107 +lka+ie+l+ + ++l+++L + r+e + +++ k+ ++++Le+ l+ FUN_001422-T1 501 LQLKAQIEQLSGRNEELRHELHNAREETAKAVMQVERKNTKIEDLEKEVQVLK 553 469*******************************************9887766 PP == domain 6 score: -3.9 bits; conditional E-value: 2.9 CENP-F_leu_zip 63 elaeelrqleldLvtlrsekeeLtkeLqkkqervse.LeslnsslenlleekEqe..kvqmkeeskaave 129 l+e+l + ++L+ + +++k+L+ +++vs L + l+ekE+ +++ +e ka++e FUN_001422-T1 581 SLNEHLIHVLQELSLKEELLAKMEKDLELFKRKVSViLHQKGLLYADYLREKEKWdeERRASDEEKASME 650 5556666666666665566678888888888888853677777788889988864337777777777776 PP == domain 7 score: -9.2 bits; conditional E-value: 4 CENP-F_leu_zip 13 KeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnssle 107 ++s ++++s++ e + l + e+ ++ + + +++k+ ++++ ++ l+ + + l+ +++++ L ke +k ++ v +e++ s+ FUN_001422-T1 640 RASDEEKASMELSREHDKIRLLEFERLLDTLDKDEDKQKKRLSEMARKVTVLRVNEKSLSRRYTAMQEVETALRKENKKFRNDVVAMETAISERL 734 33333333333333333333445677778888899999999999999999999999999999999999999999999999999999999988877 PP CENP-F_leu_zip 108 nllee.kEqe..k 117 l++ kE+ k FUN_001422-T1 735 GYLQRhKEMStyK 747 7776426666441 PP == domain 8 score: -3.8 bits; conditional E-value: 2.7 CENP-F_leu_zip 54 vetlkaeieelaeelrqleldLvtlrsekeeLtkeLq 90 v +l+a ++ l+e+ +l+ ++++l++++ +L+++L+ FUN_001422-T1 795 VDSLEADKKLLEETEVELKKEMTALKERNHSLEQMLN 831 3445555555555555555555555555555555554 PP == domain 9 score: 0.1 bits; conditional E-value: 0.17 CENP-F_leu_zip 58 kaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenllee 112 ++ei++++++l le++ + r++ ++ t++ + q+ v++Le++ns+le+ e FUN_001422-T1 850 QEEIDRISRKLATLEMKELNERERADHATRKYDQLQSLVQQLEERNSELEHKFAE 904 6789999999999999999999999999999999999999999999999876543 PP == domain 10 score: -0.5 bits; conditional E-value: 0.26 CENP-F_leu_zip 4 kklhvlekLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrq......leldLvtlrsekeeLtkeLq 90 +l+v+ + + e++++ Lk v L+ e++ ++ e ++ + E++ +e+ +l++++ ++ e + l++ +v+l+ + ++L+ FUN_001422-T1 931 THLSVTRRVQSLEESESKLKVEVSRLKEVAEVASHQTEAIKAQQESQDKELTSLRKQLYDMQMENDDktiigkLHHHIVALQVSEGTAVRKLE 1023 5677888888999999******************************************999877543223333999******8888888**** PP CENP-F_leu_zip 91 kkqervseLeslnsslenlleekEqekvqmkeeskaaveeLqtqlkel 138 ++ s e+l le+ + ek q+ + k e+ ++ + L++ +++l FUN_001422-T1 1024 AATQKLSRQEALVLRLEQKIDEKDQALYHAKMEARNKAKFLKKTIQDL 1071 **************************8888878877778888777766 PP == domain 11 score: 8.1 bits; conditional E-value: 0.00058 CENP-F_leu_zip 4 kklhvlekLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqerv 96 k+ + +e ++ ++ L+ ++ + + e +e + +++l+ + ++ + tlk+ + ++ ++ ++++ +lr + +L++ + qe+ FUN_001422-T1 1083 KQEKFAETMRTLHDDKRTLERELKKAKNDREAAEDRLAELKLQHDGLQELMATLKDGKGA--AKVTEWHAKMGELRLQDLKLNRAVTRLQEEL 1173 566666666666667777777777777777777777777777777777777777777766..99***************************** PP CENP-F_leu_zip 97 seLeslnsslenlleekEqekvqmkeeskaa 127 + Le++ e+ ++++E+e+vqm +e++ + FUN_001422-T1 1174 KYLENVVKVHERSISDLEDENVQMAKEHEDR 1204 **************************99876 PP == domain 12 score: -10.0 bits; conditional E-value: 4 CENP-F_leu_zip 24 dkvenLerelemseenqek 42 dk e+ +rel ++ + e+ FUN_001422-T1 1220 DKLEKQQRELAEAATKFEE 1238 2222222222222222222 PP == domain 13 score: -9.9 bits; conditional E-value: 4 CENP-F_leu_zip 78 lrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeeskaaveeLqtqlkeln 139 l++e+ e ++ L+ q++vs+L+++ e+ l++ + ++ +ee+k+++e+ +++++ l+ FUN_001422-T1 1328 LTEENYETKRALKVAQATVSSLQQMLAHKEESLNKYQAMLKEAREEAKTQSEQHKVEIQLLQ 1389 55788888888888888888888888888888888888888888888888888777777665 PP == domain 14 score: -4.5 bits; conditional E-value: 4 CENP-F_leu_zip 10 ekLKeserkadsLkd....kvenLerelemseenqekvileaEnskaevetlkaeieelaee..lrqleldLvtlrsekeeLtkeLqkkqerv 96 LK ++ +sL++ k e+L++ m++e +e++++++E+ k e++ l++ ++ + e +r+ + + +++ + ++ k+ +r FUN_001422-T1 1337 RALKVAQATVSSLQQmlahKEESLNKYQAMLKEAREEAKTQSEQHKVEIQLLQDRLHLESDEtfRRKKTFHMDSVSADDSQV--PTHKQLSRL 1427 4555555555555542222668888888999999999999999999999998887654333311445555555666665555..445555667 PP CENP-F_leu_zip 97 seLeslnsslenll 110 seLe++ + n+l FUN_001422-T1 1428 SELEEMVAEQDNAL 1441 77777766666666 PP == domain 15 score: -7.6 bits; conditional E-value: 4 CENP-F_leu_zip 45 leaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeesk 125 +E++k+ e +++ +++++++ ++ + +L++++sek e ++ + ++ + ++ L+ ++ kE++++ + k FUN_001422-T1 1454 EVMETKKEHEEDVENFKQQMTRKDEEHSNELKKITSEKMERDERIMEQSKMIEVLKDELETA------KEAAERAPSKTLK 1528 33678888888899999999999999999999999999999888888888887666554444......3444444444445 PP == domain 16 score: -5.3 bits; conditional E-value: 4 CENP-F_leu_zip 26 venLerelemseenqekvile.....aEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervs 97 +e L+ ele+++e e++ ++ +E ++++ +++ + l++ l ql++d+v++ +e+ + + ++q+ v+ FUN_001422-T1 1505 IEVLKDELETAKEAAERAPSKtlkhlVERLRNQLALKEKQQKSLSQALLQLRADMVSTAEENVQAHARRAEEQANVQ 1581 78888888888888887654411111344444444456677789999999999999999999988888888887775 PP == domain 17 score: -13.0 bits; conditional E-value: 4 CENP-F_leu_zip 9 lekLKeserkadsLkdkvenLerelems.eenqekvileaEnskaevet........lkaeieelaeelrqleldLvtlr.......sekeeL 85 +++L e+++ sL + ++L +++ een + aE++ a v+ l++ ieel+e++++++ +L + r ek++L FUN_001422-T1 1535 RNQLALKEKQQKSLSQALLQLRADMVSTaEENVQAHARRAEEQ-ANVQHvvdkettgLQSRIEELQERMEKFKKELRKQRdketallGEKDKL 1626 5566666777778888888888887544044433333344433.33333333455559******************999988888889***** PP CENP-F_leu_zip 86 tkeLqkkqerv....seLeslnsslenlleekEqe...kvqmkeeskaaveeLqtqlkelne 140 +++L kk + eL++l+ +++++le+k qe +++ + + +++e L+ + k l+e FUN_001422-T1 1627 KQDLSKKDAALlkfgRELKELE-TVQEQLEKKDQElriEKNKHAQERSEIENLREKVKSLQE 1687 *******987733333455443.455667777777755555555667789999999998887 PP == domain 18 score: -10.8 bits; conditional E-value: 4 CENP-F_leu_zip 5 klhvlekLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieela...eelrqleldLvtlrsekeeLtkeLqkkqe 94 + +++L++ + k+ L + ++L+++l ++ + k +e ++ e+l+++ +el+ ++ q ++++++lr+ ++L+++L+++++ FUN_001422-T1 1602 MEKFKKELRKQRDKETALLGEKDKLKQDLSKKDAALLKFGRELKELETVQEQLEKKDQELRiekNKHAQERSEIENLREKVKSLQEKLKQERK 1694 556778888888888888888899999998887777777776666666666666666666511133345566777777777788888888877 PP CENP-F_leu_zip 95 rvseLe 100 + +L+ FUN_001422-T1 1695 KSADLD 1700 777776 PP == domain 19 score: -7.3 bits; conditional E-value: 4 CENP-F_leu_zip 13 KeserkadsLkdkvenLerelemseenqe...kvileaEnskaevet..........lkaeieelaeelrqleldLvtlrsekeeLtke.Lqk 91 K+ ++k + Lk+k + rele +++++ ++ aE+ ka + + ++ + +e ++l++ + +l +e++eL +e + FUN_001422-T1 1732 KKWQQKVETLKGKLAEKTRELEKAQKSNAmlrEALNRAEKDKAGLHSrlkssvkagvVEPSV-VTNEVVQDLKHSIFKLEEENQELRREkVLG 1823 77788888899999888999988888764111556678888888877755553333222222.235557888888888889999997753556 PP CENP-F_leu_zip 92 kqervseLeslnsslenlleekEqe..k 117 + ++++ Le +n + + + ++E + + FUN_001422-T1 1824 HDKQMEALELRNRQQMEYIGRLERDlaE 1851 6778999999999999999888888533 PP == domain 20 score: 12.7 bits; conditional E-value: 2.2e-05 CENP-F_leu_zip 21 sLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkq..ervseLeslnsslenlle 111 L+++ + L+++l +++e++ ++ e E++++e lka +e l+e + l+++L++ +++ + +k+L++ + v+++e++ +++++e FUN_001422-T1 1869 ELHQRNQYLQKQLLEVKEENMELRFEYEQARKENPRLKARVEDLQEYVEILKAELEASKKREKARKKNLGTGMggQSVEDMERVIAAMRRVVE 1961 58999999***************************************************999999999987542278**************** PP CENP-F_leu_zip 112 ekEqekvqmkee 123 ++ e+ q+k++ FUN_001422-T1 1962 RLQGENDQLKKS 1973 *99999888876 PP == domain 21 score: -0.9 bits; conditional E-value: 0.36 CENP-F_leu_zip 75 LvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkees 124 ++l e+e+L k+L+k+ e+v+ L+++n le+ e++ e+ q++++ FUN_001422-T1 2019 TTKLMAENEKLLKNLKKEMEEVEKLKAANANLEQRKEDLVREMEQLQQKL 2068 44566788888888888888888888888877765554444444444433 PP == domain 22 score: 0.2 bits; conditional E-value: 0.16 CENP-F_leu_zip 23 kdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslen 108 ++k +Le+ele + + +++ + + + +l ++ +el+e+ le ++++s+ + L ke q+ + rv +Les ++++ + FUN_001422-T1 2091 EEKMRKLEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELEEKVAILERFPTNIKSDSD-LVKEFQQTRLRVATLESEKEEILH 2175 5788899999999888888888888888777788999999999999999999999999976.6699***********999887655 PP == domain 23 score: 3.3 bits; conditional E-value: 0.018 CENP-F_leu_zip 8 vlekLKeserkadsLkdkvenLerelemse 37 ++ +LK +e + d L + +L +ele + FUN_001422-T1 2215 LRTRLKTVELERDRLSHEITKLRKELEAFD 2244 344555555555666655655555555443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2289 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4862 (0.190331); expected 510.9 (0.02) Passed bias filter: 813 (0.0318262); expected 510.9 (0.02) Passed Vit filter: 365 (0.0142885); expected 25.5 (0.001) Passed Fwd filter: 166 (0.00649834); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 3.88u 0.49s 00:00:04.37 Elapsed: 00:00:00.71 # Mc/sec: 13078.71 // Query: FUN_001422-T2 [L=229] Description: FUN_001422 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.022 15.1 6.1 0.022 15.1 6.1 2.9 4 CENP-H Centromere protein H (CENP-H) 0.035 14.7 10.1 0.035 14.7 10.1 2.6 3 ADIP Afadin- and alpha -actinin-Binding 0.078 13.9 16.7 0.2 12.6 16.6 1.9 1 Fez1 Fez1 0.17 11.5 9.3 0.039 13.6 4.7 2.1 2 FH2 Formin Homology 2 Domain 2 8.9 21.4 10 6.6 20.4 2.4 2 UPF0242 Uncharacterised protein family (UPF0242) N-te 2.1 8.3 10.5 2.3 8.1 9.6 1.4 1 Exonuc_VII_L Exonuclease VII, large subunit 2.1 8.8 7.0 2.2 8.8 0.7 2.3 2 UPF0240 Uncharacterised protein family (UPF0240) 2.6 7.8 21.0 0.47 10.2 14.7 2.2 2 LIP-1 Liprin-alpha-like coiled coil domain 2 5.8 7.6 21.3 1 10.0 14.4 3.0 3 BRE1 BRE1 E3 ubiquitin ligase 5.9 7.9 13.7 0.45 11.5 6.6 2.7 3 DUF4164 Domain of unknown function (DUF4164) 6.1 7.4 8.0 2 8.9 0.5 3.2 3 Bcr-Abl_Oligo Bcr-Abl oncoprotein oligomerisation domain 6.6 7.6 12.6 4 8.3 1.2 2.8 3 DUF3496 Domain of unknown function (DUF3496) 9.4 6.0 20.8 3.9 7.3 15.0 2.7 3 GAS Growth-arrest specific micro-tubule binding Domain annotation for each model (and alignments): >> CENP-H Centromere protein H (CENP-H) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 1 2e+03 8 28 .. 25 43 .. 12 66 .. 0.50 2 ? 2.6 0.2 0.074 1.5e+02 128 168 .. 60 102 .. 46 103 .. 0.71 3 ? 15.1 6.1 1.1e-05 0.022 96 170 .. 113 185 .. 109 191 .. 0.90 4 ? -2.6 0.1 2.9 5.7e+03 101 114 .. 199 212 .. 192 219 .. 0.46 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1 CENP-H 8 dqlqeleleialleaqeeeel 28 + + el le+al++ +++e + FUN_001422-T2 25 ENMYEL-LEMALVSPDSKE-A 43 344444.666666655543.2 PP == domain 2 score: 2.6 bits; conditional E-value: 0.074 CENP-H 128 elaaellelakeqkskk..eeiddpelkeqlekleaelkksrq 168 ++++l++ + ++ ++ +++++el ++++ le el+++++ FUN_001422-T2 60 MKVKSLQAELAADEMHQggGGEREQELVDEIAHLEGELQRYQK 102 4555555555545555556788888899999999999999875 PP == domain 3 score: 15.1 bits; conditional E-value: 1.1e-05 CENP-H 96 sailklsqelreleeeLtevekerlrlkrknrelaaellelakeqkskkeeiddpelkeqlekleaelkksrqrw 170 +i +++++ ++le+eL+e e+ + k+kn +la++l + ++e+ks k+++d+++ l l+++++++r+ + FUN_001422-T2 113 REIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGK--LDLRDLQRQFEQQRESM 185 68999*************************************************99..67888888888888765 PP == domain 4 score: -2.6 bits; conditional E-value: 2.9 CENP-H 101 lsqelreleeeLte 114 ls++ +el+e L+e FUN_001422-T2 199 LSKKNKELSEYLDE 212 33333333333333 PP >> ADIP Afadin- and alpha -actinin-Binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.1 0.25 4.9e+02 67 111 .. 54 98 .. 10 103 .. 0.58 2 ? 14.7 10.1 1.8e-05 0.035 67 133 .. 114 180 .. 110 188 .. 0.93 3 ? -1.5 0.0 1.8 3.5e+03 43 65 .. 185 207 .. 183 218 .. 0.68 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.25 ADIP 67 eierlqseierlkeqledlerelalleakerqlekklktleqklk 111 e + ++++l+++l++ e+ + ++e++l ++++le l+ FUN_001422-T2 54 EVTKAVMKVKSLQAELAADEMHQGGGGEREQELVDEIAHLEGELQ 98 444445556666666666666666666666666666666665554 PP == domain 2 score: 14.7 bits; conditional E-value: 1.8e-05 ADIP 67 eierlqseierlkeqledlerelalleakerqlekklktleqklknekeelqrlknalqqiktqfah 133 ei + +++ + l+++l ++e + ++k ql +l ++e+ +k++k++l r k +l +++ qf++ FUN_001422-T2 114 EIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQ 180 7889999999**************************************************9999986 PP == domain 3 score: -1.5 bits; conditional E-value: 1.8 ADIP 43 Llqqrerdlefreslnetirkle 65 ++ +r d ef+ +l++++++l+ FUN_001422-T2 185 MVIRRGGDSEFKDKLSKKNKELS 207 55566667777777777777665 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 16.6 0.0001 0.2 32 180 .. 54 206 .. 32 219 .. 0.73 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.0001 Fez1 32 eivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqea 127 e+ + +++ l+a+l++ e + e+ ++ e+ +e+eLqr ++ + e+ + +++++ r++l++ +e++e+ ++++ ++q +++ FUN_001422-T2 54 EVTKAVMKVKSLQAELAADEMHQGGGGEREQELVDEIAHLEGELQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANR 149 666666789999***********************************7766666666555555566666655554444444443333333332222 PP Fez1 128 ....eealeslkreverlkaeLkeerqrkeeqaksFeeERrtWqeeKekVirYqkQL 180 e++ +slkr+++r k L+ +++ e+q++s R +e K+k + k L FUN_001422-T2 150 ldaaERENKSLKRDLDRGKLDLRDLQRQFEQQRESMVIRRGGDSEFKDKLSKKNKEL 206 3334788999**********************9999999988888888887777776 PP >> FH2 Formin Homology 2 Domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 0.3 5.9e+02 272 328 .. 8 63 .. 2 76 .. 0.61 2 ? 13.6 4.7 2e-05 0.039 258 355 .. 88 185 .. 82 222 .. 0.94 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.3 FH2 272 kaakvnleelekevkklekglkklekelessekkeepsdkfvevlkeflkeaeeklk 328 k+ n+e+l++++++ e + le l s ++ke + ++ +l e++ +a k+k FUN_001422-T2 8 KVMGANIEALREDLDAAENMYELLEMALVSPDSKEAVDANMMIQLFEVT-KAVMKVK 63 5556677888888888888888777777777764444444444444432.3334444 PP == domain 2 score: 13.6 bits; conditional E-value: 2e-05 FH2 258 pelldfsseLsnvkkaakvnleelekevkklekglkklekelessekkeepsdkfvevlkeflkeaeeklkkleeelkeakelfkelveYfgedpk 353 +e+ +++ eL+ +k + e++ e++++e + +le+el+++e+++ ++++ +++l l+ ae++ k+l+ +l++ k + +l + f ++++ FUN_001422-T2 88 DEIAHLEGELQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQRE 183 78999**************************************************************************99999999999988776 PP FH2 354 ev 355 + FUN_001422-T2 184 SM 185 65 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 20.4 0.0052 10 91 182 .. 114 201 .. 61 211 .. 0.80 2 ? -0.6 0.1 0.86 1.7e+03 140 160 .. 194 214 .. 190 220 .. 0.64 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0052 UPF0242 91 eleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfaefkleseeqlkekqlllneyqetieeqrsvlekrqdqieeLeskvrD 182 e+++ ++ + le+el++kee+ + k++++ql +l++++++++ +k++ l + +l l +q ++e+qr+++ r +e k FUN_001422-T2 114 EIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRD----LDRGKLDLRDLQRQFEQQRESMVIRRGGDSEFKDKLSK 201 55666666789****************************99999888776....6689999**************98877666666655555 PP == domain 2 score: -0.6 bits; conditional E-value: 0.86 UPF0242 140 eseeqlkekqlllneyqetie 160 e +++l +k++ l+ey ++i FUN_001422-T2 194 EFKDKLSKKNKELSEYLDEIR 214 456666666666666666665 PP >> Exonuc_VII_L Exonuclease VII, large subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 9.6 0.0012 2.3 146 264 .. 97 211 .. 81 220 .. 0.67 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0012 Exonuc_VII_L 146 lerleelekrleralkrrlerkrqrlerlarrlksperlleqqrqrldeleerleralkrkleekrerleelearleraspeerleeakerlealk 241 l+r ++++ + + r++++ +++ ++l+r+l++ e+ + q++++ d+l++rl++ ++r+ ++ +++l++ + l ++ ++++e+++e++ + FUN_001422-T2 97 LQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDA-AERENKSLKRDLDRGKLDL--RDLQRQFEQQRESMVIR- 188 33333333344455557788888899999999999999999999999**9999999.6667677777777777444..56677777777666443. PP Exonuc_VII_L 242 erlkralkrklekkkerlealaa 264 + ++++k+kl+kk+++l++ + FUN_001422-T2 189 RGGDSEFKDKLSKKNKELSEYLD 211 55666777777777777766554 PP >> UPF0240 Uncharacterised protein family (UPF0240) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.7 0.054 1.1e+02 39 68 .. 121 150 .. 117 154 .. 0.89 2 ? 8.8 0.7 0.0011 2.2 48 77 .. 190 219 .. 166 223 .. 0.78 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.054 UPF0240 39 tekdleevleenpeikeelkkkdeqLlsrL 68 +++ le+ l+e++e + k+k++qL +rL FUN_001422-T2 121 SRNALERELNEKEEAFFQEKNKNDQLANRL 150 677899999*****999**********998 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0011 UPF0240 48 eenpeikeelkkkdeqLlsrLkdvyVeSkd 77 + e+k++l+kk+++L ++L +++V+ ++ FUN_001422-T2 190 GGDSEFKDKLSKKNKELSEYLDEIRVNHHQ 219 44667*********************9886 PP >> LIP-1 Liprin-alpha-like coiled coil domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.4 0.1 2e+02 8 188 .. 65 102 .. 12 113 .. 0.64 2 ? 10.2 14.7 0.00024 0.47 87 183 .. 113 213 .. 108 220 .. 0.85 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.1 LIP-1 8 lqealekqkaelsqakervaelsarvaeleeelsaaqkellkaqeanaklqrdlrealaqkedqeerittlEkRylnaqREatslhdlndkLEqel 103 lq++l FUN_001422-T2 65 LQAEL------------------------------------------------------------------------------------------- 69 33333........................................................................................... PP LIP-1 104 ankeaalrlsEekvrqlqerlelaeqklaqslkkaeslpeveaelaqrveALskaeerhgsaeerlrrlesqleeknaelerarq 188 + e ++g er ++l +++ + el+r ++ FUN_001422-T2 70 ----------------------------------------------------AADEMHQGGGGEREQELVDEIAHLEGELQRYQK 102 ....................................................333344445555555555555555555555554 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00024 LIP-1 87 REatslhdlndkLEqelankeaalrlsEekvrqlqerlelaeqk...laqslkkae.slpeveaelaqrveALskaeerhgsaeerlrrlesqlee 178 RE ++++ + LE+el++ke a+ ++ +k++ql +rl++ae++ l++ l + + l +++ + +q+ e + + +++++l++ +++l+e FUN_001422-T2 113 REIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAEREnksLKRDLDRGKlDLRDLQRQFEQQRESMVIRRGGDSEFKDKLSKKNKELSE 208 999999***********************************9652227777777664699999999999999888888888899999999999999 PP LIP-1 179 knael 183 e+ FUN_001422-T2 209 YLDEI 213 88776 PP >> BRE1 BRE1 E3 ubiquitin ligase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.3 0.58 1.1e+03 13 13 .. 77 77 .. 40 101 .. 0.51 2 ? 10.0 14.4 0.00053 1 3 94 .. 113 204 .. 111 205 .. 0.91 3 ? 0.1 0.1 0.61 1.2e+03 66 80 .. 198 212 .. 191 221 .. 0.66 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.58 BRE1 13 e 13 FUN_001422-T2 77 G 77 1 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00053 BRE1 3 kELvklekafeelqeqlskkvkeltaleekklrleaekakadqkyfaamrskdalenelkkLnkllsKsselieqlkelekelvrklkelek 94 E+ ++e+ +++l+ +l++k + + ++k +l + + a+++ ++++r+ d + +l+ L+++ ++++e++ ++e++ kl++ +k FUN_001422-T2 113 REIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQRESMVIRRGGDSEFKDKLSKKNK 204 79*********************************************************************987766677777777766655 PP == domain 3 score: 0.1 bits; conditional E-value: 0.61 BRE1 66 kllsKsselieqlke 80 kl +K++el+e l e FUN_001422-T2 198 KLSKKNKELSEYLDE 212 456677777777766 PP >> DUF4164 Domain of unknown function (DUF4164) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 3.4 6.6e+03 49 61 .. 15 27 .. 8 35 .. 0.57 2 ? 11.5 6.6 0.00023 0.45 10 82 .. 83 156 .. 78 163 .. 0.91 3 ? 3.4 2.1 0.077 1.5e+02 30 60 .. 139 169 .. 134 185 .. 0.68 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 3.4 DUF4164 49 srLaqeLdqaear 61 + L ++Ld+ae+ FUN_001422-T2 15 EALREDLDAAENM 27 4456666666655 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00023 DUF4164 10 lkrLeaaldrLesavdrrleaerae.aeleaeveaLqadrsrLaqeLdqaearaneleeanrEisrrLdsaiet 82 +++L + +Le ++r + +++ +++ +e++++++ r+ L+ eL ++e + ++ n+ ++rLd+a + FUN_001422-T2 83 EQELVDEIAHLEGELQRYQKYDGMGgEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERE 156 6888889999************998789******************************************9765 PP == domain 3 score: 3.4 bits; conditional E-value: 0.077 DUF4164 30 aeraeaeleaeveaLqadrsrLaqeLdqaea 60 +++++++l++++ a +++ + L +Ld + FUN_001422-T2 139 EKNKNDQLANRLDAAERENKSLKRDLDRGKL 169 5566667777777777777777777776555 PP >> Bcr-Abl_Oligo Bcr-Abl oncoprotein oligomerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 1.4 2.8e+03 35 49 .. 57 71 .. 46 75 .. 0.61 2 ? 1.0 0.4 0.3 5.9e+02 27 50 .. 109 132 .. 100 141 .. 0.83 3 ? 8.9 0.5 0.001 2 27 54 .. 158 185 .. 149 189 .. 0.87 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1.4 Bcr-Abl_Oligo 35 rCkaslrrLekelne 49 + +++ L+ el+ FUN_001422-T2 57 KAVMKVKSLQAELAA 71 444455666666554 PP == domain 2 score: 1.0 bits; conditional E-value: 0.3 Bcr-Abl_Oligo 27 edieqeLerCkaslrrLekelnee 50 ed +e+ + +s +Le+elne FUN_001422-T2 109 EDFMREIRQIENSRNALERELNEK 132 577788999999999999999974 PP == domain 3 score: 8.9 bits; conditional E-value: 0.001 Bcr-Abl_Oligo 27 edieqeLerCkaslrrLekelneekfkv 54 + ++++L+r k +lr L+++ ++ + + FUN_001422-T2 158 KSLKRDLDRGKLDLRDLQRQFEQQRESM 185 56899****************9988766 PP >> DUF3496 Domain of unknown function (DUF3496) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 3.1 6.2e+03 15 26 .. 59 70 .. 47 76 .. 0.61 2 ? 6.0 2.9 0.011 22 12 56 .. 112 155 .. 108 161 .. 0.87 3 ? 8.3 1.2 0.0021 4 5 75 .. 154 223 .. 152 227 .. 0.91 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 3.1 DUF3496 15 lskmktsqedsn 26 + k+k+ q + FUN_001422-T2 59 VMKVKSLQAELA 70 556666555554 PP == domain 2 score: 6.0 bits; conditional E-value: 0.011 DUF3496 12 eselskmktsqedsnkaeLEkYkqlyleelkvrksLsnkLnktne 56 e+ ++ +s++ + eL++ ++++++e + + L+n+L+ +++ FUN_001422-T2 112 MREIRQIENSRNAL-ERELNEKEEAFFQEKNKNDQLANRLDAAER 155 56889999999888.9************************98765 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0021 DUF3496 5 ElrikdLeselskmktsqedsnkaeLEkYkqlyleelkvrksLsnkLnktnerLaevstkllvekqqnrsl 75 E + k+L+ +l + k +d + + E+ ++ + + ++kL+k+n+ L+e ++ v+++q ++ FUN_001422-T2 154 ERENKSLKRDLDRGKLDLRDL-QRQFEQQRESMVIRRGGDSEFKDKLSKKNKELSEYLDEIRVNHHQFNFC 223 6788999999999999999*9.99***************************************99997765 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.2 0.71 1.4e+03 59 79 .. 17 37 .. 9 77 .. 0.52 2 ? 7.3 15.0 0.002 3.9 9 99 .. 96 186 .. 88 214 .. 0.77 3 ? 1.8 0.2 0.098 1.9e+02 155 177 .. 196 218 .. 192 222 .. 0.69 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.71 GAS 59 lkepLekaeeeveeLkkqlee 79 l+e L +ae+ e L+ l FUN_001422-T2 17 LREDLDAAENMYELLEMALVS 37 334444444333333333333 PP == domain 2 score: 7.3 bits; conditional E-value: 0.002 GAS 9 afeeiknYYnditrnnLelikslKeeiaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknlkarlkelek 99 +++ +++Y ++ + i++ ++ ++l+++ +e+e + + +++n +l+ L +ae+e++ Lk++l++ + d +l++ ++ +e+ FUN_001422-T2 96 ELQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQRESMV 186 5677777777777888999**************************************************9988888888877666665544 PP == domain 3 score: 1.8 bits; conditional E-value: 0.098 GAS 155 seelEkkeaqLeevlaaanldpe 177 +++l kk+++L+e+l + ++++ FUN_001422-T2 196 KDKLSKKNKELSEYLDEIRVNHH 218 56777778888887777766654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (229 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2143 (0.0838912); expected 510.9 (0.02) Passed bias filter: 698 (0.0273243); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.40 # Mc/sec: 2300.54 // Query: FUN_001422-T3 [L=2473] Description: FUN_001422 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-45 152.3 18.6 9.9e-45 152.3 18.6 19.2 20 CEP209_CC5 Coiled-coil region of centrosome protein CE29 0.0016 19.5 5.0 0.0016 19.5 5.0 26.6 25 PRKG1_interact cGMP-dependent protein kinase interacting dom 0.0054 17.4 22.1 0.0054 17.4 22.1 23.6 25 DUF7801 Domain of unknown function (DUF7801) 0.0092 16.5 5.1 0.0092 16.5 5.1 23.9 24 CENP-F_leu_zip Leucine-rich repeats of kinetochore protein C Domain annotation for each model (and alignments): >> CEP209_CC5 Coiled-coil region of centrosome protein CE290 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 8.0 1.1 7.2e+03 72 115 .. 201 248 .. 193 260 .. 0.80 2 ? -3.9 3.4 3.1 2e+04 74 104 .. 331 361 .. 256 384 .. 0.60 3 ? -6.2 9.6 4 2.6e+04 21 112 .. 408 490 .. 380 503 .. 0.48 4 ? -3.1 3.1 1.7 1.1e+04 69 125 .. 508 559 .. 491 561 .. 0.58 5 ? -11.8 14.8 4 2.6e+04 49 49 .. 648 648 .. 599 743 .. 0.52 6 ? -1.0 14.5 0.38 2.5e+03 8 106 .. 815 915 .. 810 932 .. 0.81 7 ? -2.8 0.0 1.4 9.2e+03 28 49 .. 943 964 .. 923 970 .. 0.80 8 ? -8.0 13.9 4 2.6e+04 5 118 .. 982 1099 .. 977 1109 .. 0.69 9 ? -4.5 8.9 4 2.6e+04 12 110 .. 1099 1197 .. 1091 1214 .. 0.74 10 ! 152.3 18.6 1.5e-48 9.9e-45 1 128 [] 1274 1401 .. 1274 1401 .. 1.00 11 ! 4.2 1.5 0.0095 61 73 113 .. 1448 1488 .. 1435 1500 .. 0.62 12 ? -3.2 2.4 1.9 1.2e+04 88 125 .. 1534 1568 .. 1507 1588 .. 0.52 13 ? -10.3 11.4 4 2.6e+04 14 58 .. 1666 1704 .. 1649 1770 .. 0.39 14 ? -13.2 16.1 4 2.6e+04 49 122 .. 1771 1843 .. 1731 1856 .. 0.58 15 ? -5.2 7.7 4 2.6e+04 56 96 .. 1915 1955 .. 1857 1964 .. 0.66 16 ? -2.2 3.6 0.94 6e+03 5 45 .. 1986 2027 .. 1982 2042 .. 0.77 17 ? -5.2 5.3 4 2.6e+04 5 59 .. 2061 2115 .. 2058 2122 .. 0.72 18 ? -12.1 15.6 4 2.6e+04 11 99 .. 2219 2312 .. 2204 2331 .. 0.46 19 ? -8.5 9.9 4 2.6e+04 4 90 .. 2280 2367 .. 2277 2410 .. 0.59 20 ? -3.6 2.1 2.5 1.6e+04 28 84 .. 2368 2424 .. 2335 2461 .. 0.58 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.1 CEP209_CC5 72 kknRelvkqkeeikylknlveeqertiss....leeeivqqnklqeer 115 kkn+el++ +ei+ l++ ++e e i++ lee ++nk+ ee+ FUN_001422-T3 201 KKNKELSEYLDEIRVLQEANDELEERIKDvqkeLEESTEEMNKMTEEC 248 89999****************999999752222677777788888875 PP == domain 2 score: -3.9 bits; conditional E-value: 3.1 CEP209_CC5 74 nRelvkqkeeikylknlveeqertissleee 104 + +l++ k ++ l++ v+e++ i+ l +e FUN_001422-T3 331 GLQLDADKGSLAMLHQEVKEKDEKIEMLQKE 361 3344455555555555555555555555544 PP == domain 3 score: -6.2 bits; conditional E-value: 4 CEP209_CC5 21 eerrraedraqele....lklkgLeeLlst.lkDakGaqkvteWhkkleeirlqelkknRelvkqkeeikylknlveeqertissleeeivqqnkl 111 e+ ++ dr+ e lk k L++Lls ++ ++G ++e + +++ + q ++++++ +i+ l+ v++ e+ FUN_001422-T3 408 LESLEVKDRMIMAEeaaaLKDKQLNDLLSRmMQYERGEYGLSEAVQEIKDCKAQIRIRDQNIEDLTSQINNLEIEVNDAEME-------------- 489 2222222222111111115555555555431344555555555555555555554444455555555555554444444443.............. PP CEP209_CC5 112 q 112 + FUN_001422-T3 490 N 490 3 PP == domain 4 score: -3.1 bits; conditional E-value: 1.7 CEP209_CC5 69 qelkknRelvkqkeeikylknlveeqertissleeeivqqnklqeerqlawdqreve 125 ++++++++++ i+ + l+ + ++ leee +q+++ ++ l r ve FUN_001422-T3 508 EDVRHKKKVKAE-QAIALNRALN----KEVERLEEERLQLKRQLRKQALHRGARAVE 559 444444444332.2233333333....335557777777777766666666666666 PP == domain 5 score: -11.8 bits; conditional E-value: 4 CEP209_CC5 49 D 49 + FUN_001422-T3 648 E 648 1 PP == domain 6 score: -1.0 bits; conditional E-value: 0.38 CEP209_CC5 8 dkakiqeeakkveeerrraedraqelelklkgLeeLlstl.kD.akGaqkvteWhkkleeirlqelkknRelvkqkeeikylknlveeqertissl 101 +k k ee++ +ee+ +e + ++l e Ll tl kD k ++++e +k+ +r+ e ++R ++++e l++ +++ + + FUN_001422-T3 815 EKEKWDEERRASDEEKASMELSREHDKIRLLEFERLLDTLdKDeDKQKKRLSEMARKVTVLRVNEKSLSRRYTAMQEVETALRKENKKFRNDVVAM 910 5677788888888888888888888889999*********54424777889*************************99999988888887777777 PP CEP209_CC5 102 eeeiv 106 e i FUN_001422-T3 911 ETAIS 915 76664 PP == domain 7 score: -2.8 bits; conditional E-value: 1.4 CEP209_CC5 28 draqelelklkgLeeLlstlkD 49 +a+ele k +eL + +D FUN_001422-T3 943 VQASELEAANKQYNELTAKYRD 964 4789999999999999988877 PP == domain 8 score: -8.0 bits; conditional E-value: 4 CEP209_CC5 5 LqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGa.......qkvteWhkkleeirlqelkknRelvkqkeeikylknlv 91 L+ dk+ ++e ++++e + +r + le + L++Lls + Ga +++ +kl ++ ++el + ++ + l+ lv FUN_001422-T3 982 LEADKKLLEETEVELKKEMTALKERNHSLE---QMLNDLLSKDGGQGGAdtssvrqEEIDRISRKLATLEMKELNERERADHATRKYDQLQSLV 1072 555666666666666666666666666666...445555554444444422221213466678999999*****999999999999999***** PP CEP209_CC5 92 eeqertissleeeivqqnklqeerqla 118 ++ e s+le + ++l+ e q + FUN_001422-T3 1073 QQLEERNSELEHKFAEISNLNLESQRI 1099 **************9999998777744 PP == domain 9 score: -4.5 bits; conditional E-value: 4 CEP209_CC5 12 iqeeakkveeerrraedraqelelklkgLeeLlstlk.DakGaqkvteWh.kkleeirlqelkknRelvkqkeeikylknlveeqertisslee 103 i++e ++ ++ e + + ++++Lee s lk ++ ++v e ++ e i+ q+ +++el+ + ++ y ++ ++ ++i +l FUN_001422-T3 1099 IERELREELSNSVTQETH-LSVTRRVQSLEESESKLKvEVSRLKEVAEVAsHQTEAIKAQQESQDKELTSLRKQL-YDMQMENDDKTIIGKLHH 1190 444444443333333333.34556899999999999944566788999762578999**************9986.999999999999****** PP CEP209_CC5 104 eivqqnk 110 iv ++ FUN_001422-T3 1191 HIVALQV 1197 **98764 PP == domain 10 score: 152.3 bits; conditional E-value: 1.5e-48 CEP209_CC5 1 tmlkLqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGaqkvteWhkkleeirlqelkknRelvkqkeeikylknlveeq 94 tm +L++dk+ +++e kk++++r+ aedr+ el l++ gL+eL++tlkD+kGa+kvteWh k+ e+rlq+lk+nR +++ +ee+kyl+n+v+ + FUN_001422-T3 1274 TMRTLHDDKRTLERELKKAKNDREAAEDRLAELKLQHDGLQELMATLKDGKGAAKVTEWHAKMGELRLQDLKLNRAVTRLQEELKYLENVVKVH 1367 89******************************************************************************************** PP CEP209_CC5 95 ertissleeeivqqnklqeerqlawdqreveleR 128 er is+le+e vq+ k +e+rql+w+qreveleR FUN_001422-T3 1368 ERSISDLEDENVQMAKEHEDRQLIWEQREVELER 1401 *********************************9 PP == domain 11 score: 4.2 bits; conditional E-value: 0.0095 CEP209_CC5 73 knRelvkqkeeikylknlveeqertissleeeivqqnklqe 113 + R++v +ee+k lk+ +e + + ++ ee + q+ kl + FUN_001422-T3 1448 HIRTIVGTREENKQLKKKHNELDLAFKQSEERLTQKDKLIN 1488 23666666666666666666666666666666666666555 PP == domain 12 score: -3.2 bits; conditional E-value: 1.9 CEP209_CC5 88 knlveeqertissleeeivqqnklqeerqlawdqreve 125 +++ +++e ++++ +++ +ee + + +q +ve FUN_001422-T3 1534 QQMLAHKEESLNKYQAM---LKEAREEAKTQSEQHKVE 1568 44444444443333321...222233333333333333 PP == domain 13 score: -10.3 bits; conditional E-value: 4 CEP209_CC5 14 eeakkveeerrraedraqelelklkgLeeLlstlkDakGaqk.vte 58 +e kk++ e+ + ++r++e ++ lkD+ ++k e FUN_001422-T3 1666 NELKKITSEKMERDERIME-------QSKMIEVLKDELETAKeAAE 1704 3334444444444444444.......44444444444322220222 PP == domain 14 score: -13.2 bits; conditional E-value: 4 CEP209_CC5 49 DakGaq.kvteWhkkleeirlqelkknRelvkq.keeikylknlveeqertissleeeivqqnklqeerqlawdqr 122 ++ G q ++ e ++++e+ + +el+k+R+ ++ e lk+ ++++ ++ ++ e+ +++++qe ql+ +++ FUN_001422-T3 1771 ETTGLQsRIEELQERMEKFK-KELRKQRDKETAlLGEKDKLKQDLSKKDAALLKFGRELKELETVQE--QLEKKDQ 1843 33343326777888888887.7888888654331344444555556677777777777777777765..4444444 PP == domain 15 score: -5.2 bits; conditional E-value: 4 CEP209_CC5 56 vteWhkkleeirlqelkknRelvkqkeeikylknlveeqer 96 W++k+e+++ + k+Rel+k + ++ l++ + e+ FUN_001422-T3 1915 NKKWQQKVETLKGKLAEKTRELEKAQKSNAMLREALNRAEK 1955 46799999999999999999999988888888877776665 PP == domain 16 score: -2.2 bits; conditional E-value: 0.94 CEP209_CC5 5 Lqedkakiqeeakkveeerrraedraqe.lelklkgLeeLls 45 L+ k++ee +++++e+ d+ +e lel+ + e + FUN_001422-T3 1986 LKHSIFKLEEENQELRREKVLGHDKQMEaLELRNRQQMEYIG 2027 666777899999999999999888877768999887666655 PP == domain 17 score: -5.2 bits; conditional E-value: 4 CEP209_CC5 5 LqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGaqkvteW 59 Lq++ ++++ee +++ e ++a + l +++ L+e + lk + a k e FUN_001422-T3 2061 LQKQLLEVKEENMELRFEYEQARKENPRLKARVEDLQEYVEILKAELEASKKREK 2115 6666677777777777777777777788888888888888888877777666655 PP == domain 18 score: -12.1 bits; conditional E-value: 4 CEP209_CC5 11 kiqeeakkveeerrraedraqelelklkgLeeLlstlkD.akGaqkvteWhk....kl..eeirlqelkknRelvkqkeeikylknl.veeqer 96 k ee++k++ + ++e+r ++l ++ +e+L + l + + G+ eW k+ e++r e ++++ + k+ ylk ++e e FUN_001422-T3 2219 KEMEEVEKLKAANANLEQRKEDL---VREMEQLQQKLTNsNMGTLDSKEWKSvvlpKIyeEKMRKLEAELEKKTNLLKDIKTYLKAAaNRETEL 2309 23344444444444444444444...33445555555441457777777764222233112333333344455555555555665441233444 PP CEP209_CC5 97 tis 99 t + FUN_001422-T3 2310 TNK 2312 332 PP == domain 19 score: -8.5 bits; conditional E-value: 4 CEP209_CC5 4 kLqedkakiqeeakkveeerrraedraqelelklkgLeeLlstlkDakGaqkv.teWhkkleeirlqelkknRelvkqkeeikylknl 90 kL+ + k + k +++ + a +r +el k++ Lee ++ l+ k ++ k ++++rl+ ++ e ++ e++ l+++ FUN_001422-T3 2280 KLEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELEEKVAILERFPTNIKSdSDLVKEFQQTRLRVATLESEKEEILHEVRQLRKM 2367 5555555555556666677778888888888899999988888876544433214556666666665555555555555555555555 PP == domain 20 score: -3.6 bits; conditional E-value: 2.5 CEP209_CC5 28 draqelelklkgLeeLlstlkDakGaqkvteWhkkleeirlqelkknRelvkqkeei 84 ++a +l l++ e L + +k k +e ++l+++ l +++ e++k + e+ FUN_001422-T3 2368 GQAGDLPRDLENDEVLEKLIKYDKMMTDDVELRTRLKTVELERDRLSHEITKLRKEL 2424 344444444444444444455555555556777777777777777777777665554 PP >> PRKG1_interact cGMP-dependent protein kinase interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 11.8 0.043 2.8e+02 6 87 .. 136 225 .. 131 226 .. 0.73 2 ! 5.6 8.4 0.0053 34 10 73 .. 217 284 .. 213 289 .. 0.79 3 ! 5.2 2.9 0.0073 47 8 76 .. 264 333 .. 259 347 .. 0.91 4 ? -4.5 11.5 4 2.6e+04 18 91 .. 346 424 .. 317 436 .. 0.50 5 ? -2.2 9.1 1.5 9.4e+03 8 91 .. 485 541 .. 448 554 .. 0.54 6 ! 6.5 5.0 0.0028 18 11 53 .. 595 637 .. 567 651 .. 0.63 7 ! 4.9 1.7 0.0089 57 4 50 .. 689 735 .. 682 743 .. 0.70 8 ? -2.8 4.2 2.3 1.5e+04 22 74 .. 779 834 .. 764 852 .. 0.63 9 ? -7.4 13.1 4 2.6e+04 22 92 .. 846 910 .. 808 918 .. 0.52 10 ! 5.4 6.3 0.0063 40 17 77 .. 945 1005 .. 929 1018 .. 0.83 11 ? -2.9 9.2 2.3 1.5e+04 16 88 .. 1040 1102 .. 1028 1109 .. 0.53 12 ? -0.0 9.0 0.31 2e+03 17 71 .. 1120 1178 .. 1106 1190 .. 0.73 13 ? -1.1 3.4 0.65 4.1e+03 18 71 .. 1204 1258 .. 1194 1270 .. 0.80 14 ? -6.7 15.2 4 2.6e+04 13 80 .. 1282 1318 .. 1231 1383 .. 0.52 15 ? 3.3 9.4 0.028 1.8e+02 5 88 .. 1391 1489 .. 1387 1492 .. 0.83 16 ? -5.8 9.6 4 2.6e+04 16 67 .. 1519 1568 .. 1503 1619 .. 0.62 17 ? -5.8 15.1 4 2.6e+04 12 76 .. 1635 1700 .. 1628 1712 .. 0.66 18 ? -2.2 12.9 1.4 9e+03 14 81 .. 1716 1796 .. 1708 1805 .. 0.59 19 ? -4.3 16.8 4 2.6e+04 11 82 .. 1805 1877 .. 1800 1885 .. 0.81 20 ? -2.8 10.1 2.3 1.5e+04 12 92 .. 1914 2000 .. 1910 2005 .. 0.48 21 ? -6.9 12.1 4 2.6e+04 8 89 .. 1992 2072 .. 1978 2078 .. 0.40 22 ! 19.5 5.0 2.5e-07 0.0016 5 90 .. 2078 2159 .. 2074 2160 .. 0.91 23 ? 2.6 12.0 0.048 3e+02 6 98 .. 2165 2247 .. 2163 2256 .. 0.70 24 ? -5.0 8.3 4 2.6e+04 14 52 .. 2279 2317 .. 2270 2380 .. 0.54 25 ? 0.3 1.7 0.25 1.6e+03 6 42 .. 2389 2425 .. 2383 2463 .. 0.71 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.043 PRKG1_interact 6 yekalqenerLkekleelkkelaeiksklekvk.q.....kqeslskrssl..lelekrE.kralerkiseleeelkvleeLkaeNqrLkd 87 + +++++n++L ++l+ +++e +++k l++ k +q ++r+s+ + E k +l +k el e l ++ L+ N+ L + FUN_001422-T3 136 FFQEKNKNDQLANRLDAAERENKSLKRDLDRGKlDlrdlqRQ-FEQQRESMviRRGGDSEfKDKLSKKNKELSEYLDEIRVLQEANDELEE 225 788999999999999999999999999999887435554222.22233333113334444388999********************99965 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0053 PRKG1_interact 10 lqenerLkekleelkkelaeiksklekvkq...kqesl.skrssllelekrEkralerkiseleeelk 73 ++ n++L e++++++kel+e++++++k+++ k + + +++ +++ ++E+ al ++++l ++ FUN_001422-T3 217 QEANDELEERIKDVQKELEESTEEMNKMTEectKLKTIlQQSDLIIDDMRKERDALRAQVQDLRMQFA 284 56799***********************95355555551445556677899**********9988765 PP == domain 3 score: 5.2 bits; conditional E-value: 0.0073 PRKG1_interact 8 kalqenerLkekleelkkelaeiksklekvk.qkqeslskrssllelekrEkralerkiseleeelkvle 76 + ++e + L+ ++++l+++ a+ + + + + + ++++ +++l +++ E ++++ + el++++ l+ FUN_001422-T3 264 DMRKERDALRAQVQDLRMQFANKTDTDDDIMvAVNAKVEEWKAVLAAKEIELEQYKSLVEELQQQITGLQ 333 67999******************99999999557889***************************998775 PP == domain 4 score: -4.5 bits; conditional E-value: 4 PRKG1_interact 18 ekleelkkelaeiksklekvkqkqe...slskrssllelekrEkralerkiseleeelk..vleeLkaeNqrLkdENgA 91 ++++e +++++ ++++lek++++ + s +++ + l+ + + +++i el++ l+ +le+L ++ + +E +A FUN_001422-T3 346 QEVKEKDEKIEMLQKELEKAASEMHgvaSYAEQVKSLSEKGVPSAYQQKRIKELNSTLQreQLESLEVKDRMIMAEEAA 424 3444444444444444444432221222344444444444445555566666666655322555666555555554444 PP == domain 5 score: -2.2 bits; conditional E-value: 1.5 PRKG1_interact 8 kalqenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgA 91 +a ene+L+e+l ke+ +i+ +k k + e+ + ++L +e +rL +E FUN_001422-T3 485 DAEMENEELRERLGMDPKEKLDIEDVRHKKK---------------------------VKAEQAIALNRALNKEVERLEEERLQ 541 4455666666666554444444444333333...........................33333333333333333333333322 PP == domain 6 score: 6.5 bits; conditional E-value: 0.0028 PRKG1_interact 11 qenerLkekleelkkelaeiksklekvkqkqeslskrssllel 53 + n+rL ++e++++++++ k++++k+++++++l+++++ le+ FUN_001422-T3 595 AVNKRLEGEVEKSEQQIEKFKTNMKKIESENKELKDENKQLEV 637 3455555555555555555555555555555555555555555 PP == domain 7 score: 4.9 bits; conditional E-value: 0.0089 PRKG1_interact 4 klyekalqenerLkekleelkkelaeiksklekvkqkqeslskrssl 50 + e+ ne+L+++l+++++e a+ +++e+ + k e l+k+ ++ FUN_001422-T3 689 AQIEQLSGRNEELRHELHNAREETAKAVMQVERKNTKIEDLEKEVQV 735 44566666788888888888888888888888877666666655444 PP == domain 8 score: -2.8 bits; conditional E-value: 2.3 PRKG1_interact 22 elkkelaeiksklekvkqkqeslskrssllele...krEkralerkiseleeelkv 74 ++ la++++ le k k + +++ ll ++ ++Ek+ er++s+ e+ + FUN_001422-T3 779 LKEELLAKMEKDLELFKRKVSVILHQKGLLYADylrEKEKWDEERRASDEEKASME 834 33445666777777776666655555555544322278999999999998876544 PP == domain 9 score: -7.4 bits; conditional E-value: 4 PRKG1_interact 22 elkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgAL 92 e ++ l+++ + +k k++ +++++ + + + +++l r+ + ++e v ++L++eN++ +++ A+ FUN_001422-T3 846 EFERLLDTLDKDEDKQKKRLSEMARKVT---VLRVNEKSLSRRYTAMQE---VETALRKENKKFRNDVVAM 910 3333333333333333333333333333...333344566666666654...4556666666666655555 PP == domain 10 score: 5.4 bits; conditional E-value: 0.0063 PRKG1_interact 17 kekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvlee 77 ++le ++k+ +e+++k + q+++sl +rs++++ + +k+ le +el++e+ +l+e FUN_001422-T3 945 ASELEAANKQYNELTAKYRDIIQRENSLVARSAIVDSLEADKKLLEETEVELKKEMTALKE 1005 5799********************************************9999999987765 PP == domain 11 score: -2.9 bits; conditional E-value: 2.3 PRKG1_interact 16 LkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdE 88 + +kl +l+++ +++++ ++++ + + ++le + sele+++ +++L e qr+ E FUN_001422-T3 1040 ISRKLATLEMKELNERERADHAT----------RKYDQLQSLVQQLEERNSELEHKFAEISNLNLESQRIERE 1102 33333333333333333333332..........2222223334677777777888888888888777776655 PP == domain 12 score: -0.0 bits; conditional E-value: 0.31 PRKG1_interact 17 kekleelkkelaeiksklekvkq....kqeslskrssllelekrEkralerkiseleee 71 +++++l+++ +++k++++++k+ ++++++ ++ e +++E +l +++ +++ e FUN_001422-T3 1120 TRRVQSLEESESKLKVEVSRLKEvaevASHQTEAIKAQQESQDKELTSLRKQLYDMQME 1178 46667777777777776666664233355678888899999999*********999977 PP == domain 13 score: -1.1 bits; conditional E-value: 0.65 PRKG1_interact 18 ekleelkkelaeiksklekvkqkqeslskrssllelekrEkra.lerkiseleee 71 +kle + ++l+++++ + +++qk ++ ++ +++e r k + l++ i++l ++ FUN_001422-T3 1204 RKLEAATQKLSRQEALVLRLEQKIDEKDQALYHAKMEARNKAKfLKKTIQDLRRQ 1258 7899999999999999999999999999999999999888866256667777665 PP == domain 14 score: -6.7 bits; conditional E-value: 4 PRKG1_interact 13 nerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLka 80 ++L ++l+ k++++a e +++el+ + l+eL a FUN_001422-T3 1282 KRTLERELK-------------------------------KAKNDREAAEDRLAELKLQHDGLQELMA 1318 222233333...............................3345555555555555555555555543 PP == domain 15 score: 3.3 bits; conditional E-value: 0.028 PRKG1_interact 5 lyekalqenerLkekleelkkelaeiksklekvk.qkqe..............slskrssllelekrEkralerkiseleeelkvleeLkaeN 82 ++e+ e er+ +kle+ ++elae ++k+e+++ + + +++++ ++ ++E+++l++k el+ +k+ ee ++ FUN_001422-T3 1391 IWEQREVELERMIDKLEKQQRELAEAATKFEEATgSIPDpnlpvanqlemaisKIKEHIRTIVGTREENKQLKKKHNELDLAFKQSEERLTQK 1483 799999**************************9954233667777788888877777778888889999999999999999999998877777 PP PRKG1_interact 83 qrLkdE 88 ++L +E FUN_001422-T3 1484 DKLINE 1489 777666 PP == domain 16 score: -5.8 bits; conditional E-value: 4 PRKG1_interact 16 LkekleelkkelaeiksklekvkqkqeslskrssllelekrEkr.alerkise 67 k+ l+ ++ ++++++ l + k+esl+k +++l+ ++E + + e++ +e FUN_001422-T3 1519 TKRALKVAQATVSSLQQMLAH---KEESLNKYQAMLKEAREEAKtQSEQHKVE 1568 333333333333333333333...56666666666665555533133333333 PP == domain 17 score: -5.8 bits; conditional E-value: 4 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkise.leeelkvle 76 ++ +e +e ++++++ k+++ + ++++ + k+ + ++e+ E+ + k++e l++el++ + FUN_001422-T3 1635 SRNEVMETKKEHEEDVENFKQQMTRKDEEHSNELKKITSEKMERDERIMEQSKMIEvLKDELETAK 1700 333444444666677777777777766666677777777888888888777777773566666655 PP == domain 18 score: -2.2 bits; conditional E-value: 1.4 PRKG1_interact 14 erLkekleelkkelaeiksklekvkq....kqe.........slskrssllelekrEkralerkiseleeelkvl.eeLkae 81 erL+++l +k+++++ + l +++ + +++ + ++ ++E l+ +i el+e ++++ +eL+++ FUN_001422-T3 1716 ERLRNQLALKEKQQKSLSQALLQLRAdmvsT-AeenvqaharRAEEQANVQHVVDKETTGLQSRIEELQERMEKFkKELRKQ 1796 4455444433333333333333332111110.0223334444889999999999***************9997761456654 PP == domain 19 score: -4.3 bits; conditional E-value: 4 PRKG1_interact 11 qenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvlee.LkaeN 82 e ++Lk+ l + + l + +l++++ qe+l+k+ + l +ek+ + + i +l e++k l+e Lk+e FUN_001422-T3 1805 GEKDKLKQDLSKKDAALLKFGRELKELETVQEQLEKKDQELRIEKNKHAQERSEIENLREKVKSLQEkLKQER 1877 6889999999999999999999999999889999999999999998877777788899999998874366665 PP == domain 20 score: -2.8 bits; conditional E-value: 2.3 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqeslskrssllelek.....rEkralerkiseleeel...kvleeLkaeNqrLkdENgAL 92 +n++ ++k+e+lk +lae + +lek+++++ l + +e +k r k +++ + +e ++ +v+++Lk +L +EN+ L FUN_001422-T3 1914 DNKKWQQKVETLKGKLAEKTRELEKAQKSNAMLREALNRAEKDKaglhsRLKSSVKAGV--VEPSVvtnEVVQDLKHSIFKLEEENQEL 2000 67777777777777777777777776543332222222222222000002222222223..3332211255666776666666666555 PP == domain 21 score: -6.9 bits; conditional E-value: 4 PRKG1_interact 8 kalqenerLkek.leelkkelaeiksklekvkqkqe....slskrssllelekrEkralerkiseleeelkvlee.LkaeNqrLkdEN 89 k +en++L+++ + +++e ++ +++ + + + l E+r+ +r +++ +el++ ++ L+++ k+EN FUN_001422-T3 1992 KLEEENQELRREkVLG-------HDKQMEALELRNRqqmeYIGRLERDLAERAAEERSFDRADADMYRELHQRNQyLQKQLLEVKEEN 2072 4444444444220111.......11222222222220000222222222223344455555555555555544321444444555555 PP == domain 22 score: 19.5 bits; conditional E-value: 2.5e-07 PRKG1_interact 5 lyekalqenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENg 90 ye+a++en rLk ++e+l++ ++ +k++le +k k+e+ k++ + + + + +er i+ + +v+e+L+ eN++Lk g FUN_001422-T3 2078 EYEQARKENPRLKARVEDLQEYVEILKAELEASK-KREKARKKNLGTGMGGQSVEDMERVIAAMR---RVVERLQGENDQLKKSVG 2159 59*****************************987.688999999999****************98...6889999******98666 PP == domain 23 score: 2.6 bits; conditional E-value: 0.048 PRKG1_interact 6 yekalqenerLkekleelkkelaeiksklekvkqkqeslskrssllelekrEkralerkiseleeelkvleeLkaeNqrLkdENgALiRVisk 98 y + +en+rLk++l+++k ++ + ++ + s+ +++ + + e+ + +l++e++ +e+Lka N L + L+R + + FUN_001422-T3 2165 YGEVIKENKRLKQELDKAKGASVKTGGQSSRGVN----ASA-NTTKLMAE-----NEKLLKNLKKEMEEVEKLKAANANLEQRKEDLVREMEQ 2247 6778899999999999998888777777766432....111.11122222.....34557788889999999999999998888888886655 PP == domain 24 score: -5.0 bits; conditional E-value: 4 PRKG1_interact 14 erLkekleelkkelaeiksklekvkqkqeslskrsslle 52 ++L +le+ + l++ik+ l+ +++++ +l++++ le FUN_001422-T3 2279 RKLEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELE 2317 344444444444444444444444433333222222211 PP == domain 25 score: 0.3 bits; conditional E-value: 0.25 PRKG1_interact 6 yekalqenerLkekleelkkelaeiksklekvkqkqe 42 y k ++ +L+++l++++ e +++ +++ k++++ e FUN_001422-T3 2389 YDKMMTDDVELRTRLKTVELERDRLSHEITKLRKELE 2425 7788888999999999999999999999999875444 PP >> DUF7801 Domain of unknown function (DUF7801) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 4.8 0.34 2.2e+03 53 131 .. 45 128 .. 37 144 .. 0.72 2 ? -3.0 4.4 1.7 1.1e+04 60 108 .. 113 161 .. 108 185 .. 0.66 3 ! 17.4 22.1 8.5e-07 0.0054 59 152 .. 193 282 .. 138 284 .. 0.84 4 ? 2.7 6.0 0.029 1.8e+02 56 111 .. 309 369 .. 299 379 .. 0.75 5 ? -3.6 8.5 2.5 1.6e+04 3 85 .. 348 432 .. 346 457 .. 0.59 6 ? -10.6 19.8 4 2.6e+04 7 145 .. 473 624 .. 466 629 .. 0.66 7 ? -1.1 5.2 0.44 2.8e+03 63 109 .. 598 644 .. 581 658 .. 0.70 8 ! 7.6 3.7 0.00091 5.8 57 105 .. 686 734 .. 674 741 .. 0.89 9 ? -2.6 6.3 1.2 7.8e+03 54 128 .. 831 903 .. 821 908 .. 0.71 10 ? -10.7 19.7 4 2.6e+04 46 137 .. 902 998 .. 852 1016 .. 0.53 11 ? -0.8 13.1 0.33 2.1e+03 56 148 .. 994 1088 .. 987 1093 .. 0.79 12 ? -1.4 10.0 0.53 3.4e+03 56 132 .. 1031 1111 .. 1024 1115 .. 0.67 13 ? 1.8 5.5 0.054 3.4e+02 57 110 .. 1118 1171 .. 1110 1181 .. 0.81 14 ? -6.5 9.9 4 2.6e+04 77 147 .. 1225 1290 .. 1193 1312 .. 0.48 15 ? -0.5 2.7 0.27 1.7e+03 58 110 .. 1271 1322 .. 1261 1331 .. 0.73 16 ? -0.2 11.4 0.23 1.5e+03 57 142 .. 1331 1413 .. 1322 1422 .. 0.83 17 ? -4.1 10.4 3.6 2.3e+04 47 105 .. 1520 1577 .. 1474 1585 .. 0.79 18 ? -7.9 15.9 4 2.6e+04 58 108 .. 1650 1700 .. 1611 1723 .. 0.66 19 ? -6.6 31.6 4 2.6e+04 8 151 .. 1720 1878 .. 1713 1882 .. 0.72 20 ? 0.1 2.6 0.18 1.1e+03 88 117 .. 1913 1942 .. 1894 1967 .. 0.56 21 ? -7.7 11.9 4 2.6e+04 9 97 .. 1921 2021 .. 1913 2046 .. 0.47 22 ? 2.2 13.8 0.04 2.5e+02 46 127 .. 2034 2115 .. 2031 2155 .. 0.83 23 ? 0.4 11.0 0.15 9.7e+02 35 105 .. 2176 2253 .. 2166 2279 .. 0.68 24 ? -4.1 5.8 3.6 2.3e+04 74 102 .. 2290 2318 .. 2258 2355 .. 0.50 25 ? -3.6 17.4 2.5 1.6e+04 60 146 .. 2345 2431 .. 2279 2437 .. 0.77 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.34 DUF7801 53 aanpaiqk.eldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeelt.....kasielEkeRekleel 131 an +iq e+ + k ++l++elaa + ++ +++++el +++ Le EL+ + y+ + ++ ++E R+ le+ FUN_001422-T3 45 DANMMIQLfEVTKAVMKVKSLQAELAADEMHQGGGGEREQELVDEIAHLEGELQRY-QKYDGMGgedfmREIRQIENSRNALERE 128 455555533788888899999****999988888999999*************975.6676664111115555666777776654 PP == domain 2 score: -3.0 bits; conditional E-value: 1.7 DUF7801 60 keldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELreti 108 +e+ +++++ ++le+el++ +++ ++++++ +l++r +a e+E + + FUN_001422-T3 113 REIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLK 161 6777777777777777777666656666666667777776666655444 PP == domain 3 score: 17.4 bits; conditional E-value: 8.5e-07 DUF7801 59 qkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaqlsdekvk 152 ++ d+L++kn+el+e l++++ +e ++ el+er+k ++kEL+e +ee +++t + +l ++ + +iD++r++ ++L aq++d +++ FUN_001422-T3 193 SEFKDKLSKKNKELSEYLDEIRVLQE----ANDELEERIKDVQKELEESTEEMNKMTEECTKLKTILQQSDLIIDDMRKERDALRAQVQDLRMQ 282 444599***************98765....567899******************************************************9987 PP == domain 4 score: 2.7 bits; conditional E-value: 0.029 DUF7801 56 paiqkeldeLkaknaeleeelaaLkaekeak.....eaesaelqervkaLekELretieey 111 +a + el++ k+ +el+++++ L+ + ++ ++e +e++e++++L+kEL++ ++e FUN_001422-T3 309 AAKEIELEQYKSLVEELQQQITGLQLDADKGslamlHQEVKEKDEKIEMLQKELEKAASEM 369 45567888999999999999999886554331222256778999***********998875 PP == domain 5 score: -3.6 bits; conditional E-value: 2.5 DUF7801 3 reeaeeeleklekEleelesevvrlqteltlakA....eLdgAYGsraeRaaevaanpaiq.keldeLkaknael.eeelaaLkaekea 85 +e++e++e l+kEle++ se+ + +k+ +AY + R +e n+++q ++l++L+ k++ + +ee aaLk ++ + FUN_001422-T3 348 VKEKDEKIEMLQKELEKAASEMHGVASYAEQVKSlsekGVPSAYQQK--RIKEL--NSTLQrEQLESLEVKDRMImAEEAAALKDKQLN 432 45677788888888888888877666555555541100344444333..55554..444441457888877765415777778776644 PP == domain 6 score: -10.6 bits; conditional E-value: 4 DUF7801 7 eeeleklekEleelesevvrlqteltla.kAeLdgA...YGsraeRaaevaanpaiqkeldeLkaknaeleeela..aLkaekeakeae..s.... 90 ++++++le E++++e+e l+ l + k Ld + + + + +a+n a++ke+++L+++ +l+++l aL++ +a e + + FUN_001422-T3 473 TSQINNLEIEVNDAEMENEELRERLGMDpKEKLDIEdvrHKKKVKAEQAIALNRALNKEVERLEEERLQLKRQLRkqALHRGARAVELGitAedli 568 6778889999999999999999999995355566531113334344445689*******************9996224555443332221121111 PP DUF7801 91 aelqervkaLekELretieeyeeltkas.ielEkeRekleeliDslrdrceqLeaq 145 +e+v + L + ++ e+tka +lE e ek e+ i +++ ++ ++e++ FUN_001422-T3 569 MAEEENVVSAPRRLPHATDSDSEVTKAVnKRLEGEVEKSEQQIEKFKTNMKKIESE 624 22344555555678888888888888751467888888888888888888888876 PP == domain 7 score: -1.1 bits; conditional E-value: 0.44 DUF7801 63 deLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretie 109 ++L+ + ++ e++++++k++ ++ e+e++el+++ k+Le +re+++ FUN_001422-T3 598 KRLEGEVEKSEQQIEKFKTNMKKIESENKELKDENKQLEVGMREILA 644 34555556667778888888888888888888888888887777765 PP == domain 8 score: 7.6 bits; conditional E-value: 0.00091 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELr 105 ++++++++L+ +n+el +el++ ++e++++ ++ + ++ +++ LekE + FUN_001422-T3 686 QLKAQIEQLSGRNEELRHELHNAREETAKAVMQVERKNTKIEDLEKEVQ 734 67899********************9999999999999*********87 PP == domain 9 score: -2.6 bits; conditional E-value: 1.2 DUF7801 54 anpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekl 128 a ++++e d++ + e+e+ l++L +++++++++ +e++++v++L+ + + + y ++ l ke +k+ FUN_001422-T3 831 ASMELSREHDKI--RLLEFERLLDTLDKDEDKQKKRLSEMARKVTVLRVNEKSLSRRYTAMQEVETALRKENKKF 903 444555566655..4456677788999888888888899999999999888888888888888777777777776 PP == domain 10 score: -10.7 bits; conditional E-value: 4 DUF7801 46 aeRaaevaanpaiqkeldeLkaknaeleeelaaLkaekeak.eaes.aelqervkaLekELretie.eyeeltkasi..elEkeRekleeliDslr 136 + R va++ ai++ l L+++++ + ++++L+++ +++ +a++ + ++++ + L r++i+ e +++++i lE +++ lee+ +l+ FUN_001422-T3 902 KFRNDVVAMETAISERLGYLQRHKEMSTYKISVLQQALDESvQASElEAANKQYNELTAKYRDIIQrENSLVARSAIvdSLEADKKLLEETEVELK 997 335555666667777777776666666667777766544331222213344555666666666665244444555553334555555555433333 PP DUF7801 137 d 137 + FUN_001422-T3 998 K 998 3 PP == domain 11 score: -0.8 bits; conditional E-value: 0.33 DUF7801 56 paiqkeldeLkaknaeleeelaaLkaekeak..eaesaelqervkaLekELret.ieeyeeltkasielEkeRekleeliDslrdrceqLeaql 146 +++ke+ +Lk++n++le+ l+ L ++ + +++s+ qe+++ + + L+ + ++e +e +a ++ + ++l++l+ +l +r +Le ++ FUN_001422-T3 994 VELKKEMTALKERNHSLEQMLNDLLSKDGGQggADTSSVRQEEIDRISRKLATLeMKELNERERAD-HATRKYDQLQSLVQQLEERNSELEHKF 1086 5789*******************9887654411344556688889999999865367777766665.4556789*****************998 PP DUF7801 147 sd 148 ++ FUN_001422-T3 1087 AE 1088 76 PP == domain 12 score: -1.4 bits; conditional E-value: 0.53 DUF7801 56 paiqkeldeLkaknaele.eelaaLkaekeakeaesaelqervkaLe...kELretieeyeeltkasielEke.Rekleeli 132 ++ q+e+d++++k a+le +el++ ++ ++++++ +lq+ v++Le +EL++ +e +l +s ++E+e Re+l + + FUN_001422-T3 1031 SVRQEEIDRISRKLATLEmKELNER-ERADHATRKYDQLQSLVQQLEernSELEHKFAEISNLNLESQRIERElREELSNSV 1111 5679999999999888853444442.22333444556677777777622258888888888888888888888777777655 PP == domain 13 score: 1.8 bits; conditional E-value: 0.054 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretiee 110 ++++ +++L++++++l+ e++ Lk+ e ++++++ ++ +++ kEL+ + ++ FUN_001422-T3 1118 SVTRRVQSLEESESKLKVEVSRLKEVAEVASHQTEAIKAQQESQDKELTSLRKQ 1171 5678999*****************998888888888888888888888876655 PP == domain 14 score: -6.5 bits; conditional E-value: 4 DUF7801 77 aaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaqls 147 +++ ++ +a +++ e+++++k L+k ++++ ++y ++ l k ek+ e++ +l+d++ +Le +l FUN_001422-T3 1225 QKIDEKDQALYHAKMEARNKAKFLKKTIQDLRRQYS----GALPLMK-QEKFAETMRTLHDDKRTLERELK 1290 223333334444556666666666666666666664....3333333.23444444444444444444443 PP == domain 15 score: -0.5 bits; conditional E-value: 0.27 DUF7801 58 iqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretiee 110 + + +L++ +++le+el++ k+++ea+e++ ael+ + + L+ EL +t+++ FUN_001422-T3 1271 FAETMRTLHDDKRTLERELKKAKNDREAAEDRLAELKLQHDGLQ-ELMATLKD 1322 45667778888888888888888888888888888777777774.66666655 PP == domain 16 score: -0.2 bits; conditional E-value: 0.23 DUF7801 57 aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqL 142 + ++++ eL+ ++ +l++ ++ L++e + e+ + +++ ++ Le E ++++e+e+ + +E+ +le++iD+l ++ +L FUN_001422-T3 1331 EWHAKMGELRLQDLKLNRAVTRLQEELKYLENVVKVHERSISDLEDENVQMAKEHED---RQLIWEQREVELERMIDKLEKQQREL 1413 5677888999999999999***999998888888888888999***********997...45669999999********8877666 PP == domain 17 score: -4.1 bits; conditional E-value: 3.6 DUF7801 47 eRaaevaanpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELr 105 +Ra +va +++++ + L++k+++l++ a+Lk+++e+++++s++++ +++ L+ L+ FUN_001422-T3 1520 KRALKVAQ-ATVSSLQQMLAHKEESLNKYQAMLKEAREEAKTQSEQHKVEIQLLQDRLH 1577 36766664.34555557788899999999999999999999998888888888887775 PP == domain 18 score: -7.9 bits; conditional E-value: 4 DUF7801 58 iqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELreti 108 +++ +++++k++e ++el+++++ek +++++ e+++ +++L+ EL+ FUN_001422-T3 1650 VENFKQQMTRKDEEHSNELKKITSEKMERDERIMEQSKMIEVLKDELETAK 1700 222234566777888888888888888888888888888888888887654 PP == domain 19 score: -6.6 bits; conditional E-value: 4 DUF7801 8 eeleklekEleelesevvrlqteltlakAeLdgAYGsraeRaaevaa.....npaiqkeldeLkaknaeleeelaaLkaekea....keaesae 92 ++l+ +ek ++l++ + +l++++ + e A+ rae +a+v+ +q+ ++eL+++ +++++el + + +++a k++ +++ FUN_001422-T3 1720 NQLALKEKQQKSLSQALLQLRADMVSTAEENVQAHARRAEEQANVQHvvdkeTTGLQSRIEELQERMEKFKKELRKQRDKETAllgeKDKLKQD 1813 5666777888889999999999987777777789*9****999997422222456778888888888888888887776654311113444566 PP DUF7801 93 lqervkaLe...kELretieeyeeltka..sielEkeRekle.eliDslrdrceqLeaqlsdekv 151 l+++ aL +EL+e+ + e+l k+ +++Ek+++ e + i +lr+++ +L+++l +e+ FUN_001422-T3 1814 LSKKDAALLkfgRELKELETVQEQLEKKdqELRIEKNKHAQErSEIENLREKVKSLQEKLKQERK 1878 666666553133799999888889988622677899998888357****************9995 PP == domain 20 score: 0.1 bits; conditional E-value: 0.18 DUF7801 88 aesaelqervkaLekELretieeyeeltka 117 +++++ q++v++L+ L+e ++e e+ k+ FUN_001422-T3 1913 EDNKKWQQKVETLKGKLAEKTRELEKAQKS 1942 445555555555555555555555543332 PP == domain 21 score: -7.7 bits; conditional E-value: 4 DUF7801 9 eleklekEleelesevvrlqteltl.....akAeLdgA.YGsraeRaaevaa.np..aiqkeldeLkaknaeleeelaaLkaek...eakeaes 90 ++e+l+ l+e e+ ++q ++ +Ae d A sr + ++++ +p ++++ +++Lk++ +leee ++L++ek ++k++e+ FUN_001422-T3 1921 KVETLKGKLAEKTRELEKAQKSNAMlrealNRAEKDKAgLHSRLKSSVKAGVvEPsvVTNEVVQDLKHSIFKLEEENQELRREKvlgHDKQMEA 2014 3444444444444444444443333000003455554422344333322221123113345567787777888888888877763322333344 PP DUF7801 91 aelqerv 97 el++r+ FUN_001422-T3 2015 LELRNRQ 2021 4444444 PP == domain 22 score: 2.2 bits; conditional E-value: 0.04 DUF7801 46 aeRaaev.aanpaiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELretieeyeeltkasielEkeRek 127 aeRaae + + a + eL+++n+ l+++l ++k+e+ + + e ++++++ L+ ++ ++ey e+ ka +e+ k Rek FUN_001422-T3 2034 AERAAEErSFDRADADMYRELHQRNQYLQKQLLEVKEENMELRFEYEQARKENPRLKARVED-LQEYVEILKAELEASKKREK 2115 78888762456666666788999999999999999998888888888888888889988877.58899999999999999987 PP == domain 23 score: 0.4 bits; conditional E-value: 0.15 DUF7801 35 kAeLdgAYGs......raeRaaevaanp.aiqkeldeLkaknaeleeelaaLkaekeakeaesaelqervkaLekELr 105 k eLd A G+ ++ R +++an ++ +e ++L ++ ++ ee+++Lka++++ e+++++l +++++L++ L+ FUN_001422-T3 2176 KQELDKAKGAsvktggQSSRGVNASANTtKLMAENEKLLKNLKKEMEEVEKLKAANANLEQRKEDLVREMEQLQQKLT 2253 455555555411111155566666555414566777776666666677888888877778888888888888887776 PP == domain 24 score: -4.1 bits; conditional E-value: 3.6 DUF7801 74 eelaaLkaekeakeaesaelqervkaLek 102 + l+ +k+ +a++++++el+++++ Le+ FUN_001422-T3 2290 NLLKDIKTYLKAAANRETELTNKQHELEE 2318 22222222223333333333333333332 PP == domain 25 score: -3.6 bits; conditional E-value: 2.5 DUF7801 60 keldeLkaknaeleeelaaLkaekeak.eaesaelqervkaLekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaql 146 + +L+++++e+ +e+ +L++ +a ++ e +e ++L k + ++++ e t+ +E eR++l + i +lr++ e+++ + FUN_001422-T3 2345 LRVATLESEKEEILHEVRQLRKMGQAGdLPRDLENDEVLEKLIKYDKMMTDDVELRTRLK-TVELERDRLSHEITKLRKELEAFDPAF 2431 457789999***********9976655145677778888888888899999999999964.456677789999*********988665 PP >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -5.3 14.7 4 2.6e+04 21 105 .. 85 180 .. 79 207 .. 0.56 2 ? 2.8 23.8 0.026 1.6e+02 10 138 .. 197 332 .. 192 334 .. 0.81 3 ? -8.8 18.8 4 2.6e+04 51 114 .. 345 412 .. 300 436 .. 0.44 4 ? -3.6 18.3 2.4 1.5e+04 35 135 .. 443 539 .. 419 551 .. 0.65 5 ! 4.4 5.6 0.008 51 47 90 .. 590 633 .. 582 652 .. 0.58 6 ! 16.5 5.1 1.4e-06 0.0092 55 107 .. 685 737 .. 655 741 .. 0.86 7 ? -4.0 4.3 3.1 2e+04 63 129 .. 765 834 .. 760 842 .. 0.69 8 ? -9.2 19.1 4 2.6e+04 13 117 .. 824 931 .. 811 957 .. 0.66 9 ? -4.9 10.1 4 2.6e+04 53 90 .. 978 1015 .. 936 1020 .. 0.58 10 ? 0.0 11.4 0.18 1.2e+03 58 112 .. 1034 1088 .. 1027 1115 .. 0.75 11 ? -0.6 21.3 0.29 1.8e+03 4 138 .. 1115 1255 .. 1112 1257 .. 0.86 12 ! 8.1 18.3 0.00059 3.7 4 127 .. 1267 1388 .. 1266 1399 .. 0.82 13 ? -8.1 9.8 4 2.6e+04 24 42 .. 1404 1422 .. 1392 1513 .. 0.42 14 ? -9.6 19.9 4 2.6e+04 78 139 .. 1512 1573 .. 1438 1576 .. 0.70 15 ? -5.0 16.1 4 2.6e+04 11 110 .. 1522 1625 .. 1513 1638 .. 0.63 16 ? -9.7 25.0 4 2.6e+04 45 134 .. 1638 1721 .. 1606 1726 .. 0.67 17 ? -5.8 13.4 4 2.6e+04 26 97 .. 1689 1765 .. 1677 1767 .. 0.73 18 ? -14.3 40.7 4 2.6e+04 10 140 .] 1720 1871 .. 1715 1875 .. 0.66 19 ? -2.6 14.0 1.2 7.6e+03 32 84 .. 1830 1882 .. 1818 1900 .. 0.56 20 ? -7.5 17.8 4 2.6e+04 13 117 .. 1916 2035 .. 1911 2046 .. 0.67 21 ! 12.5 12.5 2.5e-05 0.16 21 123 .. 2053 2157 .. 2045 2164 .. 0.91 22 ? -0.7 13.7 0.29 1.9e+03 75 124 .. 2203 2252 .. 2164 2263 .. 0.68 23 ? 0.2 12.5 0.16 1e+03 23 108 .. 2275 2359 .. 2272 2367 .. 0.83 24 ? 3.1 1.9 0.02 1.3e+02 8 37 .. 2399 2428 .. 2378 2467 .. 0.59 Alignments for each domain: == domain 1 score: -5.3 bits; conditional E-value: 4 CENP-F_leu_zip 21 sLkdkvenLerelemseenq.......ekvileaEnskaevet.lkaeieelaee...lrqleldLvtlrsekeeLtkeLqkkqervseLeslns 104 L d + Le el+ ++ + i++ Ens++++e l+++ e +e ql L + +e+++L+++L + +L++ + FUN_001422-T3 85 ELVDEIAHLEGELQRYQKYDgmggedfMREIRQIENSRNALEReLNEKEEAFFQEknkNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFE 179 56777777777777665432111100034456666666666654555555554330003456666666666666666666666666666655444 PP CENP-F_leu_zip 105 s 105 + FUN_001422-T3 180 Q 180 4 PP == domain 2 score: 2.8 bits; conditional E-value: 0.026 CENP-F_leu_zip 10 ekLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslns 104 +kL + ++ + d + L+ ++ee v e E+s +e++++ +e +l++ l+q l + +r+e++ L ++q+ + + + + FUN_001422-T3 197 DKLSKKNKELSEYLDEIRVLQEANDELEERIKDVQKELEESTEEMNKMTEECTKLKTILQQSDLIIDDMRKERDALRAQVQDLRMQFANKTDTDD 291 56666666666677889999999999999999999999999999999999999999999999999999999999999999999998888888888 PP CENP-F_leu_zip 105 slenlleekEqe.......kvqmkeeskaaveeLqtqlkel 138 ++ +++ k +e k + e++k+ veeLq+q+ l FUN_001422-T3 292 DIMVAVNAKVEEwkavlaaKEIELEQYKSLVEELQQQITGL 332 88888877766666778766677788899999999988776 PP == domain 3 score: -8.8 bits; conditional E-value: 4 CENP-F_leu_zip 51 kaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkk.......qervseLeslnsslenlleekE 114 +ev++ ++ie+l++el++ +++ + s e++ k+L +k q+r++eL+s+ +++le +E FUN_001422-T3 345 HQEVKEKDEKIEMLQKELEKAASEMHGVASYAEQV-KSLSEKgvpsayqQKRIKELNSTLQ--REQLESLE 412 23444444444444444444444444444444444.3333322222222445555544432..34455555 PP == domain 4 score: -3.6 bits; conditional E-value: 2.4 CENP-F_leu_zip 35 mseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeeskaave 129 e +++++ e ++ ka++ ++ie l+++ ++le++++ e+eeL + L+ ++ L+ + ++ ++ Eq + ++ + +++ve FUN_001422-T3 443 RGEYGLSEAVQEIKDCKAQIRIRDQNIEDLTSQINNLEIEVNDAEMENEELRERLGMDPKE--KLDIEDVRHKKKVKA-EQ-AIALNRALNKEVE 533 4455678999999********************************9999999999866553..444444444444432.22.2333333333333 PP CENP-F_leu_zip 130 eLqtql 135 L+ ++ FUN_001422-T3 534 RLEEER 539 333333 PP == domain 5 score: 4.4 bits; conditional E-value: 0.008 CENP-F_leu_zip 47 aEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLq 90 +E ka + l+ e+e+ +++ ++++++++++ se++eL+ e + FUN_001422-T3 590 SEVTKAVNKRLEGEVEKSEQQIEKFKTNMKKIESENKELKDENK 633 55555555556666666666666666666666666555543322 PP == domain 6 score: 16.5 bits; conditional E-value: 1.4e-06 CENP-F_leu_zip 55 etlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnssle 107 +lka+ie+l+ + ++l+++L + r+e + +++ k+ ++++Le+ l+ FUN_001422-T3 685 LQLKAQIEQLSGRNEELRHELHNAREETAKAVMQVERKNTKIEDLEKEVQVLK 737 469*******************************************9887766 PP == domain 7 score: -4.0 bits; conditional E-value: 3.1 CENP-F_leu_zip 63 elaeelrqleldLvtlrsekeeLtkeLqkkqervse.LeslnsslenlleekEqe..kvqmkeeskaave 129 l+e+l + ++L+ + +++k+L+ +++vs L + l+ekE+ +++ +e ka++e FUN_001422-T3 765 SLNEHLIHVLQELSLKEELLAKMEKDLELFKRKVSViLHQKGLLYADYLREKEKWdeERRASDEEKASME 834 5556666666666665566678888888888888853677777788889988864337777777777776 PP == domain 8 score: -9.2 bits; conditional E-value: 4 CENP-F_leu_zip 13 KeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnssle 107 ++s ++++s++ e + l + e+ ++ + + +++k+ ++++ ++ l+ + + l+ +++++ L ke +k ++ v +e++ s+ FUN_001422-T3 824 RASDEEKASMELSREHDKIRLLEFERLLDTLDKDEDKQKKRLSEMARKVTVLRVNEKSLSRRYTAMQEVETALRKENKKFRNDVVAMETAISERL 918 33333333333333333333445677778888899999999999999999999999999999999999999999999999999999999988877 PP CENP-F_leu_zip 108 nllee.kEqe..k 117 l++ kE+ k FUN_001422-T3 919 GYLQRhKEMStyK 931 7776426666441 PP == domain 9 score: -4.9 bits; conditional E-value: 4 CENP-F_leu_zip 53 evetlkaeieelaeelrqleldLvtlrsekeeLtkeLq 90 v +l+a ++ l+e+ +l+ ++++l++++ +L+++L+ FUN_001422-T3 978 IVDSLEADKKLLEETEVELKKEMTALKERNHSLEQMLN 1015 23345555555555555555555555555555555554 PP == domain 10 score: 0.0 bits; conditional E-value: 0.18 CENP-F_leu_zip 58 kaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenllee 112 ++ei++++++l le++ + r++ ++ t++ + q+ v++Le++ns+le+ e FUN_001422-T3 1034 QEEIDRISRKLATLEMKELNERERADHATRKYDQLQSLVQQLEERNSELEHKFAE 1088 6789999999999999999999999999999999999999999999999876543 PP == domain 11 score: -0.6 bits; conditional E-value: 0.29 CENP-F_leu_zip 4 kklhvlekLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrq......leldLvtlrsekeeLtkeLq 90 +l+v+ + + e++++ Lk v L+ e++ ++ e ++ + E++ +e+ +l++++ ++ e + l++ +v+l+ + ++L+ FUN_001422-T3 1115 THLSVTRRVQSLEESESKLKVEVSRLKEVAEVASHQTEAIKAQQESQDKELTSLRKQLYDMQMENDDktiigkLHHHIVALQVSEGTAVRKLE 1207 5677888888999999******************************************999877543223333999******8888888**** PP CENP-F_leu_zip 91 kkqervseLeslnsslenlleekEqekvqmkeeskaaveeLqtqlkel 138 ++ s e+l le+ + ek q+ + k e+ ++ + L++ +++l FUN_001422-T3 1208 AATQKLSRQEALVLRLEQKIDEKDQALYHAKMEARNKAKFLKKTIQDL 1255 **************************8888778877778888777766 PP == domain 12 score: 8.1 bits; conditional E-value: 0.00059 CENP-F_leu_zip 4 kklhvlekLKeserkadsLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqerv 96 k+ + +e ++ ++ L+ ++ + + e +e + +++l+ + ++ + tlk+ + ++ ++ ++++ +lr + +L++ + qe+ FUN_001422-T3 1267 KQEKFAETMRTLHDDKRTLERELKKAKNDREAAEDRLAELKLQHDGLQELMATLKDGKGA--AKVTEWHAKMGELRLQDLKLNRAVTRLQEEL 1357 566666666666667777777777777777777777777777777777777777777766..99***************************** PP CENP-F_leu_zip 97 seLeslnsslenlleekEqekvqmkeeskaa 127 + Le++ e+ ++++E+e+vqm +e++ + FUN_001422-T3 1358 KYLENVVKVHERSISDLEDENVQMAKEHEDR 1388 **************************99876 PP == domain 13 score: -8.1 bits; conditional E-value: 4 CENP-F_leu_zip 24 dkvenLerelemseenqek 42 dk e+ +rel ++ + e+ FUN_001422-T3 1404 DKLEKQQRELAEAATKFEE 1422 2222222222222222222 PP == domain 14 score: -9.6 bits; conditional E-value: 4 CENP-F_leu_zip 78 lrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeeskaaveeLqtqlkeln 139 l++e+ e ++ L+ q++vs+L+++ e+ l++ + ++ +ee+k+++e+ +++++ l+ FUN_001422-T3 1512 LTEENYETKRALKVAQATVSSLQQMLAHKEESLNKYQAMLKEAREEAKTQSEQHKVEIQLLQ 1573 45777777777777777777777777777777777777777777777777777776666554 PP == domain 15 score: -5.0 bits; conditional E-value: 4 CENP-F_leu_zip 11 kLKeserkadsLkd....kvenLerelemseenqekvileaEnskaevetlkaeieelaee..lrqleldLvtlrsekeeLtkeLqkkqervs 97 LK ++ +sL++ k e+L++ m++e +e++++++E+ k e++ l++ ++ + e +r+ + + +++ + ++ k+ +r s FUN_001422-T3 1522 ALKVAQATVSSLQQmlahKEESLNKYQAMLKEAREEAKTQSEQHKVEIQLLQDRLHLESDEtfRRKKTFHMDSVSADDSQV--PTHKQLSRLS 1612 566666555555542222668899999999999999999999999999999887654333311445555555666665555..4455556677 PP CENP-F_leu_zip 98 eLeslnsslenll 110 eLe++ + n+l FUN_001422-T3 1613 ELEEMVAEQDNAL 1625 7777766666666 PP == domain 16 score: -9.7 bits; conditional E-value: 4 CENP-F_leu_zip 45 leaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkeeskaaveeLqtq 134 +E++k+ e +++ +++++++ ++ + +L++++sek e ++ + ++ + ++ L+ ++ kE++++ + k+ ve L++q FUN_001422-T3 1638 EVMETKKEHEEDVENFKQQMTRKDEEHSNELKKITSEKMERDERIMEQSKMIEVLKDELETA------KEAAERAPSKTLKHLVERLRNQ 1721 33677788888899999999999999999999999999998888888888777666554443......4555555555555555555555 PP == domain 17 score: -5.8 bits; conditional E-value: 4 CENP-F_leu_zip 26 venLerelemseenqekvile.....aEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervs 97 +e L+ ele+++e e++ ++ +E ++++ +++ + l++ l ql++d+v++ +e+ + + ++q+ v+ FUN_001422-T3 1689 IEVLKDELETAKEAAERAPSKtlkhlVERLRNQLALKEKQQKSLSQALLQLRADMVSTAEENVQAHARRAEEQANVQ 1765 88889999999888887755411111344455554456677889999999999999999999988888888887775 PP == domain 18 score: -14.3 bits; conditional E-value: 4 CENP-F_leu_zip 10 ekLKeserkadsLkdkvenLerelems.eenqekvileaEnskaevet........lkaeieelaeelrqleldLvtlr.......sekeeLt 86 ++L e+++ sL + ++L +++ een + aE++ a v+ l++ ieel+e++++++ +L + r ek++L+ FUN_001422-T3 1720 NQLALKEKQQKSLSQALLQLRADMVSTaEENVQAHARRAEEQ-ANVQHvvdkettgLQSRIEELQERMEKFKKELRKQRdketallGEKDKLK 1811 566666677778888888888887544044433333334333.33333333455559999999999999999999999988888889****** PP CENP-F_leu_zip 87 keLqkkqerv....seLeslnsslenlleekEqe...kvqmkeeskaaveeLqtqlkelne 140 ++L kk + eL++l+ +++++le+k qe +++ + + +++e L+ + k l+e FUN_001422-T3 1812 QDLSKKDAALlkfgRELKELE-TVQEQLEKKDQElriEKNKHAQERSEIENLREKVKSLQE 1871 ******987633333444443.455667777777655445555556778888888888876 PP == domain 19 score: -2.6 bits; conditional E-value: 1.2 CENP-F_leu_zip 32 elemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekee 84 ele+++e++ek e +k++ + ++eie+l+e+ + l+ +L++ r+ + FUN_001422-T3 1830 ELETVQEQLEKKDQELRIEKNKHAQERSEIENLREKVKSLQEKLKQERKKSAD 1882 34444444444444444444444444555555555555555555554444444 PP == domain 20 score: -7.5 bits; conditional E-value: 4 CENP-F_leu_zip 13 KeserkadsLkdkvenLerelemseenqe...kvileaEnskaevet..........lkaeieelaeelrqleldLvtlrsekeeLtke.Lqk 91 K+ ++k + Lk+k + rele +++++ ++ aE+ ka + + ++ + +e ++l++ + +l +e++eL +e + FUN_001422-T3 1916 KKWQQKVETLKGKLAEKTRELEKAQKSNAmlrEALNRAEKDKAGLHSrlkssvkagvVEPSV-VTNEVVQDLKHSIFKLEEENQELRREkVLG 2007 77788888888888888899888888764111555678888888877755553333222222.235557888888888889999987653555 PP CENP-F_leu_zip 92 kqervseLeslnsslenlleekEqe..k 117 + ++++ Le +n + + + ++E + + FUN_001422-T3 2008 HDKQMEALELRNRQQMEYIGRLERDlaE 2035 6778899999998888888888888533 PP == domain 21 score: 12.5 bits; conditional E-value: 2.5e-05 CENP-F_leu_zip 21 sLkdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkq..ervseLeslnsslenlle 111 L+++ + L+++l +++e++ ++ e E++++e lka +e l+e + l+++L++ +++ + +k+L++ + v+++e++ +++++e FUN_001422-T3 2053 ELHQRNQYLQKQLLEVKEENMELRFEYEQARKENPRLKARVEDLQEYVEILKAELEASKKREKARKKNLGTGMggQSVEDMERVIAAMRRVVE 2145 58999999***************************************************999999999987542278**************** PP CENP-F_leu_zip 112 ekEqekvqmkee 123 ++ e+ q+k++ FUN_001422-T3 2146 RLQGENDQLKKS 2157 *99999888876 PP == domain 22 score: -0.7 bits; conditional E-value: 0.29 CENP-F_leu_zip 75 LvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmkees 124 ++l e+e+L k+L+k+ e+v+ L+++n le+ e++ e+ q++++ FUN_001422-T3 2203 TTKLMAENEKLLKNLKKEMEEVEKLKAANANLEQRKEDLVREMEQLQQKL 2252 44566788888888888888888888888877765544444444444433 PP == domain 23 score: 0.2 bits; conditional E-value: 0.16 CENP-F_leu_zip 23 kdkvenLerelemseenqekvileaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslen 108 ++k +Le+ele + + +++ + + + +l ++ +el+e+ le ++++s+ + L ke q+ + rv +Les ++++ + FUN_001422-T3 2275 EEKMRKLEAELEKKTNLLKDIKTYLKAAANRETELTNKQHELEEKVAILERFPTNIKSDSD-LVKEFQQTRLRVATLESEKEEILH 2359 5788899999999888888888888888777788999999999999999999999999976.6699***********999887655 PP == domain 24 score: 3.1 bits; conditional E-value: 0.02 CENP-F_leu_zip 8 vlekLKeserkadsLkdkvenLerelemse 37 ++ +LK +e + d L + +L +ele + FUN_001422-T3 2399 LRTRLKTVELERDRLSHEITKLRKELEAFD 2428 344555555555666666665555555443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2473 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 5102 (0.199726); expected 510.9 (0.02) Passed bias filter: 888 (0.0347622); expected 510.9 (0.02) Passed Vit filter: 371 (0.0145234); expected 25.5 (0.001) Passed Fwd filter: 162 (0.00634175); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 3.99u 0.50s 00:00:04.49 Elapsed: 00:00:00.72 # Mc/sec: 13983.12 // Query: FUN_001422-T4 [L=187] Description: FUN_001422 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0043 17.6 8.1 0.0043 17.6 8.1 2.2 2 ADIP Afadin- and alpha -actinin-Binding ------ inclusion threshold ------ 0.082 13.9 11.6 0.095 13.6 11.1 1.4 1 Fez1 Fez1 0.22 11.1 8.2 0.062 12.9 3.6 1.9 2 FH2 Formin Homology 2 Domain 0.22 11.8 14.0 0.11 12.8 6.5 2.6 3 CENP-H Centromere protein H (CENP-H) 0.26 11.7 5.1 0.79 10.1 3.1 2.2 2 cas_Cpf1_2nd CRISPR-associated endonuclease Cpf1 REC2 doma 0.65 10.6 14.0 0.13 12.8 7.7 2.5 2 BRE1 BRE1 E3 ubiquitin ligase 0.71 10.8 10.4 0.69 10.8 7.4 2.2 2 OVT1 Major antigen, helical domain 1 10.1 17.2 5.4 7.8 3.5 3.7 5 ABC_tran_CTD ABC transporter C-terminal domain 1.1 10.3 11.3 0.38 11.7 7.0 2.4 2 DUF4164 Domain of unknown function (DUF4164) 2 9.6 8.1 0.91 10.8 2.7 2.3 2 DUF6285 Domain of unknown function (DUF6285) 2.3 8.1 14.7 0.44 10.4 9.9 2.1 2 GAS Growth-arrest specific micro-tubule binding 2.8 8.6 13.7 0.4 11.3 7.1 2.7 3 Asd-4 Asd-4-like domain 3.3 8.2 8.0 10 6.6 5.0 2.4 2 CEP15-like Centrosomal protein 15-like 3.4 8.0 10.6 1.2 9.4 6.3 2.0 2 DUF724 Protein of unknown function (DUF724) 7.4 7.2 20.5 3.1 8.5 3.3 4.4 5 Cep57_CLD_2 Centrosome localisation domain of PPC89 8.3 6.9 16.3 39 4.7 15.9 2.1 1 UPF0242 Uncharacterised protein family (UPF0242) N-te 8.7 6.5 14.8 4.4 7.4 1.4 2.7 3 GrpE GrpE 8.9 6.0 8.4 9.3 5.9 7.1 1.8 1 DUF4407 Domain of unknown function (DUF4407) Domain annotation for each model (and alignments): >> ADIP Afadin- and alpha -actinin-Binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.3 0.25 3.6e+02 63 111 .. 50 98 .. 9 103 .. 0.58 2 ! 17.6 8.1 3e-06 0.0043 67 134 .. 114 181 .. 110 183 .. 0.95 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.25 ADIP 63 kleaeierlqseierlkeqledlerelalleakerqlekklktleqklk 111 e + ++++l+++l++ e+ + ++e++l ++++le l+ FUN_001422-T4 50 IQLFEVTKAVMKVKSLQAELAADEMHQGGGGEREQELVDEIAHLEGELQ 98 4444444555566666666666666666666666666666666665554 PP == domain 2 score: 17.6 bits; conditional E-value: 3e-06 ADIP 67 eierlqseierlkeqledlerelalleakerqlekklktleqklknekeelqrlknalqqiktqfahe 134 ei + +++ + l+++l ++e + ++k ql +l ++e+ +k++k++l r k +l +++ qf++ FUN_001422-T4 114 EIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQ 181 7889999*********************************************************9986 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 11.1 6.7e-05 0.095 31 155 .. 53 181 .. 32 184 .. 0.72 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 6.7e-05 Fez1 31 neivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqe 126 e+ + +++ l+a+l++ e + e+ ++ e+ +e+eLqr ++ + e+ + +++++ r++l++ +e++e+ ++++ ++q ++ FUN_001422-T4 53 FEVTKAVMKVKSLQAELAADEMHQGGGGEREQELVDEIAHLEGELQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLAN 148 566666678999************************************776666666666555566666666655444444444333333333222 PP Fez1 127 a....eealeslkreverlkaeLkeerqrkeeq 155 + e++ +slkr+++r k L+ +++ e+q FUN_001422-T4 149 RldaaERENKSLKRDLDRGKLDLRDLQRQFEQQ 181 233347788999999999999999999998888 PP >> FH2 Formin Homology 2 Domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.1 0.28 4e+02 272 329 .. 8 64 .. 2 76 .. 0.62 2 ? 12.9 3.6 4.3e-05 0.062 258 348 .. 88 178 .. 82 182 .. 0.91 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.28 FH2 272 kaakvnleelekevkklekglkklekelessekkeepsdkfvevlkeflkeaeeklkk 329 k+ n+e+l++++++ e + le l s ++ke + ++ +l e++ +a k+k+ FUN_001422-T4 8 KVMGANIEALREDLDAAENMYELLEMALVSPDSKEAVDANMMIQLFEVT-KAVMKVKS 64 5566778888888888888888888777777774544444444444433.33344444 PP == domain 2 score: 12.9 bits; conditional E-value: 4.3e-05 FH2 258 pelldfsseLsnvkkaakvnleelekevkklekglkklekelessekkeepsdkfvevlkeflkeaeeklkkleeelkeakelfkelveYf 348 +e+ +++ eL+ +k + e++ e++++e + +le+el+++e+++ ++++ +++l l+ ae++ k+l+ +l++ k + +l + f FUN_001422-T4 88 DEIAHLEGELQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQF 178 78999**********************************************************************9998777777766655 PP >> CENP-H Centromere protein H (CENP-H) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.1 1.1 1.5e+03 8 46 .. 25 61 .. 16 69 .. 0.54 2 ? 3.1 0.2 0.073 1e+02 128 168 .. 60 102 .. 46 103 .. 0.71 3 ? 12.8 6.5 7.8e-05 0.11 96 153 .. 113 170 .. 109 182 .. 0.88 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1.1 CENP-H 8 dqlqeleleialleaqeeeelseedaeeqleeaerelle 46 + + el le+al++ +++e+ + + ql e+ + +++ FUN_001422-T4 25 ENMYEL-LEMALVSPDSKEAVDA-NMMIQLFEVTKAVMK 61 455566.7777777776543333.333333333333333 PP == domain 2 score: 3.1 bits; conditional E-value: 0.073 CENP-H 128 elaaellelakeqkskk..eeiddpelkeqlekleaelkksrq 168 ++++l++ + ++ ++ +++++el ++++ le el+++++ FUN_001422-T4 60 MKVKSLQAELAADEMHQggGGEREQELVDEIAHLEGELQRYQK 102 4555555555545555556888888899999999999999875 PP == domain 3 score: 12.8 bits; conditional E-value: 7.8e-05 CENP-H 96 sailklsqelreleeeLtevekerlrlkrknrelaaellelakeqkskkeeiddpelk 153 +i +++++ ++le+eL+e e+ + k+kn +la++l + ++e+ks k+++d+++l+ FUN_001422-T4 113 REIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLD 170 68999*********************************************99999843 PP >> cas_Cpf1_2nd CRISPR-associated endonuclease Cpf1 REC2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.2 2.8e+02 165 194 .. 13 43 .. 6 66 .. 0.73 2 ? 10.1 3.1 0.00056 0.79 116 185 .. 95 162 .. 36 178 .. 0.66 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.2 cas_Cpf1_2nd 165 qvekiKelLDsikelqhflkpLl.kkgdeed 194 ++e ++e LD+ +++ l++ l + +++e FUN_001422-T4 13 NIEALREDLDAAENMYELLEMALvSPDSKEA 43 799999999*999999999875535554444 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00056 cas_Cpf1_2nd 116 ksiedyfkklfkedktenliekikekykkikdllene.yseekelkqdkeqvekiKelLDsikelqhflkp 185 +++ y k + e+++++i++ ++ ++le+e +++e+++ q+k++ +++ + LD+ + ++ lk FUN_001422-T4 95 GELQRYQKYD--GMGGEDFMREIRQI-ENSRNALERElNEKEEAFFQEKNKNDQLANRLDAAERENKSLKR 162 3333333323..34667777777774.4455577777789**********************999988885 PP >> BRE1 BRE1 E3 ubiquitin ligase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.3 0.56 7.9e+02 12 12 .. 76 76 .. 39 101 .. 0.51 2 ? 12.8 7.7 9.4e-05 0.13 3 73 .. 113 183 .. 111 185 .. 0.96 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.56 BRE1 12 f 12 FUN_001422-T4 76 Q 76 1 PP == domain 2 score: 12.8 bits; conditional E-value: 9.4e-05 BRE1 3 kELvklekafeelqeqlskkvkeltaleekklrleaekakadqkyfaamrskdalenelkkLnkllsKsse 73 E+ ++e+ +++l+ +l++k + + ++k +l + + a+++ ++++r+ d + +l+ L+++ +++ + FUN_001422-T4 113 REIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQVC 183 79****************************************************************99866 PP >> OVT1 Major antigen, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.92 1.3e+03 38 57 .. 14 33 .. 7 70 .. 0.64 2 ? 10.8 7.4 0.00048 0.69 3 64 .. 115 176 .. 113 183 .. 0.90 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.92 OVT1 38 lenqrarldavtseldklqt 57 +e r+ lda ++ ++ l+ FUN_001422-T4 14 IEALREDLDAAENMYELLEM 33 44444444444444444443 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00048 OVT1 3 yrdlEneYnsllrkleekdaalknleelkrkllkdlenqrarldavtseldklqteyesatk 64 +r++En n+l r+l+ek++a + ++ +++l++ l+ ++ ++ +ld+ + ++ +++ FUN_001422-T4 115 IRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQR 176 79************************************************998887776665 PP >> ABC_tran_CTD ABC transporter C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.054 76 49 68 .. 13 32 .. 9 48 .. 0.81 2 ? 6.0 0.7 0.014 19 23 59 .. 61 99 .. 53 104 .. 0.81 3 ? 7.8 3.5 0.0038 5.4 11 63 .. 84 135 .. 80 137 .. 0.89 4 ? 5.8 6.0 0.015 22 15 56 .. 113 156 .. 108 162 .. 0.84 5 ? 4.0 0.6 0.058 83 4 32 .. 137 165 .. 135 180 .. 0.82 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.054 ABC_tran_CTD 49 eleeleeeleelyerWeeLe 68 +e+l+e+l++++ +e Le FUN_001422-T4 13 NIEALREDLDAAENMYELLE 32 67888888888888888776 PP == domain 2 score: 6.0 bits; conditional E-value: 0.014 ABC_tran_CTD 23 eiaeleaqladpelysdy..eklaelsaeleeleeelee 59 ++++l+a+la+ e+ + e+ +el +e++ le el+ FUN_001422-T4 61 KVKSLQAELAADEMHQGGggEREQELVDEIAHLEGELQR 99 677899999999988666688899999999999999875 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0038 ABC_tran_CTD 11 eeleaeIekLEeeiaeleaqladpelysdy.eklaelsaeleeleeeleelyer 63 +el +eI+ LE e+++ ++ + +d+ ++ ++ + ++le+el+e++e FUN_001422-T4 84 QELVDEIAHLEGELQRYQKYDGMGG--EDFmREIRQIENSRNALERELNEKEEA 135 57889*************9766666..99999*******************995 PP == domain 4 score: 5.8 bits; conditional E-value: 0.015 ABC_tran_CTD 15 aeIekLEeeiaeleaqladpe..lysdyeklaelsaeleeleee 56 +eI ++E+ +le +l++ e ++++ k ++l ++l+++e+e FUN_001422-T4 113 REIRQIENSRNALERELNEKEeaFFQEKNKNDQLANRLDAAERE 156 799999***********97542288999999********99987 PP == domain 5 score: 4.0 bits; conditional E-value: 0.058 ABC_tran_CTD 4 ykeqreleeleaeIekLEeeiaeleaqla 32 ++e+ + ++l +++++E e ++l l FUN_001422-T4 137 FQEKNKNDQLANRLDAAERENKSLKRDLD 165 78999999999999999999999988776 PP >> DUF4164 Domain of unknown function (DUF4164) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 3.3 4.6e+03 49 63 .. 15 29 .. 8 37 .. 0.59 2 ? 11.7 7.0 0.00027 0.38 10 82 .. 83 156 .. 79 166 .. 0.91 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 3.3 DUF4164 49 srLaqeLdqaearan 63 + L ++Ld+ae+ + FUN_001422-T4 15 EALREDLDAAENMYE 29 445666666665544 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00027 DUF4164 10 lkrLeaaldrLesavdrrleaerae.aeleaeveaLqadrsrLaqeLdqaearaneleeanrEisrrLdsaiet 82 +++L + +Le ++r + +++ +++ +e++++++ r+ L+ eL ++e + ++ n+ ++rLd+a + FUN_001422-T4 83 EQELVDEIAHLEGELQRYQKYDGMGgEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERE 156 6888889999************998789******************************************9765 PP >> DUF6285 Domain of unknown function (DUF6285) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.2 0.42 5.9e+02 46 74 .. 59 88 .. 17 98 .. 0.65 2 ? 10.8 2.7 0.00064 0.91 15 69 .. 119 173 .. 111 186 .. 0.87 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.42 DUF6285 46 dgdleelnaeLaa.airaGeldldtpalla 74 ++++l+aeLaa ++ +G +++++l++ FUN_001422-T4 59 VMKVKSLQAELAAdEMHQGGGGEREQELVD 88 336777777776425666666666666655 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00064 DUF6285 15 aNalaiveRelelgpaaaaaerarlaallgedgdleelnaeLaaairaGeldldt 69 N + +eRel+ +++a +e+++ +l + + e+ n+ L + + +G+ldl++ FUN_001422-T4 119 ENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRD 173 6788899**********999999999999999999*****************985 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.7 0.56 8e+02 93 93 .. 51 51 .. 9 102 .. 0.53 2 ? 10.4 9.9 0.00031 0.44 9 89 .. 96 176 .. 89 183 .. 0.86 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.56 GAS 93 r 93 + FUN_001422-T4 51 Q 51 1 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00031 GAS 9 afeeiknYYnditrnnLelikslKeeiaelkkkeeenekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslkn 89 +++ +++Y ++ + i++ ++ ++l+++ +e+e + + +++n +l+ L +ae+e++ Lk++l++ + d +l++ FUN_001422-T4 96 ELQRYQKYDGMGGEDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQR 176 5677777777777788899999***********************************************998888777776 PP >> Asd-4 Asd-4-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 2.3 3.3e+03 51 70 .. 13 32 .. 7 41 .. 0.72 2 ? 0.0 0.1 0.93 1.3e+03 43 59 .. 81 97 .. 54 106 .. 0.57 3 ? 11.3 7.1 0.00029 0.4 29 76 .. 113 167 .. 109 171 .. 0.72 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 2.3 Asd-4 51 eeaqLraeleeaqrreeelk 70 + + Lr++l++a++ e l+ FUN_001422-T4 13 NIEALREDLDAAENMYELLE 32 55678888888887666555 PP == domain 2 score: 0.0 bits; conditional E-value: 0.93 Asd-4 43 rseeaareeeaqLrael 59 ++e++ +e a+L+ el FUN_001422-T4 81 EREQELVDEIAHLEGEL 97 23334444444555544 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00029 Asd-4 29 gRvseLEqseaaarr....see...aareeeaqLraeleeaqrreeelkrrldel 76 + ++++E+s +a r +ee +++++++qL ++l++a+r++++lkr ld+ FUN_001422-T4 113 REIRQIENSRNALERelneKEEaffQEKNKNDQLANRLDAAERENKSLKRDLDRG 167 56889998887764422222223334567899********************986 PP >> CEP15-like Centrosomal protein 15-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.19 2.6e+02 51 70 .. 80 99 .. 47 104 .. 0.80 2 ? 6.6 5.0 0.0071 10 26 70 .. 129 173 .. 111 186 .. 0.78 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.19 CEP15-like 51 kkRNakllkdlealekslqk 70 +R ++l++++ +le +lq+ FUN_001422-T4 80 GEREQELVDEIAHLEGELQR 99 5899************9996 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0071 CEP15-like 26 LqqmenkledqkkkkksqleaakaAkkRNakllkdlealekslqk 70 L++ e+ + ++k+k + ++ +aA++ N++l +dl++ + l+ FUN_001422-T4 129 LNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRD 173 6777888889999999999*****************998766665 PP >> DUF724 Protein of unknown function (DUF724) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.1 0.88 1.3e+03 36 62 .. 37 63 .. 26 75 .. 0.72 2 ? 9.4 6.3 0.00088 1.2 112 184 .. 109 181 .. 84 183 .. 0.89 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.88 DUF724 36 keelREgsAlglmvtFagllekvkklq 62 +++++E + +m++ +++ + v+k++ FUN_001422-T4 37 SPDSKEAVDANMMIQLFEVTKAVMKVK 63 567778888888888877777666654 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00088 DUF724 112 kklekkiaeeesekrkleeeidelekkilelerqeallkekkeakdkeiarlkseaekleqeiedveleFeat 184 +++ ++i++ e++++ le e++e e++ + +++++ l ++ +a+++e ++lk + ++ + +++d++++Fe+ FUN_001422-T4 109 EDFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQ 181 67789999999*************************9*********************************975 PP >> Cep57_CLD_2 Centrosome localisation domain of PPC89 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.014 19 3 23 .. 12 32 .. 10 37 .. 0.83 2 ? -2.2 0.0 4.6 6.6e+03 54 63 .. 62 71 .. 56 76 .. 0.55 3 ? 2.0 0.1 0.22 3.1e+02 46 64 .. 82 100 .. 77 102 .. 0.85 4 ? 0.5 1.2 0.67 9.4e+02 45 66 .. 113 134 .. 110 135 .. 0.83 5 ? 8.5 3.3 0.0022 3.1 9 34 .. 140 165 .. 140 180 .. 0.76 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.014 Cep57_CLD_2 3 aenlaLqnrLdsltrklevhe 23 a ++aL+++Ld ++ +e e FUN_001422-T4 12 ANIEALREDLDAAENMYELLE 32 7899*********99888776 PP == domain 2 score: -2.2 bits; conditional E-value: 4.6 Cep57_CLD_2 54 nealrkElke 63 + +l+ El FUN_001422-T4 62 VKSLQAELAA 71 3344444443 PP == domain 3 score: 2.0 bits; conditional E-value: 0.22 Cep57_CLD_2 46 eiqeLkaenealrkElkeq 64 + qeL +e +l++El+ + FUN_001422-T4 82 REQELVDEIAHLEGELQRY 100 569999*********9976 PP == domain 4 score: 0.5 bits; conditional E-value: 0.67 Cep57_CLD_2 45 leiqeLkaenealrkElkeqra 66 +ei++ + + al++El e+++ FUN_001422-T4 113 REIRQIENSRNALERELNEKEE 134 6888999999999999999875 PP == domain 5 score: 8.5 bits; conditional E-value: 0.0022 Cep57_CLD_2 9 qnrLdsltrklevheselkrLrrERD 34 +n++d+l +l+++e e+k+L r+ D FUN_001422-T4 140 KNKNDQLANRLDAAERENKSLKRDLD 165 58888888888888888888888655 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 15.9 0.028 39 91 160 .. 114 179 .. 54 185 .. 0.77 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.028 UPF0242 91 eleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfaefkleseeqlkekqlllneyqetie 160 e+++ ++ + le+el++kee+ + k++++ql +l++++++++ +k++++ +l l +q ++e FUN_001422-T4 114 EIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRLDAAERENKSLKRDLDR----GKLDLRDLQRQFE 179 55566666789*******************************99999998764....3333334444443 PP >> GrpE GrpE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 1.4 2e+03 79 79 .. 32 32 .. 10 70 .. 0.52 2 ? 7.4 1.4 0.0031 4.4 5 58 .. 82 135 .. 73 139 .. 0.81 3 ? 4.8 5.8 0.02 28 6 51 .. 136 181 .. 131 184 .. 0.90 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.4 GrpE 79 n 79 + FUN_001422-T4 32 E 32 1 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0031 GrpE 5 eeeeekekieeleeeieelekkikel.kekllralaefenlrkrtekekeeakkf 58 +e+e+ ++i+ le e+++ +k ++ + e ++r+ ++en r+ +e+e++e+++ FUN_001422-T4 82 REQELVDEIAHLEGELQRYQK-YDGMgGEDFMREIRQIENSRNALERELNEKEEA 135 577888888888888888776.5555589999****************9998775 PP == domain 3 score: 4.8 bits; conditional E-value: 0.02 GrpE 6 eeeekekieeleeeieelekkikelkekllralaefenlrkrteke 51 +ek+k+++l ++++++e+++k+lk l r + ++ l++++e++ FUN_001422-T4 136 FFQEKNKNDQLANRLDAAERENKSLKRDLDRGKLDLRDLQRQFEQQ 181 567999*********************************9999886 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 7.1 0.0065 9.3 158 250 .. 63 154 .. 10 162 .. 0.78 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0065 DUF4407 158 delqkearcelegtkgtgttgvpGkGpeakekeeeldaaqaelaalqak.......ntaklealraeiarleaekaaeeaaseaaiaaddGllaRl 246 + lq+e++ + G G +e +e++ ++ el+ +q++ ++ + ++ + le+e +++e+a+ ++ +++d l+ Rl FUN_001422-T4 63 KSLQAELA----ADEM----HQGGGGEREQELVDEIAHLEGELQRYQKYdgmggedFMREIRQIENSRNALERELNEKEEAFFQEKNKNDQLANRL 150 44444333....2221....1236789999999999999999999999999999987777777777777888888888888888899999999999 PP DUF4407 247 eALd 250 +A + FUN_001422-T4 151 DAAE 154 8865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2008 (0.0786064); expected 510.9 (0.02) Passed bias filter: 752 (0.0294382); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 23 (0.000900372); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 1903.95 // Query: FUN_001423-T1 [L=1571] Description: FUN_001423 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.9e-101 331.0 66.0 9.6e-12 45.6 0.1 13.4 13 EF-hand_7 EF-hand domain pair 3.7e-85 282.2 22.9 9.7e-09 36.5 0.0 13.1 13 EF-hand_11 EF-hand domain 1.2e-82 266.0 44.3 9.2e-07 28.5 0.3 20.5 20 EF-hand_1 EF hand domain 1.6e-74 238.9 64.1 5.4e-06 26.2 0.2 20.0 20 EF-hand_6 EF-hand domain 3.4e-57 187.9 33.7 1.5e-06 27.9 0.1 15.4 15 EF-hand_5 EF hand 2.2e-22 79.0 38.0 0.48 10.7 0.1 17.5 18 EF-hand_8 EF-hand domain pair 3.6e-20 72.0 11.5 0.085 13.2 0.0 12.2 13 EF-hand_EFHB_C EFHB C-terminal EF-hand domain 7e-19 69.0 36.4 0.02 15.6 0.1 11.9 12 AIF-1 Allograft inflammatory factor 1 2.4e-16 60.0 7.7 0.0012 19.3 0.1 8.2 9 EH EH domain 2.7e-16 60.5 33.0 1.2 10.1 0.1 14.4 14 EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domai 2.4e-12 47.4 6.6 0.2 12.4 0.0 9.7 10 Dockerin_1 Dockerin type I domain 2.3e-10 40.9 10.0 1 10.0 0.1 9.2 9 DUF5580_M Family of unknown function (DUF5580) middle 4.8e-08 33.8 4.9 0.34 11.9 0.0 9.0 8 EF-hand_9 EF-hand domain 8.1e-07 29.1 3.7 5.1 7.3 0.0 7.9 10 EF_EFCAB10_C EFCAB10, C-terminal EF-hand 9e-07 29.7 27.0 0.078 13.8 0.0 10.2 10 SPARC_Ca_bdg Secreted protein acidic and rich in cysteine 2.3e-06 28.1 6.6 2.9 8.6 0.1 8.7 9 SF3A3 Pre-mRNA-splicing factor SF3A3, of SF3a comp 5.1e-06 26.9 0.0 4.5 7.9 0.0 5.3 3 DUF5580 Family of unknown function (DUF5580) N-termi 1.7e-05 25.1 0.1 15 6.0 0.0 6.4 6 GPHH Voltage-dependent L-type calcium channel, IQ 0.00013 22.5 7.5 17 6.1 0.0 8.0 7 EF-hand_STIM1 Stromal interaction molecule 1-like, EF-hand 0.0079 16.7 14.4 23 5.6 0.0 8.2 9 EFhand_Ca_insen Ca2+ insensitive EF hand ------ inclusion threshold ------ 0.015 16.0 8.7 3.6 8.3 0.1 5.4 5 BCNT Bucentaur or craniofacial development 0.027 15.0 2.5 14 6.3 0.0 4.7 3 EF-hand_10 EF hand 0.03 15.2 0.4 0.26 12.2 0.4 2.7 1 PfUIS3 Plasmodium falciparum UIS3 membrane protein 0.039 14.6 0.3 33 5.2 0.0 3.9 3 RPN13_C UCH-binding domain 0.04 13.6 0.4 0.82 9.3 0.0 3.3 3 Wap1 Wap1 domain 0.12 12.8 1.6 0.46 10.8 0.2 2.8 2 W02B3_4_N W02B3.4-like, N-terminal domain 0.13 13.1 0.0 1e+02 3.7 0.0 4.0 4 HycA_repressor Transcriptional repressor of hyc and hyp ope 0.2 12.5 3.7 70 4.4 0.1 5.2 3 HSCB_C HSCB C-terminal oligomerisation domain 0.42 11.4 12.8 2.1 9.1 0.2 5.4 5 ORF6N ORF6N domain 0.42 11.0 18.5 7.9 6.9 0.0 8.9 10 Caleosin Caleosin related protein 0.47 11.3 2.2 6.2 7.7 0.0 4.1 2 EF-hand_14 EF-hand domain 1.6 9.4 7.6 19 5.9 0.0 5.4 5 DUF5580_C Family of unknown function (DUF5580) C-termi 1.7 9.7 3.2 57 4.8 0.1 4.3 2 HEF_HK HEF_HK domain 2.6 8.6 7.4 39 4.8 0.1 5.3 6 DUF7874 Family of unknown function (DUF7874) 3.7 7.9 5.4 1.7e+02 2.5 0.0 5.9 6 COR-A C-terminal of Roc, COR-A domain 7 7.1 10.6 89 3.5 0.0 6.9 5 SAPC2_N SAPC2 EF-hand like N-terminal domain Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.6 0.1 1.4e-14 9.6e-12 3 66 .. 118 179 .. 116 180 .. 0.95 2 ! 22.4 0.6 2.3e-07 0.00016 4 64 .. 227 286 .. 224 288 .. 0.89 3 ! 20.1 0.1 1.2e-06 0.00088 5 64 .. 350 407 .. 348 410 .. 0.88 4 ! 30.5 1.4 6.6e-10 4.7e-07 2 66 .. 459 521 .. 458 522 .. 0.90 5 ! 33.4 0.1 8.4e-11 6e-08 11 63 .. 575 625 .. 567 628 .. 0.91 6 ! 27.4 0.3 6.5e-09 4.6e-06 2 66 .. 695 756 .. 694 757 .. 0.92 7 ! 33.0 2.2 1.1e-10 8.1e-08 1 66 [. 803 866 .. 803 867 .. 0.95 8 ! 41.5 0.5 2.5e-13 1.8e-10 2 64 .. 912 972 .. 911 974 .. 0.97 9 ! 28.7 1.1 2.5e-09 1.8e-06 2 67 .] 1041 1104 .. 1040 1104 .. 0.94 10 ! 31.1 0.2 4.4e-10 3.1e-07 2 66 .. 1152 1214 .. 1151 1215 .. 0.92 11 ! 29.8 0.0 1.1e-09 8.1e-07 2 66 .. 1268 1330 .. 1267 1331 .. 0.95 12 ! 14.4 0.1 7.2e-05 0.051 3 65 .. 1398 1458 .. 1397 1460 .. 0.93 13 ! 13.3 0.1 0.00016 0.11 3 57 .. 1508 1560 .. 1507 1566 .. 0.89 Alignments for each domain: == domain 1 score: 45.6 bits; conditional E-value: 1.4e-14 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 +l++aF+++Ds+++ +++++e+k++l+ + +pl+d+++e+l++++ +++dG++s+ EFl+ y FUN_001423-T1 118 ELRQAFQTFDSEKTHTITQSEFKRALE--SFCIPLTDDQFEQLIRKVGTNRDGTVSYLEFLDRY 179 79*************************..89999**************************9876 PP == domain 2 score: 22.4 bits; conditional E-value: 2.3e-07 EF-hand_7 4 lkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdG.risfeEFle 64 ++a +l+D ++dG++ + el++++++ + l+de++++l+ + D +++G ++++ +Fl+ FUN_001423-T1 227 VMKALRLFDYNRDGKIQRHELRRVIEN--FCFRLTDEQFDKLWSKYDMTRNGqTLEYMDFLK 286 57899*********************5..5555899***************87899999987 PP == domain 3 score: 20.1 bits; conditional E-value: 1.2e-06 EF-hand_7 5 keaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFle 64 +aF ++D+ gdG+++ +elk++l ++p+sd+ + el+ +++i + Fle FUN_001423-T1 350 SRAFVAFDTRGDGFVTLDELKRVLF--NFAFPMSDKLFVELMSRCGIRANHKIPYVQFLE 407 589*********************9..99******9988888888999999999988887 PP == domain 4 score: 30.5 bits; conditional E-value: 6.6e-10 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 + k+aF +D ++dG++++ +++++l+ + + +s++++ el+ ++D+ + G++s+ +Fl+ + FUN_001423-T1 459 SSVKQAFLVFDDNKDGRVTKRDFRRVLE--SFCFRMSHQQFHELMAKIDPYNKGYVSYLDFLDRF 521 6689************************..5555578899*********************9865 PP == domain 5 score: 33.4 bits; conditional E-value: 8.4e-11 EF-hand_7 11 lDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFl 63 D+d+dG+++++el++ll+ + p+sd++++ ++ D + dG+i+f+EFl FUN_001423-T1 575 VDTDRDGSISRSELRQLLE--RFCLPVSDDHFDLMWSRCDENADGSIDFQEFL 625 59*****************..6666778999*********************8 PP == domain 6 score: 27.4 bits; conditional E-value: 6.5e-09 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 ++l++ F ++Ds+gdG+++++e++ ++ + ++g ++d++++ l + ++ G++s+ EFl+ + FUN_001423-T1 695 TDLRKTFVKFDSNGDGKISRKEFR-MVMN-SLGLYMTDDQFRILSARLGFHR-GKLSYMEFLNNF 756 5899********************.6666.******************9999.9*******9865 PP == domain 7 score: 33.0 bits; conditional E-value: 1.1e-10 EF-hand_7 1 eeklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 +++l+ aF+++D d++G++++ e++++l + + lsdee+++l+ +D k r+++ EFl+ + FUN_001423-T1 803 FQDLRAAFQKIDYDRNGFVTRPEFRRILD--SFMIMLSDEEFDKLMARLDIQKGARLNYREFLKRF 866 689**************************..889999**************************987 PP == domain 8 score: 41.5 bits; conditional E-value: 2.5e-13 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFle 64 e+l +aF ++D+dg+G ++++el+k+l ++++pl +ee+++l+++ D+d++G+++ +EFl+ FUN_001423-T1 912 EDLAKAFLAFDHDGNGIVTKKELRKVLY--KYQIPLNKEEFKKLWDKYDTDRNGYVDHQEFLA 972 6899************************..9******************************96 PP == domain 9 score: 28.7 bits; conditional E-value: 2.5e-09 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlelys 67 e l++aF++ D ++dGy++++el+k+l + + l+d +++ l++ l++ +++s+e Fl +++ FUN_001423-T1 1041 ESLRKAFETVDANRDGYISRQELQKVLF--DFHYFLDDVQLNILLDRCGLSHKNKLSYEKFLSAFQ 1104 689*************************..888889999***********************9985 PP == domain 10 score: 31.1 bits; conditional E-value: 4.4e-10 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 e +++aF ++D+ g+G +++e+l+++++ + +sd+++++l+k++ ++ G +s+e+F + + FUN_001423-T1 1152 ETIRRAFAAFDRYGNGLISKEDLHQIIN--AFCFIMSDKQFQALLKKIKISEGGFVSYEDFFNSF 1214 579*********************9999..77777999***********************8765 PP == domain 11 score: 29.8 bits; conditional E-value: 1.1e-09 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 + l +aF D ++G++ + l+++l+ e ++ ++ ++++++++ +D++ dG++++ +Fl+ + FUN_001423-T1 1268 YSLAKAFTDGDPRHTGTVGPSALHEILN--EHAFRMTSDQFNHIWNLLDKNADGKVDYRDFLKRF 1330 568899**********************..********************************987 PP == domain 12 score: 14.4 bits; conditional E-value: 7.2e-05 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlel 65 ++++ F+ Ds++ G ++ e+l+++l + +++ls+ e+ +l+++ + G i + +F++ FUN_001423-T1 1398 HIQKSFRNTDSENKGVVNFEQLRDILL--KHDIELSPREFLSLWRKHSNEGKGGIVYKDFMRH 1458 799************************..9999999999*******999999********976 PP == domain 13 score: 13.3 bits; conditional E-value: 0.00016 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGri 57 ++++aF++lD+ g+G+ + ++++++r + +++ls+e+ +lf + D+ G++ FUN_001423-T1 1508 AMRRAFRALDKCGSGTCSLLQFREMMR--KFKIDLSEEDYFHLFSYYDKLLTGKV 1560 689************************..888889999999*****999776665 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.1 0.1 5.7e-09 4e-06 9 83 .. 106 180 .. 101 187 .. 0.89 2 ! 35.4 0.0 3.1e-11 2.2e-08 5 96 .. 210 301 .. 206 310 .. 0.87 3 ! 8.8 0.0 0.0058 4.1 8 87 .. 335 414 .. 330 421 .. 0.90 4 ! 22.3 0.0 3.7e-07 0.00027 5 88 .. 444 527 .. 441 543 .. 0.86 5 ! 31.5 0.0 5.1e-10 3.6e-07 11 86 .. 557 632 .. 551 641 .. 0.93 6 ! 18.6 0.1 5.1e-06 0.0036 22 85 .. 697 759 .. 680 766 .. 0.86 7 ! 28.7 0.1 3.7e-09 2.6e-06 10 84 .. 794 868 .. 787 877 .. 0.87 8 ! 15.6 0.0 4.6e-05 0.032 22 87 .. 914 979 .. 899 992 .. 0.85 9 ! 17.5 0.0 1.2e-05 0.0082 10 90 .. 1031 1111 .. 1025 1123 .. 0.89 10 ! 21.8 0.0 5e-07 0.00036 11 84 .. 1143 1216 .. 1135 1222 .. 0.89 11 ! 36.5 0.0 1.4e-11 9.7e-09 5 85 .. 1253 1333 .. 1250 1346 .. 0.93 12 ! 15.0 0.0 6.6e-05 0.047 6 85 .. 1383 1462 .. 1380 1471 .. 0.90 13 ? 3.8 0.0 0.21 1.5e+02 7 79 .. 1494 1566 .. 1490 1570 .. 0.87 Alignments for each domain: == domain 1 score: 28.1 bits; conditional E-value: 5.7e-09 EF-hand_11 9 arlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflskls 83 +r++ + + q f+ fd+ k+ t+++ ef+ + ltd+qf++l ++ n g + y +fl ++ FUN_001423-T1 106 SRMREKIRVNSAELRQAFQTFDSEKTHTITQSEFKRALESFCIPLTDDQFEQLIRKVGTNRDGTVSYLEFLDRYH 180 677777777777899*******************9999999999***************************9986 PP == domain 2 score: 35.4 bits; conditional E-value: 3.1e-11 EF-hand_11 5 rdilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgr.lkyqdflsklsiervaatpmaagd 96 di +l+k + + +++++ + fd + + r+e+r + + ltdeqfd+lws+ + +g+ l y dfl +l ++ + + +g+ FUN_001423-T1 210 DDIEDQLRKKMGGQLQSVMKALRLFDYNRDGKIQRHELRRVIENFCFRLTDEQFDKLWSKYDMTRNGQtLEYMDFLKRLGVK-AKSDINKTGE 301 68889999999*************************************************9999998659*********998.5555555554 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0058 EF-hand_11 8 larlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsierv 87 +l+k + + i + f fdt v+ +e++ + ++d+ f l s + a+ ++ y +fl k+ + + FUN_001423-T1 335 EQKLRKRMLENHGNISRAFVAFDTRGDGFVTLDELKRVLFNFAFPMSDKLFVELMSRCGIRANHKIPYVQFLEKFEAPVT 414 56788888888889************************9999999*****************************987654 PP == domain 4 score: 22.3 bits; conditional E-value: 3.7e-07 EF-hand_11 5 rdilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsierva 88 di l+ + + ++ q f fd k v++ +fr + + ++ +qf l +++ kg + y dfl ++ + FUN_001423-T1 444 EDIWKLLHDRILNSFSSVKQAFLVFDDNKDGRVTKRDFRRVLESFCFRMSHQQFHELMAKIDPYNKGYVSYLDFLDRFEQRETE 527 57888899999999************************************************9***************876543 PP == domain 5 score: 31.5 bits; conditional E-value: 5.1e-10 EF-hand_11 11 lqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsier 86 lq ++ ++ai+ + dt + ++sr e+r + +r ++d+ fd +ws na g + +q+fl kl ++ FUN_001423-T1 557 LQSKITDNWKAIASAYLGVDTDRDGSISRSELRQLLERFCLPVSDDHFDLMWSRCDENADGSIDFQEFLGKLGVDI 632 57789999****************************************************************9875 PP == domain 6 score: 18.6 bits; conditional E-value: 5.1e-06 EF-hand_11 22 ivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsie 85 + + f +fd+ +sr+efr + + +td+qf l + l +g+l y +fl ++ FUN_001423-T1 697 LRKTFVKFDSNGDGKISRKEFRMVMNSLGLYMTDDQFRILSARLGF-HRGKLSYMEFLNNFQDR 759 5678999******************************999888886.69*********999765 PP == domain 7 score: 28.7 bits; conditional E-value: 3.7e-09 EF-hand_11 10 rlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsi 84 +++ + ++ + f+++d + v+r efr i + + +l+de+fd+l + l ++ rl+y++fl ++ FUN_001423-T1 794 KMKTKLRENFQDLRAAFQKIDYDRNGFVTRPEFRRILDSFMIMLSDEEFDKLMARLDIQKGARLNYREFLKRFQH 868 55666666777778889999999999**********************************************975 PP == domain 8 score: 15.6 bits; conditional E-value: 4.6e-05 EF-hand_11 22 ivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsierv 87 +++ f fd v+++e+r + + l e+f +lw++ + +g + +q+fl++l e FUN_001423-T1 914 LAKAFLAFDHDGNGIVTKKELRKVLYKYQIPLNKEEFKKLWDKYDTDRNGYVDHQEFLARLGGEMK 979 5677889999999999*******998877779*****************************99944 PP == domain 9 score: 17.5 bits; conditional E-value: 1.2e-05 EF-hand_11 10 rlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsiervaat 90 rl+ y ++ + fe d+ + +sr+e++ + l d q++ l + + k +l y+ fls + r a FUN_001423-T1 1031 RLRDRFRDGYESLRKAFETVDANRDGYISRQELQKVLFDFHYFLDDVQLNILLDRCGLSHKNKLSYEKFLSAFQDHRLAGY 1111 6666777789999*************************999********************************99988765 PP == domain 10 score: 21.8 bits; conditional E-value: 5e-07 EF-hand_11 11 lqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsi 84 l+ ++ +i + f fd +s+e++ i + i++d+qf+ l +++ + g + y+df+ + FUN_001423-T1 1143 LRGKISENPETIRRAFAAFDRYGNGLISKEDLHQIINAFCFIMSDKQFQALLKKIKISEGGFVSYEDFFNSFQK 1216 5556667778999*******************************************************998865 PP == domain 11 score: 36.5 bits; conditional E-value: 1.4e-11 EF-hand_11 5 rdilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsie 85 d+ +++ v ++++++++ f + d ++ tv + i + + +t +qf+ +w+ l na g++ y+dfl ++s+ FUN_001423-T1 1253 ADVEKKVREVVVAKFYSLAKAFTDGDPRHTGTVGPSALHEILNEHAFRMTSDQFNHIWNLLDKNADGKVDYRDFLKRFSTR 1333 68888999**********************************************************************986 PP == domain 12 score: 15.0 bits; conditional E-value: 6.6e-05 EF-hand_11 6 dilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsie 85 d+ +++ ++ ++ i + f n d+ + v e++r i ++ l+ +f lw + + kg + y+df+ ++ + FUN_001423-T1 1383 DVERKIKDLICRRWQHIQKSFRNTDSENKGVVNFEQLRDILLKHDIELSPREFLSLWRKHSNEGKGGIVYKDFMRHFVLN 1462 5666778888999999****************************999***************************998765 PP == domain 13 score: 3.8 bits; conditional E-value: 0.21 EF-hand_11 7 ilarlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdfl 79 ++a l+ v ++a+ + f +d s t s +fr + + l++e++ l+s g++ y fl FUN_001423-T1 1494 LMAALRAPVRRDWKAMRRAFRALDKCGSGTCSLLQFREMMRKFKIDLSEEDYFHLFSYYDKLLTGKVCYISFL 1566 678888999999**************************97665555999999999999999999999998887 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 6.5e-06 0.0046 1 28 [. 118 145 .. 118 146 .. 0.94 2 ! 9.7 0.0 0.0013 0.94 2 24 .. 155 177 .. 154 181 .. 0.91 3 ! 17.1 0.0 5.5e-06 0.0039 3 27 .. 228 252 .. 226 254 .. 0.90 4 ? 0.0 0.0 1.6 1.1e+03 2 16 .. 263 277 .. 262 277 .. 0.91 5 ! 18.3 0.1 2.3e-06 0.0016 3 26 .. 350 373 .. 348 376 .. 0.90 6 ! 18.4 0.2 2.2e-06 0.0016 2 28 .. 461 487 .. 460 488 .. 0.93 7 ? 1.8 0.0 0.42 3e+02 2 24 .. 497 519 .. 496 523 .. 0.88 8 ! 14.9 0.0 2.8e-05 0.02 9 28 .. 575 594 .. 571 595 .. 0.92 9 ! 14.1 0.2 5.2e-05 0.037 2 23 .. 604 625 .. 603 626 .. 0.92 10 ! 28.5 0.3 1.3e-09 9.2e-07 1 29 [] 696 724 .. 696 724 .. 0.94 11 ! 21.1 0.0 2.9e-07 0.0002 1 27 [. 805 831 .. 805 833 .. 0.92 12 ? -0.2 0.0 1.9 1.3e+03 1 27 [. 841 867 .. 841 869 .. 0.86 13 ! 17.9 0.0 3.1e-06 0.0022 2 28 .. 914 940 .. 913 941 .. 0.91 14 ! 22.7 0.1 9.3e-08 6.6e-05 1 24 [. 949 972 .. 949 975 .. 0.93 15 ! 23.8 0.0 4.1e-08 2.9e-05 2 26 .. 1043 1067 .. 1042 1070 .. 0.93 16 ! 11.0 0.0 0.00048 0.34 2 28 .. 1154 1180 .. 1153 1181 .. 0.92 17 ? -1.9 0.1 6.6 4.7e+03 15 24 .. 1203 1212 .. 1203 1216 .. 0.82 18 ! 14.1 0.1 5e-05 0.035 2 25 .. 1306 1329 .. 1305 1332 .. 0.87 19 ! 10.2 0.0 0.00091 0.64 2 27 .. 1399 1424 .. 1398 1426 .. 0.91 20 ! 16.9 0.0 6.2e-06 0.0044 2 29 .] 1509 1536 .. 1508 1536 .. 0.94 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 6.5e-06 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkk 28 el+++F+ fD + +I+ +Efk++l + FUN_001423-T1 118 ELRQAFQTFDSEKTHTITQSEFKRALES 145 79***********************986 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0013 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfke 24 +++++r++ +++dG++++ Ef++ FUN_001423-T1 155 FEQLIRKVGTNRDGTVSYLEFLD 177 7899*****************86 PP == domain 3 score: 17.1 bits; conditional E-value: 5.5e-06 EF-hand_1 3 keiFrefDkDgdGkIdfeEfkellk 27 ++ r+fD ++dGkI + E+++++ FUN_001423-T1 228 MKALRLFDYNRDGKIQRHELRRVIE 252 7899*****************9986 PP == domain 4 score: 0.0 bits; conditional E-value: 1.6 EF-hand_1 2 lkeiFrefDkDgdGk 16 ++++++++D ++G+ FUN_001423-T1 263 FDKLWSKYDMTRNGQ 277 89**********996 PP == domain 5 score: 18.3 bits; conditional E-value: 2.3e-06 EF-hand_1 3 keiFrefDkDgdGkIdfeEfkell 26 ++F fD+ gdG+++++E+k++l FUN_001423-T1 350 SRAFVAFDTRGDGFVTLDELKRVL 373 689******************997 PP == domain 6 score: 18.4 bits; conditional E-value: 2.2e-06 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkk 28 +k++F +fD ++dG++++ +f+++l + FUN_001423-T1 461 VKQAFLVFDDNKDGRVTKRDFRRVLES 487 799********************9986 PP == domain 7 score: 1.8 bits; conditional E-value: 0.42 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfke 24 + e+++++D + G++++ +f++ FUN_001423-T1 497 FHELMAKIDPYNKGYVSYLDFLD 519 789999************99987 PP == domain 8 score: 14.9 bits; conditional E-value: 2.8e-05 EF-hand_1 9 fDkDgdGkIdfeEfkellkk 28 +D+D+dG I+++E+++ll + FUN_001423-T1 575 VDTDRDGSISRSELRQLLER 594 7****************986 PP == domain 9 score: 14.1 bits; conditional E-value: 5.2e-05 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfk 23 ++ +++ D + dG Idf+Ef+ FUN_001423-T1 604 FDLMWSRCDENADGSIDFQEFL 625 7889*****************6 PP == domain 10 score: 28.5 bits; conditional E-value: 1.3e-09 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkkl 29 +l++ F +fD +gdGkI+++Ef+ ++++l FUN_001423-T1 696 DLRKTFVKFDSNGDGKISRKEFRMVMNSL 724 689***********************875 PP == domain 11 score: 21.1 bits; conditional E-value: 2.9e-07 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellk 27 +l+ +F+++D D++G++++ Ef+++l FUN_001423-T1 805 DLRAAFQKIDYDRNGFVTRPEFRRILD 831 5899********************986 PP == domain 12 score: -0.2 bits; conditional E-value: 1.9 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellk 27 e++++++ +D + ++++ Ef++ ++ FUN_001423-T1 841 EFDKLMARLDIQKGARLNYREFLKRFQ 867 79999999999999999****998665 PP == domain 13 score: 17.9 bits; conditional E-value: 3.1e-06 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkk 28 l ++F fD Dg+G ++++E++++l k FUN_001423-T1 914 LAKAFLAFDHDGNGIVTKKELRKVLYK 940 679********************9976 PP == domain 14 score: 22.7 bits; conditional E-value: 9.3e-08 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfke 24 e+k++++++D+D++G++d +Ef++ FUN_001423-T1 949 EFKKLWDKYDTDRNGYVDHQEFLA 972 79********************86 PP == domain 15 score: 23.8 bits; conditional E-value: 4.1e-08 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkell 26 l+++F+ +D ++dG+I+++E++++l FUN_001423-T1 1043 LRKAFETVDANRDGYISRQELQKVL 1067 79********************987 PP == domain 16 score: 11.0 bits; conditional E-value: 0.00048 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkk 28 ++++F+ fD+ g+G I++e++ +++++ FUN_001423-T1 1154 IRRAFAAFDRYGNGLISKEDLHQIINA 1180 799******************999875 PP == domain 17 score: -1.9 bits; conditional E-value: 6.6 EF-hand_1 15 GkIdfeEfke 24 G++++e+f + FUN_001423-T1 1203 GFVSYEDFFN 1212 99******76 PP == domain 18 score: 14.1 bits; conditional E-value: 5e-05 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkel 25 ++ i++++Dk+ dGk+d+ +f++ FUN_001423-T1 1306 FNHIWNLLDKNADGKVDYRDFLKR 1329 5679*****************875 PP == domain 19 score: 10.2 bits; conditional E-value: 0.00091 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellk 27 +++ Fr D + G ++fe+++++l FUN_001423-T1 1399 IQKSFRNTDSENKGVVNFEQLRDILL 1424 7899******************9985 PP == domain 20 score: 16.9 bits; conditional E-value: 6.2e-06 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkkl 29 ++++Fr +Dk g+G+ ++ +f+e+++k+ FUN_001423-T1 1509 MRRAFRALDKCGSGTCSLLQFREMMRKF 1536 589**********************985 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.0 3.1e-07 0.00022 1 28 [. 118 145 .. 118 147 .. 0.94 2 ? 2.4 0.0 0.35 2.5e+02 4 23 .. 157 176 .. 154 179 .. 0.80 3 ! 18.1 0.1 3.1e-06 0.0022 3 28 .. 228 253 .. 226 256 .. 0.90 4 ! 18.7 0.1 2e-06 0.0014 2 26 .. 349 373 .. 348 377 .. 0.91 5 ! 19.6 0.3 1e-06 0.00071 2 28 .. 461 487 .. 460 490 .. 0.92 6 ? 2.0 0.1 0.47 3.4e+02 2 23 .. 497 518 .. 496 522 .. 0.88 7 ! 15.9 0.0 1.5e-05 0.011 9 27 .. 575 593 .. 568 597 .. 0.88 8 ? 5.2 0.1 0.044 31 7 23 .. 609 625 .. 604 628 .. 0.87 9 ! 26.2 0.2 7.5e-09 5.4e-06 1 30 [] 696 725 .. 696 725 .. 0.96 10 ! 23.4 0.1 5.8e-08 4.1e-05 1 28 [. 805 832 .. 805 834 .. 0.93 11 ! 21.1 0.1 3.3e-07 0.00024 2 27 .. 914 939 .. 913 942 .. 0.91 12 ! 18.4 0.2 2.4e-06 0.0017 1 23 [. 949 971 .. 949 975 .. 0.93 13 ! 23.2 0.1 7.1e-08 5e-05 2 26 .. 1043 1067 .. 1042 1071 .. 0.93 14 ! 18.7 0.0 1.9e-06 0.0013 2 28 .. 1154 1180 .. 1153 1182 .. 0.92 15 ? -2.1 0.1 10 7.1e+03 12 27 .. 1200 1215 .. 1189 1218 .. 0.69 16 ? -2.1 0.0 9.9 7e+03 2 27 .. 1270 1295 .. 1269 1297 .. 0.84 17 ! 9.7 0.3 0.0016 1.1 2 24 .. 1306 1328 .. 1305 1332 .. 0.89 18 ! 8.5 0.1 0.0037 2.6 2 27 .. 1399 1424 .. 1398 1427 .. 0.90 19 ! 17.7 0.0 4e-06 0.0028 2 28 .. 1509 1535 .. 1508 1538 .. 0.94 20 ? -1.5 0.0 6.4 4.5e+03 4 19 .. 1547 1562 .. 1544 1568 .. 0.78 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 3.1e-07 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrs 28 elr+aF+ fD +++ +i+ +E+++al+s FUN_001423-T1 118 ELRQAFQTFDSEKTHTITQSEFKRALES 145 79************************86 PP == domain 2 score: 2.4 bits; conditional E-value: 0.35 EF-hand_6 4 eaFklfDkdgdGyisleElr 23 ++ ++ +++dG++s+ E+ FUN_001423-T1 157 QLIRKVGTNRDGTVSYLEFL 176 55566669**********96 PP == domain 3 score: 18.1 bits; conditional E-value: 3.1e-06 EF-hand_6 3 reaFklfDkdgdGyisleElraalrs 28 ++a +lfD ++dG+i ++Elr+++++ FUN_001423-T1 228 MKALRLFDYNRDGKIQRHELRRVIEN 253 6899******************9875 PP == domain 4 score: 18.7 bits; conditional E-value: 2e-06 EF-hand_6 2 lreaFklfDkdgdGyisleElraal 26 + +aF fD+ gdG+++l+El+++l FUN_001423-T1 349 ISRAFVAFDTRGDGFVTLDELKRVL 373 5689*******************98 PP == domain 5 score: 19.6 bits; conditional E-value: 1e-06 EF-hand_6 2 lreaFklfDkdgdGyisleElraalrs 28 +++aF +fD ++dG++++ ++r++l+s FUN_001423-T1 461 VKQAFLVFDDNKDGRVTKRDFRRVLES 487 589**********************86 PP == domain 6 score: 2.0 bits; conditional E-value: 0.47 EF-hand_6 2 lreaFklfDkdgdGyisleElr 23 ++e+ ++D ++Gy+s+ ++ FUN_001423-T1 497 FHELMAKIDPYNKGYVSYLDFL 518 7889999***********9996 PP == domain 7 score: 15.9 bits; conditional E-value: 1.5e-05 EF-hand_6 9 fDkdgdGyisleElraalr 27 D+d+dG+is++Elr++l+ FUN_001423-T1 575 VDTDRDGSISRSELRQLLE 593 6****************98 PP == domain 8 score: 5.2 bits; conditional E-value: 0.044 EF-hand_6 7 klfDkdgdGyisleElr 23 ++ D + dG+i+++E+ FUN_001423-T1 609 SRCDENADGSIDFQEFL 625 678************95 PP == domain 9 score: 26.2 bits; conditional E-value: 7.5e-09 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrslG 30 +lr+ F +fD +gdG+is++E+r +++slG FUN_001423-T1 696 DLRKTFVKFDSNGDGKISRKEFRMVMNSLG 725 589************************998 PP == domain 10 score: 23.4 bits; conditional E-value: 5.8e-08 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrs 28 +lr aF+++D d++G++++ E+r++l s FUN_001423-T1 805 DLRAAFQKIDYDRNGFVTRPEFRRILDS 832 599**********************986 PP == domain 11 score: 21.1 bits; conditional E-value: 3.3e-07 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 l +aF fD+dg+G ++++Elr++l FUN_001423-T1 914 LAKAFLAFDHDGNGIVTKKELRKVLY 939 789********************995 PP == domain 12 score: 18.4 bits; conditional E-value: 2.4e-06 EF-hand_6 1 elreaFklfDkdgdGyisleElr 23 e++++++++D+d++Gy++ +E+ FUN_001423-T1 949 EFKKLWDKYDTDRNGYVDHQEFL 971 699******************97 PP == domain 13 score: 23.2 bits; conditional E-value: 7.1e-08 EF-hand_6 2 lreaFklfDkdgdGyisleElraal 26 lr+aF+ D ++dGyis++El+++l FUN_001423-T1 1043 LRKAFETVDANRDGYISRQELQKVL 1067 89*********************98 PP == domain 14 score: 18.7 bits; conditional E-value: 1.9e-06 EF-hand_6 2 lreaFklfDkdgdGyisleElraalrs 28 +r+aF fD+ g+G is+e+l +++++ FUN_001423-T1 1154 IRRAFAAFDRYGNGLISKEDLHQIINA 1180 89*********************9875 PP == domain 15 score: -2.1 bits; conditional E-value: 10 EF-hand_6 12 dgdGyisleElraalr 27 G++s+e++ + ++ FUN_001423-T1 1200 SEGGFVSYEDFFNSFQ 1215 5568999999987665 PP == domain 16 score: -2.1 bits; conditional E-value: 9.9 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 l +aF D ++G++ + l ++l+ FUN_001423-T1 1270 LAKAFTDGDPRHTGTVGPSALHEILN 1295 66889999999****99998888886 PP == domain 17 score: 9.7 bits; conditional E-value: 0.0016 EF-hand_6 2 lreaFklfDkdgdGyisleElra 24 + ++++l+Dk+ dG++++ ++ + FUN_001423-T1 1306 FNHIWNLLDKNADGKVDYRDFLK 1328 67899**************9975 PP == domain 18 score: 8.5 bits; conditional E-value: 0.0037 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 +++ F+ D +++G +++e+lr++l FUN_001423-T1 1399 IQKSFRNTDSENKGVVNFEQLRDILL 1424 6789*******************996 PP == domain 19 score: 17.7 bits; conditional E-value: 4e-06 EF-hand_6 2 lreaFklfDkdgdGyisleElraalrs 28 +r+aF+ +Dk g+G+ sl ++r+++r+ FUN_001423-T1 1509 MRRAFRALDKCGSGTCSLLQFREMMRK 1535 79***********************96 PP == domain 20 score: -1.5 bits; conditional E-value: 6.4 EF-hand_6 4 eaFklfDkdgdGyisl 19 ++F+ +Dk +G++ + FUN_001423-T1 1547 HLFSYYDKLLTGKVCY 1562 79******99998865 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.069 49 10 21 .. 164 175 .. 156 177 .. 0.92 2 ! 20.9 0.0 3.4e-07 0.00024 2 24 .. 229 250 .. 228 251 .. 0.90 3 ! 14.3 0.0 4.2e-05 0.03 4 25 .] 352 373 .. 349 373 .. 0.91 4 ! 17.8 0.2 3.2e-06 0.0023 2 25 .] 462 485 .. 461 485 .. 0.91 5 ! 18.3 0.0 2.3e-06 0.0016 8 25 .] 575 592 .. 575 592 .. 0.93 6 ! 7.1 0.1 0.0081 5.8 9 21 .. 612 624 .. 610 626 .. 0.94 7 ! 27.9 0.1 2.1e-09 1.5e-06 1 25 [] 697 721 .. 697 721 .. 0.94 8 ! 21.1 0.0 2.9e-07 0.00021 1 24 [. 806 829 .. 806 830 .. 0.93 9 ! 16.4 0.0 9e-06 0.0064 2 25 .] 915 938 .. 914 938 .. 0.90 10 ? -1.8 0.1 5.4 3.8e+03 17 24 .. 946 953 .. 945 954 .. 0.83 11 ! 9.0 0.0 0.002 1.4 6 21 .. 955 970 .. 955 974 .. 0.90 12 ! 26.2 0.0 7.1e-09 5e-06 1 25 [] 1043 1067 .. 1043 1067 .. 0.92 13 ! 8.1 0.0 0.0039 2.8 2 23 .. 1155 1176 .. 1154 1178 .. 0.87 14 ? 6.5 0.1 0.012 8.7 7 22 .. 1312 1327 .. 1311 1331 .. 0.82 15 ? -2.2 0.0 7.3 5.2e+03 3 14 .. 1511 1522 .. 1509 1523 .. 0.73 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.069 EF-hand_5 10 lNgDGkIskeEL 21 +N+DG++s E+ FUN_001423-T1 164 TNRDGTVSYLEF 175 7*********99 PP == domain 2 score: 20.9 bits; conditional E-value: 3.4e-07 EF-hand_5 2 kdtFraiDlNgDGkIskeELkrl 24 k+ +r +D N+DGkI + EL+r+ FUN_001423-T1 229 KA-LRLFDYNRDGKIQRHELRRV 250 45.99****************97 PP == domain 3 score: 14.3 bits; conditional E-value: 4.2e-05 EF-hand_5 4 tFraiDlNgDGkIskeELkrll 25 +F a+D+ gDG+++ +ELkr+l FUN_001423-T1 352 AFVAFDTRGDGFVTLDELKRVL 373 499*****************85 PP == domain 4 score: 17.8 bits; conditional E-value: 3.2e-06 EF-hand_5 2 kdtFraiDlNgDGkIskeELkrll 25 k++F +D N+DG+++k ++r+l FUN_001423-T1 462 KQAFLVFDDNKDGRVTKRDFRRVL 485 568*******************85 PP == domain 5 score: 18.3 bits; conditional E-value: 2.3e-06 EF-hand_5 8 iDlNgDGkIskeELkrll 25 +D+++DG Is++EL++ll FUN_001423-T1 575 VDTDRDGSISRSELRQLL 592 6**************985 PP == domain 6 score: 7.1 bits; conditional E-value: 0.0081 EF-hand_5 9 DlNgDGkIskeEL 21 D N DG I+++E+ FUN_001423-T1 612 DENADGSIDFQEF 624 88**********9 PP == domain 7 score: 27.9 bits; conditional E-value: 2.1e-09 EF-hand_5 1 lkdtFraiDlNgDGkIskeELkrll 25 l++tF ++D NgDGkIs++E++ ++ FUN_001423-T1 697 LRKTFVKFDSNGDGKISRKEFRMVM 721 6899******************987 PP == domain 8 score: 21.1 bits; conditional E-value: 2.9e-07 EF-hand_5 1 lkdtFraiDlNgDGkIskeELkrl 24 l+++F++iD +++G++++ E++r+ FUN_001423-T1 806 LRAAFQKIDYDRNGFVTRPEFRRI 829 7899******************97 PP == domain 9 score: 16.4 bits; conditional E-value: 9e-06 EF-hand_5 2 kdtFraiDlNgDGkIskeELkrll 25 ++F a+D +g+G ++k+EL+++l FUN_001423-T1 915 AKAFLAFDHDGNGIVTKKELRKVL 938 557******************985 PP == domain 10 score: -1.8 bits; conditional E-value: 5.4 EF-hand_5 17 skeELkrl 24 +keE+k+l FUN_001423-T1 946 NKEEFKKL 953 79****98 PP == domain 11 score: 9.0 bits; conditional E-value: 0.002 EF-hand_5 6 raiDlNgDGkIskeEL 21 +++D++++G+++ +E+ FUN_001423-T1 955 DKYDTDRNGYVDHQEF 970 589************9 PP == domain 12 score: 26.2 bits; conditional E-value: 7.1e-09 EF-hand_5 1 lkdtFraiDlNgDGkIskeELkrll 25 l+++F+ +D+N+DG+Is++EL+++l FUN_001423-T1 1043 LRKAFETVDANRDGYISRQELQKVL 1067 6788******************985 PP == domain 13 score: 8.1 bits; conditional E-value: 0.0039 EF-hand_5 2 kdtFraiDlNgDGkIskeELkr 23 + +F a+D+ g+G Iske L + FUN_001423-T1 1155 RRAFAAFDRYGNGLISKEDLHQ 1176 567****************987 PP == domain 14 score: 6.5 bits; conditional E-value: 0.012 EF-hand_5 7 aiDlNgDGkIskeELk 22 +D+N DGk++ + FUN_001423-T1 1312 LLDKNADGKVDYRDFL 1327 68*********98885 PP == domain 15 score: -2.2 bits; conditional E-value: 7.3 EF-hand_5 3 dtFraiDlNgDG 14 +Fra+D+ g+G FUN_001423-T1 1511 RAFRALDKCGSG 1522 46*****86655 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.039 28 19 52 .. 112 144 .. 106 146 .. 0.87 2 ? 6.8 0.0 0.011 7.6 4 52 .. 133 180 .. 130 182 .. 0.89 3 ? 3.2 0.0 0.14 1e+02 31 48 .. 231 248 .. 214 253 .. 0.79 4 ? 6.9 0.0 0.011 7.5 27 52 .. 349 374 .. 334 375 .. 0.78 5 ! 7.6 0.1 0.0063 4.5 31 52 .. 465 486 .. 459 488 .. 0.90 6 ? 1.4 0.0 0.55 3.9e+02 22 53 .. 492 523 .. 489 524 .. 0.86 7 ! 10.4 0.0 0.00086 0.61 34 53 .. 575 594 .. 574 595 .. 0.94 8 ? 5.3 0.2 0.032 22 23 48 .. 600 625 .. 597 628 .. 0.81 9 ! 10.7 0.1 0.00067 0.48 34 52 .. 704 722 .. 701 724 .. 0.89 10 ? -1.7 0.0 5 3.5e+03 39 50 .. 744 755 .. 743 759 .. 0.80 11 ? 2.9 0.1 0.18 1.3e+02 29 49 .. 808 828 .. 793 866 .. 0.69 12 ! 9.0 0.0 0.0022 1.6 31 53 .. 918 940 .. 910 941 .. 0.85 13 ? 5.9 0.0 0.021 15 34 50 .. 957 973 .. 942 975 .. 0.80 14 ? 4.5 0.0 0.058 41 31 51 .. 1047 1067 .. 1041 1069 .. 0.83 15 ? 5.2 0.0 0.034 24 23 49 .. 1150 1176 .. 1138 1180 .. 0.84 16 ? 3.9 0.0 0.088 63 16 48 .. 1293 1327 .. 1282 1331 .. 0.83 17 ? 0.9 0.0 0.79 5.6e+02 31 49 .. 1403 1421 .. 1399 1426 .. 0.81 18 ? 2.1 0.1 0.34 2.4e+02 10 35 .. 1529 1553 .. 1528 1560 .. 0.74 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.039 EF-hand_8 19 lqdlsedevdtlfrefDtDgdGkisfeeFcvlle 52 ++ ++ e++ f++fD ++ +i++ eF+ +le FUN_001423-T1 112 IR-VNSAELRQAFQTFDSEKTHTITQSEFKRALE 144 34.89999**********************9987 PP == domain 2 score: 6.8 bits; conditional E-value: 0.011 EF-hand_8 4 vItresLkril.alLglqdlsedevdtlfrefDtDgdGkisfeeFcvlle 52 It ++kr+l + ++ l++d++ l+r t++dG++s eF++ + FUN_001423-T1 133 TITQSEFKRALeSF-CIP-LTDDQFEQLIRKVGTNRDGTVSYLEFLDRYH 180 79999****99666.799.**************************99875 PP == domain 3 score: 3.2 bits; conditional E-value: 0.14 EF-hand_8 31 frefDtDgdGkisfeeFc 48 +r fD ++dGki e+ FUN_001423-T1 231 LRLFDYNRDGKIQRHELR 248 799*********988876 PP == domain 4 score: 6.9 bits; conditional E-value: 0.011 EF-hand_8 27 vdtlfrefDtDgdGkisfeeFcvlle 52 ++ f +fDt gdG ++++e++ +l+ FUN_001423-T1 349 ISRAFVAFDTRGDGFVTLDELKRVLF 374 777899****************9998 PP == domain 5 score: 7.6 bits; conditional E-value: 0.0063 EF-hand_8 31 frefDtDgdGkisfeeFcvlle 52 f +fD ++dG +++ +F +le FUN_001423-T1 465 FLVFDDNKDGRVTKRDFRRVLE 486 668**************99987 PP == domain 6 score: 1.4 bits; conditional E-value: 0.55 EF-hand_8 22 lsedevdtlfrefDtDgdGkisfeeFcvller 53 +s +++ +l+ +D ++G++s +F++ +e+ FUN_001423-T1 492 MSHQQFHELMAKIDPYNKGYVSYLDFLDRFEQ 523 6777888888899*************999876 PP == domain 7 score: 10.4 bits; conditional E-value: 0.00086 EF-hand_8 34 fDtDgdGkisfeeFcvller 53 DtD+dG+is e+ +ller FUN_001423-T1 575 VDTDRDGSISRSELRQLLER 594 6*****************97 PP == domain 8 score: 5.3 bits; conditional E-value: 0.032 EF-hand_8 23 sedevdtlfrefDtDgdGkisfeeFc 48 s+d +d + + D++ dG+i+f eF+ FUN_001423-T1 600 SDDHFDLMWSRCDENADGSIDFQEFL 625 566667777778*************7 PP == domain 9 score: 10.7 bits; conditional E-value: 0.00067 EF-hand_8 34 fDtDgdGkisfeeFcvlle 52 fD +gdGkis +eF +++ FUN_001423-T1 704 FDSNGDGKISRKEFRMVMN 722 9*************98776 PP == domain 10 score: -1.7 bits; conditional E-value: 5 EF-hand_8 39 dGkisfeeFcvl 50 Gk+s +eF++ FUN_001423-T1 744 RGKLSYMEFLNN 755 7********875 PP == domain 11 score: 2.9 bits; conditional E-value: 0.18 EF-hand_8 29 tlfrefDtDgdGkisfeeFcv 49 + f+ +D D++G ++ eF FUN_001423-T1 808 AAFQKIDYDRNGFVTRPEFRR 828 555666666666666655543 PP == domain 12 score: 9.0 bits; conditional E-value: 0.0022 EF-hand_8 31 frefDtDgdGkisfeeFcvller 53 f +fD Dg+G+++++e+ +l++ FUN_001423-T1 918 FLAFDHDGNGIVTKKELRKVLYK 940 779*************9998877 PP == domain 13 score: 5.9 bits; conditional E-value: 0.021 EF-hand_8 34 fDtDgdGkisfeeFcvl 50 DtD++G+++ eF+ FUN_001423-T1 957 YDTDRNGYVDHQEFLAR 973 5*************865 PP == domain 14 score: 4.5 bits; conditional E-value: 0.058 EF-hand_8 31 frefDtDgdGkisfeeFcvll 51 f + D ++dG+is e+ +l FUN_001423-T1 1047 FETVDANRDGYISRQELQKVL 1067 7889*********99986665 PP == domain 15 score: 5.2 bits; conditional E-value: 0.034 EF-hand_8 23 sedevdtlfrefDtDgdGkisfeeFcv 49 + ++++ f +fD+ g+G is+e++++ FUN_001423-T1 1150 NPETIRRAFAAFDRYGNGLISKEDLHQ 1176 566788899***************997 PP == domain 16 score: 3.9 bits; conditional E-value: 0.088 EF-hand_8 16 lLglqd..lsedevdtlfrefDtDgdGkisfeeFc 48 +L+ + ++ d+++++ + +D + dGk++ +F+ FUN_001423-T1 1293 ILNEHAfrMTSDQFNHIWNLLDKNADGKVDYRDFL 1327 445666779*********************99997 PP == domain 17 score: 0.9 bits; conditional E-value: 0.79 EF-hand_8 31 frefDtDgdGkisfeeFcv 49 fr D +++G+++fe + + FUN_001423-T1 1403 FRNTDSENKGVVNFEQLRD 1421 6667999******997665 PP == domain 18 score: 2.1 bits; conditional E-value: 0.34 EF-hand_8 10 LkrilalLglqdlsedevdtlfrefD 35 +++ +++ ++ dlse+++++lf++ D FUN_001423-T1 1529 FREMMRKFKI-DLSEEDYFHLFSYYD 1553 5665655344.4**********9988 PP >> EF-hand_EFHB_C EFHB C-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.19 1.4e+02 25 66 .. 136 176 .. 126 182 .. 0.83 2 ! 13.2 0.0 0.00012 0.085 24 53 .. 243 272 .. 237 285 .. 0.88 3 ? -2.0 0.0 6.6 4.7e+03 26 47 .. 367 388 .. 365 392 .. 0.88 4 ? 1.3 0.0 0.62 4.4e+02 24 65 .. 477 517 .. 470 525 .. 0.79 5 ! 7.4 0.0 0.0074 5.2 24 53 .. 584 613 .. 576 626 .. 0.86 6 ? 1.3 0.0 0.61 4.3e+02 24 67 .. 713 754 .. 706 760 .. 0.73 7 ? 1.3 0.0 0.6 4.3e+02 26 49 .. 824 847 .. 817 857 .. 0.87 8 ! 9.7 0.0 0.0015 1 24 60 .. 930 965 .. 924 974 .. 0.85 9 ? -1.9 0.0 6 4.2e+03 26 71 .. 1061 1105 .. 1059 1107 .. 0.67 10 ! 11.6 0.2 0.00035 0.25 24 72 .. 1170 1217 .. 1166 1220 .. 0.91 11 ! 8.0 0.0 0.0049 3.5 28 65 .. 1290 1326 .. 1286 1331 .. 0.83 12 ? 4.6 0.0 0.054 38 26 58 .. 1417 1448 .. 1415 1459 .. 0.82 13 ? 0.5 0.0 1 7.4e+02 57 73 .. 1521 1537 .. 1508 1568 .. 0.71 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.19 EF-hand_EFHB_C 25 keeirrifenigvklsdetFeeiWkeaskkdpkgevsvesFr 66 + e +r +e+ + l+d++Fe++ +++ ++ +g vs+ +F FUN_001423-T1 136 QSEFKRALESFCIPLTDDQFEQLIRKVG-TNRDGTVSYLEFL 176 66777888888999***********998.588999*999986 PP == domain 2 score: 13.2 bits; conditional E-value: 0.00012 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeask 53 +++e+rr+ en ++l+de+F+++W + + FUN_001423-T1 243 QRHELRRVIENFCFRLTDEQFDKLWSKYDM 272 579**********************98766 PP == domain 3 score: -2.0 bits; conditional E-value: 6.6 EF-hand_EFHB_C 26 eeirrifenigvklsdetFeei 47 +e++r++ n + +sd+ F e+ FUN_001423-T1 367 DELKRVLFNFAFPMSDKLFVEL 388 89***************99876 PP == domain 4 score: 1.3 bits; conditional E-value: 0.62 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeaskkdpkgevsvesF 65 +k + rr++e+ +++s+++F e+ +++ + kg vs+ +F FUN_001423-T1 477 TKRDFRRVLESFCFRMSHQQFHELMAKIDPY-NKGYVSYLDF 517 5777899999999999999999998888654.4677777777 PP == domain 5 score: 7.4 bits; conditional E-value: 0.0074 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeask 53 s+ e+r+++e+ + +sd+ F+ +W + + FUN_001423-T1 584 SRSELRQLLERFCLPVSDDHFDLMWSRCDE 613 6789*********************98764 PP == domain 6 score: 1.3 bits; conditional E-value: 0.61 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeaskkdpkgevsvesFrn 67 s++e r ++++ g+ ++d++F + ++ ++g+ s+ +F n FUN_001423-T1 713 SRKEFRMVMNSLGLYMTDDQFRILSARLG--FHRGKLSYMEFLN 754 56778888888888888888888777666..3567777776665 PP == domain 7 score: 1.3 bits; conditional E-value: 0.6 EF-hand_EFHB_C 26 eeirrifenigvklsdetFeeiWk 49 e rri+ + + lsde+F+++ + FUN_001423-T1 824 PEFRRILDSFMIMLSDEEFDKLMA 847 5789****************9865 PP == domain 8 score: 9.7 bits; conditional E-value: 0.0015 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeaskkdpkgev 60 +k+e+r+++ + + l++e+F+++W++ +d +g v FUN_001423-T1 930 TKKELRKVLYKYQIPLNKEEFKKLWDKYD-TDRNGYV 965 79************************986.5667666 PP == domain 9 score: -1.9 bits; conditional E-value: 6 EF-hand_EFHB_C 26 eeirrifenigvklsdetFeeiWkeaskkdpkgevsvesFrnalde 71 +e+++++ + + l+d +++ + ++ + k++ s+e F +a ++ FUN_001423-T1 1061 QELQKVLFDFHYFLDDVQLNILLDRCGLSH-KNKLSYEKFLSAFQD 1105 566666666666666666666666666545.6669*****999876 PP == domain 10 score: 11.6 bits; conditional E-value: 0.00035 EF-hand_EFHB_C 24 skeeirrifenigvklsdetFeeiWkeaskkdpkgevsvesFrnaldel 72 ske++ +i ++ + +sd++F+++ k+++ ++ g vs+e+F n ++ FUN_001423-T1 1170 SKEDLHQIINAFCFIMSDKQFQALLKKIK-ISEGGFVSYEDFFNSFQKS 1217 89**************************8.7899********9988775 PP == domain 11 score: 8.0 bits; conditional E-value: 0.0049 EF-hand_EFHB_C 28 irrifenigvklsdetFeeiWkeaskkdpkgevsvesF 65 + +i+++ ++++ ++F++iW+ k+ +g+v +++F FUN_001423-T1 1290 LHEILNEHAFRMTSDQFNHIWNLLD-KNADGKVDYRDF 1326 678999999*************997.577888877777 PP == domain 12 score: 4.6 bits; conditional E-value: 0.054 EF-hand_EFHB_C 26 eeirrifenigvklsdetFeeiWkeaskkdpkg 58 e++r+i+ + +++ls +F ++W++ s++ kg FUN_001423-T1 1417 EQLRDILLKHDIELSPREFLSLWRKHSNE-GKG 1448 89**********************99864.444 PP == domain 13 score: 0.5 bits; conditional E-value: 1 EF-hand_EFHB_C 57 kgevsvesFrnaldelq 73 g +s+ +Fr+++++++ FUN_001423-T1 1521 SGTCSLLQFREMMRKFK 1537 56777777777776654 PP >> AIF-1 Allograft inflammatory factor 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 0.00019 0.13 37 101 .. 113 177 .. 101 182 .. 0.90 2 ! 14.2 0.6 7.6e-05 0.054 30 103 .. 214 288 .. 196 308 .. 0.84 3 ? 2.6 0.1 0.3 2.1e+02 42 101 .. 348 407 .. 331 411 .. 0.86 4 ! 15.6 0.1 2.8e-05 0.02 37 101 .. 455 519 .. 444 526 .. 0.92 5 ? 4.3 0.0 0.086 61 36 100 .. 561 625 .. 551 631 .. 0.79 6 ! 14.5 1.3 6.3e-05 0.045 8 107 .. 654 760 .. 649 773 .. 0.79 7 ? 3.4 0.2 0.17 1.2e+02 34 101 .. 797 864 .. 781 868 .. 0.91 8 ? 6.8 0.1 0.014 10 40 103 .. 911 974 .. 891 980 .. 0.87 9 ? 1.4 0.0 0.7 5e+02 37 103 .. 1037 1103 .. 1020 1111 .. 0.88 10 ? 5.1 0.0 0.052 37 36 101 .. 1147 1212 .. 1141 1220 .. 0.93 11 ? -1.8 0.0 6.9 4.9e+03 43 102 .. 1270 1329 .. 1253 1340 .. 0.65 12 ? 2.0 0.0 0.44 3.1e+02 39 102 .. 1395 1458 .. 1382 1466 .. 0.88 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00019 AIF-1 37 eskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflk 101 + + +++ + fd +++ i +kr le + ++ t ++ +li++v ++ t+sy +fl+ FUN_001423-T1 113 RVNSAELRQAFQTFDSEKTHTITQSEFKRALESFCIPLTDDQFEQLIRKVGTNRDGTVSYLEFLD 177 55556788999****************************************************96 PP == domain 2 score: 14.2 bits; conditional E-value: 7.6e-05 AIF-1 30 ysdeedleskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisev.tggssetisyrdflkmm 103 + +++ +l++ k fd n +G+i+ l+r++e + t ++ kl s+ + + +t+ y dflk + FUN_001423-T1 214 DQLRKKMGGQLQSVMKALRLFDYNRDGKIQRHELRRVIENFCFRLTDEQFDKLWSKYdMTRNGQTLEYMDFLKRL 288 45556667788899999999**********************************9984566799********965 PP == domain 3 score: 2.6 bits; conditional E-value: 0.3 AIF-1 42 afkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflk 101 + + ++ fd ++G + l lkr+l + + + + l+s +++ i y +fl+ FUN_001423-T1 348 NISRAFVAFDTRGDGFVTLDELKRVLFNFAFPMSDKLFVELMSRCGIRANHKIPYVQFLE 407 556789************************999999999999999999999999999986 PP == domain 4 score: 15.6 bits; conditional E-value: 2.8e-05 AIF-1 37 eskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflk 101 + + + k+ ++ fd n++G + ++r+le + +h ++ l++++ ++ +sy dfl+ FUN_001423-T1 455 LNSFSSVKQAFLVFDDNKDGRVTKRDFRRVLESFCFRMSHQQFHELMAKIDPYNKGYVSYLDFLD 519 4567789********************************************************96 PP == domain 5 score: 4.3 bits; conditional E-value: 0.086 AIF-1 36 leskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdfl 100 ++++ +a+ y+ d + +G i l+++le++ ++ + + + s ++ +i +++fl FUN_001423-T1 561 ITDNWKAIASAYLGVDTDRDGSISRSELRQLLERFCLPVSDDHFDLMWSRCDENADGSIDFQEFL 625 45566777889**********************98777666666667777777777788888876 PP == domain 6 score: 14.5 bits; conditional E-value: 6.3e-05 AIF-1 8 llkaqqeekleeinkefl..edekysde......edleskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetis 95 +lk+ q+ +le +++ l + +k ++e e ++++ + ++k +++fd n++G+i ++ +++ lG+ t +++ ++s g + +s FUN_001423-T1 654 FLKQDQNARLELVDERALnlTGQKSANEcmeilkEYISQRSTDLRKTFVKFDSNGDGKISRKEFRMVMNSLGLYMTDDQFR-ILSARLGFHRGKLS 748 799999999999998765115667665433222245566677899*******************************98876.66667788889999 PP AIF-1 96 yrdflkmmlGkr 107 y +fl+ + +r FUN_001423-T1 749 YMEFLNNFQDRR 760 *99999877666 PP == domain 7 score: 3.4 bits; conditional E-value: 0.17 AIF-1 34 edleskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflk 101 +l+++++ ++ + ++d + +G + ++r+l+ + + + e+ kl++ + + ++yr+flk FUN_001423-T1 797 TKLRENFQDLRAAFQKIDYDRNGFVTRPEFRRILDSFMIMLSDEEFDKLMARLDIQKGARLNYREFLK 864 56888888899999999*************************************************98 PP == domain 8 score: 6.8 bits; conditional E-value: 0.014 AIF-1 40 leafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmm 103 e + k ++ fd +++G + l+++l k ++ + e+kkl + ++ + + +++fl + FUN_001423-T1 911 NEDLAKAFLAFDHDGNGIVTKKELRKVLYKYQIPLNKEEFKKLWDKYDTDRNGYVDHQEFLARL 974 5667889*************************************99999999999999988765 PP == domain 9 score: 1.4 bits; conditional E-value: 0.7 AIF-1 37 eskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmm 103 ++ e+++k + d n +G i l+++l + ++l l+ + ++ +sy+ fl + FUN_001423-T1 1037 RDGYESLRKAFETVDANRDGYISRQELQKVLFDFHYFLDDVQLNILLDRCGLSHKNKLSYEKFLSAF 1103 556789999999**********************99999999999999999999*******999765 PP == domain 10 score: 5.1 bits; conditional E-value: 0.052 AIF-1 36 leskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflk 101 ++++ e++++ ++ fd+ ++G i l ++++ + + +++ l++++ + +sy+df + FUN_001423-T1 1147 ISENPETIRRAFAAFDRYGNGLISKEDLHQIINAFCFIMSDKQFQALLKKIKISEGGFVSYEDFFN 1212 5677789999******************************************************87 PP == domain 11 score: -1.8 bits; conditional E-value: 6.9 AIF-1 43 fkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkm 102 + k + + d ++G + +l +l+ t ++ + + + +++ + yrdflk FUN_001423-T1 1270 LAKAFTDGDPRHTGTVGPSALHEILNEHAFRMTSDQFNHIWNLLDKNADGKVDYRDFLKR 1329 555566666666666666666666666666666666666666666777777788888775 PP == domain 12 score: 2.0 bits; conditional E-value: 0.44 AIF-1 39 kleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkm 102 + + ++k + + d +++G +++ l+ +l k + + e+ l ++ +++ + i y+df++ FUN_001423-T1 1395 RWQHIQKSFRNTDSENKGVVNFEQLRDILLKHDIELSPREFLSLWRKHSNEGKGGIVYKDFMRH 1458 556778899999*************************************************985 PP >> EH EH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 3.7 2.6e+03 8 62 .. 118 175 .. 113 176 .. 0.79 2 ? 3.8 0.0 0.11 76 20 56 .. 239 277 .. 228 287 .. 0.79 3 ! 14.0 0.0 7.1e-05 0.05 18 63 .. 578 625 .. 569 662 .. 0.74 4 ? 0.8 0.0 0.92 6.6e+02 39 67 .. 694 722 .. 675 735 .. 0.83 5 ? -2.4 0.0 9.3 6.6e+03 11 63 .. 808 863 .. 800 872 .. 0.76 6 ! 19.3 0.1 1.7e-06 0.0012 17 64 .. 923 972 .. 905 975 .. 0.81 7 ? 1.0 0.0 0.79 5.6e+02 42 62 .. 1043 1063 .. 1034 1127 .. 0.64 8 ! 14.6 0.0 4.7e-05 0.034 33 63 .. 1297 1327 .. 1264 1343 .. 0.78 9 ? -1.2 0.0 4 2.9e+03 11 58 .. 1401 1451 .. 1396 1463 .. 0.66 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 3.7 EH 8 kyweifsglkpenk.kltgskvapvLkns..kLeqdqLakiWdlaDidddGkLdfeef 62 + ++ f+ + e+ ++t+s+ + L ++ L +dq +++ + ++ dG++ ef FUN_001423-T1 118 ELRQAFQTFDSEKThTITQSEFKRALESFciPLTDDQFEQLIRKVGTNRDGTVSYLEF 175 5678899999888889999999999999833478999999988888888888776666 PP == domain 2 score: 3.8 bits; conditional E-value: 0.11 EH 20 nkkltgskvapvLkn..skLeqdqLakiWdlaDidddGk 56 + k++ ++ v+ n ++L ++q k+W D+ +G+ FUN_001423-T1 239 DGKIQRHELRRVIENfcFRLTDEQFDKLWSKYDMTRNGQ 277 4577788888888883359***************99996 PP == domain 3 score: 14.0 bits; conditional E-value: 7.1e-05 EH 18 penkkltgskvapvLknskLe..qdqLakiWdlaDidddGkLdfeefv 63 + + ++ s++ +L + L+ +d+ +W +D + dG++df+ef FUN_001423-T1 578 DRDGSISRSELRQLLERFCLPvsDDHFDLMWSRCDENADGSIDFQEFL 625 45558899999999999998543899*********************7 PP == domain 4 score: 0.8 bits; conditional E-value: 0.92 EH 39 qdqLakiWdlaDidddGkLdfeefviamr 67 + L k D++ dGk+ ++ef ++m FUN_001423-T1 694 STDLRKTFVKFDSNGDGKISRKEFRMVMN 722 56678888889*************99985 PP == domain 5 score: -2.4 bits; conditional E-value: 9.3 EH 11 eifsglkpenk.kltgskvapvLkns..kLeqdqLakiWdlaDidddGkLdfeefv 63 f++++ + + ++t + +L ++ L++++ k+ Di++ L+ ef FUN_001423-T1 808 AAFQKIDYDRNgFVTRPEFRRILDSFmiMLSDEEFDKLMARLDIQKGARLNYREFL 863 56777776666688888888888877335889999999999999999999998886 PP == domain 6 score: 19.3 bits; conditional E-value: 1.7e-06 EH 17 kpenkkltgskvapvLknsk..LeqdqLakiWdlaDidddGkLdfeefvi 64 ++ n ++t +++ vL + + L++++ +k+Wd D+d +G++d +ef + FUN_001423-T1 923 HDGNGIVTKKELRKVLYKYQipLNKEEFKKLWDKYDTDRNGYVDHQEFLA 972 4556699*********998855789***********************75 PP == domain 7 score: 1.0 bits; conditional E-value: 0.79 EH 42 LakiWdlaDidddGkLdfeef 62 L k +++D + dG++ ++e FUN_001423-T1 1043 LRKAFETVDANRDGYISRQEL 1063 555555555555555555443 PP == domain 8 score: 14.6 bits; conditional E-value: 4.7e-05 EH 33 knskLeqdqLakiWdlaDidddGkLdfeefv 63 +++++ +dq ++iW+l D + dGk+d +f FUN_001423-T1 1297 HAFRMTSDQFNHIWNLLDKNADGKVDYRDFL 1327 468999*********************9996 PP == domain 9 score: -1.2 bits; conditional E-value: 4 EH 11 eifsglkpenk.kltgskvapvLkns..kLeqdqLakiWdlaDidddGkLd 58 + f++ + enk +++ +++ +L++ +L+ + +W + +G + FUN_001423-T1 1401 KSFRNTDSENKgVVNFEQLRDILLKHdiELSPREFLSLWRKHSNEGKGGIV 1451 457777777777777788888877642256666777777766666666665 PP >> EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.1 0.086 61 33 62 .. 115 144 .. 101 178 .. 0.79 2 ? 5.0 0.2 0.06 42 34 63 .. 224 253 .. 210 305 .. 0.81 3 ? 1.7 0.0 0.66 4.7e+02 25 60 .. 337 372 .. 328 380 .. 0.82 4 ? 4.0 0.1 0.13 90 35 63 .. 459 487 .. 446 506 .. 0.79 5 ? 5.4 0.1 0.044 32 36 62 .. 567 593 .. 548 625 .. 0.62 6 ? 4.6 0.1 0.08 57 40 59 .. 607 626 .. 599 657 .. 0.83 7 ! 9.2 0.1 0.003 2.1 32 62 .. 692 722 .. 676 734 .. 0.83 8 ? 7.2 0.1 0.012 8.8 21 67 .. 790 836 .. 782 869 .. 0.73 9 ! 9.2 0.2 0.003 2.1 15 69 .. 892 946 .. 888 952 .. 0.85 10 ? 6.6 0.1 0.019 14 34 60 .. 947 973 .. 944 1003 .. 0.86 11 ! 10.1 0.1 0.0017 1.2 16 60 .. 1022 1066 .. 1016 1076 .. 0.80 12 ? -0.8 0.0 3.9 2.7e+03 34 63 .. 1151 1180 .. 1142 1202 .. 0.78 13 ? 2.9 0.0 0.26 1.9e+02 35 65 .. 1304 1334 .. 1292 1346 .. 0.78 14 ? -1.9 0.0 8.1 5.7e+03 36 65 .. 1398 1427 .. 1393 1440 .. 0.78 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.086 EF-hand_FSTL1 33 yrellekyFkavDknkdkkldskEllelve 62 ++ l + F+++D++k +++ ++E+ + +e FUN_001423-T1 115 NSAELRQAFQTFDSEKTHTITQSEFKRALE 144 5678999******************99887 PP == domain 2 score: 5.0 bits; conditional E-value: 0.06 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllelvek 63 +++ k + +D n+d+k++++El +++e+ FUN_001423-T1 224 LQSVMKALRLFDYNRDGKIQRHELRRVIEN 253 46677888999****************993 PP == domain 3 score: 1.7 bits; conditional E-value: 0.66 EF-hand_FSTL1 25 sllekgksyrellekyFkavDknkdkkldskEllel 60 +l ++ + + +++ F a+D+ d+++ +El ++ FUN_001423-T1 337 KLRKRMLENHGNISRAFVAFDTRGDGFVTLDELKRV 372 455566677888999*****************9765 PP == domain 4 score: 4.0 bits; conditional E-value: 0.13 EF-hand_FSTL1 35 ellekyFkavDknkdkkldskEllelvek 63 +++++ F +D+nkd+ + + ++ +++e+ FUN_001423-T1 459 SSVKQAFLVFDDNKDGRVTKRDFRRVLES 487 568899*****************999984 PP == domain 5 score: 5.4 bits; conditional E-value: 0.044 EF-hand_FSTL1 36 llekyFkavDknkdkkldskEllelve 62 + + + vD+++d++++++El +l+e FUN_001423-T1 567 AIASAYLGVDTDRDGSISRSELRQLLE 593 566667777777777777777777766 PP == domain 6 score: 4.6 bits; conditional E-value: 0.08 EF-hand_FSTL1 40 yFkavDknkdkkldskElle 59 +++++D+n d+++d +E+l FUN_001423-T1 607 MWSRCDENADGSIDFQEFLG 626 67889999999999999975 PP == domain 7 score: 9.2 bits; conditional E-value: 0.003 EF-hand_FSTL1 32 syrellekyFkavDknkdkkldskEllelve 62 + + l k+F ++D+n d+k+++kE+ +++ FUN_001423-T1 692 QRSTDLRKTFVKFDSNGDGKISRKEFRMVMN 722 4567799*******************88776 PP == domain 8 score: 7.2 bits; conditional E-value: 0.012 EF-hand_FSTL1 21 vekqsllekgksyrellekyFkavDknkdkkldskEllelveknetv 67 + + ++ +k + + l F+++D ++++++ + E+ +++++ +++ FUN_001423-T1 790 AVEAKMKTKLRENFQDLRAAFQKIDYDRNGFVTRPEFRRILDSFMIM 836 4555666677777788999*******************999844443 PP == domain 9 score: 9.2 bits; conditional E-value: 0.003 EF-hand_FSTL1 15 ewlkeevekqsllekgksyrellekyFkavDknkdkkldskEllelveknetvae 69 ++l++ ++++ + +k+ +++e l k F a+D++ ++ + +kEl +++ k ++ + FUN_001423-T1 892 TYLTAAQADDVIKRKAWEQNEDLAKAFLAFDHDGNGIVTKKELRKVLYKYQIPLN 946 5788888888889999999**************************9987666555 PP == domain 10 score: 6.6 bits; conditional E-value: 0.019 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllel 60 +e ++k ++++D+++++++d +E+l+ FUN_001423-T1 947 KEEFKKLWDKYDTDRNGYVDHQEFLAR 973 5778999*****************975 PP == domain 11 score: 10.1 bits; conditional E-value: 0.0017 EF-hand_FSTL1 16 wlkeevekqsllekgksyrellekyFkavDknkdkkldskEllel 60 +l++ +q+l ++ + e+l k F++vD+n+d++++++El ++ FUN_001423-T1 1022 FLSALEVEQRLRDRFRDGYESLRKAFETVDANRDGYISRQELQKV 1066 555555556666666777899*********************886 PP == domain 12 score: -0.8 bits; conditional E-value: 3.9 EF-hand_FSTL1 34 rellekyFkavDknkdkkldskEllelvek 63 e++ + F a+D+ ++ +++++l +++++ FUN_001423-T1 1151 PETIRRAFAAFDRYGNGLISKEDLHQIINA 1180 5678899*****************999983 PP == domain 13 score: 2.9 bits; conditional E-value: 0.26 EF-hand_FSTL1 35 ellekyFkavDknkdkkldskEllelvekne 65 + +++ ++ +Dkn d+k+d ++l+ ++++ FUN_001423-T1 1304 DQFNHIWNLLDKNADGKVDYRDFLKRFSTRT 1334 5677788999***********9999776544 PP == domain 14 score: -1.9 bits; conditional E-value: 8.1 EF-hand_FSTL1 36 llekyFkavDknkdkkldskEllelvekne 65 ++k+F++ D+++ + ++ + l +++ k++ FUN_001423-T1 1398 HIQKSFRNTDSENKGVVNFEQLRDILLKHD 1427 678999999999999998888888776555 PP >> Dockerin_1 Dockerin type I domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.026 19 20 54 .. 218 252 .. 214 255 .. 0.80 2 ? -0.2 0.0 2.4 1.7e+03 10 45 .. 329 365 .. 328 372 .. 0.77 3 ! 8.4 0.0 0.0047 3.3 25 52 .. 457 484 .. 449 487 .. 0.76 4 ? -0.5 0.0 2.9 2.1e+03 36 52 .. 575 591 .. 569 596 .. 0.81 5 ? 0.9 0.1 1.1 7.8e+02 4 45 .. 577 620 .. 575 625 .. 0.49 6 ! 12.4 0.0 0.00028 0.2 17 56 .. 685 724 .. 683 725 .. 0.87 7 ? -1.4 0.1 5.7 4e+03 27 48 .. 948 969 .. 920 972 .. 0.65 8 ? 1.8 0.0 0.56 4e+02 33 50 .. 1047 1064 .. 1016 1066 .. 0.81 9 ? 2.6 0.0 0.32 2.3e+02 24 55 .. 1149 1180 .. 1135 1182 .. 0.74 10 ? 5.0 0.1 0.055 39 35 50 .. 1312 1327 .. 1294 1328 .. 0.79 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.026 Dockerin_1 20 nyllgegtsssinkkaaDvNgDGkvnalDllllkn 54 + + g+ +s+ + + +D N+DGk+ l +++ FUN_001423-T1 218 KKMGGQLQSVMKALRLFDYNRDGKIQRHELRRVIE 252 55556667778888999*********999999986 PP == domain 2 score: -0.2 bits; conditional E-value: 2.4 Dockerin_1 10 VnalDall.lknyllgegtsssinkkaaDvNgDGkvn 45 V+ +D+ l++ +l++ + s a+D gDG v+ FUN_001423-T1 329 VTIMDLEQkLRKRMLENHGNISRAFVAFDTRGDGFVT 365 566666533778888788888999999*******998 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0047 Dockerin_1 25 egtsssinkkaaDvNgDGkvnalDllll 52 + +s+++ +D N+DG+v+++D+ ++ FUN_001423-T1 457 SFSSVKQAFLVFDDNKDGRVTKRDFRRV 484 55566666677899**********9876 PP == domain 4 score: -0.5 bits; conditional E-value: 2.9 Dockerin_1 36 aDvNgDGkvnalDllll 52 D ++DG+++ l +l FUN_001423-T1 575 VDTDRDGSISRSELRQL 591 59999999998877665 PP == domain 5 score: 0.9 bits; conditional E-value: 1.1 Dockerin_1 4 vNgDgkVnalDal.llknyll.gegtsssinkkaaDvNgDGkvn 45 ++Dg+++ + ll + l +++ + + ++D N DG+++ FUN_001423-T1 577 TDRDGSISRSELRqLLERFCLpVSDDHFDLMWSRCDENADGSID 620 44444444444431222333344455555556666777777766 PP == domain 6 score: 12.4 bits; conditional E-value: 0.00028 Dockerin_1 17 llknyllgegtsssinkkaaDvNgDGkvnalDllllknyL 56 +lk y+ + t + ++D NgDGk++ + +++n L FUN_001423-T1 685 ILKEYISQRSTDLRKTFVKFDSNGDGKISRKEFRMVMNSL 724 89999997777777888899*****************987 PP == domain 7 score: -1.4 bits; conditional E-value: 5.7 Dockerin_1 27 tsssinkkaaDvNgDGkvnalD 48 ++ ++ +++D +++G v+ FUN_001423-T1 948 EEFKKLWDKYDTDRNGYVDHQE 969 4445556678888888877665 PP == domain 8 score: 1.8 bits; conditional E-value: 0.56 Dockerin_1 33 kkaaDvNgDGkvnalDll 50 ++ D N+DG ++ l+ FUN_001423-T1 1047 FETVDANRDGYISRQELQ 1064 5789******99988776 PP == domain 9 score: 2.6 bits; conditional E-value: 0.32 Dockerin_1 24 gegtsssinkkaaDvNgDGkvnalDllllkny 55 +++++ +a+D g+G +++ Dl +++n+ FUN_001423-T1 1149 ENPETIRRAFAAFDRYGNGLISKEDLHQIINA 1180 5566666777899****************997 PP == domain 10 score: 5.0 bits; conditional E-value: 0.055 Dockerin_1 35 aaDvNgDGkvnalDll 50 +D N DGkv+ +D+l FUN_001423-T1 1312 LLDKNADGKVDYRDFL 1327 5788888888888876 PP >> DUF5580_M Family of unknown function (DUF5580) middle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.9 1.4e+03 15 75 .. 112 172 .. 102 181 .. 0.80 2 ? 0.1 0.0 1.8 1.2e+03 20 56 .. 695 731 .. 681 758 .. 0.80 3 ! 8.8 0.0 0.0033 2.4 14 81 .. 798 865 .. 789 874 .. 0.87 4 ? 0.8 0.0 1 7.4e+02 20 80 .. 912 972 .. 902 979 .. 0.86 5 ? 4.1 0.0 0.096 68 19 81 .. 1040 1102 .. 1028 1108 .. 0.93 6 ? 4.5 0.0 0.073 52 18 88 .. 1150 1220 .. 1138 1224 .. 0.88 7 ? 5.2 0.0 0.045 32 21 81 .. 1269 1329 .. 1260 1339 .. 0.91 8 ! 10.0 0.1 0.0014 1 21 80 .. 1398 1457 .. 1392 1468 .. 0.83 9 ? 0.1 0.0 1.7 1.2e+03 9 53 .. 1497 1540 .. 1490 1557 .. 0.79 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.9 DUF5580_M 15 gklnlenLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikW 75 ++n +L+ +f+ D + ++++++ + + + lt +e l+ + + + + FUN_001423-T1 112 IRVNSAELRQAFQTFDSEKTHTITQSEFKRALESFCIPLTDDQFEQLIRKVGTNRDGTVSY 172 5689999*****************9999999999999999888888888666666666655 PP == domain 2 score: 0.1 bits; conditional E-value: 1.8 DUF5580_M 20 enLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltls 56 L+ +f k D G +++++ r + + gly+t FUN_001423-T1 695 TDLRKTFVKFDSNGDGKISRKEFRMVMNSLGLYMTDD 731 4688999999*****************9999999865 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0033 DUF5580_M 14 kgklnlenLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvel 81 k + n + L+ +f+k D G++++p+ r i + ++l+ ++ l+ d++ ++++++++ FUN_001423-T1 798 KLRENFQDLRAAFQKIDYDRNGFVTRPEFRRILDSFMIMLSDEEFDKLMARLDIQKGARLNYREFLKR 865 44558999****************************************99999999999999988875 PP == domain 4 score: 0.8 bits; conditional E-value: 1 DUF5580_M 20 enLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlve 80 e L +f D+ G+++k+++r + k+ + l + l + d ++ + q+++ FUN_001423-T1 912 EDLAKAFLAFDHDGNGIVTKKELRKVLYKYQIPLNKEEFKKLWDKYDTDRNGYVDHQEFLA 972 7789999999*******************99999999999999988988888888888875 PP == domain 5 score: 4.1 bits; conditional E-value: 0.096 DUF5580_M 19 lenLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvel 81 e+L+ +f D G++++++++ + +l l+ ll+ l++++++ +++++ FUN_001423-T1 1040 YESLRKAFETVDANRDGYISRQELQKVLFDFHYFLDDVQLNILLDRCGLSHKNKLSYEKFLSA 1102 5899************************9999***************************9865 PP == domain 6 score: 4.5 bits; conditional E-value: 0.073 DUF5580_M 18 nlenLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvelLsrassd 88 n e+++++f Dr Gl++k++++ i + +++ + +ll+ +++ + + ++++ + ++++ ++ FUN_001423-T1 1150 NPETIRRAFAAFDRYGNGLISKEDLHQIINAFCFIMSDKQFQALLKKIKISEGGFVSYEDFFNSFQKSDTE 1220 67999*****************************************9999999999999999998887665 PP == domain 7 score: 5.2 bits; conditional E-value: 0.045 DUF5580_M 21 nLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlvel 81 +L +f + D +G++ ++ ++ i + h +t ++ + n d + +++ ++++++ FUN_001423-T1 1269 SLAKAFTDGDPRHTGTVGPSALHEILNEHAFRMTSDQFNHIWNLLDKNADGKVDYRDFLKR 1329 68899**************************************999999999999999875 PP == domain 8 score: 10.0 bits; conditional E-value: 0.0014 DUF5580_M 21 nLnlsfrkeDrsfsGlLpkpkvraiCgkhglyltlslletllnhqdlgyqdeikWqnlve 80 +++ sfr++D G++ +++r i kh + l++ + +l + + ++ i ++++++ FUN_001423-T1 1398 HIQKSFRNTDSENKGVVNFEQLRDILLKHDIELSPREFLSLWRKHSNEGKGGIVYKDFMR 1457 6889*****************************998666666666666677777888775 PP == domain 9 score: 0.1 bits; conditional E-value: 1.7 DUF5580_M 9 alktakgklnlenLnlsfrkeDrsfsGlLpkpkvraiCgkhglyl 53 al++ + + + ++++fr D+ sG+ + + r + k + l FUN_001423-T1 1497 ALRAP-VRRDWKAMRRAFRALDKCGSGTCSLLQFREMMRKFKIDL 1540 55543.34478899**************99999998888877665 PP >> EF-hand_9 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.89 6.3e+02 3 39 .. 122 157 .. 120 176 .. 0.78 2 ? 3.8 0.0 0.16 1.1e+02 2 32 .. 351 381 .. 350 391 .. 0.84 3 ! 11.9 0.0 0.00048 0.34 2 59 .. 463 518 .. 462 521 .. 0.89 4 ? 1.5 0.0 0.83 5.9e+02 7 58 .. 575 624 .. 570 626 .. 0.70 5 ? 1.7 0.0 0.72 5.1e+02 3 58 .. 917 970 .. 915 973 .. 0.70 6 ? -1.5 0.0 7.2 5.1e+03 2 29 .. 1156 1183 .. 1155 1197 .. 0.73 7 ? 3.0 0.0 0.29 2e+02 7 59 .. 1277 1327 .. 1272 1333 .. 0.75 8 ? -0.8 0.0 4.2 3e+03 3 24 .. 1402 1423 .. 1400 1435 .. 0.89 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.89 EF-hand_9 3 tFevcDtqktGeVpvskliayLravaaqdpqelelee 39 F+ +D +kt +++ s+ + L+ + + + e+ FUN_001423-T1 122 AFQTFDSEKTHTITQSEFKRALESFCIPLTD-DQFEQ 157 69*****************999998885444.34555 PP == domain 2 score: 3.8 bits; conditional E-value: 0.16 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaaqdp 32 + F ++Dt G V++ +l+ +L a ++ FUN_001423-T1 351 RAFVAFDTRGDGFVTLDELKRVLFNFAFPMS 381 5699*****************9988887765 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00048 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaaqdpqeleleelarelDPdgedatveldtFl 59 + F v+D +k G+V+ + +L+ + + el +++DP+++ + v +Fl FUN_001423-T1 463 QAFLVFDDNKDGRVTKRDFRRVLESFCF-RMSHQQFHELMAKIDPYNK-GYVSYLDFL 518 5699************************.778899*************.777766665 PP == domain 4 score: 1.5 bits; conditional E-value: 0.83 EF-hand_9 7 cDtqktGeVpvskliayLravaaqdpqel.eleelarelDPdgedatveldtF 58 Dt++ G + s+l ++L+ ++ ++ +l D + +++++ +F FUN_001423-T1 575 VDTDRDGSISRSELRQLLERFCLPVSDDHfDLM--WSRCDENAD-GSIDFQEF 624 69******************9997777775553..333443333.55666666 PP == domain 5 score: 1.7 bits; conditional E-value: 0.72 EF-hand_9 3 tFevcDtqktGeVpvskliayLravaaqdpqel.eleelarelDPdgedatveldtF 58 F ++D + G+V+ ++l ++L p + e ++l ++D d + + v+ +F FUN_001423-T1 917 AFLAFDHDGNGIVTKKELRKVLYKYQI--PLNKeEFKKLWDKYDTDRN-GYVDHQEF 970 4999************99999987766..3333356666666666655.66666665 PP == domain 6 score: -1.5 bits; conditional E-value: 7.2 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaa 29 + F ++D+ G + +l ++ a FUN_001423-T1 1156 RAFAAFDRYGNGLISKEDLHQIINAFCF 1183 5699999999999988888888777655 PP == domain 7 score: 3.0 bits; conditional E-value: 0.29 EF-hand_9 7 cDtqktGeVpvskliayLravaaqdpqeleleelarelDPdgedatveldtFl 59 D+ tG+V s l ++L a ++++ + lD + ++v+ +Fl FUN_001423-T1 1277 GDPRHTGTVGPSALHEILNEHAFRMTSDQ-FNHIWNLLDKNAD-GKVDYRDFL 1327 5999*******************999996.4445555665444.666666665 PP == domain 8 score: -0.8 bits; conditional E-value: 4.2 EF-hand_9 3 tFevcDtqktGeVpvskliayL 24 F+ D ++ G+V +l ++L FUN_001423-T1 1402 SFRNTDSENKGVVNFEQLRDIL 1423 59999*************9998 PP >> EF_EFCAB10_C EFCAB10, C-terminal EF-hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.0 0.0078 5.5 3 39 .. 119 155 .. 117 163 .. 0.84 2 ? -2.4 0.0 7.7 5.5e+03 23 47 .. 281 307 .. 279 309 .. 0.67 3 ? -0.1 0.0 1.5 1e+03 2 27 .. 348 373 .. 347 376 .. 0.85 4 ? -1.9 0.0 5.5 3.9e+03 4 29 .. 462 487 .. 459 489 .. 0.82 5 ? -2.4 0.0 7.5 5.3e+03 10 20 .. 504 514 .. 496 517 .. 0.87 6 ! 7.3 0.0 0.0072 5.1 3 38 .. 697 732 .. 695 737 .. 0.85 7 ? -0.6 0.0 2 1.4e+03 2 30 .. 805 833 .. 804 845 .. 0.80 8 ? -1.6 0.0 4.5 3.2e+03 4 21 .. 1044 1061 .. 1042 1067 .. 0.81 9 ? 0.5 0.0 0.95 6.8e+02 6 24 .. 1402 1420 .. 1397 1424 .. 0.81 10 ? 3.6 0.0 0.1 71 6 28 .. 1512 1534 .. 1507 1544 .. 0.88 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0078 EF_EFCAB10_C 3 ldamFemLDptgrGyItlaQYkeALkTLGlstedevl 39 l+ F+ +D+ + +It + +k AL+++ + d ++ FUN_001423-T1 119 LRQAFQTFDSEKTHTITQSEFKRALESFCIPLTDDQF 155 6778999*******************98877666665 PP == domain 2 score: -2.4 bits; conditional E-value: 7.7 EF_EFCAB10_C 23 YkeALkTLGlsted..evleddgdkIt 47 Y Lk LG++ + + ++d+++++ FUN_001423-T1 281 YMDFLKRLGVKAKSdiNKTGEDQEQVK 307 6777999***87541224567777776 PP == domain 3 score: -0.1 bits; conditional E-value: 1.5 EF_EFCAB10_C 2 NldamFemLDptgrGyItlaQYkeAL 27 N+ F +D+ g G++tl k L FUN_001423-T1 348 NISRAFVAFDTRGDGFVTLDELKRVL 373 888889999*********98777655 PP == domain 4 score: -1.9 bits; conditional E-value: 5.5 EF_EFCAB10_C 4 damFemLDptgrGyItlaQYkeALkT 29 + F ++D ++ G +t + ++ L++ FUN_001423-T1 462 KQAFLVFDDNKDGRVTKRDFRRVLES 487 56788999999999999999998875 PP == domain 5 score: -2.4 bits; conditional E-value: 7.5 EF_EFCAB10_C 10 LDptgrGyItl 20 +Dp ++Gy+++ FUN_001423-T1 504 IDPYNKGYVSY 514 5********97 PP == domain 6 score: 7.3 bits; conditional E-value: 0.0072 EF_EFCAB10_C 3 ldamFemLDptgrGyItlaQYkeALkTLGlstedev 38 l+ F +D++g G I+ + ++ +++LGl d + FUN_001423-T1 697 LRKTFVKFDSNGDGKISRKEFRMVMNSLGLYMTDDQ 732 56667778**********************887765 PP == domain 7 score: -0.6 bits; conditional E-value: 2 EF_EFCAB10_C 2 NldamFemLDptgrGyItlaQYkeALkTL 30 +l+a F+ +D +G++t ++ L ++ FUN_001423-T1 805 DLRAAFQKIDYDRNGFVTRPEFRRILDSF 833 78999*************99998877665 PP == domain 8 score: -1.6 bits; conditional E-value: 4.5 EF_EFCAB10_C 4 damFemLDptgrGyItla 21 + Fe D + GyI+ + FUN_001423-T1 1044 RKAFETVDANRDGYISRQ 1061 5679999********976 PP == domain 9 score: 0.5 bits; conditional E-value: 0.95 EF_EFCAB10_C 6 mFemLDptgrGyItlaQYk 24 F+ D+ ++G+++++Q + FUN_001423-T1 1402 SFRNTDSENKGVVNFEQLR 1420 566679***********87 PP == domain 10 score: 3.6 bits; conditional E-value: 0.1 EF_EFCAB10_C 6 mFemLDptgrGyItlaQYkeALk 28 F+ LD g G+ +l Q++e + FUN_001423-T1 1512 AFRALDKCGSGTCSLLQFREMMR 1534 6999***************9875 PP >> SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.9 6.4e+02 56 109 .. 119 174 .. 94 177 .. 0.54 2 ? -0.6 0.0 3.1 2.2e+03 62 81 .. 233 252 .. 196 274 .. 0.79 3 ? -0.9 0.0 3.9 2.8e+03 53 80 .. 346 373 .. 318 406 .. 0.69 4 ? -2.0 0.1 8.7 6.2e+03 56 82 .. 461 487 .. 434 518 .. 0.67 5 ! 13.8 0.0 0.00011 0.078 47 111 .. 560 625 .. 530 626 .. 0.78 6 ? 2.6 0.0 0.31 2.2e+02 52 80 .. 693 721 .. 649 727 .. 0.68 7 ? 4.9 0.0 0.062 44 39 111 .. 789 863 .. 767 865 .. 0.76 8 ? 7.1 0.4 0.013 9 19 111 .. 878 971 .. 872 972 .. 0.68 9 ! 7.7 0.1 0.0087 6.2 52 80 .. 1039 1067 .. 994 1101 .. 0.74 10 ? 0.9 0.2 1.1 7.8e+02 43 72 .. 1293 1322 .. 1219 1329 .. 0.66 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.9 SPARC_Ca_bdg 56 iawkFnklDtnkdklldksELaa.iraplvk.lEkCikpflescDankdkkislkE 109 + F+++D++k +++++sE + ++ ++ ++ ++++++ +n+d+++s E FUN_001423-T1 119 LRQAFQTFDSEKTHTITQSEFKRaLESFCIPlTDDQFEQLIRKVGTNRDGTVSYLE 174 44456666666666666666653133333331344455555666666666666555 PP == domain 2 score: -0.6 bits; conditional E-value: 3.1 SPARC_Ca_bdg 62 klDtnkdklldksELaaira 81 +D n+d+ ++++EL+ + + FUN_001423-T1 233 LFDYNRDGKIQRHELRRVIE 252 56888888888888887765 PP == domain 3 score: -0.9 bits; conditional E-value: 3.9 SPARC_Ca_bdg 53 keaiawkFnklDtnkdklldksELaair 80 + i F +Dt d++++ EL+ + FUN_001423-T1 346 HGNISRAFVAFDTRGDGFVTLDELKRVL 373 4456778999999999999999999875 PP == domain 4 score: -2.0 bits; conditional E-value: 8.7 SPARC_Ca_bdg 56 iawkFnklDtnkdklldksELaairap 82 ++ F +D nkd+ ++k++ + + ++ FUN_001423-T1 461 VKQAFLVFDDNKDGRVTKRDFRRVLES 487 555677777777777777777766554 PP == domain 5 score: 13.8 bits; conditional E-value: 0.00011 SPARC_Ca_bdg 47 kelkeckeaiawkFnklDtnkdklldksELaaira..plvklEkCikpflescDankdkkislkEwc 111 k+++++ +aia + +Dt++d+++++sEL+++ + l + + + ++cD n d++i+ +E++ FUN_001423-T1 560 KITDNW-KAIASAYLGVDTDRDGSISRSELRQLLErfCLPVSDDHFDLMWSRCDENADGSIDFQEFL 625 444444.467778999***************99661145566777888899**************95 PP == domain 6 score: 2.6 bits; conditional E-value: 0.31 SPARC_Ca_bdg 52 ckeaiawkFnklDtnkdklldksELaair 80 + + F k+D+n d+ ++++E + + FUN_001423-T1 693 RSTDLRKTFVKFDSNGDGKISRKEFRMVM 721 44455556777777777777777776665 PP == domain 7 score: 4.9 bits; conditional E-value: 0.062 SPARC_Ca_bdg 39 eeekeaeekelkeckeaiawkFnklDtnkdklldksELaairap..lvklEkCikpflescDankdkkislkEwc 111 ++++ + +++l+e + + F+k+D ++++++++ E + i + ++ ++ ++++ + D +k +++ +E++ FUN_001423-T1 789 SAVEAKMKTKLRENFQDLRAAFQKIDYDRNGFVTRPEFRRILDSfmIMLSDEEFDKLMARLDIQKGARLNYREFL 863 344455555666667778899*******************98761145557778999999999999999999986 PP == domain 8 score: 7.1 bits; conditional E-value: 0.013 SPARC_Ca_bdg 19 WlknlleelkereeekeeleeeekeaeekelkeckeaiawkFnklDtnkdklldksELaai..raplvklEkCikpflescDankdkkislkEwc 111 Wl+ ++ ++++ + + +++ +++ e +e +a F +D + +++++k+EL+++ + + + + k++ ++ D+++++ ++ +E++ FUN_001423-T1 878 WLYSTHSFNETQDLTY-LTAAQADDVIKRKAWEQNEDLAKAFLAFDHDGNGIVTKKELRKVlyKYQIPLNKEEFKKLWDKYDTDRNGYVDHQEFL 971 5655554443333333.333344444444444556667779*****************9984322333444558999****************96 PP == domain 9 score: 7.7 bits; conditional E-value: 0.0087 SPARC_Ca_bdg 52 ckeaiawkFnklDtnkdklldksELaair 80 e++ F+++D+n+d++++++EL+++ FUN_001423-T1 1039 GYESLRKAFETVDANRDGYISRQELQKVL 1067 45677889*****************9985 PP == domain 10 score: 0.9 bits; conditional E-value: 1.1 SPARC_Ca_bdg 43 eaeekelkeckeaiawkFnklDtnkdklld 72 +e++ ++++++ + +n lD+n d+ +d FUN_001423-T1 1293 ILNEHAFRMTSDQFNHIWNLLDKNADGKVD 1322 345556666777777777777777777666 PP >> SF3A3 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.47 3.3e+02 28 40 .. 168 181 .. 155 202 .. 0.85 2 ? -1.3 0.0 5 3.6e+03 28 39 .. 276 289 .. 265 299 .. 0.71 3 ? 4.6 0.0 0.072 51 23 41 .. 397 412 .. 385 428 .. 0.74 4 ! 8.6 0.1 0.004 2.9 17 40 .. 493 523 .. 490 530 .. 0.75 5 ? 1.6 0.0 0.6 4.3e+02 28 40 .. 745 758 .. 739 770 .. 0.81 6 ? 1.3 0.0 0.73 5.2e+02 25 42 .. 852 870 .. 846 877 .. 0.79 7 ? -1.1 0.0 4.2 3e+03 25 40 .. 1091 1105 .. 1087 1111 .. 0.80 8 ? -2.2 0.0 9.6 6.8e+03 26 40 .. 1201 1216 .. 1194 1222 .. 0.74 9 ? 1.2 0.0 0.82 5.8e+02 25 40 .. 1314 1332 .. 1305 1340 .. 0.75 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.47 SF3A3 28 g.lsYlqYLssfdk 40 g +sYl++L+ +++ FUN_001423-T1 168 GtVSYLEFLDRYHH 181 379******99876 PP == domain 2 score: -1.3 bits; conditional E-value: 5 SF3A3 28 g..lsYlqYLssfd 39 g l+Y+++L+ + FUN_001423-T1 276 GqtLEYMDFLKRLG 289 26799*****9884 PP == domain 3 score: 4.6 bits; conditional E-value: 0.072 SF3A3 23 NlkksglsYlqYLssfdkf 41 N k ++Y+q+L++f+ FUN_001423-T1 397 NHK---IPYVQFLEKFEAP 412 333...9*********875 PP == domain 4 score: 8.6 bits; conditional E-value: 0.004 SF3A3 17 lheeYlNlkksg.......lsYlqYLssfdk 40 h+++ l+ + +sYl++L+ f++ FUN_001423-T1 493 SHQQFHELMAKIdpynkgyVSYLDFLDRFEQ 523 6999999995548999777777777777765 PP == domain 5 score: 1.6 bits; conditional E-value: 0.6 SF3A3 28 g.lsYlqYLssfdk 40 g lsY+++L++f++ FUN_001423-T1 745 GkLSYMEFLNNFQD 758 3599*******975 PP == domain 6 score: 1.3 bits; conditional E-value: 0.73 SF3A3 25 kksg.lsYlqYLssfdkfs 42 k++ l+Y ++L+ f++++ FUN_001423-T1 852 QKGArLNYREFLKRFQHVE 870 555589*********9985 PP == domain 7 score: -1.1 bits; conditional E-value: 4.2 SF3A3 25 kksg.lsYlqYLssfdk 40 k + lsY ++Ls f++ FUN_001423-T1 1091 K--NkLSYEKFLSAFQD 1105 3..569*******9975 PP == domain 8 score: -2.2 bits; conditional E-value: 9.6 SF3A3 26 ksg.lsYlqYLssfdk 40 ++g +sY ++ +sf+k FUN_001423-T1 1201 EGGfVSYEDFFNSFQK 1216 3348999999999987 PP == domain 9 score: 1.2 bits; conditional E-value: 0.82 SF3A3 25 kksg....lsYlqYLssfdk 40 k + ++Y ++L+ f+ FUN_001423-T1 1314 DK-NadgkVDYRDFLKRFST 1332 33.34779*********975 PP >> DUF5580 Family of unknown function (DUF5580) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.0 0.0064 4.5 24 84 .. 913 972 .. 904 978 .. 0.84 2 ? 5.6 0.0 0.033 23 22 84 .. 1040 1101 .. 1021 1107 .. 0.85 3 ? 5.7 0.0 0.029 21 22 79 .. 1396 1453 .. 1383 1467 .. 0.80 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0064 DUF5580 24 klqkelkildPissGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkgspelvnyeklll 84 l k + ++d G++ + +l +++ ++++Pl+ k l +++ + v ++++l+ FUN_001423-T1 913 DLAKAFLAFDHDGNGIVTKKELRKVLYKYQIPLNKEEFKKLWDKYDTDR-NGYVDHQEFLA 972 6777788899999*******************************97654.45677777665 PP == domain 2 score: 5.6 bits; conditional E-value: 0.033 DUF5580 22 ldklqkelkildPissGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkgspelvnyeklll 84 + l+k ++++d G++ + +l+++++ ++ l+ +++l++r +++ + ++yek+l FUN_001423-T1 1040 YESLRKAFETVDANRDGYISRQELQKVLFDFHYFLDDVQLNILLDRCGLSHKNK-LSYEKFLS 1101 578999****************************************87766655.68999886 PP == domain 3 score: 5.7 bits; conditional E-value: 0.029 DUF5580 22 ldklqkelkildPissGfllqsqlsrlflrhevPlqlPtvkllcqrfsrkgspelvny 79 +++qk ++ d G++ ql ++l+h++ l l + s++g+ +v FUN_001423-T1 1396 WQHIQKSFRNTDSENKGVVNFEQLRDILLKHDIELSPREFLSLWRKHSNEGKGGIVYK 1453 5789999****************************98888888888888888777654 PP >> GPHH Voltage-dependent L-type calcium channel, IQ-associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 2.3 1.6e+03 1 14 [. 262 275 .. 262 288 .. 0.79 2 ? 0.6 0.0 1.1 7.6e+02 2 22 .. 497 517 .. 489 523 .. 0.66 3 ? 2.5 0.0 0.27 1.9e+02 2 21 .. 604 623 .. 603 628 .. 0.86 4 ? 4.9 0.0 0.05 35 1 24 [. 949 972 .. 949 980 .. 0.86 5 ? 0.3 0.0 1.3 9.4e+02 6 27 .. 1158 1179 .. 1155 1181 .. 0.87 6 ? 6.0 0.0 0.021 15 1 24 [. 1305 1328 .. 1305 1332 .. 0.91 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 2.3 GPHH 1 eFvrvWaeyDPeAt 14 +F + W++yD + + FUN_001423-T1 262 QFDKLWSKYDMTRN 275 58999*****7655 PP == domain 2 score: 0.6 bits; conditional E-value: 1.1 GPHH 2 FvrvWaeyDPeAtgrikvqdl 22 F + a++DP +g++++ d FUN_001423-T1 497 FHELMAKIDPYNKGYVSYLDF 517 444446677777777777765 PP == domain 3 score: 2.5 bits; conditional E-value: 0.27 GPHH 2 FvrvWaeyDPeAtgrikvqd 21 F +W+ D +A g+i +q+ FUN_001423-T1 604 FDLMWSRCDENADGSIDFQE 623 6678************9987 PP == domain 4 score: 4.9 bits; conditional E-value: 0.05 GPHH 1 eFvrvWaeyDPeAtgrikvqdlve 24 eF++ W +yD +g++ +q+ + FUN_001423-T1 949 EFKKLWDKYDTDRNGYVDHQEFLA 972 8******************99765 PP == domain 5 score: 0.3 bits; conditional E-value: 1.3 GPHH 6 WaeyDPeAtgrikvqdlvellr 27 a +D +g+i+ +dl+++++ FUN_001423-T1 1158 FAAFDRYGNGLISKEDLHQIIN 1179 589***************9875 PP == domain 6 score: 6.0 bits; conditional E-value: 0.021 GPHH 1 eFvrvWaeyDPeAtgrikvqdlve 24 +F ++W D +A g + ++d ++ FUN_001423-T1 1305 QFNHIWNLLDKNADGKVDYRDFLK 1328 699*****************9876 PP >> EF-hand_STIM1 Stromal interaction molecule 1-like, EF-hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 2.3 1.6e+03 18 40 .. 456 478 .. 440 487 .. 0.80 2 ? 3.7 0.0 0.14 96 19 47 .. 564 592 .. 550 595 .. 0.80 3 ? 0.5 0.1 1.3 9.6e+02 29 42 .. 610 623 .. 604 633 .. 0.86 4 ? 1.2 0.0 0.81 5.7e+02 11 43 .. 794 826 .. 784 844 .. 0.79 5 ? 6.1 0.0 0.024 17 19 57 .. 946 984 .. 929 1015 .. 0.80 6 ? 1.6 0.0 0.58 4.1e+02 16 46 .. 1036 1066 .. 1024 1073 .. 0.82 7 ? 2.5 0.1 0.31 2.2e+02 17 41 .. 1300 1324 .. 1288 1331 .. 0.79 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 2.3 EF-hand_STIM1 18 lgleAikslHkqlDdDkdGsvdl 40 ++ ++k+ Dd kdG+v FUN_001423-T1 456 NSFSSVKQAFLVFDDNKDGRVTK 478 4888999999999******9975 PP == domain 2 score: 3.7 bits; conditional E-value: 0.14 EF-hand_STIM1 19 gleAikslHkqlDdDkdGsvdlsEsdeFl 47 +Ai+s +D D+dGs+ +sE ++ l FUN_001423-T1 564 NWKAIASAYLGVDTDRDGSISRSELRQLL 592 67899999999************977655 PP == domain 3 score: 0.5 bits; conditional E-value: 1.3 EF-hand_STIM1 29 qlDdDkdGsvdlsE 42 + D+ +dGs+d++E FUN_001423-T1 610 RCDENADGSIDFQE 623 679*********99 PP == domain 4 score: 1.2 bits; conditional E-value: 0.81 EF-hand_STIM1 11 ctaekdrlgleAikslHkqlDdDkdGsvdlsEs 43 +++k r ++ +++ +++D D++G v + E FUN_001423-T1 794 KMKTKLRENFQDLRAAFQKIDYDRNGFVTRPEF 826 44566677899999999**********998885 PP == domain 5 score: 6.1 bits; conditional E-value: 0.024 EF-hand_STIM1 19 gleAikslHkqlDdDkdGsvdlsEsdeFlreeLkyedda 57 e k+l + D D++G vd++E l e+k d + FUN_001423-T1 946 NKEEFKKLWDKYDTDRNGYVDHQEFLARLGGEMKPGDTH 984 56677899999*************888888888876655 PP == domain 6 score: 1.6 bits; conditional E-value: 0.58 EF-hand_STIM1 16 drlgleAikslHkqlDdDkdGsvdlsEsdeF 46 r g+e++++ + +D +dG + ++E ++ FUN_001423-T1 1036 FRDGYESLRKAFETVDANRDGYISRQELQKV 1066 4569*********************997765 PP == domain 7 score: 2.5 bits; conditional E-value: 0.31 EF-hand_STIM1 17 rlgleAikslHkqlDdDkdGsvdls 41 r+ + +++ + lD +dG+vd+ FUN_001423-T1 1300 RMTSDQFNHIWNLLDKNADGKVDYR 1324 56667788999************86 PP >> EFhand_Ca_insen Ca2+ insensitive EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.032 23 6 31 .. 117 143 .. 114 163 .. 0.87 2 ? -1.6 0.0 5.6 4e+03 20 36 .. 327 343 .. 322 348 .. 0.84 3 ? -2.3 0.0 9.4 6.7e+03 8 31 .. 349 373 .. 342 375 .. 0.83 4 ? -0.3 0.0 2.3 1.6e+03 4 31 .. 457 485 .. 455 518 .. 0.81 5 ? 3.3 0.1 0.16 1.2e+02 6 31 .. 804 830 .. 801 865 .. 0.85 6 ? 5.5 0.0 0.034 24 5 64 .. 911 971 .. 908 975 .. 0.79 7 ? 2.6 0.0 0.27 1.9e+02 5 32 .. 1040 1068 .. 1037 1103 .. 0.76 8 ? -2.4 0.0 10 7.1e+03 6 21 .. 1175 1190 .. 1170 1190 .. 0.88 9 ? -0.7 0.0 3 2.1e+03 7 37 .. 1398 1429 .. 1396 1459 .. 0.76 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.032 EFhand_Ca_insen 6 eqvleaFralaegKpY.vTeedLrreL 31 ++++aF+ ++K+ +T+++++r+L FUN_001423-T1 117 AELRQAFQTFDSEKTHtITQSEFKRAL 143 579*******9999554********98 PP == domain 2 score: -1.6 bits; conditional E-value: 5.6 EFhand_Ca_insen 20 pYvTeedLrreLtpeqa 36 p vT +dL+++L + ++ FUN_001423-T1 327 PVVTIMDLEQKLRKRML 343 679********998776 PP == domain 3 score: -2.3 bits; conditional E-value: 9.4 EFhand_Ca_insen 8 vleaFral.aegKpYvTeedLrreL 31 + aF a g +vT ++L+r L FUN_001423-T1 349 ISRAFVAFdTRGDGFVTLDELKRVL 373 67788888778889*******9977 PP == domain 4 score: -0.3 bits; conditional E-value: 2.3 EFhand_Ca_insen 4 saeqvleaFralaegK.pYvTeedLrreL 31 s v +aF ++K vT+ d+rr L FUN_001423-T1 457 SFSSVKQAFLVFDDNKdGRVTKRDFRRVL 485 6667999999999999678******9977 PP == domain 5 score: 3.3 bits; conditional E-value: 0.16 EFhand_Ca_insen 6 eqvleaFralaegK.pYvTeedLrreL 31 +++++aF+ + ++ +vT ++rr L FUN_001423-T1 804 QDLRAAFQKIDYDRnGFVTRPEFRRIL 830 57899*****777757*******9966 PP == domain 6 score: 5.5 bits; conditional E-value: 0.034 EFhand_Ca_insen 5 aeqvleaFral.aegKpYvTeedLrreLtpeqaeycikrMkpysgpkgdsvegayDYvsFl 64 e++ +aF a +g vT+++Lr+ L + q+ +++ k+ ++ +g D +Fl FUN_001423-T1 911 NEDLAKAFLAFdHDGNGIVTKKELRKVLYKYQIPLNKEEFKKLWDKYDTDRNGYVDHQEFL 971 58999******99999*************99998877777777777645555555777776 PP == domain 7 score: 2.6 bits; conditional E-value: 0.27 EFhand_Ca_insen 5 aeqvleaFral.aegKpYvTeedLrreLt 32 +e +++aF + a+ Y+ ++L++ L FUN_001423-T1 1040 YESLRKAFETVdANRDGYISRQELQKVLF 1068 7999*******555559*******98775 PP == domain 8 score: -2.4 bits; conditional E-value: 10 EFhand_Ca_insen 6 eqvleaFralaegKpY 21 q+++aF + ++K++ FUN_001423-T1 1175 HQIINAFCFIMSDKQF 1190 59*******9999987 PP == domain 9 score: -0.7 bits; conditional E-value: 3 EFhand_Ca_insen 7 qvleaFral.aegKpYvTeedLrreLtpeqae 37 + ++Fr +e+K v e Lr L++ +e FUN_001423-T1 1398 HIQKSFRNTdSENKGVVNFEQLRDILLKHDIE 1429 6889*****99999999999999999998776 PP >> BCNT Bucentaur or craniofacial development # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 5 3.6e+03 52 65 .. 279 292 .. 271 298 .. 0.78 2 ? 6.8 0.1 0.015 11 40 67 .. 503 527 .. 492 530 .. 0.76 3 ? 8.3 0.1 0.0051 3.6 41 61 .. 954 974 .. 945 978 .. 0.80 4 ? -0.1 0.1 2.2 1.6e+03 30 56 .. 1035 1062 .. 1021 1067 .. 0.82 5 ? -0.6 0.0 3.1 2.2e+03 46 66 .. 1315 1335 .. 1307 1339 .. 0.77 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 5 BCNT 52 lekqdFLqRvdarq 65 le +dFL+R ++ FUN_001423-T1 279 LEYMDFLKRLGVKA 292 7889*****98775 PP == domain 2 score: 6.8 bits; conditional E-value: 0.015 BCNT 40 eLethnkgkdgYlekqdFLqRvdarqee 67 +++ +nkg Y++ dFL+R ++r+ e FUN_001423-T1 503 KIDPYNKG---YVSYLDFLDRFEQRETE 527 45555555...**************988 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0051 BCNT 41 LethnkgkdgYlekqdFLqRv 61 +++ +++gY+++q+FL+R FUN_001423-T1 954 WDKYDTDRNGYVDHQEFLARL 974 567788999**********96 PP == domain 4 score: -0.1 bits; conditional E-value: 2.2 BCNT 30 sfkdk.egikeeLethnkgkdgYlekqd 56 +f+d e +++ et ++dgY+++q+ FUN_001423-T1 1035 RFRDGyESLRKAFETVDANRDGYISRQE 1062 566666778888888888999*****98 PP == domain 5 score: -0.6 bits; conditional E-value: 3.1 BCNT 46 kgkdgYlekqdFLqRvdarqe 66 k+ dg ++ dFL+R r++ FUN_001423-T1 1315 KNADGKVDYRDFLKRFSTRTD 1335 4445667889*****999976 PP >> EF-hand_10 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 1.1 7.7e+02 2 44 .. 99 140 .. 98 175 .. 0.73 2 ? 6.3 0.0 0.02 14 3 43 .. 584 624 .. 582 626 .. 0.93 3 ? 3.7 0.0 0.13 91 4 43 .. 931 970 .. 929 973 .. 0.92 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.1 EF-hand_10 2 msfkEvknlLrliNievddeYArkLFqkcDkSksgrLegeEie 44 +sf E+ +r+ i v+ r+ Fq+ D k+ ++ + E+ FUN_001423-T1 99 LSFIEIESRMRE-KIRVNSAELRQAFQTFDSEKTHTITQSEFK 140 566666665555.466666667788888888888888888874 PP == domain 2 score: 6.3 bits; conditional E-value: 0.02 EF-hand_10 3 sfkEvknlLrliNievddeYArkLFqkcDkSksgrLegeEi 43 s +E+++lL + v+d ++ +cD+ ++g+++ +E+ FUN_001423-T1 584 SRSELRQLLERFCLPVSDDHFDLMWSRCDENADGSIDFQEF 624 679*********************************98887 PP == domain 3 score: 3.7 bits; conditional E-value: 0.13 EF-hand_10 4 fkEvknlLrliNievddeYArkLFqkcDkSksgrLegeEi 43 kE+++ L i ++ e +kL+ k D+ ++g+ +++E+ FUN_001423-T1 931 KKELRKVLYKYQIPLNKEEFKKLWDKYDTDRNGYVDHQEF 970 58999999999999999999*******************8 PP >> PfUIS3 Plasmodium falciparum UIS3 membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.4 0.00036 0.26 47 96 .. 1033 1082 .. 990 1085 .. 0.84 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00036 PfUIS3 47 kdslvndyeylrkivqtldesrdvslskaqedkavldlkyflkkvyanyl 96 +d + + ye lrk +t+d +rd +s+ + +k ++d +yfl +v n l FUN_001423-T1 1033 RDRFRDGYESLRKAFETVDANRDGYISRQELQKVLFDFHYFLDDVQLNIL 1082 46667889***********************************9987765 PP >> RPN13_C UCH-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 7.5 5.3e+03 62 76 .. 114 128 .. 108 129 .. 0.89 2 ? 4.5 0.0 0.077 54 60 95 .. 132 167 .. 121 176 .. 0.88 3 ? 5.2 0.0 0.047 33 62 104 .. 821 858 .. 815 866 .. 0.84 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 7.5 RPN13_C 62 lrSPqfrqalsslsq 76 ++S+++rqa +++++ FUN_001423-T1 114 VNSAELRQAFQTFDS 128 89***********85 PP == domain 2 score: 4.5 bits; conditional E-value: 0.077 RPN13_C 60 etlrSPqfrqalsslsqALqsgqlgpvlsqlgLdee 95 +t++ ++f+ al+s+ L +q+++++++ g + + FUN_001423-T1 132 HTITQSEFKRALESFCIPLTDDQFEQLIRKVGTNRD 167 688999***********************9998876 PP == domain 3 score: 5.2 bits; conditional E-value: 0.047 RPN13_C 62 lrSPqfrqalsslsqALqsgqlgpvlsqlgLdeeavaaaakgg 104 ++ P+fr l+s+ L+ +++ ++++ l++++ a + FUN_001423-T1 821 VTRPEFRRILDSFMIMLSDEEFDKLMARLDIQKG-----ARLN 858 677****************************998.....4444 PP >> Wap1 Wap1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2.1 1.5e+03 98 145 .. 136 184 .. 126 207 .. 0.80 2 ? -1.4 0.1 2 1.5e+03 98 140 .. 244 288 .. 225 295 .. 0.82 3 ? 9.3 0.0 0.0011 0.82 100 145 .. 825 871 .. 810 908 .. 0.86 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.1 Wap1 98 dkrlpsslenfileLskqe..kipkktkkgsklvkLnYkdFlkktefktg 145 +++++ le+f ++L+ ++ ++ +k +++ +Y +Fl + +++ g FUN_001423-T1 136 QSEFKRALESFCIPLTDDQfeQLIRKV-GTNRDGTVSYLEFLDRYHHRGG 184 4458889999*****998864555555.89999999******99998766 PP == domain 2 score: -1.4 bits; conditional E-value: 2 Wap1 98 dkrlpsslenfileLskqe..kipkktkkgsklvkLnYkdFlkkt 140 ++l+ +enf +L+ ++ k+ +k + L Y dFlk++ FUN_001423-T1 244 RHELRRVIENFCFRLTDEQfdKLWSKYDMTRNGQTLEYMDFLKRL 288 4457788999*****99987788888888889999*******986 PP == domain 3 score: 9.3 bits; conditional E-value: 0.0011 Wap1 100 rlpsslenfileLskqe..kipkktkkgsklvkLnYkdFlkktefktg 145 +++ l++f++ Ls +e k+ + +++k ++LnY +Flk++++ ++ FUN_001423-T1 825 EFRRILDSFMIMLSDEEfdKLMA-RLDIQKGARLNYREFLKRFQHVET 871 56778999*******99744444.449****************98765 PP >> W02B3_4_N W02B3.4-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 8.6 6.1e+03 72 105 .. 123 156 .. 112 160 .. 0.80 2 ? 10.8 0.2 0.00066 0.46 67 110 .. 913 956 .. 898 958 .. 0.90 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 8.6 W02B3_4_N 72 yleFktepkriipknfetrsignleiPsdikrFl 105 + F++e+++ i ++ r ++ + iP +F FUN_001423-T1 123 FQTFDSEKTHTITQSEFKRALESFCIPLTDDQFE 156 7789999999999975568899999998888875 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00066 W02B3_4_N 67 stskDyleFktepkriipknfetrsignleiPsdikrFlefWkr 110 + k +l F+++ + i+ k+ ++++ + +iP + ++F++ W + FUN_001423-T1 913 DLAKAFLAFDHDGNGIVTKKELRKVLYKYQIPLNKEEFKKLWDK 956 55688**************9888999****************75 PP >> HycA_repressor Transcriptional repressor of hyc and hyp operons # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.63 4.5e+02 54 131 .. 189 267 .. 176 280 .. 0.77 2 ? 1.5 0.0 0.71 5.1e+02 92 124 .. 461 493 .. 452 506 .. 0.86 3 ? 3.7 0.0 0.15 1e+02 76 124 .. 552 600 .. 542 619 .. 0.82 4 ? -1.9 0.0 7.8 5.5e+03 81 119 .. 903 941 .. 897 959 .. 0.85 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.63 HycA_repressor 54 lcfvlfehfrvfvalaegfnshvieyyvetkngedkvliaqaklaldgtldgkidnrdreqvlehylekia.tvydsly 131 l+f+ h +g + ie + +k g++ + + +a d dgki+ + +v+e + +++ +d+l+ FUN_001423-T1 189 LRFLGNLHRFNQTKSPKGVALDDIEDQLRKKMGGQLQSVMKALRLFDYNRDGKIQRHELRRVIENFCFRLTdEQFDKLW 267 5555544444445556788888899999***********************************9987665414566665 PP == domain 2 score: 1.5 bits; conditional E-value: 0.71 HycA_repressor 92 iaqaklaldgtldgkidnrdreqvlehylekia 124 + qa l d dg++ +rd +vle + +++ FUN_001423-T1 461 VKQAFLVFDDNKDGRVTKRDFRRVLESFCFRMS 493 679999********************9876655 PP == domain 3 score: 3.7 bits; conditional E-value: 0.15 HycA_repressor 76 vieyyvetkngedkvliaqaklaldgtldgkidnrdreqvlehylekia 124 ++e +++k ++ + ia a l +d dg+i+ + q+le + ++ FUN_001423-T1 552 TVEDILQSKITDNWKAIASAYLGVDTDRDGSISRSELRQLLERFCLPVS 600 78888899999999****************************9865554 PP == domain 4 score: -1.9 bits; conditional E-value: 7.8 HycA_repressor 81 vetkngedkvliaqaklaldgtldgkidnrdreqvlehy 119 ++ k e+ +a+a la d +g + +++ +vl +y FUN_001423-T1 903 IKRKAWEQNEDLAKAFLAFDHDGNGIVTKKELRKVLYKY 941 677888999999999999999999999999999999887 PP >> HSCB_C HSCB C-terminal oligomerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 0.15 1.1e+02 28 56 .. 103 131 .. 97 137 .. 0.84 2 ? 4.4 0.1 0.098 70 22 54 .. 784 816 .. 778 818 .. 0.86 3 ? -1.3 0.0 6 4.2e+03 28 52 .. 1027 1051 .. 1024 1058 .. 0.82 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.15 HSCB_C 28 elkkenkerikeleekleeafkek.dleaA 56 e++++++e+i+ +++l++af + d e+ FUN_001423-T1 103 EIESRMREKIRVNSAELRQAF-QTfDSEKT 131 799******************.66676665 PP == domain 2 score: 4.4 bits; conditional E-value: 0.098 HSCB_C 22 deeeleelkkenkerikeleekleeafkek.dle 54 d+ + ++++++k++++e ++l++af +k d++ FUN_001423-T1 784 DSMKASAVEAKMKTKLRENFQDLRAAF-QKiDYD 816 566778999******************.777998 PP == domain 3 score: -1.3 bits; conditional E-value: 6 HSCB_C 28 elkkenkerikeleekleeafkek.d 52 e+++++++r ++ e+l++af e d FUN_001423-T1 1027 EVEQRLRDRFRDGYESLRKAF-ETvD 1051 67899999*************.5334 PP >> ORF6N ORF6N domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.1 1.9 1.4e+03 37 62 .. 140 165 .. 118 177 .. 0.81 2 ? 9.1 0.2 0.003 2.1 36 66 .. 247 277 .. 241 287 .. 0.82 3 ? 1.7 0.1 0.63 4.5e+02 33 60 .. 478 505 .. 474 517 .. 0.85 4 ? 3.5 0.1 0.17 1.2e+02 38 63 .. 828 853 .. 814 868 .. 0.82 5 ? -1.2 0.1 4.9 3.5e+03 40 63 .. 1178 1201 .. 1171 1217 .. 0.81 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1.9 ORF6N 37 kRFpedfmfqLtkeelkelrsqfats 62 kR e+f++ Lt++++++l ++ t+ FUN_001423-T1 140 KRALESFCIPLTDDQFEQLIRKVGTN 165 566688***********999888886 PP == domain 2 score: 9.1 bits; conditional E-value: 0.003 ORF6N 36 kkRFpedfmfqLtkeelkelrsqfatsekkg 66 +R +e+f+f+Lt+e++++l s+ +++++ + FUN_001423-T1 247 LRRVIENFCFRLTDEQFDKLWSKYDMTRNGQ 277 57999*****************999986544 PP == domain 3 score: 1.7 bits; conditional E-value: 0.63 ORF6N 33 krNkkRFpedfmfqLtkeelkelrsqfa 60 kr +R e+f+f+++++++ el+ +++ FUN_001423-T1 478 KRDFRRVLESFCFRMSHQQFHELMAKID 505 77788999*************9998875 PP == domain 4 score: 3.5 bits; conditional E-value: 0.17 ORF6N 38 RFpedfmfqLtkeelkelrsqfatse 63 R ++fm+ L++ee+++l+ ++++++ FUN_001423-T1 828 RILDSFMIMLSDEEFDKLMARLDIQK 853 55567***********9999998863 PP == domain 5 score: -1.2 bits; conditional E-value: 4.9 ORF6N 40 pedfmfqLtkeelkelrsqfatse 63 ++ f+f +++++++ l ++++se FUN_001423-T1 1178 INAFCFIMSDKQFQALLKKIKISE 1201 566*************99999974 PP >> Caleosin Caleosin related protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 4.5 3.2e+03 91 120 .. 115 144 .. 110 148 .. 0.83 2 ? -2.1 0.0 6.4 4.5e+03 11 27 .. 232 248 .. 225 259 .. 0.71 3 ? 3.0 0.1 0.18 1.3e+02 89 118 .. 257 287 .. 253 300 .. 0.80 4 ? 0.4 0.1 1.1 7.9e+02 7 31 .. 462 486 .. 456 523 .. 0.77 5 ? 0.3 0.0 1.1 8e+02 3 35 .. 694 726 .. 692 737 .. 0.81 6 ? 2.4 0.1 0.27 1.9e+02 92 155 .. 839 906 .. 836 913 .. 0.86 7 ? -1.4 0.0 3.8 2.7e+03 11 28 .. 919 936 .. 909 946 .. 0.72 8 ? 6.9 0.0 0.011 7.9 90 137 .. 945 992 .. 935 999 .. 0.89 9 ? -1.2 0.1 3.3 2.3e+03 89 124 .. 1300 1335 .. 1295 1343 .. 0.81 10 ? -0.8 0.0 2.6 1.8e+03 90 122 .. 1430 1462 .. 1425 1468 .. 0.84 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 4.5 Caleosin 91 vpqkfeeiFskyaktekdaltlkellemlk 120 + +++ + F+ +++++++++t +e+++ l+ FUN_001423-T1 115 NSAELRQAFQTFDSEKTHTITQSEFKRALE 144 567788999999999999999999998775 PP == domain 2 score: -2.1 bits; conditional E-value: 6.4 Caleosin 11 aFfDrdkdGiiypldty 27 fD ++dG i ++ FUN_001423-T1 232 RLFDYNRDGKIQRHELR 248 56888888888777654 PP == domain 3 score: 3.0 bits; conditional E-value: 0.18 Caleosin 89 rfvpqkfeeiFskyaktek.daltlkellem 118 r++ ++f++++sky+ t++ ++l+++++l+ FUN_001423-T1 257 RLTDEQFDKLWSKYDMTRNgQTLEYMDFLKR 287 56789**********9965378888887765 PP == domain 4 score: 0.4 bits; conditional E-value: 1.1 Caleosin 7 qqHvaFfDrdkdGiiypldtykgfr 31 +q fD +kdG ++ d + + FUN_001423-T1 462 KQAFLVFDDNKDGRVTKRDFRRVLE 486 5556668888888888877655544 PP == domain 5 score: 0.3 bits; conditional E-value: 1.1 Caleosin 3 ktvLqqHvaFfDrdkdGiiypldtykgfralgf 35 +t L++ fD+++dG i + + +lg+ FUN_001423-T1 694 STDLRKTFVKFDSNGDGKISRKEFRMVMNSLGL 726 577777778899999999999988877777776 PP == domain 6 score: 2.4 bits; conditional E-value: 0.27 Caleosin 92 pqkfeeiFskyaktekdaltlkellemlkgnrealDlfgwlaallewl....alylllkdedgllske 155 ++f+++ ++ + ++ l+++e+l+ +++ +++ D wl ++ ++ ++yl + ++d+++++ FUN_001423-T1 839 DEEFDKLMARLDIQKGARLNYREFLKRFQHVETVEDGHPWLYSTHSFNetqdLTYLTAAQADDVIKRK 906 689*************************************9998888633336799999999998876 PP == domain 7 score: -1.4 bits; conditional E-value: 3.8 Caleosin 11 aFfDrdkdGiiypldtyk 28 fD+d++Gi++ + k FUN_001423-T1 919 LAFDHDGNGIVTKKELRK 936 558999999998887655 PP == domain 8 score: 6.9 bits; conditional E-value: 0.011 Caleosin 90 fvpqkfeeiFskyaktekdaltlkellemlkgnrealDlfgwlaalle 137 +++++f ++++ky+++++++++ +e+l+ l g++++ D+ g ++ ++e FUN_001423-T1 945 LNKEEFKKLWDKYDTDRNGYVDHQEFLARLGGEMKPGDTHGPSTMITE 992 57899**********************************998877766 PP == domain 9 score: -1.2 bits; conditional E-value: 3.3 Caleosin 89 rfvpqkfeeiFskyaktekdaltlkellemlkgnre 124 r++ ++f++i++ +k+ +++++++++l+ ++++ + FUN_001423-T1 1300 RMTSDQFNHIWNLLDKNADGKVDYRDFLKRFSTRTD 1335 677899999999999999999999999887776665 PP == domain 10 score: -0.8 bits; conditional E-value: 2.6 Caleosin 90 fvpqkfeeiFskyaktekdaltlkellemlkgn 122 + p++f ++++k++++ k+++ +k++++ + n FUN_001423-T1 1430 LSPREFLSLWRKHSNEGKGGIVYKDFMRHFVLN 1462 5789999******************99876655 PP >> EF-hand_14 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.0087 6.2 6 47 .. 123 164 .. 120 180 .. 0.90 2 ? -0.8 0.0 4 2.8e+03 7 39 .. 702 734 .. 699 757 .. 0.82 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0087 EF-hand_14 6 fdlfkdeetdklslakllkaLaetGirkdDPRlaellkklkk 47 f++f++e+t+++ +++ +aL+++ i +D ++l++k+ FUN_001423-T1 123 FQTFDSEKTHTITQSEFKRALESFCIPLTDDQFEQLIRKVGT 164 999**********************************99865 PP == domain 2 score: -0.8 bits; conditional E-value: 4 EF-hand_14 7 dlfkdeetdklslakllkaLaetGirkdDPRla 39 f+++ +k+s +++ +++ G+ +D + FUN_001423-T1 702 VKFDSNGDGKISRKEFRMVMNSLGLYMTDDQFR 734 568889999****************99886555 PP >> DUF5580_C Family of unknown function (DUF5580) C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.027 19 10 38 .. 227 255 .. 222 272 .. 0.90 2 ? -1.4 0.0 5.1 3.6e+03 5 38 .. 801 834 .. 799 856 .. 0.84 3 ? -0.9 0.0 3.6 2.6e+03 9 38 .. 913 942 .. 908 947 .. 0.85 4 ? -2.1 0.0 8.1 5.8e+03 5 37 .. 1038 1070 .. 1023 1075 .. 0.72 5 ? 2.4 0.1 0.34 2.4e+02 5 47 .. 1394 1432 .. 1390 1444 .. 0.80 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.027 DUF5580_C 10 lenalylcdlsntGvlekerarrlihnyn 38 + +al+l d + G ++++ rr+i n+ FUN_001423-T1 227 VMKALRLFDYNRDGKIQRHELRRVIENFC 255 679***********************985 PP == domain 2 score: -1.4 bits; conditional E-value: 5.1 DUF5580_C 5 drfrklenalylcdlsntGvlekerarrlihnyn 38 + f+ l a++ d + G + + rr++ + FUN_001423-T1 801 ENFQDLRAAFQKIDYDRNGFVTRPEFRRILDSFM 834 579999999***************9999998764 PP == domain 3 score: -0.9 bits; conditional E-value: 3.6 DUF5580_C 9 klenalylcdlsntGvlekerarrlihnyn 38 l +a+ d + G++ k+ r++++ y FUN_001423-T1 913 DLAKAFLAFDHDGNGIVTKKELRKVLYKYQ 942 577888889999**************9997 PP == domain 4 score: -2.1 bits; conditional E-value: 8.1 DUF5580_C 5 drfrklenalylcdlsntGvlekerarrlihny 37 d ++ l +a+ d + G + ++ ++++ ++ FUN_001423-T1 1038 DGYESLRKAFETVDANRDGYISRQELQKVLFDF 1070 445568888888888888888888777776665 PP == domain 5 score: 2.4 bits; conditional E-value: 0.34 DUF5580_C 5 drfrklenalylcdlsntGvlekerarrlihnynliynlslsP 47 r+++++++++ d++n Gv++ e+ r ++ +++ lsP FUN_001423-T1 1394 RRWQHIQKSFRNTDSENKGVVNFEQLRDILL----KHDIELSP 1432 6899999*****************9998763....34455555 PP >> HEF_HK HEF_HK domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.08 57 31 52 .. 793 814 .. 783 820 .. 0.85 2 ? 2.0 0.0 0.59 4.2e+02 25 54 .. 1024 1053 .. 1017 1055 .. 0.85 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.08 HEF_HK 31 adrnpklaklykelranFehLd 52 a++++kl++++++lra+F+++d FUN_001423-T1 793 AKMKTKLRENFQDLRAAFQKID 814 78899***************99 PP == domain 2 score: 2.0 bits; conditional E-value: 0.59 HEF_HK 25 rrLkpwadrnpklaklykelranFehLdgy 54 +L+ ++ +++++ y++lr++Fe d++ FUN_001423-T1 1024 SALEVEQRLRDRFRDGYESLRKAFETVDAN 1053 5677778889999************99975 PP >> DUF7874 Family of unknown function (DUF7874) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.055 39 42 75 .. 113 145 .. 103 155 .. 0.84 2 ? -0.6 0.0 2.6 1.8e+03 47 77 .. 459 489 .. 454 499 .. 0.82 3 ? -0.0 0.0 1.7 1.2e+03 46 75 .. 694 723 .. 682 729 .. 0.86 4 ? 1.3 0.0 0.66 4.7e+02 46 77 .. 803 834 .. 790 846 .. 0.83 5 ? -1.9 0.1 6.7 4.7e+03 42 72 .. 942 953 .. 910 971 .. 0.59 6 ? -1.6 0.0 5.4 3.8e+03 47 73 .. 1041 1067 .. 1039 1070 .. 0.89 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.055 DUF7874 42 rvpkkeeLeeayekhhkkkgkkltkeefqkilke 75 rv ++eL++a+++ ++k++++t+ ef++ l++ FUN_001423-T1 113 RVN-SAELRQAFQTFDSEKTHTITQSEFKRALES 145 554.568**********************98875 PP == domain 2 score: -0.6 bits; conditional E-value: 2.6 DUF7874 47 eeLeeayekhhkkkgkkltkeefqkilkevi 77 +++++a+ ++k+ ++tk +f+++l++ FUN_001423-T1 459 SSVKQAFLVFDDNKDGRVTKRDFRRVLESFC 489 5788999999999999**********98765 PP == domain 3 score: -0.0 bits; conditional E-value: 1.7 DUF7874 46 keeLeeayekhhkkkgkkltkeefqkilke 75 +++L++++ k ++ + k++++ef+ ++++ FUN_001423-T1 694 STDLRKTFVKFDSNGDGKISRKEFRMVMNS 723 5789******99777779*******99876 PP == domain 4 score: 1.3 bits; conditional E-value: 0.66 DUF7874 46 keeLeeayekhhkkkgkkltkeefqkilkevi 77 ++L+ a++k +++ +t+ ef++il + + FUN_001423-T1 803 FQDLRAAFQKIDYDRNGFVTRPEFRRILDSFM 834 47899*******888889*********98765 PP == domain 5 score: -1.9 bits; conditional E-value: 6.7 DUF7874 42 rvpkkeeLeeayekhhkkkgkkltkeefqki 72 + l+keef+k+ FUN_001423-T1 942 Q-------------------IPLNKEEFKKL 953 2...................24555555554 PP == domain 6 score: -1.6 bits; conditional E-value: 5.4 DUF7874 47 eeLeeayekhhkkkgkkltkeefqkil 73 e+L++a+e++ ++++ ++++e qk+l FUN_001423-T1 1041 ESLRKAFETVDANRDGYISRQELQKVL 1067 689********99999********997 PP >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 4.6 3.2e+03 94 119 .. 258 282 .. 242 291 .. 0.60 2 ? 2.5 0.0 0.24 1.7e+02 89 123 .. 471 505 .. 456 507 .. 0.90 3 ? -1.6 0.0 4.5 3.2e+03 94 105 .. 945 956 .. 923 967 .. 0.49 4 ? -1.0 0.0 3.1 2.2e+03 88 127 .. 1052 1091 .. 1040 1100 .. 0.64 5 ? -0.4 0.0 1.9 1.4e+03 91 123 .. 1166 1198 .. 1161 1201 .. 0.72 6 ? -0.4 0.0 1.9 1.4e+03 3 36 .. 1395 1429 .. 1393 1441 .. 0.73 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 4.6 COR-A 94 lkeedlkkiwkekypaeehdellrlm 119 l++e+++k+w++ y+ +++ + l+ m FUN_001423-T1 258 LTDEQFDKLWSK-YDMTRNGQTLEYM 282 556666666666.5555544444444 PP == domain 2 score: 2.5 bits; conditional E-value: 0.24 COR-A 89 kkkGllkeedlkkiwkekypaeehdellrlmekfe 123 +k+G+++++d+++++++ + h+++ +lm k + FUN_001423-T1 471 NKDGRVTKRDFRRVLESFCFRMSHQQFHELMAKID 505 566**************999***********9865 PP == domain 3 score: -1.6 bits; conditional E-value: 4.5 COR-A 94 lkeedlkkiwke 105 l++e++kk+w++ FUN_001423-T1 945 LNKEEFKKLWDK 956 344455555544 PP == domain 4 score: -1.0 bits; conditional E-value: 3.1 COR-A 88 lkkkGllkeedlkkiwkekypaeehdellrlmekfelcye 127 ++++G++++++l+k++ + + +l l+ ++ l+++ FUN_001423-T1 1052 ANRDGYISRQELQKVLFDFHYFLDDVQLNILLDRCGLSHK 1091 3445999999999988875444444455556666666666 PP == domain 5 score: -0.4 bits; conditional E-value: 1.9 COR-A 91 kGllkeedlkkiwkekypaeehdellrlmekfe 123 +Gl+++edl++i+++ +++ l++k + FUN_001423-T1 1166 NGLISKEDLHQIINAFCFIMSDKQFQALLKKIK 1198 79***********99754555555566666555 PP == domain 6 score: -0.4 bits; conditional E-value: 1.9 COR-A 3 swlevreelee.kkseknyisleeyreickenglk 36 +w ++++++++ ++k ++++e++r+i +++++ FUN_001423-T1 1395 RWQHIQKSFRNtDSENKGVVNFEQLRDILLKHDIE 1429 68888888888666677788888888888777775 PP >> SAPC2_N SAPC2 EF-hand like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 2 1.4e+03 9 38 .. 118 147 .. 114 177 .. 0.69 2 ? 0.7 0.1 1 7.1e+02 8 32 .. 459 483 .. 456 522 .. 0.77 3 ? 0.4 0.0 1.2 8.5e+02 10 33 .. 950 973 .. 947 987 .. 0.85 4 ? 3.5 0.0 0.13 89 8 32 .. 1041 1065 .. 1037 1104 .. 0.89 5 ? 0.0 0.1 1.6 1.1e+03 11 36 .. 1307 1332 .. 1303 1338 .. 0.85 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 2 SAPC2_N 9 slrtLFdilDdkktglvklsdiekrWqddg 38 lr+ F+ +D++kt ++ s+ ++ + FUN_001423-T1 118 ELRQAFQTFDSEKTHTITQSEFKRALESFC 147 69999************9999887665555 PP == domain 2 score: 0.7 bits; conditional E-value: 1 SAPC2_N 8 kslrtLFdilDdkktglvklsdiek 32 +s+++ F ++Dd+k+g v +d + FUN_001423-T1 459 SSVKQAFLVFDDNKDGRVTKRDFRR 483 688999**********999888765 PP == domain 3 score: 0.4 bits; conditional E-value: 1.2 SAPC2_N 10 lrtLFdilDdkktglvklsdiekr 33 +++L+d D +++g+v ++ +r FUN_001423-T1 950 FKKLWDKYDTDRNGYVDHQEFLAR 973 799*************99987665 PP == domain 4 score: 3.5 bits; conditional E-value: 0.13 SAPC2_N 8 kslrtLFdilDdkktglvklsdiek 32 +slr+ F+ +D +++g++ ++++k FUN_001423-T1 1041 ESLRKAFETVDANRDGYISRQELQK 1065 689****************999986 PP == domain 5 score: 0.0 bits; conditional E-value: 1.6 SAPC2_N 11 rtLFdilDdkktglvklsdiekrWqd 36 +++++lD++ +g v ++d kr+++ FUN_001423-T1 1307 NHIWNLLDKNADGKVDYRDFLKRFST 1332 56899**************9999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1571 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1216 (0.0476023); expected 510.9 (0.02) Passed bias filter: 914 (0.03578); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 38 (0.00148757); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 36 [number of targets reported over threshold] # CPU time: 0.58u 0.43s 00:00:01.01 Elapsed: 00:00:00.43 # Mc/sec: 14630.51 // Query: FUN_001424-T1 [L=180] Description: FUN_001424 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-19 68.5 0.2 1.1e-18 68.1 0.2 1.0 1 CYTH CYTH domain ------ inclusion threshold ------ 0.018 15.7 0.6 0.053 14.2 0.1 2.1 2 DUF4889 Domain of unknown function (DUF4889) 0.14 11.5 0.0 0.2 11.1 0.0 1.2 1 tRNA-synt_1f tRNA synthetases class I (K) Domain annotation for each model (and alignments): >> CYTH CYTH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.1 0.2 1.3e-22 1.1e-18 3 179 .] 4 163 .. 3 163 .. 0.85 Alignments for each domain: == domain 1 score: 68.1 bits; conditional E-value: 1.3e-22 CYTH 3 EiElKflvskeeakdlell.leklrakeekkeeqrdtYfdtpdrdlaktdeaLRiRrkngegae.lTlKgpkvdgereevegelsreEyeyllsdv 96 ++E+K++v+ ++ + ++ +++l a+e +++eqrd++f p+ ++L++R + + + + +++ + e+ ++s +y ++ FUN_001424-T1 4 NVEIKAKVE--DFVK-VVRkAKELSASEGEVIEQRDVFFIVPH-------GRLKLRYLQSRPSQvIFYERDD------EIGPKMS----NYHIATT 79 69******3..5444.4557**********************6.......7999997777777746666666......7777777....7777733 PP CYTH 97 edalelldglg..lkpvgsikkeRrrykvkgvevalDeveglegaevElElevedeeelkelaeellelarelglseeskvarfy 179 + +l d l+ l + g +kk+R y+v++++v+ Devegl g +vElE+ ++ + lke e + +l+++lg++e++ v+ +y FUN_001424-T1 80 DNPNSLMDVLScaLGQKGVVKKKRLLYLVGQTRVHCDEVEGL-GHFVELEVLMKENQSLKEGEEIAKDLMSKLGVKEADLVKGAY 163 3334577777788*****************************.************************************999877 PP >> DUF4889 Domain of unknown function (DUF4889) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 6.2e-06 0.053 25 63 .. 2 44 .. 1 48 [. 0.83 2 ? -1.8 0.0 0.6 5.1e+03 28 38 .. 149 159 .. 128 174 .. 0.60 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 6.2e-06 DUF4889 25 ekdadvkvkkgDfvilvkkedskkivkvkkvkhDD....vPhG 63 +++ ++k k +Dfv++v+k++ + ++ D vPhG FUN_001424-T1 2 PSNVEIKAKVEDFVKVVRKAKELSASEGEVIEQRDvffiVPHG 44 78899****************9999999999998844444888 PP == domain 2 score: -1.8 bits; conditional E-value: 0.6 DUF4889 28 advkvkkgDfv 38 + + vk D v FUN_001424-T1 149 SKLGVKEADLV 159 34445555544 PP >> tRNA-synt_1f tRNA synthetases class I (K) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 2.3e-05 0.2 276 333 .. 18 76 .. 11 90 .. 0.87 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 2.3e-05 tRNA-synt_1f 276 lkggekissSkGnvltledwlevaepevlrylilrskpkkakkldld.eilklvdeydk 333 +++ +++s S+G+v+ +d++ +++ l++ +l+s+p + + + d ei +++y+ FUN_001424-T1 18 VRKAKELSASEGEVIEQRDVFFIVPHGRLKLRYLQSRPSQVIFYERDdEIGPKMSNYHI 76 456669**********************************9999998899888888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (180 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 752 (0.0294382); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1760.97 // Query: FUN_001425-T1 [L=2362] Description: FUN_001425 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-25 89.2 0.0 5.1e-25 87.5 0.0 2.0 1 Tudor_KDM3B Lysine-specific demethylase 3B, tudor domain 2.9e-24 85.6 0.1 2.9e-24 85.6 0.1 2.8 3 PWWP_KDM3B Lysine-specific demethylase 3B, PWWP domain 5.8e-20 71.7 0.3 1.7e-19 70.2 0.3 1.9 1 DUF7030 Domain of unknown function (DUF7030) 4.6e-10 40.4 0.0 4.6e-10 40.4 0.0 3.6 4 JmjC JmjC domain, hydroxylase ------ inclusion threshold ------ 0.027 15.4 2.6 0.21 12.6 0.0 3.7 3 PWWP PWWP domain 0.08 13.2 0.0 0.2 11.9 0.0 1.7 1 Cupin_2 Cupin domain 0.53 10.9 7.8 4.5 7.9 7.8 2.7 1 FYVE FYVE zinc finger 0.94 10.3 6.6 3.2 8.7 6.6 1.9 1 C1_2 C1 domain Domain annotation for each model (and alignments): >> Tudor_KDM3B Lysine-specific demethylase 3B, tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.5 0.0 1.6e-28 5.1e-25 1 74 [. 183 257 .. 183 258 .. 0.94 Alignments for each domain: == domain 1 score: 87.5 bits; conditional E-value: 1.6e-28 Tudor_KDM3B 1 ilrkgpytlqGlrVkVYrpesetqWltavvsqhdevsrtlevtddqvleeqnvdPrlvqvtlldd..vvesllrge 74 il++gp+tl+G+rVkVYr+ ++qW++av+++hd +sr+l+v+dd+vl++++v+Prlvqv+ll + +++s+lrge FUN_001425-T1 183 ILLDGPFTLTGFRVKVYRQ-TCRQWFSAVITGHDLISRELSVMDDTVLQTHRVNPRLVQVMLLANepELDSVLRGE 257 899****************.99****************************************98855668888886 PP >> PWWP_KDM3B Lysine-specific demethylase 3B, PWWP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.6 0.1 9.1e-28 2.9e-24 1 96 [. 85 180 .. 85 181 .. 0.93 2 ? -4.0 0.8 8 2.6e+04 54 85 .. 555 586 .. 547 597 .. 0.58 3 ? -3.3 0.0 5 1.6e+04 37 66 .. 1829 1861 .. 1828 1864 .. 0.78 Alignments for each domain: == domain 1 score: 85.6 bits; conditional E-value: 9.1e-28 PWWP_KDM3B 1 fLvEqtlvwaerkdptseskestvlwPALvFrpLvdkvgl...gslvpveflgdrelefldkkslqpfqevdedslkpllreqpslqeavkawled 93 fLvE+t+vw++r dp+ ++ ++ lwPAL+F+pL+dk+gl ++ vpvef+gd+e+ f+++++++++ + d+d+l+p+lr++p++ +++++w+ + FUN_001425-T1 85 FLVEKTMVWSQRPDPS--NPRRPLLWPALTFSPLIDKHGLserEHPVPVEFVGDHERVFVRREECRSYGQ-DDDALQPILRNNPDVMKELRQWQLQ 177 9*************97..67789*****************988889**********************84.448********************99 PP PWWP_KDM3B 94 qkl 96 qk FUN_001425-T1 178 QKS 180 985 PP == domain 2 score: -4.0 bits; conditional E-value: 8 PWWP_KDM3B 54 lefldkkslqpfqevde.dslkpllreqpslqe 85 ++l++ ++q++q + +++++++++p qe FUN_001425-T1 555 QNLLHQYQMQCYQ-LQLiLQQQEIIQQKPLTQE 586 4555777777887.3233455555555554444 PP == domain 3 score: -3.3 bits; conditional E-value: 5 PWWP_KDM3B 37 kvgl..gslvpveflgdrelefl.dkkslqpfq 66 +v+l ++++ve +re e + ++k+ ++f FUN_001425-T1 1829 DVNLicDEITAVESTANREQEWVtEEKRRNHFT 1861 56666689999**99999999997777777775 PP >> DUF7030 Domain of unknown function (DUF7030) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.2 0.3 5.2e-23 1.7e-19 1 60 [] 8 74 .. 8 74 .. 0.82 Alignments for each domain: == domain 1 score: 70.2 bits; conditional E-value: 5.2e-23 DUF7030 1 elVGkRflcv....s...gseklklekise...weWraGviRAvshkdlsnpdlkvlVEFDdeewekreW 60 elVGkRfl+v s +s + +++s+ +eW GviR++s+kd+++p+lkvlVE+D+e+w++reW FUN_001425-T1 8 ELVGKRFLSVpeknSvrrNS---RSSRVSNpldYEWTTGVIRSCSEKDAHHPELKVLVEYDNEDWTTREW 74 79********8764222244...4444554555************************************* PP >> JmjC JmjC domain, hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.4 3.0 8 2.6e+04 52 83 .. 544 568 .. 523 606 .. 0.51 2 ? -2.6 0.0 3.4 1.1e+04 31 54 .. 919 942 .. 860 980 .. 0.60 3 ? -2.5 0.1 3.1 9.8e+03 8 53 .. 1249 1301 .. 1245 1349 .. 0.56 4 ! 40.4 0.0 1.5e-13 4.6e-10 14 114 .] 2199 2299 .. 2189 2299 .. 0.85 Alignments for each domain: == domain 1 score: -4.4 bits; conditional E-value: 8 JmjC 52 e.....nskeqpdllrhlstlispkqleeegipvyri 83 + ++++ ++l l + ++++y++ FUN_001425-T1 544 DflvnlWHQHYQNL------------LHQYQMQCYQL 568 22222244444444............33333333322 PP == domain 2 score: -2.6 bits; conditional E-value: 3.4 JmjC 31 pkvWyiipeekkeklekvlkkens 54 p+ + +e++e+l + ++k+n+ FUN_001425-T1 919 PCNTSRVASEASESLHSSVDKTNA 942 333344555555666666666644 PP == domain 3 score: -2.5 bits; conditional E-value: 3.1 JmjC 8 ksttpwhiedqglySinylhfgapkvWyiipeekkeklekvlkke.......n 53 +s ++ ++ed + +S +y+ ++ + ++ ++k + v++++ + FUN_001425-T1 1249 SSAKDGKLEDDSVFSKVYKMDNGKSSKMALKKLFQDKRKAVMSQNlpkglsnS 1301 56666666666666666666666666666666666666666666644443331 PP == domain 4 score: 40.4 bits; conditional E-value: 1.5e-13 JmjC 14 hiedqglySinylhfgapkvWyiipeekkeklekvlkkenskeqpdl.lrhlstlispkq.leeegipvyrivqkpgefVivfpgayHavfnlg 105 ++e+ + + ++++ a++ +i + ++ e+ +k ++ ++p++ + ++ + +++ e g++ + i q g+ V++++ga+H+v nl+ FUN_001425-T1 2199 RQETTRIG-ALWHIYAAEDADKIRDCLREIIKERKMKHSQ-HHDPIHdQCFYLDHDIRQRlKEDYGVEGWAICQCLGDSVFIPAGAPHQVRNLY 2290 55666666.7888888888888888888887888888885.799****99999998888867889***************************** PP JmjC 106 fniaeavnf 114 +++++a +f FUN_001425-T1 2291 SCVKVAEDF 2299 ******998 PP >> PWWP PWWP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 6.5e-05 0.21 13 66 .. 107 156 .. 103 177 .. 0.83 2 ? -2.0 0.0 2.4 7.6e+03 21 61 .. 574 612 .. 570 621 .. 0.62 3 ? -1.5 0.9 1.6 5.2e+03 49 88 .. 860 899 .. 803 907 .. 0.53 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 6.5e-05 PWWP 13 wWParvvdpeelpenvlkkkkkskklylVrFfgdseyawvkekdlkpfteeeek 66 WPa+ ++p ++ ++++++ ++V+F gd+e +v++++++++ +++++ FUN_001425-T1 107 LWPALTFSPLIDKHGLSEREHP----VPVEFVGDHERVFVRREECRSYGQDDDA 156 6********8888888777766....**********************887754 PP == domain 2 score: -2.0 bits; conditional E-value: 2.4 PWWP 21 peelpenvlkkkkkskklylVrFfgdseyawvkekdlkpft 61 ++e+ ++ +++++ ++lV+++++ +++ + ++l+++ FUN_001425-T1 574 QQEIIQQKPLTQEQR--NFLVEYYNQLLHQYQRAQNLQQLA 612 444444444444333..5*****997666777777777665 PP == domain 3 score: -1.5 bits; conditional E-value: 1.6 PWWP 49 yawvkekdlkpfteeeekeelkkkkkkkkkkafkkaveea 88 + vk ++ ++ +++++k+ + +++k++++f ++ ee+ FUN_001425-T1 860 QETVKGRKSTETKSKRQKKSKDAWSSRKDSRKFVASKEEI 899 3334333333333333333333333333333555554444 PP >> Cupin_2 Cupin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 6.2e-05 0.2 43 59 .. 2273 2289 .. 2272 2293 .. 0.94 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 6.2e-05 Cupin_2 43 GdsvyfpagvpHrfrNt 59 Gdsv++pag+pH++rN FUN_001425-T1 2273 GDSVFIPAGAPHQVRNL 2289 9**************96 PP >> FYVE FYVE zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 7.8 0.0014 4.5 9 52 .. 1654 1695 .. 1650 1710 .. 0.81 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0014 FYVE 9 keCseCkkeFtllrrrhHCrkCGkvfCskCsskkislleelkee 52 ++C+ C+++ ++ C++CG +C +C + +++ +e++ + FUN_001425-T1 1654 EMCDVCATTI--FNMHWVCHRCGFGVCLDCYNLRVKERQEQSGQ 1695 5799999876..688999***************99766555544 PP >> C1_2 C1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 6.6 0.00099 3.2 19 47 .. 1655 1681 .. 1649 1682 .. 0.92 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00099 C1_2 19 tCdaCgkkidgfesfYsCseCdfvlHerC 47 Cd+C+++i +++ C++C f ++ +C FUN_001425-T1 1655 MCDVCATTIFNMH--WVCHRCGFGVCLDC 1681 5********8888..************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2632 (0.103034); expected 510.9 (0.02) Passed bias filter: 529 (0.0207086); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.76u 0.40s 00:00:01.16 Elapsed: 00:00:00.44 # Mc/sec: 21510.94 // Query: FUN_001425-T2 [L=2034] Description: FUN_001425 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-25 89.4 0.1 4.3e-25 87.8 0.0 2.0 2 Tudor_KDM3B Lysine-specific demethylase 3B, tudor domain 2.4e-24 85.9 0.1 2.4e-24 85.9 0.1 2.9 3 PWWP_KDM3B Lysine-specific demethylase 3B, PWWP domain 4.8e-20 71.9 0.3 1.4e-19 70.4 0.3 1.9 1 DUF7030 Domain of unknown function (DUF7030) ------ inclusion threshold ------ 0.02 15.9 2.8 0.18 12.8 0.0 3.9 3 PWWP PWWP domain 0.55 10.8 7.8 3.8 8.2 7.8 2.5 1 FYVE FYVE zinc finger 0.94 10.3 6.6 2.7 8.9 6.6 1.8 1 C1_2 C1 domain 9.2 7.1 6.8 2.9 8.8 3.1 2.2 2 zf-C5HC2 C5HC2 zinc finger Domain annotation for each model (and alignments): >> Tudor_KDM3B Lysine-specific demethylase 3B, tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 4.8 1.7e+04 24 34 .. 39 49 .. 38 63 .. 0.72 2 ! 87.8 0.0 1.2e-28 4.3e-25 1 74 [. 183 257 .. 183 258 .. 0.94 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 4.8 Tudor_KDM3B 24 qWltavvsqhd 34 +W t+v+ + FUN_001425-T2 39 EWTTGVIRSCS 49 6*****97654 PP == domain 2 score: 87.8 bits; conditional E-value: 1.2e-28 Tudor_KDM3B 1 ilrkgpytlqGlrVkVYrpesetqWltavvsqhdevsrtlevtddqvleeqnvdPrlvqvtlldd..vvesllrge 74 il++gp+tl+G+rVkVYr+ ++qW++av+++hd +sr+l+v+dd+vl++++v+Prlvqv+ll + +++s+lrge FUN_001425-T2 183 ILLDGPFTLTGFRVKVYRQ-TCRQWFSAVITGHDLISRELSVMDDTVLQTHRVNPRLVQVMLLANepELDSVLRGE 257 899****************.99****************************************98855668888886 PP >> PWWP_KDM3B Lysine-specific demethylase 3B, PWWP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.9 0.1 6.7e-28 2.4e-24 1 96 [. 85 180 .. 85 181 .. 0.93 2 ? -3.7 0.7 5.8 2.1e+04 54 85 .. 555 586 .. 546 597 .. 0.58 3 ? -2.9 0.0 3.4 1.2e+04 37 66 .. 1829 1861 .. 1828 1865 .. 0.78 Alignments for each domain: == domain 1 score: 85.9 bits; conditional E-value: 6.7e-28 PWWP_KDM3B 1 fLvEqtlvwaerkdptseskestvlwPALvFrpLvdkvgl...gslvpveflgdrelefldkkslqpfqevdedslkpllreqpslqeavkawled 93 fLvE+t+vw++r dp+ ++ ++ lwPAL+F+pL+dk+gl ++ vpvef+gd+e+ f+++++++++ + d+d+l+p+lr++p++ +++++w+ + FUN_001425-T2 85 FLVEKTMVWSQRPDPS--NPRRPLLWPALTFSPLIDKHGLserEHPVPVEFVGDHERVFVRREECRSYGQ-DDDALQPILRNNPDVMKELRQWQLQ 177 9*************97..67789*****************988889**********************84.448********************99 PP PWWP_KDM3B 94 qkl 96 qk FUN_001425-T2 178 QKS 180 985 PP == domain 2 score: -3.7 bits; conditional E-value: 5.8 PWWP_KDM3B 54 lefldkkslqpfqevde.dslkpllreqpslqe 85 ++l++ ++q++q + +++++++++p qe FUN_001425-T2 555 QNLLHQYQMQCYQ-LQLiLQQQEIIQQKPLTQE 586 4556777788887.3233455555555554444 PP == domain 3 score: -2.9 bits; conditional E-value: 3.4 PWWP_KDM3B 37 kvgl..gslvpveflgdrelefl.dkkslqpfq 66 +v+l ++++ve +re e + ++k+ ++f FUN_001425-T2 1829 DVNLicDEITAVESTANREQEWVtEEKRRNHFT 1861 56666789999*******999997777777776 PP >> DUF7030 Domain of unknown function (DUF7030) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.4 0.3 3.8e-23 1.4e-19 1 60 [] 8 74 .. 8 74 .. 0.82 Alignments for each domain: == domain 1 score: 70.4 bits; conditional E-value: 3.8e-23 DUF7030 1 elVGkRflcv....s...gseklklekise...weWraGviRAvshkdlsnpdlkvlVEFDdeewekreW 60 elVGkRfl+v s +s + +++s+ +eW GviR++s+kd+++p+lkvlVE+D+e+w++reW FUN_001425-T2 8 ELVGKRFLSVpeknSvrrNS---RSSRVSNpldYEWTTGVIRSCSEKDAHHPELKVLVEYDNEDWTTREW 74 79********8764222244...4444554555************************************* PP >> PWWP PWWP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 4.8e-05 0.18 13 66 .. 107 156 .. 103 177 .. 0.83 2 ? -1.7 0.0 1.7 6.2e+03 21 61 .. 574 612 .. 570 622 .. 0.63 3 ? -1.3 0.9 1.2 4.4e+03 48 88 .. 859 899 .. 803 907 .. 0.53 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 4.8e-05 PWWP 13 wWParvvdpeelpenvlkkkkkskklylVrFfgdseyawvkekdlkpfteeeek 66 WPa+ ++p ++ ++++++ ++V+F gd+e +v++++++++ +++++ FUN_001425-T2 107 LWPALTFSPLIDKHGLSEREHP----VPVEFVGDHERVFVRREECRSYGQDDDA 156 6********8888888777766....**********************887754 PP == domain 2 score: -1.7 bits; conditional E-value: 1.7 PWWP 21 peelpenvlkkkkkskklylVrFfgdseyawvkekdlkpft 61 ++e+ ++ +++++ ++lV+++++ +++ + ++l+++ FUN_001425-T2 574 QQEIIQQKPLTQEQR--NFLVEYYNQLLHQYQRAQNLQQLA 612 444444444444333..5*****997666777777777765 PP == domain 3 score: -1.3 bits; conditional E-value: 1.2 PWWP 48 eyawvkekdlkpfteeeekeelkkkkkkkkkkafkkaveea 88 ++ vk ++ ++ +++++k+ + +++k++++f ++ ee+ FUN_001425-T2 859 KQETVKGRKSTETKSKRQKKSKDAWSSRKDSRKFVASKEEI 899 44334333333333333333333333333333555554444 PP >> FYVE FYVE zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 7.8 0.001 3.8 9 52 .. 1654 1695 .. 1650 1710 .. 0.81 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.001 FYVE 9 keCseCkkeFtllrrrhHCrkCGkvfCskCsskkislleelkee 52 ++C+ C+++ ++ C++CG +C +C + +++ +e++ + FUN_001425-T2 1654 EMCDVCATTI--FNMHWVCHRCGFGVCLDCYNLRVKERQEQSGQ 1695 5799999876..688999***************99766555544 PP >> C1_2 C1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 6.6 0.00074 2.7 19 47 .. 1655 1681 .. 1649 1682 .. 0.92 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00074 C1_2 19 tCdaCgkkidgfesfYsCseCdfvlHerC 47 Cd+C+++i +++ C++C f ++ +C FUN_001425-T2 1655 MCDVCATTIFNMH--WVCHRCGFGVCLDC 1681 5********8888..************** PP >> zf-C5HC2 C5HC2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.1 4.7 1.7e+04 8 18 .. 316 325 .. 314 329 .. 0.78 2 ? 8.8 3.1 0.0008 2.9 1 34 [. 1656 1688 .. 1656 1700 .. 0.87 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 4.7 zf-C5HC2 8 cYlSavkckkc 18 +YlS v+ c FUN_001425-T2 316 AYLSSVSST-C 325 7*****999.6 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0008 zf-C5HC2 1 CsiCkaycYlSavkckkcpgkvvCleHakelcsd 34 C++C ++ + + +c++c g vCl++++ +++ FUN_001425-T2 1656 CDVCATTIFNMHWVCHRC-GFGVCLDCYNLRVKE 1688 ******************.********9877763 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2034 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2967 (0.116148); expected 510.9 (0.02) Passed bias filter: 575 (0.0225093); expected 510.9 (0.02) Passed Vit filter: 88 (0.0034449); expected 25.5 (0.001) Passed Fwd filter: 20 (0.000782932); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.74u 0.39s 00:00:01.12 Elapsed: 00:00:00.43 # Mc/sec: 18914.89 // Query: FUN_001427-T1 [L=512] Description: FUN_001427 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-12 48.7 4.6 2.3e-12 48.0 4.6 1.4 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.033 14.6 0.1 0.083 13.3 0.1 1.7 1 Feld-I_B Allergen Fel d I-B chain 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain 0.12 13.3 0.2 0.34 11.9 0.0 1.8 2 CTD12 C-terminal domain 12 of the ABC-three component (AB 0.18 12.1 1.0 2.1 8.6 0.4 2.2 2 DUF4202 Domain of unknown function (DUF4202) Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.0 4.6 4.5e-16 2.3e-12 2 165 .. 109 269 .. 79 322 .. 0.83 Alignments for each domain: == domain 1 score: 48.0 bits; conditional E-value: 4.5e-16 MACPF 2 sfsassef.kklsqklkskkksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyi 92 s s+s+++ +++ +++ + +++ k+k+ + + +l+n e kL++ fl++ + Lp++++k+ k+ y kf+dk+G H+i sv+ G++i+++ FUN_001427-T1 109 SSSSSTAYsSNM--EVSGISLNILALKKKMFVKKECLTNVEISKLTKNFLDEYETLPKSISKPWKSHswqaYKKFLDKFGSHIILSVKDGARIKQT 202 678888995565..888888888888888888888888888899**************9887776667777**********************997 PP MACPF 93 l.kleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed 165 + ++++++ ++++ + + c+s+ +s+ g +++ +c n s+t++k +s+ +++++ +vlGGt+ + + FUN_001427-T1 203 TfAQSSESYSERDFQVKS---CVSLAGPTSV--GTLGVEACA-NISKTEKKRASN-MNTQKRLIVLGGTKNTRN 269 527788889999999988...9999999888..667776664.566666666666.9************94433 PP >> Feld-I_B Allergen Fel d I-B chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 1.6e-05 0.083 28 51 .. 47 71 .. 32 78 .. 0.83 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.6e-05 Feld-I_B 28 aTdeEkvAleKi.QDCynEeglkak 51 T++E + +eKi DC++E+ l++ FUN_001427-T1 47 FTEKEETVFEKIpDDCFKEKELHSS 71 59**********568*****99986 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 4.4e-05 0.23 34 74 .. 249 289 .. 235 295 .. 0.80 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.4e-05 GATase_3 34 deslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a + FUN_001427-T1 249 ASNMNTQKRLIVLGGTKNTRNALYSQRTKELIEKLMNEAGE 289 455567789**********************9999988765 PP >> CTD12 C-terminal domain 12 of the ABC-three component (ABC-3C) systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 6.6e-05 0.34 41 103 .. 138 197 .. 117 224 .. 0.80 2 ? -2.6 0.0 1.9 9.9e+03 84 96 .. 272 284 .. 238 327 .. 0.62 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 6.6e-05 CTD12 41 adkneinnlsaeyarailkkylkefaeveaflsaPenvelqqkyleivdelaakiiayrkdfe 103 +k+ + n+ ++k++l+e++++ + +s+P + q+y + d + + ii kd FUN_001427-T1 138 VKKECLTNVE---ISKLTKNFLDEYETLPKSISKPWKSHSWQAYKKFLDKFGSHIILSVKDGA 197 4554444442...4579***************************************9888755 PP == domain 2 score: -2.6 bits; conditional E-value: 1.9 CTD12 84 yleivdelaakii 96 y + +el k++ FUN_001427-T1 272 YSQRTKELIEKLM 284 2223333333332 PP >> DUF4202 Domain of unknown function (DUF4202) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.073 3.7e+02 22 51 .. 263 292 .. 240 317 .. 0.78 2 ? 8.6 0.4 0.00041 2.1 23 99 .. 407 487 .. 399 500 .. 0.84 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.073 DUF4202 22 gkelpkellyaqrmteylarlepeasealq 51 g+++ + ly+qr +e +++l ea+e q FUN_001427-T1 263 GTKNTRNALYSQRTKELIEKLMNEAGESDQ 292 455578899999999999999999998755 PP == domain 2 score: 8.6 bits; conditional E-value: 0.00041 DUF4202 23 kelpkellyaqrmteylarlepeasealqlAaraqhirR....wevprssypetragYlaWRtelkkrhAelaaellleag 99 + ++k +++a+r++++ + + ++ ++ ++ +h+ w++p ++ ++ gY + + + ++ + e +a++l+++ FUN_001427-T1 407 TGVSKITAHANRVESWSWHGCDWTQLWVRCGCKNKHLDQrkvvWTLPSRDFVKGSRGYDQHKPDAHEEQQESVASVLQKSA 487 3447778899999999999999999999********9644788*********************************98764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (512 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1287 (0.0503817); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4902.93 // Query: FUN_001428-T1 [L=512] Description: FUN_001428 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-12 48.7 4.6 2.3e-12 48.0 4.6 1.4 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.033 14.6 0.1 0.083 13.3 0.1 1.7 1 Feld-I_B Allergen Fel d I-B chain 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain 0.12 13.3 0.2 0.34 11.9 0.0 1.8 2 CTD12 C-terminal domain 12 of the ABC-three component (AB 0.18 12.1 1.0 2.1 8.6 0.4 2.2 2 DUF4202 Domain of unknown function (DUF4202) Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.0 4.6 4.5e-16 2.3e-12 2 165 .. 109 269 .. 79 322 .. 0.83 Alignments for each domain: == domain 1 score: 48.0 bits; conditional E-value: 4.5e-16 MACPF 2 sfsassef.kklsqklkskkksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyi 92 s s+s+++ +++ +++ + +++ k+k+ + + +l+n e kL++ fl++ + Lp++++k+ k+ y kf+dk+G H+i sv+ G++i+++ FUN_001428-T1 109 SSSSSTAYsSNM--EVSGISLNILALKKKMFVKKECLTNVEISKLTKNFLDEYETLPKSISKPWKSHswqaYKKFLDKFGSHIILSVKDGARIKQT 202 678888995565..888888888888888888888888888899**************9887776667777**********************997 PP MACPF 93 l.kleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed 165 + ++++++ ++++ + + c+s+ +s+ g +++ +c n s+t++k +s+ +++++ +vlGGt+ + + FUN_001428-T1 203 TfAQSSESYSERDFQVKS---CVSLAGPTSV--GTLGVEACA-NISKTEKKRASN-MNTQKRLIVLGGTKNTRN 269 527788889999999988...9999999888..667776664.566666666666.9************94433 PP >> Feld-I_B Allergen Fel d I-B chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 1.6e-05 0.083 28 51 .. 47 71 .. 32 78 .. 0.83 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.6e-05 Feld-I_B 28 aTdeEkvAleKi.QDCynEeglkak 51 T++E + +eKi DC++E+ l++ FUN_001428-T1 47 FTEKEETVFEKIpDDCFKEKELHSS 71 59**********568*****99986 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 4.4e-05 0.23 34 74 .. 249 289 .. 235 295 .. 0.80 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.4e-05 GATase_3 34 deslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a + FUN_001428-T1 249 ASNMNTQKRLIVLGGTKNTRNALYSQRTKELIEKLMNEAGE 289 455567789**********************9999988765 PP >> CTD12 C-terminal domain 12 of the ABC-three component (ABC-3C) systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 6.6e-05 0.34 41 103 .. 138 197 .. 117 224 .. 0.80 2 ? -2.6 0.0 1.9 9.9e+03 84 96 .. 272 284 .. 238 327 .. 0.62 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 6.6e-05 CTD12 41 adkneinnlsaeyarailkkylkefaeveaflsaPenvelqqkyleivdelaakiiayrkdfe 103 +k+ + n+ ++k++l+e++++ + +s+P + q+y + d + + ii kd FUN_001428-T1 138 VKKECLTNVE---ISKLTKNFLDEYETLPKSISKPWKSHSWQAYKKFLDKFGSHIILSVKDGA 197 4554444442...4579***************************************9888755 PP == domain 2 score: -2.6 bits; conditional E-value: 1.9 CTD12 84 yleivdelaakii 96 y + +el k++ FUN_001428-T1 272 YSQRTKELIEKLM 284 2223333333332 PP >> DUF4202 Domain of unknown function (DUF4202) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.073 3.7e+02 22 51 .. 263 292 .. 240 317 .. 0.78 2 ? 8.6 0.4 0.00041 2.1 23 99 .. 407 487 .. 399 500 .. 0.84 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.073 DUF4202 22 gkelpkellyaqrmteylarlepeasealq 51 g+++ + ly+qr +e +++l ea+e q FUN_001428-T1 263 GTKNTRNALYSQRTKELIEKLMNEAGESDQ 292 455578899999999999999999998755 PP == domain 2 score: 8.6 bits; conditional E-value: 0.00041 DUF4202 23 kelpkellyaqrmteylarlepeasealqlAaraqhirR....wevprssypetragYlaWRtelkkrhAelaaellleag 99 + ++k +++a+r++++ + + ++ ++ ++ +h+ w++p ++ ++ gY + + + ++ + e +a++l+++ FUN_001428-T1 407 TGVSKITAHANRVESWSWHGCDWTQLWVRCGCKNKHLDQrkvvWTLPSRDFVKGSRGYDQHKPDAHEEQQESVASVLQKSA 487 3447778899999999999999999999********9644788*********************************98764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (512 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1287 (0.0503817); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4873.53 // Query: FUN_001429-T1 [L=813] Description: FUN_001429 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-23 83.2 4.4 2.6e-12 47.8 0.2 2.3 2 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.024 14.7 0.2 0.43 10.7 0.1 2.2 2 GATase_3 CobB/CobQ-like glutamine amidotransferase dom 0.049 13.9 0.2 6.2 7.2 0.0 3.0 3 IF2_N Translation initiation factor IF-2, N-termina 0.18 12.1 0.2 4.8 7.6 0.1 2.5 2 EF-hand_EFHB_C EFHB C-terminal EF-hand domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.8 0.2 4.1e-16 2.6e-12 41 210 .. 145 318 .. 99 323 .. 0.79 2 ! 36.7 0.7 1e-12 6.5e-09 67 165 .. 475 570 .. 420 622 .. 0.79 Alignments for each domain: == domain 1 score: 47.8 bits; conditional E-value: 4.1e-16 MACPF 41 eklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkl.eksklekskskgedvkiclsaeakasikngkvslkg 131 e +L++++lk+ + Lp + ++ a y++f++++G Hvitsv+ G+ i++++ ++++ ++++ + + c+s+ +++ gk+++ + FUN_001429-T1 145 EISNLTKRLLKDFEILPLRFAEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAeSSESYSQRDFQIKS---CISLAGPTNV--GKLGVEA 235 3345999999999999999999888878999***********************99888355556666666666...9999999999..9****** PP MACPF 132 ckknssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAl 210 c + s+s+ ++ s +++ k +v+GGt ++ + +++e ++ +++ e ++++++++++ ++l++ ++ n+ +A+ FUN_001429-T1 236 CANVSNSEVSSAS--TMNTVDKLIVRGGTRETRNalfnqRTKELIEKLMNEAGESNAAVEHSFRSIWDILQSRFkYGSDNYIRAV 318 *999999888885..469999********97777999999999999999999999999999999999999887766777777776 PP == domain 2 score: 36.7 bits; conditional E-value: 1e-12 MACPF 67 t...yikfidkYGTHvitsvslGGkivyil.kleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlG 158 t +f+dk+G H+i s++ G+ i++++ ++++++ ++++ + + c+s+ +s+ g+v+++gc++ s+ +k+ ss+++++ k +vlG FUN_001429-T1 475 TwshSKQFLDKFGSHIILSIKSGASIKQTTfAQSSESYSERDFQIKS---CVSLAGPTSV--GEVGVDGCGNISKTEKN--RSSNMNTQGKLIVLG 563 0444579*******************997527788999999999999...****999999..99****99875554444..44669********** PP MACPF 159 Gtpdsed 165 Gt+ +++ FUN_001429-T1 564 GTKNTQN 570 **94433 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.039 2.5e+02 27 73 .. 239 286 .. 221 292 .. 0.66 2 ? 10.7 0.1 6.7e-05 0.43 34 74 .. 550 590 .. 540 596 .. 0.83 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.039 GATase_3 27 vrfvplkdeslgedad.lvilpGgkntlqdlallresglkeaikeaae 73 v ++++ s + +d l++ +G+++t+++l +r ++l e++ + a FUN_001429-T1 239 VSNSEVSSASTMNTVDkLIVRGGTRETRNALFNQRTKELIEKLMNEAG 286 344444444444556626666888889998888888888888887664 PP == domain 2 score: 10.7 bits; conditional E-value: 6.7e-05 GATase_3 34 deslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt ++l ++r ++l e++ + a + FUN_001429-T1 550 SSNMNTQGKLIVLGGTKNTQNALHSQRTKELIEKLMNEADE 590 455667789************************99998765 PP >> IF2_N Translation initiation factor IF-2, N-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.33 2.1e+03 7 24 .. 28 45 .. 28 47 .. 0.88 2 ? 7.2 0.0 0.00097 6.2 14 32 .. 271 290 .. 269 295 .. 0.82 3 ? 2.7 0.0 0.024 1.5e+02 16 30 .. 576 591 .. 573 598 .. 0.80 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.33 IF2_N 7 yeLAkelgvsskelikkL 24 yeLAk +++ + l++ + FUN_001429-T1 28 YELAKGVNLRKTNLLSDF 45 8********999999876 PP == domain 2 score: 7.2 bits; conditional E-value: 0.00097 IF2_N 14 gvsskelikkLfk.lGimvk 32 + ++keli+kL++ +G + + FUN_001429-T1 271 NQRTKELIEKLMNeAGESNA 290 6689************9865 PP == domain 3 score: 2.7 bits; conditional E-value: 0.024 IF2_N 16 sskelikkLfk.lGim 30 ++keli+kL++ ++ FUN_001429-T1 576 RTKELIEKLMNeADET 591 579*******988766 PP >> EF-hand_EFHB_C EFHB C-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.1 0.00075 4.8 19 52 .. 269 304 .. 265 311 .. 0.84 2 ? 1.6 0.0 0.052 3.3e+02 19 50 .. 572 605 .. 568 616 .. 0.75 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.00075 EF-hand_EFHB_C 19 ffkpRskeeirrifenigvk..lsdetFeeiWkeas 52 +f R+ke i+++++++g + + +F +iW+ + FUN_001429-T1 269 LFNQRTKELIEKLMNEAGESnaAVEHSFRSIWDILQ 304 7999**************996667889*****9766 PP == domain 2 score: 1.6 bits; conditional E-value: 0.052 EF-hand_EFHB_C 19 ffkpRskeeirrifenigvk..lsdetFeeiWke 50 + R+ke i++++++++ + tF +iW+ FUN_001429-T1 572 LHSQRTKELIEKLMNEADETdaAVAHTFPSIWDV 605 5678***********9977655666788888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (813 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1120 (0.0438442); expected 510.9 (0.02) Passed bias filter: 649 (0.0254061); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 7803.07 // Query: FUN_001430-T1 [L=492] Description: FUN_001430 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-12 48.5 0.1 2.4e-12 47.9 0.1 1.3 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.9 0.1 9.4e-17 2.4e-12 42 210 .. 149 321 .. 102 326 .. 0.79 Alignments for each domain: == domain 1 score: 47.9 bits; conditional E-value: 9.4e-17 MACPF 42 klkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkl.eksklekskskgedvkiclsaeakasikngkvslkgc 132 +L++++l++ + Lp + ++ a y++f++++G Hvitsv+ G+ i++++ ++++ ++++ + + c+s+ +++ +k+++ +c FUN_001430-T1 149 ISNLTKRLLRDFEILPLRFAEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAeSSESYSQRDFQIKS---CISLAGPTNV--DKLGVEAC 239 345899999999999999888887778889***********************99888355556666666666...9999999999..99****** PP MACPF 133 kknssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAl 210 + s+s+ ++ s +++ k +v+GGt ++ + +++e ++ +++ e ++++++++++ ++l++ ++ n+ +A+ FUN_001430-T1 240 ANVSNSEVTSAS--TMNTVDKLIVRGGTRETRNalfnqRTKELIEKLMNEAGESNAAVEHSFRSIWDILQSRFkYGSDNYIRAV 321 999999988885..469999********97777999999999999999999999999999999999999887766777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (492 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 918 (0.0359366); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.37s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 4823.21 // Query: FUN_001431-T1 [L=120] Description: FUN_001431 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0065 17.1 1.0 0.0077 16.9 1.0 1.1 1 MACPF MAC/Perforin domain 0.0089 16.1 0.0 0.012 15.7 0.0 1.2 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 1.0 6e-07 0.0077 90 164 .. 24 91 .. 16 112 .. 0.76 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 6e-07 MACPF 90 vyilkleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdse 164 + ++++++++ ++++ + + c+s++ +s+ g+v++k+c++ s+ +++ s+++++ k +vlGGt+ + FUN_001431-T1 24 QTTFAQSSESYSERDFQIKS---CVSLGGPTSV--GEVGVKACGNISETERNRV--SNMNTQGKLIVLGGTKNTR 91 34455588888888888888...*****99999..99****9997766666655..569************9432 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 9.5e-07 0.012 35 74 .. 73 112 .. 59 116 .. 0.82 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 9.5e-07 GATase_3 35 eslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a k FUN_001431-T1 73 SNMNTQGKLIVLGGTKNTRNALHSQRTKELFEKLMNEADK 112 44556789**************************998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 854 (0.0334312); expected 510.9 (0.02) Passed bias filter: 580 (0.022705); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1220.69 // Query: FUN_001432-T1 [L=509] Description: FUN_001432 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-11 43.5 3.3 5.8e-11 43.4 2.2 1.6 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.4 2.2 4.5e-15 5.8e-11 20 165 .. 123 266 .. 103 319 .. 0.79 Alignments for each domain: == domain 1 score: 43.4 bits; conditional E-value: 4.5e-15 MACPF 20 kksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyil.kleksklekskskgedv 110 + +++ k+k+ l + +l+n e kL++ fl++ +aLp++++k+ k+ y+k++dk+G H + s++ G+ i++++ ++++++ ++++ + + FUN_001432-T1 123 SLNILALKKKILLKKECLANVEISKLTKNFLDKYEALPKSINKPWKSHswqaYTKLLDKFGSHNMPSIKRGASIKQTTfAQSSESYSERDFQIKS- 217 4445555566666666666666678**************9888877777888**********************997527788999999999999. PP MACPF 111 kiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed 165 c+s++ +s+ g+v++k+c++ s+ +++ s+++++ k +vlGGt+ +++ FUN_001432-T1 218 --CVSLGGPTSV--GEVGVKACGNISETERNRV--SNMNTQGKLIVLGGTKNTQN 266 ..******9999..9******998766666655..569************94433 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 2.1e-05 0.27 35 74 .. 247 286 .. 235 292 .. 0.82 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.1e-05 GATase_3 35 eslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt ++l ++r ++l e++ + a + FUN_001432-T1 247 SNMNTQGKLIVLGGTKNTQNALHSQRTKELIEKLMNEADE 286 34556789************************99998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (509 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1175 (0.0459973); expected 510.9 (0.02) Passed bias filter: 646 (0.0252887); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 5119.25 // Query: FUN_001433-T1 [L=461] Description: FUN_001433 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-12 48.8 0.1 2e-12 48.2 0.1 1.3 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.2 0.1 7.8e-17 2e-12 44 210 .. 132 302 .. 83 307 .. 0.78 Alignments for each domain: == domain 1 score: 48.2 bits; conditional E-value: 7.8e-17 MACPF 44 kLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkl.eksklekskskgedvkiclsaeakasikngkvslkgckk 134 +L++++lk+ + Lp + ++ a y++f++++G Hvitsv+ G+ i++++ ++++ ++++ + + c+s+ +++ +k+++ +c + FUN_001433-T1 132 NLTKRLLKDFEILPLRFPEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAeSSESYSQRDFQIKS---CISLAGPTNV--DKLGVEACAN 222 4777777777777777766666667777***********************99888355556666666666...9999999999..99******99 PP MACPF 135 nssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAl 210 s+s+ ++ s +++ k +v+GGt ++ + +++e ++ +++ e ++++++++++ ++l++ ++ n+ +A+ FUN_001433-T1 223 VSNSEVTSAS--TMNTVDKLIVRGGTRETRNalfnqRTKELIEKLMNEAGESNAAVEHSFRSIWDILQSRFkYGSDNYIRAV 302 9999988885..469999********97777999999999999999999999999999999999999987766777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (461 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 811 (0.0317479); expected 510.9 (0.02) Passed bias filter: 522 (0.0204345); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4515.74 // Query: FUN_001434-T1 [L=509] Description: FUN_001434 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-13 52.1 2.4 2.4e-13 51.2 2.4 1.6 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.078 13.1 0.1 0.14 12.2 0.1 1.3 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.2 2.4 1.9e-17 2.4e-13 20 165 .. 123 266 .. 68 318 .. 0.80 Alignments for each domain: == domain 1 score: 51.2 bits; conditional E-value: 1.9e-17 MACPF 20 kksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyi.lkleksklekskskgedv 110 + +++ k+k+ l + +l+n e kL++ fl++ +aLp++++k+ k+ y+kf+dk+G H+i s++ G+ i+++ +++++++ ++++ + + FUN_001434-T1 123 SLNILALKKKILLKKECLANVEISKLTKNFLDEYEALPKSINKPWKSHswqaYTKFLDKFGSHIIPSIKSGASIKQKtFAQSSESYSERDFQIKS- 217 4444555566666666666666678**************9888877777888**********************986157899999999999999. PP MACPF 111 kiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed 165 c+s+ +s+ g+v++k+c++ s+ +k+ s+++++ k +vlGGt+ + + FUN_001434-T1 218 --CVSLAGPTSV--GEVGVKPCGNISKTEKNRA--SNMNTQGKLIVLGGTKNTRN 266 ..****999999..********97665555554..669************94433 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 1.1e-05 0.14 35 74 .. 247 286 .. 236 292 .. 0.83 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.1e-05 GATase_3 35 eslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a + FUN_001434-T1 247 SNMNTQGKLIVLGGTKNTRNALHSQRTKELIEKLMNEADE 286 55667789************************99998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (509 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1152 (0.0450969); expected 510.9 (0.02) Passed bias filter: 613 (0.0239969); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 4963.38 // Query: FUN_001435-T1 [L=215] Description: FUN_001435 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-06 29.3 0.0 1.8e-06 28.8 0.0 1.4 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 0.0 6.9e-11 1.8e-06 44 100 .. 136 196 .. 86 210 .. 0.73 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 6.9e-11 MACPF 44 kLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilklekskl 100 +L++++lk+ + Lp + ++ a y++f++++G Hvitsv+ G+ i++++ e+s+ FUN_001435-T1 136 NLTKRLLKDFEILPLRFPEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAESSES 196 4777777777777777766666667777************************997766553 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (215 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 534 (0.0209043); expected 510.9 (0.02) Passed bias filter: 408 (0.0159718); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2118.36 // Query: FUN_001436-T1 [L=131] Description: FUN_001436 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 993 (0.0388726); expected 510.9 (0.02) Passed bias filter: 416 (0.016285); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1304.37 // Query: FUN_001437-T1 [L=512] Description: FUN_001437 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-13 52.1 6.7 1.6e-13 51.8 6.1 1.5 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 Feld-I_B Allergen Fel d I-B chain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.8 6.1 1.8e-17 1.6e-13 2 210 .. 109 320 .. 106 326 .. 0.82 Alignments for each domain: == domain 1 score: 51.8 bits; conditional E-value: 1.8e-17 MACPF 2 sfsassef.kklsqklkskkksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyi 92 s s+s e+ +++ +++ + +++ k+k+ + + +l+n e kL++ fl++ +aLp++++k+ k+ y+kf+dk+G H+i s++ G+ i+++ FUN_001437-T1 109 SSSSSNEYsSNM--EVSGISLNILALKKKMFVKKECLTNVEISKLTKNFLDEYEALPKSINKPWKSHswqaYTKFLDKFGSHIILSIKSGSSIKQT 202 678888885555..888888888888888888888888888899**************9888877777888**********************997 PP MACPF 93 l.kleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenp 182 + ++++++ ++++ + + c+s+ +s+ gkv++++c++ s+ +k+ s+++++ k +vlGGt+ + + +++e +++ +++ e+ FUN_001437-T1 203 TfAQSSESYSERDFQIKS---CVSLAGPTSV--GKVGVDACGNISEIEKNRA--SNMNTQGKLIVLGGTKNTRNalhsqRTKELFEKLMNEADETD 291 527788999999999999...****999999..9*******97666555555..669************965558998888888888888888888 PP MACPF 183 dpIkfeltplsellkeep.kkkenlrqAl 210 +++ +++t++ + l++ + n+ +A+ FUN_001437-T1 292 AAVAHTFTSIWDVLRSRFkHGTDNYIRAV 320 88888888888888877655556666665 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 1.3e-05 0.11 34 74 .. 249 289 .. 237 295 .. 0.82 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.3e-05 GATase_3 34 deslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a + FUN_001437-T1 249 ASNMNTQGKLIVLGGTKNTRNALHSQRTKELFEKLMNEADE 289 455667899*************************9998765 PP >> Feld-I_B Allergen Fel d I-B chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 4.2e-05 0.36 25 49 .. 44 69 .. 31 76 .. 0.77 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 4.2e-05 Feld-I_B 25 lvnaTdeEkvAleKi.QDCynEeglk 49 l + T++E + +eKi DC++E+ l+ FUN_001437-T1 44 LDDFTENEETVFEKIpSDCFKEKELH 69 44669**********66*****9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (512 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1265 (0.0495205); expected 510.9 (0.02) Passed bias filter: 626 (0.0245058); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4924.22 // Query: FUN_001438-T1 [L=107] Description: FUN_001438 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00045 20.1 0.1 0.00051 20.0 0.1 1.0 1 Lectin_leg-like Legume-like lectin family Domain annotation for each model (and alignments): >> Lectin_leg-like Legume-like lectin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 2e-08 0.00051 11 74 .. 16 79 .. 13 103 .. 0.81 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 2e-08 Lectin_leg-like 11 kPylgqgskalp..eWeyggsaildsnqirltsdeqskkGslwtkspvaleswevevsFrvtgset 74 P l++ +++++ +W+ + i +n+++lt + +Gsl + s++ sw++ v F++ ++ FUN_001438-T1 16 SPALAKITREINqkHWKANHQYIYLENRVFLTWRKVRAEGSLVNDSNF--ASWQMAVRFVAPNEDV 79 577777777777779*******************999******99865..68*******9977743 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 581 (0.0227442); expected 510.9 (0.02) Passed bias filter: 382 (0.014954); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1067.50 // Query: FUN_001439-T1 [L=481] Description: FUN_001439 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-12 48.5 0.1 2.7e-12 47.8 0.1 1.4 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.8 0.1 1.1e-16 2.7e-12 44 210 .. 137 307 .. 93 312 .. 0.83 Alignments for each domain: == domain 1 score: 47.8 bits; conditional E-value: 1.1e-16 MACPF 44 kLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkl.eksklekskskgedvkiclsaeakasikngkvslkgckk 134 +L++++lk+ + Lp ++ ++ a y++f++++G Hvitsv+ G+ i++++ ++++ ++++ + + c+s+ +++ gk+++ +c + FUN_001439-T1 137 NLTKRLLKDFEILPLMFPEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAeSSESYSQRDFQIKS---CISLAGPTNV--GKLGVEACAN 227 4788888888888887777766667778***********************99888355556666666666...9999999999..9********9 PP MACPF 135 nssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAl 210 s+s+ ++ s+ +++ k +v+GGt ++ + +++e ++ +++ e ++++++++++ ++l++ ++ n+ +A+ FUN_001439-T1 228 VSNSEVTSAST--MNTVDKLIVRGGTRETRNalfnqRTKELIEKLMNEAGESNAAVEHSFRSIWDILQSRFkYGSDNYIRAV 307 99999988854..69999********97777999999999999999999999999999999999999887766777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (481 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 912 (0.0357017); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 4684.93 // Query: FUN_001440-T1 [L=229] Description: FUN_001440 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.9e-07 29.7 0.0 1.2e-06 29.3 0.0 1.4 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.0 4.8e-11 1.2e-06 37 100 .. 129 196 .. 81 218 .. 0.78 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 4.8e-11 MACPF 37 lknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilklekskl 100 l++ e +L++++lk+ + Lp + ++ a y++f++++G Hvitsv+ G+ i++++ e+s+ FUN_001440-T1 129 LDDVEISNLTKRLLKDFEILPLRFPEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAESSES 196 44444556888888888888887777766667777************************998765554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (229 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 633 (0.0247798); expected 510.9 (0.02) Passed bias filter: 468 (0.0183206); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2295.58 // Query: FUN_001441-T1 [L=295] Description: FUN_001441 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (295 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 874 (0.0342141); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2933.12 // Query: FUN_001442-T1 [L=528] Description: FUN_001442 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-13 52.2 6.6 1.6e-13 51.7 6.0 1.5 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain 0.16 12.4 0.1 0.37 11.2 0.1 1.6 1 Feld-I_B Allergen Fel d I-B chain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.7 6.0 1.9e-17 1.6e-13 2 210 .. 125 336 .. 122 342 .. 0.82 Alignments for each domain: == domain 1 score: 51.7 bits; conditional E-value: 1.9e-17 MACPF 2 sfsassef.kklsqklkskkksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyi 92 s s+s e+ +++ +++ + +++ k+k+ + + +l+n e kL++ fl++ +aLp++++k+ k+ y+kf+dk+G H+i s++ G+ i+++ FUN_001442-T1 125 SSSSSNEYsSNM--EVSGISLNILALKKKMFVKKECLTNVEISKLTKNFLDEYEALPKSINKPWKSHswqaYTKFLDKFGSHIILSIKSGSSIKQT 218 678888885555..888888888888888888888888888899**************9888877777888**********************997 PP MACPF 93 l.kleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenp 182 + ++++++ ++++ + + c+s+ +s+ gkv++++c++ s+ +k+ s+++++ k +vlGGt+ + + +++e +++ +++ e+ FUN_001442-T1 219 TfAQSSESYSERDFQIKS---CVSLAGPTSV--GKVGVDACGNISEIEKNRA--SNMNTQGKLIVLGGTKNTRNalhsqRTKELFEKLMNEADETD 307 527788999999999999...****999999..9*******97666555555..669************965558988888888888888888888 PP MACPF 183 dpIkfeltplsellkeep.kkkenlrqAl 210 +++ +++t++ + l++ + n+ +A+ FUN_001442-T1 308 AAVAHTFTSIWDVLRSRFkHGTDNYIRAV 336 88888888888888877655556666655 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 1.3e-05 0.11 34 74 .. 265 305 .. 253 311 .. 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.3e-05 GATase_3 34 deslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a + FUN_001442-T1 265 ASNMNTQGKLIVLGGTKNTRNALHSQRTKELFEKLMNEADE 305 455667899*************************9998765 PP >> Feld-I_B Allergen Fel d I-B chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 4.4e-05 0.37 25 49 .. 60 85 .. 47 92 .. 0.77 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 4.4e-05 Feld-I_B 25 lvnaTdeEkvAleKi.QDCynEeglk 49 l + T++E + +eKi DC++E+ l+ FUN_001442-T1 60 LDDFTENEETVFEKIpSDCFKEKELH 85 44669**********66*****9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (528 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1337 (0.052339); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 5262.72 // Query: FUN_001443-T1 [L=472] Description: FUN_001443 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-12 48.5 0.1 2.6e-12 47.8 0.1 1.4 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.8 0.1 1e-16 2.6e-12 44 210 .. 148 318 .. 104 323 .. 0.83 Alignments for each domain: == domain 1 score: 47.8 bits; conditional E-value: 1e-16 MACPF 44 kLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkl.eksklekskskgedvkiclsaeakasikngkvslkgckk 134 +L++++lk+ + Lp ++ ++ a y++f++++G Hvitsv+ G+ i++++ ++++ ++++ + + c+s+ +++ gk+++ +c + FUN_001443-T1 148 NLTKRLLKDFEILPLMFPEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAeSSESYSQRDFQIKS---CISLAGPTNV--GKLGVEACAN 238 4788888888888887777766667778***********************99888355556666666666...9999999999..9********9 PP MACPF 135 nssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAl 210 s+s+ ++ s+ +++ k +v+GGt ++ + +++e ++ +++ e ++++++++++ ++l++ ++ n+ +A+ FUN_001443-T1 239 VSNSEVTSAST--MNTVDKLIVRGGTRETRNalfnqRTKELIEKLMNEAGESNAAVEHSFRSIWDILQSRFkYGSDNYIRAV 318 99999988854..69999********97777999999999999999999999999999999999999887766777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (472 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 863 (0.0337835); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.38u 0.37s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4531.80 // Query: FUN_001444-T1 [L=528] Description: FUN_001444 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-13 52.2 6.6 1.6e-13 51.7 6.0 1.5 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 GATase_3 CobB/CobQ-like glutamine amidotransferase domain 0.16 12.4 0.1 0.37 11.2 0.1 1.6 1 Feld-I_B Allergen Fel d I-B chain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.7 6.0 1.9e-17 1.6e-13 2 210 .. 125 336 .. 122 342 .. 0.82 Alignments for each domain: == domain 1 score: 51.7 bits; conditional E-value: 1.9e-17 MACPF 2 sfsassef.kklsqklkskkksliiskakcslyqltlknseklkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyi 92 s s+s e+ +++ +++ + +++ k+k+ + + +l+n e kL++ fl++ +aLp++++k+ k+ y+kf+dk+G H+i s++ G+ i+++ FUN_001444-T1 125 SSSSSNEYsSNM--EVSGISLNILALKKKMFVKKECLTNVEISKLTKNFLDEYEALPKSINKPWKSHswqaYTKFLDKFGSHIILSIKSGSSIKQT 218 678888885555..888888888888888888888888888899**************9888877777888**********************997 PP MACPF 93 l.kleksklekskskgedvkiclsaeakasikngkvslkgckknssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenp 182 + ++++++ ++++ + + c+s+ +s+ gkv++++c++ s+ +k+ s+++++ k +vlGGt+ + + +++e +++ +++ e+ FUN_001444-T1 219 TfAQSSESYSERDFQIKS---CVSLAGPTSV--GKVGVDACGNISEIEKNRA--SNMNTQGKLIVLGGTKNTRNalhsqRTKELFEKLMNEADETD 307 527788999999999999...****999999..9*******97666555555..669************965558988888888888888888888 PP MACPF 183 dpIkfeltplsellkeep.kkkenlrqAl 210 +++ +++t++ + l++ + n+ +A+ FUN_001444-T1 308 AAVAHTFTSIWDVLRSRFkHGTDNYIRAV 336 88888888888888877655556666655 PP >> GATase_3 CobB/CobQ-like glutamine amidotransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 1.3e-05 0.11 34 74 .. 265 305 .. 253 311 .. 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.3e-05 GATase_3 34 deslgedadlvilpGgkntlqdlallresglkeaikeaaek 74 ++++++ +l++l+G+knt+++l ++r ++l e++ + a + FUN_001444-T1 265 ASNMNTQGKLIVLGGTKNTRNALHSQRTKELFEKLMNEADE 305 455667899*************************9998765 PP >> Feld-I_B Allergen Fel d I-B chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 4.4e-05 0.37 25 49 .. 60 85 .. 47 92 .. 0.77 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 4.4e-05 Feld-I_B 25 lvnaTdeEkvAleKi.QDCynEeglk 49 l + T++E + +eKi DC++E+ l+ FUN_001444-T1 60 LDDFTENEETVFEKIpSDCFKEKELH 85 44669**********66*****9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (528 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1337 (0.052339); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 5072.61 // Query: FUN_001445-T1 [L=483] Description: FUN_001445 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-12 46.9 0.1 8e-12 46.2 0.1 1.4 1 MACPF MAC/Perforin domain Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 0.1 3.1e-16 8e-12 44 210 .. 139 309 .. 95 314 .. 0.82 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 3.1e-16 MACPF 44 kLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkl.eksklekskskgedvkiclsaeakasikngkvslkgckk 134 +L++++lk+ + Lp ++ ++ a y++f++++G Hvitsv+ G+ i++++ ++++ ++++ + + c+s+ +++ gk+++ +c + FUN_001445-T1 139 NLTKRLLKDFEILPLMFPEPWLANawkpYHDFLETFGSHVITSVKRGSSIKQTTFAeSSESYSQRDFQIKS---CISLAGPTNV--GKLGVEACAN 229 4788888888888887777766667778***********************99888355556666666666...9999999999..9********9 PP MACPF 135 nssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAl 210 s+s+ ++ s+ +++ k +v+GGt ++ + +++e ++ +++ e ++++++++++ ++l++ ++ n+ +A+ FUN_001445-T1 230 VSNSEVTSAST--MNTIDKLIVRGGTRETRNalfnqRTKELIEKLMNEAGESNAAVEHSFRSIWDILQSRFkYGSDNYIRAV 309 99999988855..5777899******97777999999999999999999999999999999999999887766777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (483 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 914 (0.03578); expected 510.9 (0.02) Passed bias filter: 570 (0.0223136); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.43s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4660.38 // Query: FUN_001446-T1 [L=136] Description: FUN_001446 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (136 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 434 (0.0169896); expected 510.9 (0.02) Passed bias filter: 373 (0.0146017); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1371.30 // Query: FUN_001447-T1 [L=1069] Description: FUN_001447 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-57 192.7 1.1 9.6e-57 192.7 1.1 2.2 2 Reprolysin Reprolysin (M12B) family zinc metalloproteas 2.3e-28 99.4 8.0 2.3e-28 99.4 8.0 3.6 1 ADAM_CR ADAM cysteine-rich 2.1e-20 73.7 29.9 2.1e-20 73.7 29.9 4.5 2 Disintegrin Disintegrin 2.8e-19 70.6 0.8 2.8e-19 70.6 0.8 1.8 1 Reprolysin_5 Metallo-peptidase family M12 1.7e-13 51.4 0.2 3e-13 50.6 0.2 1.5 1 Reprolysin_2 Metallo-peptidase family M12B Reprolysin-lik 7.2e-11 43.2 0.4 1.3e-10 42.3 0.4 1.5 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-lik 4.8e-09 37.2 0.0 1.2e-08 35.9 0.0 1.7 1 Pep_M12B_propep Reprolysin family propeptide 1.3e-07 32.0 0.3 2.9e-07 30.8 0.3 1.6 1 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-lik ------ inclusion threshold ------ 0.023 15.6 0.5 0.023 15.6 0.5 6.8 5 ADAMTS_CR_2 ADAMTS cysteine-rich domain 2 0.11 12.0 0.0 0.45 9.9 0.0 2.0 2 Peptidase_M66 Peptidase M66 0.14 12.5 0.3 16 5.8 0.1 2.3 2 DUF2427 Domain of unknown function (DUF2427) 0.25 11.7 0.0 0.48 10.8 0.0 1.4 1 Peptidase_M10 Matrixin 0.27 11.7 0.1 0.64 10.5 0.1 1.6 1 Zincin_1 Zincin-like metallopeptidase Domain annotation for each model (and alignments): >> Reprolysin Reprolysin (M12B) family zinc metalloprotease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 192.7 1.1 4.9e-60 9.6e-57 1 200 [] 208 408 .. 208 408 .. 0.98 2 ? -4.0 0.0 8.9 1.7e+04 130 155 .. 704 730 .. 691 735 .. 0.68 Alignments for each domain: == domain 1 score: 192.7 bits; conditional E-value: 4.9e-60 Reprolysin 1 kYvelfivvdkqlfkklgsdtekvrqkvlevvnlvnsiykelnirvvLvglEiWtdedkievskdaeetLeeflkwreeklkkrkkhdaaqLlsgk 96 kYvel+iv+d++++ kl+ + ++v+++ ++++n+v+s+++++n+rv L +E+W+++d+iev++d ++ L++f+ +r+ l +++khd+a+L++ + FUN_001447-T1 208 KYVELIIVNDHSQYLKLR-SIAEVEKRSKSIANVVDSLFRAINVRVALIMVETWNQRDRIEVVEDSDRCLDNFMVYRNGELWRKQKHDNAMLITHR 302 8****************9.999************************************************************************** PP Reprolysin 97 efeaktvglayvgglCskeksgavnedkkknlealavilaheLghnlGlqhdeekkeCkCe...ekgvCimneeagsssgvkFskcsledfekflk 189 +f++ tvg a+++++C + ksg+v+ d+ kn a a+++ahe+ghn+G+ hde ++CkC+ ++++Cim+e a + ++++s+cs+e +ek+l+ FUN_001447-T1 303 SFKGATVGKAALMSMCGR-KSGGVVRDHDKNAAATAATVAHEMGHNFGMLHDEDIESCKCNspsDNQGCIMSEVAKGTPSTEWSSCSRESYEKYLN 397 *****************9.99***************************************9988899******99999999*************** PP Reprolysin 190 kqkgaCLlnkP 200 +++ +CL+n P FUN_001447-T1 398 RGMDSCLFNVP 408 *********99 PP == domain 2 score: -4.0 bits; conditional E-value: 8.9 Reprolysin 130 alavilaheLghnlGlqhdee.kkeCk 155 +++v + +g lG+ + ++ ++C+ FUN_001447-T1 704 VVVVCILLLVGVALGVIYRKRlMQKCR 730 344555667899999999888667675 PP >> ADAM_CR ADAM cysteine-rich # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 99.4 8.0 1.2e-31 2.3e-28 1 116 [] 503 619 .. 503 619 .. 0.93 Alignments for each domain: == domain 1 score: 99.4 bits; conditional E-value: 1.2e-31 ADAM_CR 1 dgtpCkeekayCykgkCksrdkqCkelfgkeaksapeaCyeevnskgdrfgnCgkkkkkkyvkCekedvlCGklqCenvke..lpelkeeatviqt 94 +g +C+++++yCy+g+C ++dkqCk+l+g+eaks+p+ Cy +vn++g+ gnC++ ++ y+kC++++ lCG+lqC+n+++ lp ++++++ + FUN_001447-T1 503 NGRSCANNNGYCYNGECPTHDKQCKDLWGHEAKSGPDVCY-KVNEQGTVRGNCHQPGNNVYIKCTQQNRLCGMLQCTNIDKieLPIIGSDKSSYAH 597 799*************************************.**************99999******************965116889999999999 PP ADAM_CR 95 kvkeekCvsldvhlekdvkdlg 116 ++ + C+s++++l++dv+d+g FUN_001447-T1 598 SFGDILCKSTSLSLGRDVPDPG 619 999999******9899999875 PP >> Disintegrin Disintegrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 1.4 4.9 9.6e+03 3 26 .. 356 377 .. 354 399 .. 0.55 2 ! 73.7 29.9 1.1e-23 2.1e-20 1 74 [. 423 497 .. 423 498 .. 0.95 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 4.9 Disintegrin 3 geeCDcGseeecekdkCcdaktCk 26 e+C c s ++ + C ++ k FUN_001447-T1 356 IESCKCNSPSDN--QGCIMSEVAK 377 577777755552..3454433333 PP == domain 2 score: 73.7 bits; conditional E-value: 1.1e-23 Disintegrin 1 eegeeCDcGseeece..kdkCcdaktCklkegaqCssgeCckekCqlksagtvCreakdeCdleeyCnGksaeCpe 74 eegeeCDcGs e+c+ +d Cc+a+tCkl+++++C++g+Cc+ kC+lk++g+vCre+ +eCdl+e+C+Gks+ Cp+ FUN_001447-T1 423 EEGEECDCGSIEDCKkySDGCCNATTCKLHPDSECDTGACCS-KCKLKPQGVVCREKLNECDLPEFCTGKSELCPS 497 89************545799**********************.8******************************97 PP >> Reprolysin_5 Metallo-peptidase family M12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.6 0.8 1.4e-22 2.8e-19 5 195 .] 210 385 .. 207 385 .. 0.86 Alignments for each domain: == domain 1 score: 70.6 bits; conditional E-value: 1.4e-22 Reprolysin_5 5 vallvaaDcsyvaafgg.daaqaniinmvntasnvyerefnislglanltisdstdpetaseasssgnssdlLnefq..sssawrgtqsddlavlt 97 v l+++ D+s + + + +++++ ++ n + + +r++n+++ l ++++++ d + ++s+ L++f + +++ +q++d+a+l+ FUN_001447-T1 210 VELIIVNDHSQYLKLRSiAEVEKRSKSIANVV-DSLFRAINVRVALIMVETWNQRDRIE-----VVEDSDRCLDNFMvyRNGELWRKQKHDNAMLI 299 8899******9999988756888888888888.8889********************87.....89**********999777777889999***** PP Reprolysin_5 98 lmtncstg.vglAwlgqlcnsgsagsvsesveksnsvvvstatewqvfaHEiGHnfGavHDcdsstassqcCplsastcdaggryiMnpsss.pni 191 +++++++ vg A l+++c +s+g v ++a ++ ++aHE+GHnfG HD d + +C+ + + ++ +iM++ ++ + + FUN_001447-T1 300 THRSFKGAtVGKAALMSMCGRKSGGVVRDH-------DKNAAATAATVAHEMGHNFGMLHDEDIE-----SCKCN--SPSDNQGCIMSEVAKgTPS 381 ******999***********9998888855.......467899********************64.....55443..3567788***999887777 PP Reprolysin_5 192 tafS 195 t++S FUN_001447-T1 382 TEWS 385 7776 PP >> Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.6 0.2 1.5e-16 3e-13 9 189 .. 204 392 .. 196 398 .. 0.62 Alignments for each domain: == domain 1 score: 50.6 bits; conditional E-value: 1.5e-16 Reprolysin_2 9 vevlnrvnqiYeeddieislglrneaeieattsasdsgnn......................rcnssttevrr.lnllsqleg....ekdydlahl 77 + +++v+ i +d + l+lr +ae+e + ++ ++ r ++ ++ r n++ +g ++++d+a+l FUN_001447-T1 204 KNEIKYVELIIV-NDHSQYLKLRSIAEVEKRSKSIANVVDslfrainvrvalimvetwnqrdRIEVVEDSDRClDNFMVYRNGelwrKQKHDNAML 298 555555555555.566666666666666666555555544556666666666666666555422333332222222222222311114699***** PP Reprolysin_2 78 vllgefsggvlGLAyvgqicqkkassrktntglsttanygsaveesqeidvvaHEvGHnFGatHdndgsssasegceenaatsaesangkfiMa.p 172 ++++ f+g+++G A + ++c +k++ g++ + + vaHE+GHnFG Hd+d++ s++ + n+++ +n iM+ FUN_001447-T1 299 ITHRSFKGATVGKAALMSMCGRKSG------GVV---RDHDKNA-AATAATVAHEMGHNFGMLHDEDIE-SCK-C---NSPS----DNQGCIMSeV 375 ********************66554......566...2223332.4567789***************99.333.3...4555....4455789935 PP Reprolysin_2 173 asksnntqFSpcsisli 189 a t++S cs+++ FUN_001447-T1 376 AKGTPSTEWSSCSRESY 392 5669999******9875 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.3 0.4 6.7e-14 1.3e-10 5 123 .] 235 353 .. 231 353 .. 0.91 Alignments for each domain: == domain 1 score: 42.3 bits; conditional E-value: 6.7e-14 Reprolysin_3 5 aslveaanqvyerelgirlqlaaiiitssadtpyttkdaleildeaaeviste.rgqsgydlvhlftkrdv.sgvgGlAyvgavcnsskkfglnsg 98 +s+ + +++ ++ +++r+ l+ +++++++d ++ +d+++ ld+++ + e ++++ d + l+t+r + + + G A + ++c +++ g++++ FUN_001447-T1 235 KSIANVVDSLFR-AINVRVALIMVETWNQRDRIEVVEDSDRCLDNFMVYRNGElWRKQKHDNAMLITHRSFkGATVGKAALMSMCGRKSG-GVVRD 328 6788999****9.9*******************************998888877789999***********9999**********98888.88888 PP Reprolysin_3 99 ssplgdtgadtfaHEiGHnfGanHt 123 + + + +a t+aHE+GHnfG H+ FUN_001447-T1 329 HDKNAAATAATVAHEMGHNFGMLHD 353 88888899**************997 PP >> Pep_M12B_propep Reprolysin family propeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 0.0 6.3e-12 1.2e-08 21 93 .] 48 123 .. 33 123 .. 0.84 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 6.3e-12 Pep_M12B_propep 21 skrrrrslseeees...eeqlsYrlsaegkelhLnLeknrellapgftvetygkdgeevtespqeeehChYqGhve 93 + +rr++s++++ ++ + ++ +gk+++L +nr ll+ +++ ++++dg+ev + ++++++C+YqG+v+ FUN_001447-T1 48 QGLWRREISTRSSLgdhIDKAVFFFRGFGKNFVLVVAQNRVLLPANYVSRSFSADGAEVISGHEKTDNCFYQGTVQ 123 445666666555446666888899**************************************************97 PP >> Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.8 0.3 1.5e-10 2.9e-07 18 184 .. 223 377 .. 207 395 .. 0.71 Alignments for each domain: == domain 1 score: 30.8 bits; conditional E-value: 1.5e-10 Reprolysin_4 18 elgsvdevraainalVavinevyerdlnvrLaLvistrdviytdsetddfa.lddlaedlnneslaaltstrgelnaDlaallrqdrasqqevgva 112 +l s++ev+++ + +v++ + r +nvr aL+ + t + d ++ ++d+ l+n + + ++++D+a l+ ++ vg a FUN_001447-T1 223 KLRSIAEVEKRSKSIANVVDSLF-RAINVRVALI-----MVETWNQRDRIEvVEDSDRCLDNFMVYRNGELWRKQKHDNAMLITHRSFKGATVGKA 312 45788999999999888888888.7899999999.....33344444444215667777777777777666678999*****99998999999999 PP Reprolysin_4 113 wvgavclsarqvnkkgsgfaassderd.eyditfAHEiGHqfGaaHdkeseseglsvaveegsgstImayast 184 + +c k+ g+ + d++ t+AHE+GH+fG+ Hd + es+ ++ + + Im+ +++ FUN_001447-T1 313 ALMSMC------GRKSGGVVRDHDKNAaATAATVAHEMGHNFGMLHDEDIESCKCNSPSD--NQGCIMSEVAK 377 999999......334555555555555144669******************999988765..34568877765 PP >> ADAMTS_CR_2 ADAMTS cysteine-rich domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.9 0.13 2.5e+02 26 65 .. 352 389 .. 338 391 .. 0.80 2 ? -1.0 8.5 1.8 3.5e+03 34 68 .. 487 519 .. 464 520 .. 0.72 3 ? 2.6 0.2 0.14 2.7e+02 8 45 .. 523 542 .. 520 559 .. 0.56 4 ? 1.5 2.0 0.31 6e+02 11 39 .. 554 581 .. 546 585 .. 0.80 5 ? 15.6 0.5 1.2e-05 0.023 50 69 .] 620 639 .. 600 639 .. 0.86 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.13 ADAMTS_CR_2 26 eesvCkklwCskpekekecktkeapaadgTsCgekkwClk 65 ++++ ++ C+ p++++ c ++++a gT+ e C + FUN_001447-T1 352 HDEDIESCKCNSPSDNQGCI--MSEVAKGTPSTEWSSCSR 389 467889999*****999999..778999999999999976 PP == domain 2 score: -1.0 bits; conditional E-value: 1.8 ADAMTS_CR_2 34 wCskpekekecktkeapaadgTsCgekk.wClkgkC 68 +C+ ++ + c +++ + +g sC++++ +C++g+C FUN_001447-T1 487 FCTGKS--ELCP-SNKYVHNGRSCANNNgYCYNGEC 519 688866..4665.777899*****98776******* PP == domain 3 score: 2.6 bits; conditional E-value: 0.14 ADAMTS_CR_2 8 deQCrlifgpeskkcpkkeesvCkklwCskpekekeck 45 d+QC+ +g e+k+ p+ c+ FUN_001447-T1 523 DKQCKDLWGHEAKSGPD------------------VCY 542 66777777766665544..................333 PP == domain 4 score: 1.5 bits; conditional E-value: 0.31 ADAMTS_CR_2 11 CrlifgpeskkcpkkeesvCkklwCskpe 39 C + ++ + kc+++ ++ C +l C++ + FUN_001447-T1 554 CHQPGNNVYIKCTQQ-NRLCGMLQCTNID 581 555555668899998.*********9855 PP == domain 5 score: 15.6 bits; conditional E-value: 1.2e-05 ADAMTS_CR_2 50 paadgTsCgekkwClkgkCv 69 ++gT+Cge+k Cl++kC+ FUN_001447-T1 620 MTVEGTKCGENKLCLDRKCM 639 568****************6 PP >> Peptidase_M66 Peptidase M66 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.2 2.3e+03 234 267 .. 143 177 .. 141 189 .. 0.81 2 ? 9.9 0.0 0.00023 0.45 161 209 .. 298 353 .. 228 367 .. 0.66 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.2 Peptidase_M66 234 yDanhneflsnllaktseyknckkeselda.dgrc 267 yD n +f+++l +t++++ +++++++ ++rc FUN_001447-T1 143 YDGNETYFIQPLPGNTEQQHILFRSKDMVQgEKRC 177 9**************99977776666666647776 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00023 Peptidase_M66 161 lltalkanGkyang..yGGlgggssGivtgda.....tltgifiHEqGHalGLpHy 209 l+t+ +G + + g sG v+ d+ + + HE+GH++G+ H FUN_001447-T1 298 LITHRSFKGATVGKaaLMSMCGRKSGGVVRDHdknaaATAATVAHEMGHNFGMLHD 353 55555555554444442233333344455554111114567899***********4 PP >> DUF2427 Domain of unknown function (DUF2427) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.026 51 38 93 .. 80 135 .. 69 144 .. 0.88 2 ? 5.8 0.1 0.0081 16 43 72 .. 696 725 .. 689 730 .. 0.85 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.026 DUF2427 38 vLglaksrwylpvqivslvlavlglllghiykgstPd.lypnniyaklawillilla 93 vL +a+ r+ lp+ vs + + g+ + + ++++ + +y++++ + ++ i+++ FUN_001447-T1 80 VLVVAQNRVLLPANYVSRSFSADGAEVISGHEKTD-NcFYQGTVQGLQHSVVAISTC 135 8999*****************************99.55******9988888888875 PP == domain 2 score: 5.8 bits; conditional E-value: 0.0081 DUF2427 43 ksrwylpvqivslvlavlglllghiykgst 72 +s+ ++++ +v ++l+++g++lg+iy+++ FUN_001447-T1 696 ESSGTVAAVVVVCILLLVGVALGVIYRKRL 725 4888999********************986 PP >> Peptidase_M10 Matrixin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00024 0.48 102 130 .. 309 358 .. 248 366 .. 0.73 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00024 x.....................xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_M10 102 k.....................eegvdlflvavHeiGHaLGLeHssdeea 130 ++++ + ++He+GH G+ H +d e+ FUN_001447-T1 309 VgkaalmsmcgrksggvvrdhdKNAAATAATVAHEMGHNFGMLHDEDIES 358 055555555555555555555577788888999***********988765 PP >> Zincin_1 Zincin-like metallopeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.1 0.00032 0.64 63 94 .. 326 358 .. 322 362 .. 0.83 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00032 Zincin_1 63 aeteeeleeevrhtlvhEighhfG.lsdedlee 94 ++++++ ++ + t+ hE+gh fG l ded+e+ FUN_001447-T1 326 VRDHDKNAAATAATVAHEMGHNFGmLHDEDIES 358 5667777888999***********778999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1069 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1416 (0.0554316); expected 510.9 (0.02) Passed bias filter: 713 (0.0279115); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.47u 0.38s 00:00:00.85 Elapsed: 00:00:00.41 # Mc/sec: 10438.90 // Query: FUN_001448-T1 [L=172] Description: FUN_001448 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-38 133.0 13.4 1.3e-38 132.8 13.4 1.1 1 TMEM128 TMEM128 protein Domain annotation for each model (and alignments): >> TMEM128 TMEM128 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.8 13.4 4.9e-43 1.3e-38 4 124 .] 52 170 .. 49 170 .. 0.96 Alignments for each domain: == domain 1 score: 132.8 bits; conditional E-value: 4.9e-43 TMEM128 4 ldkleallwilaallilyytdfvevllederinrlwlylgllllgvnlliflylavylpyikkvsyenwektapraipiatvlgvvsfilfiialW 99 + + ++++w+laal+++yy df+ l d ri+r+wly+g l+gvnl+i++y++++l+y+ ++ ++w+k++p++ipiat+++++++i+ ++alW FUN_001448-T1 52 RINSHSVFWMLAALAVFYYSDFYIALRVDSRIHRTWLYVGGGLIGVNLSIGCYCVLWLSYY--KKITDWDKHSPYIIPIATASFIAGMICSTYALW 145 66789********************************************************..7889***************************** PP TMEM128 100 pvwgflTplilfvlfmgvivvlsll 124 p+w +lTp+i+f+lfmgvi++++l+ FUN_001448-T1 146 PIWRILTPFIVFTLFMGVIFLATLI 170 ********************99876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (172 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 823 (0.0322177); expected 510.9 (0.02) Passed bias filter: 437 (0.0171071); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1720.75 // Query: FUN_001448-T2 [L=139] Description: FUN_001448 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-23 83.3 3.0 3.2e-23 83.0 3.0 1.1 1 TMEM128 TMEM128 protein Domain annotation for each model (and alignments): >> TMEM128 TMEM128 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.0 3.0 1.3e-27 3.2e-23 4 92 .. 52 138 .. 49 139 .] 0.95 Alignments for each domain: == domain 1 score: 83.0 bits; conditional E-value: 1.3e-27 TMEM128 4 ldkleallwilaallilyytdfvevllederinrlwlylgllllgvnlliflylavylpyikkvsyenwektapraipiatvlgvvsfi 92 + + ++++w+laal+++yy df+ l d ri+r+wly+g l+gvnl+i++y++++l+y+ ++ ++w+k++p++ipiat+++++++i FUN_001448-T2 52 RINSHSVFWMLAALAVFYYSDFYIALRVDSRIHRTWLYVGGGLIGVNLSIGCYCVLWLSYY--KKITDWDKHSPYIIPIATASFIAGMI 138 66789********************************************************..7889*******************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 632 (0.0247407); expected 510.9 (0.02) Passed bias filter: 448 (0.0175377); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1410.36 // Query: FUN_001449-T1 [L=515] Description: FUN_001449 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-13 50.3 0.6 9.2e-13 49.3 0.6 1.5 1 MACPF MAC/Perforin domain ------ inclusion threshold ------ 0.085 12.3 4.7 6.3 6.2 0.0 2.2 2 DUF913 Domain of Unknown Function (DUF913) 0.097 11.4 20.1 0.15 10.8 20.1 1.2 1 Nop14 Nop14-like family 0.12 12.3 17.8 0.22 11.5 17.8 1.3 1 PPP4R2 PPP4R2 0.13 11.0 14.6 0.19 10.4 14.6 1.1 1 CDC45 CDC45 0.32 11.2 11.3 0.57 10.4 11.3 1.3 1 Pox_Ag35 Pox virus Ag35 surface protein 0.39 11.6 8.3 0.8 10.6 8.3 1.5 1 RPA43_OB RPA43 OB domain in RNA Pol I 0.47 11.7 4.1 1.3 10.3 4.1 1.7 1 MRNIP MRN-interacting protein 1.9 9.2 10.6 4.7 8.0 10.6 1.6 1 Vfa1 AAA-ATPase Vps4-associated protein 1 3 8.0 12.7 5.4 7.1 12.7 1.3 1 mS26 Small ribosomal subunit protein mS26 3.6 8.5 13.1 6.7 7.6 12.1 1.9 2 Vma22_CCDC115 Vma22/CCDC115 4.4 8.2 40.0 10 7.0 40.0 1.5 1 Prothymosin Prothymosin/parathymosin family 4.8 6.2 9.1 7 5.7 9.1 1.1 1 DUF740 Protein of unknown function (DUF740) 6.2 5.9 5.9 9.1 5.4 5.9 1.1 1 Presenilin Presenilin 6.9 6.7 15.7 50 3.8 0.0 2.3 2 Nop52 Nucleolar protein,Nop52 9.1 6.2 23.7 14 5.5 23.7 1.2 1 CobT Cobalamin biosynthesis protein CobT 9.3 7.0 9.4 16 6.2 9.4 1.3 1 RNA_pol_Rpc4 RNA polymerase III RPC4 Domain annotation for each model (and alignments): >> MACPF MAC/Perforin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.3 0.6 6.1e-16 9.2e-13 42 211 .. 145 318 .. 100 323 .. 0.82 Alignments for each domain: == domain 1 score: 49.3 bits; conditional E-value: 6.1e-16 MACPF 42 klkLseeflkalsaLpsnydkaakat....yikfidkYGTHvitsvslGGkivyilkleksklekskskgedvkiclsaeakasikngkvslkgck 133 lkL + fl++l+aLp ++ k+ + y+kf+d++GTHvi s++lG+ i++ + e+s+ + ++ ic++ + i g ++ k+c+ FUN_001449-T1 145 VLKLEKNFLEDLEALPLTIRKPWASNswrvYRKFLDTFGTHVIESAKLGSSIKQMTLAESSESYSERDFFVK--ICTKFTGLTHI--GDIGTKACQ 236 478**************9988876667888***********************9998888776655555555..67777776778..99******* PP MACPF 134 knssstkekksssqeeesskievlGGtpdsed.....dkeetyseWlesvkenpdpIkfeltplsellkeep.kkkenlrqAle 211 +ss+ +k ++ e++ +v+GGt+ + + e+ ++ ++ e +++ ++++ + ++l++ ++en+ +Al+ FUN_001449-T1 237 RINSSEINKVGKI--ETQDTLIVRGGTKKLRNalfeeRSGEAIEKFMNAANESDTAVGYNFRAIWDILQSRFkYGSENYIRALN 318 **********998..99999*******977668999988889999999999999999999999999998877678888888884 PP >> DUF913 Domain of Unknown Function (DUF913) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.0042 6.3 118 150 .. 32 64 .. 25 138 .. 0.90 2 ? 5.1 3.6 0.009 14 295 333 .. 459 494 .. 424 503 .. 0.41 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0042 DUF913 118 GssvwslavnilsdfihnePTsfaviqeaglsk 150 G v+ +n+l+df+ ne T f+ + +++ FUN_001449-T1 32 GKAVYPRKINLLADFVENEKTIFERLPSECIVE 64 999********************9987766665 PP == domain 2 score: 5.1 bits; conditional E-value: 0.009 DUF913 295 sseeetkgeekssededvemedaeeaesdseeeeekese 333 ++ee+++ ee+++e+e+ e e++ +e+++eeeee+e+e FUN_001449-T1 459 DEEEDEDDEEEEEEEEE-EEEEE--EEEEEEEEEEEEEE 494 22222222221111111.11111..11112222222222 PP >> Nop14 Nop14-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 20.1 9.8e-05 0.15 362 402 .. 454 496 .. 422 512 .. 0.46 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 9.8e-05 Nop14 362 elee..eeeeedeeeeeeeeeeeeeeededdlsdleseeeeed 402 ++ eee+ed+eeeeeeeeeeeeee+e++++++e+eeeee+ FUN_001449-T1 454 LSDLydEEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 496 2222111222222222222222211111111111111212222 PP >> PPP4R2 PPP4R2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 17.8 0.00014 0.22 244 281 .. 459 495 .. 405 497 .. 0.56 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00014 PPP4R2 244 eekdedeeedeedsdyeeeevkrekedeeeeeeeeeee 281 ++ede+++ee+++ eeee+++e+e+eeeeeeeeeee FUN_001449-T1 459 D-EEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 495 1.223333333333333333333333333333333333 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 14.6 0.00013 0.19 123 163 .. 455 494 .. 424 508 .. 0.43 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00013 CDC45 123 ealeeeeeedeedeeeeeeddeeeeeeeeeeedeeeeeede 163 +l +eee++ +deeeeee++eeeeeeeeeee+eeeeee+e FUN_001449-T1 455 SDLYDEEEDE-DDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 494 2222222221.221111111111111111111111111111 PP >> Pox_Ag35 Pox virus Ag35 surface protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 11.3 0.00038 0.57 79 117 .. 458 495 .. 420 510 .. 0.53 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00038 Pox_Ag35 79 kaeeeevedseedeenendeeesekspqaeeekseesae 117 eee ed+ee+ee+e++eee e+++++eee+ ee++e FUN_001449-T1 458 YDEEE-DEDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 495 22222.222222222222222222222222222222212 PP >> RPA43_OB RPA43 OB domain in RNA Pol I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 8.3 0.00053 0.8 38 75 .. 411 490 .. 402 500 .. 0.64 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00053 RPA43_OB 38 kdwkwee...............................................eeekeeeekeeeeeeeekeedeeedeeeeee 75 ++w+w++ + +e+eeeeeeee+ee+eee+eeeeee FUN_001449-T1 411 RNWRWHGcdwkvkgsvcrcfnggidqrvevwtspgrdivkkdklsdlydeeedeD-----DEEEEEEEEEEEEEEEEEEEEEEEE 490 5899999999999999999999999999999999999999999999998654331.....2222222222222222222222222 PP >> MRNIP MRN-interacting protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 4.1 0.00086 1.3 49 92 .. 450 493 .. 421 506 .. 0.53 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00086 MRNIP 49 qklnlekgekeeeeaeelkekkeeeeekeeeeeeekleeeeese 92 +k l+ +eee ++ ++e++eeeee+eeeeeee++eeeee+e FUN_001449-T1 450 KKDKLSDLYDEEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEEE 493 44444444444433322222222222222222222222222222 PP >> Vfa1 AAA-ATPase Vps4-associated protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 10.6 0.0031 4.7 96 144 .. 456 504 .. 435 510 .. 0.48 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0031 Vfa1 96 e..kkekdkkkekekkkkkekekkeekkkelekeeeklaeeekkvkkykLh 144 + + +++++++e+++++e+e++ee+++e+e+eee+++eee+ + + L+ FUN_001449-T1 456 DlyD--EEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDLAAFGLQ 504 2222..222222222222222223444444444444444555555566665 PP >> mS26 Small ribosomal subunit protein mS26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 12.7 0.0036 5.4 101 154 .. 446 499 .. 436 506 .. 0.84 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0036 mS26 101 kaelRReYLkeayrkeekrlekkeelkekkeeeeeeekeeeeekleeskssdlt 154 ++ ++++ L++ y +ee++ ++ee +e++eeeeeee+eeeee+ ee++++dl FUN_001449-T1 446 RDIVKKDKLSDLYDEEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDLA 499 56678889**********999999999999999998888888888888888875 PP >> Vma22_CCDC115 Vma22/CCDC115 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 3.6 5.4e+03 5 43 .. 6 42 .. 4 81 .. 0.53 2 ? 7.6 12.1 0.0044 6.7 77 124 .. 459 502 .. 436 504 .. 0.42 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 3.6 Vma22_CCDC115 5 lelLelldqyeelleqlqknfseGflnLsRAnysnkrsl 43 + l++ll+ ++ell++ + ++++ +L++A y k +l FUN_001449-T1 6 ILLISLLAPFRELLAKSNPHLIK--EELGKAVYPRKINL 42 56777777777777777777654..35555555555444 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0044 Vma22_CCDC115 77 kkkeedkeekkeeedsklknrkkkekeekkkteekkkkkskDPirwFG 124 +++e++++e e++++++++++e+ee++++ee++++++++ + FG FUN_001449-T1 459 DEEEDEDDE----EEEEEEEEEEEEEEEEEEEEEEEEEEEEEDLAAFG 502 222211111....11112222222222223333333444455566665 PP >> Prothymosin Prothymosin/parathymosin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 40.0 0.0066 10 47 85 .. 460 496 .. 445 506 .. 0.43 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0066 Prothymosin 47 eeeeevekeeeeeeeeeeeeeeeeeeeeeedgeeeeeea 85 eee+e +eeeeeeeeeeeeeeeeeeeee++eeeeee+ FUN_001449-T1 460 EEEDED--DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 496 222222..2222222222222222222222222222222 PP >> DUF740 Protein of unknown function (DUF740) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 9.1 0.0047 7 109 195 .. 416 495 .. 392 508 .. 0.50 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0047 DUF740 109 ksCDvRvrntLwsLFsqDdeervetkvekltassneaeeeiskssvkepvleekeee.eeeeeeeeleeelndnvieeivEeeeesee 195 + CD +v+ ++ F+ ++rve t+ + +k +++ + +e+e+e +eeeeeee+eee ++++ ee Eeeee+ee FUN_001449-T1 416 HGCDWKVKGSVCRCFNGGIDQRVEVW----TSPGRDIV---KKDKLSD-LYDEEEDEdDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 495 67888888888888887665555433....22222222...2222222.222222220222222222221222222222222222222 PP >> Presenilin Presenilin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 5.9 0.0061 9.1 295 332 .. 462 494 .. 430 506 .. 0.41 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.0061 Presenilin 295 esseaessteesseekekeeseeeseeekeeeeeeeee 332 e +++e+++ee++ee e+eee+ee +eeeeeeeee FUN_001449-T1 462 EDEDDEEEEEEEEEE----EEEEEEEE-EEEEEEEEEE 494 111111111111111....11111111.1111111111 PP >> Nop52 Nucleolar protein,Nop52 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.034 50 184 212 .. 9 46 .. 3 87 .. 0.68 2 ? 2.7 13.3 0.076 1.1e+02 208 252 .. 455 493 .. 436 501 .. 0.40 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.034 Nop52 184 ekllepfikllakskdkvlrkkikeelf.........e 212 +ll+pf +llaks+ + +++++ ++++ FUN_001449-T1 9 ISLLAPFRELLAKSNPHLIKEELGKAVYprkinlladF 46 579************************95544433331 PP == domain 2 score: 2.7 bits; conditional E-value: 0.076 Nop52 208 eelfederlkewrkeekeeeeeeeeeeeeeeeeekeeeeetkqkn 252 ++l+ de+ e ++ee+eeeeeeeeeeeeeeeee+eeee + FUN_001449-T1 455 SDLY-DEEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEE-----E 493 3344.3333222222222222222222222221111111.....1 PP >> CobT Cobalamin biosynthesis protein CobT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 23.7 0.0095 14 204 245 .. 455 496 .. 445 511 .. 0.40 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0095 CobT 204 aeelgeepeeedeeeeeeeeeeeeeeeeeeeeeedddqeeee 245 ++ +ee++e+deeeeeeeeeeeeeeeeeeeeee++++eeee FUN_001449-T1 455 SDLYDEEEDEDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 496 422222222222222222222222222222222222222222 PP >> RNA_pol_Rpc4 RNA polymerase III RPC4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 9.4 0.011 16 29 70 .. 463 495 .. 442 510 .. 0.38 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.011 RNA_pol_Rpc4 29 eeeeekeeeekekeekeekeekkkkkkeekkkkkskekastl 70 +e++e+eee +ee++++++ee+++++++e+++++ FUN_001449-T1 463 DEDDEEEEE---------EEEEEEEEEEEEEEEEEEEEEEEE 495 111111111.........111111111111111111111111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (515 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2515 (0.0984537); expected 510.9 (0.02) Passed bias filter: 1344 (0.052613); expected 510.9 (0.02) Passed Vit filter: 386 (0.0151106); expected 25.5 (0.001) Passed Fwd filter: 75 (0.002936); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.51u 0.44s 00:00:00.95 Elapsed: 00:00:00.42 # Mc/sec: 4889.57 // Query: FUN_001450-T1 [L=166] Description: FUN_001450 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-22 80.1 2.4 1.7e-22 79.5 2.4 1.3 1 Homeodomain Homeodomain 0.0083 16.5 0.4 0.018 15.3 0.4 1.5 1 Homeobox_KN Homeobox KN domain ------ inclusion threshold ------ 0.17 12.3 1.1 8.9 6.8 0.0 2.3 2 CATASP CATRA-Associated Small Protein Domain annotation for each model (and alignments): >> Homeodomain Homeodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.5 2.4 1.9e-26 1.7e-22 1 57 [] 99 155 .. 99 155 .. 0.99 Alignments for each domain: == domain 1 score: 79.5 bits; conditional E-value: 1.9e-26 Homeodomain 1 rrkRttftkeqleeLekeFeenrypsaeereeLAkklgLserqVkvWFqNrRakekk 57 +r+Rt+ft+ qle+Le+eF + y+ +r +LA++l+LserqVkvWFqNrR+k+k+ FUN_001450-T1 99 KRSRTSFTPAQLERLEEEFSLDMYVVGLKRMKLANELSLSERQVKVWFQNRRMKYKR 155 89*****************************************************98 PP >> Homeobox_KN Homeobox KN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.4 2.2e-06 0.018 16 39 .. 128 151 .. 127 152 .. 0.91 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.2e-06 Homeobox_KN 16 KeeLaketglsrkqisnWFiNaRr 39 + +La+e ls++q++ WF N R+ FUN_001450-T1 128 RMKLANELSLSERQVKVWFQNRRM 151 5689******************96 PP >> CATASP CATRA-Associated Small Protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.0011 8.9 28 72 .. 32 76 .. 29 79 .. 0.90 2 ? 3.6 1.3 0.01 87 54 76 .. 82 104 .. 76 114 .. 0.83 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0011 CATASP 28 aleaAlragdvdalreavadLelagpvRatrlgdesetpiPervr 72 ++ + r++++ +l++ v ++ ++ Ra+ +++++ ++i e+v FUN_001450-T1 32 SMDGTTRRDSLVGLQRFVYSSQIFSHSRASHADSRPVVSIGENVV 76 67888999*****************************99998875 PP == domain 2 score: 3.6 bits; conditional E-value: 0.01 CATASP 54 vRatrlgdesetpiPervrervn 76 +Ra+ ++++++ p P++ r r+ FUN_001450-T1 82 PRAAHAQPRPSLPSPKPKRSRTS 104 7******************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (166 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 781 (0.0305735); expected 510.9 (0.02) Passed bias filter: 532 (0.020826); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1628.28 // Query: FUN_001451-T1 [L=148] Description: FUN_001451 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0027 18.8 0.0 0.0035 18.5 0.0 1.2 1 Fuz_longin_3 Third Longin domain of FUZ, MON1 and HPS1 Domain annotation for each model (and alignments): >> Fuz_longin_3 Third Longin domain of FUZ, MON1 and HPS1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 1.4e-07 0.0035 31 98 .. 19 131 .. 3 135 .. 0.86 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 1.4e-07 Fuz_longin_3 31 rrrLrafYkslhstlhskerklkllykvse.sekllawite..............................................tfeLyvlfs 79 +++++ + +++h ++ +++ + ++++ ++ +w+++ ++eL +++ FUN_001451-T1 19 KQKIWDMWTYIHTYVLL--GHTFIAVRDGDfLFTYCLWFEDtsgnpvspqsplpvlygapppgilsssffkdlknwcfpsapanaicCYELMCVHV 112 56777777777777777..66666666667677899999999999999999999999999999999999999************************ PP Fuz_longin_3 80 plvpkaalissankllkwi 98 +lvp + + +++++l++++ FUN_001451-T1 113 GLVPVQFAAKHIRSLAAAL 131 ****************987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (148 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 427 (0.0167156); expected 510.9 (0.02) Passed bias filter: 335 (0.0131141); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1453.26 // Query: FUN_001452-T1 [L=608] Description: FUN_001452 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-15 56.2 0.0 1.4e-14 54.8 0.0 1.8 1 Fuz_longin_1 First Longin domain of FUZ, MON1 and HPS1 3.3e-08 34.1 3.1 4.5e-08 33.7 0.3 2.6 3 Fuz_longin_2 Second Longin domain of FUZ, MON1 and HPS1 ------ inclusion threshold ------ 0.014 15.7 0.2 0.034 14.4 0.2 1.7 1 HEPN_DZIP3 DZIP3/ hRUL138-like HEPN 0.074 13.6 0.1 0.17 12.4 0.1 1.6 1 UCMA Unique cartilage matrix associated protein Domain annotation for each model (and alignments): >> Fuz_longin_1 First Longin domain of FUZ, MON1 and HPS1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.8 0.0 2.3e-18 1.4e-14 1 122 [. 2 150 .. 2 153 .. 0.91 Alignments for each domain: == domain 1 score: 54.8 bits; conditional E-value: 2.3e-18 Fuz_longin_1 1 khllvlssaGkpiytrygde........................sesllfslfgvlqavisfmqdqkdeltsisae.ntkvVflekeplllvavsr 71 k+ll+ +s+ +++++ ++ + s+l++l++++++++++m+d ++ +si +e +t +Vf++++ l++ av+ FUN_001452-T1 2 KCLLIINSLPDILFIHADKGfikhvnklssdagfidkdhneeemDMSALSQLLSPMITSLTYMNDLGNPFSSILCEdGTLFVFRQFNDLVFTAVNG 97 89**************9999********************************************************9******************* PP Fuz_longin_1 72 s.gesesqLrrqLevvytqilsvlglaqltklfer..renedlrkllsgledll 122 + +ese+ L+r+L+v + + +++g a l+ l+ + +++ +k l +l+d++ FUN_001452-T1 98 DgEESEDFLKRKLSVSHKLATMHYG-ASLELLKPEilSAQKKAWKTLGSLIDTW 150 *9***********************.7777666521144677777777777776 PP >> Fuz_longin_2 Second Longin domain of FUZ, MON1 and HPS1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 1.9 1.2e+04 31 69 .. 52 88 .. 51 100 .. 0.72 2 ! 33.7 0.3 7.1e-12 4.5e-08 2 67 .. 196 260 .. 195 286 .. 0.89 3 ? -1.0 0.1 0.45 2.9e+03 60 83 .. 407 430 .. 396 441 .. 0.69 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 1.9 Fuz_longin_2 31 lllfllvessssfksaeswipiclpkfnpgvlhalvsfl 69 +ll+ +++s++ ++ ++ p + + +g+l+++ +f FUN_001452-T1 52 QLLSPMITSLTYMN--DLGNPFSSILCEDGTLFVFRQFN 88 68888999999988..66666666667777777766665 PP == domain 2 score: 33.7 bits; conditional E-value: 7.1e-12 Fuz_longin_2 2 sllfalllvsnklvalvrskka.sLhpsDllllfllvessssfksaeswipiclpkfnpgvlhalvs 67 ++++a+llv+ kl+al++s++a +L+++D+l++++l+ ++ +++ ++ ip++l p ++h +++ FUN_001452-T1 196 NVVHAMLLVNTKLLALYSSRNAsELKAVDILMITVLLHNIFPHS--KQPIPLSLNRTPPPMAHSVIH 260 689***************************************99..899999998888888887765 PP == domain 3 score: -1.0 bits; conditional E-value: 0.45 Fuz_longin_2 60 gvlhalvsfllgqnlvllllsgdk 83 +h+l + lg+++vl+l+s k FUN_001452-T1 407 YLPHVLHFVNLGTGTVLVLVSETK 430 567777777778888888888766 PP >> HEPN_DZIP3 DZIP3/ hRUL138-like HEPN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.2 5.3e-06 0.034 4 74 .. 182 255 .. 179 261 .. 0.78 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 5.3e-06 HEPN_DZIP3 4 Lqkvlaknkvk.lqsl.kkkvlnksqwekLyPasssvvsskdfDitLlvvLlrnic.gltppat.gwdklPaatD 74 L+++l+ ++k q++ + +l +++ Ly++++ + ++k Di +++vLl ni+ + ++p + ++ P+ FUN_001452-T1 182 LNTTLTMARSKgDQNVvHAMLLVNTKLLALYSSRNAS-ELKAVDILMITVLLHNIFpHSKQPIPlSLNRTPPPMA 255 66777777777544443577899999999****9998.******************8888885558888876655 PP >> UCMA Unique cartilage matrix associated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 2.7e-05 0.17 40 91 .. 346 395 .. 334 398 .. 0.75 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.7e-05 UCMA 40 kedakrkifmqesdasnflkrrgkrspksqdeinaenrqrlaaderrreyye 91 + +k+ f + + + ++l r+ +rs ++de + e+ + errreyy FUN_001452-T1 346 TSVLKENFFTPTATTPEIL-RKMRRSEETKDETDEEDLDS-QGSERRREYYR 395 3445666667777666666.6789*********9888765.678******96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (608 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1353 (0.0529654); expected 510.9 (0.02) Passed bias filter: 885 (0.0346447); expected 510.9 (0.02) Passed Vit filter: 78 (0.00305344); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.43s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 5788.78 // Query: FUN_001453-T1 [L=299] Description: FUN_001453 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-48 164.7 9.3 5.5e-48 164.4 9.3 1.1 1 Peptidase_C1 Papain family cysteine protease ------ inclusion threshold ------ 0.42 9.8 2.2 0.88 8.8 0.4 2.0 2 Peptidase_C1_2 Peptidase C1-like family Domain annotation for each model (and alignments): >> Peptidase_C1 Papain family cysteine protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 164.4 9.3 4.3e-52 5.5e-48 1 207 [. 54 274 .. 54 291 .. 0.88 Alignments for each domain: == domain 1 score: 164.4 bits; conditional E-value: 4.3e-52 Peptidase_C1 1 lpesvDwre....kggavtpvkdqg...sCGsCWafsavaalegrlaiktk..gklvslSeqelvdCdkeenegCnGGlmdkafeyikknggivte 87 +p+++Dwr+ k ++ + +++q+ CGsCWaf++++al++r++i++k + lS q+++ C + C+GG m +++y+k+ +gi +e FUN_001453-T1 54 IPTQLDWRAigegKINYASVTRNQHipqYCGSCWAFGTTSALSDRINIQRKnrWPSNLLSVQNVLACGN--AGTCHGGGMIVVYKYAKD-NGIPSE 146 699******98543333777899987779********************986656778*********75..679**************9.9***** PP Peptidase_C1 88 kdypYkakek..............gkCkkkkkkekevakikgyekvsendeealkkavakngPvsvaidasekdfqlYksGvyketecsktelnha 169 ++++Y+ak++ g+C++ ++ +k +k+++y++vs + +++++++ ++gP+++ i a+ ++++Y++G+y+e++ s +nh FUN_001453-T1 147 TCNNYQAKDQncslfnrcgtcttfGECHAISNYTK--WKVSEYGSVSGR--SKMMAEILARGPIACGIMATP-KLEKYEGGIYSEYNPSP-GINHV 236 *********99*******77777777776665544..899999999986..9999999999***********.5***********98886.9**** PP Peptidase_C1 170 vllvGygtengkdyWivkNsWgtdwgekGYiriargkn 207 + + G+g+e+g +yWiv+NsWgt wge+G+++i++++ FUN_001453-T1 237 ISVAGWGVEKGIEYWIVRNSWGTPWGEEGWLKIVTSQY 274 *********************************98765 PP >> Peptidase_C1_2 Peptidase C1-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.1 0.03 3.9e+02 62 81 .. 81 102 .. 61 113 .. 0.73 2 ? 8.8 0.4 6.9e-05 0.88 360 398 .. 234 270 .. 227 289 .. 0.80 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.03 Peptidase_C1_2 62 kqsGRCWlFaalnvl..Rlkll 81 + G CW F ++ +l R +++ FUN_001453-T1 81 QYCGSCWAFGTTSALsdRINIQ 102 4689******999874445554 PP == domain 2 score: 8.8 bits; conditional E-value: 6.9e-05 Peptidase_C1_2 360 tHamvltgvdvdddgkvtkwkvEnsWGedsGekGyfvms 398 +H + ++g v ++ ++ w v nsWG Ge+G++ + FUN_001453-T1 234 NHVISVAGWGV--EKGIEYWIVRNSWGTPWGEEGWLKIV 270 67777777777..667899***************98543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (299 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 668 (0.0261499); expected 510.9 (0.02) Passed bias filter: 407 (0.0159327); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2963.83 // Query: FUN_001454-T1 [L=300] Description: FUN_001454 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-10 41.0 0.0 7.2e-05 23.6 0.0 3.2 3 Glyoxalase Glyoxalase/Bleomycin resistance protein/Dioxyge 0.00026 21.8 0.0 0.4 11.5 0.0 2.6 2 Glyoxalase_4 Glyoxalase/Bleomycin resistance protein/Dioxyge 0.0041 17.6 0.1 1.4 9.5 0.0 2.6 3 DUF2059 Uncharacterized protein conserved in bacteria ( ------ inclusion threshold ------ 0.01 16.2 0.0 0.59 10.5 0.0 2.4 2 YycE-like_N YycE-like N-terminal domain 0.077 13.5 0.0 0.31 11.6 0.0 1.8 2 CppA_N CppA N-terminal 0.18 12.4 0.0 0.31 11.7 0.0 1.3 1 OMP_b-brl Outer membrane protein beta-barrel domain 0.19 12.0 0.0 7.9 6.8 0.0 2.8 3 Ble-like_N Bleomycin resistance protein-like N-terminal Domain annotation for each model (and alignments): >> Glyoxalase Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 4.7e-05 0.17 15 121 .] 9 123 .. 1 123 [. 0.77 2 ! 23.6 0.0 2e-08 7.2e-05 2 32 .. 153 183 .. 152 223 .. 0.87 3 ? 0.9 0.0 0.22 8.2e+02 101 118 .. 275 291 .. 224 294 .. 0.79 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4.7e-05 Glyoxalase 15 sldFYtevLGfklveetd.........ageegglrsafftaggrvlelllnetpppaaagegghhiafiafsvddvdaaydrlkaagveivrepgr 101 +++Y LG+ +++e +e+ ++s++ ++ + + +n++ +++ +++++ + i +s +dvd a l+++g e v p FUN_001454-T1 9 LVQWYGTRLGMSVIQEMQsdkelvqwiGFKEQPQSSFVEFRSSLQPSEPSNHSIKHYSHQPSSDVYWKIGLSLADVDTARSMLVSQG-EDVSLPRQ 103 58999999*****9999987777666644455555556666666666666666666666667899999*******************.77777777 PP Glyoxalase 102 hgwggrysffrDPdGnliel 121 + g+++++ DP+G+ +el FUN_001454-T1 104 FLNIGYMCHLNDPFGYSLEL 123 777777777*******9996 PP == domain 2 score: 23.6 bits; conditional E-value: 2e-08 Glyoxalase 2 idhvalrvgdleksldFYtevLGfklveetd 32 +++++lrv+++eksl+FY+ LG+kl+ + + FUN_001454-T1 153 VGQITLRVSNIEKSLAFYESGLGMKLLSRQT 183 67899**********************9988 PP == domain 3 score: 0.9 bits; conditional E-value: 0.22 Glyoxalase 101 rhgwggrysffrDPdGnl 118 +++++g + ++DPdG FUN_001454-T1 275 PEYNTGVLT-CKDPDGTS 291 456666666.*****976 PP >> Glyoxalase_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.0 0.00011 0.4 8 91 .. 4 96 .. 2 104 .. 0.85 2 ! 7.6 0.0 0.0018 6.6 2 45 .. 155 197 .. 154 226 .. 0.86 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00011 Glyoxalase_4 8 pdleralalwkrllGleetgdfrseeqnvdlafaklgdgsvevELiqpldgesplak.........hgeglhhlalwvddldaavarledqGf 91 p + +++++++ lG+++ ++ +s ++ v++ +k +s vE+ + l++++p + + ++l +d+d a l +qG FUN_001454-T1 4 PTITGLVQWYGTRLGMSVIQEMQSDKELVQWIGFKEQPQSSFVEFRSSLQPSEPSNHsikhyshqpSSDVYWKIGLSLADVDTARSMLVSQGE 96 66777899**********************999999998999*****9999977666667788666666789999999999999999999985 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0018 Glyoxalase_4 2 hvgiavpdleralalwkrllGleetgdfrseeqnvdlafaklgd 45 ++ + v ++e+ la+++ lG++ ++++++ + +dl+f+ + FUN_001454-T1 155 QITLRVSNIEKSLAFYESGLGMKLLSRQTIP-HKFDLYFLACTN 197 88999**********************9988.999999976555 PP >> DUF2059 Uncharacterized protein conserved in bacteria (DUF2059) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.3 0.0 0.0074 27 20 41 .. 6 27 .. 4 41 .. 0.87 2 ? -3.2 0.0 3.5 1.3e+04 13 22 .. 130 139 .. 128 146 .. 0.55 3 ! 9.5 0.0 0.00039 1.4 19 38 .. 162 181 .. 157 184 .. 0.84 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0074 DUF2059 20 lkalvaFYqSPlGqkllakepa 41 + +lv++Y + lG ++++ +++ FUN_001454-T1 6 ITGLVQWYGTRLGMSVIQEMQS 27 6789**************9986 PP == domain 2 score: -3.2 bits; conditional E-value: 3.5 DUF2059 13 ktfteaelka 22 k+f+ + ++a FUN_001454-T1 130 KNFSSERIQA 139 5555555544 PP == domain 3 score: 9.5 bits; conditional E-value: 0.00039 DUF2059 19 elkalvaFYqSPlGqkllak 38 +++ +aFY+S lG kll+ FUN_001454-T1 162 NIEKSLAFYESGLGMKLLSR 181 578889***********986 PP >> YycE-like_N YycE-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.039 1.4e+02 10 32 .. 6 28 .. 3 31 .. 0.84 2 ? 10.5 0.0 0.00016 0.59 8 28 .. 161 181 .. 158 195 .. 0.85 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.039 YycE-like_N 10 leevvefYeegLGLeklgeFedh 32 ++ +v+ Y + LG+++++e + + FUN_001454-T1 6 ITGLVQWYGTRLGMSVIQEMQSD 28 567899***********998776 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00016 YycE-like_N 8 dqleevvefYeegLGLeklge 28 ++e+ ++fYe gLG++ l + FUN_001454-T1 161 SNIEKSLAFYESGLGMKLLSR 181 58999************9987 PP >> CppA_N CppA N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1 3.6e+03 16 39 .. 11 34 .. 9 46 .. 0.75 2 ? 11.6 0.0 8.4e-05 0.31 5 30 .. 157 182 .. 154 189 .. 0.91 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1 CppA_N 16 dfyqetlGfkllseenalvvlgdw 39 ++y lG+ +++e ++ l +w FUN_001454-T1 11 QWYGTRLGMSVIQEMQSDKELVQW 34 6789999***99998775555555 PP == domain 2 score: 11.6 bits; conditional E-value: 8.4e-05 CppA_N 5 vlrvnnrelnidfyqetlGfkllsee 30 +lrv n e+ +fy lG+klls + FUN_001454-T1 157 TLRVSNIEKSLAFYESGLGMKLLSRQ 182 79*********************965 PP >> OMP_b-brl Outer membrane protein beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 8.4e-05 0.31 17 90 .. 68 147 .. 61 163 .. 0.70 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 8.4e-05 OMP_b-brl 17 eeeggvyvggglgnakfds.......dgdgtdsg.sgigiflgynfndnlgvegelsygsddstsvensdakentlt.lgvnl 90 + + vy + gl+ a++d+ +g+++ + ++i++ ++nd++g +el++++ + +++ +++++++ ++l FUN_001454-T1 68 QPSSDVYWKIGLSLADVDTarsmlvsQGEDVSLPrQFLNIGYMCHLNDPFGYSLELLQHDFQKNFS---SERIQAYLqQNLAL 147 4445677777777778887556666655566655699***********************999988...55544433234444 PP >> Ble-like_N Bleomycin resistance protein-like N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.084 3.1e+02 17 31 .. 11 26 .. 10 30 .. 0.81 2 ? 6.8 0.0 0.0022 7.9 9 28 .. 160 179 .. 156 183 .. 0.81 3 ? -3.0 0.0 2.5 8.9e+03 21 28 .. 247 254 .. 246 258 .. 0.74 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.084 Ble-like_N 17 aFYqdvLGfkine.mp 31 + Y+++LG +++ m+ FUN_001454-T1 11 QWYGTRLGMSVIQeMQ 26 67******99998565 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0022 Ble-like_N 9 vdDlerSkaFYqdvLGfkin 28 v +e+S aFY LG k+ FUN_001454-T1 160 VSNIEKSLAFYESGLGMKLL 179 5569*********9998875 PP == domain 3 score: -3.0 bits; conditional E-value: 2.5 Ble-like_N 21 dvLGfkin 28 ++LGf +n FUN_001454-T1 247 TALGFIVN 254 45999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (300 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 614 (0.024036); expected 510.9 (0.02) Passed bias filter: 563 (0.0220395); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2954.88 // Query: FUN_001455-T1 [L=653] Description: FUN_001455 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-33 113.6 5.1 1.2e-17 64.6 0.9 3.4 3 BTB BTB/POZ domain 4.8e-23 82.0 0.3 1.7e-19 70.4 0.0 2.3 2 Ras Ras family 1.2e-11 45.4 0.8 1.5e-10 41.8 0.3 2.7 2 Roc Ras of Complex, Roc, domain of DAPkinase 0.0028 17.9 0.5 3.1 8.2 0.1 2.9 2 BTB_KLHL33 Kelch-like protein 33-like, BTB/POZ domain ------ inclusion threshold ------ 0.13 12.9 0.3 0.67 10.6 0.1 2.4 2 BACK_BPM_SPOP BPM/SPOP, BACK domain 0.19 12.6 0.1 26 5.8 0.0 2.5 2 BTB_2 BTB/POZ domain 0.27 11.1 2.2 0.57 10.0 1.5 2.0 2 Clathrin-link Clathrin, heavy-chain linker 7.7 6.8 8.3 20 5.5 0.0 3.7 3 C2CH-3rd_BIRD-IDD BIRD-IDD transcription factor, third C2HC Domain annotation for each model (and alignments): >> BTB BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 0.0 5.5e-10 1.8e-06 4 44 .. 261 300 .. 258 312 .. 0.88 2 ! 20.3 0.1 2.1e-07 0.00068 47 106 .. 347 405 .. 334 408 .. 0.86 3 ! 64.6 0.9 3.7e-21 1.2e-17 5 108 .. 431 534 .. 428 536 .. 0.94 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 5.5e-10 BTB 4 lrekgklcDvtlvvedgkkfkahkavLaacSpyFkalfssk 44 l+++g Dv ++v+ g+ ++ah+avL+a+ p+F +lfs + FUN_001455-T1 261 LLHSGMCADVEFLVQ-GQPIQAHRAVLCAAAPVFAELFSAN 300 56677889*******.9*********************998 PP == domain 2 score: 20.3 bits; conditional E-value: 2.1e-07 BTB 47 eessvseieledvspedfealLefiYtgeleiseenveelLaladklqipslvkkceefl 106 + +v++i ++vs+++f +Lef+Y+g l++ e+ +el ++a+ lqi +lv+ +++ l FUN_001455-T1 347 CSFEVQVIIDNFVSHKTFMYILEFLYSGVLPV-EACTDELEEAAQDLQICNLVDYVTNVL 405 4556678889**********************.7899***************99988876 PP == domain 3 score: 64.6 bits; conditional E-value: 3.7e-21 BTB 5 rekgklcDvtlvvedgkkfkahkavLaacSpyFkalfsskeeeessvseieledvspedfealLefiYtgeleis.eenveelLaladklqipslv 99 + + ++D+++++e g+ + ahk +L a +++ a+f +++es v+++el+d ++++f ++Lef+Ytg+++ ++ +++ala+++ +p+l+ FUN_001455-T1 431 VNTQMFSDIVFKIE-GRIILAHKSYLVAQCEMMAAMFMAGHFKESGVQVVELKDTNFDAFLKVLEFLYTGQCPCLaLDDTLAVMALANFFCLPRLI 525 566789********.9************************9******************************99888999***************** PP BTB 100 kkceeflkk 108 ce+ ++k FUN_001455-T1 526 ALCEQVIVK 534 *****9876 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.1 0.00032 1 1 17 [. 16 32 .. 16 35 .. 0.92 2 ! 70.4 0.0 5.4e-23 1.7e-19 38 160 .. 71 211 .. 53 213 .. 0.93 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00032 Ras 1 klvlvGdsgvGKsslll 17 k+v++Gd+gvGKs l++ FUN_001455-T1 16 KCVVIGDTGVGKSRLIC 32 89***********9986 PP == domain 2 score: 70.4 bits; conditional E-value: 5.4e-23 Ras 38 tktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvk.kwleeikrvaeenvpivlvGnkvDlee.............. 118 + +++vdg +v l++wDT G +f+ r+ y++a++++l+++i+ ++f+nv+ w++eikr++++ +pi+lvG+++D + FUN_001455-T1 71 RGNFKVDGVDVALRLWDTFGDHEFN--RKFAYQHAHVVVLCFAINCPNTFKNVNaVWYSEIKRYCPR-TPIILVGTQSDWRMhfknsslvnvsrsl 163 457899******************8..6899**********************989**********5.*************99************* PP Ras 119 ......krevsteegeelakelglkfletSAktkenveeafeelvrei 160 v+ + g+++a+e+g+ ++e+S t +++++fe++vr++ FUN_001455-T1 164 skrmqdCSLVTPDMGRQVAREIGASYYEASVVTMWGIHDVFENAVRAA 211 *99988789***********************************9975 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.8 0.3 4.8e-14 1.5e-10 1 119 [] 16 146 .. 16 146 .. 0.66 2 ? -2.4 0.0 2.4 7.7e+03 57 85 .. 171 198 .. 150 230 .. 0.64 Alignments for each domain: == domain 1 score: 41.8 bits; conditional E-value: 4.8e-14 Roc 1 KvvllGdsgvGKtsllkr..fvedefdekekstigvdf....lskeltkikglend....kklkkiklniWDtaGqerfrslhplyyreaaaailv 86 K v++Gd+gvGK+ l+ + + ++ ++ v+f +++ ++++++ + ++ l++WDt G +f+ ++ y++a++++l+ FUN_001455-T1 16 KCVVIGDTGVGKSRLICAeaLGVGILPPQPSQKQHVHFptvfAIDQYHVSQEIRTRgnfkVDGVDVALRLWDTFGDHEFNR--KFAYQHAHVVVLC 109 789***********98652233333333333222222200002222222222222200013345799************95..79999*******9 PP Roc 87 fd...srssenlke.WlkelkevagkspvilvgnkiD 119 f ++++n++ W++e+k++++++p+ilvg++ D FUN_001455-T1 110 FAincPNTFKNVNAvWYSEIKRYCPRTPIILVGTQSD 146 987778899999655******************9987 PP == domain 2 score: -2.4 bits; conditional E-value: 2.4 Roc 57 klniWDtaGqerfrslhplyyreaaaail 85 +l D+ G + r++ +yy+++ + + FUN_001455-T1 171 SLVTPDM-GRQVAREIGASYYEASVVTMW 198 5555554.566777777888877766655 PP >> BTB_KLHL33 Kelch-like protein 33-like, BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.0 0.0 0.0024 7.6 18 55 .. 358 394 .. 350 401 .. 0.78 2 ! 8.2 0.1 0.00098 3.1 1 47 [. 465 513 .. 465 529 .. 0.76 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0024 BTB_KLHL33 18 tlsaseLeaLlsfaYsGtLtlgwdevfeiteaAlqyQv 55 ++s + + +l+f YsG L + + e+ eaA +Q+ FUN_001455-T1 358 FVSHKTFMYILEFLYSGVLPVE-ACTDELEEAAQDLQI 394 677788999**********987.566677777777776 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00098 BTB_KLHL33 1 mftsG.mrESqqeavaLrtlsaseLeaLlsfaYsGtLt.lgwdevfeit 47 mf+ G +ES ++v L+ + ++l+f Y+G+ l+ d + + FUN_001455-T1 465 MFMAGhFKESGVQVVELKDTNFDAFLKVLEFLYTGQCPcLALDDTLAVM 513 8999978****************************97534555555555 PP >> BACK_BPM_SPOP BPM/SPOP, BACK domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 3.6 1.2e+04 26 48 .. 113 134 .. 109 135 .. 0.64 2 ? 10.6 0.1 0.00021 0.67 5 28 .. 554 577 .. 550 592 .. 0.87 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 3.6 BACK_BPM_SPOP 26 aspnnlkavmatdgfehLkrscP 48 ++pn++k v + ++kr cP FUN_001455-T1 113 NCPNTFKNV-NAVWYSEIKRYCP 134 566666666.3445777777777 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00021 BACK_BPM_SPOP 5 tLaLAeqhhCsgLKdaCleFlasp 28 L+ A h+ s+L + C++F+++ FUN_001455-T1 554 YLVEAQVHNASQLEAWCIHFISTH 577 688899***************986 PP >> BTB_2 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.008 26 49 81 .. 360 389 .. 340 399 .. 0.84 2 ? 4.2 0.0 0.025 81 47 93 .. 483 527 .. 439 528 .. 0.80 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.008 BTB_2 49 spklFetiLnflrtggkLhepeevelkelleEl 81 s k F +iL+fl + g L+ + + +el+e + FUN_001455-T1 360 SHKTFMYILEFLYS-GVLPVE--ACTDELEEAA 389 5789**********.999986..7888877655 PP == domain 2 score: 4.2 bits; conditional E-value: 0.025 BTB_2 47 DRspklFetiLnflrtggkLhepeevelkelleElefygleelales 93 D + ++F ++L+fl t g+ ++ + + ++++ ++f+ l l ++ FUN_001455-T1 483 DTNFDAFLKVLEFLYT-GQCPCLALDDTLAVMALANFFCLPRL-IAL 527 566789**********.99999999999999999999999888.555 PP >> Clathrin-link Clathrin, heavy-chain linker # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 1.5 0.00018 0.57 3 15 .. 396 408 .. 396 409 .. 0.92 2 ? -2.8 0.0 1.8 5.8e+03 9 16 .. 594 601 .. 594 601 .. 0.85 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00018 Clathrin-link 3 nIIPYIlntLnNp 15 n++ Y++n+LnN+ FUN_001455-T1 396 NLVDYVTNVLNNV 408 8999********9 PP == domain 2 score: -2.8 bits; conditional E-value: 1.8 Clathrin-link 9 lntLnNpd 16 ++tL+N + FUN_001455-T1 594 TSTLKNIE 601 79****76 PP >> C2CH-3rd_BIRD-IDD BIRD-IDD transcription factor, third C2HC zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.0063 20 14 23 .. 144 153 .. 143 153 .. 0.92 2 ? 1.5 0.7 0.11 3.5e+02 4 9 .. 582 587 .. 580 588 .. 0.92 3 ? 2.0 0.3 0.074 2.4e+02 10 17 .. 609 616 .. 607 617 .. 0.91 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0063 C2CH-3rd_BIRD-IDD 14 eSDwKAHlKt 23 +SDw+ H+K+ FUN_001455-T1 144 QSDWRMHFKN 153 8*******96 PP == domain 2 score: 1.5 bits; conditional E-value: 0.11 C2CH-3rd_BIRD-IDD 4 CekCsK 9 C+kC+K FUN_001455-T1 582 CRKCPK 587 *****9 PP == domain 3 score: 2.0 bits; conditional E-value: 0.074 C2CH-3rd_BIRD-IDD 10 sYAVeSDw 17 +Y Ve+Dw FUN_001455-T1 609 WYIVEADW 616 6******* PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (653 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1259 (0.0492856); expected 510.9 (0.02) Passed bias filter: 813 (0.0318262); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 6345.66 // Query: FUN_001456-T1 [L=253] Description: FUN_001456 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-17 63.1 0.3 2.1e-16 60.6 0.2 2.2 2 RAWUL RAWUL domain RING finger- and WD40-associat 7.4e-10 39.0 9.1 7.4e-10 39.0 9.1 2.1 2 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 1.1e-09 38.4 8.7 1.1e-09 38.4 8.7 2.1 2 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 2.6e-08 34.3 12.0 1e-07 32.4 9.0 2.4 2 zf-C3HC4_4 zinc finger of C3HC4-type, RING 6.9e-07 29.6 3.3 6.9e-07 29.6 3.3 2.9 2 zf-RING_UBOX RING-type zinc-finger 1.7e-06 28.2 3.8 1.7e-06 28.2 3.8 1.8 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit 1.4e-05 25.5 7.5 1.4e-05 25.5 7.5 2.6 2 zf-RING_5 zinc-RING finger domain 5e-05 24.0 7.8 5e-05 24.0 7.8 2.5 2 zf-RING_2 Ring finger domain 0.0035 17.7 1.8 0.009 16.4 0.1 2.2 2 DUF3337 Domain of unknown function (DUF3337) 0.0042 17.4 4.0 0.01 16.2 4.0 1.6 1 zf-C3HC4_5 Zinc finger, C3HC4 type (RING finger) 0.0045 17.3 6.4 0.0045 17.3 6.4 2.4 2 Prok-RING_4 Prokaryotic RING finger family 4 0.0097 16.2 3.9 0.0097 16.2 3.9 2.1 3 zf-RING_6 zf-RING of BARD1-type protein ------ inclusion threshold ------ 0.015 15.5 4.0 0.027 14.7 4.0 1.5 1 TRAF3_RING TNF receptor-associated factor 2/3/5, RING d 0.017 15.2 3.3 0.04 14.0 3.3 1.6 1 zf-RING_16 RING/Ubox like zinc-binding domain 0.023 15.4 5.6 0.023 15.4 5.6 2.2 2 zf-rbx1 RING-H2 zinc finger domain 0.043 14.1 0.6 3.1 8.1 0.0 2.6 2 Rad60-SLD Ubiquitin-2 like Rad60 SUMO-like 0.083 13.4 3.3 0.25 11.9 3.3 1.8 1 zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H 0.25 12.0 8.3 0.11 13.1 3.1 2.5 2 zf-RING_10 zinc RING finger of MSL2 0.58 10.8 5.1 1.8 9.2 5.1 1.8 1 DUF1272 Protein of unknown function (DUF1272) 0.65 10.6 5.0 2.3 8.9 5.0 2.0 1 zf-RING-like RING-like domain 3.7 8.1 11.5 3.9 8.0 6.7 2.5 2 zf_RING-like RING zinc finger-like domain 4.9 7.4 9.5 0.12 12.6 1.5 2.4 3 YdjO Cold-inducible protein YdjO 8.6 7.1 12.0 3.1 8.5 8.4 2.2 2 Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING Domain annotation for each model (and alignments): >> RAWUL RAWUL domain RING finger- and WD40-associated ubiquitin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.1 2.4e+03 39 50 .. 74 86 .. 49 89 .. 0.70 2 ! 60.6 0.2 1.9e-19 2.1e-16 1 66 [] 182 247 .. 182 247 .. 0.92 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.1 RAWUL 39 evLpdsltL.dvv 50 e+L +++tL dv+ FUN_001456-T1 74 EMLRSDQTLqDVI 86 4599999997766 PP == domain 2 score: 60.6 bits; conditional E-value: 1.9e-19 RAWUL 1 rYlkcpanatVdhLkkyLalrlaleeeriykveilyegevLpdsltLdvvyikyWk..rnkPlelyYr 66 +Y++c++++t++ +kk+L ++l+l+ + ++ei+++ge++ +++tL++vy+++W+ + + l+l+Yr FUN_001456-T1 182 KYIRCSSRLTIAQVKKFLKVKLNLSTA--DQIEIMCNGEIMGKDHTLEFVYMTRWRikEGSLLTLQYR 247 7*************************9..7*************************7624557899997 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.0 9.1 6.6e-13 7.4e-10 1 40 [] 23 63 .. 23 63 .. 0.97 2 ? -2.8 0.1 7.7 8.5e+03 4 26 .. 162 166 .. 161 173 .. 0.54 Alignments for each domain: == domain 1 score: 39.0 bits; conditional E-value: 6.6e-13 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCikslle.snnvkCplC 40 C +C +l +p+t+++C+H+fC+sCi ++ + s ++Cp C FUN_001456-T1 23 CELCRGYLVKPTTITECLHTFCRSCIVKYFQdSDDNQCPIC 63 *******************************888888**** PP == domain 2 score: -2.8 bits; conditional E-value: 7.7 zf-C3HC4 4 CleelkepvtllpCgHsfCssCi 26 Cle C+ FUN_001456-T1 162 CLE------------------CL 166 444..................43 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.4 8.7 9.8e-13 1.1e-09 2 40 .] 23 63 .. 22 63 .. 0.95 2 ? -1.1 0.1 2.3 2.5e+03 4 12 .. 161 169 .. 160 174 .. 0.73 Alignments for each domain: == domain 1 score: 38.4 bits; conditional E-value: 9.8e-13 zf-C3HC4_2 2 CpiCldmlkdplvvtpCgHvfCqkCilraLeesn..eCPlC 40 C++C l +p ++t+C H+fC++Ci ++ ++s+ +CP+C FUN_001456-T1 23 CELCRGYLVKPTTITECLHTFCRSCIVKYFQDSDdnQCPIC 63 ******************************998777***** PP == domain 2 score: -1.1 bits; conditional E-value: 2.3 zf-C3HC4_2 4 iCldmlkdp 12 +Cl+ l+d FUN_001456-T1 161 VCLECLSDK 169 788888875 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 9.0 9e-11 1e-07 1 42 [] 23 63 .. 23 63 .. 0.96 2 ? 2.3 0.0 0.23 2.6e+02 20 28 .. 161 169 .. 158 179 .. 0.76 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 9e-11 zf-C3HC4_4 1 CpvCldyLekPvsi.eCGhsfClsCisslqkepdgesllCplC 42 C C yL kP++i eC h+fC+sCi ++ +++d++ Cp C FUN_001456-T1 23 CELCRGYLVKPTTItECLHTFCRSCIVKYFQDSDDN--QCPIC 63 99***********989*******************6..9**99 PP == domain 2 score: 2.3 bits; conditional E-value: 0.23 zf-C3HC4_4 20 fClsCissl 28 +Cl+C+s FUN_001456-T1 161 VCLECLSDK 169 7****9864 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 3.3 6.2e-10 6.9e-07 1 39 [] 23 61 .. 23 61 .. 0.91 2 ? 1.5 0.1 0.38 4.3e+02 21 30 .. 162 170 .. 160 186 .. 0.66 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 6.2e-10 zf-RING_UBOX 1 CpICleeftdP.lvlpCGHtfCreClwelskkekgkikCP 39 C C+ + +P ++++C HtfCr+C+ ++ ++++ +CP FUN_001456-T1 23 CELCRGYLVKPtTITECLHTFCRSCI-VKYFQDSDDNQCP 61 999********6668***********.8899999999999 PP == domain 2 score: 1.5 bits; conditional E-value: 0.38 zf-RING_UBOX 21 CreClwelsk 30 C eCl ++++ FUN_001456-T1 162 CLECL-SDKS 170 99999.2333 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 3.8 1.6e-09 1.7e-06 10 56 .. 19 63 .. 10 64 .. 0.90 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.6e-09 zf-Nse 10 islkcPltlqpfkePvtskkCnHvfekeaIlellkrkkkvkCPvvgC 56 ++c l + ++++P t ++C H+f ++ I+++++ ++ ++CP+ C FUN_001456-T1 19 SYITCELCRGYLVKPTTITECLHTFCRSCIVKYFQDSDDNQCPI--C 63 5689****************************************..6 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 7.5 1.2e-08 1.4e-05 2 42 .. 23 64 .. 20 65 .. 0.92 2 ? 0.9 0.2 0.57 6.3e+02 24 33 .. 161 170 .. 160 187 .. 0.75 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.2e-08 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll...eerqCpiCk 42 C C+ l ++ +t+C H+fC +C+ k++ +++qCpiC+ FUN_001456-T1 23 CELCRGYL--VKPTTITECLHTFCRSCIVKYFqdsDDNQCPICG 64 88888888..89999****************************6 PP == domain 2 score: 0.9 bits; conditional E-value: 0.57 zf-RING_5 24 fCeeClkkll 33 +C eCl+ ++ FUN_001456-T1 161 VCLECLSDKS 170 6999998877 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 7.8 4.5e-08 5e-05 2 43 .. 22 63 .. 21 64 .. 0.83 2 ? -1.3 0.1 3.5 3.9e+03 26 31 .. 162 167 .. 159 179 .. 0.54 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 4.5e-08 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst..CPlC 43 +C +C + + ++i+ +C H+f+++C+ k+++ s + CP+C FUN_001456-T1 22 TCELCR-GYLVKPTTIT-ECLHTFCRSCIVKYFQDSDDnqCPIC 63 799**6.5555555554.5****************99999**** PP == domain 2 score: -1.3 bits; conditional E-value: 3.5 zf-RING_2 26 hkeCld 31 + eCl+ FUN_001456-T1 162 CLECLS 167 334432 PP >> DUF3337 Domain of unknown function (DUF3337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.2 0.63 7.1e+02 93 134 .. 74 117 .. 52 150 .. 0.64 2 ! 16.4 0.1 8.1e-06 0.009 127 170 .. 202 247 .. 154 248 .. 0.84 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.63 DUF3337 93 rmLrvrKileyvaeklekktkeskpaseee..keeadkklkpee 134 +mLr + l+ v +k+ +e++ + e+e ++++ + k+ e FUN_001456-T1 74 EMLRSDQTLQDVISKILPCLQENEVKREKEfyEQQRLEDQKKIE 117 78888888888888887666555544433322222222222222 PP == domain 2 score: 16.4 bits; conditional E-value: 8.1e-06 DUF3337 127 dkklkpeeklellCndqvlppnmtLatvktfiW..kssgDlvLhYr 170 + +l +++e++Cn++++ + tL+ v + W k+++ l+L+Yr FUN_001456-T1 202 KLNLSTADQIEIMCNGEIMGKDHTLEFVYMTRWriKEGSLLTLQYR 247 4567889**************************4346777899998 PP >> zf-C3HC4_5 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 4.0 9.1e-06 0.01 23 49 .. 37 64 .. 21 65 .. 0.82 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 9.1e-06 zf-C3HC4_5 23 peCYhkmCesCvdRlfssG.PaqCPvag 49 +eC h+ C sC+ + f++ +qCP+ g FUN_001456-T1 37 TECLHTFCRSCIVKYFQDSdDNQCPICG 64 69**************875279***987 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 6.4 4e-06 0.0045 1 46 [] 23 73 .. 23 73 .. 0.83 2 ? 0.0 0.1 1 1.1e+03 20 29 .. 161 170 .. 158 176 .. 0.78 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 4e-06 Prok-RING_4 1 Cvlcgre.etkivlspCgHlvCkeC....fdssdfsaCPiCrrrvdaddpf 46 C lc+ + + C H C++C f+ sd + CPiC + +++pf FUN_001456-T1 23 CELCRGYlVKPTTITECLHTFCRSCivkyFQDSDDNQCPICGILIHETNPF 73 6666655233456899*********99999******************999 PP == domain 2 score: 0.0 bits; conditional E-value: 1 Prok-RING_4 20 vCkeCfdssd 29 vC eC + + FUN_001456-T1 161 VCLECLSDKS 170 9****98765 PP >> zf-RING_6 zf-RING of BARD1-type protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 3.9 8.8e-06 0.0097 3 46 .. 16 63 .. 14 68 .. 0.83 2 ? -3.1 0.0 9.6 1.1e+04 31 38 .. 162 169 .. 160 176 .. 0.73 3 ? -2.9 0.1 8.2 9.2e+03 5 12 .. 181 188 .. 179 194 .. 0.70 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 8.8e-06 zf-RING_6 3 rlekllrcsrctdilrepvclggcehifcsncisdcfg....sgcpvc 46 l+ + c c l +p + c h fc ci f cp+c FUN_001456-T1 16 ELNSYITCELCRGYLVKPTTITECLHTFCRSCIVKYFQdsddNQCPIC 63 5778899**************************988852222579999 PP == domain 2 score: -3.1 bits; conditional E-value: 9.6 zf-RING_6 31 csncisdc 38 c +c+sd FUN_001456-T1 162 CLECLSDK 169 88888885 PP == domain 3 score: -2.9 bits; conditional E-value: 8.2 zf-RING_6 5 ekllrcsr 12 k +rcs FUN_001456-T1 181 RKYIRCSS 188 58889974 PP >> TRAF3_RING TNF receptor-associated factor 2/3/5, RING domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 4.0 2.4e-05 0.027 1 32 [. 23 55 .. 23 64 .. 0.76 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.4e-05 TRAF3_RING 1 CekChLvLCsPkq.teCGhRfCesCmaaLLsss 32 Ce C L P teC h fC sC+ s FUN_001456-T1 23 CELCRGYLVKPTTiTECLHTFCRSCIVKYFQDS 55 99999999999754***********98766544 PP >> zf-RING_16 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 3.3 3.6e-05 0.04 6 51 .. 22 65 .. 17 71 .. 0.84 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 3.6e-05 zf-RING_16 6 kCayCelavkgrlflcgvCeHvlHasCareWfenddlaeCpsGCGc 51 +C +C + + +++ ++C H sC ++f+ d ++Cp CG+ FUN_001456-T1 22 TCELCRGYLVKPTTI-TECLHTFCRSCIVKYFQDSDDNQCPI-CGI 65 799998888877665.68****************999****8.776 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 5.6 2.1e-05 0.023 26 54 .. 33 63 .. 18 64 .. 0.86 2 ? -2.3 0.1 7.3 8.1e+03 30 30 .. 160 160 .. 135 174 .. 0.59 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 2.1e-05 zf-rbx1 26 pvvwGeCgHaFHlhCiskWlkt..rntCPlc 54 p+++ eC H+F Ci k+ + n+CP+c FUN_001456-T1 33 PTTITECLHTFCRSCIVKYFQDsdDNQCPIC 63 67789****************98999***** PP == domain 2 score: -2.3 bits; conditional E-value: 7.3 zf-rbx1 30 G 30 G FUN_001456-T1 160 G 160 2 PP >> Rad60-SLD Ubiquitin-2 like Rad60 SUMO-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.2 0.064 71 46 64 .. 105 123 .. 76 128 .. 0.82 2 ? 8.1 0.0 0.0028 3.1 19 58 .. 188 227 .. 174 233 .. 0.90 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.064 Rad60-SLD 46 FDGerLdpnstvedldied 64 ++ +rL++++++ed +i++ FUN_001456-T1 105 YEQQRLEDQKKIEDEEIQN 123 77899************97 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0028 Rad60-SLD 19 ptttvskLieayrekkgipaeeqvrLlFDGerLdpnstve 58 + t+ ++++ ++ k +++ +q++++ +Ge + +++t+e FUN_001456-T1 188 SRLTIAQVKKFLKVKLNLSTADQIEIMCNGEIMGKDHTLE 227 566999*******************************987 PP >> zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 3.3 0.00023 0.25 27 57 .. 34 63 .. 21 69 .. 0.85 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00023 zf-ANAPC11 27 lvlGkckhsfhlhcilkWletetskglcPmc 57 + +c h+f ci+k+++ + ++cP+c FUN_001456-T1 34 TTITECLHTFCRSCIVKYFQDS-DDNQCPIC 63 56789*************9865.5789***9 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 3.1 9.8e-05 0.11 2 43 .. 22 63 .. 21 81 .. 0.79 2 ? 0.8 0.2 0.68 7.6e+02 33 62 .. 139 166 .. 136 173 .. 0.68 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 9.8e-05 zf-RING_10 2 sCvvCgkLLvdPltpkeseCqHyvCrlCvgkkkk..lkpsCskC 43 +C C Lv+P+t +eC H Cr+C+ k + +C+ C FUN_001456-T1 22 TCELCRGYLVKPTTI--TECLHTFCRSCIVKYFQdsDDNQCPIC 63 7***********976..78*********9875441144567766 PP == domain 2 score: 0.8 bits; conditional E-value: 0.68 zf-RING_10 33 kkklkpsCskCkdykkyeenkqlrlllqCY 62 k+kl + C++ +++ + ++ q+ + l+C FUN_001456-T1 139 KEKLSADCNSKENF--HRDDPQIGVCLECL 166 66677777665555..45777888888884 PP >> DUF1272 Protein of unknown function (DUF1272) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 5.1 0.0016 1.8 7 48 .. 22 64 .. 16 68 .. 0.77 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0016 DUF1272 7 nCerCdkdlppdsaeariCsyEctfCaaCaeevl....envCPnCg 48 +Ce C l + + +i +tfC++C + + +n CP Cg FUN_001456-T1 22 TCELCRGYLVKPT---TITECLHTFCRSCIVKYFqdsdDNQCPICG 64 6999999998777...4555557******999883333478****8 PP >> zf-RING-like RING-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 5.0 0.002 2.3 1 43 [] 23 63 .. 23 63 .. 0.85 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.002 zf-RING-like 1 CeaCkeivtqGqrCsnedCnvrlHkdClekyfrtrrskkCpkC 43 Ce+C+ +++ + +C + + C+ kyf+ +++++Cp C FUN_001456-T1 23 CELCRGYLVKPTTIT--ECLHTFCRSCIVKYFQDSDDNQCPIC 63 777777777777766..89999999****************99 PP >> zf_RING-like RING zinc finger-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 6.7 0.0036 3.9 17 48 .] 35 63 .. 21 63 .. 0.80 2 ? 1.9 0.1 0.28 3.2e+02 24 34 .. 160 170 .. 159 196 .. 0.72 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0036 zf_RING-like 17 ACteCIcGvCreCvdalvseqsrgrrrgcPrC 48 teC+ +Cr+C+ ++ +++ ++cP C FUN_001456-T1 35 TITECLHTFCRSCIVKYFQDS---DDNQCPIC 63 569***********9999988...68899988 PP == domain 2 score: 1.9 bits; conditional E-value: 0.28 zf_RING-like 24 GvCreCvdalv 34 GvC eC + + FUN_001456-T1 160 GVCLECLSDKS 170 99999986443 PP >> YdjO Cold-inducible protein YdjO # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 2.5 2.8e+03 41 50 .. 22 31 .. 17 35 .. 0.75 2 ? 12.6 1.5 0.00011 0.12 16 46 .. 34 64 .. 30 72 .. 0.91 3 ? -3.1 0.2 8.3 9.3e+03 24 37 .. 144 155 .. 142 168 .. 0.60 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.5 YdjO 41 aCPlCkseMv 50 +C lC+ +v FUN_001456-T1 22 TCELCRGYLV 31 899**87665 PP == domain 2 score: 12.6 bits; conditional E-value: 0.00011 YdjO 16 tkvWeCtsedCngWmRdnfsfeeepaCPlCk 46 t++ eC + C++ + + f+ ++ ++CP+C+ FUN_001456-T1 34 TTITECLHTFCRSCIVKYFQDSDDNQCPICG 64 8899**************************8 PP == domain 3 score: -3.1 bits; conditional E-value: 8.3 YdjO 24 edCngWmRdnfsfe 37 dCn+ ++nf+ + FUN_001456-T1 144 ADCNS--KENFHRD 155 56665..5666544 PP >> Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 8.4 0.0028 3.1 1 35 [] 23 63 .. 23 63 .. 0.91 2 ? -1.9 0.1 4.8 5.4e+03 3 8 .. 161 166 .. 160 172 .. 0.58 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0028 Sina_RING 1 CpvCleymkppIlqCenGHliCssCrpkl......tkCptC 35 C +C y+ p + e H++C sC k ++Cp+C FUN_001456-T1 23 CELCRGYLVKPTTITECLHTFCRSCIVKYfqdsddNQCPIC 63 9**********9999999*********9877776668**99 PP == domain 2 score: -1.9 bits; conditional E-value: 4.8 Sina_RING 3 vCleym 8 vCle + FUN_001456-T1 161 VCLECL 166 555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (253 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2163 (0.0846741); expected 510.9 (0.02) Passed bias filter: 923 (0.0361323); expected 510.9 (0.02) Passed Vit filter: 92 (0.00360149); expected 25.5 (0.001) Passed Fwd filter: 25 (0.000978665); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 23 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2525.64 // Query: FUN_001457-T1 [L=99] Description: FUN_001457 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 522 (0.0204345); expected 510.9 (0.02) Passed bias filter: 353 (0.0138188); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1014.29 // Query: FUN_001458-T1 [L=98] Description: FUN_001458 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (98 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 740 (0.0289685); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 991.62 // Query: FUN_001459-T1 [L=267] Description: FUN_001459 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-16 60.2 0.1 5.6e-16 59.2 0.1 1.5 1 RAWUL RAWUL domain RING finger- and WD40-associat 2.1e-10 40.7 9.3 4.3e-10 39.7 9.3 1.5 1 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 4.1e-10 39.8 10.8 9.5e-10 38.7 10.8 1.7 1 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 8.3e-08 32.7 13.0 1.1e-07 32.3 10.6 2.2 2 zf-C3HC4_4 zinc finger of C3HC4-type, RING 3.8e-06 27.3 6.5 9.8e-06 26.0 6.5 1.7 1 zf-RING_UBOX RING-type zinc-finger 0.00022 21.9 8.8 0.00022 21.9 8.8 1.8 1 zf-RING_2 Ring finger domain 0.00024 21.4 7.0 0.00043 20.5 7.0 1.4 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit 0.00072 20.0 9.0 0.0015 19.0 9.0 1.6 1 zf-RING_5 zinc-RING finger domain 0.002 18.5 0.5 0.0063 16.9 0.5 1.9 1 DUF3337 Domain of unknown function (DUF3337) 0.0052 17.5 4.8 0.012 16.3 4.8 1.7 1 zf-rbx1 RING-H2 zinc finger domain 0.0088 16.6 0.5 0.027 15.0 0.5 1.8 1 zf-UDP Zinc-binding RING-finger ------ inclusion threshold ------ 0.015 15.1 0.1 0.037 13.8 0.1 1.6 2 Actin_micro Putative actin-like family 0.089 13.3 2.5 0.17 12.4 2.5 1.5 1 zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H 0.15 12.7 4.7 0.19 12.3 4.7 1.1 1 DDHD DDHD domain 0.16 12.6 4.6 0.32 11.6 4.6 1.5 1 zf-RING_10 zinc RING finger of MSL2 0.18 12.2 6.6 0.34 11.3 6.6 1.5 1 Prok-RING_4 Prokaryotic RING finger family 4 0.19 12.0 6.6 0.4 10.9 6.6 1.6 1 TRAF3_RING TNF receptor-associated factor 2/3/5, RING d 0.39 11.0 6.5 0.89 9.9 6.5 1.6 1 zf-RING_4 RING/Ubox like zinc-binding domain 0.44 11.2 7.0 0.94 10.1 7.0 1.5 1 DUF1272 Protein of unknown function (DUF1272) 1.7 9.3 9.1 7.2 7.2 9.1 2.2 1 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING 1.9 8.9 7.3 0.86 10.0 4.1 1.9 2 zf-RING_6 zf-RING of BARD1-type protein 2.3 8.8 6.8 6.7 7.3 6.8 1.9 1 zf_RING-like RING zinc finger-like domain 2.6 8.7 6.1 6.8 7.3 6.1 1.8 1 zf-C3H2C3 Zinc-finger 2.8 7.1 5.6 3.5 6.8 5.6 1.1 1 Presenilin Presenilin 3 8.6 7.6 8.4 7.1 6.7 2.2 2 Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING 4.6 7.7 6.9 15 6.1 6.9 1.9 1 zf-C3HC4_5 Zinc finger, C3HC4 type (RING finger) Domain annotation for each model (and alignments): >> RAWUL RAWUL domain RING finger- and WD40-associated ubiquitin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.2 0.1 5.7e-19 5.6e-16 1 66 [] 196 261 .. 196 261 .. 0.94 Alignments for each domain: == domain 1 score: 59.2 bits; conditional E-value: 5.7e-19 RAWUL 1 rYlkcpanatVdhLkkyLalrlaleeeriykveilyegevLpdsltLdvvyikyWk..rnkPlelyYr 66 +Y++c+++ t+ h+kkyL l+l+l++ +ve++++ge++ +++tL++v +++W+ n l+l+Yr FUN_001459-T1 196 KYIRCSSRTTIGHIKKYLKLKLKLSAV--DQVEVMCNGEIMGKDHTLEFVFMTRWRikGNTILTLQYR 261 7*************************7..8*************************6537889*****7 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.7 9.3 4.4e-13 4.3e-10 1 40 [] 1 42 [. 1 42 [. 0.94 Alignments for each domain: == domain 1 score: 39.7 bits; conditional E-value: 4.4e-13 zf-C3HC4_2 1 eCpiCldmlkdplvvtpCgHvfCqkCilraLeesn..eCPlC 40 +C++C+ l +p ++++C H+fC++Ci ++L+es+ CP+C FUN_001459-T1 1 MCELCKGYLIKPTTIAECLHTFCRSCIVQYLQESEenICPQC 42 8******************************9987547**** PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.7 10.8 9.7e-13 9.5e-10 1 40 [] 2 42 .. 2 42 .. 0.92 Alignments for each domain: == domain 1 score: 38.7 bits; conditional E-value: 9.7e-13 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCiksllesnnvk.CplC 40 C +C+ +l++p+t+++C+H+fC+sCi ++l++++++ Cp C FUN_001459-T1 2 CELCKGYLIKPTTIAECLHTFCRSCIVQYLQESEENiCPQC 42 *******************************555555**** PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.3 10.6 1.2e-10 1.1e-07 1 42 [] 2 42 .. 2 42 .. 0.97 2 ? -0.1 0.0 1.5 1.5e+03 3 9 .. 144 150 .. 143 151 .. 0.86 Alignments for each domain: == domain 1 score: 32.3 bits; conditional E-value: 1.2e-10 zf-C3HC4_4 1 CpvCldyLekPvsi.eCGhsfClsCisslqkepdgesllCplC 42 C C yL kP++i eC h+fC+sCi ++ +e++++ Cp+C FUN_001459-T1 2 CELCKGYLIKPTTIaECLHTFCRSCIVQYLQESEEN--ICPQC 42 99***********989******************96..***** PP == domain 2 score: -0.1 bits; conditional E-value: 1.5 zf-C3HC4_4 3 vCldyLe 9 vCl+yL FUN_001459-T1 144 VCLQYLR 150 8****96 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 6.5 1e-08 9.8e-06 1 39 [] 2 40 .. 2 40 .. 0.88 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 1e-08 zf-RING_UBOX 1 CpICleeftdP.lvlpCGHtfCreClwelskkekgkikCP 39 C C+ + +P ++ +C HtfCr+C+ ++ +e+++ CP FUN_001459-T1 2 CELCKGYLIKPtTIAECLHTFCRSCI-VQYLQESEENICP 40 99*********54459**********.8899999999998 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 8.8 2.2e-07 0.00022 3 43 .. 2 42 .. 1 43 [. 0.84 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 2.2e-07 zf-RING_2 3 CpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst..CPlC 43 C +C + + + ++i C H+f+++C+ ++l++s++ CP C FUN_001459-T1 2 CELC-KGYLIKPTTIAE-CLHTFCRSCIVQYLQESEEniCPQC 42 8899.566666666655.******************9****** PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 7.0 4.4e-07 0.00043 14 57 .] 2 43 .. 1 43 [. 0.96 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 4.4e-07 zf-Nse 14 cPltlqpfkePvtskkCnHvfekeaIlellkrkkkvkCPvvgCs 57 c l + ++ +P t +C H+f ++ I+++l++++++ CP+ Cs FUN_001459-T1 2 CELCKGYLIKPTTIAECLHTFCRSCIVQYLQESEENICPQ--CS 43 99999***********************************..86 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 9.0 1.5e-06 0.0015 2 42 .. 2 43 .. 1 44 [. 0.89 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 1.5e-06 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll...eerqCpiCk 42 C C l ++ + +C H+fC +C+ ++l ee+ Cp+C FUN_001459-T1 2 CELCKGYL--IKPTTIAECLHTFCRSCIVQYLqesEENICPQCS 43 66677777..788999****************9**********7 PP >> DUF3337 Domain of unknown function (DUF3337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.5 6.4e-06 0.0063 72 170 .. 169 261 .. 148 262 .. 0.75 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 6.4e-06 DUF3337 72 skleeeklpelenknsrLtanrmLrvrKileyvaeklekktkeskpaseeekeeadkklkpeeklellCndqvlppnmtLatvktfiWkssgD..l 165 ++ ++ek+pe +++ srL+++ + vrK + + ++ k+ + + + kl + +++e++Cn++++ + tL+ v + W+ +g+ l FUN_001459-T1 169 ERRKPEKTPESSTEDSRLSSSMWELVRKYIRCSSRTTIGHIKK--------YLKLKLKLSAVDQVEVMCNGEIMGKDHTLEFVFMTRWRIKGNtiL 256 4455668999998889999999988888776554443333332........233457899****************************98887335 PP DUF3337 166 vLhYr 170 +L+Yr FUN_001459-T1 257 TLQYR 261 56676 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 4.8 1.2e-05 0.012 26 54 .. 12 42 .. 1 43 [. 0.87 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 1.2e-05 zf-rbx1 26 pvvwGeCgHaFHlhCiskWlkt..rntCPlc 54 p+++ eC H+F Ci ++l++ +n CP c FUN_001459-T1 12 PTTIAECLHTFCRSCIVQYLQEseENICPQC 42 677899***************998999**99 PP >> zf-UDP Zinc-binding RING-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.5 2.7e-05 0.027 30 73 .. 15 59 .. 12 64 .. 0.77 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.7e-05 zf-UDP 30 cnecafpvcrpcy.eyerkdgnqsCPqCktrykrlkgsprvegde 73 + ec cr+c +y + ++ CPqC t + ++ +++d+ FUN_001459-T1 15 IAECLHTFCRSCIvQYLQESEENICPQCSTVIHETNPFEMLRSDQ 59 679999******63788888889*******988776666666655 PP >> Actin_micro Putative actin-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.1 3.8e-05 0.037 131 165 .. 5 39 .. 2 60 .. 0.90 2 ? -1.7 0.0 1.9 1.9e+03 73 109 .. 199 244 .. 127 249 .. 0.60 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 3.8e-05 Actin_micro 131 fKGiLllPesLalclglgiqsaivvseyekhttvl 165 +KG L++P+++a cl + s+iv +e+ +++ FUN_001459-T1 5 CKGYLIKPTTIAECLHTFCRSCIVQYLQESEENIC 39 8***********************99999988876 PP == domain 2 score: -1.7 bits; conditional E-value: 1.9 Actin_micro 73 rldklfksleeivgelelrvs..........keenlkpkdsFvslvf 109 r++++ ++ +i l+l+++ + ++ kd+ + +vf FUN_001459-T1 199 RCSSRT-TIGHIKKYLKLKLKlsavdqvevmCNGEIMGKDHTLEFVF 244 333332.3555555555444444555555545666777777777777 PP >> zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 2.5 0.00018 0.17 28 59 .. 14 44 .. 2 49 .. 0.85 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00018 zf-ANAPC11 28 vlGkckhsfhlhcilkWletetskglcPmcrq 59 + +c h+f ci+++l++ + ++ cP c FUN_001459-T1 14 TIAECLHTFCRSCIVQYLQE-SEENICPQCST 44 6789**************75.56789**9965 PP >> DDHD DDHD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 4.7 0.00019 0.19 119 206 .. 75 182 .. 25 195 .. 0.62 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00019 DDHD 119 g....ssllnrslglseeesaksadseqeeersseassaseesksaesssasssassssse....keteek................ssaseeekk 190 + +nrs +l++ +++ +++++e+ ++e+ ++ +++s++++++s +++++++ + ss+++++++ FUN_001459-T1 75 RervrEEEFNRSVRLGKRDTEGLKRKQKESDVDAEQPRKKHKNTSRRTTDHSDDSDGKQNFhrddP----QigvclqylrnhdeeevSSEDNSKRS 166 133335789****************99999999999999888888888888877777666544330....35666666655544434333333333 PP DDHD 191 eeeeeeeekakkseee 206 +e+++ ek+ +s++e FUN_001459-T1 167 PDERRKPEKTPESSTE 182 3333333333334444 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 4.6 0.00033 0.32 3 44 .. 2 43 .. 1 61 [. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00033 zf-RING_10 3 CvvCgkLLvdPltpkeseCqHyvCrlCvgk..kkklkpsCskCk 44 C C L +P+t eC H Cr+C+ + +++ + C++C FUN_001459-T1 2 CELCKGYLIKPTTI--AECLHTFCRSCIVQylQESEENICPQCS 43 999********876..89*********98822334456677776 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 6.6 0.00035 0.34 1 46 [] 2 52 .. 2 52 .. 0.79 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00035 Prok-RING_4 1 Cvlcgreetk.ivlspCgHlvCkeCf....dssdfsaCPiCrrrvdaddpf 46 C lc+ +k ++ C H C++C ++s+ + CP C + +++pf FUN_001459-T1 2 CELCKGYLIKpTTIAECLHTFCRSCIvqylQESEENICPQCSTVIHETNPF 52 6666666554146899*********64444889999**************9 PP >> TRAF3_RING TNF receptor-associated factor 2/3/5, RING domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 6.6 0.00041 0.4 1 33 [. 2 35 .. 2 44 .. 0.78 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00041 TRAF3_RING 1 CekChLvLCsPkq.teCGhRfCesCmaaLLssss 33 Ce C L P eC h fC sC+ L s FUN_001459-T1 2 CELCKGYLIKPTTiAECLHTFCRSCIVQYLQESE 35 999999999997537***********99887664 PP >> zf-RING_4 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 6.5 0.0009 0.89 19 43 .. 17 42 .. 2 45 .. 0.87 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0009 zf-RING_4 19 eCgyqiClfCyedile.eeegrCPgC 43 eC + +C+ C + l+ +ee++CP C FUN_001459-T1 17 ECLHTFCRSCIVQYLQeSEENICPQC 42 8*********9887764799****** PP >> DUF1272 Protein of unknown function (DUF1272) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 7.0 0.00096 0.94 8 48 .. 2 43 .. 1 48 [. 0.77 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00096 DUF1272 8 CerCdkdlppdsaeariCsyEctfCaaCaeevl....envCPnCg 48 Ce C+ l + + +i +tfC++C + l en+CP+C+ FUN_001459-T1 2 CELCKGYLIKPT---TIAECLHTFCRSCIVQYLqeseENICPQCS 43 999999888777...4555557******98888444468*****7 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 9.1 0.0073 7.2 2 49 .. 2 40 .. 1 52 [. 0.72 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0073 RING_XB3-XBAT31 2 CsiCferact.ieveeCgHqlCaqCalalcskkkkteaataskespaCP 49 C C + + ++ eC H++C +C+++ ++++++ CP FUN_001459-T1 2 CELCKGYLIKpTTIAECLHTFCRSCIVQYLQESEENI----------CP 40 778877665515689*************998875432..........33 PP >> zf-RING_6 zf-RING of BARD1-type protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 4.1 0.00088 0.86 10 48 .. 2 44 .. 1 49 [. 0.79 2 ? -1.4 0.1 3.2 3.1e+03 5 16 .. 195 206 .. 193 209 .. 0.79 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00088 zf-RING_6 10 csrctdilrepvclggcehifcsncisdcfgsg....cpvcyt 48 c c l +p + c h fc ci + + cp c t FUN_001459-T1 2 CELCKGYLIKPTTIAECLHTFCRSCIVQYLQESeeniCPQCST 44 88999*********************88764322233777766 PP == domain 2 score: -1.4 bits; conditional E-value: 3.2 zf-RING_6 5 ekllrcsrctdi 16 k +rcs t i FUN_001459-T1 195 RKYIRCSSRTTI 206 5899**987766 PP >> zf_RING-like RING zinc finger-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 6.8 0.0068 6.7 19 48 .] 16 42 .. 1 50 [. 0.89 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0068 zf_RING-like 19 teCIcGvCreCvdalvseqsrgrrrgcPrC 48 eC+ +Cr+C+ ++++e+ +++ cP+C FUN_001459-T1 16 AECLHTFCRSCIVQYLQES---EENICPQC 42 59*************9999...68889999 PP >> zf-C3H2C3 Zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 6.1 0.0069 6.8 1 34 [. 2 42 .. 2 43 .. 0.88 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0069 zf-C3H2C3 1 CdnCglkLdypfvaysCkHlvHakC.ad......eevCPkC 34 C+ C + L p C+H + + C ++ e++CP+C FUN_001459-T1 2 CELCKGYLIKPTTIAECLHTFCRSCiVQylqeseENICPQC 42 999**********************99766665578***** PP >> Presenilin Presenilin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 5.6 0.0035 3.5 231 314 .. 99 180 .. 54 216 .. 0.44 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0035 Presenilin 231 aeeeeaeeeeeaekkkeeeeeeskkeeseeeeseksassseeeeseete...................eeesaeeeseeeseeesseaessteess 307 ++++e++ ++e+ +kk+++++ +++++s++++ + + + +ee s+e++s+ + +++++ FUN_001459-T1 99 RKQKESDVDAEQPRKKHKNTSRRTTDHSDDSDGK--------------QnfhrddpqigvclqylrnhD-------EEEVSSEDNSKRSPDERRKP 173 1112222222222222222222222222222222..............122222232223322322110.......11111111111111111111 PP Presenilin 308 eekekee 314 e++ +++ FUN_001459-T1 174 EKTPESS 180 1111111 PP >> Sina_RING E3 ubiquitin-protein ligase sina/sinah, RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 6.7 0.0085 8.4 1 35 [] 2 42 .. 2 42 .. 0.82 2 ? -1.8 0.0 5.2 5.1e+03 3 9 .. 144 150 .. 143 152 .. 0.82 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0085 Sina_RING 1 CpvCleymkppIlqCenGHliCssCrpkl......tkCptC 35 C +C y+ p + e H++C sC + + Cp+C FUN_001459-T1 2 CELCKGYLIKPTTIAECLHTFCRSCIVQYlqeseeNICPQC 42 9************************9875444332359988 PP == domain 2 score: -1.8 bits; conditional E-value: 5.2 Sina_RING 3 vCleymk 9 vCl+y++ FUN_001459-T1 144 VCLQYLR 150 9***986 PP >> zf-C3HC4_5 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 6.9 0.015 15 23 47 .. 16 41 .. 1 45 [. 0.69 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.015 zf-C3HC4_5 23 peCYhkmCesC.vdRlfssGPaqCPv 47 +eC h+ C sC v+ l s + CP FUN_001459-T1 16 AECLHTFCRSCiVQYLQESEENICPQ 41 69*********445666777788885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (267 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2033 (0.079585); expected 510.9 (0.02) Passed bias filter: 925 (0.0362106); expected 510.9 (0.02) Passed Vit filter: 109 (0.00426698); expected 25.5 (0.001) Passed Fwd filter: 28 (0.0010961); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 26 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 2599.30 // Query: FUN_001460-T1 [L=201] Description: FUN_001460 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0042 16.7 2.5 0.0087 15.6 2.5 1.4 1 LptF_LptG Lipopolysaccharide export system permease LptF/Lpt ------ inclusion threshold ------ 0.1 13.3 4.6 0.16 12.7 0.7 2.3 2 Holin_2-3 Putative 2/3 transmembrane domain holin Domain annotation for each model (and alignments): >> LptF_LptG Lipopolysaccharide export system permease LptF/LptG # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 2.5 6.8e-07 0.0087 181 313 .. 37 194 .. 31 200 .. 0.78 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 6.8e-07 LptF_LptG 181 ekvitAksgeidkepdekkwrLengniyelnkdk.....kvsilsferyeidlsltpkdlktlsqdp............................. 242 +++i+A+s +i++++ + + L+ + ++ ++ ++++f r +i+l++tpk++k ++ ++ FUN_001460-T1 37 SEFIIANSVVIVSSNYVMSLWLYHSLRSRVRTQSyltlsYLRMEKFPRVKINLFKTPKSTKINKLKKlknkkkktkkeqetgfarishqhwfilke 132 57899*******99886666666666677777778999999**********************999999999999988777777766655555544 PP LptF_LptG 243 ....delslseLkesisrlkakgldarkyr.aelhrrlalPlavlilallalplglssrrsgkgag.lligillgfl 313 +el++s+L y+ +h+++++++++l ++l++l++ + + + +++ ++++ +++f+ FUN_001460-T1 133 adlySELKTSQL---------------VYKcWLYHQKITSAFSLLQFLLFGLCCPFQLNIYFYIFAmIMLANAVAFI 194 444444444444...............3444569**********************999999999877777777776 PP >> Holin_2-3 Putative 2/3 transmembrane domain holin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.1 0.028 3.6e+02 32 67 .. 47 82 .. 39 106 .. 0.79 2 ? 12.7 0.7 1.3e-05 0.16 6 41 .. 158 193 .. 153 197 .. 0.90 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.028 Holin_2-3 32 LvllaavlgywlDRvlFpyarpdsylvkdwkeekde 67 +v+ v++ wl +l + r +syl+ + + +++ FUN_001460-T1 47 IVSSNYVMSLWLYHSLRSRVRTQSYLTLSYLRMEKF 82 5566678999****************9888766665 PP == domain 2 score: 12.7 bits; conditional E-value: 1.3e-05 Holin_2-3 6 llalllllvialvsPqqLPvvlYklsLvllaavlgy 41 +ll +l+ +l P qL + Y +++++la +++ FUN_001460-T1 158 AFSLLQFLLFGLCCPFQLNIYFYIFAMIMLANAVAF 193 5689999************************99887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2239 (0.0876492); expected 510.9 (0.02) Passed bias filter: 737 (0.028851); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2037.86 // Query: FUN_001461-T1 [L=239] Description: FUN_001461 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.6e-18 65.2 0.5 1.7e-17 64.1 0.2 1.8 2 RAWUL RAWUL domain RING finger- and WD40-associat 2.8e-11 43.5 9.3 2.8e-11 43.5 9.3 2.5 3 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 5.2e-10 39.5 11.0 5.2e-10 39.5 11.0 2.7 3 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 2.6e-07 31.3 9.8 2.6e-07 31.3 9.8 2.6 3 zf-RING_2 Ring finger domain 2.3e-05 24.7 9.7 2.3e-05 24.7 9.7 2.3 2 zf-RING_5 zinc-RING finger domain 2.5e-05 24.8 8.4 0.0009 19.8 4.3 2.4 2 zf-RING_10 zinc RING finger of MSL2 0.00026 21.4 12.2 0.00059 20.3 9.8 2.5 2 zf-RING_UBOX RING-type zinc-finger 0.00032 21.2 8.9 0.00032 21.2 8.9 2.4 2 zf-C3HC4_4 zinc finger of C3HC4-type, RING 0.0034 17.6 9.9 0.0034 17.6 9.9 2.6 3 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) ------ inclusion threshold ------ 0.025 14.9 0.0 0.043 14.2 0.0 1.5 1 DUF3337 Domain of unknown function (DUF3337) 0.026 14.8 1.1 0.43 10.9 0.0 2.4 2 zf-UBP_var Variant UBP zinc finger 0.031 14.2 0.0 0.08 12.9 0.0 1.7 1 Mannitol_dh_C Mannitol dehydrogenase C-terminal domain 0.044 14.5 10.5 0.044 14.5 10.5 3.2 3 zf-rbx1 RING-H2 zinc finger domain 0.11 12.8 4.5 0.31 11.4 4.5 1.7 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit 0.19 12.1 12.0 0.15 12.4 6.0 2.6 2 zf-RING_4 RING/Ubox like zinc-binding domain 0.28 11.4 3.9 0.63 10.3 3.9 1.7 1 TRAF3_RING TNF receptor-associated factor 2/3/5, RING d 0.64 10.4 7.4 0.81 10.1 5.3 2.1 2 zf-RING_6 zf-RING of BARD1-type protein 1.1 9.9 8.5 0.4 11.3 5.0 2.1 2 DUF1272 Protein of unknown function (DUF1272) 2.8 8.6 8.1 8.8 7.0 8.1 2.0 1 zf-C3H2C3 Zinc-finger 7.5 7.2 14.7 5.7 7.6 10.8 2.7 2 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING Domain annotation for each model (and alignments): >> RAWUL RAWUL domain RING finger- and WD40-associated ubiquitin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 6.5 8.4e+03 35 51 .. 61 78 .. 43 79 .. 0.65 2 ! 64.1 0.2 1.4e-20 1.7e-17 1 66 [] 169 233 .. 169 233 .. 0.98 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 6.5 RAWUL 35 lyegevLpdsltL.dvvy 51 y+ ++++++ t+ ++vy FUN_001461-T1 61 SYPMNYISSDRTMqEIVY 78 355667888888866665 PP == domain 2 score: 64.1 bits; conditional E-value: 1.4e-20 RAWUL 1 rYlkcpanatVdhLkkyLalrlaleeeriykveilyegevLpdsltLdvvyikyWk.rnkPlelyYr 66 +Yl+ +++atV hLkk+La +l+l++ v+il+++e+L +++tL++++ ++W+ + Pl l+Yr FUN_001461-T1 169 KYLRLSSQATVLHLKKFLAKKLSLDDH--KDVDILCNDEILGKDHTLKFICVTRWRfKGCPLLLHYR 233 7*************************8..7*************************99999******8 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.5 9.3 2.2e-14 2.8e-11 2 40 .] 16 54 .. 15 54 .. 0.98 2 ? -1.4 0.1 2.4 3.1e+03 4 9 .. 150 155 .. 148 158 .. 0.71 3 ? -1.9 0.1 3.5 4.4e+03 20 39 .. 211 228 .. 210 228 .. 0.68 Alignments for each domain: == domain 1 score: 43.5 bits; conditional E-value: 2.2e-14 zf-C3HC4_2 2 CpiCldmlkdplvvtpCgHvfCqkCilraLeesneCPlC 40 C iC l d+ ++t+C H+fC++Ci + L+e+n CP+C FUN_001461-T1 16 CGICSGYLIDATTITECLHTFCRSCIVKHLQEENICPTC 54 *************************************** PP == domain 2 score: -1.4 bits; conditional E-value: 2.4 zf-C3HC4_2 4 iCldml 9 iC++ + FUN_001461-T1 150 ICMECY 155 788776 PP == domain 3 score: -1.9 bits; conditional E-value: 3.5 zf-C3HC4_2 20 HvfCqkCilraLeesneCPl 39 H+ C+ r+ + CPl FUN_001461-T1 211 HTLKFICVTRW--RFKGCPL 228 55556788888..6667885 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.5 11.0 4.1e-13 5.2e-10 1 40 [] 16 54 .. 16 54 .. 0.94 2 ? -1.0 0.1 1.9 2.4e+03 22 27 .. 151 156 .. 146 162 .. 0.68 3 ? -0.8 0.2 1.6 2.1e+03 19 38 .. 211 227 .. 201 228 .. 0.75 Alignments for each domain: == domain 1 score: 39.5 bits; conditional E-value: 4.1e-13 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCiksllesnnvkCplC 40 C iC +l++++t+++C+H+fC+sCi ++l+++ + Cp+C FUN_001461-T1 16 CGICSGYLIDATTITECLHTFCRSCIVKHLQEE-NICPTC 54 99*****************************55.55**** PP == domain 2 score: -1.0 bits; conditional E-value: 1.9 zf-C3HC4 22 CssCik 27 C +C++ FUN_001461-T1 151 CMECYR 156 666665 PP == domain 3 score: -0.8 bits; conditional E-value: 1.6 zf-C3HC4 19 HsfCssCiksllesnnvkCp 38 H++ + C++ + ++Cp FUN_001461-T1 211 HTLKFICVTRWRF---KGCP 227 7777788888877...4577 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 9.8 2e-10 2.6e-07 2 44 .] 15 55 .. 14 55 .. 0.92 2 ? -1.6 0.0 3.8 4.8e+03 5 30 .. 150 155 .. 145 162 .. 0.63 3 ? -0.9 0.2 2.3 3e+03 23 33 .. 211 221 .. 199 228 .. 0.55 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 2e-10 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsstCPlCr 44 +C iC + + ++++i+ C H+f+++C+ k+l++++ CP+C+ FUN_001461-T1 15 TCGIC-SGYLIDATTITE-CLHTFCRSCIVKHLQEENICPTCK 55 7****.799898888877.***********************6 PP == domain 2 score: -1.6 bits; conditional E-value: 3.8 zf-RING_2 5 iCleeleeeekvivlpCgHvfhkeCl 30 i + eC+ FUN_001461-T1 150 I--------------------CMECY 155 3....................44443 PP == domain 3 score: -0.9 bits; conditional E-value: 2.3 zf-RING_2 23 HvfhkeCldkw 33 H++ C+ +w FUN_001461-T1 211 HTLKFICVTRW 221 33334455555 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 9.7 1.8e-08 2.3e-05 2 42 .. 16 55 .. 15 56 .. 0.95 2 ? -0.3 0.1 1.2 1.5e+03 24 30 .. 150 156 .. 129 163 .. 0.73 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 1.8e-08 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll.eerqCpiCk 42 C +C+ l + +t+C H+fC +C+ k l ee+ Cp+Ck FUN_001461-T1 16 CGICSGYL--IDATTITECLHTFCRSCIVKHLqEENICPTCK 55 9*******..9*****************99998********8 PP == domain 2 score: -0.3 bits; conditional E-value: 1.2 zf-RING_5 24 fCeeClk 30 +C eC+ FUN_001461-T1 150 ICMECYR 156 4555544 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 4.3 7.1e-07 0.0009 2 49 .. 15 62 .. 14 74 .. 0.85 2 ! 6.5 0.1 0.0098 13 38 64 .. 128 157 .. 118 162 .. 0.78 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 7.1e-07 zf-RING_10 2 sCvvCgkLLvdPltpkeseCqHyvCrlCvgkkkklkpsCskCk..dykky 49 +C +C+ L d +t +eC H Cr+C+ k+ + + C++Ck +++y FUN_001461-T1 15 TCGICSGYLIDATTI--TECLHTFCRSCIVKHLQEENICPTCKivIHHSY 62 7**********7765..79***********************96544555 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0098 zf-RING_10 38 psCskCk...dykkyeenkqlrlllqCYkk 64 +sC++ + d + + ++q+++ ++CY+ FUN_001461-T1 128 SSCTSNEkedDQDYHRGDEQVAICMECYRA 157 667666567566677889**********96 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 9.8 4.6e-07 0.00059 1 39 [] 16 52 .. 16 55 .. 0.82 2 ? 0.5 0.0 0.72 9.1e+02 3 9 .. 150 156 .. 149 169 .. 0.60 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 4.6e-07 zf-RING_UBOX 1 CpICleeftdP.lvlpCGHtfCreClwelskkekgkikCP 39 C IC + d ++++C HtfCr+C+ k+ +++ CP FUN_001461-T1 16 CGICSGYLIDAtTITECLHTFCRSCI---VKHLQEENICP 52 99****9*9996568***********...66666666666 PP == domain 2 score: 0.5 bits; conditional E-value: 0.72 zf-RING_UBOX 3 ICleeft 9 IC+e + FUN_001461-T1 150 ICMECYR 156 6666665 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 8.9 2.5e-07 0.00032 1 42 [] 16 54 .. 16 54 .. 0.90 2 ? -1.4 0.1 3 3.8e+03 20 24 .. 150 154 .. 146 158 .. 0.76 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 2.5e-07 zf-C3HC4_4 1 CpvCldyLekPvsi.eCGhsfClsCisslqkepdgesllCplC 42 C +C+ yL + ++i eC h+fC+sCi + +e++ Cp C FUN_001461-T1 16 CGICSGYLIDATTItECLHTFCRSCIVKHLQEENI----CPTC 54 99**********9979**********999887654....9988 PP == domain 2 score: -1.4 bits; conditional E-value: 3 zf-C3HC4_4 20 fClsC 24 +C++C FUN_001461-T1 150 ICMEC 154 68888 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 9.9 2.7e-06 0.0034 4 47 .. 15 59 .. 14 61 .. 0.89 2 ? 0.1 0.1 0.79 1e+03 24 31 .. 149 156 .. 147 164 .. 0.71 3 ? -1.9 0.0 3.3 4.2e+03 29 41 .. 217 228 .. 215 228 .. 0.79 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 2.7e-06 zf-C3HC4_3 4 eCviClerern.vvllpCgHlclCeeCaeklr.kkkkCpiCrqkie 47 +C iC ++ +++++C H+ +C++C k +++ Cp C+ i+ FUN_001461-T1 15 TCGICSGYLIDaTTITECLHT-FCRSCIVKHLqEENICPTCKIVIH 59 6******9888467889****.********999********98886 PP == domain 2 score: 0.1 bits; conditional E-value: 0.79 zf-C3HC4_3 24 clCeeCae 31 ++C+eC + FUN_001461-T1 149 AICMECYR 156 46777754 PP == domain 3 score: -1.9 bits; conditional E-value: 3.3 zf-C3HC4_3 29 CaeklrkkkkCpi 41 C +++ + k Cp+ FUN_001461-T1 217 CVTRW-RFKGCPL 228 88888.8899985 PP >> DUF3337 Domain of unknown function (DUF3337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 3.4e-05 0.043 126 170 .. 188 233 .. 160 234 .. 0.82 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 3.4e-05 DUF3337 126 adkklkpeeklellCndqvlppnmtLatvktfiWk.ssgDlvLhYr 170 ++ +l+ ++ +++lCnd++l + tL+ + + W+ ++ l LhYr FUN_001461-T1 188 KKLSLDDHKDVDILCNDEILGKDHTLKFICVTRWRfKGCPLLLHYR 233 4556778889*************************44558999998 PP >> zf-UBP_var Variant UBP zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.2 0.2 2.5e+02 31 45 .. 32 47 .. 24 57 .. 0.75 2 ? 10.9 0.0 0.00034 0.43 28 60 .. 148 184 .. 140 188 .. 0.89 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.2 zf-UBP_var 31 cLkcFlgfck.khael 45 cL++F c kh+++ FUN_001461-T1 32 CLHTFCRSCIvKHLQE 47 8888877776677664 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00034 zf-UBP_var 28 lfvcLkcFlgfck....khaelhskrtghpvfLnikr 60 + +c++c+++ +k ++++ ++++ +L++k+ FUN_001461-T1 148 VAICMECYRANGKyslkPLTRKYLRLSSQATVLHLKK 184 78***********999888999999999999**9998 PP >> Mannitol_dh_C Mannitol dehydrogenase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 6.3e-05 0.08 5 60 .. 2 57 .. 1 69 [. 0.87 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 6.3e-05 Mannitol_dh_C 5 yeerKlriLNggHailaYlgalagyqtiheamkdeeiraavkkvleeevapllakv 60 y++ Klr LN+ + g+l +++ti e+++ +vk++ ee++ p+ ++v FUN_001461-T1 2 YQTLKLRELNAFITCGICSGYLIDATTITECLHTFCRSCIVKHLQEENICPTCKIV 57 8999*******999999***************999999999999999999999983 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 10.5 3.4e-05 0.044 28 55 .] 28 55 .. 15 55 .. 0.89 2 ? -2.7 0.1 8.3 1.1e+04 2 2 .. 147 147 .. 126 158 .. 0.53 3 ? 2.7 0.1 0.16 2.1e+02 33 53 .. 210 228 .. 187 229 .. 0.77 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.4e-05 zf-rbx1 28 vwGeCgHaFHlhCiskWlktrntCPlcr 55 ++ eC H+F Ci k l+++n CP+c+ FUN_001461-T1 28 TITECLHTFCRSCIVKHLQEENICPTCK 55 5679***********************6 PP == domain 2 score: -2.7 bits; conditional E-value: 8.3 zf-rbx1 2 t 2 + FUN_001461-T1 147 Q 147 1 PP == domain 3 score: 2.7 bits; conditional E-value: 0.16 zf-rbx1 33 gHaFHlhCiskWlktrntCPl 53 H+ + C+++W + CPl FUN_001461-T1 210 DHTLKFICVTRWRFK--GCPL 228 699999******543..6776 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 4.5 0.00024 0.31 12 56 .. 14 54 .. 5 55 .. 0.88 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00024 zf-Nse 12 lkcPltlqpfkePvtskkCnHvfekeaIlellkrkkkvkCPvvgC 56 ++c + ++ + t ++C H+f ++ I+++l ++++ CP C FUN_001461-T1 14 ITCGICSGYLIDATTITECLHTFCRSCIVKHL--QEENICPT--C 54 6899999999999999****************..88889998..7 PP >> zf-RING_4 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 6.0 0.00011 0.15 19 44 .. 31 55 .. 16 57 .. 0.91 2 ? 2.5 0.3 0.14 1.8e+02 10 30 .. 136 156 .. 128 161 .. 0.67 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00011 zf-RING_4 19 eCgyqiClfCyedileeeegrCPgCr 44 eC + +C+ C + l+ ee++CP C+ FUN_001461-T1 31 ECLHTFCRSCIVKHLQ-EENICPTCK 55 8*********999996.7*******9 PP == domain 2 score: 2.5 bits; conditional E-value: 0.14 zf-RING_4 10 etdkdllPCeCgyqiClfCye 30 e+d+d + + + iC++Cy FUN_001461-T1 136 EDDQDYHRGDEQVAICMECYR 156 555555555556679****96 PP >> TRAF3_RING TNF receptor-associated factor 2/3/5, RING domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 3.9 0.00049 0.63 13 29 .. 29 45 .. 16 56 .. 0.81 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00049 TRAF3_RING 13 qteCGhRfCesCmaaLL 29 teC h fC sC+ L FUN_001461-T1 29 ITECLHTFCRSCIVKHL 45 59**********97655 PP >> zf-RING_6 zf-RING of BARD1-type protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 5.3 0.00064 0.81 3 46 .. 9 54 .. 7 61 .. 0.84 2 ? -0.8 0.0 1.6 2e+03 15 45 .. 199 228 .. 189 235 .. 0.74 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00064 zf-RING_6 3 rlekllrcsrctdilrepvclggcehifcsncisdcfg..sgcpvc 46 l+ ++ c c+ l + + c h fc ci + cp c FUN_001461-T1 9 ELNAFITCGICSGYLIDATTITECLHTFCRSCIVKHLQeeNICPTC 54 5778899**************************9887522458888 PP == domain 2 score: -0.8 bits; conditional E-value: 1.6 zf-RING_6 15 dilrepvclggcehifcsncisdcfgsgcpv 45 dil + lg +h + c++ gcp+ FUN_001461-T1 199 DILCNDEILG-KDHTLKFICVTRWRFKGCPL 228 6666666664.57888888998888899996 PP >> DUF1272 Protein of unknown function (DUF1272) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 5.0 0.00031 0.4 8 47 .. 16 54 .. 5 57 .. 0.74 2 ? -2.6 0.1 6.7 8.5e+03 19 26 .. 145 152 .. 135 157 .. 0.60 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00031 DUF1272 8 CerCdkdlppdsaeariCsyEctfCaaCaeevl..envCPnC 47 C C+ l ++ +i +tfC++C ++l en+CP C FUN_001461-T1 16 CGICSGYLIDAT---TITECLHTFCRSCIVKHLqeENICPTC 54 666666665444...3444457*******99996669***** PP == domain 2 score: -2.6 bits; conditional E-value: 6.7 DUF1272 19 saeariCs 26 ++++ iC FUN_001461-T1 145 DEQVAICM 152 55555663 PP >> zf-C3H2C3 Zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 8.1 0.0069 8.8 1 35 [] 16 55 .. 16 55 .. 0.81 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0069 zf-C3H2C3 1 CdnCglkLdypfvaysCkHlvHakC.a....deevCPkCk 35 C +C + L C+H + + C + +e++CP+Ck FUN_001461-T1 16 CGICSGYLIDATTITECLHTFCRSCiVkhlqEENICPTCK 55 8888888877788889*********875554478*****7 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 10.8 0.0045 5.7 1 34 [. 15 49 .. 15 60 .. 0.80 2 ? -1.7 0.1 3.4 4.4e+03 46 51 .. 149 154 .. 128 159 .. 0.56 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0045 RING_XB3-XBAT31 1 lCsiCfera.ctieveeCgHqlCaqCalalcskkk 34 +C iC + ++ +++eC H++C +C++++ ++++ FUN_001461-T1 15 TCGICSGYLiDATTITECLHTFCRSCIVKHLQEEN 49 5999*9875267889*************9987753 PP == domain 2 score: -1.7 bits; conditional E-value: 3.4 RING_XB3-XBAT31 46 paCPfC 51 +C C FUN_001461-T1 149 AICMEC 154 344433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (239 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1157 (0.0452926); expected 510.9 (0.02) Passed bias filter: 661 (0.0258759); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2349.57 // Query: FUN_001462-T1 [L=253] Description: FUN_001462 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-19 68.2 0.5 9e-19 68.2 0.5 1.6 1 RAWUL RAWUL domain RING finger- and WD40-associat 3.1e-10 40.2 9.5 3.1e-10 40.2 9.5 2.2 3 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 1e-09 38.6 10.0 1e-09 38.6 10.0 1.9 2 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 2.7e-07 31.2 8.3 6.4e-07 30.0 8.3 1.7 1 zf-RING_2 Ring finger domain 8.9e-05 22.7 8.7 0.00021 21.5 8.7 1.6 1 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 0.00015 22.1 9.1 0.00039 20.8 9.1 1.7 1 zf-RING_UBOX RING-type zinc-finger 0.00022 21.9 6.0 0.00022 21.9 6.0 2.2 2 zf-rbx1 RING-H2 zinc finger domain 0.00024 21.5 12.4 0.0012 19.2 12.1 2.1 1 zf-RING_5 zinc-RING finger domain 0.0032 17.8 3.5 0.007 16.7 2.5 2.0 2 zf-RING_6 zf-RING of BARD1-type protein 0.0057 17.2 9.3 0.0057 17.2 9.3 1.7 1 zf-C3HC4_4 zinc finger of C3HC4-type, RING 0.0059 16.9 5.9 0.012 16.0 5.9 1.5 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit ------ inclusion threshold ------ 0.033 14.7 3.4 0.074 13.6 3.4 1.6 1 zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H 0.11 13.1 9.4 0.51 10.9 9.4 2.2 1 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING 0.14 12.5 0.7 0.21 11.9 0.1 1.7 2 DUF3337 Domain of unknown function (DUF3337) 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 UPF0261_C Uncharacterised protein family (UPF0261) C-t 0.22 11.8 5.1 0.51 10.6 5.1 1.6 1 TRAF3_RING TNF receptor-associated factor 2/3/5, RING d 0.31 11.5 8.2 1.7 9.1 7.0 2.5 2 zf-C3HC4_5 Zinc finger, C3HC4 type (RING finger) 0.41 11.1 10.8 0.94 9.9 9.2 2.2 2 Prok-RING_4 Prokaryotic RING finger family 4 0.87 10.2 10.7 0.26 11.9 7.0 2.1 2 zf-RING_10 zinc RING finger of MSL2 1.2 10.1 7.7 0.48 11.3 4.3 2.0 2 EHMT1-2_CRR Histone-lysine N-methyltransferase EHMT1/EHM Domain annotation for each model (and alignments): >> RAWUL RAWUL domain RING finger- and WD40-associated ubiquitin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.2 0.5 7.1e-22 9e-19 1 66 [] 176 240 .. 176 240 .. 0.98 Alignments for each domain: == domain 1 score: 68.2 bits; conditional E-value: 7.1e-22 RAWUL 1 rYlkcpanatVdhLkkyLalrlaleeeriykveilyegevLpdsltLdvvyikyWk.rnkPlelyYr 66 +Y++c+a++ V+ L+k+L+++l+++e+ +vei++++++ ++ t+++++i++W r+ P+ l+Yr FUN_001462-T1 176 KYIRCSARMMVAQLQKLLRMKLNIPED--KQVEIVCNDQIVHPFRTMKFIWISEWLnREPPMILHYR 240 7*************************9..7*************************88*********8 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.2 9.5 2.4e-13 3.1e-10 2 40 .] 19 57 .. 18 57 .. 0.98 2 ? -2.0 0.0 3.6 4.6e+03 4 13 .. 143 152 .. 142 154 .. 0.79 3 ? -2.4 0.0 4.7 6e+03 4 15 .. 208 219 .. 207 221 .. 0.79 Alignments for each domain: == domain 1 score: 40.2 bits; conditional E-value: 2.4e-13 zf-C3HC4_2 2 CpiCldmlkdplvvtpCgHvfCqkCilraLeesneCPlC 40 C +C + d+ ++t+C H+fC++Ci ++ + s++CP+C FUN_001462-T1 19 CSLCAGYFVDATTITECLHTFCKSCIVKYFQTSKNCPMC 57 *************************************** PP == domain 2 score: -2.0 bits; conditional E-value: 3.6 zf-C3HC4_2 4 iCldmlkdpl 13 +C+++l++ + FUN_001462-T1 143 LCVERLYESS 152 7999999864 PP == domain 3 score: -2.4 bits; conditional E-value: 4.7 zf-C3HC4_2 4 iCldmlkdplvv 15 +C d + p ++ FUN_001462-T1 208 VCNDQIVHPFRT 219 899999888766 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.6 10.0 7.9e-13 1e-09 1 40 [] 19 57 .. 19 57 .. 0.97 2 ? -3.3 0.0 9.4 1.2e+04 3 12 .. 208 217 .. 207 220 .. 0.74 Alignments for each domain: == domain 1 score: 38.6 bits; conditional E-value: 7.9e-13 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCiksllesnnvkCplC 40 C++C ++ +++t+++C+H+fC+sCi ++ + ++++Cp+C FUN_001462-T1 19 CSLCAGYFVDATTITECLHTFCKSCIVKYFQ-TSKNCPMC 57 *******************************.7788**** PP == domain 2 score: -3.3 bits; conditional E-value: 9.4 zf-C3HC4 3 iCleelkepv 12 +C +++ p+ FUN_001462-T1 208 VCNDQIVHPF 217 7999888776 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.0 8.3 5e-10 6.4e-07 3 43 .. 19 57 .. 17 58 .. 0.84 Alignments for each domain: == domain 1 score: 30.0 bits; conditional E-value: 5e-10 zf-RING_2 3 CpiCleeleeeekvivlpCgHvfhkeCldkwlrtsstCPlC 43 C++C + ++++i+ C H+f+k+C+ k+++ts++CP+C FUN_001462-T1 19 CSLCAGYF-VDATTITE-CLHTFCKSCIVKYFQTSKNCPMC 57 99**6555.66666655.*********************** PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 8.7 1.6e-07 0.00021 4 48 .. 18 63 .. 16 64 .. 0.88 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 1.6e-07 zf-C3HC4_3 4 eCviClerern.vvllpCgHlclCeeCaeklr.kkkkCpiCrqkies 48 C +C ++ +++++C H+ +C++C k+ ++k+Cp+C +i++ FUN_001462-T1 18 VCSLCAGYFVDaTTITECLHT-FCKSCIVKYFqTSKNCPMCSLQIHE 63 69999999777478889****.*******************999875 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 9.1 3e-07 0.00039 1 39 [] 19 55 .. 19 57 .. 0.88 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 3e-07 zf-RING_UBOX 1 CpICleeftdP.lvlpCGHtfCreClwelskkekgkikCP 39 C+ C f d ++++C HtfC++C+ k +++ CP FUN_001462-T1 19 CSLCAGYFVDAtTITECLHTFCKSCI---VKYFQTSKNCP 55 9********996568***********...77888888888 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 6.0 1.7e-07 0.00022 28 54 .. 31 57 .. 15 58 .. 0.88 2 ? -2.1 0.0 5.4 6.9e+03 41 47 .. 225 231 .. 199 233 .. 0.72 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 1.7e-07 zf-rbx1 28 vwGeCgHaFHlhCiskWlktrntCPlc 54 ++ eC H+F + Ci k+ +t+++CP+c FUN_001462-T1 31 TITECLHTFCKSCIVKYFQTSKNCPMC 57 5679*********************** PP == domain 2 score: -2.1 bits; conditional E-value: 5.4 zf-rbx1 41 iskWlkt 47 is+Wl++ FUN_001462-T1 225 ISEWLNR 231 7777775 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 12.1 9.8e-07 0.0012 2 41 .. 19 57 .. 18 58 .. 0.90 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 9.8e-07 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll.eerqCpiC 41 C+ C + + +t+C H+fC++C+ k++ ++ Cp+C FUN_001462-T1 19 CSLCAGYF--VDATTITECLHTFCKSCIVKYFqTSKNCPMC 57 77788888..88899*****************99******* PP >> zf-RING_6 zf-RING of BARD1-type protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 2.5 5.5e-06 0.007 8 47 .. 17 58 .. 10 76 .. 0.84 2 ? -1.5 0.0 2.6 3.3e+03 2 11 .. 187 196 .. 186 218 .. 0.68 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 5.5e-06 zf-RING_6 8 lrcsrctdilrepvclggcehifcsncisdcfgs..gcpvcy 47 + cs c+ + + + c h fc ci f + cp+c FUN_001462-T1 17 VVCSLCAGYFVDATTITECLHTFCKSCIVKYFQTskNCPMCS 58 67******************************75237****6 PP == domain 2 score: -1.5 bits; conditional E-value: 2.6 zf-RING_6 2 arlekllrcs 11 a+l+kllr FUN_001462-T1 187 AQLQKLLRMK 196 7899999864 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 9.3 4.5e-06 0.0057 1 42 [] 19 57 .. 19 57 .. 0.95 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 4.5e-06 zf-C3HC4_4 1 CpvCldyLekPvsi.eCGhsfClsCisslqkepdgesllCplC 42 C C y+ + ++i eC h+fC sCi ++ + +++ Cp+C FUN_001462-T1 19 CSLCAGYFVDATTItECLHTFCKSCIVKYFQTSKN----CPMC 57 99**********9979***************9998....9999 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 5.9 9e-06 0.012 11 57 .] 16 58 .. 7 58 .. 0.89 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 9e-06 zf-Nse 11 slkcPltlqpfkePvtskkCnHvfekeaIlellkrkkkvkCPvvgCs 57 + c l +f++ t ++C H+f k+ I++++ +++++CP+ Cs FUN_001462-T1 16 HVVCSLCAGYFVDATTITECLHTFCKSCIVKYF--QTSKNCPM--CS 58 5789999**************************..9999***9..86 PP >> zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 3.4 5.8e-05 0.074 29 59 .. 32 59 .. 17 65 .. 0.82 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 5.8e-05 zf-ANAPC11 29 lGkckhsfhlhcilkWletetskglcPmcrq 59 + +c h+f + ci+k+++t+ ++cPmc FUN_001462-T1 32 ITECLHTFCKSCIVKYFQTS---KNCPMCSL 59 578*************9876...47****64 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 9.4 0.0004 0.51 1 37 [. 18 55 .. 18 65 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.0004 RING_XB3-XBAT31 1 lCsiCfera.ctieveeCgHqlCaqCalalcskkkkte 37 +Cs C + ++ +++eC H++C +C+++ +++k+ FUN_001462-T1 18 VCSLCAGYFvDATTITECLHTFCKSCIVKYFQTSKNCP 55 699999865167889***************99987754 PP >> DUF3337 Domain of unknown function (DUF3337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 4 5.1e+03 123 142 .. 119 138 .. 103 147 .. 0.46 2 ? 11.9 0.1 0.00017 0.21 131 170 .. 199 240 .. 159 241 .. 0.80 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 4 DUF3337 123 keeadkklkpeeklellCnd 142 ++e+ k+ + +++ +l+ +d FUN_001462-T1 119 THENMKEREYSDYRNLYRDD 138 12222233334444444444 PP == domain 2 score: 11.9 bits; conditional E-value: 0.00017 DUF3337 131 kpee.klellCndqvlppnmtLatvktfiWkssg.DlvLhYr 170 pe+ ++e++Cndq+++p t++ + W + + ++LhYr FUN_001462-T1 199 IPEDkQVEIVCNDQIVHPFRTMKFIWISEWLNREpPMILHYR 240 455559************999999998888655426999998 PP >> UPF0261_C Uncharacterised protein family (UPF0261) C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00031 0.4 52 127 .. 68 145 .. 61 154 .. 0.82 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00031 UPF0261_C 52 ldavlDltttevadelvgGvlsagpdRleaaae.kgiPqvvsvGalDmvnfgardtvpekfke.Rklyehnpqvtlmr 127 ++ lD t+++++ +lv G+l+a+++R + e +g P v + ++ +++ ++++++ R+ly+ ++qv+l+ FUN_001462-T1 68 FNIRLDRTMQDIVGKLVPGILEAEEKRRREFYEsRGMPLVKPQADKENKKTTHENMKEREYSDyRNLYRDDEQVSLCV 145 56669*******************997766654279**9999888888888888888888865599999999999875 PP >> TRAF3_RING TNF receptor-associated factor 2/3/5, RING domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 5.1 0.0004 0.51 14 32 .. 33 51 .. 17 58 .. 0.78 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0004 TRAF3_RING 14 teCGhRfCesCmaaLLsss 32 teC h fC sC+ s FUN_001462-T1 33 TECLHTFCKSCIVKYFQTS 51 9**********98877554 PP >> zf-C3HC4_5 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 7.0 0.0013 1.7 23 48 .. 33 57 .. 18 60 .. 0.88 2 ? 0.2 0.0 0.79 1e+03 32 40 .. 143 151 .. 139 155 .. 0.82 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0013 zf-C3HC4_5 23 peCYhkmCesCvdRlfssGPaqCPva 48 +eC h+ C+sC+ + f++ ++CP+ FUN_001462-T1 33 TECLHTFCKSCIVKYFQTS-KNCPMC 57 69**************885.679975 PP == domain 2 score: 0.2 bits; conditional E-value: 0.79 zf-C3HC4_5 32 sCvdRlfss 40 Cv+Rl+ s FUN_001462-T1 143 LCVERLYES 151 5*****986 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.6 0.33 4.2e+02 18 24 .. 16 22 .. 14 25 .. 0.90 2 ? 9.9 9.2 0.00074 0.94 1 45 [. 19 66 .. 19 67 .. 0.75 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.33 Prok-RING_4 18 HlvCkeC 24 H+vC C FUN_001462-T1 16 HVVCSLC 22 *****99 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00074 Prok-RING_4 1 Cvlcgre.etkivlspCgHlvCkeCfds.sdfs.aCPiCrrrvdaddp 45 C+lc + C H Ck+C + + s CP+C ++ +++p FUN_001462-T1 19 CSLCAGYfVDATTITECLHTFCKSCIVKyFQTSkNCPMCSLQIHETQP 66 7888766344567899*********7652344458******9999987 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 7.0 0.0002 0.26 2 44 .. 18 58 .. 16 73 .. 0.86 2 ? -2.8 0.1 8.2 1e+04 45 58 .. 130 144 .. 114 147 .. 0.65 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0002 zf-RING_10 2 sCvvCgkLLvdPltpkeseCqHyvCrlCvgkkkklkpsCskCk 44 C+ C+ vd +t +eC H C++C+ k + +C++C FUN_001462-T1 18 VCSLCAGYFVDATT--ITECLHTFCKSCIVKYFQTSKNCPMCS 58 69999999999765..589***********************7 PP == domain 2 score: -2.8 bits; conditional E-value: 8.2 zf-RING_10 45 dykk.yeenkqlrll 58 dy++ y +++q++l FUN_001462-T1 130 DYRNlYRDDEQVSLC 144 454337777777765 PP >> EHMT1-2_CRR Histone-lysine N-methyltransferase EHMT1/EHMT2, Cys-rich region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 4.3 0.00038 0.48 42 92 .. 12 58 .. 7 60 .. 0.76 2 ? -0.9 0.1 2.3 3e+03 6 30 .. 172 199 .. 167 216 .. 0.60 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00038 EHMT1-2_CRR 42 rllkhncCpgC.GlfCtqGkfleCkkeeslkhlfhkeCalk.veekelcphcg 92 l+ h C+ C G+f + +++eC h+f k+C +k ++++ cp c+ FUN_001462-T1 12 DLNPHVVCSLCaGYFVDATTITEC------LHTFCKSCIVKyFQTSKNCPMCS 58 577888999885566666666666......69*******995678899***97 PP == domain 2 score: -0.9 bits; conditional E-value: 2.3 EHMT1-2_CRR 6 sidgklvgCsnkvek...eellrpserv 30 +++k ++Cs ++ ++llr+ ++ FUN_001462-T1 172 VLSKKYIRCSARMMVaqlQKLLRMKLNI 199 5566777777755441124455655555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (253 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1523 (0.0596203); expected 510.9 (0.02) Passed bias filter: 770 (0.0301429); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2467.54 // Query: FUN_001463-T1 [L=2269] Description: FUN_001463 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-65 221.6 5.6 3.5e-65 220.8 5.6 1.4 1 Beta-prop_LRRK2 LRRK2 beta propeller 1e-46 159.9 0.0 3.3e-46 158.3 0.0 1.8 2 Pkinase Protein kinase domain 7.7e-38 130.7 0.0 1.5e-37 129.8 0.0 1.4 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 3e-33 113.8 30.8 5.1e-08 33.0 1.4 7.0 6 LRR_8 Leucine rich repeat 2.9e-30 104.1 36.9 4.8e-06 27.1 0.1 8.6 8 LRR_4 Leucine Rich repeats (2 copies) 4e-28 98.6 11.5 2.6e-18 66.2 0.4 3.2 3 ARM_LRRK2 LRRK2 ARM repeat 5.6e-17 62.3 1.7 5.6e-17 62.3 1.7 3.2 3 ANK_LRRK2 LRRK2 ANK repeat 8e-15 55.5 0.1 2.3e-14 54.0 0.0 1.9 1 COR-A C-terminal of Roc, COR-A domain 1.5e-14 51.5 37.5 0.04 14.5 0.2 13.9 13 LRR_1 Leucine Rich Repeat 7.7e-13 49.2 0.0 1.6e-12 48.2 0.0 1.6 1 Roc Ras of Complex, Roc, domain of DAPkinase 4.6e-12 45.8 6.1 9.5e-06 25.1 0.2 3.1 2 LRR_14 Leucine-rich repeat region 6.3e-10 38.8 2.2 1.5e-09 37.6 1.7 1.8 2 WD40_2 WD40 repeated domain 3e-09 37.2 9.6 0.00018 21.6 1.8 3.8 4 LRR_9 Leucine-rich repeat 6.5e-08 32.9 0.0 1.7e-07 31.6 0.0 1.8 1 COR-B C-terminal of Roc, COR-B domain 2.9e-07 31.4 0.4 2.5e-06 28.4 0.2 2.6 2 Ank_2 Ankyrin repeats (3 copies) 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.3 1 Ras Ras family 8.7e-06 26.2 0.0 0.34 12.1 0.1 3.5 2 Ank_3 Ankyrin repeat 1.9e-05 25.2 0.4 0.23 12.4 0.0 4.2 3 Ank Ankyrin repeat 0.0021 18.8 0.3 0.14 12.9 0.0 3.3 3 AAA_22 AAA domain 0.0062 17.0 36.8 3.3 8.5 0.1 11.2 11 LRR_6 Leucine Rich repeat ------ inclusion threshold ------ 0.011 16.1 0.1 0.1 12.9 0.0 2.5 2 NACHT NACHT domain 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 NB-ARC NB-ARC domain 0.037 14.4 2.3 0.39 11.1 0.0 2.5 2 LRR_5 BspA type Leucine rich repeat region (6 copi 0.055 14.5 0.0 0.27 12.2 0.0 2.2 1 AAA_16 AAA ATPase domain 0.06 13.7 0.0 0.17 12.2 0.0 1.7 1 nSTAND_NTPase5 Novel STAND NTPase 5 0.11 13.3 0.1 3.4 8.5 0.0 3.0 3 WHD_HELB DNA helicase B winged helix domain 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 Septin Septin 0.13 12.0 0.2 12 5.5 0.0 2.8 3 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 0.16 12.2 0.1 0.44 10.8 0.1 1.6 1 DUF7334 Family of unknown function (DUF7334) 0.21 11.9 0.0 0.44 10.8 0.0 1.4 1 RsgA_GTPase RsgA GTPase 0.26 11.7 0.3 5.6 7.4 0.0 2.4 2 CSD_RNase_II CSD-like barrel domain 0.38 10.9 1.6 7.4 6.7 0.2 3.0 2 LRR_13 Disease resistance protein RPS4B-like, leuci 0.62 10.2 9.8 4.7 7.4 1.0 4.2 4 LRR_LRWD1 Leucine-rich repeat and WD repeat-containing 5.2 7.8 13.5 50 4.6 0.4 5.4 5 LRR_EndoS Endo-beta-N-acetylglucosaminidase EndoS LRR Domain annotation for each model (and alignments): >> Beta-prop_LRRK2 LRRK2 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 220.8 5.6 4.7e-68 3.5e-65 1 360 [] 1893 2244 .. 1893 2244 .. 0.87 Alignments for each domain: == domain 1 score: 220.8 bits; conditional E-value: 4.7e-68 Beta-prop_LRRK2 1 cLkrevvvpkgltveCmvvss...esskkaevWvgsGssek..gqlsaldletekvttqe...iddsrvlCLvlvqlpeekedwlvaGtqsg 84 cLkre++v+kg+tveCmvv++ ++ k+evWvgsG+s++ +q++++dl +++v+ i+d rv ++++v ++d+++aGt sg FUN_001463-T1 1893 CLKREIAVSKGQTVECMVVRHfeeDNVPKVEVWVGSGQSDDtsAQVAIIDLCDKGVEGCTgtyIRDRRVKSILAV-----DSDTVLAGTLSG 1979 *********************87777889**********8878********999988855555************.....899********* PP Beta-prop_LRRK2 85 slvvidtedkevkhslqkltDaVtsLlfhskskrskkknlllvGtAdGkLavyedsalkkedaaP.....vktlkvGnvstplmclse.svh 170 +++v+d+ ++++ s ++l++ V++L + ++ +++G+A+G+Lavy +s++k +da+ + + G vs+ + + ++ FUN_001463-T1 1980 TIWVFDAVNHKCEFSQPQLPNGVLCLKQY--------EDKVVAGLANGQLAVYGASSVKRKDAKAelldlCPSPSNGVVSQDECSVYPvACI 2063 **************************877........46799********************999665444556778887776665552445 PP Beta-prop_LRRK2 171 sldkktvwagcGtkilslssdfdveksidtkenqllskkssseanisrlvv.dkyiylskknspvvevWdkkseklkelidcaqllkeesak 261 kk++++gcG+++++l+ + +s +++ ++ + +++se+ + +++v ++ +++s+++s+v+ W+ + kl+ +dc+++l+++ + FUN_001463-T1 2064 AIGKKRIFCGCGNEVVVLQVN----ESGELEIENRWNGEEKSESVVLNIAVaSNLLWTSTRGSSVIKCWEHCKAKLVGHVDCVEILRDNGYS 2151 789***************765....4444444444456788**********7799*********************************9987 PP Beta-prop_LRRK2 262 erkeskeeaassarvkaLllqkntaLWiGtggGhillldlstrqllqvisrhcdsvRslasaqleslnrknvvlvlgrrlkesee...kkeq 350 + ++ arv +Lll ++ +LWiG+g+Gh++l+d s+r+l+++i+rh+++vR+l+ ++ ++++vl++ +++ e+++ +k++ FUN_001463-T1 2152 GD-------SRGARVVSLLLANR-TLWIGLGSGHMILVDSSSRKLVSIIRRHMAAVRCLVDTRSPDK-NNSLVLSGAMGFIERPGygsTKQT 2234 74.......678*******9876.9*************************************99666.6999********998875546666 PP Beta-prop_LRRK2 351 keeesvllvW 360 ++++++ lvW FUN_001463-T1 2235 NNTFGHALVW 2244 6778999999 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 6.4 4.8e+03 93 123 .. 1306 1337 .. 1299 1337 .. 0.84 2 ! 158.3 0.0 4.4e-49 3.3e-46 4 257 .. 1634 1883 .. 1632 1886 .. 0.88 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 6.4 Pkinase 93 galseeeakkilkqilegleylHseg.vvHrD 123 + ++e+e++ +++ ++++++ + g vvHrD FUN_001463-T1 1306 RLMQENELRMDDTEMEQAIKFMSEAGvVVHRD 1337 5688999999999999*******999678*99 PP == domain 2 score: 158.3 bits; conditional E-value: 4.4e-49 Pkinase 4 leklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkgalse 97 + lG+Gsfg+Vy+a+ +gk vA K+++ ++ ++ + +++E+ +l++l+hp i+ +++++ ++ l+lE+++ g+l +ll+ + al FUN_001463-T1 1634 DHLLGDGSFGVVYRAT--YNGKPVAAKVFHPRNVNHPY-RLLRQEVMFLRNLHHPSIISMVGTCVKPW--ALILELAPLGSLSTLLNSREALGR 1722 5789************..7*************999977.59***********************9875..5789******************** PP Pkinase 98 eeakkilkqilegleylHsegvvHrDlKpeNiLidekge.....lKitDFGlakelessskltsfvgtseYmAPEvl.kskkygkkvDvWslGv 185 +i+ q++egl++lH++ +v+rDlKp+NiLi + + Ki+D+G a+ + lt gt+ Y+APEv + +y ++vD++s G+ FUN_001463-T1 1723 GIQHRIALQVAEGLAFLHDNMIVYRDLKPHNILIFSLSIvnlinAKIADYGTARYATGCG-LTATEGTPGYRAPEVAkADASYNTEVDMYSFGM 1815 *********************************994332467779*************99.****************777899*********** PP Pkinase 186 ilyelltg.kppfsaekekekvekeldqlekilki.elkeklpepssiseeakdllkkllkkdpkkRltaeell 257 lyel+tg k pf+ + ++ +eld +++k l+ + + +++ dl+ ++l+ +pkkR ta+++ FUN_001463-T1 1816 FLYELVTGgKRPFE----DLRFGHELDA--AVMKGrALDPISSSDCKPWPDVADLIAHCLEPQPKKRATAQQAY 1883 ******95489***....5556677777..2333323344444455557899*******************986 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.8 0.0 2e-40 1.5e-37 5 257 .. 1635 1885 .. 1632 1886 .. 0.88 Alignments for each domain: == domain 1 score: 129.8 bits; conditional E-value: 2e-40 PK_Tyr_Ser-Thr 5 eklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkkke 97 + lG G+fG Vy++t++ +Va K+++ ++ ++ + + +e+ ++++l+hp i++++g c+ +p +++e+++ GsL++ L++ +e FUN_001463-T1 1635 HLLGDGSFGVVYRATYN------GKPVAAKVFHPRNVNHPYRLLRQEVMFLRNLHHPSIISMVGTCV--KPWALILELAPLGSLSTLLNS-RE 1718 679**************......99*******9999999999999**********************..8****************9999.79 PP PK_Tyr_Ser-Thr 98 klslkellklalqiAkGmeyLeskklvHrdlaarNvLvse.....kkvvkisDfGLardvekddyykkkekaklpikWmapEslkekk.ftsk 184 +l + ++alq+A+G+++L+++ +v rdl N+L+ + +ki+D+G ar+ + + ++ + apE+ k ++++ FUN_001463-T1 1719 ALGRGIQHRIALQVAEGLAFLHDNMIVYRDLKPHNILIFSlsivnLINAKIADYGTARYA----TGCGLTATEGTPGYRAPEVAKADAsYNTE 1807 99************************************99777644478**********9....4445556667789******998766**** PP PK_Tyr_Ser-Thr 185 sDvWsfGvllwEiftlgeepykgl.kneevlelleegerleqpe..nc..peelyelmkeCweedpeeRptfkelvee 257 D++sfG++l+E++t g++p+++l +e+ +++ +g+ l+ + +c ++++++l+++C e +p++R t ++ ++ FUN_001463-T1 1808 VDMYSFGMFLYELVTGGKRPFEDLrFGHELDAAVMKGRALDPISssDCkpWPDVADLIAHCLEPQPKKRATAQQAYSR 1885 ************************55678888889999887543114533579******************9987765 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.2 0.14 1.1e+02 26 41 .. 716 731 .. 709 738 .. 0.78 2 ! 33.0 1.4 6.8e-11 5.1e-08 2 61 .] 746 804 .. 745 804 .. 0.97 3 ! 20.2 0.1 6.9e-07 0.00052 27 61 .] 821 855 .. 816 855 .. 0.88 4 ! 25.3 7.4 1.8e-08 1.3e-05 1 61 [] 866 926 .. 863 926 .. 0.98 5 ! 13.2 0.0 0.00011 0.082 1 41 [. 945 985 .. 945 990 .. 0.94 6 ! 30.3 0.6 4.8e-10 3.6e-07 2 58 .. 994 1049 .. 993 1052 .. 0.95 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.14 LRR_8 26 nLkvLdLsnNllttls 41 ++ +dLs+N++++l+ FUN_001463-T1 716 TVRLIDLSRNNIESLR 731 5678999999999885 PP == domain 2 score: 33.0 bits; conditional E-value: 6.8e-11 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 ++++LdL++N+l++ +d+ + +++L+ +Ls+N+ +l p +f ++s+r L+Ls+N++ FUN_001463-T1 746 KVEKLDLNHNHLSDFPDELSEAMPKLQCVNLSHNEFCVL-PFSFITCTSVRLLNLSNNKI 804 689************************************.9*****************97 PP == domain 3 score: 20.2 bits; conditional E-value: 6.9e-07 LRR_8 27 LkvLdLsnNllttlspgafsg.LpsLrsLdLsgNrL 61 L++L+Ls+N+++ + p+++ + +p+L+sL+L gN++ FUN_001463-T1 821 LESLNLSHNEISGI-PEWLGNfFPALTSLYLAGNDI 855 99************.56666527***********97 PP == domain 4 score: 25.3 bits; conditional E-value: 1.8e-08 LRR_8 1 pnLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 ++Lr+LdLs+N+l+++++++ + + +L +L snN lt+l + + L++L+++ L+ N+L FUN_001463-T1 866 RQLRTLDLSNNHLKEIPPEFLSECLSLDTLVASNNGLTSLPESIAASLTNLKTIRLNKNKL 926 68**************************************9999***************98 PP == domain 5 score: 13.2 bits; conditional E-value: 0.00011 LRR_8 1 pnLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttls 41 pn++++dLssN l+++++ +++k+L L +N+++ ls FUN_001463-T1 945 PNVKVVDLSSNGLEEIPPPISWATQQMKELFLADNKIKKLS 985 799***********************************998 PP == domain 6 score: 30.3 bits; conditional E-value: 4.8e-10 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnN.llttlspgafsgLpsLrsLdLsg 58 +L++L Ls+N+l+ ++ g + l++L++LdLs+N +t l p+ + L+sL+ L Lsg FUN_001463-T1 994 QLERLALSDNNLKQVPSGIGE-LTSLMSLDLSRNpGITCL-PDEMGRLSSLWDLQLSG 1049 79*******************.************999999.9**************98 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.1 1.6 1.2e+03 4 19 .. 718 733 .. 716 738 .. 0.75 2 ! 21.1 0.3 5.2e-07 0.00039 2 33 .. 746 779 .. 745 786 .. 0.88 3 ? 4.2 0.9 0.1 77 1 16 [. 792 806 .. 792 815 .. 0.78 4 ! 27.1 0.1 6.4e-09 4.8e-06 3 41 .. 821 857 .. 819 862 .. 0.89 5 ! 16.1 0.7 1.9e-05 0.014 2 28 .. 867 895 .. 866 895 .. 0.87 6 ! 21.0 2.5 5.2e-07 0.00039 2 36 .. 891 926 .. 890 929 .. 0.86 7 ! 17.5 0.0 6.9e-06 0.0052 1 42 [. 945 986 .. 945 988 .. 0.86 8 ! 17.5 0.2 6.9e-06 0.0052 2 40 .. 994 1033 .. 993 1035 .. 0.91 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1.6 LRR_4 4 etLdLsnNritdidpl 19 + +dLs N+i+++ ++ FUN_001463-T1 718 RLIDLSRNNIESLRSI 733 5578999999988765 PP == domain 2 score: 21.1 bits; conditional E-value: 5.2e-07 LRR_4 2 nLetLdLsnNritdidp.ls.kLpnLetLdLsgN 33 ++e+LdL++N+++d + ls +p+L+ ++Ls+N FUN_001463-T1 746 KVEKLDLNHNHLSDFPDeLSeAMPKLQCVNLSHN 779 579***********99997735*********999 PP == domain 3 score: 4.2 bits; conditional E-value: 0.1 LRR_4 1 pnLetLdLsnNritdi 16 ++++ L+LsnN+i+ i FUN_001463-T1 792 TSVRLLNLSNNKIS-I 806 57899********9.3 PP == domain 4 score: 27.1 bits; conditional E-value: 6.4e-09 LRR_4 3 LetLdLsnNritdidp.lsk.LpnLetLdLsgNnkitdlsd 41 Le+L+Ls+N i+ i++ l++ +p L++L+L+gN d+ + FUN_001463-T1 821 LESLNLSHNEISGIPEwLGNfFPALTSLYLAGN----DIIN 857 9***************99999************....6543 PP == domain 5 score: 16.1 bits; conditional E-value: 1.9e-05 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetL 28 +L+tLdLsnN++++i+p ls + +L tL FUN_001463-T1 867 QLRTLDLSNNHLKEIPPefLSECLSLDTL 895 7****************976668888877 PP == domain 6 score: 21.0 bits; conditional E-value: 5.2e-07 LRR_4 2 nLetLdLsnNritdidp.ls.kLpnLetLdLsgNnki 36 +L tL snN +t++++ ++ +L+nL+t+ L+ N k+ FUN_001463-T1 891 SLDTLVASNNGLTSLPEsIAaSLTNLKTIRLNKN-KL 926 699**************85546*********666.66 PP == domain 7 score: 17.5 bits; conditional E-value: 6.9e-06 LRR_4 1 pnLetLdLsnNritdidp.ls.kLpnLetLdLsgNnkitdlsdL 42 pn+++ dLs+N +++i+p +s ++++L L++N ki++ls L FUN_001463-T1 945 PNVKVVDLSSNGLEEIPPpISwATQQMKELFLADN-KIKKLS-L 986 89****************63368999******776.**9996.5 PP == domain 8 score: 17.5 bits; conditional E-value: 6.9e-06 LRR_4 2 nLetLdLsnNritdidp.lskLpnLetLdLsgNnkitdls 40 +Le+L Ls+N+++ +++ ++ L++L +LdLs+N+ it l+ FUN_001463-T1 994 QLERLALSDNNLKQVPSgIGELTSLMSLDLSRNPGITCLP 1033 79***********99997777*************999885 PP >> ARM_LRRK2 LRRK2 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.2 0.4 3.5e-21 2.6e-18 342 457 .. 2 119 .. 1 168 [. 0.85 2 ! 24.6 0.9 1.3e-08 9.9e-06 92 180 .. 169 260 .. 154 266 .. 0.85 3 ! 14.9 0.5 1.2e-05 0.0087 144 217 .. 264 336 .. 253 349 .. 0.88 Alignments for each domain: == domain 1 score: 66.2 bits; conditional E-value: 3.5e-21 ARM_LRRK2 342 elhaknkevqeaacwalnnLllyqsklkekiede..dertPvhrqvmaamLlhssskevFqaaasalatlieqnskirslLLskGihvnvlelmkk 435 +h +++ev aac al++L+ + + e ++de ++ P+hr vmaa++lh +++ qaa ++la + + s +r+ L+skG+hv +++ mk+ FUN_001463-T1 2 STHYDKPEVLSAACNALKQLVDVCPYILELVGDEpgESTLPLHRCVMAALMLHLDDQDLCQAACQTLASMTNSSSSLRESLMSKGLHVHIIQAMKQ 97 5799***************************998445678******************************************************** PP ARM_LRRK2 436 hsssaevaesacklLkllfqgs 457 h + a v + +c+ L+ l + FUN_001463-T1 98 HRKDAGVQIWGCRALRGLSLSG 119 **************99875544 PP == domain 2 score: 24.6 bits; conditional E-value: 1.3e-08 ARM_LRRK2 92 dwevlgvhqqiLkvLslhkadvklvvvgLraLallLksdeitllvl.ee..eedvfslvveamktFpeseevqlqgCkaLqlLlekvseeql 180 + + gvh iLkv+ ++ ++v l v+L aL +l +++ei l++ + e+ ++++++am+ ++ ++q++g +q L +s+++ FUN_001463-T1 169 QSAIEGVHDMILKVMETYPDEVDLAEVSLEALGVLSAAQEIRELLVcSNcsEHSGVEIIFKAMERHRSERDIQQKGLILIQALAPLLSDDHC 260 556779***********************************8666514322567789********************999999999999885 PP == domain 3 score: 14.9 bits; conditional E-value: 1.2e-05 ARM_LRRK2 144 fslvveamktFpeseevqlqgCkaLqlLlekvseeqlveFvekkDhvvvLkvlkkFkdkeevvlqalkvllpLa 217 ++ v++am F++++ vq gC a+ + + ++ ++ v++ h + +l+ F ++ e+v a +++ La FUN_001463-T1 264 VKAVIDAMCEFSSDKGVQAEGCVAMFV-IAQIDRSKSEVLVNNCAHERLFYILELFAEEAELVYLASECIWYLA 336 5679*******************9865.678999999999**************************99999998 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.3 3.1 2.3e+03 9 37 .. 56 85 .. 48 89 .. 0.78 2 ? -0.4 0.2 1.8 1.3e+03 12 93 .. 191 240 .. 155 250 .. 0.62 3 ! 62.3 1.7 7.5e-20 5.6e-17 10 128 .. 321 436 .. 316 438 .. 0.95 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 3.1 ANK_LRRK2 9 kdqqlrklvckclaklald.sdlkeklLek 37 dq+l +++c++la +++ s l+e+l++k FUN_001463-T1 56 DDQDLCQAACQTLASMTNSsSSLRESLMSK 85 678999**********97615678877766 PP == domain 2 score: -0.4 bits; conditional E-value: 1.8 ANK_LRRK2 12 qlrklvckclaklaldsdlkeklLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvrEqdl 93 +l +++ ++ lg + +e l++ C s +e++ ++++ E+d+ FUN_001463-T1 191 DLAEVSLEA--------------------------------LGVLSAAQEIRELLVCSNCSEHSGVEIIFKAMERHRSERDI 240 334444444................................44444444455556666666666666666666666666555 PP == domain 3 score: 62.3 bits; conditional E-value: 7.5e-20 ANK_LRRK2 10 dqqlrklvckclaklaldsdlkeklLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvrEqdlrkaLavsvkrgd 105 + +l l+ +c+ la d +lk+++L aC+ g + +a+cl++ gadvn +s ++ C g+ ++v+ ll++g+ d+++aL++s+ g FUN_001463-T1 321 EAELVYLASECIWYLAFDRELKQSMLLSACAVGLLKLADCLIKKGADVNAGEGVNSPLCSACMNGK-DDVVKFLLTQGIT--DIQSALKLSLDMGH 413 567889999*****************************************************9998.89*********96..899*********** PP ANK_LRRK2 106 gevvsllLkkLgLDlansalcLg 128 g++v llL+ L+ D + + ++L+ FUN_001463-T1 414 GNIVGLLLQYLSHDKEAGIIALS 436 *****************999996 PP >> COR-A C-terminal of Roc, COR-A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.0 0.0 3.1e-17 2.3e-14 1 142 [] 1277 1424 .. 1277 1424 .. 0.91 Alignments for each domain: == domain 1 score: 54.0 bits; conditional E-value: 3.1e-17 COR-A 1 Pkswlevreelee..kkseknyisleeyreickenglkeee.eqdrllkfLhdlGvllyfqdde.elkdlviLkpeWlteavykvldskevlkk 90 P+++l++ + ++ ++ e ++++l+++r++++en+l+ ++ e+++++kf+ + Gv+++ +d + +l+dl +++p+Wl + ++ v+++k+ ++ FUN_001463-T1 1277 PQNFLSLLNIIRRqaQRLELPILTLANVRRLMQENELRMDDtEMEQAIKFMSEAGVVVHRDDPTcQLNDLLFVDPKWLFHRLAYVVTRKAGKNC 1370 677778888887766778899****************865548****************999557***************************99 PP COR-A 91 kGllkeedlkkiwkek.....ypaeehdellrlmekfelcyelekeeedtylvpqlL 142 +G+lk+++l+k+++e p+ + ++++rl +++ ++ +l++ +++lvp++L FUN_001463-T1 1371 DGILKHDELEKLLQEGsgddeLPSWLFPQMIRLFQHYCIALPLRD---NKFLVPSML 1424 9**************998888899999999999999999999999...99****987 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 1.2 8.9e+02 3 14 .. 718 729 .. 716 736 .. 0.76 2 ? 6.8 0.0 0.02 15 2 21 .. 747 765 .. 746 767 .. 0.83 3 ? 4.5 0.1 0.12 87 1 20 [. 770 788 .. 770 791 .. 0.79 4 ? 4.8 0.2 0.096 72 2 13 .. 794 805 .. 793 814 .. 0.76 5 ! 13.0 0.2 0.00016 0.12 2 23 .] 821 841 .. 820 841 .. 0.92 6 ? 2.5 0.1 0.56 4.2e+02 2 17 .. 845 859 .. 844 865 .. 0.76 7 ! 14.5 0.2 5.4e-05 0.04 1 21 [. 867 887 .. 867 889 .. 0.83 8 ? 3.4 0.0 0.28 2.1e+02 1 21 [. 891 910 .. 891 912 .. 0.86 9 ? 0.4 0.0 2.8 2.1e+03 1 13 [. 915 927 .. 915 935 .. 0.86 10 ? 5.9 0.0 0.041 31 1 20 [. 946 964 .. 946 966 .. 0.78 11 ? -1.1 0.0 9.3 7e+03 3 15 .. 972 984 .. 970 990 .. 0.77 12 ? 5.0 0.0 0.083 62 1 23 [] 994 1015 .. 994 1015 .. 0.85 13 ? 4.1 0.1 0.17 1.3e+02 1 23 [] 1017 1039 .. 1017 1039 .. 0.87 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 1.2 LRR_1 3 eeLdLsnNnlsg 14 + +dLs+Nn+++ FUN_001463-T1 718 RLIDLSRNNIES 729 779*******52 PP == domain 2 score: 6.8 bits; conditional E-value: 0.02 LRR_1 2 LeeLdLsnNnlsgllpeslg 21 +e+LdL++N+ls +p++l+ FUN_001463-T1 747 VEKLDLNHNHLS-DFPDELS 765 689********7.8888775 PP == domain 3 score: 4.5 bits; conditional E-value: 0.12 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L+ ++Ls+N + lp s+ FUN_001463-T1 770 KLQCVNLSHNEFC-VLPFSF 788 699*********6.666665 PP == domain 4 score: 4.8 bits; conditional E-value: 0.096 LRR_1 2 LeeLdLsnNnls 13 ++ L+LsnN++s FUN_001463-T1 794 VRLLNLSNNKIS 805 688********5 PP == domain 5 score: 13.0 bits; conditional E-value: 0.00016 LRR_1 2 LeeLdLsnNnlsgllpeslgnl 23 Le+L+Ls+N +s +pe+lgn+ FUN_001463-T1 821 LESLNLSHNEIS-GIPEWLGNF 841 9**********7.******985 PP == domain 6 score: 2.5 bits; conditional E-value: 0.56 LRR_1 2 LeeLdLsnNnlsgllp 17 L++L+L++N + lp FUN_001463-T1 845 LTSLYLAGNDII-NLP 859 99*********5.444 PP == domain 7 score: 14.5 bits; conditional E-value: 5.4e-05 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L++LdLsnN+l +++pe l+ FUN_001463-T1 867 QLRTLDLSNNHLKEIPPEFLS 887 59**********877777776 PP == domain 8 score: 3.4 bits; conditional E-value: 0.28 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L +L snN l+ +lpes++ FUN_001463-T1 891 SLDTLVASNNGLT-SLPESIA 910 688999******6.9999885 PP == domain 9 score: 0.4 bits; conditional E-value: 2.8 LRR_1 1 nLeeLdLsnNnls 13 nL+++ L+ N+l+ FUN_001463-T1 915 NLKTIRLNKNKLG 927 8**********95 PP == domain 10 score: 5.9 bits; conditional E-value: 0.041 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 n++++dLs+N l+ ++p+ + FUN_001463-T1 946 NVKVVDLSSNGLE-EIPPPI 964 6799********7.566554 PP == domain 11 score: -1.1 bits; conditional E-value: 9.3 LRR_1 3 eeLdLsnNnlsgl 15 +eL L++N++ l FUN_001463-T1 972 KELFLADNKIKKL 984 89*******9644 PP == domain 12 score: 5.0 bits; conditional E-value: 0.083 LRR_1 1 nLeeLdLsnNnlsgllpeslgnl 23 +Le+L Ls+Nnl + p+++g l FUN_001463-T1 994 QLERLALSDNNLK-QVPSGIGEL 1015 599*********5.999988865 PP == domain 13 score: 4.1 bits; conditional E-value: 0.17 LRR_1 1 nLeeLdLsnNnlsgllpeslgnl 23 +L +LdLs+N+ + lp++ g+l FUN_001463-T1 1017 SLMSLDLSRNPGITCLPDEMGRL 1039 699********988999988765 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.2 0.0 2.1e-15 1.6e-12 2 119 .] 1085 1205 .. 1084 1205 .. 0.82 Alignments for each domain: == domain 1 score: 48.2 bits; conditional E-value: 2.1e-15 Roc 2 vvllGdsgvGKtsllkrfvedefdekekstigvdflskelt.kikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd....sr 90 +v++G++g GKt+ll+++ e++ + ++ + + + k+++ ++k++ +++ ++ ++ WD+ G + ++ ++ ++++ ++++v+d + FUN_001463-T1 1085 LVVVGKAGRGKTTLLNQIQEENATGPHHDIMVREWHVKDTKaECKTC--HRRSVNYAITTWDFKGRDDLHNAYQCLLSSRTLYLVVYDvskgGT 1176 799******************99988777776666666543134443..3445578999*****************************854333 PP Roc 91 ssenlkeWlkelkevagkspvilvgnkiD 119 + + l+ Wl +++++a+++ v+lvg++ D FUN_001463-T1 1177 EIDGLRPWLLKINSYAPDASVMLVGTHKD 1205 457899********************998 PP >> LRR_14 Leucine-rich repeat region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 1.6 1.8e-07 0.00013 7 182 .. 776 960 .. 770 978 .. 0.71 2 ! 25.1 0.2 1.3e-08 9.5e-06 34 101 .. 980 1048 .. 968 1061 .. 0.71 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 1.8e-07 LRR_14 7 vfssaisll.pslssFqvLRVLdlegc..esseklslkhlgkLlhLRYLgLrntsiseLPeeIgkL.qfLqtLdlrgteikeLPssvvkLrkLmcL 98 + ++++ +l s+ + +R L+l++ + ++++ + ++ + L L+L++ +is +Pe +g+ L L l g++i +LP+ +Lr+L L FUN_001463-T1 776 LSHNEFCVLpFSFITCTSVRLLNLSNNkiSIGSSQHPNPEKRAIMLESLNLSHNEISGIPEWLGNFfPALTSLYLAGNDIINLPAFPLNLRQLRTL 871 555666666456678888999999877667777788888889999999999999999999999985378999999999999999999999999999 PP LRR_14 99 rvdegtr..l.PdgignLtsLeeLslvsv..dsssenfvkeLgkLteLrvLeikleewdeslekalvesLgkLqklqsLeilssgssle 182 ++++ + P+ + + sL L + +s e+++ L +L+ +r + kl+e++ + + + L L +++ ++++s+g ++ FUN_001463-T1 872 DLSNNHLkeIpPEFLSECLSLDTLVASNNglTSLPESIAASLTNLKTIRLNKNKLGERSAKKPFPIPRFLLTLPNVKVVDLSSNGLEEI 960 99875444552579999999999998888444444677776766666666555555555555555667788887777777776555544 PP == domain 2 score: 25.1 bits; conditional E-value: 1.3e-08 LRR_14 34 sseklslkhlgkLlhLRYLgLrntsiseLPeeIgkLqfLqtLdlrgt.eikeLPssvvkLrkLmcLrvd 101 + +klsl+ +k +L L L++ +++++P+ Ig+L +L Ldl+++ +i+ LP ++++L+ L L ++ FUN_001463-T1 980 KIKKLSLEGAKKWCQLERLALSDNNLKQVPSGIGELTSLMSLDLSRNpGITCLPDEMGRLSSLWDLQLS 1048 556777777777788888888888888888888888888888887754778888888888877777654 PP >> WD40_2 WD40 repeated domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 1.6 1.2e+03 31 56 .. 1917 1943 .. 1901 1950 .. 0.80 2 ! 37.6 1.7 2e-12 1.5e-09 97 297 .. 1965 2180 .. 1934 2187 .. 0.74 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.6 WD40_2 31 tslpqgylWvasga.esqmgqveivsl 56 ++p+ +Wv+sg+ + + qv+i+ l FUN_001463-T1 1917 DNVPKVEVWVGSGQsDDTSAQVAIIDL 1943 5678889*****951567899*99977 PP == domain 2 score: 37.6 bits; conditional E-value: 2e-12 WD40_2 97 akave.ptiClGledGsisvyksvdtakkvllql.vtPekspVlsLkhsssvLfaGLvnGtvavYarae......g.glWd..ee.sekvv... 175 + v+ +t+ G+ G i v+++v++ k+ + + P+ Vl+Lk+ ++ ++aGL+nG++avY ++ + +l d ++ s+ vv FUN_001463-T1 1965 LA-VDsDTVLAGTLSGTIWVFDAVNH--KCEFSQpQLPN--GVLCLKQYEDKVVAGLANGQLAVYGASSvkrkdaKaELLDlcPSpSNGVVsqd 2053 33.44499***************985..67666645564..6***********************76552100011234443322122333222 PP WD40_2 176 klGvlpvrsllaledtvWassgnqvtviete...tlsveqqleahqdegvsvshmvvaGgGvWiafssGssirLF.Ht..EtLehLqeiniatr 263 + v pv ++ + + ++ +gn+v+v++++ l++e++ + ++ + +v ++va +W + s i+ + H + h+ ++i r FUN_001463-T1 2054 ECSVYPVACIAIGKKRIFCGCGNEVVVLQVNesgELEIENRWNGEEKSESVVLNIAVASNLLWTSTRGSSVIKCWeHCkaKLVGHVDCVEIL-R 2146 34566***********************9873335899*************************99777778898834311334566666665.4 PP WD40_2 264 vtfllpgqkrvsvtsllvcqGlLlvGtslGiiva 297 + ++ + +v sll+++ L++G G +++ FUN_001463-T1 2147 DNGYSGDSRGARVVSLLLANRTLWIGLGSGHMIL 2180 56667777899***************99987765 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.3 0.00033 0.25 24 103 .. 698 784 .. 690 813 .. 0.74 2 ? 6.0 0.0 0.015 11 66 103 .. 821 858 .. 799 859 .. 0.92 3 ! 21.6 1.8 2.4e-07 0.00018 35 134 .. 836 935 .. 817 952 .. 0.81 4 ! 6.7 0.1 0.0089 6.7 44 124 .. 947 1027 .. 937 1034 .. 0.75 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00033 LRR_9 24 ldlrGykipvienlGatldqfdtidlsdneirkldg........fPllkrlktlllnnnrilrigegleevlPnleeliltknslqel 103 l+lr + i+n+ idls n+i l + + ++ +++ l ln n + ++l e++P+l+++ l++n++ l FUN_001463-T1 698 LGLRQRRKQSIKNILDN-ATVRLIDLSRNNIESLRSiadssqafLAYFSKVEKLDLNHNHLSDFPDELSEAMPKLQCVNLSHNEFCVL 784 55666666666666322.3456799999999998652222333346899*******************************99987655 PP == domain 2 score: 6.0 bits; conditional E-value: 0.015 LRR_9 66 lktlllnnnrilrigegleevlPnleeliltknslqel 103 l++l l n i i e l+++ P l++l l++n + +l FUN_001463-T1 821 LESLNLSHNEISGIPEWLGNFFPALTSLYLAGNDIINL 858 78999***************************998765 PP == domain 3 score: 21.6 bits; conditional E-value: 2.4e-07 LRR_9 35 enlGatldqfdtidlsdneirkldgfPl.lkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslkkltslsllrnpvtnke 129 e lG + ++ l+ n+i +l fPl l++l+tl l nn + i +++ +l++l+ ++n l++l + asl +l+++ l +n + ++ FUN_001463-T1 836 EWLGNFFPALTSLYLAGNDIINLPAFPLnLRQLRTLDLSNNHLKEIPPEFLSECLSLDTLVASNNGLTSLPE-SIAASLTNLKTIRLNKNKLGERS 930 55666666777888999**********87999**************9887777779****************.8899*************998877 PP LRR_9 130 dyrly 134 + + FUN_001463-T1 931 AKKPF 935 66655 PP == domain 4 score: 6.7 bits; conditional E-value: 0.0089 LRR_9 44 fdtidlsdneirkldg.fPl.lkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslkkltslsllrnp 124 +dls n + ++ + + +++k l+l +n+i +++ + + +le l l++n+l+++ + +l +l sl l rnp FUN_001463-T1 947 VKVVDLSSNGLEEIPPpISWaTQQMKELFLADNKIKKLSLEGAKKWCQLERLALSDNNLKQVPS--GIGELTSLMSLDLSRNP 1027 5677888888887753244425789999999999999998888889999999999999999865..55666666666666665 PP >> COR-B C-terminal of Roc, COR-B domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.6 0.0 2.3e-10 1.7e-07 3 145 .] 1441 1610 .. 1439 1610 .. 0.84 Alignments for each domain: == domain 1 score: 31.6 bits; conditional E-value: 2.3e-10 COR-B 3 elqlryeyeflpaGlfsrliVrlhkliege...............klvWrtGvlLkkdetralveadkedre....ikirvr.Geerkellsli 76 ++++y+++++p +l+srli+r+++++ + + W +G+ ++++e+ +v++ + ++ + i+ + + ls + FUN_001463-T1 1441 VVRRVYTMAYFPPSLWSRLIARMQTFVVNLyaeynaspeiprqpkAYQWNEGIHVHWSEQAFFVISHDLNNPdpdsVVIWTPhTKYGARILSHV 1534 6899********************9999989999**********99************999999999999878888888888569999****** PP COR-B 77 reeie.lihssfp....gleveelvpcpncek....kgsekpqtvsleklkeaeekgelelecdeskeevsvkeLlpd 145 ++++ +++ fp gl + vp++ + + + +t++le++ ++ ++ ++c ++k v++++++pd FUN_001463-T1 1535 VDHMDcMLEEYFPelwgGLDPQNGVPLIRKLAgcpiCQDASAHTFDLESISG--QNTDEFVMCPNTKLLVALRQIAPD 1610 *****999999992222345666677666555555555588999****9976..577889999999999999999886 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.4 0.2 3.3e-09 2.5e-06 3 82 .. 348 423 .. 344 431 .. 0.83 2 ? -1.1 0.0 5.6 4.2e+03 71 83 .. 2137 2149 .. 2130 2157 .. 0.59 Alignments for each domain: == domain 1 score: 28.4 bits; conditional E-value: 3.3e-09 Ank_2 3 lAakngnlelvklLl.egadanlqdkng.etaLhlAaknghleivklLlehgadvndnngrtaLhyAaesghleivklLlek 82 A++ g l+l++ L+ +gad+n +g +++L A++ng+ ++vk+Ll +g+ ++ ++aL ++ +gh +iv lLl++ FUN_001463-T1 348 SACAVGLLKLADCLIkKGADVNA--GEGvNSPLCSACMNGKDDVVKFLLTQGI-TD---IQSALKLSLDMGHGNIVGLLLQY 423 577889899******99999983..45568*******************9974.33...569******************76 PP == domain 2 score: -1.1 bits; conditional E-value: 5.6 Ank_2 71 ghleivklLlekg 83 gh+++v++L ++g FUN_001463-T1 2137 GHVDCVEILRDNG 2149 5666666665554 PP >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.0 0.0 2.6e-09 2e-06 2 122 .. 1085 1212 .. 1084 1235 .. 0.84 Alignments for each domain: == domain 1 score: 28.0 bits; conditional E-value: 2.6e-09 Ras 2 lvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevd.......gkevklqiwDTAGqerfralreayyrgaegillvyditsees.f 87 lv+vG+ g GK++ll + +++ + ++ + + ++k+++++ + ++ ++ wD G ++ ++ + +++ + l+vyd+++ + FUN_001463-T1 1085 LVVVGKAGRGKTTLLNQIQEENATGPHHDIMVREWHVKDTKAEcktchrrSVNYAITTWDFKGRDDLHNAYQCLLSSRTLYLVVYDVSKGGTeI 1178 8****************99988777766666566666665555444444367778999*****************************9986538 PP Ras 88 envkkwleeikrvaeenvpivlvGnkvDleekrev 122 + ++ wl +i+++a++ ++++lvG+ +D k+ v FUN_001463-T1 1179 DGLRPWLLKINSYAPD-ASVMLVGTHKDKIPKHRV 1212 8999***********5.9********997766655 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.1 0.1 0.00045 0.34 3 31 .] 343 370 .. 341 370 .. 0.94 2 ! 10.2 0.0 0.0019 1.5 3 27 .. 375 399 .. 375 403 .. 0.84 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00045 Ank_3 3 ntpLhlAarngrleivklLleklgadina 31 +++L A+ g l+++++L++ +gad+na FUN_001463-T1 343 QSMLLSACAVGLLKLADCLIK-KGADVNA 370 899******************.*****96 PP == domain 2 score: 10.2 bits; conditional E-value: 0.0019 Ank_3 3 ntpLhlAarngrleivklLleklga 27 n+pL A++ng+ ++vk+Ll + FUN_001463-T1 375 NSPLCSACMNGKDDVVKFLLTQGIT 399 688889**************95555 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.1 0.022 17 8 30 .. 348 370 .. 343 372 .. 0.85 2 ! 12.4 0.0 0.00031 0.23 3 28 .. 375 401 .. 375 406 .. 0.85 3 ? 0.6 0.0 1.8 1.3e+03 13 25 .. 2137 2149 .. 2132 2155 .. 0.82 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.022 Ank 8 lAaraghlevvklLLkhGAdvna 30 A+ g l+++ L+k+GAdvna FUN_001463-T1 348 SACAVGLLKLADCLIKKGADVNA 370 57778999*******88*****8 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00031 Ank 3 nTPLHlAaraghlevvklLLkhG.Adv 28 n+PL A+++g +vvk+LL +G d+ FUN_001463-T1 375 NSPLCSACMNGKDDVVKFLLTQGiTDI 401 79******************5585565 PP == domain 3 score: 0.6 bits; conditional E-value: 1.8 Ank 13 ghlevvklLLkhG 25 gh+++v++L ++G FUN_001463-T1 2137 GHVDCVEILRDNG 2149 9*******98555 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 4.1 3.1e+03 33 82 .. 7 58 .. 2 72 .. 0.79 2 ! 12.9 0.0 0.00019 0.14 5 33 .. 1082 1117 .. 1079 1176 .. 0.75 3 ? 1.3 0.0 0.77 5.8e+02 37 96 .. 1239 1307 .. 1214 1351 .. 0.83 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 4.1 AAA_22 33 ddsvvlvelpsstspkdllrellralglelek.elskeell.aalqealkal 82 +++v+ +++ + + d++ +l+ +g e+ + +l ++++ aal+ +l+++ FUN_001463-T1 7 KPEVLSAACNALKQLVDVCPYILELVGDEPGEsTLPLHRCVmAALMLHLDDQ 58 688999999999***************9888876777777666666666655 PP == domain 2 score: 12.9 bits; conditional E-value: 0.00019 AAA_22 5 agilvltGesGtGKTtllrrlleqldee.......d 33 + lv++G +G GKTtll++++e++ + FUN_001463-T1 1082 RMNLVVVGKAGRGKTTLLNQIQEENATGphhdimvR 1117 6689*******************9865555444440 PP == domain 3 score: 1.3 bits; conditional E-value: 0.77 AAA_22 37 vlvelpsst.spkdllrellralglelek.........elskeellaalqealkalaaravliiDEaqnl 96 vl +++++t + k+l++++l+ + + k +++ ll+ +++++++l ++l + ++ +l FUN_001463-T1 1239 VLLDCTAETsGVKTLRQRILQLITKCKCKghsligprvPQNFLSLLNIIRRQAQRLEL-PILTLANVRRL 1307 478999999999***********98777799999999999999999999999999999.88888777776 PP >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.46 3.5e+02 2 16 .. 714 728 .. 713 729 .. 0.89 2 ? 4.7 0.3 0.072 54 4 17 .. 746 759 .. 745 759 .. 0.90 3 ? 2.8 0.0 0.28 2.1e+02 3 14 .. 769 780 .. 767 781 .. 0.88 4 ? 4.1 0.9 0.11 86 2 16 .. 791 805 .. 790 805 .. 0.91 5 ! 8.5 0.1 0.0044 3.3 4 16 .. 820 832 .. 818 834 .. 0.90 6 ? 1.7 0.0 0.64 4.8e+02 5 15 .. 845 855 .. 843 857 .. 0.92 7 ? 3.3 0.8 0.2 1.5e+02 5 15 .. 868 878 .. 864 879 .. 0.89 8 ? 0.6 0.1 1.4 1.1e+03 2 16 .. 913 927 .. 912 933 .. 0.85 9 ? 1.8 0.0 0.59 4.4e+02 3 15 .. 945 957 .. 943 958 .. 0.87 10 ? -0.5 0.1 3.4 2.5e+03 5 15 .. 995 1005 .. 993 1006 .. 0.90 11 ? 3.6 0.0 0.16 1.2e+02 3 15 .. 1016 1029 .. 1014 1030 .. 0.85 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.46 LRR_6 2 nttLteLdLsgNdIg 16 n t++ dLs N+I FUN_001463-T1 714 NATVRLIDLSRNNIE 728 889999*******96 PP == domain 2 score: 4.7 bits; conditional E-value: 0.072 LRR_6 4 tLteLdLsgNdIgD 17 ++++LdL++N+++D FUN_001463-T1 746 KVEKLDLNHNHLSD 759 6799********98 PP == domain 3 score: 2.8 bits; conditional E-value: 0.28 LRR_6 3 ttLteLdLsgNd 14 ++L++++Ls+N+ FUN_001463-T1 769 PKLQCVNLSHNE 780 79*********7 PP == domain 4 score: 4.1 bits; conditional E-value: 0.11 LRR_6 2 nttLteLdLsgNdIg 16 +t+++ L+Ls+N+I+ FUN_001463-T1 791 CTSVRLLNLSNNKIS 805 99***********95 PP == domain 5 score: 8.5 bits; conditional E-value: 0.0044 LRR_6 4 tLteLdLsgNdIg 16 +L++L+Ls+N+I+ FUN_001463-T1 820 MLESLNLSHNEIS 832 69**********7 PP == domain 6 score: 1.7 bits; conditional E-value: 0.64 LRR_6 5 LteLdLsgNdI 15 Lt+L L+gNdI FUN_001463-T1 845 LTSLYLAGNDI 855 9*********7 PP == domain 7 score: 3.3 bits; conditional E-value: 0.2 LRR_6 5 LteLdLsgNdI 15 L++LdLs+N++ FUN_001463-T1 868 LRTLDLSNNHL 878 9********97 PP == domain 8 score: 0.6 bits; conditional E-value: 1.4 LRR_6 2 nttLteLdLsgNdIg 16 t+L++ L+ N++g FUN_001463-T1 913 LTNLKTIRLNKNKLG 927 599**********99 PP == domain 9 score: 1.8 bits; conditional E-value: 0.59 LRR_6 3 ttLteLdLsgNdI 15 ++++++dLs+N++ FUN_001463-T1 945 PNVKVVDLSSNGL 957 799********97 PP == domain 10 score: -0.5 bits; conditional E-value: 3.4 LRR_6 5 LteLdLsgNdI 15 L+ L Ls+N++ FUN_001463-T1 995 LERLALSDNNL 1005 899******97 PP == domain 11 score: 3.6 bits; conditional E-value: 0.16 LRR_6 3 ttLteLdLsgNd.I 15 t+L +LdLs N I FUN_001463-T1 1016 TSLMSLDLSRNPgI 1029 89*********866 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 2.3 1.8e+03 102 156 .. 44 100 .. 30 107 .. 0.79 2 ? 12.9 0.0 0.00014 0.1 3 27 .. 1085 1109 .. 1084 1116 .. 0.88 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 2.3 NACHT 102 ekqpvrtlLssllrkkllpeasllltvrpdalrklregleea..avlevegfseedr 156 ++ + l+ +l + l++ a+ l++ ++ ++ lre+l ++ +v ++++++ ++ FUN_001463-T1 44 HRCVMAALMLHLDDQDLCQAACQTLASMTNSSSSLRESLMSKglHVHIIQAMKQHRK 100 566777888899999999999999999999999999999999866666777777665 PP == domain 2 score: 12.9 bits; conditional E-value: 0.00014 NACHT 3 vilqGeaGsGKTtLlqklalawaeg 27 +++ G+aG GKTtLl ++ + a+g FUN_001463-T1 1085 LVVVGKAGRGKTTLLNQIQEENATG 1109 589***************9988776 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 3.9e-05 0.029 21 54 .. 1085 1119 .. 1061 1176 .. 0.68 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 3.9e-05 NB-ARC 21 valvGmgGvGKttLakeifnklsevegrFdvva..w 54 + +vG++G GKttL+++i ++ + ++ ++d+++ w FUN_001463-T1 1085 LVVVGKAGRGKTTLLNQIQEE-NATGPHHDIMVreW 1119 679******************.88888999665224 PP >> LRR_5 BspA type Leucine rich repeat region (6 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.6 0.34 2.5e+02 34 96 .. 745 809 .. 714 826 .. 0.71 2 ? 11.1 0.0 0.00052 0.39 32 89 .. 864 924 .. 845 931 .. 0.76 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.34 LRR_5 34 tslksitlpss.ltsigsyaFsnc.slesitipssltsigeyaFsncsnlksitlpenltsigss 96 +++++++l+++ l+ + ++ + + +l+ ++++ + + ++F c++++ ++l++n sigss FUN_001463-T1 745 SKVEKLDLNHNhLSDFPDELSEAMpKLQCVNLSHNEFCVLPFSFITCTSVRLLNLSNNKISIGSS 809 45566666554466666666667777777777777777777788888888888888887777765 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00052 LRR_5 32 nctslksitlpss.ltsigsyaFsnc.slesitips.sltsigeyaFsncsnlksitlpen 89 n ++l++++l+++ l++i + s+c sl ++ ++ lts++e++ ++ +nlk+i l++n FUN_001463-T1 864 NLRQLRTLDLSNNhLKEIPPEFLSEClSLDTLVASNnGLTSLPESIAASLTNLKTIRLNKN 924 5567788888775588888888888888888888764688888888888888888888665 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00035 0.27 12 62 .. 1070 1131 .. 1064 1155 .. 0.69 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00035 AAA_16 12 LlallervrsgrpplvlvsGeaGvGKSalvrellralera.........alv..lsgkcdel 62 L++ l++ +++v+G aG GK++l+++++++ ++ ++v + + c+ + FUN_001463-T1 1070 LHSRLKNSVPYYRMNLVVVGKAGRGKTTLLNQIQEENATGphhdimvreWHVkdTKAECKTC 1131 6666664444445899******************8665555666665555556666666666 PP >> nSTAND_NTPase5 Novel STAND NTPase 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00023 0.17 43 77 .. 1084 1118 .. 1058 1145 .. 0.71 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00023 nSTAND_NTPase5 43 vvlvlGpaGeGKttaLmqvavelaaakgwtvlwrd 77 +v G+aG GKtt+L q+ e a+ ++ ++ r+ FUN_001463-T1 1084 NLVVVGKAGRGKTTLLNQIQEENATGPHHDIMVRE 1118 3899**************98887766665555555 PP >> WHD_HELB DNA helicase B winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 2.2 1.7e+03 6 38 .. 329 361 .. 326 367 .. 0.88 2 ? 8.5 0.0 0.0045 3.4 67 104 .. 1300 1337 .. 1292 1342 .. 0.90 3 ? -1.1 0.0 4.3 3.2e+03 85 102 .. 1730 1747 .. 1714 1751 .. 0.78 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 2.2 WHD_HELB 6 keepwkLGFskilykelklircEakleafeqcg 38 +e w L+F + l++ + l+ c + l ++ +c FUN_001463-T1 329 SECIWYLAFDRELKQSMLLSACAVGLLKLADCL 361 6789******************99999999995 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0045 WHD_HELB 67 TyveekeLtkklskkmsveeawealkfLkeqkvvveek 104 T + ++L+++ + +m+ +e+++a+kf++e +vvv FUN_001463-T1 1300 TLANVRRLMQENELRMDDTEMEQAIKFMSEAGVVVHRD 1337 66778899999999********************9865 PP == domain 3 score: -1.1 bits; conditional E-value: 4.3 WHD_HELB 85 eeawealkfLkeqkvvve 102 ++ e l fL+++ +v + FUN_001463-T1 1730 LQVAEGLAFLHDNMIVYR 1747 578899*********976 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.00025 0.19 4 37 .. 1082 1115 .. 1080 1160 .. 0.66 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00025 Septin 4 eftlmvvGesglGkstlinslfetdlieerkiee 37 ++l+vvG+ g Gk+tl+n + e++ + ++ FUN_001463-T1 1082 RMNLVVVGKAGRGKTTLLNQIQEENATGPHHDIM 1115 589*****************99988776543333 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.094 70 33 118 .. 1940 2024 .. 1934 2038 .. 0.74 2 ? -1.5 0.0 2.3 1.8e+03 95 165 .. 2059 2131 .. 2029 2146 .. 0.64 3 ? 5.5 0.0 0.016 12 57 101 .. 2160 2204 .. 2123 2221 .. 0.83 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.094 WD40_CDC20-Fz 33 lwnaetgevkelldlseesdyvtsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalawnenllssGsrdgkilhh 118 +++ ++ v+ ++ + ++ v s+ + ++++ Gt sg++ ++d+ ++k+ + + + v +l+ e+ +++G +g++ ++ FUN_001463-T1 1940 IIDLCDKGVEGCTGTYIRDRRVKSILAVD-SDTVLAGTLSGTIWVFDAVNHKCEFSQPQLPNGVLCLKQYEDKVVAGLANGQLAVY 2024 55555555555555555666677776655.567778999********999998777777788999999999999999999988765 PP == domain 2 score: -1.5 bits; conditional E-value: 2.3 WD40_CDC20-Fz 95 rvgalawnenllssGsrdgkilhhDvrtkelevvktlkahk.qe..vcglkwspdgrllAsGgndntvkiwdlr 165 v+++a ++ +++G+ ++ ++ + + ele+++++++++ +e v ++++ ++ l +s +++k+w++ FUN_001463-T1 2059 PVACIAIGKKRIFCGCGNEVVVLQVNESGELEIENRWNGEEkSEsvVLNIAVASN-LLWTSTRGSSVIKCWEHC 2131 5778888888888888877777776667777777777654312211333333333.344444555555666554 PP == domain 3 score: 5.5 bits; conditional E-value: 0.016 WD40_CDC20-Fz 57 vkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalaw 101 v+ ++++L +G sg++ l+d +++k ++ +++h + v +l FUN_001463-T1 2160 VSLLLANRTLWIGLGSGHMILVDSSSRKLVSIIRRHMAAVRCLVD 2204 4555567899******************************99865 PP >> DUF7334 Family of unknown function (DUF7334) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.00058 0.44 9 38 .. 166 195 .. 160 199 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00058 DUF7334 9 vWqlakieelDdFiakvakaFPDalevvhv 38 vW ie++ d i kv ++PD +++ v FUN_001463-T1 166 VWHQSAIEGVHDMILKVMETYPDEVDLAEV 195 9**********************9987665 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00059 0.44 108 130 .. 1084 1106 .. 1049 1132 .. 0.76 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00059 RsgA_GTPase 108 ttvllGqSGvGKStLinallpel 130 v++G+ G GK+tL+n++++e+ FUN_001463-T1 1084 NLVVVGKAGRGKTTLLNQIQEEN 1106 3699***************9974 PP >> CSD_RNase_II CSD-like barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.47 3.5e+02 1 23 [. 681 704 .. 681 709 .. 0.93 2 ? 7.4 0.0 0.0075 5.6 27 56 .. 1117 1146 .. 1116 1149 .. 0.90 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.47 CSD_RNase_II 1 lekGtLiEFkkdgerr.LaVverp 23 lekG L++ ++++r L++ +r+ FUN_001463-T1 681 LEKGNLLSVSRRSSRGdLGLRQRR 704 79*************99**99986 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0075 CSD_RNase_II 27 knwiviDqngqshsvhprqityeVpgesfk 56 ++w v D +++ + h r+++y+++ +fk FUN_001463-T1 1117 REWHVKDTKAECKTCHRRSVNYAITTWDFK 1146 68**********************988777 PP >> LRR_13 Disease resistance protein RPS4B-like, leucine-rich repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 2.4 1.8e+03 128 179 .. 767 798 .. 723 812 .. 0.57 2 ? 6.7 0.2 0.0099 7.4 8 163 .. 871 1026 .. 864 1043 .. 0.58 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2.4 LRR_13 128 cfpkleeliasennfvslpecikecdhltsldvslcgelqkipkctklriln 179 ++pkl+ + s n+f lp c +r+ln FUN_001463-T1 767 AMPKLQCVNLSHNEFCVLPFSFITCT--------------------SVRLLN 798 34555555555555555555555554....................444444 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0099 LRR_13 8 ldlnlcvrlehfpeimkemnkplkiymintaikelpesig.nltglvcieip.......ssrklkylpsslfmlpnvvafkiggcsqlresfrg 93 ldl e pe + e + n + lpesi lt l i + s++k +p l+ lpnv + + g FUN_001463-T1 871 LDLSNNHLKEIPPEFLSECLSLDTLVASNNGLTSLPESIAaSLTNLKTIRLNknklgerSAKKPFPIPRFLLTLPNVKVVDLS--------SNG 956 55554444455556666655555556666677777777742467777776651111111223333355555555555444432........233 PP LRR_13 94 fvqs.psaanvrptlrtlyfgngglsdedllailycfpkleeliasennfvslpecikecdhltsldvslc 163 + + p + ++ l++ + + l + +le l s+nn+ +p i e l sld+s FUN_001463-T1 957 LEEIpPPISWATQQMKELFLADNKIKKLSLEG-AKKWCQLERLALSDNNLKQVPSGIGELTSLMSLDLSRN 1026 33320334445556677777776666655543.33456899999999999999999999999999998865 PP >> LRR_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, LRR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.3 0.058 43 26 95 .. 750 823 .. 737 834 .. 0.78 2 ? 2.7 0.4 0.17 1.3e+02 39 61 .. 863 885 .. 843 903 .. 0.69 3 ? 7.4 1.0 0.0062 4.7 23 86 .. 868 936 .. 862 942 .. 0.79 4 ? 0.8 0.1 0.63 4.8e+02 36 100 .. 939 1007 .. 937 1025 .. 0.74 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.058 LRR_LRWD1 26 lellsehld..p.nllgrlkklkeldlsnnlletlpan.lglshlrilrctnnqlgdvttlhqfpeleelsleg 95 l+l +hl p +l + kl+ ++ls n + lp + + +r+l +nn++ ++ h pe + le FUN_001463-T1 750 LDLNHNHLSdfPdELSEAMPKLQCVNLSHNEFCVLPFSfITCTSVRLLNLSNNKISIGSSQHPNPEKRAIMLES 823 44444554322315667789****************76267899***********9999999999988887775 PP == domain 2 score: 2.7 bits; conditional E-value: 0.17 LRR_LRWD1 39 grlkklkeldlsnnlletlpanl 61 l++l+ ldlsnn l+ +p ++ FUN_001463-T1 863 LNLRQLRTLDLSNNHLKEIPPEF 885 4689999*******999998765 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0062 LRR_LRWD1 23 lsglellsehld...pnllgrlkklkeldlsnnlletlpanlg..lshlrilrctnnqlgdvttlhqfp 86 l l+l +hl p++l l l snn l +lp + l+ l+ +r +n+lg+ ++ + fp FUN_001463-T1 868 LRTLDLSNNHLKeipPEFLSECLSLDTLVASNNGLTSLPESIAasLTNLKTIRLNKNKLGERSAKKPFP 936 44556666665433399999999****************9875227899***********998888887 PP == domain 4 score: 0.8 bits; conditional E-value: 0.63 LRR_LRWD1 36 nllgrlkklkeldlsnnlletlpanlgl..shlrilrctnnqlgdvt..tlhqfpeleelslegnpflt 100 +l l ++k +dls n le +p + +++ l ++n++ ++ +++ +le l+l n + FUN_001463-T1 939 RFLLTLPNVKVVDLSSNGLEEIPPPISWatQQMKELFLADNKIKKLSleGAKKWCQLERLALSDNNLKQ 1007 566678889999999999999987665411567778888888876542156788888888888887655 PP >> LRR_EndoS Endo-beta-N-acetylglucosaminidase EndoS LRR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 3.1 2.3e+03 68 93 .. 93 121 .. 65 128 .. 0.77 2 ? 2.5 0.2 0.31 2.3e+02 74 116 .] 737 779 .. 703 779 .. 0.79 3 ? 3.2 0.0 0.19 1.4e+02 82 116 .] 843 876 .. 838 876 .. 0.91 4 ? 1.5 0.2 0.64 4.8e+02 78 116 .] 886 924 .. 878 924 .. 0.92 5 ? 4.6 0.4 0.066 50 46 116 .] 980 1026 .. 967 1060 .. 0.58 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 3.1 LRR_EndoS 68 eslkkek...elelkgltaLktldlsglk 93 +++k+++ +++ g+ aL+ l lsg FUN_001463-T1 93 QAMKQHRkdaGVQIWGCRALRGLSLSGYA 121 455555466699*************9975 PP == domain 2 score: 2.5 bits; conditional E-value: 0.31 LRR_EndoS 74 kelelkgltaLktldlsglkleklealdveslksLkkvDiSeN 116 + l+ ++ +++ldl+ +l ++ + +e +++L+ v +S+N FUN_001463-T1 737 SQAFLAYFSKVEKLDLNHNHLSDFPDELSEAMPKLQCVNLSHN 779 366678888999**************999************98 PP == domain 3 score: 3.2 bits; conditional E-value: 0.19 LRR_EndoS 82 taLktldlsglkleklealdveslksLkkvDiSeN 116 +aL+ l l+g ++ +l a+ +l++L+++D+S+N FUN_001463-T1 843 PALTSLYLAGNDIINLPAF-PLNLRQLRTLDLSNN 876 7999************995.679***********9 PP == domain 4 score: 1.5 bits; conditional E-value: 0.64 LRR_EndoS 78 lkgltaLktldlsglkleklealdveslksLkkvDiSeN 116 l+++ +L+tl s+ +l +l + ++sl++Lk++ + +N FUN_001463-T1 886 LSECLSLDTLVASNNGLTSLPESIAASLTNLKTIRLNKN 924 78999*****************99*********988776 PP == domain 5 score: 4.6 bits; conditional E-value: 0.066 LRR_EndoS 46 klkkltlkgltklkelsesslpeslkkekelelkgltaLktldlsglkleklealdveslksLkkvDiSeN 116 k+kkl+l+g +k +l++ l ++ k+ + +lt+L ldls N FUN_001463-T1 980 KIKKLSLEGAKKWCQLERLALSDNNLKQVPSGIGELTSLMSLDLS------------------------RN 1026 455566666666666666555543222334445555555555553........................33 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2269 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 793 (0.0310433); expected 510.9 (0.02) Passed bias filter: 697 (0.0272852); expected 510.9 (0.02) Passed Vit filter: 121 (0.00473674); expected 25.5 (0.001) Passed Fwd filter: 35 (0.00137013); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 34 [number of targets reported over threshold] # CPU time: 0.75u 0.38s 00:00:01.12 Elapsed: 00:00:00.45 # Mc/sec: 20296.10 // Query: FUN_001464-T1 [L=312] Description: FUN_001464 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-91 307.3 19.9 1.1e-90 304.0 19.9 1.9 1 Rtf2 Rtf2 RING-finger 0.0074 16.4 0.2 0.017 15.2 0.2 1.6 1 zf_C2H2_13 Zinc finger domain 0.0097 16.5 0.1 0.02 15.4 0.1 1.5 1 zf-NOSIP Zinc-finger of nitric oxide synthase-interacting ------ inclusion threshold ------ 3.9 8.1 14.8 6.1 7.4 14.8 1.2 1 Ashwin Developmental protein Domain annotation for each model (and alignments): >> Rtf2 Rtf2 RING-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 304.0 19.9 1.7e-94 1.1e-90 1 257 [. 1 295 [. 1 296 [. 0.94 Alignments for each domain: == domain 1 score: 304.0 bits; conditional E-value: 1.7e-94 Rtf2 1 mGnDGGtipkRdelvkekkkeekvdkeeerkarwklCaLsqepLkkPivacrlGkLYnkdavieaLldkskslskaashikglkdvvelkltenpa 96 mG+DGGtipkRdelv++kkk+e+vdk++e +a+w++CaLsq +L+ Piv+c+lG+LYnk+av+e+L+dks+ +++ ashi++lkdv+el+lt+npa FUN_001464-T1 1 MGCDGGTIPKRDELVRMKKKPEQVDKNYELNAKWFHCALSQAELRTPIVCCELGNLYNKEAVLEYLIDKSSVTTDIASHIRSLKDVKELNLTSNPA 96 9*********************************************************************************************** PP Rtf2 97 feeskk.....tkdskeapfiCpltglemngkykFvalrkCGcVfsekalkevkskvClvCgkeykeedvvvlnpteeelellkarleeekakkkk 187 fe++ + d + +pfiCp++g+emng+ykF++l+kCGcVfsekalkev + vC +Cgk+++++d++v+n++e+e+ ++k+++ee+++k+k FUN_001464-T1 97 FEQKAMehadsYLDFQASPFICPVVGIEMNGRYKFCFLWKCGCVFSEKALKEVPTTVCNTCGKPLSNDDIIVINGSEDEVRAMKVKMEERRQKSKL 192 **9998999999************************************************************************************ PP Rtf2 188 kkkakkkkkakekgskaekeakskksseak..................................lsskkgkkkekkklkkkrslakkkeksevyks 249 +kkakk+k +++++s +++++ +++ +++k s ++++k + +l+k++++a+++++s+v+ks FUN_001464-T1 193 EKKAKKTKISETSTSINSSTSFNSS-EISKdgpekpakraktehaassskasasdvkvtaakltASGTSSSKGKIPELSKHKTVAEDPKASKVFKS 287 *******999877776665554444.4444589*****************************9877777888888899999*************** PP Rtf2 250 lftsskke 257 lf ss+k+ FUN_001464-T1 288 LFSSSHKD 295 **999875 PP >> zf_C2H2_13 Zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.2 2.7e-06 0.017 19 33 .. 153 167 .. 150 168 .. 0.91 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.7e-06 zf_C2H2_13 19 vCnkCGkPisleaiv 33 vCn CGkP+s + i+ FUN_001464-T1 153 VCNTCGKPLSNDDII 167 9*********98886 PP >> zf-NOSIP Zinc-finger of nitric oxide synthase-interacting protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.1 3.2e-06 0.02 42 73 .. 36 68 .. 28 70 .. 0.85 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 3.2e-06 zf-NOSIP 42 ccslslqpcrdpvl.tedgylyekeailqyilh 73 c+ls r p++ e g ly+kea+l+y++ FUN_001464-T1 36 HCALSQAELRTPIVcCELGNLYNKEAVLEYLID 68 489*********762699************975 PP >> Ashwin Developmental protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 14.8 0.00095 6.1 89 206 .. 166 286 .. 143 300 .. 0.75 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.00095 Ashwin 89 livfdGsStsT.sikvkktengsadrLkpppssksvknaiRklsnsssnssssalssslatdlkvesanetkqnnsvaiskstvasvksppl..st 181 iv +Gs + +kvk e ++ +L + + ++++++ ++ +s+s +ss++++ + ++ k +++++ + ++++ s +v+ k + + s+ FUN_001464-T1 166 IIVINGSEDEVrAMKVKMEERRQKSKLEKKAKKTKISETSTSINSSTSFNSSEISKDGPEKPAKRAKTEHAASSSKASASDVKVTAAKLTASgtSS 261 49999999776589**************99999999999999988888888888888888888888777777777666665555555543331155 PP Ashwin 182 vagtsvvklKrvapkeesdsvndlk 206 ++g++ +K+ ++ e+ ++++ +k FUN_001464-T1 262 SKGKIPELSKHKTVAEDPKASKVFK 286 5666777778888888877776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (312 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2587 (0.101272); expected 510.9 (0.02) Passed bias filter: 952 (0.0372676); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3158.25 // Query: FUN_001465-T1 [L=389] Description: FUN_001465 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-38 130.6 0.0 1.2e-37 129.7 0.0 1.5 1 CTLH CTLH/CRA C-terminal to LisH motif domain 1.2e-06 28.9 1.8 3.8e-06 27.3 1.8 1.9 1 zf-RING_UBOX RING-type zinc-finger 0.00015 21.7 0.0 0.00027 20.9 0.0 1.4 1 Rtf2 Rtf2 RING-finger 0.0025 18.5 2.0 0.0066 17.2 2.0 1.8 1 zf-RING_2 Ring finger domain ------ inclusion threshold ------ 0.019 15.4 1.7 0.048 14.1 1.7 1.7 1 zf-RING_5 zinc-RING finger domain 0.025 15.2 0.1 0.23 12.1 0.0 2.3 3 STATB_N Signal transducer and activator of transcript 0.11 12.8 2.4 0.28 11.5 2.4 1.7 1 zf-Nse Zinc-finger of the MIZ type in Nse subunit 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 Noc2 Noc2p family 0.24 11.8 0.4 24 5.3 0.0 2.4 2 DUF655 Protein of unknown function (DUF655) 0.5 10.8 2.7 1.3 9.4 2.7 1.8 1 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) Domain annotation for each model (and alignments): >> CTLH CTLH/CRA C-terminal to LisH motif domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.7 0.0 4.9e-41 1.2e-37 2 145 .. 153 293 .. 152 294 .. 0.97 Alignments for each domain: == domain 1 score: 129.7 bits; conditional E-value: 4.9e-41 CTLH 2 fkernkIlesilngdleealewcnenkpellksnsnLeFeLrllqfieliregkileAleyarenlapfkeehlkeleklmglLafedpesktlss 97 f+e+n+Ile+ ++++l++al+w++ + el+ ++s+LeF L++l+f+ l++e+ ++Al y+r++ +++++ h k++++lm++L++++ ++s FUN_001465-T1 153 FTELNRILEACRERNLDPALQWAQARHDELRLRGSSLEFRLHKLKFLDLLKERRHKDALVYSRNFAQFASD-HTKDVQQLMACLLYSQT--GLENS 245 89**************************************************************7788888.**************995..67*** PP CTLH 98 pyksllsssrweklasefnrailkllglssespLeillkaglsalktl 145 py+sll++ +w ++++ f r+ + llgls espL+++++ag++al++l FUN_001465-T1 246 PYASLLDPIHWVDICDVFARDACGLLGLSLESPLQVCVTAGCIALPSL 293 *********************************************987 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 1.8 1.5e-09 3.8e-06 1 39 [] 333 372 .. 333 372 .. 0.93 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 1.5e-09 zf-RING_UBOX 1 CpICleeft..dP.lvlpCGHtfCreClwelskkekgkikCP 39 CpI +e+ + +P ++l+CGH++ ++ l ++ +++k+kCP FUN_001465-T1 333 CPILREQCSdtNPpVRLSCGHVISKDAL--TKLTHGNKVKCP 372 *********9*5557799**********..9**********9 PP >> Rtf2 Rtf2 RING-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 1e-07 0.00027 108 164 .. 328 386 .. 297 388 .. 0.87 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1e-07 Rtf2 108 eapfiCpltglemngkykFvalrkCGcVfsekalkevk...skvClvCgkeykeedvvvl 164 ++ f Cp+ + + ++++ v l +CG+V+s+ al ++ + +C+ C e + +d + FUN_001465-T1 328 HSLFACPILREQCSDTNPPVRL-SCGHVISKDALTKLThgnKVKCPYCPLEMTPNDAREI 386 678**************99887.7*************8777778****999998887555 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 2.0 2.6e-06 0.0066 3 43 .. 333 374 .. 331 375 .. 0.87 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 2.6e-06 zf-RING_2 3 CpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst.CPlC 43 Cpi e++++++ +++l CgHv+ k+ l k+++ ++ CP+C FUN_001465-T1 333 CPILREQCSDTNPPVRLSCGHVISKDALTKLTHGNKVkCPYC 374 9999999***********************55555559**** PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 1.7 1.9e-05 0.048 2 41 .. 333 374 .. 332 375 .. 0.91 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.9e-05 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll..eerqCpiC 41 C++ ++++s+t +++ +sCgH++ ++ l+kl+ ++ +Cp C FUN_001465-T1 333 CPILREQCSDTNPPVRLSCGHVISKDALTKLThgNKVKCPYC 374 666677889999*****************************9 PP >> STATB_N Signal transducer and activator of transcription b N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.87 2.2e+03 88 118 .. 10 40 .. 4 52 .. 0.70 2 ? -1.5 0.0 1.4 3.7e+03 35 71 .. 30 66 .. 18 83 .. 0.61 3 ? 12.1 0.0 9.1e-05 0.23 51 99 .. 108 156 .. 89 165 .. 0.83 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.87 STATB_N 88 eldtidtqfeyfGelleqtlsGleylkeeyp 118 el+ + ++++ +Ge + l+ l y + +++ FUN_001465-T1 10 ELERLAKKYNNLGEHTDSSLTELIYQIVTIQ 40 6777777888888888877777777655444 PP == domain 2 score: -1.5 bits; conditional E-value: 1.4 STATB_N 35 sallsrilktleellaaledekqyllgdvllsWavkq 71 ++l+ +i+++ e+ll+a +d l+ ll+ + ++ FUN_001465-T1 30 TELIYQIVTIQEDLLKASKDGEVPPLQLHLLNQSCRK 66 5677777777777777776655444444444444444 PP == domain 3 score: 12.1 bits; conditional E-value: 9.1e-05 STATB_N 51 aledekqyllgdvllsWavkqqkvsigtlwtqqlhykeldtidtqfeyf 99 +++ e + ll++v+++ ++q ++ i+ + t++++ + d+ ++ f + FUN_001465-T1 108 VFDGENATLLNEVICEHLLRQGRLEISEQMTKEANLQLNDSRKEPFTEL 156 7999****************************99988777666666554 PP >> zf-Nse Zinc-finger of the MIZ type in Nse subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 2.4 0.00011 0.28 13 56 .. 332 374 .. 327 375 .. 0.83 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00011 zf-Nse 13 kcPltlqpf..kePvtskkCnHvfekeaIlellkrkkkvkCPvvgC 56 cP+ +++ ++P C+Hv k+a+++l + +kvkCP C FUN_001465-T1 332 ACPILREQCsdTNPPVRLSCGHVISKDALTKLT-HGNKVKCPY--C 374 5888777762246888899************98.99******8..6 PP >> Noc2 Noc2p family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00014 0.37 93 136 .. 14 61 .. 4 72 .. 0.85 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00014 Noc2 93 lsaackk....keselkpLiyplvqvilgvirliptaryfPLrlhlir 136 l++++++ ++s l +Liy++v + ++++ + + PL+lhl++ FUN_001465-T1 14 LAKKYNNlgehTDSSLTELIYQIVTIQEDLLKASKDGEVPPLQLHLLN 61 5555665677789********************************985 PP >> DUF655 Protein of unknown function (DUF655) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.0095 24 73 100 .. 16 43 .. 2 94 .. 0.81 2 ? 4.5 0.1 0.016 42 109 150 .. 187 231 .. 177 240 .. 0.78 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0095 DUF655 73 ikyedLtdvarseLpyvveeivkekEkr 100 ky++L + + s L +++++iv+ +E+ FUN_001465-T1 16 KKYNNLGEHTDSSLTELIYQIVTIQEDL 43 48************************96 PP == domain 2 score: 4.5 bits; conditional E-value: 0.016 DUF655 109 epitlRlHqLelLpgigkk.llrkileeRkkkpFes..Fediker 150 ++ RlH+L+ L ++++ + ++++ R+ +F s +d+++ FUN_001465-T1 187 SSLEFRLHKLKFLDLLKERrHKDALVYSRNFAQFASdhTKDVQQL 231 57899*********9997626677889999999988334566655 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 2.7 0.00051 1.3 9 40 .] 344 374 .. 333 374 .. 0.83 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00051 zf-C3HC4 9 kepvtllpCgHsfCssCiksllesnnvkCplC 40 +pv l CgH ++ +++l+ n+vkCp C FUN_001465-T1 344 NPPV-RLSCGHVISKDALTKLTHGNKVKCPYC 374 3445.89************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (389 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1151 (0.0450577); expected 510.9 (0.02) Passed bias filter: 885 (0.0346447); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.30u 0.43s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3760.10 // Query: FUN_001466-T1 [L=427] Description: FUN_001466 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-31 108.7 0.4 9.7e-31 107.9 0.4 1.4 1 Trypsin_2 Trypsin-like peptidase domain 2.7e-17 63.8 0.1 8.3e-17 62.2 0.0 1.8 2 Trypsin Trypsin 6.9e-11 42.8 0.0 1.4e-10 41.7 0.0 1.6 1 PDZ_2 PDZ domain 2.3e-10 40.5 0.1 4.7e-10 39.5 0.1 1.6 1 PDZ_6 PDZ domain 2.3e-08 34.7 0.1 6e-08 33.4 0.1 1.6 1 PDZ PDZ domain 0.0016 18.2 1.6 0.47 10.1 0.3 2.2 2 Peptidase_S32 Equine arteritis virus serine endopeptidase S3 0.0023 17.2 1.0 1.3 8.1 0.5 2.2 2 Peptidase_S46 Peptidase S46 0.0073 16.5 0.1 0.021 15.0 0.0 1.8 2 AIM3_BBC1_C AIM3/BBC1 Cysteine proteinase-fold domain ------ inclusion threshold ------ 0.049 14.1 0.0 0.28 11.7 0.0 2.2 2 PDZ_Tricorn Tricorn protease PDZ domain 0.16 12.1 0.1 0.44 10.8 0.1 1.7 1 LSM LSM domain 0.18 12.5 0.0 0.44 11.3 0.0 1.7 1 SM-ATX Ataxin 2 SM domain 0.22 12.1 0.1 3.3 8.3 0.0 2.7 3 HAS-barrel HAS barrel domain Domain annotation for each model (and alignments): >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.9 0.4 4.6e-34 9.7e-31 1 145 [] 137 278 .. 137 278 .. 0.97 Alignments for each domain: == domain 1 score: 107.9 bits; conditional E-value: 4.6e-34 Trypsin_2 1 GsGfvvssdglvlTnaHvvadaeeaavvaekvsvaladgreyaatvvaadpelDlallkv..sedgaglpplplgdsaplvggervyavGyplgge 94 GsGf+v +dg+vlTnaH+v++a ++ v l+dgr++++ vv d e Dla +k+ ++ ++p+l+lg+s+++++ge+v+a+G pl FUN_001466-T1 137 GSGFIVTEDGMVLTNAHLVENAMKVSV-------KLKDGRQFSGIVVDIDLENDLATVKLdlNNKTVKFPTLTLGSSSSIRPGEWVVAMGSPLQLS 225 9**************************.......*********************************************************99999 PP Trypsin_2 95 kleslseGtvsavse....srderddeellqtdaslspGsSGgPlfdaeGrvvGi 145 + ++++G+vs v++ +++ e++qtda+++ G+SGgPl++ +G v+Gi FUN_001466-T1 226 N--TITAGIVSTVHRageeIGLPNRGLEYIQTDAAINIGNSGGPLVNLDGDVIGI 278 9..9************99888888999999************************8 PP >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 1.9 4.1e+03 6 22 .. 41 57 .. 38 61 .. 0.81 2 ! 62.2 0.0 3.9e-20 8.3e-17 22 219 .. 132 301 .. 105 302 .. 0.76 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 1.9 Trypsin 6 eaqagsfpwqvslqlss 22 ++q+ +pw++s++l++ FUN_001466-T1 41 STQRLPWPWMGSVALGG 57 677889******99865 PP == domain 2 score: 62.2 bits; conditional E-value: 3.9e-20 Trypsin 22 sgkhfCGGslisen.wvlTAaHCvsnassvkvvlgehnisksegseqklkvekvivhpnynsdtldnDiallklkspvtlgdavrpiclpaasssl 116 + + + +G++++e+ vlT+aH v+n ++kv +++ ++g +++ ++v + +l+nD+a +kl+ + +++ + ++ l + ss FUN_001466-T1 132 GPTSAGSGFIVTEDgMVLTNAHLVEN--AMKV-----SVKLKDGR----QFSGIVV----DI-DLENDLATVKLDLN-NKTVKFPTLTLGS-SS-- 207 3355678******************9..8888.....46778883....4444434....33.3478**********.6777777777777.44.. PP Trypsin 117 avgttclvsGwGntkelglsdtlqevnvpvvsre.ecrsayggkvtdnmicagakggkdacqGDSGGPlvcsdgeliGivswgkgcasgnkpgvyt 211 + + + +v+++G++ +l +t++ + v++v r+ e ++++ ++i+++a +++ G+SGGPlv+ dg +iGi+ a g +++ + FUN_001466-T1 208 SIRPGEWVVAMGSPLQLS--NTITAGIVSTVHRAgEEIG-LPNR-GLEYIQTDA----AINIGNSGGPLVNLDGDVIGINAITMRFAAG--ISFSI 293 455558999999987777..99***********843333.5665.579******....**********************998777766..78888 PP Trypsin 212 rvssyadw 219 +++ ++d+ FUN_001466-T1 294 PIDAAKDF 301 88777765 PP >> PDZ_2 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.7 0.0 6.8e-14 1.4e-10 6 73 .. 352 416 .. 330 422 .. 0.86 Alignments for each domain: == domain 1 score: 41.7 bits; conditional E-value: 6.8e-14 PDZ_2 6 sfedledgvvVvnVksssPaakaglkagDvIlsidgkkvksltdleeallkkkpgdtvklqvlRdgkt 73 sf ++e gv V++++++sPa++agl+ gD+I++i+g+k +s+ ++++++ +g+t+++++ R++ t FUN_001466-T1 352 SFHKVEHGVLVAQINNGSPAQRAGLRSGDIITKINGNKTESSLQVHKVVQ---KGETLQMELVRGDHT 416 5667777****************************************995...689999999998876 PP >> PDZ_6 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.5 0.1 2.2e-13 4.7e-10 2 41 .. 362 401 .. 361 412 .. 0.82 Alignments for each domain: == domain 1 score: 39.5 bits; conditional E-value: 2.2e-13 PDZ_6 2 vtavvpgsPAerAGlrvGDiIlsvNGepvrsledvarllq 41 v++++ gsPA+rAGlr GDiI+++NG ++ s +v ++q FUN_001466-T1 362 VAQINNGSPAQRAGLRSGDIITKINGNKTESSLQVHKVVQ 401 789999***********************77777777777 PP >> PDZ PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.4 0.1 2.8e-11 6e-08 23 66 .. 352 400 .. 344 410 .. 0.79 Alignments for each domain: == domain 1 score: 33.4 bits; conditional E-value: 2.8e-11 PDZ 23 s....dkgifvsevlpggaaeaggLkaGDrIlsvNgqdvenl.sheeav 66 s ++g+ v++++ g++a+++gL+ GD+I+++Ng ++e+ ++ ++v FUN_001466-T1 352 SfhkvEHGVLVAQINNGSPAQRAGLRSGDIITKINGNKTESSlQVHKVV 400 4556789*****************************8887641444444 PP >> Peptidase_S32 Equine arteritis virus serine endopeptidase S32 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.3 0.00022 0.47 219 249 .. 124 154 .. 118 193 .. 0.74 2 ! 7.6 0.0 0.0013 2.7 137 225 .. 183 279 .. 174 289 .. 0.65 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00022 Peptidase_S32 219 gelvGvhtGsnkkGsglvttpsGktlgvaev 249 g + G htG + Gsg++ t++G +l+ a++ FUN_001466-T1 124 GFVFGTHTGPTSAGSGFIVTEDGMVLTNAHL 154 668899**************99999985543 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0013 Peptidase_S32 137 nkarvsivgfsqtltfktk..GDyalavvaelkGaa.Pklkla.qsttGraywltstgveegllgkevalcft....kcGDsGspvvdedgelvGv 224 + a+v+ + ++t++f t G ++ + e+ a+ +l+l+ t G + + +g e gl ++ ++ t + G+sG p+v+ dg+++G+ FUN_001466-T1 183 DLATVKLDLNNKTVKFPTLtlGSSSSIRPGEWVVAMgSPLQLSnTITAGIVSTVHRAGEEIGLPNRGLEYIQTdaaiNIGNSGGPLVNLDGDVIGI 278 5566666666666666543114444444455554442356777444557777778888888887777777776222256****************9 PP Peptidase_S32 225 h 225 FUN_001466-T1 279 N 279 6 PP >> Peptidase_S46 Peptidase S46 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.00099 2.1 48 71 .. 136 159 .. 133 167 .. 0.86 2 ! 8.1 0.5 0.0006 1.3 628 650 .. 257 279 .. 249 282 .. 0.87 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.00099 Peptidase_S46 48 gCsasfVSpdGLvlTNhhcayeai 71 +s+ +V +dG+vlTN+h + +a+ FUN_001466-T1 136 AGSGFIVTEDGMVLTNAHLVENAM 159 57999*************998876 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0006 Peptidase_S46 628 nDitGGNSGSpvlnakgelvGla 650 + i GNSG p++n +g+++G++ FUN_001466-T1 257 AAINIGNSGGPLVNLDGDVIGIN 279 56778****************98 PP >> AIM3_BBC1_C AIM3/BBC1 Cysteine proteinase-fold domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 3.4 7.2e+03 110 136 .. 161 187 .. 147 204 .. 0.58 2 ! 15.0 0.0 9.9e-06 0.021 45 96 .. 336 386 .. 332 416 .. 0.80 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 3.4 AIM3_BBC1_C 110 ysvevgkp.dhtavvvevdgkkkklrvv 136 +sv++++ + ++vv++d ++ l +v FUN_001466-T1 161 VSVKLKDGrQFSGIVVDIDLEN-DLATV 187 3333333325778999988764.34444 PP == domain 2 score: 15.0 bits; conditional E-value: 9.9e-06 AIM3_BBC1_C 45 wtLaseaLkavpqalapvgsrthGaliyankanasvkqddeirrGDIvelrn 96 tL ++L+++++ +++ + hG+l+ a+ +n s q + +r GDI++ n FUN_001466-T1 336 LTLTPQILNELRRRDQSFHKVEHGVLV-AQINNGSPAQRAGLRSGDIITKIN 386 5788999*******************7.677889999***********8655 PP >> PDZ_Tricorn Tricorn protease PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.6 3.4e+03 16 34 .. 306 324 .. 297 326 .. 0.89 2 ? 11.7 0.0 0.00013 0.28 28 74 .. 366 408 .. 348 418 .. 0.76 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.6 PDZ_Tricorn 16 vakilkGdssdeeerspLa 34 ++k+ +Gd+ + ++ pLa FUN_001466-T1 306 IEKVRNGDYRSRNTMRPLA 324 899******9999999986 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00013 PDZ_Tricorn 28 eerspLaepGvdvreGdlilavdgepvspeagiaelLvgkagqeveL 74 + sp ++ G++ Gd+i++++g++++++ +++++ +g++ ++ FUN_001466-T1 366 NNGSPAQRAGLR--SGDIITKINGNKTESSLQVHKVVQ--KGETLQM 408 567999999999..9***********998877776654..3334444 PP >> LSM LSM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.00021 0.44 10 29 .. 160 179 .. 157 181 .. 0.93 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00021 LSM 10 rvlvelkngrelrGtLkgfD 29 +v v+lk+gr+++G+++ +D FUN_001466-T1 160 KVSVKLKDGRQFSGIVVDID 179 79**************9998 PP >> SM-ATX Ataxin 2 SM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.0002 0.44 15 40 .. 160 185 .. 146 210 .. 0.90 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0002 SM-ATX 15 kvevtvknGevYeGifstaslekefg 40 kv+v++k+G +++Gi ++le+++ FUN_001466-T1 160 KVSVKLKDGRQFSGIVVDIDLENDLA 185 79******************988875 PP >> HAS-barrel HAS barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.41 8.7e+02 30 61 .. 162 189 .. 128 197 .. 0.76 2 ? 8.3 0.0 0.0016 3.3 9 49 .. 195 240 .. 191 262 .. 0.78 3 ? -2.5 0.0 3.7 7.9e+03 22 35 .. 399 413 .. 379 417 .. 0.69 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.41 HAS-barrel 30 eiegd.gervlGmvesirrgndelsndlalvls 61 +++ g+ + G+v +i +ndla v+ FUN_001466-T1 162 SVKLKdGRQFSGIVVDIDL-----ENDLATVKL 189 4555568999999999999.....777777765 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0016 HAS-barrel 9 ssnelifrvegskdvkvGeyVeiegd.....gervlGmvesirrgn 49 + ++++ ++ s++++ Ge+V++ g + ++ G+v+ ++r + FUN_001466-T1 195 TVKFPTLTLGSSSSIRPGEWVVAMGSplqlsNTITAGIVSTVHRAG 240 55677778888889*****************************943 PP == domain 3 score: -2.5 bits; conditional E-value: 3.7 HAS-barrel 22 dvkvGeyVeiegd.g 35 v+ Ge +++e++ g FUN_001466-T1 399 VVQKGETLQMELVrG 413 678888888887754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (427 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 813 (0.0318262); expected 510.9 (0.02) Passed bias filter: 761 (0.0297906); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4201.74 // Query: FUN_001467-T1 [L=456] Description: FUN_001467 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-52 179.6 0.2 1.9e-52 178.9 0.2 1.3 1 RAI16-like Retinoic acid induced 16-like protein 7.9e-29 100.1 2.4 2.3e-28 98.6 2.4 1.9 1 DUF5917 Family of unknown function (DUF5917) 3.4e-14 52.7 4.0 6.9e-14 51.7 4.0 1.5 1 KELAA KELAA motif Domain annotation for each model (and alignments): >> RAI16-like Retinoic acid induced 16-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 178.9 0.2 2.2e-56 1.9e-52 204 360 .] 39 196 .. 35 196 .. 0.98 Alignments for each domain: == domain 1 score: 178.9 bits; conditional E-value: 2.2e-56 RAI16-like 204 rldeklakedlasfpgkeaLdsFlsslefcnaliqeahsevaealldaikegFLvqvLepsLletseesilavtayLdlilrsitepaLlqeflsF 299 rld+++++ed+ sfpgk+ L+sFls+l+++++l++eah+ v +al+ ++e+FL++v+ep+L+++se +i+++ta+L++ ++ +t+p+Llqe+ F FUN_001467-T1 39 RLDHQSDDEDVLSFPGKRRLISFLSWLDYVDQLSKEAHKLVGKALAVGVRERFLQPVMEPALIQQSELGIITATAILRRCVKAVTSPHLLQEICIF 134 4699******************************************************************************************** PP RAI16-like 300 LLgeekspetse.ddghplldklierinsksdelsivtlrlfetllqlpeediLldLvLrnL 360 LLgee+spe + + +h+l+++li+r++++sde+si+tl+lfe+ll++p+e i ++LvLrnL FUN_001467-T1 135 LLGEETSPEVPSnTGDHKLRQTLIQRCDHLSDEVSIETLKLFEALLDKPCEIIFNNLVLRNL 196 ************9************************************************8 PP >> DUF5917 Family of unknown function (DUF5917) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.6 2.4 2.7e-32 2.3e-28 1 93 [. 320 412 .. 320 413 .. 0.99 Alignments for each domain: == domain 1 score: 98.6 bits; conditional E-value: 2.7e-32 DUF5917 1 egpfLetLlnkLenlldqslevnLlltsvisrLalypqplLreyLlnpslslqpsvrsLytvLsslkeeleeaakeiedfdellekarkallg 93 eg+fL++L++kL++lldq+++vnL++tsvi+ L+ +++p+L+eyLln +l+l++ +r+L++ L++++++l+ +++++++f++ + +r++l+g FUN_001467-T1 320 EGAFLNMLFKKLQRLLDQPYDVNLQVTSVIALLSQFNHPQLQEYLLNATLPLAQDCRTLHSTLQNVVQDLRGRIQRLPNFQRHVITVRRQLMG 412 79****************************************************************************************986 PP >> KELAA KELAA motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.7 4.0 8.2e-18 6.9e-14 3 28 .. 424 449 .. 422 450 .. 0.93 Alignments for each domain: == domain 1 score: 51.7 bits; conditional E-value: 8.2e-18 KELAA 3 hknllegaiVLEEFCKELAAIAfvks 28 + nlle+aiVLEEFCKELAAIAfvk+ FUN_001467-T1 424 ESNLLEAAIVLEEFCKELAAIAFVKA 449 78***********************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (456 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 786 (0.0307692); expected 510.9 (0.02) Passed bias filter: 652 (0.0255236); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4398.99 // Query: FUN_001467-T2 [L=597] Description: FUN_001467 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-113 377.5 0.2 1.1e-112 377.1 0.2 1.2 1 RAI16-like Retinoic acid induced 16-like protein 9e-29 99.9 2.4 3.6e-28 98.0 2.4 2.1 1 DUF5917 Family of unknown function (DUF5917) 4.3e-14 52.3 4.0 9.6e-14 51.2 4.0 1.6 1 KELAA KELAA motif Domain annotation for each model (and alignments): >> RAI16-like Retinoic acid induced 16-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 377.1 0.2 1.3e-116 1.1e-112 26 360 .] 1 337 [. 1 337 [. 0.98 Alignments for each domain: == domain 1 score: 377.1 bits; conditional E-value: 1.3e-116 RAI16-like 26 mkqevlklfekLlsklrqplLhhesvhRPllkLlrlcgeelssdvekelvqlLnqlcvklrkdpslLelfleekekqqe...keesesaskeeeaa 118 mkq+vl +f ++lsk++qplL+h +v+RP+++L+rl+ge+++++ e+e++q+L+++c+klr+dp+l+++fle+ ++ + +e+ ++ + +++ FUN_001467-T2 1 MKQQVLLFFANILSKMKQPLLPHVNVYRPVHRLIRLSGEVKAAPSENEEIQFLCVVCAKLRQDPYLVNFFLESLGNSPTdlhPAEDFHPPPIKSEG 96 9***********************************************************************988886655566777888889999 PP RAI16-like 119 tekenfllfslLlpyvhre.grlgdkAreaLLllvslasreeelakyliessdlcpllatgLgalYsslpskldpldietiesedwrldeklaked 213 ++k++++l+++Ll++ ++e +r+++kA+e+L+l+ sl+ e+++a+++i ++++c+++a++L+ l++ lp++++pldi ++ + +w+ld+++++ed FUN_001467-T2 97 RDKPDYTLVNSLLNLSKSEdSRIAVKACEGLMLCASLP--EDHAATVIILYTPFCEVMADRLKVLFDHLPKNMEPLDISAVAA-KWGLDHQSDDED 189 9*************************************..*****************************************99.9*********** PP RAI16-like 214 lasfpgkeaLdsFlsslefcnaliqeahsevaealldaikegFLvqvLepsLletseesilavtayLdlilrsitepaLlqeflsFLLgeekspet 309 + sfpgk+ L+sFls+l+++++l++eah+ v +al+ ++e+FL++v+ep+L+++se +i+++ta+L++ ++ +t+p+Llqe+ FLLgee+spe FUN_001467-T2 190 VLSFPGKRRLISFLSWLDYVDQLSKEAHKLVGKALAVGVRERFLQPVMEPALIQQSELGIITATAILRRCVKAVTSPHLLQEICIFLLGEETSPEV 285 ************************************************************************************************ PP RAI16-like 310 se.ddghplldklierinsksdelsivtlrlfetllqlpeediLldLvLrnL 360 + + +h+l+++li+r++++sde+si+tl+lfe+ll++p+e i ++LvLrnL FUN_001467-T2 286 PSnTGDHKLRQTLIQRCDHLSDEVSIETLKLFEALLDKPCEIIFNNLVLRNL 337 **9************************************************8 PP >> DUF5917 Family of unknown function (DUF5917) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.0 2.4 4.2e-32 3.6e-28 1 93 [. 461 553 .. 461 554 .. 0.99 Alignments for each domain: == domain 1 score: 98.0 bits; conditional E-value: 4.2e-32 DUF5917 1 egpfLetLlnkLenlldqslevnLlltsvisrLalypqplLreyLlnpslslqpsvrsLytvLsslkeeleeaakeiedfdellekarkallg 93 eg+fL++L++kL++lldq+++vnL++tsvi+ L+ +++p+L+eyLln +l+l++ +r+L++ L++++++l+ +++++++f++ + +r++l+g FUN_001467-T2 461 EGAFLNMLFKKLQRLLDQPYDVNLQVTSVIALLSQFNHPQLQEYLLNATLPLAQDCRTLHSTLQNVVQDLRGRIQRLPNFQRHVITVRRQLMG 553 79****************************************************************************************986 PP >> KELAA KELAA motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.2 4.0 1.1e-17 9.6e-14 3 28 .. 565 590 .. 563 591 .. 0.93 Alignments for each domain: == domain 1 score: 51.2 bits; conditional E-value: 1.1e-17 KELAA 3 hknllegaiVLEEFCKELAAIAfvks 28 + nlle+aiVLEEFCKELAAIAfvk+ FUN_001467-T2 565 ESNLLEAAIVLEEFCKELAAIAFVKA 590 78***********************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (597 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 726 (0.0284204); expected 510.9 (0.02) Passed bias filter: 668 (0.0261499); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.36s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5878.17 // Query: FUN_001467-T3 [L=717] Description: FUN_001467 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.3e-127 423.7 0.1 9.8e-127 423.3 0.1 1.2 1 RAI16-like Retinoic acid induced 16-like protein 1.2e-28 99.4 2.4 4.7e-28 97.6 2.4 2.1 1 DUF5917 Family of unknown function (DUF5917) 5.6e-14 52.0 4.0 1.2e-13 50.9 4.0 1.5 1 KELAA KELAA motif ------ inclusion threshold ------ 0.06 12.6 0.0 0.085 12.1 0.0 1.1 1 SURNod19 Stress up-regulated Nod 19 Domain annotation for each model (and alignments): >> RAI16-like Retinoic acid induced 16-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 423.3 0.1 1.5e-130 9.8e-127 1 360 [] 78 457 .. 78 457 .. 0.99 Alignments for each domain: == domain 1 score: 423.3 bits; conditional E-value: 1.5e-130 RAI16-like 1 cleyllkekiletlttlgkaeyppgmkqevlklfekLlsklrqplLhhesvhRPllkLlrlcgeelssdvekelvqlLnqlcvklrkdpslLelfl 96 cleyll+ kil+tl+tlg+a++ppgmkq+vl +f ++lsk++qplL+h +v+RP+++L+rl+ge+++++ e+e++q+L+++c+klr+dp+l+++fl FUN_001467-T3 78 CLEYLLQYKILDTLHTLGRADCPPGMKQQVLLFFANILSKMKQPLLPHVNVYRPVHRLIRLSGEVKAAPSENEEIQFLCVVCAKLRQDPYLVNFFL 173 ************************************************************************************************ PP RAI16-like 97 eekekqqe.....................keesesaskeeeaatekenfllfslLlpyvhre.grlgdkAreaLLllvslasreeelakyliessd 170 e+++++++ +e+ ++ + +++ ++k++++l+++Ll++ ++e +r+++kA+e+L+l+ sl+ e+++a+++i +++ FUN_001467-T3 174 ETNSTRTTmpvlpsgenlpslgnsptdlhPAEDFHPPPIKSEGRDKPDYTLVNSLLNLSKSEdSRIAVKACEGLMLCASLP--EDHAATVIILYTP 267 ****9988*******************99777778899999999*************************************..************* PP RAI16-like 171 lcpllatgLgalYsslpskldpldietiesedwrldeklakedlasfpgkeaLdsFlsslefcnaliqeahsevaealldaikegFLvqvLepsLl 266 +c+++a++L+ l++ lp++++pldi ++ + +w+ld+++++ed+ sfpgk+ L+sFls+l+++++l++eah+ v +al+ ++e+FL++v+ep+L+ FUN_001467-T3 268 FCEVMADRLKVLFDHLPKNMEPLDISAVAA-KWGLDHQSDDEDVLSFPGKRRLISFLSWLDYVDQLSKEAHKLVGKALAVGVRERFLQPVMEPALI 362 ****************************99.9**************************************************************** PP RAI16-like 267 etseesilavtayLdlilrsitepaLlqeflsFLLgeekspetse.ddghplldklierinsksdelsivtlrlfetllqlpeediLldLvLrnL 360 ++se +i+++ta+L++ ++ +t+p+Llqe+ FLLgee+spe + + +h+l+++li+r++++sde+si+tl+lfe+ll++p+e i ++LvLrnL FUN_001467-T3 363 QQSELGIITATAILRRCVKAVTSPHLLQEICIFLLGEETSPEVPSnTGDHKLRQTLIQRCDHLSDEVSIETLKLFEALLDKPCEIIFNNLVLRNL 457 *********************************************9************************************************8 PP >> DUF5917 Family of unknown function (DUF5917) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 97.6 2.4 7.3e-32 4.7e-28 1 93 [. 581 673 .. 581 674 .. 0.99 Alignments for each domain: == domain 1 score: 97.6 bits; conditional E-value: 7.3e-32 DUF5917 1 egpfLetLlnkLenlldqslevnLlltsvisrLalypqplLreyLlnpslslqpsvrsLytvLsslkeeleeaakeiedfdellekarkallg 93 eg+fL++L++kL++lldq+++vnL++tsvi+ L+ +++p+L+eyLln +l+l++ +r+L++ L++++++l+ +++++++f++ + +r++l+g FUN_001467-T3 581 EGAFLNMLFKKLQRLLDQPYDVNLQVTSVIALLSQFNHPQLQEYLLNATLPLAQDCRTLHSTLQNVVQDLRGRIQRLPNFQRHVITVRRQLMG 673 79****************************************************************************************986 PP >> KELAA KELAA motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.9 4.0 1.9e-17 1.2e-13 3 28 .. 685 710 .. 683 711 .. 0.93 Alignments for each domain: == domain 1 score: 50.9 bits; conditional E-value: 1.9e-17 KELAA 3 hknllegaiVLEEFCKELAAIAfvks 28 + nlle+aiVLEEFCKELAAIAfvk+ FUN_001467-T3 685 ESNLLEAAIVLEEFCKELAAIAFVKA 710 78***********************8 PP >> SURNod19 Stress up-regulated Nod 19 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 1.3e-05 0.085 37 77 .. 5 46 .. 2 85 .. 0.78 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 1.3e-05 SURNod19 37 lksfdaevvdeagnpvplyetylhhwv.vlkyyakkeakkee 77 +ksf e v+ vpl+et+++hw +++y+ +++ +k FUN_001467-T3 5 IKSFIHEAVEALAPDVPLQETFVFHWKaITNYFIEATDEKVP 46 89************************6256787776665553 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (717 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 667 (0.0261108); expected 510.9 (0.02) Passed bias filter: 614 (0.024036); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 6900.46 // Query: FUN_001470-T1 [L=86] Description: FUN_001470 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (86 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 588 (0.0230182); expected 510.9 (0.02) Passed bias filter: 371 (0.0145234); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 873.73 // Query: FUN_001471-T1 [L=102] Description: FUN_001471 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 796 (0.0311607); expected 510.9 (0.02) Passed bias filter: 605 (0.0236837); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1052.89 // Query: FUN_001472-T1 [L=391] Description: FUN_001472 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-34 118.6 0.3 5.6e-34 117.6 0.1 1.6 2 Methyltransf_31 Methyltransferase domain 1.5e-15 58.0 0.0 3.2e-15 57.0 0.0 1.6 1 Methyltransf_11 Methyltransferase domain 1.6e-14 54.8 0.0 3.7e-14 53.7 0.0 1.7 1 Methyltransf_25 Methyltransferase domain 5.8e-13 49.2 0.1 9.2e-13 48.6 0.1 1.2 1 Ubie_methyltran ubiE/COQ5 methyltransferase family 5.9e-10 40.2 0.1 3.5e-09 37.8 0.0 2.1 2 Methyltransf_12 Methyltransferase domain 1.6e-07 31.8 0.1 6.7e-07 29.8 0.0 1.8 2 PCMT Protein-L-isoaspartate(D-aspartate) O-methyl 4.7e-06 26.9 0.0 7.6e-06 26.2 0.0 1.3 1 Methyltransf_23 Methyltransferase domain 5.3e-05 23.7 0.0 8.6e-05 23.0 0.0 1.3 1 Methyltransf_8 Hypothetical methyltransferase 0.0012 19.1 0.0 0.0023 18.2 0.0 1.5 1 Anamorsin_N Anamorsin, N-terminal 0.0026 18.2 0.1 0.0082 16.6 0.0 1.8 2 FtsJ FtsJ-like methyltransferase 0.0043 17.1 0.0 0.0096 16.0 0.0 1.5 1 MTS Methyltransferase small domain ------ inclusion threshold ------ 0.062 13.8 0.3 8 7.0 0.0 2.6 2 Lac_bphage_repr Lactococcus bacteriophage repressor 0.072 13.1 0.0 0.11 12.4 0.0 1.2 1 PrmA Ribosomal protein L11 methyltransferase (Prm 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 Methyltransf_32 Methyltransferase domain Domain annotation for each model (and alignments): >> Methyltransf_31 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 117.6 0.1 3.1e-37 5.6e-34 3 149 .. 70 223 .. 68 224 .. 0.97 2 ? -2.4 0.0 2.7 5e+03 62 89 .. 277 298 .. 267 350 .. 0.59 Alignments for each domain: == domain 1 score: 117.6 bits; conditional E-value: 3.1e-37 Methyltransf_31 3 kglkvLDlGCGtGrlsfelaeelgpnaevvGiDiseeaiekAre....naeklglk..nvkFeqgdieelpes.ledekfDviisnevlnavpd 89 +g+++LDlG+G+G+++f l +++g+n+ v+G+D+++e++e+A++ +a++ g++ n F++g++e+l e +d++ D+iisn+v n+ +d FUN_001472-T1 70 EGMHILDLGSGSGQDCFVLSKLVGENGFVTGVDMTKEQVEVANKyvnyHAKQFGYSkpNTDFRLGEMEHLSEVgIQDNSMDIIISNCVVNLTAD 163 69******************************************************************************************** PP Methyltransf_31 90 pdkvleeiervlkpggillisdidalaelpaevkeeseeykecvegaitkkelkrlleea 149 ++ vl+e++rvlk gg++++sd+ +++ l +e ++++ ++ ecv+ga +kel +l +e FUN_001472-T1 164 KKIVLKEAHRVLKVGGEVYFSDVYTDTVLSEEARKDEVLWGECVSGALHWKELVKLCKEV 223 ************************************************999999887765 PP == domain 2 score: -2.4 bits; conditional E-value: 2.7 Methyltransf_31 62 dieelpesledekfDviisnevlnavpd 89 i e p e+ kfDv +++l +p FUN_001472-T1 277 TIKESP---EELKFDV---RNTLTKSPK 298 455555...2366777...334422222 PP >> Methyltransf_11 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.0 0.0 1.7e-18 3.2e-15 1 95 [] 75 183 .. 75 183 .. 0.92 Alignments for each domain: == domain 1 score: 57.0 bits; conditional E-value: 1.7e-18 Methyltransf_11 1 LdvGcGtGllaealarlg...arvtgvDlspemlelakekakkegl........vefvqadaedlp...fpdesfDlvlssevlhhvedpekal 80 Ld+G+G+G+ + l++l+ + vtgvD+++e++e+a++ ++ +f+ +++e+l ++d+s+D+++s+ v++ ++d + +l FUN_001472-T1 75 LDLGSGSGQDCFVLSKLVgenGFVTGVDMTKEQVEVANKYVNYHAKqfgyskpnTDFRLGEMEHLSevgIQDNSMDIIISNCVVNLTADKKIVL 168 8**************8888999***************887777666789999999********974456************************* PP Methyltransf_11 81 reiaRvLkpgGllvi 95 +e++RvLk gG +++ FUN_001472-T1 169 KEAHRVLKVGGEVYF 183 ***********9986 PP >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.7 0.0 2e-17 3.7e-14 1 97 [] 74 179 .. 74 179 .. 0.84 Alignments for each domain: == domain 1 score: 53.7 bits; conditional E-value: 2e-17 Methyltransf_25 1 vLdlGcGtGrlalelakrlg.eaevtgvDlseemlerareraae.......eglnvefvqgdaedlp...fedgsfdlvvssga.lhhlsdedl 82 +LdlG G+G+ + l+k +g ++ vtgvD+ +e++e+a++ ++ +++n +f+ g++e+l+ +d+s+d+++s ++ +++++ d FUN_001472-T1 74 ILDLGSGSGQDCFVLSKLVGeNGFVTGVDMTKEQVEVANKYVNYhakqfgySKPNTDFRLGEMEHLSevgIQDNSMDIIIS-NCvVNLTA--DK 164 8******************88******************877654433443445***********985557**********.67355554..56 PP Methyltransf_25 83 eaalaeiarvLkpgG 97 + +l+e++rvLk gG FUN_001472-T1 165 KIVLKEAHRVLKVGG 179 789**********99 PP >> Ubie_methyltran ubiE/COQ5 methyltransferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.6 0.1 5e-16 9.2e-13 45 151 .. 68 183 .. 63 195 .. 0.86 Alignments for each domain: == domain 1 score: 48.6 bits; conditional E-value: 5e-16 Ubie_methyltran 45 vkrgakvlDvagGtgDltfklsdsvgekgkvvvlDinenmLkvgekklkeegks......nieflqanaeeLpf...eddsfDvvtisfGlrn. 128 ++g ++lD+ +G+g f ls+ vge+g v+++D+ ++ ++v++k ++ ++k+ n +f ++ e+L + +d+s+D++ is + n FUN_001472-T1 68 ALEGMHILDLGSGSGQDCFVLSKLVGENGFVTGVDMTKEQVEVANKYVNYHAKQfgyskpNTDFRLGEMEHLSEvgiQDNSMDII-ISNCVVNl 160 57899****************************************988777766666799*********9987533389****98.56666661 PP Ubie_methyltran 129 vtDklkaLkeifrvlkpGGrlvv 151 ++Dk+ +Lke++rvlk+GG+++ FUN_001472-T1 161 TADKKIVLKEAHRVLKVGGEVYF 183 679999**************985 PP >> Methyltransf_12 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.8 0.0 1.9e-12 3.5e-09 1 97 [. 75 180 .. 75 181 .. 0.88 2 ? -0.3 0.0 1.5 2.7e+03 47 76 .. 281 312 .. 265 322 .. 0.76 Alignments for each domain: == domain 1 score: 37.8 bits; conditional E-value: 1.9e-12 Methyltransf_12 1 LeiGcGtGallralleal.pgleyvgvDispaaleaarerlaalerldaarveleqldlaeeepe............sfDvvvasnvlhhladl 81 L++G+G+G+ ++ l + ++ ++gvD +++++ e +++ +++a+++ +++ + + + +e s D++++++v+ +ad+ FUN_001472-T1 75 LDLGSGSGQDCFVLSKLVgENGFVTGVDMTKEQV----EVANKYVNYHAKQFGYSKPNTDFRLGEmehlsevgiqdnSMDIIISNCVVNLTADK 164 8*****************9999999*********....5555566666677777777777777777778889********************** PP Methyltransf_12 82 eevlrnlrrlLkpgGv 97 + vl++++r+Lk gG FUN_001472-T1 165 KIVLKEAHRVLKVGGE 180 **************96 PP == domain 2 score: -0.3 bits; conditional E-value: 1.5 Methyltransf_12 47 daarveleqldlaeeepe..sfDvvvasnvlh 76 + +++++++++ + p+ s Dv+++++v FUN_001472-T1 281 SPEELKFDVRNTLTKSPKtvSADVATVLSVSR 312 45677788888777777789999999998865 PP >> PCMT Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.0 3.7e-10 6.7e-07 73 123 .. 70 120 .. 43 137 .. 0.90 2 ? -0.8 0.0 0.81 1.5e+03 54 83 .. 151 180 .. 137 198 .. 0.69 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 3.7e-10 PCMT 73 kgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakknlkkldl 123 +g+++L++GsGsG vl++lvge+g v +++ +ke ve a+k ++ ++ FUN_001472-T1 70 EGMHILDLGSGSGQDCFVLSKLVGENGFVTGVDMTKEQVEVANKYVNYHAK 120 79******************************************9988765 PP == domain 2 score: -0.8 bits; conditional E-value: 0.81 PCMT 54 atiSaphmvalalellelkkgarvLevGsG 83 iS+ + +a + + lk+ rvL vG+ FUN_001472-T1 151 IIISNCVVNLTADKKIVLKEAHRVLKVGGE 180 456666666666666779999999999964 PP >> Methyltransf_23 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 4.2e-09 7.6e-06 19 124 .. 67 194 .. 58 227 .. 0.72 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 4.2e-09 Methyltransf_23 19 klkspgrvLDiGcGtGiflell....reegfkvvgvDpspeaiera.nlknvvkkqfdeeeaaepag..................kydvIvlre 89 + +++ +LD+G+G+G + +l e+g v+gvD e++e a + +n + kqf + ++p+ d+I+++ FUN_001472-T1 67 EALEGMHILDLGSGSGQDCFVLsklvGENG-FVTGVDMTKEQVEVAnKYVNYHAKQF---GYSKPNTdfrlgemehlsevgiqdnSMDIIISNC 156 4568999**********9999943333344.489*******9999874444444444...3333333555556666666666666********* PP Methyltransf_23 90 vlehvkdppallrqiaallkpgGllllstplasl...e 124 v + d +l+ +++ lk gG +++s++ + e FUN_001472-T1 157 VVNLTADKKIVLKEAHRVLKVGGEVYFSDVYTDTvlsE 194 *****************************866554431 PP >> Methyltransf_8 Hypothetical methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 4.7e-08 8.6e-05 113 160 .. 139 187 .. 95 199 .. 0.82 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 4.7e-08 Methyltransf_8 113 makvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaevk 160 +++v ++d+s+d+++ c+ ++ + + lkea+rvlkvGG ++ ++v FUN_001472-T1 139 LSEVGIQDNSMDIIISnCVVNLTADKKIVLKEAHRVLKVGGEVYFSDVY 187 47899********99549999**********************999885 PP >> Anamorsin_N Anamorsin, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 1.3e-06 0.0023 35 101 .. 132 196 .. 101 206 .. 0.83 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.3e-06 Anamorsin_N 35 svEnverLllsshkaSsfdvvlsgllapsalihsseiLaeiariLkpgGklvlkepvttasenaskl 101 ++ ++e L++ ++ s d+++s ++ + + ++ +L+e r+Lk gG+++++++ t+++ +++ FUN_001472-T1 132 RLGEMEHLSEVGIQDNSMDIIISNCVVN-LTADKKIVLKEAHRVLKVGGEVYFSDVYTDTV-LSEEA 196 5678999******************997.668999*******************9887654.34444 PP >> FtsJ FtsJ-like methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 4.5e-06 0.0082 21 106 .. 70 163 .. 45 182 .. 0.80 2 ? -1.7 0.0 1.8 3.3e+03 67 109 .. 271 314 .. 254 319 .. 0.62 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 4.5e-06 FtsJ 21 kgkvvlDlGaapGgfsqvllervga.gkvvavDlgpgql..ekprkdpgvtfi........eqgdirdleteekleell.gkkvdlvlsDgspfis 104 +g+++lDlG++ G+ + vl++ vg+ g v++vD+ + q+ + v+ + ++d+r e e + e + ++ +d+++s + + FUN_001472-T1 70 EGMHILDLGSGSGQDCFVLSKLVGEnGFVTGVDMTKEQVevA--N--KYVNYHakqfgyskPNTDFRLGEMEHLSEVGIqDNSMDIIISNCVVNLT 161 7899*******************999********99988542..3..3333333344777779999999988888877778999999999887777 PP FtsJ 105 gn 106 + FUN_001472-T1 162 AD 163 65 PP == domain 2 score: -1.7 bits; conditional E-value: 1.8 FtsJ 67 vtfieqgdirdleteekle..ellgkkvdlvlsDgspfisgnkvl 109 v+++ +g i++ e k++ ++l k +++v +D++ s+ + FUN_001472-T1 271 VVTY-KGTIKESPEELKFDvrNTLTKSPKTVSADVATVLSVSRFA 314 4555.6666554444433332444688999999999777766655 PP >> MTS Methyltransferase small domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 5.3e-06 0.0096 32 136 .. 71 182 .. 63 195 .. 0.79 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 5.3e-06 MTS 32 sgkvlDlGcGaGvlglalakespeae.vtlvdvnarAvesarenlkankle.........aevvasdvlseve..dkkfdliisNPPfhagkatel 115 ++lDlG+G G +l+k e+ vt vd ++ ve+a++ ++ ++ + ++ + + lsev d+++d+iisN + + FUN_001472-T1 71 GMHILDLGSGSGQDCFVLSKLVGENGfVTGVDMTKEQVEVANKYVNYHAKQfgyskpntdFRLGEMEHLSEVGiqDNSMDIIISNCVVNLTAD--- 163 5689****************9999988***************97776665555777774444555566676644499********86665555... PP MTS 116 avaqeliaeAaeaLksgGell 136 + +++eA+++Lk gGe++ FUN_001472-T1 164 --KKIVLKEAHRVLKVGGEVY 182 ..3445789999999999986 PP >> Lac_bphage_repr Lactococcus bacteriophage repressor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.035 65 35 49 .] 9 23 .. 4 23 .. 0.89 2 ? 7.0 0.0 0.0044 8 26 42 .. 34 50 .. 30 53 .. 0.91 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.035 Lac_bphage_repr 35 VKkalkailGkkLeD 49 VK+ +k +Gk+L+D FUN_001472-T1 9 VKENVKDYYGKRLKD 23 7************98 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0044 Lac_bphage_repr 26 FDGkPltDeVKkalkai 42 FDGk ++ VK+alk++ FUN_001472-T1 34 FDGKSMAPAVKTALKLV 50 ***************87 PP >> PrmA Ribosomal protein L11 methyltransferase (PrmA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 6.1e-05 0.11 161 260 .. 70 185 .. 64 200 .. 0.72 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 6.1e-05 PrmA 161 egesvlDvGtGSGiLaiaalklgakk..vvgvDiDevAvkaakeNaelN.......kveeqlev....ylseellkeekadvvvaNILaevlie.. 241 eg ++lD+G GSG +kl ++ v+gvD+ + v++a++ +++ k ++ +++ +lse ++++++d++++N + + + FUN_001472-T1 70 EGMHILDLGSGSGQDCFVLSKLVGENgfVTGVDMTKEQVEVANKYVNYHakqfgysKPNTDFRLgemeHLSEVGIQDNSMDIIISNCVVNLTADkk 165 56789********98888888765543499***********98755544445554433334444444445666667999*******9888764322 PP PrmA 242 .laedikellkpggllilSG 260 +++++ ++lk gg + +S FUN_001472-T1 166 iVLKEAHRVLKVGGEVYFSD 185 26778888888888888775 PP >> Methyltransf_32 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.00016 0.29 24 72 .. 69 114 .. 43 154 .. 0.78 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00016 Methyltransf_32 24 keeltlvDvGaGkgYLgfilydllkekelkvrvlgidvreelvekaeel 72 e ++++D+G+G g f+l++l+ e ++ v+g+d+ +e ve a++ FUN_001472-T1 69 LEGMHILDLGSGSGQDCFVLSKLVGE---NGFVTGVDMTKEQVEVANKY 114 56789*****************5544...569************99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (391 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 746 (0.0292034); expected 510.9 (0.02) Passed bias filter: 614 (0.024036); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3832.31 // Query: FUN_001473-T1 [L=1092] Description: FUN_001473 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-100 336.2 1.9 2e-100 335.5 0.4 2.2 2 TPR_XPO7 Exportin-7-like, TPR repeats 7.4e-13 48.8 0.9 4.6e-12 46.2 0.1 2.9 2 IBN_N Importin-beta N-terminal domain Domain annotation for each model (and alignments): >> TPR_XPO7 Exportin-7-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 0.61 7.8e+03 22 55 .. 4 37 .. 3 46 .. 0.84 2 ! 335.5 0.4 1.5e-104 2e-100 2 238 .. 418 653 .. 417 656 .. 0.97 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 0.61 TPR_XPO7 22 qqLeqlsticRfeYektsellvklfdelaqeYqe 55 q++ ql +c+ Ye+t ++ ++ +++++++++ FUN_001473-T1 4 QEIAQLDLLCKQLYEATDTATRNAAERALSTFTN 37 7788999999999999999999998888888876 PP == domain 2 score: 335.5 bits; conditional E-value: 1.5e-104 TPR_XPO7 2 vaavvdegledpLddeeslqqqLeqlsticRfeYektsellvklfdelaqeYqellssaeeaekeeleviegkLtWlvyiigaiiggrqsssssee 97 v+av+++++edpLdd++++qqqL+qlst++R+eYekt++ll++lfd++aq+Yqel++s++ a++++++++eg+LtWlvyiig++iggr+s+s++ee FUN_001473-T1 418 VEAVIRDNVEDPLDDTGTVQQQLDQLSTFGRCEYEKTCQLLISLFDQAAQSYQELVQSTS-ASTNDMAIQEGRLTWLVYIIGSVIGGRVSYSTTEE 512 7899****************************************************9999.*********************************** PP TPR_XPO7 98 hdalDgeLvarvlqlmqltdsrlqqqrskekLelAiLsffeqfRkvyvgdqaqksskvYarLsellgledelavlnvivrkiitnLklwgeseevi 193 dalDgeLv+rvlqlm+ltds+l+q++s ekLel+iLsffeqfRk+yvgdqaqksskvY+rLse+lgl+de++vl+v++ kiitn+k+wg+se++i FUN_001473-T1 513 YDALDGELVCRVLQLMNLTDSQLSQRGS-EKLELSILSFFEQFRKMYVGDQAQKSSKVYRRLSERLGLHDESNVLSVFMGKIITNMKFWGSSEAII 607 **************************98.******************************************************************* PP TPR_XPO7 194 ektLsLlsdLasgyssv.kkLlkldevqfllsnhtsehFpFLgsee 238 +ktL+LlsdL++gy v +kl++vqf+l+nhtsehFpFLg ++ FUN_001473-T1 608 SKTLQLLSDLSIGYPFVfVDDFKLEAVQFVLNNHTSEHFPFLGIHA 653 **************87625679********************9765 PP >> IBN_N Importin-beta N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 0.1 3.6e-16 4.6e-12 1 73 [] 28 93 .. 28 93 .. 0.98 2 ? -1.7 0.1 0.32 4.1e+03 7 27 .. 882 902 .. 878 906 .. 0.79 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 3.6e-16 IBN_N 1 AekqLeqlekspgflskllqilsnsesplevRqlAalyLknlitkkWsdeeekslpeeekeqIknnllnllls 73 Ae++L + +sp++l+k++++l++++s+ +++++Aa+ L++li+k+ + +++ e++ +++n++l++l++ FUN_001473-T1 28 AERALSTFTNSPDCLTKCQYLLERGNSS-YSQLIAASSLTRLISKN-T-----TISVEQRLHMRNYVLTYLGT 93 9***************************.****************9.9.....*****************985 PP == domain 2 score: -1.7 bits; conditional E-value: 0.32 IBN_N 7 qlekspgflskllqilsnses 27 + k+ ++ ++ll+il++++ FUN_001473-T1 882 EYPKLSQSYYALLEILAQDHM 902 5557889999*******9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1092 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 703 (0.0275201); expected 510.9 (0.02) Passed bias filter: 550 (0.0215306); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.40s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 10372.77 // Query: FUN_001474-T1 [L=336] Description: FUN_001474 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.1 12.9 0.2 0.19 12.0 0.2 1.4 1 FAM176 FAM176 family Domain annotation for each model (and alignments): >> FAM176 FAM176 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.2 7.5e-06 0.19 32 103 .. 4 73 .. 2 87 .. 0.59 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 7.5e-06 FAM176 32 vGLvltLcllViriscrkdlkklakkkkelkeeseedeedseeeeeeeeedsseseikdeltel...ekssefer 103 v L+l L++lV+ ++d +k+ ++++e+++e+e++++++ + e+ ++ ++++++++ +++++f + FUN_001474-T1 4 VALLLCLTILVALTEAAPDPSKRLPDQQEKQDEQEQQRDQQGQ-----ESAPATDQVQQPMANYvgaDMNQQFMA 73 5689999999999999988887666666666665444333333.....333333333333333223355555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1629 (0.0637698); expected 510.9 (0.02) Passed bias filter: 730 (0.028577); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 3276.58 // Query: FUN_001476-T1 [L=626] Description: FUN_001476 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-122 405.4 0.7 1.3e-121 404.9 0.7 1.1 1 COE1_DBD Transcription factor COE1 DNA-binding domain 6.1e-28 96.8 0.3 1.3e-27 95.8 0.3 1.6 1 COE1_HLH Transcription factor COE1 helix-loop-helix domain 4.1e-12 46.4 2.2 9.5e-12 45.2 0.1 2.4 2 TIG IPT/TIG domain ------ inclusion threshold ------ 0.039 14.3 0.0 0.065 13.5 0.0 1.3 1 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> COE1_DBD Transcription factor COE1 DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 404.9 0.7 2e-125 1.3e-121 24 230 .. 23 227 .. 5 228 .. 0.97 Alignments for each domain: == domain 1 score: 404.9 bits; conditional E-value: 2e-125 COE1_DBD 24 svaatssvglarahfekqppsnlrksnffhfvlalydrngqpvevertafidfvekekekedektnngihyrlqllysnglrteqdlyvrlidsvt 119 s++ ts+ +larahfekqpp nlrksnffhfvla+yd+ gq+ve+er+ f+ fve+ +++++++ng yrlqllys g+r+eqd+++rl++svt FUN_001476-T1 23 SNQVTSGCSLARAHFEKQPPPNLRKSNFFHFVLAFYDHSGQAVEIERAGFLGFVEH--LPDQKNVRNGASYRLQLLYSSGIRSEQDIFIRLVNSVT 116 456788999***********************************************..9************************************* PP COE1_DBD 120 kqaiiyegqdknpemcrvllthevmcsrccdkkscgnrnetpsdpviidrfflkfflkcnqnclknagnprdmrrfqvavsttvsvegevlavsdn 215 kq i+yegqdknpemcrvl+thevmcsrcc+kkscgn+netpsdpviidr+flkfflkcnqnclknagnprdmrrfqv vs++ ++ +la+sdn FUN_001476-T1 117 KQPIVYEGQDKNPEMCRVLMTHEVMCSRCCEKKSCGNKNETPSDPVIIDRYFLKFFLKCNQNCLKNAGNPRDMRRFQVNVSASPDPVSGLLACSDN 212 ************************************************************************************************ PP COE1_DBD 216 mfvhnnskhgrrarr 230 mfvhnnskhgr++r+ FUN_001476-T1 213 MFVHNNSKHGRKSRK 227 **************8 PP >> COE1_HLH Transcription factor COE1 helix-loop-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.8 0.3 2e-31 1.3e-27 1 43 [. 320 362 .. 320 363 .. 0.97 Alignments for each domain: == domain 1 score: 95.8 bits; conditional E-value: 2e-31 COE1_HLH 1 lnEPtidyGFqRLqKlvPrhPGDperLpKeiILkRAAdlaEal 43 l EPtidyGFqRL+Kl+PrhPGDpe+LpKeiILkRAAdl Ea+ FUN_001476-T1 320 LCEPTIDYGFQRLAKLIPRHPGDPEKLPKEIILKRAADLLEAV 362 68***************************************98 PP >> TIG IPT/TIG domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.2 0.1 1.5e-15 9.5e-12 1 84 [] 235 317 .. 235 317 .. 0.95 2 ? -0.0 0.3 0.2 1.3e+03 20 40 .. 403 431 .. 384 455 .. 0.59 Alignments for each domain: == domain 1 score: 45.2 bits; conditional E-value: 1.5e-15 TIG 1 PvitsisPssgpasGgttitItGsnFgtdssdlsvtiggtectvisvssttivcetppgt.sglvsvsvtvgg.vglsssnvtfty 84 P+i++i P+ g+a Ggt++ I G nF ++l+v +g+ + ++++++ i++++pp + +++v+v++ +++ + ++++ f y FUN_001476-T1 235 PTIKAICPNEGWAIGGTNVVIIGENF---FDGLQVVFGSLIVWSEFITPHAIRVQAPPRPfPSTVEVTLMYRNkQFCKTAPGRFIY 317 9*************************...********************************************8888888887766 PP == domain 2 score: -0.0 bits; conditional E-value: 0.2 TIG 20 tItGsnF........gtdssdlsvtiggt 40 tIt +++ t+++++sv gg+ FUN_001476-T1 403 TITPDGLnnggpyvtITNPDGTSVVYGGS 431 22222223333333334444444444444 PP >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 1e-05 0.065 19 49 .. 328 359 .. 324 362 .. 0.88 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1e-05 HLH 19 afdeLrellP.tlppdkKlsKaeiLrlAieYI 49 +f++L +l+P + ++ +Kl K iL++A + + FUN_001476-T1 328 GFQRLAKLIPrHPGDPEKLPKEIILKRAADLL 359 7*********8888888***********9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (626 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 625 (0.0244666); expected 510.9 (0.02) Passed bias filter: 390 (0.0152672); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.42s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 6073.30 // Query: FUN_001477-T1 [L=506] Description: FUN_001477 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-23 83.1 13.2 2.6e-05 25.0 2.1 7.4 8 TPR_19 Tetratricopeptide repeat 4.8e-23 79.8 13.5 0.025 15.8 0.1 9.5 9 TPR_14 Tetratricopeptide repeat 4.8e-13 49.6 6.2 4.8e-13 49.6 6.2 4.3 4 SRP_TPR_like Putative TPR-like repeat 8.6e-13 48.9 20.5 2e-06 28.5 0.8 6.3 6 ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3e-11 43.0 25.9 0.003 18.1 0.1 9.7 9 TPR_2 Tetratricopeptide repeat 4.9e-11 43.0 17.9 0.017 16.2 0.2 9.5 10 TPR_6 Tetratricopeptide repeat 2.6e-10 40.8 19.3 0.0024 18.5 1.1 7.6 7 TPR_12 Tetratricopeptide repeat 5.2e-09 36.0 27.3 0.0018 18.8 0.1 9.0 9 TPR_8 Tetratricopeptide repeat 1.8e-08 35.3 5.5 0.00033 21.5 0.1 3.9 3 BTAD Bacterial transcriptional activator domain 1.2e-06 28.6 10.6 0.065 13.8 0.1 7.3 7 TPR_7 Tetratricopeptide repeat 1.8e-06 27.9 9.0 0.00014 21.7 1.4 3.5 3 TPR_MalT MalT-like TPR region 2e-06 28.4 18.3 0.037 14.5 3.2 5.1 4 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 3.1e-06 27.6 17.9 0.00096 19.4 3.1 5.2 5 ARM_TT21_N Tetratricopeptide repeat protein 21 N-terminal 3.3e-06 27.9 11.4 0.065 14.0 0.0 6.3 6 ARM_TT21_5th TT21 fifth ARM repeats domain 6.6e-06 26.5 3.5 16 6.5 0.0 8.0 9 PPR PPR repeat 7.3e-06 26.3 0.3 7.3e-06 26.3 0.3 4.1 4 TPR_21 Tetratricopeptide repeat-like domain 3.3e-05 24.3 1.2 2.2 8.8 0.0 5.9 7 TPR_9 Tetratricopeptide repeat 4.1e-05 24.4 8.2 2.6 9.1 0.1 7.4 8 TPR_16 Tetratricopeptide repeat 8.9e-05 23.2 0.0 2.3 9.6 0.0 4.8 3 TPR_4 Tetratricopeptide repeat 9.1e-05 22.6 23.3 0.0019 18.4 0.2 7.9 8 TPR_1 Tetratricopeptide repeat 0.00016 22.1 2.7 0.3 11.5 0.2 3.8 3 TPR_24 Fungal tetratrico peptide repeats 0.00029 21.3 6.7 10 7.1 0.0 7.5 8 TPR_17 Tetratricopeptide repeat 0.0037 18.3 17.1 3 8.9 0.8 6.3 5 TPR-S Tetratricopeptide Repeats-Sensor 0.0042 16.3 12.0 0.17 11.1 0.2 4.4 5 Iml2-TPR_39 Iml2/Tetratricopeptide repeat protein 39 0.0071 15.6 4.0 0.14 11.3 0.3 3.0 3 PknG_TPR Protein kinase G tetratricopeptide repeat 0.0085 16.5 13.0 0.86 10.2 0.1 7.0 8 TPR_10 Tetratricopeptide repeat ------ inclusion threshold ------ 0.011 16.3 2.2 0.043 14.4 0.2 3.2 2 ANAPC5 Anaphase-promoting complex subunit 5 0.071 13.5 0.2 0.89 10.0 0.0 2.5 2 Cdc6_lid Cdc6 AAA+ ATPase-type lid domain 0.094 13.3 1.2 29 5.3 0.0 3.7 3 HemY_N HemY protein N-terminus 0.11 12.9 0.1 14 6.0 0.0 3.3 2 ATP13 Mitochondrial ATPase expression 0.12 13.0 7.3 25 5.6 0.1 4.9 5 TPR_P4H Prolyl 4-hydroxylase peptide-substrate-binding 0.13 12.8 5.6 0.22 12.1 0.1 3.2 3 DUF4363 Domain of unknown function (DUF4363) 0.25 11.9 1.6 2.2 8.9 0.3 3.0 2 Rapsyn_N Rapsyn N-terminal myristoylation and linker reg 0.49 11.1 4.0 4.1 8.2 0.0 4.0 4 Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat 0.87 10.5 9.4 5.5 7.9 0.2 5.0 6 TPR_Slam Surface lipoprotein assembly modifier, N-termin 1.9 8.8 7.9 20 5.6 0.3 3.9 4 DUF4919 Domain of unknown function (DUF4919) 4 8.2 5.4 8.3 7.2 1.6 3.3 2 TPR_3 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 1.6e-05 0.011 5 57 .. 25 77 .. 23 85 .. 0.93 2 ? 3.7 0.2 0.16 1.1e+02 27 55 .. 80 108 .. 77 118 .. 0.79 3 ? 2.1 0.4 0.5 3.5e+02 5 34 .. 92 118 .. 88 144 .. 0.49 4 ! 25.0 2.1 3.7e-08 2.6e-05 3 63 .. 195 264 .. 193 268 .. 0.92 5 ? -1.4 0.0 6.5 4.5e+03 36 57 .. 315 336 .. 313 339 .. 0.87 6 ! 14.1 0.1 9.4e-05 0.065 3 52 .. 350 400 .. 348 406 .. 0.83 7 ! 8.7 0.0 0.0044 3 27 58 .. 408 439 .. 403 444 .. 0.88 8 ! 15.6 0.0 3e-05 0.021 2 35 .. 460 493 .. 459 494 .. 0.96 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 1.6e-05 TPR_19 5 gdydeAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpd 57 ++++Al++ ++l+e Pd+ ea+ + +l+++ + eA +++ +p++ d FUN_001477-T1 25 RNFEKALKIANKILQEKPDDKEAYHCKVICLIHQSCFREALDVINSAPKKGVD 77 689*********************************************99877 PP == domain 2 score: 3.7 bits; conditional E-value: 0.16 TPR_19 27 arllLArallalgrldeAealLaalpaad 55 ++ A l++l++ eA ++L+a+ + + FUN_001477-T1 80 LQFEKAYSLYRLNKTQEALNTLNAIEELK 108 6666788899*************998765 PP == domain 3 score: 2.1 bits; conditional E-value: 0.5 TPR_19 5 gdydeAlalLeqalaedPdnaearllLAra 34 ++++eAl+ L ++ ++ + e+++ ++ FUN_001477-T1 92 NKTQEALNTLNAIEELKEHEKELKA---QV 118 3444454444444444444444444...55 PP == domain 4 score: 25.0 bits; conditional E-value: 3.7e-08 TPR_19 3 aegdydeAlalLeqalaedPd.........naearllLArallalgrldeAealLaalpaadpddpeyaa 63 ae+++++A +l+e+ l dPd +r+ LA ++ +g+ deA++l +++++ +p+d ++aa FUN_001477-T1 195 AEEKLKKAEELCEKSLRDDPDigeeefeaeMGIVRVQLAYVYQLQGKNDEAQKLYNQVLKSKPNDLALAA 264 899**********************99999999*******************************866655 PP == domain 5 score: -1.4 bits; conditional E-value: 6.5 TPR_19 36 lalgrldeAealLaalpaadpd 57 +++++l++ ++l ++l a++p+ FUN_001477-T1 315 FHTNQLEACRNLTSTLEAKYPE 336 5789**********99999987 PP == domain 6 score: 14.1 bits; conditional E-value: 9.4e-05 TPR_19 3 aegdydeAlalLeq.alaedPdnaearllLArallalgrldeAealLaalp 52 e++ ++A+++L++ a ++ ++l+L++++la+g++ eA ++L + FUN_001477-T1 350 REKQSAKAVEVLKNyAECHEDSAMNVKLTLVQLYLAQGNIGEACNTLRSVK 400 678889999999995555666699*******************99998765 PP == domain 7 score: 8.7 bits; conditional E-value: 0.0044 TPR_19 27 arllLArallalgrldeAealLaalpaadpdd 58 + +L+ ++ + g++++A +L+++ ++++++ FUN_001477-T1 408 VVSALVTLYSHIGDVSAAVDILDEAVEHAQKN 439 6678999*********************9986 PP == domain 8 score: 15.6 bits; conditional E-value: 3e-05 TPR_19 2 laegdydeAlalLeqalaedPdnaearllLAral 35 l+ g+++eA+ +Le++++edP++ ++ L++a+ FUN_001477-T1 460 LQHGRAKEAVDMLEKLHKEDPTDVKTLAQLIKAY 493 789****************************998 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.0 0.0023 1.6 15 41 .. 25 51 .. 19 54 .. 0.90 2 ? 4.4 0.1 0.17 1.1e+02 2 29 .. 79 106 .. 78 115 .. 0.85 3 ? 8.0 0.1 0.011 7.8 6 34 .. 114 142 .. 109 145 .. 0.88 4 ? 4.3 0.1 0.18 1.2e+02 10 33 .. 192 215 .. 191 218 .. 0.88 5 ! 15.8 0.1 3.6e-05 0.025 5 37 .. 230 262 .. 228 267 .. 0.90 6 ? 6.6 0.1 0.032 22 5 34 .. 342 371 .. 341 373 .. 0.88 7 ? 7.4 0.0 0.018 12 3 26 .. 375 398 .. 373 403 .. 0.89 8 ! 8.8 0.0 0.0064 4.4 6 36 .. 411 441 .. 406 445 .. 0.85 9 ! 13.7 0.0 0.00016 0.11 11 43 .. 459 491 .. 456 492 .. 0.90 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.0023 TPR_14 15 GdpdeAlelleralaldPddpeawlal 41 ++++Al++++++l+ Pdd ea++ + FUN_001477-T1 25 RNFEKALKIANKILQEKPDDKEAYHCK 51 689********************9876 PP == domain 2 score: 4.4 bits; conditional E-value: 0.17 TPR_14 2 eawlalarallalGdpdeAlellerala 29 e++ a+ l +l++++eAl l+++ + FUN_001477-T1 79 ELQFEKAYSLYRLNKTQEALNTLNAIEE 106 6788899****************99855 PP == domain 3 score: 8.0 bits; conditional E-value: 0.011 TPR_14 6 alarallalGdpdeAlelleralaldPdd 34 + a++l +l d++++l+l++++++ dd FUN_001477-T1 114 LKAQVLYRLEDYHACLKLYKDLIKNSQDD 142 5699******************9987776 PP == domain 4 score: 4.3 bits; conditional E-value: 0.18 TPR_14 10 allalGdpdeAlelleralaldPd 33 +++a ++++A+el e+ l+ dPd FUN_001477-T1 192 IEAAEEKLKKAEELCEKSLRDDPD 215 57889999************9998 PP == domain 5 score: 15.8 bits; conditional E-value: 3.6e-05 TPR_14 5 lalarallalGdpdeAlelleralaldPddpea 37 +la+++ +G+ deA +l+++ l+ P+d ++ FUN_001477-T1 230 VQLAYVYQLQGKNDEAQKLYNQVLKSKPNDLAL 262 79***************************9876 PP == domain 6 score: 6.6 bits; conditional E-value: 0.032 TPR_14 5 lalarallalGdpdeAlelleralaldPdd 34 l++a +l + ++ ++A+e+l+ + + + d+ FUN_001477-T1 342 LMRASLLHREKQSAKAVEVLKNYAECHEDS 371 5799*******************8877765 PP == domain 7 score: 7.4 bits; conditional E-value: 0.018 TPR_14 3 awlalarallalGdpdeAleller 26 + l l++++la+G+ eA l++ FUN_001477-T1 375 VKLTLVQLYLAQGNIGEACNTLRS 398 5689***************99986 PP == domain 8 score: 8.8 bits; conditional E-value: 0.0064 TPR_14 6 alarallalGdpdeAlelleralaldPddpe 36 al+ ++ Gd ++A+++l++a+++ ++ + FUN_001477-T1 411 ALVTLYSHIGDVSAAVDILDEAVEHAQKNKD 441 79999******************98877655 PP == domain 9 score: 13.7 bits; conditional E-value: 0.00016 TPR_14 11 llalGdpdeAlelleralaldPddpeawlalar 43 l+ G+ +eA+++le++++ dP+d + +l++ FUN_001477-T1 459 KLQHGRAKEAVDMLEKLHKEDPTDVKTLAQLIK 491 6899*********************99999987 PP >> SRP_TPR_like Putative TPR-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.6 6.2 7e-16 4.8e-13 8 106 .. 37 154 .. 23 156 .. 0.82 2 ? -1.1 0.1 4.2 2.9e+03 42 68 .. 230 256 .. 196 287 .. 0.71 3 ? 0.4 0.1 1.4 9.4e+02 44 92 .. 344 398 .. 269 402 .. 0.65 4 ? 1.8 0.1 0.5 3.4e+02 68 105 .. 448 487 .. 431 492 .. 0.68 Alignments for each domain: == domain 1 score: 49.6 bits; conditional E-value: 7e-16 SRP_TPR_like 8 ilrlespelkrf.........kvvalikldkykeALkylekgs.........fEkaYilYklkkykkalkilkklese..klkvlksqvlYflgyy 83 il+ kv++li+ ++eAL +++ + fEkaY lY+l+k + al+ l+ +e+ + k lk+qvlY+l+ y FUN_001477-T1 37 ILQE-------KpddkeayhcKVICLIHQSCFREALDVINSAPkkgvdielqFEKAYSLYRLNKTQEALNTLNAIEELkeHEKELKAQVLYRLEDY 125 4333.......3333333355******************9988899*****************************986448899************ PP SRP_TPR_like 84 nkA...yklL...skvkkddeivvnlqAm 106 + yk L s+ ++ de++ nl+A+ FUN_001477-T1 126 HAClklYKDLiknSQDDYGDERETNLAAV 154 99877788887777778889******998 PP == domain 2 score: -1.1 bits; conditional E-value: 4.2 SRP_TPR_like 42 fEkaYilYklkkykkalkilkklesek 68 + aY++ k a+k+ +++ ++k FUN_001477-T1 230 VQLAYVYQLQGKNDEAQKLYNQVLKSK 256 556676666666777777666665544 PP == domain 3 score: 0.4 bits; conditional E-value: 1.4 SRP_TPR_like 44 kaYilYklkkykkalkilkklese......klkvlksqvlYflgyynkAyklLsk 92 +a l + k+ ka ++lk+ + ++k+ q++ g+ +A ++L++ FUN_001477-T1 344 RASLLHREKQSAKAVEVLKNYAEChedsamNVKLTLVQLYLAQGNIGEACNTLRS 398 5556666677777777777653321122234444555666666666666666655 PP == domain 4 score: 1.8 bits; conditional E-value: 0.5 SRP_TPR_like 68 klkvlksqvlYflgy..ynkAyklLskvkkddeivvnlqA 105 l++++ v Y l++ ++A ++L k++k+d +v ++A FUN_001477-T1 448 VLSLMRENVSYKLQHgrAKEAVDMLEKLHKEDPTDVKTLA 487 4556667778877542256788999999999888888766 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.8 2.9e-09 2e-06 3 80 .. 25 102 .. 23 104 .. 0.95 2 ! 9.8 0.3 0.002 1.4 28 49 .. 114 135 .. 108 143 .. 0.83 3 ! 9.6 0.1 0.0024 1.6 5 59 .. 199 263 .. 195 275 .. 0.66 4 ? 0.0 0.2 2.2 1.5e+03 18 75 .. 297 357 .. 287 363 .. 0.53 5 ? 7.1 0.8 0.014 9.8 30 80 .. 345 397 .. 330 399 .. 0.82 6 ? 3.4 0.0 0.19 1.3e+02 2 31 .. 462 488 .. 461 498 .. 0.85 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 2.9e-09 ANAPC3 3 hqyknAiflaerllaaepespedayllAqclflngqykrAyellrkaklnekslgcryllAqcllkLkkykeAldaLe 80 ++++ A+ +a+++l+ +p++ e+ + cl +++ +++A++++++a ++ +++ + +A +l++L+k +eAl++L FUN_001477-T1 25 RNFEKALKIANKILQEKPDDKEAYHCKVICLIHQSCFREALDVINSAPKKGVDIELQFEKAYSLYRLNKTQEALNTLN 102 6899**********999******************************999**************************97 PP == domain 2 score: 9.8 bits; conditional E-value: 0.002 ANAPC3 28 llAqclflngqykrAyellrka 49 l Aq+l+++++y+++++l ++ FUN_001477-T1 114 LKAQVLYRLEDYHACLKLYKDL 135 67***************99987 PP == domain 3 score: 9.6 bits; conditional E-value: 0.0024 ANAPC3 5 yknAiflaerllaaepesped.........ayllAqclflngqykrAyellrka.klnekslgcr 59 +k A+ l+e+ l ++p+ e + lA+++ l+g+ ++A++l ++ k+++++l+ + FUN_001477-T1 199 LKKAEELCEKSLRDDPDIGEEefeaemgivRVQLAYVYQLQGKNDEAQKLYNQVlKSKPNDLALA 263 5667777777773222221112233344445668********************77777777544 PP == domain 4 score: 0.0 bits; conditional E-value: 2.2 ANAPC3 18 aepespedayll..AqclflngqykrAyellrka.klnekslgcryllAqcllkLkkykeA 75 + s + +++ ++ f+++q +++ +l+++ +++s + + A l++ k+ +A FUN_001477-T1 297 KLTASQQQTMTFnrCLLNFHTNQLEACRNLTSTLeAKYPESDFPCLMRASLLHREKQSAKA 357 5566666666663344446777777777777776555555554444444444444444444 PP == domain 5 score: 7.1 bits; conditional E-value: 0.014 ANAPC3 30 AqclflngqykrAyellrka.klneksl.gcryllAqcllkLkkykeAldaLe 80 A l +++q ++A+e+l++ ++ e s + l q +l+++++ eA ++L+ FUN_001477-T1 345 ASLLHREKQSAKAVEVLKNYaECHEDSAmNVKLTLVQLYLAQGNIGEACNTLR 397 77888999************88888888455555669999********99997 PP == domain 6 score: 3.4 bits; conditional E-value: 0.19 ANAPC3 2 nhqyknAiflaerllaaepespedayllAq 31 +++ k+A+ + e+l+ +e+p d+ +lAq FUN_001477-T1 462 HGRAKEAVDMLEKLH---KEDPTDVKTLAQ 488 678899999******...888888888887 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.2 0.11 76 15 34 .] 25 44 .. 23 44 .. 0.87 2 ? 7.3 0.2 0.012 8.1 2 26 .. 79 103 .. 78 110 .. 0.84 3 ? 7.3 0.3 0.012 8.4 7 30 .. 115 138 .. 113 142 .. 0.87 4 ! 8.3 0.3 0.0058 4 2 33 .. 177 208 .. 176 215 .. 0.76 5 ! 18.1 0.1 4.3e-06 0.003 6 34 .] 231 259 .. 228 259 .. 0.94 6 ? -0.0 0.0 2.7 1.9e+03 6 25 .. 343 362 .. 340 370 .. 0.70 7 ? 1.1 0.0 1.1 7.9e+02 9 24 .. 381 396 .. 381 403 .. 0.83 8 ? 1.0 0.0 1.2 8.6e+02 11 33 .. 416 438 .. 414 439 .. 0.70 9 ? 4.7 0.0 0.085 59 13 34 .] 461 482 .. 459 482 .. 0.92 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.11 TPR_2 15 gdyeeAleayekAleldPnn 34 ++e+Al+ +k l+ P++ FUN_001477-T1 25 RNFEKALKIANKILQEKPDD 44 6999*******999999986 PP == domain 2 score: 7.3 bits; conditional E-value: 0.012 TPR_2 2 ealynlGlayyklgdyeeAleayek 26 e+ ++ ++++y+l++ +eAl+ +++ FUN_001477-T1 79 ELQFEKAYSLYRLNKTQEALNTLNA 103 678999**************98776 PP == domain 3 score: 7.3 bits; conditional E-value: 0.012 TPR_2 7 lGlayyklgdyeeAleayekAlel 30 ++++y+l dy +l++y+ ++ FUN_001477-T1 115 KAQVLYRLEDYHACLKLYKDLIKN 138 699***************998875 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0058 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldPn 33 e++yn +++ + +d e A+e ++kA el+++ FUN_001477-T1 177 ELCYNSACLSLGENDIEAAEEKLKKAEELCEK 208 67788888888888888888888888887754 PP == domain 5 score: 18.1 bits; conditional E-value: 4.3e-06 TPR_2 6 nlGlayyklgdyeeAleayekAleldPnn 34 +l+++y +g+ +eA ++y+++l+ Pn+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVLKSKPND 259 69**********************99996 PP == domain 6 score: -0.0 bits; conditional E-value: 2.7 TPR_2 6 nlGlayyklgdyeeAleaye 25 +++ ++ + ++ ++A+e ++ FUN_001477-T1 343 MRASLLHREKQSAKAVEVLK 362 56777778888888877665 PP == domain 7 score: 1.1 bits; conditional E-value: 1.1 TPR_2 9 layyklgdyeeAleay 24 ++y+++g+ eA + + FUN_001477-T1 381 QLYLAQGNIGEACNTL 396 589*********8765 PP == domain 8 score: 1.0 bits; conditional E-value: 1.2 TPR_2 11 yyklgdyeeAleayekAleldPn 33 y + gd A++ +++A+e++ + FUN_001477-T1 416 YSHIGDVSAAVDILDEAVEHAQK 438 56667778888888888877655 PP == domain 9 score: 4.7 bits; conditional E-value: 0.085 TPR_2 13 klgdyeeAleayekAleldPnn 34 + g+ +eA++ +ek + dP++ FUN_001477-T1 461 QHGRAKEAVDMLEKLHKEDPTD 482 78999***************86 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 3.2 2.2e+03 15 32 .. 26 43 .. 21 44 .. 0.83 2 ! 8.3 0.2 0.0082 5.7 3 26 .. 81 104 .. 79 107 .. 0.88 3 ? 3.7 0.1 0.24 1.7e+02 7 29 .. 116 138 .. 114 141 .. 0.91 4 ! 16.2 0.2 2.5e-05 0.017 5 32 .. 231 258 .. 228 259 .. 0.91 5 ? -1.1 0.0 8 5.5e+03 15 33 .] 319 337 .. 312 337 .. 0.69 6 ? 2.4 0.0 0.61 4.2e+02 3 26 .. 342 364 .. 341 370 .. 0.74 7 ? 5.5 0.0 0.067 46 8 27 .. 381 400 .. 377 403 .. 0.88 8 ? 0.8 0.0 2.1 1.4e+03 9 28 .. 415 434 .. 412 438 .. 0.83 9 ? 7.3 0.0 0.018 12 9 32 .. 457 481 .. 456 482 .. 0.85 10 ? -0.6 0.0 5.6 3.9e+03 21 30 .. 484 493 .. 483 494 .. 0.88 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 3.2 TPR_6 15 dkdeAkaalqrlikkYPd 32 ++++A+++ ++++++ Pd FUN_001477-T1 26 NFEKALKIANKILQEKPD 43 899*********998665 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0082 TPR_6 3 llklalsylelgdkdeAkaalqrl 26 ++ a+s+++l++++eA+ +l+ + FUN_001477-T1 81 QFEKAYSLYRLNKTQEALNTLNAI 104 6778*****************976 PP == domain 3 score: 3.7 bits; conditional E-value: 0.24 TPR_6 7 alsylelgdkdeAkaalqrlikk 29 a+ +++l d+ +++++ lik+ FUN_001477-T1 116 AQVLYRLEDYHACLKLYKDLIKN 138 78899999*************98 PP == domain 4 score: 16.2 bits; conditional E-value: 2.5e-05 TPR_6 5 klalsylelgdkdeAkaalqrlikkYPd 32 +la+ y+ +g+ deA +++++++k+ P+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVLKSKPN 258 89*********************98776 PP == domain 5 score: -1.1 bits; conditional E-value: 8 TPR_6 15 dkdeAkaalqrlikkYPdS 33 + + + + l +kYP+S FUN_001477-T1 319 QLEACRNLTSTLEAKYPES 337 555566666677789**98 PP == domain 6 score: 2.4 bits; conditional E-value: 0.61 TPR_6 3 llklalsylelgdkdeAkaalqrl 26 l+++ l+++e + ++A+++l+ + FUN_001477-T1 342 LMRASLLHREK-QSAKAVEVLKNY 364 44555555555.********9976 PP == domain 7 score: 5.5 bits; conditional E-value: 0.067 TPR_6 8 lsylelgdkdeAkaalqrli 27 ++yl++g+ eA+ +l+++ FUN_001477-T1 381 QLYLAQGNIGEACNTLRSVK 400 6899*************986 PP == domain 8 score: 0.8 bits; conditional E-value: 2.1 TPR_6 9 sylelgdkdeAkaalqrlik 28 +y gd A+++l++ ++ FUN_001477-T1 415 LYSHIGDVSAAVDILDEAVE 434 466689*********99876 PP == domain 9 score: 7.3 bits; conditional E-value: 0.018 TPR_6 9 syle.lgdkdeAkaalqrlikkYPd 32 sy+ g+ +eA+++l++l k+ P+ FUN_001477-T1 457 SYKLqHGRAKEAVDMLEKLHKEDPT 481 6666469***************996 PP == domain 10 score: -0.6 bits; conditional E-value: 5.6 TPR_6 21 aalqrlikkY 30 ++l++lik Y FUN_001477-T1 484 KTLAQLIKAY 493 89******99 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.7 1.9e+03 25 37 .. 26 38 .. 24 49 .. 0.67 2 ! 7.8 0.1 0.0076 5.3 24 74 .. 59 107 .. 58 110 .. 0.90 3 ! 9.9 0.2 0.0017 1.2 9 42 .. 115 148 .. 112 163 .. 0.86 4 ! 18.5 1.1 3.5e-06 0.0024 13 73 .. 193 254 .. 185 258 .. 0.79 5 ! 16.8 0.1 1.2e-05 0.0081 5 31 .. 228 254 .. 224 268 .. 0.73 6 ? 3.4 0.1 0.17 1.2e+02 28 69 .. 356 397 .. 341 405 .. 0.67 7 ? 6.1 0.1 0.026 18 10 70 .. 413 474 .. 408 477 .. 0.56 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.7 TPR_12 25 llekalelaerll 37 ++ekal +a+++l FUN_001477-T1 26 NFEKALKIANKIL 38 4677777776654 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0076 TPR_12 24 ellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +++++al++++++ p++ ++ ++ + +++l++++eAl+ l+ e+ FUN_001477-T1 59 SCFREALDVINSA--PKKGVDIELQFEKAYSLYRLNKTQEALNTLNAIEEL 107 799*******999..99999***********************99977666 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0017 TPR_12 9 lAavlrrlgrydeAlellekalelaerllGpdhp 42 A+vl+rl++y+ +l+l++ + + +G++++ FUN_001477-T1 115 KAQVLYRLEDYHACLKLYKDLIKNSQDDYGDERE 148 699***************************9984 PP == domain 4 score: 18.5 bits; conditional E-value: 3.5e-06 TPR_12 13 lrrlgrydeAlellekalela.erllGpdhpltatalrnLgrlylalgdyeeAlelleqale 73 +++ +++ +A+el+ek+l+ ++ + +++ +L+ +y+++g+ +eA++l++q+l+ FUN_001477-T1 193 EAAEEKLKKAEELCEKSLRDDpDIGEEEFEAEMGIVRVQLAYVYQLQGKNDEAQKLYNQVLK 254 56778888899999999977733335556677899999999999999999999999999987 PP == domain 5 score: 16.8 bits; conditional E-value: 1.2e-05 TPR_12 5 alnnlAavlrrlgrydeAlellekale 31 + ++lA v++ +g+ deA++l++++l FUN_001477-T1 228 VRVQLAYVYQLQGKNDEAQKLYNQVLK 254 455678888888888888888877775 PP == domain 6 score: 3.4 bits; conditional E-value: 0.17 TPR_12 28 kalelaerllGpdhpltatalrnLgrlylalgdyeeAlelle 69 ka+e+ +++ + + + ++ +L +lyla+g+ eA + l+ FUN_001477-T1 356 KAVEVLKNYAECHEDSAMNVKLTLVQLYLAQGNIGEACNTLR 397 555555555555555677777777777777777777755554 PP == domain 7 score: 6.1 bits; conditional E-value: 0.026 TPR_12 10 AavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrl..y.lalgdyeeAlelleq 70 ++ + g+ A ++l++a+e a++ +d ++++l ++ + y l+ g+ +eA+++le+ FUN_001477-T1 413 VTLYSHIGDVSAAVDILDEAVEHAQKN--KDTMRQSEVLSLMRENvsYkLQHGRAKEAVDMLEK 474 456777777777777777777777776..33333333333332221231355777777777665 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 1.7 1.2e+03 16 27 .. 26 37 .. 23 44 .. 0.56 2 ? 3.7 0.4 0.18 1.3e+02 2 32 .. 79 109 .. 78 111 .. 0.86 3 ? 3.8 0.4 0.16 1.1e+02 6 33 .. 114 141 .. 113 142 .. 0.88 4 ! 9.0 1.2 0.0035 2.4 1 32 [. 176 207 .. 176 209 .. 0.93 5 ! 18.8 0.1 2.6e-06 0.0018 5 34 .] 230 259 .. 228 259 .. 0.94 6 ? 3.6 0.0 0.2 1.4e+02 4 25 .. 341 362 .. 340 366 .. 0.91 7 ? 4.5 0.0 0.1 71 6 30 .. 378 402 .. 375 405 .. 0.84 8 ? 3.0 0.0 0.29 2e+02 9 29 .. 414 434 .. 410 439 .. 0.87 9 ? -0.3 0.0 3.3 2.3e+03 15 32 .. 463 480 .. 458 482 .. 0.81 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.7 TPR_8 16 dyeeAkeyyeka 27 ++e+A ++ +k FUN_001477-T1 26 NFEKALKIANKI 37 455555555555 PP == domain 2 score: 3.7 bits; conditional E-value: 0.18 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 e+ + +++ + +l++ +eA ++++ el++ FUN_001477-T1 79 ELQFEKAYSLYRLNKTQEALNTLNAIEELKE 109 677899***************9998887765 PP == domain 3 score: 3.8 bits; conditional E-value: 0.16 TPR_8 6 nlGliylklgdyeeAkeyyekaleldpd 33 ++++++ +l+dy++ + y+ ++ ++d FUN_001477-T1 114 LKAQVLYRLEDYHACLKLYKDLIKNSQD 141 589*****************99987665 PP == domain 4 score: 9.0 bits; conditional E-value: 0.0035 TPR_8 1 aeayynlGliylklgdyeeAkeyyekaleldp 32 +e++yn +++ l +d+e+A+e ++ka el + FUN_001477-T1 176 YELCYNSACLSLGENDIEAAEEKLKKAEELCE 207 589************************99976 PP == domain 5 score: 18.8 bits; conditional E-value: 2.6e-06 TPR_8 5 ynlGliylklgdyeeAkeyyekaleldpdn 34 ++l+++y+ +g+ +eA++ y+++l+ +p++ FUN_001477-T1 230 VQLAYVYQLQGKNDEAQKLYNQVLKSKPND 259 68**************************96 PP == domain 6 score: 3.6 bits; conditional E-value: 0.2 TPR_8 4 yynlGliylklgdyeeAkeyye 25 ++++++++++ ++ ++A+e+++ FUN_001477-T1 341 CLMRASLLHREKQSAKAVEVLK 362 7899***************997 PP == domain 7 score: 4.5 bits; conditional E-value: 0.1 TPR_8 6 nlGliylklgdyeeAkeyyekalel 30 l ++yl +g++ eA ++++ + +l FUN_001477-T1 378 TLVQLYLAQGNIGEACNTLRSVKDL 402 5789************999977665 PP == domain 8 score: 3.0 bits; conditional E-value: 0.29 TPR_8 9 liylklgdyeeAkeyyekale 29 +y+ gd +A+ ++ +a+e FUN_001477-T1 414 TLYSHIGDVSAAVDILDEAVE 434 689****************98 PP == domain 9 score: -0.3 bits; conditional E-value: 3.3 TPR_8 15 gdyeeAkeyyekaleldp 32 g+ +eA+ +ek + dp FUN_001477-T1 463 GRAKEAVDMLEKLHKEDP 480 8999*******9877666 PP >> BTAD Bacterial transcriptional activator domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.8 0.00034 0.24 67 141 .. 80 154 .. 76 157 .. 0.92 2 ? 1.2 0.1 0.88 6.1e+02 19 117 .. 332 427 .. 318 451 .. 0.64 3 ! 21.5 0.1 4.8e-07 0.00033 59 110 .. 446 497 .. 420 502 .. 0.86 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00034 BTAD 67 alaeadlrlGraeeaiaelealvaehPlrErlhrqlmrAlyrsgrqaeALevYrrlrrvLaeeLgvepgpelral 141 +e+ +l r ++ + l+ l a + l+E ++ + lyr++ ++L+ Y++l + +++ g e +++l a+ FUN_001477-T1 80 LQFEKAYSLYRLNKTQEALNTLNAIEELKEHEKELKAQVLYRLEDYHACLKLYKDLIKNSQDDYGDERETNLAAV 154 567788888899999999**************************************************9999887 PP == domain 2 score: 1.2 bits; conditional E-value: 0.88 BTAD 19 agdpeeaaelleaAlalWrGpaladleagewleaererleelrlealealaeadlrlGraeeaiaelealvaehPlrErlhrqlmrAlyrsgrqae 114 a pe +l +A l r + a++ e+l+ +e e++++++ +l+++ l+ G++ ea ++l++ v+ ++ ++ +l++ +++ g ++ FUN_001477-T1 332 AKYPESDFPCLMRASLLHREKQSAKA--VEVLKNYAECHEDSAMNVKLTLVQLYLAQGNIGEACNTLRS-VKDLAYKPGVVSALVTLYSHIGDVSA 424 55566666666666666666666663..34777777777777888888888888888888888877765.44444555555555555555555555 PP BTAD 115 ALe 117 A + FUN_001477-T1 425 AVD 427 554 PP == domain 3 score: 21.5 bits; conditional E-value: 4.8e-07 BTAD 59 elrlealealaeadlrlGraeeaiaelealvaehPlrErlhrqlmrAlyrsg 110 + l+++++ + +l+ Gra+ea++ le+l++e+P++ ++ +ql++A+++++ FUN_001477-T1 446 SEVLSLMRENVSYKLQHGRAKEAVDMLEKLHKEDPTDVKTLAQLIKAYSCVN 497 456889999***************************************9987 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 7.7 5.3e+03 16 24 .. 83 91 .. 81 101 .. 0.52 2 ? 0.3 0.1 2 1.4e+03 13 32 .. 197 214 .. 193 217 .. 0.83 3 ! 13.8 0.1 9.5e-05 0.065 4 33 .. 231 258 .. 229 262 .. 0.81 4 ? -1.2 0.0 6.4 4.4e+03 19 33 .. 313 327 .. 312 330 .. 0.81 5 ? 3.9 0.0 0.15 1e+02 7 33 .. 381 407 .. 379 410 .. 0.90 6 ? 7.3 0.0 0.012 8.5 3 32 .. 410 439 .. 408 442 .. 0.84 7 ? 1.6 0.0 0.79 5.5e+02 13 35 .. 463 483 .. 460 484 .. 0.86 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 7.7 TPR_7 16 deAirlyer 24 ++A +ly+ FUN_001477-T1 83 EKAYSLYRL 91 555555543 PP == domain 2 score: 0.3 bits; conditional E-value: 2 TPR_7 13 GdydeAirlyerlLalakdp 32 ++ ++A++l+e+ +l+ dp FUN_001477-T1 197 EKLKKAEELCEK--SLRDDP 214 56789*******..999887 PP == domain 3 score: 13.8 bits; conditional E-value: 9.5e-05 TPR_7 4 aLariyrklGdydeAirlyerlLalakdpe 33 +La +y+ +G+ deA +ly ++L + +p+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVL--KSKPN 258 79*******************66..44443 PP == domain 4 score: -1.2 bits; conditional E-value: 6.4 TPR_7 19 irlyerlLalakdpe 33 +++++++L+++++++ FUN_001477-T1 313 LNFHTNQLEACRNLT 327 689999999999875 PP == domain 5 score: 3.9 bits; conditional E-value: 0.15 TPR_7 7 riyrklGdydeAirlyerlLalakdpe 33 ++y ++G+ eA+++++ + +la++p+ FUN_001477-T1 381 QLYLAQGNIGEACNTLRSVKDLAYKPG 407 79****************999999886 PP == domain 6 score: 7.3 bits; conditional E-value: 0.012 TPR_7 3 saLariyrklGdydeAirlyerlLalakdp 32 saL +y+ Gd A+++++++ + a++ FUN_001477-T1 410 SALVTLYSHIGDVSAAVDILDEAVEHAQKN 439 68889*****************77766655 PP == domain 7 score: 1.6 bits; conditional E-value: 0.79 TPR_7 13 GdydeAirlyerlLalakdpedr 35 G+ +eA++++e+ ++dp+d+ FUN_001477-T1 463 GRAKEAVDMLEK--LHKEDPTDV 483 66689*******..999999986 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.1 1.3 9.3e+02 236 273 .. 105 142 .. 88 168 .. 0.68 2 ! 8.7 0.1 0.0018 1.3 85 147 .. 188 251 .. 152 268 .. 0.72 3 ! 21.7 1.4 2.1e-07 0.00014 119 268 .. 335 477 .. 287 482 .. 0.75 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1.3 TPR_MalT 236 eyflerelrllarvllalgksdeAlrlleeLqelaeql 273 e ++e e++l a+vl l ++ + l+l ++L++++++ FUN_001477-T1 105 EELKEHEKELKAQVLYRLEDYHACLKLYKDLIKNSQDD 142 45677788888888888888888888888888888865 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0018 TPR_MalT 85 qqaellraqGqLhqAaetyqqalqlaqesklealp.lvgfllvgladLlyEwndLeeAeqhlqq 147 ++ +++ a+ +L++A+e++++ l+ ++ ++e+++ +g++ v+la ++ +++ +eA++ q FUN_001477-T1 188 GENDIEAAEEKLKKAEELCEKSLRDDPDIGEEEFEaEMGIVRVQLAYVYQLQGKNDEAQKLYNQ 251 4455788888888888888888888888888888624557777888888888888888776555 PP == domain 3 score: 21.7 bits; conditional E-value: 2.1e-07 TPR_MalT 119 plvgfllvgladLlyEwndLeeAeqhlqqgiqlgrqlepaaaleayvllarvalaqGeleeAetllqraerlaresrfhvdwlanaeavrvrlwla 214 p + f++ +a Ll+ + +A + l+ + ++ a++ +++l+++ laqG++ eA +l+ + la + ++++ v l+ + FUN_001477-T1 335 PESDFPCLMRASLLHREKQSAKAVEVLKNY----AECHEDSAMNVKLTLVQLYLAQGNIGEACNTLRSVKDLAYKPGVVSA--------LVTLYSH 418 555555555555555555555555544433....445678899999**************************998888422........2445689 PP TPR_MalT 215 rgdlraaeewlraaeq.pssaseyflerelrllarvllal....gksdeAlrlleeLqe 268 gd++aa++ l +a + +++ ++ ++++e+ l+r ++ g+ +eA le+L++ FUN_001477-T1 419 IGDVSAAVDILDEAVEhAQKNKDTMRQSEVLSLMRENVSYklqhGRAKEAVDMLEKLHK 477 9********99999761455567999999999999654433333999999999999987 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 1.6 0.082 57 56 119 .. 77 134 .. 22 155 .. 0.67 2 ! 10.9 0.2 0.00068 0.47 17 84 .. 186 253 .. 174 259 .. 0.85 3 ! 9.9 0.3 0.0013 0.92 63 121 .. 344 400 .. 281 405 .. 0.85 4 ! 14.5 3.2 5.3e-05 0.037 11 130 .. 342 485 .. 341 494 .. 0.66 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.082 ARM_TT21 56 kvsvylelidvlsklkkveeAkkllqeaieefkgtpeevrillanaelalargdvdkAlelLkk 119 +++++e + l +l+k++eA ++l+ aiee+k+ ++e +a+++ +d++++l+l k FUN_001477-T1 77 DIELQFEKAYSLYRLNKTQEALNTLN-AIEELKEHEKEL-----KAQVLYRLEDYHACLKLYKD 134 56677777777778888888888875.677777766664.....55555666666666665554 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00068 ARM_TT21 17 lkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeai 84 e+++e A + Lk+A +l +k+ + + +e e + v ++l+ v++ ++k +eA+kl ++++ FUN_001477-T1 186 SLGENDIEAAEEKLKKAEELCEKSLRDDPDIGEEEFEAEMGIVRVQLAYVYQLQGKNDEAQKLYNQVL 253 556899**************99887777666667778888999********************99876 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0013 ARM_TT21 63 lidvlsklkkveeAkkllqeaieefkgtpeevrillanaelalargdvdkAlelLkkik 121 +++l++ k++++A ++l++ e ++++ +v+++l ++l+la+g++ +A ++L+++k FUN_001477-T1 344 RASLLHREKQSAKAVEVLKNYAECHEDSAMNVKLTL--VQLYLAQGNIGEACNTLRSVK 400 466777888888888888888888877776666666..579999************997 PP == domain 4 score: 14.5 bits; conditional E-value: 5.3e-05 ARM_TT21 11 likakvlkkegkleeAlktLktAlklpgkkkskekkke..............kessesdkvs.......vylelidvlsklkkveeAkkllqeai. 84 l++a++l++e++ +A+++Lk+ + + + + k + +++ + + v l+ ++s++++v+ A +l+ea+ FUN_001477-T1 342 LMRASLLHREKQSAKAVEVLKNYAECHEDSAMNVKLTLvqlylaqgnigeacNTLRSV---KdlaykpgVVSALVTLYSHIGDVSAAVDILDEAVe 434 7889999999999999999999999876544333222111122111111111112222...13334555999**********************94 PP ARM_TT21 85 ..eefkgtpeevr...illanaelalargdvdkAlelLkkikpdspyylqA 130 ++ k+t +++ ++ n++ l++g ++A+++L+k ++++p+ ++ FUN_001477-T1 435 haQKNKDTMRQSEvlsLMRENVSYKLQHGRAKEAVDMLEKLHKEDPTDVKT 485 44344455555441113445788899******************9998875 PP >> ARM_TT21_N Tetratricopeptide repeat protein 21 N-terminal ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 1.5 1e+03 179 205 .. 22 48 .. 13 59 .. 0.67 2 ! 19.4 3.1 1.4e-06 0.00096 5 200 .. 56 258 .. 52 265 .. 0.76 3 ! 11.4 3.7 0.00039 0.27 34 194 .. 233 399 .. 227 417 .. 0.75 4 ? 3.2 0.1 0.13 88 109 166 .. 415 479 .. 406 493 .. 0.41 5 ? 3.1 0.1 0.13 93 38 72 .. 460 494 .. 457 504 .. 0.86 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 1.5 ARM_TT21_N 179 ekrknysealevlnqlivaypkflpal 205 k +n+++al+++n+++ + p+ a+ FUN_001477-T1 22 GKDRNFEKALKIANKILQEKPDDKEAY 48 566777777777777777766644444 PP == domain 2 score: 19.4 bits; conditional E-value: 1.4e-06 ARM_TT21_N 5 lrekyyrhaqtvceealkksndpvlkfykalglllegrvqeAireLeslke....krdvsLaallaliyahkkcknvDreavaeleaklkeeekkk 96 +++ ++r+a++v+++a kk d +l+f ka++l+ +++qeA++ L+ ++e +++++ +l+ l +h +c ++ ++ +++ + +e++++ FUN_001477-T1 56 IHQSCFREALDVINSAPKKGVDIELQFEKAYSLYRLNKTQEALNTLNAIEElkehEKELKAQVLYRLEDYH-ACLKLYKDLIKNSQDDYGDERETN 150 678899**************************************998775422124555555555555555.677888999***999999876542 PP ARM_TT21_N 97 aaeeaslylaalfllllgkydkAreyidralklsssssaealilkGWieltsgke.qkkaqelfeea......geqknpdallG.....kakylek 180 + ++a+ + k+d+ d l + +a + G ++++++e kka+el e++ +++++ +a +G a +++ FUN_001477-T1 151 ----LAAVIAGAAQWKGMKMDELGLREDTYE-L---CYNSACLSLGENDIEAAEEkLKKAEELCEKSlrddpdIGEEEFEAEMGivrvqLAYVYQL 238 ....344568888888888777665555443.3...355678889*****88665499999*****966665555678999999554444457999 PP ARM_TT21_N 181 rknysealevlnqlivaypk 200 +++ +ea+++ nq++ + p+ FUN_001477-T1 239 QGKNDEAQKLYNQVLKSKPN 258 **************999886 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00039 ARM_TT21_N 34 alglllegrvqeAireLeslkek..rdvsLaalla..liyahkkcknvDre.avaeleaklkeeekkkaaeeaslylaalfllllgkydkAreyid 124 a+ + l+g+ eA + +++ + d++Laa+++ i+ k ++ D + v++ a + +++++++ + +l+ +++++++ r + + FUN_001477-T1 233 AYVYQLQGKNDEAQKLYNQVLKSkpNDLALAAVASnnVITLNKDRDVFDSKkKVKATTADELAHKLTASQQQTMTFNRCLLNFHTNQLEACRNLTS 328 89999************9986552468999988873356777888888854156666665445556677777888888899999999999999998 PP ARM_TT21_N 125 ralklsssssaealilkGWieltsgkeqkkaqelfeea...geqknpdallGkakylekrknysealevlnql 194 + + ++++ +l+ l+++k++ ka e++++ +e++ ++ l ++++ ++n+ ea+++l ++ FUN_001477-T1 329 TLEAKYP--ESDFPCLMRASLLHREKQSAKAVEVLKNYaecHEDSAMNVKLTLVQLYLAQGNIGEACNTLRSV 399 8876554..5799**************9988877666511155666778899999999999999999998765 PP == domain 4 score: 3.2 bits; conditional E-value: 0.13 ARM_TT21_N 109 fllllgkydkAreyidralklsssssaealilkGWieltsgke........qkkaqelfeeageqk 166 ++ ++g++ A +++d+a++ +++ +++ + + l++++ k+a +++e+ ++++ FUN_001477-T1 415 LYSHIGDVSAAVDILDEAVEHAQK-NKDTMRQSEVLSLMRENVsyklqhgrAKEAVDMLEKLHKED 479 555666666666666666554433.23333222222222222211122222333334444443333 PP == domain 5 score: 3.1 bits; conditional E-value: 0.13 ARM_TT21_N 38 llegrvqeAireLeslkekrdvsLaallaliyahk 72 l+ gr +eA+ Le+l ++ + + +l+ li a++ FUN_001477-T1 460 LQHGRAKEAVDMLEKLHKEDPTDVKTLAQLIKAYS 494 568999**********9999999999999999986 PP >> ARM_TT21_5th TT21 fifth ARM repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.0 9.4e-05 0.065 38 100 .. 11 73 .. 3 77 .. 0.92 2 ! 8.7 0.1 0.0042 2.9 17 96 .. 27 102 .. 25 114 .. 0.53 3 ? 2.3 0.0 0.42 2.9e+02 6 35 .. 114 143 .. 109 145 .. 0.87 4 ? 6.2 0.5 0.026 18 15 88 .. 240 320 .. 229 334 .. 0.58 5 ? 1.2 0.0 0.91 6.3e+02 5 63 .. 342 401 .. 338 410 .. 0.79 6 ? 2.6 0.0 0.34 2.4e+02 15 43 .. 463 491 .. 447 496 .. 0.84 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 9.4e-05 ARM_TT21_5th 38 LarliellrrsGkleeaekflekaekassraklepgfnyckglyewytgklneaLrefnkaRk 100 + +l + l r Gk +++ek+l+ a+k ++++ ++ + +ck ++ ++ +eaL +n+a k FUN_001477-T1 11 IPQLFTELDRFGKDRNFEKALKIANKILQEKPDDKEAYHCKVICLIHQSCFREALDVINSAPK 73 568888899**************************************************9965 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0042 ARM_TT21_5th 17 lekAifhfqqlLekkpdnyeaLarliellrrsGkleeaekflekaekassraklepgfnyckglyewytgklneaLrefn 96 +ekA++ +++L++kpd+ ea + + l ++ +ea ++++a k+ + ++++ k+ +k++eaL+++n FUN_001477-T1 27 FEKALKIANKILQEKPDDKEAYHCKVICLIHQSCFREALDVINSAPKKG----VDIELQFEKAYSLYRLNKTQEALNTLN 102 5555555566666666655555544444455545555555555555432....334444444444445555555555555 PP == domain 3 score: 2.3 bits; conditional E-value: 0.42 ARM_TT21_5th 6 mmAdlafrkqdlekAifhfqqlLekkpdny 35 + A++++r +d+ + ++ +++l++++ d+y FUN_001477-T1 114 LKAQVLYRLEDYHACLKLYKDLIKNSQDDY 143 56999******************9998877 PP == domain 4 score: 6.2 bits; conditional E-value: 0.026 ARM_TT21_5th 15 qdlekAifhfqqlLekkpdnye....aLarliellrrsGkleeaekflekaekassr...aklepgfnyckglyewytgkl 88 + ++A++ ++q+L++kp++ + a +++i+l + + ++ +k+ ++ ++++++ a++++ +++ + l++ +t++l FUN_001477-T1 240 GKNDEAQKLYNQVLKSKPNDLAlaavASNNVITLNKDRDVFDSKKKVKATTADELAHkltASQQQTMTFNRCLLNFHTNQL 320 57899*************987522112345666666665544433332222222221111344445555555666666555 PP == domain 5 score: 1.2 bits; conditional E-value: 0.91 ARM_TT21_5th 5 vmmAdlafrkqdlekAifhfqqlLekkpdn.yeaLarliellrrsGkleeaekflekaek 63 +m A l+ r ++ kA+ +++ e + d+ ++ l++l +G++ ea + l+++++ FUN_001477-T1 342 LMRASLLHREKQSAKAVEVLKNYAECHEDSaMNVKLTLVQLYLAQGNIGEACNTLRSVKD 401 688999999999999999999988876654156667899999999999998888877765 PP == domain 6 score: 2.6 bits; conditional E-value: 0.34 ARM_TT21_5th 15 qdlekAifhfqqlLekkpdnyeaLarlie 43 ++A+ +++l ++ p++ ++La+li+ FUN_001477-T1 463 GRAKEAVDMLEKLHKEDPTDVKTLAQLIK 491 456899999******************98 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.42 2.9e+02 9 26 .. 20 37 .. 18 41 .. 0.80 2 ? 0.0 0.0 2.7 1.9e+03 13 31 .] 58 76 .. 53 76 .. 0.80 3 ? -1.7 0.0 9.9 6.8e+03 17 24 .. 83 90 .. 81 106 .. 0.62 4 ? 0.5 0.0 2 1.3e+03 10 29 .. 119 138 .. 117 139 .. 0.83 5 ? -1.7 0.2 9.6 6.6e+03 14 25 .. 197 208 .. 194 212 .. 0.80 6 ? 1.1 0.0 1.2 8.5e+02 13 28 .. 239 254 .. 234 256 .. 0.84 7 ? -0.4 0.0 3.6 2.5e+03 5 25 .. 378 398 .. 377 402 .. 0.83 8 ? 6.5 0.0 0.023 16 4 28 .. 410 434 .. 408 435 .. 0.89 9 ? 4.7 0.1 0.09 62 12 29 .. 461 478 .. 460 479 .. 0.89 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.42 PPR 9 gycknGkleeAlelfkeM 26 ++k +++e+Al++ +++ FUN_001477-T1 20 RFGKDRNFEKALKIANKI 37 689*********986665 PP == domain 2 score: 0.0 bits; conditional E-value: 2.7 PPR 13 nGkleeAlelfkeMkekGi 31 +++eAl++++ +kG+ FUN_001477-T1 58 QSCFREALDVINSAPKKGV 76 56899*****999888886 PP == domain 3 score: -1.7 bits; conditional E-value: 9.9 PPR 17 eeAlelfk 24 e+A +l++ FUN_001477-T1 83 EKAYSLYR 90 56666554 PP == domain 4 score: 0.5 bits; conditional E-value: 2 PPR 10 ycknGkleeAlelfkeMkek 29 + + +++ +l+l+k+++++ FUN_001477-T1 119 LYRLEDYHACLKLYKDLIKN 138 567889999******99886 PP == domain 5 score: -1.7 bits; conditional E-value: 9.6 PPR 14 GkleeAlelfke 25 kl++A+el ++ FUN_001477-T1 197 EKLKKAEELCEK 208 6899****9886 PP == domain 6 score: 1.1 bits; conditional E-value: 1.2 PPR 13 nGkleeAlelfkeMke 28 Gk +eA +l+++ ++ FUN_001477-T1 239 QGKNDEAQKLYNQVLK 254 6999*******98776 PP == domain 7 score: -0.4 bits; conditional E-value: 3.6 PPR 5 slIsgycknGkleeAlelfke 25 +l++ y G++ eA ++ FUN_001477-T1 378 TLVQLYLAQGNIGEACNTLRS 398 79999**********887765 PP == domain 8 score: 6.5 bits; conditional E-value: 0.023 PPR 4 nslIsgycknGkleeAlelfkeMke 28 ++l+ y++ G+++ A+++++e +e FUN_001477-T1 410 SALVTLYSHIGDVSAAVDILDEAVE 434 7899*****************9665 PP == domain 9 score: 4.7 bits; conditional E-value: 0.09 PPR 12 knGkleeAlelfkeMkek 29 ++G+ +eA+++++++ ++ FUN_001477-T1 461 QHGRAKEAVDMLEKLHKE 478 79***********99875 PP >> TPR_21 Tetratricopeptide repeat-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.5 2 1.4e+03 126 169 .. 91 132 .. 81 165 .. 0.68 2 ? 4.3 0.7 0.058 40 112 139 .. 225 252 .. 181 261 .. 0.64 3 ! 26.3 0.3 1.1e-08 7.3e-06 31 188 .. 296 460 .. 293 463 .. 0.81 4 ? 0.4 0.2 0.94 6.5e+02 35 92 .. 445 501 .. 435 503 .. 0.67 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 2 TPR_21 126 ekkydeALktLeakkdeafaalvaelkGDilvaqgkldeAraAY 169 +k++eAL+tL+a + + + + +elk +l++ ++ + + Y FUN_001477-T1 91 LNKTQEALNTLNAIE--ELKEHEKELKAQVLYRLEDYHACLKLY 132 466777777777664..456666666666666666555555544 PP == domain 2 score: 4.3 bits; conditional E-value: 0.058 TPR_21 112 kavarlrLarvllaekkydeALktLeak 139 ++r++La v ++k deA k+ +++ FUN_001477-T1 225 MGIVRVQLAYVYQLQGKNDEAQKLYNQV 252 4578888888888888888887766554 PP == domain 3 score: 26.3 bits; conditional E-value: 1.1e-08 TPR_21 31 yqekqaeeAsalYqqlleaveakdaakaeaaaaelkdeyggtaYaalaaLllAkaavekgdlaaAkaqLewvadkakdeelkavarlrLarvllae 126 ++ + +++ ++++ l ++++++ ++ ++ ++ l+++y+++ ++ L+ A +++ a+A + L++ a+ +d++++ ++l L ++ la+ FUN_001477-T1 296 HKLTASQQQTMTFNRCLLNFHTNQLEACRNLTSTLEAKYPES---DFPCLMRASLLHREKQSAKAVEVLKNYAECHEDSAMN--VKLTLVQLYLAQ 386 6677888999999999999**********************9...8899***************************999877..8*********** PP TPR_21 127 kkydeALktLeakkdeafaalvaelk.......GDilvaqgkldeAraAYqaAlaaleeee.....rellqlKl 188 +++ eA +tL ++kd a++ v GD+ +a + ldeA + q+ +++ ++e re +++Kl FUN_001477-T1 387 GNIGEACNTLRSVKDLAYKPGVVSALvtlyshiGDVSAAVDILDEAVEHAQKNKDTMRQSEvlslmRENVSYKL 460 ******************97655443011112277777777777776666666666666655555555555555 PP == domain 4 score: 0.4 bits; conditional E-value: 0.94 TPR_21 35 qaeeAsalYqqlleaveakdaakaeaaaaelkdeyggtaYaalaaLllAkaavekgdl 92 q+e s + +++ +++++ a++a ++ ++l +e + la+L++A + v+ +++ FUN_001477-T1 445 QSEVLSLMRENVSYKLQHGRAKEAVDMLEKLHKEDPTD-VKTLAQLIKAYSCVNPKKA 501 44444555566666777777788888888887776655.7888999988887776665 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.0032 2.2 9 50 .. 25 66 .. 21 70 .. 0.94 2 ? 1.9 0.0 0.49 3.4e+02 28 59 .. 77 108 .. 75 123 .. 0.83 3 ? -1.7 0.0 6.4 4.4e+03 35 50 .. 115 130 .. 110 142 .. 0.77 4 ? -2.0 0.0 7.8 5.4e+03 38 63 .. 185 214 .. 174 218 .. 0.61 5 ? -1.5 0.0 5.3 3.7e+03 35 58 .. 344 367 .. 343 373 .. 0.75 6 ? 5.0 0.0 0.05 34 38 64 .. 415 441 .. 414 456 .. 0.82 7 ? -0.9 0.0 3.4 2.4e+03 11 36 .. 462 487 .. 454 491 .. 0.63 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0032 TPR_9 9 edleralavverllllaPddpeerrdrGllyaqlgcleaAla 50 +++e+al++ + +l+ +Pdd e + + +++ ++ c+ +Al+ FUN_001477-T1 25 RNFEKALKIANKILQEKPDDKEAYHCKVICLIHQSCFREALD 66 799***********************************9986 PP == domain 2 score: 1.9 bits; conditional E-value: 0.49 TPR_9 28 dpeerrdrGllyaqlgcleaAladLeaylala 59 d+e+ ++++ +++l+ +++Al L+a +l+ FUN_001477-T1 77 DIELQFEKAYSLYRLNKTQEALNTLNAIEELK 108 57788899999************999865555 PP == domain 3 score: -1.7 bits; conditional E-value: 6.4 TPR_9 35 rGllyaqlgcleaAla 50 +++++++l++++a l+ FUN_001477-T1 115 KAQVLYRLEDYHACLK 130 6889999999998665 PP == domain 4 score: -2.0 bits; conditional E-value: 7.8 TPR_9 38 lyaqlgcleaAladLeaylalap....dap 63 l +++eaA + L+++ +l++ d+p FUN_001477-T1 185 LSLGENDIEAAEEKLKKAEELCEkslrDDP 214 555556777777777777666665554444 PP == domain 5 score: -1.5 bits; conditional E-value: 5.3 TPR_9 35 rGllyaqlgcleaAladLeaylal 58 r++l+++ + ++A++ L+ y++ FUN_001477-T1 344 RASLLHREKQSAKAVEVLKNYAEC 367 778888888888888888888865 PP == domain 6 score: 5.0 bits; conditional E-value: 0.05 TPR_9 38 lyaqlgcleaAladLeaylalapdapd 64 ly + g+++aA++ L+ ++++a ++ d FUN_001477-T1 415 LYSHIGDVSAAVDILDEAVEHAQKNKD 441 799*****************9986555 PP == domain 7 score: -0.9 bits; conditional E-value: 3.4 TPR_9 11 leralavverllllaPddpeerrdrG 36 + ra ++v++l l+ +dp+++ + FUN_001477-T1 462 HGRAKEAVDMLEKLHKEDPTDVKTLA 487 44555666666666666666655555 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.88 6e+02 9 34 .. 23 48 .. 15 75 .. 0.68 2 ? 4.0 0.0 0.14 99 2 22 .. 83 103 .. 79 112 .. 0.72 3 ? 2.9 0.1 0.32 2.2e+02 3 28 .. 115 140 .. 113 163 .. 0.82 4 ? -0.2 0.0 2.9 2e+03 40 62 .. 192 214 .. 185 215 .. 0.77 5 ! 9.1 0.1 0.0037 2.6 3 30 .. 232 259 .. 230 268 .. 0.82 6 ? -1.3 0.0 6.6 4.5e+03 36 61 .. 343 368 .. 342 372 .. 0.72 7 ? 1.9 0.0 0.65 4.5e+02 2 23 .. 378 399 .. 377 441 .. 0.56 8 ? -0.8 0.0 4.6 3.2e+03 8 62 .. 460 480 .. 456 493 .. 0.65 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.88 TPR_16 9 aagdyddAaaaleaalrrnPeaaaAl 34 + ++++ A++ + l P++ +A+ FUN_001477-T1 23 KDRNFEKALKIANKILQEKPDDKEAY 48 56777777777777777777777776 PP == domain 2 score: 4.0 bits; conditional E-value: 0.14 TPR_16 2 alaraalaagdyddAaaalea 22 ++a +++++++ ++A++ l a FUN_001477-T1 83 EKAYSLYRLNKTQEALNTLNA 103 567777777777777777765 PP == domain 3 score: 2.9 bits; conditional E-value: 0.32 TPR_16 3 laraalaagdyddAaaaleaalrrnP 28 +a+ +++++dy + +++++ ++++ FUN_001477-T1 115 KAQVLYRLEDYHACLKLYKDLIKNSQ 140 7999****************999873 PP == domain 4 score: -0.2 bits; conditional E-value: 2.9 TPR_16 40 allrqgrlaeAaaayraalraap 62 ++++ +l +A++++++ lr +p FUN_001477-T1 192 IEAAEEKLKKAEELCEKSLRDDP 214 56677788888888888888887 PP == domain 5 score: 9.1 bits; conditional E-value: 0.0037 TPR_16 3 laraalaagdyddAaaaleaalrrnPea 30 la + +g++d+A++++ ++l++ P + FUN_001477-T1 232 LAYVYQLQGKNDEAQKLYNQVLKSKPND 259 67777779****************9854 PP == domain 6 score: -1.3 bits; conditional E-value: 6.6 TPR_16 36 glGlallrqgrlaeAaaayraalraa 61 ++ +l+r + a+A+++++ ++++ FUN_001477-T1 343 MRASLLHREKQSAKAVEVLKNYAECH 368 57888888888888888887776554 PP == domain 7 score: 1.9 bits; conditional E-value: 0.65 TPR_16 2 alaraalaagdyddAaaaleaa 23 +l++++la+g+ +A + l+ + FUN_001477-T1 378 TLVQLYLAQGNIGEACNTLRSV 399 5677788888877776666544 PP == domain 8 score: -0.8 bits; conditional E-value: 4.6 TPR_16 8 laagdyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraalraap 62 l++g+ +A+ le + + + p FUN_001477-T1 460 LQHGRAKEAVDMLEKLHKED----------------------------------P 480 55566666666655554444..................................3 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.044 30 4 21 .. 229 246 .. 227 251 .. 0.89 2 ! 9.6 0.0 0.0034 2.3 5 25 .. 377 397 .. 374 398 .. 0.90 3 ? 0.5 0.0 2.9 2e+03 15 25 .. 463 473 .. 460 474 .. 0.89 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.044 TPR_4 4 llaLArallalGdldeAr 21 ++ LA +++++G deA+ FUN_001477-T1 229 RVQLAYVYQLQGKNDEAQ 246 789**************7 PP == domain 2 score: 9.6 bits; conditional E-value: 0.0034 TPR_4 5 laLArallalGdldeAralle 25 l L +++la+G+ eA+ +l+ FUN_001477-T1 377 LTLVQLYLAQGNIGEACNTLR 397 56899************9998 PP == domain 3 score: 0.5 bits; conditional E-value: 2.9 TPR_4 15 GdldeAralle 25 G++ eA ++le FUN_001477-T1 463 GRAKEAVDMLE 473 9*********9 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.18 1.3e+02 15 34 .] 25 44 .. 21 44 .. 0.84 2 ? 2.9 0.2 0.22 1.5e+02 5 22 .. 82 99 .. 78 110 .. 0.83 3 ? 3.5 0.4 0.15 1e+02 7 25 .. 115 133 .. 114 141 .. 0.89 4 ? 4.0 0.2 0.097 67 14 28 .. 196 210 .. 177 215 .. 0.78 5 ! 18.4 0.2 2.8e-06 0.0019 6 34 .] 231 259 .. 228 259 .. 0.94 6 ? -1.9 0.1 7.5 5.2e+03 10 20 .. 382 392 .. 381 392 .. 0.84 7 ? 0.8 0.0 1 7e+02 10 34 .] 415 439 .. 414 439 .. 0.79 8 ? -1.4 0.0 5.1 3.5e+03 15 34 .] 463 482 .. 460 482 .. 0.82 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.18 TPR_1 15 gkydeAleyyekALelnPnn 34 ++++Al+ +k L+ P++ FUN_001477-T1 25 RNFEKALKIANKILQEKPDD 44 68999999999999999986 PP == domain 2 score: 2.9 bits; conditional E-value: 0.22 TPR_1 5 ynlGnayfklgkydeAle 22 + +++ +++l+k +eAl FUN_001477-T1 82 FEKAYSLYRLNKTQEALN 99 67899***********96 PP == domain 3 score: 3.5 bits; conditional E-value: 0.15 TPR_1 7 lGnayfklgkydeAleyye 25 +++++++l++y +l+ y+ FUN_001477-T1 115 KAQVLYRLEDYHACLKLYK 133 689999*******999997 PP == domain 4 score: 4.0 bits; conditional E-value: 0.097 TPR_1 14 lgkydeAleyyekAL 28 +k+++A+e +ek L FUN_001477-T1 196 EEKLKKAEELCEKSL 210 467788888888877 PP == domain 5 score: 18.4 bits; conditional E-value: 2.8e-06 TPR_1 6 nlGnayfklgkydeAleyyekALelnPnn 34 +l+++y+ +gk deA + y+++L+ Pn+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVLKSKPND 259 69**********************99996 PP == domain 6 score: -1.9 bits; conditional E-value: 7.5 TPR_1 10 ayfklgkydeA 20 +y+++g+ eA FUN_001477-T1 382 LYLAQGNIGEA 392 7999*999887 PP == domain 7 score: 0.8 bits; conditional E-value: 1 TPR_1 10 ayfklgkydeAleyyekALelnPnn 34 +y + g+ A++ ++A+e+ +n FUN_001477-T1 415 LYSHIGDVSAAVDILDEAVEHAQKN 439 5888888899999999998887765 PP == domain 8 score: -1.4 bits; conditional E-value: 5.1 TPR_1 15 gkydeAleyyekALelnPnn 34 g+ +eA++ ek + +P++ FUN_001477-T1 463 GRAKEAVDMLEKLHKEDPTD 482 66689******999999985 PP >> TPR_24 Fungal tetratrico peptide repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.1 0.028 20 43 131 .. 52 133 .. 25 135 .. 0.71 2 ! 7.8 0.0 0.0063 4.3 41 105 .. 378 443 .. 350 458 .. 0.86 3 ! 11.5 0.2 0.00044 0.3 41 118 .. 411 494 .. 409 501 .. 0.84 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.028 TPR_24 43 ieafaragdlkeAlrvleimrkagi..eptkettrpifealkkdpeaidsalealeelkkegkkvdiaalnvviealvslgdlqrAlglYk 131 + + ++++ ++eAl v++ k+g+ e + e++ +++++ k++ + ++l+a+eelk+++k+ ++ +l +l+d+++ l+lYk FUN_001477-T1 52 VICLIHQSCFREALDVINSAPKKGVdiELQFEKAYSLYRLNKTQ--EALNTLNAIEELKEHEKELKAQ-------VLYRLEDYHACLKLYK 133 447888899999********999982245567788888755544..44689999*****999876654.......4455555555555555 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0063 TPR_24 41 alieafaragdlkeAlrvleimrkagieptket.trpifealkkdpeaidsalealeelkkegkkv 105 l++ ++ +g++ eA ++l+ ++ +p + ++++++ + ++a+d ea+e+++k++ ++ FUN_001477-T1 378 TLVQLYLAQGNIGEACNTLRSVKDLAYKPGVVSaLVTLYSHIGDVSAAVDILDEAVEHAQKNKDTM 443 59999************************9877256899999999999999999999999887665 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00044 TPR_24 41 alieafaragdlkeAlrvle.imrkagieptkettrpifealkkd......peaidsalealeelkkegkkvdiaalnvviealv 118 al+ + + gd+++A+ +l+ ++a+ + ++ + ++++++++ + ++a+++le+l+ke + d+++l+ +i+a+ FUN_001477-T1 411 ALVTLYSHIGDVSAAVDILDeAVEHAQKNKDTMRQSEVLSLMRENvsyklqHGRAKEAVDMLEKLHKE-DPTDVKTLAQLIKAYS 494 8999999***********9735666666667777788889999888888877789************9.88***********985 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.015 10 3 33 .. 35 65 .. 33 66 .. 0.91 2 ? -0.0 0.1 3 2.1e+03 14 33 .. 79 98 .. 77 99 .. 0.84 3 ? -0.2 0.0 3.4 2.4e+03 1 11 [. 205 215 .. 205 218 .. 0.89 4 ? 6.9 0.0 0.019 13 18 34 .] 231 247 .. 227 247 .. 0.90 5 ? -1.5 0.1 8.9 6.2e+03 1 12 [. 248 259 .. 248 262 .. 0.90 6 ? 0.5 0.0 2 1.4e+03 17 33 .. 342 358 .. 332 359 .. 0.83 7 ? -1.3 0.0 7.8 5.4e+03 21 33 .. 381 393 .. 378 394 .. 0.84 8 ? -1.3 0.0 7.8 5.4e+03 7 19 .. 477 489 .. 472 489 .. 0.82 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.015 TPR_17 3 lkaleldPnnadayynLArlllnnGqleeAl 33 +k l+ P++ +ay+++ ++l ++ + eAl FUN_001477-T1 35 NKILQEKPDDKEAYHCKVICLIHQSCFREAL 65 6899999****************99998886 PP == domain 2 score: -0.0 bits; conditional E-value: 3 TPR_17 14 dayynLArlllnnGqleeAl 33 ++ + +A+ l ++++++eAl FUN_001477-T1 79 ELQFEKAYSLYRLNKTQEAL 98 667889999999**999997 PP == domain 3 score: -0.2 bits; conditional E-value: 3.4 TPR_17 1 lylkaleldPn 11 l++k+l+ dP+ FUN_001477-T1 205 LCEKSLRDDPD 215 79********8 PP == domain 4 score: 6.9 bits; conditional E-value: 0.019 TPR_17 18 nLArlllnnGqleeAlq 34 +LA++++ +G+ +eA++ FUN_001477-T1 231 QLAYVYQLQGKNDEAQK 247 8**************95 PP == domain 5 score: -1.5 bits; conditional E-value: 8.9 TPR_17 1 lylkaleldPnn 12 ly+++l+ Pn+ FUN_001477-T1 248 LYNQVLKSKPND 259 79********98 PP == domain 6 score: 0.5 bits; conditional E-value: 2 TPR_17 17 ynLArlllnnGqleeAl 33 ++A ll++ +q+++A+ FUN_001477-T1 342 LMRASLLHREKQSAKAV 358 58999**********97 PP == domain 7 score: -1.3 bits; conditional E-value: 7.8 TPR_17 21 rlllnnGqleeAl 33 +l+l +G+ eA+ FUN_001477-T1 381 QLYLAQGNIGEAC 393 799****999985 PP == domain 8 score: -1.3 bits; conditional E-value: 7.8 TPR_17 7 eldPnnadayynL 19 + dP++++ + +L FUN_001477-T1 477 KEDPTDVKTLAQL 489 579****999876 PP >> TPR-S Tetratricopeptide Repeats-Sensor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.8 0.0044 3 2 47 .. 61 107 .. 26 117 .. 0.83 2 ? 3.4 2.4 0.23 1.6e+02 5 48 .. 97 145 .. 95 222 .. 0.66 3 ? 3.2 0.3 0.26 1.8e+02 18 56 .. 217 262 .. 191 269 .. 0.66 4 ? 0.0 0.3 2.6 1.8e+03 47 47 .. 301 301 .. 243 375 .. 0.54 5 ! 7.9 0.7 0.0092 6.4 3 51 .. 423 483 .. 421 493 .. 0.75 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0044 TPR-S 2 ydeavelleklla.pedaelqeqlalalarlgdreealevleellee 47 + ea++ ++++ + d elq++ a l+rl++++eal+ l++++e FUN_001477-T1 61 FREALDVINSAPKkGVDIELQFEKAYSLYRLNKTQEALNTLNAIEEL 107 45677777777666667799999999999999999999999998865 PP == domain 2 score: 3.4 bits; conditional E-value: 0.23 TPR-S 5 avellekllapedaelqeqlalalarlgdreealevleellee......k 48 a++ l+++++ +++ +e+ a++l+rl+d+ + l++ ++l+++ FUN_001477-T1 97 ALNTLNAIEE-LKEHEKELKAQVLYRLEDYHACLKLYKDLIKNsqddygD 145 4455555533.555779999********************9775445431 PP == domain 3 score: 3.2 bits; conditional E-value: 0.26 TPR-S 18 a.........elqeqlalalarlgdreealevleelleekedaEtlgl 56 ++ qla +++ +g+ +ea ++ +++l++ + l+l FUN_001477-T1 217 GeeefeaemgIVRVQLAYVYQLQGKNDEAQKLYNQVLKS--KPNDLAL 262 044455555567889999999999**********99988..5544444 PP == domain 4 score: 0.0 bits; conditional E-value: 2.6 TPR-S 47 e 47 + FUN_001477-T1 301 S 301 1 PP == domain 5 score: 7.9 bits; conditional E-value: 0.0092 TPR-S 3 deavelleklla...pedaelqeqlalalar........lgdreealevleelleeke.da 51 +av+ l+++ + +++ +++ +l l r +g+ +ea ++le+l++e d FUN_001477-T1 423 SAAVDILDEAVEhaqKNKDTMRQSEVLSLMRenvsyklqHGRAKEAVDMLEKLHKEDPtDV 483 6788888888885533333888888888888889999999**************8822344 PP >> Iml2-TPR_39 Iml2/Tetratricopeptide repeat protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.4 0.14 98 268 320 .. 82 134 .. 79 140 .. 0.85 2 ! 7.5 0.1 0.0029 2 40 67 .. 182 209 .. 178 227 .. 0.88 3 ? -2.7 0.0 3.8 2.6e+03 269 294 .. 231 256 .. 226 258 .. 0.81 4 ! 11.1 0.2 0.00024 0.17 242 292 .. 316 366 .. 294 378 .. 0.85 5 ? -0.2 0.1 0.63 4.4e+02 50 94 .. 422 460 .. 408 495 .. 0.60 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.14 Iml2-TPR_39 268 lfeariellkgnldeAlelleeliesqselkqvhhlcyfelalclvflhkykq 320 +++a + + +eAl++l+++ e +++ k++++ +++ l +++l+ yk+ FUN_001477-T1 82 FEKAYSLYRLNKTQEALNTLNAIEELKEHEKELKAQVLYRLEDYHACLKLYKD 134 55565566667899**************************9999999999986 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0029 Iml2-TPR_39 40 eAvltfepedikkasealkeaekvceks 67 A l + ++di++a e+lk+ae++ceks FUN_001477-T1 182 SACLSLGENDIEAAEEKLKKAEELCEKS 209 589999********************97 PP == domain 3 score: -2.7 bits; conditional E-value: 3.8 Iml2-TPR_39 269 feariellkgnldeAlelleeliesq 294 + a ++ l+g+ deA++l++++++s+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVLKSK 256 567788999*********99998876 PP == domain 4 score: 11.1 bits; conditional E-value: 0.00024 Iml2-TPR_39 242 geapleeaeelLkklrkryPkgallllfeariellkgnldeAlelleelie 292 + +le++ +l l+++yP++ l++a ++ +++ +A+e+l++ e FUN_001477-T1 316 HTNQLEACRNLTSTLEAKYPESDFPCLMRASLLHREKQSAKAVEVLKNYAE 366 467899****************************************97654 PP == domain 5 score: -0.2 bits; conditional E-value: 0.63 Iml2-TPR_39 50 ikkasealkeaekvceksrkkaqvvevskqstsdslyeeeleaev 94 + +a + l+ea + ++k+++ ++ e + sl+ e++ +++ FUN_001477-T1 422 VSAAVDILDEAVEHAQKNKDTMRQSE------VLSLMRENVSYKL 460 45566666666666666666655555......2233334433333 PP >> PknG_TPR Protein kinase G tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.1 1 6.9e+02 108 170 .. 240 264 .. 187 305 .. 0.63 2 ? 3.9 0.0 0.037 26 85 121 .. 364 400 .. 342 406 .. 0.72 3 ! 11.3 0.3 0.00021 0.14 193 270 .. 407 482 .. 403 493 .. 0.74 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1 PknG_TPR 108 GevakarelldrlaaekaadWRldWyrglaeLlagdyeeAvaeFdevlavlPGEiaPklALAa 170 G+ +eA++ +++vl+ P lALAa FUN_001477-T1 240 GK----------------------------------NDEAQKLYNQVLKSKPN----DLALAA 264 22..................................33333333333333332....234444 PP == domain 2 score: 3.9 bits; conditional E-value: 0.037 PknG_TPR 85 adgvdaeeslelkLaevRahldlGevakarelldrla 121 + + + ++ +++kL++v l +G++++a ++l++++ FUN_001477-T1 364 YAECHEDSAMNVKLTLVQLYLAQGNIGEACNTLRSVK 400 33445566799*******************9999875 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00021 PknG_TPR 193 gvvsAaFGlaRalaaaGdrdaAvaaLde.vpaaSrhfttArltavllllsgrpvaelteaelreaarrvealpeteeRa 270 gvvsA ++ Gd++aAv Lde v++a ++ t r + vl l++++ +l++ + +ea+ +e+l+++++ FUN_001477-T1 407 GVVSALV---TLYSHIGDVSAAVDILDEaVEHAQKNKDTMRQSEVLSLMRENVSYKLQHGRAKEAVDMLEKLHKEDPTD 482 5566543...345778888888888887577788888888888888888888888888888888888888888777654 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.7 1.9e+03 24 37 .. 26 39 .. 19 44 .. 0.82 2 ? -0.0 0.1 2.1 1.4e+03 9 22 .. 85 98 .. 84 99 .. 0.88 3 ? -1.2 0.1 4.7 3.2e+03 9 27 .. 116 134 .. 116 137 .. 0.71 4 ? 0.2 0.2 1.7 1.2e+03 17 30 .. 198 211 .. 192 212 .. 0.86 5 ! 10.2 0.1 0.0012 0.86 7 30 .. 231 254 .. 228 256 .. 0.91 6 ? 0.6 0.0 1.3 8.7e+02 8 22 .. 379 393 .. 375 400 .. 0.86 7 ? 4.3 0.0 0.088 61 8 30 .. 412 434 .. 410 438 .. 0.91 8 ? -0.2 0.1 2.2 1.6e+03 16 27 .. 463 474 .. 458 479 .. 0.79 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.7 TPR_10 24 lleealairervlG 37 +e+al+i+ ++l FUN_001477-T1 26 NFEKALKIANKILQ 39 589*****999986 PP == domain 2 score: -0.0 bits; conditional E-value: 2.1 TPR_10 9 analraqgryeeAe 22 a l+++++ +eA+ FUN_001477-T1 85 AYSLYRLNKTQEAL 98 6789*********8 PP == domain 3 score: -1.2 bits; conditional E-value: 4.7 TPR_10 9 analraqgryeeAeellee 27 a++l+++ +y++ ++l+++ FUN_001477-T1 116 AQVLYRLEDYHACLKLYKD 134 6788888888877777665 PP == domain 4 score: 0.2 bits; conditional E-value: 1.7 TPR_10 17 ryeeAeelleeala 30 +++ Aeel+e++l+ FUN_001477-T1 198 KLKKAEELCEKSLR 211 6778*******997 PP == domain 5 score: 10.2 bits; conditional E-value: 0.0012 TPR_10 7 nLanalraqgryeeAeelleeala 30 +La +++ qg+ +eA +l+ ++l+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVLK 254 79*****************99986 PP == domain 6 score: 0.6 bits; conditional E-value: 1.3 TPR_10 8 LanalraqgryeeAe 22 L +++ aqg+ eA FUN_001477-T1 379 LVQLYLAQGNIGEAC 393 8899*******9996 PP == domain 7 score: 4.3 bits; conditional E-value: 0.088 TPR_10 8 LanalraqgryeeAeelleeala 30 L +++++ g+ +A+++l+ea++ FUN_001477-T1 412 LVTLYSHIGDVSAAVDILDEAVE 434 8899*****************96 PP == domain 8 score: -0.2 bits; conditional E-value: 2.2 TPR_10 16 gryeeAeellee 27 gr +eA+++le+ FUN_001477-T1 463 GRAKEAVDMLEK 474 888899988886 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 6.9 4.8e+03 42 62 .. 342 362 .. 299 386 .. 0.62 2 ? 14.4 0.2 6.2e-05 0.043 43 75 .. 411 443 .. 343 454 .. 0.86 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 6.9 ANAPC5 42 lnlailhadfghneeAvkaie 62 l +a+l ++ ++ ++Av+ ++ FUN_001477-T1 342 LMRASLLHREKQSAKAVEVLK 362 444444444444444444444 PP == domain 2 score: 14.4 bits; conditional E-value: 6.2e-05 ANAPC5 43 nlailhadfghneeAvkaieeaiklArenkDta 75 +l++l++++g+ +Av+ + ea++ A+ nkDt FUN_001477-T1 411 ALVTLYSHIGDVSAAVDILDEAVEHAQKNKDTM 443 5889***************************96 PP >> Cdc6_lid Cdc6 AAA+ ATPase-type lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.0013 0.89 17 56 .. 404 442 .. 396 450 .. 0.77 2 ? 0.5 0.0 1.2 8.1e+02 32 45 .. 461 474 .. 445 475 .. 0.86 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0013 Cdc6_lid 17 lseeviplvAalaaqesGDaRrAldlLrkAgelAeregse 56 ++ +v++ l GD+ A d+L +A e+A++++++ FUN_001477-T1 404 YKPGVVSALVTLYS-HIGDVSAAVDILDEAVEHAQKNKDT 442 55556655555555.68******************99876 PP == domain 2 score: 0.5 bits; conditional E-value: 1.2 Cdc6_lid 32 esGDaRrAldlLrk 45 ++G a+ A d+L+k FUN_001477-T1 461 QHGRAKEAVDMLEK 474 59**********86 PP >> HemY_N HemY protein N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.042 29 65 91 .. 182 208 .. 172 212 .. 0.87 2 ? -1.2 0.0 4.4 3.1e+03 68 94 .. 382 408 .. 356 414 .. 0.79 3 ? 4.0 0.0 0.11 75 69 100 .. 459 492 .. 455 495 .. 0.90 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.042 HemY_N 65 eGllalaeGdwaqAeklaakaakllea 91 ++ l+l+e d ++Ae++++ka++l e+ FUN_001477-T1 182 SACLSLGENDIEAAEEKLKKAEELCEK 208 67899****************998776 PP == domain 2 score: -1.2 bits; conditional E-value: 4.4 HemY_N 68 lalaeGdwaqAeklaakaaklleapll 94 l la+G+ +A + ++ ++l+ +p++ FUN_001477-T1 382 LYLAQGNIGEACNTLRSVKDLAYKPGV 408 568999*****9999999998888654 PP == domain 3 score: 4.0 bits; conditional E-value: 0.11 HemY_N 69 alaeGdwaqAeklaakaakllea..pllnyllaA 100 +l +G++++A ++ k k++++ ++l++l++A FUN_001477-T1 459 KLQHGRAKEAVDMLEKLHKEDPTdvKTLAQLIKA 492 6899*****************8878999999998 PP >> ATP13 Mitochondrial ATPase expression # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.021 14 49 84 .. 7 42 .. 2 71 .. 0.87 2 ? 2.2 0.0 0.33 2.3e+02 55 82 .. 408 435 .. 401 446 .. 0.87 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.021 ATP13 49 lyPtselLkaivssfsynndiesAlklvdkfskkYp 84 + Pt L++ + f+++ ++e+Alk+ +k+ ++ p FUN_001477-T1 7 AAPTIPQLFTELDRFGKDRNFEKALKIANKILQEKP 42 56888899999999****************998755 PP == domain 2 score: 2.2 bits; conditional E-value: 0.33 ATP13 55 lLkaivssfsynndiesAlklvdkfskk 82 ++ a+v+ +s+ +d++ A++++d+ +++ FUN_001477-T1 408 VVSALVTLYSHIGDVSAAVDILDEAVEH 435 7889******************987765 PP >> TPR_P4H Prolyl 4-hydroxylase peptide-substrate-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.2 8.5e+02 56 78 .. 25 47 .. 21 54 .. 0.86 2 ? 5.0 0.3 0.056 39 44 84 .. 78 120 .. 43 125 .. 0.66 3 ? 1.4 0.1 0.72 5e+02 50 74 .. 117 141 .. 108 151 .. 0.81 4 ? 0.9 0.0 1.1 7.3e+02 36 75 .. 219 259 .. 197 270 .. 0.78 5 ? 5.6 0.1 0.037 25 34 74 .. 438 481 .. 416 494 .. 0.56 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.2 TPR_P4H 56 gdlkraleLtkrllkldpehera 78 + ++al++++++l+ +p+++ a FUN_001477-T1 25 RNFEKALKIANKILQEKPDDKEA 47 6899************9998876 PP == domain 2 score: 5.0 bits; conditional E-value: 0.056 TPR_P4H 44 i.Ldy.LayalyqqgdlkraleLtkrllkldpeherakgnvky 84 i L++ ay+ly+ ++ ++al+ + + +l+ +++ k+ v y FUN_001477-T1 78 IeLQFeKAYSLYRLNKTQEALNTLNAIEELKEHEKELKAQVLY 120 35554259**************999999999888888887765 PP == domain 3 score: 1.4 bits; conditional E-value: 0.72 TPR_P4H 50 yalyqqgdlkraleLtkrllkldpe 74 ly+ d + l+L k l+k + + FUN_001477-T1 117 QVLYRLEDYHACLKLYKDLIKNSQD 141 5689999999999999999987655 PP == domain 4 score: 0.9 bits; conditional E-value: 1.1 TPR_P4H 36 ektvekvei.LdyLayalyqqgdlkraleLtkrllkldpeh 75 e+ + ++ i Lay + qg+ ++a +L +++lk +p++ FUN_001477-T1 219 EEFEAEMGIvRVQLAYVYQLQGKNDEAQKLYNQVLKSKPND 259 444455555134699999999************99999986 PP == domain 5 score: 5.6 bits; conditional E-value: 0.037 TPR_P4H 34 geektvekveiL....dyLayalyqqgdlkraleLtkrllkldpe 74 +++ t+ ++e+L + ++y l q+g k+a+++ ++l k dp+ FUN_001477-T1 438 KNKDTMRQSEVLslmrENVSYKL-QHGRAKEAVDMLEKLHKEDPT 481 34445555555411123344443.556666666666666666665 PP >> DUF4363 Domain of unknown function (DUF4363) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.7 0.62 4.3e+02 62 98 .. 77 113 .. 76 119 .. 0.81 2 ? -2.4 0.0 10 6.9e+03 27 43 .. 189 205 .. 180 210 .. 0.66 3 ? 12.1 0.1 0.00031 0.22 13 98 .. 372 458 .. 360 462 .. 0.89 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.62 DUF4363 62 nIeislaklkeyietkekeealaelaslklliehipe 98 +Ie+++ k+ ++ + + ++eal l+++++l eh +e FUN_001477-T1 77 DIELQFEKAYSLYRLNKTQEALNTLNAIEELKEHEKE 113 6888888999999999999999999999998888555 PP == domain 2 score: -2.4 bits; conditional E-value: 10 DUF4363 27 nenweeAekeldkleke 43 +++ e+Ae++l+k e+ FUN_001477-T1 189 ENDIEAAEEKLKKAEEL 205 66777777777776665 PP == domain 3 score: 12.1 bits; conditional E-value: 0.00031 DUF4363 13 kleeklekieeeienenweeAekeldklekeWnktkklwsilldHqeiDnIeislaklkeyietkek.eealaelaslklliehipe 98 ++ kl+ ++ ++ ++n eA ++l+++++ k + +++ + i +++ ++ l+e++e+ +k ++ + + ++l l+ e++ FUN_001477-T1 372 AMNVKLTLVQLYLAQGNIGEACNTLRSVKDLAYKPGVVSALVTLYSHIGDVSAAVDILDEAVEHAQKnKDTMRQSEVLSLMRENVSY 458 67889999*******************************************************977615688899999998888865 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 2.7 1.9e+03 19 44 .. 24 49 .. 20 67 .. 0.71 2 ? 8.9 0.3 0.0031 2.2 9 75 .. 81 148 .. 76 151 .. 0.85 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 2.7 Rapsyn_N 19 sndtekalrvWrkvlkktsdredkfr 44 + + ekal++ k+l++ d ++ ++ FUN_001477-T1 24 DRNFEKALKIANKILQEKPDDKEAYH 49 56789999999999998887777664 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0031 Rapsyn_N 9 kiekGlklyesndtekalrvWrkvlk.ktsdredkfrllGylitahsemGkykealefslaqlniaee 75 + ek ly+ n+t++al + + k ++e k ++l l h+ + yk++++ s + +e FUN_001477-T1 81 QFEKAYSLYRLNKTQEALNTLNAIEElKEHEKELKAQVLYRLEDYHACLKLYKDLIKNSQDDYGDERE 148 789*****************987643256788999*********************999887776665 PP >> Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.0059 4.1 15 37 .. 25 47 .. 22 54 .. 0.91 2 ? 0.1 0.1 2 1.4e+03 12 30 .. 120 138 .. 116 142 .. 0.86 3 ? -2.1 0.0 9.5 6.6e+03 18 33 .. 243 258 .. 239 260 .. 0.81 4 ? -0.2 0.0 2.5 1.7e+03 16 45 .. 461 491 .. 457 492 .. 0.71 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0059 Fis1_TPR_C 15 geYseArryvdalLeiePenrQa 37 +++++A+++++ +L+ P++++a FUN_001477-T1 25 RNFEKALKIANKILQEKPDDKEA 47 89*****************9998 PP == domain 2 score: 0.1 bits; conditional E-value: 2 Fis1_TPR_C 12 yklgeYseArryvdalLei 30 y+l +Y +++ + l++ FUN_001477-T1 120 YRLEDYHACLKLYKDLIKN 138 9********9999988875 PP == domain 3 score: -2.1 bits; conditional E-value: 9.5 Fis1_TPR_C 18 seArryvdalLeiePe 33 +eA ++ + +L+ P+ FUN_001477-T1 243 DEAQKLYNQVLKSKPN 258 6889999999999887 PP == domain 4 score: -0.2 bits; conditional E-value: 2.5 Fis1_TPR_C 16 eYseArryvdal..LeiePenrQaqeLkelie 45 ++ +A++ vd+l L++e + +++L +li+ FUN_001477-T1 461 QHGRAKEAVDMLekLHKE-DPTDVKTLAQLIK 491 478999999999545555.6677888888775 PP >> TPR_Slam Surface lipoprotein assembly modifier, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 6.9 4.7e+03 59 80 .. 23 44 .. 21 47 .. 0.86 2 ? -1.5 0.1 6.8 4.7e+03 54 76 .. 116 138 .. 80 142 .. 0.66 3 ? -1.8 0.0 8.3 5.7e+03 59 79 .. 195 215 .. 185 234 .. 0.65 4 ? 7.9 0.2 0.0079 5.5 52 80 .. 231 259 .. 218 278 .. 0.85 5 ? 2.4 0.1 0.41 2.8e+02 54 93 .. 345 385 .. 302 405 .. 0.65 6 ? 1.7 0.0 0.7 4.8e+02 59 81 .. 461 483 .. 437 499 .. 0.84 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 6.9 TPR_Slam 59 sqgnyaeAialYrellaekpdl 80 +++n+++A + ++l+ekpd FUN_001477-T1 23 KDRNFEKALKIANKILQEKPDD 44 5789999999999*****9985 PP == domain 2 score: -1.5 bits; conditional E-value: 6.8 TPR_Slam 54 AilarsqgnyaeAialYrellae 76 A ++ + ++y +lY+ l+++ FUN_001477-T1 116 AQVLYRLEDYHACLKLYKDLIKN 138 44555555666666666666665 PP == domain 3 score: -1.8 bits; conditional E-value: 8.3 TPR_Slam 59 sqgnyaeAialYrellaekpd 79 +++++++A +l ++ l+++pd FUN_001477-T1 195 AEEKLKKAEELCEKSLRDDPD 215 444555555555555555554 PP == domain 4 score: 7.9 bits; conditional E-value: 0.0079 TPR_Slam 52 aqAilarsqgnyaeAialYrellaekpdl 80 A + + qg+ +eA +lY ++l+ kp+ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQVLKSKPND 259 5688999*******************985 PP == domain 5 score: 2.4 bits; conditional E-value: 0.41 TPR_Slam 54 AilarsqgnyaeAialYrellaekpd.llpvrlqlAqaLfe 93 A l++++++ a+A++ ++ + + d + v+l l q +++ FUN_001477-T1 345 ASLLHREKQSAKAVEVLKNYAECHEDsAMNVKLTLVQLYLA 385 45555555555555555555554444233355555444333 PP == domain 6 score: 1.7 bits; conditional E-value: 0.7 TPR_Slam 59 sqgnyaeAialYrellaekpdll 81 ++g+++eA++ ++l++e+p FUN_001477-T1 461 QHGRAKEAVDMLEKLHKEDPTDV 483 67999************999754 PP >> DUF4919 Domain of unknown function (DUF4919) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 1 6.9e+02 68 94 .. 23 49 .. 15 67 .. 0.82 2 ? 4.0 0.3 0.087 60 42 71 .. 82 111 .. 79 126 .. 0.82 3 ? -0.9 0.0 2.8 1.9e+03 95 115 .. 231 251 .. 181 260 .. 0.74 4 ? 5.6 0.3 0.028 20 58 105 .. 451 498 .. 434 504 .. 0.78 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1 DUF4919 68 keeelkeiiklaeklldkfPfdlrqln 94 k++++++++k+a+k+l++ P d + + FUN_001477-T1 23 KDRNFEKALKIANKILQEKPDDKEAYH 49 67899*************997766655 PP == domain 2 score: 4.0 bits; conditional E-value: 0.087 DUF4919 42 FqekYkpykvskekekleelyqkkkikeee 71 F+++Y+ y+ +k +e l++l + +++ke+e FUN_001477-T1 82 FEKAYSLYRLNKTQEALNTLNAIEELKEHE 111 99****************997777777655 PP == domain 3 score: -0.9 bits; conditional E-value: 2.8 DUF4919 95 lllyaykllkdkesakkvskk 115 l+y+y+l++++++a+k+ ++ FUN_001477-T1 231 QLAYVYQLQGKNDEAQKLYNQ 251 468889988888888887665 PP == domain 4 score: 5.6 bits; conditional E-value: 0.028 DUF4919 58 leelyqkkkikeeelkeiiklaeklldkfPfdlrqlnlllyaykllkd 105 l++ ++k++ ke++++ ekl ++ P d+++l l+ ay + FUN_001477-T1 451 LMRENVSYKLQHGRAKEAVDMLEKLHKEDPTDVKTLAQLIKAYSCVNP 498 33336788999999****************************987654 PP >> TPR_3 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.1 2 1.4e+03 8 21 .. 85 98 .. 81 100 .. 0.59 2 ? 7.2 1.6 0.012 8.3 7 24 .. 232 249 .. 231 253 .. 0.91 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 2 TPR_3 8 AatfylkgkyqeAr 21 A+++y k qeA+ FUN_001477-T1 85 AYSLYRLNKTQEAL 98 56666666666665 PP == domain 2 score: 7.2 bits; conditional E-value: 0.012 TPR_3 7 lAatfylkgkyqeArely 24 lA++++l+gk +eA ly FUN_001477-T1 232 LAYVYQLQGKNDEAQKLY 249 8*************9887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (506 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2166 (0.0847915); expected 510.9 (0.02) Passed bias filter: 879 (0.0344099); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 40 (0.00156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 37 [number of targets reported over threshold] # CPU time: 0.43u 0.40s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 4798.64 // Query: FUN_001478-T1 [L=175] Description: FUN_001478 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-18 65.0 8.8 8.2e-18 65.0 8.8 2.6 2 SRP72 SRP72 RNA-binding domain ------ inclusion threshold ------ 0.51 11.3 5.7 1 10.3 5.7 1.5 1 CCDC53 Subunit CCDC53 of WASH complex Domain annotation for each model (and alignments): >> SRP72 SRP72 RNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.0 8.8 6.4e-22 8.2e-18 8 57 .. 58 105 .. 47 106 .. 0.72 2 ? -3.1 7.8 1.2 1.5e+04 15 29 .. 159 173 .. 108 175 .] 0.70 Alignments for each domain: == domain 1 score: 65.0 bits; conditional E-value: 6.4e-22 SRP72 8 spetakeeevkkkkkkkkrkrkgklPKnfdpevtpDPERWLPrreRSsYr 57 e ++e+ k++k+++++gklPKn++p+v+pDPERW+P+reRS+Y+ FUN_001478-T1 58 EMEDLRQEIIM--KRRKRKRKRGKLPKNYNPDVDPDPERWIPKRERSYYK 105 22333333333..4688888889**************************9 PP == domain 2 score: -3.1 bits; conditional E-value: 1.2 SRP72 15 eevkkkkkkkkrkrk 29 + + + +kk+r +k FUN_001478-T1 159 QHQPQAARKKQRPKK 173 111112223333333 PP >> CCDC53 Subunit CCDC53 of WASH complex # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 5.7 8.1e-05 1 8 103 .. 2 161 .. 1 175 [] 0.66 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 8.1e-05 CCDC53 8 tvqfLN.rFsavcEekLveverrlqkleatlaiLeakLsSip...gleevtaeaaeta...................................... 61 t++fLN + ++ ekL+++ ++ q+ + Le Ls+ g +++++e a FUN_001478-T1 2 TITFLNwSYQNSFSEKLTSLDTSSQDTTLDVDALELSLSASGsryGRTKAKQE----Advemedlrqeiimkrrkrkrkrgklpknynpdvdpdpe 93 899***77999***************************975433322222222....12455678889**************************** PP CCDC53 62 ........................................aasnaepseessaeeaeaaaqaeepseaeeeaeeeeeeeees 103 + +++ ++a++p ++++ ++++++++++ FUN_001478-T1 94 rwipkrersyykgkrqkkgasvgkgtqgaaapaeassspkT--------------SRSPKPASPPGTPSAGGASANASRQHQ 161 ************99999999999986544444433333331..............222222222222222222222222122 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (175 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1170 (0.0458015); expected 510.9 (0.02) Passed bias filter: 429 (0.0167939); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1749.84 // Query: FUN_001479-T1 [L=471] Description: FUN_001479 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-13 49.6 0.2 7e-13 48.9 0.2 1.4 1 zf-DBF DBF zinc finger 5.3e-07 30.2 0.0 1.3e-06 29.0 0.0 1.6 1 BRCT BRCA1 C Terminus (BRCT) domain ------ inclusion threshold ------ 0.046 14.0 0.1 0.046 14.0 0.1 2.2 2 LUC7 LUC7 N_terminus 0.074 13.1 0.6 0.15 12.2 0.6 1.6 1 zf-C2H2_14 CIZ1-like, C2H2-type zinc finger 0.2 11.2 7.0 0.027 14.0 2.5 1.8 2 ODAD1_CC ODAD1 central coiled coil region 1.9 7.3 10.2 0.18 10.7 2.1 2.1 2 DUF1631 Protein of unknown function (DUF1631) 7.2 7.4 6.4 90 3.9 6.4 2.5 1 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding Domain annotation for each model (and alignments): >> zf-DBF DBF zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.9 0.2 1.9e-16 7e-13 2 44 .. 251 293 .. 250 294 .. 0.97 Alignments for each domain: == domain 1 score: 48.9 bits; conditional E-value: 1.9e-16 zf-DBF 2 kpGYCEnCrekfedleeHiesekHrkFaendsnfkelDelisk 44 k+GYCE C ++ l++H++s++H+ a+ ++ ++elD+li++ FUN_001479-T1 251 KKGYCELCDTHYIGLQKHVNSRRHKLLATHKDTYAELDRLIAR 293 9****************************************86 PP >> BRCT BRCA1 C Terminus (BRCT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 0.0 3.5e-10 1.3e-06 4 55 .. 45 95 .. 42 120 .. 0.90 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 3.5e-10 BRCT 4 klfsgltfviggldseerdelkelieklGgkvtdslskktthvivgepeart 55 ++++g++f++ + + el+++++++Gg v++ lsk+ t+vi+++p ++t FUN_001479-T1 45 SPLEGKSFFLHVHSPGKARELERKLKEFGGVVEKFLSKELTCVITDQP-TTT 95 699*******99999999******************************.443 PP >> LUC7 LUC7 N_terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.1 1.3e-05 0.046 156 206 .. 143 195 .. 109 197 .. 0.68 2 ? -2.8 2.4 1.7 6.2e+03 181 229 .. 246 288 .. 224 313 .. 0.48 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.3e-05 LUC7 156 kkveelkeekeelekeleel...................ekesaasqekklevCevCGaflivnDadrRl 206 ++ + +k++++++++k +vC Gafl v+D++rR FUN_001479-T1 143 DN-----------------AkkwgiqvkpveqvlkwintQKKQQDTNQSKGRVCSLKGAFLKVEDHSRRY 195 22.................2344444444444555556678889999*********************97 PP == domain 2 score: -2.8 bits; conditional E-value: 1.7 LUC7 181 asqekklevCevCGaflivnDadrRladHltGKqHlGyakirekleelk 229 +++ +k +Ce C i ++H++ + H a+ +++++el FUN_001479-T1 246 RKSTEKKGYCELCDTHYIGL------QKHVNSRRHKLLATHKDTYAELD 288 44455556666665555443......33333333333333333333333 PP >> zf-C2H2_14 CIZ1-like, C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.6 4.1e-05 0.15 4 28 .. 254 277 .. 251 279 .. 0.87 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 4.1e-05 zf-C2H2_14 4 WCatCqlhFtGdlieHRRTkeHkll 28 +C C++h+ G l H +++Hkll FUN_001479-T1 254 YCELCDTHYIG-LQKHVNSRRHKLL 277 9*********9.8999999999987 PP >> ODAD1_CC ODAD1 central coiled coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.2 0.72 2.6e+03 152 173 .. 151 172 .. 114 190 .. 0.57 2 ? 14.0 2.5 7.4e-06 0.027 84 147 .. 269 332 .. 266 343 .. 0.82 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.72 ODAD1_CC 152 svesyeeafekikeltgeedld 173 +v+ e++++ i++ +++d++ FUN_001479-T1 151 QVKPVEQVLKWINTQKKQQDTN 172 4555566666666555555554 PP == domain 2 score: 14.0 bits; conditional E-value: 7.4e-06 ODAD1_CC 84 lkekaekdlaqynaEmkelqriidherklkeFlkiKaqersedeeelekrekkakekaekkrke 147 ++ +++k la ++ el+r+i++ ++lkeF + ++r+++ + + +++ ++++ + + ++ FUN_001479-T1 269 VNSRRHKLLATHKDTYAELDRLIARGKTLKEFKDERIKKRNSEAQIQTRSRTRSRSPTSTASTS 332 678999***********************************99888877777776655554444 PP >> DUF1631 Protein of unknown function (DUF1631) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 1.2 0.036 1.3e+02 215 340 .. 93 232 .. 68 249 .. 0.65 2 ? 10.7 2.1 4.8e-05 0.18 185 258 .. 275 358 .. 270 394 .. 0.86 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.036 DUF1631 215 rrrqsrrasaseagaaeeeqesqaaPasaasaeageaeaqaaaaaaaekal.......lfsaLqqLlsaarsqaaaaaqaassaee.......... 293 +q++++ ++ +g+ +++ ++ + P++a++ +++ ++++++a+ + +++ ++q l+ + q++++++++s+++ FUN_001479-T1 93 TTTQRSASGRKGSGSLATDLTNTRGPSRAQAILQKSVRQKKQPAKSTDVLDnakkwgiQVKPVEQVLKWINTQKKQQDTNQSKGRVcslkgaflkv 188 334444555556777888999999999999999998888887766655444888899977777777777777777776666655445566677666 PP DUF1631 294 eapalssaeLlsaLsrlqqqaaaeaaagaeaeaadlrealanvlrqq 340 e+++ + + L++ L +q + a+ + ++ d ++ ++ r++ FUN_001479-T1 189 EDHSRRYKPLVKELRVWPQLNL---DAPPGFSPFDEPVSMRTRSRSS 232 5555555666666666666655...4444444444444444444444 PP == domain 2 score: 10.7 bits; conditional E-value: 4.8e-05 DUF1631 185 qvlaelgelyeelNqlLieaGvLPelklaar.........rrqsrrasaseagaaeeeqesqaaPasaasaeag.eaeaqaaaa 258 ++la + y+el++l ++ L e+k ++ +++sr++s+s+++ a++ ++++++P++++s+++g +++++++++ FUN_001479-T1 275 KLLATHKDTYAELDRLIARGKTLKEFKDERIkkrnseaqiQTRSRTRSRSPTSTASTSPKRKSTPSATTSSPEGsNGRTTSQQS 358 67889999********************999999****99999999999999999***********999999993444444443 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 6.4 0.025 90 3 27 .] 254 275 .. 254 275 .. 0.93 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.025 zf-C2H2_jaz 3 YCvlCdKyFksenalqnHlkSKkHK 27 YC+lCd +++ lq H++S+ HK FUN_001479-T1 254 YCELCDTHYIG---LQKHVNSRRHK 275 9*****99997...99********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (471 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1538 (0.0602075); expected 510.9 (0.02) Passed bias filter: 586 (0.0229399); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.40 # Mc/sec: 4722.76 // Query: FUN_001480-T1 [L=217] Description: FUN_001480 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-23 81.4 4.4 6.9e-23 80.7 4.4 1.3 1 Homeodomain Homeodomain 0.0051 17.1 0.1 0.012 15.9 0.1 1.6 1 Homeobox_KN Homeobox KN domain Domain annotation for each model (and alignments): >> Homeodomain Homeodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.7 4.4 5.4e-27 6.9e-23 1 57 [] 152 208 .. 152 208 .. 0.98 Alignments for each domain: == domain 1 score: 80.7 bits; conditional E-value: 5.4e-27 Homeodomain 1 rrkRttftkeqleeLekeFeenrypsaeereeLAkklgLserqVkvWFqNrRakekk 57 +r Rt+ft+eqle+LekeF++++y+ +er LA++l+Lse+qVkvWFqNrR k++k FUN_001480-T1 152 KRIRTIFTPEQLERLEKEFDRQQYMVGAERHFLAASLNLSETQVKVWFQNRRIKWRK 208 788*****************************************************8 PP >> Homeobox_KN Homeobox KN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 9.3e-07 0.012 15 38 .. 180 203 .. 178 205 .. 0.92 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 9.3e-07 Homeobox_KN 15 eKeeLaketglsrkqisnWFiNaR 38 e+ La++ +ls++q++ WF N R FUN_001480-T1 180 ERHFLAASLNLSETQVKVWFQNRR 203 7889******************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (217 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 911 (0.0356626); expected 510.9 (0.02) Passed bias filter: 504 (0.0197299); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2136.59 // Query: FUN_001481-T1 [L=332] Description: FUN_001481 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-11 43.2 1.1 1.2e-09 39.4 1.1 2.2 1 Metallophos Calcineurin-like phosphoesterase 1.1e-07 32.6 0.1 0.00025 21.6 0.1 2.3 2 Metallophos_2 Calcineurin-like phosphoesterase superfamily d ------ inclusion threshold ------ 0.28 11.0 0.0 0.92 9.3 0.0 1.8 2 Metallophos_3 Metallophosphoesterase, calcineurin superfamil Domain annotation for each model (and alignments): >> Metallophos Calcineurin-like phosphoesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.4 1.1 1.4e-13 1.2e-09 2 109 .. 18 164 .. 17 279 .. 0.50 Alignments for each domain: == domain 1 score: 39.4 bits; conditional E-value: 1.4e-13 Metallophos 2 rilvigDlHgegqfddllellekl.rpeekpdlvliaGDlvdrgsletevlellallvkyipvflvrGNHd......................... 71 ri +i+D+H + + l+l+e ++ ++d++++aGD++d +sl + vl+ l ++ +v v+GNH+ FUN_001481-T1 18 RIFAISDIH--VDIKENLRLVESWsGSDFRNDVLIVAGDVTDNTSLLKTVLKALVEKFS--KVCYVPGNHElwirqtedascyedsigkfhsirei 109 899******..99999999996665666799*************777778888777777..8*********8888877777666555555555555 PP Metallophos 72 ..........fydeclrkygelnllarpwkaf..vevfnllplaaligg.....k 109 + c + ++ + ++ w+a ++ n l++a+ +++ k FUN_001481-T1 110 cetigvhtrpIKVQCCNDNAAWVVPMFSWYAKpeDDFENSLYVAGEMEDaelsnK 164 5555555554222333333333333222222233333344444443333333333 PP >> Metallophos_2 Calcineurin-like phosphoesterase superfamily domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 3e-08 0.00025 2 60 .. 18 91 .. 17 128 .. 0.70 2 ! 8.9 0.0 0.00024 2 94 130 .. 257 290 .. 213 302 .. 0.83 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 3e-08 Metallophos_2 2 kigivSDtH....dnlalpeaalerlkevvdlvihaGDl.vapevleeleela.....pvtaVrGnnD......l 60 +i +SD+H +nl+l+e++ + d +i+aGD+ + + l+ + ++ +v++V Gn++ + FUN_001481-T1 18 RIFAISDIHvdikENLRLVESWSGSDFRN-DVLIVAGDVtDNTSLLKTVLKALvekfsKVCYVPGNHElwirqtE 91 6889*****76666666777666666666.9********6333344444443345569**********7543330 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00024 Metallophos_2 94 erlaellreaeegkadvvvyGHtHepeveeeggvllv 130 +++++++r+ g++ v vyGH H+ + +++v+++ FUN_001481-T1 257 KSIEKQIRR--LGSK-VHVYGHQHRNRDRVIDDVRYI 290 555666666..5555.99************9999887 PP >> Metallophos_3 Metallophosphoesterase, calcineurin superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.00011 0.92 3 52 .. 14 65 .. 12 93 .. 0.84 2 ? -1.7 0.0 0.24 2.1e+03 196 223 .. 253 280 .. 227 286 .. 0.85 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00011 Metallophos_3 3 klvrkvlaisdlkgevellerlveviedk..spDllvlvGdlvkaeakadey 52 +++ ++ aisd++ ++ rlve + D+l++ Gd+ + + + FUN_001481-T1 14 QMMSRIFAISDIHVDIKENLRLVESWSGSdfRNDVLIVAGDVTDNTSLLKTV 65 6889***********999999999876443389*********9998776655 PP == domain 2 score: -1.7 bits; conditional E-value: 0.24 Metallophos_3 196 eagsevvaelvktlnPevvvvghavkeh 223 ags+ + + ++ l +v v gh ++++ FUN_001481-T1 253 FAGSKSIEKQIRRLGSKVHVYGHQHRNR 280 57999999999***********999877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 857 (0.0335486); expected 510.9 (0.02) Passed bias filter: 761 (0.0297906); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3211.79 // Query: FUN_001481-T2 [L=257] Description: FUN_001481 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (257 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 752 (0.0294382); expected 510.9 (0.02) Passed bias filter: 671 (0.0262674); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2555.86 // Query: FUN_001482-T1 [L=203] Description: FUN_001482 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-22 79.5 3.3 3.5e-22 78.5 3.3 1.6 1 Homeodomain Homeodomain 6.5e-05 23.2 0.3 0.012 16.0 0.1 2.5 2 Homeobox_KN Homeobox KN domain ------ inclusion threshold ------ 0.015 14.9 1.2 0.021 14.5 1.2 1.1 1 Redic1-like Regulator of DNA class I crossover intermediates Domain annotation for each model (and alignments): >> Homeodomain Homeodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.5 3.3 4.1e-26 3.5e-22 1 57 [] 131 187 .. 131 187 .. 0.99 Alignments for each domain: == domain 1 score: 78.5 bits; conditional E-value: 4.1e-26 Homeodomain 1 rrkRttftkeqleeLekeFeenrypsaeereeLAkklgLserqVkvWFqNrRakekk 57 rr Rt+ft+ ql Le++Fe+n+y+ +er++LA+ l+Lse+qVkvWFqNrR+k+k+ FUN_001482-T1 131 RRVRTAFTPFQLLCLETSFEKNHYVVGSERKQLASYLKLSETQVKVWFQNRRTKWKR 187 899*****************************************************8 PP >> Homeobox_KN Homeobox KN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.9 0.0 0.0041 35 4 14 .. 84 94 .. 82 98 .. 0.79 2 ! 16.0 0.1 1.4e-06 0.012 15 39 .. 159 183 .. 157 184 .. 0.93 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0041 Homeobox_KN 4 ehlknPYPsee 14 + +++PYPs+ FUN_001482-T1 84 DKFRWPYPSQS 94 6689*****86 PP == domain 2 score: 16.0 bits; conditional E-value: 1.4e-06 Homeobox_KN 15 eKeeLaketglsrkqisnWFiNaRr 39 e+++La +ls++q++ WF N R FUN_001482-T1 159 ERKQLASYLKLSETQVKVWFQNRRT 183 899********************96 PP >> Redic1-like Regulator of DNA class I crossover intermediates 1-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 1.2 2.4e-06 0.021 109 178 .. 93 162 .. 89 185 .. 0.87 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 2.4e-06 Redic1-like 109 denhstdrlirsiftvpeltfsnstfnktsypekcqpnkkyqkeynsnerndlstsfekdcYpassekkg 178 + ++ t + +++ t+pe s+ t ++s + q +++++ ++ l tsfek+ Y ++se+k+ FUN_001482-T1 93 QSSRGTRQSCTEVRTNPEKPQSSGTAAQASQKSGNQKQRRVRTAFTPFQLLCLETSFEKNHYVVGSERKQ 162 55666777778899******************************************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1097 (0.0429438); expected 510.9 (0.02) Passed bias filter: 611 (0.0239186); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 2092.57 // Query: FUN_001483-T1 [L=496] Description: FUN_001483 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-76 255.3 0.0 8.4e-76 254.8 0.0 1.2 1 ATP-synt_ab ATP synthase alpha/beta family, nucleotide-bin 7.5e-35 119.5 0.3 3.4e-34 117.4 0.0 2.2 2 ATP-synt_VA_C C-terminal domain of V and A type ATP synthase 7e-15 55.8 0.2 1.5e-14 54.7 0.2 1.6 1 ATP-synt_ab_N ATP synthase alpha/beta family, beta-barrel do ------ inclusion threshold ------ 0.21 11.4 0.0 0.31 10.8 0.0 1.2 1 Rtf2 Rtf2 RING-finger Domain annotation for each model (and alignments): >> ATP-synt_ab ATP synthase alpha/beta family, nucleotide-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 254.8 0.0 1.3e-79 8.4e-76 1 213 [] 156 382 .. 156 382 .. 0.98 Alignments for each domain: == domain 1 score: 254.8 bits; conditional E-value: 1.3e-79 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF ATP-synt_ab 1 GikaiDallpigkGqrlgifggsgvGktvlaatiakqa.sa............dvvvvyvliGergrevaefleeleeeealkrtvvvvatsdepa 83 Gi+aiD++++i++Gq+++if+++g++++ +aa+i++qa ++++v++++G + ++++ f +++ee++ +++++++++ +++p+ FUN_001483-T1 156 GISAIDTMNSIARGQKIPIFSAAGLPHNDIAAQICRQAgLVkfkkgvlddhsdNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPT 251 9************************************85337**********98****************************************** PP xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF ATP-synt_ab 84 larllapytaltiAEyfrd.qgkdVllildsltrfaeAlreislalgeppgregYpgsvfselarllERagkvkekkgsiTalpivlvegdDitdp 178 ++r+++p++alt+AE++++ +++Vl+il++++++aeAlre+s+a++e+pgr+g+pg+++++la+++ERag+v++++gsiT++pi+++++dDit+p FUN_001483-T1 252 IERIITPRLALTTAEFLAYqCENHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHP 347 *******************8899************************************************************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF ATP-synt_ab 179 ipdavisildgqivLsrelaekgiyPAidvlkSvS 213 ipd +++i++gqi+++r+l+++++yP+i+vl+S+S FUN_001483-T1 348 IPDLTGYITEGQIYVDRQLHNRQVYPPINVLPSLS 382 *********************************99 PP >> ATP-synt_VA_C C-terminal domain of V and A type ATP synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 0.51 3.2e+03 49 67 .. 221 239 .. 219 248 .. 0.71 2 ! 117.4 0.0 5.3e-38 3.4e-34 2 101 .] 388 487 .. 387 487 .. 0.98 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.51 ATP-synt_VA_C 49 lefaklfeedFlqQnafes 67 +e+a+ f++dF + +++e+ FUN_001483-T1 221 METARFFKQDFEENGSMEN 239 6778888888866666555 PP == domain 2 score: 117.4 bits; conditional E-value: 5.3e-38 ATP-synt_VA_C 2 gigegktredhsdlrnqlkallaeekelqeivqlvGedaLseeDkltlefaklfeedFlqQnafesrdieepldkqwellsilpreelkrikeell 97 +igeg+tr+dh+d++nql+a +a +k++q+++++vGe+aL++eD l+lef +fe++F++Q+ +e+r+++++ld++w+ll+i+p+e+lkri+++ l FUN_001483-T1 388 AIGEGMTRKDHADVSNQLYANYAIGKDVQAMKAVVGEEALTSEDLLYLEFLSKFEKNFISQGTYENRSVFDSLDLGWSLLRIFPKEMLKRIPQSIL 483 69********************************************************************************************99 PP ATP-synt_VA_C 98 dkyy 101 ++yy FUN_001483-T1 484 AEYY 487 9997 PP >> ATP-synt_ab_N ATP synthase alpha/beta family, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.7 0.2 2.4e-18 1.5e-14 1 69 [] 33 99 .. 33 99 .. 0.97 Alignments for each domain: == domain 1 score: 54.7 bits; conditional E-value: 2.4e-18 ATP-synt_ab_N 1 ivqviGpvvdvedgigrlpgllnalevelvefgslvlgevlnleedkVriqvfegtsGlkr.GdeVkrTG 69 ++ v+Gp+v+ +d+++ p+ +++++ l++ gs++ g+vl++++ k+++qvfegtsG++ +++++TG FUN_001483-T1 33 VSGVNGPLVILDDVKF--PKFAEIVTLTLQD-GSQRSGQVLEVSGSKAVVQVFEGTSGIDAkHTTCEFTG 99 689*************..**********99*.*****************************99******8 PP >> Rtf2 Rtf2 RING-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 4.9e-05 0.31 30 58 .. 88 116 .. 67 119 .. 0.86 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 4.9e-05 Rtf2 30 rkarwklCaLsqepLkkPivacrlGkLYn 58 a+ ++C+ + + L+ P+ ++ lG+ +n FUN_001483-T1 88 IDAKHTTCEFTGDILRTPVSSDMLGRVFN 116 56899***********************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (496 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 512 (0.0200431); expected 510.9 (0.02) Passed bias filter: 506 (0.0198082); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4738.64 // Query: FUN_001484-T1 [L=557] Description: FUN_001484 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-85 287.1 35.9 3.7e-85 286.5 35.9 1.3 1 CC149 Coiled-coil domain-containing protein 149-A ------ inclusion threshold ------ 0.018 15.6 4.2 0.018 15.6 4.2 5.3 5 TMF_TATA_bd TATA element modulatory factor 1 TATA binding 0.065 13.4 1.4 0.28 11.3 1.4 2.1 1 GlfT2_domain3 Galactofuranosyltransferase-2, domain 3 0.81 10.2 3.4 27 5.3 0.1 2.8 2 At4g15545_C At4g15545-like, C-terminal domain 1.3 8.3 39.2 0.071 12.5 27.9 2.8 2 CALCOCO1 Calcium binding and coiled-coil domain (CALCO 4.2 8.6 6.9 0.64 11.3 0.3 3.1 3 PDGF_N Platelet-derived growth factor, N terminal re Domain annotation for each model (and alignments): >> CC149 Coiled-coil domain-containing protein 149-A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 286.5 35.9 8.8e-89 3.7e-85 1 316 [] 21 359 .. 21 359 .. 0.90 Alignments for each domain: == domain 1 score: 286.5 bits; conditional E-value: 8.8e-89 CC149 1 krkLesKveALliLskeLekcrqerdqyklmaeqLqerlsalkkqleelkalsnslkee..........................keeqkklaell 70 k+kL+sK+eAL+iL +Le c++erd yk++++qL ++++ kk++ e++ l++ k+ +++qk+l+++l FUN_001484-T1 21 KKKLNSKREALKILTSDLELCQRERDIYKTKIKQLVKEVDDFKKKEIEQENLKQAQKPIsstpvkkrgssfsgnsvweqelqnvrERKQKTLSQML 116 89****************************************99998888887765554799***********************9********** PP CC149 71 eesreenkalkleveeLrqklkeaqgDiklLReeeqlarqklgakdedllstrhssadereelvkqlEklkkkkeqleldlksvldekeeleterd 166 +esr enkalk+++ eLrq +++ q+Di+lL +a+qk + ++++++ +d r++l++qlEk ++k+ +le+d +++ dek e++terd FUN_001484-T1 117 CESRAENKALKKDMAELRQLYRDSQEDIQLLH--DVMAKQKNR---SNSIKAGDGDLDPRQDLIAQLEKNQEKMMELERDKMAISDEKAEIATERD 207 ********************************..566666555...4567887888**************************************** PP CC149 167 aykeKaerLnheLsvlLkgdesrivDiDaLilENrYlkerlkqleeEkelikqtlskYksllekkknkgslklgensskesvlsakqvkelle... 259 +yk+K erLn++L+++L++d++r+vDiD++++ENrYlke++kql+eEk+++ ++l++Yk+++ek+knk + ++s + + + +ll+ FUN_001484-T1 208 HYKDKSERLNTQLNFILGADDRRLVDIDSVLMENRYLKEQIKQLKEEKNMAVSALARYKNIFEKRKNKILQAQLQGSYGN--TPRQAMPSLLSdli 301 *******************************************************************5333332333222..23333445555555 PP CC149 260 sglleatpqka.isdlkslataLlealndKnlaLsHqrktNkiLaarvaeLekklktl 316 ++l++ +p + +sdl++la++L e+l++K++aL+H r++NkiL++rvaeLekklktl FUN_001484-T1 302 GHLSSTSPATStVSDLQFLANSLSETLSEKDTALQHLRSANKILGHRVAELEKKLKTL 359 677777777766********************************************97 PP >> TMF_TATA_bd TATA element modulatory factor 1 TATA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 3.9 0.0091 39 25 74 .. 28 77 .. 13 85 .. 0.87 2 ? 15.6 4.2 4.2e-06 0.018 69 110 .. 97 139 .. 84 144 .. 0.89 3 ? 5.7 0.6 0.005 21 27 83 .. 177 219 .. 156 226 .. 0.56 4 ? 3.2 0.2 0.03 1.3e+02 27 54 .. 240 267 .. 233 289 .. 0.58 5 ? 0.0 0.1 0.29 1.2e+03 20 79 .. 327 355 .. 305 362 .. 0.51 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0091 TMF_TATA_bd 25 egElaslkeelarleaerdeareEivklmkeneelkelkkeleelekelk 74 l+ l ++l+ ++erd ++ i +l+ke+++ k+++ e e+l++ k FUN_001484-T1 28 REALKILTSDLELCQRERDIYKTKIKQLVKEVDDFKKKEIEQENLKQAQK 77 5557888999999********************************99765 PP == domain 2 score: 15.6 bits; conditional E-value: 4.2e-06 TMF_TATA_bd 69 lekelkeleeryettL.ellGEKsEeveELkaDveDlKelyre 110 e+el++++er ++tL ++l E e++ Lk+D+++l++lyr+ FUN_001484-T1 97 WEQELQNVRERKQKTLsQMLCESRAENKALKKDMAELRQLYRD 139 689*****9999888868***********************97 PP == domain 3 score: 5.7 bits; conditional E-value: 0.005 TMF_TATA_bd 27 ElaslkeelarleaerdeareEivklmkeneelkelkkeleelekelkeleeryett 83 +l++ +e++ +le+++ ++++E ++ +e + k++ +er++t FUN_001484-T1 177 QLEKNQEKMMELERDKMAISDEKAEIATERDHYKDK--------------SERLNTQ 219 333444444444444444444444444444444444..............4444444 PP == domain 4 score: 3.2 bits; conditional E-value: 0.03 TMF_TATA_bd 27 ElaslkeelarleaerdeareEivklmk 54 E + lke++++l++e++ a + + + + FUN_001484-T1 240 ENRYLKEQIKQLKEEKNMAVSALARYKN 267 4555566666666665555544444333 PP == domain 5 score: 0.0 bits; conditional E-value: 0.29 TMF_TATA_bd 20 eirrlegElaslkeelarleaerdeareEivklmkeneelkelkkeleelekelkeleer 79 ++ ++++ l++l+ + ++ l +++ele++ FUN_001484-T1 327 TLSEKDTALQHLR-------------------------------SANKILGHRVAELEKK 355 3333333333333...............................3333333444444444 PP >> GlfT2_domain3 Galactofuranosyltransferase-2, domain 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 1.4 6.7e-05 0.28 145 185 .. 104 144 .. 98 148 .. 0.94 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6.7e-05 GlfT2_domain3 145 frkRdrekakellkeslrlqkelarrfdelrkeYraalpeL 185 r R +++++++l es + +k l++ elr+ Yr++++++ FUN_001484-T1 104 VRERKQKTLSQMLCESRAENKALKKDMAELRQLYRDSQEDI 144 599*********************************99875 PP >> At4g15545_C At4g15545-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.7 0.015 62 26 57 .. 246 277 .. 241 283 .. 0.84 2 ? 5.3 0.1 0.0063 27 35 63 .. 331 359 .. 318 362 .. 0.85 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.015 At4g15545_C 26 aniKelNakrqsreeTLekaeeiFGeenkdLy 57 ++iK+l ++++ +L++ ++iF ++++++ FUN_001484-T1 246 EQIKQLKEEKNMAVSALARYKNIFEKRKNKIL 277 68**********************99887654 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0063 At4g15545_C 35 rqsreeTLekaeeiFGeenkdLyesFegl 63 + + + L++a++i+G++ ++L +++++l FUN_001484-T1 331 KDTALQHLRSANKILGHRVAELEKKLKTL 359 56777889***************999987 PP >> CALCOCO1 Calcium binding and coiled-coil domain (CALCOCO1) like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 8.6 1.8 7.5e+03 57 111 .. 41 94 .. 2 115 .. 0.42 2 ? 12.5 27.9 1.7e-05 0.071 54 242 .. 102 296 .. 94 366 .. 0.78 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 1.8 CALCOCO1 57 rekekeeykrdreelererkeLesrveelkeelkelrekveelekkqkelealse 111 ++e++ yk++ ++l +e+ +++++ e +e+lk++++ +++ k+++ + +++ FUN_001484-T1 41 CQRERDIYKTKIKQLVKEVDDFKKK-EIEQENLKQAQKPISSTPVKKRGSSFSGN 94 1222223333333333333333322.11233444444444444444444444444 PP == domain 2 score: 12.5 bits; conditional E-value: 1.7e-05 CALCOCO1 54 nrqrekekeeykrdreelererkeLesrveelkeelkelrekve...elekkqkeleal...seelaeekdalleqkeesearirELEeDiktltq 143 ++ re++++ + +e e k L+++++el++ + ++e+++ ++++kqk+ +++ ++ + ++ l++q e++++++ ELE D ++++ FUN_001484-T1 102 QNVRERKQKTLSQMLCESRAENKALKKDMAELRQLYRDSQEDIQllhDVMAKQKNRSNSikaGDGDLDPRQDLIAQLEKNQEKMMELERDKMAISD 197 4567888888888888888999999999999999999999987522255667776665411133344678899*********************** PP CALCOCO1 144 kalekEteLeRlkervkkalaqrkeeeaerkqlqakleqteeElrslskelqelrnslaqrdtsvlqLqdtittltqkLttAqrkeaenEalleel 239 + e te + k++ +++ +q+ +++++ E+r l +++++l++ ++ + + + ++ + ++k+ +Aq + + ++ + FUN_001484-T1 198 EKAEIATERDHYKDKSERLNTQLNFILGADDRRLVDIDSVLMENRYLKEQIKQLKEEKNMAVSALARYKNIFEKRKNKILQAQLQGSYGNTPRQAM 293 **********************99876555555568*******************************************99998776666666666 PP CALCOCO1 240 rsl 242 sl FUN_001484-T1 294 PSL 296 665 PP >> PDGF_N Platelet-derived growth factor, N terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.3 0.00015 0.64 23 69 .. 227 274 .. 225 280 .. 0.74 2 ? -3.1 0.1 4.4 1.9e+04 19 27 .. 312 320 .. 298 345 .. 0.59 3 ? -3.1 0.2 4.6 2e+04 31 58 .. 526 535 .. 507 550 .. 0.48 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00015 PDGF_N 23 dLqRlLeidsvdeedeeneetklrahksvssssadlkr.eklhsRrkr 69 d +Rl +idsv e+ +e++++ +++++ ++l r ++ +rk FUN_001484-T1 227 DDRRLVDIDSVLMENRYLKEQIKQLKEEKNMAVSALARyKNIFEKRKN 274 559******************999998888777666541444444555 PP == domain 2 score: -3.1 bits; conditional E-value: 4.4 PDGF_N 19 rSisdLqRl 27 +sdLq l FUN_001484-T1 312 STVSDLQFL 320 347888765 PP == domain 3 score: -3.1 bits; conditional E-value: 4.6 PDGF_N 31 dsvdeedeeneetklrahksvssssadl 58 +sv++ + + FUN_001484-T1 526 ESVVDSNC------------------NN 535 33333333..................22 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (557 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2444 (0.0956743); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 30 (0.0011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.41 # Mc/sec: 5411.99 // Query: FUN_001485-T1 [L=332] Description: FUN_001485 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-30 104.5 20.9 2.4e-19 70.3 5.4 2.1 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.5e-07 32.0 16.9 4.8e-05 23.8 16.9 2.7 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 6.2 6.8 11.9 0.96 9.4 1.3 2.6 3 Vac14_Fig4_bd Vacuolar protein 14 C-terminal Fig4p binding Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.3 5.4 2.9e-23 2.4e-19 2 140 .. 58 198 .. 57 201 .. 0.88 2 ! 41.0 10.8 2.5e-14 2.2e-10 161 260 .] 192 299 .. 185 299 .. 0.81 Alignments for each domain: == domain 1 score: 70.3 bits; conditional E-value: 2.9e-23 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevl..Cklvtaldvv...nltasillltaisiDRYlaIvkplk 92 Nll++l+i r+ l++p+n +l+ La++Dl v+++v p+ +++ l ++ +g+ + C++ +a+ v+ +++ s+l++ta+s+DRYla+ +l+ FUN_001485-T1 58 NLLILLTIRRTVTLHSPSNALLFGLALSDLGVGVIVQPLYFAHML---GKLIGDKGsfCHAGIAIEVCanaLCIISLLTVTAVSVDRYLALKLHLR 150 9**************************************998888...34443332228876666554222799********************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvCli 140 y+++ t rr++++ +++W+++++++ ++l+ ++ ++s + + t+Cl+ FUN_001485-T1 151 YNELITIRRVTFVNAIIWIVGAAIGSMWLYEPDWVKFSVSATITICLL 198 *************************************9999****986 PP == domain 2 score: 41.0 bits; conditional E-value: 2.5e-14 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 161 gfllpllvilvcyvrilrtlrksakkeks........kkkksarker...........kalktllvvvvvfvlcwlPyfilllldsllkecesekl 237 + + ll ++cy++i+r ++++ ++ r + ++ v ++f++c++Pyf+++++ s+ +e + + FUN_001485-T1 192 TITICLLAAAYCYAKIYRVVSRHYRNDMAlrsavneaD--------RvehsinmlkfkSHAISTFWVYCLFIVCYFPYFCVVIVISF---SELSVT 276 455679999**************999988555554440........24444555555577777888999******************...****** PP xxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 238 vetallitlllayvnsclNPiiY 260 + +++it l++++ns lNP++Y FUN_001485-T1 277 KRFFYEITALIIFINSFLNPVVY 299 **********************9 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 16.9 5.6e-09 4.8e-05 8 273 .. 54 310 .. 48 316 .. 0.76 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 5.6e-09 7tm_4 8 illGnltilfvikteaslhqPmylflallalidlglsastlP....tvlGiflvdareisfeacllqlffihkfsllesavllamavdrfvaiysp 99 +++ nl il i+ +lh P +l lal dlg+ + P ++lG l++ + + +a ++ + ++ ++ ++ a++vdr+ a+ + FUN_001485-T1 54 TVIFNLLILLTIRRTVTLHSPSNALLFGLALSDLGVGVIVQPlyfaHMLGK-LIGDKGSFCHAGIAIEVCANALCIISLLTVTAVSVDRYLALKLH 148 56779*******************************999887333357775.678888899999999999************************** PP 7tm_4 100 lryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsyglilrtv 195 lry e+ t ++++ + ++++ + + + + + + s + l+ a +iy + vs + +++ + r FUN_001485-T1 149 LRYNELITIRRVTFVNAIIWIVGAA--------IGSMWLYEPDWVKFSVSATITICLLAAAY-CYAKIYRV---VSRHYRNDMALRSAVNEADRVE 232 ************9999999987777........33333444444555544444555555443.44567765...6666666667777777777777 PP 7tm_4 196 lgiasreerkkalntcgshvcavlafyvPmiglsvvhrfgk.kvsrllqvllanlyllfPPvlnPivysvktkeirdav 273 +i + + a++t + + ++ y P + +v f++ v++ ++ l +++ lnP+vy + ++ir+ v FUN_001485-T1 233 HSINMLKFKSHAISTFWVYCLF-IVCYFPYFCVVIVISFSElSVTKRFFYEITALIIFINSFLNPVVYCWRLQDIRHGV 310 8888888888888887766444.44566777777777776536777777778888888888888888888888888766 PP >> Vac14_Fig4_bd Vacuolar protein 14 C-terminal Fig4p binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 0.76 6.5e+03 85 103 .. 122 135 .. 112 161 .. 0.58 2 ? 5.1 0.6 0.0025 21 84 116 .. 184 219 .. 177 231 .. 0.69 3 ? 9.4 1.3 0.00011 0.96 78 142 .. 237 304 .. 212 312 .. 0.69 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 0.76 Vac14_Fig4_bd 85 chnpvaalsLcLlaqayel 103 c n+++++sL FUN_001485-T1 122 CANALCIISLLT-----VT 135 444444444433.....33 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0025 Vac14_Fig4_bd 84 wch.npvaalsLcLlaqayela..yeliqslaelev 116 w + + a++++cLla ay a y++++ ++ FUN_001485-T1 184 WVKfSVSATITICLLAAAYCYAkiYRVVSRHYRNDM 219 554144579********9876633677766666555 PP == domain 3 score: 9.4 bits; conditional E-value: 0.00011 Vac14_Fig4_bd 78 salykswchnpvaalsLcLlaqayelayeliqslaelevtvellvqldkLvqllEs...pvftklRlq 142 + +ks + ++ + +L +++ +++ ++ s++el+vt +++ ++ L+ ++ s pv Rlq FUN_001485-T1 237 MLKFKSHAISTFWVYCLFIVCYFPYFCVVIVISFSELSVTKRFFYEITALIIFINSflnPVVYCWRLQ 304 33355555555555555555555568889999*********************998555677777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1271 (0.0497553); expected 510.9 (0.02) Passed bias filter: 545 (0.0213349); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3369.41 // Query: FUN_001486-T1 [L=89] Description: FUN_001486 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (89 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 399 (0.0156195); expected 510.9 (0.02) Passed bias filter: 304 (0.0119006); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.36s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 932.86 // Query: FUN_001487-T1 [L=105] Description: FUN_001487 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-11 43.0 1.6 1e-10 42.6 1.6 1.1 1 THAP THAP domain Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.6 1.6 4e-15 1e-10 1 85 [. 6 85 .. 6 86 .. 0.79 Alignments for each domain: == domain 1 score: 42.6 bits; conditional E-value: 4e-15 THAP 1 CavpgCknkskskskkkvsfhrfPkdkerrkkWlknikredlekkkk.kksrvCskHFeeelekeedeekrskkrrrLkpdavPtl 85 C+v++C+nk s+++ +s+h Pk + ++kW +++ ++ + +++ + ++Cs HF++++ k + +++ rrL +++Pt+ FUN_001487-T1 6 CVVQDCSNK--SNPRIGISLH-TPKYNYELAKWKSFVRTHSSNFNPNgR-FKICSVHFSSDCFK--WTVHKEGAPRRLITGSIPTI 85 ********4..4455669***.699999*********999888777743.69******999444..23445566667********8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (105 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 414 (0.0162067); expected 510.9 (0.02) Passed bias filter: 276 (0.0108045); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1072.63 // Query: FUN_001488-T1 [L=235] Description: FUN_001488 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-13 51.4 3.6 7.2e-13 49.9 3.6 1.7 1 CAP Cysteine-rich secretory protein family Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.9 3.6 2.8e-17 7.2e-13 3 112 .. 33 141 .. 31 147 .. 0.80 Alignments for each domain: == domain 1 score: 49.9 bits; conditional E-value: 2.8e-17 CAP 3 lhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hrtn 91 hN++R+ +++pp++w+ L + A++++k++aen+ ++h++ + gn++ + e da+ + e+++yny+++ ++++ FUN_001488-T1 33 WHNYFRTLHQVPPVTWSMGLQKEAEAWVKYLAENNKFQHSQHNRGNLFITEHIPK--------EYCSDAIWWFHWEEKHYNYSDPryirragNFSQ 120 59********************************977777666666554444444........457777744466777888888888999****** PP CAP 92 llwpkstkvGcavakcgdgsy 112 ++w++st++G a+a +dg+ FUN_001488-T1 121 VVWKNSTQIGAAWAIRKDGKL 141 *************99988865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (235 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 728 (0.0284987); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2364.81 // Query: FUN_001488-T2 [L=212] Description: FUN_001488 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-13 52.0 3.4 4.8e-13 50.5 3.4 1.7 1 CAP Cysteine-rich secretory protein family Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.5 3.4 1.9e-17 4.8e-13 3 112 .. 10 118 .. 8 124 .. 0.80 Alignments for each domain: == domain 1 score: 50.5 bits; conditional E-value: 1.9e-17 CAP 3 lhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hrtn 91 hN++R+ +++pp++w+ L + A++++k++aen+ ++h++ + gn++ + e da+ + e+++yny+++ ++++ FUN_001488-T2 10 WHNYFRTLHQVPPVTWSMGLQKEAEAWVKYLAENNKFQHSQHNRGNLFITEHIPK--------EYCSDAIWWFHWEEKHYNYSDPryirragNFSQ 97 59********************************977777666666554444444........457777744466777888888888999****** PP CAP 92 llwpkstkvGcavakcgdgsy 112 ++w++st++G a+a +dg+ FUN_001488-T2 98 VVWKNSTQIGAAWAIRKDGKL 118 *************99988865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (212 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 811 (0.0317479); expected 510.9 (0.02) Passed bias filter: 650 (0.0254453); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.34s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 2164.39 // Query: FUN_001488-T3 [L=212] Description: FUN_001488 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-13 52.0 3.4 4.8e-13 50.5 3.4 1.7 1 CAP Cysteine-rich secretory protein family Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.5 3.4 1.9e-17 4.8e-13 3 112 .. 10 118 .. 8 124 .. 0.80 Alignments for each domain: == domain 1 score: 50.5 bits; conditional E-value: 1.9e-17 CAP 3 lhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hrtn 91 hN++R+ +++pp++w+ L + A++++k++aen+ ++h++ + gn++ + e da+ + e+++yny+++ ++++ FUN_001488-T3 10 WHNYFRTLHQVPPVTWSMGLQKEAEAWVKYLAENNKFQHSQHNRGNLFITEHIPK--------EYCSDAIWWFHWEEKHYNYSDPryirragNFSQ 97 59********************************977777666666554444444........457777744466777888888888999****** PP CAP 92 llwpkstkvGcavakcgdgsy 112 ++w++st++G a+a +dg+ FUN_001488-T3 98 VVWKNSTQIGAAWAIRKDGKL 118 *************99988865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (212 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 818 (0.0320219); expected 510.9 (0.02) Passed bias filter: 659 (0.0257976); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 2169.06 // Query: FUN_001489-T1 [L=183] Description: FUN_001489 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-12 48.7 1.5 3.7e-12 47.6 1.5 1.5 1 CAP Cysteine-rich secretory protein family ------ inclusion threshold ------ 0.095 13.3 0.1 0.19 12.4 0.1 1.4 1 DUF7214 Domain of unknown function (DUF7214) Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.6 1.5 2.9e-16 3.7e-12 12 112 .. 3 102 .. 1 108 [. 0.72 Alignments for each domain: == domain 1 score: 47.6 bits; conditional E-value: 2.9e-16 CAP 12 glppLswdaeLaaaAqehaktcaeng..shnhrsptggnilarvaaagreniaageesaedavk..gWydepgtynygaa.......hrtnllwpk 96 +pp++w+ +L + A+e++k++aen+ +h+++ p + + +++ +++ da+ +W +e+ y+y+++ h+++++w++ FUN_001489-T1 3 TVPPVTWSMDLQKEAEEWVKYLAENNkyHHSPHNPGNLYLQGQIPKEY----------CSDAIWwfHWEEEK--YDYSKPryspstgHFSQVVWRN 86 689**********************99555555555555555555555..........45555200444444..5555555599999********* PP CAP 97 stkvGcavakcgdgsy 112 s+++G a+a +dg+ FUN_001489-T1 87 SKEIGAAWALRKDGKL 102 ********99988865 PP >> DUF7214 Domain of unknown function (DUF7214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 1.5e-05 0.19 57 78 .. 6 26 .. 2 29 .. 0.86 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.5e-05 DUF7214 57 pvtyprvdtaadaetwvrylae 78 pvt+ +d +++ae+wv+ylae FUN_001489-T1 6 PVTW-SMDLQKEAEEWVKYLAE 26 7777.4899************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (183 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 615 (0.0240752); expected 510.9 (0.02) Passed bias filter: 492 (0.0192601); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1824.03 // Query: FUN_001491-T1 [L=104] Description: FUN_001491 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 381 (0.0149149); expected 510.9 (0.02) Passed bias filter: 359 (0.0140536); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1044.40 // Query: FUN_001492-T1 [L=162] Description: FUN_001492 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-10 40.1 1.3 1.3e-09 39.5 1.3 1.4 1 CAP Cysteine-rich secretory protein family Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.5 1.3 4.9e-14 1.3e-09 2 91 .. 36 124 .. 35 141 .. 0.93 Alignments for each domain: == domain 1 score: 39.5 bits; conditional E-value: 4.9e-14 CAP 2 dlhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hrt 90 + hN++R+ ++++ ++w+++L +A+++a+++a+ + ++h++++ gn++ ++++ + + avk +y e+++yny+++ h+t FUN_001492-T1 36 EWHNYYRRIHQVANVTWSDNLWLQAKTWAEYLAKENKFQHEPKQPGNLFLSPGQPI--------DPCATAVKYFYMEEKYYNYSNPhfslrtgHFT 123 66***********************************************9999999........999*******999*********8888888877 PP CAP 91 n 91 + FUN_001492-T1 124 Q 124 7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (162 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 745 (0.0291642); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1643.12 // Query: FUN_001493-T1 [L=918] Description: FUN_001493 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-30 104.5 0.3 4.5e-09 36.6 0.0 6.3 6 Ank Ankyrin repeat 4.5e-28 98.1 0.0 4.1e-14 53.4 0.0 3.2 3 Ank_2 Ankyrin repeats (3 copies) 1.9e-23 82.5 0.2 9.6e-08 32.6 0.0 5.7 6 Ank_4 Ankyrin repeats (many copies) 2.8e-22 79.0 0.2 5.3e-07 30.4 0.0 4.8 5 Ank_5 Ankyrin repeats (many copies) 3.5e-19 67.1 0.0 8.6e-06 26.2 0.0 6.3 6 Ank_3 Ankyrin repeat 3e-18 66.4 9.6 5.4e-18 65.5 9.6 1.4 1 Ion_trans Ion transport protein 3.8e-11 43.3 3.6 1.8e-09 37.8 0.5 2.5 2 PKD_channel Polycystin cation channel ------ inclusion threshold ------ 0.018 16.0 3.3 0.022 15.7 0.8 2.5 2 Snapin_Pallidin Snapin/Pallidin 0.02 15.3 0.0 1.2 9.5 0.0 2.4 3 ANK_LRRK2 LRRK2 ANK repeat 1.1 9.8 11.8 0.075 13.5 2.7 3.1 3 TMF_DNA_bd TATA element modulatory factor 1 DNA binding 1.9 9.2 11.0 0.3 11.8 3.1 2.4 2 DUF4530 Domain of unknown function (DUF4530) Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.11 2.5e+02 18 32 .. 215 229 .. 191 230 .. 0.87 2 ! 17.1 0.0 3.1e-06 0.0071 1 32 [. 231 262 .. 231 263 .. 0.92 3 ! 36.6 0.0 1.9e-12 4.5e-09 1 32 [. 264 295 .. 264 296 .. 0.95 4 ! 21.8 0.0 9.8e-08 0.00023 3 32 .. 300 329 .. 298 330 .. 0.92 5 ! 17.8 0.0 1.9e-06 0.0044 3 32 .. 333 362 .. 331 363 .. 0.90 6 ? -0.7 0.0 1.4 3.4e+03 4 19 .. 419 434 .. 419 435 .. 0.88 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.11 Ank 18 vklLLkhGAdvnard 32 ++ LL++GA+vn+ d FUN_001493-T1 215 IQSLLNDGASVNVSD 229 6779*88*****998 PP == domain 2 score: 17.1 bits; conditional E-value: 3.1e-06 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G+T LH +r +ev+++L+++GAd+n d FUN_001493-T1 231 YGQTLLHEVSRTWGIEVAQFLIDQGADINKHD 262 69******9999**********88*****987 PP == domain 3 score: 36.6 bits; conditional E-value: 1.9e-12 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G+TPLH+Aa+++++e+v++L+++GA+v+ar+ FUN_001493-T1 264 YGRTPLHVAASEDYPEMVRFLIEKGANVHART 295 69********************88******97 PP == domain 4 score: 21.8 bits; conditional E-value: 9.8e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 ++PL++A+++ +++vk+LL +GAd+ ard FUN_001493-T1 300 QSPLYYASKNEAVDCVKILLAYGADMEARD 329 79******9999********77******99 PP == domain 5 score: 17.8 bits; conditional E-value: 1.9e-06 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPL++Aa++++ ev +lLL++GA+ ++d FUN_001493-T1 333 RTPLYVAAEHKSAEVTRLLLDAGASAGVKD 362 8*******99**********88**988877 PP == domain 6 score: -0.7 bits; conditional E-value: 1.4 Ank 4 TPLHlAaraghlevvk 19 +PL +A+ ++l++vk FUN_001493-T1 419 SPLQAASLSNCLDLVK 434 69*****889999998 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.4 0.0 1.8e-17 4.1e-14 13 89 .. 215 294 .. 204 295 .. 0.92 2 ! 41.1 0.0 1.2e-13 2.9e-10 28 90 .] 298 362 .. 293 362 .. 0.91 3 ? -2.2 0.0 3.8 8.8e+03 62 77 .. 419 434 .. 401 435 .. 0.68 Alignments for each domain: == domain 1 score: 53.4 bits; conditional E-value: 1.8e-17 Ank_2 13 vklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 ++ Ll ga++n+ d g+t Lh ++ +e++++L+++gad+n d++grt+Lh+Aa++++ e+v++L+ekga+++a+ FUN_001493-T1 215 IQSLLnDGASVNVSDRYGQTLLHEVSRTWGIEVAQFLIDQGADINkhDDYGRTPLHVAASEDYPEMVRFLIEKGANVHAR 294 788998999***9999*******88887668************99999****************************9876 PP == domain 2 score: 41.1 bits; conditional E-value: 1.2e-13 Ank_2 28 ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 + +++L++A kn +++vk+Ll++gad + d + rt+L++Aae+++ e+ +lLl+ ga+ +kd FUN_001493-T1 298 EDQSPLYYASKNEAVDCVKILLAYGADMEarDYKLRTPLYVAAEHKSAEVTRLLLDAGASAGVKD 362 4589********************9887777999*********************99*9988876 PP == domain 3 score: -2.2 bits; conditional E-value: 3.8 Ank_2 62 taLhyAaesghleivk 77 ++L+ A+ s++l+ vk FUN_001493-T1 419 SPLQAASLSNCLDLVK 434 4677777777777665 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 5.3e-05 0.12 12 38 .. 214 240 .. 182 242 .. 0.88 2 ! 32.6 0.0 4.1e-11 9.6e-08 10 50 .] 245 285 .. 244 285 .. 0.97 3 ! 31.5 0.0 8.9e-11 2.1e-07 2 50 .] 270 319 .. 270 319 .. 0.97 4 ! 23.9 0.0 2.3e-08 5.3e-05 1 50 [] 303 352 .. 303 352 .. 0.96 5 ! 9.2 0.0 0.00098 2.3 1 34 [. 336 369 .. 336 371 .. 0.94 6 ? -2.9 0.0 6.5 1.5e+04 3 14 .. 423 434 .. 421 434 .. 0.72 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 5.3e-05 Ank_4 12 llklLlengadinatdgngetaLhfAa 38 +++Ll+ ga++n +d++g+t Lh ++ FUN_001493-T1 214 YIQSLLNDGASVNVSDRYGQTLLHEVS 240 499*********************876 PP == domain 2 score: 32.6 bits; conditional E-value: 4.1e-11 Ank_4 10 lellklLlengadinatdgngetaLhfAasngnlevlklLl 50 +e++++L++ gadin+ d++g+t+Lh Aas ++e++++L+ FUN_001493-T1 245 IEVAQFLIDQGADINKHDDYGRTPLHVAASEDYPEMVRFLI 285 5899************************************8 PP == domain 3 score: 31.5 bits; conditional E-value: 8.9e-11 Ank_4 2 haAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 h+Aa++ e++++L+e+ga+++a+ g+++++L++A++n+ ++++k Ll FUN_001493-T1 270 HVAASEDYPEMVRFLIEKGANVHARtAGEDQSPLYYASKNEAVDCVKILL 319 89***********************9899******************997 PP == domain 4 score: 23.9 bits; conditional E-value: 2.3e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 l +A k + ++++k Ll++gad+ a+d+ +t+L+ Aa + + ev +lLl FUN_001493-T1 303 LYYASKNEAVDCVKILLAYGADMEARDYKLRTPLYVAAEHKSAEVTRLLL 352 679999*****************************************997 PP == domain 5 score: 9.2 bits; conditional E-value: 0.00098 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaL 34 l +Aa++ e+ +lLl+ ga+ d+ng++aL FUN_001493-T1 336 LYVAAEHKSAEVTRLLLDAGASAGVKDDNGMSAL 369 5689999*************************98 PP == domain 6 score: -2.9 bits; conditional E-value: 6.5 Ank_4 3 aAaksghlellk 14 aA s++l+l+k FUN_001493-T1 423 AASLSNCLDLVK 434 4555*****997 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 3.6e-05 0.084 1 49 [. 218 265 .. 218 265 .. 0.95 2 ! 30.4 0.0 2.3e-10 5.3e-07 1 47 [. 251 296 .. 251 300 .. 0.93 3 ! 15.0 0.0 1.5e-05 0.035 13 45 .. 296 328 .. 294 329 .. 0.87 4 ! 23.2 0.0 3.9e-08 9.1e-05 12 54 .. 328 370 .. 324 372 .. 0.90 5 ? -3.3 0.0 8.2 1.9e+04 10 29 .. 641 660 .. 640 663 .. 0.82 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 3.6e-05 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeeg 49 Ll+ g a++n +d++g+t Lh +++ e++++L++ g+d+n +d++g FUN_001493-T1 218 LLNDG-ASVNVSDRYGQTLLHEVSRTWGIEVAQFLIDQGADINKHDDYG 265 77888.9************************************999987 PP == domain 2 score: 30.4 bits; conditional E-value: 2.3e-10 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkde 47 L++ g ad+n d++g tpLhvAa+ +++e+vr+L++ g++++++++ FUN_001493-T1 251 LIDQG-ADINKHDDYGRTPLHVAASEDYPEMVRFLIEKGANVHARTA 296 78889.*********************************99999986 PP == domain 3 score: 15.0 bits; conditional E-value: 1.5e-05 Ank_5 13 dgegytpLhvAakygaleivrlLlangvdlnlk 45 ge + pL +A+k+ a ++v++Lla+g+d ++ FUN_001493-T1 296 AGEDQSPLYYASKNEAVDCVKILLAYGADMEAR 328 567789**********************97666 PP == domain 4 score: 23.2 bits; conditional E-value: 3.9e-08 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpld 54 +d + tpL vAa+++++e+ rlLl+ g+++++kd++g ++l FUN_001493-T1 328 RDYKLRTPLYVAAEHKSAEVTRLLLDAGASAGVKDDNGMSALS 370 677888********************************88875 PP == domain 5 score: -3.3 bits; conditional E-value: 8.2 Ank_5 10 nrldgegytpLhvAakygal 29 +++ ++ + +L + + yga+ FUN_001493-T1 641 DDTSKWLFVILVFYIPYGAA 660 5778899999*******997 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 6.9 1.6e+04 17 31 .] 214 227 .. 211 227 .. 0.83 2 ! 10.1 0.0 0.00069 1.6 1 30 [. 231 259 .. 231 260 .. 0.95 3 ! 26.2 0.0 3.7e-09 8.6e-06 1 30 [. 264 292 .. 264 293 .. 0.96 4 ! 11.1 0.0 0.00032 0.75 3 28 .. 300 324 .. 298 326 .. 0.95 5 ! 10.6 0.0 0.00044 1 3 28 .. 333 357 .. 331 360 .. 0.90 6 ? -0.3 0.0 1.6 3.8e+03 4 19 .. 419 434 .. 419 443 .. 0.90 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 6.9 Ank_3 17 ivklLleklgadina 31 +++ Ll+ ga++n+ FUN_001493-T1 214 YIQSLLN-DGASVNV 227 58899**.9**9995 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00069 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+t+Lh + r +e++++L++ +gadin FUN_001493-T1 231 YGQTLLHEVSRTWGIEVAQFLID-QGADIN 259 79*****9999999*********.*****9 PP == domain 3 score: 26.2 bits; conditional E-value: 3.7e-09 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+tpLh+Aa+ + +e+v++L+e +ga+++ FUN_001493-T1 264 YGRTPLHVAASEDYPEMVRFLIE-KGANVH 292 79*********************.****98 PP == domain 4 score: 11.1 bits; conditional E-value: 0.00032 Ank_3 3 ntpLhlAarngrleivklLleklgad 28 ++pL++A +n ++ vk Ll +gad FUN_001493-T1 300 QSPLYYASKNEAVDCVKILLA-YGAD 324 89*******************.**98 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00044 Ank_3 3 ntpLhlAarngrleivklLleklgad 28 +tpL++Aa++ + e+ +lLl+ ga+ FUN_001493-T1 333 RTPLYVAAEHKSAEVTRLLLD-AGAS 357 8********************.8876 PP == domain 6 score: -0.3 bits; conditional E-value: 1.6 Ank_3 4 tpLhlAarngrleivk 19 +pL A ++++l++vk FUN_001493-T1 419 SPLQAASLSNCLDLVK 434 69999*******9987 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.5 9.6 2.3e-21 5.4e-18 10 242 .. 463 742 .. 453 743 .. 0.79 Alignments for each domain: == domain 1 score: 65.5 bits; conditional E-value: 2.3e-21 Ion_trans 10 llillntvvlal....etyfqpeekel...klleildlvftviftlemllkiialgl....................................... 59 l+il++++++ + + + ++++i+ ++ +++l+ + k + ++ FUN_001493-T1 463 LTILYTVFACSMprdvSAFY---T--PlsqQWWKIVIEIVFLLIMLDEIRKEVKEYYrskkqsrklikwrrreverdsafchprwpqeksfveqel 553 44444444444432211112...2..1235788888444444455555666666666689999999999999999999999999999999999999 PP Ion_trans 60 .........kkkYlrspwnilDfvvvlpslislil.......ses..k.eslsllrvlrll.rllrllrlirrleglrtlvnslirslksllnlll 135 k+ Yl++pwn++D++ + ++++ ++l + + + + + ++ + +++ ++rll+++r ++g +v +l++++ + + l+ FUN_001493-T1 554 rmikqdkgnKQIYLSDPWNLFDWLTYAMLMVVIALhfvtvniK-NekYdRVFVGILSCSVIpVWVRLLKYARPFPGQGPFVVMLGHIIDDTSKWLF 648 999999999999*******************999998765542.14525777777777778789******************************** PP Ion_trans 136 llllvlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliavi 231 ++l++ + ++ + +f ++ + +d++++ +++++++ ++++ + ld+ + ++ i+ ++fii+++++l+nl+ia++ FUN_001493-T1 649 VILVFYIPYGAALWVMF----------GPRAQTPVQGYDTVFSLFYSILRIPLLDNYNF---NELDKAAPYMSRILCGSFIIIAAIVLMNLYIALL 731 *****************..........5667788999*************999996664...333333477899********************** PP Ion_trans 232 idnfqeltera 242 +++fq+++++a FUN_001493-T1 732 SNTFQRVYDNA 742 ******99875 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.2 0.0033 7.6 24 68 .. 548 595 .. 547 604 .. 0.78 2 ! 37.8 0.5 7.8e-13 1.8e-09 93 225 .] 601 738 .. 596 738 .. 0.89 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0033 PKD_channel 24 fvveeilkirker...asylrsvwnlldlaivvlsvvlivlailrevl 68 fv +e+ i++++ + yl++ wnl d + +++ +v+i l+++ ++ FUN_001493-T1 548 FVEQELRMIKQDKgnkQIYLSDPWNLFDWLTYAMLMVVIALHFVTVNI 595 5666666677665444789********************999987665 PP == domain 2 score: 37.8 bits; conditional E-value: 7.8e-13 PKD_channel 93 dqllriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtqasnfsnlvksiltl....frl.ilgdfq 183 d ++ il + v+ ++++llk+ r ++ + l ++d +vi+++ + y++++ ++fG a++ + + +++ l +r+ +l++ + FUN_001493-T1 601 DRVFVGILSCSVIPVWVRLLKYARPFPGQGPFVVMLGHIIDDTSKWLFVILVFYIPYGAALWVMFGPRAQTPVQGYDTVFSLfysiLRIpLLDNYN 696 67888999**********************************************************998876666666666622225544789*** PP PKD_channel 184 ytelesgnrvLGpllllalvflvifillnlflaiindsyeev 225 ++el+++ ++ +l+ +++++ +++l+nl +a++ ++++ v FUN_001493-T1 697 FNELDKAAPYMSRILCGSFIIIAAIVLMNLYIALLSNTFQRV 738 *************************************99865 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.1 3.2 7.4e+03 43 61 .. 754 770 .. 728 775 .. 0.54 2 ? 15.7 0.8 9.7e-06 0.022 12 52 .. 823 864 .. 816 895 .. 0.84 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 3.2 Snapin_Pallidin 43 Lqeleelqeevlpdlkeya 61 Lq+le +++ + +lk+y+ FUN_001493-T1 754 LQDLELDAS--MKKLKQYR 770 222222222..55555554 PP == domain 2 score: 15.7 bits; conditional E-value: 9.7e-06 Snapin_Pallidin 12 epklkeldeklkelrqsQeeLleqidrlaeeLqeleelqe.e 52 +++++++ e+l++l ++Q eL+ ++ +l+++L+el+++ + FUN_001493-T1 823 KSDIDAVLENLESLARNQLELRRSLCSLSSNLEELKNTMSfL 864 789********************************9998842 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.0 0.00051 1.2 31 89 .. 232 290 .. 222 296 .. 0.87 2 ? 8.1 0.0 0.0014 3.2 35 113 .. 269 352 .. 260 356 .. 0.77 3 ? 2.1 0.0 0.096 2.2e+02 38 88 .. 306 356 .. 296 379 .. 0.63 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00051 ANK_LRRK2 31 keklLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvr 89 ++lL+++ + +a l+ gad+nk+ + +v ++ +e+v l+++g++ FUN_001493-T1 232 GQTLLHEVSRTWGIEVAQFLIDQGADINKHDDYGRTPLHVAASEDYPEMVRFLIEKGAN 290 567888888899999****************99999999****************9975 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0014 ANK_LRRK2 35 LekaCeegdvvmaEcllllgadvnkkt..ktesliyqvCErgsplelvelllssgv....rEqdlrkaLavsvkrgdgevvsllL 113 L+ a +e+ m+ l++ ga+v +t +++s +y +++ ++ v++ll+ g+ r+ +lr+ L v+ +++ ev llL FUN_001493-T1 269 LHVAASEDYPEMVRFLIEKGANVHARTagEDQSPLYYA-SKNEAVDCVKILLAYGAdmeaRDYKLRTPLYVAAEHKSAEVTRLLL 352 667778888899***********988733345556654.67788********998532227889************999999998 PP == domain 3 score: 2.1 bits; conditional E-value: 0.096 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkkt.ktesliyqvCErgsplelvelllssgv 88 a +++ v + ll gad++ + k + +y E++ ++e+ lll+ g+ FUN_001493-T1 306 ASKNEAVDCVKILLAYGADMEARDyKLRTPLYVAAEHK-SAEVTRLLLDAGA 356 55556666677777777777655413444445444444.4677777776654 PP >> TMF_DNA_bd TATA element modulatory factor 1 DNA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.1 0.82 1.9e+03 27 41 .. 755 769 .. 751 772 .. 0.86 2 ? 0.1 0.2 0.49 1.1e+03 14 34 .. 785 805 .. 782 811 .. 0.68 3 ? 13.5 2.7 3.2e-05 0.075 13 71 .. 825 883 .. 818 886 .. 0.89 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.82 TMF_DNA_bd 27 kelklnntikkLrkk 41 ++l+l +++kkL++ FUN_001493-T1 755 QDLELDASMKKLKQY 769 7899999*****985 PP == domain 2 score: 0.1 bits; conditional E-value: 0.49 TMF_DNA_bd 14 IaqLmeEGekLskkelklnnt 34 Ia L eE e+ +k+e k +++ FUN_001493-T1 785 IAVLSEEDEQNRKQEEKVSEI 805 666777777777777665554 PP == domain 3 score: 13.5 bits; conditional E-value: 3.2e-05 TMF_DNA_bd 13 qIaqLmeEGekLskkelklnntikkLrkknkeleksvkelkkkleklekeleeleerlk 71 I++ +e++e L++++l+l+ ++ +L + ++el ++++ l+++ + ++e +++e + FUN_001493-T1 825 DIDAVLENLESLARNQLELRRSLCSLSSNLEELKNTMSFLSEERMRDNQERVQQKETFE 883 5****************************************999999999888887765 PP >> DUF4530 Domain of unknown function (DUF4530) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 1.0 0.2 4.6e+02 85 106 .. 783 804 .. 779 811 .. 0.82 2 ? 11.8 3.1 0.00013 0.3 53 106 .. 828 880 .. 820 886 .. 0.81 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.2 DUF4530 85 elvtileeeeeeeeeeeeeeee 106 + +++l ee+e+++++ee+ e FUN_001493-T1 783 DYIAVLSEEDEQNRKQEEKVSE 804 56799*9**9999999998666 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00013 DUF4530 53 wiweelgnlrrvdvqllgqlcslglemgalreelvtileeeeeeeeeeeeeeee 106 + e+l+ l r + l lcsl+ +++ l++ + ++l ee +++e+ +++e FUN_001493-T1 828 AVLENLESLARNQLELRRSLCSLSSNLEELKNTM-SFLSEERMRDNQERVQQKE 880 57899**************************996.6777777666666665555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (918 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1445 (0.0565668); expected 510.9 (0.02) Passed bias filter: 725 (0.0283813); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.47u 0.36s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 8663.65 // Query: FUN_001494-T1 [L=238] Description: FUN_001494 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-07 31.7 1.6 2.2e-07 31.2 1.6 1.1 1 CaKB Calcium-activated potassium channel, beta subunit Domain annotation for each model (and alignments): >> CaKB Calcium-activated potassium channel, beta subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.2 1.6 8.4e-12 2.2e-07 17 167 .. 26 178 .. 22 203 .. 0.67 Alignments for each domain: == domain 1 score: 31.2 bits; conditional E-value: 8.4e-12 CaKB 17 miafsvlmyfvlGitvlkpylksvwteeanCtvleveile....evvdcsfsc.gadcrkvskyPCLqvlvnlsssgkkalLhydeetlelnpkCf 107 ++ ++++ + + + l p l+s++ +C+v +++ ++ + + c s +a+++ + yPC+q++v+ s+ + + L + ++ ++ C+ FUN_001494-T1 26 LVCCGIVLLLEMILVAL-PKLESMQYWIGTCNVRNMKLNKaaggKQLRCHCSGhNANTKCTIYYPCIQIFVSFSHDTVRSALVVRN-RRRISELCS 119 67777776666555444.567888888999999988877611224466665541345566778************99999998765.5678899** PP CaKB 108 YiPkce..edkkelkeeveeikenfkkknsqtfsCyydpeekeedvllkrkydekvllhcll 167 Y + + k+e+ ++ e+++e++ ++++ C++++ +++++v+l+ + v l +l FUN_001494-T1 120 YKLRDYdcRTKEEAFQHLEKFREKWGLI-NSSYRCFHSS-RHPDKVILSNEAPSVV-LALFL 178 *654321145566667777777777776.6789**9875.679*****87665544.33332 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 870 (0.0340575); expected 510.9 (0.02) Passed bias filter: 575 (0.0225093); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2375.41 // Query: FUN_001495-T1 [L=96] Description: FUN_001495 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 12.4 16.1 0.15 12.2 16.1 1.1 1 Myc_N Myc amino-terminal region Domain annotation for each model (and alignments): >> Myc_N Myc amino-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 16.1 6e-06 0.15 216 284 .. 15 85 .. 3 94 .. 0.73 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 6e-06 Myc_N 216 ssassessssssdskalssseedtlsdsdeeeeeeeeeeEEidVV.tvekrqssskrke.stlttalsesr 284 ++++++s++ ++d + s e d ++++eeeeeee+ eEE+dV ve+ +s+ + ++++t+++e++ FUN_001495-T1 15 TEKAAGSEDGGNDAEGGYSGEGDVAEEEEEEEEEEEDYEEEVDVAeEVEEDDDASEYDTaTETETDTTETE 85 46778888999999999999999*********************845998887766555355544443333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (96 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2176 (0.085183); expected 510.9 (0.02) Passed bias filter: 716 (0.028029); expected 510.9 (0.02) Passed Vit filter: 146 (0.0057154); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 970.23 // Query: FUN_001496-T1 [L=240] Description: FUN_001496 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-12 46.8 2.4 1.4e-11 45.4 2.4 1.8 1 THAP THAP domain ------ inclusion threshold ------ 0.06 13.6 0.1 0.11 12.7 0.1 1.4 1 CitX Apo-citrate lyase phosphoribosyl-dephospho-CoA tran Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.4 2.4 1.1e-15 1.4e-11 1 63 [. 5 73 .. 5 94 .. 0.78 Alignments for each domain: == domain 1 score: 45.4 bits; conditional E-value: 1.1e-15 THAP 1 CavpgCknkskskskkkvsfhrfP.......kdkerrkkWlknikredlekkkkkksrvCskHFeee.lek 63 C++ gC+n++++ k +s+h +P + k+rrkkW++++k+++ + +++k+s++Cs HF++e +e+ FUN_001496-T1 5 CVAAGCSNQKDKA--KGISLHVIPffederpEAKRRRKKWVDFVKQKRAKWQPSKPSVICSVHFKPEdFER 73 9*******55444..349999999999999888999*********998888777559*******9886333 PP >> CitX Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 9e-06 0.11 62 103 .. 196 237 .. 175 239 .. 0.85 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 9e-06 CitX 62 kaeikilekevleektGpeallvvdadaeeiKklaielEesh 103 ++ ++ ++k++++ ++G+ v++++ +++K+++++lEe+ FUN_001496-T1 196 EEAVQAVNKQTQDPAEGCSNCTVLSNKLRKLKNRIVSLEEQA 237 34578999*******************************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (240 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1539 (0.0602466); expected 510.9 (0.02) Passed bias filter: 731 (0.0286162); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2376.19 // Query: FUN_001497-T1 [L=780] Description: FUN_001497 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-29 102.0 0.2 2.6e-11 44.5 0.0 4.4 4 Sod_Cu Copper/zinc superoxide dismutase (SODC) Domain annotation for each model (and alignments): >> Sod_Cu Copper/zinc superoxide dismutase (SODC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 8.8e-09 0.00022 1 111 [. 36 165 .. 36 175 .. 0.70 2 ! 20.1 0.0 3.7e-08 0.00096 40 107 .. 238 316 .. 190 327 .. 0.72 3 ! 44.5 0.0 1e-15 2.6e-11 1 114 [. 351 481 .. 351 498 .. 0.79 4 ! 9.9 0.0 5.1e-05 1.3 38 131 .. 565 656 .. 560 658 .. 0.69 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 8.8e-09 Sod_Cu 1 vsGtvtftqeseesgevkvegelkgltpgkhgfhiHefGdc.......tngcksagghfnptgkkhgapnde...........erhaGDLgniea. 77 ++G+v f+q ++ +g ++++++l g+++ i + + + + ++++ g+ f+p+ +k +d+ +GDL ++ FUN_001497-T1 36 IKGSVVFSQPQT-DGATTISVNLLGVNET-LKWSIRQLPMIydgnavlSCSASAIGELFDPKMAKMAPDYDSqcqndsntkfhACAVGDLSRMLGn 129 589******776.5569********9986.4577888876644322333334466******88544322233233333444444559**9977543 PP Sod_Cu 78 dadgtakvevtdsklslkg..snsiigralvvhage 111 + tak++ t+++l++ ++si+gr+lv h+g+ FUN_001497-T1 130 ITADTAKMNHTNQNLTIPTrgKHSIMGRTLVLHSGA 165 56789999999999998844699**********986 PP == domain 2 score: 20.1 bits; conditional E-value: 3.7e-08 Sod_Cu 40 dctngcksagghfnp.tgkkhgapnde..erhaGDL....gni...ea.dadgtakvevtdsklslkgsnsiigralvv 107 d t+ ck+ g+ fnp ++++++ +++ + +GDL gn+ a ++ t+k+ +tds+l l+g+ns+ig+++v FUN_001497-T1 238 DSTTYCKTLGELFNPvNNQSQNCNQEMhrNCPVGDLaskhGNVtvsVAsARQSTTKAAFTDSNLPLSGANSVIGQSIVL 316 457789*********5554444443333445578884444466332233556888889**********99*******97 PP == domain 3 score: 44.5 bits; conditional E-value: 1e-15 Sod_Cu 1 vsGtvtftqeseesgevkvegelkgltpgkhgfhiHefGdc........tngck..sagghfnptg.kkhgapnde.....erhaGDLg.niea.d 78 vsG +ftq s + ++ e++++gl++ + g+h+H +++ +++ck ag h+np++ g+p +e e ++GDL + + FUN_001497-T1 351 VSGHFKFTQRSPFD-PTLAEISVRGLQNLAGGYHVHVYPSPyykthltaSDSCKgfVAGDHWNPFDvDIKGSPANEtgtndEYEVGDLSgKYGSfQ 445 789******98855.699999999**************87766666666666668899******87433444433334555799****94443436 PP Sod_Cu 79 adgtakvevtdsklslkgsnsiigralvvhageDdl 114 + + + +v+d +l + g+nsi gr++ +h++e + FUN_001497-T1 446 NLAVFTKKVVDYNLPMFGRNSIQGRSILIHKKEKNA 481 77888888**********99************9875 PP == domain 4 score: 9.9 bits; conditional E-value: 5.1e-05 Sod_Cu 38 fGdctngcksagghfnptg.......kkhgapnde.......erhaGDLgnieadadgtakve.vtdsklslkgsnsiigralvvhageDdlgkee 118 ++d+++ c+s ++ fnp + + ++ ++GDL + +a+ + ++ + + d l l g+ns+igr + + +++ +g++ FUN_001497-T1 565 TADINKRCASLKNDFNPYEvfvegtyS------STcrptnmlRCETGDLTKKHASVKVNGGRQfYNDISLPLFGRNSVIGRGISIYEKD--MGQD- 651 5688999**********8844443322......2233444567789****998855555444415777799999999********9764..4443. PP Sod_Cu 119 kptgnaGariacG 131 r+ac+ FUN_001497-T1 652 --------RLACA 656 ........55555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (780 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 630 (0.0246624); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7425.50 // Query: FUN_001498-T1 [L=786] Description: FUN_001498 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-32 113.0 0.6 7.6e-10 39.8 0.0 4.4 4 Sod_Cu Copper/zinc superoxide dismutase (SODC) Domain annotation for each model (and alignments): >> Sod_Cu Copper/zinc superoxide dismutase (SODC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 8.9e-07 0.023 2 109 .. 43 169 .. 42 176 .. 0.62 2 ! 14.8 0.0 1.5e-06 0.039 39 112 .. 238 320 .. 196 328 .. 0.70 3 ! 39.8 0.0 3e-14 7.6e-10 2 109 .. 351 474 .. 350 482 .. 0.72 4 ! 37.8 0.0 1.3e-13 3.2e-09 25 111 .. 543 646 .. 512 657 .. 0.73 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 8.9e-07 Sod_Cu 2 sGtvtftqeseesgevkvegelkgltpg.khgfh...iHefGdc..tngcksagghfnptg.......kkhgapnde....erhaGDLgniea... 77 +G ++f++ +e +g+++v+++l+g+++ k ++ +G+ + ++++gg ++pt ++ p++e + +GDL + FUN_001498-T1 43 KGDIKFSKFHE-GGPTHVTVNLDGINETlKWAIQrlpMSYKGNAamSCHADAVGGLYDPTMalessnySTSCRPSNEsrfdKCAVGDLTGMLGnld 137 899****9877.668*********99952335441115556777334455588******8855554442222232224555556777764432111 PP Sod_Cu 78 dadgtakvevtdsklslkgsnsiigralvvha 109 ++ + +++ ++ + ++gsnsi+gr+lv + FUN_001498-T1 138 ANNSHENFTHQKLMIPITGSNSIMGRTLVLFS 169 233444444555558888899*******9865 PP == domain 2 score: 14.8 bits; conditional E-value: 1.5e-06 Sod_Cu 39 Gdctngcksagghfnptg...kkhgapnde.......erhaGDLgniea.dadgtakvevtdsklslkgsnsiigralvvhageD 112 Gd+ +ck+ g+ fnp++ k+ +++e + GD a + ++k+ ++d++l l+g ns+ig++++ ++ D FUN_001498-T1 238 GDV--SCKTPGNIFNPEStsgKNCSRERQEscpigdlTSKHGDVTVSMAtKGMSKTKAAFIDTNLPLSGMNSVIGKTIILFSKID 320 677..599********7734322222222245555554445888844443777888888**********889******9987766 PP == domain 3 score: 39.8 bits; conditional E-value: 3e-14 Sod_Cu 2 sGtvtftqeseesgevkvegelkgltpgkhgfhiHefGdc.......tngcksa..gghfnptg......kkhgapnde....erhaGDLgnie.a 77 G +ftq+s + +++ e++l gl+ ++ g+h+H+++ +++c+ a ggh+np g + g + + ++GDL + FUN_001498-T1 351 DGYFKFTQNSPFD-PTTTEISLIGLKRKAEGYHVHNYPMPwqmkftgSGSCAGAylGGHWNPYGidvkssPPAG----TgtvdQYEIGDLSGKYgS 441 6999****98855.799999999**************6444445555555665555******996543221222....144557899999854313 PP Sod_Cu 78 .dadgtakvevtdsklslkgsnsiigralvvha 109 + + + +d +l l g+nsi gr++v+h+ FUN_001498-T1 442 fYNLTHYNKVHIDYHLPLFGKNSIHGRSIVIHK 474 2334445555689999****99**********8 PP == domain 4 score: 37.8 bits; conditional E-value: 1.3e-13 Sod_Cu 25 gltpg.khgfhiHefGdc.......tngcksagghfnptg.......kkhgapnde........erhaGDLgniea.dadgtakvevtdsklslkg 96 +++ h h+H +++ + cks ggh+np + k + ++GDL +a + g +k +tds l l g FUN_001498-T1 543 STKKSvDHPWHVHVKPEGndtfaemGKRCKSLGGHYNPYNvdlsgtyK-------SscvpdnemRCEVGDLSGKNArLNVGYGKQFFTDSDLPLFG 631 4444448999***885433346555889**********9944444433.......223333345788****977775677***************9 PP Sod_Cu 97 snsiigralvvhage 111 + s++gr +v+ha++ FUN_001498-T1 632 DMSVVGRGIVIHAEN 646 899*********976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (786 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 573 (0.022431); expected 510.9 (0.02) Passed bias filter: 512 (0.0200431); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.40 # Mc/sec: 7830.69 // Query: FUN_001498-T2 [L=748] Description: FUN_001498 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-32 113.5 0.6 7.1e-10 39.9 0.0 4.4 4 Sod_Cu Copper/zinc superoxide dismutase (SODC) Domain annotation for each model (and alignments): >> Sod_Cu Copper/zinc superoxide dismutase (SODC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 8.2e-07 0.021 2 109 .. 5 131 .. 4 138 .. 0.62 2 ! 14.9 0.0 1.4e-06 0.037 39 112 .. 200 282 .. 158 290 .. 0.70 3 ! 39.9 0.0 2.8e-14 7.1e-10 2 109 .. 313 436 .. 312 444 .. 0.72 4 ! 37.9 0.0 1.2e-13 3e-09 25 111 .. 505 608 .. 474 619 .. 0.73 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 8.2e-07 Sod_Cu 2 sGtvtftqeseesgevkvegelkgltpg.khgfh...iHefGdc..tngcksagghfnptg.......kkhgapnde....erhaGDLgniea... 77 +G ++f++ +e +g+++v+++l+g+++ k ++ +G+ + ++++gg ++pt ++ p++e + +GDL + FUN_001498-T2 5 KGDIKFSKFHE-GGPTHVTVNLDGINETlKWAIQrlpMSYKGNAamSCHADAVGGLYDPTMalessnySTSCRPSNEsrfdKCAVGDLTGMLGnld 99 899****9877.668*********99952335441115556777334455588******8855554442222232224555556777764432111 PP Sod_Cu 78 dadgtakvevtdsklslkgsnsiigralvvha 109 ++ + +++ ++ + ++gsnsi+gr+lv + FUN_001498-T2 100 ANNSHENFTHQKLMIPITGSNSIMGRTLVLFS 131 233444444555558888899*******9865 PP == domain 2 score: 14.9 bits; conditional E-value: 1.4e-06 Sod_Cu 39 Gdctngcksagghfnptg...kkhgapnde.......erhaGDLgniea.dadgtakvevtdsklslkgsnsiigralvvhageD 112 Gd+ +ck+ g+ fnp++ k+ +++e + GD a + ++k+ ++d++l l+g ns+ig++++ ++ D FUN_001498-T2 200 GDV--SCKTPGNIFNPEStsgKNCSRERQEscpigdlTSKHGDVTVSMAtKGMSKTKAAFIDTNLPLSGMNSVIGKTIILFSKID 282 677..599********7734322222222245555554445888844443777888888**********889******9987766 PP == domain 3 score: 39.9 bits; conditional E-value: 2.8e-14 Sod_Cu 2 sGtvtftqeseesgevkvegelkgltpgkhgfhiHefGdc.......tngcksa..gghfnptg......kkhgapnde....erhaGDLgnie.a 77 G +ftq+s + +++ e++l gl+ ++ g+h+H+++ +++c+ a ggh+np g + g + + ++GDL + FUN_001498-T2 313 DGYFKFTQNSPFD-PTTTEISLIGLKRKAEGYHVHNYPMPwqmkftgSGSCAGAylGGHWNPYGidvkssPPAG----TgtvdQYEIGDLSGKYgS 403 6999****98855.799999999**************6444445555555665555******996543221222....144557899999854313 PP Sod_Cu 78 .dadgtakvevtdsklslkgsnsiigralvvha 109 + + + +d +l l g+nsi gr++v+h+ FUN_001498-T2 404 fYNLTHYNKVHIDYHLPLFGKNSIHGRSIVIHK 436 2334445555689999****99**********8 PP == domain 4 score: 37.9 bits; conditional E-value: 1.2e-13 Sod_Cu 25 gltpg.khgfhiHefGdc.......tngcksagghfnptg.......kkhgapnde........erhaGDLgniea.dadgtakvevtdsklslkg 96 +++ h h+H +++ + cks ggh+np + k + ++GDL +a + g +k +tds l l g FUN_001498-T2 505 STKKSvDHPWHVHVKPEGndtfaemGKRCKSLGGHYNPYNvdlsgtyK-------SscvpdnemRCEVGDLSGKNArLNVGYGKQFFTDSDLPLFG 593 4444448999***885433346555889**********9944444433.......223333345788****977775677***************9 PP Sod_Cu 97 snsiigralvvhage 111 + s++gr +v+ha++ FUN_001498-T2 594 DMSVVGRGIVIHAEN 608 899*********976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (748 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 480 (0.0187904); expected 510.9 (0.02) Passed bias filter: 433 (0.0169505); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 7495.48 // Query: FUN_001499-T1 [L=101] Description: FUN_001499 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1134 (0.0443922); expected 510.9 (0.02) Passed bias filter: 661 (0.0258759); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1025.15 // Query: FUN_001500-T1 [L=790] Description: FUN_001500 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-29 101.5 1.8 8.6e-10 39.6 0.1 4.3 4 Sod_Cu Copper/zinc superoxide dismutase (SODC) Domain annotation for each model (and alignments): >> Sod_Cu Copper/zinc superoxide dismutase (SODC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 2e-09 5e-05 2 111 .. 37 165 .. 36 174 .. 0.69 2 ! 22.4 0.0 7.2e-09 0.00018 3 112 .. 192 321 .. 190 332 .. 0.65 3 ! 39.6 0.1 3.4e-14 8.6e-10 1 110 [. 351 476 .. 351 484 .. 0.76 4 ! 11.4 0.0 1.8e-05 0.45 33 111 .. 557 650 .. 516 661 .. 0.75 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 2e-09 Sod_Cu 2 sGtvtftqeseesgevkvegelkgltpgkhgfhiHefGdc.....tngck..sagghfnptgkkhgapn.de...........erhaGDLgniea. 77 +G+v f+q ++ +g ++++++l+g+++ i + + + + +c+ + g+ f+p+ +k pn d+ +GDL ++ FUN_001500-T1 37 EGSVVFSQPQT-DGATTISVNLSGVNET-LKWSIRQLPMIydgnaALSCSasAIGELFDPKMAKIA-PNyDSrcqndnntkfhACAVGDLSRMLGn 129 79******777.5569*********986.4577888866644332223334255******885443.22133333333443444559**9977543 PP Sod_Cu 78 dadgtakvevtdsklslkg..snsiigralvvhage 111 + tak++ t+++l++ ++si+gr+lv h+g+ FUN_001500-T1 130 ITADTAKMNHTNQNLTIPTrgEHSIMGRTLVLHSGA 165 56789999999999998844699**********987 PP == domain 2 score: 22.4 bits; conditional E-value: 7.2e-09 Sod_Cu 3 Gtvtftqeseesge...vkvegelkgltpgkhgfhiHef......Gdctngcksagghfnptgkkhgapndeerh....aGDL....gni...ea. 77 G v+f+q + ++++ v + + + ++g i++ d t+ ck+ g+ fnp ++ h ++ ++e h +GDL gn+ a FUN_001500-T1 192 GFVYFRQVEGKQDTtifVDLFFVNNANSQGDFNWQINQGlldtdaSDFTTYCKTLGELFNPVNS-HSQNCNQEMHrncpVGDLaskhGNVtvsLAs 286 788888877655433333333333444557778888876655444566999**********663.3333333233334478884444466322243 PP Sod_Cu 78 dadgtakvevtdsklslkgsnsiigralvvhageD 112 ++ t+k+ +tds+l l+g+ns++g+++v +D FUN_001500-T1 287 ARQSTTKAAFTDSNLPLSGANSVVGKSIVLFPVND 321 566888999**********99********866555 PP == domain 3 score: 39.6 bits; conditional E-value: 3.4e-14 Sod_Cu 1 vsGtvtftqeseesgevkvegelkgltpgkhgfhiHefGdc....tngck........sagghfnptg......kkhgapndeerhaGDLg.niea 77 vsG +ftq+s + ++ e++l+gl+ ++hg+h+H++++ + ag h+np++ g + ++ ++GDL + FUN_001500-T1 351 VSGYFEFTQASPFD-PTIAEIHLNGLQSKAHGYHVHAYPSPdhkkL---SgrdachgfIAGDHWNPFDidintsPAEGTGTYDKYEIGDLSgKYGS 442 7899*****98855.799999999**************86643440...14455558899******996664432233223337899***944433 PP Sod_Cu 78 .dadgtakvevtdsklslkgsnsiigralvvhag 110 + t + + +d +l l g+nsi gr++ h++ FUN_001500-T1 443 fLNRSTYDKRHIDYNLPLFGPNSIQGRSVLFHNH 476 36778888889*********99*******99986 PP == domain 4 score: 11.4 bits; conditional E-value: 1.8e-05 Sod_Cu 33 fhiHefGdc......tngcksagghfnptg.......kkhgapnde.......erhaGDLgniea.dadgtakvevtdsklslkgsnsiigralvv 107 +h +Gd ++ c+s + +np+g + + ++GDL + +a + ++ + d +l l g+ns++gr + v FUN_001500-T1 557 IHLDPVGDDavapelNKRCMSLHENLNPFGvygegtyYT------AcsptnmlRCEMGDLTKKHApFKVNGGRQFYHDVNLPLFGKNSVVGRGMTV 646 5555666555566658899999******99444332212......233334567789****9998555556666679999*****99********* PP Sod_Cu 108 hage 111 h+++ FUN_001500-T1 647 HEKN 650 *985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (790 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 561 (0.0219612); expected 510.9 (0.02) Passed bias filter: 510 (0.0199648); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7536.46 // Query: FUN_001501-T1 [L=288] Description: FUN_001501 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (288 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 500 (0.0195733); expected 510.9 (0.02) Passed bias filter: 483 (0.0189078); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2910.76 // Query: FUN_001502-T1 [L=91] Description: FUN_001502 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (91 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 362 (0.0141711); expected 510.9 (0.02) Passed bias filter: 293 (0.01147); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 930.07 // Query: FUN_001503-T1 [L=288] Description: FUN_001503 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (288 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 587 (0.0229791); expected 510.9 (0.02) Passed bias filter: 552 (0.0216089); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.35s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2832.52 // Query: FUN_001504-T1 [L=1180] Description: FUN_001504 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-143 476.8 0.6 9.4e-143 476.3 0.6 1.2 1 RNA_pol_Rpb2_6 RNA polymerase Rpb2, domain 6 2.8e-71 239.8 0.0 4e-71 239.3 0.0 1.2 1 RNA_pol_Rpb2_1 RNA polymerase beta subunit 4.4e-53 180.3 0.0 8.8e-53 179.3 0.0 1.5 1 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2 1.8e-32 112.1 0.5 4.2e-32 110.9 0.2 1.8 2 RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7 6.3e-26 90.7 0.6 1.5e-25 89.5 0.6 1.7 1 RNA_pol_Rpb2_4 RNA polymerase Rpb2, domain 4 6.3e-25 87.6 0.0 2e-24 86.0 0.0 1.9 1 RNA_pol_Rpb2_3 RNA polymerase Rpb2, domain 3 5.9e-19 69.2 0.7 1.8e-18 67.6 0.7 1.9 1 RNA_pol_Rpb2_5 RNA polymerase Rpb2, domain 5 ------ inclusion threshold ------ 0.15 12.5 1.6 0.41 11.2 1.6 1.8 1 DUF5817 Domain of unknown function (DUF5817) Domain annotation for each model (and alignments): >> RNA_pol_Rpb2_6 RNA polymerase Rpb2, domain 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 476.3 0.6 2.9e-146 9.4e-143 1 373 [] 709 1082 .. 709 1082 .. 0.95 Alignments for each domain: == domain 1 score: 476.3 bits; conditional E-value: 2.9e-146 RNA_pol_Rpb2_6 1 vaslipfvehnqsprivyqsamekqalgiyalnklkrsdqktyvllypqkPlvktkkvelgdlgelplGqnaiVAvmsytGYniEDaiilnks 93 +as+ipf++hnqspr++yqsam+kqa+g+y +n++ r+d+ +vl+ypqkPlv+t+++e+++++elp+G nai A++sytGYn+ED++i+n s FUN_001504-T1 709 CASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNYHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINAIAAIASYTGYNQEDSVIMNAS 801 799****************************************************************************************** PP RNA_pol_Rpb2_6 94 svdrgvftsivikeiearktklge.keeitrdipnv.....seealkkLdedGivkvgaevkkgdilvgkvseteltkllraifgekake.vk 179 ++drg+++s+++++++ ++ k+g +ee++++++++ +++ ++kLd+dG++++g++v+ +d++vgk+ +l ++ ++ +g++++ +k FUN_001504-T1 802 AIDRGLYRSVFYRSYRDQESKRGMdQEETFEKPTRDscqgmRNAVYDKLDDDGLISPGTRVSGDDVIVGKTV--TLPENDDELEGTTRRFtKK 892 **************99977776651577777777779999999***************************73..2334455566666665589 PP RNA_pol_Rpb2_6 180 dtslkvksgeegvvdkvkvlkdeeskeviklvkvrirqkRkpevGDKfasrhGqKGvvslilpqeDmPftedGivpDiilNPhgvPsRmtigq 272 d+s+ ++++e+g+vd+v+v + ++e++k+ k+++r+ R p++GDKfasrhGqKG+++++++qeDmPft +Gi+pD+i+NPh++PsRmtig+ FUN_001504-T1 893 DSSTFLRPSETGIVDQVMV---TINQEGYKFTKIKVRSVRVPQIGDKFASRHGQKGTCGITYRQEDMPFTCEGITPDVIINPHAIPSRMTIGH 982 *******************...99********************************************************************* PP RNA_pol_Rpb2_6 273 llelllgkaaalkgkkvdatvFegaekeveeiaeeLekagfeasGkevlydGrtGekleaeifvGviYyqkLkhlvdDKihaRstGpvslltr 365 l+e+l gk++a kg+ dat+F+ a +v+++++ L+ g++ G+evly+G+tG+kl+a++f+G++Yyq+Lkh+vdDKih+R++Gpv++ltr FUN_001504-T1 983 LIECLQGKVSANKGEIGDATPFNDA-VNVQKVSQLLNDYGYHLRGNEVLYNGFTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILTR 1074 ***********************87.999**************************************************************** PP RNA_pol_Rpb2_6 366 QPleGrar 373 QP+eGr+r FUN_001504-T1 1075 QPMEGRSR 1082 ******97 PP >> RNA_pol_Rpb2_1 RNA polymerase beta subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 239.3 0.0 1.2e-74 4e-71 1 202 [. 39 442 .. 39 443 .. 0.98 Alignments for each domain: == domain 1 score: 239.3 bits; conditional E-value: 1.2e-74 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF RNA_pol_Rpb2_1 1 gLvkqqldSFnefvendlqkiikeeakieseeeeqssgee......lslkfeqirlgkPvvsesdgstreiyPqearlrnltYsaplyvdleksv 89 gLv+qqldSF+ef+++++q+i++++++i ++ e+ +++++ + lkfeqi+l+kP+++e+dg+ ++P+earlrnltYsaplyvd++k++ FUN_001504-T1 39 GLVRQQLDSFDEFIQMSVQRIVEDSPEIDLQAESLHMTSDtetpprYLLKFEQIYLSKPTHWEKDGAPSPMMPNEARLRNLTYSAPLYVDITKTM 133 69********************************99988889***************************************************99 PP xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................ RF RNA_pol_Rpb2_1 90 kekd.nkeekkeeevdiGelPiMlrskacilseaseeelvelgEcpldpGGyFiinGsekvivaqek............................ 155 +++d + ++++++iG++PiMlrs++c l++ ++++l+el+EcpldpGGyFiinGsekv++aqek FUN_001504-T1 134 IKEDdDSAVTQHSKMFIGKIPIMLRSTYCLLNGQTDRDLTELNECPLDPGGYFIINGSEKVLIAQEKmatntvyvfskkdskysftaeirscleh 228 877757788899*********************************************************************************** PP ............................................................................................... RF RNA_pol_Rpb2_1 156 ............................................................................................... 155 FUN_001504-T1 229 ssrptstmwvsmlakgsqggrksaigqrivgtlpyirqeipimivfralgfvadrdilehiiydfddpemmemvkpsldeafviqeqnvalnfig 323 *********************************************************************************************** PP ........................................................................xxxxxxxxxxxxxxxxxxxxxxx RF RNA_pol_Rpb2_1 156 ........................................................................laGeLlaslfrellkklakdvre 178 laG+Lla lfr l+++l k+vr+ FUN_001504-T1 324 srgarpgvtkekrikyareilqkemlphvgvsdfcetkkayflgymvhrlllaalgrrelddrdhygnkrldLAGPLLAFLFRGLFRNLMKEVRM 418 *********************************************************************************************** PP xxxxxxxxxxxxxxxxxxxxxxxx RF RNA_pol_Rpb2_1 179 rlqkslkkpddlmlqllvkaktit 202 + qk +++++d++ +l++k k it FUN_001504-T1 419 YAQKFIDRGKDFNIELALKPKVIT 442 ******************999998 PP >> RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 179.3 0.0 2.8e-56 8.8e-53 1 190 [] 202 395 .. 202 395 .. 0.96 Alignments for each domain: == domain 1 score: 179.3 bits; conditional E-value: 2.8e-56 RNA_pol_Rpb2_2 1 rsngiyvekekdknki................satvtsslisnrgsvlklekdgktliwsriskkrkipivillkAlglvsdreIlericydsed 79 ++n++yv+++kd + s++++s+l++++ + k ++++++ ++++++++ipi+i+++Alg+v dr+Ile+i+yd++d FUN_001504-T1 202 ATNTVYVFSKKDSKYSftaeirsclehssrptSTMWVSMLAKGSQGGRKSAIGQRIV-GTLPYIRQEIPIMIVFRALGFVADRDILEHIIYDFDD 295 589**********9999***********************************99988.6779********************************* PP RNA_pol_Rpb2_2 80 pqlleelleeleekeeiytqeealdyigk.vvalrrgeearlqsarellqkrydlgkigreklnkhlglseslenerlkaqdilamidrLlelkl 173 p+++e+++++l e+++i++q+ al++ig+ + + + ++e+r+++are+l ++e+l+ h+g+s+ +e++ ka+++++m++rLl+++l FUN_001504-T1 296 PEMMEMVKPSLDEAFVIQEQNVALNFIGSrGARPGVTKEKRIKYAREIL---------QKEMLP-HVGVSDFCETK--KAYFLGYMVHRLLLAAL 378 *****************************88888888888888888888.........69****.***********..***************** PP RNA_pol_Rpb2_2 174 grrevDDiDhlgnkRvr 190 grre+DD+Dh+gnkR++ FUN_001504-T1 379 GRRELDDRDHYGNKRLD 395 ***************96 PP >> RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.0 0.0 8 2.6e+04 60 75 .. 333 348 .. 330 349 .. 0.82 2 ! 110.9 0.2 1.3e-35 4.2e-32 1 85 [. 1084 1174 .. 1084 1176 .. 0.98 Alignments for each domain: == domain 1 score: -4.0 bits; conditional E-value: 8 RNA_pol_Rpb2_7 60 ekveipesfklLlkeL 75 ++ +i ++ ++L ke+ FUN_001504-T1 333 KEKRIKYAREILQKEM 348 5567999*******98 PP == domain 2 score: 110.9 bits; conditional E-value: 1.3e-35 RNA_pol_Rpb2_7 1 GGlRfGEMEvwaleayGaaklLkerltikSDavevdvcgrckllaaan......eCkivkgeekiekveipesfklLlkeLqslaikvkll 85 GGlRfGEME+++++a+Gaa++L+erl++ SD ++ +vc+ c+l+a+an eC+ +k++++++++++p+++klL++eL+s+ i+++++ FUN_001504-T1 1084 GGLRFGEMERDCMIAHGAAQFLNERLFEVSDPYSCHVCNLCGLIAIANlrnntfECRGCKNKTQVSRIRMPYAAKLLFQELMSMSIAPRMM 1174 9*********************************************99****************************************997 PP >> RNA_pol_Rpb2_4 RNA polymerase Rpb2, domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 89.5 0.6 4.6e-29 1.5e-25 1 62 [] 568 630 .. 568 630 .. 0.98 Alignments for each domain: == domain 1 score: 89.5 bits; conditional E-value: 4.6e-29 RNA_pol_Rpb2_4 1 VflNGnlvGvtrdpeelvetlrklRrkgk.iseevsividerekevrIatDaGRvcRPLiive 62 +f+NG +vG++rdp++l++tlrklRr+ + i +evs+v+d reke+rI+tDaGR+cRPL+ive FUN_001504-T1 568 IFVNGCWVGIHRDPDQLMSTLRKLRRQMDiIVSEVSMVRDFREKEIRIYTDAGRICRPLLIVE 630 8****************************999******************************8 PP >> RNA_pol_Rpb2_3 RNA polymerase Rpb2, domain 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 86.0 0.0 6.2e-28 2e-24 1 68 [] 469 533 .. 469 533 .. 0.98 Alignments for each domain: == domain 1 score: 86.0 bits; conditional E-value: 6.2e-28 RNA_pol_Rpb2_3 1 qvldrlNylstlshlrrvsslrGglsreskttevRklhpshwGriCpveTPeGencGlvkhLallakv 68 qvl+rl++ stlshlrr++s+ + re k +++R+lh++hwG+iCp+eTPeG+++Glvk+Lal+a + FUN_001504-T1 469 QVLNRLTFASTLSHLRRLNSP---IGREGKLARPRQLHNTHWGMICPAETPEGHAVGLVKNLALMAYI 533 89*******************...*****************************************987 PP >> RNA_pol_Rpb2_5 RNA polymerase Rpb2, domain 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.6 0.7 5.7e-22 1.8e-18 1 66 [] 654 702 .. 654 702 .. 0.95 Alignments for each domain: == domain 1 score: 67.6 bits; conditional E-value: 5.7e-22 RNA_pol_Rpb2_5 1 WsdLlkegvvEylDaeEEetamIamtpedleesreekegeeeedeerlkakanskahtyTHcEIhP 66 W++L++ g+vEy+D++EEet+m+amtp+dl ++ ++ +++tyTHcEIhP FUN_001504-T1 654 WQELVAGGIVEYIDVNEEETVMVAMTPDDLMVEKGQA-----------------YCSTYTHCEIHP 702 ******************************9998777.................699********9 PP >> DUF5817 Domain of unknown function (DUF5817) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 1.6 0.00013 0.41 1 37 [. 1116 1152 .. 1116 1158 .. 0.89 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00013 DUF5817 1 YaVVGCsdCsalwvvedrpetaqCprCgkrhqtekLk 37 Y+ +C+ C+ + + + r++t +C C+++ q+++++ FUN_001504-T1 1116 YSCHVCNLCGLIAIANLRNNTFECRGCKNKTQVSRIR 1152 55668999999999999*****************998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1180 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 697 (0.0272852); expected 510.9 (0.02) Passed bias filter: 641 (0.025093); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.44u 0.41s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 11276.30 // Query: FUN_001505-T1 [L=410] Description: FUN_001505 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (410 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 713 (0.0279115); expected 510.9 (0.02) Passed bias filter: 471 (0.0184381); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4019.29 // Query: FUN_001506-T1 [L=360] Description: FUN_001506 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-22 78.6 7.7 6.2e-22 78.1 6.6 1.9 1 NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 0.0088 16.4 4.5 0.0088 16.4 4.5 3.1 4 GeBP-like_C Glabrous-enhancer-binding protein-like family, C ------ inclusion threshold ------ 3.2 8.3 12.4 0.25 11.8 1.9 3.1 3 PUMA_CC PUMA coiled-coil Domain annotation for each model (and alignments): >> NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.1 6.6 7.3e-26 6.2e-22 1 75 [. 1 75 [. 1 87 [. 0.95 Alignments for each domain: == domain 1 score: 78.1 bits; conditional E-value: 7.3e-26 NRBF2_MIT 1 meaplnlahqqsrradrllaaGkyeeaischkkaaaylseamkltkseqahlslelqreshikqllliqerwkra 75 m++p+n ahqq+r+a+ l++ k+ eai ch+ka ++l eamk+t+ ++a +sl+lq + h +q ++++e+wk FUN_001506-T1 1 MDSPINWAHQQERQAEALVSHRKFAEAIVCHRKALEFLQEAMKMTEVKEALISLQLQCNNHCRQERILKEKWKLW 75 89**********************************************************************965 PP >> GeBP-like_C Glabrous-enhancer-binding protein-like family, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.1 0.55 4.7e+03 37 49 .. 38 50 .. 22 55 .. 0.71 2 ! 16.4 4.5 1e-06 0.0088 18 62 .. 64 108 .. 62 110 .. 0.91 3 ? -2.7 0.0 0.96 8.2e+03 33 45 .. 157 169 .. 125 175 .. 0.48 4 ? 2.5 0.2 0.022 1.9e+02 33 57 .. 304 328 .. 290 331 .. 0.88 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.55 GeBP-like_C 37 iEekwkalqakel 49 ++e +k+ ++ke FUN_001506-T1 38 LQEAMKMTEVKEA 50 4578888888875 PP == domain 2 score: 16.4 bits; conditional E-value: 1e-06 GeBP-like_C 18 dEdsvkqkWslvpvetKkkiEekwkalqakelelvlqKtdllkev 62 +E+++k+kW+l +e+ k+i e+ k+lq + + +++K + l +v FUN_001506-T1 64 QERILKEKWKLWEIEQEKQIHEQQKMLQLRQNQEITEKQNSLLNV 108 5999**************************999999998887766 PP == domain 3 score: -2.7 bits; conditional E-value: 0.96 GeBP-like_C 33 tKkkiEekwkalq 45 t +++E +++ lq FUN_001506-T1 157 TAQELEGQVRDLQ 169 2355666666665 PP == domain 4 score: 2.5 bits; conditional E-value: 0.022 GeBP-like_C 33 tKkkiEekwkalqakelelvlqKtd 57 +K + E+ + +l ke ++ + K++ FUN_001506-T1 304 EKERTEDLMELLGLKETDVQMAKAN 328 79999***************99986 PP >> PUMA_CC PUMA coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.5 0.029 2.5e+02 38 72 .. 44 78 .. 41 82 .. 0.82 2 ? -0.9 0.5 0.27 2.3e+03 35 50 .. 80 95 .. 78 106 .. 0.71 3 ? 11.8 1.9 3e-05 0.25 4 40 .. 159 195 .. 153 197 .. 0.88 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.029 PUMA_CC 38 LadakreianqqkalDdaeRevrrLedrlrasese 72 +++ k+ + + q + + +R+ r L+++ + e e FUN_001506-T1 44 MTEVKEALISLQLQCNNHCRQERILKEKWKLWEIE 78 7899999********************87654443 PP == domain 2 score: -0.9 bits; conditional E-value: 0.27 PUMA_CC 35 eKqLadakreianqqk 50 eKq+ + ++ ++ +q+ FUN_001506-T1 80 EKQIHEQQKMLQLRQN 95 6777777777766655 PP == domain 3 score: 11.8 bits; conditional E-value: 3e-05 PUMA_CC 4 qqlqrKLknaekqiselktklesaeearRrLeKqLad 40 q+l+ +++ + q+ l + le+ + ++RrL+K L+d FUN_001506-T1 159 QELEGQVRDLQMQVLTLSQNLEDCNRENRRLQKALND 195 7889999999999999999999999999999999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (360 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1927 (0.0754355); expected 510.9 (0.02) Passed bias filter: 574 (0.0224702); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 3516.52 // Query: FUN_001507-T1 [L=1560] Description: FUN_001507 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-143 466.4 254.4 3.8e-13 49.9 7.1 15.6 15 TSP_1 Thrombospondin type 1 domain 4.8e-96 315.4 270.7 1.5e-08 35.2 10.0 16.0 16 TSP1_spondin Spondin-like TSP1 domain 2.1e-52 178.6 0.0 2.1e-52 178.6 0.0 2.0 1 Trypsin Trypsin 4.8e-39 132.4 44.1 7.8e-14 51.7 6.8 4.4 4 LRR_8 Leucine rich repeat 1.8e-37 127.9 255.9 0.0027 18.4 12.3 15.8 15 TSP1_ADAMTS Thrombospondin type 1 domain 1.3e-34 119.0 177.2 0.0001 23.2 3.7 16.6 16 TSP1_CFP_C CFP-like, C-terminal thrombospondin type 1 doma 4.8e-22 78.4 259.4 0.0034 18.1 13.5 17.6 15 TSP1_CCN CCN3 Nov like TSP1 domain 8e-19 67.7 33.5 5.1e-08 33.4 2.5 5.4 6 LRR_4 Leucine Rich repeats (2 copies) 1.5e-16 60.9 0.5 1.6e-08 35.0 0.2 2.5 2 LRR_5 BspA type Leucine rich repeat region (6 copies) 3e-07 29.7 28.2 1.2 10.1 0.7 9.3 8 LRR_1 Leucine Rich Repeat 0.00014 22.7 0.1 0.00045 21.1 0.1 1.9 1 DUF1986 Domain of unknown function (DUF1986) 0.0069 16.4 0.3 0.0069 16.4 0.3 3.2 3 LRR_9 Leucine-rich repeat ------ inclusion threshold ------ 0.014 15.6 6.1 0.76 9.9 0.5 2.4 2 LRR_LRWD1 Leucine-rich repeat and WD repeat-containing pr 0.058 14.4 0.1 0.058 14.4 0.1 4.1 2 LRRCT Leucine rich repeat C-terminal domain 6.2 6.9 9.6 17 5.5 1.7 2.7 3 LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain Domain annotation for each model (and alignments): >> TSP_1 Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.6 13.7 2.7e-11 4.5e-08 2 49 .] 375 424 .. 374 424 .. 0.97 2 ! 36.8 10.7 2.7e-12 4.6e-09 2 49 .] 430 479 .. 429 479 .. 0.96 3 ! 43.6 9.6 2.1e-14 3.5e-11 2 49 .] 487 538 .. 486 538 .. 0.90 4 ! 49.9 7.1 2.2e-16 3.8e-13 2 49 .] 546 595 .. 545 595 .. 0.98 5 ! 31.1 12.3 1.6e-10 2.8e-07 1 49 [] 602 649 .. 602 649 .. 0.98 6 ! 39.2 7.2 5e-13 8.5e-10 2 49 .] 657 706 .. 656 706 .. 0.95 7 ! 42.9 9.8 3.4e-14 5.7e-11 2 49 .] 714 763 .. 713 763 .. 0.97 8 ! 42.6 8.9 4.1e-14 7e-11 2 49 .] 771 820 .. 770 820 .. 0.96 9 ! 41.4 13.1 1e-13 1.7e-10 1 49 [] 827 877 .. 827 877 .. 0.98 10 ! 45.0 11.8 7.4e-15 1.3e-11 1 49 [] 884 934 .. 884 934 .. 0.98 11 ! 30.4 5.5 2.7e-10 4.6e-07 2 28 .. 942 970 .. 941 995 .. 0.80 12 ! 31.4 7.9 1.4e-10 2.3e-07 2 49 .] 1004 1049 .. 1003 1049 .. 0.95 13 ! 36.0 6.1 4.8e-12 8.2e-09 1 49 [] 1056 1106 .. 1056 1106 .. 0.94 14 ! 21.5 7.9 1.6e-07 0.00028 1 49 [] 1118 1172 .. 1118 1172 .. 0.88 15 ! 31.0 10.8 1.8e-10 3.1e-07 3 49 .] 1178 1223 .. 1176 1223 .. 0.97 Alignments for each domain: == domain 1 score: 33.6 bits; conditional E-value: 2.7e-11 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 +ws Ws+Csv+Cg+G ++ +R c + ++g+ C g +++t++C+ +C FUN_001507-T1 375 EWSSWSACSVSCGNGRQESTRNCTKLtpDEDGTECIGRSVRTRKCQGTEC 424 8************************99999*****************999 PP == domain 2 score: 36.8 bits; conditional E-value: 2.7e-12 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 wseW++Cs TC+ G+ vR+R+ck + + +C+g +qet++C+ ++C FUN_001507-T1 430 AWSEWTDCSRTCSFGVAVRTRLCKRMavGVSNDSCEGVSQETRVCSRQQC 479 5*************************9888899************99999 PP == domain 3 score: 43.6 bits; conditional E-value: 2.1e-14 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqe..teaCkmkkC 49 ws WspCsvTC+ G rvR+R c++p q+gg++C+ +++ t++C C FUN_001507-T1 487 SWSLWSPCSVTCSWGNRVRTRNCNNPrpQHGGKSCPVTDRSvaTQICYLGSC 538 6**********************************988765559***77666 PP == domain 4 score: 49.9 bits; conditional E-value: 2.2e-16 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 ws WspC+ +Cg G+r+R+R c++p q gg +C+g++++ + C+ k+C FUN_001507-T1 546 FWSYWSPCNSSCGTGTRTRHRICNNPtpQYGGDFCNGTVIQQKNCSLKEC 595 6************************************************* PP == domain 5 score: 31.1 bits; conditional E-value: 1.6e-10 TSP_1 1 spwseWspCsvTCgkGirvRqRtckspqkggepCtgeaqeteaCkmkkC 49 s ws Ws Cs TC+ G +vR+R c++ g++C g+ ++++ C+ +C FUN_001507-T1 602 SSWSRWSVCSRTCSVGWQVRSRNCSNH-YVGQSCRGNFSDVRNCNVGPC 649 78***********************99.9****************9999 PP == domain 6 score: 39.2 bits; conditional E-value: 5e-13 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 w+ Ws+Cs+TC G+r R Rtc++p ++gg C+g+ e+ C+ C FUN_001507-T1 657 AWTSWSDCSKTCNTGSRFRNRTCSNPppEHGGRTCPGNYYENIHCDLGSC 706 6**************************99**********99999988777 PP == domain 7 score: 42.9 bits; conditional E-value: 3.4e-14 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 ws Ws Cs+TC +G+r R+R+c++p q+gg +C+g+++e C+ +C FUN_001507-T1 714 AWSAWSGCSTTCASGTRSRRRSCSNPspQHGGLNCPGNSSEEAYCNFGPC 763 7*********************************************9999 PP == domain 8 score: 42.6 bits; conditional E-value: 4.1e-14 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 ws Ws+Cs++CgkG++ R+Rtc+++ ++gg +C+ge +++ C C FUN_001507-T1 771 TWSLWSECSKSCGKGTKNRSRTCNNTfpRFGGRNCSGEGKQIMSCALVLC 820 6********************************************98888 PP == domain 9 score: 41.4 bits; conditional E-value: 1e-13 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 s+ws+Ws+Cs +C+ G++ R+Rtc++p ++gg+ Ctg+a+e e C+ k+C FUN_001507-T1 827 SEWSKWSECSESCSTGVKFRTRTCSNPspRNGGQGCTGDAKELEGCQPKPC 877 89**************************999****************9999 PP == domain 10 score: 45.0 bits; conditional E-value: 7.4e-15 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 s+ws W++Cs+TCg+G++ R+R c + ++g + Ctg++ + + C ++ C FUN_001507-T1 884 SEWSNWTDCSTTCGNGTKSRHRNCENLspRHGEKTCTGDVYQRKHCFQQAC 934 89***********************99999****************99999 PP == domain 11 score: 30.4 bits; conditional E-value: 2.7e-10 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..q 28 +ws W++Cs+TC G+++R+R c++ + FUN_001507-T1 942 EWSHWTDCSTTCDVGQQTRIRFCNGSncK 970 8***********************87332 PP == domain 12 score: 31.4 bits; conditional E-value: 1.4e-10 TSP_1 2 pwseWspCsvTCgkGirvRqRtckspqkggepCtgeaqeteaCkmkkC 49 +w++Ws+Cs Cg G++ R R c++ +g +C+g ++++C k C FUN_001507-T1 1004 EWTPWSQCSSRCGFGKQHRLRNCSAV--EGDSCAGSLMQVKVCYRKYC 1049 8***********************99..9**************88777 PP == domain 13 score: 36.0 bits; conditional E-value: 4.8e-12 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCkmkkC 49 s ws W++Cs TCg G+++ R c +p q gg C g+++ +++C C FUN_001507-T1 1056 SSWSAWTECSLTCGIGVQEKLRFCTNPkpQGGGDLCHGKDVTVRPCIVTRC 1106 78*************************98889999***********77776 PP == domain 14 score: 21.5 bits; conditional E-value: 1.6e-07 TSP_1 1 spwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqe....teaCkmkkC 49 s w Ws+Cs C+ r+R+R+c + ++ ++C+ ++ + +C+m+ C FUN_001507-T1 1118 SSWARWSQCSANCSRRYRTRTRYCRRRlnPFLLGNCSKDTGPiqvqSGVCEMQAC 1172 78************************************98663333668999999 PP == domain 15 score: 31.0 bits; conditional E-value: 1.8e-10 TSP_1 3 wseWspCsvTCgkGirvRqRtckspqkggepCtgeaqeteaCkmkkC 49 w W Cs++Cg+G r R R+c s+ + ++C+g+ +te C+ C FUN_001507-T1 1178 WYSWGVCSKSCGSGLRKRVRACRSN-TNEKNCQGDYLQTERCNTNSC 1223 999**********************.9***************99999 PP >> TSP1_spondin Spondin-like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 14.5 1.1e-09 1.8e-06 4 52 .] 374 424 .. 372 424 .. 0.94 2 ! 21.3 10.6 1.9e-07 0.00033 5 52 .] 430 479 .. 427 479 .. 0.90 3 ! 27.9 10.2 1.7e-09 2.9e-06 4 52 .] 486 538 .. 484 538 .. 0.86 4 ! 29.9 8.8 4.2e-10 7.2e-07 4 52 .] 545 595 .. 543 595 .. 0.92 5 ! 21.4 14.5 1.9e-07 0.00032 3 52 .] 601 649 .. 600 649 .. 0.95 6 ! 34.8 9.2 1.2e-11 2.1e-08 5 52 .] 657 706 .. 654 706 .. 0.91 7 ! 35.2 10.0 8.9e-12 1.5e-08 4 52 .] 713 763 .. 711 763 .. 0.92 8 ! 28.7 9.7 9.6e-10 1.6e-06 4 52 .] 770 820 .. 768 820 .. 0.90 9 ! 33.4 13.6 3.3e-11 5.6e-08 3 52 .] 826 877 .. 825 877 .. 0.93 10 ! 33.9 13.8 2.3e-11 3.9e-08 4 52 .] 884 934 .. 882 934 .. 0.95 11 ! 19.7 6.0 6.5e-07 0.0011 4 25 .. 941 962 .. 939 996 .. 0.87 12 ! 25.0 8.0 1.4e-08 2.4e-05 4 52 .] 1003 1049 .. 1001 1049 .. 0.95 13 ! 29.4 5.9 5.9e-10 1e-06 4 52 .] 1056 1106 .. 1054 1106 .. 0.92 14 ! 15.0 7.9 1.9e-05 0.032 4 29 .. 1118 1143 .. 1116 1172 .. 0.76 15 ! 22.4 13.4 9.1e-08 0.00016 4 52 .] 1176 1223 .. 1173 1223 .. 0.95 16 ? -3.3 0.0 9.7 1.6e+04 5 25 .. 1289 1310 .. 1288 1311 .. 0.75 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 1.1e-09 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRev.ivepqnggkpCpell.errkCneepC 52 +eWs+Ws Cs++Cg+G+q+ tR+ + p+++g +C ++ +rkC++++C FUN_001507-T1 374 TEWSSWSACSVSCGNGRQESTRNCtKLTPDEDGTECIGRSvRTRKCQGTEC 424 79*********************95579***********99*********9 PP == domain 2 score: 21.3 bits; conditional E-value: 1.9e-07 TSP1_spondin 5 eWseWseCsktCgkGvqtRtRevivepqn.ggkpCpell.errkCneepC 52 +WseW++Cs+tC+ Gv RtR ++ + ++C + e+r C++++C FUN_001507-T1 430 AWSEWTDCSRTCSFGVAVRTRLCKRMAVGvSNDSCEGVSqETRVCSRQQC 479 7**********************88876526789*99998********** PP == domain 3 score: 27.9 bits; conditional E-value: 1.7e-09 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRev.ivepqnggkpCpell...errkCneepC 52 ++Ws Ws+Cs+tC+ G + RtR+ +pq+ggk+Cp + ++ C +C FUN_001507-T1 486 GSWSLWSPCSVTCSWGNRVRTRNCnNPRPQHGGKSCPVTDrsvATQICYLGSC 538 58**********************44579********9876677788888777 PP == domain 4 score: 29.9 bits; conditional E-value: 4.2e-10 TSP1_spondin 4 seWseWseCsktCgkGvqtRtReviv.epqnggkpCpell.errkCneepC 52 s Ws Ws+C+++Cg+G++tR+R pq gg+ C + ++++C+ ++C FUN_001507-T1 545 SFWSYWSPCNSSCGTGTRTRHRICNNpTPQYGGDFCNGTViQQKNCSLKEC 595 67********************996526999*******************9 PP == domain 5 score: 21.4 bits; conditional E-value: 1.9e-07 TSP1_spondin 3 vseWseWseCsktCgkGvqtRtRevivepqnggkpCpell.errkCneepC 52 s+Ws+Ws Cs+tC+ G q R+R+ +++ g++C + + r+Cn pC FUN_001507-T1 601 WSSWSRWSVCSRTCSVGWQVRSRNC--SNHYVGQSCRGNFsDVRNCNVGPC 649 599*********************9..88899******999*********9 PP == domain 6 score: 34.8 bits; conditional E-value: 1.2e-11 TSP1_spondin 5 eWseWseCsktCgkGvqtRtReviv.epqnggkpCpell.errkCneepC 52 +W++Ws+CsktC++G++ R+R+ +p++gg+ Cp + e+ +C +C FUN_001507-T1 657 AWTSWSDCSKTCNTGSRFRNRTCSNpPPEHGGRTCPGNYyENIHCDLGSC 706 7**********************7625799*********9*****99999 PP == domain 7 score: 35.2 bits; conditional E-value: 8.9e-12 TSP1_spondin 4 seWseWseCsktCgkGvqtRtReviv.epqnggkpCpell.errkCneepC 52 ++Ws+Ws Cs+tC +G+++R+R+ +pq+gg +Cp ++ e+ Cn pC FUN_001507-T1 713 TAWSAWSGCSTTCASGTRSRRRSCSNpSPQHGGLNCPGNSsEEAYCNFGPC 763 68**********************65269***********9******9999 PP == domain 8 score: 28.7 bits; conditional E-value: 9.6e-10 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRev.ivepqnggkpCpell.errkCneepC 52 ++Ws WseCsk+CgkG+++R+R+ + p+ gg++C + + +C C FUN_001507-T1 770 TTWSLWSECSKSCGKGTKNRSRTCnNTFPRFGGRNCSGEGkQIMSCALVLC 820 78**********************6688********999889999987766 PP == domain 9 score: 33.4 bits; conditional E-value: 3.3e-11 TSP1_spondin 3 vseWseWseCsktCgkGvqtRtReviv.epqnggkpCpell.errkCneepC 52 seWs+WseCs++C++Gv+ RtR+ +p+ngg+ C+ + e + C+ +pC FUN_001507-T1 826 WSEWSKWSECSESCSTGVKFRTRTCSNpSPRNGGQGCTGDAkELEGCQPKPC 877 59***********************652689*******9999********** PP == domain 10 score: 33.9 bits; conditional E-value: 2.3e-11 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRev.ivepqnggkpCpell.errkCneepC 52 seWs+W++Cs+tCg+G+++R+R+ +p++g k C+ + +r++C ++ C FUN_001507-T1 884 SEWSNWTDCSTTCGNGTKSRHRNCeNLSPRHGEKTCTGDVyQRKHCFQQAC 934 9***********************56799*********************9 PP == domain 11 score: 19.7 bits; conditional E-value: 6.5e-07 TSP1_spondin 4 seWseWseCsktCgkGvqtRtR 25 +eWs+W++Cs+tC+ G+qtR R FUN_001507-T1 941 TEWSHWTDCSTTCDVGQQTRIR 962 79******************99 PP == domain 12 score: 25.0 bits; conditional E-value: 1.4e-08 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRevivepqnggkpCpell.errkCneepC 52 +eW++Ws+Cs+ Cg G+q+R R+ ++ +g++C +l + + C ++ C FUN_001507-T1 1003 NEWTPWSQCSSRCGFGKQHRLRNC---SAVEGDSCAGSLmQVKVCYRKYC 1049 69*********************9...8999*****9999******9999 PP == domain 13 score: 29.4 bits; conditional E-value: 5.9e-10 TSP1_spondin 4 seWseWseCsktCgkGvqtRtReviv.epqnggkpCpell.errkCneepC 52 s+Ws+W+eCs tCg Gvq++ R + +pq gg+ C + r+C ++C FUN_001507-T1 1056 SSWSAWTECSLTCGIGVQEKLRFCTNpKPQGGGDLCHGKDvTVRPCIVTRC 1106 89********************99762689999*****999******9999 PP == domain 14 score: 15.0 bits; conditional E-value: 1.9e-05 TSP1_spondin 4 seWseWseCsktCgkGvqtRtReviv 29 s+W +Ws+Cs++C++ +tRtR+ + FUN_001507-T1 1118 SSWARWSQCSANCSRRYRTRTRYCRR 1143 89********************9755 PP == domain 15 score: 22.4 bits; conditional E-value: 9.1e-08 TSP1_spondin 4 seWseWseCsktCgkGvqtRtRevivepqnggkpCpell.errkCneepC 52 ++W +W+ Csk+Cg+G ++R R+ +++ + k+C + ++++Cn+++C FUN_001507-T1 1176 NSWYSWGVCSKSCGSGLRKRVRAC--RSNTNEKNCQGDYlQTERCNTNSC 1223 58********************99..889999****9999*********9 PP == domain 16 score: -3.3 bits; conditional E-value: 9.7 TSP1_spondin 5 eWseWs.eCsktCgkGvqtRtR 25 +Ws++ +C Cg+++ t +R FUN_001507-T1 1289 TWSDYVpNCLPVCGESTLTHQR 1310 5777753699999999888777 PP >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 178.6 0.0 1.2e-55 2.1e-52 1 220 [] 1313 1554 .. 1313 1554 .. 0.93 Alignments for each domain: == domain 1 score: 178.6 bits; conditional E-value: 1.2e-55 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn......assvkvvlgehnisksegs..eqklkvekvivhpnynsdtld 86 i gg+e+++g +pwqv l++++ CGGsl+ e+wv+TAaHCv + ++v lg ++is++ ++ q+++ ++++hp++n +t+d FUN_001507-T1 1313 IFGGTESPRGLWPWQVVLTIKG-VFHCGGSLVAEDWVVTAAHCVLQrltkepLAGLRVHLGVYDISSTLEDpsIQRIDSLDIVPHPDFNWETFD 1405 789*****************99.788********************99988877888999998888776654599999999************* PP Trypsin 87 nDiallklkspvtlgdavrpiclpa..assslavgttclvsGwGntkelglsdtlqevnvpvvsreecrsayggk...vtdnmicagak.ggkd 174 D+al++l+ +++++d+vrp+clp +++++ +g+ + GwG t+++ +s+tl++vn+pvv ++ c++ay+++ vt nmicag+ ++kd FUN_001507-T1 1406 SDLALIQLQWKANVTDYVRPVCLPNkqQRRKVVPGSIGVMLGWGFTETDSPSTTLRQVNMPVVRHSSCKKAYKKDswpVTANMICAGYArRAKD 1499 *************************8778888***************************************98889*************999** PP Trypsin 175 acqGDSGGPlvcsdg.......eliGivswg.kgcasgnkpgvytrvs.syadwi 220 +c+ DSGG ++ +l Gi+swg +c+ ++k++v t ++ +++ wi FUN_001507-T1 1500 TCKQDSGGGFLFPFSknkkkkwFLGGIISWGnPQCGIPGKYSVLTDINsRFTRWI 1554 ********987655555679***************************99999998 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.0 6.8 1.1e-14 1.9e-11 2 61 .] 115 174 .. 114 174 .. 0.97 2 ! 51.7 6.8 4.6e-17 7.8e-14 2 61 .] 163 222 .. 162 222 .. 0.98 3 ! 45.2 3.0 4.9e-15 8.4e-12 2 61 .] 211 270 .. 211 270 .. 0.98 4 ! 38.4 3.9 6.3e-13 1.1e-09 2 49 .. 259 306 .. 258 318 .. 0.91 Alignments for each domain: == domain 1 score: 44.0 bits; conditional E-value: 1.1e-14 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 +++L+L sN+lt+++ +a ++l+ Lk+L+L++N+l+ ls+ +f++L +LrsL++ NrL FUN_001507-T1 115 AVEILSLYSNKLTNIPEDALRNLTELKTLNLRSNRLRLLSRTVFRDLVKLRSLNIGFNRL 174 5789******************************************************98 PP == domain 2 score: 51.7 bits; conditional E-value: 4.6e-17 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 +LrsL++ +Nrl+ l+ F +l+nL++L+L+nN l+++ ++ f++LpsL++L+L+ NrL FUN_001507-T1 163 KLRSLNIGFNRLSMLPGCLFDRLHNLQELYLNNNALKSIPEELFQNLPSLKQLYLQFNRL 222 69********************************************************98 PP == domain 3 score: 45.2 bits; conditional E-value: 4.9e-15 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 +L+ L+L++Nrl++ + ++F+g +L+ L+L nN lt+++ ++f + +sL L+L gNr+ FUN_001507-T1 211 SLKQLYLQFNRLKEFPGSTFRGTYSLQGLSLANNALTSIHVETFLNVSSLHRLNLAGNRI 270 699*******************************************************97 PP == domain 4 score: 38.4 bits; conditional E-value: 6.3e-13 LRR_8 2 nLrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLp 49 +L++L+L Nr+tsl+ F+gls L +L L nN ++t+++gaf gL+ FUN_001507-T1 259 SLHRLNLAGNRITSLSANLFRGLSLLATLELQNNFISTIHEGAFIGLK 306 89********************************************97 PP >> TSP1_ADAMTS Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 11.9 0.0007 1.2 4 55 .] 377 424 .. 373 424 .. 0.89 2 ! 14.3 9.9 3.1e-05 0.053 4 55 .] 432 479 .. 428 479 .. 0.90 3 ! 15.4 8.5 1.4e-05 0.023 6 55 .] 491 538 .. 487 538 .. 0.94 4 ! 17.6 8.6 2.8e-06 0.0049 5 55 .] 549 595 .. 544 595 .. 0.91 5 ! 12.7 12.5 9.4e-05 0.16 5 55 .] 606 649 .. 601 649 .. 0.89 6 ! 12.6 8.4 0.0001 0.18 4 55 .] 659 706 .. 655 706 .. 0.83 7 ! 13.2 9.9 6.8e-05 0.12 5 55 .] 717 763 .. 712 763 .. 0.87 8 ! 17.8 8.4 2.5e-06 0.0043 5 52 .. 774 817 .. 769 820 .. 0.79 9 ! 13.6 12.1 5e-05 0.086 4 55 .] 830 877 .. 826 877 .. 0.89 10 ! 18.4 12.3 1.6e-06 0.0027 4 55 .] 887 934 .. 883 934 .. 0.87 11 ! 13.5 8.6 5.4e-05 0.092 4 55 .] 944 996 .. 940 996 .. 0.71 12 ! 13.3 7.2 6.1e-05 0.1 4 32 .. 1006 1034 .. 1004 1049 .. 0.81 13 ! 16.9 5.9 4.6e-06 0.0078 5 55 .] 1060 1106 .. 1055 1109 .. 0.80 14 ! 10.4 7.9 0.00051 0.87 5 55 .] 1122 1172 .. 1117 1172 .. 0.89 15 ! 17.5 11.9 3.1e-06 0.0052 5 55 .] 1180 1223 .. 1175 1223 .. 0.90 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0007 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 +Ws Cs++CG+G q+ + +C++ + + e+ eC + +t++C+ +C FUN_001507-T1 377 SSWSACSVSCGNGRQESTRNCTKLTPD--EDGTECI--GRSVRTRKCQGTEC 424 48*********************9888..4799999..88899999998888 PP == domain 2 score: 14.3 bits; conditional E-value: 3.1e-05 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 +W++Cs+tC Gv R+ C++ + +s+++C+ +et+ C++++C FUN_001507-T1 432 SEWTDCSRTCSFGVAVRTRLCKRMAVG--VSNDSCE--GVSQETRVCSRQQC 479 48********************99777..589****..77899********* PP == domain 3 score: 15.4 bits; conditional E-value: 1.4e-05 TSP1_ADAMTS 6 WseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 Ws+Cs+tC G + R+ +C + + ++ ++C +++ +tq C l +C FUN_001507-T1 491 WSPCSVTCSWGNRVRTRNCNNPRPQH--GGKSCPVTDRSVATQICYLGSC 538 **********************9884..69****************9999 PP == domain 4 score: 17.6 bits; conditional E-value: 2.8e-06 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 Ws+C+ +CG+G++tR+ C + + + + ++C+ + ++++C+lk+C FUN_001507-T1 549 YWSPCNSSCGTGTRTRHRICNNPTPQ--YGGDFCN--GTVIQQKNCSLKEC 595 6**********************888..579***9..8889999*****99 PP == domain 5 score: 12.7 bits; conditional E-value: 9.4e-05 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 Ws Cs+tC G+q R+ +C ++ + ++C+ + s++++Cn pC FUN_001507-T1 606 RWSVCSRTCSVGWQVRSRNCSNHYVG-----QSCR--GNFSDVRNCNVGPC 649 8*******************999655.....7799..89999999999999 PP == domain 6 score: 12.6 bits; conditional E-value: 0.0001 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 ++Ws+CsktC +G++ R+ +C + ++ + C ++ e +C l +C FUN_001507-T1 659 TSWSDCSKTCNTGSRFRNRTCSNPPPEH--GGRTCP--GNYYENIHCDLGSC 706 69********************997763..688998..77777788888887 PP == domain 7 score: 13.2 bits; conditional E-value: 6.8e-05 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 Ws Cs+tC++G+++R+ C + + ++ +C + se+ Cn pC FUN_001507-T1 717 AWSGCSTTCASGTRSRRRSCSNPSPQH--GGLNCP--GNSSEEAYCNFGPC 763 7**********************8884..6999*9..77789999999999 PP == domain 8 score: 17.8 bits; conditional E-value: 2.5e-06 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnl 52 WseCsk+CG+G++ R+ +C ++ + ++Cs + ++ sC l FUN_001507-T1 774 LWSECSKSCGKGTKNRSRTCNNTFPR-F-GGRNCS--GEGKQIMSCAL 817 5*********************9888.3.688898..45556666665 PP == domain 9 score: 13.6 bits; conditional E-value: 5e-05 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 kWseCs++C +Gv+ R+ +C + + + + + C+ +e + C+ kpC FUN_001507-T1 830 SKWSECSESCSTGVKFRTRTCSNPSPR--NGGQGCT--GDAKELEGCQPKPC 877 59**********************988..569***9..66679999999999 PP == domain 10 score: 18.4 bits; conditional E-value: 1.6e-06 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 +W++Cs+tCG+G+++R+ +C + + ++ ++ C+ ++++C +++C FUN_001507-T1 887 SNWTDCSTTCGNGTKSRHRNCENLSPRH--GEKTCT--GDVYQRKHCFQQAC 934 59*********************98884..6999*9..66677899999999 PP == domain 11 score: 13.5 bits; conditional E-value: 5.4e-05 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkele.sdseCsaqkkPsetqsCnlkpC 55 +W++Cs+tC+ G+qtR +C ++ k++ + + + ++ ++++ C pC FUN_001507-T1 944 SHWTDCSTTCDVGQQTRIRFCNGSNCKSVGnETVNNTDITNKTDQRVCYPGPC 996 48*******************99988887532222222455566666766666 PP == domain 12 score: 13.3 bits; conditional E-value: 6.1e-05 TSP1_ADAMTS 4 gkWseCsktCGgGvqtRkvqCvqkkgkel 32 ++Ws+Cs CG G q+R +C +g++ FUN_001507-T1 1006 TPWSQCSSRCGFGKQHRLRNCSAVEGDSC 1034 69*******************99988765 PP == domain 13 score: 16.9 bits; conditional E-value: 4.6e-06 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 W+eCs tCG Gvq++ +C++ k + + C+ k ++++C +C FUN_001507-T1 1060 AWTECSLTCGIGVQEKLRFCTNPKPQG--GGDLCH--GKDVTVRPCIVTRC 1106 7*********************98885..488888..55666666666665 PP == domain 14 score: 10.4 bits; conditional E-value: 0.00051 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqs..CnlkpC 55 Ws+Cs+ C + ++tR+ C+++ + l +Cs+++ P ++qs C+ ++C FUN_001507-T1 1122 RWSQCSANCSRRYRTRTRYCRRRLNPFL--LGNCSKDTGPIQVQSgvCEMQAC 1172 7**********************99966..899*******9999655999988 PP == domain 15 score: 17.5 bits; conditional E-value: 3.1e-06 TSP1_ADAMTS 5 kWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCnlkpC 55 +W+ Csk+CG+G+++R C++++++ ++C+ + +t++Cn ++C FUN_001507-T1 1180 SWGVCSKSCGSGLRKRVRACRSNTNE-----KNCQ--GDYLQTERCNTNSC 1223 7********************99666.....7899..89999*****9999 PP >> TSP1_CFP_C CFP-like, C-terminal thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 4.6 1.3e-05 0.023 2 35 .. 370 402 .. 369 420 .. 0.86 2 ! 8.6 4.3 0.002 3.4 3 32 .. 426 454 .. 424 471 .. 0.85 3 ! 10.1 5.9 0.00073 1.2 2 37 .. 482 516 .. 481 538 .. 0.83 4 ! 19.7 3.1 7.3e-07 0.0012 2 38 .. 541 576 .. 540 590 .. 0.89 5 ! 11.0 7.0 0.00038 0.65 2 34 .. 598 629 .. 597 637 .. 0.88 6 ! 8.6 5.5 0.002 3.5 2 35 .. 652 684 .. 651 692 .. 0.87 7 ! 13.0 6.1 8.6e-05 0.15 2 36 .. 709 742 .. 708 748 .. 0.87 8 ! 19.0 4.0 1.2e-06 0.002 2 46 .. 766 809 .. 765 817 .. 0.84 9 ! 15.9 4.3 1.1e-05 0.019 2 35 .. 823 855 .. 822 861 .. 0.87 10 ! 23.2 3.7 5.9e-08 0.0001 3 41 .. 881 918 .. 879 930 .. 0.85 11 ! 15.3 1.4 1.6e-05 0.028 3 35 .. 938 969 .. 936 989 .. 0.84 12 ! 6.5 2.2 0.0092 16 6 33 .. 1003 1029 .. 998 1037 .. 0.86 13 ! 13.0 1.7 8.9e-05 0.15 2 34 .. 1052 1083 .. 1051 1089 .. 0.84 14 ! 10.3 5.2 0.00062 1.1 4 37 .. 1116 1148 .. 1113 1157 .. 0.88 15 ! 14.5 5.8 3.1e-05 0.053 3 34 .. 1173 1203 .. 1171 1212 .. 0.87 16 ? 1.3 0.0 0.4 6.8e+02 2 24 .. 1287 1307 .. 1286 1316 .. 0.71 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.3e-05 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelp 35 kg w+ews+w c +cg + + +r+c+ p FUN_001507-T1 370 KGRWTEWSSWSACSVSCGNGRQE-STRNCTKLTP 402 799***************87665.5899987766 PP == domain 2 score: 8.6 bits; conditional E-value: 0.002 TSP1_CFP_C 3 gswsewsawGlctPpcgpnptrtrqrkcka 32 sw+ ws w c +c + + +r+r ck FUN_001507-T1 426 TSWAAWSEWTDCSRTCSFG-VAVRTRLCKR 454 79**************876.6789999975 PP == domain 3 score: 10.1 bits; conditional E-value: 0.00073 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelpky 37 +g+w ws w c +c + r+r+r+c+ p++ FUN_001507-T1 482 DGAWGSWSLWSPCSVTCSWG-NRVRTRNCNNPRPQH 516 699**************875.79******9988876 PP == domain 4 score: 19.7 bits; conditional E-value: 7.3e-07 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelpkya 38 +g ws ws w c +cg++ trtr+r c+ p+y FUN_001507-T1 541 HGGWSFWSYWSPCNSSCGTG-TRTRHRICNNPTPQYG 576 689***************86.8***********9996 PP == domain 5 score: 11.0 bits; conditional E-value: 0.00038 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckael 34 +g ws ws w +c +c + ++r r+c ++ FUN_001507-T1 598 DGQWSSWSRWSVCSRTCSVG-WQVRSRNCSNHY 629 589**************876.689*****9987 PP == domain 6 score: 8.6 bits; conditional E-value: 0.002 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelp 35 +g+w w++w c +c++++ r r+r c p FUN_001507-T1 652 HGAWEAWTSWSDCSKTCNTGS-RFRNRTCSNPPP 684 699**************9875.99*****87655 PP == domain 7 score: 13.0 bits; conditional E-value: 8.6e-05 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelpk 36 +g w+ wsaw c +c + tr+r+r c p+ FUN_001507-T1 709 HGLWTAWSAWSGCSTTCA-SGTRSRRRSCSNPSPQ 742 578**************6.679*******987776 PP == domain 8 score: 19.0 bits; conditional E-value: 1.2e-06 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelpkyaktvsvveg 46 +g w+ ws w c +cg + t+ r r c+ ++p++ eg FUN_001507-T1 766 HGQWTTWSLWSECSKSCGKG-TKNRSRTCNNTFPRFGGRNCSGEG 809 589***************76.799***********9866555455 PP == domain 9 score: 15.9 bits; conditional E-value: 1.1e-05 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckaelp 35 +g wsews w c +c + ++ r+r c p FUN_001507-T1 823 HGKWSEWSKWSECSESCST-GVKFRTRTCSNPSP 855 689**************86.5899*****87655 PP == domain 10 score: 23.2 bits; conditional E-value: 5.9e-08 TSP1_CFP_C 3 gswsewsawGlctPpcgpnptrtrqrkckaelpkyaktv 41 gswsews w c +cg n t++r+r+c+ p++ +++ FUN_001507-T1 881 GSWSEWSNWTDCSTTCG-NGTKSRHRNCENLSPRHGEKT 918 8***************9.5689*******9999886654 PP == domain 11 score: 15.3 bits; conditional E-value: 1.6e-05 TSP1_CFP_C 3 gswsewsawGlctPpcgpnptrtrqrkckaelp 35 g w+ews w c +c+ + ++tr r c+ + FUN_001507-T1 938 GEWTEWSHWTDCSTTCDVG-QQTRIRFCNGSNC 969 78**************986.689****987655 PP == domain 12 score: 6.5 bits; conditional E-value: 0.0092 TSP1_CFP_C 6 sewsawGlctPpcgpnptrtrqrkckae 33 ew++w c cg + + r r+c a FUN_001507-T1 1003 NEWTPWSQCSSRCGFGK-QHRLRNCSAV 1029 79************986.579****985 PP == domain 13 score: 13.0 bits; conditional E-value: 8.9e-05 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptrtrqrkckael 34 +g ws wsaw c +cg + + + r c+ FUN_001507-T1 1052 NGGWSSWSAWTECSLTCGIGV-QEKLRFCTNPK 1083 689***************975.56788888765 PP == domain 14 score: 10.3 bits; conditional E-value: 0.00062 TSP1_CFP_C 4 swsewsawGlctPpcgpnptrtrqrkckaelpky 37 ws w+ w c +c rtr+r c+ +l + FUN_001507-T1 1116 FWSSWARWSQCSANCSR-RYRTRTRYCRRRLNPF 1148 5**************75.68*******9998876 PP == domain 15 score: 14.5 bits; conditional E-value: 3.1e-05 TSP1_CFP_C 3 gswsewsawGlctPpcgpnptrtrqrkckael 34 sw w +wG+c +cg++ r r r c+++ FUN_001507-T1 1173 ASWNSWYSWGVCSKSCGSG-LRKRVRACRSNT 1203 69***************75.799*****9765 PP == domain 16 score: 1.3 bits; conditional E-value: 0.4 TSP1_CFP_C 2 kgswsewsawGlctPpcgpnptr 24 +g+ws++ + c+P cg ++ FUN_001507-T1 1287 DGTWSDYVP--NCLPVCGESTLT 1307 578888876..699****87642 PP >> TSP1_CCN CCN3 Nov like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 14.1 0.096 1.6e+02 6 24 .. 377 397 .. 372 424 .. 0.62 2 ! 18.1 13.5 2e-06 0.0034 5 44 .] 431 479 .. 424 479 .. 0.88 3 ! 9.1 8.9 0.0013 2.2 6 28 .. 489 511 .. 486 538 .. 0.74 4 ! 11.9 6.0 0.00017 0.3 6 25 .. 548 567 .. 545 595 .. 0.78 5 ! 7.2 14.8 0.0051 8.8 6 44 .] 605 649 .. 600 649 .. 0.79 6 ! 11.1 7.3 0.0003 0.51 6 30 .. 659 679 .. 655 691 .. 0.80 7 ! 6.8 10.4 0.0068 12 6 25 .. 716 735 .. 712 763 .. 0.76 8 ! 14.0 6.9 3.7e-05 0.063 6 27 .. 773 794 .. 767 798 .. 0.83 9 ! 11.8 9.8 0.00018 0.31 6 25 .. 830 849 .. 825 877 .. 0.68 10 ! 13.9 9.7 4.2e-05 0.071 6 26 .. 887 915 .. 883 934 .. 0.70 11 ! 15.6 11.1 1.2e-05 0.021 6 44 .] 944 996 .. 940 996 .. 0.84 12 ! 15.5 8.5 1.3e-05 0.022 4 44 .] 1004 1049 .. 1002 1049 .. 0.80 13 ! 12.5 5.3 0.00011 0.19 6 23 .. 1059 1076 .. 1055 1106 .. 0.81 14 ? 1.5 8.4 0.3 5.2e+02 6 31 .. 1121 1142 .. 1118 1146 .. 0.75 15 ! 9.3 14.3 0.0011 1.9 6 40 .. 1179 1209 .. 1172 1223 .. 0.77 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.096 TSP1_CCN 6 teWsaCSktCGlGv..stRvs 24 ++WsaCS +CG G stR FUN_001507-T1 377 SSWSACSVSCGNGRqeSTRNC 397 89***********62255543 PP == domain 2 score: 18.1 bits; conditional E-value: 2e-06 TSP1_CCN 5 steWsaCSktCGlGvstRvsn........dneeCk.leketrlCqlrpC 44 +eW++CS+tC +Gv++R++ +n++C+ ++etr+C ++C FUN_001507-T1 431 WSEWTDCSRTCSFGVAVRTRLckrmavgvSNDSCEgVSQETRVCSRQQC 479 489***************99778899999*****945799*****9999 PP == domain 3 score: 9.1 bits; conditional E-value: 0.0013 TSP1_CCN 6 teWsaCSktCGlGvstRvsndne 28 + Ws+CS tC G +R++n n+ FUN_001507-T1 489 SLWSPCSVTCSWGNRVRTRNCNN 511 67****************98443 PP == domain 4 score: 11.9 bits; conditional E-value: 0.00017 TSP1_CCN 6 teWsaCSktCGlGvstRvsn 25 + Ws+C ++CG+G+ tR + FUN_001507-T1 548 SYWSPCNSSCGTGTRTRHRI 567 67*************99873 PP == domain 5 score: 7.2 bits; conditional E-value: 0.0051 TSP1_CCN 6 teWsaCSktCGlGvstRvsn.....dneeCkle.ketrlCqlrpC 44 ++Ws CS+tC +G +R +n ++C+ + ++ r C++ pC FUN_001507-T1 605 SRWSVCSRTCSVGWQVRSRNcsnhyVGQSCRGNfSDVRNCNVGPC 649 89***************9986544444689854378899999999 PP == domain 6 score: 11.1 bits; conditional E-value: 0.0003 TSP1_CCN 6 teWsaCSktCGlGvstRvsndneeC 30 t+Ws+CSktC +G R + +C FUN_001507-T1 659 TSWSDCSKTCNTGSRFRNR----TC 679 89***********877754....44 PP == domain 7 score: 6.8 bits; conditional E-value: 0.0068 TSP1_CCN 6 teWsaCSktCGlGvstRvsn 25 ++Ws CS+tC G+ +R ++ FUN_001507-T1 716 SAWSGCSTTCASGTRSRRRS 735 89***********9888764 PP == domain 8 score: 14.0 bits; conditional E-value: 3.7e-05 TSP1_CCN 6 teWsaCSktCGlGvstRvsndn 27 + Ws+CSk+CG G++ R ++ n FUN_001507-T1 773 SLWSECSKSCGKGTKNRSRTCN 794 67*************9987544 PP == domain 9 score: 11.8 bits; conditional E-value: 0.00018 TSP1_CCN 6 teWsaCSktCGlGvstRvsn 25 ++Ws+CS++C +Gv+ R+++ FUN_001507-T1 830 SKWSECSESCSTGVKFRTRT 849 89***************985 PP == domain 10 score: 13.9 bits; conditional E-value: 4.2e-05 TSP1_CCN 6 teWsaCSktCGlGvstRvsn........d 26 ++W++CS+tCG G+++R +n FUN_001507-T1 887 SNWTDCSTTCGNGTKSRHRNcenlsprhG 915 89***************997444444333 PP == domain 11 score: 15.6 bits; conditional E-value: 1.2e-05 TSP1_CCN 6 teWsaCSktCGlGvstRvsn..............dneeCkleketrlCqlrpC 44 ++W++CS+tC++G tR++ +n+ ++++++r+C+ pC FUN_001507-T1 944 SHWTDCSTTCDVGQQTRIRFcngsncksvgnetvNNTDITNKTDQRVCYPGPC 996 89****************95557778888888888888888899999999888 PP == domain 12 score: 15.5 bits; conditional E-value: 1.3e-05 TSP1_CCN 4 qsteWsaCSktCGlGvstRvsn....dneeCk.leketrlCqlrpC 44 + t Ws+CS+ CG+G +R++n + ++C+ + + ++C+ + C FUN_001507-T1 1004 EWTPWSQCSSRCGFGKQHRLRNcsavEGDSCAgSLMQVKVCYRKYC 1049 4599*****************9766667788734578888888777 PP == domain 13 score: 12.5 bits; conditional E-value: 0.00011 TSP1_CCN 6 teWsaCSktCGlGvstRv 23 ++W++CS tCG+Gv + FUN_001507-T1 1059 SAWTECSLTCGIGVQEKL 1076 89***********97655 PP == domain 14 score: 1.5 bits; conditional E-value: 0.3 TSP1_CCN 6 teWsaCSktCGlGvstRvsndneeCk 31 +Ws+CS++C s R++++ + C+ FUN_001507-T1 1121 ARWSQCSANC----SRRYRTRTRYCR 1142 58********....566666666776 PP == domain 15 score: 9.3 bits; conditional E-value: 0.0011 TSP1_CCN 6 teWsaCSktCGlGvstRvsndneeCkleketrlCq 40 +W CSk+CG G+ Rv+ C+++++++ Cq FUN_001507-T1 1179 YSWGVCSKSCGSGLRKRVR----ACRSNTNEKNCQ 1209 48****************7....777777777776 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 4.9 6e-07 0.001 2 37 .. 115 151 .. 114 155 .. 0.86 2 ! 16.2 2.6 7.9e-06 0.013 1 38 [. 138 176 .. 138 181 .. 0.87 3 ! 24.0 3.9 2.7e-08 4.5e-05 2 40 .. 163 202 .. 162 211 .. 0.86 4 ! 33.4 2.5 3e-11 5.1e-08 2 40 .. 187 226 .. 186 232 .. 0.89 5 ! 20.5 1.7 3.5e-07 0.0006 2 40 .. 235 274 .. 234 276 .. 0.90 6 ! 19.7 2.7 6.3e-07 0.0011 2 39 .. 259 297 .. 258 301 .. 0.92 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 6e-07 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkit 37 +e L+L +N++t+i++ l++L+ L+tL+L +N +++ FUN_001507-T1 115 AVEILSLYSNKLTNIPEdaLRNLTELKTLNLRSN-RLR 151 5789*************99889*********555.775 PP == domain 2 score: 16.2 bits; conditional E-value: 7.9e-06 LRR_4 1 pnLetLdLsnNritdidp..lskLpnLetLdLsgNnkitd 38 + L+tL+L++Nr+ ++ +++L +L++L++ g n+++ FUN_001507-T1 138 TELKTLNLRSNRLRLLSRtvFRDLVKLRSLNI-GFNRLSM 176 67************999988889*********.7778865 PP == domain 3 score: 24.0 bits; conditional E-value: 2.7e-08 LRR_4 2 nLetLdLsnNritdidp.lsk.LpnLetLdLsgNnkitdls 40 +L++L++ Nr++ +++ l + L+nL++L+L +Nn +++++ FUN_001507-T1 163 KLRSLNIGFNRLSMLPGcLFDrLHNLQELYL-NNNALKSIP 202 7****************74445*********.888999994 PP == domain 4 score: 33.4 bits; conditional E-value: 3e-11 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitdls 40 nL++L+L+nN +++i++ +++Lp+L++L+L + n++++++ FUN_001507-T1 187 NLQELYLNNNALKSIPEelFQNLPSLKQLYL-QFNRLKEFP 226 9****************97778*********.666998875 PP == domain 5 score: 20.5 bits; conditional E-value: 3.5e-07 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitdls 40 +L+ L+L+nN +t+i + + +L+ L+L+gN +it+ls FUN_001507-T1 235 SLQGLSLANNALTSIHVetFLNVSSLHRLNLAGN-RITSLS 274 79***************87446*********999.**9997 PP == domain 6 score: 19.7 bits; conditional E-value: 6.3e-07 LRR_4 2 nLetLdLsnNritdidp..lskLpnLetLdLsgNnkitdl 39 +L++L+L++Nrit+++ +++L L tL L +Nn i+++ FUN_001507-T1 259 SLHRLNLAGNRITSLSAnlFRGLSLLATLEL-QNNFISTI 297 89****************8779*********.999**998 PP >> LRR_5 BspA type Leucine rich repeat region (6 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.9 0.0 2.1e-11 3.6e-08 19 126 .. 123 236 .. 116 237 .. 0.92 2 ! 35.0 0.2 9.1e-12 1.6e-08 1 100 [. 199 304 .. 199 312 .. 0.88 Alignments for each domain: == domain 1 score: 33.9 bits; conditional E-value: 2.1e-11 LRR_5 19 pssltsIgeyaFsnctslksitlpss.ltsigsyaFsnc.slesitip.ssltsigeyaFsncsnlksitlpen.ltsigssaFsnc.slksitip 109 +++lt+I e a +n t+lk+++l s+ l+ +++ +F + +l+s++i + l+ ++ F +nl+++ l++n l+si ++ F+n slk+++++ FUN_001507-T1 123 SNKLTNIPEDALRNLTELKTLNLRSNrLRLLSRTVFRDLvKLRSLNIGfNRLSMLPGCLFDRLHNLQELYLNNNaLKSIPEELFQNLpSLKQLYLQ 218 589********************8866***********99*******8569********************9988***********99******99 PP LRR_5 110 .ssvtkigeyaFsncsnl 126 + ++++ ++F+++++l FUN_001507-T1 219 fNRLKEFPGSTFRGTYSL 236 669999999999998776 PP == domain 2 score: 35.0 bits; conditional E-value: 9.1e-12 LRR_5 1 tsIgsyaFync.slesitip.ssltsIgeyaFsnctslksitlpss.ltsigsyaFsnc.slesitips.sltsigeyaFsncsnlksitlpen.l 90 +sI+++ F+n sl+++ ++ + l++ ++F+++ sl+ ++l ++ ltsi ++F n sl ++++ +ts++ + F++ s l +++l++n + FUN_001507-T1 199 KSIPEELFQNLpSLKQLYLQfNRLKEFPGSTFRGTYSLQGLSLANNaLTSIHVETFLNVsSLHRLNLAGnRITSLSANLFRGLSLLATLELQNNfI 294 589999999999999999997789999999999999999999988669999999999988999999985489999999999999999999999988 PP LRR_5 91 tsigssaFsn 100 ++i + aF + FUN_001507-T1 295 STIHEGAFIG 304 9999999965 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.1 0.026 45 3 23 .] 117 137 .. 115 137 .. 0.88 2 ? 5.0 0.2 0.035 59 2 17 .. 140 155 .. 139 161 .. 0.76 3 ? 4.9 0.2 0.038 64 1 20 [. 163 181 .. 163 185 .. 0.77 4 ! 10.1 0.7 0.0007 1.2 1 23 [] 187 209 .. 187 209 .. 0.83 5 ? 4.3 0.0 0.063 1.1e+02 1 19 [. 211 229 .. 211 232 .. 0.78 6 ? 4.1 0.1 0.071 1.2e+02 1 21 [. 235 255 .. 235 257 .. 0.87 7 ! 7.7 0.3 0.0043 7.4 1 23 [] 259 281 .. 259 281 .. 0.88 8 ? 1.8 0.1 0.42 7.2e+02 2 20 .. 284 302 .. 283 305 .. 0.80 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.026 LRR_1 3 eeLdLsnNnlsgllpeslgnl 23 e+L+L +N+l+ ++ ++l+nl FUN_001507-T1 117 EILSLYSNKLTNIPEDALRNL 137 89********99999999887 PP == domain 2 score: 5.0 bits; conditional E-value: 0.035 LRR_1 2 LeeLdLsnNnlsgllp 17 L++L+L++N+l l+ FUN_001507-T1 140 LKTLNLRSNRLRLLSR 155 9**********75544 PP == domain 3 score: 4.9 bits; conditional E-value: 0.038 LRR_1 1 nLeeLdLsnNnlsgllpesl 20 +L++L++ N+ls lp +l FUN_001507-T1 163 KLRSLNIGFNRLS-MLPGCL 181 69**********8.555444 PP == domain 4 score: 10.1 bits; conditional E-value: 0.0007 LRR_1 1 nLeeLdLsnNnlsgllpeslgnl 23 nL+eL+L+nN l +++ e ++nl FUN_001507-T1 187 NLQELYLNNNALKSIPEELFQNL 209 8***********86777777765 PP == domain 5 score: 4.3 bits; conditional E-value: 0.063 LRR_1 1 nLeeLdLsnNnlsgllpes 19 +L+ L+L+ N+l + + ++ FUN_001507-T1 211 SLKQLYLQFNRLKEFPGST 229 79**********7555555 PP == domain 6 score: 4.1 bits; conditional E-value: 0.071 LRR_1 1 nLeeLdLsnNnlsgllpeslg 21 +L+ L+L+nN l++++ e++ FUN_001507-T1 235 SLQGLSLANNALTSIHVETFL 255 6999********999988875 PP == domain 7 score: 7.7 bits; conditional E-value: 0.0043 LRR_1 1 nLeeLdLsnNnlsgllpeslgnl 23 +L +L+L++N++++l+ + +++l FUN_001507-T1 259 SLHRLNLAGNRITSLSANLFRGL 281 699*********99999888876 PP == domain 8 score: 1.8 bits; conditional E-value: 0.42 LRR_1 2 LeeLdLsnNnlsgllpesl 20 L +L L+nN +s+++ ++ FUN_001507-T1 284 LATLELQNNFISTIHEGAF 302 668********98877776 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.1 2.6e-07 0.00045 1 102 [. 1324 1434 .. 1324 1445 .. 0.73 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 2.6e-07 DUF1986 1 wPwladvyleGdlicsGvlidkswvlvsesclsdvdleh...syvsvvlGgaktkksvkgpyeqivrvdafkdvpk.........sevvllhlk 82 wPw + ++G++ c G l+ +wv+ c+ + l + + v lG +++ p i+r+d+ + vp+ s++ l+ l+ FUN_001507-T1 1324 WPWQVVLTIKGVFHCGGSLVAEDWVVTAAHCVLQR-LTKeplAGLRVHLGVYDISSTLEDP--SIQRIDSLDIVPHpdfnwetfdSDLALIQLQ 1414 9***************************9998653.3340114566777777766666666..46677766666532222222228999***** PP DUF1986 83 skvsfsrhvlPtfvpesrne 102 k++ + +v+P+ +p+ +++ FUN_001507-T1 1415 WKANVTDYVRPVCLPNKQQR 1434 ***************96554 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 1.7 0.092 1.6e+02 66 120 .. 116 169 .. 101 179 .. 0.69 2 ! 16.4 0.3 4.1e-06 0.0069 60 126 .. 182 247 .. 171 251 .. 0.90 3 ? 3.7 0.8 0.034 58 57 113 .. 251 306 .. 239 327 .. 0.77 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.092 LRR_9 66 lktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslkkltslsl 120 ++ l+l +n++++i e+ + l +l++l l +n+l+ l+ + +l kl sl + FUN_001507-T1 116 VEILSLYSNKLTNIPEDALRNLTELKTLNLRSNRLRLLSR-TVFRDLVKLRSLNI 169 5667788888888888888888888888888888877765.45555555555554 PP == domain 2 score: 16.4 bits; conditional E-value: 4.1e-06 LRR_9 60 fPllkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslkkltslsllrnpvt 126 f l+ l+ l+lnnn + i e+l + lP+l++l l n+l+e+ + +l+ lsl +n++t FUN_001507-T1 182 FDRLHNLQELYLNNNALKSIPEELFQNLPSLKQLYLQFNRLKEFPG-STFRGTYSLQGLSLANNALT 247 556889999**********************************998.88999999999999999887 PP == domain 3 score: 3.7 bits; conditional E-value: 0.034 LRR_9 57 ldgfPllkrlktlllnnnrilrigegleevlPnleeliltknslqeladldPlaslk 113 ++ f + l+ l l nri+ ++ +l + l l +l l +n ++ + + ++ lk FUN_001507-T1 251 VETFLNVSSLHRLNLAGNRITSLSANLFRGLSLLATLELQNNFISTIHE-GAFIGLK 306 5667777889999999999999999999999999999999999988877.5555555 PP >> LRR_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, LRR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 2.0 0.0013 2.2 14 96 .. 160 244 .. 148 250 .. 0.76 2 ? 9.9 0.5 0.00045 0.76 18 133 .. 236 354 .. 213 363 .. 0.76 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0013 LRR_LRWD1 14 rlgkiqslnlsglellsehldpnllgrlkklkeldlsnnlletlpanl..glshlrilrctnnqlgdv..ttlhqfpeleelslegn 96 l k++sln+ g++ ls l l+ rl++l+el l nn l+++p +l l l+ l n+l + +t+ l+ lsl n FUN_001507-T1 160 DLVKLRSLNI-GFNRLS-MLPGCLFDRLHNLQELYLNNNALKSIPEELfqNLPSLKQLYLQFNRLKEFpgSTFRGTYSLQGLSLANN 244 5789999998.777777.588899*********************998445777888888888877653356666666777776666 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00045 LRR_LRWD1 18 iqslnlsglellsehldpnllgrlkklkeldlsnnlletlpanl..glshlrilrctnnqlgdvttlhqfpelee...lslegnpfltvsdn.lkv 107 +q l l+ l s h++ l + l+ l+l+ n + +l anl gls l l nn + + f l+ + l+gnpf + FUN_001507-T1 236 LQGLSLANNALTSIHVETFL--NVSSLHRLNLAGNRITSLSANLfrGLSLLATLELQNNFISTIHEG-AFIGLKTgifVLLNGNPFYCDCQLrWLK 328 67888888888888888766..578999***************988999999999999987655432.45566543336799****9876541334 PP LRR_LRWD1 108 sfllpklrkvngkdtastcsqvesld 133 +++ k + + +tcsq + l FUN_001507-T1 329 AWITRKTKYIHSSRLRTTCSQPDHLK 354 67788888899999999999988775 PP >> LRRCT Leucine rich repeat C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.1 3.4e-05 0.058 2 26 .] 345 369 .. 344 369 .. 0.95 2 ? -1.3 0.1 3.9 6.6e+03 3 12 .. 849 858 .. 849 860 .. 0.87 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 3.4e-05 LRRCT 2 arCasPeslrGqplldllpsdfsCs 26 ++C++P++l+++pl+ ++++ f C+ FUN_001507-T1 345 TTCSQPDHLKNRPLIYVTDDQFRCE 369 79**********************6 PP == domain 2 score: -1.3 bits; conditional E-value: 3.9 LRRCT 3 rCasPeslrG 12 +C+ P+++ G FUN_001507-T1 849 TCSNPSPRNG 858 7******998 PP >> LRR_NXF1-5 NXF1/2/3/5 leucine-rich repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 6.3 0.047 79 46 115 .. 135 202 .. 123 222 .. 0.77 2 ? 5.5 1.7 0.01 17 49 126 .. 186 261 .. 181 266 .. 0.87 3 ? 0.9 0.2 0.27 4.5e+02 47 92 .. 256 299 .. 240 321 .. 0.71 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.047 LRR_NXF1-5 46 enipeLlsLnlsnnklykLdglsdivqkapnlkiLnLsknelksereLdkvkglkleeLwlegNpLcdtF 115 +n++eL +Lnl++n+l L +++ + +l++Ln+ n+l+ + +l+eL+l++N L + FUN_001507-T1 135 RNLTELKTLNLRSNRLRLLS--RTVFRDLVKLRSLNIGFNRLSMLPGCLFDRLHNLQELYLNNNALKSIP 202 58899999999999988887..468889999**********99876544444456789999999997755 PP == domain 2 score: 5.5 bits; conditional E-value: 0.01 LRR_NXF1-5 49 peLlsLnlsnnklykLdglsdivqkapnlkiLnLsknelksereLdkvkglkleeLwlegNpLcdtFkdqstyisair 126 +L +L l+nn l ++ +++ q+ p+lk+L L n+lk+ + l+ L l +N L + ++ ++s+++ FUN_001507-T1 186 HNLQELYLNNNALKSIP--EELFQNLPSLKQLYLQFNRLKEFPGSTFRGTYSLQGLSLANNALTSIHVETFLNVSSLH 261 56888888888887776..59*******************999888888899************99999999999876 PP == domain 3 score: 0.9 bits; conditional E-value: 0.27 LRR_NXF1-5 47 nipeLlsLnlsnnklykLdglsdivqkapnlkiLnLsknelksere 92 n++ L Lnl n++++L +++ + + l +L+L +n +++ +e FUN_001507-T1 256 NVSSLHRLNLAGNRITSLS--ANLFRGLSLLATLELQNNFISTIHE 299 6778888888888888887..5777888888888888887777666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1560 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 780 (0.0305344); expected 510.9 (0.02) Passed bias filter: 314 (0.012292); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.49u 0.39s 00:00:00.88 Elapsed: 00:00:00.42 # Mc/sec: 14822.05 // Query: FUN_001508-T1 [L=577] Description: FUN_001508 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-40 137.2 2.0 1.9e-22 80.5 0.1 2.5 2 DUF5918 Family of unknown function (DUF5918) 5.6e-17 62.1 0.1 1.3e-16 60.9 0.1 1.7 1 U-box U-box domain 3.2e-06 27.5 8.5 0.046 14.2 10.0 3.4 2 zf-RING_UBOX RING-type zinc-finger 6.8e-05 23.2 12.3 0.00022 21.6 12.3 2.0 1 zf-RING_5 zinc-RING finger domain 0.0012 19.1 9.3 0.0012 19.1 9.3 2.4 2 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 0.0015 18.7 7.1 0.0032 17.7 7.1 1.6 1 zf-RING_4 RING/Ubox like zinc-binding domain 0.0049 17.2 8.6 0.022 15.2 8.6 2.2 1 Prok-RING_4 Prokaryotic RING finger family 4 0.0071 17.1 9.2 0.024 15.4 9.2 2.0 1 zf-RING_2 Ring finger domain ------ inclusion threshold ------ 1.1 9.5 6.5 2.6 8.2 6.5 1.7 1 zf-RING_16 RING/Ubox like zinc-binding domain 1.1 9.9 12.7 2 9.1 10.4 2.5 2 zf-RING_10 zinc RING finger of MSL2 1.4 9.3 10.9 0.9 9.9 8.1 2.3 2 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 1.7 9.8 5.6 2.5 9.2 2.3 3.1 2 zf-C2H2 Zinc finger, C2H2 type 3.4 8.2 6.4 39 4.8 0.3 3.6 3 zf-C2H2_ZN142 ZN142 C2H2 zinc finger 4.6 7.9 10.2 9.9 6.9 9.0 2.3 2 zf-C3HC4_4 zinc finger of C3HC4-type, RING Domain annotation for each model (and alignments): >> DUF5918 Family of unknown function (DUF5918) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.5 0.1 1e-25 1.9e-22 1 86 [. 2 87 .. 2 120 .. 0.85 2 ! 55.6 0.4 4.3e-18 7.8e-15 98 210 .. 144 254 .. 112 255 .. 0.86 Alignments for each domain: == domain 1 score: 80.5 bits; conditional E-value: 1e-25 DUF5918 1 nlclpqfktriscnkvsaDgYeveNLlsedlakrrrGFkaeyFikPPveitlsfpfpieieridvelkvggqaskgleiftssdsk 86 n+ +p f+++++c+ v++DgY+++NL+s d ++r+rGF+a+yFik P + +++pfp +e+ ++++kvg q+s+g+ ++++ FUN_001508-T1 2 NFLHPFFNPKVECDVVCSDGYSISNLVSLDFRERSRGFLAAYFIKSPALLLFQLPFPAHVESMVIKPKVGCQISSGISVSVAGIAT 87 999*****************************************************************************976665 PP == domain 2 score: 55.6 bits; conditional E-value: 4.3e-18 DUF5918 98 skseekfeeeeefklvgrvelkeetkvvfvnrafrsrppfeskppskpaeasqeelwsrglesLsaVthlkvrvlktgagsvlaikaLevwGqPar 193 + s+ k e+++ f++v+ + ke + v + n+ f++r + + ++ ++ + e+++ +++L++Vth+ +++ + +++sv+ai+++e+wGqP+ FUN_001508-T1 144 TPSSAKCEHSSLFTQVAWLNDKEGKTVRIENKLFQHRLARQGLQVPQTQDIQL-EVFQ-RPSCLQKVTHVVLKIARLSGSSVPAIGKVEIWGQPSI 237 45566788999***************************988877777776666.5555.59*********************************** PP DUF5918 194 scpaelvekilkvleks 210 c++e++e l ++ek+ FUN_001508-T1 238 YCKPEILEYALSIQEKI 254 ********999998876 PP >> U-box U-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.9 0.1 7.4e-20 1.3e-16 1 69 [. 292 366 .. 292 369 .. 0.96 Alignments for each domain: == domain 1 score: 60.9 bits; conditional E-value: 7.4e-20 U-box 1 iPdefldpitlelmkdPvilpsgvtvdrstierhlls.....kdktdPft.repltqdqlipnlelKekIdafle 69 iP+ fld+it+elm+ P +lpsg+++d t+e+h+ + ++dPft + + + ++ +pn++lK +Id+fl FUN_001508-T1 292 IPEDFLDQITYELMTVPLLLPSGHNIDTVTLEKHIAVerswgRMPSDPFTgKIFSDTSKPVPNSALKVRIDKFLL 366 8**********************************98889999*******99999******************96 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.0 0.0023 4.3 3 22 .. 300 319 .. 299 333 .. 0.81 2 ! 14.2 10.0 2.5e-05 0.046 1 29 [. 522 555 .. 522 567 .. 0.68 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0023 zf-RING_UBOX 3 ICleeftdPlvlpCGHtfCr 22 I +e++t Pl+lp GH++ FUN_001508-T1 300 ITYELMTVPLLLPSGHNIDT 319 99*******557****9865 PP == domain 2 score: 14.2 bits; conditional E-value: 2.5e-05 zf-RING_UBOX 1 CpICleeftdP.lv.lpCGHtfCreCl...wels 29 C C+ ++++ + lpC+H++Cr+Cl +++ FUN_001508-T1 522 CVSCKRDLSETsIFlLPCQHIICRSCLlnvRQQE 555 6679999996653425***********5332222 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 12.3 1.2e-07 0.00022 2 42 .. 522 563 .. 521 565 .. 0.95 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.2e-07 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll..eerqCpiCk 42 C +C ++l ++ ++l++C+Hi+C +Cl + e+ +C Ck FUN_001508-T1 522 CVSCKRDL-SETSIFLLPCQHIICRSCLLNVRqqEDSVCKECK 563 9*******.999*******************999999999998 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.2 1.8 3.3e+03 10 20 .. 144 153 .. 136 154 .. 0.77 2 ! 19.1 9.3 6.6e-07 0.0012 1 40 [] 522 562 .. 522 562 .. 0.95 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.8 zf-C3HC4 10 epvtllpCgHs 20 +p+ +++C Hs FUN_001508-T1 144 TPS-SAKCEHS 153 566.899***7 PP == domain 2 score: 19.1 bits; conditional E-value: 6.6e-07 zf-C3HC4 1 CpiCleelkepv.tllpCgHsfCssCiksllesnnvkCplC 40 C C+ l+e++ +llpC+H C+sC+ ++ +++ + C +C FUN_001508-T1 522 CVSCKRDLSETSiFLLPCQHIICRSCLLNVRQQEDSVCKEC 562 899*****9999899*****************99999**99 PP >> zf-RING_4 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 7.1 1.8e-06 0.0032 4 48 .] 522 567 .. 519 567 .. 0.83 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 1.8e-06 zf-RING_4 4 Cdekl.detdkdllPCeCgyqiClfCyedileeeegrCPgCreeYk 48 C++ d ++++++ +C++ iC+ C +++++e+ +C C+ ++k FUN_001508-T1 522 CVSCKrDLSETSIFLLPCQHIICRSCLLNVRQQEDSVCKECKCKFK 567 6655557777777777789***********************8875 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 8.6 1.2e-05 0.022 1 26 [. 522 549 .. 522 570 .. 0.80 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.2e-05 Prok-RING_4 1 Cvlcgre..etkivlspCgHlvCkeCfd 26 Cv c+r et i l pC H++C++C FUN_001508-T1 522 CVSCKRDlsETSIFLLPCQHIICRSCLL 549 999*998889****************64 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 9.2 1.3e-05 0.024 3 43 .. 522 562 .. 520 563 .. 0.82 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.3e-05 zf-RING_2 3 CpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst.CPlC 43 C+ C ++l +e ++ lpC+H+++++Cl ++ +++ + C C FUN_001508-T1 522 CVSCKRDL-SETSIFLLPCQHIICRSCLLNVRQQEDSvCKEC 562 999*9999.66777889*************766666689877 PP >> zf-RING_16 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 6.5 0.0014 2.6 6 52 .. 521 565 .. 516 570 .. 0.85 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0014 zf-RING_16 6 kCayCelavkgrlflcgvCeHvlHasCareWfenddlaeCpsGCGck 52 C+ C+ + ++ C+H++ sC+ + +++d ++C C ck FUN_001508-T1 521 LCVSCKRDLSETSIFLLPCQHIICRSCLLNVRQQED-SVCKE-CKCK 565 6*****************************999999.77764.5444 PP >> zf-RING_10 zinc RING finger of MSL2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 1.1 1.9e+03 29 46 .. 136 153 .. 130 162 .. 0.59 2 ? 9.1 10.4 0.0011 2 2 45 .. 521 564 .. 520 575 .. 0.74 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.1 zf-RING_10 29 CvgkkkklkpsCskCkdy 46 C + ++ps +kC+ FUN_001508-T1 136 CHSYNLDITPSSAKCEHS 153 444444455555555544 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0011 zf-RING_10 2 sCvvCgkLLvdPltpkeseCqHyvCrlCvgk.kkklkpsCskCkd 45 Cv C + L + CqH +Cr+C+ + +++ + C++Ck+ FUN_001508-T1 521 LCVSCKRDLSETSIF-LLPCQHIICRSCLLNvRQQEDSVCKECKC 564 588888888876554.678*********85527788899****95 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 4.4 8e+03 14 21 .. 146 153 .. 143 154 .. 0.77 2 ? 9.9 8.1 0.00049 0.9 2 38 .. 522 560 .. 521 563 .. 0.78 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 4.4 zf-C3HC4_2 14 vvtpCgHv 21 +++C H+ FUN_001508-T1 146 SSAKCEHS 153 5689**97 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00049 zf-C3HC4_2 2 CpiCldmlkdplvvt.pCgHvfCqkCilraLeesn.eCP 38 C C+ l++++ pC+H C++C+l ++++ C FUN_001508-T1 522 CVSCKRDLSETSIFLlPCQHIICRSCLLNVRQQEDsVCK 560 7779988988865546************98777765675 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 2.8 5.1e+03 5 13 .. 426 434 .. 425 435 .. 0.85 2 ? 9.2 2.3 0.0014 2.5 2 19 .. 558 575 .. 557 577 .] 0.93 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 2.8 zf-C2H2 5 dCgksFsrk 13 +C+++F ++ FUN_001508-T1 426 KCDQRFVTS 434 7*****986 PP == domain 2 score: 9.2 bits; conditional E-value: 0.0014 zf-C2H2 2 kCpdCgksFsrksnLkrH 19 +C++C+ +F++++ L+ H FUN_001508-T1 558 VCKECKCKFKQSDVLRVH 575 6***************** PP >> zf-C2H2_ZN142 ZN142 C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.15 2.8e+02 14 21 .. 174 181 .. 169 183 .. 0.84 2 ? 2.1 0.1 0.15 2.8e+02 4 13 .. 425 434 .. 423 435 .. 0.89 3 ? 4.8 0.3 0.021 39 3 19 .. 559 575 .. 558 577 .] 0.92 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.15 zf-C2H2_ZN142 14 skLrlHkr 21 kL++H++ FUN_001508-T1 174 NKLFQHRL 181 69*****8 PP == domain 2 score: 2.1 bits; conditional E-value: 0.15 zf-C2H2_ZN142 4 adCdfttksn 13 + Cd+++ ++ FUN_001508-T1 425 GKCDQRFVTS 434 68*****987 PP == domain 3 score: 4.8 bits; conditional E-value: 0.021 zf-C2H2_ZN142 3 CadCdfttksnskLrlH 19 C C +k++ Lr H FUN_001508-T1 559 CKECKCKFKQSDVLRVH 575 999************** PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 8.4 1.5e+04 11 19 .. 145 153 .. 141 155 .. 0.84 2 ? 6.9 9.0 0.0054 9.9 14 42 .] 537 562 .. 522 564 .. 0.89 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 8.4 zf-C3HC4_4 11 PvsieCGhs 19 P s C+hs FUN_001508-T1 145 PSSAKCEHS 153 78889*997 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0054 zf-C3HC4_4 14 ieCGhsfClsCisslqkepdgesllCplC 42 ++C h++C+sC+ ++ +++d++ C +C FUN_001508-T1 537 LPCQHIICRSCLLNVRQQEDSV---CKEC 562 89***************99995...7777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (577 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 959 (0.0375416); expected 510.9 (0.02) Passed bias filter: 515 (0.0201605); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.36u 0.36s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 5692.38 // Query: FUN_001509-T1 [L=361] Description: FUN_001509 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-09 37.8 0.0 5.5e-09 36.6 0.0 1.6 2 FIST FIST N domain 1.5e-05 25.6 0.0 5.2e-05 23.9 0.0 1.8 2 FIST_C FIST C domain 0.00067 19.9 0.3 0.0013 18.9 0.3 1.5 1 F-box-like F-box-like 0.0017 18.7 0.0 0.0035 17.7 0.0 1.6 1 F-box F-box domain Domain annotation for each model (and alignments): >> FIST FIST N domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.6 0.0 8.7e-13 5.5e-09 9 164 .. 92 252 .. 81 257 .. 0.67 2 ? -3.3 0.0 1.6 1e+04 20 32 .. 303 315 .. 285 327 .. 0.65 Alignments for each domain: == domain 1 score: 36.6 bits; conditional E-value: 8.7e-13 FIST 9 aea.dleellealreafp.gapviGcstaGeias.....egvledsvvalal...afasfevataliedssadsreageelakal.....sppkll 89 ++ ++ +l+ +++ +p g+p iGc++ G+++s ++++e+s + + +++e++ +++ + ++ + + + + p kl+ FUN_001509-T1 92 SSTvRIKSFLRSIQKCLPlGCPFIGCTGHGVVGSgmsssRNQSENSQGLSLMmfpRCERLEIHDFYVPLR--NKYKKISGVKS-FlpdmtLPVKLV 184 234588899***********************66677764446666444444114444444444444432..33333333333.12444656778* PP FIST 90 llladglssne.eellegldsalgeggvpivGGlAgdglrfektyvlangevlsdgvvavalygdalkvgvgvsqg 164 ++la +ls l+ +l s +g+ +v+ivG +d+ ++n ev+ + ++++++ g+ + ++++++g FUN_001509-T1 185 IVLAHPLSLGKlTHLTVALRSKYGD-SVVIVGA-YSDNY------LFYNSEVTYREIIGLVFAGNLQATSTVITGG 252 ****999876548999999999997.9******.77765......5599**999***********55555555555 PP == domain 2 score: -3.3 bits; conditional E-value: 1.6 FIST 20 lreafpgapviGc 32 l++a+pg+ v G FUN_001509-T1 303 LKDALPGTAVAGF 315 5566666666553 PP >> FIST_C FIST C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 0.76 4.8e+03 107 126 .. 100 119 .. 75 123 .. 0.78 2 ! 23.9 0.0 8.1e-09 5.2e-05 48 125 .. 235 316 .. 196 321 .. 0.84 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.76 FIST_C 107 eleairealgddvplaGfft 126 l+ i++ l+ ++p++G+ FUN_001509-T1 100 FLRSIQKCLPLGCPFIGCTG 119 46678888877889998865 PP == domain 2 score: 23.9 bits; conditional E-value: 8.1e-09 FIST_C 48 slafagdvpeGsvvqlmlrdaedliealeraaeeaaen..e....gallfsCagRgevl.gerleeeleairealgddvplaGff 125 +l fag++++ s+v ++ +++++++++l++ ++++ ++ + l+fsC +Rg + g + e+ ++++al++ + +aGf+ FUN_001509-T1 235 GLVFAGNLQATSTV-ITGGTKQESLQNLDDSVQSLVNSdvSkensFSLMFSCFSRGSMTyGYEN-AEYLTLKDALPG-TAVAGFN 316 699***********.****************999955544134546*********887765555.4599*****876.******7 PP >> F-box-like F-box-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.3 2e-07 0.0013 7 35 .. 12 40 .. 11 48 .. 0.89 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 2e-07 F-box-like 7 EiLlqIFsyLdpkdLlrlalVCrrWrela 35 E+ I+++L+ + ++ +a+VCr W++ + FUN_001509-T1 12 EVVEIILRFLPGRCVATAAQVCRLWHDTV 40 77778*********************977 PP >> F-box F-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 5.5e-07 0.0035 7 39 .. 12 44 .. 11 48 .. 0.91 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 5.5e-07 F-box 7 ellleIlsrLdpkdllrlslVSkrwrslvkslk 39 e+++ Il++L+ + ++++++V++ w++ v + + FUN_001509-T1 12 EVVEIILRFLPGRCVATAAQVCRLWHDTVERIR 44 7999***********************998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (361 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 499 (0.0195342); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3662.13 // Query: FUN_001510-T1 [L=102] Description: FUN_001510 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 567 (0.0221961); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.40s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 1091.43 // Query: FUN_001511-T1 [L=1072] Description: FUN_001511 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-28 97.7 0.0 4.8e-13 50.0 0.0 2.6 2 Ank_2 Ankyrin repeats (3 copies) 4.1e-26 90.1 0.0 9.1e-08 32.5 0.0 5.5 5 Ank Ankyrin repeat 4.3e-23 81.6 0.1 3.5e-08 34.1 0.0 4.5 4 Ank_5 Ankyrin repeats (many copies) 1.1e-20 73.7 0.0 8.5e-08 32.8 0.0 5.1 5 Ank_4 Ankyrin repeats (many copies) 1.3e-17 64.3 15.8 1.5e-17 64.1 15.2 1.4 1 Ion_trans Ion transport protein 4e-17 60.9 0.0 6.6e-06 26.5 0.0 6.0 5 Ank_3 Ankyrin repeat 4e-13 49.8 9.9 1.9e-11 44.3 1.5 2.6 2 PKD_channel Polycystin cation channel 0.00034 21.5 7.1 0.14 13.1 0.2 3.3 2 Snapin_Pallidin Snapin/Pallidin ------ inclusion threshold ------ 0.13 12.8 1.0 6.7 7.2 0.1 2.7 2 Baculo_PEP_C Baculovirus polyhedron envelope protein, PEP 0.16 12.1 4.5 0.45 10.7 0.5 3.4 3 Trimer_CC Trimerisation motif 0.4 11.5 5.7 0.82 10.5 5.7 1.5 1 DUF6050 Family of unknown function (DUF6050) 1.3 9.8 3.8 5 7.9 0.2 3.5 2 XhlA Haemolysin XhlA 2.5 7.2 5.4 0.94 8.6 0.8 2.4 3 Tweety Tweety 3.3 8.3 10.7 1.4 9.5 1.2 2.8 3 DUF1664 Protein of unknown function (DUF1664) 5.3 7.8 8.0 4.8 7.9 0.2 3.8 4 DUF948 Bacterial protein of unknown function (DUF94 6.1 7.2 5.8 3.7 8.0 0.1 3.1 4 HSBP1 Heat shock factor binding protein 1 Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.0 0.0 3e-16 4.8e-13 11 89 .. 194 275 .. 186 276 .. 0.91 2 ! 46.0 0.1 5.2e-15 8.3e-12 27 90 .] 277 343 .. 271 343 .. 0.87 Alignments for each domain: == domain 1 score: 50.0 bits; conditional E-value: 3e-16 Ank_2 11 elvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 e ++ Ll +ga++n d +g++ Lh ++ +e++++++e++advn d++grt+Lh+Aa+ ++ e+v++L+e+gad++++ FUN_001511-T1 194 EHIQSLLrKGASVNTSDRFGQSLLHEVSRTWGIEVAQFFIEQSADVNkaDDYGRTPLHVAASADYPEMVRFLIENGADFHVT 275 56899999******9999*******88887668********999999999****************************9875 PP == domain 2 score: 46.0 bits; conditional E-value: 5.2e-15 Ank_2 27 k.ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 k + +t+Lh+Aa+n ++vk+Ll++ga ++ d ++rt+L++Aae ++ e++++L+e ga+ a+d FUN_001511-T1 277 KgELQTPLHFAARNEASQCVKILLAYGATLEvrDYKQRTPLQLAAETNSAECARILMEAGASAGARD 343 44459*********************97766779***********************9999987766 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.42 6.8e+02 18 32 .. 196 210 .. 190 211 .. 0.81 2 ! 8.7 0.0 0.0021 3.4 2 32 .. 213 243 .. 212 244 .. 0.91 3 ! 32.5 0.0 5.7e-11 9.1e-08 1 32 [. 245 276 .. 245 277 .. 0.92 4 ! 22.2 0.0 1.1e-07 0.00017 3 32 .. 281 310 .. 279 311 .. 0.91 5 ! 18.0 0.0 2.4e-06 0.0038 3 32 .. 314 343 .. 312 344 .. 0.92 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.42 Ank 18 vklLLkhGAdvnard 32 ++ LL++GA+vn d FUN_001511-T1 196 IQSLLRKGASVNTSD 210 6779978*****887 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0021 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G++ LH +r +ev+++ +++ Advn d FUN_001511-T1 213 GQSLLHEVSRTWGIEVAQFFIEQSADVNKAD 243 8999**9899999********889****988 PP == domain 3 score: 32.5 bits; conditional E-value: 5.7e-11 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G+TPLH+Aa+a+++e+v++L+++GAd ++++ FUN_001511-T1 245 YGRTPLHVAASADYPEMVRFLIENGADFHVTT 276 69********************98***99887 PP == domain 4 score: 22.2 bits; conditional E-value: 1.1e-07 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH Aar+ ++vk+LL +GA + +rd FUN_001511-T1 281 QTPLHFAARNEASQCVKILLAYGATLEVRD 310 7*******9999********77**999998 PP == domain 5 score: 18.0 bits; conditional E-value: 2.4e-06 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPL lAa+ ++ e++++L ++GA+ ard FUN_001511-T1 314 RTPLQLAAETNSAECARILMEAGASAGARD 343 8*******************98**999988 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.12 2e+02 1 28 [. 199 225 .. 199 237 .. 0.75 2 ! 34.1 0.0 2.2e-11 3.5e-08 6 47 .. 236 277 .. 233 280 .. 0.92 3 ! 20.5 0.0 4.1e-07 0.00065 12 46 .. 276 310 .. 273 310 .. 0.87 4 ! 20.5 0.0 4.1e-07 0.00065 12 53 .. 309 350 .. 305 352 .. 0.89 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.12 Ank_5 1 LlengpadlnrldgegytpLhvAakyga 28 Ll g a++n++d++g+ Lh +++ FUN_001511-T1 199 LLRKG-ASVNTSDRFGQSLLHEVSRTWG 225 67777.999*******999996666555 PP == domain 2 score: 34.1 bits; conditional E-value: 2.2e-11 Ank_5 6 padlnrldgegytpLhvAakygaleivrlLlangvdlnlkde 47 +ad+n d++g tpLhvAa+++++e+vr+L++ng+d +++++ FUN_001511-T1 236 SADVNKADDYGRTPLHVAASADYPEMVRFLIENGADFHVTTK 277 69**********************************888875 PP == domain 3 score: 20.5 bits; conditional E-value: 4.1e-07 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkd 46 + ge +tpLh+Aa++ a+++v++Lla+g+ l ++d FUN_001511-T1 276 TKGELQTPLHFAARNEASQCVKILLAYGATLEVRD 310 567899*********************99777765 PP == domain 4 score: 20.5 bits; conditional E-value: 4.1e-07 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 +d + tpL +Aa+++++e++r+L++ g++++++de+g ++l FUN_001511-T1 309 RDYKQRTPLQLAAETNSAECARILMEAGASAGARDESGMSAL 350 566677********************************8777 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.003 4.8 13 38 .. 196 221 .. 177 223 .. 0.87 2 ! 30.4 0.0 2.9e-10 4.7e-07 10 50 .] 226 266 .. 225 266 .. 0.97 3 ! 32.8 0.0 5.3e-11 8.5e-08 4 50 .] 253 300 .. 252 300 .. 0.95 4 ! 11.6 0.0 0.00025 0.39 11 49 .. 294 332 .. 292 333 .. 0.94 5 ! 8.1 0.0 0.0031 4.9 3 35 .. 319 351 .. 317 352 .. 0.91 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.003 Ank_4 13 lklLlengadinatdgngetaLhfAa 38 +++Ll +ga++n++d++g++ Lh ++ FUN_001511-T1 196 IQSLLRKGASVNTSDRFGQSLLHEVS 221 7999*******************876 PP == domain 2 score: 30.4 bits; conditional E-value: 2.9e-10 Ank_4 10 lellklLlengadinatdgngetaLhfAasngnlevlklLl 50 +e++++ +e ad+n+ d++g+t+Lh Aas ++e++++L+ FUN_001511-T1 226 IEVAQFFIEQSADVNKADDYGRTPLHVAASADYPEMVRFLI 266 5899************************************8 PP == domain 3 score: 32.8 bits; conditional E-value: 5.3e-11 Ank_4 4 AaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 Aa++ e++++L+engad++ t g+ +t+LhfAa+n+ +++k Ll FUN_001511-T1 253 AASADYPEMVRFLIENGADFHVTtKGELQTPLHFAARNEASQCVKILL 300 8999999****************999999****************997 PP == domain 4 score: 11.6 bits; conditional E-value: 0.00025 Ank_4 11 ellklLlengadinatdgngetaLhfAasngnlevlklL 49 +++k Ll++ga + +d+ ++t+L+ Aa ++ e+++ L FUN_001511-T1 294 QCVKILLAYGATLEVRDYKQRTPLQLAAETNSAECARIL 332 589*******************************99876 PP == domain 5 score: 8.1 bits; conditional E-value: 0.0031 Ank_4 3 aAaksghlellklLlengadinatdgngetaLh 35 Aa+ + e+++ L e ga+ a+d++g++aL+ FUN_001511-T1 319 LAAETNSAECARILMEAGASAGARDESGMSALT 351 58889999***********************96 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.1 15.2 9.3e-21 1.5e-17 33 242 .. 470 721 .. 434 722 .. 0.79 Alignments for each domain: == domain 1 score: 64.1 bits; conditional E-value: 9.3e-21 Ion_trans 33 klleildlvftviftlemllkiialgl.............................................kkkYlrspwnilDfvvvlpslisl 83 +++ i+ +++v+ tl + k + + k+ Y+++ wn +D++ +l++++ + FUN_001511-T1 470 NFWRIFVDALVVFLTLNEIRKEVKEFYqsrrenkkfiswrkkevkrdkqyshprwtqertfikqhvreikerKRFYFQDRWNYFDWLTYLMLIVVI 565 677777666667777766666666555667777777777777777777777777777777777777888988888********************* PP Ion_trans 84 il.......ses...k.eslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekewenpdn 168 il + + + +++l+ ++ ++rll+++r +++ +v +l ++l++ ++ +++++++ + +a+++ lf +n+++ FUN_001511-T1 566 ILhiinvvvQ-NdryNgVFIRILACSIIFVWIRLLKFARPFPTQGPFVVILDNILGDTFRWAFVIAMFYIPYAVAFWMLF----------GGNAEH 650 **99876541.2443257777888888899**************************************************..........788889 PP Ion_trans 169 grtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqeltera 242 + +dn+++ ++++++ +++g ++l+e+ ++++ ++ ++f+il++++l+nl+ia+++++fq+++++a FUN_001511-T1 651 PVKGYDNVLHLMYTVIRYPLVDNYGF---EGLEERAPVMSRVLSGSFLILSAIVLMNLYIALLSNTFQRVYDNA 721 9999*************999998886...6667777889999***************************99875 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 4.9 7.8e+03 16 30 .. 194 207 .. 189 208 .. 0.85 2 ? 3.2 0.0 0.18 2.9e+02 2 30 .. 213 240 .. 212 241 .. 0.91 3 ! 26.5 0.0 4.1e-09 6.6e-06 1 30 [. 245 273 .. 245 274 .. 0.96 4 ! 16.2 0.0 9.8e-06 0.016 3 29 .. 281 306 .. 279 308 .. 0.92 5 ? 6.7 0.0 0.013 20 2 28 .. 313 338 .. 312 341 .. 0.89 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 4.9 Ank_3 16 eivklLleklgadin 30 e ++ Ll+ +ga++n FUN_001511-T1 194 EHIQSLLR-KGASVN 207 56999***.***999 PP == domain 2 score: 3.2 bits; conditional E-value: 0.18 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 g+++Lh + r +e++++++e + ad+n FUN_001511-T1 213 GQSLLHEVSRTWGIEVAQFFIE-QSADVN 240 899999999999999*******.9***99 PP == domain 3 score: 26.5 bits; conditional E-value: 4.1e-09 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+tpLh+Aa+ + +e+v++L+e +gad++ FUN_001511-T1 245 YGRTPLHVAASADYPEMVRFLIE-NGADFH 273 79*********************.****97 PP == domain 4 score: 16.2 bits; conditional E-value: 9.8e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 +tpLh+Aarn + vk Ll +ga + FUN_001511-T1 281 QTPLHFAARNEASQCVKILLA-YGATL 306 8********************.**987 PP == domain 5 score: 6.7 bits; conditional E-value: 0.013 Ank_3 2 gntpLhlAarngrleivklLleklgad 28 +tpL lAa+ ++ e ++ L e ga+ FUN_001511-T1 313 QRTPLQLAAETNSAECARILME-AGAS 338 58*************9999999.8876 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 1.8 0.00049 0.79 24 67 .. 530 573 .. 528 583 .. 0.88 2 ! 44.3 1.5 1.2e-14 1.9e-11 95 225 .] 582 717 .. 575 717 .. 0.93 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00049 PKD_channel 24 fvveeilkirkerasylrsvwnlldlaivvlsvvlivlailrev 67 f+++ + +i++ ++ y+++ wn d + +++ +v+i+l+i+ v FUN_001511-T1 530 FIKQHVREIKERKRFYFQDRWNYFDWLTYLMLIVVIILHIINVV 573 7888889999999**************************98765 PP == domain 2 score: 44.3 bits; conditional E-value: 1.2e-14 PKD_channel 95 llriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtqasn....fsnlvksiltlfrl.ilgdfqyt 185 ++ ila+ +++++++llk+ r ++t + l + l d + a+vi+++ + ya++ +lfG +a+ + n + + t++r+ ++++ +++ FUN_001511-T1 582 VFIRILACSIIFVWIRLLKFARPFPTQGPFVVILDNILGDTFRWAFVIAMFYIPYAVAFWMLFGGNAEHpvkgYDNVLHLMYTVIRYpLVDNYGFE 677 566799**********************************************************997544444*************978899**** PP PKD_channel 186 elesgnrvLGpllllalvflvifillnlflaiindsyeev 225 le+ v++ +l ++ +l++++l+nl +a++ ++++ v FUN_001511-T1 678 GLEERAPVMSRVLSGSFLILSAIVLMNLYIALLSNTFQRV 717 ***********************************99865 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.2 8.5e-05 0.14 12 60 .. 802 853 .. 795 865 .. 0.81 2 ! 11.0 0.2 0.0004 0.63 10 62 .. 907 962 .. 901 970 .. 0.81 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 8.5e-05 Snapin_Pallidin 12 epklkeldeklkelrqsQeeLleqidrlaeeLqeleelqe...evlpdlkey 60 +++ + + e + l++sQ+e+++++d+l+ +L+e+ l+ e +++++++ FUN_001511-T1 802 KSEFDTVLEDIGHLKRSQKEMQKSLDSLHLRLEEIGSLNAviyEEVTKVMQH 853 6677888899999**********************99998555555555554 PP == domain 2 score: 11.0 bits; conditional E-value: 0.0004 Snapin_Pallidin 10 llepklkeldeklkelrqsQeeLleqidrlaeeLqeleelqe...evlpdlkeyak 62 l ++l+++ ke Q++L+e+i++ ++L++l el++ + ++++++y+ FUN_001511-T1 907 NLNKRFDKLETEFKEASFRQDKLAEEITEGFSKLERLVELEQemtARIANIEAYIV 962 56677899**********************************55555666666655 PP >> Baculo_PEP_C Baculovirus polyhedron envelope protein, PEP, C terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.1 0.0042 6.7 24 85 .. 835 899 .. 799 920 .. 0.50 2 ? 4.4 0.1 0.033 52 34 97 .. 906 964 .. 899 989 .. 0.61 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0042 Baculo_PEP_C 24 airlqnvqilaqlttlldaietqLndls...edlesllaeldtrldtlltnLtdalnqlqdtlrn 85 i ++n+ i ++t+ +++ ++q+++++ +++ l ++++++++ l+++++ + ++l+++ ++ FUN_001511-T1 835 EIGSLNAVIYEEVTKVMQHGKEQMSAIDgvnDHVAMLCNNMEEKFQGLSSEVDLKFKTLETEANE 899 33444444444444444444443333321113344444444444444444444444444433333 PP == domain 2 score: 4.4 bits; conditional E-value: 0.033 Baculo_PEP_C 34 aqlttlldaietqLndlsedlesllaeldtrldtlltnLtdalnqlqdtlrneLtnlnsiltnL 97 ++l++ +d++et++++ s + +l++e+++ +++L+ l +l+++++ ++ n+++ + L FUN_001511-T1 906 GNLNKRFDKLETEFKEASFRQDKLAEEITE----GFSKLE-RLVELEQEMTARIANIEAYIVHL 964 556666666666666655555555554444....333443.34456666666666666665554 PP >> Trimer_CC Trimerisation motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 1.4 2.2e+03 27 45 .. 811 829 .. 809 838 .. 0.73 2 ? 0.1 0.0 0.56 8.9e+02 37 47 .. 907 917 .. 903 920 .. 0.86 3 ? 10.7 0.5 0.00028 0.45 3 30 .. 1031 1058 .. 1029 1060 .. 0.94 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1.4 Trimer_CC 27 elrkLqatVQelQkRlDrL 45 ++ +L+ e+Qk lD L FUN_001511-T1 811 DIGHLKRSQKEMQKSLDSL 829 566666667899*****66 PP == domain 2 score: 0.1 bits; conditional E-value: 0.56 Trimer_CC 37 elQkRlDrLEe 47 +l kR D+LE FUN_001511-T1 907 NLNKRFDKLET 917 589******95 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00028 Trimer_CC 3 ssrrratpeasgtpssdavSRLEEelrk 30 +r+r+ + +s +++ + + RL E+lrk FUN_001511-T1 1031 KQRKRTITMSSQAARDEFIARLKENLRK 1058 579************************8 PP >> DUF6050 Family of unknown function (DUF6050) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 5.7 0.00051 0.82 13 99 .. 558 639 .. 547 710 .. 0.81 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00051 DUF6050 13 ntvlplvivlilflvlksvtknGesldyfvlllvcglPfGiknmfvflvpakvstlvlnviiGcliGdvvliwklalalyyipltiy 99 + ++iv+i+ +++ v++n f+ +l c++ f ++ +f p vi+ ++Gd + w +++a++yip+++ FUN_001511-T1 558 YL---MLIVVIILHIINVVVQNDRYNGVFIRILACSIIFVWIRLLKFARPFPTQGP-FVVILDNILGDT-FRWAFVIAMFYIPYAVA 639 33...455555555666666777777889999*******99999999887544433.346889999996.79************874 PP >> XhlA Haemolysin XhlA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.2 0.0031 5 11 46 .. 803 838 .. 799 841 .. 0.87 2 ? 0.4 0.2 0.7 1.1e+03 10 42 .. 909 941 .. 906 967 .. 0.63 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0031 XhlA 11 tkldnleervdkLeekaaeadekiknlcedlkelee 46 ++ d+ e++ L++ + e+++++++l+ +l+e+ + FUN_001511-T1 803 SEFDTVLEDIGHLKRSQKEMQKSLDSLHLRLEEIGS 838 56678888999**********************976 PP == domain 2 score: 0.4 bits; conditional E-value: 0.7 XhlA 10 etkldnleervdkLeekaaeadekiknlcedlk 42 +++ d+le++ +++ ++++ e+i + +l+ FUN_001511-T1 909 NKRFDKLETEFKEASFRQDKLAEEITEGFSKLE 941 667777777644444444444444444444444 PP >> Tweety Tweety # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.8 0.00059 0.94 146 245 .. 490 595 .. 473 602 .. 0.64 2 ? -0.3 0.2 0.29 4.7e+02 107 160 .. 862 916 .. 837 961 .. 0.59 3 ? -3.0 0.0 1.9 3e+03 134 171 .. 926 963 .. 913 978 .. 0.78 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00059 Tweety 146 tkleeilakrtdylqavrklqraveeliqqlaalpkaknae....vsleelaektel.....velyRWlaylllllldlviClvlllglarkskcl 232 ++++e +++r ++ + + ++ v+ +q+ p + + + ++ e+ e+ + ++++ Wl+yl+l ++++++ ++ ++ + + FUN_001511-T1 490 KEVKEFYQSRRENKKFISWRKKEVKRDKQYS--HPRWTQERtfikQHVREIKERKRFyfqdrWNYFDWLTYLML-IVVIILHIINVVVQNDRYNGV 582 5677777888888888877777777766665..35555444344445555666555411111677778888754.445566666666666677788 PP Tweety 233 livllvlgllalv 245 i +l+++++ + FUN_001511-T1 583 FIRILACSIIFVW 595 8888888887665 PP == domain 2 score: -0.3 bits; conditional E-value: 0.29 Tweety 107 dGvlqlty.slrnanhtlsgikklvsetkesleeklkeeLtkleeilakrtdylq 160 dGv+ + +n ++ ++g+++ v + ++le++ +e + le l+kr d l+ FUN_001511-T1 862 DGVNDHVAmLCNNMEEKFQGLSSEVDLKFKTLETEANERGSALEGNLNKRFDKLE 916 4554333203345555666666666666666666666665666655555555543 PP == domain 3 score: -3.0 bits; conditional E-value: 1.9 Tweety 134 kesleeklkeeLtkleeilakrtdylqavrklqravee 171 +++l e+++e +kle++++ ++++++ + +++ + + FUN_001511-T1 926 QDKLAEEITEGFSKLERLVELEQEMTARIANIEAYIVH 963 57888999999999999999999998888877665554 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.1 9.3 1.5e+04 44 74 .. 486 516 .. 484 540 .. 0.68 2 ? 9.5 1.2 0.00086 1.4 56 118 .. 814 876 .. 799 886 .. 0.78 3 ? 4.9 0.3 0.023 36 63 122 .. 907 966 .. 880 968 .. 0.83 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 9.3 DUF1664 44 esvskqleqvseslaatKkeLsqridrvdkk 74 +++ k+++++++s ++ Kk +s r ++v++ FUN_001511-T1 486 NEIRKEVKEFYQSRRENKKFISWRKKEVKRD 516 6677788888888888888777777766554 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00086 DUF1664 56 slaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklk 118 +l++ +ke+++ +d++ +l+e + + i eevt+v ++ ++ + ++ v++ v l ++++ FUN_001511-T1 814 HLKRSQKEMQKSLDSLHLRLEEIGSLNAVIYEEVTKVMQHGKEQMSAIDGVNDHVAMLCNNME 876 4677889******************************87777766677776666666555544 PP == domain 3 score: 4.9 bits; conditional E-value: 0.023 DUF1664 63 eLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklkeiee 122 +L++r d+++++ +e + + ++ ee+te ++++++ e +++ +++ ++e+ + ++ee FUN_001511-T1 907 NLNKRFDKLETEFKEASFRQDKLAEEITEGFSKLERLVELEQEMTARIANIEAYIVHLEE 966 688899999999999999999999999999999999999999999999999988888876 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 4.7 7.5e+03 16 34 .. 480 498 .. 478 513 .. 0.76 2 ? -1.4 0.1 2.4 3.8e+03 9 35 .. 699 725 .. 689 737 .. 0.64 3 ? 7.9 0.2 0.003 4.8 24 85 .. 815 876 .. 812 878 .. 0.71 4 ? 2.0 0.2 0.22 3.5e+02 38 87 .. 908 957 .. 891 959 .. 0.84 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 4.7 DUF948 16 flivtllklkktldevnkt 34 +++ tl++++k ++e+ ++ FUN_001511-T1 480 VVFLTLNEIRKEVKEFYQS 498 5567899999999988776 PP == domain 2 score: -1.4 bits; conditional E-value: 2.4 DUF948 9 AfvvLviflivtllklkktldevnktl 35 A+v++ ++++ + + ++++d++++t FUN_001511-T1 699 AIVLMNLYIALLSNTFQRVYDNARATA 725 444444555555555588888777775 PP == domain 3 score: 7.9 bits; conditional E-value: 0.003 DUF948 24 lkktldevnktleklekqldpllkettellaktnelledvneklekvdpvfeavkdlgesvs 85 lk+ +e++k+l++l+ +l+++ + + + +++ ++++ +e++ ++d v ++v++l ++++ FUN_001511-T1 815 LKRSQKEMQKSLDSLHLRLEEIGSLNAVIYEEVTKVMQHGKEQMSAIDGVNDHVAMLCNNME 876 555566666666666666666666666666666666666666*************9988875 PP == domain 4 score: 2.0 bits; conditional E-value: 0.22 DUF948 38 lekqldpllkettellaktnelledvneklekvdpvfeavkdlgesvskl 87 l+k+ d+l +e +e +++l+e+++e k+++++e ++++++++++ FUN_001511-T1 908 LNKRFDKLETEFKEASFRQDKLAEEITEGFSKLERLVELEQEMTARIANI 957 78888999999999999999999999999999999999888888877766 PP >> HSBP1 Heat shock factor binding protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 6 9.6e+03 31 39 .. 821 829 .. 820 836 .. 0.80 2 ? 8.0 0.1 0.0023 3.7 7 25 .. 868 886 .. 864 896 .. 0.83 3 ? -3.4 0.0 8 1.3e+04 32 41 .. 908 917 .. 906 920 .. 0.61 4 ? 0.6 0.1 0.46 7.3e+02 31 47 .. 949 965 .. 941 968 .. 0.78 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 6 HSBP1 31 eMssRiDdL 39 eM++ +D+L FUN_001511-T1 821 EMQKSLDSL 829 899999998 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0023 HSBP1 7 VenlLqqlqdKFqtmsdqI 25 V l +++++KFq +s+++ FUN_001511-T1 868 VAMLCNNMEEKFQGLSSEV 886 666789**********997 PP == domain 3 score: -3.4 bits; conditional E-value: 8 HSBP1 32 MssRiDdLEk 41 + +R D LE+ FUN_001511-T1 908 LNKRFDKLET 917 4566666664 PP == domain 4 score: 0.6 bits; conditional E-value: 0.46 HSBP1 31 eMssRiDdLEksiadlm 47 eM Ri ++E+ i l FUN_001511-T1 949 EMTARIANIEAYIVHLE 965 89999999998887665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1072 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2315 (0.0906244); expected 510.9 (0.02) Passed bias filter: 1004 (0.0393032); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 23 (0.000900372); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.53u 0.40s 00:00:00.93 Elapsed: 00:00:00.43 # Mc/sec: 10102.86 // Query: FUN_001512-T1 [L=240] Description: FUN_001512 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.15 12.5 0.1 0.26 11.7 0.1 1.3 1 DNA_photolyase DNA photolyase 0.49 11.2 3.5 0.19 12.5 0.7 1.7 2 YlqD YlqD protein Domain annotation for each model (and alignments): >> DNA_photolyase DNA photolyase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 2e-05 0.26 56 97 .. 88 129 .. 71 141 .. 0.87 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 2e-05 DNA_photolyase 56 adLdeelrergirLvvrrgdpadvlpelakelgasavvanre 97 +dL+e+l++rg +L ++ + +++l++l++e++ +a++++ FUN_001512-T1 88 KDLQERLSARGQELQFTVAQLRNKLKKLISECKKAALIVKTV 129 69*******************************999988765 PP >> YlqD YlqD protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.7 1.5e-05 0.19 15 54 .. 84 123 .. 80 141 .. 0.82 2 ? -2.5 0.1 0.69 8.8e+03 69 83 .. 207 221 .. 179 231 .. 0.43 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.5e-05 YlqD 15 eklKeelqaqlqaqikqlekelqqLefqlkrlikelkkqs 54 klK++lq++l+a+ ++l+ ++qL+ +lk+li+e kk FUN_001512-T1 84 SKLKKDLQERLSARGQELQFTVAQLRNKLKKLISECKKAA 123 689*********************************9854 PP == domain 2 score: -2.5 bits; conditional E-value: 0.69 YlqD 69 kserlekkkqllqql 83 ++r ++k+ + + FUN_001512-T1 207 VKNRGKRKNVSSSAV 221 223333333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (240 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1916 (0.0750049); expected 510.9 (0.02) Passed bias filter: 880 (0.034449); expected 510.9 (0.02) Passed Vit filter: 87 (0.00340575); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.35s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2394.56 // Query: FUN_001513-T1 [L=222] Description: FUN_001513 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.065 14.1 0.0 0.14 13.1 0.0 1.7 1 Ank_4 Ankyrin repeats (many copies) Domain annotation for each model (and alignments): >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 5.4e-06 0.14 13 50 .] 181 218 .. 160 218 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.4e-06 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklLl 50 +++Ll +ga++n++d++g++ Lh +++ +ev+++++ FUN_001513-T1 181 IQSLLRKGASVNTSDRFGQSLLHEVSRTWGIEVAQFFI 218 899********************999887777777775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (222 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 501 (0.0196124); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2191.54 // Query: FUN_001514-T1 [L=842] Description: FUN_001514 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-22 78.0 0.6 6.9e-08 32.9 0.0 4.0 3 Ank Ankyrin repeat 3.4e-22 79.3 0.1 2.8e-12 47.5 0.1 2.6 2 Ank_2 Ankyrin repeats (3 copies) 7.4e-21 74.5 0.1 7.5e-08 33.1 0.0 3.6 3 Ank_5 Ankyrin repeats (many copies) 1.7e-16 60.4 0.1 6.4e-08 33.2 0.0 3.9 4 Ank_4 Ankyrin repeats (many copies) 2.3e-16 58.5 0.0 4.9e-06 26.9 0.0 4.5 4 Ank_3 Ankyrin repeat 5.4e-16 59.0 17.5 5.4e-16 59.0 17.5 1.8 2 Ion_trans Ion transport protein 7.5e-12 45.6 9.0 7.9e-10 39.0 1.7 2.5 2 PKD_channel Polycystin cation channel 2.1e-05 25.3 3.9 0.055 14.4 0.5 3.0 2 Snapin_Pallidin Snapin/Pallidin ------ inclusion threshold ------ 0.5 11.2 6.0 1.2 10.0 6.0 1.6 1 DUF6050 Family of unknown function (DUF6050) 0.52 10.9 1.5 17 5.9 0.1 2.5 3 Baculo_PEP_C Baculovirus polyhedron envelope protein, PEP 1.1 9.8 10.7 1.8 9.1 0.5 2.8 3 DUF1664 Protein of unknown function (DUF1664) 1.2 9.0 4.9 0.8 9.5 0.4 2.4 2 TMEM33_Pom33 Transmembrane protein 33/Nucleoporin POM33 3.3 8.5 6.7 13 6.6 0.1 3.5 2 XhlA Haemolysin XhlA 4.7 8.0 8.0 2.6 8.8 0.1 3.8 4 DUF948 Bacterial protein of unknown function (DUF94 5 7.8 13.0 1.2 9.8 0.2 3.6 3 Fib_alpha Fibrinogen alpha/beta chain family Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.9 0.0 4.1e-11 6.9e-08 1 32 [. 15 46 .. 15 47 .. 0.92 2 ! 22.6 0.0 7.5e-08 0.00013 3 32 .. 51 80 .. 49 81 .. 0.91 3 ! 18.5 0.0 1.5e-06 0.0025 3 32 .. 84 113 .. 82 114 .. 0.92 Alignments for each domain: == domain 1 score: 32.9 bits; conditional E-value: 4.1e-11 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G+TPLH+Aa+a+++e+v++L+++GAd ++++ FUN_001514-T1 15 YGRTPLHVAASADYPEMVRFLIENGADFHVTT 46 69********************98***99887 PP == domain 2 score: 22.6 bits; conditional E-value: 7.5e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH Aar+ ++vk+LL +GA + +rd FUN_001514-T1 51 QTPLHFAARNEASQCVKILLAYGATLEVRD 80 7*******9999********77**999998 PP == domain 3 score: 18.5 bits; conditional E-value: 1.5e-06 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPL lAa+ ++ e++++L ++GA+ ard FUN_001514-T1 84 RTPLQLAAESNSAECARILMEAGASAGARD 113 8*******99**********98**999988 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.0 5.6e-10 9.5e-07 53 89 .. 7 45 .. 3 46 .. 0.88 2 ! 47.5 0.1 1.6e-15 2.8e-12 27 90 .] 47 113 .. 41 113 .. 0.87 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 5.6e-10 Ank_2 53 advn..dnngrtaLhyAaesghleivklLlekgadinak 89 advn d++grt+Lh+Aa+ ++ e+v++L+e+gad++++ FUN_001514-T1 7 ADVNkaDDYGRTPLHVAASADYPEMVRFLIENGADFHVT 45 56777789**************************99875 PP == domain 2 score: 47.5 bits; conditional E-value: 1.6e-15 Ank_2 27 k.ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinakd 90 k + +t+Lh+Aa+n ++vk+Ll++ga ++ d ++rt+L++Aaes++ e++++L+e ga+ a+d FUN_001514-T1 47 KgELQTPLHFAARNEASQCVKILLAYGATLEvrDYKQRTPLQLAAESNSAECARILMEAGASAGARD 113 44459*********************97766779***********************9999987766 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.0 4.4e-11 7.5e-08 7 46 .. 7 46 .. 5 49 .. 0.93 2 ! 25.9 0.0 8.1e-09 1.4e-05 12 56 .] 46 90 .. 43 90 .. 0.92 3 ! 18.3 0.0 1.9e-06 0.0033 12 53 .. 79 120 .. 75 122 .. 0.89 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 4.4e-11 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkd 46 ad+n d++g tpLhvAa+++++e+vr+L++ng+d ++++ FUN_001514-T1 7 ADVNKADDYGRTPLHVAASADYPEMVRFLIENGADFHVTT 46 799*******************************988877 PP == domain 2 score: 25.9 bits; conditional E-value: 8.1e-09 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + ge +tpLh+Aa++ a+++v++Lla+g+ l ++d tpl+lA FUN_001514-T1 46 TKGELQTPLHFAARNEASQCVKILLAYGATLEVRDYKQRTPLQLA 90 567899*****************************888****998 PP == domain 3 score: 18.3 bits; conditional E-value: 1.9e-06 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 +d + tpL +Aa+ +++e++r+L++ g++++++de+g ++l FUN_001514-T1 79 RDYKQRTPLQLAAESNSAECARILMEAGASAGARDESGMSAL 120 566677********************************8777 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 1.7e-08 2.9e-05 20 50 .] 6 36 .. 4 36 .. 0.98 2 ! 33.2 0.0 3.8e-11 6.4e-08 4 50 .] 23 70 .. 22 70 .. 0.95 3 ! 11.6 0.0 0.00024 0.4 11 49 .. 64 102 .. 64 103 .. 0.94 4 ! 10.5 0.0 0.00053 0.9 3 35 .. 89 121 .. 87 122 .. 0.93 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 1.7e-08 Ank_4 20 gadinatdgngetaLhfAasngnlevlklLl 50 gad+n+ d++g+t+Lh Aas ++e++++L+ FUN_001514-T1 6 GADVNKADDYGRTPLHVAASADYPEMVRFLI 36 89****************************8 PP == domain 2 score: 33.2 bits; conditional E-value: 3.8e-11 Ank_4 4 AaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 Aa++ e++++L+engad++ t g+ +t+LhfAa+n+ +++k Ll FUN_001514-T1 23 AASADYPEMVRFLIENGADFHVTtKGELQTPLHFAARNEASQCVKILL 70 8999999****************999999****************997 PP == domain 3 score: 11.6 bits; conditional E-value: 0.00024 Ank_4 11 ellklLlengadinatdgngetaLhfAasngnlevlklL 49 +++k Ll++ga + +d+ ++t+L+ Aa ++ e+++ L FUN_001514-T1 64 QCVKILLAYGATLEVRDYKQRTPLQLAAESNSAECARIL 102 589*******************************99876 PP == domain 4 score: 10.5 bits; conditional E-value: 0.00053 Ank_4 3 aAaksghlellklLlengadinatdgngetaLh 35 Aa+s+ e+++ L e ga+ a+d++g++aL+ FUN_001514-T1 89 LAAESNSAECARILMEAGASAGARDESGMSALT 121 5999***************************96 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.0 2.9e-09 4.9e-06 1 30 [. 15 43 .. 15 44 .. 0.96 2 ! 16.6 0.0 6.9e-06 0.012 3 29 .. 51 76 .. 49 78 .. 0.92 3 ! 9.5 0.0 0.0014 2.4 2 28 .. 83 108 .. 82 111 .. 0.89 4 ? -1.9 0.0 7.7 1.3e+04 4 18 .. 171 185 .. 171 195 .. 0.81 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 2.9e-09 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+tpLh+Aa+ + +e+v++L+e +gad++ FUN_001514-T1 15 YGRTPLHVAASADYPEMVRFLIE-NGADFH 43 79*********************.****97 PP == domain 2 score: 16.6 bits; conditional E-value: 6.9e-06 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 +tpLh+Aarn + vk Ll +ga + FUN_001514-T1 51 QTPLHFAARNEASQCVKILLA-YGATL 76 8********************.**987 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0014 Ank_3 2 gntpLhlAarngrleivklLleklgad 28 +tpL lAa++++ e ++ L e ga+ FUN_001514-T1 83 QRTPLQLAAESNSAECARILME-AGAS 108 58*************9*99999.8876 PP == domain 4 score: -1.9 bits; conditional E-value: 7.7 Ank_3 4 tpLhlAarngrleiv 18 +pL ++++ +++e++ FUN_001514-T1 171 SPLQTVVEMNCFELI 185 699999**9999843 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 1.7 0.73 1.2e+03 35 81 .. 179 224 .. 153 262 .. 0.60 2 ! 59.0 17.5 3.1e-19 5.4e-16 32 242 .. 235 491 .. 204 492 .. 0.80 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.73 Ion_trans 35 leildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpsli 81 +++++l++ if + +k+ +g+ +++lr + n+l v+++++ i FUN_001514-T1 179 MNCFELIMHPIFQRLIEIKWKFFGV-RAWLRIFLNVLLTVSYTLLGI 224 4556777777777777777777777.777777777765555544433 PP == domain 2 score: 59.0 bits; conditional E-value: 3.1e-19 Ion_trans 32 l....klleildlvftviftlemllkiialgl.............................................kkkYlrspwnilDfvvvlp 78 + +++ i+ +++v+ tl + k + + k+ Y+++ wn +D++ +l+ FUN_001514-T1 235 SplsqNFWRIFVDALVVFLTLNEIRKEVKEFYksrrenkkftswrkkevkrdlqyshprwtqertlvqqhvreikerKRFYFQDKWNYFDWLTYLM 330 23445677777777777777777777777666677777777777777777777777777777777777778888887888**************** PP Ion_trans 79 slislil.......ses...k.eslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekew 163 +++ +il + + + +++l+ ++ ++rll+++ +++ +v +l ++l++ ++ ++++++ + +a+++ lf FUN_001514-T1 331 LIVVIILhiinvvvQ-NdryNgVFIRILACSIIFVWIRLLKFAGPFPTQGPFVVILDNILGDTFRWGFVIAMFYIPYAVAFWMLF----------G 415 *******99876541.2443256777888888899**************************************************..........8 PP Ion_trans 164 enpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqeltera 242 +n +++ +dn+++ ++++++ +++g ++l+e+ ++++ ++ ++f+il++++l+nl+ia+++++fq+++++a FUN_001514-T1 416 VNTEHPVKGYDNVLHLMYTVIRYPLVDDYGF---DGLKERAPVMSRVLSGSFLILSAIVLMNLYIALLSNTFQRVYDNA 491 999999****************888887775...9999999999******************************99875 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 1.3 0.00025 0.43 26 67 .. 302 343 .. 299 353 .. 0.84 2 ! 39.0 1.7 4.7e-13 7.9e-10 95 225 .] 352 487 .. 344 487 .. 0.93 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00025 PKD_channel 26 veeilkirkerasylrsvwnlldlaivvlsvvlivlailrev 67 ++ + +i++ ++ y++++wn d + +++ +v+i+l+i+ v FUN_001514-T1 302 QQHVREIKERKRFYFQDKWNYFDWLTYLMLIVVIILHIINVV 343 556667777779*************************98765 PP == domain 2 score: 39.0 bits; conditional E-value: 4.7e-13 PKD_channel 95 llriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtqasn....fsnlvksiltlfrl.ilgdfqyt 185 ++ ila+ +++++++llk+ ++t + l + l d + +vi+++ + ya++ +lfG +++ + n + + t++r+ +++d ++ FUN_001514-T1 352 VFIRILACSIIFVWIRLLKFAGPFPTQGPFVVILDNILGDTFRWGFVIAMFYIPYAVAFWMLFGVNTEHpvkgYDNVLHLMYTVIRYpLVDDYGFD 447 566799**********************************************************987543444*************97899***** PP PKD_channel 186 elesgnrvLGpllllalvflvifillnlflaiindsyeev 225 l++ v++ +l ++ +l++++l+nl +a++ ++++ v FUN_001514-T1 448 GLKERAPVMSRVLSGSFLILSAIVLMNLYIALLSNTFQRV 487 ***********************************99865 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.2 0.00049 0.84 12 57 .. 572 620 .. 565 637 .. 0.78 2 ! 14.4 0.5 3.2e-05 0.055 10 62 .. 677 732 .. 671 741 .. 0.82 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00049 Snapin_Pallidin 12 epklkeldeklkelrqsQeeLleqidrlaeeLqeleelqe...evlpdl 57 +++ + + e + l++sQ+e+++++d l+ +L+e+ l+ e ++++ FUN_001514-T1 572 KSEFDTVLEDIGHLKRSQKEMQKSLDGLHLRLEEIGSLNAvtyEEVTQV 620 6677888899999**********************99988444334444 PP == domain 2 score: 14.4 bits; conditional E-value: 3.2e-05 Snapin_Pallidin 10 llepklkeldeklkelrqsQeeLleqidrlaeeLqeleelqe...evlpdlkeyak 62 l ++l+++ ke Q++L+e+i++ ++L++leel++ + ++++++y+ FUN_001514-T1 677 NLNKRFDKLETEFKEASLRQDKLAEEITEGFSKLERLEELEQemtARIANIEAYIV 732 56777899**********************************55555566666655 PP >> DUF6050 Family of unknown function (DUF6050) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 6.0 0.00069 1.2 13 99 .. 328 409 .. 317 428 .. 0.72 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00069 DUF6050 13 ntvlplvivlilflvlksvtknGesldyfvlllvcglPfGiknmfvflvpakvstlvlnviiGcliGdvvliwklalalyyipltiy 99 + ++iv+i+ +++ v++n f+ +l c++ f ++ +f p vi+ ++Gd + w +++a++yip+++ FUN_001514-T1 328 YL---MLIVVIILHIINVVVQNDRYNGVFIRILACSIIFVWIRLLKFAGPFPTQG-PFVVILDNILGDT-FRWGFVIAMFYIPYAVA 409 33...445555555566666777777889999*******9999999966644333.3447889999996.79************874 PP >> Baculo_PEP_C Baculovirus polyhedron envelope protein, PEP, C terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.14 2.4e+02 35 89 .. 591 644 .. 570 657 .. 0.33 2 ? 5.9 0.1 0.0099 17 17 90 .. 616 685 .. 589 690 .. 0.55 3 ? 5.0 0.2 0.02 34 34 94 .. 676 731 .. 671 742 .. 0.58 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.14 Baculo_PEP_C 35 qlttlldaietqLndlsedlesllaeldtrldtlltnLtdalnqlqdtlrneLtn 89 ++++ ld ++ +L+++ + l+++ e t++ + + +a+ ++d++ +n FUN_001514-T1 591 EMQKSLDGLHLRLEEIGS-LNAVTYEEVTQVMQHGREQMSAIDGVNDHVAMLCNN 644 222333333333333222.222222222222222222223333333333333232 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0099 Baculo_PEP_C 17 eLtnvLnairlqnvqilaqlttlldaietqLndlsedlesllaeldtrldtlltnLtdalnqlqdtlrneLtnl 90 e+t+v++ r q + i d+++ n+++e+++ l++ +d +++tl t+ ++ +l+ +l+++ + l FUN_001514-T1 616 EVTQVMQHGREQMSAI----DGVNDHVAMLCNNMEEKFQGLSNGVDLKFKTLETEANERGSALEGNLNKRFDKL 685 4455555554444433....333344444444555566666666666666666666666666655555555555 PP == domain 3 score: 5.0 bits; conditional E-value: 0.02 Baculo_PEP_C 34 aqlttlldaietqLndlsedlesllaeldt......rldtlltnLtdalnqlqdtlrneLtnlnsil 94 ++l++ +d++et++++ s + +l++e+++ r l +l+++++ ++ n+++ + FUN_001514-T1 676 GNLNKRFDKLETEFKEASLRQDKLAEEITEgfskleR-----------LEELEQEMTARIANIEAYI 731 5666666777777766655555555555553333333...........4555566666666666555 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.2 5.7 9.7e+03 44 78 .. 256 290 .. 254 311 .. 0.62 2 ? 9.1 0.5 0.0011 1.8 56 118 .. 584 646 .. 569 655 .. 0.73 3 ? 7.5 0.4 0.0034 5.8 61 122 .. 675 736 .. 649 738 .. 0.84 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 5.7 DUF1664 44 esvskqleqvseslaatKkeLsqridrvdkkldeq 78 +++ k+++++++s ++ Kk s r ++v++ l+ + FUN_001514-T1 256 NEIRKEVKEFYKSRRENKKFTSWRKKEVKRDLQYS 290 56777777777777777777777777777776654 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0011 DUF1664 56 slaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklk 118 +l++ +ke+++ +d + +l+e + + + eevt+v ++ ++ + ++ v++ v l ++++ FUN_001514-T1 584 HLKRSQKEMQKSLDGLHLRLEEIGSLNAVTYEEVTQVMQHGREQMSAIDGVNDHVAMLCNNME 646 4677889*****************************976655555555555555554444433 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0034 DUF1664 61 KkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklkeiee 122 +L++r d+++++ +e + + ++ ee+te +++++++e +++ +++ ++e+ + ++ee FUN_001514-T1 675 EGNLNKRFDKLETEFKEASLRQDKLAEEITEGFSKLERLEELEQEMTARIANIEAYIVHLEE 736 568999***********************************************999999986 PP >> TMEM33_Pom33 Transmembrane protein 33/Nucleoporin POM33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.5 0.28 4.8e+02 15 57 .. 198 240 .. 189 252 .. 0.79 2 ? 9.5 0.4 0.00047 0.8 7 67 .. 309 370 .. 303 387 .. 0.81 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.28 TMEM33_Pom33 15 anklelalwlarlltvlftvlyil.plflssesasaYykallan 57 + + + +wl +l vl+tv+y l ++ +++++Yy l++n FUN_001514-T1 198 WKFFGVRAWLRIFLNVLLTVSYTLlGITHP-NDIKQYYSPLSQN 240 556677899999**********99565555.7888999888777 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00047 TMEM33_Pom33 7 eslkqhvvanklelalwlarlltvlftvlyilplflssesas.aYykallanaatsalrLhq 67 ++ k + +k + + wl+ l+++++++l i+ +++++ ++ ++ ++l +++ + +rL + FUN_001514-T1 309 KERKRFYFQDKWNYFDWLTYLMLIVVIILHIINVVVQNDRYNgVFIRILACSIIFVWIRLLK 370 5567788889999*******************999997777767777777777777777755 PP >> XhlA Haemolysin XhlA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.1 0.0074 13 11 46 .. 573 608 .. 569 611 .. 0.87 2 ? 2.1 2.0 0.2 3.3e+02 10 46 .. 679 715 .. 676 738 .. 0.67 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0074 XhlA 11 tkldnleervdkLeekaaeadekiknlcedlkelee 46 ++ d+ e++ L++ + e++++++ l+ +l+e+ + FUN_001514-T1 573 SEFDTVLEDIGHLKRSQKEMQKSLDGLHLRLEEIGS 608 56678888999**********************966 PP == domain 2 score: 2.1 bits; conditional E-value: 0.2 XhlA 10 etkldnleervdkLeekaaeadekiknlcedlkelee 46 +++ d+le++ +++ +++++ e+i + +l++lee FUN_001514-T1 679 NKRFDKLETEFKEASLRQDKLAEEITEGFSKLERLEE 715 6677777777677777777777777666666665554 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 2.1 3.6e+03 15 37 .. 249 271 .. 246 288 .. 0.74 2 ? -1.0 0.1 1.7 2.9e+03 9 35 .. 469 495 .. 459 507 .. 0.64 3 ? 8.8 0.1 0.0016 2.6 24 84 .. 585 645 .. 581 647 .. 0.90 4 ? 0.7 0.2 0.49 8.4e+02 56 76 .. 696 716 .. 672 745 .. 0.46 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 2.1 DUF948 15 iflivtllklkktldevnktlek 37 ++++ tl++++k ++e+ k+ ++ FUN_001514-T1 249 LVVFLTLNEIRKEVKEFYKSRRE 271 45667999999999998887665 PP == domain 2 score: -1.0 bits; conditional E-value: 1.7 DUF948 9 AfvvLviflivtllklkktldevnktl 35 A+v++ ++++ + + ++++d++++t FUN_001514-T1 469 AIVLMNLYIALLSNTFQRVYDNARATA 495 444444555555555588888877775 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0016 DUF948 24 lkktldevnktleklekqldpllkettellaktnelledvneklekvdpvfeavkdlgesv 84 lk+ +e++k+l++l+ +l+++ + + + +++ ++++ +e++ ++d v ++v++l +++ FUN_001514-T1 585 LKRSQKEMQKSLDGLHLRLEEIGSLNAVTYEEVTQVMQHGREQMSAIDGVNDHVAMLCNNM 645 788889999999999999999999999999999999999999*************998887 PP == domain 4 score: 0.7 bits; conditional E-value: 0.49 DUF948 56 tnelledvneklekvdpvfea 76 +++l+e+++e k++++ e FUN_001514-T1 696 QDKLAEEITEGFSKLERLEEL 716 334444443333333332222 PP >> Fib_alpha Fibrinogen alpha/beta chain family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.5 0.55 9.3e+02 37 75 .. 255 293 .. 251 319 .. 0.58 2 ? 9.8 0.2 0.00069 1.2 25 104 .. 584 663 .. 582 666 .. 0.93 3 ? 7.9 0.5 0.0027 4.6 33 130 .. 634 736 .. 632 738 .. 0.82 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.55 Fib_alpha 37 iekLeneleelsnstkeakelvkaikdslrerqkskkdn 75 ++++++e++e+ +s +e k+ ++ k+ ++++ + ++++ FUN_001514-T1 255 LNEIRKEVKEFYKSRRENKKFTSWRKKEVKRDLQYSHPR 293 677777777777777777777766666666666655543 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00069 Fib_alpha 25 lllkqekevkkdiekLeneleelsnstkeakelvkaikdslrerqkskkdndnvvkkvskeleeeiaklketvdeqesni 104 l++ +ke++k+++ L+ +lee+ + + ++e v+++++ re+ + ++ ++ v + +++ee+ + l + vd +++++ FUN_001514-T1 584 HLKRSQKEMQKSLDGLHLRLEEIGSLNAVTYEEVTQVMQHGREQMSAIDGVNDHVAMLCNNMEEKFQGLSNGVDLKFKTL 663 68999********************************************99************99999999999888766 PP == domain 3 score: 7.9 bits; conditional E-value: 0.0027 Fib_alpha 33 vkkdiekLenele.elsnstkeakelvkaikdslrerqkskkdn.dnvvkkvskelee...eiaklketvdeqesnirvLqevlesnrqkiqkLeq 123 v+++++ L n++e +++ ++ ++ k++++ +er + ++n ++ + k+++e +e ++ kl e+++e +s+++ L e+ ++ +i+++e FUN_001514-T1 634 VNDHVAMLCNNMEeKFQGLSNGVDLKFKTLETEANERGSALEGNlNKRFDKLETEFKEaslRQDKLAEEITEGFSKLERLEELEQEMTARIANIEA 729 56667777777752567788899999999999999999999999888888888777653336778999**************************** PP Fib_alpha 124 didqkee 130 i +ee FUN_001514-T1 730 YIVHLEE 736 *999886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (842 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2424 (0.0948914); expected 510.9 (0.02) Passed bias filter: 1022 (0.0400078); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.49u 0.37s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 8020.51 // Query: FUN_001515-T1 [L=828] Description: FUN_001515 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-24 84.4 0.2 7.6e-07 29.6 0.0 5.8 5 Ank Ankyrin repeat 7.3e-24 84.7 0.1 1.2e-14 55.1 0.0 2.7 2 Ank_2 Ankyrin repeats (3 copies) 7.4e-18 64.9 0.0 5.2e-09 36.8 0.0 3.6 3 Ank_5 Ankyrin repeats (many copies) 2e-17 63.6 18.6 4.1e-17 62.7 18.0 1.7 2 Ion_trans Ion transport protein 1.9e-16 60.6 11.6 2.3e-13 50.6 9.1 2.4 2 PKD_channel Polycystin cation channel 1.2e-15 56.3 0.0 0.00011 22.8 0.0 5.7 5 Ank_3 Ankyrin repeat 5.1e-14 52.5 0.1 1.4e-05 25.8 0.0 4.7 5 Ank_4 Ankyrin repeats (many copies) ------ inclusion threshold ------ 0.012 16.7 4.0 0.021 15.9 1.5 2.4 2 MerC MerC mercury resistance protein 0.03 14.7 3.7 0.085 13.2 3.7 1.8 1 LXG LXG domain of WXG superfamily 0.036 15.0 1.7 7.5 7.5 0.1 2.6 2 DUF6232 Family of unknown function (DUF6232) 0.051 13.9 0.0 0.26 11.7 0.0 2.2 2 ANK_LRRK2 LRRK2 ANK repeat 0.21 12.5 0.7 33 5.5 0.1 2.6 2 DASH_Hsk3 DASH complex subunit Hsk3 like 1.2 10.0 8.3 0.99 10.3 5.8 2.2 2 Tup_N Tup N-terminal 1.6 9.4 8.6 2.6 8.8 4.5 2.4 2 End3 Actin cytoskeleton-regulatory complex protein EN 7.4 7.8 8.9 1.2 10.4 3.5 2.2 2 Hep_59 Hepatocellular carcinoma-associated antigen 59 Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.091 1.5e+02 15 32 .. 166 183 .. 154 184 .. 0.81 2 ! 24.7 0.0 1.6e-08 2.7e-05 1 33 [] 185 217 .. 185 217 .. 0.95 3 ! 29.6 0.0 4.5e-10 7.6e-07 1 32 [. 218 249 .. 218 250 .. 0.94 4 ! 12.0 0.0 0.00018 0.3 3 32 .. 254 283 .. 253 284 .. 0.87 5 ! 7.1 0.0 0.0064 11 3 24 .. 287 308 .. 285 317 .. 0.84 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.091 Ank 15 levvklLLkhGAdvnard 32 le v+ L+++GA vn d FUN_001515-T1 166 LEFVQTLIDNGAAVNTAD 183 899*****88**9*9877 PP == domain 2 score: 24.7 bits; conditional E-value: 1.6e-08 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnardk 33 +G+T LH Aar +l+v+klLL++GA vn+ dk FUN_001515-T1 185 HGQTLLHEAARQWDLSVAKLLLERGAVVNQPDK 217 79********99**********88*****9996 PP == domain 3 score: 29.6 bits; conditional E-value: 4.5e-10 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnard 32 +G+TPLH+Aa +++e+v++L+++G d++a++ FUN_001515-T1 218 YGRTPLHVAAAVDYPEMVQFLVQRGGDIHAKT 249 69********9***********889****986 PP == domain 4 score: 12.0 bits; conditional E-value: 0.00018 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TP H Aar++ + +L+k GAd+ +d FUN_001515-T1 254 QTPVHFAARNDASLSLMMLIKCGADITDKD 283 6*******97878888899988****9887 PP == domain 5 score: 7.1 bits; conditional E-value: 0.0064 Ank 3 nTPLHlAaraghlevvklLLkh 24 +T+L +Aa+ ++ e+++ L+++ FUN_001515-T1 287 RTALQVAAELDRSETARCLIER 308 8*******99**********54 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.1 0.0 7e-18 1.2e-14 9 89 .. 165 248 .. 154 249 .. 0.92 2 ! 26.8 0.0 4.8e-09 8.2e-06 2 66 .. 258 325 .. 252 342 .. 0.76 Alignments for each domain: == domain 1 score: 55.1 bits; conditional E-value: 7e-18 Ank_2 9 nlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 +le+v+ L+ +ga +n d g+t Lh Aa++ l ++klLle ga vn d++grt+Lh+Aa ++ e+v++L+++g di+ak FUN_001515-T1 165 DLEFVQTLIdNGAAVNTADRHGQTLLHEAARQWDLSVAKLLLERGAVVNqpDKYGRTPLHVAAAVDYPEMVQFLVQRGGDIHAK 248 5799************9999*************99********997788899***********99**********999999876 PP == domain 2 score: 26.8 bits; conditional E-value: 4.8e-09 Ank_2 2 mlAakngnlelvklLl.egadanlqdk..ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhy 66 ++Aa+n+ + + L+ +gad+ dk + +taL++Aa+ ++ e++++L+e + a + d+ g+taL + FUN_001515-T1 258 HFAARNDASLSLMMLIkCGADIT--DKdfKQRTALQVAAELDRSETARCLIERSsA-AGvvDDRGMTALVL 325 89999975556666665777766..5555999****99999999999****97532.22446999999976 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.9 0.0 8.9e-10 1.5e-06 1 53 [. 172 223 .. 172 223 .. 0.98 2 ! 36.8 0.0 3e-12 5.2e-09 1 56 [] 205 260 .. 205 260 .. 0.96 3 ! 9.7 0.0 0.00097 1.7 1 53 [. 272 323 .. 272 325 .. 0.96 Alignments for each domain: == domain 1 score: 28.9 bits; conditional E-value: 8.9e-10 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 L++ng a++n+ d++g+t Lh Aa++ l +++lLl++g+ +n d++g tpl FUN_001515-T1 172 LIDNG-AAVNTADRHGQTLLHEAARQWDLSVAKLLLERGAVVNQPDKYGRTPL 223 899**.**********************************************8 PP == domain 2 score: 36.8 bits; conditional E-value: 3e-12 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeeg.ltpldlA 56 Lle+g a +n +d++g tpLhvAa +++e+v++L+ +g+d+++k+ +tp+++A FUN_001515-T1 205 LLERG-AVVNQPDKYGRTPLHVAAAVDYPEMVQFLVQRGGDIHAKTVKEmQTPVHFA 260 78999.88999999999*************************************998 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00097 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 L+++g ad+ ++d + t+L vAa+ +++e +r L+++ +++++ d++g t+l FUN_001515-T1 272 LIKCG-ADITDKDFKQRTALQVAAELDRSETARCLIERSSAAGVVDDRGMTAL 323 89999.*******************************************8887 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 1.6 0.49 8.3e+02 59 102 .. 395 459 .. 375 468 .. 0.63 2 ! 62.7 18.0 2.4e-20 4.1e-17 6 241 .. 416 690 .. 409 692 .. 0.83 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.49 Ion_trans 59 l...kkkYlrspwnilDfvvvlpslislil............ses....k...eslsllrvlrllr 102 l k+kY+ + ++ ++ l+++ +++ + k l+++++l ++ FUN_001515-T1 395 LiavKWKYFGKRGAWIQVITNLFFVTLWTVlgvtspskasdfF-DpiekKwwrVVLGVIAILMTFN 459 1444679999999999999999999988887776555443331.0333212224444444444444 PP == domain 2 score: 62.7 bits; conditional E-value: 2.4e-20 Ion_trans 6 lfilllillntvvlaletyfqpeekelklleildlvftviftlemllkiialgl.......................................... 59 lf++ l + v+ + + ++ + e+k++ ++ v+ +++t+ ++ + ++ ++ FUN_001515-T1 416 LFFVTLWTVLGVTSPSKASDFFDPIEKKWWRVVLGVIAILMTFNLIRQEFMEYFaskrehrlwvkwredelrndlefchprwpgermylmqeidsl 511 445555555555555555555555555888888888888888888888888888888888888888888889999999999999999999999998 PP Ion_trans 60 ...kkkYlrspwnilDfvvvlpslislil.......ses....keslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvl 141 + +Yl++ wn++D++++ + ++sl++ + + +++l++ ++ ++rl++++r + l +v +l+++++++l++ +l++++ FUN_001515-T1 512 rhqEPSYLKDAWNFIDWLAYALIIASLAAlctaylrD-DhmalSVYINILSATLVVLWIRLMKYARAFTALGPFVVMLGHVINDVLKFGFLFFIFY 606 888889*********************9988776651.144333779999999999**************************************** PP Ion_trans 142 fifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqe 237 + +a + +f +++g ++++ + l+++f+++ + + +++ ++k + +a ++ +++i +gv+ lnl+ia+++d+fq+ FUN_001515-T1 607 IPYAASFWMVF-------------NQQGVKGYSDITDLLFSMFRMTIVD--EYNYDDLSQSK-PIMAKVLCGTYIAASGVVCLNLFIALMSDTFQR 686 ***********.............467788899***********77777..44456666666.9******************************** PP Ion_trans 238 lter 241 ++++ FUN_001515-T1 687 VYDN 690 9976 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.0 0.00027 0.46 23 59 .. 502 538 .. 501 552 .. 0.80 2 ! 50.6 9.1 1.4e-16 2.3e-13 95 225 .] 555 687 .. 544 687 .. 0.90 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00027 PKD_channel 23 yfvveeilkirkerasylrsvwnlldlaivvlsvvli 59 ++ ++ei +r++ +syl+++wn +d + ++l ++++ FUN_001515-T1 502 MYLMQEIDSLRHQEPSYLKDAWNFIDWLAYALIIASL 538 59999********************987766666543 PP == domain 2 score: 50.6 bits; conditional E-value: 1.4e-16 PKD_channel 95 llriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtq.asnfsnlvksiltlfrl.ilgdfqytele 188 ++ +il +++++++l+k+ r + + + l ++d++ f ++++i+ + ya+ ++f +q ++ +s+++ + +fr+ i+++ +y +l FUN_001515-T1 555 VYINILSATLVVLWIRLMKYARAFTALGPFVVMLGHVINDVLKFGFLFFIFYIPYAASFWMVFNQQgVKGYSDITDLLFSMFRMtIVDEYNYDDLS 650 6677778888899******************************************998877776653889************97367778999*** PP PKD_channel 189 sgnrvLGpllllalvflvifillnlflaiindsyeev 225 + ++ +l+ ++++ + ++ lnlf+a++ d+++ v FUN_001515-T1 651 QSKPIMAKVLCGTYIAASGVVCLNLFIALMSDTFQRV 687 *********************************9875 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 2.1 3.5e+03 15 30 .. 166 180 .. 163 181 .. 0.85 2 ! 12.4 0.0 0.00016 0.27 1 30 [. 185 213 .. 185 214 .. 0.93 3 ! 22.8 0.0 6.6e-08 0.00011 1 30 [. 218 246 .. 218 247 .. 0.95 4 ! 7.4 0.0 0.007 12 3 29 .. 254 279 .. 252 281 .. 0.90 5 ? 5.7 0.0 0.025 43 2 25 .. 286 308 .. 285 313 .. 0.89 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 2.1 Ank_3 15 leivklLleklgadin 30 le v+ L++ +ga +n FUN_001515-T1 166 LEFVQTLID-NGAAVN 180 56799****.***998 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00016 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+t+Lh Aar +l ++klLle +ga +n FUN_001515-T1 185 HGQTLLHEAARQWDLSVAKLLLE-RGAVVN 213 79*********************.999776 PP == domain 3 score: 22.8 bits; conditional E-value: 6.6e-08 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+tpLh+Aa + +e+v++L++ +g di+ FUN_001515-T1 218 YGRTPLHVAAAVDYPEMVQFLVQ-RGGDIH 246 79*********************.****98 PP == domain 4 score: 7.4 bits; conditional E-value: 0.007 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 +tp h+Aarn+ + +L++ +gadi FUN_001515-T1 254 QTPVHFAARNDASLSLMMLIK-CGADI 279 8************87999999.***98 PP == domain 5 score: 5.7 bits; conditional E-value: 0.025 Ank_3 2 gntpLhlAarngrleivklLlekl 25 +t+L +Aa+ +r e +++L+e + FUN_001515-T1 286 QRTALQVAAELDRSETARCLIE-R 308 58*******************9.3 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.1 2.1e-07 0.00036 10 50 .] 166 206 .. 164 206 .. 0.96 2 ! 25.8 0.0 7.9e-09 1.4e-05 10 50 .] 199 239 .. 197 239 .. 0.96 3 ! 10.4 0.0 0.00055 0.94 11 40 .. 233 263 .. 230 270 .. 0.92 4 ? 3.3 0.0 0.096 1.6e+02 4 48 .. 260 304 .. 257 306 .. 0.69 5 ? -0.0 0.0 1.1 1.8e+03 2 34 .. 291 323 .. 290 323 .. 0.82 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 2.1e-07 Ank_4 10 lellklLlengadinatdgngetaLhfAasngnlevlklLl 50 le +++L++nga +n+ d+ g+t Lh Aa+ +l+v+klLl FUN_001515-T1 166 LEFVQTLIDNGAAVNTADRHGQTLLHEAARQWDLSVAKLLL 206 889************************************97 PP == domain 2 score: 25.8 bits; conditional E-value: 7.9e-09 Ank_4 10 lellklLlengadinatdgngetaLhfAasngnlevlklLl 50 l ++klLle ga +n d++g+t+Lh Aa+ ++e++++L+ FUN_001515-T1 199 LSVAKLLLERGAVVNQPDKYGRTPLHVAAAVDYPEMVQFLV 239 7899***********************************96 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00055 Ank_4 11 ellklLlengadinat.dgngetaLhfAasn 40 e++++L++ g di+a ++ +t++hfAa+n FUN_001515-T1 233 EMVQFLVQRGGDIHAKtVKEMQTPVHFAARN 263 89**************99***********98 PP == domain 4 score: 3.3 bits; conditional E-value: 0.096 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 Aa l +L++ gadi + d ++taL+ Aa + e +++ FUN_001515-T1 260 AARNDASLSLMMLIKCGADITDKDFKQRTALQVAAELDRSETARC 304 5554444457778877*******878********96555555555 PP == domain 5 score: -0.0 bits; conditional E-value: 1.1 Ank_4 2 haAaksghlellklLlengadinatdgngetaL 34 +Aa+ + e+++ L+e +d+ g+taL FUN_001515-T1 291 QVAAELDRSETARCLIERSSAAGVVDDRGMTAL 323 5788888889999999987767778999***98 PP >> MerC MerC mercury resistance protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 1.1 1.9e+03 62 78 .. 442 458 .. 380 471 .. 0.73 2 ? 15.9 1.5 1.2e-05 0.021 37 106 .. 524 593 .. 511 594 .. 0.87 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 1.1 MerC 62 rkllplvlgllGlalll 78 +k++++vlg++++++ + FUN_001515-T1 442 KKWWRVVLGVIAILMTF 458 45666666666665544 PP == domain 2 score: 15.9 bits; conditional E-value: 1.2e-05 MerC 37 lfhrlllilvlliallalllgy.rrhrkllplvlgllGlallllalllggaieklltvlGslllivahvln 106 f +l+++ ++ +l+al +y r + +l +++ +l+ +l++l + l+ ++ +++t lG ++++++hv+n FUN_001515-T1 524 NFIDWLAYALIIASLAALCTAYlRDDHMALSVYINILSATLVVLWIRLM-KYARAFTALGPFVVMLGHVIN 593 4899******************777788888888899999998888888.89999**************99 PP >> LXG LXG domain of WXG superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 3.7 5e-05 0.085 116 198 .. 743 825 .. 732 828 .] 0.92 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 5e-05 LXG 116 eeltdeinsilasvsdivslpklsdsevkeklqkakkkvqetieklyelDqeqtseleeleediqalkayvseleemtsngki 198 +el++ + +i ++v++i + + s+ k k + + ++v + e+l++l+q+q + ++ ++i+++k+ + ++ +++ ++k+ FUN_001515-T1 743 KELQRMTHQIKEQVDHIYTHINEQESDRKRKSNGSSNDVHKLREDLKKLEQQQRVFSSQFHSQISEVKDMLGDVLHTLGKRKK 825 577888889999*****99999999999**********************************************999998876 PP >> DUF6232 Family of unknown function (DUF6232) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.1 0.0044 7.5 56 93 .. 444 484 .. 394 487 .. 0.67 2 ? 6.0 0.2 0.013 22 11 74 .. 499 569 .. 496 589 .. 0.72 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0044 DUF6232 56 alalllgvlllalgalall.......vsvrrqprtyeLwletrgg 93 + ++lgv+++++ + + + + +r+++Lw+ +r+ FUN_001515-T1 444 WWRVVLGVIAILMT----FnlirqefMEYFASKREHRLWVKWRED 484 44444455544444....45556******************9976 PP == domain 2 score: 6.0 bits; conditional E-value: 0.013 DUF6232 11 ggqayplrnitsvrtvrgkpdrlaavgalllalalallvl.........avagsalalllgvlllalgalall 74 g++ y +++i s+r+++ p+ l+ + ++ +la al+++ + ++ + + + +l a +++++ FUN_001515-T1 499 GERMYLMQEIDSLRHQE--PSYLKDAWNFIDWLAYALIIAslaalctayLRDDHMALSVYINILSATLVVLWI 569 6799*********9999..998999999999999999999999999886333444444444444444444444 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00015 0.26 30 121 .. 185 280 .. 160 284 .. 0.77 2 ? -0.3 0.0 0.75 1.3e+03 49 84 .. 271 306 .. 258 333 .. 0.60 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00015 ANK_LRRK2 30 lkeklLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssg..vrEqdlrkaLa..vsvkrgdgevvsllLkkLgLDla 121 ++lL++a + d+ +a ll+ ga vn+ k +v + +e+v+ l+++g ++ + +++ + r+d ++ ++L k g D++ FUN_001515-T1 185 HGQTLLHEAARQWDLSVAKLLLERGAVVNQPDKYGRTPLHVAAAVDYPEMVQFLVQRGgdIHAKTVKEMQTpvHFAARNDASLSLMMLIKCGADIT 280 45789****************************999999****************99733555555543221122345666666666677776665 PP == domain 2 score: -0.3 bits; conditional E-value: 0.75 ANK_LRRK2 49 cllllgadvnkktktesliyqvCErgsplelvelll 84 l++ gad+ k ++ qv + e + l+ FUN_001515-T1 271 MLIKCGADITDKDFKQRTALQVAAELDRSETARCLI 306 466777777666666655555554444333333333 PP >> DASH_Hsk3 DASH complex subunit Hsk3 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.019 33 16 30 .. 114 128 .. 113 128 .. 0.91 2 ? 4.7 0.1 0.035 60 12 34 .. 782 804 .. 778 811 .. 0.88 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.019 DASH_Hsk3 16 aNLadteellrmtse 30 a+L+d+eel+++ts+ FUN_001515-T1 114 AQLSDLEELVEITSQ 128 89***********95 PP == domain 2 score: 4.7 bits; conditional E-value: 0.035 DASH_Hsk3 12 aqLqaNLadteellrmtseQaes 34 +L + L+++e++ r+ s+Q+ s FUN_001515-T1 782 HKLREDLKKLEQQQRVFSSQFHS 804 6899****************976 PP >> Tup_N Tup N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 7.5 1.3e+04 6 15 .. 458 467 .. 457 476 .. 0.73 2 ? 10.3 5.8 0.00058 0.99 15 73 .. 755 813 .. 743 815 .. 0.89 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 7.5 Tup_N 6 LdaikqEfdn 15 +++i+qEf + FUN_001515-T1 458 FNLIRQEFME 467 5678888864 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00058 Tup_N 15 nlsqeasslkaqkdeyelkvnsqiqElqqirqtlyeLeeahrkikqqYEeeiarLkaeL 73 ++ + ++++++q+ + +k n ++++++r+ l Le+++r q+ +i+++k L FUN_001515-T1 755 QVDHIYTHINEQESDRKRKSNGSSNDVHKLREDLKKLEQQQRVFSSQFHSQISEVKDML 813 555667788999999999***********************************999876 PP >> End3 Actin cytoskeleton-regulatory complex protein END3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.24 4.2e+02 22 56 .. 115 150 .. 99 162 .. 0.81 2 ? 8.8 4.5 0.0015 2.6 42 106 .. 741 804 .. 730 812 .. 0.80 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.24 End3 22 eLaeLeeklekveeeaekr.esnreessksalvkre 56 +L +Lee++e +++e++++ ++ ++ ss s+ + + FUN_001515-T1 115 QLSDLEELVEITSQEKHRKdGGVSSVSSPSRALLYY 150 89***********99998876666666666666555 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0015 End3 42 snreessksalvkreleqLLkYKeeqlreleegegkskeknlksvkeDietveeQVdgLesyLss 106 +++e + ++++k++ + ++++ +eq ++ + +++ s ++++++++eD++++e+Q ++ s +s FUN_001515-T1 741 EEKELQRMTHQIKEQVDHIYTHINEQESDRKRKSNGS-SNDVHKLREDLKKLEQQQRVFSSQFHS 804 45566677899***********999999888887665.599**************8877766555 PP >> Hep_59 Hepatocellular carcinoma-associated antigen 59 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.2 2.2 3.8e+03 32 60 .. 25 53 .. 9 72 .. 0.58 2 ? 10.4 3.5 0.00069 1.2 21 83 .. 743 810 .. 740 816 .. 0.67 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 2.2 Hep_59 32 eeeeeeekeaekskksedpeeelyklpek 60 ee+++++a++++ ++d++e+l+ lp++ FUN_001515-T1 25 VVEENRGAQASSATHNSDEKESLQILPQR 53 33444555555555555555556666654 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00069 Hep_59 21 eeLakrkgk.....ekeeeeeeekeaekskksedpeeelyklpeklkvkkeeeeelseqmltgIpEVd 83 +eL++++ + ++ + +e+e++++ ks+ +++++ kl e+lk+ +++++ s+q +++I+EV+ FUN_001515-T1 743 KELQRMTHQikeqvDHIYTHINEQESDRKRKSNGSSNDVHKLREDLKKLEQQQRVFSSQFHSQISEVK 810 5666644444444322223334445555555555566678899999998999999***********95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (828 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2321 (0.0908593); expected 510.9 (0.02) Passed bias filter: 1012 (0.0396164); expected 510.9 (0.02) Passed Vit filter: 129 (0.00504991); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.48u 0.38s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 7904.24 // Query: FUN_001517-T1 [L=531] Description: FUN_001517 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-38 133.1 0.0 2.5e-38 131.9 0.0 1.6 2 DEAD DEAD/DEAH box helicase 1.7e-17 64.1 0.5 4.9e-16 59.4 0.5 3.0 2 Helicase_C Helicase conserved C-terminal domain 3.2e-10 40.6 0.0 2.1e-09 38.0 0.0 2.3 2 ResIII Type III restriction enzyme, res subunit Domain annotation for each model (and alignments): >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 131.9 0.0 2.9e-42 2.5e-38 1 165 [. 20 192 .. 20 194 .. 0.87 2 ? -3.6 0.0 1.4 1.2e+04 116 128 .. 280 292 .. 263 317 .. 0.65 Alignments for each domain: == domain 1 score: 131.9 bits; conditional E-value: 2.9e-42 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.x.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxx RF DEAD 1 tpiQaeaipallegkdvlvqapTGsGKTlafllpileal.k.....kkkegpqalvlaPtreLaeqiveelkkllkk..lglkvasllggdsrkeq 88 +piQ++aip +legkd+l++a+TGsGKT+a+++p+++++ + +++g +alvl+P +eLa+q +++lk+l + +++v+ + +g+ + FUN_001517-T1 20 SPIQENAIPLALEGKDILARAKTGSGKTAAYAIPLIQRIlQdkqgdPSSSGVRALVLVPSKELAKQAHRNLKELSLYcsRDVRVTDVAQGNLS-ST 114 59*************************************87999988999************************9984355677655555555.45 PP xxxx.xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF DEAD 89 lekl.kkadilvgtpgrlldlleerkk..lknlkllvlDEahrlldkgfgeqleeilrrlklpkkrqilllSATlpkeve 165 ++ l +++di+vgtp+ ll +l+ ++ +l++lv+DEa+ + + g++++l+ +l++l pk +q l+SAT++++v FUN_001517-T1 115 KSLLmESPDIVVGTPSVLLGHLQAKNLdlKVSLEMLVIDEADLVFSYGYESDLKVLLSHL--PKIYQAFLMSATFSEDVS 192 5555488***************444447455789**************************..999**********98876 PP == domain 2 score: -3.6 bits; conditional E-value: 1.4 xxxxxxxxxxxxx RF DEAD 116 knlkllvlDEahr 128 +n +l ++DE+ r FUN_001517-T1 280 HNSRLHIVDEFNR 292 4556666666544 PP >> Helicase_C Helicase conserved C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 0.59 5.1e+03 13 34 .. 68 90 .. 55 110 .. 0.74 2 ! 59.4 0.5 5.7e-20 4.9e-16 4 108 .. 232 362 .. 229 364 .. 0.91 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.59 Helicase_C 13 eeggkvlifvqtkkelel.aell 34 ++g ++l+ v++k+ +++ + l FUN_001517-T1 68 SSGVRALVLVPSKELAKQaHRNL 90 67889999999999887554444 PP == domain 2 score: 59.4 bits; conditional E-value: 5.7e-20 Helicase_C 4 eallell.ekeeggkvlifvqtkkelelaelllekegikvarlhgdlsqeereeilekfrkgkikvLvatdv........................ 74 +++ ll k +gk+++fv+ ++++ +++l+le+ ik+++l+++l+++ r +i+++f+++ ++ ++a+d FUN_001517-T1 232 LLIYTLLkLKLVQGKTILFVNGINKCYRLKLFLEQFSIKACVLNSELPHNSRLHIVDEFNRDIYDYIIASDEsvfdavsssqtngkkkkrekdkey 327 5566666778899*************8899998999************************99999****998889999999999999999999999 PP Helicase_C 75 .aerGldlpdvdlvinydlpwnpasyiQriGRagR 108 ++rG+d+++v+ vin+d+p +++ yi+r+GR++R FUN_001517-T1 328 gVSRGVDFQGVENVINFDFPPTVDAYIHRVGRTAR 362 9999******************************9 PP >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 0.0 2.4e-13 2.1e-09 22 134 .. 32 155 .. 9 189 .. 0.78 2 ? -1.2 0.1 0.28 2.4e+03 63 95 .. 378 417 .. 365 452 .. 0.62 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 2.4e-13 ResIII 22 gekrglivmaTGsGKTlva.akliarlskkgkek......kvlflvdrkeLleqakeefkkflseekke......ageilsgdkkkeekkekkivv 104 + k +l + TGsGKT + + li+r+ + ++ + ++l+lv++keL++qa++++k+++ ++++ a+++ls+ k ++ +ivv FUN_001517-T1 32 EGKDILARAKTGSGKTAAYaIPLIQRILQDKQGDpsssgvRALVLVPSKELAKQAHRNLKELSLYCSRDvrvtdvAQGNLSSTKSLL-MESPDIVV 126 56789999********998689****999877779************************9999988877875555444444444444.7999**** PP ResIII 105 ttiqslskalekekeellkdkfdviiiDEa 134 t + l +l ++k+ lk + ++++iDEa FUN_001517-T1 127 GTPSVLLGHL-QAKNLDLKVSLEMLVIDEA 155 **********.9999999999********9 PP == domain 2 score: -1.2 bits; conditional E-value: 0.28 ResIII 63 keLleqakeefkkflseekke.......ageilsgdkkke 95 +Ll++a+e++ ++ ekke ++e+++g +++ FUN_001517-T1 378 HKLLKKAEEKLAAEFPGEKKEifkqyqfKMEEIEGFRYRA 417 4788888888877777776554443333444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (531 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 953 (0.0373067); expected 510.9 (0.02) Passed bias filter: 696 (0.027246); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5065.04 // Query: FUN_001518-T1 [L=254] Description: FUN_001518 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00041 20.7 0.5 0.0012 19.1 0.5 1.9 1 DJ-1_PfpI DJ-1/PfpI family ------ inclusion threshold ------ 0.17 12.4 0.0 0.3 11.6 0.0 1.4 1 Phage-A118_gp45 Protein gp45 of Bacteriophage A118 Domain annotation for each model (and alignments): >> DJ-1_PfpI DJ-1/PfpI family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.5 9.6e-08 0.0012 7 119 .. 42 181 .. 34 227 .. 0.80 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 9.6e-08 DJ-1_PfpI 7 ladgvedvElvvpadvlkragikvtvvsle..........keevkgsrGvkvlvdasle.........dvkaeeydalvlpGGragperlre.... 79 ++dg+e E++ + l+rag +v++ +++ k+ev++ + +vlv+ + d+++ ++da+v pGG +++l+ FUN_001518-T1 42 VFDGTEIHEASAVLVHLSRAGADVSIYAPDipqmhvlnhaKGEVTEGETRNVLVESARIargkisslaDLDVTSHDAVVFPGGFGAAKNLSSfage 137 5788999999999999999999999999999999999888777777777777776543347777777799***************99999753333 PP DJ-1_PfpI 80 ......neklvelvkefaekgklvaaICagpqvLaaagvlkgrkvT 119 n+ +++ + f+ +k+++ C +p++ aa+v+ g ++T FUN_001518-T1 138 gtgckvNKDVQQAITAFHVAKKPIGLCCIAPVL--AAKVIPGVEIT 181 33332256899999999999********99864..55666666666 PP >> Phage-A118_gp45 Protein gp45 of Bacteriophage A118 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 2.3e-05 0.3 16 48 .. 215 249 .. 207 254 .] 0.81 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.3e-05 Phage-A118_gp45 16 eifvddltkmianPafr..qkialietGcekmtdy 48 ei+vd+ k+++ Paf k+ + G km + FUN_001518-T1 215 EIHVDEENKVVTTPAFMceTKVHEVHDGVGKMIEA 249 9***************6225777788899999765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (254 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 617 (0.0241535); expected 510.9 (0.02) Passed bias filter: 513 (0.0200822); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2487.92 // Query: FUN_001519-T1 [L=488] Description: FUN_001519 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-13 50.9 14.9 3e-13 50.1 14.9 1.4 1 bZIP_1 bZIP transcription factor 8.1e-09 35.9 10.9 1.4e-08 35.1 10.9 1.4 1 bZIP_2 Basic region leucine zipper 5.5e-05 24.1 8.2 0.0001 23.3 8.2 1.4 1 bZIP_Maf bZIP Maf transcription factor ------ inclusion threshold ------ 0.011 16.5 3.4 0.023 15.5 3.4 1.5 1 CC_Bre1 Bre1, coiled-coil containing domain 0.027 15.0 4.6 0.053 14.1 4.6 1.4 1 Myo5a Unconventional myosin-Va domain 0.05 13.5 0.0 0.14 12.1 0.0 1.8 1 GIDE E3 Ubiquitin ligase 0.16 12.6 0.4 0.31 11.6 0.4 1.4 1 TolA_bind_tri TolA binding protein trimerisation 0.21 12.4 8.4 0.36 11.6 8.4 1.3 1 Rab11-FIP3 Rab11-FIP3-like domain 1.8 9.7 3.5 4.4 8.5 0.7 2.3 2 DUF4404 Domain of unknown function (DUF4404) 5 7.0 9.4 0.32 10.9 3.8 1.8 3 HAUS-augmin3 HAUS augmin-like complex subunit 3 Domain annotation for each model (and alignments): >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.1 14.9 1.2e-16 3e-13 1 59 [. 284 342 .. 284 350 .. 0.95 Alignments for each domain: == domain 1 score: 50.1 bits; conditional E-value: 1.2e-16 bZIP_1 1 ekelKrekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekL 59 e++lK+ +rk+kN+++A++sR++K++++e Le+rv+ + eN +L++++++l+ ++ +L FUN_001519-T1 284 ERALKKVRRKIKNKISAQESRRKKKEYMETLEKRVENCSCENLELRKKVDSLESTNRSL 342 799**************************************************999887 PP >> bZIP_2 Basic region leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.1 10.9 5.5e-12 1.4e-08 5 52 .. 288 336 .. 284 338 .. 0.96 Alignments for each domain: == domain 1 score: 35.1 bits; conditional E-value: 5.5e-12 bZIP_2 5 yrerRr.kNneAAkrsRekkkqkeeeleervkeLekeNarLrqkveqle 52 +++rR+ kN ++A+ sR kkk+++e le+rv++ eN +Lr+kv++le FUN_001519-T1 288 KKVRRKiKNKISAQESRRKKKEYMETLEKRVENCSCENLELRKKVDSLE 336 799********************************************98 PP >> bZIP_Maf bZIP Maf transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 8.2 3.9e-08 0.0001 21 92 .] 279 350 .. 277 350 .. 0.94 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 3.9e-08 bZIP_Maf 21 lteeeverLKqrRRrlKNrgyakscrkrrlqqkeelekekekleeelerlkqelsrlrqekdalkrkneqlq 92 lt+ e LK+ RR+ KN+ a+++r+++ + e+lek e+ + e+ +l+++++ l+ + +l ++ ++lq FUN_001519-T1 279 LTKVEERALKKVRRKIKNKISAQESRRKKKEYMETLEKRVENCSCENLELRKKVDSLESTNRSLIGQLQKLQ 350 56777789****************************************************999999999886 PP >> CC_Bre1 Bre1, coiled-coil containing domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 3.4 9.1e-06 0.023 53 127 .. 280 350 .. 257 355 .. 0.85 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 9.1e-06 CC_Bre1 53 edseefeehLqerskaikslvsrllaskrgksspdveelqsrlakllaeekelrselerlrsekeqleeqletas 127 ++ e e +L++ +++ik+++s+ ++r k+++ +e+l++r+++ e+ elr ++++l+s +++l ql++++ FUN_001519-T1 280 TKVE--ERALKKVRRKIKNKISAQ--ESRRKKKEYMETLEKRVENCSCENLELRKKVDSLESTNRSLIGQLQKLQ 350 5544..689**************9..556678999************************************9987 PP >> Myo5a Unconventional myosin-Va domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 4.6 2.1e-05 0.053 23 109 .. 285 370 .. 279 377 .. 0.84 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 2.1e-05 Myo5a 23 reLEqerkklqselekkeeqeskkvkeeekeseleeeeeaelayeslkrqeLeseNkklkndLneLrkaladkaseensseeaqdsy 109 r L + r+k+++++ ++e+ ++kk e+ e+++e+ + ++l+ k +Les+N+ l +L++L+ +a+k + ++ ++q s FUN_001519-T1 285 RALKKVRRKIKNKISAQESRRKKKEYMETLEKRVENCSCENLEL-RKKVDSLESTNRSLIGQLQKLQSIIAAKVPRTVTARSTQTST 370 568899*************9999988888888898877777766.57999********************99988888777776554 PP >> GIDE E3 Ubiquitin ligase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 5.4e-05 0.14 106 136 .. 239 268 .. 220 270 .. 0.87 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 5.4e-05 GIDE 106 sdedgelriqkpkekgqpFfisekseeeLie 136 + ++ ++iq+p+e +qpF+++e+ +++L++ FUN_001519-T1 239 TGGTTPPVIQRPQE-KQPFYLTEEERRTLVA 268 4556689*******.6********9999976 PP >> TolA_bind_tri TolA binding protein trimerisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.4 0.00012 0.31 6 45 .. 311 350 .. 308 355 .. 0.93 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00012 TolA_bind_tri 6 larLErilearnqallelqqqleqLqqevaeLRGqiEelq 45 ++ LE+ +e+ + +lel +++++L++ +++L Gq+++lq FUN_001519-T1 311 METLEKRVENCSCENLELRKKVDSLESTNRSLIGQLQKLQ 350 689**********************************998 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 8.4 0.00014 0.36 35 99 .. 288 354 .. 279 368 .. 0.79 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00014 Rab11-FIP3 35 eeeqrrhrealsrle..RekelelenlqaRlqqleeEnseLrsevprlkaqlerleeekqklqdele 99 ++ +r+ ++ +s +e R+k+ +e+l++R+++ En eLr++v+ l ++ + l + qklq+ ++ FUN_001519-T1 288 KKVRRKIKNKISAQEsrRKKKEYMETLEKRVENCSCENLELRKKVDSLESTNRSLIGQLQKLQSIIA 354 3344444555544433399999***************************************998765 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.7 0.0017 4.4 17 58 .. 278 319 .. 273 325 .. 0.85 2 ? 1.3 0.1 0.3 7.5e+02 7 43 .. 327 363 .. 324 374 .. 0.78 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0017 DUF4404 17 sldeetrakLeelaedieellaeedaaaeekelvdrlneave 58 +l + ++ L++++++i+++++ ++++ ++ke +++l++ ve FUN_001519-T1 278 PLTKVEERALKKVRRKIKNKISAQESRRKKKEYMETLEKRVE 319 667778899*********************998888877766 PP == domain 2 score: 1.3 bits; conditional E-value: 0.3 DUF4404 7 kLheeLeedesldeetrakLeelaedieellaeedaa 43 +L+++++ es++ + ++L++l++ i +++ + +a FUN_001519-T1 327 ELRKKVDSLESTNRSLIGQLQKLQSIIAAKVPRTVTA 363 6899999999999999999999998888776665555 PP >> HAUS-augmin3 HAUS augmin-like complex subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 0.0 4.7 1.2e+04 159 187 .. 56 86 .. 51 87 .. 0.72 2 ? -2.9 0.1 2.1 5.3e+03 196 225 .. 162 191 .. 159 207 .. 0.60 3 ? 10.9 3.8 0.00013 0.32 54 112 .. 296 355 .. 280 371 .. 0.80 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 4.7 HAUS-augmin3 159 Lasffsase..ppvfLsqlsLekYlsqeeqf 187 L+ ff++ Ls+ sL +Y s+ ++ FUN_001519-T1 56 LSRFFDDVPacADSSLSYNSLPEYTSSSLSC 86 5666665556666669999999999988776 PP == domain 2 score: -2.9 bits; conditional E-value: 2.1 HAUS-augmin3 196 kkqFkqGiselveesneekfqlldlsksse 225 ++ F + + + e +n ++f+ +++k s FUN_001519-T1 162 QEGFTSQMNSYIEPENLKMFEQNEIRKNSP 191 555666666666666666666666666665 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00013 HAUS-augmin3 54 ktiea.spsdlkqedveeleesleeieealedleaelqeLqkekqlkinrlnkLqlaass 112 ++i+a +++++k+e e le+ +e+ + +l++ ++ L+ +++++i +l+kLq+ +++ FUN_001519-T1 296 NKISAqESRRKKKEYMETLEKRVENCSCENLELRKKVDSLESTNRSLIGQLQKLQSIIAA 355 3567767777777999***************************************98875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (488 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1916 (0.0750049); expected 510.9 (0.02) Passed bias filter: 1089 (0.0426307); expected 510.9 (0.02) Passed Vit filter: 126 (0.00493247); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.37u 0.42s 00:00:00.79 Elapsed: 00:00:00.41 # Mc/sec: 4801.24 // Query: FUN_001520-T1 [L=373] Description: FUN_001520 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-07 29.1 0.2 8.6e-07 29.1 0.2 2.3 4 SPMIP4-like Sperm-associated microtubule inner protein 4 ------ inclusion threshold ------ 0.31 12.0 0.4 0.92 10.5 0.4 1.9 1 YtxH YtxH-like protein Domain annotation for each model (and alignments): >> SPMIP4-like Sperm-associated microtubule inner protein 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 0.11 1.4e+03 19 32 .. 12 25 .. 2 35 .. 0.77 2 ! 29.1 0.2 6.7e-11 8.6e-07 92 167 .. 61 130 .. 49 156 .. 0.76 3 ? -3.3 0.1 0.52 6.6e+03 160 180 .. 276 297 .. 263 349 .. 0.56 4 ? -2.7 0.0 0.34 4.3e+03 39 70 .. 334 368 .. 300 372 .. 0.66 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.11 SPMIP4-like 19 iLsrtfesnevltP 32 +s+tf s ++ltP FUN_001520-T1 12 RISPTFLSSDLLTP 25 489**********9 PP == domain 2 score: 29.1 bits; conditional E-value: 6.7e-11 SPMIP4-like 92 hkhyGsgvepfprklpieqfYdltqnkksdvrknDsLlpkPpssavkelclpfpiehPyqthisrlalfPtftsPk 167 ++hy sgv + + q Y + + d r D+Llp P +++ ++l p+p hPy +hi r+ +fP f s + FUN_001520-T1 61 YRHYSSGVYN---NDTASQPYAVDSL--NDCRIHDQLLPAPFKTKHEKLEEPWP-GHPYTSHICRCEVFPRFDSGR 130 4566666543...3345688877655..577788********************.6****************9864 PP == domain 3 score: -3.3 bits; conditional E-value: 0.52 SPMIP4-like 160 fPtftsPkdldtgldassq.qp 180 +P+f Pk + ++ ++q q FUN_001520-T1 276 YPKFPLPKYSTLNFAKRNQlQD 297 5555555555444444444322 PP == domain 4 score: -2.7 bits; conditional E-value: 0.34 SPMIP4-like 39 etvsedrYre.lreslrack..lpwGaereygGiv 70 +t +++rY+e +++ + + l G+++ + G+ FUN_001520-T1 334 KTEAHKRYHEiYYDAVPDLRdsLKTGRQHFFWGVH 368 67777788773456665555235566666666655 PP >> YtxH YtxH-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.4 7.2e-05 0.92 24 69 .. 139 197 .. 133 199 .. 0.85 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 7.2e-05 YtxH 24 ketRkklkkkaedlkdkleelleea.............kekaedlkekvkekadelkek 69 +++R++l ++ d+ + l + ++ + +e+a+++++k ++k+de ek FUN_001520-T1 139 RKLRQQLCSSTRDALEHLSKKIYCTseykdsmkatvefQETAAEYQQKGENKVDEFHEK 197 79999999999999887766655559999999999999***************998775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (373 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1438 (0.0562928); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3638.15 // Query: FUN_001521-T1 [L=348] Description: FUN_001521 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-40 140.2 19.2 1.1e-40 140.2 19.2 1.3 2 7tm_1 7 transmembrane receptor (rhodopsin family) 2.8e-07 30.7 16.8 4.9e-07 29.9 16.8 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.28 11.4 4.0 0.76 10.0 4.0 1.8 1 FA_desaturase Fatty acid desaturase Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.2 1 8.7e+03 103 118 .. 28 43 .. 23 44 .. 0.64 2 ! 140.2 19.2 1.3e-44 1.1e-40 1 260 [] 45 304 .. 45 304 .. 0.91 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 1 xxxxxxxxxxxxxxxx RF 7tm_1 103 lvlilvvWvlalllsl 118 ++++ vv++l +l+sl FUN_001521-T1 28 ITIVTVVYALTMLVSL 43 4566667777777665 PP == domain 2 score: 140.2 bits; conditional E-value: 1.3e-44 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvf....gevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+++i+++++ + r+ t++ ++n+avaDl v+++++p+++++ +wv+ g++ C++v ++ ++++asil+lt+++iDR+ +I pl FUN_001521-T1 45 GNCCLIYLVWKVYETRSLTSFMFVNMAVADLFVTIIMMPLTTSEMNNDFGWVVsgtfGDISCRAVQYISKTAIMASILSLTFMAIDRFYVIKFPLV 140 8*****************************************9998999997444449999*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkek 188 + r+ r+ +++ ++W+l++ l+ ++ ++ k +e +Cl++ + + + + ++l+++++l+pl +i+++y + ++t++ +++ + FUN_001521-T1 141 S-RVAWFRKSKFISPLIWLLSMSLMSIMPVVYFLK-----EEGPECLLNALGNPRVTIRGLFIYLFLVSYLIPLAIITILYGKAAHTIWFHSTPGN 230 9.67999*************997766666655554.....5689******99888899***********************************999 PP x....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 189 s....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + ++++++ ++++++++l+++v+vf++cwlP+++l l+ + + + ++ + ++t++la++ns++NP++Y FUN_001521-T1 231 RltgtQQRMEEINKKRVVRMLVIIVAVFAVCWLPIQLLHLFYAA--TLFRVSVPIVVGSLTSWLAHANSAINPWLY 304 977777777777888**********************9999998..666777777777*****************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 16.8 5.8e-11 4.9e-07 2 255 .. 40 317 .. 39 319 .. 0.74 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 5.8e-11 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltgt.......qlkreeCFlliivyvfgltaqsvllLvigiDlliav 90 +v+l+GN+ li+l+ k + rs +s + + ++adl++ + ++ + + +++ ++ C + + +++a+ + l +++iD+++++ FUN_001521-T1 40 LVSLVGNCCLIYLVWKVYETRSLTSFMFVNMAVADLFVTIIMMPLTTSEMNNDfgwvvsgTFGDISCRAVQYISKTAIMASILSLTFMAIDRFYVI 135 799***********************************9999998888775532222222666778988888888888888888889********* PP 7TM_GPCR_Srsx 91 kfPirYrllskek..Yllillifpvlyssiilvlgflqrdde......tiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek. 177 kfP+ r +k +++ l+ + + +s++ ++ +++ +e +p +++ g +f +s li i++++y + +++ ++++ FUN_001521-T1 136 KFPLVSRVAWFRKskFISPLIWL-LSMSLMS-IMPVVYFLKEegpeclLNALGNPRVTIRGLFIYLFLVSYLIPLAIITILYGKAAHTIWFHSTPg 229 ****9997655553366544433.3333332.2233333333011132333344555554444456666666666667777777766655555547 PP 7TM_GPCR_Srsx 178 ..........kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafre 255 ++ + k+v + l + v +f ++W+ ++l + a + +v ++ + +++l+ +++ n + ++ ss+ + af + FUN_001521-T1 230 nrltgtqqrmEEINKKRVVRMLVIIVAVFAVCWLPIQLLHLFYAATLFRVSVPIVVGSLTSWLAHANSAINPWLYICLSSKMKPAFLR 317 7899988887888999************************************************************999998888866 PP >> FA_desaturase Fatty acid desaturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 4.0 8.9e-05 0.76 106 186 .. 221 296 .. 182 321 .. 0.64 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 8.9e-05 FA_desaturase 106 a.wllalllllwarrlarrkrpiksrrrrwrllaalllllawlglwlallllagllll.lwllpllvllfllalvfnyleHyg 186 w+++ rl ++ +++++ +++++++++++++++++ wl++ ll+ + ++ l+ + + +++ l+ +l H+ FUN_001521-T1 221 TiWFHST----PGNRLTGTQQRMEEINKKRVVRMLVIIVAVFAVCWLPIQLLHLFYAAtLFRVSVPIVVGSLT---SWLAHAN 296 2343333....45555556666666666799999999999999999999998876665544444444444443...7777754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (348 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1072 (0.0419652); expected 510.9 (0.02) Passed bias filter: 380 (0.0148757); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3413.40 // Query: FUN_001522-T1 [L=120] Description: FUN_001522 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.1e-22 78.6 15.4 8.1e-22 78.6 15.4 1.6 2 TMEM138 Transmembrane protein 138 Domain annotation for each model (and alignments): >> TMEM138 Transmembrane protein 138 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.2 0.32 8.3e+03 47 53 .. 12 18 .. 3 31 .. 0.50 2 ! 78.6 15.4 3.2e-26 8.1e-22 2 67 .. 38 103 .. 37 118 .. 0.95 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.32 TMEM138 47 lsvlYll 53 l++l+l+ FUN_001522-T1 12 LQLLFLF 18 2222222 PP == domain 2 score: 78.6 bits; conditional E-value: 3.2e-26 TMEM138 2 lvlfilQdvllilslivlllslfsTyvfqaGlvelllekfrltlllsvlYlllsislhvwllllrw 67 l+l+i+Qdv++i+++iv++l++f+Ty+fqaGlv+ll++kf++t+++s++Yl+ls+ lhvw++++++ FUN_001522-T1 38 LLLYIIQDVCIIFAIIVVFLVFFNTYIFQAGLVSLLIRKFKTTIIISITYLALSVGLHVWTMVSSF 103 89************************************************************9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1520 (0.0595028); expected 510.9 (0.02) Passed bias filter: 334 (0.013075); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1205.19 // Query: FUN_001523-T1 [L=254] Description: FUN_001523 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0057 17.4 4.0 0.0099 16.6 4.0 1.3 1 RhlB ATP-dependent RNA helicase RhlB ------ inclusion threshold ------ 0.027 15.3 0.3 0.062 14.1 0.0 1.6 2 DUF1190 Protein of unknown function (DUF1190) 0.04 15.4 0.3 0.1 14.1 0.3 1.7 1 YxzE YxzE-like putative bacteriocin Domain annotation for each model (and alignments): >> RhlB ATP-dependent RNA helicase RhlB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 4.0 1.2e-06 0.0099 51 102 .. 22 71 .. 17 93 .. 0.85 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 1.2e-06 RhlB 51 adearrgggksgpggasrsgsgggrresagadgkprpprrkprverevdpaa 102 d + rggg+s gg srs s r s g+ kp+ + p ++ v FUN_001523-T1 22 VDARGRGGGRSS-GGRSRSSSRS-RSSSGGSSSKPKITKYTPITPTSVRSPV 71 57788******9.999***9998.******************9999887554 PP >> DUF1190 Protein of unknown function (DUF1190) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.1 0.71 6e+03 125 126 .. 45 46 .. 24 75 .. 0.47 2 ? 14.1 0.0 7.3e-06 0.062 64 147 .. 79 172 .. 68 179 .. 0.66 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.71 DUF1190 125 sv 126 s+ FUN_001523-T1 45 SS 46 11 PP == domain 2 score: 14.1 bits; conditional E-value: 7.3e-06 DUF1190 64 sgggsffmPlmaGfllgrllsggg.gyr.sqplyrsr.....srgsslrdk.........lvtasgkslgaastakrsvnvkktalkpkptvtrtv 143 + +s+f ++aG+l++r l g++ yr p+yr + + l++a+g+s ++st++ ++ ++ + + t+t t FUN_001523-T1 79 GSRTSSFSNVVAGYLVARYLFGSApVYRsGYPMYRCYvkvptE------RAlrityeeerLLNATGHSCLSSSTTNGTLIEGIDQNRTSLTTTITH 168 456899**************55555444356777775333331......22444445568889999888555555555555666667777777777 PP DUF1190 144 srgG 147 +++G FUN_001523-T1 169 KKSG 172 6665 PP >> YxzE YxzE-like putative bacteriocin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.3 1.2e-05 0.1 6 50 .. 4 51 .. 1 55 [. 0.60 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.2e-05 YxzE 6 llilvfiliiiilavltsskskkkkkrssy.d.hdsss.dsssDcgds 50 ++++fi i i+l ++ s + +++ ++s+ + ++sss + ss g+s FUN_001523-T1 4 STVVLFISIAILLIAALSVDARGRGGGRSSgGrSRSSSrSRSSSGGSS 51 456677777777777777777777777775334566664444333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (254 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1085 (0.0424741); expected 510.9 (0.02) Passed bias filter: 708 (0.0277158); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2516.50 // Query: FUN_001524-T1 [L=238] Description: FUN_001524 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.047 14.5 0.2 0.1 13.4 0.1 1.6 1 DUF1190 Protein of unknown function (DUF1190) Domain annotation for each model (and alignments): >> DUF1190 Protein of unknown function (DUF1190) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.1 4e-06 0.1 65 138 .. 64 147 .. 56 164 .. 0.60 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 4e-06 DUF1190 65 gggsffmPlmaGfllgrllsggg.gyr.sqplyrsr.....srgsslrdk.........lvtasgkslgaastakrsvnvkktalkpkpt 138 + +s+f ++aG+l++r + g++ yr p+yrs+ + l+t++g+s ++ tak ++ ++ + + t FUN_001524-T1 64 SRTSSFRNVVAGYLVARYILGNApVYRsGYPMYRSYvkvptQ------RAlrityeeerLLTSTGRSCLSSPTAKGTLIEGIDQNRTSLT 147 56899************99655565554789**996433331......323444445677777777664455555444434444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (238 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 799 (0.0312781); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2420.05 // Query: FUN_001525-T1 [L=144] Description: FUN_001525 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 864 (0.0338227); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.34s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1447.63 // Query: FUN_001527-T1 [L=398] Description: FUN_001527 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-46 159.7 15.6 1.7e-46 159.3 15.6 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.9e-05 24.7 14.2 2.8e-05 24.1 14.2 1.2 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.054 14.0 1.3 0.054 14.0 1.3 2.6 2 DUF7471 Family of unknown function (DUF7471) 0.11 13.2 0.5 0.25 12.0 0.5 1.6 1 Pox_A28 Poxvirus A28 family 0.22 12.0 0.1 0.22 12.0 0.1 3.0 4 CBU_0592 CBU_0592 family Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.3 15.6 3.3e-50 1.7e-46 1 260 [] 54 313 .. 54 313 .. 0.93 Alignments for each domain: == domain 1 score: 159.3 bits; conditional E-value: 3.3e-50 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN+l+i++i+r+ k r++++++++nLa Dll+++l++pf ++ l+ ++w+fg +lCklv+ l++v++ +s+++l++++++R+ ++++plk + FUN_001527-T1 54 GNMLLIIAIARTPK-RKTSQYLIVNLAAVDLLTCALSIPFDIAILLIDSGWPFGLALCKLVYPLQTVFMAVSVFTLLFMALERHHVMIHPLKP--K 146 8************9.777899************************************************************************..8 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx... RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks... 189 ++ l+ i ++W++++ ++ p + ++ C ++p+++ +++++tl+++++ ++ pl++i++ y+ri +lr+ + ++++ FUN_001527-T1 147 MSGNMILLAITFIWIVSIGMVSPYSAALQ-------INQGNCIENWPNNDVIYPKIFTLCVFFILYIGPLFIISIAYARIGLRLRAVEDTNATkcf 235 9**********************988665.......56789*******8888***************************************99999 PP ........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ........kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + +++++++ +++k ++ v++f++c +P++++ +++ + + ++ + +t+l++++++ y+ns++NP+i+ FUN_001527-T1 236 igckslrdSLRQREKQNIRVVKFFVIAVIAFAFCLMPFQVMWMWSDF-GNGQNWEHFNTLLTFANVMVYANSAVNPFIF 313 999998653333333444****************************9.99***************************95 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 14.2 5.6e-09 2.8e-05 1 249 [. 48 320 .. 48 322 .. 0.79 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 5.6e-09 7TM_GPCR_Srsx 1 lvvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvlll...tgtqlkreeCFlliivyvfgltaqsvllLvigiDlliavkfP 93 +vvG+iGN+lli+++++++k r s++Li+ +++ dll + +++f + l +g ++ + C l+ + +++++++ lL++++ + + P FUN_001527-T1 48 IVVGTIGNMLLIIAIARTPK-RKTSQYLIVNLAAVDLLTCALSIPFDIAILlidSGWPFGLALCKLVYPLQTVFMAVSVFTLLFMALERHHVMIHP 142 69*****************9.66689*******************99866622234578899********************************** PP 7TM_GPCR_Srsx 94 irYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkas.eiftlsslii...n..vivllvylvliiilkkkkek...... 177 ++ + + l+i++i v ++ ++ lq+++ + C ++ + +iftl +++i i+ + y+ + + l+ +++ FUN_001527-T1 143 LKPKMSGNMILLAITFIWIVSIGMVSPYSAALQINQGN---CIENWPNNDVIYpKIFTLCVFFIlyiGplFIISIAYARIGLRLRAVEDTnatkcf 235 ***99999989999999999999999999999999985...4444444444443555555444411122134555566666667777666999*** PP 7TM_GPCR_Srsx 178 ............kkssskkvlkslkvtvvififgWftstilntvl.lalteseevekliqayagilvllsfsqnffVtywrsseY 249 ++++ +v k + v+ f f+ + +++ + + + ++ e + + + a ++v +++ n f++ ++ ++Y FUN_001527-T1 236 igckslrdslrqREKQNIRVVKFFVIAVIAFAFCLMPFQVMWMWSdFGNGQNWEHFNTLLTFANVMVYANSAVNPFIFGAIGRRY 320 *********99888888899999999999999999988888776623444555555667888999999999********999999 PP >> DUF7471 Family of unknown function (DUF7471) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 1.3 1.1e-05 0.054 3 44 .. 44 84 .. 42 90 .. 0.87 2 ? 2.1 0.4 0.054 2.8e+02 47 78 .. 118 151 .. 106 160 .. 0.64 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.1e-05 DUF7471 3 llavlllaavgtavllalalaaylrrrsrryllvalalgaLv 44 ++a+++++++g + ll +a+a +r++++yl+v la L+ FUN_001527-T1 44 YAAIIVVGTIGNM-LLIIAIARTPKRKTSQYLIVNLAAVDLL 84 5789999999987.8899*****************9987776 PP == domain 2 score: 2.1 bits; conditional E-value: 0.054 DUF7471 47 svvglltvlglvpe..ttHHlveHgldvliaalv 78 +v +++v+ l+ + + HH++ H l +++ + FUN_001527-T1 118 TVFMAVSVFTLLFMalERHHVMIHPLKPKMSGNM 151 555556666665541168******9988777643 PP >> Pox_A28 Poxvirus A28 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.5 5e-05 0.25 3 48 .. 255 300 .. 253 310 .. 0.89 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5e-05 Pox_A28 3 avsillivlataavcllllqlyaiyenydnikefndaysaleysks 48 +v+ ++i +++ a cl+ +q+ ++++++n +++ + ++ l ++ FUN_001527-T1 255 VVKFFVIAVIAFAFCLMPFQVMWMWSDFGNGQNWEHFNTLLTFANV 300 68899*************************9999999999999875 PP >> CBU_0592 CBU_0592 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 4.4e-05 0.22 3 61 .. 49 103 .. 47 117 .. 0.89 2 ? -0.4 0.0 0.33 1.7e+03 57 72 .. 116 131 .. 111 135 .. 0.82 3 ? -3.0 0.3 2.2 1.1e+04 51 63 .. 150 162 .. 147 170 .. 0.64 4 ? -3.5 0.4 3.1 1.6e+04 7 53 .. 264 269 .. 258 278 .. 0.41 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 4.4e-05 CBU_0592 3 iiGliGvalillaYallqlgklsgdsllyqllNllGAalllisllvnfnlpsfvlevvW 61 ++G+iG +l+++a a + +k s+ y ++Nl++ ll+ l++ f+++ +++ + W FUN_001527-T1 49 VVGTIGNMLLIIAIARTPKRKTSQ----YLIVNLAAVDLLTCALSIPFDIAILLIDSGW 103 79**********988888887777....***************************9999 PP == domain 2 score: -0.4 bits; conditional E-value: 0.33 CBU_0592 57 levvWilislvglvkl 72 l++v++++s++ l+ + FUN_001527-T1 116 LQTVFMAVSVFTLLFM 131 7999******999765 PP == domain 3 score: -3.0 bits; conditional E-value: 2.2 CBU_0592 51 nlpsfvlevvWil 63 n+ + + ++Wi+ FUN_001527-T1 150 NMILLAITFIWIV 162 5566667777765 PP == domain 4 score: -3.5 bits; conditional E-value: 3.1 CBU_0592 7 iGvalillaYallqlgklsgdsllyqllNllGAalllisllvnfnlp 53 i f++ FUN_001527-T1 264 IA-----------------------------------------FAFC 269 22.........................................2222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (398 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1070 (0.0418869); expected 510.9 (0.02) Passed bias filter: 507 (0.0198473); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 3841.81 // Query: FUN_001528-T1 [L=372] Description: FUN_001528 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-42 146.6 8.6 1.6e-42 146.2 8.6 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 6.1e-06 26.3 6.9 6.7e-06 26.2 6.3 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.046 13.8 0.0 0.14 12.2 0.0 1.9 1 DUF6346 Family of unknown function (DUF6346) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 146.2 8.6 1.9e-46 1.6e-42 1 260 [] 43 299 .. 43 299 .. 0.89 Alignments for each domain: == domain 1 score: 146.2 bits; conditional E-value: 1.9e-46 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN+++i++++ ++ r++ ++++lnLav+Dl+++++++pf l++ l +g+++fg++lC l++ l++v++ +s+++l+ +s++R+ +++ pl+ + FUN_001528-T1 43 GNGMIIITLIG-RQTRRVGEYLILNLAVTDLATCAISIPFDLAERL-SGGFPFGSILCYLIYPLQTVLIAVSVITLLSMSLERHRVVMTPLRP--R 134 78888888776.6679******************************.7*********************************************..7 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx... RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks... 189 + +r a++ i++ Wv+ +++++p +l+ + e + C+ ++pe +++ +++tl ++l++++pl+vi+++y+r r++rk+ + ++ FUN_001528-T1 135 VLPRTAKIAIVISWVVPCTVIVPYALVLRV-------EGKHCMEKWPE--DWYVKVFTLTNFALFYVVPLTVIAFSYIRAGRKIRKELQCLENmme 221 89************************7754.......5689*******..455566666666666666*******************999988777 PP ........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 ........kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++k++ ++ +++k+ +v v +f++c+lP + +++ + + +++k + +l+++++++y+ns+ NP+i+ FUN_001528-T1 222 ethrsqvsYSRKRTLQKMRITKVFIVAVSAFLVCMLPTHASWIWHDF-GHGRDSKYFKDVLIFSNIFMYANSASNPFIF 299 777666653334444445****************************9.99***************************95 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 6.3 7.9e-10 6.7e-06 2 196 .. 38 247 .. 37 305 .. 0.67 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 7.9e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv.lllt.gtqlkreeCFlliivyvfgltaqsvllLvigiDlliavkfPir 95 ++GliGN +i++t+ ++ r ++Li +++ dl + +++f + +l+ g ++ + C+l+ + ++ ++++ + lL++ + + +v+ P+r FUN_001528-T1 38 IIGLIGNG-MIIITLIGRQTRRVGEYLILNLAVTDLATCAISIPFDLaERLSgGFPFGSILCYLIYPLQTVLIAVSVITLLSMSLERHRVVMTPLR 132 8******8.66677888889999*************99999998876455642679999************************************* PP 7TM_GPCR_Srsx 96 YrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlsslii.nvivllvylvliiilkkkkek............. 177 r l+++ ++i++ +v +++i+ + +l ++ + C+ + ++ftl+++++ +v+ l v ++++i + +k k FUN_001528-T1 133 PRVLPRTAKIAIVISWVVPCTVIVPYALVLRVEGK---HCMEKWPE-DWYVKVFTLTNFALfYVVPLTVIAFSYIRAGRKIRKelqclenmmeeth 224 *********************99998888888777...56554443.3333455555554413333455566666655544444567777777777 PP 7TM_GPCR_Srsx 178 .........kkssskkvlkslkvt.vvif 196 + +l+++ +t v+i+ FUN_001528-T1 225 rsqvsysrkR------TLQKMRITkVFIV 247 7775443222......2222222213333 PP >> DUF6346 Family of unknown function (DUF6346) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 1.7e-05 0.14 92 143 .. 204 257 .. 195 259 .. 0.88 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.7e-05 DUF6346 92 diGkevrv.laikdggetetsrgkrelaRaeela.rpvltllglvvgvlgvlaa 143 G+++r l++ ++ +et+r + +++R +l+ +++++++ ++v++++v ++ FUN_001528-T1 204 RAGRKIRKeLQCLENMMEETHRSQVSYSRKRTLQkMRITKVFIVAVSAFLVCML 257 5799999999********************9985389999********999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (372 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1063 (0.0416128); expected 510.9 (0.02) Passed bias filter: 519 (0.0203171); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3698.32 // Query: FUN_001529-T1 [L=778] Description: FUN_001529 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-42 146.5 0.0 1.7e-42 145.9 0.0 1.3 1 DAGK_acc Diacylglycerol kinase accessory domain 3.8e-28 98.1 0.0 7.6e-28 97.1 0.0 1.5 1 DAGK_cat Diacylglycerol kinase catalytic domain 3.4e-26 92.1 0.0 1.4e-13 51.7 0.0 2.3 3 Ank_2 Ankyrin repeats (3 copies) 8.6e-23 81.2 0.3 1.7e-22 80.3 0.3 1.5 1 DGKI Diacylglycerol kinase iota-like domain 1.2e-11 45.0 0.0 0.00042 21.1 0.0 3.0 3 Ank_4 Ankyrin repeats (many copies) 1.7e-11 44.1 0.0 0.00046 20.9 0.0 3.5 3 Ank Ankyrin repeat 1.3e-09 37.8 0.0 0.0011 19.7 0.0 2.9 2 Ank_3 Ankyrin repeat 1.8e-07 31.9 0.0 3.7e-05 24.5 0.0 2.7 3 Ank_5 Ankyrin repeats (many copies) ------ inclusion threshold ------ 0.019 14.9 0.0 0.064 13.2 0.0 1.9 1 MOV-10_beta-barrel Helicase MOV-10, beta-barrel domain Domain annotation for each model (and alignments): >> DAGK_acc Diacylglycerol kinase accessory domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.9 0.0 6.1e-46 1.7e-42 1 158 [] 233 390 .. 233 390 .. 0.96 Alignments for each domain: == domain 1 score: 145.9 bits; conditional E-value: 6.1e-46 DAGK_acc 1 vmnNYfsiGvDAkialeFheaReekPelfnsrlvnKliYlklglkkllkkslknlkekvelevdgkev..elp.kkleglvvlnipsyagGadlwg 93 vmnNYfs+G+DA+++leFhe+Re++P +fn+r++n l+Y+k + +++ +++ + + ++ +l++dg ++ +l+ +k+ +l+++ni+sy++G+++wg FUN_001529-T1 233 VMNNYFSLGFDAEVCLEFHESREANPDKFNNRIKNLLFYGKASSTTFRQRKAHYIFKHSTLQCDGVDLteKLQeTKPLCLLFVNISSYSAGTSPWG 328 7****************************************99999889999999*************8878878999****************** PP DAGK_acc 94 eskeekekfekqsvdDgllEvvglegvlhlgqvqvglkkakrlaqaseikietkkklpvqvDGep 158 + +++e f+ q+ dDg+lEv+gl+ + +l++++vg + + r+aq++e + t+k+lp+qvDGep FUN_001529-T1 329 HPGKDSE-FQLQRQDDGYLEVIGLT-TGTLATTRVGGHGE-RIAQCKEAVLVTRKTLPMQVDGEP 390 ****886.*****************.99**********99.***********************7 PP >> DAGK_cat Diacylglycerol kinase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 97.1 0.0 2.7e-31 7.6e-28 1 113 [. 63 173 .. 63 184 .. 0.91 Alignments for each domain: == domain 1 score: 97.1 bits; conditional E-value: 2.7e-31 DAGK_cat 1 kllvivNpksGkgkgkkllkkveellekagvelelveteeagdakelareaaekgvdlvvvvGGDGtvnevlnglae..latkpplgiiPlGtgNd 94 +llv++NpksG+++g+++l+k++ ll++++v ++l + ++ + el r++++ +++++GGDGtv++vl+ l++ + +pp++++PlGtgNd FUN_001529-T1 63 PLLVFINPKSGGNQGARILRKFQWLLNPRQV-FDLSDG-GPRLGLELYRKVPN---LRILACGGDGTVGWVLSELDKlkVSPPPPVAVLPLGTGND 153 589****************************.****98.58889*********...9********************999999************* PP DAGK_cat 95 faralglpk.dpeealeall 113 ++r+l++++ +e l+++l FUN_001529-T1 154 LSRVLNWGGgYTDEPLSRIL 173 ********987777777774 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 0.0 2.3e-09 6.6e-06 33 81 .. 643 693 .. 627 701 .. 0.70 2 ! 51.7 0.0 4.8e-17 1.4e-13 2 90 .] 644 738 .. 643 738 .. 0.88 3 ! 26.8 0.0 2.9e-09 8.3e-06 26 79 .. 705 760 .. 696 770 .. 0.86 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 2.3e-09 Ank_2 33 LhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 ++ A kng l+ v L +g ++ d g+ +LhyA+++gh+eiv+++++ FUN_001529-T1 643 MIEASKNGVLDKVIELHRNGTSLSagDHRGWRPLHYASRHGHKEIVRYIIS 693 666777777777777777764444556778888888887788888877774 PP == domain 2 score: 51.7 bits; conditional E-value: 4.8e-17 Ank_2 2 mlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehg..advn...dnngrtaLhyAaesghleivklLlekgadinakd 90 + A+kng l+ v +L+ +g++ d +g+ +Lh+A ++gh+eiv++ +++ + ++ ++ g+taLh Aa + + i+ lL++ ga+++++d FUN_001529-T1 644 IEASKNGVLDKVIELHrNGTSLSAGDHRGWRPLHYASRHGHKEIVRYIISNVprCVLDlveEERGQTALHKAAIYERRTICSLLVQAGASLTRTD 738 568899*99999999999999998899**********************974333355666788*********************99**999887 PP == domain 3 score: 26.8 bits; conditional E-value: 2.9e-09 Ank_2 26 dkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklL 79 +++g+taLh Aa + + i++lL++ ga++ d +g+t+ + A + + +e +k+L FUN_001529-T1 705 EERGQTALHKAAIYERRTICSLLVQAGASLTrtDYDGNTPRIQALKAQDKELAKYL 760 3389***********99********998766688*********************9 PP >> DGKI Diacylglycerol kinase iota-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.3 0.3 6.1e-26 1.7e-22 3 111 .] 432 533 .. 430 533 .. 0.94 Alignments for each domain: == domain 1 score: 80.3 bits; conditional E-value: 6.1e-26 DGKI 3 lriqvkkislkdYeklhydkdklkeasielGiisvesdadleevRklieklledsekeekeesksakklskdWcFvDsttaerffRidraqEhlhy 98 +++q+ + +k+Yek+ yd ++l+ +s + + ++e+d+dle++R+ i +++ed e+ +++ ls+dWcF+D+t +r++R+d aqE+++ FUN_001529-T1 432 VKLQIVCVGFKEYEKHCYDLSQLRLTSRLIATTTIEPDCDLEQMRAWIARFRED-------EEDEKTPLSDDWCFLDTTYPDRVYRVDLAQEKIYN 520 799************************************************976.......3345789**************************** PP DGKI 99 vtdissdelyild 111 v+di +d ++i+d FUN_001529-T1 521 VVDILEDGIFIVD 533 ***********98 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 1.9e-07 0.00053 7 50 .] 649 692 .. 643 692 .. 0.80 2 ! 7.1 0.0 0.0036 10 28 49 .. 706 727 .. 700 728 .. 0.84 3 ! 21.1 0.0 1.5e-07 0.00042 1 49 [. 712 760 .. 712 761 .. 0.98 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 1.9e-07 Ank_4 7 sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 g l+ + L+ ng ++ a d+ g+ +Lh+A+++g+ e++++ + FUN_001529-T1 649 NGVLDKVIELHRNGTSLSAGDHRGWRPLHYASRHGHKEIVRYII 692 55566666677788887888999*****************9965 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0036 Ank_4 28 gngetaLhfAasngnlevlklL 49 + g+taLh+Aa ++ +++lL FUN_001529-T1 706 ERGQTALHKAAIYERRTICSLL 727 679*********9999999888 PP == domain 3 score: 21.1 bits; conditional E-value: 1.5e-07 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+Aa++++ ++ lL++ ga++ +td++g+t+ A++ + e +k+L FUN_001529-T1 712 LHKAAIYERRTICSLLVQAGASLTRTDYDGNTPRIQALKAQDKELAKYL 760 8***********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 1.6e-07 0.00046 2 25 .. 672 694 .. 671 701 .. 0.87 2 ! 17.6 0.0 1.8e-06 0.005 2 32 .. 708 738 .. 707 739 .. 0.90 3 ? 1.3 0.0 0.28 7.8e+02 1 21 [. 740 760 .. 740 763 .. 0.94 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1.6e-07 Ank 2 GnTPLHlAaraghlevvklLLkhG 25 G+ PLH+A+r+gh e+v+++++ + FUN_001529-T1 672 GWRPLHYASRHGHKEIVRYIIS-N 694 899*****************94.4 PP == domain 2 score: 17.6 bits; conditional E-value: 1.8e-06 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH Aa + + ++ lL+++GA++ +d FUN_001529-T1 708 GQTALHKAAIYERRTICSLLVQAGASLTRTD 738 9*****999899999******98***98877 PP == domain 3 score: 1.3 bits; conditional E-value: 0.28 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP A +a + e++k+L FUN_001529-T1 740 DGNTPRIQALKAQDKELAKYL 760 7*********99******998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 4e-07 0.0011 2 23 .. 672 693 .. 671 697 .. 0.92 2 ! 15.0 0.0 1.3e-05 0.038 2 29 .. 708 734 .. 707 736 .. 0.92 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 4e-07 Ank_3 2 gntpLhlAarngrleivklLle 23 g+ pLh+A r+g+ eiv++++ FUN_001529-T1 672 GWRPLHYASRHGHKEIVRYIIS 693 99******************98 PP == domain 2 score: 15.0 bits; conditional E-value: 1.3e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g+t+Lh Aa++ r +i+ lL++ ga++ FUN_001529-T1 708 GQTALHKAAIYERRTICSLLVQ-AGASL 734 9********************9.88876 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.0 1.3e-08 3.7e-05 1 56 [] 658 715 .. 658 715 .. 0.94 2 ! 12.2 0.0 9.6e-05 0.27 12 53 .. 704 745 .. 699 748 .. 0.92 3 ? 2.1 0.0 0.14 4e+02 1 35 [. 727 760 .. 726 760 .. 0.86 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.3e-08 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLl..angvdlnlkdeeg.ltpldlA 56 L+ ng +++ + +g+ pLh+A+++g+ eivr+++ +++ l l +ee +t+l+ A FUN_001529-T1 658 LHRNGtSLSAGDHRGW--RPLHYASRHGHKEIVRYIIsnVPRCVLDLVEEERgQTALHKA 715 7899999999999999..*******************************9999****976 PP == domain 2 score: 12.2 bits; conditional E-value: 9.6e-05 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++++g+t+Lh+Aa y + +i lL+ g++l+ +d +g+tp FUN_001529-T1 704 EEERGQTALHKAAIYERRTICSLLVQAGASLTRTDYDGNTPR 745 788999*********************************996 PP == domain 3 score: 2.1 bits; conditional E-value: 0.14 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlL 35 L+++g a+l r+d +g+tp + A k+ e++++L FUN_001529-T1 727 LVQAG-ASLTRTDYDGNTPRIQALKAQDKELAKYL 760 78999.9************9999988877777765 PP >> MOV-10_beta-barrel Helicase MOV-10, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 2.3e-05 0.064 20 46 .. 559 585 .. 548 593 .. 0.82 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 2.3e-05 MOV-10_beta-barrel 20 leVpGlAenrPSvlrGDkilvklsedk 46 l+VpG A rPSvl+G++ +v+l + + FUN_001529-T1 559 LSVPGYAFSRPSVLNGNRTVVTLPSPT 585 89*****************99976433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (778 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 686 (0.0268546); expected 510.9 (0.02) Passed bias filter: 590 (0.0230965); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 7579.13 // Query: FUN_001529-T2 [L=938] Description: FUN_001529 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-42 146.4 0.0 2.3e-42 145.5 0.0 1.5 1 DAGK_acc Diacylglycerol kinase accessory domain 5e-28 97.7 0.0 1e-27 96.7 0.0 1.5 1 DAGK_cat Diacylglycerol kinase catalytic domain 9.4e-26 90.7 0.0 1.8e-13 51.4 0.0 2.5 3 Ank_2 Ankyrin repeats (3 copies) 2.2e-22 79.9 0.3 2.2e-22 79.9 0.3 2.3 2 DGKI Diacylglycerol kinase iota-like domain 8.8e-12 45.4 0.1 0.00053 20.7 0.0 3.6 4 Ank_4 Ankyrin repeats (many copies) 2.8e-11 43.5 0.0 0.00057 20.6 0.0 3.6 3 Ank Ankyrin repeat 2e-09 37.3 0.0 0.0014 19.4 0.0 3.0 2 Ank_3 Ankyrin repeat 8.3e-08 32.4 26.5 7.9e-06 26.1 13.8 2.5 2 C1_1 Phorbol esters/diacylglycerol binding dom 2.9e-07 31.2 0.0 4.7e-05 24.2 0.0 2.7 2 Ank_5 Ankyrin repeats (many copies) ------ inclusion threshold ------ 0.022 14.7 0.0 0.08 12.9 0.0 1.9 1 MOV-10_beta-barrel Helicase MOV-10, beta-barrel domain 0.032 14.6 1.1 15 6.1 0.1 2.9 2 ADK_lid Adenylate kinase, active site lid 0.074 13.7 1.0 0.22 12.2 1.0 1.8 1 Zn_ribbon_13 Nucleic-acid-binding protein containing Z Domain annotation for each model (and alignments): >> DAGK_acc Diacylglycerol kinase accessory domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.5 0.0 1.1e-45 2.3e-42 1 158 [] 393 550 .. 393 550 .. 0.96 Alignments for each domain: == domain 1 score: 145.5 bits; conditional E-value: 1.1e-45 DAGK_acc 1 vmnNYfsiGvDAkialeFheaReekPelfnsrlvnKliYlklglkkllkkslknlkekvelevdgkev..elp.kkleglvvlnipsyagGadlwg 93 vmnNYfs+G+DA+++leFhe+Re++P +fn+r++n l+Y+k + +++ +++ + + ++ +l++dg ++ +l+ +k+ +l+++ni+sy++G+++wg FUN_001529-T2 393 VMNNYFSLGFDAEVCLEFHESREANPDKFNNRIKNLLFYGKASSTTFRQRKAHYIFKHSTLQCDGVDLteKLQeTKPLCLLFVNISSYSAGTSPWG 488 7****************************************99999889999999*************8878878999****************** PP DAGK_acc 94 eskeekekfekqsvdDgllEvvglegvlhlgqvqvglkkakrlaqaseikietkkklpvqvDGep 158 + +++e f+ q+ dDg+lEv+gl+ + +l++++vg + + r+aq++e + t+k+lp+qvDGep FUN_001529-T2 489 HPGKDSE-FQLQRQDDGYLEVIGLT-TGTLATTRVGGHGE-RIAQCKEAVLVTRKTLPMQVDGEP 550 ****886.*****************.99**********99.***********************7 PP >> DAGK_cat Diacylglycerol kinase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.7 0.0 4.7e-31 1e-27 1 113 [. 223 333 .. 223 344 .. 0.91 Alignments for each domain: == domain 1 score: 96.7 bits; conditional E-value: 4.7e-31 DAGK_cat 1 kllvivNpksGkgkgkkllkkveellekagvelelveteeagdakelareaaekgvdlvvvvGGDGtvnevlnglae..latkpplgiiPlGtgNd 94 +llv++NpksG+++g+++l+k++ ll++++v ++l + ++ + el r++++ +++++GGDGtv++vl+ l++ + +pp++++PlGtgNd FUN_001529-T2 223 PLLVFINPKSGGNQGARILRKFQWLLNPRQV-FDLSDG-GPRLGLELYRKVPN---LRILACGGDGTVGWVLSELDKlkVSPPPPVAVLPLGTGND 313 589****************************.****98.58889*********...9********************999999************* PP DAGK_cat 95 faralglpk.dpeealeall 113 ++r+l++++ +e l+++l FUN_001529-T2 314 LSRVLNWGGgYTDEPLSRIL 333 ********987777777774 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 3.9e-09 8.2e-06 33 81 .. 803 853 .. 787 862 .. 0.70 2 ! 51.4 0.0 8.2e-17 1.8e-13 2 90 .] 804 898 .. 803 898 .. 0.88 3 ! 26.5 0.0 4.7e-09 9.9e-06 26 79 .. 865 920 .. 854 929 .. 0.86 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 3.9e-09 Ank_2 33 LhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 ++ A kng l+ v L +g ++ d g+ +LhyA+++gh+eiv+++++ FUN_001529-T2 803 MIEASKNGVLDKVIELHRNGTSLSagDHRGWRPLHYASRHGHKEIVRYIIS 853 666777777777777777764444556777788888877777777777774 PP == domain 2 score: 51.4 bits; conditional E-value: 8.2e-17 Ank_2 2 mlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehg..advn...dnngrtaLhyAaesghleivklLlekgadinakd 90 + A+kng l+ v +L+ +g++ d +g+ +Lh+A ++gh+eiv++ +++ + ++ ++ g+taLh Aa + + i+ lL++ ga+++++d FUN_001529-T2 804 IEASKNGVLDKVIELHrNGTSLSAGDHRGWRPLHYASRHGHKEIVRYIISNVprCVLDlveEERGQTALHKAAIYERRTICSLLVQAGASLTRTD 898 568899*99999999999999998899**********************974333355666788*********************99**999887 PP == domain 3 score: 26.5 bits; conditional E-value: 4.7e-09 Ank_2 26 dkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklL 79 +++g+taLh Aa + + i++lL++ ga++ d +g+t+ + A + + +e +k+L FUN_001529-T2 865 EERGQTALHKAAIYERRTICSLLVQAGASLTrtDYDGNTPRIQALKAQDKELAKYL 920 2389***********99********998766688*********************9 PP >> DGKI Diacylglycerol kinase iota-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.3 0.74 1.6e+03 65 95 .. 131 161 .. 97 164 .. 0.75 2 ! 79.9 0.3 1.1e-25 2.2e-22 3 111 .] 592 693 .. 590 693 .. 0.94 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.74 DGKI 65 sksakklskdWcFvDsttaerffRidraqEh 95 +k+ +s +Wc ++e fR+ + E FUN_001529-T2 131 NKDFIAISCSWCKAAYHNKEECFRLSKIEEM 161 367778999***************9998875 PP == domain 2 score: 79.9 bits; conditional E-value: 1.1e-25 DGKI 3 lriqvkkislkdYeklhydkdklkeasielGiisvesdadleevRklieklledsekeekeesksakklskdWcFvDsttaerffRidraqEhlhy 98 +++q+ + +k+Yek+ yd ++l+ +s + + ++e+d+dle++R+ i +++ed e+ +++ ls+dWcF+D+t +r++R+d aqE+++ FUN_001529-T2 592 VKLQIVCVGFKEYEKHCYDLSQLRLTSRLIATTTIEPDCDLEQMRAWIARFRED-------EEDEKTPLSDDWCFLDTTYPDRVYRVDLAQEKIYN 680 799************************************************976.......3345789**************************** PP DGKI 99 vtdissdelyild 111 v+di +d ++i+d FUN_001529-T2 681 VVDILEDGIFIVD 693 ***********98 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2.3 4.9e+03 3 15 .. 143 155 .. 142 158 .. 0.82 2 ! 20.4 0.0 3.1e-07 0.00067 7 50 .] 809 852 .. 803 852 .. 0.80 3 ! 6.8 0.0 0.0059 13 28 49 .. 866 887 .. 860 888 .. 0.84 4 ! 20.7 0.0 2.5e-07 0.00053 1 49 [. 872 920 .. 872 921 .. 0.98 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.3 Ank_4 3 aAaksghlellkl 15 +Aa+++++e+ +l FUN_001529-T2 143 KAAYHNKEECFRL 155 7999999999875 PP == domain 2 score: 20.4 bits; conditional E-value: 3.1e-07 Ank_4 7 sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 g l+ + L+ ng ++ a d+ g+ +Lh+A+++g+ e++++ + FUN_001529-T2 809 NGVLDKVIELHRNGTSLSAGDHRGWRPLHYASRHGHKEIVRYII 852 55566666677788887788999*****************9965 PP == domain 3 score: 6.8 bits; conditional E-value: 0.0059 Ank_4 28 gngetaLhfAasngnlevlklL 49 + g+taLh+Aa ++ +++lL FUN_001529-T2 866 ERGQTALHKAAIYERRTICSLL 887 679*********9999999888 PP == domain 4 score: 20.7 bits; conditional E-value: 2.5e-07 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+Aa++++ ++ lL++ ga++ +td++g+t+ A++ + e +k+L FUN_001529-T2 872 LHKAAIYERRTICSLLVQAGASLTRTDYDGNTPRIQALKAQDKELAKYL 920 8***********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 2.7e-07 0.00057 2 25 .. 832 854 .. 831 861 .. 0.87 2 ! 17.3 0.0 2.9e-06 0.0063 2 32 .. 868 898 .. 867 899 .. 0.90 3 ? 0.9 0.0 0.47 1e+03 1 21 [. 900 920 .. 900 922 .. 0.94 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 2.7e-07 Ank 2 GnTPLHlAaraghlevvklLLkhG 25 G+ PLH+A+r+gh e+v+++++ + FUN_001529-T2 832 GWRPLHYASRHGHKEIVRYIIS-N 854 899*****************94.4 PP == domain 2 score: 17.3 bits; conditional E-value: 2.9e-06 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH Aa + + ++ lL+++GA++ +d FUN_001529-T2 868 GQTALHKAAIYERRTICSLLVQAGASLTRTD 898 9*****999899999******98**998877 PP == domain 3 score: 0.9 bits; conditional E-value: 0.47 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP A +a + e++k+L FUN_001529-T2 900 DGNTPRIQALKAQDKELAKYL 920 7*********99******998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 6.6e-07 0.0014 2 23 .. 832 853 .. 831 857 .. 0.92 2 ! 14.7 0.0 2.2e-05 0.048 2 29 .. 868 894 .. 867 896 .. 0.92 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 6.6e-07 Ank_3 2 gntpLhlAarngrleivklLle 23 g+ pLh+A r+g+ eiv++++ FUN_001529-T2 832 GWRPLHYASRHGHKEIVRYIIS 853 99******************98 PP == domain 2 score: 14.7 bits; conditional E-value: 2.2e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g+t+Lh Aa++ r +i+ lL++ ga++ FUN_001529-T2 868 GQTALHKAAIYERRTICSLLVQ-AGASL 894 9********************9.88876 PP >> C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 4.7 0.00012 0.25 1 47 [. 35 79 .. 35 86 .. 0.76 2 ! 26.1 13.8 3.7e-09 7.9e-06 1 52 [. 104 162 .. 104 163 .. 0.90 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00012 C1_1 1 HhfvarnfkqptfCd..hCgellwglakqglkCswCklnvHkkClekvp 47 H + +++ + ++C +C++l ++ + kC++Ck+ H kC+ +++ FUN_001529-T2 35 HVWIDTD-ISGNSCYltECESL---KSGPRKKCAACKIILHAKCIDQLH 79 7777777.77777751145554...59999**************98764 PP == domain 2 score: 26.1 bits; conditional E-value: 3.7e-09 C1_1 1 HhfvarnfkqptfCdhCgell.....wg.lakqglkCswCklnvHkk..Clekvppecgl 52 Hh+v+r+ kq+++C +Cg+++ ++ + + +++CswCk +H+k C+++ + e+ + FUN_001529-T2 104 HHWVHRR-KQEGKCHKCGKSFqhklsFQnKDFIAISCSWCKAAYHNKeeCFRLSKIEEMC 162 *******.*************9998844588999*************9***998887766 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 2.2e-08 4.7e-05 1 56 [] 818 875 .. 818 875 .. 0.94 2 ! 11.9 0.0 0.00016 0.34 12 53 .. 864 905 .. 859 908 .. 0.92 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 2.2e-08 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLl..angvdlnlkdeeg.ltpldlA 56 L+ ng +++ + +g+ pLh+A+++g+ eivr+++ +++ l l +ee +t+l+ A FUN_001529-T2 818 LHRNGtSLSAGDHRGW--RPLHYASRHGHKEIVRYIIsnVPRCVLDLVEEERgQTALHKA 875 7899999999999999..*******************************9999****976 PP == domain 2 score: 11.9 bits; conditional E-value: 0.00016 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++++g+t+Lh+Aa y + +i lL+ g++l+ +d +g+tp FUN_001529-T2 864 EEERGQTALHKAAIYERRTICSLLVQAGASLTRTDYDGNTPR 905 788999*********************************996 PP >> MOV-10_beta-barrel Helicase MOV-10, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 3.7e-05 0.08 20 46 .. 719 745 .. 708 753 .. 0.82 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 3.7e-05 MOV-10_beta-barrel 20 leVpGlAenrPSvlrGDkilvklsedk 46 l+VpG A rPSvl+G++ +v+l + + FUN_001529-T2 719 LSVPGYAFSRPSVLNGNRTVVTLPSPT 745 89*****************99976433 PP >> ADK_lid Adenylate kinase, active site lid # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.1 0.0069 15 19 30 .. 111 122 .. 101 125 .. 0.83 2 ? 6.0 0.2 0.0071 15 3 25 .. 138 163 .. 137 165 .. 0.84 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0069 ADK_lid 19 kvegvCDvcGee 30 k+eg+C +cG FUN_001529-T2 111 KQEGKCHKCGKS 122 99********75 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0071 ADK_lid 3 vCpkCGrvYhlv...fnpPkvegvCD 25 C+ C++ Yh + f+ +k e CD FUN_001529-T2 138 SCSWCKAAYHNKeecFRLSKIEEMCD 163 699*******7765558899999999 PP >> Zn_ribbon_13 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 1.0 0.0001 0.22 11 42 .. 112 143 .. 107 159 .. 0.87 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0001 Zn_ribbon_13 11 evkeiaatGgglsklfdvqnkkfivvsCknCg 42 ++++ + +G + + qnk fi++sC+ C+ FUN_001529-T2 112 QEGKCHKCGKSFQHKLSFQNKDFIAISCSWCK 143 5677889999*********************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (938 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 913 (0.0357408); expected 510.9 (0.02) Passed bias filter: 574 (0.0224702); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.41u 0.41s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 8965.64 // Query: FUN_001529-T3 [L=996] Description: FUN_001529 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-42 146.2 0.0 2.5e-42 145.4 0.0 1.5 1 DAGK_acc Diacylglycerol kinase accessory domain 5.3e-28 97.6 0.0 1.1e-27 96.6 0.0 1.5 1 DAGK_cat Diacylglycerol kinase catalytic domain 1.3e-25 90.2 0.0 1.9e-13 51.3 0.0 2.5 3 Ank_2 Ankyrin repeats (3 copies) 2.4e-22 79.8 0.3 2.4e-22 79.8 0.3 2.3 2 DGKI Diacylglycerol kinase iota-like domain 1.1e-11 45.1 0.2 0.00057 20.6 0.0 3.5 3 Ank_4 Ankyrin repeats (many copies) 3.4e-11 43.2 0.0 0.00061 20.5 0.0 3.6 3 Ank Ankyrin repeat 2.4e-09 37.1 0.0 0.0015 19.3 0.0 3.0 2 Ank_3 Ankyrin repeat 9.7e-08 32.2 26.5 8.5e-06 26.0 13.8 2.5 2 C1_1 Phorbol esters/diacylglycerol binding dom 3.3e-07 31.0 0.0 5e-05 24.1 0.0 2.7 2 Ank_5 Ankyrin repeats (many copies) ------ inclusion threshold ------ 0.024 14.6 0.0 0.085 12.8 0.0 1.9 1 MOV-10_beta-barrel Helicase MOV-10, beta-barrel domain 0.035 14.5 1.1 16 6.0 0.1 2.9 2 ADK_lid Adenylate kinase, active site lid 0.081 13.6 1.0 0.23 12.1 1.0 1.8 1 Zn_ribbon_13 Nucleic-acid-binding protein containing Z Domain annotation for each model (and alignments): >> DAGK_acc Diacylglycerol kinase accessory domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.4 0.0 1.2e-45 2.5e-42 1 158 [] 451 608 .. 451 608 .. 0.96 Alignments for each domain: == domain 1 score: 145.4 bits; conditional E-value: 1.2e-45 DAGK_acc 1 vmnNYfsiGvDAkialeFheaReekPelfnsrlvnKliYlklglkkllkkslknlkekvelevdgkev..elp.kkleglvvlnipsyagGadlwg 93 vmnNYfs+G+DA+++leFhe+Re++P +fn+r++n l+Y+k + +++ +++ + + ++ +l++dg ++ +l+ +k+ +l+++ni+sy++G+++wg FUN_001529-T3 451 VMNNYFSLGFDAEVCLEFHESREANPDKFNNRIKNLLFYGKASSTTFRQRKAHYIFKHSTLQCDGVDLteKLQeTKPLCLLFVNISSYSAGTSPWG 546 7****************************************99999889999999*************8878878999****************** PP DAGK_acc 94 eskeekekfekqsvdDgllEvvglegvlhlgqvqvglkkakrlaqaseikietkkklpvqvDGep 158 + +++e f+ q+ dDg+lEv+gl+ + +l++++vg + + r+aq++e + t+k+lp+qvDGep FUN_001529-T3 547 HPGKDSE-FQLQRQDDGYLEVIGLT-TGTLATTRVGGHGE-RIAQCKEAVLVTRKTLPMQVDGEP 608 ****886.*****************.99**********99.***********************7 PP >> DAGK_cat Diacylglycerol kinase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.6 0.0 5.1e-31 1.1e-27 1 113 [. 281 391 .. 281 402 .. 0.91 Alignments for each domain: == domain 1 score: 96.6 bits; conditional E-value: 5.1e-31 DAGK_cat 1 kllvivNpksGkgkgkkllkkveellekagvelelveteeagdakelareaaekgvdlvvvvGGDGtvnevlnglae..latkpplgiiPlGtgNd 94 +llv++NpksG+++g+++l+k++ ll++++v ++l + ++ + el r++++ +++++GGDGtv++vl+ l++ + +pp++++PlGtgNd FUN_001529-T3 281 PLLVFINPKSGGNQGARILRKFQWLLNPRQV-FDLSDG-GPRLGLELYRKVPN---LRILACGGDGTVGWVLSELDKlkVSPPPPVAVLPLGTGND 371 589****************************.****98.58889*********...9********************999999************* PP DAGK_cat 95 faralglpk.dpeealeall 113 ++r+l++++ +e l+++l FUN_001529-T3 372 LSRVLNWGGgYTDEPLSRIL 391 ********987777777774 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.0 4.2e-09 8.8e-06 33 81 .. 861 911 .. 845 920 .. 0.70 2 ! 51.3 0.0 8.9e-17 1.9e-13 2 90 .] 862 956 .. 861 956 .. 0.88 3 ! 26.4 0.0 5e-09 1.1e-05 26 79 .. 923 978 .. 912 987 .. 0.86 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 4.2e-09 Ank_2 33 LhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLle 81 ++ A kng l+ v L +g ++ d g+ +LhyA+++gh+eiv+++++ FUN_001529-T3 861 MIEASKNGVLDKVIELHRNGTSLSagDHRGWRPLHYASRHGHKEIVRYIIS 911 666777777777777777764444556777778888877777777777774 PP == domain 2 score: 51.3 bits; conditional E-value: 8.9e-17 Ank_2 2 mlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehg..advn...dnngrtaLhyAaesghleivklLlekgadinakd 90 + A+kng l+ v +L+ +g++ d +g+ +Lh+A ++gh+eiv++ +++ + ++ ++ g+taLh Aa + + i+ lL++ ga+++++d FUN_001529-T3 862 IEASKNGVLDKVIELHrNGTSLSAGDHRGWRPLHYASRHGHKEIVRYIISNVprCVLDlveEERGQTALHKAAIYERRTICSLLVQAGASLTRTD 956 568899*99999999999999998899**********************974333355666788*********************99**999887 PP == domain 3 score: 26.4 bits; conditional E-value: 5e-09 Ank_2 26 dkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklL 79 +++g+taLh Aa + + i++lL++ ga++ d +g+t+ + A + + +e +k+L FUN_001529-T3 923 EERGQTALHKAAIYERRTICSLLVQAGASLTrtDYDGNTPRIQALKAQDKELAKYL 978 2389***********99********998766688*********************9 PP >> DGKI Diacylglycerol kinase iota-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.3 0.79 1.7e+03 65 95 .. 189 219 .. 155 222 .. 0.75 2 ! 79.8 0.3 1.1e-25 2.4e-22 3 111 .] 650 751 .. 648 751 .. 0.94 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.79 DGKI 65 sksakklskdWcFvDsttaerffRidraqEh 95 +k+ +s +Wc ++e fR+ + E FUN_001529-T3 189 NKDFIAISCSWCKAAYHNKEECFRLSKIEEM 219 367778999***************9998875 PP == domain 2 score: 79.8 bits; conditional E-value: 1.1e-25 DGKI 3 lriqvkkislkdYeklhydkdklkeasielGiisvesdadleevRklieklledsekeekeesksakklskdWcFvDsttaerffRidraqEhlhy 98 +++q+ + +k+Yek+ yd ++l+ +s + + ++e+d+dle++R+ i +++ed e+ +++ ls+dWcF+D+t +r++R+d aqE+++ FUN_001529-T3 650 VKLQIVCVGFKEYEKHCYDLSQLRLTSRLIATTTIEPDCDLEQMRAWIARFRED-------EEDEKTPLSDDWCFLDTTYPDRVYRVDLAQEKIYN 738 799************************************************976.......3345789**************************** PP DGKI 99 vtdissdelyild 111 v+di +d ++i+d FUN_001529-T3 739 VVDILEDGIFIVD 751 ***********98 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 2.5 5.4e+03 3 15 .. 201 213 .. 200 215 .. 0.81 2 ! 20.3 0.0 3.4e-07 0.00071 7 50 .] 867 910 .. 861 910 .. 0.80 3 ! 20.6 0.0 2.7e-07 0.00057 1 49 [. 930 978 .. 930 979 .. 0.98 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.5 Ank_4 3 aAaksghlellkl 15 +Aa+++++e+ +l FUN_001529-T3 201 KAAYHNKEECFRL 213 7999999999875 PP == domain 2 score: 20.3 bits; conditional E-value: 3.4e-07 Ank_4 7 sghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 g l+ + L+ ng ++ a d+ g+ +Lh+A+++g+ e++++ + FUN_001529-T3 867 NGVLDKVIELHRNGTSLSAGDHRGWRPLHYASRHGHKEIVRYII 910 55566666677788887788999*****************9965 PP == domain 3 score: 20.6 bits; conditional E-value: 2.7e-07 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+Aa++++ ++ lL++ ga++ +td++g+t+ A++ + e +k+L FUN_001529-T3 930 LHKAAIYERRTICSLLVQAGASLTRTDYDGNTPRIQALKAQDKELAKYL 978 8***********************************************9 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 2.8e-07 0.00061 2 25 .. 890 912 .. 889 919 .. 0.87 2 ! 17.2 0.0 3.2e-06 0.0067 2 32 .. 926 956 .. 925 957 .. 0.90 3 ? 0.9 0.0 0.5 1.1e+03 1 21 [. 958 978 .. 958 980 .. 0.94 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 2.8e-07 Ank 2 GnTPLHlAaraghlevvklLLkhG 25 G+ PLH+A+r+gh e+v+++++ + FUN_001529-T3 890 GWRPLHYASRHGHKEIVRYIIS-N 912 899*****************94.4 PP == domain 2 score: 17.2 bits; conditional E-value: 3.2e-06 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH Aa + + ++ lL+++GA++ +d FUN_001529-T3 926 GQTALHKAAIYERRTICSLLVQAGASLTRTD 956 9*****999899999******98**998877 PP == domain 3 score: 0.9 bits; conditional E-value: 0.5 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP A +a + e++k+L FUN_001529-T3 958 DGNTPRIQALKAQDKELAKYL 978 7*********99******998 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 7.1e-07 0.0015 2 23 .. 890 911 .. 889 915 .. 0.92 2 ! 14.6 0.0 2.4e-05 0.051 2 29 .. 926 952 .. 925 954 .. 0.92 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 7.1e-07 Ank_3 2 gntpLhlAarngrleivklLle 23 g+ pLh+A r+g+ eiv++++ FUN_001529-T3 890 GWRPLHYASRHGHKEIVRYIIS 911 99******************98 PP == domain 2 score: 14.6 bits; conditional E-value: 2.4e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadi 29 g+t+Lh Aa++ r +i+ lL++ ga++ FUN_001529-T3 926 GQTALHKAAIYERRTICSLLVQ-AGASL 952 9********************9.88876 PP >> C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.6 4.7 0.00012 0.26 1 47 [. 93 137 .. 93 144 .. 0.76 2 ! 26.0 13.8 4e-09 8.5e-06 1 52 [. 162 220 .. 162 221 .. 0.90 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00012 C1_1 1 HhfvarnfkqptfCd..hCgellwglakqglkCswCklnvHkkClekvp 47 H + +++ + ++C +C++l ++ + kC++Ck+ H kC+ +++ FUN_001529-T3 93 HVWIDTD-ISGNSCYltECESL---KSGPRKKCAACKIILHAKCIDQLH 137 7777777.77777751145554...59999**************98764 PP == domain 2 score: 26.0 bits; conditional E-value: 4e-09 C1_1 1 HhfvarnfkqptfCdhCgell.....wg.lakqglkCswCklnvHkk..Clekvppecgl 52 Hh+v+r+ kq+++C +Cg+++ ++ + + +++CswCk +H+k C+++ + e+ + FUN_001529-T3 162 HHWVHRR-KQEGKCHKCGKSFqhklsFQnKDFIAISCSWCKAAYHNKeeCFRLSKIEEMC 220 *******.*************9998844588999*************9***998887766 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 2.4e-08 5e-05 1 56 [] 876 933 .. 876 933 .. 0.94 2 ! 11.8 0.0 0.00017 0.37 12 53 .. 922 963 .. 917 966 .. 0.92 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 2.4e-08 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLl..angvdlnlkdeeg.ltpldlA 56 L+ ng +++ + +g+ pLh+A+++g+ eivr+++ +++ l l +ee +t+l+ A FUN_001529-T3 876 LHRNGtSLSAGDHRGW--RPLHYASRHGHKEIVRYIIsnVPRCVLDLVEEERgQTALHKA 933 7899999999999999..*******************************9999****976 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00017 Ank_5 12 ldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 ++++g+t+Lh+Aa y + +i lL+ g++l+ +d +g+tp FUN_001529-T3 922 EEERGQTALHKAAIYERRTICSLLVQAGASLTRTDYDGNTPR 963 788999*********************************996 PP >> MOV-10_beta-barrel Helicase MOV-10, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 4e-05 0.085 20 46 .. 777 803 .. 766 811 .. 0.82 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 4e-05 MOV-10_beta-barrel 20 leVpGlAenrPSvlrGDkilvklsedk 46 l+VpG A rPSvl+G++ +v+l + + FUN_001529-T3 777 LSVPGYAFSRPSVLNGNRTVVTLPSPT 803 89*****************99976433 PP >> ADK_lid Adenylate kinase, active site lid # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.1 0.0073 16 19 30 .. 169 180 .. 159 183 .. 0.83 2 ? 6.0 0.2 0.0075 16 3 25 .. 196 221 .. 195 223 .. 0.84 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0073 ADK_lid 19 kvegvCDvcGee 30 k+eg+C +cG FUN_001529-T3 169 KQEGKCHKCGKS 180 99********75 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0075 ADK_lid 3 vCpkCGrvYhlv...fnpPkvegvCD 25 C+ C++ Yh + f+ +k e CD FUN_001529-T3 196 SCSWCKAAYHNKeecFRLSKIEEMCD 221 699*******7765558899999999 PP >> Zn_ribbon_13 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 1.0 0.00011 0.23 11 42 .. 170 201 .. 165 217 .. 0.87 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00011 Zn_ribbon_13 11 evkeiaatGgglsklfdvqnkkfivvsCknCg 42 ++++ + +G + + qnk fi++sC+ C+ FUN_001529-T3 170 QEGKCHKCGKSFQHKLSFQNKDFIAISCSWCK 201 5677889999*********************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (996 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1003 (0.039264); expected 510.9 (0.02) Passed bias filter: 619 (0.0242317); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.41 # Mc/sec: 9853.08 // Query: FUN_001530-T1 [L=451] Description: FUN_001530 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-174 580.5 0.0 1.5e-174 580.1 0.0 1.1 1 Biopterin_H Biopterin-dependent aromatic amino acid hydroxyl 5.3e-07 29.8 0.0 1.1e-06 28.8 0.0 1.6 1 ACT ACT domain 4.3e-06 27.0 0.2 7.5e-06 26.2 0.2 1.4 1 TH_ACT Tyrosine 3-monooxygenase-like, ACT domain Domain annotation for each model (and alignments): >> Biopterin_H Biopterin-dependent aromatic amino acid hydroxylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 580.1 0.0 1.8e-178 1.5e-174 1 330 [. 118 447 .. 118 448 .. 1.00 Alignments for each domain: == domain 1 score: 580.1 bits; conditional E-value: 1.8e-178 Biopterin_H 1 pWfPrkisdlDkcakkvlkygaeldadhPGfkdkvyrkrrkeiadialnykhgepiprveyteeeiktWkevykklkelypthaCkeyleafklle 96 pWfPrki+dlDk+a++vl+ygaeld+dhPGf+d+vyr+rrk++adia+n+khgepip+v yte+eiktW++v+++l++lyp+haC+e++++++ll FUN_001530-T1 118 PWFPRKIADLDKFANRVLSYGAELDSDHPGFTDPVYRARRKQFADIAFNHKHGEPIPTVTYTEDEIKTWNKVFSELTKLYPSHACREHNYVWPLLV 213 7*********************************************************************************************** PP Biopterin_H 97 kecgykedniPqledvskfLkektGfklrpvagllsarDfLaglafrvfqstqyirhsskPlytpePDvvhellGhvplladkefaqfsqeiglas 192 ++cgy+ dniPq e vskfLke++Gf+lrpvaglls+rDfLaglafrvf++tqyirh s+P+ytpePD+vhel+Ghvpl+ad++faqfsqeiglas FUN_001530-T1 214 QNCGYRLDNIPQQEVVSKFLKECSGFSLRPVAGLLSSRDFLAGLAFRVFHATQYIRHGSTPMYTPEPDIVHELIGHVPLFADPDFAQFSQEIGLAS 309 ************************************************************************************************ PP Biopterin_H 193 lGasdeeieklatlywftvefglckqngelkaygagllssfgelkyalsdkpevkpfdpevtavqkyeiteyqpvyfvaesfedakeklrkfaktl 288 lGa+de i+klatlywftvefglck+ng++kaygagllssfgel+y+l+++pe++pf+pe+ta q+y+it+yqp+yfva+sf++akek+r+fa+++ FUN_001530-T1 310 LGAPDEWIDKLATLYWFTVEFGLCKENGDVKAYGAGLLSSFGELQYCLTEEPEKRPFEPEKTAAQTYPITKYQPIYFVADSFQSAKEKVREFAARI 405 ************************************************************************************************ PP Biopterin_H 289 krpfsvrydpytqsvevldskeklkkllkelkeelklltkal 330 rpfsvry+pytqsvevldsk+++ kl+++++ ++++l++al FUN_001530-T1 406 PRPFSVRYNPYTQSVEVLDSKDQILKLANDIRADVSTLQDAL 447 ***************************************998 PP >> ACT ACT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 0.0 1.3e-10 1.1e-06 2 57 .. 35 90 .. 34 99 .. 0.82 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 1.3e-10 ACT 2 vlevlvpDrpGlLarvlgalaergiNitsieqgtsedkggivfvvivvdeedleev 57 ++ ++++ ++G Lar l+++ ++ +N +ie+++s+++ +++++ ++ +e + +++ FUN_001530-T1 35 SIVFSLKEEVGSLARALKLFEDHKVNMSHIESRPSRRSKSEYDFYVDCEELQGPKL 90 68899********************************9666666666666555555 PP >> TH_ACT Tyrosine 3-monooxygenase-like, ACT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.2 8.8e-10 7.5e-06 3 57 .. 33 83 .. 31 97 .. 0.82 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 8.8e-10 TH_ACT 3 vlnLlFtLksvkksslSkavkvFEtFEakiHHlEtRrakkpknsaedLevFvrce 57 ++++F+Lk++ sl +a+k FE + H+E+R+++++k ++ +++v ce FUN_001530-T1 33 HISIVFSLKEE-VGSLARALKLFEDHKVNMSHIESRPSRRSK---SEYDFYVDCE 83 57889999976.578**********************99986...6889*****8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (451 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 609 (0.0238403); expected 510.9 (0.02) Passed bias filter: 569 (0.0222744); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.45s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 4501.82 // Query: FUN_001531-T1 [L=1363] Description: FUN_001531 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-53 181.6 6.6 3.8e-53 180.5 6.6 1.6 1 DENN DENN (AEX-3) domain 3.3e-33 115.1 5.6 5.7e-16 59.3 0.0 3.2 3 RUN RUN domain 1.3e-17 64.5 0.1 1.1e-16 61.6 0.0 2.7 2 uDENN uDENN domain 4.1e-13 50.6 0.1 1.2e-12 49.1 0.1 1.9 1 PLAT PLAT/LH2 domain 1.2e-12 48.2 2.4 3.9e-12 46.5 2.4 2.0 1 dDENN dDENN domain Domain annotation for each model (and alignments): >> DENN DENN (AEX-3) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 180.5 6.6 7.5e-57 3.8e-53 2 185 .. 188 374 .. 187 375 .. 0.97 Alignments for each domain: == domain 1 score: 180.5 bits; conditional E-value: 7.5e-57 DENN 2 vpkaiciisrlpffeafkkiLealekrvesssk.elplesfianllaevplPapgktlklkslsvkekillqrpedselPledvdlkellklLsve 96 v+k+icii++lpf++a k +Le+++ +v+++++ +lples+i+nll evplP++gkt+++ ++++ +i++qrp+++e+Pl d++ kel++lL+ve FUN_001531-T1 188 VSKSICIIMPLPFISAGKAFLEQIYCSVQKEDDlPLPLESYIYNLLFEVPLPPSGKTMRF--SCNDLNITCQRPSSNEIPLFDYSSKELFSLLGVE 281 689**********************999999888**************************..89******************************** PP DENN 97 nvlqllalvLlErrilllSsdlslLssvaealvalLfPlkWqhiyiPvlPasLldvlsaPvpflvGvesslle....leeepledvvlvdldk 185 n+++l+++ LlE++ill+S+d++ ++ vae+++a++fP+ Wqh+y+P+lP +L ++l+aPvpfl+G+ ++++e l +++ ++lvd+d+ FUN_001531-T1 282 NIVKLFTCCLLEQQILLISNDFHKFMLVAESMSAIIFPFIWQHVYVPILPPALSHFLDAPVPFLMGIYCASEEekknLVLPSEASLCLVDIDN 374 *******************************************************************9999887788888999*********8 PP >> RUN RUN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.1 0.72 3.7e+03 32 60 .. 781 809 .. 687 824 .. 0.49 2 ! 56.8 0.6 6.7e-19 3.4e-15 1 125 [. 855 1022 .. 855 1026 .. 0.89 3 ! 59.3 0.0 1.1e-19 5.7e-16 2 129 .. 1220 1356 .. 1219 1358 .. 0.90 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.72 RUN 32 sllerveklvpeaeellssvqeleqikss 60 +l ++++k+++e++ s++ ++e ++++ FUN_001531-T1 781 KLASSIKKYMQESKAKSSQFGDMELTHTA 809 22333355555555555555555555554 PP == domain 2 score: 56.8 bits; conditional E-value: 6.7e-19 RUN 1 eLcaalealLshGLkrssl.........................................raaglkkeksfwsllerveklvpeaeel...... 47 +Lc le + shGL+ + + + +++++++++++ ++++++ + FUN_001531-T1 855 SLCDLLERIWSHGLQTKEGksalwshllafqlefegtedlvsvqsqdsnslspmtgdnqsPLRRRCASPDIANMMQSI-QVSQQQPTIasvlad 947 59*************97669***********************************99886577777788888888888.444444444455677 PP RUN 48 lssvqeleqiksskspdgkgrawirlaLneklLeeylelllsnkellskyYepeAlladeefaeillslLvgLsaldf 125 +s vq++++i+++ g+ rawirlaL +k+L+++l+ ls+ +ll++ Y++ A+l+ +e+ e++l L +L+a+df FUN_001531-T1 948 MSHVQKMTEIRTD---IGHARAWIRLALEKKVLSKHLKQVLSSADLLRRRYKEYAFLRTDEEKEQFLYHLLSLTAVDF 1022 8889999999999...************************************************************99 PP == domain 3 score: 59.3 bits; conditional E-value: 1.1e-19 RUN 2 LcaalealLshGLkrsslraaglkkeksfwsllerv..............eklvpeaeellssvqeleqiksskspdgkgrawirlaLneklLe 81 Lc+ale++++ G+++ + ++++ +w++le+ +l + ++ v +++ ++ ++dgk++++++l+ ++lL+ FUN_001531-T1 1220 LCQALEQVFQCGFRS----SRLFRNNFFIWDILEKGqqylssvgedldpsDNLKRARKTFCTVVTRINNASHTIGKDGKFQSFVCLGARDHLLH 1309 9*************7....7789999999999999989999998888985445555555599999999999999******************** PP RUN 82 eylelllsnkellskyYepeAlladeefaeillslLvgLsaldfnlsv 129 +++ell ++ +++ +Y+ ++ +d+ ++ l++lL++L +++++l+ FUN_001531-T1 1310 DWFELLSTCP-ATTNMYDTPSFFRDSTLVQFLVELLQTLVEFNITLEA 1356 **********.9999****************************99975 PP >> uDENN uDENN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.6 0.0 2.1e-20 1.1e-16 2 63 .] 47 108 .. 46 108 .. 0.96 2 ? -1.7 0.0 1.2 6.1e+03 19 31 .. 1018 1030 .. 1008 1038 .. 0.83 Alignments for each domain: == domain 1 score: 61.6 bits; conditional E-value: 2.1e-20 uDENN 2 evldryPekdhedpplpdsipmFCfPeGlelqsederpeptffsFvlTdedgsrlYGaCltf 63 +vl ++P + +++p+++d++ m+ +P+Gl++++++e +ep+f+sF +T+edgsr+YG++l f FUN_001531-T1 47 KVLVHFPSNVDWNPFDEDAVRMLSLPQGLKFKKQSEHHEPSFHSFLITREDGSRVYGCALKF 108 89*****************************8888889*********************988 PP == domain 2 score: -1.7 bits; conditional E-value: 1.2 uDENN 19 dsipmFCfPeGle 31 +++ FCf +G + FUN_001531-T1 1018 TAVDFFCFTNGFQ 1030 57889***99975 PP >> PLAT PLAT/LH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.1 0.1 2.3e-16 1.2e-12 1 115 [. 1036 1140 .. 1036 1142 .. 0.88 Alignments for each domain: == domain 1 score: 49.1 bits; conditional E-value: 2.3e-16 PLAT 1 yqvkvvtgdkkgagt.dadvyislygkvgksaqleltldtsgpdfergaedsfevdtdwdlGallkinlhwdnkgisdewflksitvekpgetg 93 y+v+++tg++ g +t +a+v+++l g+ +++ +++ +e++f++++ + lG l+ +++ +dn+g+s wf+++i++ k++ t FUN_001531-T1 1036 YKVVIKTGKQLGGSTtTAQVWMTLAGNITDTGVMNIPK----------NENEFRFQHTN-LGVLTTLRIGHDNSGYSAGWFIEQIII-KNEVTS 1117 99********9887769*********999995555554..........5999****885.****************999********.799999 PP PLAT 94 kkvtFpcnsWvygsksy.ketrv 115 + + Fpc +W+ ++ ++ +++r FUN_001531-T1 1118 HIYRFPCGRWLAKNMDDgSTERL 1140 9************9998766665 PP >> dDENN dDENN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.5 2.4 7.6e-16 3.9e-12 1 49 [] 617 668 .. 617 668 .. 0.95 Alignments for each domain: == domain 1 score: 46.5 bits; conditional E-value: 7.6e-16 dDENN 1 FdkeaFlksqpsssreFlsqfleTQmFneFIeerless...sdpsidlFDer 49 Fdk++Fl++qp++ +Fls f+eTQmF++FI+ +++ + d i++FD+r FUN_001531-T1 617 FDKASFLSDQPQQFLPFLSPFTETQMFASFIDMKIMGTwgeLDSRIAVFDQR 668 9***********99***********************777678*******97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1363 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1678 (0.065688); expected 510.9 (0.02) Passed bias filter: 881 (0.0344882); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.49u 0.42s 00:00:00.90 Elapsed: 00:00:00.43 # Mc/sec: 12912.31 // Query: FUN_001532-T1 [L=929] Description: FUN_001532 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-50 168.2 10.3 1.3e-17 64.1 0.3 6.3 6 FF FF domain 9.2e-20 70.9 15.8 1.4e-09 38.3 5.6 3.0 2 WW WW domain 1.3e-19 70.2 1.1 4.4e-19 68.6 0.5 2.3 2 FF_PRPF40A PRPF40A-like, FF domain 6.9e-10 38.5 0.9 1.8e-05 24.4 0.3 2.6 2 WW_TCERG1 TCERG1 WW domain 0.00012 23.0 8.8 0.016 16.1 0.5 2.9 2 Glyco_hyd_101C Glycosyl hydrolase 101 beta sandwich domain 0.0028 17.6 0.0 0.064 13.3 0.0 2.7 2 WW_2 WW domain ------ inclusion threshold ------ 0.4 10.9 2.3 1.9 8.7 2.3 2.2 1 LUD_dom LUD domain Domain annotation for each model (and alignments): >> FF FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.1 0.3 3.6e-21 1.3e-17 1 50 [] 322 371 .. 322 371 .. 0.99 2 ! 25.6 0.6 3.6e-09 1.3e-05 1 49 [. 389 437 .. 389 438 .. 0.98 3 ! 10.9 0.2 0.00014 0.52 9 49 .. 461 510 .. 459 511 .. 0.71 4 ! 33.1 0.0 1.7e-11 6.1e-08 1 50 [] 536 591 .. 536 591 .. 0.98 5 ? -1.3 0.0 0.92 3.4e+03 7 33 .. 607 635 .. 597 644 .. 0.74 6 ! 35.2 0.0 3.7e-12 1.3e-08 2 50 .] 673 723 .. 672 723 .. 0.97 Alignments for each domain: == domain 1 score: 64.1 bits; conditional E-value: 3.6e-21 FF 1 kareaFkeLLkelkitpystWseikkkienDpRYkalrsgsereelFedy 50 +a++aFk+LL+e+++ ++s+W+ ++++i++DpRY al+++ e++++F++y FUN_001532-T1 322 EAKQAFKDLLREKEVPSNSSWDNAMRIIVSDPRYGALKKMNEKKQAFNEY 371 79***********************************************9 PP == domain 2 score: 25.6 bits; conditional E-value: 3.6e-09 FF 1 kareaFkeLLkelk.itpystWseikkkienDpRYkalrsgsereelFed 49 kare+ + L+ +k +++++W+ + +++e +p++ a+ +++r+++F+d FUN_001532-T1 389 KAREDLRSFLENHKkMHSSVRWRRAGEMFEGEPEWEAV-HERDRKDVFDD 437 89************************************.*********99 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00014 FF 9 LLkelk....itpystWseikkkienDpRY...kal..rsgsereelFed 49 +L+ ++ it+++tW e++++++++p Y + + +++ + +Fe+ FUN_001532-T1 461 MLQVYNtmssITYRTTWLEALQMLKEHPSYkddEEIqdCEKEDMLIAFEE 510 5555666667********************44444455666666666655 PP == domain 4 score: 33.1 bits; conditional E-value: 1.7e-11 FF 1 kareaFkeLLkelk....itpystWseikkkienDpRYkal..rsgsereelFedy 50 k+re F LL+el+ ++++s W + +++i+ D R+ ++ ++gs++++lF+ y FUN_001532-T1 536 KNREGFLVLLEELHkrgkLHSMSLWVDLYPTISADVRFTNIvgQPGSTPLDLFKFY 591 799**************************************************987 PP == domain 5 score: -1.3 bits; conditional E-value: 0.92 FF 7 keLLkelk..itpystWseikkkienDpR 33 ke Lk+l ++ ++ +se+ ++ + D+R FUN_001532-T1 607 KEILKDLDytVDVNTGFSEFNELVRGDDR 635 56677777777777777777766666665 PP == domain 6 score: 35.2 bits; conditional E-value: 3.7e-12 FF 2 areaFkeLLkelk..itpystWseikkkienDpRYkalrsgsereelFedy 50 +++aF++LLk + i+ +stW+e+++++ Dp + a++ + er ++F+++ FUN_001532-T1 673 RESAFRQLLKTCSpaIEDNSTWEEVRERLDGDPAFTAVTVEAERIRIFNEH 723 689**********************************************98 PP >> WW WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.3 5.6 3.9e-13 1.4e-09 3 31 .] 175 202 .. 173 202 .. 0.96 2 ! 37.1 2.5 9.1e-13 3.3e-09 3 31 .] 216 243 .. 215 243 .. 0.96 Alignments for each domain: == domain 1 score: 38.3 bits; conditional E-value: 3.9e-13 WW 3 pgWeeawdpdsGrvYYyNhnTgetqWekP 31 ++W+e++ pd Gr+Y+yN++T++++W kP FUN_001532-T1 175 TPWTEHKAPD-GRTYFYNTETKVSTWQKP 202 69********.*****************9 PP == domain 2 score: 37.1 bits; conditional E-value: 9.1e-13 WW 3 pgWeeawdpdsGrvYYyNhnTgetqWekP 31 ++W+e++ ++ G++YY+N++T+e++W+ P FUN_001532-T1 216 CPWKEHKANT-GKIYYHNTETKESTWTIP 243 58********.***************998 PP >> FF_PRPF40A PRPF40A-like, FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 3.6 1.3e+04 7 24 .. 325 342 .. 321 345 .. 0.71 2 ! 68.6 0.5 1.2e-22 4.4e-19 1 59 [. 598 656 .. 598 657 .. 0.98 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 3.6 FF_PRPF40A 7 kdikdvlkdkkfevtstt 24 kd l +k + +s++ FUN_001532-T1 325 QAFKDLLREKEVPSNSSW 342 555888888888777777 PP == domain 2 score: 68.6 bits; conditional E-value: 1.2e-22 FF_PRPF40A 1 qyredkkdikdvlkdkkfevtstttfeeFkaaisedrrtaniddgnlkliFerLlekak 59 ++ e+kk+ik++lkd +++v+++t f eF +++++d+r++++d+gn+k++F++ +eka+ FUN_001532-T1 598 RFSEEKKIIKEILKDLDYTVDVNTGFSEFNELVRGDDRSQTLDPGNVKMTFNHFIEKAE 656 689*******************************************************8 PP >> WW_TCERG1 TCERG1 WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.3 4.8e-09 1.8e-05 12 45 .. 174 207 .. 167 215 .. 0.87 2 ! 12.0 0.0 3.5e-05 0.13 22 46 .. 225 249 .. 212 255 .. 0.84 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 4.8e-09 WW_TCERG1 12 gtpwcvVWTgddkvFFfNPttrlSvWerPeeLkg 45 tpw+ d++++F+N +t++S W++P+eLk FUN_001532-T1 174 QTPWTEHKAPDGRTYFYNTETKVSTWQKPNELKT 207 5788888889**********************96 PP == domain 2 score: 12.0 bits; conditional E-value: 3.5e-05 WW_TCERG1 22 ddkvFFfNPttrlSvWerPeeLkgr 46 +k++++N +t+ S W P+eL + FUN_001532-T1 225 TGKIYYHNTETKESTWTIPKELAEL 249 689*******************875 PP >> Glyco_hyd_101C Glycosyl hydrolase 101 beta sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 1.9 0.00029 1 13 100 .. 128 212 .. 122 216 .. 0.65 2 ! 16.1 0.5 4.3e-06 0.016 58 98 .. 217 251 .. 209 256 .. 0.84 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00029 Glyco_hyd_101C 13 vtkweenevkltggtkvt.vkdaaatrertitldgtevlkg..dayLlPWnadadgkkekddeeklYhynpkggtstwtLpkkwakkssvk 100 v++++e+e k+t++ + t +++ + ++ ++ ++v k + +PW+ ++k+ + + Y+yn++ stw+ p+++++ +++ FUN_001532-T1 128 VKQMQEQESKATDSPSQTnKTEELDGKVEEVKKEKKKVKKPkpKEKQTPWT------EHKAPDGRTYFYNTETKVSTWQKPNELKTPGEIQ 212 556666666644443333033333334456666666776653355668888......34566679****************9998877666 PP == domain 2 score: 16.1 bits; conditional E-value: 4.3e-06 Glyco_hyd_101C 58 PWnadadgkkekddeeklYhynpkggtstwtLpkkwakkss 98 PW+ ++k+++ k+Y++n++ +stwt+pk++a+ ++ FUN_001532-T1 217 PWK------EHKANTGKIYYHNTETKESTWTIPKELAELKE 251 666......5678899*******************998776 PP >> WW_2 WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.3 0.0 1.7e-05 0.064 12 33 .. 177 198 .. 169 200 .. 0.85 2 ? 0.7 0.0 0.15 5.4e+02 20 33 .. 226 239 .. 221 241 .. 0.86 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.7e-05 WW_2 12 WIPQaTpDGRLFYFNTLTGVST 33 W pDGR +++NT T VST FUN_001532-T1 177 WTEHKAPDGRTYFYNTETKVST 198 556668***************9 PP == domain 2 score: 0.7 bits; conditional E-value: 0.15 WW_2 20 GRLFYFNTLTGVST 33 G+++Y NT T ST FUN_001532-T1 226 GKIYYHNTETKEST 239 99******997777 PP >> LUD_dom LUD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 2.3 0.00052 1.9 16 85 .. 315 390 .. 306 392 .. 0.71 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00052 LUD_dom 16 yyaktaeealelilelikegsvvseggstdlgeigl....apalhkgreevldlfekkl..taeareelrekalta 85 y+ +t+eea+++ ++l++e++v s + i++ al+k++e++ + e k+ + e++ee r+ka +a FUN_001532-T1 315 YIYETKEEAKQAFKDLLREKEVPSNSSWDNAMRIIVsdprYGALKKMNEKKQAFNEYKTkrANEEKEEQRQKAKKA 390 78899***************99555444444566668888555555555444444444444799999999999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (929 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4012 (0.157056); expected 510.9 (0.02) Passed bias filter: 758 (0.0296731); expected 510.9 (0.02) Passed Vit filter: 310 (0.0121354); expected 25.5 (0.001) Passed Fwd filter: 138 (0.00540223); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 1.36u 0.45s 00:00:01.81 Elapsed: 00:00:00.48 # Mc/sec: 7782.07 // Query: FUN_001532-T2 [L=904] Description: FUN_001532 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-50 168.1 10.6 1.3e-17 64.1 0.3 6.3 6 FF FF domain 1.3e-19 70.3 1.1 4.2e-19 68.6 0.5 2.3 2 FF_PRPF40A PRPF40A-like, FF domain 2.8e-18 66.1 20.6 1.4e-09 38.3 5.6 3.0 3 WW WW domain 6.4e-10 38.6 0.9 1.7e-05 24.4 0.3 2.6 2 WW_TCERG1 TCERG1 WW domain 0.00011 23.0 8.8 0.015 16.2 0.5 2.8 2 Glyco_hyd_101C Glycosyl hydrolase 101 beta sandwich domain 0.0026 17.7 0.0 0.062 13.4 0.0 2.7 2 WW_2 WW domain ------ inclusion threshold ------ 0.38 10.9 2.3 1.8 8.7 2.3 2.2 1 LUD_dom LUD domain Domain annotation for each model (and alignments): >> FF FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.1 0.3 3.5e-21 1.3e-17 1 50 [] 322 371 .. 322 371 .. 0.99 2 ! 25.7 0.6 3.5e-09 1.3e-05 1 49 [. 389 437 .. 389 438 .. 0.98 3 ! 11.0 0.2 0.00014 0.51 9 49 .. 461 510 .. 459 511 .. 0.71 4 ! 33.2 0.0 1.6e-11 5.9e-08 1 50 [] 536 591 .. 536 591 .. 0.98 5 ? -1.1 0.0 0.82 3e+03 7 32 .. 607 634 .. 596 644 .. 0.70 6 ! 35.3 0.0 3.5e-12 1.3e-08 2 50 .] 673 723 .. 672 723 .. 0.97 Alignments for each domain: == domain 1 score: 64.1 bits; conditional E-value: 3.5e-21 FF 1 kareaFkeLLkelkitpystWseikkkienDpRYkalrsgsereelFedy 50 +a++aFk+LL+e+++ ++s+W+ ++++i++DpRY al+++ e++++F++y FUN_001532-T2 322 EAKQAFKDLLREKEVPSNSSWDNAMRIIVSDPRYGALKKMNEKKQAFNEY 371 79***********************************************9 PP == domain 2 score: 25.7 bits; conditional E-value: 3.5e-09 FF 1 kareaFkeLLkelk.itpystWseikkkienDpRYkalrsgsereelFed 49 kare+ + L+ +k +++++W+ + +++e +p++ a+ +++r+++F+d FUN_001532-T2 389 KAREDLRSFLENHKkMHSSVRWRRAGEMFEGEPEWEAV-HERDRKDVFDD 437 89************************************.*********99 PP == domain 3 score: 11.0 bits; conditional E-value: 0.00014 FF 9 LLkelk....itpystWseikkkienDpRY...kal..rsgsereelFed 49 +L+ ++ it+++tW e++++++++p Y + + +++ + +Fe+ FUN_001532-T2 461 MLQVYNtmssITYRTTWLEALQMLKEHPSYkddEEIqdCEKEDMLIAFEE 510 5555666667********************44444455666666666655 PP == domain 4 score: 33.2 bits; conditional E-value: 1.6e-11 FF 1 kareaFkeLLkelk....itpystWseikkkienDpRYkal..rsgsereelFedy 50 k+re F LL+el+ ++++s W + +++i+ D R+ ++ ++gs++++lF+ y FUN_001532-T2 536 KNREGFLVLLEELHkrgkLHSMSLWVDLYPTISADVRFTNIvgQPGSTPLDLFKFY 591 799**************************************************987 PP == domain 5 score: -1.1 bits; conditional E-value: 0.82 FF 7 keLLkelk..itpystWseikkkienDp 32 ke Lk+l ++ ++ +se+ ++ + D+ FUN_001532-T2 607 KEILKDLDytVDVNTGFSEFNELVRGDD 634 4566666666666666666666666665 PP == domain 6 score: 35.3 bits; conditional E-value: 3.5e-12 FF 2 areaFkeLLkelk..itpystWseikkkienDpRYkalrsgsereelFedy 50 +++aF++LLk + i+ +stW+e+++++ Dp + a++ + er ++F+++ FUN_001532-T2 673 RESAFRQLLKTCSpaIEDNSTWEEVRERLDGDPAFTAVTVEAERIRIFNEH 723 689**********************************************98 PP >> FF_PRPF40A PRPF40A-like, FF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 3.5 1.3e+04 7 24 .. 325 342 .. 321 345 .. 0.71 2 ! 68.6 0.5 1.2e-22 4.2e-19 1 59 [. 598 656 .. 598 657 .. 0.98 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 3.5 FF_PRPF40A 7 kdikdvlkdkkfevtstt 24 kd l +k + +s++ FUN_001532-T2 325 QAFKDLLREKEVPSNSSW 342 555888888888777777 PP == domain 2 score: 68.6 bits; conditional E-value: 1.2e-22 FF_PRPF40A 1 qyredkkdikdvlkdkkfevtstttfeeFkaaisedrrtaniddgnlkliFerLlekak 59 ++ e+kk+ik++lkd +++v+++t f eF +++++d+r++++d+gn+k++F++ +eka+ FUN_001532-T2 598 RFSEEKKIIKEILKDLDYTVDVNTGFSEFNELVRGDDRSQTLDPGNVKMTFNHFIEKAE 656 689*******************************************************8 PP >> WW WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.3 5.6 3.8e-13 1.4e-09 3 31 .] 175 202 .. 173 202 .. 0.96 2 ! 37.1 2.5 8.8e-13 3.2e-09 3 31 .] 216 243 .. 215 243 .. 0.96 3 ? -3.8 0.1 5.6 2e+04 3 9 .. 421 427 .. 420 432 .. 0.75 Alignments for each domain: == domain 1 score: 38.3 bits; conditional E-value: 3.8e-13 WW 3 pgWeeawdpdsGrvYYyNhnTgetqWekP 31 ++W+e++ pd Gr+Y+yN++T++++W kP FUN_001532-T2 175 TPWTEHKAPD-GRTYFYNTETKVSTWQKP 202 69********.*****************9 PP == domain 2 score: 37.1 bits; conditional E-value: 8.8e-13 WW 3 pgWeeawdpdsGrvYYyNhnTgetqWekP 31 ++W+e++ ++ G++YY+N++T+e++W+ P FUN_001532-T2 216 CPWKEHKANT-GKIYYHNTETKESTWTIP 243 58********.***************998 PP == domain 3 score: -3.8 bits; conditional E-value: 5.6 WW 3 pgWeeaw 9 p+We+++ FUN_001532-T2 421 PEWEAVH 427 89*9986 PP >> WW_TCERG1 TCERG1 WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.3 4.7e-09 1.7e-05 12 45 .. 174 207 .. 167 215 .. 0.87 2 ! 12.1 0.0 3.4e-05 0.12 22 46 .. 225 249 .. 212 255 .. 0.84 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 4.7e-09 WW_TCERG1 12 gtpwcvVWTgddkvFFfNPttrlSvWerPeeLkg 45 tpw+ d++++F+N +t++S W++P+eLk FUN_001532-T2 174 QTPWTEHKAPDGRTYFYNTETKVSTWQKPNELKT 207 5788888889**********************96 PP == domain 2 score: 12.1 bits; conditional E-value: 3.4e-05 WW_TCERG1 22 ddkvFFfNPttrlSvWerPeeLkgr 46 +k++++N +t+ S W P+eL + FUN_001532-T2 225 TGKIYYHNTETKESTWTIPKELAEL 249 689*******************875 PP >> Glyco_hyd_101C Glycosyl hydrolase 101 beta sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 1.9 0.00028 1 13 100 .. 128 212 .. 122 216 .. 0.65 2 ! 16.2 0.5 4.2e-06 0.015 58 98 .. 217 251 .. 209 256 .. 0.84 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00028 Glyco_hyd_101C 13 vtkweenevkltggtkvt.vkdaaatrertitldgtevlkg..dayLlPWnadadgkkekddeeklYhynpkggtstwtLpkkwakkssvk 100 v++++e+e k+t++ + t +++ + ++ ++ ++v k + +PW+ ++k+ + + Y+yn++ stw+ p+++++ +++ FUN_001532-T2 128 VKQMQEQESKATDSPSQTnKTEELDGKVEEVKKEKKKVKKPkpKEKQTPWT------EHKAPDGRTYFYNTETKVSTWQKPNELKTPGEIQ 212 556666666644443333033333334456666666776653355668888......34566679****************9998877666 PP == domain 2 score: 16.2 bits; conditional E-value: 4.2e-06 Glyco_hyd_101C 58 PWnadadgkkekddeeklYhynpkggtstwtLpkkwakkss 98 PW+ ++k+++ k+Y++n++ +stwt+pk++a+ ++ FUN_001532-T2 217 PWK------EHKANTGKIYYHNTETKESTWTIPKELAELKE 251 666......5678899*******************998776 PP >> WW_2 WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.0 1.7e-05 0.062 12 33 .. 177 198 .. 169 200 .. 0.85 2 ? 0.8 0.0 0.14 5.3e+02 20 33 .. 226 239 .. 221 241 .. 0.86 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 1.7e-05 WW_2 12 WIPQaTpDGRLFYFNTLTGVST 33 W pDGR +++NT T VST FUN_001532-T2 177 WTEHKAPDGRTYFYNTETKVST 198 556668***************9 PP == domain 2 score: 0.8 bits; conditional E-value: 0.14 WW_2 20 GRLFYFNTLTGVST 33 G+++Y NT T ST FUN_001532-T2 226 GKIYYHNTETKEST 239 99******997777 PP >> LUD_dom LUD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 2.3 0.0005 1.8 16 85 .. 315 390 .. 306 392 .. 0.71 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0005 LUD_dom 16 yyaktaeealelilelikegsvvseggstdlgeigl....apalhkgreevldlfekkl..taeareelrekalta 85 y+ +t+eea+++ ++l++e++v s + i++ al+k++e++ + e k+ + e++ee r+ka +a FUN_001532-T2 315 YIYETKEEAKQAFKDLLREKEVPSNSSWDNAMRIIVsdprYGALKKMNEKKQAFNEYKTkrANEEKEEQRQKAKKA 390 78899***************99555444444566668888555555555444444444444799999999999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (904 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3888 (0.152202); expected 510.9 (0.02) Passed bias filter: 728 (0.0284987); expected 510.9 (0.02) Passed Vit filter: 298 (0.0116657); expected 25.5 (0.001) Passed Fwd filter: 135 (0.00528479); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 1.28u 0.45s 00:00:01.73 Elapsed: 00:00:00.47 # Mc/sec: 7780.10 // Query: FUN_001533-T1 [L=439] Description: FUN_001533 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-25 90.1 6.3 9.2e-25 87.8 6.3 2.1 1 PIP49_C Protein-kinase domain of FAM69 4.8e-14 52.9 0.1 1.1e-13 51.8 0.1 1.5 1 PIP49_N N-term cysteine-rich ER, FAM69 Domain annotation for each model (and alignments): >> PIP49_C Protein-kinase domain of FAM69 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.8 6.3 7.2e-29 9.2e-25 3 170 .. 160 385 .. 158 410 .. 0.90 Alignments for each domain: == domain 1 score: 87.8 bits; conditional E-value: 7.2e-29 PIP49_C 3 allqnneylllqllqdkehfpkllgsCGdlyvvesveavellek.................................................... 46 +llq+ne ++l++l+++eh+ ++g+C lyv e+v++v ++ FUN_001533-T1 160 SLLQQNEAMMLMALNNSEHTVDFYGYCAGLYVLEKVPHVTAKVFeekwelidlsflpeavepiqtaidnlggiilqavfsflqylcahfpnylpmk 255 89***********************************9876544899************************************************* PP PIP49_C 47 ...lrraldqfleeswearakiaislLelveeleenfleslylcdvklenfgvtedgklklvDaeavvvedklerslseqkcekdeDCsf...fdC 136 + ++ +s + + ++a+sl++ el++n+++ + cd +l+nfg+t+++ +k++D++ ++ + +++ l++++c+ d+DC + C FUN_001533-T1 256 infMLHTFLATHVPSKREKFRLAYSLIDATLELSNNPYGLVISCDANLHNFGYTSNFLVKFIDLDLTYPLTFVKNLLKKKNCTCDSDCWTgvsEIC 351 8887777777788899999*********************************************************************7654578* PP PIP49_C 137 lskcdkekrrCssevannNlqivCeklldkllrg 170 s c+ ++ C+se + + l ivCe++ +k+++ FUN_001533-T1 352 CSACNTTTGYCTSEMQYQDLHIVCEAIIPKIFSK 385 **************************98887443 PP >> PIP49_N N-term cysteine-rich ER, FAM69 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.8 0.1 8.2e-18 1.1e-13 35 120 .. 29 114 .. 5 123 .. 0.84 Alignments for each domain: == domain 1 score: 51.8 bits; conditional E-value: 8.2e-18 PIP49_N 35 lCrgheckniiCdkYkkgiisGsaCesLCeketlsllkClstkpknqvysgkwkdkevvikcqleealksdleeeseprkeaelfd 120 C + + ++iC + g +sGs+C++LC +e+ + +Cls p + ++ ++w+++evv+k +++ + ++++e+++ ke+++++ FUN_001533-T1 29 KCDMILVLEKICSAFMAGDVSGSLCKDLCVHENFHFAECLSIVPAKTIFGANWREREVVVKINMSWFEELEKRQEFAKGKEVKSYE 114 377777789*******************************************************9999999999999999988775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (439 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1032 (0.0403993); expected 510.9 (0.02) Passed bias filter: 562 (0.0220004); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.36s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4227.14 // Query: FUN_001534-T1 [L=1059] Description: FUN_001534 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-15 57.3 4.6 1.7e-15 57.1 0.6 3.1 2 INCENP_ARK-bind Inner centromere protein, ARK binding region Domain annotation for each model (and alignments): >> INCENP_ARK-bind Inner centromere protein, ARK binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.2 0.061 1.6e+03 2 13 .. 74 85 .. 73 93 .. 0.78 2 ! 57.1 0.6 6.8e-20 1.7e-15 1 55 [] 971 1029 .. 971 1029 .. 0.95 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.061 INCENP_ARK-bind 2 insDdedddede 13 +sDd++ d +e FUN_001534-T1 74 QSSDDSTADANE 85 68*******998 PP == domain 2 score: 57.1 bits; conditional E-value: 6.8e-20 INCENP_ARK-bind 1 dinsDdedddedeprkklpsWAespeLrqaLirq..etiDpdeiFGp..ipplnleeiF 55 d++sDd++dded+p+kk+p+WA++p+L + + +q ++iD+++iFG +p l lee+F FUN_001534-T1 971 DLHSDDSTDDEDNPKKKIPAWAREPALTATIFKQaySDIDVNTIFGFdkMPALILEEVF 1029 799******************************************764488*******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1059 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4450 (0.174202); expected 510.9 (0.02) Passed bias filter: 905 (0.0354277); expected 510.9 (0.02) Passed Vit filter: 486 (0.0190252); expected 25.5 (0.001) Passed Fwd filter: 121 (0.00473674); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 1.47u 0.46s 00:00:01.93 Elapsed: 00:00:00.52 # Mc/sec: 8166.14 // Query: FUN_001535-T1 [L=1102] Description: FUN_001535 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-14 53.1 0.0 1.3e-13 51.6 0.0 1.8 2 Lipase_3 Lipase (class 3) ------ inclusion threshold ------ 0.26 11.7 0.1 0.54 10.7 0.1 1.5 1 DUF7470 Family of unknown function (DUF7470) Domain annotation for each model (and alignments): >> Lipase_3 Lipase (class 3) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.1 0.87 1.1e+04 72 86 .. 68 82 .. 68 84 .. 0.87 2 ! 51.6 0.0 9.9e-18 1.3e-13 1 137 [. 412 548 .. 412 550 .. 0.87 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 0.87 Lipase_3 72 LGGalAsLaaldlve 86 +GG lA+L+a+ ++e FUN_001535-T1 68 MGGYLALLFATNIME 82 69********99876 PP == domain 2 score: 51.6 bits; conditional E-value: 9.9e-18 Lipase_3 1 vvafrGteslkewltdldfslteakellek.ggkvhegfleayesvreqveeelke.llekyp.....dykivvtGHSLGGalAsLaaldlvengl 89 vv++rGt sl+++ltd+ + ++ + + h+g+++a+ ++ ++e + + ++++ p +y++v++GHSLG+++As++a+ l+ + FUN_001535-T1 412 VVTIRGTLSLQDILTDFSLEAEKIPLEGGDpSWFGHKGMIKAALYIKRKLESGILTrAFHSDPdrhteSYRLVLVGHSLGAGTASILAILLRPYY- 506 799**************999999998866577788*********9999999988776999999999888***********************999. PP Lipase_3 90 ressrvkvvtfGqPrvgnkefaklvdeqvekkvlrvvnkrDiVPrlpp 137 ++ +++f++P + a +++ +++v++vv +D++Prl++ FUN_001535-T1 507 ---PDLFCYAFSPPGANLSLSAAKYT---RDFVISVVVGKDMIPRLSL 548 ...67*******99874443344444...589*************975 PP >> DUF7470 Family of unknown function (DUF7470) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.1 4.2e-05 0.54 22 50 .. 12 40 .. 3 45 .. 0.89 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 4.2e-05 DUF7470 22 liAlenlivAaGlalvlaGlgLvvkglvs 50 ++A+++ ++ G+a+vl Gl +v +++ FUN_001535-T1 12 MVASDDFVIPFGIAFVLRGLWMVTLSVAV 40 79*********************998875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 845 (0.0330789); expected 510.9 (0.02) Passed bias filter: 492 (0.0192601); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.46u 0.37s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 10537.81 // Query: FUN_001536-T1 [L=243] Description: FUN_001536 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.1 12.7 0.0 9 6.4 0.0 2.1 2 PhaC_N Poly-beta-hydroxybutyrate polymerase (PhaC) N-termi Domain annotation for each model (and alignments): >> PhaC_N Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.0 0.00035 9 22 77 .. 19 70 .. 2 78 .. 0.80 2 ? 4.6 0.0 0.0012 32 49 113 .. 76 139 .. 70 146 .. 0.82 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.00035 PhaC_N 22 aylltsklleelveevegldektrerveflvrqlldalaPsnflltnpevlkeale 77 +yl +++ +++ v++ld + r+ ++l+ q + + P ++ np++++++++ FUN_001536-T1 19 SYLPNAR----WINPVSSLDLAMRRPHQLLLAQQVGLTVPKSIITNNPAAVEKLFD 70 5555555....566777899999*****************************9986 PP == domain 2 score: 4.6 bits; conditional E-value: 0.0012 PhaC_N 49 eflvrqlldalaPsnflltnpevlkealeseGeslvkGlenlleDlergkgelkisqtdesafev 113 +++++ l +++ P n+++ e+++e++ + +s+ k + + ++l + ++l+i+++ ++ f v FUN_001536-T1 76 RLVFKTLGQLFVPPNTMVFTNEITREFVTQSPDSISKRPA-IYQELVERISDLRITIVGDELFVV 139 6788899999*******9999*******999999988655.556666666779999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (243 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 577 (0.0225876); expected 510.9 (0.02) Passed bias filter: 538 (0.0210609); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2432.66 // Query: FUN_001536-T2 [L=337] Description: FUN_001536 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-05 24.0 0.0 7.4e-05 23.3 0.0 1.3 1 ATPgraspMvdD MvdD pre-ATP grasp domain ------ inclusion threshold ------ 0.17 12.4 0.0 0.38 11.3 0.0 1.5 1 Peptidase_S48 Peptidase family S48 Domain annotation for each model (and alignments): >> ATPgraspMvdD MvdD pre-ATP grasp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 5.8e-09 7.4e-05 2 119 .. 5 126 .. 4 128 .. 0.89 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 5.8e-09 ATPgraspMvdD 2 vLiithsqDnet.idlVaealeekgaka..lRfdtDkfptevqlsaalen.gkekvlleeeeeeldleeveavWyRrlalgaklpeeldkqyreas 93 +L+i s +++ id +++++++++ +a +R+d++ + +++++ + + +++++ ++e++ +e++++vWy + + ++ ++ l+ +e + FUN_001536-T2 5 ILCIGNSVSYDChIDSIEKHVKALDSEAklVRLDVEVDSNFIEINTGGNPeKATSCFVIVDGERIPSESITSVWYFWMPCYPETDNLLEFMGKEFA 100 78888887777669********998766559*************99877625567788999*********************************** PP ATPgraspMvdD 94 veEsratlegfleslkkafwldklek 119 ++E ++++ + l +a+w++++++ FUN_001536-T2 101 TTEWGRVIRSLESYLPNARWINPVSS 126 **********9999********9986 PP >> Peptidase_S48 Peptidase family S48 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 2.9e-05 0.38 52 105 .. 76 129 .. 70 144 .. 0.90 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.9e-05 Peptidase_S48 52 qlpylWlekypwqpgesrisgksLtseekkeleaklpkdlPkarlinslefleL 105 ++ y W+ yp +++ gk+++++e + ++l++ lP+ar in + l+L FUN_001536-T2 76 SVWYFWMPCYPETDNLLEFMGKEFATTEWGRVIRSLESYLPNARWINPVSSLDL 129 56799*****************************************98876666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (337 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 773 (0.0302603); expected 510.9 (0.02) Passed bias filter: 729 (0.0285379); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3423.42 // Query: FUN_001537-T1 [L=168] Description: FUN_001537 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-14 53.7 0.0 4.1e-09 36.9 0.0 2.1 2 Crystall Beta/Gamma crystallin ------ inclusion threshold ------ 0.029 14.7 0.0 0.039 14.3 0.0 1.1 1 Phage_term_sma Putative bacteriophage terminase small subuni Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 2.5e-06 0.032 10 54 .. 8 49 .. 3 51 .. 0.88 2 ! 36.9 0.0 3.2e-13 4.1e-09 2 81 .. 86 166 .. 85 167 .. 0.93 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.5e-06 Crystall 10 fqGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrGr 54 G s ++ d ++l++ g ++ S+ ++G+W++Y++++f+ r FUN_001537-T1 8 ADGASADIKHDEKDLKSIGTFT---SAVAKDGTWIFYKYKDFNDR 49 5789999999999999977766...*****************976 PP == domain 2 score: 36.9 bits; conditional E-value: 3.2e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr.vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+l+e+ + G++ ++++d+++++ + vs V +G + ++ +pn++G+ +l g+y++ +++ + ndr++S+R FUN_001537-T1 86 IVLFEHFYYGGKREHYNSDVANVDFPSERPEgVSGSIVIGGKFDVFTKPNWNGTSSILSDGQYPTPTTMNIGNDRVQSIRK 166 89*********************97555555699999******************************************96 PP >> Phage_term_sma Putative bacteriophage terminase small subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 3.1e-06 0.039 92 143 .. 4 56 .. 2 81 .. 0.86 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 3.1e-06 Phage_term_sma 92 tiydadgnvekvkvkekeldkdslvammvakagnpelynptewr.rlqqeess 143 t+ydadg +k ek+l + vak g +y+ ++ rl+++es FUN_001537-T1 4 TLYDADGASADIKHDEKDLKSIGTFTSAVAKDGTWIFYKYKDFNdRLDNKESW 56 89************************************999985488888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 678 (0.0265414); expected 510.9 (0.02) Passed bias filter: 565 (0.0221178); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1659.15 // Query: FUN_001539-T1 [L=168] Description: FUN_001539 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-14 53.7 0.0 4.1e-09 36.9 0.0 2.1 2 Crystall Beta/Gamma crystallin ------ inclusion threshold ------ 0.029 14.7 0.0 0.039 14.3 0.0 1.1 1 Phage_term_sma Putative bacteriophage terminase small subuni Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 2.5e-06 0.032 10 54 .. 8 49 .. 3 51 .. 0.88 2 ! 36.9 0.0 3.2e-13 4.1e-09 2 81 .. 86 166 .. 85 167 .. 0.93 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.5e-06 Crystall 10 fqGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrGr 54 G s ++ d ++l++ g ++ S+ ++G+W++Y++++f+ r FUN_001539-T1 8 ADGASADIKHDEKDLKSIGTFT---SAVAKDGTWIFYKYKDFNDR 49 5789999999999999977766...*****************976 PP == domain 2 score: 36.9 bits; conditional E-value: 3.2e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr.vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+l+e+ + G++ ++++d+++++ + vs V +G + ++ +pn++G+ +l g+y++ +++ + ndr++S+R FUN_001539-T1 86 IVLFEHFYYGGKREHYNSDVANVDFPSERPEgVSGSIVIGGKFDVFTKPNWNGTSSILSDGQYPTPTTMNIGNDRVQSIRK 166 89*********************97555555699999******************************************96 PP >> Phage_term_sma Putative bacteriophage terminase small subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 3.1e-06 0.039 92 143 .. 4 56 .. 2 81 .. 0.86 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 3.1e-06 Phage_term_sma 92 tiydadgnvekvkvkekeldkdslvammvakagnpelynptewr.rlqqeess 143 t+ydadg +k ek+l + vak g +y+ ++ rl+++es FUN_001539-T1 4 TLYDADGASADIKHDEKDLKSIGTFTSAVAKDGTWIFYKYKDFNdRLDNKESW 56 89************************************999985488888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 678 (0.0265414); expected 510.9 (0.02) Passed bias filter: 565 (0.0221178); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1679.13 // Query: FUN_001540-T1 [L=168] Description: FUN_001540 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-14 53.4 0.0 4.1e-09 36.9 0.0 2.1 2 Crystall Beta/Gamma crystallin Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 1.5e-06 0.038 11 54 .. 9 49 .. 4 51 .. 0.87 2 ! 36.9 0.0 1.6e-13 4.1e-09 2 81 .. 86 166 .. 85 167 .. 0.93 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 1.5e-06 Crystall 11 qGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrGr 54 G s ++ +d ++l++ g ++ S+ ++G+W++Y++++f+ r FUN_001540-T1 9 YGASKDIKQDEKDLKSIGTFT---SAVAKDGTWIFYKYKDFNDR 49 688889999999999977766...*****************976 PP == domain 2 score: 36.9 bits; conditional E-value: 1.6e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr.vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+l+e+ + G++ ++++d+++++ + vs V +G + ++ +pn++G+ +l g+y++ +++ + ndr++S+R FUN_001540-T1 86 IVLFEHFYYGGKREHYNSDVANVDFPSERPEgVSGSIVIGGKFDVFTKPNWNGTSSILSDGQYPTPTTMNIGNDRVQSIRK 166 89*********************97555555699999******************************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 707 (0.0276766); expected 510.9 (0.02) Passed bias filter: 589 (0.0230573); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.22u 0.45s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1690.77 // Query: FUN_001540-T2 [L=168] Description: FUN_001540 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-14 53.4 0.0 4.1e-09 36.9 0.0 2.1 2 Crystall Beta/Gamma crystallin ------ inclusion threshold ------ 0.1 12.9 0.0 0.14 12.5 0.0 1.1 1 Phage_term_sma Putative bacteriophage terminase small subuni Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 3.1e-06 0.039 11 54 .. 9 49 .. 3 54 .. 0.86 2 ! 36.9 0.0 3.2e-13 4.1e-09 2 81 .. 86 166 .. 85 167 .. 0.93 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.1e-06 Crystall 11 qGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrGr 54 G s ++ d ++l++ g ++ S+ ++G+W++Y++++f+ r FUN_001540-T2 9 DGASKDIKHDEKDLKSIGTFT---SAVAKDGTWIFYKYKDFNDR 49 688889999999999977766...*****************987 PP == domain 2 score: 36.9 bits; conditional E-value: 3.2e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr.vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+l+e+ + G++ ++++d+++++ + vs V +G + ++ +pn++G+ +l g+y++ +++ + ndr++S+R FUN_001540-T2 86 IVLFEHFYYGGKREHYNSDVANVDFPSERPEgVSGSIVIGGKFDVFTKPNWNGTSSILSDGQYPTPTTMNIGNDRVQSIRK 166 89*********************97555555699999******************************************96 PP >> Phage_term_sma Putative bacteriophage terminase small subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 1.1e-05 0.14 92 134 .. 4 46 .. 2 77 .. 0.87 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.1e-05 Phage_term_sma 92 tiydadgnvekvkvkekeldkdslvammvakagnpelynptew 134 t+ydadg + +k ek+l + vak g +y+ ++ FUN_001540-T2 4 TLYDADGASKDIKHDEKDLKSIGTFTSAVAKDGTWIFYKYKDF 46 89*******************************9999987766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 622 (0.0243492); expected 510.9 (0.02) Passed bias filter: 515 (0.0201605); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1662.21 // Query: FUN_001541-T1 [L=194] Description: FUN_001541 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-07 29.5 0.0 0.049 14.2 0.0 2.2 2 Crystall Beta/Gamma crystallin Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.2 0.0 1.9e-06 0.049 11 54 .. 9 49 .. 4 51 .. 0.87 2 ! 13.2 0.0 3.9e-06 0.1 2 68 .. 86 153 .. 85 164 .. 0.82 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.9e-06 Crystall 11 qGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrGr 54 G s ++ +d ++l++ g ++ S+ ++G+W++Y++++f+ r FUN_001541-T1 9 YGASKDIKQDEKDLKSIGTFT---SAVAKDGTWIFYKYKDFNDR 49 688889999999999977766...*****************976 PP == domain 2 score: 13.2 bits; conditional E-value: 3.9e-06 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr.vsSikVesGaWvlYeepnfrGrqyllekgeyrdlse 68 i+l+e+ + G++ ++++d+++++ + vs V +G + ++ +pn++G+ + ++ r+l++ FUN_001541-T1 86 IVLFEHFYYGGKREHYNSDVANVDFPSERPEgVSGSIVIGGKFDVFTKPNWNGNIFRNLRKTLRNLHN 153 89*********************97555555699999****************998777777766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (194 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 797 (0.0311998); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1960.85 // Query: FUN_001542-T1 [L=168] Description: FUN_001542 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-14 54.0 0.0 4.1e-09 36.9 0.0 2.1 2 Crystall Beta/Gamma crystallin ------ inclusion threshold ------ 0.1 13.0 0.0 0.13 12.6 0.0 1.1 1 Phage_term_sma Putative bacteriophage terminase small subuni Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 2e-06 0.026 11 54 .. 9 49 .. 3 54 .. 0.87 2 ! 36.9 0.0 3.2e-13 4.1e-09 2 81 .. 86 166 .. 85 167 .. 0.93 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 2e-06 Crystall 11 qGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrGr 54 G s ++ +d ++l++ g ++ S+ ++G+W++Y++++f+ r FUN_001542-T1 9 DGASKDIKQDEKDLKSIGTFT---SAVAKDGTWIFYKYKDFNDR 49 688999999999999977766...*****************987 PP == domain 2 score: 36.9 bits; conditional E-value: 3.2e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr.vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+l+e+ + G++ ++++d+++++ + vs V +G + ++ +pn++G+ +l g+y++ +++ + ndr++S+R FUN_001542-T1 86 IVLFEHFYYGGKREHYNSDVANVDFPSERPEgVSGSIVIGGKFDVFTKPNWNGTSSILSDGQYPTPTTMNIGNDRVQSIRK 166 89*********************97555555699999******************************************96 PP >> Phage_term_sma Putative bacteriophage terminase small subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 1e-05 0.13 92 134 .. 4 46 .. 2 77 .. 0.87 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1e-05 Phage_term_sma 92 tiydadgnvekvkvkekeldkdslvammvakagnpelynptew 134 t+ydadg + +k ek+l + vak g +y+ ++ FUN_001542-T1 4 TLYDADGASKDIKQDEKDLKSIGTFTSAVAKDGTWIFYKYKDF 46 89*******************************9999987766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (168 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 638 (0.0249755); expected 510.9 (0.02) Passed bias filter: 526 (0.0205911); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1655.05 // Query: FUN_001543-T1 [L=136] Description: FUN_001543 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.015 15.8 0.0 0.8 10.4 0.0 2.2 2 Crystall Beta/Gamma crystallin Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 3.1e-05 0.8 32 54 .. 36 58 .. 9 60 .. 0.79 2 ? 3.7 0.0 0.0038 98 2 26 .. 92 116 .. 91 135 .. 0.86 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 3.1e-05 Crystall 32 rvsSikVesGaWvlYeepnfrGr 54 S+ G+W++Y++++f+ r FUN_001543-T1 36 TFVSAVATAGTWIFYKYKDFNDR 58 366888899***********987 PP == domain 2 score: 3.7 bits; conditional E-value: 0.0038 Crystall 2 itlyekenfqGrsveltedcpslqe 26 i+l+e+ + G++ +++d+++++ FUN_001543-T1 92 IVLFEHFYYGGHRKYYNSDVDNVNP 116 89*****************999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (136 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 519 (0.0203171); expected 510.9 (0.02) Passed bias filter: 388 (0.0151889); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.23u 0.41s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1380.76 // Query: FUN_001544-T1 [L=170] Description: FUN_001544 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-11 44.3 0.0 2.2e-07 31.4 0.0 2.2 2 Crystall Beta/Gamma crystallin Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.9 0.0 2.2e-05 0.55 10 53 .. 8 48 .. 5 51 .. 0.83 2 ! 31.4 0.0 8.7e-12 2.2e-07 2 80 .. 86 167 .. 85 169 .. 0.94 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 2.2e-05 Crystall 10 fqGrsveltedcpslqergfnsrvsSikVesGaWvlYeepnfrG 53 +G s ++++ + +l++ g + + V +G+W++Y+ ++f+ FUN_001544-T1 8 TRGASKDFQDSVTDLRSIGTFV---KASVREGTWIFYKFKDFNN 48 6788999999999999977766...4679************985 PP == domain 2 score: 31.4 bits; conditional E-value: 8.7e-12 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr...vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlR 80 i+l+++ ++ G s ++++c++++ + ++ +sS+ V++G++ ++ e G+ l++ ey++ +++ + + +i+S+R FUN_001544-T1 86 IVLFQHAHYGGPSRYYNDHCDNVNPDFPHETlagASSAIVLGGTFEVFTEVAGGGESSTLTEREYPTPEAMKVVTHKIRSVR 167 89**********************96655558899**********************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (170 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 449 (0.0175768); expected 510.9 (0.02) Passed bias filter: 359 (0.0140536); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1747.69 // Query: FUN_001545-T1 [L=169] Description: FUN_001545 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-13 49.6 0.0 3.3e-09 37.2 0.0 2.3 2 Crystall Beta/Gamma crystallin Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.0 3.7e-05 0.93 36 53 .. 31 48 .. 8 50 .. 0.72 2 ! 37.2 0.0 1.3e-13 3.3e-09 2 81 .. 85 167 .. 84 168 .. 0.95 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 3.7e-05 Crystall 36 ikVesGaWvlYeepnfrG 53 + V++G+W++Y++++f+ FUN_001545-T1 31 AIVKDGTWIFYKNKDFND 48 569*************85 PP == domain 2 score: 37.2 bits; conditional E-value: 1.3e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr...vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+++e+ + G++ ++ dc++l++ + + + vs + V++G + ++ +pn G l++g y++ +++ + nd+i+S+R FUN_001545-T1 85 IVMFEHFYYGGHRKYYNHDCDNLNADFPSGKaegVSGCIVLGGKFDAFTKPNGGGVSSTLTEGRYPTATTMNIGNDKIQSIRK 167 89**********************9777666888***********************************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (169 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 378 (0.0147974); expected 510.9 (0.02) Passed bias filter: 295 (0.0115482); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1691.14 // Query: FUN_001545-T2 [L=169] Description: FUN_001545 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.7e-13 49.0 0.0 4.8e-09 36.7 0.0 2.3 2 Crystall Beta/Gamma crystallin Domain annotation for each model (and alignments): >> Crystall Beta/Gamma crystallin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.0 3.7e-05 0.93 36 53 .. 31 48 .. 8 50 .. 0.72 2 ! 36.7 0.0 1.9e-13 4.8e-09 2 81 .. 85 167 .. 84 168 .. 0.95 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 3.7e-05 Crystall 36 ikVesGaWvlYeepnfrG 53 + V++G+W++Y++++f+ FUN_001545-T2 31 AIVKDGTWIFYKNKDFND 48 569*************85 PP == domain 2 score: 36.7 bits; conditional E-value: 1.9e-13 Crystall 2 itlyekenfqGrsveltedcpslqergfnsr...vsSikVesGaWvlYeepnfrGrqyllekgeyrdlsewgaendrigSlRr 81 i+++e+ + G++ ++ dc++l++ + + + vs + V++G + ++ +pn G l++g y++ +++ + nd+++S+R FUN_001545-T2 85 IVMFEHFYYGGHRKYYNHDCDNLNADFPSGKaegVSGCIVLGGKFDAFTKPNGGGVSSTLTEGRYPTATTMNIGNDKVQSIRK 167 89**********************9777666888***********************************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (169 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 377 (0.0147583); expected 510.9 (0.02) Passed bias filter: 290 (0.0113525); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1657.57 // Query: FUN_001546-T1 [L=188] Description: FUN_001546 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-19 70.1 6.1 4.1e-19 69.7 6.1 1.2 1 NDUF_B8 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASH Domain annotation for each model (and alignments): >> NDUF_B8 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.7 6.1 1.6e-23 4.1e-19 50 164 .. 53 170 .. 31 175 .. 0.81 Alignments for each domain: == domain 1 score: 69.7 bits; conditional E-value: 1.6e-23 NDUF_B8 50 pyddddlgaGdyPdlpkrsqderdPyeqWddrdlrrnWGelvhld...ldmyirdrldesetyvtWntikklllvlvalallafylgevyPs..kq 140 ++dd+ g GdyP+lp++s+++r ++ W d + rrn+ e++h d l+ ++ + ++ +ty++ +++ +++ v a++ ++ +l+ y + ++ FUN_001546-T1 53 DWPDDGYGLGDYPNLPDISYQRRQ-HKGWWDWQDRRNFNEPIHEDedgLNIWMMQEVECNDTYTPQQAL-MHMTVAFAIVGFIGFLSYLYDKtdRN 146 579*****************9987.6777778889********99444567788888888888887776.4555544555455555655554459* PP NDUF_B8 141 PvapkqypyddlylergddPrkep 164 P+ pk yp+++lylerg+dP+k p FUN_001546-T1 147 PAIPKEYPFNNLYLERGGDPNKDP 170 **********************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 539 (0.0211); expected 510.9 (0.02) Passed bias filter: 474 (0.0185555); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1861.78 // Query: FUN_001547-T1 [L=4196] Description: FUN_001547 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-160 534.1 0.1 3.9e-159 529.4 0.0 2.7 3 AAA_6 Hydrolytic ATP binding site of dynein motor r 3.3e-155 517.4 6.3 3.3e-155 517.4 6.3 3.6 3 DHC_N2 Dynein heavy chain, N-terminal region 2 3.6e-125 417.8 0.0 3.6e-125 417.8 0.0 2.5 3 Dynein_C Dynein heavy chain C-terminal domain 2.6e-99 332.2 2.6 9.1e-99 330.4 0.0 3.1 3 AAA_8 P-loop containing dynein motor region D4 5.2e-94 314.0 0.3 2.6e-91 305.1 0.1 3.6 3 AAA_9 ATP-binding dynein motor region 6.2e-81 270.8 0.1 2.7e-76 255.6 0.0 3.5 3 AAA_7 P-loop containing dynein motor region 1.6e-53 182.5 9.7 4.1e-53 181.1 9.7 1.8 1 MT Microtubule-binding stalk of dynein motor 3.3e-52 176.9 0.1 1.5e-51 174.7 0.0 2.3 1 AAA_lid_11 Dynein heavy chain AAA lid domain 3.1e-47 159.8 0.0 9.4e-47 158.2 0.0 1.9 1 Dynein_heavy Dynein heavy chain region D6 P-loop domain 7.9e-33 113.7 0.0 4.4e-32 111.3 0.0 2.4 1 Dynein_AAA_lid Dynein heavy chain AAA lid domain 1e-18 68.1 0.0 1.8e-07 31.7 0.0 5.6 4 AAA_5 AAA domain (dynein-related subfamily) 2.2e-18 66.9 0.5 1.7e-17 64.1 0.1 2.8 2 AAA_lid_1 AAA+ lid domain 4.5e-18 65.8 0.1 7.8e-17 61.9 0.1 3.0 2 DYN_lid Dynein heavy chain, ATPase lid domain 1.1e-06 29.0 0.0 0.049 13.8 0.0 3.1 2 DEAD DEAD/DEAH box helicase 3.6e-06 27.5 0.0 0.091 13.1 0.0 3.1 2 ResIII Type III restriction enzyme, res subunit 4.9e-06 27.5 0.2 1.4 9.8 0.0 5.1 4 AAA ATPase family associated with various cellula 5.1e-06 27.3 3.7 1.4 9.7 0.0 5.2 4 AAA_22 AAA domain 0.00017 21.6 0.0 0.7 9.7 0.0 3.1 2 Mg_chelatase Magnesium chelatase, subunit ChlI 0.00051 21.1 7.1 3 8.8 0.0 5.8 4 AAA_16 AAA ATPase domain 0.0083 16.3 0.1 1.4 9.1 0.0 3.5 3 nSTAND3 Novel STAND NTPase 3 0.0085 15.3 3.1 2.3 7.2 0.1 3.4 4 T2SSE Type II/IV secretion system protein ------ inclusion threshold ------ 0.014 16.4 2.9 31 5.6 0.0 4.8 3 RNA_helicase RNA helicase 0.027 14.7 0.4 18 5.5 0.0 3.5 3 AAA_30 AAA domain 0.19 12.7 5.0 2.9 8.9 0.0 4.4 2 AAA_18 AAA domain 0.54 10.9 3.8 96 3.6 0.0 4.3 4 AAA_19 AAA domain 0.84 10.4 2.4 65 4.3 0.1 3.7 3 AAA_33 AAA domain Domain annotation for each model (and alignments): >> AAA_6 Hydrolytic ATP binding site of dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 529.4 0.0 3.9e-162 3.9e-159 1 327 [] 1486 1812 .. 1486 1812 .. 1.00 2 ? -3.6 0.0 6 5.9e+03 312 327 .] 2161 2176 .. 2153 2176 .. 0.74 3 ? 1.4 0.0 0.18 1.8e+02 187 265 .. 2342 2426 .. 2323 2475 .. 0.69 Alignments for each domain: == domain 1 score: 529.4 bits; conditional E-value: 3.9e-162 AAA_6 1 YgyeYlgnserLviTpltdrcyltltqalklklggapaGpagtGKtEtvkdlakalaklvvvfncseeldykslgkifkGlaqsGaWgCfdeFn 94 YgyeYlgn++rLviTpltdrcyltlt al+lk+ggapaGpagtGKtEt+kdl+ka+a+++vvfncs++ld+ ++gk+fkGla++GaW+CfdeFn FUN_001547-T1 1486 YGYEYLGNTGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKAMAVQCVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFN 1579 9********************************************************************************************* PP AAA_6 95 rielevLSvvaqqlktiqqalkekkkkfvfegkeiklnksvgifitmnpgyagrteLPdnLkalfRpvammvpDleliaeimLfseGfkeakkL 188 ri++evLSvvaqq++tiqqal+++ ++f+feg e+ l++s+++fitmnpgyagrteLPdnLkalfRpvammvpD++liaei Lfs Gf+eak+L FUN_001547-T1 1580 RIDVEVLSVVAQQISTIQQALEARVDRFMFEGVELALRPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYALIAEISLFSFGFSEAKAL 1673 ********************************************************************************************** PP AAA_6 189 akklvtlyklaseqlskqkhYdfglralksvlktagslkraepeeseeklllralrdvnlpklvaeDvplfkglisdlFpgvelpksdyeelee 282 akk++t++kl+seqls+q+hYdfg+ra+k+v+++ag+lkr++pe+see ++lra+rdvn+pk++++D++lf+g++sdlFp+v+ ++ dy elee FUN_001547-T1 1674 AKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPEMSEELIVLRAIRDVNVPKFLQDDLKLFRGIVSDLFPHVKEQPIDYGELEE 1767 ********************************************************************************************** PP AAA_6 283 aleevlkekklqleeafiekviqlyellkvrhgvmlvGetgsGKt 327 +++++ + +l+ + f++k+iqlye++ vrhg+mlvG+tgsGKt FUN_001547-T1 1768 SIRKTCLKLGLEDVNGFVTKCIQLYETTVVRHGLMLVGPTGSGKT 1812 ********************************************8 PP == domain 2 score: -3.6 bits; conditional E-value: 6 AAA_6 312 vrhgvmlvGetgsGKt 327 ++ v++vG+tgsGKt FUN_001547-T1 2161 NNKKVLCVGPTGSGKT 2176 4567889999999997 PP == domain 3 score: 1.4 bits; conditional E-value: 0.18 AAA_6 187 kLakklvtlyklaseql...skqkhYdfglralksvlktagsl...kraepeeseeklllralrdvnlpklvaeDvplfkglisd 265 +L + +++y+ + ql ++hY f+lr l v + + k ++ ++ + + +r ++ + +eD + f +li+d FUN_001547-T1 2342 SLVRNTIAVYNTVITQLlptPAKSHYTFNLRDLSKVFQGILMAeaqKLSDLSDVLRLWYHENCRVFQDRLVNDEDRKWFVDLIRD 2426 566777888888888874444799***********98755444100332222222222233444444444445688888888877 PP >> DHC_N2 Dynein heavy chain, N-terminal region 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.6 0.87 8.5e+02 252 304 .. 783 837 .. 772 838 .. 0.76 2 ? -3.2 0.4 4 4e+03 243 300 .. 883 937 .. 866 947 .. 0.59 3 ! 517.4 6.3 3.4e-158 3.3e-155 3 403 .] 960 1361 .. 958 1361 .. 0.98 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.87 DHC_N2 252 krFkkvdkefkkimkkaskdpn.vleatekpg.llekleelneqLekiqksLney 304 k+ + v +efk i + ++++pn + e+ e+++ +++ e+l+++ e i k++ +y FUN_001547-T1 783 KQADMVCEEFKAIARVLYDKPNsIEELSEQREyMKQIPEKLKKNQELIDKAMVDY 837 56678899*************8455555555457777888888888888888777 PP == domain 2 score: -3.2 bits; conditional E-value: 4 DHC_N2 243 irkqlpeeakrFkkvdkefkkimkkaskdpnvleatekpgllekleelneqLekiqks 300 +k+l +++ F++ + + + +++++++ + ++ +++++l +qL+++q FUN_001547-T1 883 FQKNLLADQNTFQDRLDSLNMAVAGFAAHTDISK---AHEVANEVRRLTKQLKECQTL 937 4555555555555555555555555555555555...334666666666666666654 PP == domain 3 score: 517.4 bits; conditional E-value: 3.4e-158 DHC_N2 3 elekeleplkklwdlvsewqekleewketpfkeldveeleeeveellkklkklpkelke....wevaeelkkkieefkkslplleelknpalke 92 +l k++ep+k++w ++s+w + +++w++ p++++d+e+le++v++ +k++ k+ k++ke +eva e+k+kie+fk+++pl++ l+np+++ FUN_001547-T1 960 RLIKDFEPFKNMWLTASDWMKWYDSWMNDPLTTIDAEQLEQNVNNAFKTVFKCVKHFKEipacQEVAMEVKEKIENFKPYIPLIQGLRNPGMRS 1053 6889*******************************************************99999999999************************ PP DHC_N2 93 rHWkqlseilgkelkdpdseedltlgdllelglekfeeeieeiseqAskElaiekalkkieeewkelefelepykdtgvfilkgvdelielled 186 rHW+qls+ lg+++ + +lt+ ++le++l++++e i++++e A kE++ie+al+k+e+ewk + +e+ pyk+tg+fi+k d+ +ll+d FUN_001547-T1 1054 RHWEQLSNDLGFPIV---ANAQLTFTKCLEMKLQDHIEVIAKVAEVAGKEYSIEQALDKMESEWKPVMLEVLPYKETGTFIMKVSDDCSQLLDD 1144 **********96555...5667************************************************************************ PP DHC_N2 187 hlvklqsmkaspyvkpfeeeveewekkLsliqevldewlkvQrkWlyLepiFssedirkqlpeeakrFkkvdkefkkimkkaskdpnvleatek 280 h+v+ qsm++spy kpfee+++ we+kL +q+v+dewl++Qr+WlyLepiFssedi++qlp e+kr++++++ ++k+m+ a+ +p+v++++ + FUN_001547-T1 1145 HIVMAQSMSFSPYKKPFEERITTWESKLVMTQDVMDEWLQCQRQWLYLEPIFSSEDINRQLPVESKRYQTMERIWRKVMNSAKGNPQVISLCPD 1238 ********************************************************************************************** PP DHC_N2 281 pgllekleelneqLekiqksLneyLekkRlaFpRFyFlsndeLLeiLsqskdptavqphlkklFegikslefeenkeitgmiskegEkvplskk 374 p+ll++l+e+n++Le++qk+L+eyLe+kR+aFpRFyFls+deLLeiLsq+kdptavqphl+k+Fe+i++l+fee+ +i +m+s egE vp+s+k FUN_001547-T1 1239 PRLLDSLRECNKLLEQVQKGLSEYLETKRTAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIAKLSFEEDLRISSMFSGEGECVPFSNK 1332 *******************************************************************************************999 PP DHC_N2 375 vkakgnveeWLneveeemkeslrellkea 403 + +gnve+WL eve++m+ slre+l++a FUN_001547-T1 1333 LYPSGNVEDWLLEVENTMRGSLREILNKA 1361 999**********************9875 PP >> Dynein_C Dynein heavy chain C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.6 8.1 7.9e+03 28 128 .. 765 864 .. 754 868 .. 0.72 2 ? -4.0 0.2 9.4 9.2e+03 75 116 .. 1413 1455 .. 1411 1457 .. 0.75 3 ! 417.8 0.0 3.7e-128 3.6e-125 1 309 [] 3890 4192 .. 3890 4192 .. 0.95 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 8.1 Dynein_C 28 sreevvlelakeileklpeefdie..kaeekypveyeeplntvllqEierfnkLlkeirrsLkelqkalkGevvmseeleelansllnnkvPesWa 121 +r+ +++++ + +kl ++ d+ + ++ +v y +p ++ E++ ++ +k+i ++Lk+ q+ ++ +v e +ee s+ + ++W+ FUN_001547-T1 765 KRKALANAVIELLAKKLRKQADMVceEFKAIARVLYDKPNSI---EELSEQREYMKQIPEKLKKNQELIDKAMVDYELIEEFNYSISAEDFNAKWT 857 455556666666667777766666422333367777777766...788888888899999999999999999999999999999999999999997 PP Dynein_C 122 kksypsl 128 +p + FUN_001547-T1 858 CIGWPHK 864 7788776 PP == domain 2 score: -4.0 bits; conditional E-value: 9.4 Dynein_C 75 rfnkLlkeirrsLkelqkalkGev.vmseeleelansllnnkv 116 +++ L++ +r +L++l++++ G + v+ + +++ +++ +kv FUN_001547-T1 1413 QLSDLVTLVRGNLSKLSRMILGALiVIEVHACDVVAKMISEKV 1455 56789***************99751555566667766666665 PP == domain 3 score: 417.8 bits; conditional E-value: 3.7e-128 Dynein_C 1 tneteellstllslqprsssgssggsksreevvlelakeileklpeefdiekaeekypveyeeplntvllqEierfnkLlkeirrsLkelqkal 94 +net +ll+ +l++qprss++ + ++sreev++e + ilek+p+++ i + ek+pv+yee++ntvl+qE++r+nkLl+++r++L++l kal FUN_001547-T1 3890 QNETFSLLQGILKMQPRSSTS--A-GRSREEVMEEAGRGILEKVPQPIPIAMVIEKHPVRYEESMNTVLIQEVIRYNKLLETVRQTLNDLLKAL 3980 689**************6522..3.4899*****************999999999*************************************** PP Dynein_C 95 kGevvmseeleelansllnnkvPesWakksypslkplgsWikdllkRveqlqkwleeegePkvfwLsgfffpqaFLtavlqnyarknkiplDkl 188 kG+vvms+ le++ans++nn vPe Wa+k+ypslkpl+sW++dl++Rv+++++w+ e+g P vfw+sgfffpq+FLt++lqnyar+++i++D + FUN_001547-T1 3981 KGLVVMSQALETMANSIFNNSVPELWASKAYPSLKPLASWVTDLVARVQFIENWI-EHGIPPVFWISGFFFPQGFLTGTLQNYARSSSISIDVI 4073 *******************************************************.889*********************************** PP Dynein_C 189 slefevtkkeeeeevkekpedGvyvkGLfLeGArwdrkkgkLeesepkelfselPvihlkpveakkkkkekkkyecPvYktseRrgvlsttghs 282 +++fev+kk +e+e +++p++G++++GLfLeGArwd +k+ L+es+pkel++++P+i+lkp+ +++k + k yecPvYkt +R+g+lsttghs FUN_001547-T1 4074 TFDFEVMKK-TEAELTSRPSNGCFIRGLFLEGARWDFDKHELTESRPKELYTDMPIIWLKPTANREKPD-KGIYECPVYKTLTRAGTLSTTGHS 4165 *******87.66889**********************************************86555544.777********************* PP Dynein_C 283 tnfvfsvdLptkkppehwilrGvAlll 309 tnfv+ v++p+++p++hwi+rGvAl++ FUN_001547-T1 4166 TNFVLPVEIPSSQPQRHWIKRGVALMC 4192 *************************98 PP >> AAA_8 P-loop containing dynein motor region D4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.9 1.3 1.3e+03 184 225 .. 979 1021 .. 970 1038 .. 0.72 2 ? -3.4 0.1 6.5 6.4e+03 183 221 .. 1370 1408 .. 1364 1421 .. 0.69 3 ! 330.4 0.0 9.3e-102 9.1e-99 1 259 [] 2488 2748 .. 2488 2748 .. 0.99 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1.3 AAA_8 184 idwfeeWPeeaLeevatkvled.leieeelkeelvkvfvevhs 225 ++w++ W ++ L + + le+ ++++ ++ ++vk+f+e+ FUN_001547-T1 979 MKWYDSWMNDPLTTIDAEQLEQnVNNAFKTVFKCVKHFKEIPA 1021 78******************88444444555577777776644 PP == domain 2 score: -3.4 bits; conditional E-value: 6.5 AAA_8 183 tidwfeeWPeeaLeevatkvledleieeelkeelvkvfv 221 +w+ +WP + + + + +++ e+ +++++ ++ + FUN_001547-T1 1370 RTEWVLQWPGQIVIAGCQTHWTKEVSEALVENKIEELYK 1408 679********9999888888775555555555554444 PP == domain 3 score: 330.4 bits; conditional E-value: 9.3e-102 AAA_8 1 ldLvlfkealehllrilRvlsqprgnlLlvglgGsGrqsltkLaaliaelelfeievtkkydvkefredlkkvlkkagikkkevvfllsdkqiv 94 ++Lvlf +a++h++ri+Rv++qp gn+Ll+g+gGsGrqslt+Laa++ae+e+f+ie++k+y+v e+redlkk+l k g+++k++vfl+sd+qi+ FUN_001547-T1 2488 MKLVLFGDAVRHVARISRVIRQPLGNALLLGVGGSGRQSLTRLAAHMAEYECFQIELAKNYGVPEWREDLKKILLKSGVENKSMVFLFSDTQIK 2581 89******************************************************************************************** PP AAA_8 95 kesfledinnllnsGevpnlfskeekeeiieevrkeakaqnieeskeevfnlfvkrvrenLhivlsmspvgeafrkrlrkfpsLvscctidwfe 188 +esfled+nn+ln G+vpn+f ++e ++i+++++ + +++++k+++++ f+krvr n h v++msp+ge fr+rlr+fpsLv+cctidwf+ FUN_001547-T1 2582 SESFLEDLNNVLNAGDVPNIFAQDELDTIFTAMKPVVLDLGMQPTKANLYSAFTKRVRANTHSVVCMSPIGEIFRARLRQFPSLVNCCTIDWFS 2675 ********************************************************************************************** PP AAA_8 189 eWPeeaLeevatkvled..leieeelkeelvkvfvevhssveklskkfleelkrknyvtpksyLellklykkL 259 +WPeeaL++va+ +l + + ++ + e lv+++ +h+sv+ sk++l+el+r+nyvtp+syLell +++kL FUN_001547-T1 2676 AWPEEALRSVASTFLGEipELEDSPAMEGLVSICGVIHQSVSLKSKQYLAELSRHNYVTPTSYLELLGTFRKL 2748 *****************87778888999******************************************987 PP >> AAA_9 ATP-binding dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.5 1.5e+03 174 217 .. 1242 1290 .. 1239 1293 .. 0.73 2 ! 305.1 0.1 2.6e-94 2.6e-91 1 222 [] 3135 3356 .. 3135 3356 .. 0.98 3 ? 4.3 0.0 0.027 26 32 122 .. 3614 3695 .. 3595 3713 .. 0.77 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.5 AAA_9 174 lkeeaenkkklkeledklLeeLsesegni.....LedeelietLeesKk 217 l + e +k l+++++ l e L++++ + L d+el+e L+++K FUN_001547-T1 1242 LDSLRECNKLLEQVQKGLSEYLETKRTAFprfyfLSDDELLEILSQTKD 1290 5566677778888888888888777775333344*************96 PP == domain 2 score: 305.1 bits; conditional E-value: 2.6e-94 AAA_9 1 reWnlegLpsDelsieNaiiltkssrwplliDPqgqankwiknmeken.lkvislsdkkflktlenairfGkpvLiedvgeeldpiLepvLeke 93 r+W+++gLp+D+ls+eN++i++ ++rwpl+iDPqgqankwik+ ek+ l vi+lsd++fl++lena+rfGkp+L+e+vgeeldp+Lep+L k+ FUN_001547-T1 3135 RNWQIAGLPRDTLSVENGVIVQFTQRWPLFIDPQGQANKWIKSLEKDAgLDVIKLSDRDFLRSLENAVRFGKPCLLENVGEELDPALEPILLKQ 3228 68******************************************88888********************************************* PP AAA_9 94 iikkkggrkliklgdkevdyspnFrLylttklsnphyspevsakvtlinFtvteegLedqlLaivvkkerpeleekreellkeeaenkkklkel 187 ++k++g +++iklgd + y+++F++y+ttkl+nphy+pevs+kvt++nFt+++ gLedqlLa vv++erp+lee +++l++++a++k++lke+ FUN_001547-T1 3229 TFKQSG-STVIKLGDAIIPYHDDFKFYITTKLPNPHYTPEVSTKVTIVNFTLSPGGLEDQLLALVVAEERPDLEEAKNQLIVSNAKMKQELKEI 3321 ***866.*************************************************************************************** PP AAA_9 188 edklLeeLsesegniLedeelietLeesKktseei 222 edk+L++Ls seg+ ++d +li+tLe+sK++s ei FUN_001547-T1 3322 EDKILHKLSASEGSPVDDIDLIHTLEQSKAKSMEI 3356 ********************************998 PP == domain 3 score: 4.3 bits; conditional E-value: 0.027 AAA_9 32 DPqgqankwiknm.ekenlkvisls...dkkflktlenairfGkpvLiedvgeeldpiLepvLekeiikkkggrkliklgdkevdyspnFrLyl 121 DP k+ ++m +++l+ isl ++ + +a++ Gk v+++++ +l p++ p Le+ + + + dk ++++FrL l FUN_001547-T1 3614 DPAADLYKFAEEMrFTKKLNAISLGqgqGPRAEAMMRSAMERGKWVFFQNC--HLAPSFMPALERLVENI-D-------PDK---VHRDFRLWL 3694 999999999999966666999999866556788899***************..9*********9977763.2.......133...566666666 PP AAA_9 122 t 122 t FUN_001547-T1 3695 T 3695 4 PP >> AAA_7 P-loop containing dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.029 28 39 76 .. 1523 1557 .. 1505 1565 .. 0.88 2 ? 6.0 0.2 0.011 11 33 57 .. 1798 1822 .. 1786 1828 .. 0.79 3 ! 255.6 0.0 2.8e-79 2.7e-76 2 180 .. 2131 2310 .. 2130 2311 .. 0.97 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.029 AAA_7 39 vGptGtGKtviikdllkkldkekylsltinfsaqttan 76 Gp+GtGKt ++kdl k++ ++++++n+s q + + FUN_001547-T1 1523 AGPAGTGKTETTKDLGKAMA---VQCVVFNCSDQLDFM 1557 59***************999...888889999887655 PP == domain 2 score: 6.0 bits; conditional E-value: 0.011 AAA_7 33 kkpvLlvGptGtGKtviikdllkkl 57 ++ ++lvGptG+GKt + + l k+l FUN_001547-T1 1798 RHGLMLVGPTGSGKTRCYEVLKKAL 1822 6779***********9887665555 PP == domain 3 score: 255.6 bits; conditional E-value: 2.8e-79 AAA_7 2 kidedvpfseilVptvdtvrysyllelllknkkpvLlvGptGtGKtviikd.llkkldkekylsltinfsaqttanqlqeiiesklekrrkgvy 94 +i+++++fs+i++pt+d vr s++le+ll n+k+vL+vGptG+GKt+++ + ll+ ++ +++ls+++nfsa+t+anq+q+ii+skl+krrkgv+ FUN_001547-T1 2131 TIPPEMNFSDIIIPTMDLVRGSFVLEMLLINNKKVLCVGPTGSGKTLCVANkLLNYMP-KEFLSHFLNFSARTSANQTQDIIDSKLDKRRKGVF 2223 5899***********************************************6666666.*********************************** PP AAA_7 95 gPpggkklvvFvDDlnmpakdkygaqppiellRqlldyggwYdrkkl.efkeikdvqlvaamgppgggrneitpRllrhfnvlaite 180 gPp gk++v+FvDDlnmpa + ygaqppie+lRq++d++gwYdrk + +f+e++d+++v+amgppgggrn++tpR+lrhfn l++te FUN_001547-T1 2224 GPPLGKHFVFFVDDLNMPALEVYGAQPPIEILRQYCDHKGWYDRKAIgTFRELVDINFVSAMGPPGGGRNPVTPRFLRHFNHLSFTE 2310 *********************************************988***********************************9986 PP >> MT Microtubule-binding stalk of dynein motor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 181.1 9.7 4.2e-56 4.1e-53 2 338 .. 2762 3106 .. 2761 3111 .. 0.94 Alignments for each domain: == domain 1 score: 181.1 bits; conditional E-value: 4.2e-56 MT 2 rlengllklqstaaqvddlkaklaiqevelkqknedadkliqvvgveaekvskekaiadeeevkvevinkevkekqkdceedlakaepallaaq 95 r + gl kl sta +v+ l+ l + l q e++ + ++ + v++ k + ++ee + e + d + dl a pal aa FUN_001547-T1 2762 RTKVGLDKLLSTADEVEKLQEELETMQPLLAQAAEETVETMEKIKVDSVVANETKVVVQREEEEAAKKAAETQAIADDAQRDLDEALPALEAAL 2855 67789*****************************************99999999**************************************** PP MT 96 ealdtlnktnltelksfgsppdavvnvsaavmvltaprgk......vpk..dkswkaakvtmakvdtfldslkkfdkeniheaclkaikpylqd 181 ++l++lnkt++ e++++ pp v v av ++ + k v d w k ++ fl+ l k+dk+ni++++++ i+py ++ FUN_001547-T1 2856 ASLKSLNKTDVVEVRALQRPPPGVKLVIEAVSIMKGVKAKkvagekVGTkvDDYWEPGKALLQDPGKFLEGLFKYDKDNIPDTVIQKIQPYIEN 2949 *******************************99876543211111143223889**************************************** PP MT 182 pefdpefvaskstaaaglcswvinivrfyevycdvepkrqalekataelaeaqeklaaikakiaelnenlakltaafekataeklkcqqeaevt 275 +f+p +a s a++ +c wv + +++ v v+pkr al++at el e+q la ka++a+++e +a l a++e + a+k + ++e FUN_001547-T1 2950 EDFQPAAIAKVSKACTSICQWVRAMHKYHFVSKAVAPKRAALKQATEELQETQRVLAEAKARLADVEEGIASLQAKYEECIAKKQELEFKTEQC 3043 ********************************************************************************************** PP MT 276 avvillanrlvgglasenvrwaeavenfksqevtlcgdvllisafvsylgyftkkyrqellek 338 + + a++l+ggl+ e+vrw e+v +f q v ++gdv++ s ++ylg ft yr +++e FUN_001547-T1 3044 SARLGRAEKLIGGLSDEKVRWHESVLEFDAQIVNIVGDVMISSGVIAYLGTFTGEYRVSMVEE 3106 ***********************************************************9986 PP >> AAA_lid_11 Dynein heavy chain AAA lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 174.7 0.0 1.6e-54 1.5e-51 2 140 .] 3746 3884 .. 3745 3884 .. 0.96 Alignments for each domain: == domain 1 score: 174.7 bits; conditional E-value: 1.6e-54 AAA_lid_11 2 kkllfsLcffhavvqeRrkfgplGwnipYeFnesDlrisvkvlknlleeyeekvpwealryligeinYGGrvtddwDrrllktlleeffneevl 95 k llfsLc+fh v +eRrkfg+lG+nipYeF+++Dlri++++l+++leeye vp++ l+y++g+inYGGrvtddwDrr+++++l++f++++vl FUN_001547-T1 3746 KFLLFSLCLFHGVTLERRKFGALGFNIPYEFTTGDLRICISQLNMFLEEYEG-VPFKVLKYTAGHINYGGRVTDDWDRRCIMNILNDFYSPAVL 3838 679***********************************************55.***************************************** PP AAA_lid_11 96 eedyklsesgly.kipeeksleeyleyieslpledspevfglhena 140 ++++k+s+sg+y ++p ++++e+yl+yi+ lp++d+pe+f+lh+na FUN_001547-T1 3839 SDEHKFSDSGIYhQLPLTSDHEHYLRYIRGLPINDTPEIFALHDNA 3884 ***********725556999*************************8 PP >> Dynein_heavy Dynein heavy chain region D6 P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 158.2 0.0 9.5e-50 9.4e-47 2 115 .] 3601 3714 .. 3600 3714 .. 0.99 Alignments for each domain: == domain 1 score: 158.2 bits; conditional E-value: 9.5e-50 Dynein_heavy 2 attPlifilspgaDptaeleklakkkklkkklksislGqgqeekAeklieeaakeGeWvlLqNchlalswlpeLekileelkeeklhedfRlwl 95 ++tPlif+ls g+Dp+a+l k+a++++++kkl++islGqgq+++Ae+++++a+++G+Wv++qNchla+s++p Le+++e+++ +k+h+dfRlwl FUN_001547-T1 3601 TNTPLIFVLSVGTDPAADLYKFAEEMRFTKKLNAISLGQGQGPRAEAMMRSAMERGKWVFFQNCHLAPSFMPALERLVENIDPDKVHRDFRLWL 3694 689******************************************************************************************* PP Dynein_heavy 96 tsepspkfPvsiLqnsiklt 115 ts+pspkfPvsiLqn+ k+t FUN_001547-T1 3695 TSMPSPKFPVSILQNGSKMT 3714 *******************8 PP >> Dynein_AAA_lid Dynein heavy chain AAA lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 111.3 0.0 4.5e-35 4.4e-32 1 115 [. 1980 2098 .. 1980 2103 .. 0.94 Alignments for each domain: == domain 1 score: 111.3 bits; conditional E-value: 4.5e-35 Dynein_AAA_lid 1 leelfeklvdpalefvrknckeivptsdlnlvqslcrlleallkelleenek..eeleeeklkklleklflfalvWsiggsldedsrkkfdef 91 l++lf+++++++l+fvrkn ke+vpt+++nl sl+r+le+++++++ ++++ +++ + +++l+e +f+fal+Ws+gg++d d+rkkf+ef FUN_001547-T1 1980 LQSLFDRFLEDSLKFVRKNTKEFVPTVNSNLTCSLMRILECFFAPFVPKEGEtiLDENIALIETLIEPWFIFALIWSVGGTCDGDGRKKFSEF 2072 799***********************************************999999999********************************** PP Dynein_AAA_lid 92 lrells..klklPfpeegtvyDyfvd 115 lr+ ++ ++k+ fp++g vyDy ++ FUN_001547-T1 2073 LRKKMDdeQIKMKFPKHGLVYDYSLE 2098 ****99995555566********876 PP >> AAA_5 AAA domain (dynein-related subfamily) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.0 0.0015 1.5 6 139 .] 1524 1644 .. 1523 1644 .. 0.72 2 ! 31.7 0.0 1.8e-10 1.8e-07 2 139 .] 1801 1946 .. 1800 1946 .. 0.91 3 ! 15.5 0.0 1.8e-05 0.018 2 139 .] 2165 2303 .. 2164 2303 .. 0.85 4 ? 2.5 0.0 0.19 1.9e+02 2 35 .. 2514 2546 .. 2513 2558 .. 0.86 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0015 AAA_5 6 GppGtgKselaerlaaalenrsvlyvqltrdtteedlvgrreiangttelvdgplvraar.egeilvlDEinraesevlnsLlsllderrllle 98 Gp GtgK+e ++ l +a+ + ++ ++++ +l g++ + g+ +++DE+nr++ evl ++ + +++ + le FUN_001547-T1 1524 GPAGTGKTETTKDLGKAM-AVQCVVFNCSD-----QLDFMAM----------GKFFKGLAsAGAWACFDEFNRIDVEVLSVVAQQISTIQQALE 1601 666777777777777777.33333334433.....3322222..........3333222248999*******************9999999999 PP AAA_5 99 eggelvkvapdd.llkk.frliatanpldrglnelspalrsRf 139 + + ++ + +l++ ++ t+np + g+ el +l+ f FUN_001547-T1 1602 ARVDRFMFEGVElALRPsCAVFITMNPGYAGRTELPDNLKALF 1644 999999888877656558***********99999999998776 PP == domain 2 score: 31.7 bits; conditional E-value: 1.8e-10 AAA_5 2 vlLvGppGtgKselaerlaaale.............nrsvlyvqltrdtteedlvgrreiangttelvdgplvraar.........egeilvlD 73 ++LvGp+G+gK++ e l++al+ ++ + v++++++t +l g++++ t e++dg l +r +++ ++++ FUN_001547-T1 1801 LMLVGPTGSGKTRCYEVLKKALTslkgkdspsgspyEQVHTFVLNPKSITMGQLYGEFDL--LTHEWTDGILSSMIRvgssstnsdKKWYVFDG 1892 89******************************99988888999****************8..***********9999********888888888 PP AAA_5 74 EinraesevlnsLlsllderrllleeggelvkvapddllkkfrliatanpldrglnelspalrsRf 139 ++ +++ ++++ld+++ l +ge +k ++ ++ +++ +l +spa++sR+ FUN_001547-T1 1893 PVD---AVWIENMNTVLDDNKKLCLTSGEIIKLSEA-----MTMMFEVQDLA----VASPATVSRC 1946 899...*************************99885.....66666666655....8889988885 PP == domain 3 score: 15.5 bits; conditional E-value: 1.8e-05 AAA_5 2 vlLvGppGtgKse.laerlaaalenrsv..lyvqltrdtteedlvgrreiangttelvdgplvraaregeilvlDEinraesevlnsLlsllde 92 vl vGp+G+gK+ +a +l+ + +++ + +++++t++++ + ++ ++ ++++g++ + ++++D++n+ ev ++ ++++ FUN_001547-T1 2165 VLCVGPTGSGKTLcVANKLLNYM-PKEFlsHFLNFSARTSANQTQDIID--SKLDKRRKGVFGPPLGKHFVFFVDDLNMPALEVYGAQ-PPIEI 2254 7889********83556777777.555511678999*************..7999999*****************************9.88888 PP AAA_5 93 rrllleeggelvkvapddllkk..frliatanpldrglnelspalrsRf 139 r + + g++ ++a ++ + ++++ ++ p+ +g+n + p++++ f FUN_001547-T1 2255 LRQYCDHKGWYDRKAIGTFRELvdINFVSAMGPPGGGRNPVTPRFLRHF 2303 888889999999998765544478*******************999876 PP == domain 4 score: 2.5 bits; conditional E-value: 0.19 AAA_5 2 vlLvGppGtgKselaerlaaalenrsvlyvqltr 35 lL+G G+g+ +l++ a++ +++ + + l + FUN_001547-T1 2514 ALLLGVGGSGRQSLTRLAAHMA-EYECFQIELAK 2546 59******************99.88777776665 PP >> AAA_lid_1 AAA+ lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 7.2 7.1e+03 5 32 .. 1670 1701 .. 1668 1707 .. 0.66 2 ! 64.1 0.1 1.7e-20 1.7e-17 1 81 [. 2343 2423 .. 2343 2443 .. 0.88 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 7.2 AAA_lid_1 5 alalhqkiaatflpta....ikfhyvfnlrdl 32 a al +ki++tf ++ + hy f +r + FUN_001547-T1 1670 AKALAKKITTTFKLSSeqlsSQDHYDFGMRAV 1701 67999*******75541111345777777765 PP == domain 2 score: 64.1 bits; conditional E-value: 1.7e-20 AAA_lid_1 1 lvdlalalhqkiaatflptaikfhyvfnlrdlanifqgllfssvevlkstldlvrlylheservyrdkmveekdfelldkv 81 lv ++a+++ + + +lpt k hy fnlrdl+++fqg+l++ ++ l d++rl+ he rv++d++v++ d + + + FUN_001547-T1 2343 LVRNTIAVYNTVITQLLPTPAKSHYTFNLRDLSKVFQGILMAEAQKLSDLSDVLRLWYHENCRVFQDRLVNDEDRKWFVDL 2423 5778899******************************************************************99877554 PP >> DYN_lid Dynein heavy chain, ATPase lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 2.5 2.4e+03 15 59 .. 1669 1711 .. 1661 1728 .. 0.76 2 ! 61.9 0.1 8e-20 7.8e-17 13 93 .] 2337 2417 .. 2323 2417 .. 0.89 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 2.5 DYN_lid 15 kaealakamvelYeevkkkFtaddqshYifspreLTrwvrgllea 59 +a+alak + ++ ++++++ +q hY f +r + ++ + + FUN_001547-T1 1669 EAKALAKKITTTFKLSSEQLS--SQDHYDFGMRAVKTVISAAGNL 1711 678899999999999999998..799*****99987777665555 PP == domain 2 score: 61.9 bits; conditional E-value: 8e-20 DYN_lid 13 kskaealakamvelYeevkkkF.taddqshYifspreLTrwvrglleaikdlesesleellrlwayealrlFrDrLvseeek 93 ++ +++l++ ++++Y++v +++ + +shY+f+ r+L+++++g+l a + ++ ++l+++lrlw++e +r+F+DrLv++e++ FUN_001547-T1 2337 ETLCDSLVRNTIAVYNTVITQLlPTPAKSHYTFNLRDLSKVFQGILMA-EAQKLSDLSDVLRLWYHENCRVFQDRLVNDEDR 2417 4578999**********8877626679*********************.888889************************986 PP >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.0 0.0003 0.29 15 89 .. 1799 1885 .. 1788 1913 .. 0.73 2 ! 13.8 0.0 5e-05 0.049 12 39 .. 2159 2187 .. 2153 2211 .. 0.82 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0003 xxxxxxxxxxxxxxxxxxxx..xxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx..xxxxxxxxxx RF DEAD 15 kdvlvqapTGsGKTlafllp..ilealk.......kkkegpqalvlaPtreLaeqiveelkkllkk.lglkvasl..lggdsrkeql 89 + +++++pTGsGKT ++ + +l +lk + e+ ++vl P + q + e+ l+++ ++ ++s+ +g++s+++++ FUN_001547-T1 1799 HGLMLVGPTGSGKTRCYEVLkkALTSLKgkdspsgSPYEQVHTFVLNPKSITMGQLYGEFDLLTHEwTDGILSSMirVGSSSTNSDK 1885 66899***********97642266666478888887888899999999999999999999888886655344333125555554444 PP == domain 2 score: 13.8 bits; conditional E-value: 5e-05 x.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF DEAD 12 l.egkdvlvqapTGsGKTlafllpileal 39 l ++k+vl+++pTGsGKTl+ + +l+ + FUN_001547-T1 2159 LiNNKKVLCVGPTGSGKTLCVANKLLNYM 2187 44899***************998888766 PP >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.0 0.00063 0.62 23 81 .. 1798 1866 .. 1770 1898 .. 0.79 2 ! 13.1 0.0 9.3e-05 0.091 22 62 .. 2161 2201 .. 2147 2219 .. 0.85 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00063 ResIII 23 ekrglivmaTGsGKTlvaakliarlskkgkek..........kvlflvdrkeLleqakeefkkflseek 81 ++ +++v +TGsGKT+++ l ++l++ + ++ ++++l ++ + q++ ef +++e + FUN_001547-T1 1798 RHGLMLVGPTGSGKTRCYEVLKKALTSLKGKDspsgspyeqvHTFVLNPKSITMGQLYGEFDLLTHEWT 1866 56778*************999888888766667889999998888888888888899999988777654 PP == domain 2 score: 13.1 bits; conditional E-value: 9.3e-05 ResIII 22 gekrglivmaTGsGKTlvaakliarlskkgkekkvlflvdr 62 ++k++l v +TGsGKTl+ a+ +++ k+ +++l + r FUN_001547-T1 2161 NNKKVLCVGPTGSGKTLCVANKLLNYMPKEFLSHFLNFSAR 2201 7899***********************99888888866555 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.0 0.0015 1.4 5 35 .. 1524 1554 .. 1523 1607 .. 0.87 2 ? 3.4 0.1 0.14 1.4e+02 1 22 [. 1801 1822 .. 1801 1858 .. 0.83 3 ? 5.4 0.0 0.035 34 1 35 [. 2165 2204 .. 2165 2242 .. 0.56 4 ? 2.0 0.0 0.38 3.7e+02 2 38 .. 2515 2574 .. 2514 2649 .. 0.66 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.0015 AAA 5 GppGtGKTllakavakelgaefveisgselv 35 Gp GtGKT + k + k++ +++v +++s+ + FUN_001547-T1 1524 GPAGTGKTETTKDLGKAMAVQCVVFNCSDQL 1554 9***************************987 PP == domain 2 score: 3.4 bits; conditional E-value: 0.14 AAA 1 lllyGppGtGKTllakavakel 22 l+l+Gp G GKT + + + k+l FUN_001547-T1 1801 LMLVGPTGSGKTRCYEVLKKAL 1822 589*********9988877665 PP == domain 3 score: 5.4 bits; conditional E-value: 0.035 AAA 1 lllyGppGtGKTll.akavakelg....aefveisgselv 35 +l +Gp G GKTl+ a+ + + + +f+++s+ FUN_001547-T1 2165 VLCVGPTGSGKTLCvANKLLNYMPkeflSHFLNFSARTSA 2204 6889********9724567777652333444444444444 PP == domain 4 score: 2.0 bits; conditional E-value: 0.38 AAA 2 llyGppGtGKTllakavakelgaefveisgselvsk.......................y 38 ll G G G+ +l + a+ +++e+++i++ + + FUN_001547-T1 2515 LLLGVGGSGRQSLTRLAAHMAEYECFQIELAKNYGVpewredlkkillksgvenksmvfL 2574 899999******************999999998833445555555555444444444441 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.087 86 12 43 .. 1524 1552 .. 1521 1570 .. 0.85 2 ! 9.7 0.0 0.0014 1.4 8 35 .. 1801 1837 .. 1798 1874 .. 0.73 3 ! 8.8 0.0 0.0028 2.7 8 47 .. 2165 2204 .. 2161 2231 .. 0.73 4 ? 0.5 0.0 0.99 9.8e+02 8 96 .. 2514 2610 .. 2508 2624 .. 0.84 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.087 AAA_22 12 GesGtGKTtllrrlleqldeeddsvvlvelps 43 G++GtGKT + + l + +++v +++++ FUN_001547-T1 1524 GPAGTGKTETTKDLGKAM---AVQCVVFNCSD 1552 9*************9998...78888888876 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0014 AAA_22 8 lvltGesGtGKTtllrrlleqldee.........dds 35 l+l+G++G+GKT++++ l++ l++ + + FUN_001547-T1 1801 LMLVGPTGSGKTRCYEVLKKALTSLkgkdspsgsPYE 1837 689***************9999766777776666333 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0028 AAA_22 8 lvltGesGtGKTtllrrlleqldeeddsvv..lvelpsstsp 47 ++++G++G+GKT+++++ l ++ +++++ + + ++ ts+ FUN_001547-T1 2165 VLCVGPTGSGKTLCVANKLLNYM--PKEFLshFLNFSARTSA 2204 689***********998887775..55555545555555544 PP == domain 4 score: 0.5 bits; conditional E-value: 0.99 AAA_22 8 lvltGesGtGKTtllrrlleqldeeddsvvlvelpsst...spkdllrellralglelek........elskeellaalqealkalaaravlii 90 +l G G+G+ l r ++ + + +++ +el++ ++++ l+++l + g+e+++ + +e +l+ l++ l+a +++ ++ FUN_001547-T1 2514 ALLLGVGGSGRQSLTRLAAHMA---EYECFQIELAKNYgvpEWREDLKKILLKSGVENKSmvflfsdtQIKSESFLEDLNNVLNAGDVPNIFAQ 2604 6788888999999999999998...88888777777766789**************9999*****99777788888***999999999999999 PP AAA_22 91 DEaqnl 96 DE + + FUN_001547-T1 2605 DELDTI 2610 998875 PP >> Mg_chelatase Magnesium chelatase, subunit ChlI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.0 0.00072 0.7 19 53 .. 1795 1829 .. 1778 1848 .. 0.82 2 ! 8.0 0.0 0.0024 2.3 15 65 .. 2155 2206 .. 2149 2219 .. 0.81 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00072 Mg_chelatase 19 aaGgHnlllvGppGsGKtmlakrlpsllpplseee 53 +H l+lvGp GsGKt + l++ l++l+ ++ FUN_001547-T1 1795 TVVRHGLMLVGPTGSGKTRCYEVLKKALTSLKGKD 1829 5568*****************99999999988766 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0024 Mg_chelatase 15 leiaaaGgHnlllvGppGsGKtm.lakrlpsllpplseeealevakiksvag 65 le+ + + ++l vGp GsGKt+ +a++l + +p+ + l+ ++ +s ++ FUN_001547-T1 2155 LEMLLINNKKVLCVGPTGSGKTLcVANKLLNYMPKEFLSHFLNFSARTSANQ 2206 56666678899***********857999******999999999998888877 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.36 3.6e+02 31 51 .. 1524 1544 .. 1523 1619 .. 0.79 2 ! 8.8 0.0 0.003 3 25 68 .. 1799 1836 .. 1790 1876 .. 0.78 3 ! 7.2 0.0 0.0096 9.4 27 62 .. 2165 2198 .. 2161 2220 .. 0.78 4 ? 0.7 0.0 0.93 9.1e+02 18 75 .. 2505 2557 .. 2495 2623 .. 0.67 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.36 AAA_16 31 GeaGvGKSalvrellralera 51 G+aG+GK+ ++ l +a + + FUN_001547-T1 1524 GPAGTGKTETTKDLGKAMAVQ 1544 9**********9999887766 PP == domain 2 score: 8.8 bits; conditional E-value: 0.003 AAA_16 25 plvlvsGeaGvGKSalvrellraleraalvlsgkcdelqrglpy 68 + ++++G++G+GK++ + l +al+ l gk +g py FUN_001547-T1 1799 HGLMLVGPTGSGKTRCYEVLKKALTS----LKGKDSP--SGSPY 1836 4689*************988876654....3444333..35555 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0096 AAA_16 27 vlvsGeaGvGKSalv.rellraleraalvlsgkcdel 62 vl++G++G+GK+ v ++ll+ +++ + +++ ++ FUN_001547-T1 2165 VLCVGPTGSGKTLCVaNKLLNYMPKE---FLSHFLNF 2198 89*************99999999998...44444444 PP == domain 4 score: 0.7 bits; conditional E-value: 0.93 AAA_16 18 rvrsgrp.plvlvsGeaGvGKSalvrellraleraalvlsgkcdelqrglpy.aa.lleal 75 rv ++ p ++ l+ G G+G +l+r +++ +e + c +++ + y ++ + e l FUN_001547-T1 2505 RVIRQ-PlGNALLLGVGGSGRQSLTRLAAHMAEYE-------CFQIELAKNYgVPeWREDL 2557 44444.4499**************99999655555.......4444333334334466665 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 7.2 7e+03 24 43 .. 1524 1543 .. 1523 1555 .. 0.75 2 ? 2.7 0.0 0.13 1.3e+02 18 41 .. 1799 1822 .. 1785 1840 .. 0.82 3 ! 9.1 0.0 0.0014 1.4 13 48 .. 2158 2195 .. 2154 2237 .. 0.72 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 7.2 nSTAND3 24 GepGiGKttlaemLalklld 43 G+ G+GKt + + L +++ FUN_001547-T1 1524 GPAGTGKTETTKDLGKAMAV 1543 99******999988777665 PP == domain 2 score: 2.7 bits; conditional E-value: 0.13 nSTAND3 18 kvviitGepGiGKttlaemLalkl 41 + ++++G++G+GKt + e L +l FUN_001547-T1 1799 HGLMLVGPTGSGKTRCYEVLKKAL 1822 66899*********9988886555 PP == domain 3 score: 9.1 bits; conditional E-value: 0.0014 nSTAND3 13 iLeknkvviitGepGiGKttlaemLalklldegy..ev 48 +L +nk v+ +G++G+GKt + + +l+++ +++ ++ FUN_001547-T1 2158 LLINNKKVLCVGPTGSGKTLCVANKLLNYMPKEFlsHF 2195 478999**************999888888888764333 PP >> T2SSE Type II/IV secretion system protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.1 4.1 4e+03 258 302 .. 762 806 .. 760 834 .. 0.67 2 ! 7.2 0.1 0.0024 2.3 132 164 .. 1789 1823 .. 1768 1830 .. 0.64 3 ! 6.2 0.0 0.0048 4.8 126 160 .. 2146 2180 .. 2121 2192 .. 0.69 4 ? -1.0 0.0 0.77 7.6e+02 120 156 .. 2489 2525 .. 2482 2538 .. 0.79 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 4.1 T2SSE 258 lgveafelasslavviaQrLvrklcpscke......slldekaklarpvgc 302 l+ +++ la+++ ++a++L ++++ c+e +p++ FUN_001547-T1 762 LAKKRKALANAVIELLAKKLRKQADMVCEEfkaiarV------LYDKPNSI 806 667788999999999*****99999999994333320......22333333 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0024 T2SSE 132 kellralkqprglilvtGpTGsGKttt...Lyalle 164 +l ++ ++gl+lv GpTGsGKt L+++l+ FUN_001547-T1 1789 IQLYETTVVRHGLMLV-GPTGSGKTRCyevLKKALT 1823 4566666778999998.********75111444444 PP == domain 3 score: 6.2 bits; conditional E-value: 0.0048 T2SSE 126 leeeqkkellralkqprglilvtGpTGsGKtttLy 160 ++ + +l++l + +l GpTGsGKt FUN_001547-T1 2146 MDLVRGSFVLEMLLINNKKVLCVGPTGSGKTLCVA 2180 55555666778888888899***********8653 PP == domain 4 score: -1.0 bits; conditional E-value: 0.77 T2SSE 120 eleklgleeeqkkellralkqprglilvtGpTGsGKt 156 +l g ++ ++++r+++qp g+ l+ G GsG+ FUN_001547-T1 2489 KLVLFGDAVRHVARISRVIRQPLGNALLLGVGGSGRQ 2525 55556666677899*********************85 PP >> RNA_helicase RNA helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.031 31 5 64 .. 1524 1584 .. 1522 1602 .. 0.66 2 ? 5.0 0.0 0.049 48 2 26 .. 1802 1825 .. 1801 1879 .. 0.82 3 ? 2.0 0.0 0.42 4.1e+02 2 26 .. 2166 2191 .. 2165 2213 .. 0.66 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.031 RNA_helicase 5 GpsgeGKStlakelakallkklklpkkdsvysrnpeddfwdgYk.gqevviidDfgqvkde 64 Gp+g+GK+ ++k+l ka++ + + + ++ ++ +f++g + ++d+f+++ e FUN_001547-T1 1524 GPAGTGKTETTKDLGKAMAVQCVVFNCSDQLDFMAMGKFFKGLAsAGAWACFDEFNRIDVE 1584 9*****************9776333333333345677777777755566677777776655 PP == domain 2 score: 5.0 bits; conditional E-value: 0.049 RNA_helicase 2 wlyGpsgeGKStlakelakallkkl 26 +l+Gp+g GK+++ + l kal++ l FUN_001547-T1 1802 MLVGPTGSGKTRCYEVLKKALTS-L 1825 799*************9999883.2 PP == domain 3 score: 2.0 bits; conditional E-value: 0.42 RNA_helicase 2 wlyGpsgeGKStlake.lakallkkl 26 + +Gp+g GK++++ + l + + k++ FUN_001547-T1 2166 LCVGPTGSGKTLCVANkLLNYMPKEF 2191 679********986551555554444 PP >> AAA_30 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 0.036 35 24 43 .. 1523 1542 .. 1520 1555 .. 0.87 2 ? 5.5 0.0 0.018 18 22 46 .. 1802 1827 .. 1792 1859 .. 0.84 3 ? -0.9 0.0 1.6 1.6e+03 20 35 .. 2164 2179 .. 2154 2183 .. 0.77 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.036 AAA_30 24 vGpAGtGKTtalkalreawe 43 GpAGtGKT + k l +a++ FUN_001547-T1 1523 AGPAGTGKTETTKDLGKAMA 1542 59*********999988876 PP == domain 2 score: 5.5 bits; conditional E-value: 0.018 AAA_30 22 vlvGpAGtGKTtalkalreaweaa.g 46 +lvGp G+GKT ++l++a+++ g FUN_001547-T1 1802 MLVGPTGSGKTRCYEVLKKALTSLkG 1827 799*****************998744 PP == domain 3 score: -0.9 bits; conditional E-value: 1.6 AAA_30 20 vqvlvGpAGtGKTtal 35 + vGp G+GKT + FUN_001547-T1 2164 KVLCVGPTGSGKTLCV 2179 46789********765 PP >> AAA_18 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.003 2.9 4 67 .. 1523 1597 .. 1523 1619 .. 0.66 2 ? 2.9 0.0 0.21 2.1e+02 2 22 .. 1802 1822 .. 1801 1849 .. 0.83 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.003 AAA_18 4 tGtpGvGKttlareLserlgf.......gdnvrdlakenglvlsddee....tdeskrldedklaklldeleela 67 +G+ G+GKt++++ L +++ + +d + ++a + + ++ de++r+d ++l+++ +++ + FUN_001547-T1 1523 AGPAGTGKTETTKDLGKAMAVqcvvfncSDQLDFMAMGKFFKGLASAGawacFDEFNRIDVEVLSVVAQQISTIQ 1597 69***************9866768555533333333333333333333555567777777777777777776665 PP == domain 2 score: 2.9 bits; conditional E-value: 0.21 AAA_18 2 litGtpGvGKttlareLserl 22 +++G+ G+GKt + L+++l FUN_001547-T1 1802 MLVGPTGSGKTRCYEVLKKAL 1822 689**************9987 PP >> AAA_19 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.1 0.25 2.5e+02 18 36 .. 1524 1542 .. 1521 1553 .. 0.83 2 ? 3.6 0.0 0.097 96 9 40 .. 1796 1827 .. 1790 1844 .. 0.81 3 ? 2.0 0.0 0.31 3.1e+02 9 31 .. 2160 2182 .. 2156 2205 .. 0.84 4 ? -1.7 0.3 4.3 4.2e+03 30 82 .. 2966 3023 .. 2961 3047 .. 0.67 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.25 AAA_19 18 gGpGtGKTtvikaivellk 36 g +GtGKT ++k + + ++ FUN_001547-T1 1524 GPAGTGKTETTKDLGKAMA 1542 889********98877665 PP == domain 2 score: 3.6 bits; conditional E-value: 0.097 AAA_19 9 lkekvvlltgGpGtGKTtvikaivellkelke 40 + ++ ++l+g G+GKT++ + + + l +lk+ FUN_001547-T1 1796 VVRHGLMLVGPTGSGKTRCYEVLKKALTSLKG 1827 556668899*********99988888877765 PP == domain 3 score: 2.0 bits; conditional E-value: 0.31 AAA_19 9 lkekvvlltgGpGtGKTtvikai 31 +++k vl +g G+GKT ++ FUN_001547-T1 2160 INNKKVLCVGPTGSGKTLCVANK 2182 678889999********998765 PP == domain 4 score: -1.7 bits; conditional E-value: 4.3 AAA_19 30 aivellkelkee.aeillvaptgrAakrlaeatgle....akTihrllefddlevefe 82 i+++++++++ + +vap + A k+ +e++++ a+ +rl ++++ +++++ FUN_001547-T1 2966 SICQWVRAMHKYhFVSKAVAPKRAALKQATEELQETqrvlAEAKARLADVEEGIASLQ 3023 5677777777665777888998888888888774443455777777777766664443 PP >> AAA_33 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 7.7 7.6e+03 6 24 .. 1524 1542 .. 1523 1560 .. 0.83 2 ? 4.3 0.1 0.066 65 2 20 .. 1801 1819 .. 1801 1825 .. 0.83 3 ? 3.6 0.0 0.11 1.1e+02 2 18 .. 2165 2181 .. 2165 2194 .. 0.77 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 7.7 AAA_33 6 GlsGsGKstlarrlleelg 24 G+ G+GK+ + l ++ + FUN_001547-T1 1524 GPAGTGKTETTKDLGKAMA 1542 9*******99998877665 PP == domain 2 score: 4.3 bits; conditional E-value: 0.066 AAA_33 2 illvGlsGsGKstlarrll 20 ++lvG+ GsGK+ ++ l FUN_001547-T1 1801 LMLVGPTGSGKTRCYEVLK 1819 589*********9988665 PP == domain 3 score: 3.6 bits; conditional E-value: 0.11 AAA_33 2 illvGlsGsGKstlarr 18 +l+vG+ GsGK+ +++ FUN_001547-T1 2165 VLCVGPTGSGKTLCVAN 2181 689*********88776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (4196 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1891 (0.0740262); expected 510.9 (0.02) Passed bias filter: 1115 (0.0436485); expected 510.9 (0.02) Passed Vit filter: 109 (0.00426698); expected 25.5 (0.001) Passed Fwd filter: 47 (0.00183989); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 26 [number of targets reported over threshold] # CPU time: 1.22u 0.40s 00:00:01.62 Elapsed: 00:00:00.45 # Mc/sec: 37490.33 // Query: FUN_001548-T1 [L=140] Description: FUN_001548 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-31 107.4 0.8 6.8e-31 107.0 0.1 1.5 2 CENP-S CENP-S protein 8.2e-07 29.6 0.2 1.3e-06 29.0 0.2 1.4 1 CENP-T_C Centromere kinetochore component CENP-T histone 0.0016 18.9 0.1 0.0025 18.3 0.1 1.3 1 Bromo_TP Bromodomain associated 0.005 17.1 1.9 0.0054 17.0 1.9 1.1 1 BCCIP BCCIP ------ inclusion threshold ------ 0.019 15.8 1.7 0.031 15.1 0.1 1.9 2 Histone Core histone H2A/H2B/H3/H4 domain 0.028 15.0 0.2 0.039 14.5 0.2 1.3 1 TFIID-31kDa Transcription initiation factor IID, 31kD subuni 0.092 13.3 4.5 0.12 12.9 3.7 1.5 1 ZapG-like Z-ring associated protein G-like Domain annotation for each model (and alignments): >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.0 0.1 1.9e-34 6.8e-31 1 76 [] 20 95 .. 20 95 .. 0.98 2 ? -2.4 0.1 2.5 9e+03 25 61 .. 121 127 .. 106 134 .. 0.52 Alignments for each domain: == domain 1 score: 107.0 bits; conditional E-value: 1.9e-34 CENP-S 1 erLKaalwysvgkiveeealeekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRstittdDvlLlaRrnesL 76 +rLKaal+++vg+i+e++ +e+++++++qfiaalte+++kq+e++a+DLe+FAkHAkRs+++ dDvlLl+R++++L FUN_001548-T1 20 QRLKAALHFTVGRICENTGKETGLQFSRQFIAALTETTFKQCESFATDLELFAKHAKRSQVNCDDVLLLSRKSSAL 95 79**********************************************************************9876 PP == domain 2 score: -2.4 bits; conditional E-value: 2.5 CENP-S 25 evtpqfiaaltelvykqlenlakDLeaFAkHAkRsti 61 + Ak s+i FUN_001548-T1 121 K------------------------------AKNSKI 127 2..............................333333 PP >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 0.2 3.6e-10 1.3e-06 27 84 .. 41 98 .. 25 122 .. 0.83 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 3.6e-10 CENP-T_C 27 skaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrkitkk 84 + + s++ ++al++++ + e + DLe +akHA+R +++ +DvllL ++ + ++ FUN_001548-T1 41 TGLQFSRQFIAALTETTFKQCESFATDLELFAKHAKRSQVNCDDVLLLSRKSSALATH 98 4467899999**************************************9988776654 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 6.8e-07 0.0025 11 65 .. 29 86 .. 19 89 .. 0.81 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 6.8e-07 Bromo_TP 11 vvsqileeaGfd...saeesaLetLteiaqkYirelgeqaksfaehagRseptlkDvv 65 v i+e+ G + ++ + +Lte++ k +++++ + + fa ha Rs+++ Dv FUN_001548-T1 29 TVGRICENTGKEtglQFSRQFIAALTETTFKQCESFATDLELFAKHAKRSQVNCDDVL 86 56666666665533347788999*********************************96 PP >> BCCIP BCCIP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 1.9 1.5e-06 0.0054 109 195 .. 36 133 .. 8 140 .] 0.71 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 1.5e-06 BCCIP 109 skkkkvgLllseRliNmPvevvpplykmLleeieaakede.kepykfkhylilskvykeveskedee..........erkkkkkkkkkkkkkkeee 193 ++ k++gL +s +i +e + + ++ ++e + ++ +++++++ +l+ls+ + +++++e+ e+++kk+kk+k++k ++++ FUN_001548-T1 36 NTGKETGLQFSRQFIAALTETTFKQCESFATDLELFAKHAkRSQVNCDDVLLLSRKSSALATHMEEKskeliqaheeEKANKKQKKAKNSKISNAD 131 55578999999999999999999999********998666799**************999988888899999986532334444433333333444 PP BCCIP 194 el 195 + FUN_001548-T1 132 TV 133 44 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.1 8.6e-06 0.031 24 85 .. 29 88 .. 10 91 .. 0.82 2 ? -0.2 0.2 0.52 1.9e+03 64 78 .. 114 128 .. 99 134 .. 0.63 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 8.6e-06 Histone 24 pfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlA 85 + R++ + ++++l +s++ + al+e++ ++++++ +l akhaKR+ ++ +D+ l FUN_001548-T1 29 TVGRICENT--GKETGLQFSRQFIAALTETTFKQCESFATDLELFAKHAKRSQVNCDDVLLL 88 556644444..4599***************************************99999875 PP == domain 2 score: -0.2 bits; conditional E-value: 0.52 Histone 64 eAnllakhaKRvTlt 78 +An+ k+aK++ + FUN_001548-T1 114 KANKKQKKAKNSKIS 128 344444455555444 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.2 1.1e-05 0.039 23 90 .. 45 113 .. 36 134 .. 0.78 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.1e-05 TFIID-31kDa 23 yeprVvlqLlefayrYttevledAkvysehakkkkidlddvrl.AiqsrveksftepppkelLlelAre 90 ++ + + L e +++ + +d +++++hak++++++ddv l + +s + + e+ +kel++ +e FUN_001548-T1 45 FSRQFIAALTETTFKQCESFATDLELFAKHAKRSQVNCDDVLLlSRKSSALATHMEEKSKELIQAHEEE 113 67788999********************************97614445555555566677777665554 PP >> ZapG-like Z-ring associated protein G-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 3.7 3.4e-05 0.12 62 103 .. 89 131 .. 83 139 .. 0.84 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 3.4e-05 ZapG-like 62 akdyqkLyqhlaksseeLlp.eltekdlpvkskleekkkdkek 103 ++ ++L++h++++s+eL+ +++ek + +++k +++k ++++ FUN_001548-T1 89 SRKSSALATHMEEKSKELIQaHEEEKANKKQKKAKNSKISNAD 131 667789*************989999999999999998877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (140 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2962 (0.115952); expected 510.9 (0.02) Passed bias filter: 761 (0.0297906); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1415.70 // Query: FUN_001549-T1 [L=266] Description: FUN_001549 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-34 117.6 12.1 9.2e-34 116.1 12.1 1.8 1 Ribosomal_L44 Ribosomal protein L44 8.9e-24 84.4 2.2 9e-24 84.4 0.2 2.0 2 CFAP90 Cilia and flagella associated protein 90 Domain annotation for each model (and alignments): >> Ribosomal_L44 Ribosomal protein L44 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 116.1 12.1 7.2e-38 9.2e-34 1 76 [] 179 254 .. 179 254 .. 0.99 Alignments for each domain: == domain 1 score: 116.1 bits; conditional E-value: 7.2e-38 Ribosomal_L44 1 kHtehkVeqykkgkaselaqgqRrydrkqkgygGqtkpvlkrkaKttKKvvlrleCteCkkkhlkelkRakkfelv 76 kHt hkV+qyk+gkas +aqg+RrydrkqkgygGqtkpv+++kaKttKK+vlrleCt Ck++++ +lkR+k+fel+ FUN_001549-T1 179 KHTLHKVSQYKAGKASLYAQGKRRYDRKQKGYGGQTKPVFRKKAKTTKKIVLRLECTVCKYRKQLPLKRCKHFELG 254 8*************************************************************************96 PP >> CFAP90 Cilia and flagella associated protein 90 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.4 0.2 7e-28 9e-24 1 80 [. 82 161 .. 82 171 .. 0.95 2 ? -1.6 0.1 0.48 6.2e+03 24 36 .. 195 207 .. 170 213 .. 0.64 Alignments for each domain: == domain 1 score: 84.4 bits; conditional E-value: 7e-28 CFAP90 1 sYFnnekkekrvslYDrlfkvkegydsklhRdDrehaksiglnineeekekpvpvlsssvYGrrlrkpldeperkfvrva 80 sYF + +++ s+YDr+ +v egy++ lhRdDrehaks+gl++n+ee + vp lsss YG++ kpl+ ++rk+vrv+ FUN_001549-T1 82 SYFRAKTLHSKPSAYDRINHVVEGYNQNLHRDDREHAKSRGLTVNSEEIRVSVPSLSSSLYGHPRLKPLELTDRKHVRVE 161 79*9999999********************************************************************95 PP == domain 2 score: -1.6 bits; conditional E-value: 0.48 CFAP90 24 gydsklhRdDreh 36 y + + R Dr++ FUN_001549-T1 195 LYAQGKRRYDRKQ 207 4666666777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (266 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1160 (0.0454101); expected 510.9 (0.02) Passed bias filter: 609 (0.0238403); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.34s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 2728.12 // Query: FUN_001550-T1 [L=260] Description: FUN_001550 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-43 146.4 0.5 4.1e-23 82.0 0.6 2.1 2 NIPSNAP NIPSNAP ------ inclusion threshold ------ 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 Glucokinase Glucokinase Domain annotation for each model (and alignments): >> NIPSNAP NIPSNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.0 0.6 3.2e-27 4.1e-23 1 100 [. 51 148 .. 51 149 .. 0.97 2 ! 62.4 0.0 4.1e-21 5.2e-17 1 102 [] 161 258 .. 161 258 .. 0.99 Alignments for each domain: == domain 1 score: 82.0 bits; conditional E-value: 3.2e-27 NIPSNAP 1 yelrtYrlkpgklaeflenferaigarqakcgseliGyftseiGelnqvvhlwayaslaerearRaalaadpew.eatvkeavelkfieemesril 95 ye+rtY++kp+ a+f++ +++i+ + ++s+l Gy+ts+iG +n+v+h+w y+s+a+r+++R+al +d+ w + ++k+ ++ + ++++ ++ FUN_001550-T1 51 YEMRTYYVKPKAFADFMKLTNEYIHLKSE-SNSKLNGYWTSDIGGTNEVIHIWEYDSFAQRTEARKALSQDQTWiNSYIKKILKM--LTKQDNLVM 143 9**********************999999.********************************************99999999999..********* PP NIPSNAP 96 lptsf 100 +++++ FUN_001550-T1 144 YAVPW 148 **998 PP == domain 2 score: 62.4 bits; conditional E-value: 4.1e-21 NIPSNAP 1 yelrtYrlkpgklaeflenferaigarqakcgseliGyftseiGelnqvvhlwayaslaerearRaalaadpeweatvkeavelkfieemesrill 96 yelr Y++ gk +++ + ++ r + se+ G++t+e+G+l+ +v lw y+sl+er + R+++ + +ew ++v+ + + s++l+ FUN_001550-T1 161 YELRMYDIMLGKGEQWQHRLIQGFPDRCK--VSEPAGVWTTEFGPLSAAVFLWPYPSLDERIRIRKEAQQLEEWVEAVRDCSSF--AKGGVSKVLI 252 9****************************..****************************************************9..********** PP NIPSNAP 97 ptsfSp 102 pt+fSp FUN_001550-T1 253 PTDFSP 258 *****8 PP >> Glucokinase Glucokinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 1.8e-05 0.23 3 50 .. 90 136 .. 88 157 .. 0.84 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 1.8e-05 Glucokinase 3 gDiGGTnarlalveaeeeeeleeietyasadyasleeavqkylaeeae 50 DiGGTn ++++e+++ ++ +e+++ s+d + +++ ++k+l+ + FUN_001550-T1 90 SDIGGTNEVIHIWEYDSFAQRTEARKALSQDQTWINSYIKKILKM-LT 136 7******************9*********************9984.22 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (260 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1212 (0.0474457); expected 510.9 (0.02) Passed bias filter: 888 (0.0347622); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2556.19 // Query: FUN_001551-T1 [L=340] Description: FUN_001551 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-07 31.2 0.1 1.7e-05 25.5 0.1 2.3 2 RWD RWD domain 5e-05 23.9 2.9 7.6e-05 23.4 1.9 1.9 1 zf-rbx1 RING-H2 zinc finger domain 7.3e-05 23.4 0.5 7.3e-05 23.4 0.5 2.6 2 zf-RING_2 Ring finger domain 0.00029 21.1 4.9 0.00029 21.1 4.9 2.4 2 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 0.0017 18.8 4.5 0.0029 18.1 0.5 2.3 2 zf-ANAPC11 Anaphase-promoting complex subunit 11 RI ------ inclusion threshold ------ 0.023 14.8 0.3 0.023 14.8 0.3 2.2 2 Zn_ribbon_11 Probable zinc-ribbon 0.023 15.1 0.8 0.023 15.1 0.8 2.5 2 zf-RING_5 zinc-RING finger domain 0.025 14.8 0.4 0.085 13.1 0.4 2.0 1 zf-RING_11 RING-like zinc finger 0.049 14.3 1.2 0.049 14.3 1.2 2.1 1 zf-RING-like RING-like domain 0.058 13.7 1.2 0.058 13.7 1.2 2.7 2 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 0.063 13.9 0.0 0.12 12.9 0.0 1.4 1 DUF3276 Protein of unknown function (DUF3276) 0.083 13.9 0.1 0.2 12.7 0.1 1.6 1 GDH_ACT2 Glutamate dehydrogenase, ACT2 domain 0.083 12.7 0.3 0.23 11.3 0.3 1.7 1 zf_RING_Vps8_fungal Vps8 RING zinc finger, fungal 0.11 13.0 4.5 0.34 11.4 3.4 2.4 1 zf-RING_UBOX RING-type zinc-finger 0.32 11.1 2.6 4.8 7.3 0.5 2.3 2 ZnF_RZ-type RZ type zinc finger domain 1.7 8.8 6.2 1.2 9.3 3.1 2.4 2 zf-RING_Vps41 Vps41 C-terminal RING finger domain 3.1 8.1 11.8 0.39 11.0 0.7 2.5 2 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) Domain annotation for each model (and alignments): >> RWD RWD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.1 1.1e-08 1.7e-05 4 111 .. 14 112 .. 11 113 .. 0.85 2 ? 3.6 0.0 0.066 99 33 93 .. 149 200 .. 118 208 .. 0.67 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.1e-08 xxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF RWD 4 eeEleaLesIypdefevis...dseyekkleieiklslksdeseesklvslvlevtlpedYPdepPkislsskenlsreqvssllekleelaeenl 96 ++Ele+ + I +++e + + ++++++ + k s+ + +++pe+YP+ + +++l+sk ++ + + ++++ ++++a+++ FUN_001551-T1 14 DKELEIVKKILNEKVEGSElisCHPLA----VNVRITRT-------KFKSVIVLLQFPEKYPADAIVVELKSKT-IPPSLLVKMTRLCDQEAKTLA 97 68*************666632133333....77777777.......5789************************.********************9 PP xxxxxxxxxxxxxxx RF RWD 97 gevmifeliewlqen 111 g + + ++++ + FUN_001551-T1 98 GKSQVIPMLSFVRRF 112 999999999888765 PP == domain 2 score: 3.6 bits; conditional E-value: 0.066 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF RWD 33 eiklslksdeseesklvslvlevtlpedYPdepPkislsskenlsreqvssllekleelae 93 +i+ +++++ l+++vt+p+dY +++ +++++++ +++ v+ + + ++a FUN_001551-T1 149 NIRA--------NQDQYFLDVKVTVPDDYYTAAVRVEMKESN-FPENLVKVFVGRAVDMAR 200 2222........4557789**********9999999999999.888877776666665555 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 1.9 5.1e-08 7.6e-05 2 55 .] 241 300 .. 240 300 .. 0.78 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 5.1e-08 zf-rbx1 2 tCaiCrneleeacieckapgdee.cpvvwGeCgHaFHlhCiskWlkt.....rntCPlcr 55 C +C+++ ++ +++++ v C+H FH+ C++k++kt ++CP c+ FUN_001551-T1 241 LCPVCKQKALPDNPKDIVSDSSDqKFVERVYCNHLFHYGCLDKYMKTppftgGKKCPSCK 300 6999999877666655544444435666678*******************9999***995 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 2.2 0.43 6.5e+02 28 44 .] 232 246 .. 216 253 .. 0.67 2 ! 23.4 0.5 4.8e-08 7.3e-05 16 44 .] 267 300 .. 258 300 .. 0.83 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.43 zf-RING_2 28 eCldkwlrtsst..CPlCr 44 eC++ ++ CP+C+ FUN_001551-T1 232 ECVRP----CPRelCPVCK 246 44433....3344488885 PP == domain 2 score: 23.4 bits; conditional E-value: 4.8e-08 zf-RING_2 16 vivlpCgHvfhkeCldkwlrtsst.....CPlCr 44 v ++ C+H fh+ Cldk+++t + CP C+ FUN_001551-T1 267 VERVYCNHLFHYGCLDKYMKTPPFtggkkCPSCK 300 55778*************99999999999****6 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 2.3 0.76 1.1e+03 12 40 .] 233 245 .. 224 256 .. 0.56 2 ! 21.1 4.9 1.9e-07 0.00029 1 40 [] 242 299 .. 242 299 .. 0.84 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 0.76 zf-C3HC4 12 vtllpCgHsfCssCiksllesnnvkCplC 40 + + pC ++ Cp+C FUN_001551-T1 233 C-VRPCPREL---------------CPVC 245 3.34444444...............4444 PP == domain 2 score: 21.1 bits; conditional E-value: 1.9e-07 zf-C3HC4 1 CpiCleelkepv..............tllpCgHsfCssCikslle....snnvkCplC 40 Cp+C++++ + + + + C+H f++ C++++++ ++++kCp C FUN_001551-T1 242 CPVCKQKALPDNpkdivsdssdqkfvERVYCNHLFHYGCLDKYMKtppfTGGKKCPSC 299 88888765544445777888888888899********************99999**** PP >> zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.3 0.23 3.4e+02 51 60 .. 239 248 .. 228 252 .. 0.85 2 ! 18.1 0.5 2e-06 0.0029 31 62 .. 271 304 .. 261 307 .. 0.83 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.23 zf-ANAPC11 51 kglcPmcrqt 60 ++lcP+c+q+ FUN_001551-T1 239 RELCPVCKQK 248 689****997 PP == domain 2 score: 18.1 bits; conditional E-value: 2e-06 zf-ANAPC11 31 kckhsfhlhcilkWlete..tskglcPmcrqtfk 62 c+h fh c+ k+++t+ t ++cP c+q ++ FUN_001551-T1 271 YCNHLFHYGCLDKYMKTPpfTGGKKCPSCKQRIY 304 5****************83344569******876 PP >> Zn_ribbon_11 Probable zinc-ribbon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.3 1.2 1.8e+03 20 26 .. 241 247 .. 240 248 .. 0.81 2 ? 14.8 0.3 1.5e-05 0.023 15 30 .. 290 305 .. 288 310 .. 0.88 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.2 Zn_ribbon_11 20 hCpaCgt 26 +Cp C++ FUN_001551-T1 241 LCPVCKQ 247 6999997 PP == domain 2 score: 14.8 bits; conditional E-value: 1.5e-05 Zn_ribbon_11 15 YeGeKhCpaCgtgIYS 30 ++G K Cp+C++ IY FUN_001551-T1 290 FTGGKKCPSCKQRIYH 305 89*************5 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 4.4 0.11 1.7e+02 27 43 .] 232 247 .. 224 247 .. 0.86 2 ? 15.1 0.8 1.5e-05 0.023 19 43 .] 271 301 .. 260 301 .. 0.92 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.11 zf-RING_5 27 eClkklleerqCpiCkk 43 eC+ + ++ Cp+Ck+ FUN_001551-T1 232 ECVRPCP-RELCPVCKQ 247 8999999.*******96 PP == domain 2 score: 15.1 bits; conditional E-value: 1.5e-05 zf-RING_5 19 sCgHifCeeClkkll......eerqCpiCkk 43 C H+f+ Cl+k++ ++Cp Ck+ FUN_001551-T1 271 YCNHLFHYGCLDKYMktppftGGKKCPSCKQ 301 5****************************96 PP >> zf-RING_11 RING-like zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.4 5.7e-05 0.085 19 29 .] 271 281 .. 261 281 .. 0.82 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 5.7e-05 zf-RING_11 19 pCsHvFHykCi 29 C+H FHy C+ FUN_001551-T1 271 YCNHLFHYGCL 281 6*********6 PP >> zf-RING-like RING-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 1.2 3.2e-05 0.049 18 43 .] 271 299 .. 268 300 .. 0.84 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 3.2e-05 zf-RING-like 18 dCnvrlHkdClekyfrtrrs...kkCpkC 43 Cn +H+ Cl+ky++t kkCp+C FUN_001551-T1 271 YCNHLFHYGCLDKYMKTPPFtggKKCPSC 299 7***************9544445*****9 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 1.8 0.44 6.6e+02 15 31 .. 234 250 .. 224 255 .. 0.58 2 ? 13.7 1.2 3.9e-05 0.058 17 40 .] 271 299 .. 263 299 .. 0.82 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.44 zf-C3HC4_2 15 vtpCgHvfCqkCilraL 31 v pC C C +aL FUN_001551-T1 234 VRPCPRELCPVCKQKAL 250 55565566666655555 PP == domain 2 score: 13.7 bits; conditional E-value: 3.9e-05 zf-C3HC4_2 17 pCgHvfCqkCilraLee.....sneCPlC 40 C H f++ C++++++ +++CP C FUN_001551-T1 271 YCNHLFHYGCLDKYMKTppftgGKKCPSC 299 6*************98644443679**99 PP >> DUF3276 Protein of unknown function (DUF3276) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 8.2e-05 0.12 16 39 .. 149 172 .. 136 186 .. 0.87 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 8.2e-05 DUF3276 16 vlraGrRtYflDvrktkaddyylt 39 +ra + YflDv+ t ddyy + FUN_001551-T1 149 NIRANQDQYFLDVKVTVPDDYYTA 172 599*******************86 PP >> GDH_ACT2 Glutamate dehydrogenase, ACT2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 0.00014 0.2 4 58 .. 150 209 .. 148 211 .. 0.80 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.00014 GDH_ACT2 4 lRrdeygrfvsclvyvPrdrYntelrlkiqei.....Laealegeevefttylsesvlar 58 +R ++ + f+ + v vP d Y++++r +++e L + + g+ v++ ++ e +l r FUN_001551-T1 150 IRANQDQYFLDVKVTVPDDYYTAAVRVEMKESnfpenLVKVFVGRAVDMARQCVEAPLRR 209 677777789******************998633333388999999999999988888877 PP >> zf_RING_Vps8_fungal Vps8 RING zinc finger, fungal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.3 0.00015 0.23 18 28 .. 272 282 .. 260 285 .. 0.92 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00015 zf_RING_Vps8_fungal 18 CrHgFHkkCLe 28 C+H FH+ CL+ FUN_001551-T1 272 CNHLFHYGCLD 282 **********6 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 3.4 0.00023 0.34 1 39 [] 242 297 .. 242 297 .. 0.70 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00023 zf-RING_UBOX 1 CpICleeft............dPlvlp.......CGHtfCreCl..welskkekgkikCP 39 Cp+C++ d + C H f+ Cl ++++ +g kCP FUN_001551-T1 242 CPVCKQKALpdnpkdivsdssD----QkfvervyCNHLFHYGCLdkYMKTPPFTGGKKCP 297 9999997778855544444441....04444444**********9877888888888888 PP >> ZnF_RZ-type RZ type zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.5 0.0032 4.8 20 40 .. 228 248 .. 227 249 .. 0.93 2 ? 3.3 0.1 0.059 88 32 41 .. 294 303 .. 290 310 .. 0.88 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0032 ZnF_RZ-type 20 yvigeCGrameesrCpeCgat 40 ++i eC r+ + Cp C+++ FUN_001551-T1 228 FLISECVRPCPRELCPVCKQK 248 89****************975 PP == domain 2 score: 3.3 bits; conditional E-value: 0.059 ZnF_RZ-type 32 srCpeCgatI 41 +Cp C+++I FUN_001551-T1 294 KKCPSCKQRI 303 69*****998 PP >> zf-RING_Vps41 Vps41 C-terminal RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 2 3e+03 14 24 .. 47 56 .. 35 57 .. 0.68 2 ? 9.3 3.1 0.00079 1.2 3 41 .. 242 287 .. 240 301 .. 0.64 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 2 zf-RING_Vps41 14 gqaklfsivvF 24 +k+ s++v+ FUN_001551-T1 47 R-TKFKSVIVL 56 2.89****997 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00079 zf-RING_Vps41 3 CslCfdpilisgq.......aklfsivvFkCgHifHktClmsells 41 C +C + l+ + + + C H fH Cl + + FUN_001551-T1 242 CPVCKQKALPDNPkdivsdsSDQKFVERVYCNHLFHYGCLDKYMKT 287 666666666655544444443444577899**********987765 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 4.6 0.35 5.2e+02 28 45 .. 232 248 .. 226 250 .. 0.81 2 ? 11.0 0.7 0.00026 0.39 19 46 .. 271 303 .. 262 305 .. 0.90 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.35 zf-C3HC4_3 28 eCaeklrkkkkCpiCrqk 45 eC + + ++ Cp+C+qk FUN_001551-T1 232 ECVRPC-PRELCPVCKQK 248 577777.7788****997 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00026 zf-C3HC4_3 19 pCgHlclCeeCaeklr......kkkkCpiCrqki 46 C+Hl + + C +k++ kkCp C+q i FUN_001551-T1 271 YCNHL-FHYGCLDKYMktppftGGKKCPSCKQRI 303 6****.99********9****99*********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (340 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 854 (0.0334312); expected 510.9 (0.02) Passed bias filter: 630 (0.0246624); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3283.25 // Query: FUN_001552-T1 [L=1196] Description: FUN_001552 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-27 94.9 2.2 1.4e-26 93.5 2.2 1.8 1 F5_F8_type_C F5/8 type C domain 6.3e-06 27.2 1.6 3e-05 25.0 1.6 2.2 1 F5_F8_type_C_2 NedA-like, galactose-binding domain 7.4e-05 22.7 0.0 0.0051 16.9 0.0 2.7 2 EF-hand_6 EF-hand domain 0.0006 20.6 0.6 0.0039 18.0 0.0 2.5 2 EF-hand_7 EF-hand domain pair ------ inclusion threshold ------ 0.034 14.2 0.1 0.16 12.1 0.0 2.2 2 EF-hand_1 EF hand domain Domain annotation for each model (and alignments): >> F5_F8_type_C F5/8 type C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.5 2.2 2.8e-30 1.4e-26 3 127 .] 562 701 .. 560 701 .. 0.91 Alignments for each domain: == domain 1 score: 93.5 bits; conditional E-value: 2.8e-30 F5_F8_type_C 3 tasssesgeg.paaaald....GnkntaWssssnddkqwlqvdLgkekkitgvvlqgrqdgg........ngrvksykieysddgenWtevkd... 82 ass ++ + p +a+l+ G+k++aW +++nd kq+lqvdLg++ +t+v +qg + + + +v sy++ +s++g++W+++ + FUN_001552-T1 562 RASSVYDRYHmPSEARLNktkqGKKAGAWKPKTNDTKQYLQVDLGAVSSVTQVSTQGFPTVSgekvqkkeKCWVESYTLAFSTNGSQWHQYDEndv 657 68999777779*******999999999*****************************9876555556667799*********************877 PP F5_F8_type_C 83 ekv.kgnsdnstpvtntfdkpvkaryvrlvptswnggngialraEl 127 kv kgn dn+++v+n++++p+karyvr+ p+sw+++ ialr+E+ FUN_001552-T1 658 VKVfKGNRDNNSVVINSLPNPIKARYVRFIPQSWKNS--IALRVEV 701 6669******************************999..****996 PP >> F5_F8_type_C_2 NedA-like, galactose-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 1.6 5.8e-09 3e-05 5 90 .] 584 686 .. 581 686 .. 0.78 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 5.8e-09 F5_F8_type_C_2 5 Gntntrwhta.nedpqwlqvDLgssytissvvltnegd...........ccgerlkgykiqvsddg......snwttvatvt.ngpggntetitf 80 G+++ w + n+++q+lqvDLg++ ++++v + c +++y++ s++g +++ v+ + n+++++++ ++ FUN_001552-T1 584 GKKAGAWKPKtNDTKQYLQVDLGAVSSVTQVSTQGFPTvsgekvqkkekC---WVESYTLAFSTNGsqwhqyDENDVVKVFKgNRDNNSVVINSL 675 6677789999788********************98888889999885433...4578*********55555433344444455666677778888 PP F5_F8_type_C_2 81 .navtaryvrv 90 n+++aryvr+ FUN_001552-T1 676 pNPIKARYVRF 686 *********96 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 1e-06 0.0051 2 28 .. 1018 1044 .. 1017 1047 .. 0.93 2 ? 2.7 0.0 0.039 2e+02 2 30 .] 1114 1142 .. 1113 1142 .. 0.85 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1e-06 EF-hand_6 2 lreaFklfDkdgdGyisleElraalrs 28 +r++F+ fD ++dGy+ eEl al+s FUN_001552-T1 1018 FRRVFNNFDENQDGYLFPEELLGALES 1044 79*********************9986 PP == domain 2 score: 2.7 bits; conditional E-value: 0.039 EF-hand_6 2 lreaFklfDkdgdGyisleElraalrslG 30 +++F+ + + + +isleEl+ l++ G FUN_001552-T1 1114 AKRLFSCYVDEAKKTISLEELILGLTAGG 1142 57899999888899********9998765 PP >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 7.6e-07 0.0039 3 47 .. 1017 1060 .. 1015 1069 .. 0.82 2 ? -0.9 0.1 0.62 3.2e+03 31 62 .. 1100 1134 .. 1087 1139 .. 0.61 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 7.6e-07 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfk 47 + +++F+ +D ++dGyl eel +l++ +++ lsd ++ ++ + FUN_001552-T1 1017 HFRRVFNNFDENQDGYLFPEELLGALES-VNSNLLSDSHISYIYR 1060 6799*****************7779998.8888888887766654 PP == domain 2 score: -0.9 bits; conditional E-value: 0.62 EF-hand_7 31 l.....eegeplsdeeveelfkef.DldkdGrisfeEF 62 l e++ +l++ + lf + D k +is+eE+ FUN_001552-T1 1100 LrldfkELDLKLQK--AKRLFSCYvDEAK-KTISLEEL 1134 24443344444444..6688888646666.69999997 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 3.1e-05 0.16 2 27 .. 1018 1043 .. 1017 1045 .. 0.88 2 ? -2.3 0.0 1.2 6.1e+03 16 27 .. 1128 1139 .. 1127 1140 .. 0.83 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.1e-05 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellk 27 ++++F+ fD ++dG++ eE++ +l FUN_001552-T1 1018 FRRVFNNFDENQDGYLFPEELLGALE 1043 899*************9999988876 PP == domain 2 score: -2.3 bits; conditional E-value: 1.2 EF-hand_1 16 kIdfeEfkellk 27 +I++eE++ l+ FUN_001552-T1 1128 TISLEELILGLT 1139 79*****98775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1196 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2095 (0.0820121); expected 510.9 (0.02) Passed bias filter: 592 (0.0231748); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.51u 0.42s 00:00:00.93 Elapsed: 00:00:00.43 # Mc/sec: 11345.63 // Query: FUN_001553-T1 [L=402] Description: FUN_001553 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-19 70.5 1.2 8.8e-19 68.4 1.2 2.0 1 PID Phosphotyrosine interaction domain (PTB/PID) 9.2e-09 35.5 0.0 1.5e-08 34.8 0.0 1.4 1 SH3_9 Variant SH3 domain 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.4 1 SH3_1 SH3 domain 0.00088 19.7 0.1 0.0034 17.8 0.1 1.9 1 PID_2 Phosphotyrosine interaction domain (PTB/PID) ------ inclusion threshold ------ 0.031 14.4 0.0 0.051 13.7 0.0 1.4 1 SH3_2 Variant SH3 domain 0.055 14.0 0.0 0.39 11.3 0.0 2.0 2 PTB Phosphotyrosine-binding domain Domain annotation for each model (and alignments): >> PID Phosphotyrosine interaction domain (PTB/PID) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.4 1.2 2.1e-22 8.8e-19 1 139 [. 239 391 .. 239 392 .. 0.76 Alignments for each domain: == domain 1 score: 68.4 bits; conditional E-value: 2.1e-22 PID 1 FavrylGsvevleerapdkstrsqvareaisrvkaaklkkikkkegetqegtevdLeistdklkllnadt.......................... 70 F r+lGsvev + + +++ + a++ + ++ ++++ t+++ ++L + ++++++++ FUN_001553-T1 239 FSLRFLGSVEVSSFK--GNE----IICSAMKEIVKQ-----HQMS-STAKPPACILDVTERGIRITEHPLgkgkgssgskksskhklgklferdsk 322 889********9992..333....333355555444.....2222.44555556666666666666655555666666666666666666666667 PP PID 71 .kelimdhplksIsfiadgdkdlkrrfayiardkatnklaChvfeseklakaiaqsigqaFelaykeflr 139 k + ++lk++ f+++ ++++ r+fa+i+++++++++aChvf+se +++a+a+++g aF+++y+ fl+ FUN_001553-T1 323 eKPNCHYFALKNVTFCGC-HPHNARFFAFITKHPEDHRFACHVFMSEFSTEAVATAVGVAFKKFYSDFLD 391 78899*************.************************************************986 PP >> SH3_9 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.8 0.0 3.6e-12 1.5e-08 1 48 [. 169 218 .. 169 219 .. 0.97 Alignments for each domain: == domain 1 score: 34.8 bits; conditional E-value: 3.6e-12 SH3_9 1 AlypyqpkeddeLslqeGdvitvieesedgWlegen..tGrtGlvPanyv 48 Aly ++++ dde l++Gd ++v +++ed W+eg n tG G +P+ yv FUN_001553-T1 169 ALYKFVARHDDETGLDPGDAVYVGKKCEDLWFEGVNlrTGKAGIFPSRYV 218 9**********************************889***********9 PP >> SH3_1 SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.2 0.0 4.8e-12 2e-08 1 48 [] 168 215 .. 168 215 .. 0.99 Alignments for each domain: == domain 1 score: 34.2 bits; conditional E-value: 4.8e-12 SH3_1 1 vAlYDYeaeesdELsfkkGdviivleksedgWwkgrlkdggkeGliPs 48 +AlY ++a+++dE + +Gd ++v +k ed W++g + ++gk G++Ps FUN_001553-T1 168 IALYKFVARHDDETGLDPGDAVYVGKKCEDLWFEGVNLRTGKAGIFPS 215 7**********************************************8 PP >> PID_2 Phosphotyrosine interaction domain (PTB/PID) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 8.1e-07 0.0034 2 103 .. 239 368 .. 238 392 .. 0.82 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 8.1e-07 PID_2 2 ykvvylGnvltilakGegCldkalskiWkkyeesk..advkmklkvtasGlkaetke............................rglteyl.shr 66 + + +lG v kG++ + a+++i k+ + s+ + l+vt++G++++++ ++ +y+ ++ FUN_001553-T1 239 FSLRFLGSVEVSSFKGNEIICSAMKEIVKQHQMSStaKPPACILDVTERGIRITEHPlgkgkgssgskksskhklgklferdskeKPNCHYFaLKN 334 66789999999999***********99999887742245567899*******9998899999********************99988888872588 PP PID_2 67 itycsapaeyPrvfaWvyrhegrklkvelrChavlvs 103 +t+c ++ r fa++ +h + + Ch + + FUN_001553-T1 335 VTFCGCHPHNARFFAFITKHPEDH---RFACHVFMSE 368 ********************8655...5678876654 PP >> SH3_2 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 1.2e-05 0.051 3 53 .. 168 219 .. 166 221 .. 0.88 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.2e-05 SH3_2 3 rvifdyvgtdkngLslkkGdvvkVlggkdddgwweget..gGrkGlvPstave 53 +++ ++v++ + l Gd v+V g+k +d w eg + G+ G++Ps +v+ FUN_001553-T1 168 IALYKFVARHDDETGLDPGDAVYV-GKKCEDLWFEGVNlrTGKAGIFPSRYVS 219 677788888899999999******.79999999***9999*********9996 PP >> PTB Phosphotyrosine-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.29 1.2e+03 1 54 [. 238 292 .. 238 295 .. 0.69 2 ? 11.3 0.0 9.1e-05 0.39 55 123 .. 320 384 .. 313 388 .. 0.88 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.29 PTB 1 qyrVehLttfeldskegvqavedairklqllda.kgrvwtqevllqVsdqgvtLl 54 q + +L ++e+ s +g++ + a+++ ++ + + +l V ++g++++ FUN_001553-T1 238 QFSLRFLGSVEVSSFKGNEIICSAMKEIVKQHQmSSTAKPPACILDVTERGIRIT 292 5677899999999999999998877654433330344456677888888888876 PP == domain 2 score: 11.3 bits; conditional E-value: 9.1e-05 PTB 55 DneskeelesypldsishcqavlnarrynsilalvakesesskddvhlFqcdelkaeliaediesalsk 123 D + k ++l+++++c +++ r+ +a++ k++e + h+F +e + e +a+++ a +k FUN_001553-T1 320 DSKEKPNCHYFALKNVTFCGCHPHNARF---FAFITKHPEDHRFACHVFM-SEFSTEAVATAVGVAFKK 384 55666677889**************998...9******************.*********999877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1094 (0.0428264); expected 510.9 (0.02) Passed bias filter: 681 (0.0266588); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 4022.54 // Query: FUN_001554-T1 [L=1317] Description: FUN_001554 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-43 149.5 13.9 1.7e-43 149.5 13.9 5.8 7 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.037 14.9 1.1 0.037 14.9 1.1 4.5 4 EhaL Energy-converting hydrogenase subunit EhaL Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.4 0.14 1.8e+03 93 124 .. 84 115 .. 67 120 .. 0.76 2 ? -2.4 0.1 0.3 3.8e+03 49 68 .. 179 198 .. 165 201 .. 0.76 3 ? -2.7 0.7 0.35 4.4e+03 18 57 .. 222 259 .. 212 278 .. 0.62 4 ? 0.8 4.9 0.03 3.8e+02 103 175 .. 308 379 .. 303 386 .. 0.77 5 ? -5.5 5.4 2 2.6e+04 168 227 .. 481 535 .. 450 642 .. 0.63 6 ? 0.2 0.1 0.047 6e+02 148 171 .. 873 897 .. 858 938 .. 0.71 7 ! 149.5 13.9 1.3e-47 1.7e-43 2 260 .] 1012 1271 .. 1011 1271 .. 0.91 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.14 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfs 124 ++++r+ +a+vl ++++ l + +l+p+l+ FUN_001554-T1 84 SRSRRSSLVAYVLSVLIFQLTSIYCLVPFLWK 115 34577788888888889988888888888855 PP == domain 2 score: -2.4 bits; conditional E-value: 0.3 xxxxxxxxxxxxxxxxxxxx RF 7tm_1 49 gdwvfgevlCklvtaldvvn 68 +w++ ++C ++++l++ FUN_001554-T1 179 FSWPVAPFFCIIFGFLFLQV 198 6899********99999765 PP == domain 3 score: -2.7 bits; conditional E-value: 0.35 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 18 ptnifllnLavaDllvlllvlpfalvyallegdwvfgevl 57 p + l++L + ll+ l+++p ++ + + w+f +++ FUN_001554-T1 222 PERFILTSLEKTLLLFNLVTVPGSMFIVI--NFWDFFHFM 259 55666778888888888889998886666..788887776 PP == domain 4 score: 0.8 bits; conditional E-value: 0.03 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 103 lvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvr 175 l+++++vW +++ ++p+++ ++ + +t+ ++ +++ + +++l++v+ fllp+++ +vc + FUN_001554-T1 308 LLCMILVWSGSVAPHVLPVIIGNVVCGVF-IWVTSGIDRWKVHQNASYLGLVILSLVGLFLLPCCLSVVCVFV 379 56788999999999999999888776653.55555555555566669999999999999999********875 PP == domain 5 score: -5.5 bits; conditional E-value: 2 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 168 vilvcyvrilrtlrksakkekskkkksarkerkalktllvvvvvfvlcwlPyfillllds 227 +++++ ++++++l +++ + +++++ + ++ ++ vv++ ++ lP+ ++++ ++ FUN_001554-T1 481 LLVFLFTFVVCKLIEAPGNLSRNEALK-----LCIASGVATVVTYDVLVLPLWFMMTHAI 535 444555555555555555555544433.....4555555555555555555555443333 PP == domain 6 score: 0.2 bits; conditional E-value: 0.047 x.xxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 148 t.wevsytlllsvlgfllpllvilv 171 + w+ +y+l +++l lp++vil+ FUN_001554-T1 873 WpWTLVYVLEMIILLCSLPTFVILM 897 2477777777777777777777765 PP == domain 7 score: 149.5 bits; conditional E-value: 1.3e-47 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykr 95 Nl ++ +ilr+k+ r+++++f++nLa++Dll++ l +p+ +v l+ ++w++g+++Ck+v+ ++++++ +s+ +lt+++i+RY aIv p+k FUN_001554-T1 1012 NLALCSAILRTKHPRKASEYFIFNLALTDLLTCSLGIPLDIVVILM-EHWPLGAFMCKVVYPFQTLLTAVSVATLTCMAIERYRAIVTPFKP-- 1102 99*******************************************6.*********************************************.. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 96 irtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 + + + +++ i++vW+l+++l+ p + + + + +C+ ++ ++ ++++tl++++l++ +pl+vi +y++i +l+++ + + FUN_001554-T1 1103 MFSVKIVKIAIIAVWCLSAILVSPYVAILKY-------RDLSCHEAWQG--DKLPKIFTLCVFLLFYAVPLSVIGPTYALIGVKLHSEGRILLN 1187 679**********************998875.......4669*****88..78***********************************999977 PP .................xxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .................kkkksarker.....kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + r +++t l ++f++c lPy+ + l++ + + ++ + + al++++ l y+ns+++P+i+ FUN_001554-T1 1188 fsrrqgqgnqqfralvrQ--------RtksniVIVRTFLFGAIAFAVCLLPYHAMWLWHDF-GQATRWTHFSDALIFANALVYFNSLVDPFIF 1271 666666666555443322........1444559999************************9.7788888888999****************95 PP >> EhaL Energy-converting hydrogenase subunit EhaL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.2 0.47 6e+03 39 70 .. 238 269 .. 222 272 .. 0.74 2 ? -1.7 0.1 0.45 5.8e+03 39 74 .. 392 429 .. 383 448 .. 0.75 3 ? -1.0 0.1 0.27 3.5e+03 34 69 .. 439 473 .. 410 481 .. 0.56 4 ? 14.9 1.1 2.9e-06 0.037 6 69 .. 543 603 .. 539 610 .. 0.76 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.47 EhaL 39 LvlavlGwlllnasflvlvplviligvlllaf 70 +++v G++ + ++f + + +i +ll ++ FUN_001554-T1 238 NLVTVPGSMFIVINFWDFFHFMTWIRLLLCGI 269 24678899999999999999999999999875 PP == domain 2 score: -1.7 bits; conditional E-value: 0.45 EhaL 39 LvlavlGwlllnasfl..vlvplviligvlllafvlgm 74 Lv+ +G +l + ++ +l p+ ++g +llaf l FUN_001554-T1 392 LVIHSVGFVLCEHVLVgeKLYPVYFSVGTMLLAFYLCE 429 66667777776665553346789999999999998755 PP == domain 3 score: -1.0 bits; conditional E-value: 0.27 EhaL 34 idklaLvlavlGwll.lnasflvlvplviligvllla 69 ++++L +av G+ + l s p + +++vll + FUN_001554-T1 439 SQSVSLCIAVHGSKIpLCLST--IFPYQPTAAVLLPS 473 467889999999988544443..33433345555444 PP == domain 4 score: 14.9 bits; conditional E-value: 2.9e-06 EhaL 6 avivfivGsllGLeysyrkykepyvekkidklaLvlavlGwlllnasflvlvplviligvllla 69 a++vfi G+ l L++sy++++++ + k+i+ l+L +vl ++ + f + + ++v+l++ FUN_001554-T1 543 AAVVFIWGA-LCLKLSYQHFSHIMTAKRINVLVLCSSVLVEII-QPDF-NIYRVLQAMTVYLVS 603 678999997.68**************************99988.3333.333334555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1181 (0.0462321); expected 510.9 (0.02) Passed bias filter: 448 (0.0175377); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.46u 0.38s 00:00:00.84 Elapsed: 00:00:00.43 # Mc/sec: 12491.66 // Query: FUN_001555-T1 [L=327] Description: FUN_001555 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-35 121.4 16.1 2.4e-32 112.9 16.1 2.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.3e-07 32.0 16.2 8.5e-07 29.3 1.3 2.1 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 9.5e-07 29.3 6.6 9.5e-07 29.3 6.6 2.1 2 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.31 11.4 0.2 0.31 11.4 0.2 3.3 3 Cortexin Cortexin of kidney Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 112.9 16.1 3.7e-36 2.4e-32 1 260 [] 37 281 .. 37 281 .. 0.82 Alignments for each domain: == domain 1 score: 112.9 bits; conditional E-value: 3.7e-36 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevl.CklvtaldvvnltasillltaisiDRYlaIvkplky 93 gNllV+l+il nk l++p n+f+ nLa++Dl v+++v p++++y+ ++ ++ + ++++ +++++tas+l+l+a+++DR++aI+ pl+y FUN_001555-T1 37 GNLLVLLAILIdpNKDLKSPFNYFVANLALCDLFVGFVVDPMSAAYHYS-EGSARKYPMkLVYLHIPYFISSTASVLSLAALTVDRFWAITSPLSY 131 8*********978899********************9999999988885.44444444414566788999************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 + + +++ra + l++W++++++ ++ l g t+ + f + +v+++++l++l +l ++ ++ + v+ + l +s+k ++ FUN_001555-T1 132 RIKLNPKRAGFAALGIWAFSICFPFIYLST-GYLTY---------AFVFAH-----TVIIATFLVMLLTYLKIFRVFKLKVKEWDSLNQSSKDSQA 212 *****************9998876666552.23322.........344444.....5677777777777777777777777777777777776666 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 k+++++ e+k++kt l+v+++f+ c+lP i + ++ l ++++s+ ++++a ++ ll+++ns +NP++Y FUN_001555-T1 213 -KRQAMKWEQKVTKTFLIVLAFFLACYLPSCICIYITNL-CSSCSCITIHWARDVHFLLILANSGVNPFVY 281 .555667888************************99999.77788889999*******************9 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 1.3 1.3e-10 8.5e-07 4 129 .. 31 158 .. 28 167 .. 0.84 2 ! 8.1 8.1 0.00041 2.6 158 252 .. 164 260 .. 159 263 .. 0.81 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 1.3e-10 7TM_GPCR_Srx 4 sliGlvlNllvliailk..lkslknsFgilclskaisnaiilliflfyvvPmtllqsellkellnshliglialglYeisplsqllialNRfcavf 97 +l+ + Nllvl+ail +k lk++F++ ++ a++++ + +++ + + +++ + k+ ++ ++++ ++ +s ls ++++Rf+a+ FUN_001555-T1 31 TLVTVTGNLLVLLAILIdpNKDLKSPFNYFVANLALCDLFVGFVVDPMSAAYHYSEGSARKYPMKLVYLHIPYFISSTASVLSLAALTVDRFWAIT 126 55566678888777665115679****************9999988888888888888889999998999999999999***************** PP 7TM_GPCR_Srx 98 fplkyekifsiknTkiiiviiwivslifitvl 129 pl y + k + ++ + iw++s++f +++ FUN_001555-T1 127 SPLSYRIKLNPKRAGFAALGIWAFSICFPFIY 158 **************************975543 PP == domain 2 score: 8.1 bits; conditional E-value: 0.00041 7TM_GPCR_Srx 158 swyldfllililviitlvlnlltaikli.lskkksks...tsseeskrrrkreinffkQsvlQdllflidlvnyfliaplvenkwlqfilttlswv 249 +y+ f++ +++i+t+++ llt++k++ ++k k k+ ++++++++ kr+ + Q+v +l+++ + +++++ + +++ ++++ s FUN_001555-T1 164 LTYA-FVFAHTVIIATFLVMLLTYLKIFrVFKLKVKEwdsLNQSSKDSQAKRQAMKWEQKVTKTFLIVLAFFLACYLPSCI-CIYITNLCSSCSCI 257 5677.99999*****************9988877764322566677888899999999*****************999977.56777777777777 PP 7TM_GPCR_Srx 250 fvh 252 ++h FUN_001555-T1 258 TIH 260 776 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 6.6 1.5e-10 9.5e-07 3 150 .. 29 176 .. 27 198 .. 0.74 2 ? 0.8 0.1 0.077 4.9e+02 219 277 .. 235 296 .. 215 298 .. 0.60 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 1.5e-10 7tm_4 3 lvyliillGnltilf..vikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffih.kfsllesav...llamavdr 92 ++ l++++Gnl +l +i ++ l+ P +f+a lal dl + P + e s ++l+++h ++++ +a+ l+a +vdr FUN_001555-T1 29 VMTLVTVTGNLLVLLaiLIDPNKDLKSPFNYFVANLALCDLFVGFVVDPMSAAY---HYSEGSARKYPMKLVYLHiPYFISSTASvlsLAALTVDR 121 6889*******9987224567799********************9999977654...556667777778888888346666666512245778*** PP 7tm_4 93 fvaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsycl 150 f ai spl y l k+ + +l+++ s+ +p+i+l + ++ v +h+ ++ FUN_001555-T1 122 FWAITSPLSYRIKLNPKRAGFAALGIWAFSIC--FPFIYLSTGYLTYA-FVFAHTVII 176 ***********99999999*******988877..88888754333222.244444333 PP == domain 2 score: 0.8 bits; conditional E-value: 0.077 7tm_4 219 lafyvPmiglsvvhrfgkkvsrl.lqvl..lanlyllfPPvlnPivysvktkeirdavvkil 277 la y P + + s + ++ + +l +l +nP vy+ + + r a v++l FUN_001555-T1 235 LACYLPSCICIYITNLCSSCSCItIHWArdVHFLLILANSGVNPFVYAWRLEKFRTAFVQLL 296 45555554444444444444432133331133455556677899999888888888877766 PP >> Cortexin Cortexin of kidney # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.1 0.1 6.5e+02 28 51 .. 28 50 .. 10 56 .. 0.64 2 ? 1.8 1.4 0.048 3e+02 25 50 .. 169 199 .. 163 213 .. 0.58 3 ? 11.4 0.2 4.8e-05 0.31 11 48 .. 210 247 .. 201 262 .. 0.84 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.1 Cortexin 28 fvilLlifLglLivrCfriLLDPY 51 v+ L+ + g L+v + iL+DP FUN_001555-T1 28 IVMTLVTVTGNLLV-LLAILIDPN 50 45555555555555.356677765 PP == domain 2 score: 1.8 bits; conditional E-value: 0.048 Cortexin 25 vfafvilLlifLglL.....ivrCfriLLDP 50 vfa +++ fL++L i r f++ + FUN_001555-T1 169 VFAHTVIIATFLVMLltylkIFRVFKLKVKE 199 5666666666777662222244666655555 PP == domain 3 score: 11.4 bits; conditional E-value: 4.8e-05 Cortexin 11 nevsavslsleqktvfafvilLlifLglLivrCfriLL 48 ++ + +++ eqk + +f i+L fL+ + C+ i + FUN_001555-T1 210 SQAKRQAMKWEQKVTKTFLIVLAFFLACYLPSCICIYI 247 5567789*********************9999998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (327 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1611 (0.0630652); expected 510.9 (0.02) Passed bias filter: 634 (0.0248189); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 3283.29 // Query: FUN_001556-T1 [L=339] Description: FUN_001556 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-33 116.5 16.8 6.3e-31 108.3 16.8 2.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.2e-10 41.7 14.6 5.3e-10 39.6 14.6 1.8 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 5.1e-08 33.3 18.6 1.7e-07 31.6 3.4 2.1 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 5.3e-07 29.9 3.0 5.3e-07 29.9 3.0 2.8 2 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc ------ inclusion threshold ------ 0.12 12.7 0.1 0.12 12.7 0.1 3.0 3 Cortexin Cortexin of kidney Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 108.3 16.8 1.2e-34 6.3e-31 1 260 [] 37 281 .. 37 281 .. 0.82 Alignments for each domain: == domain 1 score: 108.3 bits; conditional E-value: 1.2e-34 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkyk 94 gNllV+l+i+ nk l++p n+f+ nLa++Dl v++lv p+++vy+ eg + + ++++ +++++tas+l+l+a+++DR++aI p++y+ FUN_001556-T1 37 GNLLVVLAIFIdpNKDLKSPFNYFVANLAICDLFVGFLVDPLSIVYHYSEGAAKRFPANRVFLYIPYFISCTASVLSLAALTVDRFWAISFPISYR 132 8******999978899****************************99995443333333334566678899************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 95 rirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeksk 190 ++ +++ra + +++W+++l + ++ ll g t+ + f + +v+++++l++l +l ++ ++ + ++ + t+ ++++++ FUN_001556-T1 133 NKLNPKRAGFAAAGIWTFSLGFPFVILLT-GYLTY---------AFVFAH-----TVIIATFLVMLLTYLKIFRVFKLKIKQWETMDFASSEKEA- 212 ********************999999884.34444.........344444.....5666666666666666666666666666666666665555. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 191 kkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 k+++++ e+k++kt l+++++f+ c+lP i + ++ l ++++s+ ++++a ++ ll+++ns +NP++Y FUN_001556-T1 213 KRQAMKWEQKVTKTFLIMLAFFLACYLPSCICIYITNL-CSSCSCIFIHWARDVHFLLILANSGVNPFVY 281 555667888***********************999999.888899999*********************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.6 14.6 1e-13 5.3e-10 2 256 .. 32 295 .. 31 296 .. 0.74 Alignments for each domain: == domain 1 score: 39.6 bits; conditional E-value: 1e-13 7TM_GPCR_Srsx 2 vvGliGNvllilltfk..kkkLrskssiLicvqcladllc..lvgelvfvvlll..tgtqlkreeCFlliivyvfgltaqsvllLvigiDlliavk 91 +v ++GN+l++l++f +k L+s++++ + ++++dl++ lv+ l v++ + +++ + Fl+ i+y ++ ta+ + l ++++D++ a++ FUN_001556-T1 32 LVTITGNLLVVLAIFIdpNKDLKSPFNYFVANLAICDLFVgfLVDPLSIVYHYSegAAKRFPANRVFLY-IPYFISCTASVLSLAALTVDRFWAIS 126 6889***********844689*****************9732334343333333003333444444443.46666666666666689********* PP 7TM_GPCR_Srsx 92 fPirYrllskek...Ylli.llifpvlyssiilvlgflqrdde..tiivCapplalagkaseiftlssliinvivllvylvliiilkkkkekkkss 181 fPi Yr+ + k + ++ +f + + +il+ g+l+ ++ a l++ + +if ++ l i+ ++ ++ + + k + ++ FUN_001556-T1 127 FPISYRNKLNPKragFAAAgIWTFSLGFPFVILLTGYLTYAFVfaHTVIIATFLVMLLTYLKIFRVFKLKIKQWETMDFASSEKEA---KRQAMKW 219 ******98888778865542678999999999999999877663334444555666677778888888888887777777765553...3335688 PP 7TM_GPCR_Srsx 182 skkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfs.qnffVtywrsseYrkafrel 256 +kv k +++ +f+ + + s i+ ++ ++ + + + +l++l+ s n fV+ wr +++rkaf +l FUN_001556-T1 220 EQKVTKTFLIMLAFFLACYLPSCICIYITNLCSSCSCIFIHWARDVHFLLILANSgVNPFVYAWRFDNFRKAFVKL 295 899*******************99999998888888777777777777666655538****************987 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.6 3.4 3.3e-11 1.7e-07 5 130 .. 32 159 .. 29 170 .. 0.71 2 ! 6.3 9.4 0.0018 9 159 253 .. 165 261 .. 159 264 .. 0.86 Alignments for each domain: == domain 1 score: 31.6 bits; conditional E-value: 3.3e-11 7TM_GPCR_Srx 5 liGlvlNllvliailk..lkslknsFgilclskaisnaiilliflfyvvPmtllqsell.kellnshliglialgl.YeisplsqllialNRfcav 96 l+ + Nllv++ai+ +k lk++F++ ++ ai+++ + + l+ + +++ +se k++ +++ +i +++ +s ls ++++Rf+a+ FUN_001556-T1 32 LVTITGNLLVVLAIFIdpNKDLKSPFNYFVANLAICDLFVGF--LVDPLSIVYHYSEGAaKRFPANRVFLYIPYFIsCTASVLSLAALTVDRFWAI 125 55566788888777651156789**************87654..4444444444443334444333455554444414567788889********* PP 7TM_GPCR_Srx 97 ffplkyekifsiknTkiiiviiwivslifitvly 130 fp+ y + + k + ++ + iw++sl f +v++ FUN_001556-T1 126 SFPISYRNKLNPKRAGFAAAGIWTFSLGFPFVIL 159 ***************************9876655 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0018 7TM_GPCR_Srx 159 wyldfllililviitlvlnlltaikli.lskkksks...tsseeskrrrkreinffkQsvlQdllflidlvnyfliaplvenkwlqfilttlswvf 250 +y+ f++ +++i+t+++ llt++k++ ++k k k+ ++ ++s+++ kr+ + Q+v +l+++ + +++++ + +++ ++++ s f FUN_001556-T1 165 TYA-FVFAHTVIIATFLVMLLTYLKIFrVFKLKIKQwetMDFASSEKEAKRQAMKWEQKVTKTFLIMLAFFLACYLPSCI-CIYITNLCSSCSCIF 258 677.99999*****************998887777522245567899999***************************988.789999999999999 PP 7TM_GPCR_Srx 251 vha 253 +h FUN_001556-T1 259 IHW 261 995 PP >> 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 3.0 1e-10 5.3e-07 3 119 .. 18 134 .. 17 160 .. 0.81 2 ? -8.2 11.5 5 2.6e+04 37 66 .. 221 250 .. 163 279 .. 0.49 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 1e-10 7TM_GPCR_Srbc 3 liavvvtligilfsiitivlniylllkiflkkkikkkkdlvLfyfrfal.Dvvyslsvsiyllyvlllsiskeel.vknlifylglpssnigaiRs 96 +ia+++++++ ++s++ti n+ ++l+if++ + k+ + f+ +a+ D++++++v +++ ++ + + + +++y+ +++s ++++ s FUN_001556-T1 18 YIAFISSSLSGVMSLVTITGNLLVVLAIFIDPNKDLKSPFNYFVANLAIcDLFVGFLVDPLSIVYHYSEGAAKRFpANRVFLYIPYFISCTASVLS 113 6899***************************9999**********99755********99999999999999998555566666666666555555 PP 7TM_GPCR_Srbc 97 ilallIsleRviAvyfPifyhny 119 + +++++R++A+ fPi+y+n+ FUN_001556-T1 114 L--AALTVDRFWAISFPISYRNK 134 4..45689*************96 PP == domain 2 score: -8.2 bits; conditional E-value: 5 7TM_GPCR_Srbc 37 kkkkdlvLfyfrfalDvvyslsvsiyllyv 66 +k ++ L+++ f+l + +++iy++ + FUN_001556-T1 221 QKVTKTFLIMLAFFLACYLPSCICIYITNL 250 333344556666666666666666655544 PP >> Cortexin Cortexin of kidney # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 2.1 1.1e+04 32 48 .. 39 47 .. 26 53 .. 0.57 2 ? -0.1 2.9 0.24 1.2e+03 25 41 .. 169 185 .. 161 207 .. 0.62 3 ? 12.7 0.1 2.4e-05 0.12 8 47 .. 207 246 .. 200 256 .. 0.86 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 2.1 Cortexin 32 LlifLglLivrCfriLL 48 Ll++L+ i + FUN_001556-T1 39 LLVVLA--------IFI 47 344444........444 PP == domain 2 score: -0.1 bits; conditional E-value: 0.24 Cortexin 25 vfafvilLlifLglLiv 41 vfa +++ fL++L+ FUN_001556-T1 169 VFAHTVIIATFLVMLLT 185 56666666677776642 PP == domain 3 score: 12.7 bits; conditional E-value: 2.4e-05 Cortexin 8 psgnevsavslsleqktvfafvilLlifLglLivrCfriL 47 s e + +++ eqk + +f i+L fL+ + C+ i FUN_001556-T1 207 SSEKEAKRQAMKWEQKVTKTFLIMLAFFLACYLPSCICIY 246 5677788899********************9999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (339 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1633 (0.0639264); expected 510.9 (0.02) Passed bias filter: 655 (0.025641); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.37s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 3280.21 // Query: FUN_001557-T1 [L=353] Description: FUN_001557 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-34 119.0 16.3 8.4e-24 84.9 2.0 2.1 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.2e-11 45.0 11.2 7.4e-10 39.1 11.2 2.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 3.6e-09 37.1 3.7 3.6e-09 37.1 3.7 2.3 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 1.5e-05 25.1 6.6 1.5e-05 25.1 6.6 2.8 3 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.9 2.0 1.3e-27 8.4e-24 1 122 [. 37 160 .. 37 165 .. 0.89 2 ! 39.4 7.6 1e-13 6.6e-10 151 260 .] 164 282 .. 159 282 .. 0.85 Alignments for each domain: == domain 1 score: 84.9 bits; conditional E-value: 1.3e-27 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkyk 94 gNllV+l+i+ nk l++p n+f+ nLa++Dllv++lv p++++y+ eg + + ++++ +++++tas+l+l+a+++DR++aI p++y+ FUN_001557-T1 37 GNLLVVLAIFIdpNKDLKSPFNYFVANLAICDLLVGFLVDPMSVAYHYSEGAAKRFPASRVYLHIPYFISCTASVLSLAALTVDRFWAISFPISYR 132 8******999978899***************************99988554443334444579999****************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 95 rirtkrralvlilvvWvlalllslppll 122 ++ +++ra + +++W++++++s++ + FUN_001557-T1 133 NKLNPKRAGFAAAGIWAFSICFSFVYFS 160 ***********************98765 PP == domain 2 score: 39.4 bits; conditional E-value: 1e-13 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 151 vsytlllsvlgfllpllvilvcyvrilrtlrksakkeks..........kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkecesek 236 +y++++ + ++ +lv+l +y++i+r+ + + k+ +s k+++++ e+k++k l+++++f+ c+lP i + ++ l + ++s+ FUN_001557-T1 164 LTYAFVFAHTVIIVTFLVMLLTYFKIVRHFKLKVKEWDSlnlagakdsqAKRQAMKWEEKVAKAFLIMLAFFLACYLPSCICIYITNL-CISCSCI 258 455666666667779**********************9999998887764555556667************************99999.6667778 PP xxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 237 lvetallitlllayvnsclNPiiY 260 +++a ++ l++++ns +NP++Y FUN_001557-T1 259 SIHWARDVHFLFILANSGVNPFVY 282 889999*****************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 11.2 1.2e-13 7.4e-10 2 256 .. 32 296 .. 31 297 .. 0.67 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 1.2e-13 7TM_GPCR_Srsx 2 vvGliGNvllilltfk..kkkLrskssiLicvqcladllc..lvgelvfvvllltgtqlkreeCFlliivyvfgltaqsvllL.vigiDlliavkf 92 +v ++GN+l++l++f +k L+s++++ + ++++dll+ lv+ + +++ +g + +++ ++ f +++svl L ++++D++ a++f FUN_001557-T1 32 LVTITGNLLVVLAIFIdpNKDLKSPFNYFVANLAICDLLVgfLVDPMSVAYHYSEGAAKRFPASRVYLHIPYFISCTASVLSLaALTVDRFWAISF 127 6889***********844689*****************973244455555555544443333444444455566666666666279********** PP 7TM_GPCR_Srsx 93 PirYrllskek.........YllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkekkk 179 Pi Yr+ + k + + ++ v +s++ l + f+++ + +i++ ++l k + f+l + + l + k++ + FUN_001557-T1 128 PISYRNKLNPKragfaaagiWAFSICFSFVYFSTSYLTYAFVFAHTVIIVTFLVMLLTYFKIVRHFKLKVKEWDSLNL----AGAKDSQAKRQ-AM 218 *****9888876785555555555555555556666666666666665555555555444444444444443333222....11222222222.67 PP 7TM_GPCR_Srsx 180 ssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagi.lvllsfsqnffVtywrsseYrkafrel 256 + +kv k +++ +f+ + + s i+ ++ + + ++ + + ++l ++ n fV+ wr +++r+af +l FUN_001557-T1 219 KWEEKVAKAFLIMLAFFLACYLPSCICIYITNLCISCSCISIHWARDVHFlFILANSGVNPFVYAWRLDNFRRAFVKL 296 8889******************9999988887777766666666666655155666679****************987 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.1 3.7 5.6e-13 3.6e-09 5 131 .. 32 160 .. 29 168 .. 0.75 2 ? 1.7 7.1 0.036 2.3e+02 156 252 .. 162 261 .. 159 269 .. 0.69 Alignments for each domain: == domain 1 score: 37.1 bits; conditional E-value: 5.6e-13 7TM_GPCR_Srx 5 liGlvlNllvliailk..lkslknsFgilclskaisnaiilliflfyvvPmtllqsellkellnshliglial.glYeisplsqllialNRfcavf 97 l+ + Nllv++ai+ +k lk++F++ ++ ai+++++ +++ + v +++ k++ s++ +i + + +s ls ++++Rf+a+ FUN_001557-T1 32 LVTITGNLLVVLAIFIdpNKDLKSPFNYFVANLAICDLLVGFLVDPMSVAYHYSEGAA-KRFPASRVYLHIPYfISCTASVLSLAALTVDRFWAIS 126 5556678888877765115678***************988655554444444444444.666666655555550556788999999********** PP 7TM_GPCR_Srx 98 fplkyekifsiknTkiiiviiwivslifitvlyl 131 fp+ y + + k + ++ + iw++s++f++v++ FUN_001557-T1 127 FPISYRNKLNPKRAGFAAAGIWAFSICFSFVYFS 160 ***************************9998774 PP == domain 2 score: 1.7 bits; conditional E-value: 0.036 7TM_GPCR_Srx 156 tiswyldfllililviitlvlnlltaikli.lskkkskstssees....krrrkreinffkQsvlQdllflidlvnyfliaplvenkwlqfilttl 246 ++ +y+ f++ +++i+t+++ llt++k++ +k k k+ +s + +++ kr+ + +v ++l+++ + +++++ + +++ ++++ FUN_001557-T1 162 SYLTYA-FVFAHTVIIVTFLVMLLTYFKIVrHFKLKVKEWDSLNLagakDSQAKRQAMKWEEKVAKAFLIMLAFFLACYLPSCI-CIYITNLCISC 255 566787.9*********************9777777665444322333367777777777888888888888888888877755.34444444444 PP 7TM_GPCR_Srx 247 swvfvh 252 s ++h FUN_001557-T1 256 SCISIH 261 444444 PP >> 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 6.6 2.4e-09 1.5e-05 3 137 .. 18 156 .. 17 168 .. 0.80 2 ? -2.5 5.9 0.61 3.9e+03 54 92 .. 147 185 .. 139 198 .. 0.53 3 ? 0.9 0.8 0.056 3.6e+02 42 88 .. 227 274 .. 215 280 .. 0.70 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 2.4e-09 7TM_GPCR_Srbc 3 liavvvtligilfsiitivlniylllkiflkkkikkkkdlvLfyfrfal.DvvyslsvsiyllyvlllsiskeelvknlifylglpssnigaiRsi 97 +ia+++++++ ++s++ti n+ ++l+if++ + k+ + f+ +a+ D++++++v + + + ++ + + +yl +p ++ ++ ++ FUN_001557-T1 18 YIAFISSSLSGVMSLVTITGNLLVVLAIFIDPNKDLKSPFNYFVANLAIcDLLVGFLVDPMSVAYHYSEGAAKRF-PASRVYLHIPYFISCTASVL 112 6899*************************9999999999999999997559999999988888887777777666.44556777777777777777 PP 7TM_GPCR_Srbc 98 lallIsleRviAvyfPifyhny....rskipnllililiillgl 137 +++++R++A+ fPi+y+n+ r + i+ + i++ + FUN_001557-T1 113 SLAALTVDRFWAISFPISYRNKlnpkRAGFAAAGIWAFSICFSF 156 778889**************963333666777777777777665 PP == domain 2 score: -2.5 bits; conditional E-value: 0.61 7TM_GPCR_Srbc 54 vyslsvsiyllyvlllsiskeelvknlifylglpssnig 92 + +s+++ ++y+ +++++ +++ + +++++++++ + FUN_001557-T1 147 IWAFSICFSFVYFSTSYLTYAFVFAHTVIIVTFLVMLLT 185 556666666666666666666663333333333333222 PP == domain 3 score: 0.9 bits; conditional E-value: 0.056 7TM_GPCR_Srbc 42 lvLfyfrfalDvvyslsvsiyllyvlll.siskeelvknlifylglps 88 L+++ f+l + +++iy++ + ++ s+ + + + f+++l+ FUN_001557-T1 227 AFLIMLAFFLACYLPSCICIYITNLCIScSCISIHWARDVHFLFILAN 274 568888999999999999999886555314444444777777776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (353 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1268 (0.0496379); expected 510.9 (0.02) Passed bias filter: 437 (0.0171071); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.39 # Mc/sec: 3636.59 // Query: FUN_001558-T1 [L=401] Description: FUN_001558 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (401 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1054 (0.0412605); expected 510.9 (0.02) Passed bias filter: 563 (0.0220395); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4059.45 // Query: FUN_001559-T1 [L=732] Description: FUN_001559 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-17 64.5 0.1 4.8e-17 63.1 0.1 1.8 1 Filamin Filamin/ABP280 repeat 5.8e-13 49.2 0.4 1.2e-05 25.1 0.5 2.6 2 DUF5128 6-bladed beta-propeller 6.3e-11 42.7 22.3 1.4e-08 35.2 7.1 4.2 4 zf-B_box B-box zinc finger 1.3e-09 38.1 4.9 0.051 14.1 0.0 5.6 6 NHL NHL repeat 6.4e-09 36.2 3.7 6.4e-09 36.2 3.7 3.6 1 zf-RING_UBOX RING-type zinc-finger 1.4e-06 28.5 5.9 1.4e-06 28.5 5.9 3.9 3 zf-C3HC4 Zinc finger, C3HC4 type (RING fing 2.4e-06 28.0 7.7 2.4e-06 28.0 7.7 3.6 1 zf-C3HC4_4 zinc finger of C3HC4-type, RING 3.6e-06 27.2 7.8 3.6e-06 27.2 7.8 3.9 3 zf-C3HC4_2 Zinc finger, C3HC4 type (RING fing 9.1e-05 22.7 7.0 9.1e-05 22.7 7.0 3.7 3 zf-C3HC4_3 Zinc finger, C3HC4 type (RING fing 0.00026 21.5 21.3 0.00087 19.8 8.0 4.0 3 ANCHR-like_BBOX ANCHR-like B-box zinc-binding doma 0.00035 21.3 8.1 0.00035 21.3 8.1 3.9 2 zf-RING_2 Ring finger domain 0.001 19.4 11.0 0.0023 18.3 11.0 1.6 1 TRIM_CC TRIM protein coiled-coil region 0.0053 16.5 0.1 0.051 13.2 0.0 2.5 3 SdiA-regulated SdiA-regulated ------ inclusion threshold ------ 0.023 15.7 0.0 0.053 14.5 0.0 1.5 1 Invasin_D3 Invasin, domain 3 0.047 13.4 0.0 0.24 11.1 0.0 2.1 2 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 1.1 9.6 20.1 2.5 8.4 20.1 1.5 1 ARGLU Arginine and glutamate-rich 1 1.5 8.9 8.8 3.1 7.8 8.8 1.5 1 FIN1 Filaments in between nuclei protei 3 8.4 6.8 5.2 7.7 6.8 1.3 1 Mit_KHE1 Mitochondrial K+-H+ exchange-relat 4.4 7.9 41.9 0.038 14.5 9.6 4.3 4 zf-RING_5 zinc-RING finger domain 7 6.8 10.0 12 6.0 10.0 1.4 1 Med4 Vitamin-D-receptor interacting Med 7.1 6.3 10.0 10 5.7 10.0 1.2 1 TMEM120A-B TMEM120A/B 7.5 7.2 12.4 6.7 7.4 8.0 2.6 2 DUF5446 Family of unknown function (DUF544 7.7 7.1 10.5 16 6.1 10.5 1.4 1 DUF1664 Protein of unknown function (DUF16 9.2 6.9 20.8 2.8 8.5 7.9 2.8 2 zf-B_box_ZFPL1 ZFPL1-like, B-box zinc-binding dom Domain annotation for each model (and alignments): >> Filamin Filamin/ABP280 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.1 0.1 4.5e-20 4.8e-17 2 92 .. 365 459 .. 364 459 .. 0.91 Alignments for each domain: == domain 1 score: 63.1 bits; conditional E-value: 4.5e-20 Filamin 2 adaskvkvsGpglepgvvgkpaeFtvdtrdaggekvtg....fevevtgpkgkkvevevednkdgtytvsYtptepgkytvsVkfngqhipgsPf 92 +d+s++ + g ++ + +++F v tr+ +g ++ + +ev + +p++ ++ +++d+kdg+ytv+Ytp+ +g+++v++ +ngq+++gsP+ FUN_001559-T1 365 TDPSMCLAGCRGSKEIIEKNETTFVVVTRNSEGFPCYQqddqVEVGIFTPDNGELRPNIQDTKDGRYTVTYTPQCAGRHRVQIQVNGQPLAGSPW 459 89******666643336669****************99999999999***********************************************6 PP >> DUF5128 6-bladed beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.0 1.8e-07 0.00019 74 140 .. 472 537 .. 471 588 .. 0.82 2 ! 25.1 0.5 1.1e-08 1.2e-05 51 136 .. 623 706 .. 618 725 .. 0.85 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 1.8e-07 DUF5128 74 firkIgaqGnGPgEYlqlndfiidksnesIyildfmkkKiltYdLdgysfleeikldllvsdclqle 140 f + g+qGnGPgE+ q+ d ++ ++ I++ d ++kKi + dg +fl+e ++ ++ +++ ++ FUN_001559-T1 472 FSFVFGSQGNGPGEFNQPFDTAVSRKTGAIAVPDMQNKKIQLFCSDG-KFLREVRVVSEPFSVAFTD 537 777889*************************9999999998898877.*****99877775554444 PP == domain 2 score: 25.1 bits; conditional E-value: 1.1e-08 DUF5128 51 vddrifvlDsaknn.lfvFdkkGkfirkIgaqGnGPgEYlqlndfiidksnesIyildfmkkKiltYdLdgysfleeikldllvsdc 136 +++++fv ++ + vFdk+Gk+ + Ig++G+ g + + iidk+n ++++ d+ ++++ + Ldg fl+ + d++ + c FUN_001559-T1 623 HQEKYFVSYP-DSHcVKVFDKTGKYLFDIGSKGSRDGLFRWPRGLIIDKYN-QLIVSDANNQRLQFFTLDG-TFLHKLQGDFFSNGC 706 6788999333.355699*******************************999.6667***9999999***88.*****9999997666 PP >> zf-B_box B-box zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.9 4.6 4.9e+03 14 21 .. 32 39 .. 29 42 .. 0.77 2 ! 22.2 7.2 1.6e-07 0.00017 2 38 .. 100 142 .. 99 146 .. 0.89 3 ! 35.2 7.1 1.3e-11 1.4e-08 5 41 .. 163 201 .. 159 202 .. 0.89 4 ? -0.8 0.0 2.3 2.5e+03 11 20 .. 508 517 .. 506 518 .. 0.85 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 4.6 zf-B_box 14 lelyCedC 21 l+++C +C FUN_001559-T1 32 LHSFCLEC 39 56788888 PP == domain 2 score: 22.2 bits; conditional E-value: 1.6e-07 zf-B_box 2 kerkCpeHke.eplelyCedCqqllCeeCsvgeHr......gHk 38 + r+C+ ++e +p + yC Cq +lC++C +++Hr gH+ FUN_001559-T1 100 QARVCNSCEEnNPPICYCFVCQNFLCSSC-LESHRrlratrGHR 142 6789*****88******************.*****888887786 PP == domain 3 score: 35.2 bits; conditional E-value: 1.3e-11 zf-B_box 5 kCpe..HkeeplelyCedCqqllCeeCsvgeHrgHkvvp 41 +C + H+++ple+yC+dC+ l+C++Csv H++H+++ FUN_001559-T1 163 MCSQshHEDQPLEFYCKDCKLLICNKCSVVRHNRHSITD 201 688776888***************************986 PP == domain 4 score: -0.8 bits; conditional E-value: 2.3 zf-B_box 11 eeplelyCed 20 +++++l+C d FUN_001559-T1 508 NKKIQLFCSD 517 699*****86 PP >> NHL NHL repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 3.9 4.1e+03 21 27 .. 441 447 .. 439 447 .. 0.84 2 ? -0.5 0.0 2.1 2.2e+03 1 17 [. 486 503 .. 486 512 .. 0.86 3 ! 8.6 0.0 0.0026 2.7 3 19 .. 572 588 .. 570 593 .. 0.88 4 ? -0.8 0.0 2.5 2.6e+03 22 28 .] 634 640 .. 633 640 .. 0.90 5 ! 14.1 0.0 4.8e-05 0.051 1 26 [. 660 685 .. 660 687 .. 0.95 6 ! 11.5 0.2 0.00032 0.34 3 28 .] 706 731 .. 704 731 .. 0.91 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 3.9 NHL 21 enhrvqv 27 ++hrvq+ FUN_001559-T1 441 GRHRVQI 447 79***97 PP == domain 2 score: -0.5 bits; conditional E-value: 2.1 NHL 1 fnrPhGvavd.sdGdiyV 17 fn+P + av+ ++G i V FUN_001559-T1 486 FNQPFDTAVSrKTGAIAV 503 89999*****9*999988 PP == domain 3 score: 8.6 bits; conditional E-value: 0.0026 NHL 3 rPhGvavdsdGdiyVaD 19 +P+ ++v sdG+i+V+D FUN_001559-T1 572 QPEHLSVASDGRIIVCD 588 78999************ PP == domain 4 score: -0.8 bits; conditional E-value: 2.5 NHL 22 nhrvqvF 28 +h+v+vF FUN_001559-T1 634 SHCVKVF 640 7*****9 PP == domain 5 score: 14.1 bits; conditional E-value: 4.8e-05 NHL 1 fnrPhGvavdsdGdiyVaDsenhrvq 26 f++P+G+ +d+ ++++V+D +n+r+q FUN_001559-T1 660 FRWPRGLIIDKYNQLIVSDANNQRLQ 685 899**********************9 PP == domain 6 score: 11.5 bits; conditional E-value: 0.00032 NHL 3 rPhGvavdsdGdiyVaDsenhrvqvF 28 +P v++++d+ ++VaD+ h++ vF FUN_001559-T1 706 CPLYVTISNDDSLFVADFQKHCIIVF 731 667799*****************999 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.2 3.7 6e-12 6.4e-09 1 38 [. 16 57 .. 16 58 .. 0.89 Alignments for each domain: == domain 1 score: 36.2 bits; conditional E-value: 6e-12 zf-RING_UBOX 1 CpICleeftdPlv.lpCGHtfCreCl....welskkekgkikC 38 Cp Cle +++P + lpC H+fC eCl + +++ +++i+C FUN_001559-T1 16 CPLCLEILKNP-RtLPCLHSFCLECLdrqaKFAREQLQTSIRC 57 ***********.635***********99998888888888888 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 5.9 1.4e-09 1.4e-06 1 40 [] 16 60 .. 16 60 .. 0.85 2 ? -0.2 0.2 1.2 1.3e+03 1 12 [. 57 68 .. 57 71 .. 0.82 3 ? 0.6 8.7 0.68 7.2e+02 1 31 [. 104 134 .. 104 144 .. 0.87 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.4e-09 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCikslle......snnvkCplC 40 Cp+Cle lk+p +lpC+HsfC +C++ + +++ C C FUN_001559-T1 16 CPLCLEILKNPR-TLPCLHSFCLECLDRQAKfareqlQTSIRCSIC 60 ************.*************99888887666555557777 PP == domain 2 score: -0.2 bits; conditional E-value: 1.2 zf-C3HC4 1 CpiCleelkepv 12 C+iC + ++ p FUN_001559-T1 57 CSICRTSIEIPE 68 ****99988775 PP == domain 3 score: 0.6 bits; conditional E-value: 0.68 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCikslle 31 C+ C e+ + + + C+ +CssC++s+ + FUN_001559-T1 104 CNSCEENNPPICYCFVCQNFLCSSCLESHRR 134 999**999999999**************988 PP >> zf-C3HC4_4 zinc finger of C3HC4-type, RING # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.0 7.7 2.3e-09 2.4e-06 1 42 [] 16 60 .. 16 60 .. 0.82 Alignments for each domain: == domain 1 score: 28.0 bits; conditional E-value: 2.3e-09 zf-C3HC4_4 1 CpvCldyLekPvsieCGhsfClsCiss...lqkepdgesllCplC 42 Cp Cl+ L++P +++C hsfCl+C+ + + +e+ ++s C C FUN_001559-T1 16 CPLCLEILKNPRTLPCLHSFCLECLDRqakFAREQLQTSIRCSIC 60 *************************86222556666777888877 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 7.8 3.3e-09 3.6e-06 1 30 [. 15 43 .. 15 60 .. 0.87 2 ? -1.1 0.1 2.3 2.5e+03 1 12 [. 56 67 .. 56 70 .. 0.80 3 ? -2.4 1.7 5.8 6.1e+03 15 26 .. 178 189 .. 156 193 .. 0.77 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 3.3e-09 zf-C3HC4_2 1 eCpiCldmlkdplvvtpCgHvfCqkCilra 30 eCp+Cl+ lk+p ++ pC H+fC +C++r FUN_001559-T1 15 ECPLCLEILKNP-RTLPCLHSFCLECLDRQ 43 7***********.*************9874 PP == domain 2 score: -1.1 bits; conditional E-value: 2.3 zf-C3HC4_2 1 eCpiCldmlkdp 12 +C iC +++ p FUN_001559-T1 56 RCSICRTSIEIP 67 6****9888765 PP == domain 3 score: -2.4 bits; conditional E-value: 5.8 zf-C3HC4_2 15 vtpCgHvfCqkC 26 + C+ C+kC FUN_001559-T1 178 CKDCKLLICNKC 189 456666677777 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 7.0 8.5e-08 9.1e-05 2 47 .. 13 65 .. 12 66 .. 0.94 2 ? 0.3 8.9 0.84 8.9e+02 3 33 .. 102 132 .. 100 139 .. 0.77 3 ? 0.3 1.7 0.85 9e+02 17 30 .. 178 190 .. 170 198 .. 0.59 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 8.5e-08 zf-C3HC4_3 2 eeeCviClerernvvllpCgHlclCeeCaeklr........kkkkCpiCrqkie 47 e eC +Cle +n lpC H +C eC ++ ++ +C iCr++ie FUN_001559-T1 13 EAECPLCLEILKNPRTLPCLHS-FCLECLDRQAkfareqlqTSIRCSICRTSIE 65 679*******************.*******99999999999999*******996 PP == domain 2 score: 0.3 bits; conditional E-value: 0.84 zf-C3HC4_3 3 eeCviClerern.vvllpCgHlclCeeCaekl 33 + C C e++ + + C+ + lC++C e+ FUN_001559-T1 102 RVCNSCEENNPPiCYCFVCQNF-LCSSCLESH 132 6899***996651566689998.*****9987 PP == domain 3 score: 0.3 bits; conditional E-value: 0.85 zf-C3HC4_3 17 llpCgHlclCeeCa 30 + C+ l +C++C+ FUN_001559-T1 178 CKDCKLL-ICNKCS 190 3444444.555554 PP >> ANCHR-like_BBOX ANCHR-like B-box zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 2.1 1.5 1.6e+03 16 30 .. 31 45 .. 16 51 .. 0.72 2 ! 19.8 8.0 8.2e-07 0.00087 1 38 [. 103 142 .. 103 143 .. 0.93 3 ! 16.3 5.3 1.1e-05 0.011 5 32 .. 169 197 .. 162 203 .. 0.81 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.5 ANCHR-like_BBOX 16 CddlyCekCfkehhk 30 C ++C +C+ + k FUN_001559-T1 31 CLHSFCLECLDRQAK 45 667899999877665 PP == domain 2 score: 19.8 bits; conditional E-value: 8.2e-07 ANCHR-like_BBOX 1 wCdiC..nedavlrCedCddlyCekCfkehhkkkklkdHk 38 +C+ C n++ +C+ C++++C++C+++h + +++++H+ FUN_001559-T1 103 VCNSCeeNNPPICYCFVCQNFLCSSCLESHRRLRATRGHR 142 5****87799**********************999****8 PP == domain 3 score: 16.3 bits; conditional E-value: 1.1e-05 ANCHR-like_BBOX 5 Cn.edavlrCedCddlyCekCfkehhkkk 32 ++ ++++++C+dC+ l+C+kC h + FUN_001559-T1 169 HEdQPLEFYCKDCKLLICNKCSVVRHNRH 197 4669*****************99999854 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 8.1 3.2e-07 0.00035 2 44 .] 15 61 .. 14 61 .. 0.75 2 ? -0.2 7.9 1.6 1.7e+03 3 33 .. 104 132 .. 102 138 .. 0.72 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 3.2e-07 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCl.......dkwlrtsstCPlCr 44 eCp+Cle l +++++lpC H f+ eCl ++ l+ts +C +Cr FUN_001559-T1 15 ECPLCLEIL---KNPRTLPCLHSFCLECLdrqakfaREQLQTSIRCSICR 61 8*****555...6788899**********5555544333666666****9 PP == domain 2 score: -0.2 bits; conditional E-value: 1.6 zf-RING_2 3 CpiCleeleeeekvivlpCgHvfhkeCldkw 33 C C ee + + +++ + C+ +++ +Cl+ + FUN_001559-T1 104 CNSC-EENNPPICYCFV-CQNFLCSSCLESH 132 6667.555566666677.*9999****9875 PP >> TRIM_CC TRIM protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 11.0 2.1e-06 0.0023 1 102 [. 224 325 .. 224 347 .. 0.92 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 2.1e-06 TRIM_CC 1 iqerekkieelkesvesikesaqkakeeseqvFteLiqsiekaqsevlelieeeekaalsqaeglleeLeqeiaeLkkrdaeleqLsqteDhihFL 96 i + e++i++ +e + i++++++++ee++++ ++Li+ ++++++ +++ i++ +a ++q e+ l+ Le + +Lk + ++ +++ + + + L FUN_001559-T1 224 ITMYENEIKKQNELRNKIETEVKNVEEEITRTVKKLIDDLQEHERIMKDKIRKINEAQQKQHEERLDILEWNTVQLKSCVERYQSIIKRNSSNEIL 319 567799*********************************************************************************999999999 PP TRIM_CC 97 qefpsl 102 q+ ++ FUN_001559-T1 320 QSNNTI 325 986655 PP >> SdiA-regulated SdiA-regulated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.2 1.3 1.3e+03 77 118 .. 187 229 .. 182 230 .. 0.81 2 ! 13.2 0.0 4.8e-05 0.051 28 86 .. 533 591 .. 521 603 .. 0.88 3 ? -1.3 0.0 1.3 1.4e+03 40 91 .. 677 730 .. 669 732 .] 0.73 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 1.3 SdiA-regulated 77 grlaisdEreqalvvvkvdadtksleied.lkklelglkkakN 118 ++ +++ +++++ +++ a+ ++++i+d + k++ +++ +N FUN_001559-T1 187 NKCSVVRHNRHSITDIHIAAQEQKMQIADtVDKVNAEITMYEN 229 566788889999**************99867777777766665 PP == domain 2 score: 13.2 bits; conditional E-value: 4.8e-05 SdiA-regulated 28 ltydpdtktLfavtnkpeelveLskeGevlrriplkgfkdtEaieyigdgrlaisdEre 86 +++ + L+ v +++++l +s+eG+++r i k ++ +E + +++dgr++++d FUN_001559-T1 533 VAFTDIGHLLILVPGSDNKLHLMSEEGQLIRYINDKHLEQPEHLSVASDGRIIVCDLAG 591 67777778899999****************************************99655 PP == domain 3 score: -1.3 bits; conditional E-value: 1.3 SdiA-regulated 40 vtnkpeelveLskeGevlrriplkgfkd..tEaieyigdgrlaisdEreqalvv 91 ++++l ++++G++l++++ ++f++ + ++ +d++l ++d +++ ++v FUN_001559-T1 677 SDANNQRLQFFTLDGTFLHKLQGDFFSNgcPLYVTISNDDSLFVADFQKHCIIV 730 344567777889999999999999998844556888888888888888777766 PP >> Invasin_D3 Invasin, domain 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 5e-05 0.053 26 86 .. 390 453 .. 378 460 .. 0.74 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 5e-05 Invasin_D3 26 vtlkDangnpvtvsGatvtfa..tt.aGtls.avtdngdGtytatLtagttagtatvtftvnGva 86 v ++++g p ++v++ t +G+l +++d +dG yt+t t + ag v+ +vnG+ FUN_001559-T1 390 VVTRNSEGFPCYQQDDQVEVGifTPdNGELRpNIQDTKDGRYTVTYTP-QCAGRHRVQIQVNGQP 453 55556666665555566665532335997765899************9.99************65 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00023 0.24 183 246 .. 532 595 .. 507 607 .. 0.80 2 ? -1.3 0.0 1.3 1.4e+03 190 233 .. 670 715 .. 668 731 .. 0.69 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00023 Beta-prop_WDR90_POC16_2nd 183 kvafspaklkhLlvstssnkllkldaktGrllrevsevhrsacsslavsedaryllt..agdkvik 246 +vaf+ +lv s+nk l+l +++G+l+r +++ h ++ l+v++d+r ++ agdk ik FUN_001559-T1 532 SVAFTDIGHLLILVPGSDNK-LHLMSEEGQLIRYINDKHLEQPEHLSVASDGRIIVCdlAGDK-IK 595 45555444444456667777.688899**************************9985335665.45 PP == domain 2 score: -1.3 bits; conditional E-value: 1.3 Beta-prop_WDR90_POC16_2nd 190 klkhLlvstssnkllkldaktGrllrevs.evhrsacss.lavsed 233 k ++L+vs ++n+ l++ + +G l++++ + ++c+ +++s+d FUN_001559-T1 670 KYNQLIVSDANNQRLQFFTLDGTFLHKLQgDFFSNGCPLyVTISND 715 5689999999999999999999999998733455555531344444 PP >> ARGLU Arginine and glutamate-rich 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 20.1 0.0024 2.5 31 119 .. 218 304 .. 204 331 .. 0.67 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0024 ARGLU 31 eeieaeverrveearkemekevaeelekereaeleeekrkeEeerkkreelerileenkrkveEaqrkeaeerlaeleekrrlkeerqr 119 ++++ae+ + +e +k+ +e+++++e e ++ ee r + ++ +e eri++++ rk++Eaq+k++eerl le + + + + FUN_001559-T1 218 DKVNAEITMYENEIKKQ--NELRNKIETEVKNVEEEITRTVKKLIDDLQEHERIMKDKIRKINEAQQKQHEERLDILEWNTVQLKSCVE 304 46666666655555553..556677777777666666666677778899****************************977655544333 PP >> FIN1 Filaments in between nuclei protein-1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 8.8 0.0029 3.1 162 235 .. 212 283 .. 189 294 .. 0.85 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0029 FIN1 162 qreeeeedlnkvtkrntslnselekegks.sksstrkksvkfelpeddreiskelkdlkkllealierqdelesr 235 q ++ ++kv t +++e++k+++ +k++t+ k+v++e++ + +++ ++l++ +++++ i +++e +++ FUN_001559-T1 212 QIADT---VDKVNAEITMYENEIKKQNELrNKIETEVKNVEEEITRTVKKLIDDLQEHERIMKDKIRKINEAQQK 283 44444...88999999999****8777777**********************************99999986654 PP >> Mit_KHE1 Mitochondrial K+-H+ exchange-related # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 6.8 0.0049 5.2 22 95 .. 212 286 .. 191 325 .. 0.68 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0049 Mit_KHE1 22 lekssakkaekkekledkvtnkaaktwakleksekgwkkkivelgeklldripyeEwaLks.ipsesairelekk 95 + +++ k +++ ++ + ++k +++++k+e++ k+++++i+++++kl+d ++ +E ++k i + ++ ++++++ FUN_001559-T1 212 QIADTVDKVNAEITMYENEIKKQNELRNKIETEVKNVEEEITRTVKKLIDDLQEHERIMKDkIRKINEAQQKQHE 286 333344455558888888899**************************************9624432222221212 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.2 0.44 4.7e+02 30 41 .. 8 19 .. 6 21 .. 0.83 2 ? 14.5 9.6 3.6e-05 0.038 2 43 .] 16 62 .. 15 62 .. 0.92 3 ? 3.3 9.8 0.11 1.2e+02 2 32 .. 104 132 .. 103 139 .. 0.88 4 ? 0.4 6.5 0.86 9.2e+02 5 28 .. 164 189 .. 162 197 .. 0.86 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.44 zf-RING_5 30 kklleerqCpiC 41 k+l++e++Cp+C FUN_001559-T1 8 KNLKKEAECPLC 19 6677899***** PP == domain 2 score: 14.5 bits; conditional E-value: 3.6e-05 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll........eerqCpiCkk 43 C+ C + l +++ ++C H+fC eCl+++ + +C+iC++ FUN_001559-T1 16 CPLCLEIL---KNPRTLPCLHSFCLECLDRQAkfareqlqTSIRCSICRT 62 88888888...88999************************9*******96 PP == domain 3 score: 3.3 bits; conditional E-value: 0.11 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkl 32 Cn+C + +y C+ ++C +Cl FUN_001559-T1 104 CNSCEENN--PPICYCFVCQNFLCSSCLESH 132 99999999..78899999*********9865 PP == domain 4 score: 0.4 bits; conditional E-value: 0.86 zf-RING_5 5 Cfkelsktrk..fyltsCgHifCeeC 28 C+++++++++ fy C+ ++C++C FUN_001559-T1 164 CSQSHHEDQPleFYCKDCKLLICNKC 189 999997777778************** PP >> Med4 Vitamin-D-receptor interacting Mediator subunit 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 10.0 0.012 12 23 82 .. 216 278 .. 208 293 .. 0.79 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.012 Med4 23 ehqknearilqLraeveslDekikeivktLkeyekeLralp...qqenkklakiklankrevs 82 + +k++a+i+ ++e+++ e+ +i++++k++e+e+++++ ++ ++ + i++ + r+++ FUN_001559-T1 216 TVDKVNAEITMYENEIKKQNELRNKIETEVKNVEEEITRTVkklIDDLQEHERIMKDKIRKIN 278 56899************************************5443334444555555555554 PP >> TMEM120A-B TMEM120A/B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 10.0 0.0097 10 13 97 .. 205 289 .. 193 317 .. 0.87 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0097 TMEM120A-B 13 eleetakeykekleelsklqskcskeiskqkkrlkelksslkklkkkvkeeekeaveeleeelkerkaqlkemeallpkknglyl 97 +e++ ++ ++++++++ + ++ei+kq++ +++++++k+++++++++ k+ +++l+e+ + +k +++++++ k+++ l FUN_001559-T1 205 AAQEQKMQIADTVDKVNAEITMYENEIKKQNELRNKIETEVKNVEEEITRTVKKLIDDLQEHERIMKDKIRKINEAQQKQHEERL 289 5688888999999999*******************************9999**********999999999999998888766555 PP >> DUF5446 Family of unknown function (DUF5446) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 2.7 2.2 2.4e+03 35 54 .. 233 252 .. 207 259 .. 0.58 2 ? 7.4 8.0 0.0063 6.7 17 65 .. 259 307 .. 237 313 .. 0.88 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 2.2 DUF5446 35 leaEkeekinerLeliekEl 54 ++ E ++ki+ + +e+E+ FUN_001559-T1 233 KQNELRNKIETEVKNVEEEI 252 34455555555555555555 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0063 DUF5446 17 iEeelteaEksltesvraleaEkeekinerLeliekElaeLslCinell 65 ++l e E+ + +++r+ + ++++ +erL+++e +L++C+ + FUN_001559-T1 259 LIDDLQEHERIMKDKIRKINEAQQKQHEERLDILEWNTVQLKSCVERYQ 307 568999**************************************98655 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 10.5 0.015 16 53 124 .] 209 281 .. 193 283 .. 0.88 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.015 DUF1664 53 vseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsn.ikedvksvkeaveglesklkeieekQ 124 + ++a+t ++ +++i ++++++q+e+ ++i+ ev +v+e++++ +k+ ++ ++e + ++ k+++i+e Q FUN_001559-T1 209 QKMQIADTVDKVNAEITMYENEIKKQNELRNKIETEVKNVEEEITRtVKKLIDDLQEHERIMKDKIRKINEAQ 281 4567999999999*****************************9875278889*****************9877 PP >> zf-B_box_ZFPL1 ZFPL1-like, B-box zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 7.9 0.0026 2.8 3 27 .. 103 129 .. 101 135 .. 0.86 2 ? 3.2 5.0 0.12 1.3e+02 12 33 .. 175 196 .. 162 201 .. 0.85 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0026 zf-B_box_ZFPL1 3 lc.kC.krkaTklfCFehkvnVCeeCi 27 +c +C + +CF+++ + C +C+ FUN_001559-T1 103 VCnSCeENNPPICYCFVCQNFLCSSCL 129 687898999999**************8 PP == domain 2 score: 3.2 bits; conditional E-value: 0.12 zf-B_box_ZFPL1 12 klfCFehkvnVCeeCivaeHql 33 + +C +k +C++C v +H++ FUN_001559-T1 175 EFYCKDCKLLICNKCSVVRHNR 196 67*************9999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (732 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3049 (0.119358); expected 510.9 (0.02) Passed bias filter: 858 (0.0335878); expected 510.9 (0.02) Passed Vit filter: 150 (0.00587199); expected 25.5 (0.001) Passed Fwd filter: 32 (0.00125269); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 24 [number of targets reported over threshold] # CPU time: 0.47u 0.40s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 6812.33 // Query: FUN_001562-T1 [L=2101] Description: FUN_001562 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-159 517.7 28.3 3e-15 57.1 0.5 12.4 12 Ank_2 Ankyrin repeats (3 copies) 5.3e-150 479.0 57.1 3.5e-08 33.8 0.0 25.7 25 Ank Ankyrin repeat 3.8e-110 357.8 27.2 4.1e-10 40.2 0.0 18.3 20 Ank_4 Ankyrin repeats (many copies) 1.4e-94 297.9 29.6 5.7e-05 23.7 0.0 25.5 26 Ank_3 Ankyrin repeat 4.7e-87 285.4 28.1 3.1e-07 31.1 0.0 18.6 20 Ank_5 Ankyrin repeats (many copies) 5.2e-53 179.2 35.3 5.3e-06 26.7 0.0 13.5 13 Ank_KRIT1 KRIT1 ankyrin-repeats domain 6.9e-27 94.4 17.6 0.091 13.1 0.1 11.1 11 ANK_LRRK2 LRRK2 ANK repeat 3e-16 59.4 1.8 6.6e-16 58.3 1.8 1.6 1 KH_1 KH domain 4.8e-08 33.7 0.0 1.1e-07 32.5 0.0 1.5 1 SAM_1 SAM domain (Sterile alpha motif) 0.00042 20.5 0.2 0.0062 16.8 0.1 3.0 3 KH_Vigilin Vigilin KH domain 0.0038 17.5 0.1 0.012 15.9 0.1 1.9 1 KH-I_KHDC4-BBP KHDC4/BBP-like, KH-domain type I 0.0044 17.3 0.2 0.0097 16.2 0.2 1.6 1 KH_NusA_2nd NusA-like second KH domain ------ inclusion threshold ------ 0.031 14.9 0.1 0.093 13.4 0.1 1.8 1 SAM_2 SAM domain (Sterile alpha motif) 0.085 13.3 0.1 0.41 11.1 0.1 2.2 1 KH_KhpA-B KhpA/KhpB, KH domain 5.3 7.3 9.3 2.2e+02 2.1 0.1 6.3 8 ScdA_N Domain of Unknown function (DUF542) Domain annotation for each model (and alignments): >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.9 0.0 7.3e-17 1.2e-13 2 89 .. 147 238 .. 146 239 .. 0.91 2 ! 57.1 0.5 1.7e-18 3e-15 21 88 .. 234 303 .. 233 305 .. 0.95 3 ! 50.5 0.3 1.9e-16 3.2e-13 26 88 .. 306 370 .. 301 372 .. 0.90 4 ! 48.5 0.0 7.9e-16 1.3e-12 30 89 .. 376 437 .. 370 438 .. 0.90 5 ! 44.1 0.0 2e-14 3.4e-11 28 89 .. 441 501 .. 435 502 .. 0.92 6 ! 46.6 0.0 3.1e-15 5.4e-12 20 89 .. 496 567 .. 495 568 .. 0.93 7 ! 46.0 1.3 5.1e-15 8.6e-12 2 83 .. 543 628 .. 543 634 .. 0.90 8 ! 50.1 0.1 2.6e-16 4.5e-13 21 89 .. 852 923 .. 845 924 .. 0.90 9 ! 40.1 0.0 3.4e-13 5.8e-10 27 89 .. 926 990 .. 921 991 .. 0.90 10 ! 42.8 0.2 4.8e-14 8.2e-11 27 88 .. 994 1058 .. 988 1060 .. 0.87 11 ! 40.4 0.0 2.8e-13 4.7e-10 24 90 .] 1058 1128 .. 1054 1128 .. 0.89 12 ! 55.3 0.0 6e-18 1e-14 1 82 [. 1102 1186 .. 1102 1193 .. 0.94 Alignments for each domain: == domain 1 score: 51.9 bits; conditional E-value: 7.3e-17 Ank_2 2 mlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn...dnngrtaLhyAaesghleivklLlekgadinak 89 A+ +g+ ++v+ Ll eg +++ +++ge+ L lA+++g+ e++++Ll+ +a+v+ ++ +t+L+ A++ g+++ivklLl++ ad+n++ FUN_001562-T1 147 AEACLEGDVSAVRKLLeEGWSVHEPTDEGESLLSLACSAGYFELAQVLLAMNASVDdrgSKGDCTPLMEASSGGYIDIVKLLLDHTADVNSQ 238 67999***********99999987778**********************987778877667899*******99*****************87 PP == domain 2 score: 57.1 bits; conditional E-value: 1.7e-18 Ank_2 21 danlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadina 88 d+n+q++ g+taL++A++ g++++v +Ll+hgad++ ++ng+t+L+ Aa+ gh++++k+Lle+ga in+ FUN_001562-T1 234 DVNSQSQAGNTALIYACCGGYEDVVAVLLSHGADIEahNENGHTPLMEAASGGHVNVAKMLLERGACINS 303 8899999*************************9999999***********99**************9996 PP == domain 3 score: 50.5 bits; conditional E-value: 1.9e-16 Ank_2 26 dkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadina 88 ++++e+aL lA+++ghle+vk+Ll+ gad++ +++ +taL+ A++ gh+e+++lLl++ga++n FUN_001562-T1 306 NEFKESALTLACYKGHLEMVKFLLDAGADQEhkTDEMHTALMEASMDGHVEVARLLLDHGAQVNM 370 4589*********************9999999878899************************996 PP == domain 4 score: 48.5 bits; conditional E-value: 7.9e-16 Ank_2 30 etaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 e++L lAa+ gh+e++ lL++ ga ++ +++g+t+L+ A+++ghl++v lLle+gadi+a+ FUN_001562-T1 376 ESPLTLAACGGHVELADLLIKRGAFLEevNDEGYTPLMEASREGHLDMVALLLEHGADIHAQ 437 68*******************986555566*****************************986 PP == domain 5 score: 44.1 bits; conditional E-value: 2e-14 Ank_2 28 ngetaLhlAaknghleivklLlehgadvndnngrtaLhyAaesghleivklLlekgadinak 89 + etaL lA++ g ++++ +Ll+ ga+++ + t+L+ Aa++gh++ vk+Lle+ga++na+ FUN_001562-T1 441 TQETALSLACCGGFQDVAAFLLQAGASIE-QGSSTPLMEAAQEGHVDLVKFLLERGANVNAT 501 679********************999999.9999**************************86 PP == domain 6 score: 46.6 bits; conditional E-value: 3.1e-15 Ank_2 20 adanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 a++n ++ +g+t+L +A++ngh++++ +Ll+ gad++ ++ grt+ + Aa+ ghl +v++L+++ga++n + FUN_001562-T1 496 ANVNATTATGDTPLSFACENGHTDVADVLLSAGADLEheSEAGRTPVMKAARAGHLCTVQFLISRGASVNHQ 567 67788888***********************99999987788**********************9****987 PP == domain 7 score: 46.0 bits; conditional E-value: 5.1e-15 Ank_2 2 mlAakngnlelvklLl.egadanlqdk.ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekg 83 m Aa+ g+l +v++L+ ga++n+q++ n +t+L lA+ ghl +v+lLl+hgad +++ ++L+ Aa+ gh ++ +Lle+ FUN_001562-T1 543 MKAARAGHLCTVQFLIsRGASVNHQTTmNDHTVLSLACAGGHLAVVELLLAHGADPLhkLKDNSNILIEAAKGGHAAVICFLLENP 628 78*********************9888999**********************9873345477899******************874 PP == domain 8 score: 50.1 bits; conditional E-value: 2.6e-16 Ank_2 21 danlqdk.ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 d+++q++ n +taL lA gh e+v lLl +gad++ d++g+t+L++Aa gh +v++Ll++gadi+a+ FUN_001562-T1 852 DVDQQTDsNSDTALTLASAGGHDELVTLLLVKGADIEhrDKKGCTPLILAATAGHASTVEILLDHGADIEAQ 923 5664444599**********************99999999*****************************986 PP == domain 9 score: 40.1 bits; conditional E-value: 3.4e-13 Ank_2 27 kngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 +++taL lA++ g++e+v+lL++++a+ + + + +t+L +Aa+ g++ i++lLl + a+in++ FUN_001562-T1 926 RTKDTALSLACSGGRQEVVELLISKEANFEhrNVSDYTPLSLAASGGYVGIIQLLLRHRAEINSR 990 4679********************99887788899*********99**********99****986 PP == domain 10 score: 42.8 bits; conditional E-value: 4.8e-14 Ank_2 27 kngetaLhlAaknghleivklLlehgadvn...dnngrtaLhyAaesghleivklLlekgadina 88 k g ++L+lA +ngh +vklLl+ g d+n + n++taL +A+ +g++e+v lL+e+ a+i+ FUN_001562-T1 994 KLGISPLMLASMNGHSAAVKLLLDMGSDINaqiETNKNTALTLACFQGRHEVVSLLVERRANIEH 1058 47899*******************885655557799*********************99999876 PP == domain 11 score: 40.4 bits; conditional E-value: 2.8e-13 Ank_2 24 lqdkngetaLhlAaknghleivklLlehgadvn....dnngrtaLhyAaesghleivklLlekgadinakd 90 ++ k+g t+L+ Aa+ g++e+ ++Ll++g dvn +++ taL +Aa +gh++ + lLl++ga +++k+ FUN_001562-T1 1058 HRAKTGLTPLMEAASGGYVEVGRILLDKGGDVNalpvPSSKDTALTIAADKGHYKFCDLLLSRGAVVDVKN 1128 344599**********************988888888899*********************99*9998875 PP == domain 12 score: 55.3 bits; conditional E-value: 6e-18 Ank_2 1 LmlAakngnlelvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlek 82 L +Aa +g++++++lLl ga +++++k+g+++L+lAa+ ghle+++lL ++gadv+ dn + + L+ A ++gh++++k+L+++ FUN_001562-T1 1102 LTIAADKGHYKFCDLLLsRGAVVDVKNKKGNSPLWLAANGGHLEVCQLLFSYGADVDsqDNRKVSVLMAAFRKGHIKVIKWLVKH 1186 679***************9*99*******************************999999999*********************65 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.25 4.3e+02 9 30 .. 149 170 .. 145 173 .. 0.83 2 ! 10.9 0.0 0.0004 0.68 2 31 .. 175 204 .. 174 206 .. 0.89 3 ! 24.5 0.0 1.8e-08 3.1e-05 3 31 .. 210 238 .. 208 240 .. 0.91 4 ! 26.2 0.3 5.3e-09 9.1e-06 2 32 .. 242 272 .. 241 273 .. 0.94 5 ! 28.9 0.2 7.2e-10 1.2e-06 1 30 [. 274 303 .. 274 306 .. 0.93 6 ! 21.1 0.0 2.2e-07 0.00038 4 31 .. 311 338 .. 309 340 .. 0.87 7 ! 22.3 0.2 9.4e-08 0.00016 3 30 .. 343 370 .. 342 373 .. 0.93 8 ! 14.2 0.0 3.5e-05 0.06 4 28 .. 377 401 .. 376 406 .. 0.85 9 ! 33.8 0.0 2.1e-11 3.5e-08 2 32 .. 408 438 .. 407 439 .. 0.95 10 ! 13.3 0.0 6.9e-05 0.12 3 29 .. 443 469 .. 441 473 .. 0.91 11 ! 33.0 0.0 3.7e-11 6.3e-08 4 32 .. 474 502 .. 471 503 .. 0.94 12 ! 22.5 0.0 8e-08 0.00014 2 29 .. 505 532 .. 504 535 .. 0.92 13 ! 22.4 0.0 8.6e-08 0.00015 2 32 .. 538 568 .. 537 569 .. 0.94 14 ! 19.5 1.5 7.3e-07 0.0012 2 30 .. 572 600 .. 571 603 .. 0.90 15 ? 3.9 0.0 0.066 1.1e+02 5 24 .. 608 627 .. 604 634 .. 0.79 16 ! 19.0 0.1 1.1e-06 0.0018 3 33 .] 862 892 .. 860 892 .. 0.92 17 ! 28.1 0.1 1.3e-09 2.3e-06 2 32 .. 894 924 .. 893 925 .. 0.93 18 ! 15.8 0.0 1.1e-05 0.019 3 32 .. 929 958 .. 927 959 .. 0.88 19 ! 20.1 0.0 4.6e-07 0.00078 3 32 .. 962 991 .. 960 992 .. 0.93 20 ! 22.6 0.1 7.4e-08 0.00013 2 31 .. 996 1025 .. 995 1026 .. 0.94 21 ! 18.4 0.0 1.7e-06 0.0028 1 31 [. 1029 1059 .. 1029 1061 .. 0.89 22 ! 19.8 0.0 5.9e-07 0.001 2 30 .. 1063 1091 .. 1062 1092 .. 0.94 23 ! 17.8 0.0 2.5e-06 0.0042 3 33 .] 1099 1129 .. 1097 1129 .. 0.93 24 ! 29.2 0.0 5.7e-10 9.7e-07 2 33 .] 1131 1162 .. 1130 1162 .. 0.95 25 ? 5.7 0.1 0.018 30 6 24 .. 1168 1186 .. 1165 1189 .. 0.82 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.25 Ank 9 AaraghlevvklLLkhGAdvna 30 A+ +g+++ v+ LL++G +v+ FUN_001562-T1 149 ACLEGDVSAVRKLLEEGWSVHE 170 8989**********87988775 PP == domain 2 score: 10.9 bits; conditional E-value: 0.0004 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnar 31 G + L lA++ag+ e+++ LL +A+v+ r FUN_001562-T1 175 GESLLSLACSAGYFELAQVLLAMNASVDDR 204 8999*****************659**9977 PP == domain 3 score: 24.5 bits; conditional E-value: 1.8e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnar 31 +TPL+ A++ g++++vklLL+h Advn + FUN_001562-T1 210 CTPLMEASSGGYIDIVKLLLDHTADVNSQ 238 8*******************878****87 PP == domain 4 score: 26.2 bits; conditional E-value: 5.3e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 GnT+L +A++ g+++vv LL+hGAd+ a + FUN_001562-T1 242 GNTALIYACCGGYEDVVAVLLSHGADIEAHN 272 9********************99****9977 PP == domain 5 score: 28.9 bits; conditional E-value: 7.2e-10 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvna 30 +G+TPL+ Aa+ gh++v+k+LL++GA +n FUN_001562-T1 274 NGHTPLMEAASGGHVNVAKMLLERGACINS 303 8*********************88****97 PP == domain 6 score: 21.1 bits; conditional E-value: 2.2e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvnar 31 ++L lA+++ghle+vk+LL++GAd + FUN_001562-T1 311 SALTLACYKGHLEMVKFLLDAGADQEHK 338 79*****99**********88**97655 PP == domain 7 score: 22.3 bits; conditional E-value: 9.4e-08 Ank 3 nTPLHlAaraghlevvklLLkhGAdvna 30 +T+L+ A++ gh+ev++lLL+hGA vn FUN_001562-T1 343 HTALMEASMDGHVEVARLLLDHGAQVNM 370 6*******************99****97 PP == domain 8 score: 14.2 bits; conditional E-value: 3.5e-05 Ank 4 TPLHlAaraghlevvklLLkhGAdv 28 +PL lAa+ gh+e++ lL+k+GA + FUN_001562-T1 377 SPLTLAACGGHVELADLLIKRGAFL 401 7******************889955 PP == domain 9 score: 33.8 bits; conditional E-value: 2.1e-11 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+TPL+ A+r+ghl++v lLL+hGAd++a++ FUN_001562-T1 408 GYTPLMEASREGHLDMVALLLEHGADIHAQT 438 9********************99*****997 PP == domain 10 score: 13.3 bits; conditional E-value: 6.9e-05 Ank 3 nTPLHlAaraghlevvklLLkhGAdvn 29 T+L lA++ g +v+ +LL++GA++ FUN_001562-T1 443 ETALSLACCGGFQDVAAFLLQAGASIE 469 6*******9999********98**986 PP == domain 11 score: 33.0 bits; conditional E-value: 3.7e-11 Ank 4 TPLHlAaraghlevvklLLkhGAdvnard 32 TPL+ Aa++gh+++vk+LL++GA+vna++ FUN_001562-T1 474 TPLMEAAQEGHVDLVKFLLERGANVNATT 502 *******************88*****987 PP == domain 12 score: 22.5 bits; conditional E-value: 8e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvn 29 G+TPL A+++gh++v+ LL++GAd+ FUN_001562-T1 505 GDTPLSFACENGHTDVADVLLSAGADLE 532 9********************88***85 PP == domain 13 score: 22.4 bits; conditional E-value: 8.6e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+TP + Aaraghl +v++L+++GA+vn ++ FUN_001562-T1 538 GRTPVMKAARAGHLCTVQFLISRGASVNHQT 568 9********************88*****986 PP == domain 14 score: 19.5 bits; conditional E-value: 7.3e-07 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvna 30 +T L lA+ ghl vv+lLL hGAd+ FUN_001562-T1 572 DHTVLSLACAGGHLAVVELLLAHGADPLH 600 689******************88***965 PP == domain 15 score: 3.9 bits; conditional E-value: 0.066 Ank 5 PLHlAaraghlevvklLLkh 24 L Aa+ gh v+ +LL++ FUN_001562-T1 608 ILIEAAKGGHAAVICFLLEN 627 6889**************63 PP == domain 16 score: 19.0 bits; conditional E-value: 1.1e-06 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnardk 33 +T+L lA+ gh e+v lLL +GAd+ rdk FUN_001562-T1 862 DTALTLASAGGHDELVTLLLVKGADIEHRDK 892 7*******************66*****9997 PP == domain 17 score: 28.1 bits; conditional E-value: 1.3e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+TPL lAa agh ++v++LL+hGAd+ a+ FUN_001562-T1 894 GCTPLILAATAGHASTVEILLDHGADIEAQS 924 9********9***********99****9975 PP == domain 18 score: 15.8 bits; conditional E-value: 1.1e-05 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +T+L lA++ g+ evv+lL+++ A+ r+ FUN_001562-T1 929 DTALSLACSGGRQEVVELLISKEANFEHRN 958 7*******************7689987776 PP == domain 19 score: 20.1 bits; conditional E-value: 4.6e-07 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPL lAa+ g++ +++lLL+h A +n r+ FUN_001562-T1 962 YTPLSLAASGGYVGIIQLLLRHRAEINSRT 991 8*******************989****986 PP == domain 20 score: 22.6 bits; conditional E-value: 7.4e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnar 31 G +PL+lA+++gh vklLL+ G d+na+ FUN_001562-T1 996 GISPLMLASMNGHSAAVKLLLDMGSDINAQ 1025 889******************77*****96 PP == domain 21 score: 18.4 bits; conditional E-value: 1.7e-06 Ank 1 dGnTPLHlAaraghlevvklLLkhGAdvnar 31 + nT+L lA+ g++evv lL+++ A++ r FUN_001562-T1 1029 NKNTALTLACFQGRHEVVSLLVERRANIEHR 1059 569*******99**********889**9876 PP == domain 22 score: 19.8 bits; conditional E-value: 5.9e-07 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvna 30 G TPL+ Aa+ g++ev ++LL++G dvna FUN_001562-T1 1063 GLTPLMEAASGGYVEVGRILLDKGGDVNA 1091 99*******************8799***8 PP == domain 23 score: 17.8 bits; conditional E-value: 2.5e-06 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnardk 33 +T+L +Aa +gh++ + lLL++GA v++++k FUN_001562-T1 1099 DTALTIAADKGHYKFCDLLLSRGAVVDVKNK 1129 7*******99**********88******996 PP == domain 24 score: 29.2 bits; conditional E-value: 5.7e-10 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 Gn+PL+lAa+ ghlev++lL ++GAdv+ +d+ FUN_001562-T1 1131 GNSPLWLAANGGHLEVCQLLFSYGADVDSQDN 1162 9********************88*******97 PP == domain 25 score: 5.7 bits; conditional E-value: 0.018 Ank 6 LHlAaraghlevvklLLkh 24 L++A r+gh++v+k+L+kh FUN_001562-T1 1168 LMAAFRKGHIKVIKWLVKH 1186 666669**********964 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 4.2e-07 0.00072 3 50 .] 148 195 .. 146 195 .. 0.95 2 ! 26.1 0.0 6.4e-09 1.1e-05 3 50 .] 181 229 .. 179 229 .. 0.96 3 ! 25.4 0.0 1e-08 1.8e-05 3 48 .. 215 260 .. 213 261 .. 0.91 4 ! 30.8 0.0 2.2e-10 3.7e-07 8 50 .] 253 295 .. 252 295 .. 0.97 5 ! 19.7 0.0 6.8e-07 0.0012 14 50 .] 292 329 .. 292 329 .. 0.93 6 ! 32.2 0.0 7.5e-11 1.3e-07 2 50 .] 347 395 .. 342 395 .. 0.93 7 ! 29.4 0.1 5.7e-10 9.8e-07 5 50 .] 383 428 .. 379 428 .. 0.92 8 ! 24.8 0.1 1.6e-08 2.7e-05 3 50 .] 414 462 .. 412 462 .. 0.90 9 ! 40.2 0.0 2.4e-13 4.1e-10 2 50 .] 477 525 .. 476 525 .. 0.96 10 ! 23.8 0.0 3.3e-08 5.5e-05 3 50 .] 511 558 .. 510 558 .. 0.96 11 ! 22.6 0.1 8.3e-08 0.00014 3 50 .] 544 592 .. 542 592 .. 0.96 12 ! 21.9 0.6 1.3e-07 0.00022 3 50 .] 578 625 .. 576 625 .. 0.95 13 ! 7.6 0.0 0.0042 7.2 21 50 .] 851 881 .. 850 881 .. 0.91 14 ! 25.6 0.0 9.3e-09 1.6e-05 3 50 .] 867 914 .. 865 914 .. 0.94 15 ! 25.5 0.0 9.8e-09 1.7e-05 4 50 .] 901 948 .. 900 948 .. 0.97 16 ! 23.4 0.0 4.4e-08 7.5e-05 3 50 .] 934 981 .. 932 981 .. 0.96 17 ! 30.9 0.1 2e-10 3.4e-07 3 50 .] 1002 1050 .. 1000 1050 .. 0.95 18 ! 18.9 0.0 1.2e-06 0.0021 2 45 .. 1035 1078 .. 1034 1078 .. 0.95 19 ! 21.9 0.0 1.4e-07 0.00023 2 50 .] 1068 1118 .. 1067 1118 .. 0.96 20 ! 31.7 0.0 1.1e-10 1.8e-07 2 50 .] 1136 1184 .. 1135 1184 .. 0.95 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 4.2e-07 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 A+ +g++ +++ Lle g+++++ ++ge+ L A+s g++e ++ Ll FUN_001562-T1 148 EACLEGDVSAVRKLLEEGWSVHEPTDEGESLLSLACSAGYFELAQVLL 195 5899********************999******************997 PP == domain 2 score: 26.1 bits; conditional E-value: 6.4e-09 Ank_4 3 aAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 A+++g +el++ Ll+ a+++++ + + t+L A+s+g+++++klLl FUN_001562-T1 181 LACSAGYFELAQVLLAMNASVDDRgSKGDCTPLMEASSGGYIDIVKLLL 229 599*********************************************7 PP == domain 3 score: 25.4 bits; conditional E-value: 1e-08 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAasngnlevlkl 48 A + g ++++klLl++ ad+n + g+taL +A+ +g+ +v+ FUN_001562-T1 215 EASSGGYIDIVKLLLDHTADVNSQSQAGNTALIYACCGGYEDVVAV 260 68889*******************999************9999865 PP == domain 4 score: 30.8 bits; conditional E-value: 2.2e-10 Ank_4 8 ghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 g ++++ Ll++gadi a ++ng t+L Aas+g+++v+k+Ll FUN_001562-T1 253 GYEDVVAVLLSHGADIEAHNENGHTPLMEAASGGHVNVAKMLL 295 789***************************************8 PP == domain 5 score: 19.7 bits; conditional E-value: 6.8e-07 Ank_4 14 klLlengadinat.dgngetaLhfAasngnlevlklLl 50 k+Lle ga in +++ e+aL+ A+++g+le++k+Ll FUN_001562-T1 292 KMLLERGACINSHsNEFKESALTLACYKGHLEMVKFLL 329 68999999888889***********************8 PP == domain 6 score: 32.2 bits; conditional E-value: 7.5e-11 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 A ++gh+e+++lLl++ga++n+ ++ e++L+ Aa +g++e + lL+ FUN_001562-T1 347 MEASMDGHVEVARLLLDHGAQVNMPADSFESPLTLAACGGHVELADLLI 395 56888********************778*******************98 PP == domain 7 score: 29.4 bits; conditional E-value: 5.7e-10 Ank_4 5 aksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 a gh+el++lL++ ga + +++++g+t+L A++ g+l+++ lLl FUN_001562-T1 383 ACGGHVELADLLIKRGAFLEEVNDEGYTPLMEASREGHLDMVALLL 428 448***************************************9997 PP == domain 8 score: 24.8 bits; conditional E-value: 1.6e-08 Ank_4 3 aAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 A +ghl+++ lLle+gadi+a+ + +etaL A+ +g +v+ +Ll FUN_001562-T1 414 EASREGHLDMVALLLEHGADIHAQtEETQETALSLACCGGFQDVAAFLL 462 68889*******************9999********9999888888776 PP == domain 9 score: 40.2 bits; conditional E-value: 2.4e-13 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 Aa +gh++l+k+Lle ga++nat g+t+L fA+ ng+++v+ Ll FUN_001562-T1 477 MEAAQEGHVDLVKFLLERGANVNATTATGDTPLSFACENGHTDVADVLL 525 679******************************************9997 PP == domain 10 score: 23.8 bits; conditional E-value: 3.3e-08 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 +A++ gh+++++ Ll+ gad+ + + g+t++ +Aa+ g+l +++L+ FUN_001562-T1 511 FACENGHTDVADVLLSAGADLEHESEAGRTPVMKAARAGHLCTVQFLI 558 69******************99999*********************98 PP == domain 11 score: 22.6 bits; conditional E-value: 8.3e-08 Ank_4 3 aAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 +Aa +ghl ++++L++ ga++n++ n+ t+L A+++g+l v++lLl FUN_001562-T1 544 KAARAGHLCTVQFLISRGASVNHQtTMNDHTVLSLACAGGHLAVVELLL 592 7999*********************999*******************97 PP == domain 12 score: 21.9 bits; conditional E-value: 1.3e-07 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 A++ ghl +++lLl++gad+ + ++ + L Aa++g+ v+++Ll FUN_001562-T1 578 LACAGGHLAVVELLLAHGADPLHKLKDNSNILIEAAKGGHAAVICFLL 625 5999********************999********************7 PP == domain 13 score: 7.6 bits; conditional E-value: 0.0042 Ank_4 21 adinat.dgngetaLhfAasngnlevlklLl 50 +d++ + d n +taL+ A+++g+ e + lLl FUN_001562-T1 851 IDVDQQtDSNSDTALTLASAGGHDELVTLLL 881 5889999****************99998886 PP == domain 14 score: 25.6 bits; conditional E-value: 9.3e-09 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 A + gh el+ lLl +gadi ++d+ g t+L Aa g+ + ++ Ll FUN_001562-T1 867 LASAGGHDELVTLLLVKGADIEHRDKKGCTPLILAATAGHASTVEILL 914 57789*************************************999997 PP == domain 15 score: 25.5 bits; conditional E-value: 9.8e-09 Ank_4 4 AaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 Aa +gh +++ Ll++gadi a+ d+ +taL A+s+g+ ev++lL+ FUN_001562-T1 901 AATAGHASTVEILLDHGADIEAQsDRTKDTALSLACSGGRQEVVELLI 948 8899******************************************98 PP == domain 16 score: 23.4 bits; conditional E-value: 4.4e-08 Ank_4 3 aAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 A++ g++e+++lL+++ a++ +++ +++t+L Aas+g++ +++lLl FUN_001562-T1 934 LACSGGRQEVVELLISKEANFEHRNVSDYTPLSLAASGGYVGIIQLLL 981 5999*******************************************7 PP == domain 17 score: 30.9 bits; conditional E-value: 2e-10 Ank_4 3 aAaksghlellklLlengadinat.dgngetaLhfAasngnlevlklLl 50 A + gh ++klLl+ g dina+ n +taL+ A++ g+ ev++lL+ FUN_001562-T1 1002 LASMNGHSAAVKLLLDMGSDINAQiETNKNTALTLACFQGRHEVVSLLV 1050 5889******************************************996 PP == domain 18 score: 18.9 bits; conditional E-value: 1.2e-06 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlev 45 + A+ +g+ e++ lL+e +a+i ++ + g t+L Aas+g++ev FUN_001562-T1 1035 TLACFQGRHEVVSLLVERRANIEHRAKTGLTPLMEAASGGYVEV 1078 56999************************************986 PP == domain 19 score: 21.9 bits; conditional E-value: 1.4e-07 Ank_4 2 haAaksghlellklLlengadinat..dgngetaLhfAasngnlevlklLl 50 Aa+ g +e+ + Ll++g d+na+ + + +taL++Aa +g+++++ lLl FUN_001562-T1 1068 MEAASGGYVEVGRILLDKGGDVNALpvPSSKDTALTIAADKGHYKFCDLLL 1118 679**********************999********************997 PP == domain 20 score: 31.7 bits; conditional E-value: 1.1e-10 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 + Aa ghle+++lL+++gad++ +d+ ++L A ++g+++v+k+L+ FUN_001562-T1 1136 WLAANGGHLEVCQLLFSYGADVDSQDNRKVSVLMAAFRKGHIKVIKWLV 1184 66899********************999********************6 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.63 1.1e+03 6 29 .. 146 168 .. 142 170 .. 0.83 2 ! 10.1 0.0 0.00088 1.5 1 30 [. 174 202 .. 174 203 .. 0.93 3 ! 13.7 0.0 6e-05 0.1 3 30 .. 210 236 .. 208 237 .. 0.95 4 ! 9.2 0.1 0.0018 3.1 2 30 .. 242 269 .. 241 270 .. 0.95 5 ! 14.7 0.0 2.8e-05 0.047 1 27 [. 274 299 .. 274 303 .. 0.92 6 ! 15.7 0.0 1.3e-05 0.023 3 28 .. 310 334 .. 308 337 .. 0.91 7 ! 14.2 0.0 4e-05 0.069 3 31 .] 343 370 .. 341 370 .. 0.93 8 ? 2.7 0.0 0.23 3.9e+02 3 27 .. 376 399 .. 375 399 .. 0.92 9 ! 23.7 0.0 3.4e-08 5.7e-05 1 31 [] 407 436 .. 407 436 .. 0.95 10 ? -0.5 0.0 2.7 4.5e+03 3 29 .. 443 468 .. 441 470 .. 0.85 11 ! 20.1 0.0 5.1e-07 0.00086 4 31 .] 474 500 .. 472 500 .. 0.96 12 ! 18.3 0.0 1.8e-06 0.0031 2 30 .. 505 532 .. 504 533 .. 0.94 13 ! 14.3 0.0 3.8e-05 0.065 2 31 .] 538 566 .. 537 566 .. 0.96 14 ! 14.5 0.3 3.4e-05 0.057 3 30 .. 573 599 .. 571 600 .. 0.92 15 ? 3.2 0.1 0.16 2.7e+02 4 25 .. 607 628 .. 604 632 .. 0.82 16 ? 5.2 0.0 0.035 60 4 30 .. 863 888 .. 860 889 .. 0.90 17 ! 13.5 0.0 7e-05 0.12 2 30 .. 894 921 .. 893 922 .. 0.94 18 ! 7.5 0.0 0.0062 11 3 29 .. 929 954 .. 927 956 .. 0.89 19 ! 11.8 0.0 0.00025 0.42 3 30 .. 962 988 .. 960 989 .. 0.95 20 ! 19.8 0.1 5.9e-07 0.001 2 31 .] 996 1024 .. 995 1024 .. 0.96 21 ! 14.1 0.0 4.3e-05 0.074 2 30 .. 1030 1057 .. 1029 1058 .. 0.92 22 ! 12.3 0.0 0.00017 0.3 2 31 .] 1063 1091 .. 1062 1091 .. 0.95 23 ? 6.8 0.0 0.011 18 4 29 .. 1100 1124 .. 1098 1126 .. 0.89 24 ! 17.1 0.0 4.8e-06 0.0082 2 30 .. 1131 1158 .. 1130 1159 .. 0.93 25 ? 4.3 0.0 0.07 1.2e+02 4 24 .. 1166 1186 .. 1163 1190 .. 0.89 26 ? -2.2 0.0 9.3 1.6e+04 15 30 .. 1497 1512 .. 1493 1513 .. 0.86 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.63 Ank_3 6 LhlAarngrleivklLleklgadi 29 L A++ g++ +v+ Lle g ++ FUN_001562-T1 146 LAEACLEGDVSAVRKLLE-EGWSV 168 667**************9.67665 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00088 Ank_3 1 dgntpLhlAarngrleivklLleklgadin 30 +g+++L lA++ g +e++++Ll ++a+++ FUN_001562-T1 174 EGESLLSLACSAGYFELAQVLLA-MNASVD 202 599********************.999876 PP == domain 3 score: 13.7 bits; conditional E-value: 6e-05 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +tpL+ A + g ++ivklLl+ + ad+n FUN_001562-T1 210 CTPLMEASSGGYIDIVKLLLD-HTADVN 236 7********************.****98 PP == domain 4 score: 9.2 bits; conditional E-value: 0.0018 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 gnt+L +A+ g ++v +Ll +gadi FUN_001562-T1 242 GNTALIYACCGGYEDVVAVLLS-HGADIE 269 9*********************.****97 PP == domain 5 score: 14.7 bits; conditional E-value: 2.8e-05 Ank_3 1 dgntpLhlAarngrleivklLleklga 27 +g tpL+ Aa+ g++ ++k+Lle +ga FUN_001562-T1 274 NGHTPLMEAASGGHVNVAKMLLE-RGA 299 699********************.887 PP == domain 6 score: 15.7 bits; conditional E-value: 1.3e-05 Ank_3 3 ntpLhlAarngrleivklLleklgad 28 +++L lA+ g+le+vk+Ll+ gad FUN_001562-T1 310 ESALTLACYKGHLEMVKFLLD-AGAD 334 799******************.9998 PP == domain 7 score: 14.2 bits; conditional E-value: 4e-05 Ank_3 3 ntpLhlAarngrleivklLleklgadina 31 t+L+ A + g++e+++lLl+ +ga +n+ FUN_001562-T1 343 HTALMEASMDGHVEVARLLLD-HGAQVNM 370 69*******************.***9985 PP == domain 8 score: 2.7 bits; conditional E-value: 0.23 Ank_3 3 ntpLhlAarngrleivklLleklga 27 ++pL lAa g++e+++lL++ +ga FUN_001562-T1 376 ESPLTLAACGGHVELADLLIK-RGA 399 589******************.886 PP == domain 9 score: 23.7 bits; conditional E-value: 3.4e-08 Ank_3 1 dgntpLhlAarngrleivklLleklgadina 31 +g+tpL+ A r g+l++v lLle +gadi+a FUN_001562-T1 407 EGYTPLMEASREGHLDMVALLLE-HGADIHA 436 59*********************.*****85 PP == domain 10 score: -0.5 bits; conditional E-value: 2.7 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 +t+L lA+ g +++ +Ll+ ga+i FUN_001562-T1 443 ETALSLACCGGFQDVAAFLLQ-AGASI 468 799999999999999999999.89987 PP == domain 11 score: 20.1 bits; conditional E-value: 5.1e-07 Ank_3 4 tpLhlAarngrleivklLleklgadina 31 tpL+ Aa g++++vk+Lle +ga++na FUN_001562-T1 474 TPLMEAAQEGHVDLVKFLLE-RGANVNA 500 9*******************.*****96 PP == domain 12 score: 18.3 bits; conditional E-value: 1.8e-06 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 g tpL +A++ng+ +++++Ll gad+ FUN_001562-T1 505 GDTPLSFACENGHTDVADVLLS-AGADLE 532 89********************.9***86 PP == domain 13 score: 14.3 bits; conditional E-value: 3.8e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+tp + Aar g+l v++L+ +ga++n+ FUN_001562-T1 538 GRTPVMKAARAGHLCTVQFLIS-RGASVNH 566 9*************99******.****996 PP == domain 14 score: 14.5 bits; conditional E-value: 3.4e-05 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 t L lA+ g+l +v+lLl +gad+ FUN_001562-T1 573 HTVLSLACAGGHLAVVELLLA-HGADPL 599 699******************.****86 PP == domain 15 score: 3.2 bits; conditional E-value: 0.16 Ank_3 4 tpLhlAarngrleivklLlekl 25 ++L Aa+ g+ ++++Lle++ FUN_001562-T1 607 NILIEAAKGGHAAVICFLLENP 628 67889***************54 PP == domain 16 score: 5.2 bits; conditional E-value: 0.035 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 t+L lA g+ e+v lLl +gadi FUN_001562-T1 863 TALTLASAGGHDELVTLLLV-KGADIE 888 9************9999999.9***97 PP == domain 17 score: 13.5 bits; conditional E-value: 7e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 g+tpL lAa g+ v+ Ll+ +gadi FUN_001562-T1 894 GCTPLILAATAGHASTVEILLD-HGADIE 921 99************99******.****97 PP == domain 18 score: 7.5 bits; conditional E-value: 0.0062 Ank_3 3 ntpLhlAarngrleivklLleklgadi 29 t+L lA++ gr e+v+lL+ + a++ FUN_001562-T1 929 DTALSLACSGGRQEVVELLIS-KEANF 954 59******************9.88876 PP == domain 19 score: 11.8 bits; conditional E-value: 0.00025 Ank_3 3 ntpLhlAarngrleivklLleklgadin 30 +tpL lAa+ g + i++lLl+ + a+in FUN_001562-T1 962 YTPLSLAASGGYVGIIQLLLR-HRAEIN 988 8********************.999998 PP == domain 20 score: 19.8 bits; conditional E-value: 5.9e-07 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g +pL+lA +ng+ +vklLl+ +g dina FUN_001562-T1 996 GISPLMLASMNGHSAAVKLLLD-MGSDINA 1024 89********************.*****96 PP == domain 21 score: 14.1 bits; conditional E-value: 4.3e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 nt+L lA+ gr+e+v lL+e + a+i FUN_001562-T1 1030 KNTALTLACFQGRHEVVSLLVE-RRANIE 1057 69********************.999986 PP == domain 22 score: 12.3 bits; conditional E-value: 0.00017 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g tpL+ Aa+ g +e+ + Ll+ +g d+na FUN_001562-T1 1063 GLTPLMEAASGGYVEVGRILLD-KGGDVNA 1091 89********************.****996 PP == domain 23 score: 6.8 bits; conditional E-value: 0.011 Ank_3 4 tpLhlAarngrleivklLleklgadi 29 t+L +Aa g+++ ++lLl +ga + FUN_001562-T1 1100 TALTIAADKGHYKFCDLLLS-RGAVV 1124 9******************9.99865 PP == domain 24 score: 17.1 bits; conditional E-value: 4.8e-06 Ank_3 2 gntpLhlAarngrleivklLleklgadin 30 gn+pL lAa g+le+++lL+ +gad++ FUN_001562-T1 1131 GNSPLWLAANGGHLEVCQLLFS-YGADVD 1158 9**************9999999.****97 PP == domain 25 score: 4.3 bits; conditional E-value: 0.07 Ank_3 4 tpLhlAarngrleivklLlek 24 + L+ A r g+++++k+L+++ FUN_001562-T1 1166 SVLMAAFRKGHIKVIKWLVKH 1186 6899999************94 PP == domain 26 score: -2.2 bits; conditional E-value: 9.3 Ank_3 15 leivklLleklgadin 30 ++++++L++ + +din FUN_001562-T1 1497 HQLIQALVKDPECDIN 1512 5689*****999*998 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 2.4e-06 0.004 1 53 [. 161 213 .. 161 213 .. 0.93 2 ! 22.1 0.0 1.2e-07 0.00021 14 56 .] 209 249 .. 199 249 .. 0.91 3 ! 21.4 0.2 2e-07 0.00035 1 40 [. 261 299 .. 261 305 .. 0.91 4 ! 20.4 0.0 4.1e-07 0.0007 11 53 .. 304 346 .. 301 346 .. 0.89 5 ! 13.3 0.0 7.1e-05 0.12 18 56 .] 344 382 .. 332 382 .. 0.89 6 ! 31.0 0.0 1.9e-10 3.3e-07 13 56 .] 405 449 .. 386 449 .. 0.94 7 ! 31.1 0.0 1.8e-10 3.1e-07 1 56 [] 461 512 .. 461 512 .. 0.86 8 ! 10.6 0.0 0.00051 0.87 18 41 .. 507 530 .. 504 531 .. 0.85 9 ! 12.1 0.0 0.00017 0.29 1 47 [. 524 569 .. 524 573 .. 0.88 10 ! 17.8 0.3 2.7e-06 0.0046 1 42 [. 557 598 .. 557 601 .. 0.91 11 ! 9.3 0.1 0.0013 2.2 16 41 .. 605 630 .. 599 634 .. 0.84 12 ! 16.9 0.0 5.4e-06 0.0092 13 56 .] 858 901 .. 851 901 .. 0.89 13 ! 30.8 0.0 2.2e-10 3.8e-07 1 56 [] 880 935 .. 880 935 .. 0.91 14 ! 10.8 0.0 0.00043 0.73 1 37 [. 913 952 .. 913 961 .. 0.81 15 ! 17.0 0.0 4.7e-06 0.008 6 47 .. 956 992 .. 947 995 .. 0.83 16 ! 15.3 0.1 1.7e-05 0.029 18 56 .] 998 1037 .. 990 1037 .. 0.93 17 ! 16.9 0.0 5.2e-06 0.0089 1 44 [. 1049 1091 .. 1049 1105 .. 0.84 18 ? 6.4 0.0 0.01 18 18 55 .. 1100 1137 .. 1095 1138 .. 0.91 19 ! 15.7 0.0 1.2e-05 0.021 1 48 [. 1117 1163 .. 1117 1164 .. 0.88 20 ? 5.9 0.0 0.015 25 7 37 .. 1155 1185 .. 1152 1193 .. 0.90 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 2.4e-06 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeeg.ltpl 53 Lle g ++++ +++eg+ L +A+++g++e++++Lla ++++ + + g +tpl FUN_001562-T1 161 LLEEG-WSVHEPTDEGESLLSLACSAGYFELAQVLLAMNASVDDRGSKGdCTPL 213 89999.******************************999999999999988887 PP == domain 2 score: 22.1 bits; conditional E-value: 1.2e-07 Ank_5 14 gegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 ++ tpL+ A+++g+ +iv+lLl++ +d+n + g+t+l +A FUN_001562-T1 209 DC--TPLMEASSGGYIDIVKLLLDHTADVNSQSQAGNTALIYA 249 34..**************************************9 PP == domain 3 score: 21.4 bits; conditional E-value: 2e-07 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangv 40 Ll +g ++ + ++g+ tpL+ Aa++g+ +++++Ll++g+ FUN_001562-T1 261 LLSHGaDIEAHNENGH--TPLMEAASGGHVNVAKMLLERGA 299 899**99999999999..*******************9887 PP == domain 4 score: 20.4 bits; conditional E-value: 4.1e-07 Ank_5 11 rldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 +++++++ +L +A+++g+le+v++Ll+ g+d k++e t+l FUN_001562-T1 304 HSNEFKESALTLACYKGHLEMVKFLLDAGADQEHKTDEMHTAL 346 5789999*******************99999888888888876 PP == domain 5 score: 13.3 bits; conditional E-value: 7.1e-05 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 t+L+ A+ g+ e++rlLl++g+ +n+ ++ ++pl lA FUN_001562-T1 344 TALMEASMDGHVEVARLLLDHGAQVNMPADSFESPLTLA 382 99***************************999***9998 PP == domain 6 score: 31.0 bits; conditional E-value: 1.9e-10 Ank_5 13 dgegytpLhvAakygaleivrlLlangvdlnlkdeeg.ltpldlA 56 ++egytpL+ A++ g+l++v lLl++g+d+++++ee +t+l lA FUN_001562-T1 405 NDEGYTPLMEASREGHLDMVALLLEHGADIHAQTEETqETALSLA 449 67899*************************************998 PP == domain 7 score: 31.1 bits; conditional E-value: 1.8e-10 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 Ll++g ++ ++++ tpL+ Aa g+ ++v++Ll++g+++n++++ g+tpl +A FUN_001562-T1 461 LLQAGaSI-----EQGSSTPLMEAAQEGHVDLVKFLLERGANVNATTATGDTPLSFA 512 56666333.....45556************************************887 PP == domain 8 score: 10.6 bits; conditional E-value: 0.00051 Ank_5 18 tpLhvAakygaleivrlLlangvd 41 tpL +A+++g+ +++ +Ll g+d FUN_001562-T1 507 TPLSFACENGHTDVADVLLSAGAD 530 9******************65555 PP == domain 9 score: 12.1 bits; conditional E-value: 0.00017 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkde 47 Ll +g adl ++ + g tp ++Aa++g+l v++L+ +g+++n ++ FUN_001562-T1 524 LLSAG-ADLEHESEAGRTPVMKAARAGHLCTVQFLISRGASVNHQTT 569 78999.99999999999*******************99999987665 PP == domain 10 score: 17.8 bits; conditional E-value: 2.7e-06 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangvdl 42 L+ +g +++++++ ++ t+L +A+ +g+l +v+lLla+g+d+ FUN_001562-T1 557 LISRGaSVNHQTTMNDH-TVLSLACAGGHLAVVELLLAHGADP 598 78899999999887777.***********************97 PP == domain 11 score: 9.3 bits; conditional E-value: 0.0013 Ank_5 16 gytpLhvAakygaleivrlLlangvd 41 ++L+ Aak+g++ ++++Ll+n+ FUN_001562-T1 605 NSNILIEAAKGGHAAVICFLLENPIV 630 349******************99865 PP == domain 12 score: 16.9 bits; conditional E-value: 5.4e-06 Ank_5 13 dgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 d ++ t+L +A+ +g+ e+v lLl g+d+ +d+ g+tpl lA FUN_001562-T1 858 DSNSDTALTLASAGGHDELVTLLLVKGADIEHRDKKGCTPLILA 901 44444*************************************98 PP == domain 13 score: 30.8 bits; conditional E-value: 2.2e-10 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeeg.ltpldlA 56 Ll g ad+ ++d++g tpL++Aa +g++ v++Ll++g+d+ ++ ++ +t+l lA FUN_001562-T1 880 LLVKG-ADIEHRDKKGCTPLILAATAGHASTVEILLDHGADIEAQSDRTkDTALSLA 935 56667.77778888888*************************************998 PP == domain 14 score: 10.8 bits; conditional E-value: 0.00043 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLl...a 37 Ll++g ++ ++ +++ t+L +A+++g+ e+v+lL+ a FUN_001562-T1 913 LLDHGaDIEAQSDRTKD-TALSLACSGGRQEVVELLIskeA 952 89999888887777777.******************96644 PP == domain 15 score: 17.0 bits; conditional E-value: 4.7e-06 Ank_5 6 padlnrldgegytpLhvAakygaleivrlLlangvdlnlkde 47 ++++ + ytpL +Aa++g+ i++lLl +++ +n ++ FUN_001562-T1 956 HRNVSD-----YTPLSLAASGGYVGIIQLLLRHRAEINSRTG 992 444444.....5**************************9875 PP == domain 16 score: 15.3 bits; conditional E-value: 1.7e-05 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeeg.ltpldlA 56 pL++A+ +g++ v+lLl+ g+d+n++ e + +t+l lA FUN_001562-T1 998 SPLMLASMNGHSAAVKLLLDMGSDINAQIETNkNTALTLA 1037 79***********************************998 PP == domain 17 score: 16.9 bits; conditional E-value: 5.2e-06 Ank_5 1 Lleng.padlnrldgegytpLhvAakygaleivrlLlangvdlnl 44 L+e++ ++ + +++ g tpL+ Aa++g+ e+ r+Ll+ g+d+n+ FUN_001562-T1 1049 LVERRaNIEHRAKT--GLTPLMEAASGGYVEVGRILLDKGGDVNA 1091 78898555555555..55***********************9996 PP == domain 18 score: 6.4 bits; conditional E-value: 0.01 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpldl 55 t+L +Aa +g++ + lLl +g+ + +k++ g++pl l FUN_001562-T1 1100 TALTIAADKGHYKFCDLLLSRGAVVDVKNKKGNSPLWL 1137 99*********************************955 PP == domain 19 score: 15.7 bits; conditional E-value: 1.2e-05 Ank_5 1 LlengpadlnrldgegytpLhvAakygaleivrlLlangvdlnlkdee 48 Ll +g a ++ ++++g+ pL +Aa++g+le+ +lL+ +g+d+ +d++ FUN_001562-T1 1117 LLSRG-AVVDVKNKKGNSPLWLAANGGHLEVCQLLFSYGADVDSQDNR 1163 56677.5566799*****************************999985 PP == domain 20 score: 5.9 bits; conditional E-value: 0.015 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLla 37 ad++++d++++ +L+ A ++g+ ++++L++ FUN_001562-T1 1155 ADVDSQDNRKVSVLMAAFRKGHIKVIKWLVK 1185 899**************************94 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.0 3.1e-09 5.3e-06 19 109 .. 143 233 .. 138 243 .. 0.81 2 ! 18.0 0.1 1.5e-06 0.0026 46 109 .. 242 299 .. 234 311 .. 0.79 3 ! 13.1 0.1 4.8e-05 0.082 46 107 .. 309 364 .. 299 368 .. 0.74 4 ! 15.9 0.1 6.6e-06 0.011 40 113 .. 368 437 .. 366 450 .. 0.80 5 ! 12.9 0.1 5.7e-05 0.096 17 70 .. 441 496 .. 433 507 .. 0.62 6 ! 18.4 0.1 1.2e-06 0.002 19 107 .. 473 560 .. 469 565 .. 0.90 7 ! 10.7 0.1 0.00026 0.44 39 70 .. 565 596 .. 562 599 .. 0.90 8 ! 10.7 0.1 0.00027 0.46 45 88 .. 604 648 .. 598 651 .. 0.80 9 ! 19.6 0.1 4.8e-07 0.00082 37 108 .. 850 917 .. 844 930 .. 0.77 10 ! 15.7 0.0 7.4e-06 0.013 46 109 .. 928 985 .. 918 996 .. 0.80 11 ! 13.4 0.1 4e-05 0.068 49 110 .. 999 1055 .. 987 1066 .. 0.79 12 ! 15.4 0.0 9.6e-06 0.016 18 119 .. 1030 1132 .. 1024 1134 .. 0.79 13 ! 24.9 0.0 1.1e-08 1.9e-05 20 146 .. 1100 1225 .. 1097 1228 .. 0.78 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 3.1e-09 Ank_KRIT1 19 deeLrkaaakGdeetvariLn....vrekvddpes.lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqee 109 +++L +a+ +Gd+++v ++L+ v+e +d+ es l A+ +G e q+Lla+ d +++ tPl+ a + ++++kllld++ FUN_001562-T1 143 ARSLAEACLEGDVSAVRKLLEegwsVHEPTDEGESlLSLACSAGYFELAQVLLAMNASVDD-----RGSKGDCTPLMEASSGGYIDIVKLLLDHTA 233 56899***************8333355666677776678****************766555.....5688899***988877***********964 PP == domain 2 score: 18.0 bits; conditional E-value: 1.5e-06 Ank_KRIT1 46 dpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqee 109 + +l++A+ gG e+v+ +Ll G d ++ +++ tPl+ a ++++v k+ll++ FUN_001562-T1 242 GNTALIYACCGGYEDVVAVLLSHGA---D---IEAHNENGHTPLMEAASGGHVNVAKMLLERGA 299 5678******************994...5...778899999**9755555**********9854 PP == domain 3 score: 13.1 bits; conditional E-value: 4.8e-05 Ank_KRIT1 46 dpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 + +l+ A+ Gh e++++Ll+ G + + + e+ t l+ a ++++v +llld+ FUN_001562-T1 309 KESALTLACYKGHLEMVKFLLDAGADQE------HKTDEMHTALMEASMDGHVEVARLLLDH 364 4567888999999999999998885333......4567888888888888899999999887 PP == domain 4 score: 15.9 bits; conditional E-value: 6.6e-06 Ank_KRIT1 40 vrekvddpes.lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqee.fdpt 113 v+ +d es l+ Aa gGh e +lL++ G + +++++ e tPl+ a ++l+++ lll++ + ++ FUN_001562-T1 368 VNMPADSFESpLTLAACGGHVELADLLIKRGAF------LEEVNDEGYTPLMEASREGHLDMVALLLEHGAdIHAQ 437 6667777787799******************98......556889999*******************985314444 PP == domain 5 score: 12.9 bits; conditional E-value: 5.7e-05 Ank_KRIT1 17 lddeeLrkaaakGdeetvariLnvrekvddpes..lvaAakgGheevlqlLlalGk 70 ++++ L a++ G ++++a +L+ ++++ s l+ Aa+ Gh + +++Ll+ G FUN_001562-T1 441 TQETALSLACCGGFQDVAAFLLQAGASIEQGSStpLMEAAQEGHVDLVKFLLERGA 496 33444555555555556666777777776665566777777777777777777663 PP == domain 6 score: 18.4 bits; conditional E-value: 1.2e-06 Ank_KRIT1 19 deeLrkaaakGdeetvariLnvrekvddpes.....lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldq 107 ++ L +aa++G +++v+ +L+ +v+ + + l A+ Gh++v ++Ll G d +++ ++ tP++ a ++l +++l+++ FUN_001562-T1 473 STPLMEAAQEGHVDLVKFLLERGANVNATTAtgdtpLSFACENGHTDVADVLLSAGA---D---LEHESEAGRTPVMKAARAGHLCTVQFLISR 560 57899*********************9999899999*****************9994...5...778889999999999999999999999875 PP == domain 7 score: 10.7 bits; conditional E-value: 0.00026 Ank_KRIT1 39 nvrekvddpeslvaAakgGheevlqlLlalGk 70 n +++++d l A+ gGh v++lLla G FUN_001562-T1 565 NHQTTMNDHTVLSLACAGGHLAVVELLLAHGA 596 6678999**********************994 PP == domain 8 score: 10.7 bits; conditional E-value: 0.00027 Ank_KRIT1 45 ddpeslvaAakgGheevlqlLlalGk.adpdPepvkslkpeystP 88 d+++ l+ AakgGh v+ +Ll+ a+p p++s+++ + tP FUN_001562-T1 604 DNSNILIEAAKGGHAAVICFLLENPIvANPPELPLNSMPSSLPTP 648 456679****************98751666667999999999998 PP == domain 9 score: 19.6 bits; conditional E-value: 4.8e-07 Ank_KRIT1 37 iLnvrekvddpes...lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPl.lAaiGrenlkvikllldqe 108 +++v +++ d++s l+ A+ gGh+e + lLl +G d +++ +++ tPl lAa ++++ +++lld+ FUN_001562-T1 850 MIDVDQQT-DSNSdtaLTLASAGGHDELVTLLLVKGA---D---IEHRDKKGCTPLiLAAT-AGHASTVEILLDHG 917 55666666.3333344*******************94...5...889999999**945555.5**********985 PP == domain 10 score: 15.7 bits; conditional E-value: 7.4e-06 Ank_KRIT1 46 dpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPl.lAaiGrenlkvikllldqee 109 + +l A+ gG++ev++lL+ + +a+ + + + tPl lAa G + + +i+lll ++ FUN_001562-T1 928 KDTALSLACSGGRQEVVELLISK-EANFE-----HRNVSDYTPLsLAASG-GYVGIIQLLLRHRA 985 456899**************986.45544.....6666778*********.**********9864 PP == domain 11 score: 13.4 bits; conditional E-value: 4e-05 Ank_KRIT1 49 slvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeef 110 l+ A+ Gh+ +++lLl++G+ d + +++++ +t l a +++ +v++ll++++ FUN_001562-T1 999 PLMLASMNGHSAAVKLLLDMGS-DIN----AQIETNKNTALTLACFQGRHEVVSLLVERRAN 1055 5899*****************6.333....23577899999888889**********98754 PP == domain 12 score: 15.4 bits; conditional E-value: 9.6e-06 Ank_KRIT1 18 ddeeLrkaaakGdeetvariLnvrekvddpes.....lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllld 106 +++ L+ a+ +G +e+v +++ r ++++ + l+ Aa gG ev ++Ll++G+ d + pv s +t l a +++ k lll+ FUN_001562-T1 1030 KNTALTLACFQGRHEVVSLLVERRANIEHRAKtgltpLMEAASGGYVEVGRILLDKGG-DVNALPVPSS---KDTALTIAADKGHYKFCDLLLS 1119 5677999999********9999999997665578888******************985.4444566554...567787777889*********9 PP Ank_KRIT1 107 qeefdptrrlkge 119 + + ++ kg+ FUN_001562-T1 1120 RGAVVDVKNKKGN 1132 9877666666665 PP == domain 13 score: 24.9 bits; conditional E-value: 1.1e-08 Ank_KRIT1 20 eeLrkaaakGdeetvariLnvrekvddpes.....lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqe 108 + L+ aa kG + +L vd ++ l Aa gGh ev qlL+ G ad d s+++ + l+Aa ++++kvik l+++ FUN_001562-T1 1100 TALTIAADKGHYKFCDLLLSRGAVVDVKNKkgnspLWLAANGGHLEVCQLLFSYG-ADVD-----SQDNRKVSVLMAAFRKGHIKVIKWLVKHV 1187 56777777777777776666554443222233446*******************9.4555.....6677777889******************9 PP Ank_KRIT1 109 efdptrrlkgetyleiarerkgenweeeeklLkeAydk 146 + p+ + i+ + ++++++ ++L +A ++ FUN_001562-T1 1188 HQFPSDSECTRFISTISDKELLNKCHKNMEILVTAKER 1225 88888888888889999999999999999999888776 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0038 6.5 33 88 .. 144 199 .. 136 206 .. 0.84 2 ! 8.0 0.0 0.002 3.5 38 88 .. 216 266 .. 211 272 .. 0.80 3 ! 13.1 0.1 5.5e-05 0.093 26 92 .. 270 337 .. 266 340 .. 0.84 4 ! 9.8 0.0 0.00056 0.96 31 88 .. 342 399 .. 336 407 .. 0.80 5 ! 13.1 0.1 5.3e-05 0.091 33 115 .. 410 494 .. 401 505 .. 0.81 6 ! 10.8 0.0 0.00028 0.48 35 89 .. 509 563 .. 505 571 .. 0.90 7 ! 10.2 0.1 0.00043 0.74 32 86 .. 573 627 .. 566 631 .. 0.91 8 ! 7.0 0.1 0.0042 7.2 38 86 .. 901 950 .. 853 952 .. 0.54 9 ! 8.1 0.0 0.0019 3.3 38 90 .. 901 954 .. 896 985 .. 0.68 10 ! 8.1 0.1 0.0019 3.2 36 97 .. 1001 1064 .. 991 1090 .. 0.78 11 ! 6.3 0.0 0.0071 12 33 115 .. 1100 1186 .. 1095 1189 .. 0.79 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0038 ANK_LRRK2 33 klLekaCeegdvvmaEcllllgadvnkktkt.esliyqvCErgsplelvelllssgv 88 + L +aC egdv + ll+ g v + t++ esl+ C g el+++ll++ + FUN_001562-T1 144 RSLAEACLEGDVSAVRKLLEEGWSVHEPTDEgESLLSLACSAGY-FELAQVLLAMNA 199 56899********************9977643999999999877.999999998765 PP == domain 2 score: 8.0 bits; conditional E-value: 0.002 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkktk..tesliyqvCErgsplelvelllssgv 88 a + g + ++ ll advn +++ +++liy C g+ ++v +lls+g+ FUN_001562-T1 216 ASSGGYIDIVKLLLDHTADVNSQSQagNTALIYACC--GGYEDVVAVLLSHGA 266 5566667889999********876522799******..677799******997 PP == domain 3 score: 13.1 bits; conditional E-value: 5.5e-05 ANK_LRRK2 26 ldsdlkeklLekaCeegdvvmaEcllllgadvnkktk..tesliyqvCErgsplelvelllssgvrEqd 92 ++++ ++ L +a + g+v +a ll+ ga +n +++ +es + C +g+ le+v+ ll+ g+ ++ FUN_001562-T1 270 AHNENGHTPLMEAASGGHVNVAKMLLERGACINSHSNefKESALTLACYKGH-LEMVKFLLDAGADQEH 337 5666667778899999*****************988744699********98.9********9987654 PP == domain 4 score: 9.8 bits; conditional E-value: 0.00056 ANK_LRRK2 31 keklLekaCeegdvvmaEcllllgadvnkktk..tesliyqvCErgsplelvelllssgv 88 ++ L +a ++g+v +a ll ga+vn ++ +++l C g+++el++ll+++g+ FUN_001562-T1 342 MHTALMEASMDGHVEVARLLLDHGAQVNMPADsfESPLTLAAC--GGHVELADLLIKRGA 399 45667889********************877622567888888..8999********997 PP == domain 5 score: 13.1 bits; conditional E-value: 5.3e-05 ANK_LRRK2 33 klLekaCeegdvvmaEcllllgadvnkktkt..esliyqvCErgsplelvelllssgvr.EqdlrkaLavsvkrgdgevvsllLkk 115 + L +a eg++ m+ ll+ gad+ +t++ e+ + C g+ ++++ ll+ g+ Eq + L+ + ++g ++v lL++ FUN_001562-T1 410 TPLMEASREGHLDMVALLLEHGADIHAQTEEtqETALSLACC-GGFQDVAAFLLQAGASiEQGSSTPLMEAAQEGHVDLVKFLLER 494 5588999******************98776411334444443.67789999999999755999*********************98 PP == domain 6 score: 10.8 bits; conditional E-value: 0.00028 ANK_LRRK2 35 LekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvr 89 L+ aCe+g++ +a+ ll gad+++++++ ++ r+++l v+ l+s+g+ FUN_001562-T1 509 LSFACENGHTDVADVLLSAGADLEHESEAGRTPVMKAARAGHLCTVQFLISRGAS 563 6679***********************999999999999999********99986 PP == domain 7 score: 10.2 bits; conditional E-value: 0.00043 ANK_LRRK2 32 eklLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllss 86 +++L+ aC+ g+++++E ll gad +k k++s i +g++++++ ll++ FUN_001562-T1 573 HTVLSLACAGGHLAVVELLLAHGADPLHKLKDNSNILIEAAKGGHAAVICFLLEN 627 678999****************************999999999999999999875 PP == domain 8 score: 7.0 bits; conditional E-value: 0.0042 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkktk..tesliyqvCErgsplelvelllss 86 a + g++ +E ll gad++ +++ +++ + C g+ +e+vell+s+ FUN_001562-T1 901 AATAGHASTVEILLDHGADIEAQSDrtKDTALSLAC-SGGRQEVVELLISK 950 334445555666666666665443211222333333.34445666666554 PP == domain 9 score: 8.1 bits; conditional E-value: 0.0019 ANK_LRRK2 38 aCeegdvvmaEcllllgadvnkktk..tesliyqvCErgsplelvelllssgvrE 90 a + g++ +E ll gad++ +++ +++ + C g+ +e+vell+s+ ++ FUN_001562-T1 901 AATAGHASTVEILLDHGADIEAQSDrtKDTALSLAC-SGGRQEVVELLISKEANF 954 5566788899**********9876411344455556.57779*******987653 PP == domain 10 score: 8.1 bits; conditional E-value: 0.0019 ANK_LRRK2 36 ekaCeegdvvmaEcllllgadvnkk..tktesliyqvCErgsplelvelllssgvr.EqdlrkaL 97 a ++g+++ + ll +g+d+n + t++++ + C +g e+v ll+++ ++ E ++ L FUN_001562-T1 1001 MLASMNGHSAAVKLLLDMGSDINAQieTNKNTALTLACFQGR-HEVVSLLVERRANiEHRAKTGL 1064 5577899999999**********86336778899999*9998.899****998765255555555 PP == domain 11 score: 6.3 bits; conditional E-value: 0.0071 ANK_LRRK2 33 klLekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgv..rEqdlrk..aLavsvkrgdgevvsllLkk 115 + L+ a ++g+ + ll ga v+ k+k+ g++le+ +ll+s g+ qd rk L+++ ++g +v+ l+k+ FUN_001562-T1 1100 TALTIAADKGHYKFCDLLLSRGAVVDVKNKKGNSPLWLAANGGHLEVCQLLFSYGAdvDSQDNRKvsVLMAAFRKGHIKVIKWLVKH 1186 56777888889999999999999888777766655667789999*********986226789887336999**********999875 PP >> KH_1 KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.3 1.8 3.9e-19 6.6e-16 2 64 .. 1438 1501 .. 1437 1502 .. 0.92 Alignments for each domain: == domain 1 score: 58.3 bits; conditional E-value: 3.9e-19 KH_1 2 erilvPaskvgriIGkgGstIkeIreetgakIkipsedde.sderivtIsGtpeavekAkelie 64 ++ v +s ++r+IG+gG++I+ Ire+tga+I+i ++++ ++++ivtI+G+p+a ++A +li+ FUN_001562-T1 1438 KKMAVSSSVISRVIGRGGCNINAIRETTGAHIDIDTNRQKaTGSCIVTIKGPPDATRQAHQLIQ 1501 5799*****************************88555567**********************8 PP >> SAM_1 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 0.0 6.6e-11 1.1e-07 6 62 .. 1968 2023 .. 1964 2024 .. 0.94 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 6.6e-11 SAM_1 6 edVgeWLesiglgqYadsFrkgyidgetLlqlteddLeklgvtllgHrkkIlsaiqr 62 +++++Le + l+ + F++++id+++Ll+++e+d+ ++g + g+r k+l++ ++ FUN_001562-T1 1968 DTLQTFLERLSLSSHLGLFQENEIDLDALLLMSEKDYADIGLPK-GPRVKLLNSTRQ 2023 57899*************************************99.********9886 PP >> KH_Vigilin Vigilin KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.9 3.2e+03 27 54 .. 914 943 .. 910 945 .. 0.72 2 ? -3.3 0.0 6.9 1.2e+04 27 45 .. 1020 1036 .. 1008 1046 .. 0.67 3 ! 16.8 0.1 3.7e-06 0.0062 22 62 .. 1458 1501 .. 1453 1507 .. 0.84 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.9 KH_Vigilin 27 keTgtnIEist..skdqsltflitGkpeaV 54 ++g+ IE+ + kd+ l++ +G +++V FUN_001562-T1 914 LDHGADIEAQSdrTKDTALSLACSGGRQEV 943 578999998872246666999999988888 PP == domain 2 score: -3.3 bits; conditional E-value: 6.9 KH_Vigilin 27 keTgtnIEistskdqsltf 45 ++ +++I t+k++ lt+ FUN_001562-T1 1020 SDINAQI--ETNKNTALTL 1036 5556666..5788888886 PP == domain 3 score: 16.8 bits; conditional E-value: 3.7e-06 KH_Vigilin 22 ckdImkeTgtnIEistskdq...sltflitGkpeaVekAkreil 62 ++ I + Tg++I+i t++++ s +++i+G p+a ++A++ i FUN_001562-T1 1458 INAIRETTGAHIDIDTNRQKatgSCIVTIKGPPDATRQAHQLIQ 1501 689***********99987522258***************9875 PP >> KH-I_KHDC4-BBP KHDC4/BBP-like, KH-domain type I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.1 7.2e-06 0.012 7 33 .. 1446 1472 .. 1443 1505 .. 0.84 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 7.2e-06 KH-I_KHDC4-BBP 7 vvgriiGprgsnlkhIenetgakvrlr 33 v++r+iG++g+n++ I+++tga + + FUN_001562-T1 1446 VISRVIGRGGCNINAIRETTGAHIDID 1472 899*********************996 PP >> KH_NusA_2nd NusA-like second KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.2 5.7e-06 0.0097 27 64 .. 1439 1476 .. 1430 1479 .. 0.89 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 5.7e-06 KH_NusA_2nd 27 evvVpdeqlSlAIGKrGqNvrLaakLtgwkidikseee 64 + +V+++ +S++IG+ G N+ + + tg +idi + + FUN_001562-T1 1439 KMAVSSSVISRVIGRGGCNINAIRETTGAHIDIDTNRQ 1476 67899****************************98765 PP >> SAM_2 SAM domain (Sterile alpha motif) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.1 5.5e-05 0.093 8 62 .. 1969 2021 .. 1968 2025 .. 0.89 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 5.5e-05 SAM_2 8 svaeWLrsigleqykdnFkdagitgaelllrlteedLkelGitsvghrkkilkki 62 +++ +L+++ l+++ F++++i+ ++ll ++e+d +++G g+r k+l++ FUN_001562-T1 1969 TLQTFLERLSLSSHLGLFQENEIDL-DALLLMSEKDYADIGL-PKGPRVKLLNST 2021 5788*********************.***************9.677788888875 PP >> KH_KhpA-B KhpA/KhpB, KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 0.00024 0.41 34 56 .. 1441 1463 .. 1435 1475 .. 0.86 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00024 KH_KhpA-B 34 kvagedlGkvIGkqGrtldAlrt 56 +v+++ + +vIG+ G +++A+r FUN_001562-T1 1441 AVSSSVISRVIGRGGCNINAIRE 1463 56777899*************95 PP >> ScdA_N Domain of Unknown function (DUF542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.58 1e+03 30 44 .. 142 156 .. 141 164 .. 0.78 2 ? 2.1 0.1 0.13 2.2e+02 27 46 .. 250 269 .. 247 271 .. 0.87 3 ? -3.0 0.0 5.1 8.8e+03 30 49 .. 275 294 .. 274 296 .. 0.86 4 ? 1.1 0.0 0.25 4.3e+02 28 49 .. 384 405 .. 384 407 .. 0.86 5 ? -2.2 0.0 2.7 4.6e+03 30 49 .. 408 427 .. 406 429 .. 0.88 6 ? 0.2 0.1 0.5 8.6e+02 27 44 .. 450 467 .. 450 470 .. 0.80 7 ? -2.3 0.0 2.9 5e+03 32 49 .. 474 491 .. 471 493 .. 0.84 8 ? 1.2 0.0 0.25 4.3e+02 33 53 .. 735 755 .. 733 757 .. 0.87 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.58 ScdA_N 30 GkvsLaeAakekgld 44 G +sLaeA+ e ++ FUN_001562-T1 142 GARSLAEACLEGDVS 156 99*******998664 PP == domain 2 score: 2.1 bits; conditional E-value: 0.13 ScdA_N 27 CCgGkvsLaeAakekgldle 46 CCgG++ + +++ g d+e FUN_001562-T1 250 CCGGYEDVVAVLLSHGADIE 269 ******99999988888876 PP == domain 3 score: -3.0 bits; conditional E-value: 5.1 ScdA_N 30 GkvsLaeAakekgldleevl 49 G+ +L eAa +++++ l FUN_001562-T1 275 GHTPLMEAASGGHVNVAKML 294 999******99999998876 PP == domain 4 score: 1.1 bits; conditional E-value: 0.25 ScdA_N 28 CgGkvsLaeAakekgldleevl 49 CgG+v+La+ + ++g leev FUN_001562-T1 384 CGGHVELADLLIKRGAFLEEVN 405 *********9999998888875 PP == domain 5 score: -2.2 bits; conditional E-value: 2.7 ScdA_N 30 GkvsLaeAakekgldleevl 49 G+ +L eA +e ld+ ++l FUN_001562-T1 408 GYTPLMEASREGHLDMVALL 427 999************98876 PP == domain 6 score: 0.2 bits; conditional E-value: 0.5 ScdA_N 27 CCgGkvsLaeAakekgld 44 CCgG + +a+ + ++g FUN_001562-T1 450 CCGGFQDVAAFLLQAGAS 467 ****99999888777765 PP == domain 7 score: -2.3 bits; conditional E-value: 2.9 ScdA_N 32 vsLaeAakekgldleevl 49 +L eAa+e +dl ++l FUN_001562-T1 474 TPLMEAAQEGHVDLVKFL 491 6899*********98776 PP == domain 8 score: 1.2 bits; conditional E-value: 0.25 ScdA_N 33 sLaeAakekgldleevlaeLe 53 +La+A+k+++l le + eL FUN_001562-T1 735 KLAKALKKANLSLESIPPELL 755 79************9988886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2321 (0.0908593); expected 510.9 (0.02) Passed bias filter: 826 (0.0323351); expected 510.9 (0.02) Passed Vit filter: 125 (0.00489333); expected 25.5 (0.001) Passed Fwd filter: 23 (0.000900372); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.78u 0.44s 00:00:01.22 Elapsed: 00:00:00.45 # Mc/sec: 18714.04 // Query: FUN_001563-T1 [L=101] Description: FUN_001563 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 888 (0.0347622); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1039.86 // Query: FUN_001564-T1 [L=351] Description: FUN_001564 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-22 79.2 18.7 3.1e-14 53.1 0.3 3.0 4 Ion_trans_2 Ion channel 0.0052 16.5 1.1 0.0052 16.5 1.1 2.9 3 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.046 14.8 1.3 0.068 14.2 0.1 1.9 2 CKI Colicin-K immunity 3.3 8.8 5.4 0.64 11.1 0.6 2.2 3 Sm_multidrug_ex Putative small multi-drug export protein Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 1.6 1e+04 5 16 .. 14 25 .. 8 38 .. 0.57 2 ! 53.1 0.3 4.8e-18 3.1e-14 5 75 .. 61 132 .. 57 136 .. 0.86 3 ! 35.6 5.4 1.3e-12 8.6e-09 7 47 .. 175 211 .. 162 215 .. 0.72 4 ? -2.9 0.1 1.4 9.3e+03 59 69 .. 252 262 .. 241 274 .. 0.50 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 1.6 Ion_trans_2 5 lvlifgtviyll 16 ++lifg+v+ +l FUN_001564-T1 14 AFLIFGAVVPWL 25 444555554444 PP == domain 2 score: 53.1 bits; conditional E-value: 4.8e-18 Ion_trans_2 5 lvlifgtviyll.eegwegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllflavlge 75 +++f+t + + +e +w ++ al f + +tTvGYG+i+Prt++g+l++iv+ l+Gipl+ll+++ +g+ FUN_001564-T1 61 EFITFSTSAHDVlSEADPRWGYFVALEFLLQAVTTVGYGNITPRTPVGQLLCIVVSLFGIPLTLLLIKSIGD 132 55667777777775555588***********************************************99987 PP == domain 3 score: 35.6 bits; conditional E-value: 1.3e-12 Ion_trans_2 7 lifgtviylleegwegwsfldalyfsvvtltTvGYGdivPr 47 ++ g ++ + e+w+f++++yf ++t+tT+G+Gd+vP+ FUN_001564-T1 175 MTQGCILMY----LERWTFVEGIYFWFITYTTIGFGDYVPT 211 233333333....5788***********************8 PP == domain 4 score: -2.9 bits; conditional E-value: 1.4 Ion_trans_2 59 iliGiplfllf 69 l+ +++++ + FUN_001564-T1 252 FLFDLCVVASV 262 23333334444 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 1.1 8.2e-07 0.0052 128 233 .. 2 132 .. 1 140 [. 0.75 2 ? -1.1 2.3 0.19 1.2e+03 44 64 .. 164 190 .. 151 197 .. 0.65 3 ? 1.4 8.1 0.033 2.1e+02 170 242 .. 183 273 .. 161 274 .. 0.77 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 8.2e-07 Ion_trans 128 ksllnlllllllvlfifaiigvqlfggklkk..........................eekewenpdngrtnFdn..............fgnallwl 183 ++l+++ l+ +l ++if+ ++ lf + ++++ +F++ ++ al +l FUN_001564-T1 2 GTLCKTYLIRVLAFLIFGAVVPWLF-----VlvedsrentieakyqvleslhvsmisK---YNMTIEEFITFSTsahdvlseadprwgYFVALEFL 89 6788888888888888888888888.....2334677778888888888887765531...223334455666677777777777888******** PP Ion_trans 184 fqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviid 233 +q tt+g+g+i++ t ++ ++++++ l+g+ l+ lli i d FUN_001564-T1 90 LQAVTTVGYGNITPRTPVGQ-------LLCIVVSLFGIPLTLLLIKSIGD 132 ********************.......88888888888877777766665 PP == domain 2 score: -1.1 bits; conditional E-value: 0.19 Ion_trans 44 viftlemllkiialgl......kkkYl 64 vi ++ ml++++++g+ +++++ FUN_001564-T1 164 VILFFIMLFRMMTQGCilmyleRWTFV 190 566666889999999944444444444 PP == domain 3 score: 1.4 bits; conditional E-value: 0.033 Ion_trans 170 rtnFdnfgnallwlfqtlttegwgdilyatldek.................gsaiaviyfvlfiilggvlllnll.iaviidnfqeltera 242 + + +f++ +++ f+t tt+g+gd +++ + g+ ++ + ++ ++ +++l+ l+ +a ++++++ +te++ FUN_001564-T1 183 YLERWTFVEGIYFWFITYTTIGFGDYVPTEYHLDsrnvdirqfflnetvneGNELNPGIIITEVVYTSIFLFDLCvVASVVNSIAAATEEW 273 444447999****************999999888889999999999999998888888888888888888888852688888888888765 PP >> CKI Colicin-K immunity # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 1.1e-05 0.068 12 60 .. 19 68 .. 6 100 .. 0.80 2 ? -2.5 0.1 1.7 1.1e+04 23 32 .. 172 181 .. 157 212 .. 0.52 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.1e-05 CKI 12 eslipwllilllndkdntfl.liifiasihvllypyskltisryikettk 60 +++pwl++l+ + ++nt+ + + s+hv + ++ti ++i +t FUN_001564-T1 19 GAVVPWLFVLVEDSRENTIEaKYQVLESLHVSMISKYNMTIEEFITFSTS 68 5789***********99986157889*********99********87775 PP == domain 2 score: -2.5 bits; conditional E-value: 1.7 CKI 23 lndkdntfll 32 + ++ +l FUN_001564-T1 172 FRMMTQGCIL 181 3333333322 PP >> Sm_multidrug_ex Putative small multi-drug export protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.1 0.82 5.2e+03 17 37 .. 10 30 .. 1 65 [. 0.51 2 ? 11.1 0.6 0.0001 0.64 21 83 .. 110 171 .. 94 204 .. 0.81 3 ? -2.3 0.0 1.4 9.2e+03 24 52 .. 252 277 .. 240 299 .. 0.50 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.82 Sm_multidrug_ex 17 lealllsvlgnllpvpllllf 37 + +l++ ++g ++p +++l+ FUN_001564-T1 10 IRVLAFLIFGAVVPWLFVLVE 30 444555555555555554443 PP == domain 2 score: 11.1 bits; conditional E-value: 0.0001 Sm_multidrug_ex 21 llsvlgnllpvpllllflekllellkkvkllkkflekleekaekksekve.kygflGLalFvai 83 ll+++++l +pl+ll+++++ + ++vk+++k++ k+e+k ++ + + + + + +++F+++ FUN_001564-T1 110 LLCIVVSLFGIPLTLLLIKSIGD--SNVKIINKIVVKFERKFLHRPQPENlQTKSAVILFFIML 171 79*******************99..78999***********99977766668888888899887 PP == domain 3 score: -2.3 bits; conditional E-value: 1.4 Sm_multidrug_ex 24 vlgnllpvpllllflekllellkkvkllk 52 +l++l++v ++ + + ++++k ++ FUN_001564-T1 252 FLFDLCVVASVVNS---IAAATEEWKKAD 277 44444444444433...222222333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (351 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 752 (0.0294382); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 3607.92 // Query: FUN_001565-T1 [L=223] Description: FUN_001565 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-18 65.2 15.2 2.7e-11 43.7 0.5 2.7 3 Ion_trans_2 Ion channel 1.2e-05 25.1 4.1 0.0062 16.2 1.5 2.3 2 Ion_trans Ion transport protein Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.7 0.5 2.1e-15 2.7e-11 22 75 .. 29 83 .. 7 87 .. 0.84 2 ! 27.3 6.1 2.7e-10 3.4e-06 12 47 .. 125 162 .. 113 179 .. 0.75 3 ? -1.5 0.0 0.27 3.4e+03 17 35 .. 188 206 .. 171 209 .. 0.71 Alignments for each domain: == domain 1 score: 43.7 bits; conditional E-value: 2.1e-15 Ion_trans_2 22 gwsfldalyfsvvtltTv.GYGdivPrtdagrlftivyiliGiplfllflavlge 75 w++ + f++ +tTv GYG+i+Prt+ag+l++iv+ l+Gipl+l++l+ +ge FUN_001565-T1 29 FWTYKASASFVLQAVTTVaGYGNITPRTPAGQLVCIVVSLFGIPLTLAILKSVGE 83 46****************9*******************************99986 PP == domain 2 score: 27.3 bits; conditional E-value: 2.7e-10 Ion_trans_2 12 viyll..eegwegwsfldalyfsvvtltTvGYGdivPr 47 +i + ++ gw+f++++yf +vt tT+G+Gd+ P FUN_001565-T1 125 IITNGliGMTVGGWTFVEGIYFGFVTSTTIGFGDYMPS 162 33322554446788*********************996 PP == domain 3 score: -1.5 bits; conditional E-value: 0.27 Ion_trans_2 17 eegwegwsfldalyfsvvt 35 +++w+ +++ ++ f +v FUN_001565-T1 188 TTFWHPADIVRGIIFLFVL 206 4567777888877777764 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.0 6.3e-05 0.81 173 226 .. 29 77 .. 11 81 .. 0.75 2 ! 16.2 1.5 4.8e-07 0.0062 140 204 .. 114 173 .. 110 209 .. 0.74 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 6.3e-05 Ion_trans 173 Fdnfgnallwlfqtltte.gwgdilyatldekgsaiaviyfvlfiilggvlllnl 226 F ++ + +++q tt+ g+g+i++ t ++ ++ +++ ++g+ l+l++ FUN_001565-T1 29 FWTYKASASFVLQAVTTVaGYGNITPRTPAGQ------LVCIVVSLFGIPLTLAI 77 5567777778889888888*************......77777777776666665 PP == domain 2 score: 16.2 bits; conditional E-value: 4.8e-07 Ion_trans 140 vlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwlfqtlttegwgdilyatldek.....g 204 v++if ++++q+ + ++ +g ++ f++ +++ f+t+tt+g+gd ++ +l++ FUN_001565-T1 114 VVVIFVLMSMQII-------TNGLIGMTVGGWT---FVEGIYFGFVTSTTIGFGDYMPSPLRSVktniqQ 173 7899999999999.......4455566666665...9***********************9998555550 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (223 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 590 (0.0230965); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2192.64 // Query: FUN_001567-T1 [L=338] Description: FUN_001567 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-21 76.2 8.1 2.9e-13 50.0 1.3 3.6 4 Ion_trans_2 Ion channel ------ inclusion threshold ------ 0.17 12.5 0.1 0.35 11.5 0.1 1.4 1 DUF1128 Protein of unknown function (DUF1128) 5.4 7.2 4.9 2.6 8.2 0.8 2.4 3 FA_desaturase Fatty acid desaturase Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.2 0.75 6.4e+03 51 73 .. 10 32 .. 5 35 .. 0.56 2 ! 50.0 1.3 3.4e-17 2.9e-13 9 77 .. 65 134 .. 59 136 .. 0.88 3 ! 37.8 0.8 2.2e-13 1.9e-09 2 53 .. 170 217 .. 163 226 .. 0.82 4 ? 0.4 0.8 0.1 8.7e+02 54 77 .. 237 260 .. 233 268 .. 0.72 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 0.75 Ion_trans_2 51 grlftivyiliGiplfllflavl 73 r++++ + + +++++f+ ++ FUN_001567-T1 10 LRFIAFSLLISLSAWLFVFVEYT 32 56666555555555555555554 PP == domain 2 score: 50.0 bits; conditional E-value: 3.4e-17 Ion_trans_2 9 fgtviylleeg.wegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllflavlgevl 77 f+t++y ++ +w++ +a+ f++ +tT+GYG i+P+t++g++++i+ l+Gip+ l ++ +gev+ FUN_001567-T1 65 FSTTVYEAMSVpAPEWTYHNAIDFVLQAVTTIGYGSITPKTATGQVMCIFMCLVGIPISMLSIKSVGEVF 134 5666666645547799*************************************************99986 PP == domain 3 score: 37.8 bits; conditional E-value: 2.2e-13 Ion_trans_2 2 vlllvlifgtviylleegwegwsfldalyfsvvtltTvGYGdivPrtdagrl 53 ++l+v+ g ++++l +gws+l+++yf +vtltT+G+Gd+ r +a+r+ FUN_001567-T1 170 MILIVIGNGLIVVSL----KGWSLLEGVYFWFVTLTTIGFGDYLVREPAQRI 217 455555556666666....677************************999887 PP == domain 4 score: 0.4 bits; conditional E-value: 0.1 Ion_trans_2 54 ftivyiliGiplfllflavlgevl 77 fti+ ++ +++++l+l + +vl FUN_001567-T1 237 FTIIMSFFSLTYLVLCLCLVSSVL 260 677777777777777777666654 PP >> DUF1128 Protein of unknown function (DUF1128) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 4.1e-05 0.35 36 62 .. 39 65 .. 35 69 .. 0.92 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 4.1e-05 DUF1128 36 ekyedlkelYemVmkkssfSvsEmqai 62 eky+ l+ lYe k ++S++E + + FUN_001567-T1 39 EKYQSLRSLYEAMAWKYNMSINEFNNF 65 89*********************9987 PP >> FA_desaturase Fatty acid desaturase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 0.37 3.1e+03 133 172 .. 76 119 .. 31 127 .. 0.59 2 ? 8.2 0.8 0.00031 2.6 103 173 .. 133 205 .. 122 226 .. 0.71 3 ? -1.8 0.0 0.35 3e+03 155 186 .. 243 272 .. 232 291 .. 0.57 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.37 FA_desaturase 133 r...wrllaalllllawlglwlallllagllll.lwllpllvll 172 + w++ a+ ++l ++ +++ + + ++ + +++++ FUN_001567-T1 76 PapeWTYHNAIDFVLQAVTTIGYGSITPKTATGqVMCIFMCLVG 119 03348888888888876666665555555555565555555554 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00031 FA_desaturase 103 lllawllalllllwarrlarrkrpiksrrrrwrllaalllllaw.lglwlallllagllll....lwllpllvllf 173 +++ w++a + ++ l+r + ++ + + + +l+ +++l++++ ++++ l g+ ll +w++ l +++f FUN_001567-T1 133 VFALWFMAIIQKFEKKVLKRPEPRSLETKSAVILFSLMILIVIGnGLIVVSL---KGWSLLegvyFWFVTLTTIGF 205 3444999999888888888888888888877666666666664433333333...444444456999999999987 PP == domain 3 score: -1.8 bits; conditional E-value: 0.35 FA_desaturase 155 llagllll.lwllpllvllfllalvf.nyleHyg 186 +++ l + +l+l++++++l v + +H++ FUN_001567-T1 243 FFS----LtYLVLCLCLVSSVLNSVVaALENHNF 272 222....236667766666666665534445555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (338 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1516 (0.0593463); expected 510.9 (0.02) Passed bias filter: 793 (0.0310433); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3302.25 // Query: FUN_001568-T1 [L=98] Description: FUN_001568 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (98 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 649 (0.0254061); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.37s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 1019.81 // Query: FUN_001569-T1 [L=228] Description: FUN_001569 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-14 54.3 19.1 3.2e-07 30.6 5.6 3.4 4 Ion_trans_2 Ion channel ------ inclusion threshold ------ 0.065 13.5 1.4 0.065 13.5 1.4 2.1 2 PMP1_2 ATPase proteolipid family 0.38 12.2 0.0 0.38 12.2 0.0 2.2 3 DUF4834 Domain of unknown function (DUF4834) Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.6 5e-10 4.2e-06 40 77 .. 2 39 .. 1 41 [. 0.95 2 ? 2.1 0.4 0.03 2.6e+02 16 40 .. 50 83 .. 38 84 .. 0.66 3 ! 30.6 5.6 3.8e-11 3.2e-07 6 47 .. 72 115 .. 66 119 .. 0.77 4 ! 5.3 0.4 0.0029 25 54 78 .. 151 175 .. 143 176 .. 0.89 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 5e-10 Ion_trans_2 40 GYGdivPrtdagrlftivyiliGiplfllflavlgevl 77 GYG i+P+t+ g+ + +++ liGipl+ ++++ +ge++ FUN_001569-T1 2 GYGYITPQTPEGKTLFMIICLIGIPLTMIAFKSVGELI 39 *********************************99876 PP == domain 2 score: 2.1 bits; conditional E-value: 0.03 Ion_trans_2 16 l........eeg.wegwsfldalyfsvvtltTvG 40 + e++ ++g s + + f+v+ l+T G FUN_001569-T1 50 FeekilkrsEHThVQGKSAVLLFVFMVTLLFTCG 83 2344445555555777788999999999999998 PP == domain 3 score: 30.6 bits; conditional E-value: 3.8e-11 Ion_trans_2 6 vlifgtviyll..eegwegwsfldalyfsvvtltTvGYGdivPr 47 +++ t+++++ e+ e +++l++ y+ +vtltT+G+Gd+vP FUN_001569-T1 72 FVFMVTLLFTCgcLETLEHLTWLEGTYMWFVTLTTIGFGDYVPL 115 33444444444676778999***********************7 PP == domain 4 score: 5.3 bits; conditional E-value: 0.0029 Ion_trans_2 54 ftivyiliGiplfllflavlgevlt 78 ++ ++++iG+++++++l+ ++ v++ FUN_001569-T1 151 VVLFLVIIGFSIVAAVLNAIAAVFE 175 57899***************99986 PP >> PMP1_2 ATPase proteolipid family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.6 0.87 7.4e+03 20 27 .. 38 45 .. 18 49 .. 0.59 2 ? 13.5 1.4 7.6e-06 0.065 10 39 .. 151 185 .. 145 187 .. 0.82 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 0.87 PMP1_2 20 ACvAivlt 27 + +v t FUN_001569-T1 38 LILILVNT 45 33344445 PP == domain 2 score: 13.5 bits; conditional E-value: 7.6e-06 PMP1_2 10 viLvFvLvGLACvAivltilY.....RkWqeRqRG 39 v+L v++G vA vl + RkWq R RG FUN_001569-T1 151 VVLFLVIIGFSIVAAVLNAIAavfeeRKWQVRCRG 185 89999********9998766333455********9 PP >> DUF4834 Domain of unknown function (DUF4834) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 2.7 3 2.6e+04 12 23 .. 20 31 .. 15 66 .. 0.57 2 ? -3.6 0.2 3 2.6e+04 4 15 .. 70 78 .. 68 89 .. 0.49 3 ? 12.2 0.0 4.4e-05 0.38 7 62 .. 148 211 .. 146 226 .. 0.69 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 3 DUF4834 12 iallvigLsils 23 i l+ i+L +++ FUN_001569-T1 20 ICLIGIPLTMIA 31 333333333332 PP == domain 2 score: -3.6 bits; conditional E-value: 3 DUF4834 4 Llfilliiiall 15 Llf++ ++ l FUN_001569-T1 70 LLFVF---MVTL 78 33332...2222 PP == domain 3 score: 12.2 bits; conditional E-value: 4.4e-05 DUF4834 7 illiiiallvigLsilsvvlravfglgrrkkss........kkkqkqqaksynsaqqkttarsq 62 i ++++l++ig+si+++vl+a+ ++ +++k + +k k++++++n +++k+++ ++ FUN_001569-T1 148 IESVVLFLVIIGFSIVAAVLNAIAAVFEERKWQvrcrgcipRKIHKRGENRQNDPSEKSDNGNN 211 5667999***************966555444445566667777777777777777666664433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (228 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1082 (0.0423566); expected 510.9 (0.02) Passed bias filter: 643 (0.0251713); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 2276.57 // Query: FUN_001570-T1 [L=216] Description: FUN_001570 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-11 43.8 14.5 7.7e-11 42.2 3.4 3.0 3 Ion_trans_2 Ion channel 0.0016 18.2 4.4 0.0028 17.4 4.4 1.4 1 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.032 15.1 0.4 0.032 15.1 0.4 1.8 2 DUF3267 Putative zincin peptidase 0.056 12.9 0.1 0.14 11.6 0.0 1.5 2 30K_MP_C_Ter C-Terminal of 30K viral movement proteins 0.091 12.1 3.2 0.05 12.9 0.5 1.7 1 DUF2206 Predicted membrane protein (DUF2206) 0.74 10.9 3.7 0.46 11.6 1.1 2.0 3 Sm_multidrug_ex Putative small multi-drug export protein Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.3 0.0014 6 55 77 .. 2 24 .. 1 26 [. 0.91 2 ! 42.2 3.4 1.8e-14 7.7e-11 2 52 .. 60 105 .. 56 108 .. 0.74 3 ? 1.2 0.2 0.11 4.8e+02 53 77 .. 137 161 .. 124 163 .. 0.65 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0014 Ion_trans_2 55 tivyiliGiplfllflavlgevl 77 +i++ l+Gip+++l+++ +ge++ FUN_001570-T1 2 CILVSLLGIPITVLAFKSIGELI 24 89*****************9987 PP == domain 2 score: 42.2 bits; conditional E-value: 1.8e-14 Ion_trans_2 2 vlllvlifgtviylleegwegwsfldalyfsvvtltTvGYGdivPrtdagr 52 +l+lv + g+++ l ++w+f++++yf +vtltT+G+Gd++P+t r FUN_001570-T1 60 TLVLVTANGFIMMDL----FQWTFIESVYFWFVTLTTIGFGDFAPVTSQ-R 105 233333344444444....678************************987.5 PP == domain 3 score: 1.2 bits; conditional E-value: 0.11 Ion_trans_2 53 lftivyiliGiplfllflavlgevl 77 lf +y ++ +++++ +l+ +++++ FUN_001570-T1 137 LFYSFYLTFCLCMVSSILNSIVSAI 161 4556666666666666666666655 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 4.4 6.5e-07 0.0028 128 235 .. 51 161 .. 48 167 .. 0.79 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 6.5e-07 Ion_trans 128 ksllnlllllllvlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnallwlfqtlttegwgdilyatldek.................... 203 ks++ l+ll+l+++ + + i++ lf ++ +f++++++ f+tltt+g+gd ++t ++ FUN_001570-T1 51 KSVALLTLLTLVLVTANGFIMMDLF-----------------QW---TFIESVYFWFVTLTTIGFGDFAPVTSQRIeklsinvskrhqkekgmatl 126 5677888999999999999999999.................34...59*************************99******************** PP Ion_trans 204 ...gsaiaviyfvlfiilggvlllnlliaviidnf 235 +s + +f +f++ + + +++ ++ i++++ FUN_001570-T1 127 vdhTSNLFTGLFYSFYLTFCLCMVSSILNSIVSAI 161 99955555555555555555555555555555555 PP >> DUF3267 Putative zincin peptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.4 7.6e-06 0.032 39 92 .. 45 99 .. 9 103 .. 0.88 2 ? -2.0 0.4 1.6 6.7e+03 55 67 .. 140 152 .. 123 161 .. 0.49 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 7.6e-06 DUF3267 39 esilskkrfiiillaPfviisilllllllllp.spalylllllaintagsvgDll 92 + ++kk+ + +l+ +v++++ +++++ l++ +++ ++++++ t + +gD+ FUN_001570-T1 45 PKRMRKKSVALLTLLTLVLVTANGFIMMDLFQwTFIESVYFWFVTLTTIGFGDFA 99 445699**************************99999****************96 PP == domain 2 score: -2.0 bits; conditional E-value: 1.6 DUF3267 55 fviisilllllll 67 + ++++l++++ FUN_001570-T1 140 SFYLTFCLCMVSS 152 2233333333333 PP >> 30K_MP_C_Ter C-Terminal of 30K viral movement proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 3.3e-05 0.14 7 46 .. 16 55 .. 12 60 .. 0.92 2 ? -2.0 0.0 0.49 2.1e+03 96 127 .. 103 131 .. 82 140 .. 0.63 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 3.3e-05 30K_MP_C_Ter 7 vfksiGekvikelnskkedykkkllerkkelrreGkkvki 46 fksiGe +++ +n+ e++ k l+r+ +r + k v + FUN_001570-T1 16 AFKSIGELIARCVNNIVENFEMKILKREEPKRMRKKSVAL 55 59********************************999975 PP == domain 2 score: -2.0 bits; conditional E-value: 0.49 30K_MP_C_Ter 96 dsvaigpsvrlekirfrnsdgvklltmldtGs 127 +++ s+++ k++ + ++ t++d s FUN_001570-T1 103 SQRIEKLSINVSKRH---QKEKGMATLVDHTS 131 444444445555433...34456777777666 PP >> DUF2206 Predicted membrane protein (DUF2206) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.5 1.2e-05 0.05 74 139 .. 16 82 .. 4 96 .. 0.82 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 1.2e-05 DUF2206 74 afksivslfskilsslveeflnpeatqelavivkkeatllhlilkylyllaqffiviGila.llvkk 139 afksi +l+ + ++++ve+f + ++e ++k++ l ++l+++ ++a fi++ +++ +++ + FUN_001570-T1 16 AFKSIGELIARCVNNIVENFEMKILKREEPKRMRKKSVALLTLLTLVLVTANGFIMMDLFQwTFIES 82 8*******************88855555555566666666688899999*********999888765 PP >> Sm_multidrug_ex Putative small multi-drug export protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.1 0.00011 0.46 22 83 .. 1 64 [. 1 95 [. 0.68 2 ? -1.0 0.2 0.85 3.6e+03 31 64 .. 73 108 .. 56 138 .. 0.51 3 ? -1.5 0.0 1.2 5.1e+03 15 32 .. 140 157 .. 130 165 .. 0.71 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00011 Sm_multidrug_ex 22 lsvlgnllpvpllllflekllellkkvkllkkflekleekaekksekve.k...ygflGLalFvai 83 +++l++ll +p+++l ++++ el+++ +++++e +e k k++e + + + +l L+ +v + FUN_001570-T1 1 MCILVSLLGIPITVLAFKSIGELIARC--VNNIVENFEMKILKREEPKRmRkksVALLTLLTLVLV 64 699*******************87774..7777777777777766555434011444444444443 PP == domain 2 score: -1.0 bits; conditional E-value: 0.85 Sm_multidrug_ex 31 vpllllflekllellkkvkl..lkkflekleekaek 64 ++ + f+e++ ++ + + + f ++ ek FUN_001570-T1 73 DLFQWTFIESVYFWFVTLTTigFGDFAPVTSQRIEK 108 334444444444433332222444555444444444 PP == domain 3 score: -1.5 bits; conditional E-value: 1.2 Sm_multidrug_ex 15 dplealllsvlgnllpvp 32 + +++++l+++ ++l+ + FUN_001570-T1 140 SFYLTFCLCMVSSILNSI 157 567778888887776544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (216 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 973 (0.0380896); expected 510.9 (0.02) Passed bias filter: 610 (0.0238794); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2185.31 // Query: FUN_001571-T1 [L=317] Description: FUN_001571 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-22 80.2 13.6 2.7e-13 50.1 0.0 3.2 4 Ion_trans_2 Ion channel 0.0025 17.5 13.8 0.017 14.8 2.3 2.5 2 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.14 13.3 0.9 0.47 11.6 0.4 2.2 2 Sm_multidrug_ex Putative small multi-drug export protein 0.15 13.4 0.1 2.9 9.3 0.0 2.3 2 EF-hand_11 EF-hand domain 0.21 11.4 0.0 0.33 10.7 0.0 1.2 1 DUF6925 Family of unknown function (DUF6925) Domain annotation for each model (and alignments): >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.2 2.3 1.2e+04 5 11 .. 18 24 .. 9 34 .. 0.50 2 ! 50.1 0.0 5.2e-17 2.7e-13 11 78 .. 68 135 .. 59 136 .. 0.90 3 ! 36.6 2.4 8.5e-13 4.3e-09 16 50 .. 176 214 .. 162 223 .. 0.70 4 ? -0.1 0.1 0.24 1.2e+03 55 73 .. 243 261 .. 232 271 .. 0.48 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 2.3 Ion_trans_2 5 lvlifgt 11 ++ ++++ FUN_001571-T1 18 MWCLSSW 24 2222222 PP == domain 2 score: 50.1 bits; conditional E-value: 5.2e-17 Ion_trans_2 11 tviylleegwegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllflavlgevlt 78 +++ +l+e ++ws+ a+ f++ ltT+GYG i+P+t+ g+l++i+++l Gip++ l+++ +ge++ FUN_001571-T1 68 MAYEALSEPKRQWSYNVAMRFVFQALTTIGYGFITPQTPQGQLLCILVALPGIPITMLAFQAIGEMIA 135 5555667778899***************************************************9985 PP == domain 3 score: 36.6 bits; conditional E-value: 8.5e-13 Ion_trans_2 16 l.....eegwegwsfldalyfsvvtltTvGYGdivPrtda 50 + ++ +w+f++a+yf +vtltT+G+Gd++ + FUN_001571-T1 176 VngsvmMDP-YEWTFVEAVYFWFVTLTTIGFGDYTMVRSQ 214 123433444.499*********************988555 PP == domain 4 score: -0.1 bits; conditional E-value: 0.24 Ion_trans_2 55 tivyiliGiplfllflavl 73 t ++ l+ ++l+l++++ + FUN_001571-T1 243 TGLFFLFDMILCLCIVSSV 261 4333333333333333322 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 2.3 3.3e-06 0.017 135 217 .. 13 116 .. 5 139 .. 0.79 2 ! 7.7 3.9 0.00048 2.5 175 231 .. 188 269 .. 161 274 .. 0.79 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 3.3e-06 Ion_trans 135 lllllvlfifaiigvqlfggklkk...................eekewenpdngrtnFdn..............fgnallwlfqtlttegwgdily 197 l +++++++ ++++v + + ++ + ++++++nF+n + a+ ++fq ltt+g+g i++ FUN_001571-T1 13 LGFFFMWCLSSWFFVLVE-----HteqsdvevkrkilqstfdsMASKYNMSIQDFNNFSNmayealsepkrqwsYNVAMRFVFQALTTIGYGFITP 103 557888888888888888.....334567999999999988642566666677899999999999999999999********************** PP Ion_trans 198 atldekgsaiaviyfvlfii 217 +t +++ ++++++ FUN_001571-T1 104 QTPQGQ-------LLCILVA 116 *****9.......4444433 PP == domain 2 score: 7.7 bits; conditional E-value: 0.00048 Ion_trans 175 nfgnallwlfqtlttegwgdilyatldek.........................gsaiaviyfvlfiilggvlllnlliavi 231 +f++a+++ f+tltt+g+gd + + ++ + + +++ +++++++ +ln ++ +i FUN_001571-T1 188 TFVEAVYFWFVTLTTIGFGDYTMVRSQRImelsinisqnhddgkdeaekktfeiFTGLFFLFDMILCLCIVSSVLNSVVSFI 269 699*****************66666555589999999999999999988887777777777777777777777777776665 PP >> Sm_multidrug_ex Putative small multi-drug export protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.4 9.2e-05 0.47 20 83 .. 109 169 .. 92 204 .. 0.81 2 ? -1.9 0.0 1.4 7.1e+03 24 49 .. 247 273 .. 239 293 .. 0.56 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 9.2e-05 Sm_multidrug_ex 20 lllsvlgnllpvpllllflekllellkkvkllkkflekleekaekksekvekygflGLalFvai 83 ll++l+ l +p+++l ++ + e+++++ +++++ek+e+k +k++e +++ +L+++v + FUN_001571-T1 109 QLLCILVALPGIPITMLAFQAIGEMIARW--VNNIVEKFERKIMKREEPR-GMQTKSLVFLVSL 169 58999*******************88876..9999999999999977654.5666666666654 PP == domain 2 score: -1.9 bits; conditional E-value: 1.4 Sm_multidrug_ex 24 vlgnllpvplll.lflekllellkkvk 49 +l++++ + ++ +l+++++++++ k FUN_001571-T1 247 FLFDMILCLCIVsSVLNSVVSFIEENK 273 445533333333255666665555544 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.00056 2.9 4 38 .. 40 74 .. 37 94 .. 0.88 2 ? 1.7 0.0 0.13 6.8e+02 37 68 .. 269 300 .. 261 316 .. 0.80 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00056 EF-hand_11 4 drdilarlqkavashyhaivqefenfdtlksntvs 38 +r il ++as+y +q+f+nf + +++s FUN_001571-T1 40 KRKILQSTFDSMASKYNMSIQDFNNFSNMAYEALS 74 6899999999******************9988877 PP == domain 2 score: 1.7 bits; conditional E-value: 0.13 EF-hand_11 37 vsreefraictrrvqiltdeqfdrlwselpvn 68 + ++fra c v t++q d +++ n FUN_001571-T1 269 IEENKFRAPCPGCVSRRTQDQVDNEINNISSN 300 66789******************999988777 PP >> DUF6925 Family of unknown function (DUF6925) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 6.4e-05 0.33 28 83 .. 31 86 .. 19 89 .. 0.87 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 6.4e-05 DUF6925 28 FardagepvaveakderlslvTarGairlepladlrpvAyetlssdgerWshavaL 83 +++ + v+++ ++++ ++++ +++++ +++ +Aye+ls+ +++Ws +va+ FUN_001571-T1 31 HTEQSDVEVKRKILQSTFDSMASKYNMSIQDFNNFSNMAYEALSEPKRQWSYNVAM 86 55666667777778899999999999****************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1399 (0.0547661); expected 510.9 (0.02) Passed bias filter: 807 (0.0315913); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3102.34 // Query: FUN_001572-T1 [L=61] Description: FUN_001572 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 10.5 0.0 0.23 10.5 0.0 1.0 1 Metallopep Putative peptidase family Domain annotation for each model (and alignments): >> Metallopep Putative peptidase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 9.1e-06 0.23 66 116 .. 6 56 .. 1 60 [. 0.85 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 9.1e-06 Metallopep 66 genkltveetneaasseltlsykpleqnppvhlvllvakdseltfdapeak 116 g+ + ++++e+++++++ ++p +++p l++ ++++ +++a+e+ FUN_001572-T1 6 GNMDFHENTDSENDTEVIESLFTPYTDEPIASLCIRLCRNRISDYAATEYD 56 555566668999*****************************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (61 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 470 (0.0183989); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.35s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 624.19 // Query: FUN_001573-T1 [L=1271] Description: FUN_001573 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-73 246.2 0.0 8.1e-73 245.6 0.0 1.3 1 LSDAT_euk SLOG in TRPM 3.7e-55 188.3 0.0 8.7e-55 187.1 0.0 1.7 2 TRPM2 TRPM2-like domain 6.8e-20 71.7 0.2 1.9e-19 70.2 0.2 1.7 1 LSDAT_prok SLOG in TRPM, prokaryote 3e-13 50.0 20.5 5.4e-13 49.2 19.6 1.9 2 Ion_trans Ion transport protein 0.0014 19.2 1.6 0.0037 17.9 1.6 1.7 1 TRPM_tetra Tetramerisation domain of TRPM ------ inclusion threshold ------ 0.05 14.4 0.0 0.13 13.1 0.0 1.6 1 DUF1363 Protein of unknown function (DUF1363) Domain annotation for each model (and alignments): >> LSDAT_euk SLOG in TRPM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 245.6 0.0 1.9e-76 8.1e-73 1 256 [. 218 492 .. 218 505 .. 0.86 Alignments for each domain: == domain 1 score: 245.6 bits; conditional E-value: 1.9e-76 LSDAT_euk 1 akyvrlsvdtkpedilkllekewklelPkLvisvhGgaenFelqpklkrvlrkGllkaaett..gAWiiteGintGvvrhvgdalkelssq..... 89 aky+rls dtkpe l+l+ ++wkl++P +v+s+hGg++nF+l+p+ k+++++Gl+kaa+tt gAWiit+G+n G+++ vg+a++e +s+ FUN_001573-T1 218 AKYIRLSDDTKPELTLDLMVRQWKLKKPDIVVSIHGGLKNFQLDPRHKEIFNRGLIKAAKTTnsGAWIITGGVNLGIMKAVGHAVQEGQSMhwggt 313 89***********************************************************95569*******************99866335666 PP LSDAT_euk 90 ..skrkivtiGiapwGviknredli....gkdv.vveyqtls.npksklavlnsrHslFllvDdGtvgkyGa.eiklRrklEkaiseqkiaarkk. 175 ++++i iGia+wG ++++e+li gk + +y++++ ++ k ++ln H++FllvDdGt+g+ Ga e+++R++lEk+i+ + ++++++ FUN_001573-T1 314 ssRHHRIRCIGIATWGYVERNENLInpveGKGYyPASYRVEHsFQRGKPVSLNPDHTHFLLVDDGTQGQCGAkEVQFRAQLEKVIACKPNIQKQEf 409 55899999*****************5555455445667666647788999*********************648************9987776652 PP LSDAT_euk 176 .kkvpvvcvvleGGpstiktvleyvrespkvPvvvvdgsGraaDllafahkl...leedgklksevkeellsliqkvfelekkea 256 +vpvv+vvleGG+ ++k+v e+v++ +P vvv+g+ raaD+lafah++ ++ +++++++ ++ l+++i+++f + ++ FUN_001573-T1 410 gFGVPVVTVVLEGGADALKAVKESVMH--GIPAVVVEGTRRAADILAFAHNNcefVSGSRRVSKDRRSPLITKIKESFPKYAGNE 492 268************************..*********************861115677889999999**********5433332 PP >> TRPM2 TRPM2-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 187.1 0.0 2e-58 8.7e-55 1 257 [] 581 840 .. 581 840 .. 0.86 2 ? -4.0 0.2 4.2 1.8e+04 86 95 .. 1240 1249 .. 1207 1268 .. 0.38 Alignments for each domain: == domain 1 score: 187.1 bits; conditional E-value: 2e-58 TRPM2 1 eiFtediqwkssdLeeamtdALvnnkpeFVrLllenGvnlkefltkerLeeLYnslseksllrkllkkvkeeekskskklkkkaelslsevskvlr 96 +iFt d +w s L+++m+dAL +++FV+L+l +Gv++++flt +rL++LYns ++ l++ll v+ + +s ++++ +l+ FUN_001573-T1 581 KIFTPDTDWPSGSLDDVMLDALRLGRVDFVKLFLAHGVSMRDFLTVSRLTKLYNSADPGNHLYSLLSSVACIP---------SGPYSFRDINLLLE 667 69*****************************************************************986522.........23477889****** PP TRPM2 97 ellgdvtqplypkkkkrdkklskkkke......k....sslllklakkesekeaeleedpvrdLflWAvlqnrkelAeifWeqakdsvaaALaask 182 el+g +++ply k+++r+++ + + + s + + +++++ ++ a++ e+p+r+LflWAvl +r elA ++W++++++++ ALaa++ FUN_001573-T1 668 ELIGAHCEPLYFKDTSRTNESGASLSAvdnvdgEggivSVEFEPKTEDDISEFATRFEKPFRELFLWAVLLSRFELALFIWQKGEEAITDALAACR 763 ***********99888877765443321111111111112223444455556667779************************************** PP TRPM2 183 ilkelakeesd..aeeaeemkelaakyeklaigvfsecyrkdeeraqkLLvrkselWgkttcLqLAleAdaksFvah 257 + + + + d e ++++k++a ++e+laigv++ecy++de ++ L r + Wg++ L+LA +A+ak+F+ah FUN_001573-T1 764 LFQVMHDKIGDgyYEMRNALKQHAVEFENLAIGVLDECYNEDEVLSEMLVERDLSKWGGMCALKLAAAAKAKRFLAH 840 ******997774478899**********************************************************9 PP == domain 2 score: -4.0 bits; conditional E-value: 4.2 TRPM2 86 lslsevskvl 95 + + v++++ FUN_001573-T1 1240 KTSERVEQLV 1249 1111111111 PP >> LSDAT_prok SLOG in TRPM, prokaryote # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.2 0.2 4.6e-23 1.9e-19 3 167 .. 248 457 .. 246 475 .. 0.83 Alignments for each domain: == domain 1 score: 70.2 bits; conditional E-value: 4.6e-23 LSDAT_prok 3 vlvlvGgasgldeeeaarllkllrevlapaae..algavvidgGtdaGvmrllgraraa...........learfPLiGVApegtValpa.esak. 83 v+++ Gg ++++ + r ++++ ++l +aa+ + ga +i+gG++ G+m+++g+a ++ + r iG+A g V+ ++ +++ FUN_001573-T1 248 VVSIHGGLKNFQLDP--RHKEIFNRGLIKAAKttNSGAWIITGGVNLGIMKAVGHAVQEgqsmhwggtssRHHRIRCIGIATWGYVERNEnLINPv 341 899999999998887..999*******9998622569******************987622222222111455667***********998555559 PP LSDAT_prok 84 ................ek.daaeLephHthlvLvpg....srWGdEspwlarvaeaia.....ekr.......psvtllvnGgeitraditeslaa 146 ++ ++++L+p+Hth++Lv+ + E+++ a++ + ia + + p vt+++ Gg+++ ++++es+ + FUN_001573-T1 342 egkgyypasyrvehsfQRgKPVSLNPDHTHFLLVDDgtqgQCGAKEVQFRAQLEKVIAckpniQ-KqefgfgvPVVTVVLEGGADALKAVKESVMH 436 9*************996669**************97444244457*************866642.26899999*********************** PP LSDAT_prok 147 grpilvlaGsgrladeiaaal 167 g p +v++G+ r+ad +a a+ FUN_001573-T1 437 GIPAVVVEGTRRAADILAFAH 457 ***************998666 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 0.66 2.8e+03 130 150 .. 861 881 .. 847 894 .. 0.82 2 ! 49.2 19.6 1.3e-16 5.4e-13 2 240 .. 905 1150 .. 904 1153 .. 0.79 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.66 Ion_trans 130 llnlllllllvlfifaiigvq 150 ++++l+ll+ l+if i+++ FUN_001573-T1 861 YWKVVLVLLCPLMIFKIFFYD 881 578999999999999998875 PP == domain 2 score: 49.2 bits; conditional E-value: 1.3e-16 Ion_trans 2 kifelfilllillntvvlaletyfqpeekelklleildlvftviftlemllkiialgl.....kkk.YlrspwnilDfvvvlpslislil.... 85 k+++ + + l +l + ++++ ++f++ ++ ei+ l+++++++++ + ++i k + Y+++ n++D ++ ++ l++++l FUN_001573-T1 905 KFWSHLGMHLFFLGLYTFVILFSFRKPPRP-SIYEIILLCWIGVIIVDEIRQVILEETnsvrrKLElYFQTSVNVIDACANVIALVGFVLrffe 997 567777777777777777777777774455.9***********************887788653337**********************97543 PP Ion_trans 86 sesk.eslsllrvlrll.rllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekewenpdngrtn.Fdnf 176 + + e+ ++l + ++ lrl+r+ ++ l + +++r+l ++++ + lll++++ ++++ + lf +n+ ++++ +++ FUN_001573-T1 998 V--TwEAARVLYCINFViFSLRLFRMYFVSGYLGPKIIMIKRMLADVFMWMCLLLICVCSYGVFRQALF----------FANK-EPYWGvINDV 1078 0..344566666666666889999999999999999999******************************..........3344.3344435577 PP Ion_trans 177 gnallwlfqtlttegwgdilyatldek.............gsaiaviyfvlfiilggvlllnlliaviidnfqelte 240 ++ +w + +e + + +++ ++k +++i+ ++++ ++++ +vll+nllia+ ++ f+e++ FUN_001573-T1 1079 FYKPYWHVY---GELFIE--QQAEEGKlatgeiplhdgghLKWIHRVLMAAYLLFTNVLLINLLIAIFSNVFNEVEV 1150 777777776...332222..33333335567788999999*********************************9875 PP >> TRPM_tetra Tetramerisation domain of TRPM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 1.6 8.7e-07 0.0037 1 24 [. 1235 1258 .. 1235 1266 .. 0.88 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 8.7e-07 TRPM_tetra 1 eeRIkvttErvEnmsqkveevnek 24 eeRI+ t+ErvE ++ kvee +e FUN_001573-T1 1235 EERIRKTSERVEQLVKKVEELHES 1258 79*******************995 PP >> DUF1363 Protein of unknown function (DUF1363) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 3e-05 0.13 70 107 .. 815 852 .. 790 859 .. 0.87 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3e-05 DUF1363 70 rrceyifgicsikgnsaarrkkflktplcqrylnnclk 107 r g+c++k +aa+ k+fl p cq ln k FUN_001573-T1 815 RDLSKWGGMCALKLAAAAKAKRFLAHPCCQSSLNSLWK 852 55556679***********************9998665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1271 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1615 (0.0632218); expected 510.9 (0.02) Passed bias filter: 1016 (0.0397729); expected 510.9 (0.02) Passed Vit filter: 115 (0.00450186); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.55u 0.40s 00:00:00.95 Elapsed: 00:00:00.44 # Mc/sec: 11744.75 // Query: FUN_001574-T1 [L=223] Description: FUN_001574 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (223 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 293 (0.01147); expected 510.9 (0.02) Passed bias filter: 277 (0.0108436); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2208.48 // Query: FUN_001576-T1 [L=136] Description: FUN_001576 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 13.1 0.0 0.18 12.5 0.0 1.2 1 DUF6955 Family of unknown function (DUF6955) Domain annotation for each model (and alignments): >> DUF6955 Family of unknown function (DUF6955) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 7.1e-06 0.18 6 52 .. 59 106 .. 57 114 .. 0.95 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 7.1e-06 DUF6955 6 lldeerleklkeagLaekikeafgG.lkvlevevteeqkkkilkeFpt 52 ll+ee ++l++++L ++++ + + +l++e+++e + i k F++ FUN_001576-T1 59 LLNEESEDELENSNLYHLVEGPAACpMALLNIETQRESCDWIYKSFKR 106 69******************999999********************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (136 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 433 (0.0169505); expected 510.9 (0.02) Passed bias filter: 335 (0.0131141); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.35s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1397.60 // Query: FUN_001577-T1 [L=758] Description: FUN_001577 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-53 180.9 0.7 1.6e-52 178.8 0.1 2.4 3 RabGAP-TBC Rab-GTPase-TBC domain 8.8e-31 107.7 2.4 1.6e-30 106.9 2.4 1.4 1 RabGap-TBC_2 RabGAP TBC domain Domain annotation for each model (and alignments): >> RabGAP-TBC Rab-GTPase-TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 0.14 1.8e+03 47 77 .. 12 43 .. 3 51 .. 0.80 2 ? -3.6 0.0 0.78 1e+04 149 165 .. 246 262 .. 244 266 .. 0.78 3 ! 178.8 0.1 1.2e-56 1.6e-52 2 216 .] 467 699 .. 466 699 .. 0.94 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.14 RabGAP-TBC 47 eeqIekDvprtfp.hsfsfkngegqesLrriL 77 e++++D+++t h++ ++++ +++L + L FUN_001577-T1 12 SEKVDEDLSNTEEnHEEVNTSHSHESRLTNTL 43 68999******995558888889999999887 PP == domain 2 score: -3.6 bits; conditional E-value: 0.78 RabGAP-TBC 149 lpklykhlkelgidlel 165 p+lyk + +l++d ++ FUN_001577-T1 246 SPELYKQFSKLSVDESV 262 599*****999997664 PP == domain 3 score: 178.8 bits; conditional E-value: 1.2e-56 RabGAP-TBC 2 elRgkvWklllgaek...................evkklkkeekkqeksskeeselekkeeseeeeqIekDvprtfphs..fsfkngegqesLrri 76 ++RgkvW+l +g++ ++ +kk+ +kq+ + s+ + ++ ++e I Dv+rtfp s +++ g+ ++ L++i FUN_001577-T1 467 SVRGKVWQLAIGNDLhithelfdifqshayeklfTTRLNKKNPAKQSIAELPTSDHSVVSKAHTVELIVMDVSRTFP-SlcIFQEGGPFHDVLHSI 561 68***********99****************998788888888888888888888888888888*************.557888888********* PP RabGAP-TBC 77 LkaysiynpdvgYcqGmnfivapllllyldeeeaFwcfvsLlekyklrdlytsdfpglkkalkvfeellkkklpklykhlkelgidlelfalkWfl 172 L ay y+pdvgY+qGm+f++a+ll l+++ ++aF cf++Ll+k + +++ d p + ++ fe l++ p+ly+h+ ++++++++++++W FUN_001577-T1 562 LGAYTCYRPDVGYVQGMSFLAAVLL-LNMEPSDAFICFANLLNKPCQLAFFRIDHPMMIAYFAAFEMFLEEEVPALYQHFIQENFTPDMYLIDWTF 656 *************************.999******************************************************************* PP RabGAP-TBC 173 tlflrefplslvlriwDvlll.egekvvllrvalailkllkeell 216 tlf++++pl++++r+wD +++ ge ++l+r+al +lk+++e ll FUN_001577-T1 657 TLFSKSLPLDTACRVWD-VFCrDGE-AFLFRAALGVLKFYQENLL 699 *****************.8884666.66*************9986 PP >> RabGap-TBC_2 RabGAP TBC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.9 2.4 1.2e-34 1.6e-30 2 158 .. 556 711 .. 555 741 .. 0.96 Alignments for each domain: == domain 1 score: 106.9 bits; conditional E-value: 1.2e-34 RabGap-TBC_2 2 eslfkvlkaysLyDtevgYaqgllfiaaplllympeeeaFsllvkLlkkydlrelfipdmpglelrLyqferlledllpalaihLqrqgvkssmya 97 + l ++l ay+ y ++vgY+qg++f+aa lll+m+ +aF + +Ll+k +f d p + fe +le+ +pal+ h+ +++ ++ my+ FUN_001577-T1 556 DVLHSILGAYTCYRPDVGYVQGMSFLAAVLLLNMEPSDAFICFANLLNKPCQLAFFRIDHPMMIAYFAAFEMFLEEEVPALYQHFIQENFTPDMYL 651 56899*********************************************999********9998888**************************** PP RabGap-TBC_2 98 sqwfltlFaykfpldlvlRifDlviaeGleailrlaiallkkneekllkllkldqllkfLk 158 +w tlF++++pld++ R++D+ + +G +++r a+ +lk +e+ll+ +++ +l +fL FUN_001577-T1 652 IDWTFTLFSKSLPLDTACRVWDVFCRDGEAFLFRAALGVLKFYQENLLE-MDFIHLGQFLS 711 *************************************************.99999999996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (758 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1682 (0.0658446); expected 510.9 (0.02) Passed bias filter: 630 (0.0246624); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7217.05 // Query: FUN_001578-T1 [L=1427] Description: FUN_001578 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1427 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1553 (0.0607947); expected 510.9 (0.02) Passed bias filter: 417 (0.0163241); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.51u 0.38s 00:00:00.89 Elapsed: 00:00:00.44 # Mc/sec: 13194.66 // Query: FUN_001578-T2 [L=1086] Description: FUN_001578 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 11.0 3.4 3 8.6 3.4 2.4 1 FlxA FlxA-like protein 9.1 7.3 11.3 1.1 10.2 4.6 2.9 2 CC4_CEP85 Centrosomal protein of 85 kDa-like, CC4 coiled-c 9.3 7.1 8.4 0.47 11.2 2.0 2.3 2 GreA_GreB_N Transcription elongation factor, N-terminal Domain annotation for each model (and alignments): >> FlxA FlxA-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 3.4 0.00036 3 21 61 .. 984 1027 .. 982 1072 .. 0.81 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00036 FlxA 21 sLrkqikkltkqlkelsdsdektkeekk....kqqqliqaQIqal 61 +L++qi+ +++ l+e +d + t kk + + iq+QIq+l FUN_001578-T2 984 NLHRQIAAMKNTLQEFQDLKR-TYYHKKkqrdQLFAWIQEQIQEL 1027 68999*999999999999833.3333331233666779*****98 PP >> CC4_CEP85 Centrosomal protein of 85 kDa-like, CC4 coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.5 0.51 4.4e+03 38 65 .. 96 123 .. 90 134 .. 0.71 2 ? 10.2 4.6 0.00013 1.1 6 85 .] 994 1082 .. 990 1082 .. 0.83 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.51 CC4_CEP85 38 qvaqEegtsqaLreEalekenalqqLre 65 + +Ee +sq r+ ++++ + qL++ FUN_001578-T2 96 KYKKEELASQHYRQHLMKTCFNSLQLQA 123 5568999999999999988666555543 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00013 CC4_CEP85 6 slkkeldrlkkviekqqkkmeql....ssqiqsL.....eeqvaqEegtsqaLreEalekenalqqLreavkELsvqnQdLieknltlq 85 ++ +e++ lk+ +++k+ +ql ++qiq+L + ++ q ++ +L eE+++ e+ + q r +v+E+ ++ +Li ++ lq FUN_001578-T2 994 NTLQEFQDLKRTYYHKKKQRDQLfawiQEQIQELgprheDGELLQPQECMSELTEEVRKMERRIAQARPLVEEIEAKIRELIRRSGILQ 1082 5567888999999999******977777788876444324589**************************************98876665 PP >> GreA_GreB_N Transcription elongation factor, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 2.0 5.5e-05 0.47 4 70 .. 995 1061 .. 992 1061 .. 0.92 2 ? -3.5 0.5 2.1 1.8e+04 54 62 .. 1066 1074 .. 1065 1077 .. 0.82 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 5.5e-05 GreA_GreB_N 4 TkegyeklkeeleelktverpeiaeaiaeA.reeGDlsENaeYdaAkeeqaelearIreLekkLarae 70 T + ++ lk+ + + k+ +r + + i+e+ +e G + E++e+ + +e +el +++r++e+++a+a+ FUN_001578-T2 995 TLQEFQDLKRTYYHKKK-QRDQLFAWIQEQiQELGPRHEDGELLQPQECMSELTEEVRKMERRIAQAR 1061 67889999999999999.**********972678*******************************996 PP == domain 2 score: -3.5 bits; conditional E-value: 2.1 GreA_GreB_N 54 elearIreL 62 e+ea+IreL FUN_001578-T2 1066 EIEAKIREL 1074 799****99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1086 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1427 (0.0558622); expected 510.9 (0.02) Passed bias filter: 413 (0.0161675); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.40u 0.39s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 10413.21 // Query: FUN_001579-T1 [L=337] Description: FUN_001579 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-55 187.2 0.3 4.3e-55 187.2 0.3 1.7 2 MIEAP Mitochondria-eating protein ------ inclusion threshold ------ 0.076 13.1 9.8 0.14 12.3 9.8 1.3 1 Phage_phiTE_211 Phage phiTE_211 family 0.077 13.8 0.9 0.16 12.8 0.9 1.5 1 Acyl-CoA_dh_2 Acyl-CoA dehydrogenase, C-terminal domain 0.11 13.4 10.7 0.44 11.4 10.7 2.1 1 Csm1_N Csm1 N-terminal domain 0.44 11.4 0.1 0.44 11.4 0.1 2.4 2 PANTS-like Synaptic plasticity regulator PANTS-like 1.1 10.0 15.4 1.1 9.9 13.5 2.0 2 OmpH Outer membrane protein (OmpH-like) 1.5 9.5 15.4 15 6.2 12.8 2.5 2 TMF_TATA_bd TATA element modulatory factor 1 TATA bindin 1.5 8.5 4.8 2.9 7.5 4.8 1.4 1 TMEM120A-B TMEM120A/B 2 9.4 12.7 4.1 8.4 12.7 1.6 1 SEEEED Serine-rich region of AP3B1, clathrin-adapto 6 7.4 7.9 8.9 6.8 5.3 2.4 2 DUF4446 Protein of unknown function (DUF4446) 6.3 7.3 10.1 3.4 8.2 6.1 2.3 2 ZapG-like Z-ring associated protein G-like Domain annotation for each model (and alignments): >> MIEAP Mitochondria-eating protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.7 2 4.7e+03 75 80 .. 91 96 .. 55 125 .. 0.50 2 ! 187.2 0.3 1.8e-58 4.3e-55 1 195 [] 138 337 .] 138 337 .] 0.96 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 2 MIEAP 75 sksLed 80 +k+Le FUN_001579-T1 91 QKELEA 96 122322 PP == domain 2 score: 187.2 bits; conditional E-value: 1.8e-58 MIEAP 1 rpsrlverfaelysqerlealdaldrlielee.....elkqkilfsvvvesFraakealeklklrvkklLsipesgpeesk.sLedavvdylrrtl 90 rps l+er+++l++q+rl+a+d+ld++ +l++ ++k+kilfsv+v++ r+++ +l +++ ++kklL+ip+++ +e++ +L+d ++dy+rrt FUN_001579-T1 138 RPSALIERYDNLFTQTRLDAMDKLDEVESLNQmddsgDIKNKILFSVLVVAHRTVQHSLAEKHRKLKKLLDIPNDEGTEHVrDLQDRITDYFRRTG 233 7899********************9987766666799*************************************87777778************** PP MIEAP 91 dlydvqesvneviealnvntlisfpeevecillssfirecvrvawslviqdPpldleyesdgelfneekhrrshdsdftanlvkyyvWPALvee.. 184 + +v+++ ++v+++l + tl++fpe++ec l+++++ecvr++w+l++q Pp+ +eye+ ++f++++ rs++sd+t +++ky+vWPAL++ FUN_001579-T1 234 AKLKVDSIRRDVSKQL-WTTLYDFPELQECSKLKEYMNECVRLSWMLAVQVPPMSIEYEA--TEFTDKLQGRSMTSDMTKTVIKYHVWPALIDAqt 326 ****************.*******************************************..*******************************999 PP MIEAP 185 gkvlvKGvvvt 195 g vl+KG vvt FUN_001579-T1 327 GHVLYKGTVVT 337 **********8 PP >> Phage_phiTE_211 Phage phiTE_211 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 9.8 5.9e-05 0.14 180 249 .. 39 114 .. 14 121 .. 0.63 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 5.9e-05 Phage_phiTE_211 180 aeeeekksaskeapte....sdkenkeevdeedlt..ksaavqelqkaleakkaelekaeeivkaaeaaekaatek 249 +e e+++ ++++ + e + +e ke v+++d+t k+++ +lq +l +k++ele+a++ vk ++ e+++t+ FUN_001579-T1 39 DETESSARTTDPSLSEseytQAAESKERVTKNDITqqKTDENSNLQRQLSEKQKELEAAQKMVKHLKERERNLTDR 114 22222222222222221111333447777777555228899***************************99997765 PP >> Acyl-CoA_dh_2 Acyl-CoA dehydrogenase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.9 6.7e-05 0.16 23 71 .. 64 114 .. 55 137 .. 0.76 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 6.7e-05 Acyl-CoA_dh_2 23 rervr..asagekladrpatqlalAeaaarldAArllleraaaraealaaa 71 +erv+ + +++k ++++ +q +l e + +l+AA++++++ +r+ +l ++ FUN_001579-T1 64 KERVTknDITQQKTDENSNLQRQLSEKQKELEAAQKMVKHLKERERNLTDR 114 24555777889999**************************99996665444 PP >> Csm1_N Csm1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 10.7 0.00019 0.44 25 68 .. 76 119 .. 55 121 .. 0.85 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00019 Csm1_N 25 lvhENsvLsqkletkdqeiesLkeqlaeleekvkeleerrkkqe 68 + ENs L+++l+ k++e+e+ ++ +++l+e+ ++l +r ++q+ FUN_001579-T1 76 KTDENSNLQRQLSEKQKELEAAQKMVKHLKERERNLTDRLQDQA 119 368**********************************9999886 PP >> PANTS-like Synaptic plasticity regulator PANTS-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 3.3 4.9 1.1e+04 52 55 .. 95 98 .. 55 131 .. 0.61 2 ? 11.4 0.1 0.00019 0.44 19 66 .. 248 295 .. 244 318 .. 0.79 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 4.9 PANTS-like 52 eeaq 55 e+aq FUN_001579-T1 95 EAAQ 98 2222 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00019 PANTS-like 19 gqfknyYryGelksCsekwedfkfClrlkekkeeeaqealrkreeekk 66 + + +Y + el++Cs+ +e ++ C+rl+ + + ++ + ++ e+++ FUN_001579-T1 248 QLWTTLYDFPELQECSKLKEYMNECVRLSWMLAVQVPPMSIEYEATEF 295 557899**********************97777777666666666554 PP >> OmpH Outer membrane protein (OmpH-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 13.5 0.00049 1.1 39 109 .. 54 128 .. 32 134 .. 0.75 2 ? -1.8 0.0 2 4.7e+03 60 72 .. 214 226 .. 188 250 .. 0.49 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00049 OmpH 39 ekelqklqeklq....aeasels.sekeekekelqkkeqelqeqqqkaqqelqkkqqellqpilekvkkaikevak 109 e e+++ +e + ++ ++++ +e+ + +++l +k++el+++q+ + l++++++l+++++++++ +k+ +k FUN_001579-T1 54 ESEYTQAAESKErvtkNDITQQKtDENSNLQRQLSEKQKELEAAQKMV-KHLKERERNLTDRLQDQAQRQLKKGGK 128 555555555555554334334444559999******************.*******************99988666 PP == domain 2 score: -1.8 bits; conditional E-value: 2 OmpH 60 keekekelqkkeq 72 +e ++lq++ + FUN_001579-T1 214 GTEHVRDLQDRIT 226 2333333333333 PP >> TMF_TATA_bd TATA element modulatory factor 1 TATA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 12.8 0.0066 15 20 103 .. 33 117 .. 28 122 .. 0.87 2 ? 3.0 0.0 0.066 1.5e+02 68 103 .. 191 227 .. 183 230 .. 0.84 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0066 TMF_TATA_bd 20 eirrlegElaslkeel.arleaerdeareEivklmkeneelkelkkeleelekelkeleeryettLellGEKsEeveELkaDveD 103 ++ +l+ E +s+ + +l+++ ++E + +++n+ ++++ +e+++l+++l+e+++++e++ ++ + +E+ L + ++D FUN_001579-T1 33 TVTQLDDETESSARTTdPSLSESEYTQAAESKERVTKNDITQQKTDENSNLQRQLSEKQKELEAAQKMVKHLKERERNLTDRLQD 117 5667777776554444157888888899999999*********************************************999998 PP == domain 2 score: 3.0 bits; conditional E-value: 0.066 TMF_TATA_bd 68 elekelkeleeryettLell.GEKsEeveELkaDveD 103 +++ +l+e++++++++L + E +E v +L++ + D FUN_001579-T1 191 TVQHSLAEKHRKLKKLLDIPnDEGTEHVRDLQDRITD 227 677888899999999998853699*********9998 PP >> TMEM120A-B TMEM120A/B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 4.8 0.0013 2.9 27 103 .. 59 136 .. 33 147 .. 0.63 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0013 TMEM120A-B 27 elsklqskc.skeiskqkk.rlkelksslkklkkkvkeeekeaveeleeelkerkaqlkemeallpkknglylklvlGn 103 + +++++++ +++i++qk + ++l+++l++ +k++ e +++v++l+e+ ++ + +l++ ++ kk+g++ l G+ FUN_001579-T1 59 QAAESKERVtKNDITQQKTdENSNLQRQLSEKQKEL-EAAQKMVKHLKERERNLTDRLQDQAQRQLKKGGKFEDLSAGE 136 333333333033444444314566777777777764.567777777777777777888888888888888887776665 PP >> SEEEED Serine-rich region of AP3B1, clathrin-adaptor complex # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 12.7 0.0018 4.1 20 94 .. 16 96 .. 11 126 .. 0.71 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0018 SEEEED 20 SdseseSgSeseee....keeedssedSsedSsseeeseseseseaekkraakrnskakkksdsedeekk..neksktsdS 94 S+ses+ Se++++ + d + +Ss ++ + sese + ae+k+ ++n +++k d + + ++ +ek+k+ + FUN_001579-T1 16 SGSESGDISEEGSDvfdtVTQLDDETESSARTTDPSLSESEYTQAAESKERVTKNDITQQKTDENSNLQRqlSEKQKELEA 96 556666666666654322445555666667777888999999999998888888877777776554433324888887665 PP >> DUF4446 Protein of unknown function (DUF4446) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 5.3 0.0038 8.9 30 81 .. 70 121 .. 56 134 .. 0.83 2 ? -0.1 0.0 0.5 1.2e+03 10 44 .. 182 216 .. 176 250 .. 0.53 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0038 DUF4446 30 kykklmrgkdgknleelleekldeveelkeeveelekeieeleeklkksvqk 81 + + +++++++nl++ l+ek +e+e++++ v++l+++ ++l+++l+ + q+ FUN_001579-T1 70 NDITQQKTDENSNLQRQLSEKQKELEAAQKMVKHLKERERNLTDRLQDQAQR 121 444445667999**********************************998876 PP == domain 2 score: -0.1 bits; conditional E-value: 0.5 DUF4446 10 viillilliilllklkklkkkykklmrgkdgknle 44 + +l++ +++++l + ++k+kkl++ +++ e FUN_001579-T1 182 FSVLVVAHRTVQHSLAEKHRKLKKLLDIPNDEGTE 216 44444444455555555555555555533333322 PP >> ZapG-like Z-ring associated protein G-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 6.1 0.0015 3.4 19 66 .. 73 120 .. 51 136 .. 0.82 2 ? 0.0 0.1 0.51 1.2e+03 14 54 .. 187 232 .. 181 249 .. 0.58 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0015 ZapG-like 19 tnsklkkqkklekelekskaeleeyrqeledHfarsaelleklakdyq 66 t++k+ ++++l+++l ++++ele ++ +++ +r ++l + l+++ q FUN_001579-T1 73 TQQKTDENSNLQRQLSEKQKELEAAQKMVKHLKERERNLTDRLQDQAQ 120 788889999999999999999999887755444566778888887765 PP == domain 2 score: 0.0 bits; conditional E-value: 0.51 ZapG-like 14 lvlrltnskl.kkqkklekele....kskaeleeyrqeledHfars 54 +++r+ +++l +k++kl+k l+ + ++ + ++ + d+f r+ FUN_001579-T1 187 VAHRTVQHSLaEKHRKLKKLLDipndEGTEHVRDLQDRITDYFRRT 232 5566665554145666777665111133334444455555666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (337 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3961 (0.15506); expected 510.9 (0.02) Passed bias filter: 1264 (0.0494813); expected 510.9 (0.02) Passed Vit filter: 150 (0.00587199); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 3199.59 // Query: FUN_001580-T1 [L=334] Description: FUN_001580 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.071 13.3 0.1 0.21 11.8 0.1 1.9 1 zf-C2HC_2 zinc-finger of a C2HC-type 0.11 13.8 1.6 18 6.6 0.2 2.9 3 Occludin_ELL Occludin homology domain 0.17 12.7 0.1 1.2 10.0 0.1 2.3 2 DUF8167_2nd Domain of unknown function (DUF8167) 2nd domain Domain annotation for each model (and alignments): >> zf-C2HC_2 zinc-finger of a C2HC-type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 2.5e-05 0.21 6 17 .. 19 30 .. 19 32 .. 0.91 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 2.5e-05 zf-C2HC_2 6 piCGRkFnpdrL 17 ++C+R+F++d+L FUN_001580-T1 19 YNCSRSFAEDSL 30 79*********9 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 2 1.7e+04 22 33 .. 80 91 .. 75 94 .. 0.72 2 ? 6.0 0.1 0.0033 28 25 68 .. 185 229 .. 163 233 .. 0.81 3 ? 6.6 0.2 0.0021 18 19 67 .. 229 276 .. 224 291 .. 0.83 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 2 Occludin_ELL 22 keYkeLhaelea 33 keY++L + +++ FUN_001580-T1 80 KEYQDLTRIVNQ 91 677777777765 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0033 Occludin_ELL 25 keLhaeleavskkfskleeelkslkegsk.eykkiaeeilqeykk 68 Lha++++++++fsk + ++++++s+ y ki+e +++e+k+ FUN_001580-T1 185 GTLHARVKETAEQFSKALNGFTEHTNSSEaFYIKIHEALKSELKR 229 579*************99999999988887888999999999886 PP == domain 3 score: 6.6 bits; conditional E-value: 0.0021 Occludin_ELL 19 aeykeYkeLhaeleavskkfskleeelkslkegskeykkiaeeilqeyk 67 + + Yk+ ++l+++++kf k ++el+ +++s++ +++++ +y FUN_001580-T1 229 RTVSYYKSALEKLADTTSKFPKSSSELSWTPTRSRKKADLESK-TAQYP 276 5567899999************************999999998.66665 PP >> DUF8167_2nd Domain of unknown function (DUF8167) 2nd domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.33 2.8e+03 24 36 .. 239 251 .. 235 256 .. 0.83 2 ? 10.0 0.1 0.00014 1.2 17 46 .. 259 288 .. 255 291 .. 0.92 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.33 DUF8167_2nd 24 eeLagktllfPrd 36 e+La++t +fP+ FUN_001580-T1 239 EKLADTTSKFPKS 251 78*********87 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00014 DUF8167_2nd 17 pvpeelkeeLagktllfPrdltleeLeerl 46 p ++ k++L+ kt + Pr ++ + Leerl FUN_001580-T1 259 PTRSRKKADLESKTAQYPRAMSGQSLEERL 288 777889***********************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (334 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1611 (0.0630652); expected 510.9 (0.02) Passed bias filter: 887 (0.034723); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3339.00 // Query: FUN_001581-T1 [L=859] Description: FUN_001581 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-06 27.2 0.2 0.00027 19.8 0.2 2.9 1 HSP70 Hsp70 protein Domain annotation for each model (and alignments): >> HSP70 Hsp70 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.2 1.1e-08 0.00027 91 358 .. 356 690 .. 338 742 .. 0.68 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 1.1e-08 HSP70 91 kkengkalvevea.agekfspeqisamvLkklketaeaylgkk....vt....davitvPaYfndaqRqatkdAgkiAGL....nvlR..ivNepT 171 +++n + ve++a +g++ + i a L+ +k+++ + l+++ + + v+tvPa ++ +q ++ A+ AGL n R i ep FUN_001581-T1 356 SEKNLHKDVEIKAaNGKSVRAVTIFAHALTFFKDHVLEELSDQsatrIMeediQWVLTVPAIWKAPAKQFMRTAAYEAGLttlhNPERllIALEPE 451 444444444443315777777777777777777666555554433332212226799*******99999999999999994444344533567999 PP HSP70 172 AaalaY.Gldkkd..........................kernvlvyDlGggtfdvSilele..eGvfevkaTngDthlGGedfDealvdylveef 238 Aa++ l +d ++ lv+D Gggt d + el+ G++e + + G De+ l + f FUN_001581-T1 452 AASIYCrKLRLRDciwaeetkrrsntplkidslvrdefqENTRYLVVDCGGGTVDLTVHELDsqTGTLEELHRGTGGACGATGVDEQFELLLKKIF 547 999943246666699999999**************999889999**************9987448****998888888999888888877777777 PP HSP70 239 kkkegidlskdkka.lqrlkeaaekaKkeLSsskqt..einleietvdedgkd..............lsek.....lsR...akfeelvedllert 309 k+ + +k++ a + l a e K++ S +k + +i+l++ +d ++k+ ++k + R +++l +++l+r+ FUN_001581-T1 548 GKDFIGQFKKKRPAgWVDLMIAFEAKKRTASRNKTSplNISLPYSFIDYHKKHkgssiesavkkfgdANVKwssqgMLRiapGTMKQLFDPVLNRI 643 777555555554333778888888888888876655223444444333222221111000000000022221111233322256889999999999 PP HSP70 310 lepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfgkepsksv 358 +e ve++ + k ++++ + lvGG + P +q++++e+f+ + + + FUN_001581-T1 644 IEHVENLTSRE--KLKDLHFLFLVGGFAESPLLQSAIREVFDSKMKVII 690 99999987655..5679************************97765544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (859 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 899 (0.0351928); expected 510.9 (0.02) Passed bias filter: 760 (0.0297514); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.43u 0.40s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 8217.07 // Query: FUN_001582-T1 [L=111] Description: FUN_001582 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-20 74.4 0.4 1.2e-20 74.3 0.4 1.1 1 TMEM_230_134 Transmembrane proteins 230/134 ------ inclusion threshold ------ 0.16 12.4 6.9 6.4 7.3 7.1 2.1 2 DUF8178 Family of unknown function (DUF8178) 0.63 10.1 1.3 0.8 9.8 1.3 1.1 1 Tetraspanin Tetraspanin family Domain annotation for each model (and alignments): >> TMEM_230_134 Transmembrane proteins 230/134 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.3 0.4 1.4e-24 1.2e-20 40 119 .] 28 110 .. 5 110 .. 0.84 Alignments for each domain: == domain 1 score: 74.3 bits; conditional E-value: 1.4e-24 TMEM_230_134 40 hPkvkknrkvvlaallLlllGlvLlllgvvvlvepseGv.ssavf..lvlGlllfiPGvYhvvyiylavrGrrGykFaklPlf 119 +P k ++++ +a++L +G+vLl++g +++++ + + + l+lG l+fiPG+Yhv+++y+a++G+rGy+F+ +P+f FUN_001582-T1 28 KPPPKVPWRAIFLATFLFSVGTVLLVIGSLLFTGYIDVKyADRTYpmLILGSLMFIPGFYHVRIAYYAWKGYRGYSFDDIPDF 110 5566778*************************998543313445555**********************************98 PP >> DUF8178 Family of unknown function (DUF8178) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 7.1 0.00075 6.4 11 51 .. 47 87 .. 41 87 .. 0.89 2 ? 6.6 0.4 0.0012 10 15 27 .. 74 86 .. 71 93 .. 0.88 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.00075 DUF8178 11 iGivLmvVGtllflPgvlpgasqlvtvaLvvAaalLtaGTY 51 +G vL+v+G+llf + ++++ + +L+ ++++ + G Y FUN_001582-T1 47 VGTVLLVIGSLLFTGYIDVKYADRTYPMLILGSLMFIPGFY 87 9************9999999999999999999998887765 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0012 DUF8178 15 LmvVGtllflPgv 27 +++ G+l f+Pg FUN_001582-T1 74 MLILGSLMFIPGF 86 789********97 PP >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 1.3 9.4e-05 0.8 6 63 .. 38 87 .. 35 98 .. 0.73 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 9.4e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 6 fllnllflllGllllavGvwlksleaassalsesseaaalipvllivlGaviflvgfl 63 ++l ++++ +G +ll++G +l ++ + + ++ + ++ +++lG+++f+ gf FUN_001582-T1 38 IFLATFLFSVGTVLLVIGSLL-----FTGYIDVKYADRTYP---MLILGSLMFIPGFY 87 566666777777777777344.....456666666777777...**********9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (111 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 721 (0.0282247); expected 510.9 (0.02) Passed bias filter: 481 (0.0188295); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.34s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1130.21 // Query: FUN_001583-T1 [L=898] Description: FUN_001583 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.17 12.5 0.2 0.44 11.2 0.2 1.6 1 Adipogenin Adipogenin 0.22 12.4 3.8 0.55 11.2 1.6 3.0 2 Ins134_P3_kin_N Inositol 1,3,4-trisphosphate 5/6-kinase pre- 3.1 8.8 0.0 3.1 8.8 0.0 6.4 5 Ctr Ctr copper transporter family 3.6 7.6 5.7 1.4 8.9 0.1 3.4 3 UBM Ubiquitin binding region 5.1 7.7 5.0 8 7.1 5.0 1.2 1 DUF5957 Family of unknown function (DUF5957) Domain annotation for each model (and alignments): >> Adipogenin Adipogenin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.2 8.6e-05 0.44 14 45 .. 23 52 .. 18 61 .. 0.78 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 8.6e-05 Adipogenin 14 fsflvfwlclpvalllfllivwlrfllsqdse 45 + flvf lcl v+++l ll+ r++l q e FUN_001583-T1 23 YVFLVFLLCLVVGFILGLLL--ARYVLRQLEE 52 78*************97776..4666666444 PP >> Ins134_P3_kin_N Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 2.6 1.3e+04 28 52 .. 283 306 .. 275 320 .. 0.73 2 ? 11.2 1.6 0.00011 0.55 9 44 .. 516 553 .. 512 581 .. 0.78 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 2.6 Ins134_P3_kin_N 28 ielvkldesrplsEqGpldiiiHkl 52 +++ ++d+ r +Eq + +++H FUN_001583-T1 283 MNMLEVDK-RLAEEQNRQAMVLHER 306 56666664.5668999999999975 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00011 Ins134_P3_kin_N 9 kkiksflqpklvela..rkrgielvkldesrplsEqGp 44 k++ ++q+kl e+ ++r +e ++++sr ++EqG+ FUN_001583-T1 516 EKQRAIIQEKLQERKqrKEREMEQQRVEQSRMVEEQGK 553 699*********986224688999*************8 PP >> Ctr Ctr copper transporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.0006 3.1 17 88 .. 15 98 .. 7 185 .. 0.66 2 ? 0.5 0.2 0.21 1.1e+03 37 83 .. 178 225 .. 159 287 .. 0.51 3 ? -2.5 0.1 1.8 9.1e+03 70 77 .. 320 327 .. 276 393 .. 0.50 4 ? -9.7 11.4 5 2.6e+04 52 52 .. 496 496 .. 354 566 .. 0.67 5 ? -11.9 15.2 5 2.6e+04 107 107 .. 654 654 .. 579 868 .. 0.71 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0006 Ctr 17 wkitstgafagsciglfllavlyeflkalrarlereydakla.rkkeaksrsasaaskssssesseeessek.............e 88 k+++ g++++ +++l+l++ + +l r l r+++++ + r+++++s++ ++ +++ e+++e s +k + FUN_001583-T1 15 AKPDTLGGYVFLVFLLCLVVGFILGLLLARYVL-RQLEEQYStRRSKSHSAAIVLENGYEELEKKTE-SPKKlesnriapmsvpsN 98 579999*****9999999999999999777777.555555531333333333333333333222222.222234444444433330 PP == domain 2 score: 0.5 bits; conditional E-value: 0.21 Ctr 37 vlyeflkalrarlereydakl..a........rkkeaksrsasaaskssssesseee 83 +++ fl ++r+++ +++ l + + ++a+++ +++e++ ++ FUN_001583-T1 178 MILSFLV-SKSRITEVFKRDLlaKyeqglediN--------KNAKEEMKAKEQELRT 225 4445544.5555555555555321111111221........1111111111111111 PP == domain 3 score: -2.5 bits; conditional E-value: 1.8 Ctr 70 aaskssss 77 ++++++++ FUN_001583-T1 320 VNQQEKDE 327 22211111 PP == domain 4 score: -9.7 bits; conditional E-value: 5 Ctr 52 e 52 FUN_001583-T1 496 L 496 1 PP == domain 5 score: -11.9 bits; conditional E-value: 5 Ctr 107 v 107 + FUN_001583-T1 654 H 654 0 PP >> UBM Ubiquitin binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.1 0.31 1.6e+03 22 30 .. 474 482 .. 473 485 .. 0.87 2 ? 8.9 0.1 0.00028 1.4 17 33 .. 565 581 .. 563 583 .. 0.88 3 ? -3.9 0.3 3 1.5e+04 22 32 .. 694 704 .. 694 706 .. 0.78 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.31 UBM 22 ReEVLaqqd 30 ReEVL ++ FUN_001583-T1 474 REEVLFEHI 482 9****9986 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00028 UBM 17 LPpdLReEVLaqqdeer 33 L ++LR +V++++d+ + FUN_001583-T1 565 LAEELRKQVMMEHDQNM 581 789***********975 PP == domain 3 score: -3.9 bits; conditional E-value: 3 UBM 22 ReEVLaqqdee 32 ReE++ qq e+ FUN_001583-T1 694 REEIIKQQNEA 704 99*99888776 PP >> DUF5957 Family of unknown function (DUF5957) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 5.0 0.0016 8 2 21 .. 25 44 .. 24 47 .. 0.90 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0016 DUF5957 2 llavllgligGFilGilLSe 21 +l+ ll l++GFilG+lL+ FUN_001583-T1 25 FLVFLLCLVVGFILGLLLAR 44 8899**************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (898 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4809 (0.188256); expected 510.9 (0.02) Passed bias filter: 676 (0.0264631); expected 510.9 (0.02) Passed Vit filter: 163 (0.0063809); expected 25.5 (0.001) Passed Fwd filter: 38 (0.00148757); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.81u 0.40s 00:00:01.21 Elapsed: 00:00:00.45 # Mc/sec: 8107.07 // Query: FUN_001584-T1 [L=129] Description: FUN_001584 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 711 (0.0278332); expected 510.9 (0.02) Passed bias filter: 529 (0.0207086); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1282.35 // Query: FUN_001585-T1 [L=616] Description: FUN_001585 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-20 74.2 0.2 4e-20 72.3 0.2 2.0 1 Mab-21_C Mab-21 protein HhH/H2TH-like domain 6.2e-07 30.1 0.4 1.3e-06 29.1 0.1 1.6 2 Mab-21 Mab-21 protein nucleotidyltransferase domai 7.4e-06 26.7 0.2 0.16 12.8 0.0 3.0 3 ANAPC3 Anaphase-promoting complex, cyclosome, subu 1.4e-05 25.8 0.0 0.17 12.7 0.0 3.5 4 TPR_19 Tetratricopeptide repeat 0.00048 20.7 0.0 0.11 13.1 0.0 2.8 2 TPR_12 Tetratricopeptide repeat 0.00063 20.7 0.1 0.19 13.0 0.0 4.1 4 TPR_6 Tetratricopeptide repeat 0.0024 18.3 0.1 0.13 12.9 0.0 2.9 2 TPR_7 Tetratricopeptide repeat 0.0041 18.2 1.0 1 10.8 0.0 4.0 3 TPR_14 Tetratricopeptide repeat 0.0046 17.5 0.1 0.059 14.0 0.0 2.6 2 TPR_8 Tetratricopeptide repeat ------ inclusion threshold ------ 0.013 16.1 0.3 0.84 10.4 0.0 3.2 3 TPR_2 Tetratricopeptide repeat 0.018 15.3 0.6 0.47 10.8 0.0 3.1 3 TPR_1 Tetratricopeptide repeat 0.032 14.1 0.0 0.11 12.4 0.0 1.8 2 TPR_NUP160_120_M NUP160/120 middle TPR 0.033 15.1 0.1 2.1 9.4 0.0 3.1 3 TPR_16 Tetratricopeptide repeat 0.11 13.3 0.1 55 4.8 0.2 3.3 3 PPR PPR repeat 0.25 11.9 0.6 36 5.0 0.1 3.1 3 TPR_10 Tetratricopeptide repeat 0.26 11.2 0.1 5.8 6.8 0.0 2.1 2 Baculo_PP31 Baculovirus 33KDa late protein (PP31) Domain annotation for each model (and alignments): >> Mab-21_C Mab-21 protein HhH/H2TH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.3 0.2 2.5e-23 4e-20 5 101 .. 185 276 .. 181 277 .. 0.86 Alignments for each domain: == domain 1 score: 72.3 bits; conditional E-value: 2.5e-23 Mab-21_C 5 clrllkklkekkkrdvkkeleklksyhlktlllwecekkpddseWeekklkerllellekLkkclrkrklphyFipklnLleelskkeldalakkv 100 c+ +k l + ke + lksyhlk++l+w cek +++ W+ ++l++ +l ll++L +clr+++lphyF+p+lnL+e l+k++ld ++k+ FUN_001585-T1 185 CYLAVKAL---YFME-LKEPTGLKSYHLKMILFWVCEKT-PSNLWTMNSLGRGFLVLLDELISCLREGRLPHYFVPELNLIELLKKEDLDVWVRKL 275 55556666...2222.2344569****************.99************************************************999988 PP Mab-21_C 101 e 101 e FUN_001585-T1 276 E 276 6 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.1 0.1 8.3e-10 1.3e-06 120 192 .. 102 172 .. 67 176 .. 0.84 2 ? -3.4 0.0 7.6 1.2e+04 65 113 .. 378 411 .. 353 428 .. 0.60 Alignments for each domain: == domain 1 score: 29.1 bits; conditional E-value: 8.3e-10 Mab-21 120 eqysVdlvpaielkasWpksasnwprcl..krwpsqkvlekiksegfhlvakssykdqdekeedsWrlSFseaEk 192 ++ d+v a++ + Wpk ++w +++ ++wps ++++ + + g+hlv+k++ + ++ + Wrl Fs E FUN_001585-T1 102 LPLTLDYVHAVC-VD-WPKEVNEWRERSrpSNWPSSELIDDVIKTGIHLVPKPHA--LSLQKDVEWRLAFSLPEI 172 456778888875.56.9*******87652268********************888..67************9885 PP == domain 2 score: -3.4 bits; conditional E-value: 7.6 Mab-21 65 aegylsaaKvlsrfqslvekalkklekeievndetlklsykrkgpavtv 113 +eg l + K+l rf +++ + +++ ++++p +++ FUN_001585-T1 378 MEGHLAKVKLLIRFMDALVQYVSDN---------------EEESPSHRM 411 5666666666666666666666652...............223444443 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.0 0.00055 0.88 17 49 .. 452 484 .. 440 497 .. 0.71 2 ! 12.8 0.0 0.0001 0.16 26 81 .. 531 593 .. 528 594 .. 0.93 3 ! 7.6 0.1 0.0043 6.8 25 54 .. 570 600 .. 554 609 .. 0.76 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00055 ANAPC3 17 aaepespedayllAqclflngqykrAyellrka 49 ++ ++ ++a+l+A+ l+++ + ++A+ +l + FUN_001585-T1 452 SSVYHDTSSALLFANFLYEQRRLEEAISILTTI 484 455567788888888888888888888888877 PP == domain 2 score: 12.8 bits; conditional E-value: 0.0001 ANAPC3 26 ayllAqclflngqykrAyellrka.klneksl......gcryllAqcllkLkkykeAldaLek 81 +yll c+ ngq rA +ll + ++ +s ++++ll+ c+l+ ++ ++Al+++++ FUN_001585-T1 531 LYLLISCFVDNGQTGRARDLLPELfAERDRSSkefsygDSCVLLGYCYLRFGEKEQALSMFKE 593 79*********************998988888899999999*****************99987 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0043 ANAPC3 25 dayllAqclflngqykrAyellrka.klnek 54 + ll++c+++ g+ ++A+ +++a ++ + FUN_001585-T1 570 SCVLLGYCYLRFGEKEQALSMFKEAvDEHAS 600 5568899999999999999999999555444 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 4.8 7.7e+03 34 60 .. 308 334 .. 307 340 .. 0.80 2 ! 8.5 0.0 0.0022 3.4 28 51 .. 461 484 .. 443 489 .. 0.89 3 ? 1.6 0.0 0.31 5e+02 28 51 .. 531 554 .. 530 566 .. 0.82 4 ! 12.7 0.0 0.00011 0.17 3 62 .. 540 606 .. 538 609 .. 0.83 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 4.8 TPR_19 34 allalgrldeAealLaalpaadpddpe 60 al ++r+++ ++l+a+ ++ +d+ + FUN_001585-T1 308 ALKDTNRYARGIRLVARHSESGDDNKA 334 667889999999999999999888765 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0022 TPR_19 28 rllLArallalgrldeAealLaal 51 +ll A++l+++ rl+eA+ +L ++ FUN_001585-T1 461 ALLFANFLYEQRRLEEAISILTTI 484 5789*****************987 PP == domain 3 score: 1.6 bits; conditional E-value: 0.31 TPR_19 28 rllLArallalgrldeAealLaal 51 ++lL+ + + +g+ +A+ lL +l FUN_001585-T1 531 LYLLISCFVDNGQTGRARDLLPEL 554 57899999*********9999665 PP == domain 4 score: 12.7 bits; conditional E-value: 0.00011 TPR_19 3 aegdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaadpdd.peya 62 ++g++ +A+ lL ++ ae + + ++lL+ ++l+ g+ ++A +++++ ++++ d y+ FUN_001585-T1 540 DNGQTGRARDLLPELFAERDRsskefsYGDSCVLLGYCYLRFGEKEQALSMFKEAVDEHASDaGKYW 606 688889999999998888444555677888899*************************999866555 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.037 60 3 27 .. 459 482 .. 457 486 .. 0.84 2 ! 13.1 0.0 7.2e-05 0.11 8 73 .. 533 596 .. 528 596 .. 0.78 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.037 TPR_12 3 atalnnlAavlrrlgrydeAlelle 27 +al A++l+++ r++eA+++l FUN_001585-T1 459 SSAL-LFANFLYEQRRLEEAISILT 482 5666.89**************9875 PP == domain 2 score: 13.1 bits; conditional E-value: 7.2e-05 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqale 73 l ++ ++g+ A++ll + + + r+ + + + + +Lg +yl+ g+ e+Al+++++a++ FUN_001585-T1 533 LLISCFVDNGQTGRARDLLPELFAERDRSSKEFS--YGDSCVLLGYCYLRFGEKEQALSMFKEAVD 596 6667777777777777777777777777755555..8888889********************975 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 4.5 7.3e+03 2 11 .. 338 347 .. 337 352 .. 0.84 2 ? 0.9 0.0 0.81 1.3e+03 9 26 .. 467 484 .. 461 487 .. 0.81 3 ? -0.1 0.0 1.7 2.8e+03 3 23 .. 531 551 .. 530 554 .. 0.91 4 ! 13.0 0.0 0.00012 0.19 5 30 .. 573 598 .. 572 600 .. 0.92 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 4.5 TPR_6 2 Allklalsyl 11 All ++ +y FUN_001585-T1 338 ALLEIGFCYA 347 9*******97 PP == domain 2 score: 0.9 bits; conditional E-value: 0.81 TPR_6 9 sylelgdkdeAkaalqrl 26 ++e+ + +eA+++l + FUN_001585-T1 467 FLYEQRRLEEAISILTTI 484 578888*******99866 PP == domain 3 score: -0.1 bits; conditional E-value: 1.7 TPR_6 3 llklalsylelgdkdeAkaal 23 l+ l ++ g++ +A+++l FUN_001585-T1 531 LYLLISCFVDNGQTGRARDLL 551 899999****99*****9986 PP == domain 4 score: 13.0 bits; conditional E-value: 0.00012 TPR_6 5 klalsylelgdkdeAkaalqrlikkY 30 l+++yl+ g+k++A++++++ ++++ FUN_001585-T1 573 LLGYCYLRFGEKEQALSMFKEAVDEH 598 59******99***********99987 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.28 4.5e+02 6 24 .. 465 483 .. 462 488 .. 0.85 2 ! 12.9 0.0 8.2e-05 0.13 1 32 [. 570 599 .. 570 603 .. 0.86 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.28 TPR_7 6 ariyrklGdydeAirlyer 24 a+++ +++ +eAi++++ FUN_001585-T1 465 ANFLYEQRRLEEAISILTT 483 5677788********9986 PP == domain 2 score: 12.9 bits; conditional E-value: 8.2e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdp 32 ++++L+ +y + G+ ++A++++++ a++++ FUN_001585-T1 570 SCVLLGYCYLRFGEKEQALSMFKE--AVDEHA 599 699*********************..666554 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.65 1e+03 6 24 .. 463 481 .. 460 484 .. 0.88 2 ? 0.4 0.0 1.5 2.3e+03 4 24 .. 531 551 .. 530 560 .. 0.88 3 ! 10.8 0.0 0.00063 1 6 38 .. 573 606 .. 571 610 .. 0.85 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.65 TPR_14 6 alarallalGdpdeAlell 24 + a++l ++ +++eA+ +l FUN_001585-T1 463 LFANFLYEQRRLEEAISIL 481 67999***********987 PP == domain 2 score: 0.4 bits; conditional E-value: 1.5 TPR_14 4 wlalarallalGdpdeAlell 24 +++l+ ++ +G++ +A++ll FUN_001585-T1 531 LYLLISCFVDNGQTGRARDLL 551 578889999*********997 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00063 TPR_14 6 alarallalGdpdeAlelleralaldPddp.eaw 38 +l++ +l+ G+ ++Al ++++a+ + +d+ +w FUN_001585-T1 573 LLGYCYLRFGEKEQALSMFKEAVDEHASDAgKYW 606 68999********************998862555 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 1.2 1.9e+03 6 24 .. 463 481 .. 459 484 .. 0.82 2 ! 14.0 0.0 3.7e-05 0.059 2 29 .. 569 596 .. 568 597 .. 0.94 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 1.2 TPR_8 6 nlGliylklgdyeeAkeyy 24 + ++ + ++ ++eeA+ ++ FUN_001585-T1 463 LFANFLYEQRRLEEAISIL 481 5678889999*****9876 PP == domain 2 score: 14.0 bits; conditional E-value: 3.7e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekale 29 +++++lG++yl+ g++e+A +++a++ FUN_001585-T1 569 DSCVLLGYCYLRFGEKEQALSMFKEAVD 596 689***********************85 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 4.9 7.8e+03 3 17 .. 338 352 .. 337 353 .. 0.86 2 ? 1.6 0.0 0.34 5.5e+02 8 22 .. 465 479 .. 464 483 .. 0.86 3 ? 10.4 0.0 0.00053 0.84 4 29 .. 571 596 .. 568 598 .. 0.90 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 4.9 TPR_2 3 alynlGlayyklgdy 17 al + G +y+ g++ FUN_001585-T1 338 ALLEIGFCYAVEGKF 352 78899****999987 PP == domain 2 score: 1.6 bits; conditional E-value: 0.34 TPR_2 8 GlayyklgdyeeAle 22 ++ +y++ ++eeA+ FUN_001585-T1 465 ANFLYEQRRLEEAIS 479 6779*********95 PP == domain 3 score: 10.4 bits; conditional E-value: 0.00053 TPR_2 4 lynlGlayyklgdyeeAleayekAle 29 + lG++y++ g+ e+Al +++A+ FUN_001585-T1 571 CVLLGYCYLRFGEKEQALSMFKEAVD 596 678*********************85 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 1.1 1.8e+03 3 17 .. 338 352 .. 336 352 .. 0.88 2 ? -0.1 0.0 0.87 1.4e+03 8 21 .. 465 478 .. 465 479 .. 0.88 3 ? 10.8 0.0 0.0003 0.47 5 28 .. 572 595 .. 569 598 .. 0.90 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.1 TPR_1 3 alynlGnayfklgky 17 al +G +y gk+ FUN_001585-T1 338 ALLEIGFCYAVEGKF 352 8999******99997 PP == domain 2 score: -0.1 bits; conditional E-value: 0.87 TPR_1 8 GnayfklgkydeAl 21 +n ++++ +++eA+ FUN_001585-T1 465 ANFLYEQRRLEEAI 478 57799********9 PP == domain 3 score: 10.8 bits; conditional E-value: 0.0003 TPR_1 5 ynlGnayfklgkydeAleyyekAL 28 lG++y++ g+ ++Al +++A+ FUN_001585-T1 572 VLLGYCYLRFGEKEQALSMFKEAV 595 579*******************97 PP >> TPR_NUP160_120_M NUP160/120 middle TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.1 3.4e+03 31 62 .. 521 552 .. 499 566 .. 0.78 2 ? 12.4 0.0 6.6e-05 0.11 39 71 .. 569 601 .. 556 616 .] 0.79 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.1 TPR_NUP160_120_M 31 swcewnsasrkfllavslLelgeaekaldlfl 62 ++ w + +ll ++++++g++ +a dl+ FUN_001585-T1 521 EVEYWVPTFTLYLLISCFVDNGQTGRARDLLP 552 55567777888999999999999999998875 PP == domain 2 score: 12.4 bits; conditional E-value: 6.6e-05 TPR_NUP160_120_M 39 srkfllavslLelgeaekaldlfleaakgvlke 71 ll+ ++L++ge+e+al++f+ea+++ +++ FUN_001585-T1 569 DSCVLLGYCYLRFGEKEQALSMFKEAVDEHASD 601 56689**********************999887 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 9.5 1.5e+04 6 24 .. 308 326 .. 307 342 .. 0.62 2 ? 1.8 0.0 0.3 4.8e+02 38 52 .. 465 479 .. 449 486 .. 0.82 3 ? 9.4 0.0 0.0013 2.1 8 64 .. 539 601 .. 532 602 .. 0.71 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 9.5 TPR_16 6 aalaagdyddAaaaleaal 24 a+ + ++y++ +++ ++ FUN_001585-T1 308 ALKDTNRYARGIRLVARHS 326 5667788888887665544 PP == domain 2 score: 1.8 bits; conditional E-value: 0.3 TPR_16 38 GlallrqgrlaeAaa 52 + l++q+rl+eA+ FUN_001585-T1 465 ANFLYEQRRLEEAIS 479 778999999999985 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0013 TPR_16 8 laagdyddAaaaleaalrrn.PeaaaAllg.....lGlallrqgrlaeAaaayraalraapgd 64 +++g+ +A+ +l ++ + + ++ ++++g lG+++lr g+ + A+ +++a+++ ++d FUN_001585-T1 539 VDNGQTGRARDLLPELFAERdRSSKEFSYGdscvlLGYCYLRFGEKEQALSMFKEAVDEHASD 601 66777777777774444444455555555333333**********************998887 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 5 7.9e+03 14 23 .. 472 481 .. 468 485 .. 0.83 2 ? 4.2 0.0 0.052 84 5 23 .. 533 551 .. 529 556 .. 0.87 3 ? 4.8 0.2 0.034 55 9 26 .. 577 594 .. 571 598 .. 0.89 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 5 PPR 14 GkleeAlelf 23 ++leeA++++ FUN_001585-T1 472 RRLEEAISIL 481 789****987 PP == domain 2 score: 4.2 bits; conditional E-value: 0.052 PPR 5 slIsgycknGkleeAlelf 23 lIs+++ nG+ A +l+ FUN_001585-T1 533 LLISCFVDNGQTGRARDLL 551 69*************9998 PP == domain 3 score: 4.8 bits; conditional E-value: 0.034 PPR 9 gycknGkleeAlelfkeM 26 +y + G+ e Al++fke FUN_001585-T1 577 CYLRFGEKEQALSMFKEA 594 899*************96 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 8.7 1.4e+04 2 10 .. 223 231 .. 223 231 .. 0.85 2 ? 5.0 0.1 0.022 36 8 23 .. 464 479 .. 458 481 .. 0.82 3 ? 3.7 0.0 0.057 91 8 30 .. 574 596 .. 569 598 .. 0.86 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 8.7 TPR_10 2 asslnnLan 10 ++++n L++ FUN_001585-T1 223 LWTMNSLGR 231 689****96 PP == domain 2 score: 5.0 bits; conditional E-value: 0.022 TPR_10 8 LanalraqgryeeAee 23 an l++q+r+eeA FUN_001585-T1 464 FANFLYEQRRLEEAIS 479 69************76 PP == domain 3 score: 3.7 bits; conditional E-value: 0.057 TPR_10 8 LanalraqgryeeAeelleeala 30 L+ + + g+ e A+ +++ea++ FUN_001585-T1 574 LGYCYLRFGEKEQALSMFKEAVD 596 66668999*************86 PP >> Baculo_PP31 Baculovirus 33KDa late protein (PP31) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.09 1.4e+02 70 93 .. 121 144 .. 120 150 .. 0.89 2 ? 6.8 0.0 0.0036 5.8 104 180 .. 389 471 .. 379 504 .. 0.81 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.09 Baculo_PP31 70 NswytKirksewpnShtmWnlvKs 93 N w ++ r s+wp+S+ + +++K+ FUN_001585-T1 121 NEWRERSRPSNWPSSELIDDVIKT 144 899*************99999987 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0036 Baculo_PP31 104 FdfmeklgksievkkssssstesnkkkkknskkvelnveeikesnekRs....klYnEFyrvlketfkngsaPa..ssfiYde 180 fm+ l + + ++++s s++ k + ++ + +++++ es ++R+ k Y+ F ++++ ++++ s+ + f+Y++ FUN_001585-T1 389 IRFMDALVQYVSDNEEESPSHRMMMMVKISLARLQHEAANVTESPSERDsfltKAYEGFTKIVSSVYHDTSSALlfANFLYEQ 471 5699999999999999999999999999999*****************6444478************9877653224566663 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (616 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 658 (0.0257585); expected 510.9 (0.02) Passed bias filter: 583 (0.0228225); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5931.57 // Query: FUN_001585-T2 [L=684] Description: FUN_001585 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-20 73.5 0.1 6.1e-20 71.7 0.1 2.0 1 Mab-21_C Mab-21 protein HhH/H2TH-like domain 7.4e-08 33.2 0.1 1.8e-07 31.9 0.1 1.6 1 Mab-21 Mab-21 protein nucleotidyltransferase domai 9.8e-06 26.3 0.2 0.2 12.5 0.0 3.0 3 ANAPC3 Anaphase-promoting complex, cyclosome, subu 2e-05 25.3 0.0 0.2 12.5 0.0 3.4 4 TPR_19 Tetratricopeptide repeat 0.00073 20.2 0.0 0.13 12.9 0.0 2.7 2 TPR_12 Tetratricopeptide repeat 0.00098 20.1 0.1 0.21 12.8 0.0 4.0 4 TPR_6 Tetratricopeptide repeat 0.0031 18.0 0.1 0.15 12.7 0.0 2.9 2 TPR_7 Tetratricopeptide repeat 0.0057 17.7 0.8 1.2 10.6 0.0 3.9 3 TPR_14 Tetratricopeptide repeat 0.0059 17.2 0.1 0.067 13.9 0.0 2.5 2 TPR_8 Tetratricopeptide repeat ------ inclusion threshold ------ 0.017 15.7 0.2 0.95 10.2 0.0 3.1 3 TPR_2 Tetratricopeptide repeat 0.024 14.9 0.6 0.53 10.7 0.0 3.0 3 TPR_1 Tetratricopeptide repeat 0.039 13.8 0.0 0.13 12.1 0.0 1.8 2 TPR_NUP160_120_M NUP160/120 middle TPR 0.046 14.7 0.1 2.4 9.2 0.0 3.0 3 TPR_16 Tetratricopeptide repeat 0.14 13.0 0.1 62 4.6 0.2 3.4 3 PPR PPR repeat Domain annotation for each model (and alignments): >> Mab-21_C Mab-21 protein HhH/H2TH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.7 0.1 3.3e-23 6.1e-20 22 101 .. 266 344 .. 249 345 .. 0.86 Alignments for each domain: == domain 1 score: 71.7 bits; conditional E-value: 3.3e-23 Mab-21_C 22 keleklksyhlktlllwecekkpddseWeekklkerllellekLkkclrkrklphyFipklnLleelskkeldalakkve 101 ke + l+syhlk++l+w cek +++ W+ ++l++ +l ll++L +clr+++lphyF+p+lnL+e l+k++ld ++k+e FUN_001585-T2 266 KEPAGLQSYHLKMILFWVCEKT-PSNVWTMNSLGRGFLVLLDELISCLREGRLPHYFVPELNLIELLKKEDLDVWVRKLE 344 344559****************.99************************************************9999886 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.9 0.1 1e-10 1.8e-07 108 192 .. 160 240 .. 114 244 .. 0.81 Alignments for each domain: == domain 1 score: 31.9 bits; conditional E-value: 1e-10 Mab-21 108 gpavtvaietseeqysVdlvpaielkasWpksasnwprcl..krwpsqkvlekiksegfhlvakssykdqdekeedsWrlSFseaEk 192 a+ ++i e + d++pa+++ + Wpk ++w +++ ++wps ++++ + + g+hlv+k++ + ++ + Wrl Fs E FUN_001585-T2 160 RAAMLLEIR--ELPLKLDYIPAVCV-D-WPKEVNEWRERSrpSNWPSSELIDDVIKTGIHLVPKPHA--LSLQKDVEWRLTFSLPEI 240 555555555..456899*****965.6.9*******87652268********************888..67************9885 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.0 0.00055 1 17 49 .. 520 552 .. 508 565 .. 0.71 2 ! 12.5 0.0 0.00011 0.2 26 81 .. 599 661 .. 598 662 .. 0.93 3 ! 7.5 0.0 0.0041 7.4 25 53 .. 638 667 .. 621 676 .. 0.74 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00055 ANAPC3 17 aaepespedayllAqclflngqykrAyellrka 49 ++ ++ ++a+l+A+ l+++ + ++A+ +l + FUN_001585-T2 520 SSVYHDTSSALLFANFLYEQRRLEEAISILTTI 552 455567788888888888888888888888877 PP == domain 2 score: 12.5 bits; conditional E-value: 0.00011 ANAPC3 26 ayllAqclflngqykrAyellrka.klneksl......gcryllAqcllkLkkykeAldaLek 81 +yll c+ ngq rA +ll + ++ +s ++++ll+ c+l+ ++ ++Al+++++ FUN_001585-T2 599 LYLLISCFVDNGQTGRARDLLPELfAERDRSSkefsygDSCVLLGYCYLRFGEKEQALSMFKE 661 79*********************998988888899999999*****************99987 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0041 ANAPC3 25 dayllAqclflngqykrAyellrka.klne 53 + ll++c+++ g+ ++A+ +++a ++ FUN_001585-T2 638 SCVLLGYCYLRFGEKEQALSMFKEAvDEHA 667 456789999999999999999999955544 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 4.7 8.7e+03 34 60 .. 376 402 .. 375 408 .. 0.80 2 ! 8.4 0.0 0.0021 3.9 28 51 .. 529 552 .. 511 557 .. 0.89 3 ? 1.4 0.0 0.31 5.6e+02 28 51 .. 599 622 .. 598 634 .. 0.82 4 ! 12.5 0.0 0.00011 0.2 3 62 .. 608 674 .. 606 677 .. 0.82 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 4.7 TPR_19 34 allalgrldeAealLaalpaadpddpe 60 al ++r+++ ++l+a+ ++ +d+ + FUN_001585-T2 376 ALKDTNRYARGIRLVARHSESGDDNKA 402 667889999999999999999888765 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0021 TPR_19 28 rllLArallalgrldeAealLaal 51 +ll A++l+++ rl+eA+ +L ++ FUN_001585-T2 529 ALLFANFLYEQRRLEEAISILTTI 552 5789*****************987 PP == domain 3 score: 1.4 bits; conditional E-value: 0.31 TPR_19 28 rllLArallalgrldeAealLaal 51 ++lL+ + + +g+ +A+ lL +l FUN_001585-T2 599 LYLLISCFVDNGQTGRARDLLPEL 622 57899999*********9999665 PP == domain 4 score: 12.5 bits; conditional E-value: 0.00011 TPR_19 3 aegdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaadpdd.peya 62 ++g++ +A+ lL ++ ae + + ++lL+ ++l+ g+ ++A +++++ ++++ d y+ FUN_001585-T2 608 DNGQTGRARDLLPELFAERDRsskefsYGDSCVLLGYCYLRFGEKEQALSMFKEAVDEHASDaGKYW 674 678889999999998888444555677888899*************************999856555 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.037 67 3 27 .. 527 550 .. 525 554 .. 0.84 2 ! 12.9 0.0 7.2e-05 0.13 8 73 .. 601 664 .. 596 664 .. 0.78 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.037 TPR_12 3 atalnnlAavlrrlgrydeAlelle 27 +al A++l+++ r++eA+++l FUN_001585-T2 527 SSAL-LFANFLYEQRRLEEAISILT 550 5666.89**************9875 PP == domain 2 score: 12.9 bits; conditional E-value: 7.2e-05 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqale 73 l ++ ++g+ A++ll + + + r+ + + + + +Lg +yl+ g+ e+Al+++++a++ FUN_001585-T2 601 LLISCFVDNGQTGRARDLLPELFAERDRSSKEFS--YGDSCVLLGYCYLRFGEKEQALSMFKEAVD 664 6666777777777777777777777777755555..7888889********************975 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 5.1 9.4e+03 2 11 .. 406 415 .. 405 419 .. 0.86 2 ? 0.8 0.0 0.8 1.5e+03 9 26 .. 535 552 .. 529 555 .. 0.81 3 ? -0.3 0.0 1.7 3.1e+03 3 23 .. 599 619 .. 598 622 .. 0.91 4 ! 12.8 0.0 0.00012 0.21 5 30 .. 641 666 .. 640 668 .. 0.92 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 5.1 TPR_6 2 Allklalsyl 11 All ++ +y FUN_001585-T2 406 ALLEIGFCYA 415 9*******96 PP == domain 2 score: 0.8 bits; conditional E-value: 0.8 TPR_6 9 sylelgdkdeAkaalqrl 26 ++e+ + +eA+++l + FUN_001585-T2 535 FLYEQRRLEEAISILTTI 552 578888*******99866 PP == domain 3 score: -0.3 bits; conditional E-value: 1.7 TPR_6 3 llklalsylelgdkdeAkaal 23 l+ l ++ g++ +A+++l FUN_001585-T2 599 LYLLISCFVDNGQTGRARDLL 619 899999****99*****9986 PP == domain 4 score: 12.8 bits; conditional E-value: 0.00012 TPR_6 5 klalsylelgdkdeAkaalqrlikkY 30 l+++yl+ g+k++A++++++ ++++ FUN_001585-T2 641 LLGYCYLRFGEKEQALSMFKEAVDEH 666 59******99***********99987 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.28 5.1e+02 6 24 .. 533 551 .. 530 556 .. 0.85 2 ! 12.7 0.0 8.1e-05 0.15 1 32 [. 638 667 .. 638 671 .. 0.86 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.28 TPR_7 6 ariyrklGdydeAirlyer 24 a+++ +++ +eAi++++ FUN_001585-T2 533 ANFLYEQRRLEEAISILTT 551 5677788********9986 PP == domain 2 score: 12.7 bits; conditional E-value: 8.1e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdp 32 ++++L+ +y + G+ ++A++++++ a++++ FUN_001585-T2 638 SCVLLGYCYLRFGEKEQALSMFKE--AVDEHA 667 699*********************..666554 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.64 1.2e+03 6 24 .. 531 549 .. 528 552 .. 0.88 2 ? 0.2 0.0 1.4 2.6e+03 4 24 .. 599 619 .. 598 628 .. 0.88 3 ! 10.6 0.0 0.00063 1.2 6 38 .. 641 674 .. 639 678 .. 0.85 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.64 TPR_14 6 alarallalGdpdeAlell 24 + a++l ++ +++eA+ +l FUN_001585-T2 531 LFANFLYEQRRLEEAISIL 549 67999***********987 PP == domain 2 score: 0.2 bits; conditional E-value: 1.4 TPR_14 4 wlalarallalGdpdeAlell 24 +++l+ ++ +G++ +A++ll FUN_001585-T2 599 LYLLISCFVDNGQTGRARDLL 619 578889999*********997 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00063 TPR_14 6 alarallalGdpdeAlelleralaldPddp.eaw 38 +l++ +l+ G+ ++Al ++++a+ + +d+ +w FUN_001585-T2 641 LLGYCYLRFGEKEQALSMFKEAVDEHASDAgKYW 674 68999********************998862555 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.2 2.1e+03 6 24 .. 531 549 .. 527 552 .. 0.82 2 ! 13.9 0.0 3.7e-05 0.067 2 29 .. 637 664 .. 636 665 .. 0.94 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.2 TPR_8 6 nlGliylklgdyeeAkeyy 24 + ++ + ++ ++eeA+ ++ FUN_001585-T2 531 LFANFLYEQRRLEEAISIL 549 5678889999*****9876 PP == domain 2 score: 13.9 bits; conditional E-value: 3.7e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekale 29 +++++lG++yl+ g++e+A +++a++ FUN_001585-T2 637 DSCVLLGYCYLRFGEKEQALSMFKEAVD 664 689***********************85 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 5.3 9.7e+03 3 17 .. 406 420 .. 405 420 .. 0.85 2 ? 1.5 0.0 0.34 6.2e+02 8 22 .. 533 547 .. 532 551 .. 0.86 3 ? 10.2 0.0 0.00052 0.95 4 29 .. 639 664 .. 636 666 .. 0.90 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 5.3 TPR_2 3 alynlGlayyklgdy 17 al + G +y+ g++ FUN_001585-T2 406 ALLEIGFCYAVEGKF 420 78899****999986 PP == domain 2 score: 1.5 bits; conditional E-value: 0.34 TPR_2 8 GlayyklgdyeeAle 22 ++ +y++ ++eeA+ FUN_001585-T2 533 ANFLYEQRRLEEAIS 547 6779*********95 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00052 TPR_2 4 lynlGlayyklgdyeeAleayekAle 29 + lG++y++ g+ e+Al +++A+ FUN_001585-T2 639 CVLLGYCYLRFGEKEQALSMFKEAVD 664 678*********************85 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 1.1 2e+03 3 17 .. 406 420 .. 404 420 .. 0.88 2 ? -0.3 0.0 0.86 1.6e+03 8 21 .. 533 546 .. 533 547 .. 0.88 3 ? 10.7 0.0 0.00029 0.53 5 28 .. 640 663 .. 637 666 .. 0.90 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.1 TPR_1 3 alynlGnayfklgky 17 al +G +y gk+ FUN_001585-T2 406 ALLEIGFCYAVEGKF 420 8999******99997 PP == domain 2 score: -0.3 bits; conditional E-value: 0.86 TPR_1 8 GnayfklgkydeAl 21 +n ++++ +++eA+ FUN_001585-T2 533 ANFLYEQRRLEEAI 546 57799********9 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00029 TPR_1 5 ynlGnayfklgkydeAleyyekAL 28 lG++y++ g+ ++Al +++A+ FUN_001585-T2 640 VLLGYCYLRFGEKEQALSMFKEAV 663 579*******************97 PP >> TPR_NUP160_120_M NUP160/120 middle TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.5 4.5e+03 32 62 .. 590 620 .. 571 632 .. 0.79 2 ? 12.1 0.0 7e-05 0.13 40 71 .. 638 669 .. 628 684 .] 0.78 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.5 TPR_NUP160_120_M 32 wcewnsasrkfllavslLelgeaekaldlfl 62 + w + +ll ++++++g++ +a dl+ FUN_001585-T2 590 VEYWVPTFTLYLLISCFVDNGQTGRARDLLP 620 5567777788999999999999999998865 PP == domain 2 score: 12.1 bits; conditional E-value: 7e-05 TPR_NUP160_120_M 40 rkfllavslLelgeaekaldlfleaakgvlke 71 ll+ ++L++ge+e+al++f+ea+++ +++ FUN_001585-T2 638 SCVLLGYCYLRFGEKEQALSMFKEAVDEHASD 669 5689**********************999887 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 9.4 1.7e+04 6 23 .. 376 393 .. 375 410 .. 0.62 2 ? 1.6 0.0 0.3 5.5e+02 38 52 .. 533 547 .. 517 554 .. 0.82 3 ? 9.2 0.0 0.0013 2.4 8 64 .. 607 669 .. 600 670 .. 0.71 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 9.4 TPR_16 6 aalaagdyddAaaaleaa 23 a+ + ++y++ +++ ++ FUN_001585-T2 376 ALKDTNRYARGIRLVARH 393 566778888888766554 PP == domain 2 score: 1.6 bits; conditional E-value: 0.3 TPR_16 38 GlallrqgrlaeAaa 52 + l++q+rl+eA+ FUN_001585-T2 533 ANFLYEQRRLEEAIS 547 778999999999985 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0013 TPR_16 8 laagdyddAaaaleaalrrn.PeaaaAllg.....lGlallrqgrlaeAaaayraalraapgd 64 +++g+ +A+ +l ++ + + ++ ++++g lG+++lr g+ + A+ +++a+++ ++d FUN_001585-T2 607 VDNGQTGRARDLLPELFAERdRSSKEFSYGdscvlLGYCYLRFGEKEQALSMFKEAVDEHASD 669 66777777777774444444455555555333333**********************998887 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 5.6 1e+04 14 23 .. 540 549 .. 537 553 .. 0.84 2 ? 4.1 0.0 0.052 95 5 23 .. 601 619 .. 597 624 .. 0.87 3 ? 4.6 0.2 0.034 62 9 26 .. 645 662 .. 639 666 .. 0.89 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 5.6 PPR 14 GkleeAlelf 23 ++leeA++++ FUN_001585-T2 540 RRLEEAISIL 549 689****987 PP == domain 2 score: 4.1 bits; conditional E-value: 0.052 PPR 5 slIsgycknGkleeAlelf 23 lIs+++ nG+ A +l+ FUN_001585-T2 601 LLISCFVDNGQTGRARDLL 619 69*************9998 PP == domain 3 score: 4.6 bits; conditional E-value: 0.034 PPR 9 gycknGkleeAlelfkeM 26 +y + G+ e Al++fke FUN_001585-T2 645 CYLRFGEKEQALSMFKEA 662 899*************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (684 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 478 (0.0187121); expected 510.9 (0.02) Passed bias filter: 433 (0.0169505); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.37u 0.36s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 6617.70 // Query: FUN_001587-T1 [L=894] Description: FUN_001587 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-24 85.5 0.1 6.5e-24 84.2 0.1 1.7 1 Bromodomain Bromodomain ------ inclusion threshold ------ 7.6 5.1 10.9 12 4.5 10.9 1.3 1 CDC45 CDC45 Domain annotation for each model (and alignments): >> Bromodomain Bromodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.2 0.1 5.1e-28 6.5e-24 5 84 .] 779 858 .. 775 858 .. 0.95 Alignments for each domain: == domain 1 score: 84.2 bits; conditional E-value: 5.1e-28 Bromodomain 5 ldkllehdiakpFlepvdpeeypdYysvikkPidLstIkkklenneYkslaefeadvklifsNaitynkegsvvykaaek 84 ++ +h+ a+ Fl+pv+++e+p Y+sv+ +P+dLstIkk++en+++++ +ef++d+ l+f+Na +yn +++vy++ae+ FUN_001587-T1 779 WRAAANHKYANVFLHPVTDDEAPGYHSVVFRPMDLSTIKKNIENGTIRTTSEFQRDMMLMFQNALMYNSADHDVYRMAEE 858 666789999********************************************************************985 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 10.9 0.00097 12 119 196 .. 656 755 .. 640 866 .. 0.51 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.00097 CDC45 119 keayealeeeeeedeedeeeeeeddeeeeeeeeeeedeeeeeedeeeskkkrksesdeeeeeeddeeersrkrrrse................... 195 + e+ eee++ ++ d e+e+ d+e+eee ++ +ed+++++e+e e+++ +++ sd e+++++++e+ e FUN_001587-T1 656 GDTEEDHEEEPKFEHVDVESEKADEEDEEEIDSTAEDKKDYSEEEIERESGEEAVSDFGERSQSEKDEQ-------Epgtsmkeflldragiggte 744 222222222222222222333333333333333333333333333333333333333333322222222.......12333333555556666666 PP CDC45 196 ..........e 196 + FUN_001587-T1 745 svpgspasqvS 755 66655555550 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (894 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1627 (0.0636915); expected 510.9 (0.02) Passed bias filter: 626 (0.0245058); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.44s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 8640.09 // Query: FUN_001587-T2 [L=808] Description: FUN_001587 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 12.8 0.1 0.32 11.5 0.0 1.7 2 Bromodomain Bromodomain Domain annotation for each model (and alignments): >> Bromodomain Bromodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.0 0.0 0.85 2.2e+04 7 27 .. 65 85 .. 63 87 .. 0.75 2 ? 11.5 0.0 1.3e-05 0.32 5 33 .. 778 806 .. 774 808 .] 0.89 Alignments for each domain: == domain 1 score: -4.0 bits; conditional E-value: 0.85 Bromodomain 7 kllehdiakpFlepvdpeeyp 27 ++++++a +++e++++++ p FUN_001587-T2 65 FFSQKNCASHYSEMLEKVNTP 85 567778899999888877776 PP == domain 2 score: 11.5 bits; conditional E-value: 1.3e-05 Bromodomain 5 ldkllehdiakpFlepvdpeeypdYysvi 33 ++ +h+ a+ Fl+pv+++e+p Y+sv+ FUN_001587-T2 778 WRAAANHKYANVFLHPVTDDEAPGYHSVV 806 666789999******************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (808 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1825 (0.0714426); expected 510.9 (0.02) Passed bias filter: 725 (0.0283813); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.44u 0.43s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 7559.72 // Query: FUN_001588-T1 [L=185] Description: FUN_001588 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 4.4 7.5 7.3 5 7.3 7.3 1.2 1 RR_TM4-6 Ryanodine Receptor TM 4-6 Domain annotation for each model (and alignments): >> RR_TM4-6 Ryanodine Receptor TM 4-6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 7.3 0.0002 5 71 150 .. 87 167 .. 23 181 .. 0.65 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0002 RR_TM4-6 71 gdlsettaeetppelkkklqeeeeaedekeeeeepkaeeekadsedgekeekeke.eeeeeeeeeeekkkkkkrkskkkee 150 d s+ +++ p ++++ +++++++ + +++e ++ +++++d+++ +k+eke+e ++++++++ ++++ ++r+++ +e FUN_001588-T1 87 DDYSSRRSRSRSPRRRRRRSHSKSKSRSPRRRERTSRSDRNRDNHRDSKREKERErSQSRSPSRARSRSASRSRSASPVAE 167 566777777777777777777777777777777777777777777777777666623333334444444444433333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1758 (0.0688197); expected 510.9 (0.02) Passed bias filter: 487 (0.0190644); expected 510.9 (0.02) Passed Vit filter: 114 (0.00446271); expected 25.5 (0.001) Passed Fwd filter: 32 (0.00125269); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.39 # Mc/sec: 1891.36 // Query: FUN_001589-T1 [L=61] Description: FUN_001589 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-14 54.0 0.0 1.9e-14 53.8 0.0 1.0 1 RRM_1 RNA recognition motif Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.8 0.0 7.4e-19 1.9e-14 1 46 [. 12 58 .. 12 59 .. 0.98 Alignments for each domain: == domain 1 score: 53.8 bits; conditional E-value: 7.4e-19 RRM_1 1 lfVgnLppdvteeeLkelFskfGpiksirlvrd.etgrskgfafVeF 46 l+V+nL++d+ e+L+++F+k+G+i+++ ++ d t+ s+gfa+V++ FUN_001589-T1 12 LYVRNLHHDTRPEDLRRMFGKYGRITDVYIPLDyYTRESRGFAYVQY 58 8*********************************************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (61 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 368 (0.014406); expected 510.9 (0.02) Passed bias filter: 341 (0.013349); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 631.76 // Query: FUN_001590-T1 [L=320] Description: FUN_001590 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-29 101.8 2.3 2.1e-29 101.8 2.3 2.2 3 SLBP_RNA_bind Histone RNA hairpin-binding protein RNA-bindin Domain annotation for each model (and alignments): >> SLBP_RNA_bind Histone RNA hairpin-binding protein RNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 0.41 1e+04 32 42 .. 35 45 .. 26 52 .. 0.68 2 ? -3.3 0.1 0.55 1.4e+04 39 55 .. 155 171 .. 143 174 .. 0.56 3 ! 101.8 2.3 8.3e-34 2.1e-29 2 70 .] 184 251 .. 183 251 .. 0.98 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 0.41 SLBP_RNA_bind 32 ekrkkkehPkT 42 ++r++k++P+T FUN_001590-T1 35 SSRRPKKNPRT 45 45565777777 PP == domain 2 score: -3.3 bits; conditional E-value: 0.55 SLBP_RNA_bind 39 hPkTPdknqkvSkrswd 55 + + P+ ++k+ ++++ FUN_001590-T1 155 EMTNPRSKRKLQLSEFQ 171 44556666665555555 PP == domain 3 score: 101.8 bits; conditional E-value: 8.3e-34 SLBP_RNA_bind 2 deerlkqRqKqIdyGKntigYqrYlkaVpkekrkkkehPkTPdknqkvSkrswdgqikkWrraLhefdp 70 de+rl++RqKqId+GKnt +Y rY++aV++e+r+ ke+P+TPdk+q +S rsw gqik Wrr+Lh +dp FUN_001590-T1 184 DEHRLQKRQKQIDFGKNTLAYGRYIDAVKREDRT-KEDPNTPDKFQACSTRSWVGQIKIWRRKLHVWDP 251 79********************************.8********************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (320 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1169 (0.0457624); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.34s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 3215.75 // Query: FUN_001591-T1 [L=400] Description: FUN_001591 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-13 51.1 7.3 1.7e-13 51.1 7.3 2.2 1 zf-RING_2 Ring finger domain 2.1e-09 37.9 4.0 2.1e-09 37.9 4.0 3.0 1 zf-rbx1 RING-H2 zinc finger domain 2.8e-08 33.8 3.4 2.8e-08 33.8 3.4 3.0 2 zf-RING_11 RING-like zinc finger 6.5e-08 32.8 5.4 1.6e-07 31.5 5.4 1.7 1 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 1.4e-07 31.7 5.8 4.5e-07 30.0 5.8 2.0 1 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 1.8e-05 24.9 5.1 3.5e-05 24.0 5.1 1.5 1 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 2.5e-05 24.7 4.1 5e-05 23.7 4.1 1.6 1 zf-RING_5 zinc-RING finger domain 7.2e-05 23.2 2.0 8.6e-05 22.9 0.8 1.8 1 zf-RING_UBOX RING-type zinc-finger 0.00011 22.6 1.8 0.00011 22.6 1.8 2.8 2 zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H ------ inclusion threshold ------ 0.011 15.8 3.7 0.029 14.5 3.7 1.7 1 zf-RING_16 RING/Ubox like zinc-binding domain 0.083 13.5 0.6 0.16 12.6 0.6 1.5 1 VPS18_RING_C VPS18 RING C-terminal domain 0.31 11.5 8.8 0.44 11.0 6.0 2.4 2 Prok-RING_4 Prokaryotic RING finger family 4 0.46 11.2 4.9 1.2 9.9 4.9 1.7 1 RINGv RING-variant domain 1 10.2 4.4 6.3 7.7 4.4 2.2 1 FANCL_C FANCL C-terminal domain 1.2 9.7 9.8 7.1 7.3 5.9 3.3 2 RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING Domain annotation for each model (and alignments): >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.1 7.3 9.9e-17 1.7e-13 2 44 .] 350 392 .. 349 392 .. 0.97 Alignments for each domain: == domain 1 score: 51.1 bits; conditional E-value: 9.9e-17 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsstCPlCr 44 C++Cl ++ee++ v+vlpC H +h C+dkwl++++tCP+Cr FUN_001591-T1 350 RCVVCLVDFEEKQLVRVLPCLHEYHTRCIDKWLKSNRTCPICR 392 7*****************************************9 PP >> zf-rbx1 RING-H2 zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 4.0 1.3e-12 2.1e-09 13 55 .] 350 392 .. 344 392 .. 0.80 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 1.3e-12 zf-rbx1 13 acieckapgdeecpvvwGeCgHaFHlhCiskWlktrntCPlcr 55 c+ c + +e+ v + C H++H+ Ci+kWlk+++tCP+cr FUN_001591-T1 350 RCVVCLVDFEEKQLVRVLPCLHEYHTRCIDKWLKSNRTCPICR 392 5777776666653444448***********************8 PP >> zf-RING_11 RING-like zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.8 3.4 1.6e-11 2.8e-08 2 29 .] 351 378 .. 351 378 .. 0.99 2 ? -1.0 0.1 1.3 2.2e+03 2 9 .. 388 395 .. 388 398 .. 0.81 Alignments for each domain: == domain 1 score: 33.8 bits; conditional E-value: 1.6e-11 zf-RING_11 2 CsICleefkpgqalfvlpCsHvFHykCi 29 C++Cl +f+++q ++vlpC H +H +Ci FUN_001591-T1 351 CVVCLVDFEEKQLVRVLPCLHEYHTRCI 378 ***************************9 PP == domain 2 score: -1.0 bits; conditional E-value: 1.3 zf-RING_11 2 CsICleef 9 C IC e+ FUN_001591-T1 388 CPICRAEV 395 ****8776 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.5 5.4 9.6e-11 1.6e-07 1 40 [] 351 391 .. 351 391 .. 0.92 Alignments for each domain: == domain 1 score: 31.5 bits; conditional E-value: 9.6e-11 zf-C3HC4 1 CpiCleelkepv..tllpCgHsfCssCiksllesnnvkCplC 40 C +Cl ++e+ ++lpC+H++++ Ci+++l+ +n++Cp C FUN_001591-T1 351 CVVCLVDFEEKQlvRVLPCLHEYHTRCIDKWLK-SNRTCPIC 391 899999998887779******************.8899**** PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.0 5.8 2.6e-10 4.5e-07 1 40 [] 350 391 .. 350 391 .. 0.86 Alignments for each domain: == domain 1 score: 30.0 bits; conditional E-value: 2.6e-10 zf-C3HC4_2 1 eCpiCldmlkdp..lvvtpCgHvfCqkCilraLeesneCPlC 40 +C +Cl +++ ++v pC H ++ Ci+++L+++ CP+C FUN_001591-T1 350 RCVVCLVDFEEKqlVRVLPCLHEYHTRCIDKWLKSNRTCPIC 391 69***9988876224556************************ PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 5.1 2e-08 3.5e-05 2 46 .. 348 395 .. 347 397 .. 0.86 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 2e-08 zf-C3HC4_3 2 eeeCviCler...ernvvllpCgHlclCeeCaeklr.kkkkCpiCrqki 46 ++ Cv+Cl ++ v +lpC H + C +k+ ++++CpiCr+++ FUN_001591-T1 348 NNRCVVCLVDfeeKQLVRVLPCLHE-YHTRCIDKWLkSNRTCPICRAEV 395 789****86433267799*******.99******************998 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 4.1 3e-08 5e-05 1 42 [. 350 392 .. 350 393 .. 0.95 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 3e-08 zf-RING_5 1 hCnkCfkelsktrkfyltsCgHifCeeClkkll.eerqCpiCk 42 +C +C ++++++ + +++C H ++ +C++k l ++r+CpiC+ FUN_001591-T1 350 RCVVCLVDFEEKQLVRVLPCLHEYHTRCIDKWLkSNRTCPICR 392 6********99999*****************999********8 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.8 5.1e-08 8.6e-05 1 39 [] 351 389 .. 351 389 .. 0.87 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 5.1e-08 zf-RING_UBOX 1 CpICleeftdP..lv.lpCGHtfCreClwelskkekgkikCP 39 C +Cl +f++ ++ lpC H ++ C+ +k+ k++ +CP FUN_001591-T1 351 CVVCLVDFEEKqlVRvLPCLHEYHTRCI---DKWLKSNRTCP 389 99*******55553436***********...999*******9 PP >> zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.7 6.6 1.1e+04 52 60 .. 88 96 .. 67 106 .. 0.64 2 ! 22.6 1.8 6.7e-08 0.00011 15 63 .. 351 397 .. 344 399 .. 0.81 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 6.6 zf-ANAPC11 52 glcPmcrqt 60 cP +q FUN_001591-T1 88 HGCPFLQQR 96 445554443 PP == domain 2 score: 22.6 bits; conditional E-value: 6.7e-08 zf-ANAPC11 15 cPeckvPGddcplvlGk.ckhsfhlhcilkWletetskglcPmcrqtfkl 63 c c v ++ lv c h +h+ ci kWl+ s+ cP+cr ++++ FUN_001591-T1 351 CVVCLVDFEEKQLVRVLpCLHEYHTRCIDKWLK---SNRTCPICRAEVNV 397 777777777777876666**************7...5679*****98776 PP >> zf-RING_16 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 3.7 1.7e-05 0.029 4 46 .. 348 389 .. 345 397 .. 0.84 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.7e-05 zf-RING_16 4 lkkCayCelavk.grlflcgvCeHvlHasCareWfenddlaeCp 46 ++ C++C + + ++l+ C H H+ C +W + + +Cp FUN_001591-T1 348 NNRCVVCLVDFEeKQLVRVLPCLHEYHTRCIDKWLKSNR--TCP 389 678******997256777889*************99988..787 PP >> VPS18_RING_C VPS18 RING C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.6 9.5e-05 0.16 5 35 .. 349 380 .. 345 391 .. 0.88 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 9.5e-05 VPS18_RING_C 5 ekcyvctlpllsrqff.vfpcqhafhsdclgk 35 ++c+vc + + +q+ v+pc h +h+ c+ k FUN_001591-T1 349 NRCVVCLVDFEEKQLVrVLPCLHEYHTRCIDK 380 79************8659***********987 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.6 1e+03 30 39 .. 86 96 .. 81 102 .. 0.71 2 ? 11.0 6.0 0.00026 0.44 1 41 [. 351 396 .. 351 399 .. 0.74 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.6 Prok-RING_4 30 fs.aCPiCrrr 39 ++ +CP+ ++r FUN_001591-T1 86 SNhGCPFLQQR 96 4449***9888 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00026 Prok-RING_4 1 Cvlcgre...etkivlspCgHlvCkeCfdss.dfs.aCPiCrrrvd 41 Cv+c ++ + pC H C d+ +++ CPiCr +v+ FUN_001591-T1 351 CVVCLVDfeeKQLVRVLPCLHEYHTRCIDKWlKSNrTCPICRAEVN 396 78887554326666799*****999999985233469*****9986 PP >> RINGv RING-variant domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 4.9 0.00068 1.2 1 47 [] 351 391 .. 351 391 .. 0.77 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00068 RINGv 1 CriCleeeeeseplispCkCrGslklvHksClekWlsekantqCeiC 47 C +Cl + ee++ l++ C l+ H C++kWl++ n++C iC FUN_001591-T1 351 CVVCLVDFEEKQ-LVRVLPC---LHEYHTRCIDKWLKS--NRTCPIC 391 788888877766.6665555...6789*********75..7789999 PP >> FANCL_C FANCL C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 4.4 0.0037 6.3 26 45 .. 368 387 .. 348 399 .. 0.84 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0037 FANCL_C 26 kCakkfHrvCLeeWlrslsk 45 C +++H+ C+ Wl+s+++ FUN_001591-T1 368 PCLHEYHTRCIDKWLKSNRT 387 599**************986 PP >> RING_XB3-XBAT31 E3 ubiquitin-protein ligase XB3/XBAT31 RING finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 0.95 1.6e+03 34 50 .. 76 92 .. 65 99 .. 0.71 2 ? 7.3 5.9 0.0042 7.1 1 55 [. 353 395 .. 350 397 .. 0.77 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.95 RING_XB3-XBAT31 34 kkteaataskespaCPf 50 +++ +++ s+++ CPf FUN_001591-T1 76 SNPPESHGSPSNHGCPF 92 45566677788889**9 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0042 RING_XB3-XBAT31 1 lCsiCferactieveeCgHqlCaqCalalcskkkkteaataskespaCPfCRssi 55 +C + fe+ + v +C H+ ++C+ + +++ +CP+CR ++ FUN_001591-T1 353 VCLVDFEEKQLVRVLPCLHEYHTRCIDKWLKSN------------RTCPICRAEV 395 355558999****************97655543............3699999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (400 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 982 (0.038442); expected 510.9 (0.02) Passed bias filter: 482 (0.0188687); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3850.88 // Query: FUN_001592-T1 [L=510] Description: FUN_001592 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-11 43.1 1.4 1.6e-10 41.4 1.4 2.0 1 Myb_DNA-binding Myb-like DNA-binding domain 3.8e-07 30.7 0.6 1.8e-06 28.5 0.6 2.3 1 Myb_DNA-bind_6 Myb-like DNA-binding domain ------ inclusion threshold ------ 0.048 15.1 0.2 0.048 15.1 0.2 2.7 3 DncV-like_NTFase Cyclic GMP-AMP synthase DncV-like, nucleoti Domain annotation for each model (and alignments): >> Myb_DNA-binding Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.4 1.4 1.9e-14 1.6e-10 4 45 .. 462 506 .. 459 507 .. 0.96 Alignments for each domain: == domain 1 score: 41.4 bits; conditional E-value: 1.9e-14 Myb_DNA-binding 4 WtpeEdelLleaveklG.nrWkkIakllp..gRtdkqcknrwqny 45 Wt+eE + L e+v+ +G ++W kI + ++ gRt ++ k+rw+++ FUN_001592-T1 462 WTAEETKWLEEGVKAYGeGNWTKILNAYNfvGRTSVNLKDRWRTL 506 *******************************************86 PP >> Myb_DNA-bind_6 Myb-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.6 2.1e-10 1.8e-06 1 44 [. 462 508 .. 462 510 .] 0.84 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 2.1e-10 Myb_DNA-bind_6 1 WteeEdekLiqlvekygn.dWkqI..akelg..rRtpkqcrerwkrklk 44 Wt+eE++ L + v++yg +W +I a ++ Rt+ ++++rw++ +k FUN_001592-T1 462 WTAEETKWLEEGVKAYGEgNWTKIlnA--YNfvGRTSVNLKDRWRTLHK 508 ****************955*****555..55555***********9444 PP >> DncV-like_NTFase Cyclic GMP-AMP synthase DncV-like, nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.2 5.7e-06 0.048 26 77 .. 18 68 .. 13 75 .. 0.90 2 ? -1.8 0.2 1 8.9e+03 47 71 .. 276 300 .. 261 310 .. 0.46 3 ? -1.7 0.0 0.98 8.3e+03 50 78 .. 423 453 .. 408 458 .. 0.65 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 5.7e-06 DncV-like_NTFase 26 iDdGvYleveklekepelaakalkelveealkelaekkkkeleekktCvRve 77 +D+ vYl +++++++ + +a + ++v++ l++++ + ++el++k +C+R FUN_001592-T1 18 LDYCVYLLWKEFKQKRAFSACW-SDTVQDYLENKQYHVEQELTHKVQCIRFL 68 79**********9999998777.679********999*************75 PP == domain 2 score: -1.8 bits; conditional E-value: 1 DncV-like_NTFase 47 alkelveealkelaekkkkeleekk 71 + ++++++++++++++++ ++k+ FUN_001592-T1 276 THNHITDKTIRQVVQSNGAASNSKR 300 2233333333333333333333333 PP == domain 3 score: -1.7 bits; conditional E-value: 0.98 DncV-like_NTFase 50 elveealkelaekkkkel.e.ekktCvRvey 78 e+ve+ ++ e+k+ +l + k++C v++ FUN_001592-T1 423 EIVEWESDDEIETKTIKLpSpLKRRCLNVKL 453 5666666666655554543358999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (510 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1764 (0.0690546); expected 510.9 (0.02) Passed bias filter: 775 (0.0303386); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.41s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 4955.37 // Query: FUN_001593-T1 [L=1218] Description: FUN_001593 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-64 216.2 0.0 3.6e-63 213.9 0.0 2.4 1 Pkinase Protein kinase domain 2.9e-54 183.4 80.0 9.1e-30 104.1 32.1 8.3 9 PKK Polo kinase kinase 8e-46 156.9 0.0 8e-46 156.9 0.0 2.1 2 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.2e-09 38.2 0.5 7.9e-08 32.2 0.1 2.8 2 ABC1 ABC1 atypical kinase-like domain Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 213.9 0.0 5.6e-67 3.6e-63 3 262 .] 35 291 .. 33 291 .. 0.93 Alignments for each domain: == domain 1 score: 213.9 bits; conditional E-value: 5.6e-67 Pkinase 3 vleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkga.lse 97 + +lG+GsfgkV ka +k++g + A K+i+ +++++ ++ ++ Ei+il+++kh+++v ++++++++++l+++lE+++gg l+dl+ + l+e FUN_001593-T1 35 LVGELGDGSFGKVHKAERKTDGTLAAAKIIDVKDESELDD--FMVEIDILSECKHSHVVGMYEAYYHENKLWMMLEFCSGGALDDLILEIERgLTE 128 5679*****************************9998776..********************************************9865555*** PP Pkinase 98 eeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk.ltsfvgtseYmAPEvl.....kskkygkkvDvWslGvil 187 +++k +++q++e l++lH ++v+HrDlK N+L++++g++K++DFG++++ +++ + t+f+gt+++mAPEv+ k+ +y+ k+D+Ws+G++l FUN_001593-T1 129 DQIKVVCRQMFECLHFLHTHKVIHRDLKAGNLLLTSDGNIKLADFGVSAKNKKTVQrRTTFIGTPYWMAPEVIvtetcKDDPYDYKADIWSAGITL 224 **************************************************99999989******************9999**************** PP Pkinase 188 yelltgkppfsaekekekvekeldqlekilki..elkeklpepssiseeakdllkkllkkdpkkRltaeellqhpwf 262 +el +pp++ +++ + ++ki +l+ +++ s+++ d+l+ ++ k + R +a +ll+hp++ FUN_001593-T1 225 IELAEMQPPYH----------DMHPMRVLFKIpkSDPPQLQAKNKWSKHFHDFLSLCVVKSADMRTSAGQLLEHPFI 291 ***********..........5555556666643335678889999*****************************97 PP >> PKK Polo kinase kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -10.0 14.9 4 2.6e+04 68 125 .. 327 388 .. 318 399 .. 0.59 2 ? -36.5 60.5 4 2.6e+04 19 107 .. 366 467 .. 353 509 .. 0.46 3 ? -4.6 6.4 4 2.6e+04 76 105 .. 569 593 .. 543 636 .. 0.56 4 ? -4.4 4.9 4 2.6e+04 76 111 .. 672 701 .. 637 719 .. 0.52 5 ? -1.9 2.3 0.74 4.7e+03 42 61 .. 798 817 .. 752 822 .. 0.62 6 ! 104.1 32.1 1.4e-33 9.1e-30 3 139 .] 828 964 .. 826 964 .. 0.98 7 ? -4.0 0.5 3.4 2.2e+04 11 32 .. 966 987 .. 965 992 .. 0.67 8 ! 94.7 39.8 1.1e-30 7e-27 1 139 [] 994 1134 .. 994 1134 .. 0.97 9 ? -4.1 2.7 3.5 2.2e+04 95 110 .. 1159 1175 .. 1136 1193 .. 0.45 Alignments for each domain: == domain 1 score: -10.0 bits; conditional E-value: 4 PKK 68 kesLKqekke....lkqev..eklpkfqrkeklrqkkeeleleqkeeekeflqkqkealekelk 125 k++LK++ + + + +r e + ++e++e ++ +e ++++ + e++e+e + FUN_001593-T1 327 KNELKISESTdsldES--AewNNEIETDRDEGEKEEEENKETDKDHENEKEMGGKDEEAEEEKE 388 5666666655442222..2335555566777777777777777777766666666666666544 PP == domain 2 score: -36.5 bits; conditional E-value: 4 PKK 19 lkkryekEleqlerqqkqqiEkleqeqeqelrelpKriRaEqekelkk............FkesLKqekkelkqev.eklpkfqrkeklrqkkeel 101 k +e+E e + ++ ++Ek e ++e ++ + + +E ++ ++ ke L + + +qe+ e+ +++++ke r++++e+ FUN_001593-T1 366 TDKDHENEKEMGGKDEEAEEEKETVETKVEEEKSEREQAEERKENDQMkeeevkdeetveNKEDLGDKREAESQEKvEEAKEEEEKEDERTESKEK 461 445555555555555555555555555555555555555555555555000000000000555555444444444445555555555555444443 PP PKK 102 eleqke 107 +e+ FUN_001593-T1 462 GEEEVA 467 333333 PP == domain 3 score: -4.6 bits; conditional E-value: 4 PKK 76 kelkqeveklpkfqrkeklrqkkeeleleq 105 +e k+e++k ++++ +e+ + + +e+ FUN_001593-T1 569 TEEKEEQDKRKEDEASETVKSE-----VEN 593 2222222222222222222222.....222 PP == domain 4 score: -4.4 bits; conditional E-value: 4 PKK 76 kelkqev..eklpkfqrkeklrqkkeeleleqkeeeke 111 e+++e ek+ +++ +e+ + + + +e FUN_001593-T1 672 DESDKEIggEKIEQEKDEEAVKDSAVD--------NQE 701 222222233333333333333333333........333 PP == domain 5 score: -1.9 bits; conditional E-value: 0.74 PKK 42 eqeqeqelrelpKriRaEqe 61 +q+ +++lrel +R+Eq+ FUN_001593-T1 798 QQQRKVNLRELKILQREEQK 817 23333344444444444444 PP == domain 6 score: 104.1 bits; conditional E-value: 1.4e-33 PKK 3 lqkeqlkrrfeqertqlkkryekEleqlerqqkqqiEkleqeqeqelrelpKriRaEqekelkkFkesLKqekkelkqeveklpkfqrkeklrqkk 98 q+e +++rfeqe + l k+ye +l++l+r+qk++iEkle +q+ +lr+++++++++qekelk F+++L++e k+ k+ev+ lp++ rke++r+k+ FUN_001593-T1 828 RQWEAQEQRFEQELQDLDKKYEVDLDNLSRNQKKEIEKLEVSQNSDLRTSSRKMKQDQEKELKRFRDNLREEHKSAKKEVDGLPRNLRKETWRKKR 923 6899******************************************************************************************** PP PKK 99 eeleleqkeeekeflqkqkealekelkqlqnekrkelaetE 139 ee e++q++ e+efl+ q+ + ek +k+l++ +r++++++E FUN_001593-T1 924 EEIEVSQRQAEHEFLAMQQVNFEKFCKELIELHRERMYNLE 964 *************************************9987 PP == domain 7 score: -4.0 bits; conditional E-value: 3.4 PKK 11 rfeqertqlkkryekEleqler 32 +f q ++ lk+ +e E ++e FUN_001593-T1 966 QFLQNKHGLKRGHEGERWEIEQ 987 6778888888888877544444 PP == domain 8 score: 94.7 bits; conditional E-value: 1.1e-30 PKK 1 lqlqkeqlkrrfeqertqlkkryekEleqlerqqkqqiEkleqeqeqelrelpKriRaEqekelkkFkesLKqekke.lkqeveklpkfqrkek 93 +ql++ qlk+ f+++r+q+++r++kE eq++r k ++E++++++e+e+++lpK++R E +++++++++s++++k+ ++ e e++++f+ e+ FUN_001593-T1 994 HQLARTQLKETFFLQRSQMLNRHQKECEQHSRLTKLKEEEMKRRHEIERKRLPKIQRDEIKAKSHQYRKSIRIDKRMsIDVEREMMKEFESVER 1087 89*************************************************************************97566666*********** PP PKK 94 lrqkkeeleleqkee.ekeflqkqkealekelkqlqnekrkelaetE 139 +r++ e +++ ++e e e+l+ +e++ kel+qlqnekr++l+e E FUN_001593-T1 1088 KRARTEYEKMLFRQEmEAEELRVSSESALKELQQLQNEKRHMLMESE 1134 *********************************************98 PP == domain 9 score: -4.1 bits; conditional E-value: 3.5 PKK 95 rqkkeeleleqkee.ek 110 r+k+ e+e+ +e+ ++ FUN_001593-T1 1159 RKKAVEEEFAREEReQQ 1175 33333333333333222 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 156.9 0.0 1.2e-49 8e-46 5 256 .. 37 287 .. 34 288 .. 0.93 2 ? -5.2 1.1 3.6 2.3e+04 29 60 .. 1112 1143 .. 1101 1150 .. 0.65 Alignments for each domain: == domain 1 score: 156.9 bits; conditional E-value: 1.2e-49 PK_Tyr_Ser-Thr 5 eklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkkkekl 99 +lG G+fG+V+k++ k ++ + a K+++ + +e+e ++f+ e++++++++h+++v ++ ++++e++l++++e+++gG+L++ + + ++ l FUN_001593-T1 37 GELGDGSFGKVHKAERK----TDGTLAAAKIIDVK-DESELDDFMVEIDILSECKHSHVVGMYEAYYHENKLWMMLEFCSGGALDDLILEIERGL 126 68**************9....88889999999655.5555******************************************************* PP PK_Tyr_Ser-Thr 100 slkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekk.....ftsksDvWs 189 + +++ +++q+ + +++L+ +k++Hrdl a N L++++ +k++DfG++ + +++ +++++ WmapE++ +++ + k+D+Ws FUN_001593-T1 127 TEDQIKVVCRQMFECLHFLHTHKVIHRDLKAGNLLLTSDGNIKLADFGVSAKN--KKTVQRRTTFIGTPYWMAPEVIVTETckddpYDYKADIWS 219 **************************************************998..677777888888999******9988888899********* PP PK_Tyr_Ser-Thr 190 fGvllwEiftlgeepykglkneevlell..eegerleqpencpeelyelmkeCweedpeeRptfkelve 256 G++l+E+++ + py+++++ +vl ++ ++ +l+++++++++ +++++ C+ ++++ R + +l+e FUN_001593-T1 220 AGITLIELAE-MQPPYHDMHPMRVLFKIpkSDPPQLQAKNKWSKHFHDFLSLCVVKSADMRTSAGQLLE 287 ********99.89***************75556789**************************9988865 PP == domain 2 score: -5.2 bits; conditional E-value: 3.6 PK_Tyr_Ser-Thr 29 ikVavKtlkeeaseeekeefleeaklmkklsh 60 + a+K l++ ++e+++ + +e++ +k+ + FUN_001593-T1 1112 SESALKELQQLQNEKRHMLMESETTKLKERDE 1143 56688888777777755555557777776654 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.01 66 40 62 .. 41 64 .. 37 80 .. 0.80 2 ! 32.2 0.1 1.2e-11 7.9e-08 145 224 .. 104 185 .. 80 191 .. 0.85 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.01 ABC1 40 aASiaqVhkArlk.dgeeVavKvq 62 S++ VhkA+ k dg a K+ FUN_001593-T1 41 DGSFGKVHKAERKtDGTLAAAKII 64 57***********88988888886 PP == domain 2 score: 32.2 bits; conditional E-value: 1.2e-11 ABC1 145 vLtmeyvdGikiddlealeeagidrkeiaeklvel..fleqifedgffhaDphpGNllvrkdgelvllDfGlmgeldekfrk 224 +++e+++G ++ddl e+g+++++i ++ +l+ + +++++h D+ +GNll+++dg++ l DfG++++ ++ ++ FUN_001593-T1 104 WMMLEFCSGGALDDLILEIERGLTEDQIKVVCRQMfeCLHFLHTHKVIHRDLKAGNLLLTSDGNIKLADFGVSAKNKKTVQR 185 5899**********9998899999998877666652257889999***************************9998887766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1218 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4007 (0.15686); expected 510.9 (0.02) Passed bias filter: 665 (0.0260325); expected 510.9 (0.02) Passed Vit filter: 357 (0.0139753); expected 25.5 (0.001) Passed Fwd filter: 79 (0.00309258); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 1.45u 0.48s 00:00:01.93 Elapsed: 00:00:00.53 # Mc/sec: 9327.95 // Query: FUN_001594-T1 [L=588] Description: FUN_001594 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-20 71.9 0.3 7.2e-20 71.9 0.3 2.6 3 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain 1e-18 68.2 0.6 5.6e-18 65.8 0.1 2.6 3 Metallophos_C Iron/zinc purple acid phosphatase-like prote 2.7e-14 54.6 0.5 5.6e-14 53.5 0.5 1.6 1 Metallophos Calcineurin-like phosphoesterase ------ inclusion threshold ------ 0.012 16.2 0.7 0.46 11.1 0.7 2.8 1 fn3_PAP Fn3-like domain from Purple Acid Phosphatase Domain annotation for each model (and alignments): >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 1.1 6.7e+03 10 38 .. 42 70 .. 33 135 .. 0.59 2 ! 71.9 0.3 1.1e-23 7.2e-20 1 92 [. 166 266 .. 166 267 .. 0.93 3 ? -1.1 0.1 0.65 4.1e+03 6 30 .. 549 573 .. 547 585 .. 0.70 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.1 Pur_ac_phosph_N 10 gpstsmtvsWrtpeattspvvqygtsssa 38 +p++ + +++r++++ + v + + s+s+ FUN_001594-T1 42 NPANRLKFNFRPKPSAPDGVASLTVSPSS 70 55555555555555444444444444443 PP == domain 2 score: 71.9 bits; conditional E-value: 1.1e-23 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedl...........tsgyihsatltgLepgttYyYrvgdens 83 P q hl+ltg++t+m+++W++ ++ ++++v+ygt++ + + ++ s+tyt++d+ ++g+ih ++l++L+pg +YyY++g+e+ FUN_001594-T1 166 PLQGHLALTGDPTEMRIMWVSGTD-ATSIVKYGTNPYDWVTVTSNISKTYTANDMcappangpsfvDPGFIHDVLLRNLTPGSRYYYTYGSET- 257 789*********************.9**********7766666666889999999*************************************9. PP Pur_ac_phosph_N 84 gwsevysft 92 ++s++++f FUN_001594-T1 258 SMSSQHNFV 266 999999995 PP == domain 3 score: -1.1 bits; conditional E-value: 0.65 Pur_ac_phosph_N 6 lsltgpstsmtvsWrtpe.attspvv 30 l+l++ t++ +W+ ++ + + v FUN_001594-T1 549 LTLNT-RTELQWQWVENKsGQVKDSV 573 56666.99999***999723344444 PP >> Metallophos_C Iron/zinc purple acid phosphatase-like protein C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 2.4 1.5e+04 46 57 .. 135 146 .. 118 150 .. 0.61 2 ? -2.3 0.0 1.7 1.1e+04 36 58 .. 169 190 .. 167 193 .. 0.83 3 ! 65.8 0.1 8.7e-22 5.6e-18 1 63 [] 513 572 .. 513 572 .. 0.90 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 2.4 Metallophos_C 46 thLtwefvrssd 57 + +++++r+++ FUN_001594-T1 135 KECQFSYYRNDN 146 445677777755 PP == domain 2 score: -2.3 bits; conditional E-value: 1.7 Metallophos_C 36 GygrltvvNrthLtwefvrssdg 58 G+ lt + t+++ +v+ d FUN_001594-T1 169 GHLALTG-DPTEMRIMWVSGTDA 190 7888999.99********99776 PP == domain 3 score: 65.8 bits; conditional E-value: 8.7e-22 Metallophos_C 1 apvhiviGaAGniegsafkkdppqpewsafresdyGygrltvvNrthLtwefvrssdgsvlDs 63 apvhiv+G+AG + + +d+ + +ws f+e+dyGyg+lt +rt+L+w++v++++g+v Ds FUN_001594-T1 513 APVHIVVGTAGKDLD-T--EDYYPVPWSLFHENDYGYGKLTLNTRTELQWQWVENKSGQVKDS 572 8**********7777.2..244568***********************************997 PP >> Metallophos Calcineurin-like phosphoesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.5 0.5 8.7e-18 5.6e-14 4 194 .] 280 498 .. 277 498 .. 0.69 Alignments for each domain: == domain 1 score: 53.5 bits; conditional E-value: 8.7e-18 Metallophos 4 lvigDlH..gegqfddllelleklrpeekpdlvliaGDlvdrgsletevlellallvky...ipvflvrGNHd..................fydec 76 lv gD++ + + ++++++ ++ ++ + lv++ GD+ + + +++++al+ y +p+++ GNH+ f+ ++ FUN_001594-T1 280 LVYGDMGvsPKPRAYETADYAKREAETGSAALVIHHGDISYARGYAYIWEQWFALIEPYatiVPYMVGIGNHEqdhlsggfkdpsgapgegFHPWW 375 788999866666666666666666777899********999998888888888888888888***********88877664444444444333333 PP Metallophos 77 lrkygelnllarpwkaf......vevfnllplaaligg..killvhGglselvtlddirgldrprevpeegdlllsd.....arkkadwvivlgHa 159 ++ yg + v +f + ++++ + +++G ++ l + +++ p+ ++++++ +r ++wv++ gH+ FUN_001594-T1 376 APGYGT----------DsggecgVPMFYRFQMPDNGNAvwWYSFDYGS---IHFLMMSTENNFTAGSPQ--YEWMENdlksvNRTLTPWVVIAGHR 456 333333..........13333332233333332222224466666666...566666666677766666..9****99****************** PP Metallophos 160 ply.......rgasylfgpealrkllkrngvdlvlsGHtHvp 194 p+y +++ ++a+++ll +++vdl +++H H + FUN_001594-T1 457 PMYssqmahdDYVISIGIQKAFEDLLIEYEVDLAFWAHYHSY 498 ***66666666666666666666*****************86 PP >> fn3_PAP Fn3-like domain from Purple Acid Phosphatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.7 7.2e-05 0.46 63 110 .. 108 153 .. 63 160 .. 0.72 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 7.2e-05 fn3_PAP 63 ikykfanssaeylktgsgklkFrlinqRadfsFalfsgGlaePvlvav 110 + + ++nss+ y+k g g+ + rl n+R + +F+++++ + +lv FUN_001594-T1 108 LDFVHVNSSETYTK-GYGEFEVRLWNMRKECQFSYYRND-NYSMLVVR 153 56789999999997.99*******************964.33444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (588 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 492 (0.0192601); expected 510.9 (0.02) Passed bias filter: 424 (0.0165982); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 5720.43 // Query: FUN_001595-T1 [L=578] Description: FUN_001595 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.9e-19 68.4 3.5 2.4e-18 67.0 0.1 2.8 2 Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain 1e-14 55.9 5.1 1.8e-14 55.1 5.1 1.4 1 Metallophos Calcineurin-like phosphoesterase 9.3e-14 52.3 1.0 9.3e-14 52.3 1.0 3.1 3 Metallophos_C Iron/zinc purple acid phosphatase-like prote ------ inclusion threshold ------ 0.043 13.5 0.5 0.075 12.7 0.5 1.3 1 NCTSP_N Non-contractile tail sheath N-terminal domai Domain annotation for each model (and alignments): >> Pur_ac_phosph_N Purple acid Phosphatase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.7 0.18 1.1e+03 12 68 .. 76 156 .. 68 160 .. 0.48 2 ! 67.0 0.1 3.8e-22 2.4e-18 1 93 [] 165 265 .. 165 265 .. 0.96 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.18 Pur_ac_phosph_N 12 stsmtvsWrtpe..attspvvqygtsssa....lsstatatsstyttedl..................tsgyihsatltgL 68 +++vsW+ + ++t+ + y ++++ l+ ++ssty + ++ ++ yih at ++L FUN_001595-T1 76 GATVNVSWNGIPkaTHTDFIALYCPKDEIssgyLDYFYVTQSSTYASGYGwytvvvynmrttcefryyQESYIHVATSNEL 156 567777777643112233344455442223333344344444444433334444444444444444447777777776666 PP == domain 2 score: 67.0 bits; conditional E-value: 3.8e-22 Pur_ac_phosph_N 1 PeqvhlsltgpstsmtvsWrtpeattspvvqygtsssalsstatatsstyttedl...........tsgyihsatltgLepgttYyYrvgdens 83 P q h++ltg++t+m+v+W++ + + pvv+yg++s ++a+++s+ty+++ + ++gyih ++lt+L+p+ +Y+Y++g+++ FUN_001595-T1 165 PLQGHIALTGDPTQMRVMWVSGTG-DIPVVHYGETSLM-VFKAEGSSKTYNKSHMcgppastngftDPGYIHDVLLTDLSPSSQYFYSYGSSK- 255 7899*******************9.9*********955.789********99999**********999************************9. PP Pur_ac_phosph_N 84 gwsevysftT 93 +s+ ++f+T FUN_001595-T1 256 MMSSIRTFHT 265 9*******98 PP >> Metallophos Calcineurin-like phosphoesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.1 5.1 2.9e-18 1.8e-14 2 194 .] 276 494 .. 275 494 .. 0.66 Alignments for each domain: == domain 1 score: 55.1 bits; conditional E-value: 2.9e-18 Metallophos 2 rilvigDlH...gegqfddllelleklrpeekpdlvliaGDlvdrg....sletevlellallvkyipvflvrGNHd..............fydec 76 ++v gD++ ++g +d+ + ++e++ ++ + lv ++GD+ +++ + el+++ + ip+++ GNH+ +++ FUN_001595-T1 276 SFVVYGDMGlsvDPGAHDTAKYIIEEA-KK-GKSLVFHVGDISYARgygyIWDQ-WHELIEPYATLIPYMVGIGNHEqdhlsggskdpsgaPGEGW 368 6899*******9999999999999998.33.69********7666558899999.999989999999**********6654444333333311122 PP Metallophos 77 lrkygelnllarpwkaf....................vevfnllplaaliggkillvhGglselvtlddirgldrprevpeeg....dlllsd... 145 + +w +f ++ ++++ ++++ +++ + + +d++ + + +l++ FUN_001595-T1 369 ----------HPIWGNFgddsggecgvpmyyrfhmpdNGNAVWWYSFDYGSVHFVMMSTE------------HDYR------KgsrqYTWLEKdlk 436 ..........23333332222211111111111222222223333333333333333333............2222......23334999999999 PP Metallophos 146 ..arkkadwvivlgHaply.......rgasylfgpealrkllkrngvdlvlsGHtHvp 194 +r+k++w+++ gH+p+y +++ l+ + l++l+ +++vdl ++GH H + FUN_001595-T1 437 svDRNKTPWLVLGGHRPMYssqkvssDYFVSLYMQYYLEELFHDYKVDLAFWGHYHSY 494 99*****************99988888888888888888*****************86 PP >> Metallophos_C Iron/zinc purple acid phosphatase-like protein C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.5 0.34 2.2e+03 30 45 .. 120 134 .. 109 150 .. 0.74 2 ? -2.6 0.0 2.1 1.3e+04 36 57 .. 168 187 .. 167 190 .. 0.81 3 ! 52.3 1.0 1.5e-17 9.3e-14 1 62 [. 511 569 .. 511 570 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.34 Metallophos_C 30 fresdyGygrltvvNr 45 ++ s yG+ ++ v+N FUN_001595-T1 120 YA-SGYGWYTVVVYNM 134 44.44********995 PP == domain 2 score: -2.6 bits; conditional E-value: 2.1 Metallophos_C 36 GygrltvvNrthLtwefvrssd 57 G+ lt + t++++ +v+ + FUN_001595-T1 168 GHIALTG-DPTQMRVMWVSG-T 187 7777888.99*****99997.4 PP == domain 3 score: 52.3 bits; conditional E-value: 1.5e-17 Metallophos_C 1 apvhiviGaAGniegsafkkdppqpewsafresdyGygrltvvNrthLtwefvrssdgsvlD 62 +++hiv+G+AG + + ws ++e+dyGygr+ v N++ L++e+vr++d+ v D FUN_001595-T1 511 GTTHIVVGSAGFTLD-TE--GYYDVGWSRYHENDYGYGRVLVANKSALYYEWVRNKDNVVRD 569 699********6655.32..45688***********************************99 PP >> NCTSP_N Non-contractile tail sheath N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.5 1.2e-05 0.075 35 96 .. 391 452 .. 384 496 .. 0.79 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.2e-05 NCTSP_N 35 flrkddlaGliWesedrldhpllayetdrdyrrttlrfrWrssgvlaldavngptltieGrd 96 f+ d+ + W s d + ++ +t++dyr+ + ++ W ++++++d+ + p l + G+ FUN_001595-T1 391 FHMPDNGNAVWWYSFDYGSVHFVMMSTEHDYRKGSRQYTWLEKDLKSVDRNKTPWLVLGGHR 452 6666666778899****9999************************************99974 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (578 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 551 (0.0215698); expected 510.9 (0.02) Passed bias filter: 408 (0.0159718); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5587.41 // Query: FUN_001596-T1 [L=185] Description: FUN_001596 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-21 75.5 0.2 9.1e-21 75.3 0.2 1.0 1 VWA von Willebrand factor type A domain 7.4e-07 30.2 0.0 1.3e-06 29.4 0.0 1.4 1 VWA_2 von Willebrand factor type A domain ------ inclusion threshold ------ 0.023 14.5 0.3 0.036 13.9 0.3 1.2 1 TMP-TENI Thiamine monophosphate synthase 0.041 14.7 0.0 0.13 13.0 0.0 1.8 2 Phycodna_minor_capsid Phycodnaviridae minor capsid protein 0.12 12.8 0.1 0.25 11.7 0.1 1.5 1 Hpr_kinase_N HPr Serine kinase N terminus Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.3 0.2 1.8e-24 9.1e-21 20 169 .. 1 165 [. 1 170 [. 0.90 Alignments for each domain: == domain 1 score: 75.3 bits; conditional E-value: 1.8e-24 VWA 20 vkeflkklvesldigpdstrvglvqyssevrtefslndys..skeellsavks.lkykgggttntgkalkyalenlfkssagaRe.....gapkvv 107 +k+++ +l++ +++ + +r+g+v yss++ + +s ++ + ++l++++k+ ++y gggt+ tg al +a++ l+ks++ ++ ++++ FUN_001596-T1 1 MKKMVIELIRHFSVRRSYARIGIVRYSSSADEIMSPQASQrrGFAALQRKLKKrMPYPGGGTR-TGLALGKAYSMLMKSRRQLKKfrkirKYEQNC 95 799*********************************99996566*******984688888888.******************55555599****** PP VWA 108 vlltdGksqd.gdveeaarelksagvkvfavgv.........gnadeeeLekiasepdeghvftvedfeale 169 +++tdG s+d + +e+ +++lk+ kv+avgv ++ e+eL++ia++++ + +f ++fe+l+ FUN_001596-T1 96 IVITDGLSNDrKRLERTSKQLKKI-AKVIAVGVrgknyskaqRKKQEKELKMIATNKN-KDFFLKDSFEKLR 165 **********77**********87.9***************88888888********9.9999999999776 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 0.0 2.6e-10 1.3e-06 23 107 .. 4 101 .. 1 103 [. 0.73 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 2.6e-10 VWA_2 23 aakdaveallkslpgdrvglvtfsdnpevlipltkdkakllealrrleat.....gggtdlaaAlqlarkalkkrr........rknakriivlit 105 ++ ++++ + ++ r+g+v +s+++ +++++ ++ + +al+r ++ gggt+++ Al +a ++l k r +++++ ++it FUN_001596-T1 4 MVIELIRHFSVRRSYARIGIVRYSSSADEIMSPQASQRRGFAALQRKLKKrmpypGGGTRTGLALGKAYSMLMKSRrqlkkfrkIRKYEQNCIVIT 99 3344444444455678***********999999755555444444444444666****************99766668999999778888888899 PP VWA_2 106 Dg 107 Dg FUN_001596-T1 100 DG 101 98 PP >> TMP-TENI Thiamine monophosphate synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.3 7.1e-06 0.036 2 66 .. 96 162 .. 95 168 .. 0.84 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 7.1e-06 TMP-TENI 2 ylvtdekldeeellevveealkg..gvtlvqlRekelddrellelakklaalcrkygvpliinDrvd 66 ++td +++++ le+ ++ lk +v +v +R k+ ++++++++ k+l+ ++++++ ++++D ++ FUN_001596-T1 96 IVITDGLSNDRKRLERTSKQLKKiaKVIAVGVRGKNYSKAQRKKQEKELKMIATNKNKDFFLKDSFE 162 56788767778888888888887334778889********************************876 PP >> Phycodna_minor_capsid Phycodnaviridae minor capsid protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 2.6e-05 0.13 37 79 .. 26 67 .. 4 73 .. 0.76 2 ? -1.8 0.0 1.1 5.7e+03 31 64 .. 85 117 .. 70 136 .. 0.54 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2.6e-05 Phycodna_minor_capsid 37 ynkandflwkiyvakglkgvaaedaklakkypylGyGdftGlr 79 y ++ d + + ++ +g aa ++kl+k+ py+G G tGl FUN_001596-T1 26 YSSSADEIMSPQASQ-RRGFAALQRKLKKRMPYPGGGTRTGLA 67 555555553555555.79***********************96 PP == domain 2 score: -1.8 bits; conditional E-value: 1.1 Phycodna_minor_capsid 31 fsrdldynkandflwkiyvakglkgvaaedakla 64 f + ++y+++ ++ + ++ k + ++l+ FUN_001596-T1 85 FRKIRKYEQNCIVI-TDGLSNDRKRLERTSKQLK 117 34444444433333.4444444444444444444 PP >> Hpr_kinase_N HPr Serine kinase N terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 4.9e-05 0.25 59 96 .. 71 108 .. 70 124 .. 0.85 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 4.9e-05 Hpr_kinase_N 59 sYlkklseeerkerleklfsyeipciIvtrgleppeel 96 +Y + ++++++ ++++k+ +ye ci++t+gl + + FUN_001596-T1 71 AYSMLMKSRRQLKKFRKIRKYEQNCIVITDGLSNDRKR 108 5888899************************9976554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1880 (0.0735956); expected 510.9 (0.02) Passed bias filter: 792 (0.0310041); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1827.38 // Query: FUN_001597-T1 [L=134] Description: FUN_001597 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00054 20.2 14.2 0.0008 19.6 14.2 1.2 1 Collagen Collagen triple helix repeat (20 copies) ------ inclusion threshold ------ 0.24 11.8 11.6 0.28 11.6 11.6 1.1 1 Sigma70_ner Sigma-70, non-essential region 1 9.9 16.2 1.2 9.7 16.2 1.1 1 YL1 YL1 nuclear protein 6.6 5.4 14.8 7.1 5.3 14.8 1.0 1 CDC45 CDC45 Domain annotation for each model (and alignments): >> Collagen Collagen triple helix repeat (20 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 14.2 1.3e-07 0.0008 27 53 .. 91 117 .. 86 126 .. 0.38 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 1.3e-07 Collagen 27 kGekGpaGekGppGaaGkpGapGekGe 53 kGe+G++GekG++G++Gk+G++G+kG+ FUN_001597-T1 91 KGEQGNKGEKGKKGKKGKKGKKGKKGK 117 222222222222222222222222222 PP >> Sigma70_ner Sigma-70, non-essential region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 11.6 4.4e-05 0.28 25 97 .. 25 103 .. 16 128 .. 0.71 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.4e-05 Sigma70_ner 25 iidGflDeeleeeeeaeeeeeeeeeeeeeeeeeddddeedeeseeadegelkeealekfeelreqyeklrk...........al 97 +++fl+ +++ ++e +e ++ ++++dd+d + +++++++ +e+ ++a + f+el + ++ FUN_001597-T1 25 SVSAFLN-----DDATNDEPIAEMGTDMHDDDDDDHDHDLDDELDDEAEEDEQQATSLFNELYKRSKEKAGkgeqgnkgekgKK 103 5677777.....455666666677777777777777788999********************8877654433766654433322 PP >> YL1 YL1 nuclear protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 16.2 0.00019 1.2 41 119 .. 49 129 .. 15 134 .] 0.30 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00019 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx.xxxxxxxxxxx.........xxxxxxxxx RF YL1 41 eeeedeesDsdfdsseddeeseeeedeeegekelqrqekkkr...kkekkrkaqkkkkklkk.kaakkkkkkid.........akepkpkkk 119 ++++d+ D d+d++ dde +e+e++ +el ++ k+k + + +k +k kk +k k +k k + + ++kk FUN_001597-T1 49 DDDDDD-HDHDLDDELDDEAEEDEQQATSLFNELYKRSKEKAgkgE--QGNKGEKGKKGKKGkKGKKGK----KgkgnlegsvK----KNKK 129 111111.333333333333322222222222233333333332221..222211111111111111222....12333434322....2222 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 14.8 0.0011 7.1 125 200 .. 44 115 .. 16 134 .] 0.28 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0011 CDC45 125 leeeeeedeedeeeeeeddeeeeeeeeeeedeeeeeedeeeskkkrksesdeeeeeeddeeersrkrrrseesakk 200 ++++++d ++++++d ++e ++e eede++ + +e k++k+++ + e+ ++ e+ ++ k+ ++ ++ kk FUN_001597-T1 44 GTDMHDDD----DDDHDHDLDDELDDEAEEDEQQATSLFNELYKRSKEKAGKGEQGNKGEKGKKGKKGKKGKKGKK 115 12222222....2222222222222222222222222222222222222222222111122222222222211111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1385 (0.054218); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1338.45 // Query: FUN_001598-T1 [L=91] Description: FUN_001598 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-22 78.5 8.1 6.7e-22 78.0 8.1 1.2 1 COX17 Cytochrome C oxidase copper chaperone (COX17) ------ inclusion threshold ------ 0.099 12.8 0.0 0.099 12.8 0.0 1.1 1 Neugrin Neugrin Domain annotation for each model (and alignments): >> COX17 Cytochrome C oxidase copper chaperone (COX17) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.0 8.1 5.2e-26 6.7e-22 1 47 [] 46 91 .] 46 91 .] 0.97 Alignments for each domain: == domain 1 score: 78.0 bits; conditional E-value: 5.2e-26 COX17 1 kklKpCCaCpeekkaRDeCilesgaeekCkelieaykaCmrslGFkv 47 kklKpCCaCpe+kk RD+Ci+e+g ee+C eliea+k+Cmr++GF+v FUN_001598-T1 46 KKLKPCCACPETKKVRDACIVEHG-EENCGELIEAHKECMRKMGFNV 91 699*********************.99******************97 PP >> Neugrin Neugrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 7.8e-06 0.099 48 82 .. 27 61 .. 13 86 .. 0.83 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 7.8e-06 Neugrin 48 rvlkskfvPtleqklkqdqkvlkkaglareiqqlp 82 + + s +vP+le+k kq++k lk ++e ++++ FUN_001598-T1 27 KAINSPLVPSLEEKPKQEKKKLKPCCACPETKKVR 61 567899*****************998888877766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (91 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 989 (0.038716); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.35s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 908.78 // Query: FUN_001599-T1 [L=774] Description: FUN_001599 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-93 313.1 6.6 5.7e-93 312.5 6.6 1.3 1 Sec15_C Exocyst complex subunit Sec15 C-terminal 9.1e-58 195.4 3.6 2.4e-57 194.1 3.6 1.7 1 EXOC6_Sec15_N Exocyst complex component EXOC6/Sec15, N-ter 0.00027 21.4 0.1 0.00098 19.5 0.1 2.0 1 Sec8_N Exocyst complex component Sec8 N-terminal 0.00029 21.3 1.3 0.033 14.8 0.1 3.4 2 VPS51_Exo84_N Vps51/EXO84/COG1 N-terminal 0.0012 19.6 1.4 0.0038 17.9 0.2 2.5 2 COG5_N Conserved oligomeric Golgi complex subunit 5 ------ inclusion threshold ------ 0.017 15.4 0.1 0.049 13.9 0.1 1.7 2 MIF4G_like MIF4G like 0.12 13.1 0.2 7.8 7.3 0.1 2.6 2 DUF5991 Family of unknown function (DUF5991) 0.41 11.1 4.4 0.51 10.8 0.4 3.0 2 Histone_HNS_N H-NS histone-like proteins, N-terminal domai 0.77 11.0 3.3 1.5 10.1 0.3 2.7 2 NagJ_C Hyaluronidase post-catalytic domain-like 1.5 9.1 3.0 23 5.3 0.3 3.3 3 Ribosomal_L12_N Ribosomal protein L7/L12 dimerisation domain 4.4 8.0 5.6 11 6.8 0.0 3.7 4 DUF2097 Uncharacterized protein conserved in archaea Domain annotation for each model (and alignments): >> Sec15_C Exocyst complex subunit Sec15 C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 312.5 6.6 2.4e-96 5.7e-93 2 348 .] 383 730 .. 382 730 .. 0.96 Alignments for each domain: == domain 1 score: 312.5 bits; conditional E-value: 2.4e-96 Sec15_C 2 LyelllelfekYaelllkkfskdfeeilseDdymplvveneeeyekvlkvcwlekeelesepfpvtlPFSqlyplcCidirsfiekfykFledlsq 97 + ++lle++++Y+e+l k+++ f++i++eD+y+p+ e+e++y+++lk +++e +++ + +fp++lPFS+ +++++++++++i+ ++kF e+l FUN_001599-T1 383 IFDVLLEMRHQYNEILSKDWEAIFKNIFDEDNYTPILCEDESQYSAILKEFPFE-DSELQGSFPRHLPFSEGMIKVYKEVKHYIDSCLKFNENLNV 477 5799*************************************************6.6667778********************************77 PP Sec15_C 98 hereideilrksldellikvvseslreklkst.lnlsqiaQiliNleyfekackelekllaelrsiqrrsaggeiklkaskefkaarkaAekrife 192 +++ei + +rks++ ll+++++ ++ + ++++ +++ q++Q+ iN+ ++e ac +le++++ +++++++ ++ ++ ++fk+ r +Ae++++e FUN_001599-T1 478 SQTEIGDSVRKSTNLLLTRTLNVCITSLIRKQeVSIPQLVQMSINTIHLEAACVHLEEYVSGTTGTSSE-ITNVSRVYGLSTFKDVRAEAEQQVYE 572 77**********************************************************999997774.59999********************* PP Sec15_C 193 lvnsKiddflelaeyDWtpteaekepseylkdliafLetifsstlvnLpesvkelvyfraldhiaeslldlllseevkrinenavsnldlDvkyle 288 +n Ki +fl+la+y+W p++++ ++s+yl dl+++L+t+f + ++ Lp +v++++++++++++a++l ++ll++evk++n+ ++++++ D++ +e FUN_001599-T1 573 RLNMKIAEFLDLANYNWAPDNSRLHASSYLVDLLDYLQTTFLN-FSTLPGNVAQTACMSSCKYLATKLREMLLDDEVKQMNASGLKAFNQDLRKCE 667 *******************************************.99************************************************** PP Sec15_C 289 sf.....vkglkeskslslestfaelrqlidLllsdnveeY.ldpsirerkYsrvkpekaaalleK 348 +f v+g++e l++tf elrqlidLll++++++Y +d + ++kYsrv+p +a+lleK FUN_001599-T1 668 EFansnpVEGINEG---ILQMTFLELRQLIDLLLNEDWSTYfADHGSTSSKYSRVNPYVVAKLLEK 730 **777777777666...99**********************************************9 PP >> EXOC6_Sec15_N Exocyst complex component EXOC6/Sec15, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 194.1 3.6 1e-60 2.4e-57 1 170 [] 45 214 .. 45 214 .. 0.99 Alignments for each domain: == domain 1 score: 194.1 bits; conditional E-value: 1e-60 EXOC6_Sec15_N 1 kLnelvkkkdeeieelcnenyqefissvdellsvrkeaeeLkseiaelneslqksgeellekkkelleakkvskniseaiellkkclqvlelvnkv 96 kL+e+++ +d++ie++cn +yq fi+sv+ell+vr ea++Lk +++e+ne +q+sg+el++k ++l++++++++ni +aie+l+ cl+vle++ k+ FUN_001599-T1 45 KLEERIRVHDKDIERMCNYHYQGFIESVNELLKVRGEARKLKMRVKEVNEAMQESGRELASKCENLIQCRTTQRNIVSAIETLSVCLPVLEMYAKL 140 699********************************************************************************************* PP EXOC6_Sec15_N 97 qelikekkyykALktldeLekihlkevenfefakkieksiPslkksikdevmsdlkewLvnirkkskkiGelaf 170 ++++k+++yy+ALktl++Le+++l+++++f+fa+ +++siP+l+++ik++++++l+++L++irk+s+k+G++a+ FUN_001599-T1 141 KDQMKNRRYYPALKTLEQLEHTYLPRIKRFRFAEIMQESIPVLREHIKEASLAELRDFLEKIRKVSEKLGSIAM 214 **********************************************************************9986 PP >> Sec8_N Exocyst complex component Sec8 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 4.2e-07 0.00098 42 139 .. 43 140 .. 33 143 .. 0.87 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 4.2e-07 Sec8_N 42 lkefkqlkkqieeaLqevvnehhqaFnssiasYskilssiqesqekvselKesleeakkklstkkkeLkelnersakykevieiLdaieelkkvpd 137 ++++++ + +++++ + n h+q+F +s+ k+ + + +v+e+ e+++e+ ++l k ++L + ++ ++ ie+L+ + ++ FUN_001599-T1 43 MDKLEERIRVHDKDIERMCNYHYQGFIESVNELLKVRGEARKLKMRVKEVNEAMQESGRELASKCENLIQCRTTQRNIVSAIETLSVCLPVLEMYA 138 55556666666789999********************************************************************97766666666 PP Sec8_N 138 ki 139 k+ FUN_001599-T1 139 KL 140 65 PP >> VPS51_Exo84_N Vps51/EXO84/COG1 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.1 1.4e-05 0.033 29 83 .. 44 98 .. 35 101 .. 0.93 2 ? 3.5 0.1 0.047 1.1e+02 12 38 .. 183 209 .. 177 220 .. 0.89 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.4e-05 VPS51_Exo84_N 29 sslrseieeldeelkqlVydnYrdlikaadtiskmksemeqleqklselkqalek 83 +l+ i+ d+++ ++++ +Y+ +i+ +++ k ++e ++l+ +++e ++a+++ FUN_001599-T1 44 DKLEERIRVHDKDIERMCNYHYQGFIESVNELLKVRGEARKLKMRVKEVNEAMQE 98 689999**********************************************986 PP == domain 2 score: 3.5 bits; conditional E-value: 0.047 VPS51_Exo84_N 12 vsellskstleellqlesslrseieel 38 ++e +++++l+el+ + +++r+ e l FUN_001599-T1 183 LREHIKEASLAELRDFLEKIRKVSEKL 209 678899***************998876 PP >> COG5_N Conserved oligomeric Golgi complex subunit 5, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.2 1.6e-06 0.0038 36 132 .] 44 140 .. 37 140 .. 0.96 2 ? -2.1 0.1 2.5 5.9e+03 47 71 .. 185 209 .. 176 252 .. 0.63 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.6e-06 COG5_N 36 krlkydiqeldkrieqlitsnhleLleqlskikeassilselksslesLsasyerlksevlepyeeaeklqsalkrlhqtleLlrallrflhLskq 131 +l++ i+ dk ie+ ++ +++ +e +++ + ++ +lk ++++++++++ +e+ + e++ + ++++ ++ ++ e+l l +l + ++ FUN_001599-T1 44 DKLEERIRVHDKDIERMCNYHYQGFIESVNELLKVRGEARKLKMRVKEVNEAMQESGRELASKCENLIQCRTTQRNIVSAIETLSVCLPVLEMYAK 139 6899999******************************************************************************99999999888 PP COG5_N 132 L 132 L FUN_001599-T1 140 L 140 7 PP == domain 2 score: -2.1 bits; conditional E-value: 2.5 COG5_N 47 krieqlitsnhleLleqlskikeas 71 ++i++ ++ + le+++k +e+ FUN_001599-T1 185 EHIKEASLAELRDFLEKIRKVSEKL 209 5555555555555555555544432 PP >> MIF4G_like MIF4G like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.1 2.1e-05 0.049 90 149 .. 323 381 .. 309 396 .. 0.86 2 ? -3.5 0.0 4.7 1.1e+04 26 49 .. 595 617 .. 592 633 .. 0.72 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 2.1e-05 MIF4G_like 90 vyyhsllteicklaPkavaPslGrairllysalssldlelierfldWfshhlsnfgftWk 149 + s + ++ ++a + +aP+l + + y + sl +++ + ++ Wf+h ls fgf+ k FUN_001599-T1 323 LVTRSTVDDLWEMAAAKIAPVLLTCTQSAYCEDPSLLIKI-KELIVWFCHTLSGFGFNVK 381 455788889999************************9886.67888***********865 PP == domain 2 score: -3.5 bits; conditional E-value: 4.7 MIF4G_like 26 rkeaakllldldlyltkktfalra 49 r +a+ +l+dl yl++ tf + + FUN_001599-T1 595 RLHASSYLVDLLDYLQT-TFLNFS 617 77899999999999975.555444 PP >> DUF5991 Family of unknown function (DUF5991) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.1 0.0034 7.8 26 98 .. 49 122 .. 34 134 .. 0.85 2 ? 3.0 0.0 0.073 1.7e+02 63 111 .. 366 413 .. 359 423 .. 0.74 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0034 DUF5991 26 tltikkengeyycaleieGlqtaeeilckvkgdenrikvkfekylpgdelnk.erykegepLlsLeregskltt 98 ++ + ++ e+ c+++ +G+ +++ l kv g+ ++k++ +++++ ++ + e ++ e+L++ + ++ ++++ FUN_001599-T1 49 RIRVHDKDIERMCNYHYQGFIESVNELLKVRGEARKLKMRVKEVNEAMQESGrELASKCENLIQCRTTQRNIVS 122 67788888899**********************************99887767888999999888888777766 PP == domain 2 score: 3.0 bits; conditional E-value: 0.073 DUF5991 63 kvkfekylpgdelnkerykegepLlsLeregsk.ltteWgaltPalaene 111 v f +l+g + ++ k ++Ll+++ + ++ l ++W+a+ +++ +++ FUN_001599-T1 366 IVWFCHTLSGFGF--NVKKIFDVLLEMRHQYNEiLSKDWEAIFKNIFDED 413 5566666666655..6778889********5554999*****98776655 PP >> Histone_HNS_N H-NS histone-like proteins, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.3 0.79 1.8e+03 5 66 .. 76 97 .. 72 106 .. 0.57 2 ? 10.8 0.4 0.00022 0.51 12 40 .. 181 209 .. 176 222 .. 0.85 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.79 Histone_HNS_N 5 lkiLtnkrrLRaaakelsleeLeevlekLqevieerreeeeaeekeeaekeekieeikklme 66 lk+ + +r+L+ +ke+ + m+ FUN_001599-T1 76 LKVRGEARKLKMRVKEV----------------------------------------NEAMQ 97 55555555555555554........................................44444 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00022 Histone_HNS_N 12 rrLRaaakelsleeLeevlekLqevieer 40 LR +ke sl+eL++ lek+ +v e+ FUN_001599-T1 181 PVLREHIKEASLAELRDFLEKIRKVSEKL 209 579**********************9875 PP >> NagJ_C Hyaluronidase post-catalytic domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 0.9 2.1e+03 7 47 .. 66 106 .. 62 119 .. 0.79 2 ? 10.1 0.3 0.00063 1.5 33 103 .. 176 245 .. 171 249 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.9 NagJ_C 7 dalwekvekgedlsaeaeaLkeefekmkeaadkLranLpne 47 + ++e+v++ +++ ea++Lk +++++ ea ++ ++L ++ FUN_001599-T1 66 QGFIESVNELLKVRGEARKLKMRVKEVNEAMQESGRELASK 106 56888888888999999999999999999999888888764 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00063 NagJ_C 33 mkeaadkLranLpnekLsecsaqLdkLerlgeagktalellkaqlngdteavselkselqkklkeldssea 103 m+e+ Lr++ +++ L+e ++ L+k++++ e+ + ++++ +a+++++ + vs ++ + + + +eld+s++ FUN_001599-T1 176 MQESIPVLREHIKEASLAELRDFLEKIRKVSEK-LGSIAMNQAIQKNNLTLVSGISLKKKGEDEELDKSPQ 245 8899999*********************99875.8899*********999999988888888888888887 PP >> Ribosomal_L12_N Ribosomal protein L7/L12 dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.82 1.9e+03 3 14 .. 118 129 .. 116 130 .. 0.86 2 ? 1.8 0.1 0.12 2.8e+02 7 24 .. 185 202 .. 182 205 .. 0.86 3 ? 5.3 0.3 0.0098 23 5 24 .. 678 697 .. 675 700 .. 0.86 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.82 Ribosomal_L12_N 3 eeiveaiselTl 14 +iv ai++l++ FUN_001599-T1 118 RNIVSAIETLSV 129 68********98 PP == domain 2 score: 1.8 bits; conditional E-value: 0.12 Ribosomal_L12_N 7 eaiselTllElseLvkaL 24 e i+e +l El ++ +++ FUN_001599-T1 185 EHIKEASLAELRDFLEKI 202 78***********98876 PP == domain 3 score: 5.3 bits; conditional E-value: 0.0098 Ribosomal_L12_N 5 iveaiselTllElseLvkaL 24 i e i ++T lEl +L+++L FUN_001599-T1 678 INEGILQMTFLELRQLIDLL 697 567799***********987 PP >> DUF2097 Uncharacterized protein conserved in archaea (DUF2097) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.2 1.7 4e+03 12 28 .. 257 273 .. 254 275 .. 0.90 2 ? 6.8 0.0 0.0047 11 59 78 .. 377 396 .. 365 400 .. 0.88 3 ? -3.5 0.1 7.8 1.8e+04 7 27 .. 458 478 .. 454 479 .. 0.78 4 ? 1.4 0.0 0.22 5e+02 16 43 .. 509 537 .. 506 562 .. 0.75 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.7 DUF2097 12 eYikdnvkegdlleisy 28 Yi v e ++ ei+y FUN_001599-T1 257 LYIFTVVGERETFEIYY 273 59999***********9 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0047 DUF2097 59 evdlekikddllElehipee 78 ++++ki d llE++h ++e FUN_001599-T1 377 GFNVKKIFDVLLEMRHQYNE 396 689*************8876 PP == domain 3 score: -3.5 bits; conditional E-value: 7.8 DUF2097 7 eeelieYikdnvkegdlleis 27 ++e+ Yi+ +k ++ l +s FUN_001599-T1 458 YKEVKHYIDSCLKFNENLNVS 478 689999999888888877775 PP == domain 4 score: 1.4 bits; conditional E-value: 0.22 DUF2097 16 dnvkegdlleisygrvyipGevlsiek.v 43 ++v l+++s++ ++ + ++ e+ v FUN_001599-T1 509 QEVSIPQLVQMSINTIHLEAACVHLEEyV 537 577778899**********9999998843 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (774 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1469 (0.0575064); expected 510.9 (0.02) Passed bias filter: 838 (0.0328049); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.43u 0.38s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7308.13 // Query: FUN_001600-T1 [L=362] Description: FUN_001600 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.02 16.0 0.7 0.048 14.8 0.7 1.7 1 SCVP Secreted clade V proteins 0.096 12.9 7.8 0.34 11.2 5.2 2.2 2 HAUS1 HAUS augmin-like complex subunit 1 1.9 9.6 13.7 1.5 10.0 5.0 3.1 3 YabA Initiation control protein YabA Domain annotation for each model (and alignments): >> SCVP Secreted clade V proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.7 5.7e-06 0.048 26 94 .. 97 168 .. 76 170 .. 0.74 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 5.7e-06 SCVP 26 llkeyakslgisydk.revresatnvgGkfavkytllgadCeqvkefvkka..ksessfitsatvkCgskts 94 l+ ++++l+ +++ r + + n g k+ +yt ++C+++++++++a +e++ t+++ Cg ++ FUN_001600-T1 97 NLEVLFSELKEKFEIdRRNLQFCLNLGTKLYQEYTYYKKTCKKLQQYTQEAkcEQEAFRATEIHKHCGAQPL 168 3444444444444443445556999***********99*************888999999999999*99985 PP >> HAUS1 HAUS augmin-like complex subunit 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 5.2 3.9e-05 0.34 108 195 .. 52 139 .. 50 144 .. 0.90 2 ? 2.3 0.1 0.02 1.7e+02 52 113 .. 145 203 .. 136 211 .. 0.66 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 3.9e-05 HAUS1 108 aindltselleveeknreeerelkelkkkltkalkklkqlkkdlkkleeeleaekaklekreknlkflkkKseeykkrikkleeqlaa 195 ain + ++ +++++ +r+l++lk++l k ++ +l+k+ ++le + k+k+e + +nl+f + ++ ++++ ++++ ++ FUN_001600-T1 52 AINWQRYAQGRLTDEMKQSKRQLERLKADLVKKEGRNATLQKEYHNLEVLFSELKEKFEIDRRNLQFCLNLGTKLYQEYTYYKKTCKK 139 666677777889999*****************************************************99999999999999887766 PP == domain 2 score: 2.3 bits; conditional E-value: 0.02 HAUS1 52 kaaeYkaeakrlqeileslglspesLssegsrslntLassAllLelkdtslssfllaindlt 113 ++a++++ea r +ei ++ g +p s++++ +L s++ L+++ +s s + +t FUN_001600-T1 145 QEAKCEQEAFRATEIHKHCGAQPLSITQSKI---MALEPSSESLKVNAPSAVSVAPDYTSMT 203 4455667777777777777777777776655...5677788888888888877777666666 PP >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.2 0.0082 70 12 50 .. 12 50 .. 2 62 .. 0.84 2 ? 10.0 5.0 0.00017 1.5 12 79 .. 62 129 .. 58 152 .. 0.84 3 ? -2.9 0.0 1.7 1.5e+04 54 60 .. 329 335 .. 306 344 .. 0.50 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.0082 YabA 12 eleeqleellkeleelkeelaelleenaeLeiEnekLre 50 +l + +++ + +++l +e + ll++n+ L++E +k++ FUN_001600-T1 12 QLLQIINQQQLGIQSLINERKWLLDDNHILRVEIDKIKV 50 566778888889999999***************999875 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00017 YabA 12 eleeqleellkeleelkeelaelleenaeLeiEnekLrerlkkeeekekekkkelsegkenLaklYee 79 +l++++++ ++le+lk++l + +na+L+ E ++L +++ +ek + ++++l+ + +klY+e FUN_001600-T1 62 RLTDEMKQSKRQLERLKADLVKKEGRNATLQKEYHNLEVLFSELKEKFEIDRRNLQFCLNLGTKLYQE 129 578899*******************************9999777766666666666666666677776 PP == domain 3 score: -2.9 bits; conditional E-value: 1.7 YabA 54 keeekek 60 +++e++k FUN_001600-T1 329 EAQEEKK 335 1111111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1620 (0.0634175); expected 510.9 (0.02) Passed bias filter: 638 (0.0249755); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.45s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 3508.17 // Query: FUN_001603-T1 [L=530] Description: FUN_001603 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-92 310.9 0.3 2e-92 310.6 0.3 1.0 1 GDA1_CD39 GDA1/CD39 (nucleoside phosphatase) family Domain annotation for each model (and alignments): >> GDA1_CD39 GDA1/CD39 (nucleoside phosphatase) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 310.6 0.3 7.9e-97 2e-92 5 420 .. 55 480 .. 51 483 .. 0.87 Alignments for each domain: == domain 1 score: 310.6 bits; conditional E-value: 7.9e-97 GDA1_CD39 5 kenekYgivlDAGSsgsrlfvykfkdek.eellqivklieevkkle.....PGlSsfaekpeeaaeyleplle.laeeviPeekrsetpvllkATA 93 k +++YgivlDAGSs++++f+yk+ + + + v++i e+++++ G+Ss++ +pe+a+++l+ ++e a+++iP ++++p++l+ATA FUN_001603-T1 55 KVKDEYGIVLDAGSSHTQMFIYKWSVGDiIKGTALVNQIGECTVTDeaghiRGISSYK-NPEDAGKSLNGCIEnKAKKLIPSYIQDKSPIYLGATA 149 55789*******************66541455778889999777653333359****6.699**********8469******************** PP GDA1_CD39 94 GlRLlke...ekkekilkalrnklkklssfkvkdqgiriidGeeEGiysWiaiNYllGkfnkea....sesskqetvgvlDlGGaStQiafeiqee 182 G+RLl+e e+ +kilk++r+ l + s+f +kd+ +rii GeeEGi sWi++NYl ++ + ++ sk+ t g+lD+GGaStQi+f+++ FUN_001603-T1 150 GMRLLNEtdfEATSKILKSVRKALAS-SPFMFKDEYARIISGEEEGISSWITLNYLKHALDLSVegnqNQDSKEGTYGALDMGGASTQITFVPT-- 242 *****984445678888888888865.7899*************************9988765444447778899*******************.. PP GDA1_CD39 183 sakaekvedieelklqekledkkYklyvtsfLgYGanealrkklakliknasee.vlkdpClprglekvvevsdle............fkqfaikg 265 + a+k +i l +k+Y+ y++sfL+YG+ ea+r+ a+l+k a+ e + +pC+p+g++k v+ + + ++++ g FUN_001603-T1 243 -KPAQKQTEI-------VLFGKEYEPYTHSFLCYGLTEAQRRFFAQLLKDAKPEtSVGNPCAPKGYHKNVTSNYVWatpcvqehnkpgLTNYTVMG 330 .455555555.......57899***************************9987659**************99988899**********9******* PP GDA1_CD39 266 tgnyeqCrksikellnknakCkae.eCafngvfapsidllqklfgaseyfYtvsdvlklggekvkleklteaakkfCkknweeikssfkkskekni 360 tgny C +++++l+n ++C++ +C+f++v+ p+ +f a++ fY v l+l+++ +l++l++a k++C+k+wee+ + + + FUN_001603-T1 331 TGNYTLCAQKVRKLFN-FTSCHDRkNCSFDAVYLPP--TDGVTFLAFSGFYGVIRDLNLTRNV-SLQELQNASKSICEKTWEEMLDIPSA-NRDLQ 421 ****************.566655449**********..4456899999*************99.********************986555.44555 PP GDA1_CD39 361 seeelCfkgayilslLhdGfdldkt.keelqsvkkiaekevgWtLGamlnlvkalklkkkl 420 s ++Cf+++yil+lL +G+++++t l++v+ i+++ vgW+LG m+n +k l+l ++ FUN_001603-T1 422 S--TYCFDAQYILTLLSKGYHFNNTqAATLRFVSSINQHSVGWALGFMINATKLLHLLPPV 480 5..8********************9889***********************9988776555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (530 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 980 (0.0383637); expected 510.9 (0.02) Passed bias filter: 840 (0.0328831); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5057.50 // Query: FUN_001604-T1 [L=564] Description: FUN_001604 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-27 95.1 45.1 9.3e-08 32.5 2.6 6.3 6 zf-H2C2_2 Zinc-finger double domain 3.7e-20 71.6 46.5 1.9e-05 25.4 1.9 6.8 6 zf-C2H2 Zinc finger, C2H2 type 5.1e-11 42.8 43.8 0.0019 19.2 1.3 6.6 7 zf-C2H2_4 C2H2-type zinc finger 2.2e-06 28.2 26.9 0.046 14.4 2.2 6.4 6 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding 2.9e-06 27.6 14.6 0.35 11.4 0.3 4.7 4 zf-C2H2_15 C2H2 zinc finger 2.5e-05 24.9 35.4 0.043 14.6 1.3 6.5 5 zf-met Zinc-finger of C2H2 type 0.00047 20.5 36.3 0.005 17.3 1.4 5.3 5 zf-C2H2_6 C2H2-type zinc finger 0.006 16.7 22.0 0.56 10.5 0.3 6.0 6 zf-C2HC_2 zinc-finger of a C2HC-type ------ inclusion threshold ------ 0.019 15.1 1.7 0.019 15.1 1.7 4.8 5 C2CH-3rd_BIRD-IDD BIRD-IDD transcription factor, third C2HC 0.031 14.8 31.8 0.092 13.3 0.3 5.5 4 zf-C2H2_16 C2H2 zinc finger 0.22 12.3 13.7 4.9 8.0 1.1 3.9 3 C1_4 TFIIH C1-like domain 1.3 10.1 7.0 3.6 8.7 0.0 4.0 4 C2H2_ASCIZ ASCIZ first and second C2H2 zinc finger do 3.7 8.1 27.2 0.4 11.2 7.5 3.6 3 Zn_ribbon_SprT SprT-like zinc ribbon domain 4 8.8 13.6 1.4 10.3 1.6 4.4 4 Fer4_16 4Fe-4S double cluster binding domain Domain annotation for each model (and alignments): >> zf-H2C2_2 Zinc-finger double domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 1.8 1.3 2.4e+03 17 25 .. 423 431 .. 416 432 .. 0.79 2 ! 31.4 0.2 1.2e-10 2.1e-07 1 26 [] 435 460 .. 435 460 .. 0.95 3 ! 31.7 3.8 8.9e-11 1.6e-07 2 26 .] 464 488 .. 463 488 .. 0.95 4 ! 27.4 0.3 2.2e-09 3.9e-06 2 25 .. 492 517 .. 491 518 .. 0.89 5 ! 32.5 2.6 5.1e-11 9.3e-08 2 26 .] 522 546 .. 521 546 .. 0.96 6 ? -3.0 0.7 9.5 1.7e+04 4 11 .. 552 560 .. 550 563 .. 0.67 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 1.3 zf-H2C2_2 17 CpeCgksFk 25 C++C k+++ FUN_001604-T1 423 CDHCQKTYS 431 999999987 PP == domain 2 score: 31.4 bits; conditional E-value: 1.2e-10 zf-H2C2_2 1 aLkrHmrtHtgekpykCpeCgksFks 26 aLk H+r+Htge+py C C sF++ FUN_001604-T1 435 ALKVHLRIHTGERPYSCTICKRSFSQ 460 699*********************86 PP == domain 3 score: 31.7 bits; conditional E-value: 8.9e-11 zf-H2C2_2 2 LkrHmrtHtgekpykCpeCgksFks 26 L++H+r+Htgekp++C++C+ +F++ FUN_001604-T1 464 LESHKRSHTGEKPFECDVCHRRFSH 488 89*********************85 PP == domain 4 score: 27.4 bits; conditional E-value: 2.2e-09 zf-H2C2_2 2 LkrHmrtHtgekpykCp..eCgksFk 25 ++ H+r+Htgekp++C Cgk+F+ FUN_001604-T1 492 VRNHKRIHTGEKPFRCAyrGCGKAFT 517 689**************666*****7 PP == domain 5 score: 32.5 bits; conditional E-value: 5.1e-11 zf-H2C2_2 2 LkrHmrtHtgekpykCpeCgksFks 26 Lk+H r+Htgekp++Cp+C +F++ FUN_001604-T1 522 LKKHNRIHTGEKPFQCPHCLRTFTQ 546 89*********************86 PP == domain 6 score: -3.0 bits; conditional E-value: 9.5 zf-H2C2_2 4 rHmrt.Htg 11 +H+r H + FUN_001604-T1 552 KHVRCkHNK 560 688866865 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.1 0.3 5.5e+02 8 20 .. 191 203 .. 190 204 .. 0.90 2 ! 25.4 1.9 1e-08 1.9e-05 1 23 [] 421 443 .. 421 443 .. 0.98 3 ! 22.5 0.7 8.5e-08 0.00015 1 23 [] 449 471 .. 449 471 .. 0.98 4 ! 16.4 4.6 7.4e-06 0.013 1 23 [] 477 499 .. 477 499 .. 0.98 5 ! 22.6 1.0 7.9e-08 0.00014 1 23 [] 505 529 .. 505 529 .. 0.97 6 ! 6.9 5.3 0.0074 14 1 21 [. 535 555 .. 535 558 .. 0.92 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.3 zf-C2H2 8 ksFsrksnLkrHl 20 k F+ k nL+rH FUN_001604-T1 191 KNFTGKINLTRHV 203 78**********5 PP == domain 2 score: 25.4 bits; conditional E-value: 1e-08 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 y C++C+k++sr+s Lk Hlr+H FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLRIH 443 89********************9 PP == domain 3 score: 22.5 bits; conditional E-value: 8.5e-08 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 y+C++C++sFs++ L++H r+H FUN_001604-T1 449 YSCTICKRSFSQAGGLESHKRSH 471 89********************9 PP == domain 4 score: 16.4 bits; conditional E-value: 7.4e-06 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrtH 23 ++C++C+++Fs+++ ++H r+H FUN_001604-T1 477 FECDVCHRRFSHSTAVRNHKRIH 499 89********************9 PP == domain 5 score: 22.6 bits; conditional E-value: 7.9e-08 zf-C2H2 1 ykCp..dCgksFsrksnLkrHlrtH 23 ++C +Cgk+F+++s+Lk+H r+H FUN_001604-T1 505 FRCAyrGCGKAFTDQSTLKKHNRIH 529 899999*****************99 PP == domain 6 score: 6.9 bits; conditional E-value: 0.0074 zf-C2H2 1 ykCpdCgksFsrksnLkrHlr 21 ++Cp+C ++F++ n ++H r FUN_001604-T1 535 FQCPHCLRTFTQLGNKNKHVR 555 8*************9999987 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 9.1 1.7e+04 6 19 .. 149 163 .. 146 166 .. 0.71 2 ? -1.8 0.1 6.2 1.1e+04 8 20 .. 191 203 .. 190 205 .. 0.83 3 ! 19.2 1.3 1e-06 0.0019 1 23 [. 421 443 .. 421 444 .. 0.95 4 ! 18.1 0.6 2.4e-06 0.0043 1 23 [. 449 471 .. 449 472 .. 0.95 5 ! 13.1 3.5 9.6e-05 0.18 1 23 [. 477 499 .. 477 500 .. 0.95 6 ! 7.8 0.5 0.0049 8.9 1 19 [. 505 525 .. 505 529 .. 0.86 7 ! 9.4 4.1 0.0015 2.8 1 21 [. 535 555 .. 535 558 .. 0.93 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 9.1 zf-C2H2_4 6 CgksFsskka.LrrH 19 C+ +++ + L++H FUN_001604-T1 149 CKNAVNTNAQvLQNH 163 766667777768889 PP == domain 2 score: -1.8 bits; conditional E-value: 6.2 zf-C2H2_4 8 ksFsskkaLrrHl 20 k F+ k +L rH+ FUN_001604-T1 191 KNFTGKINLTRHV 203 67889999****7 PP == domain 3 score: 19.2 bits; conditional E-value: 1e-06 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 + C++C+k++s+++aL+ Hl+ h FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLRIH 443 89*******************99 PP == domain 4 score: 18.1 bits; conditional E-value: 2.4e-06 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 + C+iC++sFs +L +H ++h FUN_001604-T1 449 YSCTICKRSFSQAGGLESHKRSH 471 79********************9 PP == domain 5 score: 13.1 bits; conditional E-value: 9.6e-05 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkkh 23 f+C++C+++Fs ++a r+H + h FUN_001604-T1 477 FECDVCHRRFSHSTAVRNHKRIH 499 89******************999 PP == domain 6 score: 7.8 bits; conditional E-value: 0.0049 zf-C2H2_4 1 fkCpi..CgksFsskkaLrrH 19 f+C + Cgk F+++++L++H FUN_001604-T1 505 FRCAYrgCGKAFTDQSTLKKH 525 6777777************** PP == domain 7 score: 9.4 bits; conditional E-value: 0.0015 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlk 21 f+Cp+C ++F+ + ++H++ FUN_001604-T1 535 FQCPHCLRTFTQLGNKNKHVR 555 8*************9999*86 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.2 2.4 4.4e+03 13 20 .. 156 163 .. 155 163 .. 0.91 2 ! 14.4 2.2 2.5e-05 0.046 2 22 .. 421 441 .. 420 441 .. 0.94 3 ! 10.9 0.1 0.00031 0.56 2 23 .. 449 470 .. 448 471 .. 0.94 4 ! 12.8 0.4 8e-05 0.15 1 22 [. 476 497 .. 476 497 .. 0.94 5 ? 4.4 0.1 0.035 65 7 20 .. 512 525 .. 512 527 .. 0.94 6 ? 0.2 0.1 0.74 1.3e+03 2 11 .. 535 544 .. 534 555 .. 0.82 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.4 zf-C2H2_jaz 13 senalqnH 20 ++++lqnH FUN_001604-T1 156 NAQVLQNH 163 899***** PP == domain 2 score: 14.4 bits; conditional E-value: 2.5e-05 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlk 22 + C +C+K+++ ++al+ Hl+ FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLR 441 78*****************96 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00031 zf-C2H2_jaz 2 fYCvlCdKyFksenalqnHlkS 23 + C++C++ F+ + l+ H++S FUN_001604-T1 449 YSCTICKRSFSQAGGLESHKRS 470 89******************99 PP == domain 4 score: 12.8 bits; conditional E-value: 8e-05 zf-C2H2_jaz 1 qfYCvlCdKyFksenalqnHlk 22 +f+C +C + F+ + a +nH++ FUN_001604-T1 476 PFECDVCHRRFSHSTAVRNHKR 497 59******************86 PP == domain 5 score: 4.4 bits; conditional E-value: 0.035 zf-C2H2_jaz 7 CdKyFksenalqnH 20 C K F ++++l+ H FUN_001604-T1 512 CGKAFTDQSTLKKH 525 9************* PP == domain 6 score: 0.2 bits; conditional E-value: 0.74 zf-C2H2_jaz 2 fYCvlCdKyF 11 f C++C ++F FUN_001604-T1 535 FQCPHCLRTF 544 67****8888 PP >> zf-C2H2_15 C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.3 0.00019 0.35 6 30 .] 423 447 .. 422 447 .. 0.81 2 ! 6.3 0.0 0.0073 13 22 30 .] 467 475 .. 451 475 .. 0.89 3 ! 7.2 1.1 0.0038 6.9 21 30 .] 494 503 .. 479 503 .. 0.94 4 ! 9.7 0.2 0.00066 1.2 4 30 .] 510 533 .. 507 533 .. 0.83 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00019 zf-C2H2_15 6 CsRegkpFkAkYkLvvHiRvHTgEK 30 C+ +k + + L vH+R HTgE+ FUN_001604-T1 423 CDHCQKTYSRQSALKVHLRIHTGER 447 666677777777899*********7 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0073 zf-C2H2_15 22 HiRvHTgEK 30 H R HTgEK FUN_001604-T1 467 HKRSHTGEK 475 99******9 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0038 zf-C2H2_15 21 vHiRvHTgEK 30 +H R HTgEK FUN_001604-T1 494 NHKRIHTGEK 503 8********9 PP == domain 4 score: 9.7 bits; conditional E-value: 0.00066 zf-C2H2_15 4 eeCsRegkpFkAkYkLvvHiRvHTgEK 30 ++C gk F + L H R HTgEK FUN_001604-T1 510 RGC---GKAFTDQSTLKKHNRIHTGEK 533 555...789999999999********9 PP >> zf-met Zinc-finger of C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 1.3 2.3e-05 0.043 1 21 [. 421 441 .. 421 444 .. 0.93 2 ! 12.5 0.8 0.00011 0.21 1 23 [. 449 471 .. 449 472 .. 0.95 3 ! 11.8 1.1 0.00018 0.34 1 21 [. 477 497 .. 477 500 .. 0.92 4 ? 6.3 0.1 0.01 19 6 21 .. 512 527 .. 511 530 .. 0.91 5 ? 2.8 0.3 0.12 2.3e+02 1 15 [. 535 549 .. 535 555 .. 0.75 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 2.3e-05 zf-met 1 fyCelCnvtftsesqlksHlq 21 + C+ C++t+ ++s+lk Hl+ FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLR 441 79******************8 PP == domain 2 score: 12.5 bits; conditional E-value: 0.00011 zf-met 1 fyCelCnvtftsesqlksHlqGK 23 + C +C+++f l+sH +++ FUN_001604-T1 449 YSCTICKRSFSQAGGLESHKRSH 471 89*******************98 PP == domain 3 score: 11.8 bits; conditional E-value: 0.00018 zf-met 1 fyCelCnvtftsesqlksHlq 21 f+C++C+++f + ++ ++H + FUN_001604-T1 477 FECDVCHRRFSHSTAVRNHKR 497 89*****************87 PP == domain 4 score: 6.3 bits; conditional E-value: 0.01 zf-met 6 CnvtftsesqlksHlq 21 C + ft++s+lk H + FUN_001604-T1 512 CGKAFTDQSTLKKHNR 527 99************76 PP == domain 5 score: 2.8 bits; conditional E-value: 0.12 zf-met 1 fyCelCnvtftsesq 15 f C+ C +tft + FUN_001604-T1 535 FQCPHCLRTFTQLGN 549 78********95555 PP >> zf-C2H2_6 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 2.3 0.00066 1.2 2 24 .. 421 443 .. 420 446 .. 0.92 2 ! 17.3 1.4 2.8e-06 0.005 2 24 .. 449 471 .. 449 474 .. 0.93 3 ! 14.7 1.5 1.8e-05 0.033 2 24 .. 477 499 .. 477 502 .. 0.93 4 ? 0.9 0.4 0.37 6.8e+02 7 24 .. 512 529 .. 505 532 .. 0.85 5 ? -1.3 2.6 1.9 3.5e+03 2 13 .. 535 546 .. 535 560 .. 0.77 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00066 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksH 24 ++C+ C k++s++ aL H++ H FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLRIH 443 89*****************9877 PP == domain 2 score: 17.3 bits; conditional E-value: 2.8e-06 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksH 24 + C++C++sFs L+ Hk+sH FUN_001604-T1 449 YSCTICKRSFSQAGGLESHKRSH 471 77********************* PP == domain 3 score: 14.7 bits; conditional E-value: 1.8e-05 zf-C2H2_6 2 feCsvCgksFssyqaLggHkksH 24 feC+vC+++Fs +a + Hk+ H FUN_001604-T1 477 FECDVCHRRFSHSTAVRNHKRIH 499 9*******************977 PP == domain 4 score: 0.9 bits; conditional E-value: 0.37 zf-C2H2_6 7 CgksFssyqaLggHkksH 24 Cgk F + L +H++ H FUN_001604-T1 512 CGKAFTDQSTLKKHNRIH 529 ******999999999877 PP == domain 5 score: -1.3 bits; conditional E-value: 1.9 zf-C2H2_6 2 feCsvCgksFss 13 f C+ C ++F FUN_001604-T1 535 FQCPHCLRTFTQ 546 77********75 PP >> zf-C2HC_2 zinc-finger of a C2HC-type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 3.3 6.1e+03 10 18 .. 54 63 .. 53 63 .. 0.84 2 ? 5.4 0.1 0.012 22 4 23 .. 422 442 .. 421 442 .. 0.94 3 ! 6.1 0.2 0.0073 13 5 13 .. 451 459 .. 449 470 .. 0.79 4 ? 4.3 2.4 0.027 50 4 23 .. 478 498 .. 477 498 .. 0.89 5 ? 1.2 0.1 0.25 4.6e+02 7 23 .. 511 528 .. 510 528 .. 0.87 6 ! 10.5 0.3 0.00031 0.56 4 12 .. 536 544 .. 535 547 .. 0.89 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 3.3 zf-C2HC_2 10 RkF.npdrLe 18 R+F np++++ FUN_001604-T1 54 RTFtNPSSCA 63 99*9999975 PP == domain 2 score: 5.4 bits; conditional E-value: 0.012 zf-C2HC_2 4 pCpiCGRkF.npdrLekHekv 23 C +C ++ +++L++H+++ FUN_001604-T1 422 ICDHCQKTYsRQSALKVHLRI 442 5*****************986 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0073 zf-C2HC_2 5 CpiCGRkFn 13 C iC R+F FUN_001604-T1 451 CTICKRSFS 459 ********4 PP == domain 4 score: 4.3 bits; conditional E-value: 0.027 zf-C2HC_2 4 pCpiCGRkF.npdrLekHekv 23 +C C R+F + ++ H+++ FUN_001604-T1 478 ECDVCHRRFsHSTAVRNHKRI 498 7********999999999876 PP == domain 5 score: 1.2 bits; conditional E-value: 0.25 zf-C2HC_2 7 iCGRkF.npdrLekHekv 23 CG F ++ L+kH ++ FUN_001604-T1 511 GCGKAFtDQSTLKKHNRI 528 6*****99*******775 PP == domain 6 score: 10.5 bits; conditional E-value: 0.00031 zf-C2HC_2 4 pCpiCGRkF 12 +Cp+C R+F FUN_001604-T1 536 QCPHCLRTF 544 8******** PP >> C2CH-3rd_BIRD-IDD BIRD-IDD transcription factor, third C2HC zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 1.7 1e-05 0.019 2 23 .. 421 442 .. 420 442 .. 0.94 2 ? -1.4 0.4 1.5 2.8e+03 1 11 [. 448 458 .. 448 459 .. 0.86 3 ? 2.4 0.1 0.097 1.8e+02 1 11 [. 476 486 .. 476 493 .. 0.90 4 ? 1.6 0.0 0.17 3.2e+02 5 23 .. 510 528 .. 504 528 .. 0.78 5 ? 1.9 0.0 0.14 2.6e+02 1 11 [. 534 544 .. 534 545 .. 0.86 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1e-05 C2CH-3rd_BIRD-IDD 2 wkCekCsKsYAVeSDwKAHlKt 23 + C++C K+Y +S +K Hl++ FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLRI 442 67******************97 PP == domain 2 score: -1.4 bits; conditional E-value: 1.5 C2CH-3rd_BIRD-IDD 1 kwkCekCsKsY 11 +++C C +s+ FUN_001604-T1 448 PYSCTICKRSF 458 689****9986 PP == domain 3 score: 2.4 bits; conditional E-value: 0.097 C2CH-3rd_BIRD-IDD 1 kwkCekCsKsY 11 +++C+ C +++ FUN_001604-T1 476 PFECDVCHRRF 486 69*****9987 PP == domain 4 score: 1.6 bits; conditional E-value: 0.17 C2CH-3rd_BIRD-IDD 5 ekCsKsYAVeSDwKAHlKt 23 + C+K++ +S +K H ++ FUN_001604-T1 510 RGCGKAFTDQSTLKKHNRI 528 47*****999999999886 PP == domain 5 score: 1.9 bits; conditional E-value: 0.14 C2CH-3rd_BIRD-IDD 1 kwkCekCsKsY 11 +++C++C +++ FUN_001604-T1 534 PFQCPHCLRTF 544 69*****9876 PP >> zf-C2H2_16 C2H2 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 3.1 0.00038 0.7 4 26 .] 421 446 .. 419 446 .. 0.69 2 ? 6.2 0.4 0.0085 15 1 26 [] 449 474 .. 449 474 .. 0.86 3 ? 5.3 0.2 0.016 29 19 26 .] 495 502 .. 489 502 .. 0.92 4 ? 13.3 0.3 5e-05 0.092 9 26 .] 515 532 .. 507 532 .. 0.87 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00038 zf-C2H2_16 4 pfCdyack...drlrLeyHvriHtGe 26 Cd k +++ L+ H riHtGe FUN_001604-T1 421 YICDHCQKtysRQSALKVHLRIHTGE 446 455544332228999**********8 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0085 zf-C2H2_16 1 ykCpfCdyackdrlrLeyHvriHtGe 26 y C+ C + + Le H r HtGe FUN_001604-T1 449 YSCTICKRSFSQAGGLESHKRSHTGE 474 7788888888888889*********8 PP == domain 3 score: 5.3 bits; conditional E-value: 0.016 zf-C2H2_16 19 HvriHtGe 26 H riHtGe FUN_001604-T1 495 HKRIHTGE 502 *******8 PP == domain 4 score: 13.3 bits; conditional E-value: 5e-05 zf-C2H2_16 9 ackdrlrLeyHvriHtGe 26 a +d++ L+ H riHtGe FUN_001604-T1 515 AFTDQSTLKKHNRIHTGE 532 5589*************8 PP >> C1_4 TFIIH C1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.3 0.0052 9.5 11 48 .. 406 443 .. 400 446 .. 0.73 2 ? 8.0 1.1 0.0027 4.9 1 48 [. 450 499 .. 448 502 .. 0.77 3 ? 3.9 1.0 0.05 91 4 35 .. 511 544 .. 506 546 .. 0.74 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0052 C1_4 11 klakkkkdeeltssryrCekCkqdFCiDCDvFiHesLH 48 ++++++ d + s +y C++C++++ + +H +H FUN_001604-T1 406 EAISQSLDGKKGSKCYICDHCQKTYSRQSALKVHLRIH 443 5556666777899**********997666666665555 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0027 C1_4 1 eCfgCqkkfpkla..kkkkdeeltssryrCekCkqdFCiDCDvFiHesLH 48 +C C+++f ++ +++k +++ + ++C+ C++ F v H +H FUN_001604-T1 450 SCTICKRSFSQAGglESHKRSHTGEKPFECDVCHRRFSHSTAVRNHKRIH 499 5999***99987511455555688999**********8777777777777 PP == domain 3 score: 3.9 bits; conditional E-value: 0.05 C1_4 4 gCqkkfpklakkkkdee..ltssryrCekCkqdF 35 gC k+f+ + + kk+++ + + ++C++C ++F FUN_001604-T1 511 GCGKAFTDQSTLKKHNRihTGEKPFQCPHCLRTF 544 899999876655444443477899******9888 PP >> C2H2_ASCIZ ASCIZ first and second C2H2 zinc finger domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.27 5e+02 9 27 .. 426 440 .. 421 443 .. 0.89 2 ? -1.5 0.0 2.9 5.3e+03 2 26 .. 449 467 .. 449 468 .. 0.77 3 ? -0.2 0.2 1.2 2.1e+03 9 26 .. 482 495 .. 479 496 .. 0.89 4 ? 8.7 0.0 0.002 3.6 4 26 .. 507 525 .. 505 526 .. 0.95 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.27 C2H2_ASCIZ 9 CPRGPgkilsqfsllkqHl 27 C k +s s+lk Hl FUN_001604-T1 426 C----QKTYSRQSALKVHL 440 5....8999*********8 PP == domain 2 score: -1.5 bits; conditional E-value: 2.9 C2H2_ASCIZ 2 ilCtvrGCPRGPgkilsqfsllkqH 26 + Ct+ C + +sq l H FUN_001604-T1 449 YSCTI--C----KRSFSQAGGLESH 467 66888..8....8999998777666 PP == domain 3 score: -0.2 bits; conditional E-value: 1.2 C2H2_ASCIZ 9 CPRGPgkilsqfsllkqH 26 C + +s + +++ H FUN_001604-T1 482 C----HRRFSHSTAVRNH 495 5....799*******999 PP == domain 4 score: 8.7 bits; conditional E-value: 0.002 C2H2_ASCIZ 4 CtvrGCPRGPgkilsqfsllkqH 26 C rGC gk + + s lk H FUN_001604-T1 507 CAYRGC----GKAFTDQSTLKKH 525 999***....************9 PP >> Zn_ribbon_SprT SprT-like zinc ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 7.5 0.00022 0.4 5 36 .. 421 460 .. 420 462 .. 0.93 2 ? -0.3 3.7 0.88 1.6e+03 7 27 .. 479 507 .. 478 509 .. 0.89 3 ? 7.8 1.1 0.0025 4.6 9 36 .. 511 546 .. 510 548 .. 0.93 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00022 Zn_ribbon_SprT 5 YvCpgCgreytrhrrvrrhn........yrCrrCkgtLkg 36 Y+C +C+++y+r++ ++h y C Ck +++ FUN_001604-T1 421 YICDHCQKTYSRQSALKVHLrihtgerpYSCTICKRSFSQ 460 9******************99**************87665 PP == domain 2 score: -0.3 bits; conditional E-value: 0.88 Zn_ribbon_SprT 7 CpgCgreytrhrrvrrhn........yrC 27 C +C+r++++ vr h+ +rC FUN_001604-T1 479 CDVCHRRFSHSTAVRNHKrihtgekpFRC 507 778************99999999999999 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0025 Zn_ribbon_SprT 9 gCgreytrhrrvrrhn........yrCrrCkgtLkg 36 gCg+ +t +++ + hn + C++C t+++ FUN_001604-T1 511 GCGKAFTDQSTLKKHNrihtgekpFQCPHCLRTFTQ 546 7*****************************888876 PP >> Fer4_16 4Fe-4S double cluster binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 1.6 0.00074 1.4 29 61 .. 396 428 .. 379 429 .. 0.76 2 ? 1.7 0.1 0.35 6.4e+02 42 60 .. 437 455 .. 428 457 .. 0.75 3 ? 1.9 0.1 0.31 5.7e+02 43 60 .. 466 483 .. 457 485 .. 0.79 4 ? 0.0 0.2 1.2 2.1e+03 27 60 .. 510 541 .. 495 543 .. 0.64 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00074 Fer4_16 29 cisyltiekkkliedeerkkegnriygCdiCqe 61 ++++ ++ +++i + k+g+++y Cd Cq+ FUN_001604-T1 396 QEDNEVAKSNEAISQSLDGKKGSKCYICDHCQK 428 334467889999999999999**********97 PP == domain 2 score: 1.7 bits; conditional E-value: 0.35 Fer4_16 42 edeerkkegnriygCdiCq 60 + r + g+r y C+iC FUN_001604-T1 437 KVHLRIHTGERPYSCTICK 455 556677889999******7 PP == domain 3 score: 1.9 bits; conditional E-value: 0.31 Fer4_16 43 deerkkegnriygCdiCq 60 +r++ g++ + Cd+C FUN_001604-T1 466 SHKRSHTGEKPFECDVCH 483 45667779999******6 PP == domain 4 score: 0.0 bits; conditional E-value: 1.2 Fer4_16 27 rkcisyltiekkkliedeerkkegnriygCdiCq 60 r c ++ ++ ++ +r + g++ + C C FUN_001604-T1 510 RGCGKA--FTDQSTLKKHNRIHTGEKPFQCPHCL 541 455544..23334455666777799999999996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (564 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1062 (0.0415737); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.43 # Mc/sec: 5234.43 // Query: FUN_001605-T1 [L=1205] Description: FUN_001605 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-15 55.6 0.0 2.1e-14 54.1 0.0 1.8 1 TUDOR Tudor domain Domain annotation for each model (and alignments): >> TUDOR Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.1 0.0 8.2e-19 2.1e-14 5 114 .. 53 166 .. 51 173 .. 0.85 Alignments for each domain: == domain 1 score: 54.1 bits; conditional E-value: 8.2e-19 TUDOR 5 etidvvvseiespstfyi..qpkesskkleklteelqeyykskpk..eslkpkvgegcvavfsedgkwyRAkiteslddqkveVlfiDyGntetvp 96 +++ v v++i + +f++ + ++ k++++ + +l+ +++++k + + p+ g+ ++++ ++ +w+RA++ l+d++++V+++DyG++e+v+ FUN_001605-T1 53 NDSHVRVTHIIDVEHFWAqiGSLDELKEFDRYMLSLNVWCNEQQKsgDLQIPQFGQPVCVRHKDTSQWRRAQV-TRLSDDMIDVFYLDYGQSECVS 147 57789*************777888999*******************66666777777777777777*******.********************** PP TUDOR 97 lsdlrelp.eeleslppqa 114 l+++++ ++ s + +a FUN_001605-T1 148 LDRICHSTpGDILSRRAMA 166 ****998755665555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1205 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1297 (0.0507731); expected 510.9 (0.02) Passed bias filter: 657 (0.0257193); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.47u 0.38s 00:00:00.85 Elapsed: 00:00:00.43 # Mc/sec: 11420.39 // Query: FUN_001605-T2 [L=1010] Description: FUN_001605 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1010 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1448 (0.0566843); expected 510.9 (0.02) Passed bias filter: 681 (0.0266588); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.43u 0.42s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 9590.47 // Query: FUN_001605-T3 [L=1074] Description: FUN_001605 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.06 13.9 0.0 0.18 12.4 0.0 1.9 1 TUDOR Tudor domain Domain annotation for each model (and alignments): >> TUDOR Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 7e-06 0.18 82 114 .. 2 35 .. 1 42 [. 0.77 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7e-06 TUDOR 82 veVlfiDyGntetvplsdlrelp.eeleslppqa 114 ++V+++DyG++e+v+l+++++ ++ s + +a FUN_001605-T3 2 IDVFYLDYGQSECVSLDRICHSTpGDILSRRAMA 35 79*****************998755665555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1074 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1565 (0.0612644); expected 510.9 (0.02) Passed bias filter: 766 (0.0299863); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.50u 0.37s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 9958.46 // Query: FUN_001605-T4 [L=830] Description: FUN_001605 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-15 56.3 0.0 1.3e-14 54.8 0.0 1.8 1 TUDOR Tudor domain ------ inclusion threshold ------ 0.25 11.4 0.1 0.55 10.3 0.1 1.6 1 Dis32-like_C DIS3-like exonuclease 2-like, C-terminal Domain annotation for each model (and alignments): >> TUDOR Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.8 0.0 9.8e-19 1.3e-14 5 114 .. 53 166 .. 51 173 .. 0.85 Alignments for each domain: == domain 1 score: 54.8 bits; conditional E-value: 9.8e-19 TUDOR 5 etidvvvseiespstfyi..qpkesskkleklteelqeyykskpk..eslkpkvgegcvavfsedgkwyRAkiteslddqkveVlfiDyGntetvp 96 +++ v v++i + +f++ + ++ k++++ + +l+ +++++k + + p+ g+ ++++ ++ +w+RA++ l+d++++V+++DyG++e+v+ FUN_001605-T4 53 NDSHVRVTHIIDVEHFWAqiGSLDELKEFDRYMLSLNVWCNEQQKsgDLQIPQFGQPVCVRHKDTSQWRRAQV-TRLSDDMIDVFYLDYGQSECVS 147 57789*************777888999*******************66666777777777777777*******.********************** PP TUDOR 97 lsdlrelp.eeleslppqa 114 l+++++ ++ s + +a FUN_001605-T4 148 LDRICHSTpGDILSRRAMA 166 ****998755665555555 PP >> Dis32-like_C DIS3-like exonuclease 2-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.1 4.3e-05 0.55 8 31 .. 125 148 .. 122 149 .. 0.88 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 4.3e-05 Dis32-like_C 8 ATRIsdrSIDVYvSeYGISsRVDL 31 TR sd IDV+ +YG S V L FUN_001605-T4 125 VTRLSDDMIDVFYLDYGQSECVSL 148 6****************9988865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (830 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 998 (0.0390683); expected 510.9 (0.02) Passed bias filter: 692 (0.0270894); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.41s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 7873.92 // Query: FUN_001608-T1 [L=423] Description: FUN_001608 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-48 165.1 23.1 9.5e-43 146.9 25.9 2.0 2 MFS_1 Major Facilitator Superfamily 6.1e-12 45.6 9.1 1.9e-05 24.2 0.0 2.1 2 Sugar_tr Sugar (and other) transporter ------ inclusion threshold ------ 0.25 12.2 0.3 11 7.0 0.0 2.7 2 DUF4179 Domain of unknown function (DUF4179) 0.81 10.4 5.0 0.92 10.2 0.0 3.2 4 Anthrone_oxy Anthrone oxygenase Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 146.9 25.9 1.5e-46 9.5e-43 48 347 .] 1 322 [. 1 322 [. 0.86 2 ! 13.6 0.0 5.1e-06 0.032 147 173 .. 334 361 .. 324 402 .. 0.74 Alignments for each domain: == domain 1 score: 146.9 bits; conditional E-value: 1.5e-46 MFS_1 48 aqllaGrlsdrfGrrrvlllglllfalglllll.fa..sslwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpll 140 +q+++G+l++rfG rv+ ++l+++++ ++l+ +a +s+ +l+ lrv+ Gl+ galfp+ +a+ ++w+p++er+r + + ag ++G++l ++l FUN_001608-T1 1 MQIPGGWLGQRFGGTRVFGICLGIASVL-TMLTpLAarTSVAALITLRVIEGLALGALFPCNHAIWSKWAPPTERTRLFTITVAGCPVGTILSMPL 95 699*************************.7777665578888****************************************************** PP MFS_1 141 ggllaslfg....wravFlilailallaavlaalllprpppeskrkkpaee............apapllp....awkallrdpvlw.lllalllfg 215 +g+++ +g w +vF+ +++++ll+++++ l + +p+++++ + +e+ a + wk++l + ++w +++a +++ FUN_001608-T1 96 SGVMS-KYGfdggWASVFYCFGAIGLLWFFVWQLAIHGSPSDHPTITTEERdyieesiaqlppA-----KkgqvPWKSILLSGPVWaIITANFTAD 185 ****9.5555899**********************************9999**88888655444.....245566********************* PP MFS_1 216 laffalltllply.qevlglsglllaglllglaallgaigrlllgrlsdr.....lgr.rrrlllallllllaalgllllsltesslwlllallll 304 ++++++l+ lp y +evl+++ l +g+l +l+ ++ ++++ +g l+d+ ++ ++r ++ +++ +a++++l+++++ s++++++a+l + FUN_001608-T1 186 WGMYTILICLPKYfIEVLHFD-LAKTGFLAALPYVVKTFVGPSGGVLVDWliknhMSVkNTRRCVFTVGCTTASIFILITGYA-STPAMAVAFLTI 279 *********************.7777777777777777777777777777555553332455555555555555555566666.78888889**** PP MFS_1 305 Gf.gfglvfplllalvsdlapkeergtasglyntagslggalgp 347 G+ gl + +++ + d ap +++g ++g+ n++gs g+++p FUN_001608-T1 280 GVgITGLNASGYAVNILDIAP-QYAGVIMGVTNVFGSAPGFISP 322 **8888889999999999998.*******************998 PP == domain 2 score: 13.6 bits; conditional E-value: 5.1e-06 MFS_1 147 lfgwravFlilailallaavlaalll.p 173 ++ wr vF+i+a+++++++v++ ll+ FUN_001608-T1 334 AGEWRIVFWITAVVYVIGIVIFGLLVsG 361 456*****************76666641 PP >> Sugar_tr Sugar (and other) transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 8.9 7.4e-08 0.00047 66 188 .. 5 126 .. 2 135 .. 0.91 2 ! 24.2 0.0 3e-09 1.9e-05 74 237 .. 245 407 .. 209 417 .. 0.78 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 7.4e-08 Sugar_tr 66 agllgdrfGRkkslliaivlfvigavlqaaakgkksvellivgRvlvGigvGlasvlvPlyisEiApkklRgalvslyqlaitfGillaaiiglgl 161 g+lg+rfG ++ i++ ++++ ++l+ +a ++sv +li Rv+ G+++G+ + s Ap++ R +l +++ ++ +G++l+ + + FUN_001608-T1 5 GGWLGQRFGGTRVFGICLGIASVLTMLTPLAA-RTSVAALITLRVIEGLALGALFPCNHAIWSKWAPPTERTRLFTITVAGCPVGTILSMPLSGVM 99 69************999999999999999999.56*******************************************************999999 PP Sugar_tr 162 kktsnsdgWrillglqlvpallllill 188 +k++ + gW ++ +++ll ++++ FUN_001608-T1 100 SKYGFDGGWASVFYCFGAIGLLWFFVW 126 888888******999999998887776 PP == domain 2 score: 24.2 bits; conditional E-value: 3e-09 Sugar_tr 74 GRkkslliaivlfvigavlqaaakgkksvellivgRvlvGigv.GlasvlvPlyisEiApkklRgalvslyqlaitfGillaaiiglgl.kktsns 167 R+ ++ +++ ++i++++++ a + +++v+ + +G+g+ Gl + i iAp+ ++++ + ++ + G++ +i+g + +kt + FUN_001608-T1 245 TRRCVFTVGCTTASIFILITGYAS----TPAMAVAFLTIGVGItGLNASGYAVNILDIAPQYAGVIMGVTNVFGSAPGFISPQIVGILTpNKTAG- 335 578888888889999999998888....5555665556666642566677788899*********************************988888. PP Sugar_tr 168 dgWrillglqlvpall..llilllflPESPrwlvekgkee.eAkevlaklrgeedvdeelkeikdsleaeqee 237 Wri +++++v ++ ++++ll+ E w ++++++ +ke + +ee++ e l+e+k+ e+ +e FUN_001608-T1 336 -EWRIVFWITAVVYVIgiVIFGLLVSGELQPWAESNKDDDkGDKEDKNDGGDEEKAAETLDEEKKDKEKPEEG 407 .9********999876215667788889999998777777356666666777788899999998888776554 PP >> DUF4179 Domain of unknown function (DUF4179) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 1.0 0.089 5.7e+02 22 34 .. 264 276 .. 245 313 .. 0.58 2 ? 7.0 0.0 0.0017 11 7 71 .. 340 401 .. 337 403 .. 0.80 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.089 DUF4179 22 gsvlvspafaeyv 34 ++ +pa+a + FUN_001608-T1 264 TGYASTPAMAVAF 276 5555555555222 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0017 DUF4179 7 kkiaaaaaalialllgsvlvspafaeyvkeipiigsifellsddkglkaa...eeeysqeinksvtdn 71 + +++a++ +i++++++ lvs + p+ +s + ++dk++k++ ee+ ++++++ ++d+ FUN_001608-T1 340 VFWITAVVYVIGIVIFGLLVSGELQ------PWAESNKDDDKGDKEDKNDggdEEKAAETLDEEKKDK 401 457888888899989**********......7777776666666666666777**********99998 PP >> Anthrone_oxy Anthrone oxygenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.5 0.18 1.1e+03 12 67 .. 13 66 .. 7 91 .. 0.61 2 ? -3.4 0.2 2.5 1.6e+04 1 27 [. 108 129 .. 108 138 .. 0.59 3 ? -1.7 0.2 0.72 4.6e+03 53 55 .. 263 265 .. 218 287 .. 0.58 4 ? 10.2 0.0 0.00014 0.92 29 72 .. 330 380 .. 302 413 .. 0.64 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.18 Anthrone_oxy 12 fpalalaaalaylylarrarrsaaarlllaaAallllgivpfTllvmvplNnaLaa 67 ++ +++++l+++ + + ++ aar +a A++ l +i + l ++ p N a+ + FUN_001608-T1 13 GGTRVFGICLGIA-SVLTMLTPLAARTSVA-ALITLRVIEGLALGALFPCNHAIWS 66 4554555555555.3333444555555545.6777777777777777777766544 PP == domain 2 score: -3.4 bits; conditional E-value: 2.5 Anthrone_oxy 1 wallfkrgkavfpalalaaalaylyla 27 wa +f + f+a+ l+ +++++ la FUN_001608-T1 108 WASVF----YCFGAIGLLWFFVWQ-LA 129 66666....667776666666666.33 PP == domain 3 score: -1.7 bits; conditional E-value: 0.72 Anthrone_oxy 53 fTl 55 +T FUN_001608-T1 263 ITG 265 222 PP == domain 4 score: 10.2 bits; conditional E-value: 0.00014 Anthrone_oxy 29 rarrsaaarlllaaAal.lllgivpfTllvmvplN.....naLaal.keaa 72 ++++ +r+++ ++a+ +++giv+f llv l n+ + + ++++ FUN_001608-T1 330 PNKTAGEWRIVFWITAVvYVIGIVIFGLLVSGELQpwaesNKDDDKgDKED 380 455666666665555555*************99884433322222231222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (423 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1793 (0.0701899); expected 510.9 (0.02) Passed bias filter: 965 (0.0377765); expected 510.9 (0.02) Passed Vit filter: 132 (0.00516735); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.40u 0.37s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 4108.71 // Query: FUN_001608-T2 [L=522] Description: FUN_001608 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-54 184.9 25.6 7.5e-49 167.0 28.4 2.1 2 MFS_1 Major Facilitator Superfamily 1.1e-13 51.4 12.6 5.2e-06 26.1 12.3 2.2 2 Sugar_tr Sugar (and other) transporter ------ inclusion threshold ------ 0.65 10.9 1.6 15 6.5 0.0 3.1 3 DUF4179 Domain of unknown function (DUF4179) 1.3 9.7 0.0 1.3 9.7 0.0 3.4 5 Anthrone_oxy Anthrone oxygenase Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 167.0 28.4 1.2e-52 7.5e-49 2 347 .] 40 421 .. 36 421 .. 0.85 2 ! 13.2 0.0 6.7e-06 0.043 147 173 .. 433 460 .. 423 501 .. 0.74 Alignments for each domain: == domain 1 score: 167.0 bits; conditional E-value: 1.2e-52 MFS_1 2 llaaflaalgrsllgpalplll...............aedlgispseigllltlfslgyalaqllaGrlsdrfGrrrvlllglllfalglllll.f 81 +l++++ ++ r +l++a+ ++ + ++ +s+ + g +l++f+ gy ++q+++G+l++rfG rv+ ++l+++++ ++l+ + FUN_001608-T2 40 FLGICVQYALRVNLSVAIG-AMcnnhtieqngftihkKAEFDWSSKLQGTILGAFYYGYTAMQIPGGWLGQRFGGTRVFGICLGIASVL-TMLTpL 133 7777778888888888887.5656666666666666677899***********************************************.777766 PP MFS_1 82 a..sslwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfg....wravFlilailallaavlaall 171 a +s+ +l+ lrv+ Gl+ galfp+ +a+ ++w+p++er+r + + ag ++G++l ++l+g+++ +g w +vF+ +++++ll+++++ l FUN_001608-T2 134 AarTSVAALITLRVIEGLALGALFPCNHAIWSKWAPPTERTRLFTITVAGCPVGTILSMPLSGVMS-KYGfdggWASVFYCFGAIGLLWFFVWQLA 228 5578888**********************************************************9.5555899********************** PP MFS_1 172 lprpppeskrkkpaee............apapllp....awkallrdpvlw.lllalllfglaffalltllply.qevlglsglllaglllglaal 249 + +p+++++ + +e+ a + wk++l + ++w +++a +++ ++++++l+ lp y +evl+++ l +g+l +l+ + FUN_001608-T2 229 IHGSPSDHPTITTEERdyieesiaqlppA-----KkgqvPWKSILLSGPVWaIITANFTADWGMYTILICLPKYfIEVLHFD-LAKTGFLAALPYV 318 ************9999**88888655444.....245566******************************************.7777777777777 PP MFS_1 250 lgaigrlllgrlsdr.....lgr.rrrlllallllllaalgllllsltesslwlllallllGf.gfglvfplllalvsdlapkeergtasglynta 338 + ++++ +g l+d+ ++ ++r ++ +++ +a++++l+++++ s++++++a+l +G+ gl + +++ + d ap +++g ++g+ n++ FUN_001608-T2 319 VKTFVGPSGGVLVDWliknhMSVkNTRRCVFTVGCTTASIFILITGYA-STPAMAVAFLTIGVgITGLNASGYAVNILDIAP-QYAGVIMGVTNVF 412 777777777777777555553332455555555555555555566666.78888889******8888889999999999998.************* PP MFS_1 339 gslggalgp 347 gs g+++p FUN_001608-T2 413 GSAPGFISP 421 ******998 PP == domain 2 score: 13.2 bits; conditional E-value: 6.7e-06 MFS_1 147 lfgwravFlilailallaavlaalll.p 173 ++ wr vF+i+a+++++++v++ ll+ FUN_001608-T2 433 AGEWRIVFWITAVVYVIGIVIFGLLVsG 460 456*****************76666541 PP >> Sugar_tr Sugar (and other) transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 12.3 8.2e-10 5.2e-06 33 188 .. 70 225 .. 34 234 .. 0.86 2 ! 23.5 0.0 4.9e-09 3.1e-05 74 237 .. 344 506 .. 309 516 .. 0.78 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 8.2e-10 Sugar_tr 33 glsksksskae...stvltglivsiflvGaiiGslfagllgdrfGRkkslliaivlfvigavlqaaakgkksvellivgRvlvGigvGlasvlvPl 125 g++ +k++ e s++l+g i+++f+ G ++ ++ g+lg+rfG ++ i++ ++++ ++l+ +a ++sv +li Rv+ G+++G+ + FUN_001608-T2 70 GFTIHKKA--EfdwSSKLQGTILGAFYYGYTAMQIPGGWLGQRFGGTRVFGICLGIASVLTMLTPLAA-RTSVAALITLRVIEGLALGALFPCNHA 162 33333322..1345999************************************************999.56************************* PP Sugar_tr 126 yisEiApkklRgalvslyqlaitfGillaaiiglglkktsnsdgWrillglqlvpallllill 188 s Ap++ R +l +++ ++ +G++l+ + ++k++ + gW ++ +++ll ++++ FUN_001608-T2 163 IWSKWAPPTERTRLFTITVAGCPVGTILSMPLSGVMSKYGFDGGWASVFYCFGAIGLLWFFVW 225 ******************************999999888888******999999998887776 PP == domain 2 score: 23.5 bits; conditional E-value: 4.9e-09 Sugar_tr 74 GRkkslliaivlfvigavlqaaakgkksvellivgRvlvGigv.GlasvlvPlyisEiApkklRgalvslyqlaitfGillaaiiglgl.kktsns 167 R+ ++ +++ ++i++++++ a + +++v+ + +G+g+ Gl + i iAp+ ++++ + ++ + G++ +i+g + +kt + FUN_001608-T2 344 TRRCVFTVGCTTASIFILITGYAS----TPAMAVAFLTIGVGItGLNASGYAVNILDIAPQYAGVIMGVTNVFGSAPGFISPQIVGILTpNKTAG- 434 578888888889999999998888....5555665556666642566677788899*********************************988888. PP Sugar_tr 168 dgWrillglqlvpall..llilllflPESPrwlvekgkee.eAkevlaklrgeedvdeelkeikdsleaeqee 237 Wri +++++v ++ ++++ll+ E w ++++++ +ke + +ee++ e l+e+k+ e+ +e FUN_001608-T2 435 -EWRIVFWITAVVYVIgiVIFGLLVSGELQPWAESNKDDDkGDKEDKNDGGDEEKAAETLDEEKKDKEKPEEG 506 .9********999876215667788889999997777777356666666777788889999998888776554 PP >> DUF4179 Domain of unknown function (DUF4179) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 1.4 8.8e+03 10 19 .. 34 43 .. 25 73 .. 0.61 2 ? 1.1 0.9 0.11 7.3e+02 22 34 .. 363 375 .. 344 411 .. 0.58 3 ? 6.5 0.0 0.0023 15 7 71 .. 439 500 .. 436 502 .. 0.80 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 1.4 DUF4179 10 aaaaaalial 19 ++a+ +++++ FUN_001608-T2 34 IVAIMIFLGI 43 4444444444 PP == domain 2 score: 1.1 bits; conditional E-value: 0.11 DUF4179 22 gsvlvspafaeyv 34 ++ +pa+a + FUN_001608-T2 363 TGYASTPAMAVAF 375 5555555555222 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0023 DUF4179 7 kkiaaaaaalialllgsvlvspafaeyvkeipiigsifellsddkglkaa...eeeysqeinksvtdn 71 + +++a++ +i++++++ lvs + p+ +s + ++dk++k++ ee+ ++++++ ++d+ FUN_001608-T2 439 VFWITAVVYVIGIVIFGLLVSGELQ------PWAESNKDDDKGDKEDKNDggdEEKAAETLDEEKKDK 500 457888888899989**********......7777776666666666666777**********99998 PP >> Anthrone_oxy Anthrone oxygenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 3 1.9e+04 39 58 .. 33 52 .. 25 61 .. 0.53 2 ? -0.0 0.5 0.22 1.4e+03 12 67 .. 112 165 .. 105 190 .. 0.61 3 ? -4.1 0.3 4 2.6e+04 1 26 [. 207 227 .. 207 235 .. 0.56 4 ? -2.2 0.1 1.1 6.8e+03 55 55 .. 364 364 .. 327 386 .. 0.54 5 ? 9.7 0.0 0.00021 1.3 29 72 .. 429 479 .. 402 511 .. 0.64 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 3 Anthrone_oxy 39 llaaAallllg.ivpfTllvm 58 +++ A+++ lg +v + l v+ FUN_001608-T2 33 YIV-AIMIFLGiCVQYALRVN 52 433.55533331333555544 PP == domain 2 score: -0.0 bits; conditional E-value: 0.22 Anthrone_oxy 12 fpalalaaalaylylarrarrsaaarlllaaAallllgivpfTllvmvplNnaLaa 67 ++ +++++l+++ + + ++ aar +a A++ l +i + l ++ p N a+ + FUN_001608-T2 112 GGTRVFGICLGIA-SVLTMLTPLAARTSVA-ALITLRVIEGLALGALFPCNHAIWS 165 4554555555555.3333444555555545.6777777777777777777766544 PP == domain 3 score: -4.1 bits; conditional E-value: 4 Anthrone_oxy 1 wallfkrgkavfpalalaaalaylyl 26 wa +f + f+a+ l+ +++++ l FUN_001608-T2 207 WASVF----YCFGAIGLLWFFVWQ-L 227 55566....566666666666655.3 PP == domain 4 score: -2.2 bits; conditional E-value: 1.1 Anthrone_oxy 55 l 55 FUN_001608-T2 364 G 364 1 PP == domain 5 score: 9.7 bits; conditional E-value: 0.00021 Anthrone_oxy 29 rarrsaaarlllaaAal.lllgivpfTllvmvplN.....naLaal.keaa 72 ++++ +r+++ ++a+ +++giv+f llv l n+ + + ++++ FUN_001608-T2 429 PNKTAGEWRIVFWITAVvYVIGIVIFGLLVSGELQpwaesNKDDDKgDKED 479 455566666655555555*************99884433322222231222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (522 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1701 (0.0665884); expected 510.9 (0.02) Passed bias filter: 897 (0.0351145); expected 510.9 (0.02) Passed Vit filter: 110 (0.00430613); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 4955.80 // Query: FUN_001609-T1 [L=505] Description: FUN_001609 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-41 142.3 35.9 3.2e-40 138.6 28.5 2.1 2 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.17 12.0 0.3 0.29 11.2 0.3 1.3 1 RTX N-terminal domain in RTX protein Domain annotation for each model (and alignments): >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.6 28.5 2.5e-44 3.2e-40 3 347 .] 58 440 .. 56 440 .. 0.83 2 ! 14.3 2.6 1.5e-06 0.02 123 172 .. 425 477 .. 425 500 .. 0.78 Alignments for each domain: == domain 1 score: 138.6 bits; conditional E-value: 2.5e-44 MFS_1 3 laaflaalgrsl....lgpalplll...............aedlgispseigllltlfslgyalaqllaGrlsdrfGrrrvlllglllfalgllll 79 +++fl ++++++ l++a+ ++ ++++++ + g++l+ f+ gya++ql+ G l+ r+G r++ +++l++ +ll FUN_001609-T1 58 IMTFLGFMNMYAlrvnLNVAIG-AMvnnhtiqakgytitrEAEFHWDSKLQGIVLGSFYYGYAFLQLPSGCLALRLGGTRIFGYAIFLASML-TLL 151 6666666666663333555555.334555555555555555569************************************999999999999.666 PP MFS_1 80 l.fa..sslwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfg....wravFlilailallaavla 168 + +a s++ ++++r+ Gl+ ga+fp+ +a+ ++w+p+ er+ + l +g +G+++ ++l+gll+ +g w +vF+ +++ ++l++ ++ FUN_001609-T1 152 TpVAtrYSVYGMIAVRAGEGLMLGAVFPCNHAIWSKWAPPLERTTLVTLAISGCHVGTIITMPLSGLLT-KYGfdggWASVFYCFGAAGILWFAAW 246 65555788888**********************************************************.5555899******************* PP MFS_1 169 alllprpppeskrkkpaee..........apapllpawkallrdpvlw.lllalllfglaffalltllply.qevlgls....glllaglllglaa 248 l++ ++p+ +++ +++e+ ++ +p wk++l++ ++w ++++ l++ ++++++l+ lp++ ++l+++ g +l + + FUN_001609-T1 247 QLVVHESPTVHPTISDEEKhyieksfdqgNEDVPIP-WKSILTSVPVWgIMFGNLASDWGLYTILICLPMFlLDILHFDiqtmG-----FLAATPF 336 ****************99999777777655555555.******************************************55555.....4444444 PP MFS_1 249 llgaigrlllgrlsdr.....lgrrrrlllallllllaalgllllsltesslwlllallllGf.gfglvfplllalvsdlapkeergtasglynta 338 l+ +++++++g +d l+ r+ +l +++++++a ++l+++ s+ +++ ++++G+ ++gl+ + +++ + d ap +++ ++g+ nt+ FUN_001609-T1 337 LVKSLSGPFGGITADLlrrkgLSTRSVRRLYFAVGAMGAGTFILAAGYAKSATIAVTCMCIGVaSSGLMHSGYNVNMLDIAP-RYACVIMGITNTV 431 44444455555555552226755677777777777888888888888888999999*************************9.9************ PP MFS_1 339 gslggalgp 347 g++ g+l+p FUN_001609-T1 432 GTITGFLSP 440 ******998 PP == domain 2 score: 14.3 bits; conditional E-value: 1.5e-06 MFS_1 123 lgllsagfglGaalGpllggllaslfg...wravFlilailallaavlaalll 172 +g+ ++ ++ ++l p+ g+++ + wr+vF+++ ++++++++l+ l+ FUN_001609-T1 425 MGITNTVGTITGFLSPMMVGFITVNKKveeWRTVFWVTFVIYFVGMLLFCTLM 477 78888999999999999999999555599****************99866665 PP >> RTX N-terminal domain in RTX protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.3 2.3e-05 0.29 64 139 .. 350 425 .. 346 440 .. 0.88 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 2.3e-05 RTX 64 aellrdaktaEaaltgistalgvvgavvsaaaaasvVGaPvalvvagitgalsgilealkqvalesvAnrlaekid 139 a+llr ++ ++ a+g++ga++ + aa+ + a +a+ i+ a sg++++ v + ++A r+a i FUN_001609-T1 350 ADLLRRKGLSTRSVRRLYFAVGAMGAGTFILAAGYAKSATIAVTCMCIGVASSGLMHSGYNVNMLDIAPRYACVIM 425 7888888888889999999**************************************999999999*****99884 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (505 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1044 (0.0408691); expected 510.9 (0.02) Passed bias filter: 561 (0.0219612); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.43s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4904.53 // Query: FUN_001610-T1 [L=327] Description: FUN_001610 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-05 23.8 1.6 9.2e-05 22.7 0.0 2.3 2 PAN_1 PAN domain 0.0002 22.0 6.0 0.00055 20.6 6.0 1.8 1 TSP_1 Thrombospondin type 1 domain 0.00072 20.3 4.4 0.0021 18.7 4.4 1.9 1 TSP1_spondin Spondin-like TSP1 domain 0.0037 17.8 2.9 0.005 17.3 0.2 2.4 2 PAN_4 PAN domain ------ inclusion threshold ------ 0.098 13.4 2.9 0.41 11.4 2.9 2.1 1 TSP1_CCN CCN3 Nov like TSP1 domain 2.1 9.2 9.7 0.58 10.9 5.7 2.1 2 TSP1_ADAMTS Thrombospondin type 1 domain Domain annotation for each model (and alignments): >> PAN_1 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.3 1.1 4.5e+03 27 49 .. 54 80 .. 43 91 .. 0.69 2 ! 22.7 0.0 2.2e-08 9.2e-05 13 58 .. 236 296 .. 225 310 .. 0.80 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 1.1 PAN_1 27 CaqrCaeekr....CrsftYnekskkC 49 C C r C+ f+ +++kC FUN_001610-T1 54 CTGSCGLGHRsrtgCHKFNKQGAQGKC 80 555555433345668888766666666 PP == domain 2 score: 22.7 bits; conditional E-value: 2.2e-08 PAN_1 13 gedkktvtvssaeeCaqrCaeekrCrsftYnek...............skkCllksessgs 58 ++++ + +s++ +Ca +C+ +++C+sf++ ++ k+Cll+s + + FUN_001610-T1 236 SHTIDGMWASNEVKCAMLCLRNPHCQSFNFKSTmgdtrqendsilgqdPKNCLLNSAMRLT 296 5455555567999********************9999999999999999999999887766 PP >> TSP_1 Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 6.0 1.3e-07 0.00055 2 45 .. 47 92 .. 46 97 .. 0.79 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 1.3e-07 TSP_1 2 pwseWspCsvTCgkGirvRqRtcksp..qkggepCtgeaqeteaCk 45 +w++W +C+ +Cg G+r R+ +k + +g+ ++ ++et aC+ FUN_001610-T1 47 DWGQWGACTGSCGLGHRSRTGCHKFNkqGAQGKCLPPSTEETGACS 92 6*******************99998873445555566667799996 PP >> TSP1_spondin Spondin-like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 4.4 5e-07 0.0021 5 49 .. 47 93 .. 44 97 .. 0.85 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 5e-07 TSP1_spondin 5 eWseWseCsktCgkGvqtRtRevivepqnggkpC..pellerrkCne 49 +W++W+ C +Cg G ++Rt + ++q + +C p+++e+ +C+ FUN_001610-T1 47 DWGQWGACTGSCGLGHRSRTGCHKFNKQGAQGKClpPSTEETGACSL 93 8*******************999999999999997555559999986 PP >> PAN_4 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.2 0.44 1.9e+03 16 25 .. 49 58 .. 42 81 .. 0.79 2 ! 17.3 0.2 1.2e-06 0.005 15 39 .. 244 268 .. 236 289 .. 0.80 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.44 PAN_4 16 dspeaCcaaC 25 +++ aC+ +C FUN_001610-T1 49 GQWGACTGSC 58 5789999999 PP == domain 2 score: 17.3 bits; conditional E-value: 1.2e-06 PAN_4 15 vdspeaCcaaCdedprCnawvfvkp 39 ++++ C+ +C ++p C+++ f FUN_001610-T1 244 ASNEVKCAMLCLRNPHCQSFNFKST 268 577789****************875 PP >> TSP1_CCN CCN3 Nov like TSP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 2.9 9.6e-05 0.41 6 24 .. 49 67 .. 46 77 .. 0.86 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 9.6e-05 TSP1_CCN 6 teWsaCSktCGlGvstRvs 24 +W aC+ +CGlG +R+ FUN_001610-T1 49 GQWGACTGSCGLGHRSRTG 67 58************99985 PP >> TSP1_ADAMTS Thrombospondin type 1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 5.7 0.00014 0.58 3 51 .. 48 92 .. 47 95 .. 0.76 2 ? -2.2 0.1 1.8 7.6e+03 29 44 .. 203 219 .. 199 224 .. 0.60 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00014 TSP1_ADAMTS 3 agkWseCsktCGgGvqtRkvqCvqkkgkelesdseCsaqkkPsetqsCn 51 g+W+ C+ +CG G ++R+ C + +++ ++ +C + +et +C+ FUN_001610-T1 48 WGQWGACTGSCGLGHRSRT-GCHKFNKQG--AQGKCL-PPSTEETGACS 92 589***************7.787776554..477888.66666677776 PP == domain 2 score: -2.2 bits; conditional E-value: 1.8 TSP1_ADAMTS 29 gkelesdseCsa.qkkP 44 ke+++ seC q P FUN_001610-T1 203 HKETQNVSECVDkQGVP 219 55666778887644445 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (327 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1096 (0.0429047); expected 510.9 (0.02) Passed bias filter: 636 (0.0248972); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3263.28 // Query: FUN_001611-T1 [L=2788] Description: FUN_001611 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0052 17.8 21.5 0.0052 17.8 21.5 20.6 23 Fez1 Fez1 ------ inclusion threshold ------ 1.9 9.0 5.1 5.3 7.5 0.1 4.1 4 Acetyltransf_9 Acetyltransferase (GNAT) domain 5.1 5.3 539.6 0.0095 14.3 34.9 14.2 13 CCDC39 Coiled-coil domain-containing protein 39 Domain annotation for each model (and alignments): >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 18.4 0.094 8e+02 45 179 .. 18 159 .. 9 175 .. 0.64 2 ? -3.6 18.7 2.2 1.8e+04 36 144 .. 65 180 .. 57 245 .. 0.57 3 ? -6.6 19.7 3 2.6e+04 46 152 .. 166 302 .. 147 307 .. 0.53 4 ? 1.6 28.2 0.056 4.8e+02 15 154 .. 295 431 .. 288 438 .. 0.56 5 ? -1.9 26.2 0.65 5.5e+03 10 160 .. 406 557 .. 397 568 .. 0.70 6 ? 1.7 24.7 0.051 4.4e+02 16 155 .. 564 707 .. 557 723 .. 0.66 7 ? -4.5 15.8 3 2.6e+04 37 154 .. 659 776 .. 658 783 .. 0.77 8 ? -1.9 22.8 0.63 5.4e+03 19 156 .. 732 866 .. 707 868 .. 0.66 9 ? -3.6 28.8 2.1 1.8e+04 8 154 .. 784 941 .. 780 965 .. 0.63 10 ? 3.0 28.5 0.02 1.7e+02 11 152 .. 924 1072 .. 916 1084 .. 0.72 11 ? -2.0 15.5 0.69 5.9e+03 38 155 .. 1081 1198 .. 1067 1225 .. 0.72 12 ? 3.0 23.3 0.021 1.8e+02 28 153 .. 1194 1337 .. 1190 1343 .. 0.72 13 ? 3.4 6.3 0.016 1.3e+02 35 94 .. 1345 1404 .. 1338 1415 .. 0.52 14 ? 0.4 18.3 0.13 1.1e+03 49 153 .. 1423 1538 .. 1406 1549 .. 0.65 15 ? -2.2 28.5 0.79 6.7e+03 17 167 .. 1447 1601 .. 1437 1606 .. 0.61 16 ? 2.2 16.1 0.035 3e+02 39 143 .. 1550 1654 .. 1538 1659 .. 0.70 17 ? -0.8 23.1 0.3 2.6e+03 23 137 .. 1608 1732 .. 1605 1759 .. 0.44 18 ! 17.8 21.5 6.1e-07 0.0052 49 174 .. 1757 1878 .. 1745 1880 .. 0.87 19 ? 0.2 7.4 0.15 1.2e+03 22 79 .. 1885 1942 .. 1880 1946 .. 0.84 20 ! 5.1 34.3 0.0048 41 15 164 .. 1899 2055 .. 1895 2070 .. 0.82 21 ? -6.5 22.8 3 2.6e+04 51 160 .. 2080 2187 .. 2060 2204 .. 0.36 22 ? -2.3 26.4 0.89 7.6e+03 18 173 .. 2182 2341 .. 2177 2350 .. 0.70 23 ? -4.1 27.6 3 2.5e+04 28 179 .. 2343 2511 .. 2338 2534 .. 0.49 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.094 Fez1 45 akleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekela.........lesdeakaqrqeaeeal 131 +k+ + e+++++l++ +++k+ +l+ ++ L+++k+ +e + ++ l+++ ++l e++++l+++++++ +++ + k +r+ +++l FUN_001611-T1 18 NKVYDLEQRCETLHKDVRQKQFQLDSSQAALAKQKKVTEEEKANAALLKKDNHSLSESIQDLERNREKILhdfhakegqIRCLDGKLNRT--QQQL 111 6788899*************************9976666666666666666666666666655544433322222223233333333333..3556 PP Fez1 132 eslkreverlkaeLkeerqrkeeqaksFeeERrtWqeeKekVirYqkQ 179 + + ++ +lk+eL + + +++++++ e+ + Ke +q+Q FUN_001611-T1 112 DGEVAKAAQLKNELDHLQFDHNQNVAKLERQSADLIKAKEANGLFQRQ 159 666666666777777766666666666555555555555555555555 PP == domain 2 score: -3.6 bits; conditional E-value: 2.2 Fez1 36 LraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqea.... 127 L+ + + l++++++ e++ +++ + +++k+ ++ ++++L+r++++ + k+ +l++e+ +l+ + +++ a+ ++++++ +ak+ + FUN_001611-T1 65 LKKDNHSLSESIQDLERNREKILHDFHAKEGQIRCLDGKLNRTQQQLDGEVAKAAQLKNELDHLQFDHNQNVAKLERQSADLIKAKEANGLFqrql 160 667777777777778888888888888888888888888888877777777777777777777766555544443333322222222211111112 PP Fez1 128 ...eealeslkreverlkae 144 +e++++l+++v+ l +e FUN_001611-T1 161 aghKERIRALENQVKSLGEE 180 22233333333333333322 PP == domain 3 score: -6.6 bits; conditional E-value: 3 Fez1 46 kleekeeqikeleeslesktle...........levceneLqrkkneaellrekvgkleeevselreelaelsaeekela................ 114 ++++ e+q+k+l e+ ++++++ ++ ++++++++ l re+ +k+e+e+++l+ +a++ ++e++++ FUN_001611-T1 166 RIRALENQVKSLGEEPDARAKKsssgsdsdvdwPSGVDSKVREAEASLILEREQREKIEKELHDLKAVAAQVYKNEDSQStssavkeiaidkeknv 261 445555555555444444433333444444444333444555555555566777777777777777766665444443334455555555555554 PP Fez1 115 ...lesdeakaqrqeaeealeslkreverlkaeLkeerqrk 152 ++++ak+++ ++e + ++l++ ++ ++++Lke+++++ FUN_001611-T1 262 tssDAEKKAKQRELDMECQRHNLEAVIKGMQEKLKEKEKEH 302 33344444555555556666667777777777776655544 PP == domain 4 score: 1.6 bits; conditional E-value: 0.056 Fez1 15 LKqQLkdsQaevaqklneivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaee 110 LK+ k+ +e+ ++ + + aL q+ e+++k ++ ++++++ ++ +e+k++++ +++ ++++ ++++ +++s++ FUN_001611-T1 295 LKEKEKEHRQEMYSQSQALSALEKQCTEFEKKSTALQNKVENSQKLIETKEQDIARLKANIKE---------------------VEDSRKQHSSHL 369 555555666666666666666666666666666666666666666666666666666655554.....................444444433333 PP Fez1 111 kelalesdeakaqrqea..................eealeslkreverlkaeLkeerqrkee 154 ++ ++e +++ +q++e+ e++++ l+r++erl+ ++e++++ + FUN_001611-T1 370 DNKVCELEQTVKQEEEKcvlvkreldatkaivferESKISDLNRQLERLRFDIQEKEKEMSL 431 33333333333333333344444444444444444999*************99998877654 PP == domain 5 score: -1.9 bits; conditional E-value: 0.65 Fez1 10 GEislLKqQLkdsQaevaqklneivaLraqlrelrakleekeeqikeleesl.esktlelevceneLqrkkneaellrekvgkleeevselreela 104 is L QL + ++++k +e+ +++e + +ek +++ + + l ++++ e+++ L++ ++ea + ++++ + +ev +l+++++ FUN_001611-T1 406 SKISDLNRQLERLRFDIQEKEKEMSLKEHKIQESVGEENEKLATAMNSIAVLeRQRSEVEEESRRALAKLSEEAAVAAKELQAARQEVIKLKDHVV 501 567777788888888888887776544455555554444433333333333303333334566777888888888888889999999999999888 PP Fez1 105 elsaeekelalesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqaksFe 160 +l++ + ++ e+++a + r++ +++l+ l+ ++ + + e ++e+++ ee++k + FUN_001611-T1 502 HLESLVSDQKREQQTADESRNSLSQKLQILEMDLANKNMEWTTEKAAMEEREKGYR 557 88777777778888888888888999999999999999999999999998888775 PP == domain 6 score: 1.7 bits; conditional E-value: 0.051 Fez1 16 KqQLkdsQaevaqklneivaLr.aqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaee 110 K+ k +Q + +k+ ++ ++ a+ r++ kle+++++++el+++l+ ++ l++ ++ kn++e l ++ + +eee ++ r+el++l+ e+ FUN_001611-T1 564 KNDSKALQHDY-KKACDLADMKsAEARDVIDKLESSQKHVQELQQRLSRTEATLKEKGSCIDALKNDNERLANEQQAMEEESQRSRNELNKLRGER 658 66667777776.57778888883579********************99999998888888888888888888888888888888888888876665 PP Fez1 111 kela.................lesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeq 155 k+ a + + ++ ++e+e l +++ ++e FUN_001611-T1 659 KTDAeelrkavdsvnvkleasM-------------LECSAKEKEIETLVMKVQSAASKCECL 707 5555344433333333333321.............344444455555554444444444333 PP == domain 7 score: -4.5 bits; conditional E-value: 3 Fez1 37 raqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeeale 132 +++ elr+++++ + +++ + ++k++e+e++ ++q + ++ e l+ + ee++ + +e l++++a+ ke++l+ ++ ++ e++ +l+ FUN_001611-T1 659 KTDAEELRKAVDSVNVKLEASMLECSAKEKEIETLVMKVQSAASKCECLETSLRIKEEKLVDSKELLQQKEANLKEASLALETKETLLIEMQCNLD 754 567788999999999999999999999999999999999999999999999999999999999998888777666666555555555566677888 PP Fez1 133 slkreverlkaeLkeerqrkee 154 + +++v l++ ++ + ++ee FUN_001611-T1 755 KTSKTVHDLEQTMARCEMQREE 776 8888888888887655544444 PP == domain 8 score: -1.9 bits; conditional E-value: 0.63 Fez1 19 LkdsQaevaqklneivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekela 114 Lk++ + +k +++++ +l +++++++ e+++ ++e +++ +l+v++n+ ++ ++ +++l++ +++e+++++ee ++ ++e l+ FUN_001611-T1 732 LKEASLALETKETLLIEMQCNLDKTSKTVHDLEQTMARCEM---QREEDLKVLKNKDSEICSLEKQLNDVRAVTDKELAKMKEECNARQNEFVFLQ 824 44444455555555555555555555555555555554443...3445566666666666777777777777778888888888887666666666 PP Fez1 115 lesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqa 156 + d+ ++ r ++e +l+++++e+ + ++ L rqr +q+ FUN_001611-T1 825 ERLDNVETLRGNKEGELTAVNQELSKANKDLDDLRQRLASQE 866 777778888888899999999999999999999999877765 PP == domain 9 score: -3.6 bits; conditional E-value: 2.1 Fez1 8 ksGEislLKqQLkdsQaevaqklneivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreel 103 k Ei L +QL d+ a v+ +e+ +++ ++ +++ +e+++++e+ +k+ el +++eL++++++ + lr+++ + ee v + + e FUN_001611-T1 784 KDSEICSLEKQLNDVRA-VTD--KELAKMKEECNARQNEFVFLQERLDNVETLRGNKEGELTAVNQELSKANKDLDDLRQRLASQEELVCNHELEK 876 77899999999999987.444..4899999999999999999999999999999999999999999999999999999998888777665554333 PP Fez1 104 aelsaeekela...........lesdeakaqrqea..............eealeslkreverlkaeLkeerqrkee 154 a+l+++ ++++ + + l++ + e e+lk++L++ + +e+ FUN_001611-T1 877 ARLASDLEQTScalearkreleE-----------TqeklkaenlllvekISGLTQSQDEEEELKQRLEQATALTES 941 33333322222122222222210...........122334445555554333444444445555555544444443 PP == domain 10 score: 3.0 bits; conditional E-value: 0.02 Fez1 11 EislLKqQLkdsQaevaqklneivaLraqlr.......elrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevs 97 E LKq L ++ a +k++e+ a+ a+l +l+a l+e +++ +le++l++k ++le+ +qrk++ +++++ kv +l evs FUN_001611-T1 924 EEEELKQRLEQATALTESKTEEVKAIMAKLEasegersQLSAMLDELCNTNFKLEDQLKEKIAQLEETTAAVQRKEEMSSTTEAKVRELADEVS 1017 556799999999999999999998887776522111114556677777888899**************************************** PP Fez1 98 elreelaelsaeekelalesdeakaqrqeaeealeslkreverlkaeLkeerqrk 152 l+e+l++ s ++k+ + ++d+ ++ +ea++ l+s + e+ k+++++e ++ FUN_001611-T1 1018 TLQEQLVTISDAAKHEKEQNDSLSMKLEEATKVLQSKEMELRLTKESFEAETSNH 1072 ********88877777666666666666555555555555544444444444332 PP == domain 11 score: -2.0 bits; conditional E-value: 0.69 Fez1 38 aqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeeal 131 q+ l++++++ e+++ ++ l+ +++e+ + ++L+ + +++ l+ kv +l+++ + l+e+ +el ++ ++++ + ++ +++ + + + l FUN_001611-T1 1081 LQTESLKEQISSLMEKLDGISGVLDVRDQEIASLIKQLKSEAEDKAGLEVKVDELSSKSTILQEKNVELVNNLEQASSALRTKQDEFNLKCSVL 1174 4555677788888888888888888888888888888888888888888888888888888888777766665555544444444444457788 PP Fez1 132 eslkreverlkaeLkeerqrkeeq 155 ++l+ + er +eLke+ +ke+ FUN_001611-T1 1175 DELQSQSEREISELKEQGTSKENF 1198 888888888888888877776654 PP == domain 12 score: 3.0 bits; conditional E-value: 0.021 Fez1 28 qklneivaLraqlrelrakleekeeqikeleeslesktle...........levceneLqrkkneaellrekvgkleeevselreelaelsaee 110 +k n +++L+ ++ +l+ +e+k+ ++k+l+++++s + le e eL+rk + l k++ e+ vsel+++l+ +++e FUN_001611-T1 1194 SKENFVLQLQDKCNQLEGCIERKDLELKDLRSKAKSCESTagseisqlreeLENKETELSRKVLVLQELTVKLEGKESLVSELKQKLEIKEEEM 1287 6777788888888888888888888888888888887776777777777778888888888876677777777777777777777666644433 PP Fez1 111 kela........lesdeakaqrqeaeealeslkreverlkaeLkeerqrke 153 + l+ s++a++q++e ++++++lk++++ l+++L +e +++ FUN_001611-T1 1288 SLLKrdldnlagELSKNAQNQEEE-SNNVQELKHNIQTLETRLLKETAKSG 1337 333366666654455666666664.7799*************999988765 PP == domain 13 score: 3.4 bits; conditional E-value: 0.016 Fez1 35 aLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgklee 94 +++ ++ ++a+le ke++i el+e+ + + ++ ++en+++ ++++++ l+++ +le+ FUN_001611-T1 1345 KIQEKMDSTTASLEGKESEIAELKENKFASEDKVSKLENQVDNATKNVSALQNEKANLEK 1404 334444445555555555555555555555555555555555555555555555555544 PP == domain 14 score: 0.4 bits; conditional E-value: 0.13 Fez1 49 ekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekela...........lesdeakaqrqea.... 127 e+e+ + e ++ l++k+ e ++Lq++k+e +l++ + +le++v + +e +l++++++ a + FUN_001611-T1 1423 EREAGLLERSQLLKAKSEECASALDQLQKSKEEITMLKDTILQLENDVCSKNQEKINLEESHEKFAekaqnresellE-----------Tckvl 1505 567777888888999999999999999999999999999999999999888777666555555444233333333332...........23333 PP Fez1 128 .......eealeslkreverlkaeLkeerqrke 153 e++++ + ++e lk+e + rq+ + FUN_001611-T1 1506 eeeklqlVEKTQAFEGTLEALKQECSVHRQSYK 1538 222222255555555555555555555555443 PP == domain 15 score: -2.2 bits; conditional E-value: 0.79 Fez1 17 qQLkdsQaevaqklneivaLraqlrelrakleekeeqikeleeslesktlel....evceneLqrkkneaellrekvgkleeevselreelael 106 QL+ s +e++ + i++L ++ +++ + ee ++ e++++++ el +v+e+e + ++++ + ++ l++e+s r++ +++ FUN_001611-T1 1447 DQLQKSKEEITMLKDTILQLENDVCSKNQEKINLEESHEKFAEKAQNRESELletcKVLEEEKLQLVEKTQAFEGTLEALKQECSVHRQSYKKA 1540 6777777777777777777777776666666666666666666666666664111133333333334555555556666666666666666666 PP Fez1 107 saeekelalesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqaksFeeERrtWq 167 ++ ++e ++e+++ ++ +++++l++ ++++ r + eLke r++ ++ + +e ++W+ FUN_001611-T1 1541 CELADEKSVECRDLVDKLDDSQKHLQETRNHLTRAEIELKEAREEAKQAFFEKNELAEKWS 1601 6666666677777777777778899999999999999999888876655333333345565 PP == domain 16 score: 2.2 bits; conditional E-value: 0.035 Fez1 39 qlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeeale 132 ++r+l kl++++++++e++++l+ ++el++ ++e +++ e++ l ek ++ ee++ e+l+ +e k+ + e +++ + + +ale FUN_001611-T1 1550 ECRDLVDKLDDSQKHLQETRNHLTRAEIELKEAREEAKQAFFEKNELAEKWSNKTEELQTALEALQGEICEYKARISELSSQLESSMVSVKALE 1643 78999999**********************9999999999888888888888877777777777776555444444444433333333455555 PP Fez1 133 slkreverlka 143 s+kr+ve++ + FUN_001611-T1 1644 SEKRRVEQILE 1654 55555555544 PP == domain 17 score: -0.8 bits; conditional E-value: 0.3 Fez1 23 QaevaqklneivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrk..........kneaellrekvgkleeevselreelael 106 Q+ + + +ei + +a++ el+++le++ +k le++ + ++ le ++eL+++ + e e++ + e+ ++el++e++ l FUN_001611-T1 1608 QTALEALQGEICEYKARISELSSQLESSMVSVKALESEKRRVEQILEHTKEELREAvqklkaieveNVEREVTIRSNQDSEKLIAELKDEMKLL 1701 5555555566666666666666666666666666666666666666666666666544444444332222222222333333333444444444 PP Fez1 107 saeekelalesdeakaqrqeaeealeslkre 137 + ++ el++e d+aka+ +e +++++s++++ FUN_001611-T1 1702 EVNKVELKTELDQAKAEIKEFKNTVHSMEEQ 1732 4444444444444444333333333333222 PP == domain 18 score: 17.8 bits; conditional E-value: 6.1e-07 Fez1 49 ekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeealeslkreverlk 142 e++++el ++ e+ +ele+++n L +++++e l+ ++g e+++ l+ ++++l+ e ++l++e+ + ++ + e + +l+++v +l+ FUN_001611-T1 1757 LAEKKMDELLKEKEQNVKELEKSQNLLTARCSQVEKLQRNLGDQTEQLEALKAKVSSLTDECDSLKIEHLNCQT--S--EAGALKLQEQVLELE 1846 4689999**************************************************88877777666666444..3..3467899******** PP Fez1 143 aeLkeerqrkeeqaksFeeERrtWqeeKekVi 174 + L+ e+ + e +++F+e + W++eK k + FUN_001611-T1 1847 HLLAREKSNAEALMQAFQEQEESWESEKAKMM 1878 ****************************9975 PP == domain 19 score: 0.2 bits; conditional E-value: 0.15 Fez1 22 sQaevaqklneivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkk 79 s a++ ++e +L+++l el++++++ke++ el ++++ k+ + ++ +Lq k FUN_001611-T1 1885 SDADQVLLVEENDKLKTKLEELEKEMNTKEREHLELLQQSKRKASSRANLNSDLQAKI 1942 556666667777899*********************9999999999999999998775 PP == domain 20 score: 5.1 bits; conditional E-value: 0.0048 Fez1 15 LKqQLkdsQaevaqklneivaLraqlr...........elrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevs 97 LK+ L ++ +e+++k e ++L q + +l+ak+++ e q++el+ sl++k+ e+ v e+ L+++k+e+++l+ k + + FUN_001611-T1 1899 LKTKLEELEKEMNTKEREHLELLQQSKrkassranlnsDLQAKITQLECQCEELRYSLKQKDEEIFVKEQSLKQSKQEVSNLESKYAAAADVER 1992 999***************99995444322322244444678999999****************************************9999999 PP Fez1 98 elreelaelsaeekelalesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqaksFeeERr 164 elr++l e+++ +l++++de ++r+ + ++e+l++ + ++eL+e r++k+++ k eeER FUN_001611-T1 1993 ELRHHLGEVTQ---QLECSKDEKSTERE-KIIEVEKLTEALTVAEKELAELRAEKQDKDKWLEEERV 2055 ****9999655...45566666555555.57789999999999999999999999999999999996 PP == domain 21 score: -6.5 bits; conditional E-value: 3 Fez1 51 eeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeealeslkreverlkae 144 + ++ + +e +++ + +++ ++ L+ +++e+ +l ++++ e+e++e ++ ++ + + ek ++++ d ++rq+ ++l++ +r++e+ +ae FUN_001611-T1 2080 KLKLASKNEDIQEMDSVVNQQRHALKTAQQEKTVLLAEAEEREREFEEEKKLMSGSFSYEKIQQYNADL-SEERQN-VSRLQEQSRDLEKKRAE 2171 222222222222222223333333333344444444444444444444444333322222222222222.222222.23344444444444444 PP Fez1 145 LkeerqrkeeqaksFe 160 L+ + +++ ++ + FUN_001611-T1 2172 LESANSCLQKKLAELQ 2187 4333333333322222 PP == domain 22 score: -2.3 bits; conditional E-value: 0.89 Fez1 18 QLkdsQaevaqklneivaLraqlrelrakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeek 111 L ++Q+ ++ ++e + + +l +kle +++++ l++sl s+++ + +++e + + l++k++ + v++l+++ + ++++ + FUN_001611-T1 2182 KLAELQNRHKNDGEER---KVTEDDLYSKLELFQSETEALKSSLGSRDATVSALSEEKTKLLGTIKSLEDKLSVSTQTVRDLQQKCEWMNEKLE 2272 5555555555555543...556667888899999999999999999999998888888888777777777777666666666666665555444 PP Fez1 112 ela.......lesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqaksFeeERrtWqeeKekV 173 +l e+d ++++++ +le+ +++++l+++L +e + ke+ +++ +e ++ ++eK V FUN_001611-T1 2273 TLRveksaleKEKDGFVLRKSQEKMNLEHFMKKMQELQHKLDKESKMKEKSMEAVNEMEKILEKEKKSV 2341 44422322224555555555566889999999999*********9999999999999889999999877 PP == domain 23 score: -4.1 bits; conditional E-value: 3 Fez1 28 qklneivaLraqlr...el.rakleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekela... 114 +k +ei ++ a + e+ + +++eke +i el ++e+ + +le+ ++ L+++++e ++++++++ee +e++e + + ++ + + FUN_001611-T1 2343 KKSKEIAEMEAMFKladEMhEGTIKEKEGKIVELTFAYEDLRNKLEKQKKALEKTCEEFGSVKKQLKQAEERAEEMKEMYEG-ELDRVKFElrd 2435 5555555555555522211133566666666666666666666666666666666666666666666666666666664333.22222222445 PP Fez1 115 ....................................lesdeakaqrqeaeealeslkreverlkaeLkeerqrkeeqaksFeeERrtWqeeKek 172 + +eak++ ++ + ++l++ev rl++eL++ r FUN_001611-T1 2436 snndcallrgenedlkrtadenlnhtswetekkkllHQLEEAKMKLNQ--PKGTHLEAEVRRLEEELEKTR----------------------- 2504 555555544333222222222222222222333332334444443332..344555555555555555555....................... PP Fez1 173 VirYqkQ 179 V+ kQ FUN_001611-T1 2505 VLAAEKQ 2511 4444444 PP >> Acetyltransf_9 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.1 0.84 7.2e+03 7 35 .. 224 252 .. 220 268 .. 0.72 2 ? -2.9 0.0 1.1 9.2e+03 36 71 .. 1503 1538 .. 1487 1540 .. 0.80 3 ? 0.1 0.1 0.12 1.1e+03 76 108 .. 1635 1667 .. 1632 1672 .. 0.90 4 ? 7.5 0.1 0.00062 5.3 9 67 .. 1858 1914 .. 1852 1921 .. 0.79 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 0.84 Acetyltransf_9 7 eseldevlellayaFqdedspaelkeafr 35 e+el++ ++ a+++++eds+++ + ++ FUN_001611-T1 224 EKELHDLKAVAAQVYKNEDSQSTSSAVKE 252 7899****************984333333 PP == domain 2 score: -2.9 bits; conditional E-value: 1.1 Acetyltransf_9 36 klleegrvlgafdngklvstlallpfelnvpGktlk 71 k+lee++ ++++ +tl +l++e++v+ +++k FUN_001611-T1 1503 KVLEEEKLQLVEKTQAFEGTLEALKQECSVHRQSYK 1538 678888889999999999************988776 PP == domain 3 score: 0.1 bits; conditional E-value: 0.12 Acetyltransf_9 76 tgVavapehrrrgvlskLlkrlleemkergqpl 108 ++V+v++ + +++ ++++l+++ ee++e q+l FUN_001611-T1 1635 SMVSVKALESEKRRVEQILEHTKEELREAVQKL 1667 69*************************998877 PP == domain 4 score: 7.5 bits; conditional E-value: 0.00062 Acetyltransf_9 9 eldevlellayaFqdedspaelkeafrklleegrvlgafdngklvstlallpfelnvpG 67 l ++++ ++++++ e+ + ++++++k + ++vl++++n+kl ++l l+ e+n+ + FUN_001611-T1 1858 ALMQAFQEQEESWESEKAK--MMASLNKSSDADQVLLVEENDKLKTKLEELEKEMNTKE 1914 4455555556666655555..899****************************9999977 PP >> CCDC39 Coiled-coil domain-containing protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 17.8 6.9e-06 0.058 221 341 .. 22 142 .. 11 152 .. 0.83 2 ? -1.3 11.4 0.058 4.9e+02 249 384 .. 134 272 .. 129 283 .. 0.88 3 ? 7.5 64.8 0.00013 1.1 274 541 .. 291 551 .. 267 585 .. 0.85 4 ? 12.5 38.7 4e-06 0.034 226 432 .. 595 798 .. 584 803 .. 0.97 5 ? 2.2 62.0 0.0052 44 230 538 .. 803 1117 .. 800 1136 .. 0.87 6 ? 1.9 17.9 0.0063 54 705 816 .. 1138 1250 .. 1125 1262 .. 0.81 7 ? 14.3 34.9 1.1e-06 0.0095 239 412 .. 1237 1410 .. 1232 1415 .. 0.57 8 ? 0.2 20.4 0.021 1.8e+02 239 364 .. 1420 1545 .. 1412 1553 .. 0.90 9 ? 2.5 83.8 0.0041 35 162 543 .. 1550 1921 .. 1543 1925 .. 0.87 10 ? -2.3 59.3 0.12 1e+03 237 496 .. 1925 2189 .. 1919 2205 .. 0.65 11 ? 7.0 35.0 0.00019 1.6 228 402 .. 2203 2369 .. 2182 2373 .. 0.65 12 ? 6.1 8.6 0.00035 2.9 313 374 .. 2369 2430 .. 2364 2439 .. 0.85 13 ? -1.4 15.8 0.062 5.3e+02 687 779 .. 2442 2539 .. 2437 2544 .. 0.82 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 6.9e-06 CCDC39 221 qrdedIqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqrae 316 +++ + l +++++ + ++++ +++l +qkk e++k+n + l+k+ ++l +++++l ++ +++ + + e ++ +l +l+r++++l + a+ FUN_001611-T1 22 DLEQRCETLHKDVRQKQFQLDSSQAALAKQKKVTEEEKANAALLKKDNHSLSESIQDLERNREKILHDFHAKEGQIRCLDGKLNRTQQQLDGEVAK 117 55667778888999999999999999999******************************************************************* PP CCDC39 317 ikelkkeieekekkleklekkleal 341 ++lk+e+++ + ++ +kle+ FUN_001611-T1 118 AAQLKNELDHLQFDHNQNVAKLERQ 142 ********98765555555554443 PP == domain 2 score: -1.3 bits; conditional E-value: 0.058 CCDC39 249 eqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetl.kkqlsrlatdl...enqraeikelkkeieekekkleklekklea 340 ++ + le+q+++ + ++ +r+l+ ++e+ + le+++++l +e ++ kk+ s +++d+ + ++++e ++++ ++++ ek+ek+l + FUN_001611-T1 134 QNVAKLERQSADLIKAKEANGLFQRQLAGHKERIRALENQVKSLGEEPDARaKKSSSGSDSDVdwpSGVDSKVREAEASLILEREQREKIEKELHD 229 566789999999999999******************************99648888999999955568999************************* PP CCDC39 341 lkekleevknktlsaeerakeleklleeeekrlkeldkeikklk 384 lk+ ++v++++ + ++ ++++ ++ek+ + d+e k + FUN_001611-T1 230 LKAVAAQVYKNE-DSQSTSSAVKEIAIDKEKNVTSSDAEKKAKQ 272 *********998.7788889999999999999988888877655 PP == domain 3 score: 7.5 bits; conditional E-value: 0.00013 CCDC39 274 klsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleee 369 kl+e+ ke+ +e+ + ++ + +l kq ++++++ ++ ++++++ +k ie+ke+ + +l++++++ ++ k+++ ++ +++ele+ +++e FUN_001611-T1 291 MQEKLKEKEKEHRQEMYSQSQALSALEKQCTEFEKKSTALQNKVENSQKLIETKEQDIARLKANIKEVEDS---RKQHSSHLDNKVCELEQTVKQE 383 34589999999999999999999999999999999999999999999999999999999999988877755...55667778************** PP CCDC39 370 ekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeel 465 e++ +++e++ k f+++ ++++l+ + + l+ +i+ e++++ ++ki ++ + + +e l +++ +i ler+ +++++e s +l FUN_001611-T1 384 EEKCVLVKRELDATKAIVFERESKISDLNRQLERLRFDIQEKEKEMSLKEHKI---QESVGEENEKLATAMNSIAVLERQRSEVEEE-SRRALAKL 475 ***************************************98887766655555...5677788899999999********9998877.44688999 PP CCDC39 466 ekkieeLeeeldekkktqnlLqsqikkleeelrklkkkleklkeeleklkeklqelelenesgekelkklkkekee 541 ++ + +el+ +++ L+ ++ +le+ + k++ + e+ ++l++klq le+ +++ e ++ k+ ee FUN_001611-T1 476 SEEAAVAAKELQAARQEVIKLKDHVVHLESLVSDQKREQQTADESRNSLSQKLQILEMDLANKNMEWTTEKAAMEE 551 9****************************************************98888887777777666666655 PP == domain 4 score: 12.5 bits; conditional E-value: 4e-06 CCDC39 226 Iqklaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelk 321 +++++ ++el++++++ +++l+e+ + + k++n+ l ++ + +e++ ++ r+el++l e ++ +e l+k ++ ++ +le+ + e + ++ FUN_001611-T1 595 LESSQKHVQELQQRLSRTEATLKEKGSCIDALKNDNERLANEQQAMEEESQRSRNELNKLRGERKTDAEE---LRKAVDSVNVKLEASMLECSAKE 687 5678999*********************************************************999999...*********************** PP CCDC39 322 keieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaikn 417 keie+ k++ + k e l++ l+ ++k ++ +e +++ e+ l+e+ +l++ ++ + +++ l k+s+ +++l++ + e++ + + +kn FUN_001611-T1 688 KEIETLVMKVQSAASKCECLETSLRIKEEKLVDSKELLQQKEANLKEASLALETKETLLIEMQCNLDKTSKTVHDLEQTMARCEMQREEDLKVLKN 783 ************************************************************************************************ PP CCDC39 418 lkkkiakleqellkq 432 +++i +le++l+ FUN_001611-T1 784 KDSEICSLEKQLNDV 798 ***********9865 PP == domain 5 score: 2.2 bits; conditional E-value: 0.0052 CCDC39 230 aeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkke 323 +e++++kee + +++e ++ l+n ++ + e +++ +++lsk ++l +l ++la+ e+ v + rla+dle++ ++ k+e FUN_001611-T1 803 DKELAKMKEECNARQNEFVFLQERLDNVETLRGNKEGELTAVNQELSKANKDLDDLRQRLASQEELVCNHELEKARLASDLEQTSCALEARKRE 896 68999*******************************************************99999988888888999***************** PP CCDC39 324 ieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaikn 417 +ee ++kl++ + l + l + ++++ ++++r++++ +l e + ++ k+++++++ + + s l el + + le +++ a++++ FUN_001611-T1 897 LEETQEKLKAENLLLVEKISGLTQSQDEEEELKQRLEQATALTESKTEEVKAIMAKLEASEGERSQLSAMLDELCNTNFKLEDQLKEKIAQLEE 990 **999999988888888888888888888888899999999999999999999999999999999999************************** PP CCDC39 418 lkkkiakleqellkqqellynqefqiqqlerkvarlkge..rseeekeelekkieeLeeeldekkktqnlLqsqik....kleeelrklkkkle 505 + ++++e+ + + + ++ ++ +l++++ +++ + +e+++ l k+ee ++ l+ k+ + +l +++ + + + e l ++e FUN_001611-T1 991 TTAAVQRKEEMSSTTEAKVRELADEVSTLQEQLVTISDAakHEKEQNDSLSMKLEEATKVLQSKEMELRLTKESFEaetsNHRCEKETLYLQTE 1084 ********************************9999998877777788899999999999999998888887655411115666777788999* PP CCDC39 506 klkeeleklkeklqelelenesgekelkklkke 538 +lke+ ++l ekl+ ++ ++ ++e+ +l+k+ FUN_001611-T1 1085 SLKEQISSLMEKLDGISGVLDVRDQEIASLIKQ 1117 ***************999999999998877776 PP == domain 6 score: 1.9 bits; conditional E-value: 0.0063 CCDC39 705 dseeleekka.LeeqlreaneklkekreeleeleeeleeleqeleeleekeeelketleekeqeleklekeieeqkeKikRadkqlkklvkeir 797 +s l+ek+ L ++l++a++ l++k++e++ + l+el+++ e++++elke+ ++ke+ + +l+ + ++++ i+R d +lk l+ + + FUN_001611-T1 1138 KSTILQEKNVeLVNNLEQASSALRTKQDEFNLKCSVLDELQSQ---SEREISELKEQGTSKENFVLQLQDKCNQLEGCIERKDLELKDLRSKAK 1228 44456666668*******************9999999999999...599********************************************* PP CCDC39 798 kkketkse........leekDielrel 816 ++++t+ l e +e+ FUN_001611-T1 1229 SCESTAGSeisqlreeL-----ENKET 1250 99988776666433333.....33333 PP == domain 7 score: 14.3 bits; conditional E-value: 1.1e-06 CCDC39 239 eirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkle 332 ei++ +eele +++ l++ +el k++ +e +s+l+++l+ eee++ l+ +++ l +ls+ a++ e++ ++++elk +i++ e++l FUN_001611-T1 1237 EISQLREELENKETELSRKVLVLQELTVKLEGKESLVSELKQKLEIKEEEMSLLKRDLDNLAGELSKNAQNQEEESNNVQELKHNIQTLETRLL 1330 4444445555555555555555555666666666666666666666666666666666666666666666666666666666666666666666 PP CCDC39 333 klekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgae 412 k ++k l e+l ++++k s+ + ++ e ++e ++++ + + +++kl ++ + +++++ l++++++le +++ae FUN_001611-T1 1331 KETAKSGSLAEELGKIQEKMDSTTASLEGKESEIAELKENKFASEDKVSKLENQVDNATKNVSALQNEKANLEKLLRNAE 1410 66666666666666666666666666666666666666666666666666666666666666666666666666555554 PP == domain 8 score: 0.2 bits; conditional E-value: 0.021 CCDC39 239 eirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkle 332 + +e+++ l e++++l+ +e+ + ++++ +++++ l+++ +le+++ + ++e l ++ +++a++ +n+++e+ e+ k +ee++ +l FUN_001611-T1 1420 IEKEREAGLLERSQLLKAKSEECASALDQLQKSKEEITMLKDTILQLENDVCSKNQEKINLEESHEKFAEKAQNRESELLETCKVLEEEKLQLV 1513 66899999********************************************************************************999999 PP CCDC39 333 klekklealkekleevknktlsaeerakelek 364 + ++ +e + e l+++ + + ++a+el++ FUN_001611-T1 1514 EKTQAFEGTLEALKQECSVHRQSYKKACELAD 1545 99999999999999887777777777777765 PP == domain 9 score: 2.5 bits; conditional E-value: 0.0041 CCDC39 162 ereklseelnekkkklekevtetqslqieLdrtaeefrqlhaeRqqLiqqWeetvkqlqqrdedIqklaeeieelkeeirekkeeleeqkkfle 255 e l ++l + +k l+++ + + ++ieL + ee +q+ e+++L ++W + ++l + +e+l+ ei e k++++e ++ le FUN_001611-T1 1550 ECRDLVDKLDDSQKHLQETRNHLTRAEIELKEAREEAKQAFFEKNELAEKWSNKTEEL----------QTALEALQGEICEYKARISELSSQLE 1633 566788999******************************************9876655..........55677777777777777777778888 PP CCDC39 256 nqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelkkeieekekkleklekklealkekleevk 349 + k le++ + e+ l ++eel+e++++l+ +e e ++ ++ r+++d e+ a elk+e++ e + +l+ +l+++k++++e+k FUN_001611-T1 1634 SSMVSVKALESEKRRVEQILEHTKEELREAVQKLKAIEVE-NVEREVTIRSNQDSEKLIA---ELKDEMKLLEVNKVELKTELDQAKAEIKEFK 1723 88899999999999999999*****************999.8888888888888888765...556899999999999999************* PP CCDC39 350 nktlsaeerakeleklleeeekrlkeldkeikklkea.....lfkksqelkelkskektleaeisgaeaaiknlkkkiakleqellkqqellyn 438 n+ s+ee+ + ++ + +r+++++ke++ l e+ l +k+q++kel++ + l+a+ s++e+ ++nl + ++le+ k +l + FUN_001611-T1 1724 NTVHSMEEQHSSALAMKDSDFERKTAAMKEQEVLAEKkmdelLKEKEQNVKELEKSQNLLTARCSQVEKLQRNLGDQTEQLEALKAKVSSLTDE 1817 ******************************9876554111115678999*******************************************97 PP CCDC39 439 qefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlL....qsqikkleeelrklkkkleklkeelek.lkeklqelelenes 527 + k+++l+ ++se +l++++ eLe l++ k++++ L q+q ++ e+e k+ +l+k+++ + l e+ ++l+ +e FUN_001611-T1 1818 CD------SLKIEHLNCQTSEAGALKLQEQVLELEHLLAREKSNAEALmqafQEQEESWESEKAKMMASLNKSSDADQVlLVEENDKLKTKLEE 1905 66......469******************************999987755558899999************99987776257899999999999 PP CCDC39 528 gekelkklkkekeell 543 eke++++++e+ ell FUN_001611-T1 1906 LEKEMNTKEREHLELL 1921 9999999999998876 PP == domain 10 score: -2.3 bits; conditional E-value: 0.12 CCDC39 237 keeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevet.......lkkqlsrlatdlenqraeikelkke 323 k +++++ + ++ ++ + +++ +el +++k++++++ + lk+ ++e+++le+++ + l+++l +++++le + e + +++ FUN_001611-T1 1925 KRKASSRANLNSDLQAKITQLECQCEELRYSLKQKDEEIFVKEQSLKQSKQEVSNLESKYAAaadvereLRHHLGEVTQQLECSKDEKSTEREK 2018 4455555555555555555555555555555555555555555555555555555555554411111115555555555555444444444444 PP CCDC39 324 ieekekkleklekklealke.kleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskektleaeisgaeaaik 416 i e ek e+l+ ++l e + e+ +++++ eer++ +e+ e + +++++ k+i+ lk +l k+++++e+ s ++++ +++a+++++ FUN_001611-T1 2019 IIEVEKLTEALTVAEKELAElRAEKQDKDKWLEEERVRIVEAAKEFAVQQEQTFVKKIDNLKLKLASKNEDIQEMDSVVNQQRHALKTAQQEKT 2112 433333333333333333222455667788889************************************************************* PP CCDC39 417 nlkkkiakleqellkqqellynqefqiqqlerkvarlkgerseeekeelekkieeLeeeldekkktqnlLqsqikkleee 496 l ++ ++ e+e+++ ++l+ f+ +++++ a l++er++ +l+++ + Le++ +e ++ ++ Lq+++ +l++ FUN_001611-T1 2113 VLLAEAEEREREFEEEKKLMS-GSFSYEKIQQYNADLSEERQN--VSRLQEQSRDLEKKRAELESANSCLQKKLAELQNR 2189 *************99999886.788888888888888887653..45566666666666666666666666666666664 PP == domain 11 score: 7.0 bits; conditional E-value: 0.00019 CCDC39 228 klaeeieelkeeirekkeeleeqkkflenqkennkelekkikelerklsklreelkeleeelaelenevetlkkqlsrlatdlenqraeikelk 321 +l ++e ++e + k++l + + + +e+ +l +ik+le kls ++ ++l+++++ +++++etl+ + s l+++ + FUN_001611-T1 2203 DLYSKLELFQSETEALKSSLGSRDATVSALSEEKTKLLGTIKSLEDKLSVSTQTVRDLQQKCEWMNEKLETLRVEKSALEKEKDGFVLRK---- 2292 333344444455555555555555555555555555555555555555555555555555555555555555544444443333333333.... PP CCDC39 322 keieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlkeldkeikklkealfkksqelkelkskek 402 +++ +le++ kk+++l+ kl+++++++ + e ++e+ek+le+e+k ++ kei+++ ea+fk e++e kek FUN_001611-T1 2293 ---SQEKMNLEHFMKKMQELQHKLDKESKMKEKSMEAVNEMEKILEKEKKSVEKKSKEIAEM-EAMFKLADEMHEGTIKEK 2369 ...3677899*************************************************996.789999999998776666 PP == domain 12 score: 6.1 bits; conditional E-value: 0.00035 CCDC39 313 qraeikelkkeieekekkleklekklealkekleevknktlsaeerakeleklleeeekrlk 374 ++++i el e+ ++klek +k le++ e+ +vk++ +aeera+e+++++e e +r k FUN_001611-T1 2369 KEGKIVELTFAYEDLRNKLEKQKKALEKTCEEFGSVKKQLKQAEERAEEMKEMYEGELDRVK 2430 5667777777889999**************************************99877765 PP == domain 13 score: -1.4 bits; conditional E-value: 0.062 CCDC39 687 vvnasNenyrkslskvdedseeleekkaLeeqlreaneklkekr.....eeleeleeeleeleqeleeleekeeelketleekeqeleklekei 775 +++ Ne+++++ ++ + ++ +ekk+L ql+ea++kl++ + +e+++leeele++ +e +++ +e+ +t + +++eklek FUN_001611-T1 2442 LLRGENEDLKRTADENLNHTSWETEKKKLLHQLEEAKMKLNQPKgthleAEVRRLEEELEKTRVLAAEKQKTANETLATNLRLVRKIEKLEKHG 2535 68889******9988777777788999999**********997633333678999999999999999999999999999999999999999988 PP CCDC39 776 eeqk 779 ++q FUN_001611-T1 2536 QQQG 2539 7775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2788 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4755 (0.186142); expected 510.9 (0.02) Passed bias filter: 720 (0.0281856); expected 510.9 (0.02) Passed Vit filter: 390 (0.0152672); expected 25.5 (0.001) Passed Fwd filter: 129 (0.00504991); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 5.43u 0.47s 00:00:05.90 Elapsed: 00:00:00.83 # Mc/sec: 13679.68 // Query: FUN_001612-T1 [L=798] Description: FUN_001612 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-97 326.7 40.8 1e-96 325.7 40.8 1.5 1 Mitofilin Mitochondrial inner membrane protein 0.00032 20.6 1.9 0.56 10.0 3.5 2.6 2 STING_LBD STING ligand-binding domain ------ inclusion threshold ------ 0.54 10.9 8.7 3 8.5 0.3 3.0 2 Gon7 Gon7 family Domain annotation for each model (and alignments): >> Mitofilin Mitochondrial inner membrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 325.7 40.8 1.2e-100 1e-96 13 614 .] 64 789 .. 53 789 .. 0.79 Alignments for each domain: == domain 1 score: 325.7 bits; conditional E-value: 1.2e-100 Mitofilin 13 livgvavGGvvlyakkddeFrdffeeyvPygeevvdylleedkelak.............................klktikkrqvsvvskvtkes 79 + +g v+ vv+y +++eFr ++ ++P e ++ +l+ +++ + k FUN_001612-T1 64 VCGGSVVATVVAY-HYSSEFRRLVDVNLPAIEPLLGVLDSYLNSFGNtqmpgkqqenvqefssasgpldlslpvaeK------------------- 139 5555555555555.345667777777777777666666666544333333333333222222222222222222220................... PP Mitofilin 80 kepkeekkqeks...........................................pkqsevssevaeeekeatkkeaeaka............... 117 + ++ ++++++++ e t+++++ a FUN_001612-T1 140 -----------DvplknsikpvvgnkepvasvssldqsaisavdlaiatsvekeaADSINQTENKPDTMDENTRMKQSKGAggnarspaaavsvld 224 ...........2333333344444444444444444444455555555554444333345555555555555555555555666666666667777 PP Mitofilin 118 .............................................qepkseqeaekaleevlkeaiskaesataaakeakddaieavkeatkklke 168 +++ ++ ++ + e lkea+s + ++a ea+++a a+ +++++ k+ FUN_001612-T1 225 hvgvssvdldmtasvekglgslepssmaetstdasepkeldtsltEKEIEAMVDKTSMELLLKEALSNLKVVGQDAMEAQQKAAAAIRAHVEQMKA 320 777777777777777777777777777777777777777888877888999999*****************************************9 PP Mitofilin 169 aseteeks.keka.tdsalqkaeaaa...............eelkevinaakqseeeaknplldaaeetpeklieelkeveeevekaeslallvek 247 a ++ +++ k +d++l+ ++ a ee++++ k++e + +++ +aa + ++ + +++++ +++e + +++e FUN_001612-T1 321 ALSQPQQDgMLKDlSDVLLNSQKF-AsdcvaaaktaqvlvnEEVEKLLSIIKEAEATGAKDAGTAAFAESAQVSYDVQKAALDMQQSEAEIAVLEV 415 986655541444414444454444.459**********************************************9**9999999999999999998 PP Mitofilin 248 ykelveeerqv..qeLasiipeiitvlkednk.lskdd.lnsliakAkeeldqlskklaelkkeeekkieealekkkee.ldkaaeelsarleekr 338 ++ ++ + +eL +ip++ + +d++ +k + ++ l+a A ++l+ql ++la+ ++ee+k++e++l+ +kee + + +++++ e FUN_001612-T1 416 HQKDLQDCVEAlkKELLGTIPGALAGEAADSDdEKKVRsESVLLAYARKRLEQLTQQLATFQVEEQKRLENSLKVQKEEdSKLTDLKVKQETE--- 508 8888777666678**********99988888865554415567899*******************************8844444444444444... PP Mitofilin 339 akeekqlraefereieeirekyeekLkteLerqaeaaeerLkdelveqeieLqreflqdvkekveeEragrlskLaellanlkglekalsshseve 434 + ++++++++ +++ ++++ e +L+++L+rqa+a +++L ++l++qe+eLq ++++d+++k+ eE+ ++ +L+ +la ++g+e a+++++e e FUN_001612-T1 509 -RMAAEFQTKLRTKVADLAAEHEASLRQQLRRQAAAYSDHLAEVLRVQETELQDRHNKDLQQKLNEEKSAFETQLSGALAHIRGIEAAVEGRAEIE 603 .4468******************************************************************************************* PP Mitofilin 435 denrkvqqLwlAvealrstLedasaakprPlkrelkalkelasdDevvkaaiaslpeeayqrGvyteaaLrerFrkVakevRkvslidpedaglls 530 ++n + q+Lw+A++al +++ +++a+ prPl l a+ e a+dD++v+ ++ slpeea +rGv e+ + rF++V++ R+v++i ++a+ FUN_001612-T1 604 KQNMQSQKLWAACQALTTAIGNGNAGRPRPLLPHLTAIHEAAADDPLVTQVLNSLPEEAVTRGVLNEENVKHRFYQVRRWCRRVAMIGDDGASPWT 699 *************************99********************************************************************* PP Mitofilin 531 halSyvlSkllfkekq....gel..vagdDvesiLaRaeyyLeegdLdeAaremnsLkGwskklasDWlkeaRkvlevqqalellqaeaa 614 h++Sy +S ++f+ + gel +++ D++++LaRa+yyL++gdL+ A+r +n+L+G+++k+a+DWl eaR+ le++qa++ll+a+a+ FUN_001612-T1 700 HLVSYFQSFFIFDSFEptkeGELvdFENADTFDLLARADYYLRRGDLELATRLVNQLRGEPRKVARDWLIEARLLLETRQAANLLTAYAT 789 ************965577788888****************************************************************96 PP >> STING_LBD STING ligand-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 3.5 6.6e-05 0.56 93 153 .. 502 563 .. 461 590 .. 0.81 2 ! 6.1 0.0 0.0011 9.2 46 114 .. 635 703 .. 633 708 .. 0.80 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 6.6e-05 STING_LBD 93 eednkavycvlEyAtpLltlfemsqeesaafsreerreqvklFyrtLkdiLe.dspetrnev 153 + ++++ ++ E+ t L t ++ +e++a r++ r+q+ ++ +L ++L+ ++ e +++ FUN_001612-T1 502 KVKQETERMAAEFQTKLRTKVADLAAEHEASLRQQLRRQAAAYSDHLAEVLRvQETELQDRH 563 66788999*******************************************95555666654 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0011 STING_LBD 46 iPlecevsdklekadeniefaeeleekkidraGvkkrvykhsvYkikeednkavycvlEyAtpLltlfe 114 +P+ + +++ + +++++l+e+ ++r+ +++ + kh Y+++ +++ + ++A+p l++ FUN_001612-T1 635 LPHLTAIHEAAADDPLVTQVLNSLPEEAVTRGVLNEENVKHRFYQVRRWCRRVAMIGDDGASPWTHLVS 703 566666666666555667899*************************99999999998899988776665 PP >> Gon7 Gon7 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 3.2 0.0077 65 46 104 .. 446 509 .. 438 514 .. 0.76 2 ? 8.5 0.3 0.00035 3 64 90 .. 551 577 .. 519 595 .. 0.83 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0077 Gon7 46 rdkpseakdta....aklteLseLRaqltgLQddiNefLTermeeakkkkkkved.keeeriee 104 +d ++ ++++ +++L++L +ql+++Q + + L + ++++k++ +k +d k +++ e+ FUN_001612-T1 446 SDDEKKVRSESvllaYARKRLEQLTQQLATFQVEEQKRLENSLKVQKEEDSKLTDlKVKQETER 509 44444444433666678899******************************99999855555554 PP == domain 2 score: 8.5 bits; conditional E-value: 0.00035 Gon7 64 eLRaqltgLQddiNefLTermeeakkk 90 LR q t+LQd N+ L ++++e+k++ FUN_001612-T1 551 VLRVQETELQDRHNKDLQQKLNEEKSA 577 49**********************975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (798 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2630 (0.102956); expected 510.9 (0.02) Passed bias filter: 699 (0.0273635); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.42u 0.43s 00:00:00.85 Elapsed: 00:00:00.43 # Mc/sec: 7554.27 // Query: FUN_001613-T1 [L=312] Description: FUN_001613 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-20 72.1 0.0 1.2e-19 71.3 0.0 1.4 1 UDG Uracil DNA glycosylase superfamily ------ inclusion threshold ------ 0.15 13.0 0.0 0.47 11.5 0.0 1.8 1 DUF6738 Domain of unknown function (DUF6738) Domain annotation for each model (and alignments): >> UDG Uracil DNA glycosylase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.3 0.0 9.1e-24 1.2e-19 7 140 .] 134 290 .. 129 290 .. 0.85 Alignments for each domain: == domain 1 score: 71.3 bits; conditional E-value: 9.1e-24 UDG 7 narvlivGeaPgre.edrtGlpFagrs....gnlLrnilk................eaglaregvyltnvvkcvprkptkse.......ikac.ip 73 + +v+i+G++P +++Gl+F+ + +++L ni+k +g+a++gv+l+n++++v +++++s+ +++ i+ FUN_001613-T1 134 EIKVVIIGQDPYHGpRQAHGLCFSVLPgvaiPPSLVNIYKelandidgfqipkhgyLKGWAKQGVLLLNACLTVVASKANSHkdkgweqFTDAvIR 229 789********6665666******654788899*******988888888777666644*****************9999999999****99998** PP UDG 74 yLeeqlellkpkvvvll.Gktaakallgialgkll.egl...vlplphPspllrnkskkrpalfkealedLk 140 +++ +l vv+ll G++a+k+ g+++ + + vl+ hPspl+++++ +++f++a+++Lk FUN_001613-T1 230 WINSNL----IGVVFLLwGAYAQKK------GSFIdK-KkhcVLKAVHPSPLSAHRGFLGCKHFSQANDYLK 290 ******....99************4......444432.2357**************99***********996 PP >> DUF6738 Domain of unknown function (DUF6738) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 3.7e-05 0.47 49 80 .. 119 150 .. 100 153 .. 0.84 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 3.7e-05 DUF6738 49 shsdslsvtvaseldsiqienmGeqpynGpre 80 + d s t+ e+ i++ +G++py Gpr+ FUN_001613-T1 119 TEKDVYSWTLQCEIHEIKVVIIGQDPYHGPRQ 150 567999*************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (312 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 997 (0.0390292); expected 510.9 (0.02) Passed bias filter: 779 (0.0304952); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 2984.32 // Query: FUN_001614-T1 [L=653] Description: FUN_001614 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-39 135.2 7.5 4e-39 134.7 7.5 1.2 1 Ion_trans Ion transport protein 4.3e-20 72.4 0.0 1e-19 71.1 0.0 1.7 1 BTB_2 BTB/POZ domain 6.7e-14 52.0 1.1 1.8e-13 50.6 1.1 1.8 1 Ion_trans_2 Ion channel ------ inclusion threshold ------ 0.091 13.2 0.0 0.25 11.8 0.0 1.7 1 BTB_3 BTB/POZ domain 4 9.0 6.4 1.6 10.3 1.7 2.8 3 YxzE YxzE-like putative bacteriocin Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 134.7 7.5 7.9e-43 4e-39 3 242 .. 219 448 .. 217 449 .. 0.91 Alignments for each domain: == domain 1 score: 134.7 bits; conditional E-value: 7.9e-43 Ion_trans 3 ifelfilllillntvvlaletyfqp.......eekel..klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil.ses 88 if++++ ++ ln+ +++ et + e ++++++d +++vift+e++ ++++++++++++r++ n++D++ ++p++i+ + + + FUN_001614-T1 219 IFSYVFGAVVALNISTIVAETVPTAtpgmkqvE---AhsNVFFWIDSFCVVIFTMEFIARLYSAPNRFEFVRKMSNVIDLLGIIPYYIGALErT-V 310 79999999***********99999987764333...266*************************************************998641.2 PP Ion_trans 89 ...k.eslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkkeekewenpdngrtnFdnfgnal 180 + + l++lr++r++r+ +l+r++e++++l+ s+ + +l+ +l+ +l +++ f+++++ + +d++ t+F +++ a+ FUN_001614-T1 311 ksnSaVLDFTLSILRMFRVFRVTKLARHSERFQNLLLSVRSATTELGGILFSFLALMVTFSSMMYYFE-------------KDEKGTEFISIPAAF 393 55425899*******************************************************76666.............566889********* PP Ion_trans 181 lwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqeltera 242 + +++t+tt g+gdi+++t+++k +++ + l+gvlll+l++++i ++e+ +++ FUN_001614-T1 394 WYTLVTMTTLGYGDIYPTTVKGK-------LLGAGCALIGVLLLSLPVPIIEKKLDEFGKKT 448 ***********************.......*********************88888777665 PP >> BTB_2 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.1 0.0 2e-23 1e-19 1 94 [] 74 165 .. 74 166 .. 0.94 Alignments for each domain: == domain 1 score: 71.1 bits; conditional E-value: 2e-23 BTB_2 1 vklnVgGtrfetskstLtrkpdtlLkklleteeldaydeetneyffDRspklFetiLnflrtg.gkLhepeevelkelleElefygleelalesc 94 +++nVgGt++e+ ++ L+++pdtlL++ + ++ydee+ eyffDR+p +F+ i +f+r g ++ +++ +++++l+El+f+g+ ++ + +c FUN_001614-T1 74 IVVNVGGTKYEIARKNLEKFPDTLLGSERK---NHFYDEERMEYFFDRDPLIFKNIAEFYRMGsFHVSSTTTACMEAVLDELAFFGIPPHLVCDC 165 689************************999...47***************************999999999****************99876655 PP >> Ion_trans_2 Ion channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.6 1.1 3.6e-17 1.8e-13 3 71 .. 364 435 .. 362 443 .. 0.81 Alignments for each domain: == domain 1 score: 50.6 bits; conditional E-value: 3.6e-17 Ion_trans_2 3 lllvlifgtviyll...eegwegwsfldalyfsvvtltTvGYGdivPrtdagrlftivyiliGiplfllfla 71 l l+++f+ +y++ e+g e s+ a+++++vt+tT+GYGdi+P+t g+l+ +liG++l++l + FUN_001614-T1 364 LALMVTFSSMMYYFekdEKGTEFISIPAAFWYTLVTMTTLGYGDIYPTTVKGKLLGAGCALIGVLLLSLPVP 435 445555555555555975557778******************************************988765 PP >> BTB_3 BTB/POZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 4.8e-05 0.25 2 76 .. 74 141 .. 73 165 .. 0.79 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 4.8e-05 BTB_3 2 ltlvvdetrfvvdkslftahPdtmlgrmfssslernltkpnekGeyevaegissevfraildyyktGvikcPpsv 76 +++ v +t++ + ++ ++++Pdt+lg s + +n +e+ ey ++ +f+ i ++y+ G + +++ FUN_001614-T1 74 IVVNVGGTKYEIARKNLEKFPDTLLG----SER-KNHFYDEERMEYFFDRD--PLIFKNIAEFYRMGSFHVSSTT 141 677799******************98....444.45556899999999985..78************98876654 PP >> YxzE YxzE-like putative bacteriocin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 2.1 1.1e+04 18 30 .. 22 34 .. 14 43 .. 0.40 2 ? 10.3 1.7 0.00031 1.6 25 57 .. 480 522 .. 472 523 .. 0.67 3 ? -3.1 0.0 4.9 2.5e+04 40 46 .. 592 598 .. 574 604 .. 0.59 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 2.1 YxzE 18 lavltsskskkkk 30 l+ +++++k++k FUN_001614-T1 22 LTKKMKNSRKGRK 34 2222333333333 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00031 YxzE 25 kskkkkkrss.........ydhdsssdsssDcgdssg.ggGGD 57 +s+++kkr + ++ss sss++++s+ ++G+D FUN_001614-T1 480 ASRGQKKRAQlesqttsmiVEVSNSSTSSSHSNGSFHtSFGSD 522 45555555556666654321366777899999888888****9 PP == domain 3 score: -3.1 bits; conditional E-value: 4.9 YxzE 40 ssdsssD 46 ss+ss D FUN_001614-T1 592 SSSSSGD 598 2222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (653 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1407 (0.0550793); expected 510.9 (0.02) Passed bias filter: 824 (0.0322568); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.42u 0.36s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 6183.37 // Query: FUN_001615-T1 [L=1678] Description: FUN_001615 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-33 115.9 2.7 1.3e-19 71.3 1.1 2.8 2 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamil 3e-12 47.1 0.1 5.6e-05 23.4 0.0 2.5 2 Pentaxin Pentaxin family Domain annotation for each model (and alignments): >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.9 0.0 5.6e-15 7.2e-11 72 150 .. 1335 1414 .. 1283 1415 .. 0.71 2 ! 71.3 1.1 1e-23 1.3e-19 14 150 .. 1492 1637 .. 1480 1638 .. 0.80 Alignments for each domain: == domain 1 score: 42.9 bits; conditional E-value: 5.6e-15 Laminin_G_3 72 sgasvpagqWtHvavtyd..ggtlrlYvnGeevgsstltgaltkatggply.iGrdnggdspfdGlidevriynraLsaeei 150 +vp++qW H+a+t+d +g +r+YvnG++++++ ++ + ++ + + iG++ g + f +d+v +++r+L ++e+ FUN_001615-T1 1335 KLVKVPKNQWIHLAGTFDsnDGIARVYVNGKLISERIGKRNQGLPDDFTATgIGQKFG--DKFISFLDDVFMFDRVLAPAEV 1414 4568999***********54455*************9999866655555544888877..89*******************9 PP == domain 2 score: 71.3 bits; conditional E-value: 1e-23 Laminin_G_3 14 lttsafTvsaWvkpdsapqssralvsessgg.....gyelgldsdgqlrftvnggngaee.avt.sgasvpagqWtHvavtyd..ggtlrlYvn 98 +tsa++vs W+ ++ ++++ +++ ++s+++ y+l + + g+l ++ +++n++ +v ++ +p+g W+Hv++ty+ +g ++lYvn FUN_001615-T1 1492 KPTSAISVSSWISLNRTKGRHSIFQAVSDKNdewhdIYNLDVVN-GKLHWRHKNENNGIIfNVKtQDVVIPEGLWSHVTATYNsdSGDAKLYVN 1584 4699***************8888877555555576666666644.678887777665554455536677788***********65577****** PP Laminin_G_3 99 Geevgsstltga.ltkatggplyiGrdnggdspfdGlidevriynraLsaeei 150 G +++s +++++ + + g + iG+ +++ f Gl+de+ iyn +L+++e+ FUN_001615-T1 1585 GILKASLNNANKsKLNVAWGRVSIGGHLPDARNFAGLLDEFFIYNWELNPSEV 1637 ******99988855558999999***99889*********************9 PP >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 4.4e-09 5.6e-05 81 179 .. 1340 1430 .. 1327 1442 .. 0.80 2 ! 20.8 0.1 2.7e-08 0.00034 22 171 .. 1492 1645 .. 1482 1655 .. 0.69 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 4.4e-09 Pentaxin 81 eavepvhiCasWesssGivelwvdGkplvkkslkkgytvgaeas.iilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgatls 173 + ++ h+ +++s +Gi+ ++v+Gk++ + k++ + + +Gq +G kf + l d+ ++d vL+p e++++yk ++ FUN_001615-T1 1340 PKNQWIHLAGTFDSNDGIARVYVNGKLISERIGKRNQGLPDDFTaTGIGQ---KFGDKF------ISFLDDVFMFDRVLAPAEVRMLYKKCEFN 1424 3569*************************999999988876654123344...477665......455899*********************99 PP Pentaxin 174 anildW 179 +l++ FUN_001615-T1 1425 RMVLHF 1430 999875 PP == domain 2 score: 20.8 bits; conditional E-value: 2.7e-08 Pentaxin 22 kPLknltlClrfytd.LsrsyslfsyatkkkdnelLifkekdge....yslyvggeevlvkvseeav.....epvhiCasWesssGivelwvdG 105 kP ++ + ++ + ++ +s+f k+d i+ + + + + +++ ++++v+ + v + h+ a+++s sG ++l+v+G FUN_001615-T1 1492 KPTSAISVSSWISLNrTKGRHSIFQAVSDKNDEWHDIYNLDVVNgklhWRHKNENNGIIFNVKTQDVvipegLWSHVTATYNSDSGDAKLYVNG 1585 6666666666666553446667776666665554444443333300003333444556666655555556667********************* PP Pentaxin 106 kplvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvykgat 171 + k sl+++ + + ++ G+ s+GG+ + + G l + +++ L+p e+++v+k FUN_001615-T1 1586 --ILKASLNNAN--KSKLNVAWGR--VSIGGHLPDARNFAGLLDEFFIYNWELNPSEVRFVLKYCA 1645 ..5566666544..4556677775..79*******************************9988655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1678 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1670 (0.0653748); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.61u 0.40s 00:00:01.01 Elapsed: 00:00:00.43 # Mc/sec: 15755.19 // Query: FUN_001616-T1 [L=845] Description: FUN_001616 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-60 206.0 0.0 2.2e-60 205.2 0.0 1.4 1 GPAT_C Glycerol-3-phosphate acyltransferase C-termi 5.2e-23 81.8 0.0 9.6e-23 80.9 0.0 1.4 1 Acyltransferase Acyltransferase Domain annotation for each model (and alignments): >> GPAT_C Glycerol-3-phosphate acyltransferase C-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 205.2 0.0 1.7e-64 2.2e-60 1 344 [] 400 816 .. 400 816 .. 0.91 Alignments for each domain: == domain 1 score: 205.2 bits; conditional E-value: 1.7e-64 GPAT_C 1 YakEllGkpKkkEsllgllkaarkllkenyGrvyVnFgePisLrefldeqvpdwre...........................epeeeekppwltr 69 Y+kEllG++K +Es+++ +k+++++ +++yG+v+++Fg+P+sL+ef +++ + ++ +++ FUN_001616-T1 400 YTKELLGESKTPESFWSTIKSIWRITRTRYGNVRLDFGQPFSLQEFSRSMDQSQPMkdfasnivakatvtsssrpsilrnysdVSLVDMGEEKTFA 495 9*********************************************8888777444789********************99964445555556666 PP GPAT_C 70 lvnklAyrvmrrinraavvnpvnLvalaLLatrkralteeeLvrqlewllellrargypvadtvtlsteevveralellg.kklverq.ddlledv 163 l+++l+y+v+++ ++++v+++n+va++L ++ +++ t +e+ e ll +++rg +v ++ +t++v+++al+ll+ + lv+++ ++ e++ FUN_001616-T1 496 LTKALGYHVIYDAVNCCAVMSTNMVAFLLVNNYRQGATFKEMSTSFESLLGEITSRGRDVGFSG--KTAAVIRHALRLLEdDVLVTQTqRNDCEEI 589 6***********************************************************9998..99************6666666642333443 PP GPAT_C 164 yyl....daeqavllsyYRNnilhlfvlpalvalalla..............enqrisreelleevsflypllkaEffl.wpkeeleeeleetlda 240 ++ + + l++Y N+i+ lf+l a+va+ + a ++ is+++++e+++ l+++l++Ef++ +p +le+ l e+l+ FUN_001616-T1 590 -RIepklVLPHVLNLAFYSNQIVSLFALDAVVACGIIAagddsesydtddieGKKIISQTSIIEKATYLCDILRREFIFsPPCVSLESALTEALEK 684 .331222356789*************************999887776666644444**************************************** PP GPAT_C 241 lveqglleveed.............................lspeerslgrerldflarllrpflerywlvaalLlklgpegelsrkelekecqll 307 + + ++l++ e+ + + ++++ ++l+fl+++++p +e+yw+ a Ll l++ +++s +e+++ +++ FUN_001616-T1 685 VSASEVLKRVEQrtagslgsqwgweddddddvsafdvpeveYKLAASEEELKELQFLRSVVAPLVEAYWVSACGLLWLRN-QSFSDSEFLTALHAC 779 ****************************************999999*********************************8.*************** PP GPAT_C 308 aqrlsllgglnapEffdkelfknalqtlkeegllekd 344 a++ l pE+++ e f+na++ +ke +++e+d FUN_001616-T1 780 AKERVLGEVTFFPESCSLEPFRNAIRIFKEWRVIEVD 816 *********************************9875 PP >> Acyltransferase Acyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.9 0.0 7.5e-27 9.6e-23 7 132 .] 253 391 .. 248 391 .. 0.94 Alignments for each domain: == domain 1 score: 80.9 bits; conditional E-value: 7.5e-27 Acyltransferase 7 kenlpkkgpaivvaNHqsylDvlllslalykreprnlvfvakkellklplvgtllrllgaifidR.......kskkdaakvleklvellregkl 93 ke ++++p+i+++ H+s++D++ll+++l + + r ++++a+++ l++p+++++lr+lg +fi+R k++ ++ e++++ll+++++ FUN_001616-T1 253 KEASQDDKPMIFLPLHKSHMDYILLTFVLVACDIRVPHVAAGDN-LRIPVFSWVLRHLGGFFIKRkldhssgKDELYKCLLQEYVEQLLQNQQY 345 4778899**********************99999**********.889***********************8888888888888888******* PP Acyltransferase 94 vviFPEGtrsregellpfkkGafrlavea.......gvpivPvais 132 ++++ EG rsr+g+ + +k G+++++v+a +v ivPv is FUN_001616-T1 346 LEFYIEGSRSRTGKAMVPKSGLLSVVVNAvtegvvqDVNIVPVNIS 391 *******************************************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (845 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1114 (0.0436093); expected 510.9 (0.02) Passed bias filter: 906 (0.0354668); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.43u 0.38s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 8111.05 // Query: FUN_001617-T1 [L=145] Description: FUN_001617 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-13 51.7 6.6 2e-13 51.3 6.6 1.1 1 Synaphin Synaphin protein ------ inclusion threshold ------ 0.02 15.8 0.5 0.027 15.4 0.5 1.2 1 TAF2_3rd TAF2 Ig-like domain 0.049 14.3 9.5 0.081 13.6 9.5 1.3 1 DUF3886 Protein of unknown function (DUF3886) Domain annotation for each model (and alignments): >> Synaphin Synaphin protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.3 6.6 2.4e-17 2e-13 2 119 .. 3 117 .. 2 125 .. 0.73 Alignments for each domain: == domain 1 score: 51.3 bits; conditional E-value: 2.4e-17 Synaphin 2 aFlvkqmvGnqlkdlkgglGgkggeekeeae.....mtreeeeErqealreeeeeRkekfrkmeaEReklRqeiRdKYrlkkkeedeaeiqaaeee 92 F +k +v++++ ++g +G+ gg+ +++ + t++e e ++ l e+eRk+k+ +ea ReklR++iR KY++kk+ +e ++ FUN_001617-T1 3 GFAAKHLVSSATGGMAGRVGELGGDFGKQLSmenlhLTKKEIERAEKELQRREKERKKKHIDKEASREKLRSNIRGKYGIKKRRGHEP-VE----- 92 5899***************99999988887766775556666666677888999*****************************98873.22..... PP Synaphin 93 etegrlgrkkklpeelakeveedeeee 119 g l+ + +el v++ ++e FUN_001617-T1 93 THSGILMPRSE--KELLLSVKNAGDDE 117 33566655544..34444333332222 PP >> TAF2_3rd TAF2 Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.5 3.2e-06 0.027 35 90 .. 13 71 .. 5 99 .. 0.82 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 3.2e-06 TAF2_3rd 35 ftgpltirvqEldgtyehtlqieee.vtkldiqchsk..srrqkkkkeekadgeevevd 90 tg + rv El g + ++l++e+ tk +i+ k rr+k++k++ d+e+++ + FUN_001617-T1 13 ATGGMAGRVGELGGDFGKQLSMENLhLTKKEIERAEKelQRREKERKKKHIDKEASREK 71 689999*****************9735679****9999888888877777776665544 PP >> DUF3886 Protein of unknown function (DUF3886) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 9.5 9.5e-06 0.081 12 53 .. 24 65 .. 22 75 .. 0.89 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 9.5e-06 DUF3886 12 LnsdllekLkakkseLkeeeekreeeekerrieerkereknk 53 L++d ++L L ++e +r+e+e +rr++erk++ +k FUN_001617-T1 24 LGGDFGKQLSMENLHLTKKEIERAEKELQRREKERKKKHIDK 65 899999******************************997665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (145 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2470 (0.0966921); expected 510.9 (0.02) Passed bias filter: 1122 (0.0439225); expected 510.9 (0.02) Passed Vit filter: 105 (0.00411039); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 1393.91 // Query: FUN_001618-T1 [L=362] Description: FUN_001618 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0011 18.9 0.0 0.11 12.3 0.0 2.2 2 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase ------ inclusion threshold ------ 0.15 12.7 0.0 0.34 11.6 0.0 1.5 1 DUF4581 Domain of unknown function (DUF4581) 0.27 11.5 0.0 0.43 10.9 0.0 1.2 1 MrkDrd MrkD-like receptor binding domain Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.0 1.3e-05 0.11 45 122 .. 130 212 .. 108 276 .. 0.75 2 ! 4.5 0.0 0.0029 25 231 257 .. 320 346 .. 295 347 .. 0.83 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 1.3e-05 PK_Tyr_Ser-Thr 45 keefleeaklmkkl.shpnivkllgvcteeepllivteyvegG...sLkefLrkk..keklslkellklalqiAkGmeyLeskk 122 e+ l+ +k+ + l + +v+l+g+c+ +++l +vt y ++G +L++ L++ +e +l++ ++l+++ + +++L++ FUN_001618-T1 130 YEDCLHGMKMVEGLqGSEFVVQLVGICY-SGSLELVTGYYKYGsadKLNKLLERPelSEYNTLDTRFQLCIDYVRILNFLHNSP 212 5778888899999966788*********.799***********66668888887655455566666777777777777777655 PP == domain 2 score: 4.5 bits; conditional E-value: 0.0029 PK_Tyr_Ser-Thr 231 eelyelmkeCweedpeeRptfkelvee 257 + l + ++C + dp+eRpt ke++e+ FUN_001618-T1 320 RLLLGIHESCKQDDPDERPTAKEILEN 346 556677789***************986 PP >> DUF4581 Domain of unknown function (DUF4581) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 4e-05 0.34 27 82 .. 203 265 .. 186 270 .. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4e-05 DUF4581 27 rrldfyaepgvsfyvlcpesltgg.......tdnfhvwsesedclpflqlaqdyisscgkktl 82 r l+f + + + v+c + + td+fh+ + d+lp +++ qd + cg++ l FUN_001618-T1 203 RILNFLHNSPLGVRVMCDSNDITKtlsqyliTDDFHLVVNDLDALPEVKVDQDELIKCGHREL 265 56777777778888888776554312223337***************************9987 PP >> MrkDrd MrkD-like receptor binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 5e-05 0.43 45 125 .. 93 170 .. 80 185 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 5e-05 MrkDrd 45 aeakivqpglstlgdkvYstnvaGiGlRlsrkgavaivyphelklsgselklagskftveiiKtaeqTgsGtlasGkytsY 125 + ++i pg ++ +kvY ++ +G + + k a + y + l+ + + l+gs+f+v+++ + gs l++G y Y FUN_001618-T1 93 IRRRIGIPGHLNAVKKVYLADWNGYDVV-YSKCASEMFYEDCLHGMKMVEGLQGSEFVVQLVGICY-SGSLELVTGYYK-Y 170 456777899999999********99995.556778899****99999999************9975.699999999874.5 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 567 (0.0221961); expected 510.9 (0.02) Passed bias filter: 506 (0.0198082); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.42s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3563.17 // Query: FUN_001619-T1 [L=1110] Description: FUN_001619 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-80 269.5 5.5 4.2e-80 269.5 2.1 2.7 2 Cnd3 Nuclear condensing complex subunits, C-term dom 2.8e-10 39.9 5.4 0.47 11.4 0.0 7.1 7 HEAT HEAT repeat 7.9e-08 32.3 0.9 2.2e-07 30.9 0.9 1.8 1 UVR UvrB/uvrC motif 7.1e-06 26.7 8.2 0.47 11.3 0.4 5.1 6 HEAT_2 HEAT repeats 8.3e-06 26.5 3.5 3.4e-05 24.5 3.5 2.1 1 HH_RND_rel RND related, alpha-helical hairpin domain 0.0014 19.6 5.4 0.98 10.5 0.1 4.8 5 HEAT_EZ HEAT-like repeat ------ inclusion threshold ------ 0.021 15.4 10.0 0.063 13.8 0.1 4.9 5 Cnd1 non-SMC mitotic condensation complex subunit 1 0.034 15.2 0.4 0.034 15.2 0.4 2.9 2 DUF2408 Protein of unknown function (DUF2408) 0.038 14.3 0.6 0.13 12.6 0.4 2.1 2 HEAT_Nup120 Nucleoporin Nup120, HEAT repeats 0.049 13.5 13.4 0.69 9.7 0.0 5.3 5 ARM_TBCD_2nd Tubulin-specific chaperone D-like, ARM repeats 0.14 12.9 0.6 66 4.4 0.0 4.3 4 SCD Stromalin conservative domain 1.1 9.9 5.3 4 8.2 5.3 2.0 1 ABC_tran_CTD ABC transporter C-terminal domain Domain annotation for each model (and alignments): >> Cnd3 Nuclear condensing complex subunits, C-term domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.1 0.44 9.4e+02 252 286 .. 92 131 .. 32 175 .. 0.55 2 ! 269.5 2.1 2e-83 4.2e-80 1 288 [] 566 896 .. 566 896 .. 0.96 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.44 Cnd3 252 e.....eevhldlaldilkellkkekkeekklliklLskL 286 + +++ ldl + +l ++ ++k+++ +++l++k+ FUN_001619-T1 92 DeeddaSNIFLDLIFGFLLDSHDAKDKAVRFRVCQLVNKI 131 1233344444444444444444444444444444444443 PP == domain 2 score: 269.5 bits; conditional E-value: 2e-83 Cnd3 1 kcLsivqemLenvsssleenpsleslleslilpavrskeaairelglkcLglcclldkklakenlklflqcfskgneelkitalkaifDllllhgl 96 kcL+i++emL+ v + n +l++l+++l+lp+v+++++++r++++kcLglc+ll+ ++a+++l lflq+++ ++e +++tal+++fDlll++gl FUN_001619-T1 566 KCLTIASEMLQGVA-TSGLNATLTTLVQTLVLPGVQNEDPSVRNMAVKCLGLCALLSCEFARTHLVLFLQVAQLDQELVRVTALQVVFDLLLTFGL 660 8*************.********************************************************************************* PP Cnd3 97 elldkekkvdseese.es...............................................ssksllklllkaLkseenpevqavaaeglcK 144 e ++ + + ++ e ++ + s+l++l+ +L+se +++++ vaaegl+K FUN_001619-T1 661 EAFKVKASLPEQ--ElSNvggassseqdsseeeeskedegdeandsdceheadgdadetqapvvdTAASVLTILTGILESE-SNDLRNVAAEGLAK 753 ***887665554..3333667889999****************************************************99.6************* PP Cnd3 145 LllagiltdselLsrLvllyfnpeteenqrLrQcLsvffpvYaysspenqerlaeiflptlrtlleapdesplaeemvspsqvlkqlvdwtdprkl 240 Lll+g++ + +l+ rL+ll++np+te++ Lr+cL+vffpv+a+ s++nqe+++e+flptl+tl++ap +spla +v++++v+++lv++t+ + l FUN_001619-T1 754 LLLSGRVLSAKLFVRLLLLWYNPTTEDDVNLRHCLGVFFPVFAFASRTNQELVEEAFLPTLQTLFSAPVSSPLA--SVNINNVAELLVELTNSKYL 847 *******999****************************************************************..******************** PP Cnd3 241 vnkaeeeeskse.eevhldlaldilkellkkekkeekklliklLskLei 288 +k+ ++++++e +++h++l l + +e+l+++ ++ +++l+k+L+++++ FUN_001619-T1 848 TKKTANSIDTTEvASIHVSLSLAVANEILSNPWAPGVRVLCKILTMMDL 896 **********99*99*****************************99875 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.93 2e+03 4 30 .. 108 134 .. 105 135 .. 0.77 2 ! 10.7 0.0 0.00036 0.76 1 27 [. 149 175 .. 149 177 .. 0.90 3 ! 8.1 0.0 0.0024 5.1 2 24 .. 186 209 .. 185 214 .. 0.83 4 ? -0.0 0.0 1 2.2e+03 3 25 .. 217 239 .. 215 240 .. 0.82 5 ? -3.1 0.0 9.9 2.1e+04 3 14 .. 254 265 .. 253 267 .. 0.81 6 ! 11.4 0.0 0.00022 0.47 4 25 .. 594 615 .. 591 619 .. 0.89 7 ? 3.5 0.0 0.075 1.6e+02 2 28 .. 729 755 .. 728 757 .. 0.87 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.93 HEAT 4 lllkllnDpspeVReaAaeaLgalaev 30 +ll ++ VR +++ + +++ + FUN_001619-T1 108 FLLDSHDAKDKAVRFRVCQLVNKILNN 134 566655668999********9999876 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00036 HEAT 1 llplllkllnDpspeVReaAaeaLgal 27 ++ ++l+ l+D+ p VR +A+ a+++l FUN_001619-T1 149 IFETMLTRLHDKIPAVRVQAVAAVSRL 175 57789999***************9998 PP == domain 3 score: 8.1 bits; conditional E-value: 0.0024 HEAT 2 lplllkll.nDpspeVReaAaeaL 24 +++ l+l+ +D+s+eVR+a++ ++ FUN_001619-T1 186 ISTYLSLMsTDSSAEVRRAVLLNI 209 566778877***********9877 PP == domain 4 score: -0.0 bits; conditional E-value: 1 HEAT 3 plllkllnDpspeVReaAaeaLg 25 +++ +D ++VR+ A + L+ FUN_001619-T1 217 EAIIGRTQDVTESVRKLAYRILA 239 67888899********9987775 PP == domain 5 score: -3.1 bits; conditional E-value: 9.9 HEAT 3 plllkllnDpsp 14 +ll+++l+D s+ FUN_001619-T1 254 QLLCNGLRDRSE 265 6899*****987 PP == domain 6 score: 11.4 bits; conditional E-value: 0.00022 HEAT 4 lllkllnDpspeVReaAaeaLg 25 l+l + + ++p+VR +A+++Lg FUN_001619-T1 594 LVLPGVQNEDPSVRNMAVKCLG 615 5788999**************9 PP == domain 7 score: 3.5 bits; conditional E-value: 0.075 HEAT 2 lplllkllnDpspeVReaAaeaLgala 28 l +l l+++s + R Aae L++l+ FUN_001619-T1 729 LTILTGILESESNDLRNVAAEGLAKLL 755 66777789***************9986 PP >> UVR UvrB/uvrC motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.9 1e-10 2.2e-07 3 36 .] 505 538 .. 504 538 .. 0.96 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 1e-10 UVR 3 likeLeeemeeAaenedFErAAklRDqinalekq 36 ++++L++e+e+++ n+dF rAA+l+ +i+ le+q FUN_001619-T1 505 KLNQLRDELEQCVTNQDFTRAAELKQEITDLEEQ 538 699****************************997 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 2.4 5.1e+03 42 58 .. 115 131 .. 77 147 .. 0.69 2 ! 11.3 0.4 0.00022 0.47 31 84 .. 148 206 .. 108 209 .. 0.68 3 ! 9.4 0.3 0.00086 1.8 5 74 .. 190 263 .. 186 275 .. 0.80 4 ? 2.7 0.1 0.1 2.2e+02 10 71 .. 224 294 .. 213 306 .. 0.70 5 ! 7.4 0.0 0.0036 7.6 36 56 .. 595 615 .. 563 649 .. 0.79 6 ? 2.6 0.1 0.11 2.4e+02 63 88 .] 728 752 .. 723 765 .. 0.67 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 2.4 HEAT_2 42 dedpavRraaakaLgki 58 +d+avR+ +++ ki FUN_001619-T1 115 AKDKAVRFRVCQLVNKI 131 36788888888766665 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00022 HEAT_2 31 ealpaLlellkdedpavRraaakaLgkigdpe.....alpaLlelladddddvvraaaa 84 ++ +++l l+d+ pavR +a+ a ++++dp +++ l l+ +d++++vr+a++ FUN_001619-T1 148 RIFETMLTRLHDKIPAVRVQAVAAVSRLQDPGdtecpVISTYLSLMSTDSSAEVRRAVL 206 56778888888888888888888888887655444556666666777777777777754 PP == domain 3 score: 9.4 bits; conditional E-value: 0.00086 HEAT_2 5 lqaLlkdpdpevraaairaLgeigdpealpaLlellkdedpavRraaakaLg...kigd...pealpaLlelladd 74 l+++++d++ evr+a++ ++ ++++l+a++ +d + vR+ a++ L+ i++ + +++L l+d FUN_001619-T1 190 LSLMSTDSSAEVRRAVLLNIA--ISAQTLEAIIGRTQDVTESVRKLAYRILAekvNIKSftiAQRVQLLCNGLRDR 263 678889**************8..66679***********************9544455555566777777777665 PP == domain 4 score: 2.7 bits; conditional E-value: 0.1 HEAT_2 10 kdpdpevraaairaLg...eigdp...ealpaLlellkdedpavRraaakaL..gkigd.pealpaLlell 71 +d + vr+ a r+L+ +i++ + +++L + l+d ++a+ +ak L ++++ ++++ Ll+ l FUN_001619-T1 224 QDVTESVRKLAYRILAekvNIKSFtiaQRVQLLCNGLRDRSEAINNICAKELlgNWLKSfDKDIIKLLKSL 294 56677899999999996553333122255999999999999999888888885447777666666666666 PP == domain 5 score: 7.4 bits; conditional E-value: 0.0036 HEAT_2 36 LlellkdedpavRraaakaLg 56 +l +++edp vR +a+k+Lg FUN_001619-T1 595 VLPGVQNEDPSVRNMAVKCLG 615 455678899999999999887 PP == domain 6 score: 2.6 bits; conditional E-value: 0.11 HEAT_2 63 alpaLlelladddddvvraaaaeaLa 88 +l +L+ +l+++++d+ r+ aae La FUN_001619-T1 728 VLTILTGILESESNDL-RNVAAEGLA 752 4556666665555554.666666554 PP >> HH_RND_rel RND related, alpha-helical hairpin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 3.5 1.6e-08 3.4e-05 15 86 .. 483 553 .. 481 558 .. 0.95 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.6e-08 HH_RND_rel 15 IeelknkekeeelfekdiekldeeIdklikeiqkkikegdyekieelKeeLssllekkkiisgekslsgknl 86 Ie+ +nk +++ l e i ++ ++++l +e+ + ++++d+ ++ elK+e+ l e+k+++ +e++++++++ FUN_001619-T1 483 IETAQNK-EKKRLWELKIAGIHVKLNQLRDELEQCVTNQDFTRAAELKQEITDLEEQKETLDSEENFFSQTV 553 8899997.999*********************************************************9987 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.2 0.005 11 1 48 [. 162 205 .. 162 207 .. 0.80 2 ? -3.0 0.0 8.1 1.7e+04 26 41 .. 249 264 .. 229 267 .. 0.54 3 ! 10.5 0.1 0.00046 0.98 9 53 .. 568 615 .. 567 616 .. 0.91 4 ? -0.8 0.0 1.6 3.4e+03 23 53 .. 722 752 .. 714 754 .. 0.75 5 ? -2.8 0.0 7.2 1.5e+04 14 48 .. 899 928 .. 894 928 .. 0.84 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.005 HEAT_EZ 1 wrvReaAalaLGslaeggpdllapllpellplLlplLnddddeVReaA 48 + vR A++a+++l+++g + + +L + +d+++eVR a+ FUN_001619-T1 162 PAVRVQAVAAVSRLQDPGDTECP----VISTYLSLMSTDSSAEVRRAV 205 689********888866666555....888888888899999**9886 PP == domain 2 score: -3.0 bits; conditional E-value: 8.1 HEAT_EZ 26 lpellplLlplLnddd 41 + + + lL++ L+d + FUN_001619-T1 249 IAQRVQLLCNGLRDRS 264 4456667777777765 PP == domain 3 score: 10.5 bits; conditional E-value: 0.00046 HEAT_EZ 9 laLGs..laeggpdllapllpellplLl.plLnddddeVReaAawaLg 53 l+++s l+++ l+ l+ l+ +L+ p +++d++VR+ A+ +Lg FUN_001619-T1 568 LTIASemLQGVATSGLNATLTTLVQTLVlPGVQNEDPSVRNMAVKCLG 615 56777789999999*********************************9 PP == domain 4 score: -0.8 bits; conditional E-value: 1.6 HEAT_EZ 23 apllpellplLlplLnddddeVReaAawaLg 53 + + +l L+ +L++++++ R+ Aa L+ FUN_001619-T1 722 VDTAASVLTILTGILESESNDLRNVAAEGLA 752 4566778889999999999999987777666 PP == domain 5 score: -2.8 bits; conditional E-value: 7.2 HEAT_EZ 14 laeggpdllapllpellplLlplLnddddeVReaA 48 +a+++ + ++ l ++++++ + d+ +VR ++ FUN_001619-T1 899 CAQSNIKEMKILTTRMMEEIE-----DSVSVRTLT 928 6778888899999999*9999.....999999875 PP >> Cnd1 non-SMC mitotic condensation complex subunit 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.2 1.3 2.7e+03 78 134 .. 22 80 .. 13 85 .. 0.70 2 ? 13.8 0.1 3e-05 0.063 16 78 .. 143 205 .. 139 214 .. 0.85 3 ? 2.1 0.1 0.12 2.5e+02 23 88 .. 216 281 .. 210 315 .. 0.75 4 ? -0.1 0.0 0.55 1.2e+03 30 45 .. 599 614 .. 583 628 .. 0.84 5 ? -0.5 0.0 0.72 1.5e+03 26 65 .. 732 771 .. 722 779 .. 0.78 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.3 Cnd1 78 alaalteiseksenaiynllpdi.isklsdalnecs.ewgqktileaLlsyipkdkqea 134 ++ +lte+++ ++n + +++ + +l++a+ ++ e + ++++e+ ++y++ +++ a FUN_001619-T1 22 SKKLLTELKKLHDNSTQDEFQESfLLHLKHAMVVFNrESTVERVIEFAAKYVTLKEHRA 80 66788999998666666666554155777776666515667889999999998887766 PP == domain 2 score: 13.8 bits; conditional E-value: 3e-05 Cnd1 16 pnlveylvepLrkrLkDedpyVRktAaivvakLilndmvkvkgflselaklLeDenprVvana 78 ++l + + e + +rL+D+ p VR +A+ +v++L +++ + + l + +D++++V+ + FUN_001619-T1 143 DKLADRIFETMLTRLHDKIPAVRVQAVAAVSRLQDPGDTECPVISTYLSLMSTDSSAEVRRAV 205 5789999**************************999988877777777777789988888665 PP == domain 3 score: 2.1 bits; conditional E-value: 0.12 Cnd1 23 vepLrkrLkDedpyVRktAaivvakLilndmvkvkgflselaklLeDenprVvanalaalteisek 88 +e + r +D VRk A ++a+ ++ + + + ++ l + L+D ++ + +++ l + k FUN_001619-T1 216 LEAIIGRTQDVTESVRKLAYRILAEKVNIKSFTIAQRVQLLCNGLRDRSEAINNICAKELLGNWLK 281 566667789999999999999999999999999999999999999999999999887655544444 PP == domain 4 score: -0.1 bits; conditional E-value: 0.55 Cnd1 30 LkDedpyVRktAaivv 45 ++ edp VR A+ ++ FUN_001619-T1 599 VQNEDPSVRNMAVKCL 614 6789999999999997 PP == domain 5 score: -0.5 bits; conditional E-value: 0.72 Cnd1 26 LrkrLkDedpyVRktAaivvakLilndmvkvkgflselak 65 L+ L+ e+ R Aa ++akL+l + v + +++ +l FUN_001619-T1 732 LTGILESESNDLRNVAAEGLAKLLLSGRVLSAKLFVRLLL 771 5556777888899**********99998888886666655 PP >> DUF2408 Protein of unknown function (DUF2408) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.2 1.5 3.1e+03 38 61 .. 22 48 .. 7 100 .. 0.60 2 ? 15.2 0.4 1.6e-05 0.034 9 70 .. 500 560 .. 495 590 .. 0.78 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.5 DUF2408 38 lkelkkeLkeieskrde...egkfass 61 k+l +eLk++ ++ + ++ f + FUN_001619-T1 22 SKKLLTELKKLHDNSTQdefQESFLLH 48 344555555555444443344444433 PP == domain 2 score: 15.2 bits; conditional E-value: 1.6e-05 DUF2408 9 epiyekLvsirrsllslatrskkeskkeelkelkkeLkeieskrdeegkfassetkevvekg 70 i+ kL ++r +l +++t+++++ +++elk+ ++L+e +++ d+e++f s+ ++ +++ FUN_001619-T1 500 AGIHVKLNQLRDELEQCVTNQDFT-RAAELKQEITDLEEQKETLDSEENFFSQTVRSEEKDD 560 56899******************8.788888888888888888888****999774444433 PP >> HEAT_Nup120 Nucleoporin Nup120, HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.4 6.2e-05 0.13 41 110 .. 4 71 .. 2 113 .. 0.82 2 ? -3.8 0.0 6.6 1.4e+04 22 35 .. 373 387 .. 369 391 .. 0.77 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 6.2e-05 HEAT_Nup120 41 efdeAaelFkkaayglsgkdsaesdedseglldvlepnalnsglpkYYahvasLfekakaysyvaefarl 110 ++d ++F++a gl +++++ ++ ++l+d +++++++ h++ f +++ + v+efa FUN_001619-T1 4 RYDSVRSIFEEAQRGL-QHSKK-LLTELKKLHDNSTQDEFQESFLLHLKHAMVVFNRESTVERVIEFAAK 71 6777889*********.44333.33359***************************************976 PP == domain 2 score: -3.8 bits; conditional E-value: 6.6 HEAT_Nup120 22 lpe.tpwstYvkGrl 35 lpe + ++tY++G + FUN_001619-T1 373 LPEvSGFCTYIQGYV 387 5655889*****976 PP >> ARM_TBCD_2nd Tubulin-specific chaperone D-like, ARM repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.0039 8.2 49 124 .. 77 153 .. 41 174 .. 0.65 2 ? 4.0 0.1 0.018 39 66 131 .. 136 200 .. 114 215 .. 0.73 3 ? 1.6 0.1 0.1 2.2e+02 112 161 .. 271 323 .. 222 328 .. 0.71 4 ? -1.3 0.0 0.77 1.6e+03 80 114 .. 593 626 .. 523 641 .. 0.76 5 ? 9.7 0.0 0.00033 0.69 36 105 .. 686 755 .. 676 789 .. 0.73 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0039 ARM_TBCD_2nd 49 eeaeeaakeeeeeeeeeeedlevpeeveeviellleglkdkdtvvrwsaAkgigritsrLpke..ladevvesvlelf 124 e+++ a ++ +++++eed + ++ + ll++ kd++vr+ + + +i + L + + d++ + ++e++ FUN_001619-T1 77 EHRAV-AIQKGGQHSDDEEDDASNIFLDLIFGFLLDSHDAKDKAVRFRVCQLVNKILNNLDDDavIDDKLADRIFETM 153 22222.333333444444555556678999***************************999876222344455555544 PP == domain 2 score: 4.0 bits; conditional E-value: 0.018 ARM_TBCD_2nd 66 eedlevp.eeveeviellleglkdkdtvvrwsaAkgigritsrLpkeladevvesvlelfsekesds 131 ++d+ ++ + +++ e++l+ l+dk +vr a +++r+ p ++ v+++ l+l+s+++s + FUN_001619-T1 136 DDDAVIDdKLADRIFETMLTRLHDKIPAVRVQAVAAVSRLQD--PGDTECPVISTYLSLMSTDSSAE 200 344444404568999************************976..55555567777777777666655 PP == domain 3 score: 1.6 bits; conditional E-value: 0.1 ARM_TBCD_2nd 112 ladevvesvlelfsekes...dsawhGgcLalAeLarrglllperLpevvpvv 161 +a+e++++ l+ f+++ +s gc +AeLa +g+l +++++++ + FUN_001619-T1 271 CAKELLGNWLKSFDKDIIkllKSLDVEGCTEVAELAVKGILKGLTVEDLLEHI 323 55555555555555543211123334689999999999999888777777665 PP == domain 4 score: -1.3 bits; conditional E-value: 0.77 ARM_TBCD_2nd 80 ellleglkdkdtvvrwsaAkgigritsrLpkelad 114 +l+l g++++d vr a k +g +++ L+ e+a+ FUN_001619-T1 593 TLVLPGVQNEDPSVRNMAVKCLG-LCALLSCEFAR 626 34578999999999999999998.56667777666 PP == domain 5 score: 9.7 bits; conditional E-value: 0.00033 ARM_TBCD_2nd 36 enlkkeskkkeaeeeaeeaakeeeeeeeeeeedlevpeeveeviellleglkdkdtvvrwsaAkgigrit 105 ++ ++e++k+++ +ea+++ e+e+ +++e+++ v ++ +v++ l l+++++ +r aA g++++ FUN_001619-T1 686 DSSEEEESKEDEGDEANDSDCEHEADGDADETQAPVVDTAASVLTILTGILESESNDLRNVAAEGLAKLL 755 333444445555555556666667777777888889999999************************9986 PP >> SCD Stromalin conservative domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.031 66 38 58 .. 156 176 .. 145 182 .. 0.87 2 ? 1.6 0.0 0.22 4.7e+02 34 55 .. 189 210 .. 186 231 .. 0.82 3 ? 1.1 0.0 0.31 6.6e+02 1 24 [. 261 285 .. 261 289 .. 0.84 4 ? -2.6 0.0 4.4 9.4e+03 43 54 .. 603 614 .. 600 650 .. 0.64 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.031 SCD 38 lLsDksaevRlealkaLqkly 58 L+Dk ++vR +a+ a+++l FUN_001619-T1 156 RLHDKIPAVRVQAVAAVSRLQ 176 59**************99985 PP == domain 2 score: 1.6 bits; conditional E-value: 0.22 SCD 34 YlgwlLsDksaevRlealkaLq 55 Yl + +D+saevR+++l + FUN_001619-T1 189 YLSLMSTDSSAEVRRAVLLNIA 210 999999**********997765 PP == domain 3 score: 1.1 bits; conditional E-value: 0.31 SCD 1 rDvdpeIRaeciee.lgeWikkype 24 rD + I +c +e lg+W+k++ + FUN_001619-T1 261 RDRSEAINNICAKElLGNWLKSFDK 285 899999******99459***99865 PP == domain 4 score: -2.6 bits; conditional E-value: 4.4 SCD 43 saevRlealkaL 54 +++vR a+k L FUN_001619-T1 603 DPSVRNMAVKCL 614 456666666654 PP >> ABC_tran_CTD ABC transporter C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 5.3 0.0019 4 5 60 .. 489 542 .. 486 545 .. 0.88 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0019 ABC_tran_CTD 5 keqreleeleaeIekLEeeiaeleaqladpelysdyeklaelsaeleeleeeleel 60 ke+++l e +I+ + ++ +l ++l++ +d++++ael +e+++lee+ e+l FUN_001619-T1 489 KEKKRL--WELKIAGIHVKLNQLRDELEQCVTNQDFTRAAELKQEITDLEEQKETL 542 777776..5779****************99888999****************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1945 (0.0761401); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 88 (0.0034449); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.54u 0.37s 00:00:00.91 Elapsed: 00:00:00.42 # Mc/sec: 10545.88 // Query: FUN_001620-T1 [L=176] Description: FUN_001620 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (176 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 527 (0.0206303); expected 510.9 (0.02) Passed bias filter: 455 (0.0178117); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1756.79 // Query: FUN_001621-T1 [L=224] Description: FUN_001621 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-28 96.6 10.2 1.4e-27 95.9 10.2 1.3 1 TB2_DP1_HVA22 TB2/DP1, HVA22 family ------ inclusion threshold ------ 0.21 11.8 3.8 0.52 10.5 3.8 1.7 1 DUF6768 Family of unknown function (DUF6768) Domain annotation for each model (and alignments): >> TB2_DP1_HVA22 TB2/DP1, HVA22 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.9 10.2 1.1e-31 1.4e-27 1 77 [] 19 96 .. 19 96 .. 0.97 Alignments for each domain: == domain 1 score: 95.9 bits; conditional E-value: 1.1e-31 TB2_DP1_HVA22 1 PayasykaleskdkkddtqwltYWvvfalltlveslldllls.wiPfYyelKllfllwlvlpqtkgasyiYekflrpl 77 Payasyka+++k+ +++ +w++YW+vfal++++e ++dl++ w+PfYyelK++f+lwl+lp kg+s++Y+kf++p+ FUN_001621-T1 19 PAYASYKAMKTKNVREYVRWMMYWIVFALFITAELFADLIFGfWFPFYYELKIIFMLWLLLPASKGSSVLYRKFVHPW 96 9**************999*******************999988*********************************96 PP >> DUF6768 Family of unknown function (DUF6768) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 3.8 4.1e-05 0.52 48 88 .. 9 49 .. 1 54 [. 0.77 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 4.1e-05 DUF6768 48 nivqivffvlfvycavqffqaeevnelikWgvgalvlllvv 88 +i+ + ++ +y+ ++++++++v+e ++W+++ +v+ l++ FUN_001621-T1 9 VIMLVFGTLYPAYASYKAMKTKNVREYVRWMMYWIVFALFI 49 455555566679********************999988776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1098 (0.042983); expected 510.9 (0.02) Passed bias filter: 645 (0.0252496); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 2294.05 // Query: FUN_001622-T1 [L=454] Description: FUN_001622 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-07 32.1 0.0 0.00052 20.0 0.0 2.2 2 ARM_ARMC5 ARMC5 4.5e-07 31.3 1.5 4.1e-06 28.2 1.4 2.8 1 Fes1 Nucleotide exchange factor Fes1 3.2e-05 24.8 0.7 0.00016 22.6 0.7 2.4 2 HEAT_EZ HEAT-like repeat 0.00065 20.4 0.2 0.003 18.3 0.2 2.2 1 HEAT_2 HEAT repeats 0.00092 19.7 0.6 0.22 12.4 0.1 4.1 4 HEAT HEAT repeat 0.0013 19.2 1.0 0.013 16.0 0.1 2.7 3 Arm Armadillo/beta-catenin-like repeat ------ inclusion threshold ------ 0.027 14.9 1.1 2 8.8 0.2 3.2 3 HEAT_EF3_N EF3 N-terminal HEAT repeat 0.16 12.5 0.7 0.53 10.9 0.1 2.1 2 DUF1836 Domain of unknown function (DUF1836) Domain annotation for each model (and alignments): >> ARM_ARMC5 ARMC5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 1.6e-07 0.00052 24 153 .. 215 348 .. 207 361 .. 0.81 2 ! 9.9 0.1 0.0002 0.63 105 182 .. 365 445 .. 361 449 .. 0.76 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 1.6e-07 ARM_ARMC5 24 rklggisalvsilksvkkd..SiqnRacRligNLAed.kenaealheagvvpalvellketedsetlqmavRalriLwd.tkekreeilesgavra 115 r+l+ i l+ ++k +++ S+ +Ra+ ++g A++ +++ +a ++ ++ p l++ll++++ ++ ++ a+ al L ++ ++e l+ +++ FUN_001622-T1 215 RDLHSIGGLALVIKLMNSTepSLASRASYVLGSAAQSnPQVQQAALKLEALPLLLRLLSKDKPMAVRKKALYALSSLIRlFPIGQKEFLKFSGLDI 310 455556666666666554335**************97267888899*******************************9956999************ PP ARM_ARMC5 116 vaellsseeeealvkavlkalaeltkgcseecaeqvqe 153 +l++ ++e l +++ + ++ ++ e++ + +++ FUN_001622-T1 311 FQKLFEEPSSEPLLVKAITLMTDILTEQFEHVRNRLEK 348 ******99999998888888888877776666666654 PP == domain 2 score: 9.9 bits; conditional E-value: 0.0002 ARM_ARMC5 105 eeilesgavravaellsseeeealvkavlkalaeltkgcseecaeqvqegkg....lkelvslasekkksikelalkvllnl 182 ++++e+g r v ll ++ e++ +++vl+al+ + +gc++e+ e ++++ l+ l++ ++++++ + +++ll l FUN_001622-T1 365 KKMVEKGWCRLVPGLLHTT-ENDTKEKVLQALHVMATGCKSEFQEAHVQDNLnrlkLEWLKDASQHHQDHDDSEYVRILLGL 445 689**************95.6799*****************99988544321122266667777777666666666666655 PP >> Fes1 Nucleotide exchange factor Fes1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 1.4 1.3e-09 4.1e-06 16 89 .] 141 217 .. 114 217 .. 0.76 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 1.3e-09 Fes1 16 sdetkekeaaaeakkeeeldp..elldal....lggpsdaelmkealevledeevsledklealdnleqlvesiDnANnL 89 +++++ +++++++k ++ld+ ++ l l + d+e + e ++vl++++++l +k+ al++le v +iDnA +L FUN_001622-T1 141 DSSEELGSRLESSQKFRSLDEiqKE---LegvdLFVKKDIEVIMEYVAVLNSSSSNLSEKEYALNELEYNVHQIDNARDL 217 3333444444444444666543333...344487789****************************************997 PP >> HEAT_EZ HEAT-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.7 5.1e-08 0.00016 7 55 .] 241 291 .. 223 291 .. 0.88 2 ? -2.8 0.0 4.8 1.5e+04 4 21 .. 388 405 .. 375 414 .. 0.62 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 5.1e-08 HEAT_EZ 7 AalaLGslaeggpdllapllp.ellplLlplLndddd.eVReaAawaLgrl 55 A ++LGs a+++p++ + +l+ e+lplLl+lL+ d++ +VR++A++aL+ l FUN_001622-T1 241 ASYVLGSAAQSNPQVQQAALKlEALPLLLRLLSKDKPmAVRKKALYALSSL 291 7789**************88769999999***555555**********976 PP == domain 2 score: -2.8 bits; conditional E-value: 4.8 HEAT_EZ 4 ReaAalaLGs.laeggpdl 21 +e + aL +a g++ FUN_001622-T1 388 KEKVLQAL-HvMATGCKSE 405 44555566.4466666555 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.2 9.4e-07 0.003 4 58 .. 226 291 .. 223 304 .. 0.80 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 9.4e-07 HEAT_2 4 LlqaLlkdpdpevraaairaLg..eigdp.........ealpaLlell.kdedpavRraaakaLgki 58 +++++ ++++p + +a +Lg ++p ealp+Ll+ll kd+ avR+ a+ aL+++ FUN_001622-T1 226 VIKLM-NSTEPSLASRASYVLGsaAQSNPqvqqaalklEALPLLLRLLsKDKPMAVRKKALYALSSL 291 45555.9***************662333368888999999********5555568*********975 PP >> HEAT HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.23 7.3e+02 4 28 .. 225 249 .. 223 252 .. 0.84 2 ? 0.4 0.0 0.52 1.7e+03 12 22 .. 251 261 .. 242 262 .. 0.81 3 ! 12.4 0.1 6.9e-05 0.22 2 29 .. 265 293 .. 264 295 .. 0.91 4 ? -0.9 0.0 1.3 4.3e+03 5 28 .. 379 399 .. 375 402 .. 0.51 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.23 HEAT 4 lllkllnDpspeVReaAaeaLgala 28 l++kl+n+++p+ A + Lg+ a FUN_001622-T1 225 LVIKLMNSTEPSLASRASYVLGSAA 249 689*********9999999998755 PP == domain 2 score: 0.4 bits; conditional E-value: 0.52 HEAT 12 pspeVReaAae 22 ++p+V +aA++ FUN_001622-T1 251 SNPQVQQAALK 261 79*******97 PP == domain 3 score: 12.4 bits; conditional E-value: 6.9e-05 HEAT 2 lplllkll.nDpspeVReaAaeaLgalae 29 lplll+ll +D+ VR+ A++aL++l++ FUN_001622-T1 265 LPLLLRLLsKDKPMAVRKKALYALSSLIR 293 8*******9999999**********9986 PP == domain 4 score: -0.9 bits; conditional E-value: 1.3 HEAT 5 llkllnDpspeVReaAaeaLgala 28 ll+ + + +e +++aL +a FUN_001622-T1 379 LLHTT---ENDTKEKVLQALHVMA 399 44443...4444555666666555 PP >> Arm Armadillo/beta-catenin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.35 1.1e+03 12 32 .. 221 241 .. 221 248 .. 0.83 2 ! 16.0 0.1 4.1e-06 0.013 1 39 [. 252 291 .. 252 293 .. 0.93 3 ? -3.2 0.0 4.6 1.5e+04 20 36 .. 379 395 .. 375 398 .. 0.75 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.35 Arm 12 GavppLvrLLsspdeevqeeA 32 G++ ++L++s+ +++ + A FUN_001622-T1 221 GGLALVIKLMNSTEPSLASRA 241 889999*******99987766 PP == domain 2 score: 16.0 bits; conditional E-value: 4.1e-06 Arm 1 spenkqavieaGavppLvrLLs.spdeevqeeAawALsNL 39 +p+ qa +++ a+p L+rLLs ++ v++ A+ ALs L FUN_001622-T1 252 NPQVQQAALKLEALPLLLRLLSkDKPMAVRKKALYALSSL 291 678889999****************************988 PP == domain 3 score: -3.2 bits; conditional E-value: 4.6 Arm 20 LLsspdeevqeeAawAL 36 LL+++ +++e ++ AL FUN_001622-T1 379 LLHTTENDTKEKVLQAL 395 77888888888777666 PP >> HEAT_EF3_N EF3 N-terminal HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.2 0.00063 2 9 86 .. 184 260 .. 176 265 .. 0.84 2 ? 1.2 0.0 0.14 4.5e+02 65 95 .. 263 294 .. 260 305 .. 0.78 3 ? 1.4 0.0 0.12 4e+02 57 98 .. 318 359 .. 310 410 .. 0.60 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00063 HEAT_EF3_N 9 asfvkgngieslkpekilealkkalknkksaaaalgavaaiaseselspsvEPylvellpellelvgDkkkevkeaae 86 ++++++ + +e +l++l+ ++++ ++ a+ l + +a +l +s+EP l++ + +l ++ ++ +v++aa FUN_001622-T1 184 VAVLNSSSSNLSEKEYALNELEYNVHQIDN-ARDLHSIGGLALVIKLMNSTEPSLASRASYVLGSAAQSNPQVQQAAL 260 566777777777778888888888877776.578888999999999******************************96 PP == domain 2 score: 1.2 bits; conditional E-value: 0.14 HEAT_EF3_N 65 ellpellelvg.Dkkkevkeaaeeaakaivka 95 e lp ll l++ Dk +v+++a a+ ++++ FUN_001622-T1 263 EALPLLLRLLSkDKPMAVRKKALYALSSLIRL 294 56777777776589999999999998888775 PP == domain 3 score: 1.4 bits; conditional E-value: 0.12 HEAT_EF3_N 57 psvEPylvellpellelvgDkkkevkeaaeeaakaivkainp 98 ps EP lv+ ++ + + + ++ ++v++ e+ + + +i+ FUN_001622-T1 318 PSSEPLLVKAITLMTDILTEQFEHVRNRLEKQGQDVSGEISG 359 778999999888888888888888888877776666665554 PP >> DUF1836 Domain of unknown function (DUF1836) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 0.00017 0.53 44 95 .. 85 137 .. 79 147 .. 0.83 2 ? -2.6 0.1 2.6 8.2e+03 5 30 .. 165 190 .. 162 205 .. 0.67 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00017 DUF1836 44 vKekliskpkk.KkYskeqiaelilisllksvlsleeikkllklaleeiedee 95 vKe +++ ++ KkY+ + ++ +i+ k+v+s +++k++lk +++++++++ FUN_001622-T1 85 VKEAKLMDGDDgKKYQSNGNTKQKFIKIDKNVISKQHLKEALKDFRDKFHHDS 137 787666666666**********************************9988776 PP == domain 2 score: -2.6 bits; conditional E-value: 2.6 DUF1836 5 elPeidLyldqvielinkkleslkrt 30 el +dL++ + ie+i ++++ l+++ FUN_001622-T1 165 ELEGVDLFVKKDIEVIMEYVAVLNSS 190 56667777777777777777665553 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (454 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1200 (0.0469759); expected 510.9 (0.02) Passed bias filter: 625 (0.0244666); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4363.22 // Query: FUN_001623-T1 [L=243] Description: FUN_001623 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (243 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 513 (0.0200822); expected 510.9 (0.02) Passed bias filter: 425 (0.0166373); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2381.55 // Query: FUN_001624-T1 [L=563] Description: FUN_001624 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-36 124.2 31.2 4.6e-28 98.5 21.7 2.1 2 Ion_trans Ion transport protein 5.9e-05 23.1 29.7 0.078 12.9 0.1 4.3 4 PKD_channel Polycystin cation channel Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 2.0 1.1e-11 1.4e-07 165 235 .. 35 103 .. 1 107 [. 0.81 2 ! 98.5 21.7 3.6e-32 4.6e-28 2 240 .. 220 488 .. 219 491 .. 0.86 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 1.1e-11 Ion_trans 165 npdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnf 235 + +g++ F ++ ++l +l+++ltt + +d++ ++ ++ +++i+f++f ++g +++lnll a+i + f FUN_001624-T1 35 VECEGNYYFLKLEDSLRSLLVLLTTANNPDVMMYAYMKN--RLYAIFFIIFTMIGLYFFLNLLTAIIYNQF 103 45567778888999999*************999888888..8**************************999 PP == domain 2 score: 98.5 bits; conditional E-value: 3.6e-32 Ion_trans 2 kifelfilllillntvvlal..etyfqpeekel.klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil......... 85 k+f++f+ +++ +n+vv+ + e+ + + + +++ i++++f+ ++le l+k++alg+ ++Y +s+ ni+ vv+l +++ i FUN_001624-T1 220 KVFDYFSDFVVAVNVVVISVllEYEQDTLWENPkSIIGIANFFFVLYYALEQLIKLWALGC-QRYRSSMVNIYAGVVTLALVLAEISyvslygfpf 314 6899999999999999888843333333333336***************************.****************999995555577888887 PP Ion_trans 86 ...ses.....keslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkk.............e. 159 s + ++ +l +++ +l +rllr++ ++ l+ ++++l++ lk+l ++ +++ v ++fa++g+ lf++ + + FUN_001624-T1 315 sndS-QeklseNSLRNLTQIINILITFRLLRIVPNVRALSLILETLLKLLKNLRPFAGIIVAVYYVFAVLGMMLFANVT-DpsdvgkqetrllnKk 408 6651.145653378888899999999999999999999*************************************4444.3699999999998735 PP Ion_trans 160 ekewenpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqelte 240 + ++ ++ +nFd+f+ al+ l ++ ++w l + s+++ +yfv +++++ +l++nl++a+i+++f ++ e FUN_001624-T1 409 CGTFGQLQYYANNFDDFFAALVVLWDLMVVNNWHVFLKEYSLVF-SWWSQLYFVAWYLISVILVINLFVALILEAFVSQWE 488 8889999999*********************************9.*******************************98755 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.5 3.3 0.0011 14 194 222 .. 75 103 .. 46 105 .. 0.85 2 ! 7.1 0.5 0.00035 4.4 8 58 .. 251 302 .. 244 310 .. 0.78 3 ! 12.9 0.1 6.1e-06 0.078 92 160 .. 323 391 .. 313 395 .. 0.93 4 ! 10.7 7.0 2.9e-05 0.37 160 223 .. 418 484 .. 411 486 .. 0.83 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0011 PKD_channel 194 LGpllllalvflvifillnlflaiindsy 222 L ++++++ ++ + +lnl+ aii++++ FUN_001624-T1 75 LYAIFFIIFTMIGLYFFLNLLTAIIYNQF 103 446899********************998 PP == domain 2 score: 7.1 bits; conditional E-value: 0.00035 PKD_channel 8 lflllievvfvvfvlyfvveeilkirker.asylrsvwnlldlaivvlsvvl 58 ++ +i ++ +fvly++ e ++k++ + ++y +s+ n+ ++ + v++ FUN_001624-T1 251 NPKSIIGIANFFFVLYYALEQLIKLWALGcQRYRSSMVNIYAGVVTLALVLA 302 555667788899*****************99999999998777666665555 PP == domain 3 score: 12.9 bits; conditional E-value: 6.1e-06 PKD_channel 92 ldqllriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtq 160 ++++lr+++ ++ +l t +ll+++ ++ +sl+ +tl + lk+l fa +iv + ++a+lg++lf + FUN_001624-T1 323 SENSLRNLTQIINILITFRLLRIVPNVRALSLILETLLKLLKNLRPFAGIIVAVYYVFAVLGMMLFANV 391 6788999999999*****************************************************986 PP == domain 4 score: 10.7 bits; conditional E-value: 2.9e-05 PKD_channel 160 qasnfsnlvksiltlfrlilgdfqyt...elesgnrvLGpllllalvflvifillnlflaiindsye 223 +a+nf ++ + ++l l++ + e + + + l+++a ++++++++nlf+a+i ++++ FUN_001624-T1 418 YANNFDDFFAALVVLWDLMVVNNWHVflkEYSLVFSWWSQLYFVAWYLISVILVINLFVALILEAFV 484 6789999999999998888877544455555557788999************************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (563 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1349 (0.0528088); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 5584.71 // Query: FUN_001624-T2 [L=777] Description: FUN_001624 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-54 183.5 43.1 9.5e-28 97.5 21.7 2.1 2 Ion_trans Ion transport protein 8.7e-05 22.5 47.7 0.12 12.2 0.1 6.4 6 PKD_channel Polycystin cation channel Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.0 13.4 3.5e-30 4.5e-26 2 235 .. 63 317 .. 62 321 .. 0.91 2 ! 97.5 21.7 7.4e-32 9.5e-28 2 240 .. 434 702 .. 433 705 .. 0.86 Alignments for each domain: == domain 1 score: 92.0 bits; conditional E-value: 3.5e-30 Ion_trans 2 kifelfilllillntvvlaletyfqp.............eekel..klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslis 82 k f + + l+i+ln+++ +e + + + e++++vf+ f+ ++++k lg k++l+s w + ++ +++ + + FUN_001624-T2 63 KPFRWGFSLVIFLNLMLAFVEKPSSFtstsdprfrgkrpD---PpcGVTECVEIVFLLCFVCDLFMKSQFLGR-KTFLKSRWLLTYCILLTICFCD 154 67899999************99999988888888775444...355***************************.********************** PP Ion_trans 83 lilseskeslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkk..............e.ekew 163 +++s s ++ +r+ r+lr++ l++ + ++ l+++++r+++++l++l+llll l +fa++g+ +f +k + + + e FUN_001624-T2 155 VLVSIS---AGCKERIRIRRVLRPFFLLQNSSLMKKLLHAIKRTVPEILSVLFLLLLHLWFFAMCGMLMFPQKATMrrnktvadiecspeQmRAEI 247 *98444...899999*******************************************************5555557899*****99987256666 PP Ion_trans 164 enpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnf 235 + + +g++ F ++ ++l +l+++ltt + +d++ ++ ++ +++i+f++f ++g +++lnll a+i + f FUN_001624-T2 248 GVECEGNYYFLKLEDSLRSLLVLLTTANNPDVMMYAYMKN--RLYAIFFIIFTMIGLYFFLNLLTAIIYNQF 317 777799999**********************999988888..8**************************999 PP == domain 2 score: 97.5 bits; conditional E-value: 7.4e-32 Ion_trans 2 kifelfilllillntvvlal..etyfqpeekel.klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil......... 85 k+f++f+ +++ +n+vv+ + e+ + + + +++ i++++f+ ++le l+k++alg+ ++Y +s+ ni+ vv+l +++ i FUN_001624-T2 434 KVFDYFSDFVVAVNVVVISVllEYEQDTLWENPkSIIGIANFFFVLYYALEQLIKLWALGC-QRYRSSMVNIYAGVVTLALVLAEISyvslygfpf 528 6899999999999999888843333333333336***************************.****************999995555577888887 PP Ion_trans 86 ...ses.....keslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkk.............e. 159 s + ++ +l +++ +l +rllr++ ++ l+ ++++l++ lk+l ++ +++ v ++fa++g+ lf++ + + FUN_001624-T2 529 sndS-QeklseNSLRNLTQIINILITFRLLRIVPNVRALSLILETLLKLLKNLRPFAGIIVAVYYVFAVLGMMLFANVT-DpsdvgkqetrllnKk 622 6651.145653378888899999999999999999999*************************************4444.3699999999998735 PP Ion_trans 160 ekewenpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnfqelte 240 + ++ ++ +nFd+f+ al+ l ++ ++w l + s+++ +yfv +++++ +l++nl++a+i+++f ++ e FUN_001624-T2 623 CGTFGQLQYYANNFDDFFAALVVLWDLMVVNNWHVFLKEYSLVF-SWWSQLYFVAWYLISVILVINLFVALILEAFVSQWE 702 8889999999*********************************9.*******************************98755 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.7 2.6 0.0039 49 14 63 .. 109 159 .. 104 165 .. 0.84 2 ! 9.1 0.6 8.7e-05 1.1 109 162 .. 173 226 .. 169 234 .. 0.90 3 ! 4.6 3.7 0.0021 27 194 222 .. 289 317 .. 257 319 .. 0.85 4 ! 6.6 0.5 0.00052 6.7 8 58 .. 465 516 .. 458 524 .. 0.78 5 ! 12.2 0.1 9.5e-06 0.12 92 160 .. 537 605 .. 527 609 .. 0.93 6 ! 10.1 7.0 4.4e-05 0.56 160 223 .. 632 698 .. 625 700 .. 0.83 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.0039 PKD_channel 14 evvfvvfvlyfvveeilkirker.asylrsvwnlldlaivvlsvvlivlai 63 e v +vf+l fv ++++k + + + l+s w l ++++ ++ ++++i FUN_001624-T2 109 ECVEIVFLLCFVCDLFMKSQFLGrKTFLKSRWLLTYCILLTICFCDVLVSI 159 667789**************999788999***8888888888887776665 PP == domain 2 score: 9.1 bits; conditional E-value: 8.7e-05 PKD_channel 109 lkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtqas 162 l+ + +l+ ++ m+ l ++++r +++++++ +++++ + +a+ g+l+f ++a FUN_001624-T2 173 LRPFFLLQNSSLMKKLLHAIKRTVPEILSVLFLLLLHLWFFAMCGMLMFPQKAT 226 666778889999*************************************99875 PP == domain 3 score: 4.6 bits; conditional E-value: 0.0021 PKD_channel 194 LGpllllalvflvifillnlflaiindsy 222 L ++++++ ++ + +lnl+ aii++++ FUN_001624-T2 289 LYAIFFIIFTMIGLYFFLNLLTAIIYNQF 317 446899********************998 PP == domain 4 score: 6.6 bits; conditional E-value: 0.00052 PKD_channel 8 lflllievvfvvfvlyfvveeilkirker.asylrsvwnlldlaivvlsvvl 58 ++ +i ++ +fvly++ e ++k++ + ++y +s+ n+ ++ + v++ FUN_001624-T2 465 NPKSIIGIANFFFVLYYALEQLIKLWALGcQRYRSSMVNIYAGVVTLALVLA 516 555667788899*****************99999999998777666665555 PP == domain 5 score: 12.2 bits; conditional E-value: 9.5e-06 PKD_channel 92 ldqllriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtq 160 ++++lr+++ ++ +l t +ll+++ ++ +sl+ +tl + lk+l fa +iv + ++a+lg++lf + FUN_001624-T2 537 SENSLRNLTQIINILITFRLLRIVPNVRALSLILETLLKLLKNLRPFAGIIVAVYYVFAVLGMMLFANV 605 6788999999999*****************************************************986 PP == domain 6 score: 10.1 bits; conditional E-value: 4.4e-05 PKD_channel 160 qasnfsnlvksiltlfrlilgdfqyt...elesgnrvLGpllllalvflvifillnlflaiindsye 223 +a+nf ++ + ++l l++ + e + + + l+++a ++++++++nlf+a+i ++++ FUN_001624-T2 632 YANNFDDFFAALVVLWDLMVVNNWHVflkEYSLVFSWWSQLYFVAWYLISVILVINLFVALILEAFV 698 6789999999999998888877544455555557788999************************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (777 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1470 (0.0575455); expected 510.9 (0.02) Passed bias filter: 634 (0.0248189); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7308.28 // Query: FUN_001624-T3 [L=668] Description: FUN_001624 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-45 154.4 32.8 3.3e-26 92.4 13.4 2.1 2 Ion_trans Ion transport protein 0.00015 21.7 31.6 0.086 12.7 0.1 5.6 5 PKD_channel Polycystin cation channel Domain annotation for each model (and alignments): >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.4 13.4 2.6e-30 3.3e-26 2 235 .. 63 317 .. 62 321 .. 0.91 2 ! 67.9 11.4 8e-23 1e-18 2 193 .. 434 656 .. 433 664 .. 0.84 Alignments for each domain: == domain 1 score: 92.4 bits; conditional E-value: 2.6e-30 Ion_trans 2 kifelfilllillntvvlaletyfqp.............eekel..klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslis 82 k f + + l+i+ln+++ +e + + + e++++vf+ f+ ++++k lg k++l+s w + ++ +++ + + FUN_001624-T3 63 KPFRWGFSLVIFLNLMLAFVEKPSSFtstsdprfrgkrpD---PpcGVTECVEIVFLLCFVCDLFMKSQFLGR-KTFLKSRWLLTYCILLTICFCD 154 67899999************99999988888888775444...355***************************.********************** PP Ion_trans 83 lilseskeslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkk..............e.ekew 163 +++s s ++ +r+ r+lr++ l++ + ++ l+++++r+++++l++l+llll l +fa++g+ +f +k + + + e FUN_001624-T3 155 VLVSIS---AGCKERIRIRRVLRPFFLLQNSSLMKKLLHAIKRTVPEILSVLFLLLLHLWFFAMCGMLMFPQKATMrrnktvadiecspeQmRAEI 247 *98444...899999*******************************************************5555557899*****99987256666 PP Ion_trans 164 enpdngrtnFdnfgnallwlfqtlttegwgdilyatldekgsaiaviyfvlfiilggvlllnlliaviidnf 235 + + +g++ F ++ ++l +l+++ltt + +d++ ++ ++ +++i+f++f ++g +++lnll a+i + f FUN_001624-T3 248 GVECEGNYYFLKLEDSLRSLLVLLTTANNPDVMMYAYMKN--RLYAIFFIIFTMIGLYFFLNLLTAIIYNQF 317 777799999**********************999988888..8**************************999 PP == domain 2 score: 67.9 bits; conditional E-value: 8e-23 Ion_trans 2 kifelfilllillntvvlal..etyfqpeekel.klleildlvftviftlemllkiialglkkkYlrspwnilDfvvvlpslislil......... 85 k+f++f+ +++ +n+vv+ + e+ + + + +++ i++++f+ ++le l+k++alg+ ++Y +s+ ni+ vv+l +++ i FUN_001624-T3 434 KVFDYFSDFVVAVNVVVISVllEYEQDTLWENPkSIIGIANFFFVLYYALEQLIKLWALGC-QRYRSSMVNIYAGVVTLALVLAEISyvslygfpf 528 6899999999999999888843333333333336***************************.****************999995555577888887 PP Ion_trans 86 ...ses.....keslsllrvlrllrllrllrlirrleglrtlvnslirslksllnlllllllvlfifaiigvqlfggklkk.............e. 159 s + ++ +l +++ +l +rllr++ ++ l+ ++++l++ lk+l ++ +++ v ++fa++g+ lf++ + + FUN_001624-T3 529 sndS-QeklseNSLRNLTQIINILITFRLLRIVPNVRALSLILETLLKLLKNLRPFAGIIVAVYYVFAVLGMMLFANVT-DpsdvgkqetrllnKk 622 6651.145653378888899999999999999999999*************************************4444.3699999999998735 PP Ion_trans 160 ekewenpdngrtnFdnfgnallwlfqtlttegwg 193 + ++ ++ +nFd+f+ al+ l ++ ++w FUN_001624-T3 623 CGTFGQLQYYANNFDDFFAALVVLWDLMVVNNWH 656 8889999999********************9996 PP >> PKD_channel Polycystin cation channel # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.0 2.6 0.0032 41 14 63 .. 109 159 .. 104 165 .. 0.84 2 ! 9.4 0.6 7.2e-05 0.92 109 162 .. 173 226 .. 169 234 .. 0.90 3 ! 4.8 3.7 0.0017 22 194 222 .. 289 317 .. 257 319 .. 0.85 4 ! 6.8 0.5 0.00043 5.5 8 58 .. 465 516 .. 458 524 .. 0.78 5 ! 12.7 0.1 6.8e-06 0.086 92 160 .. 537 605 .. 527 620 .. 0.93 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.0032 PKD_channel 14 evvfvvfvlyfvveeilkirker.asylrsvwnlldlaivvlsvvlivlai 63 e v +vf+l fv ++++k + + + l+s w l ++++ ++ ++++i FUN_001624-T3 109 ECVEIVFLLCFVCDLFMKSQFLGrKTFLKSRWLLTYCILLTICFCDVLVSI 159 667789**************999788999***8888888888887776665 PP == domain 2 score: 9.4 bits; conditional E-value: 7.2e-05 PKD_channel 109 lkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtqas 162 l+ + +l+ ++ m+ l ++++r +++++++ +++++ + +a+ g+l+f ++a FUN_001624-T3 173 LRPFFLLQNSSLMKKLLHAIKRTVPEILSVLFLLLLHLWFFAMCGMLMFPQKAT 226 666778889999*************************************99875 PP == domain 3 score: 4.8 bits; conditional E-value: 0.0017 PKD_channel 194 LGpllllalvflvifillnlflaiindsy 222 L ++++++ ++ + +lnl+ aii++++ FUN_001624-T3 289 LYAIFFIIFTMIGLYFFLNLLTAIIYNQF 317 446899********************998 PP == domain 4 score: 6.8 bits; conditional E-value: 0.00043 PKD_channel 8 lflllievvfvvfvlyfvveeilkirker.asylrsvwnlldlaivvlsvvl 58 ++ +i ++ +fvly++ e ++k++ + ++y +s+ n+ ++ + v++ FUN_001624-T3 465 NPKSIIGIANFFFVLYYALEQLIKLWALGcQRYRSSMVNIYAGVVTLALVLA 516 555667788899*****************99999999998777666665555 PP == domain 5 score: 12.7 bits; conditional E-value: 6.8e-06 PKD_channel 92 ldqllriilavlvflttlkllkvlrfnktmslltktlaralkdlagfalvivilflayaqlgvllfGtq 160 ++++lr+++ ++ +l t +ll+++ ++ +sl+ +tl + lk+l fa +iv + ++a+lg++lf + FUN_001624-T3 537 SENSLRNLTQIINILITFRLLRIVPNVRALSLILETLLKLLKNLRPFAGIIVAVYYVFAVLGMMLFANV 605 6788999999999*****************************************************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (668 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1444 (0.0565277); expected 510.9 (0.02) Passed bias filter: 712 (0.0278724); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6372.19 // Query: FUN_001625-T1 [L=178] Description: FUN_001625 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.004 17.4 0.0 0.0082 16.4 0.0 1.6 1 rve_3 Integrase core domain Domain annotation for each model (and alignments): >> rve_3 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 3.2e-07 0.0082 1 29 [. 127 155 .. 127 169 .. 0.89 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 3.2e-07 rve_3 1 lgikisyiepgkPqqNglvEsfngtlrde 29 +g+k+ +i+p++ Ng +E+f +t+++ FUN_001625-T1 127 NGVKQTLIAPYHLPSNGQAERFVQTFKQF 155 589***********************985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 638 (0.0249755); expected 510.9 (0.02) Passed bias filter: 474 (0.0185555); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1760.53 // Query: FUN_001626-T1 [L=278] Description: FUN_001626 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.9e-15 55.2 10.8 7.9e-15 55.2 10.8 2.3 2 bZIP_1 bZIP transcription factor 3.1e-09 37.2 9.0 3.1e-09 37.2 9.0 2.6 3 bZIP_2 Basic region leucine zipper 2.7e-05 25.1 9.1 2.7e-05 25.1 9.1 2.4 2 bZIP_Maf bZIP Maf transcription factor 0.00066 20.5 0.7 0.00066 20.5 0.7 2.3 2 TPR Nucleoprotein TPR-like domain 0.0031 18.2 2.9 0.0031 18.2 2.9 1.9 1 ANG-1 ANG-1-like domain 0.0094 16.3 5.2 0.015 15.7 4.3 1.5 1 Spc29 Spindle Pole Component 29 ------ inclusion threshold ------ 0.083 12.6 4.6 0.11 12.2 4.6 1.4 1 DUF4407 Domain of unknown function (DUF4407) 0.09 13.7 0.2 0.3 12.0 0.2 1.8 1 FlaC_arch Flagella accessory protein C (FlaC) 0.11 12.9 12.4 0.026 14.9 8.4 1.9 2 DUF724 Protein of unknown function (DUF724) 0.17 13.0 3.5 0.29 12.3 1.1 2.3 2 DUF4404 Domain of unknown function (DUF4404) 0.18 12.7 1.6 0.39 11.6 1.7 1.6 1 Tll0287-like Tll0287 0.24 10.3 9.3 0.33 9.9 9.3 1.1 1 Orbi_VP5 Orbivirus outer capsid protein VP5 0.98 10.4 4.2 0.95 10.5 2.3 2.1 2 DUF7310 Coiled-coil region of unknown function (DUF73 2.4 9.2 5.0 2.1 9.4 1.0 2.8 3 Arg_decarbox_C Arginine decarboxylase C-terminal helical ext 3.5 8.5 15.8 1 10.3 12.8 1.5 2 Fez1 Fez1 9.2 7.2 10.3 1.9 9.4 3.4 2.6 3 Csm1_N Csm1 N-terminal domain Domain annotation for each model (and alignments): >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 6.4 1e+04 46 59 .. 46 59 .. 34 61 .. 0.51 2 ! 55.2 10.8 5e-18 7.9e-15 1 63 [. 143 205 .. 143 206 .. 0.97 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 6.4 bZIP_1 46 kseleelkkevekL 59 + l+k+++ FUN_001626-T1 46 CKISTLLNKNCSDI 59 33333455666555 PP == domain 2 score: 55.2 bits; conditional E-value: 5e-18 bZIP_1 1 ekelKrekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekLkskv 63 e++lKr +rk+kN+ +A++sR++K++++e Le+rv+a ++eN+ L++++++l+ +v L++++ FUN_001626-T1 143 ERALKRIRRKIKNKLSAQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRALLTEL 205 799******************************************************999876 PP >> bZIP_2 Basic region leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.1 3.6 5.8e+03 19 28 .. 34 43 .. 32 55 .. 0.61 2 ! 37.2 9.0 2e-12 3.1e-09 5 53 .. 147 196 .. 143 197 .. 0.96 3 ? -3.1 0.3 7.5 1.2e+04 9 11 .. 246 248 .. 239 260 .. 0.54 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 3.6 bZIP_2 19 sRekkkqkee 28 sR+ ++q+++ FUN_001626-T1 34 SRKDRRQDMN 43 5555555554 PP == domain 2 score: 37.2 bits; conditional E-value: 2e-12 bZIP_2 5 yrerRr.kNneAAkrsRekkkqkeeeleervkeLekeNarLrqkveqlek 53 +r rR+ kN +A+ sR kkk++ e le+rv+ + eN+ L+qkv++le+ FUN_001626-T1 147 KRIRRKiKNKLSAQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLET 196 789*********************************************96 PP == domain 3 score: -3.1 bits; conditional E-value: 7.5 bZIP_2 9 Rrk 11 R++ FUN_001626-T1 246 RER 248 222 PP >> bZIP_Maf bZIP Maf transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 9.1 1.7e-08 2.7e-05 21 90 .. 138 207 .. 136 209 .. 0.90 2 ? -1.5 2.1 3.4 5.4e+03 52 68 .. 240 256 .. 203 272 .. 0.57 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.7e-08 bZIP_Maf 21 lteeeverLKqrRRrlKNrgyakscrkrrlqqkeelekekekleeelerlkqelsrlrqekdalkrkneq 90 lt+ e LK++RR+ KN++ a+++r+++ + e+lek e + e++ l+q+++ l+ al+ + ++ FUN_001626-T1 138 LTKAEERALKRIRRKIKNKLSAQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRALLTELNR 207 68889999**********************************************9998877777766655 PP == domain 2 score: -1.5 bits; conditional E-value: 3.4 bZIP_Maf 52 qkeelekekekleeele 68 +ke le+e++ ++e+++ FUN_001626-T1 240 KKEALERERNLTAERQK 256 23444444444444443 PP >> TPR Nucleoprotein TPR-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 2 3.3e+03 26 58 .. 38 70 .. 20 87 .. 0.54 2 ! 20.5 0.7 4.1e-07 0.00066 4 49 .. 172 217 .. 169 235 .. 0.81 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2 TPR 26 LsrQVqvLlkeveelrgglgslereeleelarg 58 + L+k + l+++++ ++ e+l ++ FUN_001626-T1 38 RRQDMNLLCKISTLLNKNCSDIKSYPDEDLFDN 70 455555555555556666654333333333322 PP == domain 2 score: 20.5 bits; conditional E-value: 4.1e-07 TPR 4 elkaklerlerenerlqqqlrDLsrQVqvLlkeveelrgglgsler 49 l++++e +++en++lqq+++ L++ V+ Ll e+++lr+ ++e+ FUN_001626-T1 172 GLEKRVEACNSENSILQQKVDSLETTVRALLTELNRLRKVALEKES 217 5899**********************************98764332 PP >> ANG-1 ANG-1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 2.9 2e-06 0.0031 45 101 .. 143 203 .. 137 207 .. 0.74 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 2e-06 ANG-1 45 qeeLeslree.keqL..qellsrqselieeLeksLeaassnsslLqrqqaqLlesvq.llv 101 ++ L+ +r++ k++L qe ++++e +e Lek++ea +s++s+Lq++ ++L+ +v+ ll+ FUN_001626-T1 143 ERALKRIRRKiKNKLsaQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRaLLT 203 455666654434455225566677899*****************************74555 PP >> Spc29 Spindle Pole Component 29 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 4.3 9.1e-06 0.015 102 165 .. 138 201 .. 130 236 .. 0.81 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 9.1e-06 Spc29 102 lapsdesrldriyddvkkivrlekklddqkleIkeLkreleqqrtvnseLqeklarleeevkrl 165 l+ ++e l+ri++++k+ + ++k+ ++ L++ +e + ns Lq+k++ le +v+ l FUN_001626-T1 138 LTKAEERALKRIRRKIKNKLSAQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRAL 201 46688899**********999****************************************544 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 4.6 6.9e-05 0.11 107 206 .. 151 257 .. 103 278 .] 0.64 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 6.9e-05 DUF4407 107 keIdqeldeekn.eeadaakaqlaqa...lraelaelqaqiaalqaeidaaekeldelqkearcelegtk.......gtgttgvpGkGpeakekee 191 I+ +l+++ + ++++++ + l++ ++e + lq+++++l+++++a+ +el++l+k a ++ + ++ g G ++ k+e FUN_001626-T1 151 RKIKNKLSAQESrRKKKEYVEGLEKRveaCNSENSILQQKVDSLETTVRALLTELNRLRKVALEKESRKRtlkaksiG----TQTGTCLKCHLKKE 242 455555554443033444545544446667777777788888888888888888888887777666665555543221....12344444444555 PP DUF4407 192 eldaaqaelaalqak 206 +l++ ++ a+ q++ FUN_001626-T1 243 ALERERNLTAERQKA 257 555555444443332 PP >> FlaC_arch Flagella accessory protein C (FlaC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.2 0.00019 0.3 9 41 .. 170 202 .. 167 203 .. 0.93 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00019 FlaC_arch 9 lekleseletlrkeneeisksveeieenvkkll 41 +e le ++e+ +en+ ++++v+++e +v+ ll FUN_001626-T1 170 VEGLEKRVEACNSENSILQQKVDSLETTVRALL 202 678999*************************98 PP >> DUF724 Protein of unknown function (DUF724) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.1 0.97 1.6e+03 151 177 .. 72 100 .. 8 125 .. 0.54 2 ? 14.9 8.4 1.6e-05 0.026 88 166 .. 147 225 .. 145 251 .. 0.88 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.97 DUF724 151 ekkeakdkeiarlks..eaekleqeiedv 177 e +a+d ei+ +s +a+ e++++d+ FUN_001626-T1 72 EATDASDTEISGEQSflHASGCEEKMDDM 100 44555555555443322444444444444 PP == domain 2 score: 14.9 bits; conditional E-value: 1.6e-05 DUF724 88 kapqsrlnkLlslkdkqtklleelkklekkiaeeesekrkleeeidelekkilelerqeallkekkeakdkeiarlkse 166 k +++++++ ls ++++ k++e ++lek+++ ++se++ l++++d le +++ l +++ l++ +k+++ +lk++ FUN_001626-T1 147 KRIRRKIKNKLSAQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRALLTELNRLRKVALEKESRKRTLKAK 225 678999*****************************************************99997776666666666654 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 1.1 0.00018 0.29 16 63 .. 136 183 .. 132 196 .. 0.85 2 ? 0.3 0.2 1 1.6e+03 14 41 .. 190 217 .. 181 231 .. 0.63 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00018 DUF4404 16 esldeetrakLeelaedieellaeedaaaeekelvdrlneaverFeee 63 +l ++++ L+ ++++i+++l+ ++++ ++ke v++l++ ve e FUN_001626-T1 136 IPLTKAEERALKRIRRKIKNKLSAQESRRKKKEYVEGLEKRVEACNSE 183 678899999**********************99999999999876665 PP == domain 2 score: 0.3 bits; conditional E-value: 1 DUF4404 14 edesldeetrakLeelaedieellaeed 41 + +sl+++ ra L+el++ + +l++e+ FUN_001626-T1 190 KVDSLETTVRALLTELNRLRKVALEKES 217 3466667777777777665555555444 PP >> Tll0287-like Tll0287 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.7 0.00024 0.39 67 115 .. 188 245 .. 131 262 .. 0.62 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00024 Tll0287-like 67 rneadefEaealerflk.........nlegkkyfryarpirvkeesClkCHgtpedap 115 +++ d++E+ + + +++ ++e +k a+ i +++ +ClkCH ++e+ FUN_001626-T1 188 QQKVDSLETTVRALLTElnrlrkvalEKESRKRTLKAKSIGTQTGTCLKCHLKKEALE 245 3444666655544442222233454555588999999999999********9997655 PP >> Orbi_VP5 Orbivirus outer capsid protein VP5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 9.3 0.00021 0.33 99 184 .. 139 227 .. 134 255 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00021 Orbi_VP5 99 eekeeevaekynkeieeklg..eelkkvrkvvkkeakaeeeeeeqiealekalkalekivkeeeekleklak.ALkkEeeeRtedekkl 184 ++ ee++ ++ +++i++kl+ e+ +k +++v++ +k+ e+ +++ +l++ +++le+ v+ ++l++l+k AL+kE+++Rt + k + FUN_001626-T1 139 TKAEERALKRIRRKIKNKLSaqESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRALLTELNRLRKvALEKESRKRTLKAKSI 227 577899999999****99984455678899****************************************876**********987776 PP >> DUF7310 Coiled-coil region of unknown function (DUF7310) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 6.3 1e+04 42 51 .. 93 102 .. 67 105 .. 0.58 2 ? 10.5 2.3 0.00059 0.95 25 74 .. 170 219 .. 140 226 .. 0.79 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 6.3 DUF7310 42 leerlaeLea 51 ee++++++a FUN_001626-T1 93 CEEKMDDMDA 102 4555666555 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00059 DUF7310 25 aaalaerlealeerldeleerlaeLeaavqAlrGyvGsvravneeVErra 74 + l++r+ea +++ + l++++++Le++v Al ++ +r+v e E r FUN_001626-T1 170 VEGLEKRVEACNSENSILQQKVDSLETTVRALLTELNRLRKVALEKESRK 219 45578888888888889999************999999999988877775 PP >> Arg_decarbox_C Arginine decarboxylase C-terminal helical extension # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 1.6 2.6e+03 28 39 .. 116 127 .. 106 128 .. 0.81 2 ? 9.4 1.0 0.0013 2.1 16 46 .. 146 174 .. 142 176 .. 0.92 3 ? -2.2 0.1 5.5 8.7e+03 23 37 .. 244 258 .. 240 266 .. 0.75 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.6 Arg_decarbox_C 28 rLsaeerkalle 39 +Ls+ee++++++ FUN_001626-T1 116 KLSDEEKETFVS 127 89******9986 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0013 Arg_decarbox_C 16 lerlrrqveaagrLsaeerkalleeleagLk 46 l+r+rr++++ +Lsa+e ++ +e+ +gL+ FUN_001626-T1 146 LKRIRRKIKN--KLSAQESRRKKKEYVEGLE 174 6899******..7*****************8 PP == domain 3 score: -2.2 bits; conditional E-value: 5.5 Arg_decarbox_C 23 veaagrLsaeerkal 37 +e+ +L+ae +ka+ FUN_001626-T1 244 LERERNLTAERQKAF 258 555568999988887 PP >> Fez1 Fez1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 4.4 7e+03 101 101 .. 61 61 .. 14 126 .. 0.56 2 ? 10.3 12.8 0.00064 1 45 160 .. 147 259 .. 135 270 .. 0.67 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 4.4 Fez1 101 e 101 + FUN_001626-T1 61 S 61 2 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00064 Fez1 45 akleekeeqikeleeslesktlelevceneLqrkkneaellrekvgkleeevselreelaelsaeekelalesdeakaqrqeaeealeslkrever 140 +++++k ++ +++es ++k+ +e +e++++ ++e+++l++kv +le+ v+ l +el++l++ + e + ++++ ka+ +++ + lk FUN_001626-T1 147 KRIRRKIKNKLSAQESRRKKKEYVEGLEKRVEACNSENSILQQKVDSLETTVRALLTELNRLRKVALEKESRKRTLKAKSIG-TQTGTCLKC--HL 239 34555666667889999999999**********************************9999777666655555555554443.222222222..22 PP Fez1 141 lkaeLkeerqrkeeqaksFe 160 k+ L+ er+ + e++k+F FUN_001626-T1 240 KKEALERERNLTAERQKAFR 259 33444455554444444444 PP >> Csm1_N Csm1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.6 0.7 1.1e+03 44 68 .. 144 168 .. 135 173 .. 0.72 2 ? 0.8 0.6 0.57 9e+02 29 53 .. 155 180 .. 149 182 .. 0.63 3 ? 9.4 3.4 0.0012 1.9 27 66 .. 182 221 .. 173 225 .. 0.87 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.7 Csm1_N 44 esLkeqlaeleekvkeleerrkkqe 68 +Lk+ ++++k++ +e+rrkk+e FUN_001626-T1 144 RALKRIRRKIKNKLSAQESRRKKKE 168 5666666777888888888777764 PP == domain 2 score: 0.8 bits; conditional E-value: 0.57 Csm1_N 29 NsvLsqkletkdqe.iesLkeqlael 53 N + +q+ + k++e +e L++++++ FUN_001626-T1 155 NKLSAQESRRKKKEyVEGLEKRVEAC 180 45555555544444378888888765 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0012 Csm1_N 27 hENsvLsqkletkdqeiesLkeqlaeleekvkeleerrkk 66 ENs+L+qk+++ ++ + +L +l+ l++ e e+r+++ FUN_001626-T1 182 SENSILQQKVDSLETTVRALLTELNRLRKVALEKESRKRT 221 6**************************9988888877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (278 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2068 (0.0809552); expected 510.9 (0.02) Passed bias filter: 798 (0.031239); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2710.40 // Query: FUN_001627-T1 [L=110] Description: FUN_001627 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 395 (0.0154629); expected 510.9 (0.02) Passed bias filter: 336 (0.0131533); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.40s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1117.05 // Query: FUN_001628-T1 [L=281] Description: FUN_001628 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-38 131.1 1.2 4.6e-38 130.3 0.6 1.7 2 Cyclin_N Cyclin, N-terminal domain 2.6e-18 66.7 0.3 1.7e-17 64.0 0.0 2.2 3 Cyclin_C Cyclin, C-terminal domain ------ inclusion threshold ------ 0.035 14.7 0.0 0.069 13.7 0.0 1.4 1 HA1 Hemagglutinin I 0.23 12.4 0.0 0.48 11.3 0.0 1.6 1 Cyclin_C_2 Cyclin C-terminal domain Domain annotation for each model (and alignments): >> Cyclin_N Cyclin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.3 0.6 7.2e-42 4.6e-38 2 127 .] 26 152 .. 25 152 .. 0.98 2 ? -2.0 0.0 0.59 3.7e+03 27 42 .. 219 234 .. 204 257 .. 0.61 Alignments for each domain: == domain 1 score: 130.3 bits; conditional E-value: 7.2e-42 Cyclin_N 2 ilkylrekeekslpkkdyl.dqqpeltekmRailidwlvevhekfklspetlylavnyldRflskksvpkkklqlvgvtcLllAaKyeeisppkve 96 +l++l ++ee ++p+ y+ q+e++++mR+++ +w++ev+e+ +++e++ l+vnyldRfls ++k++lql+g++c++lA+K++++sp + e FUN_001628-T1 26 VLENLLTTEESYIPNCGYFsIVQEEIEPRMRRMVTTWMLEVCEEQMCEEEVFPLSVNYLDRFLSIVPTRKNQLQLLGAVCMFLASKLKQTSPLSAE 121 7899***************9999************************************************************************* PP Cyclin_N 97 dlvyitdnaytkeeilemErliLetLkfdls 127 +l+++tdn++t +e++++E l+L +Lk+dls FUN_001628-T1 122 KLCIYTDNSITCQELVDWEILVLGKLKWDLS 152 *****************************96 PP == domain 2 score: -2.0 bits; conditional E-value: 0.59 Cyclin_N 27 tekmRailidwlvevh 42 ++ +R+ l+++l ++ FUN_001628-T1 219 QTWTRTELVSFLQGLT 234 4466777777765543 PP >> Cyclin_C Cyclin, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.2 1.3e+03 1 28 [. 78 106 .. 78 122 .. 0.56 2 ? -1.2 0.0 0.42 2.7e+03 47 72 .. 101 127 .. 91 134 .. 0.71 3 ! 64.0 0.0 2.7e-21 1.7e-17 1 91 [. 154 257 .. 154 273 .. 0.85 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.2 Cyclin_C 1 ptplsFlrrflka.adaskdleletlaky 28 p+++++l rfl + +++l+l+ + + FUN_001628-T1 78 PLSVNYLDRFLSIvPTRKNQLQLLGAVCM 106 56778888886662222223444433333 PP == domain 2 score: -1.2 bits; conditional E-value: 0.42 Cyclin_C 47 iAaaavylarktl.nspewtetlehyt 72 + a +++la+k sp e+l yt FUN_001628-T1 101 LGAVCMFLASKLKqTSPLSAEKLCIYT 127 568899999999844444555555554 PP == domain 3 score: 64.0 bits; conditional E-value: 2.7e-21 Cyclin_C 1 ptplsFlrrf.lkaadaskdleletlakylleltlldydflkyppSliAaaavylarktl....nspewt.....etlehytgyseedlkecvkll 86 +tp++Fl+ + + + + d ++++a ++++l+ +d +fl+y pS+iAaa+v++a + l ++++wt + l+ +t+++ e l++c+ l+ FUN_001628-T1 154 VTPYDFLQQIfCRLSLPNVD-VIRKHAATFIALCCTDEKFLMYAPSTIAAASVCAAFNGLtaneQNQTWTrtelvSFLQGLTKVEPEYLRSCQDLM 248 7*******998999777779.9**************************************998777779955555669999999************ PP Cyclin_C 87 lell....s 91 +e+l + FUN_001628-T1 249 EEVLqinvN 257 ***964332 PP >> HA1 Hemagglutinin I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 1.1e-05 0.069 26 56 .. 36 66 .. 29 75 .. 0.87 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.1e-05 HA1 26 rfiqvdgyhsiviqeagdrvrrtsttwavvv 56 +i gy siv +e r+rr ttw + v FUN_001628-T1 36 SYIPNCGYFSIVQEEIEPRMRRMVTTWMLEV 66 577888*********************9876 PP >> Cyclin_C_2 Cyclin C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 7.6e-05 0.48 21 69 .. 169 222 .. 148 253 .. 0.74 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7.6e-05 Cyclin_C_2 21 ekrieklykkareilksalltDayflYtPsqialaallladekla.....eryl 69 +++ ++k+a ++ + ++Y+Ps ia a++ a ++l+ +++ FUN_001628-T1 169 LPNVDVIRKHAATFIALCCTDEKFLMYAPSTIAAASVCAAFNGLTaneqnQTWT 222 3578899999*999996666666789***********99998888555544554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (281 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 655 (0.025641); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 2834.00 // Query: FUN_001629-T1 [L=127] Description: FUN_001629 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.4 0.2 0.14 12.2 0.2 1.0 1 REase-ARP Restriction Endonuclease associating with ARP Domain annotation for each model (and alignments): >> REase-ARP Restriction Endonuclease associating with ARP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.2 5.5e-06 0.14 29 113 .. 26 112 .. 7 124 .. 0.73 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 5.5e-06 REase-ARP 29 dllprnillpnvlkeireelerylkendeislhkl...fhhllSSqalcfNlfcpliadpdllalllqsdlfpeevdelkfEykprke 113 +++ ++i + ++ ++ r+ ++++ + + +++l + +h+l q+l N fc+++++ +++l ++ l e+ + +f+++p+++ FUN_001629-T1 26 RMKFAEITEYEECENTRHIMQSSDRVGGSFHLTDSlgqINHCLNIQILTCNNFCYFMVYFFVTRLTFE-LLRMEKTEQSTFDFTPKNT 112 445556666666666666666666666688888745779*******************9888888888.88899**********9444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (127 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1067 (0.0417694); expected 510.9 (0.02) Passed bias filter: 547 (0.0214132); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1299.04 // Query: FUN_001630-T1 [L=524] Description: FUN_001630 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-15 54.7 0.1 2.3e-14 53.4 0.1 1.6 1 HLH Helix-loop-helix DNA-binding domain 6.4e-09 36.4 0.2 6.4e-09 36.4 0.2 2.0 2 Hairy_orange Hairy Orange ------ inclusion threshold ------ 0.02 15.4 0.4 0.071 13.6 0.4 1.9 1 bHLH_SAC51 Transcription factor SAC51 bHLH domain 0.061 14.3 0.0 0.25 12.4 0.0 2.1 1 bHLH_NCOA Nuclear receptor coactivators bHLH domain 0.11 13.2 0.3 0.21 12.3 0.3 1.4 1 Ig_PVRIG Transmembrane protein PVRIG, immunoglobulin-lik 0.5 11.0 4.5 11 6.7 0.3 2.7 2 DUF4023 Protein of unknown function (DUF4023) Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.4 0.1 5.4e-18 2.3e-14 4 53 .] 85 139 .. 84 139 .. 0.90 Alignments for each domain: == domain 1 score: 53.4 bits; conditional E-value: 5.4e-18 HLH 4 ahnerERrRrdriNdafdeLrellP.....tlppdkKlsKaeiLrlAieYIkqLq 53 +h +E+rRrdriN ++ eL +llP ++ + Kl+KaeiL+l++eY+k+L+ FUN_001630-T1 85 SHKVIEKRRRDRINTSLGELSQLLPaqtssGKQGSGKLEKAEILELTVEYLKSLK 139 699**********************87766555666****************995 PP >> Hairy_orange Hairy Orange # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.4 0.2 1.5e-12 6.4e-09 5 39 .. 175 211 .. 174 212 .. 0.96 2 ? -2.4 0.2 2 8.5e+03 28 36 .. 268 276 .. 267 278 .. 0.85 Alignments for each domain: == domain 1 score: 36.4 bits; conditional E-value: 1.5e-12 Hairy_orange 5 GFreCakEVsryLstvegvds.dlr.srLlsHLqrcl 39 G+ +C +EV r+L++ve +d+ + + +rL++HL + + FUN_001630-T1 175 GYKDCTEEVFRFLVNVEAMDMqQPCfQRLMAHLRHQI 211 9********************************9975 PP == domain 2 score: -2.4 bits; conditional E-value: 2 Hairy_orange 28 rsrLlsHLq 36 r+rL HL+ FUN_001630-T1 268 RARLHGHLG 276 68******8 PP >> bHLH_SAC51 Transcription factor SAC51 bHLH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.4 1.7e-05 0.071 10 57 .. 90 145 .. 86 151 .. 0.80 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.7e-05 bHLH_SAC51 10 eqskkdKiktalkiLesvVP........GakgkealllLDEAidYLKlLKqkLgss 57 e+ ++d+i t l+ L ++ P G+ + e + +L+ ++YLK+LK +L+ FUN_001630-T1 90 EKRRRDRINTSLGELSQLLPaqtssgkqGSGKLEKAEILELTVEYLKSLKSHLNEQ 145 77899************99966665333334458899*************999865 PP >> bHLH_NCOA Nuclear receptor coactivators bHLH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 5.8e-05 0.25 32 79 .. 86 133 .. 70 135 .. 0.90 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 5.8e-05 bHLH_NCOA 32 krstekrrreqenkyieelaelisanlsdidnlnvkPdkcailketvk 79 ++ ekrrr++ n + el++l+ a s + + k +k +il tv+ FUN_001630-T1 86 HKVIEKRRRDRINTSLGELSQLLPAQTSSGKQGSGKLEKAEILELTVE 133 5567***************************************99997 PP >> Ig_PVRIG Transmembrane protein PVRIG, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.3 5e-05 0.21 16 94 .. 235 314 .. 220 321 .. 0.75 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 5e-05 Ig_PVRIG 16 sftvrCgflGsgsislvtvslegldgag..gtkLavLhPelGvqqwapasqarWetktsvsltltleesearsslanttfC 94 ++ + +f+G+ s s t s++g+ +a+ ++k a Lh +lG + +p++ ++ +t+++ s + ++r +++++++C FUN_001630-T1 235 RMASKRNFQGTTSSSSSTSSSTGKGSANggKIKRARLHGHLGGSNATPSQSSNGNTTSNSS-DNENGSDNTRETQSDSAIC 314 45566789**********9999887775115778**************9999988887766.4455556677777888777 PP >> DUF4023 Protein of unknown function (DUF4023) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.4 0.008 34 10 24 .. 141 155 .. 131 160 .. 0.86 2 ? 6.7 0.3 0.0025 11 21 36 .. 344 359 .. 339 360 .. 0.88 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.008 DUF4023 10 klhdkQaKdeknrkr 24 l+++Q+Kd+k ++ FUN_001630-T1 141 HLNEQQEKDLKKAQT 155 599*******98775 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0025 DUF4023 21 nrkrqGtGhPaKKlPn 36 +r ++ +GhP + lP+ FUN_001630-T1 344 SRGGHSNGHPTHPLPS 359 6889***********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (524 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1527 (0.0597769); expected 510.9 (0.02) Passed bias filter: 749 (0.0293208); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.32u 0.45s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 5117.04 // Query: FUN_001631-T1 [L=568] Description: FUN_001631 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-43 147.3 0.2 1.2e-42 145.8 0.0 1.8 2 RhoGAP RhoGAP domain 5.8e-27 95.2 1.1 5.8e-27 95.2 1.1 1.9 2 CRAL_TRIO_2 Divergent CRAL/TRIO domain 2.4e-08 34.4 0.5 7.1e-08 32.9 0.2 2.0 2 CRAL_TRIO CRAL/TRIO domain ------ inclusion threshold ------ 2.8 6.9 5.9 3.6 6.5 5.9 1.1 1 UNC80 Protein UNC80 central region Domain annotation for each model (and alignments): >> RhoGAP RhoGAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.67 4.3e+03 95 115 .. 270 290 .. 260 316 .. 0.53 2 ! 145.8 0.0 1.8e-46 1.2e-42 1 147 [. 392 538 .. 392 539 .. 0.97 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.67 RhoGAP 95 alkellekLPkanretLryLl 115 ++ +l+++L + r+ +++L+ FUN_001631-T1 270 RVIQLYHELDRKYRKNIKALF 290 455555555555555555554 PP == domain 2 score: 145.8 bits; conditional E-value: 1.8e-46 RhoGAP 1 PlivekcveylekrgletegifRvsgsksevkelkealdkgeevdldleeedvhdvaslLKlflrelpepLltkelyeefleaakledeeerleal 96 P ++ v++l+++gle+egifR s+++++vk+ ++ +d g+ v + dvh +a ++K+flrelpepL+t++ly+ +++ +++d+ e+++ + FUN_001631-T1 392 PVVMSTSVKFLREYGLEVEGIFRRSANTKTVKDFCSMFDAGHFVT-YKNPDDVHCAAVIIKKFLRELPEPLMTFNLYDIIIASTSIPDSAEKIKVV 486 7889999********************************999997.88999********************************************* PP RhoGAP 97 kellek.LPkanretLryLlehLkrvaknseknkMtaenLaivfaPtllrsp 147 +l++ LP++n+ +L++L+e+L++v ++s++nkMt+ nLaivf+P+l++s+ FUN_001631-T1 487 WYILRNeLPDENFLLLKFLMEFLSEVMSHSSENKMTSMNLAIVFGPNLMWSK 538 ****999*******************************************97 PP >> CRAL_TRIO_2 Divergent CRAL/TRIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.2 1.1 9.1e-31 5.8e-27 1 135 [. 213 345 .. 213 347 .. 0.96 2 ? -1.1 0.0 0.48 3.1e+03 20 72 .. 447 496 .. 428 544 .. 0.61 Alignments for each domain: == domain 1 score: 95.2 bits; conditional E-value: 9.1e-31 CRAL_TRIO_2 1 grpVlvfiskll.kaslddlerllfyllktlseklkgkpfvvvvdhtgvtsenfpslsllkklydllprklkknlkavyvvhpstflktvlktlgs 95 gr+V+vf ++++ + ++ d+ rl+ +ll+tl ++++++++++v++h g+ts+n+ps+s + +ly+ l+rk++kn+ka+++vhps +k++ +tl + FUN_001631-T1 213 GRSVIVFSACRMpPIDTIDHSRLFSFLLHTL-DQYVENDYSIVYFHFGLTSKNKPSISRVIQLYHELDRKYRKNIKALFIVHPSNTIKLLWATLAK 307 89******9999899999*************.***********************************************************99999 PP CRAL_TRIO_2 96 llgskklkkkvhyvssleelaegidkeelpkelp.gvlsyd 135 ++ s+k+ +k+ y+ l+ l e++ +++ ++p v ++d FUN_001631-T1 308 IF-SPKFSRKLYYITHLSALGEHVHLDQI--DIPpQVKEHD 345 99.66688*********************..***9999998 PP == domain 2 score: -1.1 bits; conditional E-value: 0.48 CRAL_TRIO_2 20 erllfyllktlseklkgkp.fvvvvdhtgvtsenfpslsllkklydllprklkk 72 +++ +l +l e+l++ + +++ +t++ s++ +k + ++l+++l++ FUN_001631-T1 447 AVIIKKFLRELPEPLMTFNlYDIIIASTSI----PDSAEKIKVVWYILRNELPD 496 455555555555666666667777766662....23455555555555555554 PP >> CRAL_TRIO CRAL/TRIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.9 0.2 1.1e-11 7.1e-08 3 147 .. 201 335 .. 199 337 .. 0.85 2 ? -3.1 0.0 1.3 8.6e+03 65 91 .. 431 456 .. 413 467 .. 0.48 Alignments for each domain: == domain 1 score: 32.9 bits; conditional E-value: 1.1e-11 CRAL_TRIO 3 sgkvylhgrDkegrpvlylrlgridpk.ksseeelvrllvlvleralkeleegqvegltviiDlkglslskmdkkplsllkkiikilqdnyperlg 97 + + + g Dk gr v+++ + r+ p + ++++l+ +l+++l++ + e ++ +v + + +s ++ + ++s + ++ + l + y ++ FUN_001631-T1 201 HNILSVAGDDKSGRSVIVFSACRMPPIdTIDHSRLFSFLLHTLDQYV-EN-----DYSIVYFHFGLTS-KNKP--SISRVIQLYHELDRKYRKNIK 287 5677899****************999865556799999999999877.33.....4455555554444.4444..4******************** PP CRAL_TRIO 98 kilivnaPkifnviwklikpfldpktreKikflknsneeeLekyidpeql 147 +++iv+++ ++ +w ++ ++ +pk+ +K+ ++ + + L ++++ +q+ FUN_001631-T1 288 ALFIVHPSNTIKLLWATLAKIFSPKFSRKLYYI--THLSALGEHVHLDQI 335 *********************************..66788*****99998 PP == domain 2 score: -3.1 bits; conditional E-value: 1.3 CRAL_TRIO 65 lkglslskmdkkplsllkkiikilqdn 91 ++ +k + +++ ++ iik + + FUN_001631-T1 431 AGHFVTYKNP-DDVHCAAVIIKKFLRE 456 4443333333.1233333333333333 PP >> UNC80 Protein UNC80 central region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 5.9 0.00056 3.6 243 366 .. 56 183 .. 1 203 [. 0.56 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.00056 UNC80 243 isfalvlde...edskdslkssshtlksdtaveekktkeeskgkkllrklrrggsrllsikgnrsfklkkdgslssikragslksrklsrqdsese 335 + f + e ++ d l+ss++t+++d+av+e + + ++k+ + + k+rrg+ + ++r +lkk+g +s+ a s+ + +s FUN_001631-T1 56 MDFDNLNLEqdfLQEFDPLSSSTTTTSVDNAVDEDRLTFHRKDSAESMKVRRGSKV--IVGREREAHLKKNGTQSAADEATSSDVLETGGSSHQSS 149 344433323013457899******************99999999999999998765..56789999****99999888887776555544444444 PP UNC80 336 neellls...sqeedtvtdieseelsaeepsiep 366 ++ + + ++ d e+ s++ ++ FUN_001631-T1 150 GDKGDSDgmgELGKEASADSAVESNSKNCNGASN 183 4443332111333444444444444444333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (568 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 692 (0.0270894); expected 510.9 (0.02) Passed bias filter: 504 (0.0197299); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.43s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 5480.92 // Query: FUN_001632-T1 [L=142] Description: FUN_001632 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-09 37.5 1.3 4.3e-09 36.8 1.3 1.3 1 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding ------ inclusion threshold ------ 0.018 15.7 2.5 0.028 15.1 2.5 1.3 1 C2H2-zf_KIN17 KIN17 C2H2-type zinc finger domain 0.048 14.4 0.5 0.078 13.7 0.4 1.4 1 zf-C2H2_2 C2H2 type zinc-finger (2 copies) 0.064 14.5 0.3 0.18 13.1 0.3 1.8 1 zf-C2H2_4 C2H2-type zinc finger 0.11 13.1 0.9 0.26 11.9 0.9 1.6 1 Zf-C2H2_ZNF451_6th Sixth Zinc fingers C2H2 type, ZNF451 Domain annotation for each model (and alignments): >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.8 1.3 8.4e-13 4.3e-09 1 27 [] 57 83 .. 57 83 .. 0.98 Alignments for each domain: == domain 1 score: 36.8 bits; conditional E-value: 8.4e-13 zf-C2H2_jaz 1 qfYCvlCdKyFksenalqnHlkSKkHK 27 q+YC+ C++yF +++a+q+H++S+ H+ FUN_001632-T1 57 QHYCIQCARYFVDDKAFQEHVRSRVHR 83 8*************************7 PP >> C2H2-zf_KIN17 KIN17 C2H2-type zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 2.5 5.5e-06 0.028 3 29 .. 58 84 .. 57 85 .. 0.93 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 5.5e-06 C2H2-zf_KIN17 3 wYCqvCeKqcrDenGFkcHcaSEsHvR 29 YC C + + D+ +F+ H++S H + FUN_001632-T1 58 HYCIQCARYFVDDKAFQEHVRSRVHRK 84 6**********************9987 PP >> zf-C2H2_2 C2H2 type zinc-finger (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.4 1.5e-05 0.078 50 78 .. 57 85 .. 42 98 .. 0.88 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.5e-05 zf-C2H2_2 50 kleClvCekefkslealreHmkdkgHcki 78 ++ C+ C + f + +a++eH++++ H k FUN_001632-T1 57 QHYCIQCARYFVDDKAFQEHVRSRVHRKR 85 689***********************985 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.3 3.5e-05 0.18 1 22 [. 58 79 .. 58 81 .. 0.93 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3.5e-05 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlkk 22 ++C +C + F++ ka++ H+++ FUN_001632-T1 58 HYCIQCARYFVDDKAFQEHVRS 79 68******************97 PP >> Zf-C2H2_ZNF451_6th Sixth Zinc fingers C2H2 type, ZNF451 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.9 5e-05 0.26 3 20 .. 59 76 .. 58 79 .. 0.94 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 5e-05 Zf-C2H2_ZNF451_6th 3 YCpnCNqvFVDEtstqsH 20 YC C + FVD+ q H FUN_001632-T1 59 YCIQCARYFVDDKAFQEH 76 ************999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 902 (0.0353102); expected 510.9 (0.02) Passed bias filter: 636 (0.0248972); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.35s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1468.98 // Query: FUN_001633-T1 [L=309] Description: FUN_001633 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1410 (0.0551967); expected 510.9 (0.02) Passed bias filter: 605 (0.0236837); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.43s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3042.08 // Query: FUN_001634-T1 [L=287] Description: FUN_001634 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (287 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1252 (0.0490115); expected 510.9 (0.02) Passed bias filter: 472 (0.0184772); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2860.28 // Query: FUN_001635-T1 [L=195] Description: FUN_001635 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.007 16.6 0.0 0.012 15.9 0.0 1.4 1 DUF5399 Family of unknown function (DUF5399) Domain annotation for each model (and alignments): >> DUF5399 Family of unknown function (DUF5399) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.7e-07 0.012 61 99 .. 41 77 .. 35 112 .. 0.80 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.7e-07 DUF5399 61 lktpWAyFfpPkrfrkqrrspfafrvvPSLGseekqded 99 + W yF+pP ++r + ++ + f+ SLG +ek++ FUN_001635-T1 41 NSQSWGYFSPPFHYRALPIQLYKFK--HSLGNLEKDTCA 77 5799******************775..7*****998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (195 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 618 (0.0241926); expected 510.9 (0.02) Passed bias filter: 407 (0.0159327); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1996.32 // Query: FUN_001636-T1 [L=221] Description: FUN_001636 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 590 (0.0230965); expected 510.9 (0.02) Passed bias filter: 372 (0.0145625); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2174.85 // Query: FUN_001637-T1 [L=115] Description: FUN_001637 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.79 10.6 6.9 1 10.2 6.9 1.2 1 MamF_MmsF Magnetosome magnetite crystal formation protein fa Domain annotation for each model (and alignments): >> MamF_MmsF Magnetosome magnetite crystal formation protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 6.9 4.1e-05 1 18 85 .. 2 70 .. 1 78 [. 0.63 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 4.1e-05 MamF_MmsF 18 ipllgiigPliiwllkkdkspfvrehakealnfqitllilllvalllflilg...liglllllllgilwlv 85 +p++gii l wl+ +k+ f+ + + + +q+ + ++l++ l++ i + + ++++l+ + +++ FUN_001637-T1 2 TPVIGII-SLAPWLIVHEKEGFLLDVTAAFVAWQLYWQATILITSLIC-ITSsveSLCFVFFLFSFHFAFY 70 6899998.7877999999999**************6664444444444.4423442333333333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 848 (0.0331963); expected 510.9 (0.02) Passed bias filter: 370 (0.0144842); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1169.18 // Query: FUN_001638-T1 [L=389] Description: FUN_001638 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-88 297.5 20.5 3e-88 297.1 20.5 1.2 1 WD40_RLD RCC1-like domain 6.6e-78 257.6 35.7 8.5e-12 46.0 0.1 7.1 7 RCC1 Regulator of chromosome condensation (RCC1) repeat 5.7e-51 169.6 46.1 7.9e-11 41.9 1.2 8.2 8 RCC1_2 Regulator of chromosome condensation (RCC1) repeat 2.2e-10 40.7 9.6 0.0026 17.4 0.0 4.3 4 Alsin_RLD Alsin RCC1-like domain Domain annotation for each model (and alignments): >> WD40_RLD RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 297.1 20.5 4.6e-92 3e-88 1 363 [] 13 385 .. 11 385 .. 0.84 Alignments for each domain: == domain 1 score: 297.1 bits; conditional E-value: 4.6e-92 WD40_RLD 1 evlvwGsgdagqLGlgd..ekkrPrlvkll...sglevvqvaaGgmhtlaltedGkvyswGvndegaLGrdteeeeesestPkevegeveelegkv 91 ++l+wG++++gqL lg+ ++ +P+ ++l+ ++ ++ +++ Gg ht+++ e+ +++++G+n++g+LG ++ + P + + v FUN_001638-T1 13 QLLSWGANSYGQLCLGHkeDVLVPESCELNdlpENSKISSISGGGGHTAVIIESQDLFMCGWNNKGQLGLGDID-----DRPLLCQV---PFLALV 100 589**********996633666688555543326688999*****************************99966.....34632222...23344* PP WD40_RLD 92 vqvaaGdshslaltedGevyawGrnseGqlGlgeekk.qktPvkvveklekekvkkiaaGanhslaltedgevytwGsgeqgqLgk.kserrresk 185 +qv++G++h+la+te G +y+wG+ns+GqlG+g+ ++P+++ e+ +k++ ++iaaG +hs++ dg+v+++G++++gqLg k ++++ + FUN_001638-T1 101 KQVSCGWNHTLAITEAG-LYVWGSNSFGQLGIGKIGGcITRPTLC-ESFAKQQAVSIAAGLRHSAVALGDGSVWCCGANKKGQLGLgKPGNSQATL 194 **************888.**************998865999*877.8899999999*****************************32333344444 PP WD40_RLD 186 lealvpkkvgkvvdiaaGsyhsfaltedgkvyawGlNnygqlGl.......gstenrv....sPtkveeslkg..vkqiagGehhslaltedgevy 268 +++ p gkv ++aaGs+ ++alt+ g v++wG+N++gq+G +++ P+ ++ +g v+++++G++h la+ted++v+ FUN_001638-T1 195 KQVVFPGFHGKVIQVAAGSHLTAALTDMGGVFCWGSNQHGQCGEppegtntEEK---ApifaLPQLIQGLISGshVTKLKSGWSHLLAVTEDQRVF 287 44455555488*********************************9997543333...24569999995545556799999**************** PP WD40_RLD 269 awGrndygqlGlgeeee....esePtkvpglegvkvvqiaaGsehslavtedgkvyswGfgesgqlGlgdeeedvvePtlve.lk.kkvvsvsaGg 358 +wGr+dygqlGlge++ ++Pt+v+++eg+k+ ia+G+eh++++ g+v++wG++e+g +G+g e +v++P v+ l+ +v +++Gg FUN_001638-T1 288 TWGRADYGQLGLGENVVkqgyCRNPTEVTDVEGAKQ--IACGAEHNMVLMGGGSVVTWGWNEHGICGTGYE-INVHTPGVVSqLEgSRVSVIGCGG 380 *************77664455666***********9..*******************************54.46999*****87678********* PP WD40_RLD 359 qhsla 363 h++a FUN_001638-T1 381 GHCFA 385 **986 PP >> RCC1 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.5 0.1 5.8e-13 3.7e-09 3 50 .] 13 63 .. 11 63 .. 0.93 2 ! 44.2 0.1 4.8e-15 3.1e-11 4 50 .] 69 113 .. 67 113 .. 0.95 3 ! 36.2 0.1 1.5e-12 9.7e-09 3 49 .. 117 164 .. 115 165 .. 0.89 4 ! 37.5 1.0 5.6e-13 3.6e-09 1 50 [] 168 219 .. 168 219 .. 0.92 5 ! 37.2 0.4 7.3e-13 4.7e-09 2 50 .] 223 280 .. 222 280 .. 0.85 6 ! 46.0 0.1 1.3e-15 8.5e-12 3 50 .] 285 334 .. 283 334 .. 0.87 7 ! 38.4 5.5 2.9e-13 1.9e-09 2 50 .] 338 386 .. 337 386 .. 0.97 Alignments for each domain: == domain 1 score: 37.5 bits; conditional E-value: 5.8e-13 RCC1 3 rvytWGrneyGqLGlgteesklvP..qkveslsgn.kvvqvacGadhtval 50 ++ +WG n+yGqL lg++e++lvP + ++ l++n k+ +++ G+ ht+++ FUN_001638-T1 13 QLLSWGANSYGQLCLGHKEDVLVPesCELNDLPENsKISSISGGGGHTAVI 63 689*********************888889999999************986 PP == domain 2 score: 44.2 bits; conditional E-value: 4.8e-15 RCC1 4 vytWGrneyGqLGlgteesklvP..qkveslsgnkvvqvacGadhtval 50 ++ +G+n++GqLGlg+ +++ P ++v++l v+qv+cG++ht+a+ FUN_001638-T1 69 LFMCGWNNKGQLGLGDIDDR--PllCQVPFLA--LVKQVSCGWNHTLAI 113 8*******************..8889*****9..9************97 PP == domain 3 score: 36.2 bits; conditional E-value: 1.5e-12 RCC1 3 rvytWGrneyGqLGlgte...esklvPqkveslsgnkvvqvacGadhtva 49 +y WG+n++GqLG g+ P++ es+ ++ +v++a+G +h+++ FUN_001638-T1 117 GLYVWGSNSFGQLGIGKIggcI--TRPTLCESFAKQQAVSIAAGLRHSAV 164 59*************9996334..55**********************96 PP == domain 4 score: 37.5 bits; conditional E-value: 5.6e-13 RCC1 1 dGrvytWGrneyGqLGlgte.esklvPqkveslsgn.kvvqvacGadhtval 50 dG+v+++G n++GqLGlg+ +s+ + ++v ++ + kv+qva+G++ t+al FUN_001638-T1 168 DGSVWCCGANKKGQLGLGKPgNSQATLKQVVFPGFHgKVIQVAAGSHLTAAL 219 8****************99987777779999998889*************97 PP == domain 5 score: 37.2 bits; conditional E-value: 7.3e-13 RCC1 2 GrvytWGrneyGqLGlgte....esk.....lvPqkveslsgn.kvvqvacGadhtval 50 G v++WG+n++Gq+G ++e e + +Pq++++l + +v++ +G++h +a+ FUN_001638-T1 223 GGVFCWGSNQHGQCGEPPEgtntE-EkapifALPQLIQGLISGsHVTKLKSGWSHLLAV 280 99**************77753232.25777777*******9999***********9996 PP == domain 6 score: 46.0 bits; conditional E-value: 1.3e-15 RCC1 3 rvytWGrneyGqLGlgte.esk....lvPqkveslsgnkvvqvacGadhtval 50 rv+tWGr +yGqLGlg + + k + P+ v+ + ++q+acGa+h ++l FUN_001638-T1 285 RVFTWGRADYGQLGLGENvV-KqgycRNPTEVTDVE--GAKQIACGAEHNMVL 334 8*****************63.3355577********..9***********997 PP == domain 7 score: 38.4 bits; conditional E-value: 2.9e-13 RCC1 2 GrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 G+v tWG+ne+G +G+g e ++++P v+ l+g +v + cG+ h++al FUN_001638-T1 338 GSVVTWGWNEHGICGTGYEINVHTPGVVSQLEGSRVSVIGCGGGHCFAL 386 8899*******************************************97 PP >> RCC1_2 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.1 0.0002 1.2 20 30 .] 14 24 .. 11 24 .. 0.92 2 ! 19.6 0.8 1.3e-07 0.00082 1 30 [] 50 79 .. 50 79 .. 0.98 3 ! 41.9 1.2 1.2e-14 7.9e-11 1 30 [] 100 128 .. 100 128 .. 0.99 4 ! 32.9 1.1 8.3e-12 5.3e-08 2 30 .] 153 181 .. 152 181 .. 0.98 5 ! 32.6 1.4 1.1e-11 6.8e-08 1 30 [] 206 235 .. 206 235 .. 0.99 6 ! 29.3 0.0 1.1e-10 7.3e-07 1 30 [] 267 296 .. 267 296 .. 0.97 7 ! 31.1 0.6 3.2e-11 2.1e-07 2 29 .. 322 349 .. 321 350 .. 0.97 8 ? 1.3 1.5 0.072 4.6e+02 4 14 .. 376 386 .. 373 386 .. 0.87 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0002 RCC1_2 20 vycwGdNsyGQ 30 +++wG NsyGQ FUN_001638-T1 14 LLSWGANSYGQ 24 89********9 PP == domain 2 score: 19.6 bits; conditional E-value: 1.3e-07 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 ++s++ G+ H+ ++ ++ +++ +G+N++GQ FUN_001638-T1 50 ISSISGGGGHTAVIIESQDLFMCGWNNKGQ 79 789**************************9 PP == domain 3 score: 41.9 bits; conditional E-value: 1.2e-14 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 v++v++G+nH+la+t+ G +y+wG+Ns+GQ FUN_001638-T1 100 VKQVSCGWNHTLAITEAG-LYVWGSNSFGQ 128 89****************.**********9 PP == domain 4 score: 32.9 bits; conditional E-value: 8.3e-12 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 vs+aaG +Hs + + dG v+c+G N +GQ FUN_001638-T1 153 VSIAAGLRHSAVALGDGSVWCCGANKKGQ 181 89**************************9 PP == domain 5 score: 32.6 bits; conditional E-value: 1.1e-11 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 v++vaaG+ + aLt+ G v+cwG+N++GQ FUN_001638-T1 206 VIQVAAGSHLTAALTDMGGVFCWGSNQHGQ 235 89***************************9 PP == domain 6 score: 29.3 bits; conditional E-value: 1.1e-10 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 v+++ +G++H la+t+d rv++wG+ +yGQ FUN_001638-T1 267 VTKLKSGWSHLLAVTEDQRVFTWGRADYGQ 296 78999************************9 PP == domain 7 score: 31.1 bits; conditional E-value: 3.2e-11 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyG 29 +++a+G+ H +L+ G v +wG+N++G FUN_001638-T1 322 KQIACGAEHNMVLMGGGSVVTWGWNEHG 349 89*************************9 PP == domain 8 score: 1.3 bits; conditional E-value: 0.072 RCC1_2 4 vaaGdnHslaL 14 + +G+ H++aL FUN_001638-T1 376 IGCGGGHCFAL 386 89******998 PP >> Alsin_RLD Alsin RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 4e-07 0.0026 252 317 .. 68 130 .. 59 146 .. 0.87 2 ! 8.1 0.1 0.00027 1.7 286 317 .. 152 183 .. 144 193 .. 0.90 3 ? 3.0 0.1 0.01 64 286 318 .. 206 238 .. 192 250 .. 0.90 4 ! 14.9 0.4 2.4e-06 0.015 250 323 .. 283 358 .. 257 379 .. 0.78 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 4e-07 Alsin_RLD 252 qlftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlg 317 lf G +nkG lG Gd r + ++ l v +++G +ht++ t G ly wG n+ qlg FUN_001638-T1 68 DLFMCGWNNKGQLGLGDIDDRPLLCQVPFLALV--KQVSCGWNHTLAITEAG-LYVWGSNSFGQLG 130 59**************************99875..67889*******99766.***********99 PP == domain 2 score: 8.1 bits; conditional E-value: 0.00027 Alsin_RLD 286 vcsiaaGkehtvvrtldGrlyhwGlndkeqlg 317 siaaG +h+ v dG ++ G n+k qlg FUN_001638-T1 152 AVSIAAGLRHSAVALGDGSVWCCGANKKGQLG 183 579***************************98 PP == domain 3 score: 3.0 bits; conditional E-value: 0.01 Alsin_RLD 286 vcsiaaGkehtvvrtldGrlyhwGlndkeqlgn 318 v +aaG + t + t G ++ wG n++ q g+ FUN_001638-T1 206 VIQVAAGSHLTAALTDMGGVFCWGSNQHGQCGE 238 7789**************************985 PP == domain 4 score: 14.9 bits; conditional E-value: 2.4e-06 Alsin_RLD 250 ntqlftlGasnkGllGtGdhikrasvar..lekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlgnieels 323 + ++ft G ++ G lG G+ + ++ r e d G ia+G eh +v G + wG n++ g+ +e+ FUN_001638-T1 283 DQRVFTWGRADYGQLGLGENVVKQGYCRnpTEVTDVEGAKQIACGAEHNMVLMGGGSVVTWGWNEHGICGTGYEIN 358 4579**************9987666555223555666999**************************9998877775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (389 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 461 (0.0180466); expected 510.9 (0.02) Passed bias filter: 370 (0.0144842); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3954.59 // Query: FUN_001639-T1 [L=569] Description: FUN_001639 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-43 147.3 0.8 6.9e-43 146.3 0.8 1.5 1 Fuz_longin_1 First Longin domain of FUZ, MON1 and HPS1 6e-34 116.7 0.3 6e-34 116.7 0.3 1.8 2 Fuz_longin_2 Second Longin domain of FUZ, MON1 and HPS1 1.2e-28 100.3 0.2 5.9e-28 98.0 0.0 2.2 2 Fuz_longin_3 Third Longin domain of FUZ, MON1 and HPS1 Domain annotation for each model (and alignments): >> Fuz_longin_1 First Longin domain of FUZ, MON1 and HPS1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 146.3 0.8 8.1e-47 6.9e-43 1 125 [] 170 292 .. 170 292 .. 0.99 Alignments for each domain: == domain 1 score: 146.3 bits; conditional E-value: 8.1e-47 Fuz_longin_1 1 khllvlssaGkpiytrygdesesllfslfgvlqavisfmqdqkdeltsisaentkvVflekeplllvavsrsgesesqLrrqLevvytqilsvlgl 96 kh++v+s+aGkpiy+ryg+ e++l++l+gv+qa++sf+q k++++++ a+++k+Vfl ++ ++lvav+r++es++qL qL++vy+qilsvl++ FUN_001639-T1 170 KHVFVFSEAGKPIYSRYGN--EEKLATLMGVMQALVSFVQVGKNTIRCVLAGSHKFVFLVRGHVILVAVARTQESVTQLGLQLSYVYNQILSVLTY 263 8******************..*************************************************************************** PP Fuz_longin_1 97 aqltklferrenedlrkllsgledlldkL 125 +ql ++ e+r+n+dlr+llsg+e+++d+L FUN_001639-T1 264 SQLARIMEQRRNYDLRRLLSGTEKFIDNL 292 ***************************98 PP >> Fuz_longin_2 Second Longin domain of FUZ, MON1 and HPS1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 1 8.8e+03 7 21 .. 215 230 .. 210 235 .. 0.79 2 ! 116.7 0.3 7.1e-38 6e-34 1 97 [. 330 428 .. 330 429 .. 0.97 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1 Fuz_longin_2 7 lllv.snklvalvrsk 21 ++l+ s+k+v lvr++ FUN_001639-T1 215 CVLAgSHKFVFLVRGH 230 5566589999999986 PP == domain 2 score: 116.7 bits; conditional E-value: 7.1e-38 Fuz_longin_2 1 ksllfalllvsnklvalvrskkasLhpsDllllfllvessssfksaeswipiclpkfnp.gvlhalvsfll.gqnlvllllsgdkpaffelselke 94 k+l+fa+l+++n+l++lvr+k++sLhp+Dl+l+f+lv++s+sf++aesw+piclp f++ g+l+a++s+l+ +++++lllls+d++aff l e k+ FUN_001639-T1 330 KDLVFAILVANNQLITLVRPKNYSLHPADLHLIFNLVNASTSFQTAESWTPICLPRFDNsGYLYAHISYLAdDCPACLLLLSTDRNAFFALAETKQ 425 689*******************************************************************999**********************9 PP Fuz_longin_2 95 rfv 97 +++ FUN_001639-T1 426 KTL 428 976 PP >> Fuz_longin_3 Third Longin domain of FUZ, MON1 and HPS1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 0.48 4.1e+03 24 66 .. 185 235 .. 168 271 .. 0.66 2 ! 98.0 0.0 6.9e-32 5.9e-28 2 102 .] 459 558 .. 458 558 .. 0.99 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.48 Fuz_longin_3 24 pytseerrrrLrafYkslhstlhske........rklkllykvseseklla 66 y +ee+ +L+ + + l+s ++ + + k ++ v+ ++ l+a FUN_001639-T1 185 RYGNEEKLATLMGVMQALVSFVQVGKntircvlaGSHKFVFLVRGHVILVA 235 455566666666666666666665555555555555666666666555555 PP == domain 2 score: 98.0 bits; conditional E-value: 6.9e-32 Fuz_longin_3 2 llhFLyksrssvqflapsleskpytseerrrrLrafYkslhstlhskerklkllykvsesekllawitetfeLyvlfsplvpkaalissankllkw 97 l hF+yks+s+ q+++p++e +py ++e+++rL +Y +lh+++hs +r+lk+l +v+++e ll+w+t+ feLy+ fsplv+k +i+++nkll+w FUN_001639-T1 459 LYHFIYKSKSTAQYTSPEIE-APYVDKEEQDRLFGLYLYLHHRIHSGSRPLKILCHVGTREMLLGWVTSGFELYAAFSPLVTKPDAINAINKLLRW 553 78******************.*************************************************************************** PP Fuz_longin_3 98 ikkee 102 ik+ee FUN_001639-T1 554 IKREE 558 **997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (569 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 750 (0.02936); expected 510.9 (0.02) Passed bias filter: 594 (0.0232531); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5420.74 // Query: FUN_001640-T1 [L=371] Description: FUN_001640 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-42 145.0 21.8 5e-42 144.7 21.8 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.75 10.6 5.0 9 7.1 1.2 2.8 2 DUF3382 Domain of unknown function (DUF3382) 2.3 8.5 4.6 5 7.5 0.4 2.8 2 TMIE TMIE protein Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 144.7 21.8 5.9e-46 5e-42 1 260 [] 49 306 .. 49 306 .. 0.89 Alignments for each domain: == domain 1 score: 144.7 bits; conditional E-value: 5.9e-46 xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrtptnifllnLavaDllvlllvlpfalvyallegdwvf....gevlCklvtaldvvnltasillltaisiDRYlaIvkp 90 gN lVi+++ n klrt+ n+f++++a Dll++l ++p ++ l +++w + g +lCkl++++ +++++ il+l +i++DR+l++++p FUN_001640-T1 49 GNSLVITAFKLntNGKLRTVNNMFIVSMAAGDLLLTLGSMPERITRVLSNDRWLIegnlGIFLCKLANFVEKLCMIVAILHLSMIAVDRFLVVFYP 144 8*******99844667*************************************9877779999********************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 91 lkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakk 186 ++ i+tk++al +i+++W+l++l++ p +++ + k++ k++ +C +w+v+y+++l+vlg l ++++ +y+ i+ ++r++++ FUN_001640-T1 145 YRK--IVTKKKALWFIVIAWLLSALFCGPLFYYANLKKK---KGQISCKTRSFF--PNWKVWYLIFLIVLGTTL--VFVVSLYISIAIHVRRNKRP 231 999..9***************************998877...99****987655..33*************997..77777899999999999888 PP xxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 187 eks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + +k++r ++++lk++l++v++f +c+lPy + ++ ++ ++ + +++t l i+++l+y+ns++NPiiY FUN_001640-T1 232 GCCmsvEGMKNVRLRSRILKMVLAIVLAFYCCFLPYWTGWIFCVY--SSIEVICDDTYLFISIFLIYANSAINPIIY 306 7542224444455555********************998888888..777889999999****************** PP >> DUF3382 Domain of unknown function (DUF3382) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.0093 79 13 59 .. 40 87 .. 36 107 .. 0.83 2 ? 7.1 1.2 0.0011 9 24 94 .. 177 258 .. 152 261 .. 0.61 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.0093 DUF3382 13 alvLalpilGlqlvldgtklvvetrwglva.iavavVfvgqLlrellr 59 al++++ i+G lv kl+ ++++++v ++++ +++g Ll++l + FUN_001640-T1 40 ALIVIFSIMGNSLVITAFKLNTNGKLRTVNnMFIVSMAAGDLLLTLGS 87 89**********************999997255566777888887765 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0011 DUF3382 24 qlvldgtklvvet........rwg...lvaiavavVfvgqLlrellrqalkarrklklleskvdgvlkltqrwillallvvA 94 +l+ + +++ +t w l+ ++ +Vfv++L +++ + ++++r +++ ++++ l+ r++ ++l +v+ FUN_001640-T1 177 NLKKKKGQISCKTrsffpnwkVWYlifLIVLGTTLVFVVSLYISIAIHVRRNKRPGCCMSVEGMKNVRLRSRILKMVLAIVL 258 55555555555555555544433300045566779*************9999887777766666666656666655554443 PP >> TMIE TMIE protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.4 0.00059 5 5 42 .. 192 230 .. 188 231 .. 0.76 2 ? 1.6 0.4 0.041 3.5e+02 8 33 .. 239 264 .. 235 266 .. 0.69 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.00059 TMIE 5 vfaglrvWqliai.vlgvvlaiviilCCiirfRiPRTkq 42 f++ +vW li++ vlg+ l++v+ l i + + R k+ FUN_001640-T1 192 FFPNWKVWYLIFLiVLGTTLVFVVSLYISIAIHVRRNKR 230 68899****998625677888888888888888877775 PP == domain 2 score: 1.6 bits; conditional E-value: 0.041 TMIE 8 glrvWqliaivlgvvlaiviilCCii 33 g++ +l +l +vlaiv+ C++ FUN_001640-T1 239 GMKNVRLRSRILKMVLAIVLAFYCCF 264 56666666667888999988776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (371 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1137 (0.0445097); expected 510.9 (0.02) Passed bias filter: 414 (0.0162067); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3645.70 // Query: FUN_001645-T1 [L=78] Description: FUN_001645 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.5e-05 23.7 0.0 7.2e-05 23.6 0.0 1.1 1 EF-hand_7 EF-hand domain pair 0.00022 21.2 0.0 0.016 15.4 0.0 2.5 2 EF-hand_6 EF-hand domain 0.0064 17.0 0.0 0.0067 16.9 0.0 1.2 1 EF-hand_SWAP70_N Switch-associated protein 70-like, N-termin ------ inclusion threshold ------ 0.044 13.8 0.0 1.3 9.2 0.0 2.5 3 EF-hand_1 EF hand domain Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.0 1.1e-08 7.2e-05 10 66 .. 22 76 .. 13 77 .. 0.92 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 1.1e-08 EF-hand_7 10 llDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 +lD++++G++++++l++l++ ++g++l +e++++++++ l + +i ++++++++ FUN_001645-T1 22 ALDREKTGSVSRSQLQHLMT--GTGDKLGSDEFDHMLRDLGLEGCVSIQYTDLVRAI 76 79******************..******************99999999999998876 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 2.5e-06 0.016 8 29 .. 22 43 .. 15 48 .. 0.85 2 ? 3.9 0.0 0.013 83 16 30 .] 46 60 .. 43 60 .. 0.88 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 2.5e-06 EF-hand_6 8 lfDkdgdGyisleElraalrsl 29 +D++++G++s+++l+++++ FUN_001645-T1 22 ALDREKTGSVSRSQLQHLMTGT 43 69*****************944 PP == domain 2 score: 3.9 bits; conditional E-value: 0.013 EF-hand_6 16 yisleElraalrslG 30 ++ +E+ ++lr lG FUN_001645-T1 46 KLGSDEFDHMLRDLG 60 67889*******998 PP >> EF-hand_SWAP70_N Switch-associated protein 70-like, N-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 1e-06 0.0067 9 36 .. 13 40 .. 8 73 .. 0.88 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1e-06 EF-hand_SWAP70_N 9 lksiwhaFtaLdveqsgkvsKsqLkVLs 36 +k i a taLd+e++g vs+sqL+ L FUN_001645-T1 13 EKEILPACTALDREKTGSVSRSQLQHLM 40 789999******************9775 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.0 0.0002 1.3 8 27 .. 22 41 .. 19 43 .. 0.90 2 ? 1.8 0.0 0.047 3e+02 17 28 .. 47 58 .. 46 59 .. 0.80 3 ? -2.4 0.0 1 6.5e+03 17 27 .. 67 77 .. 66 78 .] 0.73 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0002 EF-hand_1 8 efDkDgdGkIdfeEfkellk 27 +D+ + G ++++++++l++ FUN_001645-T1 22 ALDREKTGSVSRSQLQHLMT 41 58*****************8 PP == domain 2 score: 1.8 bits; conditional E-value: 0.047 EF-hand_1 17 IdfeEfkellkk 28 + +Ef ++l++ FUN_001645-T1 47 LGSDEFDHMLRD 58 6679****9997 PP == domain 3 score: -2.4 bits; conditional E-value: 1 EF-hand_1 17 IdfeEfkellk 27 I + +++++++ FUN_001645-T1 67 IQYTDLVRAIT 77 67788888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (78 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 435 (0.0170288); expected 510.9 (0.02) Passed bias filter: 415 (0.0162458); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.24u 0.37s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 823.59 // Query: FUN_001646-T1 [L=949] Description: FUN_001646 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0083 16.8 0.0 6.5 7.5 0.0 2.6 2 GLGE_C GLGE, C-terminal ------ inclusion threshold ------ 0.044 14.3 1.9 11 6.6 0.3 3.6 4 Type_III_YscG Bacterial type III secretion system chaperone 0.62 10.9 3.4 20 6.1 0.1 3.4 3 OMP10 Outer membrane lipoprotein Omp10 6.8 7.0 6.3 41 4.5 1.4 2.8 3 Rv3651-like_C Rv3651-like, C-terminal domain Domain annotation for each model (and alignments): >> GLGE_C GLGE, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.0 0.0023 15 53 79 .. 216 242 .. 205 247 .. 0.80 2 ! 7.5 0.0 0.001 6.5 30 76 .. 299 347 .. 282 350 .. 0.83 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0023 GLGE_C 53 sfevhDlltgeeyeWgeenyVrLdpek 79 + +Dl+t +y+ +e+nyV+Ld + FUN_001646-T1 216 DCISQDLITSGNYTGNEANYVSLDLIA 242 56679******************9665 PP == domain 2 score: 7.5 bits; conditional E-value: 0.001 GLGE_C 30 dphntqegtveldlealgleeee..sfevhDlltgeeyeWgeenyVrLd 76 +p+ +++ ++ldl a g ++++ ++ +Dl+++ +y+ +e nyV+Ld FUN_001646-T1 299 NPTGNEANCISLDLIADGNSTGNeaNCISSDLISNGNYTGNEVNYVSLD 347 567777888999999999877541167789*****************98 PP >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.86 5.5e+03 20 37 .. 210 227 .. 208 238 .. 0.58 2 ? 6.6 0.3 0.0017 11 11 48 .. 237 274 .. 228 285 .. 0.71 3 ? 3.6 0.1 0.015 93 14 38 .. 258 282 .. 255 299 .. 0.82 4 ? 3.1 0.0 0.021 1.3e+02 11 38 .. 309 336 .. 301 358 .. 0.79 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.86 Type_III_YscG 20 hcheeaniiaewlerkge 37 h +ea +i++ l + g+ FUN_001646-T1 210 HTGNEADCISQDLITSGN 227 666777777666555443 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0017 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgeeeaarlirlss 48 + l+ G h +ean+i+ l +g+ ++ +ss FUN_001646-T1 237 SLDLIADGTHTGNEANCISSDLIGNGNSAGSEANCISS 274 67899999999999999998888877765554444444 PP == domain 3 score: 3.6 bits; conditional E-value: 0.015 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkgee 38 l+G G+ ean+i+ l +g++ FUN_001646-T1 258 LIGNGNSAGSEANCISSDLIANGNH 282 89*************9988777665 PP == domain 4 score: 3.1 bits; conditional E-value: 0.021 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgee 38 + l+ G+ +ean+i+ l ++g+ FUN_001646-T1 309 SLDLIADGNSTGNEANCISSDLISNGNY 336 5789999***********9998887764 PP >> OMP10 Outer membrane lipoprotein Omp10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.1 0.0031 20 27 62 .. 219 254 .. 210 258 .. 0.88 2 ? 1.1 0.1 0.11 7.1e+02 16 61 .. 278 325 .. 261 330 .. 0.61 3 ? 2.2 0.2 0.049 3.1e+02 28 60 .. 328 360 .. 314 362 .. 0.85 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0031 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskvnCa 62 +++ +++G+Yt ++a+ v+++l ++t ++nC FUN_001646-T1 219 SQDLITSGNYTGNEANYVSLDLIADGTHTGNEANCI 254 566789*****************************6 PP == domain 2 score: 1.1 bits; conditional E-value: 0.11 OMP10 16 snGrFetratd..tgekLaeGtYtktsaklveieltslvrktqskvnC 61 +nG+ + ++++ + + +a G+ t ++a+ ++++l + t ++nC FUN_001646-T1 278 ANGNHNGNEANyeSLDLIAIGNPTGNEANCISLDLIADGNSTGNEANC 325 455555554442233456666666666666666666666666666666 PP == domain 3 score: 2.2 bits; conditional E-value: 0.049 OMP10 28 gekLaeGtYtktsaklveieltslvrktqskvn 60 + +++G+Yt ++ + v+++l + ++t ++n FUN_001646-T1 328 SDLISNGNYTGNEVNYVSLDLIAIGNQTGNEAN 360 56789****************999999887776 PP >> Rv3651-like_C Rv3651-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.1 0.0082 53 22 77 .. 568 623 .. 561 633 .. 0.71 2 ? 4.5 1.4 0.0064 41 27 56 .. 635 663 .. 630 672 .. 0.81 3 ? -3.5 0.0 1.9 1.2e+04 15 27 .. 694 706 .. 691 727 .. 0.77 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0082 Rv3651-like_C 22 dlkswkllkwldepcPfldwraeekeesvvhPddeaelasmaaefatGatsrvlrl 77 d sw++ k ld+ +l+wr ++ + + + a ma tG+ +++ l FUN_001646-T1 568 DDSSWNFAKLLDHCNEYLNWRRSSDVSLRTESLLIAMEICMAGSNKTGPETKLCAL 623 7789*****************98865555554444444456666666666655555 PP == domain 2 score: 4.5 bits; conditional E-value: 0.0064 Rv3651-like_C 27 kllkwldepcPfldwraeekeesvvhPdde 56 ++ kw ++ P+l+wr ++ + + +P+d+ FUN_001646-T1 635 RITKWWNNCWPYLEWRKSNVSV-QTDPQDN 663 678*************999654.4577775 PP == domain 3 score: -3.5 bits; conditional E-value: 1.9 Rv3651-like_C 15 gvhralvdlkswk 27 +++ +vd+k w FUN_001646-T1 694 NIYHKIVDIKRWI 706 6889999**9995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (949 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1591 (0.0622822); expected 510.9 (0.02) Passed bias filter: 497 (0.0194559); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.47u 0.42s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 8825.10 // Query: FUN_001647-T1 [L=132] Description: FUN_001647 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.025 14.6 1.2 0.032 14.2 1.2 1.1 1 TBK1_CCD1 TANK-binding kinase 1 coiled-coil domain 1 0.084 11.7 1.2 0.092 11.5 1.2 1.0 1 WDCP WD repeat and coiled-coil-containing protein famil 0.17 12.9 0.7 0.25 12.4 0.6 1.4 1 MRFAP1 MORF4 family-associated protein1 0.25 12.5 1.3 0.5 11.5 1.3 1.6 1 SMAP Small acidic protein family 3.5 8.0 6.5 0.78 10.1 0.8 2.3 2 DivIC Septum formation initiator Domain annotation for each model (and alignments): >> TBK1_CCD1 TANK-binding kinase 1 coiled-coil domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 1.2 6.3e-06 0.032 55 124 .. 61 128 .. 51 131 .. 0.84 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 6.3e-06 TBK1_CCD1 55 vnkllhkktevelkleicnetiekaekllealmqlnlepsEldeiselrkkllrlsssldrlseslqeik 124 +++lh ++e + + + +++iek+++ + +n+ p+ +e+ l+ k+lrl+++ ++l++++ e++ FUN_001647-T1 61 KRQTLHGNLETQYDETLTKRHIEKEKQ--ATSIANNPLPEADKEVLRLQGKVLRLQEKIAKLQHKVAELQ 128 46789********************94..444566777756778**********************9987 PP >> WDCP WD repeat and coiled-coil-containing protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 1.2 1.8e-05 0.092 503 602 .. 33 129 .. 4 131 .. 0.74 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 1.8e-05 WDCP 503 seqsplssvvdlsekklssessvaletldaepvnrsaalakasstseesstpespkleleelekkknlekekeaeqlskelerlsrkltelqqcls 598 +eqs++ ++ + ++ e++v+ +tl+++ + + +l++ + + ++++ +++ + ++ ++ e +ke+ +l ++ rl +k+++lq++++ FUN_001647-T1 33 YEQSSKETPNN--VHDVKPERAVTNQTLKKKRQTLHGNLET-QYDETLTKRHIEKEKQATSIANNPLPEADKEVLRLQGKVLRLQEKIAKLQHKVA 125 33443333333..3446677888888887777777777744.455566677777777777888999999*************************** PP WDCP 599 eltd 602 el+ FUN_001647-T1 126 ELQG 129 *985 PP >> MRFAP1 MORF4 family-associated protein1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.6 4.9e-05 0.25 62 110 .. 81 128 .. 42 130 .. 0.86 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.9e-05 MRFAP1 62 eveaseesaldparsPgaeaeervaklcakaerkakeaarmgkrivelh 110 ++e +e+ a a++P ea++ v +l k+ r +a++ +++ el+ FUN_001647-T1 81 HIE-KEKQATSIANNPLPEADKEVLRLQGKVLRLQEKIAKLQHKVAELQ 128 444.588999***********************************9995 PP >> SMAP Small acidic protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 1.3 9.8e-05 0.5 36 66 .. 51 81 .. 24 89 .. 0.71 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.8e-05 SMAP 36 akanmalskkkqeklqqdLekQyeaamkkke 66 ++ + ++ kkk+++l +Le Qy++ + k++ FUN_001647-T1 51 RAVTNQTLKKKRQTLHGNLETQYDETLTKRH 81 45566778999**************999433 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.5 0.11 5.4e+02 21 39 .. 46 64 .. 23 85 .. 0.71 2 ? 10.1 0.8 0.00015 0.78 23 51 .. 100 128 .. 96 131 .. 0.83 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.11 DivIC 21 qlkqeiaeleaeiaklkae 39 ++k e+a +++++k+++ FUN_001647-T1 46 DVKPERAVTNQTLKKKRQT 64 5555555555555555553 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00015 DivIC 23 kqeiaeleaeiaklkaeneeLeaeikdLk 51 ++e+ +l+ ++ +l++++++L++++++L+ FUN_001647-T1 100 DKEVLRLQGKVLRLQEKIAKLQHKVAELQ 128 68889999999999999999999999883 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2178 (0.0852613); expected 510.9 (0.02) Passed bias filter: 896 (0.0350754); expected 510.9 (0.02) Passed Vit filter: 89 (0.00348405); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1331.43 // Query: FUN_001648-T1 [L=209] Description: FUN_001648 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-36 123.6 4.2 1.1e-35 123.2 4.2 1.1 1 Mt_ATP-synt_B Mitochondrial ATP synthase B chain precur ------ inclusion threshold ------ 0.12 11.8 0.7 0.14 11.5 0.7 1.1 1 Fas1-AflB-like_hel Fatty acid synthase subunit beta/Fas1-lik 0.2 12.6 0.9 29 5.8 0.0 2.9 4 ATP-synt_ab_N ATP synthase alpha/beta family, beta-barr 0.25 12.7 2.3 0.66 11.4 0.5 2.3 2 DUF4845 Domain of unknown function (DUF4845) Domain annotation for each model (and alignments): >> Mt_ATP-synt_B Mitochondrial ATP synthase B chain precursor (ATP-synt_B) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 123.2 4.2 1.7e-39 1.1e-35 2 163 .] 44 204 .. 43 204 .. 0.99 Alignments for each domain: == domain 1 score: 123.2 bits; conditional E-value: 1.7e-39 Mt_ATP-synt_B 2 iayliSkeiyvvneEtlvalcfigflilvakslgpsikefldkriekiqdelnesrnekeealkerieqekklqslveetkslfevskeqvaleae 97 +ay++Ske++v+++Et++a+ + l+++a+++++ i+++ld+r+++i d +ne rn +++ ++ ie+ kk ++ ++k+++ +e+ a+ +e FUN_001648-T1 44 LAYSLSKELLVIHDETVLAVVMGTTLYFLAQKVSKPIADMLDARYQSILDMFNEGRNAEIQGITNQIEELKKIEYMSTVRKDVIGIYRENNAMSLE 139 69********************************************************************************************** PP Mt_ATP-synt_B 98 aaerelqaklareikkkldtlvelesskrqreQdelvkgvissVlkelsspkfkkevlqesiadle 163 +r+ +++ re+kk+ld++ e e +r+ eQ +++++v+ V+k++ +p+++ke++ ++++dl+ FUN_001648-T1 140 LDYRNKLHEVVREVKKRLDYQAEIETFQRRTEQLHIIDWVEREVVKSI-TPQLEKESVSQCLKDLK 204 ************************************************.***************97 PP >> Fas1-AflB-like_hel Fatty acid synthase subunit beta/Fas1-like, helical # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.7 2.2e-05 0.14 157 251 .. 82 172 .. 44 205 .. 0.72 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 2.2e-05 Fas1-AflB-like_hel 157 aalekkrdeiierlnkdyakpwfavdeegelveleemtYsevvrRlveLaflksrkewidpswkklfqdllqrveeRleaeehgeaeslle 247 +l+++ ++i++ +n+ + ++ + ++ el++++Y vr+ v ++ +++ ++ +++ +++++++v++Rl+ ++ e+e+ + FUN_001648-T1 82 DMLDARYQSILDMFNEGRNAEIQGI--TNQIEELKKIEYMSTVRKDVIGIYRENNAMSLELDYRNKLHEVVREVKKRLDYQA--EIETFQR 168 4677777888888888866666655..445569************9999999*9************************5543..3443333 PP Fas1-AflB-like_hel 248 svea 251 +e+ FUN_001648-T1 169 RTEQ 172 3333 PP >> ATP-synt_ab_N ATP synthase alpha/beta family, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 3.8 2.4e+04 33 45 .. 30 42 .. 27 45 .. 0.68 2 ? 4.1 0.0 0.015 93 43 56 .. 55 68 .. 48 70 .. 0.87 3 ? -1.8 0.0 1 6.6e+03 18 43 .. 80 106 .. 73 109 .. 0.70 4 ? 5.8 0.0 0.0045 29 12 42 .. 124 152 .. 121 156 .. 0.84 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 3.8 ATP-synt_ab_N 33 gslvlgevlnlee 45 +++ g+vl +++ FUN_001648-T1 30 KTGETGQVLLIGG 42 5666777777765 PP == domain 2 score: 4.1 bits; conditional E-value: 0.015 ATP-synt_ab_N 43 leedkVriqvfegt 56 +++++V+++v++ t FUN_001648-T1 55 IHDETVLAVVMGTT 68 799*********98 PP == domain 3 score: -1.8 bits; conditional E-value: 1 ATP-synt_ab_N 18 lpgllnalevelve.fgslvlgevlnl 43 ++ +l+a + +++ f++++ +e++++ FUN_001648-T1 80 IADMLDARYQSILDmFNEGRNAEIQGI 106 556666666667777889999999987 PP == domain 4 score: 5.8 bits; conditional E-value: 0.0045 ATP-synt_ab_N 12 edgigrlpgllnalevelvefgslvlgevln 42 +d+ig ++ ++na+++el +++ ++v + FUN_001648-T1 124 KDVIG-IYRENNAMSLELDY-RNKLHEVVRE 152 68899.***********777.9999998855 PP >> DUF4845 Domain of unknown function (DUF4845) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.5 0.0001 0.66 25 73 .. 98 146 .. 85 150 .. 0.88 2 ? 0.7 0.1 0.22 1.4e+03 30 47 .. 150 167 .. 144 188 .. 0.75 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0001 DUF4845 25 legmskaeirssldkrldinnvrsikgedleiekeggkvvvsvdYevrv 73 ++++ + i ++++ +i++ ++++++ + i +e++ +++++dY+ + FUN_001648-T1 98 GRNAEIQGITNQIEELKKIEYMSTVRKDVIGIYRENNAMSLELDYRNKL 146 56778889999**********************************9875 PP == domain 2 score: 0.7 bits; conditional E-value: 0.22 DUF4845 30 kaeirssldkrldinnvr 47 ++e++++ld +++i+ + FUN_001648-T1 150 VREVKKRLDYQAEIETFQ 167 688899999999888763 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (209 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1801 (0.070503); expected 510.9 (0.02) Passed bias filter: 952 (0.0372676); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2111.34 // Query: FUN_001648-T2 [L=241] Description: FUN_001648 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-35 122.9 4.2 1.7e-35 122.6 4.2 1.1 1 Mt_ATP-synt_B Mitochondrial ATP synthase B chain precur ------ inclusion threshold ------ 0.13 11.7 0.3 0.16 11.4 0.3 1.1 1 Fas1-AflB-like_hel Fatty acid synthase subunit beta/Fas1-lik 0.2 12.7 0.2 35 5.5 0.0 2.9 3 ATP-synt_ab_N ATP synthase alpha/beta family, beta-barr 0.31 12.4 2.0 0.89 11.0 0.5 2.2 2 DUF4845 Domain of unknown function (DUF4845) Domain annotation for each model (and alignments): >> Mt_ATP-synt_B Mitochondrial ATP synthase B chain precursor (ATP-synt_B) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 122.6 4.2 2.6e-39 1.7e-35 2 163 .] 76 236 .. 75 236 .. 0.99 Alignments for each domain: == domain 1 score: 122.6 bits; conditional E-value: 2.6e-39 Mt_ATP-synt_B 2 iayliSkeiyvvneEtlvalcfigflilvakslgpsikefldkriekiqdelnesrnekeealkerieqekklqslveetkslfevskeqvaleae 97 +ay++Ske++v+++Et++a+ + l+++a+++++ i+++ld+r+++i d +ne rn +++ ++ ie+ kk ++ ++k+++ +e+ a+ +e FUN_001648-T2 76 LAYSLSKELLVIHDETVLAVVMGTTLYFLAQKVSKPIADMLDARYQSILDMFNEGRNAEIQGITNQIEELKKIEYMSTVRKDVIGIYRENNAMSLE 171 69********************************************************************************************** PP Mt_ATP-synt_B 98 aaerelqaklareikkkldtlvelesskrqreQdelvkgvissVlkelsspkfkkevlqesiadle 163 +r+ +++ re+kk+ld++ e e +r+ eQ +++++v+ V+k++ +p+++ke++ ++++dl+ FUN_001648-T2 172 LDYRNKLHEVVREVKKRLDYQAEIETFQRRTEQLHIIDWVEREVVKSI-TPQLEKESVSQCLKDLK 236 ************************************************.***************97 PP >> Fas1-AflB-like_hel Fatty acid synthase subunit beta/Fas1-like, helical # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.3 2.4e-05 0.16 157 251 .. 114 204 .. 73 237 .. 0.72 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 2.4e-05 Fas1-AflB-like_hel 157 aalekkrdeiierlnkdyakpwfavdeegelveleemtYsevvrRlveLaflksrkewidpswkklfqdllqrveeRleaeehgeaeslle 247 +l+++ ++i++ +n+ + ++ + ++ el++++Y vr+ v ++ +++ ++ +++ +++++++v++Rl+ ++ e+e+ + FUN_001648-T2 114 DMLDARYQSILDMFNEGRNAEIQGI--TNQIEELKKIEYMSTVRKDVIGIYRENNAMSLELDYRNKLHEVVREVKKRLDYQA--EIETFQR 200 4677777888888888866666655..445569************9999999*9************************5543..3443333 PP Fas1-AflB-like_hel 248 svea 251 +e+ FUN_001648-T2 201 RTEQ 204 3333 PP >> ATP-synt_ab_N ATP synthase alpha/beta family, beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.018 1.1e+02 43 56 .. 87 100 .. 80 102 .. 0.87 2 ? -2.1 0.0 1.3 8.1e+03 18 43 .. 112 138 .. 105 141 .. 0.70 3 ? 5.5 0.0 0.0055 35 12 42 .. 156 184 .. 153 188 .. 0.84 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.018 ATP-synt_ab_N 43 leedkVriqvfegt 56 +++++V+++v++ t FUN_001648-T2 87 IHDETVLAVVMGTT 100 799*********98 PP == domain 2 score: -2.1 bits; conditional E-value: 1.3 ATP-synt_ab_N 18 lpgllnalevelve.fgslvlgevlnl 43 ++ +l+a + +++ f++++ +e++++ FUN_001648-T2 112 IADMLDARYQSILDmFNEGRNAEIQGI 138 556666666666777889999999987 PP == domain 3 score: 5.5 bits; conditional E-value: 0.0055 ATP-synt_ab_N 12 edgigrlpgllnalevelvefgslvlgevln 42 +d+ig ++ ++na+++el +++ ++v + FUN_001648-T2 156 KDVIG-IYRENNAMSLELDY-RNKLHEVVRE 184 68899.***********777.9999998855 PP >> DUF4845 Domain of unknown function (DUF4845) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.5 0.00014 0.89 25 73 .. 130 178 .. 118 182 .. 0.88 2 ? 0.6 0.1 0.25 1.6e+03 30 47 .. 182 199 .. 175 220 .. 0.75 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00014 DUF4845 25 legmskaeirssldkrldinnvrsikgedleiekeggkvvvsvdYevrv 73 ++++ + i ++++ +i++ ++++++ + i +e++ +++++dY+ + FUN_001648-T2 130 GRNAEIQGITNQIEELKKIEYMSTVRKDVIGIYRENNAMSLELDYRNKL 178 56777889999**********************************9875 PP == domain 2 score: 0.6 bits; conditional E-value: 0.25 DUF4845 30 kaeirssldkrldinnvr 47 ++e++++ld +++i+ + FUN_001648-T2 182 VREVKKRLDYQAEIETFQ 199 688899999999888763 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (241 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1405 (0.055001); expected 510.9 (0.02) Passed bias filter: 804 (0.0314739); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.43s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2357.55 // Query: FUN_001649-T1 [L=462] Description: FUN_001649 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-46 157.4 2.5 1e-45 156.9 2.5 1.2 1 Glycos_transf_3 Glycosyl transferase family, a/b domain 1.3e-18 67.0 0.1 2.7e-18 66.0 0.1 1.6 1 Glycos_trans_3N Glycosyl transferase family, helical bundle 1.9e-14 53.6 0.2 5.5e-14 52.1 0.2 1.9 1 PYNP_C Pyrimidine nucleoside phosphorylase C-termin ------ inclusion threshold ------ 0.045 13.0 0.0 0.19 11.0 0.0 1.9 1 DUF2254 Predicted membrane protein (DUF2254) 0.24 11.8 0.0 0.92 9.9 0.0 2.0 2 Gag_p24 gag protein p24 N-terminal domain Domain annotation for each model (and alignments): >> Glycos_transf_3 Glycosyl transferase family, a/b domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 156.9 2.5 2e-49 1e-45 3 253 .] 83 312 .. 81 312 .. 0.98 Alignments for each domain: == domain 1 score: 156.9 bits; conditional E-value: 2e-49 Glycos_transf_3 3 dlvDkvgTGGdgantiNiSttaaivvAaaGvkvakhgnrsvssksGsaDvLeal.gvnleltpekvkklleevgvgflfapeyhpamkhvapvr 95 ++Dk++TGG+g+++ S+ +a+ +A +Gvkv+++++rs+++++G++D+Le++ g++++ ++ ++ +++++vg+++++++ ++++v++ FUN_001649-T1 83 SVADKHSTGGVGDKV---SLPLAPALAVCGVKVPMISGRSLGHTGGTLDKLESIrGFQVNIDSKRICEIVQKVGCCIVGQTDAMVPADKVLYSM 173 689***********9...**************************************************************************** PP Glycos_transf_3 96 relkirTvfnllGPLinparvkkqvlgvlskelaeklaevlkdlkvkralvvhgsGldelsllaktlvaelk.dgeieeatltpedfglkrael 188 r++++ Tv ++ PLi++ +++sk+ +e+ a+++ d+k ++a++ ++ ++ + +la++lv g + +t++d +l++a + FUN_001649-T1 174 RDVTA-TVSSM--PLISS--------SIISKKACENPAALVLDVKCGKAAFATT--EEFAHALAQSLVGTCSgLGIKAVVLITAMDAPLGSAIG 254 *****.*****..*****........****************************..888999**********8999999999************ PP Glycos_transf_3 189 ealeggepkenaeilkavlegkesaakadlvvlnagallvlagkadslkegvakaeevldsGkAl 253 +++e+ e++ +l+++ g++++ +lv +g ll++ +ka+s+++g++ + ++l+sG+Al FUN_001649-T1 255 NSVEV---AEAISCLNGE--GPHDL--KELVCKEGGHLLYTLKKAESVEDGAKCITDALESGQAL 312 *****...*********9..99998..7***********************************96 PP >> Glycos_trans_3N Glycosyl transferase family, helical bundle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.0 0.1 5.4e-22 2.7e-18 2 63 .] 10 71 .. 9 71 .. 0.98 Alignments for each domain: == domain 1 score: 66.0 bits; conditional E-value: 5.4e-22 Glycos_trans_3N 2 elikklrdgedLteeeaeeamdgimsgeasdaQiaAfLmAlrfkGetaeEiaglaramresa 63 +li k+rdg++L+e+e+ +++ +++ +a d Qi+A+LmA++++G+t+ E+++l++am+ s+ FUN_001649-T1 10 DLIVKKRDGKELSEDEINHFVKCVTTKSALDGQIGAMLMAIYLNGMTSVETVHLTKAMMTSG 71 89*********************************************************987 PP >> PYNP_C Pyrimidine nucleoside phosphorylase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.1 0.2 1.1e-17 5.5e-14 2 74 .. 360 431 .. 359 432 .. 0.97 Alignments for each domain: == domain 1 score: 52.1 bits; conditional E-value: 1.1e-17 PYNP_C 2 vssidareiGlaaveLGAGRakkeDpidlevGielhkklGdkVkkGeplatiYankeekleeavkklkkaiei 74 v++ida +++++ +LGAGR +e id++vGi+l +++G+ ++k at+Y+n + ++++ + ++kai++ FUN_001649-T1 360 VKEIDALALAIVTNKLGAGRDEPEGSIDHGVGIVLCVRVGQFIEKSRKWATVYHNGNL-NDSLKTSVEKAIKV 431 89*******************************************************9.*********99986 PP >> DUF2254 Predicted membrane protein (DUF2254) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 3.7e-05 0.19 194 266 .. 348 434 .. 302 445 .. 0.73 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 3.7e-05 DUF2254 194 eatsvkakrsGylqaidvdaLvklaee.............hdlvirlevrpGdfvvegeplakvwgee.edeeleeelrkafaigre 266 ++t+++ak+sG +++id aL + ++ h++ i l+vr+G+f+ + ++ a+v+++ +++l+ ++ka+ + ++ FUN_001649-T1 348 RKTELFAKKSGIVKEIDALALAIVTNKlgagrdepegsidHGVGIVLCVRVGQFIEKSRKWATVYHNGnLNDSLKTSVEKAIKVDQN 434 5666677777777777777666544322222222222222999**********************9999778999999999988764 PP >> Gag_p24 gag protein p24 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00018 0.92 12 69 .. 28 84 .. 19 98 .. 0.81 2 ? -3.5 0.0 2.5 1.3e+04 67 96 .. 403 440 .. 400 443 .. 0.54 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00018 Gag_p24 12 elkkavkeyGlnspftlqlleslaesnaltPsDwrtlakavlspgqyllwkaeweeea 69 + +k v+++++ + ++l ++ n +t +l+ka++++g+ l+w +ew+ + FUN_001649-T1 28 HFVKCVTTKSALDGQIGAMLMAIYL-NGMTSVETVHLTKAMMTSGESLMWPTEWKGSV 84 5556666666666667788888885.999*************************9765 PP == domain 2 score: -3.5 bits; conditional E-value: 2.5 Gag_p24 67 eeareqaernqragpda.........gvtldmLlGtgqy 96 e+ r++a+ ++g+ + +++d+ +Gt+++ FUN_001649-T1 403 EKSRKWATVY-HNGNLNdslktsvekAIKVDQNAGTEDF 440 5556666666.3332222454445556667777777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (462 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 621 (0.02431); expected 510.9 (0.02) Passed bias filter: 531 (0.0207868); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 4606.76 // Query: FUN_001650-T1 [L=103] Description: FUN_001650 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 993 (0.0388726); expected 510.9 (0.02) Passed bias filter: 674 (0.0263848); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1040.98 // Query: FUN_001651-T1 [L=462] Description: FUN_001651 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-45 155.6 2.7 3.6e-45 155.1 2.7 1.2 1 Glycos_transf_3 Glycosyl transferase family, a/b domain 6.9e-19 67.9 0.0 1.5e-18 66.8 0.0 1.6 1 Glycos_trans_3N Glycosyl transferase family, helical bundle 3.2e-14 52.8 0.1 1.1e-13 51.1 0.1 2.0 1 PYNP_C Pyrimidine nucleoside phosphorylase C-termin ------ inclusion threshold ------ 0.12 11.6 0.0 0.52 9.5 0.0 1.9 1 DUF2254 Predicted membrane protein (DUF2254) 0.24 11.8 0.0 0.92 9.9 0.0 1.9 2 Gag_p24 gag protein p24 N-terminal domain Domain annotation for each model (and alignments): >> Glycos_transf_3 Glycosyl transferase family, a/b domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 155.1 2.7 7e-49 3.6e-45 3 253 .] 83 312 .. 81 312 .. 0.98 Alignments for each domain: == domain 1 score: 155.1 bits; conditional E-value: 7e-49 Glycos_transf_3 3 dlvDkvgTGGdgantiNiSttaaivvAaaGvkvakhgnrsvssksGsaDvLeal.gvnleltpekvkklleevgvgflfapeyhpamkhvapvr 95 ++Dk++TGG+g+++ S+ +a+ +A +Gvkv+++++rs+++++G++D+Le++ g++++ ++ ++ +++++vg+++++++ ++++v++ FUN_001651-T1 83 SVADKHSTGGVGDKV---SLPLAPALAVCGVKVPMISGRSLGHTGGTLDKLESIrGFQVNIDSKRICEIVQKVGCCIVGQTDAMVPADKVLYSM 173 689***********9...**************************************************************************** PP Glycos_transf_3 96 relkirTvfnllGPLinparvkkqvlgvlskelaeklaevlkdlkvkralvvhgsGldelsllaktlvaelk.dgeieeatltpedfglkrael 188 r++++ Tv ++ PLi++ +++sk+ +e+ +++ d+k ++a++ ++ ++ + +la++lv g + + +t++d +l++a + FUN_001651-T1 174 RDVTA-TVSSM--PLISS--------SIISKKACENPTALVLDVKCGKAAFATT--EEFAHALAQSLVGTCSgLGIQAVVLITAMDAPLGSAVG 254 *****.*****..*****........****************************..888999**********9999999*************** PP Glycos_transf_3 189 ealeggepkenaeilkavlegkesaakadlvvlnagallvlagkadslkegvakaeevldsGkAl 253 +++e+ e++ +l+++ g++++ +lv +g ll++ +ka+s+++g++ ++++l+sG+Al FUN_001651-T1 255 NSVEV---AEAISCLNGE--GPHDL--KELVCKEGGHLLYTLKKAESVEDGAKCIADALESGQAL 312 *****...*********9..99998..7***********************************96 PP >> Glycos_trans_3N Glycosyl transferase family, helical bundle domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.8 0.0 2.9e-22 1.5e-18 2 63 .] 10 71 .. 9 71 .. 0.98 Alignments for each domain: == domain 1 score: 66.8 bits; conditional E-value: 2.9e-22 Glycos_trans_3N 2 elikklrdgedLteeeaeeamdgimsgeasdaQiaAfLmAlrfkGetaeEiaglaramresa 63 +li k+rdg++L+e+e+ +++ +++ ++ d Qi+A+LmA++++G+t+ E+++l++am+ s+ FUN_001651-T1 10 DLIVKKRDGKELSEDEINHFVKCVTTKSVLDCQIGAMLMAIYLNGMTSVETVHLTKAMMTSG 71 89*********************************************************987 PP >> PYNP_C Pyrimidine nucleoside phosphorylase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.1 0.1 2.1e-17 1.1e-13 2 74 .. 360 431 .. 359 432 .. 0.97 Alignments for each domain: == domain 1 score: 51.1 bits; conditional E-value: 2.1e-17 PYNP_C 2 vssidareiGlaaveLGAGRakkeDpidlevGielhkklGdkVkkGeplatiYankeekleeavkklkkaiei 74 v++ida +++++ +LGAGR +e id++vGi+l ++G+ ++k at+Y+n + ++++ + ++kai++ FUN_001651-T1 360 VKEIDALALAIVTNKLGAGRDEPEGSIDHGVGIVLCIRVGQFIEKSSKWATVYHNGNL-NDSLKTSVEKAIKV 431 89*******************************************************9.**********9986 PP >> DUF2254 Predicted membrane protein (DUF2254) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.0 0.0001 0.52 195 266 .. 349 434 .. 315 445 .. 0.73 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0001 DUF2254 195 atsvkakrsGylqaidvdaLvklaee.............hdlvirlevrpGdfvvegeplakvwgee.edeeleeelrkafaigre 266 +t+++ak+sG +++id aL + ++ h++ i l+ r+G+f+ + ++ a+v+++ +++l+ ++ka+ ++++ FUN_001651-T1 349 KTELFAKKSGIVKEIDALALAIVTNKlgagrdepegsidHGVGIVLCIRVGQFIEKSSKWATVYHNGnLNDSLKTSVEKAIKVEQN 434 5566666666666666666654433211122222222228999*********************9999778999999999998765 PP >> Gag_p24 gag protein p24 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00018 0.92 11 69 .. 27 84 .. 19 98 .. 0.81 2 ? -2.6 0.0 1.3 6.7e+03 27 49 .. 311 333 .. 301 334 .. 0.74 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00018 Gag_p24 11 kelkkavkeyGlnspftlqlleslaesnaltPsDwrtlakavlspgqyllwkaeweeea 69 ++ +k v+++++ + ++l ++ n +t +l+ka++++g+ l+w +ew+ + FUN_001651-T1 27 NHFVKCVTTKSVLDCQIGAMLMAIYL-NGMTSVETVHLTKAMMTSGESLMWPTEWKGSV 84 55566666666666667788988885.999*************************9765 PP == domain 2 score: -2.6 bits; conditional E-value: 1.3 Gag_p24 27 tlqlleslaesnaltPsDwrtla 49 +l ++ ++e++ ++P D ++l+ FUN_001651-T1 311 ALYKFREMLEAQGVLPEDAQKLC 333 55556777788999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (462 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 610 (0.0238794); expected 510.9 (0.02) Passed bias filter: 515 (0.0201605); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4546.53 // Query: FUN_001652-T1 [L=618] Description: FUN_001652 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-09 36.9 0.0 0.00038 20.3 0.0 2.8 2 EF-hand_1 EF hand domain 2.1e-08 34.8 0.1 0.0063 17.3 0.0 3.0 3 EF-hand_7 EF-hand domain pair 7.4e-08 32.0 0.0 0.001 19.1 0.0 2.9 2 EF-hand_6 EF-hand domain 1.8e-06 27.7 0.0 0.00093 19.1 0.0 2.6 2 EF-hand_5 EF hand 0.00012 22.2 0.0 0.033 14.4 0.0 2.6 2 EF-hand_8 EF-hand domain pair ------ inclusion threshold ------ 0.13 13.3 0.1 0.31 12.1 0.1 1.6 1 Desulfoferrodox Desulfoferrodoxin Domain annotation for each model (and alignments): >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 8.9e-08 0.00038 4 24 .. 447 467 .. 444 471 .. 0.90 2 ! 13.6 0.0 1.2e-05 0.051 2 28 .. 535 561 .. 534 562 .. 0.92 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 8.9e-08 EF-hand_1 4 eiFrefDkDgdGkIdfeEfke 24 +Fr++D+D dG+I+f E+k+ FUN_001652-T1 447 TAFRKLDTDCDGHISFPELKK 467 69*****************97 PP == domain 2 score: 13.6 bits; conditional E-value: 1.2e-05 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkk 28 + e Fre+D+++ G Id++ f +ll+k FUN_001652-T1 535 FMESFREADVNQRGVIDRQSFETLLAK 561 6799*****************999987 PP >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.1 2 8.6e+03 34 53 .. 378 397 .. 363 400 .. 0.74 2 ! 17.3 0.0 1.5e-06 0.0063 2 26 .. 443 467 .. 433 485 .. 0.67 3 ! 14.0 0.0 1.6e-05 0.067 4 64 .. 535 595 .. 532 597 .. 0.82 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 2 EF-hand_7 34 geplsdeeveelfkefDldk 53 ++++++++ ee+++++D+ + FUN_001652-T1 378 SNSIHQDANEEVIEMIDVEN 397 55666777789999999876 PP == domain 2 score: 17.3 bits; conditional E-value: 1.5e-06 EF-hand_7 2 eklkeaFkllDsdgdGyldveelkk 26 + l +aF++lD+d+dG+++ elkk FUN_001652-T1 443 SVLATAFRKLDTDCDGHISFPELKK 467 4566777777777777777777553 PP == domain 3 score: 14.0 bits; conditional E-value: 1.6e-05 EF-hand_7 4 lkeaFkllDsdgdGyldveelkkllrkleegeplsdee..veelfkefDldkdGrisfeEFle 64 +e F++ D++++G +d++ ++ ll k +++p ++ + +++++ ++ ++ d++is E+l+ FUN_001652-T1 535 FMESFREADVNQRGVIDRQSFETLLAKV-INIP-QPNSlvIQTVLSNLRKSADDTISGVELLA 595 5899******************999984.4444.4444459***************9888876 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 2.5e-07 0.001 4 25 .. 447 468 .. 444 471 .. 0.90 2 ! 9.7 0.0 0.00025 1.1 2 27 .. 535 560 .. 534 563 .. 0.90 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 2.5e-07 EF-hand_6 4 eaFklfDkdgdGyisleElraa 25 aF+++D+d dG+is+ El++ FUN_001652-T1 447 TAFRKLDTDCDGHISFPELKKS 468 69*****************985 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00025 EF-hand_6 2 lreaFklfDkdgdGyisleElraalr 27 ++e F+ D+++ G i+++ + +l FUN_001652-T1 535 FMESFREADVNQRGVIDRQSFETLLA 560 6899*****************99986 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 2.2e-07 0.00093 2 23 .. 446 467 .. 445 469 .. 0.90 2 ! 6.0 0.0 0.003 13 4 19 .. 538 553 .. 535 559 .. 0.82 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 2.2e-07 EF-hand_5 2 kdtFraiDlNgDGkIskeELkr 23 ++Fr++D++ DG Is+ ELk+ FUN_001652-T1 446 ATAFRKLDTDCDGHISFPELKK 467 568*****************97 PP == domain 2 score: 6.0 bits; conditional E-value: 0.003 EF-hand_5 4 tFraiDlNgDGkIske 19 Fr++D+N+ G I+++ FUN_001652-T1 538 SFREADVNQRGVIDRQ 553 4************987 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.0 7.7e-06 0.033 21 48 .. 437 466 .. 409 471 .. 0.73 2 ! 4.8 0.0 0.0077 33 32 48 .. 540 556 .. 538 578 .. 0.55 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 7.7e-06 EF-hand_8 21 d..lsedevdtlfrefDtDgdGkisfeeFc 48 + ++ + t fr +DtD+dG+isf e++ FUN_001652-T1 437 HevPVDSVLATAFRKLDTDCDGHISFPELK 466 365556778999**************9876 PP == domain 2 score: 4.8 bits; conditional E-value: 0.0077 EF-hand_8 32 refDtDgdGkisfeeFc 48 re+D ++ G+i+ +F FUN_001652-T1 540 READVNQRGVIDRQSFE 556 55555555555555553 PP >> Desulfoferrodox Desulfoferrodoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 7.4e-05 0.31 5 62 .. 351 408 .. 347 436 .. 0.80 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 7.4e-05 Desulfoferrodox 5 keekHvPvieapdsvkagelfevkvsvgkiaHpneeeHhIewielyfeeegekraela 62 +e++ P+i+ ++vk+g ++ ++ + ++ H + +e Ie+i++ +e+e+++r++ + FUN_001652-T1 351 TEKTSPPMIDPTEEVKEGTMICLQDRASNSIHQDANEEVIEMIDVENEKEKDNRVQPE 408 4455679******************************************999987644 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (618 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1731 (0.0677628); expected 510.9 (0.02) Passed bias filter: 701 (0.0274418); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5985.63 // Query: FUN_001653-T1 [L=453] Description: FUN_001653 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.2e-51 174.2 24.3 1.4e-50 173.0 24.3 1.4 1 CLN3 CLN3 protein 1.2e-05 24.9 7.0 1.2e-05 24.9 7.0 3.2 3 MFS_1 Major Facilitator Superfamily ------ inclusion threshold ------ 0.53 10.7 2.7 1.6 9.1 2.7 1.9 1 ENOD93 Early nodulin 93 ENOD93 protein Domain annotation for each model (and alignments): >> CLN3 CLN3 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 173.0 24.3 1.6e-54 1.4e-50 16 392 .. 57 421 .. 50 424 .. 0.90 Alignments for each domain: == domain 1 score: 173.0 bits; conditional E-value: 1.6e-54 CLN3 16 viLsAAlDlv.gksvpkgvvlladilPsllikllapffihkvpysvRvlllvllsalgmllvalskslavkllGvvlaslssGlGEvtfLqlthfy 110 v +sA +D++ g+ +p++++l + + +++ +p+f++k++y R l++v+ a+g +++ + ++++vk++Gv l +l+ GlGE++fL+l++fy FUN_001653-T1 57 VAMSASQDILaGTYIPTTTILASHVATMVIVTSSVPWFMQKISYLWRTLIVVFAMASGTIVLMTVQNVYVKIAGVSLNALAHGLGEISFLALSSFY 152 789******956778********************************************************************************* PP CLN3 111 ekeslaawssGTGgAGlvGallyalltellglsvkttlllslvlPlllllsyflllpkekleksakaeeeyealeeeeeeeeeeaeeeelleseaa 206 +k s++++++G G l+G + y+++t+++ +++++tl +++ ll ll ++++l+k++l+ a ++y++++++++e+++ FUN_001653-T1 153 GKISVTSFAAGSGVGILIGPIYYTAMTSWWCIPPQMTLAIISPAVLLALL-FYYILDKDRLKPYALLGSAYKKIKSSDSEASD------------- 234 **************************************999876555555.77788888777777666777776554433222............. PP CLN3 207 saeeeeeeeeekslkeslkeklkrlksLllkymlPLllVYlaeYliNqgvaptllfpleekpfkslrdqYrvyqvlYqlgvfisRssvsllri... 299 e+++ +++ sl+ekl+ +k++l +l L++ Y a+Y+ q+v+ t+ f +p rd Y++y ++ +g f+ Rs +s++ FUN_001653-T1 235 -----EQASGTNTYDLSLMEKLSAAKQILS-QILALCSAYAAQYITVQAVFTTIAFGD--AP-FAPRDHYVYYVLTNSVGEFMLRSYLSIVAWykp 321 .....22223345677899********965.8999*********************96..34.5789**********************9987888 PP CLN3 300 ........rklyllsvlQvlnlvllllealfelllpsiylvfllifyeGllGGaaYvntfaeiseevekeerefslgavsvsdslGillagllalp 387 ++ ++ s+l ++++++ ++++++ l ++s+++v+l+ f G l G+++ nt ++ v+++ ref++g v++++slGil+a++++l+ FUN_001653-T1 322 dliervvmKRTWIFSLLLLAIMIFSVCASYYRL-FNSVWWVILFCFSIGSLTGLVFANTVCAVPFIVDPKYREFCMGLVTIGESLGILIASFAGLA 416 8899999999*********************87.************************************************************** PP CLN3 388 lekal 392 +e+al FUN_001653-T1 417 VEPAL 421 **998 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 13.7 0.34 2.9e+03 215 319 .. 48 149 .. 32 159 .. 0.55 2 ! 11.7 0.9 1.4e-05 0.12 126 222 .. 160 275 .. 156 317 .. 0.63 3 ! 24.9 7.0 1.4e-09 1.2e-05 62 142 .. 330 415 .. 322 417 .. 0.83 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 0.34 MFS_1 215 glaffa..lltllply.qevlglsglllaglllglaallgaigrlllgrlsdrlgrrrrlllallllllaalgllllsltesslwlllallllGfg 307 +++ + ++t + + q++l + ++ + ++l+ + ++i++ + +++++++ r+l+++++++ +++ l+ + + + ++++ l ++ FUN_001653-T1 48 AIL--LhsFTTVAMSAsQDILAGT-YIPTTTILASHVATMVIVTSSVPWFMQKISYLWRTLIVVFAMASGTIVLMTVQNV---YVKIAGVSLNALA 137 222..1334444444456666666.6666666777777777777788888888777444444444444444444444444...4444455555556 PP MFS_1 308 fglvfplllalv 319 +gl +++lal FUN_001653-T1 138 HGLGEISFLALS 149 666666666554 PP == domain 2 score: 11.7 bits; conditional E-value: 1.4e-05 MFS_1 126 lsagfglGaalGpllggllaslfg..wravFlilailallaavlaalllprpppeskrkkpaee...................apapllp....aw 196 ++ag+g+G+++Gp+ ++++s++ + + +i+ + lla+++ ++++++++ ++ + + + ++ FUN_001653-T1 160 FAAGSGVGILIGPIYYTAMTSWWCipPQMTLAIISPAVLLALLF--YYILDKDRLKPYALLGSAykkikssdseasdeqasgtN-----TydlsLM 248 789*****************777699999999999999999774..55555444444444333355555555555555444441.....0333334 PP MFS_1 197 kallrdpvlw.lllalllfglaffall 222 + l + ++ +lal+++ +a ++++ FUN_001653-T1 249 EKLSAAKQILsQILALCSAYAAQYITV 275 444444444443344444433444433 PP == domain 3 score: 24.9 bits; conditional E-value: 1.4e-09 MFS_1 62 rrvlllglllfalg.lllllfa.....sslwlllvlrvlqGlgagalfpaaaaliadwfpkeergralgllsagfglGaalGpllgg 142 +r+++++lll+a++ + +++ + +s+w+++++ + G +g++f+ ++ ++ ++ ++ r + +gl+++g +lG+++++++g FUN_001653-T1 330 KRTWIFSLLLLAIMiFSVCA-SyyrlfNSVWWVILFCFSIGSLTGLVFANTVCAVPFIVDPKYREFCMGLVTIGESLGILIASFAGL 415 78999999999999666666.23345699997777777777778**************************************98885 PP >> ENOD93 Early nodulin 93 ENOD93 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 2.7 0.00019 1.6 13 59 .. 65 112 .. 54 124 .. 0.80 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00019 ENOD93 13 viaglKaAavaavvsaipTlaavr.mlpWakanlNytaqaliisaaai 59 ++ag+ + + +s ++T+++v +pW +++ y ++li+ a FUN_001653-T1 65 ILAGTYIPTTTILASHVATMVIVTsSVPWFMQKISYLWRTLIVVFAMA 112 556666666777899******997268***************987654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (453 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1163 (0.0455275); expected 510.9 (0.02) Passed bias filter: 436 (0.0170679); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4378.11 // Query: FUN_001654-T1 [L=317] Description: FUN_001654 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-66 223.3 13.4 1.2e-24 87.5 0.8 3.4 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 1.7e-59 196.2 26.0 1.4e-10 41.7 0.1 7.1 7 WD40 WD domain, G-beta repeat 9.3e-53 179.9 10.8 3.7e-33 115.5 4.0 3.4 3 Beta-prop_WDR5 WDR5 beta-propeller domain 6.4e-47 160.3 8.1 1.1e-27 97.2 0.5 4.5 3 Beta-prop_THOC3 THOC3 beta-propeller domain 7.1e-45 153.7 0.1 1.4e-34 119.9 0.1 2.7 2 WD40_Prp19 Prp19 WD40 domain 2.9e-35 122.3 3.3 2.6e-18 66.6 0.6 2.6 2 WD40_Gbeta G protein beta WD-40 repeat protei 5.5e-31 108.4 4.3 3.3e-21 76.2 2.1 3.6 2 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 7.6e-28 98.1 7.0 1.1e-09 38.6 1.0 4.5 4 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 2.5e-27 96.3 6.0 1.4e-09 38.1 0.1 5.1 4 WD40_WDHD1_1st WDHD1 first WD40 domain 7.5e-27 95.0 3.8 8.7e-12 45.4 0.0 4.5 4 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 1.3e-24 87.4 8.9 1e-07 31.8 0.9 5.3 4 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 2.3e-24 86.7 1.1 4.3e-11 43.2 0.0 4.7 4 Beta-prop_EML_2 Echinoderm microtubule-associated 3.1e-24 86.2 4.1 2e-10 40.8 0.0 3.3 3 EIF3I EIF3I 1.8e-23 83.5 12.2 1.7e-17 63.9 3.9 3.5 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 1.1e-19 71.1 0.7 1.3e-09 38.0 0.1 3.9 4 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 1.5e-18 67.4 0.0 1.4e-08 34.6 0.2 3.5 3 WDR55 WDR55 3.9e-17 62.7 5.2 2.3e-05 23.9 0.0 4.8 5 Beta-prop_SPT8 SPT8 beta propeller 1.4e-16 61.1 0.3 2.1e-06 27.6 0.0 4.1 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 3.3e-15 56.3 0.8 2.5e-07 30.4 0.1 3.3 3 Beta-prop_IFT122_1st IFT122 first beta-propeller 2.8e-14 53.2 7.1 5.3e-05 22.7 0.1 5.1 6 NBCH_WD40 Neurobeachin beta propeller domain 4.7e-14 52.7 0.7 3.3e-07 30.2 0.2 3.1 3 WDR90_beta-prop_4th WDR90, 4th beta-propeller 8.4e-14 52.1 0.0 7e-08 32.7 0.2 2.2 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 1e-13 51.9 4.2 7.1e-06 26.2 0.3 4.1 4 Beta-prop_EML Echinoderm microtubule-associated 1.6e-13 51.1 5.8 0.0012 18.8 0.1 5.6 6 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 6.2e-12 45.9 6.1 2.3e-06 27.6 0.8 4.1 4 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 2.7e-11 43.9 1.3 0.0005 20.1 0.0 4.5 5 Beta-prop_RIG_2nd RIG second beta-propeller 6.9e-11 42.6 0.5 6.4e-05 23.0 0.0 4.3 3 Beta-prop_EIPR1 EIPR1 beta-propeller 1.1e-10 41.7 6.5 0.0047 16.6 0.1 3.3 3 Beta-prop_Aladin Aladin seven-bladed propeller 2e-09 37.8 8.3 0.29 11.7 0.1 6.3 6 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 2.1e-09 37.2 3.7 0.00024 20.5 1.0 2.2 2 Beta-prop_SCAP SCAP Beta-propeller 2.6e-08 33.5 0.7 1.9e-05 24.1 0.1 2.7 2 Beta-prop_WDR75_2nd WD repeat-containing protein 75 se 5.4e-08 33.4 1.2 0.22 12.2 0.0 4.8 5 ANAPC4_WD40 Anaphase-promoting complex subunit 1.2e-07 31.5 14.5 0.025 14.0 0.6 5.2 6 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 1.7e-06 27.6 3.4 0.0068 15.7 2.3 4.2 3 Beta-prop_WDR41 WDR41 2.6e-06 27.0 0.5 0.011 15.1 0.1 3.4 4 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 5.2e-06 26.4 0.0 7.6 6.1 0.0 4.5 5 Beta-prop_HPS5 HPS5 beta-propeller 1.7e-05 24.2 4.8 0.17 11.0 0.3 3.5 3 Beta-prop_IFT140_1st IFT140 first beta-propeller 9.6e-05 22.0 1.3 1.1 8.7 0.0 3.5 4 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.00042 19.9 0.4 3.6 6.9 0.0 3.4 3 Beta-prop_VPS8 Vps8 beta-propeller 0.0022 17.7 3.1 0.31 10.6 1.6 3.3 2 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 0.0024 17.6 0.0 0.12 12.0 0.0 2.2 2 PROPPIN PROPPIN 0.0028 17.5 0.1 32 4.2 0.0 4.2 5 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 0.0034 17.3 0.1 0.93 9.3 0.1 2.3 2 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be ------ inclusion threshold ------ 0.052 12.6 0.1 0.39 9.7 0.3 2.0 2 Cytochrom_D1 Cytochrome D1 heme domain 0.12 12.1 0.0 1.2 8.8 0.0 2.2 2 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller 0.15 12.4 0.0 0.26 11.7 0.0 1.3 1 DUF1416 Protein of unknown function (DUF14 0.19 12.2 0.9 47 4.6 0.0 4.5 4 PD40 WD40-like Beta Propeller Repeat 0.21 11.0 1.2 0.78 9.2 0.5 2.2 2 Beta-prop_pof12 F-box protein pof12 beta-propeller Domain annotation for each model (and alignments): >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.5 0.8 2.3e-27 1.2e-24 64 183 .. 8 133 .. 3 134 .. 0.91 2 ! 81.7 3.1 1.4e-25 7.3e-23 25 149 .. 59 186 .. 58 191 .. 0.89 3 ! 74.5 0.0 2.2e-23 1.2e-20 25 184 .] 144 312 .. 134 312 .. 0.86 Alignments for each domain: == domain 1 score: 87.5 bits; conditional E-value: 2.3e-27 Beta-prop_WDR3_1st 64 evtfngHksavtalafdkdg.srLasGskDtdiivwDvvaeaglf.....rLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcv 148 + t++gH + vt +a ++++ ++ sGs+D+++ivw++++++ + L gH++ v +v++++++++ +s+S D +++lWdl+ + FUN_001654-T1 8 RGTLKGHDGWVTQIATNPQDpDKILSGSRDKKLIVWNLTRDETNYgvayrALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTT 98 669*************9865389***************98876543334379*************************************** PP Beta-prop_WDR3_1st 149 ktlvghrsevwslalskdekllvtgssdselrvwk 183 + +vgh++ v s+a+s+d++ +v+gs+d+++++w+ FUN_001654-T1 99 RRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWN 133 **********************************7 PP == domain 2 score: 81.7 bits; conditional E-value: 1.4e-25 Beta-prop_WDR3_1st 25 legeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeag.lfrLkgHkd 114 l+g+++ v+ + +s+dg+ +G+ d ++rlwdl+ g ++ f gH++ v ++af++d+ +++sGs+D++i +w+++ ++ +++ +gH+d FUN_001654-T1 59 LTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKyTIQDEGHSD 149 68999**********************************************************************998765145667**** PP Beta-prop_WDR3_1st 115 qvtsvaflee..kkvlvssSkDtliklWdletqhcvk 149 v v+f+++ + ++vs++ D+l+k+W+l++ + + FUN_001654-T1 150 WVSCVRFSPNssNPIIVSAGWDKLVKVWNLTNCRLKT 186 ********8622569***************9866555 PP == domain 3 score: 74.5 bits; conditional E-value: 2.2e-23 Beta-prop_WDR3_1st 25 legeksevtalaaspdgk..klavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHk 113 eg+++ v+++++sp+++ + ++ d+ +++w+l++ +l+++ gH++ ++++ ++dgs asG+kD ++wD+ +++ l++L+g FUN_001654-T1 144 DEGHSDWVSCVRFSPNSSnpIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGG- 233 368999********9875336777788**************************************************************5. PP Beta-prop_WDR3_1st 114 dqvtsvafleekkvlvssSkDtliklWdletqhcvktlvgh.........rsevwslalskdekllvtgssdselrvwki 184 d ++s++f++++ +l ++ +ik+Wdle ++ v l+ ++ ++sla s+d+++l++g +d+ +rvw++ FUN_001654-T1 234 DIINSLCFSPNRYWLC-AAVGPTIKIWDLEGKSLVDELTLDvismggkppSADCMSLAWSADGQTLFAGYTDNLIRVWHV 312 89********987765.667789**********999886432222222337899************************86 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 0.0 1e-08 5.3e-06 3 39 .] 7 44 .. 5 44 .. 0.92 2 ! 34.8 0.6 3.9e-11 2.1e-08 5 39 .] 57 91 .. 53 91 .. 0.92 3 ! 41.7 0.1 2.7e-13 1.4e-10 3 39 .] 97 133 .. 95 133 .. 0.93 4 ! 35.5 0.9 2.4e-11 1.3e-08 3 39 .] 138 178 .. 136 178 .. 0.88 5 ! 27.2 0.1 1e-08 5.4e-06 7 39 .] 188 220 .. 182 220 .. 0.89 6 ! 23.2 0.1 1.9e-07 0.0001 1 39 [] 224 260 .. 224 260 .. 0.89 7 ! 21.4 0.1 7e-07 0.00037 13 38 .. 285 310 .. 276 311 .. 0.90 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 1e-08 WD40 3 llrtlkgHtsgVtsla.fspdgsllasgsdDgtvklWd 39 l +tlkgH+++Vt +a ++d + ++sgs+D+++ +W+ FUN_001654-T1 7 LRGTLKGHDGWVTQIAtNPQDPDKILSGSRDKKLIVWN 44 5789****999*****99999999*************7 PP == domain 2 score: 34.8 bits; conditional E-value: 3.9e-11 WD40 5 rtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 r l+gH+ V+++ s+dg++ +sgs+D t++lWd FUN_001654-T1 57 RALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWD 91 6799**888*************************9 PP == domain 3 score: 41.7 bits; conditional E-value: 2.7e-13 WD40 3 llrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +r + gHt++V s+afs d++ ++sgs+D+++klW+ FUN_001654-T1 97 TTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWN 133 567899******************************7 PP == domain 4 score: 35.5 bits; conditional E-value: 2.4e-11 WD40 3 llrtl..kgHtsgVtslafspdgsl..lasgsdDgtvklWd 39 + +t+ +gH+++V++++fsp++s ++s+++D+ vk+W+ FUN_001654-T1 138 CKYTIqdEGHSDWVSCVRFSPNSSNpiIVSAGWDKLVKVWN 178 66676446**999*************999***********7 PP == domain 5 score: 27.2 bits; conditional E-value: 1e-08 WD40 7 lkgHtsgVtslafspdgsllasgsdDgtvklWd 39 gH++ + ++ spdgsl asg++Dg +lWd FUN_001654-T1 188 HIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWD 220 459*888999999*******************9 PP == domain 6 score: 23.2 bits; conditional E-value: 1.9e-07 WD40 1 gkllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 gk l+tl+g + ++sl+fsp+ +l++ + t+k+Wd FUN_001654-T1 224 GKHLYTLEGG-DIINSLCFSPNRYWLCA-AVGPTIKIWD 260 67899**999.77*************75.55*******9 PP == domain 7 score: 21.4 bits; conditional E-value: 7e-07 WD40 13 gVtslafspdgsllasgsdDgtvklW 38 + +sla+s dg+ l++g D+ +++W FUN_001654-T1 285 DCMSLAWSADGQTLFAGYTDNLIRVW 310 5789*************99******* PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 115.5 4.0 7e-36 3.7e-33 1 165 [. 10 183 .. 10 186 .. 0.90 2 ! 72.6 0.1 8.5e-23 4.5e-20 87 208 .. 145 265 .. 138 273 .. 0.91 3 ! 9.3 0.0 0.0017 0.89 53 78 .. 288 313 .. 276 316 .. 0.78 Alignments for each domain: == domain 1 score: 115.5 bits; conditional E-value: 7e-36 Beta-prop_WDR5 1 tlkghkkavssvkfsp.dgkllasasaDktikiwdv.....eegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgH 89 tlkgh v+++ +p d + + s s Dk + +w++ + g + l+gh++ +sdv ssd+++ s+S D t+r+wd++ g +++ + gH FUN_001654-T1 10 TLKGHDGWVTQIATNPqDPDKILSGSRDKKLIVWNLtrdetNYGVAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGH 104 6899********999845799**************844333335599************************************************ PP Beta-prop_WDR5 90 tnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktl..paHsdpvsavdfnrdgt..livsssyDgliriwdtetgq 165 t+ v++vaF++++ +vSGs D++++lW++ g c t+ ++Hsd vs+v+f+ +++ +ivs+ D l+++w+ ++++ FUN_001654-T1 105 TKDVLSVAFSADNRQIVSGSRDKSIKLWNTL-GVCKYTIqdEGHSDWVSCVRFSPNSSnpIIVSAGWDKLVKVWNLTNCR 183 ****************************975.78888884458**********99988779**************98865 PP == domain 2 score: 72.6 bits; conditional E-value: 8.5e-23 Beta-prop_WDR5 87 kgHtnyvfcvaFnpkgn..llvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliriwdtetgqclktlveddnppvs 179 +gH+++v cv+F+p+++ ++vS++ D+ v++W++++ ++ +H+ v + dg+l +s+ Dg+ +wd ++g+ l tl + FUN_001654-T1 145 EGHSDWVSCVRFSPNSSnpIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLE--GGDIIN 237 79**********99864348******************************************************************5..7889** PP Beta-prop_WDR5 180 fvkFspngkyiLastldstirLwdyekek 208 + Fspn +y L++++ ti++wd+e + FUN_001654-T1 238 SLCFSPN-RYWLCAAVGPTIKIWDLEGKS 265 ******9.79999***********98665 PP == domain 3 score: 9.3 bits; conditional E-value: 0.0017 Beta-prop_WDR5 53 dvawssdskllasaSDDktvriwdve 78 ++aws+d+++l ++ D+ +r+w+v+ FUN_001654-T1 288 SLAWSADGQTLFAGYTDNLIRVWHVT 313 57888888888888888888888775 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.4 0.4 5.4e-14 2.9e-11 41 122 .. 10 97 .. 2 101 .. 0.76 2 ! 97.2 0.5 2.1e-30 1.1e-27 1 166 [. 104 269 .. 104 277 .. 0.87 3 ! 18.6 0.1 1.9e-06 0.001 4 32 .. 285 313 .. 282 316 .. 0.89 Alignments for each domain: == domain 1 score: 43.4 bits; conditional E-value: 5.4e-14 Beta-prop_THOC3 41 elkghtdsVeqlawspthpdllatassDktvrlWdvrt.....gkstatvktkgenin.lawspdGktiavgskddtvslidvrtgkv 122 +lkgh+++V+q+a +p++pd + ++s+Dk++ +W++ g + + ++++++ ++ + s dG++ ++gs d t++l+d++ g + FUN_001654-T1 10 TLKGHDGWVTQIATNPQDPDKILSGSRDKKLIVWNLTRdetnyGVAYRALTGHNHFVSdVVMSSDGQFALSGSWDATLRLWDLNAGVT 97 7899999999999999999999999999999999976522222335666777777665599999999999999999999999987755 PP == domain 2 score: 97.2 bits; conditional E-value: 2.1e-30 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpd.llatassDktvrlWdvrtgkstatvktkgenin 93 h+k v sva+sad ++++sgs Dk++++wn+ ++ + + +gh+d+V+++++sp++++ ++++a++Dk v++W++ + + ++ +++ ++n FUN_001654-T1 104 HTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGV-CKYTIQDEGHSDWVSCVRFSPNSSNpIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLN 196 999***************************9855.5667889**************98875889**************9776555555555665 PP Beta-prop_THOC3 94 .lawspdGktiavgskddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgdgtvevlsypsleevkt 166 ++ spdG+ +a+g kd + l+d+++gk + + + +n+++fsp+ l+ ++ t+++++++ v + FUN_001654-T1 197 vVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGGDIINSLCFSPNRYWLC-AAVGPTIKIWDLEGKSLVDE 269 499********************************************877776.55667999999876555555 PP == domain 3 score: 18.6 bits; conditional E-value: 1.9e-06 Beta-prop_THOC3 4 kvhsvawsadGkrLasgsaDktvrvwnle 32 + s+awsadG++L +g +D+ +rvw++ FUN_001654-T1 285 DCMSLAWSADGQTLFAGYTDNLIRVWHVT 313 5679**********************986 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.0 1e-12 5.4e-10 43 127 .. 9 99 .. 3 102 .. 0.86 2 ! 119.9 0.1 2.6e-37 1.4e-34 18 247 .. 74 312 .. 72 316 .. 0.88 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 1e-12 WD40_Prp19 43 atlkghtkkvtavafhpse.dvlvsasaDktvrvwkkeeketaa.....tlkkhkaevtslsvhptgdylvsaskDgtwalhdletgktll 127 tlkgh vt++a +p++ d ++s+s Dk+ vw+ + +et++ +l+ h++ v+++ + g++++s+s D+t+ l+dl++g t + FUN_001654-T1 9 GTLKGHDGWVTQIATNPQDpDKILSGSRDKKLIVWNLTRDETNYgvayrALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTR 99 689************9987579**************98886654333336999********************************998765 PP == domain 2 score: 119.9 bits; conditional E-value: 2.6e-37 WD40_Prp19 18 dknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkk..hkaevtslsvhp..tgdylvsa 109 d + l+G D+++ l+d +++ +++++ ghtk v +vaf+ +++ +vs+s Dk++++w++ +++t+++ h++ v+++ + p ++ +vsa FUN_001654-T1 74 DGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLG-VCKYTIQDegHSDWVSCVRFSPnsSNPIIVSA 168 67889******************************************************9966.56666554349**9***999993356799*** PP WD40_Prp19 110 skDgtwalhdletgktllkvkdeeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsasedgtvklWD 205 + D+ +++++l++++ ++ ++ ++ + + PDG+l++ G kdg+ +WD++++k + +leg + ++sl+FS N Y L +a t+k+WD FUN_001654-T1 169 GWDKLVKVWNLTNCRLKTNHIG--HQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGG-DIINSLCFSPNRYWLCAAVGP-TIKIWD 260 ************9998665544..4457899**********************************86.58***************9998.****** PP WD40_Prp19 206 LRklknfktleld........eeskvnsvaFDksgqyLavagsd..vrvyev 247 L ++ + +l+ld ++ + s+a+ gq L ++ +d +rv++v FUN_001654-T1 261 LEGKSLVDELTLDvismggkpPSADCMSLAWSADGQTLFAGYTDnlIRVWHV 312 ************866666544457899***********99976656899887 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.6 0.6 4.8e-21 2.6e-18 98 238 .. 16 160 .. 6 161 .. 0.89 2 ! 61.8 0.5 1.4e-19 7.5e-17 139 299 .. 144 312 .. 136 316 .. 0.84 Alignments for each domain: == domain 1 score: 66.6 bits; conditional E-value: 4.8e-21 WD40_Gbeta 98 swvmtcayapsg.nfvacggldnicsiynlktregnvrvs.relaghtgylsccrflddnqiv.tssgdttcalwdietgqqttvfvghtgdvmsl 190 wv a p + + g d+ ++nl e n v+ r l+gh ++s + + d q + s d+t lwd+++g t fvght dv+s+ FUN_001654-T1 16 GWVTQIATNPQDpDKILSGSRDKKLIVWNLTRDETNYGVAyRALTGHNHFVSDVVMSSDGQFAlSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSV 111 699999988875367889999***************9996599***********99999997515689**************************** PP WD40_Gbeta 191 slapdtrlfvsgacdasaklwdvreglcrqtfi..ghesdinaiaffpng 238 +++ d r +vsg+ d s+klw+ g+c+ t+ gh + ++ f pn FUN_001654-T1 112 AFSADNRQIVSGSRDKSIKLWNT-LGVCKYTIQdeGHSDWVSCVRFSPNS 160 *********************97.589***98544899999999999996 PP == domain 2 score: 61.8 bits; conditional E-value: 1.4e-19 WD40_Gbeta 139 laghtgylsccrfl..ddnqivtssg.dttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdina 231 gh+ ++sc+rf n i+ s+g d + +w++ + +t +gh g + ++++pd+ l sg d a lwd+ eg t+ g + in+ FUN_001654-T1 144 DEGHSDWVSCVRFSpnSSNPIIVSAGwDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGGD-IINS 238 579**********732468899998868999***************************************************999999976.59** PP WD40_Gbeta 232 iaffpngealatgsddatcrlfdlradqellvyshdniicg.......itsvafsksgrlllagyddfncnvwda 299 ++f pn + l++ t +++dl + + d i g s+a+s g+ l+agy d vw FUN_001654-T1 239 LCFSPNRYWLCAAV-GPTIKIWDLEGKSLVDELTLDVISMGgkppsadCMSLAWSADGQTLFAGYTDNLIRVWHV 312 **********9876.5799*****987655555666665442333222789**********************75 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.2 2.1 6.3e-24 3.3e-21 75 287 .. 10 220 .. 5 225 .. 0.88 2 ! 39.7 0.0 8.3e-13 4.4e-10 133 289 .. 148 313 .. 147 315 .. 0.82 Alignments for each domain: == domain 1 score: 76.2 bits; conditional E-value: 6.3e-24 Beta-prop_WDR3_2nd 75 tieahegavwsvaltp.dekglvtggaDkkvkfwefelveeeeskakklslkhtrtlk.lsddvlcvkvspdkkllavallDstvkvfflD 163 t++ h+g v ++a++p d ++++g+ Dkk+ +w+++ e++ + + r+l ++ v v +s+d+++ + D+t +++ l+ FUN_001654-T1 10 TLKGHDGWVTQIATNPqDPDKILSGSRDKKLIVWNLTRDETNY------GV-AYRALTgHNHFVSDVVMSSDGQFALSGSWDATLRLWDLN 93 6789********999857899**************97655432......22.33444413445667899********************** PP Beta-prop_WDR3_2nd 164 tlkfflslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchksl..fahddsvmsvafvpkt..HylfsagkdkkvkyWDadkfe 250 + + Gh+ vls+ +s D++ iv+gs Dk+ik+w + G c+ ++ +h+d v v+f p++ + sag dk vk W+ + FUN_001654-T1 94 AGVTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT-LGVCKYTIqdEGHSDWVSCVRFSPNSsnPIIVSAGWDKLVKVWNLTNCR 183 ***************************************85.8*******6669************98334699***************** PP Beta-prop_WDR3_2nd 251 kiqtleghagevwalavsskgkfvvsashDksiRlwe 287 ++ gh+g + ++vs +g++ +s+++D + lw+ FUN_001654-T1 184 LKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWD 220 *******************************999997 PP == domain 2 score: 39.7 bits; conditional E-value: 8.3e-13 Beta-prop_WDR3_2nd 133 sddvlcvkvspdk..kllavallDstvkvfflDtlkfflslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchkslfahddsvm 221 sd v cv++sp++ +++ a D+ vkv+ l +++ + Gh+ + + +s D++l+++g +D +w l+ G +l + d + FUN_001654-T1 148 SDWVSCVRFSPNSsnPIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEG-GDIIN 237 57799*****986215777789*******************************************************87777776.899** PP Beta-prop_WDR3_2nd 222 svafvpktHylfsagkdkkvkyWDadkfekiqtl.......egh..agevwalavsskgkfvvsashDksiRlwert 289 s+ f p+ + + a+ ++k WD + + + +l g+ ++++++la s +g+ + ++ +D+ iR+w+ t FUN_001654-T1 238 SLCFSPNRYW-LCAAVGPTIKIWDLEGKSLVDELtldvismGGKppSADCMSLAWSADGQTLFAGYTDNLIRVWHVT 313 *****98755.5677789******76555444331111111554336889999*********************987 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.1 3.2e-08 1.7e-05 88 165 .. 10 93 .. 2 98 .. 0.82 2 ! 38.6 1.0 2e-12 1.1e-09 128 214 .. 98 184 .. 93 193 .. 0.87 3 ! 23.8 0.0 6.2e-08 3.3e-05 133 218 .. 190 270 .. 182 276 .. 0.85 4 ! 11.6 0.0 0.00033 0.17 139 164 .. 287 312 .. 280 316 .. 0.70 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 3.2e-08 WD40_CDC20-Fz 88 tleghssrvgalawnenl...lssGsrdgkilhhDvrtkelev...vktlkahkqevcglkwspdgrllAsGgndntvkiwdlr 165 tl+gh+ v+++a n + ++sGsrd+k++++++ e + + l++h++ v+ + +s+dg++ sG+ d t+++wdl+ FUN_001654-T1 10 TLKGHDGWVTQIATNPQDpdkILSGSRDKKLIVWNLTRDETNYgvaYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLN 93 678899999999997654445**********9999876654431225689********************************86 PP == domain 2 score: 38.6 bits; conditional E-value: 2e-12 WD40_CDC20-Fz 128 vktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslsp.llkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkl 214 ++++ +h+++v ++++s+d+r++ sG+ d+++k+w++ + + + + + h+ v ++ ++p++++ ++ G Dk +++wn +++ l FUN_001654-T1 98 TRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKyTIQDEGHSDWVSCVRFSPNSSNPIIVSAGW-DKLVKVWNLTNCRL 184 57899*******************************9977551667889****************88888886.********998765 PP == domain 3 score: 23.8 bits; conditional E-value: 6.2e-08 WD40_CDC20-Fz 133 ahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksv 218 +h++ +++spdg+l AsGg+d++ ++wdl++ + l++l+ + l ++p++ l a G ti++w+ + ++l++++ FUN_001654-T1 190 GHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLE-GGDIINSLCFSPNRYWLCAAVG----PTIKIWDLEGKSLVDEL 270 6888888899****************************9996.6889********8766666655....58*****9999998876 PP == domain 4 score: 11.6 bits; conditional E-value: 0.00033 WD40_CDC20-Fz 139 cglkwspdgrllAsGgndntvkiwdl 164 +l+ws+dg++l G dn++++w++ FUN_001654-T1 287 MSLAWSADGQTLFAGYTDNLIRVWHV 312 46777777777777777777777765 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.0 0.0012 0.66 123 162 .. 10 50 .. 3 55 .. 0.90 2 ! 38.1 0.1 2.6e-12 1.4e-09 88 157 .. 65 134 .. 53 136 .. 0.94 3 ! 14.0 0.2 5.8e-05 0.031 125 161 .. 145 183 .. 137 192 .. 0.80 4 ! 31.9 0.0 2e-10 1.1e-07 89 204 .. 195 309 .. 190 313 .. 0.81 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0012 WD40_WDHD1_1st 123 tleghkapvlsvaldpkg.eylaSsscDGtvkiWdieskec 162 tl+gh++ v+ +a +p++ + S s D ++ +W+++ +e+ FUN_001654-T1 10 TLKGHDGWVTQIATNPQDpDKILSGSRDKKLIVWNLTRDET 50 79***************97899*************998765 PP == domain 2 score: 38.1 bits; conditional E-value: 2.6e-12 WD40_WDHD1_1st 88 pvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdi 157 v ++ +s dg++ +gs D t+++ +++ + ++ + gh++ vlsva+++ + ++S s D ++k+W+ FUN_001654-T1 65 FVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT 134 588999**************************************************************95 PP == domain 3 score: 14.0 bits; conditional E-value: 5.8e-05 WD40_WDHD1_1st 125 eghkapvlsvaldpkg..eylaSsscDGtvkiWdieske 161 egh++ v +v+++p++ +++S++ D vk+W++++ + FUN_001654-T1 145 EGHSDWVSCVRFSPNSsnPIIVSAGWDKLVKVWNLTNCR 183 799999999999998733689999999999999998765 PP == domain 4 score: 31.9 bits; conditional E-value: 2e-10 WD40_WDHD1_1st 89 vthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlk..vlpksndfsasksl 181 + +++s+dg+l+a+g++D + + +++++++ tleg + + s++++p++ y +++ t+kiWd+e k+ v +l+ v+++ + s + FUN_001654-T1 195 LNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGG-DIINSLCFSPNR-YWLCAAVGPTIKIWDLEGKSLVDELTldVISMGGKPP-SADC 286 57799***************************99**995.68********99.667788899***********99877532777777765.5688 PP WD40_WDHD1_1st 182 crlawepksgkllavP.vekevkl 204 + law+ + g++l+ +++ +++ FUN_001654-T1 287 MSLAWSAD-GQTLFAGyTDNLIRV 309 99***987.666655414444555 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.16 85 154 189 .. 12 48 .. 6 56 .. 0.63 2 ! 22.5 0.1 1.6e-07 8.3e-05 233 272 .. 56 95 .. 49 98 .. 0.93 3 ! 22.5 0.2 1.5e-07 8e-05 233 269 .. 98 134 .. 95 160 .. 0.87 4 ! 45.4 0.0 1.6e-14 8.7e-12 153 304 .. 144 306 .. 136 312 .. 0.85 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.16 Beta-prop_WDR36-Utp21_2nd 154 kahkkavrGvavdaln.qvvitagadkklkfwkfksk 189 k h++ v+ +a++ +++++++dkkl +w++ + FUN_001654-T1 12 KGHDGWVTQIATNPQDpDKILSGSRDKKLIVWNLTRD 48 5666666666666443256777777777777776654 PP == domain 2 score: 22.5 bits; conditional E-value: 1.6e-07 Beta-prop_WDR36-Utp21_2nd 233 vRkfsghknritDltfspdarWlitasmDstirtwdlpsg 272 R ++gh+ ++D+++s d+++ ++ s D+t+r wdl++g FUN_001654-T1 56 YRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAG 95 599**********************************987 PP == domain 3 score: 22.5 bits; conditional E-value: 1.5e-07 Beta-prop_WDR36-Utp21_2nd 233 vRkfsghknritDltfspdarWlitasmDstirtwdl 269 R+f gh+ + ++fs+d r +++ s D +i+ w+ FUN_001654-T1 98 TRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT 134 69*********************************85 PP == domain 4 score: 45.4 bits; conditional E-value: 1.6e-14 Beta-prop_WDR36-Utp21_2nd 153 ekahkkavrGvav..dalnqvvitagadkklkfwkfkskkllet.lkleasisklvlhressllavalddfsilvvDidtrrvv 233 ++ h++ v+ v ++ n ++++ag dk +k+w++ +++l+++ + + + +++ + sl a d + ++ D++ + FUN_001654-T1 144 DEGHSDWVSCVRFspNSSNPIIVSAGWDKLVKVWNLTNCRLKTNhIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHL 227 567777777776522578999*****************99986615666678888999************************** PP Beta-prop_WDR36-Utp21_2nd 234 RkfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvflve..........saatslslsptgdfLatahvddl 304 +++g i+ l+fsp+ Wl a++ ti++wdl +l+D ++++ ++sl+ s+ g+ L + ++d+l FUN_001654-T1 228 YTLEGG-DIINSLCFSPNRYWLC-AAVGPTIKIWDLEGKSLVDELTLDvismggkppsADCMSLAWSADGQTLFAGYTDNL 306 ***995.68************97.56899***************9998777888777677999999999999999888886 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.4 1.8e-08 9.7e-06 121 201 .. 6 92 .. 1 93 [. 0.83 2 ! 31.8 0.9 1.9e-10 1e-07 123 208 .. 98 186 .. 94 189 .. 0.87 3 ! 21.7 0.0 2.3e-07 0.00012 36 103 .. 165 225 .. 159 238 .. 0.85 4 ! 11.3 0.0 0.00031 0.16 132 161 .. 285 314 .. 280 316 .. 0.92 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 1.8e-08 Beta-prop_CAF1B_HIR1 121 lvlkvlrGhledvyDlswsp.dskklisgsvDntailWdvekgkk.....lailkdhkgfvqgvawdPknqyvatlssDrslrifdi 201 + +l+Gh v ++ p d k++sgs D + i+W++++ ++ l+ h++fv v + +q+ + s D +lr++d+ FUN_001654-T1 6 TLRGTLKGHDGWVTQIATNPqDPDKILSGSRDKKLIVWNLTRDETnygvaYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDL 92 556689**********988626689**************9986541111157899****************************9986 PP == domain 2 score: 31.8 bits; conditional E-value: 1.9e-10 Beta-prop_CAF1B_HIR1 123 lkvlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkd.hkgfvqgvawdPk..nqyvatlssDrslrifdiktkkvva 208 ++ + Gh++dv +++s+d+++++sgs D ++ lW+ k +i ++ h ++v v + P+ n +++++ D+ ++++++++ ++ + FUN_001654-T1 98 TRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIQDEgHSDWVSCVRFSPNssNPIIVSAGWDKLVKVWNLTNCRLKT 186 66788*******************************9988888887664899*********733678999999*******999887765 PP == domain 3 score: 21.7 bits; conditional E-value: 2.3e-07 Beta-prop_CAF1B_HIR1 36 lasgGaDshvliWkvkieeegkvklelladltrhqkavnvvrfspsgelLasgdDesviiiWklkeee 103 + s+G D+ v++W+++ l ++ hq nvv sp+g+l asg+ +++ ++W l+e + FUN_001654-T1 165 IVSAGWDKLVKVWNLTNC-------RLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGK 225 689***********9875.......44556668******************************99876 PP == domain 4 score: 11.3 bits; conditional E-value: 0.00031 Beta-prop_CAF1B_HIR1 132 dvyDlswspdskklisgsvDntailWdvek 161 d + l+ws+d+++l +g Dn + +W+v++ FUN_001654-T1 285 DCMSLAWSADGQTLFAGYTDNLIRVWHVTR 314 8889***********************987 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 1.8e-05 0.0094 78 156 .. 12 95 .. 4 99 .. 0.82 2 ! 17.2 0.1 6.9e-06 0.0037 228 265 .. 97 133 .. 93 134 .. 0.90 3 ? 3.2 0.0 0.13 67 233 249 .. 145 161 .. 138 162 .. 0.75 4 ! 43.2 0.0 8.1e-14 4.3e-11 8 154 .. 160 313 .. 157 315 .. 0.81 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.8e-05 Beta-prop_EML_2 78 kdrkeaisdikfsp.dgklLavgshdnkiylYdvsk...kyk.kvgklkghssfithlDwsedskylqsnsgdyellfwdaktg 156 k ++ ++++i+ +p d + + gs+d+k+ ++++++ +y ++ l+gh++f+ + s+d+++ s s d l +wd++ g FUN_001654-T1 12 KGHDGWVTQIATNPqDPDKILSGSRDKKLIVWNLTRdetNYGvAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAG 95 6667789999999845578888************87333343266779********************************9887 PP == domain 2 score: 17.2 bits; conditional E-value: 6.9e-06 Beta-prop_EML_2 228 kykkykgHsshVtnvrFladdsylistGGaDasvfqWk 265 + +++ gH++ V +v+F+ad+++++s G +D+s+ W+ FUN_001654-T1 97 TTRRFVGHTKDVLSVAFSADNRQIVS-GSRDKSIKLWN 133 568899***************99998.9******9997 PP == domain 3 score: 3.2 bits; conditional E-value: 0.13 Beta-prop_EML_2 233 kgHsshVtnvrFladds 249 +gHs V +vrF++++s FUN_001654-T1 145 EGHSDWVSCVRFSPNSS 161 68888888888888765 PP == domain 4 score: 43.2 bits; conditional E-value: 8.1e-14 Beta-prop_EML_2 8 psepqfvTagdDktvrlWdlekkklva.kvklekearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgs 100 s+p++v+ag Dk v +W+l + +l ++ + ++ v++spdg+l+a G kdG +++d ++++++++++ + i+ + fsp+ +L+++ FUN_001654-T1 160 SSNPIIVSAGWDKLVKVWNLTNCRLKTnHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLE-GGDIINSLCFSPNRYWLCAAV 252 57899***************8877655156777789*********************************986.5689*************9887 PP Beta-prop_EML_2 101 hdnkiylYdvskk.......ykkvgklkg.hssfithlDwsedskylqsnsgdyellfwdak 154 +i+++d++ k ++ +++ + s ++l ws+d+++l +d+ + +w+++ FUN_001654-T1 253 -GPTIKIWDLEGKslvdeltLDVISMGGKpPSADCMSLAWSADGQTLFAGYTDNLIRVWHVT 313 .678*****986433322223333333221467799***********999999999999876 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.3 0.4 1.4e-10 7.5e-08 6 87 .. 11 98 .. 8 102 .. 0.86 2 ! 30.4 0.9 5.5e-10 2.9e-07 6 92 .. 59 144 .. 58 161 .. 0.85 3 ! 40.8 0.0 3.7e-13 2e-10 7 176 .. 145 313 .. 140 316 .. 0.82 Alignments for each domain: == domain 1 score: 32.3 bits; conditional E-value: 1.4e-10 EIF3I 6 lkGheRaltqikyn.reGDllfsvakdkkasvwysen.....GerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkel 87 lkGh+ +tqi n ++ D ++s ++dkk vw + G +++Gh+ v ++ ++s+ + +++gs d t++lWd++ G + FUN_001654-T1 11 LKGHDGWVTQIATNpQDPDKILSGSRDKKLIVWNLTRdetnyGVAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTT 98 9***********996689***************86541111144566899*********************************99875 PP == domain 2 score: 30.4 bits; conditional E-value: 5.5e-10 EIF3I 6 lkGheRaltqikynreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktlet 92 l+Gh+ ++ + ++++G + +s + d + +w + G + Gh+ v s+ + + +++v+gs d+++klW++ G + t++ FUN_001654-T1 59 LTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT-LGVCKYTIQD 144 89************************************************************************97.5666555543 PP == domain 3 score: 40.8 bits; conditional E-value: 3.7e-13 EIF3I 7 kGheRaltqiky..nreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletktavrsve 100 +Gh+ ++ +++ n+ +++s++ dk + vw +n + Gh+G + + v+ + +l+++g d ++ lWd+++Gk+l tle + s FUN_001654-T1 145 EGHSDWVSCVRFspNSSNPIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGGDIINSLC 240 6899999999995566778******************86666688*************************************************** PP EIF3I 101 fsesgkllllvtdkvmgkkseivvldirdeeeeee.eepvlki..eveeskvtvalwsaldktiitghedgeiskydlk 176 fs++ l++ + +i++ d++ ++ ++e + v+++ + ++ +++ +wsa ++t+ +g +d i ++++ FUN_001654-T1 241 FSPNRYWLCAAVG------PTIKIWDLEGKSLVDElTLDVISMggKPPSADCMSLAWSADGQTLFAGYTDNLIRVWHVT 313 ***9888876654......567777877665444313333333114556788999999999999999999999999865 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.9 3.9 3.2e-20 1.7e-17 82 253 .. 7 178 .. 1 180 [. 0.83 2 ! 17.0 0.1 6.7e-06 0.0036 85 123 .. 187 225 .. 179 271 .. 0.76 3 ? 5.8 0.1 0.017 9.1 2 28 .. 287 314 .. 286 317 .] 0.84 Alignments for each domain: == domain 1 score: 63.9 bits; conditional E-value: 3.2e-20 Beta-prop_TEP1_2nd 82 slsvlrghtgavtccsfsl.dGgllatggrdrsllcWdvrvpkaP.vlirsllachrdWvtgcaWtkd.dllvscssdGsvglWdiekeqr 169 +l+gh+g vt + ++ d +++ +g+rd++l++W++ ++ +++ l+ h+ +v+ +d ++ +s+s d +++lWd++++ FUN_001654-T1 7 LRGTLKGHDGWVTQIATNPqDPDKILSGSRDKKLIVWNLTRDETNyGVAYRALTGHNHFVSDVVMSSDgQFALSGSWDATLRLWDLNAGVT 97 56689********99988636788**************98775541577888899******99988773678******************* PP Beta-prop_TEP1_2nd 170 lgkflGhqsavsavv..aveehvvsvgrdGllkvWdlqGveltsikahsgqisqcaaalePreagqagsellvvtaGldgavklWs 253 +f+Gh v +v+ a + ++vs +rd ++k W+ Gv +i+ + ++ P++ s+ ++v+aG d vk+W+ FUN_001654-T1 98 TRRFVGHTKDVLSVAfsADNRQIVSGSRDKSIKLWNTLGVCKYTIQDEGHSDWVSCVRFSPNS-----SNPIIVSAGWDKLVKVWN 178 ***********99873256678******************99999876444333444556777.....478999***********6 PP == domain 2 score: 17.0 bits; conditional E-value: 6.7e-06 Beta-prop_TEP1_2nd 85 vlrghtgavtccsfsldGgllatggrdrsllcWdvrvpk 123 gh+g ++ + s+dG+l a+gg+d ++Wd+++ k FUN_001654-T1 187 NHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGK 225 5579******************************98855 PP == domain 3 score: 5.8 bits; conditional E-value: 0.017 Beta-prop_TEP1_2nd 2 salvWlsd.kvlvsGaedgslqvWklee 28 ++l+W d ++l +G d +++vW++++ FUN_001654-T1 287 MSLAWSADgQTLFAGYTDNLIRVWHVTR 314 68999876489*************9986 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.1 7.6e-11 4e-08 238 340 .. 29 133 .. 18 134 .. 0.92 2 ! 38.0 0.1 2.5e-12 1.3e-09 94 206 .. 69 178 .. 62 188 .. 0.90 3 ! 11.5 0.0 0.00028 0.15 90 130 .. 194 234 .. 177 245 .. 0.83 4 ? -0.8 0.0 1.5 8.2e+02 24 37 .. 299 312 .. 285 315 .. 0.50 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 7.6e-11 WD40_MABP1-WDR62_2nd 238 klvavacqDrnirvynvssgkqk..ksfkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGecvatvfGhseivtglkFtedc 324 ++++ +++D+++ v+n++ +++ ++++ ++++ + v + + g+++ + + d +l ++d+++G ++ +Gh+ v ++ F++d FUN_001654-T1 29 DKILSGSRDKKLIVWNLTRDETNygVAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADN 117 5688899**********87766522689************************************************************* PP WD40_MABP1-WDR62_2nd 325 rhlisvsgDsCifvWr 340 r+++s s D i +W+ FUN_001654-T1 118 RQIVSGSRDKSIKLWN 133 ***************6 PP == domain 2 score: 38.0 bits; conditional E-value: 2.5e-12 WD40_MABP1-WDR62_2nd 94 lkvspdgkhlasGDrsGniriydletleellkieahdsevlcleyskpetglkllasasRDRlihvfdvekdysllqtlddhsssitav 182 + +s dg+ sG ++r++dl+ + ++ h +vl++ +s + + ++s+sRD+ i++++ ++ + + hs +++v FUN_001654-T1 69 VVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADN---RQIVSGSRDKSIKLWNTLGVCKYTIQDEGHSDWVSCV 154 7799*****************************************9875...5589************9999888888888******** PP WD40_MABP1-WDR62_2nd 183 kfaeeeeklkliscgaDksilfrk 206 +f+ ++++ ++s+g Dk + + + FUN_001654-T1 155 RFSPNSSNPIIVSAGWDKLVKVWN 178 ******************987655 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00028 WD40_MABP1-WDR62_2nd 90 GvRvlkvspdgkhlasGDrsGniriydletleellkieahd 130 + v++vspdg +asG + G+ ++dl+ ++l+++e d FUN_001654-T1 194 YLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGGD 234 46799************************999999998765 PP == domain 4 score: -0.8 bits; conditional E-value: 1.5 WD40_MABP1-WDR62_2nd 24 ltcssDdtiRlWnl 37 ++ +D+ iR+W++ FUN_001654-T1 299 FAGYTDNLIRVWHV 312 23334555555544 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.6 0.2 2.7e-11 1.4e-08 10 172 .. 18 185 .. 10 188 .. 0.84 2 ! 29.2 0.0 1.2e-09 6.4e-07 48 171 .. 143 266 .. 136 271 .. 0.85 3 ! 7.2 0.0 0.0058 3.1 54 83 .. 284 313 .. 276 316 .. 0.89 Alignments for each domain: == domain 1 score: 34.6 bits; conditional E-value: 2.7e-11 WDR55 10 vvdisfhPse.diiavgtidGdvllykysneenenk.ellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysll 103 v++i+ P++ d i g+ d + ++++ + +e++ l+ h++ + +v s+dG+ +s s D ++++ d++ g +++++ ++ ++ FUN_001654-T1 18 VTQIATNPQDpDKILSGSRDKKLIVWNLTRDETNYGvAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAF 113 77888888765788899999999999988877654314567789****************************************988888888888 PP WDR55 104 videnllatGdddGtvklWDlRk.kkavmelkehedyisdlvv..deekklLlatsgdGtltvfnirkkkle 172 d++ +++G d +klW + k +++ + h+d +s++ + ++++ ++++++ d ++v+n+++ +l+ FUN_001654-T1 114 SADNRQIVSGSRDKSIKLWNTLGvCKYTIQDEGHSDWVSCVRFspNSSNPIIVSAGWDKLVKVWNLTNCRLK 185 99999**************98752688999999******998833567789999999********9998876 PP == domain 2 score: 29.2 bits; conditional E-value: 1.2e-09 WDR55 48 slehhkkscraveFsedGkk..lfsvskDksiavldvetgklkkkiekahespiysllvi.denllatGdddGtvklWDlRkkkavmelkehedyi 140 + e h++ + +v+Fs + ++ ++s+ Dk ++v ++++ +lk++ h+ ++ ++v d l+a+G dG+ lWDl + k +++l+ d+i FUN_001654-T1 143 QDEGHSDWVSCVRFSPNSSNpiIVSAGWDKLVKVWNLTNCRLKTNHI-GHQGYLNVVTVSpDGSLCASGGKDGMAMLWDLNEGKHLYTLE-GGDII 236 55779999999***99887544889999*********9998887655.7888899888764789********************999985.78*** PP WDR55 141 sdlvvdeekklLlatsgdGtltvfnirkkkl 171 ++l+++ ++ +L+a+ g t+++++++ k+l FUN_001654-T1 237 NSLCFSPNRYWLCAAVG-PTIKIWDLEGKSL 266 *******9999999998.8999999998876 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0058 WDR55 54 kscraveFsedGkklfsvskDksiavldve 83 c ++++s+dG++lf+ +D+ i+v +v+ FUN_001654-T1 284 ADCMSLAWSADGQTLFAGYTDNLIRVWHVT 313 5799********************998875 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.3 0.0 0.0006 0.32 135 175 .. 9 49 .. 1 56 [. 0.73 2 ! 23.9 0.0 4.3e-08 2.3e-05 139 193 .. 60 114 .. 47 131 .. 0.83 3 ! 11.5 0.1 0.00026 0.14 137 193 .. 142 201 .. 132 204 .. 0.78 4 ? 2.9 0.0 0.11 57 140 180 .. 190 230 .. 181 246 .. 0.74 5 ! 15.4 0.1 1.7e-05 0.009 267 322 .. 247 307 .. 232 315 .. 0.74 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0006 Beta-prop_SPT8 135 hylkakhsnvvnilrln.stedkflsgswdkkilewdlntgk 175 +lk+ h v+ + n ++ dk+lsgs dkk++ w+l ++ FUN_001654-T1 9 GTLKG-HDGWVTQIATNpQDPDKILSGSRDKKLIVWNLTRDE 49 56775.766665555441677****************98654 PP == domain 2 score: 23.9 bits; conditional E-value: 4.3e-08 Beta-prop_SPT8 139 akhsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgatselsalelr 193 ++h++ v+ + ++s+ + lsgswd + wdln g++++++ g+t ++ ++++ FUN_001654-T1 60 TGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFS 114 379*****9**************************************99888765 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00026 Beta-prop_SPT8 137 lk.akhsnvvnilrl..nstedkflsgswdkkilewdlntgkvineykgatselsalelr 193 ++ ++hs+ v+ +r+ ns++ ++s++wdk + w+l + ++ g+++ l + + FUN_001654-T1 142 IQdEGHSDWVSCVRFspNSSNPIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVS 201 44258********993345566799*************9988888888998888777665 PP == domain 4 score: 2.9 bits; conditional E-value: 0.11 Beta-prop_SPT8 140 khsnvvnilrlnstedkflsgswdkkilewdlntgkviney 180 +h+ +n++ ++ + sg+ d + wdln gk FUN_001654-T1 190 GHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTL 230 57777888888888888888888888888888888776555 PP == domain 5 score: 15.4 bits; conditional E-value: 1.7e-05 Beta-prop_SPT8 267 fltsGlnGsiniwdkrns...kapvlklergaktppw..clsacwsadGdyiyaGrrnacv 322 +l + + +i+iwd + ++ l++ + pp c+s wsadG++++aG + + FUN_001654-T1 247 WLCAAVGPTIKIWDLEGKslvDELTLDVISMGGKPPSadCMSLAWSADGQTLFAGYTDNLI 307 5677888899***96543111566777777777777445****************876655 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.0 9.5e-09 5e-06 184 290 .. 21 132 .. 10 133 .. 0.71 2 ! 27.6 0.0 4e-09 2.1e-06 7 110 .. 118 224 .. 118 236 .. 0.85 3 ? 5.2 0.0 0.028 15 223 249 .. 284 311 .. 234 316 .. 0.60 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 9.5e-09 Beta-prop_WDR90_POC16_2nd 184 vafspaklkhLlvstssnkllkldakt.....Grllrevsevhrsacsslavsedarylltag.dkvikvwdysmkldinfqvf 261 +a p++ +++l ++kl++ + + G r + h++ +s + +s+d+++ l+++ d ++++wd + + ++ f FUN_001654-T1 21 IATNPQDPDKILSGSRDKKLIVWNLTRdetnyGVAYR-ALTGHNHFVSDVVMSSDGQFALSGSwDATLRLWDLNAG--VTTRRF 101 5566666666666666666666543330000033333.3467999*************88765599******8765..56778* PP Beta-prop_WDR90_POC16_2nd 262 iGhsekvqqvaftpdqqevlsvG..daiflW 290 +Gh++ v vaf++d+++++s +i lW FUN_001654-T1 102 VGHTKDVLSVAFSADNRQIVSGSrdKSIKLW 132 ********************84311456666 PP == domain 2 score: 27.6 bits; conditional E-value: 4e-09 Beta-prop_WDR90_POC16_2nd 7 rqlatvseDetiriWdldtl.qqlydfsaseeaPcavafhPsk..qvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfs 87 rq++ s+D++i++W++ + + + + +++ ++v f P++ +++++ + +v+v+++++ +l +h h+g + +++s FUN_001654-T1 118 RQIVSGSRDKSIKLWNTLGVcKYTIQDEGHSDWVSCVRFSPNSsnPIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVS 201 688899*********9766514455556779999*******75225676666678***************************** PP Beta-prop_WDR90_POC16_2nd 88 pdgeylysacslGslalydasee 110 pdg++ s ++ G+ l+d +e FUN_001654-T1 202 PDGSLCASGGKDGMAMLWDLNEG 224 ****************9998775 PP == domain 3 score: 5.2 bits; conditional E-value: 0.028 Beta-prop_WDR90_POC16_2nd 223 sacsslavsedaryllta.gdkvikvwd 249 + c sla s d++ l ++ +d++i+vw FUN_001654-T1 284 ADCMSLAWSADGQTLFAGyTDNLIRVWH 311 3466666666666554432566666665 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.6 0.0 0.0042 2.2 43 80 .. 6 44 .. 2 56 .. 0.85 2 ! 30.4 0.1 4.7e-10 2.5e-07 11 103 .. 63 159 .. 54 167 .. 0.84 3 ! 17.2 0.0 4.9e-06 0.0026 18 156 .. 155 308 .. 151 313 .. 0.76 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0042 Beta-prop_IFT122_1st 43 tllqplkghkdtvycvaya.kdgkrfasgsadksviiwt 80 tl lkgh v +a +d ++ sgs dk +i+w FUN_001654-T1 6 TLRGTLKGHDGWVTQIATNpQDPDKILSGSRDKKLIVWN 44 67778******999988643899***************7 PP == domain 2 score: 30.4 bits; conditional E-value: 4.7e-10 Beta-prop_IFT122_1st 11 ehcindiafkpdgtqlil.aagsrllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegilkyt.....hnd 93 +h + d+ + dg + + + l ++d + g + + gh v va++ d +++ sgs dks+ +w + g+ kyt h d FUN_001654-T1 63 NHFVSDVVMSSDGQFALSgSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT--LGVCKYTiqdegHSD 149 7999********975544144678999*******************************************86..488888755555888 PP Beta-prop_IFT122_1st 94 aiqcvsynpi 103 + cv + p FUN_001654-T1 150 WVSCVRFSPN 159 9999999885 PP == domain 3 score: 17.2 bits; conditional E-value: 4.9e-06 Beta-prop_IFT122_1st 18 afkpdgtq.lilaagsrll..vydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegilkythn..daiqcvsyn 101 f p+ ++ +i++ag l v++ ++ l gh+ + +v+ + dg asg d ++w + eg yt + d i+ +++ FUN_001654-T1 155 RFSPNSSNpIIVSAGWDKLvkVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLN-EGKHLYTLEggDIINSLCFS 242 57777655267788865441378999999999*********************************864.777777754339******** PP Beta-prop_IFT122_1st 102 pithqlascsssdfglwspeqksvskhks...........sskiiccswtndgqylalgmfngiis 156 p + l+++ + +w e ks+ + s+ + +w+ dgq l g + +i FUN_001654-T1 243 PNRYWLCAAVGPTIKIWDLEGKSLVDELTldvismggkppSADCMSLAWSADGQTLFAGYTDNLIR 308 **********************97654321111111111256677778999999998888777765 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.06 32 121 156 .. 12 48 .. 1 52 [. 0.67 2 ! 13.0 0.1 9e-05 0.048 119 156 .. 58 95 .. 50 102 .. 0.84 3 ! 9.2 0.1 0.0012 0.66 121 154 .. 103 135 .. 92 148 .. 0.78 4 ! 9.1 0.1 0.0014 0.76 122 161 .. 146 187 .. 139 194 .. 0.84 5 ! 22.7 0.1 9.9e-08 5.3e-05 91 157 .. 159 225 .. 152 230 .. 0.91 6 ? 4.4 0.1 0.038 20 129 156 .. 288 315 .. 283 317 .] 0.88 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.06 NBCH_WD40 121 rqhkdvvscvavt.sdgsvlatGsydttvmvwevlra 156 + h v+ +a +d + +Gs+d ++vw+++r FUN_001654-T1 12 KGHDGWVTQIATNpQDPDKILSGSRDKKLIVWNLTRD 48 4566666666654246677788888888888888775 PP == domain 2 score: 13.0 bits; conditional E-value: 9e-05 NBCH_WD40 119 sirqhkdvvscvavtsdgsvlatGsydttvmvwevlra 156 ++ h+ vs v ++sdg++ +Gs+d+t+ +w++ + FUN_001654-T1 58 ALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAG 95 567799***************************98754 PP == domain 3 score: 9.2 bits; conditional E-value: 0.0012 NBCH_WD40 121 rqhkdvvscvavtsdgsvlatGsydttvmvwevl 154 + kdv+ +va ++d + +++Gs+d ++ +w++l FUN_001654-T1 103 GHTKDVL-SVAFSADNRQIVSGSRDKSIKLWNTL 135 4556766.5899*******************976 PP == domain 4 score: 9.1 bits; conditional E-value: 0.0014 NBCH_WD40 122 qhkdvvscvavtsdgs..vlatGsydttvmvwevlrarssek 161 h d vscv + + s ++++ +d v vw++++ r +++ FUN_001654-T1 146 GHSDWVSCVRFSPNSSnpIIVSAGWDKLVKVWNLTNCRLKTN 187 69*******99987765599**************99887765 PP == domain 5 score: 22.7 bits; conditional E-value: 9.9e-08 NBCH_WD40 91 ksenfliscGnwensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlrar 157 +s+n +i w+ +v l++ rl + h+ + v+v+ dgs+ a+G +d m+w++ +++ FUN_001654-T1 159 NSSNPIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGK 225 56777888889**************************************************998765 PP == domain 6 score: 4.4 bits; conditional E-value: 0.038 NBCH_WD40 129 cvavtsdgsvlatGsydttvmvwevlra 156 ++a ++dg+ l +G d + vw+v+r+ FUN_001654-T1 288 SLAWSADGQTLFAGYTDNLIRVWHVTRV 315 567899*******************986 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.8 0.0 0.0083 4.4 58 130 .. 27 104 .. 16 110 .. 0.74 2 ! 30.2 0.2 6.1e-10 3.3e-07 2 115 .. 108 218 .. 106 232 .. 0.90 3 ! 13.2 0.0 9.6e-05 0.051 2 79 .. 236 315 .. 235 317 .] 0.72 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0083 WDR90_beta-prop_4th 58 eqqqvvaGysdGtlrvfsisrtemel.....klhphavaltaiaysadGqtilsgdkdGlvavssprtGvtlrvlsdh 130 + +++ +G d l v++++r e + l h+ + ++ s+dGq lsg d + + +Gvt r + h FUN_001654-T1 27 DPDKILSGSRDKKLIVWNLTRDETNYgvayrALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGH 104 456777888888888888888776642222235678888999999999999999999999999999999998877666 PP == domain 2 score: 30.2 bits; conditional E-value: 6.1e-10 WDR90_beta-prop_4th 2 vnevvfspdeshlatcsedGsvrvws.lasmelvvqfqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelklhphav 90 v v+fs+d++++ + s d s+++w l + + +q + ++ c+ +sp+ss+ v aG+ d ++v+++++ ++ h+ FUN_001654-T1 108 VLSVAFSADNRQIVSGSRDKSIKLWNtLGVCKYTIQDEGHSDWVSCVRFSPNSSN---PIIVSAGW-DKLVKVWNLTNCRLKTNHIGHQG 193 6689*********************6378899********************998...67888887.889******************** PP WDR90_beta-prop_4th 91 altaiaysadGqtilsgdkdGlvav 115 l ++ s dG + sg+kdG+ + FUN_001654-T1 194 YLNVVTVSPDGSLCASGGKDGMAML 218 *********************9766 PP == domain 3 score: 13.2 bits; conditional E-value: 9.6e-05 WDR90_beta-prop_4th 2 vnevvfspdeshlatcsedG.svrvwslasmelv..vqfqvlnqsclclawspsssar.aeqqqvvaGysdGtlrvfsisrt 79 +n ++fsp+ c+ G ++++w l+ + lv + ++v++ + + + s a a+ q++ aGy+d +rv+ ++r+ FUN_001654-T1 236 INSLCFSPNRY--WLCAAVGpTIKIWDLEGKSLVdeLTLDVISMGGKPPSADCMSLAWsADGQTLFAGYTDNLIRVWHVTRV 315 68899999753..4455544389******99999445567887765554444444433378999**************9986 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.7 0.2 1.3e-10 7e-08 113 263 .. 21 177 .. 5 180 .. 0.89 2 ! 21.9 0.0 2.6e-07 0.00014 132 263 .. 174 310 .. 172 312 .. 0.84 Alignments for each domain: == domain 1 score: 32.7 bits; conditional E-value: 1.3e-10 Beta-prop_WDR36-Utp21_1st 113 llhpsTYlnKilvgskqGslqlwNirtgkliytf.....ksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqe 191 + + + +Kil gs++ +l +wN+ + y + ++ ++ ++ ++ s + g + ++ l +++++ t ++ + FUN_001654-T1 21 IATNPQDPDKILSGSRDKKLIVWNLTRDETNYGVayralTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGH 104 555555569***********************9944433366699*************************************** PP Beta-prop_WDR36-Utp21_1st 192 egpvtsisFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpg..qpllvtsgaDNslkew 263 ++ v s++F D+++ +++gs++ +i lw+ ++ ++ H+ v++++f p+ +p++v++g D +k+w FUN_001654-T1 105 TKDVLSVAFSADNRQ-IVSGSRDKSIKLWNTLGVCKYTIQDEGHSDWVSCVRFSPNssNPIIVSAGWDKLVKVW 177 9***********876.689************9999******************9975589************** PP == domain 2 score: 21.9 bits; conditional E-value: 2.6e-07 Beta-prop_WDR36-Utp21_1st 132 lqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssG 215 +++wN+ +++l + + ++ +++ sp +++a g ++G +l +++ ++ l +l+ + ++s++F + +++ FUN_001654-T1 174 VKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGG-DIINSLCFSPNRYW--LCAAVGP 254 689********999999*****************************************99.99******997544..4455567 PP Beta-prop_WDR36-Utp21_1st 216 dialwdLekrrlvhvlrnaHeg........gvtkleflpgqpllvtsgaDNslkew 263 +i +wdLe ++lv l+ + + +l + ++ + l +DN +++w FUN_001654-T1 255 TIKIWDLEGKSLVDELTLDVISmggkppsaDCMSLAWSADGQTLFAGYTDNLIRVW 310 8*********7777664322222355666688999999999999999999999999 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.1 0.003 1.6 167 228 .. 28 93 .. 8 98 .. 0.78 2 ! 26.2 0.3 1.3e-08 7.1e-06 3 99 .. 99 182 .. 97 187 .. 0.84 3 ! 12.9 0.1 0.00015 0.08 180 228 .. 175 222 .. 165 232 .. 0.82 4 ? 5.6 0.0 0.026 14 40 96 .. 253 312 .. 233 315 .. 0.75 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.003 Beta-prop_EML 167 ngdvitGdsnGnilvWskgtn....kiskavkkahegsvfsllvlkdgtllsgggkdgkivawdan 228 +++++G + +++vW+ +++ + + + h++ v+ + +++dg++ +g d ++ wd n FUN_001654-T1 28 PDKILSGSRDKKLIVWNLTRDetnyGVAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLN 93 467899999999****955441123456666789**************999999999999999865 PP == domain 2 score: 26.2 bits; conditional E-value: 1.3e-08 Beta-prop_EML 3 RhYlgHtddikclavhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqk 98 R ++gHt+d+ ++a ++ +++G i+ W++ + + + ++g ++ vsc+ Fs +++ ++v ++ + vW+ ++ FUN_001654-T1 99 RRFVGHTKDVLSVAFSADNRQIVSGSRD----------KSIKLWNTLGVCKYTIQDEG-HSDWVSCVRFSPNSS--NPIIVSAGWDKLVKVWNLTN 181 889*********************9964..........47*********999998777.9999*******9775..55666777788999999876 PP Beta-prop_EML 99 g 99 FUN_001654-T1 182 C 182 5 PP == domain 3 score: 12.9 bits; conditional E-value: 0.00015 Beta-prop_EML 180 lvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivawdan 228 vW+ ++ +++ + + h+g + ++v++dg+l +ggkdg+++ wd n FUN_001654-T1 175 KVWNLTNCRLKTN-HIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLN 222 5788766666554.559*****************************965 PP == domain 4 score: 5.6 bits; conditional E-value: 0.026 Beta-prop_EML 40 kphiriWdsetle.....tlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdw 96 p+i+iWd e + tl v+++g + c++ +++g++L+a ++n + vW++ FUN_001654-T1 253 GPTIKIWDLEGKSlvdelTLDVISMGGKPPSADCMSLAWSADGQTLFAGYTDN--LIRVWHV 312 48899999764331133378888888888888899998889999999987766..8888876 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.001 0.54 30 66 .. 10 46 .. 6 51 .. 0.94 2 ! 18.8 0.1 2.2e-06 0.0012 29 92 .. 57 120 .. 49 121 .. 0.83 3 ! 8.0 0.0 0.0043 2.3 31 65 .. 101 134 .. 98 142 .. 0.88 4 ! 7.0 0.1 0.0086 4.6 32 78 .. 145 191 .. 136 194 .. 0.81 5 ! 10.6 0.0 0.00066 0.35 177 240 .. 186 245 .. 183 270 .. 0.83 6 ? -0.8 0.0 2 1.1e+03 232 257 .. 287 312 .. 281 315 .. 0.79 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.001 Beta-prop_WDR75_1st 30 elkghtdlvtGvalnpsnhlqvyscsldgtvrlwdft 66 +lkgh vt +a np++ ++ s s d + +w+ t FUN_001654-T1 10 TLKGHDGWVTQIATNPQDPDKILSGSRDKKLIVWNLT 46 69********************************987 PP == domain 2 score: 18.8 bits; conditional E-value: 2.2e-06 Beta-prop_WDR75_1st 29 helkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktfvvgy.kilslyvsakhegv 92 ++l gh++ v+ v++ ++ s s d+t+rlwd g+ + fv ++ls+ sa+++++ FUN_001654-T1 57 RALTGHNHFVSDVVMSSDGQFA-LSGSWDATLRLWDLNAGVTTRRFVGHTkDVLSVAFSADNRQI 120 789***********99888875.69********************99654158888877776655 PP == domain 3 score: 8.0 bits; conditional E-value: 0.0043 Beta-prop_WDR75_1st 31 lkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 + ght+ v va+ n+ q+ s s d +++lw+ FUN_001654-T1 101 FVGHTKDVLSVAFSADNR-QIVSGSRDKSIKLWNT 134 679**********99886.9*************85 PP == domain 4 score: 7.0 bits; conditional E-value: 0.0086 Beta-prop_WDR75_1st 32 kghtdlvtGvalnpsnhl.qvyscsldgtvrlwdftdgiliktfvvgy 78 +gh+d v+ v + p+ + s+ d v++w+ t+ +kt +g+ FUN_001654-T1 145 EGHSDWVSCVRFSPNSSNpIIVSAGWDKLVKVWNLTNC-RLKTNHIGH 191 79***********976541578999*********9975.567777765 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00066 Beta-prop_WDR75_1st 177 edkkGaknaftcvachpkddciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeG 240 +++ G + + +v++ p+ a+G +dG lw + k+ yt d+++sl+f+p+ FUN_001654-T1 186 TNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEG----GDIINSLCFSPNR 245 56778888999999999999999999999999999888898999875....5889999999875 PP == domain 6 score: -0.8 bits; conditional E-value: 2 Beta-prop_WDR75_1st 232 sslvftpeGtnllsGGvesvlvqwry 257 +sl+++++G l++G + ++ w++ FUN_001654-T1 287 MSLAWSADGQTLFAGYTDNLIRVWHV 312 67888889999998888888888876 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.6 0.8 4.3e-09 2.3e-06 40 156 .. 65 182 .. 40 183 .. 0.76 2 ! 26.7 0.5 8.1e-09 4.3e-06 39 154 .. 106 222 .. 104 229 .. 0.77 3 ! 7.3 0.0 0.0066 3.5 39 79 .. 234 271 .. 213 280 .. 0.74 4 ? 1.1 0.0 0.5 2.6e+02 43 70 .. 288 313 .. 280 316 .. 0.76 Alignments for each domain: == domain 1 score: 27.6 bits; conditional E-value: 4.3e-09 WD40_MABP1-WDR62_1st 40 alsalafspdGkylvtGesghlpavrvwdvaeksqvaelqkhkygvacvafspnekyivsvgyqhdmvvnvwdw..kkdvvvaankvss 126 +s + +s+dG++ ++G ++r+wd++ + + +h v vafs++++ ivs d+ +++w+ + + + s FUN_001654-T1 65 FVSDVVMSSDGQFALSGSW--DATLRLWDLNAGVTTRRFVGHTKDVLSVAFSADNRQIVSG--SRDKSIKLWNTlgVCKYTIQDEGHSD 149 5677888999999999864..5789999999999999999999999999999999999986..56777777775222344566777888 PP WD40_MABP1-WDR62_1st 127 kvtavsfsedssy..fvtvG.nrhvkfwyldas 156 v +v fs +ss v++G ++ vk w l ++ FUN_001654-T1 150 WVSCVRFSPNSSNpiIVSAGwDKLVKVWNLTNC 182 999999999888622566664577999998877 PP == domain 2 score: 26.7 bits; conditional E-value: 8.1e-09 WD40_MABP1-WDR62_1st 39 kalsalafspdGkylvtGesghlpavrvwdvaeksqva.elqkhkygvacvafspnekyivsvgyqhdmvvnvwdwkkdvvvaankvss 126 k + ++afs+d + +v+G ++++w+ ++ + + ++h v+cv fspn++ + v +d++v+vw+ ++ + +n + FUN_001654-T1 106 KDVLSVAFSADNRQIVSGSRD--KSIKLWNTLGVCKYTiQDEGHSDWVSCVRFSPNSSNPIIVSAGWDKLVKVWNLT-NCRLKTNHIGH 191 667789************765..79*****98877654156789999**********9988899999*******975.77888899876 PP WD40_MABP1-WDR62_1st 127 k..vtavsfsedssyfvtvGnrhv.kfwyld 154 + + v+ s d+s + G+ + +w l+ FUN_001654-T1 192 QgyLNVVTVSPDGSLCASGGKDGMaMLWDLN 222 5335677888888877777765441346555 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0066 WD40_MABP1-WDR62_1st 39 kalsalafspdGkylvtGesghlpavrvwdvaeksqvaelq 79 + +l+fsp+ +l + g p++++wd++ ks v el+ FUN_001654-T1 234 DIINSLCFSPNRYWL-CAAVG--PTIKIWDLEGKSLVDELT 271 56899*****86555.55566..**************9986 PP == domain 4 score: 1.1 bits; conditional E-value: 0.5 WD40_MABP1-WDR62_1st 43 alafspdGkylvtGesghlpavrvwdva 70 +la+s+dG+ l +G + +rvw v+ FUN_001654-T1 288 SLAWSADGQTLFAGYTD--NLIRVWHVT 313 68888888888888776..568888875 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.0 9.4e-07 0.0005 163 273 .. 13 121 .. 4 125 .. 0.85 2 ? 3.7 0.0 0.09 48 213 244 .. 104 134 .. 96 137 .. 0.83 3 ! 12.9 0.8 0.00014 0.074 207 249 .. 141 184 .. 126 202 .. 0.82 4 ? 0.1 0.0 1.2 6.3e+02 231 249 .. 208 226 .. 190 243 .. 0.80 5 ? 4.1 0.0 0.07 37 182 244 .. 250 312 .. 230 315 .. 0.60 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 9.4e-07 Beta-prop_RIG_2nd 163 llsryitdiawsplesnklAvvandkvivilefkeeernletlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekeelti 254 ++ +t+ia++p + +k+ ++dk++++ +++++e+n + + +++ +++v s+ + ls s d ++++Wdl+++ ++ + FUN_001654-T1 13 GHDGWVTQIATNPQDPDKILSGSRDKKLIVWNLTRDETNYGVAY-RALTGHNHFVSDVVMSSDG-QFALSGSWDATLRLWDLNAGVTTRRFV 102 56789*****************************8888877654.5567899999***999876.567899***************999889 PP Beta-prop_RIG_2nd 255 tykcpmlcglFlPtdeniv 273 ++ +l+ F+ + +iv FUN_001654-T1 103 GHTKDVLSVAFSADNRQIV 121 9999999999987777665 PP == domain 2 score: 3.7 bits; conditional E-value: 0.09 Beta-prop_RIG_2nd 213 ekasitsvkwsnansnlllsfsidgkvkvWdl 244 + + + sv++s n +++s s d ++k+W++ FUN_001654-T1 104 HTKDVLSVAFSADNR-QIVSGSRDKSIKLWNT 134 778899999998765.677999********97 PP == domain 3 score: 12.9 bits; conditional E-value: 0.00014 Beta-prop_RIG_2nd 207 kitasaekasitsvkwsnansn.lllsfsidgkvkvWdleepek 249 +i+ + +++ +++v++s+++sn +++s + d vkvW+l + + FUN_001654-T1 141 TIQDEGHSDWVSCVRFSPNSSNpIIVSAGWDKLVKVWNLTNCRL 184 6677789999*******9997637889***********987655 PP == domain 4 score: 0.1 bits; conditional E-value: 1.2 Beta-prop_RIG_2nd 231 lsfsidgkvkvWdleepek 249 s + dg + +Wdl+e+++ FUN_001654-T1 208 ASGGKDGMAMLWDLNEGKH 226 5677899999999999876 PP == domain 5 score: 4.1 bits; conditional E-value: 0.07 Beta-prop_RIG_2nd 182 Avvandkvivilefkeeernlet.lkkitasaekasitsvkwsnansnlllsfsidgkvkvWdl 244 A v+ + +i le k+ ++l+ + ++ ++++a s++ws + l+ d+ ++vW + FUN_001654-T1 250 AAVGPTIKIWDLEGKSLVDELTLdVISMGGKPPSADCMSLAWSADGQTLFA-GYTDNLIRVWHV 312 555555444444444444444432445556677888888888877665554.477888888876 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 1.2e-07 6.4e-05 203 280 .] 14 90 .. 10 90 .. 0.92 2 ! 11.7 0.1 0.00034 0.18 202 280 .] 103 177 .. 93 177 .. 0.77 3 ? 0.2 0.0 1.1 5.9e+02 220 239 .. 207 225 .. 180 259 .. 0.79 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 1.2e-07 Beta-prop_EIPR1 203 gfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 ++g v+++ +p+ + k+l+ d + ++ + d + + ++l +h+H v+ v + + ++ ls+s d tl+Lw FUN_001654-T1 14 HDGWVTQIATNPQDPDKILSGSRDKKLIVWNLTRDETNYGVAYRALTGHNHFVSDVVMSSD-GQFALSGSWDATLRLW 90 58999***************************88999999999*************99765.789************* PP == domain 2 score: 11.7 bits; conditional E-value: 0.00034 Beta-prop_EIPR1 202 hgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfyde.LilscssdstlkLw 280 + + v +v f+ + ++++ d ++++ g +++++++ ++h+ +v+ v+f p+ + +i+s++ d+ +k w FUN_001654-T1 103 GHTKDVLSVAFSAD-NRQIVSGSRDKSIKLWNTL--G-VCKYTIQD-EGHSDWVSCVRFSPNSSNpIIVSAGWDKLVKVW 177 55677888888765.5678899999999999877..3.44555544.8*************87543999*********99 PP == domain 3 score: 0.2 bits; conditional E-value: 1.1 Beta-prop_EIPR1 220 lltagddgvvlihDiRydgs 239 ++ g+dg+ +++D+ +g+ FUN_001654-T1 207 CASGGKDGMAMLWDLN-EGK 225 4678999999999998.665 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.1 2.3e-05 0.012 113 216 .. 18 127 .. 9 131 .. 0.75 2 ! 15.5 0.8 1.9e-05 0.01 37 182 .. 125 261 .. 120 269 .. 0.71 3 ! 16.6 0.1 8.9e-06 0.0047 78 141 .. 251 313 .. 236 316 .. 0.55 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.3e-05 Beta-prop_Aladin 113 vtsvaWspkG.dlLvsaspvdtsilvWdvaketa...vpLrrvgggg..vsllkwspdgskllaatpssvfrvwetet.WtcerWtvlkgrvq 198 vt++a +p+ d ++s+s d++++vW+ ++++ v+ r +g++ vs + s dg+ l+++ + +r+w+ + t+ r+ + v FUN_001654-T1 18 VTQIATNPQDpDKILSGS-RDKKLIVWNLTRDETnygVAYRALTGHNhfVSDVVMSSDGQFALSGSWDATLRLWDLNAgVTTRRFVGHTKDVL 109 888999988625566665.7999****9976554222777777775422566789********************976256777888999999 PP Beta-prop_Aladin 199 aacwspdgsvllfateee 216 + ++s+d++ ++ ++++ FUN_001654-T1 110 SVAFSADNRQIVSGSRDK 127 99***9999888766665 PP == domain 2 score: 15.5 bits; conditional E-value: 1.9e-05 Beta-prop_Aladin 37 lddsirvytsesslvplLkhk.lqksvaslaWrPlsaselav..acesgvlvWtvdptslatrpssssaqvLkrpghspvtsvaWspkGdlLv 126 +d si+++++ + +++ + v+++ + P+s+ + v + ++ v vW++ + l t +++ ++g+ v++v sp+G+l + FUN_001654-T1 125 RDKSIKLWNTLGVCKYTIQDEgHSDWVSCVRFSPNSSNPIIVsaGWDKLVKVWNLTNCRLKT-------NHIGHQGYLNVVTV--SPDGSLCA 208 68888888888777777765514566999999999999887733568999999998865544.......35678889888877..69999877 PP Beta-prop_Aladin 127 saspvdtsilvWdvaketavpLrrvggggvsl.lkwspdgskllaatpssvfrvwet 182 s+ +d ++Wd ++ L gg ++ l +sp ++ l a+++ ++w+ FUN_001654-T1 209 SGG-KDGMAMLWDLNE--GKHLYTLEGGDIINsLCFSP-NRYWLCAAVGPTIKIWDL 261 765.577777899865..45566666666655155555.566778888999999986 PP == domain 3 score: 16.6 bits; conditional E-value: 8.9e-06 Beta-prop_Aladin 78 acesgvlvWtvdptslatrpssssaqvLkrpghspvtsvaWspkGdlLvsaspvdtsilvWdva 141 a ++ +W+++ +sl+ + + +++ +p + +s+aWs +G++L + +d+ i vW+v FUN_001654-T1 251 AVGPTIKIWDLEGKSLVDELTLDVISMGGKPPSADCMSLAWSADGQTLFA-GYTDNLIRVWHVT 313 33344556666666666666666666666666666666666666666553.3555666666554 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.1 0.12 63 12 29 .. 28 45 .. 14 52 .. 0.76 2 ? 5.8 0.1 0.035 19 12 32 .. 75 95 .. 62 117 .. 0.74 3 ! 11.7 0.1 0.00054 0.29 12 29 .. 117 134 .. 104 139 .. 0.79 4 ! 11.3 0.1 0.00068 0.36 1 32 [. 147 182 .. 147 187 .. 0.74 5 ? 1.1 0.0 1.1 5.6e+02 13 35 .. 205 227 .. 191 246 .. 0.72 6 ? 2.8 0.0 0.31 1.6e+02 17 35 .. 249 267 .. 234 271 .. 0.82 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.12 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdr 29 d i+s s D+++ +W+ FUN_001654-T1 28 PDKILSGSRDKKLIVWNL 45 479*************86 PP == domain 2 score: 5.8 bits; conditional E-value: 0.035 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretk 32 + +s s D t++lWd + FUN_001654-T1 75 GQFALSGSWDATLRLWDLNAG 95 456789***********8764 PP == domain 3 score: 11.7 bits; conditional E-value: 0.00054 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdr 29 + i+s s D+++KlW++ FUN_001654-T1 117 NRQIVSGSRDKSIKLWNT 134 568*************86 PP == domain 4 score: 11.3 bits; conditional E-value: 0.00068 Beta-prop_TEP1_C 1 hsdrisalklt....ddliisAseDrtvKlWdretk 32 hsd +s ++ + +i+sA D+ vK+W+ ++ FUN_001654-T1 147 HSDWVSCVRFSpnssNPIIVSAGWDKLVKVWNLTNC 182 777777777641111568*************98765 PP == domain 5 score: 1.1 bits; conditional E-value: 1.1 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdretkkqv 35 +l s +D lWd ++ k + FUN_001654-T1 205 SLCASGGKDGMAMLWDLNEGKHL 227 455566799999****9999976 PP == domain 6 score: 2.8 bits; conditional E-value: 0.31 Beta-prop_TEP1_C 17 sAseDrtvKlWdretkkqv 35 A+ t+K+Wd e k +v FUN_001654-T1 249 CAAVGPTIKIWDLEGKSLV 267 5777889*****9888776 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 1.0 4.6e-07 0.00024 318 426 .. 30 145 .. 10 154 .. 0.82 2 ! 17.2 0.1 4.7e-06 0.0025 319 413 .. 165 260 .. 159 266 .. 0.75 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 4.6e-07 Beta-prop_SCAP 318 rvvtGsqdhtvrvyrle.d....scclftlqGhsGgitavyidqtmvla.sGGqdGaiclwdvltGsrvshvyghrGdvtslvctt..scvissG 404 ++++Gs+d + v+ l d +l Gh ++ v + +a sG d ++ lwd+ +G gh dv s+ +++ ++s FUN_001654-T1 30 KILSGSRDKKLIVWNLTrDetnyGVAYRALTGHNHFVSDVVMSSDGQFAlSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFSAdnRQIVSGS 124 6788999999999988522111134566899******99998766555439999***************************99876215688888 PP Beta-prop_SCAP 405 lddlisiwdrstgiklysiqqe 426 d i +w+ + g+ y+iq e FUN_001654-T1 125 RDKSIKLWN-TLGVCKYTIQDE 145 999*****8.578899***987 PP == domain 2 score: 17.2 bits; conditional E-value: 4.7e-06 Beta-prop_SCAP 319 vvtGsqdhtvrvyrledscclft.lqGhsGgitavyid.qtmvlasGGqdGaiclwdvltGsrvshvyghr.Gdvtslvct..tscvissGlddl 408 +v+ d v+v+ l + c l t Gh G + v + + + asGG+dG lwd+ G h+y+ Gd+ +c + + + + + FUN_001654-T1 165 IVSAGWDKLVKVWNLTN-CRLKTnHIGHQGYLNVVTVSpDGSLCASGGKDGMAMLWDLNEGK---HLYTLEgGDIINSLCFspNRYWLCAAVGPT 255 5677789999****986.77777256****99999986245677*************99885...677754268776666412456677777777 PP Beta-prop_SCAP 409 isiwd 413 i iwd FUN_001654-T1 256 IKIWD 260 77777 PP >> Beta-prop_WDR75_2nd WD repeat-containing protein 75 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.5 0.1 0.0079 4.2 101 231 .. 13 135 .. 3 140 .. 0.68 2 ! 24.1 0.1 3.5e-08 1.9e-05 99 268 .. 144 299 .. 133 305 .. 0.87 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0079 Beta-prop_WDR75_2nd 101 phedkitalcfseseesttllvtaskdgkfkvwllaedsdtekesaswscdfvGsyhelkatnccfsedgsl.lavsfeevvtvwesetw 189 h++ +t++ ++++ +++ s+d+k+ vw l++d+ ++ +++ G h++ + +s+dg + l+ s++ ++ +w+ ++ FUN_001654-T1 13 GHDGWVTQIATNPQDP--DKILSGSRDKKLIVWNLTRDETNY--GVAYRA-LTG--HNHFVSDVVMSSDGQFaLSGSWDATLRLWDLNAG 95 5777888887777666..677889999999999999887665..444432.344..6666677888888875488899999999998887 PP Beta-prop_WDR75_2nd 190 elkltlcqppgkirdlcfGrlscskyllgttdknllccwnll 231 + + ++ +++f + +++ + ++ + wn l FUN_001654-T1 96 VTTRRFVGHTKDVLSVAFSA--DNRQIVSGSRDKSIKLWNTL 135 77777777777777777753..33445555555556667765 PP == domain 2 score: 24.1 bits; conditional E-value: 3.5e-08 Beta-prop_WDR75_2nd 99 taphedkitalcfseseesttllvtaskdgkfkvwllaedsdtekesaswscdfvGsyhelkatnccfsedgsllavsfee.vvtvwese 187 h+d ++++ fs++++ +++v+a+ d+ kvw l++ + + +++G h+ + ++s dgsl a + ++ + +w+ + FUN_001654-T1 144 DEGHSDWVSCVRFSPNSS-NPIIVSAGWDKLVKVWNLTNCR--------LKTNHIG--HQGYLNVVTVSPDGSLCASGGKDgMAMLWDLN 222 567************999.9****************98644........4567888..6667778899********9988725568***9 PP Beta-prop_WDR75_2nd 188 twelkltlcqppgkirdlcfGrlscskyllgttdknllccwnlltcalewsakldvavlqadplseniaafslaseksdlf 268 + + tl i++lcf s +y l ++ + w+l +l +ldv+ + p s + +++++++ lf FUN_001654-T1 223 EGKHLYTLE-GGDIINSLCF---SPNRYWLCAAVGPTIKIWDLEGKSLVDELTLDVISMGGKPPSADCMSLAWSADGQTLF 299 999999984.5677999**9...689************************************************9999998 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.075 40 35 89 .. 60 114 .. 31 116 .. 0.83 2 ? 2.7 0.0 0.41 2.2e+02 37 67 .. 104 134 .. 98 159 .. 0.74 3 ! 8.7 0.0 0.0054 2.8 29 84 .. 176 237 .. 164 244 .. 0.78 4 ? 3.5 0.0 0.22 1.2e+02 38 76 .. 233 270 .. 227 278 .. 0.83 5 ! 12.2 0.0 0.00042 0.22 39 67 .. 284 312 .. 257 315 .. 0.87 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.075 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdkitcleWa 89 +++ v+++ + dG++ + d ++rl d + g + + + +++++ ++ ++ FUN_001654-T1 60 TGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVAFS 114 5677789999999*************************99999888888888776 PP == domain 2 score: 2.7 bits; conditional E-value: 0.41 ANAPC4_WD40 37 edsevtslaWkpdGklLavaysdgevrlldv 67 +++ v s+a++ d + ++ + d +++l + FUN_001654-T1 104 HTKDVLSVAFSADNRQIVSGSRDKSIKLWNT 134 567899999************9999999875 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0054 ANAPC4_WD40 29 vwkl.......seekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdkit 84 vw+l ++ ++++ + + +pdG l a + +dg l d ++gk + +l+ ++ i+ FUN_001654-T1 176 VWNLtncrlktNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGGDI-IN 237 55555555554455667777788889*************************999876665.55 PP == domain 4 score: 3.5 bits; conditional E-value: 0.22 ANAPC4_WD40 38 dsevtslaWkpdGklLavaysdgevrlldvesgklvhsl 76 + ++sl+++p+ L+ a+ ++++ d e + lv +l FUN_001654-T1 233 GDIINSLCFSPNRYWLCAAVGP-TIKIWDLEGKSLVDEL 270 56799************99875.7999999999888776 PP == domain 5 score: 12.2 bits; conditional E-value: 0.00042 ANAPC4_WD40 39 sevtslaWkpdGklLavaysdgevrlldv 67 + slaW+ dG+ L +y d+ +r+ +v FUN_001654-T1 284 ADCMSLAWSADGQTLFAGYTDNLIRVWHV 312 56679********************9987 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.0 0.00044 0.23 106 151 .. 9 56 .. 3 60 .. 0.83 2 ! 14.0 0.6 4.7e-05 0.025 109 153 .. 60 105 .. 53 111 .. 0.84 3 ! 6.7 0.1 0.0079 4.2 110 139 .. 103 133 .. 97 141 .. 0.87 4 ! 7.9 0.2 0.0034 1.8 109 150 .. 145 189 .. 137 202 .. 0.82 5 ? -1.2 0.0 2 1e+03 114 143 .. 194 224 .. 186 231 .. 0.70 6 ? -0.3 0.1 1.1 5.7e+02 99 141 .. 271 313 .. 266 315 .. 0.78 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00044 Beta-prop_DCAF12 106 Gdrkghkdwifaiawlsd..tvavsGsrdgtlalwrvdpdklnasial 151 G kgh w++ ia + ++sGsrd l +w++ d++n +a FUN_001654-T1 9 GTLKGHDGWVTQIATNPQdpDKILSGSRDKKLIVWNLTRDETNYGVAY 56 6679*********98644125789****************99988775 PP == domain 2 score: 14.0 bits; conditional E-value: 4.7e-05 Beta-prop_DCAF12 109 kghkdwifaiawlsd.tvavsGsrdgtlalwrvdpdklnasialkn 153 gh+++++ ++ sd + a+sGs+d+tl lw ++ +++ ++ + FUN_001654-T1 60 TGHNHFVSDVVMSSDgQFALSGSWDATLRLWDLNAGVTTRRFVGHT 105 69*******999999468****************998887776665 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0079 Beta-prop_DCAF12 110 ghkdwifaiawlsdt.vavsGsrdgtlalwr 139 gh++ + ++a+ +d+ +vsGsrd ++ lw+ FUN_001654-T1 103 GHTKDVLSVAFSADNrQIVSGSRDKSIKLWN 133 8999999999999873589***********7 PP == domain 4 score: 7.9 bits; conditional E-value: 0.0034 Beta-prop_DCAF12 109 kghkdwifaiawl...sdtvavsGsrdgtlalwrvdpdklnasia 150 +gh+dw++++ + s+ ++vs +d + +w++ + +l++++ FUN_001654-T1 145 EGHSDWVSCVRFSpnsSNPIIVSAGWDKLVKVWNLTNCRLKTNHI 189 79********9853336789**************99888776655 PP == domain 5 score: -1.2 bits; conditional E-value: 2 Beta-prop_DCAF12 114 wifaiawlsd.tvavsGsrdgtlalwrvdpd 143 ++ ++ d ++ sG +dg lw +++ FUN_001654-T1 194 YLNVVTVSPDgSLCASGGKDGMAMLWDLNEG 224 5554444444257889999999999999865 PP == domain 6 score: -0.3 bits; conditional E-value: 1.1 Beta-prop_DCAF12 99 tldPlclGdrkghkdwifaiawlsdt.vavsGsrdgtlalwrvd 141 tld +++G + d +++aw +d +G +d + +w+v FUN_001654-T1 271 TLDVISMGGKPPSADC-MSLAWSADGqTLFAGYTDNLIRVWHVT 313 6788888888877775.579999986145689999999999985 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.5 2.6e+02 101 120 .. 27 46 .. 9 55 .. 0.69 2 ! 15.7 2.3 1.3e-05 0.0068 33 180 .. 54 199 .. 33 201 .. 0.75 3 ! 7.4 0.0 0.0043 2.3 51 81 .. 202 232 .. 190 271 .. 0.84 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.5 Beta-prop_WDR41 101 ksdliltassdktvivwdie 120 d il+ s dk +ivw++ FUN_001654-T1 27 DPDKILSGSRDKKLIVWNLT 46 44567888888888888764 PP == domain 2 score: 15.7 bits; conditional E-value: 1.3e-05 Beta-prop_WDR41 33 telsvlkehkdivrflvqiddfrfa.sagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwd....ies 121 ++l +h+ v +v d +fa s + d ++ lwd+++g + ght+++ +++ f+a++ i++ s dk++ +w+ ++ FUN_001654-T1 54 VAYRALTGHNHFVSDVVMSSDGQFAlSGSWDATLRLWDLNAGVTTRRFVGHTKDVLSVA-FSADN------RQIVSGSRDKSIKLWNtlgvCKY 140 5567899****************9846678************************98864.65543......348899*********96555677 PP Beta-prop_WDR41 122 grqlkkisdfqstvksltvlerldlwlsggsd..lrvwnr.dlellcktsyfvdagisalie 180 q + sd+ s+v+ + + +s g d ++vwn +++l kt++ + g +++ FUN_001654-T1 141 TIQDEGHSDWVSCVRFSP-NSSNPIIVSAGWDklVKVWNLtNCRL--KTNHIGHQGYLNVVT 199 778888899999988654.45556666666554578999613444..778888887777765 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0043 Beta-prop_WDR41 51 iddfrfasagddgivflwdvqtgeillelhg 81 d as g dg+ +lwd++ g+ l+ l g FUN_001654-T1 202 PDGSLCASGGKDGMAMLWDLNEGKHLYTLEG 232 5666789********************9998 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.0 0.0052 2.7 218 273 .. 53 107 .. 26 113 .. 0.77 2 ! 15.1 0.1 2.1e-05 0.011 230 307 .. 106 184 .. 104 188 .. 0.92 3 ? 1.9 0.0 0.21 1.1e+02 270 311 .. 188 230 .. 185 243 .. 0.73 4 ? -1.4 0.0 2.2 1.2e+03 241 264 .. 244 267 .. 235 274 .. 0.78 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0052 Beta-prop_DCAF4 218 gkgwkatrlfhdsavtsvqllqeeqlllaadmaGkiklwdlratkcvkqyeGhvne 273 g +++a h+ v+ v + + q+ l+ +++lwdl a + +++ Gh+ + FUN_001654-T1 53 GVAYRAL-TGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVGHTKD 107 4444443.3588889999999999*****************************976 PP == domain 2 score: 15.1 bits; conditional E-value: 2.1e-05 Beta-prop_DCAF4 230 savtsvqllqeeqlllaadmaGkiklwd.lratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahl 307 v sv +++++++ iklw+ l k q eGh + +++ + n + ++v++G d ++w l++++l FUN_001654-T1 106 KDVLSVAFSADNRQIVSGSRDKSIKLWNtLGVCKYTIQDEGHSDWVSCVRFSPNSSNPIIVSAGWDKLVKVWNLTNCRL 184 568899999999*****999*******857899*9***************************************99987 PP == domain 3 score: 1.9 bits; conditional E-value: 0.21 Beta-prop_DCAF4 270 hvneyaylplhvneeeGllvav.Gqdcytriwslkdahllrti 311 h ++ yl + + +G l+a G+d + +w l++++ l t+ FUN_001654-T1 188 HIGHQGYLNVVTVSPDGSLCASgGKDGMAMLWDLNEGKHLYTL 230 5556667777666666666654268999999999999888876 PP == domain 4 score: -1.4 bits; conditional E-value: 2.2 Beta-prop_DCAF4 241 eqlllaadmaGkiklwdlratkcv 264 +++ l+a + +ik+wdl + v FUN_001654-T1 244 NRYWLCAAVGPTIKIWDLEGKSLV 267 566677788889*****9877666 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.014 7.7 51 95 .. 7 52 .. 2 72 .. 0.79 2 ? 3.0 0.0 0.13 69 52 125 .. 56 123 .. 47 135 .. 0.72 3 ? 1.6 0.0 0.34 1.8e+02 57 91 .. 146 181 .. 100 192 .. 0.64 4 ? 6.1 0.0 0.014 7.6 58 90 .. 191 223 .. 174 232 .. 0.84 5 ? 5.3 0.0 0.025 14 62 137 .. 236 313 .. 225 316 .. 0.65 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.014 Beta-prop_HPS5 51 llqlltakegaistvaisp.dedlvavatsrglvvvvelnierkqk 95 l+ +l ++g ++++a +p d d + ++++ +++v++l+ ++++ FUN_001654-T1 7 LRGTLKGHDGWVTQIATNPqDPDKILSGSRDKKLIVWNLTRDETNY 52 66789999***********8899****************9765544 PP == domain 2 score: 3.0 bits; conditional E-value: 0.13 Beta-prop_HPS5 52 lqlltakegaistvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrvyiG 125 ++ lt ++ +s v +s+d ++ +++++ + +++ln+ +r + + v +++ +++ +++ +G FUN_001654-T1 56 YRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNA--GVTTRRF----VGHTKDVLSVAFSADNRQIVSG 123 6789999999***************************93..2222222....2223345555555555555555 PP == domain 3 score: 1.6 bits; conditional E-value: 0.34 Beta-prop_HPS5 57 akegaistvaisp..dedlvavatsrglvvvvelnie 91 ++ +s+v +sp ++ ++ a+++ lv v++l+ + FUN_001654-T1 146 GHSDWVSCVRFSPnsSNPIIVSAGWDKLVKVWNLT-N 181 34456999999997334456668999999999997.3 PP == domain 4 score: 6.1 bits; conditional E-value: 0.014 Beta-prop_HPS5 58 kegaistvaispdedlvavatsrglvvvvelni 90 ++g v++spd l a ++++g+ ++++ln FUN_001654-T1 191 HQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNE 223 5789999************************94 PP == domain 5 score: 5.3 bits; conditional E-value: 0.025 Beta-prop_HPS5 62 istvaispdedlvavatsrglvvvvelnier...kqkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsvtkls 137 i +++sp+ ++ a + +++l+ ++ + + + + + ++L+W+++++++++G + + v +++ FUN_001654-T1 236 INSLCFSPNRYWLCAAV-GPTIKIWDLEGKSlvdELTLDVISMGGKPPSADCMSLAWSADGQTLFAGYTDNLIRVWHVT 313 56677777777776554.45677888875331102222223333333455999**************999888888775 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.1 0.0047 2.5 267 368 .. 54 150 .. 35 159 .. 0.74 2 ! 11.0 0.3 0.00033 0.17 74 133 .. 165 223 .. 150 229 .. 0.88 3 ! 6.3 0.0 0.0086 4.6 103 134 .. 284 315 .. 275 317 .] 0.88 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0047 Beta-prop_IFT140_1st 267 vlkvKLsgktgkeadiiwaekglLita.tgesvirlwdlerddnyvLsldeklgfekgEaincvsyckakgiLaaGtnkGrvalwkkva 354 v L+g++ d+++ +g ++ + + ++++rlwdl+ + + +g ++ + +v++++ + + +G + lw++ FUN_001654-T1 54 VAYRALTGHNHFVSDVVMSSDGQFALSgSWDATLRLWDLNAGV----TTRRFVG--HTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLG 136 5555677777777777777666665542668999999998763....3333333..45579999**999999999999999****9999 PP Beta-prop_IFT140_1st 355 esssskkkegkekW 368 + + ++eg++ W FUN_001654-T1 137 VCKYTIQDEGHSDW 150 99899999999999 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00033 Beta-prop_IFT140_1st 74 ilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWkldq 133 i+ gw++ v v+n ++ +l++ + h+ ++v++ s gs +sg k G+ ++W l++ FUN_001654-T1 165 IVSAGWDK-LVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNE 223 56789987.599********************************************8865 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0086 Beta-prop_IFT140_1st 103 aeitvlewssngsrLvsgdksGvlvvWkldqr 134 a+ + l+ws+ g++L +g + ++ vW++ + FUN_001654-T1 284 ADCMSLAWSADGQTLFAGYTDNLIRVWHVTRV 315 677889*********************98765 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.1 0.0089 4.8 122 153 .. 104 136 .. 72 156 .. 0.86 2 ? 3.3 0.0 0.09 48 256 324 .. 145 213 .. 139 214 .. 0.70 3 ? 1.8 0.0 0.26 1.4e+02 61 114 .. 172 225 .. 162 233 .. 0.62 4 ! 8.7 0.0 0.0021 1.1 12 68 .. 246 312 .. 235 315 .. 0.80 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0089 Beta-prop_WDR19_1st 122 HskkItcgawskenl.LalgseDktltisnaeG 153 H+k +++ a+s++n ++ gs Dk++ + n+ G FUN_001654-T1 104 HTKDVLSVAFSADNRqIVSGSRDKSIKLWNTLG 136 ***********998638889********99877 PP == domain 2 score: 3.3 bits; conditional E-value: 0.09 Beta-prop_WDR19_1st 256 knhkdslsdialseslkk..vascg.dntvkihelsdlkevkeiieldeeekelekvewseDGqllavatks 324 + h+d +s++ +s++ ++ ++s+g d+ vk+ +l++++ ++ i +++ l+ v++s DG+l a k+ FUN_001654-T1 145 EGHSDWVSCVRFSPNSSNpiIVSAGwDKLVKVWNLTNCRLKTNHIG---HQGYLNVVTVSPDGSLCASGGKD 213 5688888999888777661144455577788888888876666555...45779999******998876665 PP == domain 3 score: 1.8 bits; conditional E-value: 0.26 Beta-prop_WDR19_1st 61 slvllwdantkktskldtglkdkltfllWskkspiLavGtskGnlllYnkktsk 114 +lv +w++++ + ++ +g + l++++ s ++++ a G + G +l++ ++ k FUN_001654-T1 172 KLVKVWNLTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGK 225 455666666666666666666666666666666666666666666666655555 PP == domain 4 score: 8.7 bits; conditional E-value: 0.0021 Beta-prop_WDR19_1st 12 ylavagknkvvkiydrqGe.lvdeiklk..........gkctaleWdkdgdlLaiiqeksslvllwda 68 y +a ++ki+d +G+ lvde++l+ c++l+W++dg++L + + +l+ +w++ FUN_001654-T1 246 YWLCAAVGPTIKIWDLEGKsLVDELTLDvismggkppsADCMSLAWSADGQTLFAGYT-DNLIRVWHV 312 555666677899***9998357999998888888888789************977665.567777776 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.089 47 69 129 .. 66 123 .. 54 159 .. 0.78 2 ! 6.9 0.0 0.0068 3.6 53 105 .. 179 231 .. 176 238 .. 0.87 3 ? 5.9 0.0 0.014 7.5 71 97 .. 288 314 .. 280 316 .. 0.92 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.089 Beta-prop_VPS8 69 VsalafnadstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikFtddptlalvs 129 Vs + +++d++ l G + ++++wDl+ g + r+ + + + vl + F d++ ++ FUN_001654-T1 66 VSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRF---VGHTKDVLSVAFSADNRQIVSG 123 777888888888888888899999999999866654...4455568888888887766654 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0068 Beta-prop_VPS8 53 LklclgstakgaeqgaVsalafnadstrllaGyarGqilmwDlsngkllrtis 105 L c +t++ +qg ++++ d++ + G ++G ++wDl++gk l t++ FUN_001654-T1 179 LTNCRLKTNHIGHQGYLNVVTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLE 231 556666777788999999*****************************998875 PP == domain 3 score: 5.9 bits; conditional E-value: 0.014 Beta-prop_VPS8 71 alafnadstrllaGyarGqilmwDlsn 97 +la +ad+++l aGy + i++w +++ FUN_001654-T1 288 SLAWSADGQTLFAGYTDNLIRVWHVTR 314 8999*******************9986 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 1.6 0.00058 0.31 60 194 .. 4 143 .. 1 188 [. 0.77 2 ? 5.1 0.3 0.028 15 68 218 .. 145 297 .. 139 315 .. 0.66 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00058 Beta-prop_WDR35_TULP_N 60 nlsmnqtlegHsgavqvvaWNek.ykkLtssDenGliivWmlykgswveemin...nrnksvvkdlkWssdgqkicivyedGavivG 142 l++ tl+gH+g v+ +a N + k+ s ++ +ivW l++++ + ++ +v+d+ ssdgq d ++ + FUN_001654-T1 4 GLTLRGTLKGHDGWVTQIATNPQdPDKILSGSRDKKLIVWNLTRDETNYGVAYralTGHNHFVSDVVMSSDGQFALSGSWDATLRLW 90 578889**************9762689999999999******998754444331113467899999999999998888889888664 PP Beta-prop_WDR35_TULP_N 143 ....svdGnrlwgkelkklklakvewspdgklllfglkegevhvydsegnflsklk 194 v r g+ ++ +v++s+d+++++ g+++ ++++++ g +++ FUN_001654-T1 91 dlnaGVTTRRFVGHTK---DVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIQ 143 1111566666666544...5789999999999999999999999999887665554 PP == domain 2 score: 5.1 bits; conditional E-value: 0.028 Beta-prop_WDR35_TULP_N 68 egHsgavqvvaW..NekykkLtssDenGliivWmlykgswveeminnrnksvvkdlkWssdgqkicivyedGavivGs.vdGnrlwg 151 egHs+ v++v++ N+++ + s+ + l+ vW l++ + + i ++ v+ + s+dg+ + +dG+ ++ +G++l++ FUN_001654-T1 145 EGHSDWVSCVRFspNSSNPIIVSAGWDKLVKVWNLTNCRLKTNHIGHQGYLNVV--TVSPDGSLCASGGKDGMAMLWDlNEGKHLYT 229 678888888776446666667888888888888888888888877776655554..4467888877888888777654157888888 PP Beta-prop_WDR35_TULP_N 152 kelkklklakvewspdgklllfglkegevhvydsegnf.lsklklkclek..vekelkivgiewykgkeg 218 e + + ++++sp+ ++ l + ++++d eg+ + +l+l +++ + +++ +++ w ++ ++ FUN_001654-T1 230 LEGGD-IINSLCFSPN-RYWLCAAVGPTIKIWDLEGKSlVDELTLDVISMggKPPSADCMSLAWSADGQT 297 88765.6888888886.45566666778888888887524566665554311445667777777765554 PP >> PROPPIN PROPPIN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.079 42 165 250 .. 9 96 .. 2 107 .. 0.69 2 ! 12.0 0.0 0.00022 0.12 167 247 .. 188 262 .. 105 269 .. 0.84 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.079 PROPPIN 165 ctiaahegtlaaitfnasg.sklasasekgtvi.rvfsvpdgqklyefrrgmkryvtisslvfsmdsqflcassntetvhifkleqvt 250 t+ h+g ++ i+ n k+ s s +i ++ + + +r + +s +v+s d qf + s t+ ++ l+ FUN_001654-T1 9 GTLKGHDGWVTQIATNPQDpDKILSGSRDKKLIvWNLTRDETNYGVAYRALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGV 96 577889999999988865426777777655544033333334444455655556677899**************99999999997643 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00022 PROPPIN 167 iaahegtlaaitfnasgsklasasekgtvirvfsvpdgqklyefrrgmkryvtisslvfsmdsqflcassntetvhifkle 247 h+g l +t+ gs as + g ++ + +g++ly + g i sl fs + +lca+ t++i+ le FUN_001654-T1 188 HIGHQGYLNVVTVSPDGSLCASGGKDGMA-MLWDLNEGKHLYTLEGGD----IINSLCFSPNRYWLCAAV-GPTIKIWDLE 262 4579**************99999887765.689**********99885....79*************986.5688888887 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.081 43 61 90 .. 104 132 .. 59 138 .. 0.62 2 ? 4.2 0.0 0.06 32 61 103 .. 104 142 .. 93 153 .. 0.76 3 ? 3.7 0.0 0.084 45 61 94 .. 147 181 .. 145 194 .. 0.81 4 ? 3.3 0.0 0.11 60 281 311 .. 206 236 .. 196 252 .. 0.79 5 ? 0.7 0.0 0.68 3.6e+02 65 105 .. 236 274 .. 233 315 .. 0.62 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.081 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlklt 90 H+k++ ++aF+ ++ ++s s Dk++kl FUN_001654-T1 104 HTKDVLSVAFSAD-NRQIVSGSRDKSIKLW 132 6666666666665.4445566666666664 PP == domain 2 score: 4.2 bits; conditional E-value: 0.06 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsntvvqtYet 103 H+k++ ++aF+ ++ ++s s Dk++kl + l v++Y++ FUN_001654-T1 104 HTKDVLSVAFSAD-NRQIVSGSRDKSIKLWNTL---GVCKYTI 142 9*********999.666789********97654...3555555 PP == domain 3 score: 3.7 bits; conditional E-value: 0.084 WD40_RFWD3 61 HskaiRdlaFnse.qdslllsaslDktlkltslls 94 Hs+ + + F+++ ++ +++sa+ Dk +k+ +l++ FUN_001654-T1 147 HSDWVSCVRFSPNsSNPIIVSAGWDKLVKVWNLTN 181 777777889996515689************99875 PP == domain 4 score: 3.3 bits; conditional E-value: 0.11 WD40_RFWD3 281 vaagdeasksvllWdassgkqlqklsvsspv 311 ++a+ + ++lWd + gk+l +l+ ++ + FUN_001654-T1 206 LCASGGKDGMAMLWDLNEGKHLYTLEGGDII 236 57888888899*************9876654 PP == domain 5 score: 0.7 bits; conditional E-value: 0.68 WD40_RFWD3 65 iRdlaFnseqdslllsaslDktlkltsllsntvvqtYetds 105 i +l+F+++ + l a++ t+k+ +l+ +++v + ++d FUN_001654-T1 236 INSLCFSPN--RYWLCAAVGPTIKIWDLEGKSLVDELTLDV 274 566777776..677888888899999888888888777653 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.1 0.0017 0.93 26 121 .. 34 134 .. 19 168 .. 0.60 2 ? 6.1 0.0 0.016 8.5 56 132 .. 198 272 .. 156 312 .. 0.83 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0017 Beta-prop_ACSF4 26 gSHsgkivcvdletgeviw.....eielpdriEssacvskdgklvvvGcydgklycldlatgeilwkfk.tgdaiKsspvidsesglvvvgsyd 113 gS ++k+++ +l +e+ + ++ ++ + s++++s+dg++ + G+ d +l dl+ g + +f + + s + + ++ +v gs d FUN_001654-T1 34 GSRDKKLIVWNLTRDETNYgvayrALTGHNHFVSDVVMSSDGQFALSGSWDATLRLWDLNAGVTTRRFVgHTKDVLSVAFSAD-NRQIVSGSRD 126 44444444444444443331111122233355566677777777777777777777777777777777644455666555544.4455677777 PP Beta-prop_ACSF4 114 knlyaldv 121 k++ +++ FUN_001654-T1 127 KSIKLWNT 134 77776665 PP == domain 2 score: 6.1 bits; conditional E-value: 0.016 Beta-prop_ACSF4 56 acvskdgklvvvGcydgklycldlatgeilwkfktgdaiKsspvidsesglvvvgsydknlyaldvesgklvwklkl 132 ++vs+dg+l G+ dg + dl++g+ l++ + gd i s + +++ ++++ + + +d+e ++lv +l+l FUN_001654-T1 198 VTVSPDGSLCASGGKDGMAMLWDLNEGKHLYTLEGGDIINSLCFS-PNR-YWLCAAVGPTIKIWDLEGKSLVDELTL 272 578999999999***************************998874.555.556999999999999998888866544 PP >> Cytochrom_D1 Cytochrome D1 heme domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.3 0.00073 0.39 39 95 .. 67 124 .. 48 127 .. 0.85 2 ? 0.4 0.0 0.5 2.7e+02 35 72 .. 233 269 .. 188 301 .. 0.62 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00073 Cytochrom_D1 39 isrvfssdgRyvyvigRDgkvtliDLwakk.ivaevkaGlnarsvavSqddryvivgn 95 +v ssdg +++ + D+++ l DL a + + v + sva S d+r ++ g+ FUN_001654-T1 67 SDVVMSSDGQFALSGSWDATLRLWDLNAGVtTRRFVGHTKDVLSVAFSADNRQIVSGS 124 457899*********************9984556688899**************9986 PP == domain 2 score: 0.4 bits; conditional E-value: 0.5 Cytochrom_D1 35 yalHisrvfssdgRyvyvigRDgkvtliDLwakkivae 72 +++ s fs+ +Ry + ++ ++++ DL k v e FUN_001654-T1 233 GDIINSLCFSP-NRYWLCAAVGPTIKIWDLEGKSLVDE 269 34445555666.56666666555666666555554444 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.0023 1.2 106 183 .. 63 140 .. 14 173 .. 0.73 2 ? 1.2 0.0 0.47 2.5e+02 136 175 .. 260 311 .. 198 315 .. 0.81 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0023 Beta-prop_NUP159_NUP214 106 gvsiralkpnpspeaellailtsngkLlladlkarslv...svlkenvssfdwsnkgkqlvvgladgtaqqlkpadgevka 183 + + ++++ + +++ + + + +L+l dl+a+ ++ ++++v s++ s+ ++q+v g++d++++ ++ g k FUN_001654-T1 63 NHFVSDVVMSSD--GQFALSGSWDATLRLWDLNAGVTTrrfVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT-LGVCKY 140 455666666666..5666666778999999999999888889999***********************998776.555555 PP == domain 2 score: 1.2 bits; conditional E-value: 0.47 Beta-prop_NUP159_NUP214 136 dlkarslv............svlkenvssfdwsnkgkqlvvgladgtaqqlk 175 dl+ +slv + ++++ s++ws+ g+ l++g +d+ + + + FUN_001654-T1 260 DLEGKSLVdeltldvismggKPPSADCMSLAWSADGQTLFAGYTDNLIRVWH 311 5555555555555555566666678899**************9999887655 PP >> DUF1416 Protein of unknown function (DUF1416) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.0005 0.26 24 70 .. 43 87 .. 30 113 .. 0.77 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.0005 DUF1416 24 GkvlkdgepvggayvRLLdssgeftaevvtsaeGefrffaapGtW..tv 70 + ++d++ g ay R L +++ f+++vv s++G+f a G+W t+ FUN_001654-T1 43 WNLTRDETNYGVAY-RALTGHNHFVSDVVMSSDGQF---ALSGSWdaTL 87 56677777777787.889999*************96...7788884444 PP >> PD40 WD40-like Beta Propeller Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 3.6 1.9e+03 24 35 .. 70 84 .. 69 90 .. 0.76 2 ? -0.8 0.0 4.5 2.4e+03 15 24 .. 112 121 .. 109 121 .. 0.85 3 ? 1.0 0.0 1.2 6.4e+02 15 21 .. 199 205 .. 198 206 .. 0.86 4 ? 4.6 0.0 0.088 47 15 23 .. 290 298 .. 287 299 .. 0.88 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.6 PD40 24 aFsSdrd...sGkpd 35 + sSd++ sG++d FUN_001654-T1 70 VMSSDGQfalSGSWD 84 578999999999998 PP == domain 2 score: -0.8 bits; conditional E-value: 4.5 PD40 15 sfSPDGkrla 24 +fS D ++++ FUN_001654-T1 112 AFSADNRQIV 121 8****99996 PP == domain 3 score: 1.0 bits; conditional E-value: 1.2 PD40 15 sfSPDGk 21 ++SPDG+ FUN_001654-T1 199 TVSPDGS 205 79****6 PP == domain 4 score: 4.6 bits; conditional E-value: 0.088 PD40 15 sfSPDGkrl 23 ++S DG++l FUN_001654-T1 290 AWSADGQTL 298 8******98 PP >> Beta-prop_pof12 F-box protein pof12 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.5 0.0015 0.78 287 363 .. 57 130 .. 31 160 .. 0.70 2 ? -0.7 0.0 1.5 7.8e+02 313 325 .. 252 264 .. 249 273 .. 0.82 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0015 Beta-prop_pof12 287 qrLWGHTSsvsgvqvsdrGk.AvSvSsrGdelRvWeLEglvsslasrrrllkgeksvrvspekkksseeesekkeele 363 + L GH vs v +s+ G+ A+S S lR+W+L +v++ + +k+ sv s+++++ + +++++++ FUN_001654-T1 57 RALTGHNHFVSDVVMSSDGQfALSGS-WDATLRLWDLNAGVTTRRFVG-HTKDVLSVAFSADNRQI--VSGSRDKSIK 130 5689***************9566655.5568*********99733333.45677889888888865..2223333333 PP == domain 2 score: -0.7 bits; conditional E-value: 1.5 Beta-prop_pof12 313 rGdelRvWeLEgl 325 G +++W+LEg FUN_001654-T1 252 VGPTIKIWDLEGK 264 5788*******86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 527 (0.0206303); expected 510.9 (0.02) Passed bias filter: 486 (0.0190252); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 49 (0.00191818); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 48 [number of targets reported over threshold] # CPU time: 0.54u 0.37s 00:00:00.91 Elapsed: 00:00:00.46 # Mc/sec: 2781.93 // Query: FUN_001655-T1 [L=1225] Description: FUN_001655 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-185 616.6 0.0 3.2e-185 616.1 0.0 1.2 1 COPI_C Coatomer (COPI) alpha subunit C-te 1.5e-71 241.3 0.1 3e-71 240.3 0.1 1.5 1 B-prop_COPA_B_2nd COPA/B second beta-propeller 3.6e-58 197.6 8.9 3e-30 106.0 1.2 4.7 4 Beta-prop_WDR5 WDR5 beta-propeller domain 4.3e-52 177.0 3.2 1.1e-31 110.4 0.1 3.0 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 2.2e-51 170.6 17.3 2.4e-09 37.8 0.4 9.1 8 WD40 WD domain, G-beta repeat 1.1e-50 172.8 2.3 2.7e-20 73.1 0.1 4.6 4 WD40_Prp19 Prp19 WD40 domain 2.1e-47 161.9 5.9 1.8e-16 60.5 0.1 5.2 4 Beta-prop_THOC3 THOC3 beta-propeller domain 3.1e-35 122.3 0.5 1.4e-11 44.6 0.0 5.8 6 WD40_WDHD1_1st WDHD1 first WD40 domain 1.7e-32 113.2 0.1 2.2e-12 47.1 0.0 3.6 3 WDR55 WDR55 2.1e-26 93.4 6.4 1.2e-16 61.3 0.2 4.0 3 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 3.8e-26 92.7 3.4 1.1e-15 58.2 0.1 4.3 5 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 1.1e-25 90.9 5.8 1.5e-08 34.7 0.2 3.9 4 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 7.5e-22 78.4 5.7 1.2e-06 28.6 0.1 6.1 4 Beta-prop_EML_2 Echinoderm microtubule-associated 8.6e-22 78.3 0.5 3e-07 30.6 0.0 6.3 7 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 7.2e-21 75.0 0.1 5.7e-07 29.3 0.0 3.4 4 WD40_Gbeta G protein beta WD-40 repeat protei 1.4e-20 74.3 0.1 3.3e-20 73.0 0.1 1.6 1 TPR_COPA_B COPA/B TPR domain 1.6e-20 73.9 5.1 2.8e-09 36.9 0.6 4.0 3 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 1.1e-19 71.3 3.4 0.0003 20.6 0.0 5.2 5 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 6.8e-19 68.6 2.4 2e-06 27.6 0.1 4.8 5 EIF3I EIF3I 8.3e-18 64.9 4.7 3.1e-09 36.8 0.4 3.2 2 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 1.2e-16 61.5 5.3 1.1e-05 25.5 0.1 4.4 4 Beta-prop_EML Echinoderm microtubule-associated 3.1e-16 59.6 6.7 0.018 15.5 0.0 6.1 5 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 4.2e-14 53.0 5.7 0.00015 21.7 0.3 5.9 5 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 5.5e-14 52.8 2.3 9.3e-05 22.5 0.0 4.0 3 Beta-prop_EIPR1 EIPR1 beta-propeller 4.7e-12 46.3 6.3 0.0016 18.3 0.1 4.4 4 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 4e-11 43.5 2.1 2.2e-06 28.3 0.0 5.4 5 ANAPC4_WD40 Anaphase-promoting complex subunit 8.2e-10 38.6 0.2 6.9e-05 22.4 0.2 3.3 2 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 2.9e-09 37.2 0.7 0.00091 19.1 0.1 4.5 4 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 8e-09 35.3 0.5 2.9e-05 23.6 0.3 2.3 2 Beta-prop_SCAP SCAP Beta-propeller 2.4e-08 33.7 4.5 0.00011 21.6 0.5 4.0 4 Beta-prop_WDR41 WDR41 2.3e-07 30.8 5.6 0.062 12.9 0.8 4.0 4 Beta-prop_Aladin Aladin seven-bladed propeller 9.2e-07 28.5 1.2 0.18 11.1 0.0 4.4 4 Beta-prop_SPT8 SPT8 beta propeller 9.8e-07 28.3 4.5 0.054 12.7 0.0 3.6 3 Beta-prop_IFT140_1st IFT140 first beta-propeller 1.3e-06 28.0 0.8 0.047 13.0 0.0 3.3 3 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 1.7e-05 24.4 0.4 0.12 11.7 0.1 3.3 4 NBCH_WD40 Neurobeachin beta propeller domain 5.6e-05 22.7 0.1 0.26 10.6 0.0 3.9 4 Beta-prop_IFT122_1st IFT122 first beta-propeller 0.0015 18.1 1.7 0.68 9.4 0.0 3.5 3 Beta-prop_WDR19_1st WDR19 first beta-propeller 0.002 18.1 14.5 0.36 10.7 0.4 6.3 8 Beta-prop_RIG_2nd RIG second beta-propeller 0.0056 16.4 0.0 3.4 7.3 0.0 3.3 3 Beta-prop_HPS5 HPS5 beta-propeller ------ inclusion threshold ------ 0.012 14.8 5.4 2.2 7.3 0.0 4.0 4 Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-prope 0.069 12.7 0.5 14 5.1 0.0 2.7 2 WDR90_beta-prop_4th WDR90, 4th beta-propeller 0.083 13.0 0.2 0.36 10.9 0.0 2.1 2 Aa-Ago_N Ago, N-terminal domain 0.18 12.2 0.0 0.88 9.9 0.0 2.2 1 TPR_IFT80_172 IFT80/172/WDR35/WDR19 TPR domain 0.21 12.9 0.3 20 6.7 0.0 3.9 3 TPR_14 Tetratricopeptide repeat 0.28 10.5 2.3 12 5.1 0.0 2.8 3 Beta-prop_IP5PC_F IP5P C-F beta-propeller 0.36 10.2 2.6 11 5.2 0.3 3.1 3 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 Domain annotation for each model (and alignments): >> COPI_C Coatomer (COPI) alpha subunit C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 616.1 0.0 5.7e-188 3.2e-185 1 405 [] 818 1225 .] 818 1225 .] 0.96 Alignments for each domain: == domain 1 score: 616.1 bits; conditional E-value: 5.7e-188 COPI_C 1 kgffegalaskakasaaav.eedeeeaagegWGddedldleeakkekeaeaeeeeeeddeeegGWdv..edlelppeleveaaasaaksevfva 91 k+ffega+a+ka ++aaa+ +d++e a egWG+d+dl ++e+ + ++ a+ + +dee+gGWdv edl lp++l+v a+++ ++++fv+ FUN_001655-T1 818 KTFFEGAMAAKAGGGAAAMaVTDMDEGAAEGWGEDADLVIDEE-GGFDDGADGDSLGGDEEGGGWDVgdEDLVLPADLDVGLASGTGDEGYFVP 910 78********99999875515677799***************4.4444444444457889********************************** PP COPI_C 92 PtkgvpvsqiWtnksslavdhvaaGsfetAmrlLndqvGvvnfePlkslFldlyaasrtslealpslpslllalernwkeaaaknglPalvlkl 185 P kg+++sq+W+n+s+lavdhv+aGsfe+AmrlL+dqvGvv f+P+k+lF+ ++ + rt+l a+p p+ll +++rnw++a+ak glPa+ lkl FUN_001655-T1 911 PVKGTSQSQVWCNNSQLAVDHVSAGSFESAMRLLHDQVGVVVFNPYKPLFMLAFGRGRTALPATPGGPPLLGHPHRNWRDAGAKGGLPAVGLKL 1004 ********************************************************************************************** PP COPI_C 186 sqleerLkaaYkltteGkfseavekfrsillsipllvVdskqevdevkeLikicreYvvgLrmElkRkelkke.lddqkraaElaAYfthcnlq 278 ++l++rL++aY+ltt Gkf+eav+k++sills++llvVdskqev+e+++L+ icreY+vgL+mElkRkel+k+ l++qkr++E+aAYfthcnlq FUN_001655-T1 1005 NTLVQRLQSAYQLTTGGKFQEAVQKLHSILLSVTLLVVDSKQEVSEAQQLLGICREYIVGLQMELKRKELPKStLEEQKRICEMAAYFTHCNLQ 1098 ********************************************************************************************** PP COPI_C 279 pvHliLaLrsAlnlffKlknfktaasfarrLLelgpkeevaqqarkvlqaceknptdevelnYderNPFvvcaatfvPiYrGkkevkcplcgas 372 pvH+iL+Lr+A+nlffKlknfktaasfarrLLelgp+++va+q+rk+lqac+knptd+++l+Yd++NPF+vca +++P+YrGk+++kcplc+as FUN_001655-T1 1099 PVHQILTLRTAVNLFFKLKNFKTAASFARRLLELGPRPDVATQIRKILQACDKNPTDAHNLQYDQHNPFTVCAVSYKPLYRGKPQEKCPLCQAS 1192 ********************************************************************************************** PP COPI_C 373 yvpelkgkvckvcevaeiGkdasGLrisplqfr 405 y+pe+kg+vc+vc+vae+Gkd++GLr+splqfr FUN_001655-T1 1193 YCPEYKGTVCNVCKVAEVGKDTVGLRVSPLQFR 1225 *******************************97 PP >> B-prop_COPA_B_2nd COPA/B second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 240.3 0.1 5.4e-74 3e-71 3 248 .] 342 585 .. 340 585 .. 0.95 Alignments for each domain: == domain 1 score: 240.3 bits; conditional E-value: 5.4e-74 B-prop_COPA_B_2nd 3 evrsanlkkkekdgellslslkelgsvevypqslshnpngrfvlv......cgdgeyeiyt........alalrnkaygkgldfvwvarnrf 80 +r++++ ++ ++++ +++++++s +++ s+s+np++++vl+ ++ ye+ + ++++ ++ +gl++vwvarnrf FUN_001655-T1 342 YLRMYEFGTS---KDVPVMQFRRNSSR-TPVYSMSFNPAENCVLLctnasnPENCVYELHAvpkeidssNPEVSEGKRASGLTAVWVARNRF 429 68999**999...9*******998765.569**************8886666666666666*******999********************* PP B-prop_COPA_B_2nd 81 AvleksktvkifknfkekktksikleysvekifgggtGslLgvksessvilYDwqqkklvreidvkavkyVvWsddgelvallskdtvyiln 172 Avl++++t+ i kn+k+++tk+++++ ++ if++gtGslL+++++s v+l+D+qqk++++ ++v++v+yVvWs d+++vall+k+ v i+n FUN_001655-T1 430 AVLDRTHTLLI-KNLKNEVTKKVQTP-PCDMIFYAGTGSLLLRDTDS-VTLFDVQQKRTLATVKVNKVRYVVWSADMSYVALLGKHVVAICN 518 ***********.**************.5*******************.******************************************** PP B-prop_COPA_B_2nd 173 knleaveegvedafevlheiservksgaWved.vliYttsnhlkY.lvnGevgiiktldktlyllgylgkenrvylld 248 ++le ++++he ++rvksgaW e+ v++Yttsnh+kY l+nG++gii+tld ++y+++++g ++vy+ld FUN_001655-T1 519 RKLE--------CLCTIHE-NIRVKSGAWEENgVFVYTTSNHIKYaLTNGDHGIIRTLDLPIYITRVKG--SSVYCLD 585 ****........*******.*************************************************..******8 PP >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 106.0 1.2 5.5e-33 3e-30 4 121 .. 49 166 .. 48 177 .. 0.96 2 ! 79.1 0.2 8.4e-25 4.7e-22 33 134 .. 192 295 .. 185 324 .. 0.88 3 ? 0.0 0.0 1 5.7e+02 156 195 .. 343 385 .. 337 398 .. 0.66 4 ? -0.6 0.0 1.6 9e+02 199 222 .. 475 498 .. 433 550 .. 0.65 Alignments for each domain: == domain 1 score: 106.0 bits; conditional E-value: 5.5e-33 Beta-prop_WDR5 4 ghkkavssvkfspdgkllasasaDktikiwdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaF 98 +h +v ++f+ + l+ s + D ikiw+ ++ k+ tl gh + i + + ++ +++saSDD+t+riw+ ++++++ +l+gH++yv+c +F FUN_001655-T1 49 EHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQF 143 6999999**************************************************************************************** PP Beta-prop_WDR5 99 npkgnllvSGsfDetvrlWdvrt 121 +p+++l+vS+s D+tvr+Wd++ FUN_001655-T1 144 HPSEDLVVSASLDQTVRVWDISG 166 ********************975 PP == domain 2 score: 79.1 bits; conditional E-value: 8.4e-25 Beta-prop_WDR5 33 wdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgk..llktlkgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkcl 125 + ++ ++++legh +G++ va+ + l++s++DD++v++w+++ +k + t +gH n v cv F+p+++l++S s D+++r+Wd+++ + + FUN_001655-T1 192 FGQSDAIVKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGV 286 556677789*************************************98866899***************************************** PP Beta-prop_WDR5 126 ktlpaHsdp 134 +t+ +d FUN_001655-T1 287 QTFRREHDR 295 *99877665 PP == domain 3 score: 0.0 bits; conditional E-value: 1 Beta-prop_WDR5 156 iriwdtetgqclktlv...eddnppvsfvkFspngkyiLastl 195 +r+++ t + + + +++++pv +++F p ++++L +t FUN_001655-T1 343 LRMYEFGTSKDVPVMQfrrNSSRTPVYSMSFNPAENCVLLCTN 385 5566655555555543111235558888888888888888775 PP == domain 4 score: -0.6 bits; conditional E-value: 1.6 Beta-prop_WDR5 199 irLwdyekekvvktYkghknekyc 222 + L+d+++++++ t k +k + + FUN_001655-T1 475 VTLFDVQQKRTLATVKVNKVRYVV 498 223333333322222222222222 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.4 0.1 2e-34 1.1e-31 24 184 .] 4 164 .. 1 164 [. 0.98 2 ! 66.0 0.1 8.7e-21 4.8e-18 52 183 .. 188 320 .. 184 321 .. 0.89 3 ? -2.1 0.0 6.6 3.7e+03 9 36 .. 473 498 .. 467 510 .. 0.52 Alignments for each domain: == domain 1 score: 110.4 bits; conditional E-value: 2e-34 Beta-prop_WDR3_1st 24 tlegeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkd 114 ++e+++++v+ +a++p++ + + ++g i+lwd++ +l f+ H + v ++f++++ +sG+ D +i +w+ ++++lf+L gH d FUN_001655-T1 4 KFETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLD 94 6788999************************************************************************************ PP Beta-prop_WDR3_1st 115 qvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtgssdselrvwki 184 + + f +e +++s+S+D++i++W+ +++ c l+gh++ v++ +++++e+l+v++s d+++rvw+i FUN_001655-T1 95 YIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164 ********************************************************************98 PP == domain 2 score: 66.0 bits; conditional E-value: 8.7e-21 Beta-prop_WDR3_1st 52 sirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvaea..glfrLkgHkdqvtsvafleekkvlvssSkDtliklW 140 + +l+ +++ ++ +++gH + v+ +af+++ ++sG+ D ++ +w + + + + + +gH ++v v f +++++++s S+D+ i++W FUN_001655-T1 188 HTELFGQSDAIVKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVW 278 5678888889999**********************************9987762256799******************************* PP Beta-prop_WDR3_1st 141 dletqhcvktlvghrsevwslalskdekllvtgssdselrvwk 183 d++++ v+t+ ++ + w a ++ +l +++++ds + v+k FUN_001655-T1 279 DMSKRTGVQTFRREHDRFWVAAAHPTLNL-FAAGHDSGMIVFK 320 **********************9998665.5555788777776 PP == domain 3 score: -2.1 bits; conditional E-value: 6.6 Beta-prop_WDR3_1st 9 ekvlvWdlkkgekvatlegeksevtala 36 ++v ++d+++++++at++ + +v ++ FUN_001655-T1 473 DSVTLFDVQQKRTLATVKVN--KVRYVV 498 44555555555555554433..233333 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 6e-05 0.033 7 39 .] 5 37 .. 1 37 [. 0.85 2 ! 26.9 0.0 1.2e-08 6.7e-06 3 39 .] 43 79 .. 41 79 .. 0.93 3 ! 28.6 0.1 3.4e-09 1.9e-06 2 39 .] 84 121 .. 83 121 .. 0.96 4 ! 37.8 0.4 4.2e-12 2.4e-09 2 39 .] 126 163 .. 125 163 .. 0.95 5 ! 32.5 0.0 2.1e-10 1.1e-07 4 38 .. 200 234 .. 198 235 .. 0.95 6 ! 30.8 0.1 7.2e-10 4e-07 4 39 .] 244 279 .. 242 279 .. 0.95 7 ? -0.3 0.0 5.1 2.8e+03 9 35 .. 292 317 .. 285 319 .. 0.66 8 ? 1.4 0.0 1.4 7.8e+02 11 27 .. 365 381 .. 354 387 .. 0.73 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 6e-05 WD40 7 lkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++ ++ V ++af+p+ ++++++ ++g + lWd FUN_001655-T1 5 FETKSARVKGIAFHPTRPWVLASLHNGVIQLWD 37 5555556**************9999*******9 PP == domain 2 score: 26.9 bits; conditional E-value: 1.2e-08 WD40 3 llrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ll ++ H+++V+++ f+ + +l++sg+dD ++k+W+ FUN_001655-T1 43 LLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWN 79 677899**999*************************7 PP == domain 3 score: 28.6 bits; conditional E-value: 3.4e-09 WD40 2 kllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 k+l tl gH + +++ f++ ++++s+sdD t+++W+ FUN_001655-T1 84 KCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWN 121 8********999**999********************7 PP == domain 4 score: 37.8 bits; conditional E-value: 4.2e-12 WD40 2 kllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +++ +l+gH+ V++ f+p+ +l++s+s D tv++Wd FUN_001655-T1 126 TCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWD 163 6899999**888*************************9 PP == domain 5 score: 32.5 bits; conditional E-value: 2.1e-10 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklW 38 ++l+gH+ gV+ +af+p+ +l++sg+dD+ vklW FUN_001655-T1 200 KHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLW 234 589****999************************* PP == domain 6 score: 30.8 bits; conditional E-value: 7.2e-10 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 + t++gH ++V+++ f+p l++s s+D+++++Wd FUN_001655-T1 244 VDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWD 279 57899**999*************************9 PP == domain 7 score: -0.3 bits; conditional E-value: 5.1 WD40 9 gHtsgVtslafspdgsllasgsdDgtv 35 H + + a +p+ +l+a+g d g + FUN_001655-T1 292 EH-DRFWVAAAHPTLNLFAAGHDSGMI 317 56.344444569999***998856555 PP == domain 8 score: 1.4 bits; conditional E-value: 1.4 WD40 11 tsgVtslafspdgslla 27 +++V+s++f+p + ++ FUN_001655-T1 365 RTPVYSMSFNPAENCVL 381 345********999864 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 3.8e-06 0.0021 132 188 .. 6 62 .. 1 63 [. 0.80 2 ! 73.1 0.1 4.9e-23 2.7e-20 17 122 .. 61 166 .. 58 184 .. 0.94 3 ! 72.5 0.1 7.3e-23 4.1e-20 32 159 .. 190 317 .. 175 334 .. 0.90 4 ! 7.0 0.2 0.0068 3.8 199 279 .. 473 549 .. 465 551 .. 0.87 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 3.8e-06 WD40_Prp19 132 eeskeaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeN 188 e+++++++ ++fHP + + ++g++++WD + + + +++h g+v+ ++F N FUN_001655-T1 6 ETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTN 62 344567888999999999999999999999999999999999999999999998665 PP == domain 2 score: 73.1 bits; conditional E-value: 4.9e-23 WD40_Prp19 17 sdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgdylvsaskD 112 +++ l+++GG D ++ +++ +++k l tl gh + ++ fh++ ++sas+D+t+r+w+ ++++++ +l+ h++ v + ++hp++d++vsas D FUN_001655-T1 61 TNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLD 156 567799****************************************************************************************** PP WD40_Prp19 113 gtwalhdlet 122 +t+ ++d++ FUN_001655-T1 157 QTVRVWDISG 166 *******975 PP == domain 3 score: 72.5 bits; conditional E-value: 7.3e-23 WD40_Prp19 32 vlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeket..aatlkkhkaevtslsvhptgdylvsaskDgtwalhdletgkt 125 lf +++ v + l+gh + v+ vafhp+ ++vs+++D++v++w+ +++++ + t++ h ++v+++ +hp +++++s s+D+++ ++d+++ + FUN_001655-T1 190 ELFGQSDAIVKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKAweVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTG 285 678889999999***********************************9987612467*************************************** PP WD40_Prp19 126 llkvkdeeskeaitsaqfHPDGlllgtGtkdgtv 159 +++++ e+ +++ a+ HP +l+++G ++g++ FUN_001655-T1 286 VQTFRREH--DRFWVAAAHPTLNLFAAGHDSGMI 317 ***98765..589****************99887 PP == domain 4 score: 7.0 bits; conditional E-value: 0.0068 WD40_Prp19 199 gtvklWDLRklknfktleldeeskvnsvaFDksgqyLavagsdvrvyevkkweelatledhtaevtsvafgpdakslvsas 279 +v l+D ++++++t++++ kv+ v + +y a+ g++v + ++k e l+t+++ + +v+s a+ ++ +++++s FUN_001655-T1 473 DSVTLFDVQQKRTLATVKVN---KVRYVVWSADMSYVALLGKHVVAICNRKLECLCTIHE-NIRVKSGAWEENGVFVYTTS 549 5899********99999985...59**************999988777888999999986.55699**********99998 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.5 0.1 3.2e-19 1.8e-16 127 245 .. 7 125 .. 2 127 .. 0.95 2 ! 47.4 1.1 3.2e-15 1.8e-12 17 78 .. 108 166 .. 106 202 .. 0.85 3 ! 58.2 0.1 1.6e-18 8.9e-16 1 113 [. 206 318 .. 206 401 .. 0.91 4 ! 11.9 0.0 0.0002 0.11 69 152 .. 473 553 .. 464 594 .. 0.77 Alignments for each domain: == domain 1 score: 60.5 bits; conditional E-value: 3.2e-19 Beta-prop_THOC3 127 kfkkevnevafspdgkllllttgdgtvevlsypsleevktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvs 220 + + +v+ +af+p+ +l++ ++g +++++y ++ +++++ h + + ++f+ ++ ++++G+ D +++W++++ +cl tl ++ +r+ FUN_001655-T1 7 TKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTF 100 45678999************************************************************************************** PP Beta-prop_THOC3 221 FShdGkllAsasedktidiasvetg 245 F h+ ++ sas+d+ti+i++ ++ FUN_001655-T1 101 FHHEYPWIISASDDQTIRIWNWQSR 125 *********************9875 PP == domain 2 score: 47.4 bits; conditional E-value: 3.2e-15 Beta-prop_THOC3 17 LasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrt 78 + s+s+D+t+r+wn+++++++ l+gh+ V + +++p++ dl+++as D+tvr+Wd+ FUN_001655-T1 108 IISASDDQTIRIWNWQSRTCTC--VLTGHNHYVMCAQFHPSE-DLVVSASLDQTVRVWDISG 166 68**************998875..8***************85.9***************975 PP == domain 3 score: 58.2 bits; conditional E-value: 1.6e-18 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvktkgenin. 93 h++ v+ va+ ++ ++sg++D+ v++w +++sk + +++gh ++V+++ ++p + +l+ + s+Dk++r+Wd+ ++ ++t++ +++ + FUN_001655-T1 206 HDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKAWEVDTCRGHYNNVSCVMFHPRQ-ELILSNSEDKSIRVWDMSKRTGVQTFRREHDRFWv 298 78899******************************99999****************86.79************************998887752 PP Beta-prop_THOC3 94 lawspdGktiavgskddtvs 113 a +p + a+g+++ ++ FUN_001655-T1 299 AAAHPTLNLFAAGHDSGMIV 318 66788888888888776665 PP == domain 4 score: 11.9 bits; conditional E-value: 0.0002 Beta-prop_THOC3 69 ktvrlWdvrtgkstatvktkgeninlawspdGktiavgskddtvslidvrtgkvkkeekfkkevnevafspdgkllllttgdgt 152 +v l+dv++++++atvk ++ + ws d +++a k ++v ++ r+ ++ + + + +v++ a++++g ++++t+++ + FUN_001655-T1 473 DSVTLFDVQQKRTLATVKVNK-VRYVVWSADMSYVALLGK-HVVAIC-NRKLECLCTIHENIRVKSGAWEENGVFVYTTSNHIK 553 4799*************9865.67899*********9988.455555.6888888999999**********9998888876544 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 1.4e-07 7.8e-05 86 165 .. 9 88 .. 1 98 [. 0.92 2 ! 44.6 0.1 2.5e-14 1.4e-11 91 159 .. 98 166 .. 94 181 .. 0.89 3 ! 17.2 0.0 5.6e-06 0.0031 121 162 .. 200 241 .. 193 247 .. 0.89 4 ! 44.6 0.0 2.5e-14 1.4e-11 89 166 .. 210 289 .. 207 302 .. 0.93 5 ? 0.9 0.0 0.52 2.9e+02 248 286 .. 347 386 .. 327 389 .. 0.72 6 ? -1.4 0.0 2.7 1.5e+03 200 238 .. 473 507 .. 418 549 .. 0.67 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 1.4e-07 WD40_WDHD1_1st 86 tapvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvkt 165 +a v+ ia+++++ ++ a+ + i++ + + + +++h++pv+ ++++ ++ + +S + D ++kiW+ ++k+c+ t FUN_001655-T1 9 SARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFT 88 578999************************9999999***************************************9855 PP == domain 2 score: 44.6 bits; conditional E-value: 2.5e-14 WD40_WDHD1_1st 91 hialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdies 159 + ++++ +++++s+D ti++ + + + +++l+gh++ v++ +++p++ +++S+s D tv++Wdi+ FUN_001655-T1 98 TTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISG 166 55677788899********************************************************94 PP == domain 3 score: 17.2 bits; conditional E-value: 5.6e-06 WD40_WDHD1_1st 121 qktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskec 162 +++legh+ v +va++p++ +++S + D +vk+W +++++ FUN_001655-T1 200 KHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKA 241 579**********************************99876 PP == domain 4 score: 44.6 bits; conditional E-value: 2.5e-14 WD40_WDHD1_1st 89 vthialskdgkllaagseDftikvvsvedss..kqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktl 166 v+ +a++++ l+++g++D ++k+ ++ds+ ++ t++gh + v +v ++p++e++ S+s D ++++Wd+++++ v+t+ FUN_001655-T1 210 VNWVAFHPTMPLIVSGADDRQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTF 289 778999*********************9998557889************************************9999986 PP == domain 5 score: 0.9 bits; conditional E-value: 0.52 WD40_WDHD1_1st 248 vWdvatkelierv.khekklaitslaWnpkeneLaftDae 286 + ++++ + ++ ++++++++ s+++np en ++++ + FUN_001655-T1 347 EFGTSKDVPVMQFrRNSSRTPVYSMSFNPAENCVLLCTNA 386 455556666666624557899***********87777664 PP == domain 6 score: -1.4 bits; conditional E-value: 2.7 WD40_WDHD1_1st 200 kevklyerdtweeafklsknklsedisivafSpcGkyla 238 ++v l++ ++ + +l + k++ ++ +v +S + +y+a FUN_001655-T1 473 DSVTLFDVQQ---KRTLATVKVN-KVRYVVWSADMSYVA 507 4444554443...3333333333.345566666666665 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.1 0.0 3.9e-15 2.2e-12 9 165 .. 11 163 .. 3 164 .. 0.51 2 ! 40.7 0.1 3.7e-13 2.1e-10 95 209 .. 50 165 .. 48 202 .. 0.90 3 ! 40.1 0.0 5.3e-13 3e-10 9 120 .. 209 318 .. 205 333 .. 0.93 Alignments for each domain: == domain 1 score: 47.1 bits; conditional E-value: 3.9e-15 WDR55 9 lvvdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllv 104 v i+fhP++ + ++ +G ++l+ y + l +++ h+ +r ++F ++ ++s D +i++ + +++k++ ++ + ++ + FUN_001655-T1 11 RVKGIAFHPTRPWVLASLHNGVIQLWDYRM----CTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFH 102 344555666666666666666666666554....23455555566666666666555555555556666666555555555555333333333333 PP WDR55 105 idenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfn 165 + ++++ dd t+++W ++++++ l+ h+ y+ + ++ ++ l++++s d t+ v++ FUN_001655-T1 103 HEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWD 163 3333555555555666666555555555566666666666666666666665555555555 PP == domain 2 score: 40.7 bits; conditional E-value: 3.7e-13 WDR55 95 hespiysllv.idenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfnirkkklevqseeyeeellslalvk 189 h+ p+ + ++ l+++G dd +k+W + +kk++++l h dyi +++e +++++s d t+ ++n +++++++ +++ +++ ++ FUN_001655-T1 50 HDGPVRGINFhTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHP 145 7777777765156779******************************************************************************** PP WDR55 190 eekkvvvGsseGklylfnwg 209 +e+ vv +s + ++ +++ FUN_001655-T1 146 SEDLVVSASLDQTVRVWDIS 165 ***************99875 PP == domain 3 score: 40.1 bits; conditional E-value: 5.3e-13 WDR55 9 lvvdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllv 104 v+ ++fhP+ +i+ g d +v+l++ + ++ e+ +++ h +++ +v F + ++s s+Dksi+v d+++++ ++++++ h+ + ++ FUN_001655-T1 209 GVNWVAFHPTMPLIVSGADDRQVKLWRMNDSK--AWEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRREHDRFWVAAAH 302 67889***********************9754..5799********************************************************** PP WDR55 105 idenllatGdddGtvk 120 nl+a+G d+G++ FUN_001655-T1 303 PTLNLFAAGHDSGMIV 318 *************985 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.3 0.2 2.2e-19 1.2e-16 130 292 .] 4 162 .. 1 162 [. 0.90 2 ! 29.0 0.2 1.6e-09 8.6e-07 126 218 .. 198 289 .. 192 293 .. 0.87 3 ? 2.8 0.1 0.15 83 29 111 .. 473 548 .. 421 566 .. 0.58 Alignments for each domain: == domain 1 score: 61.3 bits; conditional E-value: 2.2e-19 WD40_CDC20-Fz 130 tlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksvdtgsq.v 224 +++ ++ +v g+++ p++ + + +++++++wd r+++ l +++eh+ v+ ++++ +++ l ++GG +D +i++wn +++k+l ++ + + FUN_001655-T1 4 KFETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQP-LFVSGG--DDYKIKIWNYKQKKCLFTLLGHLDyI 96 6888999**********9888888888*****************************99775.788888..6***************9988876527 PP WD40_CDC20-Fz 225 tsllwskeekelvsthgysknqivlwkypslkkvaeleghtervlslalspdgetvvtasaDetlrfW 292 + ++ +e+ ++s+ +++i++w+++s + + l+gh++ v+ ++ p+++ vv+as D+t+r+W FUN_001655-T1 97 RTTFFHHEYPWIISASD--DQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162 77788888889999875..678********************************************** PP == domain 2 score: 29.0 bits; conditional E-value: 1.6e-09 WD40_CDC20-Fz 126 evvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrsls..pllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkllksv 218 v++ l++h + v +++ p+ l+ sG+ d++vk+w +++++ ++ +++ h v ++ ++p ++ +L ++Dk+ir+w++++ + ++++ FUN_001655-T1 198 IVKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHPRQELILS---NSEDKSIRVWDMSKRTGVQTF 289 5567899********************************9887446899***************9988884...579*********999888775 PP == domain 3 score: 2.8 bits; conditional E-value: 0.15 WD40_CDC20-Fz 29 ssvylwnaetgevkelldlseesdyvtsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalawnenllssGsr 111 +sv l++ +++++ ++ ++v v ws d +++a+ + v +++ k ++l t+++ + rv + aw+en +++ + FUN_001655-T1 473 DSVTLFDVQQKRTLATVK----VNKVRYVVWSADMSYVALL-GKHVVAICNR-KLECLCTIHE-NIRVKSGAWEENGVFVYTT 548 344444444443322222....2356666666666665542.2234444443.4455555543.3466666666665555444 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.015 8.2 235 278 .. 4 47 .. 1 49 [. 0.90 2 ! 58.2 0.1 2e-18 1.1e-15 155 270 .. 49 165 .. 47 169 .. 0.94 3 ! 24.1 0.0 4.7e-08 2.6e-05 154 238 .. 204 291 .. 182 295 .. 0.69 4 ! 18.5 0.0 2.5e-06 0.0014 236 307 .. 247 319 .. 242 329 .. 0.83 5 ? -2.9 0.0 8 4.4e+03 208 280 .. 415 491 .. 405 507 .. 0.49 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.015 Beta-prop_WDR36-Utp21_2nd 235 kfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvf 278 kf+ ++r++ ++f p W++++ i+ wd +l++ f FUN_001655-T1 4 KFETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERF 47 78999999**************************9999998877 PP == domain 2 score: 58.2 bits; conditional E-value: 2e-18 Beta-prop_WDR36-Utp21_2nd 155 ahkkavrGvavdalnqvvitagadkklkfwkfkskklletl.kleasisklvlhressllavalddfsilvvDidtrrvvRkfs 237 h++ vrG+ + + + +++g d k+k+w++k+kk l tl i ++ +h+e + a dd +i++ ++r++ ++ FUN_001655-T1 49 EHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLlGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLT 132 69********************************998876615667899999******************************** PP Beta-prop_WDR36-Utp21_2nd 238 ghknritDltfspdarWlitasmDstirtwdlp 270 gh+ ++ + f p +++as+D t+r+wd++ FUN_001655-T1 133 GHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165 *******************************97 PP == domain 3 score: 24.1 bits; conditional E-value: 4.7e-08 Beta-prop_WDR36-Utp21_2nd 154 kahkkavrGvavdalnqvvitagadkklkfwkfkskklletlk...leasisklvlhressllavalddfsilvvDidtrrvvR 234 + h+ v+ va ++ ++++++ d+++k+w++++ k e + +++s +++h +l+ +d si+v D+ r+ v FUN_001655-T1 204 EGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKAWEVDTcrgHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQ 287 357888888888888888888888888888888887776554411244677888888888888888888888888888888888 PP Beta-prop_WDR36-Utp21_2nd 235 kfsg 238 +f+ FUN_001655-T1 288 TFRR 291 7764 PP == domain 4 score: 18.5 bits; conditional E-value: 2.5e-06 Beta-prop_WDR36-Utp21_2nd 236 fsghknritDltfspdarWlitasmDstirtwdlpsgkliDvflvesaatsls.lsptgdfLatahvddlgvy 307 +gh n+++ ++f p +++ s D +ir+wd+++ + + +f+ e+ ++ pt +++a+ h + v+ FUN_001655-T1 247 CRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRREHDRFWVAaAHPTLNLFAAGHDSGMIVF 319 689****************************************988766555415688888888876666555 PP == domain 5 score: -2.9 bits; conditional E-value: 8 Beta-prop_WDR36-Utp21_2nd 208 ressllavalddfsilvvDidtrrvvRkfsgh.knri....tDltfspdarWlitasmDstirtwdlpsgkliDvflv 280 r s+l av + v+D + +++++++ + ++ +D++f + + l+ +Ds + +d+++ + + + +v FUN_001655-T1 415 RASGLTAVWVARNRFAVLDRTHTLLIKNLKNEvTKKVqtppCDMIFYAGTGSLLLRDTDS-VTLFDVQQKRTLATVKV 491 566666666666666666666666666665431222211113555555554444444443.44455544444433333 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 0.0 2e-09 1.1e-06 40 111 .. 11 82 .. 2 87 .. 0.92 2 ! 27.7 0.7 3.7e-09 2.1e-06 212 287 .. 88 163 .. 83 167 .. 0.76 3 ! 34.7 0.2 2.7e-11 1.5e-08 212 290 .. 202 282 .. 190 325 .. 0.64 4 ? -2.2 0.1 4.7 2.6e+03 2 36 .. 494 527 .. 466 541 .. 0.64 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 2e-09 Beta-prop_WDR3_2nd 40 yalclafvpgdrhvlvgtkdGklevldlasaelletieahegavwsvaltpdekglvtggaDkkvkfwefel 111 ++ +af p vl+++++G +++ d + ++lle+++ h+g v+ ++ ++++ +v+gg D k+k+w+++ FUN_001655-T1 11 RVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQ 82 5667889999999********************************************************986 PP == domain 2 score: 27.7 bits; conditional E-value: 3.7e-09 Beta-prop_WDR3_2nd 212 slfahddsvmsvafvpktHylfsagkdkkvkyWDadkfekiqtleghagevwalavsskgkfvvsashDksiRlwe 287 +l++h d + + f ++ ++sa+ d++++ W+ ++ ++ + l+gh+ v++ + ++vvsas D+++R+w+ FUN_001655-T1 88 TLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWD 163 4667777787777888888888888888888888888888888888888888888888888888888888888886 PP == domain 3 score: 34.7 bits; conditional E-value: 2.7e-11 Beta-prop_WDR3_2nd 212 slfahddsvmsvafvpktHylfsagkdkkvkyW...DadkfekiqtleghagevwalavsskgkfvvsashDksiRlwerte 290 l +hd v vaf p + s + d++vk W D+ k ++ t +gh ++v ++ + ++++s s+DksiR+w++++ FUN_001655-T1 202 VLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWrmnDS-KAWEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSK 282 45667777777777777777777777777777733222.2234666777777777777777777777777777777776543 PP == domain 4 score: -2.2 bits; conditional E-value: 4.7 Beta-prop_WDR3_2nd 2 vRavalssddklllsassesvkiwnvkslecirti 36 vR v s+d ++++ +++ v i n+k lec+ ti FUN_001655-T1 494 VRYVVWSADMSYVALLGKHVVAICNRK-LECLCTI 527 566666666666666666666666543.4565555 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.8 1.4e-06 0.00079 7 71 .. 102 167 .. 98 176 .. 0.85 2 ! 28.6 0.1 2.1e-09 1.2e-06 4 104 .. 213 316 .. 210 317 .. 0.84 3 ! 21.3 0.0 3.7e-07 0.00021 4 65 .. 257 319 .. 254 388 .. 0.85 4 ? 1.7 0.1 0.34 1.9e+02 20 56 .. 473 508 .. 417 554 .. 0.72 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 1.4e-06 Beta-prop_EML_2 7 hpsepqfvTagdDktvrlWdlekkklvakv.klekearsvafspdgkllavGlkdGsvlvldaetl 71 h + p +++a+dD+t+r+W+ +++++ + ++ + +++f+p+++l++ ++ d +v v+d + l FUN_001655-T1 102 HHEYPWIISASDDQTIRIWNWQSRTCTCVLtGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGL 167 7788899****************99999872566789************99999999999876655 PP == domain 2 score: 28.6 bits; conditional E-value: 2.1e-09 Beta-prop_EML_2 4 LathpsepqfvTagdDktvrlWdlekkklvakvkle...kearsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgk 94 +a hp+ p +v++ dD++v lW++++ k +++ +++++v f+p+++l+ ++d s+ v+d ++ + v +++ ++++ + + +p + FUN_001655-T1 213 VAFHPTMPLIVSGADDRQVKLWRMNDSKAWEVDTCRghyNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRREHDRFWVAAAHPTLN 306 699********************99877655444431115799*********************************999999999999999999 PP Beta-prop_EML_2 95 lLavgshdnk 104 l a+g ++ FUN_001655-T1 307 LFAAGHDSGM 316 9999876665 PP == domain 3 score: 21.3 bits; conditional E-value: 3.7e-07 Beta-prop_EML_2 4 LathpsepqfvTagdDktvrlWdlekkklvakvkle.kearsvafspdgkllavGlkdGsvlv 65 + hp+++ +++ ++Dk++r+Wd++k++ v++ + e ++ +a +p +l+a+G ++G ++ FUN_001655-T1 257 VMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRREhDRFWVAAAHPTLNLFAAGHDSGMIVF 319 678***********************9999988666267899999***********9998764 PP == domain 4 score: 1.7 bits; conditional E-value: 0.34 Beta-prop_EML_2 20 ktvrlWdlekkklvakvklekearsvafspdgkllav 56 +v+l+d+++k+++a+vk++ ++r v +s d +++a+ FUN_001655-T1 473 DSVTLFDVQQKRTLATVKVN-KVRYVVWSADMSYVAL 508 45667777777777777766.5666666666666654 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 0.0 5.3e-10 3e-07 185 264 .. 2 79 .. 1 81 [. 0.91 2 ! 19.4 0.1 1.4e-06 0.00077 198 263 .. 98 162 .. 79 164 .. 0.88 3 ! 7.4 0.0 0.0065 3.6 228 264 .. 199 235 .. 194 238 .. 0.87 4 ! 14.2 0.0 5.5e-05 0.031 206 263 .. 220 278 .. 215 281 .. 0.88 5 ! 7.0 0.0 0.0086 4.8 124 175 .. 267 318 .. 264 324 .. 0.89 6 ? 1.4 0.0 0.45 2.5e+02 181 223 .. 352 397 .. 348 410 .. 0.79 7 ? -0.0 0.0 1.2 6.6e+02 148 200 .. 442 499 .. 430 562 .. 0.69 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 5.3e-10 Beta-prop_WDR36-Utp21_1st 185 llklkqeegpvtsisFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkewi 264 l k+++++++v i+F + vla + ++G i lwd +l++ + H+g+v +++f ++qpl+v+ g D ++k+w FUN_001655-T1 2 LTKFETKSARVKGIAFHPTRPWVLA-SLHNGVIQLWDYRMCTLLERF-DEHDGPVRGINFHTNQPLFVSGGDDYKIKIWN 79 6799999*********998777666.5789***************99.68*****************************6 PP == domain 2 score: 19.4 bits; conditional E-value: 1.4e-06 Beta-prop_WDR36-Utp21_1st 198 isFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaDNslkew 263 +F + + p ++++s++ +i +w+ ++r+ ++vl + H++ v +++f p++ l+v+++ D ++++w FUN_001655-T1 98 TTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVL-TGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162 5678888999******************999999.67****************************9 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0065 Beta-prop_WDR36-Utp21_1st 228 vhvlrnaHeggvtkleflpgqpllvtsgaDNslkewi 264 v+ + + H+ gv+ + f p+ pl+v+ + D ++k w FUN_001655-T1 199 VKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWR 235 5555678*****************************6 PP == domain 4 score: 14.2 bits; conditional E-value: 5.5e-05 Beta-prop_WDR36-Utp21_1st 206 pvlatgsssGdialwdLekrrlvhv.lrnaHeggvtkleflpgqpllvtsgaDNslkew 263 p++++g ++ ++ lw +++++ +v + + H ++v+++ f p+q+l++++++D s+++w FUN_001655-T1 220 PLIVSGADDRQVKLWRMNDSKAWEVdTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVW 278 7889999999********997766525567999************************** PP == domain 5 score: 7.0 bits; conditional E-value: 0.0086 Beta-prop_WDR36-Utp21_1st 124 lvgskqGslqlwNirtgkliytfksfksaitaleqspaldvvaiglasGeiv 175 l s++ s+++w++++++ + tf++ +++ + + p l++ a g+ sG iv FUN_001655-T1 267 LSNSEDKSIRVWDMSKRTGVQTFRREHDRFWVAAAHPTLNLFAAGHDSGMIV 318 55677889999*************999********************99997 PP == domain 6 score: 1.4 bits; conditional E-value: 0.45 Beta-prop_WDR36-Utp21_1st 181 kdetllklkqe..egpvtsisFrtDgepvlatgs.ssGdialwdLe 223 kd +++++ + ++pv s+sF ++ vl++++ s+ + ++++L FUN_001655-T1 352 KDVPVMQFRRNssRTPVYSMSFNPAENCVLLCTNaSNPENCVYELH 397 7999****9874466********99987666555277888888775 PP == domain 7 score: -0.0 bits; conditional E-value: 1.2 Beta-prop_WDR36-Utp21_1st 148 sfksaitaleqspaldvvaig.......lasGeivlhnikkdetllklkqeegpvtsisF 200 ++k+++t +q+p +d++ + +++++l+++++ +tl ++k + +v+ + FUN_001655-T1 442 NLKNEVTKKVQTPPCDMIFYAgtgslllRDTDSVTLFDVQQKRTLATVKVN--KVRYVVW 499 556666666666666665322111111124677888888888888888776..4444444 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 0.0 1e-09 5.7e-07 160 255 .. 27 122 .. 21 127 .. 0.92 2 ! 20.3 0.2 5.5e-07 0.00031 157 214 .. 108 165 .. 98 180 .. 0.89 3 ! 13.0 0.1 9.5e-05 0.053 138 189 .. 130 182 .. 124 201 .. 0.75 4 ! 28.6 0.0 1.7e-09 9.5e-07 177 264 .. 200 289 .. 185 313 .. 0.88 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 1e-09 WD40_Gbeta 160 ssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsddatcrlfdl 255 s + lwd f h g v +++ ++ lfvsg d +k+w+ ++ c t++gh i + f + + + sdd t r+++ FUN_001655-T1 27 SLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNW 122 55566789***********************************************************9999998888888999*********9875 PP == domain 2 score: 20.3 bits; conditional E-value: 5.5e-07 WD40_Gbeta 157 ivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvr 214 i+++s d t +w+ ++ t+v++gh+ vm + p l+vs + d ++++wd+ FUN_001655-T1 108 IISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165 89999***************************************************85 PP == domain 3 score: 13.0 bits; conditional E-value: 9.5e-05 WD40_Gbeta 138 elaghtgylsccrflddnqiv.tssgdttcalwdietgqqttvfvghtgdvms 189 l+gh y+ c++f +++v ++s d t+ +wdi +++tv g +g FUN_001655-T1 130 VLTGHNHYVMCAQFHPSEDLVvSASLDQTVRVWDISGLRKKTVAPGTSGLDEH 182 5899999******998777651557899*******999999999998885444 PP == domain 4 score: 28.6 bits; conditional E-value: 1.7e-09 WD40_Gbeta 177 ttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcr..qtfighesdinaiaffpngealatgsddatcrlfdlradqellvy 264 + v+ gh v +++ p + l+vsga d +klw + ++ + +t gh ++ ++ f p e + + s+d + r++d+ + ++ FUN_001655-T1 200 KHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKAWevDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTF 289 5678899999*****************************9885226899*******************************9776666655 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.0 0.1 5.9e-23 3.3e-20 15 169 .. 613 769 .. 597 780 .. 0.92 Alignments for each domain: == domain 1 score: 73.0 bits; conditional E-value: 5.9e-23 TPR_COPA_B 15 evLpsipkeqr..nrvarFLekqgfkeeaLevstdpehkFdLalqlgklevalelakeadseqkwkqlgdlalkkgklklaeeclekakdlsglLL 108 evL+ + + + +++ +L+k+g+ e aL+ +d++ +F Lal+ g++evale a+ d+++ w +lg +al++g+ +++e +++++k+++ l + FUN_001655-T1 613 EVLHMVRNAKLvgQSIISYLQKKGYPEVALHFVKDEKTRFGLALECGNIEVALEAARGLDDKACWERLGAAALTQGNHQVVEMAYQRTKNFDKLSF 708 556666554432278999****************************************************************************** PP TPR_COPA_B 109 latssgnaegleklaekaeekgknniaFlalfllgklekclelLiktdrlpEAalfartYl 169 l+ +gn e+l k+++ ae ++ + ++ + +g++e+ +++L + ++ + A l a t+ FUN_001655-T1 709 LYLITGNLEKLGKMTKIAEIRKDTSGQYHNALYTGDVEERIKILKNLGQGSLAYLTAATHG 769 *********************************************************9984 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0045 2.5 156 206 .. 35 85 .. 15 89 .. 0.60 2 ! 32.4 0.2 1.2e-10 6.5e-08 66 204 .. 47 167 .. 37 174 .. 0.88 3 ! 36.9 0.6 5e-12 2.8e-09 65 360 .. 202 502 .. 175 509 .. 0.78 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0045 Beta-prop_CAF1B_HIR1 156 lWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkv 206 lWd + ++ l+ +++h g v+g+ + ++ ++++ D +++i++ k+kk+ FUN_001655-T1 35 LWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKC 85 566666666666666666666666666555556666666666666665555 PP == domain 2 score: 32.4 bits; conditional E-value: 1.2e-10 Beta-prop_CAF1B_HIR1 66 ltrhqkavnvvrfspsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlswspdskklisgsvDnta 154 ++ h +v + f +++ l sg+D+ +i iW+ k+++ +l +l Ghl+ + + ++ +is+s D t+ FUN_001655-T1 47 FDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKK------------------CLFTLLGHLDYIRTTFFHHEYPWIISASDDQTI 117 56788888888899999999999999999999888875..................233789*************************** PP Beta-prop_CAF1B_HIR1 155 ilWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktk 204 +W+ + + + +l+ h+++v + P++++v+++s D+++r++di+ FUN_001655-T1 118 RIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGL 167 **********************************************9864 PP == domain 3 score: 36.9 bits; conditional E-value: 5e-12 Beta-prop_CAF1B_HIR1 65 dltrhqkavnvvrfspsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlswspdskklisgsvDnt 153 l+ h + vn v f p+ l+ sg D+ ++ +W++++++ w + + rGh ++v + + p ++ ++s s D + FUN_001655-T1 202 VLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSK---------------AWE-VDTCRGHYNNVSCVMFHPRQELILSNSEDKS 274 5889******************************99885...............343.4688*************************** PP Beta-prop_CAF1B_HIR1 154 ailWdvekgkklailk.dhkgfvqgvawdPknqyvatlssDrslrifdiktkkvvarvskaklpvkeekelkekevrlfhddtlksffr 241 + +Wd++k + ++ ++ +h f + a +n + + D + +f+++ ++ ++ v+ ++l ++e+ l+ e+ d + f r FUN_001655-T1 275 IRVWDMSKRTGVQTFRrEHDRFWVAAAHPTLNLFA--AGHDSGMIVFKLERERPAYAVHGNTLYYAKERYLRMYEFGTSKDVPVMQFRR 361 ********999888752777777666655555444..46799999******************99999999999999999999999999 PP Beta-prop_CAF1B_HIR1 242 rltfspdGkllivPaGiie..eeeskkvlnaty....ifsrkslkkPvlvlpslekatvavrccpvlfelree............keep 312 + +p ++ + Pa + ++++++ n++y + + ++P + +av ++ f + ++ +++ FUN_001655-T1 362 NSSRTPVYSMSFNPAENCVllCTNASNPENCVYelhaVPKEIDSSNPEVSEGKRASGLTAVWVARNRFAVLDRthtlliknlkneVTKK 450 99999999999999864431133345566665521113334456777777777777778888888888877767788888888767788 PP Beta-prop_CAF1B_HIR1 313 liklPyrlvfavat.......kksvllYDtqqkvPfalisnihytrltDlaWssd 360 + + P ++f +t ++sv+l+D qqk +a+++ +++ + Ws d FUN_001655-T1 451 VQTPPCDMIFYAGTgslllrdTDSVTLFDVQQKRTLATVK---VNKVRYVVWSAD 502 889999***9988844444445799999*9*999999875...466666777776 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 1.3e-06 0.00073 33 112 .. 6 85 .. 2 98 .. 0.88 2 ! 16.2 1.0 1.2e-05 0.0066 10 66 .. 109 165 .. 101 171 .. 0.93 3 ! 11.5 0.0 0.00032 0.18 213 283 .. 198 269 .. 190 271 .. 0.80 4 ! 20.6 0.0 5.5e-07 0.0003 13 65 .. 270 321 .. 267 328 .. 0.92 5 ? -2.7 0.0 6.9 3.9e+03 209 247 .. 481 516 .. 429 551 .. 0.60 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 1.3e-06 Beta-prop_WDR90_POC16_2nd 33 saseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgeylysacslGslalydaseeey 112 ++++ +afhP+++ + + ++Gv++ ++ + +ll + +h g v g+ f + ++ s + ++ +++ +++++ FUN_001655-T1 6 ETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKC 85 5555566779************************************************9999999999999999888776 PP == domain 2 score: 16.2 bits; conditional E-value: 1.2e-05 Beta-prop_WDR90_POC16_2nd 10 atvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsve 66 +s+D+tiriW+ ++ + ++ ++ ++ fhPs++++++ + + +vrv++++ FUN_001655-T1 109 ISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165 6789*************************************************9986 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00032 Beta-prop_WDR90_POC16_2nd 213 llrevsevhrsacsslavsedaryllt.agdkvikvwdysmkldinfqvfiGhsekvqqvaftpdqqevlsv 283 ++++v e h +++ +a +++ a d+ +k+w + ++ ++ Gh ++v+ v+f p q+ +ls FUN_001655-T1 198 IVKHVLEGHDRGVNWVAFHPTMPLIVSgADDRQVKLWRMNDSKAWEVDTCRGHYNNVSCVMFHPRQELILSN 269 666777777777777777777777776245799*******************************99999985 PP == domain 4 score: 20.6 bits; conditional E-value: 5.5e-07 Beta-prop_WDR90_POC16_2nd 13 seDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsv 65 seD++ir+Wd++ + + f +++ + a hP+ ++fa+G +sG++ vf++ FUN_001655-T1 270 SEDKSIRVWDMSKRTGVQTFRREHDRFWVAAAHPTLNLFAAGHDSGMI-VFKL 321 89********************************************98.5666 PP == domain 5 score: -2.7 bits; conditional E-value: 6.9 Beta-prop_WDR90_POC16_2nd 209 ktGrllrevsevhrsacsslavsedarylltagdkvikv 247 ++ r+l+ +v+ +++ + s d +y++ g++v+ + FUN_001655-T1 481 QQKRTLA---TVKVNKVRYVVWSADMSYVALLGKHVVAI 516 3322222...22333333444455555555555555555 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 1.6e-05 0.0087 141 223 .. 4 86 .. 1 90 [. 0.90 2 ! 19.9 0.2 8.5e-07 0.00047 6 82 .. 89 165 .. 84 176 .. 0.88 3 ! 27.6 0.1 3.6e-09 2e-06 5 91 .. 202 290 .. 200 302 .. 0.91 4 ? 0.8 0.0 0.53 2.9e+02 90 162 .. 362 431 .. 338 454 .. 0.71 5 ? -1.7 0.1 3.2 1.8e+03 75 114 .. 474 512 .. 464 558 .. 0.71 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.6e-05 EIF3I 141 kieveeskvtvalwsaldktiitghedgeiskydlktgeklksvkehekqitdlqlskdktylitaskDktaklldvetlevl 223 k+e+++++v+ +++ + ++++ ++g i+ +d ++ + l++ +eh+ ++ +++++++ ++++ D + k+++ ++ ++l FUN_001655-T1 4 KFETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCL 86 56778888999999999999*************************************************99999999887765 PP == domain 2 score: 19.9 bits; conditional E-value: 8.5e-07 EIF3I 6 lkGheRaltqikynreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdve 82 l Gh + + +e ++s++ d+++ +w + ++Gh+ v++ + + + +l+v++s d+tv++Wd++ FUN_001655-T1 89 LLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165 6677777777788888889999**********999999999999******************************986 PP == domain 3 score: 27.6 bits; conditional E-value: 3.6e-09 EIF3I 5 llkGheRaltqikynreGDllfsvakdkkasvwysenGe..rlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktle 91 +l+Gh+R ++ + + l++s a d+++ +w +++ + t +Gh v ++ + + +l+++ s d+++++Wd+++ + ++t++ FUN_001655-T1 202 VLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFR 290 699******************************98876633699***********************************9877777765 PP == domain 4 score: 0.8 bits; conditional E-value: 0.53 EIF3I 90 letktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlkieveeskvtvalwsaldktii 162 + +t+v s++f++ ++ +ll+t+ +++ ++ + +e +++++p ++ ++++ +a+w a +++ + FUN_001655-T1 362 NSSRTPVYSMSFNPAENCVLLCTNASNPENCVYELHAVPKE--IDSSNPEVSEG-KRASGLTAVWVARNRFAV 431 456899******************99999988888777554..44444444433.333444566766666655 PP == domain 5 score: -1.7 bits; conditional E-value: 3.2 EIF3I 75 tvklWdvetGkelktletktavrsvefsesgkllllvtdk 114 +v l+dv++ ++l+t++++ +vr v +s + ++++l ++ FUN_001655-T1 474 SVTLFDVQQKRTLATVKVN-KVRYVVWSADMSYVALLGKH 512 6778888888888888875.57888888777766655444 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.8 0.4 5.6e-12 3.1e-09 85 211 .. 46 171 .. 32 183 .. 0.83 2 ! 28.0 0.3 2.9e-09 1.6e-06 82 177 .. 199 293 .. 187 323 .. 0.82 Alignments for each domain: == domain 1 score: 36.8 bits; conditional E-value: 5.6e-12 Beta-prop_TEP1_2nd 85 vlrghtgavtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkd.dllvscssdGsvglWdiekeqrlgkfl 174 + +h+g+v f ++ l+ +gg d ++ +W+ ++ k l + l h d++ + + ++ ++s+s+d ++++W+ ++++ ++ FUN_001655-T1 46 RFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKC--L-FT-LLGHLDYIRTTFFHHEyPWIISASDDQTIRIWNWQSRTCTCVLT 132 5679******************************999443..3.33.457*****888776652689************************ PP Beta-prop_TEP1_2nd 175 Ghqsavsav..vaveehvvsvgrdGllkvWdlqGvelts 211 Gh+ v ++ e+ vvs + d +++vWd +G+ + FUN_001655-T1 133 GHNHYVMCAqfHPSEDLVVSASLDQTVRVWDISGLRKKT 171 **998865511467999****************997655 PP == domain 2 score: 28.0 bits; conditional E-value: 2.9e-09 Beta-prop_TEP1_2nd 82 slsvlrghtgavtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWt.kddllvscssdGsvglWdiekeqrlg 171 ++vl gh+ +v+ +f + l+ +g+ dr++ +W ++++ka + h + v++ + +++l++s s+d s+++Wd++k++ ++ FUN_001655-T1 199 VKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKAWEV--DTCRGHYNNVSCVMFHpRQELILSNSEDKSIRVWDMSKRTGVQ 287 5679********************************9999877655..445679999999987537899********************** PP Beta-prop_TEP1_2nd 172 kflGhq 177 +f + FUN_001655-T1 288 TFRREH 293 *97544 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 2.8e-05 0.016 155 232 .. 8 85 .. 2 105 .. 0.83 2 ! 19.7 0.4 1.2e-06 0.00066 82 140 .. 108 166 .. 100 185 .. 0.83 3 ! 25.5 0.1 2e-08 1.1e-05 7 122 .. 205 306 .. 200 356 .. 0.80 4 ? -1.6 0.1 3.9 2.2e+03 90 113 .. 474 497 .. 466 553 .. 0.61 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.8e-05 Beta-prop_EML 155 kpkyvlclafsengd.vitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivawdanlekl 232 k v +af+++ v++ nG i +W+ ++ + h+g+v + + +++ l ++gg d ki+ w+ + +k+ FUN_001655-T1 8 KSARVKGIAFHPTRPwVLASLHNGVIQLWDYRMCTLLERFD-EHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKC 85 5667788888888765889999********99988888866.8*****************************9776665 PP == domain 2 score: 19.7 bits; conditional E-value: 1.2e-06 Beta-prop_EML 82 avdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhiaFWtleg 140 ++ s+++++ +W+wq+++ + +++++ v++++fhp+++ ++ + + W ++g FUN_001655-T1 108 IISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISG 166 678899********************************987665555677778887764 PP == domain 3 score: 25.5 bits; conditional E-value: 2e-08 Beta-prop_EML 7 gHtddikclavhpnkllvatGqvagsskdekeakphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgekl 102 gH+ ++ +a hp+ l+++G +++ W+++ + +v + + ++vsc+ F +++ +++ +s+++++ vWd++k++ + FUN_001655-T1 205 GHDRGVNWVAFHPTMPLIVSGADD----------RQVKLWRMNDSKAWEVDTCRGHYNNVSCVMFHPRQE----LILSNSEDKSIRVWDMSKRTGV 286 89999***************9853..........469***************999***********8764....567899999************* PP Beta-prop_EML 103 aetktskdkvlavefhpldk 122 ++ + ++d+ +++ hp+ + FUN_001655-T1 287 QTFRREHDRFWVAAAHPTLN 306 *****************853 PP == domain 4 score: -1.6 bits; conditional E-value: 3.9 Beta-prop_EML 90 vlsvWdwqkgeklaetktskdkvl 113 +++++d+q+++ la++k++k + + FUN_001655-T1 474 SVTLFDVQQKRTLATVKVNKVRYV 497 455666666666666665554333 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.0 0.022 12 11 34 .. 62 85 .. 50 91 .. 0.82 2 ! 11.9 0.1 0.00045 0.25 13 31 .. 106 124 .. 92 132 .. 0.83 3 ! 14.0 0.0 9.8e-05 0.055 7 31 .. 142 166 .. 134 173 .. 0.81 4 ! 15.5 0.0 3.3e-05 0.018 11 43 .. 218 250 .. 211 264 .. 0.80 5 ! 10.7 0.0 0.0011 0.59 10 39 .. 261 290 .. 250 319 .. 0.80 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.022 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdretkkq 34 + l +s D ++K+W+ ++kk FUN_001655-T1 62 NQPLFVSGGDDYKIKIWNYKQKKC 85 5567899************99996 PP == domain 2 score: 11.9 bits; conditional E-value: 0.00045 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdret 31 +iisAs D+t+++W+ ++ FUN_001655-T1 106 PWIISASDDQTIRIWNWQS 124 58*************9876 PP == domain 3 score: 14.0 bits; conditional E-value: 9.8e-05 Beta-prop_TEP1_C 7 alkltddliisAseDrtvKlWdret 31 + + +dl++sAs D+tv++Wd + FUN_001655-T1 142 QFHPSEDLVVSASLDQTVRVWDISG 166 566789****************765 PP == domain 4 score: 15.5 bits; conditional E-value: 3.3e-05 Beta-prop_TEP1_C 11 tddliisAseDrtvKlWdretkkqvGlFvCeap 43 t li+s + Dr+vKlW+ ++ k + +C++ FUN_001655-T1 218 TMPLIVSGADDRQVKLWRMNDSKAWEVDTCRGH 250 6678*******************9999999885 PP == domain 5 score: 10.7 bits; conditional E-value: 0.0011 Beta-prop_TEP1_C 10 ltddliisAseDrtvKlWdretkkqvGlFv 39 ++li+s seD+++++Wd ++ v F+ FUN_001655-T1 261 PRQELILSNSEDKSIRVWDMSKRTGVQTFR 290 45789***************9888887776 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.19 1e+02 31 71 .. 5 44 .. 1 50 [. 0.79 2 ! 7.4 0.1 0.0059 3.2 12 66 .. 68 123 .. 57 128 .. 0.82 3 ! 21.7 0.3 2.6e-07 0.00015 8 71 .. 107 169 .. 101 177 .. 0.84 4 ! 20.1 0.1 8e-07 0.00044 183 259 .. 207 282 .. 197 291 .. 0.85 5 ? 1.7 0.0 0.34 1.9e+02 184 208 .. 294 318 .. 290 330 .. 0.86 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.19 Beta-prop_WDR75_1st 31 lkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgili 71 +++++ v G+a++p+ v ++ +g ++lwd+ l+ FUN_001655-T1 5 FETKSARVKGIAFHPTRPW-VLASLHNGVIQLWDYRMCTLL 44 567778999******9775.6677889********876665 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0059 Beta-prop_WDR75_1st 12 asGd..svkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdft 66 + Gd +k++ + ++c+ +l gh d + ++ + + s+s d t+r+w++ FUN_001655-T1 68 SGGDdyKIKIWNYKQKKCLFTLLGHLDYIRTTFFHH-EYPWIISASDDQTIRIWNWQ 123 4454336899*******************9888765.566799***********985 PP == domain 3 score: 21.7 bits; conditional E-value: 2.6e-07 Beta-prop_WDR75_1st 8 fllcasGd.svkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgili 71 +++ as d +++++ ++ c +l gh++ v +++ps++l v s+sld tvr+wd g+ FUN_001655-T1 107 WIISASDDqTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDL-VVSASLDQTVRVWDI-SGLRK 169 56777765369*******************************9.569***********5.45555 PP == domain 4 score: 20.1 bits; conditional E-value: 8e-07 Beta-prop_WDR75_1st 183 knaftcvachpkddciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnllsGGvesvlvqwryee 259 + va hp+ i +G +d +++lwr +n+ k + t h++ vs ++f p +ls + + w +++ FUN_001655-T1 207 DRGVNWVAFHPTMPLIVSGADDRQVKLWR-MNDSKAWEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSK 282 55667899********************9.6889999********************99999998887777777665 PP == domain 5 score: 1.7 bits; conditional E-value: 0.34 Beta-prop_WDR75_1st 184 naftcvachpkddciatGhedGkir 208 + f + a+hp+ + a+Gh+ G i FUN_001655-T1 294 DRFWVAAAHPTLNLFAAGHDSGMIV 318 678899****************985 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 1.7e-07 9.3e-05 153 280 .] 4 120 .. 2 120 .. 0.90 2 ! 21.4 0.6 3.5e-07 0.00019 219 280 .] 107 162 .. 92 162 .. 0.86 3 ! 11.5 0.1 0.00038 0.21 207 280 .] 210 278 .. 193 278 .. 0.78 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 1.7e-07 Beta-prop_EIPR1 153 kyslggeelrvaAldphdsslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstveklk 246 k++++++++++ A+ p + + + + +ql+D R + ++ ++g vr ++f++ ++ +++ gdd ++i+ + ++ l FUN_001655-T1 4 KFETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLE----RFDEHDGPVRGINFHTNQP-LFVSGGDDYKIKIWNYK-----QKKCLF 87 78889999***********9998888899*******999998....788889********98766.8**************99.....666777 PP Beta-prop_EIPR1 247 elkaheHtvkkvlfNpfydeLilscssdstlkLw 280 +l +h ++++ f +y i+s+s d+t+++w FUN_001655-T1 88 TLLGHLDYIRTTFFHHEYP-WIISASDDQTIRIW 120 8999*9******9999986.799*********99 PP == domain 2 score: 21.4 bits; conditional E-value: 3.5e-07 Beta-prop_EIPR1 219 klltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 +++a dd ++ i+ + + +++l +h+H v ++f p +L++s+s d+t++ w FUN_001655-T1 107 WIISASDDQTIRIWNWQ-----SRTCTCVLTGHNHYVMCAQFHPSE-DLVVSASLDQTVRVW 162 5799***********99.....6677899***************85.6************99 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00038 Beta-prop_EIPR1 207 vravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 v+ v f+p+ +++ dd +v+++ R++ s + ++ + ++h v+ v f p ++eLils s d+ ++ w FUN_001655-T1 210 VNWVAFHPTM-PLIVSGADDRQVKLW--RMNDS-KAWEVDTCRGHYNNVSCVMFHP-RQELILSNSEDKSIRVW 278 5566677654.468899999*****9..55554.556788999***********99.689*********99998 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0059 3.3 58 116 .. 27 83 .. 4 89 .. 0.80 2 ! 15.4 0.1 2.1e-05 0.012 62 113 .. 115 164 .. 98 175 .. 0.88 3 ! 18.3 0.1 2.9e-06 0.0016 30 119 .. 199 286 .. 189 292 .. 0.86 4 ? 5.1 0.2 0.029 16 62 150 .. 473 554 .. 461 569 .. 0.78 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0059 WD40_MABP1-WDR62_1st 58 sghlpavrvwdvaeksqvaelqkhkygvacvafspnekyivsvgyqhdmvvnvwdwkkd 116 s h+ ++++wd + + +++h v ++f +n+ vs g +++ +++w++k++ FUN_001655-T1 27 SLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYK--IKIWNYKQK 83 569999*************************************98776..566776643 PP == domain 2 score: 15.4 bits; conditional E-value: 2.1e-05 WD40_MABP1-WDR62_1st 62 pavrvwdvaeksqvaelqkhkygvacvafspnekyivsvgyqhdmvvnvwdw 113 ++r+w+ + ++ l++h++ v c +f p+e +vs d +v vwd FUN_001655-T1 115 QTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSA--SLDQTVRVWDI 164 689*********************************998..78999999985 PP == domain 3 score: 18.3 bits; conditional E-value: 2.9e-06 WD40_MABP1-WDR62_1st 30 qkhilntsrkalsalafspdGkylvtGesghlpavrvwdvaeks..qvaelqkhkygvacvafspnekyivsvgyqhdmvvnvwdwkkd 116 kh+l+ + + +af p ++v+G v++w +++ + +v + ++h v+cv f p ++ i s d+ + vwd k FUN_001655-T1 199 VKHVLEGHDRGVNWVAFHPTMPLIVSGADD--RQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHPRQELILSN--SEDKSIRVWDMSKR 283 589999999*****************9766..679***9987642279999*******************986..7899******9998 PP WD40_MABP1-WDR62_1st 117 vvv 119 + v FUN_001655-T1 284 TGV 286 755 PP == domain 4 score: 5.1 bits; conditional E-value: 0.029 WD40_MABP1-WDR62_1st 62 pavrvwdvaeksqvaelqkhkygvacvafspnekyivsvgyqhdmvvnvwdwkkdvvvaankvsskvtavsfsedssyfvtvGnrhvkf 150 +v ++dv++k+ +a+++ k v v s++++y+ +g++ vv + + k +++ + +v + ++ e+ fv + h+k+ FUN_001655-T1 473 DSVTLFDVQQKRTLATVKVNK--VRYVVWSADMSYVALLGKH---VVAICNRKLECLCTIH-ENIRVKSGAWEEN-GVFVYTTSNHIKY 554 57999************9988..9999********9999864...6777777777766543.4567777777665.5566666678887 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.49 2.7e+02 36 78 .. 7 49 .. 3 52 .. 0.88 2 ? 7.2 0.0 0.015 8.2 35 76 .. 48 89 .. 34 103 .. 0.88 3 ? 0.0 0.1 2.6 1.4e+03 35 67 .. 132 164 .. 107 172 .. 0.73 4 ! 28.3 0.0 4e-09 2.2e-06 2 81 .. 214 294 .. 213 305 .. 0.91 5 ? -1.1 0.0 5.7 3.1e+03 59 88 .. 472 499 .. 459 506 .. 0.78 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.49 ANAPC4_WD40 36 kedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsa 78 ++++v+++a++p + ++g ++l d +l++ ++ FUN_001655-T1 7 TKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDE 49 57789**************************999999988875 PP == domain 2 score: 7.2 bits; conditional E-value: 0.015 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgklvhsl 76 +++d+ v++++++ + l++ + +d ++++ + +++k++ +l FUN_001655-T1 48 DEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTL 89 7899*********************************99875 PP == domain 3 score: 0.0 bits; conditional E-value: 2.6 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldv 67 +++ v + +++p++ l + a d +vr+ d+ FUN_001655-T1 132 TGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164 556777888888888888888888888888776 PP == domain 4 score: 28.3 bits; conditional E-value: 4e-09 ANAPC4_WD40 2 swcpkmDLiAlatedgevllkRlnwqrvwkl.seekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksd 81 ++ p+m Li+ + +d +v l R+n + w++ + ++ ++v+++ ++p +l+ +d ++r+ d+++ + v++++ ++d FUN_001655-T1 214 AFHPTMPLIVSGADDRQVKLWRMNDSKAWEVdTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRREHD 294 689****************************54567889******************************999999987766 PP == domain 5 score: -1.1 bits; conditional E-value: 5.7 ANAPC4_WD40 59 dgevrlldvesgklvhslsaksdkitcleW 88 + +v l+dv++++++ ++++++ + W FUN_001655-T1 472 TDSVTLFDVQQKRTLATVKVNKV--RYVVW 499 55799999999999999988765..55555 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.2 1.2e-07 6.9e-05 108 270 .. 29 180 .. 6 183 .. 0.80 2 ! 11.2 0.0 0.00033 0.18 127 220 .. 204 293 .. 193 302 .. 0.77 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.2e-07 WD40_MABP1-WDR62_2nd 108 rsGniriydletleellkieahdsevlcleyskpetglkllasasRDRlihvfdvekdysllqtlddhsssitavkfaeeeeklklisc 196 +G i+++d ++ + l +++ hd+ v +++++ ++ l++s++ D i++++ +++ ++l tl h i + f + e ++is+ FUN_001655-T1 29 HNGVIQLWDYRMCTLLERFDEHDGPVRGINFHT---NQPLFVSGGDDYKIKIWNYKQK-KCLFTLLGHLDYIRTTFFHH--EYPWIISA 111 689999999999999999999999999999975...5689999999999999998766.67789999999999887766..46789999 PP WD40_MABP1-WDR62_2nd 197 gaDksilfrkaqktkegvefsrehhvvekttlydmevdaskklvavacqDrnirvynvssgkqkksfkgsqsed 270 + D++i + + q+ + ++ ++ ++h v + + ++s++lv+ a+ D+++rv+++s ++k++ g+++ d FUN_001655-T1 112 SDDQTIRIWNWQSRTCTCVLTGHNHYVMCA-----QFHPSEDLVVSASLDQTVRVWDISGLRKKTVAPGTSGLD 180 999999999999887766666666655444.....567899999999999999999999888888888877655 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00033 WD40_MABP1-WDR62_2nd 127 eahdsevlcleyskpetglkllasasRDRlihvfdvekdysl.lqtlddhsssitavkfaeeeeklkliscgaDksilfrkaqktkegv 214 e hd v + + + + l++s++ DR ++++ ++++ + + t h +++v f ++e ++s + Dksi + +++k + FUN_001655-T1 204 EGHDRGVNWVAF---HPTMPLIVSGADDRQVKLWRMNDSKAWeVDTCRGHYNNVSCVMFHPRQE--LILSNSEDKSIRVWDMSKRTGVQ 287 556655544444...4457899999999999999998766542679999999999999988654..46899999999999999888888 PP WD40_MABP1-WDR62_2nd 215 efsreh 220 +f+reh FUN_001655-T1 288 TFRREH 293 898887 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.57 3.2e+02 61 94 .. 50 82 .. 37 88 .. 0.88 2 ! 7.4 0.0 0.006 3.4 46 99 .. 74 129 .. 57 141 .. 0.72 3 ? 5.7 0.0 0.02 11 61 93 .. 134 165 .. 127 172 .. 0.88 4 ! 19.1 0.1 1.6e-06 0.00091 61 130 .. 250 318 .. 206 323 .. 0.92 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.57 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltslls 94 H ++R++ F+++ + l +s + D ++k+ + ++ FUN_001655-T1 50 HDGPVRGINFHTN-QPLFVSGGDDYKIKIWNYKQ 82 8999*******98.89************988665 PP == domain 2 score: 7.4 bits; conditional E-value: 0.006 WD40_RFWD3 46 kissldlkssq..yikl.HskaiRdlaFnseqdslllsaslDktlkltsllsntvvq 99 ki+ + k+++ + l H + iR F++e +++sas D+t+++ + +s t + FUN_001655-T1 74 KIKIWNYKQKKclFTLLgHLDYIRTTFFHHE-YPWIISASDDQTIRIWNWQSRTCTC 129 55555555444115555699********999.899*************999988665 PP == domain 3 score: 5.7 bits; conditional E-value: 0.02 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsll 93 H++ + ++F+++ + l++saslD+t+++ +++ FUN_001655-T1 134 HNHYVMCAQFHPS-EDLVVSASLDQTVRVWDIS 165 778888899***9.88************99875 PP == domain 4 score: 19.1 bits; conditional E-value: 1.6e-06 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsntvvqtYetdspvWsCcWseddsnylyaGlqnGsvl 130 H +++ ++F+++ ++l+ls s Dk++++ ++++ t vqt++ +++ + ++ n++ aG G ++ FUN_001655-T1 250 HYNNVSCVMFHPR-QELILSNSEDKSIRVWDMSKRTGVQTFRREHDRFWVAAAHPTLNLFAAGHDSGMIV 318 88889999****9.89***************************99877777799999*******999986 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.3 5.2e-08 2.9e-05 319 416 .. 66 166 .. 50 173 .. 0.80 2 ! 9.6 0.0 0.0009 0.5 334 416 .. 195 282 .. 185 294 .. 0.71 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 5.2e-08 Beta-prop_SCAP 319 vvtGsqdhtvrvyrledscclftlqGhsGgitavyi.dqtmvlasGGqdGaiclwdvltGsrvshvyghrGdvtslvc..ttscvissGlddlis 410 v+G d+ ++++ + clftl Gh i + + + + s d +i +w+ + + + gh v + + v+s+ ld + FUN_001655-T1 66 FVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFhHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFhpSEDLVVSASLDQTVR 160 599***************************966665155667788888888888887766666667777766665555116679*********** PP Beta-prop_SCAP 411 iwdrst 416 +wd s FUN_001655-T1 161 VWDISG 166 ***885 PP == domain 2 score: 9.6 bits; conditional E-value: 0.0009 Beta-prop_SCAP 334 edscclftlqGhsGgitavyidqtmvl.asGGqdGaiclwdvltGs..rvshvyghrGdvtslvct..tscvissGlddlisiwdrst 416 d+ l+Gh g+ v tm l sG d + lw + v gh +v+ +++ ++s d i +wd s FUN_001655-T1 195 SDAIVKHVLEGHDRGVNWVAFHPTMPLiVSGADDRQVKLWRMNDSKawEVDTCRGHYNNVSCVMFHprQELILSNSEDKSIRVWDMSK 282 5777778899999999999999999652688888999999865432125777777777777777642256788888899999999874 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.5 1.9e-07 0.00011 35 158 .. 44 163 .. 38 163 .. 0.79 2 ! 12.7 0.3 0.0001 0.055 57 121 .. 109 166 .. 101 180 .. 0.83 3 ? 1.5 0.0 0.24 1.3e+02 313 358 .. 198 244 .. 192 248 .. 0.80 4 ? 5.6 0.1 0.014 7.7 320 354 .. 249 284 .. 244 292 .. 0.78 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.9e-07 Beta-prop_WDR41 35 lsvlkehkdivrfl.vqiddfrfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdiesgrqlkk 127 l+ + eh + vr + + ++ f+s gdd + +w+ + + l+ l+gh++ i + + +++ + i++as d+t+ +w+ +s FUN_001655-T1 44 LERFDEHDGPVRGInFHTNQPLFVSGGDDYKIKIWNYKQKKCLFTLLGHLDYIRTT-------FFHHEYPWIISASDDQTIRIWNWQSRTCTCV 130 6677788888886525677889****************************999643.......334456899***************9988888 PP Beta-prop_WDR41 128 isdfqstvksltvlerldlwlsgg..sdlrvwn 158 ++ + v + + dl +s + +rvw+ FUN_001655-T1 131 LTGHNHYVMCAQFHPSEDLVVSASldQTVRVWD 163 888888888888877777777665114477775 PP == domain 2 score: 12.7 bits; conditional E-value: 0.0001 Beta-prop_WDR41 57 asagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdies 121 +sa+dd ++ +w+ q+ l gh + ++ dl+++as d+tv vwdi FUN_001655-T1 109 ISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFH-------PSEDLVVSASLDQTVRVWDISG 166 79************************9887654333.......45689**************954 PP == domain 3 score: 1.5 bits; conditional E-value: 0.24 Beta-prop_WDR41 313 viayqkkahdsnvlhiaklpnrq.lvscsedgsvriwelrekkkssa 358 ++ + + hd v ++a p +vs ++d v++w +++ k ++ FUN_001655-T1 198 IVKHVLEGHDRGVNWVAFHPTMPlIVSGADDRQVKLWRMNDSKAWEV 244 666777899*******999987626899***********99876655 PP == domain 4 score: 5.6 bits; conditional E-value: 0.014 Beta-prop_WDR41 320 ahdsnvlhiaklpnrqlv.scsedgsvriwelrekk 354 h nv ++ p ++l+ s sed s+r+w++++++ FUN_001655-T1 249 GHYNNVSCVMFHPRQELIlSNSEDKSIRVWDMSKRT 284 678888888877777754399999999999999875 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.22 1.2e+02 110 183 .. 51 123 .. 36 126 .. 0.74 2 ! 12.9 0.8 0.00011 0.062 126 182 .. 109 164 .. 104 171 .. 0.89 3 ! 12.1 0.2 0.0002 0.11 107 152 .. 248 292 .. 188 323 .. 0.52 4 ? 3.8 0.0 0.066 37 112 224 .. 455 558 .. 435 580 .. 0.71 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.22 Beta-prop_Aladin 110 hspvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvwete 183 pv ++++++ l vs+ d +i +W+ +++++ + + + + +++a+ + r+w+ + FUN_001655-T1 51 DGPVRGINFHTNQPLFVSG-GDDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQ 123 3699999999998888887.5799*******9999975433333344444556666789999999999999876 PP == domain 2 score: 12.9 bits; conditional E-value: 0.00011 Beta-prop_Aladin 126 vsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvwet 182 +sas d++i +W+ + +t++ + ++ v+ +++ p+++ +++a+ + rvw++ FUN_001655-T1 109 ISAS-DDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164 5555.68999************9999999**************************97 PP == domain 3 score: 12.1 bits; conditional E-value: 0.0002 Beta-prop_Aladin 107 rpghspvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvg 152 r +++ v +v ++p+ +l++s s d+si vWd++k+t v+ r FUN_001655-T1 248 RGHYNNVSCVMFHPRQELILSNS-EDKSIRVWDMSKRTGVQTFRRE 292 33456777777777777777766.4777777777777777655533 PP == domain 4 score: 3.8 bits; conditional E-value: 0.066 Beta-prop_Aladin 112 pvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvwetetWtcerWtvlkgrvqaacwsp 204 p ++ ++ +G+lL+ s+ ++dv+++++ L v+ + v ++ ws+d s + ++v + ++ +c + rv++++w FUN_001655-T1 455 PCDMIFYAGTGSLLLRD---TDSVTLFDVQQKRT--LATVKVNKVRYVVWSADMSYVALLG-KHVVAIC-NRKLECLCTIHENIRVKSGAWEE 540 55556666666666642...34678899988876..56666678*********99985544.4555554.45667777777788999999998 PP Beta-prop_Aladin 205 dgsvllfateeepviyslsf 224 +g ++ t+++ + y+l+ FUN_001655-T1 541 NGV--FVYTTSNHIKYALTN 558 864..444556667788776 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.1 0.0 0.00033 0.18 92 175 .. 4 84 .. 1 101 [. 0.88 2 ? 3.4 0.0 0.07 39 137 172 .. 131 165 .. 101 179 .. 0.79 3 ! 7.8 0.1 0.0032 1.8 114 183 .. 224 292 .. 210 306 .. 0.76 4 ? -0.1 0.0 0.8 4.5e+02 15 41 .. 543 569 .. 536 579 .. 0.87 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00033 Beta-prop_SPT8 92 eyepkvspvyslevnkealfllsGldnGgitlqgvrydeGriahylkakhsnvvnilrlnstedkflsgswdkkilewdlntgk 175 ++e k + v ++ + ++l+ l+nG+i+l r ++++ + + h +v +++ +++ f+sg+ d ki w+ + +k FUN_001655-T1 4 KFETKSARVKGIAFHPTRPWVLASLHNGVIQLWDYR--MCTLLERFDE-HDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKK 84 567788889999999999************998755..578999**95.*****************************988766 PP == domain 2 score: 3.4 bits; conditional E-value: 0.07 Beta-prop_SPT8 137 lkakhsnvvnilrlnstedkflsgswdkkilewdln 172 l ++h++ v ++ +ed ++s+s d+ + wd+ FUN_001655-T1 131 L-TGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165 3.479999**************************87 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0032 Beta-prop_SPT8 114 sGldnGgitlqgvrydeGriahylkakhsnvvnilrlnstedkflsgswdkkilewdlntgkvineykga 183 sG d+ ++l + ++ + + +h n v+ + + ++ +ls s dk i wd+ + ++ ++ + FUN_001655-T1 224 SGADDRQVKLWRMNDSKAWEVDTCR-GHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRE 292 5555555555555544444455566.6*******************************988888888765 PP == domain 4 score: -0.1 bits; conditional E-value: 0.8 Beta-prop_SPT8 15 vnalavskglkylflGGndGyirkfdl 41 v + + s+ +ky ++ G+ G ir dl FUN_001655-T1 543 VFVYTTSNHIKYALTNGDHGIIRTLDL 569 66789999****************998 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 9.6e-05 0.054 58 134 .. 7 83 .. 2 90 .. 0.94 2 ? 2.7 0.5 0.1 57 68 131 .. 101 164 .. 95 171 .. 0.85 3 ! 11.8 0.2 0.00018 0.1 39 138 .. 186 287 .. 180 296 .. 0.89 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 9.6e-05 Beta-prop_IFT140_1st 58 ersvqvtvlsWHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWkldqr 134 ++s +v ++ HPt++ + + +G + ++ + +l e + h+ + +++ +n +vsg + +W+ q+ FUN_001655-T1 7 TKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQK 83 57889999****************************************************************99887 PP == domain 2 score: 2.7 bits; conditional E-value: 0.1 Beta-prop_IFT140_1st 68 WHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvvWkl 131 H + + ++ + ++ + ++n q++++t + + h++ +++ ++ + +vs+ ++ vW + FUN_001655-T1 101 FHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164 5667777777888889999999999999999999999999999999999999999999999965 PP == domain 3 score: 11.8 bits; conditional E-value: 0.00018 Beta-prop_IFT140_1st 39 gGsvdlyleegekvedakiersvqvtvlsWHPtkkilavgwesGevlvlneqdkeltelpk..lhkaeitvlewssngsrLvsgdksGv 125 G +l+ ++ v+++ + v ++ HPt ++++ g ++ +v ++ +d + e+++ h +++++ + + ++s + + FUN_001655-T1 186 PGHTELFGQSDAIVKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMNDSKAWEVDTcrGHYNNVSCVMFHPRQELILSNSEDKS 274 57788888888888998888999999***************************9999887633799*********************** PP Beta-prop_IFT140_1st 126 lvvWkldqrGrlq 138 + vW + +r +q FUN_001655-T1 275 IRVWDMSKRTGVQ 287 *****99997776 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 8.5e-05 0.047 241 310 .. 21 88 .. 3 95 .. 0.83 2 ? 5.9 0.1 0.013 7.1 244 303 .. 108 165 .. 96 182 .. 0.77 3 ? 5.7 0.0 0.015 8.1 251 310 .. 229 288 .. 204 295 .. 0.80 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 8.5e-05 Beta-prop_DCAF4 241 eqlllaadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllrt 310 +la+ G i+lwd r +++++ h + +h+n + l v+ G d +iw k+ + l t FUN_001655-T1 21 RPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTN--QPLFVSGGDDYKIKIWNYKQKKCLFT 88 5578899999********************998888777776..57999************999888776 PP == domain 2 score: 5.9 bits; conditional E-value: 0.013 Beta-prop_DCAF4 244 llaadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslk 303 +++a +i++w+ ++ c Gh+ + + e l+v++ d r+w + FUN_001655-T1 108 IISASDDQTIRIWNWQSRTCTCVLTGHNHYV--MCAQFHPSEDLVVSASLDQTVRVWDIS 165 4555556789999999999999999*96544..44556677889999999999****875 PP == domain 3 score: 5.7 bits; conditional E-value: 0.015 Beta-prop_DCAF4 251 Gkiklwdlratkc..vkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllrt 310 ++klw + +k+ v +Gh n+ +++ +h ++e l+++ +d r+w + + + ++t FUN_001655-T1 229 RQVKLWRMNDSKAweVDTCRGHYNNVSCVMFHPRQE--LILSNSEDKSIRVWDMSKRTGVQT 288 589*****99997558899********999987654..888999999*****9987665555 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 2.6 1.4e+03 122 157 .. 49 84 .. 32 114 .. 0.64 2 ? 0.2 0.0 0.67 3.7e+02 182 213 .. 86 117 .. 70 130 .. 0.86 3 ! 11.7 0.1 0.00022 0.12 121 211 .. 132 229 .. 108 240 .. 0.77 4 ! 10.0 0.1 0.00073 0.4 97 160 .. 222 287 .. 221 319 .. 0.81 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 2.6 NBCH_WD40 122 qhkdvvscvavtsdgsvlatGsydttvmvwevlrar 157 +h v + ++ + ++G d + +w+ +++ FUN_001655-T1 49 EHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKK 84 566666666666666666777777777777655443 PP == domain 2 score: 0.2 bits; conditional E-value: 0.67 NBCH_WD40 182 lhilcGhddiitclfvsveldivisGskdgtc 213 l l Gh d i + f e +is s d t FUN_001655-T1 86 LFTLLGHLDYIRTTFFHHEYPWIISASDDQTI 117 5678999999999999**********999986 PP == domain 3 score: 11.7 bits; conditional E-value: 0.00022 NBCH_WD40 121 rqhkdvvscvavtsdgsvlatGsydttvmvwevlrarssekrvrntqtelsrkd....vviaek...plhilcGhddiitclfvsveldivisGsk 209 h+ v c + ++++ s d tv vw+++ r+++ ++ + + k+ + ++ h+l Ghd + ++ + +++sG+ FUN_001655-T1 132 TGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKTVAPGTSGLDEHLKSpghtELFGQSdaiVKHVLEGHDRGVNWVAFHPTMPLIVSGAD 227 5699999**************************9888777665544444444432222333332111469************************99 PP NBCH_WD40 210 dg 211 d FUN_001655-T1 228 DR 229 86 PP == domain 4 score: 10.0 bits; conditional E-value: 0.00073 NBCH_WD40 97 iscGnwensfqvislsdGrl..vqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlrarsse 160 i G + ++ ++d + v + r h + vscv +++ + s d ++ vw++++ + + FUN_001655-T1 222 IVSGADDRQVKLWRMNDSKAweVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQ 287 6667777778888888887544899*********************************99765544 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.053 30 13 86 .. 11 85 .. 1 98 [. 0.80 2 ? 3.2 0.1 0.084 47 47 112 .. 88 155 .. 83 173 .. 0.68 3 ! 10.6 0.0 0.00047 0.26 12 91 .. 208 291 .. 189 324 .. 0.76 4 ? -2.5 0.0 4.6 2.6e+03 115 159 .. 475 518 .. 448 537 .. 0.64 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.053 Beta-prop_IFT122_1st 13 cindiafkpdgtqlilaa.gsrllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegi 86 ++ iaf+p ++ + + ++d tll+ + h v + + + f sg d + iw k + FUN_001655-T1 11 RVKGIAFHPTRPWVLASLhNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQKKC 85 56778888877655444313446689999***************************************9987654 PP == domain 2 score: 3.2 bits; conditional E-value: 0.084 Beta-prop_IFT122_1st 47 plkghkdtvycvayakdgkrfasgsadksviiwt..sklegilkythndaiqcvsynpithqlascss 112 l gh d + + ++ + s s d+++ iw s+ + hn + c + p + s+s FUN_001655-T1 88 TLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNwqSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASL 155 56677777777777777777888888888877642266666677778888888888887666665553 PP == domain 3 score: 10.6 bits; conditional E-value: 0.00047 Beta-prop_IFT122_1st 12 hcindiafkpdgtqlilaagsr...llvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiw.tsklegilkyth 91 + +n +af+p ++ a r l + s ++ +gh + v cv + + + s s dks+ +w sk g+ + + FUN_001655-T1 208 RGVNWVAFHPTMPLIVSGADDRqvkLWRMNDSKAWEVDTCRGHYNNVSCVMFHPRQELILSNSEDKSIRVWdMSKRTGVQTFRR 291 568889999988877777776621133445566667889999********999999999999*****99994488888877754 PP == domain 4 score: -2.5 bits; conditional E-value: 4.6 Beta-prop_IFT122_1st 115 fglwspeqksvskhkssskiiccswtndgqylalgmfngiisirn 159 + l+ +qk +k+ + w+ d y+al + + +++i n FUN_001655-T1 475 VTLFDVQQKRTLATVKVNKVRYVVWSADMSYVAL-LGKHVVAICN 518 3455555555555555666666677777777765.2344455555 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.0 0.0012 0.68 59 153 .. 71 166 .. 24 175 .. 0.79 2 ? 0.9 0.0 0.47 2.6e+02 71 150 .. 239 279 .. 197 317 .. 0.60 3 ? 4.5 0.1 0.036 20 58 141 .. 470 548 .. 419 569 .. 0.60 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.0012 Beta-prop_WDR19_1st 59 ksslvllwdantkktskldtglkdkltfllWskkspiLavGtskGnlllYnkktskkipilGkHskkItcgaws.kenlLalgseDktlt 147 + ++ +w+ ++kk g d + + ++ p ++ +++ ++ ++n +++ + +l H++ ++c++++ +e+l++ +s D+t+ FUN_001655-T1 71 DDYKIKIWNYKQKKCLFTLLGHLDYIRTTFFHHEYPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHpSEDLVVSASLDQTVR 160 5566778888888777777777777888888888888888888899999************************967788888999****9 PP Beta-prop_WDR19_1st 148 isnaeG 153 + +++G FUN_001655-T1 161 VWDISG 166 999988 PP == domain 2 score: 0.9 bits; conditional E-value: 0.47 Beta-prop_WDR19_1st 71 kktskldtglkdkltfllWskkspiLavGtskGnlllYnkktskkipilGkHskkItcgawskenlLal.gseDktltisn 150 +k+ ++dt H +++ c ++ + L+l seDk++ + + FUN_001655-T1 239 SKAWEVDT----------------------------------------CRGHYNNVSCVMFHPRQELILsNSEDKSIRVWD 279 33333333........................................333444444544443322222134455444444 PP == domain 3 score: 4.5 bits; conditional E-value: 0.036 Beta-prop_WDR19_1st 58 eksslvllwdantkktskldtglkdkltfllWskkspiLavGtskGnlllYnkktskkipilGkHskkItcgawskenlLalgs 141 +++++v+l+d+++k+t t +k+ +++Ws + +++a+ k +++ n+k + +i + ++ +gaw+++++++ ++ FUN_001655-T1 470 RDTDSVTLFDVQQKRTL--ATVKVNKVRYVVWSADMSYVALL-GKHVVAICNRKLECLCTIH--ENIRVKSGAWEENGVFVYTT 548 45667778877766543..33333456778888877777763.3445666666555444442..23466677777777666544 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 1.6 9e+02 211 248 .. 6 42 .. 2 70 .. 0.78 2 ? 0.1 0.0 1.1 5.9e+02 224 248 .. 60 84 .. 42 101 .. 0.83 3 ! 10.7 0.4 0.00064 0.36 227 273 .. 105 151 .. 95 155 .. 0.87 4 ? 2.8 0.0 0.17 94 227 250 .. 147 170 .. 146 176 .. 0.82 5 ! 7.9 0.0 0.0045 2.5 211 272 .. 204 266 .. 194 271 .. 0.79 6 ? 6.6 0.0 0.011 6.3 211 263 .. 248 299 .. 244 306 .. 0.79 7 ? -0.1 0.0 1.3 7e+02 175 199 .. 423 447 .. 331 455 .. 0.64 8 ? -0.6 0.2 1.8 1e+03 71 143 .. 482 554 .. 472 565 .. 0.71 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 1.6 Beta-prop_RIG_2nd 211 saekasitsvkwsnansnlllsfsidgkvkvWdleepe 248 + ++a+++ +++ +++ +l s + +g +++Wd + + FUN_001655-T1 6 ETKSARVKGIAFHPTRPWVLASLH-NGVIQLWDYRMCT 42 567899999999999999999977.5*******87655 PP == domain 2 score: 0.1 bits; conditional E-value: 1.1 Beta-prop_RIG_2nd 224 nansnlllsfsidgkvkvWdleepe 248 ++n+ l++s + d k+k+W+ ++++ FUN_001655-T1 60 HTNQPLFVSGGDDYKIKIWNYKQKK 84 45678999*9***********9987 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00064 Beta-prop_RIG_2nd 227 snlllsfsidgkvkvWdleepekeeltitykcpmlcglFlPtdeniv 273 ++s s d ++++W+ ++ + + +++ ++ ++c+ F P+++ +v FUN_001655-T1 105 YPWIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVV 151 556899999********************************987766 PP == domain 4 score: 2.8 bits; conditional E-value: 0.17 Beta-prop_RIG_2nd 227 snlllsfsidgkvkvWdleepeke 250 ++l++s s+d +v+vWd++ +k+ FUN_001655-T1 147 EDLVVSASLDQTVRVWDISGLRKK 170 57899************9876665 PP == domain 5 score: 7.9 bits; conditional E-value: 0.0045 Beta-prop_RIG_2nd 211 saekasitsvkwsnansnlllsfsidgkvkvWdleepek..eeltitykcpmlcglFlPtdeni 272 + + +++v++ ++ l++s d +vk+W +++++ + ++ + c +F P +e i FUN_001655-T1 204 EGHDRGVNWVAFHPTM-PLIVSGADDRQVKLWRMNDSKAweVDTCRGHYNNVSCVMFHPRQELI 266 5677788888887765.5788989999**********983245666799**********99865 PP == domain 6 score: 6.6 bits; conditional E-value: 0.011 Beta-prop_RIG_2nd 211 saekasitsvkwsnansnlllsfsidgkvkvWdleepekeeltitykcpmlcg 263 + + +++++v + +++ +l+ls s d +++vWd+++ + ++ + +++ FUN_001655-T1 248 RGHYNNVSCVMFHPRQ-ELILSNSEDKSIRVWDMSKRTGVQTFRREHDRFWVA 299 5677899999999986.588999************999877776666666666 PP == domain 7 score: -0.1 bits; conditional E-value: 1.3 Beta-prop_RIG_2nd 175 plesnklAvvandkvivilefkeee 199 +++n +Av +++++ i ++k+e FUN_001655-T1 423 WVARNRFAVLDRTHTLLIKNLKNEV 447 3466777777777777777777664 PP == domain 8 score: -0.6 bits; conditional E-value: 1.8 Beta-prop_RIG_2nd 71 vktllrkvlkkeiYslvWkkkylyvvsnrelavydakkkkkeatllkkiervslvsvrdslLlvgtedGalql 143 +k++l++v +++ +vW+ ++ yv ++ +v ++k + +++++ rv + +++++ +v t + ++++ FUN_001655-T1 482 QKRTLATVKVNKVRYVVWSADMSYVALLGKHVVAICNRKLECLCTIHENIRVKSGAWEENGVFVYTTSNHIKY 554 4566777777777778888888887777777776677777777777777777777777777777777777765 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.3 0.0 0.0062 3.4 15 90 .. 7 82 .. 1 87 [. 0.93 2 ? 0.5 0.0 0.71 4e+02 31 90 .. 107 166 .. 94 185 .. 0.82 3 ? 3.9 0.0 0.067 37 39 149 .. 187 293 .. 184 302 .. 0.86 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0062 Beta-prop_HPS5 15 rsskRvkytclavsrkflaLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelni 90 +s+Rvk ++ +r ++ +G + +++ + ll+++ +++g++ + + +++ l+ ++++ ++ +++ ++ FUN_001655-T1 7 TKSARVKGIAFHPTRPWVLASLHNGVIQLWDYRMCTLLERFDEHDGPVRGINFHTNQPLFVSGGDDYKIKIWNYKQ 82 4899********************************************************************9875 PP == domain 2 score: 0.5 bits; conditional E-value: 0.71 Beta-prop_HPS5 31 flaLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelni 90 +++ s ++ i++ ++ + +lt ++ + + + p+edlv a+ + v v+++ FUN_001655-T1 107 WIISASDDQTIRIWNWQSRTCTCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISG 166 5666666677888888888899999*******************************9864 PP == domain 3 score: 3.9 bits; conditional E-value: 0.067 Beta-prop_HPS5 39 GgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsv 133 G +f ++ + + ++l ++ + va+ p+ l+ ++++ +v ++ +n +k+ ++ + h + +v++++ + +++ + + e ++ v FUN_001655-T1 187 GHTELFGQSDAIVKHVLEGHDRGVNWVAFHPTMPLIVSGADDRQVKLWRMN---DSKAWEVDTCRGHYN-NVSCVMFHPRQELILSNSEDKSIRV 277 66778888888899999999*99***************************9...889999999999976.6999999999999999999999999 PP Beta-prop_HPS5 134 tklssskasalfkvsv 149 ++s+++ + f+ + FUN_001655-T1 278 WDMSKRTGVQTFRREH 293 9999888877777655 PP >> Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.2 1.1e+02 195 211 .. 72 88 .. 60 94 .. 0.90 2 ? 2.0 0.5 0.17 92 185 210 .. 104 129 .. 95 134 .. 0.83 3 ? 7.3 0.0 0.0039 2.2 181 268 .. 141 239 .. 130 248 .. 0.60 4 ? 2.2 0.0 0.14 78 177 210 .. 255 287 .. 246 294 .. 0.83 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.2 Beta-prop_Nup120_160 195 DhkLRvWslktgkcvat 211 D k+++W++k++kc++t FUN_001655-T1 72 DYKIKIWNYKQKKCLFT 88 899***********997 PP == domain 2 score: 2.0 bits; conditional E-value: 0.17 Beta-prop_Nup120_160 185 ddtllftvclDhkLRvWslktgkcva 210 ++ +++ + D ++R+W+ ++++c + FUN_001655-T1 104 EYPWIISASDDQTIRIWNWQSRTCTC 129 5566888999************9976 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0039 Beta-prop_Nup120_160 181 ves.eddtllftvclDhkLRvWslktg..kcvat.idlleerdpqesrkkltldpsqsnllkvv.gsdgglylvvty.......sppse 257 +++ + ++l+++ +lD ++RvW+++ k va ++ l+e + + ++ +++s++ + +v+ g+d+g v++ s ++ FUN_001655-T1 141 AQFhPSEDLVVSASLDQTVRVWDISGLrkKTVAPgTSGLDEHLK-SPGHTELFGQSDAIVKHVLeGHDRGVNWVAFHptmplivSGADD 228 3333799***************9874311333332444444444.33333366666666666667444444444444444555577788 PP Beta-prop_Nup120_160 258 gqFkfwkvkpg 268 q k+w+++++ FUN_001655-T1 229 RQVKLWRMNDS 239 88888887665 PP == domain 4 score: 2.2 bits; conditional E-value: 0.14 Beta-prop_Nup120_160 177 avavveseddtllftvclDhkLRvWslktgkcva 210 + +++ + ++l+++ + D+ +RvW++++++ v FUN_001655-T1 255 SCVMFH-PRQELILSNSEDKSIRVWDMSKRTGVQ 287 445555.8999*****************998776 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.032 18 260 310 .. 113 165 .. 96 171 .. 0.57 2 ? 5.1 0.0 0.026 14 265 309 .. 235 280 .. 208 303 .. 0.65 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.032 WDR90_beta-prop_4th 260 aerllrlvdcasgtaq.dfaghddsvqlcrfspsgkllftaayse.ilvweva 310 +++ +r+ + +s t +gh+ v +f ps l+++a+ ++ + vw++ FUN_001655-T1 113 DDQTIRIWNWQSRTCTcVLTGHNHYVMCAQFHPSEDLVVSASLDQtVRVWDIS 165 34444555555544331345666666666666666666666654314466554 PP == domain 2 score: 5.1 bits; conditional E-value: 0.026 WDR90_beta-prop_4th 265 rlvdcasgtaqdfaghddsvqlcrfspsgkllftaays.eilvwev 309 r+ d+++ +++ gh + v f p +l+++ + + i vw++ FUN_001655-T1 235 RMNDSKAWEVDTCRGHYNNVSCVMFHPRQELILSNSEDkSIRVWDM 280 3445555566666677777777777777777666654314666665 PP >> Aa-Ago_N Ago, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00064 0.36 21 43 .. 277 300 .. 255 319 .. 0.76 2 ? -2.3 0.1 8.8 4.9e+03 14 25 .. 488 499 .. 477 501 .. 0.80 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00064 Aa-Ago_N 21 rwrvflqtglptfrre.defwcag 43 w + +tg+ tfrre d fw a FUN_001655-T1 277 VWDMSKRTGVQTFRREhDRFWVAA 300 3888999********9688**996 PP == domain 2 score: -2.3 bits; conditional E-value: 8.8 Aa-Ago_N 14 keklnkvrwrvf 25 k+nkvr+ v+ FUN_001655-T1 488 TVKVNKVRYVVW 499 5699****9885 PP >> TPR_IFT80_172 IFT80/172/WDR35/WDR19 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.0016 0.88 2 55 .. 677 730 .. 676 764 .. 0.87 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0016 TPR_IFT80_172 2 WacLaamalaakelntaevayaaieevdkvqyiqyikelpskearnAelalfsr 55 W L a al++ + ++ e+ay ++ dk++++ i +k ++ ++a ++ FUN_001655-T1 677 WERLGAAALTQGNHQVVEMAYQRTKNFDKLSFLYLITGNLEKLGKMTKIAEIRK 730 999*****************************9999988888777777765555 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.1 5.4 3e+03 2 25 .. 675 698 .. 654 705 .. 0.73 2 ? -0.3 0.0 6.8 3.8e+03 7 25 .. 927 945 .. 925 948 .. 0.86 3 ? 6.7 0.0 0.037 20 5 34 .. 1107 1136 .. 1105 1155 .. 0.88 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 5.4 TPR_14 2 eawlalarallalGdpdeAlelle 25 ++w +l++a l +G+++ + +++ FUN_001655-T1 675 ACWERLGAAALTQGNHQVVEMAYQ 698 457777777777777776666665 PP == domain 2 score: -0.3 bits; conditional E-value: 6.8 TPR_14 7 larallalGdpdeAlelle 25 la ++ +G ++ A++ll FUN_001655-T1 927 LAVDHVSAGSFESAMRLLH 945 7777899*********996 PP == domain 3 score: 6.7 bits; conditional E-value: 0.037 TPR_14 5 lalarallalGdpdeAlelleralaldPdd 34 + +++++++l++++ A+ ++r+l+l P FUN_001655-T1 1107 RTAVNLFFKLKNFKTAASFARRLLELGPRP 1136 6789999********************984 PP >> Beta-prop_IP5PC_F IP5P C-F beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.065 36 77 148 .. 65 131 .. 48 144 .. 0.69 2 ? 2.7 0.1 0.12 66 77 138 .. 221 279 .. 209 281 .. 0.74 3 ? 5.1 0.0 0.022 12 65 112 .. 253 302 .. 247 312 .. 0.80 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.065 Beta-prop_IP5PC_F 77 lvwsGhkdGkirswkmdqssddtsfkeglswqahrgpvls.lvissyGdlwsgsegGvikvwpwesiekslsl 148 l sG d ki+ w +q++ ++ h + + + y + s+s++ +i++w w+s + l FUN_001655-T1 65 LFVSGGDDYKIKIWNYKQKK------CLFTLLGHLDYIRTtFFHHEYPWIISASDDQTIRIWNWQSRTCTCVL 131 66677777777777766553......3344445555554314456799999*************997665555 PP == domain 2 score: 2.7 bits; conditional E-value: 0.12 Beta-prop_IP5PC_F 77 lvwsGhkdGkirswkmdqssddtsfkeglswqahrgpvlslvissyGd.lwsgsegGvikvwp 138 l+ sG d +++ w+m+ s ++ e + + h +v +++ + + s se+ +i+vw FUN_001655-T1 221 LIVSGADDRQVKLWRMNDS---KA-WEVDTCRGHYNNVSCVMFHPRQElILSNSEDKSIRVWD 279 7889999999999998643...33.45667788888888877776665257889999999995 PP == domain 3 score: 5.1 bits; conditional E-value: 0.022 Beta-prop_IP5PC_F 65 ptlclvvdegsklvwsGhkdGkirswkmdqssddtsfkegl..swqahrg 112 ++ c++ + l+ s d ir w m + + ++f+ + w a FUN_001655-T1 253 NVSCVMFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRREHdrFWVAAAH 302 678****************************9999998543114555555 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.3 0.021 11 109 138 .. 132 162 .. 48 167 .. 0.62 2 ? 4.9 0.1 0.025 14 109 141 .. 132 165 .. 125 185 .. 0.83 3 ? 2.5 0.1 0.14 78 124 173 .. 220 269 .. 203 381 .. 0.62 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.021 Beta-prop_DCAF12 109 kghkdwifaiaw.lsdtvavsGsrdgtlalw 138 gh++++++ ++ s+ ++vs s d t+ +w FUN_001655-T1 132 TGHNHYVMCAQFhPSEDLVVSASLDQTVRVW 162 3455554444331355555555555555555 PP == domain 2 score: 4.9 bits; conditional E-value: 0.025 Beta-prop_DCAF12 109 kghkdwifaiaw.lsdtvavsGsrdgtlalwrvd 141 gh++++++ ++ s+ ++vs s d t+ +w + FUN_001655-T1 132 TGHNHYVMCAQFhPSEDLVVSASLDQTVRVWDIS 165 6899998877652599***************986 PP == domain 3 score: 2.5 bits; conditional E-value: 0.14 Beta-prop_DCAF12 124 tvavsGsrdgtlalwrvdpdklnasialkneaelpvyahirPkeleaiPk 173 ++vsG+ d + lwr++ k + + + + + + +P++ + + FUN_001655-T1 220 PLIVSGADDRQVKLWRMNDSKAWEVDTCRGHYNNVSCVMFHPRQELILSN 269 46789999999999998876654444444444444444555555444433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1225 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 898 (0.0351537); expected 510.9 (0.02) Passed bias filter: 753 (0.0294774); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 47 (0.00183989); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 46 [number of targets reported over threshold] # CPU time: 0.66u 0.39s 00:00:01.05 Elapsed: 00:00:00.45 # Mc/sec: 10874.78 // Query: FUN_001656-T1 [L=318] Description: FUN_001656 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-27 96.0 0.2 1.2e-25 90.6 0.2 2.1 2 adh_short short chain dehydrogenase 7.9e-16 58.8 0.0 7.2e-15 55.7 0.0 2.0 1 adh_short_C2 Enoyl-(Acyl carrier protein) reductase 1.2e-06 29.1 0.0 2.3e-06 28.2 0.0 1.5 1 KR KR domain 1e-05 25.6 0.0 1.3e-05 25.3 0.0 1.2 1 Epimerase NAD dependent epimerase/dehydratase family 0.0039 17.6 0.1 0.0085 16.5 0.1 1.6 1 3HCDH_N 3-hydroxyacyl-CoA dehydrogenase, NAD binding d 0.0073 16.2 0.0 0.22 11.3 0.0 2.3 1 DUF1776 Fungal family of unknown function (DUF1776) 0.0078 16.2 0.0 0.013 15.5 0.0 1.4 1 GDP_Man_Dehyd GDP-mannose 4,6 dehydratase ------ inclusion threshold ------ 0.054 13.2 0.0 0.082 12.6 0.0 1.2 1 Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase Domain annotation for each model (and alignments): >> adh_short short chain dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.6 0.2 3.9e-29 1.2e-25 3 137 .. 43 177 .. 41 185 .. 0.97 2 ? 3.4 0.0 0.021 66 141 189 .. 195 241 .. 191 245 .. 0.88 Alignments for each domain: == domain 1 score: 90.6 bits; conditional E-value: 3.9e-29 adh_short 3 vlvtGassGiGraiakelakeGakvvlvdrseekleevakelkee..gekalaiqvDvtdeeevkalvekaveklgkldvLvnNAGitksgpfsel 96 ++tGa sGiG+++a +ak+Ga+v +v rse + ee+ ke+ e+ ++k+ +D+++ ++v ++ve+ + ++l+vL+nNAG ++++ e+ FUN_001656-T1 43 FMITGANSGIGKDAAMYFAKKGATVHMVCRSETRGEEARKEISETagNDKIKLHILDMSQPKKVWQFVETFTSTNETLNVLINNAGC--MVNTREV 136 68*******************************************99999*************************************..899**** PP adh_short 97 seeewervievNltgvfnltravlpamlkrkkGrIvnvsSv 137 +e+ +e+ +++N g++ lt ++p++lk+++ r+++vsS FUN_001656-T1 137 DEDGVEKNFATNTLGTYILTSGLIPHLLKQESPRVITVSSG 177 ****************************************6 PP == domain 2 score: 3.4 bits; conditional E-value: 0.021 adh_short 141 vgvaglsaYsASKaavigltrslakelapkgirvnavaPGvvkTdmake 189 +++ g+ aY+ K + +t++la+ +++ i ++++PG +T+ +++ FUN_001656-T1 195 NPFDGTMAYAQNKRQQVIMTEKLAEKHKE--IFFSSMHPGWADTPAVRS 241 68889999****************98877..9************98876 PP >> adh_short_C2 Enoyl-(Acyl carrier protein) reductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.7 0.0 2.3e-18 7.2e-15 1 180 [. 47 238 .. 47 268 .. 0.75 Alignments for each domain: == domain 1 score: 55.7 bits; conditional E-value: 2.3e-18 adh_short_C2 1 GaanesgIgwaiAkalaeeGaevvltdlneea.kkrveelaeelgae.v..lecDVtdeeqvealveevkekfgklDilvnnagiapklkgpfldt 92 Ga sgIg+ +A +a++Ga+v ++ ++e + +++ +e+ e g++ + +D +++++v ++ve+ +++ ++l++l+nnag + + + ++ FUN_001656-T1 47 GAN--SGIGKDAAMYFAKKGATVHMVCRSETRgEEARKEISETAGNDkIklHILDMSQPKKVWQFVETFTSTNETLNVLINNAGCMVN----TREV 136 666..***************************8999999999999776676889*********************************9....779* PP adh_short_C2 93 sredfdkaldvnlyslfalakaalp.lmkeg.Gsivtlssvgaerv...v.....pnyn......aygaaKaalealtrylAaelgpkgiRvNavs 172 ++++++k +++n+ +++ l+ ++p l+k++ +++t+ss g ++ + ++ n ay+ K + +t lA + + i + + FUN_001656-T1 137 DEDGVEKNFATNTLGTYILTSGLIPhLLKQEsPRVITVSSGGMLVMkldIkdlqfEKLNpfdgtmAYAQNKRQQVIMTEKLAEKHKE--IFFSSMH 230 *************************75555568899998876543311111111111111112335666666666666666665544..6666666 PP adh_short_C2 173 pgpikTla 180 pg+ +T+a FUN_001656-T1 231 PGWADTPA 238 66666666 PP >> KR KR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.0 7.1e-10 2.3e-06 2 121 .. 42 157 .. 41 184 .. 0.80 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 7.1e-10 KR 2 tylitGGlGgLGrelarwLaekGarhlvllsrsaaasedaealiaeleergvevkvvacDvsdkdavealleelkaegppikGvihaAgvlqdall 97 t++itG+ g+G+ a + a+kGa+ + ++ rs++ e+a+++i+e + + ++k+ +D s++++v + +e+++ ++++++ i+ Ag + ++ FUN_001656-T1 42 TFMITGANSGIGKDAAMYFAKKGAT-VHMVCRSETRGEEARKEISETAG-NDKIKLHILDMSQPKKVWQFVETFTSTNETLNVLINNAGCMVNT-- 133 689********************85.45555665688888889998777.5599***********************************98765.. PP KR 98 eemtaedleevlapKvkGawnLhe 121 e++++ +e+ +a G+ L FUN_001656-T1 134 REVDEDGVEKNFATNTLGTYILTS 157 577788888888877777777765 PP >> Epimerase NAD dependent epimerase/dehydratase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 4e-09 1.3e-05 2 169 .. 44 231 .. 43 272 .. 0.80 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 4e-09 Epimerase 2 lVtGatGfiGsalveallekgyevigldrrssasntarladl........elveldltdkd....alekllkev.kpdavihlAa..vsgvaasle 82 ++tGa+ iG+ + ++++kg +v+ + r ++ ++ar++ +l+ ld+++++ +e + +++ ++ i+ A+ v + ++ + FUN_001656-T1 44 MITGANSGIGKDAAMYFAKKGATVHMVCRSETRGEEARKEISetagndkiKLHILDMSQPKkvwqFVETFTSTNeTLNVLINNAGcmVNTREVDED 139 69****************************99999988876699****************944433334444445677888887777777777777 PP Epimerase 83 dpedtieanvlgtlnlleaar....kagvkrfvfasssevYGkgaeip..qeettetgplapnspYaaaKlaaerlveayaaey.glravilrl 169 e+ + +n+lgt+ l + + k++ r++ +ss + + +i q e++ p+ + +Ya K+ ++e++a+++ ++++ ++ + FUN_001656-T1 140 GVEKNFATNTLGTYILTSGLIphllKQESPRVITVSSGGMLVMKLDIKdlQFEKL--NPFDGTMAYAQNKRQQVIMTEKLAEKHkEIFFSSMHP 231 778888899999988877666333366666********99999999742444444..799***********************98888877665 PP >> 3HCDH_N 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.1 2.7e-06 0.0085 10 77 .. 52 120 .. 44 145 .. 0.87 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 2.7e-06 3HCDH_N 10 mGagiaavfasagleVvlvdiseealekalekiekslek.lvekgklkeeeveellarisittdleeav 77 +G+ a+ fa++g +V++v +se + e+a+++i++++ + +++ + l+ ++ +++ + +++ t+++e FUN_001656-T1 52 IGKDAAMYFAKKGATVHMVCRSETRGEEARKEISETAGNdKIKLHILDMSQPKKVWQFVETFTSTNETL 120 899*******************************97655155666677899999999999999888765 PP >> DUF1776 Fungal family of unknown function (DUF1776) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.0 7e-05 0.22 51 152 .. 92 176 .. 48 192 .. 0.61 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7e-05 DUF1776 51 dIrslsldd.atssieasleeflqsletpvvpfpgakphvlrLkgvilvPslsyptgpieniplssweselnerlleylltlqallpllksraqka 145 +I+ +ld +++++++ +e+f ++ et L v++ + + ++ ++ +e+ + ++ l +++++++l+p+l + ++++ FUN_001656-T1 92 KIKLHILDMsQPKKVWQFVETFTSTNET--------------L-NVLINNAGCMVNT--REVDEDGVEKNFATNTLGTYILTSGLIPHLLK-QESP 169 4555555544444444444444444443..............2.2333334444444..6889999*********************9986.6889 PP DUF1776 146 kiilvnp 152 ++i v+ FUN_001656-T1 170 RVITVSS 176 9998876 PP >> GDP_Man_Dehyd GDP-mannose 4,6 dehydratase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 4.1e-06 0.013 1 75 [. 44 114 .. 44 229 .. 0.62 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 4.1e-06 GDP_Man_Dehyd 1 LiTGitGqiGsylaelLlekgyevhgivrrsssfntgrlehlkkdpkeeleenlklhkgDltDseslerllkevk 75 +iTG + iG a ++ +kg +vh ++r +++ + +r e ++ ++++klh D++ +++ + +++ + FUN_001656-T1 44 MITGANSGIGKDAAMYFAKKGATVHMVCRSETRGEEARKEI-SET---AGNDKIKLHILDMSQPKKVWQFVETFT 114 69**************************9999888666554.332...35689************9999888763 PP >> Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 2.6e-05 0.082 166 203 .. 41 80 .. 23 106 .. 0.81 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 2.6e-05 Pyr_redox_3 166 kvvViGgknSav..DaAlelvkkgaeVtvltrgselekee 203 ++ i g nS++ DaA+ ++kkga+V+++ r++++ +e FUN_001656-T1 41 RTFMITGANSGIgkDAAMYFAKKGATVHMVCRSETRGEEA 80 44556677898766******************99776653 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (318 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 978 (0.0382854); expected 510.9 (0.02) Passed bias filter: 753 (0.0294774); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3118.39 // Query: FUN_001657-T1 [L=304] Description: FUN_001657 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-13 51.2 0.0 2.3e-13 50.8 0.0 1.2 1 C2 C2 domain 1.6e-12 47.3 0.0 2.7e-12 46.6 0.0 1.4 1 CUE CUE domain ------ inclusion threshold ------ 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 UBA UBA/TS-N domain 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 UBA_4 UBA-like domain Domain annotation for each model (and alignments): >> C2 C2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.8 0.0 3.6e-17 2.3e-13 1 104 [] 85 186 .. 85 186 .. 0.92 Alignments for each domain: == domain 1 score: 50.8 bits; conditional E-value: 3.6e-17 C2 1 gkLevkvieaknLpkkdkkgksdpyvkvklkdgkqkkkTkvv.kktlnPvWnetftfevpeleeevLeieVydkdrlskddflGeveiplse.lds 94 g+L+++v +ak ++ + + +dpy+++++ g++++++ + + + nP+Wn+ + ++vpe +++ +e++d++ +s d+ + + ip++e + + FUN_001657-T1 85 GRLSITVQQAKLAKNY-GVTRMDPYCRIRV--GNHVFESTTAyNGSKNPRWNKLMSIPVPE-GVKEIYVEIFDERAFSMDERIAWGLIPIKEeVFD 176 689*******955555.8899*********..9999988888577789*************.******************************9*** PP C2 95 geeaegwyel 104 ge + wy+l FUN_001657-T1 177 GETLDDWYSL 186 ********87 PP >> CUE CUE domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.6 0.0 4.2e-16 2.7e-12 8 42 .] 268 302 .. 261 302 .. 0.94 Alignments for each domain: == domain 1 score: 46.6 bits; conditional E-value: 4.2e-16 CUE 8 LkemFPdldeevIravLeasngnvEaainaLLegs 42 Lk+mFP++de+vIr vLeas+g+v+aa+ LL+++ FUN_001657-T1 268 LKDMFPNMDESVIRSVLEASGGDVNAATTHLLSMT 302 9*******************************996 PP >> UBA UBA/TS-N domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 2.6e-05 0.17 9 37 .] 268 298 .. 260 298 .. 0.85 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.6e-05 UBA 9 LveM..GFdreqvreALratgnNverAveyL 37 L +M d++ +r L+a+g++v++A+ L FUN_001657-T1 268 LKDMfpNMDESVIRSVLEASGGDVNAATTHL 298 777878899******************9876 PP >> UBA_4 UBA-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 5e-05 0.32 13 33 .. 275 295 .. 274 298 .. 0.91 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 5e-05 UBA_4 13 adeeeArqfLeasnWdLerAv 33 +de + r+ Leas++d+++A FUN_001657-T1 275 MDESVIRSVLEASGGDVNAAT 295 799****************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (304 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 462 (0.0180857); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3026.18 // Query: FUN_001658-T1 [L=320] Description: FUN_001658 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-51 173.3 0.0 9.5e-51 173.0 0.0 1.1 1 Epimerase NAD dependent epimerase/dehydratase family 2.6e-14 53.9 0.1 1.5e-13 51.4 0.0 1.9 2 GDP_Man_Dehyd GDP-mannose 4,6 dehydratase 1.8e-05 24.4 0.0 5.4e-05 22.9 0.0 1.7 2 RmlD_sub_bind RmlD substrate binding domain 9.1e-05 22.3 0.1 0.015 15.0 0.0 2.9 3 Polysacc_synt_2 Polysaccharide biosynthesis protein ------ inclusion threshold ------ 0.025 14.2 0.1 0.073 12.7 0.0 1.7 2 NAD_binding_4 Male sterility protein Domain annotation for each model (and alignments): >> Epimerase NAD dependent epimerase/dehydratase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 173.0 0.0 1.9e-54 9.5e-51 1 240 [] 7 244 .. 7 244 .. 0.95 Alignments for each domain: == domain 1 score: 173.0 bits; conditional E-value: 1.9e-54 Epimerase 1 ilVtGatGfiGsalveallekg....yevigldrrssasntarladlelveldltdkdalekllkevkpdavihlAa.vsgvaasledpedtiean 91 ilVtG++G++G+a e + + ++i l+++ ++dl+d+++++ +++++kp++vihlAa v+g +l+++ d+++ n FUN_001658-T1 7 ILVTGGSGLVGQAFQEVVATEEkrpdETWIFLSSK---------------DGDLCDAEETKGIFDKHKPTHVIHLAAlVGGLFKNLKYNLDFWRMN 87 8**************9999888888677*******...............********************************************** PP Epimerase 92 vlgtlnlleaarkagvkrfvfasssevYGkgaeip.qeettetgpl.apnspYaaaKlaaerlveayaaey..glravilrlfnvyGpg.rgegfv 182 ++++ n+l+ ++ ++vk+ v + s+++++++++ p +e + ++gp+ +n Ya++K++++ + +ay+++y g+ ++++ ++nvyG++ +++ ++ FUN_001658-T1 88 TKINDNVLHSCHLSKVKKCVSCLSTCIFPDKTTYPiDETMVHNGPPhSSNFGYAYSKRMIDVQNKAYHQQYpdGCLFTSVVPTNVYGKHdNFNLED 183 *********************************8878999999***9999**********************99********************** PP Epimerase 183 srvipalirrilegk....eilllgdgtqrRdflyvdDvaeaillalekpdagekgeiyniG 240 s+v+p li +++ ++ +++++g+g++rR+f+y +D+a++++++++++++ ++ i+ +G FUN_001658-T1 184 SHVLPGLIHKVYLAEkegkPLVVWGTGSPRRQFIYSKDLARLMIWVMREYNEA-DPIILSVG 244 ***********99666677******************************9985.55666665 PP >> GDP_Man_Dehyd GDP-mannose 4,6 dehydratase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.1 5.3e+02 1 18 [. 8 25 .. 8 34 .. 0.84 2 ! 51.4 0.0 3e-17 1.5e-13 57 291 .. 41 287 .. 20 307 .. 0.74 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.1 GDP_Man_Dehyd 1 LiTGitGqiGsylaelLl 18 L+TG++G +G + e FUN_001658-T1 8 LVTGGSGLVGQAFQEVVA 25 8*********99887765 PP == domain 2 score: 51.4 bits; conditional E-value: 3e-17 GDP_Man_Dehyd 57 hkgDltDseslerllkevkpdevynLAAqsh.VdvsfekPeytaetnvlGtlrLLeairelglekkvrfyqaStsEvYGkvqevpqtEttpfy..P 149 +gDl+D+e+ + +++++kp+ v++LAA + ++ ++++++n ++L + +++ + + + ++ + ++ p++Et + P FUN_001658-T1 41 KDGDLCDAEETKGIFDKHKPTHVIHLAALVGgLFKNLKYNLDFWRMNTKINDNVLHSCHLSKVK---KCVSCLSTCIFPDKTTYPIDETMVHNgpP 133 579*************************954477777778888888888888999998776655...5666667789***********95544334 PP GDP_Man_Dehyd 150 ...rsPYaaaKlyaewivvnyresyg..lfavngilfnhesprrgeef....vtrkitravarikagkqeklvlGnldakRdwgyakDyveam.wl 235 + Ya +K + + ++y+++y ++ + n ++ + + v +++ v ++++ ++ +v G ++++R + y kD ++ m w FUN_001658-T1 134 hssNFGYAYSKRMIDVQNKAYHQQYPdgCLFTSVVPTNVYGKHDNFNLedshVLPGLIHKVYLAEKEGKPLVVWGTGSPRRQFIYSKDLARLMiWV 229 111557******************96336666677788777766544311113333333444444444578888*****************85377 PP GDP_Man_Dehyd 236 mlqqdepddyviatge..thsvrefvekafaelgkeiewegkgveevgrakesgkvlv 291 m + +e+d +++ ge + s++e +e+ ++ +g + + e + + g+ k++ ++ FUN_001658-T1 230 MREYNEADPIILSVGEddELSIKEAAELVVEGMGFTGKLEYDTSKSDGQFKKTASNAK 287 88889999999888873367999*******9999998888777777776665544332 PP >> RmlD_sub_bind RmlD substrate binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.0 1.1e-08 5.4e-05 3 60 .. 7 68 .. 5 71 .. 0.85 2 ? -2.2 0.0 0.45 2.3e+03 185 233 .. 218 264 .. 199 290 .. 0.77 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.1e-08 RmlD_sub_bind 3 ilitGanGqlGteLakalaeeg....ievvaltreeldltdaeavaellkeikpdvvvnaAa 60 il+tG++G++G++ ++ +a e+ + l++++ dl dae+ + +++++kp v+++Aa FUN_001658-T1 7 ILVTGGSGLVGQAFQEVVATEEkrpdETWIFLSSKDGDLCDAEETKGIFDKHKPTHVIHLAA 68 9************9998876541111567788999**************************9 PP == domain 2 score: -2.2 bits; conditional E-value: 0.45 RmlD_sub_bind 185 sardlAevllellekkaaeeelsgvyHlanegetswyefAkailkeaga 233 + +dlA+ ++ ++++ ++ ++ ++ ++ ++e+s e A+ +++ +g FUN_001658-T1 218 YSKDLARLMIWVMREYNE--ADPIILSVGEDDELSIKEAAELVVEGMGF 264 568999999999988886..66677777777778888888777776655 PP >> Polysacc_synt_2 Polysaccharide biosynthesis protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.8 0.1 0.0077 40 1 26 [. 7 34 .. 7 42 .. 0.77 2 ! 15.0 0.0 2.9e-06 0.015 60 135 .. 42 123 .. 25 128 .. 0.82 3 ? -0.2 0.0 0.12 6.3e+02 201 251 .. 214 266 .. 196 282 .. 0.69 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0077 Polysacc_synt_2 1 vlvtGagGsiGselvrqilke..kpkki 26 +lvtG++G +G+++ + +++e +p + FUN_001658-T1 7 ILVTGGSGLVGQAFQEVVATEekRPDET 34 89***********999888764455555 PP == domain 2 score: 15.0 bits; conditional E-value: 2.9e-06 Polysacc_synt_2 60 igdvrdkerlekaleelkvdvvfhaAAlKh.vPlveenpleaiktNvlGtenvieaaieagvkkvv.liSt....DKAvnpt 135 gd+ d+e+ + +++++k++ v+h AAl + ++ l++++ N +nv++ ++ ++vkk+v ++St DK +p+ FUN_001658-T1 42 DGDLCDAEETKGIFDKHKPTHVIHLAALVGgLFKNLKYNLDFWRMNTKINDNVLHSCHLSKVKKCVsCLSTcifpDKTTYPI 123 5899***********************96513344468899***********************996688866668888887 PP == domain 3 score: -0.2 bits; conditional E-value: 0.12 Polysacc_synt_2 201 RffmtieeavqLvlqalalakggeifvldmGe..svkivdlakalielsglee 251 R f+ ++ ++L++ + + ++ + ++l +Ge ++i + a+ ++e +g++ FUN_001658-T1 214 RQFIYSKDLARLMIWVMREYNEADPIILSVGEddELSIKEAAELVVEGMGFTG 266 55666666777777777777777777777776224667777777777666654 PP >> NAD_binding_4 Male sterility protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.33 1.7e+03 1 12 [. 9 20 .. 9 39 .. 0.83 2 ? 12.7 0.0 1.4e-05 0.073 90 176 .. 61 161 .. 48 179 .. 0.81 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.33 NAD_binding_4 1 lTGaTGFLGkvL 12 +TG++G +G+++ FUN_001658-T1 9 VTGGSGLVGQAF 20 7********976 PP == domain 2 score: 12.7 bits; conditional E-value: 1.4e-05 NAD_binding_4 90 dviihsAAtvn.fdepyk...ellavNvegtkevlrlakqlkklkafvhvSTayvngeregeveekvyeege..........eeelldelerallk 171 +++ih+AA v + +++k +++++N++ +vl ++ k +k++ ST ++ + + ++e+++++g ++ ++d +++a ++ FUN_001658-T1 61 THVIHLAALVGgLFKNLKynlDFWRMNTKINDNVLHSCHLSKVKKCVSCLSTCIFPDKTTYPIDETMVHNGPphssnfgyaySKRMIDVQNKAYHQ 156 68*******963333443113599****************************88888888899999998777888888888877777777777777 PP NAD_binding_4 172 glpnt 176 ++p++ FUN_001658-T1 157 QYPDG 161 77766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (320 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 791 (0.030965); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3176.87 // Query: FUN_001659-T1 [L=370] Description: FUN_001659 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (370 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 667 (0.0261108); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3729.68 // Query: FUN_001660-T1 [L=776] Description: FUN_001660 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (776 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1930 (0.0755529); expected 510.9 (0.02) Passed bias filter: 553 (0.0216481); expected 510.9 (0.02) Passed Vit filter: 233 (0.00912116); expected 25.5 (0.001) Passed Fwd filter: 77 (0.00301429); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.80u 0.39s 00:00:01.19 Elapsed: 00:00:00.43 # Mc/sec: 7338.94 // Query: FUN_001661-T1 [L=247] Description: FUN_001661 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.5 0.0 0.13 12.9 0.0 1.8 1 RecA_C RecA C-terminal domain Domain annotation for each model (and alignments): >> RecA_C RecA C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 4.9e-06 0.13 4 26 .. 169 191 .. 167 191 .. 0.86 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 4.9e-06 RecA_C 4 lDlavelgiikKsGsWYsYnder 26 + +v+ i+ K+G WY Y + r FUN_001661-T1 169 IVSGVARAIVRKRGVWYVYMNRR 191 557999*************9865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (247 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1862 (0.072891); expected 510.9 (0.02) Passed bias filter: 635 (0.0248581); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2416.34 // Query: FUN_001661-T2 [L=315] Description: FUN_001661 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.061 13.9 0.0 0.17 12.5 0.0 1.7 1 RecA_C RecA C-terminal domain Domain annotation for each model (and alignments): >> RecA_C RecA C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 6.7e-06 0.17 4 26 .. 169 191 .. 167 191 .. 0.86 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 6.7e-06 RecA_C 4 lDlavelgiikKsGsWYsYnder 26 + +v+ i+ K+G WY Y + r FUN_001661-T2 169 IVSGVARAIVRKRGVWYVYMNRR 191 557999*************9865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (315 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1725 (0.0675279); expected 510.9 (0.02) Passed bias filter: 602 (0.0235663); expected 510.9 (0.02) Passed Vit filter: 74 (0.00289685); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 3199.55 // Query: FUN_001662-T1 [L=61] Description: FUN_001662 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (61 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 618 (0.0241926); expected 510.9 (0.02) Passed bias filter: 313 (0.0122529); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 632.09 // Query: FUN_001663-T1 [L=4520] Description: FUN_001663 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (4520 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1713 (0.0670581); expected 510.9 (0.02) Passed bias filter: 486 (0.0190252); expected 510.9 (0.02) Passed Vit filter: 271 (0.0106087); expected 25.5 (0.001) Passed Fwd filter: 95 (0.00371893); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 2.41u 0.46s 00:00:02.87 Elapsed: 00:00:00.60 # Mc/sec: 30459.38 // Query: FUN_001664-T1 [L=546] Description: FUN_001664 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.4e-18 66.4 1.6 1.4e-17 65.1 1.6 1.7 1 Rubis-subs-bind Rubisco LSMT substrate-binding 3.7e-06 27.8 0.0 8.9e-06 26.6 0.0 1.7 1 SET SET domain ------ inclusion threshold ------ 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 Beta-prop_TEP1_2nd TEP-1 second beta-propeller Domain annotation for each model (and alignments): >> Rubis-subs-bind Rubisco LSMT substrate-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.1 1.6 1.6e-21 1.4e-17 2 129 .] 356 489 .. 355 489 .. 0.89 Alignments for each domain: == domain 1 score: 65.1 bits; conditional E-value: 1.6e-21 Rubis-subs-bind 2 psdplyeeKadlLeengl.detqtfplrvdedglpeeLlaylrvlllseedaeelkellsseedke........eaeeplsdenEeaalrllad 86 sd ly++K +lL + ++ +++ ++ + ++++++++L+a+lr++++ ++elke+ls++e+++ ++ e E++++++l++ FUN_001664-T1 356 RSDALYQMKDKLLTSLEMtASSHYYAIPSGDEPISPQLVAFLRIFQM---CEDELKEWLSKAEKAKsetrklfeVQSPSCRHETEARCWKFLET 446 68************99995444555555559****************...9999999999988777889988876667777888********** PP Rubis-subs-bind 87 lckllLaaypttleeDeellkdkelsererlavqlrlgEKrIL 129 +++llLa+y+t ee+ + l+++ s +++l+ +l l E++IL FUN_001664-T1 447 RLSLLLAQYKTPNEEEPKFLNTEGISLHQKLCNKLILAERNIL 489 ******************************************9 PP >> SET SET domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.0 1e-09 8.9e-06 1 105 [] 116 325 .. 116 325 .. 0.81 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 1e-09 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................xxxxxxxxxx................. RF SET 1 GrGlfAtedikkgelileyvekllitkeeadkreee.................................eylftldeke................. 46 G Gl A +dik+gel+ +++kl+++ e+a+ +e + + FUN_001664-T1 116 GLGLKAVTDIKEGELFATIPRKLMMSAETARGSELSpliegdnilkamqnvclvihvyceklkedsfwkP--------Yldilpntysttlyfsle 203 89**************99999888888888888888*************999999955555555555553........055555555888888888 PP .............................................xxxxxxxxxxxxxxxx.....................xxxxxxxxxxxxxx RF SET 47 .............................................aeyvidaraekkgnva.....................rfiNHscepnceve 76 +++++d+++ ++v +++NH c+ ++e FUN_001664-T1 204 elqqlkgspafgealklyrsiarqyaylyqrinqfcpetaklplrNSFTFDGHRWAVSTVItrqnnilsttreptlalipmwDMCNH-CNGTITTE 298 8889999999999999999999999999999999999999999995555554433333333555555577888888899********.98888777 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF SET 77 vevvngekrivvfalrdIkkgeEltidYg 105 ++ e++ + +d k+g++++i Yg FUN_001664-T1 299 YDM--VEDSCKSLSVKDFKAGDQVCIFYG 325 777..69999999***************8 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 1.6e-05 0.13 172 223 .. 252 306 .. 247 326 .. 0.78 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 1.6e-05 Beta-prop_TEP1_2nd 172 kflGhqsavsavvaveehvvsvgrdGllk...vWdlqGveltsikahsgqisqca 223 +f Gh+ avs+v++ +++++s++r+ +l +Wd+ +i+++ + +++++ FUN_001664-T1 252 TFDGHRWAVSTVITRQNNILSTTREPTLAlipMWDMCNHCNGTITTEYDMVEDSC 306 799**********************998633368887777777777776666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (546 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 826 (0.0323351); expected 510.9 (0.02) Passed bias filter: 597 (0.0233705); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 5398.59 // Query: FUN_001665-T1 [L=359] Description: FUN_001665 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-54 185.1 23.1 2.9e-54 184.7 23.1 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 2.4e-13 50.5 20.9 2.9e-13 50.3 20.4 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 7 7.0 20.3 25 5.1 20.0 2.1 1 Git3 G protein-coupled glucose receptor regulating Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 184.7 23.1 3.5e-58 2.9e-54 1 260 [] 38 297 .. 38 297 .. 0.91 Alignments for each domain: == domain 1 score: 184.7 bits; conditional E-value: 3.5e-58 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykri 96 gN+lVilv++ n+++r++tn+++ln+av+Dll++++++p+++ + +++ +++ vlCk++ + ++v++ +s+l+ltai+iDR+laI +plk+ + FUN_001665-T1 38 GNVLVILVVVLNRHMRSVTNYLILNMAVSDLLLTAFNMPVTIKVIV-TRSIDWSVVLCKIIPFTQCVSVASSVLTLTAIAIDRFLAILYPLKR--Y 130 8*****************************************6666.7*********************************************..8 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF 7tm_1 97 rtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe.eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.. 189 +t +a+ +i+vvW++a+++ p l+ +++++++++Cl + ++++++ +t++l+v +++ pl+ ++v+y+++++ l+ ++ + FUN_001665-T1 131 VTFPVAYYMIAVVWIVAIAVNSPVLYAK-KLVFNNNTKKNICLEIWTPiFSENADKDFTVVLFVTFYVFPLSTMSVLYSFVIHNLWVRKVPGIQmp 225 9**********************98866.5567777*******99988566679**********99999*******************99877733 PP .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ +++r+++k+lk+ll+vvv+f+lcwlP+ i+++++ + +++ + + t+ + ++l+++ns++NP Y FUN_001665-T1 226 eNQLRAERSKKKVLKMLLAVVVIFALCWLPVYITQFIAFFGQKKFPCGPPVTLAFVGYFLGHANSAINPAMY 297 34444555566*****************************7777777788888899*************999 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.3 20.4 3.4e-17 2.9e-13 3 255 .. 34 310 .. 31 312 .. 0.73 Alignments for each domain: == domain 1 score: 50.3 bits; conditional E-value: 3.4e-17 7TM_GPCR_Srsx 3 vGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvllltgtqlkreeCFlliiv.yvfgltaqsvllL.vigiDlliavkfPi.r 95 +l+GNvl+il+++ ++++rs +++Li +++dll+ ++++ ++ + ++ + ii+ + +a+svl L +i+iD+++a+ +P+ r FUN_001665-T1 34 ASLVGNVLVILVVVLNRHMRSVTNYLILNMAVSDLLLTAFNMPVTIKVIVTRSIDWSVVLCKIIPfTQCVSVASSVLTLtAIAIDRFLAILYPLkR 129 579****************************************99987766666666555544440334455666666637************956 PP 7TM_GPCR_Srsx 96 YrllskekYllill.ifpvlyssiilvlgflqrdde.tiivCappla..lagkas.....eiftlssliinvivllvylvliiilkkkkek..... 177 Y +++ Y+++++ i+ ++ s +l+ l+ +++ +C + ++++a +f ++ ++ + ++y ++i+ l +k FUN_001665-T1 130 YVTFPVAYYMIAVVwIVAIAVNSPVLYAKKLVFNNNtKKNICLEIWTpiFSENADkdftvVLFVTFYVFPLSTMSVLYSFVIHNLWVRKVPgiqmp 225 999999998877661455677888888888888888578999865543355555521222334444444444566778888887444444455666 PP 7TM_GPCR_Srsx 178 .....kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayag..ilvllsfsqnffVtywrsseYrkafre 255 ++s kkvlk l +vvif ++W+ + i + +++ +++ + + + + +l +++ n + + +s++rk fr+ FUN_001665-T1 226 enqlrAERSKKKVLKMLLAVVVIFALCWLPVYITQFIAFFGQKKFPCGPPVTLAFVgyFLGHANSAINPAMYAIFNSNFRKGFRD 310 66666889999********************999999998888877766555433212555667778888899999999999987 PP >> Git3 G protein-coupled glucose receptor regulating Gpa2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 20.0 0.003 25 8 146 .. 24 164 .. 18 265 .. 0.81 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.003 Git3 8 aivassvsivaglva...lylllaidkrrrvfRhelillLilvdllkalvlliypvvvlvkksvyadkafcqvvGfftavaiegaDiaillfalht 100 +++ s+ ++a+lv+ + l++ ++++ r++ + lil + ++dll + + + +++v+v++s+ + +c+++ f +v++ ++ +++ ++a+ FUN_001665-T1 24 KLISYSIILFASLVGnvlVILVVVLNRHMRSVTNYLILNMAVSDLLLTAFNMPVTIKVIVTRSIDWSVVLCKIIPFTQCVSVASSVLTLTAIAIDR 119 555666666666666332334455678889999*************************************************************** PP Git3 101 allifkpnlrvkksknvegGLykyRklvy..alsvllPlvlas.Lafin 146 +l i+ p k+ ++ y + +v+ a++v P++ a L f n FUN_001665-T1 120 FLAILYP---LKRYVTFPVAYYMIA-VVWivAIAVNSPVLYAKkLVFNN 164 *******...777777777766654.44400444456877774266655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (359 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1110 (0.0434527); expected 510.9 (0.02) Passed bias filter: 383 (0.0149931); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3537.44 // Query: FUN_001668-T1 [L=736] Description: FUN_001668 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-110 370.2 22.4 1.7e-110 369.9 22.4 1.1 1 Sulfate_transp Sulfate permease family 1.4e-13 51.0 0.0 2.9e-13 50.0 0.0 1.5 1 STAS STAS domain ------ inclusion threshold ------ 0.8 9.3 1.8 1.4 8.5 1.8 1.3 1 Bunya_G2 Bunyavirus glycoprotein G2 Domain annotation for each model (and alignments): >> Sulfate_transp Sulfate permease family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 369.9 22.4 2e-114 1.7e-110 1 380 [] 113 520 .. 113 520 .. 0.97 Alignments for each domain: == domain 1 score: 369.9 bits; conditional E-value: 2e-114 Sulfate_transp 1 lkgDliaGitvavlaiPqalaYallaglppiygLyssvvpalvyalfGtsrqlavGpvavlsllvgeiiaklvd..................... 74 l +D+ +G+tv+++ iPq+la+a+la lpp+ gLy++++p lvy+l+Gtsr+l+vG++av++l+v+++++++v+ FUN_001668-T1 113 LVADISGGLTVGIMHIPQGLAFAMLASLPPVTGLYTALIPVLVYMLMGTSRHLSVGSFAVICLMVANVCEREVAkmsfddpstpapgnmsstlsp 207 568**********************************************************************9********************* PP Sulfate_transp 75 ......kd..pekglelaltltllaGiiqlllGllrLgflveflseavlsGfmaGaaivillsqlkvllgle..kvskkeelvsvlsslftnlek 159 ++ + +le+a++l+ l Gi+q+++G +rLg l++f+s++++sGf++G+a+ +++sql +++gl+ +s++ + ++ +++++ FUN_001668-T1 208 ttsssrWSpiDTVKLEIAVSLACLIGIFQIIMGAIRLGVLATFMSDPMISGFTTGSAVLVVISQLPHIFGLKvpPMSSPLTAPKKVIYMLEHIAS 302 99988744568889999*******************************************************99899999999999999999999 PP Sulfate_transp 160 vnlatlvlgllvlvvLlvtkellkklkkllvvpapaelvavvlatlvsalfelkeeagvkivgeipsglpelslpkvswsllsallpdalaialv 254 n ++++g+l+l++L+ +++++++k++l vp+p+el++vv++t +s+ + ++++gv+i+geip+glp++s+p s+s +s+++pda++ia+v FUN_001668-T1 303 SNGGAIITGVLCLLILIGLRQVNDRFKSKLPVPIPGELLVVVIGTAISYGAKINQHFGVSILGEIPKGLPPISVP--SFSWMSKMIPDAFVIAVV 395 9**************************************************************************..9999************** PP Sulfate_transp 255 alleaiavsksfakkkgyevdsnkELvAlGfaNilsslfgglpatgalsrsavnikaGaktqlsglvsavvvllvllvltplleyiPkavLaaii 349 ++ i+vsk+fakk+gy++d+n+EL+A G++N+++s+ +++++ al+r+av+++ a+tql ++v +v++llvll+l+pl++y+Pka+La+++ FUN_001668-T1 396 IFATNISVSKMFAKKRGYTIDPNQELIAYGVGNVAGSFSSCFAICNALARTAVQENL-ANTQLCSIVVIVLILLVLLFLAPLFFYLPKAILASVV 489 *****************************************************9886.9************************************ PP Sulfate_transp 350 ivallglLvelkelkklwklskldflillat 380 i +l+glL+++ lk lw + + d++++++t FUN_001668-T1 490 IANLIGLLKQFTRLKALWYIYRPDAVVWFLT 520 ****************************976 PP >> STAS STAS domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.0 0.0 3.4e-17 2.9e-13 6 92 .. 576 710 .. 573 728 .. 0.93 Alignments for each domain: == domain 1 score: 50.0 bits; conditional E-value: 3.4e-17 STAS 6 etdgililrlsgpldfanaeslrerllraleeee................................................ikkvvldlsavsfi 53 e +gi ++r+++ l+f+n+e++r++l ++ ++ ++++v+d s +fi FUN_001668-T1 576 EVPGIKVMRFESSLYFGNVERFRKALVAITGHDPtikeekksseaksnngelvesnktgkgrqvkgsnheatavsvddpdevVRVIVIDGSSFTFI 671 679*****************************99************************************************************** PP STAS 54 DssglgvLeelykelkrrgvelvLvgispevartlektg 92 Ds+gl++L ++k++k+ gv+++L+g+s+ ++ +l +++ FUN_001668-T1 672 DSMGLQTLPAVIKDYKKFGVQIYLAGCSSYIKTRLVNSK 710 ********************************9988765 PP >> Bunya_G2 Bunyavirus glycoprotein G2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 1.8 0.00017 1.4 121 224 .. 402 502 .. 394 508 .. 0.81 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00017 Bunya_G2 121 iksgwfknkasveleqtcehikvtCGkkslqlhacfkqhmsCirflkksilpelma.esiCqnielilllvliliifiililltktyivylllpif 215 s++f +k ++++ e i G+ + ++ +cf C l+++ + e++a +++C+ + ++l+l+++l++ +++ l k ++ +++ + FUN_001668-T1 402 SVSKMFAKKRGYTIDPNQELIAYGVGNVAGSFSSCFA---ICN-ALARTAVQENLAnTQLCSIVVIVLILLVLLFLAPLFFYLPKAILASVVIANL 493 4578999999**************************6...684.555555655555168****999999999999999999999999999999888 PP Bunya_G2 216 ipiaylygk 224 i + + ++ FUN_001668-T1 494 IGLLKQFTR 502 777776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (736 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1163 (0.0455275); expected 510.9 (0.02) Passed bias filter: 626 (0.0245058); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.39u 0.41s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7097.64 // Query: FUN_001669-T1 [L=78] Description: FUN_001669 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (78 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 351 (0.0137405); expected 510.9 (0.02) Passed bias filter: 311 (0.0121746); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 795.16 // Query: FUN_001670-T1 [L=104] Description: FUN_001670 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0014 18.7 0.1 0.0019 18.3 0.1 1.2 1 SAP SAP domain ------ inclusion threshold ------ 0.2 12.0 0.0 0.27 11.6 0.0 1.3 1 Ulvan_lyaseC Endo-acting ulvan lyase C-terminal domain Domain annotation for each model (and alignments): >> SAP SAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.1 1.5e-07 0.0019 3 37 .] 30 66 .. 28 66 .. 0.95 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 1.5e-07 SAP 3 skltvseLKeeLkkrGLptsGk..KaeLieRLkeyle 37 s+l+ eL+ L+ rG + +G Ka L++R++ey++ FUN_001670-T1 30 SSLKNEELRFWLRCRGDSLKGLntKALLVKRVEEYVK 66 89*********************************75 PP >> Ulvan_lyaseC Endo-acting ulvan lyase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 2.1e-05 0.27 20 55 .. 63 96 .. 47 104 .] 0.78 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.1e-05 Ulvan_lyaseC 20 skveskeltqyiisdskdeeykkkeldisFkGtFav 55 ++ + q++i + de y +k+++isF Gt + FUN_001670-T1 63 EY-VKSGRDQMVIDPDPDEIY-TKTKKISFAGTLCM 96 33.456899*****9999999.8999******9865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 511 (0.0200039); expected 510.9 (0.02) Passed bias filter: 480 (0.0187904); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.34s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1058.94 // Query: FUN_001671-T1 [L=2188] Description: FUN_001671 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-12 45.3 10.8 0.11 13.7 0.0 8.2 8 TPR_14 Tetratricopeptide repeat 2.5e-10 41.2 7.2 0.018 15.6 0.3 4.9 4 HAT_PRP39_N PRP39 N-terminal HAT repeat 9.7e-10 39.1 3.0 0.016 16.0 0.8 5.9 5 TPR_19 Tetratricopeptide repeat 3.9e-07 30.5 7.9 0.00027 21.2 0.1 5.0 5 HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-ter 1.9e-06 28.0 6.0 7.7e-06 26.1 6.0 2.1 1 zf-C3H1 Putative zinc-finger domain 6.2e-06 25.5 6.8 0.15 11.0 0.0 4.7 5 Suf Suppressor of forked protein (Suf) 0.00043 20.8 0.2 0.95 10.4 0.1 4.0 4 TPR_17 Tetratricopeptide repeat 0.0013 19.6 1.5 1.4 9.9 3.1 3.7 3 TPR_16 Tetratricopeptide repeat ------ inclusion threshold ------ 0.099 12.8 1.9 0.25 11.5 1.9 1.7 1 zf-CCCH_12 CCCH zinc finger domain 0.15 12.8 0.2 0.57 10.9 0.0 2.1 2 DUF7648 Domain of unknown function (DUF7648) 1 10.2 3.6 3.3 8.6 0.3 3.5 3 TPR_8 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.014 33 21 44 .] 1519 1542 .. 1517 1542 .. 0.93 2 ? 6.5 0.1 0.01 24 15 44 .] 1558 1587 .. 1556 1587 .. 0.91 3 ! 9.5 0.1 0.0011 2.6 2 41 .. 1579 1618 .. 1578 1619 .. 0.93 4 ? 5.0 0.0 0.032 74 2 29 .. 1655 1682 .. 1654 1689 .. 0.90 5 ! 13.7 0.0 4.8e-05 0.11 3 44 .] 1785 1826 .. 1783 1826 .. 0.93 6 ! 10.4 0.9 0.00057 1.3 2 43 .. 1818 1859 .. 1817 1860 .. 0.89 7 ? 4.7 0.4 0.04 92 5 29 .. 1855 1879 .. 1851 1882 .. 0.90 8 ? -0.1 0.0 1.5 3.4e+03 8 35 .. 2117 2144 .. 2111 2150 .. 0.72 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.014 TPR_14 21 lelleralaldPddpeawlalarl 44 +e le+ l P+d ++w++la+l FUN_001671-T1 1519 IETLEASLDNSPGDVALWIKLAKL 1542 6889******************96 PP == domain 2 score: 6.5 bits; conditional E-value: 0.01 TPR_14 15 GdpdeAlelleralaldPddpeawlalarl 44 ++ ++Al l r+l+ + +++++wl++ +l FUN_001671-T1 1558 DNVSQALSTLSRGLEENANSEALWLEYLEL 1587 67899********************99875 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0011 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlal 41 ++wl +++++ + + de +e+ ++a++ P++ +w+ l FUN_001671-T1 1579 ALWLEYLELYSSRCNQDELREICDQAVEFSPTYSVWWKYL 1618 79******************************99998765 PP == domain 4 score: 5.0 bits; conditional E-value: 0.032 TPR_14 2 eawlalarallalGdpdeAlellerala 29 e++l+ ++++l G+++ Al ++++al FUN_001671-T1 1655 EILLYFVQLELYSGHFKSALSVFKAALG 1682 789999********************85 PP == domain 5 score: 13.7 bits; conditional E-value: 4.8e-05 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlalarl 44 +++ l+++++a G+ d A+ + +l+ +P+ +wl la l FUN_001671-T1 1785 LYKNLIALEMAYGRIDSARGICHHLLKDNPSVVVLWLCLAAL 1826 6778999********************************976 PP == domain 6 score: 10.4 bits; conditional E-value: 0.00057 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlalar 43 +wl la+++ ++ ++A++++e+al+++ +++ + + +ar FUN_001671-T1 1818 VLWLCLAALEDDRQGGADARQVYEKALEKCRGHAMVAYSAAR 1859 68****************************999888776665 PP == domain 7 score: 4.7 bits; conditional E-value: 0.04 TPR_14 5 lalarallalGdpdeAlellerala 29 + +ar++l+ ++ ++Al++l+++++ FUN_001671-T1 1855 YSAARFYLEKNEVEAALAVLRKCVQ 1879 6789******************975 PP == domain 8 score: -0.1 bits; conditional E-value: 1.5 TPR_14 8 arallalGdpdeAlelleralaldPddp 35 ++++l+++ +eA++++++a + P + FUN_001671-T1 2117 IAIELQRNCVHEARKMYQQATEILPFAA 2144 555566666789********99888655 PP >> HAT_PRP39_N PRP39 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.3 7.9e-06 0.018 7 98 .. 1526 1627 .. 1516 1693 .. 0.55 2 ! 8.7 0.0 0.001 2.4 19 81 .. 1788 1850 .. 1778 1920 .. 0.79 3 ! 6.4 0.1 0.0051 12 84 138 .. 1945 1999 .. 1938 2046 .. 0.71 4 ! 10.6 0.0 0.00027 0.63 28 97 .. 2090 2159 .. 2080 2178 .. 0.81 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.9e-06 HAT_PRP39_N 7 vkenpedfnaWtkL..lqyveq.........endiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYl 89 ++++p d+ W+kL lq + +++++a ++ ++ L+e + w Y +l + +n+++ +e+++++v+ p +W +Yl FUN_001671-T1 1526 LDNSPGDVALWIKLakLQLHQAsdgdnvdtcLDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSP-TYSVWWKYL 1618 555666666666663333333333333322225555555666666666777777777777777777777777777777777665.345677777 PP HAT_PRP39_N 90 eflketlek 98 e+ k+ ++k FUN_001671-T1 1619 EYSKTYFAK 1627 777766543 PP == domain 2 score: 8.7 bits; conditional E-value: 0.001 HAT_PRP39_N 19 kLlqyveqendiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaipls 81 +L++ +i++ar + +++L+ P ++ w a le + ++a++vye+++++++ + FUN_001671-T1 1788 NLIALEMAYGRIDSARGICHHLLKDNPSVVVLWLCLAALEDDRQGGADARQVYEKALEKCRGH 1850 566665566788999999999999999999999999999999999999999999999887654 PP == domain 3 score: 6.4 bits; conditional E-value: 0.0051 HAT_PRP39_N 84 lWlhYleflketlekedpeseekirelferavaavGldfrsdklWdkYiefekeq 138 lWl+Y+ +l + + ++ + +++fe+av++ + ++lW++Y+ +++++ FUN_001671-T1 1945 LWLSYCLLLEISPPCPTVWDNVSAESAFETAVHSPLDRQDVQTLWTEYLLYQRSK 1999 7888888777655555556667778888888888888888888888888776543 PP == domain 4 score: 10.6 bits; conditional E-value: 0.00027 HAT_PRP39_N 28 ndiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYleflketle 97 ++ + +++ +FL+ P ++ wk +e + + +++a+++y+++ + +p l ++l f ++ FUN_001671-T1 2090 KSFDLSKKICASFLSDNPFSISMWKVAIAIELQRNCVHEARKMYQQATEILPFAATLRKDFLMFELAQKG 2159 45677788999********************************************999999999876533 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.01 24 11 38 .. 1519 1546 .. 1517 1548 .. 0.92 2 ! 6.1 0.0 0.0087 20 8 57 .. 1561 1610 .. 1558 1617 .. 0.83 3 ? 1.0 0.0 0.34 7.9e+02 26 60 .. 1655 1690 .. 1649 1698 .. 0.65 4 ? 3.5 0.0 0.054 1.2e+02 27 56 .. 1785 1814 .. 1760 1824 .. 0.80 5 ! 16.0 0.8 6.8e-06 0.016 8 49 .. 1834 1875 .. 1833 1880 .. 0.96 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.01 TPR_19 11 lalLeqalaedPdnaearllLArallal 38 ++ Le+ l+ +P++ ++++ LA+++l++ FUN_001671-T1 1519 IETLEASLDNSPGDVALWIKLAKLQLHQ 1546 57899********************987 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0087 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpd 57 +Al+ L + l+e+ ++ +++l + +++ + de +++ +++ + p FUN_001671-T1 1561 SQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSPT 1610 689999********************999999988888888888776665 PP == domain 3 score: 1.0 bits; conditional E-value: 0.34 TPR_19 26 earllLArallalgrldeAealLaalpaadpdd.pe 60 e++l +++ l +g+++ A +++a++ ++ +d +e FUN_001671-T1 1655 EILLYFVQLELYSGHFKSALSVFKAALGKKVQDqSE 1690 566666666666677777777766666666666555 PP == domain 4 score: 3.5 bits; conditional E-value: 0.054 TPR_19 27 arllLArallalgrldeAealLaalpaadp 56 ++ +L+ + +a gr+d A+ + l++++p FUN_001671-T1 1785 LYKNLIALEMAYGRIDSARGICHHLLKDNP 1814 455889999*************99999998 PP == domain 5 score: 16.0 bits; conditional E-value: 6.8e-06 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLa 49 ++A++++e+al++ ++a +++ Ar++l+ +++++A a+L FUN_001671-T1 1834 ADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLR 1875 69*************************************996 PP >> HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.2 1.4 3.3e+03 41 84 .. 836 879 .. 818 881 .. 0.82 2 ! 21.2 0.1 1.2e-07 0.00027 38 144 .. 1521 1625 .. 1509 1637 .. 0.86 3 ? 0.1 0.0 0.38 8.9e+02 12 50 .. 1813 1851 .. 1807 1882 .. 0.61 4 ? 4.6 0.1 0.016 37 50 91 .. 1986 2026 .. 1937 2046 .. 0.78 5 ? 4.1 0.0 0.022 52 11 63 .. 2105 2157 .. 2101 2174 .. 0.86 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.4 HAT_Syf1_CNRKL1_N 41 RAlkelprsyklWkaYlklrvkqvkkknpvkkeeeyekvnnlfe 84 A++++p+ +k ++ lk+r ++ +k+++ +k ++++++++++e FUN_001671-T1 836 DAMDHMPEQMKNEYRRLKERLAHREKTKQQDKGDRMKSTSEVHE 879 58999999999999999***999999999998899999888887 PP == domain 2 score: 21.2 bits; conditional E-value: 1.2e-07 HAT_Syf1_CNRKL1_N 38 vyeRAlkelprsyklWkaYlklrvkqvkkk.npvkkeeeyekvnnlferalvllnkmpriWldYlefllkqkkvtktrrtfdraLralpi 126 +e +l++ p+ + lW + kl+ +q+++ n+ + ++++++ ++ r l + +Wl+Yle+ ++++ + r+++d+a++ p FUN_001671-T1 1521 TLEASLDNSPGDVALWIKLAKLQLHQASDGdNVDTCLDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSP- 1609 56888999***************9999876155556789999999*****************************************999. PP HAT_Syf1_CNRKL1_N 127 tqheriWelylkfaksae 144 +W yl++ k+ FUN_001671-T1 1610 --TYSVWWKYLEYSKTYF 1625 ..678*******998754 PP == domain 3 score: 0.1 bits; conditional E-value: 0.38 HAT_Syf1_CNRKL1_N 12 npysvkaWlrYiehkkkkksleelalvyeRAlkelprsy 50 np v Wl + ++ +++ + vye+Al++ ++ FUN_001671-T1 1813 NPSVVVLWLCLAALEDDRQGGADARQVYEKALEKCRGHA 1851 555666677777776666666667777777777666554 PP == domain 4 score: 4.6 bits; conditional E-value: 0.016 HAT_Syf1_CNRKL1_N 50 yklWkaYlklrvkqvkkknpvkkeeeyekvnnlferalvlln 91 lW++Yl ++++ +++ + +++ +++++l +r+l+ ++ FUN_001671-T1 1986 QTLWTEYLLYQRSKFMQREK-SFTPHQQHMSELVNRCLMSVS 2026 579*****999999988875.57899999999999*999876 PP == domain 5 score: 4.1 bits; conditional E-value: 0.022 HAT_Syf1_CNRKL1_N 11 rnpysvkaWlrYiehkkkkksleelalvyeRAlkelprsyklWkaYlklrvkq 63 np+s+++W i ++ +++ ++e +y+ A + lp l k++l + +q FUN_001671-T1 2105 DNPFSISMWKVAIAIELQRNCVHEARKMYQQATEILPFAATLRKDFLMFELAQ 2157 699***************999************************99987665 PP >> zf-C3H1 Putative zinc-finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 6.0 3.3e-09 7.7e-06 1 21 [. 1351 1370 .. 1351 1370 .. 0.97 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 3.3e-09 zf-C3H1 1 LCpyElaGGvCNDesCefQHF 21 LC ++l G +CNDe+C+fQH+ FUN_001671-T1 1351 LCNFDLQG-KCNDEDCKFQHL 1370 8*******.***********6 PP >> Suf Suppressor of forked protein (Suf) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.3 0.001 2.3 4 95 .. 1520 1622 .. 1517 1629 .. 0.66 2 ! 5.2 0.0 0.0038 8.7 283 354 .. 1820 1891 .. 1790 1954 .. 0.73 3 ? 1.4 0.1 0.055 1.3e+02 85 135 .. 1987 2042 .. 1964 2071 .. 0.71 4 ! 5.1 0.0 0.0039 9.2 39 89 .. 2064 2115 .. 2059 2118 .. 0.91 5 ! 11.0 0.0 6.5e-05 0.15 10 76 .. 2103 2170 .. 2095 2178 .. 0.88 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.001 Suf 4 gkledrieenpldieawleLik..eaqsk.........dkieevrevyekllkqFplaarlWkayieaelkrkefeeveklfsrcLlkvldveL 86 ++le++++++p d+ w +L k +q++ d+++++ ++ ++ l++ ++ +lW +y+e +r + +e ++ ++ ++ FUN_001671-T1 1520 ETLEASLDNSPGDVALWIKLAKlqLHQASdgdnvdtclDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSPTYSV 1613 6677777777777777777744112333233333333345666666777777777777888888888888888888888888888888888888 PP Suf 87 WklYldYvr 95 W Yl+Y + FUN_001671-T1 1614 WWKYLEYSK 1622 888888855 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0038 Suf 283 WyeaaeyleesskeeeaaklleraikalpesllLtfklaeleEsrnkiekvkeiyeklldallkelkklkee 354 W+ a ++ + +a +++e+a++ ++ ++++++ a ++ ++n++e++ ++ +k++++ +++++ ++e FUN_001671-T1 1820 WLCLAALEDDRQGGADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLRKCVQYKFASVSQSSKE 1891 555555555555557788888888888888888888888888888888888888888885555554444443 PP == domain 3 score: 1.4 bits; conditional E-value: 0.055 Suf 85 eLWklYldYvr.....rkndlitggeearetvikAyefalekigldieSgsiwadY 135 LW+ Yl Y r r++ ++ +++++ e v + + ++ + +S+ +w+dY FUN_001671-T1 1987 TLWTEYLLYQRskfmqREKSFTPHQQHMSELVNRCLMSVSTSSSFPFSSSAVWQDY 2042 59999998866111114455556666666777777777777777999999999999 PP == domain 4 score: 5.1 bits; conditional E-value: 0.0039 Suf 39 vyekllkqFplaarlWkayieaelkrkefeeveklfsrcLlkvl.dveLWkl 89 ++k+ k+Fp +a+l + ++e+++k f+ +k+ + L+++ ++++Wk+ FUN_001671-T1 2064 EFQKFRKIFPGSASLAMWSCKHEMEKKSFDLSKKICASFLSDNPfSISMWKV 2115 699**************************************96549****97 PP == domain 5 score: 11.0 bits; conditional E-value: 6.5e-05 Suf 10 ieenpldieawleLikeaqskdkieevrevyekllkqFplaarlWkayieaelkrk.efeeveklfsr 76 +++np+ i+ w i +++ ++e+r++y++ +++ p+aa+l k + el++k + ++v++++++ FUN_001671-T1 2103 LSDNPFSISMWKVAIAIELQRNCVHEARKMYQQATEILPFAATLRKDFLMFELAQKgDGAAVQEIMAK 2170 6789*************************************************987245668888776 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.02 46 2 26 .. 1522 1546 .. 1521 1555 .. 0.90 2 ? -2.8 0.0 7 1.6e+04 2 13 .. 1601 1612 .. 1600 1614 .. 0.89 3 ? -1.1 0.0 2 4.7e+03 5 22 .. 1809 1826 .. 1808 1832 .. 0.86 4 ! 10.4 0.1 0.00041 0.95 2 33 .. 1840 1871 .. 1839 1872 .. 0.95 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.02 TPR_17 2 ylkaleldPnnadayynLArlllnn 26 ++ +l++ P ++ ++ LA l+l++ FUN_001671-T1 1522 LEASLDNSPGDVALWIKLAKLQLHQ 1546 5789*****************9976 PP == domain 2 score: -2.8 bits; conditional E-value: 7 TPR_17 2 ylkaleldPnna 13 +++a+e P+++ FUN_001671-T1 1601 CDQAVEFSPTYS 1612 89********87 PP == domain 3 score: -1.1 bits; conditional E-value: 2 TPR_17 5 aleldPnnadayynLArl 22 l+ +P + ++ +LA l FUN_001671-T1 1809 LLKDNPSVVVLWLCLAAL 1826 68899999*******986 PP == domain 4 score: 10.4 bits; conditional E-value: 0.00041 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 y+kale++ +a + y Ar++l++++ e Al FUN_001671-T1 1840 YEKALEKCRGHAMVAYSAARFYLEKNEVEAAL 1871 9***************************9997 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.61 1.4e+03 17 44 .. 1519 1546 .. 1517 1555 .. 0.90 2 ? 2.2 0.0 0.16 3.7e+02 5 26 .. 1662 1683 .. 1660 1691 .. 0.87 3 ! 9.9 3.1 0.00061 1.4 13 56 .. 1833 1876 .. 1823 1882 .. 0.91 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.61 TPR_16 17 aaaleaalrrnPeaaaAllglGlallrq 44 ++ lea l++ P ++a + l+ + l+q FUN_001671-T1 1519 IETLEASLDNSPGDVALWIKLAKLQLHQ 1546 68899*******************9997 PP == domain 2 score: 2.2 bits; conditional E-value: 0.16 TPR_16 5 raalaagdyddAaaaleaalrr 26 +++l++g++ A+ ++aal + FUN_001671-T1 1662 QLELYSGHFKSALSVFKAALGK 1683 6889***************976 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00061 TPR_16 13 yddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayra 56 +dA+ +e al++ +a ++ ++ +l+++++++A+a++r+ FUN_001671-T1 1833 GADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLRK 1876 589************99***********************9986 PP >> zf-CCCH_12 CCCH zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 1.9 0.00011 0.25 14 27 .. 1356 1369 .. 1351 1371 .. 0.90 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00011 zf-CCCH_12 14 LrGsCengdCeYdH 27 L+G+C+++dC+++H FUN_001671-T1 1356 LQGKCNDEDCKFQH 1369 9************* PP >> DUF7648 Domain of unknown function (DUF7648) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 9.1 2.1e+04 31 57 .. 902 928 .. 891 929 .. 0.73 2 ? 10.9 0.0 0.00025 0.57 13 42 .. 1417 1446 .. 1411 1451 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 9.1 DUF7648 31 dlrKpngeryayssylhAvldcLRnrs 57 +l +++ ++ +s+l+ +l LR+++ FUN_001671-T1 902 NLANHKKLIQQDKSFLDKILSELRDKN 928 556666666677899999999999987 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00025 DUF7648 13 nknitYeelCdavlqhwkdlrKpngeryay 42 +++++YeelC + + k+ rK+ng y + FUN_001671-T1 1417 GEKMSYEELCILIVNEIKKQRKANGPYYVH 1446 679*********************988876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 2.3 5.4e+03 20 29 .. 1836 1845 .. 1834 1845 .. 0.89 2 ? 8.6 0.3 0.0014 3.3 5 31 .. 1855 1881 .. 1853 1883 .. 0.90 3 ? -0.7 0.0 1.4 3.2e+03 18 30 .. 2127 2139 .. 2126 2141 .. 0.90 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.3 TPR_8 20 Akeyyekale 29 A+++yekale FUN_001671-T1 1836 ARQVYEKALE 1845 899*****97 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0014 TPR_8 5 ynlGliylklgdyeeAkeyyekaleld 31 y ++ yl++++ e+A ++++k+++++ FUN_001671-T1 1855 YSAARFYLEKNEVEAALAVLRKCVQYK 1881 77899******************9875 PP == domain 3 score: -0.7 bits; conditional E-value: 1.4 TPR_8 18 eeAkeyyekalel 30 +eA++ y++a+e+ FUN_001671-T1 2127 HEARKMYQQATEI 2139 59********997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2224 (0.087062); expected 510.9 (0.02) Passed bias filter: 519 (0.0203171); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.72u 0.44s 00:00:01.15 Elapsed: 00:00:00.43 # Mc/sec: 20521.58 // Query: FUN_001671-T2 [L=2188] Description: FUN_001671 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-12 47.2 10.6 0.11 13.7 0.0 8.4 8 TPR_14 Tetratricopeptide repeat 1.7e-12 48.2 8.0 0.0026 18.3 0.1 4.9 4 HAT_PRP39_N PRP39 N-terminal HAT repeat 9.9e-10 39.1 3.0 0.016 16.0 0.8 5.9 5 TPR_19 Tetratricopeptide repeat 3.6e-09 37.1 8.7 0.00027 21.2 0.1 5.0 5 HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-ter 6.7e-08 32.0 7.6 0.00086 18.4 0.0 4.7 5 Suf Suppressor of forked protein (Suf) 1.9e-06 28.0 6.0 7.7e-06 26.1 6.0 2.1 1 zf-C3H1 Putative zinc-finger domain 0.00041 20.9 0.2 0.95 10.4 0.1 4.1 4 TPR_17 Tetratricopeptide repeat 0.0028 18.6 2.7 1.4 9.9 3.1 3.8 4 TPR_16 Tetratricopeptide repeat ------ inclusion threshold ------ 0.1 12.8 1.9 0.25 11.5 1.9 1.7 1 zf-CCCH_12 CCCH zinc finger domain 0.15 12.8 0.2 0.57 10.9 0.0 2.1 2 DUF7648 Domain of unknown function (DUF7648) 1 10.2 3.6 3.3 8.6 0.3 3.5 3 TPR_8 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.014 33 21 44 .] 1519 1542 .. 1517 1542 .. 0.93 2 ? 6.5 0.1 0.01 24 15 44 .] 1558 1587 .. 1556 1587 .. 0.91 3 ! 9.5 0.1 0.0011 2.6 2 41 .. 1579 1618 .. 1578 1619 .. 0.93 4 ? 5.0 0.0 0.032 74 2 29 .. 1655 1682 .. 1654 1689 .. 0.90 5 ! 13.7 0.0 4.8e-05 0.11 3 44 .] 1785 1826 .. 1783 1826 .. 0.93 6 ! 10.4 0.9 0.00057 1.3 2 43 .. 1818 1859 .. 1817 1860 .. 0.89 7 ? 4.7 0.4 0.04 92 5 29 .. 1855 1879 .. 1851 1882 .. 0.90 8 ? 2.1 0.0 0.28 6.5e+02 8 39 .. 2117 2148 .. 2111 2153 .. 0.79 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.014 TPR_14 21 lelleralaldPddpeawlalarl 44 +e le+ l P+d ++w++la+l FUN_001671-T2 1519 IETLEASLDNSPGDVALWIKLAKL 1542 6889******************96 PP == domain 2 score: 6.5 bits; conditional E-value: 0.01 TPR_14 15 GdpdeAlelleralaldPddpeawlalarl 44 ++ ++Al l r+l+ + +++++wl++ +l FUN_001671-T2 1558 DNVSQALSTLSRGLEENANSEALWLEYLEL 1587 67899********************99875 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0011 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlal 41 ++wl +++++ + + de +e+ ++a++ P++ +w+ l FUN_001671-T2 1579 ALWLEYLELYSSRCNQDELREICDQAVEFSPTYSVWWKYL 1618 79******************************99998765 PP == domain 4 score: 5.0 bits; conditional E-value: 0.032 TPR_14 2 eawlalarallalGdpdeAlellerala 29 e++l+ ++++l G+++ Al ++++al FUN_001671-T2 1655 EILLYFVQLELYSGHFKSALSVFKAALG 1682 789999********************85 PP == domain 5 score: 13.7 bits; conditional E-value: 4.8e-05 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlalarl 44 +++ l+++++a G+ d A+ + +l+ +P+ +wl la l FUN_001671-T2 1785 LYKNLIALEMAYGRIDSARGICHHLLKDNPSVVVLWLCLAAL 1826 6778999********************************976 PP == domain 6 score: 10.4 bits; conditional E-value: 0.00057 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlalar 43 +wl la+++ ++ ++A++++e+al+++ +++ + + +ar FUN_001671-T2 1818 VLWLCLAALEDDRQGGADARQVYEKALEKCRGHAMVAYSAAR 1859 68****************************999888776665 PP == domain 7 score: 4.7 bits; conditional E-value: 0.04 TPR_14 5 lalarallalGdpdeAlellerala 29 + +ar++l+ ++ ++Al++l+++++ FUN_001671-T2 1855 YSAARFYLEKNEVEAALAVLRKCVQ 1879 6789******************975 PP == domain 8 score: 2.1 bits; conditional E-value: 0.28 TPR_14 8 arallalGdpdeAlelleralaldPddpeawl 39 ++++l+++ +eA++++++a + P + +w+ FUN_001671-T2 2117 IAIELQRNCVHEARKMYQQATEILPFAATLWK 2148 555666666789*************9999996 PP >> HAT_PRP39_N PRP39 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.3 7.9e-06 0.018 7 98 .. 1526 1627 .. 1516 1693 .. 0.55 2 ! 8.7 0.0 0.001 2.4 19 81 .. 1788 1850 .. 1778 1920 .. 0.79 3 ! 6.4 0.1 0.0051 12 84 138 .. 1945 1999 .. 1938 2046 .. 0.71 4 ! 18.3 0.1 1.1e-06 0.0026 28 98 .. 2090 2160 .. 2080 2178 .. 0.82 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.9e-06 HAT_PRP39_N 7 vkenpedfnaWtkL..lqyveq.........endiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYl 89 ++++p d+ W+kL lq + +++++a ++ ++ L+e + w Y +l + +n+++ +e+++++v+ p +W +Yl FUN_001671-T2 1526 LDNSPGDVALWIKLakLQLHQAsdgdnvdtcLDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSP-TYSVWWKYL 1618 555666666666663333333333333322225555555666666666777777777777777777777777777777777665.345677777 PP HAT_PRP39_N 90 eflketlek 98 e+ k+ ++k FUN_001671-T2 1619 EYSKTYFAK 1627 777766543 PP == domain 2 score: 8.7 bits; conditional E-value: 0.001 HAT_PRP39_N 19 kLlqyveqendiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaipls 81 +L++ +i++ar + +++L+ P ++ w a le + ++a++vye+++++++ + FUN_001671-T2 1788 NLIALEMAYGRIDSARGICHHLLKDNPSVVVLWLCLAALEDDRQGGADARQVYEKALEKCRGH 1850 566665566788999999999999999999999999999999999999999999999887654 PP == domain 3 score: 6.4 bits; conditional E-value: 0.0051 HAT_PRP39_N 84 lWlhYleflketlekedpeseekirelferavaavGldfrsdklWdkYiefekeq 138 lWl+Y+ +l + + ++ + +++fe+av++ + ++lW++Y+ +++++ FUN_001671-T2 1945 LWLSYCLLLEISPPCPTVWDNVSAESAFETAVHSPLDRQDVQTLWTEYLLYQRSK 1999 7888888777655555556667778888888888888888888888888776543 PP == domain 4 score: 18.3 bits; conditional E-value: 1.1e-06 HAT_PRP39_N 28 ndiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYleflketlek 98 ++ + +++ +FL+ P ++ wk +e + + +++a+++y+++ + +p lW ++l f ++ + FUN_001671-T2 2090 KSFDLSKKICASFLSDNPFSISMWKVAIAIELQRNCVHEARKMYQQATEILPFAATLWKDFLMFELAQKGD 2160 45677788999****************************************************98875432 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.01 24 11 38 .. 1519 1546 .. 1517 1548 .. 0.92 2 ! 6.1 0.0 0.0087 20 8 57 .. 1561 1610 .. 1558 1617 .. 0.83 3 ? 1.0 0.0 0.34 7.9e+02 26 60 .. 1655 1690 .. 1649 1698 .. 0.65 4 ? 3.5 0.0 0.054 1.2e+02 27 56 .. 1785 1814 .. 1760 1824 .. 0.80 5 ! 16.0 0.8 6.8e-06 0.016 8 49 .. 1834 1875 .. 1833 1880 .. 0.96 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.01 TPR_19 11 lalLeqalaedPdnaearllLArallal 38 ++ Le+ l+ +P++ ++++ LA+++l++ FUN_001671-T2 1519 IETLEASLDNSPGDVALWIKLAKLQLHQ 1546 57899********************987 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0087 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpd 57 +Al+ L + l+e+ ++ +++l + +++ + de +++ +++ + p FUN_001671-T2 1561 SQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSPT 1610 689999********************999999988888888888776665 PP == domain 3 score: 1.0 bits; conditional E-value: 0.34 TPR_19 26 earllLArallalgrldeAealLaalpaadpdd.pe 60 e++l +++ l +g+++ A +++a++ ++ +d +e FUN_001671-T2 1655 EILLYFVQLELYSGHFKSALSVFKAALGKKVQDqSE 1690 566666666666677777777766666666666555 PP == domain 4 score: 3.5 bits; conditional E-value: 0.054 TPR_19 27 arllLArallalgrldeAealLaalpaadp 56 ++ +L+ + +a gr+d A+ + l++++p FUN_001671-T2 1785 LYKNLIALEMAYGRIDSARGICHHLLKDNP 1814 455889999*************99999998 PP == domain 5 score: 16.0 bits; conditional E-value: 6.8e-06 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLa 49 ++A++++e+al++ ++a +++ Ar++l+ +++++A a+L FUN_001671-T2 1834 ADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLR 1875 69*************************************996 PP >> HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.2 1.4 3.3e+03 41 84 .. 836 879 .. 818 881 .. 0.82 2 ! 21.2 0.1 1.2e-07 0.00027 38 144 .. 1521 1625 .. 1509 1637 .. 0.86 3 ? 0.1 0.0 0.38 8.9e+02 12 50 .. 1813 1851 .. 1807 1882 .. 0.61 4 ? 4.6 0.1 0.016 37 50 91 .. 1986 2026 .. 1937 2046 .. 0.78 5 ! 11.5 0.0 0.00011 0.26 11 63 .. 2105 2157 .. 2101 2174 .. 0.87 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.4 HAT_Syf1_CNRKL1_N 41 RAlkelprsyklWkaYlklrvkqvkkknpvkkeeeyekvnnlfe 84 A++++p+ +k ++ lk+r ++ +k+++ +k ++++++++++e FUN_001671-T2 836 DAMDHMPEQMKNEYRRLKERLAHREKTKQQDKGDRMKSTSEVHE 879 58999999999999999***999999999998899999888887 PP == domain 2 score: 21.2 bits; conditional E-value: 1.2e-07 HAT_Syf1_CNRKL1_N 38 vyeRAlkelprsyklWkaYlklrvkqvkkk.npvkkeeeyekvnnlferalvllnkmpriWldYlefllkqkkvtktrrtfdraLralpi 126 +e +l++ p+ + lW + kl+ +q+++ n+ + ++++++ ++ r l + +Wl+Yle+ ++++ + r+++d+a++ p FUN_001671-T2 1521 TLEASLDNSPGDVALWIKLAKLQLHQASDGdNVDTCLDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSP- 1609 56888999***************9999876155556789999999*****************************************999. PP HAT_Syf1_CNRKL1_N 127 tqheriWelylkfaksae 144 +W yl++ k+ FUN_001671-T2 1610 --TYSVWWKYLEYSKTYF 1625 ..678*******998754 PP == domain 3 score: 0.1 bits; conditional E-value: 0.38 HAT_Syf1_CNRKL1_N 12 npysvkaWlrYiehkkkkksleelalvyeRAlkelprsy 50 np v Wl + ++ +++ + vye+Al++ ++ FUN_001671-T2 1813 NPSVVVLWLCLAALEDDRQGGADARQVYEKALEKCRGHA 1851 555666677777776666666667777777777666554 PP == domain 4 score: 4.6 bits; conditional E-value: 0.016 HAT_Syf1_CNRKL1_N 50 yklWkaYlklrvkqvkkknpvkkeeeyekvnnlferalvlln 91 lW++Yl ++++ +++ + +++ +++++l +r+l+ ++ FUN_001671-T2 1986 QTLWTEYLLYQRSKFMQREK-SFTPHQQHMSELVNRCLMSVS 2026 579*****999999988875.57899999999999*999876 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00011 HAT_Syf1_CNRKL1_N 11 rnpysvkaWlrYiehkkkkksleelalvyeRAlkelprsyklWkaYlklrvkq 63 np+s+++W i ++ +++ ++e +y+ A + lp lWk++l + +q FUN_001671-T2 2105 DNPFSISMWKVAIAIELQRNCVHEARKMYQQATEILPFAATLWKDFLMFELAQ 2157 699********************************************987665 PP >> Suf Suppressor of forked protein (Suf) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.3 0.001 2.3 4 95 .. 1520 1622 .. 1517 1629 .. 0.66 2 ! 5.2 0.0 0.0038 8.7 283 354 .. 1820 1891 .. 1790 1954 .. 0.73 3 ? 1.4 0.1 0.056 1.3e+02 85 135 .. 1987 2042 .. 1964 2071 .. 0.71 4 ! 5.7 0.1 0.0027 6.2 37 89 .. 2062 2115 .. 2039 2118 .. 0.86 5 ! 18.4 0.0 3.7e-07 0.00086 10 76 .. 2103 2170 .. 2094 2178 .. 0.88 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.001 Suf 4 gkledrieenpldieawleLik..eaqsk.........dkieevrevyekllkqFplaarlWkayieaelkrkefeeveklfsrcLlkvldveL 86 ++le++++++p d+ w +L k +q++ d+++++ ++ ++ l++ ++ +lW +y+e +r + +e ++ ++ ++ FUN_001671-T2 1520 ETLEASLDNSPGDVALWIKLAKlqLHQASdgdnvdtclDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSPTYSV 1613 6677777777777777777744112333233333333345666666777777777777888888888888888888888888888888888888 PP Suf 87 WklYldYvr 95 W Yl+Y + FUN_001671-T2 1614 WWKYLEYSK 1622 888888855 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0038 Suf 283 WyeaaeyleesskeeeaaklleraikalpesllLtfklaeleEsrnkiekvkeiyeklldallkelkklkee 354 W+ a ++ + +a +++e+a++ ++ ++++++ a ++ ++n++e++ ++ +k++++ +++++ ++e FUN_001671-T2 1820 WLCLAALEDDRQGGADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLRKCVQYKFASVSQSSKE 1891 555555555555557788888888888888888888888888888888888888888885555554444443 PP == domain 3 score: 1.4 bits; conditional E-value: 0.056 Suf 85 eLWklYldYvr.....rkndlitggeearetvikAyefalekigldieSgsiwadY 135 LW+ Yl Y r r++ ++ +++++ e v + + ++ + +S+ +w+dY FUN_001671-T2 1987 TLWTEYLLYQRskfmqREKSFTPHQQHMSELVNRCLMSVSTSSSFPFSSSAVWQDY 2042 59999998866111114455556666666777777777777777999999999999 PP == domain 4 score: 5.7 bits; conditional E-value: 0.0027 Suf 37 revyekllkqFplaarlWkayieaelkrkefeeveklfsrcLlkvl.dveLWkl 89 e ++k+ k+Fp +a+l + ++e+++k f+ +k+ + L+++ ++++Wk+ FUN_001671-T2 2062 SEEFQKFRKIFPGSASLAMWSCKHEMEKKSFDLSKKICASFLSDNPfSISMWKV 2115 5679***************************************96549****97 PP == domain 5 score: 18.4 bits; conditional E-value: 3.7e-07 Suf 10 ieenpldieawleLikeaqskdkieevrevyekllkqFplaarlWkayieaelkrk.efeeveklfsr 76 +++np+ i+ w i +++ ++e+r++y++ +++ p+aa+lWk + el++k + ++v++++++ FUN_001671-T2 2103 LSDNPFSISMWKVAIAIELQRNCVHEARKMYQQATEILPFAATLWKDFLMFELAQKgDGAAVQEIMAK 2170 6789*************************************************987245678888876 PP >> zf-C3H1 Putative zinc-finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 6.0 3.3e-09 7.7e-06 1 21 [. 1351 1370 .. 1351 1370 .. 0.97 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 3.3e-09 zf-C3H1 1 LCpyElaGGvCNDesCefQHF 21 LC ++l G +CNDe+C+fQH+ FUN_001671-T2 1351 LCNFDLQG-KCNDEDCKFQHL 1370 8*******.***********6 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.02 46 2 26 .. 1522 1546 .. 1521 1555 .. 0.90 2 ? -2.8 0.0 7 1.6e+04 2 13 .. 1601 1612 .. 1600 1614 .. 0.89 3 ? -1.1 0.0 2 4.7e+03 5 22 .. 1809 1826 .. 1808 1832 .. 0.86 4 ! 10.4 0.1 0.00041 0.95 2 33 .. 1840 1871 .. 1839 1872 .. 0.95 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.02 TPR_17 2 ylkaleldPnnadayynLArlllnn 26 ++ +l++ P ++ ++ LA l+l++ FUN_001671-T2 1522 LEASLDNSPGDVALWIKLAKLQLHQ 1546 5789*****************9976 PP == domain 2 score: -2.8 bits; conditional E-value: 7 TPR_17 2 ylkaleldPnna 13 +++a+e P+++ FUN_001671-T2 1601 CDQAVEFSPTYS 1612 89********87 PP == domain 3 score: -1.1 bits; conditional E-value: 2 TPR_17 5 aleldPnnadayynLArl 22 l+ +P + ++ +LA l FUN_001671-T2 1809 LLKDNPSVVVLWLCLAAL 1826 68899999*******986 PP == domain 4 score: 10.4 bits; conditional E-value: 0.00041 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 y+kale++ +a + y Ar++l++++ e Al FUN_001671-T2 1840 YEKALEKCRGHAMVAYSAARFYLEKNEVEAAL 1871 9***************************9997 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.61 1.4e+03 17 44 .. 1519 1546 .. 1517 1555 .. 0.90 2 ? 2.2 0.0 0.16 3.7e+02 5 26 .. 1662 1683 .. 1660 1691 .. 0.87 3 ! 9.9 3.1 0.00061 1.4 13 56 .. 1833 1876 .. 1823 1882 .. 0.91 4 ? -3.5 0.0 9.7 2.2e+04 14 25 .. 2127 2138 .. 2121 2147 .. 0.71 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.61 TPR_16 17 aaaleaalrrnPeaaaAllglGlallrq 44 ++ lea l++ P ++a + l+ + l+q FUN_001671-T2 1519 IETLEASLDNSPGDVALWIKLAKLQLHQ 1546 68899*******************9997 PP == domain 2 score: 2.2 bits; conditional E-value: 0.16 TPR_16 5 raalaagdyddAaaaleaalrr 26 +++l++g++ A+ ++aal + FUN_001671-T2 1662 QLELYSGHFKSALSVFKAALGK 1683 6889***************976 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00061 TPR_16 13 yddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayra 56 +dA+ +e al++ +a ++ ++ +l+++++++A+a++r+ FUN_001671-T2 1833 GADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLRK 1876 589************99***********************9986 PP == domain 4 score: -3.5 bits; conditional E-value: 9.7 TPR_16 14 ddAaaaleaalr 25 +A++ +++a++ FUN_001671-T2 2127 HEARKMYQQATE 2138 689999999986 PP >> zf-CCCH_12 CCCH zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 1.9 0.00011 0.25 14 27 .. 1356 1369 .. 1351 1371 .. 0.90 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00011 zf-CCCH_12 14 LrGsCengdCeYdH 27 L+G+C+++dC+++H FUN_001671-T2 1356 LQGKCNDEDCKFQH 1369 9************* PP >> DUF7648 Domain of unknown function (DUF7648) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 9.1 2.1e+04 31 57 .. 902 928 .. 891 929 .. 0.73 2 ? 10.9 0.0 0.00025 0.57 13 42 .. 1417 1446 .. 1411 1451 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 9.1 DUF7648 31 dlrKpngeryayssylhAvldcLRnrs 57 +l +++ ++ +s+l+ +l LR+++ FUN_001671-T2 902 NLANHKKLIQQDKSFLDKILSELRDKN 928 556666666677899999999999987 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00025 DUF7648 13 nknitYeelCdavlqhwkdlrKpngeryay 42 +++++YeelC + + k+ rK+ng y + FUN_001671-T2 1417 GEKMSYEELCILIVNEIKKQRKANGPYYVH 1446 679*********************988876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 2.3 5.4e+03 20 29 .. 1836 1845 .. 1834 1845 .. 0.89 2 ? 8.6 0.3 0.0014 3.3 5 31 .. 1855 1881 .. 1853 1883 .. 0.90 3 ? -0.7 0.0 1.4 3.2e+03 18 30 .. 2127 2139 .. 2126 2141 .. 0.90 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.3 TPR_8 20 Akeyyekale 29 A+++yekale FUN_001671-T2 1836 ARQVYEKALE 1845 899*****97 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0014 TPR_8 5 ynlGliylklgdyeeAkeyyekaleld 31 y ++ yl++++ e+A ++++k+++++ FUN_001671-T2 1855 YSAARFYLEKNEVEAALAVLRKCVQYK 1881 77899******************9875 PP == domain 3 score: -0.7 bits; conditional E-value: 1.4 TPR_8 18 eeAkeyyekalel 30 +eA++ y++a+e+ FUN_001671-T2 2127 HEARKMYQQATEI 2139 59********997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2226 (0.0871403); expected 510.9 (0.02) Passed bias filter: 521 (0.0203954); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.75u 0.41s 00:00:01.15 Elapsed: 00:00:00.43 # Mc/sec: 20589.16 // Query: FUN_001671-T3 [L=2167] Description: FUN_001671 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-12 45.5 8.5 0.11 13.8 0.0 7.4 7 TPR_14 Tetratricopeptide repeat 1.3e-09 38.7 3.0 0.016 16.0 0.8 5.6 5 TPR_19 Tetratricopeptide repeat 5.6e-08 33.5 9.5 0.018 15.6 0.3 4.9 5 HAT_PRP39_N PRP39 N-terminal HAT repeat 2e-06 27.9 6.0 7.6e-06 26.1 6.0 2.1 1 zf-C3H1 Putative zinc-finger domain 7.1e-05 23.1 10.0 0.00027 21.3 0.1 4.4 5 HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-ter 0.00042 20.8 0.1 0.94 10.4 0.1 4.0 4 TPR_17 Tetratricopeptide repeat 0.0017 19.2 1.5 1.4 9.9 3.1 3.5 3 TPR_16 Tetratricopeptide repeat ------ inclusion threshold ------ 0.096 12.9 1.9 0.25 11.6 1.9 1.7 1 zf-CCCH_12 CCCH zinc finger domain 0.15 12.8 0.2 0.57 10.9 0.0 2.1 2 DUF7648 Domain of unknown function (DUF7648) 1.4 9.7 2.6 3.3 8.6 0.3 2.8 2 TPR_8 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.013 33 21 44 .] 1519 1542 .. 1517 1542 .. 0.93 2 ! 6.5 0.1 0.0093 24 15 44 .] 1558 1587 .. 1556 1587 .. 0.91 3 ! 9.5 0.1 0.001 2.6 2 41 .. 1579 1618 .. 1578 1619 .. 0.93 4 ? 5.0 0.0 0.029 73 2 29 .. 1655 1682 .. 1654 1689 .. 0.90 5 ! 13.8 0.0 4.3e-05 0.11 3 44 .] 1785 1826 .. 1783 1826 .. 0.93 6 ! 10.4 0.9 0.00051 1.3 2 43 .. 1818 1859 .. 1817 1860 .. 0.89 7 ? 4.7 0.4 0.036 91 5 29 .. 1855 1879 .. 1851 1882 .. 0.90 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.013 TPR_14 21 lelleralaldPddpeawlalarl 44 +e le+ l P+d ++w++la+l FUN_001671-T3 1519 IETLEASLDNSPGDVALWIKLAKL 1542 6889******************96 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0093 TPR_14 15 GdpdeAlelleralaldPddpeawlalarl 44 ++ ++Al l r+l+ + +++++wl++ +l FUN_001671-T3 1558 DNVSQALSTLSRGLEENANSEALWLEYLEL 1587 67899********************99875 PP == domain 3 score: 9.5 bits; conditional E-value: 0.001 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlal 41 ++wl +++++ + + de +e+ ++a++ P++ +w+ l FUN_001671-T3 1579 ALWLEYLELYSSRCNQDELREICDQAVEFSPTYSVWWKYL 1618 79******************************99998765 PP == domain 4 score: 5.0 bits; conditional E-value: 0.029 TPR_14 2 eawlalarallalGdpdeAlellerala 29 e++l+ ++++l G+++ Al ++++al FUN_001671-T3 1655 EILLYFVQLELYSGHFKSALSVFKAALG 1682 789999********************85 PP == domain 5 score: 13.8 bits; conditional E-value: 4.3e-05 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlalarl 44 +++ l+++++a G+ d A+ + +l+ +P+ +wl la l FUN_001671-T3 1785 LYKNLIALEMAYGRIDSARGICHHLLKDNPSVVVLWLCLAAL 1826 6778999********************************976 PP == domain 6 score: 10.4 bits; conditional E-value: 0.00051 TPR_14 2 eawlalarallalGdpdeAlelleralaldPddpeawlalar 43 +wl la+++ ++ ++A++++e+al+++ +++ + + +ar FUN_001671-T3 1818 VLWLCLAALEDDRQGGADARQVYEKALEKCRGHAMVAYSAAR 1859 68****************************999888776665 PP == domain 7 score: 4.7 bits; conditional E-value: 0.036 TPR_14 5 lalarallalGdpdeAlellerala 29 + +ar++l+ ++ ++Al++l+++++ FUN_001671-T3 1855 YSAARFYLEKNEVEAALAVLRKCVQ 1879 6789******************975 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.8 0.0 0.0094 24 11 38 .. 1519 1546 .. 1517 1548 .. 0.92 2 ! 6.1 0.0 0.0078 20 8 57 .. 1561 1610 .. 1558 1617 .. 0.83 3 ? 1.0 0.0 0.31 7.8e+02 26 60 .. 1655 1690 .. 1649 1698 .. 0.65 4 ? 3.6 0.0 0.048 1.2e+02 27 56 .. 1785 1814 .. 1760 1824 .. 0.80 5 ! 16.0 0.8 6.1e-06 0.016 8 49 .. 1834 1875 .. 1833 1880 .. 0.96 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0094 TPR_19 11 lalLeqalaedPdnaearllLArallal 38 ++ Le+ l+ +P++ ++++ LA+++l++ FUN_001671-T3 1519 IETLEASLDNSPGDVALWIKLAKLQLHQ 1546 57899********************987 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0078 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadpd 57 +Al+ L + l+e+ ++ +++l + +++ + de +++ +++ + p FUN_001671-T3 1561 SQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSPT 1610 689999********************999999988888888888776665 PP == domain 3 score: 1.0 bits; conditional E-value: 0.31 TPR_19 26 earllLArallalgrldeAealLaalpaadpdd.pe 60 e++l +++ l +g+++ A +++a++ ++ +d +e FUN_001671-T3 1655 EILLYFVQLELYSGHFKSALSVFKAALGKKVQDqSE 1690 566666666666677777777776666666666555 PP == domain 4 score: 3.6 bits; conditional E-value: 0.048 TPR_19 27 arllLArallalgrldeAealLaalpaadp 56 ++ +L+ + +a gr+d A+ + l++++p FUN_001671-T3 1785 LYKNLIALEMAYGRIDSARGICHHLLKDNP 1814 455889999*************99999998 PP == domain 5 score: 16.0 bits; conditional E-value: 6.1e-06 TPR_19 8 deAlalLeqalaedPdnaearllLArallalgrldeAealLa 49 ++A++++e+al++ ++a +++ Ar++l+ +++++A a+L FUN_001671-T3 1834 ADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLR 1875 69*************************************996 PP >> HAT_PRP39_N PRP39 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.3 7.1e-06 0.018 7 98 .. 1526 1627 .. 1516 1693 .. 0.55 2 ! 8.7 0.0 0.00093 2.4 19 81 .. 1788 1850 .. 1778 1920 .. 0.79 3 ! 6.0 0.0 0.0062 16 84 138 .. 1945 1999 .. 1939 2023 .. 0.84 4 ? 4.3 0.1 0.022 55 83 131 .. 1987 2042 .. 1964 2047 .. 0.65 5 ? 5.0 0.2 0.013 32 35 93 .. 2063 2121 .. 2057 2138 .. 0.82 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.1e-06 HAT_PRP39_N 7 vkenpedfnaWtkL..lqyveq.........endiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYl 89 ++++p d+ W+kL lq + +++++a ++ ++ L+e + w Y +l + +n+++ +e+++++v+ p +W +Yl FUN_001671-T3 1526 LDNSPGDVALWIKLakLQLHQAsdgdnvdtcLDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSP-TYSVWWKYL 1618 555666666666663333333333333322225555555666666666777777777777777777777777777777777665.345677777 PP HAT_PRP39_N 90 eflketlek 98 e+ k+ ++k FUN_001671-T3 1619 EYSKTYFAK 1627 777766543 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00093 HAT_PRP39_N 19 kLlqyveqendiekareaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaipls 81 +L++ +i++ar + +++L+ P ++ w a le + ++a++vye+++++++ + FUN_001671-T3 1788 NLIALEMAYGRIDSARGICHHLLKDNPSVVVLWLCLAALEDDRQGGADARQVYEKALEKCRGH 1850 566665566788999999999999999999999999999999999999999999999887654 PP == domain 3 score: 6.0 bits; conditional E-value: 0.0062 HAT_PRP39_N 84 lWlhYleflketlekedpeseekirelferavaavGldfrsdklWdkYiefekeq 138 lWl+Y+ +l + + ++ + +++fe+av++ + ++lW++Y+ +++++ FUN_001671-T3 1945 LWLSYCLLLEISPPCPTVWDNVSAESAFETAVHSPLDRQDVQTLWTEYLLYQRSK 1999 9*****9998776666677788999************************997654 PP == domain 4 score: 4.3 bits; conditional E-value: 0.022 HAT_PRP39_N 83 dlWlhYleflketleked...peseekirelferavaavGld....frsdklWdkY 131 lW++Yl + ++++ +++ + +++++ el +r++ +v + f+s+ +W++Y FUN_001671-T3 1987 TLWTEYLLYQRSKFMQREksfTPHQQHMSELVNRCLMSVSTSssfpFSSSAVWQDY 2042 48999999988877554412223467788888888777766433337799999988 PP == domain 5 score: 5.0 bits; conditional E-value: 0.013 HAT_PRP39_N 35 eaydaFLaeyPlcygYwkkYadlekrkgnlekaeevyergvkaiplsvdlWlhYleflk 93 e +++F + +P + ++e++k++ + +++++ ++ p s+ +W Y + l FUN_001671-T3 2063 EEFQKFRKIFPGSASLAMWSCKHEMEKKSFDLSKKICASFLSDNPFSISMWKVYHSPLA 2121 56788888888777666666789999999***********************9987655 PP >> zf-C3H1 Putative zinc-finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 6.0 3e-09 7.6e-06 1 21 [. 1351 1370 .. 1351 1370 .. 0.97 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 3e-09 zf-C3H1 1 LCpyElaGGvCNDesCefQHF 21 LC ++l G +CNDe+C+fQH+ FUN_001671-T3 1351 LCNFDLQG-KCNDEDCKFQHL 1370 8*******.***********6 PP >> HAT_Syf1_CNRKL1_N Pre-mRNA-splicing factor Syf1/CNRKL1 N-terminal HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.2 1.3 3.3e+03 41 84 .. 836 879 .. 818 881 .. 0.82 2 ! 21.3 0.1 1e-07 0.00027 38 144 .. 1521 1625 .. 1509 1637 .. 0.86 3 ? 0.1 0.0 0.34 8.8e+02 12 50 .. 1813 1851 .. 1807 1882 .. 0.61 4 ? 4.6 0.1 0.014 36 50 91 .. 1986 2026 .. 1937 2046 .. 0.78 5 ? -3.5 0.0 4.5 1.1e+04 25 56 .. 2085 2116 .. 2075 2123 .. 0.67 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.3 HAT_Syf1_CNRKL1_N 41 RAlkelprsyklWkaYlklrvkqvkkknpvkkeeeyekvnnlfe 84 A++++p+ +k ++ lk+r ++ +k+++ +k ++++++++++e FUN_001671-T3 836 DAMDHMPEQMKNEYRRLKERLAHREKTKQQDKGDRMKSTSEVHE 879 58999999999999999***999999999998899999888887 PP == domain 2 score: 21.3 bits; conditional E-value: 1e-07 HAT_Syf1_CNRKL1_N 38 vyeRAlkelprsyklWkaYlklrvkqvkkk.npvkkeeeyekvnnlferalvllnkmpriWldYlefllkqkkvtktrrtfdraLralpi 126 +e +l++ p+ + lW + kl+ +q+++ n+ + ++++++ ++ r l + +Wl+Yle+ ++++ + r+++d+a++ p FUN_001671-T3 1521 TLEASLDNSPGDVALWIKLAKLQLHQASDGdNVDTCLDNVSQALSTLSRGLEENANSEALWLEYLELYSSRCNQDELREICDQAVEFSP- 1609 56888999***************9999876155556789999999*****************************************999. PP HAT_Syf1_CNRKL1_N 127 tqheriWelylkfaksae 144 +W yl++ k+ FUN_001671-T3 1610 --TYSVWWKYLEYSKTYF 1625 ..678*******998754 PP == domain 3 score: 0.1 bits; conditional E-value: 0.34 HAT_Syf1_CNRKL1_N 12 npysvkaWlrYiehkkkkksleelalvyeRAlkelprsy 50 np v Wl + ++ +++ + vye+Al++ ++ FUN_001671-T3 1813 NPSVVVLWLCLAALEDDRQGGADARQVYEKALEKCRGHA 1851 555666677777776666666667777777777666554 PP == domain 4 score: 4.6 bits; conditional E-value: 0.014 HAT_Syf1_CNRKL1_N 50 yklWkaYlklrvkqvkkknpvkkeeeyekvnnlferalvlln 91 lW++Yl ++++ +++ + +++ +++++l +r+l+ ++ FUN_001671-T3 1986 QTLWTEYLLYQRSKFMQREK-SFTPHQQHMSELVNRCLMSVS 2026 579*****999999988875.57899999999999*999876 PP == domain 5 score: -3.5 bits; conditional E-value: 4.5 HAT_Syf1_CNRKL1_N 25 hkkkkksleelalvyeRAlkelprsyklWkaY 56 h+++kks + + l++ p s +Wk Y FUN_001671-T3 2085 HEMEKKSFDLSKKICASFLSDNPFSISMWKVY 2116 44445566666667777788888888888888 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.018 45 2 26 .. 1522 1546 .. 1521 1555 .. 0.90 2 ? -2.8 0.0 6.3 1.6e+04 2 13 .. 1601 1612 .. 1600 1614 .. 0.89 3 ? -1.1 0.0 1.8 4.5e+03 5 22 .. 1809 1826 .. 1808 1833 .. 0.86 4 ! 10.4 0.1 0.00037 0.94 2 33 .. 1840 1871 .. 1839 1872 .. 0.95 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.018 TPR_17 2 ylkaleldPnnadayynLArlllnn 26 ++ +l++ P ++ ++ LA l+l++ FUN_001671-T3 1522 LEASLDNSPGDVALWIKLAKLQLHQ 1546 5789*****************9976 PP == domain 2 score: -2.8 bits; conditional E-value: 6.3 TPR_17 2 ylkaleldPnna 13 +++a+e P+++ FUN_001671-T3 1601 CDQAVEFSPTYS 1612 89********87 PP == domain 3 score: -1.1 bits; conditional E-value: 1.8 TPR_17 5 aleldPnnadayynLArl 22 l+ +P + ++ +LA l FUN_001671-T3 1809 LLKDNPSVVVLWLCLAAL 1826 68899999*******986 PP == domain 4 score: 10.4 bits; conditional E-value: 0.00037 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAl 33 y+kale++ +a + y Ar++l++++ e Al FUN_001671-T3 1840 YEKALEKCRGHAMVAYSAARFYLEKNEVEAAL 1871 9***************************9997 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.55 1.4e+03 17 44 .. 1519 1546 .. 1517 1555 .. 0.90 2 ? 2.2 0.0 0.14 3.6e+02 5 26 .. 1662 1683 .. 1660 1691 .. 0.87 3 ! 9.9 3.1 0.00055 1.4 13 56 .. 1833 1876 .. 1823 1882 .. 0.91 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.55 TPR_16 17 aaaleaalrrnPeaaaAllglGlallrq 44 ++ lea l++ P ++a + l+ + l+q FUN_001671-T3 1519 IETLEASLDNSPGDVALWIKLAKLQLHQ 1546 68899*******************9997 PP == domain 2 score: 2.2 bits; conditional E-value: 0.14 TPR_16 5 raalaagdyddAaaaleaalrr 26 +++l++g++ A+ ++aal + FUN_001671-T3 1662 QLELYSGHFKSALSVFKAALGK 1683 6889***************976 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00055 TPR_16 13 yddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayra 56 +dA+ +e al++ +a ++ ++ +l+++++++A+a++r+ FUN_001671-T3 1833 GADARQVYEKALEKCRGHAMVAYSAARFYLEKNEVEAALAVLRK 1876 589************99***********************9986 PP >> zf-CCCH_12 CCCH zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 1.9 9.6e-05 0.25 14 27 .. 1356 1369 .. 1351 1371 .. 0.90 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 9.6e-05 zf-CCCH_12 14 LrGsCengdCeYdH 27 L+G+C+++dC+++H FUN_001671-T3 1356 LQGKCNDEDCKFQH 1369 9************* PP >> DUF7648 Domain of unknown function (DUF7648) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 8.1 2.1e+04 31 57 .. 902 928 .. 891 929 .. 0.73 2 ? 10.9 0.0 0.00022 0.57 13 42 .. 1417 1446 .. 1411 1451 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 8.1 DUF7648 31 dlrKpngeryayssylhAvldcLRnrs 57 +l +++ ++ +s+l+ +l LR+++ FUN_001671-T3 902 NLANHKKLIQQDKSFLDKILSELRDKN 928 556666666677899999999999987 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00022 DUF7648 13 nknitYeelCdavlqhwkdlrKpngeryay 42 +++++YeelC + + k+ rK+ng y + FUN_001671-T3 1417 GEKMSYEELCILIVNEIKKQRKANGPYYVH 1446 679*********************988876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 2.1 5.4e+03 20 29 .. 1836 1845 .. 1834 1845 .. 0.89 2 ? 8.6 0.3 0.0013 3.3 5 31 .. 1855 1881 .. 1853 1883 .. 0.90 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2.1 TPR_8 20 Akeyyekale 29 A+++yekale FUN_001671-T3 1836 ARQVYEKALE 1845 899*****97 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0013 TPR_8 5 ynlGliylklgdyeeAkeyyekaleld 31 y ++ yl++++ e+A ++++k+++++ FUN_001671-T3 1855 YSAARFYLEKNEVEAALAVLRKCVQYK 1881 77899******************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2817 (0.110276); expected 510.9 (0.02) Passed bias filter: 767 (0.0300254); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 21 (0.000822079); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.78u 0.44s 00:00:01.22 Elapsed: 00:00:00.44 # Mc/sec: 20052.48 // Query: FUN_001672-T1 [L=376] Description: FUN_001672 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-44 150.7 22.0 9.7e-44 150.3 22.0 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.079 13.0 0.2 0.15 12.2 0.2 1.4 1 Potex_coat Potexvirus coat protein Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 150.3 22.0 7.6e-48 9.7e-44 1 260 [] 43 312 .. 43 312 .. 0.90 Alignments for each domain: == domain 1 score: 150.3 bits; conditional E-value: 7.6e-48 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr.nkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvf........gevlCklvtaldvvnltasillltaisiDRYla 86 gN+++i++++ + + + ++ ++++n+avaDll++++++ + +++++ l +++f g +lCk++ +l+ +++ +s+++l+ai+ +R+ a FUN_001672-T1 43 GNCVLITALCGnYSRCHAVMRYYIVNMAVADLLTTVVNTGVQVYHYAlLVMHKQFvwlvdgitGVALCKMIAFLQGTAIACSVFTLIAIATNRFRA 138 8*********96777888******************999988877654445555555888888********************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 87 IvkplkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtl 180 +v p+++ ++++ra+++i vvW+ a++ + p+l+ + k++ +ee+ C+ d++ +++ +++ yt++l++ +l+pll+++ +y+ i+ ++ FUN_001672-T1 139 VVFPFQR--TMRNSRAYLVITVVWISAFATASPMLYAMRLKNV---NEESYCMEDWEPllDNQSSRRQYTMVLFFSLYLCPLLLLALLYSIIALKV 229 ******9..7999***********************9999988...99********996555559999*****9999999**************** PP xxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 181 rksakkeks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + + ++ ++ ++++++k++ + ++vv+vf lcwlP+ + l+l+ l ++ ++++e + + l+++++ns++NP+iY FUN_001672-T1 230 WGRTAPGQTttvNQVIEMERKKKIMMICITVVLVFSLCWLPFYVYLILEFLGAFNDGCNTPEYLAFLGLFFGHANSAINPFIY 312 ****999995555555667788***********************99999977788999999999****************** PP >> Potex_coat Potexvirus coat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.2 1.2e-05 0.15 26 77 .. 127 181 .. 117 186 .. 0.80 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.2e-05 Potex_coat 26 slterattsftrksfptlknmGd.rafqvvaakivv..vsaapllyqarlyspgd 77 +l at f+ fp + m + ra+ v+++ + ++a+p+ly rl + ++ FUN_001672-T1 127 TLIAIATNRFRAVVFPFQRTMRNsRAYLVITVVWISafATASPMLYAMRLKNVNE 181 777889999**********996449****998654312689*********98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (376 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1239 (0.0485026); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 3623.03 // Query: FUN_001673-T1 [L=121] Description: FUN_001673 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0093 16.1 0.1 0.014 15.5 0.1 1.3 1 SAP SAP domain ------ inclusion threshold ------ 0.074 13.7 0.0 0.1 13.2 0.0 1.1 1 Rsbr_N Rsbr N terminal Domain annotation for each model (and alignments): >> SAP SAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.1 1.1e-06 0.014 3 37 .] 30 66 .. 28 66 .. 0.95 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.1e-06 SAP 3 skltvseLKeeLkkrGLptsGk..KaeLieRLkeyle 37 s+l+ eL+ L+ rG + +G K L++R++ey++ FUN_001673-T1 30 SSLKNEELRFWLRCRGDSLKGLntKDLLVKRVEEYVK 66 89*********************************75 PP >> Rsbr_N Rsbr N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 7.8e-06 0.1 3 49 .. 52 98 .. 51 106 .. 0.91 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 7.8e-06 Rsbr_N 3 enkdelvkewlkelkelrkeeylqkisdelyeetskefvdlilssvk 49 + kd lvk+ ++ +k+ r+++ ++ +de+y++ k v++++ss FUN_001673-T1 52 NTKDLLVKRVEEYVKSGRDQMAIDPDPDEIYTKRKKRIVNVMMSSTP 98 57999**************************************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 513 (0.0200822); expected 510.9 (0.02) Passed bias filter: 466 (0.0182423); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1201.40 // Query: FUN_001674-T1 [L=364] Description: FUN_001674 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-48 164.0 16.3 9e-48 163.5 16.3 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 9.8e-15 55.1 14.5 1.9e-14 54.2 14.5 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 2.9e-08 33.8 17.3 7.6e-08 32.5 17.3 1.6 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 9.2e-05 22.6 16.3 0.00046 20.3 16.0 2.3 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 163.5 16.3 1.4e-51 9e-48 1 260 [] 36 305 .. 36 305 .. 0.89 Alignments for each domain: == domain 1 score: 163.5 bits; conditional E-value: 1.4e-51 xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrt.ptnifllnLavaDllvlllvlpfalvyal.legdwvf.......gevlCklvtaldvvnltasillltaisiDRYlaI 87 gN+l+i+v+++n++lr+ + n +++++avaDll++++++ + ++ + + ++ f + +lCk++ +++ ++l +s+l+ltai+++R+ a+ FUN_001674-T1 36 GNVLIIVVVAKNQRLRSaTINRLIVSMAVADLLTSIFNMTVEISIYTkQATGQRFvwfkgpgSGFLCKIIPFIQGLSLASSVLTLTAIAVNRFFAV 131 8****************555****************988888854442223333344777767789****************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 88 vkplkykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlr 181 + plk++ + ++ ++i+++W+++++++ p l+ +++ +e +C+ +++ + +t++++ytl+l++ +++p++vi+v+y+ i+r+++ FUN_001674-T1 132 FFPLKMSD-LSYPLTSIVIGLIWLVSVAMASPLLYAQKVIEE---DCGVQCMEQWSPafNGDTSPKIYTLMLLISLYVIPVFVITVLYTAIVRKVW 223 ******76.88899*******************997766544...99********99777788********************************* PP xxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 182 ksakkeks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 k++ + ++ + +++++l++l+++vvvf+lcwlPy + l+l+ ll + +++ +++ + l+l+++ns++NP iY FUN_001674-T1 224 KRQVPGNIiapNRLVELLTKKRVLRMLITIVVVFALCWLPYYTYLFLNFLLLSPPHQIARVNVMFVGLFLGHANSAINPCIY 305 ***998764445666667778*****************************9999**************************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.2 14.5 2.9e-18 1.9e-14 2 254 .. 31 317 .. 30 319 .. 0.75 Alignments for each domain: == domain 1 score: 54.2 bits; conditional E-value: 2.9e-18 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrsks.siLicvqcladllclvgelvfvvllltgtqlkreeCFl........l.iivyvfgl.taqsvllL.vigiD 85 ++++ GNvl+i++++k+++Lrs + + Li+ ++adll ++++ ++ t++ + ++ ++ ii+ + gl +a+svl L +i++ FUN_001674-T1 31 FISTLGNVLIIVVVAKNQRLRSATiNRLIVSMAVADLLTSIFNMTVEISIYTKQATGQRFVWFkgpgsgflCkIIPFIQGLsLASSVLTLtAIAVN 126 899******************975399***********************9999999987543222222113244444454257778877479*** PP 7TM_GPCR_Srsx 86 lliavkfPirYrllskek..YllillifpvlyssiilvlgflqrddetiivCappl..alagkaseiftlssliinvivllvylvliiilkkkkek 177 +++av+fP++ + ls ++ l+ ++ + ++ l++ + +++++ + C+ a++g++s + +++l+i++ v+ v++++++ ++ FUN_001674-T1 127 RFFAVFFPLKMSDLSYPLtsIVIGLIWLVSVAMASPLLYAQKVIEEDCGVQCMEQWspAFNGDTSPKIYTLMLLISLYVIPVFVITVLYTAIVRKV 222 ************998765534444444444444456788888889998889986542389***999999999***********9999885555555 PP 7TM_GPCR_Srsx 178 ................kkssskkvlkslkvtvvififgWftsti.lntvllalteseevekliqayagilv.llsfsqnffVtywrsseYrkafr 254 + + k+vl+ l + vv+f ++W+ + l+ +l l+ +++++ + +g+++ +++ n ++ + ++eYr+ f+ FUN_001674-T1 223 wkrqvpgniiapnrlvELLTKKRVLRMLITIVVVFALCWLPYYTyLFLNFLLLSPPHQIARVNVMFVGLFLgHANSAINPCIYAIFNKEYRNGFI 317 56699*********9999999******************754330333344445555555555566665551567778999***********986 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 17.3 1.2e-11 7.6e-08 3 311 .. 26 315 .. 24 321 .. 0.81 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 1.2e-11 7TM_GPCR_Srw 3 efilsivgviinifHliiLtr.ksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgv 97 +++ +++ + n++ +++ + + +r+ +in l++++a++D+lt ++++ +i + ++ + ++ + + + +l i+ +++ +s s+ FUN_001674-T1 26 YVVIFFISTLGNVLIIVVVAKnQRLRSATINRLIVSMAVADLLTSIFNMTVEISIYTKQATGQRFVWFKGPGSGFLCKIIPFIQGLSLASSVLTLT 121 5688999999***99999986257*****************************8888888888888778778888888899*************** PP 7TM_GPCR_Srw 98 lmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifl 193 ++A+ R++ v +pl+ ++ ls p ++++i li l+ ++ s l y++ i+e+ +C e + s +f n ki++ FUN_001674-T1 122 AIAVNRFFAVFFPLK--MSDLSYPLTSIVIGLIWLVSVAMASPLLYAQKVIEEDC-GV----QCM---E---------QWSPAF--NGDTSPKIYT 196 ***********9985..679*******9999988888888888888887776333.33....475...2.........233332..2334446677 PP 7TM_GPCR_Srw 194 lidgilskiipsillpiltilLiieLrkakksrkklsksk..kneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifs 287 l+ i++ +ip +++ +l ++ +++ +k + + + ++ + +++ ++ + + ++f + lp+ + +++f++ + + + + +++++ FUN_001674-T1 197 LMLLISLYVIPVFVITVLYTAIVRKVWKRQVPGNIIAPNRlvELLTKKRVLRMLITIVVVFALCWLPYYTYLFLNFLLLSPP-HQIARVNVMFVGL 291 777788888********************99999999666343347888888888888999999999999999999988866.5555566777777 PP 7TM_GPCR_Srw 288 llltinsisHflicllmSsqYRkt 311 +l +ns++ i+ ++ +YR+ FUN_001674-T1 292 FLGHANSAINPCIYAIFNKEYRNG 315 8889******************96 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 16.0 7.2e-08 0.00046 69 185 .. 104 223 .. 27 276 .. 0.62 2 ? -1.6 0.1 0.35 2.2e+03 124 140 .. 250 265 .. 226 293 .. 0.65 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 7.2e-08 7TM_GPCR_Srx 69 liglialglYeisplsqllialNRfcavffplkyekifsiknTkiiiviiwivslifit.vly....lpegCkllynpetltwsfeeteccktisw 159 +i +i + s l+ + ia+NRf+avffplk++ + s++ T i+i +iw+vs+++ +ly + e+C + e ++ +f+ ++ k+++ FUN_001674-T1 104 IIPFIQGLSLASSVLTLTAIAVNRFFAVFFPLKMSDL-SYPLTSIVIGLIWLVSVAMASpLLYaqkvIEEDCGVQCM-EQWSPAFNGDTSPKIYTL 197 555566666777899999**************99775.9*****************955455522225689999876.455555555555555555 PP 7TM_GPCR_Srx 160 yldfllililviitlvlnlltaikli 185 +l + l++i v++++vl ++++ k+ FUN_001674-T1 198 MLLISLYVIPVFVITVLYTAIVRKVW 223 54445555555555555555555555 PP == domain 2 score: -1.6 bits; conditional E-value: 0.35 7TM_GPCR_Srx 124 ifitvlylpegCkllyn 140 + it++ ++ C+l y FUN_001674-T1 250 L-ITIVVVFALCWLPYY 265 2.333333344444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (364 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1116 (0.0436876); expected 510.9 (0.02) Passed bias filter: 431 (0.0168722); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.45s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3517.16 // Query: FUN_001675-T1 [L=476] Description: FUN_001675 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.1e-52 176.9 18.5 9.5e-52 176.5 18.5 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.1e-05 25.4 20.6 1.9e-05 24.7 20.6 1.3 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 5.9e-05 23.0 23.6 0.00068 19.5 23.4 2.5 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00035 20.9 15.7 0.00063 20.1 15.7 1.6 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.34 11.2 1.6 3.9 7.8 0.1 2.4 2 GF_recep_IV Growth factor receptor domain IV 4.1 7.9 4.4 47 4.5 0.1 2.5 2 DUF8074 Domain of unknown function (DUF8074) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.5 18.5 2.2e-55 9.5e-52 1 260 [] 91 353 .. 91 353 .. 0.93 Alignments for each domain: == domain 1 score: 176.5 bits; conditional E-value: 2.2e-55 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvf....gevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN++V++v+ rn kl+t+t+++++nLa aDll++++++ + + ++++++d f g+v+C ++++ v++ +si++lt+i+++R+++I+ p+k FUN_001675-T1 91 GNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFKTEVVGNDEAFggigGDVYCVGLIVVLNVSVSCSIFNLTVIAVERFCSIMFPFK 186 8****************************************************77777899*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe.eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakke 187 + i t ++a+++++ +Wv+++ +++p++++ ++k++ +++ C+ d++ ++ t+++++++++++l + +pll+il +y i +l+k++ ++ FUN_001675-T1 187 R--IFTLKLAKAVMVSIWVVSFSITIPFFFHIKVKDYYG-DGVFYCVEDWSPlDTVTASQVFQIVFFTLLYACPLLFILLLYLSIGVHLWKRQAQR 279 9..9*****************************999855.**********9966777**********************************99988 PP xx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 188 ks....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + ++ ++r + +++k+l++ vv+f+lcwlP +++l+++++ +++ +e ++ +llay+ns++NPiiY FUN_001675-T1 280 EIsslgYSSVRKRMTVQVTKMLVASVVAFALCWLPQHVTLFINYF---MLDRCPPEFLWFGGTLLAYANSAMNPIIY 353 7644553344444445*****************************...99999999********************* PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 20.6 4.4e-09 1.9e-05 2 254 .. 86 365 .. 85 368 .. 0.75 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 4.4e-09 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv..llltgtql.....kreeCFlliivyvfgltaqsvllLvigiDlliav 90 +++liGN+ +++++ +++kL++ ++ Li+ ++ adll+ + ++ + + + + C li+v +++ + l vi++ +++ + FUN_001675-T1 86 TISLIGNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFktEVVGNDEAfggigGDVYCVGLIVVLNVSVSCSIFNLTVIAVERFCSI 181 799*********************************998766544432133333332111113446888888888888888888899********* PP 7TM_GPCR_Srsx 91 kfPirYrllskekYllillifpvlyssiilvlgflqrdde...tiivCapplalag..kaseiftlssliin.....vivllvylvliiilkkkke 176 +fP++ k +++ i +v +s++i ++ +++ d + +C + + +as++f++ + + +++ll+yl + + l k+++ FUN_001675-T1 182 MFPFKRIFTLKLAKAVMVSIWVVSFSITIPFFFHIKVKDYygdGVFYCVEDWSPLDtvTASQVFQIVFFTLLyacplLFILLLYLSIGVHLWKRQA 277 ***98766666668899999*******998888888877545589***987765441144566666666655111114555555555444444444 PP 7TM_GPCR_Srsx 177 k...........kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafr 254 + +k+ + +v k l +vv f ++W+ + + + + + + e ++ +l+ +++ n +++++ seYrk+ + FUN_001675-T1 278 QreisslgyssvRKRMTVQVTKMLVASVVAFALCWLPQHVTLFINYFMLDRCPPE-FLWFGGTLLAYANSAMNPIIYVTFHSEYRKQCK 365 469********999999******************99888777776666665555.8888899999999*****************976 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 23.4 1.6e-07 0.00068 7 317 .. 85 369 .. 79 371 .. 0.79 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 1.6e-07 7TM_GPCR_Srw 7 sivgviinifHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlmAli 102 +++i nif l++ r ++ ++ l++ a +D+l +++++ + + ++ ++e + + + + l+++ +vs cs++ ++A+ FUN_001675-T1 85 FTISLIGNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFKTEVVG--NDEAFGG--IGGDVYCVGLIVVLNVSVSCSIFNLTVIAVE 176 5689999***********9999999***********************888887..8888766..4444444557889999*************** PP 7TM_GPCR_Srw 103 RtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifllidgi 198 R+ ++++p+++ + + k + +++ + ++s+ i+i ++f+++++++ + C e + s l t +++ +i+++ + FUN_001675-T1 177 RFCSIMFPFKRIF----TLKLAKAVMVSIWVVSFSITIPFFFHIKVKDYYGDGV--FYCV---E---------DWSPLDTVTASQVFQIVFF---T 251 ********99876....589999999999999999999*******996665433..3464...2.........2333333333444455555...3 PP 7TM_GPCR_Srw 199 lskiipsillpiltilLiieLrkakksrkkls...kskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifslllt 291 l+ +p + + +l + + L+k + +r+ +s +s +++ + + tk+ + + f + lp+ ++ ++++++ + r e l + +ll + FUN_001675-T1 252 LLYACPLLFILLLYLSIGVHLWKRQAQREISSlgySSVRKRMTVQVTKMLVASVVAFALCWLPQHVTLFINYFMLD----RCPPEFLWFGGTLLAY 343 43455555555555555678999999988888887666788999****************************9888....345666677778999* PP 7TM_GPCR_Srw 292 insisHflicllmSsqYRktvkklfg 317 +ns++ +i++++ s+YRk k +++ FUN_001675-T1 344 ANSAMNPIIYVTFHSEYRKQCKLILT 369 *******************9998775 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 15.7 1.5e-07 0.00063 3 149 .. 83 229 .. 81 370 .. 0.75 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.5e-07 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareis....feacllqlffihkfsllesa.vllamavdrf 93 lv+ i+l+Gn+ +l+v+k ++ lh ++++ la +dl ++ + ++ +v++ e + + + l+ + ++s+ s l +av+rf FUN_001675-T1 83 LVFTISLIGNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFKTEVVGNDEAFggigGDVYCVGLIVVLNVSVSCSIfNLTVIAVERF 178 7999*****************************************999999999**999652211455444555555566555541456689**** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyc 149 +i+ p++ i+t k + + ++v s+ + +p+ f ++ +++g++v yc FUN_001675-T1 179 CSIMFPFK--RIFTLKLAKAVMVSIWVVSFSITIPFFFHIKVKDYYGDGVF---YC 229 ****9986..69999999999**************************9986...44 PP >> GF_recep_IV Growth factor receptor domain IV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.1 0.00091 3.9 50 78 .. 36 64 .. 9 68 .. 0.84 2 ? 2.0 0.1 0.056 2.4e+02 102 128 .. 354 380 .. 344 388 .. 0.72 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.00091 GF_recep_IV 50 kCvkChpeCeklnesetCsgpgadeClkC 78 + +C+ C+k+++++t +g+gad+ +C FUN_001675-T1 36 RQLDCDLRCKKVEMNNTINGSGADTSSAC 64 4578*********************9999 PP == domain 2 score: 2.0 bits; conditional E-value: 0.056 GF_recep_IV 102 ifkyadeekvCekChenctegctgpee 128 + +++ +k+C+ + c++ ct+ +e FUN_001675-T1 354 VTFHSEYRKQCKLILTRCHHLCTKLSE 380 556777788898877777777776554 PP >> DUF8074 Domain of unknown function (DUF8074) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 1.6 0.023 99 8 55 .. 163 210 .. 157 214 .. 0.90 2 ? 4.5 0.1 0.011 47 26 47 .. 291 312 .. 283 331 .. 0.83 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.023 DUF8074 8 lavfvYnlgVvlsggylatqlgiedrvtllalaaVvalvWtvYfrfsi 55 ++ ++nl V+ + ++++ + +tl ++ aV+ +W+v f + i FUN_001675-T1 163 VSCSIFNLTVIAVERFCSIMFPFKRIFTLKLAKAVMVSIWVVSFSITI 210 66679************************9999********9998765 PP == domain 2 score: 4.5 bits; conditional E-value: 0.011 DUF8074 26 tqlgiedrvtllalaaVvalvW 47 + ++++ + +l+a+++++al W FUN_001675-T1 291 KRMTVQVTKMLVASVVAFALCW 312 568888999999********** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (476 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1023 (0.040047); expected 510.9 (0.02) Passed bias filter: 486 (0.0190252); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.38u 0.36s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4612.70 // Query: FUN_001676-T1 [L=86] Description: FUN_001676 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 3.8 7.5 9.3 3.8 7.5 9.3 1.0 1 SURF2 Surfeit locus protein 2 (SURF2) Domain annotation for each model (and alignments): >> SURF2 Surfeit locus protein 2 (SURF2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 9.3 0.00015 3.8 142 203 .. 20 80 .. 3 86 .] 0.59 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.00015 SURF2 142 kegewepassdeeasd.sddsmsDlypdelfteksvgeeededdkesdfetdeeeekakesde 203 +++ e+ ++++e++d sd ++s+++++ l ++ ++ ++d+k d+e++e++e +++++ FUN_001676-T1 20 ETAATEDLDTQSEDDDvSDSKDSESEDELLVEFGDASNSGENDSK--DSESEEKDELPEGARV 80 445555655555555535555566665555555555555555544..6888888887776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (86 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 879 (0.0344099); expected 510.9 (0.02) Passed bias filter: 353 (0.0138188); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.23u 0.39s 00:00:00.62 Elapsed: 00:00:00.38 # Mc/sec: 902.39 // Query: FUN_001677-T1 [L=304] Description: FUN_001677 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.03 15.0 5.3 0.063 13.9 0.4 2.4 2 DUF613 Protein of unknown function (DUF613) Domain annotation for each model (and alignments): >> DUF613 Protein of unknown function (DUF613) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.5 0.0051 1.3e+02 61 108 .. 30 77 .. 16 82 .. 0.70 2 ? 13.9 0.4 2.5e-06 0.063 27 100 .. 186 258 .. 159 283 .. 0.74 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.0051 DUF613 61 itkiikertkrykklleekkisginiifqeklkykksleneyklkerl 108 i++ r + k++ e+k i+g+ ++++ +ky + l+ ++ +e+ FUN_001677-T1 30 IIRSQDPRIQLVKRFEERKAIKGLKSVLKDAKKYAEELDVAFTYDETK 77 233333455666666667************************999875 PP == domain 2 score: 13.9 bits; conditional E-value: 2.5e-06 DUF613 27 kvgkekeniteleYilLDlflyGPlkikvseyekitkiikertkrykklleekkisginiifqeklkykkslen 100 k+ + ++i++ e++lL + G ki +k +++ + ++ +k+++ ++k+ ++ni+f+ +y k l++ FUN_001677-T1 186 KIDMALHDIQKKEWLLLEGTVCGIGKIADRTSKK-QMKYRDLRSGIKQMYPQHKVTQVNIVFDFLENYYKDLKT 258 5778889999999999999999976665555555.5555566789******************55555555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (304 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1508 (0.0590331); expected 510.9 (0.02) Passed bias filter: 593 (0.0232139); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2927.71 // Query: FUN_001678-T1 [L=275] Description: FUN_001678 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-34 118.7 9.9 5.7e-34 118.2 9.9 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 2.5e-07 30.8 14.0 7.2e-07 29.3 14.0 1.8 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 7.9e-06 26.3 10.2 1.1e-05 25.9 10.2 1.2 1 7tm_4 Olfactory receptor 9.7e-06 25.8 10.4 1.3e-05 25.4 10.4 1.3 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 0.0033 17.8 12.9 0.0055 17.1 12.9 1.3 1 Git3 G protein-coupled glucose receptor regulating ------ inclusion threshold ------ 5.3 7.8 9.8 0.93 10.2 5.2 2.2 2 GtrA_DPMS_TM GtrA/DPMS, transmembrane domain Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 118.2 9.9 1.3e-37 5.7e-34 1 189 [. 50 237 .. 50 264 .. 0.88 Alignments for each domain: == domain 1 score: 118.2 bits; conditional E-value: 1.3e-37 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvf.....gevlCklvtaldvvnltasillltaisiDRYlaIvkpl 91 gN ++++++ +n+++rt t+++++n+avaDl+++++ +p l ++++++ v+ g++ Cklv++++ v++ +sil+l++isiDR++++ pl FUN_001678-T1 50 GNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVVvggliGTLICKLVGYIQDVSIASSILSLMMISIDRFVVVLFPL 145 8**********************************999999987776665554555559************************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 92 kykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakke 187 k+ + +r +++++ +W++++ ++ p l+ + +++ ++++ Cl ++p + + yt++ +++ + lpl+vi+v+y+ i+ +++++ FUN_001678-T1 146 KNAT--LLKRPRLVVIPIWIISVFMCSPLLYANKIEEY---SGDFYCLEEWPP-HFMTGRDYTVIQFTVLYALPLVVITVLYSCIAVRVWHRTIPG 235 **66..55677889999************997766655...99**********.3459999*****************************998766 PP xx RF 7tm_1 188 ks 189 + FUN_001678-T1 236 HA 237 55 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.3 14.0 1.7e-10 7.2e-07 2 168 .. 45 223 .. 44 257 .. 0.70 Alignments for each domain: == domain 1 score: 29.3 bits; conditional E-value: 1.7e-10 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvll........ltgtqlkreeCFlliivyvfgltaqsvllLvigiDllia 89 +++l GN++++ ++ k++++r+ +++Li+ ++adl++ v++++ ++ + g + C l+ + ++++ + + l++i iD++++ FUN_001678-T1 45 LISLLGNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVqvtnsyavVVGGLIGTLICKLVGYIQDVSIASSILSLMMISIDRFVV 140 799*************************************999876543100000103344456778999999999999999889999******** PP 7TM_GPCR_Srsx 90 vkfPirYrllskek.YllillifpvlyssiilvlgflqrddetiivCa...pplalagkaseiftlssliinvivllvylvli 168 v fP++ +l k++ ++i + + ++ ++ l++ +++ +C pp ++g ++++++++l +v++ l++ FUN_001678-T1 141 VLFPLKNATLLKRPrLVVIPIWIISVFMCSPLLYANKIEEYSGDFYCLeewPPHFMTGRDYTVIQFTVLYALPLVVITVLYSC 223 *************9844444444444444444444444445555777533367777777777766665544433333333333 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 10.2 2.5e-09 1.1e-05 3 144 .. 42 187 .. 40 234 .. 0.77 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 2.5e-09 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlf.....fihkfsllesa.vllamavdr 92 l li+llGn++i+++++ ++ + ++++ +a++dl +++ +P l + + ++ ++ + l+ +i +s+ s +l+ +++dr FUN_001678-T1 42 LAMLISLLGNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVVVGGLIGTLIcklvgYIQDVSIASSIlSLMMISIDR 137 5679************************999*********************999999988765433322222257999999998724556689** PP 7tm_4 93 fvaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevl 144 fv + pl+ +++l +++ +i ++ sv++ pl + + +++ g+ FUN_001678-T1 138 FVVVLFPLKNATLLKRPRLVVIP--IWIISVFMCSPLLYANKIEEYSGDFYC 187 *****************888775..677899999***999999999887544 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 10.4 3e-09 1.3e-05 5 133 .. 45 176 .. 41 256 .. 0.76 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 3e-09 7TM_GPCR_Srx 5 liGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsell.....kellnshliglialglYeisplsqllialNRfca 95 li l+ N++++++++k+ ++++ ++l ++ a+++++i ++ + y + +++++s + + l +l+g+i + s+ls ++i+++Rf++ FUN_001678-T1 45 LISLLGNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVvvgglIGTLICKLVGYIQDVSIASSILSLMMISIDRFVV 140 555677**********************************************999887755544444567778888889999************** PP 7TM_GPCR_Srx 96 vffplkyekifsiknTkiiiviiwivslifitvlylpe 133 v fplk ++ +++ +++++ iwi+s++++ l++ + FUN_001678-T1 141 VLFPLKNATLLKRP--RLVVIPIWIISVFMCSPLLYAN 176 *****999999887..5778999******999544333 PP >> Git3 G protein-coupled glucose receptor regulating Gpa2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 12.9 1.3e-06 0.0055 10 190 .. 42 224 .. 30 232 .. 0.68 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 Git3 10 vassvsivaglvalylllaidkrrrvfRhelillLilvdllkalvlliypvvvlvkksvya......dkafcqvvGfftavaiegaDiaillfalh 99 a +s++ g + ++++ ++r r++ h li+ + + dl+ +++ + y ++v v++s + + +c+ vG++ v+i ++ ++++++ + FUN_001678-T1 42 LAMLISLL-GNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVvvggliGTLICKLVGYIQDVSIASSILSLMMISID 136 34445544.445578888889*****************************998887766541112224579************************* PP Git3 100 tallifkpnlrvkksknvegGLykyRklvyalsvllPlvlasLafinkkegykplstwcYlparpvwyr.....lvLsWvprYii.vvaiiaiyis 189 +++++ p k++ + L + R +v +++++ + + L + nk e y+ +c + p ++ v+ ++ Y++ +v+i ++y + FUN_001678-T1 137 RFVVVLFP---LKNA----TLLKRPRLVVIPIWIISVFMCSPLLYANKIEEYSG-DFYCLE-EWPPHFMtgrdyTVIQFTVLYALpLVVITVLYSC 223 ********...3333....34556788888888888888888888887777753.334432.2222222111224555555665533445555666 PP Git3 190 i 190 i FUN_001678-T1 224 I 224 6 PP >> GtrA_DPMS_TM GtrA/DPMS, transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 5.2 0.00022 0.93 36 106 .. 40 110 .. 29 143 .. 0.80 2 ? -2.0 0.1 1.3 5.6e+03 73 90 .. 208 225 .. 201 241 .. 0.54 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00022 GtrA_DPMS_TM 36 fivailvnfllnrrwtFrdrrskkllkellkfllvslaglllnllllyllv.ellglepllaklvaiivvtv 106 +++a+l++ l+n+ +++ +++++ ++ l+++l+v++a l + ++++ + +++++ +a +v+ +++t+ FUN_001678-T1 40 YVLAMLISLLGNSVIVWIVHKNRR-MRTLTHYLIVNMAVADLMITVFHMPYkLQVQVTNSYAVVVGGLIGTL 110 899*****************9998.*********99887766666655544234444444577776666664 PP == domain 2 score: -2.0 bits; conditional E-value: 1.3 GtrA_DPMS_TM 73 aglllnllllyllvellg 90 + ++l l+++++l++ + FUN_001678-T1 208 VLYALPLVVITVLYSCIA 225 334444444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (275 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 948 (0.037111); expected 510.9 (0.02) Passed bias filter: 410 (0.0160501); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 2856.76 // Query: FUN_001679-T1 [L=424] Description: FUN_001679 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-52 178.5 17.3 3.2e-52 178.1 17.3 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 3.2e-05 24.4 13.5 5.9e-05 23.5 13.5 1.6 1 7tm_4 Olfactory receptor 3.6e-05 23.7 23.0 0.00043 20.2 22.2 2.6 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 3.8e-05 23.7 19.2 6.5e-05 22.9 19.2 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 178.1 17.3 5e-56 3.2e-52 1 260 [] 51 313 .. 51 313 .. 0.93 Alignments for each domain: == domain 1 score: 178.1 bits; conditional E-value: 5e-56 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvf....gevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN++V++v+ rn kl+t+t+++++nLa aDll++++++ + + ++++++d f g+++C ++++ v++ +si++lt+i+++R+++I+ p+k FUN_001679-T1 51 GNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFKTEVVGNDEAFggigGDMYCVGLIVVLNVSVSCSIFNLTVIAVERFCSIMFPFK 146 8****************************************************77777888*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe.eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakke 187 + + t ++a+++++++Wv+++ +++p++++ ++k++ +++ C+ d++ ++ t+++++++++++l + +pll+ilv+y i +l+k++ ++ FUN_001679-T1 147 R--VFTLKLAKAVMVGIWVASFSITIPFFFHIKVKDYYG-DGVFYCVEDWSPlDTVTASQVFQIVFFTLLYACPLLFILVLYLSIGVHLWKRQAQR 239 9..99****************************999855.**********9966777**********************************99988 PP xx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 188 ks....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + ++ ++r + +++k+l++ vv+f+lcwlP +++l+++++ ++ +e ++ +llay+ns++NPiiY FUN_001679-T1 240 EIsslgYSSVRKRMTVQVTKMLVASVVAFALCWLPQHVTLFINYF---MLGRCPPEFLWFGGTLLAYANSAMNPIIY 313 7644553344444445*****************************...999999999******************** PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 13.5 9.2e-09 5.9e-05 3 148 .. 43 188 .. 41 330 .. 0.76 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 9.2e-09 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisf....eacllqlffihkfsllesa.vllamavdrf 93 lv+ i+l+Gn+ +l+v+k ++ lh ++++ la +dl ++ + ++ +v++ e + + + l+ + ++s+ s l +av+rf FUN_001679-T1 43 LVFTISLIGNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFKTEVVGNDEAFGgiggDMYCVGLIVVLNVSVSCSIfNLTVIAVERF 138 7999****************************************999999999999999654111133333333344444444431355689**** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsy 148 +i+ p++ ++t k + ++++v s+ + +p+ f ++ +++g++v y FUN_001679-T1 139 CSIMFPFK--RVFTLKLAKAVMVGIWVASFSITIPFFFHIKVKDYYGDGVF---Y 188 ****9987..5788888899999************************9985...4 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 22.2 6.7e-08 0.00043 7 317 .. 45 329 .. 39 331 .. 0.79 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 6.7e-08 7TM_GPCR_Srw 7 sivgviinifHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgvlmAli 102 +++i nif l++ r ++ ++ l++ a +D+l +++++ + + ++ ++e + + + + l+++ +vs cs++ ++A+ FUN_001679-T1 45 FTISLIGNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFKTEVVG--NDEAFGG--IGGDMYCVGLIVVLNVSVSCSIFNLTVIAVE 136 5689999***********9999999***********************888887..8888776..333344445688899999************* PP 7TM_GPCR_Srw 103 RtlvvknplsnkiqklskpkfglliilivlllsllisilkyfryeiveeeekwkppkeCaefpenysetkyvlvvselftandglllkifllidgi 198 R+ ++++p+++ + + k + +++++ ++s+ i+i ++f+++++++ + C + s l t +++ +i+++ + FUN_001679-T1 137 RFCSIMFPFKRVF----TLKLAKAVMVGIWVASFSITIPFFFHIKVKDYYGDGV--FYCV------------EDWSPLDTVTASQVFQIVFF---T 211 ********98876....699**************************97665433..3464............22333333333444455555...3 PP 7TM_GPCR_Srw 199 lskiipsillpiltilLiieLrkakksrkkls...kskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevifslllt 291 l+ +p + + +l + + L+k + +r+ +s +s +++ + + tk+ + + f + lp+ ++ ++++++ r e l + +ll + FUN_001679-T1 212 LLYACPLLFILVLYLSIGVHLWKRQAQREISSlgySSVRKRMTVQVTKMLVASVVAFALCWLPQHVTLFINYFMLG----RCPPEFLWFGGTLLAY 303 43445555555555555678999988888888887666788999***************************99877....334566667778999* PP 7TM_GPCR_Srw 292 insisHflicllmSsqYRktvkklfg 317 +ns++ +i++++ s+YRk k +++ FUN_001679-T1 304 ANSAMNPIIYVTFHSEYRKQCKLILT 329 *******************9998775 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 19.2 1e-08 6.5e-05 2 254 .. 46 325 .. 45 328 .. 0.75 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1e-08 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv..llltgtql.....kreeCFlliivyvfgltaqsvllLvigiDlliav 90 +++liGN+ +++++ +++kL++ ++ Li+ ++ adll+ + ++ + + + + C li+v +++ + l vi++ +++ + FUN_001679-T1 46 TISLIGNIFVLYVVKRNTKLHTVTHFLIVNLAGADLLITFVNMTVLFktEVVGNDEAfggigGDMYCVGLIVVLNVSVSCSIFNLTVIAVERFCSI 141 799*********************************998766554442133333332111113456888888888888888888999********* PP 7TM_GPCR_Srsx 91 kfPirYrllskekYllillifpvlyssiilvlgflqrdde...tiivCapplalag..kaseiftlssliin.....vivllvylvliiilkkkke 176 +fP++ k +++ i + +s++i ++ +++ d + +C + + +as++f++ + + +++l++yl + + l k+++ FUN_001679-T1 142 MFPFKRVFTLKLAKAVMVGIWVASFSITIPFFFHIKVKDYygdGVFYCVEDWSPLDtvTASQVFQIVFFTLLyacplLFILVLYLSIGVHLWKRQA 237 ***9987777777889999999****9998888888877545589***987765441144566666666555011114455555554444444444 PP 7TM_GPCR_Srsx 177 k...........kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafr 254 + +k+ + +v k l +vv f ++W+ + + + + + e ++ +l+ +++ n +++++ seYrk+ + FUN_001679-T1 238 QreisslgyssvRKRMTVQVTKMLVASVVAFALCWLPQHVTLFINYFMLGRCPPE-FLWFGGTLLAYANSAMNPIIYVTFHSEYRKQCK 325 469********999999*******************9998888887777777766.788888899999999***************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (424 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1214 (0.047524); expected 510.9 (0.02) Passed bias filter: 615 (0.0240752); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4039.01 // Query: FUN_001680-T1 [L=99] Description: FUN_001680 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.41 9.9 1.7 0.43 9.8 1.7 1.0 1 Glypican Glypican 0.66 10.0 6.5 0.68 9.9 6.5 1.1 1 SURF2 Surfeit locus protein 2 (SURF2) 6.9 5.3 9.4 7.4 5.2 9.4 1.0 1 Nop14 Nop14-like family Domain annotation for each model (and alignments): >> Glypican Glypican # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 1.7 5.1e-05 0.43 468 521 .. 23 74 .. 10 96 .. 0.67 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 5.1e-05 Glypican 468 aaaegndvdfqdaeddvsGsgsGegceddkvkkelkiva.satdtpaeeakpaee 521 + a +d+d q ++ddvsGs + e+ +++ v+ ++ ++++++ + +e+ FUN_001680-T1 23 ETAATEDLDTQSEDDDVSGSKDSESEDEPLVEFGDASNSgENDSKDS---ESEEK 74 455689*****************988888877666655533333333...33222 PP >> SURF2 Surfeit locus protein 2 (SURF2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 6.5 7.9e-05 0.68 144 202 .. 28 82 .. 2 94 .. 0.61 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 7.9e-05 SURF2 144 gewepassdeeasdsddsmsDlypdelfteksvgeeededdkesdfetdeeeekakesd 202 + + +s+d+++s s ds+s+ +p +f s+ e+d++d +e++e++e +++++ FUN_001680-T1 28 EDLDTQSEDDDVSGSKDSESEDEPLVEFGDASNSGENDSKD----SESEEKDELPEGAR 82 22233445777777888888888888887666655555544....45666666555544 PP >> Nop14 Nop14-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 9.4 0.00086 7.4 352 408 .. 26 81 .. 3 92 .. 0.36 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.00086 Nop14 352 idddlveseseleeeeeeedeeeeeeeeeee..eeeededdlsdleseeeeedeleeee 408 +dl++++++++ + ++d+e+e+e e +++++ ++++++se+ee+del e++ FUN_001680-T1 26 ATEDLDTQSEDDDV-SGSKDSESEDE-PLVEfgDASNS-GENDSKDSESEEKDELPEGA 81 22222222222222.11111111111.11110111111.11111112555555555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 886 (0.0346839); expected 510.9 (0.02) Passed bias filter: 460 (0.0180074); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1023.62 // Query: FUN_001681-T1 [L=113] Description: FUN_001681 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-10 41.0 0.2 3.7e-10 40.2 0.1 1.4 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.1e-05 25.5 0.1 1.6e-05 25.0 0.1 1.2 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.0085 16.4 0.8 0.01 16.1 0.8 1.1 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.029 15.1 0.1 0.037 14.7 0.1 1.2 1 GtrA_DPMS_TM GtrA/DPMS, transmembrane domain Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 0.52 3.3e+03 108 115 .. 38 45 .. 12 49 .. 0.46 2 ! 40.2 0.1 5.8e-14 3.7e-10 1 43 [. 50 92 .. 50 107 .. 0.91 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 0.52 xxxxxxxx RF 7tm_1 108 vvWvlall 115 +vla+l FUN_001681-T1 38 SLYVLAML 45 12222222 PP == domain 2 score: 40.2 bits; conditional E-value: 5.8e-14 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalv 43 gN ++++++ +n+++rt t+++++n+avaDl+++++ +p l FUN_001681-T1 50 GNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQ 92 8**************************************9875 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 0.1 2.4e-09 1.6e-05 2 49 .. 45 92 .. 44 101 .. 0.91 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 2.4e-09 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvl 49 +++l GN++++ ++ k++++r+ +++Li+ ++adl++ v++++ ++ FUN_001681-T1 45 LISLLGNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQ 92 799***************************************987655 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.8 1.6e-06 0.01 3 52 .. 42 91 .. 40 103 .. 0.90 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 1.6e-06 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvl 52 l li+llGn++i+++++ ++ + ++++ +a++dl +++ +P l FUN_001681-T1 42 LAMLISLLGNSVIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKL 91 5679***********************999999*********99999776 PP >> GtrA_DPMS_TM GtrA/DPMS, transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.1 5.8e-06 0.037 36 79 .. 40 82 .. 27 105 .. 0.72 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 5.8e-06 GtrA_DPMS_TM 36 fivailvnfllnrrwtFrdrrskkllkellkfllvslaglllnl 79 +++a+l++ l+n+ +++ +++++ ++ l+++l+v++a l + FUN_001681-T1 40 YVLAMLISLLGNSVIVWIVHKNRR-MRTLTHYLIVNMAVADLMI 82 678888888888888888888876.8888888888776554444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 953 (0.0373067); expected 510.9 (0.02) Passed bias filter: 514 (0.0201214); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.35s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1170.94 // Query: FUN_001682-T1 [L=401] Description: FUN_001682 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-49 167.3 16.9 8.8e-49 166.8 16.9 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 2.6e-13 50.4 12.4 6.5e-13 49.1 12.4 1.6 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 3.8e-05 23.9 10.7 3.8e-05 23.9 10.7 1.8 2 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 0.00027 21.3 13.4 0.00048 20.5 13.1 1.7 1 7tm_4 Olfactory receptor 0.0016 18.8 17.9 0.0042 17.5 14.3 2.3 2 Git3 G protein-coupled glucose receptor regulating Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 166.8 16.9 1.7e-52 8.8e-49 1 260 [] 50 313 .. 50 313 .. 0.89 Alignments for each domain: == domain 1 score: 166.8 bits; conditional E-value: 1.7e-52 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvf.....gevlCklvtaldvvnltasillltaisiDRYlaIvkpl 91 gN +++++ +n+++rt t+++++n+avaDl+++++ +p l ++++++ v+ g++ Cklv++++ v++ +sil+l++isiDR++++ pl FUN_001682-T1 50 GNSAIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVVvggliGTLICKLVGYIQDVSIASSILSLMMISIDRFVVVLFPL 145 8**********************************999999987776665554555559************************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 92 kykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakke 187 k+ + +r +++++ +W++++ ++ p l+ + +++ ++++ C+ ++p + + yt++ +++ + lpl+vi+ +y+ i+ +++++ FUN_001682-T1 146 KNAT--LLKRPRLVVIPIWIISVFMCSPLLYANKIEEY---SGDFYCFEEWPP-HFMTGRDYTVIQFTVLYALPLVVITALYSCIAVRVWHRTIPG 235 **66..55677889999************997766655...99**********.3459999*********************************** PP xx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 188 ks.....kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 + + +++ +++++lk+l+++v +f++cwlPy+++++l+ + ++ ++et++ ++l+++++ns++NP iY FUN_001682-T1 236 HAapnltRGRRHLGARKQLLKLLIIIVSLFAICWLPYHVIFFLQFSESGYLNCGVPETIMFYCLFMGHANSAINPCIY 313 99666653333333444***************************99888889999*********************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.1 12.4 1.3e-16 6.5e-13 2 253 .. 45 324 .. 44 328 .. 0.78 Alignments for each domain: == domain 1 score: 49.1 bits; conditional E-value: 1.3e-16 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvll........ltgtqlkreeCFlliivyvfgltaqsvllLvigiDllia 89 +++l GN+ ++ ++ k++++r+ +++Li+ ++adl++ v++++ ++ + g + C l+ + ++++ + + l++i iD++++ FUN_001682-T1 45 LISLLGNSAIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVqvtnsyavVVGGLIGTLICKLVGYIQDVSIASSILSLMMISIDRFVV 140 799*************************************999876543100000103344456778999999999999999889999******** PP 7TM_GPCR_Srsx 90 vkfPirYrllskek...YllillifpvlyssiilvlgflqrddetiivCa...pplalagkaseiftlssliinvivllvylvliiilkkkkek.. 177 v fP++ +l k++ + i +i ++++s ++ + +++ +C pp ++g ++++++++l +v++ l++ i ++ + + FUN_001682-T1 141 VLFPLKNATLLKRPrlvVIPIWIISVFMCSPLL--YANKIEEYSGDFYCFeewPPHFMTGRDYTVIQFTVLYALPLVVITALYSCIAVRVWHRTip 234 *************98433334444444555444..4444444455567743337888888888888888777776777766777777777777688 PP 7TM_GPCR_Srsx 178 ............kkssskkvlkslkvtvvififgWftstilntvllalte..seevekliqayagilvllsfsqnffVtywrsseYrkaf 253 + k++lk l + v++f ++W+ +++ + + + + v + i+ y+ ++ +++ n ++ ++ +eYrk + FUN_001682-T1 235 ghaapnltrgrrHLGARKQLLKLLIIIVSLFAICWLPYHVIFFLQFSESGylNCGVPETIMFYCLFMGHANSAINPCIYFIIHNEYRKGL 324 99999999998888899******************99888877766554411667889*****************************975 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 10.7 7.3e-09 3.8e-05 5 147 .. 45 189 .. 41 248 .. 0.72 2 ? -1.7 1.2 0.48 2.4e+03 127 168 .. 260 300 .. 252 326 .. 0.44 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 7.3e-09 7TM_GPCR_Srx 5 liGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsell.....kellnshliglialglYeisplsqllialNRfca 95 li l+ N+ ++++++k+ ++++ ++l ++ a+++++i ++ + y + +++++s + + l +l+g+i + s+ls ++i+++Rf++ FUN_001682-T1 45 LISLLGNSAIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVvvgglIGTLICKLVGYIQDVSIASSILSLMMISIDRFVV 140 555677**********************************************999887755544444567778888889999************** PP 7TM_GPCR_Srx 96 vffplkyekifsiknTkiiiviiwivslifitvlylpegCkllynpetltws 147 v fplk ++ +++ +++++ iwi+s++++ l++ ++ y+ +++ ++ FUN_001682-T1 141 VLFPLKNATLLKRP--RLVVIPIWIISVFMCSPLLYANK-IEEYSGDFYCFE 189 *****999999887..5778999******9995554432.334555555543 PP == domain 2 score: -1.7 bits; conditional E-value: 0.48 7TM_GPCR_Srx 127 tvlylpegCkllynpetltwsfee.teccktiswyldfllili 168 +++ l+ C+l y+ ++ + e+ c +++ ++ +l+ FUN_001682-T1 260 IIVSLFAICWLPYHVIFFLQFSESgYLNCGVPETI--MFYCLF 300 33333444555555443332222212222222222..233333 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 13.1 9.3e-08 0.00048 3 141 .. 42 184 .. 40 327 .. 0.85 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 9.3e-08 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlf.....fihkfsllesa.vllamavdr 92 l li+llGn+ i+++++ ++ + ++++ +a++dl +++ +P l + + ++ ++ + l+ +i +s+ s +l+ +++dr FUN_001682-T1 42 LAMLISLLGNSAIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVVVGGLIGTLIcklvgYIQDVSIASSIlSLMMISIDR 137 5679************************9999********************999999988765433322222257999999998724556689** PP 7tm_4 93 fvaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgs 141 fv + pl+ +++l +++ +i ++ sv++ pl + + +++ g+ FUN_001682-T1 138 FVVVLFPLKNATLLKRPRLVVIP--IWIISVFMCSPLLYANKIEEYSGD 184 *****************988775..677899999999999998888876 PP >> Git3 G protein-coupled glucose receptor regulating Gpa2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 14.3 8.2e-07 0.0042 10 194 .. 42 228 .. 31 233 .. 0.76 2 ? 2.4 0.1 0.033 1.7e+02 32 65 .. 246 279 .. 239 322 .. 0.79 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 8.2e-07 Git3 10 vassvsivaglvalylllaidkrrrvfRhelillLilvdllkalvlliypvvvlvkksvya......dkafcqvvGfftavaiegaDiaillfalh 99 a +s+ +g a+ ++++ ++r r++ h li+ + + dl+ +++ + y ++v v++s + + +c+ vG++ v+i ++ ++++++ + FUN_001682-T1 42 LAMLISL-LGNSAIVWIVHKNRRMRTLTHYLIVNMAVADLMITVFHMPYKLQVQVTNSYAVvvggliGTLICKLVGYIQDVSIASSILSLMMISID 136 4444554.47789*************************************999887766541112224579************************* PP Git3 100 tallifkpnlrvkksknvegGLykyRklvyalsvllPlvlasLafinkkegykplstwcYlparpvwyr....lvLsWvprYii.vvaiiaiyisi 190 +++++ p k+ + L + R +v +++++ + + L + nk e y+ +c+ p ++ v+ ++ Y++ +v+i a+y +i FUN_001682-T1 137 RFVVVLFP---LKN----ATLLKRPRLVVIPIWIISVFMCSPLLYANKIEEYSG-DFYCFEEWPPHFMTgrdyTVIQFTVLYALpLVVITALYSCI 224 ********...333....344667899999999999999999999998888864.66787655554432223367778888877456777888888 PP Git3 191 yiyv 194 + v FUN_001682-T1 225 AVRV 228 7666 PP == domain 2 score: 2.4 bits; conditional E-value: 0.033 Git3 32 rrrvfRhelillLilvdllkalvlliypvvvlvk 65 r+ R++l+ lLi++ l a++ l y v+ + + FUN_001682-T1 246 RHLGARKQLLKLLIIIVSLFAICWLPYHVIFFLQ 279 55567999**999999999999999999887764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (401 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1244 (0.0486984); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3909.38 // Query: FUN_001683-T1 [L=310] Description: FUN_001683 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-35 122.3 0.0 4.3e-35 122.0 0.0 1.0 1 PfkB pfkB family carbohydrate kinase Domain annotation for each model (and alignments): >> PfkB pfkB family carbohydrate kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 122.0 0.0 1.7e-39 4.3e-35 2 294 .. 4 294 .. 3 298 .. 0.89 Alignments for each domain: == domain 1 score: 122.0 bits; conditional E-value: 1.7e-39 PfkB 2 tkvvviGeanidlianeekl..egelvevstvektaGGkgaNvAvalarlgakvaflgavGdDnfgefllqelkkegvdtsyvkidedtrtglali 95 +kv+++G++ d++ + e+ e+e +++ + + + GG+++ A+++ +lg++ flg + + +ef+ ++l+++g++++++++ d+ t + ++ FUN_001683-T1 4 KKVLCVGLIALDIVSTCERYpnEDEDMRATSQRWQTGGNACTNATVMTQLGIECEFLGSLSEGTEAEFVCKHLRDRGIEHEHCVRHSDCGTPTSVV 99 799******************99*****************************************************************99999999 PP PfkB 96 evded.gertivfnrgaaadltkeeleenedlleeadllyisgllskelpeaaleelaeaaknagt...fdpvlldplgssakeallellpladll 187 +++ + g rt++ r++ +++ +++ ++ +l++ ++++g ++++ +a + +++++ +d ++++ ++ ++ l ll +ad+l FUN_001683-T1 100 TLSLAtGSRTVLHARNNLPEMNLSAF--QKVNLANYYWIHFEG---RRNESEIVKMIAIVDEFNSKrtaHDKIVVSVELEKPRQSLVPLLDKADVL 190 9998889*********9999999887..77788899999****...666677777777777777777779999999999999************** PP PfkB 188 kpNeeElealtgakledieealkalhkllakgaktvvvtlGaeGalvvekdgevkvpav.pkvkvvDttGAGDsfvggflaallegksleeavrfa 282 +++++ + +++g ++ e +++ + k +++g +tv+ G+eGa + dgevk++ + +++v+Dt GAGD+fv+g +++l ++ s+e+ + fa FUN_001683-T1 191 FTSKDFA-RFCGYS-KASEAVKAFYSK-VKAG-ATVICAWGDEGADGIGPDGEVKHSDAyCPKEVIDTLGAGDTFVAGAIYSLIKQSSIEDTLNFA 282 *997655.577777.256566666666.4445.7**********************99986799******************************** PP PfkB 283 naaAalvvqkkg 294 +++A l + +g FUN_001683-T1 283 CKLAGLKCGMRG 294 *****9987666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (310 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 688 (0.0269329); expected 510.9 (0.02) Passed bias filter: 606 (0.0237228); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 3165.10 // Query: FUN_001684-T1 [L=73] Description: FUN_001684 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.27 11.7 0.0 0.32 11.4 0.0 1.1 1 Adenyl_cycl_N Adenylate cyclase NT domain Domain annotation for each model (and alignments): >> Adenyl_cycl_N Adenylate cyclase NT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 1.2e-05 0.32 110 137 .. 16 43 .. 6 49 .. 0.89 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 1.2e-05 Adenyl_cycl_N 110 SDlDiWvchrselsaeeleeLekKleli 137 DlD+W+ +++l+ae+ L++Kl+++ FUN_001684-T1 16 HDLDTWIPGSESLKAERSIMLKRKLNSV 43 6***********************9987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (73 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 252 (0.00986494); expected 510.9 (0.02) Passed bias filter: 230 (0.00900372); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 757.98 // Query: FUN_001685-T1 [L=436] Description: FUN_001685 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-51 176.3 19.7 1.4e-51 176.0 19.7 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 8.6e-06 25.8 17.1 1.6e-05 24.9 17.1 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.14 12.4 14.6 0.47 10.7 14.6 1.9 1 7tm_4 Olfactory receptor Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.0 19.7 1.6e-55 1.4e-51 1 260 [] 72 335 .. 72 335 .. 0.91 Alignments for each domain: == domain 1 score: 176.0 bits; conditional E-value: 1.6e-55 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvf...gevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+lVi+v rn++lrt ++ f++n+a+aDl+++++++p +++ ++ +++w g v+Ck+ +l+ v+ ++s+l+l+ais+DRY aI+ p+k FUN_001685-T1 72 GNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESVIVEIrDTDQWFPgkvGVVMCKFGPFLQQVCAFCSVLSLLAISLDRYFAICLPFK 167 8*****************************************9999334555444447789*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakk 186 + i+++++ +vlil++W+l ++ s p+++ ++ + ++e Cl +p+ + +++ yt++l+vl+++ pl+vi+++y++++ ++++++ FUN_001685-T1 168 R--IMSQKLSRVLILLTWLLPVVSSAPMFVANNVVEI---SGELLCLEAWPSpfDPVKAHTDYTIILFVLFYVFPLTVISFLYSLVIFKIWRRRVP 258 9..***************************8888777...89**********65555599**********************************99 PP xxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 187 eks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ + + +r++rkalk+ + +vv f+lcwlPy+++++l+s+++ ++ l++ + i+++++y+ s++NP iY FUN_001685-T1 259 GNRstvTTEAYSRSRRKALKVFISIVVCFALCWLPYHVTFFLSSYNEIYFNCGLPRDIAFIAVFFSYAISAFNPCIY 335 9985553333345566*****************************88889999999999****************** PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 17.1 1.9e-09 1.6e-05 2 256 .. 67 349 .. 66 350 .. 0.68 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 1.9e-09 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvv.llltgtq..lkre....eCFlliivyvfgltaqsvllLvigiDlliav 90 + +l+GN+l+i + ++++Lr+ + ++ ++adl+ v ++++ v + +++t + + C + ++ + ++ + + lL+i +D+ +a+ FUN_001685-T1 67 IASLVGNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESViVEIRDTDqwFPGKvgvvMCKFGPFLQQVCAFCSVLSLLAISLDRYFAI 162 6689************************************9999887355655431123331111455555555555555666699********** PP 7TM_GPCR_Srsx 91 kfPirYrllskek..Yllillifpvlyssiil.vlgflqrddetiivCapplalag.kas.eiftlssliinvi..vllvylvliiilkkkkek.. 177 +P++ +k +l++ ++pv+ s+ ++ + ++++++ e + a p +++ ka ++ ++ ++++v+ +++ +l++ +i+k + + FUN_001685-T1 163 CLPFKRIMSQKLSrvLILLTWLLPVVSSAPMFvANNVVEISGELLCLEAWPSPFDPvKAHtDYTIILFVLFYVFplTVISFLYSLVIFKIWRRRvp 258 ***865444433367777777788877775550556677777766555666666541222222223333334331144444444555555555566 PP 7TM_GPCR_Srsx 178 ..........kkssskkvlkslkvtvvififgWftstilntvlla..lteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 ++s +k lk vv f ++W+ + + ++ + + ++ + + i a+++ +++n ++++ ++eYr+ ++l FUN_001685-T1 259 gnrstvtteaYSRSRRKALKVFISIVVCFALCWLPYHVTFFLSSYneIYFNCGLPRDIAFIAVFFSYAISAFNPCIYLILNKEYRTGSKRL 349 8888888777677777888888888888899**988877777665226777888888999999999999999999**********977665 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 14.6 5.5e-05 0.47 3 277 .. 64 350 .. 61 353 .. 0.65 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 5.5e-05 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdare.....isfeacllqlffihkfsllesavllamavdrf 93 ++ + +l+Gn+ ++ v + ++ l y f+ +a++dl ++ +P+ + + + d+ + + c + f+ ++ +lla+++dr+ FUN_001685-T1 64 VIIIASLVGNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESVIVEIRDTDQwfpgkVGVVMCKFGPFLQQVCAFCSVLSLLAISLDRY 159 4567789****************************************987665555543111114556788888877788899999********** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvilv.lplifllrrlkfcgsevlshs.yclhaelaklscadikvnniyGlfvvvstlgldsllivls 187 ai+ p++ i+++k l r +il+ l+++ f++++v+ s +l e + +k+ + y +++ v +++ +i + FUN_001685-T1 160 FAICLPFK--RIMSQK---------LSRVLILLtWLLPVVSSAPMFVANNVVEISgELLCLEAWPSPFDPVKAHTDYTIILFVLFYVFPLTVISFL 244 ****8876..577777.........22333333033566677778899999988753445555666777788888888877777788888888888 PP 7tm_4 188 yglil.....r.......tvlgiasreerkkalntcgshvcavlafyvPmiglsvvhr.....fgkkvsrllqvllanlyllfPPvlnPivysvkt 266 y+l++ r tv + a +r+kal+ s v+ + + P + + f ++r + ++a + + +nP +y + FUN_001685-T1 245 YSLVIfkiwrRrvpgnrsTVTTEAYSRSRRKALKVFISIVVCFALCWLPYHVTFFLSSyneiyFNCGLPRDIA-FIAVFFSYAISAFNPCIYLILN 339 8887622222112222223444444567899999988877666555555544444444000113333444443.2333333334567888888888 PP 7tm_4 267 keirdavvkil 277 ke r +++l FUN_001685-T1 340 KEYRTGSKRLL 350 88877666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (436 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 923 (0.0361323); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4270.67 // Query: FUN_001686-T1 [L=126] Description: FUN_001686 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.016 15.4 1.5 0.025 14.9 1.5 1.3 1 KIF21A KIF21A-like domain 0.19 12.9 1.4 0.38 11.9 1.4 1.6 1 SMAP Small acidic protein family 0.23 12.6 2.4 0.23 12.6 0.9 1.9 2 SlyX SlyX 0.31 11.7 3.9 2.5 8.8 0.4 2.8 3 TolA_bind_tri TolA binding protein trimerisation 1.1 9.7 8.9 1.9 8.9 2.7 2.0 2 Ax_dynein_light Axonemal dynein light chain 1.5 9.7 8.4 2.9 8.8 8.4 1.6 1 DUF4200 Domain of unknown function (DUF4200) 2.2 8.6 6.9 0.36 11.1 0.8 2.3 2 DivIC Septum formation initiator Domain annotation for each model (and alignments): >> KIF21A KIF21A-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 1.5 6.8e-06 0.025 15 95 .. 44 122 .. 30 124 .. 0.62 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 6.8e-06 KIF21A 15 errisdivl..qrqtia.nlEkdmerlLkeReklsrkleklerkrerleaeskedekalqeldeeieslkanidyiqdsIsecQ 95 er++s+++l +rqt++ nlE++ ++ L++R+ +++++ ++ ++ ++++k++ +l+ +i l+++i +q +++e+Q FUN_001686-T1 44 ERAVSNQALkkKRQTLHgNLETQYDETLTKRHI-EKEKQATSIANN----PLPKADKEVLRLQGKILRLQEKIAKLQHKVAELQ 122 566666665114566644778888877777763.332333322222....2345556667777777777777777777777776 PP >> SMAP Small acidic protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 1.4 0.0001 0.38 35 66 .. 44 75 .. 15 83 .. 0.71 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0001 SMAP 35 sakanmalskkkqeklqqdLekQyeaamkkke 66 +++ + ++ kkk+++l +Le Qy++ + k++ FUN_001686-T1 44 ERAVSNQALKKKRQTLHGNLETQYDETLTKRH 75 255666778999**************999433 PP >> SlyX SlyX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 1.3 4.9e+03 50 50 .. 66 66 .. 47 91 .. 0.55 2 ? 12.6 0.9 6.4e-05 0.23 23 52 .. 94 123 .. 83 126 .] 0.90 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 1.3 SlyX 50 l 50 FUN_001686-T1 66 Q 66 1 PP == domain 2 score: 12.6 bits; conditional E-value: 6.4e-05 SlyX 23 ndvvaeqqreidrlqrqlrllaerlkelee 52 +++v + q +i rlq+++++l+ +++el+ FUN_001686-T1 94 DKEVLRLQGKILRLQEKIAKLQHKVAELQG 123 57899********************99985 PP >> TolA_bind_tri TolA binding protein trimerisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.1 0.16 5.7e+02 28 45 .. 50 67 .. 46 74 .. 0.83 2 ? 6.3 0.3 0.0041 15 13 52 .. 76 115 .. 71 115 .. 0.83 3 ? 8.8 0.4 0.00067 2.5 19 40 .. 103 124 .. 101 125 .. 0.90 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.16 TolA_bind_tri 28 eqLqqevaeLRGqiEelq 45 ++L++ + L+G +E + FUN_001686-T1 50 QALKKKRQTLHGNLETQY 67 678999999999999885 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0041 TolA_bind_tri 13 learnqallelqqqleqLqqevaeLRGqiEelqyqleqlq 52 +e+ +qa + + l + +ev +L+G+i +lq ++ +lq FUN_001686-T1 76 IEKEKQATSIANNPLPKADKEVLRLQGKILRLQEKIAKLQ 115 66667888888888999999*********99999998876 PP == domain 3 score: 8.8 bits; conditional E-value: 0.00067 TolA_bind_tri 19 allelqqqleqLqqevaeLRGq 40 ++l+lq+++ +Lq+ vaeL+G FUN_001686-T1 103 KILRLQEKIAKLQHKVAELQGL 124 5789*****************6 PP >> Ax_dynein_light Axonemal dynein light chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 2.7 0.00053 1.9 108 172 .. 18 86 .. 13 90 .. 0.84 2 ? 4.7 0.4 0.01 37 117 146 .. 93 122 .. 87 125 .. 0.77 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00053 Ax_dynein_light 108 aFgvrkalqaeqgkaelekkikeLeee....keeLekevaelkakleelekreeeerqeeekkhaeeia 172 +gvr +++ eq ++e+ +++++++ e +++L+k+ ++l+ +le+ + ++r++e++k+a+ ia FUN_001686-T1 18 SHGVRGQTNYEQSSKETPNNVHDVKPEravsNQALKKKRQTLHGNLETQYDETLTKRHIEKEKQATSIA 86 69*********************9866233368899999999999999999999999999999887775 PP == domain 2 score: 4.7 bits; conditional E-value: 0.01 Ax_dynein_light 117 aeqgkaelekkikeLeeekeeLekevaelk 146 a+++ +l+ ki +L+e+ ++L+++vael+ FUN_001686-T1 93 ADKEVLRLQGKILRLQEKIAKLQHKVAELQ 122 556666778888888888888888888876 PP >> DUF4200 Domain of unknown function (DUF4200) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 8.4 0.00078 2.9 33 107 .. 49 122 .. 24 124 .. 0.80 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00078 DUF4200 33 eeelekkeqelkedl.vkfdkflkeneakreraekkaeeetkekkekekeikklkaeleelkseiskleekleeyk 107 ++l+kk+q l +l +++d+ l + ++e+ +++ + +ke+ +l+ ++ +l+++i+kl+ k++e++ FUN_001686-T1 49 NQALKKKRQTLHGNLeTQYDETLTKRHIEKEKQATSIANNPL--PKADKEVLRLQGKILRLQEKIAKLQHKVAELQ 122 578999999999999789999988777666665555554444..45577899********************9987 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.7 0.18 6.7e+02 27 38 .. 46 57 .. 16 82 .. 0.67 2 ? 11.1 0.8 9.9e-05 0.36 23 51 .. 94 122 .. 90 125 .. 0.85 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.18 DivIC 27 aeleaeiaklka 38 a +++++k+++ FUN_001686-T1 46 AVSNQALKKKRQ 57 444444444443 PP == domain 2 score: 11.1 bits; conditional E-value: 9.9e-05 DivIC 23 kqeiaeleaeiaklkaeneeLeaeikdLk 51 ++e+ +l+ +i +l++++++L++++++L+ FUN_001686-T1 94 DKEVLRLQGKILRLQEKIAKLQHKVAELQ 122 68899999999999999999999999983 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2015 (0.0788804); expected 510.9 (0.02) Passed bias filter: 816 (0.0319436); expected 510.9 (0.02) Passed Vit filter: 93 (0.00364063); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1253.14 // Query: FUN_001687-T1 [L=1059] Description: FUN_001687 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00043 20.8 6.8 14 6.3 0.4 5.8 6 Type_III_YscG Bacterial type III secretion system chaperone 0.00061 20.4 0.0 8.6 7.1 0.0 3.8 4 GLGE_C GLGE, C-terminal ------ inclusion threshold ------ 1 8.9 6.9 1.9 8.0 2.0 2.7 2 Loricrin Major keratinocyte cell envelope protein 1.1 10.1 7.8 23 5.9 0.1 4.6 5 OMP10 Outer membrane lipoprotein Omp10 Domain annotation for each model (and alignments): >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.3 0.4 0.0022 14 11 45 .. 235 269 .. 227 281 .. 0.66 2 ! 4.5 0.1 0.0079 50 14 38 .. 256 280 .. 252 296 .. 0.82 3 ? 2.4 0.1 0.035 2.2e+02 11 35 .. 307 331 .. 281 336 .. 0.67 4 ? 2.8 0.1 0.026 1.7e+02 11 38 .. 307 334 .. 299 351 .. 0.80 5 ! 4.4 0.0 0.0086 55 11 37 .. 361 387 .. 354 404 .. 0.81 6 ? 3.0 0.0 0.023 1.5e+02 11 38 .. 415 442 .. 406 464 .. 0.79 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0022 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgeeeaarlir 45 + l+ G h +ean+i+ l +g+ + FUN_001687-T1 235 SLDLIADGTHTGNEANCISSGLIGNGNSAGNEANC 269 57788889999999999988887777664333333 PP == domain 2 score: 4.5 bits; conditional E-value: 0.0079 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkgee 38 l+G G+ +ean+i+ l +g++ FUN_001687-T1 256 LIGNGNSAGNEANCISSDLIANGNH 280 9**************9988877665 PP == domain 3 score: 2.4 bits; conditional E-value: 0.035 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerk 35 + l+ G+ +ean+i+ l + FUN_001687-T1 307 SLDLIADGNSTGNEANCISSDLIAN 331 4556777777777777776655554 PP == domain 4 score: 2.8 bits; conditional E-value: 0.026 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgee 38 + l+ G+ +ean+i+ l +g++ FUN_001687-T1 307 SLDLIADGNSTGNEANCISSDLIANGNH 334 5789999***********9888777664 PP == domain 5 score: 4.4 bits; conditional E-value: 0.0086 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkge 37 + l+ G+ +ean+i+ +l ++ + FUN_001687-T1 361 SLDLIADGNSTGNEANCISSYLISNRN 387 57899****************987654 PP == domain 6 score: 3.0 bits; conditional E-value: 0.023 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgee 38 + l+ G+ +ean+i+ l ++g+ FUN_001687-T1 415 SLDLIADGNSTGNEANCISSDLISNGNY 442 5789999***********9998887764 PP >> GLGE_C GLGE, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.7 0.0 0.0018 11 51 79 .. 212 240 .. 203 245 .. 0.80 2 ? -2.4 0.0 1.2 7.9e+03 31 76 .. 298 345 .. 292 348 .. 0.75 3 ? 1.2 0.0 0.098 6.3e+02 31 76 .. 352 399 .. 346 403 .. 0.77 4 ! 7.1 0.0 0.0013 8.6 31 76 .. 406 453 .. 400 456 .. 0.81 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0018 GLGE_C 51 eesfevhDlltgeeyeWgeenyVrLdpek 79 e+ + +Dl+t +y+ +e+nyV+Ld + FUN_001687-T1 212 EADCVSQDLITSGNYTGNEANYVSLDLIA 240 4567789******************9665 PP == domain 2 score: -2.4 bits; conditional E-value: 1.2 GLGE_C 31 phntqegtveldlealgleeee..sfevhDlltgeeyeWgeenyVrLd 76 p+ +++ ++ldl a g ++++ ++ +Dl+ + +++ +e+ny +Ld FUN_001687-T1 298 PTGNEANCISLDLIADGNSTGNeaNCISSDLIANGNHNGNEANYESLD 345 666777788999988887765411567789999999999999987776 PP == domain 3 score: 1.2 bits; conditional E-value: 0.098 GLGE_C 31 phntqegtveldlealgleeee..sfevhDlltgeeyeWgeenyVrLd 76 p+ +++ ++ldl a g ++++ ++ + l+++++y+ +e n+V+Ld FUN_001687-T1 352 PTGNEANCISLDLIADGNSTGNeaNCISSYLISNRNYTGNEVNFVSLD 399 6666777788888888877654114556779***************98 PP == domain 4 score: 7.1 bits; conditional E-value: 0.0013 GLGE_C 31 phntqegtveldlealgleeee..sfevhDlltgeeyeWgeenyVrLd 76 p+ +++ ++ldl a g ++++ ++ +Dl+++ +y+ +e nyV+Ld FUN_001687-T1 406 PTGNEANCISLDLIADGNSTGNeaNCISSDLISNGNYTGNEVNYVSLD 453 66777788999999988876541167789*****************98 PP >> Loricrin Major keratinocyte cell envelope protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 2.0 0.0003 1.9 107 180 .. 245 327 .. 223 343 .. 0.71 2 ? 2.2 0.3 0.018 1.2e+02 118 179 .. 367 434 .. 347 465 .. 0.51 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0003 Loricrin 107 ggggsgcfssg...gggssgggsgcfssg..gggssgggsgcfss....ggggfsgqavqcqsyggvssggssgggsgcfssg 180 g + c+ssg g s+g + c+ss + g+ g + + s + g +g+ +c s ++ g s+g + c+ss FUN_001687-T1 245 TGNEANCISSGligNGNSAGNEANCISSDliANGNHNGNEANYESldliAIGNPTGNEANCISLDLIADGNSTGNEANCISSD 327 35556677775442455667777888885334566666666666523334577889999999999999999999999999885 PP == domain 2 score: 2.2 bits; conditional E-value: 0.018 Loricrin 118 gggssgggsgcfssg..gggssgggsgcfss....ggggfsgqavqcqsyggvssggssgggsgcfss 179 g s+g + c+ss + g f s + g +g+ +c s ++ g s+g + c+ss FUN_001687-T1 367 DGNSTGNEANCISSYliSNRNYTGNEVNFVSldliAIGNPTGNEANCISLDLIADGNSTGNEANCISS 434 34444444445444311122222333333331111234445555556666666666666666666555 PP >> OMP10 Outer membrane lipoprotein Omp10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.1 0.0035 23 27 62 .. 217 252 .. 208 256 .. 0.88 2 ? 0.9 0.1 0.13 8.1e+02 16 61 .. 276 323 .. 259 328 .. 0.61 3 ? 0.9 0.2 0.13 8.1e+02 16 61 .. 330 377 .. 313 395 .. 0.66 4 ? -1.5 0.0 0.7 4.5e+03 31 62 .. 383 414 .. 366 418 .. 0.84 5 ? 2.5 0.2 0.041 2.6e+02 27 60 .. 433 466 .. 409 468 .. 0.80 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0035 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskvnCa 62 +++ +++G+Yt ++a+ v+++l ++t ++nC FUN_001687-T1 217 SQDLITSGNYTGNEANYVSLDLIADGTHTGNEANCI 252 566889*****************************5 PP == domain 2 score: 0.9 bits; conditional E-value: 0.13 OMP10 16 snGrFetratd..tgekLaeGtYtktsaklveieltslvrktqskvnC 61 +nG+ + ++++ + + +a G+ t ++a+ ++++l + t ++nC FUN_001687-T1 276 ANGNHNGNEANyeSLDLIAIGNPTGNEANCISLDLIADGNSTGNEANC 323 455555554442233456666666666666777766666666666666 PP == domain 3 score: 0.9 bits; conditional E-value: 0.13 OMP10 16 snGrFetratd..tgekLaeGtYtktsaklveieltslvrktqskvnC 61 +nG+ + ++++ + + +a G+ t ++a+ ++++l + t ++nC FUN_001687-T1 330 ANGNHNGNEANyeSLDLIAIGNPTGNEANCISLDLIADGNSTGNEANC 377 455555555442233466667777777777777777777777777776 PP == domain 4 score: -1.5 bits; conditional E-value: 0.7 OMP10 31 LaeGtYtktsaklveieltslvrktqskvnCa 62 +++ +Yt ++ + v+++l + + t ++nC FUN_001687-T1 383 ISNRNYTGNEVNFVSLDLIAIGNPTGNEANCI 414 56678999999999999999999999999995 PP == domain 5 score: 2.5 bits; conditional E-value: 0.041 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskvn 60 + + +++G+Yt ++ + v+++l + ++t ++n FUN_001687-T1 433 SSDLISNGNYTGNEVNYVSLDLIAIGNQTGNEAN 466 567899****************999999887776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1059 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1678 (0.065688); expected 510.9 (0.02) Passed bias filter: 548 (0.0214523); expected 510.9 (0.02) Passed Vit filter: 74 (0.00289685); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.50u 0.36s 00:00:00.86 Elapsed: 00:00:00.41 # Mc/sec: 10470.85 // Query: FUN_001688-T1 [L=120] Description: FUN_001688 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-12 45.7 0.1 2.5e-07 31.4 0.0 2.1 2 EF-hand_7 EF-hand domain pair 1.5e-07 31.0 0.1 0.00043 20.3 0.0 4.1 4 EF-hand_6 EF-hand domain 4.6e-06 26.3 0.3 0.055 13.5 0.0 4.4 5 EF-hand_1 EF hand domain 9.8e-05 22.5 0.3 0.42 10.9 0.0 3.3 3 EF-hand_8 EF-hand domain pair 0.00014 22.3 0.0 0.00023 21.6 0.0 1.5 1 EF-hand_SWAP70_N Switch-associated protein 70-like, N-termin ------ inclusion threshold ------ 0.015 16.7 0.0 0.024 16.0 0.0 1.4 1 EF-hand_11 EF-hand domain 0.081 13.7 0.3 12 6.6 0.0 2.0 2 AIF-1 Allograft inflammatory factor 1 Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.0 4.8e-05 0.17 19 66 .. 2 44 .. 1 45 [. 0.81 2 ! 31.4 0.0 6.7e-11 2.5e-07 1 66 [. 55 118 .. 55 119 .. 0.95 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4.8e-05 EF-hand_7 19 ldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 ++++el l+ + ++ge+++ e+eel+ + + ++sf EFl+++ FUN_001688-T1 2 VTEKELG-LIMR-SLGENITNFEIEELMTK---AGKQKVSFPEFLKMV 44 5778888.5555.99999999999999555...88889*******996 PP == domain 2 score: 31.4 bits; conditional E-value: 6.7e-11 EF-hand_7 1 eeklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 e+++ aF +lD++++G++++++l++l++ ++g++l ee++++++++ l + +i ++++++++ FUN_001688-T1 55 EKEILAAFTALDREKTGSVSRSQLQHLMT--GTGDKLGSEEFDHMLRDLGLEGCASIQYTDLVRAI 118 578999***********************..******************************99886 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.061 2.2e+02 17 30 .] 2 15 .. 1 15 [. 0.91 2 ? 0.0 0.0 0.39 1.4e+03 13 26 .. 31 44 .. 25 49 .. 0.82 3 ! 20.3 0.0 1.2e-07 0.00043 1 29 [. 57 85 .. 57 90 .. 0.88 4 ? 2.8 0.0 0.049 1.8e+02 16 30 .] 88 102 .. 84 102 .. 0.87 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.061 EF-hand_6 17 isleElraalrslG 30 ++ +El ++rslG FUN_001688-T1 2 VTEKELGLIMRSLG 15 799*********98 PP == domain 2 score: 0.0 bits; conditional E-value: 0.39 EF-hand_6 13 gdGyisleElraal 26 g+ ++s+ E+ +++ FUN_001688-T1 31 GKQKVSFPEFLKMV 44 67789999*99986 PP == domain 3 score: 20.3 bits; conditional E-value: 1.2e-07 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrsl 29 e+ aF +D++++G++s+++l+++++ FUN_001688-T1 57 EILAAFTALDREKTGSVSRSQLQHLMTGT 85 5788**********************944 PP == domain 4 score: 2.8 bits; conditional E-value: 0.049 EF-hand_6 16 yisleElraalrslG 30 ++ eE+ ++lr lG FUN_001688-T1 88 KLGSEEFDHMLRDLG 102 67889*******998 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.2 7.3e+02 17 29 .] 2 14 .. 1 14 [. 0.87 2 ? -2.3 0.1 1.8 6.5e+03 21 27 .. 22 28 .. 18 30 .. 0.58 3 ! 4.9 0.0 0.0083 30 15 28 .. 33 46 .. 31 47 .. 0.83 4 ! 13.5 0.0 1.5e-05 0.055 1 27 [. 57 83 .. 57 85 .. 0.92 5 ? 1.2 0.0 0.13 4.7e+02 17 28 .. 89 100 .. 88 101 .. 0.80 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.2 EF-hand_1 17 IdfeEfkellkkl 29 ++ +E+ ++++l FUN_001688-T1 2 VTEKELGLIMRSL 14 7999******986 PP == domain 2 score: -2.3 bits; conditional E-value: 1.8 EF-hand_1 21 Efkellk 27 E el++ FUN_001688-T1 22 EIEELMT 28 6666665 PP == domain 3 score: 4.9 bits; conditional E-value: 0.0083 EF-hand_1 15 GkIdfeEfkellkk 28 k++f Ef++++++ FUN_001688-T1 33 QKVSFPEFLKMVAE 46 69*********975 PP == domain 4 score: 13.5 bits; conditional E-value: 1.5e-05 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellk 27 e+ +F +D+ + G ++++++++l++ FUN_001688-T1 57 EILAAFTALDREKTGSVSRSQLQHLMT 83 67789*********************8 PP == domain 5 score: 1.2 bits; conditional E-value: 0.13 EF-hand_1 17 IdfeEfkellkk 28 + eEf ++l++ FUN_001688-T1 89 LGSEEFDHMLRD 100 6679*****987 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.1 0.083 3e+02 12 31 .. 9 27 .. 2 47 .. 0.63 2 ! 10.9 0.0 0.00012 0.42 15 44 .. 47 75 .. 31 84 .. 0.73 3 ! 7.1 0.0 0.0018 6.6 2 34 .. 86 118 .. 85 118 .. 0.91 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.083 EF-hand_8 12 rilalLglqdlsedevdtlf 31 i++ Lg + +++ e+ +l+ FUN_001688-T1 9 LIMRSLGEN-ITNFEIEELM 27 566667777.7777766666 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00012 EF-hand_8 15 alLglqdlsedevdtlfrefDtDgdGkisf 44 ++ +e+e+ + f+++D+++ G++s FUN_001688-T1 47 QTGKMI-STEKEILAAFTALDREKTGSVSR 75 333444.8999*****************97 PP == domain 3 score: 7.1 bits; conditional E-value: 0.0018 EF-hand_8 2 kgvItresLkrilalLglqdlsedevdtlfref 34 +++++ e++ + l++Lgl ++ ++++l+r++ FUN_001688-T1 86 GDKLGSEEFDHMLRDLGLEGCASIQYTDLVRAI 118 68999******99*********99999999986 PP >> EF-hand_SWAP70_N Switch-associated protein 70-like, N-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.0 6.2e-08 0.00023 9 37 .. 55 83 .. 46 116 .. 0.87 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 6.2e-08 EF-hand_SWAP70_N 9 lksiwhaFtaLdveqsgkvsKsqLkVLsh 37 +k i aFtaLd+e++g vs+sqL+ L + FUN_001688-T1 55 EKEILAAFTALDREKTGSVSRSQLQHLMT 83 799*********************97765 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.0 0.0 6.6e-06 0.024 14 80 .. 50 116 .. 40 120 .] 0.89 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 6.6e-06 EF-hand_11 14 avashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdfls 80 + s + i f +d k+ +vsr +++ + t + l e+fd + +l ++ ++y d++ FUN_001688-T1 50 KMISTEKEILAAFTALDREKTGSVSRSQLQHLMTGTGDKLGSEEFDHMLRDLGLEGCASIQYTDLVR 116 556777889999***************************************************9875 PP >> AIF-1 Allograft inflammatory factor 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.1 0.0064 23 66 105 .. 10 46 .. 3 60 .. 0.76 2 ? 6.6 0.0 0.0034 12 47 102 .. 62 117 .. 49 119 .. 0.90 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0064 AIF-1 66 mleklGvakthlelkklisevtggssetisyrdflkmmlG 105 ++ lG + t +e+ l+++ ++ +s+ +flkm+ FUN_001688-T1 10 IMRSLGENITNFEIEELMTKA---GKQKVSFPEFLKMVAE 46 678899999999999998764...4677999999999754 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0034 AIF-1 47 ymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkm 102 + +d++++G + l++++ G e+ +++++ + +i y+d+++ FUN_001688-T1 62 FTALDREKTGSVSRSQLQHLMTGTGDKLGSEEFDHMLRDLGLEGCASIQYTDLVRA 117 67789999*****************99999**********************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 847 (0.0331572); expected 510.9 (0.02) Passed bias filter: 702 (0.0274809); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1203.37 // Query: FUN_001689-T1 [L=69] Description: FUN_001689 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (69 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 437 (0.0171071); expected 510.9 (0.02) Passed bias filter: 368 (0.014406); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.42s 00:00:00.63 Elapsed: 00:00:00.38 # Mc/sec: 724.38 // Query: FUN_001691-T1 [L=412] Description: FUN_001691 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 3.1 8.1 8.1 12 6.2 1.4 2.8 3 Rv3651-like_C Rv3651-like, C-terminal domain Domain annotation for each model (and alignments): >> Rv3651-like_C Rv3651-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.1 0.001 26 22 49 .. 32 59 .. 24 97 .. 0.73 2 ? 6.2 1.4 0.00048 12 27 56 .. 99 127 .. 86 136 .. 0.82 3 ? -1.4 0.1 0.11 2.8e+03 15 28 .. 158 171 .. 153 208 .. 0.72 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.001 Rv3651-like_C 22 dlkswkllkwldepcPfldwraeekees 49 d sw++ k ld+ +l+wr ++ + FUN_001691-T1 32 DDSSWNFAKLLDHCNEYLNWRRSSDVSL 59 7789*****************8875444 PP == domain 2 score: 6.2 bits; conditional E-value: 0.00048 Rv3651-like_C 27 kllkwldepcPfldwraeekeesvvhPdde 56 ++ kw ++ P+l+wr ++ + + +P+d+ FUN_001691-T1 99 RITKWWNNCWPYLEWRKSNVSV-QTDPQDN 127 678*************999654.5678776 PP == domain 3 score: -1.4 bits; conditional E-value: 0.11 Rv3651-like_C 15 gvhralvdlkswkl 28 +++ +vd+k w FUN_001691-T1 158 NIYHKIVDIKRWIT 171 68899999999953 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (412 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2300 (0.0900372); expected 510.9 (0.02) Passed bias filter: 570 (0.0223136); expected 510.9 (0.02) Passed Vit filter: 74 (0.00289685); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.43u 0.35s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 4018.71 // Query: FUN_001692-T1 [L=609] Description: FUN_001692 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.029 15.1 0.0 7.6 7.3 0.0 3.6 4 GLGE_C GLGE, C-terminal 0.052 14.1 2.0 2.7 8.6 0.2 3.8 4 Type_III_YscG Bacterial type III secretion system chaperone 3 8.7 4.6 40 5.1 0.1 3.7 4 OMP10 Outer membrane lipoprotein Omp10 Domain annotation for each model (and alignments): >> GLGE_C GLGE, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.0009 7.6 51 79 .. 214 242 .. 205 246 .. 0.80 2 ? -1.1 0.0 0.37 3.1e+03 54 76 .. 271 293 .. 263 300 .. 0.84 3 ? -0.3 0.0 0.22 1.9e+03 40 76 .. 291 329 .. 276 332 .. 0.74 4 ? 2.0 0.0 0.041 3.5e+02 51 76 .. 358 383 .. 347 387 .. 0.87 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0009 GLGE_C 51 eesfevhDlltgeeyeWgeenyVrLdpek 79 e+ + +Dl+t +y+ +e+nyV+Ld + FUN_001692-T1 214 EADCVSQDLITSGNYNGNEANYVSLDLVA 242 4567789******************9655 PP == domain 2 score: -1.1 bits; conditional E-value: 0.37 GLGE_C 54 fevhDlltgeeyeWgeenyVrLd 76 + +Dl+++ +y+ +e ny +Ld FUN_001692-T1 271 CISSDLISNGNYTGNEVNYESLD 293 5568*********9999998876 PP == domain 3 score: -0.3 bits; conditional E-value: 0.22 GLGE_C 40 eldlealgleeee..sfevhDlltgeeyeWgeenyVrLd 76 +ldl a+g +++ ++ Dl+ + +y+ +e+ny +Ld FUN_001692-T1 291 SLDLIAIGNPTGNeaNCISLDLIANGNYNGNEANYESLD 329 577777777654411555679999999999999997776 PP == domain 4 score: 2.0 bits; conditional E-value: 0.041 GLGE_C 51 eesfevhDlltgeeyeWgeenyVrLd 76 e++++ +Dl+++ +++ +e nyV+Ld FUN_001692-T1 358 EANCTSSDLISNGNHTGNEVNYVSLD 383 5678889*****************98 PP >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.2 0.00032 2.7 11 55 .. 237 282 .. 229 285 .. 0.75 2 ? 5.2 0.1 0.0034 29 14 37 .. 258 281 .. 251 318 .. 0.84 3 ? 0.7 0.0 0.091 7.8e+02 11 36 .. 291 316 .. 283 335 .. 0.77 4 ? 0.1 0.0 0.13 1.1e+03 14 39 .. 348 373 .. 346 398 .. 0.63 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00032 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgeeeaarlirlss.lanqGky 55 + lv G h +ean+i+ l +g+ + +ss l+ +G+y FUN_001692-T1 237 SLDLVADGTHNGNEANCISSDLIGNGNSAGNEANCISSdLISNGNY 282 6789999999999999999999888887555544454437788887 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0034 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkge 37 l+G G+ +ean+i+ l ++g+ FUN_001692-T1 258 LIGNGNSAGNEANCISSDLISNGN 281 89*************998887765 PP == domain 3 score: 0.7 bits; conditional E-value: 0.091 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkg 36 + l+ G+ +ean+i+ l +g FUN_001692-T1 291 SLDLIAIGNPTGNEANCISLDLIANG 316 578999999999*****986665544 PP == domain 4 score: 0.1 bits; conditional E-value: 0.13 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkgeee 39 l+ G+ +ean+ + l ++g++ FUN_001692-T1 348 LIADGNSTGNEANCTSSDLISNGNHT 373 56677777777777777666666552 PP >> OMP10 Outer membrane lipoprotein Omp10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.0046 40 27 62 .. 219 254 .. 210 258 .. 0.87 2 ? 2.0 0.0 0.043 3.7e+02 28 62 .. 274 308 .. 259 312 .. 0.86 3 ? -0.8 0.0 0.32 2.7e+03 31 51 .. 313 333 .. 309 365 .. 0.71 4 ? -0.2 0.1 0.21 1.8e+03 27 59 .. 363 395 .. 340 397 .. 0.72 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0046 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskvnCa 62 +++ +++G+Y+ ++a+ v+++l +++ ++nC FUN_001692-T1 219 SQDLITSGNYNGNEANYVSLDLVADGTHNGNEANCI 254 566889**********************99****95 PP == domain 2 score: 2.0 bits; conditional E-value: 0.043 OMP10 28 gekLaeGtYtktsaklveieltslvrktqskvnCa 62 + +++G+Yt ++ + +++l + + t ++nC FUN_001692-T1 274 SDLISNGNYTGNEVNYESLDLIAIGNPTGNEANCI 308 567899*******99999**999999999999995 PP == domain 3 score: -0.8 bits; conditional E-value: 0.32 OMP10 31 LaeGtYtktsaklveieltsl 51 +a+G+Y+ ++a+ +++l + FUN_001692-T1 313 IANGNYNGNEANYESLDLIAI 333 688888888777666666554 PP == domain 4 score: -0.2 bits; conditional E-value: 0.21 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskv 59 + + +++G+ t ++ + v+++l + ++t ++ FUN_001692-T1 363 SSDLISNGNHTGNEVNYVSLDLIAIGNQTGNEA 395 345678899998888888888888888877666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (609 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 442 (0.0173028); expected 510.9 (0.02) Passed bias filter: 375 (0.01468); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 5910.44 // Query: FUN_001693-T1 [L=113] Description: FUN_001693 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-07 29.2 0.4 2e-06 27.5 0.2 1.9 2 EF-hand_6 EF-hand domain 8.8e-07 29.7 0.2 1.3e-06 29.1 0.2 1.2 1 EF-hand_7 EF-hand domain pair 1.1e-05 25.1 0.3 1.1e-05 25.1 0.3 2.5 3 EF-hand_1 EF hand domain 0.003 17.5 0.3 0.003 17.5 0.3 1.7 2 EF-hand_5 EF hand ------ inclusion threshold ------ 0.011 16.5 0.3 0.013 16.2 0.3 1.1 1 AIF-1 Allograft inflammatory factor 1 Domain annotation for each model (and alignments): >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 0.2 3.9e-10 2e-06 1 30 [] 32 61 .. 32 61 .. 0.96 2 ? -1.7 0.0 1 5.1e+03 18 27 .. 82 91 .. 79 95 .. 0.74 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 3.9e-10 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrslG 30 +++e+F+lfD d dG ++ +El ++rslG FUN_001693-T1 32 QFKECFNLFDGDSDGMVTEKELGLIMRSLG 61 589*************************98 PP == domain 2 score: -1.7 bits; conditional E-value: 1 EF-hand_6 18 sleElraalr 27 + E+ ++l FUN_001693-T1 82 RFPEFLKMLA 91 5679999986 PP >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.1 0.2 2.6e-10 1.3e-06 4 66 .. 33 90 .. 31 91 .. 0.88 Alignments for each domain: == domain 1 score: 29.1 bits; conditional E-value: 2.6e-10 EF-hand_7 4 lkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 ke+F+l+D d dG ++++el l+ + ++ge+++ e+eel+ ++ + +++f EFl+++ FUN_001693-T1 33 FKECFNLFDGDSDGMVTEKELG-LIMR-SLGENITNFEIEELMTKAAKQ---KVRFPEFLKML 90 589*******************.6666.*************98885555...5*******985 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.3 2.2e-09 1.1e-05 2 29 .] 33 60 .. 32 60 .. 0.95 2 ? -2.2 0.1 1.2 6e+03 21 27 .. 68 74 .. 64 76 .. 0.58 3 ? 0.1 0.0 0.2 1e+03 19 27 .. 83 91 .. 79 93 .. 0.80 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 2.2e-09 EF-hand_1 2 lkeiFrefDkDgdGkIdfeEfkellkkl 29 +ke F++fD D dG ++ +E+ ++++l FUN_001693-T1 33 FKECFNLFDGDSDGMVTEKELGLIMRSL 60 89***********************986 PP == domain 2 score: -2.2 bits; conditional E-value: 1.2 EF-hand_1 21 Efkellk 27 E el++ FUN_001693-T1 68 EIEELMT 74 6666665 PP == domain 3 score: 0.1 bits; conditional E-value: 0.2 EF-hand_1 19 feEfkellk 27 f Ef+++l+ FUN_001693-T1 83 FPEFLKMLA 91 789**9997 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.3 5.9e-07 0.003 1 23 [. 33 55 .. 33 57 .. 0.89 2 ? -3.3 0.1 2.2 1.1e+04 18 22 .. 69 73 .. 68 74 .. 0.70 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 5.9e-07 EF-hand_5 1 lkdtFraiDlNgDGkIskeELkr 23 +k++F+ +D + DG ++ +EL FUN_001693-T1 33 FKECFNLFDGDSDGMVTEKELGL 55 5889****************975 PP == domain 2 score: -3.3 bits; conditional E-value: 2.2 EF-hand_5 18 keELk 22 eEL+ FUN_001693-T1 69 IEELM 73 58987 PP >> AIF-1 Allograft inflammatory factor 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.2 0.3 2.5e-06 0.013 33 106 .. 23 93 .. 9 105 .. 0.83 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.5e-06 AIF-1 33 eedleskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmmlGk 106 e+ ++ +fk+ + fd + +G + l ++ lG + t +e+ l+++ ++++ + + +flkm+ + FUN_001693-T1 23 EDPINIAKGQFKECFNLFDGDSDGMVTEKELGLIMRSLGENITNFEIEELMTK---AAKQKVRFPEFLKMLAER 93 4455666678****************************************975...5678899*****997543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 764 (0.029908); expected 510.9 (0.02) Passed bias filter: 656 (0.0256802); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1156.09 // Query: FUN_001695-T1 [L=69] Description: FUN_001695 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (69 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 433 (0.0169505); expected 510.9 (0.02) Passed bias filter: 361 (0.0141319); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 703.21 // Query: FUN_001698-T1 [L=332] Description: FUN_001698 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-40 138.7 5.9 3.8e-40 138.5 5.9 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 3.6e-06 27.0 11.0 5.8e-06 26.4 11.0 1.3 1 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv 0.0069 16.7 6.2 0.01 16.1 6.3 1.3 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 1.1 9.9 0.0 1.1 9.9 0.0 2.6 3 Sid-5 Sid-5 family 1.6 8.6 2.8 3.6 7.5 2.8 1.5 1 DUF3671 Fam-L, Fam-M like protein Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.5 5.9 7.4e-44 3.8e-40 1 189 [. 53 242 .. 53 305 .. 0.89 Alignments for each domain: == domain 1 score: 138.5 bits; conditional E-value: 7.4e-44 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvf...gevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+lVi+v rn++lrt ++ f++n+a+aDl+++++++p +++ ++ +++w g v+Ck++ +l+ v+ ++s+l+l+ais+DRY aI+ p+k FUN_001698-T1 53 GNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESVIVEIrNTDQWFPgevGVVMCKFWPFLQQVCAFCSVLSLLAISLDRYFAICLPFK 148 8*****************************************9999555666544446788*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakk 186 + i+++++ +vlil++W+l ++ s p+++ ++ + ++e Cl +p+ + +++ yt++l+vl+++ pl+vi+++y++++ ++++++ FUN_001698-T1 149 R--IMSQKLSTVLILLTWLLPVVSSAPMFVANNVVEI---SGELLCLEAWPSpfDPVKAHTDYTIILFVLFYVFPLTVISFLYSLVIFKIWRRRVP 239 9..***************************8888777...89**********65555599********************************9987 PP xxx RF 7tm_1 187 eks 189 e s FUN_001698-T1 240 EIS 242 755 PP >> 7TM_GPCR_Srv Serpentine type 7TM GPCR chemoreceptor Srv # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 11.0 1.1e-09 5.8e-06 15 187 .. 55 230 .. 42 253 .. 0.76 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 1.1e-09 7TM_GPCR_Srv 15 ilicllklrkrsktfkttFYklllqhaiaDiitllvyivgavfrklgwieefyfelqeyy.aaiyyniayytliirctgivlLslqRllaillPis 109 il++ ++ r+r+ ++t Y+ ++ aiaD++t ++++ v+ +++ + + + ++ +++ + + + +sl R++ai+lP FUN_001698-T1 55 ILVITVSRRNRN--LRTIAYSFVINMAIADLMTTVINMPESVIVEIRNTDQWFPGEVGVVmCKFWPFLQQVCAFCSVLSLLAISLDRYFAICLPF- 147 566666777777..********************************999998887777776999999999*************************. PP 7TM_GPCR_Srv 110 rltkivqsaklwkiilvywlvgllislvvlkdtdieydneen.....mpvvadksvierftlialivvv..vtciiliiayvllf 187 ++i++++ + +il+ wl +++ s+ +++ +++ ++ e p d+ ++ ++i l+v++ + +++++y+l++ FUN_001698-T1 148 --KRIMSQKLSTVLILLTWLLPVVSSAPMFVANNVVEISGELlcleaWPSPFDPVKAHTDYTIILFVLFyvFPLTVISFLYSLVI 230 ..8999999999999*************999988877776665544434444444444444444333330033334444444333 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 6.3 2e-06 0.01 3 111 .. 45 156 .. 42 236 .. 0.71 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 2e-06 7tm_4 3 lvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdar......eisfeacllqlffihkfsllesavllamavdr 92 ++ + +l Gn+ ++ v + ++ l y f+ +a++dl ++ +P+ + + + ++ e+ c + f+ ++ +lla+++dr FUN_001698-T1 45 VIIIASLEGNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESVIVE-IRNTdqwfpgEVGVVMCKFWPFLQQVCAFCSVLSLLAISLDR 139 45566899***************************************976443.333312233367777788888877788899999********* PP 7tm_4 93 fvaiysplryteiltnkvi 111 + ai+ p++ i+++k FUN_001698-T1 140 YFAICLPFK--RIMSQKLS 156 *****9976..45555522 PP >> Sid-5 Sid-5 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.7 1.1 5.4e+03 19 45 .. 43 69 .. 37 100 .. 0.67 2 ? 9.9 0.0 0.00022 1.1 16 55 .. 204 243 .. 198 259 .. 0.83 3 ? -1.4 0.1 0.76 3.9e+03 39 53 .. 288 302 .. 284 312 .. 0.83 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 1.1 Sid-5 19 lLaisilllllNilqvvffnRakllkl 45 lL+i+i l Nil + R++ l+ FUN_001698-T1 43 LLVIIIASLEGNILVITVSRRNRNLRT 69 555555555556666666666655544 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00022 Sid-5 16 cvilLaisilllllNilqvvffnRakllklyRrrfqqlPe 55 ++ +++++l+ ++ + + f++ ++k+ Rrr+ ++ FUN_001698-T1 204 TDYTIILFVLFYVFPLTVISFLYSLVIFKIWRRRVPEISP 243 67888899999999999*****************998865 PP == domain 3 score: -1.4 bits; conditional E-value: 0.76 Sid-5 39 RakllklyRrrfqql 53 R ++ ++ Rrr+++ FUN_001698-T1 288 RVRIARFRRRRVDPY 302 88999*****99875 PP >> DUF3671 Fam-L, Fam-M like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 2.8 0.0007 3.6 151 208 .. 147 233 .. 145 237 .. 0.69 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0007 DUF3671 151 lkkiirkkyglrialpllflllllllsllldls.............................lfgiliylvpfiilgiiiilgiiyi 208 +k+i+ +k++ ++l+ +l ++ + ++++ + ++++l+y+ p+ +++++ l+i++i FUN_001698-T1 147 FKRIMSQKLSTVLILLTWLLPVVSSAPMFVANNvveisgellcleawpspfdpvkahtdytiILFVLFYVFPLTVISFLYSLVIFKI 233 699999999999999999666666666553222667778888888999999999999655555555556666666666666666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1032 (0.0403993); expected 510.9 (0.02) Passed bias filter: 543 (0.0212566); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3356.97 // Query: FUN_001699-T1 [L=805] Description: FUN_001699 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.052 14.2 0.0 7.7 7.3 0.0 2.6 2 GLGE_C GLGE, C-terminal Domain annotation for each model (and alignments): >> GLGE_C GLGE, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.0003 7.7 56 79 .. 126 149 .. 112 154 .. 0.81 2 ? 4.0 0.0 0.0032 82 53 76 .. 177 200 .. 163 203 .. 0.86 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0003 GLGE_C 56 vhDlltgeeyeWgeenyVrLdpek 79 +Dl+t+ +y+ +e+nyV+Ld + FUN_001699-T1 126 SQDLITNGNYTGNEANYVSLDLIA 149 58******************9665 PP == domain 2 score: 4.0 bits; conditional E-value: 0.0032 GLGE_C 53 sfevhDlltgeeyeWgeenyVrLd 76 ++ +Dl+++ +y+ +e nyV+Ld FUN_001699-T1 177 NCISSDLISNGNYTGNEVNYVSLD 200 55668*****************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (805 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1825 (0.0714426); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.43u 0.42s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 7722.12 // Query: FUN_001700-T1 [L=270] Description: FUN_001700 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0013 19.3 0.3 0.0013 19.3 0.3 2.1 2 Integrase_p58_C Integrase p58, C-terminal domain Domain annotation for each model (and alignments): >> Integrase_p58_C Integrase p58, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.6 0.44 1.1e+04 14 24 .. 103 113 .. 99 114 .. 0.57 2 ! 19.3 0.3 5e-08 0.0013 2 22 .. 121 141 .. 121 149 .. 0.82 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 0.44 Integrase_p58_C 14 YrIqkperrkk 24 Yr + + rrkk FUN_001700-T1 103 YRNRTRTRRKK 113 66566655554 PP == domain 2 score: 19.3 bits; conditional E-value: 5e-08 Integrase_p58_C 2 PYrVvkklsdVtYrIqkperr 22 P++V+k l dVtYrI +rr FUN_001700-T1 121 PWKVLKALPDVTYRIAEERRR 141 9***************96433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (270 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1049 (0.0410648); expected 510.9 (0.02) Passed bias filter: 633 (0.0247798); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 2734.68 // Query: FUN_001701-T1 [L=179] Description: FUN_001701 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 558 (0.0218438); expected 510.9 (0.02) Passed bias filter: 349 (0.0136622); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1820.70 // Query: FUN_001702-T1 [L=584] Description: FUN_001702 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00035 21.1 0.1 0.0007 20.2 0.1 1.4 1 SPRY SPRY domain 0.00076 19.2 4.3 0.0012 18.6 4.3 1.2 1 AIP3 Actin interacting protein 3 0.0016 18.6 0.6 0.0033 17.6 0.6 1.4 1 Tetraspanin Tetraspanin family 0.0034 17.1 0.4 0.0052 16.5 0.4 1.2 1 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.013 16.9 2.8 0.71 11.4 0.1 2.8 2 Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain 0.05 14.2 8.8 1.6 9.3 2.1 2.5 2 Sec10_N Exocyst complex component Sec10, N-terminal 0.17 12.7 7.6 0.41 11.4 1.3 2.4 2 Spectrin_Anc-1 Nuclear anchorage protein 1, spectrin-like re 0.39 11.0 10.0 0.5 10.6 1.9 2.6 2 Syntaxin Syntaxin 0.75 10.5 5.4 5 7.9 0.9 2.4 2 HisK-N-like HisK-N-like globin domain of the ASK signalos 1.1 10.0 6.7 5.5 7.7 0.3 2.5 2 DUF29 Domain of unknown function DUF29 1.1 9.9 11.5 1.6 9.4 1.2 2.6 2 OmpH Outer membrane protein (OmpH-like) 1.1 9.7 0.0 1.1 9.7 0.0 2.7 2 HEPN-like_int HEPN-like integron domain 1.5 8.4 5.6 0.49 10.1 0.8 2.0 2 ISG65-75 Invariant surface glycoprotein 1.7 9.3 5.1 5.5 7.7 0.5 2.4 2 Fib_alpha Fibrinogen alpha/beta chain family 2.6 9.4 7.2 8.3 7.7 0.6 2.6 2 Occludin_ELL Occludin homology domain 3 8.0 12.7 0.44 10.7 2.4 2.3 2 TACC_C Transforming acidic coiled-coil-containing pr 3.1 7.9 14.1 1.1 9.4 5.0 2.3 2 FAM184 Family with sequence similarity 184, A and B 3.5 8.1 5.8 7.4 7.1 1.4 2.4 2 DUF1664 Protein of unknown function (DUF1664) 6.9 6.9 7.8 0.87 9.9 1.3 2.1 2 Bacillus_HBL Bacillus haemolytic enterotoxin (HBL) 7.2 7.7 8.6 2.6 9.2 1.0 2.5 2 YabA Initiation control protein YabA Domain annotation for each model (and alignments): >> SPRY SPRY domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.1 5.5e-07 0.0007 4 108 .. 236 351 .. 234 362 .. 0.75 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 5.5e-07 SPRY 4 feveve.gqekgsvrvGvatksvprkgekflgdeegswgydgwkgkky...sastsestglplfeegdviGcflDleeg.....eisFtkng.ksl 89 fev ++ +++ + +G + + g+ ++g+ +g +gy+ ++gk++ + ++++ ++ + gd iGc + +e + Ft ng + + FUN_001702-T1 236 FEVLIQeTGDRRFLGIGAVWRGYG-AGHSMPGWSKGTVGYHVDDGKIFhakNPYKGKEVEDAMAYRGDLIGCTIKFEGItngqvPVVFTLNGrRIT 330 899999888999999999999998.99********************9666666778888888889*********996533344588888885333 PP SPRY 90 ..gvaFrkvsfagklfPavsl 108 ++ ++ + ++P++++ FUN_001702-T1 331 qdEIWIDYTPGGKLMYPYIAM 351 224444444444566777766 PP >> AIP3 Actin interacting protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 4.3 9.5e-07 0.0012 64 190 .. 393 560 .. 386 563 .. 0.86 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 9.5e-07 AIP3 64 rsvLsLniekldevkkhideslasllkelkelkssiesqkasaqevserqeeaakekaeesla................................. 126 + v+ + + ++e+k+ +d ++++ke++e+++++++ k+++q ++++ +++ k+ ++ + FUN_001702-T1 393 QLVIAMALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKRVKKMFFFddrrrygplllprdvsgheefstvsqldlrlie 488 5577888999***********************************9999999999888844449******************************** PP AIP3 127 .........kkdlkaqlkevqslrrdLavlrqlysefkseikesiselrekakkvkeaslastkkssnrayie 190 +++ ++ ++ +rr+L+ l + +++++e+ +++++l+++a +++++sl+s++++ +++++e FUN_001702-T1 489 tweseveeeERKVPIIVDLLRMIRRELEDLGKKTKKKTDEMLKELAQLKNEA-QFQHLSLKSKNEGLDKNFLE 560 **99987766666677888889999999999888999999999999998886.47778888888887777765 PP >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.6 2.6e-06 0.0033 76 153 .. 30 111 .. 19 135 .. 0.69 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 2.6e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxx.xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxx....x RF Tetraspanin 76 lllyfvlllllflaelaagilafvyrdk..ekeelsnw.lkksledsyedasdlkskke..ealdslqeelkCCGvnsysDw....e 153 +ly +l++ ++++ + i+++ ++ + ++++l +w +kk++ ++++s+++ ++++ lkCCG+++ +w + FUN_001702-T1 30 HFLYGAFLVMGAILLINMMIALLSNTYQkvQDNSLMEWsFKKAIT-----IQTYSSCDPipVPVNFVSLMLKCCGWQKCFNWcrnrK 111 466778888888888888886666666633444445554555552.....233344444779********************43220 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.4 4e-06 0.0052 206 241 .. 27 62 .. 9 64 .. 0.86 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 4e-06 Ion_trans 206 aiaviyfvlfiilggvlllnlliaviidnfqelter 241 ++ ++++ f+++g++ll+n++ia++++++q+++++ FUN_001702-T1 27 MLVHFLYGAFLVMGAILLINMMIALLSNTYQKVQDN 62 5677899*************************9976 PP >> Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.3 0.072 92 20 65 .. 408 453 .. 390 455 .. 0.71 2 ? 11.4 0.1 0.00055 0.71 27 73 .. 519 566 .. 496 568 .. 0.81 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.072 Myb_DNA-bind_3 20 kgnriegntfkkeawkeileefna.ktgakytkeqlknrlkklrkqy 65 + + +tfkke +ei +++n+ k ++++ +++l +k+++k + FUN_001702-T1 408 ETVDADRKTFKKE-VEEIRNHLNNaKEESQALESKLSDSFKRVKKMF 453 3333566788887.889999998888888888888888888888765 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00055 Myb_DNA-bind_3 27 ntfkkeawkeileefna.ktgakytkeqlknrlkklrkqyklvkelle 73 +k++ +e+l+e+ + k++a++++ lk++ + l k++ ++el++ FUN_001702-T1 519 GKKTKKKTDEMLKELAQlKNEAQFQHLSLKSKNEGLDKNFLEIEELIQ 566 44467789********************************99999876 PP >> Sec10_N Exocyst complex component Sec10, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 2.1 0.0012 1.6 23 71 .. 400 448 .. 388 452 .. 0.86 2 ? 8.2 0.6 0.0028 3.6 11 66 .. 511 566 .. 502 574 .. 0.89 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0012 Sec10_N 23 qekeqklekavrqaeakhskklneLskkldqivdsfqqLdekisevgqk 71 ++ +++++ v+ ++++k+++e+++ l+++ ++ q+L++k+s+ ++ FUN_001702-T1 400 LNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKR 448 57788999***********************************986555 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0028 Sec10_N 11 alkeLkeLqeqvqekeqklekavrqaeakhskklneLskkldqivdsfqqLdekis 66 + +eL++L +++++k++++ k+++q +++ + + + L++k++ + ++f +++e i+ FUN_001702-T1 511 IRRELEDLGKKTKKKTDEMLKELAQLKNEAQFQHLSLKSKNEGLDKNFLEIEELIQ 566 457************************99999999999999999999999998876 PP >> Spectrin_Anc-1 Nuclear anchorage protein 1, spectrin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.6 0.047 61 15 40 .. 416 441 .. 398 453 .. 0.50 2 ? 11.4 1.3 0.00032 0.41 23 64 .. 504 544 .. 479 556 .. 0.80 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.047 Spectrin_Anc-1 15 eFvkerdeandqLdklrkpLdeieek 40 +F+ke +e+ ++L++++++ +++e+k FUN_001702-T1 416 TFKKEVEEIRNHLNNAKEESQALESK 441 34444444444444444444443333 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00032 Spectrin_Anc-1 23 andqLdklrkpLdeieekslrsldeaeedleklkkaseelsk 64 + d L +r++L+++ +k++ ++de++++l +lk++ + +++ FUN_001702-T1 504 IVDLLRMIRRELEDLGKKTKKKTDEMLKELAQLKNEAQ-FQH 544 5678899***************************9765.444 PP >> Syntaxin Syntaxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 1.9 0.00039 0.5 34 81 .. 395 442 .. 370 453 .. 0.83 2 ? 4.4 1.3 0.033 42 33 76 .. 499 542 .. 474 557 .. 0.76 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00039 Syntaxin 34 klltkarrlkklkkrmesdikevkkraesikarLealdksneenekks 81 + + + +k++k+ +++d k+ kk+ e+i++ L++ ++++++ e+k FUN_001702-T1 395 VIAMALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKL 442 566677899*********************************998753 PP == domain 2 score: 4.4 bits; conditional E-value: 0.033 Syntaxin 33 sklltkarrlkklkkrmesdikevkkraesikarLealdksnee 76 k+ ++ l+ +++++e k+ kk+ +++ ++L +l+++++ FUN_001702-T1 499 RKVPIIVDLLRMIRRELEDLGKKTKKKTDEMLKELAQLKNEAQF 542 55555566678899999999999999999999999999988764 PP >> HisK-N-like HisK-N-like globin domain of the ASK signalosome # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.2 0.05 63 37 91 .. 387 443 .. 369 453 .. 0.68 2 ? 7.9 0.9 0.0039 5 22 83 .. 484 547 .. 472 554 .. 0.85 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.05 HisK-N-like 37 eelklkkehlkqllsglreyir..kkdrkqleeaikelkeeldfdstainqlqlaly 91 ++l+l++ ++++ l+ ++e + + drk+ +++++e++++l++ +++ + l++ l FUN_001702-T1 387 SDLELEQLVIAMALNDVKEIKEtvDADRKTFKKEVEEIRNHLNNAKEESQALESKLS 443 455566666666665555543311567889999999***999999999999998886 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0039 HisK-N-like 22 ekiisawleslkqsseelklkkehlkqllsglreyirkkdrk..qleeaikelkeeldfdstai 83 ++i++w+++++++++++ + + l+++ + l++ +k+++k ++ +++++lk+e +f++ ++ FUN_001702-T1 484 LRLIETWESEVEEEERKVPIIVDLLRMIRRELEDLGKKTKKKtdEMLKELAQLKNEAQFQHLSL 547 5789************************999999887766554588899999999999987665 PP >> DUF29 Domain of unknown function DUF29 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.3 0.0043 5.5 58 101 .. 404 448 .. 382 451 .. 0.80 2 ? 4.5 1.5 0.04 52 30 77 .. 511 557 .. 489 574 .. 0.71 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0043 DUF29 58 k.weyqpekrsksweaeikeqrkeieklLedspsLknyleealee 101 k +++ + ++k +++e++e r+++++ e+s+ L+++l++++++ FUN_001702-T1 404 KeIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKR 448 356777788999****************************99986 PP == domain 2 score: 4.5 bits; conditional E-value: 0.04 DUF29 30 LieEieslgrsekrelesrLevllehlLkweyqpekrsksweaeikeq 77 + E+e+lg++ k++ + L+ l + + ++q + + ks ++ ++ FUN_001702-T1 511 IRRELEDLGKKTKKKTDEMLKELAQLKNEAQFQ-HLSLKSKNEGLDKN 557 457******************997633334444.23444444555555 PP >> OmpH Outer membrane protein (OmpH-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 1.2 0.0012 1.6 12 57 .. 398 443 .. 393 460 .. 0.78 2 ? 4.5 3.3 0.04 51 20 62 .. 511 556 .. 506 567 .. 0.74 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.0012 OmpH 12 eespegkaaqkqlekefkkrqkelekkekelqklqeklqaeasels 57 + ++ k++++++++ k+++ke+e+ ++ l++ +e+ qa s+ls FUN_001702-T1 398 MALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLS 443 567889999***********************99999986544443 PP == domain 2 score: 4.5 bits; conditional E-value: 0.04 OmpH 20 aqkqlekefkkrqkelekkekelqklqeklq.aeasels.se.kee 62 ++++le++ kk +k+ +++ kel +l+++ q + +s +s +e + FUN_001702-T1 511 IRRELEDLGKKTKKKTDEMLKELAQLKNEAQfQHLSLKSkNEgLDK 556 678999*********************9999766555444444444 PP >> HEPN-like_int HEPN-like integron domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.3 1.6 2e+03 89 113 .. 440 461 .. 391 467 .. 0.59 2 ? 9.7 0.0 0.0009 1.1 115 150 .. 539 576 .. 498 577 .. 0.76 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1.6 HEPN-like_int 89 thlpefnksvnefrkifftqdlrly 113 ++ + s + ++k+ff +d r y FUN_001702-T1 440 SK---LSDSFKRVKKMFFFDDRRRY 461 33...33455556677777777766 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0009 HEPN-like_int 115 ntyvahhsdknkd..ksdnflnyeeliqtfckiigvdl 150 ++ h s k k+ nfl+ eeliq c i + l FUN_001702-T1 539 EAQFQHLSLKSKNegLDKNFLEIEELIQGCCTIKKIPL 576 455566665555411578*************9987766 PP >> ISG65-75 Invariant surface glycoprotein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.8 0.00038 0.49 53 126 .. 376 449 .. 350 453 .. 0.74 2 ? 0.4 0.3 0.34 4.3e+02 77 110 .. 515 542 .. 475 568 .. 0.48 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00038 ISG65-75 53 dylvektqekaayiedavkrvkyylekveklkdekkgkakksesavekikelleeAkaaikkakeevkkaaeki 126 + ++ + +e ++ + l+ v+++k+ +++ k+ ++ ve+i+++l++Ak++++ ++++ + + FUN_001702-T1 376 RTITRESGSRGSDLELEQLVIAMALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKRV 449 45666666677777888888999999999999999999999999999999999999999988887777666555 PP == domain 2 score: 0.4 bits; conditional E-value: 0.34 ISG65-75 77 lekveklkdekkgkakksesavekikelleeAka 110 le d +k+ kk+++ +++ +l +eA+ FUN_001702-T1 515 LE------DLGKKTKKKTDEMLKELAQLKNEAQF 542 22......22222333333444444444444432 PP >> Fib_alpha Fibrinogen alpha/beta chain family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.5 0.0043 5.5 21 57 .. 405 441 .. 402 454 .. 0.77 2 ? 3.1 0.4 0.11 1.4e+02 38 130 .. 509 527 .. 470 571 .. 0.48 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0043 Fib_alpha 21 elqdlllkqekevkkdiekLeneleelsnstkeakel 57 e++++++ k++kk++e+++n+l++++++++ ++ FUN_001702-T1 405 EIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESK 441 5788888889999999999999999888888766554 PP == domain 2 score: 3.1 bits; conditional E-value: 0.11 Fib_alpha 38 ekLeneleelsnstkeakelvkaikdslrerqkskkdndnvvkkvskeleeeiaklketvdeqesnirvLqevlesnrqkiqkLeqdidqkee 130 + +++ele+l ++ ++k++ FUN_001702-T1 509 RMIRRELEDL--------------------------------------------------------------------------GKKTKKKTD 527 2233333333..........................................................................222222221 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.6 0.0065 8.3 25 80 .. 404 459 .. 398 464 .. 0.74 2 ? 4.1 1.1 0.088 1.1e+02 45 96 .. 512 565 .. 489 567 .. 0.68 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0065 Occludin_ELL 25 keLhaeleavskkfskleeelkslkegsk.eykkiaeeilqeykklkkdpeylekkk 80 ke++++++a +k f+k ee++++ ++ k e + +++++ +++k++kk + ++++ FUN_001702-T1 404 KEIKETVDADRKTFKKEVEEIRNHLNNAKeESQALESKLSDSFKRVKKMF-FFDDRR 459 7899999999****9866666655555554999999*********97654.444444 PP == domain 2 score: 4.1 bits; conditional E-value: 0.088 Occludin_ELL 45 lkslkegskeykkiaeeilqeykklkkdpeyl..ekkkrceyLkekLshiKkli 96 ++l++ k+ kk ++e+l+e+ +lk++++++ + k++ e L + i +li FUN_001702-T1 512 RRELEDLGKKTKKKTDEMLKELAQLKNEAQFQhlSLKSKNEGLDKNFLEIEELI 565 344555556777888888999999999776651156777777777777776666 PP >> TACC_C Transforming acidic coiled-coil-containing protein (TACC), C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 2.4 0.00035 0.44 44 101 .. 395 452 .. 365 453 .. 0.88 2 ? 2.3 2.8 0.13 1.7e+02 24 99 .. 487 562 .. 474 571 .. 0.71 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00035 TACC_C 44 iveefektiaqlieekqkqkeleeaeiqkvleekeqaladlnsveksfsdlfkryekl 101 +++ + ++++ e +++++ +++e++++ + ++a+++ + +e ++sd fkr++k+ FUN_001702-T1 395 VIAMALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKRVKKM 452 4566677899999*******************************************98 PP == domain 2 score: 2.3 bits; conditional E-value: 0.13 TACC_C 24 iqelkkkveelkkeneemkkiveefektiaqlieekqkqkeleeaeiqkvleekeqaladlnsveksfsdlfkrye 99 i+ ++++vee+++++ + +++ + +++l ++ +k+ +e++++++e + +l+s ++ ++ f +e FUN_001702-T1 487 IETWESEVEEEERKVPIIVDLLRMIRRELEDLGKKTKKKTDEMLKELAQLKNEAQFQHLSLKSKNEGLDKNFLEIE 562 4557777777777777777777777777777777777777777777777777777777777777776666665555 PP >> FAM184 Family with sequence similarity 184, A and B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 1.7 0.058 75 128 168 .. 404 444 .. 363 452 .. 0.59 2 ? 9.4 5.0 0.00084 1.1 120 191 .. 488 561 .. 481 567 .. 0.85 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.058 FAM184 128 qekrkaleelkakhrqEveeLlktskaksasvlkeqeklee 168 +e ++ ++ ++++++Evee+ ++ ++ ++++++ +kl++ FUN_001702-T1 404 KEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSD 444 34444444445555555555555555555555555555544 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00084 FAM184 120 aqlqaqleqekrka..leelkakhrqEveeLlktskaksasvlkeqekleelhkaeveslkeeveelkkekkkl 191 + ++++e+e+rk+ + +l + r+E+e+L k++k+k+ ++lke +l++ + + slk + e l+k+ ++ FUN_001702-T1 488 ETWESEVEEEERKVpiIVDLLRMIRRELEDLGKKTKKKTDEMLKELAQLKNEAQFQHLSLKSKNEGLDKNFLEI 561 566788899999988966766667********************************99***9999999987766 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 1.4 0.0058 7.4 48 91 .. 401 444 .. 390 453 .. 0.60 2 ? 2.5 0.2 0.16 2e+02 30 64 .. 506 540 .. 491 568 .. 0.70 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0058 DUF1664 48 kqleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevte 91 +++++++e++ a +k ++++++++ ++l++ ke s+++++++ + FUN_001702-T1 401 NDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSD 444 34455566666666666666666666666666666666655544 PP == domain 2 score: 2.5 bits; conditional E-value: 0.16 DUF1664 30 DlmfvTkrnlsdavesvskqleqvseslaatKkeL 64 Dl+ +r l+d ++ k+ +++ ++la+ K+e FUN_001702-T1 506 DLLRMIRRELEDLGKKTKKKTDEMLKELAQLKNEA 540 67777777777777777777777777777777653 PP >> Bacillus_HBL Bacillus haemolytic enterotoxin (HBL) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 1.3 0.00068 0.87 124 175 .. 399 450 .. 389 452 .. 0.89 2 ? 0.4 0.7 0.54 6.9e+02 115 149 .. 520 554 .. 504 560 .. 0.69 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00068 Bacillus_HBL 124 lieeLkklklklakdsknFktdvdeltsilagdsgvisqlkneiedlqgsik 175 ++++k+ k+ +++d k+Fk++v+e+ + l++ + + ++l+ +++d + +k FUN_001702-T1 399 ALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKRVK 450 5789999**********************************99999877776 PP == domain 2 score: 0.4 bits; conditional E-value: 0.54 Bacillus_HBL 115 qqnqkevkqlieeLkklklklakdsknFktdvdel 149 + +k++++ ++eL +lk++ + ++k++ + l FUN_001702-T1 520 KKTKKKTDEMLKELAQLKNEAQFQHLSLKSKNEGL 554 45667777778888888877777666666666655 PP >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 1.0 0.002 2.6 21 77 .. 397 453 .. 386 455 .. 0.82 2 ? 2.0 1.3 0.35 4.4e+02 4 31 .. 513 540 .. 479 566 .. 0.65 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.002 YabA 21 lkeleelkeelaelleenaeLeiEnekLrerlkkeeekekekkkelsegkenLaklY 77 l+++ke +++ + ++++ E e++r++l++++e++++ +++ls++ + ++k++ FUN_001702-T1 397 AMALNDVKEIKETVDADRKTFKKEVEEIRNHLNNAKEESQALESKLSDSFKRVKKMF 453 44567777777777789999************9999999999999999999998876 PP == domain 2 score: 2.0 bits; conditional E-value: 0.35 YabA 4 kelfdqleeleeqleellkeleelkeel 31 +el d ++ +++++e+lkel++lk+e FUN_001702-T1 513 RELEDLGKKTKKKTDEMLKELAQLKNEA 540 3444444444555555555555555543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (584 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2247 (0.0879624); expected 510.9 (0.02) Passed bias filter: 1226 (0.0479937); expected 510.9 (0.02) Passed Vit filter: 152 (0.00595028); expected 25.5 (0.001) Passed Fwd filter: 32 (0.00125269); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 20 [number of targets reported over threshold] # CPU time: 0.42u 0.43s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 5617.22 // Query: FUN_001703-T1 [L=630] Description: FUN_001703 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-10 39.7 0.2 1.4e-09 38.9 0.2 1.4 1 VWA von Willebrand factor type A domain 1.1e-06 28.5 10.3 1.4e-06 28.2 3.5 2.4 2 Ion_trans Ion transport protein ------ inclusion threshold ------ 0.015 15.1 3.5 0.015 15.1 3.5 1.5 2 YVC1_C Calcium channel YVC1-like, C-terminal Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.9 0.2 1.7e-13 1.4e-09 2 164 .. 208 375 .. 207 384 .. 0.81 Alignments for each domain: == domain 1 score: 38.9 bits; conditional E-value: 1.7e-13 VWA 2 ivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqysse...vrtefslndys.skeellsavkslkykgggttntgkalkyalenlf 93 ivfll + + + e+ f+ +k+ +k ++++ ++++ ++ + ++ + +e+ +n+ + + ++l++av++l+ + + + k l++a e +f FUN_001703-T1 208 IVFLLNATSEVAEDAFRVMKDSVKYIIRKYGNDRTEYHIV-IRHPDDcsfQSHEICFNNPHvNVKALIDAVDDLQRGDVDVPALHKDLQKASE-AF 301 9******************************555555543.4444556999999*****666******************999********99.55 PP VWA 94 kssagaRegapkvvvlltdGks..qdg..dveeaarelksagvkvfavgvgnadeee.Lekiasepdeghvftved 164 +s++ +++a+kv+v+ltd ++ d+ +v + e+k+++vkv++ ++g + + L+++ + d f+ve+ FUN_001703-T1 302 ESNKI-KSDAEKVLVILTDHRTclWDEqdQVMNQLTEVKAKQVKVITAAFGPHANLRqLKDVNGGAD-VLHFQVEE 375 55555.59***********66644442459********************98877666999877777.33355444 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.0 0.6 0.004 34 58 85 .. 166 192 .. 155 218 .. 0.74 2 ! 28.2 3.5 1.6e-10 1.4e-06 56 152 .. 505 615 .. 500 629 .. 0.79 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.004 Ion_trans 58 glkkkYlrspwnilDfvvvlpslislil 85 +l k++l + w+++D++ ++l+ +++ FUN_001703-T1 166 YL-KWFLLNIWCVFDVLFFPVLLVLFYI 192 56.89***********999888887765 PP == domain 2 score: 28.2 bits; conditional E-value: 1.6e-10 Ion_trans 56 alglkkkYlrspwnilDfvvvlpslislil............ses.....k.eslsllrvlrll.rllrllrlirrleglrtlvnslirslkslln 132 + ++ kY+++ wnilD++ +++++++++l + + +++ ++ +l + ++++++++++++++ +l+++l +l+ FUN_001703-T1 505 TVRF-SKYITDRWNILDLITLIIYFATFALrmvtlavsesvtD-NrslviAgYFYGINTMFLTLrTIGHVMETTKQIGPIQI---ALFHILSDLVT 595 5677.89***********************9999998766541.1555552344444445555546799*************...*********** PP Ion_trans 133 lllllllvlfifaiigvqlf 152 +++ ++ +++f+i+ ++ FUN_001703-T1 596 IFWQFIATILAFSIAITKVY 615 **************987776 PP >> YVC1_C Calcium channel YVC1-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.2 0.83 7.1e+03 209 219 .. 185 195 .. 165 225 .. 0.42 2 ? 15.1 3.5 1.7e-06 0.015 46 152 .. 507 615 .. 501 621 .. 0.80 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 0.83 YVC1_C 209 itvltnsfmai 219 + ++ ++ i FUN_001703-T1 185 VLLVLFYIIHI 195 21112222222 PP == domain 2 score: 15.1 bits; conditional E-value: 1.7e-06 YVC1_C 46 gfslyiasfwntfdlgilvlllihlalrlygilmp....dvrkhyvanmaydvlaadaill.fprlfsvldhyryfsplliafrymaadlvavsll 136 fs yi+ wn +dl l++ + +alr+ + + d r +a y ++++l + + v++ + + p+ ia+ ++ +dlv++ FUN_001703-T1 507 RFSKYITDRWNILDLITLIIYFATFALRMVTLAVSesvtDNRSLVIAGYFYG---INTMFLtLRTIGHVMETTKQIGPIQIALFHILSDLVTIFWQ 599 59***************************99876511114444555555554...4555550555678*************************999 PP YVC1_C 137 iliscsgffvaltlsf 152 + + f +a+t + FUN_001703-T1 600 FIATILAFSIAITKVY 615 9999999999998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (630 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1745 (0.0683108); expected 510.9 (0.02) Passed bias filter: 830 (0.0324917); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6035.99 // Query: FUN_001707-T1 [L=89] Description: FUN_001707 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (89 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1894 (0.0741437); expected 510.9 (0.02) Passed bias filter: 895 (0.0350362); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.34s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 910.38 // Query: FUN_001708-T1 [L=116] Description: FUN_001708 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 580 (0.022705); expected 510.9 (0.02) Passed bias filter: 417 (0.0163241); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.42s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1171.78 // Query: FUN_001709-T1 [L=496] Description: FUN_001709 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 5.3 6.8 21.4 6.8 6.5 21.4 1.1 1 SOG2 RAM signalling pathway protein Domain annotation for each model (and alignments): >> SOG2 RAM signalling pathway protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 21.4 0.00027 6.8 163 317 .. 49 179 .. 22 243 .. 0.38 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.00027 SOG2 163 skkkrasrtksksistssssspsssaesstrsksssvtptrrrRhagsfs.plrsdttiqlpksnlsspasngaqtstpessasssv.spssast. 255 ++ +++s+++++s+s +s +gs s p +s +t+++p+s++s+++++ + ++++++++ s+ ++++st FUN_001709-T1 49 TTYTSLSNPNATSTSHQS---------------------------NGSTSyP-TSTETTSYPTSTGSTSNPTSTGSTSYPTTTGSTSyPTTTGSTs 116 223333333333333333...........................3444322.2222222322222222222222222222222222122222222 PP SOG2 256 ..lsegstspp.galsrstlstsgsqsslsss.srsrsssrsntllststpsslattpr.pssgesf 317 ++gst+ p ++ s+s ++t+gs+s +++ s s +t sts p+ +t+ +++g++ FUN_001709-T1 117 ypTTTGSTNYPtTTGSTSYPATTGSTSYPTTTgSTSYP----TTTGSTSYPTATGSTSYpTATGSTS 179 22222222222222333333333322222111011111....1111111111111111111111111 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (496 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 805 (0.031513); expected 510.9 (0.02) Passed bias filter: 366 (0.0143277); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.41s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 4861.58 // Query: FUN_001711-T1 [L=134] Description: FUN_001711 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.4e-10 40.3 0.5 7.9e-10 39.1 0.6 1.5 2 7tm_1 7 transmembrane receptor (rhodopsin family) 0.0032 17.3 2.7 0.004 17.0 2.7 1.1 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.0092 15.5 0.8 0.01 15.4 0.8 1.1 1 7TM_GPCR_Srt Serpentine type 7TM GPCR chemoreceptor Srt Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 0.3 2.5e+03 196 213 .. 37 54 .. 10 54 .. 0.74 2 ! 39.1 0.6 9.3e-14 7.9e-10 1 65 [. 55 124 .. 55 130 .. 0.84 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.3 xxxxxxxxxxxxxxxxxx RF 7tm_1 196 rkerkalktllvvvvvfv 213 rk++k++ ++ ++v+ f+ FUN_001711-T1 37 RKTSKVTALTSIIVISFI 54 455577777777777765 PP == domain 2 score: 39.1 bits; conditional E-value: 9.3e-14 xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtpt.nifllnLavaDllvlllvlpfalvyallegdwvf....gevlCklvtald 65 gN+++++v+l++k++rt+t fl+n+a+aDl+++++++p +lv++++ +d+ + g vlCkl+ +++ FUN_001711-T1 55 GNVCIVAVTLKTKRMRTATaFKFLMNMAIADLCTTVINMPESLVTEIMDSDQWIpgtmGMVLCKLLPFCQ 124 8****************66377*************************755443234448889***99987 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 2.7 4.7e-07 0.004 6 60 .. 48 103 .. 43 125 .. 0.84 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 4.7e-07 7TM_GPCR_Srw 6 lsivgviinifHlii.LtrksmrtssinilmiGIaicDiltmlltiynkileliie 60 + ++++i n+ + + L k mrt + + +++ +ai+D++t+++++ + +++ i++ FUN_001711-T1 48 IIVISFIGNVCIVAVtLKTKRMRTATAFKFLMNMAIADLCTTVINMPESLVTEIMD 103 5688999998888775889***************************9999887776 PP >> 7TM_GPCR_Srt Serpentine type 7TM GPCR chemoreceptor Srt # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.8 1.2e-06 0.01 30 91 .. 36 102 .. 26 128 .. 0.76 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 1.2e-06 7TM_GPCR_Srt 30 krpllGilllvsGivlllLYipillvi.lkkklik.sscykimllLailDilallvn...siitGil 91 r++ ++ l+s iv+ ++ ++++++ lk+k ++ ++++k ++ +ai D++++++n s++t i+ FUN_001711-T1 36 IRKTSKVTALTSIIVISFIGNVCIVAVtLKTKRMRtATAFKFLMNMAIADLCTTVINmpeSLVTEIM 102 566677788889999999988877665267777762579****************974446766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 803 (0.0314347); expected 510.9 (0.02) Passed bias filter: 439 (0.0171854); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1395.66 // Query: FUN_001712-T1 [L=103] Description: FUN_001712 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 487 (0.0190644); expected 510.9 (0.02) Passed bias filter: 439 (0.0171854); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1061.11 // Query: FUN_001713-T1 [L=126] Description: FUN_001713 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.088 13.8 1.0 0.13 13.3 1.0 1.3 1 MRFAP1 MORF4 family-associated protein1 0.15 13.2 1.3 0.29 12.3 1.3 1.6 1 SMAP Small acidic protein family 0.43 11.2 3.8 0.61 10.7 3.8 1.2 1 Fib_alpha Fibrinogen alpha/beta chain family 3.7 7.9 6.4 0.72 10.2 0.8 2.3 2 DivIC Septum formation initiator Domain annotation for each model (and alignments): >> MRFAP1 MORF4 family-associated protein1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 1.0 2e-05 0.13 60 110 .. 73 122 .. 36 124 .. 0.83 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2e-05 MRFAP1 60 kseveaseesaldparsPgaeaeervaklcakaerkakeaarmgkrivelh 110 k +ve +e+ a a++P ea++ v +l k+ r +a++ +++ el+ FUN_001713-T1 73 KRHVE-KEKQATSIANNPLPEADKEVLRLQGKVLRLQEKIAKLQHKVAELQ 122 56676.578899***********************************9995 PP >> SMAP Small acidic protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 1.3 4.6e-05 0.29 35 66 .. 44 75 .. 16 83 .. 0.71 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 4.6e-05 SMAP 35 sakanmalskkkqeklqqdLekQyeaamkkke 66 +++ + ++ kkk+++l +Le Qy++ + k++ FUN_001713-T1 44 ERAVSNQALKKKRQTLHGNLETQYDETLTKRH 75 255666778999**************999443 PP >> Fib_alpha Fibrinogen alpha/beta chain family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 3.8 9.6e-05 0.61 32 129 .. 26 122 .. 14 123 .. 0.72 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 9.6e-05 Fib_alpha 32 evkkdiekLeneleelsnstkeakelvkaikdslrerqkskkdndnvvkkvskeleeeiaklket.vdeqesnirvLqevlesnrqkiqkLeqdid 126 + +++ ++ n++++++ + +++ k+ +++l+ + +++ d ++++k + e e++ + + ++ + e +++ Lq+ + ++++ki+kL+++++ FUN_001713-T1 26 NYEQSSKETPNNVHDVKPERAVSNQALKKKRQTLHGNLETQYD--ETLTKRHVEKEKQATSIANNpLPEADKEVLRLQGKVLRLQEKIAKLQHKVA 119 5555556667788888888888888888888888888888874..4444444444445555555415555699999*****************999 PP Fib_alpha 127 qke 129 +++ FUN_001713-T1 120 ELQ 122 876 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.5 0.11 6.9e+02 28 38 .. 47 57 .. 17 81 .. 0.68 2 ? 10.2 0.8 0.00011 0.72 23 51 .. 94 122 .. 90 125 .. 0.83 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.11 DivIC 28 eleaeiaklka 38 +++++k+++ FUN_001713-T1 47 VSNQALKKKRQ 57 44444444433 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00011 DivIC 23 kqeiaeleaeiaklkaeneeLeaeikdLk 51 ++e+ +l+ ++ +l++++++L++++++L+ FUN_001713-T1 94 DKEVLRLQGKVLRLQEKIAKLQHKVAELQ 122 68889999999999999999999999883 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2011 (0.0787238); expected 510.9 (0.02) Passed bias filter: 819 (0.0320611); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1253.16 // Query: FUN_001714-T1 [L=208] Description: FUN_001714 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 6.9 7.3 8.3 8.6 7.0 0.2 2.8 3 bHLH_INO4 INO4 bHLH domain Domain annotation for each model (and alignments): >> bHLH_INO4 INO4 bHLH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.2 0.72 1.8e+04 17 29 .. 80 92 .. 75 97 .. 0.62 2 ? 5.0 0.4 0.0014 36 11 32 .. 116 137 .. 108 151 .. 0.82 3 ? 7.0 0.2 0.00034 8.6 10 38 .. 157 185 .. 150 195 .. 0.82 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 0.72 bHLH_INO4 17 kkrreleraifde 29 k el+r + +e FUN_001714-T1 80 KEEEELQRKLVEE 92 4555666666555 PP == domain 2 score: 5.0 bits; conditional E-value: 0.0014 bHLH_INO4 11 nhvssekkrreleraifdelva 32 h ss+k +el+r + +e a FUN_001714-T1 116 KHNSSNKEEKELQRKLVEEERA 137 799************9998666 PP == domain 3 score: 7.0 bits; conditional E-value: 0.00034 bHLH_INO4 10 inhvssekkrreleraifdelvavvpdlq 38 h ss+kk el+r + ++ a d q FUN_001714-T1 157 KKHCSSNKKEEELQRKLVEKERAQAFDCQ 185 57*************99988777666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2745 (0.107457); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 89 (0.00348405); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.40 # Mc/sec: 2085.76 // Query: FUN_001715-T1 [L=641] Description: FUN_001715 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0034 17.9 1.5 2.5 8.7 0.1 3.4 3 Type_III_YscG Bacterial type III secretion system chaperone ------ inclusion threshold ------ 0.39 11.5 3.8 12 6.7 0.1 3.4 3 OMP10 Outer membrane lipoprotein Omp10 0.55 10.5 4.0 24 5.3 0.1 2.6 2 Rv3651-like_C Rv3651-like, C-terminal domain Domain annotation for each model (and alignments): >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 0.37 3.2e+03 19 37 .. 158 176 .. 156 187 .. 0.60 2 ! 6.4 0.1 0.0015 13 10 38 .. 185 213 .. 178 230 .. 0.80 3 ! 8.7 0.1 0.00029 2.5 12 56 .. 241 286 .. 231 308 .. 0.72 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.37 Type_III_YscG 19 qhcheeaniiaewlerkge 37 +h +ea +i++ l + g+ FUN_001715-T1 158 NHTGNEADCISQDLITSGN 176 5667777777766655443 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0015 Type_III_YscG 10 aeialvGsGqhcheeaniiaewlerkgee 38 + l+ G h +ean+i+ l g++ FUN_001715-T1 185 VSLDLIADGTHTGNEANCISSDLIAIGNH 213 56889**************9888766554 PP == domain 3 score: 8.7 bits; conditional E-value: 0.00029 Type_III_YscG 12 ialvGsGqhcheeaniiaewlerkgeeeaarlirlss.lanqGkyq 56 + l+ G+ +ean+i+ +l g+ + +ss l+ +G+y FUN_001715-T1 241 LDLIADGNSTGNEANCISLYLIADGNSTGNEANCISShLISNGNYT 286 6678888888888888888888887775555555544367777775 PP >> OMP10 Outer membrane lipoprotein Omp10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.1 0.0014 12 27 62 .. 168 203 .. 159 208 .. 0.88 2 ? -0.1 0.1 0.19 1.6e+03 30 62 .. 243 275 .. 229 279 .. 0.84 3 ? 3.1 0.4 0.019 1.7e+02 27 60 .. 276 309 .. 252 311 .. 0.78 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0014 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskvnCa 62 +++ +++G+Yt ++a+ v+++l ++t ++nC FUN_001715-T1 168 SQDLITSGNYTGNEANYVSLDLIADGTHTGNEANCI 203 566789*****************************6 PP == domain 2 score: -0.1 bits; conditional E-value: 0.19 OMP10 30 kLaeGtYtktsaklveieltslvrktqskvnCa 62 +a+G+ t ++a+ +++ l + t ++nC FUN_001715-T1 243 LIADGNSTGNEANCISLYLIADGNSTGNEANCI 275 679999999999999999999999999999995 PP == domain 3 score: 3.1 bits; conditional E-value: 0.019 OMP10 27 tgekLaeGtYtktsaklveieltslvrktqskvn 60 + + +++G+Yt ++ + v+++l + ++t ++n FUN_001715-T1 276 SSHLISNGNYTGNAVNYVSLDLIAIGNQTGNEAN 309 567899****************999999887776 PP >> Rv3651-like_C Rv3651-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.1 0.0028 24 22 79 .. 521 578 .. 514 587 .. 0.74 2 ? 5.1 1.3 0.0032 27 27 56 .. 588 616 .. 582 627 .. 0.80 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0028 Rv3651-like_C 22 dlkswkllkwldepcPfldwraeekeesvvhPddeaelasmaaefatGatsrvlrlra 79 d sw++ k ld+ +l+wr ++ + + + a ma+ tG+ ++ l+ FUN_001715-T1 521 DDSSWNFAKLLDHCNEYLNWRRSSDVSLRTESLLIAMEICMAVSNKTGPETKFCALKD 578 7789*****************9886666655555555556777777777766666665 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0032 Rv3651-like_C 27 kllkwldepcPfldwraeekeesvvhPdde 56 ++ kw ++ P+l+wr ++ + + +P+d+ FUN_001715-T1 588 QITKWWNNCWPYLEWRKSNVSV-QTDPQDN 616 567*************999654.5678775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (641 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 599 (0.0234488); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6309.40 // Query: FUN_001716-T1 [L=595] Description: FUN_001716 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00024 21.7 0.0 0.00047 20.7 0.0 1.4 1 SPRY SPRY domain 0.0033 17.1 0.3 0.0057 16.3 0.3 1.4 1 Ion_trans Ion transport protein 0.0063 16.7 0.7 0.014 15.5 0.7 1.5 1 Tetraspanin Tetraspanin family 0.0077 15.9 8.7 0.013 15.2 8.7 1.2 1 AIP3 Actin interacting protein 3 ------ inclusion threshold ------ 0.013 16.9 2.5 0.36 12.3 0.1 2.9 2 Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain 0.069 14.1 0.8 0.069 14.1 0.8 2.3 2 Spectrin_SESTD1 SESTD1-like, spectrin repeat 0.28 11.8 5.7 4.9 7.8 0.9 2.6 2 Sec10_N Exocyst complex component Sec10, N-terminal 0.83 8.8 10.9 1.6 7.9 10.9 1.3 1 FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and cataly 1.6 8.4 6.9 0.4 10.4 0.9 2.3 2 CorA CorA-like Mg2+ transporter protein 2.1 8.6 13.6 0.5 10.6 2.5 2.6 2 BRE1B BRE1B-like domain 2.9 9.0 9.1 1.4 10.1 2.9 2.6 2 YabA Initiation control protein YabA 3.9 8.0 15.9 0.11 12.9 3.3 2.6 2 Prefoldin_2 Prefoldin subunit 4 7.2 9.3 1.9 8.3 3.9 2.2 2 FliD_C Flagellar hook-associated protein 2 C-termin 4.3 7.8 13.0 0.53 10.8 2.5 2.6 2 Laminin_II Laminin Domain II 7.2 7.9 12.3 2.1 9.7 1.9 2.8 2 Occludin_ELL Occludin homology domain 7.6 7.1 8.5 3.3 8.3 1.1 2.7 2 DUF1664 Protein of unknown function (DUF1664) 8.1 7.2 15.2 4.2 8.1 2.9 2.6 2 Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 9.9 6.8 9.5 10 6.8 4.8 2.5 2 Fib_alpha Fibrinogen alpha/beta chain family Domain annotation for each model (and alignments): >> SPRY SPRY domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 3.3e-07 0.00047 4 88 .. 251 343 .. 249 377 .. 0.77 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 3.3e-07 SPRY 4 feveve.gqekgsvrvGvatksvprkgekflgdeegswgydgwkgkky...sastsestglplfeegdviGcflDleeg.....eisFtkngks 88 fev ++ +++ + +G + k + ++ ++g+ +g +gy+ ++gk++ + ++++ ++ + gd iGc + +e + Ft ng++ FUN_001716-T1 251 FEVLIQeTGDRRFLGIGAVWKGYG-ASHSMPGWSKGTVGYHVDDGKIFdakNPHKGKEVEDAMAYRGDLIGCTIKFEGItngqvPVVFTLNGRP 343 999999999999999********9.9999******************988888888888888999**********9965333444777777744 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.3 4e-06 0.0057 206 241 .. 18 53 .. 6 55 .. 0.86 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 4e-06 Ion_trans 206 aiaviyfvlfiilggvlllnlliaviidnfqelter 241 ++ ++++ f+++g++ll+n++ia++++++q+++++ FUN_001716-T1 18 MLVHFLYGAFLVMGAILLINMMIALLSNTYQKVQDN 53 5667899*************************9976 PP >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.7 9.9e-06 0.014 76 153 .. 21 102 .. 14 123 .. 0.67 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 9.9e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxx.xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxx....x RF Tetraspanin 76 lllyfvlllllflaelaagilafvyrdk..ekeelsnw.lkksledsyedasdlkskke..ealdslqeelkCCGvnsysDw....e 153 +ly +l++ ++++ + i+++ ++ + ++++l +w +kk++ ++++s+++ ++++ lkCCG+++ +w + FUN_001716-T1 21 HFLYGAFLVMGAILLINMMIALLSNTYQkvQDNSLMEWsFKKAIT-----IQTYSSCDPipVPVNFVFLMLKCCGWQKCFNWcrnrK 102 467778888888888888886666666633444445554555552.....233344444779999999999***********43220 PP >> AIP3 Actin interacting protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 8.7 9.1e-06 0.013 64 189 .. 408 570 .. 402 574 .. 0.83 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 9.1e-06 AIP3 64 rsvLsLniekldevkkhideslasllkelkelkssiesqkasaqevserqeeaakekaeesla................................. 126 + v+ + + ++e+k+ +d ++++l+ke++e+++++++ k+++q ++++ +++ k+ ++ + FUN_001716-T1 408 QLVIAMALNDVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLSNSFKRVKKMFFLddrprnnvlqaamecaastvsqldrrlimtwes 503 5678888999*******************************999999988888888877444499*****************************88 PP AIP3 127 .....kkdlkaqlkevqslrrdLavlrqlysefkseikesiselrekakkvkeaslastkkssnrayi 189 +++ ++ ++ +rr+L+ l + +e+++e+ +++++l++ a+ +++ sl+s++++ +++++ FUN_001716-T1 504 qaeekERKVPIIVDLLRMIRRELEGLGKKTKEKTDEMLKELAQLKTDAQ-LQHRSLKSKNEGLDKKFL 570 8776555566667788888999999988888888889899999888876.444677777777777665 PP >> Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.2 0.14 2e+02 35 74 .. 419 459 .. 403 470 .. 0.67 2 ? 12.3 0.1 0.00025 0.36 29 73 .. 532 577 .. 500 579 .. 0.83 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.14 Myb_DNA-bind_3 35 keileefna.ktgakytkeqlknrlkklrkqyklvkellee 74 kei e++ a +++k++ ++++n+lk+++++ ++ ++ l++ FUN_001716-T1 419 KEIKETVDAnCKRLKKEVQEIRNHLKNAKEESQALENTLSN 459 55555555555556777777777777777776666665543 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00025 Myb_DNA-bind_3 29 fkkeawkeileefna.ktgakytkeqlknrlkklrkqyklvkelle 73 +ke+ +e+l+e+ + kt+a+ +++ lk++ + l k++ ++el++ FUN_001716-T1 532 KTKEKTDEMLKELAQlKTDAQLQHRSLKSKNEGLDKKFLEIEELIQ 577 468889********************************99999876 PP >> Spectrin_SESTD1 SESTD1-like, spectrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.8 4.9e-05 0.069 14 73 .. 399 462 .. 387 486 .. 0.83 2 ? -1.4 0.4 3.1 4.4e+03 14 60 .. 534 550 .. 521 581 .. 0.51 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 4.9e-05 Spectrin_SESTD1 14 sqklDgLLellctdvkaedvasiek....elkeLeekveevekaleslrekGqslldelseqek 73 s+ D Le l++ ++++dv++i++ + k L++ v+e+ + l++++e++q+l + ls+ k FUN_001716-T1 399 SRDSDLELEQLVIAMALNDVKEIKEtvdaNCKRLKKEVQEIRNHLKNAKEESQALENTLSNSFK 462 556677799**********99765411117899***********************99998765 PP == domain 2 score: -1.4 bits; conditional E-value: 3.1 Spectrin_SESTD1 14 sqklDgLLellctdvkaedvasiekelkeLeekveevekaleslrek 60 +k+D++L+ l +l+++ FUN_001716-T1 534 KEKTDEMLKELA------------------------------QLKTD 550 344555544443..............................22222 PP >> Sec10_N Exocyst complex component Sec10, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.9 0.0034 4.9 11 66 .. 414 458 .. 405 496 .. 0.66 2 ? 5.9 0.3 0.013 19 12 66 .. 523 577 .. 513 592 .. 0.82 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0034 Sec10_N 11 alkeLkeLqeqvqekeqklekavrqaeakhskklneLskkldqivdsfqqLdekis 66 al+++ke++e v++++++l+k+v++ ++ l+++ ++ q+L++++s FUN_001716-T1 414 ALNDVKEIKETVDANCKRLKKEVQEI-----------RNHLKNAKEESQALENTLS 458 56666666666666666666666544...........3333333333333333333 PP == domain 2 score: 5.9 bits; conditional E-value: 0.013 Sec10_N 12 lkeLkeLqeqvqekeqklekavrqaeakhskklneLskkldqivdsfqqLdekis 66 +eL+ L ++++ek++++ k+++q + + + + + L++k++ + ++f +++e i+ FUN_001716-T1 523 RRELEGLGKKTKEKTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEIEELIQ 577 4699999999999999999999999888888888888888888888888887776 PP >> FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalytic domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 10.9 0.0011 1.6 25 173 .. 415 566 .. 404 575 .. 0.73 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0011 FUT8_N_cat 25 vlssklleknaeee.eesskrleevlekleelkkqneelkellekrleeseeekk.kaeeklksleeklekakekleeakkskknelsleyEvlrr 118 + k ++++++++ ++ +k+++e+ ++l++ k+++++l++ l++ ++ ++ + +++ l++ +e a +++++ ++ + + + E+ r FUN_001716-T1 415 LNDVKEIKETVDANcKRLKKEVQEIRNHLKNAKEESQALENTLSNSFKRVKKMFFlDDRPRNNVLQAAMECAASTVSQLDRRLIMTWESQAEEKER 510 33334444444444588899*********************9999777766654422333566667777777778888888888889999999999 PP FUT8_N_cat 119 rleneikElwyllsselkklkkeekee..elekeieellellaeqkrslladiekle 173 ++ i +l +++ el+ l k++ke+ e+ ke+ +l + ++ q+rsl ++ e l+ FUN_001716-T1 511 KVP-IIVDLLRMIRRELEGLGKKTKEKtdEMLKELAQLKTDAQLQHRSLKSKNEGLD 566 996.5889************9998888556666666666666667788887777665 PP >> CorA CorA-like Mg2+ transporter protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.6 0.29 4.1e+02 181 224 .. 416 459 .. 385 467 .. 0.63 2 ? 10.4 0.9 0.00028 0.4 123 174 .. 515 565 .. 509 576 .. 0.90 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.29 CorA 181 eddgqlddeqkeylrdlldrlerlleeldalrerleslqdeyss 224 +d +++++ + ++++l +++++ ++l+ e+ ++l +++s+ FUN_001716-T1 416 NDVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLSN 459 55555555555556666666666666666666666666666555 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00028 CorA 123 leellekleeeleeledeledeednellrelaalrrsliklrrallpqrevl 174 + +ll+ +++ele l ++ +e+++e+l ela+l++++ +r+l+++ e l FUN_001716-T1 515 IVDLLRMIRRELEGLGKKT-KEKTDEMLKELAQLKTDAQLQHRSLKSKNEGL 565 57899**************.99***********************9988766 PP >> BRE1B BRE1B-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 2.5 0.00035 0.5 103 147 .. 416 460 .. 407 464 .. 0.86 2 ? 3.5 2.5 0.056 80 93 138 .. 532 577 .. 515 584 .. 0.79 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00035 BRE1B 103 kEmrhLinsLqnhnkqlkgevqRykrklkelqeelaklkkeleee 147 ++++++ +++ ++k+lk+evq +++ lk+++ee + l+++l+++ FUN_001716-T1 416 NDVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLSNS 460 5788888999999**********************9999988766 PP == domain 2 score: 3.5 bits; conditional E-value: 0.056 BRE1B 93 aaneqagpinkEmrhLinsLqnhnkqlkgevqRykrklkelqeela 138 +++e++ + kE+ +L + q + ++lk+ ++ + +k+ e++e ++ FUN_001716-T1 532 KTKEKTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEIEELIQ 577 5788899999999999999999999999999988888888887766 PP >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 2.9 0.00095 1.4 22 77 .. 413 468 .. 394 469 .. 0.79 2 ? 1.7 0.4 0.4 5.7e+02 12 45 .. 532 562 .. 515 580 .. 0.55 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00095 YabA 22 keleelkeelaelleenaeLeiEnekLrerlkkeeekekekkkelsegkenLaklY 77 l+++ke +++ + ++L+ E +++r++lk+++e++++ +++ls++ + ++k++ FUN_001716-T1 413 MALNDVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLSNSFKRVKKMF 468 4455666555555556689*************999999*99*****9999999886 PP == domain 2 score: 1.7 bits; conditional E-value: 0.4 YabA 12 eleeqleellkeleelkeelaelleenaeLeiEn 45 + +e+++e+lkel++lk++ + ++++L+ n FUN_001716-T1 532 KTKEKTDEMLKELAQLKTDAQ---LQHRSLKSKN 562 344555555555555555433...1223333333 PP >> Prefoldin_2 Prefoldin subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 3.3 8.1e-05 0.11 56 104 .. 414 462 .. 411 463 .. 0.85 2 ? -0.1 4.8 0.92 1.3e+03 57 99 .. 534 576 .. 531 579 .. 0.83 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 8.1e-05 Prefoldin_2 56 vkqdkeevkeeLeerketlekeiktlekqleklekeleelkeelqkklq 104 ++d++e+ke+++++ ++l+ke++++ + l++ ++e + l+++l + ++ FUN_001716-T1 414 ALNDVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLSNSFK 462 5689999999999999999999999999999999999999999887765 PP == domain 2 score: -0.1 bits; conditional E-value: 0.92 Prefoldin_2 57 kqdkeevkeeLeerketlekeiktlekqleklekeleelkeel 99 k++ +e+ +eL + k +++ + ++l+++ e l k++ e++e + FUN_001716-T1 534 KEKTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEIEELI 576 5677888999999999999999999999999999999988766 PP >> FliD_C Flagellar hook-associated protein 2 C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 1.5 0.016 22 184 235 .. 422 466 .. 405 473 .. 0.63 2 ? 8.3 3.9 0.0014 1.9 144 238 .. 451 577 .. 449 579 .. 0.89 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.016 FliD_C 184 ksyvkasngtlatrskslnkqiksldkqiedldkrleklearlkaqfsaldk 235 k +t++++ k+l+k+++++ + ++++++++++le++l + f++ k FUN_001716-T1 422 K-------ETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLSNSFKRVKK 466 3.......55556666666666666666666666666666666666665444 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0014 FliD_C 144 ekLkkalkenpdsvrelFtgd...............................gskderv.dtGlakrledllksyvkasngtlatrskslnkqiks 207 + L+++l+++++ v+++F d ++ +e++ + ++ +l ++++ +++ +++++++++++ k++++ FUN_001716-T1 451 QALENTLSNSFKRVKKMFFLDdrprnnvlqaamecaastvsqldrrlimtweSQAEEKErKVPIIVDLLRMIRRELEGLGKKTKEKTDEMLKELAQ 546 679999**********99988899999999999999999999999999998644444446999*************9999**************** PP FliD_C 208 ldkqiedldkrleklearlkaqfsaldklvs 238 l+++ + ++l+++++ l ++f ++++l++ FUN_001716-T1 547 LKTDAQLQHRSLKSKNEGLDKKFLEIEELIQ 577 **************************99986 PP >> Laminin_II Laminin Domain II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 2.5 0.00037 0.53 45 98 .. 413 467 .. 386 494 .. 0.85 2 ? 4.2 0.6 0.041 58 29 82 .. 522 576 .. 498 585 .. 0.73 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00037 Laminin_II 45 ekvkdankalrdArrsvkkLeklapqLldklkelkqleeasss.lsdniseikel 98 ++d +++ + + + k L+k+++++ + lk+ k+ ++a ++ ls++ +++k++ FUN_001716-T1 413 MALNDVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENtLSNSFKRVKKM 467 4567888888899999999999999999999999999999999999999999998 PP == domain 2 score: 4.2 bits; conditional E-value: 0.041 Laminin_II 29 tkeklseinrsv.eetnekvkdankalrdArrsvkkLeklapqLldklkelkqle 82 ++ +l+++ ++ e+t+e +k++ + dA+ + + L+ + + L +k+ e+++l FUN_001716-T1 522 IRRELEGLGKKTkEKTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEIEELI 576 4555555544431578888889999999999999999999999999998888875 PP >> Occludin_ELL Occludin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 1.9 0.0015 2.1 25 96 .. 419 490 .. 413 495 .. 0.77 2 ? 2.3 3.3 0.28 4e+02 46 97 .. 524 577 .. 480 578 .. 0.78 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.0015 Occludin_ELL 25 keLhaeleavskkfskleeelks.lkegskeykkiaeeilqeykklkkdpeylekkkrceyLkekLshiKkli 96 ke++++++a k+++k +e+++ lk+ ++e + +++ + +++k++ k+ +l+++ r ++L++ +++ + + FUN_001716-T1 419 KEIKETVDANCKRLKKEVQEIRNhLKNAKEESQALENTLSNSFKRV-KKMFFLDDRPRNNVLQAAMECAASTV 490 78999999999999876666655055555599999999999***99.67889999999999998777655555 PP == domain 2 score: 2.3 bits; conditional E-value: 0.28 Occludin_ELL 46 kslkegskeykkiaeeilqeykklkk..dpeylekkkrceyLkekLshiKklik 97 ++l+ k+ k+ ++e+l+e+ +lk+ + ++++ k++ e L +k i +li+ FUN_001716-T1 524 RELEGLGKKTKEKTDEMLKELAQLKTdaQLQHRSLKSKNEGLDKKFLEIEELIQ 577 334444456777778888888888884456788899999999999999999886 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 1.1 0.0023 3.3 70 111 .. 417 458 .. 402 468 .. 0.52 2 ? 2.1 0.8 0.19 2.7e+02 42 82 .. 536 576 .. 515 581 .. 0.71 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0023 DUF1664 70 rvdkkldeqkeiskeikeevtevredvsnikedvksvkeave 111 v++ + + + k++k+ev e+r++++n ke++++++++++ FUN_001716-T1 417 DVKEIKETVDANCKRLKKEVQEIRNHLKNAKEESQALENTLS 458 333333333334444445555555555555555555544444 PP == domain 2 score: 2.1 bits; conditional E-value: 0.19 DUF1664 42 avesvskqleqvseslaatKkeLsqridrvdkkldeqkeis 82 +++ k+l q+++ + + + L+++ + +dkk e +e++ FUN_001716-T1 536 KTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEIEELI 576 45566677777777777777777777777777777776665 PP >> Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 2.9 0.003 4.2 57 99 .. 419 459 .. 410 466 .. 0.75 2 ? 4.0 4.6 0.057 81 60 104 .. 530 572 .. 503 576 .. 0.75 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.003 Seryl_tRNA_N 57 keIgkakkkkedaeeliaevkelkeelkaleeelkeleaelek 99 keI++ ++ + ++l++ev+e+ + lk+++ee ++le+ l + FUN_001716-T1 419 KEIKETVDA--NCKRLKKEVQEIRNHLKNAKEESQALENTLSN 459 455555544..57788888888888888888888888888765 PP == domain 2 score: 4.0 bits; conditional E-value: 0.057 Seryl_tRNA_N 60 gkakkkkedaeeliaevkelkeelkaleeelkeleaeleklllai 104 g kk ke+++e+++e ++lk++ + lk ++ l+k+ l+i FUN_001716-T1 530 G--KKTKEKTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEI 572 3..4555779****************************9999988 PP >> Fib_alpha Fibrinogen alpha/beta chain family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 4.8 0.0071 10 22 73 .. 421 465 .. 413 538 .. 0.55 2 ? 1.6 0.7 0.29 4.1e+02 40 97 .. 522 576 .. 497 584 .. 0.60 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0071 Fib_alpha 22 lqdlllkqekevkkdiekLeneleelsnstkeakelvkaikdslrerqkskk 73 ++++++ + k +kk++++++n+l++++ e ++a++++l + k k FUN_001716-T1 421 IKETVDANCKRLKKEVQEIRNHLKNAK-------EESQALENTLSNSFKRVK 465 444455555555555555555555555.......555555544444444333 PP == domain 2 score: 1.6 bits; conditional E-value: 0.29 Fib_alpha 40 Leneleelsnstkeakelvkaikdslrerqkskkdndnvvkkvskeleeeiaklketv 97 +++ele l k++ke + ++ + l++ +++++ + + +k ++ l+++ ++++e + FUN_001716-T1 522 IRRELEGL---GKKTKEKTDEMLKELAQLKTDAQLQHRSLKSKNEGLDKKFLEIEELI 576 33333333...34444444444444544444444455677777888888888888777 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (595 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2552 (0.0999021); expected 510.9 (0.02) Passed bias filter: 1202 (0.0470542); expected 510.9 (0.02) Passed Vit filter: 148 (0.0057937); expected 25.5 (0.001) Passed Fwd filter: 31 (0.00121354); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.44u 0.45s 00:00:00.89 Elapsed: 00:00:00.43 # Mc/sec: 5586.06 // Query: FUN_001717-T1 [L=419] Description: FUN_001717 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-10 40.8 0.2 5.7e-10 40.2 0.2 1.2 1 VWA von Willebrand factor type A domain 8.9e-06 25.5 4.8 8.9e-06 25.5 4.8 1.7 2 Ion_trans Ion transport protein 0.007 16.2 4.3 0.013 15.3 4.3 1.4 1 YVC1_C Calcium channel YVC1-like, C-terminal ------ inclusion threshold ------ 0.08 13.5 0.1 0.22 12.1 0.1 1.7 1 Staphostatin_B Staphostatin B 1.8 9.8 4.4 3 9.2 1.3 2.6 2 M M protein repeat Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.2 0.2 1.1e-13 5.7e-10 2 164 .. 5 172 .. 4 181 .. 0.81 Alignments for each domain: == domain 1 score: 40.2 bits; conditional E-value: 1.1e-13 VWA 2 ivfllDgSgsigeenfekvkeflkklvesldigpdstrvglvqysse...vrtefslndys.skeellsavkslkykgggttntgkalkyalenlf 93 ivfll + + + ++ f+ +ke +k ++++ ++ + ++ + ++ + +e+ +n+ + + ++l++av++l+ + + + k l++a e +f FUN_001717-T1 5 IVFLLNATSEVAQDAFHIMKESVKYIIRKYGNDRAEYHIV-IRHPDDcsfQSHEICFNNPHvNVKALIDAVEDLQRGDADVPALHKDLQKANE-AF 98 9******************************666666554.4444556999999*****666************999999999******9988.55 PP VWA 94 kssagaRegapkvvvlltdGks..qdg..dveeaarelksagvkvfavgvgnadeee.Lekiasepdeghvftved 164 +ss+ +++a+kv+v+ltd ++ d+ +v + e+k+++vkv++ ++g + + L+++ + d f+ve+ FUN_001717-T1 99 ESSKI-KSDAEKVLVILTDHRTclWDEqdQVMNQLTEVKAKQVKVITAAFGPHANLRqLKDVNGGAD-VLHFQVEE 172 55555.59***********66644442459********************98877766999977777.33344444 PP >> Ion_trans Ion transport protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.1 0.32 1.6e+03 36 45 .. 226 235 .. 179 266 .. 0.61 2 ! 25.5 4.8 1.8e-09 8.9e-06 56 152 .. 294 404 .. 290 417 .. 0.80 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.32 Ion_trans 36 eildlvftvi 45 ++++++++v+ FUN_001717-T1 226 TWIEWAILVF 235 2222222222 PP == domain 2 score: 25.5 bits; conditional E-value: 1.8e-09 Ion_trans 56 alglkkkYlrspwnilDfvvvlpslislil............ses.....k.eslsllrvlrll.rllrllrlirrleglrtlvnslirslkslln 132 + ++ kY+ + wnilD++ +++++++++l + + +++ ++ +l + ++++++++++++++ +l+++l++l+ FUN_001717-T1 294 TVRF-SKYIVDRWNILDLITLIIYFATFALrmvtlavsesvtD-NrylviAgYFYGINTMFLTLrAIGHVMETTKQIGPIQI---ALFHILGDLVT 384 5677.89***********************9999988765541.1555542344455555555546789*************...*********** PP Ion_trans 133 lllllllvlfifaiigvqlf 152 +++ ++ +++f+i+ ++ FUN_001717-T1 385 IFWQFIATILAFSIAITKVY 404 *************9987666 PP >> YVC1_C Calcium channel YVC1-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 4.3 2.6e-06 0.013 46 152 .. 296 404 .. 286 411 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.6e-06 YVC1_C 46 gfslyiasfwntfdlgilvlllihlalrlygilmpd.v.rkhyvanmaydvlaadaillfprlfsvldhyryfsplliafrymaadlvavsllili 139 fs yi wn +dl l++ + +alr+ + + + v ++y+ y l + + v++ + + p+ ia+ ++ dlv++ + FUN_001717-T1 296 RFSKYIVDRWNILDLITLIIYFATFALRMVTLAVSEsVtDNRYLVIAGYFYGINTMFLTLRAIGHVMETTKQIGPIQIALFHILGDLVTIFWQFIA 391 59***************************999876523134566555555545555666667789*************************999999 PP YVC1_C 140 scsgffvaltlsf 152 + f +a+t + FUN_001717-T1 392 TILAFSIAITKVY 404 9999999998665 PP >> Staphostatin_B Staphostatin B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 4.2e-05 0.22 15 63 .. 20 67 .. 6 83 .. 0.83 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 4.2e-05 Staphostatin_B 15 thleqtninlfignwsnhqlqksicirhgddtshnqyhilfidtahqri 63 h+ + ++ +i ++ n + + i+irh dd s + + i f h + FUN_001717-T1 20 FHIMKESVKYIIRKYGNDRAEYHIVIRHPDDCSFQSHEICFN-NPHVNV 67 5888899999***********************988888874.455555 PP >> M M protein repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.38 2e+03 5 15 .. 86 96 .. 86 98 .. 0.87 2 ? 9.2 1.3 0.00058 3 3 21 .] 276 294 .. 274 294 .. 0.93 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.38 M 5 eLEaelqeLee 15 +L+++lq+++e FUN_001717-T1 86 ALHKDLQKANE 96 5899****997 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00058 M 3 kkeLEaelqeLeeelqaLe 21 k+++E+++qeL +++q L+ FUN_001717-T1 276 KEDVETKNQELGTKQQSLT 294 899*************995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (419 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1787 (0.069955); expected 510.9 (0.02) Passed bias filter: 915 (0.0358191); expected 510.9 (0.02) Passed Vit filter: 72 (0.00281856); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4056.10 // Query: FUN_001718-T1 [L=187] Description: FUN_001718 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 955 (0.037385); expected 510.9 (0.02) Passed bias filter: 671 (0.0262674); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1876.75 // Query: FUN_001719-T1 [L=102] Description: FUN_001719 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 13.3 0.8 0.15 13.0 0.8 1.0 1 STT3-PglB_core STT3/PglB/AglB core domain Domain annotation for each model (and alignments): >> STT3-PglB_core STT3/PglB/AglB core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.8 6e-06 0.15 36 118 .. 5 88 .. 2 91 .. 0.75 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 6e-06 STT3-PglB_core 36 flvsfaltkdqesaanlarlsveyteksfeekeekklkk....ilkdykkkdvnkflesLeekklklpakktrdiylylpkrmleil 118 f+ + ++++esa nl ls + +++ + ++e++k+ + ++ ++ dv+++ ++L+ + l+ kt +y+ + +i+ FUN_001719-T1 5 FMRDVKTMEESESAINLQELSNDNQDEAKAKEEKEKQ-DfeksLMDTIERGDVEEITDRLNPRALTK--CKTNTLYMAMKVDAYDIY 88 5666667788999*******99966555444433333.22446999999************888666..59*****99998888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2701 (0.105735); expected 510.9 (0.02) Passed bias filter: 1174 (0.0459581); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 993.55 // Query: FUN_001720-T1 [L=436] Description: FUN_001720 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-52 176.9 21.0 9.6e-52 176.5 21.0 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) ------ inclusion threshold ------ 0.01 16.0 0.0 0.21 11.8 0.0 2.4 2 Ilm1 Increased loss of mitochondrial DNA protein 1 0.09 13.0 13.8 0.71 10.1 13.8 2.2 1 7tm_4 Olfactory receptor Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.5 21.0 1.1e-55 9.6e-52 1 260 [] 75 338 .. 75 338 .. 0.91 Alignments for each domain: == domain 1 score: 176.5 bits; conditional E-value: 1.1e-55 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyal.legdwvf...gevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+lVi+v rn++lrt ++ f++n+a+aDl+++++++p +++ ++ +++w g v+Ck++ +l+ v+ ++s+l+l+ais+DRY aI+ p+k FUN_001720-T1 75 GNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESVIVEIrNTDQWFPgevGVVMCKFWPFLQQVCAFCSVLSLLAISLDRYFAICLPFK 170 8*****************************************9999555666544446788*********************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpe..eestwevsytlllsvlgfllpllvilvcyvrilrtlrksakk 186 + i+++++ +vlil++W+l +++s p+++ ++ + +e Cl +p+ + ++++ yt++l++l+++ pl+vi+++y++++ ++++++ FUN_001720-T1 171 R--IMSQKLSRVLILLTWLLPVVASAPMFVANNVVEI---IGELLCLEAWPSpfDPVKAPADYTIILFALFYVFPLTVISFLYSLVIFKIWRRRVP 261 9..***************************8888777...9***********655556************************************99 PP xxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 187 eks...kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ + + +r++rkalk+ + vvv f++cwlPy+++++l+s+++ + l++ + i+++++++ s++NP iY FUN_001720-T1 262 GNRstvTTEAYSRSRRKALKVFISVVVCFAFCWLPYHVTFFLMSYNEIYFYCGLPRDIAFIAVFFSHAISAFNPYIY 338 9985553333345566*****************************88888999999999****************** PP >> Ilm1 Increased loss of mitochondrial DNA protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.3 0.034 2.9e+02 64 90 .. 98 134 .. 53 185 .. 0.66 2 ? 11.8 0.0 2.5e-05 0.21 25 90 .. 195 289 .. 170 343 .. 0.77 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.034 Ilm1 64 allglsDLvll..slneeialleywgsq........a 90 + +++ DL+++ +++e + + + + q + FUN_001720-T1 98 INMAIADLMTTviNMPESVIVEIRNTDQwfpgevgvV 134 4578999987766888888443333333555555550 PP == domain 2 score: 11.8 bits; conditional E-value: 2.5e-05 Ilm1 25 peviadqdlvfvlgeamklpaars.fskpssalaflavlLallglsDLvllslneeialleywgsq.............................a 90 p +a ++v ++ge + l+a +s f+ +++ + +l+al+ ++ L+++s + + ++w+++ FUN_001720-T1 195 PMFVA-NNVVEIIGELLCLEAWPSpFDPVKAPADYTIILFALFYVFPLTVISFLYSLVIFKIWRRRvpgnrstvtteaysrsrrkalkvfisvvvC 289 44444.589***********99765888899999***********************9*******9778888888877777777555544433330 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 13.8 8.4e-05 0.71 2 116 .. 66 183 .. 65 355 .. 0.71 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 8.4e-05 7tm_4 2 clvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdar......eisfeacllqlffihkfsllesavllamavd 91 ++ + +l+Gn+ ++ v + ++ l y f+ +a++dl ++ +P+ + + + ++ e+ c + f+ ++ +lla+++d FUN_001720-T1 66 IVIIIASLVGNILVITVSRRNRNLRTIAYSFVINMAIADLMTTVINMPESVIVE-IRNTdqwfpgEVGVVMCKFWPFLQQVCAFCSVLSLLAISLD 160 5677889*****************************************976443.333312233367777788888877788899999******** PP 7tm_4 92 rfvaiysplryteiltnkvisrigl 116 r+ ai+ p++ i+++k ++ l FUN_001720-T1 161 RYFAICLPFKR--IMSQKLSRVLIL 183 ******99874..555553333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (436 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 975 (0.0381679); expected 510.9 (0.02) Passed bias filter: 443 (0.0173419); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4264.51 // Query: FUN_001721-T1 [L=132] Description: FUN_001721 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-10 39.5 0.5 8.3e-10 39.1 0.5 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.0019 18.0 2.6 0.0023 17.8 2.6 1.1 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.0094 15.9 0.7 0.012 15.5 0.7 1.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx ------ inclusion threshold ------ 0.015 14.8 1.1 0.017 14.6 1.1 1.1 1 7TM_GPCR_Srt Serpentine type 7TM GPCR chemoreceptor Srt 0.14 12.7 1.1 7 7.2 0.4 2.2 2 AlphaC_N2 AlphaC N-terminal domain 2 Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 0.5 1.6e-13 8.3e-10 1 65 [. 53 122 .. 53 128 .. 0.84 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 1.6e-13 xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtpt.nifllnLavaDllvlllvlpfalvyallegdwvf....gevlCklvtald 65 gN+++++v+l++k++rt+t fl+n+a+aDl+++++++p +lv++++ +d+ + g vlCkl+ +++ FUN_001721-T1 53 GNVCIVAVTLKTKRMRTATaFKFLINMAIADLCTTVINMPESLVTEIMDSDQWIpgtmGMVLCKLLPFCQ 122 8****************66377*************************755443234448889***99987 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 2.6 4.5e-07 0.0023 6 60 .. 46 101 .. 41 123 .. 0.84 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 4.5e-07 7TM_GPCR_Srw 6 lsivgviinifHlii.LtrksmrtssinilmiGIaicDiltmlltiynkileliie 60 + ++++i n+ + + L k mrt + + ++i +ai+D++t+++++ + +++ i++ FUN_001721-T1 46 IMVISLIGNVCIVAVtLKTKRMRTATAFKFLINMAIADLCTTVINMPESLVTEIMD 101 6788888898887765889***************************9999887776 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.7 2.3e-06 0.012 1 44 [. 47 91 .. 47 103 .. 0.75 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 2.3e-06 7TM_GPCR_Srsx 1 lvvGliGNvllilltfkkkkLrskssiLicv.qcladllclvgel 44 +v++liGNv ++ +t+k+k++r+ ++ + ++adl v ++ FUN_001721-T1 47 MVISLIGNVCIVAVTLKTKRMRTATAFKFLInMAIADLCTTVINM 91 69********************98875333314677766665555 PP >> 7TM_GPCR_Srt Serpentine type 7TM GPCR chemoreceptor Srt # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 1.1 3.3e-06 0.017 29 91 .. 33 100 .. 24 126 .. 0.76 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.3e-06 7TM_GPCR_Srt 29 vkrpllGilllvsGivlllLYipillvi.lkkklik.sscykimllLailDilallvn...siitGil 91 r++ ++ l+s +v+ l+ ++++++ lk+k ++ ++++k ++ +ai D++++++n s++t i+ FUN_001721-T1 33 IIRKISKVTALTSIMVISLIGNVCIVAVtLKTKRMRtATAFKFLINMAIADLCTTVINmpeSLVTEIM 100 5567777888888888988877777655267777762579****************974446776665 PP >> AlphaC_N2 AlphaC N-terminal domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.4 0.0014 7 26 61 .. 12 48 .. 2 53 .. 0.76 2 ? 4.1 0.0 0.013 66 45 69 .. 80 104 .. 68 105 .. 0.91 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0014 AlphaC_N2 26 lislddikt.didnnpktqsdiankitevtnlekilv 61 + ddi d + p + +i ki++vt l i+v FUN_001721-T1 12 FTDQDDIAGsDDECLPLGEKNIIRKISKVTALTSIMV 48 55668887514555799999***************98 PP == domain 2 score: 4.1 bits; conditional E-value: 0.013 AlphaC_N2 45 diankitevtnlekilvpripdadk 69 ia+ t v n+ lv i d+d+ FUN_001721-T1 80 AIADLCTTVINMPESLVTEIMDSDQ 104 589999****************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1147 (0.0449012); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1308.05 // Query: FUN_001722-T1 [L=128] Description: FUN_001722 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-08 34.1 0.6 3.4e-08 33.8 0.6 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.0014 18.6 0.8 0.0016 18.3 0.8 1.1 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.002 17.9 0.1 0.0022 17.8 0.1 1.0 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw ------ inclusion threshold ------ 0.048 14.2 0.2 0.064 13.8 0.2 1.1 1 DUF6632 Family of unknown function (DUF6632) 0.097 13.3 0.3 0.15 12.7 0.3 1.3 1 DUF4519 Domain of unknown function (DUF4519) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.8 0.6 6.7e-12 3.4e-08 187 260 .] 9 84 .. 2 84 .. 0.79 Alignments for each domain: == domain 1 score: 33.8 bits; conditional E-value: 6.7e-12 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx.xxxxxxxxxxxxxx RF 7tm_1 187 ekskkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetal.litl.llayvnsclNPiiY 260 ++++++k++ ++rk+lk +++vv+vf+ c++P+ + +l+ +++e + +++++ +++ ++ ++n+++ P iY FUN_001722-T1 9 SNRERQKREYENRKVLKQVVTVVAVFISCIFPVTVYGCLSNFVWELKPPAHIDWFTfKFCAfFILHSNAAITPCIY 84 3334455556677*****************************88888877777776566651567899*******9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.8 3.2e-07 0.0016 173 257 .] 11 99 .. 6 99 .. 0.79 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 3.2e-07 7TM_GPCR_Srsx 173 kkkekkkssskkvlkslkvtvvififgWftstilntvl...lalteseevekliqayagilvlls.fsqnffVtywrsseYrkafrell 257 ++++k++ + +kvlk + ++v +fi + f +t+ + ++ +l+ ++ + ++ +++++l s ++ + ++ + +++Yr+ + e++ FUN_001722-T1 11 RERQKREYENRKVLKQVVTVVAVFISCIFPVTVYGCLSnfvWELKPPAHIDWFTFKFCAFFILHSnAAITPCIYFIFNKNYRRGLNEMF 99 4567788999*****************99999877665111555566677778999999998876156788999999******999886 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 4.4e-07 0.0022 226 318 .. 8 101 .. 1 102 [. 0.83 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 4.4e-07 7TM_GPCR_Srw 226 rkklskskkneksdkttkLVlfmTisffiaelplGiiyivkfi.fskssgirsileelevifsllltinsisHflicllmSsqYRktvkklfgc 318 r++ ++k++ +++k k V+ + +f+ +p ++ +++ + ++ ++ ++++ + ++l n+++ i++++ +YR+ +++f c FUN_001722-T1 8 RSNRERQKREYENRKVLKQVVTVVAVFISCIFPVTVYGCLSNFvWELKPPAHIDWFTFKFCAFFILHSNAAITPCIYFIFNKNYRRGLNEMFHC 101 56666666667888999999999999999999999988875553888888888888899999999999************************99 PP >> DUF6632 Family of unknown function (DUF6632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.2 1.2e-05 0.064 5 51 .. 22 69 .. 19 87 .. 0.83 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.2e-05 DUF6632 5 kllqlalvvvgvlalllyplavv.wpsgwawhsgapyqsdyfmmivgv 51 k+l+ ++vv v + +++p++v s ++w +p + d+f + FUN_001722-T1 22 KVLKQVVTVVAVFISCIFPVTVYgCLSNFVWELKPPAHIDWFTFKFCA 69 78889999*************9734699**************876544 PP >> DUF4519 Domain of unknown function (DUF4519) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.3 3e-05 0.15 6 39 .. 3 36 .. 1 45 [. 0.74 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 3e-05 DUF4519 6 ggktKetrKqKkeRkkenkeiqdkvktvvlPvla 39 +g + ++++ + R en+++ ++v+tvv ++ FUN_001722-T1 3 KGPVERSNRERQKREYENRKVLKQVVTVVAVFIS 36 5778889999999999999999999999843333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1172 (0.0458798); expected 510.9 (0.02) Passed bias filter: 803 (0.0314347); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1275.58 // Query: FUN_001723-T1 [L=369] Description: FUN_001723 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-10 40.1 0.1 1.3e-09 39.4 0.1 1.3 1 CAP Cysteine-rich secretory protein family Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.4 0.1 5.2e-14 1.3e-09 1 106 [. 234 347 .. 234 355 .. 0.89 Alignments for each domain: == domain 1 score: 39.4 bits; conditional E-value: 5.2e-14 CAP 1 ldlhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagr.eniaageesaedavkgWydepgtynygaa.......h 88 l++hN R+ +++p L+ d++L + Aq a ++a++g+ +h+s + + + a ++ ++ +a + Wyde +++n++ + FUN_001723-T1 234 LSAHNFKRQIHKVPLLAEDNQLDTEAQGFAMKLAKQGNITHSSLQDRLGQGENIAIRCaLKAPVAKLTGIRATNLWYDEGKNFNWNLKslspttqR 329 689********************************9966666666666666666666567889999****************************** PP CAP 89 rtnllwpkstkvGcavak 106 +t+++w+++tk G++ ak FUN_001723-T1 330 FTQMVWKNTTKAGFGRAK 347 ***************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (369 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 505 (0.019769); expected 510.9 (0.02) Passed bias filter: 430 (0.016833); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3614.57 // Query: FUN_001724-T1 [L=220] Description: FUN_001724 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-24 88.6 1.2 1.7e-24 87.9 1.2 1.3 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.02 15.9 0.1 0.042 14.9 0.1 1.5 1 DUF5395 Family of unknown function (DUF5395) Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.9 1.2 1.3e-28 1.7e-24 8 227 .. 3 204 .. 1 209 [. 0.69 Alignments for each domain: == domain 1 score: 87.9 bits; conditional E-value: 1.3e-28 Neur_chan_memb 8 iviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsewvrklfle 102 +++ svl F p+++ ge+vtL I L+++v+++ +++ +P tS+++pli+k Ll m+ +sl+ + ln+ ++++m++wvr +fl+ FUN_001724-T1 3 VTSFSVLTFAFPPEC-GERVTLVIESFLAMSVVIFNVADDIPVTSISTPLIVKILLAAMIQIGFSLIANCVSLNMY----RNTEMPQWVRVFFLH 92 6788***********.********************************************9999988777777776....4689*********** PP Neur_chan_memb 103 klprlllmkrpkeeeeeeassagssskaeelilkksrselkaekqsersglerettestessegkelkqs..eelspelekaveev.nfiakhlr 194 l r+l+m + + +++ +s ++ + +e+ ++++l+++++ + + ++ + e+ +p + k++e++ ++++++lr FUN_001724-T1 93 YLARMLCMDTGHP-KADVMSVRRVNA-------------RVDETELNNHKLAGAKPFQPVNWIPGKVPEIetEHTNP-IIKMTEGItEVVRGSLR 172 ********87532.222222222222.............22222223333333333333332222222212133334.33333333034457777 PP Neur_chan_memb 195 eedkkeevkedwklvakviDrlsliifpivfvl 227 eed++++ ke w ++++ Dr+++i+ i+f++ FUN_001724-T1 173 EEDNERD-KEFWIFASQIADRIFMIVLSIFFFF 204 7766655.667*************999988865 PP >> DUF5395 Family of unknown function (DUF5395) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.1 3.3e-06 0.042 51 80 .. 73 101 .. 64 102 .. 0.80 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 3.3e-06 DUF5395 51 evfmkfDyetiPeWirqyaphYfnRvvele 80 +++m + ++ +P+W+r + hY+ R++ ++ FUN_001724-T1 73 SLNM-YRNTEMPQWVRVFFLHYLARMLCMD 101 5555.456779**************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (220 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 740 (0.0289685); expected 510.9 (0.02) Passed bias filter: 459 (0.0179683); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2159.88 // Query: FUN_001725-T1 [L=356] Description: FUN_001725 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-31 110.0 0.4 3.9e-31 109.6 0.4 1.2 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr 4.2e-29 102.0 0.1 6e-29 101.5 0.1 1.2 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.6 0.4 3.1e-35 3.9e-31 1 233 [] 131 345 .. 131 345 .. 0.75 Alignments for each domain: == domain 1 score: 109.6 bits; conditional E-value: 3.1e-35 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 +iiPc+ i +L++l F Lp++ ge+vtL I L+l+ ++l++++ +P tS + pli k+L++ m+ +l+ + ln+h ++ +m++w FUN_001725-T1 131 IIIPCLVIASLAILTFVLPPEI-GERVTLVIESFLALSFVVLMVSDNVPVTSDSSPLITKFLIISMIEIGGALIANCVSLNLH----RKYEMPQW 220 79********************.**************************************************9999999999....4789**** PP Neur_chan_memb 96 vrklfleklprlllmkrpkeeeeeeassagssskaeelilkksrselkaekqsersglerettestessegkelkqs...eelspelekaveevn 187 vr +fl+ l r l+++ + e + + ++ +++ + l a k se + l++++ +s + + +++++ + l++e+++ FUN_001725-T1 221 VRVVFLHFLARCLCINSGQPRE---------GINVKKGKDREADPFLDAIKLSEAKPLGSPSGPSPSHLKIPNCTHQdnsSILAEEVSQL----- 301 ***************9864433.........22223333333333344444444555555555555554444454431103344433333..... PP Neur_chan_memb 188 fiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 a+ ++++e + w +v++v+Drl+l+if i+fv+ ++vif FUN_001725-T1 302 --ANLELTHEQNQENRFFWIFVSRVVDRLFLVIFSITFVVSSFVIF 345 ..33333333333444469************************998 PP >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 101.5 0.1 4.7e-33 6e-29 103 216 .] 19 124 .. 13 124 .. 0.96 Alignments for each domain: == domain 1 score: 101.5 bits; conditional E-value: 4.7e-33 Neur_chan_LBD 103 ntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakreekktgsy 198 + v+++sdG+++w+ p i++s C+id++yFPfD+q C+lkf+Swtyn+ ev++ + +++dl+++++++e el++++a+r+ +++++ FUN_001725-T1 19 KNRVILTSDGECTWYAPTILRSGCNIDITYFPFDDQLCELKFGSWTYNGLEVNVVQMS-------DRADLKQYMTSSEFELISAKAQRNVITYSCC 107 567999************************************************9999.......789**************************** PP Neur_chan_LBD 199 selsysdvtftltlrRkp 216 e+ y+dvtftl+lrRkp FUN_001725-T1 108 PEP-YPDVTFTLHLRRKP 124 **9.8***********97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (356 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 725 (0.0283813); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3388.41 // Query: FUN_001726-T1 [L=180] Description: FUN_001726 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-09 37.4 0.1 4.3e-09 36.6 0.1 1.4 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bind Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.6 0.1 1.7e-13 4.3e-09 3 55 .. 121 173 .. 119 174 .. 0.96 Alignments for each domain: == domain 1 score: 36.6 bits; conditional E-value: 1.7e-13 Neur_chan_LBD 3 rlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkq 55 rl++dl+++Yd++vrP+++++ pv+V++++ +q++++ ek+q+l n+w+++ FUN_001726-T1 121 RLVNDLFNDYDRNVRPAKEKHLPVEVKFGIAYTQVVDLIEKDQVLVSNIWVRM 173 89************************************************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (180 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 722 (0.0282638); expected 510.9 (0.02) Passed bias filter: 461 (0.0180466); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1819.52 // Query: FUN_001727-T1 [L=491] Description: FUN_001727 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-59 201.6 1.3 1.8e-59 201.3 1.3 1.1 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 2.1e-44 153.0 0.1 3e-44 152.5 0.1 1.2 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.22 11.9 0.1 0.38 11.2 0.1 1.3 1 TGFBR3_N TGFBR3-like, N-terminal domain Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 201.3 1.3 2.1e-63 1.8e-59 3 216 .] 29 237 .. 27 237 .. 0.95 Alignments for each domain: == domain 1 score: 201.3 bits; conditional E-value: 2.1e-63 Neur_chan_LBD 3 rlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlynkadg... 95 +l++ l+++Y+k+vrPv+n+++ ++V++++ +q++++deknq+l nvw++q+W+ + L+wn+++yg+i+s++++ +++W+Pdivlyn+a++ FUN_001727-T1 29 ELVKYLFDNYSKEVRPVKNKNTSIEVHFGIAYTQLVELDEKNQVLVSNVWIRQRWNNHLLRWNESKYGNITSINVDPKEVWVPDIVLYNNANTgii 124 799**************************************************************************************7765222 PP Neur_chan_LBD 96 ehevtekntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakre 191 + ++++ +t v+++s+G+ +w p i++s C id++yFPfD+q+C+l f+Swty++ v+l + + +dl++++++ge e+v+++++r+ FUN_001727-T1 125 SGNMDQFKTRVILKSNGDNTWFAPTILRSRCAIDITYFPFDDQKCDLHFGSWTYDGLRVNLVNVS-------KGVDLKSYMPSGEFEMVDAPVERK 213 346777899****************************************************9999.......79********************** PP Neur_chan_LBD 192 ekktgsyselsysdvtftltlrRkp 216 ++++ e y+++ ftl++rRk+ FUN_001727-T1 214 VIRYSCCPEA-YPNLFFTLHIRRKV 237 ******9998.8***********95 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.5 0.1 3.5e-48 3e-44 1 233 [] 244 482 .. 244 482 .. 0.81 Alignments for each domain: == domain 1 score: 152.5 bits; conditional E-value: 3.5e-48 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhh.rspsthkmse 94 li+Pc li+ + l F Lp++ ge+vtL It+lL++Tvf+l+i+e P tS v+pligk+++ mv l+l+ t +Vln+ pst +++ FUN_001727-T1 244 LIVPCFLITAFALLTFVLPPNT-GERVTLVITTLLAMTVFMLMIAENTPTTSDVTPLIGKFFVASMVEIGLALIATCFVLNLYEgTGPST-DVPQ 336 69********************.*************************************************************777775.9*** PP Neur_chan_memb 95 wvrklfleklprlllmkrpkeeeeeea...ssagssskaeelilkksrselkaekqsersglerettestessegkelkqs.......eelspel 179 wvr l+++ l +l++ rpk+++++ +s+ s + + ++ + e+ + ++ + ++r ++ +s++ + ++ + FUN_001727-T1 337 WVRVLLVDFLAPILRVARPKSKPQRRFtpyNSNIHSYSPIMAERNGNTPEVDGTPKDLLVIAPRVGDKVLTSRDFIN---TvndnnlrHRGPSTQ 428 *******************8888776656533333333334444444444444444444444444444333333222...122356756666678 PP Neur_chan_memb 180 ekaveevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 +k++e++ ++a++ r+++k++e+ke+w vakviDr++l++f++++++ t++if FUN_001727-T1 429 DKILEGITVLAERARDQEKQDEIKEEWESVAKVIDRFFLLLFMATVAISTALIF 482 999***********************************************9998 PP >> TGFBR3_N TGFBR3-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 4.5e-05 0.38 76 118 .. 59 101 .. 37 109 .. 0.66 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 4.5e-05 TGFBR3_N 76 avssnlvvfseslevnvtelplpt.skeqLlkWAlqkyggvtSf 118 a+++ v e+ +v v+++ + + +++Ll+W + kyg++tS+ FUN_001727-T1 59 AYTQL-VELDEKNQVLVSNVWIRQrWNNHLLRWNESKYGNITSI 101 44443.3344445555555555554699******88*******7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (491 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1143 (0.0447446); expected 510.9 (0.02) Passed bias filter: 773 (0.0302603); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.41s 00:00:00.75 Elapsed: 00:00:00.43 # Mc/sec: 4644.80 // Query: FUN_001727-T2 [L=496] Description: FUN_001727 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-59 201.6 1.3 1.9e-59 201.2 1.3 1.1 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 7.3e-45 154.5 0.2 3.1e-44 152.5 0.1 1.9 2 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.23 11.9 0.1 0.39 11.2 0.1 1.3 1 TGFBR3_N TGFBR3-like, N-terminal domain Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 201.2 1.3 2.2e-63 1.9e-59 3 216 .] 34 242 .. 32 242 .. 0.95 Alignments for each domain: == domain 1 score: 201.2 bits; conditional E-value: 2.2e-63 Neur_chan_LBD 3 rlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlynkadg... 95 +l++ l+++Y+k+vrPv+n+++ ++V++++ +q++++deknq+l nvw++q+W+ + L+wn+++yg+i+s++++ +++W+Pdivlyn+a++ FUN_001727-T2 34 ELVKYLFDNYSKEVRPVKNKNTSIEVHFGIAYTQLVELDEKNQVLVSNVWIRQRWNNHLLRWNESKYGNITSINVDPKEVWVPDIVLYNNANTgii 129 799**************************************************************************************7765222 PP Neur_chan_LBD 96 ehevtekntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakre 191 + ++++ +t v+++s+G+ +w p i++s C id++yFPfD+q+C+l f+Swty++ v+l + + +dl++++++ge e+v+++++r+ FUN_001727-T2 130 SGNMDQFKTRVILKSNGDNTWFAPTILRSRCAIDITYFPFDDQKCDLHFGSWTYDGLRVNLVNVS-------KGVDLKSYMPSGEFEMVDAPVERK 218 346777899****************************************************9999.......79********************** PP Neur_chan_LBD 192 ekktgsyselsysdvtftltlrRkp 216 ++++ e y+++ ftl++rRk+ FUN_001727-T2 219 VIRYSCCPEA-YPNLFFTLHIRRKV 242 ******9998.8***********95 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.2 1.7e+03 65 84 .. 7 26 .. 5 58 .. 0.80 2 ! 152.5 0.1 3.6e-48 3.1e-44 1 233 [] 249 487 .. 249 487 .. 0.81 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.2 Neur_chan_memb 65 cmvfvflslvetviVlnvhh 84 ++++v l+++++ +++ FUN_001727-T2 7 VFLLVYLAIINFTTINEALI 26 799**********9998665 PP == domain 2 score: 152.5 bits; conditional E-value: 3.6e-48 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhh.rspsthkmse 94 li+Pc li+ + l F Lp++ ge+vtL It+lL++Tvf+l+i+e P tS v+pligk+++ mv l+l+ t +Vln+ pst +++ FUN_001727-T2 249 LIVPCFLITAFALLTFVLPPNT-GERVTLVITTLLAMTVFMLMIAENTPTTSDVTPLIGKFFVASMVEIGLALIATCFVLNLYEgTGPST-DVPQ 341 69********************.*************************************************************777775.9*** PP Neur_chan_memb 95 wvrklfleklprlllmkrpkeeeeeea...ssagssskaeelilkksrselkaekqsersglerettestessegkelkqs.......eelspel 179 wvr l+++ l +l++ rpk+++++ +s+ s + + ++ + e+ + ++ + ++r ++ +s++ + ++ + FUN_001727-T2 342 WVRVLLVDFLAPILRVARPKSKPQRRFtpyNSNIHSYSPIMAERNGNTPEVDGTPKDLLVIAPRVGDKVLTSRDFIN---TvndnnlrHRGPSTQ 433 *******************8888776656533333333334444444444444444444444444444333333222...122356756666678 PP Neur_chan_memb 180 ekaveevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 +k++e++ ++a++ r+++k++e+ke+w vakviDr++l++f++++++ t++if FUN_001727-T2 434 DKILEGITVLAERARDQEKQDEIKEEWESVAKVIDRFFLLLFMATVAISTALIF 487 999***********************************************9998 PP >> TGFBR3_N TGFBR3-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 4.5e-05 0.39 76 118 .. 64 106 .. 42 114 .. 0.66 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 4.5e-05 TGFBR3_N 76 avssnlvvfseslevnvtelplpt.skeqLlkWAlqkyggvtSf 118 a+++ v e+ +v v+++ + + +++Ll+W + kyg++tS+ FUN_001727-T2 64 AYTQL-VELDEKNQVLVSNVWIRQrWNNHLLRWNESKYGNITSI 106 44443.3344445555555555554699******88*******7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (496 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1194 (0.046741); expected 510.9 (0.02) Passed bias filter: 784 (0.0306909); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 4703.04 // Query: FUN_001727-T3 [L=546] Description: FUN_001727 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-59 201.4 1.3 2.3e-59 200.9 1.3 1.2 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bin 2.3e-44 152.9 0.1 3.9e-44 152.1 0.1 1.4 1 Neur_chan_memb Neurotransmitter-gated ion-channel transmembr ------ inclusion threshold ------ 0.19 12.2 0.0 0.34 11.3 0.0 1.4 1 TGFBR3_N TGFBR3-like, N-terminal domain 0.25 12.1 0.1 0.84 10.4 0.0 1.9 2 E_motif E motif Domain annotation for each model (and alignments): >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 200.9 1.3 3.6e-63 2.3e-59 3 216 .] 84 292 .. 82 292 .. 0.95 Alignments for each domain: == domain 1 score: 200.9 bits; conditional E-value: 3.6e-63 Neur_chan_LBD 3 rlledllegYdklvrPveneskpvtVslelslsqiisvdeknqelttnvwlkqkWtDerLkwnpedyggieslrlpsekiWlPdivlynkadg... 95 +l++ l+++Y+k+vrPv+n+++ ++V++++ +q++++deknq+l nvw++q+W+ + L+wn+++yg+i+s++++ +++W+Pdivlyn+a++ FUN_001727-T3 84 ELVKYLFDNYSKEVRPVKNKNTSIEVHFGIAYTQLVELDEKNQVLVSNVWIRQRWNNHLLRWNESKYGNITSINVDPKEVWVPDIVLYNNANTgii 179 799**************************************************************************************7765222 PP Neur_chan_LBD 96 ehevtekntnvrvssdGtvlwsppaivkssCsidvkyFPfDeqnCslkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakre 191 + ++++ +t v+++s+G+ +w p i++s C id++yFPfD+q+C+l f+Swty++ v+l + + +dl++++++ge e+v+++++r+ FUN_001727-T3 180 SGNMDQFKTRVILKSNGDNTWFAPTILRSRCAIDITYFPFDDQKCDLHFGSWTYDGLRVNLVNVS-------KGVDLKSYMPSGEFEMVDAPVERK 268 346777899****************************************************9999.......79********************** PP Neur_chan_LBD 192 ekktgsyselsysdvtftltlrRkp 216 ++++ e y+++ ftl++rRk+ FUN_001727-T3 269 VIRYSCCPEA-YPNLFFTLHIRRKV 292 ******9998.8***********95 PP >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.1 0.1 6.1e-48 3.9e-44 1 233 [] 299 537 .. 299 537 .. 0.81 Alignments for each domain: == domain 1 score: 152.1 bits; conditional E-value: 6.1e-48 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhh.rspsthkmse 94 li+Pc li+ + l F Lp++ ge+vtL It+lL++Tvf+l+i+e P tS v+pligk+++ mv l+l+ t +Vln+ pst +++ FUN_001727-T3 299 LIVPCFLITAFALLTFVLPPNT-GERVTLVITTLLAMTVFMLMIAENTPTTSDVTPLIGKFFVASMVEIGLALIATCFVLNLYEgTGPST-DVPQ 391 69********************.*************************************************************777775.9*** PP Neur_chan_memb 95 wvrklfleklprlllmkrpkeeeeeea...ssagssskaeelilkksrselkaekqsersglerettestessegkelkqs.......eelspel 179 wvr l+++ l +l++ rpk+++++ +s+ s + + ++ + e+ + ++ + ++r ++ +s++ + ++ + FUN_001727-T3 392 WVRVLLVDFLAPILRVARPKSKPQRRFtpyNSNIHSYSPIMAERNGNTPEVDGTPKDLLVIAPRVGDKVLTSRDFIN---TvndnnlrHRGPSTQ 483 *******************8888776656533333333334444444444444444444444444444333333222...122356756666678 PP Neur_chan_memb 180 ekaveevnfiakhlreedkkeevkedwklvakviDrlsliifpivfvlgtlvif 233 +k++e++ ++a++ r+++k++e+ke+w vakviDr++l++f++++++ t++if FUN_001727-T3 484 DKILEGITVLAERARDQEKQDEIKEEWESVAKVIDRFFLLLFMATVAISTALIF 537 999***********************************************9998 PP >> TGFBR3_N TGFBR3-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 5.3e-05 0.34 76 118 .. 114 156 .. 60 164 .. 0.73 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 5.3e-05 TGFBR3_N 76 avssnlvvfseslevnvtelplpt.skeqLlkWAlqkyggvtSf 118 a+++ v e+ +v v+++ + + +++Ll+W + kyg++tS+ FUN_001727-T3 114 AYTQL-VELDEKNQVLVSNVWIRQrWNNHLLRWNESKYGNITSI 156 44443.3344455566666666554699******88*******7 PP >> E_motif E motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 1.9 1.2e+04 35 49 .. 77 91 .. 64 99 .. 0.60 2 ? 10.4 0.0 0.00013 0.84 9 38 .. 113 139 .. 108 151 .. 0.84 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 1.9 E_motif 35 agrwkdVerirkkmK 49 + + + e+++++ FUN_001727-T3 77 NRDDDELELVKYLFD 91 466777888887765 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00013 E_motif 9 kAankLlElekkndgnyvLlsNiyaeagrw 38 +A +L+El++kn+ vL+sN++ ++ FUN_001727-T3 113 IAYTQLVELDEKNQ---VLVSNVWIRQRWN 139 6999******9986...9******987643 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (546 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 952 (0.0372676); expected 510.9 (0.02) Passed bias filter: 617 (0.0241535); expected 510.9 (0.02) Passed Vit filter: 62 (0.00242709); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.43 # Mc/sec: 5170.09 // Query: FUN_001728-T1 [L=392] Description: FUN_001728 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.055 14.1 2.2 0.1 13.2 0.2 2.6 2 zf-CCHC Zinc knuckle 3.2 8.5 13.5 0.17 12.6 5.5 2.8 3 zf-UBP Zn-finger in ubiquitin-hydrolases and other protein 3.7 7.7 8.9 1.4 9.1 4.4 2.0 2 RR_TM4-6 Ryanodine Receptor TM 4-6 Domain annotation for each model (and alignments): >> zf-CCHC Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.2 1.2e-05 0.1 2 17 .. 240 255 .. 240 256 .. 0.95 2 ? -1.8 0.1 0.68 5.8e+03 6 12 .. 324 330 .. 324 331 .. 0.88 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1.2e-05 zf-CCHC 2 kCynCGepGHiardCp 17 kC++C ++GH+ dC+ FUN_001728-T1 240 KCWKCSRVGHLPDDCT 255 7**************8 PP == domain 2 score: -1.8 bits; conditional E-value: 0.68 zf-CCHC 6 CGepGHi 12 C + GH+ FUN_001728-T1 324 CDGRGHL 330 9999**6 PP >> zf-UBP Zn-finger in ubiquitin-hydrolases and other protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.1 0.24 2e+03 9 20 .. 237 248 .. 232 253 .. 0.81 2 ? 12.6 5.5 2e-05 0.17 1 45 [. 304 347 .. 304 364 .. 0.81 3 ? -2.7 1.0 1.2 1e+04 3 16 .. 358 373 .. 354 376 .. 0.72 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.24 zf-UBP 9 nlWlCltCgkvg 20 + + C +C +vg FUN_001728-T1 237 STYKCWKCSRVG 248 678899999997 PP == domain 2 score: 12.6 bits; conditional E-value: 2e-05 zf-UBP 1 CseCgstenlWlCltCgkvgCgryqnshaleHye.etgHplavkle 45 Cs+Cg ++nl Cl+Cg +C ++h ++H +H+ +++ FUN_001728-T1 304 CSDCGGKSNLAYCLECGLTLCDG--RGHLIDHLLeYPNHCKLYSFK 347 *********************84..799999997366787666655 PP == domain 3 score: -2.7 bits; conditional E-value: 1.2 zf-UBP 3 eCgst..enlWlCltC 16 +C+ +l +C +C FUN_001728-T1 358 TCEVVdaRELLMCSSC 373 5665556889999999 PP >> RR_TM4-6 Ryanodine Receptor TM 4-6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.065 5.5e+02 98 121 .. 75 98 .. 30 116 .. 0.53 2 ? 9.1 4.4 0.00016 1.4 15 97 .. 139 216 .. 130 240 .. 0.70 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.065 RR_TM4-6 98 ekeeeeepkaeeekadsedgekee 121 +++e++ k ++k+ + +++k+e FUN_001728-T1 75 GMKREKQIKKRRRKRRKPNTDKTE 98 112222222222222222222222 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00016 RR_TM4-6 15 seaekkeeeeasgkedlaeakgeeeeedllsdifgldlkkeggqyklvkkdaeagLgdlsettaeetppelkkklqeeeeaed 97 ++ k++++e+s++++ + +++++ed+ +d fgl k+e++ +l + +++++ g+ s+++ + + ++lk+ + +++++++ FUN_001728-T1 139 GDDSKMNKSENSISSN---SCSGSDDEDVDVDFFGLSSKQENS--RLEHSGTKKTSGESSNKEQSMKHNTLKRSQPQQSIEAE 216 3444555555555533...56799*******************..99999999999999888887776555544444333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (392 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1828 (0.07156); expected 510.9 (0.02) Passed bias filter: 616 (0.0241143); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.42s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3899.41 // Query: FUN_001728-T2 [L=302] Description: FUN_001728 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.015 16.3 1.9 0.24 12.4 0.1 2.6 3 DUF702 Domain of unknown function (DUF702) 0.032 14.8 0.2 0.074 13.7 0.2 1.6 1 zf-CCHC Zinc knuckle 1 9.6 8.2 0.55 10.4 3.8 2.0 2 RR_TM4-6 Ryanodine Receptor TM 4-6 Domain annotation for each model (and alignments): >> DUF702 Domain of unknown function (DUF702) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.8 6.8e+03 114 130 .. 2 18 .. 1 23 [. 0.86 2 ? 2.6 0.1 0.029 2.5e+02 70 90 .. 76 101 .. 60 154 .. 0.51 3 ? 12.4 0.1 2.8e-05 0.24 58 125 .. 185 252 .. 166 270 .. 0.47 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.8 DUF702 114 cvrvsavddgeeevaYq 130 cv++ + +++ + + Y FUN_001728-T2 2 CVKMNSFNNKRQAYMYA 18 99*****9999999986 PP == domain 2 score: 2.6 bits; conditional E-value: 0.029 DUF702 70 sasssekskrpree.....saaasas 90 ++++++ +kr r++ ++++ + FUN_001728-T2 76 MKREKQIKKRRRKRrkpntDKTEDVA 101 22222223333322111111111111 PP == domain 3 score: 12.4 bits; conditional E-value: 2.8e-05 DUF702 58 aqaaeaeaeaassasssekskrpreesaaasassts..attskseslpeevsseAvFrcvrvsavddgee 125 +++++ e+++++++ ++++ kr + + ++ ++ + s + ++ e+vs+ +++c + s v + + FUN_001728-T2 185 TKKTSGESSNKEQSMKHNTLKRSQPQ--QSIEAERQpvVWDSMKLKFKEQVSTLSTYKCWKCSRVGHLPD 252 11111111112222222223333322..111111112222223349**********99999998865433 PP >> zf-CCHC Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.2 8.7e-06 0.074 2 17 .. 240 255 .. 240 256 .. 0.95 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 8.7e-06 zf-CCHC 2 kCynCGepGHiardCp 17 kC++C ++GH+ dC+ FUN_001728-T2 240 KCWKCSRVGHLPDDCT 255 7**************8 PP >> RR_TM4-6 Ryanodine Receptor TM 4-6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.1 0.042 3.6e+02 97 121 .. 74 98 .. 27 116 .. 0.54 2 ? 10.4 3.8 6.5e-05 0.55 15 97 .. 139 216 .. 130 241 .. 0.70 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.042 RR_TM4-6 97 dekeeeeepkaeeekadsedgekee 121 + +++e++ k ++k+ + +++k+e FUN_001728-T2 74 EGMKREKQIKKRRRKRRKPNTDKTE 98 1122222222222222222222222 PP == domain 2 score: 10.4 bits; conditional E-value: 6.5e-05 RR_TM4-6 15 seaekkeeeeasgkedlaeakgeeeeedllsdifgldlkkeggqyklvkkdaeagLgdlsettaeetppelkkklqeeeeaed 97 ++ k++++e+s++++ + +++++ed+ +d fgl k+e++ +l + +++++ g+ s+++ + + ++lk+ + +++++++ FUN_001728-T2 139 GDDSKMNKSENSISSN---SCSGSDDEDVDVDFFGLSSKQENS--RLEHSGTKKTSGESSNKEQSMKHNTLKRSQPQQSIEAE 216 3444555555555533...56799*******************..99999999999999888887776555544443333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (302 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1672 (0.0654531); expected 510.9 (0.02) Passed bias filter: 591 (0.0231356); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 3081.34 // Query: FUN_001729-T1 [L=66] Description: FUN_001729 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.11 12.9 0.1 0.21 12.0 0.1 1.5 1 DUF7685 Domain of unknown function (DUF7685) Domain annotation for each model (and alignments): >> DUF7685 Domain of unknown function (DUF7685) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 8.2e-06 0.21 25 34 .. 13 22 .. 5 23 .. 0.83 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 8.2e-06 DUF7685 25 rlLCldCyNe 34 lLC++CyN+ FUN_001729-T1 13 NLLCRKCYNK 22 58*******8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (66 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 751 (0.0293991); expected 510.9 (0.02) Passed bias filter: 398 (0.0155803); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 667.30 // Query: FUN_001730-T1 [L=129] Description: FUN_001730 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-31 108.5 0.1 2.8e-31 108.2 0.1 1.0 1 GSKIP_dom GSKIP domain ------ inclusion threshold ------ 0.015 14.5 0.0 0.017 14.3 0.0 1.1 1 SHMT Serine hydroxymethyltransferase Domain annotation for each model (and alignments): >> GSKIP_dom GSKIP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 108.2 0.1 2.2e-35 2.8e-31 2 105 .] 15 114 .. 14 114 .. 0.98 Alignments for each domain: == domain 1 score: 108.2 bits; conditional E-value: 2.2e-35 GSKIP_dom 2 keEaeaavndvafaVkeisvseklpsteevvylnvetkEgnelcielsakGfrivgskndtvkeksekedetkyyetlyaLLdkiSpkyrekFgek 97 + Eaea+++d+ f Vk+i +s+klp ++e vylnv tkE+++lc+els+ Gf +vg+++d+ +++ +kyyet++aLLd+iSp y ++Fge+ FUN_001730-T1 15 RVEAEAVMKDIGFTVKSINISSKLPASRECVYLNVLTKESKCLCVELSVLGFLVVGERFDEN----KATSASKYYETMNALLDSISPGYCHSFGEA 106 78************************************************************....9999************************** PP GSKIP_dom 98 llekLeel 105 l++kL+ l FUN_001730-T1 107 LVQKLSSL 114 *****976 PP >> SHMT Serine hydroxymethyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 1.3e-06 0.017 100 150 .. 43 93 .. 14 99 .. 0.87 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.3e-06 SHMT 100 lavytallepgdrllgldlpdGGhlthGykvdskkisassklfesvpykvd 150 vy +l ++ + l ++l+ G l G + d++k + +sk++e+++ +d FUN_001730-T1 43 ECVYLNVLTKESKCLCVELSVLGFLVVGERFDENKATSASKYYETMNALLD 93 469******************************************986665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 808 (0.0316305); expected 510.9 (0.02) Passed bias filter: 716 (0.028029); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1284.36 // Query: FUN_001731-T1 [L=439] Description: FUN_001731 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-13 50.6 0.0 1.3e-06 28.5 0.0 2.3 2 Pyr_redox_2 Pyridine nucleotide-disulphide oxidoreductase ------ inclusion threshold ------ 0.09 12.3 0.0 12 5.3 0.0 2.1 2 Lycopene_cycl Lycopene cyclase protein 0.13 11.9 0.1 0.19 11.3 0.1 1.2 1 DUF4317 Domain of unknown function (DUF4317) Domain annotation for each model (and alignments): >> Pyr_redox_2 Pyridine nucleotide-disulphide oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 0.0 1.6e-10 1.3e-06 2 119 .. 31 142 .. 30 170 .. 0.82 2 ! 19.8 0.0 7.2e-08 0.00062 183 286 .. 225 334 .. 196 342 .. 0.75 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 1.6e-10 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Pyr_redox_2 2 dvvviGaGpAGlaaaltlaq.aglkvtliedegtclnggcvlskallaaaeaaeiaseevkklnngievllgkevvkidkgekkvkleekvegkge 96 + vv+G+G +G+a tl + + +++++i + ++ ++ +++ + + + ++ ++++ + ++++ +++ + +vv++++++ ++ +g+ FUN_001731-T1 31 QFVVVGGGSGGMAISSTLCRkYPHSTAII-EPSENHYYQPLWTLVGGGIEHLDQSVRPTSSLISSDCTWFKT-KVVEFNPEKNIIVT-----ADGN 119 78****************9978*******.777788999999888888888888777545667778998888.9****999866666.....6788 PP xxxxxxxxxxxxxxxxxxxxxxx RF Pyr_redox_2 97 eleydklviAtGarprllgipGv 119 e+ y+ l++A G + r ++ G+ FUN_001731-T1 120 EIGYEFLIVAVGLQLRYDKVAGL 142 ************98877777777 PP == domain 2 score: 19.8 bits; conditional E-value: 7.2e-08 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxx.xxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx.xxxxx.x RF Pyr_redox_2 183 keisealekalekeGvevrlgtsvkeiegdgd..kle.vllkdgee.....ieadlvvvaiGvrpntelleaaglel.derggivvde.ylrts.v 267 ++ ++ l+ ++k+++++ ++++ ei+ +++ vl+++++e +++d++ v + p + l +g ++ d +g++ vd+ ++r + FUN_001731-T1 225 QKYADSLRSIIKKRDIQLNFKRNLIEIKPETKeaI-FeVLDGSQTEkkletYQYDMIHVTPPMGPPDCL---LGSPIsDGNGFVDVDKiTMRHKkY 316 45677788999*********************752.246666666667778***************988...46666467888899985567767* PP xxxxxxxxxxxxxxxxxxx RF Pyr_redox_2 268 pgiyAiGDvakgrpelaqn 286 p+i+A+GD+a ++p+ ++ FUN_001731-T1 317 PNIFALGDCA-NSPNGKTA 334 **********.55543333 PP >> Lycopene_cycl Lycopene cyclase protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.0015 12 3 45 .. 33 72 .. 31 88 .. 0.77 2 ? 5.0 0.0 0.0017 15 97 157 .. 91 147 .. 81 151 .. 0.84 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0015 Lycopene_cycl 3 vviGaGpAglslAarlteakpglkvvlieaspsllfpnnyvWs 45 vv+G+G g+++ l k+ + +ie+s++ + + W FUN_001731-T1 33 VVVGGGSGGMAISSTL-CRKYPHSTAIIEPSENHYYQP--LWT 72 9***************.6677788999****9985433..455 PP == domain 2 score: 5.0 bits; conditional E-value: 0.0017 Lycopene_cycl 97 lvengvklleakvesveeeeageslvvleggrkirarlvvdarglaslkkarrlglQtayG 157 l+++ ++ + kv + ++e++ +v+++g++i + ++a g +l+ + glQ+a+G FUN_001731-T1 91 LISSDCTWFKTKVVEFNPEKN---IIVTADGNEIGYEFLIVAVG-LQLRYDKVAGLQQAFG 147 566677777888877777777...9*******************.7788888899999998 PP >> DUF4317 Domain of unknown function (DUF4317) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 2.2e-05 0.19 289 348 .. 201 260 .. 195 268 .. 0.90 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 2.2e-05 DUF4317 289 LeesGveeeklekvekafeevvgdektelkasniikskslkiktkdvsikvkpekldlvk 348 +++ Gv +++ +++a ++++g +k+ ++iik++ ++ + k i++kpe +++ FUN_001731-T1 201 FRDHGVRDKTKVMFNSALDKIFGVQKYADSLRSIIKKRDIQLNFKRNLIEIKPETKEAIF 260 5788**************************************************998885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (439 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 524 (0.0205128); expected 510.9 (0.02) Passed bias filter: 498 (0.019495); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4298.12 // Query: FUN_001732-T1 [L=102] Description: FUN_001732 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 357 (0.0139753); expected 510.9 (0.02) Passed bias filter: 278 (0.0108828); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1039.99 // Query: FUN_001733-T1 [L=372] Description: FUN_001733 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-40 138.8 29.3 2.9e-40 138.8 29.3 1.9 2 TRAM_LAG1_CLN8 TLC domain Domain annotation for each model (and alignments): >> TRAM_LAG1_CLN8 TLC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.5 0.056 1.4e+03 129 151 .. 44 67 .. 13 83 .. 0.71 2 ! 138.8 29.3 1.1e-44 2.9e-40 2 197 .. 87 292 .. 86 293 .. 0.93 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.056 TRAM_LAG1_CLN8 129 ksadvlf.vlflvsFflvRlvlgp 151 +++dvl+ + + v+F+++R +l + FUN_001733-T1 44 STKDVLLtLSLGVFFTILRYLLTV 67 467777778888888888877653 PP == domain 2 score: 138.8 bits; conditional E-value: 1.1e-44 TRAM_LAG1_CLN8 2 fdergvslvyylvstilglyvlssepw.....lkelwedy.pdrvlgatslllkfyyliqlgyfiwdllvllfyekkrkdfwemllHhvitllli 90 e++++++yy+++ + +y+l++ ++ k++w ++ + +++ + +++y++q+g++++++++++f++++r df++m+lHh++t++l+ FUN_001733-T1 87 APESAFKFLYYSMAYGYTCYILFNGKYsffqeSKHCWIGWyKGMPVAQ---DIYVVYVVQAGFYLHSIYATVFMDQWRRDFILMILHHILTFALL 178 5799*************************************9999999...9******************************************* PP TRAM_LAG1_CLN8 91 vlsylrnflrvgllvlllhelsdpflnlakilkylkkk.........ksadvlfvlflvsFflvRlvlgpflillsileeakedvetgeplllyv 176 ++s+ +++r+gllvl+lh+++d+fl+lak++ k +a + f +f++s+f++Rl+l+p+++l+s+ ++dv + + y+ FUN_001733-T1 179 TFSFAIRYHRIGLLVLFLHDVCDVFLELAKLFVAFKTRggkycivsdVLAGINFCIFTLSWFYCRLYLYPIKVLHSCGSSEARDVLP--TAPFYF 271 ***********************************6666988865443455555*************************99999986..58**** PP TRAM_LAG1_CLN8 177 iflilllvLqllniyWfykil 197 +f+++l++L+++n++Wf il FUN_001733-T1 272 FFNTMLWCLLVMNVWWFQYIL 292 *****************9886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (372 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 882 (0.0345273); expected 510.9 (0.02) Passed bias filter: 410 (0.0160501); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 3678.70 // Query: FUN_001734-T1 [L=247] Description: FUN_001734 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-50 172.2 25.9 1.6e-50 171.8 25.9 1.1 1 Folate_rec Folate receptor family Domain annotation for each model (and alignments): >> Folate_rec Folate receptor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 171.8 25.9 6.2e-55 1.6e-50 1 171 [. 35 200 .. 35 202 .. 0.96 Alignments for each domain: == domain 1 score: 171.8 bits; conditional E-value: 6.2e-55 Folate_rec 1 vClegkhhkekpspeeklleeCapykensCCtaetseelakdesi.lsnfswerCgelskeCekfleqlecfyecspnlgpwikperkerilkvpl 95 +C++g+ hk kp+p++ + eC +k++sCCtae+++el++++ l+nfsw++C +ls++Ce+f++++ecf++c+pnl +w + + ++ +vp+ FUN_001734-T1 35 QCIDGPLHKDKPTPQDSGYVECLSWKDKSCCTAEFTQELQRNKVEvLYNFSWNHCNNLSQACEQFIKDEECFWQCEPNLIKWHTK--EGAVNRVPI 128 6****************************************99999************************************555..89******* PP Folate_rec 96 CkefCdewfeaCkedltcksnwlkgwnweseknkceakakCrtfkqvfangtdlcesiwgesfkvskksksskrCl 171 C+ +Cd+wfeaCk+d+tc+++wl+g+n +s+ ++c+++++Crtf++v+++g+ lc+++wg+sf+++ +s++C+ FUN_001734-T1 129 CSKYCDDWFEACKDDMTCAQDWLNGFNFTSNVYSCPTSSRCRTFSEVYKDGKGLCNTMWGKSFHYE----TSQNCM 200 ******************************************************************....566676 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (247 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1218 (0.0476806); expected 510.9 (0.02) Passed bias filter: 655 (0.025641); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2479.67 // Query: FUN_001735-T1 [L=146] Description: FUN_001735 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.4e-18 65.6 1.0 4.9e-08 33.7 0.0 2.1 2 EF-hand_7 EF-hand domain pair 6.8e-15 53.8 1.5 2.4e-06 27.3 0.2 4.2 6 EF-hand_6 EF-hand domain 1.5e-12 46.6 2.0 8e-06 25.5 0.5 4.5 6 EF-hand_1 EF hand domain 5.6e-06 27.1 1.8 0.0011 19.7 0.6 2.0 2 AIF-1 Allograft inflammatory factor 1 4.4e-05 23.6 2.4 0.8 10.0 0.0 3.5 3 EF-hand_8 EF-hand domain pair 7.1e-05 23.3 0.0 0.00024 21.6 0.0 1.8 2 EF-hand_SWAP70_N Switch-associated protein 70-like, N-termin 0.00044 20.1 0.1 0.0045 16.9 0.3 2.5 2 EF-hand_5 EF hand 0.0036 18.2 0.0 4.5 8.3 0.0 2.4 2 EF-hand_9 EF-hand domain 0.0065 17.0 0.0 1.3 9.7 0.0 2.9 3 WHD_MCM4 MCM4, winged helix domain 0.0071 17.2 0.4 1.5 9.7 0.1 2.5 2 EF-hand_FSTL1 Follistatin-related protein 1, EF-hand doma ------ inclusion threshold ------ 0.014 16.7 0.0 0.039 15.3 0.0 1.7 2 EF-hand_11 EF-hand domain 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 Ogg-HhH 8-oxoguanine DNA glycosylase Domain annotation for each model (and alignments): >> EF-hand_7 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 0.5 2e-10 4.2e-07 3 66 .. 12 70 .. 10 71 .. 0.89 2 ! 33.7 0.0 2.3e-11 4.9e-08 1 66 [. 81 144 .. 81 145 .. 0.95 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 2e-10 EF-hand_7 3 klkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 + ke+F+l+D d dG ++++el l+ + ++ge++++ e+eel+ + + +++f EFl+++ FUN_001735-T1 12 EFKECFNLFDGDSDGMVTEKELG-LIMR-SLGENITHFEIEELMTK---AGKQKVRFPEFLKML 70 6799*******************.6666.********999999665...88888*******985 PP == domain 2 score: 33.7 bits; conditional E-value: 2.3e-11 EF-hand_7 1 eeklkeaFkllDsdgdGyldveelkkllrkleegeplsdeeveelfkefDldkdGrisfeEFlely 66 e+++ aF +lD++++G++++++l++l++ ++g++l ee++++++++ l ++ +i ++++++++ FUN_001735-T1 81 EKEILAAFTALDREKTGSVSRSQLQHLMT--GTGDKLGTEEFDHMLRDLGLEGSTSIQYTDLVRAI 144 578999***********************..******************************99886 PP >> EF-hand_6 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.2 1.1e-09 2.4e-06 1 30 [] 12 41 .. 12 41 .. 0.97 2 ? -2.8 0.0 5.4 1.1e+04 17 29 .. 44 56 .. 44 61 .. 0.73 3 ? -1.1 0.0 1.5 3.2e+03 13 27 .. 57 71 .. 52 75 .. 0.78 4 ! 19.8 0.0 2.8e-07 0.0006 1 29 [. 83 111 .. 83 116 .. 0.88 5 ? 2.8 0.0 0.085 1.8e+02 16 30 .] 114 128 .. 110 128 .. 0.88 6 ? -2.8 0.0 5.6 1.2e+04 13 26 .. 131 144 .. 130 145 .. 0.74 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 1.1e-09 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrslG 30 e++e+F+lfD d dG ++ +El ++rslG FUN_001735-T1 12 EFKECFNLFDGDSDGMVTEKELGLIMRSLG 41 69**************************98 PP == domain 2 score: -2.8 bits; conditional E-value: 5.4 EF-hand_6 17 isleElraalrsl 29 i+ E+ +++++ FUN_001735-T1 44 ITHFEIEELMTKA 56 6667888887765 PP == domain 3 score: -1.1 bits; conditional E-value: 1.5 EF-hand_6 13 gdGyisleElraalr 27 g+ ++ + E+ ++l FUN_001735-T1 57 GKQKVRFPEFLKMLA 71 556778889999986 PP == domain 4 score: 19.8 bits; conditional E-value: 2.8e-07 EF-hand_6 1 elreaFklfDkdgdGyisleElraalrsl 29 e+ aF +D++++G++s+++l+++++ FUN_001735-T1 83 EILAAFTALDREKTGSVSRSQLQHLMTGT 111 5778**********************944 PP == domain 5 score: 2.8 bits; conditional E-value: 0.085 EF-hand_6 16 yisleElraalrslG 30 ++ eE+ ++lr lG FUN_001735-T1 114 KLGTEEFDHMLRDLG 128 6789********998 PP == domain 6 score: -2.8 bits; conditional E-value: 5.6 EF-hand_6 13 gdGyisleElraal 26 g+ +i + +l +a+ FUN_001735-T1 131 GSTSIQYTDLVRAI 144 56678889998886 PP >> EF-hand_1 EF hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.5 3.8e-09 8e-06 1 29 [] 12 40 .. 12 40 .. 0.96 2 ? -2.0 0.0 2.4 5e+03 17 28 .. 44 55 .. 43 56 .. 0.68 3 ? 0.5 0.0 0.38 8.1e+02 16 28 .. 60 72 .. 57 73 .. 0.77 4 ! 13.1 0.0 3.6e-05 0.077 1 27 [. 83 109 .. 83 111 .. 0.92 5 ? 0.9 0.0 0.29 6.1e+02 17 28 .. 115 126 .. 114 127 .. 0.80 6 ? 2.6 0.0 0.08 1.7e+02 1 27 [. 119 145 .. 119 146 .] 0.89 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 3.8e-09 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellkkl 29 e+ke F++fD D dG ++ +E+ ++++l FUN_001735-T1 12 EFKECFNLFDGDSDGMVTEKELGLIMRSL 40 79************************986 PP == domain 2 score: -2.0 bits; conditional E-value: 2.4 EF-hand_1 17 IdfeEfkellkk 28 I+ E el++k FUN_001735-T1 44 ITHFEIEELMTK 55 666677777775 PP == domain 3 score: 0.5 bits; conditional E-value: 0.38 EF-hand_1 16 kIdfeEfkellkk 28 k+ f Ef+++l++ FUN_001735-T1 60 KVRFPEFLKMLAE 72 56689****9975 PP == domain 4 score: 13.1 bits; conditional E-value: 3.6e-05 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellk 27 e+ +F +D+ + G ++++++++l++ FUN_001735-T1 83 EILAAFTALDREKTGSVSRSQLQHLMT 109 67789*********************8 PP == domain 5 score: 0.9 bits; conditional E-value: 0.29 EF-hand_1 17 IdfeEfkellkk 28 + eEf ++l++ FUN_001735-T1 115 LGTEEFDHMLRD 126 6679*****987 PP == domain 6 score: 2.6 bits; conditional E-value: 0.08 EF-hand_1 1 elkeiFrefDkDgdGkIdfeEfkellk 27 e++ + r + g+ I + +++++++ FUN_001735-T1 119 EFDHMLRDLGLEGSTSIQYTDLVRAIT 145 789999999999**********99986 PP >> AIF-1 Allograft inflammatory factor 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.6 5.2e-07 0.0011 37 105 .. 7 72 .. 2 87 .. 0.86 2 ! 7.0 0.0 0.0043 9.2 47 102 .. 88 143 .. 78 145 .. 0.91 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 5.2e-07 AIF-1 37 eskleafkkkymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkmmlG 105 es+++ fk+ + fd + +G + l ++ lG + th+e+ l+++ ++ + + +flkm+ FUN_001735-T1 7 ESQIDEFKECFNLFDGDSDGMVTEKELGLIMRSLGENITHFEIEELMTKA---GKQKVRFPEFLKMLAE 72 68899*****************************************9865...4567899999999754 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0043 AIF-1 47 ymefdlndeGdidlmslkrmleklGvakthlelkklisevtggssetisyrdflkm 102 + +d++++G + l++++ G e+ +++++ + s +i y+d+++ FUN_001735-T1 88 FTALDREKTGSVSRSQLQHLMTGTGDKLGTEEFDHMLRDLGLEGSTSIQYTDLVRA 143 677899999*************999999999**********************985 PP >> EF-hand_8 EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.5 0.6 0.0097 21 26 46 .. 12 32 .. 5 34 .. 0.89 2 ! 10.0 0.0 0.00038 0.8 11 44 .. 68 101 .. 60 109 .. 0.80 3 ! 5.8 0.0 0.0074 16 2 34 .. 112 144 .. 111 144 .. 0.86 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0097 EF-hand_8 26 evdtlfrefDtDgdGkisfee 46 e+ + f+ fD D dG ++++e FUN_001735-T1 12 EFKECFNLFDGDSDGMVTEKE 32 667779************999 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00038 EF-hand_8 11 kril.alLglqdlsedevdtlfrefDtDgdGkisf 44 k+ + ++ +e+e+ + f+++D+++ G++s FUN_001735-T1 68 KMLAeQTGKMI-STEKEILAAFTALDREKTGSVSR 101 44444455555.899******************97 PP == domain 3 score: 5.8 bits; conditional E-value: 0.0074 EF-hand_8 2 kgvItresLkrilalLglqdlsedevdtlfref 34 ++++++e++ + l++Lgl + + ++++l+r++ FUN_001735-T1 112 GDKLGTEEFDHMLRDLGLEGSTSIQYTDLVRAI 144 68999******99******88888888888876 PP >> EF-hand_SWAP70_N Switch-associated protein 70-like, N-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1 2.1e+03 16 41 .. 17 42 .. 12 74 .. 0.66 2 ! 21.6 0.0 1.1e-07 0.00024 9 43 .. 81 115 .. 73 142 .. 0.83 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1 EF-hand_SWAP70_N 16 FtaLdveqsgkvsKsqLkVLshnlct 41 F+ d + +g+v L +l+ FUN_001735-T1 17 FNLFDGDSDGMVTEKELGLIMRSLGE 42 67777777777777666655555554 PP == domain 2 score: 21.6 bits; conditional E-value: 1.1e-07 EF-hand_SWAP70_N 9 lksiwhaFtaLdveqsgkvsKsqLkVLshnlctvl 43 +k i aFtaLd+e++g vs+sqL+ L + + l FUN_001735-T1 81 EKEILAAFTALDREKTGSVSRSQLQHLMTGTGDKL 115 799*********************98876655555 PP >> EF-hand_5 EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.3 2.1e-06 0.0045 1 23 [. 13 35 .. 13 37 .. 0.89 2 ? -0.5 0.0 0.68 1.5e+03 3 19 .. 87 102 .. 85 108 .. 0.68 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 2.1e-06 EF-hand_5 1 lkdtFraiDlNgDGkIskeELkr 23 +k++F+ +D + DG ++ +EL FUN_001735-T1 13 FKECFNLFDGDSDGMVTEKELGL 35 5889****************975 PP == domain 2 score: -0.5 bits; conditional E-value: 0.68 EF-hand_5 3 dtFraiDlNgDGkIske 19 + F a+D+ + G +s++ FUN_001735-T1 87 A-FTALDREKTGSVSRS 102 4.999998777777776 PP >> EF-hand_9 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.0 0.0021 4.5 2 43 .. 15 55 .. 14 73 .. 0.82 2 ! 7.8 0.0 0.003 6.4 3 25 .. 87 109 .. 86 127 .. 0.82 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0021 EF-hand_9 2 stFevcDtqktGeVpvskliayLravaaqdpqeleleelare 43 F+++D ++ G V+ ++l ++r + + + e+eel + FUN_001735-T1 15 ECFNLFDGDSDGMVTEKELGLIMRSLGE-NITHFEIEELMTK 55 56**********************9999.8888899988766 PP == domain 2 score: 7.8 bits; conditional E-value: 0.003 EF-hand_9 3 tFevcDtqktGeVpvskliayLr 25 F + D++ktG V s+l ++ FUN_001735-T1 87 AFTALDREKTGSVSRSQLQHLMT 109 699**********9999987765 PP >> WHD_MCM4 MCM4, winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 1.8 3.8e+03 29 56 .. 13 40 .. 6 45 .. 0.70 2 ! 9.7 0.0 0.00059 1.3 15 59 .. 50 94 .. 38 101 .. 0.76 3 ? 5.6 0.0 0.011 23 17 64 .. 90 135 .. 80 146 .] 0.71 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 1.8 WHD_MCM4 29 fnellkklnEqssvrVenselsealrrL 56 f+e ++ + s+ V ++el +r+L FUN_001735-T1 13 FKECFNLFDGDSDGMVTEKELGLIMRSL 40 6666666777777777777777777776 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00059 WHD_MCM4 15 lklldetssgnsirfnellkklnEqssvrVen.selsealrrLeqE 59 +l++ ++ ++++rf e lk l Eq + + + +e+ a +L +E FUN_001735-T1 50 EELMT-KAGKQKVRFPEFLKMLAEQTGKMISTeKEILAAFTALDRE 94 44555.57779**************999887524677777766665 PP == domain 3 score: 5.6 bits; conditional E-value: 0.011 WHD_MCM4 17 lldetssgnsirfnellkklnEqssvrVenselsealrrLeqEgkvvv 64 ld +++++s++ ++l + ++ ++ ++e++ lr L Eg+ + FUN_001735-T1 90 ALD-REKTGSVSRSQLQHLMTG-TGDKLGTEEFDHMLRDLGLEGSTSI 135 344.577778888888766655.7888999999999999999987554 PP >> EF-hand_FSTL1 Follistatin-related protein 1, EF-hand domain pair # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.7 0.1 0.00069 1.5 32 62 .. 8 38 .. 2 63 .. 0.74 2 ? 5.5 0.0 0.014 29 26 62 .. 73 109 .. 59 131 .. 0.75 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00069 EF-hand_FSTL1 32 syrellekyFkavDknkdkkldskEllelve 62 s+ + ++++F+ +D ++d+++ +kEl +++ FUN_001735-T1 8 SQIDEFKECFNLFDGDSDGMVTEKELGLIMR 38 5667899******************976665 PP == domain 2 score: 5.5 bits; conditional E-value: 0.014 EF-hand_FSTL1 26 llekgksyrellekyFkavDknkdkkldskEllelve 62 + k s ++ + F+a+D++k ++++++ l +l++ FUN_001735-T1 73 QTGKMISTEKEILAAFTALDREKTGSVSRSQLQHLMT 109 35677788999999**************999998887 PP >> EF-hand_11 EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.1 2.4e+03 66 84 .. 54 72 .. 14 81 .. 0.79 2 ? 15.3 0.0 1.8e-05 0.039 15 80 .. 77 142 .. 67 146 .] 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.1 EF-hand_11 66 pvnakgrlkyqdflsklsi 84 k ++++++fl l+ FUN_001735-T1 54 TKAGKQKVRFPEFLKMLAE 72 3445888999999987764 PP == domain 2 score: 15.3 bits; conditional E-value: 1.8e-05 EF-hand_11 15 vashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdfls 80 + s + i f +d k+ +vsr +++ + t + l e+fd + +l ++ ++y d++ FUN_001735-T1 77 MISTEKEILAAFTALDREKTGSVSRSQLQHLMTGTGDKLGTEEFDHMLRDLGLEGSTSIQYTDLVR 142 55667789999***************************************************9875 PP >> Ogg-HhH 8-oxoguanine DNA glycosylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 7.7e-05 0.16 41 126 .. 36 130 .. 8 143 .. 0.75 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 7.7e-05 Ogg-HhH 41 aqkelgeegllklseeeleekLkelghrfkn.......kkaeyivearelleklkkiikekedeleaRellvknikGlgyK....EasHfLRNvGf 125 ++++lg e++++ + eel +k + ++rf++ + + i + +e+l + ++++++ R+ l + ++G g K E H+LR +G+ FUN_001735-T1 36 IMRSLG-ENITHFEIEELMTKAGKQKVRFPEflkmlaeQTGKMISTEKEILAAF-TALDREKTGSVSRSQLQHLMTGTGDKlgteEFDHMLRDLGL 129 677888.899999*********999****8622222213344444444444333.334447888899999999999976554444999*******9 PP Ogg-HhH 126 e 126 e FUN_001735-T1 130 E 130 5 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (146 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 817 (0.0319828); expected 510.9 (0.02) Passed bias filter: 672 (0.0263065); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1467.11 // Query: FUN_001736-T1 [L=856] Description: FUN_001736 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.8 9.0 13.8 1.4e+02 2.9 0.1 6.1 6 DUF1502 Repeat of unknown function (DUF1502) Domain annotation for each model (and alignments): >> DUF1502 Repeat of unknown function (DUF1502) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 0.057 1.5e+03 15 24 .. 543 552 .. 541 555 .. 0.71 2 ? 2.9 0.1 0.0056 1.4e+02 8 15 .. 585 592 .. 575 604 .. 0.84 3 ? 2.5 0.0 0.0074 1.9e+02 8 15 .. 627 634 .. 625 646 .. 0.87 4 ? 1.8 0.4 0.012 3.1e+02 8 15 .. 753 760 .. 752 763 .. 0.88 5 ? 2.4 0.0 0.0078 2e+02 8 15 .. 791 798 .. 789 808 .. 0.88 6 ? 2.2 0.1 0.0094 2.4e+02 8 15 .. 833 840 .. 832 846 .. 0.87 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.057 DUF1502 15 PAWGAkarrr 24 PA G ++rr+ FUN_001736-T1 543 PAQGSGPRRK 552 6677777765 PP == domain 2 score: 2.9 bits; conditional E-value: 0.0056 DUF1502 8 PARGAGPP 15 PA G GPP FUN_001736-T1 585 PAQGSGPP 592 89999999 PP == domain 3 score: 2.5 bits; conditional E-value: 0.0074 DUF1502 8 PARGAGPP 15 PA G GPP FUN_001736-T1 627 PAQGSGPP 634 89999999 PP == domain 4 score: 1.8 bits; conditional E-value: 0.012 DUF1502 8 PARGAGPP 15 PA G GPP FUN_001736-T1 753 PAQGSGPP 760 99999999 PP == domain 5 score: 2.4 bits; conditional E-value: 0.0078 DUF1502 8 PARGAGPP 15 PA G GPP FUN_001736-T1 791 PAQGSGPP 798 89999999 PP == domain 6 score: 2.2 bits; conditional E-value: 0.0094 DUF1502 8 PARGAGPP 15 PA G GPP FUN_001736-T1 833 PAQGSGPP 840 89999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (856 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1780 (0.069681); expected 510.9 (0.02) Passed bias filter: 468 (0.0183206); expected 510.9 (0.02) Passed Vit filter: 97 (0.00379722); expected 25.5 (0.001) Passed Fwd filter: 37 (0.00144842); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.61u 0.35s 00:00:00.96 Elapsed: 00:00:00.42 # Mc/sec: 8178.67 // Query: FUN_001737-T1 [L=224] Description: FUN_001737 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-27 96.6 2.4 2.2e-27 96.6 2.4 1.6 2 Serinc Serine incorporator (Serinc) ------ inclusion threshold ------ 0.013 16.0 0.0 0.024 15.2 0.0 1.4 1 CCD WisP family C-Terminal Region 0.51 10.8 3.8 0.59 10.6 0.0 2.7 3 FtsL_2 Bacteriodetes cell division protein (FtsL-li 1.1 10.0 3.5 8.5 7.1 0.6 2.8 2 TolA_bind_tri TolA binding protein trimerisation 2.5 8.6 8.4 1.3 9.4 2.5 2.2 2 Ax_dynein_light Axonemal dynein light chain Domain annotation for each model (and alignments): >> Serinc Serine incorporator (Serinc) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.6 2.4 4.3e-31 2.2e-27 349 430 .. 20 101 .. 2 104 .. 0.86 2 ? -3.3 2.2 0.89 4.5e+03 321 361 .. 128 179 .. 109 184 .. 0.38 Alignments for each domain: == domain 1 score: 96.6 bits; conditional E-value: 4.3e-31 Serinc 349 eeekkkakddekegvkYsYsfFHlifflaslYvamlLTnwvspeeakdfakvgrswaavWvkivssWvclllYlWtLvAPlv 430 ++++++ +++ e+v+Y+Ys+F +i+fla+lY++m+LTnw+sp++a+d ++++rsw+avW+k+ ss +cl+lY+W L+AP++ FUN_001737-T1 20 KSSDAECREKTVEEVAYNYSLFTFIIFLATLYIMMTLTNWYSPTQATDISRLERSWPAVWIKMGSSSACLCLYIWKLLAPVF 101 33345677888899******************************************************************97 PP == domain 2 score: -3.3 bits; conditional E-value: 0.89 Serinc 321 eqeeekeelraealkeaveegslpesa..leee...........kkkakddeke 361 +++e++++++ + ++av++++l++++ l + +k+++++ek+ FUN_001737-T1 128 SSKETSNTVNDVKPERAVSNQDLKKKRhtL--HgnletqyhetpTKRNIEKEKQ 179 222222223333333333333333333220..1112222222334555555554 PP >> CCD WisP family C-Terminal Region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 4.7e-06 0.024 24 96 .. 77 150 .. 63 161 .. 0.84 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 4.7e-06 CCD 24 gfwskvgsgiaapfkwiwhgitwpfrklfgsrseapsst.tnatgntsgktrvkrdtpttppehplksvndqit 96 +w k+gs a+ +iw+ ++ fr +f +e+ + g+t k + t +p ++v +q FUN_001737-T1 77 AVWIKMGSSSACLCLYIWKLLAPVFRSMFEGDTESSAIQsHGVRGQTNCEQSSKETSNTVNDVKPERAVSNQDL 150 68***************************998887765404567999999999999999999999999988754 PP >> FtsL_2 Bacteriodetes cell division protein (FtsL-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.00011 0.59 17 50 .. 40 73 .. 27 85 .. 0.85 2 ? -1.8 0.2 0.8 4.1e+03 61 61 .. 156 156 .. 119 186 .. 0.57 3 ? 0.2 0.1 0.2 1e+03 42 56 .. 206 220 .. 193 221 .. 0.83 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00011 FtsL_2 17 nwrfilFlvlLallmIanshsaekkvreiaklnk 50 +fi+Fl++L ++m + + + +i++l++ FUN_001737-T1 40 LFTFIIFLATLYIMMTLTNWYSPTQATDISRLER 73 4689999999999999999999999999999987 PP == domain 2 score: -1.8 bits; conditional E-value: 0.8 FtsL_2 61 d 61 + FUN_001737-T1 156 T 156 1 PP == domain 3 score: 0.2 bits; conditional E-value: 0.2 FtsL_2 42 vreiaklnkevkelr 56 +iakl+ +v el+ FUN_001737-T1 206 QEKIAKLQHKVAELQ 220 578999999999985 PP >> TolA_bind_tri TolA binding protein trimerisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.1 0.11 5.7e+02 28 47 .. 148 167 .. 146 173 .. 0.87 2 ? 7.1 0.6 0.0017 8.5 20 40 .. 202 222 .. 197 223 .. 0.88 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.11 TolA_bind_tri 28 eqLqqevaeLRGqiEelqyq 47 ++L++ L+G +E + ++ FUN_001737-T1 148 QDLKKKRHTLHGNLETQYHE 167 688899999********998 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0017 TolA_bind_tri 20 llelqqqleqLqqevaeLRGq 40 l+lq+++ +Lq+ vaeL+G FUN_001737-T1 202 VLRLQEKIAKLQHKVAELQGL 222 578****************96 PP >> Ax_dynein_light Axonemal dynein light chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 2.5 0.00026 1.3 108 172 .. 116 184 .. 108 187 .. 0.86 2 ? 2.5 0.3 0.036 1.9e+02 119 146 .. 193 220 .. 187 223 .. 0.58 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00026 Ax_dynein_light 108 aFgvrkalqaeqgkaelekkikeLeee....keeLekevaelkakleelekreeeerqeeekkhaeeia 172 +gvr +++ eq ++e+++++++++ e +++L+k+ ++l+ +le+ ++ ++r++e++k+a+ ia FUN_001737-T1 116 SHGVRGQTNCEQSSKETSNTVNDVKPEravsNQDLKKKRHTLHGNLETQYHETPTKRNIEKEKQATSIA 184 69*********************98653333789999999*******9999999999999999998875 PP == domain 2 score: 2.5 bits; conditional E-value: 0.036 Ax_dynein_light 119 qgkaelekkikeLeeekeeLekevaelk 146 ++ +l+ k+ +L+e+ ++L+++vael+ FUN_001737-T1 193 KEVLRLQGKVLRLQEKIAKLQHKVAELQ 220 4444455555566666666666666654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1661 (0.0650225); expected 510.9 (0.02) Passed bias filter: 776 (0.0303778); expected 510.9 (0.02) Passed Vit filter: 98 (0.00383637); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2220.59 // Query: FUN_001738-T1 [L=144] Description: FUN_001738 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-26 91.6 5.5 8.3e-26 91.4 5.5 1.0 1 Serinc Serine incorporator (Serinc) ------ inclusion threshold ------ 0.067 13.3 1.6 0.067 13.3 1.6 2.0 2 Tetraspanin Tetraspanin family Domain annotation for each model (and alignments): >> Serinc Serine incorporator (Serinc) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 91.4 5.5 6.5e-30 8.3e-26 8 124 .. 15 131 .. 11 143 .. 0.89 Alignments for each domain: == domain 1 score: 91.4 bits; conditional E-value: 6.5e-30 Serinc 8 acsllcsccpsiksstatRlaYalllllnslvswimlsptvekkleklslkiiksCe.ekaseece...gvlaVyRvcfalalfflllallligvk 99 a +lc +c++ik t+tR+ Y+++lll++++++++ p +++k++ i++ C+ + ++c+ g + VyRvcfa+a+f+++ +++++gvk FUN_001738-T1 15 ATFCLCGVCGKIKRATVTRVNYTMFLLLVTVLCFLLSFPRARTKIN----AIPHLCDeLVSAQTCDnltGHTGVYRVCFATAIFYFVASCVVVGVK 106 334699****************************************....7788899845556666666*************************** PP Serinc 100 sskdpraaiqnGfWflKillllalv 124 + + r++i+nGfW +K+l+l++ FUN_001738-T1 107 NVGEFRSKIHNGFWYIKFLVLIGQS 131 *********************9865 PP >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 1.6 5.2e-06 0.067 60 94 .. 17 51 .. 14 58 .. 0.92 2 ? 1.9 0.2 0.016 2.1e+02 5 41 .. 88 117 .. 72 135 .. 0.61 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 5.2e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 60 vgflGccgalkesrcllllyfvlllllflaelaag 94 ++++G+cg +k+ ++ + y ++lll+ ++++ ++ FUN_001738-T1 17 FCLCGVCGKIKRATVTRVNYTMFLLLVTVLCFLLS 51 799**************************999875 PP == domain 2 score: 1.9 bits; conditional E-value: 0.016 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 5 lfllnllflllGllllavGvwlksleaassalsesse 41 f++ ++ +++++++++v ++ s+ + FUN_001738-T1 88 CFATAIFYFVASCVVVGVK-------NVGEFRSKIHN 117 4666677777777777774.......22223333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 999 (0.0391075); expected 510.9 (0.02) Passed bias filter: 509 (0.0199256); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.35s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 1500.79 // Query: FUN_001739-T1 [L=509] Description: FUN_001739 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-72 245.5 6.9 1.4e-72 245.5 6.9 1.8 2 Serinc Serine incorporator (Serinc) ------ inclusion threshold ------ 0.12 12.4 1.7 1.8 8.5 1.1 2.2 2 DUF1295 Protein of unknown function (DUF1295) Domain annotation for each model (and alignments): >> Serinc Serine incorporator (Serinc) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 245.5 6.9 1.1e-76 1.4e-72 176 430 .. 5 263 .. 1 266 [. 0.88 2 ? -3.4 3.1 0.38 4.8e+03 311 347 .. 309 342 .. 283 368 .. 0.52 Alignments for each domain: == domain 1 score: 245.5 bits; conditional E-value: 1.1e-76 Serinc 176 esklwkaaLlvvtlllyalaialtvllyvfftksg....CslnkffislnlilcvlvsvvsilpkvqeanprsgLlqssvvslYvtYLtlsAlsse 267 + k+w++ L+++t+++y+l+++++v++y+fft+++ C+ n+f is+n+ c l++++s+lp+vqe + +gLlqssv+++Y++YLt+ lss+ FUN_001739-T1 5 DTKCWYFSLAFSTAFVYSLSVTAAVMFYLFFTNPDdisqCQANTFYISFNVGHCALATIISVLPRVQEETTGAGLLQSSVITIYTMYLTWNTLSSQ 100 789******************************988999********************************************************* PP Serinc 268 pddkecnpllrss...egtr....tasvvlgalltflavlYstlraasnsallklkksveeqeeekeelraealkeaveegslpesa.leeekkka 355 p d++cnpl + + + + ++++gall+f ++++++ as s+l kl s +++ e lr +a ++a++ +++a le+ +k+ FUN_001739-T1 101 P-DSKCNPLGEVLleyD--KisgvNGQAIFGALLMFSLLAFACTVRASTSQLGKLGLSLSDS---PEYLRKSAETNAKHR--KEDKAlLEKGGKEG 188 *.9******99986552..1346799********************************3333...333443333333333..22222144446788 PP Serinc 356 kddekegvkYsYsfFHlifflaslYvamlLTnwvspeeakdfakvgrswaavWvkivssWvclllYlWtLvAPlv 430 +++e e +YsYsfFH+++flasl+v+m++Tnw sp+e+ df+k+ ++waavWv+++ss++c+l+Y+WtLvAPl+ FUN_001739-T1 189 EEKECEDIAYSYSFFHFVLFLASLHVMMVMTNWHSPDENLDFKKMIKNWAAVWVQMASSYICCLVYIWTLVAPLI 263 9999999******************************999*********************************98 PP == domain 2 score: -3.4 bits; conditional E-value: 0.38 Serinc 311 allklkksveeqeeekeelraealkeaveegslpesa 347 a+ ++ v++q e+++++r +l+ea+++ s ++++ FUN_001739-T1 309 AARAK---VTQQVEKESKVRKRHLQEASKTPSKNHND 342 22222...33455555555555555555553333333 PP >> DUF1295 Protein of unknown function (DUF1295) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.015 1.9e+02 180 214 .. 111 145 .. 105 162 .. 0.84 2 ? 8.5 1.1 0.00014 1.8 51 108 .. 209 265 .. 200 271 .. 0.85 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.015 DUF1295 180 flialealeglealtilgpllltlllvfvsgipll 214 +l+ +++g++ +i+g+ll++ ll f ++ FUN_001739-T1 111 VLLEYDKISGVNGQAIFGALLMFSLLAFACTVRAS 145 67777888999999**************9999865 PP == domain 2 score: 8.5 bits; conditional E-value: 0.00014 DUF1295 51 glRLalhllrrilkkg.eDkryeelrkelgktvallkllivfvlQavlllivslpvlla 108 + L + +++ +++++ e +++++k++ + ++ ++++ +++ v++++++ p++ + FUN_001739-T1 209 LASLHVMMVMTNWHSPdENLDFKKMIKNWAAVWV--QMASSYICCLVYIWTLVAPLIRS 265 56788999999*****999**********97766..58899999999999999999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (509 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2222 (0.0869838); expected 510.9 (0.02) Passed bias filter: 980 (0.0383637); expected 510.9 (0.02) Passed Vit filter: 88 (0.0034449); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 4839.28 // Query: FUN_001740-T1 [L=335] Description: FUN_001740 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-06 27.1 1.5 9.5e-06 25.9 1.5 1.7 1 PAN_1 PAN domain 0.006 17.1 0.8 0.024 15.1 0.8 2.1 1 PAN_4 PAN domain ------ inclusion threshold ------ 0.29 11.5 4.0 0.15 12.4 1.2 2.0 2 PAN_3 PAN-like domain Domain annotation for each model (and alignments): >> PAN_1 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 1.5 1.1e-09 9.5e-06 3 59 .. 19 78 .. 17 92 .. 0.77 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 1.1e-09 PAN_1 3 fervpgsslegedkktv.tvssaeeCaqrCaeekrCrsftYnekskkCllksessgs...s 59 +++++ l g++ + +v + C+q C e++C s++Y++++k C ++s+ + + FUN_001740-T1 19 CTTYEDRYLPGNSLRISwDV-DWMGCLQICHGEPNCISYNYHKDKKICKINSDGEKEdcgT 78 56788888888555555599.9999**************************9987765543 PP >> PAN_4 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.8 2.9e-06 0.024 15 40 .. 37 63 .. 25 77 .. 0.76 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 2.9e-06 PAN_4 15 vdspeaCcaaCdedprCnawvfvkp.g 40 ++ C + C+ +p+C ++ ++k+ + FUN_001740-T1 37 DVDWMGCLQICHGEPNCISYNYHKDkK 63 46899*******************751 PP >> PAN_3 PAN-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 1.2 1.8e-05 0.15 20 45 .. 38 65 .. 34 72 .. 0.78 2 ? -2.4 0.1 0.76 6.5e+03 21 51 .. 256 286 .. 247 299 .. 0.74 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.8e-05 PAN_3 20 eswdeCvtkCledetCvlaykn..senC 45 ++w C++ C+++ +C+ + ++ C FUN_001740-T1 38 VDWMGCLQICHGEPNCISYNYHkdKKIC 65 68**************964333245556 PP == domain 2 score: -2.4 bits; conditional E-value: 0.76 PAN_3 21 swdeCvtkCledetCvlayknsenCqlfeig 51 +w + +++ + +etC + + ++ +l++++ FUN_001740-T1 256 DWTSLINNSFVNETCSRSVTTYQGFNLHKYD 286 5666667777778887777777777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (335 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 826 (0.0323351); expected 510.9 (0.02) Passed bias filter: 568 (0.0222353); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3292.53 // Query: FUN_001741-T1 [L=821] Description: FUN_001741 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (821 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1244 (0.0486984); expected 510.9 (0.02) Passed bias filter: 510 (0.0199648); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.36u 0.43s 00:00:00.79 Elapsed: 00:00:00.41 # Mc/sec: 8046.07 // Query: FUN_001742-T1 [L=200] Description: FUN_001742 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-15 57.5 2.6 2.4e-15 56.9 2.6 1.3 1 CD225 Interferon-induced transmembrane protein ------ inclusion threshold ------ 9.4 7.1 11.6 0.14 13.0 1.0 2.3 2 DUF4620 Domain of unknown function (DUF4620) Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.9 2.6 1.9e-19 2.4e-15 2 66 .. 124 188 .. 123 190 .. 0.96 Alignments for each domain: == domain 1 score: 56.9 bits; conditional E-value: 1.9e-19 CD225 2 PkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviii 66 P+d+ ++++f++l+c++p+Gi+A++ S++v a+ d++ A+ as Ak++++i++ +g +i+ FUN_001742-T1 124 PEDHKILAWFACLCCFCPVGILAIIRSSQVHTHLARSDVNSARIASAGAKKYALIAISIGTSFIA 188 89**********************************************************98876 PP >> DUF4620 Domain of unknown function (DUF4620) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 3.6 0.32 4.1e+03 16 46 .. 20 50 .. 11 80 .. 0.69 2 ? 13.0 1.0 1.1e-05 0.14 56 82 .. 121 147 .. 93 161 .. 0.77 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.32 DUF4620 16 pdrwtgtpgwpsrdqeapgsmmppaaaqpsa 46 p ++t + g s + ap pp + qps FUN_001742-T1 20 PPKYTSAGGVESPNPSAPPLPPPPYTEQPSY 50 5567777777777777777777777777763 PP == domain 2 score: 13.0 bits; conditional E-value: 1.1e-05 DUF4620 56 ahepvdhpalhwlacccclslpgqlpl 82 + p dh l w+ac cc++ g l + FUN_001742-T1 121 TTIPEDHKILAWFACLCCFCPVGILAI 147 44689*************998887654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (200 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 660 (0.0258368); expected 510.9 (0.02) Passed bias filter: 410 (0.0160501); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 2050.71 // Query: FUN_001743-T1 [L=204] Description: FUN_001743 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-18 64.8 1.2 1.3e-17 64.2 1.2 1.3 1 CD225 Interferon-induced transmembrane protein Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.2 1.2 5.1e-22 1.3e-17 2 67 .. 123 188 .. 122 189 .. 0.98 Alignments for each domain: == domain 1 score: 64.2 bits; conditional E-value: 5.1e-22 CD225 2 PkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviiil 67 P+d+ +++++++l+c++p+Gi+A+++S +v a+Gd++ A+ as +Ak++++ ++++g ++++l FUN_001743-T1 123 PEDHCMLAWCACLCCFCPIGIIAVIKSNQVHTHLARGDVNSARIASTEAKKYAHRAICFGTTFFVL 188 99************************************************************9987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (204 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1017 (0.0398121); expected 510.9 (0.02) Passed bias filter: 557 (0.0218047); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2026.27 // Query: FUN_001744-T1 [L=203] Description: FUN_001744 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-20 72.2 3.3 5.9e-20 71.7 3.3 1.2 1 CD225 Interferon-induced transmembrane protein ------ inclusion threshold ------ 4.4 8.2 7.9 0.15 13.0 1.0 2.0 2 DUF4620 Domain of unknown function (DUF4620) Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.7 3.3 4.6e-24 5.9e-20 2 67 .. 123 188 .. 122 189 .. 0.97 Alignments for each domain: == domain 1 score: 71.7 bits; conditional E-value: 4.6e-24 CD225 2 PkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviiil 67 P+d+ ++++f++l+c++p+Gi+A+++S +v++ a+Gd++ A+ as +Ak++++i++++g +++++ FUN_001744-T1 123 PEDHCMLAWFACLCCFWPVGIIAVIKSNQVQSHLARGDVNSARIASAEAKKYALIAVCIGAALFVF 188 99************************************************************9986 PP >> DUF4620 Domain of unknown function (DUF4620) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 1.2 0.23 2.9e+03 17 44 .. 20 47 .. 10 107 .. 0.66 2 ? 13.0 1.0 1.1e-05 0.15 41 79 .. 105 143 .. 71 174 .. 0.76 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.23 DUF4620 17 drwtgtpgwpsrdqeapgsmmppaaaqp 44 ++t t g s a pp + qp FUN_001744-T1 20 PKYTSTGGVDSPHPSAAPLPPPPYTEQP 47 4555555555555554444444555554 PP == domain 2 score: 13.0 bits; conditional E-value: 1.1e-05 DUF4620 41 aaqpsahgalvppatahepvdhpalhwlacccclslpgq 79 + qp p + p dh l w+ac cc+ g FUN_001744-T1 105 TGQPGNTIMRQPVQLTTIPEDHCMLAWFACLCCFWPVGI 143 557777666777778889***************865555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 820 (0.0321002); expected 510.9 (0.02) Passed bias filter: 600 (0.023488); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.43s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2017.52 // Query: FUN_001745-T1 [L=920] Description: FUN_001745 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.042 14.4 2.4 14 6.3 0.3 3.7 4 Type_III_YscG Bacterial type III secretion system chaperone 0.058 14.1 0.0 20 6.0 0.0 2.7 2 GLGE_C GLGE, C-terminal 0.061 14.1 4.2 19 6.1 0.1 3.5 3 OMP10 Outer membrane lipoprotein Omp10 6.4 7.1 6.3 36 4.7 1.3 2.8 3 Rv3651-like_C Rv3651-like, C-terminal domain Domain annotation for each model (and alignments): >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.3 0.0022 14 11 41 .. 186 216 .. 176 232 .. 0.68 2 ? -0.8 0.0 0.34 2.2e+03 12 30 .. 241 259 .. 232 277 .. 0.74 3 ? 3.9 0.1 0.012 75 14 56 .. 261 304 .. 253 313 .. 0.67 4 ? 2.1 0.0 0.045 2.8e+02 14 38 .. 279 303 .. 273 328 .. 0.79 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0022 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgeeeaa 41 + lv G h +ean+i+ l +g+ FUN_001745-T1 186 SLDLVADGTHTGNEANCISSDLIGNGNSAGN 216 5778888999999999998877766665333 PP == domain 2 score: -0.8 bits; conditional E-value: 0.34 Type_III_YscG 12 ialvGsGqhcheeaniiae 30 + l+ G+ +ean+i+ FUN_001745-T1 241 LDLIAIGNPTGNEANCISL 259 6788899999999999974 PP == domain 3 score: 3.9 bits; conditional E-value: 0.012 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkgeeeaarlirlss.lanqGkyq 56 l+ + +ean+i+ l ++g+ + +ss l+ +G+y FUN_001745-T1 261 LIADVNSTGNEANCISSDLISNGNSTGNEANCISSdLISNGNYT 304 66666677778888888887777775544444444377777775 PP == domain 4 score: 2.1 bits; conditional E-value: 0.045 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkgee 38 l+ G+ +ean+i+ l ++g+ FUN_001745-T1 279 LISNGNSTGNEANCISSDLISNGNY 303 8999***********9999887764 PP >> GLGE_C GLGE, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.0031 20 56 80 .. 168 192 .. 155 196 .. 0.83 2 ? 5.0 0.0 0.0061 39 51 76 .. 289 314 .. 257 317 .. 0.75 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0031 GLGE_C 56 vhDlltgeeyeWgeenyVrLdpeke 80 +Dl+t +y+ +e+nyV+Ld ++ FUN_001745-T1 168 SQDLITSGNYTGNEANYVSLDLVAD 192 58******************97665 PP == domain 2 score: 5.0 bits; conditional E-value: 0.0061 GLGE_C 51 eesfevhDlltgeeyeWgeenyVrLd 76 e+++ +Dl+++ +y+ +e nyV+Ld FUN_001745-T1 289 EANCISSDLISNGNYTRNEVNYVSLD 314 4456679*****************98 PP >> OMP10 Outer membrane lipoprotein Omp10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.1 0.003 19 28 62 .. 169 203 .. 162 208 .. 0.89 2 ? 2.8 0.2 0.031 2e+02 17 62 .. 228 275 .. 211 290 .. 0.75 3 ? 4.7 0.4 0.0081 52 16 60 .. 281 327 .. 270 329 .. 0.79 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.003 OMP10 28 gekLaeGtYtktsaklveieltslvrktqskvnCa 62 ++ +++G+Yt ++a+ v+++l ++t ++nC FUN_001745-T1 169 QDLITSGNYTGNEANYVSLDLVADGTHTGNEANCI 203 66789*****************************6 PP == domain 2 score: 2.8 bits; conditional E-value: 0.031 OMP10 17 nGrFetratd..tgekLaeGtYtktsaklveieltslvrktqskvnCa 62 +G+ + ++++ + + +a G+ t ++a+ ++++l v+ t ++nC FUN_001745-T1 228 DGNHNGNEANyeSLDLIAIGNPTGNEANCISLDLIADVNSTGNEANCI 275 455555544422445788888888999999999999999999999995 PP == domain 3 score: 4.7 bits; conditional E-value: 0.0081 OMP10 16 snGrFetratd..tgekLaeGtYtktsaklveieltslvrktqskvn 60 snG+ + ++++ + + +++G+Yt+++ + v+++l + ++t ++n FUN_001745-T1 281 SNGNSTGNEANciSSDLISNGNYTRNEVNYVSLDLIAIGNQTGNEAN 327 566666666665567799******************99999987776 PP >> Rv3651-like_C Rv3651-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.1 0.01 64 22 51 .. 539 568 .. 533 605 .. 0.71 2 ? 4.7 1.3 0.0056 36 27 56 .. 606 634 .. 602 643 .. 0.80 3 ? -3.4 0.0 1.8 1.1e+04 15 27 .. 665 677 .. 662 699 .. 0.76 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.01 Rv3651-like_C 22 dlkswkllkwldepcPfldwraeekeesvv 51 d sw++ k ld+ +l+wr ++ + + FUN_001745-T1 539 DDSSWNFAKLLDHCNEYLNWRRSSDVSLRT 568 7789*****************987555444 PP == domain 2 score: 4.7 bits; conditional E-value: 0.0056 Rv3651-like_C 27 kllkwldepcPfldwraeekeesvvhPdde 56 ++ kw ++ P+l+wr ++ + + +P+d+ FUN_001745-T1 606 RITKWWNNCWPYLEWRKSNVSV-QTDPQDN 634 678*************999654.5678775 PP == domain 3 score: -3.4 bits; conditional E-value: 1.8 Rv3651-like_C 15 gvhralvdlkswk 27 +++ +vd+k w FUN_001745-T1 665 NIYHKIVDIKRWI 677 6889999**9995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (920 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1586 (0.0620865); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.46u 0.41s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 8568.00 // Query: FUN_001746-T1 [L=256] Description: FUN_001746 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-16 59.5 0.2 6.6e-16 58.7 0.2 1.4 1 CD225 Interferon-induced transmembrane protein ------ inclusion threshold ------ 0.11 13.0 1.6 0.14 12.7 1.6 1.1 1 LicD LicD family 0.17 12.6 0.9 0.27 12.0 0.9 1.2 1 DRY_EERY Alternative splicing regulator 0.2 11.4 0.5 0.25 11.1 0.5 1.1 1 Cas_Csa4 CRISPR-associated protein (Cas_Csa4) 0.69 10.8 4.2 0.38 11.6 0.9 2.0 2 DUF4620 Domain of unknown function (DUF4620) Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.7 0.2 1.3e-19 6.6e-16 1 51 [. 105 155 .. 105 158 .. 0.97 Alignments for each domain: == domain 1 score: 58.7 bits; conditional E-value: 1.3e-19 CD225 1 pPkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAk 51 +P+d+ ++++f++l+c++p+Gi+A+ +S++v++ a+Gd++ A+ as Ak FUN_001746-T1 105 MPEDHSILAWFACLCCFWPVGIIAVLKSTQVQSHLARGDVNSARIASADAK 155 599***********************************************9 PP >> LicD LicD family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 1.6 2.8e-05 0.14 78 155 .. 150 228 .. 132 253 .. 0.64 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.8e-05 LicD 78 tsrengngkndvdsglfiDIfpldyvpdskelklkskkekekllkklklk.ealsssdksellkklllkkksfklkelk 155 s + +n++ ++ glf DI ld+v + e + s+k k+++l++ ++ ++++++ +++l+k+++ k+s+k+k+ + FUN_001746-T1 150 ASADAKNNHPTFELGLFDDIQELDNVSEMVETSETSDKSKDQQLSESATGeNNRFANLSERDLEKIIEDKESKKTKKNT 228 344444445589************9997655443333333333333333357777777788888887777766655433 PP >> DRY_EERY Alternative splicing regulator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.9 5.3e-05 0.27 45 106 .. 170 232 .. 157 250 .. 0.76 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.3e-05 DRY_EERY 45 alLddipeaekeesarlsekseeeeeeeeelneERYrdLikneeeevseeeelkrlaeeee..a 106 + Ld+++e+ + s++++++++++ +e++ + R+ L + + e++ e++e k+++++++ FUN_001746-T1 170 QELDNVSEMVE-TSETSDKSKDQQLSESATGENNRFANLSERDLEKIIEDKESKKTKKNTNwcV 232 56788888876.456666667777777888999**********************999877532 PP >> Cas_Csa4 CRISPR-associated protein (Cas_Csa4) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.5 4.9e-05 0.25 46 115 .. 151 227 .. 129 251 .. 0.76 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 4.9e-05 Cas_Csa4 46 evdvrnkn..lekgLrealeevlslhealgrr....kiisdadisagafisdlqnlnrvy.relesilnnle..klkas 115 ++d++n++ +e gL++ +e+ + e + + + d ++s +a + ++ ++++ r le+i+++ e k+k+ FUN_001746-T1 151 SADAKNNHptFELGLFDDIQELDNVSEMV-ETsetsDKSKDQQLSESA-TGENNRFANLSeRDLEKIIEDKEskKTKKN 227 48899988999999999988885555533.333666777899******.677789999999*******99995333333 PP >> DUF4620 Domain of unknown function (DUF4620) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.1 0.47 2.4e+03 7 28 .. 29 50 .. 16 69 .. 0.71 2 ? 11.6 0.9 7.4e-05 0.38 51 76 .. 98 123 .. 67 142 .. 0.76 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.47 DUF4620 7 lssqsgveppdrwtgtpgwpsr 28 ++sq e p +t p +p + FUN_001746-T1 29 VASQHPSELPPSYTEQPSYPMH 50 4566667777777777777754 PP == domain 2 score: 11.6 bits; conditional E-value: 7.4e-05 DUF4620 51 vppatahepvdhpalhwlacccclsl 76 + + p dh l w+ac cc+ FUN_001746-T1 98 LSSQDTTMPEDHSILAWFACLCCFWP 123 4445566799*************865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (256 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1730 (0.0677236); expected 510.9 (0.02) Passed bias filter: 852 (0.0333529); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2504.82 // Query: FUN_001747-T1 [L=653] Description: FUN_001747 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-48 163.6 10.1 2.1e-38 132.8 0.5 2.5 2 LolA_2nd_metazoa Metazoan 2nd LolA-like domain 3.8e-12 46.5 0.2 8.3e-12 45.4 0.2 1.5 1 DUF7959 Domain of unknown function (DUF7959) Domain annotation for each model (and alignments): >> LolA_2nd_metazoa Metazoan 2nd LolA-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.2 3.6 2.2e-12 2.8e-08 13 217 .. 35 228 .. 23 237 .. 0.73 2 ! 132.8 0.5 1.6e-42 2.1e-38 1 227 [] 238 461 .. 238 461 .. 0.81 Alignments for each domain: == domain 1 score: 34.2 bits; conditional E-value: 2.2e-12 LolA_2nd_metazoa 13 kplpklpdaFsfsveivdsesktvsyideyYdkknklvrydlrpdsdkdlpfvseatlkkgtdpvteihDFntGvaYiidketgnCsvepiss 105 +lp+lp+aFs+ v+ + e++ ++ e Yd+k +r +++ + t i D++ + +i+ + +nC+v+ + FUN_001747-T1 35 PKLPDLPTAFSTFVQATFAEKNYTAIFFESYDQKADKGL-LYRVRDG---------------IKHTDIYDYTL--EEVIHIDGNNCTVSSTNH 109 67999************9999999999999998875443.3334222...............45899999985..557888899****98888 PP LolA_2nd_metazoa 106 dsfdaeksnnshvrlkspkelffnlddsnftYvGkrkvrgidcdvwigkrtdskganstvewyFltdnwtee......nsegev.lhsivqyv 191 + + + ++ s +lf ++ n tY G vrgi c+ w + + + ++ v++yF+ +w ++ + + v s+ + FUN_001747-T1 110 TEPGHFNFFGRGPHIESVAKLFKFGKEYNETYIGISDVRGIRCHHWRSCISRN-HFSFHVDYYFTVPEWRTPrsmlnsTVVRAVvNGSFPAHS 201 887777777779*********977777999****************9988877.789**************9998866333333322222222 PP LolA_2nd_metazoa 192 knksnke..ketsievynfynfdeeeps 217 +++ +++ ++ +++++n+y+f + +p FUN_001747-T1 202 YRN-GTQvqTNGTTKFFNVYDFMDFQPG 228 222.222236666666776666655554 PP == domain 2 score: 132.8 bits; conditional E-value: 1.6e-42 LolA_2nd_metazoa 1 psgvyCpgrkst.kplpklpdaFsfsveivdsesktvsyideyYdkknklvrydlrpdsdkdlpfvseatlkkgtdpvteihDFntGvaYiid 92 p+gvyC+g+k + k++pk+p F +++e++ ++ ++v + +e Yd +klv ++p++ k +t+++ +i DFntG+ Y+i FUN_001747-T1 238 PEGVYCEGYKGSnKTVPKMPHVFALDFEFTGNHYNVVISWQETYDVGKKLVA-VMHPNYW-----------KPKTGAILTIEDFNTGIGYNIT 318 89********777**************************************9.5666443...........33789***************** PP LolA_2nd_metazoa 93 ketg..nCsvepissdsfdaeksnnshvrlkspkelff....nlddsnftYvGkrkvrgidcdvwigkrtd...skganstvewyFltdnwte 176 ++ g +Cs +i+++s a +++n+h+r+k+ +elf ++ +s ++Y+G+ vrgi++d+w+gkr +k +++++ewyF++ nw FUN_001747-T1 319 NYLGssTCSLYNITQRSMGAAEDENHHIRMKTTQELFGgspgKNGSSMLVYKGSASVRGINADIWMGKRVFkrnNKSHEAIMEWYFAKPNWRI 411 **77559*********9999999999**********9633323345779******************984434377788************** PP LolA_2nd_metazoa 177 e.....nsegevlhsivqyvknksnkeketsievynfynfdeeepslsefdissCf 227 e + +v+ ++v ++++ +++++v+nf n ++ ++fdi++Cf FUN_001747-T1 412 EsigysGIQYQVPLKVVFFTERG-----QNTMSVFNF-NPVVFATEPRVFDIKPCF 461 97665444445565555554444.....344555554.444556699********8 PP >> DUF7959 Domain of unknown function (DUF7959) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.4 0.2 6.5e-16 8.3e-12 8 106 .. 474 573 .. 468 581 .. 0.89 Alignments for each domain: == domain 1 score: 45.4 bits; conditional E-value: 6.5e-16 DUF7959 8 knkslkdlkevglenvekalaeaiakvanvSplRisnfyleq.sdekllvfFrlaeksgvkpantagykkElslaeavelLnktiksgeikikvet 102 ++ + k ++ + + + +l +a+++ anvS +R++++++ + ++e+l+v F ++e+ + +++ + +E+ l+e ++Ln+++++g++k + + FUN_001747-T1 474 NDPKGKHMNFADSNAFLLSLTKAVSNFANVSFIRVNKIQVLEyKKEELVVSFVMLERPKTTGSSLFVVYPENGLMEGLDALNDSVNHGKFKAEFQG 569 555566777788999999**********************99888*******************99999**********************99988 PP DUF7959 103 kdgk 106 ++ + FUN_001747-T1 570 ETLQ 573 6665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (653 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 827 (0.0323742); expected 510.9 (0.02) Passed bias filter: 686 (0.0268546); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6224.10 // Query: FUN_001748-T1 [L=994] Description: FUN_001748 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-05 22.8 0.3 8.5e-05 22.8 0.3 1.8 2 HLH Helix-loop-helix DNA-binding domain Domain annotation for each model (and alignments): >> HLH Helix-loop-helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.3 3.3e-09 8.5e-05 2 52 .. 551 599 .. 550 600 .. 0.94 2 ? -6.6 3.1 1 2.6e+04 8 15 .. 986 993 .. 983 993 .. 0.83 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 3.3e-09 HLH 2 reahnerERrRrdriNdafdeLrellPtlppdkKlsKaeiLrlAieYIkqL 52 +e++ +r R++ +++++af+ Lr+l+P ++ s+ +i +++++YI L FUN_001748-T1 551 KERKKIRDRKYDADLKEAFEHLRSLVP--RVQRSCSRGQIMQETVKYIGLL 599 68999**********************..9999***************877 PP == domain 2 score: -6.6 bits; conditional E-value: 1 HLH 8 rERrRrdr 15 E++R++r FUN_001748-T1 986 DEKKRMRR 993 59***986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (994 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 975 (0.0381679); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 9448.32 // Query: FUN_001749-T1 [L=837] Description: FUN_001749 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-25 88.8 3.3 2.9e-07 30.9 0.2 4.9 5 Ank Ankyrin repeat 1.8e-25 89.8 0.1 2.3e-14 54.2 0.0 2.6 2 Ank_2 Ankyrin repeats (3 copies) 1.7e-16 60.4 0.6 0.00013 22.6 0.1 3.5 3 Ank_4 Ankyrin repeats (many copies) 7.1e-15 54.0 0.4 9.4e-05 23.0 0.1 4.2 4 Ank_3 Ankyrin repeat 1.7e-14 54.2 0.3 0.00013 22.7 0.0 3.6 3 Ank_5 Ankyrin repeats (many copies) 2e-07 31.3 3.9 4.7e-05 23.6 0.2 3.7 3 Ank_KRIT1 KRIT1 ankyrin-repeats domain ------ inclusion threshold ------ 0.088 13.2 0.0 9.3 6.6 0.0 2.5 2 ANK_LRRK2 LRRK2 ANK repeat Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.25 9.1e+02 8 26 .. 18 36 .. 16 41 .. 0.83 2 ! 25.3 0.1 4.8e-09 1.7e-05 2 33 .] 44 75 .. 43 75 .. 0.93 3 ! 27.5 0.1 9.7e-10 3.5e-06 3 32 .. 78 107 .. 77 108 .. 0.88 4 ! 30.9 0.2 7.9e-11 2.9e-07 3 32 .. 111 140 .. 109 141 .. 0.89 5 ? -1.6 0.0 1.7 6.3e+03 2 22 .. 143 163 .. 142 170 .. 0.80 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.25 Ank 8 lAaraghlevvklLLkhGA 26 Aar+g+ e v lL +GA FUN_001749-T1 18 EAARKGQAEEVSLLMASGA 36 69999*********96688 PP == domain 2 score: 25.3 bits; conditional E-value: 4.8e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnardk 33 G +PLHlAa++gh ++++ LL++G++ +ar+k FUN_001749-T1 44 GTSPLHLAAQHGHAQTAEVLLRAGVSRDARTK 75 889******************88***999986 PP == domain 3 score: 27.5 bits; conditional E-value: 9.7e-10 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH+Aa++gh+ v++lL+ +GA+ n d FUN_001749-T1 78 RTPLHMAAQHGHTRVAELLVTSGASTNNAD 107 8*******************55**988655 PP == domain 4 score: 30.9 bits; conditional E-value: 7.9e-11 Ank 3 nTPLHlAaraghlevvklLLkhGAdvnard 32 +TPLH+A++++h++++k+LL++GA +++ FUN_001749-T1 111 MTPLHWACEHNHVDIAKILLQAGARHDIKS 140 7*******99**********88*9888775 PP == domain 5 score: -1.6 bits; conditional E-value: 1.7 Ank 2 GnTPLHlAaraghlevvklLL 22 G T + +A +g++e++ L FUN_001749-T1 143 GKTSIDIARAKGYEEILTVLT 163 78888899989*****99986 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.2 0.0 6.4e-18 2.3e-14 1 89 [. 16 106 .. 16 107 .. 0.88 2 ! 34.1 0.1 1.2e-11 4.2e-08 28 86 .. 109 168 .. 102 171 .. 0.82 Alignments for each domain: == domain 1 score: 54.2 bits; conditional E-value: 6.4e-18 Ank_2 1 LmlAakngnlelvklLl.egadanlqdk.ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadinak 89 L Aa++g+ e v lL+ +ga + ++ g+++LhlAa++gh++++++Ll g++ + ++ rt+Lh Aa++gh +++lL+ +ga+ n FUN_001749-T1 16 LLEAARKGQAEEVSLLMaSGAPFT--TDwLGTSPLHLAAQHGHAQTAEVLLRAGVSRDarTKVDRTPLHMAAQHGHTRVAELLVTSGASTNNA 106 6789*************6666654..446***********************997766767889********************99*999875 PP == domain 2 score: 34.1 bits; conditional E-value: 1.2e-11 Ank_2 28 ngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesghleivklLlekgadi 86 ++t+Lh+A++++h++i+k+Ll+ ga + ++ g+t + +A +g++ei+ +L +g+d FUN_001749-T1 109 LNMTPLHWACEHNHVDIAKILLQAGARHDikSKFGKTSIDIARAKGYEEILTVLT-SGQDQ 168 569********************77554454799*********99*********9.67775 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 2.1e-06 0.0077 2 50 .] 17 64 .. 16 64 .. 0.91 2 ! 17.3 0.0 1.7e-06 0.0063 30 50 .] 77 97 .. 66 97 .. 0.88 3 ! 22.6 0.1 3.7e-08 0.00013 1 49 [. 114 162 .. 114 163 .. 0.95 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 2.1e-06 Ank_4 2 haAaksghlellklLlengadinatdgngetaLhfAasngnlevlklLl 50 Aa +g+ e + lL ++ga+ +td g ++Lh Aa++g+ + ++ Ll FUN_001749-T1 17 LEAARKGQAEEVSLLMASGAP-FTTDWLGTSPLHLAAQHGHAQTAEVLL 64 67999***************5.888767*****************9997 PP == domain 2 score: 17.3 bits; conditional E-value: 1.7e-06 Ank_4 30 getaLhfAasngnlevlklLl 50 ++t+Lh+Aa++g+++v++lL+ FUN_001749-T1 77 DRTPLHMAAQHGHTRVAELLV 97 68*****************96 PP == domain 3 score: 22.6 bits; conditional E-value: 3.7e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAasngnlevlklL 49 lh+A++++h++++k Ll+ ga + ++g t +++A ++g+ e+l L FUN_001749-T1 114 LHWACEHNHVDIAKILLQAGARHDIKSKFGKTSIDIARAKGYEEILTVL 162 8*********************9999******************99877 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 3.5 1.3e+04 6 27 .. 16 36 .. 15 39 .. 0.81 2 ! 10.3 0.0 0.00037 1.3 4 28 .. 46 69 .. 43 72 .. 0.88 3 ! 15.6 0.0 6.5e-06 0.024 3 28 .. 78 102 .. 76 105 .. 0.89 4 ! 23.0 0.1 2.6e-08 9.4e-05 2 27 .. 110 134 .. 109 135 .. 0.91 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 3.5 Ank_3 6 LhlAarngrleivklLleklga 27 L Aar g+ e v lL ga FUN_001749-T1 16 LLEAARKGQAEEVSLLMA-SGA 36 6779****9998999988.666 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00037 Ank_3 4 tpLhlAarngrleivklLleklgad 28 +pLhlAa +g+ + +++Ll+ g++ FUN_001749-T1 46 SPLHLAAQHGHAQTAEVLLR-AGVS 69 8***********99*****9.7775 PP == domain 3 score: 15.6 bits; conditional E-value: 6.5e-06 Ank_3 3 ntpLhlAarngrleivklLleklgad 28 +tpLh+Aa +g+ +++lL+ ga+ FUN_001749-T1 78 RTPLHMAAQHGHTRVAELLVT-SGAS 102 8******************99.7776 PP == domain 4 score: 23.0 bits; conditional E-value: 2.6e-08 Ank_3 2 gntpLhlAarngrleivklLleklga 27 ++tpLh+A+++++++i+k Ll+ ga FUN_001749-T1 110 NMTPLHWACEHNHVDIAKILLQ-AGA 134 68*******************9.665 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.0 1.9e-05 0.07 15 46 .. 43 74 .. 31 75 .. 0.83 2 ! 14.2 0.1 1.7e-05 0.063 18 44 .. 79 105 .. 75 108 .. 0.85 3 ! 22.7 0.0 3.7e-08 0.00013 10 56 .] 104 150 .. 100 150 .. 0.90 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.9e-05 Ank_5 15 egytpLhvAakygaleivrlLlangvdlnlkd 46 g+ pLh+Aa +g+++ +++Ll gv+ +++ FUN_001749-T1 43 LGTSPLHLAAQHGHAQTAEVLLRAGVSRDART 74 5789******************8888877765 PP == domain 2 score: 14.2 bits; conditional E-value: 1.7e-05 Ank_5 18 tpLhvAakygaleivrlLlangvdlnl 44 tpLh+Aa +g+ ++++lL+ g++ n+ FUN_001749-T1 79 TPLHMAAQHGHTRVAELLVTSGASTNN 105 9*****************977777665 PP == domain 3 score: 22.7 bits; conditional E-value: 3.7e-08 Ank_5 10 nrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 n d +tpLh A+++++ +i+++Ll g+ +k ++g+t +d+A FUN_001749-T1 104 NNADMLNMTPLHWACEHNHVDIAKILLQAGARHDIKSKFGKTSIDIA 150 55555678**************************************9 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.3 0.1 0.00068 2.5 20 69 .. 14 67 .. 4 77 .. 0.82 2 ! 23.6 0.2 1.3e-08 4.7e-05 20 128 .. 46 153 .. 42 160 .. 0.81 3 ? 2.4 0.1 0.044 1.6e+02 88 119 .. 622 653 .. 597 658 .. 0.77 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.00068 Ank_KRIT1 20 eeLrkaaakGdeetvariLnvrekvddpes.....lvaAakgGheevlqlLlalG 69 ++L +aa kG++e v ++ + ++ l+ Aa+ Gh + ++Ll G FUN_001749-T1 14 KRLLEAARKGQAEEVSLLMASGAPF-TTDWlgtspLHLAAQHGHAQTAEVLLRAG 67 678999*********9999988877.333233445*****************988 PP == domain 2 score: 23.6 bits; conditional E-value: 1.3e-08 Ank_KRIT1 20 eeLrkaaakGdeetvariLnvrekvd.....dpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeef 110 + L+ aa++G ++t++ +L+ + d d l++Aa+ Gh++v +lL+ G + + + tPl a ++++++ k+ll+ FUN_001749-T1 46 SPLHLAAQHGHAQTAEVLLRAGVSRDartkvDRTPLHMAAQHGHTRVAELLVTSGASTNNADML------NMTPLHWACEHNHVDIAKILLQAGAR 135 6799999*****99999998654443111115566********************988884444......459******************99988 PP Ank_KRIT1 111 dptrrlkgetyleiarer 128 + g+t ++iar + FUN_001749-T1 136 HDIKSKFGKTSIDIARAK 153 88888999******9976 PP == domain 3 score: 2.4 bits; conditional E-value: 0.044 Ank_KRIT1 88 PllAaiGrenlkvikllldqeefdptrrlkge 119 a G + +v++l l+q++++ + +++ FUN_001749-T1 622 EQASASGTSQSSVVQLQLQQDQLNLAQLMQNA 653 44579999**************9988776665 PP >> ANK_LRRK2 LRRK2 ANK repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.024 87 36 89 .. 49 102 .. 39 108 .. 0.77 2 ? 6.6 0.0 0.0025 9.3 32 66 .. 111 147 .. 103 186 .. 0.76 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.024 ANK_LRRK2 36 ekaCeegdvvmaEcllllgadvnkktktesliyqvCErgsplelvelllssgvr 89 + a ++g++ aE ll+ g + +tk + ++ + ++++++ell++sg+ FUN_001749-T1 49 HLAAQHGHAQTAEVLLRAGVSRDARTKVDRTPLHMAAQHGHTRVAELLVTSGAS 102 567777888888888888888888888887777778888888888888888875 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0025 ANK_LRRK2 32 eklLekaCeegdvvmaEcllllga..dvnkktktesl 66 + L+ aCe+++v +a ll+ ga d+ k ++s+ FUN_001749-T1 111 MTPLHWACEHNHVDIAKILLQAGArhDIKSKFGKTSI 147 455889*****************95555555555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (837 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3444 (0.134821); expected 510.9 (0.02) Passed bias filter: 661 (0.0258759); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.49u 0.39s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 7927.89 // Query: FUN_001749-T2 [L=473] Description: FUN_001749 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (473 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3727 (0.145899); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.46u 0.36s 00:00:00.82 Elapsed: 00:00:00.42 # Mc/sec: 4525.34 // Query: FUN_001749-T3 [L=637] Description: FUN_001749 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (637 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3603 (0.141045); expected 510.9 (0.02) Passed bias filter: 626 (0.0245058); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.48u 0.38s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 6131.86 // Query: FUN_001750-T1 [L=369] Description: FUN_001750 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-21 76.5 0.0 3.4e-21 76.2 0.0 1.1 1 Epimerase NAD dependent epimerase/dehydratase family 4.4e-09 36.3 0.0 7e-09 35.7 0.0 1.4 1 RmlD_sub_bind RmlD substrate binding domain 8.6e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 GDP_Man_Dehyd GDP-mannose 4,6 dehydratase 2.6e-07 31.2 0.0 5.2e-07 30.2 0.0 1.5 1 NAD_binding_10 NAD(P)H-binding 3.9e-07 29.9 0.0 8.1e-07 28.8 0.0 1.5 1 3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomeras ------ inclusion threshold ------ 0.024 14.3 0.0 0.051 13.2 0.0 1.5 2 Polysacc_synt_2 Polysaccharide biosynthesis protein 0.13 13.1 0.0 0.23 12.3 0.0 1.5 1 Sacchrp_dh_NADP Saccharopine dehydrogenase NADP binding doma Domain annotation for each model (and alignments): >> Epimerase NAD dependent epimerase/dehydratase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.2 0.0 9.4e-25 3.4e-21 1 240 [] 7 244 .. 7 244 .. 0.87 Alignments for each domain: == domain 1 score: 76.2 bits; conditional E-value: 9.4e-25 Epimerase 1 ilVtGatGfiGsalveallekg..yevigldrrssasntarladl........elveldltdkdalekllkev..kpdavihlAavsgvaasledp 84 +l++G+ Gf+G++lv +l e+ ++ +d+ + + ++ ++++ e+ ++l ++ ++ek++ + ++d+ i++Aa+ +++s + FUN_001750-T1 7 VLILGGLGFVGRNLVCYLVEHElcSKIRSVDKVPPSTAWLNERHNaafhhdsvEFKSANLINPVSVEKAFLDSdgGFDVCINCAAETRYGQSEKVY 102 79********************9888*******9999999999889**********************99888789***************99999 PP Epimerase 85 edtieanvlgtlnlleaarkagvkrfvfasssevYGkgaeipqeettetgplapnspYaaaKlaaerlveayaaeyglravilrlfnvyGpgrgeg 180 ed i+ +++ln ++ a k +vkr++ +s+++vY ++ +e+++t+p+ + Y Kl +e+ + ++ gl++vi+r+ +yG + +g FUN_001750-T1 103 EDGIY---KLSLNCAKQAIKFKVKRYIEISTAQVYSCNKGE-SDEKSKTSPWTQIAKY---KLLVEEELAKL---DGLNYVIVRPAIMYGIADRQG 188 99887...9***************************88884.8888866666665555...69999888765...89***************5555 PP Epimerase 181 f.vsrvipalirrilegkeilllgdgtqrRdflyvdDvaeaillalekpdagekgeiyniG 240 ++ +i a+ +++ e+ +ll + + ++ ++v+D+++a++++ ++ g +g+++n++ FUN_001750-T1 189 LtPRLIIGAVYKQMGEKM--KLLWTKDLKMCTVHVNDACRALWHLSNH---GNSGDVFNLA 244 548888888888886654..44445778889*****************...889999*986 PP >> RmlD_sub_bind RmlD substrate binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.7 0.0 1.9e-12 7e-09 2 201 .. 6 236 .. 5 295 .. 0.75 Alignments for each domain: == domain 1 score: 35.7 bits; conditional E-value: 1.9e-12 RmlD_sub_bind 2 kilitGanGqlGteLakalaeegievvaltre...........................eldltdaeavaellkeik..pdvvvnaAaytavDkaE 68 ++li+G+ G +G++L+ l e++ + + r+ +++l ++ +v++++ + + dv +n+Aa t+ + E FUN_001750-T1 6 RVLILGGLGFVGRNLVCYLVEHE--LCSKIRSvdkvppstawlnerhnaafhhdsvefkSANLINPVSVEKAFLDSDggFDVCINCAAETRYGQSE 99 699************99999776..44443444567999999**************999*************966542289*************** PP RmlD_sub_bind 69 se.eeaaykvnaeavenlAeaaaavga.lLvyvStdyVFdGekkepYeeddetsPlnvYGrtklaGEqavra.alkkalivRtswvyge......k 155 + e+ yk+ + n A++a + ++ + +St V+ +k e e+++tsP + ++ kl+ E+ + + ++ +++ivR + +yg + FUN_001750-T1 100 KVyEDGIYKL----SLNCAKQAIKFKVkRYIEISTAQVYSCNKGE-SDEKSKTSPWTQIAKYKLLVEEELAKlDGLNYVIVRPAIMYGIadrqglT 190 9945555555....4566777777776258************776.79******************999988799************984333333 PP RmlD_sub_bind 156 gknfvktmlrlakereelkvvdDqvgsPTsardlAevllellekka 201 + + + + + e+ +l +D + +++d ++l +l ++ + FUN_001750-T1 191 PRLIIGAVYKQMGEKMKLLWTKDLKMCTVHVNDACRALWHLSNHGN 236 3344445555555555555566666666666666666666555555 PP >> GDP_Man_Dehyd GDP-mannose 4,6 dehydratase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.0 0.0 3.3e-11 1.2e-07 1 264 [. 8 260 .. 8 295 .. 0.77 Alignments for each domain: == domain 1 score: 32.0 bits; conditional E-value: 3.3e-11 GDP_Man_Dehyd 1 LiTGitGqiGsylaelLlekgyevhgivrrsssfntgrlehlkkdpkeeleenlklhkgDltDseslerllkevk..pdevynLAAqshVdvsfek 94 Li G+ G++G +l+ +L+e + + ++ +t+ l++ + + + ++++++ +++l + s+e+++ + + +d ++n AA+ ++s FUN_001750-T1 8 LILGGLGFVGRNLVCYLVEHELCSKIRSVDKVPPSTAWLNERH-NAAFH-HDSVEFKSANLINPVSVEKAFLDSDggFDVCINCAAETRYGQS--- 98 89*****************975444333344444566776654.44455.689******************8884449********9877666... PP GDP_Man_Dehyd 95 PeytaetnvlGtlrL.LeairelglekkvrfyqaStsEvYGkvqevpqtEttpfyPrsPYaaaKlyaewivvnyresyglfavngilfnhesprrg 189 e+++e G ++L L++++++ + k +r++ +St+ vY + ++ + +E+ ++ P + a Kl e+ + + gl v+ + ++ FUN_001750-T1 99 -EKVYED---GIYKLsLNCAKQAIKFKVKRYIEISTAQVY-SCNKGESDEKSKTSPWTQIAKYKLLVEE---ELAKLDGLNYVIVRPAIMYGIADR 186 .555665...8888889999999888999***********.5667889999999999988888887775...667789999999999999**9998 PP GDP_Man_Dehyd 190 eefvtrkitravarikagkqeklvlGnldakRdwgyakDyveamwlmlqqdepdd.yviatgethsvrefvekafa 264 + r+i+ av + +k + l d k +++D ++a+w + +++++ d +++a++ ++ +++ + ++ FUN_001750-T1 187 QGLTPRLIIGAVYKQMGEKMKLL--WTKDLKMCTVHVNDACRALWHLSNHGNSGDvFNLADKSNTTQGSITNFVCE 260 99999999999988555555544..566667899****************99877366777666666655555544 PP >> NAD_binding_10 NAD(P)H-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 0.0 1.4e-10 5.2e-07 3 146 .. 13 180 .. 11 191 .. 0.69 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 1.4e-10 NAD_binding_10 3 tGkiGrllvkqllargghevtalvRnpekla............dleaeaglevvegdvtdaedlaealkgad....aVisalggggt...deeg. 77 G +Gr lv l+++ e+ +R+ +k++ ++ +++ +e +++ ++ ++++a+ + d + i ++ ++ + e FUN_001750-T1 13 LGFVGRNLVCYLVEH---ELCSKIRSVDKVPpstawlnerhnaAF-HHDSVEFKSANLINPVSVEKAFLDSDggfdVCINCA-AETRygqS-EKv 101 566666666666643...344444444444444444444433256.48999999**************86664331544444.33333542.223 PP NAD_binding_10 78 ........akniidaakeagvkrfilvsalgvgdevpgkfgewnk.evlkaylaakraaeellra.sgldytivrpgaL 146 n+++ a + +vkr+i +s+++v+ +g+ +e k + + ++++ k ee l + gl+y+ivrp+ + FUN_001750-T1 102 yedgiyklSLNCAKQAIKFKVKRYIEISTAQVYSCNKGESDEKSKtSPWTQIAKYKLLVEEELAKlDGLNYVIVRPAIM 180 55557777999999999****************9777776655442688999999999999998878*********975 PP >> 3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 0.0 2.2e-10 8.1e-07 1 188 [. 8 187 .. 8 221 .. 0.69 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 2.2e-10 3Beta_HSD 1 vvtGggGFlGralikeLvkleelkevrvlD.....vrespelleelskvnvkk....viegDvtdkdkleealegvd....vvihtaalvdvagkl 83 +++Gg GF+Gr+l+ Lv+ e ++r++D +l+e ++ ++ + + + + ++e+a ++d v i ++ + + + FUN_001750-T1 8 LILGGLGFVGRNLVCYLVEHELCSKIRSVDkvppsT----AWLNERHNAAFHHdsveFKSANLINPVSVEKAFLDSDggfdVCIN--CAAETRYGQ 97 699***************************643333....55555544444333455999************9877622114444..444444445 PP 3Beta_HSD 84 tedeimkvnvkGTrnvleacvkagvrvlvYtSsaevvgpnslgeeilngdEeteyesthkdaypesKalaEklvlkaNgrtlknggrlyTcaLRpa 179 +e+ + + ++k n + ++k v++ + S+a+v n+ + +++ ++++ ++ K l E+ + k g l+ + +Rpa FUN_001750-T1 98 SEKVYEDGIYKLSLNCAKQAIKFKVKRYIEISTAQVYSCNKG-------ESDEKSKTSPWTQIAKYKLLVEEELAKLDG--------LNYVIVRPA 178 555566666666666777777888999999999999887543.......333334444555566777777777666666........666777777 PP 3Beta_HSD 180 giyGegdkl 188 ++yG d++ FUN_001750-T1 179 IMYGIADRQ 187 777766655 PP >> Polysacc_synt_2 Polysaccharide biosynthesis protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 1.4e-05 0.051 1 129 [. 7 131 .. 7 139 .. 0.92 2 ? -3.1 0.0 1.4 5e+03 204 228 .. 219 243 .. 211 265 .. 0.75 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1.4e-05 Polysacc_synt_2 1 vlvtGagGsiGselvrqilke.kpkkiilfsrdElklyeiekeleeelkekklkfeivpvigdvrdkerlekaleelkvdvvfhaAAlKhvPlv 93 vl+ G+ G +G++lv +++ ++ki+ +++ + +++++++ +++++++f+ + +i v ++ + + dv++++AA + FUN_001750-T1 7 VLILGGLGFVGRNLVCYLVEHeLCSKIRSVDKVPPSTAWLNERHNAAFHHDSVEFKSANLINPVSVEKAFLDSDG--GFDVCINCAAETRYGQS 98 89***************99996789*******************9***********9999999998888877666..9**************** PP Polysacc_synt_2 94 eenpleaiktNvlGtenvieaaieagvkkvvliStD 129 e+ ++i + n+++ ai+ +vk+ + iSt FUN_001750-T1 99 EKVYEDGIYK---LSLNCAKQAIKFKVKRYIEISTA 131 **99999986...4789*****************96 PP == domain 2 score: -3.1 bits; conditional E-value: 1.4 Polysacc_synt_2 204 mtieeavqLvlqalalakggeifvl 228 + +++a++ + + +++++g++f l FUN_001750-T1 219 VHVNDACRALWHLSNHGNSGDVFNL 243 5677888888888888888888854 PP >> Sacchrp_dh_NADP Saccharopine dehydrogenase NADP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 6.4e-05 0.23 1 79 [. 7 93 .. 7 103 .. 0.84 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 6.4e-05 Sacchrp_dh_NADP 1 vliiGa.GsvGqgvapllarhgdvdeitvadrtkekaqalaakl....rgvrfkaaavdadnyeavLeallkeg...dlvvnlappv 79 vli+G+ G+vG+ ++ +l++h+ ++i +d+ + + l + ++ ++++++ + n +v +a l d+++n+a + FUN_001750-T1 7 VLILGGlGFVGRNLVCYLVEHELCSKIRSVDKVPPSTAWLNERHnaafHHDSVEFKSANLINPVSVEKAFLDSDggfDVCINCAAET 93 89*******************9999*******9999776666557788999999999999999996666676657899****99766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (369 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 680 (0.0266197); expected 510.9 (0.02) Passed bias filter: 581 (0.0227442); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3627.41 // Query: FUN_001755-T1 [L=1171] Description: FUN_001755 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-28 99.6 3.8 5.9e-28 98.5 3.8 1.5 1 Lyase_8 Polysaccharide lyase family 8, super-sandwich 5.1e-28 98.8 0.1 8.8e-28 98.0 0.1 1.3 1 Lyase_catalyt Lyase, catalytic 1.1e-14 55.1 1.2 1.8e-14 54.5 0.1 1.9 2 Lyase_N Lyase, N terminal Domain annotation for each model (and alignments): >> Lyase_8 Polysaccharide lyase family 8, super-sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.5 3.8 7e-32 5.9e-28 11 250 .. 720 984 .. 714 988 .. 0.83 Alignments for each domain: == domain 1 score: 98.5 bits; conditional E-value: 7e-32 Lyase_8 11 vhrrpgyvfslkmfSsRtanyE.cgngenlrgwhtgdGmtylylsg..deYediwptvdwnrlPGtTvdtketalsasktkae.gaakgksdfvGG 102 vhrr+++v++ k f + + +E n+en +g + + G++ + +s+ +d+ +dw ++PGtT+ + a+ g+ gk+ +GG FUN_001755-T1 720 VHRRKDWVATAKGFNKYVWDFEnKPNKENIYGLYASHGALLIANSEalLSVHDVEKGWDWTKVPGTTSIALDLADMNM----GgGRFFGKRYLAGG 811 9*********************889*********************776777*****************999998643....3377778******* PP Lyase_8 103 vs.dgey....Gaagmdltnpet..........stltakKsWfflddeivalgagikasdgea..veTtvdqrklngevvvsentatl........ 173 + +g+y G+ gmd+++p+ + ++kKs+ff+++ iv lg+ i+a+++++ v Tt+ q kl + v s+ ++ FUN_001755-T1 812 LTfKGTYplgnGVFGMDFDQPSYglattdwrndIEFKFKKSFFFFQNLIVGLGSHISAQNTNSkiVQTTLFQDKLFDGVSSSKI--KVngvdktfs 905 *****977777**********99999****9884499*************************99***********665533222..2222344457 PP Lyase_8 174 .ssqgssetaaevkW....ghdnvGYvfpeksa.klsvsreertGswsdInssskkevtkdvftlwldhgkkpsnasyaYlvl 250 + + + ++++v++ ++ Y++p++s+ +l+v+ ++++ + + k+++t +++t+w+dh+++p+n +y+Y+vl FUN_001755-T1 906 dTVNAYTPNIQNVAYttltDAKGNFYYIPSNSKtSLKVHLKDQNSKTD----DGKTDTTGRYATAWFDHSTSPNNGKYEYAVL 984 777777888888888999855666677777632255555555554443....467999**********************997 PP >> Lyase_catalyt Lyase, catalytic # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.0 0.1 1e-31 8.8e-28 122 331 .. 406 631 .. 388 662 .. 0.81 Alignments for each domain: == domain 1 score: 98.0 bits; conditional E-value: 1e-31 Lyase_catalyt 122 amldhltDqGvayGsglgtiHHyGYslrkly.vsalLmkdvlrkegk...leeaertlrwyaalnevyrkPlpessD..lDsfntllsgklasill 211 ++ld+++DqG+a+Gsglg++ H + + s lL+ d l+++ + l + +t +wy +evy+ P e + D t l+ +++ +l+ FUN_001755-T1 406 HLLDYVKDQGFADGSGLGSLDHEMNRVGAGFsHSLLLLSDSLNEASNksrLLDLIETAKWYNDFGEVYQSPAFEYKGttADRMITILHFRVMIVLV 501 579*****************999998876662688999****9976511155667899*************976544449**************** PP Lyase_catalyt 212 medspek.....lqyLkslsrwldvglrpakgllgslkvDGaafhHennYP.aYavgglkgitqliyllsgtsfalseearetvkkalLamrfYcn 301 m+ s ++ ++ + + rw++ + + + g +k+D + fhH+ Y aY +l+ ++ + yll+gt+f lse + ++++ l +r + FUN_001755-T1 502 MPKSTDQekkarIRDMDAIVRWMNNAFAVNDAFGGVIKPDYTGFHHQAIYGsAYVPQALQVAGLVKYLLHGTKFSLSETSVNNIRRGLEVIRLMAA 597 99876541111144567789******************************63899999************************************** PP Lyase_catalyt 302 klewplslsGRHPdgskkltdl....ayallAla 331 k++ p s+ GR P+ s+k+ ya++ +a FUN_001755-T1 598 KYSSPNSINGRFPNYSNKVLIKaalgGYAYFSVA 631 **************99887554355667777765 PP >> Lyase_N Lyase, N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.5 0.1 2.1e-18 1.8e-14 2 165 .. 32 200 .. 31 201 .. 0.76 2 ? -3.3 0.1 1.3 1.1e+04 36 69 .. 216 253 .. 214 256 .. 0.75 Alignments for each domain: == domain 1 score: 54.5 bits; conditional E-value: 2.1e-18 Lyase_N 2 ervisFeekqlpefvk....asskselslssahykdGkqsLeWefqpqstlslkkelkleakdk.tekdlglkafklWvynEkp.qddsivfefld 91 ++v++Fe + ++++ s + +ls s++ k G++sL+W+ + s sl+ + + + ++ t+ l + +k+W+y + + ++++ ef d FUN_001755-T1 32 DQVFDFETSAEANCFQlvpvGSGTKTLSSSKKTVKFGQKSLKWHATSTSPSSLQLD--FATGHHiTSSWLRRGGVKVWLYKNSAsPGKQLKAEFKD 125 799****99888777653334667789999**************999999999888..776665055555666789****665516799******* PP Lyase_N 92 kdGkvsasfkfklnfkGWRavwvsyer....dlegkkekdidelrvvaPevkgrlfiDrlilaekvdarqqtpDaqvp 165 + +v + f+ +lnfkGWR++wv +++ ++++ i+ + ++ ++iD l +++ +qt D+ vp FUN_001755-T1 126 TSDNVLCLFNANLNFKGWRGIWVKFSEckpsGISVTSSSTINRVLFTL-TGADTIYIDILEFKNSLG--KQTRDKIVP 200 *************************99643333444555555554433.445789***999998855..788888776 PP == domain 2 score: -3.3 bits; conditional E-value: 1.3 Lyase_N 36 qsLeWefqpq....stlslkkelkleakdktekdlglk 69 +s +W+ qp+ st+++ k+l+l+ ++ +++l FUN_001755-T1 216 RSYHWSQQPApdlpSTVDVTKNLNLDVIKSRMMNWYLD 253 68888888865555889999999998888888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1171 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 875 (0.0342533); expected 510.9 (0.02) Passed bias filter: 607 (0.023762); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.44u 0.39s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 11298.30 // Query: FUN_001756-T1 [L=61] Description: FUN_001756 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (61 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 688 (0.0269329); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 607.99 // Query: FUN_001757-T1 [L=94] Description: FUN_001757 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (94 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 318 (0.0124486); expected 510.9 (0.02) Passed bias filter: 299 (0.0117048); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 951.36 // Query: FUN_001759-T1 [L=138] Description: FUN_001759 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-11 43.5 19.8 5.7e-11 43.2 19.8 1.1 1 STPRs STPRs (score and three amino acid peptide repeats ------ inclusion threshold ------ 0.1 11.8 0.0 0.12 11.6 0.0 1.2 1 ATG22 Vacuole effluxer Atg22 like Domain annotation for each model (and alignments): >> STPRs STPRs (score and three amino acid peptide repeats) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.2 19.8 4.5e-15 5.7e-11 1 74 [] 57 130 .. 57 130 .. 0.98 Alignments for each domain: == domain 1 score: 43.2 bits; conditional E-value: 4.5e-15 STPRs 1 eRakRLakmkaraklRrAnEsPeqRakRLkklaeyarkrrasEtrdqRalRLaemaayAkrRlAnEtPeqRkeR 74 e+ kRL + k Rr nEs e + kRL++ + +k+ra E+ + R++RLa + y ++++AnE+ e R+eR FUN_001759-T1 57 EKEKRLIVRREYEKRRRVNESEESKEKRLAQQCLKRKKKRANESSESRKKRLATQSQYQRQKIANESAEFREER 130 6789*********************************************************************9 PP >> ATG22 Vacuole effluxer Atg22 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 9.1e-06 0.12 144 173 .. 3 92 .. 1 126 [. 0.71 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 9.1e-06 ATG22 144 slvllnsflPllvrndpelrkaeeeleee.................................................................e 173 ++v++n+++Pll+r+ ++ ee+ + + FUN_001759-T1 3 MIVFYNAYIPLLIRQANDV---EENP--GptifdvidptrticadyiqgnvalfgenaeekekrlivrreyekrrrvneseeskekrlaqqclkR 92 68**************999...3333..2346779999999999999999999999888888888888888776666655555555555555541 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (138 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2779 (0.108788); expected 510.9 (0.02) Passed bias filter: 715 (0.0279898); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1366.87 // Query: FUN_001762-T1 [L=1219] Description: FUN_001762 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-28 99.5 4.0 6.4e-28 98.4 4.0 1.5 1 Lyase_8 Polysaccharide lyase family 8, super-sandwich 5.5e-28 98.7 0.1 9.6e-28 97.9 0.1 1.3 1 Lyase_catalyt Lyase, catalytic 1.1e-14 55.2 1.1 1.7e-14 54.6 0.1 1.9 2 Lyase_N Lyase, N terminal ------ inclusion threshold ------ 0.28 11.5 0.7 32 4.9 0.1 2.6 2 DUF7226 Domain of unknown function (DUF7226) Domain annotation for each model (and alignments): >> Lyase_8 Polysaccharide lyase family 8, super-sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.4 4.0 1e-31 6.4e-28 11 250 .. 768 1032 .. 762 1037 .. 0.83 Alignments for each domain: == domain 1 score: 98.4 bits; conditional E-value: 1e-31 Lyase_8 11 vhrrpgyvfslkmfSsRtanyE.cgngenlrgwhtgdGmtylylsg..deYediwptvdwnrlPGtTvdtketalsasktkae.gaakgksdfv 100 vhrr+++v++ k f + + +E n+en +g + + G++ + +s+ +d+ +dw ++PGtT+ + a+ g+ gk+ + FUN_001762-T1 768 VHRRKDWVATAKGFNKYVWDFEnKPNKENIYGLYASHGALLIANSEalLSVHDVEKGWDWTKVPGTTSIALDLADMNM----GgGRFFGKRYLA 857 9*********************889*********************776777*****************999998643....3377778***** PP Lyase_8 101 GGvs.dgey....Gaagmdltnpet..........stltakKsWfflddeivalgagikasdgea..veTtvdqrklngevvvsentatl.... 173 GG + +g+y G+ gmd+++p+ + ++kKs+ff+++ iv lg+ i+a+++++ v Tt+ q kl + v s+ ++ FUN_001762-T1 858 GGLTfKGTYplgnGVFGMDFDQPSYglattdwrndIEFKFKKSFFFFQNLIVGLGSHISAQNTNSkiVQTTLFQDKLFDGVSSSKI--KVngvd 949 *******977777**********99999****9884499*************************99***********665533222..222234 PP Lyase_8 174 .....ssqgssetaaevkW....ghdnvGYvfpeksa.klsvsreertGswsdInssskkevtkdvftlwldhgkkpsnasyaYlvl 250 + + + ++++v++ ++ Y++p++s+ +l+v+ ++++ + + k+++t +++t+w+dh+++p+n +y+Y+vl FUN_001762-T1 950 ktfsdTVNAYTPNIQNVAYttltDAKGNFYYIPSNSKtSLKVHLKDQNSKTD----DGKTDTTGRYATAWFDHSTSPNNGKYEYAVL 1032 4457777777888888888999855666677777632255555555554443....467999**********************986 PP >> Lyase_catalyt Lyase, catalytic # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 97.9 0.1 1.5e-31 9.6e-28 122 331 .. 454 679 .. 436 710 .. 0.81 Alignments for each domain: == domain 1 score: 97.9 bits; conditional E-value: 1.5e-31 Lyase_catalyt 122 amldhltDqGvayGsglgtiHHyGYslrkly.vsalLmkdvlrkegk...leeaertlrwyaalnevyrkPlpessD..lDsfntllsgklasill 211 ++ld+++DqG+a+Gsglg++ H + + s lL+ d l+++ + l + +t +wy +evy+ P e + D t l+ +++ +l+ FUN_001762-T1 454 HLLDYVKDQGFADGSGLGSLDHEMNRVGAGFsHSLLLLSDSLNEASNksrLLDLIETAKWYNDFGEVYQSPAFEYKGttADRMITILHFRVMIVLV 549 579*****************999998876662688999****9976511155667899*************976544449**************** PP Lyase_catalyt 212 medspek.....lqyLkslsrwldvglrpakgllgslkvDGaafhHennYP.aYavgglkgitqliyllsgtsfalseearetvkkalLamrfYcn 301 m+ s ++ ++ + + rw++ + + + g +k+D + fhH+ Y aY +l+ ++ + yll+gt+f lse + ++++ l +r + FUN_001762-T1 550 MPKSTDQekkarIRDMDAIVRWMNNAFAVNDAFGGVIKPDYTGFHHKAIYGsAYVPQALQVAGLVKYLLHGTKFSLSETSVNNIRRGLEVIRLMAA 645 99876541111144567789******************************63899999************************************** PP Lyase_catalyt 302 klewplslsGRHPdgskkltdl....ayallAla 331 k++ p s+ GR P+ s+k+ ya++ +a FUN_001762-T1 646 KYSSPNSINGRFPNYSNKVLIKaalgGYAYFSVA 679 **************99887554355667777765 PP >> Lyase_N Lyase, N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.6 0.1 2.6e-18 1.7e-14 2 165 .. 80 248 .. 79 249 .. 0.76 2 ? -3.4 0.1 1.8 1.1e+04 36 69 .. 264 301 .. 262 304 .. 0.75 Alignments for each domain: == domain 1 score: 54.6 bits; conditional E-value: 2.6e-18 Lyase_N 2 ervisFeekqlpefvk....asskselslssahykdGkqsLeWefqpqstlslkkelkleakdk.tekdlglkafklWvynEkp.qddsivfefld 91 ++v++Fe + ++++ s + +ls s++ k G++sL+W+ + s +l+ + + + ++ t+ l + +k+W+y + + ++++ ef d FUN_001762-T1 80 DQVFDFETSAEANCFQlvpvGSGTKTLSSSKKTVKFGQKSLKWHATSTSPSTLQLD--FATGHHiTSSWLRRGGVKVWLYKNSAsPGKQLKAEFKD 173 799****99888777653334667789999*************9998888888877..666555055555666789****665516799******* PP Lyase_N 92 kdGkvsasfkfklnfkGWRavwvsyer....dlegkkekdidelrvvaPevkgrlfiDrlilaekvdarqqtpDaqvp 165 + +v + f+ +lnfkGWR++wv +++ ++++ i+ + ++ ++iD l +++ +qt D+ vp FUN_001762-T1 174 TSDNVLCLFNANLNFKGWRGIWVKFSEckpsGISVTSSSTINRVLFTL-TGADTIYIDILEFKNSLG--KQTRDKIVP 248 *************************99643333444555555554433.445789***999998855..788888776 PP == domain 2 score: -3.4 bits; conditional E-value: 1.8 Lyase_N 36 qsLeWefqpq....stlslkkelkleakdktekdlglk 69 +s +W+ qp+ st+++ k+l+l+ ++ +++l FUN_001762-T1 264 RSYHWSQQPApdlpSTVDVTKNLNLDVIKSRMMNWYLD 301 68888888865555889999999998888888888876 PP >> DUF7226 Domain of unknown function (DUF7226) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.005 32 49 117 .. 380 449 .. 371 455 .. 0.81 2 ? 4.2 0.1 0.008 51 19 52 .. 713 746 .. 701 757 .. 0.79 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.005 DUF7226 49 eekevkvsLteeGkkilklkykerqlklvklilehevFkkvlkeylke.geipekeeiveimkesnlynv 117 +++e+ + t+e ++ + e++ ++ + +h++ ++v++++l + ++ +k+++ + +k+ n ++ FUN_001762-T1 380 RTNEIDSTATDELANLNSAVAAEKNSAYQAIAGQHQAMQDVFRTFLPSsSNPLTKNQVKNAIKALNCNRL 449 567777788888888889999999999999999************96615666999******99998765 PP == domain 2 score: 4.2 bits; conditional E-value: 0.008 DUF7226 19 itenydfdeRQtdYYtnAgrYLgLvekkkeeeke 52 it d + R +YY n+ L+L++k ++++ + FUN_001762-T1 713 ITILRDGSIRKNKYYLNSLGALDLMKKVQTTSTS 746 5555566789*****************9875544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 914 (0.03578); expected 510.9 (0.02) Passed bias filter: 650 (0.0254453); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.40u 0.46s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 11663.34 // Query: FUN_001763-T1 [L=1184] Description: FUN_001763 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-29 103.8 2.3 1.4e-29 103.8 2.3 1.6 2 Lyase_8 Polysaccharide lyase family 8, super-sandwich 1.2e-27 97.6 0.1 2.2e-27 96.7 0.1 1.4 1 Lyase_catalyt Lyase, catalytic 1.1e-15 58.4 1.4 1.5e-15 58.0 0.1 1.9 2 Lyase_N Lyase, N terminal ------ inclusion threshold ------ 0.045 14.1 0.2 0.36 11.2 0.0 2.6 3 CobW_C_DAAF9 DAAF9 CobW_C-like domain Domain annotation for each model (and alignments): >> Lyase_8 Polysaccharide lyase family 8, super-sandwich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 103.8 2.3 2.2e-33 1.4e-29 11 250 .. 733 997 .. 727 1002 .. 0.81 2 ? -3.3 0.0 1.1 7.1e+03 121 140 .. 1035 1054 .. 1015 1060 .. 0.73 Alignments for each domain: == domain 1 score: 103.8 bits; conditional E-value: 2.2e-33 Lyase_8 11 vhrrpgyvfslkmfSsRtanyE.cgngenlrgwhtgdGmtylylsg..deYediwptvdwnrlPGtTvdtketalsasktkaegaakgksdfvGGv 103 vhrr+++v++ k f + + +E n+en +g + + G++ + +s+ +d+ +dw ++PGtT+ + a+ + + gk+d +GG FUN_001763-T1 733 VHRRKDWVATAKGFNKYVWDFEnQPNKENIYGLYASHGALLIANSEalLSVHDVDKGWDWTKVPGTTSIALDLADMDMG--G-ARFFGKKDLAGGL 825 9*********************889*********************776777*****************9999986433..2.33456******** PP Lyase_8 104 s.dgey....Gaagmdltnpet..........stltakKsWfflddeivalgagikasdgea..veTtvdqrklngevvvsentatl......... 173 + +g+y G+ gmd+++p+ + ++kKs+ff+++ iv lg+ i+a+d++ v Tt+ q +l + v s+ ++ FUN_001763-T1 826 TfKGTYllgnGIFGMDFDQPSYglattdprndIEFKFKKSFFFFQNLIVGLGSHISAQDTNGkiVQTTLFQDRLFDGVSSSKI--KVngvdktfsn 919 ****977777**********99999****9884499************************99999999999999655522222..22223444577 PP Lyase_8 174 ssqgssetaaevkW....ghdnvGYvfpeksa.klsvsreertGswsdInssskkevtkdvftlwldhgkkpsnasyaYlvl 250 + + + ++++v++ ++ Y++p++s+ +l+v+ ++++ + + k+++t +++t+w+dh+++psn++y+Y+vl FUN_001763-T1 920 TANAYNPNIKNVAYttltDAKGNFYYIPSNSKtSLKVHLKDQNSKTD----DGKTDTTGRYATAWFDHSTSPSNDKYQYAVL 997 77777888888888999855666677776632255555555554443....467999**********************986 PP == domain 2 score: -3.3 bits; conditional E-value: 1.1 Lyase_8 121 stltakKsWfflddeivalg 140 + ++ K+W l +++v++g FUN_001763-T1 1035 QFVKSPKTWTALGNDYVVTG 1054 45677799999999999987 PP >> Lyase_catalyt Lyase, catalytic # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.7 0.1 3.4e-31 2.2e-27 122 331 .. 419 644 .. 401 675 .. 0.81 Alignments for each domain: == domain 1 score: 96.7 bits; conditional E-value: 3.4e-31 Lyase_catalyt 122 amldhltDqGvayGsglgtiHHyGYslrkly.vsalLmkdvlrkeg...kleeaertlrwyaalnevyrkPlpessD..lDsfntllsgklasill 211 ++ld+++DqG+a+Gsglg++ H + + s lL+ d l+++ kl + +t +wy +evy+ P e + D t l+ +++ +l+ FUN_001763-T1 419 HLLDYVKDQGFADGSGLGSLDHEMNRVGAGFsHSLLLLSDSLNEASnktKLLDLIETAKWYNDFGEVYQSPAFEYKGttADRMITILHFRVMIVLV 514 579*****************999998876662688999****9875111566778999*************976544449**************** PP Lyase_catalyt 212 medspek.....lqyLkslsrwldvglrpakgllgslkvDGaafhHennYP.aYavgglkgitqliyllsgtsfalseearetvkkalLamrfYcn 301 m+ s ++ ++ + + rw++ + + + g +k+D + fhH+ Y aY +l+ ++ + y l+gt+f lse + ++++ l +r + FUN_001763-T1 515 MPKSTDQekkarIRDMDAIVRWMNNAFAVNDAFGGVIKPDYTGFHHKAIYGsAYVPQALQVAGLVKYFLHGTKFSLSETSVNNIRRGLEVIRLMAA 610 99876541111144567789******************************63899999************************************** PP Lyase_catalyt 302 klewplslsGRHPdgskkltdl....ayallAla 331 k++ p s+ GR P+ s+k+ ya++ +a FUN_001763-T1 611 KYSSPNSINGRFPNYSNKVLIKaalgGYAYFSVA 644 **************99887554355667777765 PP >> Lyase_N Lyase, N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.0 0.1 2.3e-19 1.5e-15 2 165 .. 45 213 .. 44 214 .. 0.83 2 ? -3.4 0.1 1.8 1.1e+04 36 69 .. 229 266 .. 227 269 .. 0.75 Alignments for each domain: == domain 1 score: 58.0 bits; conditional E-value: 2.3e-19 Lyase_N 2 ervisFeekqlpefvk....asskselslssahykdGkqsLeWefqpqstlslkkelkleakdktekdl.glkafklWvynEkpq.ddsivfefld 91 ++v++Fe + ++++ s + +ls s++ k G++sL+W+ + s sl+ + + + ++ k++ + +k+W+y + + ++++ ef d FUN_001763-T1 45 NQVFDFETSAEADCFQlvpvGSGTKTLSSSKNTVKFGQKSLKWHATSTSPSSLQLD--FATGHHITKSWlERGGVKVWLYKDSASpGKQLKAEFKD 138 689****9999888875433456778999999************999999999888..888777777662566789*****98863689******* PP Lyase_N 92 kdGkvsasfkfklnfkGWRavwvsyer....dlegkkekdidelrvvaPevkgrlfiDrlilaekvdarqqtpDaqvp 165 + k + fk +lnfkGWR++wv +++ ++++ i+ + ++ P k ++iD l +++ +qt D+ vp FUN_001763-T1 139 TNDKIFCLFKANLNFKGWRGIWVKFSEckpsGISVTSSSTINRVLFTIPG-KVTIYIDILEFKNSLG--KQTRDKIVP 213 **************************965555566788999999999994.457******9999855..888888776 PP == domain 2 score: -3.4 bits; conditional E-value: 1.8 Lyase_N 36 qsLeWefqpq....stlslkkelkleakdktekdlglk 69 +s +W+ qp+ st+++ k+l+l+ ++ +++l FUN_001763-T1 229 RSYHWSQQPApdlpSTVDVTKNLHLDVIKSRMMNWYLD 266 68888888865555889999999998888888888876 PP >> CobW_C_DAAF9 DAAF9 CobW_C-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.1 0.79 5.1e+03 8 24 .. 394 410 .. 392 413 .. 0.89 2 ? -3.5 0.0 2.3 1.5e+04 30 54 .. 756 783 .. 750 784 .. 0.67 3 ? 11.2 0.0 5.7e-05 0.36 24 67 .. 1037 1083 .. 1025 1085 .. 0.79 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.79 CobW_C_DAAF9 8 srPLerklfvaklkalk 24 s+PL +++ +++kal FUN_001763-T1 394 SKPLTKNQVKNAIKALN 410 79************996 PP == domain 2 score: -3.5 bits; conditional E-value: 2.3 CobW_C_DAAF9 30 sPfkGNiYni...kGkvrFsdsdklmeV 54 P k NiY + +G + +s+ l+ V FUN_001763-T1 756 QPNKENIYGLyasHGALLIANSEALLSV 783 5666777654333888888888888776 PP == domain 3 score: 11.2 bits; conditional E-value: 5.7e-05 CobW_C_DAAF9 24 kssLkpsPfkGNiYnikGkvrFsdsdkl...meVsyntlsgsLsvvk 67 +s k++ GN Y+++G+v F + +l e++++t ++ L +v+ FUN_001763-T1 1037 VKSPKTWTALGNDYVVTGYVVFRGNLNLprrGEIKHVTAKDVLLMVE 1083 5666899999************9865442228*********998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 898 (0.0351537); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.44u 0.42s 00:00:00.86 Elapsed: 00:00:00.43 # Mc/sec: 11001.85 // Query: FUN_001764-T1 [L=239] Description: FUN_001764 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-29 102.0 5.9 2.2e-26 94.0 0.7 2.1 2 Neur_chan_memb Neurotransmitter-gated ion-channel transmemb 2.3e-09 37.5 0.1 3.1e-09 37.1 0.1 1.2 1 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand bi ------ inclusion threshold ------ 0.012 15.7 1.4 1.5 9.0 0.1 2.7 2 RhodobacterPufX Intrinsic membrane protein PufX 0.15 11.4 2.2 0.22 10.9 2.2 1.2 1 EccD EccD-like transmembrane domain 0.24 12.4 0.5 0.54 11.2 0.2 1.7 2 DUF3681 Protein of unknown function (DUF3681) 0.7 9.8 5.2 3.3 7.6 3.3 2.0 2 DUF2417 Region of unknown function (DUF2417) Domain annotation for each model (and alignments): >> Neur_chan_memb Neurotransmitter-gated ion-channel transmembrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 94.0 0.7 5.2e-30 2.2e-26 1 109 [. 74 181 .. 74 193 .. 0.93 2 ! 11.0 0.4 0.00012 0.53 199 233 .] 200 233 .. 188 233 .. 0.80 Alignments for each domain: == domain 1 score: 94.0 bits; conditional E-value: 5.2e-30 Neur_chan_memb 1 liiPcvliviLsvlvFyLpadavgekvtLgItvlLtlTvflllireslPktSlvvpligkYLlfcmvfvflslvetviVlnvhhrspsthkmsew 95 li+P+++i+ + + F+Lp+++ ge++ LgItvlL++ vfl l+ + lP+tS + pl+gk+ +++m + lsl t Vln+ + +m++w FUN_001764-T1 74 LIVPALIITAMVLVGFFLPPES-GERMQLGITVLLAMIVFLQLVYQNLPSTSNSAPLLGKFYIITMFLISLSLAATCLVLNYWYGRHGDGEMPMW 167 69********************.***********************************************************99555668***** PP Neur_chan_memb 96 vrklfleklprlll 109 vr + l+ l r+ + FUN_001764-T1 168 VRLIILDCLGRVFG 181 ****9999887765 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00012 Neur_chan_memb 199 keevkedwklvakviDrlsliifpivfvlgtlvif 233 ++ +++wk++a+ +D++++++f +++ + + +f FUN_001764-T1 200 VSK-ENEWKTAANILDKFFMAFFAFLITITAISLF 233 444.455******************9999887766 PP >> Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.1 0.1 7.2e-13 3.1e-09 142 215 .. 1 66 [. 1 67 [. 0.95 Alignments for each domain: == domain 1 score: 37.1 bits; conditional E-value: 7.2e-13 Neur_chan_LBD 142 lkfeSwtynkeevdlewkkekkvveeeeidlsdflengewelveveakreekktgsyselsysdvtftltlrRk 215 +kf+Swt++++ vd+++ + + ++e gew+l +++ kr++k+++++ ++ y d+t+t++lrR+ FUN_001764-T1 1 MKFGSWTHDESRVDMRIFG-------NASNDDIYTEHGEWQLLSINQKRTSKMYDCCPKP-YVDITYTIHLRRR 66 89***************99.......6788899**************************9.8***********8 PP >> RhodobacterPufX Intrinsic membrane protein PufX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.2 0.0063 27 35 56 .. 74 95 .. 68 98 .. 0.83 2 ? 9.0 0.1 0.00035 1.5 34 60 .. 102 128 .. 100 132 .. 0.92 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0063 RhodobacterPufX 35 vlvllflivalaliGrlLPeqs 56 ++v ++i a+ l+G LP +s FUN_001764-T1 74 LIVPALIITAMVLVGFFLPPES 95 5566789************998 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00035 RhodobacterPufX 34 fvlvllflivalaliGrlLPeqsrqaP 60 ++ vll +iv+l+l+ + LP s++aP FUN_001764-T1 102 GITVLLAMIVFLQLVYQNLPSTSNSAP 128 567999********************9 PP >> EccD EccD-like transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 2.2 5.2e-05 0.22 250 328 .. 72 151 .. 60 159 .. 0.76 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 5.2e-05 EccD 250 lallvaGllglalllvglalaaspaarllvlvglllvaaa.lllvaglvlpgrrlsPywgRaaDiletllivavvPlala 328 l l+v++l+++a++lvg++l +++ r+ + + +ll++ + l lv+ ++ + P +g++ i+ +l+ +++ +l FUN_001764-T1 72 LYLIVPALIITAMVLVGFFLPPESGERMQLGITVLLAMIVfLQLVYQNLPSTSNSAPLLGKFYIITMFLISLSLAATCLV 151 789****************9996666665555444444441578888888899999****99988888777777666654 PP >> DUF3681 Protein of unknown function (DUF3681) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.2 0.00013 0.54 32 89 .. 61 116 .. 58 118 .. 0.85 2 ? -2.7 0.0 2.8 1.2e+04 68 81 .. 155 168 .. 129 176 .. 0.61 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00013 DUF3681 32 vflrgkallyayygilvavvlfGvaevavglwvsgdperRravGktvlwvsvvplvlv 89 + lr ++l+y+ y+i+ a ++ a v vg+++ + +R ++G tvl + +v l lv FUN_001764-T1 61 IHLRRRSLFYTLYLIVPALIIT--AMVLVGFFLPPESGERMQLGITVLLAMIVFLQLV 116 5567888999999998888775..67899*******99***********999977665 PP == domain 2 score: -2.7 bits; conditional E-value: 2.8 DUF3681 68 perRravGktvlwv 81 +R++ G++ +wv FUN_001764-T1 155 WYGRHGDGEMPMWV 168 33566666666666 PP >> DUF2417 Region of unknown function (DUF2417) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 3.3 0.00077 3.3 71 151 .. 63 146 .. 53 160 .. 0.70 2 ? 2.1 0.0 0.036 1.5e+02 29 68 .. 199 237 .. 181 239 .] 0.63 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.00077 DUF2417 71 hnrgsgFldlalttlslvtlllnllffsvpsklerilnivlavLllvdlililavkrl...ReeegwvgiasvvWalltfllgv 151 r s F+ l l++ +l+++++ l+ f +p ++ +++ ++vLl++ ++l l+ ++l + ++g + ++ +l++l + FUN_001764-T1 63 LRRRSLFYTLYLIVPALIITAMVLVGFFLPPESGERMQLGITVLLAMIVFLQLVYQNLpstSNSAPLLGKFYIITMFLISLSLA 146 457778999999999*********999999999999999888888888888887766500055555566665555555554443 PP == domain 2 score: 2.1 bits; conditional E-value: 0.036 DUF2417 29 avspynlwsvrllrwllvvlllitfiwwvlllvsdFvspp 68 +vs++n w++ + +l +++++ ++ +++ +s+F++ p FUN_001764-T1 199 DVSKENEWKT-AANILDKFFMAFFAFLITITAISLFFQAP 237 5788888866.33444444444444555666677777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (239 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1191 (0.0466236); expected 510.9 (0.02) Passed bias filter: 612 (0.0239577); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2359.29 // Query: FUN_001765-T1 [L=107] Description: FUN_001765 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-17 62.7 0.5 6.1e-17 62.0 0.2 1.5 2 CD225 Interferon-induced transmembrane protein ------ inclusion threshold ------ 0.011 16.4 0.1 0.016 15.8 0.1 1.2 1 DUF4064 Protein of unknown function (DUF4064) 0.035 14.9 0.5 0.061 14.1 0.5 1.4 1 DUF456 Protein of unknown function (DUF456) 0.084 13.2 0.0 0.12 12.7 0.0 1.2 1 EssA WXG100 protein secretion system (Wss), protein EssA 0.38 11.0 5.4 22 5.4 0.0 2.2 2 DUF4190 Domain of unknown function (DUF4190) 0.61 10.7 10.7 1.5 9.4 0.0 2.4 2 MpPF26 M penetrans paralogue family 26 Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 62.0 0.2 1.4e-20 6.1e-17 1 67 [. 29 94 .. 29 96 .. 0.95 2 ? -0.4 0.2 0.44 1.9e+03 13 23 .. 92 102 .. 89 104 .. 0.58 Alignments for each domain: == domain 1 score: 62.0 bits; conditional E-value: 1.4e-20 CD225 1 pPkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviiil 67 pP+d+ ++si+s++f c plG++Al +S+ +++r++a++++ Aq+as+ A++ +i+++++g i+++ FUN_001765-T1 29 PPNDHRILSIVSIFF-CPPLGFLALLMSYVTNQRYEADEMKRAQDASKDARFSAILAIIFGCSIVFF 94 79************8.899******************************************988765 PP == domain 2 score: -0.4 bits; conditional E-value: 0.44 CD225 13 tlfcclplGiv 23 ++fc++++ iv FUN_001765-T1 92 VFFCIFIFTIV 102 34466666665 PP >> DUF4064 Protein of unknown function (DUF4064) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.8 0.1 3.9e-06 0.016 6 76 .. 34 102 .. 31 105 .. 0.62 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 3.9e-06 DUF4064 6 fiLglIGgilgillgllaliflfligsgeasqelte..gaasgedasatlsifstlllvliiialiaiilgiv 76 iL+++++ + lg+lal++ +++++ ++++e+ a ++ sa+l+i+ + +v++ i++++ iv FUN_001765-T1 34 RILSIVSIFFCPPLGFLALLMSYVTNQRYEADEMKRaqDASKDARFSAILAIIFGCSIVFFCIFIFT----IV 102 7999999999999999999998888887777776644333333333444444444444444444444....43 PP >> DUF456 Protein of unknown function (DUF456) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.5 1.4e-05 0.061 69 136 .. 35 100 .. 34 106 .. 0.59 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.4e-05 DUF456 69 vgaivGffllpplGlllgpflgallgEllrarkdlreAlkaavgalvgfllgtlvklllallmivlfl 136 + iv +f+ pplG+l +l +++ ++ +++++A a+ a + +l +++ + +++i++f FUN_001765-T1 35 ILSIVSIFFCPPLGFLA--LLMSYVTNQRYEADEMKRAQDASKDARFSAILAIIFGCSIVFFCIFIFT 100 5789**********985..4445555545555566666666655555555555554444444444443 PP >> EssA WXG100 protein secretion system (Wss), protein EssA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 2.9e-05 0.12 106 144 .. 67 103 .. 56 105 .. 0.81 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.9e-05 EssA 106 vkqsstEeeeaessssvllllliavvivlliiglivlip 144 +k +++ +++ + s +l ++++ iv ++i +++++p FUN_001765-T1 67 MKRAQD--ASKDARFSAILAIIFGCSIVFFCIFIFTIVP 103 344434..6899999**********************99 PP >> DUF4190 Domain of unknown function (DUF4190) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.0051 22 7 34 .. 35 62 .. 35 71 .. 0.83 2 ? 2.8 6.3 0.033 1.4e+02 2 24 .. 81 104 .. 80 106 .. 0.90 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.0051 DUF4190 7 VlgilglllliilgivaiilGhvAlrqi 34 +l+i++++++ +lg +a+ + +v ++ FUN_001765-T1 35 ILSIVSIFFCPPLGFLALLMSYVTNQRY 62 6899**999889999**99999877665 PP == domain 2 score: 2.8 bits; conditional E-value: 0.033 DUF4190 2 AiasLVlgilgllll.iilgivai 24 Ai+++++g+ ++++ +i+ iv + FUN_001765-T1 81 AILAIIFGCSIVFFCiFIFTIVPV 104 9**********9999999999987 PP >> MpPF26 M penetrans paralogue family 26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.0 0.00036 1.5 53 71 .. 33 51 .. 28 55 .. 0.85 2 ? 1.3 8.4 0.12 5.1e+02 8 28 .. 85 102 .. 77 105 .. 0.62 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00036 MpPF26 53 gkiLlIiGivlspiliiis 71 ++iL I+ i+++p l++ + FUN_001765-T1 33 HRILSIVSIFFCPPLGFLA 51 9************998765 PP == domain 2 score: 1.3 bits; conditional E-value: 0.12 MpPF26 8 lIlvlclvgfvgiiigIlaiv 28 +I+++++ v+++i+I++iv FUN_001765-T1 85 IIFGCSI---VFFCIFIFTIV 102 4556665...55666776666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 964 (0.0377373); expected 510.9 (0.02) Passed bias filter: 643 (0.0251713); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1067.67 // Query: FUN_001766-T1 [L=101] Description: FUN_001766 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.022 15.4 0.3 0.044 14.5 0.3 1.5 1 CD225 Interferon-induced transmembrane protein 0.078 13.4 0.0 0.12 12.8 0.0 1.3 1 DUF6203 Family of unknown function (DUF6203) 0.17 11.9 0.0 0.18 11.8 0.0 1.0 1 DtrJ-like IncC plasmid conjugative DNA transfer protein DtrJ 2.6 8.3 6.0 23 5.3 5.9 2.0 1 DUF4190 Domain of unknown function (DUF4190) Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.3 6.9e-06 0.044 7 66 .. 30 86 .. 25 92 .. 0.80 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 6.9e-06 CD225 7 vwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviii 66 v++ + tl +p+Giv +v+ + +r++ +G ++ ++ +A + +++s+ +gl ++ FUN_001766-T1 30 VLTSLLTL---FPIGIVSIVFWILARKAGGRGSKRQEAENYHEAETMALTSISFGLCAVL 86 44444455...59****************9999887777779999999999999987765 PP >> DUF6203 Family of unknown function (DUF6203) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 1.9e-05 0.12 7 47 .. 29 68 .. 27 74 .. 0.78 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.9e-05 DUF6203 7 lvvarrLarTPiGlvvlgvgWlLarrrrrraaeregaaqar 47 lv++ L+ PiG+v + v W+Lar+ r +r+ a++ + FUN_001766-T1 29 LVLTSLLTLFPIGIVSI-VFWILARKAGGRGSKRQEAENYH 68 688888999****9987.88*****9988886666665555 PP >> DtrJ-like IncC plasmid conjugative DNA transfer protein DtrJ-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 2.8e-05 0.18 90 166 .. 11 87 .. 1 93 [. 0.88 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 2.8e-05 DtrJ-like 90 syleaallvvytflvRlavlllalplflllalvalvDGlvrRdlrrfgagressfvyhhakhlliplvvvplllyLa 166 +y ea + + + vR a++l++l+ ++ +++v +v + R++ g +r+ + yh a+ ++ + +l ++L FUN_001766-T1 11 KYQEARKKLLFSDGVRTALVLTSLLTLFPIGIVSIVFWILARKAGGRGSKRQEAENYHEAETMALTSISFGLCAVLT 87 67777777778888************************************************999999999988885 PP >> DUF4190 Domain of unknown function (DUF4190) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 5.9 0.0036 23 5 57 .. 28 86 .. 26 91 .. 0.67 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0036 DUF4190 5 sLVlgilglllliilgivaiilGhvAlrqirrtg........erGkglAiaGivlGwigla 57 +LVl l l+ ++giv i++ ++A++ r + +++A++ i G +++ FUN_001766-T1 28 ALVLTSLLTLF--PIGIVSIVFWILARKAGGRGSkrqeaenyHEAETMALTSISFGLCAVL 86 67776665555..999999999999987654443333344556777888888888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 909 (0.0355843); expected 510.9 (0.02) Passed bias filter: 687 (0.0268937); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1017.32 // Query: FUN_001767-T1 [L=146] Description: FUN_001767 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-17 64.3 2.1 1.8e-17 63.8 2.1 1.2 1 CD225 Interferon-induced transmembrane protein ------ inclusion threshold ------ 0.023 15.4 1.9 0.14 12.9 0.6 1.9 2 L_HMGIC_fpl Lipoma HMGIC fusion partner-like protein 0.1 13.3 0.1 0.24 12.1 0.1 1.5 1 DUF2964 Protein of unknown function (DUF2964) 0.15 12.8 1.7 0.33 11.7 1.7 1.8 1 Comm Commissureless Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.8 2.1 2.8e-21 1.8e-17 2 67 .. 65 130 .. 64 131 .. 0.98 Alignments for each domain: == domain 1 score: 63.8 bits; conditional E-value: 2.8e-21 CD225 2 PkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviiil 67 P+++++++++stlfc +p+G++ l y++kv++ a+G+le+A ++s++A ++ +is+ +g +ii++ FUN_001767-T1 65 PQNHMMLAVLSTLFCACPCGLASLLYAMKVNSTHAQGNLEAALYNSKQAWKYGMISVAIGCAIITV 130 99*************************************************************987 PP >> L_HMGIC_fpl Lipoma HMGIC fusion partner-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.1 0.025 1.6e+02 34 97 .. 31 93 .. 19 100 .. 0.76 2 ? 12.9 0.6 2.1e-05 0.14 51 98 .. 95 142 .. 82 146 .] 0.80 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.025 L_HMGIC_fpl 34 kagslglyerCkvesqevelecgrsaldflaipssafkaaavfvalgill.llvvvllsllvlck 97 +++ l+ly + ++ ++++ +++++ + i+s + +++ +l++l + l sll +k FUN_001767-T1 31 RSTVLALYPTTQ--QSGHDMTSAGTQSNERVINSDLPQNHMMLAVLSTLFcACPCGLASLLYAMK 93 456678888877..556778888888899999999999999999999888677777777877776 PP == domain 2 score: 12.9 bits; conditional E-value: 2.1e-05 L_HMGIC_fpl 51 velecgrsaldflaipssafkaaavfvalgillllvvvllsllvlckq 98 ++++++ + l +a+k ++ va+g+++++vv++ l+ + +q FUN_001767-T1 95 NSTHAQGNLEAALYNSKQAWKYGMISVAIGCAIITVVMCYYLILVSQQ 142 5566667777777777889*********************99988764 PP >> DUF2964 Protein of unknown function (DUF2964) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 3.7e-05 0.24 29 55 .. 106 132 .. 100 135 .. 0.86 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.7e-05 DUF2964 29 sLfdldaellyGviaiaiGvaacvvlL 55 L++ ++ +yG+i +aiG a + v++ FUN_001767-T1 106 ALYNSKQAWKYGMISVAIGCAIITVVM 132 79*****************99887765 PP >> Comm Commissureless # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 1.7 5.2e-05 0.33 15 48 .. 68 101 .. 54 141 .. 0.72 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 5.2e-05 Comm 15 vltLlilslvFcicsCflyhkfrtWkksvranks 48 ++L +ls++Fc c C l k + +++ FUN_001767-T1 68 HMMLAVLSTLFCACPCGLASLLYAMKVNSTHAQG 101 5899**************7765555544444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (146 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 990 (0.0387551); expected 510.9 (0.02) Passed bias filter: 585 (0.0229008); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1462.38 // Query: FUN_001768-T1 [L=169] Description: FUN_001768 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-42 145.1 0.2 2e-42 144.9 0.2 1.0 1 DUF1757 Protein of unknown function (DUF1757) ------ inclusion threshold ------ 0.15 12.3 4.3 0.34 11.2 4.3 1.6 1 DUF8141 Domain of unknown function (DUF8141) Domain annotation for each model (and alignments): >> DUF1757 Protein of unknown function (DUF1757) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 144.9 0.2 1.6e-46 2e-42 1 147 [. 7 160 .. 7 161 .. 0.95 Alignments for each domain: == domain 1 score: 144.9 bits; conditional E-value: 1.6e-46 DUF1757 1 wlknflgfklsdeelaeiprPrvElaihvtfksveagallGslivgPlvrlllkkkltskkkireafvklgkrgallGlvlGPvltllklr...nl 93 w++n++g+kl dee+ +i++Pr+El+ hvtfk+++agallG+++++P+vrl+ ++ + ++i e+++++g++gal+G+ lGP++t+ +++ +l FUN_001768-T1 7 WFRNMMGQKLADEEMGQIKYPRMELYAHVTFKTIQAGALLGMVLIAPAVRLVSGPR--TLNAISETALRYGRNGALIGIPLGPLMTYGRATsgdGL 100 ********************************************************..8*****************************9987889* PP DUF1757 94 seeelydkcYrlRfneeqlrlDRaavlsaavG.ylk......sgfqGavvGldlalllsll 147 +e+ d++YrlR+n++q+r+D+a++++++ G s ++GavvGl +++++ + FUN_001768-T1 101 NEDGFIDRAYRLRYNRNQVRVDQASIVGTLGGaG-VavllgsSAVSGAVVGLVGGTVAMGM 160 ****************************999953.34789999************998876 PP >> DUF8141 Domain of unknown function (DUF8141) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 4.3 2.7e-05 0.34 26 63 .. 126 163 .. 123 167 .. 0.90 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 2.7e-05 DUF8141 26 plGfaaGYllapslgvdpllggvyGlvaaslplsLlvv 63 ++G ++G +a+ lg + g+v+Glv++++ ++++ + FUN_001768-T1 126 IVGTLGGAGVAVLLGSSAVSGAVVGLVGGTVAMGMYNT 163 6789999999*************************966 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (169 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 541 (0.0211783); expected 510.9 (0.02) Passed bias filter: 347 (0.0135839); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.34s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1702.71 // Query: FUN_001769-T1 [L=208] Description: FUN_001769 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-18 66.6 0.6 3.6e-18 66.0 0.6 1.3 1 CD225 Interferon-induced transmembrane protein ------ inclusion threshold ------ 0.058 13.9 0.9 0.09 13.3 0.9 1.3 1 MpPF26 M penetrans paralogue family 26 4.1 7.7 10.9 13 6.1 4.4 2.2 2 DUF4190 Domain of unknown function (DUF4190) Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.0 0.6 4.3e-22 3.6e-18 2 66 .. 127 192 .. 126 194 .. 0.94 Alignments for each domain: == domain 1 score: 66.0 bits; conditional E-value: 4.3e-22 CD225 2 Pkdylvwsifstlf.cclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviii 66 P+++l+++i +++ cc ++Giv ++++++v++++ +G+ egA s++Ak+l++i++v+g++ ++ FUN_001769-T1 127 PDNHLCLAITGMICcCCPIIGIVGFIFAMQVDKAYDDGNREGAVWRSKNAKCLSLIAVVFGMMAFV 192 9*************666689*****************************************99875 PP >> MpPF26 M penetrans paralogue family 26 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.9 1.1e-05 0.09 10 66 .. 138 189 .. 131 200 .. 0.80 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.1e-05 MpPF26 10 lvlclvgfvgiiigIlaivLaiKisklkkknpeyykgfknvktgkiLlIiGivlspi 66 +++c+ + iigI++ ++a+ + k++ + + ++ k+ k L +i++v+ ++ FUN_001769-T1 138 MICCC----CPIIGIVGFIFAMQVDKAYDDGNREGA-VWRSKNAKCLSLIAVVFGMM 189 44555....7899****************9999666.8889999*********9544 PP >> DUF4190 Domain of unknown function (DUF4190) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 4.4 0.0016 13 6 28 .. 131 152 .. 130 171 .. 0.72 2 ? 5.7 0.6 0.002 17 18 30 .. 178 190 .. 168 194 .. 0.87 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0016 DUF4190 6 LVlgilglllliilgivaiilGh 28 L+l+i+g++++ +++i++i+ + FUN_001769-T1 131 LCLAITGMICC-CCPIIGIVGFI 152 89999999994.77777776333 PP == domain 2 score: 5.7 bits; conditional E-value: 0.002 DUF4190 18 ilgivaiilGhvA 30 +l+++a+++G++A FUN_001769-T1 178 CLSLIAVVFGMMA 190 689*********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 946 (0.0370327); expected 510.9 (0.02) Passed bias filter: 650 (0.0254453); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2087.62 // Query: FUN_001770-T1 [L=111] Description: FUN_001770 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.028 15.6 1.7 0.028 15.6 1.7 1.8 2 Hydrophobin Fungal hydrophobin 0.077 13.1 1.2 0.11 12.6 1.1 1.5 1 PTPLA Protein tyrosine phosphatase-like protein, PTPLA Domain annotation for each model (and alignments): >> Hydrophobin Fungal hydrophobin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 1.7 2.2e-06 0.028 23 76 .. 4 59 .. 1 60 [. 0.75 2 ? -0.3 0.1 0.19 2.5e+03 59 75 .. 81 96 .. 78 98 .. 0.78 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 2.2e-06 Hydrophobin 23 lgllgivledltglvgltCspis..vvgvgggssCkaqpvCCennsfng.lvnlgCt 76 l+ll ++++++++ g+t ++ s v + C +++ CC++n+ + v+l+C+ FUN_001770-T1 4 LELLTDETQNVHKKTGITAQRNSfsDVI-WSFCDCVSSIYCCQSNQEGTpHVELKCM 59 6777778899998888887766532332.34689*************6679*****7 PP == domain 2 score: -0.3 bits; conditional E-value: 0.19 Hydrophobin 59 pvCCennsfnglvnlgC 75 + CC + +lv + C FUN_001770-T1 81 TFCCIYDKV-TLVDFAC 96 689988888.7888888 PP >> PTPLA Protein tyrosine phosphatase-like protein, PTPLA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 1.1 8.4e-06 0.11 68 106 .. 62 99 .. 29 110 .. 0.83 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 8.4e-06 PTPLA 68 yalsllgkevpklltwlRYtlfivLYPlGvlsEllliyk 106 ya+++++ ++pk wlRY++f +Y l ++ ++++ FUN_001770-T1 62 YATAIFT-TMPKHPFWLRYSTFCCIYDKVTLVDFACLWN 99 5555555.666888************8887777777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (111 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 688 (0.0269329); expected 510.9 (0.02) Passed bias filter: 352 (0.0137796); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1122.53 // Query: FUN_001771-T1 [L=499] Description: FUN_001771 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.8e-46 157.1 0.7 1.1e-45 156.6 0.7 1.1 1 Beta-prop_WDR5 WDR5 beta-propeller domain 5.3e-35 121.5 0.1 7.7e-20 71.7 0.1 3.1 3 WD40_WDHD1_1st WDHD1 first WD40 domain 7.7e-35 118.3 7.6 1.1e-06 29.4 0.1 5.9 5 WD40 WD domain, G-beta repeat 1.4e-34 119.9 0.5 1.6e-28 100.1 1.0 3.0 3 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 9.5e-34 117.1 0.2 7.4e-15 55.2 0.2 3.5 2 Beta-prop_THOC3 THOC3 beta-propeller domain 1.9e-33 116.3 4.8 1.9e-19 70.4 0.4 2.4 2 WDR55 WDR55 1.3e-30 107.2 3.3 8.7e-15 55.3 0.3 3.1 3 Beta-prop_EML_2 Echinoderm microtubule-associated 1.1e-28 100.6 0.2 2.5e-16 60.1 0.1 2.3 2 WD40_Prp19 Prp19 WD40 domain 2.1e-24 86.9 1.0 7.7e-23 81.8 0.8 2.7 2 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 1.2e-23 84.1 2.6 7.6e-18 65.1 1.1 3.2 3 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 1.2e-22 81.2 2.7 3.1e-10 40.4 0.1 3.2 4 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 3.3e-22 79.6 0.3 7.7e-20 71.8 0.3 2.7 1 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 1.4e-21 77.5 1.5 3.6e-21 76.2 1.4 1.8 1 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 2e-18 67.1 1.4 1e-09 38.5 0.1 3.1 3 EIF3I EIF3I 2.1e-16 60.3 1.1 5.6e-09 35.9 0.0 3.0 2 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 5.1e-16 59.2 0.0 3.7e-05 24.3 0.0 4.5 6 ANAPC4_WD40 Anaphase-promoting complex subunit 5.3e-15 55.7 4.2 3.2e-08 33.5 0.5 3.3 3 WD40_Gbeta G protein beta WD-40 repeat protei 2.8e-14 53.4 0.1 1.9e-09 37.5 0.1 2.8 2 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 7.9e-14 51.5 0.0 1.5e-13 50.6 0.0 1.5 1 LisH_TPL LisH-like dimerisation domain 1.6e-13 51.0 0.8 3.8e-05 23.5 0.0 3.2 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 7e-13 49.1 1.8 9.9e-08 32.3 0.1 3.0 3 Beta-prop_EML Echinoderm microtubule-associated 3.2e-12 47.0 2.8 5.2e-10 39.7 1.2 2.1 2 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 3.5e-11 43.2 0.9 5.4e-06 26.1 0.0 3.2 3 Beta-prop_VPS8 Vps8 beta-propeller 1.3e-10 41.7 0.0 2.7e-06 27.5 0.2 4.4 2 Beta-prop_RIG_2nd RIG second beta-propeller 1.6e-10 41.3 0.7 1.7e-05 24.8 0.0 2.5 3 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 3.8e-10 39.6 0.3 0.00031 20.1 0.1 2.9 3 Beta-prop_WDR41 WDR41 6.5e-10 39.3 0.0 5.6e-06 26.3 0.0 2.1 2 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller 8.7e-10 38.7 0.3 1.3e-05 24.9 0.0 2.4 2 WDR90_beta-prop_4th WDR90, 4th beta-propeller 2.1e-09 37.2 2.4 0.017 14.4 1.9 4.0 5 NBCH_WD40 Neurobeachin beta propeller domain 1.3e-08 34.6 0.0 9.6e-05 21.9 0.0 3.0 3 Beta-prop_SPT8 SPT8 beta propeller 1.5e-08 34.5 0.8 0.0069 15.9 0.1 3.3 3 Ge1_WD40 WD40 region of Ge1, enhancer of mR 2.3e-08 34.2 1.6 0.0001 22.2 0.1 3.6 4 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 3.5e-08 33.2 0.3 0.00037 20.0 0.0 3.1 3 Beta-prop_IFT122_1st IFT122 first beta-propeller 5.1e-08 32.7 2.7 0.00011 21.7 0.4 2.6 2 Beta-prop_SCAP SCAP Beta-propeller 9e-08 32.2 0.8 0.16 11.7 0.0 3.5 3 Beta-prop_Vps41 Vps42 beta-propeller 2.2e-07 30.7 0.0 0.001 18.7 0.0 2.7 2 Beta-prop_WDR19_1st WDR19 first beta-propeller 3.1e-07 30.8 0.1 0.0014 19.1 0.1 3.5 3 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 3.4e-07 29.8 0.1 0.0096 15.1 0.1 2.9 3 Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-prope 1e-06 28.4 0.0 0.12 11.8 0.0 2.8 2 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 2.1e-06 27.6 0.1 6.7e-05 22.6 0.1 3.0 3 Beta-prop_Aladin Aladin seven-bladed propeller 2.5e-06 27.5 0.3 2.3e-05 24.3 0.0 2.0 2 Beta-prop_HPS5 HPS5 beta-propeller 3e-06 27.1 0.1 1.8e-05 24.6 0.1 2.1 2 Beta-prop_NWD2_C NWD2 C-terminal beta-propeller 3.4e-05 23.9 0.1 9.4e-05 22.5 0.1 1.7 1 Beta-prop_EIPR1 EIPR1 beta-propeller 6.1e-05 22.4 0.1 0.011 15.0 0.0 3.4 3 Beta-prop_IFT140_1st IFT140 first beta-propeller 0.00011 22.0 0.2 0.86 9.2 0.1 3.2 3 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 0.00016 21.2 0.8 0.11 11.8 0.0 2.3 2 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 0.0004 20.3 0.4 0.0018 18.1 0.4 2.1 1 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 0.0012 18.7 0.1 5.6 6.6 0.0 2.9 2 Beta-prop_BBS7 BBS7 beta-propeller 0.0056 16.1 0.6 0.36 10.1 0.1 2.3 2 Beta-prop_IP5PC_F IP5P C-F beta-propeller ------ inclusion threshold ------ 0.011 15.3 0.4 0.058 12.9 0.0 2.0 3 Beta-prop_LRRK2 LRRK2 beta propeller 0.013 15.4 0.0 0.48 10.2 0.0 2.3 2 WD40_like WD40-like domain 0.017 14.4 0.0 0.16 11.2 0.0 2.0 2 DUF7165 Domain of unknown function (DUF716 0.026 15.0 0.0 3 8.4 0.0 2.9 3 RMC1_N Regulator of MON1-CCZ1 complex, N- 0.043 13.1 0.3 0.21 10.8 0.3 2.1 1 Beta-prop_WDR75_2nd WD repeat-containing protein 75 se 0.082 12.6 0.1 6.1 6.5 0.1 2.7 1 KNTC1_N KNTC1, N-terminal 0.097 12.8 0.8 17 5.4 0.0 3.3 3 Hira TUP1-like enhancer of split 0.13 12.0 0.2 2.4 7.8 0.2 2.4 1 Beta-prop_RSE1_2nd RSE1/DDB1/CPSF1 second beta-propel 0.2 11.3 0.2 6.3 6.3 0.0 2.3 2 Beta-prop_IFT140_2nd IFT140 second beta-propeller Domain annotation for each model (and alignments): >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 156.6 0.7 2.5e-48 1.1e-45 9 259 .. 217 481 .. 209 489 .. 0.87 Alignments for each domain: == domain 1 score: 156.6 bits; conditional E-value: 2.5e-48 Beta-prop_WDR5 9 vssvkfspdgkllasasaDktikiwdveegklektleghkk........GisdvawssdskllasaSDDktvriwdvetgkllktl.kgHtnyvf 94 +vkfspdg++l + s D+ i++++ ++gk+ k l+ +++ + +a+s+ds++las+ D ++++w+v+tg++l+ + k H + ++ FUN_001771-T1 217 PECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAQdnfmmmddSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFeKAHAKGIT 311 579****************************999998765433333333999*********************************9457****** PP Beta-prop_WDR5 95 cvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliriwdtetgqclktlved.....dnppvsfvkFs 184 cv+F+ + + l+SGsfD t+r+ +++gk+lk + +H+ v f+ d++ i+s+s Dg +++w+++t +cl+t+ ++ v +v+ FUN_001771-T1 312 CVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAvgsvaTDITVNSVHLM 406 ****************************************************************************7432222244599999999 PP Beta-prop_WDR5 185 p.ngkyiLastldstirLwdyekekvvktYkghknekycisaefsetggklvvsGsedgkvyiwdlqskeivqkle 259 p n + ++++ st+ ++++ ++++v++++ k + +++ ++ +g++v + ed +y +++ + ++ q+l+ FUN_001771-T1 407 PrNPEQFVVCNRTSTVLVMNM-QGQIVRSFTSGKRDGGDFVCCTLSPRGEWVYCVGEDMVMYCFSTMTGKLEQSLQ 481 95667888999999*999999.599*****9777665555555555699*********************999986 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 2.7e-07 0.00012 222 265 .. 214 257 .. 197 264 .. 0.80 2 ! 25.0 0.0 2.9e-08 1.3e-05 126 167 .. 262 303 .. 255 309 .. 0.84 3 ! 71.7 0.1 1.8e-22 7.7e-20 89 256 .. 310 476 .. 306 483 .. 0.88 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 2.7e-07 WD40_WDHD1_1st 222 sedisivafSpcGkylaaatvdgeilvWdvatkeliervkhekk 265 ++ +v+fSp+G+yl++++vdg i v++++t ++ + +k++ + FUN_001771-T1 214 KSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAQ 257 44456999999999999999999999999999999888887765 PP == domain 2 score: 25.0 bits; conditional E-value: 2.9e-08 WD40_WDHD1_1st 126 ghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlk 167 +++vl++a++ +e+laS + DG++k+W++++++c++ ++ FUN_001771-T1 262 MMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFE 303 567899****************************99998775 PP == domain 3 score: 71.7 bits; conditional E-value: 1.8e-22 WD40_WDHD1_1st 89 vthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlpksndfsaskslcr 183 +t++++s+d + l +gs D+ti++ ++ +++ k+++gh++ v + ++ ++S+s+DG+vk+W+++++ec++t+k p + ++ + +++ FUN_001771-T1 310 ITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFK--PAVGSVATDITVNS 402 8**************************************************************************9966..68999999999999 PP WD40_WDHD1_1st 184 lawepksgkllavPvek.evklyerdtweeafklsknkls.edisivafSpcGkylaaatvdgeilvWdvatkel 256 ++ p++ + + v ++ +v +++ + + + ++++ k + d+ +++ Sp G+++ ++d ++++++ t +l FUN_001771-T1 403 VHLMPRNPEQFVVCNRTsTVLVMNMQ-GQIVRSFTSGKRDgGDFVCCTLSPRGEWVYCVGEDMVMYCFSTMTGKL 476 9999*999999999777256666665.5556666655555489*************************9988776 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.0 9.2e-08 4e-05 14 39 .] 217 242 .. 205 242 .. 0.86 2 ! 28.4 0.0 5e-09 2.2e-06 12 38 .. 265 291 .. 261 292 .. 0.94 3 ! 28.6 0.0 4.4e-09 1.9e-06 1 37 [. 296 333 .. 296 334 .. 0.92 4 ! 29.4 0.1 2.6e-09 1.1e-06 1 39 [] 339 377 .. 339 377 .. 0.95 5 ? 7.0 0.1 0.032 14 14 37 .. 446 468 .. 429 470 .. 0.74 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 9.2e-08 WD40 14 VtslafspdgsllasgsdDgtvklWd 39 +++fspdg++l++gs Dg + +++ FUN_001771-T1 217 PECVKFSPDGQYLVTGSVDGFIEVYN 242 56********************9986 PP == domain 2 score: 28.4 bits; conditional E-value: 5e-09 WD40 12 sgVtslafspdgsllasgsdDgtvklW 38 ++V +lafs d+ +lasg+ Dg++k+W FUN_001771-T1 265 DSVLCLAFSRDSEMLASGGQDGKLKVW 291 57************************* PP == domain 3 score: 28.6 bits; conditional E-value: 4.4e-09 WD40 1 gkllrtl.kgHtsgVtslafspdgsllasgsdDgtvkl 37 g++lr + k+H +g+t+++fs d s l+sgs D t+++ FUN_001771-T1 296 GQCLRRFeKAHAKGITCVTFSRDASQLLSGSFDMTIRM 333 689999967**999**********************97 PP == domain 4 score: 29.4 bits; conditional E-value: 2.6e-09 WD40 1 gkllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 gk l++++gHts V++ f d + ++s+s Dg+vklW+ FUN_001771-T1 339 GKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWN 377 67899*****999****************99*******7 PP == domain 5 score: 7.0 bits; conditional E-value: 0.032 WD40 14 VtslafspdgsllasgsdDgtvkl 37 V +++ sp g ++++ ++D ++ FUN_001771-T1 446 V-CCTLSPRGEWVYCVGEDMVMYC 468 6.999*********9999987665 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 6.7e-05 0.03 27 65 .. 212 250 .. 200 256 .. 0.74 2 ! 100.1 1.0 3.7e-31 1.6e-28 28 158 .. 263 394 .. 250 406 .. 0.92 3 ? 0.9 0.0 1 4.6e+02 2 68 .. 413 481 .. 412 495 .. 0.73 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 6.7e-05 Beta-prop_WDR3_1st 27 geksevtalaaspdgkklavGyadgsirlwdlesgelev 65 g+ks+ +++++spdg+ l +G+ dg i+++++++g+++ FUN_001771-T1 212 GTKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRK 250 566777788888888888888888888888888887664 PP == domain 2 score: 100.1 bits; conditional E-value: 3.7e-31 Beta-prop_WDR3_1st 28 eksevtalaaspdgkklavGyadgsirlwdlesgelevtfn.gHksavtalafdkdgsrLasGskDtdiivwDvvaeaglfrLkgHkdqvt 117 +++v +la+s+d+++la+G +dg++++w++++g++ f+ +H + +t+++f++d s+L sGs D +i + + +++ l ++gH++ v+ FUN_001771-T1 263 MDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEkAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVN 353 46789**********************************9548************************************************ PP Beta-prop_WDR3_1st 118 svafleekkvlvssSkDtliklWdletqhcvktlvghrsev 158 ++ f + + ++s+S+D +klW+++t +c++t+ + v FUN_001771-T1 354 DAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSV 394 *********************************98776666 PP == domain 3 score: 0.9 bits; conditional E-value: 1 Beta-prop_WDR3_1st 2 lvavgalekvlvWdlkkgekvatl.egek..sevtalaaspdgkklavGyadgsirlwdlesgelevtfn 68 +v++ + +vlv +++ + v+++ +g++ + + + sp+g+ + + +d +++ +g+le++++ FUN_001771-T1 413 FVVCNRTSTVLVMNMQGQ-IVRSFtSGKRdgGDFVCCTLSPRGEWVYCVGEDMVMYCFSTMTGKLEQSLQ 481 577777888899888654.455541444322678899999999999888899********9999998875 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.3 0.0 1.2e-16 5.4e-14 173 252 .. 216 303 .. 200 308 .. 0.76 2 ! 55.2 0.2 1.7e-17 7.4e-15 1 87 [. 306 389 .. 306 406 .. 0.91 Alignments for each domain: == domain 1 score: 52.3 bits; conditional E-value: 1.2e-16 Beta-prop_THOC3 173 nclcvafdpkgrylAvGsaDalvslWDleeliclrtlt........rlespvrsvsFShdGkllAsasedktidiasvetgesvhtik 252 + cv+f+p+g+yl++Gs D ++++++++++ + l+ ++ +v +++FS d+++lAs+++d ++++++v+tg+++ +++ FUN_001771-T1 216 HPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKyqaqdnfmMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFE 303 4458999999999999999999999998888776655544444444788899999999999999999999999999999999888775 PP == domain 2 score: 55.2 bits; conditional E-value: 1.7e-17 Beta-prop_THOC3 1 hkkkvhsvawsadGkrLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvkt 87 h k +++v +s d ++L sgs D t+r+ l+++k k e++ght+ V+ + + + +++assD +v+lW+v+t+++++t+k FUN_001771-T1 306 HAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLK--EFRGHTSFVNDAIFTMDA-HNIISASSDGSVKLWNVKTTECLHTFKP 389 8899*****************************99887..7*************9876.679*********************9875 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.4 0.4 4.2e-22 1.9e-19 8 205 .. 215 424 .. 208 429 .. 0.82 2 ! 55.9 0.4 1e-17 4.5e-15 6 207 .. 263 470 .. 261 481 .. 0.78 Alignments for each domain: == domain 1 score: 70.4 bits; conditional E-value: 4.2e-22 WDR55 8 dlvvdisfhPsediiavgtidGdvllykysneenen....kellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespi 99 ++ ++f+P+ + +++g++dG + +y++++ + ++ + ++ + ++s+ +++Fs+d + l s +D +++v v+tg++++++ekah + i FUN_001771-T1 215 SHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKdlkyQAQDNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKAHAKGI 310 5566799**********************997654311113445667899********************************************** PP WDR55 100 ysllvi.denllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfnirkkk......levqseeyeeellslalv 188 +++ d l +G d t+++ l + k++ e++ h +++d +++ + + ++++s dG+++ +n+++ + v s + ++s+ l+ FUN_001771-T1 311 TCVTFSrDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTEclhtfkPAVGSVATDITVNSVHLM 406 ***986366799********************************************************9987322222356677777788888888 PP WDR55 189 kee.kkvvvGsseGklyl 205 ++ ++ vv++ + ++ + FUN_001771-T1 407 PRNpEQFVVCNRTSTVLV 424 544255666666555555 PP == domain 2 score: 55.9 bits; conditional E-value: 1e-17 WDR55 6 ledlvvdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiys 101 ++d v+ ++f+ +++++a g dG+ +++k ++ ++ ++h k + +v+Fs+d ++l+s s D +i+++ +++gk++k+++ + + FUN_001771-T1 263 MDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQC---LRRFEKAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDA 355 678899999999999999999999999999998554...233347899999999999999999999999999999999999999998655555558 PP WDR55 102 llvidenllatGdddGtvklWDlRkkkavmelkehedyi.sdlvvde......ekklLlatsgdGtltvfnirkkklev.qse.eyeeellslalv 188 + ++d + ++++ dG vklW + + ++++++k + +d++v++ + + +++ t+ v+n++ + + +s ++++++l FUN_001771-T1 356 IFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSVaTDITVNSvhlmprNPEQFVVCNRTSTVLVMNMQGQIVRSfTSGkRDGGDFVCCTLS 451 889999999999999999999999999999999765554267777653333334455666666688888898888654313431445799999999 PP WDR55 189 keekkvvvGsseGklylfn 207 +++ v + ++ ++y f+ FUN_001771-T1 452 PRGEWVYCVGEDMVMYCFS 470 9999999999999999987 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.2 0.0 1.4e-15 6.3e-13 80 158 .. 213 298 .. 186 303 .. 0.86 2 ! 55.3 0.3 2e-17 8.7e-15 27 157 .. 252 382 .. 248 388 .. 0.93 3 ! 17.8 0.1 5.2e-06 0.0023 11 112 .. 362 473 .. 358 491 .. 0.74 Alignments for each domain: == domain 1 score: 49.2 bits; conditional E-value: 1.4e-15 Beta-prop_EML_2 80 rkeaisdikfspdgklLavgshdnkiylYdvsk.......kykkvgklkghssfithlDwsedskylqsnsgdyellfwdaktgkq 158 +k++ +++kfspdg++L+ gs d++i++Y+++ ky+ ++ +++ +++l +s ds++l s +d++l +w+++tg+ FUN_001771-T1 213 TKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTgkirkdlKYQAQDNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQC 298 678999************************986555556679999**************************************986 PP == domain 2 score: 55.3 bits; conditional E-value: 2e-17 Beta-prop_EML_2 27 lekkklvakvklekearsvafspdgkllavGlkdGsvlvldaetleevvevkd.rkeaisdikfspdgklLavgshdnkiylYdvskkykkvgk 119 l+ +++ + + +++++ ++afs d ++la G +dG++ v++ +t++ + ++++ + + i++++fs d + L gs d +i ++ + k+ k +++ FUN_001771-T1 252 LKYQAQDNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKaHAKGITCVTFSRDASQLLSGSFDMTIRMHGL-KSGKTLKE 344 666778888999************************************998663789***************************7.77999*** PP Beta-prop_EML_2 120 lkghssfithlDwsedskylqsnsgdyellfwdaktgk 157 ++gh+sf+ ++ d + + s s+d+++ +w++kt++ FUN_001771-T1 345 FRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTE 382 **********************************9987 PP == domain 3 score: 17.8 bits; conditional E-value: 5.2e-06 Beta-prop_EML_2 11 pqfvTagdDktvrlWdlekkkl.......vakvklekearsvafspdg.kllavGlkdGsvlvldaet..leevvevkdrkeaisdikfspdgk 94 + +++a+ D++v lW++++ ++ v +v ++ +++sv++ p++ ++++v + +vlv++ + +++ ++ k + +++ sp g+ FUN_001771-T1 362 HNIISASSDGSVKLWNVKTTEClhtfkpaVGSVATDITVNSVHLMPRNpEQFVVCNRTSTVLVMNMQGqiVRSFTSGKRDGGDFVCCTLSPRGE 455 67899**************988333333344556667899999998772567777777777777654311334445566778999********* PP Beta-prop_EML_2 95 lLavgshdnkiylYdvsk 112 ++ + +d ++y +++ FUN_001771-T1 456 WVYCVGEDMVMYCFSTMT 473 ****99*******99754 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 0.0 1.4e-12 6.1e-10 135 216 .. 214 303 .. 192 307 .. 0.81 2 ! 60.1 0.1 5.6e-19 2.5e-16 3 158 .. 304 465 .. 302 491 .. 0.76 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 1.4e-12 WD40_Prp19 135 keaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghs........gavtslaFSeNGYyLAsasedgtvklWDLRklknfktle 216 k++ ++++f PDG+ l tG+ dg++++++ ++k+ ++l+ ++ ++v +laFS + +LAs+ +dg+ k+W ++++ +e FUN_001771-T1 214 KSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAqdnfmmmdDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFE 303 456689****************************9999953322233444478*************************999999888776 PP == domain 2 score: 60.1 bits; conditional E-value: 5.6e-19 WD40_Prp19 3 sstkpgilaldlnpsdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkk......hka 92 +++++gi++++++ +d +++l+G D ++ ++ +s+k+l++++ght v+++ f ++++++sas+D++v++w+ + +e+ +t+k + FUN_001771-T1 304 KAHAKGITCVTFS-RDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPavgsvaTDI 398 67899*******9.5789******************************************************************997333322334 PP WD40_Prp19 93 evtslsvhptg.dylvsaskDgtwalhdletgktllkvkd.eeskeaitsaqfHPDGlllgtGtkdgt 158 +v+s+ + p + + +v + + +t+ + ++ +g++++++++ ++++ ++ + + P G + + +d + FUN_001771-T1 399 TVNSVHLMPRNpEQFVVCNRTSTVLVMNM-QGQIVRSFTSgKRDGGDFVCCTLSPRGEWVYCVGEDMV 465 67888888887345555555555555554.57777776551444667888888888876655555555 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 81.8 0.8 1.8e-25 7.7e-23 112 288 .. 214 399 .. 202 409 .. 0.85 2 ? 1.9 0.0 0.34 1.5e+02 231 276 .. 430 478 .. 402 490 .. 0.60 Alignments for each domain: == domain 1 score: 81.8 bits; conditional E-value: 1.8e-25 Beta-prop_WDR36-Utp21_2nd 112 kvvataveissCGnfvviGyssGhvdrfNlqSglhRgsyg...keka...hkkavrGvavdalnqvvitagadkklkfwkfksk 189 k + ++v+ s G + v G+ +G ++++N g R+ + ++ +++v +a + ++++ ++g+d+klk+wk+++ FUN_001771-T1 214 KSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKyqaQD-NfmmMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTG 296 66789********************************87422222.23337889****************************** PP Beta-prop_WDR36-Utp21_2nd 190 klletlk..leasisklvlhressllavalddfsilvvDidtrrvvRkfsghknritDltfspdarWlitasmDstirtwdlps 271 + l+ ++ + i+ +++ r++s l d++i++ +++ ++ ++f+gh++ ++D++f da+ +i+as+D +++ w++++ FUN_001771-T1 297 QCLRRFEkaHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKT 380 *99987633567899999999987666666789*************************************************** PP Beta-prop_WDR36-Utp21_2nd 272 gkliDvfl..vesaatsls 288 ++ + +f+ v s+at ++ FUN_001771-T1 381 TECLHTFKpaVGSVATDIT 399 ******9855556655555 PP == domain 2 score: 1.9 bits; conditional E-value: 0.34 Beta-prop_WDR36-Utp21_2nd 231 rvvRkfsghknritD...ltfspdarWlitasmDstirtwdlpsgkliD 276 ++vR+f+ k D t+sp + W+ + D + ++ +gkl FUN_001771-T1 430 QIVRSFTSGKRDGGDfvcCTLSPRGEWVYCVGEDMVMYCFSTMTGKLEQ 478 5677776554433331115667777777777777777666666666544 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.007 3.1 85 113 .. 209 237 .. 183 250 .. 0.79 2 ! 65.1 1.1 1.7e-20 7.6e-18 91 209 .. 265 383 .. 248 400 .. 0.90 3 ! 23.1 0.3 1.1e-07 5.1e-05 13 120 .. 365 472 .. 364 486 .. 0.87 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.007 Beta-prop_TEP1_2nd 85 vlrghtgavtccsfsldGgllatggrdrs 113 + g ++ c fs+dG++l tg+ d FUN_001771-T1 209 IKFGTKSHPECVKFSPDGQYLVTGSVDGF 237 4557778889***************9965 PP == domain 2 score: 65.1 bits; conditional E-value: 1.7e-20 Beta-prop_TEP1_2nd 91 gavtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkdd.llvscssdGsvglWdiekeqrlgkflGhqsav 180 +v c +fs d ++la+gg+d +l +W v++ +r + h +t+ ++ +d+ l+s+s d ++++ +++++ l++f Gh s v FUN_001771-T1 265 DSVLCLAFSRDSEMLASGGQDGKLKVWKVQT---GQCLRRFEKAHAKGITCVTFSRDAsQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFV 352 6899*************************99...456899**************9985379****************************** PP Beta-prop_TEP1_2nd 181 s.avvaveeh.vvsvgrdGllkvWdlqGvel 209 a+ ++++h ++s + dG++k W+ + +e FUN_001771-T1 353 NdAIFTMDAHnIISASSDGSVKLWNVKTTEC 383 7578999987699************999885 PP == domain 3 score: 23.1 bits; conditional E-value: 1.1e-07 Beta-prop_TEP1_2nd 13 vsGaedgslqvWkleesssqcllllkahqkavlg..lalsqkllasasedltvrlWskelltqpekaeslsslsvlrghtgavtccsfsld 101 +s ++dgs++ W++++ ++cl+++k ++v + s +l+ e++ v+ ++ l+++ + + ++s + + g cc++s+ FUN_001771-T1 365 ISASSDGSVKLWNVKT--TECLHTFKPAVGSVATdiTVNSVHLMPRNPEQFVVCNRTSTVLVMNMQGQIVRSFTSGKRDGGDFVCCTLSPR 453 7899*********975..6799999988888876223458899********************99999999999999999*********** PP Beta-prop_TEP1_2nd 102 GgllatggrdrsllcWdvr 120 G+ + g d ++c+ FUN_001771-T1 454 GEWVYCVGEDMVMYCFSTM 472 ***************9765 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.9 0.0 3.3e-11 1.5e-08 154 262 .. 218 333 .. 203 336 .. 0.86 2 ! 40.4 0.1 7e-13 3.1e-10 130 249 .. 286 410 .. 286 416 .. 0.90 3 ! 20.3 0.2 9.3e-07 0.00041 122 151 .. 363 396 .. 337 439 .. 0.74 4 ? -0.5 0.0 2.1 9.3e+02 47 104 .. 421 483 .. 409 497 .. 0.63 Alignments for each domain: == domain 1 score: 34.9 bits; conditional E-value: 3.3e-11 Beta-prop_WDR36-Utp21_1st 154 taleqspaldvvaiglasGeivlhnikkdetllklkqeegp........vtsisFrtDgepvlatgsssGdialwdLekrrlvh 229 +++ sp + + g +G i ++n ++++ +lk +++ v +++F D +++la+g ++G++ +w ++++ + FUN_001771-T1 218 ECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAQDnfmmmddsVLCLAFSRD-SEMLASGGQDGKLKVWKVQTGQCLR 300 68888999999999***************99999985422223444444********9.67*********************** PP Beta-prop_WDR36-Utp21_1st 230 vlrnaHeggvtkleflpgqpllvtsgaDNslke 262 ++aH++g+t+++f + l++ + D ++++ FUN_001771-T1 301 RFEKAHAKGITCVTFSRDASQLLSGSFDMTIRM 333 *************************99988876 PP == domain 2 score: 40.4 bits; conditional E-value: 7e-13 Beta-prop_WDR36-Utp21_1st 130 GslqlwNirtgkliytfksf.ksaitaleqspaldvvaiglasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgs 212 G+l++w ++tg+++ +f++ ++ it+++ s + + g + +i +h +k ++tl +++ +++ v+ F D ++ ++++s FUN_001771-T1 286 GKLKVWKVQTGQCLRRFEKAhAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHN-IISAS 368 89***************8772699***************************************9***********776.57999 PP Beta-prop_WDR36-Utp21_1st 213 ssGdialwdLekrrlvhvlrnaHeg.....gvtkleflpgqp 249 s+G++ lw+ ++ + +h+ + a + +v++++ +p++p FUN_001771-T1 369 SDGSVKLWNVKTTECLHTFKPAVGSvatdiTVNSVHLMPRNP 410 9*****************999877666777778887777765 PP == domain 3 score: 20.3 bits; conditional E-value: 9.3e-07 Beta-prop_WDR36-Utp21_1st 122 KilvgskqGslqlwNirtgkliytfksfk....s 151 i+ +s++Gs++lwN++t ++++tfk+ + FUN_001771-T1 363 NIISASSDGSVKLWNVKTTECLHTFKPAVgsvaT 396 58889********************966523332 PP == domain 4 score: -0.5 bits; conditional E-value: 2.1 Beta-prop_WDR36-Utp21_1st 47 kivvfkrgkevaellkeheek.....ikkllvfgdhlvavdednsllvwkieteelyteiefs 104 ++ v++ ++++ +++ +++ +l + g+++ +v ed ++++++ t++l +++++ FUN_001771-T1 421 TVLVMNMQGQIVRSFTSGKRDggdfvCCTLSPRGEWVYCVGEDMVMYCFSTMTGKLEQSLQVG 483 555555555555554222222122325677888999999999999999999999888888765 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.8 0.3 1.7e-22 7.7e-20 50 287 .. 213 464 .. 190 469 .. 0.82 Alignments for each domain: == domain 1 score: 71.8 bits; conditional E-value: 1.7e-22 WD40_CDC20-Fz 50 esdyvtsvkwsedgelLavGtssgevelwdvekkkklrtleghs........srvgalaw..nenllssGsrdgkilhhDvrtkelevvktlkahk 135 ++++ +vk+s+dg++L++G+ +g +e+++ +++k+ ++l+ ++ ++v +la+ ++++l+sG +dgk+ ++ v+t + + kah FUN_001771-T1 213 TKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAqdnfmmmdDSVLCLAFsrDSEMLASGGQDGKLKVWKVQTGQCL-RRFEKAHA 307 357889*****************************9998876543456666678****99544567******************864.455689** PP WD40_CDC20-Fz 136 qevcglkwspdgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslLatGGGtaDktirlwntntgkl.......lksvdtgsqv 224 + ++ +++s+d ++l sG+ d t+++ l+s + l++++ h++ v + ++++ ++D++++lwn++t ++ + sv t+ v FUN_001771-T1 308 KGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIIS---ASSDGSVKLWNVKTTEClhtfkpaVGSVATDITV 400 **********************************************999***9999995...467**********999722222224567899999 PP WD40_CDC20-Fz 225 tsllwskee.kelvsthgysknqivlwkypslkkvaeleghtervlslalspdgetvvtasaDe 287 s++ +++ +++v++ s+ ++ + + ++ ++ + + + +lsp+ge v +++D FUN_001771-T1 401 NSVHLMPRNpEQFVVCNRTSTVLVMNMQGQIVRSFTSGKRDGGDFVCCTLSPRGEWVYCVGEDM 464 9999988653788888888776666666666777777777888999999999999999888885 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.2 1.4 8.1e-24 3.6e-21 84 263 .. 218 395 .. 203 417 .. 0.90 Alignments for each domain: == domain 1 score: 76.2 bits; conditional E-value: 8.1e-24 Beta-prop_WDR3_2nd 84 wsvaltpdekglvtggaDkkvkfwefelveeeeskakklslkh.trtlklsddvlcvkvspdkkllavallDstvkvfflDtlkfflsl.Y 172 +v+ +pd+++lvtg+ D +++++f++ + +k l+ ++ + ++d vlc+ +s d+++la D + kv+ + t + + FUN_001771-T1 218 ECVKFSPDGQYLVTGSVDGFIEVYNFTTGKI----RKDLKYQAqDNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFeK 304 578999********************98775....566766550566789999*****************************999888834 PP Beta-prop_WDR3_2nd 173 GhklPvlsldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkvkyWDadkfekiqtleghagevw 263 h ++++ +s D++ +++gs D +i+++Gl G k + +h++ v + f+ +H+++sa+ d++vk W+ + e++ t++ g v FUN_001771-T1 305 AHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSVA 395 7999******************************************************************************999998875 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.3 0.0 0.0017 0.76 290 315 .. 219 244 .. 211 255 .. 0.87 2 ! 17.7 0.0 5e-06 0.0022 53 92 .. 265 304 .. 258 308 .. 0.90 3 ! 38.5 0.1 2.3e-12 1e-09 8 104 .. 305 399 .. 302 481 .. 0.81 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0017 EIF3I 290 tlavhPdGksyasggEdGyvrvhefd 315 +++++PdG+ +++g+ dG++ v +f FUN_001771-T1 219 CVKFSPDGQYLVTGSVDGFIEVYNFT 244 79999**************9999996 PP == domain 2 score: 17.7 bits; conditional E-value: 5e-06 EIF3I 53 GavwsidvdsettllvtgsadntvklWdvetGkelktlet 92 +v ++ + ++++l++g d ++k+W+v+tG++l+++e FUN_001771-T1 265 DSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEK 304 579999*****************************99876 PP == domain 3 score: 38.5 bits; conditional E-value: 2.3e-12 EIF3I 8 GheRaltqikynreGDllfsvakdkkasvwysenGerlGtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktletktavrsvefse 103 h + +t + ++r+ l+s + d ++ ++ + G l ++Gh+ v + ++++++++++s+d +vklW+v+t ++l+t++ av sv+ + FUN_001771-T1 305 AHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKP--AVGSVATDI 398 6999****************************************************************************99764..344444333 PP EIF3I 104 s 104 + FUN_001771-T1 399 T 399 3 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 0.0 1.3e-11 5.6e-09 83 204 .. 209 333 .. 184 336 .. 0.77 2 ! 22.5 0.1 1.5e-07 6.8e-05 290 340 .. 327 377 .. 323 378 .. 0.94 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 1.3e-11 WD40_MABP1-WDR62_2nd 83 seldsknGvRvlkvspdgkhlasGDrsGniriydlet..leellkieah......dsevlcleyskpetglkllasasRDRlihvfdve 163 ++ +k+ ++k+spdg+ l +G G i +y+++t +++ lk +a d vlcl +s+ ++las++ D ++v++v+ FUN_001771-T1 209 IKFGTKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTgkIRKDLKYQAQdnfmmmDDSVLCLAFSRD---SEMLASGGQDGKLKVWKVQ 294 45566667789**********************9975224444454544111111679******985...589**************** PP WD40_MABP1-WDR62_2nd 164 kdysllqtlddhsssitavkfaeeeeklkliscgaDksilf 204 + l + + h+ it+v f+++ +l+s + D +i + FUN_001771-T1 295 TGQCLRRFEKAHAKGITCVTFSRDA--SQLLSGSFDMTIRM 333 ***999999************9865..57899999988866 PP == domain 2 score: 22.5 bits; conditional E-value: 1.5e-07 WD40_MABP1-WDR62_2nd 290 sdknlsildfesGecvatvfGhseivtglkFtedcrhlisvsgDsCifvWr 340 d ++ + ++sG+++ Gh+ v + Ft d++++is+s+D+ + +W+ FUN_001771-T1 327 FDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWN 377 5889999*******************************************7 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 3.9e-05 0.017 42 82 .. 218 258 .. 207 264 .. 0.87 2 ! 24.3 0.0 8.5e-08 3.7e-05 38 89 .. 264 316 .. 260 318 .. 0.91 3 ? 6.5 0.0 0.03 13 35 80 .. 304 349 .. 302 360 .. 0.88 4 ! 13.0 0.0 0.0003 0.13 37 81 .. 348 392 .. 326 406 .. 0.83 5 ? -1.0 0.0 6.9 3e+03 54 82 .. 413 441 .. 391 461 .. 0.68 6 ? -1.4 0.0 9.1 4e+03 16 82 .. 419 441 .. 413 483 .. 0.49 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 3.9e-05 ANAPC4_WD40 42 tslaWkpdGklLavaysdgevrlldvesgklvhslsaksdk 82 ++++++pdG+ L+ + dg +++++ +gk+ + l++++++ FUN_001771-T1 218 ECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAQD 258 6899******************************9998775 PP == domain 2 score: 24.3 bits; conditional E-value: 8.5e-08 ANAPC4_WD40 38 dsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdk.itcleWa 89 d +v +la++ d ++La + +dg++++ +v++g++++ ++ ++ k itc++++ FUN_001771-T1 264 DDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKAHAKgITCVTFS 316 67899**********************************8777767****997 PP == domain 3 score: 6.5 bits; conditional E-value: 0.03 ANAPC4_WD40 35 ekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaks 80 +++ + +t++ ++ d L + d ++r++ +sgk++++++ ++ FUN_001771-T1 304 KAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHT 349 5677889*********************************998765 PP == domain 4 score: 13.0 bits; conditional E-value: 0.0003 ANAPC4_WD40 37 edsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksd 81 ++s v++ + +d + ++ a sdg+v+l +v++++++h+++ + FUN_001771-T1 348 HTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVG 392 666788888999***************************987655 PP == domain 5 score: -1.0 bits; conditional E-value: 6.9 ANAPC4_WD40 54 avaysdgevrlldvesgklvhslsaksdk 82 v+++ ++ l+ +g++v+s+++++ + FUN_001771-T1 413 FVVCNRTSTVLVMNMQGQIVRSFTSGKRD 441 46666666667777788888888877665 PP == domain 6 score: -1.4 bits; conditional E-value: 9.1 ANAPC4_WD40 16 dgevllkRlnwqrvwklseekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdk 82 ++ vl+ +++q v +s+++++ + FUN_001771-T1 419 TSTVLVMNMQGQIV--------------------------------------------RSFTSGKRD 441 34444444444444............................................444444332 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.9 0.2 2.1e-10 9.4e-08 144 259 .. 215 340 .. 200 343 .. 0.80 2 ! 33.5 0.5 7.2e-11 3.2e-08 141 225 .. 305 390 .. 301 430 .. 0.81 3 ? 0.8 0.1 0.6 2.6e+02 101 128 .. 446 471 .. 438 483 .. 0.78 Alignments for each domain: == domain 1 score: 31.9 bits; conditional E-value: 2.1e-10 WD40_Gbeta 144 gylsccrflddnq.ivtssgdttcalwdietg........qqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtf.ighesdi 229 + c++f d q +vt s d +++ tg q + f+ v+ l+++ d++++ sg d k+w v+ g c + f h i FUN_001771-T1 215 SHPECVKFSPDGQyLVTGSVDGFIEVYNFTTGkirkdlkyQAQDNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFeKAHAKGI 310 455799998776637999*********9999933322222234456667777999*****************************8888357999** PP WD40_Gbeta 230 naiaffpngealatgsddatcrlfdlradq 259 +++f + + l +gs d t r+ l++ + FUN_001771-T1 311 TCVTFSRDASQLLSGSFDMTIRMHGLKSGK 340 ***********************9998765 PP == domain 2 score: 33.5 bits; conditional E-value: 7.2e-11 WD40_Gbeta 141 ghtgylsccrfldd.nqivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfigh 225 +h+ ++c+ f d q+++ s d t + +++g+ f ght v ++ d++ ++s + d s+klw+v+ + c +tf FUN_001771-T1 305 AHAKGITCVTFSRDaSQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPA 390 7888899**997552789999*************************************************************9633 PP == domain 3 score: 0.8 bits; conditional E-value: 0.6 WD40_Gbeta 101 mtcayapsgnfvacggldnicsiynlkt 128 + c+ +p g++v c g d + ++ t FUN_001771-T1 446 VCCTLSPRGEWVYCVGEDMVMYCFS--T 471 5799************998765544..3 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 5.1e-07 0.00022 74 168 .. 218 302 .. 191 310 .. 0.79 2 ! 37.5 0.1 4.3e-12 1.9e-09 68 212 .. 262 389 .. 249 406 .. 0.87 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 5.1e-07 Beta-prop_CAF1B_HIR1 74 nvvrfspsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlswspdskklisgsvDntailWdvekg 162 +v+fsp+g++L +g+ ++ i +++ ++ + + ++ + + +++++++ + v l++s+ds++l sg D + +W+v+ g FUN_001771-T1 218 ECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIR----KDLKYQAQDNFMMM------DDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTG 296 6999*****************99999998643....34456677777765......478999***********************9999 PP Beta-prop_CAF1B_HIR1 163 kklail 168 + l + FUN_001771-T1 297 QCLRRF 302 977655 PP == domain 2 score: 37.5 bits; conditional E-value: 4.3e-12 Beta-prop_CAF1B_HIR1 68 rhqkavnvvrfspsgelLasgdDesviiiWklkeeeeeinlleeeeeenketwlvlkvlrGhledvyDlswspdskklisgsvDntail 156 +v + fs + e+Lasg+ ++++ +Wk ++ + + + + h + + +++s+d+++l+sgs D t+ + FUN_001771-T1 262 MMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQC-LR----------------RFEKAHAKGITCVTFSRDASQLLSGSFDMTIRM 333 556789999***********************99963.23................344689999************************ PP Beta-prop_CAF1B_HIR1 157 WdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkvvarvsk 212 ++ gk+l+ ++ h +fv + + ++++ssD s++++++kt+++++ + FUN_001771-T1 334 HGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKP 389 *************************99**********************9997765 PP >> LisH_TPL LisH-like dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.6 0.0 3.4e-16 1.5e-13 1 30 [. 6 35 .. 6 36 .. 0.97 Alignments for each domain: == domain 1 score: 50.6 bits; conditional E-value: 3.4e-16 LisH_TPL 1 eSsDvVRLIlQFLkEekLhetlqaLqqESg 30 eS+Dv+RL++QFLkE++L +tl++Lq+E+g FUN_001771-T1 6 ESADVIRLVQQFLKENSLPRTLATLQEETG 35 8****************************9 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 5e-06 0.0022 36 107 .. 214 293 .. 206 295 .. 0.82 2 ! 23.5 0.0 8.6e-08 3.8e-05 202 283 .. 287 367 .. 283 369 .. 0.83 3 ! 11.3 0.1 0.00047 0.2 11 108 .. 366 472 .. 364 494 .. 0.72 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 5e-06 Beta-prop_WDR90_POC16_2nd 36 eeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkq........hrgkvtglvfspdgeylysacslGslalyda 107 + P +v f P q ++ G+ +G + v++ ++ ++ + k +v l+fs+d+e+l s ++ G+l ++++ FUN_001771-T1 214 KSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYqaqdnfmmMDDSVLCLAFSRDSEMLASGGQDGKLKVWKV 293 678****************************99998776641111111145789*********************99886 PP == domain 2 score: 23.5 bits; conditional E-value: 8.6e-08 Beta-prop_WDR90_POC16_2nd 202 kllkldaktGrllrevsevhrsacsslavsedarylltag.dkvikvwdysmkldinfqvfiGhsekvqqvaftpdqqevlsv 283 kl + + +tG+ lr+ ++ h +++++++ s+da+ ll+++ d +i++ + +k + f Gh+ v+ ft d ++++s+ FUN_001771-T1 287 KLKVWKVQTGQCLRRFEKAHAKGITCVTFSRDASQLLSGSfDMTIRM--HGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISA 367 666778899**********************9999987653555555..5677788889999****************99997 PP == domain 3 score: 11.3 bits; conditional E-value: 0.00047 Beta-prop_WDR90_POC16_2nd 11 tvseDetiriWdldtlqqlydfs......aseeaPcavafhPsk.qvfacGfssGvvrvfsveat..sllaehkqhrgkvtglv 85 +s+D ++++W+++t++ l+ f+ a++ + +v+ P + + f+ ++ +v v++++ + + k+ g + + FUN_001771-T1 366 SASSDGSVKLWNVKTTECLHTFKpavgsvATDITVNSVHLMPRNpEQFVVCNRTSTVLVMNMQGQivRSFTSGKRDGGDFVCCT 449 689*******************8322222334455678888986324544556667778887754115577888899******* PP Beta-prop_WDR90_POC16_2nd 86 fspdgeylysacslGslalydas 108 +sp ge++y ++ ++ +++ FUN_001771-T1 450 LSPRGEWVYCVGEDMVMYCFSTM 472 *********98877665555544 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 1.1e-06 0.00047 156 221 .. 214 287 .. 197 288 .. 0.81 2 ! 32.3 0.1 2.3e-10 9.9e-08 156 223 .. 264 332 .. 249 346 .. 0.84 3 ? 6.1 0.2 0.022 9.8 149 196 .. 342 390 .. 329 441 .. 0.70 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 1.1e-06 Beta-prop_EML 156 pkyvlclafsengd.vitGdsnGnilvWskgtnkiskavk.......kahegsvfsllvlkdgtllsgggkdgk 221 +++ c++fs++g+ ++tG +G i v++ +t ki k +k + + sv++l +++d+ +l +gg+dgk FUN_001771-T1 214 KSHPECVKFSPDGQyLVTGSVDGFIEVYNFTTGKIRKDLKyqaqdnfMMMDDSVLCLAFSRDSEMLASGGQDGK 287 55668*********889************88888877665433332246789********************98 PP == domain 2 score: 32.3 bits; conditional E-value: 2.3e-10 Beta-prop_EML 156 pkyvlclafsengd.vitGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkiv 223 + vlclafs++ + + +G ++G++ vW+ +t ++ + +kah ++++++++++d + l +g d +i FUN_001771-T1 264 DDSVLCLAFSRDSEmLASGGQDGKLKVWKVQTGQCLRRFEKAHAKGITCVTFSRDASQLLSGSFDMTIR 332 5689******9988467**************************************88887778887765 PP == domain 3 score: 6.1 bits; conditional E-value: 0.022 Beta-prop_EML 149 ifeksekpkyvlclafsengd.vitGdsnGnilvWskgtnkiskavkka 196 + e + + ++v + f+ + + +i++ s+G++ +W+ +t+++ ++ k a FUN_001771-T1 342 LKEFRGHTSFVNDAIFTMDAHnIISASSDGSVKLWNVKTTECLHTFKPA 390 5555556667777777766443999999999999999999888887743 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.0 0.012 5.4 57 90 .. 221 254 .. 203 261 .. 0.84 2 ! 39.7 1.2 1.2e-12 5.2e-10 57 255 .. 271 483 .. 260 497 .. 0.84 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.012 Beta-prop_ACSF4 57 cvskdgklvvvGcydgklycldlatgeilwkfkt 90 +s+dg+++v G+ dg++ +++++tg+i k FUN_001771-T1 221 KFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKY 254 4588999*******************99987665 PP == domain 2 score: 39.7 bits; conditional E-value: 1.2e-12 Beta-prop_ACSF4 57 cvskdgklvvvGcydgklycldlatgeilwkfktgd..aiKsspvidsesglvvvgsydknlyaldvesgklvwklklggsifsspllskskes 148 ++s+d++++ G+ dgkl + +++tg+ l +f+ + i + ++ + ++ gs+d +++ ++sgk++ +++ + s + +++ ++++ FUN_001771-T1 271 AFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKAHakGITCVTFS-RDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHN 363 46889999999*********************95441145555444.4556788***************************9999999999*** PP Beta-prop_ACSF4 149 vlvatldGtvaalseesgeilWkvk.lesPiFsspvils........devvvaevdgtvlclseegeklwsvkt...kgpiFsspvlvkseeki 230 ++ a+ dG+v + + ++ e l +k + + + +++ s +++vv++ ++tvl ++ +g+++ s++ +g F +l+++ e + FUN_001771-T1 364 IISASSDGSVKLWNVKTTECLHTFKpAVGSVATDITVNSvhlmprnpEQFVVCNRTSTVLVMNMQGQIVRSFTSgkrDGGDFVCCTLSPRGEWV 457 ********************99998444556666666557788877778***********************9755578889999999****** PP Beta-prop_ACSF4 231 vfgshdgllyclsv.sgellwkveld 255 ++ +d ++yc+s+ +g+l+ ++++ FUN_001771-T1 458 YCVGEDMVMYCFSTmTGKLEQSLQVG 483 ************97479999998875 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.1 0.0 1.2e-08 5.4e-06 26 110 .. 217 308 .. 215 309 .. 0.81 2 ! 13.5 0.3 8e-05 0.035 65 135 .. 306 373 .. 303 388 .. 0.82 3 ? 0.9 0.1 0.55 2.4e+02 74 111 .. 357 394 .. 355 437 .. 0.67 Alignments for each domain: == domain 1 score: 26.1 bits; conditional E-value: 1.2e-08 Beta-prop_VPS8 26 ptalavs...sliavGTshGlvLvFdse.....qtLklclgstakgaeqgaVsalafnadstrllaGyarGqilmwDlsngkllrtisdahpp 110 p+++ s ++++ G G++ v++++ + Lk+ +++ +V +laf++ds l+ G ++G++ +w +++g++lr+ ++ah++ FUN_001771-T1 217 PECVKFSpdgQYLVTGSVDGFIEVYNFTtgkirKDLKYQAQDN-FMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKAHAK 308 6777776666788899999999999875422225677666655.558899****************************************986 PP == domain 2 score: 13.5 bits; conditional E-value: 8e-05 Beta-prop_VPS8 65 eqgaVsalafnadstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikFtddptlalvsDsgGsv 135 + +++++f++d ++ll G + +i+m l++gk+l++ + + v Ft d + ++ s Gsv FUN_001771-T1 306 HAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFR---GHTSFVNDAIFTMDAHNIISASSDGSV 373 55679******************************887764...444556777799999999999999998 PP == domain 3 score: 0.9 bits; conditional E-value: 0.55 Beta-prop_VPS8 74 fnadstrllaGyarGqilmwDlsngkllrtisdahppg 111 f d +++ ++G++ +w++++ ++l+t + a+ FUN_001771-T1 357 FTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSV 394 56788888888999**************9998776444 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0084 3.7 202 251 .. 202 250 .. 189 263 .. 0.70 2 ! 27.5 0.2 6.2e-09 2.7e-06 35 196 .. 262 428 .. 250 438 .. 0.80 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0084 Beta-prop_RIG_2nd 202 letlkkitasaekasitsvkwsnansnlllsfsidgkvkvWdleepekee 251 ++l + ++ +k ++vk+s+ ++l++ s+dg ++v++ +++ + FUN_001771-T1 202 PTQLSRTIKFGTKSHPECVKFSPDG-QYLVTGSVDGFIEVYNFTTGKIRK 250 334444445567778899****976.678899**********99988743 PP == domain 2 score: 27.5 bits; conditional E-value: 6.2e-09 Beta-prop_RIG_2nd 35 kvkskvlsLaWspdkenLAfgTaeGrvGildvekmkvktllrkvlkkeiYslvWkkky..lyvvsnre.lavydak..kkkkeatllkkier 121 +++ +vl+La s d+e LA g ++G+ + v++ + + ++k++ k i ++ + + l+ s ++ + + +k k+ ke ++ + FUN_001771-T1 262 MMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKAHAKGITCVTFSRDAsqLLSGSFDMtIRMHGLKsgKTLKEFRGHTSFVN 353 47899*************************************************87774444433333033333330022233333444444 PP Beta-prop_RIG_2nd 122 vslvsvrdslLlvgtedGalqllerkkelekayskllkqeallsryitdiawsplesnklAvvandkvivilefk 196 +++++ ++ ++ ++dG+++l + k++ + + +k + ++ +++ + p + +++ v+ +++++ +++++ FUN_001771-T1 354 DAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSVATDITVNSVHLMPRNPEQFVVCNRTSTVLVMNMQ 428 5788888999999*************999988888788888889****************************997 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 3.9e-08 1.7e-05 134 249 .. 212 328 .. 192 345 .. 0.77 2 ! 17.6 0.1 6e-06 0.0027 2 74 .. 315 387 .. 314 417 .. 0.86 3 ! 13.8 0.1 8.8e-05 0.039 1 71 [. 356 432 .. 356 440 .. 0.76 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.9e-08 Beta-prop_WDR75_1st 134 dvssnpkaiafGregeyiasvk.glqlevyffkkqktyr.fslkaedk.kGaknaftcvachpkddciatGhedGkirlwrnfnqkkeyt 220 +s+p+++ f +g+y+++ +evy f + k + ++ +a+d+ +++ c+a + + +a+G +dGk+++w+ + + FUN_001771-T1 212 GTKSHPECVKFSPDGQYLVTGSvDGFIEVYNFTTGKIRKdLKYQAQDNfMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRR 301 56789************986441445899999877654324444444314567889999999999***************9988888877 PP Beta-prop_WDR75_1st 221 ystlhwhhdavsslvftpeGtnllsGGve 249 + h + ++ ++f+ + +llsG + FUN_001771-T1 302 FEKA--HAKGITCVTFSRDASQLLSGSFD 328 7665..67899999***********9876 PP == domain 2 score: 17.6 bits; conditional E-value: 6e-06 Beta-prop_WDR75_1st 2 iskdsrfllcasGds.vkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktf 74 +s+d+ ll s d+ ++++ ++ ++++e++ght v ++ h ++ s+s dg+v+lw+ + ++tf FUN_001771-T1 315 FSRDASQLLSGSFDMtIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAH-NIISASSDGSVKLWNVKTTECLHTF 387 789999999999986489*********************999888777.789***********99888777777 PP == domain 3 score: 13.8 bits; conditional E-value: 8.8e-05 Beta-prop_WDR75_1st 1 viskdsrfllcasGd.svkvyststeecvhelkgh.....td.lvtGvalnpsnhlqvyscsldgtvrlwdftdgili 71 +++ d++ ++ as d svk++ +t ec+h++k td v v l p+n q c +tv + ++ ++ FUN_001771-T1 356 IFTMDAHNIISASSDgSVKLWNVKTTECLHTFKPAvgsvaTDiTVNSVHLMPRNPEQFVVCNRTSTVLVMNMQGQ-IV 432 7899***9999988768**************99651111133246789999************999987765443.44 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.73 3.2e+02 39 85 .. 214 258 .. 192 269 .. 0.78 2 ! 17.3 0.0 4.9e-06 0.0022 52 134 .. 275 351 .. 260 357 .. 0.80 3 ! 20.1 0.1 7e-07 0.00031 35 120 .. 342 428 .. 340 439 .. 0.75 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.73 Beta-prop_WDR41 39 kehkdivrflvqiddfrfasagddgivflwdvqtgeillelhghtqk 85 k+h + v+f d +++ + dg++ +++ tg+i +l+ +q+ FUN_001771-T1 214 KSHPECVKFS--PDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAQD 258 5666777764..467778889999***********999888877775 PP == domain 2 score: 17.3 bits; conditional E-value: 4.9e-06 Beta-prop_WDR41 52 ddfrfasagddgivflwdvqtgeillel.hghtqkitaivvfkaekiseeksdliltassdktvivwdiesgrqlkkisdfqst 134 d +as g+dg + +w+vqtg+ l + + h++ it ++ f+++ ++ +l+ s d t+ + ++sg+ lk+ s FUN_001771-T1 275 DSEMLASGGQDGKLKVWKVQTGQCLRRFeKAHAKGITCVT-FSRD------ASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSF 351 666789*******************999457999999875.5443......344789999999999999999999987666665 PP == domain 3 score: 20.1 bits; conditional E-value: 7e-07 Beta-prop_WDR41 35 lsvlkehkdivr.flvqiddfrfasagddgivflwdvqtgeillelhghtqki.taivvfkaekiseeksdliltassdktvivwdie 120 l+ +++h+ v + +d++ ++sa+ dg+v lw+v+t e l ++ + + t i+v + + ++ + + ++ tv+v +++ FUN_001771-T1 342 LKEFRGHTSFVNdAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSVaTDITVNSVHLMPRNPEQFVVCN-RTSTVLVMNMQ 428 566778888776256789****************************999988724577777776777666666654.45677777764 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.0 1.3e-08 5.6e-06 36 186 .. 190 346 .. 182 356 .. 0.78 2 ! 11.1 0.0 0.00053 0.24 65 183 .. 356 478 .. 348 484 .. 0.80 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 1.3e-08 Beta-prop_NUP159_NUP214 36 avt.eeeeeeekelsfkpektisv.prvihvaFssdesalvilaeedgglavydves..lekgnk.epafslstngvsiralkpnp 116 +++ ++eeee+ +++++ +++ ++ v+Fs d+++lv+ + dg + vy++++ ++k k + + ++ + s+ l+ + FUN_001771-T1 190 KAAvKDEEEEKYPTQLSRTIKFGTkSHPECVKFSPDGQYLVT-GSVDGFIEVYNFTTgkIRKDLKyQAQDNFMMMDDSVLCLAFSR 274 444467777777777777777655578999*******98777.7788866666655500554444444444444488999999999 PP Beta-prop_NUP159_NUP214 117 speaellailtsngkLlladlkarslv....svlkenvssfdwsnkgkqlvvgladgtaqqlkpadgevkaeip 186 + +e la ++gkL + ++++++ + ++++++++ s+ +ql+ g+ d t+ + +++g++ +e++ FUN_001771-T1 275 D--SEMLASGGQDGKLKVWKVQTGQCLrrfeKAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFR 346 9..68********************999999*****************************99999888887776 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00053 Beta-prop_NUP159_NUP214 65 aFssdesalvilaeedgglavydveslekgnk.epafslstngvsiralkpnpspeaellailtsngkLlladlkarslv.....s 144 F+ d + +i+a++dg++ +v++ e ++ +pa+ +++++ ++ + p + e++++ + + ++l+++++ + ++ + FUN_001771-T1 356 IFTMDA-HNIISASSDGSVKLWNVKTTECLHTfKPAVGSVATDITVNSVHLMPRN-PEQFVVCNRTSTVLVMNMQGQIVRsftsgK 439 588888.57999****************999999999777777**********96.79****************998876665554 PP Beta-prop_NUP159_NUP214 145 vlkenvssfdwsnkgkqlvvgladgtaqqlkpadgevka 183 + ++ +s +g+ ++++ +d ++ +++ +g+ ++ FUN_001771-T1 440 RDGGDFVCCTLSPRGEWVYCVGEDMVMYCFSTMTGKLEQ 478 444567777888888888888877777777666665555 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.0 3e-08 1.3e-05 5 130 .. 220 348 .. 216 350 .. 0.82 2 ! 11.6 0.1 0.00035 0.15 2 38 .. 352 388 .. 351 425 .. 0.89 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 3e-08 WDR90_beta-prop_4th 5 vvfspdeshlatcsedGsvrvwslas....melvvq....fqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelkl. 85 v fspd + l t s dG + v+ ++ ++l q f ++++s lcla+s s + +++G dG l+v+++ + ++ FUN_001771-T1 220 VKFSPDGQYLVTGSVDGFIEVYNFTTgkirKDLKYQaqdnFMMMDDSVLCLAFSRDS------EMLASGGQDGKLKVWKVQTGQCLRRFe 303 78********************99862222345554334466889999999998655......56999************9877655552 PP WDR90_beta-prop_4th 86 hphavaltaiaysadGqtilsgdkdGlvavssprtGvtlrvlsdh 130 + ha +t +++s d +lsg d + + ++G tl+ ++ h FUN_001771-T1 304 KAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGH 348 68999***********************99999999999988777 PP == domain 2 score: 11.6 bits; conditional E-value: 0.00035 WDR90_beta-prop_4th 2 vnevvfspdeshlatcsedGsvrvwslasmelvvqfq 38 vn+ +f+ d+ ++ + s dGsv++w ++++e + f+ FUN_001771-T1 352 VNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFK 388 89****************************9998876 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.8 0.0 0.0082 3.6 128 168 .. 218 258 .. 212 267 .. 0.77 2 ! 11.6 0.0 0.0003 0.13 124 162 .. 264 302 .. 254 313 .. 0.83 3 ! 7.4 0.0 0.0055 2.4 188 221 .. 306 339 .. 296 341 .. 0.67 4 ! 14.4 1.9 3.9e-05 0.017 96 211 .. 321 442 .. 309 461 .. 0.69 5 ? -0.5 0.2 1.4 6.1e+02 272 296 .. 442 466 .. 414 477 .. 0.68 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0082 NBCH_WD40 128 scvavtsdgsvlatGsydttvmvwevlrarssekrvrntqt 168 cv + dg+ l+tGs d + v++ + +++ + + ++q FUN_001771-T1 218 ECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKDLKYQAQD 258 59**********************99988776554444443 PP == domain 2 score: 11.6 bits; conditional E-value: 0.0003 NBCH_WD40 124 kdvvscvavtsdgsvlatGsydttvmvwevlrarssekr 162 d v c+a + d ++la+G +d + vw+v+ ++ + FUN_001771-T1 264 DDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRF 302 68899*************************987766554 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0055 NBCH_WD40 188 hddiitclfvsveldivisGskdgtcifhtlreG 221 h itc+ s + ++sGs d t +h l++G FUN_001771-T1 306 HAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSG 339 5555667777777777777777777777777666 PP == domain 4 score: 14.4 bits; conditional E-value: 3.9e-05 NBCH_WD40 96 liscGnwensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwevlrarssekr...vrntqtelsrkd.vviaekplh.ilc 186 + G+++ + ++ l+ G+ +++ r h v t d +++ s d +v +w+v ++ + v ++ t+++ ++ +++ +p + ++c FUN_001771-T1 321 QLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFkpaVGSVATDITVNSvHLMPRNPEQfVVC 416 456799999999999999999999999999999999999999999999999999999998776543212356667777666634555666542666 PP NBCH_WD40 187 Ghddiitclfvsveldiv...isGskdg 211 l+++++ +iv sG +dg FUN_001771-T1 417 NRTST--VLVMNMQGQIVrsfTSGKRDG 442 65544..344444444442224566665 PP == domain 5 score: -0.5 bits; conditional E-value: 1.4 NBCH_WD40 272 nGrlnclelsscgeflvcaGdqGqi 296 G + c ls ge++ c G++ + FUN_001771-T1 442 GGDFVCCTLSPRGEWVYCVGEDMVM 466 3668899999999999999987555 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.0 0.004 1.8 319 373 .. 191 245 .. 180 253 .. 0.82 2 ! 21.9 0.0 2.2e-07 9.6e-05 98 187 .. 265 352 .. 247 359 .. 0.88 3 ? 1.9 0.0 0.26 1.1e+02 149 188 .. 356 395 .. 348 406 .. 0.77 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.004 Beta-prop_SPT8 319 nacveefdlkmpskpkstlklpsisGpvsavkslpnekhlliaskdn.irlydlek 373 a+ +e + k p++ ++t+k+ + s p +vk p+++ l+ s d i +y+ ++ FUN_001771-T1 191 AAVKDEEEEKYPTQLSRTIKFGTKSHP-ECVKFSPDGQYLVTGSVDGfIEVYNFTT 245 3455788889***************99.7***************996589999774 PP == domain 2 score: 21.9 bits; conditional E-value: 2.2e-07 Beta-prop_SPT8 98 spvyslevnkealfllsGldnGgitlqgvrydeGriahylkakhsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgatsel 187 v +l+ +++ +l sG ++G +++ v + G+ + + + h++ ++ + ++ + ++lsgs+d i l+ gk+ +e++g+ts + FUN_001771-T1 265 DSVLCLAFSRDSEMLASGGQDGKLKVWKV--QTGQCLRRFEKAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFV 352 5699******************9888777..579999999989********************************************965 PP == domain 3 score: 1.9 bits; conditional E-value: 0.26 Beta-prop_SPT8 149 rlnstedkflsgswdkkilewdlntgkvineykgatsels 188 ++ + ++s+s d + w+++t + + +k a + ++ FUN_001771-T1 356 IFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSVA 395 5556677899999999999999999999999998877765 PP >> Ge1_WD40 WD40 region of Ge1, enhancer of mRNA-decapping protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.014 6.4 185 215 .. 212 242 .. 198 251 .. 0.84 2 ! 9.7 0.1 0.0012 0.53 180 247 .. 259 319 .. 242 328 .. 0.75 3 ! 15.9 0.1 1.6e-05 0.0069 186 236 .. 348 393 .. 320 417 .. 0.82 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.014 Ge1_WD40 185 eedsllveaalspdGtalatasadGlvkffq 215 +s + +spdG l t s dG++ + FUN_001771-T1 212 GTKSHPECVKFSPDGQYLVTGSVDGFIEVYN 242 5566667889*****************9986 PP == domain 2 score: 9.7 bits; conditional E-value: 0.0012 Ge1_WD40 180 GyieieedsllveaalspdGtalatasadGlvkffqiyledneeqrclheWkPhdGkklssllfldnl 247 ++ + +d + + a+s d +la +dG +k +++ + +cl ++ k ++++ f + FUN_001771-T1 259 NFMMM-DD-SVLCLAFSRDSEMLASGGQDGKLKVWKV-----QTGQCLRRFEKAHAKGITCVTFSRDA 319 34433.33.456789********************97.....6789****99999999***9998765 PP == domain 3 score: 15.9 bits; conditional E-value: 1.6e-05 Ge1_WD40 186 edsllveaalspdGtalatasadGlvkffqiyledneeqrclheWkPhdGk 236 ++s + +a ++ d + as dG vk++ + + clh +kP G FUN_001771-T1 348 HTSFVNDAIFTMDAHNIISASSDGSVKLWNV-----KTTECLHTFKPAVGS 393 4569999********************9976.....7889*******9885 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.0 0.024 11 43 57 .. 219 233 .. 204 246 .. 0.83 2 ! 22.2 0.1 2.4e-07 0.0001 37 155 .. 263 380 .. 240 391 .. 0.76 3 ? 1.2 0.0 0.59 2.6e+02 232 279 .. 361 407 .. 349 415 .. 0.68 4 ? 2.2 0.1 0.29 1.3e+02 287 314 .. 443 470 .. 421 477 .. 0.84 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.024 WD40_MABP1-WDR62_1st 43 alafspdGkylvtGe 57 ++ fspdG+ylvtG FUN_001771-T1 219 CVKFSPDGQYLVTGS 233 578**********96 PP == domain 2 score: 22.2 bits; conditional E-value: 2.4e-07 WD40_MABP1-WDR62_1st 37 srkalsalafspdGkylvtGesghlpavrvwdvaeksqvaelq.khkygvacvafspnekyivsvgyqhdmvvnvwdwkkdvvvaa.nk 123 ++ +lafs+d ++l +G g ++vw v+ + + ++ h g++cv+fs + + + s +dm++ ++ k + FUN_001771-T1 263 MDDSVLCLAFSRDSEMLASG--GQDGKLKVWKVQTGQCLRRFEkAHAKGITCVTFSRDASQLLSG--SFDMTIRMHGLKSGKTLKEfRG 347 4467889**********998..455789*******999999862699*************99986..7899999988887655544144 PP WD40_MABP1-WDR62_1st 124 vsskvtavsfsedssyfvtvG.nrhvkfwylda 155 +s v f+ d+ +++ + vk+w +++ FUN_001771-T1 348 HTSFVNDAIFTMDAHNIISASsDGSVKLWNVKT 380 566677777887777777664145677776655 PP == domain 3 score: 1.2 bits; conditional E-value: 0.59 WD40_MABP1-WDR62_1st 232 edlifcgcadGtvrvfkaadlkflatl.pkphalgvdvaavlepsklfs 279 + i+ +++dG v++++ ++ + l t+ p +++d+ ++++ +l+ FUN_001771-T1 361 AHNIISASSDGSVKLWNVKTTECLHTFkPAVGSVATDI--TVNSVHLMP 407 56688999999999999999999877523333444444..455555555 PP == domain 4 score: 2.2 bits; conditional E-value: 0.29 WD40_MABP1-WDR62_1st 287 pdtvavtfdpvnrwlscvyndhslyvwd 314 d v+ t p +w+ cv +d +y + FUN_001771-T1 443 GDFVCCTLSPRGEWVYCVGEDMVMYCFS 470 588999999*************999876 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.023 10 127 160 .. 210 243 .. 200 256 .. 0.77 2 ! 20.0 0.0 8.4e-07 0.00037 17 111 .. 220 326 .. 218 334 .. 0.79 3 ! 8.2 0.1 0.0033 1.5 41 98 .. 338 394 .. 329 458 .. 0.82 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.023 Beta-prop_IFT122_1st 127 khkssskiiccswtndgqylalgmfngiisirnk 160 k+ + s+ c+ ++ dgqyl g ++g i + n FUN_001771-T1 210 KFGTKSHPECVKFSPDGQYLVTGSVDGFIEVYNF 243 4556667779999999999999999999998875 PP == domain 2 score: 20.0 bits; conditional E-value: 8.4e-07 Beta-prop_IFT122_1st 17 iafkpdgtqlilaag.srllvydtsdgtllqplkgh........kdtvycvayakdgkrfasgsadksviiwtsklegilk...ythnd 93 + f pdg l+ + + vy+ + g + + lk + d+v c+a+++d + +asg d + +w + l+ +h FUN_001771-T1 220 VKFSPDGQYLVTGSVdGFIEVYNFTTGKIRKDLKYQaqdnfmmmDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRrfeKAHAK 308 57999999998866514567999999999999885422222222689*************************99887776522258999 PP Beta-prop_IFT122_1st 94 aiqcvsynpithqlascs 111 i cv++ + ql s s FUN_001771-T1 309 GITCVTFSRDASQLLSGS 326 9*******9999999876 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0033 Beta-prop_IFT122_1st 41 dgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegilkythndaiqcv 98 g l+ ++gh v ++ d + + s s+d sv +w k l+ t++ a+ v FUN_001771-T1 338 SGKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLH-TFKPAVGSV 394 6888999*********************************99887764.455555544 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.7 0.1 0.00051 0.22 358 378 .. 277 297 .. 228 302 .. 0.85 2 ! 21.7 0.4 2.4e-07 0.00011 301 399 .. 302 403 .. 297 433 .. 0.80 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00051 Beta-prop_SCAP 358 mvlasGGqdGaiclwdvltGs 378 +lasGGqdG + +w v tG FUN_001771-T1 277 EMLASGGQDGKLKVWKVQTGQ 297 468999999999999999996 PP == domain 2 score: 21.7 bits; conditional E-value: 2.4e-07 Beta-prop_SCAP 301 vqcahqkPitvlk..aaaGrvvtGsqdhtvrvyrledscclftlqGhsGgit.avyidqtmvlasGGqdGaiclwdvltGsrvshvyghrGdvts 392 + ah k it + a ++++Gs d t+r++ l+ l ++Gh+ + a++ ++ + s dG++ lw+v t + G v++ FUN_001771-T1 302 FEKAHAKGITCVTfsRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNdAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPAVGSVAT 396 5679******875215799****************************99885499999999999*************998776666666777777 PP Beta-prop_SCAP 393 lvcttsc 399 + +s+ FUN_001771-T1 397 DITVNSV 403 6666665 PP >> Beta-prop_Vps41 Vps42 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0033 1.4 58 104 .. 217 264 .. 202 267 .. 0.74 2 ! 11.7 0.0 0.00037 0.16 14 89 .. 262 341 .. 256 346 .. 0.80 3 ! 11.0 0.1 0.00058 0.26 45 123 .. 339 421 .. 337 433 .. 0.77 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0033 Beta-prop_Vps41 58 isslsidtdGeylAsaSmDGtvvigslseeee.iavdFkrpvkavald 104 ++++ + dG+yl ++S+DG + +++ ++ + + +++ + +++++d FUN_001771-T1 217 PECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIrKDLKYQAQDNFMMMD 264 45788999******************9998862456787776666655 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00037 Beta-prop_Vps41 14 fskdsvSaclih..ekvlvfgthsGiihildpdg.ntirtf.kahrasisslsidtdGeylAsaSmDGtvvigslseeee 89 + dsv +++++ +++l+ g + G++ + ++++ + +r+f kah++ i++++ ++d++ l s+S D t+ +++l++ ++ FUN_001771-T1 262 MMDDSVLCLAFSrdSEMLASGGQDGKLKVWKVQTgQCLRRFeKAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKT 341 557888898887324688888999999999998746677773688889999****************9999999988765 PP == domain 3 score: 11.0 bits; conditional E-value: 0.00058 Beta-prop_Vps41 45 gntirtfkahrasisslsidtdGeylAsaSmDGtvvigslseeeeiavdFkrpvkavaldpnysk.....sssksfisGgkagk 123 g+t+++f+ h++ +++ d++ + saS DG+v + ++++ e +Fk +v +va d ++++ ++ +f++ +++ FUN_001771-T1 339 GKTLKEFRGHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTT-ECLHTFKPAVGSVATDITVNSvhlmpRNPEQFVVCNRTST 421 688999*********9999*****************9998655.55678**999999999887652222234566666665544 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.0024 1.1 73 114 .. 206 247 .. 200 252 .. 0.90 2 ! 18.7 0.0 2.3e-06 0.001 79 159 .. 262 345 .. 248 350 .. 0.85 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0024 Beta-prop_WDR19_1st 73 tskldtglkdkltfllWskkspiLavGtskGnlllYnkktsk 114 +++ g+k+++ +++ s ++++L+ G+ G + +Yn +t k FUN_001771-T1 206 SRTIKFGTKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGK 247 56789999*****************************99876 PP == domain 2 score: 18.7 bits; conditional E-value: 2.3e-06 Beta-prop_WDR19_1st 79 glkdkltfllWskkspiLavGtskGnlllYnkktskkipilGk.HskkItcgawsken.lLalgseDktltisn.aeGdtlkqi 159 + d++ +l+ s++s++La G + G+l ++ +t + + k H+k Itc ++s++ L gs D t+ + ++G tlk++ FUN_001771-T1 262 MMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKaHAKGITCVTFSRDAsQLLSGSFDMTIRMHGlKSGKTLKEF 345 4678999*****************************99999877***********885268999*****999873557777765 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.025 11 13 39 .. 277 303 .. 264 325 .. 0.76 2 ? 0.7 0.0 1.7 7.5e+02 13 41 .. 320 348 .. 306 360 .. 0.81 3 ! 19.1 0.1 3.1e-06 0.0014 12 40 .. 361 389 .. 352 426 .. 0.68 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.025 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdretkkqvGlFv 39 +++ s +D ++K+W+ +t + + F FUN_001771-T1 277 EMLASGGQDGKLKVWKVQTGQCLRRFE 303 6788999************99888775 PP == domain 2 score: 0.7 bits; conditional E-value: 1.7 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdretkkqvGlFvCe 41 + ++s s D t+++ ++ k + F+ + FUN_001771-T1 320 SQLLSGSFDMTIRMHGLKSGKTLKEFRGH 348 5799**********999999999988765 PP == domain 3 score: 19.1 bits; conditional E-value: 3.1e-06 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkkqvGlFvC 40 + iisAs+D +vKlW+ +t+ + F FUN_001771-T1 361 AHNIISASSDGSVKLWNVKTTECLHTFKP 389 568*****************999988864 PP >> Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.86 3.8e+02 183 208 .. 222 248 .. 202 259 .. 0.82 2 ! 10.5 0.0 0.00054 0.24 174 210 .. 266 300 .. 249 303 .. 0.83 3 ! 15.1 0.1 2.2e-05 0.0096 164 257 .. 344 455 .. 304 465 .. 0.66 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.86 Beta-prop_Nup120_160 183 s.eddtllftvclDhkLRvWslktgkc 208 + +d+++l+t ++D+ + v++ +tgk+ FUN_001771-T1 222 FsPDGQYLVTGSVDGFIEVYNFTTGKI 248 347**********************97 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00054 Beta-prop_Nup120_160 174 astavavveseddtllftvclDhkLRvWslktgkcva 210 + +++a+++ d+++l + +D+kL+vW ++tg+c+ FUN_001771-T1 266 SVLCLAFSR--DSEMLASGGQDGKLKVWKVQTGQCLR 300 556667776..999999999***************85 PP == domain 3 score: 15.1 bits; conditional E-value: 2.2e-05 Beta-prop_Nup120_160 164 ryggrseelsastavavveseddtllftvclDhkLRvWslktgkcvat.idll...................eerdpqesrkkltldps 232 +++g++ s +++ + + d +++ + D+ +++W++kt +c++t + + e++ ++ FUN_001771-T1 344 EFRGHT-----SFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTfKPAVgsvatditvnsvhlmprnpEQFVVCNR--------- 418 444444.....444444444589999**********************55555877665555555554444433333333......... PP Beta-prop_Nup120_160 233 qsnllkvv...................gsdgglylvvtysppse 257 + ++dgg ++++t+sp +e FUN_001771-T1 419 -------TstvlvmnmqgqivrsftsgKRDGGDFVCCTLSPRGE 455 .......1444444445555555599999999********9665 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.8 0.0 0.00026 0.12 179 270 .. 211 305 .. 203 311 .. 0.60 2 ! 10.0 0.0 0.0009 0.39 227 270 .. 347 390 .. 327 408 .. 0.72 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00026 Beta-prop_DCAF4 179 fgtssdvlaqqfalqapllfnGcrsGeifaidlrqrsr.kgkgwka..trlfhdsavtsvqllqeeqlllaadmaGkiklwdlratkcvkqyeG 269 fgt+s + +f+ l G G i ++ + + k +++a ++ d +v ++ ++ ++l + Gk+k+w +++ +c++++e FUN_001771-T1 211 FGTKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIrKDLKYQAqdNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEK 304 5555555555555555566666666644444433322213333333003345566677888888888888888888888888888888888875 PP Beta-prop_DCAF4 270 h 270 FUN_001771-T1 305 A 305 4 PP == domain 2 score: 10.0 bits; conditional E-value: 0.0009 Beta-prop_DCAF4 227 fhdsavtsvqllqeeqlllaadmaGkiklwdlratkcvkqyeGh 270 h s v + + +++a G +klw++++t c++ ++ FUN_001771-T1 347 GHTSFVNDAIFTMDAHNIISASSDGSVKLWNVKTTECLHTFKPA 390 366667666667788889999999*************9999865 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.72 3.2e+02 115 180 .. 219 241 .. 200 264 .. 0.64 2 ! 22.6 0.1 1.5e-07 6.7e-05 112 227 .. 266 383 .. 255 430 .. 0.80 3 ? 1.8 0.0 0.32 1.4e+02 113 148 .. 352 386 .. 334 471 .. 0.83 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.72 Beta-prop_Aladin 115 svaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvw 180 +v++sp+G++Lv++s + v+ FUN_001771-T1 219 CVKFSPDGQYLVTGS-------------------------------------------VDGFIEVY 241 444555555555544...........................................44444444 PP == domain 2 score: 22.6 bits; conditional E-value: 1.5e-07 Beta-prop_Aladin 112 pvtsvaWspkGdlLvsaspvdtsilvWdvaketav.pLrrvggggvsllkwspdgskllaatpssvfrvwetetW.tcerWtvlkgrvqaacw 202 +v ++a+s + ++L+s+ +d ++ vW v++ ++ ++++ ++g++ +++s d+s+ll+++ r++ ++ t + ++ v+ a + FUN_001771-T1 266 SVLCLAFSRDSEMLASGG-QDGKLKVWKVQTGQCLrRFEKAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGkTLKEFRGHTSFVNDAIF 357 7999**********9985.79*************83589999***************************998775155677778888888888 PP Beta-prop_Aladin 203 spdgsvllfateeepv.iyslsfkee 227 + d++ ++ a+++ +v +++++++e FUN_001771-T1 358 TMDAHNIISASSDGSVkLWNVKTTEC 383 88888888777766553666666655 PP == domain 3 score: 1.8 bits; conditional E-value: 0.32 Beta-prop_Aladin 113 vtsvaWspkGdlLvsaspvdtsilvWdvaketavpL 148 v + ++ +++ ++sas d s+ +W+v++ ++ FUN_001771-T1 352 VNDAIFTMDAHNIISAS-SDGSVKLWNVKTTECLHT 386 55555666777788887.589999999999999754 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.0 5.2e-08 2.3e-05 9 148 .. 204 348 .. 197 364 .. 0.82 2 ? 1.4 0.1 0.49 2.2e+02 30 89 .. 362 428 .. 352 448 .. 0.72 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 5.2e-08 Beta-prop_HPS5 9 eLlspirsskRvkytclavsr..kflaLGsstGgvyifsrealk........llqlltakegaistvaispdedlvavatsrglvvvvelnierk 93 +L +i+ +++ + c++ s+ ++l+ Gs G + +++ ++ k + + ++ ++a+s+d +++a ++++g++ v++++ FUN_001771-T1 204 QLSRTIKFGTKSHPECVKFSPdgQYLVTGSVDGFIEVYNFTTGKirkdlkyqAQDNFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQ---- 294 677888888889999999997447*********887777666665577777666678888999***************************7.... PP Beta-prop_HPS5 94 qkpkrlyissehkgskvtaLlWdesssrvyiGdekGkvsvtklssskasalfkvs 148 + l + ++ + + +t+++ ++++s++ +G ++ ++ l+s k+ + f+ FUN_001771-T1 295 -TGQCLRRFEKAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGH 348 .667777777778889*****************9999999999999877766654 PP == domain 2 score: 1.4 bits; conditional E-value: 0.49 Beta-prop_HPS5 30 kflaLGsstGgvyifsrealkllqlltakegaist......vaisp.dedlvavatsrglvvvveln 89 + ++ ss G+v +++ +++++l+++ + g++ t v + p + + + v ++ + v v++++ FUN_001771-T1 362 HNIISASSDGSVKLWNVKTTECLHTFKPAVGSVATditvnsVHLMPrNPEQFVVCNRTSTVLVMNMQ 428 5666678999999999999999999887776654321111166666677788888888888888775 PP >> Beta-prop_NWD2_C NWD2 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.26 1.2e+02 312 338 .. 214 240 .. 209 243 .. 0.82 2 ! 24.6 0.1 4e-08 1.8e-05 14 226 .. 220 435 .. 218 443 .. 0.76 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.26 Beta-prop_NWD2_C 312 qaelkaiestedgksivlgtvDGsltv 338 ++ + ++ + dg+ +v g+vDG + v FUN_001771-T1 214 KSHPECVKFSPDGQYLVTGSVDGFIEV 240 55667788999************8866 PP == domain 2 score: 24.6 bits; conditional E-value: 4e-08 Beta-prop_NWD2_C 14 islaeeaelavtvt.RncvgvWdletgkLlkkladsslgaivt..ha....vitkdgkyvvsa.esgkvliwelekeqvlfkeeqkdvkqlll 98 ++++ + ++ vt + + + v++++tgk+ k l +++ ++ ++ + ++d++++ s + gk+ +w++++ q l++ e+++ k ++ FUN_001771-T1 220 VKFSPDGQYLVTGSvDGFIEVYNFTTGKIRKDLKYQAQDNFMMmdDSvlclAFSRDSEMLASGgQDGKLKVWKVQTGQCLRRFEKAHAKGITC 312 56666666666655146899***********999887765432112211114589999999962678999**********9998877777766 PP Beta-prop_NWD2_C 99 leddtkviavskekeaekkakvvvrsiPegekvyefeyevkkkfkkavltadglflvvlavdksekdvllvynaktGtllekiklkyenikd. 190 ++ + + + + + ++ + + +g+++ ef +++ +++a++t+d ++++ +++d s ++++n+kt ++l+++k+ ++ FUN_001771-T1 313 VTFSRDASQLLSGSF---DMTIRMHGLKSGKTLKEFRGHTSF-VNDAIFTMDAHNIISASSDGS----VKLWNVKTTECLHTFKPAVGSVATd 397 655555544444443...567999999******999999995.999***********9999998....89**************998665432 PP Beta-prop_NWD2_C 191 ..vsalvalphkanqvalidedkgnilDikkkklvrsi 226 v++++ +p++++q ++ ++ + ++ + ++vrs FUN_001771-T1 398 itVNSVHLMPRNPEQFVVCNRTSTVLVMNMQGQIVRSF 435 33889*************99998887777777888875 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.1 2.1e-07 9.4e-05 116 280 .] 218 376 .. 198 376 .. 0.76 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 2.1e-07 Beta-prop_EIPR1 116 sqvLWdleGlqnevksiseealilvsldeskkgke.....vskyslggeelrvaAldphdsslvlvace.sglqliDlRakkkksvanvetlhg 203 ++v ++G v+ + + +++++++k k+ + ++ + ++++ + A+ ds++ + ++ +l+++ + + + + e +h FUN_001771-T1 218 ECVKFSPDGQY-LVTGSVDGFIEVYNFTTGKIRKDlkyqaQDNFMMMDDSVLCLAFS-RDSEMLASGGQdGKLKVWKVQTGQCLR--RFEKAH- 306 55666666633.344444456778888888888776663344555555899999986.68888888888799******9999888..999999. PP Beta-prop_EIPR1 204 fgkvravdfdpakknklltagddgvvlihDiRydgsstveklkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 + +++v f++ + +ll+ d ++ +h ++ + ++lke+++h+ v+ + f + i+s+ssd +kLw FUN_001771-T1 307 AKGITCVTFSRD-ASQLLSGSFDMTIRMHGLK-----SGKTLKEFRGHTSFVNDAIFTMDAHN-IISASSDGSVKLW 376 566789***985.67899*9*****9999999.....6778899*************887766.78*********** PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 2.4e-05 0.011 275 355 .. 214 296 .. 203 308 .. 0.61 2 ! 11.3 0.0 0.00033 0.14 71 120 .. 275 325 .. 267 344 .. 0.64 3 ? 0.1 0.0 0.83 3.6e+02 284 308 .. 358 382 .. 345 440 .. 0.70 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.4e-05 Beta-prop_IFT140_1st 275 ktgkeadiiwaekglLitatgesvirlwdlerdd.nyvLsldeklgfek.gEaincvsyckakgiLaaGtnkGrvalwkkvae 355 k+ e+ + + + L+t + + +i +++ +++ L+ + + +f ++++ c+++++ +++La+G + G++ +wk ++ FUN_001771-T1 214 KSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKiRKDLKYQAQDNFMMmDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTG 296 44444444445555566666666666666655542233555555555432667888888888888888888888888887654 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00033 Beta-prop_IFT140_1st 71 tkkilavgwesGevlvlneqdkel.telpklhkaeitvlewssngsrLvsg 120 ++la g ++G + v++ q++++ +++k+h it++++s +s+L+sg FUN_001771-T1 275 DSEMLASGGQDGKLKVWKVQTGQClRRFEKAHAKGITCVTFSRDASQLLSG 325 345666666666666666666555134566666666666666666666666 PP == domain 3 score: 0.1 bits; conditional E-value: 0.83 Beta-prop_IFT140_1st 284 waekglLitatgesvirlwdlerdd 308 ++++ +i a+ + ++lw++++ + FUN_001771-T1 358 TMDAHNIISASSDGSVKLWNVKTTE 382 4445555555555555555555444 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0031 1.4 160 200 .. 218 259 .. 210 267 .. 0.85 2 ! 9.2 0.1 0.002 0.86 16 49 .. 266 299 .. 260 382 .. 0.77 3 ? -0.5 0.0 1.7 7.3e+02 164 189 .. 357 382 .. 339 436 .. 0.52 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0031 Beta-prop_WDR35_TULP_N 160 akvewspdgklllfglkegevhvyd.segnflsklklkclek 200 +v++spdg++l+ g+ +g + vy+ ++g+ ++lk +++++ FUN_001771-T1 218 ECVKFSPDGQYLVTGSVDGFIEVYNfTTGKIRKDLKYQAQDN 259 579**********************66788888898877665 PP == domain 2 score: 9.2 bits; conditional E-value: 0.002 Beta-prop_WDR35_TULP_N 16 klksvaWnkeqgyiavggedglLkvLklesekke 49 ++ ++a+++++ +a gg+dg Lkv k+++ + FUN_001771-T1 266 SVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCL 299 6889***********************9986543 PP == domain 3 score: -0.5 bits; conditional E-value: 1.7 Beta-prop_WDR35_TULP_N 164 wspdgklllfglkegevhvydsegnf 189 ++ d+++++ ++++g v++++ + + FUN_001771-T1 357 FTMDAHNIISASSDGSVKLWNVKTTE 382 33444455555555555555544333 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.8 0.0 0.00026 0.11 175 243 .. 259 326 .. 239 340 .. 0.85 2 ! 7.5 0.2 0.0054 2.4 107 149 .. 344 387 .. 339 434 .. 0.66 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00026 Beta-prop_DCAF12 175 ssnpgntkvralafsaknqelgavsldGyfhlwkaentlsrllslrlpyarenvcltycdelslyavGs 243 + ++ v lafs+ + l++ dG +++wk++ l+ + ++a+ +c+t++ + s Gs FUN_001771-T1 259 NFMMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTG-QCLRRFEKAHAKGITCVTFSRDASQLLSGS 326 55667788999************************865.56999999**************99877776 PP == domain 2 score: 7.5 bits; conditional E-value: 0.0054 Beta-prop_DCAF12 107 drkghkdwif.aiawlsdtvavsGsrdgtlalwrvdpdklnasi 149 + +gh+ ++ ai + ++s s dg++ lw+v + + +++ FUN_001771-T1 344 EFRGHTSFVNdAIFTMDAHNIISASSDGSVKLWNVKTTECLHTF 387 5689999886356667777899*************986644433 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.4 4.2e-06 0.0018 23 167 .. 266 414 .. 255 439 .. 0.69 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 4.2e-06 WD40_RFWD3 23 llalLvvsqpssnallfkGyGvkkissldlks....sqyiklHskaiRdlaFnseqdslllsaslDktlkltsllsntvvqtYetdspvWsCcWse 114 + +L+ s+ s+ l +G k+++ ++++ +++ k H+k i ++F+ s lls s+D t+++ l+s +++++++ +++ + + FUN_001771-T1 266 SVLCLAFSRDSEM--LASGGQDGKLKVWKVQTgqclRRFEKAHAKGITCVTFSRD-ASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDAIFT 358 5556666666633..345543334444444331111568899**********988.77789***********************999887777666 PP WD40_RFWD3 115 ddsnylyaGlqnGsvlvfDiRqtssevselekee....srspvvsLayvpaaasssl 167 d + + ++Gsv ++ +++t + +++++++ + v s++ +p+++++ + FUN_001771-T1 359 MDAHNIISASSDGSVKLWNVKTT-ECLHTFKPAVgsvaTDITVNSVHLMPRNPEQFV 414 66666667789*********876.567777766322224455666666666666554 PP >> Beta-prop_BBS7 BBS7 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.032 14 235 265 .. 227 256 .. 218 273 .. 0.64 2 ? 6.6 0.0 0.013 5.6 14 55 .. 363 404 .. 358 441 .. 0.73 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.032 Beta-prop_BBS7 235 kdllvGrdDGlvevyslde......edepvlrfeyal 265 + l+ G DG +evy++++ +y+ FUN_001771-T1 227 QYLVTGSVDGFIEVYNFTTgkirkdL-------KYQA 256 56899************985554331.......2222 PP == domain 2 score: 6.6 bits; conditional E-value: 0.013 Beta-prop_BBS7 14 kvvvgdqdGvvqvfsmkkgeaqlvfktlpgkkitrlelgGal 55 ++ + +dG v++ ++k +e ++fk +g+ t +++ + FUN_001771-T1 363 NIISASSDGSVKLWNVKTTECLHTFKPAVGSVATDITVNSVH 404 678899********************9999988888776554 PP >> Beta-prop_IP5PC_F IP5P C-F beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.1 0.1 0.00082 0.36 62 95 .. 263 296 .. 233 308 .. 0.79 2 ? 4.1 0.1 0.055 24 60 143 .. 304 382 .. 300 395 .. 0.72 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00082 Beta-prop_IP5PC_F 62 stsptlclvvdegsklvwsGhkdGkirswkmdqs 95 ++lcl + s ++ sG +dGk++ wk+++ FUN_001771-T1 263 MDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQTG 296 456899************************9865 PP == domain 2 score: 4.1 bits; conditional E-value: 0.055 Beta-prop_IP5PC_F 60 sastsptlclvvdegsklvwsGhkdGkirswkmdqssddtsfkeglswqahrgpvlslviss.yGdlwsgsegGvikvwpwesie 143 a++ ++c+ + + + sG d ir ++ +++++ke ++ h + v+ + ++ ++ s+s +G++k+w ++ e FUN_001771-T1 304 KAHAKGITCVTFSRDASQLLSGSFDMTIRMHGLK---SGKTLKE---FRGHTSFVNDAIFTMdAHNIISASSDGSVKLWNVKTTE 382 5666777888888888888888888888865554...4555555...56677777655555414689999999******988776 PP >> Beta-prop_LRRK2 LRRK2 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 5.1 2.2e+03 121 140 .. 225 244 .. 215 251 .. 0.78 2 ? 12.9 0.0 0.00013 0.058 45 116 .. 251 319 .. 245 331 .. 0.80 3 ? -1.5 0.0 3.1 1.4e+03 81 107 .. 368 394 .. 352 421 .. 0.64 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 5.1 Beta-prop_LRRK2 121 kknlllvGtAdGkLavyeds 140 + ++l+ G dG + vy+ + FUN_001771-T1 225 DGQYLVTGSVDGFIEVYNFT 244 56799999999999999754 PP == domain 2 score: 12.9 bits; conditional E-value: 0.00013 Beta-prop_LRRK2 45 dletekvttqeiddsrvlCLvlvqlpeekedwlvaGtqsgslvvidtedkevkhslqkl.tDaVtsLlfhsks 116 dl+ + +++ ++ d vlCL+ ++++l G q g+l v + ++ +++++ +k +t++ f+ ++ FUN_001771-T1 251 DLKYQAQDNFMMMDDSVLCLAFS----RDSEMLASGGQDGKLKVWKVQTGQCLRRFEKAhAKGITCVTFSRDA 319 5666777777899999****554....5567999*****************9999988625789999998654 PP == domain 3 score: -1.5 bits; conditional E-value: 3.1 Beta-prop_LRRK2 81 tqsgslvvidtedkevkhslqkltDaV 107 gs+ + + +++e++h+ + +V FUN_001771-T1 368 SSDGSVKLWNVKTTECLHTFKPAVGSV 394 444555555555555555555444444 PP >> WD40_like WD40-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.19 84 192 224 .. 210 244 .. 206 262 .. 0.82 2 ? 10.2 0.0 0.0011 0.48 5 78 .. 269 344 .. 265 449 .. 0.68 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.19 WD40_like 192 kievegkPeCilyvdd..ylvvGgdfkylllinik 224 k+ ++++PeC+ ++ d ylv G+ ++ + n+ FUN_001771-T1 210 KFGTKSHPECVKFSPDgqYLVTGSVDGFIEVYNFT 244 6778999***9999655588888888888888876 PP == domain 2 score: 10.2 bits; conditional E-value: 0.0011 WD40_like 5 sidlskkssliayGgkddkctlldlesleevsiies.Fsdsviyvkfldn.dlilvatlDGtileslleneevise 78 + +s +s+++a Gg+d k+++ ++++ + +e+ + v f + ++l ++ D ti ++ l+ ++ ++e FUN_001771-T1 269 CLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEKaHAKGITCVTFSRDaSQLLSGSFDMTIRMHGLKSGKTLKE 344 67899**********************99988777615667777777654258999**********9999985543 PP >> DUF7165 Domain of unknown function (DUF7165) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00035 0.16 62 169 .. 213 328 .. 199 333 .. 0.81 2 ? 0.6 0.0 0.6 2.6e+02 267 306 .. 431 470 .. 416 496 .. 0.76 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00035 DUF7165 62 ilrrPvsatilddgslLavlstelqvdlYdLtkeepkr.......tqslildnsprtialspegsvLaaa.YdggievsslkesalatdrRaVkcd 149 + +P + dg+ L s + +++Y+ t+ + ++ + +++d+s +a+s +++La dg + v +++ + +++ FUN_001771-T1 213 TKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKdlkyqaqDNFMMMDDSVLCLAFSRDSEMLASGgQDGKLKVWKVQTGQCLRRFEKAHAK 308 4556777788899999999999********9998877522222113569*******************8537999********9988777788899 PP DUF7165 150 avDsLaFssdgtqllGttve 169 ++ ++Fs+d +qll + + FUN_001771-T1 309 GITCVTFSRDASQLLSGSFD 328 9**************87765 PP == domain 2 score: 0.6 bits; conditional E-value: 0.6 DUF7165 267 llPstlpaasekGeLvaagfqgkevwlYGvPedldavpea 306 ++ s + + G++v + + ++ w+Y v ed+ + FUN_001771-T1 431 IVRSFTSGKRDGGDFVCCTLSPRGEWVYCVGEDMVMYCFS 470 5556667778889*******************98766544 PP >> RMC1_N Regulator of MON1-CCZ1 complex, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 0.0 0.0067 3 33 76 .. 208 251 .. 191 259 .. 0.80 2 ? 3.5 0.0 0.23 1e+02 31 79 .. 257 304 .. 249 322 .. 0.78 3 ? -1.5 0.0 7.9 3.5e+03 47 77 .. 357 387 .. 329 403 .. 0.73 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0067 RMC1_N 33 sfriedkgpvlsikfSlDkkilavqrssksvefinfaedetsve 76 ++++ k++ +++kfS+D ++l + +e++nf++++ +++ FUN_001771-T1 208 TIKFGTKSHPECVKFSPDGQYLVTGSVDGFIEVYNFTTGKIRKD 251 455566788899************************99876554 PP == domain 2 score: 3.5 bits; conditional E-value: 0.23 RMC1_N 31 plsfriedkgpvlsikfSlDkkilavqrssksvefinfaedetsveysq 79 + +f + d +vl++ fS D+++la ++ ++++++++++++ + + FUN_001771-T1 257 QDNFMMMD-DSVLCLAFSRDSEMLASGGQDGKLKVWKVQTGQCLRRFEK 304 45666665.58**************999999999999988887666654 PP == domain 3 score: -1.5 bits; conditional E-value: 7.9 RMC1_N 47 fSlDkkilavqrssksvefinfaedetsvey 77 f +D + + s+ sv+++n++++e+ +++ FUN_001771-T1 357 FTMDAHNIISASSDGSVKLWNVKTTECLHTF 387 5556555666667777888887776665554 PP >> Beta-prop_WDR75_2nd WD repeat-containing protein 75 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.3 0.00048 0.21 102 233 .. 263 381 .. 252 406 .. 0.78 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00048 Beta-prop_WDR75_2nd 102 hedkitalcfseseesttllvtaskdgkfkvwllaedsdtekesaswscdfvGsyhelkatnccfsedgs.llavsfeevvtvwesetwe 190 +d++ +l fs ++e +l + ++dgk+kvw +++ + ++ + h + t+ +fs d+s ll+ sf+ ++ + ++ + FUN_001771-T1 263 MDDSVLCLAFSRDSE---MLASGGQDGKLKVWKVQTGQCLRR---------FEKAHAKGITCVTFSRDASqLLSGSFDMTIRMHGLKSGK 340 467777777777666...**************9987665543.........3467999999999**998868899999999999999988 PP Beta-prop_WDR75_2nd 191 lkltlcqppgkirdlcfGrlscskyllgttdknllccwnlltc 233 + + + ++d f ++ ++++++++ + wn+ t FUN_001771-T1 341 TLKEFRGHTSFVNDAIFTM--DAHNIISASSDGSVKLWNVKTT 381 8888888888888888864..3556777777777888887765 PP >> KNTC1_N KNTC1, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.1 0.014 6.1 64 98 .. 261 295 .. 199 435 .. 0.79 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.014 KNTC1_N 64 LsfdsevdvvalsqdgqfLlvgersGnlhlihves 98 + d++v ++a+s+d+++L+ g ++G+l + +v++ FUN_001771-T1 261 MMMDDSVLCLAFSRDSEMLASGGQDGKLKVWKVQT 295 33455555555555555555555555555555555 PP >> Hira TUP1-like enhancer of split # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.69 3e+02 8 44 .. 261 299 .. 259 316 .. 0.78 2 ? 5.4 0.0 0.039 17 24 49 .. 364 386 .. 354 407 .. 0.78 3 ? 2.1 0.1 0.42 1.8e+02 14 44 .. 447 477 .. 444 496 .. 0.85 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.69 Hira 8 lvlespasfLecsg..kyLlavtsvgelyvWdikkkkvl 44 ++++ ++ L +s+ ++L ++g+l vW +++ ++l FUN_001771-T1 261 MMMDDSVLCLAFSRdsEMLASGGQDGKLKVWKVQTGQCL 299 5666666666666655666666799**********9997 PP == domain 2 score: 5.4 bits; conditional E-value: 0.039 Hira 24 LlavtsvgelyvWdikkkkvllppes 49 ++ +s+g++ +W++k+ ++l+ + FUN_001771-T1 364 IISASSDGSVKLWNVKTTECLH---T 386 5566899**************9...4 PP == domain 3 score: 2.1 bits; conditional E-value: 0.42 Hira 14 asfLecsgkyLlavtsvgelyvWdikkkkvl 44 ++ L+ +g+++ +v ++ +y++ + + k++ FUN_001771-T1 447 CCTLSPRGEWVYCVGEDMVMYCFSTMTGKLE 477 899999****************999888765 PP >> Beta-prop_RSE1_2nd RSE1/DDB1/CPSF1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.2 0.0054 2.4 151 232 .. 307 428 .. 224 498 .. 0.56 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0054 Beta-prop_RSE1_2nd 151 steitslaiys.....................................ql....seflvvgtwdgtvrifslsdlngldllssqaLsdspe 200 + it+++++ + ++ ++ +++dg+v + +++++++l + +++a++ FUN_001771-T1 307 AKGITCVTFSRdasqllsgsfdmtirmhglksgktlkefrghtsfvndAIftmdAHNIISASSDGSVKLWNVKTTECLHT-FKPAVG---- 392 45555555544777777777777666666666666666666555554411444556667777777777777777777777.777777.... PP Beta-prop_RSE1_2nd 201 essprsllitevlvndlgdk.......sskeeyLligle 232 s ++++ + +v + + + + ++++L++ ++ FUN_001771-T1 393 -SVATDITVNSVHLMPR--NpeqfvvcNRTSTVLVMNMQ 428 .6666665433322221..11123444444444555544 PP >> Beta-prop_IFT140_2nd IFT140 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.014 6.3 113 142 .. 222 251 .. 207 266 .. 0.79 2 ? 2.3 0.2 0.23 1e+02 48 108 .. 371 442 .. 349 463 .. 0.62 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.014 Beta-prop_IFT140_2nd 113 ldvngsfLvvgtdngvikifDlsrReakqh 142 ++ g++Lv g+ g+i +++++ +++ FUN_001771-T1 222 FSPDGQYLVTGSVDGFIEVYNFTTGKIRKD 251 55579****************987666654 PP == domain 2 score: 2.3 bits; conditional E-value: 0.23 Beta-prop_IFT140_2nd 48 kqvvvYelsg....sa.lksvgsfscesevvaih......eqnvytvepnkvqvrtfQGtvkqllsfseaEG 108 +v ++++++ ++ +vgs +++ +v +h eq v++ +++v v+++QG + + ++ + +G FUN_001771-T1 371 GSVKLWNVKTteclHTfKPAVGSVATDITVNSVHlmprnpEQFVVCNRTSTVLVMNMQGQIVRSFTSGKRDG 442 444444444321111102245666665555555444555578888999999999999998766666555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (499 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 778 (0.0304561); expected 510.9 (0.02) Passed bias filter: 740 (0.0289685); expected 510.9 (0.02) Passed Vit filter: 110 (0.00430613); expected 25.5 (0.001) Passed Fwd filter: 58 (0.0022705); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 58 [number of targets reported over threshold] # CPU time: 0.52u 0.42s 00:00:00.94 Elapsed: 00:00:00.44 # Mc/sec: 4568.43 // Query: FUN_001772-T1 [L=267] Description: FUN_001772 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-12 46.7 0.0 6.6e-12 46.1 0.0 1.2 1 MIF4G MIF4G domain Domain annotation for each model (and alignments): >> MIF4G MIF4G domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.1 0.0 2.6e-16 6.6e-12 5 173 .. 48 227 .. 46 231 .. 0.86 Alignments for each domain: == domain 1 score: 46.1 bits; conditional E-value: 2.6e-16 MIF4G 5 kgilnklspenfeklikellklimsd..kellkeiielifekaveepnfipayarLcsalnsrnp..teFgahlleklqeefekreeleeeekgnr 96 + l l+++nf++ l++ i+s+ + ke+++ +++ ++ +f+p+ +++++l s + ++F++ ll +qe +++ +e+ +k++ FUN_001772-T1 48 TEVLGDLTDANFDEKEATLSRYISSSdsPGRIKELVDVLCQRTLKDKEFAPLAGKVANKLCSDESfgGTFRGILLKSTQEIYKN---REDIRKKSV 140 678999**********************99******************************************************...********* PP MIF4G 97 krrlglvrFlgeLykfkl........ltekilfeclkell.ssltked...qprdefnleclltlLetiGkelenekakklmdqflaei 173 ++ gl+ +++eL++ l ++ +l+ell +++ + ++ +e+++ c + L+t+Gk+le ++ ++m +++ + FUN_001772-T1 141 GEWFGLAALICELFNHLRtggaplkvLAG-AVYQTLRELLlIKGDP-SrcqEELEEDEVDCFYQHLKTVGKSLEEADTVSQMAMIFCSV 227 **************977744434331333.3444444444044444.3699999********************888888998888766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (267 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 899 (0.0351928); expected 510.9 (0.02) Passed bias filter: 825 (0.0322959); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2597.65 // Query: FUN_001775-T1 [L=224] Description: FUN_001775 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0081 16.7 15.4 0.012 16.1 14.6 1.7 2 CD20 CD20-like family ------ inclusion threshold ------ 0.28 11.6 2.3 0.72 10.3 2.3 1.6 1 SMK1_alpha_su SMK1 alpha subunit Domain annotation for each model (and alignments): >> CD20 CD20-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 14.6 9.6e-07 0.012 7 95 .. 19 108 .. 10 149 .. 0.73 2 ? -1.1 2.7 0.19 2.4e+03 38 65 .. 88 119 .. 86 201 .. 0.59 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 9.6e-07 CD20 7 IllGllslvlGvilasvsss.stllksgypfwggivfiisGvlgiiaekrstkllvklslllnllslvtavagiillslslalltsaheq 95 ++lG +++l++il ++ t++ g +w++i +i+Gvlg + ++ + +l++l+l+ +++s+++ + +++++ l +++ e+ FUN_001775-T1 19 VILGCGVFTLSFILSKSKDNlGTIFQIGVSYWAAIPIVITGVLGATGGRSGKFTLTRLFLVGSIMSCFLGGILAAFVGFALTAHRMIGEC 108 55666677777777777777*9**************************************999999887665555555555444443333 PP == domain 2 score: -1.1 bits; conditional E-value: 0.19 CD20 38 ggivfiisGvlgiiaekrst....kllvklsl 65 ggi+++++G+ + ++ + + ++ + + FUN_001775-T1 88 GGILAAFVGFALTAHRMIGEcvhvQCPYDTES 119 56666666655555544443322223232222 PP >> SMK1_alpha_su SMK1 alpha subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 2.3 5.7e-05 0.72 13 51 .. 62 102 .. 56 107 .. 0.81 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 5.7e-05 SMK1_alpha_su 13 aaiaGcsGaatfGG..laGGivGciaaGilailqGfevnwh 51 a G sG t+ l G i+ c Gila + Gf + h FUN_001775-T1 62 GATGGRSGKFTLTRlfLVGSIMSCFLGGILAAFVGFALTAH 102 567788888888762268******************98887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (224 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 965 (0.0377765); expected 510.9 (0.02) Passed bias filter: 475 (0.0185946); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2244.71 // Query: FUN_001776-T1 [L=511] Description: FUN_001776 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0039 17.4 6.5 0.017 15.3 6.4 1.9 1 Tetraspanin Tetraspanin family ------ inclusion threshold ------ 0.34 11.8 4.0 0.68 10.8 4.0 1.4 1 CopD Copper resistance protein D 0.52 10.8 7.7 8 7.0 7.7 2.5 1 CD20 CD20-like family 0.59 11.1 1.5 7.6 7.6 0.0 2.5 2 DUF202 Domain of unknown function (DUF202) Domain annotation for each model (and alignments): >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 6.4 2.6e-06 0.017 7 103 .. 15 98 .. 11 191 .. 0.78 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.6e-06 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 7 llnllflllGllllavGvwlksleaassalsesseaaalipvllivlGaviflvgflGccgalkesrcllllyfvlllllflaelaagilafvyrd 102 ++ l+++llGl++++vG+ l ++++++++ + +++Ga +++ g++G +g ++ +l + + ++l++ ++ l ++ +++v + FUN_001776-T1 15 ITGLFTCLLGLACCGVGLKL-----------LEFKKSPSL--PPMIAGAPMVVAGIAGMVGGRIRKSWLVSVHAAFCLVVGVLSLHLINIFVVKEA 97 67799************666...........233444444..5999*****************************999999999987776666666 PP x RF Tetraspanin 103 k 103 k FUN_001776-T1 98 K 98 6 PP >> CopD Copper resistance protein D # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 4.0 0.00011 0.68 21 101 .. 48 134 .. 46 137 .. 0.77 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00011 CopD 21 tGvlnallrvg..legllttayGrlllaKlalvllllalaalnrfrlvprleaa...rkdagaaar.alrrslavelvlgllvlala 101 +G+ +++ + ++g + ++ + ++a ++lv+++l l+++n f++ ++ ++ +k +++ ++ +++ + a+ l+ ++l ++++ FUN_001776-T1 48 AGAPMVVAGIAgmVGGRIRKSWLVSVHAAFCLVVGVLSLHLINIFVVKEAKTRKlhwAKCQSNFQGsKYCHWYAATLGMAVLSVLAV 134 56666666655555777789999*********************9888888777996445555566799999999999998877665 PP >> CD20 CD20-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 7.7 0.0012 8 8 138 .. 22 132 .. 12 188 .. 0.70 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0012 CD20 8 llGllslvlGvilasvsssstllksgypfwggivfiisGvlgiiaekrstkllvklslllnllslvtavagiillslslalltsaheqkeeesdll 103 llGl+++ +G l+ + +s s p ++g+ ++++G+ g + ++ lv+++ +++l+ v+++ i + ++ a+ ++ h FUN_001776-T1 22 LLGLACCGVGLKLLEFKKS----PSLPPMIAGAPMVVAGIAGMVGGRIRKSWLVSVHAAFCLVVGVLSLHLINIFVVKEAKTRKLH---------- 103 5677777777666666666....8889************************99999998877655544444433333333333222.......... PP CD20 104 sststesskssseeeecraylsslkglltgilavl 138 + +++s+ + ++c +y ++l +++l+vl FUN_001776-T1 104 --WAKCQSN-FQGSKYCHWYAATL---GMAVLSVL 132 ..2222222.23444555555555...44444444 PP >> DUF202 Domain of unknown function (DUF202) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.0012 7.6 17 61 .. 24 66 .. 22 72 .. 0.83 2 ? 1.7 0.5 0.077 4.9e+02 39 57 .. 128 146 .. 75 156 .. 0.53 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0012 DUF202 17 slalialgvallrffleggptalakllglilivlgiltllyalvr 61 +la++++g+ ll f ++++ ++ +++g+ ++v+gi+ ++ +++r FUN_001776-T1 24 GLACCGVGLKLLEFKKSPSLPP--MIAGAPMVVAGIAGMVGGRIR 66 6899999999999955555555..****************99988 PP == domain 2 score: 1.7 bits; conditional E-value: 0.077 DUF202 39 lakllglilivlgiltlly 57 + +l+++l+ lgi++ ++ FUN_001776-T1 128 VLSVLAVTLVPLGIICCVT 146 2266777788888777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (511 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1089 (0.0426307); expected 510.9 (0.02) Passed bias filter: 671 (0.0262674); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.42s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4872.59 // Query: FUN_001777-T1 [L=201] Description: FUN_001777 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-39 134.8 0.0 3.3e-39 134.4 0.0 1.2 1 Flavokinase Riboflavin kinase ------ inclusion threshold ------ 0.18 11.7 0.1 1.9 8.5 0.0 2.2 2 UBM Ubiquitin binding region Domain annotation for each model (and alignments): >> Flavokinase Riboflavin kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 134.4 0.0 2.5e-43 3.3e-39 3 123 .] 41 167 .. 39 167 .. 0.92 Alignments for each domain: == domain 1 score: 134.4 bits; conditional E-value: 2.5e-43 Flavokinase 3 rpysleGkVvkGkgrG.relgfPTaNlel.eekllp...keGVYavkvkvegekvykgvaniGvnptfknekksvEvhlldf.egdlygkeievef 92 p++l+G Vv+G +rG ++lg+PTaN+++ + lp ++G+Y+++++v+++ vyk+v++iG+np++kn+kks+E+h+++ e+d+yg+e++v + FUN_001777-T1 41 LPLFLRGYVVHGMRRGgKDLGIPTANFPVsVVENLPeaiSTGIYYGWASVNRGPVYKMVMSIGWNPFYKNTKKSMETHIIHTfEEDFYGAELSVAI 136 5889************9***********864444446778****************************************656************* PP Flavokinase 93 lkflRpekkFdsleaLkeqikkDveearkll 123 ++f+Rpek++ sleaL+++i++D++ea+++l FUN_001777-T1 137 VGFIRPEKNYPSLEALIDAIHADIKEAEQSL 167 ***************************9875 PP >> UBM Ubiquitin binding region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.0 0.00015 1.9 3 22 .. 27 46 .. 25 46 .. 0.89 2 ? 0.7 0.0 0.042 5.4e+02 10 21 .. 67 79 .. 61 79 .. 0.83 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00015 UBM 3 aatpeeiDpsFLaaLPpdLR 22 ++++ e ++s+La+LP LR FUN_001777-T1 27 TSQAREASNSVLAQLPLFLR 46 57788999*********999 PP == domain 2 score: 0.7 bits; conditional E-value: 0.042 UBM 10 Dp.sFLaaLPpdL 21 +p s+ + LP+ + FUN_001777-T1 67 FPvSVVENLPEAI 79 7999******986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 886 (0.0346839); expected 510.9 (0.02) Passed bias filter: 809 (0.0316696); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2011.65 // Query: FUN_001778-T1 [L=972] Description: FUN_001778 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-34 118.2 8.7 6.5e-17 61.5 3.9 2.6 2 KH_1 KH domain 2.4e-29 102.4 0.0 6e-29 101.1 0.0 1.7 1 TUDOR Tudor domain 5.3e-10 39.5 5.9 7.6e-05 23.0 0.3 3.6 3 KH-I_KHDC4-BBP KHDC4/BBP-like, KH-domain type I 9.5e-06 25.8 1.0 0.049 13.9 0.3 2.8 2 KH_NusA_2nd NusA-like second KH domain 1.1e-05 25.6 8.5 0.0028 17.9 3.1 2.9 2 KH_2 KH domain 9.4e-05 22.7 1.2 0.014 15.7 0.1 2.5 2 KH_PNO1_2nd Eukaryotic type KH-domain (KH-domain type I) 0.00014 22.2 5.3 0.47 10.9 0.2 3.9 3 KH_KhpA-B KhpA/KhpB, KH domain 0.0059 17.0 0.0 0.79 10.2 0.0 2.6 2 Tudor-knot RNA binding activity-knot of a chromodomain ------ inclusion threshold ------ 0.046 14.1 0.0 4.2 7.9 0.0 2.4 2 MOEP19 KH-like RNA-binding domain 0.2 12.3 4.5 0.82 10.4 0.3 2.9 2 KH_NusA_1st NusA-like first KH domain Domain annotation for each model (and alignments): >> KH_1 KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.5 3.9 2.5e-20 6.5e-17 1 64 [. 58 125 .. 58 126 .. 0.93 2 ! 58.8 0.2 1.8e-19 4.7e-16 1 64 [. 136 201 .. 136 202 .. 0.92 Alignments for each domain: == domain 1 score: 61.5 bits; conditional E-value: 2.5e-20 KH_1 1 terilvPaskvgriIGkgGstIkeIreetgakIkipsedde....sderivtIsGtpeavekAkelie 64 t++++vP+s vg+iIGk G++Ik+I++e+ga++++++ed++ s+eriv I+G++e ++A+ li+ FUN_001778-T1 58 TVEVKVPRSVVGAIIGKSGANIKRIEKESGARVHLIDEDEGgknvSGERIVFIQGEREMARRAEILIK 125 789*******************************996666669********************99996 PP == domain 2 score: 58.8 bits; conditional E-value: 1.8e-19 KH_1 1 terilvPaskvgriIGkgGstIkeIreetgakIkip.sedde.sderivtIsGtpeavekAkelie 64 t ++ vP++ +griIGkgG+tI+++ + +ga+Iki + d ++ r+++I+Gt +++++Ak l+ FUN_001778-T1 136 TKEFYVPQRACGRIIGKGGQTIRHMCSVSGARIKIDcDGVDLtNPLRKCVITGTSDQIANAKGLLD 201 56899*****************************987666669*******************9875 PP >> TUDOR Tudor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 101.1 0.0 2.3e-32 6e-29 3 120 .. 237 357 .. 235 358 .. 0.97 Alignments for each domain: == domain 1 score: 101.1 bits; conditional E-value: 2.3e-32 TUDOR 3 edetidvvvseiespstfyi.qpkesskkleklteelqeyykskpk..eslkpkvgegcvavfsedgkwyRAkiteslddqkveVlfiDyGntetv 95 ++++++v+vs+i+ p +f++ e+s+ l+klt++l++ y+s ++ + + kvg+ c+a f d +wyRA+i e ++d+ ve++++D+G + ++ FUN_001778-T1 237 TGDFFEVFVSAIDTPDHFWVqLITEDSPHLDKLTKDLTSLYSSLESttVLNAFKVGDICCAPFELDSQWYRARILEMNEDGTVELYYVDFGDSGQI 332 57899***************888999*********************9999********************************************* PP TUDOR 96 plsdlrelpeeleslppqaikcsLa 120 ++++lre+++e ++lp+qai+c L+ FUN_001778-T1 333 SKDKLREIRQEHSKLPFQAIECFLS 357 **********************997 PP >> KH-I_KHDC4-BBP KHDC4/BBP-like, KH-domain type I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.3 3e-08 7.6e-05 7 33 .. 67 93 .. 65 112 .. 0.89 2 ! 17.0 0.1 2.2e-06 0.0055 8 38 .. 146 176 .. 143 202 .. 0.78 3 ? -0.6 0.1 0.69 1.8e+03 31 58 .. 814 843 .. 804 850 .. 0.69 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 3e-08 KH-I_KHDC4-BBP 7 vvgriiGprgsnlkhIenetgakvrlr 33 vvg iiG++g+n+k+Ie+e+ga+v l FUN_001778-T1 67 VVGAIIGKSGANIKRIEKESGARVHLI 93 89**********************985 PP == domain 2 score: 17.0 bits; conditional E-value: 2.2e-06 KH-I_KHDC4-BBP 8 vgriiGprgsnlkhIenetgakvrlrGrGsg 38 +griiG++g++++h+ + +ga++++ G FUN_001778-T1 146 CGRIIGKGGQTIRHMCSVSGARIKIDCDGVD 176 79**********************9887764 PP == domain 3 score: -0.6 bits; conditional E-value: 0.69 KH-I_KHDC4-BBP 31 rlrGrGs..gflepatgeesdeplhllisa 58 + GrGs g+l ++++ e+d + ++sa FUN_001778-T1 814 EVEGRGSdvGKLTGSESPEADSDTESFLSA 843 578899866777777777777766666655 PP >> KH_NusA_2nd NusA-like second KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.9 0.3 1.9e-05 0.049 20 63 .. 53 96 .. 43 99 .. 0.82 2 ! 9.3 0.0 0.00054 1.4 24 59 .. 135 170 .. 118 173 .. 0.80 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.9e-05 KH_NusA_2nd 20 deekkkaevvVpdeqlSlAIGKrGqNvrLaakLtgwkidiksee 63 ++++++ev Vp++ ++ IGK G N++ ++k g ++++ +e+ FUN_001778-T1 53 SANQRTVEVKVPRSVVGAIIGKSGANIKRIEKESGARVHLIDED 96 456699**********************9888888888776665 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00054 KH_NusA_2nd 24 kkaevvVpdeqlSlAIGKrGqNvrLaakLtgwkidi 59 ++ e +Vp+ ++ IGK Gq +r + ++ g +i i FUN_001778-T1 135 RTKEFYVPQRACGRIIGKGGQTIRHMCSVSGARIKI 170 566779************************999988 PP >> KH_2 KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 3.1 1.1e-06 0.0028 23 61 .. 55 93 .. 34 127 .. 0.79 2 ! 9.6 0.5 0.00043 1.1 36 61 .. 146 170 .. 113 179 .. 0.79 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.1e-06 KH_2 23 takavivviresqpgivIGkgGsnikkigkelrkdiekl 61 +++ v+v + s g +IGk G+nik+i+ke + ++ + FUN_001778-T1 55 NQRTVEVKVPRSVVGAIIGKSGANIKRIEKESGARVHLI 93 45889999999**********************999755 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00043 KH_2 36 pgivIGkgGsnikkigkelrkdiekl 61 g +IGkgG++i+ + + + +i+ + FUN_001778-T1 146 CGRIIGKGGQTIRHMCSVSGARIK-I 170 599**********99998888883.5 PP >> KH_PNO1_2nd Eukaryotic type KH-domain (KH-domain type I) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.1 0.012 31 20 48 .. 67 95 .. 52 96 .. 0.89 2 ! 15.7 0.1 5.6e-06 0.014 18 46 .. 143 171 .. 134 181 .. 0.92 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.012 KH_PNO1_2nd 20 aiGRiigkdGktkeaienltktriviadk 48 ++G iigk+G + ie+ +++r+ + d+ FUN_001778-T1 67 VVGAIIGKSGANIKRIEKESGARVHLIDE 95 689*********************99886 PP == domain 2 score: 15.7 bits; conditional E-value: 5.6e-06 KH_PNO1_2nd 18 sRaiGRiigkdGktkeaienltktrivia 46 +Ra GRiigk+G+t + + +++++ri i FUN_001778-T1 143 QRACGRIIGKGGQTIRHMCSVSGARIKID 171 7*************************985 PP >> KH_KhpA-B KhpA/KhpB, KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.9 0.2 0.00018 0.47 20 52 .. 47 80 .. 37 83 .. 0.84 2 ! 10.4 0.1 0.00026 0.66 34 52 .. 140 158 .. 122 166 .. 0.87 3 ? 0.0 0.1 0.44 1.1e+03 22 46 .. 803 828 .. 795 829 .. 0.73 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00018 KH_KhpA-B 20 veee.eeektkelelkvagedlGkvIGkqGrtld 52 +e+ + +++++e+kv + +G +IGk G +++ FUN_001778-T1 47 ENETiASANQRTVEVKVPRSVVGAIIGKSGANIK 80 4555678899********************9997 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00026 KH_KhpA-B 34 kvagedlGkvIGkqGrtld 52 +v + +G++IGk G+t++ FUN_001778-T1 140 YVPQRACGRIIGKGGQTIR 158 6777889**********96 PP == domain 3 score: 0.0 bits; conditional E-value: 0.44 KH_KhpA-B 22 ee.eeektkelelkvagedlGkvIGk 46 + +ee++ e e++ g+d+Gk+ G FUN_001778-T1 803 TViDEEEEYEQEVEGRGSDVGKLTGS 828 44466778888899999*****9885 PP >> Tudor-knot RNA binding activity-knot of a chromodomain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.028 73 7 35 .. 108 141 .. 102 142 .. 0.77 2 ! 10.2 0.0 0.00031 0.79 10 37 .. 300 326 .. 291 329 .. 0.85 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.028 Tudor-knot 7 vlvrkkdgelrlAeilsire.kkgk....yeYYV 35 v+++ + + r+Aeil ++ ++++ +e+YV FUN_001778-T1 108 VFIQGEREMARRAEILIKKIiAEQPvirtKEFYV 141 4555577889*********9655559999****9 PP == domain 2 score: 10.2 bits; conditional E-value: 0.00031 Tudor-knot 10 rkkdgelrlAeilsirekkgkyeYYVHY 37 + d ++++A+il+ +e+ + YYV + FUN_001778-T1 300 EL-DSQWYRARILEMNEDGTVELYYVDF 326 44.89*********************87 PP >> MOEP19 KH-like RNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.0 0.0017 4.2 17 76 .. 61 125 .. 59 133 .. 0.73 2 ? 3.6 0.0 0.036 91 15 48 .. 137 170 .. 128 190 .. 0.86 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0017 MOEP19 17 lyleawlleaiFGpdgeripeiEvvsqtllevekvds.....eglaeilifGrpryqkrvkkmll 76 +++ ++ ai+G++g++i+ iE+ s + +++ d +g+ ++i G++++ +r+ ++ FUN_001778-T1 61 VKVPRSVVGAIIGKSGANIKRIEKESGARVHLIDEDEggknvSGERIVFIQGEREMARRAEILIK 125 567889999*****************998888665542101234445777777777777766665 PP == domain 2 score: 3.6 bits; conditional E-value: 0.036 MOEP19 15 lvlyleawlleaiFGpdgeripeiEvvsqtllev 48 + +y+ ++ +i+G+ g+ i+++ vs + +++ FUN_001778-T1 137 KEFYVPQRACGRIIGKGGQTIRHMCSVSGARIKI 170 569999******************9999877766 PP >> KH_NusA_1st NusA-like first KH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.3 0.00032 0.82 48 76 .. 66 93 .. 36 95 .. 0.81 2 ? 2.3 0.4 0.11 2.7e+02 49 74 .. 145 169 .. 108 170 .. 0.72 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00032 KH_NusA_1st 48 dpvGalvGkkGsrvkaisrelngekidiv 76 + vGa++Gk+G+ +k i +e g ++ + FUN_001778-T1 66 SVVGAIIGKSGANIKRIEKES-GARVHLI 93 68***************9998.9998877 PP == domain 2 score: 2.3 bits; conditional E-value: 0.11 KH_NusA_1st 49 pvGalvGkkGsrvkaisrelngekid 74 ++G ++Gk G+ ++ + + g +i+ FUN_001778-T1 145 ACGRIIGKGGQTIRHMCSVS-GARIK 169 69***********9876543.66666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (972 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1244 (0.0486984); expected 510.9 (0.02) Passed bias filter: 627 (0.0245449); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.43u 0.41s 00:00:00.84 Elapsed: 00:00:00.43 # Mc/sec: 9081.53 // Query: FUN_001779-T1 [L=250] Description: FUN_001779 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-05 25.5 0.3 4.5e-05 24.3 0.3 1.6 1 Ig_3 Immunoglobulin domain 0.00047 20.7 0.0 0.00072 20.0 0.0 1.3 1 I-set Immunoglobulin I-set domain 0.0014 19.3 0.1 0.0041 17.8 0.1 1.8 1 Ig_2 Immunoglobulin domain 0.0014 19.6 7.7 0.0042 18.1 7.7 1.9 1 ShK ShK domain-like ------ inclusion threshold ------ 0.036 14.7 0.0 0.059 14.0 0.0 1.3 1 Gp18_dom_I Tail sheath protein Gp18-like domain I Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.3 0.3 8.9e-09 4.5e-05 13 75 .. 31 91 .. 26 93 .. 0.83 Alignments for each domain: == domain 1 score: 24.3 bits; conditional E-value: 8.9e-09 Ig_3 13 veegesvtLtCeaegnppptitWykngke..lssgstskr...sssssnstLtisnvtredsGtYtCv 75 +eeg ++tL C+ +g ++tW++ + +++g+ r s+++ +stL i+ v++ d G+ +Cv FUN_001779-T1 31 TEEGCNATLLCTQTG----NVTWTRSKTSevIQEGP---RfhpSTVGPYSTLLITTVSEADKGNISCV 91 479********9944....89******966555544...1456************************8 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 1.4e-07 0.00072 12 74 .. 31 91 .. 25 105 .. 0.88 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 1.4e-07 I-set 12 vkeGesaeleckvsGepepevsWlkd..gselkeskrvkvkaeegtatLtIsnvkkeDeGkYtck 74 ++eG +a+l c+ +G+ v+W++ + ++e+ r++ + + +tL I+ v+++D+G+ +c+ FUN_001779-T1 31 TEEGCNATLLCTQTGN----VTWTRSktSEVIQEGPRFHPSTVGPYSTLLITTVSEADKGNISCV 91 6899999999*99998....9**99876889999******************************8 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.1 8.1e-07 0.0041 10 68 .. 30 97 .. 22 106 .. 0.79 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 8.1e-07 Ig_2 10 vvtegesvtLtCsasgnppakytwy..kdgkvlsssqn...........fftsnvsaedsGtYtCtarntkg 68 ++ eg++ tL C+ gn +tw+ k ++v++++++ +++++vs+ d+G+ +C+ + +k+ FUN_001779-T1 30 HTEEGCNATLLCTQTGN----VTWTrsKTSEVIQEGPRfhpstvgpystLLITTVSEADKGNISCVGQEGKI 97 46799********9998....666633777999988887777777776677799************999775 PP >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 7.7 8.3e-07 0.0042 2 37 .] 107 139 .. 106 139 .. 0.84 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 8.3e-07 ShK 2 CvDps..sdCaswaangCnspayqdfmkenCpktCgfC 37 C+D dC ++ C q+++ +nC+k+Cg+C FUN_001779-T1 107 CKDLIstADCQGSLQQ-C----SQAWVMKNCRKSCGLC 139 6655555899999999.*....68************** PP >> Gp18_dom_I Tail sheath protein Gp18-like domain I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 1.2e-05 0.059 26 82 .. 78 138 .. 68 146 .. 0.85 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.2e-05 Gp18_dom_I 26 qtvve.dkGkvtevdkdGkil...svfiPsgkiikyaksigqyPalsdsWtvelsssssGi 82 +tv e dkG++ v+++Gki+ +v i ++ +i+ a g + s++W++ s G+ FUN_001779-T1 78 TTVSEaDKGNISCVGQEGKITisfEVVIVCKDLISTADCQGSLQQCSQAWVMKNCRKSCGL 138 56667799************74446889**********************99888888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (250 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 888 (0.0347622); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2473.68 // Query: FUN_001780-T1 [L=219] Description: FUN_001780 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-34 119.9 0.0 2.2e-34 119.5 0.0 1.1 1 Isochorismatase Isochorismatase domain ------ inclusion threshold ------ 0.084 12.7 0.0 0.097 12.5 0.0 1.1 1 Beta-prop_RIC1_2nd RIC1 second beta propeller domain Domain annotation for each model (and alignments): >> Isochorismatase Isochorismatase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 119.5 0.0 1.7e-38 2.2e-34 1 174 [. 36 184 .. 36 185 .. 0.97 Alignments for each domain: == domain 1 score: 119.5 bits; conditional E-value: 1.7e-38 Isochorismatase 1 taLlviDmQndfvesaveeseeaeevvenikklleaareagipviftrqvhelddakgeldkeeasaalkpgttgaelvpelaplegdvvvdKt 94 ta+l++D+Q++f ++ ++e+++ +++++eaa ++ip+i+t+q+++ + g+t +e+ + +++v+ Kt FUN_001780-T1 36 TAFLLCDIQEKFR----PSIRYFPEIIKVAQRMAEAANILKIPIIATEQYPK-----------------GLGNTVEEIDTS---SFKERVFSKT 105 79***********....***********************************.................999999999888...349******* PP Isochorismatase 95 rfsafsgtdLeeiLrelgiktlvlaGvaTdvCVlatardaldrGyevvvvsDavaslspeeheaalerlaqrfaevitte 174 +fs++ +++ee+L++l+++++vl+G++T+vCVl+t +d+l+++y+v+v++D+v+s++ e+++aler++q ++ v+t+e FUN_001780-T1 106 KFSMV-IPEVEEQLKQLKVENIVLMGIETQVCVLQTTMDLLEKNYNVHVLADGVSSRTMVERMYALERIRQIGGFVTTSE 184 *****.99**********************************************************************97 PP >> Beta-prop_RIC1_2nd RIC1 second beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 7.6e-06 0.097 172 247 .. 87 164 .. 66 202 .. 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 7.6e-06 Beta-prop_RIC1_2nd 172 elvqeislsgivshParvrslswllpelgdpsqdvsvasvl.llvdGklvllqpe.edgeekydmrvladnveyvwls 247 ++v+ei+ s++ ++ + ++s+++pe +++ ++++v++++ + ++ ++++lq + e++y+ +vlad+v + + FUN_001780-T1 87 NTVEEIDTSSFKERVFSKTKFSMVIPEVEEQLKQLKVENIVlMGIETQVCVLQTTmDLLEKNYNVHVLADGVSSRTMV 164 467788888888887774469****************9988366888********99999999********9865544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 694 (0.0271677); expected 510.9 (0.02) Passed bias filter: 513 (0.0200822); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2152.03 // Query: FUN_001781-T1 [L=857] Description: FUN_001781 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-62 211.9 2.1 1.9e-62 211.6 1.3 1.5 2 DPPIV_N Dipeptidyl peptidase IV (DPP IV) N-terminal re 2.3e-55 187.9 0.0 9.1e-55 185.9 0.0 2.0 2 Peptidase_S9 Prolyl oligopeptidase family 1e-13 52.1 0.0 2.2e-13 51.0 0.0 1.6 1 Dpp_8_9_N Dipeptidyl peptidase 8 and 9 N-terminal 7.2e-06 26.4 0.0 2.2e-05 24.8 0.0 1.6 1 Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family) 7.9e-06 26.0 0.0 0.0061 16.6 0.0 2.8 2 BD-FAE BD-FAE 0.0077 16.5 0.1 0.022 15.0 0.1 1.8 1 Esterase Putative esterase ------ inclusion threshold ------ 0.014 16.5 0.1 0.033 15.3 0.1 1.6 1 Abhydrolase_6 Alpha/beta hydrolase family 0.016 15.0 0.1 0.048 13.5 0.0 1.7 2 Hydrolase_4 Serine aminopeptidase, S33 0.019 15.1 0.0 0.13 12.3 0.0 2.2 1 DLH Dienelactone hydrolase family 0.037 13.3 0.1 1.5 8.0 0.1 2.4 1 AXE1 Acetyl xylan esterase (AXE1) 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 PETase PET hydrolase-like 0.11 12.6 0.3 0.26 11.4 0.2 1.7 1 Abhydrolase_1 alpha/beta hydrolase fold Domain annotation for each model (and alignments): >> DPPIV_N Dipeptidyl peptidase IV (DPP IV) N-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.9 4e+03 293 315 .. 58 80 .. 54 87 .. 0.86 2 ! 211.6 1.3 8.8e-66 1.9e-62 36 350 .. 174 558 .. 143 561 .. 0.88 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.9 DPPIV_N 293 dlvyFtatedsplerhlYsvslk 315 +++yF a+ ++ e ++ +v+l FUN_001781-T1 58 NKLYFLAVPFGSRENSIHYVDLP 80 799**************999987 PP == domain 2 score: 211.6 bits; conditional E-value: 8.8e-66 DPPIV_N 36 eelapk.egkiqyakwSPd.gnklayvrdnnLyvkklaegkeiqlTs..dg.....edgifnGvadWvyeEEvlgsnsavwWspdgs......... 113 eel+++ +++ +++k++P+ n +a+v+ n+++v+++ +++e++lT+ +g e+ i++Gva ++++EE +++++++wW p+ + FUN_001781-T1 174 EELPSQtTETKMDPKLCPCdPNLVAFVHCNDVWVNNIITEEERRLTYtnQGsashtEEPISAGVASFIVQEE-FDRYTGYWWQPKFNtdesltrty 268 44444478999*******9899******************888887733556655566788***********.***********999999****** PP DPPIV_N 114 rlaylrideseVpeitlpeytdeeeqypevkeikYPkaGsknptvelgvvdl...asgktv.......evqlpddlkdkdeyitrvkWvsdeksll 199 ++ + ++des+V+ ++++ d ++ +v++++YPkaGs n + +l++v++ +sgk++ +++++ ++ ey+ r W++d++s++ FUN_001781-T1 269 KILFEEVDESAVEVLHIVSGPDGIARNSHVDSYRYPKAGSVNAKSKLKIVEFsidTSGKISdhvieyqMRVPLSEAFPFMEYLVRCGWLPDGESVY 364 *******************999999999************************887777777999988644555677888***************** PP DPPIV_N 200 vqwlnRsqnrlkvvlvda................etgktkvkl..eetsdgWvelkqevafl..krdgsgfiwiserdGykHlylfdldgks.... 271 +++l+R+q++l +v + + + g+ +++ ee++d W+++ + ++fl + + +fiw se +G++Hlyl + +++ FUN_001781-T1 365 AEILDRNQQHLALVQIPVaffvpvnhpanqlltiTEGSPMIEVlaEESNDIWINVADLTHFLraNDSRLQFIWSSEISGFRHLYLATANSNHtltr 460 ****************77788888888777776633444444488*****************87777779*********************9**** PP DPPIV_N 272 ..................pkqlTsGeweVts.ilavdekrdlvyFtatedsplerhlYsvslk..sggeltkltdesgkhyysasfspsakyyvlt 346 ++qlT G+weV+ ++vde+r+l+yF +++d+ple+hlY vs++ e+++lt+++ +h +a++++++ +v+ FUN_001781-T1 461 aragsfiseccihyplvtQQQLTDGDWEVDGkEIWVDENRQLIYFMGNKDTPLEQHLYVVSYAqhGYVEPQRLTQSGFSH--AATLNENFTKFVSV 554 **************999888*********776*******************************6556799**********..************99 PP DPPIV_N 347 ysgp 350 +s+ FUN_001781-T1 555 FSSI 558 9976 PP >> Peptidase_S9 Prolyl oligopeptidase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 1.2 2.6e+03 41 72 .. 509 539 .. 506 544 .. 0.81 2 ! 185.9 0.0 4.3e-58 9.1e-55 4 210 .. 654 857 .] 651 857 .] 0.96 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.2 Peptidase_S9 41 gqnefeDfiaaaeylaeegyvdeerlaitGgS 72 ++ +e+ + +++y+ ++gyv ++rl G S FUN_001781-T1 509 KDTPLEQHLYVVSYA-QHGYVEPQRLTQSGFS 539 666677777777776.899*******999988 PP == domain 2 score: 185.9 bits; conditional E-value: 4.3e-58 Peptidase_S9 4 s.selqllasrGyvvvvanirGsggyGeafhdaikrklgqnefeDfiaaaeylaeeg.yvdeerlaitGgSyGGyltlaalnqrpdlFkaavaeap 97 + +l++ a++Gyvvv+++ rGs+++G +f+ ++k++lgq+e+e+++++++y+a+ + ++d +r+ai+G+SyGGyl+l+ l qrpd+Fk+a+ +ap FUN_001781-T1 654 RfLRLHTIAKLGYVVVIMDCRGSAHRGLQFEGHLKNRLGQVEIEEQVEGLQYVAKATdFIDLSRVAIHGWSYGGYLSLLGLVQRPDVFKVAIVGAP 749 55788999**************************************************************************************** PP Peptidase_S9 98 vvdwlaydsdtdlpfteeymewgnpddneegyeelspysplenvk..aypplLlihGleDdrvppaeslklvaaLqkkgkevellvfpdegHgvgk 191 v+ w ayd+ +te+ym+++ + n+ gy ++s++ +++n + ++++lL++hGl D++v++ +s l+ +L k+ k+++ll++p+e+Hg+++ FUN_001781-T1 750 VTTWEAYDTG----YTERYMNTPAE--NPRGY-KMSSVLNYANRFpdEENRLLIVHGLIDENVHFYHSSLLIGELIKACKPYQLLIYPNERHGIRQ 838 **********....*******8877..*****.9999999999779************************************************** PP Peptidase_S9 192 prnkvkelakllaFlkkal 210 + ++ + ll+Fl+k+l FUN_001781-T1 839 SVSSEHYETMLLSFLQKNL 857 *9999**********9976 PP >> Dpp_8_9_N Dipeptidyl peptidase 8 and 9 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.0 0.0 1e-16 2.2e-13 46 154 .] 24 129 .. 12 129 .. 0.88 Alignments for each domain: == domain 1 score: 51.0 bits; conditional E-value: 1e-16 Dpp_8_9_N 46 eryswsqlkklltdtrkyhgymmakaphdflfvkkndpegphsdrvyylamsgenrentlfyseipktin....kaav..lllswkplldlfqavl 135 +r sw +l+ + +++ ++ ++ + ph f+f +++y+la+ ren++ y ++p + n ++ v + l+wkplld f+ + FUN_001781-T1 24 NRSSWKELQIAVKQAKSVQQSLINRVPHSFTFCE---------NKLYFLAVPFGSRENSIHYVDLPSSENgsrdEQNVdfIPLAWKPLLDSFRISR 110 699*****************************85.........68*********************98774322223322679************* PP Dpp_8_9_N 136 dyglysreeellrerkrig 154 + ysree+llrerkr+g FUN_001781-T1 111 SFSGYSREEQLLRERKRLG 129 *****************98 PP >> Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 1e-08 2.2e-05 46 134 .. 654 755 .. 611 774 .. 0.79 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1e-08 Peptidase_S15 46 e......faarGYavVvqdvrGtggSeGvfevg.....dpqeaedgadvidWlakq.pw.snGkVgmtGiSYlGttqllaaatgvpalkaivpeaa 128 + +a+ GY+vV+ d+rG+ + + +fe ++ e+e ++ ++ +ak + +V++ G SY+G+++ll + ++++ k+++ a+ FUN_001781-T1 654 RflrlhtIAKLGYVVVIMDCRGSAHRGLQFEGHlknrlGQVEIEEQVEGLQYVAKAtDFiDLSRVAIHGWSYGGYLSLLGLVQRPDVFKVAIVGAP 749 34445558999************9876555555666699****************86541458*****************************9999 PP Peptidase_S15 129 isdlyd 134 ++ + + FUN_001781-T1 750 VTTWEA 755 888876 PP >> BD-FAE BD-FAE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 2.9e-06 0.0061 12 106 .. 630 733 .. 619 748 .. 0.74 2 ! 6.1 0.0 0.0045 9.5 164 213 .. 764 815 .. 751 817 .. 0.82 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 2.9e-06 BD-FAE 12 klpvvivihGgaWlsgdkeaqagfmketlkallkkgyavvsieYrlst...........eakfPaqiqDvkaairflranaekykldkskivliGf 96 k+p+v++ +Gg ++ +a++gf l++++k gy+vv ++ r s + i+ + ++++ + a+++ +d s++++ G+ FUN_001781-T1 630 KYPTVLFLYGGPHVQLVTNAHKGFRFLRLHTIAKLGYVVVIMDCRGSAhrglqfeghlkNRLGQVEIEEQVEGLQYVAK-ATDF-IDLSRVAIHGW 723 69**********************9999****************99984433332222111112345566667777754.4444.899******** PP BD-FAE 97 SaGghLalla 106 S Gg L+ll FUN_001781-T1 724 SYGGYLSLLG 733 ******9874 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0045 BD-FAE 164 llgakvaenpelaksasPityvdk...ndpPflivhGekDelVpyeqSkllke 213 +++++ aenp+ +k+ s ++y ++ ++ +livhG De V + +S ll FUN_001781-T1 764 YMNTP-AENPRGYKMSSVLNYANRfpdEENRLLIVHGLIDENVHFYHSSLLIG 815 56655.8999999999999999743337899*****************99865 PP >> Esterase Putative esterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.1 1e-05 0.022 103 155 .. 703 751 .. 609 806 .. 0.62 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1e-05 Esterase 103 lplldanfrtapdg.ralvGqSmGGlgALilalkypdlFgsvssfSpivnpsna 155 l+++++ + + + a+ G S GG+ +L+ +++pd F+ +++ +p+ FUN_001781-T1 703 LQYVAKATDFIDLSrVAIHGWSYGGYLSLLGLVQRPDVFKVAIVGAPV-----T 751 45555554444444589***********************99999987.....3 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.1 1.6e-05 0.033 24 98 .. 662 758 .. 639 812 .. 0.60 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 1.6e-05 Abhydrolase_6 24 laagvrvlapDlpGh...G..ssdpppldlad.v..adladlldelga........gggpvvlvGHSlGGavalaaa....lvag..vllap.... 93 ++ g+ v+ +D++G G +l + + +++++ +++l+ + +v + G+S+GG++ l ++ +v ++ ap FUN_001781-T1 662 AKLGYVVVIMDCRGSahrGlqF----EGHLKNrLgqVEIEEQVEGLQYvakatdfiDLSRVAIHGWSYGGYLSLLGLvqrpDVFKvaIVGAPvttw 753 3335777999999884444221....2222222222444555555555666666788889***************555677444422555555444 PP Abhydrolase_6 94 pvapl 98 ++++ FUN_001781-T1 754 EAYDT 758 22333 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 2.3e-05 0.048 26 116 .. 660 756 .. 649 773 .. 0.85 2 ? -2.4 0.0 1.5 3.3e+03 192 231 .. 793 834 .. 776 836 .. 0.61 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 2.3e-05 Hydrolase_4 26 aLaaqGfavyalDhrGhGkse.......gkrghvpsfddyvdDlaafvekikeehpglplfllGhSmGGaiallylleypdkvkglilsaPalkik 114 a+ G+ v+++D rG + + r ++++ v+ l+ + +k+++ +++++ G S GG+++ll l ++pd +k +i+ aP+ ++ FUN_001781-T1 660 TIAKLGYVVVIMDCRGSAHRGlqfeghlKNRLGQVEIEEQVEGLQYV-AKATDFIDLSRVAIHGWSYGGYLSLLGLVQRPDVFKVAIVGAPVTTWE 754 57899***************999999997777888999999999655.55554444559**********************999*******98877 PP Hydrolase_4 115 ek 116 ++ FUN_001781-T1 755 AY 756 65 PP == domain 2 score: -2.4 bits; conditional E-value: 1.5 Hydrolase_4 192 PllllhGgaDkvvdpagsrelyeragsk..dktlklypglyH 231 ll++hG D+ v+ s l+ ++ ++ +l +yp+ +H FUN_001781-T1 793 RLLIVHGLIDENVHFYHSSLLIGELIKAckPYQLLIYPNERH 834 466777777777666666555555554412345556666666 PP >> DLH Dienelactone hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 6.1e-05 0.13 36 191 .. 660 839 .. 645 848 .. 0.82 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 6.1e-05 DLH 36 klaeeGYvalvPdlYareadpsdkaeaekamrelvskreekvlddleaavnylksrpevsvkkvgvvGfCmGGalalllaakn.eevdaavafyG. 129 +a+ GYv+++ d r+ + + + ++ + l++ + e+ ++ l + v+++ + + ++v++ G+ GG l+ll + + ++ a++ + FUN_001781-T1 660 TIAKLGYVVVIMDC--RGSAHRGLQFEGHLKNRLGQVEIEEQVEGL-QYVAKATDFI--DLSRVAIHGWSYGGYLSLLGLVQRpDVFKVAIVGAPv 750 68999999999996..555456777788888888888855555666.5777777666..889**************99988885666766666669 PP DLH 130 ...........................sspeselaeaekikapilalfgeeDesipadsvekleealkaanvdleikvYpgagHaFand 191 ss+ + + ++ + +l+++g De + + l +l +a +++++ +Yp+ H+ + FUN_001781-T1 751 ttweaydtgyterymntpaenprgykmSSVLNYANRFPDEENRLLIVHGLIDENVHFYHSSLLIGELIKACKPYQLLIYPNERHGIRQS 839 9999999***********9999997666666666777888999*****************************************97655 PP >> AXE1 Acetyl xylan esterase (AXE1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.00071 1.5 61 191 .. 607 731 .. 585 746 .. 0.61 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00071 AXE1 61 fegvkgarikaklvlPkekee..klPavvefhG.Yegr.rgewhellly......aaaGyavlvmdvRGqgglseddtegskdnkakGfiirGlvd 146 +++ +g+++++ + +P + e k P+v+ G + + + h+ + a Gy+v+ md+RG + + +G++ l + FUN_001781-T1 607 YNSKHGHQVYGMIFKPPNIEPgfKYPTVLFLYGgPHVQlVTNAHKGFRFlrlhtiAKLGYVVVIMDCRGSAHR---------GLQFEGHLKNRLGQ 693 6777777777777777655532366776554441322222223332222111222667888888888887622.........23344555433333 PP AXE1 147 gkdklyyrrvflDavrlveivasleevDeeRvvvtGasqGGalal 191 ++ + l +++ + +D +Rv++ G+s GG l+l FUN_001781-T1 694 -------VEIEEQVEGLQYVAKATDFIDLSRVAIHGWSYGGYLSL 731 .......23333344455567777888888888888888888776 PP >> PETase PET hydrolase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00011 0.24 77 163 .. 662 753 .. 657 766 .. 0.65 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00011 PETase 77 ashGfvvitidtnttldqPdsrssqilaaldyvvslasts....sspvankvdtsrlavlGwsmGGGGsliaaknrpsl.kaaiplaPWnte 163 a G+vv+ +d + +++ l +v + ++ ++ ++ +d sr+a+ Gws GG sl +rp++ k ai aP t FUN_001781-T1 662 AKLGYVVVIMDCRGSAHRGLQFEGHLKNRLGQVEIEEQVEglqyVAKATDFIDLSRVAIHGWSYGGYLSLLGLVQRPDVfKVAIVGAPVTTW 753 555666666666555555555555555555555333322211113556788********************999999864888776765443 PP >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.2 0.00012 0.26 1 117 [. 632 754 .. 632 794 .. 0.73 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00012 Abhydrolase_1 1 ppvlllHGlpg.....ssdl.wrk.lapaLakdgfrvialDlrGfGkSsrpkaq....ddyrtddlaedle...ki...ldalglekvnlvGhSlG 79 p+vl+l G+p+ + ++ +r + +ak g+ v+++D rG + + ++ + ++ e++e ++ d +l +v++ G+S+G FUN_001781-T1 632 PTVLFLYGGPHvqlvtNAHKgFRFlRLHTIAKLGYVVVIMDCRGSAHRGLQF-EghlkNRLGQVEIEEQVEglqYVakaTDFIDLSRVAIHGWSYG 726 789999999999988855552555656677888********99988763222.246676666666666666665556669999************* PP Abhydrolase_1 80 Glialayaakypervkalvllgalspaaeldeaarfil 117 G ++l + + p+ v +++ +ga p + ++ FUN_001781-T1 727 GYLSLLGLVQRPD-VFKVAIVGA--P-------VTTWE 754 *************.777777777..2.......33333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (857 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 778 (0.0304561); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.42u 0.41s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 8152.43 // Query: FUN_001782-T1 [L=148] Description: FUN_001782 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-19 70.0 1.5 4.3e-19 69.2 1.5 1.4 1 Snapin_Pallidin Snapin/Pallidin 0.0078 16.1 0.9 0.0094 15.8 0.9 1.3 1 FAP206 Domain of unknown function ------ inclusion threshold ------ 0.015 16.0 8.7 0.38 11.5 0.2 2.2 2 Relaxase_C C-terminal helical hairpin domain from relax 6.5 7.1 14.1 3.5 7.9 6.1 2.1 2 DUF724 Protein of unknown function (DUF724) Domain annotation for each model (and alignments): >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.2 1.5 6.7e-23 4.3e-19 2 89 .] 26 115 .. 25 115 .. 0.97 Alignments for each domain: == domain 1 score: 69.2 bits; conditional E-value: 6.7e-23 Snapin_Pallidin 2 aLaegllellepklkeldeklkelrqsQeeLleqidrlaeeLqeleelqe..evlpdlkeyakKLvnikkrmsslnerlqklqkRaekLq 89 +L +g++ + p l++++ek+ el+q+Q L e++++++++ +++ + + +l+ + +y++KL+++k++ms++++r++kl+kRa+kL+ FUN_001782-T1 26 MLMDGFMHYFMPNLENIQEKIGELTQNQGILIETMQQENDKYADCHSARNlaVMLSYVRTYHAKLTKVKQDMSAIEDRVAKLKKRAMKLK 115 6889***********************************************9999*********************************96 PP >> FAP206 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.9 1.5e-06 0.0094 14 87 .. 40 112 .. 9 122 .. 0.87 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.5e-06 FAP206 14 ekeleeaqelaykytalleklkeetsksevseeqlerlkqalvnvrqyeaflkiLlsdvekcaqeveslqkrle 87 e+ e+ el +++ l+e + ++++++ + ++++++l +l +vr y+a l+ +++d++ ++ v +l+kr + FUN_001782-T1 40 ENIQEKIGELTQNQGILIETM-QQENDKYADCHSARNLAVMLSYVRTYHAKLTKVKQDMSAIEDRVAKLKKRAM 112 444455556667788899999.99999999**************************************999876 PP >> Relaxase_C C-terminal helical hairpin domain from relaxase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.2 6e-05 0.38 41 70 .. 38 65 .. 6 79 .. 0.79 2 ? 7.8 3.6 0.00084 5.4 33 89 .. 88 142 .. 84 147 .. 0.84 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 6e-05 Relaxase_C 41 eLkeLdekiaeLnklakvllnlesdelekr 70 +L++++eki eL++ + +l++ +e+ FUN_001782-T1 38 NLENIQEKIGELTQNQGILIETMQ--QEND 65 799***************999875..3333 PP == domain 2 score: 7.8 bits; conditional E-value: 0.00084 Relaxase_C 33 ealeeadkeLkeLdekiaeLnklakvllnlesdelekrklakailekmnltesitle 89 ++l ++++ ++++++++a+L k a +l + e+e+r++a+a k++l+ ++t + FUN_001782-T1 88 AKLTKVKQDMSAIEDRVAKLKKRAMKLKFQK--EKEDRSKAEAYERKLELERQLTAK 142 57899******************99987766..688899999999999998887765 PP >> DUF724 Protein of unknown function (DUF724) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 1.1 0.0073 46 106 165 .. 15 72 .. 2 81 .. 0.67 2 ? 7.9 6.1 0.00055 3.5 122 174 .. 87 139 .. 72 146 .. 0.81 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.0073 DUF724 106 klleelkklekkiaeeesekrkleeeidelekkilelerqeallkekkeakdkeiarlks 165 k++e++ ++++ +++ + + + +++++++ki el +++ +l e +++++ + a+ +s FUN_001782-T1 15 KKEEKRDDVKEMLMDGFM--HYFMPNLENIQEKIGELTQNQGILIETMQQENDKYADCHS 72 444555555555554443..3445666799*******99999998888887777777666 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00055 DUF724 122 esekrkleeeidelekkilelerqeallkekkeakdkeiarlkseaekleqei 174 +++ +k++++++ +e ++++l+++++ lk +ke++d++ a+ + +le+++ FUN_001782-T1 87 HAKLTKVKQDMSAIEDRVAKLKKRAMKLKFQKEKEDRSKAEAYERKLELERQL 139 56778999999999999999999999999999999998888777666666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (148 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2871 (0.11239); expected 510.9 (0.02) Passed bias filter: 691 (0.0270503); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1482.16 // Query: FUN_001783-T1 [L=336] Description: FUN_001783 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.7e-19 69.2 0.2 8.9e-19 68.3 0.2 1.5 1 CUB CUB domain 1.7e-07 32.3 0.6 9.1e-06 26.7 0.2 2.9 2 CUB_animal Animal CUB domain ------ inclusion threshold ------ 0.077 13.1 0.0 0.17 11.9 0.0 1.5 1 CDCP1_CUB_6 CDCP1 CUB domain Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.3 0.2 1e-22 8.9e-19 1 110 [] 18 136 .. 18 136 .. 0.83 Alignments for each domain: == domain 1 score: 68.3 bits; conditional E-value: 1e-22 CUB 1 CggeltessgsisspnypkeYeenkeCvweirvekgks.vklkfedfeleeeee..caydyvevrd...geeasskllgkfcGsekpediksssnq 90 C++ ++sg i+spnyp+ Y+++++C+w +++e+ +k++f++f+l+ + + c +dyv ++ +++ +++l gkfcGs+ p+ +++ +++ FUN_001783-T1 18 CENWRSSPSGAIQSPNYPSAYPHEQKCTWFVSIEDSVVdIKVSFSSFNLQPKLDgeC-KDYVAIYRlllNKDPRATLAGKFCGSSFPKSMRIAESS 112 666667899************************998755**********97654547.9*****974435555689******************** PP CUB 91 llikfvsdesv....skkGFkaty 110 +++fvsd+ + s GF+++y FUN_001783-T1 113 FTVQFVSDSGHetsnSYTGFSLYY 136 *******98651111556888877 PP >> CUB_animal Animal CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.2 1.1e-09 9.1e-06 3 154 .. 17 137 .. 15 139 .. 0.86 2 ? -0.4 0.0 0.24 2e+03 46 73 .. 242 268 .. 220 321 .. 0.63 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 1.1e-09 CUB_animal 3 gClQYftgtsGtikSFNyddtsggrylnnqnYaiCirreegfcsieysacsdaksfslsgdaeaeaaslvgtaasvgtaectsdyllipgaseed. 97 +C + +++sG i+S Ny + y+++q+ + + e + i++s +s f+l+ + + ++dy+ i ++ FUN_001783-T1 17 NCENWRSSPSGAIQSPNYP----SAYPHEQKCTWFVSIEDSVVDIKVSFSS----FNLQPKLDG----------------ECKDYVAIYRLLLNKd 88 5777778899999999999....5699999999999999999999998885....888777655................468******9988777 PP CUB_animal 98 ataltadrfCgnslnaeagstssvvissskPfvlrvvtdedeseadeenrGFsLnYt 154 a+ a +fCg+s+++ ++ + f +++v+d+ ++ ++++ +GFsL Y+ FUN_001783-T1 89 PRATLAGKFCGSSFPK-------SMRIAESSFTVQFVSDSGHE-TSNSYTGFSLYYE 137 8899************.......77778899***********9.99**********7 PP == domain 2 score: -0.4 bits; conditional E-value: 0.24 CUB_animal 46 sieysacsdaksfslsgdaeaeaaslvg 73 +++ + + +++f+l++++++++++ + FUN_001783-T1 242 QMQTQDPP-QRPFTLQSSDSENSDNDGN 268 33333333.6888888887776655333 PP >> CDCP1_CUB_6 CDCP1 CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 2e-05 0.17 17 51 .. 28 63 .. 20 79 .. 0.80 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 2e-05 CDCP1_CUB_6 17 lLatPnwpeGmkpsstvsWivsvpskq.kaelkfln 51 +++Pn+p++ ++++ +W vs+ + + +++f++ FUN_001783-T1 28 AIQSPNYPSAYPHEQKCTWFVSIEDSVvDIKVSFSS 63 689********************8764156777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 901 (0.0352711); expected 510.9 (0.02) Passed bias filter: 695 (0.0272069); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3374.48 // Query: FUN_001784-T1 [L=1504] Description: FUN_001784 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-96 323.6 17.4 4.4e-59 201.1 7.9 2.3 2 WD40_RLD RCC1-like domain 1.5e-62 211.9 0.1 3.5e-62 210.7 0.1 1.7 1 Pkinase Protein kinase domain 1.3e-58 195.8 14.0 1.9e-13 51.2 0.3 6.3 6 RCC1 Regulator of chromosome condensation (RCC1) r 6.5e-42 144.1 0.0 1.3e-41 143.2 0.0 1.5 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 2.2e-30 104.1 25.7 2e-05 24.7 0.0 6.7 6 RCC1_2 Regulator of chromosome condensation (RCC1) r 3.3e-11 43.4 2.4 0.00044 20.0 0.5 4.0 3 Alsin_RLD Alsin RCC1-like domain 9.1e-05 22.7 0.0 0.00019 21.7 0.0 1.6 1 DUF4347 Domain of unknown function (DUF4347) 0.00018 21.3 0.1 0.00041 20.1 0.1 1.5 1 ABC1 ABC1 atypical kinase-like domain 0.0002 21.2 0.0 0.0002 21.2 0.0 1.8 1 Kinase-like Kinase-like ------ inclusion threshold ------ 0.1 12.7 0.0 0.19 11.9 0.0 1.3 1 HCV_NS2 Hepatitis C virus non-structural protein NS2 0.11 12.4 0.1 20 4.9 0.0 2.7 2 Mcl1_mid Minichromosome loss protein, Mcl1, middle reg 0.24 10.4 10.5 0.51 9.3 10.5 1.5 1 Herpes_UL6 Herpesvirus UL6 like Domain annotation for each model (and alignments): >> WD40_RLD RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 137.7 2.0 3.8e-43 8.2e-40 189 357 .. 514 688 .. 482 689 .. 0.85 2 ! 201.1 7.9 2.1e-62 4.4e-59 36 328 .. 528 830 .. 528 864 .. 0.83 Alignments for each domain: == domain 1 score: 137.7 bits; conditional E-value: 3.8e-43 WD40_RLD 189 lvpkkv...gkvvdiaaGsyhsfaltedgkvyawGlNnygqlGlgstenrvsPtkv.eeslkgvkqiagGehhslaltedgevyawGrndygqlGl 280 p ++ g++++i+ G+ h +++t + v++wG+N++gqlG+g+ + r +P +v + + k++ ++++G ++++++t++g v+++G ++ g lG+ FUN_001784-T1 514 MWPVEMpakGQLREISVGNSHVAMVTMEHAVFTWGSNSCGQLGHGDCNRRDKPIQVeALQSKSILRVCCGGDFTVFVTDNGIVMTCGMGELGCLGH 609 33444454477*********************************************4445555889****************************** PP WD40_RLD 281 geeeeesePtkvpglegvkvvqiaaGsehslavtedgkvyswGfgesgqlGlgdeeedvvePtlve.l.k.kkvvsvsaG 357 g+ +++s+P+ ++ l + +v+ +++G h ++vt+dg v++wG+g++g+lG+gde +++ Pt+v + + ++ +v +G FUN_001784-T1 610 GDWSNSSKPKLIEALLSFDVTCVSCGPAHVAVVTSDGIVFTWGCGNDGRLGHGDE-DNQCLPTEVVaIdDtVSIKQVKCG 688 *999999*************99*******************************76.45788***997533578899*999 PP == domain 2 score: 201.1 bits; conditional E-value: 2.1e-62 WD40_RLD 36 vaaGgmhtlaltedGkvyswGvndegaLGrdteeeeesestPkevegeveelegk.vvqvaaGdshslaltedGevyawGrnseGqlGlgeekkqk 130 +++G+ h++++t + v++wG+n+ g+LG+++ + + +P +ve+ l++k + +v++G ++++++t++G v+++G ++ G lG+g+ ++++ FUN_001784-T1 528 ISVGNSHVAMVTMEHAVFTWGSNSCGQLGHGDCN---RRDKPIQVEA----LQSKsILRVCCGGDFTVFVTDNGIVMTCGMGELGCLGHGDWSNSS 616 689999***********************99966...5677877776....66655999***********99********999******9999999 PP WD40_RLD 131 tPvkvveklekekvkkiaaGanhslaltedgevytwGsgeqgqLgkkserrresklealvpkkv.....gk.vvdiaaGsyhsfaltedgkvyawG 220 +P+++ e l + +v+ +++G h++++t+dg v+twG+g+ g+Lg ++++ ++ p++v ++ ++++ +G + +++lt++g ++a+G FUN_001784-T1 617 KPKLI-EALLSFDVTCVSCGPAHVAVVTSDGIVFTWGCGNDGRLG------HGDEDNQCLPTEVvaiddTVsIKQVKCGFDGTMFLTDTGALLACG 705 **777.8899999999***********************99****......55556666777755676423699999******************* PP WD40_RLD 221 lNnygqlGl................gstenrv.....sPtkv.eeslkgvkqiagGehhslaltedgevyawGrndygqlGlgeeeeesePtkvpg 294 +N +++lGl +Pt v s + v +++ G +hs+al e g vy++G+n+ gql g+ + ++ P+ v+ FUN_001784-T1 706 SNANNKLGLnnrqgflvqmknllnkV-----QvdgknVPTAVkVLSKHRVLDVSLGANHSAALVEPGLVYTFGDNQMGQLACGNCKPRDVPAIVKA 796 *********88888888887665442.....02344578877334444488999**************************9998888999999999 PP WD40_RLD 295 legvkvvqiaaGsehslavtedgkvyswGfgesg 328 le+++ + +G +++a t++++++ wG s FUN_001784-T1 797 LEDKTTAMVFCGDGFTVAGTNENDLFFWGTRPSD 830 *99999889*******************987664 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 210.7 0.1 1.6e-65 3.5e-62 1 259 [. 222 471 .. 222 473 .. 0.95 Alignments for each domain: == domain 1 score: 210.7 bits; conditional E-value: 1.6e-65 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdlls.rkga 94 +e+++++G+G++g ++ ++k+++ +v +K+i+ ++ + ++++ +++E k+l+kl+ hpni+ ++d+fe + +l++ +Ey++gg+l+++l ++ FUN_001784-T1 222 FEKIRTVGKGAYGAAVLYRKKDDDSLVILKEISLHELTATERQMAMNEAKVLSKLSlHPNIISYYDSFEVDGTLMIEMEYADGGTLAQYLGkLEKD 317 68899*************************************************************************************944566 PP Pkinase 95 lseeeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYmAPEvlkskkygkkvDvWslGvilyel 190 ++e+++ i++q+l++l+y+H ++++HrDlK++Ni+++++g +K+ DFG++k+le s+ ++++ gt++Y++PE+ ++k+y +k+DvW++G+ilye+ FUN_001784-T1 318 MEERDILIIFQQMLSALKYIHGNNILHRDLKTANIFLTKEGVVKLGDFGISKQLEGSK-ANTVLGTPYYISPEMCEGKEYNHKSDVWAMGCILYEM 412 ********************************************************98.************************************* PP Pkinase 191 ltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqh 259 +++ f++++ v+k+++ + p + s+e++ l+ ++l+kdp++R+ ++ell++ FUN_001784-T1 413 ASRQKTFEGSNLPALVNKIMKG----------QFAPIRGNYSPEFRLLVADILQKDPDHRPEVDELLHE 471 ********88888877777777..........456888999************************9986 PP >> RCC1 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 2.7 5.8e+03 36 49 .. 524 537 .. 514 538 .. 0.73 2 ! 51.2 0.3 8.9e-17 1.9e-13 3 50 .] 543 590 .. 541 590 .. 0.96 3 ! 32.5 0.3 6.3e-11 1.3e-07 2 50 .] 594 642 .. 593 642 .. 0.95 4 ! 49.2 0.1 3.9e-16 8.2e-13 1 50 [] 645 695 .. 645 695 .. 0.96 5 ! 29.9 0.1 4.2e-10 8.9e-07 2 50 .] 699 763 .. 698 763 .. 0.85 6 ! 37.9 0.0 1.3e-12 2.8e-09 2 49 .. 767 814 .. 766 814 .. 0.98 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.7 RCC1 36 kvvqvacGadhtva 49 +++G++h++ FUN_001784-T1 524 QLREISVGNSHVAM 537 67789******986 PP == domain 2 score: 51.2 bits; conditional E-value: 8.9e-17 RCC1 3 rvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 v+tWG+n+ GqLG+g+ +++ +P +ve l+++ + v+cG+d+tv++ FUN_001784-T1 543 AVFTWGSNSCGQLGHGDCNRRDKPIQVEALQSKSILRVCCGGDFTVFV 590 7********************************************986 PP == domain 3 score: 32.5 bits; conditional E-value: 6.3e-11 RCC1 2 GrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtval 50 G v t+G++e G+LG+g+ +++++P+++e l + +v+ v+cG h++++ FUN_001784-T1 594 GIVMTCGMGELGCLGHGDWSNSSKPKLIEALLSFDVTCVSCGPAHVAVV 642 7788*****************************************9986 PP == domain 4 score: 49.2 bits; conditional E-value: 3.9e-16 RCC1 1 dGrvytWGrneyGqLGlgteesklvPqkveslsgn.kvvqvacGadhtval 50 dG v+tWG++++G+LG+g+e+++++P+ v +++ ++qv cG d t++l FUN_001784-T1 645 DGIVFTWGCGNDGRLGHGDEDNQCLPTEVVAIDDTvSIKQVKCGFDGTMFL 695 89***************************9999999********9999986 PP == domain 5 score: 29.9 bits; conditional E-value: 4.2e-10 RCC1 2 GrvytWGrneyGqLGlgte...........esk......lvPqkveslsgnkvvqvacGadhtval 50 G + ++G+n + LGl+++ + k +vP+ v+ ls+++v +v+ Ga+h++al FUN_001784-T1 699 GALLACGSNANNKLGLNNRqgflvqmknllN-KvqvdgkNVPTAVKVLSKHRVLDVSLGANHSAAL 763 899*************999777766655541.156677799***********************97 PP == domain 6 score: 37.9 bits; conditional E-value: 1.3e-12 RCC1 2 GrvytWGrneyGqLGlgteesklvPqkveslsgnkvvqvacGadhtva 49 G vyt+G n+ GqL g+ + + vP v+ l+++ +v cG+ +tva FUN_001784-T1 767 GLVYTFGDNQMGQLACGNCKPRDVPAIVKALEDKTTAMVFCGDGFTVA 814 99********************************************98 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 143.2 0.0 6e-45 1.3e-41 3 256 .. 224 470 .. 222 472 .. 0.92 Alignments for each domain: == domain 1 score: 143.2 bits; conditional E-value: 6e-45 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtl.keeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrkk 95 +++G+Ga+G + + k +++ V++K + +e + +e++ ++eak+++kl hpni++++ +++l+i +ey++gG+L ++L k FUN_001784-T1 224 KIRTVGKGAYGAAVLYRKK----DDDSLVILKEIsLHELTATERQMAMNEAKVLSKLsLHPNIISYYDSFEVDGTLMIEMEYADGGTLAQYLGKL 314 56899******87765555....89999****995567778889999**********88************************************ PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDvWsf 190 +++++ +++l + +q+ ++++y++ ++++Hrdl + N++++++ vvk++DfG+++++ + +k+++ +++pE+ + k++++ksDvW+ FUN_001784-T1 315 EKDMEERDILIIFQQMLSALKYIHGNNILHRDLKTANIFLTKEGVVKLGDFGISKQL----EGSKANTVLGTPYYISPEMCEGKEYNHKSDVWAM 405 *********************************************************....444455555666799******************* PP PK_Tyr_Ser-Thr 191 GvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelve 256 G +l+E+++ ++ ++g + +++++ +g+ + n ++e l+++ ++dp++Rp+++el++ FUN_001784-T1 406 GCILYEMAS-RQKTFEGSNLPALVNKIMKGQFAPIRGNYSPEFRLLVADILQKDPDHRPEVDELLH 470 ********9.7999***********************************************99975 PP >> RCC1_2 Regulator of chromosome condensation (RCC1) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.1 1e-07 0.00022 3 30 .] 527 554 .. 526 554 .. 0.97 2 ! 18.9 1.1 6.4e-07 0.0014 3 29 .. 579 605 .. 577 606 .. 0.90 3 ! 24.5 1.9 1.1e-08 2.4e-05 1 29 [. 629 657 .. 629 658 .. 0.96 4 ! 23.4 0.1 2.5e-08 5.3e-05 1 28 [. 682 709 .. 682 711 .. 0.95 5 ! 24.7 0.0 9.5e-09 2e-05 2 30 .] 751 779 .. 750 779 .. 0.96 6 ? 4.2 0.5 0.026 56 4 24 .. 805 825 .. 805 826 .. 0.95 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 1e-07 RCC1_2 3 svaaGdnHslaLtsdGrvycwGdNsyGQ 30 +++G++H +t + v++wG+Ns+GQ FUN_001784-T1 527 EISVGNSHVAMVTMEHAVFTWGSNSCGQ 554 59*************************9 PP == domain 2 score: 18.9 bits; conditional E-value: 6.4e-07 RCC1_2 3 svaaGdnHslaLtsdGrvycwGdNsyG 29 v++G+++++++t++G v+++G ++ G FUN_001784-T1 579 RVCCGGDFTVFVTDNGIVMTCGMGELG 605 599*******************98877 PP == domain 3 score: 24.5 bits; conditional E-value: 1.1e-08 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsyG 29 v+ v++G H ++tsdG v++wG++++G FUN_001784-T1 629 VTCVSCGPAHVAVVTSDGIVFTWGCGNDG 657 789***********************999 PP == domain 4 score: 23.4 bits; conditional E-value: 2.5e-08 RCC1_2 1 vvsvaaGdnHslaLtsdGrvycwGdNsy 28 +++v +G++ + +Lt++G ++++G+N + FUN_001784-T1 682 IKQVKCGFDGTMFLTDTGALLACGSNAN 709 89************************87 PP == domain 5 score: 24.7 bits; conditional E-value: 9.5e-09 RCC1_2 2 vsvaaGdnHslaLtsdGrvycwGdNsyGQ 30 +v+ G+nHs aL + G vy++GdN+ GQ FUN_001784-T1 751 LDVSLGANHSAALVEPGLVYTFGDNQMGQ 779 58**************************9 PP == domain 6 score: 4.2 bits; conditional E-value: 0.026 RCC1_2 4 vaaGdnHslaLtsdGrvycwG 24 v +Gd +++a t++++++ wG FUN_001784-T1 805 VFCGDGFTVAGTNENDLFFWG 825 78****************999 PP >> Alsin_RLD Alsin RCC1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.1 1.5e-05 0.032 250 306 .. 541 597 .. 533 602 .. 0.89 2 ! 20.0 0.5 2.1e-07 0.00044 253 362 .. 596 702 .. 591 730 .. 0.80 3 ! 7.0 0.0 0.0018 3.9 253 311 .. 769 827 .. 754 848 .. 0.90 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.5e-05 Alsin_RLD 250 ntqlftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrly 306 + +ft G++ G lG Gd +r++ ++e l++ + + +G + tv t +G + FUN_001784-T1 541 EHAVFTWGSNSCGQLGHGDCNRRDKPIQVEALQSKSILRVCCGGDFTVFVTDNGIVM 597 5679********************************************999887665 PP == domain 2 score: 20.0 bits; conditional E-value: 2.1e-07 Alsin_RLD 253 lftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwGlndkeqlgn..ieelsspleislaeqllpveqvtaleat 346 ++t G + G lG Gd + ++ +e l + v +++G h v t dG ++ wG + +lg ++ p+e+ ++++ ++qv FUN_001784-T1 596 VMTCGMGELGCLGHGDWSNSSKPKLIEALLSFDVTCVSCGPAHVAVVTSDGIVFTWGCGNDGRLGHgdEDNQCLPTEVVAIDDTVSIKQV-----K 686 678999999*******************************************************97545667889999888877776665.....5 PP Alsin_RLD 347 cGdyrtlllnaaGqiq 362 cG t++l +G + FUN_001784-T1 687 CGFDGTMFLTDTGALL 702 7776777776666655 PP == domain 3 score: 7.0 bits; conditional E-value: 0.0018 Alsin_RLD 253 lftlGasnkGllGtGdhikrasvarlekldevGvcsiaaGkehtvvrtldGrlyhwGln 311 ++t+G + G l G+ r+ a ++ l++ + +G tv+ t + l+ wG FUN_001784-T1 769 VYTFGDNQMGQLACGNCKPRDVPAIVKALEDKTTAMVFCGDGFTVAGTNENDLFFWGTR 827 79*******************************************************75 PP >> DUF4347 Domain of unknown function (DUF4347) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.0 9.1e-08 0.00019 1 132 [. 43 187 .. 43 214 .. 0.78 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 9.1e-08 DUF4347 1 vvfiDsavedyqsLvagvkegvevvvldae....rdgleqitealagrknvdaihivshGsegelqLgns..qlsaetlekyaeelaqwgkals.. 88 +vf++s+v + L a+++++v ++ ++ + + l q++e+l+grk v++i ++ hG+ + L ++ q+ + + k ++l+++ +l FUN_001784-T1 43 LVFVSSKVRQSAVLNAAARSSVIFLPYKYDnttlDSLLLQVQETLNGRK-VESIAFLVHGQGSNTVLCSNddQVFLLHAVKDVDDLQNFFLQLVkd 137 79****************998888887776333334567999***9999.**********888777766535666666666667777766555555 PP DUF4347 89 ......edadillYgCnvAageaGeefveklaeltgadvaAsddltGnaa 132 ++a + + +C +A++++ e+v+ l++l++++v ++ +G + FUN_001784-T1 138 fldansPGARLDFLSCPLAQSSDALEIVQFLEDLVNVSVGMTKEIMGTTI 187 55566699*******************************99999999864 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.1 1.9e-07 0.00041 145 221 .. 296 374 .. 286 384 .. 0.81 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.9e-07 ABC1 145 vLtmeyvdGikiddlealeeagidrkeiaeklvel..fleqifedgffhaDphpGNllvrkdgelvllDfGlmgeldek 221 ++ mey dG + ++ e+ +++++i + ++ l+ i ++++h D+ +N++++k+g + l DfG++++l+ + FUN_001784-T1 296 MIEMEYADGGTLAQYLGKLEKDMEERDILIIFQQMlsALKYIHGNNILHRDLKTANIFLTKEGVVKLGDFGISKQLEGS 374 677*********98776666778888777666655115788888999***************************99765 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.0 9.5e-08 0.0002 148 288 .. 324 461 .. 271 462 .. 0.76 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 9.5e-08 Kinase-like 148 lllTlqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvvseve..kgfaPpEllgsrgglytrknktlmtfkldaWqlGlvI 241 l++ q++ +++ + ++h +++ n++l ++g v+lg+f+ + + ++v + pE++ + +k d+W++G + FUN_001784-T1 324 LIIFQQMLSALKYIHGNNILHRDLKTANIFLTKEGVVKLGDFGISKQLEGSKANTVLgtPYYISPEMCEG----------KEYNHKSDVWAMGCIL 409 56667888889999****************************9766655555555543345778888876..........356799********** PP Kinase-like 242 ysiwclklPltlva.eeakeew...ifklck.kipekvklLlkkllrysqed 288 y +++ + +++ + + ++ +f +++ + + +lL++ +l+ + ++ FUN_001784-T1 410 YEMASRQKTFEGSNlPALVNKImkgQFAPIRgNYSPEFRLLVADILQKDPDH 461 ****988777654312222222333688888877777888888888877665 PP >> HCV_NS2 Hepatitis C virus non-structural protein NS2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 8.9e-05 0.19 138 189 .. 509 558 .. 502 559 .. 0.93 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 8.9e-05 HCV_NS2 138 ylYdHlgplsdwaaegLrdlavAvEPvvfspmekkiitwgadtlaCGdivaG 189 ++Y + p++ a+ +Lr++ v v++ me ++ twg + +CG++ +G FUN_001784-T1 509 LIYTNMWPVEMPAKGQLREISVGNSHVAMVTMEHAVFTWGSN--SCGQLGHG 558 58999***********************************86..8**98665 PP >> Mcl1_mid Minichromosome loss protein, Mcl1, middle region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.016 33 93 125 .. 512 544 .. 487 551 .. 0.78 2 ? 4.9 0.0 0.0095 20 81 125 .. 602 648 .. 584 652 .. 0.72 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.016 Mcl1_mid 93 nseWsvklpegEevtavalgkswvavaTskgyl 125 ++ W v++p++ + + +++g+s va++T ++ + FUN_001784-T1 512 TNMWPVEMPAKGQLREISVGNSHVAMVTMEHAV 544 478******99*****************88766 PP == domain 2 score: 4.9 bits; conditional E-value: 0.0095 Mcl1_mid 81 stlvyrpleswanseWsvklpeg..EevtavalgkswvavaTskgyl 125 + l + + +w+ns+ + +++ +vt+v++g vav+Ts g++ FUN_001784-T1 602 GELGCLGHGDWSNSSKPKLIEALlsFDVTCVSCGPAHVAVVTSDGIV 648 566677777776554444444445579****************9987 PP >> Herpes_UL6 Herpesvirus UL6 like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 10.5 0.00024 0.51 340 438 .. 1354 1456 .. 1337 1495 .. 0.67 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00024 Herpes_UL6 340 Gfgkggaaqssekte.qglkksvsnsvikcleeqineqfdtiekLkkenelllkkikeleteLsrl...reeekkeakarevdlltsstdasle 429 +g gg++ ss++ + + +++v +++ + e+ ++ ++ie+Lk+e+e +++++++ ++eL+ + r e+++eak++e +l+++ ++e FUN_001784-T1 1354 RVGAGGKMASSDTRSgNTRRDQVLEELRRESAEKQANLQKEIERLKQEKEEFERRVQQHRKELELAektRYEQQREAKEKEEKLSNEVLNLKIE 1447 3566666655544440444677777776655555566779*********************998771113333335555555555555555555 PP Herpes_UL6 430 nlpesssls 438 +s +l+ FUN_001784-T1 1448 LSKQSDKLQ 1456 444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1504 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2959 (0.115835); expected 510.9 (0.02) Passed bias filter: 724 (0.0283421); expected 510.9 (0.02) Passed Vit filter: 145 (0.00567626); expected 25.5 (0.001) Passed Fwd filter: 47 (0.00183989); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.69u 0.43s 00:00:01.11 Elapsed: 00:00:00.45 # Mc/sec: 13552.60 // Query: FUN_001785-T1 [L=68] Description: FUN_001785 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (68 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 269 (0.0105304); expected 510.9 (0.02) Passed bias filter: 237 (0.00927775); expected 510.9 (0.02) Passed Vit filter: 10 (0.000391466); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.37s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 701.73 // Query: FUN_001786-T1 [L=1527] Description: FUN_001786 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-25 86.5 17.0 2.1e-06 28.0 0.0 7.7 7 Arm Armadillo/beta-catenin-like repeat 9e-11 42.8 0.0 4.8e-10 40.5 0.0 2.4 1 APC_rep Adenomatous polyposis coli (APC) repeat 6.8e-09 36.0 10.0 9.3e-06 25.7 2.1 3.4 3 ARM_ARMC5 ARMC5 ------ inclusion threshold ------ 0.026 13.2 0.8 0.048 12.3 0.1 1.7 2 CFA69_ARM_rpt Cilia- and flagella-associated protein 69, ARM 0.033 13.3 0.1 0.061 12.4 0.1 1.5 1 ZER1-like_2nd Protein zer-1 homolog-like, C-terminal domain 0.23 12.3 2.1 4.1 8.2 0.1 3.7 3 HEAT_2 HEAT repeats Domain annotation for each model (and alignments): >> Arm Armadillo/beta-catenin-like repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.7 0.0 7.2e-05 0.31 6 26 .. 647 667 .. 642 670 .. 0.85 2 ? 3.8 0.0 0.021 91 3 22 .. 755 774 .. 754 781 .. 0.84 3 ! 7.8 0.2 0.0012 5.2 13 40 .. 819 847 .. 818 848 .. 0.94 4 ! 11.2 0.3 0.0001 0.43 4 41 .] 854 892 .. 852 892 .. 0.96 5 ! 10.5 0.0 0.00017 0.71 2 41 .] 895 939 .. 894 939 .. 0.90 6 ! 28.0 0.0 5e-10 2.1e-06 3 41 .] 946 984 .. 944 984 .. 0.92 7 ! 18.9 0.4 3.7e-07 0.0016 5 40 .. 990 1025 .. 986 1026 .. 0.92 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 7.2e-05 Arm 6 qavieaGavppLvrLLsspde 26 a++++G++p L++LL+ +d+ FUN_001786-T1 647 AAMRQSGCLPLLIDLLHGKDF 667 6899************98775 PP == domain 2 score: 3.8 bits; conditional E-value: 0.021 Arm 3 enkqavieaGavppLvrLLs 22 +++ a++e+G++++ +LL+ FUN_001786-T1 755 DHRNAICELGGLQAIAELLQ 774 57889**************9 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0012 Arm 13 avppLvrLLs.spdeevqeeAawALsNLa 40 a+++ v L+ + ee+++++a L+NL+ FUN_001786-T1 819 AIDAIVAQLQtIEEEEIIQVSASVLRNLS 847 68999***********************8 PP == domain 4 score: 11.2 bits; conditional E-value: 0.0001 Arm 4 nkqavieaGavppLvrLLs.spdeevqeeAawALsNLaa 41 +++++++aGa+ +L++ + e ++ + AL+NL+a FUN_001786-T1 854 CRKTLRDAGAINALLSAAQaVHGEPALRTTLSALWNLSA 892 7899*********************************96 PP == domain 5 score: 10.5 bits; conditional E-value: 0.00017 Arm 2 penkqavi.eaGavppLvrLLs....spdeevqeeAawALsNLaa 41 ++nk +++ + Ga++ Lv++L+ s++ +v+e + + L+NL++ FUN_001786-T1 895 SDNKAEMCaSPGALKFLVKCLNysspSGNISVVESSGGILRNLSS 939 5666777779*********************************96 PP == domain 6 score: 28.0 bits; conditional E-value: 5e-10 Arm 3 enkqavieaGavppLvrLLsspdeevqeeAawALsNLaa 41 + ++++++ G+ ++Lv+ L+sp+ +v++++++AL+NL+a FUN_001786-T1 946 DYRKTLRDGGCFQVLVSHLRSPSLRVLSNVCGALWNLSA 984 567888888****************************96 PP == domain 7 score: 18.9 bits; conditional E-value: 3.7e-07 Arm 5 kqavieaGavppLvrLLsspdeevqeeAawALsNLa 40 ++++e+Gav L +L +s++ + +++a+AL+NL FUN_001786-T1 990 QEVLWELGAVSLLKSLVKSKNKAISQASAAALRNLM 1025 5789******************************97 PP >> APC_rep Adenomatous polyposis coli (APC) repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.5 0.0 1.1e-13 4.8e-10 2 72 .. 691 759 .. 690 760 .. 0.78 Alignments for each domain: == domain 1 score: 40.5 bits; conditional E-value: 1.1e-13 APC_rep 2 qPDdkaarrevrvLklleqiraYsetcwdwletesrGvegaaavPsPiekqiiqavcalmklsfDeeyRra 72 + Dd+++rrevrvL+lle ra+++ ++ ++ + + P ++ + +av+almklsf+e++R a FUN_001786-T1 691 NVDDRRGRREVRVLRLLEIARAHCDAVQ-FKGYPVH-PCAERWYPPLRNHGPSPAVAALMKLSFEEDHRNA 759 679**********************874.4433332.22223555445899******************99 PP >> ARM_ARMC5 ARMC5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.012 53 173 259 .. 630 670 .. 574 686 .. 0.60 2 ! 25.7 2.1 2.2e-09 9.3e-06 90 255 .. 743 919 .. 738 928 .. 0.69 3 ! 14.1 0.5 7.8e-06 0.033 57 185 .. 893 1027 .. 886 1031 .. 0.77 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.012 ARM_ARMC5 173 elalkvllnlcqqsevRpaLGnagaiellieelkkesdaskaesskeelvnaLcllcreavNRvkvreagGLelllslLkdssyekl 259 + ++ll +++++ ++a +r++g L+ll++lL ++++++ FUN_001786-T1 630 DDMSRTLLAMSHSKDSCAA----------------------------------------------MRQSGCLPLLIDLLHGKDFTNM 670 3334444444444444444..............................................4455555555555544444443 PP == domain 2 score: 25.7 bits; conditional E-value: 2.2e-09 ARM_ARMC5 90 avRalriLwdtkekreeilesgavravaellsseeeea.....lvkavlkalaeltkgc.....seecaeqvqegkglkelvslase.kkksikel 174 av al L+ +++r+ i+e g+++a+aell+ ++ + +++l+++a +t + +++ + ++ +v+ +++ ++++i ++ FUN_001786-T1 743 AVAALMKLSFEEDHRNAICELGGLQAIAELLQIDHQVNerckdFYSTSLRKYAGMTLTNltfgnTKNKNVLCSFPAAIDAIVAQLQTiEEEEIIQV 838 67789999999*********************86443322222444556655554322111111333222233345677777766654677899** PP ARM_ARMC5 175 alkvllnlc..qqsevRpaLGnagaiellieelkkesdaskaesskeelvnaLc.llcreavNRvkv.reagGLelllslLkdss 255 + +vl nl+ + +R +L agai++l++ +++ ++ ++ ++aL l ++++ N++ + + g L++l+++L+ ss FUN_001786-T1 839 SASVLRNLSwrAEELCRKTLRDAGAINALLSAAQAVHG---EPA-LRTTLSALWnLSAHCSDNKAEMcASPGALKFLVKCLNYSS 919 ********9334556****************8888754...443.45666666515568999****9566688********9665 PP == domain 3 score: 14.1 bits; conditional E-value: 7.8e-06 ARM_ARMC5 57 edken.aealheagvvpalvellketedse...tlqmavRalriLwd...t.kekreeilesgavravaellsseeeealvkavlkalaeltkg 142 ++++n ae + + g+ ++lv++l+ ++ s + lr+L++ + + r+++ g +++++++l s ++ + ++v al +l+++ FUN_001786-T1 893 HCSDNkAEMCASPGALKFLVKCLNYSSPSGnisVVESSGGILRNLSShiaVrADYRKTLRDGGCFQVLVSHLRS-PSLRVLSNVCGALWNLSAR 985 444441666777899******99887665422266788889999999443224567788888889999999998.5678899999********* PP ARM_ARMC5 143 cseecaeqvqegkglkelvslasekkksikelalkvllnlcqq 185 c e+ e ++++ l+sl+++k+k i++++ ++l nl+ + FUN_001786-T1 986 CVEDQEVL-WELGAVSLLKSLVKSKNKAISQASAAALRNLMAV 1027 *9886544.45679**************************976 PP >> CFA69_ARM_rpt Cilia- and flagella-associated protein 69, ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 1.1e-05 0.048 86 230 .. 750 897 .. 748 912 .. 0.85 2 ? -1.3 0.1 0.15 6.4e+02 191 256 .. 952 1016 .. 891 1026 .. 0.61 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 1.1e-05 CFA69_ARM_rpt 86 ltyaqivveslsqlgylmrvps.sevrkqickslislyseeakkq...eveklqptskeykqklveksdlaetlvkslallendlevklkllkvlq 177 l+++++ +++++lg l + + ++ +q+ + +++ys++ +k ++++l +++ k+ l+ ++v l+++e++ ++++ +vl+ FUN_001786-T1 750 LSFEEDHRNAICELGGLQAIAElLQIDHQVNERCKDFYSTSLRKYagmTLTNLTFGNTKNKNVLCSFPAAIDAIVAQLQTIEEEEIIQVS-ASVLR 844 568899999********99976369*************987665411155666666778888899999999***********98888887.59*** PP CFA69_ARM_rpt 178 llssssaknCdqmlkaeaaekicsklndpDpsgqllfrsveilWnllekgske 230 ls ++++ C++ l+ +a + +++ ++ + l + lWnl + s + FUN_001786-T1 845 NLSWRAEELCRKTLRDAGAINALLSAAQAVHGEPALRTTLSALWNLSAHCSDN 897 **************9999999999999998999999999*******8877654 PP == domain 2 score: -1.3 bits; conditional E-value: 0.15 CFA69_ARM_rpt 191 lkaeaaekicsklndpDpsgqllfrsveilWnllekg.skeevakqlnnlecisaLkeafvkllleg 256 + ++ + ++s+l + ps ++l + lWnl + + +ev l ++ +++L ++ k + ++ FUN_001786-T1 952 RDGGCFQVLVSHLRS--PSLRVLSNVCGALWNLSARCvEDQEVLWELGAVSLLKSLVKSKNKAISQA 1016 344555667777765..69999999999999999888556677777777776666666555555554 PP >> ZER1-like_2nd Protein zer-1 homolog-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 1.4e-05 0.061 69 197 .. 810 936 .. 775 1029 .. 0.75 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.4e-05 ZER1-like_2nd 69 qevlfeyerlvklllkilekeeedelvqriavallnslackvegeqkeavgelgaiekllelieeklekkvvdevlevawsaLWNlTdetpancer 164 ++vl ++ ++ ++ l++ ee+e++ +++ +l l + e+ ++++ ++gai+ ll+ + + + + l++++saLWNl + +n + FUN_001786-T1 810 KNVLCSFPAAIDAIVAQLQTIEEEEII-QVSASVLRNLSWRAEELCRKTLRDAGAINALLSAAQ----AVHGEPALRTTLSALWNLSAHCSDNKAE 900 567788889999999999999777766.577889999999*******************98655....45567899*************9999888 PP ZER1-like_2nd 165 FldekG.lelflecleefseke..ellrnmlGllgN 197 + G l++ ++cl+ s +++ G+l N FUN_001786-T1 901 MCASPGaLKFLVKCLNYSSPSGniSVVESSGGILRN 936 888777467778998754433211555555566655 PP >> HEAT_2 HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.32 1.4e+03 23 62 .. 588 628 .. 587 651 .. 0.74 2 ? -0.5 0.1 0.5 2.1e+03 27 73 .. 858 917 .. 820 929 .. 0.61 3 ? 8.2 0.1 0.00097 4.1 3 58 .. 959 1024 .. 957 1039 .. 0.87 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.32 HEAT_2 23 aLgeigdpealpaLlellkdedpavRraaakaLgki.gdpe 62 aL + +++++++ +++++d ++R +++L ++ g+++ FUN_001786-T1 588 ALEGFETSSVVSFASTAATHHDLDTRIDMVQSLLSMlGTHD 628 67788889999999999999999999999999854436533 PP == domain 2 score: -0.5 bits; conditional E-value: 0.5 HEAT_2 27 igdpealpaLlellk..dedpavRra..aakaLgki....g.....dpealpaLlellad 73 ++d+ a++aLl++++ + +pa R + a++ L++ + +p al++L+++l+ FUN_001786-T1 858 LRDAGAINALLSAAQavHGEPALRTTlsALWNLSAHcsdnKaemcaSPGALKFLVKCLNY 917 566677777777774124445444321144444433222202222256666666666655 PP == domain 3 score: 8.2 bits; conditional E-value: 0.00097 HEAT_2 3 aLlqaLlkdpdpevraaairaLgeigdp...........ealpaLlellkdedpavRraaakaLgki 58 +L++ L ++p+ v +++ aL +++ + a+++L +l+k++++a+ +a a aL + FUN_001786-T1 959 VLVSHL-RSPSLRVLSNVCGALWNLSARcvedqevlwelGAVSLLKSLVKSKNKAISQASAAALRNL 1024 788999.9999999999999999888777778888888889***********************876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1527 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1012 (0.0396164); expected 510.9 (0.02) Passed bias filter: 552 (0.0216089); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.51u 0.38s 00:00:00.89 Elapsed: 00:00:00.43 # Mc/sec: 14258.97 // Query: FUN_001787-T1 [L=2688] Description: FUN_001787 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-91 308.2 3.4 1.3e-91 308.2 3.4 2.4 2 TPR_Epg5 Epg5-like, TPR repeats 3.2e-40 138.2 0.1 8.2e-40 136.9 0.1 1.7 1 TPR_Epg5_2 Epg5-like, TPR repeats 3.5e-13 50.0 0.0 1.8e-10 41.1 0.0 2.6 2 TPR_Epg5_C Epg5-like, C-terminal TPR repeats ------ inclusion threshold ------ 0.057 14.0 0.0 1.3 9.6 0.0 3.0 2 RA_2 RA like domain 0.2 11.4 0.6 1.3 8.8 0.0 2.3 2 DUF8137 Domain of unknown function (DUF8137) Domain annotation for each model (and alignments): >> TPR_Epg5 Epg5-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.5 0.25 1.3e+03 160 210 .. 1437 1487 .. 1428 1494 .. 0.79 2 ! 308.2 3.4 2.6e-95 1.3e-91 1 389 [] 1800 2174 .. 1800 2174 .. 0.97 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.25 TPR_Epg5 160 esssksleelrqfaqsqkllslqqvketiellsehfkkeRlsdlgsfgLYs 210 +++ k ++e ++++ ++ +++++++t + +s++f++ + + ++ g+Y+ FUN_001787-T1 1437 KERLKATSEHHRSKSVETAADHDTLTDTNSDISKQFEQTKVLHEKLAGFYQ 1487 33334456777888899999******************9998888888887 PP == domain 2 score: 308.2 bits; conditional E-value: 2.6e-95 TPR_Epg5 1 nqpseclrlleliLknprlaelLaphFtPnavspseflqlYeevvsalrkdssdvvfvLLskfDikkwlsslqpklsersrLlelifkaLaslg 94 n+ps++++ll++iL+ ++++ lL+p+F+Pn p+ f ++Y++++++ ++d++f+LL+kf+++kwlss + +l ers L +++f+aL ++ FUN_001787-T1 1800 NNPSQTEQLLSAILEFSSVSMLLVPFFSPNDN-PDAFTTMYRRILEST---NNDLIFALLTKFELPKWLSSQSSSLIERSSLTSAVFEALNGVD 1889 699*****************************.***********7755...99***************************************** PP TPR_Epg5 95 lepdeellmlfelfrkHlvhlleyqFPehygdvLrllLkgsseqklspsvwkdilnalgcktleeesssksleelrqfaqsqkllslqqvketi 188 ep e+++++ ++ +Hl+ +l y+FPe+y+d Lrll +gss+ +l+ +vw+ +l ++gc +++e+ +q+++s+ l +qv et+ FUN_001787-T1 1890 YEPAEDKKLILGVYLRHLTIMLVYNFPEQYSDSLRLLCEGSSKRSLCLDVWDRFLTCIGCVPTSEN---------QQESSSKEFLGDEQVLETL 1974 ***************************************************************997.........568899************* PP TPR_Epg5 189 ellsehfkkeRls..dlgsfgLYskwkpYveelallleyllhslvsselstlseepgslaekaleklfesivelfspwlepleeeedsksvllP 280 +l+++f+ +R + + + gLY++w+pY+++l+lll+++++ +v+ ++ + ++g+ ++ l +l++ i+++f+pw++ ++ + ++P FUN_001787-T1 1975 VWLTKYFSGQRAElgGHVTGGLYTMWRPYIKQLSLLLGFMCQQIVVRRAAVVFGNSGEGLDAVLTELWTLICRVFEPWICAQDSPIPGNDPVAP 2068 *************99999**********************************9******************************99999****** PP TPR_Epg5 281 WlesDaelAkkmvklfvelleflhesfkdellpgsenilslvwqyYveklaakkvkehvlsvihselvkLpWerfhPdladlelmlkvleqslp 374 W+es+ ++A+ mv+lf+++l +l+++ + + +s+++++++w+++v++la+++v+e+vl v+ +++ +LpW++f+P+l+ lelm+++ + ++ FUN_001787-T1 2069 WNESEVSQASDMVTLFTDTLGCLQTH--LNAPYSSTSTMNMFWSFFVTSLAKPGVPEFVLRVFNAKFYSLPWQNFLPTLHNLELMVQSYT-VCK 2159 ***********************966..57799******************************************************986.689 PP TPR_Epg5 375 echlflgeifvripW 389 ++++flg +f ++W FUN_001787-T1 2160 NSFKFLGLVFPLMDW 2174 9*********99999 PP >> TPR_Epg5_2 Epg5-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 136.9 0.1 1.6e-43 8.2e-40 8 175 .. 1340 1531 .. 1334 1533 .. 0.91 Alignments for each domain: == domain 1 score: 136.9 bits; conditional E-value: 1.6e-43 TPR_Epg5_2 8 wealyeeLakkpkttldqavKkaasklklnlsverLaiYRWaelalatpekdhpvlpLilQqffilllsrrksee...kkfcvgerffesssns 98 +++ + L+kkp t+d+++Kk+a++lkl++s L+iYRW+++a+ t+ +dhp lpLi+Q+ff l+l+r+ +++ ++ +vg rffe+ +s FUN_001787-T1 1340 TAEMGKRLLKKPDATVDSVLKKVAKTLKLSWSP-ALSIYRWSNQAMVTD-MDHPMLPLIWQRFFRLYLQRPVTQPglaERTGVGYRFFEG-HYS 1430 5677889************************97.5************86.********************99988899999*********.799 PP TPR_Epg5_2 99 sllkklkkklleeaekkaskae.......................skefkkelaklfkavslWLeeprlyepnlyllsdlpldy...llqlilq 166 s+lkk+k++l ++ e++ +++ k ++++la++++++ lWL+eprl++p+l+l +lp+ y +l+++l+ FUN_001787-T1 1431 STLKKMKERLKATSEHHR-SKSvetaadhdtltdtnsdiskqfeqTKVLHEKLAGFYQTLVLWLDEPRLHDPSLFL-ASLPPPYdapRLETLLK 1522 *********977777655.44479********************999***************************76.78888888899****** PP TPR_Epg5_2 167 gdkepWlef 175 ++epW ++ FUN_001787-T1 1523 AEMEPWNDL 1531 ******997 PP >> TPR_Epg5_C Epg5-like, C-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.1 0.0 3.5e-14 1.8e-10 9 182 .. 2403 2586 .. 2398 2595 .. 0.80 2 ! 5.9 0.0 0.0018 9.3 187 251 .. 2616 2680 .. 2608 2684 .. 0.81 Alignments for each domain: == domain 1 score: 41.1 bits; conditional E-value: 3.5e-14 TPR_Epg5_C 9 slLEstilhYfrkseekapsha.....psWkdllqrle.kslekld.lepllknrfllsLhllvlykleeletdgdkitflqdlvqlleelKts 95 s+LE i+++f+k +++ +h+ W+ ++ ++ l + + ++ ++ +l+L+ +l kl + e+ + + + d+v + +K FUN_001787-T1 2403 SVLETGIESFFAKHSSQYLMHSqanpdGGWEVIVPSVAvPELAQDEfVQECVRQGAILTLYTNILLKLSSCESPVQEMNIINDVVSWCNRIKLR 2496 79**********999998888877766789999998875444443324667888899************************************* PP TPR_Epg5_C 96 ektEsklalvWgliissgvq.ilkes...eavkkpLlvlarylqiastksegWgdglLgviGl.kkdavtnkrkvlarClacvifsllpess 182 + E+k+ l+W i+ v+ ++ ++ + k+L la +l + ++ ++glLg+iG+ kk++++ k++ + r l +++ +p++ FUN_001787-T1 2497 RESETKMPLLWHKILRLAVRqVYYATgplRDLAKQLSFLAASLHSLGED--KASSGLLGAIGFgKKSQLSVKFRFICRALEAFLLAQMPSNA 2586 ***************9887614443322245667777777777766554..4589*******97899************9988888777765 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0018 TPR_Epg5_C 187 pseeyesalreLksllankkfaDvkikivkavslieekalpklrevpelvckli.rlFyeesfltt 251 + e e+al +L+ l +nk++ + ++iv+a s+i + l +l e pe v+ l +lF +e+ l++ FUN_001787-T1 2616 STPEAEQALTNLEILRSNKHYVGLAAQIVQAHSFIAN-PLHSLIEGPEFVTTLAqQLFPNEKALVI 2680 566889*****************************95.5557777777777776258888887766 PP >> RA_2 RA like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 0.26 1.3e+03 19 53 .. 1349 1383 .. 1343 1392 .. 0.81 2 ? 9.6 0.0 0.00026 1.3 17 40 .. 2332 2355 .. 2319 2358 .. 0.83 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 0.26 RA_2 19 vdsattarevceklaeklglkdsegFsLyeslpdk 53 ++++t+ v++k+a+ l+l+ s s+y ++ FUN_001787-T1 1349 KKPDATVDSVLKKVAKTLKLSWSPALSIYRWSNQA 1383 56899***************999888888766655 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00026 RA_2 17 vevdsattarevceklaeklglkd 40 vd+a+ta+evc +++e+l+l + FUN_001787-T1 2332 SGVDPASTASEVCMMISEQLNLLN 2355 569*****************9965 PP >> DUF8137 Domain of unknown function (DUF8137) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.00025 1.3 27 81 .. 560 614 .. 556 625 .. 0.89 2 ? -0.7 0.1 0.19 1e+03 44 99 .. 799 854 .. 791 872 .. 0.76 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00025 DUF8137 27 dAvlqavaqyErelseaheaedsdtYrgifrafyepvvealdeaaqaegWefLad 81 +A+lq + + E l++ ++e ++t+r i+++f ++ eal++ + W ++++ FUN_001787-T1 560 AALLQPIREREGFLHKLSQREKDETFRSISWTFVDEDGEALEDEDPETSWMLIEE 614 68888899999999999*********************************99975 PP == domain 2 score: -0.7 bits; conditional E-value: 0.19 DUF8137 44 heaedsdtYrgifrafyepvvealdeaaqaegWefLadlld.AyepestddfPlvsp 99 +e+ +d++r+i ++ ++ ++ l + q+e +L+ + + A ++e++d++ l+ FUN_001787-T1 799 RENAYKDNWRDILESREGEFTDQLARISQSEAIFLLTTFANiATSREEEDKE-LIVA 854 34445699*******************************9944555555544.4433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (2688 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1135 (0.0444314); expected 510.9 (0.02) Passed bias filter: 795 (0.0311216); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.73u 0.42s 00:00:01.14 Elapsed: 00:00:00.44 # Mc/sec: 24492.18 // Query: FUN_001788-T1 [L=225] Description: FUN_001788 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-45 154.6 1.0 3.9e-45 154.0 1.0 1.2 1 Mesd Chaperone for wingless signalling and trafficking o ------ inclusion threshold ------ 0.29 11.7 3.4 0.18 12.3 1.0 1.9 2 ETRAMP Malarial early transcribed membrane protein (ETRAMP 0.45 11.5 3.5 0.74 10.8 3.5 1.3 1 LsmAD LsmAD domain Domain annotation for each model (and alignments): >> Mesd Chaperone for wingless signalling and trafficking of LDL receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 154.0 1.0 4.5e-49 3.9e-45 2 148 .. 71 222 .. 70 224 .. 0.88 Alignments for each domain: == domain 1 score: 154.0 bits; conditional E-value: 4.5e-49 Mesd 2 kdirdytdadlerlldqweeddeplee....delPehl..rkspkidlskldlsnPenllkltkkGktlmvfvtvsgdltrkeaeeitklwqtsll 91 k++ dy++ dl +lldqwe++de ++e d+l + rk + d +k++ ++P +l+kl+kkGk +m+f+tv+g++t+ e+e+i wq+sl+ FUN_001788-T1 71 KNVMDYNEGDLHKLLDQWEDNDEDIDEedkyDDLDPRKqsRKGFEFDPTKFK-DDPIALMKLSKKGKVVMLFATVAGNPTKTETEQISGRWQSSLF 165 899**********************882233445433311555566777775.68***************************************** PP Mesd 92 nnhiqaeryliddnraifmfkdGsqaweakdflveqerckevtlegksypGkkakkd 148 n+++q+eryl+ dnr++ m+kdGs aw++kdfl+ q+ c+ v e++++pG k + FUN_001788-T1 166 NAQFQIERYLVADNRVLLMIKDGSLAWDIKDFLITQPDCELVEFENQQFPGAGGKTK 222 ***************************************************987655 PP >> ETRAMP Malarial early transcribed membrane protein (ETRAMP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 1.0 2.1e-05 0.18 5 44 .. 31 73 .. 29 100 .. 0.82 2 ? -1.8 0.1 0.55 4.7e+03 45 58 .. 129 142 .. 120 146 .. 0.63 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.1e-05 ETRAMP 5 kvlalfaiLliinll.vpclcnnn..akkeknkkelkkidkkl 44 k+++lf +L++i +l +cl++++ +++k k++ kki k++ FUN_001788-T1 31 KFSLLFSVLFLIFILrESCLSEETkkTEPKKRKEKDKKIGKNV 73 8899*****9999999999999877766666666666666554 PP == domain 2 score: -1.8 bits; conditional E-value: 0.55 ETRAMP 45 ekkkkkkkiiiiSs 58 k kk k++++ + FUN_001788-T1 129 MKLSKKGKVVMLFA 142 45566667766544 PP >> LsmAD LsmAD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 3.5 8.7e-05 0.74 20 67 .. 56 101 .. 51 105 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 8.7e-05 LsmAD 20 speykereaeAeriArEIessasknahvaeerglkveddsgldEEdkY 67 + e k+r+++ ++i + ++ ++++ h + ++ ++d+++dEEdkY FUN_001788-T1 56 KTEPKKRKEKDKKIGKNVMDYNEGDLHKLLDQWE--DNDEDIDEEDKY 101 5678999************************999..56889******* PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (225 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1296 (0.050734); expected 510.9 (0.02) Passed bias filter: 728 (0.0284987); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2201.48 // Query: FUN_001789-T1 [L=402] Description: FUN_001789 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-30 106.6 0.0 3.2e-30 105.8 0.0 1.3 1 rva_4 Integrase core domain ------ inclusion threshold ------ 0.016 15.9 0.0 1.2 9.9 0.0 3.1 3 DUF6074 Family of unknown function (DUF6074) 0.14 12.9 0.0 0.37 11.6 0.0 1.7 1 rve Integrase core domain 6.6 7.5 6.1 1.3 9.8 0.2 2.7 3 HTH_21 HTH-like domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 105.8 0.0 5e-34 3.2e-30 2 173 .. 135 314 .. 134 320 .. 0.90 Alignments for each domain: == domain 1 score: 105.8 bits; conditional E-value: 5e-34 rva_4 2 ykvatPnslWhidgnmklirWrlvvhGaidgysrlivyleastnnrastvlkq.flkavkkyglPsrv.rsdkggenvkvallmnllrGler.... 91 y+ + Pn l hidg k+ +++ vhGaidgysr i++le+s++n+ ++++ +l+ v++ g srv r+d+g+e ++a + + +r l+r FUN_001789-T1 135 YSTKGPNYLRHIDGYDKIKPFGFCVHGAIDGYSRKILWLEVSSSNNDPGIITKyYLDYVRQIGGTSRViRADRGTEDGNIAVTQQFFRRLARddfg 230 88999************************************99998888876526899********966************999999887763333 PP rva_4 92 ..ssvitGrsvhnqrierlWrdvfkkvvsvfyslftaledseildidndihllalhivylpriqkeleefknawnnhklrtekn 173 +s++ Grs nqrie W + k++ + + + f+ l d +++ d+ +h+ +l++ ++ +q el++ + wn+h +r n FUN_001789-T1 231 aeKSFMYGRSTANQRIEAWWGILRKQCSDWWIKYFKDLRDAGLFCDDDIVHRECLKFCFMDLLQMELHKIARLWNTHRIRPSAN 314 33689****************************************9*********************************97654 PP >> DUF6074 Family of unknown function (DUF6074) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00018 1.2 39 73 .. 48 82 .. 41 100 .. 0.86 2 ? -0.3 0.0 0.28 1.8e+03 43 74 .. 264 299 .. 254 307 .. 0.77 3 ? 1.3 0.0 0.087 5.6e+02 40 60 .. 331 351 .. 319 356 .. 0.85 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00018 DUF6074 39 ecralaaeLarlGlseeeireevlaFqdaVqaele 73 ++r+l++ L+++G+++ e+ + + +aV+ el+ FUN_001789-T1 48 SLRQLRRILKNRGCTRREQSTDMGIIVRAVEGELR 82 789******************************98 PP == domain 2 score: -0.3 bits; conditional E-value: 0.28 DUF6074 43 laaeLarlG..lseeeireevlaF..qdaVqaeler 74 ++++L+++G ++++ +++e l+F +d q+el++ FUN_001789-T1 264 YFKDLRDAGlfCDDDIVHRECLKFcfMDLLQMELHK 299 688999999656888899999985336777777765 PP == domain 3 score: 1.3 bits; conditional E-value: 0.087 DUF6074 40 cralaaeLarlGlseeeiree 60 ++ ++ L+++G++e +i+ee FUN_001789-T1 331 ANHTRDYLTQVGVDEVDIAEE 351 5677889***********998 PP >> rve Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 5.7e-05 0.37 4 78 .. 140 211 .. 137 226 .. 0.79 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 5.7e-05 rve 4 pnqlwqgDit.yikvpgkggklyllvivDdfsreivawalsse.msaetvlaalekaiakrggvkpkiihsDngsef 78 pn+l ++D +ik g ++++ ++D +sr+i+ +ss+ ++ +++ +++ gg ++i+ D+g+e FUN_001789-T1 140 PNYLRHIDGYdKIK--PFG--FCVHGAIDGYSRKILWLEVSSSnNDPGIITKYYLDYVRQIGGT-SRVIRADRGTED 211 77777888776666..345..79*****************999455567778888899999997.699999999885 PP >> HTH_21 HTH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.3 0.44 2.8e+03 33 52 .. 42 61 .. 35 65 .. 0.77 2 ? 9.8 0.2 0.00021 1.3 17 50 .. 84 117 .. 72 128 .. 0.87 3 ? -1.7 0.1 0.78 5e+03 31 52 .. 298 309 .. 293 311 .. 0.49 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.44 HTH_21 33 eggirvnrkrVaRLMrelgL 52 +gir + ++ +R+ + g FUN_001789-T1 42 VHGIRLSLRQLRRILKNRGC 61 45899999999999998886 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00021 HTH_21 17 srgtYGyRritaeLrreggirvnrkrVaRLMrel 50 s + GyR ++ L ++++ v r+ V+ + l FUN_001789-T1 84 SGSIIGYRSMHQRLTTDHQLIVTRNIVRQVIKIL 117 66789**********************9988876 PP == domain 3 score: -1.7 bits; conditional E-value: 0.78 HTH_21 31 rreggirvnrkrVaRLMrelgL 52 + ++aRL + + + FUN_001789-T1 298 H----------KIARLWNTHRI 309 2..........44444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 613 (0.0239969); expected 510.9 (0.02) Passed bias filter: 581 (0.0227442); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 4033.52 // Query: FUN_001790-T1 [L=255] Description: FUN_001790 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 16.5 0.0 4.8 8.2 0.0 2.3 2 DUF7738 Domain of unknown function (DUF7738) 0.049 13.9 0.1 14 5.9 0.0 2.2 2 PDZ_3 PDZ domain 0.07 14.1 45.7 33 5.5 18.6 4.1 2 UPAR_LY6 u-PAR/Ly-6 domain 0.13 13.1 6.9 4.8 8.1 0.2 2.9 4 PriCT_2 Primase C terminal 2 (PriCT-2) 0.15 12.5 0.0 2.7 8.4 0.0 2.1 2 WbmS-like Polysaccharide deacetylase 0.33 11.1 10.5 5.6 7.2 1.8 3.3 2 CFAI_FIMAC_N Complement factor I, FIMAC N-terminal domain Domain annotation for each model (and alignments): >> DUF7738 Domain of unknown function (DUF7738) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.0011 4.8 58 98 .. 43 82 .. 33 86 .. 0.81 2 ? 6.0 0.0 0.0054 23 58 98 .. 147 186 .. 139 190 .. 0.82 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0011 DUF7738 58 kvveelsiyenkkkeelefapkklFkGkltvdgkeidkktk 98 +++ si ++++ +ef +++ F+ +lt +g+++d+ k FUN_001790-T1 43 TKIYDCSIV-DPERDPSEFRCTEVFTSQLTKNGQQLDNFAK 82 333355566.79999*********************98776 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0054 DUF7738 58 kvveelsiyenkkkeelefapkklFkGkltvdgkeidkktk 98 ++++ si +++ +ef +++ F+ +lt +g+++d+ k FUN_001790-T1 147 TKISDCSIV-DPERPPSEFRCAEVFTSQLTKNGQQLDNFAK 186 455566666.78888999******************98776 PP >> PDZ_3 PDZ domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.0 0.0033 14 85 112 .. 72 99 .. 62 114 .. 0.82 2 ? 5.8 0.0 0.0035 15 85 112 .. 176 203 .. 167 218 .. 0.82 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0033 PDZ_3 85 vNgekvknlkhlvqlvekskeeflrfel 112 Ng+++ n++++++ +k+++e r e+ FUN_001790-T1 72 KNGQQLDNFAKFCTTWDKCDDERCRQEM 99 4*******************99877665 PP == domain 2 score: 5.8 bits; conditional E-value: 0.0035 PDZ_3 85 vNgekvknlkhlvqlvekskeeflrfel 112 Ng+++ n++++++ +k+++e r e+ FUN_001790-T1 176 KNGQQLDNFAKFCTTWDKCDDERCRQEM 203 4*******************99877665 PP >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 18.6 0.0078 33 2 81 .. 24 125 .. 23 126 .. 0.71 2 ? 5.4 19.1 0.0086 37 1 81 [. 127 229 .. 127 230 .. 0.69 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0078 UPAR_LY6 2 glrCysClgessssccssgs...sCpkgd..........tqCvtttiklsgg....gkksslsvkgC..spscpelnetseig...sltvtesccq 75 +lrC+ C++ +s+++c++ + C+ d t +t++++++g+ + k+ + +C + +++e+++++ ++ ++ cc+ FUN_001790-T1 24 SLRCHACYSAKSWDDCEKNTkiyDCSIVDperdpsefrcTEVFTSQLTKNGQqldnFAKFCTTWDKCddERCRQEMTKSGDKDvlkANYCDVECCS 119 69****************999**99666666788875553334444444444444478888888888*544445555555555776777889**** PP UPAR_LY6 76 sdlCns 81 +dlCn FUN_001790-T1 120 GDLCNG 125 *****5 PP == domain 2 score: 5.4 bits; conditional E-value: 0.0086 UPAR_LY6 1 qglrCysClgessssccssgs...sCpkgd..............tqCvtttiklsgggkksslsvkgC..spscpelnetseig...sltvtescc 74 ++lrC+ C++ +s+++c++ + C+ d t+ +t + ++ +++ k+ + +C + +++e+++++ ++ ++ cc FUN_001790-T1 127 NSLRCHACYSAKSWDDCEKNTkisDCSIVDperppsefrcaevfTSQLTKNGQQLDNFAKFCTTWDKCddERCRQEMTKSGDKDvlkANYCDVECC 222 589****************9999989665556777774443333444444444444477888888888*544445555555555776777889*** PP UPAR_LY6 75 qsdlCns 81 ++dlCn FUN_001790-T1 223 SGDLCNG 229 ******5 PP >> PriCT_2 Primase C terminal 2 (PriCT-2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 5.4 2.3e+04 56 65 .. 33 42 .. 28 45 .. 0.65 2 ? 8.1 0.2 0.0011 4.8 31 58 .. 71 98 .. 61 106 .. 0.86 3 ? -2.3 0.0 2 8.5e+03 56 69 .. 137 150 .. 130 155 .. 0.72 4 ? 8.1 0.2 0.0012 4.9 31 58 .. 175 202 .. 166 210 .. 0.85 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 5.4 PriCT_2 56 ekkWdsfkrg 65 +k+Wd ++++ FUN_001790-T1 33 AKSWDDCEKN 42 4667777644 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0011 PriCT_2 31 geagegldlwdewSkksekYksgecekk 58 ++g++ld + +++++++k++++ c+++ FUN_001790-T1 71 TKNGQQLDNFAKFCTTWDKCDDERCRQE 98 457899**************9999*986 PP == domain 3 score: -2.3 bits; conditional E-value: 2 PriCT_2 56 ekkWdsfkrgggvt 69 +k+Wd +++++++ FUN_001790-T1 137 AKSWDDCEKNTKIS 150 57888888766665 PP == domain 4 score: 8.1 bits; conditional E-value: 0.0012 PriCT_2 31 geagegldlwdewSkksekYksgecekk 58 ++g++ld + +++++++k++++ c+++ FUN_001790-T1 175 TKNGQQLDNFAKFCTTWDKCDDERCRQE 202 447899**************9999*986 PP >> WbmS-like Polysaccharide deacetylase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 0.0 0.00064 2.7 75 137 .. 16 77 .. 11 111 .. 0.76 2 ? 2.3 0.0 0.047 2e+02 77 135 .. 122 179 .. 98 214 .. 0.75 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.00064 WbmS-like 75 leivpeaksvRsHsLvqsssllallakeglkydvslfiplqkeitlkpferlggellripyfw 137 ++pe+ s+R H+ + + + +k+ yd+s + p+++ + + +e ++ +l++ + FUN_001790-T1 16 AVLLPEGYSLRCHACYSA-KSWDDCEKNTKIYDCSIVDPERDPSEFRCTEVFTSQLTKNGQQL 77 5689**********9877.777888888889********999989999988888877655544 PP == domain 2 score: 2.3 bits; conditional E-value: 0.047 WbmS-like 77 ivpeaksvRsHsLvqsssllallakeglkydvslfiplqkeitlkpferlggellripy 135 ++ + s+R H+ + + + +k+ +d+s + p+++ + + e ++ +l++ FUN_001790-T1 122 LCNGGNSLRCHACYSA-KSWDDCEKNTKISDCSIVDPERPPSEFRCAEVFTSQLTKNGQ 179 67778999***99877.6677777777789*******9998888888888777766544 PP >> CFAI_FIMAC_N Complement factor I, FIMAC N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 1.8 0.0013 5.6 9 21 .] 83 95 .. 82 95 .. 0.96 2 ? 7.2 1.8 0.0013 5.6 9 21 .] 187 199 .. 186 199 .. 0.96 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0013 CFAI_FIMAC_N 9 FCpPWqRCidGkC 21 FC W +C d++C FUN_001790-T1 83 FCTTWDKCDDERC 95 ********99999 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0013 CFAI_FIMAC_N 9 FCpPWqRCidGkC 21 FC W +C d++C FUN_001790-T1 187 FCTTWDKCDDERC 199 ********99999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (255 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 824 (0.0322568); expected 510.9 (0.02) Passed bias filter: 341 (0.013349); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2543.53 // Query: FUN_001791-T1 [L=406] Description: FUN_001791 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-22 79.7 0.1 6.2e-22 78.5 0.0 1.6 2 CUB CUB domain 0.00017 21.9 0.0 0.00041 20.6 0.0 1.7 1 CUB_2 CUB-like domain 0.0089 16.1 0.0 0.024 14.7 0.0 1.6 1 CDCP1_CUB_6 CDCP1 CUB domain Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.5 0.0 7.3e-26 6.2e-22 6 110 .] 10 114 .. 7 114 .. 0.92 2 ? -4.0 0.0 3 2.6e+04 86 101 .. 174 189 .. 170 191 .. 0.76 Alignments for each domain: == domain 1 score: 78.5 bits; conditional E-value: 7.3e-26 CUB 6 tessgsisspnypkeYeenkeCvweirvekgksvklkfedfeleeeeecaydyvevrdgeeasskllgkfcG..sekpediksssnqllikfvsde 99 ++ sg++ssp yp Y+ n++Cvwei+v+kg+ ++lkfe+f+l e++c d+v vrdg ++ sk l +cG + +++s ++ + ++fvsd+ FUN_001791-T1 10 NTLSGRFSSPGYPTGYPYNAKCVWEIKVPKGYLITLKFESFDLG-ESSC-ADHVVVRDGINSWSKKLMLVCGgqDITELVVSSFGSGMRVEFVSDK 103 5679***************************************9.7778.8*********************7444556778899*********** PP CUB 100 svskkGFkaty 110 ++s++GF a+y FUN_001791-T1 104 QISASGFLASY 114 *******9998 PP == domain 2 score: -4.0 bits; conditional E-value: 3 CUB 86 sssnqllikfvsdesv 101 ++sn+ ++f+ d+ + FUN_001791-T1 174 TRSNRQSVSFTEDDVI 189 5788888999988765 PP >> CUB_2 CUB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 4.8e-08 0.00041 35 62 .. 22 49 .. 10 99 .. 0.82 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 4.8e-08 CUB_2 35 lpkipanqnCsyninvPkgyyakvtisa 62 ++ +p n +C ++i+vPkgy ++++++ FUN_001791-T1 22 PTGYPYNAKCVWEIKVPKGYLITLKFES 49 667999*******************986 PP >> CDCP1_CUB_6 CDCP1 CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 2.8e-06 0.024 18 57 .. 16 57 .. 5 62 .. 0.85 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2.8e-06 CDCP1_CUB_6 18 LatPnwpeGmkpsstvsWivsvpskqkaelkfln..lsqpkC 57 + +P++p+G + ++ W ++vp+ + +lkf++ l + +C FUN_001791-T1 16 FSSPGYPTGYPYNAKCVWEIKVPKGYLITLKFESfdLGESSC 57 689*****************************9844456666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (406 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 863 (0.0337835); expected 510.9 (0.02) Passed bias filter: 719 (0.0281464); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 4077.77 // Query: FUN_001793-T1 [L=704] Description: FUN_001793 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-23 81.3 0.0 1.6e-22 80.4 0.0 1.5 1 CUB CUB domain 5.2e-15 56.4 0.2 5.2e-15 56.4 0.2 1.7 2 Laminin_G_3 Concanavalin A-like lectin/glucanases superfa 5.3e-06 26.8 0.0 2.2e-05 24.8 0.0 1.9 1 Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor b 2.9e-05 24.3 0.1 5.7e-05 23.4 0.1 1.4 1 Pentaxin Pentaxin family 8.7e-05 22.8 0.0 0.00024 21.4 0.0 1.7 1 CUB_2 CUB-like domain ------ inclusion threshold ------ 0.031 14.3 0.0 0.084 12.9 0.0 1.7 1 CDCP1_CUB_6 CDCP1 CUB domain Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.4 0.0 3.7e-26 1.6e-22 1 110 [] 273 382 .. 273 382 .. 0.94 Alignments for each domain: == domain 1 score: 80.4 bits; conditional E-value: 3.7e-26 CUB 1 CggeltessgsisspnypkeYeenkeCvweirvekgksvklkfedfeleeeeecaydyvevrdgeeasskllgkfcG..sekpediksssnqllik 94 Cg l++ sg++ssp yp Y+ n++Cvwei+v+kg+ ++lkfe f+l +++c d+v vrdg ++ sk + ++cG + +++s ++ + ++ FUN_001793-T1 273 CGLFLNTLSGRFSSPGYPTGYPYNAKCVWEIKVPKGYFITLKFEYFDLG-DSSC-ADHVLVRDGINSWSKKIMSVCGgqDVTKLVVSSFGSGMRVE 366 8889999*****************************************9.6677.8*********************6556667788999****** PP CUB 95 fvsdesvskkGFkaty 110 fvsd+++s++GF a+y FUN_001793-T1 367 FVSDKQISASGFLASY 382 ************9998 PP >> Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.2 1.2e-18 5.2e-15 7 151 .] 88 248 .. 82 248 .. 0.83 2 ? -2.5 0.2 1.7 7.2e+03 31 71 .. 629 669 .. 624 683 .. 0.45 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 1.2e-18 Laminin_G_3 7 vtlpd.aslt..tsafTvsaWvkpdsapqssralvs.essgg.........gyelgldsdgqlrftvnggngaee.avtsgasvpagqWtHvavty 88 + lp + l+ ++T+ +W+ + +s + s es+++ ++e++ +++ ++++ ++g++g++ +++++++ a++W + v y FUN_001793-T1 88 IHLPGsRHLNenMRSITILVWIFQTGHAGSIVNFNSnESNEDseaygrspvSVEIRTSGSSSISADLAGNDGRRVhLWSNSSEALANEWRYIGVSY 183 5565555554235699******999999977777767444447789999999999999999****999998877634456666667********** PP Laminin_G_3 89 d..ggtlrlYvnGeevgsstltgaltkatggplyiGrdnggdspfdGlidevriynraLsaeeia 151 d + ++ + ++Ge v+ ++ +l+ t+ +++iG+++g +++f G+i +++y+raLs +e++ FUN_001793-T1 184 DhsSREVIMWIDGEDVDHLSILKNLDLSTDRSIQIGGRQGKQDSFEGRISCLQVYDRALSKKEVK 248 *76677*********************************************************95 PP == domain 2 score: -2.5 bits; conditional E-value: 1.7 Laminin_G_3 31 pqssralvsessgggyelgl.dsdgqlrftvnggngaeeavt 71 ++++r+++ e+ g + +++l +++g ++ t++++ ++ ++v+ FUN_001793-T1 629 GNQTRIVI-EDRGSHASVTLrENSGVIETTIASNRNSATSVQ 669 33445555.444445566653455555555555543333333 PP >> Toxin_R_bind_N Clostridium neurotoxin, N-terminal receptor binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 5.2e-09 2.2e-05 4 180 .] 50 242 .. 48 242 .. 0.73 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 5.2e-09 Toxin_R_bind_N 4 ikDaSgknskievsedielvy...innnalklknseqsisfsnkilensltnnFsisfWlripkkdnseskiIsskknn.......sGWkvslen 88 DaS ++++ + +d+elv ++ a + + i+++ + n+ + + +i W+ +++ s + s+ +n+ s +v ++ FUN_001793-T1 50 TADASCYGNLHGMPQDVELVGgpfHKQRAAYQFTGTSCIHLPGSRHLNENMRSITILVWIFQTGHAGSIVNFNSNESNEdseaygrSPVSVEIRT 144 579999999999999999997653233333334445699999999999999********999888877444444443335555444445666665 PP Toxin_R_bind_N 89 neliftlidsngne.kkivl....sdyi.nkWvfitisndrlknklliyingklvanesiknllniyssnnIslklvrcadenksvlieelsifn 177 + d +gn +++ l s+ + n+W +i +s d+++ ++ ++i+g+ v++ si + l + ++ I++ + +++ + i l++++ FUN_001793-T1 145 SGSSSISADLAGNDgRRVHLwsnsSEALaNEWRYIGVSYDHSSREVIMWIDGEDVDHLSILKNLDLSTDRSIQIGGRQGKQDSFEGRISCLQVYD 239 55444444555543245555889855556*******************************99899999999998777777788888999999999 PP Toxin_R_bind_N 178 kel 180 ++l FUN_001793-T1 240 RAL 242 875 PP >> Pentaxin Pentaxin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.1 1.4e-08 5.7e-05 82 168 .. 173 252 .. 160 259 .. 0.89 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 1.4e-08 Pentaxin 82 avepvhiCasWesssGivelwvdGkplvkkslkkgytvgaeasiilGqeqDsyGGkfdksqslvGelsdlnlWdyvLspeeiktvyk 168 a e+++i +s++ ss +v +w+dG+ + + s k+ + ++ si +GG k+ s++G +s l+++d +Ls++e+k v + FUN_001793-T1 173 ANEWRYIGVSYDHSSREVIMWIDGEDVDHLSILKNLDLSTDRSIQ-------IGGRQGKQDSFEGRISCLQVYDRALSKKEVKAVRN 252 459****************************************95.......567778999*********************99865 PP >> CUB_2 CUB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.0 5.5e-08 0.00024 35 62 .. 290 317 .. 281 344 .. 0.83 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 5.5e-08 CUB_2 35 lpkipanqnCsyninvPkgyyakvtisa 62 ++ +p n +C ++i+vPkgy++++++++ FUN_001793-T1 290 PTGYPYNAKCVWEIKVPKGYFITLKFEY 317 567999*******************986 PP >> CDCP1_CUB_6 CDCP1 CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 2e-05 0.084 18 51 .. 284 317 .. 277 329 .. 0.85 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 2e-05 CDCP1_CUB_6 18 LatPnwpeGmkpsstvsWivsvpskqkaelkfln 51 + +P++p+G + ++ W ++vp+ + +lkf+ FUN_001793-T1 284 FSSPGYPTGYPYNAKCVWEIKVPKGYFITLKFEY 317 679****************************985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (704 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 688 (0.0269329); expected 510.9 (0.02) Passed bias filter: 562 (0.0220004); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 6811.10 // Query: FUN_001794-T1 [L=509] Description: FUN_001794 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-113 378.5 0.0 7.4e-113 378.2 0.0 1.0 1 p450 Cytochrome P450 Domain annotation for each model (and alignments): >> p450 Cytochrome P450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 378.2 0.0 2.9e-117 7.4e-113 2 446 .. 47 490 .. 46 506 .. 0.89 Alignments for each domain: == domain 1 score: 378.2 bits; conditional E-value: 2.9e-117 p450 2 pgptplplvgnllqlek.keelhsvltklqkkygpifrlkl.gskpvvvlsgpelvkevlikkgeefsgrpdealletlskafkgkgvlfangekw 95 pgptplp++gn+l + ++ lh ++++++kyg++f+++l gs+p++v+ + e+vk+v++k+ ++f +rp + ++ k +++a+g++w FUN_001794-T1 47 PGPTPLPFIGNMLDSMRyRGLLHVQFKDYHEKYGNVFGMYLfGSTPTLVVADLEMVKQVYVKDFHSFRDRPVLLKFP----DPLDKMLTVAQGDEW 138 89************9999********************996589*******************88888876666666....59************* PP p450 96 rklRrlltptltsfgkl.sleeiveeeardlveklrkkagesselditellskaalnvicsilFgerfdlledekfsellkaveelsellssssvq 190 +++R++ltpt+ + k+ ++++++++ ++l++k+++ + + +++di l++ +++vi +++Fg++ d+ ++++++ + +a + + s+s++ FUN_001794-T1 139 KRIRSTLTPTFSAH-KMkQMVPLMNSACDMLMKKFDEISCKGESFDILSLFQGLTMDVILQCAFGIQADTQNNPDEPAITAAKRVI---NGSPSQR 230 **************.8889*******************999999*************************99999887766666666...5788888 PP p450 191 lldlfpllkylptkllkklkeavkklkdlldklieerretldsa.....kkkrrdfldalllakkekkge..sklsdeelkatvlellfaGvdTts 279 ll+ + l+++ +k + + ++ +d +l+ r+ ++ + ++r+d+ld++l a ++++ + + lsd e+ a+ +l+aG++T+s FUN_001794-T1 231 LLLSILSLLPFGNKVMEAFPSILTGDMD---ELLGISRQIVSAKksagsCESRKDLLDLMLMAAQDESLPksKRLSDSEVLAQSVIFLIAGYETSS 323 888888899*******999988544444...444444444444444477559*******999995555556899********************** PP p450 280 stlswaLyeLaknPevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtlvivnlyalhrdp 374 +tl ++ y+La+nP+vq+kl++Eid+v +++ p+y++++ lpyld+vi EtLR++p+++ ++R++t+++ +++ ++pkG v +++y+lh+d FUN_001794-T1 324 NTLGIVAYFLATNPDVQKKLQKEIDSVWdDESKMPSYETVNGLPYLDMVISETLRIYPPAV-ATMRTCTENCMLKDLKVPKGLVVTIPIYSLHMDS 418 ****************************77778****************************.999******************************* PP p450 375 kvfpnPeeFdpeRFldekgnsrksfaflPFGaGpRnClGerlArmelklflatlLqnFevelqpetdpkdid 446 k++pnPe+FdpeRF +e ++sr+++ + PFG Gp+nC+G+r+A+me+kl+la++L++++++ ++t++++ FUN_001794-T1 419 KFWPNPEKFDPERFTPEAKQSRDPYVYQPFGHGPHNCVGMRFAQMEMKLVLARILKKYSFQAAQDTKIPPEI 490 *******************88****************************************99888887754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (509 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 704 (0.0275592); expected 510.9 (0.02) Passed bias filter: 654 (0.0256019); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4935.52 // Query: FUN_001794-T2 [L=386] Description: FUN_001794 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-67 227.6 0.0 4.3e-67 227.4 0.0 1.0 1 p450 Cytochrome P450 ------ inclusion threshold ------ 0.22 11.9 0.0 0.41 11.1 0.0 1.4 1 TPK_catalytic Thiamin pyrophosphokinase, catalytic domain Domain annotation for each model (and alignments): >> p450 Cytochrome P450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 227.4 0.0 3.4e-71 4.3e-67 2 338 .. 47 383 .. 46 385 .. 0.86 Alignments for each domain: == domain 1 score: 227.4 bits; conditional E-value: 3.4e-71 p450 2 pgptplplvgnllqlek.keelhsvltklqkkygpifrlkl.gskpvvvlsgpelvkevlikkgeefsgrpdealletlskafkgkgvlfangekw 95 pgptplp++gn+l + ++ +h +++++kkyg++f+l++ gs+p++v+ + e+vk+v++k+ ++f +rp + ++ k +++a+g++w FUN_001794-T2 47 PGPTPLPFIGNMLDSMRyRGLVHVQFEDYHKKYGNVFGLYIfGSTPALVVADLEMVKQVYVKDFHSFRDRPVLLKFP----DPLDKMLTVAQGDEW 138 89************9999*********************95499*******************88888876666666....59************* PP p450 96 rklRrlltptltsfgkl.sleeiveeeardlveklrkkagesselditellskaalnvicsilFgerfdlledekfsellkaveelsellssssvq 190 +++R++ltpt+ + k+ ++++++++ ++l++k+++ + + +++di l++ ++++vi +++Fg++ d+ ++++++ + +a + ++ + s+ FUN_001794-T2 139 KRIRSTLTPTFSAH-KMkQMVPLMNSACDMLMKKFDEISCKEESFDILSLFQGITMDVILQCAFGVQADTQNNPDEPAITAAKRVINGSA--SRRL 231 **************.8889******************9999999*************************999998877777777775333..3334 PP p450 191 lldlfpllkylptkllkklkeavkklkdlldklieerretldsa.....kkkrrdfldalllakkekkge..sklsdeelkatvlellfaGvdTts 279 l+ + + l+++ +k + + ++ + +d l + r+ ++ + ++r+dfld++l a ++++ + + lsd e+ a+ +l+aG++T+s FUN_001794-T2 232 LISILS-LLPFGNKVMEAFPSILMGDMDEL---LGISRQIVSAKksgrsCDSRKDFLDLMLMAAQDESLPksKRLSDSEVLAQSVIFLIAGYETSS 323 555555.77999999999997754433333...3333333333333355449*******999995555556899********************** PP p450 280 stlswaLyeLaknPevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvv 338 +tl ++ y+La+nP+vqekl++Eid+v +++ p+y++++ lpyld+vi EtLR++p+ FUN_001794-T2 324 NTLGFVAYFLATNPDVQEKLQKEIDSVWdDESKMPSYETVNGLPYLDMVISETLRMYPPG 383 ****************************77778*************************96 PP >> TPK_catalytic Thiamin pyrophosphokinase, catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 3.2e-05 0.41 22 70 .. 232 290 .. 217 327 .. 0.81 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 3.2e-05 TPK_catalytic 22 y..........keelgikpdvivGDlDSireevkeyykskgvkiiktpdqdstDlekai 70 + ++ ++ p++++GD+D + ++ +++k++ ++ +d+ Dl+++ FUN_001794-T2 232 LisilsllpfgNKVMEAFPSILMGDMDELLGISRQIVSAKKSGRSCDSRKDFLDLMLMA 290 466666667777788999*********************999999999*******9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (386 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 715 (0.0279898); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3728.36 // Query: FUN_001795-T1 [L=115] Description: FUN_001795 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.096 13.4 0.1 0.17 12.6 0.1 1.4 1 DUF6728 Family of unknown function (DUF6728) Domain annotation for each model (and alignments): >> DUF6728 Family of unknown function (DUF6728) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 6.8e-06 0.17 28 44 .. 87 103 .. 80 111 .. 0.84 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 6.8e-06 DUF6728 28 kmMHgiNkiSilmFlia 44 ++ H iN iSi +F+i FUN_001795-T1 87 RTNHSINSISISIFIIF 103 667***********985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 473 (0.0185163); expected 510.9 (0.02) Passed bias filter: 255 (0.00998238); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.20u 0.43s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1179.05 // Query: FUN_001797-T1 [L=309] Description: FUN_001797 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00075 20.6 1.3 0.0074 17.4 0.0 2.7 3 WBP-1 WW domain-binding protein 1 ------ inclusion threshold ------ 0.014 16.1 0.0 0.03 15.0 0.0 1.5 1 DUF7261 Family of unknown function (DUF7261) Domain annotation for each model (and alignments): >> WBP-1 WW domain-binding protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 5.8e-07 0.0074 20 99 .. 31 105 .. 21 108 .. 0.62 2 ? 0.2 0.2 0.13 1.7e+03 66 101 .. 130 171 .. 106 172 .. 0.51 3 ? -0.5 0.0 0.22 2.8e+03 37 63 .. 190 224 .. 175 243 .. 0.52 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 5.8e-07 WBP-1 20 ElwlfwlvwtllillsCccalakrraelrleqqrrereinlvayreaknaaslpldarllasaklPsyeevaarpetPpP 99 E+ + ++ ++ ++l+ C ++ + r+++r++ +r++ + a++ +++ + + l ++ +Psy++v+++p+ pP FUN_001797-T1 31 EVGVIVIGFCCICLVACALVILQLRSNNRRNTSSRRQRGTENAGEASQDR-----TRGALDAEAPPSYDAVIRSPHLYPP 105 44455555666666777666666666666655555444333333323333.....3467999*********999876665 PP == domain 2 score: 0.2 bits; conditional E-value: 0.13 WBP-1 66 aknaaslpldarllasaklPsyeevaar......petPpPpy 101 + n+a++ + r l+++++ ++ +++ r e PpP+y FUN_001797-T1 130 SVNSAHVNSHRRELSENNMAQHSNIQPRrssvgeTEDPPPAY 171 444455555555566555555555532223333356788887 PP == domain 3 score: -0.5 bits; conditional E-value: 0.22 WBP-1 37 ccalak.....rrae..lrleqqrrer.einlvay 63 cc+ a+ r+e r+++q+ + e+++ + FUN_001797-T1 190 CCVHAQspvegSRNEipGRVNAQNLSIsERTTERS 224 44443335555222244556666555433333333 PP >> DUF7261 Family of unknown function (DUF7261) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 2.3e-06 0.03 15 107 .. 40 135 .. 34 156 .. 0.74 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.3e-06 DUF7261 15 vAvaLvpvvlaylqlgyaadvaaageedapledaeraleraveea.aaevtgayawaereaav..eavrdaldadvdrletsraeegvvvrvtyna 107 +++Lv+ +l++lql++++ +++++++++ +e+a +a ++ ++ a ae++ +y+ r+ r++l+ dv++ ++s+a ++ +++v+ + FUN_001797-T1 40 CCICLVACALVILQLRSNNRRNTSSRRQRGTENAGEASQDRTRGAlDAEAPPSYDAVIRSPHLypPSRRTSLTLDVSETRRSSASSSCSLSVNSAH 135 69*********************9999888888877766555544156678888877666544115677888888888888888888887777654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (309 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 975 (0.0381679); expected 510.9 (0.02) Passed bias filter: 561 (0.0219612); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3099.58 // Query: FUN_001798-T1 [L=126] Description: FUN_001798 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.028 15.3 0.1 0.034 15.1 0.1 1.2 1 Anillin Cell division protein anillin 0.069 13.6 0.1 0.1 13.0 0.1 1.3 1 DUF8032 Domain of unknown function (DUF8032) Domain annotation for each model (and alignments): >> Anillin Cell division protein anillin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.1 2.7e-06 0.034 71 131 .. 25 85 .. 6 92 .. 0.74 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 2.7e-06 Anillin 71 dvppdFeidvevYslraleeklslsstpkklksklssskslsrspgkksav.rtskFkllGs 131 +p++F ++++vY al+++ + + t+k+ +++l + s + +++k + + +t ++k G+ FUN_001798-T1 25 SIPAQFALEMTVYT-IALKKQKQKKTTKKTKQKTLERALSYRGNVTKALVTlMTISYKSRGT 85 6899**********.58888888889999888888884444444443333366667776665 PP >> DUF8032 Domain of unknown function (DUF8032) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 8.2e-06 0.1 21 60 .. 16 55 .. 7 65 .. 0.82 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 8.2e-06 DUF8032 21 idiesvdleeideeFkkencvypralvekeeykgnrweye 60 +d +sv+ ++i+++F e vy al ++++ k+++ ++ FUN_001798-T1 16 FDFNSVNGDSIPAQFALEMTVYTIALKKQKQKKTTKKTKQ 55 6889*******************99987777666655443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2320 (0.0908201); expected 510.9 (0.02) Passed bias filter: 1084 (0.0424349); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1234.35 // Query: FUN_001799-T1 [L=369] Description: FUN_001799 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-14 52.8 0.1 3e-13 50.3 0.1 2.2 2 Arylesterase Arylesterase ------ inclusion threshold ------ 0.043 13.9 0.0 0.11 12.6 0.0 1.7 2 SGL SMP-30/Gluconolactonase/LRE-like region Domain annotation for each model (and alignments): >> Arylesterase Arylesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.3 0.1 2.3e-17 3e-13 2 84 .. 168 253 .. 167 255 .. 0.84 2 ? -0.6 0.0 0.18 2.3e+03 33 72 .. 295 335 .. 281 341 .. 0.83 Alignments for each domain: == domain 1 score: 50.3 bits; conditional E-value: 2.3e-17 Arylesterase 2 DivavGpdsfyatndhyF..gdnfllllemsl..qlawtavvYyspsevkvvasglssanGInidadkkyiyvadilresihvmkkh 84 + a+Gpdsfy+tnd++F g++ l ll ++l + +++vY+++++ v+ sg+ anGIn+d d+++i+ + ++ +s+ v++++ FUN_001799-T1 168 NLYAIGPDSFYVTNDNFFngGNKLLWLLHFYLlqDVLRGNIVYFDGKKSMVATSGI-NANGINMDKDERFIFASTSIGRSVKVFRRR 253 5679**************44466777888887446789*********988888776.69******************9999888765 PP == domain 2 score: -0.6 bits; conditional E-value: 0.18 Arylesterase 33 lawtavvYyspsevkvvasglssanGIni.dadkkyiyvad 72 l+ t+v + sps+v +v g s G+ + d + + +yv d FUN_001799-T1 295 LHSTNVSHPSPSQVFEVKLGKPSTSGVAFpDYEVREVYVND 335 67889999999999999999999999987567788888876 PP >> SGL SMP-30/Gluconolactonase/LRE-like region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.086 1.1e+03 157 178 .. 139 160 .. 23 185 .. 0.70 2 ? 12.6 0.0 8.7e-06 0.11 87 242 .. 165 333 .. 129 335 .. 0.66 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.086 SGL 157 kiyafdydaeggelsnrrvfad 178 + fd+d ++ l rr ++d FUN_001799-T1 139 VVEIFDFDRQTHSLIHRRSVID 160 3555666666666666666654 PP == domain 2 score: 12.6 bits; conditional E-value: 8.7e-06 SGL 87 rfNDgkvdpdGrlwaGtmaddeakgkee.............galyrldpdgklerlldgltisNGlawspDgktlYlaDslarkiyafdydaegge 169 ++N + +++++ ++++ ++k g+++++d++ ++++ + +NG+++++D++ ++ + s r++ +f ++++ FUN_001799-T1 165 SPNNLYAIGPDSFYVTNDNFFNGGNKLLwllhfyllqdvlrGNIVYFDGK--KSMVATSGINANGINMDKDERFIFASTSIGRSVKVFRRR-QDNT 257 55555555555666666666665555446777777766677888888777..44555556679**************************96.5555 PP SGL 170 lsnrrvfadfkkgegepDGlavDa.eGgvwvAlw........gggkvvrfdpdGklleeielPakrptscaFgGpdlrtLyv 242 l+ + + f ++++D + vD +G+ w + ++ +v + +p+ + e++l + ++ +aF + r+ yv FUN_001799-T1 258 LELSQEI-YF---DSYIDNINVDPlTGNFWLVGIprvtdailHSTNVSHPSPS--QVFEVKLGKPSTSGVAFPDYEVREVYV 333 7766655.23...3458999999999999986654544443344444444444..366677776677777777777666666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (369 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 490 (0.0191818); expected 510.9 (0.02) Passed bias filter: 443 (0.0173419); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3663.10 // Query: FUN_001800-T1 [L=340] Description: FUN_001800 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.017 15.8 0.1 0.043 14.5 0.1 1.7 1 GST_C_3 Glutathione S-transferase, C-terminal domain Domain annotation for each model (and alignments): >> GST_C_3 Glutathione S-transferase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.1 1.7e-06 0.043 25 66 .. 292 333 .. 275 338 .. 0.82 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.7e-06 GST_C_3 25 kfkeerlpkflkyfekvlkkngggylvgdklTyADlalfqvl 66 + ++ ++k+l++fe++l++ +++ l+ + lT D a++ ++ FUN_001800-T1 292 EQQKALVKKYLGWFENLLADDKKKILLDEPLTRSDCAFLRSF 333 3568889******************************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (340 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 732 (0.0286553); expected 510.9 (0.02) Passed bias filter: 447 (0.0174985); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3408.21 // Query: FUN_001801-T1 [L=407] Description: FUN_001801 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.022 14.6 0.0 0.059 13.2 0.0 1.6 2 Bact_GSDM Bacterial Gasdermin Family Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 0.23 5.9e+03 6 19 .. 28 41 .. 27 45 .. 0.84 2 ? 13.2 0.0 2.3e-06 0.059 106 163 .. 134 186 .. 123 213 .. 0.68 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.23 Bact_GSDM 6 arikPLqlllrkgs 19 + +kPL+l+ ++++ FUN_001801-T1 28 ETVKPLSLIFKRKR 41 6799*****99987 PP == domain 2 score: 13.2 bits; conditional E-value: 2.3e-06 Bact_GSDM 106 eLgnyLkaadidvdnpslgllkklkkgelyvitsvlksksfsvtaedengisveldvp 163 +L +L++a +d d++ ++++l++itsv++s++f+v e+ ++i++e ++ FUN_001801-T1 134 DLRGILSSAVLDADKMI-----PYQDQDLFLITSVVYSEKFEVVDERVRKIEFEGGLK 186 55556666666333333.....345788****************99999999887766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (407 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 940 (0.0367978); expected 510.9 (0.02) Passed bias filter: 675 (0.026424); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.42s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 3969.88 // Query: FUN_001801-T2 [L=411] Description: FUN_001801 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.035 14.0 0.0 0.08 12.8 0.0 1.6 1 Bact_GSDM Bacterial Gasdermin Family 0.063 14.2 0.0 0.14 13.0 0.0 1.5 1 DUF5638 Family of unknown function (DUF5638) Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 6.3e-06 0.08 127 176 .. 150 198 .. 124 215 .. 0.75 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 6.3e-06 Bact_GSDM 127 kklkkgelyvitsvlksksfsvtaedengisveldvpeiqeivggkvtvk 176 +++el++ tsv++s+sf+v e+++ ++e +v+ + +++ ++k FUN_001801-T2 150 TAYQDHELLLMTSVVYSESFEVVDERKQTVEFECSVE-LPMELSEVLKSK 198 445679***************************9999.444444444444 PP >> DUF5638 Family of unknown function (DUF5638) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 1.1e-05 0.14 29 82 .. 301 354 .. 292 367 .. 0.88 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.1e-05 DUF5638 29 lkqelkeiktyYnkafektesekaqeeiveeYeelilllkqvksgeisadeale 82 q++++i+ Y++ t+s ++q+++v++Y ++ +l + +is++e l FUN_001801-T2 301 TDQDMRNIERIYKNVLMTTNSREQQKALVKKYLGWFEELLTADKMKISLNEPLT 354 568899******************************************999765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (411 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1077 (0.0421609); expected 510.9 (0.02) Passed bias filter: 772 (0.0302212); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4033.56 // Query: FUN_001801-T3 [L=411] Description: FUN_001801 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 Bact_GSDM Bacterial Gasdermin Family 0.16 12.7 0.0 0.35 11.6 0.0 1.5 1 GST_C_3 Glutathione S-transferase, C-terminal domain Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 6.3e-06 0.08 127 176 .. 150 198 .. 124 215 .. 0.75 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 6.3e-06 Bact_GSDM 127 kklkkgelyvitsvlksksfsvtaedengisveldvpeiqeivggkvtvk 176 +++el++ tsv++s+sf+v e+++ ++e +v+ + +++ ++k FUN_001801-T3 150 TAYQDHELLLMTSVVYSESFEVVDERKQTVEFECSVE-LPMELSEVLKSK 198 445679***************************9999.444444444444 PP >> GST_C_3 Glutathione S-transferase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 2.8e-05 0.35 26 66 .. 324 364 .. 305 380 .. 0.82 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2.8e-05 GST_C_3 26 fkeerlpkflkyfekvlkkngggylvgdklTyADlalfqvl 66 ++ ++k+l++fe++l++ + + l+ + lT D ++ +l FUN_001801-T3 324 QQKALVKKYLGWFENLLADDKMKILLKEPLTRNDCLFLRSL 364 467889****************************9998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (411 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1051 (0.0411431); expected 510.9 (0.02) Passed bias filter: 780 (0.0305344); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.38u 0.37s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 3980.98 // Query: FUN_001803-T1 [L=68] Description: FUN_001803 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (68 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 271 (0.0106087); expected 510.9 (0.02) Passed bias filter: 185 (0.00724212); expected 510.9 (0.02) Passed Vit filter: 11 (0.000430613); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.22u 0.43s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 694.88 // Query: FUN_001805-T1 [L=141] Description: FUN_001805 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (141 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 336 (0.0131533); expected 510.9 (0.02) Passed bias filter: 268 (0.0104913); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1440.88 // Query: FUN_001806-T1 [L=154] Description: FUN_001806 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (154 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 913 (0.0357408); expected 510.9 (0.02) Passed bias filter: 676 (0.0264631); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1549.57 // Query: FUN_001807-T1 [L=136] Description: FUN_001807 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (136 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 459 (0.0179683); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1349.45 // Query: FUN_001808-T1 [L=287] Description: FUN_001808 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-56 190.3 0.0 7.3e-56 190.1 0.0 1.1 1 Carb_anhydrase Eukaryotic-type carbonic anhydrase Domain annotation for each model (and alignments): >> Carb_anhydrase Eukaryotic-type carbonic anhydrase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 190.1 0.0 2.8e-60 7.3e-56 2 253 .. 30 283 .. 29 285 .. 0.90 Alignments for each domain: == domain 1 score: 190.1 bits; conditional E-value: 2.8e-60 Carb_anhydrase 2 gpskWkekypscggkrQSPInietkkvkvdpslkplefegydkkkk..kltltNnGhtvqveleesekvtisggpleekeYraeqlhfHWgssss 94 gps+W++++p+c+g+rQSPIni t+++ +++ +pl ++ +d+ + + tl+N+ h ++e++e + ++++ggpl++ +Y+++q+hfH+g ++s FUN_001808-T1 30 GPSEWGRRWPQCDGRRQSPINIPTRRAINRR-HRPLIMT-FDTWRGlvTGTLKNTRHFPMLEIDEGRGAKLRGGPLRG-TYTLKQFHFHFGCANS 121 89*************************9888.6787776.6666655689*************99999********85.7*************** PP Carb_anhydrase 95 kGSEhtidgkrypaElhivhynskykslsealkkpdglavlavllevgdeeeneelekivealkkikkkgkstelk...efslsdLlp..eed.. 182 +GSEht++g+r++ Elh+v+ ++ + + d++av+a+ +++ +++ n+ l ++ + +ki ++++ +++ + ++ L+p + + FUN_001808-T1 122 RGSEHTLNGRRFSGELHLVFKKT--------TARGDEFAVVALWVQAPSRTGNRVLGRFADLTRKIIQPDSDETVRfsdGIFIRGLIPqrC-Ntr 207 ********************998........467799*********999989**************9999665555448999******752.246 PP Carb_anhydrase 183 ......ltkYyrYeGSLTtPpcsesVtWivfkepieiseeqlekfrkllsseeeeekeplvnnfRpvqplngRkVra 253 l+ Yy+Y+GSLTtP cse VtW+++k ++ +++ ++kfr+l + +++ + + +nfRpvqplngR+V++ FUN_001808-T1 208 fsrlaiLNCYYTYKGSLTTPICSEDVTWLIVKPWLPATNNMMRKFRRLETPAGKN-PPLMCDNFRPVQPLNGRTVFE 283 777877889***************************************9999985.779****************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (287 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 290 (0.0113525); expected 510.9 (0.02) Passed bias filter: 278 (0.0108828); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2962.32 // Query: FUN_001809-T1 [L=310] Description: FUN_001809 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-52 178.5 0.0 1.5e-51 175.9 0.0 1.9 1 Carb_anhydrase Eukaryotic-type carbonic anhydrase Domain annotation for each model (and alignments): >> Carb_anhydrase Eukaryotic-type carbonic anhydrase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 175.9 0.0 6.1e-56 1.5e-51 2 253 .. 36 306 .. 35 308 .. 0.83 Alignments for each domain: == domain 1 score: 175.9 bits; conditional E-value: 6.1e-56 Carb_anhydrase 2 gpskWkekypscggkrQSPInietkkvkvdpslkplefegydkkkk..kltltNnGhtvqveleesekvtisggpleekeYraeqlhfHWgssss 94 gps+W++++p+c+g+rQSPIni+t+++ +++ ++pl ++ +d+ + + tl+N+ h ++e++e + ++++ggpl++ +Y+++q+hfH+g ++s FUN_001809-T1 36 GPSEWGRRWPQCDGRRQSPINIRTRRAIYRR-YRPLIIT-FDTWRGlvTGTLKNTRHYPMLEIDEGRGAKVRGGPLRG-TYTLKQFHFHFGCANS 127 89****************************9.8999887.7776666799*************99999********85.7*************** PP Carb_anhydrase 95 kGSEhtidgkrypaElhivhynskykslsealkkpdglavlavlle...............vgdeee..neelekivealkkikkkgkstelk.. 170 +GSEht +g+r++ Elh+v+ +++ + d++av+a+ ++ ++ ++ n+ l ++ + +ki ++++ +++ FUN_001809-T1 128 RGSEHTRNGRRFSGELHLVFKKTT--------ARGDEFAVVALWVQltcsfhlcysnyrfnINAPSRigNRVLGRFADLTRKIIQPDSDETVRfs 214 ********************9994........3345555555555544444444444444443333334666999999999**999965555444 PP Carb_anhydrase 171 .efslsdLlp..eed........ltkYyrYeGSLTtPpcsesVtWivfkepieiseeqlekfrkllsseeeeekeplvnnfRpvqplngRkVra 253 + ++ L+p + + l+ Yy+Y+GSLTtP cse VtW+++k ++ +++ ++kfr+l + +++ + + +nfRp+qplngR+V++ FUN_001809-T1 215 dGIFIRGLIPqrC-NtrfsrlaiLNCYYTYKGSLTTPICSEDVTWLIVKPWLPATNNMMRKFRRLETPAGKN-PPLMCDNFRPIQPLNGRTVFE 306 8999******752.246777877889***************************************9999985.779****************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (310 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 377 (0.0147583); expected 510.9 (0.02) Passed bias filter: 352 (0.0137796); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.42s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3086.87 // Query: FUN_001810-T1 [L=201] Description: FUN_001810 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 735 (0.0287728); expected 510.9 (0.02) Passed bias filter: 617 (0.0241535); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 2056.49 // Query: FUN_001811-T1 [L=407] Description: FUN_001811 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.051 13.5 0.0 0.099 12.5 0.0 1.4 1 Bact_GSDM Bacterial Gasdermin Family Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 3.9e-06 0.099 129 162 .. 152 185 .. 139 208 .. 0.77 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 3.9e-06 Bact_GSDM 129 lkkgelyvitsvlksksfsvtaedengisveldv 162 +++el++itsv++s++f+v e+ + ++e v FUN_001811-T1 152 YQDHELLLITSVVYSEKFEVVGERGRMRQLESAV 185 5799****************99998877777666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (407 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1120 (0.0438442); expected 510.9 (0.02) Passed bias filter: 729 (0.0285379); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4023.16 // Query: FUN_001812-T1 [L=408] Description: FUN_001812 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.004 16.6 0.4 0.026 13.8 0.3 1.9 2 Mgr1 Mgr1-like, i-AAA protease complex subunit 0.0041 17.8 1.7 0.012 16.3 0.3 2.2 2 GST_C_3 Glutathione S-transferase, C-terminal domain ------ inclusion threshold ------ 0.065 13.7 0.5 0.13 12.7 0.5 1.4 1 DUF3801 Protein of unknown function (DUF3801) 0.14 12.9 0.1 0.35 11.6 0.1 1.6 1 GST_C Glutathione S-transferase, C-terminal domain Domain annotation for each model (and alignments): >> Mgr1 Mgr1-like, i-AAA protease complex subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.053 3.4e+02 93 116 .. 16 39 .. 4 65 .. 0.80 2 ! 13.8 0.3 4.1e-06 0.026 249 315 .. 247 323 .. 242 363 .. 0.80 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.053 Mgr1 93 diadlPsLnrfsttegelvvtaes 116 d +P Lnr s+t++ l++ ++ FUN_001812-T1 16 DANYVPILNRHSETTKPLSLIIKR 39 55679**********999874443 PP == domain 2 score: 13.8 bits; conditional E-value: 4.1e-06 Mgr1 249 eykPlsfseyLdrleyhLdmlellqekrkakeaskellekikeseeeleelieknkenrkkilkkl..........e 315 ++kP+s + ++++l y+ d ++ +e+ ++++ +l ++ ++ +++++++ +n ++i k++ + FUN_001812-T1 247 KCKPMSHTSFVEKLKYEHDPFNDDDEEDDDHAYDGQLSADVVADNTLPDDFTDQDMKNIERIFKNVlmtaksreqqK 323 58**************************9**************99999***************99966654322211 PP >> GST_C_3 Glutathione S-transferase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.22 1.4e+03 6 43 .. 224 261 .. 221 288 .. 0.77 2 ! 16.3 0.3 1.9e-06 0.012 24 86 .. 319 379 .. 299 381 .. 0.79 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.22 GST_C_3 6 piakllyeedekkkaekkkkfkeerlpkflkyfekvlk 43 ++ ++ly+++ kk + +k +f+ + p + f + lk FUN_001812-T1 224 KYCRVLYNKETKKLEIMKGEFVGKCKPMSHTSFVEKLK 261 67889998888888877777999998888777777664 PP == domain 2 score: 16.3 bits; conditional E-value: 1.9e-06 GST_C_3 24 kkfkeerlpkflkyfekvlkkngggylvgdklTyADlalfqvldgleepkakdllekypklka 86 ++ ++ ++k+l++fe++l+ + + l+ + lT D +++q+l+ ++ l ++ k+k+ FUN_001812-T1 319 REQQKALVKKYLRWFEEYLTADKMKILLDEPLTSNDCTFLQSLNVAAM--PDQQLLDFTKVKK 379 33578899***********************************95444..4555555777765 PP >> DUF3801 Protein of unknown function (DUF3801) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.5 2.1e-05 0.13 80 124 .. 297 341 .. 296 344 .. 0.91 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.1e-05 DUF3801 80 fkakDadaierafkeysakvlkkeekkpsvlkklekfkekvkqtk 124 f +D++ ier+fk++ + + +e++k v+k l+ f+e ++++k FUN_001812-T1 297 FTDQDMKNIERIFKNVLMTAKSREQQKALVKKYLRWFEEYLTADK 341 6779**********************************9998875 PP >> GST_C Glutathione S-transferase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.1 5.4e-05 0.35 22 83 .. 317 378 .. 304 379 .. 0.90 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 5.4e-05 GST_C 22 kevdealeevakvlsaleeelk..gktylvGdkltlADialvealdwleelklallrekfPnlk 83 k+ ++++ v+k+l +ee+l + + l ++ lt D+ ++ l+++++ + ll +f ++k FUN_001812-T1 317 KSREQQKALVKKYLRWFEEYLTadKMKILLDEPLTSNDCTFLQSLNVAAMPDQQLL--DFTKVK 378 5678889999*************999************************999998..777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (408 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1244 (0.0486984); expected 510.9 (0.02) Passed bias filter: 815 (0.0319045); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.44s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3910.09 // Query: FUN_001813-T1 [L=115] Description: FUN_001813 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.045 14.3 0.0 0.067 13.7 0.0 1.3 1 EF-hand_SWAP70_N Switch-associated protein 70-like, N-termin Domain annotation for each model (and alignments): >> EF-hand_SWAP70_N Switch-associated protein 70-like, N-terminal EF-hand domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 2.6e-06 0.067 9 37 .. 13 41 .. 8 60 .. 0.86 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2.6e-06 EF-hand_SWAP70_N 9 lksiwhaFtaLdveqsgkvsKsqLkVLsh 37 +k i a taLd+e++ vs+sqL+ L + FUN_001813-T1 13 EKEILAACTALDREKTSSVSRSQLQHLMT 41 79999*******************97765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 423 (0.016559); expected 510.9 (0.02) Passed bias filter: 403 (0.0157761); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.23u 0.38s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 1194.35 // Query: FUN_001814-T1 [L=587] Description: FUN_001814 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.16 12.3 3.3 13 6.1 0.0 2.7 2 Rv3651-like_C Rv3651-like, C-terminal domain 0.28 11.7 1.2 8.5 7.0 0.3 2.9 3 Type_III_YscG Bacterial type III secretion system chaperone Domain annotation for each model (and alignments): >> Rv3651-like_C Rv3651-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.001 13 22 80 .. 467 525 .. 460 533 .. 0.68 2 ? 5.1 1.4 0.0021 26 27 56 .. 534 562 .. 521 571 .. 0.82 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.001 Rv3651-like_C 22 dlkswkllkwldepcPfldwraeekeesvvhPddeaelasmaaefatGatsrvlrlras 80 d sw++ k ld+ +l+wr ++ +++ + a ma tG+ ++ l+ + FUN_001814-T1 467 DDSSWNFAKLLDHCNEYLNWRRSSDVSPRTESLIIAMEICMAGSNKTGPETKFCALKDT 525 7789*****************98754444444333333445555566666666666555 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0021 Rv3651-like_C 27 kllkwldepcPfldwraeekeesvvhPdde 56 ++ kw ++ P+++wr ++ + + +P+d+ FUN_001814-T1 534 RITKWWNNCWPYVEWRKSNVSV-QTDPQDN 562 678*************999654.5578775 PP >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.41 5.3e+03 19 36 .. 158 175 .. 157 186 .. 0.67 2 ? 7.0 0.3 0.00067 8.5 11 40 .. 186 215 .. 176 230 .. 0.70 3 ? 5.6 0.1 0.0018 24 14 38 .. 207 231 .. 204 254 .. 0.78 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.41 Type_III_YscG 19 qhcheeaniiaewlerkg 36 +h +ea +i++ l + g FUN_001814-T1 158 NHTGNEADCISQDLITSG 175 577788888877665544 PP == domain 2 score: 7.0 bits; conditional E-value: 0.00067 Type_III_YscG 11 eialvGsGqhcheeaniiaewlerkgeeea 40 + l+ G h +ean+i+ l +g+ FUN_001814-T1 186 SLDLIADGTHTGNEANCISSDLIGNGNSAG 215 677899999999999999888777666533 PP == domain 3 score: 5.6 bits; conditional E-value: 0.0018 Type_III_YscG 14 lvGsGqhcheeaniiaewlerkgee 38 l+G G+ +ean+i+ l +g++ FUN_001814-T1 207 LIGNGNSAGNEANCISSDLIANGNH 231 89*************9988777654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (587 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 504 (0.0197299); expected 510.9 (0.02) Passed bias filter: 421 (0.0164807); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 5688.32 // Query: FUN_001815-T1 [L=254] Description: FUN_001815 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.6 12.4 35 4.7 0.1 5.3 5 Duc1_FFAT_like Duc1 FFAT-like motif Domain annotation for each model (and alignments): >> Duc1_FFAT_like Duc1 FFAT-like motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.3 0.013 3.3e+02 7 14 .. 43 49 .. 41 50 .. 0.87 2 ? 4.7 0.1 0.0014 35 2 14 .. 80 91 .. 79 92 .. 0.90 3 ? 4.7 0.1 0.0014 35 2 14 .. 122 133 .. 121 134 .. 0.90 4 ? 4.7 0.1 0.0014 35 2 14 .. 164 175 .. 163 176 .. 0.90 5 ? 1.1 0.1 0.019 4.8e+02 9 14 .. 212 217 .. 207 217 .. 0.86 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.013 Duc1_FFAT_like 7 eNEedLQR 14 e Ee LQR FUN_001815-T1 43 E-EEELQR 49 4.9****9 PP == domain 2 score: 4.7 bits; conditional E-value: 0.0014 Duc1_FFAT_like 2 ntsdDeNEedLQR 14 n+s e Ee LQR FUN_001815-T1 80 NSSNKE-EEELQR 91 889999.*****9 PP == domain 3 score: 4.7 bits; conditional E-value: 0.0014 Duc1_FFAT_like 2 ntsdDeNEedLQR 14 n+s e Ee LQR FUN_001815-T1 122 NSSNKE-EEELQR 133 889999.*****9 PP == domain 4 score: 4.7 bits; conditional E-value: 0.0014 Duc1_FFAT_like 2 ntsdDeNEedLQR 14 n+s e Ee LQR FUN_001815-T1 164 NSSNKE-EEELQR 175 889999.*****9 PP == domain 5 score: 1.1 bits; conditional E-value: 0.019 Duc1_FFAT_like 9 EedLQR 14 Ee LQR FUN_001815-T1 212 EEELQR 217 8****9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (254 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2665 (0.104326); expected 510.9 (0.02) Passed bias filter: 529 (0.0207086); expected 510.9 (0.02) Passed Vit filter: 184 (0.00720298); expected 25.5 (0.001) Passed Fwd filter: 87 (0.00340575); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.64u 0.43s 00:00:01.07 Elapsed: 00:00:00.44 # Mc/sec: 2305.48 // Query: FUN_001816-T1 [L=191] Description: FUN_001816 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-26 93.0 3.1 2.6e-26 93.0 3.1 1.7 2 Serinc Serine incorporator (Serinc) ------ inclusion threshold ------ 0.11 13.0 0.0 0.18 12.4 0.0 1.3 1 CCD WisP family C-Terminal Region Domain annotation for each model (and alignments): >> Serinc Serine incorporator (Serinc) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 93.0 3.1 2e-30 2.6e-26 349 430 .. 20 101 .. 2 104 .. 0.86 2 ? -2.6 1.8 0.21 2.7e+03 313 361 .. 129 176 .. 109 180 .. 0.40 Alignments for each domain: == domain 1 score: 93.0 bits; conditional E-value: 2e-30 Serinc 349 eeekkkakddekegvkYsYsfFHlifflaslYvamlLTnwvspeeakdfakvgrswaavWvkivssWvclllYlWtLvAPlv 430 ++++++ +++ e+v+Y+Ys+F +i+fla+lY++m+LTnw+sp++a+d +++ rsw+avW+k+ ss +cl+lY+W L+ P++ FUN_001816-T1 20 KSSDAECMEKTVEEVTYNYSLFTFIIFLATLYIMMTLTNWYSPTQATDISRLARSWPAVWIKMGSSSACLCLYIWKLLVPVF 101 33346778888899******************************************************************96 PP == domain 2 score: -2.6 bits; conditional E-value: 0.21 Serinc 313 lklkksveeqeeekeelraealkeaveegslpesaleeekkkakddeke 361 +k++ ++ + + ++ ++ +alk++ + +l+++ +e+ +k+++++e++ FUN_001816-T1 129 SKETPNNVHDVKPERAVSNQALKKKRHG-NLETQYDETLTKRHIEKERQ 176 2222222233333333333333333332.33333322225555555555 PP >> CCD WisP family C-Terminal Region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.4e-05 0.18 24 97 .. 77 151 .. 67 167 .. 0.79 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.4e-05 CCD 24 gfwskvgsgiaapfkwiwhgitwpfrklfgsrseapssttnatgntsgktrvkrdtpttp.pehplksvndqitk 97 +w k+gs a+ +iw+ + fr +f +e+ + + + + ++tp +p ++v +q k FUN_001816-T1 77 AVWIKMGSSSACLCLYIWKLLVPVFRSMFDGDTESAAIQSHGVRGQANYEQSSKETPNNVhDVKPERAVSNQALK 151 57***************************9999887776666555555666666777654144677777777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (191 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1415 (0.0553924); expected 510.9 (0.02) Passed bias filter: 688 (0.0269329); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.24u 0.42s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1986.02 // Query: FUN_001817-T1 [L=410] Description: FUN_001817 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.009 15.9 0.0 0.015 15.2 0.0 1.2 1 SAM_MT Putative SAM-dependent methyltransferase ------ inclusion threshold ------ 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 Bact_GSDM Bacterial Gasdermin Family 0.23 12.2 0.0 1 10.1 0.0 2.0 2 Kindlin_2_N Kindlin-2 N-terminal domain Domain annotation for each model (and alignments): >> SAM_MT Putative SAM-dependent methyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 1.7e-06 0.015 142 186 .. 299 346 .. 290 353 .. 0.81 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.7e-06 SAM_MT 142 ekleekpdvvylDPmyPh...kkksalvKKemrvfqqlvGadedadeL 186 ++ +++ + +y+ + P ++++alvKK +r f++l+G+de L FUN_001817-T1 299 DQDKKNIERIYINVLMPAksrEQQKALVKKYLRWFENLLGNDETKILL 346 4556678889999999984446789****************9876555 PP >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 3.6e-05 0.31 105 162 .. 133 185 .. 123 196 .. 0.76 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 3.6e-05 Bact_GSDM 105 leLgnyLkaadidvdnpslgllkklkkgelyvitsvlksksfsvtaedengisveldv 162 +eL +L +a++ d +++ + k +el++its + s++f+v e++ + +ve + FUN_001817-T1 133 VELRGILHSAAL--DGEKMMPY---KGQELFLITSLVCSEKFEVMGERKHKREVEARL 185 666666666666..44444444...559*********************999998765 PP >> Kindlin_2_N Kindlin-2 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.48 4e+03 40 64 .. 79 103 .. 74 114 .. 0.77 2 ? 10.1 0.0 0.00012 1 7 45 .. 360 398 .. 354 407 .. 0.85 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.48 Kindlin_2_N 40 lveklditkdwsdyalwwekkkkwl 64 +v++ + kd sd a w e+ + + FUN_001817-T1 79 VVQEQVMEKDKSDPARWCEEIACNI 103 5666678899999999999877655 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00012 Kindlin_2_N 7 elkitvtdleikkevkiklrvkgdlhiGGvllklvekld 45 +++v+ + ++k++++ +++h G++lkl+++l FUN_001817-T1 360 LRSLYVSAIPGQKSLDFTSVKEAEIHRCGLILKLLDELS 398 5578999999*********9****************995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (410 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 875 (0.0342533); expected 510.9 (0.02) Passed bias filter: 772 (0.0302212); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4006.31 // Query: FUN_001818-T1 [L=167] Description: FUN_001818 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.037 14.5 0.1 16 6.1 0.0 2.4 2 EAD10 Effector-associated domain 10 Domain annotation for each model (and alignments): >> EAD10 Effector-associated domain 10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.00068 17 3 17 .. 115 129 .. 114 132 .. 0.85 2 ? 6.1 0.0 0.00063 16 5 19 .. 143 157 .. 140 167 .] 0.81 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.00068 EAD10 3 nseelkailerilng 17 + ++l++i++ril+ FUN_001818-T1 115 SYNDLNKIFKRILQD 129 579*********986 PP == domain 2 score: 6.1 bits; conditional E-value: 0.00063 EAD10 5 eelkailerilngqq 19 ++l++ileril++ q FUN_001818-T1 143 KDLNKILERILQEPQ 157 79*********8654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 946 (0.0370327); expected 510.9 (0.02) Passed bias filter: 739 (0.0289293); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1639.20 // Query: FUN_001819-T1 [L=237] Description: FUN_001819 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (237 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 751 (0.0293991); expected 510.9 (0.02) Passed bias filter: 566 (0.022157); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2342.59 // Query: FUN_001820-T1 [L=109] Description: FUN_001820 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (109 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 327 (0.0128009); expected 510.9 (0.02) Passed bias filter: 297 (0.0116265); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.35s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1099.62 // Query: FUN_001821-T1 [L=92] Description: FUN_001821 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (92 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 266 (0.010413); expected 510.9 (0.02) Passed bias filter: 202 (0.00790761); expected 510.9 (0.02) Passed Vit filter: 8 (0.000313173); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.35s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 972.99 // Query: FUN_001822-T1 [L=403] Description: FUN_001822 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.2 11.5 0.0 0.52 10.2 0.0 1.7 2 Bact_GSDM Bacterial Gasdermin Family Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 0.27 6.9e+03 9 20 .. 31 42 .. 28 83 .. 0.63 2 ? 10.2 0.0 2e-05 0.52 130 157 .. 153 180 .. 134 197 .. 0.88 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 0.27 Bact_GSDM 9 kPLqlllrkgsk 20 kPL+l++++++ FUN_001822-T1 31 KPLSLIIKRKRP 42 788888877764 PP == domain 2 score: 10.2 bits; conditional E-value: 2e-05 Bact_GSDM 130 kkgelyvitsvlksksfsvtaedengis 157 +++el++itsv++s++f+ +++++++ FUN_001822-T1 153 QDQELFLITSVVYSEKFELVGKRKQEQG 180 789***************9999988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (403 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1157 (0.0452926); expected 510.9 (0.02) Passed bias filter: 822 (0.0321785); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4059.54 // Query: FUN_001822-T2 [L=302] Description: FUN_001822 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.18 11.6 0.0 0.34 10.8 0.0 1.4 1 Bact_GSDM Bacterial Gasdermin Family Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 1.3e-05 0.34 130 157 .. 57 84 .. 38 104 .. 0.88 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 1.3e-05 Bact_GSDM 130 kkgelyvitsvlksksfsvtaedengis 157 +++el++itsv++s++f+ +++++++ FUN_001822-T2 57 QDQELFLITSVVYSEKFELVGKRKQEQG 84 789***************9999998876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (302 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1124 (0.0440008); expected 510.9 (0.02) Passed bias filter: 815 (0.0319045); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2953.88 // Query: FUN_001823-T1 [L=202] Description: FUN_001823 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0018 18.5 8.9 0.0024 18.1 8.9 1.1 1 GET2 GET complex subunit GET2 ------ inclusion threshold ------ 0.15 12.3 7.6 0.25 11.5 7.6 1.3 1 SMYLE_N Short myomegalin-like EB1 binding proteins, N-termi Domain annotation for each model (and alignments): >> GET2 GET complex subunit GET2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 8.9 1.9e-07 0.0024 56 175 .. 32 161 .. 4 165 .. 0.48 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 1.9e-07 GET2 56 passtasssasas...ehddpeiediseiavkpkktaskkkkspsseesepeap............eldqllkqllqqqqqgngenkqdaesstPd 136 +++s+a + + ++p++e + +++ ++sk+ k +s ++ +p+++ +++q+ + ++ + + e+++++ ++ d FUN_001823-T1 32 ETESSAVN----EvesGAAEPNTESSAAQVNTT--QTSKPPKRKSGKDGKPKKKprlcdvveqsneQMRQMQDYMQSN-SVTL-EERSKEREGDRD 119 22222222....122223333333322221111..1112222222222222222244444443334899765555544.3333.33344556677* PP GET2 137 lfsqllksmkqgegk...kakseeetssspeeaevqqqlley 175 +f q+l +m+q++ + + + +++ +p+ +++ q +++ FUN_001823-T1 120 FFRQMLGMMSQTMMGmtqMLVQGAGSGYHPSTQAYSPQSVQP 161 ***********9999677445555555555555555555554 PP >> SMYLE_N Short myomegalin-like EB1 binding proteins, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 7.6 2e-05 0.25 87 171 .. 6 96 .. 3 111 .. 0.61 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 2e-05 SMYLE_N 87 tRysasvveee.......ssvselvaaeleeekspaegesleegspasSvesLdttvevsppqqkeeeedkeekesaksdqlseekttaess 171 tR+s+ ve+ ss++ +++ ++ +++ ++ +e+ sS++ ++tt +++pp++k + k++k+ +d +++ + ++ ++ FUN_001823-T1 6 TRWSTHPVEDPpdehlmeSSAKGESYETE-SSAVNEVESGAAEPNTESSAAQVNTTQTSKPPKRKSGKDGKPKKKPRLCDVVEQSNEQMRQM 96 89999886555222222122222222222.222222222334888999*******************9999999999999776654444332 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (202 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1871 (0.0732433); expected 510.9 (0.02) Passed bias filter: 934 (0.0365629); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.36s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2023.14 // Query: FUN_001825-T1 [L=252] Description: FUN_001825 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-05 24.8 0.0 3.8e-05 24.2 0.0 1.3 1 RT_RNaseH_2 RNase H-like domain found in reverse transcri ------ inclusion threshold ------ 0.26 12.5 0.0 0.45 11.7 0.0 1.4 1 Asp_protease_2 Aspartyl protease Domain annotation for each model (and alignments): >> RT_RNaseH_2 RNase H-like domain found in reverse transcriptase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 3e-09 3.8e-05 1 53 [. 198 250 .. 198 252 .] 0.95 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 3e-09 RT_RNaseH_2 1 WteeqekafeklkealtsapvLahpdpdkpfiletDaSdvgiGavLsqedddg 53 W +e+++af++lk++++s++v a+ dp+++++ +++ S +g++a L+ +++++ FUN_001825-T1 198 WRKENTEAFDELKNMISSDKVKAYCDPEATLERHVNRSPMGLAATLTRKRPGE 250 99*********************************************999854 PP >> Asp_protease_2 Aspartyl protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 3.6e-05 0.45 3 36 .. 147 180 .. 145 196 .. 0.91 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3.6e-05 Asp_protease_2 3 vtinGkpvrflvDTGAsstviseslaerlglkle 36 v i G +++l D+GA+++ ++e++ +r gl+ + FUN_001825-T1 147 VIICGAVITVLPDSGATISDMDEATFQRYGLERK 180 779999************************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (252 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1070 (0.0418869); expected 510.9 (0.02) Passed bias filter: 794 (0.0310824); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 2462.30 // Query: FUN_001826-T1 [L=375] Description: FUN_001826 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-31 109.8 0.3 3e-31 109.2 0.3 1.3 1 Aspzincin_M35 Lysine-specific metallo-endopeptidase 1.7e-09 37.6 0.3 0.00047 19.7 0.2 2.1 2 Peptidase_M35 Deuterolysin metalloprotease (M35) family Domain annotation for each model (and alignments): >> Aspzincin_M35 Lysine-specific metallo-endopeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.2 0.3 2.3e-35 3e-31 5 141 .. 244 368 .. 240 369 .. 0.90 Alignments for each domain: == domain 1 score: 109.2 bits; conditional E-value: 2.3e-35 Aspzincin_M35 5 assstkryttwFgttsasrkstVashfskikkeessnsgsltydcsdgkckesevlAYtlpssnvivlcpafwslpeltskctgtdskagtivHEl 100 ++++ ++twFg ++ +++ + f++++++ +s+++ty+++ +c+ s+v+AYt+++s+ i+lc+++ + ++ +g d+k g++ HEl FUN_001826-T1 244 PQTKNPLVETWFG---INQVNNAVTKFQEMADV--LSSETMTYTFDGPHCR-SNVFAYTYKQSREIFLCQLYKVA----KTIEGSDNKMGILTHEL 329 56788899*****...55567777788888888..9**********9***9.******************99764....5999************* PP Aspzincin_M35 101 tHftavagtdDiaYgqsaakslaksspsqAinNADsyelFa 141 +H+ tdDi+Ygqs++++lak+ p++AinNAD++e+F FUN_001826-T1 330 SHAI--ISTDDIVYGQSGCRELAKNAPNKAINNADNFEYFL 368 **99..**********************************7 PP >> Peptidase_M35 Deuterolysin metalloprotease (M35) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 4e-07 0.0051 69 140 .. 74 143 .. 43 191 .. 0.85 2 ! 19.7 0.2 3.7e-08 0.00047 239 346 .. 269 369 .. 213 373 .. 0.81 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 4e-07 Peptidase_M35 69 kkvslyreetevefeGikrrlrteGlteealttlaaGetledefdiastsdlseGGavtirsdGfvpivtdg 140 +++ r+++++ef+Gi r+ + G + + t+++Getl f+++ + d+++ G ++ d ++ v+++ FUN_001826-T1 74 DCLTVTRNGKKLEFDGIYRKRSVPG--PDQFLTVKPGETLSSMFQVSDAFDMTKAGEYSVAVDTYLEYVVGS 143 456899************9988888..5778889**************************999998877765 PP == domain 2 score: 19.7 bits; conditional E-value: 3.7e-08 Peptidase_M35 239 keasstssGsttyycndtyGycesnvlaytlpakniiancdiyysylpalastchaqdqatttl.hefthapgvyspGtddlgyGydaatalsa.. 331 + a+ ss + ty + + +c snv ayt + +i c++y +a+t d+ l he++ha tdd+ yG + + +l+ FUN_001826-T1 269 EMADVLSSETMTYTFDGP--HCRSNVFAYTYKQSREIFLCQLYK-----VAKTIEGSDNKMGILtHELSHAI----ISTDDIVYGQSGCRELAKna 353 345666777777766665..7*************9999999884.....67888877776655549****95....47**********99997522 PP Peptidase_M35 332 .sqallnadsyalyan 346 ++a++nad + + + FUN_001826-T1 354 pNKAINNADNFEYFLE 369 268******9988865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (375 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 628 (0.0245841); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3700.78 // Query: FUN_001827-T1 [L=102] Description: FUN_001827 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.043 13.6 0.1 0.05 13.4 0.1 1.1 1 HipA_2 HipA-like kinase Domain annotation for each model (and alignments): >> HipA_2 HipA-like kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.1 1.9e-06 0.05 172 230 .. 16 75 .. 2 79 .. 0.72 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 1.9e-06 HipA_2 172 reiledlvdraeyeeklekalesldeiiakiPeeWlesdeeqtvkaeldl.eeiektLer 230 + ++ ++ ye+kl++ ++ +d+++ ++P++ + +++++ +k + ++ + +L+r FUN_001827-T1 16 NIASFSFLRKQAYENKLSNNMNVFDSVVVSVPNNNYLRKKKKRKKQNKAKdKNTKFLLHR 75 444568899***********************9887777776655554440444445555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2671 (0.104561); expected 510.9 (0.02) Passed bias filter: 878 (0.0343707); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.43s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1030.98 // Query: FUN_001828-T1 [L=199] Description: FUN_001828 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (199 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 668 (0.0261499); expected 510.9 (0.02) Passed bias filter: 591 (0.0231356); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1970.87 // Query: FUN_001829-T1 [L=115] Description: FUN_001829 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 SBDS_domain_II SBDS protein, domain II Domain annotation for each model (and alignments): >> SBDS_domain_II SBDS protein, domain II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 7.3e-06 0.19 24 47 .. 75 98 .. 73 102 .. 0.92 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 7.3e-06 SBDS_domain_II 24 mIekalkelkfsvdpnksakeQal 47 +I +al+++ ++++++++++eQ + FUN_001829-T1 75 VIARALEKAVYKIHTQRPVEEQLQ 98 699*******************86 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 493 (0.0192993); expected 510.9 (0.02) Passed bias filter: 381 (0.0149149); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1178.65 // Query: FUN_001831-T1 [L=95] Description: FUN_001831 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (95 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 629 (0.0246232); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 967.64 // Query: FUN_001834-T1 [L=371] Description: FUN_001834 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-25 89.6 0.1 5.5e-25 88.9 0.1 1.3 1 Aspzincin_M35 Lysine-specific metallo-endopeptidase 0.00016 21.2 0.2 0.0053 16.2 0.0 2.2 2 Peptidase_M35 Deuterolysin metalloprotease (M35) family Domain annotation for each model (and alignments): >> Aspzincin_M35 Lysine-specific metallo-endopeptidase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 88.9 0.1 4.3e-29 5.5e-25 6 141 .. 245 368 .. 240 369 .. 0.88 Alignments for each domain: == domain 1 score: 88.9 bits; conditional E-value: 4.3e-29 Aspzincin_M35 6 ssstkryttwFgttsasrkstVashfskikkees.snsgsltydcsdgkckesevlAYtlpssnvivlcpafwslpeltskctgtdskagtivHEl 100 + +++ ++twFg +++V + +k+++ + ++ ++ty+++ +c+ +++AYt ++s+ i+lc+++ ++ +g +sk g++ HEl FUN_001834-T1 245 QAKKDLVKTWFG------ENQVDNAVTKFQSMVDlLKTAKITYTFDGPQCD-RKTFAYTFKQSREIFLCQLYKDAD----ILQGPNSKMGILTHEL 329 667889******......4455555555555555599999***99999**9.**********************65....68999*********** PP Aspzincin_M35 101 tHftavagtdDiaYgqsaakslaksspsqAinNADsyelFa 141 +H+ tdDi+Ygq +k lak p+ Ai+NAD++e+F FUN_001834-T1 330 SHAI--ISTDDIVYGQFVCKMLAKFVPNYAISNADNFEYFL 368 **99..**********************************7 PP >> Peptidase_M35 Deuterolysin metalloprotease (M35) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 4.1e-07 0.0053 68 140 .. 73 143 .. 42 153 .. 0.80 2 ! 2.9 0.1 0.0048 61 259 345 .. 287 368 .. 262 371 .] 0.71 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 4.1e-07 Peptidase_M35 68 vkkvslyreetevefeGikrrlrteGlteealttlaaGetledefdiastsdlseGGavtirsdGfvpivtdg 140 +++ r+++++ef+Gi r+ + G + + t++aGetl f+++ + d+++ G ++ d ++ v+++ FUN_001834-T1 73 TDCLTVTRNGKKLEFDGIYRKRSVPG--PDQFLTVKAGETLSSMFQVSDAFDMTKAGEYSVAVDTYLEYVVGS 143 4557899************9988888..57788899*************************999998777665 PP == domain 2 score: 2.9 bits; conditional E-value: 0.0048 Peptidase_M35 259 ycesnvlaytlpakniiancdiyysylpalastchaqdqatttlhefthapgvyspGtddlgyGydaatalsa...sqallnadsyalya 345 c+ + ayt+ + +i c++y l + + he++ha tdd+ yG + l+ + a+ nad + + FUN_001834-T1 287 QCDRKTFAYTFKQSREIFLCQLYKD-ADILQGP---NSKMGILTHELSHAI----ISTDDIVYGQFVCKMLAKfvpNYAISNADNFEYFL 368 5999999999999999999998754.3344332...233445559999985....46999999987777665322278999999988775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (371 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 610 (0.0238794); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3585.98 // Query: FUN_001835-T1 [L=200] Description: FUN_001835 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (200 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 605 (0.0236837); expected 510.9 (0.02) Passed bias filter: 569 (0.0222744); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2005.14 // Query: FUN_001836-T1 [L=76] Description: FUN_001836 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (76 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 520 (0.0203562); expected 510.9 (0.02) Passed bias filter: 445 (0.0174202); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 767.81 // Query: FUN_001837-T1 [L=254] Description: FUN_001837 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0081 16.6 1.2 0.015 15.8 1.2 1.3 1 Lysostaphin_N Lysostaphin, N-terminal domain Domain annotation for each model (and alignments): >> Lysostaphin_N Lysostaphin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 1.2 5.7e-07 0.015 5 92 .. 57 144 .. 53 149 .. 0.74 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 5.7e-07 Lysostaphin_N 5 amShvgVeyksviamShvgveyksviamSkvgVeyksviamShvgVeyksviamskvgVeyksviapshvgVeyksviemSkvgVeyk 92 ++S+++V ++ +++ +v + +++ +V + ++ +S+++V + +++ +V + + ++ + V + +++ +S++ V++ FUN_001837-T1 57 NTSDLPVRQREKVKAEYLPVRQRKRVTSHVLPVGQVQKVTTSDLPVRQREKVKGEFLPVRQRKTVKAHDLHVGQGQKMRTSDLSVRQR 144 5677788888888888888888888877777888888888888888888888888888888888888888888888888887777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (254 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 731 (0.0286162); expected 510.9 (0.02) Passed bias filter: 591 (0.0231356); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2472.62 // Query: FUN_001838-T1 [L=157] Description: FUN_001838 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-19 69.2 0.2 5.3e-19 68.6 0.2 1.2 1 CD225 Interferon-induced transmembrane protein 0.0057 17.5 1.0 0.0074 17.1 1.0 1.3 1 DUF4620 Domain of unknown function (DUF4620) 0.0068 16.9 0.1 0.012 16.2 0.1 1.3 1 VMA21 VMA21-like domain ------ inclusion threshold ------ 0.05 13.6 0.2 0.065 13.2 0.2 1.0 1 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> CD225 Interferon-induced transmembrane protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.6 0.2 8.3e-23 5.3e-19 2 67 .. 80 145 .. 79 146 .. 0.97 Alignments for each domain: == domain 1 score: 68.6 bits; conditional E-value: 8.3e-23 CD225 2 PkdylvwsifstlfcclplGivAlvySvkvrdrkaaGdlegAqrasskAkllniislvlglviiil 67 P+d+ ++++fs+l+c++p+Gi+A+ +S++v + a+Gd+++A+ as+ k+++ +++v+g++++++ FUN_001838-T1 80 PEDHKTLAWFSCLCCFWPVGIMAVLKSTEVHNHLARGDVNAAKIASDDVKKYARLAVVIGIILLVV 145 89************************************************************9987 PP >> DUF4620 Domain of unknown function (DUF4620) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 1.0 1.2e-06 0.0074 22 78 .. 42 99 .. 18 124 .. 0.76 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.2e-06 DUF4620 22 tpgwpsrdqeapgsmmppaaaqpsa.hgalvppatahe...pvdhpalhwlacccclslpg 78 a g +p + a ps +g +v + +e p dh +l w++c cc+ g FUN_001838-T1 42 HSS---YPAHATGQAIPGCQALPSRqRGNMVMCQVIQEttiPEDHKTLAWFSCLCCFWPVG 99 444...4457899999999999996268899887776644488*************86555 PP >> VMA21 VMA21-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.1 1.8e-06 0.012 4 62 .. 84 150 .. 82 151 .. 0.95 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.8e-06 VMA21 4 kkLllfsilmvllPlaiffllknllfdg........yfglssedstlySgilAVivvnvvlalYiyr 62 k+L +fs l + P++i+ +lk++ ++ +++s d+ y+ ++ Vi++++ ++++++r FUN_001838-T1 84 KTLAWFSCLCCFWPVGIMAVLKSTEVHNhlargdvnAAKIASDDVKKYARLAVVIGIILLVVVFVFR 150 799*********************999999999999999999**********************997 PP >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.2 1e-05 0.065 133 215 .. 66 148 .. 53 152 .. 0.78 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1e-05 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 133 keetvClidfpeeestwevsytlllsvlgfllpllvilvcy.vrilrtlrksakkekskkkksarkerkalktllvvvvvfvlc 215 + +C++ ++++ + ++++++++++++f p+ +++v+ + + +l + ++++ ++++++k ++++ +++++++v v++ FUN_001838-T1 66 GNMVMCQVIQETTIPEDHKTLAWFSCLCCFW-PVGIMAVLKsTEVHNHLARGDVNAAKIASDDVKKYARLAVVIGIILLVVVFV 148 77889*9999997767999999999998887.8888888862677888888888888888888888889999888887776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1226 (0.0479937); expected 510.9 (0.02) Passed bias filter: 837 (0.0327657); expected 510.9 (0.02) Passed Vit filter: 86 (0.00336661); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1552.22 // Query: FUN_001840-T1 [L=406] Description: FUN_001840 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0037 17.2 0.0 0.0067 16.3 0.0 1.4 1 Bact_GSDM Bacterial Gasdermin Family Domain annotation for each model (and alignments): >> Bact_GSDM Bacterial Gasdermin Family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 2.6e-07 0.0067 99 162 .. 126 184 .. 121 197 .. 0.76 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 2.6e-07 Bact_GSDM 99 rdtvdlleLgnyLkaadidvdnpslgllkklkkgelyvitsvlksksfsvtaedengisveldv 162 ++++ l+L +L++ + d +++ + +++el++itsv++s++f+v e+ ++ +ve + FUN_001840-T1 126 EEYITDLDLRGILSRTVL--DADKMTPY---QDQELFLITSVVYSEKFEVVGERRQEREVEARL 184 556666666666665555..44444444...5599*******************9999998755 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (406 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 953 (0.0373067); expected 510.9 (0.02) Passed bias filter: 695 (0.0272069); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4083.46 // Query: FUN_001841-T1 [L=855] Description: FUN_001841 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-125 420.1 0.0 2e-125 419.7 0.0 1.1 1 MYCBPAP MYCBP-associated protein family Domain annotation for each model (and alignments): >> MYCBPAP MYCBP-associated protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 419.7 0.0 7.9e-130 2e-125 2 439 .] 208 633 .. 207 633 .. 0.92 Alignments for each domain: == domain 1 score: 419.7 bits; conditional E-value: 7.9e-130 MYCBPAP 2 sqdkrLknWkktlaeRkkqqerisrklgkpaeellmnrsetyRekqeerrlldrarpeletpkklrvgsefwsqleelgdeeeltglslTltkaer 97 ++ ++L nW+k++ +Rkkqq+++s l + + l+mn+se+yRe+qe r ++dra+p +e++k++rvgsefw+q e++gd+ tg+++Tlt++er FUN_001841-T1 208 NESNALSNWQKQMMQRKKQQQYLSDLLRTSTDMLVMNQSEEYRETQENRYIIDRAIPSTEYGKGYRVGSEFWKQAEQIGDD--ETGINVTLTQTER 301 5789*****************************************************************************..************* PP MYCBPAP 98 ggpeeveivglPeviqkElgl..kkeakeakkeskWdrSevLkeRrkelkedlkellefepDidgLeVvGkgkekkellgeeplstvseeseesls 191 g+p+ +e++g+P i+ E+g +++++ + ++ W +S +L+eR ++l+ l+el++++p id LeV+G+++ + + +++s v+ee+ FUN_001841-T1 302 GYPSAIEHIGKPIYIKNEMGIewSSTQRSTSVHYPWRKSTYLQERTRQLQPALRELDPHQPYIDDLEVIGTSQ-PRRSSKFDMMSVVQEEE----- 391 **********************9888899*******************************************9.22222222222222222..... PP MYCBPAP 192 leeeeeeseseseedse.eldplaekpdvvpepilgpslkingkearweeksss..kesv..elrltFecdpgqekvksvltleNnGttaiwysWr 282 e +es dpla+ dvvp+pi+gpsl i g++a+w++++ + ++v + r+ Fe++ g ++v+s+l + N+Gttai++sW+ FUN_001841-T1 392 ----EMDMLNES----GfGRDPLANIADVVPQPIFGPSLSISGHTAQWNGSREQrvPGQVgvASRVIFEANVG-DRVTSHLNICNDGTTAIYFSWK 478 ....22122222....235799*****************************99988666677***********.********************** PP MYCBPAP 283 rlekkkafgslkkeseeqrFyFdteegvllpGetrnikvlFksrkvgifkerWeLrthPsllggaslqvrLhGvctaedrekleerkqlekelaqr 378 ++++ ++ g++ ++qrFyFdt++gv+l G+t n+ ++Fks ++gif+e+WeL t+P l+gga + + L+Gv++++d + +e r+++e+ela+r FUN_001841-T1 479 NIPRANSLGTK-LAGRTQRFYFDTKSGVILSGDTLNFPFVFKSPNAGIFTETWELMTKPILCGGAPIRIHLRGVAVEDD-IYKEARQRIEEELARR 572 *********98.55667**************************************************************.**************** PP MYCBPAP 379 eaetkvrsllaellpgvetperpksPyerylteeelFnakNpplyyreddveaLkeLykqv 439 ea+++ +++l+e+l+gv+tper++sP+++y+teee+F + N +y++ + v++Lk++y q+ FUN_001841-T1 573 EAVETAARILNEILDGVRTPERARSPVDAYITEEEIFGRVNEGMYFQDEIVQELKQIYAQL 633 *****************************************99***************985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (855 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1631 (0.0638481); expected 510.9 (0.02) Passed bias filter: 911 (0.0356626); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.45u 0.39s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 8130.39 // Query: FUN_001841-T2 [L=855] Description: FUN_001841 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-125 420.1 0.0 2e-125 419.7 0.0 1.2 1 MYCBPAP MYCBP-associated protein family Domain annotation for each model (and alignments): >> MYCBPAP MYCBP-associated protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 419.7 0.0 7.9e-130 2e-125 2 439 .] 208 633 .. 207 633 .. 0.92 Alignments for each domain: == domain 1 score: 419.7 bits; conditional E-value: 7.9e-130 MYCBPAP 2 sqdkrLknWkktlaeRkkqqerisrklgkpaeellmnrsetyRekqeerrlldrarpeletpkklrvgsefwsqleelgdeeeltglslTltkaer 97 ++ ++L nW+k++ +Rkkqq+++s l + + l+mn+se+yRe+qe r ++dra+p +e++k++rvgsefw+q e++gd+ tg+++Tlt++er FUN_001841-T2 208 NESNALSNWQKQMMQRKKQQQYLSDLLRTSTDMLVMNQSEEYRETQENRYIIDRAIPSTEYGKGYRVGSEFWKQAEQIGDD--ETGINVTLTQTER 301 5789*****************************************************************************..************* PP MYCBPAP 98 ggpeeveivglPeviqkElgl..kkeakeakkeskWdrSevLkeRrkelkedlkellefepDidgLeVvGkgkekkellgeeplstvseeseesls 191 g+p+ +e++g+P i+ E+g +++++ + ++ W +S +L+eR ++l+ l+el++++p id LeV+G+++ + + +++s v+ee+ FUN_001841-T2 302 GYPSAIEHIGKPIYIKNEMGIewSSTQRSTSVHYPWRKSTYLQERTRQLQPALRELDPHQPYIDDLEVIGTSQ-PRRSSKFDMMSVVQEEE----- 391 **********************9888899*******************************************9.22222222222222222..... PP MYCBPAP 192 leeeeeeseseseedse.eldplaekpdvvpepilgpslkingkearweeksss..kesv..elrltFecdpgqekvksvltleNnGttaiwysWr 282 e +es dpla+ dvvp+pi+gpsl i g++a+w++++ + ++v + r+ Fe++ g ++v+s+l + N+Gttai++sW+ FUN_001841-T2 392 ----EMDMLNES----GfGRDPLANIADVVPQPIFGPSLSISGHTAQWNGSREQrvPGQVgvASRVIFEANVG-DRVTSHLNICNDGTTAIYFSWK 478 ....22122222....235799*****************************99988666677***********.********************** PP MYCBPAP 283 rlekkkafgslkkeseeqrFyFdteegvllpGetrnikvlFksrkvgifkerWeLrthPsllggaslqvrLhGvctaedrekleerkqlekelaqr 378 ++++ ++ g++ ++qrFyFdt++gv+l G+t n+ ++Fks ++gif+e+WeL t+P l+gga + + L+Gv++++d + +e r+++e+ela+r FUN_001841-T2 479 NIPRANSLGTK-LAGRTQRFYFDTKSGVILSGDTLNFPFVFKSPNAGIFTETWELMTKPILCGGAPIRIHLRGVAVEDD-IYKEARQRIEEELARR 572 *********98.55667**************************************************************.**************** PP MYCBPAP 379 eaetkvrsllaellpgvetperpksPyerylteeelFnakNpplyyreddveaLkeLykqv 439 ea+++ +++l+e+l+gv+tper++sP+++y+teee+F + N +y++ + v++Lk++y q+ FUN_001841-T2 573 EAVETAARILNEILDGVRTPERARSPVDAYITEEEIFGRVNEGMYFQDEIVQELKQIYAQL 633 *****************************************99***************985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (855 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1631 (0.0638481); expected 510.9 (0.02) Passed bias filter: 907 (0.035506); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.44u 0.39s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 8089.72 // Query: FUN_001842-T1 [L=516] Description: FUN_001842 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-66 224.8 0.0 1.7e-66 224.3 0.0 1.2 1 MH2 MH2 domain 2e-40 137.6 0.2 3.8e-40 136.7 0.2 1.5 1 MH1 MH1 domain Domain annotation for each model (and alignments): >> MH2 MH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 224.3 0.0 1.3e-70 1.7e-66 1 173 [] 292 493 .. 292 493 .. 0.95 Alignments for each domain: == domain 1 score: 224.3 bits; conditional E-value: 1.3e-70 MH2 1 eiWckiayyElnervgeafkvsss.vsvtvdGstdpsdgerfcLgllsnvnrnekvekvrkkigkGvklsleeegevwiknlsdspvfVqsptldr 95 e+Wc+i+y+El+++vge+fkv ss +sv vdG++dps+g+rfcLg+lsnv+r++++ek+r +igkGv+l l++eg+vw+++ls+++vfVqs++ldr FUN_001842-T1 292 ENWCSISYFELDQQVGEIFKVMSScPSVKVDGYVDPSGGSRFCLGQLSNVHRTDASEKARLHIGKGVQLDLRGEGDVWVRCLSEHSVFVQSYYLDR 387 68********************************************************************************************** PP MH2 96 eagrel.dtvhklppeeslkvFdlekfaklleqeekavalepvdae............................lcsvriSfvKgwGeeysrqdit 162 eagr + d+vhk++p++ +kvFdl++++++++q +++ a+++ +a+ lc++r+SfvKgwG++y+r++i+ FUN_001842-T1 388 EAGRCPgDAVHKIYPSAYIKVFDLRQCYHQIKQ-QAHAAQAAAAAQaaaistgvgpgalipqigmsvgvddlrrLCILRLSFVKGWGPDYPRKSIK 482 **99999********99***************9.44444444444467899********************************************* PP MH2 163 stPcWleihlh 173 +tPcW+eihlh FUN_001842-T1 483 ETPCWVEIHLH 493 *********98 PP >> MH1 MH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 136.7 0.2 3e-44 3.8e-40 2 103 .] 74 174 .. 73 174 .. 0.98 Alignments for each domain: == domain 1 score: 136.7 bits; conditional E-value: 3e-44 MH1 2 kkavesLlkklkkkkeeleelleaveskgkkktkCvliprsldgrlqvaqrkglphvilcrlfrwpdlqskselkaletcesaeeskkeevCvnPy 97 k+a+esL+kklk+k++el++l++a++s g++++kCv+i+r+ldgrlqva rkg+phvi++r++rwpdl+ k+elk+++ c++a+++k ++vCvnPy FUN_001842-T1 74 KRAIESLVKKLKEKRDELDSLITAITSGGTHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLH-KNELKHVKYCQFAFDLKCDSVCVNPY 168 789*****************************************************************5.8************************* PP MH1 98 Hysrvv 103 Hy+rvv FUN_001842-T1 169 HYERVV 174 ****96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (516 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 975 (0.0381679); expected 510.9 (0.02) Passed bias filter: 862 (0.0337444); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.40u 0.36s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4977.71 // Query: FUN_001844-T1 [L=110] Description: FUN_001844 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.062 13.5 0.9 0.35 11.0 0.1 1.9 2 TPR_DOP1_M DOP1 middle TPR domain Domain annotation for each model (and alignments): >> TPR_DOP1_M DOP1 middle TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.1 0.0087 2.2e+02 99 128 .. 6 35 .. 3 42 .. 0.80 2 ? 11.0 0.1 1.4e-05 0.35 104 140 .. 41 79 .. 34 107 .. 0.69 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.0087 TPR_DOP1_M 99 kFilknFnvreeEemvvihlPllllallal 128 F +++ nv+ e e+v P l+ l++ FUN_001844-T1 6 LFTIHHQNVKLEKEVVCLSFPCELVGELVI 35 6999*************9999988765554 PP == domain 2 score: 11.0 bits; conditional E-value: 1.4e-05 TPR_DOP1_M 104 nFnvreeEemvvihlPllllallall..seekeleelsk 140 ++ v+ eE vvih+P l+ +++++l ++++e+++ + FUN_001844-T1 41 SYGVAYEERFVVIHVPCLTSTIVVMLlvNSNSEVRNCFR 79 678999************999998852133444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 664 (0.0259933); expected 510.9 (0.02) Passed bias filter: 369 (0.0144451); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1118.56 // Query: FUN_001845-T1 [L=1652] Description: FUN_001845 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-29 101.7 0.0 1.2e-28 100.4 0.0 1.7 1 SpoU_methylase SpoU rRNA Methylase family 8.6e-07 29.0 1.1 7.2e-06 26.0 1.1 2.3 1 TARBP1 TARBP1 domain Domain annotation for each model (and alignments): >> SpoU_methylase SpoU rRNA Methylase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.4 0.0 9.8e-33 1.2e-28 2 141 .. 1498 1639 .. 1497 1640 .. 0.89 Alignments for each domain: == domain 1 score: 100.4 bits; conditional E-value: 9.8e-33 SpoU_methylase 2 lvvvldeiedpgNlGaiiRtaaafgvdelvlveprsadllnkkvlrasagaleklplvkv..knleealkelkeeglavvatsl..kakslee 90 l+vv i ++ NlG ++Rt+++fgv++lvl + ++ + + +++ s+ a+++++++ v ++l +l+ +++eg++++++++ ++k l++ FUN_001845-T1 1498 LIVVASLIDKAPNLGGLCRTCEIFGVQTLVLGN-IHV-IEDAQFKSLSVSAAKWMNIEDVrtSELTSYLESMRHEGYTLIGVEQtaNSKILTN 1588 899****************************66.555.6777777777777777776555338999******************87888888* PP SpoU_methylase 91 idlkkkvalvlGnEgeGlseevlekadelvkIpmsgeveSLNvavAaaill 141 +++++k +l+lGnE+eG++ e+++k+d +v+Ip+ g ++SLNv+v++a+l+ FUN_001845-T1 1589 YEFPEKSLLLLGNEKEGIPVELIQKLDACVEIPQVGIIRSLNVHVSGALLV 1639 ***********************************************9986 PP >> TARBP1 TARBP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 1.1 5.7e-10 7.2e-06 60 139 .. 272 353 .. 255 415 .. 0.80 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 5.7e-10 TARBP1 60 mqlrveyLlkrivaltkeqelkekldkvvefhplfvWveavs...etqWelffLvlealneyGlhiiePvlaklDalveklaa 139 ++r yLlkr ++ + + ++ + + +++f+W +++W+ + L +e+l+e hii+Pvl+++ ++ ++ ++ FUN_001845-T1 272 TRKRTMYLLKRALDVLDKWPCDLQVM-SERGNNIFYWSSDHTeslRSTWQDYILFMETLDEKQAHIIKPVLTRISSVKDATKK 353 567999***********999999987.556799****95443125789*************************9887655443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1652 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 997 (0.0390292); expected 510.9 (0.02) Passed bias filter: 768 (0.0300646); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.53u 0.42s 00:00:00.95 Elapsed: 00:00:00.44 # Mc/sec: 15276.79 // Query: FUN_001845-T2 [L=1425] Description: FUN_001845 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-29 101.9 0.0 1e-28 100.7 0.0 1.7 1 SpoU_methylase SpoU rRNA Methylase family 6.5e-07 29.4 1.2 5.3e-06 26.4 0.1 2.4 2 TARBP1 TARBP1 domain Domain annotation for each model (and alignments): >> SpoU_methylase SpoU rRNA Methylase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.7 0.0 8e-33 1e-28 2 141 .. 1271 1412 .. 1270 1413 .. 0.89 Alignments for each domain: == domain 1 score: 100.7 bits; conditional E-value: 8e-33 SpoU_methylase 2 lvvvldeiedpgNlGaiiRtaaafgvdelvlveprsadllnkkvlrasagaleklplvkv..knleealkelkeeglavvatsl..kakslee 90 l+vv i ++ NlG ++Rt+++fgv++lvl + ++ + + +++ s+ a+++++++ v ++l +l+ +++eg++++++++ ++k l++ FUN_001845-T2 1271 LIVVASLIDKAPNLGGLCRTCEIFGVQTLVLGN-IHV-IEDAQFKSLSVSAAKWMNIEDVrtSELTSYLESMRHEGYTLIGVEQtaNSKILTN 1361 899****************************66.555.6777777777777777776555338999******************87888888* PP SpoU_methylase 91 idlkkkvalvlGnEgeGlseevlekadelvkIpmsgeveSLNvavAaaill 141 +++++k +l+lGnE+eG++ e+++k+d +v+Ip+ g ++SLNv+v++a+l+ FUN_001845-T2 1362 YEFPEKSLLLLGNEKEGIPVELIQKLDACVEIPQVGIIRSLNVHVSGALLV 1412 ***********************************************9986 PP >> TARBP1 TARBP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.1 4.1e-10 5.3e-06 60 136 .. 45 123 .. 29 132 .. 0.81 2 ? 2.0 0.1 0.012 1.6e+02 154 207 .. 122 175 .. 118 188 .. 0.77 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 4.1e-10 TARBP1 60 mqlrveyLlkrivaltkeqelkekldkvvefhplfvWveavs...etqWelffLvlealneyGlhiiePvlaklDalvek 136 ++r yLlkr ++ + + ++ + + +++f+W +++W+ + L +e+l+e hii+Pvl+++ ++ ++ FUN_001845-T2 45 TRKRTMYLLKRALDVLDKWPCDLQVM-SERGNNIFYWSSDHTeslRSTWQDYILFMETLDEKQAHIIKPVLTRISSVKDA 123 567999***********999999987.556799****95443125789*************************9887555 PP == domain 2 score: 2.0 bits; conditional E-value: 0.012 TARBP1 154 eaaisvlslkgalhpaWvelLllklllhPnlavrkvgLrrlWslsasvlkllss 207 +a+++ ++ ++ l++ Wv L k+ +h n + + +L l s++ lls+ FUN_001845-T2 122 DATKKAPNGVTMLDSSWVLTLYHKAAMHDNRFICRWALLDLLSVDLDSSPLLST 175 4555667778899******************99999999999987655555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1425 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 740 (0.0289685); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.45u 0.44s 00:00:00.89 Elapsed: 00:00:00.42 # Mc/sec: 13623.57 // Query: FUN_001845-T3 [L=1063] Description: FUN_001845 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-07 30.1 1.5 5.2e-06 26.4 1.5 2.4 1 TARBP1 TARBP1 domain Domain annotation for each model (and alignments): >> TARBP1 TARBP1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 1.5 2e-10 5.2e-06 60 139 .. 45 126 .. 28 188 .. 0.80 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 2e-10 TARBP1 60 mqlrveyLlkrivaltkeqelkekldkvvefhplfvWveavs...etqWelffLvlealneyGlhiiePvlaklDalveklaa 139 ++r yLlkr ++ + + ++ + + +++f+W +++W+ + L +e+l+e hii+Pvl+++ ++ ++ ++ FUN_001845-T3 45 TRKRTMYLLKRALDVLDKWPCDLQVM-SERGNNIFYWSSDHTeslRSTWQDYILFMETLDEKQAHIIKPVLTRISSVKDATKK 126 567999***********999999987.556799****95443125789*************************9887655443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1063 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1048 (0.0410256); expected 510.9 (0.02) Passed bias filter: 807 (0.0315913); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.44u 0.40s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 10159.16 // Query: FUN_001846-T1 [L=550] Description: FUN_001846 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-147 492.6 30.5 2.8e-147 492.1 30.5 1.2 1 SNF Sodium:neurotransmitter symporter family ------ inclusion threshold ------ 0.058 14.1 0.6 0.058 14.1 0.6 4.5 5 Spore_YabQ Spore cortex protein YabQ Domain annotation for each model (and alignments): >> SNF Sodium:neurotransmitter symporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 492.1 30.5 2.2e-151 2.8e-147 36 523 .. 13 523 .. 7 524 .. 0.94 Alignments for each domain: == domain 1 score: 492.1 bits; conditional E-value: 2.2e-151 SNF 36 GGafliPYlilllvaGiPlfflelalGqytreGaitvwrkicPlfkgiGyasivialyvglyYnvilawalyYlfssftteLpWaeCnnswnteeC 131 GafliPY+ l++ GiPlfflela+Gq +r+G i+vwr i P + g+G as+v +l+v++yYn+i+aw ++Ylf sf++ Lp+++C ++C FUN_001846-T1 13 SGAFLIPYFTSLVLLGIPLFFLELAIGQSIRQGPIGVWRAIHPYLGGVGVASAVACLLVAMYYNMIIAWCFFYLFVSFQDPLPYSSCPL---GPNC 105 59*************************************************************************************74...6899 PP SNF 132 vealakenssaassenltektspaeefferkvlklskgieelGelrwelalcllvalvvvylsilkGvkssgkvvyftatfPyvvllvllvrgvtL 227 + +e + l + +++f++ k l ++ie++Ge +w+l+l+l++a+ ++yl + +Gv+s+gk vy+tat+Py+vl++++ r+vtL FUN_001846-T1 106 TT---NEGC------IL---AGRTQYFWYTKTLGAASSIEKMGEFQWHLCLVLFLAWALLYLFVSRGVRSVGKAVYITATLPYIVLAIFFGRAVTL 189 54...2222......22...36789*********************************************************************** PP SNF 228 pGavkgikfyltpdlekllepkvWidaatqiffslgigfGvlialasYnkfennvyrdallvslinsltsvlagfviFsvlGfmaqeqgve..... 318 +G+++gi ++++p++++ll+p vW++a tq+ffs+g+gfG+lia++sYn+ +nn+ rda+++sl++s+tsv+a++v+Fs+lGf+a+++ e FUN_001846-T1 190 KGSLDGIIHMFKPEFSRLLSPIVWLEAVTQVFFSVGVGFGTLIAMSSYNHIHNNCKRDAIFISLTDSFTSVFAAVVVFSMLGFKAHNSYDEclaly 285 ***************************************************************************************999978888 PP SNF 319 ..................isevaee..........GpgLaFiaypeavtklplsplwsvlFFlmllllgldsqfavveglitalvDefkvllrkrr 386 + GpgL Fia++ea+ klplsp wsvl F+mll lgl+s+f+++eg + +l ++ + r+ FUN_001846-T1 286 ggvnntnlpsgvtlqekcH-----NlthwlsesfqGPGLTFIAFTEAILKLPLSPAWSVLLFCMLLSLGLGSMFGILEGALNSLHEQKLI--PLRK 374 8877777777766555550.....15555555666*************************************************987655..457* PP SNF 387 ellvlivvvlaflvglllvtegGiyvlelldkyaaslsllvvalleaiavawvyglkrflddikemlgfrpglflklcwklvspllllalliasiv 482 e+l+ + +++++ vg l+++++G y+l+++d+++a+l+llv+ ++e+++v+w+yg++rf+ddi+ ml rp++++k++w++vspl++l++++ s+ FUN_001846-T1 375 EILTGLTCCVCMAVGALFCQTSGEYWLQMFDSFSATLPLLVICFFELVGVSWIYGANRFYDDIEYMLRVRPCWYWKVTWRFVSPLIVLVIFVCSLL 470 ***********************************************************************************************9 PP SNF 483 ky..kpltyekyv..........yPkwaealgwllalssvvviplvvilklls 523 ++ kp ty++++ yP+w + + +l+ +s+++ip+v++l+l++ FUN_001846-T1 471 NMgmKPVTYSAWRenkgdvksmaYPTWCYFIIGSLICASCLCIPAVFMLRLFQ 523 98779*******************************************99875 PP >> Spore_YabQ Spore cortex protein YabQ # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 1.3 0.54 6.9e+03 37 52 .. 73 88 .. 59 92 .. 0.62 2 ? -0.6 0.1 0.18 2.3e+03 56 78 .. 135 157 .. 130 158 .. 0.80 3 ? -3.4 0.2 1.3 1.7e+04 62 70 .. 176 184 .. 173 187 .. 0.81 4 ? 14.1 0.6 4.5e-06 0.058 2 52 .. 221 271 .. 220 277 .. 0.94 5 ? 2.6 0.1 0.018 2.2e+02 1 52 [. 340 391 .. 340 401 .. 0.85 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 0.54 Spore_YabQ 37 ilfwllaalivfyvll 52 + + +++a ++fy+++ FUN_001846-T1 73 MYYNMIIAWCFFYLFV 88 4555666666666554 PP == domain 2 score: -0.6 bits; conditional E-value: 0.18 Spore_YabQ 56 egevrlYvflglllGlllYflll 78 ge+++++ l+l+l ++l +l++ FUN_001846-T1 135 MGEFQWHLCLVLFLAWALLYLFV 157 58999999999999988877766 PP == domain 3 score: -3.4 bits; conditional E-value: 1.3 Spore_YabQ 62 YvflglllG 70 Y++l++++G FUN_001846-T1 176 YIVLAIFFG 184 999999998 PP == domain 4 score: 14.1 bits; conditional E-value: 4.5e-06 Spore_YabQ 2 lasvllGivlgllfdlyrvirkllrlkkiltaieDilfwllaalivfyvll 52 ++sv++G+ + ++ + y+ i + +++ i+ + D + ++aa++vf +l FUN_001846-T1 221 FFSVGVGFGTLIAMSSYNHIHNNCKRDAIFISLTDSFTSVFAAVVVFSMLG 271 68999*******************************************995 PP == domain 5 score: 2.6 bits; conditional E-value: 0.018 Spore_YabQ 1 llasvllGivlgllfdlyrvirkllrlkkiltaieDilfwllaalivfyvll 52 ll+++ll + lg +f +++ ++ l+ +k++ +il l +++++ + l FUN_001846-T1 340 LLFCMLLSLGLGSMFGILEGALNSLHEQKLIPLRKEILTGLTCCVCMAVGAL 391 57889999999****************9*99999999999999988877655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (550 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 927 (0.0362889); expected 510.9 (0.02) Passed bias filter: 441 (0.0172637); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 5517.90 // Query: FUN_001847-T1 [L=504] Description: FUN_001847 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-164 546.5 28.5 1.5e-163 545.8 28.5 1.3 1 SNF Sodium:neurotransmitter symporter family Domain annotation for each model (and alignments): >> SNF Sodium:neurotransmitter symporter family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 545.8 28.5 5.8e-168 1.5e-163 1 444 [. 52 504 .] 52 504 .] 0.94 Alignments for each domain: == domain 1 score: 545.8 bits; conditional E-value: 5.8e-168 SNF 1 RetwskkldfllsvvGfavgLgnvWRFPYlcyknGGGafliPYlilllvaGiPlfflelalGqytreGaitvwrkicPlfkgiGyasivialyvgl 96 R++w+++++f+l+++GfavgLgnvWRFPYlc+knGGGafliPY++ l++ GiPlfflela+Gq r+G+++vw+ i P + g+Gya +v++++vg+ FUN_001847-T1 52 RGKWGNQIEFVLAAIGFAVGLGNVWRFPYLCQKNGGGAFLIPYFMSLFLLGIPLFFLELAIGQSLRQGSVGVWNAIHPYLGGLGYACVVVCILVGM 147 89********************************************************************************************** PP SNF 97 yYnvilawalyYlfssftteLpWaeCnnswnteeCvealakenssaassenltektspaeefferkvlklskgieelGelrwelalcllvalvvvy 192 yYn+i++w +yYlf+sf++ Lp+++C + n e + +++ +++++++ k+l++s++iee G + w+l+++llva++vv+ FUN_001847-T1 148 YYNMIISWCFYYLFASFQNPLPYSSCPRDLNGTLLEE------C---------KEAGSTQYYWYSKALNVSSSIEEGGGVMWHLVMVLLVAWTVVF 228 **************************98887654422......1.........23356789*********************************** PP SNF 193 lsilkGvkssgkvvyftatfPyvvllvllvrgvtLpGavkgikfyltpdlekllepkvWidaatqiffslgigfGvlialasYnkfennvyrdall 288 l++++Gv+s+gk vyftatfPy+vl++++ rgv L+Ga g+ ++++p+++kl +p+vW++aatqiffsl+++fG+lia++sYn +nn++rda++ FUN_001847-T1 229 LCMMRGVQSAGKAVYFTATFPYLVLTIFFGRGVSLEGAGAGVAYMFKPQFSKLANPQVWLEAATQIFFSLSVAFGGLIAMSSYNPVHNNCHRDAIV 324 ************************************************************************************************ PP SNF 289 vslinsltsvlagfviFsvlGfmaqeqgve.......isevaee........................GpgLaFiaypeavtklplsplwsvlFFl 353 vslin+ ts++a++viF +lGf a+++ +e + GpgL Fia++ea+ +p+sp+wsvlFF+ FUN_001847-T1 325 VSLINCGTSIFASIVIFCILGFRATTSLNEcqefwvnK-----TdingtdlvkehchdleywlsqsasGPGLTFIAFTEAIVRMPASPIWSVLFFC 415 **************************999945555550.....2555555555556667777777777**************************** PP SNF 354 mllllgldsqfavveglitalvDefkvllrkrrellvlivvvlaflvglllvtegGiyvlelldkyaaslsllvvalleaiavawvyglkr 444 mll+lg++s+f+++eg+it+ D+ v r+e+++++++ ++fl+g+++++++G y+l+++d+y a+l+ll++ ++e+++v+++y+++r FUN_001847-T1 416 MLLTLGMGSMFGTLEGVITPFYDMKIV--PFRKEIMTAMICGFCFLCGIIFTQQSGQYWLQMFDNYCATLPLLLIGFCELVGVSYIYKIER 504 ***********************8766..457*******************************************************9975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (504 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1126 (0.0440791); expected 510.9 (0.02) Passed bias filter: 603 (0.0236054); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4851.44 // Query: FUN_001848-T1 [L=617] Description: FUN_001848 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-53 180.5 2.3 5.8e-25 88.2 0.0 3.3 3 CUB CUB domain ------ inclusion threshold ------ 0.033 14.5 0.3 1.7 9.0 0.0 3.1 3 CUB_2 CUB-like domain 0.15 13.2 0.0 0.56 11.4 0.0 1.9 1 WBP-1 WW domain-binding protein 1 Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.6 0.1 1.8e-13 1.5e-09 1 102 [. 40 150 .. 40 153 .. 0.80 2 ! 52.2 0.1 1.1e-17 9.2e-14 9 103 .. 173 268 .. 164 277 .. 0.82 3 ! 88.2 0.0 6.8e-29 5.8e-25 9 110 .] 304 408 .. 292 408 .. 0.92 Alignments for each domain: == domain 1 score: 38.6 bits; conditional E-value: 1.8e-13 CUB 1 Cgge.ltessgsisspnypkeYeenkeCvweirvekgksvklkfedfel..eeeeecaydyvevrdgeeas.skllgkfcG.....sekpedikss 87 Cgg+ + ++++sissp yp+ + ++C+w i+ ++gks+ ++ ++++ e +++c + ++++++g +++ l++k+c + ++ ss FUN_001848-T1 40 CGGRvVINKTTSISSPGYPEVSLPGVDCTWWIESSTGKSIIVRGNHLDFgsEIKDDCSKGVLQIFNGCNNKeRFLVEKICLnmqqiERQSILWISS 135 9999999**********************************998886651156677***********99985678899997554332223334577 PP CUB 88 snqllikfvsdesvs 102 + ++ikf+s++ + FUN_001848-T1 136 GPCVTIKFSSEQGRK 150 888888888887665 PP == domain 2 score: 52.2 bits; conditional E-value: 1.1e-17 CUB 9 sgsisspnypkeYeenkeCvweirvekgksvklkfed.feleeeee.caydyvevrdgeeasskllgkfcGsekpediksssnqllikfvsdesvs 102 + + + p++ + +++Cvw i v+kg+ ++l f+d f + + ++ c+ +yv v+dg+ ++s++lgkfcG+++p ++ s ++ l ++++s+++ FUN_001848-T1 173 RNHTFTGSLPANPSIHNKCVWIIGVQKGN-IELVFQDkFHVTSLQKdCRENYVLVQDGRYSTSPTLGKFCGTSRPYPVYSGGQYLRVTLHSSNTGV 267 34444566788888999**********98.******99**9986666********************************************98765 PP CUB 103 k 103 + FUN_001848-T1 268 N 268 4 PP == domain 3 score: 88.2 bits; conditional E-value: 6.8e-29 CUB 9 sgsisspnypkeYeenkeCvweirvekgksvklkfedfeleeeee.ca..ydyvevrdgeeasskllgkfcGsekpediksssnqllikfvsdesv 101 gs+++p+yp +Y+++ +C+w+i+v +++++ l+f+df++e +++ c d+ +v++g + s+++g++cG+e p+ i+s+ n l i+f s+++ FUN_001848-T1 304 GGSFQTPRYPVQYPRDLDCIWKIEVAQNNKIILRFRDFDVEGDSQdCPddSDHAKVYNGLASWSPIIGRYCGKETPSSITSKANVLRIEFRSNAQY 399 589**************************************887778622679******************************************* PP CUB 102 skkGFkaty 110 +GF+a y FUN_001848-T1 400 AGRGFHAVY 408 ******988 PP >> CUB_2 CUB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.034 2.9e+02 6 49 .. 40 72 .. 37 129 .. 0.78 2 ? -1.5 0.0 0.33 2.8e+03 41 53 .. 188 200 .. 174 228 .. 0.76 3 ? 9.0 0.0 0.0002 1.7 4 60 .. 290 338 .. 287 357 .. 0.78 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.034 CUB_2 6 CksgtvtinkpangsipvyYPetwnesaelpkipanqnCsynin 49 C g v+ink+ ++s+p YPe+ ++ +C++ i+ FUN_001848-T1 40 C-GGRVVINKTTSISSP-GYPEV---------SLPGVDCTWWIE 72 8.889999999999999.89988.........456778888776 PP == domain 2 score: -1.5 bits; conditional E-value: 0.33 CUB_2 41 nqnCsyninvPkg 53 +C ++i v kg FUN_001848-T1 188 HNKCVWIIGVQKG 200 4689999999887 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0002 CUB_2 4 ltCksgtvtinkpangsipvyYPetwnesaelpkipanqnCsyninvPkgyyakvti 60 +Ck g + ++p+ gs ++++p + +C ++i+v ++ + +++ FUN_001848-T1 290 SDCKDGDIFLKDPNGGSFQ--------TPRYPVQYPRDLDCIWKIEVAQNNKIILRF 338 6788888887777666555........23469***************9998777766 PP >> WBP-1 WW domain-binding protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 6.5e-05 0.56 30 84 .. 434 488 .. 423 504 .. 0.86 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 6.5e-05 WBP-1 30 llillsCccalakrraelrleqqrrereinlvayreaknaaslpldarllasakl 84 ++ +++C+ a+ ++r++++ +++r e ++a+ ++++a ++p +a+++as +l FUN_001848-T1 434 IIFIVLCFLAVVHTRKHRFQRAHSRPSELASTASFDVHEANAPPSYATVMASPEL 488 7899***************9**************99******9999999887554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (617 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 747 (0.0292425); expected 510.9 (0.02) Passed bias filter: 660 (0.0258368); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.43s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 6021.56 // Query: FUN_001849-T1 [L=87] Description: FUN_001849 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (87 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1128 (0.0441574); expected 510.9 (0.02) Passed bias filter: 548 (0.0214523); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 871.93 // Query: FUN_001850-T1 [L=1129] Description: FUN_001850 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-44 150.7 2.9 1.2e-43 149.8 2.9 1.5 1 NIDO Nidogen-like 4.9e-21 75.4 6.6 2.6e-08 34.6 0.1 3.7 3 Sushi Sushi repeat (SCR repeat) 2.2e-12 48.0 0.0 8.8e-12 46.1 0.0 2.1 2 VWD von Willebrand factor type D domain 4.4e-10 39.2 0.0 1.1e-09 37.9 0.0 1.7 1 C8-3_MUC4 Mucin-4-like C8-3 domain 7.6e-07 29.8 2.4 1.5e-06 28.8 2.4 1.6 1 AMOP AMOP domain ------ inclusion threshold ------ 0.054 13.6 0.0 0.12 12.4 0.0 1.5 1 SUR7 SUR7/PalI family 0.072 12.7 0.4 1.2 8.6 0.4 2.7 1 RGM_C Repulsive guidance molecule (RGM) C-terminal do 0.21 11.7 0.2 0.38 10.8 0.2 1.4 1 Peripla_BP_6 Periplasmic binding protein 0.9 9.9 3.7 2.6 8.5 0.3 2.8 2 cEGF Complement Clr-like EGF-like Domain annotation for each model (and alignments): >> NIDO Nidogen-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 149.8 2.9 4.1e-47 1.2e-43 3 185 .. 64 248 .. 62 249 .. 0.97 Alignments for each domain: == domain 1 score: 149.8 bits; conditional E-value: 4.1e-47 NIDO 3 lyvntnGivsfseplsqylpekfplsf..pmiApfladvdtrdgrgkvyyredsspevlqraeedirrafpeaeefkatsvlvvTWenVaaygsqs 96 l vn+nGi+ f + s+ p +fpl++ + Ap++adv t++g g+++yr +s++ ++ +++di+rafp+ +ef+ +++++vTW+ V+++ ++ FUN_001850-T1 64 LHVNENGIIFFGAVSSDKSPSTFPLRDkvYAAAPYWADVFTERG-GNIWYRLTSDNVTMYAITRDIKRAFPRYNEFTSSWAVIVTWDGVTFFSATD 158 679*************999*******878899************.******999999*************************************99 PP NIDO 97 r..kktNTFQlvlasdesesyaiflYpedglqwttte...gkknglggapaqaGFsagdgtryynlpgseessvrnltessnvgvpGvwvfrig 185 +k+NTFQ++++s+++ s++ lY ++l wtt++ g+++glgg+pa++GFs gd y++++ s++++v lt+++n+g+pGv++fr++ FUN_001850-T1 159 AytRKKNTFQVIMTSNGNMSFVAYLY--KKLVWTTGTlngGNQSGLGGKPARIGFSYGDW--YHEIEDSGTKNVLTLTKNTNCGQPGVFFFRVD 248 9999**********************..***********99******************9..******************************98 PP >> Sushi Sushi repeat (SCR repeat) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.2 4.5e-09 1.3e-05 26 56 .] 924 953 .. 900 953 .. 0.76 2 ! 34.6 0.1 9.3e-12 2.6e-08 1 56 [] 960 1014 .. 960 1014 .. 0.93 3 ! 16.7 0.3 3.7e-06 0.011 24 56 .] 1036 1067 .. 1019 1067 .. 0.84 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 4.5e-09 Sushi 26 eyeCdpGyrlvgsptitCqedgtWsseepeC 56 ++C++Gy+l g++ti C dg W++++p+C FUN_001850-T1 924 YFKCNEGYVLFGQDTISC-RDGVWDGSAPRC 953 579***************.9999******** PP == domain 2 score: 34.6 bits; conditional E-value: 9.3e-12 Sushi 1 Cppppd.lpngkvsatkeeynvgakveyeCdpGyrlvgsptitCqedgtWsseepeC 56 C+p+ + l+ng++++ + ++g+++++ Cd ++lvg+ ++ C +dg Ws+ +p+C FUN_001850-T1 960 CKPLDAsLSNGSFHG--DGNKFGDRYTFDCDATFVLVGNREVICGKDGVWSGIVPTC 1014 66666668999***9..9*************************************** PP == domain 3 score: 16.7 bits; conditional E-value: 3.7e-06 Sushi 24 kveyeCdpGyrlvgsptitCqedgtWsseepeC 56 ++ ++C++Gy l g+ +i C e+g+ +++ p C FUN_001850-T1 1036 VLVISCNEGYSLTGPGKINC-ENGSLNGTSPSC 1067 5789****************.***999999999 PP >> VWD von Willebrand factor type D domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.1 0.0 3.1e-15 8.8e-12 3 155 .. 623 787 .. 621 788 .. 0.78 2 ? -3.3 0.0 4.9 1.4e+04 14 30 .. 980 996 .. 980 1004 .. 0.87 Alignments for each domain: == domain 1 score: 46.1 bits; conditional E-value: 3.1e-15 VWD 3 vsgdphykTFDglkytfpgtctYvlakdcseesdfsvsvtnkkenegaeevt....clksvkvkvgeqeielkkg...qlkvlvngqkvsl....p 87 ++gdph+ T Dg++ytf+g +Y++ ++ e f ++ +++ ++g+ ++ ++ +++g++ i+++++ +l++g+++ + + FUN_001850-T1 623 LFGDPHFITLDGVEYTFNGYGEYTILNANNAE--FLLQGRMQPLPGGQGVKSpatgFTAFAMMQTGSSRIQVQRDrsqPFVLLIDGKQTIIefgrE 716 69**********************88888888..89999999988888777654445555556666*********996666777888777766655 PP VWD 88 vvkegkeveilssg.fvvvelstgvelqvdgdg..reqlkvtlsqsyqgktcGLCGnyngeqeddfltpdg 155 ++ +g +++ +s+g ++++++++ +++v +++ + q+ vt++ +++gkt+GL G +n++++ ++l+p+g FUN_001850-T1 717 LQAKGVSIRNTSRGeHLRLVIAFICGITVYIEDaaVLQVAVTVPVEFKGKTKGLLGFWNDNTNEEYLLPNG 787 6655667777775513555556666666555554599********************************98 PP == domain 2 score: -3.3 bits; conditional E-value: 4.9 VWD 14 glkytfpgtctYvlakd 30 g++ytf+ + t+vl+ + FUN_001850-T1 980 GDRYTFDCDATFVLVGN 996 789**********9876 PP >> C8-3_MUC4 Mucin-4-like C8-3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 0.0 3.9e-13 1.1e-09 7 48 .. 851 892 .. 848 894 .. 0.92 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 3.9e-13 C8-3_MUC4 7 lleeaaelCggdkfCifDylaTgslsvGnaTlqaeqsfqnlv 48 l++ a ++C+ + +C+fD+++Tg++++G++T++++++ +++ FUN_001850-T1 851 LRKRALRICEQSFQCVFDIAVTGRVDIGKDTMEFQKWLLEMK 892 7899*******************************9988876 PP >> AMOP AMOP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 2.4 5.4e-10 1.5e-06 3 143 .] 475 603 .. 473 603 .. 0.79 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 5.4e-10 AMOP 3 elCekWleedealknfla...elpsCPCtleqallDkgRflpdlecdkeanskceykkgakhcvrsvqpseegagqqCCYdkegkllltsdsvkgs 95 e+C W + + + ++ l+ ++ CP t++q l+D+gRf++ +++ +c+ +k + s++++ ++ +CCYd++g + + FUN_001850-T1 475 ESCLLWKRLQTVNTSQLEghkAVAPCPKTVRQLLADEGRFTSYDVYHHKDAFSCYLHK-----IPSSASFDKSRRSECCYDRDGGIT--------G 557 689999999877777766555889****************876555555556677665.....5566777778899********987........9 PP AMOP 96 tPkrahelGaapykeaekvpelshylvDvlpfylCClwaeeavdcety 143 P+r + + ++a v + ++ ++p+ CC++a +++ c+ y FUN_001850-T1 558 APTRVVANQTKSQNTAASV--FIEFREHLTPYLECCVFAADTDACSAY 603 9**9988777666555554..568****************99***988 PP >> SUR7 SUR7/PalI family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 4.3e-05 0.12 86 136 .. 1059 1112 .. 1032 1118 .. 0.80 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.3e-05 SUR7 86 esngklpsslrdslstyyylsrfmlivhiialvftvialvlgllaif...sssr 136 + ng+ ps +r + st ++ +v+iia++++++al+++ ++i+ +++r FUN_001850-T1 1059 SLNGTSPSCIRGKSSTAHARQEAFTAVLIIAAAVSFVALLIIAITIClvcKHRR 1112 334448999999****9999*********************9999996666655 PP >> RGM_C Repulsive guidance molecule (RGM) C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 0.4 0.00042 1.2 6 158 .. 622 787 .. 619 892 .. 0.59 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00042 RGM_C 6 glfGDPHlrtfkdefqtCkvegawPlid..neyllvqvtnkpvvegssatavtkitviikelkeCtdqkvYeAetddlpaaFvDGtts...sgeke 96 +lfGDPH t+++ t + g + +++ n+ +l q +p+ g + + + + +++ +++ + + ++ +DG ++ g++ FUN_001850-T1 622 ALFGDPHFITLDGVEYTFNGYGEYTILNanNAEFLLQGRMQPLPGGQGVKSPATGFTAFAMMQTGSSRIQVQRDRSQPFVLLIDGKQTiieFGREL 717 79***********999*9999999998533777889999999987765444333333455555444444444455555556788876522246666 PP RGM_C 97 gkkslevlekepgrhveiaakyi.gttivvRqvgryLslavrlpeeva........ealeeeqdlqlCvaG 158 ++k ++++++++g+h+ + +++i g t+++ + L +av++p e+ ++++++++l +G FUN_001850-T1 718 QAKGVSIRNTSRGEHLRLVIAFIcGITVYI-EDAAVLQVAVTVPVEFKgktkgllgFWNDNTNEEYLLPNG 787 788999**9999******999994456666.5567899999999988744444433333344445555555 PP >> Peripla_BP_6 Periplasmic binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.2 0.00013 0.38 89 160 .. 66 133 .. 64 177 .. 0.91 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00013 Peripla_BP_6 89 lakkgvpvigpsgltgekcspnvfslgpttsaqaaalvdylakelggkkvaligadyafgraleaaakaalk 160 ++++g++++g++++ + sp +f+l+ +a a ++d +++e+gg+ ++ +++d+ a+++++k+a+ FUN_001850-T1 66 VNENGIIFFGAVSS---DKSPSTFPLRDKVYAAAPYWAD-VFTERGGNIWYRLTSDNVTMYAITRDIKRAFP 133 67889999987544...479*******************.58889***********************9986 PP >> cEGF Complement Clr-like EGF-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.3 0.14 3.8e+02 6 21 .. 927 943 .. 926 944 .. 0.68 2 ? 8.5 0.3 0.0009 2.6 5 17 .. 1040 1052 .. 1040 1056 .. 0.83 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.14 cEGF 6 CppGYtLa.gDGrtCvD 21 C++GY L D +C D FUN_001850-T1 927 CNEGYVLFgQDTISCRD 943 *****985335566666 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0009 cEGF 5 sCppGYtLagDGr 17 sC++GY+L+g G+ FUN_001850-T1 1040 SCNEGYSLTGPGK 1052 8********9995 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 756 (0.0295948); expected 510.9 (0.02) Passed bias filter: 640 (0.0250538); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.47u 0.41s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 10648.47 // Query: FUN_001850-T2 [L=964] Description: FUN_001850 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-44 150.9 2.9 9.2e-44 150.1 2.9 1.4 1 NIDO Nidogen-like 2.3e-12 48.0 0.0 6.9e-12 46.4 0.0 1.9 1 VWD von Willebrand factor type D domain 3.6e-10 39.5 0.0 9.2e-10 38.2 0.0 1.7 1 C8-3_MUC4 Mucin-4-like C8-3 domain 6e-07 30.2 2.3 1.2e-06 29.2 2.3 1.6 1 AMOP AMOP domain 4.3e-06 27.5 0.2 1.1e-05 26.3 0.2 1.7 1 Sushi Sushi repeat (SCR repeat) ------ inclusion threshold ------ 0.049 13.2 0.5 0.99 8.9 0.5 2.8 1 RGM_C Repulsive guidance molecule (RGM) C-terminal do 0.17 12.0 0.2 0.31 11.1 0.2 1.4 1 Peripla_BP_6 Periplasmic binding protein Domain annotation for each model (and alignments): >> NIDO Nidogen-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 150.1 2.9 2.5e-47 9.2e-44 3 185 .. 64 248 .. 62 249 .. 0.97 Alignments for each domain: == domain 1 score: 150.1 bits; conditional E-value: 2.5e-47 NIDO 3 lyvntnGivsfseplsqylpekfplsf..pmiApfladvdtrdgrgkvyyredsspevlqraeedirrafpeaeefkatsvlvvTWenVaaygsqs 96 l vn+nGi+ f + s+ p +fpl++ + Ap++adv t++g g+++yr +s++ ++ +++di+rafp+ +ef+ +++++vTW+ V+++ ++ FUN_001850-T2 64 LHVNENGIIFFGAVSSDKSPSTFPLRDkvYAAAPYWADVFTERG-GNIWYRLTSDNVTMYAITRDIKRAFPRYNEFTSSWAVIVTWDGVTFFSATD 158 679*************999*******878899************.******999999*************************************99 PP NIDO 97 r..kktNTFQlvlasdesesyaiflYpedglqwttte...gkknglggapaqaGFsagdgtryynlpgseessvrnltessnvgvpGvwvfrig 185 +k+NTFQ++++s+++ s++ lY ++l wtt++ g+++glgg+pa++GFs gd y++++ s++++v lt+++n+g+pGv++fr++ FUN_001850-T2 159 AytRKKNTFQVIMTSNGNMSFVAYLY--KKLVWTTGTlngGNQSGLGGKPARIGFSYGDW--YHEIEDSGTKNVLTLTKNTNCGQPGVFFFRVD 248 9999**********************..***********99******************9..******************************98 PP >> VWD von Willebrand factor type D domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.4 0.0 1.9e-15 6.9e-12 3 155 .. 623 787 .. 621 788 .. 0.78 Alignments for each domain: == domain 1 score: 46.4 bits; conditional E-value: 1.9e-15 VWD 3 vsgdphykTFDglkytfpgtctYvlakdcseesdfsvsvtnkkenegaeevt....clksvkvkvgeqeielkkg...qlkvlvngqkvsl....p 87 ++gdph+ T Dg++ytf+g +Y++ ++ e f ++ +++ ++g+ ++ ++ +++g++ i+++++ +l++g+++ + + FUN_001850-T2 623 LFGDPHFITLDGVEYTFNGYGEYTILNANNAE--FLLQGRMQPLPGGQGVKSpatgFTAFAMMQTGSSRIQVQRDrsqPFVLLIDGKQTIIefgrE 716 69**********************88888888..89999999988888777654445555556666*********996666777888777766655 PP VWD 88 vvkegkeveilssg.fvvvelstgvelqvdgdg..reqlkvtlsqsyqgktcGLCGnyngeqeddfltpdg 155 ++ +g +++ +s+g ++++++++ +++v +++ + q+ vt++ +++gkt+GL G +n++++ ++l+p+g FUN_001850-T2 717 LQAKGVSIRNTSRGeHLRLVIAFICGITVYIEDaaVLQVAVTVPVEFKGKTKGLLGFWNDNTNEEYLLPNG 787 6655667777775513555556666666555554599********************************98 PP >> C8-3_MUC4 Mucin-4-like C8-3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.2 0.0 2.5e-13 9.2e-10 7 48 .. 851 892 .. 848 894 .. 0.92 Alignments for each domain: == domain 1 score: 38.2 bits; conditional E-value: 2.5e-13 C8-3_MUC4 7 lleeaaelCggdkfCifDylaTgslsvGnaTlqaeqsfqnlv 48 l++ a ++C+ + +C+fD+++Tg++++G++T++++++ +++ FUN_001850-T2 851 LRKRALRICEQSFQCVFDIAVTGRVDIGKDTMEFQKWLLEMK 892 7899*******************************9988876 PP >> AMOP AMOP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 2.3 3.4e-10 1.2e-06 3 143 .] 475 603 .. 473 603 .. 0.79 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 3.4e-10 AMOP 3 elCekWleedealknfla...elpsCPCtleqallDkgRflpdlecdkeanskceykkgakhcvrsvqpseegagqqCCYdkegkllltsdsvkgs 95 e+C W + + + ++ l+ ++ CP t++q l+D+gRf++ +++ +c+ +k + s++++ ++ +CCYd++g + + FUN_001850-T2 475 ESCLLWKRLQTVNTSQLEghkAVAPCPKTVRQLLADEGRFTSYDVYHHKDAFSCYLHK-----IPSSASFDKSRRSECCYDRDGGIT--------G 557 689999999877777766555889****************876555555556677665.....5566777778899********987........9 PP AMOP 96 tPkrahelGaapykeaekvpelshylvDvlpfylCClwaeeavdcety 143 P+r + + ++a v + ++ ++p+ CC++a +++ c+ y FUN_001850-T2 558 APTRVVANQTKSQNTAASV--FIEFREHLTPYLECCVFAADTDACSAY 603 9**9988777666555554..568****************99***988 PP >> Sushi Sushi repeat (SCR repeat) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.2 2.9e-09 1.1e-05 26 56 .] 924 953 .. 900 953 .. 0.76 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 2.9e-09 Sushi 26 eyeCdpGyrlvgsptitCqedgtWsseepeC 56 ++C++Gy+l g++ti C dg W++++p+C FUN_001850-T2 924 YFKCNEGYVLFGQDTISC-RDGVWDGSAPRC 953 579***************.9999******** PP >> RGM_C Repulsive guidance molecule (RGM) C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.5 0.00027 0.99 6 158 .. 622 787 .. 619 892 .. 0.59 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.00027 RGM_C 6 glfGDPHlrtfkdefqtCkvegawPlid..neyllvqvtnkpvvegssatavtkitviikelkeCtdqkvYeAetddlpaaFvDGtts...sgeke 96 +lfGDPH t+++ t + g + +++ n+ +l q +p+ g + + + + +++ +++ + + ++ +DG ++ g++ FUN_001850-T2 622 ALFGDPHFITLDGVEYTFNGYGEYTILNanNAEFLLQGRMQPLPGGQGVKSPATGFTAFAMMQTGSSRIQVQRDRSQPFVLLIDGKQTiieFGREL 717 79************9**9999999998533777889999999987765444333333455555444444444455555556789876522246666 PP RGM_C 97 gkkslevlekepgrhveiaakyi.gttivvRqvgryLslavrlpeeva........ealeeeqdlqlCvaG 158 ++k ++++++++g+h+ + +++i g t+++ + L +av++p e+ ++++++++l +G FUN_001850-T2 718 QAKGVSIRNTSRGEHLRLVIAFIcGITVYI-EDAAVLQVAVTVPVEFKgktkgllgFWNDNTNEEYLLPNG 787 78899**************99994456666.5667899999999988744444433333344455555555 PP >> Peripla_BP_6 Periplasmic binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.2 8.4e-05 0.31 89 161 .. 66 134 .. 64 179 .. 0.91 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8.4e-05 Peripla_BP_6 89 lakkgvpvigpsgltgekcspnvfslgpttsaqaaalvdylakelggkkvaligadyafgraleaaakaalka 161 ++++g++++g++++ + sp +f+l+ +a a ++d +++e+gg+ ++ +++d+ a+++++k+a+ + FUN_001850-T2 66 VNENGIIFFGAVSS---DKSPSTFPLRDKVYAAAPYWAD-VFTERGGNIWYRLTSDNVTMYAITRDIKRAFPR 134 67889999987544...479*******************.58889***********************99865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (964 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 634 (0.0248189); expected 510.9 (0.02) Passed bias filter: 572 (0.0223919); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.39u 0.41s 00:00:00.80 Elapsed: 00:00:00.41 # Mc/sec: 9427.78 // Query: FUN_001851-T1 [L=464] Description: FUN_001851 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-47 161.5 0.8 7e-19 68.7 0.0 3.2 3 CUB CUB domain 1.7e-09 38.0 12.2 0.0042 17.3 0.2 4.5 4 CUB_2 CUB-like domain 4e-08 33.3 0.3 0.051 13.6 0.1 3.3 3 CDCP1_CUB_6 CDCP1 CUB domain 4.3e-05 23.8 0.2 0.37 11.1 0.0 2.7 2 CUB_M02D8_5_3rd M02D8_5-like, third CUB domain 0.0019 18.9 4.6 1.3 9.8 0.1 3.7 4 FN3_IL27B_N IL27B N-terminal FN3 domain ------ inclusion threshold ------ 0.062 14.3 0.0 0.57 11.2 0.0 2.4 3 Egh16-like Egh16-like virulence factor 0.41 11.6 2.8 24 6.0 0.0 3.5 3 IL12p40_C Cytokine interleukin-12p40 C-terminus Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.0 0.0 2e-15 7.4e-12 26 108 .. 46 127 .. 29 129 .. 0.85 2 ! 43.9 0.0 9.5e-15 3.5e-11 5 110 .] 144 249 .. 138 249 .. 0.86 3 ! 68.7 0.0 1.9e-22 7e-19 4 110 .] 263 370 .. 258 370 .. 0.84 Alignments for each domain: == domain 1 score: 46.0 bits; conditional E-value: 2e-15 CUB 26 eCvweirvekgksvklkfedfeleeeee..caydyvevrdgeeasskllgkfcG.sekpediksssnqllikfvsdesvskkGFka 108 +C w ++v+++++vkl+++++++++ + c +dy+++rdg ++s ll+++c + +++++ss+ q++++++s++ + ++F+a FUN_001851-T1 46 TCSWVLTVPENYTVKLTITQMNVDSGGNfnCFNDYLQIRDGANSS--LLAQICNsYPSSSVFRSSGTQMWVEYKSTQAS--NSFEA 127 7***********************766677************966..******8445567889***********98765..45555 PP == domain 2 score: 43.9 bits; conditional E-value: 9.5e-15 CUB 5 ltessgsisspnypkeYeenkeCvweirvekgksvklkfed..feleeeee...caydyvevrdgeeasskllgkfcGsekpediksssnqllikf 95 ++++sg ++sp yp++++++++C w+i+ + +++ l f+ + + +++ ca d +e+ d a+ k+c ++ ++ s +n++ +++ FUN_001851-T1 144 ANDTSGLLTSPFYPNNFPNDMDCSWNITGQAESRFVLIFRFlcLGICTSSLsqpCACDSLEIGDVFGAR-----KICPQTELIPFISVENKISLSL 234 678899*********************999999977766662266665444678**********99966.....99*9999*************** PP CUB 96 vsdesvskkGFkaty 110 v+de++s+kGF a+y FUN_001851-T1 235 VTDEQNSAKGFLAKY 249 ************998 PP == domain 3 score: 68.7 bits; conditional E-value: 1.9e-22 CUB 4 eltessgsisspnypkeYeenkeCvweirvekgksvklkfedfeleeeee.caydyvevrdgeeas.skllgkfcGsekpediksssnqllikfvs 97 +lt++sg + sp +p++Y++n+eC w+i +++g ++ l+f +f++ee c dyvev + +s +k +g++ + + ++ +++++i+f+s FUN_001851-T1 263 QLTNTSGWFPSPGFPSSYPNNVECAWTIPIPPGLKIYLTFLEFDVEECGAsCSCDYVEVAFTKAQSsQKKCGRIASGGWVLK-NAINDEIVITFKS 357 499*******************************************76546********87666553788888884444444.445899******* PP CUB 98 desvskkGFkaty 110 d + ++kGF+a y FUN_001851-T1 358 DGQGRQKGFEAVY 370 **********988 PP >> CUB_2 CUB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.2 1.2e-06 0.0042 41 108 .. 44 121 .. 24 130 .. 0.69 2 ! 9.4 0.3 0.00033 1.2 6 114 .. 138 249 .. 136 252 .. 0.69 3 ! 14.8 0.3 7.1e-06 0.026 24 60 .. 270 302 .. 258 331 .. 0.83 4 ? -3.3 0.0 2.8 1e+04 65 79 .. 424 438 .. 414 441 .. 0.70 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 1.2e-06 CUB_2 41 nqnCsyninvPkgyyakvtisaktnd.........essitvtdslgks..ekvtssdkepyffvspkftinlstgsksv 108 +Cs+ +vP++y +k+ti++ +n +++++++d ++ s +++ +s + +f s ++++ + +s ++ FUN_001851-T1 44 VLTCSWVLTVPENYTVKLTITQ-MNVdsggnfncfNDYLQIRDGANSSllAQICNSYPSSSVFRSSGTQMWVEYKSTQA 121 568****************987.33224666666778888888777776677777777777777777776666555544 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00033 CUB_2 6 CksgtvtinkpangsipvyYPetwnesaelpkipanqnCsyninvPkgyyakvtisaktnd..essitvtdslgksekvtssdkepyffvspkfti 99 C+ + + n+++ + +YP+++ +++ + ++q s + + + + + +s ++ +s+++ d g + +++ p++ v++k ++ FUN_001851-T1 138 CPRNVI-ANDTSGLLTSPFYPNNFPNDMDCSWNITGQAESRFVLIFRFLCLGICTSSLSQPcaCDSLEIGDVFGARKICPQTELIPFISVENKISL 232 755555.55555544444999996555555555555555555566666666666666555588899999999999999999999999999999999 PP CUB_2 100 nlstgsksv..sFgfkv 114 +l+t+++++ F +k+ FUN_001851-T1 233 SLVTDEQNSakGFLAKY 249 99999999855555554 PP == domain 3 score: 14.8 bits; conditional E-value: 7.1e-06 CUB_2 24 yYPetwnesaelpkipanqnCsyninvPkgyyakvti 60 ++P+ ++++p+n +C ++i +P g+ +++t+ FUN_001851-T1 270 WFPSP----GFPSSYPNNVECAWTIPIPPGLKIYLTF 302 55555....45889****************9999987 PP == domain 4 score: -3.3 bits; conditional E-value: 2.8 CUB_2 65 ndessitvtdslgks 79 d+ss tvtds+ k FUN_001851-T1 424 SDDSSATVTDSTTKR 438 348999999998775 PP >> CDCP1_CUB_6 CDCP1 CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.7 0.0 0.004 14 32 52 .. 46 66 .. 42 71 .. 0.89 2 ! 10.0 0.0 0.00019 0.7 12 50 .. 145 183 .. 139 194 .. 0.82 3 ! 13.6 0.1 1.4e-05 0.051 13 61 .. 266 314 .. 256 335 .. 0.78 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.004 CDCP1_CUB_6 32 tvsWivsvpskqkaelkflnl 52 t sW+ +vp++++ +l+++++ FUN_001851-T1 46 TCSWVLTVPENYTVKLTITQM 66 68***************9875 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00019 CDCP1_CUB_6 12 kkspvlLatPnwpeGmkpsstvsWivsvpskqkaelkfl 50 ++++ lL +P +p+ ++++ sW+++ ++ + l f+ FUN_001851-T1 145 NDTSGLLTSPFYPNNFPNDMDCSWNITGQAESRFVLIFR 183 678889********************9777777766665 PP == domain 3 score: 13.6 bits; conditional E-value: 1.4e-05 CDCP1_CUB_6 13 kspvlLatPnwpeGmkpsstvsWivsvpskqkaelkflnlsqpkCekkh 61 +++ + +P++p++ +++ W + +p+ k l+fl+ +C + FUN_001851-T1 266 NTSGWFPSPGFPSSYPNNVECAWTIPIPPGLKIYLTFLEFDVEECGASC 314 55666789*******************************9988887654 PP >> CUB_M02D8_5_3rd M02D8_5-like, third CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.1 0.00031 1.1 18 107 .. 151 247 .. 141 252 .. 0.66 2 ! 11.1 0.0 0.0001 0.37 25 108 .. 278 369 .. 270 373 .. 0.77 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00031 CUB_M02D8_5_3rd 18 gtanfGseaydnnlnCsysftrtavkn.....sllalal..eyetekC.CDvlsidGlakeeqiyqGfqasvlffasteklsllfssDgvvegt 103 t+ f + ++n ++Cs+++t +a + l l++ + ++ C CD l+i + ++i ++ + f+ +k+sl + +D ++ FUN_001851-T1 151 LTSPFYPNNFPNDMDCSWNITGQAESRfvlifRFLCLGIctSSLSQPCaCDSLEIGDVFGARKICPQ-TELIPFISVENKISLSLVTDEQNSAK 243 577889999************9977663322222333331133345566899998888776666543.33445566667788888888877777 PP CUB_M02D8_5_3rd 104 Gfna 107 Gf a FUN_001851-T1 244 GFLA 247 7765 PP == domain 2 score: 11.1 bits; conditional E-value: 0.0001 CUB_M02D8_5_3rd 25 eaydnnlnCsysftrtavknsllalaleyetekC.....CDvlsidGlakee.qiyqGfqas...vlffasteklsllfssDgvvegtGfnas 108 ++y+nn++C++++ + ++ le++ e+C CD +++ + q G +as vl a ++++ + f+sDg Gf+a+ FUN_001851-T1 278 SSYPNNVECAWTIPIPPG-LKIYLTFLEFDVEECgascsCDYVEVAFTKAQSsQKKCGRIASggwVLKNAINDEIVITFKSDGQGRQKGFEAV 369 58***********99976.5666677999999988887899999975544334788898887322344556789*********9999999986 PP >> FN3_IL27B_N IL27B N-terminal FN3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.59 2.1e+03 14 24 .. 45 55 .. 40 66 .. 0.74 2 ! 8.3 0.0 0.0011 4 9 51 .. 159 200 .. 156 208 .. 0.77 3 ! 9.8 0.1 0.00037 1.3 8 24 .. 278 294 .. 276 321 .. 0.84 4 ? -2.4 0.1 2.4 8.8e+03 15 30 .. 385 400 .. 381 431 .. 0.68 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.59 FN3_IL27B_N 14 vdCsWtlppap 24 CsW l+ FUN_001851-T1 45 LTCSWVLTVPE 55 68****98533 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0011 FN3_IL27B_N 9 sYPqavdCsWtlppapestldtsfvatyr...lgvaakeeskpclq 51 ++P+ +dCsW+ + + + +fv +r lg+ +++ s+pc + FUN_001851-T1 159 NFPNDMDCSWNITGQ----AESRFVLIFRflcLGICTSSLSQPCAC 200 69**********965....567788888854557778888888875 PP == domain 3 score: 9.8 bits; conditional E-value: 0.00037 FN3_IL27B_N 8 ssYPqavdCsWtlppap 24 ssYP+ v+C+Wt p p FUN_001851-T1 278 SSYPNNVECAWTIPIPP 294 69**********98644 PP == domain 4 score: -2.4 bits; conditional E-value: 2.4 FN3_IL27B_N 15 dCsWtlppapestldt 30 C W+ p+ ++ +t FUN_001851-T1 385 SCPWKDPAPTTEQVPT 400 6889887533334444 PP >> Egh16-like Egh16-like virulence factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00016 0.57 85 137 .. 51 103 .. 37 131 .. 0.75 2 ? -1.3 0.0 1 3.8e+03 82 156 .. 219 295 .. 209 297 .. 0.68 3 ? -1.7 0.0 1.4 5.1e+03 52 66 .. 327 344 .. 308 405 .. 0.70 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00016 Egh16-like 85 pqvsaggsltmtlhqvnaDGaGpytckidstgtgtgakalkklkvtknvpGkn 137 +v ++ ++++t+ q+n D +G ++c d+ ga++ +++ ++ p ++ FUN_001851-T1 51 LTVPENYTVKLTITQMNVDSGGNFNCFNDYLQIRDGANSSLLAQICNSYPSSS 103 5788899********************99985533333333567777777554 PP == domain 2 score: -1.3 bits; conditional E-value: 1 Egh16-like 82 gglpqvsaggsltmtlhqvnaDGaGpytckidstgtgtgakalkklkvtknvpGk.....nglsaakakdfplkvklpag 156 + +p +s + +++++l + +++ a + +k+ds + ++ +++ +n +G s ++ ++ +++ +p+g FUN_001851-T1 219 ELIPFISVENKISLSLVTDEQNSAKGFLAKYDSVFR---LEECASMTQLTNTSGWfpspgFPSSYPNNVECAWTIPIPPG 295 557888888999999999999999999999999844...45666666666776654432212235566666666666666 PP == domain 3 score: -1.7 bits; conditional E-value: 1.4 Egh16-like 52 kkkasgcGrtlggg...k 66 ++++++cGr gg k FUN_001851-T1 327 QSSQKKCGRIASGGwvlK 344 344467888876552223 PP >> IL12p40_C Cytokine interleukin-12p40 C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.0067 24 12 47 .. 42 77 .. 40 100 .. 0.79 2 ? 3.6 0.0 0.036 1.3e+02 10 61 .. 159 215 .. 156 236 .. 0.59 3 ? -0.9 0.4 0.94 3.4e+03 11 25 .. 280 294 .. 278 346 .. 0.50 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0067 IL12p40_C 12 sGeFtCsWtkeskrskkvkl.vkasrlssekrevsCs 47 sG tCsW + ++ +vkl +++ + + ++++C FUN_001851-T1 42 SGVLTCSWVLTVPENYTVKLtITQMN-VDSGGNFNCF 77 6888********99899***777766.5788888886 PP == domain 2 score: 3.6 bits; conditional E-value: 0.036 IL12p40_C 10 nYsGeFtCsWtkeskrskk.vklvkasrls....sekrevsCskveeldakkygveC 61 n+ + CsW+ + + +++ v++++ l s ++ + C++ e +d ++ C FUN_001851-T1 159 NFPNDMDCSWNITGQAESRfVLIFRFLCLGictsSLSQPCACDSLEIGDVFGARKIC 215 7777889******99888865545532222222255555555555555555555555 PP == domain 3 score: -0.9 bits; conditional E-value: 0.94 IL12p40_C 11 YsGeFtCsWtkeskr 25 Y + +C Wt FUN_001851-T1 280 YPNNVECAWTIPIPP 294 666667777665533 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (464 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 589 (0.0230573); expected 510.9 (0.02) Passed bias filter: 436 (0.0170679); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4508.77 // Query: FUN_001852-T1 [L=74] Description: FUN_001852 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.11 13.9 0.1 1.1 10.8 0.0 2.0 2 Conotoxin Conotoxin Domain annotation for each model (and alignments): >> Conotoxin Conotoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.031 8e+02 12 27 .. 8 24 .. 7 31 .. 0.71 2 ? 10.8 0.0 4.2e-05 1.1 5 41 .. 32 68 .. 29 74 .] 0.77 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.031 Conotoxin 12 Lllt.tlatadldgdqp 27 L+lt t++++d++ q+ FUN_001852-T1 8 LFLTpTACHNDGGSAQD 24 78896777777766664 PP == domain 2 score: 10.8 bits; conditional E-value: 4.2e-05 Conotoxin 5 ivlivavLllttlatadldgdqpakrkakaledrkse 41 i++iv+vLl+ + +++l+ ++ k+k+++l+ k+ FUN_001852-T1 32 IIVIVLVLLAWFTGHVCLQIAEERKEKTNKLSTIKRR 68 6789999999877888888888888888887766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (74 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1439 (0.056332); expected 510.9 (0.02) Passed bias filter: 921 (0.036054); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 754.19 // Query: FUN_001853-T1 [L=375] Description: FUN_001853 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-46 156.0 0.0 1.2e-21 77.6 0.0 2.3 2 CUB CUB domain 1.3e-10 41.7 0.1 0.00014 22.2 0.0 2.3 2 CUB_M02D8_5_3rd M02D8_5-like, third CUB domain 0.0014 18.9 0.4 1.3 9.3 0.0 2.9 2 CUB_2 CUB-like domain Domain annotation for each model (and alignments): >> CUB CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 77.6 0.0 1.4e-25 1.2e-21 5 110 .] 25 133 .. 19 133 .. 0.93 2 ! 76.4 0.0 3.3e-25 2.8e-21 4 110 .] 147 261 .. 142 261 .. 0.93 Alignments for each domain: == domain 1 score: 77.6 bits; conditional E-value: 1.4e-25 CUB 5 ltessgsiss..pnypkeYeenkeCvweirvekg.ksvklkfedfeleeeeecaydyvevrdgeeasskllgkfcGsekpediksssnqllikfvs 97 + ++sg+i s p +p Y ++ +C+w+i++++ ++v+l+f+ f++e+ ++c d+vev+d +++ lgkfcGs kp ++ s++++ll+ f+s FUN_001853-T1 25 FGNRSGTIRStlPGGPFLYANDLNCEWNITISHTaSHVQLSFSFFDVENCRKCSCDVVEVFDVVGPKKSSLGKFCGSVKPGPFYSTKQTLLVVFKS 120 56789999997789****************9876156**************************9999***************************** PP CUB 98 desvskkGFkaty 110 d+ + ++GF a+y FUN_001853-T1 121 DHGNGHRGFTASY 133 ***********99 PP == domain 2 score: 76.4 bits; conditional E-value: 3.3e-25 CUB 4 eltessgsisspnypk..eYeenkeCvweirvekgksvklkfedfeleeeee......caydyvevrdgeeasskllgkfcGsekpediksssnql 91 ++ +s gsi sp++ + +Y++n++Cvw+i+++++ ++klk+ + +++ + c d++e+rdg++++ +ll+ +cG+e d+ ss+ +l FUN_001853-T1 147 QIFDSVGSIASPDFHNrrHYPDNMDCVWNITTPPRTRIKLKLLAMSIQRCGRigtgnaCSCDFLEIRDGYRSNDHLLATLCGNELVGDLFSSGRHL 242 388999********98668****************************98766777888************************************** PP CUB 92 likfvsdesvskkGFkaty 110 +++f sde+v+++GF a + FUN_001853-T1 243 WVRFRSDENVTSSGFYAMF 261 ***************9876 PP >> CUB_M02D8_5_3rd M02D8_5-like, third CUB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.0 1.6e-08 0.00014 23 111 .. 39 135 .. 24 137 .. 0.79 2 ! 17.1 0.0 6.3e-07 0.0053 18 108 .. 156 260 .. 148 264 .. 0.75 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 1.6e-08 CUB_M02D8_5_3rd 23 GseaydnnlnCsysftrtavknsllalale.yetekC....CDvlsi.dGlakee...qiyqGfqasvlffasteklsllfssDgvvegtGfna 107 G y+n lnC++++t + + s + l++ ++ e+C CDv+++ d +++++ + G ++ f+ ++++l + f+sD + Gf a FUN_001853-T1 39 GPFLYANDLNCEWNITISHT-ASHVQLSFSfFDVENCrkcsCDVVEVfDVVGPKKsslGKFCGSVKPGPFYSTKQTLLVVFKSDHGNGHRGFTA 131 6778***********99955.55566665424666655559****98455666555567899******************************99 PP CUB_M02D8_5_3rd 108 sven 111 s e FUN_001853-T1 132 SYES 135 9876 PP == domain 2 score: 17.1 bits; conditional E-value: 6.3e-07 CUB_M02D8_5_3rd 18 gtanfGs.eaydnnlnCsysftrtavkn...sllalaley....et.ekC.CDvlsi.dGlakee...qiyqGfqasvlffasteklsllfssD 97 + ++f + y++n++C +++t +++ +lla++++ t + C CD l+i dG +++ + G + f s ++l + f sD FUN_001853-T1 156 ASPDFHNrRHYPDNMDCVWNITTPPRTRiklKLLAMSIQRcgriGTgNACsCDFLEIrDGYRSNDhllATLCGNELVGDLFSSGRHLWVRFRSD 249 5566665257***********9655544333999999985222223245669*****55777766565677899999999************** PP CUB_M02D8_5_3rd 98 gvvegtGfnas 108 v + Gf a FUN_001853-T1 250 ENVTSSGFYAM 260 *******9875 PP >> CUB_2 CUB-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.1 0.2 0.0015 13 36 108 .. 41 125 .. 37 136 .. 0.53 2 ! 9.3 0.0 0.00015 1.3 36 61 .. 164 189 .. 140 199 .. 0.86 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0015 CUB_2 36 pkipanqnCsyninvPkgyyakvtisaktnd........essitvtdslgks.....ekvtssdkepyffvspkftinlstgsksv 108 ++++ nC++ni++ +v++s ++ d + ++v+d g + ++ s++ p++ +++++ + ++++ ++ FUN_001853-T1 41 FLYANDLNCEWNITISHTA-SHVQLSFSFFDvencrkcsCDVVEVFDVVGPKksslgKFCGSVKPGPFYSTKQTLLVVFKSDHGNG 125 6789999*******96543.233332222222223334444555555444433334455556666666666666666666666666 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00015 CUB_2 36 pkipanqnCsyninvPkgyyakvtis 61 +p+n +C +ni+ P + +k+++ FUN_001853-T1 164 RHYPDNMDCVWNITTPPRTRIKLKLL 189 579*************9999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (375 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 720 (0.0281856); expected 510.9 (0.02) Passed bias filter: 291 (0.0113917); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3660.35 // Query: FUN_001854-T1 [L=135] Description: FUN_001854 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-05 26.3 21.9 2.4e-05 25.5 21.9 1.4 1 Toxin_TOLIP Snake toxin and toxin-like protein 3.5e-05 24.5 12.0 4.3e-05 24.2 12.0 1.1 1 BAMBI BMP and activin membrane-bound inhibitor (BA 0.0038 18.6 23.7 0.0055 18.1 23.7 1.3 1 Activin_recp Activin types I and II receptor domain 0.0067 17.3 24.8 0.0098 16.8 24.8 1.3 1 UPAR_LY6 u-PAR/Ly-6 domain ------ inclusion threshold ------ 0.076 13.6 0.1 0.15 12.7 0.1 1.5 1 WHD_NOD2 NOD2 winged helix domain 0.12 12.3 0.5 0.16 11.9 0.5 1.2 1 TIM-barrel_MTC6 MTC6 partial TIM-barrel domain 1.9 10.1 24.3 2.4 9.7 24.3 1.1 1 QVR Quiver family u-PAR/Ly-6-like domain Domain annotation for each model (and alignments): >> Toxin_TOLIP Snake toxin and toxin-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 21.9 6.5e-09 2.4e-05 1 72 [] 21 102 .. 21 102 .. 0.79 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 6.5e-09 Toxin_TOLIP 1 LkCytCeeek..snsnCl.ketkCsesekyCvttvtsa.kskklisksCsss......CeessselgvasvsvsCCqtdlCN 72 L+C +C+ + ++++C + ++Cs+++++C t + ++ +k+ +k C + C++ +++g +s +vsCCq+dlCN FUN_001854-T1 21 LQCNSCHFDTfnNQTECVtTNQTCSSQDTFCFTYMDERpDGTKTFTKGCGGEvcrtgyCQSIINSIGRKSCNVSCCQEDLCN 102 89****8655226789*846799***************96588999*99755433344677777777788***********9 PP >> BAMBI BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 12.0 1.2e-08 4.3e-05 3 106 .. 3 107 .. 1 108 [. 0.77 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 1.2e-08 BAMBI 3 slvsiwlqlelcamav...lltkgeircycdaahcvatgymckselnacftrvldpqntnsplthgcldsllnsadvcssksvrdrsg.ssaplec 94 s++++ + + lc++a + + + cv+t c s+ + cft + + + +t+gc + ++ c+s + +++g s ++ c FUN_001854-T1 3 SVLALVVYVSLCSLAAdclQCNSCHFDTFNNQTECVTTNQTCSSQDTFCFTYMDERPDGTKTFTKGCGGEVCRTG-YCQS--IINSIGrKSCNVSC 95 566677778888887511033445667788899*******************9999999999*****99988765.6776..45555515667*** PP BAMBI 95 chedmcnyrglh 106 c+ed+cn g + FUN_001854-T1 96 CQEDLCNKDGYQ 107 *******98865 PP >> Activin_recp Activin types I and II receptor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 23.7 1.5e-06 0.0055 5 78 .. 26 104 .. 18 105 .. 0.78 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 1.5e-06 Activin_recp 5 Cetsk......Ceedesnvtcetd.gsCfssvekettgkikvvkkgclsreqdpleCktsnkpeqlns.rieCCktdfCNkn 78 C+ + C +++ tc+ + +Cf+ + + +g ++kgc + ++ +C++ ++ ++s ++ CC++d+CNk+ FUN_001854-T1 26 CHFDTfnnqteCVTTN--QTCSSQdTFCFTYMDERPDGTK-TFTKGCGGEVCRTGYCQSIINSIGRKScNVSCCQEDLCNKD 104 4333333333488888..88888779********999999.****************998776655555***********97 PP >> UPAR_LY6 u-PAR/Ly-6 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 24.8 2.7e-06 0.0098 3 81 .. 21 103 .. 19 104 .. 0.75 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 2.7e-06 UPAR_LY6 3 lrCysClg..essssccssgs.sCpkgdtqCvtttiklsgggkksslsvkgC.spscpelnetseig...sltvtesccqsdlCns 81 l+C+sC+ +++++c +++ +C+ +dt+C+t + ++g ++ +kgC + c++ + +s i + ++sccq+dlCn+ FUN_001854-T1 21 LQCNSCHFdtFNNQTECVTTNqTCSSQDTFCFTYMDERPDG---TKTFTKGCgGEVCRTGYCQSIINsigRKSCNVSCCQEDLCNK 103 89****8511334444444446***********99999966...8889*****66666666666555444569************8 PP >> WHD_NOD2 NOD2 winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 4e-05 0.15 5 39 .. 12 46 .. 11 66 .. 0.76 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4e-05 WHD_NOD2 5 kLgkLAfeglwkqkfvFseedLkeygldesdlssg 39 +L++LA+++l++++ F+ + ++ +++ ++++s+ FUN_001854-T1 12 SLCSLAADCLQCNSCHFDTFNNQTECVTTNQTCSS 46 7****************998888888887666665 PP >> TIM-barrel_MTC6 MTC6 partial TIM-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.5 4.5e-05 0.16 205 262 .. 24 87 .. 4 95 .. 0.88 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 4.5e-05 TIM-barrel_MTC6 205 silhydtsnstlscpttveeltnlssiswrflese......FtnssireyircGysPiinnsfs 262 ++ h+dt n +++c tt++++++ +++ + +++++ Ft+ e+ r Gy i ns+ FUN_001854-T1 24 NSCHFDTFNNQTECVTTNQTCSSQDTFCFTYMDERpdgtktFTKGCGGEVCRTGYCQSIINSIG 87 5689******************9999999999777888899**************988877765 PP >> QVR Quiver family u-PAR/Ly-6-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 24.3 0.00066 2.4 2 86 .] 19 102 .. 18 102 .. 0.85 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 0.00066 QVR 2 kCYqCnseedpeCedefdekevelkeCseeatvCvkivekeeegeerviRgCeseseedeeegckeessekkkleeC...tCktdlCN 86 +C qCns + ++ ++ ++e ++ ++Cs+++t+C++++ ++ +g++++++gC e ++ +c++ ++ ++++ C +C++dlCN FUN_001854-T1 19 DCLQCNSCHFDTFNN-QTECVTTNQTCSSQDTFCFTYMDERPDGTKTFTKGC--GGEVCRTGYCQSIINSIGRKS-CnvsCCQEDLCN 102 599999996666666.778888999***************************..888889999999988887765.44449******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (135 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1201 (0.0470151); expected 510.9 (0.02) Passed bias filter: 319 (0.0124878); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.22u 0.38s 00:00:00.60 Elapsed: 00:00:00.38 # Mc/sec: 1435.66 // Query: FUN_001855-T1 [L=369] Description: FUN_001855 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0003 21.1 1.0 0.0003 21.1 1.0 2.5 2 PAN_1 PAN domain ------ inclusion threshold ------ 0.016 15.7 1.3 0.016 15.7 1.3 2.6 2 PAN_4 PAN domain 0.034 14.5 0.9 0.034 14.5 0.9 2.1 2 PAN_3 PAN-like domain Domain annotation for each model (and alignments): >> PAN_1 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 1.0 3.5e-08 0.0003 11 57 .. 36 82 .. 30 103 .. 0.81 2 ? 1.2 5.7 0.055 4.6e+02 20 38 .. 113 131 .. 96 133 .. 0.85 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 3.5e-08 PAN_1 11 legedkktvtvssaeeCaqrCaeekrCrsftYnekskkCllksessg 57 l +++ tv++ + C +C e+++C s++Yn k+++C l++ FUN_001855-T1 36 LANHAMRTVSLGDWLSCTLACHEDTSCISYNYNMKTRSCDLNDYGVL 82 5556666777778889*************************987655 PP == domain 2 score: 1.2 bits; conditional E-value: 0.055 PAN_1 20 tvssaeeCaqrCaeekrCr 38 tv+ a++C + C+ e+ Cr FUN_001855-T1 113 TVDAASQCDCSCTSESACR 131 6899**************8 PP >> PAN_4 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 1.3 1.9e-06 0.016 13 38 .. 44 69 .. 36 77 .. 0.82 2 ? 0.6 4.1 0.1 8.6e+02 15 32 .. 114 131 .. 106 133 .. 0.88 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.9e-06 PAN_4 13 llvdspeaCcaaCdedprCnawvfvk 38 ++ +++ C+ aC+ed+ C ++ ++ FUN_001855-T1 44 VSLGDWLSCTLACHEDTSCISYNYNM 69 5778999*****************97 PP == domain 2 score: 0.6 bits; conditional E-value: 0.1 PAN_4 15 vdspeaCcaaCdedprCn 32 vd +++C +C ++++C+ FUN_001855-T1 114 VDAASQCDCSCTSESACR 131 7899*************8 PP >> PAN_3 PAN-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.9 3.9e-06 0.034 17 56 .. 44 85 .. 31 89 .. 0.84 2 ? -2.3 0.8 0.66 5.6e+03 15 35 .. 110 130 .. 98 130 .. 0.82 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.9e-06 PAN_3 17 ttseswdeCvtkCledetCvlaykn..senCqlfeignvstv 56 + +w +C+ C+ed+ C+ +n + +C l ++g + +v FUN_001855-T1 44 VSLGDWLSCTLACHEDTSCISYNYNmkTRSCDLNDYGVLTSV 85 56789***************999999888**99999877665 PP == domain 2 score: -2.3 bits; conditional E-value: 0.66 PAN_3 15 eettseswdeCvtkCledetC 35 + t++ ++C C +++ C FUN_001855-T1 110 PRRTVDAASQCDCSCTSESAC 130 566788888999999999999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (369 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 724 (0.0283421); expected 510.9 (0.02) Passed bias filter: 436 (0.0170679); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3619.73 // Query: FUN_001856-T1 [L=890] Description: FUN_001856 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-115 386.1 0.6 2.6e-115 385.7 0.6 1.2 1 Glyco_hydro_31_2nd Glycosyl hydrolases family 31 TIM-barrel 2.8e-25 89.1 0.0 1.4e-24 86.8 0.0 2.2 2 Glyco_hydro_31_3rd Glycosyl hydrolase family 31 C-terminal d 1.5e-11 44.5 6.3 3.3e-11 43.4 6.3 1.6 1 Trefoil Trefoil (P-type) domain 1.5e-08 35.6 0.0 5.6e-08 33.7 0.0 1.9 2 Gal_mutarotas_2 Glycosyl hydrolase 31 N-terminal galactos Domain annotation for each model (and alignments): >> Glyco_hydro_31_2nd Glycosyl hydrolases family 31 TIM-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 385.7 0.6 4e-119 2.6e-115 1 328 [] 310 663 .. 310 663 .. 0.95 Alignments for each domain: == domain 1 score: 385.7 bits; conditional E-value: 4e-119 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 1 palppkwalGyhqsrwgykseeevkevvekfreadiPldviwlDidymdktrdftwdperFpdpkemvkelhek.glklvvivdpgiskke 90 p++pp+walG+h++rwgy s + +++v ek+r+++iP dv+w+Di+ymd++ dft+d++++ ++vk+lh+k ++++++ivdpgis+++ FUN_001856-T1 310 PYMPPYWALGFHLCRWGYGSLNGTMAVNEKMRQYGIPQDVQWNDIEYMDRHLDFTVDKNKWGGLGDFVKTLHDKyHQHYIPIVDPGISSTQ 400 78***********************************************************999*********99************9877 PP x..xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx.xxxxx.xxx RF Glyco_hydro_31_2nd 91 e..syevydegkekgvfvknkdgslyvgk.wpgssafpDftnpearewwkeelkkfllelgvdgiwiDmnEpsnfe.gsep.eekaa.kdn 175 + sy++ydeg + gvf+++++g++++g+ wpg +afpDf p ++++w + l +f + +++dg+wiDmnEpsnf gs++ + ++ dn FUN_001856-T1 401 PrgSYPAYDEGLQMGVFINSSNGETFIGQvWPGLTAFPDFSYPGTQDYWDKMLAQFRNLVEFDGLWIDMNEPSNFFdGSKQgCPASSpLDN 491 7**************************************************99999888****************9998886544430333 PP xxxxx.......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 176 degkg.......................vehydvhnlygllmakatyeglrekkpkkrpfvlsRstfaGsqryaahWsGDnastwehlres 243 + + ++hydvh+lygl++++ t+++l++ + kr++v+sRstf++++ +++hW+GDn++t+++l+ s FUN_001856-T1 492 P---PyvphvsggrlyaktvcmsakhhqYTHYDVHSLYGLMEMQRTMSALKKL-RGKRSVVISRSTFPSAGLHGGHWLGDNTATFNDLYLS 578 3...2467*****************************************9888.69*********************************** PP xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Glyco_hydro_31_2nd 244 ipgllslglsGipfvgaDiGGFa.nteseeLlvRWvqlGaFsPffrnHsskdtkrqepwafgeeveeiirkaiklRyrLlPylYtl 328 ipg+l+++++G+p+vgaDi+GF+ nt ++eL++RW+qlGaF+Pf+rnH++k++++q+p afg+++++++r+++ +Ryr++PylYtl FUN_001856-T1 579 IPGILNFNMFGVPLVGADICGFNgNT-NKELCARWTQLGAFYPFSRNHNTKGAISQDPTAFGSDFAAMARDVLLTRYRFIPYLYTL 663 ***********************555.5********************************************************97 PP >> Glyco_hydro_31_3rd Glycosyl hydrolase family 31 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 1.3 8.2e+03 22 53 .. 190 221 .. 185 232 .. 0.74 2 ! 86.8 0.0 2.3e-28 1.4e-24 1 87 [] 671 761 .. 671 761 .. 0.90 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.3 Glyco_hydro_31_3rd 22 ddqfllGdsLLvaPvleegatsvkvyLPegkW 53 +dqf+ +sLL +P l ++v+ L + +W FUN_001856-T1 190 EDQFIQISSLLPSPFLYGLGEHVNPLLLDVNW 221 799999999**999994435666655555555 PP == domain 2 score: 86.8 bits; conditional E-value: 2.3e-28 Glyco_hydro_31_3rd 1 gepvlrplflefpedeetfaiddqfllGdsLLvaPvleegatsvkvyLPegkWydyftg...ekyeg.gkevevtapldkiplfvrgGsIi 87 g+ v+rplf+efp+d++t+ id+qfllG++LL++Pvl++g++sv+ y+P+++Wyd + g ++ g g+ ++++ap dki+ ++rgG++i FUN_001856-T1 671 GSAVARPLFYEFPTDRATYGIDRQFLLGPALLITPVLTQGSSSVQGYFPNATWYDGMVGsilQAAGGgGQYHTLDAPWDKINFHIRGGHVI 761 6789****************************************************9996653333345666*****************98 PP >> Trefoil Trefoil (P-type) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.4 6.3 5.1e-15 3.3e-11 1 43 [] 25 78 .. 25 78 .. 0.89 Alignments for each domain: == domain 1 score: 43.4 bits; conditional E-value: 5.1e-15 Trefoil 1 CssvppseRvdCgy..pgiteeeCeargCCydpsv..........kpgvpwCFyp 43 Cs++p+s+R+dC y +g++e++C +rgCC++ ++ ++p+CFyp FUN_001856-T1 25 CSNIPDSNRFDC-YpeSGADEQKCLNRGCCWKVAAqdnqavdgevPLNIPYCFYP 78 ************.76999*************86666667788888999******8 PP >> Gal_mutarotas_2 Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.7 0.0 8.7e-12 5.6e-08 28 181 .. 129 267 .. 114 269 .. 0.73 2 ? -1.9 0.0 0.75 4.8e+03 108 143 .. 829 866 .. 757 869 .. 0.69 Alignments for each domain: == domain 1 score: 33.7 bits; conditional E-value: 8.7e-12 Gal_mutarotas_2 28 waveeeekeekveveveeeedelilsteklkvveikkepfrisfyrdgklvlsdndggllnfeh.lrgkewedskpkgpesvaldfslppdehv 120 +++ +++++++ev ++ +++ +t + +v +++ pf is+ ++ g + f++ +g+ +ed+ + sl p+ + FUN_001856-T1 129 FKI-YDSTSSRYEVPIQTPVVQIKAETLDYNVS-FSTFPFGISVT--------RKSTGTVIFNSgVGGMVYEDQ-------FIQISSLLPSPFL 205 444.44555555555555555555555555555.88899999955........777777777773444444444.......34566999999** PP Gal_mutarotas_2 121 yGlGEkagplnlrgt..ryrlwntDvfeygaestdplYksiPfylslrkg.rgyGvFwdntaet 181 yGlGE+ pl l r +l+ D +++ e+ +lY+ P+y+sl ++ ++ GvF++n+ + FUN_001856-T1 206 YGLGEHVNPLLLDVNwtRATLFARD--QGNPEGLLNLYGVFPYYMSLENDgNANGVFLLNSNAM 267 *********77766555********..999*****************9977*********9765 PP == domain 2 score: -1.9 bits; conditional E-value: 0.75 Gal_mutarotas_2 108 valdfslppde..hvyGlGEkagplnlrgtryrlwntD 143 v+++ slpp +v+G + + +g ++r++n + FUN_001856-T1 829 VRFHESLPPLStvQVFGVSGQPSSVTVNGSPVRNFNYN 866 55555666654457888888999999999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (890 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 397 (0.0155412); expected 510.9 (0.02) Passed bias filter: 369 (0.0144451); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 8490.82 // Query: FUN_001857-T1 [L=530] Description: FUN_001857 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-61 208.2 1.2 3.9e-61 207.8 1.2 1.2 1 Aerolysin Aerolysin toxin ------ inclusion threshold ------ 0.15 12.7 5.7 0.044 14.5 2.5 1.8 2 DERM Dermatopontin Domain annotation for each model (and alignments): >> Aerolysin Aerolysin toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 207.8 1.2 3.1e-65 3.9e-61 2 331 .. 192 524 .. 191 529 .. 0.90 Alignments for each domain: == domain 1 score: 207.8 bits; conditional E-value: 3.1e-65 Aerolysin 2 dladvktrvvdesaefykplarLAhyLGygWcggtrsqyvGEDfsvtRngDswvveadkkGscnGYraderlkmklsdfkfevkPdslklGdpvis 97 +l++vktr++d + + +la+LA++LGygW+gg+r + +GEDf R+gDsw +++++ +c GY++ rlk+ + +f f+vk ++ + + ++ FUN_001857-T1 192 SLDEVKTRIMDVT---LFNLALLANFLGYGWAGGCRGRIAGEDF--LRDGDSW--KSHYQRGCAGYMSTSRLKIVYDNFGFKVK--KMDYSEAETQ 278 899********77...889*************************..*******..*****************************..********** PP Aerolysin 98 drkplkyivgvvrNdsdteqshkvatlsydevknwsktetyklsekv..tiknkykfp.lvg.........etelsleleanqswaetngnsetvt 181 + kp + +g +N+++ + + + ++v+ + ++ ++ ++ + +y+ p ++g + ls + e+ q e ng+ ++ FUN_001857-T1 279 SIKPIVQDTGEIKNQDSNVVE-STIKRQIKTVRTVIHSSSTRFKTTIgaSLTLSYQSPgVIGevatgtfkaSFTLSGGKESAQVQKEANGDIKWEY 373 ***************997766.6666799999999666665555555115678899995556999998855556666788999999********** PP Aerolysin 182 lsasarklvpantkievrlklekakvdvpYefeavvsydveldgFlRWGGnargdhte.........nRPtvkytfgvgrnkdkastilyqylkrk 268 +++++ ++ ++n+ + +r++ +++ +vpY++ ++v++++ l+gFl WGG+ +g+ ++ +RPt++y g +++++++lk+ FUN_001857-T1 374 IKVKESQTTEPNSGTSYRITTSQTRYNVPYKAVIQVQFSARLEGFLIWGGGPNGKNPNyhekwrgsgDRPTFNYDIGS------GEKPFFKHLKQI 463 ******************************************************************************......89********** PP Aerolysin 269 iprevrfWdWnwlvdryGkdalkyavs....lvderkveatltGdFeavsgsaadiellatvslkgd 331 ++r+ +W W+ l+++ + y + l+de+ +e++l G+Fe+v+g + ++ ++ +v+++ FUN_001857-T1 464 SDRGEGPWLWHLLKQN-----IPYTETvlgtLTDESLYEFELEGKFEDVAGLQYNV-VWDDVPISIA 524 ***********99999.....333333334699***********************.*****98765 PP >> DERM Dermatopontin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 2.5 3.4e-06 0.044 3 131 .. 34 165 .. 32 183 .. 0.78 2 ? -2.7 0.1 0.65 8.3e+03 29 66 .. 367 400 .. 358 412 .. 0.40 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.4e-06 DERM 3 ldqplsftCpsgqglvsvkSehsnkke.D..Rrwsfs..CkkvgagtseatetswssevnqldqavsftcpsnsylsgveSehsnskeDRrwkfqC 93 ++++ + Cp++q+l +vk ++++ D R ++ C++ + + +++++ ++ +++++ tcp +++++g++ sn+ + +w C FUN_001857-T1 34 MQKEGYSWCPDQQSLLYVKGFQRDSQAsDdlRGFKTVkcCQPPPVHIGKPHTCTSADWELSFKREGWATCPPGHIIRGLHRGSSNQLRSIQWVTCC 129 56777889***********9887777666234465424488888899***********99**************************9999998888 PP DERM 94 arisg.aklsnCsttsylnsldeelsfevs.sgrvitGle 131 + + + + ++C+ + +l + ++e + +g++++G++ FUN_001857-T1 130 KPAFQpHRYRSCYDQ----DLGGGDKWECNrDGYYLAGIH 165 886665999999765....444445566555667777765 PP == domain 2 score: -2.7 bits; conditional E-value: 0.65 DERM 29 eDRrwsfsCkkvgagtseatetswssevnqldqavsft 66 +D +w++ k + +++ ++ ++++ ++++ ++ FUN_001857-T1 367 GDIKWEYIKVKES--QTTEP--NSGTSYRITTSQTRYN 400 4555555433222..11111..1111122223333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (530 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 880 (0.034449); expected 510.9 (0.02) Passed bias filter: 694 (0.0271677); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.36s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5107.21 // Query: FUN_001858-T1 [L=248] Description: FUN_001858 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-11 43.8 0.3 4.7e-11 43.0 0.3 1.4 1 Aerolysin Aerolysin toxin ------ inclusion threshold ------ 0.015 16.0 1.6 0.026 15.2 1.2 1.6 2 DERM Dermatopontin 0.088 13.0 0.0 0.14 12.3 0.0 1.2 1 Ubiquitin_TPR1 Telomere repeat-binding protein 1-like, ubiqu Domain annotation for each model (and alignments): >> Aerolysin Aerolysin toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.0 0.3 5.5e-15 4.7e-11 3 54 .. 199 245 .. 197 248 .] 0.94 Alignments for each domain: == domain 1 score: 43.0 bits; conditional E-value: 5.5e-15 Aerolysin 3 ladvktrvvdesaefykplarLAhyLGygWcggtrsqyvGEDfsvtRngDsw 54 ++++k+rv+d + + ++ +LA ++G++W gg+ ++y GEDf +R+gD w FUN_001858-T1 199 MDELKQRVMDAT---MFNIGQLASMMGFAWSGGCWAKYSGEDF--RRKGDTW 245 689*******88...99**************************..******* PP >> DERM Dermatopontin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 1.6 1.4e+04 49 69 .. 28 48 .. 23 66 .. 0.62 2 ? 15.2 1.2 3e-06 0.026 37 135 .. 75 175 .. 70 191 .. 0.86 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 1.6 DERM 49 etswssevnqldqavsftcps 69 ++ ++++ ++++++ + +c+ FUN_001858-T1 28 SCFMEDWGSNFRKDDETSCEG 48 555666666666666666653 PP == domain 2 score: 15.2 bits; conditional E-value: 3e-06 DERM 37 CkkvgagtseatetswssevnqldqavsftcpsnsylsgveSehsnskeDRrwkfqCarisg.aklsnCsttsylnsldeelsfevs.sgrvitGl 130 C++ ++ + t++++ +++++ld a c+++ +l+gv+ + ns +w C+ +++ + +C++++ + +++++ e + +g++itG+ FUN_001858-T1 75 CARDQTFWNIPTQCQMPDWIKSLDGAGRSACQQGFFLRGVYRSNANSLGHIEWGKCCKPSHHpYHWGDCYNEDVSGTFNKAGLSECRrDGYFITGF 170 666666677889999999***********************************9888887777999************99988888779******* PP DERM 131 eSthd 135 e+t FUN_001858-T1 171 ETTSG 175 99865 PP >> Ubiquitin_TPR1 Telomere repeat-binding protein 1-like, ubiquitin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 1.7e-05 0.14 5 37 .. 180 212 .. 178 219 .. 0.90 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 1.7e-05 Ubiquitin_TPR1 5 sikSfkvPELfieipetaTvgsLkrtVmeavta 37 sik fk ++ eip +T+ Lk+ Vm+a + FUN_001858-T1 180 SIKKFKCCRMVEEIPTLTTMDELKQRVMDATMF 212 79999************************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (248 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 537 (0.0210217); expected 510.9 (0.02) Passed bias filter: 376 (0.0147191); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2529.10 // Query: FUN_001859-T1 [L=390] Description: FUN_001859 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-28 99.7 1.1 4.1e-28 99.1 1.1 1.2 1 Aerolysin Aerolysin toxin ------ inclusion threshold ------ 0.082 13.3 1.3 0.21 12.0 1.3 1.7 1 DNA_pol3_a_NII DNA polymerase III polC-type N-terminus II Domain annotation for each model (and alignments): >> Aerolysin Aerolysin toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 99.1 1.1 3.2e-32 4.1e-28 97 329 .. 25 262 .. 14 295 .. 0.83 Alignments for each domain: == domain 1 score: 99.1 bits; conditional E-value: 3.2e-32 Aerolysin 97 sdrkplkyivgvvrNdsdteqshkvatlsydevknwsktetyklsekvtiknkykfplvg.......etelsleleanqswaetngnsetvtlsas 185 s +++k i+ +N t + + +++ + + + kt+++ + + ++y++p + +t+++ e++ +q ++t+ ++ +l + FUN_001859-T1 25 SPDRSYKKIACNKKNTAGTSEVGIDVR--SARTLKNVKTSSWDANIGIEVGVEYQPPSTTggvgfsaKTSFKYEWGGEQEDSTTD--QDWHILMIN 116 556789999999999999999988888..444444679*******************5544999*88999999999998766665..678899999 PP Aerolysin 186 arklvpantkievrlklekakvdvpYefeavvsydveldgFlRWGGnargdhte.........nRPtvkytfgvgrnkdkastilyqylkrkipre 272 ++k++p++t ++ +++kv++pY++++v +++v+l+g++ WGG+++g+ ++ +R + +ytfg ++++y++lk++i+++ FUN_001859-T1 117 EKKQLPPKTFSKWSAFKKPQKVTIPYTATIVPKFKVKLEGYMVWGGGYDGNNPNfhhkhrgsgDRKKIEYTFGN------DQKPFYEDLKEQIDEN 206 99***********************************************************************9......899************* PP Aerolysin 273 vrfWdWnwlvdryGkdalkyavs....lvderkveatltGdFeavsgsaadiellatvslk 329 +W+W+ l+++y ya l+d + +tltG+Fe+ ++ +++ + +++ FUN_001859-T1 207 KYPWQWHALLQQYP-----YAEHfinqLIDPDFYAFTLTGQFEESTEIEVKSTWFPSRPIE 262 ************54.....4433333489999***********998887776555555554 PP >> DNA_pol3_a_NII DNA polymerase III polC-type N-terminus II # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 1.3 1.6e-05 0.21 5 55 .. 295 345 .. 294 349 .. 0.95 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 1.6e-05 DNA_pol3_a_NII 5 eiveelsskspllksllkkqkpevegnkliikvpneieknalkkkkldkii 55 +i++++++ p++ + +++ + +++n + + +++++ k++l+k+ +dk + FUN_001859-T1 295 KIIDNKKETKPPISKHFNDNDRNIDENLIRLPTKKKVDKTKLRKSTADKKE 345 69*******************************************999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (390 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 937 (0.0366804); expected 510.9 (0.02) Passed bias filter: 532 (0.020826); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3913.91 // Query: FUN_001860-T1 [L=770] Description: FUN_001860 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-33 116.9 0.6 3.1e-33 115.8 0.6 1.6 1 Reprolysin_2 Metallo-peptidase family M12B Reprolysin-lik 2.1e-28 100.4 0.3 2.1e-28 100.4 0.3 2.1 2 Reprolysin_5 Metallo-peptidase family M12 2.6e-20 73.6 0.3 4.8e-20 72.8 0.3 1.5 1 Reprolysin_3 Metallo-peptidase family M12B Reprolysin-lik 5.3e-14 53.2 5.0 5.3e-14 53.2 5.0 3.5 3 ADAM10_Cys-rich ADAM10, cysteine-rich domain 2.9e-11 43.9 1.1 5.3e-11 43.0 1.1 1.4 1 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-lik 1.2e-10 42.5 28.9 1.2e-10 42.5 28.9 3.5 3 Disintegrin Disintegrin 0.00042 21.4 0.1 0.0012 19.9 0.1 1.7 1 Pep_M12B_propep Reprolysin family propeptide 0.003 18.1 0.2 0.003 18.1 0.2 2.6 2 Reprolysin Reprolysin (M12B) family zinc metalloproteas ------ inclusion threshold ------ 0.018 14.5 0.0 0.037 13.5 0.0 1.4 1 Peptidase_M66 Peptidase M66 0.58 10.8 3.3 1.3 9.6 3.3 1.6 1 UPF0370 Uncharacterised protein family (UPF0370) Domain annotation for each model (and alignments): >> Reprolysin_2 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 115.8 0.6 1.2e-36 3.1e-33 9 193 .. 250 443 .. 242 445 .. 0.80 Alignments for each domain: == domain 1 score: 115.8 bits; conditional E-value: 1.2e-36 Reprolysin_2 9 vevlnrvnqiYeeddi......eislglrneaeieattsasdsgnn..rcnssttevrrlnllsqlegekdydlahlvllgefsggvlGLAyvg.. 94 + ++ +n iY+ d++ + +++ +++++ a ts+ +++ + +s++ v++l +l+ e ++d +la++ + ++f+ggvlGLA+vg FUN_001860-T1 250 ANHVKAANAIYK-DTVfgpgnkAEGIQF-QIQRMSANTSSDAQRSDnpYRDSNIG-VEKLLELNSEEDHDDVCLAYIFTYRDFTGGVLGLAWVGea 342 5778999*****.444122211233444.58888888888887755226666666.78999999999999************************** PP Reprolysin_2 95 .....qicqkkassrk.....tntglsttanygsaveesqeidv.vaHEvGHnFGatHdndgsssasegceenaatsaesangkfiMapa....sk 175 +ic+k+ +r +ntg++t++nyg+ v + + ++ +aHE GHnFG+ Hd ++ + +g +g++iM k FUN_001860-T1 343 gnaagGICEKGTVFRDgkkknLNTGVVTFINYGKQVSQ-KVSQItFAHETGHNFGSPHDSSAE--CAPG----------GSSGNYIMFAKatsgDK 425 ***********9998799999***************75.555555**************9966..4434..........3589****944366677 PP Reprolysin_2 176 snntqFSpcsislisdvl 193 +nn +FSpcs+ ++ +v+ FUN_001860-T1 426 RNNRLFSPCSRTSMNNVM 443 **************9987 PP >> Reprolysin_5 Metallo-peptidase family M12 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 100.4 0.3 8.1e-32 2.1e-28 4 195 .] 222 432 .. 219 432 .. 0.85 2 ? -7.3 5.4 10 2.6e+04 155 178 .. 478 501 .. 474 507 .. 0.68 Alignments for each domain: == domain 1 score: 100.4 bits; conditional E-value: 8.1e-32 Reprolysin_5 4 kvallvaaDcsyvaafgg.d..aaqaniinmvntasnvyeref.........nislglanltisdstdpetase..asssgnssdlLnefqsssaw 85 ++l + aD+ +++ ++g + +a ++n v+ a n++++++ +i++++++++ ++s+d + + + +s+ +++lL+ + s++ FUN_001860-T1 222 SCTLKMRADHLFTEFMAGsNkeRAMLIMANHVKAA-NAIYKDTvfgpgnkaeGIQFQIQRMSANTSSDAQRSDNpyRDSNIGVEKLLELN---SEE 313 699*************9966555555555666666.99999999**********************999876667777888888888888...887 PP Reprolysin_5 86 rgtqsddlavltlmtncstg.vglAwlgqlcnsgsagsvsesveks.................nsvvvstatewqvfaHEiGHnfGavHDcdssta 163 ++++ + la++++ +++ +g +glAw+g++ n +ag+++e+++++ + + vs++ + ++faHE+GHnfG++HD + FUN_001860-T1 314 DHDDVC-LAYIFTYRDFTGGvLGLAWVGEAGN--AAGGICEKGTVFrdgkkknlntgvvtfinYGKQVSQKVSQITFAHETGHNFGSPHDSSA--- 403 886665.*********************9976..678888887777899999999*******977778899*******************995... PP Reprolysin_5 164 ssqcCplsastcdaggryiMnpsss....pnitafS 195 +C++ +++g+yiM +++ +n++ fS FUN_001860-T1 404 ---ECAP----GGSSGNYIMFAKATsgdkRNNRLFS 432 ...7888....69*******9998878988888887 PP == domain 2 score: -7.3 bits; conditional E-value: 10 Reprolysin_5 155 vHDcdsstassqcCplsastcdag 178 D d s+++++cC+++ s+ ++ FUN_001860-T1 478 GYDDDESCRQDHCCQGRPSSDSNN 501 557777789999*98865444443 PP >> Reprolysin_3 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.8 0.3 1.9e-23 4.8e-20 4 123 .] 249 400 .. 246 400 .. 0.86 Alignments for each domain: == domain 1 score: 72.8 bits; conditional E-value: 1.9e-23 Reprolysin_3 4 iaslveaanqvye.relg.......irlqlaaiiitssad...tpyttkdaleildeaaevistergqsgydlvhlftkrdv.sgvgGlAyv.... 83 +a++v+aan++y+ + +g i++q+++++ ++s+d ++++++d++ +++ +e++s+e ++++++l+++ft+rd+ +gv GlA+v FUN_001860-T1 249 MANHVKAANAIYKdTVFGpgnkaegIQFQIQRMSANTSSDaqrSDNPYRDSNIGVEKLLELNSEE-DHDDVCLAYIFTYRDFtGGVLGLAWVgeag 343 7899*********6666699***********7766665542146777888899*********999.7***************9*********8888 PP Reprolysin_3 84 ...gavcnsskk..............fglnsgssplgdtgadtfaHEiGHnfGanHt 123 g++c+++ + +n+g++++ +++ +tfaHE GHnfG+ H+ FUN_001860-T1 344 naaGGICEKGTVfrdgkkknlntgvvTFINYGKQVSQKVSQITFAHETGHNFGSPHD 400 88866666666677888899999999889999999999999***************8 PP >> ADAM10_Cys-rich ADAM10, cysteine-rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 8.7 0.65 1.7e+03 15 49 .. 488 520 .. 474 522 .. 0.71 2 ? -4.5 5.5 10 2.6e+04 4 44 .. 521 561 .. 519 567 .. 0.73 3 ! 53.2 5.0 2.1e-17 5.3e-14 2 56 .] 597 647 .. 596 647 .. 0.92 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.65 ADAM10_Cys-rich 15 etCastseikeskefnkkglklkpGspCnnfqGYC 49 + C + + +++s n +g kl+pG C+ +G C FUN_001860-T1 488 DHCCQGRPSSDS--NNANGCKLRPGKTCSPSKGLC 520 334444444333..36689**************99 PP == domain 2 score: -4.5 bits; conditional E-value: 10 ADAM10_Cys-rich 4 CelcCqekgkpetCastseikeskefnkkglklkpGspCnn 44 C+ C+ ++++ C++ ++ +++++ n+ + + +p p +n FUN_001860-T1 521 CSDGCTPQNTTFLCQNETDCANATYCNGVNATCPPPVPKSN 561 55567777777789999999988888888888777766555 PP == domain 3 score: 53.2 bits; conditional E-value: 2.1e-17 ADAM10_Cys-rich 2 elCelcCqekgkpetCastseikeskefnkkglklkpGspCnnfqGYCDvFkkCR 56 +C lcC+ + + C+ t +i +e+++k++++ pG+pCn+f+GYCDvF kCR FUN_001860-T1 597 RQCLLCCMGT--DGICQPTGKI--IEEMEGKNIEQFPGAPCNDFNGYCDVFLKCR 647 68******75..689*******..577899************************9 PP >> Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.0 1.1 2.1e-14 5.3e-11 60 199 .. 283 440 .. 229 447 .. 0.70 Alignments for each domain: == domain 1 score: 43.0 bits; conditional E-value: 2.1e-14 Reprolysin_4 60 tdsetddfalddl..aedlnneslaaltstrgelnaDlaallrqdrasqqevgvawvgavclsarqvnkkgsgfaass.derd........ey... 141 ++ ++d d ++ + e+l l s + + la+++ ++ g awvg+ + a kg +f ++ ++ +y FUN_001860-T1 283 ANTSSDAQRSDNPyrDSNIGVEKLLELNSEEDHDDVCLAYIFTYRDFTGGVLGLAWVGEAGNAAGGICEKGTVFRDGKkKN-LntgvvtfiNYgkq 377 33333433344440044556788888888888888888999988889**************99************997333.25899*99955666 PP Reprolysin_4 142 ......ditfAHEiGHqfGaaHdkeseseglsvaveegsgstImayastasq....eafapnaidlin 199 +itfAHE GH+fG Hd + e+ + +sg++Im +t + f+p+ + +n FUN_001860-T1 378 vsqkvsQITFAHETGHNFGSPHDSSAECAPGG-----SSGNYIMFAKATSGDkrnnRLFSPCSRTSMN 440 6666789*********************9975.....589***9543332222346779999988873 PP >> Disintegrin Disintegrin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 1.6 0.82 2.1e+03 34 52 .. 445 464 .. 421 468 .. 0.58 2 ! 42.5 28.9 4.7e-14 1.2e-10 1 74 [. 470 555 .. 470 556 .. 0.94 3 ? -5.9 15.5 10 2.6e+04 30 74 .. 569 612 .. 559 613 .. 0.81 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 0.82 Disintegrin 34 ssgeCckekCql.ksagtvC 52 +g C ++kC + ++a+ +C FUN_001860-T1 445 VKGRCTDRKCCFvAAAEAIC 464 34667776654414555555 PP == domain 2 score: 42.5 bits; conditional E-value: 4.7e-14 Disintegrin 1 eegeeCDcGseee..cekdkCcd.........aktCklkegaqC..ssgeCckekCqlksagtvCreakdeCdleeyCnGksaeCpe 74 eegeeCDcG+ ++ c++d+Cc+ a+ Ckl++g++C s+g Cc++ C+ ++++ +C++ +++C + yCnG +a+Cp+ FUN_001860-T1 470 EEGEECDCGYDDDesCRQDHCCQgrpssdsnnANGCKLRPGKTCspSKGLCCSDGCTPQNTTFLCQN-ETDCANATYCNGVNATCPP 555 89*******988778****************999**********9778*****99***********9.578**************97 PP == domain 3 score: -5.9 bits; conditional E-value: 10 Disintegrin 30 gaqCssgeCckekC.qlksagtvCreakdeCdleeyCnGksaeCpe 74 +++C sgeC + C ++ ++ +C+e++++C l C G+ C++ FUN_001860-T1 569 RQVCLSGECSGSIClKYGFSECQCKEEERQCLL--CCMGTDGICQP 612 568999***99889778899999***9999988..79999999985 PP >> Pep_M12B_propep Reprolysin family propeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.1 4.7e-07 0.0012 16 67 .. 44 92 .. 31 118 .. 0.80 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 4.7e-07 Pep_M12B_propep 16 shelsskrrrrslseeeeseeqlsYrlsaegkelhLnLeknrellapgftve 67 s +++r rrs +++ ++++++l+ e++e+ ++L++++el+ ++f+ e FUN_001860-T1 44 SLRQQHNRVRRSSPNSD---QRIELKLKTEKREFNIRLQRDTELFTHDFVAE 92 33334889999987554...8****************************998 PP >> Reprolysin Reprolysin (M12B) family zinc metalloprotease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.2 1.2e-06 0.003 123 195 .. 374 449 .. 308 453 .. 0.80 2 ? -7.2 7.7 10 2.6e+04 138 163 .. 576 600 .. 559 612 .. 0.64 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 1.2e-06 Reprolysin 123 dkk.knlealavilaheLghnlGlqhdeekkeCkCe.ekgvCimneeags...ssgvkFskcsledfekflkkqkgaC 195 ++k + ++ ++ ahe ghn+G hd++ eC ++g im +a+s + Fs cs++ ++ + kg+C FUN_001860-T1 374 YGKqVSQKVSQITFAHETGHNFGSPHDSS-AECAPGgSSGNYIMFAKATSgdkRNNRLFSPCSRTSMNNVMD-VKGRC 449 33424555566789***************.66888789999***98876511134558******99988654.44555 PP == domain 2 score: -7.2 bits; conditional E-value: 10 Reprolysin 138 eLghnlGlqhdeekkeCkCe.ekgvCi 163 e + ++ l++ + eC+C+ e ++C+ FUN_001860-T1 576 ECSGSICLKYGFS--ECQCKeEERQCL 600 4445555555555..788876555665 PP >> Peptidase_M66 Peptidase M66 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 1.4e-05 0.037 184 213 .. 375 404 .. 357 438 .. 0.75 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.4e-05 Peptidase_M66 184 GivtgdatltgifiHEqGHalGLpHylage 213 G + ++ ++ +f HE+GH++G pH + e FUN_001860-T1 375 GKQVSQKVSQITFAHETGHNFGSPHDSSAE 404 666667777889*************65554 PP >> UPF0370 Uncharacterised protein family (UPF0370) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 3.3 0.00051 1.3 2 20 .. 673 691 .. 672 701 .. 0.89 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.00051 UPF0370 2 eWladyWWvillvlvGvli 20 eW+++yWW + l+ vG++i FUN_001860-T1 673 EWIKHYWWAVALMGVGLII 691 8***************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (770 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1036 (0.0405559); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.35u 0.44s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 7369.52 // Query: FUN_001861-T1 [L=181] Description: FUN_001861 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 6.9 5.8 6.0 8 5.6 6.0 1.1 1 Presenilin Presenilin Domain annotation for each model (and alignments): >> Presenilin Presenilin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 6.0 0.00031 8 241 316 .. 39 116 .. 17 147 .. 0.38 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.00031 Presenilin 241 eaekkkeeeeeeskkeeseeeeseksassse..eeeseeteeeesaeeeseeeseeesseaessteesseekekeese 316 ++e+ ++ +++++++e+s ++++k +++ +++ ++++++ s++++ +++ ++++++ +++++++ e++++ +++ FUN_001861-T1 39 SNENISQDDTTKNHSEQSAGNFKSKDVTKQPrsTNRFATFRTQGSQNHQGNRQLRSTNRNIADQSSSHFEDSQRLATS 116 111111111111111111111111111111110111222222222222222333333333333333332222222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1166 (0.0456449); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.43s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1815.35 // Query: FUN_001862-T1 [L=321] Description: FUN_001862 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-09 36.1 0.0 1.2e-08 35.2 0.0 1.6 1 Vg_Tdu Vestigial/Tondu family 0.00027 21.5 2.4 0.00061 20.4 2.4 1.6 1 TEADIR3 Omega loop, TEAD interacting region 3 ------ inclusion threshold ------ 0.068 14.1 5.0 0.14 13.1 5.0 1.5 1 DX DX module Domain annotation for each model (and alignments): >> Vg_Tdu Vestigial/Tondu family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.2 0.0 1.4e-12 1.2e-08 2 30 .. 54 82 .. 53 83 .. 0.90 Alignments for each domain: == domain 1 score: 35.2 bits; conditional E-value: 1.4e-12 Vg_Tdu 2 yisarCVvFtyfsGDiasvVDEHFsRALr 30 + s r V+ +yf+GD+ s+VD HFsR L FUN_001862-T1 54 HYSPRGVILMYFKGDAPSEVDRHFSRTLT 82 667799********************995 PP >> TEADIR3 Omega loop, TEAD interacting region 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 2.4 7.1e-08 0.00061 1 15 [. 106 120 .. 106 120 .. 0.96 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 7.1e-08 TEADIR3 1 vPMrkRkLPaSFWkE 15 +PM +R +PaSFW++ FUN_001862-T1 106 LPMSQRDFPASFWNP 120 6*************8 PP >> DX DX module # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 5.0 1.6e-05 0.14 5 56 .. 132 182 .. 129 200 .. 0.86 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 1.6e-05 DX 5 vkCdpkekipkkfafafCdpetgkivilgelnvngeentkveek..kCssnkdC 56 v+C++ ++++++ ++C+++t +i+ ++ ++ n+ +n++ +++ +Cssn +C FUN_001862-T1 132 VSCSQGSTMETT---SYCHSNTVNILTMSDCHSNTVNNMELNHNaaNCSSNGSC 182 678888888776...9****************999999986655569****999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1034 (0.0404776); expected 510.9 (0.02) Passed bias filter: 574 (0.0224702); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3173.79 // Query: FUN_001865-T1 [L=1751] Description: FUN_001865 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-26 92.6 4.5 1.4e-12 48.1 0.1 3.7 3 TPR_12 Tetratricopeptide repeat 1.5e-13 50.7 11.1 8.6e-06 26.1 0.1 5.6 5 TPR_10 Tetratricopeptide repeat 7.2e-12 45.1 19.1 6e-05 23.2 0.1 5.6 5 TPR_1 Tetratricopeptide repeat 8.1e-12 45.6 0.1 3.4e-11 43.6 0.1 2.1 1 Death Death domain 2e-11 43.5 16.3 0.00048 20.5 0.2 5.9 5 TPR_2 Tetratricopeptide repeat 1.5e-08 35.3 0.3 0.0054 17.5 0.0 2.5 2 ZU5 ZU5 domain 8e-08 32.3 20.0 0.00051 20.5 0.3 5.7 5 TPR_8 Tetratricopeptide repeat 2.1e-07 31.0 10.1 0.077 13.6 0.1 6.0 5 TPR_7 Tetratricopeptide repeat 1.2e-05 26.2 0.2 6e-05 24.0 0.0 2.3 1 AAA ATPase family associated with various cellul 4.4e-05 23.5 0.2 0.022 14.6 0.2 3.1 2 TPR_NPHP3 Nephrocystin-3 TPR domain 0.00027 22.0 0.0 0.0011 20.0 0.0 2.1 1 AAA_16 AAA ATPase domain 0.00037 20.4 0.0 0.001 18.9 0.0 1.7 1 TPR_MalT MalT-like TPR region 0.00044 21.2 4.3 0.019 16.0 0.4 3.7 2 Sel1 Sel1 repeat 0.00048 20.7 6.2 0.0077 16.8 0.1 4.2 3 MIT MIT (microtubule interacting and transport) 0.0005 20.9 0.6 0.0023 18.8 0.1 2.4 1 TPR_16 Tetratricopeptide repeat 0.00054 20.8 0.0 0.022 15.5 0.0 2.8 2 AAA_22 AAA domain 0.0023 18.7 3.6 5.4 7.9 0.1 4.1 4 TPR_19 Tetratricopeptide repeat 0.0035 17.8 0.4 0.81 10.1 0.1 2.7 2 DUF3856 Domain of Unknown Function (DUF3856) 0.0038 18.3 5.2 11 7.6 0.0 5.3 4 TPR_14 Tetratricopeptide repeat 0.0047 17.0 0.0 0.022 14.8 0.0 2.2 2 NB-ARC NB-ARC domain 0.0061 17.6 7.0 11 7.5 0.1 5.8 5 TPR_6 Tetratricopeptide repeat ------ inclusion threshold ------ 0.02 14.1 0.7 0.13 11.5 0.0 2.1 2 Iml2-TPR_39 Iml2/Tetratricopeptide repeat protein 39 0.034 14.4 0.0 0.13 12.6 0.0 2.1 1 ATPase_2 ATPase domain predominantly from Archaea 0.044 14.6 9.3 3.3 8.6 0.2 4.5 4 ANAPC3 Anaphase-promoting complex, cyclosome, subun 0.057 13.7 0.2 0.57 10.5 0.2 2.5 1 NACHT NACHT domain 0.063 13.8 0.0 0.4 11.2 0.0 2.4 2 nSTAND6 Novel STAND NTPase 6 0.071 13.3 3.9 1.7 8.8 0.0 4.0 4 nSTAND3 Novel STAND NTPase 3 0.072 14.0 12.3 5.2 8.0 0.2 5.6 5 TPR_IF140_C IF140 C-terminal TPR domain 0.11 12.7 8.2 4.1 7.7 3.3 3.4 2 TPR_11 TPR repeat 0.13 13.0 0.0 0.51 11.1 0.0 2.0 1 Sigma54_activ_2 Sigma-54 interaction domain 0.14 12.2 5.6 0.55 10.2 0.1 2.9 2 COP9_hel_rpt COP9 signalosome complex subunit 3, N-termin 0.24 12.1 6.4 3.1 8.5 0.1 3.9 3 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth AR 0.99 9.9 3.8 35 4.9 0.0 4.1 4 Consortin_N Consortin, N-terminal domain 1.3 9.0 7.5 22 5.1 0.2 4.4 4 SHNi-TPR SHNi-TPR 1.8 8.9 5.5 8.4 6.7 0.4 3.4 3 ARM_TT21_C Tetratricopeptide repeat protein 21 C-termin Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.5 3.2e-09 2.3e-06 10 76 .. 620 686 .. 617 687 .. 0.93 2 ! 48.1 0.1 1.9e-15 1.4e-12 4 77 .] 700 773 .. 697 773 .. 0.96 3 ! 36.0 0.0 1.2e-11 8.4e-09 7 73 .. 745 810 .. 744 814 .. 0.95 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 3.2e-09 TPR_12 10 AavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrl.ylalgdyeeAlelleqaleiae 76 +++ +r+ +y Al+ l+ +l+ +e+l++ + ++ ++++++g + y+ l+dy +Ale++ +a+++ e FUN_001865-T1 620 GEIFCRARDYKRALQSLQLCLRYIEELPEV-NIQLTRCYNAMGNCyYHGLEDYNKALEFYSKAIKMTE 686 7899***********************975.79************55699**************9987 PP == domain 2 score: 48.1 bits; conditional E-value: 1.9e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + n+++ v+ g+y+eA e++++a++l e+l p++a +rnL+ +yl++ +++eA+e e+a ei++k FUN_001865-T1 700 VTKNQIGTVYEGKGNYAEAVEYYKEAIRLLEKLKISGCPDEAFFQRNLANAYLYQDNFKEAVEPAERAFEIRKK 773 57789******************************************************************986 PP == domain 3 score: 36.0 bits; conditional E-value: 1.2e-11 TPR_12 7 nnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqale 73 +nlA++++ ++++ eA e e+a e++++ lG dhp+t ++ ++ g + lg+ ++Al+ll++a e FUN_001865-T1 745 RNLANAYLYQDNFKEAVEPAERAFEIRKKQLG-DHPDTVRSIFQQGFIETCLGESKKALDLLKKAWE 810 69*************************99997.8******************************965 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.2 4.5 3.3e+03 13 34 .. 624 645 .. 620 646 .. 0.81 2 ! 8.2 0.0 0.0048 3.5 4 38 .. 656 691 .. 653 693 .. 0.85 3 ! 19.3 0.0 1.6e-06 0.0012 4 35 .. 701 732 .. 700 732 .. 0.93 4 ! 26.1 0.1 1.2e-08 8.6e-06 7 42 .] 746 780 .. 744 780 .. 0.97 5 ? -1.3 0.0 4.9 3.6e+03 13 31 .. 793 811 .. 789 816 .. 0.83 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 4.5 TPR_10 13 raqgryeeAeelleealairer 34 ++ ++y++A++ l+ +l+ e+ FUN_001865-T1 624 CRARDYKRALQSLQLCLRYIEE 645 67899*******9999987766 PP == domain 2 score: 8.2 bits; conditional E-value: 0.0048 TPR_10 4 slnnLanal.raqgryeeAeelleealairervlGp 38 ++n ++n + + +y+ A+e++ +a++++e++ G+ FUN_001865-T1 656 CYNAMGNCYyHGLEDYNKALEFYSKAIKMTEEISGS 691 677777666599********************9985 PP == domain 3 score: 19.3 bits; conditional E-value: 1.6e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 + n++++++ g+y+eA+e+++ea+++ e++ FUN_001865-T1 701 TKNQIGTVYEGKGNYAEAVEYYKEAIRLLEKL 732 6799***********************99885 PP == domain 4 score: 26.1 bits; conditional E-value: 1.2e-08 TPR_10 7 nLanalraqgryeeAeelleealairervlGpdHPd 42 nLana+ +q +++eA+e +e+a++ir++ lG dHPd FUN_001865-T1 746 NLANAYLYQDNFKEAVEPAERAFEIRKKQLG-DHPD 780 9*****************************9.9998 PP == domain 5 score: -1.3 bits; conditional E-value: 4.9 TPR_10 13 raqgryeeAeelleealai 31 + +g+ + A++ll++a ++ FUN_001865-T1 793 TCLGESKKALDLLKKAWEM 811 67888899********987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.4 1.9 1.4e+03 8 28 .. 620 640 .. 615 643 .. 0.78 2 ! 15.8 1.4 1.8e-05 0.013 3 29 .. 656 683 .. 654 684 .. 0.86 3 ! 23.2 0.1 8.2e-08 6e-05 5 30 .. 703 728 .. 699 732 .. 0.90 4 ! 14.1 0.5 6.1e-05 0.044 6 31 .. 746 771 .. 741 774 .. 0.91 5 ? -0.2 0.0 2 1.5e+03 12 27 .. 793 808 .. 784 810 .. 0.84 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.9 TPR_1 8 GnayfklgkydeAleyyekAL 28 G ++ + +y+ Al+ + +L FUN_001865-T1 620 GEIFCRARDYKRALQSLQLCL 640 777788889999999888776 PP == domain 2 score: 15.8 bits; conditional E-value: 1.8e-05 TPR_1 3 alynlGnayfk.lgkydeAleyyekALe 29 +++ +Gn+y++ l++y++Ale+y+kA++ FUN_001865-T1 656 CYNAMGNCYYHgLEDYNKALEFYSKAIK 683 788889988765***************8 PP == domain 3 score: 23.2 bits; conditional E-value: 8.2e-08 TPR_1 5 ynlGnayfklgkydeAleyyekALel 30 +++G +y +g+y eA+eyy++A++l FUN_001865-T1 703 NQIGTVYEGKGNYAEAVEYYKEAIRL 728 899*********************98 PP == domain 4 score: 14.1 bits; conditional E-value: 6.1e-05 TPR_1 6 nlGnayfklgkydeAleyyekALeln 31 nl+nay+++ +++eA+e e+A e++ FUN_001865-T1 746 NLANAYLYQDNFKEAVEPAERAFEIR 771 9********************99986 PP == domain 5 score: -0.2 bits; conditional E-value: 2 TPR_1 12 fklgkydeAleyyekA 27 lg+ ++Al+ +kA FUN_001865-T1 793 TCLGESKKALDLLKKA 808 568999********99 PP >> Death Death domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.6 0.1 4.7e-14 3.4e-11 7 78 .. 1656 1730 .. 1654 1736 .. 0.94 Alignments for each domain: == domain 1 score: 43.6 bits; conditional E-value: 4.7e-14 Death 7 lldaveplgkdWreLarkl..glseeeideiesen.rdlrsqtyelLklWearegknatvgnLleaLrklgrrda 78 ++d ++ lg dW++Lar l ++++ id+ie+++ r++++ ++++L++W++r+ + at +L+++L+++g+ ++ FUN_001865-T1 1656 VADRFKHLGTDWKTLARDLqpEIKDGVIDAIEEDEgRCPKECCRTVLRKWYQRHTSRATSKELMRCLTNMGLANV 1730 7899999************7789999*********************************************9765 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.6 0.054 39 3 30 .. 615 642 .. 613 645 .. 0.89 2 ! 12.4 0.2 0.00026 0.19 3 31 .. 656 685 .. 654 688 .. 0.81 3 ! 20.5 0.2 6.5e-07 0.00048 6 31 .. 704 729 .. 701 732 .. 0.90 4 ! 10.9 0.5 0.00079 0.58 3 30 .. 743 770 .. 741 773 .. 0.85 5 ? 1.1 0.0 1.1 8.3e+02 5 27 .. 786 808 .. 782 810 .. 0.89 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.054 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 + y G++ ++ dy++Al+ ++ +l++ FUN_001865-T1 615 YFYIEGEIFCRARDYKRALQSLQLCLRY 642 67889******************99986 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00026 TPR_2 3 alynlGlayyk.lgdyeeAleayekAleld 31 +++++G++yy+ l dy++Ale+y kA++ FUN_001865-T1 656 CYNAMGNCYYHgLEDYNKALEFYSKAIKMT 685 5777777777559**************975 PP == domain 3 score: 20.5 bits; conditional E-value: 6.5e-07 TPR_2 6 nlGlayyklgdyeeAleayekAleld 31 + G +y+ +g+y+eA+e+y++A++l FUN_001865-T1 704 QIGTVYEGKGNYAEAVEYYKEAIRLL 729 6899*******************996 PP == domain 4 score: 10.9 bits; conditional E-value: 0.00079 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 nl++ay+++ +++eA+e e+A e+ FUN_001865-T1 743 FQRNLANAYLYQDNFKEAVEPAERAFEI 770 6789***************988888776 PP == domain 5 score: 1.1 bits; conditional E-value: 1.1 TPR_2 5 ynlGlayyklgdyeeAleayekA 27 +++G + lg+ ++Al++++kA FUN_001865-T1 786 FQQGFIETCLGESKKALDLLKKA 808 788999999************98 PP >> ZU5 ZU5 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 7.4e-06 0.0054 34 91 .. 1164 1223 .. 1146 1228 .. 0.74 2 ! 15.4 0.1 3.3e-05 0.024 4 81 .. 1288 1365 .. 1285 1381 .. 0.75 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 7.4e-06 ZU5 34 ieiylavlkkesslp.kleegetllspvvecG..PsglkfskpvilevpHcaslkseewei 91 e+ l+ + +++++ + +e+e+l+s v+e++ +gl+f k v+l +pHcas + e+ FUN_001865-T1 1164 AEVVLTSEGESEKASeDGNEKEALVSDVIELSldSPGLHFDKAVTLIIPHCASDL-KGYEV 1223 44445555444444458999********98764489***************9876.44555 PP == domain 2 score: 15.4 bits; conditional E-value: 3.3e-05 ZU5 4 vvdsrGgrlvlpntg.vsllvPegaipegtrieiylavlkkesslpkleegetllspvvecGPs.glkfskpvilevpHc 81 vv+s+ lv p+ ++++P++a+p++++ e+ a+l++ s++ + ++g++l +p++ + s ++f+kpv++++p FUN_001865-T1 1288 VVTSQESELVWPEFPlAKVTFPQNAVPQEESFEVT-AKLQEVSQR-PFRQGQILPGPILRLTSSkAVNFLKPVAVQLPLS 1365 566666666666544147899***********999.777777777.7999*********997651689*********965 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 8.3 6.1e+03 16 30 .. 628 642 .. 620 645 .. 0.87 2 ! 16.1 0.6 1.8e-05 0.013 2 32 .. 655 686 .. 654 688 .. 0.90 3 ! 20.5 0.3 7e-07 0.00051 5 30 .. 703 728 .. 701 729 .. 0.94 4 ? 6.3 0.2 0.024 18 6 33 .. 746 773 .. 746 774 .. 0.93 5 ? -0.6 0.1 4 2.9e+03 9 28 .. 991 1010 .. 991 1012 .. 0.84 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 8.3 TPR_8 16 dyeeAkeyyekalel 30 dy+ A ++++ +l++ FUN_001865-T1 628 DYKRALQSLQLCLRY 642 99**********986 PP == domain 2 score: 16.1 bits; conditional E-value: 1.8e-05 TPR_8 2 eayynlGliy.lklgdyeeAkeyyekaleldp 32 + y+ +G++y + l+dy++A e+y ka+++ + FUN_001865-T1 655 RCYNAMGNCYyHGLEDYNKALEFYSKAIKMTE 686 78999**7777*****************9976 PP == domain 3 score: 20.5 bits; conditional E-value: 7e-07 TPR_8 5 ynlGliylklgdyeeAkeyyekalel 30 +++G +y+ +g+y+eA+eyy++a++l FUN_001865-T1 703 NQIGTVYEGKGNYAEAVEYYKEAIRL 728 689*********************87 PP == domain 4 score: 6.3 bits; conditional E-value: 0.024 TPR_8 6 nlGliylklgdyeeAkeyyekaleldpd 33 nl+++yl + +++eA+e e+a e++++ FUN_001865-T1 746 NLANAYLYQDNFKEAVEPAERAFEIRKK 773 79********************999875 PP == domain 5 score: -0.6 bits; conditional E-value: 4 TPR_8 9 liylklgdyeeAkeyyekal 28 ++y++lg++e e++e l FUN_001865-T1 991 QLYIELGEKERIAEFLESLL 1010 69********9888888766 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.1 0.022 16 6 30 .. 620 642 .. 620 648 .. 0.81 2 ? 5.2 0.0 0.053 38 4 32 .. 659 686 .. 657 688 .. 0.82 3 ! 13.6 0.1 0.00011 0.077 5 28 .. 705 728 .. 703 733 .. 0.85 4 ? 5.8 0.1 0.033 24 4 25 .. 746 767 .. 745 776 .. 0.81 5 ? 0.6 0.0 1.6 1.2e+03 6 26 .. 990 1010 .. 987 1013 .. 0.88 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.022 TPR_7 6 ariyrklGdydeAirlyerlLalak 30 ++i+++ +dy++A++ ++ l++ FUN_001865-T1 620 GEIFCRARDYKRALQSLQL--CLRY 642 789***************9..5554 PP == domain 2 score: 5.2 bits; conditional E-value: 0.053 TPR_7 4 aLariyrk.lGdydeAirlyerlLalakdp 32 a++++y l+dy +A+++y + a+++++ FUN_001865-T1 659 AMGNCYYHgLEDYNKALEFYSK--AIKMTE 686 899997777***********99..666554 PP == domain 3 score: 13.6 bits; conditional E-value: 0.00011 TPR_7 5 LariyrklGdydeAirlyerlLal 28 ++ +y+ +G+y eA+++y+++++l FUN_001865-T1 705 IGTVYEGKGNYAEAVEYYKEAIRL 728 7899****************7755 PP == domain 4 score: 5.8 bits; conditional E-value: 0.033 TPR_7 4 aLariyrklGdydeAirlyerl 25 +La++y + +++eA++ er+ FUN_001865-T1 746 NLANAYLYQDNFKEAVEPAERA 767 8**************9866665 PP == domain 5 score: 0.6 bits; conditional E-value: 1.6 TPR_7 6 ariyrklGdydeAirlyerlL 26 +++y lG+ ++ ++++e lL FUN_001865-T1 990 EQLYIELGEKERIAEFLESLL 1010 689***************987 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.0 8.2e-08 6e-05 3 95 .. 132 243 .. 130 265 .. 0.71 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 8.2e-08 AAA 3 lyGppGtGKTllakavakel..gaefveisgselvsk.................yvgesekklrelfeeakkka...psvifiDEiDalakkrsss 76 l+G G+GKT++ak +++++ +++ + e ++ + +s++ +++++e+a ++ p ++++D++D+++ ++ FUN_001865-T1 132 LHGSEGVGKTACAKEICAKWpgRSHIFDLR--EAKDMravylkgmnmfglavpvGYIDSSSVVEKMLEQAFIESgglPVLFLLDNADQFTLGV-GK 224 99*****************95423333332..2222223455556666678888888999**********999999899999*******8888.55 PP AAA 77 eseeservvnaLlteldgf 95 e ++ + ++ ++l el ++ FUN_001865-T1 225 EGKNLKTAFMQFLGELTRY 243 5556666666666555544 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.2 3.1e-05 0.022 98 215 .. 653 773 .. 643 774 .. 0.77 2 ! 12.4 0.0 0.00015 0.11 116 185 .. 758 826 .. 750 846 .. 0.92 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.1e-05 TPR_NPHP3 98 vadlyealGr.flkdlgllsqalpaLqraLeiRetaldP..DhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakeleala 190 + y+a+G+ + + l ++al+ +a+ + e h + ++ q+ ++y+ g+++ a ++yk+a+ + e+ s + a la FUN_001865-T1 653 LTRCYNAMGNcYYHGLEDYNKALEFYSKAIKMTEEISGSseCHYDLPVTKNQIGTVYEGKGNYAEAVEYYKEAIRLLEKLKISGCPDEAFFQRNLA 748 56678888864567788888888888888888876543311355566688999************************9876555555555566788 PP TPR_NPHP3 191 llyqkqdkhdlaeplkkravairkk 215 + y qd ++ a +ra+ irkk FUN_001865-T1 749 NAYLYQDNFKEAVEPAERAFEIRKK 773 8888899999999999*******99 PP == domain 2 score: 12.4 bits; conditional E-value: 0.00015 TPR_NPHP3 116 sqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvake 185 + a+++ +ra eiR +l DhP rs q + + g+ ++a +l k+a e+ ++ +h +v k FUN_001865-T1 758 KEAVEPAERAFEIRKKQL-GDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEMEKSLQSGNHSVVWKR 826 689**************8.5**************************************999999999875 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 1.5e-06 0.0011 3 54 .. 109 158 .. 107 172 .. 0.84 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 1.5e-06 AAA_16 3 vgReeeleaLlallervrsgrpplvlvsGeaGvGKSalvrellralera.alv 54 gR++ +++++ l+ +g+p+ v ++G GvGK+a ++e+ + +++ +++ FUN_001865-T1 109 QGRDDDIAKITGRLK---AGQPSPVNLHGSEGVGKTACAKEICAKWPGRsHIF 158 69*****99998887...899999*****************998777665555 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.0 1.4e-06 0.001 24 190 .. 639 811 .. 626 840 .. 0.75 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 1.4e-06 TPR_MalT 24 AreALallpeddllartlatlvlGea.sllqgdlesAlaalreaeala...rradslhvtllall.qqaellraqGqLhqAaetyqqalqlaqesk 114 + + ++ lpe ++ + ++G ++ ++d ++Al+ +++a++++ + h+ l + q + +++++G ++A e y++a++l ++ k FUN_001865-T1 639 CLRYIEELPEVNIQLTRCY-NAMGNCyYHGLEDYNKALEFYSKAIKMTeeiSGSSECHYDLPVTKnQIGTVYEGKGNYAEAVEYYKEAIRLLEKLK 733 5555555555554444444.456654156688*************9962113444457766555526667************************** PP TPR_MalT 115 lealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql..epaaaleayvllarvalaqGeleeAetllqraerl 190 + p +f ++ la+ ++ + + eA + ++++ ++ ++ + ++++ + Ge + A+ ll++a ++ FUN_001865-T1 734 ISGCPDEAFFQRNLANAYLYQDNFKEAVEPAERAFEIRKKQlgDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEM 811 *************************************99844566778888888888888899999999999988666 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.4 2.7e-05 0.019 3 33 .. 656 683 .. 654 685 .. 0.90 2 ? 4.5 0.0 0.11 83 18 33 .. 712 727 .. 704 728 .. 0.83 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 2.7e-05 Sel1 3 AqyrLGylylyGlgvpkDpekAlewyekAAe 33 +++ +G +y++G D++kAle+y+kA + FUN_001865-T1 656 CYNAMGNCYYHG---LEDYNKALEFYSKAIK 683 6789********...69************87 PP == domain 2 score: 4.5 bits; conditional E-value: 0.11 Sel1 18 pkDpekAlewyekAAe 33 + ++ +A+e+y+ A + FUN_001865-T1 712 KGNYAEAVEYYKEAIR 727 669***********87 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.1 0.27 2e+02 18 32 .. 669 683 .. 668 689 .. 0.90 2 ! 16.8 0.1 1.1e-05 0.0077 14 36 .. 709 731 .. 703 749 .. 0.88 3 ? 0.8 0.0 1 7.4e+02 3 18 .. 800 815 .. 799 818 .. 0.86 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.27 MIT 18 gnyeeAlelYkeale 32 ++y +Ale+Y++a++ FUN_001865-T1 669 EDYNKALEFYSKAIK 683 68**********996 PP == domain 2 score: 16.8 bits; conditional E-value: 1.1e-05 MIT 14 eDnagnyeeAlelYkealelLlq 36 ++ +gny+eA+e+Ykea++lL + FUN_001865-T1 709 YEGKGNYAEAVEYYKEAIRLLEK 731 6889****************987 PP == domain 3 score: 0.8 bits; conditional E-value: 1 MIT 3 kAlelvkkAveeDnag 18 kAl+l+kkA e++++ FUN_001865-T1 800 KALDLLKKAWEMEKSL 815 9**********99875 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.1 3.2e-06 0.0023 3 57 .. 705 767 .. 703 773 .. 0.92 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 3.2e-06 TPR_16 3 laraalaagdyddAaaaleaalrrn........PeaaaAllglGlallrqgrlaeAaaayraa 57 ++ + g+y++A++++++a+r P+ a ++++l+ a+l q ++ eA++ +++a FUN_001865-T1 705 IGTVYEGKGNYAEAVEYYKEAIRLLeklkisgcPDEAFFQRNLANAYLYQDNFKEAVEPAERA 767 57889999*************************************************777765 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 3e-05 0.022 9 108 .. 131 241 .. 124 264 .. 0.76 2 ? 1.7 0.0 0.6 4.3e+02 27 76 .. 1672 1723 .. 1661 1731 .. 0.82 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 3e-05 AAA_22 9 vltGesGtGKTtllrrlleqldeeddsvvlvelpsstspkdllrellralglelek.elskeell.aalqealkalaa.ravliiDEaqnl..... 96 l+G +G+GKT +++++ ++ + + ++l++ ++ ++++ + + +gl + +++ ++ ++l++a+ +++ ++++++D+a+ + FUN_001865-T1 131 NLHGSEGVGKTACAKEICAKW---PGRSHIFDLREAKDMRAVYLKGMNMFGLAVPVgYIDSSSVVeKMLEQAFIESGGlPVLFLLDNADQFtlgvg 223 589****************98...8888999999999999999999999998777775677777769999999999999***********955555 PP AAA_22 97 .s.....eelleeLrsll 108 + +++++L +l FUN_001865-T1 224 kEgknlkTAFMQFLGELT 241 413344444555554444 PP == domain 2 score: 1.7 bits; conditional E-value: 0.6 AAA_22 27 eqldee.ddsvv.lvelpsstspkdllrellralglelekelskeellaalq 76 + l+ e +d+v+ +e ++ pk+ +r++lr++ +++ ++ +++el++ l+ FUN_001865-T1 1672 RDLQPEiKDGVIdAIEEDEGRCPKECCRTVLRKWYQRHTSRATSKELMRCLT 1723 333333489999899999999***************99999****9998665 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.1 0.0074 5.4 4 40 .. 626 662 .. 625 662 .. 0.96 2 ? -0.6 0.0 3.4 2.5e+03 5 20 .. 669 684 .. 666 698 .. 0.82 3 ? 7.4 0.4 0.011 7.8 5 46 .. 713 762 .. 710 771 .. 0.78 4 ? -0.7 0.0 3.7 2.7e+03 8 21 .. 799 812 .. 796 814 .. 0.84 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0074 TPR_19 4 egdydeAlalLeqalaedPdnaearllLArallalgr 40 + dy++Al+ L+ l + + +e+++ L r++ a+g+ FUN_001865-T1 626 ARDYKRALQSLQLCLRYIEELPEVNIQLTRCYNAMGN 662 68********************************997 PP == domain 2 score: -0.6 bits; conditional E-value: 3.4 TPR_19 5 gdydeAlalLeqalae 20 +dy++Al+++ +a+++ FUN_001865-T1 669 EDYNKALEFYSKAIKM 684 79**********9876 PP == domain 3 score: 7.4 bits; conditional E-value: 0.011 TPR_19 5 gdydeAlalLeqalae........dPdnaearllLArallalgrldeAea 46 g+y+eA++++++a+ + Pd a + +LA+a+l +++++eA + FUN_001865-T1 713 GNYAEAVEYYKEAIRLleklkisgCPDEAFFQRNLANAYLYQDNFKEAVE 762 78888888888877664444444477788888899999999999999975 PP == domain 4 score: -0.7 bits; conditional E-value: 3.7 TPR_19 8 deAlalLeqalaed 21 ++Al lL++a++++ FUN_001865-T1 799 KKALDLLKKAWEME 812 68*********986 PP >> DUF3856 Domain of Unknown Function (DUF3856) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.047 34 63 135 .. 621 690 .. 608 696 .. 0.79 2 ! 10.1 0.1 0.0011 0.81 22 129 .. 712 811 .. 704 820 .. 0.82 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.047 DUF3856 63 ealvklgrfeealhsaekalryfnrrGelnqdeGklwiaavfsralaleglGrkeealkafkkagemiaerkG 135 e +++ + ++ al+s + +lry++ e+n + + + a +gl ++al+++ ka +m +e G FUN_001865-T1 621 EIFCRARDYKRALQSLQLCLRYIEELPEVNIQLTRCYNAMGNCY---YHGLEDYNKALEFYSKAIKMTEEISG 690 789999******************99999988888776655444...44555567788888888888887666 PP == domain 2 score: 10.1 bits; conditional E-value: 0.0011 DUF3856 22 ageyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekalryfnrrGelnqdeGklwiaavfsralaleglGrke 117 +g+y ea e ++ a+ + + + d +a+ l++a++ +f+ea++ ae+a++ + +l d + ++f++ lG+++ FUN_001865-T1 712 KGNYAEAVEYYKEAIRLLEKLKISGCPD----EAFFQRNLANAYLYQDNFKEAVEPAERAFEIR--KKQLG-DH-PDTVRSIFQQGFIETCLGESK 799 5789999999999999999998888888....577789********************997653..33443.32.235788999999999999999 PP DUF3856 118 ealkafkkagem 129 +al+ +kka em FUN_001865-T1 800 KALDLLKKAWEM 811 999999999999 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 7.1 5.2e+03 11 29 .. 665 683 .. 655 687 .. 0.82 2 ? 7.6 0.0 0.015 11 8 30 .. 706 728 .. 700 732 .. 0.87 3 ? 6.9 0.1 0.026 19 4 30 .. 744 770 .. 742 776 .. 0.88 4 ? -0.4 0.0 5.6 4.1e+03 12 29 .. 793 810 .. 785 816 .. 0.83 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 7.1 TPR_14 11 llalGdpdeAlellerala 29 + l d+ +Ale + +a++ FUN_001865-T1 665 YHGLEDYNKALEFYSKAIK 683 566899*********9987 PP == domain 2 score: 7.6 bits; conditional E-value: 0.015 TPR_14 8 arallalGdpdeAlelleralal 30 + +++ G+++eA+e++++a++l FUN_001865-T1 706 GTVYEGKGNYAEAVEYYKEAIRL 728 6789999*************986 PP == domain 3 score: 6.9 bits; conditional E-value: 0.026 TPR_14 4 wlalarallalGdpdeAlelleralal 30 ++ la+a+l +++++eA+e +era + FUN_001865-T1 744 QRNLANAYLYQDNFKEAVEPAERAFEI 770 5679*******************9875 PP == domain 4 score: -0.4 bits; conditional E-value: 5.6 TPR_14 12 lalGdpdeAlellerala 29 lG+ ++Al+ll++a + FUN_001865-T1 793 TCLGESKKALDLLKKAWE 810 5689**********9976 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 3e-05 0.022 2 50 .. 112 159 .. 111 163 .. 0.91 2 ? -3.2 0.0 9.9 7.3e+03 125 144 .. 248 266 .. 245 288 .. 0.67 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 3e-05 NB-ARC 2 eksvekviekLlekdelqivalvGmgGvGKttLakeifnklsevegrFd 50 ++++ k+ ++L +++ v l+G GvGKt akei k ++ Fd FUN_001865-T1 112 DDDIAKITGRLK-AGQPSPVNLHGSEGVGKTACAKEICAKWPGRSHIFD 159 678999*****9.99************************9998888888 PP == domain 2 score: -3.2 bits; conditional E-value: 9.9 NB-ARC 125 renkskvllTtRseevaeav 144 + +++++llT+R +v ea FUN_001865-T1 248 KTRELRILLTSRT-SVKEAS 266 567899*****96.454443 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 2.2 1.6e+03 6 27 .. 619 640 .. 616 642 .. 0.83 2 ? 5.9 0.0 0.046 33 6 28 .. 660 683 .. 659 684 .. 0.93 3 ? 7.5 0.1 0.015 11 6 28 .. 705 727 .. 704 728 .. 0.90 4 ? 0.3 0.1 2.8 2e+03 5 21 .. 746 762 .. 745 767 .. 0.88 5 ? 0.3 0.0 2.8 2e+03 9 28 .. 992 1011 .. 991 1013 .. 0.90 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 2.2 TPR_6 6 lalsylelgdkdeAkaalqrli 27 ++++ ++ d+++A++ lq ++ FUN_001865-T1 619 EGEIFCRARDYKRALQSLQLCL 640 589999999*********9766 PP == domain 2 score: 5.9 bits; conditional E-value: 0.046 TPR_6 6 lalsyle.lgdkdeAkaalqrlik 28 ++ +y+ l d+++A++++ + ik FUN_001865-T1 660 MGNCYYHgLEDYNKALEFYSKAIK 683 799****99***********9987 PP == domain 3 score: 7.5 bits; conditional E-value: 0.015 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 ++ y+ g+++eA++++++ i+ FUN_001865-T1 705 IGTVYEGKGNYAEAVEYYKEAIR 727 7999**999**********9885 PP == domain 4 score: 0.3 bits; conditional E-value: 2.8 TPR_6 5 klalsylelgdkdeAka 21 +la +yl +++++eA++ FUN_001865-T1 746 NLANAYLYQDNFKEAVE 762 589************97 PP == domain 5 score: 0.3 bits; conditional E-value: 2.8 TPR_6 9 sylelgdkdeAkaalqrlik 28 +y+elg+k++ +++l++l++ FUN_001865-T1 992 LYIELGEKERIAEFLESLLS 1011 799**************987 PP >> Iml2-TPR_39 Iml2/Tetratricopeptide repeat protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.2 0.47 3.5e+02 269 390 .. 618 745 .. 563 756 .. 0.70 2 ? 11.5 0.0 0.00017 0.13 244 313 .. 762 831 .. 750 836 .. 0.93 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.47 Iml2-TPR_39 269 feariellkgnldeAlelleeliesqselkqv..hhlcyfelalclvf..lhkykqaansallLv....keskwSkalYtYlkaacllelykeeek 356 e+ i + ++Al++l+ ++ +el +v + + ++ + ++ + l++y++a++ ++ + ++s +S + Y + +++++ e FUN_001865-T1 618 IEGEIFCRARDYKRALQSLQLCLRYIEELPEVniQLTRCYNAMGNCYYhgLEDYNKALEFYSKAIkmteEISGSSECHYD--LPVTKNQIGTVYEG 711 47777777888899999999999888888876215567788887776623578999977654433000145667777665..56667777777777 PP Iml2-TPR_39 357 keakekavellrevpklkqkiagkslplekFaar 390 k + ++ave+ +e+ l +k + p e F r FUN_001865-T1 712 KGNYAEAVEYYKEAIRLLEKLKISGCPDEAFFQR 745 7777899999999999999988899998888877 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00017 Iml2-TPR_39 244 apleeaeelLkklrkryPkgallllfeariellkgnldeAlelleeliesqselkqvhhlcyfelalclv 313 p e+a e+ kk++ +P+ + +++++ ie g+ ++Al+ll++++e +++l+ +h +++ + + ++ FUN_001865-T1 762 EPAERAFEIRKKQLGDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEMEKSLQSGNHSVVWKRIIDHI 831 57899999999*****************************************************998886 PP >> ATPase_2 ATPase domain predominantly from Archaea # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.00017 0.13 4 44 .. 111 151 .. 109 296 .. 0.85 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00017 ATPase_2 4 RekelkeleelaergtneiiviYGpegcGKtallkeiienl 44 R+ + ++ ++ g+ +++ + G eg+GKta kei + FUN_001865-T1 111 RDDDIAKITGRLKAGQPSPVNLHGSEGVGKTACAKEICAKW 151 8999********************************98876 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 2.3 0.13 94 26 81 .. 614 680 .. 591 681 .. 0.76 2 ? 8.6 0.2 0.0045 3.3 4 57 .. 721 776 .. 718 808 .. 0.85 3 ? -0.5 0.0 3 2.2e+03 36 57 .. 795 816 .. 793 818 .. 0.87 4 ? 2.2 0.0 0.44 3.2e+02 53 77 .. 1593 1617 .. 1581 1621 .. 0.85 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.13 ANAPC3 26 ayll..AqclflngqykrAyellrkaklneksl........gcryllAqcll.kLkkykeAldaLek 81 +y + ++ ++++ +ykrA++ l+ + + + l +c ++ c++ L+ y++Al+ + k FUN_001865-T1 614 LYFYieGEIFCRARDYKRALQSLQLCLRYIEELpevniqltRCYNAMGNCYYhGLEDYNKALEFYSK 680 5555569999*********999888855555555667777799999999998789999999988765 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0045 ANAPC3 4 qyknAiflaerllaaepespedayl...lAqclflngqykrAyellrka.klnekslg 57 yk+Ai l e+l + p+ a+ lA++++ + ++k+A+e ++a ++++k lg FUN_001865-T1 721 YYKEAIRLLEKLK--ISGCPDEAFFqrnLANAYLYQDNFKEAVEPAERAfEIRKKQLG 776 69***********..88889999985666*******************9888887775 PP == domain 3 score: -0.5 bits; conditional E-value: 3 ANAPC3 36 ngqykrAyellrkaklnekslg 57 +g+ k+A++ll+ka++ eksl+ FUN_001865-T1 795 LGESKKALDLLKKAWEMEKSLQ 816 58899*********99999986 PP == domain 4 score: 2.2 bits; conditional E-value: 0.44 ANAPC3 53 ekslgcryllAqcllkLkkykeAld 77 e+ ++ r+l+A + l+L++ +++l+ FUN_001865-T1 1593 EREVKKRFLMALSRLDLEHKQKCLN 1617 566788****************997 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.2 0.00078 0.57 2 27 .. 129 154 .. 128 292 .. 0.67 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00078 NACHT 2 tvilqGeaGsGKTtLlqklalawaeg 27 +v l+G G+GKT+ +++++ +w + FUN_001865-T1 129 PVNLHGSEGVGKTACAKEICAKWPGR 154 5789*******************654 PP >> nSTAND6 Novel STAND NTPase 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00055 0.4 3 43 .. 110 152 .. 108 171 .. 0.82 2 ? -1.7 0.0 5.3 3.8e+03 90 145 .. 459 513 .. 417 516 .. 0.67 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00055 nSTAND6 3 GRekllkklvakLk..ekpillvyGlrGnGKstlieelgkkaa 43 GR++ ++k++ +Lk + + + ++G G+GK++ +e+++k + FUN_001865-T1 110 GRDDDIAKITGRLKagQPSPVNLHGSEGVGKTACAKEICAKWP 152 9************833456799****************98866 PP == domain 2 score: -1.7 bits; conditional E-value: 5.3 nSTAND6 90 aaelkrrYpaarpafiwidrAhllldesgfrnselrdlLrglakalpqwrlvlElr 145 ++++ + Y +ar++f + +ll+ +gf++s+ + + +++ ++++ +El+ FUN_001865-T1 459 DEKFLESYTEARKRFCD-HFMSQLLTIAGFVDSNFVKAFNMFTSDDANYKFAIELS 513 46677888888888864.33456788888888888777777777777777777765 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.0024 1.7 22 61 .. 132 170 .. 127 178 .. 0.85 2 ? 0.6 0.1 0.76 5.5e+02 101 128 .. 247 276 .. 220 301 .. 0.65 3 ? 0.9 0.2 0.61 4.5e+02 63 98 .. 1057 1091 .. 1032 1135 .. 0.73 4 ? -1.7 0.1 4.1 3e+03 113 151 .. 1579 1618 .. 1578 1621 .. 0.80 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0024 nSTAND3 22 itGepGiGKttlaemLalklldegyevvkissieelekvl 61 + G+ G+GKt++a+ +++k+ ++ +++ +++ +++++v+ FUN_001865-T1 132 LHGSEGVGKTACAKEICAKWPGRS-HIFDLREAKDMRAVY 170 78*****************99975.888888888888776 PP == domain 2 score: 0.6 bits; conditional E-value: 0.76 nSTAND3 101 sknk..klilTtReyilnqakekseklerl 128 sk++ +++lT+R+ + + k + +l+ l FUN_001865-T1 247 SKTRelRILLTSRTSVKEASKVEDYELQPL 276 4444425*********99999885555555 PP == domain 3 score: 0.9 bits; conditional E-value: 0.61 nSTAND3 63 pnkkqvflfDDflGetslekksknedskllsfikri 98 k+ +++f+D + ++ + ++++ ++l++ i + FUN_001865-T1 1057 FAKEALIFFEDLWTVKFK-EMNTRKTKQLFRDIMDW 1091 345679*******98665.55667788888888554 PP == domain 4 score: -1.7 bits; conditional E-value: 4.1 nSTAND3 113 yilnqakek.seklerlelskvvldleelseeekakilyn 151 +i+n+ k+ s++ er ++++++ l++l+ e+k+k l + FUN_001865-T1 1579 HIYNDHKDLaSTRPEREVKKRFLMALSRLDLEHKQKCLNE 1618 79999999944455555778899999*********99875 PP >> TPR_IF140_C IF140 C-terminal TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.66 4.8e+02 54 84 .. 67 97 .. 63 118 .. 0.72 2 ? 1.3 0.0 0.8 5.8e+02 19 40 .. 627 648 .. 625 656 .. 0.87 3 ? 8.0 0.2 0.0071 5.2 3 43 .. 653 693 .. 651 710 .. 0.80 4 ? 3.3 0.2 0.2 1.4e+02 20 41 .. 714 735 .. 706 774 .. 0.82 5 ? 3.0 0.0 0.24 1.7e+02 23 88 .. 793 859 .. 791 865 .. 0.75 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.66 TPR_IF140_C 54 kekielikkfveakklyeedpeealkqceeL 84 k k++li++fv+ k++ ee+ ++ ++ ++ FUN_001865-T1 67 KAKLTLIREFVASKSINEEEIKKIIDNYTQV 97 67999****************9998766554 PP == domain 2 score: 1.3 bits; conditional E-value: 0.8 TPR_IF140_C 19 qdYekAlgalkealkclskake 40 +dY++Al+ l+ +l+++++ e FUN_001865-T1 627 RDYKRALQSLQLCLRYIEELPE 648 9***************998765 PP == domain 3 score: 8.0 bits; conditional E-value: 0.0071 TPR_IF140_C 3 LasFYeacAqveideyqdYekAlgalkealkclskakekse 43 L + Y+a+ + dY+kAl+ +++a+k+ ++++ +se FUN_001865-T1 653 LTRCYNAMGNCYYHGLEDYNKALEFYSKAIKMTEEISGSSE 693 66778888888889999****************99987654 PP == domain 4 score: 3.3 bits; conditional E-value: 0.2 TPR_IF140_C 20 dYekAlgalkealkclskakek 41 +Y +A++ +kea++ l+k k + FUN_001865-T1 714 NYAEAVEYYKEAIRLLEKLKIS 735 9*****************9865 PP == domain 5 score: 3.0 bits; conditional E-value: 0.24 TPR_IF140_C 23 kAlgalkealkclskakeksekekekk.leelkekielikkfveakklyeedpeealkqceeLleep 88 +lg k+al l+ka e +++ ++ + k+ i++i f e + ++ +eeal+ c+++ +e+ FUN_001865-T1 793 TCLGESKKALDLLKKAWEMEKSLQSGNhSVVWKRIIDHIIYFTEGDNEKKKFEEEALAFCQRFWKEE 859 5667777888888888765555555440445688899**********9999**********999875 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.1 0.024 18 7 23 .. 668 684 .. 664 687 .. 0.84 2 ? 7.7 3.3 0.0056 4.1 7 23 .. 712 728 .. 706 755 .. 0.83 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.024 TPR_11 7 qGkyeeAieaYkkAlkl 23 + +y++A+e Y+kA+k FUN_001865-T1 668 LEDYNKALEFYSKAIKM 684 679************96 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0056 TPR_11 7 qGkyeeAieaYkkAlkl 23 +G+y eA+e Yk+A++l FUN_001865-T1 712 KGNYAEAVEYYKEAIRL 728 8**************98 PP >> Sigma54_activ_2 Sigma-54 interaction domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.0007 0.51 6 61 .. 114 167 .. 110 201 .. 0.82 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.0007 Sigma54_activ_2 6 liselkkrlekiaqsklpvfliGekGsGkelvaryLhknstpwveitdveklakap 61 i+++ rl+ a++ +pv l G +G Gk+ +a+ ++ + ++i+d+ + ++ FUN_001865-T1 114 DIAKITGRLK--AGQPSPVNLHGSEGVGKTACAKEICAKWPGRSHIFDLREAKDMR 167 5777777777..5899*******************999887779999988777776 PP >> COP9_hel_rpt COP9 signalosome complex subunit 3, N-terminal helical repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.1 0.00075 0.55 133 192 .. 578 640 .. 529 646 .. 0.75 2 ? 3.8 0.3 0.069 51 167 195 .. 657 685 .. 643 689 .. 0.83 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00075 COP9_hel_rpt 133 LlakclkpalelLdvditkisk..ekgkvdakyfL.lYyYYGGmiytalknyerAlyffevav 192 L + k a e+L+ + ++++k +k+ ++ k lY+Y G i+ ++y+rAl+ +++++ FUN_001865-T1 578 LDLNGPKEAFEVLQGEAHSLEKlqDKTVTNFKLTQgLYFYIEGEIFCRARDYKRALQSLQLCL 640 5555667788888888888887323333344433248***********************997 PP == domain 2 score: 3.8 bits; conditional E-value: 0.069 COP9_hel_rpt 167 YyYYGGmiytalknyerAlyffevavttp 195 Y G y +l +y++Al+f+ a+ + FUN_001865-T1 657 YNAMGNCYYHGLEDYNKALEFYSKAIKMT 685 55578889****************99875 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.1 5.1 3.7e+03 40 84 .. 57 105 .. 40 127 .. 0.62 2 ? 4.4 0.1 0.077 56 14 30 .. 670 686 .. 658 698 .. 0.84 3 ? 8.5 0.1 0.0043 3.1 4 106 .. 704 815 .. 702 823 .. 0.68 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 5.1 ARM_TT21_4th 40 eLllkLkqydkaekvlkqaleeek...skdleslmeev.klllLlakvr 84 +L++k + ka+ +l ++ +k ++++++++++ ++ +L + + FUN_001865-T1 57 NLFFKFGYVSKAKLTLIREFVASKsinEEEIKKIIDNYtQVNTLQIESE 105 6899999999999888877766541224566666554313444444443 PP == domain 2 score: 4.4 bits; conditional E-value: 0.077 ARM_TT21_4th 14 qYkkAinYYeaalksse 30 +Y+kA ++Y +a+k++e FUN_001865-T1 670 DYNKALEFYSKAIKMTE 686 7************9876 PP == domain 3 score: 8.5 bits; conditional E-value: 0.0043 ARM_TT21_4th 4 kiGqalvktHqYkkAinYYeaalk......sse...qksLrldLAeLllkLkqydkaekvlkqaleeekskdleslmeevklllLlakvrk.sgkk 89 +iG+ + +Y+ A++YY++a++ +s+ +++++ +LA+ +l ++++a + ++a e +k k+l ++v+ + +++ g++ FUN_001865-T1 704 QIGTVYEGKGNYAEAVEYYKEAIRlleklkISGcpdEAFFQRNLANAYLYQDNFKEAVEPAERAFEIRK-KQLGDHPDTVRSIFQQGFIETcLGES 798 57777777779***********87333332222222567888888888888888888888888887665.45555566666666666666435777 PP ARM_TT21_4th 90 eealetLkkakelqarv 106 ++al+ Lkka e+++ + FUN_001865-T1 799 KKALDLLKKAWEMEKSL 815 77888888888877665 PP >> Consortin_N Consortin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.048 35 14 35 .. 621 642 .. 620 646 .. 0.84 2 ? 1.1 0.1 0.73 5.3e+02 16 28 .. 665 677 .. 652 680 .. 0.79 3 ? 0.5 0.0 1.1 8.2e+02 5 28 .. 698 721 .. 695 728 .. 0.87 4 ? -0.7 0.1 2.7 2e+03 11 27 .. 746 762 .. 744 764 .. 0.90 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.048 Consortin_N 14 eayfleedYekAiqFiqlEklY 35 e++ + +dY++A+q +ql Y FUN_001865-T1 621 EIFCRARDYKRALQSLQLCLRY 642 899**************96666 PP == domain 2 score: 1.1 bits; conditional E-value: 0.73 Consortin_N 16 yfleedYekAiqF 28 y+ edY+kA++F FUN_001865-T1 665 YHGLEDYNKALEF 677 4667*******99 PP == domain 3 score: 0.5 bits; conditional E-value: 1.1 Consortin_N 5 LPqcLHqiaeayfleedYekAiqF 28 LP qi +y + +Y A+++ FUN_001865-T1 698 LPVTKNQIGTVYEGKGNYAEAVEY 721 7777789**************985 PP == domain 4 score: -0.7 bits; conditional E-value: 2.7 Consortin_N 11 qiaeayfleedYekAiq 27 ++a+ay +++++ A++ FUN_001865-T1 746 NLANAYLYQDNFKEAVE 762 78*************95 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.2 3.7 2.7e+03 9 18 .. 511 520 .. 511 523 .. 0.92 2 ? -1.5 0.0 3.5 2.5e+03 21 31 .. 668 678 .. 668 681 .. 0.83 3 ? 4.7 0.0 0.042 31 15 35 .. 713 733 .. 712 734 .. 0.93 4 ? 5.1 0.2 0.031 22 12 33 .. 752 773 .. 747 775 .. 0.88 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 3.7 SHNi-TPR 9 EiSLEnenFe 18 E+S+E e+F+ FUN_001865-T1 511 ELSMEPEFFS 520 89*******6 PP == domain 2 score: -1.5 bits; conditional E-value: 3.5 SHNi-TPR 21 vkDlrkaLeLr 31 ++D+ kaLe + FUN_001865-T1 668 LEDYNKALEFY 678 58******966 PP == domain 3 score: 4.7 bits; conditional E-value: 0.042 SHNi-TPR 15 enFeqAvkDlrkaLeLreell 35 n+ +Av+ +++a+ L+e+l+ FUN_001865-T1 713 GNYAEAVEYYKEAIRLLEKLK 733 69*****************97 PP == domain 4 score: 5.1 bits; conditional E-value: 0.031 SHNi-TPR 12 LEnenFeqAvkDlrkaLeLree 33 L ++nF++Av+ ++a e+r + FUN_001865-T1 752 LYQDNFKEAVEPAERAFEIRKK 773 5689***************986 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.3 0.36 2.6e+02 123 161 .. 648 687 .. 619 698 .. 0.81 2 ? 6.7 0.4 0.012 8.4 133 161 .. 703 731 .. 693 764 .. 0.87 3 ? 0.2 0.0 1.1 8e+02 108 161 .. 761 814 .. 732 821 .. 0.77 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.36 ARM_TT21_C 123 kynkscakAyellGlia.ekeqsykdAaenYekAWklske 161 + n ++ y+ +G ++ + y++A e Y kA k+++e FUN_001865-T1 648 EVNIQLTRCYNAMGNCYyHGLEDYNKALEFYSKAIKMTEE 687 56888999******997256799************99876 PP == domain 2 score: 6.7 bits; conditional E-value: 0.012 ARM_TT21_C 133 ellGliaekeqsykdAaenYekAWklske 161 + +G+++e + +y +A+e+Y++A +l ++ FUN_001865-T1 703 NQIGTVYEGKGNYAEAVEYYKEAIRLLEK 731 679********************998765 PP == domain 3 score: 0.2 bits; conditional E-value: 1.1 ARM_TT21_C 108 sgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklske 161 + ++ A e+ kk l + ++ G+i + k+A + +kAW+++k+ FUN_001865-T1 761 VEPAERAFEIRKKQLGDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEMEKS 814 455677777778888888888888888899999999999999999999998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1751 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1188 (0.0465062); expected 510.9 (0.02) Passed bias filter: 718 (0.0281073); expected 510.9 (0.02) Passed Vit filter: 95 (0.00371893); expected 25.5 (0.001) Passed Fwd filter: 35 (0.00137013); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 35 [number of targets reported over threshold] # CPU time: 0.61u 0.38s 00:00:00.99 Elapsed: 00:00:00.43 # Mc/sec: 16423.27 // Query: FUN_001865-T2 [L=1562] Description: FUN_001865 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-27 93.5 4.5 1.2e-12 48.3 0.1 3.7 3 TPR_12 Tetratricopeptide repeat 7.2e-14 51.7 10.9 7.6e-06 26.2 0.1 5.7 6 TPR_10 Tetratricopeptide repeat 4.2e-12 45.8 19.1 5.3e-05 23.4 0.1 5.6 5 TPR_1 Tetratricopeptide repeat 1.2e-11 44.3 16.3 0.00042 20.7 0.2 5.8 5 TPR_2 Tetratricopeptide repeat 1.2e-08 35.6 0.3 0.0047 17.6 0.0 2.4 2 ZU5 ZU5 domain 3.7e-08 33.4 19.7 0.00045 20.7 0.3 5.8 5 TPR_8 Tetratricopeptide repeat 1.1e-07 31.8 10.1 0.068 13.8 0.1 6.0 5 TPR_7 Tetratricopeptide repeat 9.6e-06 26.6 0.2 5.2e-05 24.2 0.0 2.4 1 AAA ATPase family associated with various cellul 3.6e-05 23.8 0.2 0.02 14.8 0.2 3.0 3 TPR_NPHP3 Nephrocystin-3 TPR domain 0.00024 22.1 0.0 0.00096 20.2 0.0 2.1 1 AAA_16 AAA ATPase domain 0.00031 21.6 0.3 0.002 19.0 0.1 2.4 1 TPR_16 Tetratricopeptide repeat 0.00032 20.5 0.0 0.00087 19.1 0.0 1.7 1 TPR_MalT MalT-like TPR region 0.00045 20.8 6.5 0.0068 17.0 0.1 4.2 3 MIT MIT (microtubule interacting and transport) 0.0017 19.1 3.8 4.8 8.1 0.1 4.2 4 TPR_19 Tetratricopeptide repeat 0.0027 18.2 0.4 0.7 10.3 0.1 2.7 2 DUF3856 Domain of Unknown Function (DUF3856) 0.0027 18.7 5.3 9.3 7.8 0.0 5.3 4 TPR_14 Tetratricopeptide repeat 0.0041 17.2 0.0 0.019 15.0 0.0 2.2 2 NB-ARC NB-ARC domain 0.0055 17.5 0.0 0.019 15.7 0.0 2.0 1 AAA_22 AAA domain 0.0061 17.6 8.3 0.017 16.2 0.4 3.7 2 Sel1 Sel1 repeat 0.007 17.4 8.1 9.3 7.6 0.1 5.9 5 TPR_6 Tetratricopeptide repeat ------ inclusion threshold ------ 0.014 15.6 1.0 1.5 8.9 0.0 3.5 3 nSTAND3 Novel STAND NTPase 3 0.016 14.4 0.8 0.11 11.7 0.0 2.2 2 Iml2-TPR_39 Iml2/Tetratricopeptide repeat protein 39 0.028 14.7 0.0 0.11 12.8 0.0 2.1 1 ATPase_2 ATPase domain predominantly from Archaea 0.046 14.6 12.3 4.6 8.2 0.2 5.6 5 TPR_IF140_C IF140 C-terminal TPR domain 0.049 13.9 0.2 0.48 10.7 0.2 2.4 1 NACHT NACHT domain 0.051 14.1 0.0 0.35 11.4 0.0 2.4 2 nSTAND6 Novel STAND NTPase 6 0.091 13.0 8.4 3.9 7.7 3.4 3.5 3 TPR_11 TPR repeat 0.092 12.7 5.5 0.48 10.4 0.1 2.9 2 COP9_hel_rpt COP9 signalosome complex subunit 3, N-termin 0.11 13.3 0.0 0.45 11.3 0.0 2.0 1 Sigma54_activ_2 Sigma-54 interaction domain 0.13 13.1 7.3 2.8 8.8 0.2 3.7 3 ANAPC3 Anaphase-promoting complex, cyclosome, subun 0.18 12.5 6.3 2.7 8.7 0.1 3.8 3 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth AR 0.66 10.5 3.8 31 5.1 0.0 4.1 4 Consortin_N Consortin, N-terminal domain 1.9 8.8 6.1 7.4 6.9 0.5 3.4 3 ARM_TT21_C Tetratricopeptide repeat protein 21 C-termin 4.9 7.2 10.0 20 5.3 0.2 4.5 4 SHNi-TPR SHNi-TPR Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.5 2.7e-09 2e-06 10 76 .. 620 686 .. 617 687 .. 0.93 2 ! 48.3 0.1 1.6e-15 1.2e-12 4 77 .] 700 773 .. 697 773 .. 0.96 3 ! 36.2 0.0 9.8e-12 7.4e-09 7 73 .. 745 810 .. 744 814 .. 0.95 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 2.7e-09 TPR_12 10 AavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrl.ylalgdyeeAlelleqaleiae 76 +++ +r+ +y Al+ l+ +l+ +e+l++ + ++ ++++++g + y+ l+dy +Ale++ +a+++ e FUN_001865-T2 620 GEIFCRARDYKRALQSLQLCLRYIEELPEV-NIQLTRCYNAMGNCyYHGLEDYNKALEFYSKAIKMTE 686 7899***********************975.79************55699**************9987 PP == domain 2 score: 48.3 bits; conditional E-value: 1.6e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 + n+++ v+ g+y+eA e++++a++l e+l p++a +rnL+ +yl++ +++eA+e e+a ei++k FUN_001865-T2 700 VTKNQIGTVYEGKGNYAEAVEYYKEAIRLLEKLKISGCPDEAFFQRNLANAYLYQDNFKEAVEPAERAFEIRKK 773 57789******************************************************************986 PP == domain 3 score: 36.2 bits; conditional E-value: 9.8e-12 TPR_12 7 nnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqale 73 +nlA++++ ++++ eA e e+a e++++ lG dhp+t ++ ++ g + lg+ ++Al+ll++a e FUN_001865-T2 745 RNLANAYLYQDNFKEAVEPAERAFEIRKKQLG-DHPDTVRSIFQQGFIETCLGESKKALDLLKKAWE 810 69*************************99997.8******************************965 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.2 3.9 2.9e+03 13 34 .. 624 645 .. 620 646 .. 0.81 2 ! 8.4 0.0 0.0041 3.1 4 38 .. 656 691 .. 653 693 .. 0.85 3 ! 19.5 0.0 1.4e-06 0.001 4 35 .. 701 732 .. 700 732 .. 0.93 4 ! 26.2 0.1 1e-08 7.6e-06 7 42 .] 746 780 .. 744 780 .. 0.97 5 ? -1.2 0.0 4.2 3.2e+03 13 31 .. 793 811 .. 789 816 .. 0.83 6 ? -2.0 0.1 8.1 6.1e+03 20 34 .. 840 854 .. 838 854 .. 0.81 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 3.9 TPR_10 13 raqgryeeAeelleealairer 34 ++ ++y++A++ l+ +l+ e+ FUN_001865-T2 624 CRARDYKRALQSLQLCLRYIEE 645 67899*******9999987766 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0041 TPR_10 4 slnnLanal.raqgryeeAeelleealairervlGp 38 ++n ++n + + +y+ A+e++ +a++++e++ G+ FUN_001865-T2 656 CYNAMGNCYyHGLEDYNKALEFYSKAIKMTEEISGS 691 677777666599********************9985 PP == domain 3 score: 19.5 bits; conditional E-value: 1.4e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 + n++++++ g+y+eA+e+++ea+++ e++ FUN_001865-T2 701 TKNQIGTVYEGKGNYAEAVEYYKEAIRLLEKL 732 6799***********************99885 PP == domain 4 score: 26.2 bits; conditional E-value: 1e-08 TPR_10 7 nLanalraqgryeeAeelleealairervlGpdHPd 42 nLana+ +q +++eA+e +e+a++ir++ lG dHPd FUN_001865-T2 746 NLANAYLYQDNFKEAVEPAERAFEIRKKQLG-DHPD 780 9*****************************9.9998 PP == domain 5 score: -1.2 bits; conditional E-value: 4.2 TPR_10 13 raqgryeeAeelleealai 31 + +g+ + A++ll++a ++ FUN_001865-T2 793 TCLGESKKALDLLKKAWEM 811 67888899********987 PP == domain 6 score: -2.0 bits; conditional E-value: 8.1 TPR_10 20 eAeelleealairer 34 e ++ eeala ++r FUN_001865-T2 840 EKKKFEEEALAFCQR 854 66788999*999987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.4 1.6 1.2e+03 8 28 .. 620 640 .. 615 643 .. 0.78 2 ! 16.0 1.4 1.5e-05 0.011 3 29 .. 656 683 .. 654 684 .. 0.86 3 ! 23.4 0.1 7e-08 5.3e-05 5 30 .. 703 728 .. 699 732 .. 0.90 4 ! 14.3 0.5 5.2e-05 0.039 6 31 .. 746 771 .. 741 774 .. 0.91 5 ? -0.0 0.0 1.7 1.3e+03 12 27 .. 793 808 .. 784 810 .. 0.84 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 1.6 TPR_1 8 GnayfklgkydeAleyyekAL 28 G ++ + +y+ Al+ + +L FUN_001865-T2 620 GEIFCRARDYKRALQSLQLCL 640 777788889999999888776 PP == domain 2 score: 16.0 bits; conditional E-value: 1.5e-05 TPR_1 3 alynlGnayfk.lgkydeAleyyekALe 29 +++ +Gn+y++ l++y++Ale+y+kA++ FUN_001865-T2 656 CYNAMGNCYYHgLEDYNKALEFYSKAIK 683 788889988765***************8 PP == domain 3 score: 23.4 bits; conditional E-value: 7e-08 TPR_1 5 ynlGnayfklgkydeAleyyekALel 30 +++G +y +g+y eA+eyy++A++l FUN_001865-T2 703 NQIGTVYEGKGNYAEAVEYYKEAIRL 728 899*********************98 PP == domain 4 score: 14.3 bits; conditional E-value: 5.2e-05 TPR_1 6 nlGnayfklgkydeAleyyekALeln 31 nl+nay+++ +++eA+e e+A e++ FUN_001865-T2 746 NLANAYLYQDNFKEAVEPAERAFEIR 771 9********************99986 PP == domain 5 score: -0.0 bits; conditional E-value: 1.7 TPR_1 12 fklgkydeAleyyekA 27 lg+ ++Al+ +kA FUN_001865-T2 793 TCLGESKKALDLLKKA 808 568999********99 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.6 0.046 35 3 30 .. 615 642 .. 613 645 .. 0.89 2 ! 12.6 0.2 0.00022 0.17 3 31 .. 656 685 .. 654 688 .. 0.81 3 ! 20.7 0.2 5.6e-07 0.00042 6 31 .. 704 729 .. 701 732 .. 0.90 4 ! 11.1 0.5 0.00067 0.51 3 30 .. 743 770 .. 741 773 .. 0.85 5 ? 1.2 0.0 0.97 7.3e+02 5 27 .. 786 808 .. 782 810 .. 0.89 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.046 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 + y G++ ++ dy++Al+ ++ +l++ FUN_001865-T2 615 YFYIEGEIFCRARDYKRALQSLQLCLRY 642 67889******************99986 PP == domain 2 score: 12.6 bits; conditional E-value: 0.00022 TPR_2 3 alynlGlayyk.lgdyeeAleayekAleld 31 +++++G++yy+ l dy++Ale+y kA++ FUN_001865-T2 656 CYNAMGNCYYHgLEDYNKALEFYSKAIKMT 685 5777777777559**************975 PP == domain 3 score: 20.7 bits; conditional E-value: 5.6e-07 TPR_2 6 nlGlayyklgdyeeAleayekAleld 31 + G +y+ +g+y+eA+e+y++A++l FUN_001865-T2 704 QIGTVYEGKGNYAEAVEYYKEAIRLL 729 6899*******************996 PP == domain 4 score: 11.1 bits; conditional E-value: 0.00067 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 nl++ay+++ +++eA+e e+A e+ FUN_001865-T2 743 FQRNLANAYLYQDNFKEAVEPAERAFEI 770 6789***************988888776 PP == domain 5 score: 1.2 bits; conditional E-value: 0.97 TPR_2 5 ynlGlayyklgdyeeAleayekA 27 +++G + lg+ ++Al++++kA FUN_001865-T2 786 FQQGFIETCLGESKKALDLLKKA 808 788999999************98 PP >> ZU5 ZU5 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 6.3e-06 0.0047 34 91 .. 1164 1223 .. 1146 1228 .. 0.74 2 ! 15.6 0.1 2.8e-05 0.021 4 81 .. 1288 1365 .. 1285 1381 .. 0.75 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 6.3e-06 ZU5 34 ieiylavlkkesslp.kleegetllspvvecG..PsglkfskpvilevpHcaslkseewei 91 e+ l+ + +++++ + +e+e+l+s v+e++ +gl+f k v+l +pHcas + e+ FUN_001865-T2 1164 AEVVLTSEGESEKASeDGNEKEALVSDVIELSldSPGLHFDKAVTLIIPHCASDL-KGYEV 1223 44445555444444458999********98764489***************9876.44555 PP == domain 2 score: 15.6 bits; conditional E-value: 2.8e-05 ZU5 4 vvdsrGgrlvlpntg.vsllvPegaipegtrieiylavlkkesslpkleegetllspvvecGPs.glkfskpvilevpHc 81 vv+s+ lv p+ ++++P++a+p++++ e+ a+l++ s++ + ++g++l +p++ + s ++f+kpv++++p FUN_001865-T2 1288 VVTSQESELVWPEFPlAKVTFPQNAVPQEESFEVT-AKLQEVSQR-PFRQGQILPGPILRLTSSkAVNFLKPVAVQLPLS 1365 566666666666544147899***********999.777777777.7999*********997651689*********965 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 7.1 5.3e+03 16 30 .. 628 642 .. 620 645 .. 0.87 2 ! 16.2 0.6 1.6e-05 0.012 2 32 .. 655 686 .. 654 688 .. 0.90 3 ! 20.7 0.3 6e-07 0.00045 5 30 .. 703 728 .. 701 729 .. 0.94 4 ? 6.5 0.2 0.021 16 6 33 .. 746 773 .. 746 774 .. 0.93 5 ? -0.4 0.1 3.4 2.6e+03 9 28 .. 991 1010 .. 991 1012 .. 0.84 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 7.1 TPR_8 16 dyeeAkeyyekalel 30 dy+ A ++++ +l++ FUN_001865-T2 628 DYKRALQSLQLCLRY 642 99**********986 PP == domain 2 score: 16.2 bits; conditional E-value: 1.6e-05 TPR_8 2 eayynlGliy.lklgdyeeAkeyyekaleldp 32 + y+ +G++y + l+dy++A e+y ka+++ + FUN_001865-T2 655 RCYNAMGNCYyHGLEDYNKALEFYSKAIKMTE 686 78999**7777*****************9976 PP == domain 3 score: 20.7 bits; conditional E-value: 6e-07 TPR_8 5 ynlGliylklgdyeeAkeyyekalel 30 +++G +y+ +g+y+eA+eyy++a++l FUN_001865-T2 703 NQIGTVYEGKGNYAEAVEYYKEAIRL 728 689*********************87 PP == domain 4 score: 6.5 bits; conditional E-value: 0.021 TPR_8 6 nlGliylklgdyeeAkeyyekaleldpd 33 nl+++yl + +++eA+e e+a e++++ FUN_001865-T2 746 NLANAYLYQDNFKEAVEPAERAFEIRKK 773 79********************999875 PP == domain 5 score: -0.4 bits; conditional E-value: 3.4 TPR_8 9 liylklgdyeeAkeyyekal 28 ++y++lg++e e++e l FUN_001865-T2 991 QLYIELGEKERIAEFLESLL 1010 69********9888888766 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.1 0.019 14 6 30 .. 620 642 .. 620 648 .. 0.81 2 ? 5.4 0.0 0.045 34 4 32 .. 659 686 .. 657 688 .. 0.82 3 ! 13.8 0.1 9e-05 0.068 5 28 .. 705 728 .. 703 733 .. 0.85 4 ? 6.0 0.1 0.028 21 4 25 .. 746 767 .. 745 776 .. 0.81 5 ? 0.8 0.0 1.4 1e+03 6 26 .. 990 1010 .. 987 1013 .. 0.88 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.019 TPR_7 6 ariyrklGdydeAirlyerlLalak 30 ++i+++ +dy++A++ ++ l++ FUN_001865-T2 620 GEIFCRARDYKRALQSLQL--CLRY 642 789***************9..5554 PP == domain 2 score: 5.4 bits; conditional E-value: 0.045 TPR_7 4 aLariyrk.lGdydeAirlyerlLalakdp 32 a++++y l+dy +A+++y + a+++++ FUN_001865-T2 659 AMGNCYYHgLEDYNKALEFYSK--AIKMTE 686 899997777***********99..666554 PP == domain 3 score: 13.8 bits; conditional E-value: 9e-05 TPR_7 5 LariyrklGdydeAirlyerlLal 28 ++ +y+ +G+y eA+++y+++++l FUN_001865-T2 705 IGTVYEGKGNYAEAVEYYKEAIRL 728 7899****************7755 PP == domain 4 score: 6.0 bits; conditional E-value: 0.028 TPR_7 4 aLariyrklGdydeAirlyerl 25 +La++y + +++eA++ er+ FUN_001865-T2 746 NLANAYLYQDNFKEAVEPAERA 767 8**************9866665 PP == domain 5 score: 0.8 bits; conditional E-value: 1.4 TPR_7 6 ariyrklGdydeAirlyerlL 26 +++y lG+ ++ ++++e lL FUN_001865-T2 990 EQLYIELGEKERIAEFLESLL 1010 689***************987 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 6.9e-08 5.2e-05 3 95 .. 132 243 .. 130 265 .. 0.71 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 6.9e-08 AAA 3 lyGppGtGKTllakavakel..gaefveisgselvsk.................yvgesekklrelfeeakkka...psvifiDEiDalakkrsss 76 l+G G+GKT++ak +++++ +++ + e ++ + +s++ +++++e+a ++ p ++++D++D+++ ++ FUN_001865-T2 132 LHGSEGVGKTACAKEICAKWpgRSHIFDLR--EAKDMravylkgmnmfglavpvGYIDSSSVVEKMLEQAFIESgglPVLFLLDNADQFTLGV-GK 224 99*****************95423333332..2222223455556666678888888999**********999999899999*******8888.55 PP AAA 77 eseeservvnaLlteldgf 95 e ++ + ++ ++l el ++ FUN_001865-T2 225 EGKNLKTAFMQFLGELTRY 243 5556666666666555544 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.0 0.1 0.0064 4.8 151 214 .. 665 730 .. 596 739 .. 0.63 2 ! 14.8 0.2 2.7e-05 0.02 100 216 .. 655 774 .. 649 775 .. 0.76 3 ! 12.4 0.0 0.00014 0.11 116 185 .. 758 826 .. 751 839 .. 0.93 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0064 TPR_NPHP3 151 yaqwgkfstaealykqaleiyenayGsd..helvakelealallyqkqdkhdlaeplkkravairk 214 y + +++a ++y +a++++e++ Gs h+ + + + ++y+ + + a k a+ + + FUN_001865-T2 665 YHGLEDYNKALEFYSKAIKMTEEISGSSecHYDLPVTKNQIGTVYEGKGNYAEAVEYYKEAIRLLE 730 333455666666666666666666665433555555555555566555555555555555554444 PP == domain 2 score: 14.8 bits; conditional E-value: 2.7e-05 TPR_NPHP3 100 dlyealGr.flkdlgllsqalpaLqraLeiRetaldP..DhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealall 192 y+a+G+ + + l ++al+ +a+ + e h + ++ q+ ++y+ g+++ a ++yk+a+ + e+ s + a la+ FUN_001865-T2 655 RCYNAMGNcYYHGLEDYNKALEFYSKAIKMTEEISGSseCHYDLPVTKNQIGTVYEGKGNYAEAVEYYKEAIRLLEKLKISGCPDEAFFQRNLANA 750 567777763566788888888888888887775543311355556688999************************987655555555556678888 PP TPR_NPHP3 193 yqkqdkhdlaeplkkravairkka 216 y qd ++ a +ra+ irkk+ FUN_001865-T2 751 YLYQDNFKEAVEPAERAFEIRKKQ 774 88899999999999*******995 PP == domain 3 score: 12.4 bits; conditional E-value: 0.00014 TPR_NPHP3 116 sqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvake 185 + a+++ +ra eiR +l DhP rs q + + g+ ++a +l k+a e+ ++ +h +v k FUN_001865-T2 758 KEAVEPAERAFEIRKKQL-GDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEMEKSLQSGNHSVVWKR 826 689**************8.5**************************************999999999775 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 1.3e-06 0.00096 3 54 .. 109 158 .. 107 172 .. 0.84 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 1.3e-06 AAA_16 3 vgReeeleaLlallervrsgrpplvlvsGeaGvGKSalvrellralera.alv 54 gR++ +++++ l+ +g+p+ v ++G GvGK+a ++e+ + +++ +++ FUN_001865-T2 109 QGRDDDIAKITGRLK---AGQPSPVNLHGSEGVGKTACAKEICAKWPGRsHIF 158 69*****99998887...899999*****************998777665555 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.1 2.7e-06 0.002 3 57 .. 705 767 .. 703 773 .. 0.92 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 2.7e-06 TPR_16 3 laraalaagdyddAaaaleaalrrn........PeaaaAllglGlallrqgrlaeAaaayraa 57 ++ + g+y++A++++++a+r P+ a ++++l+ a+l q ++ eA++ +++a FUN_001865-T2 705 IGTVYEGKGNYAEAVEYYKEAIRLLeklkisgcPDEAFFQRNLANAYLYQDNFKEAVEPAERA 767 57889999*************************************************777765 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 1.2e-06 0.00087 24 190 .. 639 811 .. 626 840 .. 0.75 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 1.2e-06 TPR_MalT 24 AreALallpeddllartlatlvlGea.sllqgdlesAlaalreaeala...rradslhvtllall.qqaellraqGqLhqAaetyqqalqlaqesk 114 + + ++ lpe ++ + ++G ++ ++d ++Al+ +++a++++ + h+ l + q + +++++G ++A e y++a++l ++ k FUN_001865-T2 639 CLRYIEELPEVNIQLTRCY-NAMGNCyYHGLEDYNKALEFYSKAIKMTeeiSGSSECHYDLPVTKnQIGTVYEGKGNYAEAVEYYKEAIRLLEKLK 733 5555555555554444444.456654156688*************9962113444457766555526667************************** PP TPR_MalT 115 lealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql..epaaaleayvllarvalaqGeleeAetllqraerl 190 + p +f ++ la+ ++ + + eA + ++++ ++ ++ + ++++ + Ge + A+ ll++a ++ FUN_001865-T2 734 ISGCPDEAFFQRNLANAYLYQDNFKEAVEPAERAFEIRKKQlgDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEM 811 *************************************99844566778888888888888899999999999998666 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.23 1.7e+02 18 32 .. 669 683 .. 668 689 .. 0.90 2 ! 17.0 0.1 9.1e-06 0.0068 14 37 .. 709 732 .. 703 750 .. 0.88 3 ? 1.0 0.0 0.87 6.5e+02 3 18 .. 800 815 .. 799 818 .. 0.86 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.23 MIT 18 gnyeeAlelYkeale 32 ++y +Ale+Y++a++ FUN_001865-T2 669 EDYNKALEFYSKAIK 683 68**********996 PP == domain 2 score: 17.0 bits; conditional E-value: 9.1e-06 MIT 14 eDnagnyeeAlelYkealelLlqa 37 ++ +gny+eA+e+Ykea++lL ++ FUN_001865-T2 709 YEGKGNYAEAVEYYKEAIRLLEKL 732 6889****************9875 PP == domain 3 score: 1.0 bits; conditional E-value: 0.87 MIT 3 kAlelvkkAveeDnag 18 kAl+l+kkA e++++ FUN_001865-T2 800 KALDLLKKAWEMEKSL 815 9**********99875 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.1 0.0064 4.8 4 40 .. 626 662 .. 625 662 .. 0.96 2 ? -0.5 0.0 3 2.2e+03 5 20 .. 669 684 .. 666 698 .. 0.82 3 ! 7.6 0.4 0.0089 6.7 5 46 .. 713 762 .. 710 772 .. 0.78 4 ? -0.4 0.0 2.8 2.1e+03 8 21 .. 799 812 .. 795 814 .. 0.82 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0064 TPR_19 4 egdydeAlalLeqalaedPdnaearllLArallalgr 40 + dy++Al+ L+ l + + +e+++ L r++ a+g+ FUN_001865-T2 626 ARDYKRALQSLQLCLRYIEELPEVNIQLTRCYNAMGN 662 68********************************997 PP == domain 2 score: -0.5 bits; conditional E-value: 3 TPR_19 5 gdydeAlalLeqalae 20 +dy++Al+++ +a+++ FUN_001865-T2 669 EDYNKALEFYSKAIKM 684 79**********9876 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0089 TPR_19 5 gdydeAlalLeqalae........dPdnaearllLArallalgrldeAea 46 g+y+eA++++++a+ + Pd a + +LA+a+l +++++eA + FUN_001865-T2 713 GNYAEAVEYYKEAIRLleklkisgCPDEAFFQRNLANAYLYQDNFKEAVE 762 78888888888877664444444477788888899999999999999975 PP == domain 4 score: -0.4 bits; conditional E-value: 2.8 TPR_19 8 deAlalLeqalaed 21 ++Al lL++a++++ FUN_001865-T2 799 KKALDLLKKAWEME 812 789*******9986 PP >> DUF3856 Domain of Unknown Function (DUF3856) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.04 30 63 135 .. 621 690 .. 608 696 .. 0.79 2 ! 10.3 0.1 0.00094 0.7 22 129 .. 712 811 .. 704 820 .. 0.82 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.04 DUF3856 63 ealvklgrfeealhsaekalryfnrrGelnqdeGklwiaavfsralaleglGrkeealkafkkagemiaerkG 135 e +++ + ++ al+s + +lry++ e+n + + + a +gl ++al+++ ka +m +e G FUN_001865-T2 621 EIFCRARDYKRALQSLQLCLRYIEELPEVNIQLTRCYNAMGNCY---YHGLEDYNKALEFYSKAIKMTEEISG 690 789999******************99999988888776655444...44555567788888888888887666 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00094 DUF3856 22 ageyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekalryfnrrGelnqdeGklwiaavfsralaleglGrke 117 +g+y ea e ++ a+ + + + d +a+ l++a++ +f+ea++ ae+a++ + +l d + ++f++ lG+++ FUN_001865-T2 712 KGNYAEAVEYYKEAIRLLEKLKISGCPD----EAFFQRNLANAYLYQDNFKEAVEPAERAFEIR--KKQLG-DH-PDTVRSIFQQGFIETCLGESK 799 5789999999999999999998888888....577789********************997653..33443.32.235788999999999999999 PP DUF3856 118 ealkafkkagem 129 +al+ +kka em FUN_001865-T2 800 KALDLLKKAWEM 811 999999999999 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 6.1 4.6e+03 11 29 .. 665 683 .. 655 687 .. 0.82 2 ? 7.8 0.0 0.012 9.3 8 30 .. 706 728 .. 700 732 .. 0.87 3 ? 7.0 0.1 0.022 16 4 30 .. 744 770 .. 742 776 .. 0.88 4 ? -0.2 0.0 4.8 3.6e+03 12 29 .. 793 810 .. 785 816 .. 0.83 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 6.1 TPR_14 11 llalGdpdeAlellerala 29 + l d+ +Ale + +a++ FUN_001865-T2 665 YHGLEDYNKALEFYSKAIK 683 566899*********9987 PP == domain 2 score: 7.8 bits; conditional E-value: 0.012 TPR_14 8 arallalGdpdeAlelleralal 30 + +++ G+++eA+e++++a++l FUN_001865-T2 706 GTVYEGKGNYAEAVEYYKEAIRL 728 6789999*************986 PP == domain 3 score: 7.0 bits; conditional E-value: 0.022 TPR_14 4 wlalarallalGdpdeAlelleralal 30 ++ la+a+l +++++eA+e +era + FUN_001865-T2 744 QRNLANAYLYQDNFKEAVEPAERAFEI 770 5679*******************9875 PP == domain 4 score: -0.2 bits; conditional E-value: 4.8 TPR_14 12 lalGdpdeAlellerala 29 lG+ ++Al+ll++a + FUN_001865-T2 793 TCLGESKKALDLLKKAWE 810 5689**********9976 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 2.6e-05 0.019 2 50 .. 112 159 .. 111 163 .. 0.91 2 ? -3.0 0.0 8.5 6.4e+03 125 145 .. 248 267 .. 245 288 .. 0.67 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.6e-05 NB-ARC 2 eksvekviekLlekdelqivalvGmgGvGKttLakeifnklsevegrFd 50 ++++ k+ ++L +++ v l+G GvGKt akei k ++ Fd FUN_001865-T2 112 DDDIAKITGRLK-AGQPSPVNLHGSEGVGKTACAKEICAKWPGRSHIFD 159 678999*****9.99************************9998888888 PP == domain 2 score: -3.0 bits; conditional E-value: 8.5 NB-ARC 125 renkskvllTtRseevaeavk 145 + +++++llT+R +v ea k FUN_001865-T2 248 KTRELRILLTSRT-SVKEASK 267 567899*****96.4544433 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 2.6e-05 0.019 9 108 .. 131 241 .. 124 264 .. 0.76 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2.6e-05 AAA_22 9 vltGesGtGKTtllrrlleqldeeddsvvlvelpsstspkdllrellralglelek.elskeell.aalqealkalaa.ravliiDEaqnl..... 96 l+G +G+GKT +++++ ++ + + ++l++ ++ ++++ + + +gl + +++ ++ ++l++a+ +++ ++++++D+a+ + FUN_001865-T2 131 NLHGSEGVGKTACAKEICAKW---PGRSHIFDLREAKDMRAVYLKGMNMFGLAVPVgYIDSSSVVeKMLEQAFIESGGlPVLFLLDNADQFtlgvg 223 589****************98...8888999999999999999999999998777775677777769999999999999***********955555 PP AAA_22 97 .s.....eelleeLrsll 108 + +++++L +l FUN_001865-T2 224 kEgknlkTAFMQFLGELT 241 413344444555554444 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.4 2.3e-05 0.017 3 33 .. 656 683 .. 654 685 .. 0.90 2 ? 4.7 0.0 0.098 74 18 33 .. 712 727 .. 704 728 .. 0.83 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.3e-05 Sel1 3 AqyrLGylylyGlgvpkDpekAlewyekAAe 33 +++ +G +y++G D++kAle+y+kA + FUN_001865-T2 656 CYNAMGNCYYHG---LEDYNKALEFYSKAIK 683 6789********...69************87 PP == domain 2 score: 4.7 bits; conditional E-value: 0.098 Sel1 18 pkDpekAlewyekAAe 33 + ++ +A+e+y+ A + FUN_001865-T2 712 KGNYAEAVEYYKEAIR 727 669***********87 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.1 1.8 1.3e+03 4 27 .. 617 640 .. 615 642 .. 0.83 2 ? 6.1 0.0 0.039 29 6 28 .. 660 683 .. 659 684 .. 0.93 3 ? 7.6 0.1 0.012 9.3 6 28 .. 705 727 .. 704 728 .. 0.90 4 ? 0.6 0.0 2.3 1.7e+03 5 21 .. 746 762 .. 745 768 .. 0.88 5 ? 0.5 0.0 2.4 1.8e+03 9 28 .. 992 1011 .. 991 1013 .. 0.90 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.8 TPR_6 4 lklalsylelgdkdeAkaalqrli 27 + ++++ ++ d+++A++ lq ++ FUN_001865-T2 617 YIEGEIFCRARDYKRALQSLQLCL 640 55689999999*********9766 PP == domain 2 score: 6.1 bits; conditional E-value: 0.039 TPR_6 6 lalsyle.lgdkdeAkaalqrlik 28 ++ +y+ l d+++A++++ + ik FUN_001865-T2 660 MGNCYYHgLEDYNKALEFYSKAIK 683 799****99***********9987 PP == domain 3 score: 7.6 bits; conditional E-value: 0.012 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 ++ y+ g+++eA++++++ i+ FUN_001865-T2 705 IGTVYEGKGNYAEAVEYYKEAIR 727 7999**999**********9885 PP == domain 4 score: 0.6 bits; conditional E-value: 2.3 TPR_6 5 klalsylelgdkdeAka 21 +la +yl +++++eA++ FUN_001865-T2 746 NLANAYLYQDNFKEAVE 762 589************97 PP == domain 5 score: 0.5 bits; conditional E-value: 2.4 TPR_6 9 sylelgdkdeAkaalqrlik 28 +y+elg+k++ +++l++l++ FUN_001865-T2 992 LYIELGEKERIAEFLESLLS 1011 799**************987 PP >> nSTAND3 Novel STAND NTPase 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 0.0 0.002 1.5 22 61 .. 132 170 .. 127 178 .. 0.85 2 ? 0.8 0.1 0.65 4.9e+02 101 128 .. 247 276 .. 220 301 .. 0.65 3 ? 1.1 0.2 0.51 3.8e+02 63 98 .. 1057 1091 .. 1031 1135 .. 0.73 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.002 nSTAND3 22 itGepGiGKttlaemLalklldegyevvkissieelekvl 61 + G+ G+GKt++a+ +++k+ ++ +++ +++ +++++v+ FUN_001865-T2 132 LHGSEGVGKTACAKEICAKWPGRS-HIFDLREAKDMRAVY 170 78*****************99975.888888888888776 PP == domain 2 score: 0.8 bits; conditional E-value: 0.65 nSTAND3 101 sknk..klilTtReyilnqakekseklerl 128 sk++ +++lT+R+ + + k + +l+ l FUN_001865-T2 247 SKTRelRILLTSRTSVKEASKVEDYELQPL 276 4444425*********99999885555555 PP == domain 3 score: 1.1 bits; conditional E-value: 0.51 nSTAND3 63 pnkkqvflfDDflGetslekksknedskllsfikri 98 k+ +++f+D + ++ + ++++ ++l++ i + FUN_001865-T2 1057 FAKEALIFFEDLWTVKFK-EMNTRKTKQLFRDIMDW 1091 345679*******98665.55667788888888554 PP >> Iml2-TPR_39 Iml2/Tetratricopeptide repeat protein 39 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.2 0.38 2.9e+02 269 390 .. 618 745 .. 562 758 .. 0.70 2 ? 11.7 0.0 0.00015 0.11 244 313 .. 762 831 .. 749 835 .. 0.92 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.38 Iml2-TPR_39 269 feariellkgnldeAlelleeliesqselkqv..hhlcyfelalclvf..lhkykqaansallLv....keskwSkalYtYlkaacllelykeeek 356 e+ i + ++Al++l+ ++ +el +v + + ++ + ++ + l++y++a++ ++ + ++s +S + Y + +++++ e FUN_001865-T2 618 IEGEIFCRARDYKRALQSLQLCLRYIEELPEVniQLTRCYNAMGNCYYhgLEDYNKALEFYSKAIkmteEISGSSECHYD--LPVTKNQIGTVYEG 711 47777777888899999999999888888876215567788887776623579999977654433000145667777665..56677777777777 PP Iml2-TPR_39 357 keakekavellrevpklkqkiagkslplekFaar 390 k + ++ave+ +e+ l +k + p e F r FUN_001865-T2 712 KGNYAEAVEYYKEAIRLLEKLKISGCPDEAFFQR 745 7777899999999999999988899999988877 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00015 Iml2-TPR_39 244 apleeaeelLkklrkryPkgallllfeariellkgnldeAlelleeliesqselkqvhhlcyfelalclv 313 p e+a e+ kk++ +P+ + +++++ ie g+ ++Al+ll++++e +++l+ +h +++ + + ++ FUN_001865-T2 762 EPAERAFEIRKKQLGDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEMEKSLQSGNHSVVWKRIIDHI 831 5789999999******************************************************998886 PP >> ATPase_2 ATPase domain predominantly from Archaea # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 0.00015 0.11 4 44 .. 111 151 .. 109 297 .. 0.85 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00015 ATPase_2 4 RekelkeleelaergtneiiviYGpegcGKtallkeiienl 44 R+ + ++ ++ g+ +++ + G eg+GKta kei + FUN_001865-T2 111 RDDDIAKITGRLKAGQPSPVNLHGSEGVGKTACAKEICAKW 151 8999********************************98876 PP >> TPR_IF140_C IF140 C-terminal TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.57 4.3e+02 54 84 .. 67 97 .. 63 118 .. 0.72 2 ? 1.5 0.0 0.69 5.2e+02 19 40 .. 627 648 .. 625 656 .. 0.87 3 ? 8.2 0.2 0.0061 4.6 3 43 .. 653 693 .. 651 710 .. 0.80 4 ? 3.4 0.2 0.18 1.3e+02 20 41 .. 714 735 .. 708 774 .. 0.82 5 ? 3.2 0.0 0.2 1.5e+02 23 88 .. 793 859 .. 791 865 .. 0.75 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.57 TPR_IF140_C 54 kekielikkfveakklyeedpeealkqceeL 84 k k++li++fv+ k++ ee+ ++ ++ ++ FUN_001865-T2 67 KAKLTLIREFVASKSINEEEIKKIIDNYTQV 97 67999****************9998766554 PP == domain 2 score: 1.5 bits; conditional E-value: 0.69 TPR_IF140_C 19 qdYekAlgalkealkclskake 40 +dY++Al+ l+ +l+++++ e FUN_001865-T2 627 RDYKRALQSLQLCLRYIEELPE 648 9***************998765 PP == domain 3 score: 8.2 bits; conditional E-value: 0.0061 TPR_IF140_C 3 LasFYeacAqveideyqdYekAlgalkealkclskakekse 43 L + Y+a+ + dY+kAl+ +++a+k+ ++++ +se FUN_001865-T2 653 LTRCYNAMGNCYYHGLEDYNKALEFYSKAIKMTEEISGSSE 693 66778888888889999****************99987654 PP == domain 4 score: 3.4 bits; conditional E-value: 0.18 TPR_IF140_C 20 dYekAlgalkealkclskakek 41 +Y +A++ +kea++ l+k k + FUN_001865-T2 714 NYAEAVEYYKEAIRLLEKLKIS 735 9*****************9865 PP == domain 5 score: 3.2 bits; conditional E-value: 0.2 TPR_IF140_C 23 kAlgalkealkclskakeksekekekk.leelkekielikkfveakklyeedpeealkqceeLleep 88 +lg k+al l+ka e +++ ++ + k+ i++i f e + ++ +eeal+ c+++ +e+ FUN_001865-T2 793 TCLGESKKALDLLKKAWEMEKSLQSGNhSVVWKRIIDHIIYFTEGDNEKKKFEEEALAFCQRFWKEE 859 5667777888888888765555555440445688899**********9999**********999875 PP >> NACHT NACHT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.2 0.00063 0.48 2 27 .. 129 154 .. 128 292 .. 0.67 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00063 NACHT 2 tvilqGeaGsGKTtLlqklalawaeg 27 +v l+G G+GKT+ +++++ +w + FUN_001865-T2 129 PVNLHGSEGVGKTACAKEICAKWPGR 154 5789*******************654 PP >> nSTAND6 Novel STAND NTPase 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.00047 0.35 3 43 .. 110 152 .. 108 171 .. 0.82 2 ? -1.5 0.0 4.5 3.4e+03 90 145 .. 459 513 .. 417 516 .. 0.67 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00047 nSTAND6 3 GRekllkklvakLk..ekpillvyGlrGnGKstlieelgkkaa 43 GR++ ++k++ +Lk + + + ++G G+GK++ +e+++k + FUN_001865-T2 110 GRDDDIAKITGRLKagQPSPVNLHGSEGVGKTACAKEICAKWP 152 9************833456799****************98866 PP == domain 2 score: -1.5 bits; conditional E-value: 4.5 nSTAND6 90 aaelkrrYpaarpafiwidrAhllldesgfrnselrdlLrglakalpqwrlvlElr 145 ++++ + Y +ar++f + +ll+ +gf++s+ + + +++ ++++ +El+ FUN_001865-T2 459 DEKFLESYTEARKRFCD-HFMSQLLTIAGFVDSNFVKAFNMFTSDDANYKFAIELS 513 46677888888888864.33456788888888888777777777777777777765 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.021 16 7 23 .. 668 684 .. 664 687 .. 0.84 2 ? 7.7 3.4 0.0051 3.9 7 23 .. 712 728 .. 706 755 .. 0.83 3 ? -2.3 0.0 7.2 5.4e+03 2 15 .. 749 762 .. 748 763 .. 0.90 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.021 TPR_11 7 qGkyeeAieaYkkAlkl 23 + +y++A+e Y+kA+k FUN_001865-T2 668 LEDYNKALEFYSKAIKM 684 679************96 PP == domain 2 score: 7.7 bits; conditional E-value: 0.0051 TPR_11 7 qGkyeeAieaYkkAlkl 23 +G+y eA+e Yk+A++l FUN_001865-T2 712 KGNYAEAVEYYKEAIRL 728 8**************98 PP == domain 3 score: -2.3 bits; conditional E-value: 7.2 TPR_11 2 dayyeqGkyeeAie 15 +ay q +++eA+e FUN_001865-T2 749 NAYLYQDNFKEAVE 762 99**********97 PP >> COP9_hel_rpt COP9 signalosome complex subunit 3, N-terminal helical repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.1 0.00064 0.48 133 192 .. 578 640 .. 529 646 .. 0.75 2 ? 4.0 0.3 0.059 45 167 195 .. 657 685 .. 643 689 .. 0.83 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00064 COP9_hel_rpt 133 LlakclkpalelLdvditkisk..ekgkvdakyfL.lYyYYGGmiytalknyerAlyffevav 192 L + k a e+L+ + ++++k +k+ ++ k lY+Y G i+ ++y+rAl+ +++++ FUN_001865-T2 578 LDLNGPKEAFEVLQGEAHSLEKlqDKTVTNFKLTQgLYFYIEGEIFCRARDYKRALQSLQLCL 640 5555667788888888888887323333344433248***********************997 PP == domain 2 score: 4.0 bits; conditional E-value: 0.059 COP9_hel_rpt 167 YyYYGGmiytalknyerAlyffevavttp 195 Y G y +l +y++Al+f+ a+ + FUN_001865-T2 657 YNAMGNCYYHGLEDYNKALEFYSKAIKMT 685 55578889****************99875 PP >> Sigma54_activ_2 Sigma-54 interaction domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.0006 0.45 6 61 .. 114 167 .. 110 201 .. 0.82 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0006 Sigma54_activ_2 6 liselkkrlekiaqsklpvfliGekGsGkelvaryLhknstpwveitdveklakap 61 i+++ rl+ a++ +pv l G +G Gk+ +a+ ++ + ++i+d+ + ++ FUN_001865-T2 114 DIAKITGRLK--AGQPSPVNLHGSEGVGKTACAKEICAKWPGRSHIFDLREAKDMR 167 5777777777..5899*******************999887779999988877776 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 2.3 0.11 84 26 81 .. 614 680 .. 591 681 .. 0.76 2 ? 8.8 0.2 0.0038 2.8 4 57 .. 721 776 .. 718 808 .. 0.85 3 ? -0.1 0.0 2.2 1.6e+03 36 57 .. 795 816 .. 779 819 .. 0.89 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.11 ANAPC3 26 ayll..AqclflngqykrAyellrkaklneksl........gcryllAqcll.kLkkykeAldaLek 81 +y + ++ ++++ +ykrA++ l+ + + + l +c ++ c++ L+ y++Al+ + k FUN_001865-T2 614 LYFYieGEIFCRARDYKRALQSLQLCLRYIEELpevniqltRCYNAMGNCYYhGLEDYNKALEFYSK 680 5555569999*********999888855555555667777799999999998789999999988765 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0038 ANAPC3 4 qyknAiflaerllaaepespedayl...lAqclflngqykrAyellrka.klnekslg 57 yk+Ai l e+l + p+ a+ lA++++ + ++k+A+e ++a ++++k lg FUN_001865-T2 721 YYKEAIRLLEKLK--ISGCPDEAFFqrnLANAYLYQDNFKEAVEPAERAfEIRKKQLG 776 69***********..88889999985666*******************9888887775 PP == domain 3 score: -0.1 bits; conditional E-value: 2.2 ANAPC3 36 ngqykrAyellrkaklnekslg 57 +g+ k+A++ll+ka++ eksl+ FUN_001865-T2 795 LGESKKALDLLKKAWEMEKSLQ 816 68899*********99999986 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.1 4.3 3.2e+03 40 84 .. 57 105 .. 40 128 .. 0.62 2 ? 4.6 0.1 0.066 49 14 30 .. 670 686 .. 658 698 .. 0.84 3 ? 8.7 0.1 0.0036 2.7 4 106 .. 704 815 .. 702 823 .. 0.68 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 4.3 ARM_TT21_4th 40 eLllkLkqydkaekvlkqaleeek...skdleslmeev.klllLlakvr 84 +L++k + ka+ +l ++ +k ++++++++++ ++ +L + + FUN_001865-T2 57 NLFFKFGYVSKAKLTLIREFVASKsinEEEIKKIIDNYtQVNTLQIESE 105 6899999999999888877766541224566666554314444444443 PP == domain 2 score: 4.6 bits; conditional E-value: 0.066 ARM_TT21_4th 14 qYkkAinYYeaalksse 30 +Y+kA ++Y +a+k++e FUN_001865-T2 670 DYNKALEFYSKAIKMTE 686 7************9876 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0036 ARM_TT21_4th 4 kiGqalvktHqYkkAinYYeaalk......sse...qksLrldLAeLllkLkqydkaekvlkqaleeekskdleslmeevklllLlakvrk.sgkk 89 +iG+ + +Y+ A++YY++a++ +s+ +++++ +LA+ +l ++++a + ++a e +k k+l ++v+ + +++ g++ FUN_001865-T2 704 QIGTVYEGKGNYAEAVEYYKEAIRlleklkISGcpdEAFFQRNLANAYLYQDNFKEAVEPAERAFEIRK-KQLGDHPDTVRSIFQQGFIETcLGES 798 57777777779***********87333332222222567888888888888888888888888887665.45555566666666666666435777 PP ARM_TT21_4th 90 eealetLkkakelqarv 106 ++al+ Lkka e+++ + FUN_001865-T2 799 KKALDLLKKAWEMEKSL 815 77888888888877665 PP >> Consortin_N Consortin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.041 31 14 35 .. 621 642 .. 620 646 .. 0.84 2 ? 1.3 0.1 0.63 4.7e+02 16 28 .. 665 677 .. 652 680 .. 0.79 3 ? 0.7 0.0 0.97 7.3e+02 5 28 .. 698 721 .. 695 728 .. 0.87 4 ? -0.5 0.1 2.3 1.7e+03 11 27 .. 746 762 .. 744 764 .. 0.90 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.041 Consortin_N 14 eayfleedYekAiqFiqlEklY 35 e++ + +dY++A+q +ql Y FUN_001865-T2 621 EIFCRARDYKRALQSLQLCLRY 642 899**************96666 PP == domain 2 score: 1.3 bits; conditional E-value: 0.63 Consortin_N 16 yfleedYekAiqF 28 y+ edY+kA++F FUN_001865-T2 665 YHGLEDYNKALEF 677 4667*******99 PP == domain 3 score: 0.7 bits; conditional E-value: 0.97 Consortin_N 5 LPqcLHqiaeayfleedYekAiqF 28 LP qi +y + +Y A+++ FUN_001865-T2 698 LPVTKNQIGTVYEGKGNYAEAVEY 721 7777789**************985 PP == domain 4 score: -0.5 bits; conditional E-value: 2.3 Consortin_N 11 qiaeayfleedYekAiq 27 ++a+ay +++++ A++ FUN_001865-T2 746 NLANAYLYQDNFKEAVE 762 78*************95 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.3 0.34 2.6e+02 123 161 .. 648 687 .. 620 692 .. 0.80 2 ? 6.9 0.5 0.0098 7.4 133 161 .. 703 731 .. 696 771 .. 0.85 3 ? 0.2 0.0 1 7.8e+02 109 161 .. 762 814 .. 740 820 .. 0.76 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.34 ARM_TT21_C 123 kynkscakAyellGlia.ekeqsykdAaenYekAWklske 161 + n ++ y+ +G ++ + y++A e Y kA k+++e FUN_001865-T2 648 EVNIQLTRCYNAMGNCYyHGLEDYNKALEFYSKAIKMTEE 687 56888999******997256799************99876 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0098 ARM_TT21_C 133 ellGliaekeqsykdAaenYekAWklske 161 + +G+++e + +y +A+e+Y++A +l ++ FUN_001865-T2 703 NQIGTVYEGKGNYAEAVEYYKEAIRLLEK 731 578********************998765 PP == domain 3 score: 0.2 bits; conditional E-value: 1 ARM_TT21_C 109 gkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklske 161 + ++ A e+ kk l + ++ G+i + k+A + +kAW+++k+ FUN_001865-T2 762 EPAERAFEIRKKQLGDHPDTVRSIFQQGFIETCLGESKKALDLLKKAWEMEKS 814 45667777777777777788888888899999999999999999999998865 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.2 3.2 2.4e+03 9 18 .. 511 520 .. 511 523 .. 0.92 2 ? -1.3 0.0 3 2.2e+03 21 31 .. 668 678 .. 668 681 .. 0.83 3 ? 4.8 0.0 0.036 27 15 35 .. 713 733 .. 712 734 .. 0.93 4 ? 5.3 0.2 0.026 20 12 33 .. 752 773 .. 747 775 .. 0.88 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 3.2 SHNi-TPR 9 EiSLEnenFe 18 E+S+E e+F+ FUN_001865-T2 511 ELSMEPEFFS 520 89*******6 PP == domain 2 score: -1.3 bits; conditional E-value: 3 SHNi-TPR 21 vkDlrkaLeLr 31 ++D+ kaLe + FUN_001865-T2 668 LEDYNKALEFY 678 58******966 PP == domain 3 score: 4.8 bits; conditional E-value: 0.036 SHNi-TPR 15 enFeqAvkDlrkaLeLreell 35 n+ +Av+ +++a+ L+e+l+ FUN_001865-T2 713 GNYAEAVEYYKEAIRLLEKLK 733 69*****************97 PP == domain 4 score: 5.3 bits; conditional E-value: 0.026 SHNi-TPR 12 LEnenFeqAvkDlrkaLeLree 33 L ++nF++Av+ ++a e+r + FUN_001865-T2 752 LYQDNFKEAVEPAERAFEIRKK 773 5689***************986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1562 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1462 (0.0572323); expected 510.9 (0.02) Passed bias filter: 848 (0.0331963); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 34 (0.00133098); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 34 [number of targets reported over threshold] # CPU time: 0.57u 0.44s 00:00:01.01 Elapsed: 00:00:00.44 # Mc/sec: 14419.29 // Query: FUN_001866-T1 [L=130] Description: FUN_001866 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.017 15.6 0.1 0.018 15.5 0.1 1.1 1 DUF3074 Protein of unknown function (DUF3074) Domain annotation for each model (and alignments): >> DUF3074 Protein of unknown function (DUF3074) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.1 6.9e-07 0.018 42 104 .. 15 90 .. 4 113 .. 0.72 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 6.9e-07 DUF3074 42 aerleew....vev..eg...weevklevvelshkfpkpltpRdFvvllltakseeeeessee.ee.ae..fvvvs 104 + le++ +e+ ++ ++ kl++++ + + l++R F+v+ +t +s+++++ +++ ++ a+ f++v+ FUN_001866-T1 15 VTMLEKYvltiLELtwNQrlgHKKTKLNICHNMLTSSTQLQNRSFHVVEITRTSSKSQKMKNArAKsAKvlFFIVK 90 555555543332223311445789999999999999999***********99998888777663334224566665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1483 (0.0580544); expected 510.9 (0.02) Passed bias filter: 728 (0.0284987); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1286.16 // Query: FUN_001867-T1 [L=870] Description: FUN_001867 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-94 315.7 0.0 1.1e-93 314.3 0.0 1.8 1 Kinesin Kinesin motor domain 1.6e-36 125.0 0.6 1.6e-36 125.0 0.6 2.4 2 MKLP1_Arf_bdg Arf6-interacting domain of mitotic kinesin-lik 9.4e-19 68.3 0.3 2e-16 60.7 0.0 3.3 3 Microtub_bd Microtubule binding ------ inclusion threshold ------ 0.23 12.2 2.7 0.96 10.2 2.7 2.1 1 Sas-6_C_CC Spindle assembly abnormal protein 6 homolog, C 0.84 8.9 3.2 2.2 7.6 2.7 1.8 2 DUF6212 Family of unknown function (DUF6212) 0.9 10.1 13.5 0.047 14.3 6.5 2.3 2 Sec10_N Exocyst complex component Sec10, N-terminal 1.3 9.4 6.3 1.2 9.6 0.8 2.7 2 XLF_CC XLF protein coiled-coil region 1.9 9.0 7.6 0.12 12.9 0.8 2.5 3 DASH_Dad4 DASH complex subunit Dad4 2 8.3 12.6 4.2 7.2 12.6 1.6 1 MIF4G_like_2 MIF4G like 2.1 9.5 13.4 2.1 9.5 4.2 3.1 2 SlyX SlyX 2.1 9.0 24.1 0.25 12.0 6.1 4.3 4 bZIP_1 bZIP transcription factor 5.9 7.3 7.8 9.8 6.5 0.2 3.0 3 TseH Type VI secretion system effector TseH-like 8.1 5.6 14.5 14 4.7 14.5 1.3 1 FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalyti Domain annotation for each model (and alignments): >> Kinesin Kinesin motor domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 314.3 0.0 5.8e-97 1.1e-93 1 326 [. 37 450 .. 37 451 .. 0.96 Alignments for each domain: == domain 1 score: 314.3 bits; conditional E-value: 5.8e-97 Kinesin 1 RvrPlnekekeekeeeiveveeeekeeekekkkkkkkekekkftFdkvfdeeatqeevyeevakplvesvleGynvtifaYGqtgsGKTyTmegse 96 R+rPl ++e+e+ + + ++ + ++ +++ k+ ++ e+++tF+kv+de++tq+ ++++va p+v+++++G n+ if+YG tgsGKT+Tm+gs FUN_001867-T1 37 RIRPLGNNEEESCVQIVSDTILQLTAPKNSAGYKSGHRLETQHTFKKVYDEKTTQKVLFDSVAYPVVDDLIHGKNGLIFTYGITGSGKTHTMTGS- 131 99********99999999988888888999999999999*******************************************************8. PP Kinesin 97 eeerGiipraleelFeeiekekek....................................................................esef 124 +++G++pr+l+ +F++i + ++ ++++ FUN_001867-T1 132 PSDSGLLPRCLDVIFNSIGELQAAryvfkpdkangidiqneheaklekekrereaalqalpptagsrnrnadnefsdlirvpetgivnevdeDNSY 227 899****************999889*******************************************************************999* PP Kinesin 125 svkvsylEiYnekirDLLskk.......kkkkkleiredkkkgvvvkgltevevksaeevlellelgeknrkvaatklneesSRSHavftitveqk 213 v vsy+EiYn+ i+DLL+++ k + ++red++++++v+g+tevevks+ee++ ++ +g+k+r+va+t ln+esSRSH+vf +++ q FUN_001867-T1 228 AVFVSYFEIYNNYIYDLLDETpvdpicaKPPASKNLREDNNRNMYVSGVTEVEVKSTEEAYGVFWKGQKKRRVANTVLNRESSRSHSVFAVKLVQG 323 **************************986666789************************************************************9 PP Kinesin 214 nkeeeee...k....vktsklnLvDLAGsErvsktgaaegerlkEakniNkSLlaLgnvisaLaek........kskhipYrdSkLTrlLqdsLgG 294 + + e + +s+l+L+DLAGsEr+++t+ a+g+rl+Ea niN SL++L+++++ L+e+ + k +pYrdSkLT+l+++ + G FUN_001867-T1 324 PLDPDGEevlQdkdqLAVSTLSLCDLAGSERTNRTK-AGGDRLREAGNINASLMTLRTCMEMLRENqgsiengmAPKIVPYRDSKLTHLFKNFFDG 418 99998885551567799*******************.69**********************************999******************** PP Kinesin 295 nsktlmivtispsssnleetlstlrfAsrake 326 + k+ m+v+++p+s++++e++++++fA+ +++ FUN_001867-T1 419 EGKVRMVVCLNPNSDDYDESVHVMKFAEVTQD 450 ***************************98775 PP >> MKLP1_Arf_bdg Arf6-interacting domain of mitotic kinesin-like protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 1.2 9.2 1.8e+04 34 69 .. 590 624 .. 571 634 .. 0.61 2 ! 125.0 0.6 8e-40 1.6e-36 3 104 .. 716 816 .. 714 819 .. 0.93 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 9.2 MKLP1_Arf_bdg 34 pqlkrkksvikltkpkekalakaskYvLthqeqdsd 69 +++++ +k+++ e ++ k +Y L +q++ d FUN_001867-T1 590 ALTQKNEMLQKTAELYESDK-KELQYELDDQKKRAD 624 44443444444444444444.666787777776555 PP == domain 2 score: 125.0 bits; conditional E-value: 8e-40 MKLP1_Arf_bdg 3 vnpr.hrrsrsagekwldHkPesnvdlgtilqpqlkrkksvikltkpkekalakaskYvLthqeqdsdGeieTkliKgdvlktrgGgaqvvfndie 97 +++r hrrs+s+ ++w++HkP+++++++t+lqp+lk +k++++ ++ k++++++a++YvL hqe+ds Gei+Tk+iKg+v+kt++Gg++++f+++e FUN_001867-T1 716 AKARhHRRSKSS-DCWIEHKPATHMETDTVLQPSLK-NKKTVSRPEGKDFKDTNATNYVLAHQEEDSGGEIQTKMIKGEVYKTASGGHSIQFTEVE 809 555549999999.***********************.788889999************************************************** PP MKLP1_Arf_bdg 98 tLkqesp 104 tLk +s FUN_001867-T1 810 TLKTRSD 816 ***9986 PP >> Microtub_bd Microtubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.7 0.0 1e-19 2e-16 4 137 .. 17 159 .. 15 176 .. 0.79 2 ? 3.7 0.1 0.038 75 132 155 .] 222 245 .. 203 245 .. 0.86 3 ? -2.6 0.0 3.4 6.6e+03 18 43 .. 418 446 .. 413 473 .. 0.70 Alignments for each domain: == domain 1 score: 60.7 bits; conditional E-value: 1e-19 Microtub_bd 4 eetlRrkleNsiqelkGniRvfarvrpeeeke.aakikypdets........esakgeekkkkksfkFdrvfpkeseqeevfeeisq.lvqsaldg 89 +t Rr++ N++++ + v++r+rp ++e + +++ ++t + ++ ++ + +++F +v++++++q+ +f+ + + v+ ++g FUN_001867-T1 17 TKTPRRTVSNKLKD---PVEVYCRIRPLGNNEeESCVQIVSDTIlqltapknSAGYKSGHRLETQHTFKKVYDEKTTQKVLFDSVAYpVVDDLIHG 109 56789999998776...699********999555566666655566666654445555688999*********************983556666** PP Microtub_bd 90 ynvcifaygqTGsGKtyTmeg..eedgmipraveeifefiselkekgwky 137 +n if+yg TGsGKt+Tm+g +++g +pr ++ if+ i el+ + FUN_001867-T1 110 KNGLIFTYGITGSGKTHTMTGspSDSGLLPRCLDVIFNSIGELQAARYVF 159 *********************999****************9996544444 PP == domain 2 score: 3.7 bits; conditional E-value: 0.038 Microtub_bd 132 ekgwkyeielqfveiynesinDlL 155 ++ +y + +++ eiyn+ i DlL FUN_001867-T1 222 DEDNSYAVFVSYFEIYNNYIYDLL 245 45689******************8 PP == domain 3 score: -2.6 bits; conditional E-value: 3.4 Microtub_bd 18 lkGniRvfarvrpeeeke...aakikypd 43 +G++R+ + ++p++++ + +k+++ FUN_001867-T1 418 GEGKVRMVVCLNPNSDDYdesVHVMKFAE 446 57999*99999999998533333444443 PP >> Sas-6_C_CC Spindle assembly abnormal protein 6 homolog, C-terminal coiled coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 2.7 0.00049 0.96 15 54 .. 598 637 .. 591 639 .. 0.91 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00049 Sas-6_C_CC 15 ahkklyalEqntQqLqlElnsqrahieqLgaenskLReaL 54 ++k + E + Lq El+ q+++ ++ + + k+R aL FUN_001867-T1 598 LQKTAELYESDKKELQYELDDQKKRADKEKNDKVKMRHAL 637 577788899999**************************99 PP >> DUF6212 Family of unknown function (DUF6212) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.68 1.3e+03 51 81 .. 366 396 .. 359 409 .. 0.86 2 ? 7.6 2.7 0.0011 2.2 3 72 .. 533 600 .. 531 607 .. 0.94 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.68 DUF6212 51 rraaqlmrelaaLRrehealqeafaaledfl 81 r a++ +++l LR+ +e l+e+ +e+ + FUN_001867-T1 366 REAGNINASLMTLRTCMEMLRENQGSIENGM 396 67889999**************999998755 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0011 DUF6212 3 aalarlldwwsarggleappvlrlddgaaaaaaallvalllaelarlarraaqlmrelaaLRrehealqe 72 ++ ++l+d +s+r g +l+l+++++ a+ ++a l + + r++++l+r l aL +++e lq+ FUN_001867-T1 533 RRRQTLIDDLSRREGIFRAHLLELEKENSQSAT--VIASLKSTIEEKDRDIQKLERRLKALTQKNEMLQK 600 567899**************************9..*******************************9997 PP >> Sec10_N Exocyst complex component Sec10, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 6.5 2.4e-05 0.047 15 95 .. 525 604 .. 518 607 .. 0.89 2 ? -1.5 0.6 1.8 3.5e+03 27 61 .. 650 684 .. 634 701 .. 0.60 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 2.4e-05 Sec10_N 15 LkeLqeqvqekeqklekavrqaeakhskklneLskkldqivdsfqqLdekisevgqkvvelGekLekvdkqRsraleaieL 95 L L ++ q+++q+l +++++ e ++ l+eL+k++ q+ ++L ++i+e +++ +l ++L+ ++++ + ++++eL FUN_001867-T1 525 LHFL-QERQRRRQTLIDDLSRREGIFRAHLLELEKENSQSATVIASLKSTIEEKDRDIQKLERRLKALTQKNEMLQKTAEL 604 4444.4558899***********************************************************9999999998 PP == domain 2 score: -1.5 bits; conditional E-value: 1.8 Sec10_N 27 qklekavrqaeakhskklneLskkldqivdsfqqL 61 ++ +k v+++e + + k+ + ++kl q+ + q++ FUN_001867-T1 650 RECSKRVKDKEIEMQAKMWQKDEKLRQLKEIVQNM 684 55556666666666666555555555444444433 PP >> XLF_CC XLF protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.5 0.19 3.8e+02 13 31 .. 524 542 .. 521 546 .. 0.89 2 ? 9.6 0.8 0.00059 1.2 22 44 .. 565 587 .. 556 592 .. 0.80 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.19 XLF_CC 13 LlqasaalqrqvesLielL 31 Ll++ +++qr+ + Li+ L FUN_001867-T1 524 LLHFLQERQRRRQTLIDDL 542 89999***********977 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00059 XLF_CC 22 rqvesLielLkeKDavIgKLlDk 44 + ++sL ++++eKD+ I+KL + FUN_001867-T1 565 TVIASLKSTIEEKDRDIQKLERR 587 5689*************998555 PP >> DASH_Dad4 DASH complex subunit Dad4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 6 1.2e+04 22 40 .. 370 388 .. 367 393 .. 0.75 2 ? 12.9 0.8 5.9e-05 0.12 18 68 .. 572 622 .. 559 624 .. 0.87 3 ? -2.5 0.1 3.9 7.7e+03 42 53 .. 659 670 .. 655 689 .. 0.64 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 6 DASH_Dad4 22 kLnesvvelnkeleeinkk 40 ++n s+++l +++e ++ FUN_001867-T1 370 NINASLMTLRTCMEMLREN 388 6799999999999876554 PP == domain 2 score: 12.9 bits; conditional E-value: 5.9e-05 DASH_Dad4 18 knvekLnesvvelnkeleeinkkNknvelvsqlwenYqknvqfnLeatgel 68 +++e +++l+++l+ ++kN+ ++ +++l e+ +k++q++L++++++ FUN_001867-T1 572 STIEEKDRDIQKLERRLKALTQKNEMLQKTAELYESDKKELQYELDDQKKR 622 5667777889************************************99875 PP == domain 3 score: -2.5 bits; conditional E-value: 3.9 DASH_Dad4 42 knvelvsqlwen 53 k++e+ +++w++ FUN_001867-T1 659 KEIEMQAKMWQK 670 566666677665 PP >> MIF4G_like_2 MIF4G like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 12.6 0.0021 4.2 143 262 .. 557 688 .. 546 689 .. 0.59 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0021 MIF4G_like_2 143 kneeltratvwEllkrtlskvnkrvkkvrqkleelkekreek.........keeeeeleraeetleaeqaeqkelf.......livferlveilse 222 ++e+ + atv+ +lk+t+++ + ++k++++l++l++k+e+ + +++l+ e ++qk+ + ++l ++s+ FUN_001867-T1 557 EKENSQSATVIASLKSTIEEKDRDIQKLERRLKALTQKNEMLqktaelyesD---------KKELQYELDDQKKRAdkekndkVKMRHALKGVVSQ 643 66778899******************************99996666666441.........44444444433332200000002333333333333 PP MIF4G_like_2 223 s....leeletsgkeegtsvie....ewkrwwierwlrvflrkyakee 262 e+ ++ k+++ e w++ + r l++++++++++e FUN_001867-T1 644 EkgkwERECSKRVKDKEI---EmqakMWQKDEKLRQLKEIVQNMKTNE 688 333234444333332221...134568888888888888888777665 PP >> SlyX SlyX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 4.2 0.0011 2.1 4 55 .. 552 603 .. 549 615 .. 0.86 2 ? 3.9 1.8 0.063 1.2e+02 21 65 .. 662 709 .. 657 709 .. 0.81 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0011 SlyX 4 rleeLEiklafqedtieeLndvvaeqqreidrlqrqlrllaerlkeleesse 55 +l eLE + i +L ++ e++r+i++l+r+l++l+++ + l++++e FUN_001867-T1 552 HLLELEKENSQSATVIASLKSTIEEKDRDIQKLERRLKALTQKNEMLQKTAE 603 577888888888999****************************988887654 PP == domain 2 score: 3.9 bits; conditional E-value: 0.063 SlyX 21 eLndvvaeqqreidrlqrqlrllaerlkeleesseasea...eeepPP 65 e+++ ++++++++ +l++ +++++ k l ++++s+a pPP FUN_001867-T1 662 EMQAKMWQKDEKLRQLKEIVQNMKTNEKPLTRAQAKSAAltrSKSPPP 709 577788999999999999999999999888888887777775666666 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.5 0.2 0.0064 13 22 63 .. 533 574 .. 529 575 .. 0.90 2 ? 12.0 6.1 0.00013 0.25 24 60 .. 577 613 .. 575 617 .. 0.89 3 ? 0.3 2.5 0.57 1.1e+03 38 62 .. 663 687 .. 651 689 .. 0.79 4 ? -2.9 0.0 5.7 1.1e+04 27 39 .. 807 819 .. 806 820 .. 0.67 Alignments for each domain: == domain 1 score: 6.5 bits; conditional E-value: 0.0064 bZIP_1 22 qRKqaeieeLerrvkaLekeNksLkseleelkkevekLkskv 63 +R+q i+ L+rr + + +L +e+++ + +++Lks + FUN_001867-T1 533 RRRQTLIDDLSRREGIFRAHLLELEKENSQSATVIASLKSTI 574 577889*********************************975 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00013 bZIP_1 24 KqaeieeLerrvkaLekeNksLkseleelkkevekLk 60 K i++Lerr kaL+++N++L++++e ++ + ++L+ FUN_001867-T1 577 KDRDIQKLERRLKALTQKNEMLQKTAELYESDKKELQ 613 677899***********************99988886 PP == domain 3 score: 0.3 bits; conditional E-value: 0.57 bZIP_1 38 LekeNksLkseleelkkevekLksk 62 +++++ + ++l +lk+ v+++k++ FUN_001867-T1 663 MQAKMWQKDEKLRQLKEIVQNMKTN 687 55666666789************87 PP == domain 4 score: -2.9 bits; conditional E-value: 5.7 bZIP_1 27 eieeLerrvkaLe 39 e+e L++r+++L+ FUN_001867-T1 807 EVETLKTRSDQLS 819 5677777777775 PP >> TseH Type VI secretion system effector TseH-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 1.8 3.5e+03 145 161 .. 44 60 .. 41 65 .. 0.81 2 ? 3.1 1.5 0.056 1.1e+02 78 125 .. 568 617 .. 557 638 .. 0.74 3 ? 6.5 0.2 0.005 9.8 72 107 .. 655 692 .. 640 706 .. 0.73 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.8 TseH 145 knnnnCsrfvtdvlias 161 +++ +C+++v d++++ FUN_001867-T1 44 NEEESCVQIVSDTILQL 60 57899********9875 PP == domain 2 score: 3.1 bits; conditional E-value: 0.056 TseH 78 iklkaki..engkisnleeilkeleekpekthgegrlvasvleeikykka 125 +lk +i ++ +i+ le lk+l++k+e+ +++ +l+ s +e +y+ FUN_001867-T1 568 ASLKSTIeeKDRDIQKLERRLKALTQKNEMLQKTAELYESDKKELQYELD 617 44555564367788**************************9999888643 PP == domain 3 score: 6.5 bits; conditional E-value: 0.005 TseH 72 tdpeleiklkaki..engkisnleeilkeleekpekth 107 +++ ei+++ak+ +++k++ l+ei+++++++++ FUN_001867-T1 655 RVKDKEIEMQAKMwqKDEKLRQLKEIVQNMKTNEKPLT 692 44555566666666588999************998554 PP >> FUT8_N_cat Alpha-(1,6)-fucosyltransferase N- and catalytic domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 14.5 0.0073 14 35 162 .. 571 698 .. 548 725 .. 0.63 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.0073 FUT8_N_cat 35 aeeeeesskrleevlekleelkkqneelkellekrleeseeekkkaeeklk.sleeklekakekleeak.kskknelsleyEvlrrrleneikElw 128 +++ ee+ ++++++ ++l++l ++ne l++ +e + ++++e + + +++ k + +ek++k k + ++ k +++++ ++e+E +r++++ E+ FUN_001867-T1 571 KSTIEEKDRDIQKLERRLKALTQKNEMLQKTAELYESDKKELQYELDDQKKrADKEKNDKVKMR-HALKgVVSQEKGKWEREC-SKRVKDKEIEMQ 664 23337788999999999************98888443333333323322220233333333322.233324455555666665.456777778888 PP FUT8_N_cat 129 yllsselkklkkeekeeelekeieellellaeqk 162 + ++ +kl++ ++ ++ k+ e+ l+ ++ ++ FUN_001867-T1 665 AKMWQKDEKLRQLKEIVQNMKTNEKPLTRAQAKS 698 8888888888888877766666666665554444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (870 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2244 (0.087845); expected 510.9 (0.02) Passed bias filter: 549 (0.0214915); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 27 (0.00105696); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.46u 0.41s 00:00:00.87 Elapsed: 00:00:00.43 # Mc/sec: 8135.05 // Query: FUN_001868-T1 [L=125] Description: FUN_001868 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 2.5 8.5 7.0 18 5.7 0.4 2.6 2 Zn_ribbon_TEX13 Putative testis-expressed protein 13C, zinc Domain annotation for each model (and alignments): >> Zn_ribbon_TEX13 Putative testis-expressed protein 13C, zinc finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.4 0.00072 18 12 19 .. 63 70 .. 62 71 .. 0.93 2 ? 5.4 1.2 0.00092 24 12 20 .] 117 125 .] 116 125 .] 0.86 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.00072 Zn_ribbon_TEX13 12 PRnKvCyK 19 PR KvC K FUN_001868-T1 63 PRTKVCLK 70 9*****88 PP == domain 2 score: 5.4 bits; conditional E-value: 0.00092 Zn_ribbon_TEX13 12 PRnKvCyKC 20 P K CyKC FUN_001868-T1 117 PGSKWCYKC 125 56799**** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (125 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 613 (0.0239969); expected 510.9 (0.02) Passed bias filter: 467 (0.0182815); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1286.32 // Query: FUN_001869-T1 [L=244] Description: FUN_001869 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (244 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2353 (0.092112); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 113 (0.00442357); expected 25.5 (0.001) Passed Fwd filter: 60 (0.0023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.52u 0.41s 00:00:00.93 Elapsed: 00:00:00.42 # Mc/sec: 2329.53 // Query: FUN_001870-T1 [L=99] Description: FUN_001870 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 701 (0.0274418); expected 510.9 (0.02) Passed bias filter: 494 (0.0193384); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1002.33 // Query: FUN_001871-T1 [L=455] Description: FUN_001871 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.05 14.2 0.1 0.32 11.6 0.0 2.1 2 Type_III_YscG Bacterial type III secretion system chaperone Domain annotation for each model (and alignments): >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.069 1.8e+03 14 34 .. 173 193 .. 168 200 .. 0.79 2 ? 11.6 0.0 1.3e-05 0.32 8 38 .. 203 233 .. 197 248 .. 0.85 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.069 Type_III_YscG 14 lvGsGqhcheeaniiaewler 34 l+ G+h +ea i+ l FUN_001871-T1 173 LITNGNHTGNEAYYISCDLIA 193 8999********999765554 PP == domain 2 score: 11.6 bits; conditional E-value: 1.3e-05 Type_III_YscG 8 llaeialvGsGqhcheeaniiaewlerkgee 38 a + l+ sG+h +ean+i+ l +g++ FUN_001871-T1 203 NYASLDLITSGNHTGNEANCISPDLIANGNQ 233 578999***************9887776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (455 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 525 (0.020552); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4396.82 // Query: FUN_001872-T1 [L=91] Description: FUN_001872 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00032 21.2 5.6 0.00058 20.3 5.6 1.4 1 PHD PHD-finger 0.0025 18.2 2.6 0.0042 17.5 2.6 1.4 1 PHD_4 PHD-finger 0.0028 18.2 1.1 0.0036 17.8 1.1 1.2 1 PHD_5 PhD finger domain 0.0099 16.7 2.0 0.24 12.2 0.3 2.2 2 C1_2 C1 domain ------ inclusion threshold ------ 0.012 16.3 2.9 0.017 15.8 2.9 1.2 1 zf-HC5HC2H PHD-like zinc-binding domain 0.051 13.9 6.5 0.11 12.8 1.2 2.1 2 C1_1 Phorbol esters/diacylglycerol binding domain (C1 0.056 13.8 2.7 9.9 6.6 0.0 2.2 2 DUF7836 Domain of unknown function (DUF7836) 1.6 9.5 7.0 3.3 8.5 0.8 2.3 2 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding Domain annotation for each model (and alignments): >> PHD PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 5.6 1.8e-07 0.00058 10 47 .] 42 80 .. 38 80 .. 0.80 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1.8e-07 PHD 10 deelvlCdgCkkwfHlkClkppleke.elpegewlCpeC 47 +++ C +Ck wfH++C ++ +++ ++p+++ +C+ C FUN_001872-T1 42 NGFYFECTECKIWFHPECQNMAQKDIsDDPQESTYCTAC 80 678899**************9988540444448899999 PP >> PHD_4 PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 2.6 1.3e-06 0.0042 27 64 .. 45 80 .. 39 83 .. 0.88 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1.3e-06 PHD_4 27 lleCsiCyeivHpeClkekngegvvnddlpnsWeCpkC 64 + eC+ C HpeC ++ ++ ++dd +s C C FUN_001872-T1 45 YFECTECKIWFHPECQNM--AQKDISDDPQESTYCTAC 80 78****************..667789999999999999 PP >> PHD_5 PhD finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 1.1 1.1e-06 0.0036 19 46 .. 41 68 .. 39 82 .. 0.83 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 1.1e-06 PHD_5 19 enGfmiqceeclcwqhsvcmGlleesip 46 enGf +c ec w h c + ++ i FUN_001872-T1 41 ENGFYFECTECKIWFHPECQNMAQKDIS 68 9******************998887775 PP >> C1_2 C1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.3 7.5e-05 0.24 26 47 .. 40 59 .. 38 60 .. 0.88 2 ? 4.0 0.1 0.028 89 13 26 .. 70 83 .. 63 89 .. 0.79 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 7.5e-05 C1_2 26 kidgfesfYsCseCdfvlHerC 47 + +gf+ ++C+eC+ +H +C FUN_001872-T1 40 PENGFY--FECTECKIWFHPEC 59 567899..************** PP == domain 2 score: 4.0 bits; conditional E-value: 0.028 C1_2 13 prdesktCdaCgkk 26 + +es C aC+ + FUN_001872-T1 70 DPQESTYCTACQAQ 83 6688999****876 PP >> zf-HC5HC2H PHD-like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.8 2.9 5.2e-06 0.017 48 88 .. 43 81 .. 40 84 .. 0.86 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 5.2e-06 zf-HC5HC2H 48 GaciqCskkkCkrafHvtCaleaglllefeeeeekfksfCk 88 G ++C++ Ck +fH+ C a+ ++ + +e+++ + C+ FUN_001872-T1 43 GFYFECTE--CKIWFHPECQNMAQKDISDDPQESTYCTACQ 81 88899999..*************999999988888888886 PP >> C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 1.2 3.4e-05 0.11 29 48 .. 46 65 .. 41 70 .. 0.87 2 ? 4.5 0.3 0.014 44 10 21 .. 73 84 .. 67 90 .. 0.76 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3.4e-05 C1_1 29 lkCswCklnvHkkClekvpp 48 + C++Ck+ +H +C++ +++ FUN_001872-T1 46 FECTECKIWFHPECQNMAQK 65 78************998876 PP == domain 2 score: 4.5 bits; conditional E-value: 0.014 C1_1 10 qptfCdhCgell 21 ++t+C C+ + FUN_001872-T1 73 ESTYCTACQAQQ 84 789999999765 PP >> DUF7836 Domain of unknown function (DUF7836) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.0031 9.9 21 37 .. 36 52 .. 33 54 .. 0.88 2 ? 6.3 1.6 0.0039 13 11 39 .. 57 83 .. 55 85 .. 0.83 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0031 DUF7836 21 psdLpapdenFsCpnCh 37 p Lp+++ F+C++C+ FUN_001872-T1 36 PVGLPENGFYFECTECK 52 6789************7 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0039 DUF7836 11 peCkkewesspsdLpapdenFsCpnChat 39 peC++ ++++sd p++ + C+ C+a+ FUN_001872-T1 57 PECQNMAQKDISDDPQE--STYCTACQAQ 83 9***********97665..456****997 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.8 0.001 3.3 2 12 .. 46 56 .. 45 58 .. 0.92 2 ? 4.3 0.7 0.021 67 3 9 .. 76 82 .. 76 83 .. 0.87 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.001 zf-C2H2_jaz 2 fYCvlCdKyFk 12 f+C++C+ +F+ FUN_001872-T1 46 FECTECKIWFH 56 99********6 PP == domain 2 score: 4.3 bits; conditional E-value: 0.021 zf-C2H2_jaz 3 YCvlCdK 9 YC++C+ FUN_001872-T1 76 YCTACQA 82 9****96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (91 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 794 (0.0310824); expected 510.9 (0.02) Passed bias filter: 420 (0.0164416); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 937.82 // Query: FUN_001873-T1 [L=141] Description: FUN_001873 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (141 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 357 (0.0139753); expected 510.9 (0.02) Passed bias filter: 326 (0.0127618); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1420.25 // Query: FUN_001874-T1 [L=116] Description: FUN_001874 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 575 (0.0225093); expected 510.9 (0.02) Passed bias filter: 498 (0.019495); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1179.07 // Query: FUN_001875-T1 [L=185] Description: FUN_001875 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-05 22.9 0.0 0.00012 22.4 0.0 1.2 1 DEAD DEAD/DEAH box helicase ------ inclusion threshold ------ 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 DUF4817 Helix-turn-helix domain (DUF4817) 4.7 8.0 7.0 0.8 10.4 1.5 2.1 2 C5HCH NSD Cys-His rich domain Domain annotation for each model (and alignments): >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.0 1.4e-08 0.00012 2 33 .. 27 58 .. 26 73 .. 0.87 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.4e-08 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF DEAD 2 piQaeaipallegkdvlvqapTGsGKTlafll 33 p Q++a+ ++l g++++v pTG+GK+l+f+ FUN_001875-T1 27 PEQENALREFLGGQNIFVNLPTGYGKSLIFQC 58 67***************************975 PP >> DUF4817 Helix-turn-helix domain (DUF4817) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 3.7e-05 0.32 15 40 .. 5 30 .. 4 33 .. 0.92 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 3.7e-05 DUF4817 15 sqksvkqtqrafreqFpnrrlPsrst 40 ++++ ++++ a reqF++++lP++++ FUN_001875-T1 5 TEECWQKAFKAVREQFEIDNLPPEQE 30 67899******************985 PP >> C5HCH NSD Cys-His rich domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 1.5 9.4e-05 0.8 1 27 [. 74 99 .. 74 102 .. 0.89 2 ? -0.0 0.3 0.17 1.5e+03 5 18 .. 144 157 .. 142 161 .. 0.80 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 9.4e-05 C5HCH 1 WHqCseCgkaatsfCeFCPssFCkdHe 27 W qCs C+ a++ + P s Ck+H FUN_001875-T1 74 WFQCSRCHI-AVAIADGRPDSACKQHG 99 *******75.788999**********6 PP == domain 2 score: -0.0 bits; conditional E-value: 0.17 C5HCH 5 seCgkaatsfCeFC 18 s+C+ + +f +FC FUN_001875-T1 144 SVCSISDRRFFQFC 157 68888888888898 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (185 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 665 (0.0260325); expected 510.9 (0.02) Passed bias filter: 572 (0.0223919); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1837.14 // Query: FUN_001876-T1 [L=235] Description: FUN_001876 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (235 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2066 (0.0808769); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 105 (0.00411039); expected 25.5 (0.001) Passed Fwd filter: 58 (0.0022705); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.52u 0.39s 00:00:00.91 Elapsed: 00:00:00.41 # Mc/sec: 2285.15 // Query: FUN_001877-T1 [L=610] Description: FUN_001877 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00043 20.8 0.9 0.65 10.6 0.0 3.2 3 Type_III_YscG Bacterial type III secretion system chaperone Domain annotation for each model (and alignments): >> Type_III_YscG Bacterial type III secretion system chaperone protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.018 4.7e+02 14 29 .. 224 239 .. 219 242 .. 0.88 2 ! 5.9 0.3 0.0007 18 14 30 .. 242 258 .. 230 271 .. 0.81 3 ! 10.6 0.0 2.5e-05 0.65 8 38 .. 272 302 .. 265 311 .. 0.82 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.018 Type_III_YscG 14 lvGsGqhcheeaniia 29 l+ G+h +ea +i+ FUN_001877-T1 224 LITNGNHTGNEAYCIS 239 8999**********97 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0007 Type_III_YscG 14 lvGsGqhcheeaniiae 30 l+ sG+h +ean+i+ FUN_001877-T1 242 LITSGNHTGNEANCISC 258 899************74 PP == domain 3 score: 10.6 bits; conditional E-value: 2.5e-05 Type_III_YscG 8 llaeialvGsGqhcheeaniiaewlerkgee 38 a + l+ sG+h +ean+i+ l +g++ FUN_001877-T1 272 NYASLDLITSGNHTGKEANCISPDLIANGNQ 302 57999****************9887776654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (610 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 613 (0.0239969); expected 510.9 (0.02) Passed bias filter: 479 (0.0187512); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5867.95 // Query: FUN_001878-T1 [L=428] Description: FUN_001878 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-45 156.3 0.0 2.3e-45 155.7 0.0 1.2 1 DZF_N DZF N-terminal domain 1.5e-37 129.2 0.0 2.5e-37 128.5 0.0 1.4 1 DZF_C DZF C-terminal domain ------ inclusion threshold ------ 0.18 12.5 0.0 0.29 11.8 0.0 1.3 1 SMODS Second Messenger Oligonucleotide or Dinucleotide Sy Domain annotation for each model (and alignments): >> DZF_N DZF N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 155.7 0.0 2.7e-49 2.3e-45 3 209 .. 37 241 .. 35 242 .. 0.92 Alignments for each domain: == domain 1 score: 155.7 bits; conditional E-value: 2.7e-49 DZF_N 3 RvaPfm...nkktF.vprhifdltlae...pkvesakdDsvltkallkraqdltPtaeeqkaiqnlvskveaaLkkekaenlvvapgdltkcleev 91 R++P+m ++F v fd lae p+ +a d+ ++t+allkr+q+ltP+ +eq +qnlv+kv ++L +nl+v p+ +eev FUN_001878-T1 37 RMPPYMrgpPGQKFvVSHSTFDPILAEnffPRTVPASDEIAFTQALLKRNQELTPSGQEQASVQNLVTKVTTVL-----DNLIVTPEAADLGVEEV 127 78899977645677577899*******9**********************************************.....********77777**** PP DZF_N 92 rrvGsfkkgtllkgsnkadvvvllktlPtkeaveaLgkkveenlkislktevvdkgealqlvdekgieiknt.sakvrlliavlpeelrklepekh 186 r vGsfkkgt+l g +ad+ v+lk+lPt+ + L+ kv++ l+ + + ++q+ +e g++i++ a vr+lia+lp++l +p +h FUN_001878-T1 128 RAVGSFKKGTMLLGHPVADLAVILKNLPTETIILTLATKVQKSLQEEGS----VTEYPMQS-NEGGFNISSPdGALVRVLIATLPKNLCEADPAQH 218 *****************************9999*******988875543....34567777.8*******985799******************** PP DZF_N 187 LDskkilsalasiRHtkWFeena 209 +D k + ala+iRH++WFeena FUN_001878-T1 219 VDVKLLEGALATIRHARWFEENA 241 *********************98 PP >> DZF_C DZF C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 128.5 0.0 2.9e-41 2.5e-37 2 132 .. 246 380 .. 245 381 .. 0.91 Alignments for each domain: == domain 1 score: 128.5 bits; conditional E-value: 2.9e-41 DZF_C 2 ikvlirvlkdlarrfdafkPlsaWildllaekaiannPsrqalpvgealrrvlellaaGlflPdsagiidPvevgh.rvhtdltleqqdevcmtaq 96 +++l+r++kdl++rf +f+ l++W +dlla++a + srq lpv++a+rr ++ll++GlflP+s giidP+e g r h l le qd +++ aq FUN_001878-T1 246 TRLLVRLFKDLRKRFTGFQGLTPWLIDLLAHRAAMASSSRQPLPVNIAFRRAFQLLSSGLFLPGSLGIIDPCESGNvRAHSVLSLEEQDAIATCAQ 341 5789*********************************************************************9999******************* PP DZF_C 97 tllrvlatGgykkil..Glegnas.dlakeisvwngvei 132 tllr l +G +++il G eg + l e+ w gv + FUN_001878-T1 342 TLLRCLNHGAFNEILslGQEGIPQvALDTEVTSWGGVIV 380 **************7225555553146678888888866 PP >> SMODS Second Messenger Oligonucleotide or Dinucleotide Synthetase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 3.4e-05 0.29 5 64 .. 80 143 .. 77 174 .. 0.76 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 3.4e-05 SMODS 5 sqFkeflsnielsqttkdsissrvkaitkaLnkdf.eles...ktaesllsGSyargTaikpvs 64 + + + +++++s ++++s+++ v ++t+ L++ ++e ++e +GS+++gT + + FUN_001878-T1 80 QALLKRNQELTPSGQEQASVQNLVTKVTTVLDNLIvTPEAadlGVEEVRAVGSFKKGTMLLGHP 143 567788899********************99998766655435799*************96533 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (428 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1130 (0.0442357); expected 510.9 (0.02) Passed bias filter: 766 (0.0299863); expected 510.9 (0.02) Passed Vit filter: 83 (0.00324917); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4123.09 // Query: FUN_001879-T1 [L=703] Description: FUN_001879 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-08 35.9 0.0 0.00015 22.9 0.0 2.9 2 Methyltransf_25 Methyltransferase domain 1.4e-06 29.3 0.0 9.4e-05 23.5 0.0 2.8 2 Methyltransf_11 Methyltransferase domain 9.8e-06 25.9 0.7 4.1e-05 23.9 0.0 2.3 3 Methyltransf_31 Methyltransferase domain 0.00039 20.3 0.1 0.0013 18.7 0.0 1.9 2 Ubie_methyltran ubiE/COQ5 methyltransferase family 0.0052 16.8 0.0 0.015 15.4 0.0 1.7 1 Spermine_synth Spermine/spermidine synthase domain ------ inclusion threshold ------ 0.033 15.4 0.0 1.7 9.9 0.0 2.6 2 Methyltransf_12 Methyltransferase domain 0.07 14.0 0.4 5.5 7.9 0.1 2.5 2 SCP2 SCP-2 sterol transfer family Domain annotation for each model (and alignments): >> Methyltransf_25 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.0 4.1e-08 0.00015 14 97 .] 120 213 .. 115 213 .. 0.73 2 ! 9.7 0.0 0.00053 2 4 90 .. 543 632 .. 541 634 .. 0.75 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 4.1e-08 Methyltransf_25 14 elakrlgeaevtgvDlseemlerareraaeeglnvefvqgdaed..lpfedgsfdlvvssgalhhlsde.........dleaalaeiarvLkpg 96 l ++ g + v+gv+ e+ + +re+++++ ++++fv+g++++ l+fe++sf +v+ g+l l+++ d+ ++l+ + r+Lk g FUN_001879-T1 120 DLYDA-GYQCVVGVETTENNICNLREKNKDKRPEMKFVEGKLQElkLSFEQESFSVVIDRGELDALHENvstgkrtdiDVTEYLKAVQRLLKVG 212 56666.5799********************************8833569*********987787655331111111115566666666666666 PP Methyltransf_25 97 G 97 G FUN_001879-T1 213 G 213 6 PP == domain 2 score: 9.7 bits; conditional E-value: 0.00053 Methyltransf_25 4 lGcGtGrlalelakrlgeaevtgvDlseemlerareraaeegl.nvefvqgda.edlpfedgsfdlvvssga.lhhlsdedleaalaeia 90 +G G G la+ l++ +++ ++ v+l+++ ++a++ ++ ++ +++++ +d e++ + + v+ ++ l +dl+a++ e++ FUN_001879-T1 543 VGLGGGGLAMFLHQYFKQLSIEVVELDPSISDIAKSWFQLKEDeRMKVIIQDGlENIRSKGVFILNLVCRNTdLRNQVVDDLRAVFPELY 632 9***************98999999999999999999997755569999888874556655544444555566677766677777777766 PP >> Methyltransf_11 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 2.6e-08 9.4e-05 13 95 .] 120 217 .. 114 217 .. 0.83 2 ? 2.8 0.0 0.074 2.7e+02 3 43 .. 543 587 .. 541 607 .. 0.71 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 2.6e-08 Methyltransf_11 13 alarlg.arvtgvDlspemlelakekakkegl.vefvqadaed..lpfpdesfDlvlssevlhhve...........dpekalreiaRvLkpgG 91 l ++g v+gv+++++ + + +ek+k+++ ++fv++ +++ l f+ esf +v+ + l ++ d+ ++l+ + R+Lk gG FUN_001879-T1 120 DLYDAGyQCVVGVETTENNICNLREKNKDKRPeMKFVEGKLQElkLSFEQESFSVVIDRGELDALHenvstgkrtdiDVTEYLKAVQRLLKVGG 213 5666666779**********9999999999999*********83357************977777334556666667***************** PP Methyltransf_11 92 llvi 95 ++++ FUN_001879-T1 214 RFLC 217 *986 PP == domain 2 score: 2.8 bits; conditional E-value: 0.074 Methyltransf_11 3 vGcGtGllaealarlg....arvtgvDlspemlelakekakkegl 43 vG G+G la l +++ +v+ +D+s +++++ ++k+++ FUN_001879-T1 543 VGLGGGGLAMFLHQYFkqlsIEVVELDPSISDIAKSWFQLKEDER 587 899999999999988888567777777777666666555555544 PP >> Methyltransf_31 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 1.1e-08 4.1e-05 31 113 .. 129 221 .. 113 232 .. 0.84 2 ? -3.0 0.0 2.1 7.6e+03 50 84 .. 288 331 .. 266 358 .. 0.50 3 ? -1.4 0.0 0.7 2.6e+03 93 127 .. 591 625 .. 558 645 .. 0.72 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 1.1e-08 Methyltransf_31 31 vvGiDiseeaiekArenaeklglknvkFeqgdieelpesledekfDviisnevl...........navpdpdkvleeiervlkpggillisdid 113 vvG++ +e+ i + re+ +++ ++kF +g +el+ s+e+e+f v+i+++ l + d ++l+ ++r+lk gg++l ++ FUN_001879-T1 129 VVGVETTENNICNLREKNKDKRP-EMKFVEGKLQELKLSFEQESFSVVIDRGELdalhenvstgkRTDIDVTEYLKAVQRLLKVGGRFLCFTFA 221 9***************9999999.5************77************9996667777777777777777888************976655 PP == domain 2 score: -3.0 bits; conditional E-value: 2.1 Methyltransf_31 50 klglknvkFeqgdiee.lpes..led......ekfDviisnevl 84 + +++vk ++++i++ + ++ le+ k+D+ i++ FUN_001879-T1 288 LRSFSDVKTILQEIQQyFVMKksLERccagvhHKVDLHITSASP 331 44555555555555554332211222444444555554444444 PP == domain 3 score: -1.4 bits; conditional E-value: 0.7 Methyltransf_31 93 vleeiervlkpggillisdidalaelpaevkeese 127 +++ ++ +++g+++++ ++ ++l +v ++ + FUN_001879-T1 591 IIQDGLENIRSKGVFILNLVCRNTDLRNQVVDDLR 625 45555567788888888888888888888777766 PP >> Ubie_methyltran ubiE/COQ5 methyltransferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 3.4e-07 0.0013 99 167 .. 152 233 .. 112 249 .. 0.71 2 ? -4.0 0.0 2.9 1.1e+04 126 141 .. 288 303 .. 288 315 .. 0.74 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 3.4e-07 Ubie_methyltran 99 nieflqanaee..LpfeddsfDvv...........tisfGlrnvtDklkaLkeifrvlkpGGrlvvlefskvelpllsqaye 167 +++f++++ +e L fe++sf vv +s G r D ++ Lk + r lk+GGr++++ f+ ve+ + y+ FUN_001879-T1 152 EMKFVEGKLQElkLSFEQESFSVVidrgeldalheNVSTGKRTDIDVTEYLKAVQRLLKVGGRFLCFTFATVEILNYLLDYF 233 556666654431145666666554233222222335999*********************************9988877775 PP == domain 2 score: -4.0 bits; conditional E-value: 2.9 Ubie_methyltran 126 lrnvtDklkaLkeifr 141 lr ++D ++ L+ei + FUN_001879-T1 288 LRSFSDVKTILQEIQQ 303 6899999999998743 PP >> Spermine_synth Spermine/spermidine synthase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 4e-06 0.015 18 86 .. 536 600 .. 526 607 .. 0.87 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 4e-06 Spermine_synth 18 npkkVLiiGGgDGgvlrevvkhksvekitlvdiDekvidvskkflpklaigfddervklviedgfkflk 86 + k+ Li+G g Gg++ + ++ +i +v++D ++ d+ k+ ++ ++der+k++i+dg + ++ FUN_001879-T1 536 EVKRSLIVGLGGGGLAMFLHQYFKQLSIEVVELDPSISDIAKSWFQL----KEDERMKVIIQDGLENIR 600 678889***99999999999999899******************974....4789*********98765 PP >> Methyltransf_12 Methyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00047 1.7 23 98 .] 129 215 .. 115 215 .. 0.77 2 ? 2.7 0.0 0.084 3.1e+02 1 41 [. 541 581 .. 541 626 .. 0.79 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00047 Methyltransf_12 23 yvgvDispaaleaarerlaalerldaarveleqldlaeeepe....sfDvvvasnvlhhl...........adleevlrnlrrlLkpgGvl 98 +vgv+ +++ + + re+ +++++ ++ve + ++l sf vv+ + l +l d++e l+ ++rlLk gG++ FUN_001879-T1 129 VVGVETTENNICNLREKNKDKRP-EMKFVEGKLQELKL---SfeqeSFSVVIDRGELDALhenvstgkrtdIDVTEYLKAVQRLLKVGGRF 215 67999999999777777777776.44444444444333...23347*********99999999*****9888899**************86 PP == domain 2 score: 2.7 bits; conditional E-value: 0.084 Methyltransf_12 1 LeiGcGtGallrallealpgleyvgvDispaaleaarerla 41 L +G G G l+ +l +++++l++ +v+++p+ + a+ ++ FUN_001879-T1 541 LIVGLGGGGLAMFLHQYFKQLSIEVVELDPSISDIAKSWFQ 581 56899*************88888888888887766665444 PP >> SCP2 SCP-2 sterol transfer family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.9 0.1 0.0015 5.5 7 47 .. 142 188 .. 137 210 .. 0.78 2 ? 3.7 0.0 0.029 1.1e+02 21 72 .. 630 683 .. 607 687 .. 0.81 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0015 SCP2 7 r..kdpeakealkklagkvlqfdlkdlklsltldlkegkgsv....l 47 + k++++++++k ++gk +++l+ +++s+ ++++ g++++ + FUN_001879-T1 142 LreKNKDKRPEMKFVEGKLQELKLSFEQESFSVVIDRGELDAlhenV 188 333467*********************99************965543 PP == domain 2 score: 3.7 bits; conditional E-value: 0.029 SCP2 21 gkvlqfdlkdlklsltldlkegkgsv...laedegkadvtlsasdedllklatgk 72 + + ++++++ +++++ l + +++ ++ ++++ ++++++ +dl ++a+g+ FUN_001879-T1 630 E-LYSIKIEEEVNEIVFALPHLRFQTaleDTKFQESPYTVFQTKVKDLQQIAKGQ 683 3.89999*999999999999999998977677779******************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (703 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 855 (0.0334703); expected 510.9 (0.02) Passed bias filter: 638 (0.0249755); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.40u 0.36s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 6881.29 // Query: FUN_001880-T1 [L=105] Description: FUN_001880 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (105 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 307 (0.012018); expected 510.9 (0.02) Passed bias filter: 269 (0.0105304); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1058.25 // Query: FUN_001881-T1 [L=1159] Description: FUN_001881 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-77 256.4 29.1 4.9e-13 49.6 0.0 10.5 10 TPR_12 Tetratricopeptide repeat 2.3e-59 201.7 0.0 3.7e-59 201.0 0.0 1.3 1 CHAT CHAT domain 4.9e-49 162.7 36.2 1.7e-07 31.2 0.0 15.0 15 TPR_1 Tetratricopeptide repeat 2.4e-46 152.5 36.5 9.6e-06 25.8 0.0 15.4 15 TPR_2 Tetratricopeptide repeat 1.7e-38 130.0 31.8 0.00099 19.5 0.0 16.3 17 TPR_10 Tetratricopeptide repeat 7.1e-35 116.6 26.6 0.0033 17.9 0.0 14.3 14 TPR_7 Tetratricopeptide repeat 8.9e-31 103.9 34.8 1e-05 25.8 0.1 15.2 15 TPR_8 Tetratricopeptide repeat 1.1e-21 75.5 16.0 0.055 14.7 0.0 14.3 14 TPR_14 Tetratricopeptide repeat 5.9e-21 75.4 2.7 0.00027 20.9 0.0 5.1 4 TPR_NPHP3 Nephrocystin-3 TPR domain 3.6e-18 66.4 4.9 4.7e-08 33.2 0.3 3.7 3 TPR_MalT MalT-like TPR region 6.5e-12 46.0 10.8 0.0015 18.6 1.7 5.5 6 SNAP Soluble NSF attachment protein, SNAP 3.4e-11 43.1 5.3 0.84 9.9 0.1 9.3 10 TPR_11 TPR repeat 3.2e-09 37.2 18.2 0.16 12.2 0.2 7.2 7 RPN7 26S proteasome subunit RPN7 3.8e-09 37.3 2.1 0.026 15.5 0.1 6.2 4 TPR_16 Tetratricopeptide repeat 2.8e-07 31.1 5.4 2 8.8 0.1 6.9 8 ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat 3.3e-07 31.2 12.7 0.2 12.4 0.1 6.7 8 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM 5.1e-07 30.4 22.4 0.16 12.8 0.0 9.7 10 TPR_19 Tetratricopeptide repeat 8.7e-07 29.4 0.0 9.1 6.6 0.0 6.3 5 TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR dom 4.8e-06 27.3 5.1 0.67 11.2 0.0 7.1 4 TPR_6 Tetratricopeptide repeat 1.9e-05 25.1 8.9 21 6.2 0.0 10.0 9 TPR_17 Tetratricopeptide repeat 2.3e-05 24.8 1.6 25 5.5 0.0 5.6 4 TPR_9 Tetratricopeptide repeat 5.2e-05 24.0 0.8 0.98 10.2 0.1 4.6 3 TPR_5 Tetratrico peptide repeat 0.00018 22.3 0.4 1.3e+02 4.1 0.0 7.7 7 TPR_4 Tetratricopeptide repeat 0.00021 20.9 2.4 5.8 6.3 0.1 5.2 5 Paf67 RNA polymerase I-associated factor PAF67 0.00023 22.1 9.1 3.9 8.7 0.0 6.9 5 Sel1 Sel1 repeat 0.006 16.5 4.2 0.061 13.2 0.1 3.8 4 Coatomer_E Coatomer epsilon subunit 0.0064 17.0 1.0 3.6 8.2 0.0 5.4 5 ANAPC5 Anaphase-promoting complex subunit 5 0.0091 16.5 0.1 44 4.5 0.0 4.0 4 Wzy_C_2 Virulence factor membrane-bound polymerase, C- ------ inclusion threshold ------ 0.015 15.6 3.0 14 6.0 0.0 5.3 6 DUF7380 Domain of unknown function (DUF7380) 0.021 15.5 26.9 66 4.6 0.1 12.1 12 PPR PPR repeat 0.029 14.8 15.6 1.1 9.7 0.2 6.4 6 DUF3856 Domain of Unknown Function (DUF3856) 0.058 13.6 1.9 16 5.6 0.1 4.6 4 TPR_21 Tetratricopeptide repeat-like domain 0.097 12.6 4.1 10 6.0 0.0 4.4 3 TPR_15 Tetratricopeptide repeat 0.11 12.7 8.1 17 5.6 0.5 4.9 5 TPR_COPA_B COPA/B TPR domain 0.11 12.8 9.0 7.2 6.9 0.2 6.8 7 HEAT_Nup120 Nucleoporin Nup120, HEAT repeats 0.23 12.3 23.0 4 8.3 0.1 7.7 6 ANAPC3 Anaphase-promoting complex, cyclosome, subunit 0.43 11.4 9.1 4.4 8.1 0.0 5.2 4 NRBF2_MIT MIT domain of nuclear receptor-binding factor Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.048 33 52 72 .. 18 38 .. 15 43 .. 0.61 2 ? 6.4 0.1 0.022 15 11 41 .. 66 96 .. 56 102 .. 0.78 3 ! 26.9 0.1 8.2e-09 5.7e-06 18 76 .. 138 194 .. 133 195 .. 0.94 4 ! 27.3 0.2 6.2e-09 4.3e-06 3 56 .. 203 254 .. 201 256 .. 0.90 5 ! 46.9 0.1 4.6e-15 3.2e-12 6 75 .. 246 313 .. 240 315 .. 0.92 6 ! 49.6 0.0 7.1e-16 4.9e-13 6 74 .. 326 392 .. 322 393 .. 0.95 7 ! 14.8 0.2 5e-05 0.035 6 37 .. 406 437 .. 401 449 .. 0.84 8 ! 29.1 0.8 1.7e-09 1.2e-06 6 77 .] 451 520 .. 445 520 .. 0.95 9 ! 37.7 0.0 3.7e-12 2.5e-09 15 77 .] 540 600 .. 530 600 .. 0.92 10 ! 33.4 0.0 7.8e-11 5.4e-08 5 74 .. 610 677 .. 607 680 .. 0.94 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.048 TPR_12 52 grlylalgdyeeAlelleqal 72 + ++l+ +y +A+el++++l FUN_001881-T1 18 ASVLLQIRRYGKAIELFNECL 38 556666667777777777666 PP == domain 2 score: 6.4 bits; conditional E-value: 0.022 TPR_12 11 avlrrlgrydeAlellekalelaerllGpdh 41 ++++ g+++ Al+ eka+++++++++ d FUN_001881-T1 66 SLYCLVGDHARALQSGEKAHAMHSQSGNIDG 96 6799999999999999999999988876665 PP == domain 3 score: 26.9 bits; conditional E-value: 8.2e-09 TPR_12 18 rydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +y +A +++e ale+++++ +++ ++ +l +Lg+l+ al++y+ lle+al i+e FUN_001881-T1 138 NYSQAKDCFEGALEIWKEI--GNRREEGKTLSLLGDLFNALKEYRRSKLLLERALVILE 194 7899***************..8899*****************************97766 PP == domain 4 score: 27.3 bits; conditional E-value: 6.2e-09 TPR_12 3 atalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlyl 56 ++l++l+ v++ lg+y+eA +l+++al++ l ++++++++ +rnL+ ++ FUN_001881-T1 203 GNTLSCLGRVCCILGEYEEAKSLQKRALAISVLL--KERDAEIADYRNLANVHA 254 68999**************************555..88999**********986 PP == domain 5 score: 46.9 bits; conditional E-value: 4.6e-15 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 ++nlA+v++ + + deA +++ kal++++++ +d+ ++a +++ Lg y+ l+++ eA+e+++ a++++ FUN_001881-T1 246 YRNLANVHASMSEVDEAKKCFSKALAICKET--GDKSGEAKTYHVLGGFYRCLNNHNEAIECFRLACALF 313 459*************************999..66779****************************9987 PP == domain 6 score: 49.6 bits; conditional E-value: 7.1e-16 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +++l+a+++ gr+deA++++ekal + +++ +d+ ++ a+ nLg ly algd+ +A e++++al++ FUN_001881-T1 326 YSELGALYCSVGRFDEARQCHEKALVIKKEI--GDKRGEGDAYSNLGSLYMALGDPGKAKECYKRALAV 392 568*************************999..77779*****************************97 PP == domain 7 score: 14.8 bits; conditional E-value: 5e-05 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerll 37 + +lA+v+r lg+yd+A l+ekalel +r+ FUN_001881-T1 406 YGHLANVHRVLGDYDKAYLLHEKALELKNRTN 437 4479**********************998874 PP == domain 8 score: 29.1 bits; conditional E-value: 1.7e-09 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++nl+++++ +g+y +A++++++al ++++ d+ ++ +l nL+ l l lg+ e+ ++ e+a +iae+ FUN_001881-T1 451 YSNLGSLCHCRGEYVKAQKYFKRALCIIQEM--VDRRAEGDILINLASLELSLGEEEKSKQYRERAHQIAEA 520 679*************************887..8899********************************985 PP == domain 9 score: 37.7 bits; conditional E-value: 3.7e-12 TPR_12 15 rlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 g++ A e++ek+l +rl +d+ + ++++ g+++ lgd+ +A+e++++al+i+++ FUN_001881-T1 540 SVGDFSRAMEYHEKVLSSSKRL--GDKRCEGSCYHDTGQCHMSLGDHSKAIEYYQRALAIYQA 600 569999999************9..67779********************************85 PP == domain 10 score: 33.4 bits; conditional E-value: 7.8e-11 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 ++nn++ ++ + +y eA+ +l+kal +ae++ d ++ +t+l L+ l+ +g+ eeA ++l +++i FUN_001881-T1 610 INNNMGTSYLLQWNYREAEGCLNKALSIAEEI--RDLEGKSTVLAHLAALCISRGNNEEAFSHLLSSVKI 677 6899****************************..89999************************9988876 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 201.0 0.0 5.4e-62 3.7e-59 5 291 .] 877 1153 .. 873 1153 .. 0.92 Alignments for each domain: == domain 1 score: 201.0 bits; conditional E-value: 5.4e-62 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx RF CHAT 5 raLyqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsaralsrlrrsaasarrapq.lvvgnpdfdraalls 97 + y+ ++ap++++l q+ +++vivpd L+++Pf al d+++ +yL + + i y+ps++ l +++s+a+ ++++ lvvg+pd + ++++ FUN_001881-T1 877 QLWYKNFIAPVADQL--QGSTEIVIVPDRSLYRVPFGALIDENS-KYLSDTFRIRYVPSLTVLNLIQDSPANYHNEAGaLVVGDPDVGT-VMFQ 966 5568899*******9..**************************7.***************9999999998888888669******9874.4555 PP ..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxx RF CHAT 98 ..klvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr......edglLtaeel 183 + +f++lp +++Ea+++ +ll ++++l+ ++at+ea+++ + ++++++H+a+Hg + r+ ++La++ e lLt++++ FUN_001881-T1 967 gvSKQFPRLPCAKREAEMIGALL---HVQPLTERQATKEAVLKKM-NSATLIHIAAHGDAD-----RGDIALASDRHVtrtpleEHFLLTMADV 1051 114567*****************...679***************9.***************.....******866666999999999******* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 184 aelnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddepr 277 ++++++ a+lVvLs C +++g++ +++g+ g+ara+l +Ga+sv++slw+Vdd+at +Lmk fye l gks++e+L++a+ +++d+ + FUN_001881-T1 1052 SKVQVR-AKLVVLSCCHSGRGHI-KAEGIVGIARAFLASGARSVLVSLWNVDDDATMQLMKWFYESLVCGKSASESLHEAMKLMREDPT----Y 1139 ******.**************99.***************************************************************98....5 PP xxxxxxxxxxxxxx RF CHAT 278 hspyyWAafvliGd 291 ++ + WA f+l+Gd FUN_001881-T1 1140 SEVRQWAPFILVGD 1153 66***********7 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.019 13 10 31 .. 20 41 .. 17 44 .. 0.84 2 ? 3.0 0.0 0.21 1.4e+02 7 30 .. 129 152 .. 125 155 .. 0.78 3 ? 2.0 0.0 0.43 3e+02 2 30 .. 164 192 .. 163 195 .. 0.89 4 ? 4.7 0.0 0.059 41 3 28 .. 205 230 .. 203 233 .. 0.80 5 ! 20.1 0.0 8.3e-07 0.00057 4 31 .. 246 273 .. 245 275 .. 0.94 6 ! 12.6 0.2 0.00019 0.13 1 30 [. 283 312 .. 283 315 .. 0.90 7 ! 18.7 0.0 2.2e-06 0.0015 4 30 .. 326 352 .. 323 355 .. 0.91 8 ! 31.2 0.0 2.5e-10 1.7e-07 2 31 .. 364 393 .. 363 394 .. 0.96 9 ! 17.0 0.6 7.8e-06 0.0054 4 30 .. 406 432 .. 403 434 .. 0.94 10 ! 17.3 0.5 6.1e-06 0.0042 2 29 .. 449 476 .. 448 480 .. 0.92 11 ? 0.0 0.1 1.8 1.2e+03 2 30 .. 489 517 .. 488 520 .. 0.86 12 ? 1.8 0.0 0.5 3.5e+02 14 28 .. 541 555 .. 539 556 .. 0.89 13 ! 26.0 0.1 1.1e-08 7.4e-06 8 31 .. 575 598 .. 569 599 .. 0.91 14 ! 12.2 0.1 0.00026 0.18 5 31 .. 612 638 .. 609 640 .. 0.94 15 ? -0.8 0.0 3.3 2.2e+03 4 21 .. 651 668 .. 649 677 .. 0.85 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.019 TPR_1 10 ayfklgkydeAleyyekALeln 31 ++++ +y +A+e ++++L l FUN_001881-T1 20 VLLQIRRYGKAIELFNECLVLL 41 678899************9875 PP == domain 2 score: 3.0 bits; conditional E-value: 0.21 TPR_1 7 lGnayfklgkydeAleyyekALel 30 +G + + +y +A +++e ALe+ FUN_001881-T1 129 IGTKFKSDFNYSQAKDCFEGALEI 152 5555566669*********99997 PP == domain 3 score: 2.0 bits; conditional E-value: 0.43 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k+l lG ++ +l++y e+AL + FUN_001881-T1 164 KTLSLLGDLFNALKEYRRSKLLLERALVI 192 67899************999999999965 PP == domain 4 score: 4.7 bits; conditional E-value: 0.059 TPR_1 3 alynlGnayfklgkydeAleyyekAL 28 +l lG ++ lg+y+eA ++AL FUN_001881-T1 205 TLSCLGRVCCILGEYEEAKSLQKRAL 230 67889*************86666655 PP == domain 5 score: 20.1 bits; conditional E-value: 8.3e-07 TPR_1 4 lynlGnayfklgkydeAleyyekALeln 31 + nl+n++ ++ + deA ++++kAL ++ FUN_001881-T1 246 YRNLANVHASMSEVDEAKKCFSKALAIC 273 77***********************986 PP == domain 6 score: 12.6 bits; conditional E-value: 0.00019 TPR_1 1 akalynlGnayfklgkydeAleyyekALel 30 ak++ lG y+ l++++eA+e+++ A l FUN_001881-T1 283 AKTYHVLGGFYRCLNNHNEAIECFRLACAL 312 789999999***************998766 PP == domain 7 score: 18.7 bits; conditional E-value: 2.2e-06 TPR_1 4 lynlGnayfklgkydeAleyyekALel 30 + lG++y + g++deA ++ ekAL + FUN_001881-T1 326 YSELGALYCSVGRFDEARQCHEKALVI 352 899**********************77 PP == domain 8 score: 31.2 bits; conditional E-value: 2.5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG +y++lg++ +A e+y++AL ++ FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRALAVD 393 79*************************987 PP == domain 9 score: 17.0 bits; conditional E-value: 7.8e-06 TPR_1 4 lynlGnayfklgkydeAleyyekALel 30 + l+n+++ lg+yd+A ekALel FUN_001881-T1 406 YGHLANVHRVLGDYDKAYLLHEKALEL 432 789***********************9 PP == domain 10 score: 17.3 bits; conditional E-value: 6.1e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALe 29 k + nlG +++ g+y +A +y+++AL FUN_001881-T1 449 KEYSNLGSLCHCRGEYVKAQKYFKRALC 476 579***********************95 PP == domain 11 score: 0.0 bits; conditional E-value: 1.8 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ++l nl+ + ++lg+ ++ +y e+A ++ FUN_001881-T1 489 DILINLASLELSLGEEEKSKQYRERAHQI 517 5789*************999998888776 PP == domain 12 score: 1.8 bits; conditional E-value: 0.5 TPR_1 14 lgkydeAleyyekAL 28 g++ A ey ek+L FUN_001881-T1 541 VGDFSRAMEYHEKVL 555 59***********99 PP == domain 13 score: 26.0 bits; conditional E-value: 1.1e-08 TPR_1 8 GnayfklgkydeAleyyekALeln 31 G+++++lg++ +A+eyy++AL ++ FUN_001881-T1 575 GQCHMSLGDHSKAIEYYQRALAIY 598 9********************986 PP == domain 14 score: 12.2 bits; conditional E-value: 0.00026 TPR_1 5 ynlGnayfklgkydeAleyyekALeln 31 +n+G y+ + +y eA+ + +kAL++ FUN_001881-T1 612 NNMGTSYLLQWNYREAEGCLNKALSIA 638 8***********************997 PP == domain 15 score: -0.8 bits; conditional E-value: 3.3 TPR_1 4 lynlGnayfklgkydeAl 21 l l++++ + g+ +eA FUN_001881-T1 651 LAHLAALCISRGNNEEAF 668 6789************95 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0046 3.2 8 32 .. 18 42 .. 15 44 .. 0.86 2 ? -0.1 0.0 2.9 2e+03 11 29 .. 68 86 .. 66 91 .. 0.85 3 ? 2.8 0.0 0.34 2.3e+02 16 30 .. 138 152 .. 126 152 .. 0.89 4 ? 2.1 0.1 0.57 3.9e+02 8 27 .. 163 182 .. 160 194 .. 0.74 5 ! 13.1 0.0 0.00017 0.11 4 30 .. 206 232 .. 203 233 .. 0.93 6 ! 17.1 0.0 9.1e-06 0.0063 4 32 .. 246 274 .. 244 276 .. 0.93 7 ! 14.3 0.1 7e-05 0.048 1 31 [. 283 313 .. 283 315 .. 0.92 8 ! 12.1 0.0 0.00035 0.24 4 30 .. 326 352 .. 323 355 .. 0.90 9 ! 25.8 0.0 1.4e-08 9.6e-06 2 30 .. 364 392 .. 363 393 .. 0.94 10 ! 10.6 0.4 0.0011 0.73 4 30 .. 406 432 .. 403 435 .. 0.90 11 ! 14.8 0.3 4.8e-05 0.033 2 28 .. 449 475 .. 448 475 .. 0.95 12 ? 0.7 0.1 1.6 1.1e+03 3 32 .. 490 519 .. 488 521 .. 0.89 13 ! 24.6 0.1 3.4e-08 2.3e-05 3 31 .. 570 598 .. 568 600 .. 0.93 14 ! 15.5 0.0 2.9e-05 0.02 5 32 .. 612 639 .. 609 641 .. 0.92 15 ? 0.8 0.0 1.5 1e+03 3 24 .. 650 671 .. 648 678 .. 0.83 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0046 TPR_2 8 GlayyklgdyeeAleayekAleldP 32 + ++++ +y +A+e+++++l l + FUN_001881-T1 18 ASVLLQIRRYGKAIELFNECLVLLE 42 6789999**************8866 PP == domain 2 score: -0.1 bits; conditional E-value: 2.9 TPR_2 11 yyklgdyeeAleayekAle 29 y gd+++Al+ ekA + FUN_001881-T1 68 YCLVGDHARALQSGEKAHA 86 77789********999976 PP == domain 3 score: 2.8 bits; conditional E-value: 0.34 TPR_2 16 dyeeAleayekAlel 30 +y +A++++e Ale+ FUN_001881-T1 138 NYSQAKDCFEGALEI 152 8***********986 PP == domain 4 score: 2.1 bits; conditional E-value: 0.57 TPR_2 8 GlayyklgdyeeAleayekA 27 G+ + lgd+ Al+ y+++ FUN_001881-T1 163 GKTLSLLGDLFNALKEYRRS 182 77777788888888888875 PP == domain 5 score: 13.1 bits; conditional E-value: 0.00017 TPR_2 4 lynlGlayyklgdyeeAleayekAlel 30 l +lG+++ lg+yeeA+ + ++Al++ FUN_001881-T1 206 LSCLGRVCCILGEYEEAKSLQKRALAI 232 889**********************97 PP == domain 6 score: 17.1 bits; conditional E-value: 9.1e-06 TPR_2 4 lynlGlayyklgdyeeAleayekAleldP 32 + nl+++++ + + +eA++++ kAl+++ FUN_001881-T1 246 YRNLANVHASMSEVDEAKKCFSKALAICK 274 89************************986 PP == domain 7 score: 14.3 bits; conditional E-value: 7e-05 TPR_2 1 aealynlGlayyklgdyeeAleayekAleld 31 a+ ++ lG y+ l++++eA+e+++ A +l+ FUN_001881-T1 283 AKTYHVLGGFYRCLNNHNEAIECFRLACALF 313 678999*********************9986 PP == domain 8 score: 12.1 bits; conditional E-value: 0.00035 TPR_2 4 lynlGlayyklgdyeeAleayekAlel 30 + +lG +y g+++eA+++ ekAl + FUN_001881-T1 326 YSELGALYCSVGRFDEARQCHEKALVI 352 889********************9976 PP == domain 9 score: 25.8 bits; conditional E-value: 1.4e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ nlG +y++lgd+ +A+e+y++Al+ FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRALAV 392 69*************************86 PP == domain 10 score: 10.6 bits; conditional E-value: 0.0011 TPR_2 4 lynlGlayyklgdyeeAleayekAlel 30 + l+++++ lgdy++A + ekAlel FUN_001881-T1 406 YGHLANVHRVLGDYDKAYLLHEKALEL 432 5679*********************98 PP == domain 11 score: 14.8 bits; conditional E-value: 4.8e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAl 28 + + nlG ++ +g+y +A +++++Al FUN_001881-T1 449 KEYSNLGSLCHCRGEYVKAQKYFKRAL 475 5799**********************8 PP == domain 12 score: 0.7 bits; conditional E-value: 1.6 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 +l nl+ + + lg+ e+ +++ e+A ++++ FUN_001881-T1 490 ILINLASLELSLGEEEKSKQYRERAHQIAE 519 789******************999999875 PP == domain 13 score: 24.6 bits; conditional E-value: 3.4e-08 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 +++ G++++ lgd+ +A+e+y++Al+++ FUN_001881-T1 570 CYHDTGQCHMSLGDHSKAIEYYQRALAIY 598 68899*********************997 PP == domain 14 score: 15.5 bits; conditional E-value: 2.9e-05 TPR_2 5 ynlGlayyklgdyeeAleayekAleldP 32 +n+G +y+ + +y eA+ +++kAl++++ FUN_001881-T1 612 NNMGTSYLLQWNYREAEGCLNKALSIAE 639 799*********************9986 PP == domain 15 score: 0.8 bits; conditional E-value: 1.5 TPR_2 3 alynlGlayyklgdyeeAleay 24 +l l+ +++ +g+ eeA ++ FUN_001881-T1 650 VLAHLAALCISRGNNEEAFSHL 671 67889*************8776 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 4.4 3e+03 9 34 .. 18 43 .. 16 45 .. 0.86 2 ? 0.3 0.0 1.6 1.1e+03 11 32 .. 67 88 .. 66 91 .. 0.88 3 ? 0.6 0.0 1.3 9.2e+02 11 25 .. 87 101 .. 86 108 .. 0.86 4 ? 3.6 0.0 0.15 1e+02 16 34 .. 137 155 .. 134 156 .. 0.90 5 ? 4.0 0.3 0.11 77 4 34 .. 165 195 .. 164 196 .. 0.91 6 ! 14.0 0.0 8.1e-05 0.056 3 32 .. 204 233 .. 202 235 .. 0.93 7 ! 13.9 0.0 8.3e-05 0.057 5 35 .. 246 276 .. 246 276 .. 0.95 8 ! 12.3 0.0 0.00027 0.18 2 31 .. 283 312 .. 283 316 .. 0.91 9 ! 19.5 0.0 1.4e-06 0.00099 5 34 .. 326 355 .. 326 356 .. 0.93 10 ! 14.3 0.0 6.3e-05 0.043 3 31 .. 364 392 .. 363 392 .. 0.95 11 ! 10.1 0.3 0.0014 0.94 5 35 .. 406 436 .. 406 440 .. 0.92 12 ! 7.8 0.0 0.0071 4.9 5 35 .. 451 481 .. 451 484 .. 0.93 13 ? 1.2 0.2 0.85 5.9e+02 4 33 .. 490 519 .. 489 521 .. 0.90 14 ? 6.9 0.0 0.014 9.5 14 35 .. 540 561 .. 535 561 .. 0.91 15 ! 11.6 0.0 0.00043 0.3 3 34 .. 569 600 .. 568 601 .. 0.90 16 ! 12.0 0.2 0.00034 0.23 6 35 .. 612 641 .. 612 642 .. 0.96 17 ? 2.1 0.0 0.43 2.9e+02 4 30 .. 650 676 .. 648 678 .. 0.84 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 4.4 TPR_10 9 analraqgryeeAeelleealairer 34 a +l + +ry A el+ e+l + e+ FUN_001881-T1 18 ASVLLQIRRYGKAIELFNECLVLLEK 43 78899999***********9988776 PP == domain 2 score: 0.3 bits; conditional E-value: 1.6 TPR_10 11 alraqgryeeAeelleealair 32 +++ g++++A++ e+a a++ FUN_001881-T1 67 LYCLVGDHARALQSGEKAHAMH 88 68889*************9987 PP == domain 3 score: 0.6 bits; conditional E-value: 1.3 TPR_10 11 alraqgryeeAeell 25 ++++ g+ ++Ae+ll FUN_001881-T1 87 MHSQSGNIDGAEALL 101 899**********98 PP == domain 4 score: 3.6 bits; conditional E-value: 0.15 TPR_10 16 gryeeAeelleealairer 34 +y A + +e al+i+++ FUN_001881-T1 137 FNYSQAKDCFEGALEIWKE 155 79***************98 PP == domain 5 score: 4.0 bits; conditional E-value: 0.11 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 +l+ L+ + a+++y ++ lle+al i e+ FUN_001881-T1 165 TLSLLGDLFNALKEYRRSKLLLERALVILEE 195 688899999*****************99887 PP == domain 6 score: 14.0 bits; conditional E-value: 8.1e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealair 32 ++l+ L+++ + +g+yeeA l+++alai FUN_001881-T1 204 NTLSCLGRVCCILGEYEEAKSLQKRALAIS 233 58999***********************95 PP == domain 7 score: 13.9 bits; conditional E-value: 8.3e-05 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + nLan++ ++ + +eA + + +alai++++ FUN_001881-T1 246 YRNLANVHASMSEVDEAKKCFSKALAICKET 276 67**************************985 PP == domain 8 score: 12.3 bits; conditional E-value: 0.00027 TPR_10 2 asslnnLanalraqgryeeAeelleealai 31 a +++ L+ +r +++++eA e ++ a a+ FUN_001881-T1 283 AKTYHVLGGFYRCLNNHNEAIECFRLACAL 312 679**********************99886 PP == domain 9 score: 19.5 bits; conditional E-value: 1.4e-06 TPR_10 5 lnnLanalraqgryeeAeelleealairer 34 ++ L++++++ gr++eA++ +e+al i ++ FUN_001881-T1 326 YSELGALYCSVGRFDEARQCHEKALVIKKE 355 689**********************99887 PP == domain 10 score: 14.3 bits; conditional E-value: 6.3e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealai 31 ++++nL+ ++ a+g+ A e +++ala+ FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRALAV 392 58*************************96 PP == domain 11 score: 10.1 bits; conditional E-value: 0.0014 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + +Lan++r +g+y+ A l+e+al++ r+ FUN_001881-T1 406 YGHLANVHRVLGDYDKAYLLHEKALELKNRT 436 679***********************98887 PP == domain 12 score: 7.8 bits; conditional E-value: 0.0071 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 ++nL+ + +g+y A +++++al i ++ FUN_001881-T1 451 YSNLGSLCHCRGEYVKAQKYFKRALCIIQEM 481 79************************99875 PP == domain 13 score: 1.2 bits; conditional E-value: 0.85 TPR_10 4 slnnLanalraqgryeeAeelleealaire 33 +l nLa + ++g+ e + ++ e+a +i+e FUN_001881-T1 490 ILINLASLELSLGEEEKSKQYRERAHQIAE 519 588******************999999987 PP == domain 14 score: 6.9 bits; conditional E-value: 0.014 TPR_10 14 aqgryeeAeelleealairerv 35 + g++ +A+e++e++l +r+ FUN_001881-T1 540 SVGDFSRAMEYHEKVLSSSKRL 561 569**************99996 PP == domain 15 score: 11.6 bits; conditional E-value: 0.00043 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++++ ++ + ++g++ A e++++alai+++ FUN_001881-T1 569 SCYHDTGQCHMSLGDHSKAIEYYQRALAIYQA 600 67888888899*******************96 PP == domain 16 score: 12.0 bits; conditional E-value: 0.00034 TPR_10 6 nnLanalraqgryeeAeelleealairerv 35 nn+++ + q +y eAe l +al i+e++ FUN_001881-T1 612 NNMGTSYLLQWNYREAEGCLNKALSIAEEI 641 9**************************985 PP == domain 17 score: 2.1 bits; conditional E-value: 0.43 TPR_10 4 slnnLanalraqgryeeAeelleeala 30 l +La++ ++g+ eeA +l +++ FUN_001881-T1 650 VLAHLAALCISRGNNEEAFSHLLSSVK 676 5789999999*********99877665 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 0.085 59 4 28 .. 16 40 .. 15 47 .. 0.83 2 ? -0.8 0.0 4.7 3.3e+03 7 21 .. 66 80 .. 61 91 .. 0.82 3 ? 1.6 0.6 0.8 5.6e+02 1 31 [. 165 195 .. 165 200 .. 0.86 4 ? 3.4 0.1 0.21 1.4e+02 4 29 .. 208 233 .. 205 240 .. 0.83 5 ! 7.8 0.0 0.0081 5.6 3 35 .. 247 279 .. 246 280 .. 0.94 6 ? 6.8 0.0 0.017 11 2 24 .. 286 308 .. 285 319 .. 0.89 7 ! 17.9 0.0 4.8e-06 0.0033 3 35 .. 327 359 .. 326 360 .. 0.91 8 ! 16.6 0.0 1.2e-05 0.0084 1 33 [. 365 395 .. 365 398 .. 0.86 9 ! 15.8 0.1 2.2e-05 0.015 3 33 .. 407 437 .. 406 440 .. 0.88 10 ! 16.0 0.0 1.9e-05 0.013 2 28 .. 451 477 .. 450 484 .. 0.90 11 ! 9.5 0.0 0.0024 1.6 11 35 .. 540 564 .. 532 565 .. 0.90 12 ! 15.2 0.1 3.5e-05 0.024 6 30 .. 575 599 .. 571 605 .. 0.88 13 ? 2.3 0.0 0.48 3.3e+02 4 34 .. 613 643 .. 612 645 .. 0.86 14 ? 2.1 0.0 0.57 3.9e+02 2 20 .. 651 669 .. 650 680 .. 0.86 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.085 TPR_7 4 aLariyrklGdydeAirlyerlLal 28 a a+++ + ++y +Ai+l+ ++L l FUN_001881-T1 16 AVASVLLQIRRYGKAIELFNECLVL 40 568999*************998844 PP == domain 2 score: -0.8 bits; conditional E-value: 4.7 TPR_7 7 riyrklGdydeAirl 21 ++y+ Gd +A++ FUN_001881-T1 66 SLYCLVGDHARALQS 80 6899********986 PP == domain 3 score: 1.6 bits; conditional E-value: 0.8 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 +Ls+L++++ +l +y++ l+er+L + ++ FUN_001881-T1 165 TLSLLGDLFNALKEYRRSKLLLERALVILEE 195 699*********************9976655 PP == domain 4 score: 3.4 bits; conditional E-value: 0.21 TPR_7 4 aLariyrklGdydeAirlyerlLala 29 L+r+++ lG+y+eA +l +r+La++ FUN_001881-T1 208 CLGRVCCILGEYEEAKSLQKRALAIS 233 59999999*******99999988775 PP == domain 5 score: 7.8 bits; conditional E-value: 0.0081 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La+++ ++ + deA +++ ++La++k+ +d+ FUN_001881-T1 247 RNLANVHASMSEVDEAKKCFSKALAICKETGDK 279 59***************************9997 PP == domain 6 score: 6.8 bits; conditional E-value: 0.017 TPR_7 2 LsaLariyrklGdydeAirlyer 24 ++ L+ +yr l++ eAi++++ FUN_001881-T1 286 YHVLGGFYRCLNNHNEAIECFRL 308 789*****************986 PP == domain 7 score: 17.9 bits; conditional E-value: 4.8e-06 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 s L+ +y++ G++deA +++e++L ++k+ +d+ FUN_001881-T1 327 SELGALYCSVGRFDEARQCHEKALVIKKEIGDK 359 689*********************999998876 PP == domain 8 score: 16.6 bits; conditional E-value: 1.2e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpe 33 a+s+L+++y++lGd +A ++y+r ala d e FUN_001881-T1 365 AYSNLGSLYMALGDPGKAKECYKR--ALAVDVE 395 799*********************..6655554 PP == domain 9 score: 15.8 bits; conditional E-value: 2.2e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpe 33 + La+++r lGdyd+A l+e++L+l+++ + FUN_001881-T1 407 GHLANVHRVLGDYDKAYLLHEKALELKNRTN 437 579*******************999987655 PP == domain 10 score: 16.0 bits; conditional E-value: 1.9e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLal 28 +s+L+++++ +G+y +A ++++r+L + FUN_001881-T1 451 YSNLGSLCHCRGEYVKAQKYFKRALCI 477 58*********************8866 PP == domain 11 score: 9.5 bits; conditional E-value: 0.0024 TPR_7 11 klGdydeAirlyerlLalakdpedr 35 + Gd+ +A +++e++L+ +k+++d+ FUN_001881-T1 540 SVGDFSRAMEYHEKVLSSSKRLGDK 564 68***************99999986 PP == domain 12 score: 15.2 bits; conditional E-value: 3.5e-05 TPR_7 6 ariyrklGdydeAirlyerlLalak 30 ++++++lGd +Ai++y+r+La+ + FUN_001881-T1 575 GQCHMSLGDHSKAIEYYQRALAIYQ 599 6899***************999976 PP == domain 13 score: 2.3 bits; conditional E-value: 0.48 TPR_7 4 aLariyrklGdydeAirlyerlLalakdped 34 +++ y + +y+eA++++ ++L++a++ +d FUN_001881-T1 613 NMGTSYLLQWNYREAEGCLNKALSIAEEIRD 643 6788899999*************99988776 PP == domain 14 score: 2.1 bits; conditional E-value: 0.57 TPR_7 2 LsaLariyrklGdydeAir 20 L+ La ++ ++G+ +eA + FUN_001881-T1 651 LAHLAALCISRGNNEEAFS 669 789*************966 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.068 47 8 28 .. 18 38 .. 15 40 .. 0.92 2 ? 2.2 0.0 0.55 3.8e+02 16 30 .. 138 152 .. 127 152 .. 0.90 3 ? 1.8 0.0 0.75 5.1e+02 4 28 .. 166 190 .. 163 191 .. 0.87 4 ? 5.5 0.1 0.047 32 13 30 .. 215 232 .. 209 233 .. 0.84 5 ! 10.2 0.1 0.0015 1 6 32 .. 248 274 .. 246 276 .. 0.91 6 ! 13.8 0.0 0.0001 0.069 1 30 [. 283 312 .. 283 315 .. 0.93 7 ? 4.1 0.1 0.13 90 6 28 .. 328 350 .. 326 355 .. 0.85 8 ! 25.8 0.1 1.5e-08 1e-05 2 30 .. 364 392 .. 363 393 .. 0.93 9 ? 6.7 0.1 0.019 13 4 32 .. 406 434 .. 406 436 .. 0.92 10 ? 3.2 0.1 0.27 1.8e+02 4 28 .. 451 475 .. 451 478 .. 0.91 11 ? 6.7 0.1 0.02 14 3 30 .. 490 517 .. 488 521 .. 0.85 12 ? 4.3 0.0 0.11 78 3 30 .. 530 557 .. 528 560 .. 0.87 13 ! 19.0 0.1 2.2e-06 0.0015 4 31 .. 571 598 .. 569 600 .. 0.89 14 ? 5.8 0.1 0.037 26 4 32 .. 611 639 .. 609 641 .. 0.90 15 ? -0.8 0.0 5.1 3.5e+03 4 30 .. 651 677 .. 649 680 .. 0.81 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.068 TPR_8 8 GliylklgdyeeAkeyyekal 28 ++++l+ +y +A+e ++++l FUN_001881-T1 18 ASVLLQIRRYGKAIELFNECL 38 78999***************8 PP == domain 2 score: 2.2 bits; conditional E-value: 0.55 TPR_8 16 dyeeAkeyyekalel 30 +y +Ak ++e ale+ FUN_001881-T1 138 NYSQAKDCFEGALEI 152 899**********97 PP == domain 3 score: 1.8 bits; conditional E-value: 0.75 TPR_8 4 yynlGliylklgdyeeAkeyyekal 28 + +lG++ l++y +k +e+al FUN_001881-T1 166 LSLLGDLFNALKEYRRSKLLLERAL 190 5689999999****99999999997 PP == domain 4 score: 5.5 bits; conditional E-value: 0.047 TPR_8 13 klgdyeeAkeyyekalel 30 lg+yeeAk ++al + FUN_001881-T1 215 ILGEYEEAKSLQKRALAI 232 59*************987 PP == domain 5 score: 10.2 bits; conditional E-value: 0.0015 TPR_8 6 nlGliylklgdyeeAkeyyekaleldp 32 nl++++ ++ + +eAk+++ kal + + FUN_001881-T1 248 NLANVHASMSEVDEAKKCFSKALAICK 274 89*********************9865 PP == domain 6 score: 13.8 bits; conditional E-value: 0.0001 TPR_8 1 aeayynlGliylklgdyeeAkeyyekalel 30 a++y+ lG y+ l++++eA+e+++ a+ l FUN_001881-T1 283 AKTYHVLGGFYRCLNNHNEAIECFRLACAL 312 689**********************99866 PP == domain 7 score: 4.1 bits; conditional E-value: 0.13 TPR_8 6 nlGliylklgdyeeAkeyyekal 28 lG +y + g+++eA+++ ekal FUN_001881-T1 328 ELGALYCSVGRFDEARQCHEKAL 350 688889999************98 PP == domain 8 score: 25.8 bits; conditional E-value: 1.5e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y+ lgd +Ake+y++al FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRALAV 392 69************************976 PP == domain 9 score: 6.7 bits; conditional E-value: 0.019 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldp 32 y +l+++++ lgdy++A ekalel+ FUN_001881-T1 406 YGHLANVHRVLGDYDKAYLLHEKALELKN 434 78999*********************986 PP == domain 10 score: 3.2 bits; conditional E-value: 0.27 TPR_8 4 yynlGliylklgdyeeAkeyyekal 28 y nlG++++ g+y +A++y+++al FUN_001881-T1 451 YSNLGSLCHCRGEYVKAQKYFKRAL 475 67899999999************97 PP == domain 11 score: 6.7 bits; conditional E-value: 0.02 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ++ nl+++ l+lg+ e++k+y e+a ++ FUN_001881-T1 490 ILINLASLELSLGEEEKSKQYRERAHQI 517 789******************8888655 PP == domain 12 score: 4.3 bits; conditional E-value: 0.11 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 +y +G++ ++ gd+ A+ey ek+l+ FUN_001881-T1 530 VYDIMGKAGQSVGDFSRAMEYHEKVLSS 557 67788999999**************986 PP == domain 13 score: 19.0 bits; conditional E-value: 2.2e-06 TPR_8 4 yynlGliylklgdyeeAkeyyekaleld 31 y+ G+++++lgd+ +A+eyy++al + FUN_001881-T1 571 YHDTGQCHMSLGDHSKAIEYYQRALAIY 598 67779********************886 PP == domain 14 score: 5.8 bits; conditional E-value: 0.037 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldp 32 +n+G yl + +y eA+ +++kal++++ FUN_001881-T1 611 NNNMGTSYLLQWNYREAEGCLNKALSIAE 639 679999999999***************97 PP == domain 15 score: -0.8 bits; conditional E-value: 5.1 TPR_8 4 yynlGliylklgdyeeAkeyyekalel 30 + +l+ ++++ g+ eeA + ++++ FUN_001881-T1 651 LAHLAALCISRGNNEEAFSHLLSSVKI 677 567899999********8887776665 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 0.0 0.024 16 6 31 .. 16 41 .. 13 47 .. 0.87 2 ? -0.4 0.0 5.9 4.1e+03 11 28 .. 88 105 .. 82 108 .. 0.83 3 ? 1.4 0.3 1.6 1.1e+03 6 36 .. 168 198 .. 164 202 .. 0.82 4 ? -0.2 0.0 5.4 3.7e+03 7 29 .. 209 231 .. 204 233 .. 0.81 5 ? 6.4 0.0 0.039 27 4 33 .. 246 275 .. 243 278 .. 0.90 6 ? 5.4 0.0 0.082 57 4 31 .. 286 313 .. 283 318 .. 0.89 7 ? 5.0 0.0 0.11 77 6 28 .. 328 350 .. 324 355 .. 0.88 8 ! 14.7 0.0 7.9e-05 0.055 4 37 .. 366 399 .. 364 406 .. 0.82 9 ? 7.6 0.1 0.016 11 7 30 .. 409 432 .. 406 439 .. 0.90 10 ? 4.1 0.0 0.2 1.4e+02 7 28 .. 454 475 .. 449 478 .. 0.89 11 ? -0.1 0.1 4.8 3.3e+03 3 30 .. 490 517 .. 489 527 .. 0.84 12 ? 0.2 0.0 3.7 2.6e+03 5 28 .. 532 555 .. 529 559 .. 0.81 13 ! 12.2 0.0 0.0005 0.35 5 31 .. 572 598 .. 569 601 .. 0.88 14 ? 1.1 0.0 2 1.4e+03 4 26 .. 651 673 .. 649 679 .. 0.85 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.024 TPR_14 6 alarallalGdpdeAlelleralald 31 a a +ll+ ++ +A+el++++l l FUN_001881-T1 16 AVASVLLQIRRYGKAIELFNECLVLL 41 6799******************9875 PP == domain 2 score: -0.4 bits; conditional E-value: 5.9 TPR_14 11 llalGdpdeAlelleral 28 + + G+ d A++ll ++ FUN_001881-T1 88 HSQSGNIDGAEALLSKMF 105 6789**********9875 PP == domain 3 score: 1.4 bits; conditional E-value: 1.6 TPR_14 6 alarallalGdpdeAlelleralaldPddpe 36 +l++++ al+++ + lleral + + FUN_001881-T1 168 LLGDLFNALKEYRRSKLLLERALVILEEAKD 198 689999****************987666555 PP == domain 4 score: -0.2 bits; conditional E-value: 5.4 TPR_14 7 larallalGdpdeAlellerala 29 l+r++ lG+++eA l +rala FUN_001881-T1 209 LGRVCCILGEYEEAKSLQKRALA 231 78889999******988777765 PP == domain 5 score: 6.4 bits; conditional E-value: 0.039 TPR_14 4 wlalarallalGdpdeAlelleralaldPd 33 ++ la++++ + deA +++ +ala + + FUN_001881-T1 246 YRNLANVHASMSEVDEAKKCFSKALAICKE 275 6789**********************9976 PP == domain 6 score: 5.4 bits; conditional E-value: 0.082 TPR_14 4 wlalarallalGdpdeAlelleralald 31 ++ l+ +++ l+++ eA+e+++ a+al+ FUN_001881-T1 286 YHVLGGFYRCLNNHNEAIECFRLACALF 313 778999******************9987 PP == domain 7 score: 5.0 bits; conditional E-value: 0.11 TPR_14 6 alarallalGdpdeAlelleral 28 l++++ G++deA+++ e+al FUN_001881-T1 328 ELGALYCSVGRFDEARQCHEKAL 350 6899999*************998 PP == domain 8 score: 14.7 bits; conditional E-value: 7.9e-05 TPR_14 4 wlalarallalGdpdeAlelleralaldPddpea 37 + l+ +++alGdp +A e+++rala d + + FUN_001881-T1 366 YSNLGSLYMALGDPGKAKECYKRALAVDVETNSL 399 556999*******************988666555 PP == domain 9 score: 7.6 bits; conditional E-value: 0.016 TPR_14 7 larallalGdpdeAlelleralal 30 la++++ lGd+d+A l e+al+l FUN_001881-T1 409 LANVHRVLGDYDKAYLLHEKALEL 432 89*******************996 PP == domain 10 score: 4.1 bits; conditional E-value: 0.2 TPR_14 7 larallalGdpdeAlelleral 28 l+ ++ +G++ +A ++++ral FUN_001881-T1 454 LGSLCHCRGEYVKAQKYFKRAL 475 7889999**************8 PP == domain 11 score: -0.1 bits; conditional E-value: 4.8 TPR_14 3 awlalarallalGdpdeAlelleralal 30 +++ la ++l lG+ ++ ++ era++ FUN_001881-T1 490 ILINLASLELSLGEEEKSKQYRERAHQI 517 577899********99999999999775 PP == domain 12 score: 0.2 bits; conditional E-value: 3.7 TPR_14 5 lalarallalGdpdeAlelleral 28 +++a Gd+++A+e+ e+ l FUN_001881-T1 532 DIMGKAGQSVGDFSRAMEYHEKVL 555 5667777889*********99987 PP == domain 13 score: 12.2 bits; conditional E-value: 0.0005 TPR_14 5 lalarallalGdpdeAlelleralald 31 + ++ ++ lGd+++A+e+++rala + FUN_001881-T1 572 HDTGQCHMSLGDHSKAIEYYQRALAIY 598 667899******************986 PP == domain 14 score: 1.1 bits; conditional E-value: 2 TPR_14 4 wlalarallalGdpdeAleller 26 ++ la+++ +G+ +eA +l + FUN_001881-T1 651 LAHLAALCISRGNNEEAFSHLLS 673 6789*************998865 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.0 5.6e-05 0.039 91 174 .. 195 276 .. 191 280 .. 0.86 2 ! 15.6 0.0 1.7e-05 0.011 141 216 .. 283 356 .. 277 364 .. 0.78 3 ! 19.7 0.2 9.3e-07 0.00065 100 217 .. 364 482 .. 360 499 .. 0.81 4 ! 20.9 0.0 3.9e-07 0.00027 46 223 .. 476 648 .. 475 657 .. 0.73 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 5.6e-05 TPR_NPHP3 91 geltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 + ++l ++ ++ +lGr ++ lg + a + +raL i + +a + +La+++a + + a++ + +al+i++++ FUN_001881-T1 195 EAKDLRELGNTLSCLGRVCCILGEYEEAKSLQKRALAISVLL-KERDAEIAD-YRNLANVHASMSEVDEAKKCFSKALAICKET 276 556788899999****************99999*****7655.555556665.689************************9875 PP == domain 2 score: 15.6 bits; conditional E-value: 1.7e-05 TPR_NPHP3 141 arslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravairkka 216 a+++h L g y ++++ a + ++ a +++ + d e+ l +ly ++d a +++++a+ i+k++ FUN_001881-T1 283 AKTYHVLGGFYRCLNNHNEAIECFRLACALFSEVGDRDQ--ESSEYSELGALYCSVGRFDEARQCHEKALVIKKEI 356 788899999999999999999999999888877654444..45788889999999999999999999999998875 PP == domain 3 score: 19.7 bits; conditional E-value: 9.3e-07 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye...nayGsdhelvakelealall 192 d y lG lg +a + +raL + + + a + +La+++ g +++a l+++ale+++ + +d e++ ke+ l l FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRALAVDVETNSLRE--QAIDYGHLANVHRVLGDYDKAYLLHEKALELKNrtnENTEEDKESLCKEYSNLGSL 457 67899999999999999999999999988643322222..3556789**********************997611144568999************ PP TPR_NPHP3 193 yqkqdkhdlaeplkkravairkkak 217 + + + a+ kra+ i +++ FUN_001881-T1 458 CHCRGEYVKAQKYFKRALCIIQEMV 482 ******************9987754 PP == domain 4 score: 20.9 bits; conditional E-value: 3.9e-07 TPR_NPHP3 46 svfqrlyargrcaellsyWqyvg..adksklakaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl 139 ++ q+++ r ++l ++ ++ +k+Y + ++++ +a ++e + ++y+++G+ + +g s+a++ ++ L D+ FUN_001881-T1 476 CIIQEMVDRRAEGDILINLASLElsLGEEEKSKQYRERAHQIAEACGSE---IAIQQVYDIMGKAGQSVGDFSRAMEYHEKVLSSSKRL--GDKRC 566 5666666666666655555444311345666778888888887775444...4566778888988888888888888888888755444..79999 PP TPR_NPHP3 140 varslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqkqdkhdlaeplkkravairkkakkskakl 223 ++ +h + + g +s+a ++y++al+iy+ + + e+v+++ + + y q + ae + ++a++i ++++ ++k+ FUN_001881-T1 567 EGSCYHDTGQCHMSLGDHSKAIEYYQRALAIYQAIGEKRGEVVINN--NMGTSYLLQWNYREAEGCLNKALSIAEEIRDLEGKS 648 9*******************************97655555566655..5666677777899************99988766654 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.1 1e-06 0.0007 24 187 .. 186 349 .. 163 355 .. 0.88 2 ! 33.2 0.3 6.8e-11 4.7e-08 10 192 .. 332 519 .. 330 530 .. 0.88 3 ! 17.2 0.1 4.9e-06 0.0034 43 182 .. 531 669 .. 526 676 .. 0.89 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 1e-06 TPR_MalT 24 AreALallped.dllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqeskleal 118 ++AL +l+e dl + + ++++lG++ ++g+ e+A++ + a a++ + ++ + ++ +a+++ + +A + + +al+ +e++ + FUN_001881-T1 186 LERALVILEEAkDLRELGNTLSCLGRVCCILGEYEEAKSLQKRALAISVLLKERDAEIADYRNLANVHASMSEVDEAKKCFSKALAICKETGDKS- 280 5899999998725555699*************************9999999999999**********************************9995. PP TPR_MalT 119 plvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqra 187 + + l+ ++ n eA ++ + +++l ++ ++++ y l + + G+ +eA++ ++a FUN_001881-T1 281 -GEAKTYHVLGGFYRCLNNHNEAIECFRLACALFSEVgDRDQESSEYSELGALYCSVGRFDEARQCHEKA 349 .555555667**************************9788***********************9988777 PP == domain 2 score: 33.2 bits; conditional E-value: 6.8e-11 TPR_MalT 10 lavsqgeaeeaeelAreALallpeddllar..tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaety 103 l+ s g+++ea++ ++AL + +e r + a+++lG ++++gd +A++ ++ a a + +sl+ ++ + ++a+++r G+ +A+ + FUN_001881-T1 332 LYCSVGRFDEARQCHEKALVIKKEIG-DKRgeGDAYSNLGSLYMALGDPGKAKECYKRALAVDVETNSLREQAIDYGHLANVHRVLGDYDKAYLLH 426 78899999999999999998877643.4443389************************************************************** PP TPR_MalT 104 qqalqlaqesklealplvgfl...lvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerlar 192 ++al+l ++++++ + + l + l+ L + +++ +A+++ ++++ + +++ +++a ++ + la++ l+ Ge e ++++ +ra ++a+ FUN_001881-T1 427 EKALELKNRTNENTEEDKESLckeYSNLGSLCHCRGEYVKAQKYFKRALCIIQEMvDRRAEGDILINLASLELSLGEEEKSKQYRERAHQIAE 519 *******9998887765555501155667889********************998799******************************99987 PP == domain 3 score: 17.2 bits; conditional E-value: 4.9e-06 TPR_MalT 43 tlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwndL 138 + +G a + gd++ A + +++ ++++r ++ + + ++ ++ G+ +A+e yq+al+ q ++++ ++v +g + L + wn FUN_001881-T1 531 YDIMGKAGQSVGDFSRAMEYHEKVLSSSKRLGDKRCEGSCYHDTGQCHMSLGDHSKAIEYYQRALAIYQAIGEKRGEVVINNNMGTSYL-LQWNY- 624 56799*****************************9888888899999****************************99999888886665.57985. PP TPR_MalT 139 eeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAet 182 eAe +l +++ ++++ + + la +++++G+ eeA + FUN_001881-T1 625 REAEGCLNKALSIAEEIrDLEGKSTVLAHLAALCISRGNNEEAFS 669 89**************9555888889999*************965 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 7.6 5.2e+03 161 180 .. 17 36 .. 13 38 .. 0.84 2 ? 3.7 0.0 0.073 50 42 100 .. 130 196 .. 91 232 .. 0.66 3 ! 18.6 1.7 2.1e-06 0.0015 40 141 .. 248 349 .. 237 350 .. 0.74 4 ! 18.6 0.6 2.2e-06 0.0015 48 180 .. 336 473 .. 325 484 .. 0.81 5 ! 10.8 0.3 0.00051 0.35 50 144 .. 543 637 .. 505 669 .. 0.81 6 ? 3.0 0.0 0.12 83 43 107 .. 616 681 .. 610 698 .. 0.80 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 7.6 SNAP 161 vAdlsaelekyekAieiyek 180 vA++ + ++y kAie++++ FUN_001881-T1 17 VASVLLQIRRYGKAIELFNE 36 7888889999******9986 PP == domain 2 score: 3.7 bits; conditional E-value: 0.073 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanay......veAakcykks..dpeeAvealekA 100 ++++k + ++++A ++f+ a e+ ++++++ e ++++ ++A k y++s e+A+ le+A FUN_001881-T1 130 GTKFKSDFNYSQAKDCFEGALEIWKEIGNRREEGKTLsllgdlFNALKEYRRSklLLERALVILEEA 196 5677777777777777777777777777777777764111111344444444411223444444444 PP == domain 3 score: 18.6 bits; conditional E-value: 2.1e-06 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + An +++eA ++f ka ++ +++++k+ a++y y+ + +eA+e+++ A +++ e g ++ ++ + e++ ly + +++++A FUN_001881-T1 248 NLANVHASMSEVDEAKKCFSKALAICKETGDKSGEAKTYHVLGGFYRCLnNHNEAIECFRLACALFSEVGDRDQESSEYSELGALYCSV-GRFDEA 342 55666666677888888888887777777777777777777777776652566888888888888888888888888888888888877.888888 PP SNAP 135 ieaYeqA 141 ++ e+A FUN_001881-T1 343 RQCHEKA 349 8888887 PP == domain 4 score: 18.6 bits; conditional E-value: 2.2e-06 SNAP 48 akkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAa 142 +++eA ++++ka +++++++k ++ay + y dp +A e++++A ++ +e +++r+ A + ++a++ + +d++kA e+A FUN_001881-T1 336 VGRFDEARQCHEKALVIKKEIGDKRGEGDAYSNLGSLYMALgDPGKAKECYKRALAVDVETNSLREQAIDYGHLANVHRVL-GDYDKAYLLHEKAL 430 56899*****************************99998876***********************************9977.************** PP SNAP 143 dlyeqeeaeal..ankcllkvAdl...saelekyekAieiyek 180 +l + + +++ ++++ ++ +l ++y kA + +++ FUN_001881-T1 431 ELKNRTNENTEedKESLCKEYSNLgslCHCRGEYVKAQKYFKR 473 *977655444400444444444441104445588888777765 PP == domain 5 score: 10.8 bits; conditional E-value: 0.00051 SNAP 50 kwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadl 144 ++++A e ++k+ + +++l++k +++y + +c + d ++A+e +++A +iy++ g+ r + +++ y + ++++A + ++A + FUN_001881-T1 543 DFSRAMEYHEKVLSSSKRLGDKRCEGSCYHDTGQCHMSLgDHSKAIEYYQRALAIYQAIGEKRGEVVINNNMGTSYLLQ-WNYREAEGCLNKALSI 637 5778889999999999999****************98876999*****************9998888888888888777.7777777777766655 PP == domain 6 score: 3.0 bits; conditional E-value: 0.12 SNAP 43 nayklakkwkeAgeaflkaAecqeklkekdeaanayve.AakcykksdpeeAvealekAieiytek 107 ++y l+ +++eA + ka ++ e++ + + ++ ++ Aa c+++ ++eeA ++l ++++i ++ FUN_001881-T1 616 TSYLLQWNYREAEGCLNKALSIAEEIRDLEGKSTVLAHlAALCISRGNNEEAFSHLLSSVKIIDDM 681 689999999***************9777666666665449*******************9997654 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 8.7 6e+03 14 23 .. 24 33 .. 24 35 .. 0.83 2 ? -2.2 0.0 7 4.8e+03 7 19 .. 169 181 .. 163 181 .. 0.79 3 ? 2.7 0.0 0.22 1.5e+02 1 13 [. 210 222 .. 210 233 .. 0.78 4 ? 2.5 0.0 0.24 1.7e+02 2 25 .. 251 274 .. 250 276 .. 0.85 5 ? 2.9 0.0 0.18 1.3e+02 5 23 .. 294 312 .. 292 314 .. 0.87 6 ? 6.2 0.0 0.017 12 1 24 [. 330 353 .. 330 355 .. 0.89 7 ? 4.0 0.0 0.08 55 29 42 .] 364 377 .. 364 377 .. 0.95 8 ! 7.6 0.1 0.0062 4.3 1 24 [. 370 393 .. 370 395 .. 0.94 9 ? 1.8 0.0 0.4 2.8e+02 2 25 .. 411 434 .. 410 436 .. 0.87 10 ! 9.9 0.1 0.0012 0.84 4 23 .. 578 597 .. 575 599 .. 0.89 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 8.7 TPR_11 14 ieaYkkAlkl 23 i +Y kA++l FUN_001881-T1 24 IRRYGKAIEL 33 6789999997 PP == domain 2 score: -2.2 bits; conditional E-value: 7 TPR_11 7 qGkyeeAieaYkk 19 +G++ +A+++Y++ FUN_001881-T1 169 LGDLFNALKEYRR 181 799999*****86 PP == domain 3 score: 2.7 bits; conditional E-value: 0.22 TPR_11 1 GdayyeqGkyeeA 13 G++++ +G+yeeA FUN_001881-T1 210 GRVCCILGEYEEA 222 8999********9 PP == domain 4 score: 2.5 bits; conditional E-value: 0.24 TPR_11 2 dayyeqGkyeeAieaYkkAlkldP 25 ++ + + +eA ++++kAl+++ FUN_001881-T1 251 NVHASMSEVDEAKKCFSKALAICK 274 667778899************986 PP == domain 5 score: 2.9 bits; conditional E-value: 0.18 TPR_11 5 yeqGkyeeAieaYkkAlkl 23 + +++ +eAie+++ A++l FUN_001881-T1 294 RCLNNHNEAIECFRLACAL 312 557999********99987 PP == domain 6 score: 6.2 bits; conditional E-value: 0.017 TPR_11 1 GdayyeqGkyeeAieaYkkAlkld 24 G +y++ G+++eA ++ +kAl ++ FUN_001881-T1 330 GALYCSVGRFDEARQCHEKALVIK 353 5579999**************987 PP == domain 7 score: 4.0 bits; conditional E-value: 0.08 TPR_11 29 eayynLGlayykqG 42 +ay+nLG +y+++G FUN_001881-T1 364 DAYSNLGSLYMALG 377 79*********998 PP == domain 8 score: 7.6 bits; conditional E-value: 0.0062 TPR_11 1 GdayyeqGkyeeAieaYkkAlkld 24 G +y+++G+ +A e+Yk+Al+ d FUN_001881-T1 370 GSLYMALGDPGKAKECYKRALAVD 393 789******************987 PP == domain 9 score: 1.8 bits; conditional E-value: 0.4 TPR_11 2 dayyeqGkyeeAieaYkkAlkldP 25 ++ + +G+y++A +kAl+l++ FUN_001881-T1 411 NVHRVLGDYDKAYLLHEKALELKN 434 677779***************986 PP == domain 10 score: 9.9 bits; conditional E-value: 0.0012 TPR_11 4 yyeqGkyeeAieaYkkAlkl 23 +++G+ +Aie Y++Al++ FUN_001881-T1 578 HMSLGDHSKAIEYYQRALAI 597 6899**************97 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 3.5 2.4e+03 123 157 .. 21 57 .. 13 61 .. 0.76 2 ? 4.3 0.0 0.058 40 38 71 .. 60 93 .. 41 96 .. 0.87 3 ? 6.1 0.1 0.016 11 34 72 .. 242 279 .. 235 281 .. 0.88 4 ? 3.4 0.0 0.11 75 38 63 .. 325 350 .. 314 360 .. 0.87 5 ? 6.4 0.0 0.013 9.2 37 68 .. 364 395 .. 352 400 .. 0.88 6 ! 9.7 1.8 0.0013 0.91 15 109 .. 428 524 .. 421 559 .. 0.82 7 ! 12.2 0.2 0.00023 0.16 38 142 .. 570 677 .. 549 692 .. 0.85 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 3.5 RPN7 123 alairkfkeAakllldslstfts..telisyedvavy 157 +l+ir++ +A +l+ ++l +++ +++i++ + a+ FUN_001881-T1 21 LLQIRRYGKAIELFNECLVLLEKhaSQMIDSRRSAFT 57 6899**********99988776666777776666655 PP == domain 2 score: 4.3 bits; conditional E-value: 0.058 RPN7 38 aledlaehyakigdlenAlkayerarekttslgh 71 +e+l+ y+ +gd+ +Al++ e+a+ +++g+ FUN_001881-T1 60 VYERLFSLYCLVGDHARALQSGEKAHAMHSQSGN 93 5899********************9998888775 PP == domain 3 score: 6.1 bits; conditional E-value: 0.016 RPN7 34 eirraledlaehyakigdlenAlkayerarekttslghk 72 ei++ + +la+ +a++ ++++A k++++a+ + +g k FUN_001881-T1 242 EIAD-YRNLANVHASMSEVDEAKKCFSKALAICKETGDK 279 5655.899*************************999876 PP == domain 4 score: 3.4 bits; conditional E-value: 0.11 RPN7 38 aledlaehyakigdlenAlkayerar 63 + +l+ y+++g +++A ++ e+a+ FUN_001881-T1 325 EYSELGALYCSVGRFDEARQCHEKAL 350 5789******************9986 PP == domain 5 score: 6.4 bits; conditional E-value: 0.013 RPN7 37 raledlaehyakigdlenAlkayerarektts 68 +a+ +l+ y++ gd +A ++y+ra+ + FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRALAVDVE 395 5899*********************9876665 PP == domain 6 score: 9.7 bits; conditional E-value: 0.0013 RPN7 15 eleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayer...arekttslghkidlllnlirvgiffndwalvskylekaksliekgg 107 + eL+++ ++ +++ ke++ + + +l+ + g++ +A+k+++r ++++ + + d+l+nl +++ +++ ++ ++y e+a+++ e g FUN_001881-T1 428 KALELKNRTNE-NTEEDKESLCKEYSNLGSLCHCRGEYVKAQKYFKRalcIIQEMVDRRAEGDILINLASLELSLGEEEKSKQYRERAHQIAEACG 522 55677777775.68889999999************************55557999999*********************************99977 PP RPN7 108 dw 109 + FUN_001881-T1 523 SE 524 64 PP == domain 7 score: 12.2 bits; conditional E-value: 0.00023 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki.dlll.nlirvgiffn.dwalvskylekaksliekggdwerrnrlkvyeGlaalairkfk 130 +++d ++ +++ gd+++A+++y+ra+ ++ g k ++++ n + +++ ++ ++ ++ l+ka s+ e+ d e + + + + +++++++ + FUN_001881-T1 570 CYHDTGQCHMSLGDHSKAIEYYQRALAIYQAIGEKRgEVVInNNMGTSYLLQwNYREAEGCLNKALSIAEEIRDLEGKSTVLAHLAALCISRGNNE 665 78999*******************888777777664154442567777766569999*************************************** PP RPN7 131 eAakllldslst 142 eA ++ll+s+ FUN_001881-T1 666 EAFSHLLSSVKI 677 *******99865 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 1.2 8.3e+02 38 56 .. 18 36 .. 16 41 .. 0.85 2 ? -0.7 0.0 4.2 2.9e+03 3 25 .. 249 271 .. 247 271 .. 0.90 3 ! 15.5 0.1 3.8e-05 0.026 3 51 .. 369 423 .. 367 434 .. 0.90 4 ! 12.9 0.0 0.00023 0.16 37 61 .. 574 598 .. 573 600 .. 0.92 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 1.2 TPR_16 38 GlallrqgrlaeAaaayra 56 + +ll+ +r+ +A++++++ FUN_001881-T1 18 ASVLLQIRRYGKAIELFNE 36 6789999999999999986 PP == domain 2 score: -0.7 bits; conditional E-value: 4.2 TPR_16 3 laraalaagdyddAaaaleaalr 25 la+ + + + d+A +++ al+ FUN_001881-T1 249 LANVHASMSEVDEAKKCFSKALA 271 89999999**********99986 PP == domain 3 score: 15.5 bits; conditional E-value: 3.8e-05 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAa 51 l+ +++a+gd+ A +++++al+ + e a + l+ ++ +g++++A FUN_001881-T1 369 LGSLYMALGDPGKAKECYKRALAVDvetnslREQAIDYGHLANVHRVLGDYDKAY 423 899***************************9889999999************995 PP == domain 4 score: 12.9 bits; conditional E-value: 0.00023 TPR_16 37 lGlallrqgrlaeAaaayraalraa 61 +G+++ +g++ +A+++y++al+++ FUN_001881-T1 574 TGQCHMSLGDHSKAIEYYQRALAIY 598 69********************987 PP >> ARM_TT21 Tetratricopeptide repeat protein 21 ARM repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.12 80 13 88 .. 17 89 .. 7 99 .. 0.78 2 ! 8.8 0.1 0.0029 2 53 92 .. 239 278 .. 186 281 .. 0.74 3 ? 2.2 0.0 0.32 2.2e+02 22 84 .. 298 350 .. 281 360 .. 0.66 4 ! 7.7 0.1 0.0064 4.4 14 111 .. 410 505 .. 398 509 .. 0.79 5 ? 1.4 0.0 0.58 4e+02 21 98 .. 535 610 .. 524 616 .. 0.66 6 ? 1.3 0.0 0.61 4.2e+02 65 117 .. 616 671 .. 574 681 .. 0.67 7 ? 0.2 0.0 1.3 8.8e+02 15 78 .. 656 721 .. 640 728 .. 0.70 8 ? -1.7 0.0 5.2 3.6e+03 25 44 .. 1121 1140 .. 1119 1147 .. 0.74 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.12 ARM_TT21 13 kakvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaieefk 88 a+vl + +++ +A+++++++l l +k+ s+ ++++ + vy l ++++ +++ + A + ++a ++++ FUN_001881-T1 17 VASVLLQIRRYGKAIELFNECLVLLEKHASQMIDSRRSA---FTTLVYERLFSLYCLVGDHARALQSGEKAHAMHS 89 5889999999**************998777666554433...4567888888888888888888887777776655 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0029 ARM_TT21 53 esdkvsvylelidvlsklkkveeAkkllqeaieefkgtpe 92 ++ +++ y +l++v++++ +v+eAkk +++a++ k+t + FUN_001881-T1 239 RDAEIADYRNLANVHASMSEVDEAKKCFSKALAICKETGD 278 34567789************************99999876 PP == domain 3 score: 2.2 bits; conditional E-value: 0.32 ARM_TT21 22 kleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeai 84 + +eA+++++ A +l ++ ++ ++ s y el ++++++++++eA++ ++a+ FUN_001881-T1 298 NHNEAIECFRLACALFSEVGDRD----------QESSEYSELGALYCSVGRFDEARQCHEKAL 350 55556666666666644332222..........223448899999999999999999999886 PP == domain 4 score: 7.7 bits; conditional E-value: 0.0064 ARM_TT21 14 akvlkkegkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeai...eefkgtpeevrillanaelala 106 a+v++ g++++A + ++Al+l +++ ++++++ kes ++ y +l ++++ ++ +A+k +++a+ +e + e+ il+ a+l l+ FUN_001881-T1 410 ANVHRVLGDYDKAYLLHEKALELKNRT-NENTEEDKES----LCKEYSNLGSLCHCRGEYVKAQKYFKRALciiQEMVDRRAEGDILINLASLELS 500 8999999****************7654.4444444444....456699999999999999999999999975558888899999999999999998 PP ARM_TT21 107 rgdvd 111 g+ + FUN_001881-T1 501 LGEEE 505 87755 PP == domain 5 score: 1.4 bits; conditional E-value: 0.58 ARM_TT21 21 gkleeAlktLktAlklpgkkkskekkkekessesdkvsvylelidvlsklkkveeAkkllqeaieefkgtpee.vrill 98 gk +++ + A++ +k s++k+ ++ + s y +++++l++ ++A + q+a++ ++ e+ +++++ FUN_001881-T1 535 GKAGQSVGDFSRAMEYHEKVLSSSKRLG---DKRCEGSCYHDTGQCHMSLGDHSKAIEYYQRALAIYQAIGEKrGEVVI 610 5555555566666666554433333211...223456899999999**********99999999999987665244544 PP == domain 6 score: 1.3 bits; conditional E-value: 0.61 ARM_TT21 65 dvlsklkkveeAkkllqeai...eefkgtpeevrillanaelalargdvdkAlelL 117 + + + +eA+ l++a+ ee ++ + ++++l a l+++rg+ ++A + L FUN_001881-T1 616 TSYLLQWNYREAEGCLNKALsiaEEIRDLEGKSTVLAHLAALCISRGNNEEAFSHL 671 44555556677777777776444566666777888888899999999999998754 PP == domain 7 score: 0.2 bits; conditional E-value: 1.3 ARM_TT21 15 kvlkkegkleeAlktLktAlklpg.kkkskekkkekesse.sdkvsvylelidvlsklkkveeAkk 78 ++ ++g++eeA ++L + +k+ + s +++ +++ ++ v y ++ +l+++k+++ A + FUN_001881-T1 656 ALCISRGNNEEAFSHLLSSVKIIDdMRGSLGDSERYQIAFaDKTVGFYRLMATMLCSMKETNLALS 721 455567899999999999999886244444444455555404556677777778888888887765 PP == domain 8 score: -1.7 bits; conditional E-value: 5.2 ARM_TT21 25 eAlktLktAlklpgkkkske 44 A ++L++A+kl++++++ + FUN_001881-T1 1121 SASESLHEAMKLMREDPTYS 1140 68889999999988776554 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 1.3 9e+02 130 153 .] 15 38 .. 4 61 .. 0.65 2 ! 7.6 0.4 0.0085 5.9 22 142 .. 153 286 .. 128 296 .. 0.64 3 ? 2.4 0.0 0.34 2.4e+02 37 104 .. 248 314 .. 242 327 .. 0.74 4 ? -0.2 0.0 2.2 1.5e+03 18 60 .. 309 351 .. 303 361 .. 0.80 5 ! 10.5 0.3 0.0011 0.76 32 151 .. 363 480 .. 344 482 .. 0.83 6 ? 0.3 0.0 1.6 1.1e+03 5 30 .. 534 559 .. 530 562 .. 0.88 7 ! 12.4 0.1 0.0003 0.2 14 99 .. 583 674 .. 572 682 .. 0.77 8 ? -1.7 0.0 6.2 4.3e+03 71 113 .. 697 742 .. 677 745 .. 0.71 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1.3 ARM_TT21_4th 130 lqlAehaaserdyekaiklYkeAL 153 + +A + + r y kai+l++e+L FUN_001881-T1 15 IAVASVLLQIRRYGKAIELFNECL 38 444555555555555555555544 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0085 ARM_TT21_4th 22 YeaalksseqksLrldLAeLllkLkqydkaekvlkqalee.ekskdleslmeev....klllLlakvrks...gkkeealetLkkakelq...arv 106 ++++ + +e+ + L +L+ Lk+y +++ +l++al e++kdl++l ++ ++ ++l + +++ +k a++ L k ++++ r FUN_001881-T1 153 WKEIGNRREEGKTLSLLGDLFNALKEYRRSKLLLERALVIlEEAKDLRELGNTLsclgRVCCILGEYEEAkslQKRALAISVLLKERDAEiadYRN 248 4555555555555556999******************97646788888887776111145577777774311234455778887766654111567 PP ARM_TT21_4th 107 lkrvsveqpdaveeqkkl..aakiclqlAehaaserdy 142 l +v+++ +++ e++k + a ic + ++ + + + y FUN_001881-T1 249 LANVHASMSEVDEAKKCFskALAICKETGDKSGEAKTY 286 77777766665444443211456888877777666655 PP == domain 3 score: 2.4 bits; conditional E-value: 0.34 ARM_TT21_4th 37 dLAeLllkLkqydkaekvlkqaleeekskdleslmeevklllLlakvrk.sgkkeealetLkkakelqa 104 +LA+ + + ++d+a+k ++al+ k++ + + e+k ++ l ++ ++++ea+e ++ a l + FUN_001881-T1 248 NLANVHASMSEVDEAKKCFSKALAICKETGDK--SGEAKTYHVLGGFYRcLNNHNEAIECFRLACALFS 314 68999999999999999999999876554433..56777788888887546778888888777766655 PP == domain 4 score: -0.2 bits; conditional E-value: 2.2 ARM_TT21_4th 18 AinYYeaalksseqksLrldLAeLllkLkqydkaekvlkqale 60 A++ + ++ ++++s +L L++ + ++d+a + ++al FUN_001881-T1 309 ACALFSEVGDRDQESSEYSELGALYCSVGRFDEARQCHEKALV 351 66666777777778888899**************998888775 PP == domain 5 score: 10.5 bits; conditional E-value: 0.0011 ARM_TT21_4th 32 ksLrldLAeLllkLkqydkaekvlkqaleeekskdleslmeevklllLlakvrk.sgkkeealetLkkakelqarvlkrvsveqpdaveeqkklaa 126 + +L +L++ L + ka++ k+al+ + +++sl e++ + la+v++ g+ ++a +ka el++r ++ + ++++ + ++ + FUN_001881-T1 363 GDAYSNLGSLYMALGDPGKAKECYKRALAVDV--ETNSLREQAIDYGHLANVHRvLGDYDKAYLLHEKALELKNRTNENTEEDKES-LCKEYSNLG 455 55567899********************8875..77899999999999*****74799999999999********99988766655.566667788 PP ARM_TT21_4th 127 kiclqlAehaaserdyekaiklYke 151 ++c+ +e++ +++ +++a+ + +e FUN_001881-T1 456 SLCHCRGEYVKAQKYFKRALCIIQE 480 9999999999999999999876655 PP == domain 6 score: 0.3 bits; conditional E-value: 1.6 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a ++++A++Y e++l+ss+ FUN_001881-T1 534 MGKAGQSVGDFSRAMEYHEKVLSSSK 559 7888899999**********999876 PP == domain 7 score: 12.4 bits; conditional E-value: 0.0003 ARM_TT21_4th 14 qYkkAinYYeaalk.......sseqksLrldLAeLllkLkqydkaekvlkqaleeekskdleslmeevklllLlakvr.ksgkkeealetLkka 99 +++kAi+YY+ al ++++ + ++ + +l +y +ae l++al+ + ++++ l+ ++ +l la + ++g++eea+++L ++ FUN_001881-T1 583 DHSKAIEYYQRALAiyqaigeKRGEVVINNNMGTSYLLQWNYREAEGCLNKALSIA--EEIRDLEGKSTVLAHLAALCiSRGNNEEAFSHLLSS 674 677888888888762222111444667999***********************665..689999999999999999987899999999999766 PP == domain 8 score: -1.7 bits; conditional E-value: 6.2 ARM_TT21_4th 71 meevklllLlakvr...ksgkkeealetLkkakelqarvlkrvsve 113 ++v ++ L+a + k+++ ++++L +a+ l + + k++s++ FUN_001881-T1 697 DKTVGFYRLMATMLcsmKETNLALSVSELGRARTLAELMAKQYSMK 742 5667777788877543345667778889999999888888887775 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.74 5.1e+02 37 50 .. 90 103 .. 84 106 .. 0.82 2 ? -1.8 0.1 8.3 5.8e+03 7 51 .. 139 189 .. 136 196 .. 0.62 3 ? 3.2 0.5 0.23 1.6e+02 5 52 .. 217 270 .. 215 272 .. 0.80 4 ? 1.3 0.0 0.92 6.4e+02 31 47 .. 329 345 .. 311 355 .. 0.83 5 ! 12.8 0.0 0.00023 0.16 5 56 .. 337 394 .. 335 400 .. 0.84 6 ? 1.2 0.1 0.94 6.5e+02 5 21 .. 417 433 .. 416 439 .. 0.89 7 ? 5.1 0.1 0.059 41 5 46 .. 462 509 .. 461 514 .. 0.84 8 ? 6.5 0.0 0.022 15 5 55 .. 542 598 .. 540 601 .. 0.62 9 ? 7.2 0.1 0.013 8.7 3 52 .. 580 635 .. 578 640 .. 0.77 10 ? 5.1 0.1 0.059 41 4 44 .. 628 667 .. 623 673 .. 0.80 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.74 TPR_19 37 algrldeAealLaa 50 ++g++d AealL++ FUN_001881-T1 90 QSGNIDGAEALLSK 103 78999999999875 PP == domain 2 score: -1.8 bits; conditional E-value: 8.3 TPR_19 7 ydeAlalLeqalaedPd......naearllLArallalgrldeAealLaal 51 y +A+ +e al++ + + lL+++ al+++ + + lL+++ FUN_001881-T1 139 YSQAKDCFEGALEIWKEignrreEGKTLSLLGDLFNALKEYRRSKLLLERA 189 666666666666663333333335566666777777777777777777765 PP == domain 3 score: 3.2 bits; conditional E-value: 0.23 TPR_19 5 gdydeAlalLeqalae.....dPdnaearl.lLArallalgrldeAealLaalp 52 g+y+eA++l ++ala+ + d a + +LA+++ + ++deA++ +++++ FUN_001881-T1 217 GEYEEAKSLQKRALAIsvllkERDAEIADYrNLANVHASMSEVDEAKKCFSKAL 270 889999999999888877776666555555689999999999999999988776 PP == domain 4 score: 1.3 bits; conditional E-value: 0.92 TPR_19 31 LArallalgrldeAeal 47 L+ ++ gr+deA++ FUN_001881-T1 329 LGALYCSVGRFDEARQC 345 77899999999999985 PP == domain 5 score: 12.8 bits; conditional E-value: 0.00023 TPR_19 5 gdydeAlalLeqal......aedPdnaearllLArallalgrldeAealLaalpaadp 56 g++deA++ e+al + +a+ +L+ +++alg++ +A++ ++++a d FUN_001881-T1 337 GRFDEARQCHEKALvikkeiGDKRGEGDAYSNLGSLYMALGDPGKAKECYKRALAVDV 394 8999999999999955544444777***************************998775 PP == domain 6 score: 1.2 bits; conditional E-value: 0.94 TPR_19 5 gdydeAlalLeqalaed 21 gdyd+A+ l e+al++ FUN_001881-T1 417 GDYDKAYLLHEKALELK 433 9*************975 PP == domain 7 score: 5.1 bits; conditional E-value: 0.059 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 g+y +A++++++al + +++++LA + l lg+ ++ ++ FUN_001881-T1 462 GEYVKAQKYFKRALCIiqemvdRRAEGDILINLASLELSLGEEEKSKQ 509 89************9966666555599999999999999999888765 PP == domain 8 score: 6.5 bits; conditional E-value: 0.022 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaad 55 gd+ +A+++ e++l+ + + + +++++ lg+ ++A++ ++++a + FUN_001881-T1 542 GDFSRAMEYHEKVLSSSKRlgdkrcEGSCYHDTGQCHMSLGDHSKAIEYYQRALAIY 598 556666666666665555444444444444466788888888888888888887765 PP == domain 9 score: 7.2 bits; conditional E-value: 0.013 TPR_19 3 aegdydeAlalLeqalae......dPdnaearllLArallalgrldeAealLaalp 52 gd+ +A++++++ala+ + ++ +++ +l + ++ eAe L++++ FUN_001881-T1 580 SLGDHSKAIEYYQRALAIyqaigeKRGEVVINNNMGTSYLLQWNYREAEGCLNKAL 635 67999999999999998844444455588888899999999999999999998876 PP == domain 10 score: 5.1 bits; conditional E-value: 0.059 TPR_19 4 egdydeAlalLeqalaedPdnaearllLArallalgrldeA 44 eg +++Al++ e++ +++ + +++ LA +++ g+ +eA FUN_001881-T1 628 EGCLNKALSIAEEIRDLE-GKSTVLAHLAALCISRGNNEEA 667 566788999999986665.55556666*************9 PP >> TPR_CcmH_CycH Cytochrome c-type biogenesis protein H TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.013 9.1 29 81 .. 222 274 .. 209 280 .. 0.90 2 ? 6.2 0.0 0.018 12 31 82 .. 304 355 .. 293 362 .. 0.89 3 ? 5.8 0.0 0.023 16 55 86 .. 368 399 .. 358 485 .. 0.85 4 ? -1.2 0.0 3.2 2.2e+03 85 148 .. 489 555 .. 452 560 .. 0.55 5 ? 1.1 0.0 0.62 4.3e+02 57 79 .. 575 597 .. 573 604 .. 0.83 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.013 TPR_CcmH_CycH 29 eeelqdlalgLRtkLqkepddatgWllLGriglslndaetAiqAfekAlklap 81 ++ lq+ al++ L+++ + + L+ ++ s++++++A + f kAl++ FUN_001881-T1 222 AKSLQKRALAISVLLKERDAEIADYRNLANVHASMSEVDEAKKCFSKALAICK 274 56788999****************************************99865 PP == domain 2 score: 6.2 bits; conditional E-value: 0.018 TPR_CcmH_CycH 31 elqdlalgLRtkLqkepddatgWllLGriglslndaetAiqAfekAlklapn 82 e +la +L ++ ++ +++++ LG ++ s+++ ++A q ekAl ++ + FUN_001881-T1 304 ECFRLACALFSEVGDRDQESSEYSELGALYCSVGRFDEARQCHEKALVIKKE 355 6668999999************************************998765 PP == domain 3 score: 5.8 bits; conditional E-value: 0.023 TPR_CcmH_CycH 55 lLGriglslndaetAiqAfekAlklapnntei 86 LG ++++l+d +A + +++Al+++ + +++ FUN_001881-T1 368 NLGSLYMALGDPGKAKECYKRALAVDVETNSL 399 59*********************999887765 PP == domain 4 score: -1.2 bits; conditional E-value: 3.2 TPR_CcmH_CycH 85 eiklsYaqaLmlsgdeedlkkAeelLkkllkqdptnl...ralsllAfnafeqgdyeeAiaaWqkml 148 +i +++a + + g+ee+ k+ +e +++ ++ +++ +++ +++ + gd+++A+++ +k+l FUN_001881-T1 489 DILINLASLELSLGEEEKSKQYRERAHQIAEACGSEIaiqQVYDIMGKAGQSVGDFSRAMEYHEKVL 555 4555555555555555555544444444444333333111566666666677777777777777766 PP == domain 5 score: 1.1 bits; conditional E-value: 0.62 TPR_CcmH_CycH 57 GriglslndaetAiqAfekAlkl 79 G+ ++sl+d ++Ai+ +++Al++ FUN_001881-T1 575 GQCHMSLGDHSKAIEYYQRALAI 597 77889999999999999999876 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.1 9.3 6.5e+03 5 25 .. 168 188 .. 165 190 .. 0.80 2 ? -0.3 0.0 4.4 3.1e+03 6 27 .. 249 270 .. 247 272 .. 0.83 3 ! 9.3 0.1 0.004 2.7 1 27 [. 364 390 .. 364 392 .. 0.92 4 ! 11.2 0.0 0.00097 0.67 6 30 .. 574 598 .. 570 599 .. 0.91 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 9.3 TPR_6 5 klalsylelgdkdeAkaalqr 25 l++++ +l+++ + k +l+r FUN_001881-T1 168 LLGDLFNALKEYRRSKLLLER 188 588899999999999888887 PP == domain 2 score: -0.3 bits; conditional E-value: 4.4 TPR_6 6 lalsylelgdkdeAkaalqrli 27 la + + + deAk+ + + + FUN_001881-T1 249 LANVHASMSEVDEAKKCFSKAL 270 67778888899******99865 PP == domain 3 score: 9.3 bits; conditional E-value: 0.004 TPR_6 1 dAllklalsylelgdkdeAkaalqrli 27 dA+ +l+ +y++lgd +Ak+ ++r + FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAKECYKRAL 390 78889******************9976 PP == domain 4 score: 11.2 bits; conditional E-value: 0.00097 TPR_6 6 lalsylelgdkdeAkaalqrlikkY 30 ++++++ lgd+ +A++++qr ++ Y FUN_001881-T1 574 TGQCHMSLGDHSKAIEYYQRALAIY 598 699*****************99877 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 4.8 3.3e+03 16 34 .] 61 79 .. 59 79 .. 0.88 2 ? 2.6 0.0 0.43 2.9e+02 15 33 .. 205 223 .. 202 224 .. 0.88 3 ? -0.0 0.0 3 2e+03 13 34 .] 283 304 .. 281 304 .. 0.89 4 ? 4.9 0.0 0.081 56 16 34 .] 326 344 .. 321 344 .. 0.91 5 ? 6.2 0.0 0.031 21 14 33 .. 364 383 .. 361 384 .. 0.92 6 ? -0.0 0.0 3 2.1e+03 16 32 .. 406 422 .. 402 423 .. 0.90 7 ? 2.0 0.0 0.64 4.5e+02 16 34 .] 451 469 .. 448 469 .. 0.92 8 ? -1.3 0.0 7.6 5.3e+03 14 34 .] 489 509 .. 488 509 .. 0.87 9 ? -0.8 0.0 5.5 3.8e+03 15 34 .] 570 589 .. 568 589 .. 0.89 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 4.8 TPR_17 16 yynLArlllnnGqleeAlq 34 y L l++ G++++Alq FUN_001881-T1 61 YERLFSLYCLVGDHARALQ 79 7788999**********98 PP == domain 2 score: 2.6 bits; conditional E-value: 0.43 TPR_17 15 ayynLArlllnnGqleeAl 33 + +L+r+ + +G++eeA+ FUN_001881-T1 205 TLSCLGRVCCILGEYEEAK 223 57799************96 PP == domain 3 score: -0.0 bits; conditional E-value: 3 TPR_17 13 adayynLArlllnnGqleeAlq 34 a+ y+ L+ +++ +++++eA++ FUN_001881-T1 283 AKTYHVLGGFYRCLNNHNEAIE 304 678999*************985 PP == domain 4 score: 4.9 bits; conditional E-value: 0.081 TPR_17 16 yynLArlllnnGqleeAlq 34 y L+ l++ G+++eA+q FUN_001881-T1 326 YSELGALYCSVGRFDEARQ 344 889**************98 PP == domain 5 score: 6.2 bits; conditional E-value: 0.031 TPR_17 14 dayynLArlllnnGqleeAl 33 day nL+ l+ +G++ +A+ FUN_001881-T1 364 DAYSNLGSLYMALGDPGKAK 383 89**************9997 PP == domain 6 score: -0.0 bits; conditional E-value: 3 TPR_17 16 yynLArlllnnGqleeA 32 y LA++++ +G++++A FUN_001881-T1 406 YGHLANVHRVLGDYDKA 422 6789***********98 PP == domain 7 score: 2.0 bits; conditional E-value: 0.64 TPR_17 16 yynLArlllnnGqleeAlq 34 y nL+ l + +G++ +A++ FUN_001881-T1 451 YSNLGSLCHCRGEYVKAQK 469 89***************95 PP == domain 8 score: -1.3 bits; conditional E-value: 7.6 TPR_17 14 dayynLArlllnnGqleeAlq 34 d++ nLA l l +G+ e+ +q FUN_001881-T1 489 DILINLASLELSLGEEEKSKQ 509 7899**********9998776 PP == domain 9 score: -0.8 bits; conditional E-value: 5.5 TPR_17 15 ayynLArlllnnGqleeAlq 34 +y++ ++++ +G++ +A++ FUN_001881-T1 570 CYHDTGQCHMSLGDHSKAIE 589 69999**********99985 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.063 43 8 61 .. 222 275 .. 217 283 .. 0.82 2 ? 2.7 0.0 0.27 1.9e+02 30 56 .. 324 350 .. 297 362 .. 0.86 3 ? 5.5 0.0 0.037 25 32 59 .. 366 393 .. 362 405 .. 0.87 4 ? 5.4 0.0 0.039 27 33 58 .. 572 597 .. 569 607 .. 0.86 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.063 TPR_9 8 eedleralavverllllaPddpeerrdrGllyaqlgcleaAladLeaylalapd 61 ++ l++ ++ ll + ++ ++r+ + ++a + + +A +++ ++la++ + FUN_001881-T1 222 AKSLQKRALAISVLLKERDAEIADYRNLANVHASMSEVDEAKKCFSKALAICKE 275 55666666666677777778899**************************99975 PP == domain 2 score: 2.7 bits; conditional E-value: 0.27 TPR_9 30 eerrdrGllyaqlgcleaAladLeayl 56 +e+ + G ly +g++ +A+++ e++l FUN_001881-T1 324 SEYSELGALYCSVGRFDEARQCHEKAL 350 79999***************9977665 PP == domain 3 score: 5.5 bits; conditional E-value: 0.037 TPR_9 32 rrdrGllyaqlgcleaAladLeaylala 59 + + G+ly lg++ +A ++ +++la++ FUN_001881-T1 366 YSNLGSLYMALGDPGKAKECYKRALAVD 393 5678********************9876 PP == domain 4 score: 5.4 bits; conditional E-value: 0.039 TPR_9 33 rdrGllyaqlgcleaAladLeaylal 58 d G+++ lg+ ++A+++ +++la+ FUN_001881-T1 572 HDTGQCHMSLGDHSKAIEYYQRALAI 597 68999999999999999999999976 PP >> TPR_5 Tetratrico peptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.2 0.1 0.0014 0.98 14 66 .. 376 431 .. 366 444 .. 0.79 2 ? -0.8 0.0 3.4 2.4e+03 15 59 .. 462 509 .. 456 534 .. 0.69 3 ! 7.8 0.0 0.0076 5.3 11 101 .. 578 675 .. 569 681 .. 0.64 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.0014 TPR_5 14 vGhedkavplYrraLaaGLagarrrqati...qLassLRnlGeleealaLLraelt 66 G++ ka + Y+raLa ++ r i La R+lG+ ++a L ++ l+ FUN_001881-T1 376 LGDPGKAKECYKRALAVDVETNSLREQAIdygHLANVHRVLGDYDKAYLLHEKALE 431 79***************99988877777734459************9887665443 PP == domain 2 score: -0.8 bits; conditional E-value: 3.4 TPR_5 15 GhedkavplYrraL...aaGLagarrrqatiqLassLRnlGeleeala 59 G+ ka + ++raL ++ ++ + + i Las lGe e++ + FUN_001881-T1 462 GEYVKAQKYFKRALciiQEMVDRRAEGDILINLASLELSLGEEEKSKQ 509 556677778888872222333333345678999999999999988865 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0076 TPR_5 11 rDsvGhedkavplYrraLaaG.Lagarrrqatiq..LassLRnlGeleealaLLr.....aeltrggdelddalaaflaLvLadlgrereavaill 98 + s G++ ka++ Y+raLa g +r+ ++i + s + ea+ L+ ae r ++ + la ++aL++ + g ++ea + ll FUN_001881-T1 578 HMSLGDHSKAIEYYQRALAIYqAIGEKRGEVVINnnMGTSYLLQWNYREAEGCLNkalsiAEEIRDLEGKSTVLAHLAALCI-SRGNNEEAFSHLL 672 5689**************9751458899999997224444332333344444443100003334444555556666666765.6799999999999 PP TPR_5 99 lal 101 ++ FUN_001881-T1 673 SSV 675 886 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 2.6 1.8e+03 11 24 .. 88 101 .. 86 103 .. 0.85 2 ? -0.9 0.0 8.2 5.6e+03 4 21 .. 206 223 .. 204 225 .. 0.81 3 ? 1.1 0.0 1.8 1.3e+03 15 22 .. 337 344 .. 327 345 .. 0.83 4 ? 4.1 0.0 0.19 1.3e+02 3 22 .. 365 384 .. 363 388 .. 0.88 5 ? 2.8 0.0 0.5 3.4e+02 6 20 .. 408 422 .. 406 423 .. 0.91 6 ? -0.3 0.0 5.1 3.5e+03 5 20 .. 452 467 .. 451 468 .. 0.88 7 ? 0.3 0.0 3.3 2.3e+03 4 20 .. 651 667 .. 649 671 .. 0.89 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 2.6 TPR_4 11 llalGdldeArall 24 + + G+ d A+all FUN_001881-T1 88 HSQSGNIDGAEALL 101 5678********98 PP == domain 2 score: -0.9 bits; conditional E-value: 8.2 TPR_4 4 llaLArallalGdldeAr 21 l+ L+r++ lG+++eA FUN_001881-T1 206 LSCLGRVCCILGEYEEAK 223 56788888889*****95 PP == domain 3 score: 1.1 bits; conditional E-value: 1.8 TPR_4 15 GdldeAra 22 G++deAr+ FUN_001881-T1 337 GRFDEARQ 344 ******97 PP == domain 4 score: 4.1 bits; conditional E-value: 0.19 TPR_4 3 allaLArallalGdldeAra 22 a+++L+ ++ alGd+ A + FUN_001881-T1 365 AYSNLGSLYMALGDPGKAKE 384 789************99965 PP == domain 5 score: 2.8 bits; conditional E-value: 0.5 TPR_4 6 aLArallalGdldeA 20 LA ++ lGd+d A FUN_001881-T1 408 HLANVHRVLGDYDKA 422 69***********98 PP == domain 6 score: -0.3 bits; conditional E-value: 5.1 TPR_4 5 laLArallalGdldeA 20 ++L+ +++ +G++ A FUN_001881-T1 452 SNLGSLCHCRGEYVKA 467 68999*******9988 PP == domain 7 score: 0.3 bits; conditional E-value: 3.3 TPR_4 4 llaLArallalGdldeA 20 l+ LA ++ +G+ +eA FUN_001881-T1 651 LAHLAALCISRGNNEEA 667 789**********9999 PP >> Paf67 RNA polymerase I-associated factor PAF67 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.3 0.1 0.0084 5.8 173 202 .. 22 51 .. 7 72 .. 0.73 2 ? 1.9 0.0 0.18 1.3e+02 123 196 .. 206 277 .. 196 290 .. 0.79 3 ? 1.4 0.0 0.26 1.8e+02 126 195 .. 409 481 .. 393 489 .. 0.74 4 ? 4.2 0.0 0.038 26 133 192 .. 541 598 .. 533 609 .. 0.89 5 ? 1.9 0.0 0.19 1.3e+02 132 194 .. 580 640 .. 578 652 .. 0.68 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.0084 Paf67 173 lmlrrYkdAirtfssillyiqrtkqyqsrs 202 l +rrY +Ai+ f+++l+ ++++ ++ s FUN_001881-T1 22 LQIRRYGKAIELFNECLVLLEKHASQMIDS 51 5689******************97743333 PP == domain 2 score: 1.9 bits; conditional E-value: 0.18 Paf67 123 ligllrvhvllGDYtlAlkvlenidlskkalfskvpaahvtlyyyvGfaylmlrrYkdAirtfssillyiqrtk 196 l +l rv ++lG+Y++A k l++ l +++ k a+++ y +++ + + + +A ++fs+ l + t FUN_001881-T1 206 LSCLGRVCCILGEYEEA-KSLQKRALAI-SVLLKERDAEIADYRNLANVHASMSEVDEAKKCFSKALAICKETG 277 66899***********9.7777766665.567777889999999999999999999999999999998887774 PP == domain 3 score: 1.4 bits; conditional E-value: 0.26 Paf67 126 llrvhvllGDYtlAlkvlen.idlskka..lfskvpaahvtlyyyvGfaylmlrrYkdAirtfssillyiqrt 195 l++vh +lGDY++A+ + e+ ++l++++ ++ + y ++G +Y +A + f++ l iq + FUN_001881-T1 409 LANVHRVLGDYDKAYLLHEKaLELKNRTneNTEEDKESLCKEYSNLGSLCHCRGEYVKAQKYFKRALCIIQEM 481 789***********87766436777655224445555556667777766666778888888888888888765 PP == domain 4 score: 4.2 bits; conditional E-value: 0.038 Paf67 133 lGDYtlAlkvlenidlskkalfskvpaahvtlyyyvGfaylmlrrYkdAirtfssillyi 192 +GD++ A++ e++ s+k+l k ++ + y+ +G +++ l ++Ai+ +++ l FUN_001881-T1 541 VGDFSRAMEYHEKVLSSSKRLGDK--RCEGSCYHDTGQCHMSLGDHSKAIEYYQRALAIY 598 7*************9999998776..7999**********************99988765 PP == domain 5 score: 1.9 bits; conditional E-value: 0.19 Paf67 132 llGDYtlAlkvlenidlskkalfskvpaahvtlyyyvGfaylmlrrYkdAirtfssillyiqr 194 lGD ++A++ + +a+ +k +v + ++G +yl+ +Y +A ++++ l + FUN_001881-T1 580 SLGDHSKAIEYYQRALAIYQAIGEK--RGEVVINNNMGTSYLLQWNYREAEGCLNKALSIAEE 640 5666666666665533333333333..335566789*******************99976655 PP >> Sel1 Sel1 repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.078 54 14 34 .. 291 312 .. 283 312 .. 0.80 2 ? 2.1 0.2 0.69 4.8e+02 18 31 .. 376 389 .. 363 391 .. 0.71 3 ? 2.4 0.0 0.54 3.7e+02 18 35 .. 416 433 .. 406 434 .. 0.87 4 ? 2.3 0.1 0.59 4.1e+02 6 31 .. 453 474 .. 451 476 .. 0.78 5 ! 8.7 0.0 0.0056 3.9 10 31 .. 571 594 .. 560 596 .. 0.78 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.078 Sel1 14 Glg.vpkDpekAlewyekAAel 34 G + + ++++A+e++++A++l FUN_001881-T1 291 GFYrCLNNHNEAIECFRLACAL 312 55556779***********985 PP == domain 2 score: 2.1 bits; conditional E-value: 0.69 Sel1 18 pkDpekAlewyekA 31 Dp kA e+y++A FUN_001881-T1 376 LGDPGKAKECYKRA 389 45999*******99 PP == domain 3 score: 2.4 bits; conditional E-value: 0.54 Sel1 18 pkDpekAlewyekAAelG 35 D++kA+ + ekA el FUN_001881-T1 416 LGDYDKAYLLHEKALELK 433 569***********9985 PP == domain 4 score: 2.3 bits; conditional E-value: 0.59 Sel1 6 rLG.ylylyGlgvpkDpekAlewyekA 31 +LG ++ +G+ + kA +++++A FUN_001881-T1 453 NLGsLCHCRGE-----YVKAQKYFKRA 474 78888888887.....77888888887 PP == domain 5 score: 8.7 bits; conditional E-value: 0.0056 Sel1 10 lylyGl..gvpkDpekAlewyekA 31 ++ +G+ + D++kA+e+y++A FUN_001881-T1 571 YHDTGQchMSLGDHSKAIEYYQRA 594 677777544556***********9 PP >> Coatomer_E Coatomer epsilon subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.26 1.8e+02 210 229 .. 212 231 .. 175 280 .. 0.61 2 ? -2.8 0.0 6.8 4.7e+03 206 236 .. 408 438 .. 402 440 .. 0.86 3 ? -1.8 0.0 3.4 2.3e+03 217 252 .. 471 505 .. 461 515 .. 0.57 4 ! 13.2 0.1 8.8e-05 0.061 181 263 .. 589 676 .. 580 681 .. 0.80 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.26 Coatomer_E 210 vslllgryeeAeslLkeaLd 229 v+ lg+yeeA+sl k aL FUN_001881-T1 212 VCCILGEYEEAKSLQKRALA 231 44457889999999888874 PP == domain 2 score: -2.8 bits; conditional E-value: 6.8 Coatomer_E 206 gkAvvslllgryeeAeslLkeaLdkdakdee 236 + A v+ lg+y++A l ++aL+ +++ +e FUN_001881-T1 408 HLANVHRVLGDYDKAYLLHEKALELKNRTNE 438 568899999**************99988766 PP == domain 3 score: -1.8 bits; conditional E-value: 3.4 Coatomer_E 217 yeeAeslLkeaLdkdakdeetLiNlvvaalhlgkda 252 ++ A +++e d+ a + + LiNl + l lg ++ FUN_001881-T1 471 FKRALCIIQEMVDRRA-EGDILINLASLELSLGEEE 505 4445555555555544.3456666666666555553 PP == domain 4 score: 13.2 bits; conditional E-value: 8.8e-05 Coatomer_E 181 ekiqdAyyifqelsekykstplllngkAvvslllgryeeAeslLkeaLdkdakdee......tLiNlvvaalhlgkdaevsernlsqlk 263 e +q A+ i+q + ek ++ n + ll+ +y eAe L++aL ++ + +L+ l ++ g ++e+ ++ ls++k FUN_001881-T1 589 EYYQRALAIYQAIGEK-RGEVVINNNMGTSYLLQWNYREAEGCLNKALSIAEEIRDlegkstVLAHLAALCISRGNNEEAFSHLLSSVK 676 7899************.889999*************************85543322112222788888888888888888888888776 PP >> ANAPC5 Anaphase-promoting complex subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.0053 3.6 43 75 .. 248 280 .. 242 294 .. 0.93 2 ? -2.2 0.0 9.3 6.4e+03 44 74 .. 329 359 .. 324 361 .. 0.88 3 ? 0.0 0.0 1.9 1.3e+03 30 67 .. 480 517 .. 453 531 .. 0.68 4 ? -0.4 0.0 2.4 1.7e+03 25 64 .. 635 674 .. 616 682 .. 0.52 5 ? -0.1 0.0 2.1 1.4e+03 47 71 .. 1112 1136 .. 1104 1142 .. 0.85 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0053 ANAPC5 43 nlailhadfghneeAvkaieeaiklArenkDta 75 nla +ha++++ +eA k ++ a ++ +e +D++ FUN_001881-T1 248 NLANVHASMSEVDEAKKCFSKALAICKETGDKS 280 89*****************************97 PP == domain 2 score: -2.2 bits; conditional E-value: 9.3 ANAPC5 44 lailhadfghneeAvkaieeaiklArenkDt 74 l l+++ g +eA + e a + +e +D+ FUN_001881-T1 329 LGALYCSVGRFDEARQCHEKALVIKKEIGDK 359 67899999*********99999999999887 PP == domain 3 score: 0.0 bits; conditional E-value: 1.9 ANAPC5 30 ssneessyqyallnlailhadfghneeAvkaieeaikl 67 ++ +++ l+nla+l ++g++e++ + e a ++ FUN_001881-T1 480 EMVDRRAEGDILINLASLELSLGEEEKSKQYRERAHQI 517 55455444556899******999999987666555555 PP == domain 4 score: -0.4 bits; conditional E-value: 2.4 ANAPC5 25 FDytlssneessyqyallnlailhadfghneeAvkaieea 64 ++ + ++ + + l +la l + g+neeA + + + FUN_001881-T1 635 LSIAEEIRDLEGKSTVLAHLAALCISRGNNEEAFSHLLSS 674 3333333333333444556666666666666666665555 PP == domain 5 score: -0.1 bits; conditional E-value: 2.1 ANAPC5 47 lhadfghneeAvkaieeaiklAren 71 ++ ++ + ++A ++++ea kl re FUN_001881-T1 1112 FYESLVCGKSASESLHEAMKLMRED 1136 5667789999*************96 PP >> Wzy_C_2 Virulence factor membrane-bound polymerase, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.063 44 147 178 .. 59 90 .. 53 93 .. 0.92 2 ? 2.2 0.0 0.33 2.3e+02 145 174 .. 362 391 .. 324 397 .. 0.80 3 ? -2.4 0.0 8.2 5.6e+03 142 172 .. 484 514 .. 466 516 .. 0.80 4 ? 4.2 0.0 0.074 51 133 179 .. 555 601 .. 543 612 .. 0.80 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.063 Wzy_C_2 147 avierlilslallGrpeeAqqilararalfpe 178 v+erl ++ l G+ ++A q ++a a++ + FUN_001881-T1 59 LVYERLFSLYCLVGDHARALQSGEKAHAMHSQ 90 69*************************99876 PP == domain 2 score: 2.2 bits; conditional E-value: 0.33 Wzy_C_2 145 epavierlilslallGrpeeAqqilarara 174 e +++l ++++lG+p +A++ ++ra a FUN_001881-T1 362 EGDAYSNLGSLYMALGDPGKAKECYKRALA 391 566799999*****************9986 PP == domain 3 score: -2.4 bits; conditional E-value: 8.2 Wzy_C_2 142 lsPepavierlilslallGrpeeAqqilara 172 ++ e ++ +l+ + lG +e+ +q+++ra FUN_001881-T1 484 RRAEGDILINLASLELSLGEEEKSKQYRERA 514 55566677789999999***********998 PP == domain 4 score: 4.2 bits; conditional E-value: 0.074 Wzy_C_2 133 lalaekllhlsPepavierlilslallGrpeeAqqilararalfpee 179 l+ +++l + e + ++ + ++ + lG+ ++A ++++ra a + + FUN_001881-T1 555 LSSSKRLGDKRCEGSCYHDTGQCHMSLGDHSKAIEYYQRALAIYQAI 601 5556666666667788999999**********************875 PP >> DUF7380 Domain of unknown function (DUF7380) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 2.9 2e+03 152 174 .. 140 162 .. 128 177 .. 0.69 2 ? 3.8 0.1 0.093 64 137 174 .. 246 282 .. 223 285 .. 0.85 3 ? -0.5 0.0 1.9 1.3e+03 151 174 .. 339 362 .. 310 365 .. 0.86 4 ? -0.3 0.0 1.7 1.2e+03 149 174 .. 462 487 .. 421 490 .. 0.70 5 ? 6.0 0.0 0.02 14 149 175 .. 582 608 .. 557 610 .. 0.82 6 ? -2.6 0.0 8.3 5.7e+03 154 171 .. 627 644 .. 620 669 .. 0.72 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2.9 DUF7380 152 vdalkrleRAlqlaaqlgkrkee 174 ++a +++e Al++ +++g r+ee FUN_001881-T1 140 SQAKDCFEGALEIWKEIGNRREE 162 45667777777777777777665 PP == domain 2 score: 3.8 bits; conditional E-value: 0.093 DUF7380 137 YlesaeeledgseewvdalkrleRAlqlaaqlgkrkee 174 Y + a+ + + e +a k++++Al ++++ g+++ e FUN_001881-T1 246 YRNLANVHASM-SEVDEAKKCFSKALAICKETGDKSGE 282 77777777776.778899***************99876 PP == domain 3 score: -0.5 bits; conditional E-value: 1.9 DUF7380 151 wvdalkrleRAlqlaaqlgkrkee 174 + +a+++ e+Al + +++g+++ e FUN_001881-T1 339 FDEARQCHEKALVIKKEIGDKRGE 362 557899**************9987 PP == domain 4 score: -0.3 bits; conditional E-value: 1.7 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkee 174 e v+a k+++RAl + +++ +r+ e FUN_001881-T1 462 GEYVKAQKYFKRALCIIQEMVDRRAE 487 45678888899999888887777665 PP == domain 5 score: 6.0 bits; conditional E-value: 0.02 DUF7380 149 eewvdalkrleRAlqlaaqlgkrkeep 175 +++a+++++RAl + +++g+++ e+ FUN_001881-T1 582 GDHSKAIEYYQRALAIYQAIGEKRGEV 608 567899****************99876 PP == domain 6 score: -2.6 bits; conditional E-value: 8.3 DUF7380 154 alkrleRAlqlaaqlgkr 171 a +l +Al++a ++++ FUN_001881-T1 627 AEGCLNKALSIAEEIRDL 644 455777777777777764 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.84 5.8e+02 8 25 .. 19 36 .. 16 39 .. 0.83 2 ? 4.1 0.0 0.13 92 10 26 .. 88 104 .. 86 107 .. 0.91 3 ? -0.9 0.0 5.5 3.8e+03 15 26 .. 145 156 .. 143 160 .. 0.83 4 ? 4.6 0.1 0.095 66 4 22 .. 207 225 .. 205 230 .. 0.84 5 ? 1.6 0.0 0.83 5.7e+02 4 25 .. 247 268 .. 246 270 .. 0.86 6 ? -1.7 0.0 9.9 6.8e+03 9 24 .. 292 307 .. 285 308 .. 0.74 7 ? 4.3 0.1 0.12 80 9 25 .. 332 348 .. 329 350 .. 0.88 8 ? 3.4 0.0 0.22 1.5e+02 2 25 .. 365 388 .. 364 391 .. 0.91 9 ? -0.2 0.0 3.1 2.1e+03 5 25 .. 408 428 .. 405 433 .. 0.77 10 ? -0.1 0.0 3 2.1e+03 14 25 .. 462 473 .. 451 485 .. 0.58 11 ? -0.3 0.0 3.4 2.4e+03 9 25 .. 577 593 .. 576 595 .. 0.86 12 ? -0.9 0.1 5.4 3.7e+03 5 25 .. 1115 1135 .. 1112 1135 .. 0.80 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.84 PPR 8 sgycknGkleeAlelfke 25 s++ + +++ +A+elf+e FUN_001881-T1 19 SVLLQIRRYGKAIELFNE 36 5677788999******99 PP == domain 2 score: 4.1 bits; conditional E-value: 0.13 PPR 10 ycknGkleeAlelfkeM 26 ++++G+++ A+ l+ +M FUN_001881-T1 88 HSQSGNIDGAEALLSKM 104 689************** PP == domain 3 score: -0.9 bits; conditional E-value: 5.5 PPR 15 kleeAlelfkeM 26 ++e Ale++ke+ FUN_001881-T1 145 CFEGALEIWKEI 156 6899******97 PP == domain 4 score: 4.6 bits; conditional E-value: 0.095 PPR 4 nslIsgycknGkleeAlel 22 ++l +++c G++eeA++l FUN_001881-T1 207 SCLGRVCCILGEYEEAKSL 225 567789**********998 PP == domain 5 score: 1.6 bits; conditional E-value: 0.83 PPR 4 nslIsgycknGkleeAlelfke 25 l +++++ +++eA+++f + FUN_001881-T1 247 RNLANVHASMSEVDEAKKCFSK 268 567899999**********986 PP == domain 6 score: -1.7 bits; conditional E-value: 9.9 PPR 9 gycknGkleeAlelfk 24 y +++ eA+e+f+ FUN_001881-T1 292 FYRCLNNHNEAIECFR 307 567788999****997 PP == domain 7 score: 4.3 bits; conditional E-value: 0.12 PPR 9 gycknGkleeAlelfke 25 yc+ G+++eA +++++ FUN_001881-T1 332 LYCSVGRFDEARQCHEK 348 5**********998875 PP == domain 8 score: 3.4 bits; conditional E-value: 0.22 PPR 2 tynslIsgycknGkleeAlelfke 25 +y+ l s y G++ +A+e++k+ FUN_001881-T1 365 AYSNLGSLYMALGDPGKAKECYKR 388 5999999**************997 PP == domain 9 score: -0.2 bits; conditional E-value: 3.1 PPR 5 slIsgycknGkleeAlelfke 25 l +++ G++++A l+++ FUN_001881-T1 408 HLANVHRVLGDYDKAYLLHEK 428 566777789******999987 PP == domain 10 score: -0.1 bits; conditional E-value: 3 PPR 14 GkleeAlelfke 25 G++ +A ++fk+ FUN_001881-T1 462 GEYVKAQKYFKR 473 555566665554 PP == domain 11 score: -0.3 bits; conditional E-value: 3.4 PPR 9 gycknGkleeAlelfke 25 ++ + G++++A+e++++ FUN_001881-T1 577 CHMSLGDHSKAIEYYQR 593 67789********9986 PP == domain 12 score: -0.9 bits; conditional E-value: 5.4 PPR 5 slIsgycknGkleeAlelfke 25 sl+ g + + l+eA++l++e FUN_001881-T1 1115 SLVCGKSASESLHEAMKLMRE 1135 7777888888999****9987 PP >> DUF3856 Domain of Unknown Function (DUF3856) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.73 5e+02 51 94 .. 54 97 .. 9 107 .. 0.74 2 ? 3.6 0.5 0.12 84 22 75 .. 216 270 .. 197 315 .. 0.78 3 ? 3.0 0.0 0.19 1.3e+02 59 86 .. 327 354 .. 321 388 .. 0.78 4 ? 9.7 0.2 0.0016 1.1 54 132 .. 402 480 .. 363 490 .. 0.78 5 ? 0.6 0.1 1 7.2e+02 45 83 .. 558 596 .. 492 614 .. 0.51 6 ? 1.6 0.0 0.51 3.5e+02 70 142 .. 623 690 .. 573 691 .. 0.60 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.73 DUF3856 51 eGfdalchaglsealvklgrfeealhsaekalryfnrrGelnqd 94 + f +l + l ++ +g + al+s eka + G+++ FUN_001881-T1 54 SAFTTLVYERLFSLYCLVGDHARALQSGEKAHAMHSQSGNIDGA 97 56888888889999999999999999999998888888877655 PP == domain 2 score: 3.6 bits; conditional E-value: 0.12 DUF3856 22 ageyeeaaescrralevsrtipaeea..fdyeGfdalchaglsealvklgrfeeal 75 geyeea +ral +s + +a dy + a ha++se + f +al FUN_001881-T1 216 LGEYEEAKSLQKRALAISVLLKERDAeiADYRNL-ANVHASMSEVDEAKKCFSKAL 270 489***************9998765522566665.556777777766666666665 PP == domain 3 score: 3.0 bits; conditional E-value: 0.19 DUF3856 59 aglsealvklgrfeealhsaekalryfn 86 + l ++ +grf+ea + ekal FUN_001881-T1 327 SELGALYCSVGRFDEARQCHEKALVIKK 354 567788999**************97544 PP == domain 4 score: 9.7 bits; conditional E-value: 0.0016 DUF3856 54 dalchaglsealvklgrfeealhsaekalryfnrrGelnqdeGklwiaavfsralaleg.lGrkeealkafkkagemiae 132 +a+ + l++ + lg +++a ekal+ nr e n +e k ++ +s+ +l G+ +a k fk+a +i+e FUN_001881-T1 402 QAIDYGHLANVHRVLGDYDKAYLLHEKALELKNRTNE-NTEEDKESLCKEYSNLGSLCHcRGEYVKAQKYFKRALCIIQE 480 3555678999999******************999887.88999*********99988551699999******99888776 PP == domain 5 score: 0.6 bits; conditional E-value: 1 DUF3856 45 eeafdyeGfdalchaglsealvklgrfeealhsaekalr 83 + + + + c+ + ++ lg + +a++ ++al FUN_001881-T1 558 SKRLGDKRCEGSCYHDTGQCHMSLGDHSKAIEYYQRALA 596 333333333333333333333333333333333333333 PP == domain 6 score: 1.6 bits; conditional E-value: 0.51 DUF3856 70 rfeealhsaekalryfnrrGelnqdeGklwiaavfsralaleglGrkeealkafkkagemiaerkGelpgkee 142 ++ ea +kal e++ eGk + a al + G++eea +++ +++i++ +G l + e+ FUN_001881-T1 623 NYREAEGCLNKALSI---AEEIRDLEGKSTVLAHL-AALCI-SRGNNEEAFSHLLSSVKIIDDMRGSLGDSER 690 444444444455443...33556667775554432.23333.4688888888888888888888888888775 PP >> TPR_21 Tetratricopeptide repeat-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.36 2.5e+02 114 173 .. 249 310 .. 221 321 .. 0.68 2 ? 0.7 0.0 0.74 5.1e+02 153 173 .. 330 350 .. 319 362 .. 0.86 3 ? 5.6 0.1 0.023 16 152 176 .. 369 393 .. 341 406 .. 0.80 4 ? -0.7 0.0 2 1.4e+03 153 176 .. 575 598 .. 563 609 .. 0.84 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.36 TPR_21 114 varlr..LarvllaekkydeALktLeakkdeafaalvaelkGDilvaqgkldeAraAYqaAl 173 +a++ +++v a+k + +AL+ +++ d++ +a++ + G ++ ++ +eA + ++ A FUN_001881-T1 249 LANVHasMSEVDEAKKCFSKALAICKETGDKSGEAKTYHVLGGFYRCLNNHNEAIECFRLAC 310 44432225566666666777777777777777777777777777777777777777666665 PP == domain 2 score: 0.7 bits; conditional E-value: 0.74 TPR_21 153 GDilvaqgkldeAraAYqaAl 173 G ++ + g++deAr+ ++Al FUN_001881-T1 330 GALYCSVGRFDEARQCHEKAL 350 8899***************98 PP == domain 3 score: 5.6 bits; conditional E-value: 0.023 TPR_21 152 kGDilvaqgkldeAraAYqaAlaal 176 G +++a g+ +A++ Y++Ala FUN_001881-T1 369 LGSLYMALGDPGKAKECYKRALAVD 393 599******************9855 PP == domain 4 score: -0.7 bits; conditional E-value: 2 TPR_21 153 GDilvaqgkldeAraAYqaAlaal 176 G +++ g+ +A + Yq+Ala FUN_001881-T1 575 GQCHMSLGDHSKAIEYYQRALAIY 598 7888999*************9855 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.3 0.11 73 58 98 .. 223 264 .. 188 276 .. 0.90 2 ? 6.0 0.0 0.014 10 152 186 .. 369 403 .. 330 439 .. 0.86 3 ? 0.5 0.0 0.67 4.6e+02 226 243 .. 579 596 .. 574 600 .. 0.72 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.11 TPR_15 58 qqeeeallAyrrllatgkaraedyerlial.lresrpkeaar 98 ++ ++ +lA ++ll+ ++a+ dy +l + ++s+ +ea + FUN_001881-T1 223 KSLQKRALAISVLLKERDAEIADYRNLANVhASMSEVDEAKK 264 67788899********************99899999999876 PP == domain 2 score: 6.0 bits; conditional E-value: 0.014 TPR_15 152 raelerqegekkaAleayreAltlaPgdselragl 186 ++ l+ + g++ +A e+y++Al+++ + ++lr++ FUN_001881-T1 369 LGSLYMALGDPGKAKECYKRALAVDVETNSLREQA 403 567888999********************999976 PP == domain 3 score: 0.5 bits; conditional E-value: 0.67 TPR_15 226 lllgqnrkALpyfrkkaa 243 + lg+ +kA +y+++ +a FUN_001881-T1 579 MSLGDHSKAIEYYQRALA 596 678888888888887655 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.5 0.024 17 56 100 .. 225 269 .. 218 273 .. 0.88 2 ? 2.8 0.0 0.17 1.1e+02 65 100 .. 314 349 .. 300 354 .. 0.84 3 ? 2.4 0.0 0.22 1.5e+02 59 100 .. 348 389 .. 336 404 .. 0.84 4 ? 3.4 0.0 0.11 73 78 144 .. 612 676 .. 590 696 .. 0.77 5 ? -2.3 0.0 6 4.1e+03 53 80 .. 717 744 .. 712 749 .. 0.81 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.024 TPR_COPA_B 56 lqlgklevalelakeadseqkwkqlgdlalkkgklklaeecleka 100 lq + l ++ l +++ + + +++l+++ + ++++ a++c++ka FUN_001881-T1 225 LQKRALAISVLLKERDAEIADYRNLANVHASMSEVDEAKKCFSKA 269 67778888888888889999***********************98 PP == domain 2 score: 2.8 bits; conditional E-value: 0.17 TPR_COPA_B 65 lelakeadseqkwkqlgdlalkkgklklaeecleka 100 e+ +++++++ + +lg l ++ g+++ a++c eka FUN_001881-T1 314 SEVGDRDQESSEYSELGALYCSVGRFDEARQCHEKA 349 46777889999**********************998 PP == domain 3 score: 2.4 bits; conditional E-value: 0.22 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecleka 100 + l + +e+ ++ + + + +lg l ++ g+ a+ec+++a FUN_001881-T1 348 KALVIKKEIGDKRGEGDAYSNLGSLYMALGDPGKAKECYKRA 389 4578889999999999************************98 PP == domain 4 score: 3.4 bits; conditional E-value: 0.11 TPR_COPA_B 78 kqlgdlalkkgklklaeeclekakdlsglLLlatssgnaegleklaekaeekgknniaFlalfllgk 144 +++g l +++++ ae cl+ka + + g+++ l++la+ + ++g+n+ aF l++ k FUN_001881-T1 612 NNMGTSYLLQWNYREAEGCLNKALSIAEE--IRDLEGKSTVLAHLAALCISRGNNEEAFSHLLSSVK 676 678889999**************999887..5889999******************99998776543 PP == domain 5 score: -2.3 bits; conditional E-value: 6 TPR_COPA_B 53 dLalqlgklevalelakeadseqkwkql 80 +Lal++++l a++la+ + ++ k+l FUN_001881-T1 717 NLALSVSELGRARTLAELMAKQYSMKNL 744 6999999999999999988777776665 PP >> HEAT_Nup120 Nucleoporin Nup120, HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.2 0.31 2.2e+02 34 137 .. 19 110 .. 16 116 .. 0.62 2 ? -1.0 0.0 2.9 2e+03 87 135 .. 125 176 .. 110 181 .. 0.81 3 ? 6.9 0.2 0.01 7.2 65 144 .. 245 342 .. 208 348 .. 0.60 4 ? -0.7 0.0 2.2 1.5e+03 33 56 .. 370 394 .. 366 438 .. 0.60 5 ? -1.4 0.0 3.8 2.6e+03 34 56 .. 456 478 .. 453 512 .. 0.72 6 ? -1.0 0.0 2.8 1.9e+03 27 52 .. 568 594 .. 546 628 .. 0.78 7 ? -0.7 0.0 2.2 1.5e+03 109 150 .. 632 673 .. 584 676 .. 0.80 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.31 HEAT_Nup120 34 rllLalgefdeAaelFkkaayglsgkdsaesdedseglldvlepnalnsglpkYYahvasLfekakaysyvaefarlAlqfkqkapdeddrsells 129 +lL+ +++ +A elF++ + l +++s+ d++++++ Y+++ sL+ + + +++ + A +++++ + d ++lls FUN_001881-T1 19 SVLLQIRRYGKAIELFNECLVLLEKHASQMIDSRRSAFTT------------LVYERLFSLYCLVGDHARALQSGEKAHAMHSQSGNIDGAEALLS 102 5677777777777777777777733333333333333333............34777777777777777777777777777555555555778888 PP HEAT_Nup120 130 rlfkaala 137 ++f+ + + FUN_001881-T1 103 KMFHLYFS 110 88887766 PP == domain 2 score: -1.0 bits; conditional E-value: 2.9 HEAT_Nup120 87 YYahvasLfekakaysyvaefarlAlqf...kqkapdeddrsellsrlfkaa 135 + ++ + f++ ys++ ++ + Al++ + +e ++ +ll lf+a FUN_001881-T1 125 FLVRIGTKFKSDFNYSQAKDCFEGALEIwkeIGNRREEGKTLSLLGDLFNAL 176 5566777889999999999999999999987777777777899999999986 PP == domain 3 score: 6.9 bits; conditional E-value: 0.01 HEAT_Nup120 65 d...............ed...seglldvlepnalnsglpkYYahvasLfekakaysyvaefarlAlqfkqkapdeddrsellsrlfkaalalgrfe 142 d e ++ l++ + + +sg++k Y+ + +++ + +++++e+ rlA ++ d d++s+ s+l ++++grf+ FUN_001881-T1 245 DyrnlanvhasmsevdEAkkcFSKALAICKETGDKSGEAKTYHVLGGFYRCLNNHNEAIECFRLACALFSEVGDRDQESSEYSELGALYCSVGRFD 340 233333333333333211223344444443444678889989888888999999999999999999996666666667788999999999999999 PP HEAT_Nup120 143 eA 144 eA FUN_001881-T1 341 EA 342 98 PP == domain 4 score: -0.7 bits; conditional E-value: 2.2 HEAT_Nup120 33 GrllLalgefdeAaelFkka.aygl 56 G l++alg++ +A+e+ k+a a+ + FUN_001881-T1 370 GSLYMALGDPGKAKECYKRAlAVDV 394 6778888888888888776523444 PP == domain 5 score: -1.4 bits; conditional E-value: 3.8 HEAT_Nup120 34 rllLalgefdeAaelFkkaaygl 56 l+ +ge+ +A+++Fk+a + FUN_001881-T1 456 SLCHCRGEYVKAQKYFKRALCII 478 55666899********9985555 PP == domain 6 score: -1.0 bits; conditional E-value: 2.8 HEAT_Nup120 27 wstYv.kGrllLalgefdeAaelFkka 52 +s+Y G+++++lg++++A e+ ++a FUN_001881-T1 568 GSCYHdTGQCHMSLGDHSKAIEYYQRA 594 555542588999999999999988876 PP == domain 7 score: -0.7 bits; conditional E-value: 2.2 HEAT_Nup120 109 rlAlqfkqkapdeddrsellsrlfkaalalgrfeeAYsaLls 150 + Al+++++ d + +s +l +l +++ g+ eeA+s Lls FUN_001881-T1 632 NKALSIAEEIRDLEGKSTVLAHLAALCISRGNNEEAFSHLLS 673 567777444444444889999999999999999999988875 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 1.1 7.4e+02 30 55 .. 18 44 .. 2 49 .. 0.69 2 ? 3.6 0.5 0.18 1.2e+02 40 76 .. 187 223 .. 175 229 .. 0.83 3 ? 2.1 0.2 0.49 3.4e+02 18 47 .. 278 307 .. 255 349 .. 0.69 4 ? 5.3 0.2 0.051 35 29 54 .. 409 435 .. 381 441 .. 0.80 5 ? 8.3 0.1 0.0058 4 6 49 .. 545 594 .. 541 600 .. 0.73 6 ? 1.9 0.1 0.59 4.1e+02 39 79 .. 631 671 .. 614 674 .. 0.62 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 1.1 ANAPC3 30 AqclflngqykrAyellrka.klneks 55 A +l++ +y +A+el++++ l ek+ FUN_001881-T1 18 ASVLLQIRRYGKAIELFNEClVLLEKH 44 677777777777777777775555555 PP == domain 2 score: 3.6 bits; conditional E-value: 0.18 ANAPC3 40 krAyellrkaklnekslgcryllAqcllkLkkykeAl 76 +rA+ +l++ak + + + +l++++ L++y+eA FUN_001881-T1 187 ERALVILEEAKDLRELGNTLSCLGRVCCILGEYEEAK 223 7899999999666666689999*************95 PP == domain 3 score: 2.1 bits; conditional E-value: 0.49 ANAPC3 18 aepespedayllAqclflngqykrAyellr 47 +++ +++ + l+ ++ ++++++A+e +r FUN_001881-T1 278 DKSGEAKTYHVLGGFYRCLNNHNEAIECFR 307 555555556666777777777777776654 PP == domain 4 score: 5.3 bits; conditional E-value: 0.051 ANAPC3 29 lAqclflngqykrAyellrka.klnek 54 lA++++ +g+y++Ay l +ka +l+++ FUN_001881-T1 409 LANVHRVLGDYDKAYLLHEKAlELKNR 435 79*************999999666554 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0058 ANAPC3 6 knAiflaerlla....aepespedayll..AqclflngqykrAyellrka 49 + A+ + e++l+ +++e +++ +qc+ ++g++ +A+e+ ++a FUN_001881-T1 545 SRAMEYHEKVLSsskrLGDKRCEGSCYHdtGQCHMSLGDHSKAIEYYQRA 594 567777778884223344556666777666****************9998 PP == domain 6 score: 1.9 bits; conditional E-value: 0.59 ANAPC3 39 ykrAyellrka.klnekslgcryllAqcllkLkkykeAldaL 79 ++A+ + ++ +l++ks+ + lA ++ ++ +eA ++L FUN_001881-T1 631 LNKALSIAEEIrDLEGKSTV-LAHLAALCISRGNNEEAFSHL 671 46677777777666666654.444444556666666666665 PP >> NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 8.1 5.6e+03 22 36 .. 217 231 .. 213 243 .. 0.84 2 ? -0.5 0.0 3.2 2.2e+03 24 41 .. 299 316 .. 295 329 .. 0.85 3 ? 3.9 0.0 0.13 89 20 35 .. 335 350 .. 330 356 .. 0.85 4 ? 8.1 0.0 0.0064 4.4 24 47 .. 1112 1135 .. 1105 1142 .. 0.88 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 8.1 NRBF2_MIT 22 Gkyeeaischkkaaa 36 G yeea s k+a a FUN_001881-T1 217 GEYEEAKSLQKRALA 231 99******9999865 PP == domain 2 score: -0.5 bits; conditional E-value: 3.2 NRBF2_MIT 24 yeeaischkkaaaylsea 41 ++eai c + a+a +se FUN_001881-T1 299 HNEAIECFRLACALFSEV 316 78**********999985 PP == domain 3 score: 3.9 bits; conditional E-value: 0.13 NRBF2_MIT 20 aaGkyeeaischkkaa 35 + G+++ea ch+ka FUN_001881-T1 335 SVGRFDEARQCHEKAL 350 579***********95 PP == domain 4 score: 8.1 bits; conditional E-value: 0.0064 NRBF2_MIT 24 yeeaischkkaaaylseamkltks 47 + e++ c k a++ l eamkl + FUN_001881-T1 1112 FYESLVCGKSASESLHEAMKLMRE 1135 67999****************875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1159 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 789 (0.0308867); expected 510.9 (0.02) Passed bias filter: 649 (0.0254061); expected 510.9 (0.02) Passed Vit filter: 88 (0.0034449); expected 25.5 (0.001) Passed Fwd filter: 38 (0.00148757); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 37 [number of targets reported over threshold] # CPU time: 0.57u 0.39s 00:00:00.96 Elapsed: 00:00:00.45 # Mc/sec: 10334.08 // Query: FUN_001882-T1 [L=101] Description: FUN_001882 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-07 30.1 0.1 6.5e-07 30.0 0.1 1.3 1 Rdx Rdx family ------ inclusion threshold ------ 0.061 13.8 0.1 0.11 12.9 0.1 1.5 2 DUF6991 Domain of unknown function (DUF6991) Domain annotation for each model (and alignments): >> Rdx Rdx family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.0 0.1 5.1e-11 6.5e-07 42 72 .. 48 78 .. 13 80 .. 0.92 Alignments for each domain: == domain 1 score: 30.0 bits; conditional E-value: 5.1e-11 Rdx 42 GaFeVtldgelvwskkeeggfpeakelkqli 72 +FeV+++g+lv+sk+e+ggfp ke++q + FUN_001882-T1 48 ASFEVKVNGKLVFSKLEKGGFPVFKEVVQVV 78 58**************************988 PP >> DUF6991 Domain of unknown function (DUF6991) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 1.1 1.4e+04 24 30 .. 5 11 .. 4 18 .. 0.56 2 ? 12.9 0.1 9e-06 0.11 27 43 .. 51 67 .. 42 88 .. 0.84 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 1.1 DUF6991 24 LGenvKv 30 LG+n+ FUN_001882-T1 5 LGRNIVS 11 5666544 PP == domain 2 score: 12.9 bits; conditional E-value: 9e-06 DUF6991 27 nvKvvgkivfsKlEaGk 43 vKv gk+vfsKlE+G FUN_001882-T1 51 EVKVNGKLVFSKLEKGG 67 69*************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 532 (0.020826); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1027.26 // Query: FUN_001883-T1 [L=208] Description: FUN_001883 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-20 73.2 0.0 3.1e-20 72.7 0.0 1.2 1 ODC_AZ Ornithine decarboxylase antizyme Domain annotation for each model (and alignments): >> ODC_AZ Ornithine decarboxylase antizyme # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 72.7 0.0 1.2e-24 3.1e-20 25 113 .. 124 206 .. 116 207 .. 0.92 Alignments for each domain: == domain 1 score: 72.7 bits; conditional E-value: 1.2e-24 ODC_AZ 25 kertlfvfldesvlgedlKegLvaLlElAeeklkcsevvvcldrsredrakelvrtLqwvGFelvtldawavaeeldvtsekwlflgme 113 ++ l+v+++++ l+ ++Ke++v+LlE+Aee+lkc++v++ l ++r+dra+ l+rt++++GFe+vt+++ ++ ++ +++f+++ FUN_001883-T1 124 QNGRLYVEVKDGELPPGSKECFVSLLEYAEEHLKCEHVFIGLLKERPDRAS-LMRTFMFMGFETVTPGHKLCP-----NNGNFIFMVYT 206 6789**********************************************9.*****************9976.....67788899886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 570 (0.0223136); expected 510.9 (0.02) Passed bias filter: 533 (0.0208651); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2086.78 // Query: FUN_001884-T1 [L=219] Description: FUN_001884 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-64 218.1 0.0 2e-64 217.9 0.0 1.0 1 Trypsin Trypsin 0.00053 21.2 0.1 0.0026 19.0 0.1 1.9 1 Trypsin_2 Trypsin-like peptidase domain ------ inclusion threshold ------ 0.054 14.4 0.0 0.083 13.8 0.0 1.2 1 DUF1986 Domain of unknown function (DUF1986) Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 217.9 0.0 2.4e-68 2e-64 23 220 .] 6 213 .. 1 213 [. 0.94 Alignments for each domain: == domain 1 score: 217.9 bits; conditional E-value: 2.4e-68 Trypsin 23 gkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegseqklkvekvivhpnynsdtldnDiallklkspvtlgdavrpiclpaasssl 116 g++fCGGsli+++wvlTAaHCv + +ss+kv+lg+h ++++e+++q+++v+k++ hp+y+s+t++nD+al+kl++p lg+ v +cl ++s +l FUN_001884-T1 6 GGQFCGGSLIHPQWVLTAAHCVMSesESSFKVWLGAHRREEKEDTTQEFSVAKIVRHPKYSSSTMENDMALIKLDRPSILGPGVGLVCLGDDSHHL 101 368*********************9******************************************************************66666 PP Trypsin 117 ...avgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsayggkvtdnmicagak.ggkdacqGDSGGPlvcsdg...eliGivswgkgcasg 204 + +cl+sGwG+ +++g +++tlqev vp+vs +ec + yg+++ ++m+cag+k ggkd+cqGDSGGPlvc+ +l G +s+gkgca++ FUN_001884-T1 102 pldDLNNQCLISGWGTLSSGGsQPNTLQEVMVPLVSPSECGRVYGQTMHSSMLCAGFKsGGKDSCQGDSGGPLVCQFSgkyFLEGATSFGKGCADP 197 22456789**************************************************999***************9999**************** PP Trypsin 205 nkpgvytrvssyadwi 220 + +gvy++v +++++i FUN_001884-T1 198 EAYGVYAKVRDLRQFI 213 *********9998876 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.1 3.1e-07 0.0026 3 76 .. 12 98 .. 10 181 .. 0.55 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 3.1e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav....vaekvsvaladgreyaatvvaadp.......elDlallkv...sedgaglpplplgdsa 76 G ++ ++ vlT+aH+v ++ e+ a+++++ + +e+++ + ++p e D+al+k+ s g g++ + lgd++ FUN_001884-T1 12 GSLIHPQW-VLTAAHCVMSESESSFkvwlGAHRREEKEDTTQEFSVAKIVRHPkyssstmENDMALIKLdrpSILGPGVGLVCLGDDS 98 66788887.********888888886677555555555555555555444444688887777*******7775555555555566633 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 9.8e-06 0.083 10 110 .. 5 111 .. 2 115 .. 0.70 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 9.8e-06 DUF1986 10 eGdlicsGvlidkswvlvsesclsdvdlehsyvsvvlGgaktkksvkgpye....qivrvdafk.dvpksevvllhlkskvsfsrhvlPtfvpesr 100 +G +c G li +wvl c+++ + s v lG+++ + + e +ivr + + ++ l+ l+++ v + + + + FUN_001884-T1 5 DGGQFCGGSLIHPQWVLTAAHCVMSESE--SSFKVWLGAHRREEKEDTTQEfsvaKIVRHPKYSsSTMENDMALIKLDRPSILGPGVGLVCLGDDS 98 89999*****************987765..778999999988776655544212245555444314667788889999888888888888888877 PP DUF1986 101 nen...ekdakcv 110 +++ + +++c+ FUN_001884-T1 99 HHLpldDLNNQCL 111 7762213345665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 378 (0.0147974); expected 510.9 (0.02) Passed bias filter: 347 (0.0135839); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2216.89 // Query: FUN_001884-T2 [L=289] Description: FUN_001884 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-70 237.9 0.1 1.8e-70 237.7 0.1 1.0 1 Trypsin Trypsin 0.0005 20.9 0.0 0.00074 20.4 0.0 1.2 1 DUF1986 Domain of unknown function (DUF1986) 0.0011 20.3 0.1 0.0054 18.0 0.1 2.0 1 Trypsin_2 Trypsin-like peptidase domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 237.7 0.1 2.1e-74 1.8e-70 1 220 [] 55 283 .. 55 283 .. 0.96 Alignments for each domain: == domain 1 score: 237.7 bits; conditional E-value: 2.1e-74 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegseqklkvekvivhpnynsdtldnDiallkl 94 ivgg+e+ ++s pwq++l + ++fCGGsli+++wvlTAaHCv + +ss+kv+lg+h ++++e+++q+++v+k++ hp+y+s+t++nD+al+kl FUN_001884-T2 55 IVGGSETVKNSIPWQAMLRTDG-GQFCGGSLIHPQWVLTAAHCVMSesESSFKVWLGAHRREEKEDTTQEFSVAKIVRHPKYSSSTMENDMALIKL 149 89******************99.69*********************9************************************************* PP Trypsin 95 kspvtlgdavrpiclpaasssl...avgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsayggkvtdnmicagak.ggkdacqGDSGGPlv 185 ++p lg+ v +cl ++s +l + +cl+sGwG+ +++g +++tlqev vp+vs +ec + yg+++ ++m+cag+k ggkd+cqGDSGGPlv FUN_001884-T2 150 DRPSILGPGVGLVCLGDDSHHLpldDLNNQCLISGWGTLSSGGsQPNTLQEVMVPLVSPSECGRVYGQTMHSSMLCAGFKsGGKDSCQGDSGGPLV 245 *****************6666622456789**************************************************999************* PP Trypsin 186 csdg...eliGivswgkgcasgnkpgvytrvssyadwi 220 c+ +l G +s+gkgca+++ +gvy++v +++++i FUN_001884-T2 246 CQFSgkyFLEGATSFGKGCADPEAYGVYAKVRDLRQFI 283 **9999*************************9998876 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.0 8.6e-08 0.00074 2 104 .. 67 172 .. 66 185 .. 0.72 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 8.6e-08 DUF1986 2 PwladvyleGdlicsGvlidkswvlvsesclsdvdlehsyvsvvlGgaktkksvkgpye....qivrvdafk.dvpksevvllhlkskvsfsrhvl 92 Pw a + +G +c G li +wvl c+++ + s v lG+++ + + e +ivr + + ++ l+ l+++ v FUN_001884-T2 67 PWQAMLRTDGGQFCGGSLIHPQWVLTAAHCVMSESE--SSFKVWLGAHRREEKEDTTQEfsvaKIVRHPKYSsSTMENDMALIKLDRPSILGPGVG 160 9*****************************987665..7789999999887766555442122455554443145677788888888888888888 PP DUF1986 93 Ptfvpesrnene 104 + + + ++++ FUN_001884-T2 161 LVCLGDDSHHLP 172 777777777753 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.1 6.4e-07 0.0054 3 74 .. 82 166 .. 80 251 .. 0.57 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 6.4e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav....vaekvsvaladgreyaatvvaadp.......elDlallkv...sedgaglpplplgd 74 G ++ ++ vlT+aH+v ++ e+ a+++++ + +e+++ + ++p e D+al+k+ s g g++ + lgd FUN_001884-T2 82 GSLIHPQW-VLTAAHCVMSESESSFkvwlGAHRREEKEDTTQEFSVAKIVRHPkyssstmENDMALIKLdrpSILGPGVGLVCLGD 166 66788887.********888888886677555555555555555555444444688887777*******76655555555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (289 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 435 (0.0170288); expected 510.9 (0.02) Passed bias filter: 351 (0.0137405); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2814.23 // Query: FUN_001885-T1 [L=450] Description: FUN_001885 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-64 218.8 0.1 1.9e-64 218.0 0.1 1.4 1 Trypsin Trypsin 3.9e-31 108.5 0.2 6.2e-31 107.9 0.2 1.3 1 MAM MAM domain, meprin/A5/mu 0.00076 20.7 0.1 0.002 19.4 0.1 1.7 1 Trypsin_2 Trypsin-like peptidase domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 218.0 0.1 2.3e-68 1.9e-64 1 220 [] 192 444 .. 192 444 .. 0.96 Alignments for each domain: == domain 1 score: 218.0 bits; conditional E-value: 2.3e-68 Trypsin 1 ivggeeaqagsfpwqvslqlssg...............khfCGGslisenwvlTAaHCvsn...assvkvvlgehnisksegseqklkvekvivhp 78 ++gg +a++g++pwqv +++ ++ + +CGGsli ++w++TAaHCv++ +ss+ +++g+hn++ +eg+e++++++++i+hp FUN_001885-T1 192 VIGGVDANPGNWPWQVIFSRLNRelfvsslyivlllggGFTCGGSLIAPDWIVTAAHCVASsqpPSSYSIRVGDHNRQLNEGTEETVQGKEIIPHP 287 589****************99999**************99************************9******************************* PP Trypsin 79 nynsdt.ldnDiallklkspvtlgdavrpiclpaassslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsa.yggk.......vtdnm 164 ++++++ +nDial++l +pv+lg+++ ++clpa+++s++v +tc+++GwG t+ g + lq++++p vs+e c ++ ++ +td+m FUN_001885-T1 288 EFGKPSfANNDIALIRLVRPVKLGPRIGTVCLPAQGESVPVSATCYITGWGMTQYPGpAHNILQQAKLPPVSNEVCARKlA-QSpggghlkITDTM 382 ******67***********************************************************************62.334568899***** PP Trypsin 165 icagakgg.kdacqGDSGGPlvcsdg....eliGivswg.kgcasgnkpgvytrvssyadwi 220 icag +g+ ++ c GDSGGP+vc++ +l+G vswg +c+ +++v++rv++++dwi FUN_001885-T1 383 ICAGIEGKpQSGCFGDSGGPYVCQSSsgkwFLQGAVSWGsLSCDASDRYSVFARVAQFRDWI 444 ******555****************************************************9 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.9 0.2 7.2e-35 6.2e-31 1 158 [] 19 166 .. 19 166 .. 0.90 Alignments for each domain: == domain 1 score: 107.9 bits; conditional E-value: 7.2e-35 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvll 93 CdFe++ lCgwtq++sd++dW+r+++ s++tgp+s + ++G+y+++ets + +++a L+ ++s C++F+yhm+g++ +tl+++ FUN_001885-T1 19 CDFEKD-LCGWTQSKSDNFDWKRQQRRtpSSSTGPPSGQG--NTGYYVYIETSCPrRLNDSAILTFTGSNSSG--VCFSFYYHMYGNTTNTLNIYS 109 ******.*****************9888888888888776..99*********98677888888776555554..6******************97 PP MAM 94 reegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeCk 158 r +++ws sg+qg+ Wk+++ + + ++ + +e++rg+++ gdia+D is+s+g+C+ FUN_001885-T1 110 RG------QKVWSKSGNQGNVWKRDNFSIGA--GRYDLKIEGIRGQSYTGDIAVDSISVSSGPCS 166 63......479*******************9..99*****************************5 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.1 2.3e-07 0.002 3 89 .. 235 337 .. 232 411 .. 0.64 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 2.3e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav......vaekvsvaladgreyaatvvaadp.............elDlallkv.....sedgaglpplplgd 74 G ++++d ++T+aH+va+++ + + ++ l +g+e + v+ ++ + D+al+++ +++ g +lp FUN_001885-T1 235 GSLIAPDW-IVTAAHCVASSQPPSSysirvgD---HNRQLNEGTEET---VQGKEiiphpefgkpsfaNNDIALIRLvrpvkLGPRIGTVCLPAQG 323 78999998.********999999995553321...222222232222...22222344557899988777*******8776655555555666555 PP Trypsin_2 75 saplvggervyavGy 89 ++ + + ++y+ G FUN_001885-T1 324 ES-VPVSATCYITGW 337 44.444447777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (450 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 419 (0.0164024); expected 510.9 (0.02) Passed bias filter: 314 (0.012292); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4386.60 // Query: FUN_001886-T1 [L=161] Description: FUN_001886 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (161 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 466 (0.0182423); expected 510.9 (0.02) Passed bias filter: 367 (0.0143668); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1573.63 // Query: FUN_001887-T1 [L=460] Description: FUN_001887 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-67 228.1 0.5 1.6e-67 228.1 0.5 1.5 2 Trypsin Trypsin 7.7e-31 107.6 0.1 1.1e-30 107.1 0.1 1.2 1 MAM MAM domain, meprin/A5/mu 0.00059 21.1 0.1 0.0015 19.8 0.1 1.7 1 Trypsin_2 Trypsin-like peptidase domain 0.0043 17.9 0.0 0.011 16.6 0.0 1.7 2 DUF1986 Domain of unknown function (DUF1986) ------ inclusion threshold ------ 0.018 15.5 0.0 0.042 14.4 0.0 1.6 1 ParE_like ParE-like toxin domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 1.4 7.3e+03 155 155 .. 82 82 .. 38 117 .. 0.49 2 ! 228.1 0.5 3.1e-71 1.6e-67 1 220 [] 218 454 .. 218 454 .. 0.96 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 1.4 Trypsin 155 a 155 + FUN_001887-T1 82 Q 82 1 PP == domain 2 score: 228.1 bits; conditional E-value: 3.1e-71 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn...assvkvvlgehnisksegseqklkvekvivhpnynsdt.ldnDiall 92 ++gg +a++g++pwq++l +++ + +CGGsli ++w++TAaHCv++ +ss+ +++g+hn++ +eg+e+++++++vi+hp+yn+++ ++nDial+ FUN_001887-T1 218 VIGGVDAKPGNWPWQIALLRGG-RFICGGSLIAPDWIVTAAHCVASsqpPSSYSIRVGDHNRQLNEGTEETVQGKEVISHPEYNKPSiINNDIALI 312 589*****************99.89************************9*************************************77******* PP Trypsin 93 klkspvtlgdavrpiclpaassslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsa.yggk.......vtdnmicagakgg.kdacqG 178 +l +pv+lg++v ++clpa+++s++ +tc+++GwG+ k+ g + lq++++p vs+e c ++ ++ +t +micag +g+ + c+G FUN_001887-T1 313 RLVRPVKLGPRVGTVCLPAQGESVPISATCYITGWGKIKHPGsAHNILQQAKLPPVSNEVCARKlA-QSpggdrlkITGEMICAGVEGEpLSGCHG 407 ******************************************9*********************62.334568899**********95559***** PP Trypsin 179 DSGGPlvcsdg....eliGivswg.kgcasgnkpgvytrvssyadwi 220 DSGGP+vc++ +l+G vswg ca ++++v++rv+++++wi FUN_001887-T1 408 DSGGPYVCQSSsgnwFLQGAVSWGsPRCAASERYTVFARVAQFRNWI 454 **********99**********************************9 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.1 0.1 2.1e-34 1.1e-30 1 158 [] 45 192 .. 45 192 .. 0.90 Alignments for each domain: == domain 1 score: 107.1 bits; conditional E-value: 2.1e-34 MAM 1 CdFeegslCgwtqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvll 93 CdFe++ lCgwtq++sd++dW+r+++ s++tgpss + ++G+y+++ets+ + +++a L+ + + C++F+yhm+g++ +tl+++ FUN_001887-T1 45 CDFEND-LCGWTQSKSDNFDWKRQQSRtpSSSTGPSSGQG--NTGYYVYIETSRPrRLNDNAILTFTGSNGR--DVCFSFYYHMYGNTINTLNIYS 135 ******.*****************9888777788877666..99*********9978888888887665555..46******************97 PP MAM 94 reegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeCk 158 r +++ws s +qg+ W++a+ + + ++ + +e++rg+++ gdia+D is+s+g+C+ FUN_001887-T1 136 RG------QKVWSKSDNQGNVWRKASFSIRA--GRYDLKIEGIRGQSYTGDIAVDSISVSNGPCS 192 63......479******************99..99*****************************5 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.1 2.9e-07 0.0015 3 89 .. 245 347 .. 243 420 .. 0.61 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 2.9e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav..........vaekvsvaladgreyaatvvaadp........elDlallkv.....sedgaglpplplgds 75 G ++++d ++T+aH+va+++ + + + +++++++ v +p + D+al+++ +++ g +lp FUN_001887-T1 245 GSLIAPDW-IVTAAHCVASSQPPSSysirvgdhnrQ-----LNEGTEETVQGKEVISHPeynkpsiiNNDIALIRLvrpvkLGPRVGTVCLPAQG- 333 78999998.********9999999855544322111.....1222222222223333335677687777*******7776555555555555544. PP Trypsin_2 76 aplvggervyavGy 89 +++ ++y+ G FUN_001887-T1 334 ESVPISATCYITGW 347 34444457777765 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 2.1e-06 0.011 1 98 [. 229 331 .. 229 346 .. 0.67 2 ? -3.1 0.0 2.7 1.4e+04 9 18 .. 388 397 .. 385 397 .. 0.85 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 2.1e-06 DUF1986 1 wPwladvyleGdlicsGvlidkswvlvsesclsdvdlehsyvsvvlGgaktkksvkgpyeqiv..rv....dafk.dvpksevvllhlkskvsfsr 89 wPw + G +ic G li +w++ c+ + + sy s+ +G + +++ +g e ++ v + k + + ++ l+ l ++v+ FUN_001887-T1 229 WPWQIALLRGGRFICGGSLIAPDWIVTAAHCVASSQPPSSY-SIRVGDHNRQLN-EGTEETVQgkEVishpEYNKpSIINNDIALIRLVRPVKLGP 322 9*******************************999997777.777777765443.34433333102200002222246677777777777777777 PP DUF1986 90 hvlPtfvpe 98 v + +p FUN_001887-T1 323 RVGTVCLPA 331 776666665 PP == domain 2 score: -3.1 bits; conditional E-value: 2.7 DUF1986 9 leGdlicsGv 18 + G++ic+Gv FUN_001887-T1 388 ITGEMICAGV 397 789*****98 PP >> ParE_like ParE-like toxin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 8.1e-06 0.042 35 67 .] 269 301 .. 263 301 .. 0.95 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 8.1e-06 ParE_like 35 lsipvgrryRLLsrdegktlepwellsHedYnk 67 +si+vg + R L + +++t++ e++sH +Ynk FUN_001887-T1 269 YSIRVGDHNRQLNEGTEETVQGKEVISHPEYNK 301 8*******************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (460 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 514 (0.0201214); expected 510.9 (0.02) Passed bias filter: 391 (0.0153063); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4528.76 // Query: FUN_001888-T1 [L=437] Description: FUN_001888 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-67 228.3 0.3 1.8e-67 227.9 0.3 1.1 1 Trypsin Trypsin 6.7e-20 72.0 0.1 1.1e-19 71.3 0.1 1.3 1 F5_F8_type_C F5/8 type C domain 0.00035 21.6 0.0 0.0016 19.5 0.0 2.0 2 F5_F8_type_C_2 NedA-like, galactose-binding domain 0.00061 21.0 0.1 0.0015 19.8 0.1 1.7 1 Trypsin_2 Trypsin-like peptidase domain ------ inclusion threshold ------ 0.014 16.3 0.0 0.024 15.5 0.0 1.4 1 DUF1986 Domain of unknown function (DUF1986) 0.055 14.0 0.0 0.11 13.1 0.0 1.4 1 ParE_like ParE-like toxin domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 227.9 0.3 4.2e-71 1.8e-67 1 220 [] 195 431 .. 195 431 .. 0.96 Alignments for each domain: == domain 1 score: 227.9 bits; conditional E-value: 4.2e-71 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn...assvkvvlgehnisksegseqklkvekvivhpnynsdt.ldnDiall 92 ++gg +a++g++pwq++l +++ + +CGGsli ++w++TAaHCv++ + s+ +++g+hn++ +eg+e++++++++i+hp+yn+++ ++nDial+ FUN_001888-T1 195 VIGGVDARPGNWPWQIALLRGG-RFICGGSLIAPDWIVTAAHCVASsqpPCSYSIRVGDHNRQLNEGTEETVQGKEIISHPEYNKPSlINNDIALI 289 589*****************99.89*********************999899999********************************77******* PP Trypsin 93 klkspvtlgdavrpiclpaassslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsa.yggk.......vtdnmicagakgg.kdacqG 178 +l +pv+lg++v ++clpa+++s++v +tc+++GwG+ k g + lq++++p vs+e c ++ ++ +td+micag +g+ + c+G FUN_001888-T1 290 RLVRPVKLGPRVGTVCLPAQGESVPVSATCYITGWGKIKYPGsAHNILQQAKLPPVSNEVCARKlA-QSpggdrlnITDKMICAGIEGEpLSGCHG 384 *************************************9999999********************62.334568899***********5559***** PP Trypsin 179 DSGGPlvcsdg....eliGivswg.kgcasgnkpgvytrvssyadwi 220 DSGGP+vc++ +l+G vswg ca ++++v++rv+++++wi FUN_001888-T1 385 DSGGPYVCQSSsgnwFLQGAVSWGsPRCAASERYSVFARVAQFRNWI 431 **********99**********************************9 PP >> F5_F8_type_C F5/8 type C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.3 0.1 2.5e-23 1.1e-19 1 126 [. 37 166 .. 37 167 .. 0.86 Alignments for each domain: == domain 1 score: 71.3 bits; conditional E-value: 2.5e-23 F5_F8_type_C 1 qitasssesgeg.paaaaldGnkntaWssssnddk.qwlqvdLgkekkitgvvlqgrqdggngrvksykieysddgenWtevkd...ekv..kgns 89 q+tass++s+ + p +l++ ++++W++ +++++ wlqvd+g+ + +v +qg + n++v ++++++s+dg +W + d +k+ + FUN_001888-T1 37 QMTASSYYSSLYyPYFGRLHNIRGGGWAGRTPSNPsDWLQVDFGRIALVCAVATQGNPYL-NEWVIDFSLSFSSDGASWMHSNDsqgNKMvfTRLG 131 789****888888*******99999***55555555********************9877.******************98888888555564444 PP F5_F8_type_C 90 dnstpvtntfdkpvkaryvrlvptswnggngialraE 126 +ns + ++t++ p++ary+r++p s++++ +lr+E FUN_001888-T1 132 NNSYVDQQTLPAPMSARYIRFHPISQHSW--NTLRVE 166 4669*********************7777..777777 PP >> F5_F8_type_C_2 NedA-like, galactose-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 3.8e-07 0.0016 13 90 .] 67 152 .. 60 152 .. 0.83 2 ? -1.6 0.0 1.4 6e+03 45 60 .. 241 261 .. 231 276 .. 0.67 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 3.8e-07 F5_F8_type_C_2 13 tanedpqwlqvDLgssytissvvltnegdccgerlkgykiqvsddg.........snwttvatvt.ngpggntetitf.navtaryvrv 90 t ++ ++wlqvD+g + +v + + +e + +++++ s+dg + +++v t+ n++ +++ t+ ++++ary+r+ FUN_001888-T1 67 TPSNPSDWLQVDFGRIALVCAVATQGNP-YLNEWVIDFSLSFSSDGaswmhsndsQGNKMVFTRLgNNS--YVDQQTLpAPMSARYIRF 152 337899*******************999.79***************88888888777777777753555..666667777*******96 PP == domain 2 score: -1.6 bits; conditional E-value: 1.4 F5_F8_type_C_2 45 erlkgykiqvsddg.....sn 60 + + +y+i+v+d + ++ FUN_001888-T1 241 QPPCSYSIRVGDHNrqlneGT 261 566789999999984443333 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.1 3.4e-07 0.0015 3 89 .. 222 324 .. 220 397 .. 0.62 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 3.4e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav......vaekvsvaladgreyaat..vvaadp.............elDlallkv.....sedgaglpplpl 72 G ++++d ++T+aH+va+++ + + ++++ ++t v+ ++ + D+al+++ +++ g +lp FUN_001888-T1 222 GSLIAPDW-IVTAAHCVASSQPPCSysirvgD--------HNRQLNEGTeeTVQGKEiishpeynkpsliNNDIALIRLvrpvkLGPRVGTVCLPA 308 78999998.********999999995554331........22222222222222222333445666677666*******88776666666666665 PP Trypsin_2 73 gdsaplvggervyavGy 89 ++ + + ++y+ G FUN_001888-T1 309 QGES-VPVSATCYITGW 324 5544.444447888775 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.0 5.6e-06 0.024 1 53 [. 206 257 .. 206 323 .. 0.64 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 5.6e-06 DUF1986 1 wPwladvyleGdlicsGvlidkswvlvsesclsdvdlehsyvsvvlGgaktkk 53 wPw + G +ic G li +w++ c+ + + sy s+ +G + ++ FUN_001888-T1 206 WPWQIALLRGGRFICGGSLIAPDWIVTAAHCVASSQPPCSY-SIRVGDHNRQL 257 9*******************************999887777.56666665433 PP >> ParE_like ParE-like toxin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 2.5e-05 0.11 35 67 .] 246 278 .. 244 278 .. 0.97 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2.5e-05 ParE_like 35 lsipvgrryRLLsrdegktlepwellsHedYnk 67 +si+vg + R L + +++t++ e++sH +Ynk FUN_001888-T1 246 YSIRVGDHNRQLNEGTEETVQGKEIISHPEYNK 278 89******************************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (437 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 348 (0.013623); expected 510.9 (0.02) Passed bias filter: 307 (0.012018); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 4366.76 // Query: FUN_001889-T1 [L=1492] Description: FUN_001889 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-06 26.2 0.2 8.6e-06 26.2 0.2 4.4 4 FAM186A-B_C FAM186A/B, C-terminal Domain annotation for each model (and alignments): >> FAM186A-B_C FAM186A/B, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -6.0 8.8 1 2.6e+04 63 167 .. 173 272 .. 167 312 .. 0.64 2 ? -3.1 4.1 0.3 7.7e+03 96 139 .. 638 681 .. 610 736 .. 0.69 3 ? -4.3 0.3 0.73 1.9e+04 70 102 .. 1033 1065 .. 1023 1071 .. 0.67 4 ! 26.2 0.2 3.4e-10 8.6e-06 12 149 .. 1095 1223 .. 1088 1251 .. 0.84 Alignments for each domain: == domain 1 score: -6.0 bits; conditional E-value: 1 FAM186A-B_C 63 fqslRqevinhiqairetgkgykaqnlyvflenidrlqkkvlqawtdkqkdleekrreclssmvtlFpkLklewnlhLstpvvlstkkkkikssek 158 + ++ ++vi+ ++++ +++ ++l++ l+ + + + + t+k +++++ +e+ +m +++ ++ +++++ v++ + kk++ k FUN_001889-T1 173 LATVSKDVIKALEVANPKETKKGKKKLEKALQ----QSQHDIMSLTEKLLRVQNDLEESEGKMSQMYKSMEI-KQVEIERLKVQADSAKKATDIVK 263 55666778888887776666666666665554....555556667777777777777777899999988875.34666666666666555554444 PP FAM186A-B_C 159 llkrptlek 167 lk ++ k FUN_001889-T1 264 DLKADVTAK 272 444433333 PP == domain 2 score: -3.1 bits; conditional E-value: 0.3 FAM186A-B_C 96 idrlqkkvlqawtdkqkdleekrreclssmvtlFpkLklewnlh 139 + +l++k + + +k+ ee +++ l++ ++ +kL++ nl+ FUN_001889-T1 638 LAELKNKYIVKTNSLKKQNEESQNSFLREKEAMLSKLREAENLK 681 45677777777777788889999999999999999999988775 PP == domain 3 score: -4.3 bits; conditional E-value: 0.73 FAM186A-B_C 70 vinhiqairetgkgykaqnlyvflenidrlqkk 102 + +h++a + ++ + qn+ v+ + d++ ++ FUN_001889-T1 1033 LQQHMDAETKFHQEQTSQNVAVMTDMQDTITQL 1065 556777777777777777777777766665554 PP == domain 4 score: 26.2 bits; conditional E-value: 3.4e-10 FAM186A-B_C 12 rknLqlLseaakelglpaelrskalelitttleldvlrLqlLcrkYilyrlfqslRqevinhiqairetgkgykaqnlyvflenidrlqkkvlq 105 +n ++L++a++e +l+ + s e + + + l ++rL ++r+Y ++r ++++ +++ +h ++ + + l+++++lq+k+ + FUN_001889-T1 1095 ERNSKILKRAVNERRLSDDSFSVIMEHMDHYVSLPAQRLAHIVRRYSHHRSMKEIERSL-KHGGVLD--------EGVFSTLDKMESLQNKRAE 1179 47899*******************************************99998776553.3333333........2356689************ PP FAM186A-B_C 106 awtdkqkdleekrreclssmvtlFpkLklewnlhLstpvvlstk 149 +w dk ++ +r++ ++++t F +L++e+ + L +pv FUN_001889-T1 1180 RWGDKMDKYASERERLAEQLTTCFENLEQETGIFLIKPVYSFKG 1223 **************************************976543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1492 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3244 (0.126992); expected 510.9 (0.02) Passed bias filter: 609 (0.0238403); expected 510.9 (0.02) Passed Vit filter: 125 (0.00489333); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.79u 0.40s 00:00:01.19 Elapsed: 00:00:00.44 # Mc/sec: 13749.85 // Query: FUN_001889-T2 [L=1282] Description: FUN_001889 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.7e-06 26.4 0.3 7.7e-06 26.4 0.3 3.8 3 FAM186A-B_C FAM186A/B, C-terminal Domain annotation for each model (and alignments): >> FAM186A-B_C FAM186A/B, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 4.1 0.25 6.5e+03 96 139 .. 428 471 .. 400 526 .. 0.69 2 ? -4.0 0.3 0.57 1.5e+04 70 102 .. 823 855 .. 813 863 .. 0.67 3 ! 26.4 0.3 3e-10 7.7e-06 12 149 .. 885 1013 .. 878 1037 .. 0.84 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 0.25 FAM186A-B_C 96 idrlqkkvlqawtdkqkdleekrreclssmvtlFpkLklewnlh 139 + +l++k + + +k+ ee +++ l++ ++ +kL++ nl+ FUN_001889-T2 428 LAELKNKYIVKTNSLKKQNEESQNSFLREKEAMLSKLREAENLK 471 45677777777777788889999999999999999999988775 PP == domain 2 score: -4.0 bits; conditional E-value: 0.57 FAM186A-B_C 70 vinhiqairetgkgykaqnlyvflenidrlqkk 102 + +h++a + ++ + qn+ v+ + d++ ++ FUN_001889-T2 823 LQQHMDAETKFHQEQTSQNVAVMTDMQDTITQL 855 556777777777777777777777766665554 PP == domain 3 score: 26.4 bits; conditional E-value: 3e-10 FAM186A-B_C 12 rknLqlLseaakelglpaelrskalelitttleldvlrLqlLcrkYilyrlfqslRqevinhiqairetgkgykaqnlyvflenidrlqkkvlq 105 +n ++L++a++e +l+ + s e + + + l ++rL ++r+Y ++r ++++ +++ +h ++ + + l+++++lq+k+ + FUN_001889-T2 885 ERNSKILKRAVNERRLSDDSFSVIMEHMDHYVSLPAQRLAHIVRRYSHHRSMKEIERSL-KHGGVLD--------EGVFSTLDKMESLQNKRAE 969 47899*******************************************99998776553.3333333........2356689************ PP FAM186A-B_C 106 awtdkqkdleekrreclssmvtlFpkLklewnlhLstpvvlstk 149 +w dk ++ +r++ ++++t F +L++e+ + L +pv FUN_001889-T2 970 RWGDKMDKYASERERLAEQLTTCFENLEQETGIFLIKPVYSFKG 1013 **************************************966543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1282 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3302 (0.129262); expected 510.9 (0.02) Passed bias filter: 669 (0.0261891); expected 510.9 (0.02) Passed Vit filter: 110 (0.00430613); expected 25.5 (0.001) Passed Fwd filter: 34 (0.00133098); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.67u 0.41s 00:00:01.08 Elapsed: 00:00:00.44 # Mc/sec: 11819.27 // Query: FUN_001890-T1 [L=135] Description: FUN_001890 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (135 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 344 (0.0134664); expected 510.9 (0.02) Passed bias filter: 291 (0.0113917); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1357.24 // Query: FUN_001891-T1 [L=75] Description: FUN_001891 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (75 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 587 (0.0229791); expected 510.9 (0.02) Passed bias filter: 432 (0.0169113); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 771.61 // Query: FUN_001892-T1 [L=217] Description: FUN_001892 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.7e-07 29.4 0.7 1.3 9.8 0.1 3.4 3 DUF7196 Domain of unknown function (DUF7196) 0.009 16.6 6.9 4.7 7.9 0.5 4.1 4 Plasmod_Pvs28 Pvs28 EGF domain ------ inclusion threshold ------ 0.041 14.1 0.3 84 3.5 0.0 3.4 4 SH3_2 Variant SH3 domain Domain annotation for each model (and alignments): >> DUF7196 Domain of unknown function (DUF7196) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.00039 3.3 3 46 .. 39 79 .. 38 85 .. 0.82 2 ! 7.6 0.0 0.00077 6.5 3 45 .. 94 134 .. 93 137 .. 0.81 3 ! 9.8 0.1 0.00016 1.3 3 47 .. 150 192 .. 149 196 .. 0.89 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00039 DUF7196 3 CnCGggaraaaaggdtlgYyvilPDgtvlpeadeapyftilEAr 46 C+C ra+++g++ ++v +P++ ++p + +++ ++A+ FUN_001892-T1 39 CRCQT--RASSQGNQFRLSQVSMPNKGLVPR-ESVQVIPSVDAK 79 66766..899********************6.666666666665 PP == domain 2 score: 7.6 bits; conditional E-value: 0.00077 DUF7196 3 CnCGggaraaaaggdtlgYyvilPDgtvlpeadeapyftilEA 45 C+C ++++ +g+ + ++v +P++ ++p+ + +++ + A FUN_001892-T1 94 CRCQT-RASSLQGNRFSPSQVLMPNKGLVPS-ESVQVIPSVNA 134 99999.799999******************7.55555555555 PP == domain 3 score: 9.8 bits; conditional E-value: 0.00016 DUF7196 3 CnCGggaraaaaggdtlgYyvilPDgtvlpeadeapyftilEAra 47 C+C ++++ +g+ + ++v +P++ ++p+ + ++++ ++A++ FUN_001892-T1 150 CRCKT-RASSLQGNRCSPSQVSMPNKGLVPS-ESVQVISSVDAKQ 192 99999.799999******************6.8889999999875 PP >> Plasmod_Pvs28 Pvs28 EGF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.021 1.7e+02 21 30 .. 34 43 .. 32 67 .. 0.87 2 ? 3.5 0.0 0.013 1.1e+02 21 32 .. 89 100 .. 87 125 .. 0.82 3 ! 7.9 0.5 0.00055 4.7 21 40 .. 145 164 .. 135 165 .. 0.88 4 ? 3.2 0.1 0.015 1.3e+02 21 32 .. 201 212 .. 199 217 .] 0.80 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.021 Plasmod_Pvs28 21 snhykCsCni 30 s+++kC C + FUN_001892-T1 34 SGYPKCRCQT 43 789*****86 PP == domain 2 score: 3.5 bits; conditional E-value: 0.013 Plasmod_Pvs28 21 snhykCsCniGy 32 s+++kC C + + FUN_001892-T1 89 SGYPKCRCQTRA 100 789*****8755 PP == domain 3 score: 7.9 bits; conditional E-value: 0.00055 Plasmod_Pvs28 21 snhykCsCniGyvllnenkC 40 s+++kC C++ + l++n C FUN_001892-T1 145 SGYPKCRCKTRASSLQGNRC 164 79********9999999999 PP == domain 4 score: 3.2 bits; conditional E-value: 0.015 Plasmod_Pvs28 21 snhykCsCniGy 32 s+++kC C + + FUN_001892-T1 201 SGYLKCRCQTKA 212 789*****9865 PP >> SH3_2 Variant SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.0 1.6 1.4e+04 44 53 .. 7 16 .. 6 16 .. 0.83 2 ? 3.5 0.0 0.0098 84 44 55 .] 62 73 .. 47 73 .. 0.86 3 ? 3.3 0.0 0.011 93 44 55 .] 118 129 .. 104 129 .. 0.90 4 ? 3.3 0.0 0.011 96 44 55 .] 174 185 .. 164 185 .. 0.90 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 1.6 SH3_2 44 kGlvPstave 53 kGl P+++v+ FUN_001892-T1 7 KGLTPREWVQ 16 7999999995 PP == domain 2 score: 3.5 bits; conditional E-value: 0.0098 SH3_2 44 kGlvPstaveei 55 kGlvP+++v++i FUN_001892-T1 62 KGLVPRESVQVI 73 8********985 PP == domain 3 score: 3.3 bits; conditional E-value: 0.011 SH3_2 44 kGlvPstaveei 55 kGlvPs++v++i FUN_001892-T1 118 KGLVPSESVQVI 129 8********985 PP == domain 4 score: 3.3 bits; conditional E-value: 0.011 SH3_2 44 kGlvPstaveei 55 kGlvPs++v++i FUN_001892-T1 174 KGLVPSESVQVI 185 8********985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (217 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 296 (0.0115874); expected 510.9 (0.02) Passed bias filter: 143 (0.00559796); expected 510.9 (0.02) Passed Vit filter: 12 (0.000469759); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2184.47 // Query: FUN_001893-T1 [L=341] Description: FUN_001893 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.15 12.7 0.4 0.8 10.4 0.1 2.1 2 Antiterm Antitermination protein Q Domain annotation for each model (and alignments): >> Antiterm Antitermination protein Q # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.069 1.8e+03 65 81 .. 31 47 .. 19 55 .. 0.81 2 ? 10.4 0.1 3.1e-05 0.8 4 77 .. 128 201 .. 126 205 .. 0.78 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.069 Antiterm 65 ektkkkvldvLvskafk 81 ++ k++++d Lv+ ++ FUN_001893-T1 31 KNHKNPFMDDLVKSSYQ 47 678999******87775 PP == domain 2 score: 10.4 bits; conditional E-value: 3.1e-05 Antiterm 4 sdalr..ctdvgaaldekqskarGvavfkeCercgkrgysrldeteaieallkla.pdltektwektkkkvldvLvs 77 sd+lr ++d+g a+ + + G +v+ ++c k+ y + + ++ +++ +la ++l ++ k +k v+++L++ FUN_001893-T1 128 SDKLRvlVNDIGIAMKKLGYALYGGKVY---KKCDKAKYTYSYKCKVEAYVNDLAaNELLKARLLKDMKRVIEILAN 201 677777789*******************...6667777777788888888888761456666688888999999886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (341 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 585 (0.0229008); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3404.81 // Query: FUN_001894-T1 [L=165] Description: FUN_001894 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (165 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 689 (0.026972); expected 510.9 (0.02) Passed bias filter: 574 (0.0224702); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1621.56 // Query: FUN_001896-T1 [L=117] Description: FUN_001896 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (117 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1065 (0.0416911); expected 510.9 (0.02) Passed bias filter: 560 (0.0219221); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1185.11 // Query: FUN_001897-T1 [L=210] Description: FUN_001897 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (210 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1246 (0.0487767); expected 510.9 (0.02) Passed bias filter: 776 (0.0303778); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2075.99 // Query: FUN_001898-T1 [L=304] Description: FUN_001898 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-61 206.5 12.5 7.7e-43 147.3 3.1 2.0 2 Beta-prop_WDR5 WDR5 beta-propeller domain 2.7e-56 191.2 9.4 1.5e-24 87.1 0.4 2.6 3 WD40_Prp19 Prp19 WD40 domain 1.5e-53 182.1 11.7 4.9e-19 68.9 2.4 3.2 3 Beta-prop_THOC3 THOC3 beta-propeller domain 3.3e-53 176.3 26.5 3.8e-11 43.5 0.0 7.2 7 WD40 WD domain, G-beta repeat 1.2e-52 178.7 7.7 1.8e-39 135.8 0.6 2.4 2 Beta-prop_WDR3_1st WDR3 first beta-propeller domain 3.4e-41 141.9 12.0 6.3e-33 114.7 3.1 3.7 3 Beta-prop_WDR3_2nd WDR3 second beta-propeller domain 8.4e-40 137.2 5.5 7e-17 62.0 0.2 4.2 4 WD40_WDHD1_1st WDHD1 first WD40 domain 3.2e-35 122.2 7.2 6.2e-12 45.6 2.5 3.3 4 WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain 4.1e-35 122.0 7.0 4.6e-25 89.0 0.3 3.5 3 WD40_CDC20-Fz CDC20/Fizzy WD40 domain 8.3e-35 120.9 1.6 2.4e-19 70.2 0.1 3.5 3 Beta-prop_EML_2 Echinoderm microtubule-associated 1e-30 107.3 1.7 4.6e-20 72.3 0.3 3.3 3 WDR55 WDR55 5.4e-30 105.0 7.6 2.7e-26 92.9 2.6 2.1 2 WD40_Gbeta G protein beta WD-40 repeat protei 1.2e-27 97.4 10.8 5.2e-20 72.3 0.0 3.5 3 EIF3I EIF3I 4.2e-26 92.5 7.7 8.3e-11 42.2 0.0 4.3 3 Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller 3.5e-25 89.3 7.4 5.8e-14 52.3 0.1 4.0 4 Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain 6.3e-24 85.2 0.8 3.4e-09 36.8 0.0 3.4 3 Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller 1.2e-22 80.4 0.8 0.00014 22.5 0.0 5.5 5 ANAPC4_WD40 Anaphase-promoting complex subunit 1.5e-22 80.5 8.0 4.9e-15 55.9 2.0 3.0 2 Beta-prop_TEP1_2nd TEP-1 second beta-propeller 1.9e-20 73.9 0.7 1.1e-15 58.3 0.0 2.5 2 Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller 6.3e-17 61.8 7.2 0.00023 21.6 0.0 5.6 5 Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller 3e-14 53.5 5.8 5.8e-07 29.6 0.3 4.8 5 Beta-prop_WDR75_1st WD repeat-containing protein 75 fi 3.4e-14 53.4 0.6 9.4e-08 32.2 0.0 3.3 3 WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain 3.6e-14 53.4 0.3 2.1e-12 47.5 0.1 2.1 2 Beta-prop_ACSF4 Beta-alanine-activating enzyme, be 3.6e-13 49.6 7.0 5.5e-09 35.9 1.0 3.4 2 Beta-prop_IFT122_1st IFT122 first beta-propeller 9.6e-13 48.7 5.9 5.1e-09 36.5 0.8 3.8 2 Beta-prop_EML Echinoderm microtubule-associated 3e-11 43.5 1.3 5.1e-07 29.6 0.3 2.8 2 Beta-prop_Aladin Aladin seven-bladed propeller 2.9e-10 40.2 3.0 0.00011 21.9 0.0 3.5 3 WDR90_beta-prop_4th WDR90, 4th beta-propeller 3.2e-10 40.4 6.0 0.13 12.1 0.0 5.7 6 Beta-prop_RIG_2nd RIG second beta-propeller 2.5e-09 37.1 0.3 2.4e-07 30.6 0.0 3.0 2 Beta-prop_WDR19_1st WDR19 first beta-propeller 4.6e-09 36.3 2.2 0.011 15.4 0.0 4.0 4 Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal 7.3e-09 35.3 0.0 0.0001 21.6 0.0 2.5 3 Tricorn_2nd Tricorn protease second beta prope 8.2e-09 35.2 4.1 0.0015 17.8 0.0 3.5 4 Beta-prop_WDR41 WDR41 1.4e-08 34.6 2.2 3.6e-05 23.4 0.3 3.5 3 Beta-prop_VPS8 Vps8 beta-propeller 1.4e-08 34.3 1.1 0.027 13.6 0.0 3.5 3 Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-prope 1.7e-08 34.2 0.3 0.011 15.1 0.0 3.1 3 Beta-prop_SPT8 SPT8 beta propeller 2.2e-08 34.1 0.3 2.5e-05 24.1 0.0 3.1 3 Beta-prop_NWD2_C NWD2 C-terminal beta-propeller 2.6e-08 34.0 5.1 0.00015 21.7 0.1 3.5 4 Beta-prop_Vps41 Vps42 beta-propeller 3.1e-07 30.5 11.1 0.012 15.4 0.0 4.5 5 WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 3.7e-07 30.4 3.6 5.8e-06 26.4 0.1 3.1 3 Beta-prop_EIPR1 EIPR1 beta-propeller 4.3e-07 29.9 0.0 0.12 12.0 0.0 2.9 3 PROPPIN PROPPIN 4.4e-07 29.3 0.5 0.00032 19.8 0.0 3.2 3 Cytochrom_D1 Cytochrome D1 heme domain 8.7e-07 28.6 10.0 0.00079 18.9 0.0 4.5 6 NBCH_WD40 Neurobeachin beta propeller domain 1.2e-06 29.0 0.1 1.2 9.7 0.0 4.0 4 RMC1_N Regulator of MON1-CCZ1 complex, N- 1.4e-06 28.3 0.0 0.00069 19.4 0.0 3.0 5 Beta-prop_HPS5 HPS5 beta-propeller 1.5e-06 27.9 0.2 0.23 10.8 0.0 3.1 3 Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 1.5e-06 27.8 10.0 0.0088 15.4 0.2 3.0 3 Beta-prop_SCAP SCAP Beta-propeller 5.4e-05 22.5 3.4 1.4 8.1 0.0 3.9 5 Beta-prop_IFT140_1st IFT140 first beta-propeller 8.7e-05 22.4 0.0 0.0017 18.2 0.0 2.1 2 Beta-prop_NUP159_NUP214 NUP159/214 beta propeller 0.00011 21.8 10.7 0.0029 17.1 0.1 3.1 3 Beta-prop_DCAF12 DDB1- and CUL4-associated factor 1 0.00043 19.5 3.8 0.16 11.0 0.0 3.5 4 Beta-prop_RIG_1st RIG first beta-propeller 0.00043 20.2 0.1 0.076 12.9 0.0 3.0 4 WD40_like WD40-like domain 0.0005 19.6 1.7 2.9 7.3 0.1 4.3 3 Ge1_WD40 WD40 region of Ge1, enhancer of mR 0.00052 19.7 0.3 0.01 15.5 0.1 2.3 2 WDR54 WDR54 0.0041 16.8 0.7 1.5 8.3 0.0 3.2 3 PEP5_VPS11_N PEP5/VPS11 N-terminal 0.0065 16.0 0.1 0.83 9.0 0.0 2.6 2 WD_LRWD1 Leucine-rich repeat and WD repeat- 0.0089 15.4 0.1 0.24 10.7 0.1 2.5 3 PALB2_WD40 Partner and localizer of BRCA2 WD4 ------ inclusion threshold ------ 0.013 15.0 0.7 8.1 5.8 0.1 3.4 2 Beta-prop_LRRK2 LRRK2 beta propeller 0.015 15.1 0.1 15 5.2 0.0 3.1 3 KNTC1_N KNTC1, N-terminal 0.026 14.1 2.7 31 4.0 0.0 4.3 4 Beta-prop_IFT140_2nd IFT140 second beta-propeller 0.028 14.9 0.5 21 5.6 0.1 3.5 3 DUF7037 Domain of unknown function (DUF703 0.031 13.6 0.0 0.15 11.3 0.0 2.0 1 Vgb_lyase Virginiamycin B lyase family 0.059 12.6 0.8 3.8 6.6 0.0 3.3 3 Nucleoporin_N Nup133 N terminal like 0.072 13.6 0.1 34 5.1 0.0 3.5 3 PD40 WD40-like Beta Propeller Repeat 0.08 12.8 0.0 2.1 8.2 0.0 2.3 2 Beta-prop_IFT122_2nd IFT122 second beta-propeller 0.16 12.7 0.0 0.3 11.8 0.0 1.4 1 Chorion_S16 Chorion protein S16 0.21 11.0 2.1 0.49 9.8 0.3 2.2 2 Beta-prop_pof12 F-box protein pof12 beta-propeller Domain annotation for each model (and alignments): >> Beta-prop_WDR5 WDR5 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.1 1.9 2.3e-20 8.7e-18 45 166 .. 12 139 .. 2 150 .. 0.64 2 ! 147.3 3.1 2e-45 7.7e-43 9 160 .. 150 301 .. 142 303 .. 0.97 Alignments for each domain: == domain 1 score: 65.1 bits; conditional E-value: 2.3e-20 Beta-prop_WDR5 45 eghkkGisdvawssd....skllasaSDDktvriwdvetgk..llktlkgHtnyvfcvaFnpkgnllvSGsfDetvrlWdvrtgkclktlpaHsd 133 ++h++ i +vaw + ++ +++++ D +v+ w+ ++ k l +++gH+ v++v+ n +g+l +S+s D +r+Wd+++gk lk + + FUN_001898-T1 12 QAHEDSIWTVAWGTSdkdgTENIVTGAVDDMVKCWRWTEDKlhLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPV 106 56777777777754323344567777777777777776665323345677777777777777777777777777777777777777777777666 PP Beta-prop_WDR5 134 pvsavdfnrdgtlivsssyDgliriwdtetgqc 166 +v+f+ d+++i+++s+ g i++ +e+g+ FUN_001898-T1 107 DTWTVAFSPDSRFIATGSHAGKINLIGVESGKK 139 667777777777777777777777766666654 PP == domain 2 score: 147.3 bits; conditional E-value: 2e-45 Beta-prop_WDR5 9 vssvkfspdgkllasasaDktikiwdveegklektleghkkGisdvawssdskllasaSDDktvriwdvetgkllktlkgHtnyvfcvaFnpkgn 103 s+ +spdg+++a+ + D++i+i+d+++gkl +tlegh++ i ++++s+ds+ll++aSDD+ ++i+dv++++l tl+gH ++v+ v+F p+++ FUN_001898-T1 150 TMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNT 244 57899****************************************************************************************** PP Beta-prop_WDR5 104 llvSGsfDetvrlWdvrtgkclktlpaHsdpvsavdfnrdgtlivsssyDgliriwd 160 vS+s D+tv++Wd+ + +c++t+ +Hsd+v +v++n +g+ ivs s D + +++ FUN_001898-T1 245 HFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 ****************************************************99987 PP >> WD40_Prp19 Prp19 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.1 0.4 3.8e-27 1.5e-24 46 228 .. 12 197 .. 3 199 .. 0.89 2 ! 51.7 0.0 2.2e-16 8.6e-14 138 207 .. 150 219 .. 140 222 .. 0.92 3 ! 70.4 1.8 4.4e-22 1.7e-19 9 118 .. 192 300 .. 191 303 .. 0.96 Alignments for each domain: == domain 1 score: 87.1 bits; conditional E-value: 3.8e-27 WD40_Prp19 46 kghtkkvtavafhpse....dvlvsasaDktvrvwkkeek..etaatlkkhkaevtslsvhptgdylvsaskDgtwalhdletgktllkvkdeesk 135 ++h+ + +va+ +s+ +++v+++ D v+ w+ +e+ + ++ h+ v+s++v+ tg++++s+s D+ + ++dle+gk+l+ + FUN_001898-T1 12 QAHEDSIWTVAWGTSDkdgtENIVTGAVDDMVKCWRWTEDklHLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPV- 106 78999999****8765223369*************99887335667899**************************************99987664. PP WD40_Prp19 136 eaitsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsasedgtvklWDLRklknfktleldeeskvnsvaF 228 + +++f PD +++tG++ g++++ ++s+k+ l+ + s+a+S +G y+A ++ dg ++++DL k ++tle ++ + ++s++F FUN_001898-T1 107 -DTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHA-MPIRSLTF 197 .6889**********************************9999999**********************************9865.67888877 PP == domain 2 score: 51.7 bits; conditional E-value: 2.2e-16 WD40_Prp19 138 itsaqfHPDGlllgtGtkdgtvkiWDiksqknvasleghsgavtslaFSeNGYyLAsasedgtvklWDLR 207 s+++ PDG+ +++G dg+++i+D+ ++k + +legh+ +++sl+FS + L +as+d+++k++D FUN_001898-T1 150 TMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQ 219 568999**************************************************************75 PP == domain 3 score: 70.4 bits; conditional E-value: 4.4e-22 WD40_Prp19 9 ilaldlnpsdknlvltGGaDknvvlfdresekvlatlkghtkkvtavafhpsedvlvsasaDktvrvwkkeeketaatlkkhkaevtslsvhptgd 104 i++l+++p d++l++t+ D+++ ++d ++ + tl+gh v v f p+++ +vs+s+Dktv+vw++ ++++++t+ +h+++v +++ ++tg+ FUN_001898-T1 192 IRSLTFSP-DSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGS 286 77889997.579************************************************************************************ PP WD40_Prp19 105 ylvsaskDgtwalh 118 +vs+s+D+++ ++ FUN_001898-T1 287 KIVSVSDDKSVIVY 300 *********99876 PP >> Beta-prop_THOC3 THOC3 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.9 2.4 1.3e-21 4.9e-19 1 124 [. 14 141 .. 14 150 .. 0.90 2 ! 68.6 0.0 1.5e-21 5.9e-19 151 246 .. 127 222 .. 127 227 .. 0.94 3 ! 53.5 1.2 5.9e-17 2.3e-14 164 241 .. 224 301 .. 219 303 .. 0.94 Alignments for each domain: == domain 1 score: 68.9 bits; conditional E-value: 1.3e-21 Beta-prop_THOC3 1 hkkkvhsvawsa...dGk.rLasgsaDktvrvwnleksklsketelkghtdsVeqlawspthpdllatassDktvrlWdvrtgkstatvkt.kg 89 h++++++vaw dG+ +++g++D +v+ w + ++kl+ +++gh+ V ++ ++ t +l a++s D+ +r+Wd+++gk+++ +++ + FUN_001898-T1 14 HEDSIWTVAWGTsdkDGTeNIVTGAVDDMVKCWRWTEDKLHLRFNFEGHQLGVVSVDVNLTG-TLAASSSLDSHIRIWDLESGKQLKAIDCgPV 106 899*******8622245337*********************9*****************997.6999***********************7477 PP Beta-prop_THOC3 90 eninlawspdGktiavgskddtvslidvrtgkvkk 124 +++++a+spd ++ia+gs ++li v++gk ++ FUN_001898-T1 107 DTWTVAFSPDSRFIATGSHAGKINLIGVESGKKES 141 889**************************998765 PP == domain 2 score: 68.6 bits; conditional E-value: 1.5e-21 Beta-prop_THOC3 151 gtvevlsypsleevktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvsFShdGkllAsasedktidiasvet 244 g+++++ ++s+++ l+ + ++++a +p+g+y+A G+ D +++++Dl++++ l+tl+++ p+rs+ FS+d++ll +as+d++i+i++v+ FUN_001898-T1 127 GKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQH 220 56788888999999999999999*********************************************************************98 PP Beta-prop_THOC3 245 ge 246 + FUN_001898-T1 221 AN 222 76 PP == domain 3 score: 53.5 bits; conditional E-value: 5.9e-17 Beta-prop_THOC3 164 vktlkahtsnclcvafdpkgrylAvGsaDalvslWDleeliclrtltrlespvrsvsFShdGkllAsasedktidias 241 tl++h s++l v+f p++++++++s+D++v++WD+ + +c++t+ +++ +v+ v+++ G+ ++s s+dk + +++ FUN_001898-T1 224 AGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 56899********************************************************************99877 PP >> WD40 WD domain, G-beta repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.8 0.00031 0.12 6 38 .. 10 46 .. 5 47 .. 0.79 2 ! 27.1 0.2 1.5e-08 5.9e-06 5 39 .] 57 91 .. 53 91 .. 0.94 3 ! 17.5 0.0 1.6e-05 0.0064 15 37 .. 109 131 .. 95 132 .. 0.84 4 ! 19.6 0.0 3.7e-06 0.0014 15 39 .] 151 175 .. 144 175 .. 0.94 5 ! 43.5 0.0 9.7e-14 3.8e-11 1 39 [] 179 217 .. 179 217 .. 0.97 6 ! 40.1 2.5 1.1e-12 4.4e-10 4 39 .] 224 259 .. 221 259 .. 0.94 7 ! 28.5 0.2 5.3e-09 2.1e-06 2 39 .] 264 301 .. 263 301 .. 0.96 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00031 WD40 6 tlkgHtsgVtsla...fspdgsl....lasgsdDgtvklW 38 ++H+++++++a + +++g+ D vk+W FUN_001898-T1 10 QDQAHEDSIWTVAwgtSDK---DgtenIVTGAVDDMVKCW 46 5579*9*******555444...4555************** PP == domain 2 score: 27.1 bits; conditional E-value: 1.5e-08 WD40 5 rtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++gH+ gV s++ + +g+l as+s D+++++Wd FUN_001898-T1 57 FNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWD 91 579***99**************************9 PP == domain 3 score: 17.5 bits; conditional E-value: 1.6e-05 WD40 15 tslafspdgsllasgsdDgtvkl 37 +++afspd++++a+gs+ g++ l FUN_001898-T1 109 WTVAFSPDSRFIATGSHAGKINL 131 89**************9988865 PP == domain 4 score: 19.6 bits; conditional E-value: 3.7e-06 WD40 15 tslafspdgsllasgsdDgtvklWd 39 +s+a+spdg+++a+g+ Dg + ++d FUN_001898-T1 151 MSIAYSPDGHYIACGAIDGIINIFD 175 699********************98 PP == domain 5 score: 43.5 bits; conditional E-value: 9.7e-14 WD40 1 gkllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 gkll+tl+gH +++sl+fspd++ll+++sdD+++k++d FUN_001898-T1 179 GKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYD 217 689*******999*************************9 PP == domain 6 score: 40.1 bits; conditional E-value: 1.1e-12 WD40 4 lrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 +tl+gH s+V +++f+pd+++++s+s D+tvk+Wd FUN_001898-T1 224 AGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWD 259 679****999****************99*******9 PP == domain 7 score: 28.5 bits; conditional E-value: 5.3e-09 WD40 2 kllrtlkgHtsgVtslafspdgsllasgsdDgtvklWd 39 ++++t+ H++ V++++++ +gs ++s sdD++v +++ FUN_001898-T1 264 QCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 8********999***********************997 PP >> Beta-prop_WDR3_1st WDR3 first beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.0 1.6 8.1e-15 3.1e-12 68 180 .. 12 130 .. 3 134 .. 0.87 2 ! 135.8 0.6 4.7e-42 1.8e-39 13 183 .. 131 301 .. 125 302 .. 0.96 Alignments for each domain: == domain 1 score: 47.0 bits; conditional E-value: 8.1e-15 Beta-prop_WDR3_1st 68 ngHksavtalaf...dkdg.srLasGskDtdiivwDvvaeaglfrL..kgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlv 152 ++H+ +++++a+ dkdg +++++G+ D + w ++++ r+ +gH+ v sv + ++++ +ssS D+ i++Wdle+++++k + FUN_001898-T1 12 QAHEDSIWTVAWgtsDKDGtENIVTGAVDDMVKCWRWTEDKLHLRFnfEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAID 102 57999999999844445552479***************99988775227****************************************** PP Beta-prop_WDR3_1st 153 ghrsevwslalskdekllvtgssdselr 180 w++a+s+d+++++tgs+ +++ FUN_001898-T1 103 CGPVDTWTVAFSPDSRFIATGSHAGKIN 130 **********************988876 PP == domain 2 score: 135.8 bits; conditional E-value: 4.7e-42 Beta-prop_WDR3_1st 13 vWdlkkgekvatlegeksevtalaaspdgkklavGyadgsirlwdlesgelevtfngHksavtalafdkdgsrLasGskDtdiivwDvvae 103 + +++g+k + l++ + ++a spdg+ +a+G dg i+++dl++g+l t++gH + +l+f++d + L+++s D++i ++Dv + FUN_001898-T1 131 LIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHA 221 556788888899999999999********************************************************************** PP Beta-prop_WDR3_1st 104 aglfrLkgHkdqvtsvafleekkvlvssSkDtliklWdletqhcvktlvghrsevwslalskdekllvtgssdselrvwk 183 + +L+gH + v v+f++++++ vssS+D+++k+Wd +++cv+t+ +h+ +vw ++ ++ ++ +v+ s+d+++ v++ FUN_001898-T1 222 NLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 ****************************************************************************9996 PP >> Beta-prop_WDR3_2nd WDR3 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.6 0.00051 0.2 73 109 .. 8 48 .. 3 52 .. 0.77 2 ! 28.3 0.1 3.5e-09 1.4e-06 162 241 .. 50 129 .. 48 132 .. 0.93 3 ! 114.7 3.1 1.6e-35 6.3e-33 66 286 .. 91 300 .. 91 302 .. 0.94 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00051 Beta-prop_WDR3_2nd 73 letieahegavwsvaltp.de...kglvtggaDkkvkfwef 109 +++ +ahe+++w+va + d+ +++vtg+ D +vk+w FUN_001898-T1 8 FKQDQAHEDSIWTVAWGTsDKdgtENIVTGAVDDMVKCWRW 48 56779*********9754233223689************86 PP == domain 2 score: 28.3 bits; conditional E-value: 3.5e-09 Beta-prop_WDR3_2nd 162 lDtlkfflslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkv 241 +D l++ +++ Gh+l v+s+d+ ++l +++s D i+iw l+ G + k++ +vaf p + + + ++ +k+ FUN_001898-T1 50 EDKLHLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKI 129 68999999********************************************999999999****999999998888877 PP == domain 3 score: 114.7 bits; conditional E-value: 1.6e-35 Beta-prop_WDR3_2nd 66 dlasaelletieahegavwsvaltpdekglvtggaDkkvkfwefelveeeeskakklslkhtrtlklsddvlcvkvspdkkllavallDst 156 dl+s+++l++i+ + w+va +pd++ + tg+ k+++ +e ++e+ l + ++ +++ +spd++++a +D FUN_001898-T1 91 DLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKINLIGVESGKKES------ALDTRGKFT-----MSIAYSPDGHYIACGAIDGI 170 789************************************999888776544......333333444.....4789**************** PP Beta-prop_WDR3_2nd 157 vkvfflDtlkfflslYGhklPvlsldissDsklivtgsaDknikiwGldfGDchkslfahddsvmsvafvpktHylfsagkdkkvkyWDad 247 + +f l t k+ ++l Gh +P+ sl +s Ds+l++t+s D iki+ +++ ++ +l +h + v+ v+f p + ++ s++ dk+vk WDa FUN_001898-T1 171 INIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAG 261 ************************************************************************999**************** PP Beta-prop_WDR3_2nd 248 kfekiqtleghagevwalavsskgkfvvsashDksiRlw 286 + +++qt+ h+++vw + +g+ +vs+s Dks+ ++ FUN_001898-T1 262 SRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVY 300 ***********************************9888 PP >> WD40_WDHD1_1st WDHD1 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.3 0.2 2.6e-11 9.9e-09 99 170 .. 32 105 .. 19 108 .. 0.87 2 ! 35.8 0.0 1.8e-11 6.9e-09 91 168 .. 110 187 .. 105 190 .. 0.95 3 ! 62.0 0.2 1.8e-19 7e-17 87 166 .. 190 269 .. 187 276 .. 0.95 4 ? 5.5 0.1 0.03 12 3 33 .. 271 301 .. 269 303 .. 0.65 Alignments for each domain: == domain 1 score: 35.3 bits; conditional E-value: 2.6e-11 WD40_WDHD1_1st 99 kllaagseDftikvvsvedss..kqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkvlp 170 + ++ g+ D ++k+ ++ + +++egh+ v sv+++ +g + aSss D +++iWd+es++++k++++ p FUN_001898-T1 32 ENIVTGAVDDMVKCWRWTEDKlhLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGP 105 46899***********9777522457999****************************************99866 PP == domain 2 score: 35.8 bits; conditional E-value: 1.8e-11 WD40_WDHD1_1st 91 hialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktlkv 168 ++a+s+d +++a gs +i+++ ve ++k+ l+ + +s+a++p g+y+a ++DG ++i+d+++++ ++tl+ FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEG 187 699*********************************************************************999875 PP == domain 3 score: 62.0 bits; conditional E-value: 1.8e-19 WD40_WDHD1_1st 87 apvthialskdgkllaagseDftikvvsvedsskqktleghkapvlsvaldpkgeylaSsscDGtvkiWdieskecvktl 166 p++++++s+d +ll+ +s+D +ik+++v+ + + tl+gh + vl v+++p + + +Sss+D tvk+Wd s++cv+t+ FUN_001898-T1 190 MPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTF 269 699******************************9*******************************************997 PP == domain 4 score: 5.5 bits; conditional E-value: 0.03 WD40_WDHD1_1st 3 aHseGhtdvcysedgkkliTcGsDgdvriwe 33 Hs+ v y+++g+k++++ +D v +++ FUN_001898-T1 271 QHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 5666666677777777777777777777665 PP >> WD40_MABP1-WDR62_2nd MABP1/WDR62 second WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 4.9e-06 0.0019 175 304 .. 14 139 .. 2 146 .. 0.72 2 ! 38.0 0.0 3.4e-12 1.3e-09 232 338 .. 112 215 .. 104 216 .. 0.89 3 ! 41.8 0.0 2.4e-13 9.2e-11 91 185 .. 150 240 .. 128 244 .. 0.85 4 ! 45.6 2.5 1.6e-14 6.2e-12 240 339 .. 204 300 .. 203 302 .. 0.91 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 4.9e-06 WD40_MABP1-WDR62_2nd 175 hsssitavkfae..eeeklkliscgaDksilfrkaqktkegvefsrehhvvekttlydmevdaskklvavacqDrnirvynvssgkqkk 261 h si +v + + ++++ ++++ ++D + + +++k +++f+ e h + ++v+ + +l+a ++ D +ir+++++sgkq k FUN_001898-T1 14 HEDSIWTVAWGTsdKDGTENIVTGAVDDMVKCWRWTEDKLHLRFNFEGHQ---LGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLK 99 66677766665411344566777777777777666666667777776664...456678889999999999999999999999999998 PP WD40_MABP1-WDR62_2nd 262 sfkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGec 304 ++ + v++ p + ++at + ++ ++ esG+ FUN_001898-T1 100 AIDCGPVDT---WTVAFSPDSRFIATGSHAGKINLIGVESGKK 139 888877765...4578888899999999988899888888876 PP == domain 2 score: 38.0 bits; conditional E-value: 3.4e-12 WD40_MABP1-WDR62_2nd 232 evdaskklvavacqDrnirvynvssgkqkksfkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGecvatvfGhseivtglkF 320 + +++++++a++++ +i + v+sgk++ ++ + ++ p g y+a + d + i+d+++G+++ t+ Gh+ + +l F FUN_001898-T1 112 AFSPDSRFIATGSHAGKINLIGVESGKKESALDTR---GKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTF 197 567789999******************99887543...33568999******************************************* PP WD40_MABP1-WDR62_2nd 321 tedcrhlisvsgDsCifv 338 + d + li++s D i + FUN_001898-T1 198 SPDSQLLITASDDNHIKI 215 *************98765 PP == domain 3 score: 41.8 bits; conditional E-value: 2.4e-13 WD40_MABP1-WDR62_2nd 91 vRvlkvspdgkhlasGDrsGniriydletleellkieahdsevlcleyskpetglkllasasRDRlihvfdvekdysllqtlddhsssi 179 ++ spdg+ +a+G G i i+dl+t + l+++e h + +l +s +ll +as D i+++dv++ +l+ tl+ h s + FUN_001898-T1 150 TMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPD---SQLLITASDDNHIKIYDVQH-ANLAGTLSGHGSWV 234 457889******************************************985...68***************975.699*********99 PP WD40_MABP1-WDR62_2nd 180 tavkfa 185 v f FUN_001898-T1 235 LGVSFC 240 999986 PP == domain 4 score: 45.6 bits; conditional E-value: 1.6e-14 WD40_MABP1-WDR62_2nd 240 vavacqDrnirvynvssgkqkksfkgsqsedgtllkvqlDpsglyvatscsdknlsildfesGecvatvfGhseivtglkFtedcrhli 328 +++a++D +i++y+v++++ ++ g + +l v++ p +++++s+sdk+++++d s +cv t + hs+ v g+k+ + + +++ FUN_001898-T1 204 LITASDDNHIKIYDVQHANLAGTLSGHG---SWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIV 289 579************9988776666543...4699****************************************************** PP WD40_MABP1-WDR62_2nd 329 svsgDsCifvW 339 svs D + v+ FUN_001898-T1 290 SVSDDKSVIVY 300 ******99997 PP >> WD40_CDC20-Fz CDC20/Fizzy WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 1.6 2.6e-08 1e-05 85 171 .. 7 99 .. 2 105 .. 0.84 2 ! 9.0 0.0 0.0028 1.1 56 89 .. 110 143 .. 106 147 .. 0.88 3 ! 89.0 0.3 1.2e-27 4.6e-25 47 193 .. 143 289 .. 135 303 .. 0.90 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 2.6e-08 WD40_CDC20-Fz 85 klrtleghssrvgalaw......nenllssGsrdgkilhhDvrtkelevvktlkahkqevcglkwspdgrllAsGgndntvkiwdlrslspll 171 ++++ ++h++++ ++aw ++++++G d + ++ + +l+ ++++h+ v +++++ +g+l As++ d+ ++iwdl+s ++l+ FUN_001898-T1 7 CFKQDQAHEDSIWTVAWgtsdkdGTENIVTGAVDDMVKCWRWTEDKLHLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLK 99 5677789999999999976543223459*************99999999999********************************998766655 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0028 WD40_CDC20-Fz 56 svkwsedgelLavGtssgevelwdvekkkklrtl 89 v++s+d++++a+G++ g+++l+ ve++kk + l FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVESGKKESAL 143 699***********************99987665 PP == domain 3 score: 89.0 bits; conditional E-value: 1.2e-27 WD40_CDC20-Fz 47 lseesdyvtsvkwsedgelLavGtssgevelwdvekkkklrtleghssrvgalaw..nenllssGsrdgkilhhDvrtkelevvktlkahkqevcg 140 l++++++ +s+++s+dg+++a+G +g ++++d +++k l+tlegh+ + +l++ +++ll++ s+d++i ++Dv+ ++l tl++h + v g FUN_001898-T1 143 LDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFspDSQLLITASDDNHIKIYDVQHANLA--GTLSGHGSWVLG 236 45678999**********************************************9545667******************865..79********** PP WD40_CDC20-Fz 141 lkwspdgrllAsGgndntvkiwdlrslspllkltehkaavkAlaWcpwkkslL 193 +++ pd++++ s+++d+tvk+wd+ s + ++++ +h+ +v ++++ + ++++ FUN_001898-T1 237 VSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIV 289 *****************************************999998777665 PP >> Beta-prop_EML_2 Echinoderm microtubule-associated protein second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.2 0.0 3.7e-12 1.4e-09 2 115 .. 23 139 .. 19 149 .. 0.90 2 ! 70.2 0.1 6.1e-22 2.4e-19 42 160 .. 150 267 .. 138 274 .. 0.93 3 ! 8.8 0.0 0.0035 1.3 1 27 [. 276 302 .. 276 303 .. 0.96 Alignments for each domain: == domain 1 score: 38.2 bits; conditional E-value: 3.7e-12 Beta-prop_EML_2 2 wGLathpsepqfvTagdDktvrlWdlekkklvakvklek...earsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspd 92 wG + + ++ +vT+ D +v +W+ + kl + ++e + sv+++ g+l a + d ++ ++d e+++++++++ +++fspd FUN_001898-T1 23 WGTSDKDGTENIVTGAVDDMVKCWRWTEDKLHLRFNFEGhqlGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPD 116 666667778899***********************9987333589************************************************* PP Beta-prop_EML_2 93 gklLavgshdnkiylYdvskkyk 115 ++++a gsh +ki+l v+++ k FUN_001898-T1 117 SRFIATGSHAGKINLIGVESGKK 139 ***************99987544 PP == domain 2 score: 70.2 bits; conditional E-value: 6.1e-22 Beta-prop_EML_2 42 arsvafspdgkllavGlkdGsvlvldaetleevvevkdrkeaisdikfspdgklLavgshdnkiylYdvskkykkvgklkghssfithlDwsed 135 + s+a+spdg+++a+G dG + ++d +t++ +++++ + +i+ ++fspd++lL +s dn+i++Ydv ++ + +g+l+gh s ++ + + d FUN_001898-T1 150 TMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDV-QHANLAGTLSGHGSWVLGVSFCPD 242 579*****************************************************************9.67999******************* PP Beta-prop_EML_2 136 skylqsnsgdyellfwdaktgkqvt 160 +++ s+s+d + +wda + + v+ FUN_001898-T1 243 NTHFVSSSSDKTVKVWDAGSRQCVQ 267 *****************98876655 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0035 Beta-prop_EML_2 1 lwGLathpsepqfvTagdDktvrlWdl 27 +wG+ + + +++v+++dDk+v+++++ FUN_001898-T1 276 VWGVKYNATGSKIVSVSDDKSVIVYNC 302 7***********************996 PP >> WDR55 WDR55 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.1 1.1e-06 0.00041 20 121 .. 32 131 .. 13 132 .. 0.91 2 ! 27.1 0.0 6.9e-09 2.7e-06 11 91 .. 109 185 .. 98 186 .. 0.90 3 ! 72.3 0.3 1.2e-22 4.6e-20 9 165 .. 149 301 .. 145 303 .. 0.93 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 1.1e-06 WDR55 20 diiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllvidenllatGdd 115 + i++g +d v+++++++++ + ++e h+ + +v + G+ s s D i++ d+e+gk +k i+ ++ d++++atG FUN_001898-T1 32 ENIVTGAVDDMVKCWRWTEDK--LHLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSH 125 56899************9755..678899*******************************************99999999999999********** PP WDR55 116 dGtvkl 121 G ++l FUN_001898-T1 126 AGKINL 131 *99976 PP == domain 2 score: 27.1 bits; conditional E-value: 6.9e-09 WDR55 11 vdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkki 91 +++f+P++ +ia+g+ G++ l + ++e l++ k + ++++s dG+ + + + D i+++d++tgkl++++ FUN_001898-T1 109 WTVAFSPDSRFIATGSHAGKINLIGVESGKKE----SALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTL 185 689*********************99986544....56789999*********************************9876 PP == domain 3 score: 72.3 bits; conditional E-value: 1.2e-22 WDR55 9 lvvdisfhPsediiavgtidGdvllykysneenenkellslehhkkscraveFsedGkklfsvskDksiavldvetgklkkkiekahespiysllv 104 + ++i+++P+ + ia+g idG + ++ ++ k l++le h +r+++Fs d + l+++s D+ i+++dv++ +l +++ + + + FUN_001898-T1 149 FTMSIAYSPDGHYIACGAIDGIINIFDLTTG----KLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFC 240 6799***********************9973....589*********************************************9766666666666 PP WDR55 105 idenllatGdddGtvklWDlRkkkavmelkehedyisdlvvdeekklLlatsgdGtltvfn 165 d++ +++ d tvk+WD ++++v ++ +h+d + + ++ + ++++s d ++ v+n FUN_001898-T1 241 PDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 788899*************************************************999998 PP >> WD40_Gbeta G protein beta WD-40 repeat protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.2 1.9e-07 7.4e-05 155 253 .. 32 132 .. 27 138 .. 0.87 2 ! 92.9 2.6 7e-29 2.7e-26 60 253 .. 110 300 .. 106 302 .. 0.95 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.9e-07 WD40_Gbeta 155 nqivtssgdtt..calwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsdda 248 ++ivt + d c w + + + f gh v+s+ + + l s + d+ +++wd+ g +++ d ++af p+ + +atgs FUN_001898-T1 32 ENIVTGAVDDMvkCWRWTEDKLHLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAG 127 5899988886512666677777788999******************************************999********************987 PP WD40_Gbeta 249 tcrlf 253 l+ FUN_001898-T1 128 KINLI 132 77665 PP == domain 2 score: 92.9 bits; conditional E-value: 7e-29 WD40_Gbeta 60 amhwgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnfvacggldnicsiynlktregnvrvsrelaghtgylsccrflddn 155 ++ ++ dsr++ + s+ gk+ + + +k a+ r + m+ ay+p g ++acg +d i i++l t ++ + l gh+ + f d FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTG----KLLHTLEGHAMPIRSLTFSPDS 201 567889*************************************************************984....68899*************9998 PP WD40_Gbeta 156 q.ivtssgdttcalwdietgqqttvfvghtgdvmslslapdtrlfvsgacdasaklwdvreglcrqtfighesdinaiaffpngealatgsddatc 250 q ++t+s d ++d++ + +++gh v+ +s++pd fvs + d ++k+wd c qtf h ++ + + g+ +++ sdd ++ FUN_001898-T1 202 QlLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSV 297 835899***************************************************************************************997 PP WD40_Gbeta 251 rlf 253 ++ FUN_001898-T1 298 IVY 300 665 PP >> EIF3I EIF3I # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 2.5 0.19 72 50 83 .. 13 50 .. 10 58 .. 0.76 2 ! 72.3 0.0 1.3e-22 5.2e-20 48 220 .. 59 221 .. 56 224 .. 0.88 3 ! 25.4 1.4 2.6e-08 1e-05 46 115 .. 225 295 .. 221 302 .. 0.90 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.19 EIF3I 50 GheGavwsidv....dsettllvtgsadntvklWdvet 83 he ++w++ + t+++vtg+ d +vk W+ ++ FUN_001898-T1 13 AHEDSIWTVAWgtsdKDGTENIVTGAVDDMVKCWRWTE 50 688899998752221345899*************8765 PP == domain 2 score: 72.3 bits; conditional E-value: 1.3e-22 EIF3I 48 yeGheGavwsidvdsettllvtgsadntvklWdvetGkelktlet.ktavrsvefsesgkllllvtdkvmgkkseivvldirdeeeeeeeepvlki 142 +eGh+ v s+dv+ + tl++++s d+++++Wd+e+Gk+lk +++ ++ +v+fs++++ +++ ++ ++i+++ +++ ++e+ + FUN_001898-T1 59 FEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCgPVDTWTVAFSPDSRFIAT-----GSHAGKINLIGVESGKKES------AL 143 99******************************************83467889999999887764.....4567899999998765543......34 PP EIF3I 143 eveeskvtvalwsaldktiitghedgeiskydlktgeklksvkehekqitdlqlskdktylitaskDktaklldvetl 220 ++ + ++++++s +++i g dg i+ +dl+tg+ l++ + h + i+ l +s+d+++litas D++ k++dv++ FUN_001898-T1 144 DTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHA 221 44556667899***************************************************************9875 PP == domain 3 score: 25.4 bits; conditional E-value: 2.6e-08 EIF3I 46 GtyeGheGavwsidvdsettllvtgsadntvklWdvetGkelktl.etktavrsvefsesgkllllvtdkv 115 Gt++Gh v + + t++v++s+d+tvk+Wd + ++++t+ +++ +v v+++ +g++++ v d++ FUN_001898-T1 225 GTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFyQHSDQVWGVKYNATGSKIVSVSDDK 295 9******************************************982455689************9998764 PP >> Beta-prop_WDR36-Utp21_2nd WDR36/Utp21 second beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.8 1.4e-09 5.3e-07 149 299 .. 7 165 .. 2 168 .. 0.84 2 ! 42.2 0.0 2.2e-13 8.3e-11 181 274 .. 129 223 .. 123 227 .. 0.83 3 ! 36.0 1.6 1.6e-11 6.4e-09 217 302 .. 208 294 .. 207 301 .. 0.89 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 1.4e-09 Beta-prop_WDR36-Utp21_2nd 149 sygkekahkkavrGvav....dalnqvvitagadkklkfwkfkskklletlkle...asisklvlhressllavalddfsilvv 225 ++ +++ah++++ va ++ ++ ++t++ d +k w+ + kl +++e + ++ ++ +l a + d i++ FUN_001898-T1 7 CFKQDQAHEDSIWTVAWgtsdKDGTENIVTGAVDDMVKCWRWTEDKLHLRFNFEghqLGVVSVDVNLTGTLAASSSLDSHIRIW 90 5678999999988776521113456789****************999988876511145677778888999999999******* PP Beta-prop_WDR36-Utp21_2nd 226 DidtrrvvRkfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvflve.saatslslsptgdfLata 299 D+++ + + + ++fspd+r++ t s i + sgk ++ ++ + ++s++ sp g+++a FUN_001898-T1 91 DLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRgKFTMSIAYSPDGHYIACG 165 ************9999999******************************999998857889**********9975 PP == domain 2 score: 42.2 bits; conditional E-value: 2.2e-13 Beta-prop_WDR36-Utp21_2nd 181 lkfwkfkskklletlkle.asisklvlhressllavalddfsilvvDidtrrvvRkfsghknritDltfspdarWlitasmDst 263 +++ ++s k+ ++l+ + + ++++ + +a+ d i+++D++t ++ +++gh i+ ltfspd++ litas D FUN_001898-T1 129 INLIGVESGKKESALDTRgKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNH 212 555555565555566554134456788899999*************************************************** PP Beta-prop_WDR36-Utp21_2nd 264 irtwdlpsgkl 274 i+++d++ ++l FUN_001898-T1 213 IKIYDVQHANL 223 ******99887 PP == domain 3 score: 36.0 bits; conditional E-value: 1.6e-11 Beta-prop_WDR36-Utp21_2nd 217 lddfsilvvDidtrrvvRkfsghknritDltfspdarWlitasmDstirtwdlpsgkliDvfl.vesaatslslsptgdfLata 299 dd i+++D++ +++ ++sgh + + ++f pd ++++s+D t+++wd s + + +f ++ + ++ +tg ++++ FUN_001898-T1 208 SDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYqHSDQVWGVKYNATGSKIVSV 291 799*********************************************************997256788899999999888876 PP Beta-prop_WDR36-Utp21_2nd 300 hvd 302 d FUN_001898-T1 292 SDD 294 554 PP >> Beta-prop_CAF1B_HIR1 CAF1B/HIR1 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 1.2 0.00013 0.05 124 210 .. 9 101 .. 3 108 .. 0.68 2 ! 24.2 0.0 5.2e-08 2e-05 132 208 .. 107 183 .. 98 186 .. 0.94 3 ! 52.3 0.1 1.5e-16 5.8e-14 123 210 .. 182 269 .. 180 273 .. 0.95 4 ? 5.0 0.2 0.036 14 62 97 .. 265 300 .. 262 303 .. 0.58 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00013 Beta-prop_CAF1B_HIR1 124 kvlrGhledvyDlswspds....kklisgsvDntailWdvekgkkla..ilkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkv 206 k + h + ++ ++w +++ +++++g+vD+ + W ++ k ++ h+ v +v + ++++ a+ s D ++ri+d+++ k FUN_001898-T1 9 KQDQAHEDSIWTVAWGTSDkdgtENIVTGAVDDMVKCWRWTEDKLHLrfNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQ 97 55567888888888876541122578999999988888877665443004555666666666667788888888899999999888877 PP Beta-prop_CAF1B_HIR1 207 varv 210 ++ + FUN_001898-T1 98 LKAI 101 6655 PP == domain 2 score: 24.2 bits; conditional E-value: 5.2e-08 Beta-prop_CAF1B_HIR1 132 dvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkvva 208 d + +++spds+++ +gs ++ l ve gkk + l+ + +f ++a+ P ++y+a + D ++ ifd++t k+++ FUN_001898-T1 107 DTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLH 183 67789*******************************************************************99887 PP == domain 3 score: 52.3 bits; conditional E-value: 1.5e-16 Beta-prop_CAF1B_HIR1 123 lkvlrGhledvyDlswspdskklisgsvDntailWdvekgkklailkdhkgfvqgvawdPknqyvatlssDrslrifdiktkkvvarv 210 l++l Gh + l++spds+ li++s Dn + ++dv++++ l+ h ++v gv+++P n+ +++ ssD++++++d+ ++++v+ FUN_001898-T1 182 LHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTF 269 5789********************************************************************************9876 PP == domain 4 score: 5.0 bits; conditional E-value: 0.036 Beta-prop_CAF1B_HIR1 62 lladltrhqkavnvvrfspsgelLasgdDesviiiW 97 ++ + +h+ v v++ +g+ + s +D+ +i++ FUN_001898-T1 265 CVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVY 300 445555666666666666666666666666666655 PP >> Beta-prop_WDR90_POC16_2nd WDR90/POC16, second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.9 0.0 2.3e-09 8.8e-07 10 92 .. 79 161 .. 68 161 .. 0.86 2 ! 36.8 0.0 8.9e-12 3.4e-09 40 111 .. 151 222 .. 142 226 .. 0.94 3 ! 21.1 0.6 5.5e-07 0.00021 232 285 .. 242 293 .. 229 300 .. 0.83 Alignments for each domain: == domain 1 score: 28.9 bits; conditional E-value: 2.3e-09 Beta-prop_WDR90_POC16_2nd 10 atvseDetiriWdldtlqqlydfsaseeaPcavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvt.glvfspdgey 92 a s D+ iriWdl++ +ql + +vaf P ++ +a G++ G + + ve+ + rgk t ++++spdg+y FUN_001898-T1 79 ASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESAL-DTRGKFTmSIAYSPDGHY 161 56789*****************999888889**************************99876655.5667664389*****987 PP == domain 2 score: 36.8 bits; conditional E-value: 8.9e-12 Beta-prop_WDR90_POC16_2nd 40 cavafhPskqvfacGfssGvvrvfsveatsllaehkqhrgkvtglvfspdgeylysacslGslalydaseee 111 +++a+ P + +acG +G++ +f++++ +ll + h + +l+fspd+++l +a+ + +yd+++ + FUN_001898-T1 151 MSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHAN 222 78*****************************************************************98865 PP == domain 3 score: 21.1 bits; conditional E-value: 5.5e-07 Beta-prop_WDR90_POC16_2nd 232 edarylltagdkvikvwdysmkldinfqvfiGhsekvqqvaftpdqqevlsvGd 285 ++++++ +++dk++kvwd + + +q f hs++v v++ + ++++sv d FUN_001898-T1 242 DNTHFVSSSSDKTVKVWDAGSR--QCVQTFYQHSDQVWGVKYNATGSKIVSVSD 293 3455666789********8776..56899***********************87 PP >> ANAPC4_WD40 Anaphase-promoting complex subunit 4 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.2 0.0011 0.41 20 79 .. 44 104 .. 19 110 .. 0.82 2 ! 11.7 0.0 0.00086 0.33 44 77 .. 111 144 .. 106 151 .. 0.88 3 ! 22.5 0.0 3.5e-07 0.00014 42 78 .. 151 187 .. 143 191 .. 0.89 4 ! 18.8 0.0 5.2e-06 0.002 37 76 .. 188 227 .. 184 232 .. 0.88 5 ! 11.3 0.1 0.0012 0.45 37 89 .. 230 282 .. 225 284 .. 0.90 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0011 ANAPC4_WD40 20 llkRlnwqrvwkl.seekedsevtslaWkpdGklLavaysdgevrlldvesgklvhslsak 79 + R ++ + e++++ v s+ + G+l a + d+++r+ d esgk ++ ++++ FUN_001898-T1 44 KCWRWTEDKLHLRfNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCG 104 555555555443335578899999999*****************************99987 PP == domain 2 score: 11.7 bits; conditional E-value: 0.00086 ANAPC4_WD40 44 laWkpdGklLavaysdgevrlldvesgklvhsls 77 +a++pd +++a + + g+++l+ vesgk + l+ FUN_001898-T1 111 VAFSPDSRFIATGSHAGKINLIGVESGKKESALD 144 799************************9776665 PP == domain 3 score: 22.5 bits; conditional E-value: 3.5e-07 ANAPC4_WD40 42 tslaWkpdGklLavaysdgevrlldvesgklvhslsa 78 s+a++pdG+ +a + dg ++++d +gkl+h+l+ FUN_001898-T1 151 MSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEG 187 589******************************9875 PP == domain 4 score: 18.8 bits; conditional E-value: 5.2e-06 ANAPC4_WD40 37 edsevtslaWkpdGklLavaysdgevrlldvesgklvhsl 76 + ++sl ++pd +lL+ a +d++++++dv+ ++l+ +l FUN_001898-T1 188 HAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTL 227 56789***************************99987665 PP == domain 5 score: 11.3 bits; conditional E-value: 0.0012 ANAPC4_WD40 37 edsevtslaWkpdGklLavaysdgevrlldvesgklvhslsaksdkitcleWa 89 ++s v ++++ pd + ++ + sd +v++ d+ s ++v+++ ++sd++ ++++ FUN_001898-T1 230 HGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYN 282 67789999************************************998877765 PP >> Beta-prop_TEP1_2nd TEP-1 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.9 0.3 3.2e-11 1.2e-08 11 182 .. 33 194 .. 18 196 .. 0.84 2 ! 55.9 2.0 1.3e-17 4.9e-15 84 203 .. 183 301 .. 178 303 .. 0.90 Alignments for each domain: == domain 1 score: 34.9 bits; conditional E-value: 3.2e-11 Beta-prop_TEP1_2nd 11 vlvsGaedgslqvWkleesssqcllllkahqkavlgl..alsqkllasasedltvrlWskelltqpekaeslsslsvlrghtgavtccsfs 99 +v+Ga d +++W+ +e +++ ++ +++hq v+++ l+ l as+s d +r+W e+ q + + ++ v +fs FUN_001898-T1 33 NIVTGAVDDMVKCWRWTEDKLHLRFNFEGHQLGVVSVdvNLTGTLAASSSLDSHIRIWDLESGKQ---LKAIDCGPV------DTWTVAFS 114 68********************************9861156789**************9888743...345666554......234579** PP Beta-prop_TEP1_2nd 100 ldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkddllvscss.dGsvglWdiekeqrlgkflGhqsavsa 182 +d + +atg++ ++ + v+ k s l + + a+ d+ ++c + dG + ++d+++++ l+++ Gh ++ + FUN_001898-T1 115 PDSRFIATGSHAGKINLIGVESGKK----ESALDTRGKFTMSIAYSPDGHYIACGAiDGIINIFDLTTGKLLHTLEGHAMPIRS 194 ********************99776....4556667789999******999998644*********************999876 PP == domain 2 score: 55.9 bits; conditional E-value: 1.3e-17 Beta-prop_TEP1_2nd 84 svlrghtgavtccsfsldGgllatggrdrsllcWdvrvpkaPvlirsllachrdWvtgcaWtkdd.llvscssdGsvglWdiekeqrlgkf 173 ++l gh ++ +fs+d +ll t++ d+ + ++dv++++ + l+ h Wv g ++ d+ +vs+ssd +v +Wd ++q +++f FUN_001898-T1 183 HTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHAN----LAGTLSGHGSWVLGVSFCPDNtHFVSSSSDKTVKVWDAGSRQCVQTF 269 6799*********************************954....4556789**********9776269*********************** PP Beta-prop_TEP1_2nd 174 lGhqsavsavv..aveehvvsvgrdGllkvWd 203 h v +v a + ++vsv+ d +++v++ FUN_001898-T1 270 YQHSDQVWGVKynATGSKIVSVSDDKSVIVYN 301 *******999544899**********999987 PP >> Beta-prop_WDR36-Utp21_1st WDR36/Utp21 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.3 0.0 2.9e-18 1.1e-15 87 263 .. 43 216 .. 31 219 .. 0.83 2 ! 17.3 0.2 9e-06 0.0035 174 263 .. 213 300 .. 212 302 .. 0.87 Alignments for each domain: == domain 1 score: 58.3 bits; conditional E-value: 2.9e-18 Beta-prop_WDR36-Utp21_1st 87 llvwkieteelyteiefseeefeitallhpsTYlnKilvgsk..qGslqlwNirtgkliytfksfksaitaleqspaldvvaig 168 +++w+ ++++l+ +++f+ + ++ ++ l l +s+ + ++++w++++gk + +++ +++ sp +a g FUN_001898-T1 43 VKCWRWTEDKLHLRFNFEG---HQLGVVSVDVNLTGTLAASSslDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATG 123 5666666666666666654...3334444444444445544422689************************************* PP Beta-prop_WDR36-Utp21_1st 169 lasGeivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllv 252 + G+i l+ ++ +++ l++ + si++ Dg+ ++a+g +G i ++dL +++l+h+l + H+ ++ +l+f p+ +ll+ FUN_001898-T1 124 SHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGH-YIACGAIDGIINIFDLTTGKLLHTL-EGHAMPIRSLTFSPDSQLLI 205 ***********************99999*******97.789**********************.57****************** PP Beta-prop_WDR36-Utp21_1st 253 tsgaDNslkew 263 t++ DN++k++ FUN_001898-T1 206 TASDDNHIKIY 216 *********87 PP == domain 2 score: 17.3 bits; conditional E-value: 9e-06 Beta-prop_WDR36-Utp21_1st 174 ivlhnikkdetllklkqeegpvtsisFrtDgepvlatgsssGdialwdLekrrlvhvlrnaHeggvtkleflpgqpllvtsgaD 257 i ++++++ + +l+ + + v +sF+ D+ +++++ss+ ++ +wd +r+ v++ H+ +v ++++ ++ +v+ + D FUN_001898-T1 213 IKIYDVQHANLAGTLSGHGSWVLGVSFCPDN-THFVSSSSDKTVKVWDAGSRQCVQTF-YQHSDQVWGVKYNATGSKIVSVSDD 294 7899999999999999999999999999995.57888889999999**9999999998.6899999999999999999999999 PP Beta-prop_WDR36-Utp21_1st 258 Nslkew 263 s+ ++ FUN_001898-T1 295 KSVIVY 300 888765 PP >> Beta-prop_TEP1_C TEP-1 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.1 0.025 9.7 13 34 .. 32 53 .. 25 64 .. 0.85 2 ! 21.6 0.0 6e-07 0.00023 7 69 .. 70 130 .. 62 133 .. 0.88 3 ? -0.4 0.0 4.2 1.6e+03 15 52 .. 162 200 .. 159 204 .. 0.78 4 ! 13.5 0.0 0.0002 0.078 12 42 .. 201 231 .. 188 245 .. 0.78 5 ! 15.2 2.1 5.7e-05 0.022 14 42 .. 245 273 .. 230 300 .. 0.75 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.025 Beta-prop_TEP1_C 13 dliisAseDrtvKlWdretkkq 34 + i++ + D vK W+ ++ k+ FUN_001898-T1 32 ENIVTGAVDDMVKCWRWTEDKL 53 679************9988876 PP == domain 2 score: 21.6 bits; conditional E-value: 6e-07 Beta-prop_TEP1_C 7 alkltddliisAseDrtvKlWdretkkqvGlFvCeapvlvlevnpnpeseleLvcgDklGkvY 69 +++lt l s+s D+++++Wd e+ kq+ C +pv + +v +p+s ++ g + Gk+ FUN_001898-T1 70 DVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDC-GPVDTWTVAFSPDSR-FIATGSHAGKIN 130 4789999999************************.7******99888755.789999999985 PP == domain 3 score: -0.4 bits; conditional E-value: 4.2 Beta-prop_TEP1_C 15 iisAseDrtvKlWdretkkqvGlFvCea.pvlvlevnpn 52 i + D + + d +t k++ +a p+ +l+ +p FUN_001898-T1 162 IACGAIDGIINIFDLTTGKLLHTLEGHAmPIRSLTFSPD 200 667788999999999999999988887668888877654 PP == domain 4 score: 13.5 bits; conditional E-value: 0.0002 Beta-prop_TEP1_C 12 ddliisAseDrtvKlWdretkkqvGlFvCea 42 ++l+i+As D+++K++d + + G ++ FUN_001898-T1 201 SQLLITASDDNHIKIYDVQHANLAGTLSGHG 231 4689***************999998877665 PP == domain 5 score: 15.2 bits; conditional E-value: 5.7e-05 Beta-prop_TEP1_C 14 liisAseDrtvKlWdretkkqvGlFvCea 42 +s+s+D+tvK+Wd + + v F+ ++ FUN_001898-T1 245 HFVSSSSDKTVKVWDAGSRQCVQTFYQHS 273 579*******************9998665 PP >> Beta-prop_WDR75_1st WD repeat-containing protein 75 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.1 0.0006 0.23 13 74 .. 39 101 .. 27 107 .. 0.80 2 ! 9.0 0.0 0.0028 1.1 188 252 .. 110 171 .. 104 180 .. 0.86 3 ! 15.4 0.0 3.2e-05 0.012 3 65 .. 156 218 .. 153 220 .. 0.90 4 ! 29.6 0.3 1.5e-09 5.8e-07 2 74 .. 197 269 .. 195 271 .. 0.89 5 ? 3.8 0.0 0.11 43 25 62 .. 263 299 .. 260 302 .. 0.81 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0006 Beta-prop_WDR75_1st 13 sGdsvkvyststeecvh...elkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktf 74 d+vk + te+ +h +++gh+ v v +n + l s+sld+ +r+wd g +k++ FUN_001898-T1 39 VDDMVKCWR-WTEDKLHlrfNFEGHQLGVVSVDVNLTGTLAA-SSSLDSHIRIWDLESGKQLKAI 101 567777775.4666666334689**************99975.89***********999888875 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0028 Beta-prop_WDR75_1st 188 cvachpkddciatGhedGkirlwrnfnqkkeytystlhwhhdavsslvftpeGtnllsGGvesvl 252 +va p+ iatG + Gki l + kke + t + +s++++p+G + G ++ ++ FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVESGKKESALDT---RGKFTMSIAYSPDGHYIACGAIDGII 171 588999*************************76666...567789999******99999998876 PP == domain 3 score: 15.4 bits; conditional E-value: 3.2e-05 Beta-prop_WDR75_1st 3 skdsrfllcasGd.svkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdf 65 s d++++ c + d +++++ +t + +h+l+gh+ + +++ p +l + ++s d ++++d FUN_001898-T1 156 SPDGHYIACGAIDgIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLI-TASDDNHIKIYDV 218 67999****88764789******************************965.7899******996 PP == domain 4 score: 29.6 bits; conditional E-value: 1.5e-09 Beta-prop_WDR75_1st 2 iskdsrfllcasGd.svkvyststeecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrlwdftdgiliktf 74 +s ds++l+ as d +k+y + + +l gh v Gv + p n v s+s d tv++wd ++tf FUN_001898-T1 197 FSPDSQLLITASDDnHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFV-SSSSDKTVKVWDAGSRQCVQTF 269 789*********8736*******************************8655.8889********8777777776 PP == domain 5 score: 3.8 bits; conditional E-value: 0.11 Beta-prop_WDR75_1st 25 eecvhelkghtdlvtGvalnpsnhlqvyscsldgtvrl 62 +cv+++ h+d+v Gv+ n + ++ s s d +v + FUN_001898-T1 263 RQCVQTFYQHSDQVWGVKYNATGS-KIVSVSDDKSVIV 299 68****************998764.6778888887765 PP >> WD40_MABP1-WDR62_1st MABP1/WDR62 first WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.0014 0.52 59 101 .. 82 124 .. 25 143 .. 0.78 2 ! 32.2 0.0 2.4e-10 9.4e-08 25 143 .. 134 249 .. 122 253 .. 0.86 3 ! 8.3 0.7 0.0044 1.7 62 108 .. 253 299 .. 248 302 .. 0.88 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0014 WD40_MABP1-WDR62_1st 59 ghlpavrvwdvaeksqvaelqkhkygvacvafspnekyivsvg 101 + +r+wd++ +q+ +++ vafsp++++i + FUN_001898-T1 82 SLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGS 124 4556799***************999999*********997643 PP == domain 2 score: 32.2 bits; conditional E-value: 2.4e-10 WD40_MABP1-WDR62_1st 25 pkknkqkhilntsrkalsalafspdGkylvtGesghlpavrvwdvaeksqvaelqkhkygvacvafspnekyivsvgyqhdmvvnvwdw 113 + k++ l+t k ++a+spdG+y+ +G + ++d++ + + +l++h + ++fsp+++ +++ d ++++d FUN_001898-T1 134 VESGKKESALDTRGKFTMSIAYSPDGHYIACGAID--GIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITA--SDDNHIKIYDV 218 556677888999999999************99765..799*******************************99876..7788999***9 PP WD40_MABP1-WDR62_1st 114 kkdvvvaa.nkvsskvtavsfsedssyfvtv 143 + + + s v +vsf d+++fv+ FUN_001898-T1 219 QHANLAGTlSGHGSWVLGVSFCPDNTHFVSS 249 998887652567899**************75 PP == domain 3 score: 8.3 bits; conditional E-value: 0.0044 WD40_MABP1-WDR62_1st 62 pavrvwdvaeksqvaelqkhkygvacvafspnekyivsvgyqhdmvv 108 +v+vwd ++ v ++ +h v v++ + + ivsv ++ ++v FUN_001898-T1 253 KTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIV 299 689************************************87766655 PP >> Beta-prop_ACSF4 Beta-alanine-activating enzyme, beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.073 28 227 300 .. 31 102 .. 17 108 .. 0.72 2 ! 47.5 0.1 5.5e-15 2.1e-12 15 164 .. 112 261 .. 98 273 .. 0.88 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.073 Beta-prop_ACSF4 227 eekivfgshdgllyclsv.sgellwkveldseifatPfvfeesegsnekllavastdGklflldletgevlaslk 300 +e+iv+g+ d ++ c + + +l+ +++++ + + +v + + +l+a +s d ++ ++dle+g+ l+ ++ FUN_001898-T1 31 TENIVTGAVDDMVKCWRWtEDKLHLRFNFEGHQLGVVSVDVNLT---GTLAASSSLDSHIRIWDLESGKQLKAID 102 46788888888888888525788888888777776666665433...4577788888888888888887766655 PP == domain 2 score: 47.5 bits; conditional E-value: 5.5e-15 Beta-prop_ACSF4 15 tvdksselvvvgSHsgkivcvdletgeviweielpdriEssacvskdgklvvvGcydgklycldlatgeilwkfktgd.aiKsspvidsesglv 107 +++ +s++++ gSH+gki + +e+g+ + ++ +++ s+++s+dg ++ G dg + ++dl+tg++l + + i+s + ++s+l+ FUN_001898-T1 112 AFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAmPIRSLT-FSPDSQLL 204 45567899*******************************************************************6551688775.568899** PP Beta-prop_ACSF4 108 vvgsydknlyaldvesgklvwklklggsifsspllskskesvlvatldGtvaalsee 164 + +s d+++ +dv+ +l +l+ +gs++ ++ ++++ + + d+tv ++ FUN_001898-T1 205 ITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAG 261 *************************************99999999999999877655 PP >> Beta-prop_IFT122_1st IFT122 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.0 0.7 6.2e-05 0.024 22 158 .. 29 174 .. 6 183 .. 0.72 2 ! 35.9 1.0 1.4e-11 5.5e-09 14 112 .. 192 293 .. 185 300 .. 0.87 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 6.2e-05 Beta-prop_IFT122_1st 22 dgtqlilaagsrllv..y.dtsdgt.llqplkghkdtvycvayakdgkrfasgsadksviiwtsklegilkythndaiq..cvsynpit 104 dgt+ i++ +v + t d l ++gh+ v v g as s d + iw + lk ++ v++ p + FUN_001898-T1 29 DGTENIVTGAVDDMVkcWrWTEDKLhLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPVDtwTVAFSPDS 117 66666555444333311212445441345789******************************9999999999988777633699***** PP Beta-prop_IFT122_1st 105 hqlascsss.dfglwspeq.ksvskhksssk.iiccswtndgqylalgmfngiisir 158 + +a+ s + + l e k s + k + +++ dg+y+a g ++gii+i FUN_001898-T1 118 RFIATGSHAgKINLIGVESgKKESALDTRGKfTMSIAYSPDGHYIACGAIDGIINIF 174 **99988652556655543234444444444157889*****************996 PP == domain 2 score: 35.9 bits; conditional E-value: 1.4e-11 Beta-prop_IFT122_1st 14 indiafkpdgtqlilaag.srllvydtsdgtllqplkghkdtvycvayakdgkrfasgsadksviiwtsklegilk..ythndaiqcvs 99 i ++f pd li a+ +++ +yd l l gh v v+++ d +f s s+dk+v +w + ++ y h d + v FUN_001898-T1 192 IRSLTFSPDSQLLITASDdNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQtfYQHSDQVWGVK 280 77899****99999988625788********************************************876655543349********** PP Beta-prop_IFT122_1st 100 ynpithqlascss 112 yn ++ s+s FUN_001898-T1 281 YNATGSKIVSVSD 293 ****999999885 PP >> Beta-prop_EML Echinoderm microtubule-associated protein first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.8 1.3e-11 5.1e-09 39 230 .. 39 221 .. 13 228 .. 0.78 2 ! 16.2 0.5 2.1e-05 0.0081 40 126 .. 210 289 .. 207 300 .. 0.85 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 1.3e-11 Beta-prop_EML 39 akphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllvtcGkkhia 134 + +++ W+ + + ++ + ++ gv++++ + +L a +s ++ + +Wd ++g++l + + v+f+p + ++ G + FUN_001898-T1 39 VDDMVKCWRWTEDKLHLRFNFEGHQLGVVSVDVNLTG---TL-AASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPD--SRFIATGSH-AG 127 4668888888887777777778899******999643...44.456677788*****************************6..567888864.44 PP Beta-prop_EML 135 FWtlegkklekkkgifeksekpkyvlclafsengdvi.tGdsnGnilvWskgtnkiskavkkahegsvfsllvlkdgtllsgggkdgkivawdanl 229 +l g + kk+ +++ + k+ +++a+s++g+ i G +G i +++ +t k+ ++++ h ++ sl++++d++ll + d++i+ +d + FUN_001898-T1 128 KINLIGVESGKKESALDT--RGKFTMSIAYSPDGHYIaCGAIDGIINIFDLTTGKLLHTLE-GHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQH 220 455666666667777765..578************6637999***********9**99988.9*******************9***9999888665 PP Beta-prop_EML 230 e 230 FUN_001898-T1 221 A 221 4 PP == domain 2 score: 16.2 bits; conditional E-value: 2.1e-05 Beta-prop_EML 40 kphiriWdsetletlavlgkgefergvsclaFskadggklLaavdesnehvlsvWdwqkgeklaetktskdkvlavefhpldknllv 126 + hi+i d++ + l+ + + v+ ++F+ ++ v +s+++++ vWd +++ +++ ++d+v +v+++ + ++ +v FUN_001898-T1 210 DNHIKIYDVQHANLAGTLS--GHGSWVLGVSFCPDN----THFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSK-IV 289 6799999999998888874..38899*******866....3578899999****************************998765.44 PP >> Beta-prop_Aladin Aladin seven-bladed propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.2 0.0 0.00027 0.1 112 210 .. 65 163 .. 31 184 .. 0.79 2 ! 29.6 0.3 1.3e-09 5.1e-07 109 219 .. 188 298 .. 167 303 .. 0.87 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00027 Beta-prop_Aladin 112 pvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvwetetWtcerWtvlkgrvq.aacws 203 v+sv + +G+ L+++s d+ i +Wd + + g + +++spd + + +++ + +e+ + e ++g+ + ++s FUN_001898-T1 65 GVVSVDVNLTGT-LAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTmSIAYS 156 688888888886.6667789********99998888888888889999*****9999888888888888999999999988888865277999 PP Beta-prop_Aladin 204 pdgsvll 210 pdg+ + FUN_001898-T1 157 PDGHYIA 163 9998765 PP == domain 2 score: 29.6 bits; conditional E-value: 1.3e-09 Beta-prop_Aladin 109 ghspvtsvaWspkGdlLvsaspvdtsilvWdvaketavpLrrvggggvsllkwspdgskllaatpssvfrvwetetWtc.erWtvlkgrvqaa 200 + +p+ s+++sp+ +lL++as d+ i ++dv++ + g+ v +++ pd+++ +++++ + +vw++ + +c + + + + +v FUN_001898-T1 188 HAMPIRSLTFSPDSQLLITASD-DNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCvQTFYQHSDQVWGV 279 347****************995.999********9999888888999999************************8888736688899999999 PP Beta-prop_Aladin 201 cwspdgsvllfateeepvi 219 + + gs ++ ++++++vi FUN_001898-T1 280 KYNATGSKIVSVSDDKSVI 298 9999999999998888776 PP >> WDR90_beta-prop_4th WDR90, 4th beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.48 1.8e+02 40 115 .. 14 89 .. 8 102 .. 0.63 2 ! 21.9 0.0 2.8e-07 0.00011 12 131 .. 76 189 .. 65 195 .. 0.83 3 ! 16.2 0.9 1.5e-05 0.006 4 115 .. 194 299 .. 191 303 .. 0.83 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.48 WDR90_beta-prop_4th 40 lnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelk..lhphavaltaiaysadGqtilsgdkdGlvav 115 ++s +aw s +++v+G d ++ ++ + ++ l+ + h+ ++++ G + s+ d + + FUN_001898-T1 14 HEDSIWTVAWGTSDKD--GTENIVTGAVDDMVKCWRWTEDKLHLRfnFEGHQLGVVSVDVNLTGTLAASSSLDSHIRI 89 5566667777655444..566778888888888888777666665114577777777777777777766666655554 PP == domain 2 score: 21.9 bits; conditional E-value: 2.8e-07 WDR90_beta-prop_4th 12 shlatcsedGsvrvwslasmelvvqfqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelklhphavaltaiaysadG 101 + a+ s d +r+w l+s + + ++ +a+s ++++ +++G G + ++ + + + e l ++iays dG FUN_001898-T1 76 TLAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAFS------PDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDG 159 5678889999*******9988554444443344444444......57778**************************************** PP WDR90_beta-prop_4th 102 qtilsgdkdGlvavssprtGvtlrvlsdhk 131 + i g dG++ + +tG l l+ h FUN_001898-T1 160 HYIACGAIDGIINIFDLTTGKLLHTLEGHA 189 **********************99999884 PP == domain 3 score: 16.2 bits; conditional E-value: 1.5e-05 WDR90_beta-prop_4th 4 evvfspdeshlatcsedGsvrvwslasmelvvqfqvlnqsclclawspsssaraeqqqvvaGysdGtlrvfsisrtemelklhphavalt 93 ++fspd++ l t s+d ++++ ++ +l + +w s +++ + v+ sd t++v+ + + ++ h+ + FUN_001898-T1 194 SLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGH------GSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVW 277 679********************99999987654433......356666667788899999***********999999999********* PP WDR90_beta-prop_4th 94 aiaysadGqtilsgdkdGlvav 115 ++y a G i+s d v v FUN_001898-T1 278 GVKYNATGSKIVSVSDDKSVIV 299 **********999776665544 PP >> Beta-prop_RIG_2nd RIG second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.6 0.15 59 210 249 .. 11 53 .. 5 63 .. 0.79 2 ? 5.1 0.0 0.048 19 229 251 .. 77 99 .. 50 109 .. 0.74 3 ! 8.0 0.0 0.006 2.3 14 76 .. 85 144 .. 83 150 .. 0.74 4 ! 12.1 0.0 0.00033 0.13 41 75 .. 151 185 .. 145 192 .. 0.89 5 ! 10.3 0.0 0.0013 0.49 210 276 .. 185 250 .. 180 252 .. 0.88 6 ? 6.1 0.1 0.023 8.9 220 263 .. 237 279 .. 226 293 .. 0.76 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.15 Beta-prop_RIG_2nd 210 asaekasitsvkwsnan...snlllsfsidgkvkvWdleepek 249 +a+++si +v+w ++ + +++ +d+ vk W e++ FUN_001898-T1 11 DQAHEDSIWTVAWGTSDkdgTENIVTGAVDDMVKCWRWTEDKL 53 57899********76652246899************9888764 PP == domain 2 score: 5.1 bits; conditional E-value: 0.048 Beta-prop_RIG_2nd 229 lllsfsidgkvkvWdleepekee 251 l s+s+d+++++Wdle++++ + FUN_001898-T1 77 LAASSSLDSHIRIWDLESGKQLK 99 556889************99843 PP == domain 3 score: 8.0 bits; conditional E-value: 0.006 Beta-prop_RIG_2nd 14 rrvalldlsklsakklsieslkvkskvlsLaWspdkenLAfgTaeGrvGildvekmkvktllr 76 ++++dl + ++ i++ v++ ++a spd++ +A g G++ ++ ve+ k++++l FUN_001898-T1 85 SHIRIWDLES-GKQLKAIDCGPVDT--WTVAFSPDSRFIATGSHAGKINLIGVESGKKESALD 144 5566666644.33444566666654..578999999999999999999999999999998876 PP == domain 4 score: 12.1 bits; conditional E-value: 0.00033 Beta-prop_RIG_2nd 41 lsLaWspdkenLAfgTaeGrvGildvekmkvktll 75 +s+a+spd + +A+g +G + i+d ++ k ++l FUN_001898-T1 151 MSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTL 185 79***********************9998876665 PP == domain 5 score: 10.3 bits; conditional E-value: 0.0013 Beta-prop_RIG_2nd 210 asaekasitsvkwsnansnlllsfsidgkvkvWdleepekeeltitykcpmlcglFlPtdenivlcg 276 + + i s+++s+ s+ll++ s d+++k++d+++ + + ++ + + +l F P + ++v ++ FUN_001898-T1 185 LEGHAMPIRSLTFSPD-SQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSS 250 567888999*****95.799********************999999999999999*****9999766 PP == domain 6 score: 6.1 bits; conditional E-value: 0.023 Beta-prop_RIG_2nd 220 vkwsnansnlllsfsidgkvkvWdleepekeeltitykcpmlcg 263 v++ + n + ++s+s d +vkvWd + + ++ ++++ ++ FUN_001898-T1 237 VSFCPDNTH-FVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGV 279 666666666.567799*********9999999899988888865 PP >> Beta-prop_WDR19_1st WDR19 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 0.0 6.3e-10 2.4e-07 10 152 .. 75 219 .. 73 230 .. 0.85 2 ? -0.1 0.1 1.4 5.4e+02 253 281 .. 267 295 .. 255 302 .. 0.72 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 6.3e-10 Beta-prop_WDR19_1st 10 gnylavagknkvvkiyd.rqGelvdeikl.kgkctaleWdkdgdlLaiiqeksslvllwdant.kktskldtglkdkltfllWskkspiL 96 g++ a + ++ ++i+d +G++++ i+ + + +++ + d ++a ++ ++ l +++ kk s ldt+ k + ++ s +++++ FUN_001898-T1 75 GTLAASSSLDSHIRIWDlESGKQLKAIDCgPVDTWTVAFSPDSRFIATGSHAG-KINLIGVESgKKESALDTRGKFT-MSIAYSPDGHYI 162 667788889999****95579******995678999***********999865.566666665277789***99964.6789******** PP Beta-prop_WDR19_1st 97 avGtskGnlllYnkktskkipilGkHskkItcgaws.kenlLalgseDktltisnae 152 a G G + +++ +t k + +l H+ I + ++s +++lL+++s+D+ + i +++ FUN_001898-T1 163 ACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSpDSQLLITASDDNHIKIYDVQ 219 ***********************************955678999*******999876 PP == domain 2 score: -0.1 bits; conditional E-value: 1.4 Beta-prop_WDR19_1st 253 fqvknhkdslsdialseslkkvascgdnt 281 + +h+d++ ++++ + +k++s++d++ FUN_001898-T1 267 QTFYQHSDQVWGVKYNATGSKIVSVSDDK 295 45567888888888888888888887764 PP >> Beta-prop_WDR35_TULP_N WDR35/TULP4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.1 0.067 26 147 182 .. 96 131 .. 11 148 .. 0.67 2 ! 15.4 0.0 2.9e-05 0.011 59 195 .. 51 187 .. 40 192 .. 0.87 3 ! 15.1 0.0 3.5e-05 0.013 118 187 .. 150 220 .. 143 225 .. 0.89 4 ! 11.4 0.4 0.00047 0.18 65 141 .. 225 299 .. 220 302 .. 0.91 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.067 Beta-prop_WDR35_TULP_N 147 nrlwgkelkklklakvewspdgklllfglkegevhv 182 ++l + + ++ +v++spd++++ g++ g++++ FUN_001898-T1 96 KQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKINL 131 344444444444555666666666666666666654 PP == domain 2 score: 15.4 bits; conditional E-value: 2.9e-05 Beta-prop_WDR35_TULP_N 59 snlsmnqtlegHsgavqvvaWNekykkLtssDenGliivWmlykgswveeminnrnksvvkdlkWssdgqkicivyedGav.ivGsv 144 +l++ + egH+ v v N + + +ss + i +W l++g+ ++ i+ ++ s+d + i+ + G++ ++G FUN_001898-T1 51 DKLHLRFNFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKA-IDCGP-VDTWTVAFSPDSRFIATGSHAGKInLIGVE 135 567778889***************999999***************98876.44443.44567899***************9789999 PP Beta-prop_WDR35_TULP_N 145 dGnrlwgkelkklklakvewspdgklllfglkegevhvyd.segnflsklkl 195 G++ + + +++ +++++spdg+++ g +g ++++d ++g+ l++l+ FUN_001898-T1 136 SGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDlTTGKLLHTLEG 187 9**********999999***********************667999988875 PP == domain 3 score: 15.1 bits; conditional E-value: 3.5e-05 Beta-prop_WDR35_TULP_N 118 vkdlkWssdgqkicivyedGav.ivGsvdGnrlwgkelkklklakvewspdgklllfglkegevhvydseg 187 +++++s+dg+ i+ dG + i G+ l + e + + + ++++spd++ll+ ++ + ++++yd + FUN_001898-T1 150 TMSIAYSPDGHYIACGAIDGIInIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQH 220 5678999*************996778889***************************************765 PP == domain 4 score: 11.4 bits; conditional E-value: 0.00047 Beta-prop_WDR35_TULP_N 65 qtlegHsgavqvvaWNekykkLtssDenGliivWmlykgswveeminnrnksvvkdlkWssdgqkicivyedGaviv 141 tl+gH + v v++ ++++ ss ++ ++ vW + + + v+ + + ++ +v ++k++++g+ki+ v +d +viv FUN_001898-T1 225 GTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQ--HSDQVWGVKYNATGSKIVSVSDDKSVIV 299 699*********************************99999998865..56789**********************9 PP >> Tricorn_2nd Tricorn protease second beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.0 1.6e-06 0.00063 69 141 .. 90 163 .. 76 180 .. 0.80 2 ! 21.6 0.0 2.7e-07 0.0001 45 159 .. 111 219 .. 109 228 .. 0.73 3 ? 6.4 0.0 0.011 4.4 85 137 .. 191 243 .. 168 277 .. 0.62 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 1.6e-06 Tricorn_2nd 69 ldadgseka.ltdedlgrieelkvspdgkkiavannrneLllvdletgeatlidkseegaiedfswspdsrwlA 141 d ++ ++ +d + + +++ spd+++ia + + ++ l+ +e+g+++ + + ++++spd++++A FUN_001898-T1 90 WDLESGKQLkAIDCGPVDTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIA 163 444544443356666666678999**********************9988888778888899***********9 PP == domain 2 score: 21.6 bits; conditional E-value: 2.7e-07 Tricorn_2nd 45 vewlndgkrvaavsdeeeeeelvildadgseka.ltdedlgrieelkvspdgkkiavannrneLllvdletgeatlidkseegaiedfswspdsrw 139 v++++d + +a+ s ++ + + ++ +k+ d + +++ spdg +ia + + + dl+tg+ + + i+++++spds++ FUN_001898-T1 111 VAFSPDSRFIATGSH---AGKINLIGVESGKKEsALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQL 203 566777773333333...444444444444444357777778889999999999999999999999999999999999999999999999999999 PP Tricorn_2nd 140 lAYsfpesnettsIklydve 159 l ++++ + Ik+ydv+ FUN_001898-T1 204 LITASDD----NHIKIYDVQ 219 9755544....568888876 PP == domain 3 score: 6.4 bits; conditional E-value: 0.011 Tricorn_2nd 85 rieelkvspdgkkiavannrneLllvdletgeatlidkseegaiedfswspds 137 i++l spd++ ++ a + n + ++d+++ + + + + + ++s+ pd+ FUN_001898-T1 191 PIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDN 243 35555566666666666666666666666555555555555555555555555 PP >> Beta-prop_WDR41 WDR41 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0052 2 104 128 .. 77 101 .. 32 124 .. 0.81 2 ! 17.8 0.0 3.9e-06 0.0015 55 123 .. 161 222 .. 148 238 .. 0.84 3 ! 14.8 0.4 3.2e-05 0.013 56 128 .. 204 269 .. 198 282 .. 0.79 4 ! 9.3 0.5 0.0016 0.6 52 119 .. 242 302 .. 225 303 .. 0.77 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0052 Beta-prop_WDR41 104 liltassdktvivwdiesgrqlkki 128 l ++s d + +wd+esg+qlk i FUN_001898-T1 77 LAASSSLDSHIRIWDLESGKQLKAI 101 444567799999**********987 PP == domain 2 score: 17.8 bits; conditional E-value: 3.9e-06 Beta-prop_WDR41 55 rfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdiesgr 123 +a + dgi+ ++d+ tg+ l l gh+ i +++ + s+l++tas d+ + ++d++ + FUN_001898-T1 161 YIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTF-------SPDSQLLITASDDNHIKIYDVQHAN 222 4566778**********************99988764.......46789***************98765 PP == domain 3 score: 14.8 bits; conditional E-value: 3.2e-05 Beta-prop_WDR41 56 fasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdiesgrqlkki 128 +++a+dd + ++dvq + l gh + + + +++ +++ssdktv vwd s + ++ FUN_001898-T1 204 LITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCP-DNT------HFVSSSSDKTVKVWDAGSRQCVQTF 269 689************************99887765433.332......36799***********998888765 PP == domain 4 score: 9.3 bits; conditional E-value: 0.0016 Beta-prop_WDR41 52 ddfrfasagddgivflwdvqtgeillelhghtqkitaivvfkaekiseeksdliltassdktvivwdi 119 d+ f+s++ d +v +wd + + + ++ h +++ + + + + i++ s dk+viv+++ FUN_001898-T1 242 DNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKY-------NATGSKIVSVSDDKSVIVYNC 302 7788999999999999999999999999999998876532.......233445778888888888887 PP >> Beta-prop_VPS8 Vps8 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.015 5.7 66 104 .. 63 101 .. 49 107 .. 0.85 2 ? 3.1 0.0 0.13 52 64 99 .. 101 138 .. 99 153 .. 0.83 3 ! 23.4 0.3 9.4e-08 3.6e-05 33 136 .. 160 258 .. 146 272 .. 0.86 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.015 Beta-prop_VPS8 66 qgaVsalafnadstrllaGyarGqilmwDlsngkllrti 104 q V ++++n ++t + + +i++wDl++gk l+ i FUN_001898-T1 63 QLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAI 101 4567789***************************99987 PP == domain 2 score: 3.1 bits; conditional E-value: 0.13 Beta-prop_VPS8 64 aeqgaVs..alafnadstrllaGyarGqilmwDlsngk 99 ++g+V +af+ ds +++G G+i ++ +++gk FUN_001898-T1 101 IDCGPVDtwTVAFSPDSRFIATGSHAGKINLIGVESGK 138 56777752359************************997 PP == domain 3 score: 23.4 bits; conditional E-value: 9.4e-08 Beta-prop_VPS8 33 sliavGTshGlvLvFdse.qtLklclgstakgaeqgaVsalafnadstrllaGyarGqilmwDlsngkllrtisdahppgtavlhikFtddptla 126 ++ia G G++ +Fd + +L ++l+ +a ++ +l+f+ ds+ l++ + +i ++D+++++l t+s +g+ vl ++F+ d+t + FUN_001898-T1 160 HYIACGAIDGIINIFDLTtGKLLHTLEGHA-----MPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSG---HGSWVLGVSFCPDNTHF 246 79**************99889998888765.....5********************************9999874...6899*********9999 PP Beta-prop_VPS8 127 lvs..DsgGsvF 136 + s D+ v+ FUN_001898-T1 247 VSSssDKTVKVW 258 887445555555 PP >> Beta-prop_Nup120_160 Nucleoporin Nup120/160, beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.0 7.1e-05 0.027 185 254 .. 74 157 .. 56 160 .. 0.69 2 ! 9.8 0.0 0.001 0.39 166 255 .. 139 230 .. 108 233 .. 0.76 3 ! 9.8 0.2 0.001 0.4 181 211 .. 238 268 .. 229 303 .. 0.73 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 7.1e-05 Beta-prop_Nup120_160 185 ddtllftvclDhkLRvWslktgkcvatidll......eerdpqesrkkltldpsqsnllkvv........gsdgglylvvtysp 254 ++tl+ + +lD ++R+W+l++gk + +id+ ++p+++ + + + nl+ v +++g+ ++ + ysp FUN_001898-T1 74 TGTLAASSSLDSHIRIWDLESGKQLKAIDCGpvdtwtVAFSPDSRFIATGSHAGKINLIGVEsgkkesalDTRGKFTMSIAYSP 157 678888889********************9977666655666665555555555555555546666666555555666666666 PP == domain 2 score: 9.8 bits; conditional E-value: 0.001 Beta-prop_Nup120_160 166 ggrseelsastavavveseddtllftvclDhkLRvWslktgkcvatidll......eerdpqesrkkltldpsqsnllkvvgsdgglyl 248 +++ ++ + +++++ s+d+ ++ + +D+ + +++l+tgk+++t + + +++l + s+ n +k++ + ++ l FUN_001898-T1 139 KESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHampirsL---TFSPDSQLLITASDDNHIKIY-DVQHANL 223 3444467777888999999**************************944444455432...344466778999999999999.8888888 PP Beta-prop_Nup120_160 249 vvtyspp 255 + t+s + FUN_001898-T1 224 AGTLSGH 230 8888765 PP == domain 3 score: 9.8 bits; conditional E-value: 0.001 Beta-prop_Nup120_160 181 veseddtllftvclDhkLRvWslktgkcvat 211 + +d+t+ ++ + D++++vW+ +++cv t FUN_001898-T1 238 SFCPDNTHFVSSSSDKTVKVWDAGSRQCVQT 268 33479************************98 PP >> Beta-prop_SPT8 SPT8 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.011 4.2 124 192 .. 44 113 .. 33 130 .. 0.80 2 ! 15.1 0.0 2.8e-05 0.011 300 375 .. 149 222 .. 116 232 .. 0.84 3 ! 9.9 0.1 0.0011 0.42 141 203 .. 230 293 .. 219 301 .. 0.78 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.011 Beta-prop_SPT8 124 qgvrydeGriahylk.akhsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgatselsalel 192 + r++e ++ + ++h+ v + +n t + s+s d +i wdl+ gk+ + + + ++++ FUN_001898-T1 44 KCWRWTEDKLHLRFNfEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAIDCGPVDTWTVAF 113 5668888888888875579888888899999999*******************99988776666655555 PP == domain 2 score: 15.1 bits; conditional E-value: 2.8e-05 Beta-prop_SPT8 300 wclsacwsadGdyiyaGrrnacveefdlkmpskpkstlklpsisGpvsavkslpnekhlliaskdn.irlydlekss 375 + +s +s dG+yi G ++ ++ fdl k +tl + p+ ++ p+ + l+ as dn i++yd+++++ FUN_001898-T1 149 FTMSIAYSPDGHYIACGAIDGIINIFDLTT-GKLLHTL--EGHAMPIRSLTFSPDSQLLITASDDNhIKIYDVQHAN 222 67999**********************985.4556665..4566788888888************989****99876 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0011 Beta-prop_SPT8 141 hsnvvnilrlnstedkflsgswdkkilewdlntgkvineykgatselsalelrplfst.vtles 203 h + v + + +++ f+s+s dk + wd + ++ + +++ ++ +++ s v++++ FUN_001898-T1 230 HGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKiVSVSD 293 666666667778899********************************99999877654134444 PP >> Beta-prop_NWD2_C NWD2 C-terminal beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.34 1.3e+02 7 47 .. 62 103 .. 56 112 .. 0.69 2 ? 3.5 0.0 0.11 44 317 338 .. 152 173 .. 111 176 .. 0.86 3 ! 24.1 0.0 6.6e-08 2.5e-05 2 113 .. 183 296 .. 182 303 .. 0.85 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.34 Beta-prop_NWD2_C 7 lelqidsislaeeaelavtvt.RncvgvWdletgkLlkklad 47 ++l + s+++ + +la++ + +++ +Wdle+gk lk + FUN_001898-T1 62 HQLGVVSVDVNLTGTLAASSSlDSHIRIWDLESGKQLKAIDC 103 556666666666666766655256899999999998887655 PP == domain 2 score: 3.5 bits; conditional E-value: 0.11 Beta-prop_NWD2_C 317 aiestedgksivlgtvDGsltv 338 +i+ + dg+ i++g++DG + + FUN_001898-T1 152 SIAYSPDGHYIACGAIDGIINI 173 688899************9876 PP == domain 3 score: 24.1 bits; conditional E-value: 6.6e-08 Beta-prop_NWD2_C 2 hvidrlelqidsislaeeaelavtvt.RncvgvWdletgkLlkkladsslgaivthavitkdgkyvvsaesgkvl.iwelekeqvlfke..eq 90 h+++ + ++i s++++ +++l +t++ n++ ++d++++ L +l+ +g+ v d ++ vs+ s+k + +w++ ++q +++ + FUN_001898-T1 183 HTLEGHAMPIRSLTFSPDSQLLITASdDNHIKIYDVQHANLAGTLSG--HGSWVLGVSFCPDNTHFVSSSSDKTVkVWDAGSRQCVQTFyqHS 273 89999*******************983589***************98..8888888888888888888777765549***9999887651166 PP Beta-prop_NWD2_C 91 kdvkqlllleddtkviavskeke 113 +v + + ++k+++vs +k+ FUN_001898-T1 274 DQVWGVKYNATGSKIVSVSDDKS 296 78999**************9876 PP >> Beta-prop_Vps41 Vps42 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.0 0.019 7.5 50 89 .. 58 97 .. 49 104 .. 0.86 2 ! 21.7 0.1 3.9e-07 0.00015 26 101 .. 117 195 .. 104 202 .. 0.78 3 ! 8.5 0.0 0.0039 1.5 36 87 .. 169 221 .. 169 235 .. 0.90 4 ? 7.1 0.3 0.011 4.1 26 118 .. 201 291 .. 191 302 .. 0.78 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.019 Beta-prop_Vps41 50 tfkahrasisslsidtdGeylAsaSmDGtvvigslseeee 89 +f+ h+ + s+ ++ G+ As+S+D ++ i l++ ++ FUN_001898-T1 58 NFEGHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQ 97 67889999999999******************99988776 PP == domain 2 score: 21.7 bits; conditional E-value: 3.9e-07 Beta-prop_Vps41 26 ekvlvfgthsGiihildpdg.ntirtfkahrasisslsidtdGeylAsaSmDGtvvigslseeeeiav..dFkrpvkav 101 +++++ g+h G+i ++ ++ ++ + ++ + + ++s+ + dG+y+A++++DG + i+ l++ + ++ +p+++ FUN_001898-T1 117 SRFIATGSHAGKINLIGVESgKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTleGHAMPIRSL 195 68999***********88762666677777777889999*******************999988654321466666655 PP == domain 3 score: 8.5 bits; conditional E-value: 0.0039 Beta-prop_Vps41 36 Giihildpdg.ntirtfkahrasisslsidtdGeylAsaSmDGtvvigslsee 87 Gii i+d ++ + ++t++ h++ i sl+ + d++ l +aS+D ++ i+ ++++ FUN_001898-T1 169 GIINIFDLTTgKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHA 221 89999997653899*********************************988765 PP == domain 4 score: 7.1 bits; conditional E-value: 0.011 Beta-prop_Vps41 26 ekvlvfgthsGiihildpdg.ntirtfkahrasisslsidtdGeylAsaSmDGtvvigslseeeeiavdFkrpvkavaldpnysksssksfisG 118 +++l+ +++ i i+d++ n t++ h + + +s d +++ s+S D tv + +++ ++ ++ ++ ++ n + +++s FUN_001898-T1 201 SQLLITASDDNHIKIYDVQHaNLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATG---SKIVSV 291 678999999999****9998467789999999999********************999998888888888888777777766643...344444 PP >> WD40_RFWD3 E3 ubiquitin-protein ligase RFWD3 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.1 4 1.6e+03 104 126 .. 15 40 .. 7 71 .. 0.67 2 ? 6.9 0.0 0.012 4.7 280 317 .. 76 111 .. 65 127 .. 0.70 3 ? 2.0 0.1 0.38 1.5e+02 116 142 .. 158 183 .. 152 188 .. 0.77 4 ! 15.4 0.0 3.1e-05 0.012 61 95 .. 188 221 .. 180 228 .. 0.90 5 ! 10.4 0.4 0.0011 0.41 65 115 .. 234 284 .. 227 301 .. 0.78 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 4 WD40_RFWD3 104 dspvWsCcWsedds...nylyaGlqn 126 + ++W+ +W ++d+ + + +G+ + FUN_001898-T1 15 EDSIWTVAWGTSDKdgtENIVTGAVD 40 56899999998875111345555555 PP == domain 2 score: 6.9 bits; conditional E-value: 0.012 WD40_RFWD3 280 lvaagdeasksvllWdassgkqlqklsvsspvldvcsf 317 ++aa+ + + +Wd +sgkql+ ++++ p +d ++ FUN_001898-T1 76 TLAASSSLDSHIRIWDLESGKQLKAIDCG-P-VDTWTV 111 46777778889999999999999999873.3.344444 PP == domain 3 score: 2.0 bits; conditional E-value: 0.38 WD40_RFWD3 116 dsnylyaGlqnGsvlvfDiRqtssevs 142 d y+ +G+ +G + +fD+ t + ++ FUN_001898-T1 158 DGHYIACGAIDGIINIFDLT-TGKLLH 183 678999************83.555555 PP == domain 4 score: 15.4 bits; conditional E-value: 3.1e-05 WD40_RFWD3 61 HskaiRdlaFnseqdslllsaslDktlkltsllsn 95 H+ +iR+l+F++ +ll++as D+ +k+ +++ FUN_001898-T1 188 HAMPIRSLTFSPD-SQLLITASDDNHIKIYDVQHA 221 999*********9.88***************9865 PP == domain 5 score: 10.4 bits; conditional E-value: 0.0011 WD40_RFWD3 65 iRdlaFnseqdslllsaslDktlkltsllsntvvqt.YetdspvWsCcWsed 115 + +++F + ++ +s s Dkt+k+ + s + vqt Y+ +vW ++ + FUN_001898-T1 234 VLGVSFCPD-NTHFVSSSSDKTVKVWDAGSRQCVQTfYQHSDQVWGVKYNAT 284 556788877.566778899****************95688889998776665 PP >> Beta-prop_EIPR1 EIPR1 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.4 0.39 1.5e+02 121 194 .. 27 99 .. 8 131 .. 0.65 2 ! 26.4 0.1 1.5e-08 5.8e-06 150 280 .] 139 258 .. 127 258 .. 0.78 3 ? 0.7 0.0 1 4e+02 245 277 .. 266 297 .. 261 300 .. 0.72 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.39 Beta-prop_EIPR1 121 dleGlqnevksiseealilvsldeskkgkevskyslggeelrvaAldphdsslvlvace..sglqliDlRakkkks 194 d++G++n v+ ++ + ++ +e k +++++g++l v d + ++++ s++ ++Dl + k+ + FUN_001898-T1 27 DKDGTENIVTGAVDDMVKCWRWTEDK---LHLRFNFEGHQLGVVSVDVNLTGTLAASSSldSHIRIWDLESGKQLK 99 56666666666666666666666663...35566777777777777766665555555434667777776655544 PP == domain 2 score: 26.4 bits; conditional E-value: 1.5e-08 Beta-prop_EIPR1 150 evskyslggeelrvaAldphdsslvlvacesglqliDlRakkkksvanvetlhgfgkvravdfdpakknklltagddgvvlihDiRydgsstve 243 + s ++ g+ A+ p +++ a + ++++Dl + k + + h +r++ f+p + l+ta dd ++i+D+ ++ FUN_001898-T1 139 KESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLH---TLEGH-AMPIRSLTFSPDS-QLLITASDDNHIKIYDVQ-----HAN 222 555555555555555677766666666777888899998887777...44555.566999***9975.689**************9.....778 PP Beta-prop_EIPR1 244 klkelkaheHtvkkvlfNpfydeLilscssdstlkLw 280 +l++h +v v+f p + +s+ssd+t+k w FUN_001898-T1 223 LAGTLSGHGSWVLGVSFCPDNTHF-VSSSSDKTVKVW 258 8899***************99886.699********9 PP == domain 3 score: 0.7 bits; conditional E-value: 1 Beta-prop_EIPR1 245 lkelkaheHtvkkvlfNpfydeLilscssdstl 277 ++++ h+ +v+ v++N+ + i+s s d+ + FUN_001898-T1 266 VQTFYQHSDQVWGVKYNATGSK-IVSVSDDKSV 297 5667788899999999987665.5677777665 PP >> PROPPIN PROPPIN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.072 28 170 247 .. 62 135 .. 48 144 .. 0.79 2 ! 10.4 0.0 0.00095 0.37 167 247 .. 143 219 .. 125 226 .. 0.75 3 ! 12.0 0.0 0.00031 0.12 147 196 .. 249 298 .. 228 303 .. 0.84 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.072 PROPPIN 170 hegtlaaitfnasgsklasasekgtvirvfsvpdgqklyefrrgmkryvtisslvfsmdsqflcassntetvhifkle 247 h+ + ++ +n +g+ la++s + ir++ + g++l + g ++ fs ds+f+++ s + + ++ +e FUN_001898-T1 62 HQLGVVSVDVNLTGT-LAASSSLDSHIRIWDLESGKQLKAIDCGPVD---TWTVAFSPDSRFIATGSHAGKINLIGVE 135 555566777888886.66666678899************99999755...55568*********99998888776665 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00095 PROPPIN 167 iaahegtlaaitfnasgsklasasekgtvirvfsvpdgqklyefrrgmkryvtisslvfsmdsqflcassntetvhifkle 247 + + +i++ g +a + g +i +f + g+ l+ + g + + i sl fs dsq+l ++s+ + ++i+ ++ FUN_001898-T1 143 LDTRGKFTMSIAYSPDGHYIACGAIDG-IINIFDLTTGKLLHTLE-G--HAMPIRSLTFSPDSQLLITASDDNHIKIYDVQ 219 555555556788888888888877766.78999999998877765.3..45789**********************99876 PP == domain 3 score: 12.0 bits; conditional E-value: 0.00031 PROPPIN 147 sltsgeivlydgnslktvctiaahegtlaaitfnasgsklasasekgtvi 196 s + + ++d s + v t h + + +na+gsk+ s s+ +vi FUN_001898-T1 249 SSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVI 298 4455567799**********************************999988 PP >> Cytochrom_D1 Cytochrome D1 heme domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.15 57 54 95 .. 82 124 .. 74 126 .. 0.88 2 ! 19.8 0.0 8.3e-07 0.00032 7 94 .. 119 207 .. 113 232 .. 0.86 3 ? 4.4 0.3 0.041 16 292 343 .. 252 300 .. 237 302 .. 0.86 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.15 Cytochrom_D1 54 gRDgkvtliDLwakkivaevkaG.lnarsvavSqddryvivgn 95 + D+++ + DL k ++ + G +++ va S d r++++g+ FUN_001898-T1 82 SLDSHIRIWDLESGKQLKAIDCGpVDTWTVAFSPDSRFIATGS 124 5689999999999999999999977999**********99997 PP == domain 2 score: 19.8 bits; conditional E-value: 8.3e-07 Cytochrom_D1 7 fvvverdagkvalldgdskeilarvetgyalHisrvfssdgRyvyvigRDgkvtliDLwakkivaevk.aGlnarsvavSqddryvivg 94 f + + agk++l+ +s ++ + ++t++ +s +s+dg y+ + Dg ++++DL + k +++++ + rs+ S d +++i++ FUN_001898-T1 119 FIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEgHAMPIRSLTFSPDSQLLITA 207 6778899*******************************************************999987356778999999888888765 PP == domain 3 score: 4.4 bits; conditional E-value: 0.041 Cytochrom_D1 292 ndsvaviDkktlekvltlaespglkvvhvEfnkdGdevwlSvwdgkdalvvy 343 ++ v+v+D + v+t ++++ +v v +n+ G ++ +Sv d k ++vy FUN_001898-T1 252 DKTVKVWDAGSRQCVQTFYQHSD-QVWGVKYNATGSKI-VSVSDDK-SVIVY 300 6789******************9.9**********997.7***999.88888 PP >> NBCH_WD40 Neurobeachin beta propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 3.7 1.4e+03 123 155 .. 14 50 .. 8 60 .. 0.66 2 ? 3.3 0.1 0.11 44 123 158 .. 62 97 .. 54 103 .. 0.85 3 ? -1.3 0.0 2.8 1.1e+03 129 154 .. 110 135 .. 106 147 .. 0.78 4 ! 18.9 0.0 2e-06 0.00079 263 345 .. 137 221 .. 128 226 .. 0.60 5 ? 6.4 0.2 0.013 4.8 103 153 .. 210 260 .. 207 265 .. 0.92 6 ? 6.3 0.5 0.014 5.4 115 152 .. 264 301 .. 261 303 .. 0.94 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 3.7 NBCH_WD40 123 hkdvvscvav.tsd..g.svlatGsydttvmvwevlr 155 h+d + +va tsd g + ++tG+ d v w+ ++ FUN_001898-T1 14 HEDSIWTVAWgTSDkdGtENIVTGAVDDMVKCWRWTE 50 6666666654234311324689999999999998765 PP == domain 2 score: 3.3 bits; conditional E-value: 0.11 NBCH_WD40 123 hkdvvscvavtsdgsvlatGsydttvmvwevlrars 158 h+ v +v v g++ a+ s d+ + +w++ +++ FUN_001898-T1 62 HQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQ 97 665678899*********************987765 PP == domain 3 score: -1.3 bits; conditional E-value: 2.8 NBCH_WD40 129 cvavtsdgsvlatGsydttvmvwevl 154 +va + d +++atGs+ + + v FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVE 135 57889999999999998877666555 PP == domain 4 score: 18.9 bits; conditional E-value: 2e-06 NBCH_WD40 263 GkhlassesnGrln.clelsscgeflvcaGdqGqivvrslkslevvkryeGiGkaitsltvtpeecflaGtk.dGsllvysiena 345 Gk+ ++ +++G+++ ++ s g++++c+ +G i +++l++ ++++ eG i slt +p+ +l+ + d + +y +++a FUN_001898-T1 137 GKKESALDTRGKFTmSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASdDNHIKIYDVQHA 221 5666666666665425666666667777666677777777777777777777777777776666655544430344556666554 PP == domain 5 score: 6.4 bits; conditional E-value: 0.013 NBCH_WD40 103 ensfqvislsdGrlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwev 153 +n ++ ++ +l +++ h v v+ + d + ++ s d tv vw++ FUN_001898-T1 210 DNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDA 260 7889999999999999*********************************96 PP == domain 6 score: 6.3 bits; conditional E-value: 0.014 NBCH_WD40 115 rlvqsirqhkdvvscvavtsdgsvlatGsydttvmvwe 152 + vq+ qh d v v + gs +++ s d +v+v++ FUN_001898-T1 264 QCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 579********************************996 PP >> RMC1_N Regulator of MON1-CCZ1 complex, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.017 6.7 33 76 .. 97 142 .. 76 153 .. 0.81 2 ? 0.6 0.0 2.1 8e+02 43 68 .. 151 176 .. 141 186 .. 0.76 3 ! 9.7 0.0 0.003 1.2 40 72 .. 190 222 .. 185 231 .. 0.88 4 ? 6.2 0.2 0.036 14 42 104 .. 234 293 .. 226 302 .. 0.83 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.017 RMC1_N 33 sfriedkgpvl..sikfSlDkkilavqrssksvefinfaedetsve 76 +++ d+gpv ++ fS+D++++a ++ ++++i ++++++++ FUN_001898-T1 97 QLKAIDCGPVDtwTVAFSPDSRFIATGSHAGKINLIGVESGKKESA 142 566778888873369*********************9998877655 PP == domain 2 score: 0.6 bits; conditional E-value: 2.1 RMC1_N 43 lsikfSlDkkilavqrssksvefinf 68 +si +S+D +++a + ++++++ FUN_001898-T1 151 MSIAYSPDGHYIACGAIDGIINIFDL 176 79********9997666666666555 PP == domain 3 score: 9.7 bits; conditional E-value: 0.003 RMC1_N 40 gpvlsikfSlDkkilavqrssksvefinfaede 72 p++s+ fS+D+++l +++ ++++++++++ FUN_001898-T1 190 MPIRSLTFSPDSQLLITASDDNHIKIYDVQHAN 222 58*************************998776 PP == domain 4 score: 6.2 bits; conditional E-value: 0.036 RMC1_N 42 vlsikfSlDkkilavqrssksvefinfaedetsveysqscksksakilgfvWtsn.neivlvtd 104 vl + f +D+ s+k+v++++ s ++ q++ ++s+++ g+ + + + iv v+d FUN_001898-T1 234 VLGVSFCPDNTHFVSSSSDKTVKVWDA----GSRQCVQTFYQHSDQVWGVKYNATgSKIVSVSD 293 88999*******************986....456677888888899999999987688998876 PP >> Beta-prop_HPS5 HPS5 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.1 0.53 2e+02 106 134 .. 39 70 .. 17 95 .. 0.78 2 ? 2.7 0.0 0.22 84 64 89 .. 110 135 .. 91 145 .. 0.75 3 ! 19.4 0.0 1.8e-06 0.00069 25 140 .. 113 222 .. 107 231 .. 0.86 4 ! 14.2 0.0 6.8e-05 0.026 29 90 .. 159 220 .. 144 277 .. 0.83 5 ? 2.1 0.0 0.32 1.3e+02 33 89 .. 205 261 .. 192 301 .. 0.69 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.53 Beta-prop_HPS5 106 kgskvtaLlWdesssrv...yiGdekGkvsvt 134 + v + W+e++ ++ + G++ G+vsv FUN_001898-T1 39 VDDMVKCWRWTEDKLHLrfnFEGHQLGVVSVD 70 4567999999999887766799*******984 PP == domain 2 score: 2.7 bits; conditional E-value: 0.22 Beta-prop_HPS5 64 tvaispdedlvavatsrglvvvveln 89 tva+spd ++a +++ g++ ++ ++ FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVE 135 68899999999999999998887765 PP == domain 3 score: 19.4 bits; conditional E-value: 1.8e-06 Beta-prop_HPS5 25 lavsrkflaLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelnierkqkpkrlyissehkgskvtaLlWdess 119 ++ ++f+a Gs +G+++++ e+ k l ++ +a spd +++a ++ +g + +++l+ k+l + + h+ + + +L+ + +s FUN_001898-T1 113 FSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLT-----TGKLLHTLEGHA-MPIRSLTFSPDS 201 555689***************************9999999************************7.....566777777775.689999999999 PP Beta-prop_HPS5 120 srvyiGdekGkvsvtklsssk 140 + +++ + ++++ +++ + FUN_001898-T1 202 QLLITASDDNHIKIYDVQHAN 222 999999988888888887765 PP == domain 4 score: 14.2 bits; conditional E-value: 6.8e-05 Beta-prop_HPS5 29 rkflaLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvvelni 90 +++a G+ G ++if+ ++ kll++l + +i +++spd +l+ a+++ + + +++ FUN_001898-T1 159 GHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQH 220 48******************************************************999873 PP == domain 5 score: 2.1 bits; conditional E-value: 0.32 Beta-prop_HPS5 33 aLGsstGgvyifsrealkllqlltakegaistvaispdedlvavatsrglvvvveln 89 + s + i++ ++++l +l+ + + + v+++pd+ + ++s+ v v++ FUN_001898-T1 205 ITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAG 261 445556677788888888888888888888889999988888888888888888875 PP >> Beta-prop_DCAF4 DDB1- and CUL4-associated factor 4 beta-propeller domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.014 5.2 253 312 .. 43 102 .. 28 116 .. 0.71 2 ! 10.8 0.0 0.00059 0.23 234 311 .. 152 227 .. 107 231 .. 0.80 3 ! 7.7 0.0 0.0053 2 228 273 .. 230 275 .. 225 282 .. 0.90 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.014 Beta-prop_DCAF4 253 iklwdlratkcvk..qyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllrtip 312 +k w + k ++eGh+ ++ + vn l ++ d + riw l+ ++ l++i FUN_001898-T1 43 VKCWRWTEDKLHLrfNFEGHQ--LGVVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAID 102 555555555544301566664..667788888888888888899999999999999999885 PP == domain 2 score: 10.8 bits; conditional E-value: 0.00059 Beta-prop_DCAF4 234 svqllqeeqlllaadmaGkiklwdlratkcvkqyeGhvneyaylplhvneeeGllvavGqdcytriwslkdahllrti 311 s+ + +++ + + G i+++dl + k ++ eGh l + + ll+++ d + +i+ +++a+l t+ FUN_001898-T1 152 SIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIR--SLTFSPDSQLLITASDDNHIKIYDVQHANLAGTL 227 5566667888999999*********************87655..566788999********************98876 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0053 Beta-prop_DCAF4 228 hdsavtsvqllqeeqlllaadmaGkiklwdlratkcvkqyeGhvne 273 h s v v ++ +++++ ++k+wd + +cv+ + h ++ FUN_001898-T1 230 HGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQ 275 67788889999999**************************999876 PP >> Beta-prop_SCAP SCAP Beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.2 2.3e-05 0.0088 317 381 .. 32 99 .. 24 124 .. 0.85 2 ? 4.7 0.0 0.039 15 359 395 .. 161 197 .. 147 201 .. 0.85 3 ! 13.2 2.9 0.00011 0.041 295 410 .. 179 298 .. 175 302 .. 0.75 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 2.3e-05 Beta-prop_SCAP 317 GrvvtGsqdhtvrvyrl.edsccl.ftlqGhsGgitavyidqtmvla.sGGqdGaiclwdvltGsrvs 381 +vtG+ d v+ +r ed l f ++Gh g+ +v ++ t la s d i +wd+ +G ++ FUN_001898-T1 32 ENIVTGAVDDMVKCWRWtEDKLHLrFNFEGHQLGVVSVDVNLTGTLAaSSSLDSHIRIWDLESGKQLK 99 579*************648888777*****************9988537889********99998765 PP == domain 2 score: 4.7 bits; conditional E-value: 0.039 Beta-prop_SCAP 359 vlasGGqdGaiclwdvltGsrvshvyghrGdvtslvc 395 +a G dG i ++d+ tG + + gh + sl++ FUN_001898-T1 161 YIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTF 197 6799999********9999999999999999999875 PP == domain 3 score: 13.2 bits; conditional E-value: 0.00011 Beta-prop_SCAP 295 cqltrsvqcahqkPitvlkaa..aGrvvtGsqdhtvrvyrledscclftlqGhsGgitavyi..dqtmvlasGGqdGaiclwdvltGsrvshvyg 385 +l ++++ h Pi l + + ++t s d +++y ++ + tl Gh + v d+t + s d ++ +wd + v y FUN_001898-T1 179 GKLLHTLE-GHAMPIRSLTFSpdSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFcpDNTH-FVSSSSDKTVKVWDAGSRQCVQTFYQ 271 56666665.5888888887652256799*************************998887743336665.55667899******988888****** PP Beta-prop_SCAP 386 hrGdvtslvc..ttscvissGlddlis 410 h +v + + t s ++s d + FUN_001898-T1 272 HSDQVWGVKYnaTGSKIVSVSDDKSVI 298 ****98875422777788776665555 PP >> Beta-prop_IFT140_1st IFT140 first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.2 2.1 8e+02 96 131 .. 9 48 .. 3 63 .. 0.78 2 ? 6.2 0.0 0.013 5.2 289 367 .. 77 148 .. 59 163 .. 0.68 3 ? 2.5 0.0 0.18 69 66 126 .. 111 171 .. 102 182 .. 0.70 4 ! 8.1 0.0 0.0035 1.4 40 126 .. 127 213 .. 120 220 .. 0.75 5 ! 7.5 0.3 0.005 2 42 128 .. 213 299 .. 210 302 .. 0.83 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 2.1 Beta-prop_IFT140_1st 96 elpklhkaeitvlewssn...g.srLvsgdksGvlvvWkl 131 + +++h+ +i +++w ++ g +++v+g ++ +W+ FUN_001898-T1 9 KQDQAHEDSIWTVAWGTSdkdGtENIVTGAVDDMVKCWRW 48 6678999999999998762232247999999999999985 PP == domain 2 score: 6.2 bits; conditional E-value: 0.013 Beta-prop_IFT140_1st 289 lLitatgesvirlwdlerddnyvLsldeklgfekgEaincvsyckakgiLaaGtnkGrvalwkkvaesssskkkegkek 367 l + ++ +s+ir+wdle+++ d +v+++ + +a+G G++ l + + +++ +++ k FUN_001898-T1 77 LAASSSLDSHIRIWDLESGKQLKAI-DC----GPV-DTWTVAFSPDSRFIATGSHAGKINLIGVESGK-KESALDTRGK 148 5566777999*******99875422.22....222.24678888888899999998888887766653.4445555555 PP == domain 3 score: 2.5 bits; conditional E-value: 0.18 Beta-prop_IFT140_1st 66 lsWHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvl 126 ++ P + +a+g G + ++ ++++++++ +++ + +++s g ++ g G++ FUN_001898-T1 111 VAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGII 171 4555677777777777777777777777777777777777777777777777777666665 PP == domain 4 score: 8.1 bits; conditional E-value: 0.0035 Beta-prop_IFT140_1st 40 GsvdlyleegekvedakiersvqvtvlsWHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvl 126 G+++l e k e+a +r ++++++ P + +a g +G + ++ ++++l ++ + h i l++s + L+++ ++ FUN_001898-T1 127 GKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHI 213 666666555555555566666677788888999999999999999999999999999999999999999999999999988665554 PP == domain 5 score: 7.5 bits; conditional E-value: 0.005 Beta-prop_IFT140_1st 42 vdlyleegekvedakiersvqvtvlsWHPtkkilavgwesGevlvlneqdkeltelpklhkaeitvlewssngsrLvsgdksGvlvv 128 +++y + +++ + + + v +s P +++ + + + v v+ ++++ ++ h+ ++ ++++++gs++vs +++v FUN_001898-T1 213 IKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIV 299 667777777777777777888888889999999999999999***********************************9755555555 PP >> Beta-prop_NUP159_NUP214 NUP159/214 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.052 20 62 142 .. 109 181 .. 98 185 .. 0.77 2 ! 18.2 0.0 4.3e-06 0.0017 62 218 .. 151 301 .. 144 303 .. 0.85 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.052 Beta-prop_NUP159_NUP214 62 ihvaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlkarsl 142 +vaFs d+ + +++ ++ g++ + ves + ke+a+ +t+g+ ++++ p+ ++ +a +g + ++dl +++l FUN_001898-T1 109 WTVAFSPDSRF-IATGSHAGKINLIGVESGK---KESAL--DTRGKFTMSIAYSPD--GHYIACGAIDGIINIFDLTTGKL 181 689******85.7779************999...45554..455556666666666..78888888888888888888876 PP == domain 2 score: 18.2 bits; conditional E-value: 4.3e-06 Beta-prop_NUP159_NUP214 62 ihvaFssdesalvilaeedgglavydveslekgnkepafslstngvsiralkpnpspeaellailtsngkLlladlkarslv...s 144 + +a+s d++ +++ dg + +d+++ + ++l+ + + ir+l+ p+ ++ll+ ++++ + ++d++ +l s FUN_001898-T1 151 MSIAYSPDGH-YIACGAIDGIINIFDLTTGK-----LLHTLEGHAMPIRSLTFSPD--SQLLITASDDNHIKIYDVQHANLAgtlS 228 6788999996.58889999*******99998.....78888888899*********..68********************998777 PP Beta-prop_NUP159_NUP214 145 vlkenvssfdwsnkgkqlvvgladgtaqqlkpadgevkaeiprpeeeeledesyephvssIswLendeflvvyg 218 + + v ++ ++ +v ++d+t+++ + + + +++ + +++ + +y+ + s+I+ ++ d+ ++vy FUN_001898-T1 229 GHGSWVLGVSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQ-VWGVKYNATGSKIVSVSDDKSVIVYN 301 7888899999999*******************988888888888883.43333666779999999889999985 PP >> Beta-prop_DCAF12 DDB1- and CUL4-associated factor 12 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 2.5 0.0076 2.9 103 148 .. 6 56 .. 2 68 .. 0.80 2 ? 2.2 0.1 0.26 99 110 144 .. 61 96 .. 57 108 .. 0.79 3 ! 17.1 0.1 7.4e-06 0.0029 62 159 .. 184 279 .. 161 298 .. 0.82 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0076 Beta-prop_DCAF12 103 lclGdrkghkdwifaiawls.d....tvavsGsrdgtlalwrvdpdklnas 148 +c+ ++h+d i ++aw + d +v+G++d + wr +dkl+ FUN_001898-T1 6 VCFKQDQAHEDSIWTVAWGTsDkdgtENIVTGAVDDMVKCWRWTEDKLHLR 56 799999************642422324689**************9998755 PP == domain 2 score: 2.2 bits; conditional E-value: 0.26 Beta-prop_DCAF12 110 ghkdwifaia.wlsdtvavsGsrdgtlalwrvdpdk 144 gh+ +++++ l+ t+a s s d+ + +w +++ k FUN_001898-T1 61 GHQLGVVSVDvNLTGTLAASSSLDSHIRIWDLESGK 96 6776666664258999**************999865 PP == domain 3 score: 17.1 bits; conditional E-value: 7.4e-06 Beta-prop_DCAF12 62 akaqpasGihaielnpsktllatgGenpnslavyqlPtldPlclGdrkghkdwifaiawlsdtv.avsGsrdgtlalwrvdpdklnasialkn 153 + + +a+ i+++ + p ll t+ + n + +y + + G gh w+ + + d+ vs s d t+ +w + + +++ +++ FUN_001898-T1 184 TLEGHAMPIRSLTFSPDSQLLITASD-DNHIKIYDVQHAN--LAGTLSGHGSWVLGVSFCPDNThFVSSSSDKTVKVWDAGSRQCVQTFYQHS 273 4556788999***********99876.6899***998765..46999*************886527**************9999999999999 PP Beta-prop_DCAF12 154 eaelpv 159 ++ v FUN_001898-T1 274 DQVWGV 279 887655 PP >> Beta-prop_RIG_1st RIG first beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 3.6 1.4e+03 62 75 .. 84 97 .. 67 100 .. 0.71 2 ! 11.0 0.0 0.00041 0.16 147 191 .. 154 197 .. 138 221 .. 0.85 3 ? 2.2 0.2 0.19 74 44 82 .. 232 272 .. 204 275 .. 0.58 4 ! 6.7 0.6 0.0082 3.2 24 70 .. 254 302 .. 245 304 .] 0.75 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 3.6 Beta-prop_RIG_1st 62 DlsvqvwDcalGea 75 D +++wD ++G+ FUN_001898-T1 84 DSHIRIWDLESGKQ 97 66677777777765 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00041 Beta-prop_RIG_1st 147 rcSPydenlfAvGTaaGlvlvcdlrkmsivyklrghkseisgLaW 191 SP d + +A G G++ + dl+ +++++l+gh i +L + FUN_001898-T1 154 AYSP-DGHYIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTF 197 5566.7899********************************9986 PP == domain 3 score: 2.2 bits; conditional E-value: 0.19 Beta-prop_RIG_1st 44 lWgkteea..eskafaivaeDlsvqvwDcalGeavkGHkaH 82 W+ + ++ +f+ D v+vwD + + v+ H FUN_001898-T1 232 SWVLGVSFcpDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQH 272 55544322446667777777777777777666666655555 PP == domain 4 score: 6.7 bits; conditional E-value: 0.0082 Beta-prop_RIG_1st 24 asevktmstrinilal..dvsplWgkteeaeskafaivaeDlsvqvwDc 70 +++v +r+ ++++ + Wg + +a++ +++ v +D sv v+ c FUN_001898-T1 254 TVKVWDAGSRQCVQTFyqHSDQVWGVKYNATGSKIVSVSDDKSVIVYNC 302 45555555677777663346889**999999999*************99 PP >> WD40_like WD40-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 1.4 5.5e+02 3 39 .. 66 102 .. 65 103 .. 0.90 2 ! 12.9 0.0 0.0002 0.076 4 74 .. 109 180 .. 106 189 .. 0.88 3 ? 2.7 0.0 0.24 94 3 59 .. 192 248 .. 190 268 .. 0.82 4 ? -0.5 0.0 2.3 9.1e+02 6 51 .. 237 282 .. 232 300 .. 0.78 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 1.4 WD40_like 3 vYsidlskkssliayGgkddkctlldlesleevsiie 39 v s+d++ ++l a + d ++++ dles ++ + i+ FUN_001898-T1 66 VVSVDVNLTGTLAASSSLDSHIRIWDLESGKQLKAID 102 679**************************99887765 PP == domain 2 score: 12.9 bits; conditional E-value: 0.0002 WD40_like 4 YsidlskkssliayGgkddkctlldlesleevsiie...sFsdsviyvkfldndlilvatlDGtilesllenee 74 +++ +s++s +ia G++ k+ l+ +es ++ s ++ +F+ s+ y+ d+ i ++++DG i +l+ ++ FUN_001898-T1 109 WTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDtrgKFTMSIAYSP--DGHYIACGAIDGIINIFDLTTGK 180 7899************************999998874446*******96..8999**********999998876 PP == domain 3 score: 2.7 bits; conditional E-value: 0.24 WD40_like 3 vYsidlskkssliayGgkddkctlldlesleevsiiesFsdsviyvkfldndlilva 59 + s+ +s++s+l++ ++d++++++d++ + + + + v+ v f +++ +v+ FUN_001898-T1 192 IRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDNTHFVS 248 568999**********************99999999888888888888866654443 PP == domain 4 score: -0.5 bits; conditional E-value: 2.3 WD40_like 6 idlskkssliayGgkddkctlldlesleevsiiesFsdsviyvkfl 51 + + ++++ ++ + d+++++ d s + v+ + + sd v vk+ FUN_001898-T1 237 VSFCPDNTHFVSSSSDKTVKVWDAGSRQCVQTFYQHSDQVWGVKYN 282 6677888999999999999999999999999999999999888864 PP >> Ge1_WD40 WD40 region of Ge1, enhancer of mRNA-decapping protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 1.2 4.6e+02 193 213 .. 111 131 .. 103 141 .. 0.88 2 ? 5.2 0.0 0.032 12 192 216 .. 152 176 .. 133 188 .. 0.85 3 ! 7.3 0.1 0.0074 2.9 185 217 .. 186 219 .. 179 299 .. 0.79 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 1.2 Ge1_WD40 193 aalspdGtalatasadGlvkf 213 a+spd +at s+ G + + FUN_001898-T1 111 VAFSPDSRFIATGSHAGKINL 131 68**************99865 PP == domain 2 score: 5.2 bits; conditional E-value: 0.032 Ge1_WD40 192 eaalspdGtalatasadGlvkffqi 216 + a+spdG +a + dG++ f + FUN_001898-T1 152 SIAYSPDGHYIACGAIDGIINIFDL 176 4589****************99875 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0074 Ge1_WD40 185 eeds.llveaalspdGtalatasadGlvkffqiy 217 e+++ + + ++spd l tas d ++k + + FUN_001898-T1 186 EGHAmPIRSLTFSPDSQLLITASDDNHIKIYDVQ 219 5666567788999999999999999999999875 PP >> WDR54 WDR54 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.5 1.9e+02 225 283 .. 34 94 .. 29 114 .. 0.72 2 ! 15.5 0.1 2.6e-05 0.01 224 307 .. 161 241 .. 149 261 .. 0.84 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.5 WDR54 225 iaagygngqvhlyeattgnlhvqina..haraicaldlasevgkllsagedtfvhiwklsr 283 i +g + v+ + t +lh++ n h ++++d+ s+ d+ ++iw l FUN_001898-T1 34 IVTGAVDDMVKCWRWTEDKLHLRFNFegHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLES 94 55666777888899999999999886115555566666554444456678999999*9975 PP == domain 2 score: 15.5 bits; conditional E-value: 2.6e-05 WDR54 224 iiaagygngqvhlyeattgnlhvqinaharaicaldlasevgkllsagedtfvhiwklsrnpesgyievehchgecvadtqlcg 307 ia+g +g + +++ ttg+l ++ ha i +l ++ + l++a +d ++i+ + + +g + hg v +c FUN_001898-T1 161 YIACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGTLS---GHGSWVLGVSFCP 241 5899999**************************************************99988888764...5677776666664 PP >> PEP5_VPS11_N PEP5/VPS11 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.31 1.2e+02 55 151 .. 53 132 .. 9 140 .. 0.61 2 ! 8.3 0.0 0.0038 1.5 35 102 .. 158 220 .. 134 232 .. 0.81 3 ? 2.9 0.1 0.18 68 32 90 .. 239 297 .. 232 301 .. 0.87 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.31 PEP5_VPS11_N 55 lkevrsfkayesgrvthlkqlkqsnlLvtigedesgsepvlKvWdldkldkktgapkclrtvkiqngnkpfpvsalavsedlsllavGfangsVll 150 l+ +f+ ++ v + nl t++ s+ ++ +++Wdl+ ++ l+ + p+ ++a+s+d ++a G g++ l FUN_001898-T1 53 LHLRFNFEGHQL-GVVSVD----VNLTGTLAA-SSSLDSHIRIWDLESGKQ-------LKAIDC----GPVDTWTVAFSPDSRFIATGSHAGKINL 131 555555555555.333333....255557777.445577888888887644.......222222....2566667777777777777777777766 PP PEP5_VPS11_N 151 i 151 i FUN_001898-T1 132 I 132 5 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0038 PEP5_VPS11_N 35 gsgslvlgdsdgtvhild.rslkevrsfkayesgrvthlkqlkqsnlLvtigedesgsepvlKvWdldk 102 ++ g dg ++i+d + k +++ + + + l+ ++s+lL+t ++d+ + +K++d+++ FUN_001898-T1 158 DGHYIACGAIDGIINIFDlTTGKLLHTLEGHAM-PIRSLTFSPDSQLLITASDDN-H----IKIYDVQH 220 34688899**********99999**********.****************88855.4....68888776 PP == domain 3 score: 2.9 bits; conditional E-value: 0.18 PEP5_VPS11_N 32 iasgsgslvlgdsdgtvhild.rslkevrsfkayesgrvthlkqlkqsnlLvtigedesg 90 +++ + + v +sd tv++ d s + v++f +++ +v +k+ + +v++++d+s FUN_001898-T1 239 FCPDNTHFVSSSSDKTVKVWDaGSRQCVQTFYQHSD-QVWGVKYNATGSKIVSVSDDKSV 297 67788899999999******9666778999999999.99999999999999***999875 PP >> WD_LRWD1 Leucine-rich repeat and WD repeat-containing protein 1, WD domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.0 0.0021 0.83 106 167 .. 162 222 .. 155 241 .. 0.87 2 ? 4.4 0.0 0.056 22 137 168 .. 235 265 .. 223 293 .. 0.77 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0021 WD_LRWD1 106 laaaglrgmvrllhvragfccsvirahkkaiatlcfspthethlftasydkriilwdigvpn 167 +a+ + g++ ++ + +g + h i +l fsp + l+tas d++i ++d+ n FUN_001898-T1 162 IACGAIDGIINIFDLTTGKLLHTLEGHAMPIRSLTFSPDSQ-LLITASDDNHIKIYDVQHAN 222 567778999999999999999999*************9765.6999********99998766 PP == domain 2 score: 4.4 bits; conditional E-value: 0.056 WD_LRWD1 137 atlcfspthethlftasydkriilwdigvpnh 168 + f p +th++++s dk + +wd g + FUN_001898-T1 235 LGVSFCP-DNTHFVSSSSDKTVKVWDAGSRQC 265 5566777.579***************998664 PP >> PALB2_WD40 Partner and localizer of BRCA2 WD40 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.33 1.3e+02 194 216 .. 83 105 .. 57 126 .. 0.78 2 ? -2.4 0.0 6.1 2.4e+03 198 213 .. 171 186 .. 161 216 .. 0.71 3 ! 10.7 0.1 0.00062 0.24 298 347 .] 253 301 .. 241 301 .. 0.92 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.33 PALB2_WD40 194 alnsiviwnlktGqllkklsiGn 216 + i iw+l +G+ lk ++ G FUN_001898-T1 83 LDSHIRIWDLESGKQLKAIDCGP 105 3456899*********9999885 PP == domain 2 score: -2.4 bits; conditional E-value: 6.1 PALB2_WD40 198 iviwnlktGqllkkls 213 i i++l tG+ll+ l+ FUN_001898-T1 171 INIFDLTTGKLLHTLE 186 4588888888888765 PP == domain 3 score: 10.7 bits; conditional E-value: 0.00062 PALB2_WD40 298 GaiavwdlllGhctallapesdeswslvkwsatdscllaGrkdGsvlvye 347 ++ vwd +c + +sd+ w vk+ at+s++++ d sv+vy+ FUN_001898-T1 253 KTVKVWDAGSRQCVQTFYQHSDQVWG-VKYNATGSKIVSVSDDKSVIVYN 301 5899*********************8.8********************95 PP >> Beta-prop_LRRK2 LRRK2 beta propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.021 8.1 290 321 .. 165 196 .. 77 207 .. 0.68 2 ? 4.2 0.0 0.067 26 222 248 .. 242 268 .. 204 274 .. 0.82 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.021 Beta-prop_LRRK2 290 GtggGhillldlstrqllqvisrhcdsvRsla 321 G +G i + dl+t +ll++++ h ++Rsl+ FUN_001898-T1 165 GAIDGIINIFDLTTGKLLHTLEGHAMPIRSLT 196 44455555555555555555555555555554 PP == domain 2 score: 4.2 bits; conditional E-value: 0.067 Beta-prop_LRRK2 222 dkyiylskknspvvevWdkkseklkel 248 d+ ++s ++++v vWd+ s++++++ FUN_001898-T1 242 DNTHFVSSSSDKTVKVWDAGSRQCVQT 268 78889**************99998875 PP >> KNTC1_N KNTC1, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.3 1.1 4.4e+02 182 226 .. 11 56 .. 3 94 .. 0.76 2 ? 5.1 0.0 0.041 16 72 99 .. 110 137 .. 104 141 .. 0.89 3 ? 5.2 0.0 0.038 15 42 100 .. 163 222 .. 153 227 .. 0.86 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.1 KNTC1_N 182 eevhtegvtslvtadlakk.ihliigGkGdsvLskWkldegekels 226 +++h+ ++ +++ + k+ ++ i+ G+ d ++ W++ e++ +l FUN_001898-T1 11 DQAHEDSIWTVAWGTSDKDgTENIVTGAVDDMVKCWRWTEDKLHLR 56 56777777777776555442678999************87776654 PP == domain 2 score: 5.1 bits; conditional E-value: 0.041 KNTC1_N 72 vvalsqdgqfLlvgersGnlhlihvesk 99 +va+s+d++f++ g + G++ li ves FUN_001898-T1 110 TVAFSPDSRFIATGSHAGKINLIGVESG 137 5899*******************99985 PP == domain 3 score: 5.2 bits; conditional E-value: 0.038 KNTC1_N 42 livvadksvslfdeicqsvlltLs.fdsevdvvalsqdgqfLlvgersGnlhlihveskk 100 ++ ++d + +fd + ++l tL+ ++ ++++s+d+q+L+ + + ++ +++v+ + FUN_001898-T1 163 ACGAIDGIINIFDLTTGKLLHTLEgHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHAN 222 56789999999999999999999846679*******************999999998765 PP >> Beta-prop_IFT140_2nd IFT140 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.24 94 121 140 .. 79 99 .. 65 103 .. 0.71 2 ? 4.0 0.0 0.08 31 117 135 .. 159 177 .. 150 192 .. 0.89 3 ? 2.3 0.0 0.27 1e+02 118 135 .. 202 219 .. 179 224 .. 0.85 4 ? 1.5 0.4 0.48 1.9e+02 32 54 .. 279 301 .. 248 303 .. 0.74 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.24 Beta-prop_IFT140_2nd 121 vvgtdngvikifDl.srReak 140 + ++ ++i+i+Dl s + k FUN_001898-T1 79 ASSSLDSHIRIWDLeSGKQLK 99 556778999999996666655 PP == domain 2 score: 4.0 bits; conditional E-value: 0.08 Beta-prop_IFT140_2nd 117 gsfLvvgtdngvikifDls 135 g++++ g g+i ifDl+ FUN_001898-T1 159 GHYIACGAIDGIINIFDLT 177 89****************7 PP == domain 3 score: 2.3 bits; conditional E-value: 0.27 Beta-prop_IFT140_2nd 118 sfLvvgtdngvikifDls 135 + L+ ++d +iki+D+ FUN_001898-T1 202 QLLITASDDNHIKIYDVQ 219 668999**********86 PP == domain 4 score: 1.5 bits; conditional E-value: 0.48 Beta-prop_IFT140_2nd 32 ikgvavtkdhvavwngkqvvvYe 54 +k a+ ++ v v ++k+v+vY+ FUN_001898-T1 279 VKYNATGSKIVSVSDDKSVIVYN 301 45556677888888888888886 PP >> DUF7037 Domain of unknown function (DUF7037) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 4.6 1.8e+03 11 22 .. 84 95 .. 83 98 .. 0.85 2 ? 5.6 0.1 0.055 21 10 21 .. 209 220 .. 206 221 .. 0.91 3 ? 4.6 0.0 0.12 45 9 19 .. 250 260 .. 244 268 .. 0.80 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 4.6 DUF7037 11 ddtvKiYTlehg 22 d ++ i++le g FUN_001898-T1 84 DSHIRIWDLESG 95 78999****965 PP == domain 2 score: 5.6 bits; conditional E-value: 0.055 DUF7037 10 dddtvKiYTleh 21 dd ++KiY++ h FUN_001898-T1 209 DDNHIKIYDVQH 220 89*******988 PP == domain 3 score: 4.6 bits; conditional E-value: 0.12 DUF7037 9 ldddtvKiYTl 19 +d+tvK+++ FUN_001898-T1 250 SSDKTVKVWDA 260 68*******96 PP >> Vgb_lyase Virginiamycin B lyase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00039 0.15 16 150 .. 109 243 .. 96 269 .. 0.61 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00039 Vgb_lyase 16 ygitagpdgalWftlvkagrigrltadgevteyeldtadagptvitagpdgalWfteskahrigrit.tdGevtefalptadsgPf.giaagpdga 109 ++++ +pd + t ++ag+i + ++ +e +ldt + i+ +pdg+ + + i ++ t+G++ ++l ++ P+ ++ pd + FUN_001898-T1 109 WTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMSIAYSPDGHYIACGAIDGIINIFDlTTGKL-LHTLE-GHAMPIrSLTFSPDSQ 202 4567777777777777777777777777777777777777777777777777655555555555443123333.23333.4455543566666666 PP Vgb_lyase 110 lWftemnadrigrittdgevtefelpvegafpsaitagpDg 150 l t+++ ++i +++ +l+ +g++ + pD+ FUN_001898-T1 203 LLITASDDNHIKIYDVQHANLAGTLSGHGSWVLGVSFCPDN 243 66666666666666665555555555555555555555554 PP >> Nucleoporin_N Nup133 N terminal like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.61 2.4e+02 217 236 .. 76 95 .. 9 107 .. 0.70 2 ? 1.2 0.0 0.42 1.6e+02 138 159 .. 148 172 .. 136 180 .. 0.80 3 ? 6.6 0.0 0.0099 3.8 205 242 .. 192 228 .. 186 261 .. 0.75 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.61 Nucleoporin_N 217 rllytltskgtirvydlspn 236 l + + +++ir++dl+++ FUN_001898-T1 76 TLAASSSLDSHIRIWDLESG 95 44444555777777777754 PP == domain 2 score: 1.2 bits; conditional E-value: 0.42 Nucleoporin_N 138 vvtdlinaepaGriflagstg...r 159 ++t+ i + p+G+++++g+ + + FUN_001898-T1 148 KFTMSIAYSPDGHYIACGAIDgiiN 172 7999**************9884444 PP == domain 3 score: 6.6 bits; conditional E-value: 0.0099 Nucleoporin_N 205 ivqlrvdssreerllytltskgtirvydls.pnggsslk 242 i +l+ ++ + +ll+t++ + +i++yd++ +n +l+ FUN_001898-T1 192 IRSLTFSPDS--QLLITASDDNHIKIYDVQhANLAGTLS 228 6777778888..******************666555555 PP >> PD40 WD40-like Beta Propeller Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.0 0.92 3.6e+02 15 24 .. 112 121 .. 110 121 .. 0.86 2 ? 5.1 0.0 0.087 34 11 24 .. 150 163 .. 142 163 .. 0.81 3 ? 2.2 0.0 0.7 2.7e+02 15 24 .. 196 205 .. 181 211 .. 0.85 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.92 PD40 15 sfSPDGkrla 24 +fSPD + +a FUN_001898-T1 112 AFSPDSRFIA 121 8****99886 PP == domain 2 score: 5.1 bits; conditional E-value: 0.087 PD40 11 etePsfSPDGkrla 24 ++ ++SPDG ++a FUN_001898-T1 150 TMSIAYSPDGHYIA 163 6899******9986 PP == domain 3 score: 2.2 bits; conditional E-value: 0.7 PD40 15 sfSPDGkrla 24 +fSPD + l+ FUN_001898-T1 196 TFSPDSQLLI 205 8****99886 PP >> Beta-prop_IFT122_2nd IFT122 second beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.0053 2.1 153 196 .. 183 226 .. 125 262 .. 0.67 2 ? 1.6 0.0 0.54 2.1e+02 153 187 .. 267 301 .. 262 303 .. 0.88 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0053 Beta-prop_IFT122_2nd 153 vellklkssvrclDlsasrkklavvdenskllvydlktkellfq 196 +l ++ ++r+l +s + + l ++ +++ +yd+++ +l + FUN_001898-T1 183 HTLEGHAMPIRSLTFSPDSQLLITASDDNHIKIYDVQHANLAGT 226 45566899*****************************9876544 PP == domain 2 score: 1.6 bits; conditional E-value: 0.54 Beta-prop_IFT122_2nd 153 vellklkssvrclDlsasrkklavvdenskllvyd 187 ++ ++++ +v + +a+ +k++ v++ ++++vy+ FUN_001898-T1 267 QTFYQHSDQVWGVKYNATGSKIVSVSDDKSVIVYN 301 567899999999**********************8 PP >> Chorion_S16 Chorion protein S16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.00077 0.3 23 107 .. 72 152 .. 66 153 .. 0.87 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00077 Chorion_S16 23 naagaaasaakldgadwyalnrygweqgrpllakpygpldklyaaalpprsfvaeidpvfkkseyggaygeksvtlntgaklava 107 n +g+ a+++ ld+ + + e g+ l a gp+d a p f+a k + g g+k+ l+t k++++ FUN_001898-T1 72 NLTGTLAASSSLDS----HIRIWDLESGKQLKAIDCGPVDTWTVAFSPDSRFIATGSHAGKINLIGVESGKKESALDTRGKFTMS 152 66677777777775....4666889****************9999999999***************************9998765 PP >> Beta-prop_pof12 F-box protein pof12 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.3 0.0013 0.49 291 326 .. 61 96 .. 48 119 .. 0.90 2 ? -0.1 0.0 1.3 5e+02 77 141 .. 159 220 .. 117 256 .. 0.68 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.0013 Beta-prop_pof12 291 GHTSsvsgvqvsdrGkAvSvSsrGdelRvWeLEglv 326 GH v +v+v+ G Ss +R+W+LE++ FUN_001898-T1 61 GHQLGVVSVDVNLTGTLAASSSLDSHIRIWDLESGK 96 99999***********999999***********985 PP == domain 2 score: -0.1 bits; conditional E-value: 1.3 Beta-prop_pof12 77 eievavGfedgsfsvyeldveesrlelrlshaassngaitalalsspylltvseeklLslYklee 141 + +a G dg +++++l + + l ++l+ +a+ +t + s l+t s+++ + +Y++++ FUN_001898-T1 159 GHYIACGAIDGIINIFDLTTGK--LLHTLEGHAMPIRSLT-FSPDSQLLITASDDNHIKIYDVQH 220 4566677777777777766443..2222222222222222.233455666666667777776644 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (304 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 721 (0.0282247); expected 510.9 (0.02) Passed bias filter: 614 (0.024036); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 66 (0.00258368); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 66 [number of targets reported over threshold] # CPU time: 0.61u 0.35s 00:00:00.96 Elapsed: 00:00:00.47 # Mc/sec: 2607.95 // Query: FUN_001899-T1 [L=77] Description: FUN_001899 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-13 51.9 0.0 1.1e-13 51.7 0.0 1.1 1 COX7C Cytochrome c oxidase subunit VIIc Domain annotation for each model (and alignments): >> COX7C Cytochrome c oxidase subunit VIIc # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.7 0.0 4.5e-18 1.1e-13 16 64 .] 25 73 .. 8 73 .. 0.85 Alignments for each domain: == domain 1 score: 51.7 bits; conditional E-value: 4.5e-18 COX7C 16 ssssHypegpysnlPFvvnnkipfavkywgffgvgFaaPFliaywQlkK 64 + +s ++egp++n+PF+++nk ++++ +++++g F +PF+++++Q+ K FUN_001899-T1 25 RLRSEFAEGPGNNMPFQTKNKPRLLATMILYLGGMFTLPFIAVRFQMAK 73 4447899****************************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (77 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 307 (0.012018); expected 510.9 (0.02) Passed bias filter: 253 (0.00990409); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 780.86 // Query: FUN_001900-T1 [L=181] Description: FUN_001900 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-11 45.2 0.0 2.7e-11 43.8 0.0 1.7 1 Ribosomal_L14 Ribosomal protein L14p/L23e Domain annotation for each model (and alignments): >> Ribosomal_L14 Ribosomal protein L14p/L23e # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.8 0.0 1.1e-15 2.7e-11 2 121 .. 67 180 .. 66 181 .] 0.78 Alignments for each domain: == domain 1 score: 43.8 bits; conditional E-value: 1.1e-15 Ribosomal_L14 2 iqvetvlnvaDNsG.Akevevikvlggk.......rrkyasvGDvivvsvkkakpkskvkkgdvvkavvvrtkkevrRkdGsvirfddNaaVlink 89 i + t+++v+DNs A++v+ + + +rk+a GD+i v++ +++ ka+v+ t+k+ k+ +v r+d+N +Vl+++ FUN_001900-T1 67 ITLLTTFKVIDNSAlAQRVKKNR---QPyligfyrKRKTADPGDLIRVAIAGKTN----------KALVIGTRKT---KHHTVPRYDNNCIVLVDD 146 5667999******6344443222...22233444467***********9965555..........9*******98...567899************ PP Ribosomal_L14 90 kgepkGtrifgpvarelrek..kflkivslApev 121 + p+Gtri+gpv++ +r++ k++k+++lA+++ FUN_001900-T1 147 NLAPLGTRIKGPVPTIIRRRqaKYSKVLALASRF 180 **************998665338********986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 490 (0.0191818); expected 510.9 (0.02) Passed bias filter: 452 (0.0176943); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1847.74 // Query: FUN_001900-T2 [L=158] Description: FUN_001900 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.3e-12 45.9 0.0 1.8e-11 44.4 0.0 1.7 1 Ribosomal_L14 Ribosomal protein L14p/L23e Domain annotation for each model (and alignments): >> Ribosomal_L14 Ribosomal protein L14p/L23e # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.4 0.0 7.1e-16 1.8e-11 2 121 .. 44 157 .. 43 158 .] 0.78 Alignments for each domain: == domain 1 score: 44.4 bits; conditional E-value: 7.1e-16 Ribosomal_L14 2 iqvetvlnvaDNsG.Akevevikvlggk.......rrkyasvGDvivvsvkkakpkskvkkgdvvkavvvrtkkevrRkdGsvirfddNaaVlink 89 i + t+++v+DNs A++v+ + + +rk+a GD+i v++ +++ ka+v+ t+k+ k+ +v r+d+N +Vl+++ FUN_001900-T2 44 ITLLTTFKVIDNSAlAQRVKKNR---QPyligfyrKRKTADPGDLIRVAIAGKTN----------KALVIGTRKT---KHHTVPRYDNNCIVLVDD 123 5667999******6344443222...22233444467***********9965555..........9*******98...567899************ PP Ribosomal_L14 90 kgepkGtrifgpvarelrek..kflkivslApev 121 + p+Gtri+gpv++ +r++ k++k+++lA+++ FUN_001900-T2 124 NLAPLGTRIKGPVPTIIRRRqaKYSKVLALASRF 157 **************998665338********986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (158 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 593 (0.0232139); expected 510.9 (0.02) Passed bias filter: 535 (0.0209434); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1558.63 // Query: FUN_001901-T1 [L=405] Description: FUN_001901 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-25 86.0 5.8 0.00011 22.4 0.0 9.7 9 LRR_6 Leucine Rich repeat 2.4e-20 72.9 25.0 1.2e-14 54.1 13.6 3.3 2 DUF7885 Leucine Rich Repeat Domain of unknown f 3e-12 46.6 3.0 1.2e-11 44.7 0.1 3.0 2 F-box-like F-box-like 8.1e-11 42.5 17.7 0.00036 20.8 0.2 3.4 4 LRR_At5g56370 FBD-associated F-box protein At5g56370, 1.3e-09 38.5 10.2 0.026 15.2 0.0 6.9 9 LRR_4 Leucine Rich repeats (2 copies) 6.6e-08 32.6 0.1 6.6e-08 32.6 0.1 4.3 6 F-box F-box domain 6.9e-06 26.2 23.6 6e-05 23.1 4.7 4.0 4 LRR_At1g61320_AtMIF1 At1g61320/AtMIF1, LRR domain 0.00021 20.4 23.6 0.12 11.2 5.3 4.1 5 LRR_FBXL18 F-box/LRR-repeat protein 18, LRR 0.00021 21.3 8.7 22 6.3 0.0 8.2 9 LRR_1 Leucine Rich Repeat 0.00023 21.8 0.0 1.1 9.9 0.0 2.8 2 HTH_34 Winged helix DNA-binding domain 0.0017 18.5 0.7 8 6.8 0.0 4.8 4 LRR_8 Leucine rich repeat ------ inclusion threshold ------ 0.091 13.3 0.0 0.25 11.8 0.0 1.7 1 DUF7706 Family of unknown function (DUF7706) 0.32 11.4 6.8 3.9 7.9 0.4 4.0 4 LRR_R13L1-DRL21 R13L1/DRL21 LRRs Domain annotation for each model (and alignments): >> LRR_6 Leucine Rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.18 3.5e+02 7 21 .. 100 115 .. 99 116 .. 0.90 2 ! 14.7 0.0 1.7e-05 0.033 2 23 .. 147 168 .. 146 169 .. 0.91 3 ? 1.5 0.0 0.28 5.6e+02 13 20 .. 210 217 .. 197 220 .. 0.77 4 ! 9.2 0.0 0.00099 1.9 2 18 .. 224 240 .. 223 246 .. 0.84 5 ? 4.0 0.0 0.044 87 2 23 .. 249 271 .. 248 272 .. 0.84 6 ? 5.3 0.0 0.017 34 2 23 .. 275 297 .. 274 298 .. 0.84 7 ! 22.4 0.0 5.8e-08 0.00011 1 23 [. 300 322 .. 300 323 .. 0.95 8 ! 16.1 0.0 6.2e-06 0.012 3 22 .. 327 347 .. 327 349 .. 0.92 9 ? 2.2 0.0 0.17 3.2e+02 2 18 .. 352 369 .. 351 370 .. 0.89 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.18 LRR_6 7 eLdLsgNd.IgDeGle 21 +Ld+s + I+ +Gl+ FUN_001901-T1 100 VLDVSECPnITEDGLI 115 69***********997 PP == domain 2 score: 14.7 bits; conditional E-value: 1.7e-05 LRR_6 2 nttLteLdLsgNdIgDeGleaL 23 + ++++Ld++ + ++D+Gl+ + FUN_001901-T1 147 CKKIKSLDITLCSVTDKGLQEF 168 8899***************976 PP == domain 3 score: 1.5 bits; conditional E-value: 0.28 LRR_6 13 NdIgDeGl 20 N IgDeG+ FUN_001901-T1 210 NLIGDEGV 217 44*****7 PP == domain 4 score: 9.2 bits; conditional E-value: 0.00099 LRR_6 2 nttLteLdLsgNdIgDe 18 +++L+ L L++++I+ FUN_001901-T1 224 CPSLERLQLNSCGITSQ 240 99************976 PP == domain 5 score: 4.0 bits; conditional E-value: 0.044 LRR_6 2 nttLteLdLsgNd.IgDeGleaL 23 + ++ +LdL+ + ++D+ +eaL FUN_001901-T1 249 CKNMSVLDLRRCStLTDDMVEAL 271 88999*******99999866666 PP == domain 6 score: 5.3 bits; conditional E-value: 0.017 LRR_6 2 nttLteLdLsgNd.IgDeGleaL 23 +++L+ L+Ls + ++D+ l+ + FUN_001901-T1 275 CQYLKLLNLSLCFhVTDTSLKYI 297 99**********77888877766 PP == domain 7 score: 22.4 bits; conditional E-value: 5.8e-08 LRR_6 1 hnttLteLdLsgNdIgDeGleaL 23 +++tL++L + +++I+D+Glea+ FUN_001901-T1 300 KCRTLRSLYMVHCKITDDGLEAF 322 69*******************98 PP == domain 8 score: 16.1 bits; conditional E-value: 6.2e-06 LRR_6 3 ttLteLdLsgNd.IgDeGlea 22 ++L+ Ld+s+++ ++D+G++ FUN_001901-T1 327 CNLERLDISWCQdVTDTGVQT 347 69****************985 PP == domain 9 score: 2.2 bits; conditional E-value: 0.17 LRR_6 2 nttLteLdLsgNd.IgDe 18 +++L++L L +d ++De FUN_001901-T1 352 CPYLKHLGLVRCDlVNDE 369 89***********88876 PP >> DUF7885 Leucine Rich Repeat Domain of unknown function (DUF7885) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 8.5 3.6e-07 0.00071 327 411 .. 106 192 .. 96 194 .. 0.86 2 ! 54.1 13.6 6e-18 1.2e-14 264 470 .. 172 375 .. 172 378 .. 0.90 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 3.6e-07 DUF7885 327 cslltsetai.slssCknlevldlsgCrsiadsGlasiskls.kltlldlaGaditdaGlsalGnGsspisslclrgCkritdrGia 411 c +t + i l C+ l l + C ++ d+ l+ i k + k+ +ld++ + +td+Gl +G+ ++++ l + C+ +t + ++ FUN_001901-T1 106 CPNITEDGLIkALWRCRLLVELTVVRCSAVTDECLSVIGKSCkKIKSLDITLCSVTDKGLQEFGKSCTRLEKLIMDQCRSLTSESLC 192 556666554416889*99999*******************994599*********************************99987765 PP == domain 2 score: 54.1 bits; conditional E-value: 6e-18 DUF7885 264 ckrlesvrlgGfskvrdaGyaallqsCkdlkkfevstasllsdltfldldeaatkltevrlvscslltsetaislss.CknlevldlsgCrsiads 358 c rle + + ++ ++ +sC l+ + v +l+ d ++++ +++++l ++l sc+ +ts+ta+++++ Ckn+ vldl C ++ d+ FUN_001901-T1 172 CTRLEKLIMDQCRSLTSESLCSVARSCPMLRWLSVEYDNLIGDEGVHEMVQSCPSLERLQLNSCG-ITSQTAVYIAQyCKNMSVLDLRRCSTLTDD 266 56666666666666777778999*****************************************9.7*******9744****************** PP DUF7885 359 Glasisklsk.ltlldla.GaditdaGlsalGnGsspisslclrgCkritdrGiaslllgsgvinktlvaldlgylprisdravvliakaceeiss 452 + ++ + ++ l ll+l+ +td+ l + + + sl + Ck itd G+ +l l ld+++ ++d+ v ++ k c +++ FUN_001901-T1 267 MVEALVNSCQyLKLLNLSlCFHVTDTSLKYIVSKCRTLRSLYMVHCK-ITDDGLEAFLHCV----CNLERLDISWCQDVTDTGVQTVLKGCPYLKH 357 ***9999997589999994569*********999999*********8.9*****9999754....45899************************** PP DUF7885 453 lClrncllitdaslealg 470 l l c l++d+++ l+ FUN_001901-T1 358 LGLVRCDLVNDETITDLT 375 ************998876 PP >> F-box-like F-box-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 0.1 5.9e-15 1.2e-11 1 43 [. 32 74 .. 32 78 .. 0.94 2 ? 0.3 0.8 0.42 8.3e+02 16 28 .. 186 198 .. 178 205 .. 0.87 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 5.9e-15 F-box-like 1 lsdLPdEiLlqIFsyLdpkdLlrlalVCrrWrelasddsLWrr 43 +++LP+ i ++I+syL+ +dL ++++V+++W+ d++LW+ FUN_001901-T1 32 INNLPHLIFVNILSYLSVEDLGSASCVSKYWYNSGLDPQLWKI 74 689**************************************95 PP == domain 2 score: 0.3 bits; conditional E-value: 0.42 F-box-like 16 LdpkdLlrlalVC 28 L+ ++L+++a+ C FUN_001901-T1 186 LTSESLCSVARSC 198 78899******99 PP >> LRR_At5g56370 FBD-associated F-box protein At5g56370, LRR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 2.9 9.8e-06 0.019 16 121 .. 101 202 .. 94 214 .. 0.75 2 ! 8.3 0.1 0.0012 2.3 72 96 .. 211 235 .. 197 242 .. 0.76 3 ! 15.2 2.0 9.1e-06 0.018 33 96 .. 221 286 .. 213 298 .. 0.80 4 ! 20.8 0.2 1.8e-07 0.00036 33 96 .. 298 363 .. 289 372 .. 0.86 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 9.8e-06 LRR_At5g56370 16 Lvlvnrpwpldlplpasllrcaslrrlylgvwrfdtdalpr..aasFpnLreLgLsrvsiserdLhalLarcpvLesLsllgsrnglrrlrirsrs 109 L++ ++p ++ l ++l rc+ l l++ ++ td+ + + s + + L++ +s++++ L+ ++c+ Le+L + ++r + s+s FUN_001901-T1 101 LDVSECPNITEDGLIKALWRCRLLVELTVVRCSAVTDECLSviGKSCKKIKSLDITLCSVTDKGLQEFGKSCTRLEKLIMDQCR------SLTSES 190 5666677777888999999****999999999876665544247899*******************************766544......356666 PP LRR_At5g56370 110 Lrcvllwesvle 121 L +v + +l+ FUN_001901-T1 191 LCSVARSCPMLR 202 666655444444 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0012 LRR_At5g56370 72 siserdLhalLarcpvLesLsllgs 96 i ++ +h ++++cp Le L+l ++ FUN_001901-T1 211 LIGDEGVHEMVQSCPSLERLQLNSC 235 5778899*************99765 PP == domain 3 score: 15.2 bits; conditional E-value: 9.1e-06 LRR_At5g56370 33 llrcaslrrlylgvwrfdt.dalpraasFpnLreLgLsrvs.iserdLhalLarcpvLesLsllgs 96 + +c+sl+rl+l ++ ++ +a+ a n+ L+L+r+s ++++ ++al+++c+ L+ L+l + FUN_001901-T1 221 VQSCPSLERLQLNSCGITSqTAVYIAQYCKNMSVLDLRRCStLTDDMVEALVNSCQYLKLLNLSLC 286 679*************95515555677899*******99872566777*************99654 PP == domain 4 score: 20.8 bits; conditional E-value: 1.8e-07 LRR_At5g56370 33 llrcaslrrlylgvwrfdtdalpraa.sFpnLreLgLsrv.siserdLhalLarcpvLesLsllgs 96 + +c++lr+ly+ +++++d l++ + + nL+ L++s + +++++ ++ +L++cp L++L l+++ FUN_001901-T1 298 VSKCRTLRSLYMVHCKITDDGLEAFLhCVCNLERLDISWCqDVTDTGVQTVLKGCPYLKHLGLVRC 363 678**************9999998763699*******977269******************99876 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.3 0.21 4.2e+02 10 33 .. 20 46 .. 15 54 .. 0.74 2 ? -3.4 0.0 9.6 1.9e+04 28 37 .. 101 110 .. 100 119 .. 0.59 3 ? 1.3 0.0 0.34 6.7e+02 19 31 .. 143 156 .. 124 163 .. 0.74 4 ? 3.4 0.1 0.071 1.4e+02 16 33 .. 165 183 .. 148 193 .. 0.60 5 ! 10.8 0.0 0.00035 0.68 2 37 .. 200 238 .. 199 243 .. 0.81 6 ! 15.2 0.0 1.3e-05 0.026 1 37 [. 225 264 .. 225 271 .. 0.87 7 ! 9.7 0.0 0.00077 1.5 3 38 .. 278 316 .. 276 322 .. 0.78 8 ! 12.0 0.0 0.00014 0.28 2 31 .. 303 335 .. 302 343 .. 0.83 9 ! 6.9 0.0 0.0055 11 2 36 .. 328 366 .. 327 376 .. 0.80 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.21 LRR_4 10 nNritdidp...lskLpnLetLdLsgN 33 +N++ d+ +++Lp+L +++ + FUN_001901-T1 20 DNQVDGADNcfaINNLPHLIFVNILSY 46 788888888866668****99998554 PP == domain 2 score: -3.4 bits; conditional E-value: 9.6 LRR_4 28 LdLsgNnkit 37 Ld+s +++it FUN_001901-T1 101 LDVSECPNIT 110 5555555554 PP == domain 3 score: 1.3 bits; conditional E-value: 0.34 LRR_4 19 lsk.LpnLetLdLs 31 ++k +++ ++Ld++ FUN_001901-T1 143 IGKsCKKIKSLDIT 156 44559******994 PP == domain 4 score: 3.4 bits; conditional E-value: 0.071 LRR_4 16 idplsk.LpnLetLdLsgN 33 +++++k +++Le+L + ++ FUN_001901-T1 165 LQEFGKsCTRLEKLIMDQC 183 3335566*******77666 PP == domain 5 score: 10.8 bits; conditional E-value: 0.00035 LRR_4 2 nLetLdLs.nNritdidpls...kLpnLetLdLsgNnkit 37 L+ L+ +N i d + + ++p+Le L L+++ it FUN_001901-T1 200 MLRWLSVEyDNLIGDEGVHEmvqSCPSLERLQLNSC-GIT 238 69999999999***9888445548*********888.665 PP == domain 6 score: 15.2 bits; conditional E-value: 1.3e-05 LRR_4 1 pnLetLdLsnNritdidp..lsk.LpnLetLdLsgNnkit 37 p+Le+L L+++ it+ +++ ++n+ +LdL ++ +t FUN_001901-T1 225 PSLERLQLNSCGITSQTAvyIAQyCKNMSVLDLRRCSTLT 264 79*************999877788*********8875555 PP == domain 7 score: 9.7 bits; conditional E-value: 0.00077 LRR_4 3 LetLdLs.nNritdidp...lskLpnLetLdLsgNnkitd 38 L+ L+Ls ++td ++ sk+ L++L++ ++ kitd FUN_001901-T1 278 LKLLNLSlCFHVTDTSLkyiVSKCRTLRSLYMVHC-KITD 316 56677774449***999874447*********999.9987 PP == domain 8 score: 12.0 bits; conditional E-value: 0.00014 LRR_4 2 nLetLdLsnNritdidp...lskLpnLetLdLs 31 L++L++ +++itd ++ l++ nLe Ld+s FUN_001901-T1 303 TLRSLYMVHCKITDDGLeafLHCVCNLERLDIS 335 69***********8666665557999*****93 PP == domain 9 score: 6.9 bits; conditional E-value: 0.0055 LRR_4 2 nLetLdLs.nNritdidp...lskLpnLetLdLsgNnki 36 nLe+Ld+s +td + l+++p L++L L ++ ++ FUN_001901-T1 328 NLERLDISwCQDVTDTGVqtvLKGCPYLKHLGLVRCDLV 366 9*******9779**9999998889*******99887444 PP >> F-box F-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.6 0.1 3.4e-11 6.6e-08 1 42 [. 32 73 .. 32 74 .. 0.94 2 ? -3.2 0.2 6.9 1.4e+04 26 34 .. 145 153 .. 138 153 .. 0.77 3 ? -2.7 0.1 5 9.8e+03 21 38 .. 165 182 .. 157 184 .. 0.74 4 ? -0.9 0.6 1.4 2.7e+03 25 40 .. 185 200 .. 185 203 .. 0.76 5 ? -0.4 0.1 0.95 1.9e+03 14 25 .. 250 261 .. 245 264 .. 0.79 6 ? -2.9 0.1 5.8 1.1e+04 7 21 .. 320 334 .. 319 337 .. 0.72 Alignments for each domain: == domain 1 score: 32.6 bits; conditional E-value: 3.4e-11 F-box 1 lldLPdellleIlsrLdpkdllrlslVSkrwrslvkslklwk 42 + +LP + +Ils+L++ dl ++s+VSk w++ ++ lwk FUN_001901-T1 32 INNLPHLIFVNILSYLSVEDLGSASCVSKYWYNSGLDPQLWK 73 679******************************999998886 PP == domain 2 score: -3.2 bits; conditional E-value: 6.9 F-box 26 lVSkrwrsl 34 + +k+ +sl FUN_001901-T1 145 KSCKKIKSL 153 779999986 PP == domain 3 score: -2.7 bits; conditional E-value: 5 F-box 21 llrlslVSkrwrslvksl 38 l + + ++r+ l+ ++ FUN_001901-T1 165 LQEFGKSCTRLEKLIMDQ 182 556778899999998776 PP == domain 4 score: -0.9 bits; conditional E-value: 1.4 F-box 25 slVSkrwrslvkslkl 40 sl+S +++s+++s++ FUN_001901-T1 185 SLTSESLCSVARSCPM 200 7888899988888765 PP == domain 5 score: -0.4 bits; conditional E-value: 0.95 F-box 14 srLdpkdllrls 25 +++++ dl r+s FUN_001901-T1 250 KNMSVLDLRRCS 261 578888888888 PP == domain 6 score: -2.9 bits; conditional E-value: 5.8 F-box 7 ellleIlsrLdpkdl 21 e+ l+++++L++ d+ FUN_001901-T1 320 EAFLHCVCNLERLDI 334 566788888888776 PP >> LRR_At1g61320_AtMIF1 At1g61320/AtMIF1, LRR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.2 0.22 4.4e+02 103 131 .. 108 136 .. 99 143 .. 0.89 2 ! 6.2 1.1 0.0042 8.3 91 132 .. 147 188 .. 141 208 .. 0.89 3 ! 7.7 0.5 0.0014 2.8 104 153 .. 212 263 .. 193 270 .. 0.77 4 ! 23.1 4.7 3e-08 6e-05 70 147 .. 273 357 .. 267 372 .. 0.72 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.22 LRR_At1g61320_AtMIF1 103 ritgdeLgclLsnslaLeeLelssCkeiv 131 +it+d L L ++ L eL++ +C+ ++ FUN_001901-T1 108 NITEDGLIKALWRCRLLVELTVVRCSAVT 136 69***********************9875 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0042 LRR_At1g61320_AtMIF1 91 lrsLtklhLssVritgdeLgclLsnslaLeeLelssCkeivc 132 ++++++l+++ ++t++ L+ + +++ Le+L + +C+++++ FUN_001901-T1 147 CKKIKSLDITLCSVTDKGLQEFGKSCTRLEKLIMDQCRSLTS 188 678999*******************************99875 PP == domain 3 score: 7.7 bits; conditional E-value: 0.0014 LRR_At1g61320_AtMIF1 104 itgdeLgclLsnslaLeeLelssC..keivcLkipcvLqrLsyLevlecskl 153 i ++ ++ ++ ++ +Le+L+l+sC ++ + + i+ +++s+L++ +cs+l FUN_001901-T1 212 IGDEGVHEMVQSCPSLERLQLNSCgiTSQTAVYIAQYCKNMSVLDLRRCSTL 263 5566678889999999999999993334566778887899999999999887 PP == domain 4 score: 23.1 bits; conditional E-value: 3e-08 LRR_At1g61320_AtMIF1 70 nsirsLeLssca..frptv.e....lgclrsLtklhLssVritgdeLgclLsnslaLeeLelssCkeivcLkipcvLqrLsyLev 147 ns ++L+L + + f+ t + ++ +r+L++l++ + +it+d L+ +L + Le+L++s C++++ + +vL+ yL+ FUN_001901-T1 273 NSCQYLKLLNLSlcFHVTDtSlkyiVSKCRTLRSLYMVHCKITDDGLEAFLHCVCNLERLDISWCQDVTDTGVQTVLKGCPYLKH 357 666666655443114444313122256789***************************************9999999976555443 PP >> LRR_FBXL18 F-box/LRR-repeat protein 18, LRR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 2.6 0.00044 0.87 7 68 .. 93 156 .. 87 162 .. 0.84 2 ! 9.4 4.1 0.00023 0.46 436 557 .. 161 276 .. 157 279 .. 0.83 3 ! 11.2 5.3 6.3e-05 0.12 286 345 .. 263 318 .. 249 327 .. 0.86 4 ! 9.9 3.3 0.00016 0.31 10 63 .. 276 330 .. 269 342 .. 0.56 5 ? 2.7 0.1 0.024 48 286 309 .. 340 363 .. 324 392 .. 0.73 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.00044 LRR_FBXL18 7 elakeiqslslsgcywls.gstvdqvarcrslvkldlsgcr.ltslrlskllsslsklrslald 68 + +++ + l++s+c ++ ++ + rcr lv+l + +c +t +ls + s +k++sl + FUN_001901-T1 93 NHGSNASVLDVSECPNITeDGLIKALWRCRLLVELTVVRCSaVTDECLSVIGKSCKKIKSLDIT 156 56778899******666516789*****************64899***************9875 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00023 LRR_FBXL18 436 Gdaevaalgk.laflrrltlaqlPgvlkGsglvqlalqckdlqvlslanlGslkkvnymsallellkhckqlkdlrleqPylsanaqffealsqcs 530 d+ + +gk ++l +l + q + l+ +l ++a +c l+ ls+ +++ +++ e+++ c l+ l+l+ +++ ++ + a +c+ FUN_001901-T1 161 TDKGLQEFGKsCTRLEKLIMDQCRS-LTSESLCSVARSCPMLRWLSVEYDNLIG----DEGVHEMVQSCPSLERLQLNSCGITSQTAVYIA-QYCK 250 5555555554257788888888766.78899***************98777666....58999*******************999999988.6899 PP LRR_FBXL18 531 alqrlclvsrsGtlqpeavlafmascl 557 + l l r+ tl + v+a+++sc+ FUN_001901-T1 251 NMSVLDL-RRCSTLTDDMVEALVNSCQ 276 9999986.899**************97 PP == domain 3 score: 11.2 bits; conditional E-value: 6.3e-05 LRR_FBXL18 286 ldssiletlvaacpnlkhlnlsaahhhsseglekhlcallarlkhlrslalPvcaladea 345 l ++e+lv++c +lk lnls + h + ++ l ++++ ++lrsl + c ++d+ FUN_001901-T1 263 LTDDMVEALVNSCQYLKLLNLSLCFHVT----DTSLKYIVSKCRTLRSLYMVHCKITDDG 318 566789******************9975....556778999***************9975 PP == domain 4 score: 9.9 bits; conditional E-value: 0.00016 LRR_FBXL18 10 keiqslslsgcywlsgstvdq.varcrslvkldlsgcrltslrlskllsslsklr 63 + ++ l+ls c++++ + ++ v +cr+l l + c++t l +l ++++l FUN_001901-T1 276 QYLKLLNLSLCFHVTDTSLKYiVSKCRTLRSLYMVHCKITDDGLEAFLHCVCNLE 330 3345566666666665555541345666666666666666666666666666655 PP == domain 5 score: 2.7 bits; conditional E-value: 0.024 LRR_FBXL18 286 ldssiletlvaacpnlkhlnlsaa 309 + + ++t+++ cp+lkhl l + FUN_001901-T1 340 VTDTGVQTVLKGCPYLKHLGLVRC 363 444556667777777777766554 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.6 3.2e+03 4 13 .. 100 111 .. 97 121 .. 0.71 2 ? 0.9 0.0 0.73 1.4e+03 2 22 .. 150 170 .. 149 171 .. 0.86 3 ? -0.8 0.0 2.7 5.2e+03 2 18 .. 175 189 .. 174 194 .. 0.71 4 ? 4.1 0.0 0.064 1.3e+02 1 15 [. 226 240 .. 226 247 .. 0.84 5 ? -0.4 0.0 2.1 4e+03 2 11 .. 252 261 .. 251 271 .. 0.80 6 ? -1.2 0.2 3.7 7.2e+03 2 11 .. 278 287 .. 277 295 .. 0.80 7 ? 6.3 0.0 0.011 22 2 22 .. 304 324 .. 303 325 .. 0.87 8 ? 4.1 0.0 0.062 1.2e+02 1 11 [. 328 338 .. 328 347 .. 0.87 9 ? -0.8 0.0 2.8 5.5e+03 2 13 .. 355 367 .. 354 376 .. 0.73 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.6 LRR_1 4 eLdLsnNnl..s 13 +Ld+s ++ + FUN_001901-T1 100 VLDVSECPNitE 111 79*****98543 PP == domain 2 score: 0.9 bits; conditional E-value: 0.73 LRR_1 2 LeeLdLsnNnlsgllpeslgn 22 +++Ld+ ++ +++ + ++g+ FUN_001901-T1 150 IKSLDITLCSVTDKGLQEFGK 170 799********9999988875 PP == domain 3 score: -0.8 bits; conditional E-value: 2.7 LRR_1 2 LeeLdLsnNnlsgllpe 18 Le+L ++ ++ + +e FUN_001901-T1 175 LEKLIMDQCRSL--TSE 189 999999999973..344 PP == domain 4 score: 4.1 bits; conditional E-value: 0.064 LRR_1 1 nLeeLdLsnNnlsgl 15 +Le+L L+++ ++++ FUN_001901-T1 226 SLERLQLNSCGITSQ 240 79**********855 PP == domain 5 score: -0.4 bits; conditional E-value: 2.1 LRR_1 2 LeeLdLsnNn 11 +LdL++++ FUN_001901-T1 252 MSVLDLRRCS 261 578****997 PP == domain 6 score: -1.2 bits; conditional E-value: 3.7 LRR_1 2 LeeLdLsnNn 11 L+ L+Ls + FUN_001901-T1 278 LKLLNLSLCF 287 8899999875 PP == domain 7 score: 6.3 bits; conditional E-value: 0.011 LRR_1 2 LeeLdLsnNnlsgllpeslgn 22 L++L++ ++++++ +e++ + FUN_001901-T1 304 LRSLYMVHCKITDDGLEAFLH 324 9**********9999998866 PP == domain 8 score: 4.1 bits; conditional E-value: 0.062 LRR_1 1 nLeeLdLsnNn 11 nLe+Ld+s ++ FUN_001901-T1 328 NLERLDISWCQ 338 8*********8 PP == domain 9 score: -0.8 bits; conditional E-value: 2.8 LRR_1 2 LeeLdLsnNnl.s 13 L++L L ++ l + FUN_001901-T1 355 LKHLGLVRCDLvN 367 9999999999943 PP >> HTH_34 Winged helix DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.0 0.00058 1.1 55 80 .] 154 179 .. 143 179 .. 0.86 2 ! 8.7 0.0 0.0014 2.7 42 78 .. 295 331 .. 291 332 .. 0.81 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00058 HTH_34 55 prtllriTpeGreafekyvkaLkelv 80 tl+++T++G+++f k + L++l+ FUN_001901-T1 154 DITLCSVTDKGLQEFGKSCTRLEKLI 179 589*******************9986 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0014 HTH_34 42 gYievdksfkgrkprtllriTpeGreafekyvkaLke 78 +Yi+ + + +++iT++G+eaf + v +L++ FUN_001901-T1 295 KYIVSKCRTLRSLYMVHCKITDDGLEAFLHCVCNLER 331 56666666666677899************99999887 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.98 1.9e+03 47 61 .] 197 211 .. 193 212 .. 0.82 2 ? 1.6 0.0 0.17 3.3e+02 45 60 .. 221 236 .. 215 237 .. 0.72 3 ? 2.3 0.3 0.11 2.1e+02 2 33 .. 251 284 .. 250 285 .. 0.87 4 ! 6.8 0.0 0.004 8 1 33 [. 302 335 .. 302 365 .. 0.75 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.98 LRR_8 47 gLpsLrsLdLsgNrL 61 +p Lr+L++++++L FUN_001901-T1 197 SCPMLRWLSVEYDNL 211 67999***9999765 PP == domain 2 score: 1.6 bits; conditional E-value: 0.17 LRR_8 45 fsgLpsLrsLdLsgNr 60 + +psL+ L L+++ FUN_001901-T1 221 VQSCPSLERLQLNSCG 236 5677888888888775 PP == domain 3 score: 2.3 bits; conditional E-value: 0.11 LRR_8 2 nLrsLdLssNr.ltslddgaFkg.lsnLkvLdLs 33 n +LdL++ + lt+ +a + ++ Lk L+Ls FUN_001901-T1 251 NMSVLDLRRCStLTDDMVEALVNsCQYLKLLNLS 284 677899999999999999999999*********8 PP == domain 4 score: 6.8 bits; conditional E-value: 0.004 LRR_8 1 pnLrsLdLssNrltslddgaFkg.lsnLkvLdLs 33 ++LrsL+ + ++t+ + +aF + nL++Ld+s FUN_001901-T1 302 RTLRSLYMVHCKITDDGLEAFLHcVCNLERLDIS 335 589********************999******98 PP >> DUF7706 Family of unknown function (DUF7706) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.00013 0.25 11 37 .. 237 263 .. 229 271 .. 0.88 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00013 DUF7706 11 LsdeeAlaLAqfvKRitfsdiRelAvd 37 +++++A+ Aq++K+++ d+R++++ FUN_001901-T1 237 ITSQTAVYIAQYCKNMSVLDLRRCSTL 263 6899********************974 PP >> LRR_R13L1-DRL21 R13L1/DRL21 LRRs # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.5 2.9e+03 103 126 .. 28 51 .. 26 52 .. 0.84 2 ? 0.3 0.1 0.45 8.9e+02 91 109 .. 170 188 .. 131 208 .. 0.70 3 ? 7.9 0.4 0.002 3.9 53 123 .. 209 282 .. 196 286 .. 0.75 4 ? 3.3 0.0 0.051 1e+02 92 125 .. 325 361 .. 319 363 .. 0.74 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.5 LRR_R13L1-DRL21 103 ncknleslpslgqLpsLkeLeiee 126 nc +++lp+l ++ L++L++e+ FUN_001901-T1 28 NCFAINNLPHLIFVNILSYLSVED 51 788899999999999999999876 PP == domain 2 score: 0.3 bits; conditional E-value: 0.45 LRR_R13L1-DRL21 91 sslsnLvsleLsncknles 109 +s ++L++l + +c++l+s FUN_001901-T1 170 KSCTRLEKLIMDQCRSLTS 188 6778899999999988865 PP == domain 3 score: 7.9 bits; conditional E-value: 0.002 LRR_R13L1-DRL21 53 sksekeeevleaLqPhsnLkeLkikgykGskfpswledsslsnLvsleLsncknlesl..ps.lgqLpsLkeLe 123 ++ +e v e q ++L++L++++ + ++ ++ +n+ l+L++c+ l++ + +++ + Lk L+ FUN_001901-T1 209 DNLIGDEGVHEMVQSCPSLERLQLNSCGITSQTAVYIAQYCKNMSVLDLRRCSTLTDDmvEAlVNSCQYLKLLN 282 555567889999*************9998888777789**************9987642233133355555555 PP == domain 4 score: 3.3 bits; conditional E-value: 0.051 LRR_R13L1-DRL21 92 slsnLvsleLsncknlesl...pslgqLpsLkeLeie 125 ++ nL++l++s c+ +++ l+ p Lk+L + FUN_001901-T1 325 CVCNLERLDISWCQDVTDTgvqTVLKGCPYLKHLGLV 361 5669999999999999887653447788888888776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (405 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 885 (0.0346447); expected 510.9 (0.02) Passed bias filter: 580 (0.022705); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 4012.28 // Query: FUN_001902-T1 [L=643] Description: FUN_001902 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-33 115.5 1.6 6.7e-33 114.7 1.6 1.4 1 Peptidase_S8 Subtilase family 8.7e-29 100.0 0.5 1.7e-28 99.1 0.5 1.5 1 P_proprotein Proprotein convertase P-domain ------ inclusion threshold ------ 0.15 12.1 0.0 0.19 11.7 0.0 1.2 1 Metalloenzyme Metalloenzyme superfamily Domain annotation for each model (and alignments): >> Peptidase_S8 Subtilase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 114.7 1.6 7.8e-37 6.7e-33 58 287 .] 37 271 .. 37 271 .. 0.86 Alignments for each domain: == domain 1 score: 114.7 bits; conditional E-value: 7.8e-37 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx...xxxxxxxxxx RF Peptidase_S8 58 thvAGiiaagannsagvsGvapgakilavkvggsgslsdaitakaierainqgarvinlSlGs...gktkggpsslseavdql...sgaeekgslf 147 t++AG+iaa + n+ +++Gva+gak+ +v++ +g ++d+++a a ++ + +++++ S+G+ gkt++gp +l++a+ + g++ gs+f FUN_001902-T1 37 TMCAGEIAAVP-NTYCAVGVAYGAKVSGVRI-LDGPMTDSLEAMAFNSK-MHVNDIYSCSWGPddnGKTVDGPHQLAQAALAHgvlAGRKGYGSIF 129 89********6.8******************.9*********9999999.8999************************666655677888888*** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_S8 148 VvAaGNespsgnaastvsaPaqyknviaVgavdeasegklasfSsrgpeldgaikpdivapGgneaegnsstlltttsdpanqkydsmsGTSmAtP 243 VvA+GN+ +++ + a++ +++++gavd + g++ ++ +++ + +++ g+ ++ n +t ++ ++++++d+++GTS+A+P FUN_001902-T1 130 VVASGNG-GHFKDNCNFDGYANSIYTVTIGAVD--ELGDMPYYAEHCAAM-----FAVTFSSGQGMQRNIVTTDW-RLGTGTGCTDKHTGTSAAAP 216 *******.5555555666667777*********..************999.....88888885533332222212.2245789************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxx RF Peptidase_S8 244 hvagaaAllksanpsltpeelkallvnta...........tdlgdagldrrfGyG 287 ++ag++Al+++a+p l+++++++++ ++ t++++ + ++++G+G FUN_001902-T1 217 LAAGMIALMLQARPCLSWRDVQHIIAISSvkhdvddddyhTNGAGYHHSHKYGFG 271 *************************999999999999998888999999999998 PP >> P_proprotein Proprotein convertase P-domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 99.1 0.5 1.9e-32 1.7e-28 1 86 [] 329 415 .. 329 415 .. 0.98 Alignments for each domain: == domain 1 score: 99.1 bits; conditional E-value: 1.9e-32 P_proprotein 1 lehvqvsvnithtrrgdlrieLisPsGtrsvLlnrrgkdksrsgfldwtfmsvahwgeeaeGeWkLevkd.tepedtgtlesWqLkl 86 lehv+v+vn++h +rg+l + L+s +Gt+s L+++r++dks+sgf+dwtf++v++wge+++G+W+L v d +++ g+l++W+L++ FUN_001902-T1 329 LEHVTVTVNLQHHYRGNLAVSLVSAEGTTSKLATARQHDKSSSGFVDWTFSTVRCWGEKPQGTWQLIVVDnGFDKSRGYLKDWKLTF 415 69********************************************************************88999**********97 PP >> Metalloenzyme Metalloenzyme superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 2.2e-05 0.19 61 128 .. 225 363 .. 73 376 .. 0.80 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 2.2e-05 x.........................................................................xxxxxxxxxxxxxxxxxxxxxx RF Metalloenzyme 61 l.........................................................................lrgpgelantpgefleknglkq 83 + ++ +++++++ ek+ +++ FUN_001902-T1 225 MlqarpclswrdvqhiiaissvkhdvddddyhtngagyhhshkygfglldswrlvntakawaavpwmtswstpvINVGKQIPSSSNRLVEKYHVTD 320 145555555566666666666666666666666666666666666677777777777777777777777777777788999*************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Metalloenzyme 84 ariaetekikhvtkfvnggveeefkgedvieiesatgitydlkpe 128 +i e++ ++hvt vn ++++++g ++ sa+g+t +l++ FUN_001902-T1 321 DKIKEVVTLEHVTVTVN--LQHHYRGNLAVSLVSAEGTTSKLATA 363 *****************..********************998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (643 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 865 (0.0338618); expected 510.9 (0.02) Passed bias filter: 675 (0.026424); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.36u 0.39s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 6220.81 // Query: FUN_001902-T2 [L=833] Description: FUN_001902 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-49 168.7 4.2 3.7e-49 168.0 4.2 1.3 1 Peptidase_S8 Subtilase family 9.1e-29 99.9 0.5 2.4e-28 98.6 0.5 1.8 1 P_proprotein Proprotein convertase P-domain 4e-17 63.1 0.1 1.3e-16 61.5 0.1 1.9 1 S8_pro-domain Peptidase S8 pro-domain ------ inclusion threshold ------ 0.16 11.9 0.0 0.19 11.7 0.0 1.2 1 Metalloenzyme Metalloenzyme superfamily Domain annotation for each model (and alignments): >> Peptidase_S8 Subtilase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 168.0 4.2 5.9e-53 3.7e-49 1 287 [] 175 461 .. 175 461 .. 0.89 Alignments for each domain: == domain 1 score: 168.0 bits; conditional E-value: 5.9e-53 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_S8 1 gkgvvvavlDtGidtshpdlsgnllkfvddaeasesvnnewgeedpessakdkngHGthvAGiiaagannsagvsGvapgakilavkvggsgslsd 96 g+gvvv+v+D+G+++++pd+ +n+ ++e+s++ n+++++++p+ ++ n HGt++AG+iaa + n+ +++Gva+gak+ +v++ +g ++d FUN_001902-T2 175 GHGVVVSVIDDGVEWTNPDILDNY-----CPEGSWDINSNDDDPMPRADEAGLNHHGTRCAGEIAAVP-NTYCAVGVAYGAKVSGVRI-LDGPMTD 263 78**********************.....9*************************************6.8******************.9****** PP xxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Peptidase_S8 97 aitakaierainqgarvinlSlGs...gktkggpsslseavdql...sgaeekgslfVvAaGNespsgnaastvsaPaqyknviaVgavdeasegk 186 +++a a ++ + +++++ S+G+ gkt++gp +l++a+ + g++ gs+fVvA+GN+ +++ + a++ +++++gavd + g+ FUN_001902-T2 264 SLEAMAFNSK-MHVNDIYSCSWGPddnGKTVDGPHQLAQAALAHgvlAGRKGYGSIFVVASGNG-GHFKDNCNFDGYANSIYTVTIGAVD--ELGD 355 ***9999999.8999************************666655677888888**********.5555555666667777*********..**** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......... RF Peptidase_S8 187 lasfSsrgpeldgaikpdivapGgneaegnsstlltttsdpanqkydsmsGTSmAtPhvagaaAllksanpsltpeelkallvnta.......... 272 + ++ +++ + +++ g+ ++ n +t ++ ++++++d+++GTS+A+P++ag++Al+++a+p l+++++++++ ++ FUN_001902-T2 356 MPYYAEHCAAM-----FAVTFSSGQGMQRNIVTTDW-RLGTGTGCTDKHTGTSAAAPLAAGMIALMLQARPCLSWRDVQHIIAISSvkhdvddddy 445 ********999.....88888885533332222212.2245789**************************************99999999999999 PP .xxxxxxxxxxxxxxx RF Peptidase_S8 273 .tdlgdagldrrfGyG 287 t++++ + ++++G+G FUN_001902-T2 446 hTNGAGYHHSHKYGFG 461 8888999999999998 PP >> P_proprotein Proprotein convertase P-domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.6 0.5 3.7e-32 2.4e-28 1 86 [] 519 605 .. 519 605 .. 0.98 Alignments for each domain: == domain 1 score: 98.6 bits; conditional E-value: 3.7e-32 P_proprotein 1 lehvqvsvnithtrrgdlrieLisPsGtrsvLlnrrgkdksrsgfldwtfmsvahwgeeaeGeWkLevkd.tepedtgtlesWqLkl 86 lehv+v+vn++h +rg+l + L+s +Gt+s L+++r++dks+sgf+dwtf++v++wge+++G+W+L v d +++ g+l++W+L++ FUN_001902-T2 519 LEHVTVTVNLQHHYRGNLAVSLVSAEGTTSKLATARQHDKSSSGFVDWTFSTVRCWGEKPQGTWQLIVVDnGFDKSRGYLKDWKLTF 605 69********************************************************************88999**********97 PP >> S8_pro-domain Peptidase S8 pro-domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.5 0.1 2e-20 1.3e-16 1 79 [] 47 138 .. 47 138 .. 0.89 Alignments for each domain: == domain 1 score: 61.5 bits; conditional E-value: 2e-20 S8_pro-domain 1 eWaVrlkegg.......eeeAdriAekhGfenlgqigeledyYlfkhrrvkkrskrslrhkr......eerLkkdpkVkwaeqqrvlkRvkR 79 +WaVr+ g+ + AdriA+++G++n+gqig+l ++Ylf+h++ +rs ++ ++ + ++ L+k+pk++w q+ v+ R kR FUN_001902-T2 47 SWAVRIPVGHyfnmsnlHALADRIADEAGLVNRGQIGGLVGHYLFVHDTFFNRSGSKRNDLSrvqgsiTKHLAKHPKIEWSRQEIVRMRYKR 138 6*****55559999985555***************************999999987775554577999***********************9 PP >> Metalloenzyme Metalloenzyme superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 3e-05 0.19 61 128 .. 410 553 .. 75 566 .. 0.80 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3e-05 x..............................................................................xxxxxxxxxxxxxxxxx RF Metalloenzyme 61 l..............................................................................lrgpgelantpgeflek 78 ++ +++++++ ek FUN_001902-T2 410 GmialmlqarpclswrdvqhiiaissvkhdvddddyhtngagyhhshkygfglldswrlvntakawaavpwmtswstpvINVGKQIPSSSNRLVEK 505 14445556666666666666677777777777777777777777777777777777777777777777777777788878888999********** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Metalloenzyme 79 nglkqariaetekikhvtkfvnggveeefkgedvieiesatgitydlkpe 128 + +++ +i e++ ++hvt vn ++++++g ++ sa+g+t +l++ FUN_001902-T2 506 YHVTDDKIKEVVTLEHVTVTVN--LQHHYRGNLAVSLVSAEGTTSKLATA 553 **********************..********************998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (833 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 878 (0.0343707); expected 510.9 (0.02) Passed bias filter: 726 (0.0284204); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 7902.04 // Query: FUN_001903-T1 [L=108] Description: FUN_001903 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-24 86.1 0.2 2.4e-24 85.8 0.2 1.1 1 Acetyltransf_CG GCN5-related N-acetyl-transferase 4.8e-06 27.3 0.1 6.6e-06 26.9 0.1 1.3 1 Acetyltransf_1 Acetyltransferase (GNAT) family 8.3e-05 23.1 0.1 0.00013 22.4 0.1 1.4 1 Acetyltransf_10 Acetyltransferase (GNAT) domain 0.00034 21.4 0.0 0.00047 21.0 0.0 1.2 1 Acetyltransf_7 Acetyltransferase (GNAT) domain 0.0084 16.0 0.0 0.0089 15.9 0.0 1.2 1 Acetyltransf_15 Putative acetyl-transferase ------ inclusion threshold ------ 0.16 13.2 0.1 0.25 12.5 0.1 1.6 1 Acetyltransf_3 Acetyltransferase (GNAT) domain Domain annotation for each model (and alignments): >> Acetyltransf_CG GCN5-related N-acetyl-transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.8 0.2 5.5e-28 2.4e-24 2 77 .. 28 100 .. 27 106 .. 0.92 Alignments for each domain: == domain 1 score: 85.8 bits; conditional E-value: 5.5e-28 Acetyltransf_CG 2 felrvdgegaevafleYeerkdgvlvldhTeVppalrGqGlAskLvkaalddareeglkvvplCsyvaaylekhpe 77 f+++++ +g +a+l+Ye+++d++l+++hTeVp a+rGqG+A++L+kaald+a +++ kv+ +Csy+++y++++p FUN_001903-T1 28 FYIALE-KG--KAVLQYENEGDKTLNMYHTEVPSAYRGQGIARHLAKAALDYAVDQDAKVKLTCSYLQKYVKDNPV 100 889997.44..4**************************************************************94 PP >> Acetyltransf_1 Acetyltransferase (GNAT) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.1 1.6e-09 6.6e-06 34 100 .. 27 88 .. 6 95 .. 0.76 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 1.6e-09 Acetyltransf_1 34 gflvaeedgelvGfaglsildeaekvaeieglaVdpeyrgkGiGtaLlealleyarergcerlylev 100 f++a e G a l ++e+ k+ ++ V ++yrg+Gi+++L +a+l+ya +++++ l++ FUN_001903-T1 27 EFYIALEK----GKAVLQYENEGDKTLNMYHTEVPSAYRGQGIARHLAKAALDYAVDQDAKV-KLTC 88 55555555....344444444455999999999*************************8865.7755 PP >> Acetyltransf_10 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.1 3.2e-08 0.00013 24 92 .. 19 89 .. 3 96 .. 0.76 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 3.2e-08 Acetyltransf_10 24 erieegeklllvaeedgeivGviel.rdns.hlsllfVdkeyqgqGiakaLlkaveeeaekddieleltvn 92 r + ++ ++++a e+g+ v e d++ +++ V ++y+gqGia+ L ka+++ a ++d++ +lt++ FUN_001903-T1 19 VRHDVKAREFYIALEKGKAVLQYENeGDKTlNMYHTEVPSAYRGQGIARHLAKAALDYAVDQDAKVKLTCS 89 4444455667777777776655555344447999999*********************9999998899885 PP >> Acetyltransf_7 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 1.1e-07 0.00047 3 64 .. 26 86 .. 24 101 .. 0.65 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 1.1e-07 Acetyltransf_7 3 erffVaeedgkivGfaallpeddeaalaeerla...VdpeyrgkGiGraLleaa.eaaa.kekgikl 64 +f++a e+gk v ++++ e+d++ ++ ++ V +yrg+Gi+r L +aa ++a +++++kl FUN_001903-T1 26 REFYIALEKGKAV--LQYENEGDKT--LN--MYhteVPSAYRGQGIARHLAKAAlDYAVdQDAKVKL 86 5788887766664..2334444444..45..66666****************997666554444433 PP >> Acetyltransf_15 Putative acetyl-transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 2.1e-06 0.0089 68 101 .. 44 77 .. 13 101 .. 0.81 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.1e-06 Acetyltransf_15 68 eeknvveiYslyvsekyrgkGlskklLlealsel 101 e + +++Y v++ yrg+G++++l + al++ FUN_001903-T1 44 EGDKTLNMYHTEVPSAYRGQGIARHLAKAALDYA 77 556899******************9999888765 PP >> Acetyltransf_3 Acetyltransferase (GNAT) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 6e-05 0.25 89 120 .. 57 89 .. 2 98 .. 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 6e-05 Acetyltransf_3 89 pe.ywgkGyatEavralleyafeelglerlvae 120 p+ y+g+G+a+ ++a+l+ya ++ +l++ FUN_001903-T1 57 PSaYRGQGIARHLAKAALDYAVDQDAKVKLTCS 89 5559*****************887766566655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (108 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 611 (0.0239186); expected 510.9 (0.02) Passed bias filter: 482 (0.0188687); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1099.40 // Query: FUN_001904-T1 [L=219] Description: FUN_001904 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-50 171.6 0.1 1.6e-50 171.3 0.1 1.1 1 Ras Ras family 1.4e-28 100.0 0.1 2.2e-28 99.4 0.1 1.3 1 Roc Ras of Complex, Roc, domain of DAPkinase 8e-16 58.5 0.1 9.4e-16 58.3 0.1 1.1 1 Arf ADP-ribosylation factor family 5.9e-06 26.9 0.0 9.8e-06 26.2 0.0 1.4 1 MMR_HSR1 50S ribosome-binding GTPase 1e-05 25.9 0.1 0.018 15.3 0.0 2.2 2 RsgA_GTPase RsgA GTPase 2.9e-05 24.2 0.1 0.00017 21.7 0.0 1.9 2 GTP_EFTU Elongation factor Tu GTP binding domain 0.00086 19.3 0.1 0.0011 18.9 0.1 1.3 1 Gtr1_RagA Gtr1/RagA G protein conserved region 0.0013 19.0 0.2 0.38 11.0 0.2 3.1 1 PduV-EutP Ethanolamine utilisation - propanediol utili 0.0031 17.8 0.7 0.22 11.7 0.1 2.8 3 ATP_bind_1 Conserved hypothetical ATP binding protein ------ inclusion threshold ------ 0.02 15.4 0.1 1.6 9.3 0.0 2.3 2 EFhand_Ca_insen Ca2+ insensitive EF hand 0.032 15.2 0.1 0.13 13.2 0.1 1.6 1 AAA_16 AAA ATPase domain 0.056 13.5 0.2 0.28 11.2 0.0 2.1 3 AAA_7 P-loop containing dynein motor region 0.057 13.6 0.0 0.13 12.4 0.0 1.6 1 AAA_24 AAA domain 0.069 12.9 0.0 0.13 12.0 0.0 1.5 1 Septin Septin 0.1 12.6 0.0 11 6.0 0.0 2.2 2 FeoB_N Ferrous iron transport protein B 0.13 11.6 0.5 0.77 9.0 0.2 2.2 2 DLIC Dynein light intermediate chain (DLIC) 0.15 12.8 0.1 0.57 11.0 0.0 2.0 2 AAA_22 AAA domain 0.19 12.7 0.1 4.9 8.1 0.0 2.3 2 AAA ATPase family associated with various cellul Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 171.3 0.1 1.2e-53 1.6e-50 1 161 [. 13 176 .. 13 177 .. 0.96 Alignments for each domain: == domain 1 score: 171.3 bits; conditional E-value: 1.2e-53 Ras 1 klvlvGdsgvGKsslllrfvk..nkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrgaegillvyditseesfenvkkwl 94 k++++G+s+vGK+sl+ ++ k ++F+ + +T g+df + ++vdg +v++qiwDTAGqerfr+l+++ +rg++gillvydit+++sf++++ wl FUN_001904-T1 13 KVLVIGESAVGKTSLIKSYSKpdETFTPSLMPTYGIDFVNIITRVDGVSVRMQIWDTAGQERFRTLTSMHFRGTKGILLVYDITNAHSFDQLNYWL 108 89*****************964489*********************************************************************** PP Ras 95 eeikrvaeenvpivlvGnkvDlee.krevsteegeelakelglkfletSAktkenveeafeelvreil 161 + +k++ +++lv+nk+Dl+e k ev++++g+e+a++lg+kf+etSAkt++nv eaf+el+++++ FUN_001904-T1 109 KAMKKHSLMLEEVILVANKCDLDEhKWEVEMHRGREFARQLGFKFFETSAKTRKNVVEAFQELAKNMK 176 *******97789**********984669************************************9985 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 99.4 0.1 1.6e-31 2.2e-28 1 119 [] 13 129 .. 13 129 .. 0.89 Alignments for each domain: == domain 1 score: 99.4 bits; conditional E-value: 1.6e-31 Roc 1 KvvllGdsgvGKtsllkrfve..defdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyreaaaailvfd...srs 91 Kv+++G+s+vGKtsl+k + + ++f+++ +t+g+df++ +t+++g +++++iWDtaGqerfr+l+++++r+ ++++lv+d ++s FUN_001904-T1 13 KVLVIGESAVGKTSLIKSYSKpdETFTPSLMPTYGIDFVNI-ITRVDG-------VSVRMQIWDTAGQERFRTLTSMHFRGTKGILLVYDitnAHS 100 9******************964489*************975.555665.......4699*******************************865558 PP Roc 92 senlkeWlkelkevagk.spvilvgnkiD 119 +++l++Wlk +k+++ + vilv+nk+D FUN_001904-T1 101 FDQLNYWLKAMKKHSLMlEEVILVANKCD 129 89***********9875279********9 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.3 0.1 6.6e-19 9.4e-16 10 173 .. 7 174 .. 1 175 [. 0.82 Alignments for each domain: == domain 1 score: 58.3 bits; conditional E-value: 6.6e-19 Arf 10 lkkkelrilllGLDnaGKtTilkklkleelv.t..tiPTigfn....veeveiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRle 98 ++ ++++l++G + GKt ++k +++ + + t +PT g + + +v +++++wD Gqe+ R l + f+ t++++ v D ++ + ++ FUN_001904-T1 7 DYDISYKVLVIGESAVGKTSLIKSYSKPDETfTpsLMPTYGIDfvniITRVDGVSVRMQIWDTAGQERFRTLTSMHFRGTKGILLVYDITNAHSFD 102 556789******************9775544145589****872222344555799**************************************** PP Arf 99 eakeeLkalleeeelkeaallvlaNKqDlpealseaeikealgleelkkrkleiqkcsavkgeglkeglewlses 173 + + Lka+ +++ + e ++++aNK Dl+e e e+++ e ++ ++ +++sa +++++ e+++ l+++ FUN_001904-T1 103 QLNYWLKAMKKHSLMLE-EVILVANKCDLDEHKWEVEMHRG--REFARQLGFKFFETSAKTRKNVVEAFQELAKN 174 *******9977766555.56667*******98877666665..555679999*******************9987 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 6.9e-09 9.8e-06 1 113 [] 13 127 .. 13 127 .. 0.71 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 6.9e-09 MMR_HSR1 1 rvaivGrpNvGKStLinaltgkkaiv..sdypgtTrdpnegklelkg..kkielvDtpGliegaseeegleraflaieeadlillvvd..aeeglt 90 +v ++G + vGK++Li++ ++ + s +p d + + +++g +++++Dt+G e +++ + + + ++ illv d + ++++ FUN_001904-T1 13 KVLVIGESAVGKTSLIKSYSKPDETFtpSLMPTYGIDFVNIITRVDGvsVRMQIWDTAG-QE----RFR-TLTSMHFRGTKGILLVYDitNAHSFD 102 689******************7544401555555566655555566655779*******.55....332.22222234489*******88546799 PP MMR_HSR1 91 eldeeleellee..ekkpvilvlnk 113 +l+ l+ + ++ ++vilv+nk FUN_001904-T1 103 QLNYWLKAMKKHslMLEEVILVANK 127 9988888887667778889999998 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.0016 2.3 109 128 .. 14 33 .. 8 43 .. 0.83 2 ! 15.3 0.0 1.3e-05 0.018 27 107 .. 90 174 .. 85 178 .. 0.81 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0016 RsgA_GTPase 109 tvllGqSGvGKStLinallp 128 ++++G+S vGK++Li++ + FUN_001904-T1 14 VLVIGESAVGKTSLIKSYSK 33 5689***********99876 PP == domain 2 score: 15.3 bits; conditional E-value: 1.3e-05 RsgA_GTPase 27 vivvslkepefnlrlldrfLvlaeesgi...epvivlnKiDlleeee..eleelkkeyealgyevllvsaktgegleelkellkgk 107 ++v ++ + + ++l+ L +++++ + e+++v nK Dl e++ e+++ ++ +++lg++++ +sakt++++ e ++l+++ FUN_001904-T1 90 LLVYDIT-NAHSFDQLNYWLKAMKKHSLmleEVILVANKCDLDEHKWevEMHRGREFARQLGFKFFETSAKTRKNVVEAFQELAKN 174 5666666.6677778888888888877766689999******999886788899999***************99988877777765 PP >> GTP_EFTU Elongation factor Tu GTP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.57 8e+02 5 21 .. 13 29 .. 11 37 .. 0.88 2 ! 21.7 0.0 1.2e-07 0.00017 65 184 .. 58 173 .. 45 177 .. 0.74 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.57 GTP_EFTU 5 nigiighvDhGKtTltd 21 + +ig GKt+l+ FUN_001904-T1 13 KVLVIGESAVGKTSLIK 29 5889**********985 PP == domain 2 score: 21.7 bits; conditional E-value: 1.2e-07 GTP_EFTU 65 etkkrlinliDtPGhvdFvkevirglaqlDgavlvvdaveGvepqteevlr.larklgvp...iivviNKmDrvdeaelkevveevkeellekvge 156 ++ + ++++ Dt G + F ++ + + g +lv d+++ + ++ ++k+ + +i+v NK+D+ e++ + v +e+ ++ FUN_001904-T1 58 DGVSVRMQIWDTAGQERFRTLTSMHFRGTKGILLVYDITNAHSFDQLNYWLkAMKKHSLMleeVILVANKCDLD-EHKWE-VEMHRGREFARQ--- 148 46678999*******************************997765555555055555554568**********9.44443.333334456332... PP GTP_EFTU 157 kgekevpvvpgSalkgegvkellealve 184 ++++ +Sa++ ++v e ++ l + FUN_001904-T1 149 ---LGFKFFETSAKTRKNVVEAFQELAK 173 ...3577999999999998877766655 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.1 7.8e-07 0.0011 1 130 [. 13 137 .. 13 177 .. 0.75 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 7.8e-07 Gtr1_RagA 1 kvLLmGksksGKsSirsviFsnyspkdtlrlgatidveksevrf.lg..nltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskelee 93 kvL +G+s GK+S+ + +s+ t +l t ++ ++ + ++ + +++wd Gqe+f + + ++ f+ + ++ v D++ + FUN_001904-T1 13 KVLVIGESAVGKTSLIKS-YSKPDETFTPSLMPTYGIDFVNIITrVDgvSVRMQIWDTAGQERFRTLT-----SMHFRGTKGILLVYDIT---NAH 99 89************9984.77777777889**99998877763313312579**********997765.....777**************...455 PP Gtr1_RagA 94 dlarlketlealsevspeakvfvli.hKvDlisedkre 130 ++++l+ l+a++++s ++ +l+ +K+Dl +++ FUN_001904-T1 100 SFDQLNYWLKAMKKHSLMLEEVILVaNKCDLDEHKWEV 137 66666777777777776665444443788875554444 PP >> PduV-EutP Ethanolamine utilisation - propanediol utilisation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.0 0.2 0.00027 0.38 3 24 .. 13 34 .. 11 173 .. 0.56 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00027 PduV-EutP 3 killiGkvgsGKttLtqalkge 24 k+l+iG++++GKt+L ++ ++ FUN_001904-T1 13 KVLVIGESAVGKTSLIKSYSKP 34 7999999999999999887763 PP >> ATP_bind_1 Conserved hypothetical ATP binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.1 0.096 1.4e+02 1 18 [. 16 33 .. 16 40 .. 0.90 2 ? 1.9 0.0 0.16 2.3e+02 150 170 .. 41 61 .. 35 66 .. 0.84 3 ! 11.7 0.1 0.00016 0.22 92 213 .. 63 174 .. 45 184 .. 0.73 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.096 ATP_bind_1 1 vvGpaGsGKttfvgalse 18 v+G ++GKt+++++ s+ FUN_001904-T1 16 VIGESAVGKTSLIKSYSK 33 89***********99875 PP == domain 2 score: 1.9 bits; conditional E-value: 0.16 ATP_bind_1 150 simlrlelPfvvalnkfDllk 170 s m +++++fv++++++D+++ FUN_001904-T1 41 SLMPTYGIDFVNIITRVDGVS 61 678899************988 PP == domain 3 score: 11.7 bits; conditional E-value: 0.00016 ATP_bind_1 92 dyvlfDtPGQielftlseslakiveaLesefalvavvLvDtrrltdptkflsalllalsimlrlelPfvvalnkfDllkelekelewfedvealsl 187 + Dt GQ ++ tl ++ + +++ +++ + D + + + ++ l+ l a++ + +++ nk+Dl +e++ e+e+ e + FUN_001904-T1 63 RMQIWDTAGQERFRTLTSMHF--------RGTKGILLVYDITNAHS-FDQLNYWLKAMKKHSLMLEEVILVANKCDL-DEHKWEVEMHRGREFARQ 148 56789**********999999........9999***9999998887.555566666777666677789*********.667777777777666666 PP ATP_bind_1 188 llekeeskykklaeaiaelleefalv 213 l k + +k ++++e+++e a + FUN_001904-T1 149 LGFKFFETSAKTRKNVVEAFQELAKN 174 55555466666666666666665554 PP >> EFhand_Ca_insen Ca2+ insensitive EF hand # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.057 80 26 47 .. 94 115 .. 82 131 .. 0.85 2 ? 9.3 0.0 0.0012 1.6 3 28 .. 159 184 .. 157 193 .. 0.90 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.057 EFhand_Ca_insen 26 dLrreLtpeqaeycikrMkpys 47 d+ ++ +q++y k+Mk++s FUN_001904-T1 94 DITNAHSFDQLNYWLKAMKKHS 115 77889999************98 PP == domain 2 score: 9.3 bits; conditional E-value: 0.0012 EFhand_Ca_insen 3 dsaeqvleaFralaegKpYvTeedLr 28 ++ +v+eaF++la++ +Y + dL FUN_001904-T1 159 KTRKNVVEAFQELAKNMKYANNADLV 184 78999**************9999985 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.1 9.5e-05 0.13 27 45 .. 14 32 .. 12 38 .. 0.89 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 9.5e-05 AAA_16 27 vlvsGeaGvGKSalvrell 45 vlv+Ge++vGK++l++++ FUN_001904-T1 14 VLVIGESAVGKTSLIKSYS 32 8**************9876 PP >> AAA_7 P-loop containing dynein motor region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.0002 0.28 33 55 .. 11 33 .. 7 46 .. 0.82 2 ? -2.5 0.0 3.1 4.4e+03 16 41 .. 69 94 .. 59 121 .. 0.67 3 ? -1.2 0.0 1.2 1.8e+03 103 114 .. 192 203 .. 147 210 .. 0.69 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0002 AAA_7 33 kkpvLlvGptGtGKtviikdllk 55 +++vL++G++ +GKt++ik++ k FUN_001904-T1 11 SYKVLVIGESAVGKTSLIKSYSK 33 579****************9876 PP == domain 2 score: -2.5 bits; conditional E-value: 3.1 AAA_7 16 tvdtvrysyllelllknkkpvLlvGp 41 t + r+++l++++ + k +Llv + FUN_001904-T1 69 TAGQERFRTLTSMHFRGTKGILLVYD 94 66667777888888888887777754 PP == domain 3 score: -1.2 bits; conditional E-value: 1.2 AAA_7 103 vvFvDDlnmpak 114 v+vDD+ p FUN_001904-T1 192 FVYVDDITRPSY 203 578899888865 PP >> AAA_24 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 9.1e-05 0.13 3 25 .. 12 34 .. 10 38 .. 0.92 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 9.1e-05 AAA_24 3 lkvliyGpsgiGKTtlakslpkp 25 +kvl++G+s +GKT+l+ks++kp FUN_001904-T1 12 YKVLVIGESAVGKTSLIKSYSKP 34 79*****************9876 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 9e-05 0.13 3 70 .. 10 70 .. 8 75 .. 0.68 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 9e-05 Septin 3 ieftlmvvGesglGkstlinslfetdlieerkieeasekikktveikkkkveieedgvklnltvvDtp 70 i++ ++v+Ges++Gk++li+s + d + + + + + t i+ + + dgv +++++ Dt FUN_001904-T1 10 ISYKVLVIGESAVGKTSLIKSYSKPDETFT-----P--SLMPTYGIDFVNIITRVDGVSVRMQIWDTA 70 7789****************9765543332.....2..344455666666666666666666666665 PP >> FeoB_N Ferrous iron transport protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.019 27 2 20 .. 13 31 .. 12 39 .. 0.86 2 ? 6.0 0.0 0.008 11 104 153 .. 117 168 .. 77 171 .. 0.75 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.019 FeoB_N 2 tvalvGnpnvGkttlfnal 20 +v ++G+ vGkt+l+ + FUN_001904-T1 13 KVLVIGESAVGKTSLIKSY 31 7899***********9876 PP == domain 2 score: 6.0 bits; conditional E-value: 0.008 FeoB_N 104 lglpvvlalnmideaekk.gikidl.kkLskkLgvpvvktsarkkegieell 153 + +v+l+ n++d e+k +++++ ++++++Lg++ +tsa++++++ e FUN_001904-T1 117 MLEEVILVANKCDLDEHKwEVEMHRgREFARQLGFKFFETSAKTRKNVVEAF 168 55689999999997665424455433689***************99987755 PP >> DLIC Dynein light intermediate chain (DLIC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 0.2 0.00054 0.77 26 130 .. 12 114 .. 2 122 .. 0.65 2 ? 0.0 0.0 0.29 4.2e+02 229 256 .. 142 169 .. 120 187 .. 0.75 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.00054 DLIC 26 ksvlvlGedgsGkttliaklqGveeekkGrGleyl...yldvkdedrddltrlnvwildGdlyhkgllkfaleaeslkdtlvilvvdlsrPwtile 118 +vlv+Ge++ Gkt+li +e+ + + ++++ r+++w G + l + + ++lv d+++ + ++ FUN_001904-T1 12 YKVLVIGESAVGKTSLIKSYSKPDETFTPSLMPTYgidFVNIITRVDGVSVRMQIWDTAGQERFRTLTSMHFRGT----KGILLVYDITNAHS-FD 102 579**************9888777766555443330112333332223356777777777777777665444333....34777788887754.68 PP DLIC 119 slqkwasvlreh 130 +l+ w + +++h FUN_001904-T1 103 QLNYWLKAMKKH 114 999999888887 PP == domain 2 score: 0.0 bits; conditional E-value: 0.29 DLIC 229 irrfclqyGaallytsvkedknldllyk 256 r f q G ++ ts k kn+ ++ FUN_001904-T1 142 GREFARQLGFKFFETSAKTRKNVVEAFQ 169 4889999999999999999999865555 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.0004 0.57 8 29 .. 14 35 .. 12 130 .. 0.81 2 ? -0.9 0.0 1.8 2.6e+03 49 81 .. 144 174 .. 137 200 .. 0.56 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.0004 AAA_22 8 lvltGesGtGKTtllrrlleql 29 ++++Ges +GKT l++ + + FUN_001904-T1 14 VLVIGESAVGKTSLIKSYSKPD 35 589**************98764 PP == domain 2 score: -0.9 bits; conditional E-value: 1.8 AAA_22 49 dllrellralglelekelskeellaalqealka 81 +++r+l ++ + k +++ +++a+qe++k+ FUN_001904-T1 144 EFARQLGFKFFETSAK--TRKNVVEAFQELAKN 174 5555555555544444..555555555555444 PP >> AAA ATPase family associated with various cellular activities (AAA) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.0034 4.9 1 67 [. 14 96 .. 14 133 .. 0.59 2 ? 2.4 0.0 0.21 2.9e+02 16 51 .. 143 176 .. 141 201 .. 0.64 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0034 AAA 1 lllyGppGtGKTllakavake..l.gae.............fveisgselv.skyvgesekklrelfeeakkkapsvifiDEiD 67 +l++G +GKT+l+k+ k + + + +++g +++ + + ++++++r l ++ + + ++++ +i FUN_001904-T1 14 VLVIGESAVGKTSLIKSYSKPdeTfT-PslmptygidfvniITRVDGVSVRmQIWDTAGQERFRTLTSMHFRGTKGILLVYDIT 96 699*************9988633221.122222222233333455555555333556666666666666666666666666665 PP == domain 2 score: 2.4 bits; conditional E-value: 0.21 AAA 16 kavakelgaefveisgselvskyvgesekklrelfe 51 + a++lg++f+e+s++ v e ++l++ ++ FUN_001904-T1 143 REFARQLGFKFFETSAKTRK--NVVEAFQELAKNMK 176 56799999999999997666..34444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (219 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 919 (0.0359757); expected 510.9 (0.02) Passed bias filter: 642 (0.0251321); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 18 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2142.61 // Query: FUN_001905-T1 [L=204] Description: FUN_001905 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.9e-39 133.3 0.3 9.8e-39 133.0 0.3 1.1 1 Ras Ras family 1.2e-18 67.9 0.0 2.1e-18 67.2 0.0 1.4 1 Roc Ras of Complex, Roc, domain of DAPkinase 5.2e-07 29.8 0.0 6.5e-07 29.5 0.0 1.1 1 Gtr1_RagA Gtr1/RagA G protein conserved region 5.5e-07 30.1 0.1 5e-05 23.7 0.0 2.1 2 RsgA_GTPase RsgA GTPase 3.8e-06 27.5 0.0 6.3e-06 26.8 0.0 1.4 1 MMR_HSR1 50S ribosome-binding GTPase 6.6e-06 26.2 0.0 7.6e-06 26.0 0.0 1.1 1 Arf ADP-ribosylation factor family 0.0013 19.7 0.0 0.0022 19.0 0.0 1.3 1 AAA_16 AAA ATPase domain 0.0053 17.6 0.1 0.042 14.7 0.1 2.5 1 AAA_22 AAA domain ------ inclusion threshold ------ 0.012 16.7 0.2 0.015 16.3 0.2 1.6 1 ABC_tran ABC transporter 0.014 16.4 0.1 0.023 15.7 0.1 1.3 1 CTD11 C-terminal domain 11 of the ABC-three component 0.014 15.2 0.1 0.039 13.7 0.0 1.7 2 Septin Septin 0.029 14.4 0.2 0.21 11.6 0.2 2.0 1 FeoB_N Ferrous iron transport protein B 0.038 14.0 0.1 11 6.0 0.0 2.6 3 NB-ARC NB-ARC domain 0.05 13.4 0.0 0.074 12.8 0.0 1.3 1 AIG1 AIG1 family 0.072 13.4 0.0 0.15 12.3 0.0 1.5 1 AAA_29 P-loop containing region of AAA domain 0.085 12.4 0.0 0.13 11.9 0.0 1.3 1 MCM MCM P-loop domain 0.099 12.7 0.4 0.11 12.6 0.4 1.3 1 nSTAND1 Novel STAND NTPase 1 0.14 12.8 0.2 0.37 11.5 0.2 1.7 1 pXO2-34 Family of unknown function 0.22 11.5 0.0 0.3 11.0 0.0 1.2 1 TniB Bacterial TniB protein Domain annotation for each model (and alignments): >> Ras Ras family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 133.0 0.3 7.3e-42 9.8e-39 1 160 [. 9 169 .. 9 171 .. 0.97 Alignments for each domain: == domain 1 score: 133.0 bits; conditional E-value: 7.3e-42 Ras 1 klvlvGdsgvGKsslllrfvknkFkeeyesTigvdfktktvevdgkevklqiwDTAGqerfralreayyrg.aegillvyditseesfenvkkwle 95 k+vlvG+sgvGKss+l + + F++ y +T + k++t++v + ++lqiwDT G r+++ a++r+ +g+++++d+t+ +++ n+++w++ FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEPFSHVYVQTKEREIKKTTLNVGRQPLELQIWDTPGNPVCRTITAACLREeVQGAVCIFDVTRDDTYYNMQHWVT 104 89******************************************************************986379********************** PP Ras 96 eikrvae.envpivlvGnkvDleekrevsteegeelakelglkfletSAktkenveeafeelvrei 160 ++++a nv++v vGnkvD + +r+v+ e+ge+lak+++ ++++SA+++ nv+ +f++++++i FUN_001905-T1 105 IVNTYAGsGNVKFVFVGNKVDQK-ERTVNIESGEQLAKQYNGIYIDVSARQNFNVHAIFQTIAERI 169 ******9889***********98.6**************************************998 PP >> Roc Ras of Complex, Roc, domain of DAPkinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.2 0.0 1.6e-21 2.1e-18 1 119 [] 9 125 .. 9 125 .. 0.84 Alignments for each domain: == domain 1 score: 67.2 bits; conditional E-value: 1.6e-21 Roc 1 KvvllGdsgvGKtsllkrfvedefdekekstigvdflskeltkikglendkklkkiklniWDtaGqerfrslhplyyr.eaaaailvfd...srss 92 Kvvl+G+sgvGK+s+l+ + + f++ + +t ++++ +l ++ + + ++l+iWDt G+ r+++ +r e ++a+++fd ++++ FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEPFSHVYVQTKEREIKKTTL-NVGR-------QPLELQIWDTPGNPVCRTITAACLReEVQGAVCIFDvtrDDTY 96 9********************************99987665.4432.......5699**************9877776166899999997434466 PP Roc 93 enlkeWlkelkevag..kspvilvgnkiD 119 n+++W++ ++++ag + ++++vgnk+D FUN_001905-T1 97 YNMQHWVTIVNTYAGsgNVKFVFVGNKVD 125 799**********8822457799****98 PP >> Gtr1_RagA Gtr1/RagA G protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 4.9e-10 6.5e-07 1 148 [. 9 151 .. 9 165 .. 0.72 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 4.9e-10 Gtr1_RagA 1 kvLLmGksksGKsSirsviFsnyspkdtlrlgatidveksevrf.lgnltlnlwdlgGqekfldeyltsqkekifsnvevLiyvfDveskeleedl 95 kv+L+G+s+ GKsSi s F + + ++ +++k+++++ + l+l++wd +G + + ++v+ + +fDv+ +++ ++ FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEPFSHVYVQT-KEREIKKTTLNVgRQPLELQIWDTPGNPVCRTI----TAACLREEVQGAVCIFDVTRDDTYYNM 99 89******************88666554443.34456666665525679*********9876655....577888999**********77777777 PP Gtr1_RagA 96 arlketlealsevspeakvfvlihKvDlisedkreevfeerkeeieeeledle 148 +++ +++ + + s ++k+ +KvD+ ++ e+ e+ +++ + d++ FUN_001905-T1 100 QHWVTIV-NTYAGSGNVKFVFVGNKVDQKERTVNIESGEQLAKQYNGIYIDVS 151 7776655.5677788888766679***99888888877777776665555544 PP >> RsgA_GTPase RsgA GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 3.7e-08 5e-05 109 167 .. 10 65 .. 5 69 .. 0.90 2 ? 4.6 0.0 0.028 37 49 108 .. 110 169 .. 80 181 .. 0.83 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 3.7e-08 RsgA_GTPase 109 tvllGqSGvGKStLinallpelelktgeiseklgrGkhTTtavellkleegglviDtPG 167 +vl+G+SGvGKS+++ + +e + +++k ++ k TT +v +le + DtPG FUN_001905-T1 10 VVLVGESGVGKSSILSTYFGE-PFSHVYVQTKEREIKKTTLNVGRQPLE--LQIWDTPG 65 79******************9.67777899999999******9999998..89*****9 PP == domain 2 score: 4.6 bits; conditional E-value: 0.028 RsgA_GTPase 49 aeesgiepvivlnKiDlleeeeeleelkkeyealgyevllvsaktgegleelkellkgkt 108 a + +++ v v nK+D e++ ++e+ ++ +++++ + vsa+++ +++++ + +++++ FUN_001905-T1 110 AGSGNVKFVFVGNKVDQKERTVNIESGEQLAKQYNGIYIDVSARQNFNVHAIFQTIAERI 169 456688999999*****9999989988888888888899999999999999999888876 PP >> MMR_HSR1 50S ribosome-binding GTPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 4.7e-09 6.3e-06 1 84 [. 9 89 .. 9 123 .. 0.61 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 4.7e-09 MMR_HSR1 1 rvaivGrpNvGKStLinaltgk...kaivsdypgtTrdpnegklelkgkkielvDtpGliegaseeegleraflaieeadlillvvd 84 +v++vG + vGKS+++ + +g+ ++ v+ ++ ++++ + + +++++DtpG + + ++ a l+ ee++ ++ ++d FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEpfsHVYVQTKEREIKKTTLN-VGRQPLELQIWDTPGNPV----CRTITAACLR-EEVQGAVCIFD 89 69*******************854334444433333333333.22344669*******432....2345555553.44555555555 PP >> Arf ADP-ribosylation factor family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.0 5.7e-09 7.6e-06 12 143 .. 5 142 .. 1 172 [. 0.83 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 5.7e-09 Arf 12 kkelrilllGLDnaGKtTilkklkleelvt.tiPTigfnveevei....knlkftvwDvGGqeklRplWk.nYfektdavifvvDsadreRleeak 101 kk ++++l+G + GK+ il + e +++ + T ++++ + + l++++wD G+ R + + e++++ + + D++ + +++ FUN_001905-T1 5 KKVAKVVLVGESGVGKSSILSTYFGEPFSHvYVQTKEREIKKTTLnvgrQPLELQIWDTPGNPVCRTITAaCLREEVQGAVCIFDVTRDDTYYNMQ 100 6889********************999988557788888876555445489****************976156689***************99999 PP Arf 102 eeLkalleeeelkeaallvlaNKqDlpealseaeikealgle 143 + ++ + + ++ ++ ++NK D +e + e e+l+ + FUN_001905-T1 101 HWVTIVNTYAGSGNVKFVFVGNKVDQKERTVNIESGEQLAKQ 142 9998888888899*************9998887777777654 PP >> AAA_16 AAA ATPase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.0 1.7e-06 0.0022 27 66 .. 10 54 .. 6 90 .. 0.71 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 1.7e-06 AAA_16 27 vlvsGeaGvGKSalvrellralera..alvlsgkcdelqrg......l 66 v+++Ge+GvGKS+++++++ + ++++++k +e++++ FUN_001905-T1 10 VVLVGESGVGKSSILSTYFG---EPfsHVYVQTKEREIKKTtlnvgrQ 54 89***************994...3355678888888885544444443 PP >> AAA_22 AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.1 3.1e-05 0.042 8 44 .. 10 42 .. 8 191 .. 0.87 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 3.1e-05 AAA_22 8 lvltGesGtGKTtllrrlleqldeeddsvvlvelpss 44 +vl+GesG+GK+ +l ++ + + s v+v+ ++ FUN_001905-T1 10 VVLVGESGVGKSSILSTYFGE----PFSHVYVQTKER 42 68***************9988....566666665555 PP >> ABC_tran ABC transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.3 0.2 1.1e-05 0.015 13 34 .. 9 30 .. 5 177 .. 0.90 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 1.1e-05 xxxxxxxxxxxxxxxxxxxxxx RF ABC_tran 13 vlalvGenGaGKStLlkllagl 34 +++lvGe+G+GKS++l++ g+ FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGE 30 799*************998887 PP >> CTD11 C-terminal domain 11 of the ABC-three component (ABC-3C) systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.1 1.7e-05 0.023 63 118 .. 117 174 .. 113 179 .. 0.84 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.7e-05 CTD11 63 yrtiqdelkelekrkkl.dvdelakqvkamYkklkekkt.dkeeIfneladklskktk 118 ++++ +++++ e+ ++ + ++lakq + +Y +++++++ + ++If+++a+++ ++ FUN_001905-T1 117 FVFVGNKVDQKERTVNIeSGEQLAKQYNGIYIDVSARQNfNVHAIFQTIAERIDNEGG 174 7889999999999666615699************9988779************88764 PP >> Septin Septin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 2.9e-05 0.039 7 62 .. 10 56 .. 7 66 .. 0.71 2 ? -1.8 0.0 1.6 2.1e+03 21 57 .. 106 142 .. 103 177 .. 0.55 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2.9e-05 Septin 7 lmvvGesglGkstlinslfetdlieerkieeasekikktveikkkkveieedgvkl 62 +++vGesg+Gks+++ + f + + +++++e +k+t+++ ++ l FUN_001905-T1 10 VVLVGESGVGKSSILSTYFGEPFSHVYVQTKEREIKKTTLNVGRQ---------PL 56 789*****************9999886555555555555555443.........34 PP == domain 2 score: -1.8 bits; conditional E-value: 1.6 Septin 21 inslfetdlieerkieeasekikktveikkkkveiee 57 +n+ + ++ + ++ +++++tv+i++ +++ ++ FUN_001905-T1 106 VNTYAGSGNVKFVFVGNKVDQKERTVNIESGEQLAKQ 142 5555555555555555556666666666655444333 PP >> FeoB_N Ferrous iron transport protein B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.2 0.00016 0.21 2 154 .. 9 163 .. 8 165 .. 0.57 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00016 FeoB_N 2 tvalvGnpnvGkttlfnaltgakqkvgNwpGvtvekkegklklke..keielvDlPGiYslsalseeekvardflleekpdvvvnvvdat...... 89 +v+lvG+ vGk++++ + g + + + e k+++l++ + e+++ D+PG +++ +l +e+++ v + d t FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEPFSHVYVQTKEREIKKTTLNVGRqpLELQIWDTPGNPVCR------TITAACL-REEVQGAVCIFDVTrddtyy 97 799*****************997555555555666666666655423788999999964433......2333333.44555555555554111111 PP FeoB_N 90 nlernLyLtlqllel.glpvvlalnmideaekkgikidlkkLskkLgvpvvktsarkkegieellk 154 n++ ++++ + ++++v++ n++d+ e++ ++L+k+ + + +sar++ +++++ + FUN_001905-T1 98 NMQHWVTIVNTYAGSgNVKFVFVGNKVDQKERTVNIESGEQLAKQYNGIYIDVSARQNFNVHAIFQ 163 333333333333322136667777777765554444445667777777777777777777766665 PP >> NB-ARC NB-ARC domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.013 18 21 39 .. 10 28 .. 4 43 .. 0.85 2 ? -2.2 0.0 2.7 3.6e+03 48 61 .. 96 109 .. 89 135 .. 0.73 3 ? 6.0 0.0 0.0083 11 43 80 .. 137 175 .. 129 187 .. 0.83 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.013 NB-ARC 21 valvGmgGvGKttLakeif 39 v lvG GvGK+ +++ f FUN_001905-T1 10 VVLVGESGVGKSSILSTYF 28 789*********9988655 PP == domain 2 score: -2.2 bits; conditional E-value: 2.7 NB-ARC 48 rFdvvawvvvsktf 61 +++ +wv++ +t+ FUN_001905-T1 96 YYNMQHWVTIVNTY 109 57778888887776 PP == domain 3 score: 6.0 bits; conditional E-value: 0.0083 NB-ARC 43 sevegrFd.vvawvvvsktfseeelledilkeLgkeedd 80 +++ ++++ +++ v+ ++f+ + ++++i++++ +e + FUN_001905-T1 137 EQLAKQYNgIYIDVSARQNFNVHAIFQTIAERIDNEGGQ 175 6888999988999*******************9766554 PP >> AIG1 AIG1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 5.5e-05 0.074 2 58 .. 9 65 .. 8 87 .. 0.75 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 5.5e-05 AIG1 2 rivLvGktgnGkSaTgNsilgkkaFesklsaqsvtkkcqkesrtwdgkkinViDTPg 58 ++vLvG +g+GkS+ + g+ + +++++ k ++ + ++ ++++ DTPg FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEPFSHVYVQTKEREIKKTTLNVGRQPLELQIWDTPG 65 69************9999999987666555544444444444455667899999998 PP >> AAA_29 P-loop containing region of AAA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.00011 0.15 25 40 .. 9 24 .. 2 28 .. 0.84 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00011 AAA_29 25 atlltGpsGsGKSTll 40 +++l+G+sG+GKS++l FUN_001905-T1 9 KVVLVGESGVGKSSIL 24 4899**********98 PP >> MCM MCM P-loop domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 9.4e-05 0.13 59 110 .. 9 60 .. 5 94 .. 0.82 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 9.4e-05 MCM 59 nvllvgdpgtaKsqlLkyveklapravytsgkgssaagLtaavvrdeetgef 110 +v+lvg++g++Ks +L++ vy++ k t v r++ + ++ FUN_001905-T1 9 KVVLVGESGVGKSSILSTYFGEPFSHVYVQTKEREIKKTTLNVGRQPLELQI 60 79***************99988889999999998888888888888776665 PP >> nSTAND1 Novel STAND NTPase 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.4 7.9e-05 0.11 36 52 .. 10 26 .. 5 158 .. 0.79 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.9e-05 nSTAND1 36 lavvGaSGsGKSSlvrA 52 +++vG SG+GKSS++ FUN_001905-T1 10 VVLVGESGVGKSSILST 26 899***********976 PP >> pXO2-34 Family of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.2 0.00027 0.37 13 53 .. 128 168 .. 115 175 .. 0.84 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00027 pXO2-34 13 ahkvktfdGktllvldnGklidaadrrevnvanlfrkiksv 53 v+ +G++l nG +id r++ nv +f+ i FUN_001905-T1 128 ERTVNIESGEQLAKQYNGIYIDVSARQNFNVHAIFQTIAER 168 55678889****************************99755 PP >> TniB Bacterial TniB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00022 0.3 29 55 .. 1 27 [. 1 57 [. 0.85 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00022 TniB 29 apkkkrmpnlllvGdsnnGKstivekF 55 +p+ k++ +++lvG+s +GKs i++ + FUN_001905-T1 1 MPPPKKVAKVVLVGESGVGKSSILSTY 27 58889999***************9887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (204 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1018 (0.0398512); expected 510.9 (0.02) Passed bias filter: 759 (0.0297123); expected 510.9 (0.02) Passed Vit filter: 99 (0.00387551); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 19 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2048.68 // Query: FUN_001906-T1 [L=792] Description: FUN_001906 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-55 187.3 6.4 3.1e-55 187.3 6.4 3.3 3 DUF4795 Domain of unknown function (DUF4795) ------ inclusion threshold ------ 0.012 16.5 2.0 0.012 16.5 2.0 5.6 6 Snapin_Pallidin Snapin/Pallidin 0.1 13.3 12.0 12 6.7 0.2 5.2 5 DUF948 Bacterial protein of unknown function (DUF94 0.3 12.0 1.3 38 5.2 0.0 3.0 2 CHMI 5-carboxymethyl-2-hydroxymuconate isomerase 0.89 9.8 7.0 6.8 7.0 0.8 3.5 3 TOP_N Neurolysin/Thimet oligopeptidase, N-terminal 1.2 9.9 7.1 0.24 12.1 1.0 2.8 2 DUF1319 Protein of unknown function (DUF1319) Domain annotation for each model (and alignments): >> DUF4795 Domain of unknown function (DUF4795) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.2 0.064 2.7e+02 102 152 .. 9 57 .. 3 87 .. 0.64 2 ? -0.8 2.7 0.28 1.2e+03 93 149 .. 221 279 .. 211 312 .. 0.65 3 ! 187.3 6.4 7.4e-59 3.1e-55 4 208 .] 334 545 .. 331 545 .. 0.91 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.064 DUF4795 102 eklegqEedwkkaleklskevdtKldreeldplkkqleerlkalrkklkeq 152 ++l+ E++++++++ l++ + t d + + lk+++e+ ++l++ ++ FUN_001906-T1 9 KRLQATEDAVERIMAILHEFLGT--DGKAISGLKSDMEDVANELKNLKESL 57 56666666666666666655543..77777777777777766666544333 PP == domain 2 score: -0.8 bits; conditional E-value: 0.28 DUF4795 93 Lneglqellekle...gqEedwkkaleklskevdtKldreeldplkkqleerlkalrkkl 149 L+ + +e++++l + +++ + ++ +++ + +K+ +e+l+ + ++l+e+l+ l++ l FUN_001906-T1 221 LSAKHNEVQKHLAsvvESQQKIAREVSAVEQALPQKVGKEDLN-IPDDLQEQLALLKQGL 279 4444444444444333566666666777777777777777773.5666666666665554 PP == domain 3 score: 187.3 bits; conditional E-value: 7.4e-59 DUF4795 4 qdeelikelqsavlelqaevekl....nettaelieekeqkqkdidaLyeqiekLeekKadkeqvekeldvKADksalaskvsrdqfDaaleeLne 95 +d+ +++++++++elq+++ kl +++ +el+e++++kq++++aLy+++ekL+e+Kadk++v+ e+dvKADk+al+skv+ ++fD+++++L+e FUN_001906-T1 334 IDSGVLDSIRERLNELQNDQGKLvlttDRQYSELLEDLNRKQEHVEALYDYVEKLQENKADKDNVALEMDVKADKAALESKVNVSTFDNSFNMLDE 429 5778899***************72222455689*************************************************************** PP DUF4795 96 glqellekle...gqEedwkkaleklskevdtKldreeldplkkqleerlkalrkklkeqaeaek...edeAAGfrkqLlerfhCiSCDrpvemav 185 gl+e+l+k++ ++E ++k+al++ls+++++K+d + l+ +k++le+r+++++k+ + ++ae+ ++AAGfrk++ rf+CiSC rpve++ FUN_001906-T1 430 GLREALQKMDdymNEEMALKQALKQLSADMSEKMDGQALQAVKNYLEKRIAEVQKSR-SLIAAEAkvdFADAAGFRKPI--RFNCISCSRPVELPL 522 *********988899***************************************763.3333333346789********..9************** PP DUF4795 186 tgpalptlpsaealpssksvrpy 208 g + +lp+a ++ ++s+ py FUN_001906-T1 523 RGSLQAQLPAARGVRTKRSKAPY 545 *******************9997 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.2 0.23 9.9e+02 63 83 .. 35 55 .. 3 58 .. 0.60 2 ? -4.1 0.0 6 2.6e+04 55 64 .. 80 89 .. 75 92 .. 0.43 3 ? 1.8 2.5 0.11 4.9e+02 13 45 .. 223 255 .. 216 275 .. 0.75 4 ? 1.0 0.4 0.19 8.3e+02 31 60 .. 267 297 .. 263 321 .. 0.68 5 ? 16.5 2.0 2.9e-06 0.012 14 69 .. 338 393 .. 335 403 .. 0.87 6 ? 3.8 1.7 0.027 1.2e+02 9 68 .. 425 483 .. 422 490 .. 0.81 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.23 Snapin_Pallidin 63 KLvnikkrmsslnerlqklqk 83 ++ +k +m+ + + l++l++ FUN_001906-T1 35 AISGLKSDMEDVANELKNLKE 55 456677777777777777775 PP == domain 2 score: -4.1 bits; conditional E-value: 6 Snapin_Pallidin 55 pdlkeyakKL 64 + l+e+++KL FUN_001906-T1 80 SSLEEHLNKL 89 2333333333 PP == domain 3 score: 1.8 bits; conditional E-value: 0.11 Snapin_Pallidin 13 pklkeldeklkelrqsQeeLleqidrlaeeLqe 45 k +e++++l+++ +sQ++ + +++ + L + FUN_001906-T1 223 AKHNEVQKHLASVVESQQKIAREVSAVEQALPQ 255 5667999************99999988888865 PP == domain 4 score: 1.0 bits; conditional E-value: 0.19 Snapin_Pallidin 31 eLleqidrlaeeLqeleelqe.evlpdlkey 60 +L+eq+ l++ L+ l+ +q+ ++l+++k+ FUN_001906-T1 267 DLQEQLALLKQGLEFLKTNQDlAALAEIKSM 297 7999999999999988888887666666653 PP == domain 5 score: 16.5 bits; conditional E-value: 2.9e-06 Snapin_Pallidin 14 klkeldeklkelrqsQeeLleqidrlaeeLqeleelqeevlpdlkeyakKLvnikk 69 +l++++e+l+el++ Q +L + dr+ +eL e + ++e ++ l y++KL++ k FUN_001906-T1 338 VLDSIRERLNELQNDQGKLVLTTDRQYSELLEDLNRKQEHVEALYDYVEKLQENKA 393 7999***********************9987655555569***********98765 PP == domain 6 score: 3.8 bits; conditional E-value: 0.027 Snapin_Pallidin 9 ellepklkeldeklkelrqsQeeLleqidrlaeeLqeleelqeevlpdlkeya.kKLvnik 68 ++l l+e +k + ++ +L++ +++l+++++e + q l+ +k+y+ k++++++ FUN_001906-T1 425 NMLDEGLREALQKMDDYMNEEMALKQALKQLSADMSEKMDGQA--LQAVKNYLeKRIAEVQ 483 6777778888888888999999*************97777777..99*****945566555 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.11 4.6e+02 21 59 .. 4 53 .. 2 60 .. 0.51 2 ? 6.0 0.1 0.0046 20 41 83 .. 210 252 .. 203 256 .. 0.85 3 ? 0.3 0.0 0.27 1.1e+03 20 52 .. 290 322 .. 288 325 .. 0.79 4 ? 6.7 0.2 0.0028 12 35 83 .. 339 391 .. 336 394 .. 0.70 5 ? 1.7 0.2 0.1 4.3e+02 29 68 .. 425 464 .. 415 482 .. 0.84 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.11 DUF948 21 llklkktldevnktlekle...........kqldpllkettellaktnel 59 l+k++k l++++ +e++ k + +l+++++++ +++++l FUN_001906-T1 4 LMKINKRLQATEDAVERIMailheflgtdgKAISGLKSDMEDVANELKNL 53 56666666666666666663333444444444444444444444444444 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0046 DUF948 41 qldpllkettellaktnelledvneklekvdpvfeavkdlges 83 ++++ lk++ el ak ne+++ +++ +e+ +++ ++v+ ++++ FUN_001906-T1 210 EMVECLKQISELSAKHNEVQKHLASVVESQQKIAREVSAVEQA 252 7888999999999999999999999999999998888888776 PP == domain 3 score: 0.3 bits; conditional E-value: 0.27 DUF948 20 tllklkktldevnktleklekqldpllkettel 52 +l ++k+++ + ++++e+++++l + ++ +++ FUN_001906-T1 290 ALAEIKSMAISNKEHVEGIKRELAAIARQNKQT 322 577788888888999999999999998887766 PP == domain 4 score: 6.7 bits; conditional E-value: 0.0028 DUF948 35 leklekqldpllkettellaktne....lledvneklekvdpvfeavkdlges 83 l+++ ++l++l ++ +l+ +t++ lled+n+k e+v+ + + v++l e+ FUN_001906-T1 339 LDSIRERLNELQNDQGKLVLTTDRqyseLLEDLNRKQEHVEALYDYVEKLQEN 391 4555555555555555555555544444999*************999998876 PP == domain 5 score: 1.7 bits; conditional E-value: 0.1 DUF948 29 devnktleklekqldpllkettellaktnelledvnekle 68 + + + l++ +++d++++e +l + +++l +d++ek++ FUN_001906-T1 425 NMLDEGLREALQKMDDYMNEEMALKQALKQLSADMSEKMD 464 5566667778899999999999**************9986 PP >> CHMI 5-carboxymethyl-2-hydroxymuconate isomerase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.0089 38 86 123 .. 81 118 .. 72 119 .. 0.89 2 ? 4.2 0.2 0.018 77 74 118 .. 372 416 .. 370 419 .. 0.92 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.0089 CHMI 86 vlkdhlaelfakrylaLsleleeisealsykknnihar 123 l++hl++l++k++laL ++ ++eal++k++ + r FUN_001906-T1 81 SLEEHLNKLVKKDELALYVKWPALEEALNVKRTDLERR 118 6899***************************9988765 PP == domain 2 score: 4.2 bits; conditional E-value: 0.018 CHMI 74 eekkeagealfavlkdhlaelfakrylaLsleleeisealsykkn 118 + k+e +eal++ +++ ++ +k+++aL ++++ ++al+ k n FUN_001906-T1 372 NRKQEHVEALYDYVEKLQENKADKDNVALEMDVKADKAALESKVN 416 579999****************************99999998877 PP >> TOP_N Neurolysin/Thimet oligopeptidase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 0.27 1.1e+03 25 77 .. 81 137 .. 46 147 .. 0.78 2 ? 3.9 0.0 0.014 61 24 68 .. 209 257 .. 187 286 .. 0.80 3 ? 7.0 0.8 0.0016 6.8 2 87 .. 343 427 .. 342 456 .. 0.82 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.27 TOP_N 25 klvePlekltdr....lsvsWgivshLkgvknspeLreayeevqpevvkfslklsqs 77 +l e l+kl+ + l v W ++ vk ++ r+ ++ + +v+++ ++ + s FUN_001906-T1 81 SLEEHLNKLVKKdelaLYVKWPALEEALNVKRTDLERRHKDKTRTNVLNLENETHGS 137 555566666543223377889999999999999999999999999999988887766 PP == domain 2 score: 3.9 bits; conditional E-value: 0.014 TOP_N 24 eklvePlekltdrlsvsWgivshLkgvknspeL..r..eayeevqpevv 68 ++ve l+++++ + +hL +v +s++ r +a+e+ p++v FUN_001906-T1 209 PEMVECLKQISELSAKHNEVQKHLASVVESQQKiaRevSAVEQALPQKV 257 5799********999999999******9998632232235666666665 PP == domain 3 score: 7.0 bits; conditional E-value: 0.0016 TOP_N 2 kqllkeleeeleelekeveptweklvePlekltdrlsvsWgivshLkgvknspeLreayeevqpevvkfslklsqskpiyeafkal 87 ++ l+el+++ +l + ++++++l+e l++ +++++ + v+ L+ k ++ + +v+ ++ + +k++ s ++f+ l FUN_001906-T1 343 RERLNELQNDQGKLVLTTDRQYSELLEDLNRKQEHVEALYDYVEKLQENKADKDNVALEMDVKADKAALESKVNVST-FDNSFNML 427 677999****************************************9988877766666678888888888877663.44555555 PP >> DUF1319 Protein of unknown function (DUF1319) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.6 0.58 2.5e+03 74 106 .. 225 257 .. 214 260 .. 0.74 2 ? 12.1 1.0 5.6e-05 0.24 1 70 [. 383 463 .. 383 495 .. 0.63 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.58 DUF1319 74 kqeveelvveiskqPklieeealrlteelkqkl 106 ++ev++ ++ + + + i +e ++ + l qk+ FUN_001906-T1 225 HNEVQKHLASVVESQQKIAREVSAVEQALPQKV 257 567887777777777777788888888888887 PP == domain 2 score: 12.1 bits; conditional E-value: 5.6e-05 DUF1319 1 dyldlaetvkitkkelahniaviydrvalssrvnlk...n.lkivleknrsl.......ekeikklksslkklrelylenr 70 dy++ ++ k k ++a ++ v +d+ al s+vn+ n + ++ e r+ +e lk+ lk+l+++++e+ FUN_001906-T1 383 DYVEKLQENKADKDNVALEMDVKADKAALESKVNVStfdNsFNMLDEGLREAlqkmddyMNEEMALKQALKQLSADMSEKM 463 6777788999***********************875222236666654333224443332333468888888888888764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (792 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2336 (0.0914465); expected 510.9 (0.02) Passed bias filter: 913 (0.0357408); expected 510.9 (0.02) Passed Vit filter: 77 (0.00301429); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.48u 0.38s 00:00:00.86 Elapsed: 00:00:00.42 # Mc/sec: 7567.74 // Query: FUN_001907-T1 [L=131] Description: FUN_001907 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 901 (0.0352711); expected 510.9 (0.02) Passed bias filter: 651 (0.0254844); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1315.88 // Query: FUN_001908-T1 [L=215] Description: FUN_001908 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-21 75.6 0.0 7e-21 75.2 0.0 1.1 1 Proteasome Proteasome subunit ------ inclusion threshold ------ 0.2 12.3 0.1 0.38 11.3 0.1 1.4 1 CXCR4_N CXCR4 Chemokine receptor N terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.2 0.0 5.5e-25 7e-21 26 187 .. 25 185 .. 21 187 .. 0.93 Alignments for each domain: == domain 1 score: 75.2 bits; conditional E-value: 5.5e-25 Proteasome 26 agskllskdtveKifkiddhigvafaGlaaDartlvdyaraeaqlyr.lrygepisvelvkrvaaklqaytqrsgrrpfgvslliagvdeegkprL 120 +gs ++ v++++ + ++++v+ +G++aD++++ +++++++ l+ g+ +++ + +++++ +++ r+ + + +++ +++g ++g+ +L FUN_001908-T1 25 YGSLARFRK-VSRLMSVRNNTVVGGSGDYADFQYIQSLLERKVIDDAcLNDGHGYTPK--SIFSWLTREMYHRRSKFNPLWNQIVVGGVKDGEIFL 117 667776777.9*****************************999888879999******..999999999999999999999999999999****** PP Proteasome 121 yqidpsGsvieykdavaiGsgsqaaygvlekey..kedltleeavelakkalkealerdklsgknieva 187 ++d +G +e + va+G g++ a+++l++ + ++ ++ +ea e++ ++l+ +++rd+ s +++e+a FUN_001908-T1 118 GCVDKIGVAFEA-PTVATGFGAYLAQPILRDAFekNPSMSRDEAGEVVTSCLRVLFYRDARSLNKYELA 185 ************.8*******************99999**************************99987 PP >> CXCR4_N CXCR4 Chemokine receptor N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 3e-05 0.38 6 20 .. 42 56 .. 39 57 .. 0.92 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 3e-05 CXCR4_N 6 nnteEiGSGDyedyk 20 nnt+ GSGDy d++ FUN_001908-T1 42 NNTVVGGSGDYADFQ 56 999*99*******97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (215 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 433 (0.0169505); expected 510.9 (0.02) Passed bias filter: 415 (0.0162458); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2143.65 // Query: FUN_001909-T1 [L=316] Description: FUN_001909 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-34 119.6 23.5 5.4e-34 118.8 23.5 1.4 1 YL1 YL1 nuclear protein 2e-14 53.5 0.3 5.7e-14 52.0 0.3 1.8 1 YL1_C YL1 nuclear protein C-terminal domain Domain annotation for each model (and alignments): >> YL1 YL1 nuclear protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 118.8 23.5 4.3e-38 5.4e-34 11 239 .] 1 199 [. 1 199 [. 0.75 Alignments for each domain: == domain 1 score: 118.8 bits; conditional E-value: 4.3e-38 xxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF YL1 11 lkkLleqeeeedelel....lfaEeeeDeeFeseeeeedeesDsdfdsseddeeseeeedeeegekelqrqekkkrkkekkrkaqkkkkklkkkaa 102 ++kL+e e+ d++++ +f+Ee De +e+e+ee+d+ D df+ se de +++edee +r++kk+ k ka+ k + k+++ FUN_001909-T1 1 MSKLIEDEQGVDDFYKtafgGFEEESGDEKYETEDEEADV-VDTDFSISETDEVVDDQEDEEP-----KRKRKKQII--KPYKAPTKDVGKPKATN 88 89*************************************9.*********9998333333322.....222222221..33333322222222111 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF YL1 103 kkkkkkidakepkpkkkseraswlpaeedlkptrRkSsRsstvqnkeaveerlkeaeerrkkiqermkkkakkkkkkkeekelTQeerLaeAketE 198 k+ ++ kk++ +++p ++ +RkS+R+ tv+ +a+++r k+++e+ +++ kk+++++ + + ++lTQee+LaeAk+tE FUN_001909-T1 89 KDTEV----------KKRKIFEEEP-----REGVRKSTRALTVERAQATKNRFKQEKEK-----KTLLKKHQPRRFRDM-RRLTQEELLAEAKITE 163 11222..........2222222222.....3346**********************888.....578888888888776.**************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF YL1 199 eeNlksLnryeeqEeekkkeqraklaalkrrklgpvirfiS 239 eeN sL+ y+++E+ kkk++ ++ alk gpvirf+S FUN_001909-T1 164 EENVASLQAYHQLEADKKKTKI-QKVALK----GPVIRFHS 199 ******************9999.666999....******99 PP >> YL1_C YL1 nuclear protein C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.0 0.3 4.5e-18 5.7e-14 1 29 [] 260 288 .. 260 288 .. 0.99 Alignments for each domain: == domain 1 score: 52.0 bits; conditional E-value: 4.5e-18 YL1_C 1 yCdITGlpAkYtDPkTgLpYanveaYkvi 29 yC++TGlpA+Y DP TgLp+an++a+++i FUN_001909-T1 260 YCPVTGLPARYQDPITGLPFANSQAFRYI 288 9**************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (316 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2095 (0.0820121); expected 510.9 (0.02) Passed bias filter: 557 (0.0218047); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 3146.76 // Query: FUN_001910-T1 [L=249] Description: FUN_001910 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-50 171.7 0.6 1.7e-50 171.3 0.6 1.1 1 CTHRC1_C CTHRC1, C-terminal domain 9.2e-09 35.4 29.2 1.5e-08 34.8 29.2 1.2 1 Collagen Collagen triple helix repeat (20 copies) ------ inclusion threshold ------ 0.13 13.2 0.3 0.13 13.2 0.3 1.5 2 DUF7296 Domain of unknown function (DUF7296) Domain annotation for each model (and alignments): >> CTHRC1_C CTHRC1, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 171.3 0.6 2e-54 1.7e-50 2 137 .] 106 241 .. 105 241 .. 0.98 Alignments for each domain: == domain 1 score: 171.3 bits; conditional E-value: 2e-54 CTHRC1_C 2 alsNvkqcaWkslnegkdngkiaecsftkkesdtalkvayqgnlrviaasscckrwfftlngaecsdPapidgvvylssgspeestvnihraatie 97 + sN+kqc++k+l+++kd g+i+ec f+k+++dt l+v+++g l++ ++++cckrw+ft+ng ec+ Pa+idg+vy+ sg ++ ++ r++tie FUN_001910-T1 106 MESNWKQCVYKDLDQEKDIGLIVECFFKKRSNDTGLHVYFNGVLSLYNCNKCCKRWHFTFNGKECDAPAAIDGIVYMRSGASPNAVNELLRVRTIE 201 689***************************************************************************99888************* PP CTHRC1_C 98 GlCegvqaGlvrvglsVGtCagykegdastgwnsvsriiv 137 G Ce ++ G+v+vg++VG+C gy+++da tg+ svsri+v FUN_001910-T1 202 GACETIPSGNVTVGFWVGNCLGYGDADARTGFKSVSRIFV 241 **************************************97 PP >> Collagen Collagen triple helix repeat (20 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.8 29.2 1.7e-12 1.5e-08 9 57 .. 57 105 .. 56 108 .. 0.65 Alignments for each domain: == domain 1 score: 34.8 bits; conditional E-value: 1.7e-12 Collagen 9 pGppGppGkrGepGeaGekGekGpaGekGppGaaGkpGapGekGeaGap 57 +Gp+Gp+G+rG+pG++G++G++G+ G++G+pG++G+pG++G++G++G+p FUN_001910-T1 57 RGPQGPRGHRGSPGSPGKTGQPGKVGPQGSPGPQGRPGPEGPAGPQGPP 105 5677777777777777777777777777777777777777777777665 PP >> DUF7296 Domain of unknown function (DUF7296) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.1 1.7 1.5e+04 56 63 .. 17 24 .. 15 46 .. 0.71 2 ? 13.2 0.3 1.5e-05 0.13 28 80 .. 127 178 .. 111 209 .. 0.76 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 1.7 DUF7296 56 CdCCGeRW 63 C CC ++ FUN_001910-T1 17 CFCCASKV 24 88997764 PP == domain 2 score: 13.2 bits; conditional E-value: 1.5e-05 DUF7296 28 iiEAesaeeAnekaeeiglyfdgss.dtdCdCCGeRWsevwegeegeevpeieg 80 i+E + n+ + +yf+g +C+ C +RW +++g+e + i+g FUN_001910-T1 127 IVECFFKKRSNDTGLH--VYFNGVLsLYNCNKCCKRWHFTFNGKECDAPAAIDG 178 6666666666665544..4****986789**9***********99888878877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (249 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 806 (0.0315522); expected 510.9 (0.02) Passed bias filter: 490 (0.0191818); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2458.10 // Query: FUN_001910-T2 [L=264] Description: FUN_001910 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-50 171.5 0.6 2e-50 171.1 0.6 1.2 1 CTHRC1_C CTHRC1, C-terminal domain 1e-08 35.3 29.2 1.6e-08 34.6 29.2 1.2 1 Collagen Collagen triple helix repeat (20 copies) ------ inclusion threshold ------ 0.15 13.1 0.3 0.15 13.1 0.3 1.5 2 DUF7296 Domain of unknown function (DUF7296) Domain annotation for each model (and alignments): >> CTHRC1_C CTHRC1, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 171.1 0.6 2.4e-54 2e-50 2 137 .] 121 256 .. 120 256 .. 0.98 Alignments for each domain: == domain 1 score: 171.1 bits; conditional E-value: 2.4e-54 CTHRC1_C 2 alsNvkqcaWkslnegkdngkiaecsftkkesdtalkvayqgnlrviaasscckrwfftlngaecsdPapidgvvylssgspeestvnihraatie 97 + sN+kqc++k+l+++kd g+i+ec f+k+++dt l+v+++g l++ ++++cckrw+ft+ng ec+ Pa+idg+vy+ sg ++ ++ r++tie FUN_001910-T2 121 MESNWKQCVYKDLDQEKDIGLIVECFFKKRSNDTGLHVYFNGVLSLYNCNKCCKRWHFTFNGKECDAPAAIDGIVYMRSGASPNAVNELLRVRTIE 216 689***************************************************************************99888************* PP CTHRC1_C 98 GlCegvqaGlvrvglsVGtCagykegdastgwnsvsriiv 137 G Ce ++ G+v+vg++VG+C gy+++da tg+ svsri+v FUN_001910-T2 217 GACETIPSGNVTVGFWVGNCLGYGDADARTGFKSVSRIFV 256 **************************************97 PP >> Collagen Collagen triple helix repeat (20 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.6 29.2 1.9e-12 1.6e-08 9 57 .. 72 120 .. 71 123 .. 0.65 Alignments for each domain: == domain 1 score: 34.6 bits; conditional E-value: 1.9e-12 Collagen 9 pGppGppGkrGepGeaGekGekGpaGekGppGaaGkpGapGekGeaGap 57 +Gp+Gp+G+rG+pG++G++G++G+ G++G+pG++G+pG++G++G++G+p FUN_001910-T2 72 RGPQGPRGHRGSPGSPGKTGQPGKVGPQGSPGPQGRPGPEGPAGPQGPP 120 5667777777777777777777777777777777777777777777665 PP >> DUF7296 Domain of unknown function (DUF7296) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 1.9 1.7e+04 56 63 .. 32 39 .. 30 60 .. 0.72 2 ? 13.1 0.3 1.7e-05 0.15 28 80 .. 142 193 .. 126 224 .. 0.76 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.9 DUF7296 56 CdCCGeRW 63 C CC ++ FUN_001910-T2 32 CFCCASKV 39 88997764 PP == domain 2 score: 13.1 bits; conditional E-value: 1.7e-05 DUF7296 28 iiEAesaeeAnekaeeiglyfdgss.dtdCdCCGeRWsevwegeegeevpeieg 80 i+E + n+ + +yf+g +C+ C +RW +++g+e + i+g FUN_001910-T2 142 IVECFFKKRSNDTGLH--VYFNGVLsLYNCNKCCKRWHFTFNGKECDAPAAIDG 193 6666666666665544..4****986789**9***********99888878877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (264 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 979 (0.0383245); expected 510.9 (0.02) Passed bias filter: 627 (0.0245449); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.35s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2637.26 // Query: FUN_001911-T1 [L=184] Description: FUN_001911 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 16.0 0.3 0.02 15.4 0.3 1.3 1 BLOC1S3 Biogenesis of lysosome-related organe 0.049 14.2 2.3 0.049 14.2 2.3 2.4 2 zf-CCHC Zinc knuckle 0.1 13.1 0.6 3.4 8.2 0.1 2.2 2 BRCA2_TR2 BRCA2 TR2 domain 3.5 8.5 8.4 0.17 12.8 2.0 2.1 2 zf-CCCH_7 Chromatin remodeling factor Mit1 C-te 4.4 8.0 5.9 6.5 7.5 0.2 2.4 2 Lin-28A-like_zf-CCHC_2 Lin-28A-like, second zinc knuckle Domain annotation for each model (and alignments): >> BLOC1S3 Biogenesis of lysosome-related organelles complex 1 subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.3 4e-06 0.02 83 137 .. 40 95 .. 15 102 .. 0.83 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 4e-06 BLOC1S3 83 kqskkgkydtLLhqkLrEsnarLrkdveq.avkqvyqaaskelesvnkqLsksqlv 137 ++++k+++ tLLh +L E++++L+k ++ +++++ ++ +k l++ n+++ + ++v FUN_001911-T1 40 QKEEKIQVATLLHERLIEREQSLEKTFQAaRIAETSKQHTKSLKEENSRVENVDAV 95 3444899*******************985279999999999999999888776665 PP >> zf-CCHC Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.9 0.51 2.6e+03 3 7 .. 108 112 .. 107 113 .. 0.83 2 ? 14.2 2.3 9.6e-06 0.049 2 17 .. 126 141 .. 125 141 .. 0.92 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 0.51 zf-CCHC 3 CynCG 7 C nCG FUN_001911-T1 108 CGNCG 112 889*9 PP == domain 2 score: 14.2 bits; conditional E-value: 9.6e-06 zf-CCHC 2 kCynCGepGHiardCp 17 C++C + H++r C FUN_001911-T1 126 RCHKCRTMNHLSRMCR 141 7**************5 PP >> BRCA2_TR2 BRCA2 TR2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.1 0.00067 3.4 34 67 .. 60 95 .. 58 105 .. 0.77 2 ? 3.0 0.0 0.029 1.5e+02 5 20 .. 125 140 .. 122 144 .. 0.85 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.00067 BRCA2_TR2 34 psvkkaFqPPRslgl..kyeksskekeqnsgqvtpl 67 +s++k+Fq R ++ +++ks ke+++++++v ++ FUN_001911-T1 60 QSLEKTFQAARIAETskQHTKSLKEENSRVENVDAV 95 5899*******8765227899999999999998654 PP == domain 2 score: 3.0 bits; conditional E-value: 0.029 BRCA2_TR2 5 knlKkrkAldfLsriP 20 +++ k + +++Lsr+ FUN_001911-T1 125 RRCHKCRTMNHLSRMC 140 789**********985 PP >> zf-CCCH_7 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 2.0 3.3e-05 0.17 71 85 .. 107 121 .. 100 124 .. 0.88 2 ? -1.7 0.5 1.1 5.4e+03 70 84 .. 125 140 .. 122 141 .. 0.70 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3.3e-05 zf-CCCH_7 71 rCrcCgieHvPgrCp 85 C Cgi+HvP+ Cp FUN_001911-T1 107 PCGNCGIRHVPASCP 121 5999**********9 PP == domain 2 score: -1.7 bits; conditional E-value: 1.1 zf-CCCH_7 70 vrCrcC.gieHvPgrC 84 rC+ C ++H+ C FUN_001911-T1 125 RRCHKCrTMNHLSRMC 140 5886662689998777 PP >> Lin-28A-like_zf-CCHC_2 Lin-28A-like, second zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 1.3 0.045 2.3e+02 10 18 .. 113 121 .. 108 123 .. 0.85 2 ? 7.5 0.2 0.0013 6.5 3 17 .. 126 140 .. 124 147 .. 0.87 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.045 Lin-28A-like_zf-CCHC_2 10 IsHmVAsCP 18 I H AsCP FUN_001911-T1 113 IRHVPASCP 121 99******* PP == domain 2 score: 7.5 bits; conditional E-value: 0.0013 Lin-28A-like_zf-CCHC_2 3 KCHFCQSIsHmVAsC 17 +CH C ++H+ C FUN_001911-T1 126 RCHKCRTMNHLSRMC 140 8*********86666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1558 (0.0609904); expected 510.9 (0.02) Passed bias filter: 670 (0.0262282); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 1798.85 // Query: FUN_001912-T1 [L=236] Description: FUN_001912 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-39 133.9 1.3 8.8e-39 133.4 1.3 1.2 1 CTHRC1_C CTHRC1, C-terminal domain 9.6e-10 38.6 31.3 1.6e-09 37.9 31.3 1.3 1 Collagen Collagen triple helix repeat (20 copies) Domain annotation for each model (and alignments): >> CTHRC1_C CTHRC1, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 133.4 1.3 6.9e-43 8.8e-39 3 137 .] 104 228 .. 102 228 .. 0.97 Alignments for each domain: == domain 1 score: 133.4 bits; conditional E-value: 6.9e-43 CTHRC1_C 3 lsNvkqcaWkslnegkdngkiaecsftkkesdtalkvayqgnlrviaasscckrwfftlngaecsdPapidgvvylssgspeestvnihraatieG 98 + +kqc++k n++kd+g+i+ec f k+++dt l+v+++g ++++++++cckr +ft+ng ec+ Pa+idg+v++ +g r++tieG FUN_001912-T1 104 ERYWKQCVYKGRNQEKDTGVIVECFFMKRSDDTGLHVYFNGVVSLFKCKKCCKRLHFTFNGKECDAPAAIDGLVFMRRG----------RVRTIEG 189 578**************************************************************************75..........789**** PP CTHRC1_C 99 lCegvqaGlvrvglsVGtCagykegdastgwnsvsriiv 137 Ce ++ G+v+vgl VG+C+g +++ a tg nsvsri+v FUN_001912-T1 190 ACEAIPSGNVTVGLAVGNCNGFSQSKARTGSNSVSRIFV 228 *************************************97 PP >> Collagen Collagen triple helix repeat (20 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.9 31.3 1.2e-13 1.6e-09 7 56 .. 52 101 .. 50 105 .. 0.52 Alignments for each domain: == domain 1 score: 37.9 bits; conditional E-value: 1.2e-13 Collagen 7 GepGppGppGkrGepGeaGekGekGpaGekGppGaaGkpGapGekGeaGa 56 G+pG+pGp+G++G+pG++G +G++G+ G++G+pG++G+pG++G++G++G+ FUN_001912-T1 52 GPPGHPGPKGHPGHPGPPGRPGQPGNVGPQGSPGPQGQPGPEGPAGPPGP 101 55555555555555555555555555555555555555555555555554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (236 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 731 (0.0286162); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 2341.41 // Query: FUN_001913-T1 [L=188] Description: FUN_001913 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-05 26.1 3.1 1.9e-05 25.4 3.1 1.5 1 ENOX1 ENOX1-like domain 0.00016 22.3 3.7 0.086 13.6 0.0 2.3 2 Spc24 Spc24 subunit of Ndc80 0.00033 21.2 1.7 0.00045 20.8 1.7 1.2 1 CENP-F_leu_zip Leucine-rich repeats of kinetochore pro 0.00095 20.0 0.8 1 10.3 0.0 2.5 2 FlaC_arch Flagella accessory protein C (FlaC) 0.0011 19.2 2.6 0.0016 18.7 2.6 1.2 1 SHE3 SWI5-dependent HO expression protein 3 0.0013 19.5 1.9 0.0019 18.9 1.9 1.2 1 DUF4600 Domain of unknown function (DUF4600) 0.0071 16.8 2.3 0.0071 16.8 2.3 2.1 2 bZIP_2 Basic region leucine zipper 0.0091 16.6 2.5 0.14 12.8 0.4 2.5 2 Cep57_CLD_2 Centrosome localisation domain of PPC89 0.0094 16.8 5.0 0.092 13.5 0.2 2.3 2 CC_Bre1 Bre1, coiled-coil containing domain ------ inclusion threshold ------ 0.015 15.6 2.3 1.4 9.2 0.7 2.2 2 NET2A NET2A-like domain 0.016 15.9 3.7 0.016 15.9 3.7 1.4 1 DUF7801 Domain of unknown function (DUF7801) 0.021 14.9 3.1 0.036 14.2 2.5 1.6 1 Kazrin Kazrin domain 0.022 15.3 2.5 0.022 15.3 2.5 2.5 2 bZIP_1 bZIP transcription factor 0.024 15.6 1.8 1.1 10.2 0.1 2.2 2 NPV_P10 Nucleopolyhedrovirus P10 protein 0.027 14.9 0.9 0.14 12.5 0.6 2.0 2 DUF4549 Domain of unknown function (DUF4549) 0.027 15.4 4.5 1.2 10.1 0.1 2.4 2 CLZ C-terminal leucine zipper domain of cyc 0.043 13.7 3.0 0.067 13.0 3.0 1.2 1 GAS Growth-arrest specific micro-tubule bin 0.045 13.5 3.6 2.2 8.0 1.0 2.2 2 DUF3450 Protein of unknown function (DUF3450) 0.074 12.9 0.6 0.12 12.3 0.4 1.4 1 Vps52_C Vps52, C-terminal 0.076 13.2 5.0 0.36 11.0 4.9 1.9 1 Plectin_PPL Periplakin-like, plectin repeat 0.082 14.2 3.2 0.082 14.2 3.2 1.9 1 Rho_Binding Rho Binding 0.1 13.3 2.9 0.17 12.6 2.9 1.3 1 OmpH Outer membrane protein (OmpH-like) 0.11 12.8 3.0 0.45 10.8 3.0 1.8 1 BRE1B BRE1B-like domain 0.11 13.1 3.2 1.9 9.0 2.0 2.2 2 TPR_MLP1_2 TPR/MLP1/MLP2-like protein 0.11 13.0 1.0 0.11 13.0 1.0 1.8 2 EMP24_GP25L emp24/gp25L/p24 family/GOLD 0.11 13.2 2.1 0.52 11.1 2.1 1.9 1 DUF7610 Domain of unknown function (DUF7610) 0.12 13.2 0.1 0.58 11.1 0.1 1.9 2 RS_preATP-grasp-like Ribonucleotide synthetase preATP-grasp 0.15 12.5 2.3 0.85 10.1 1.1 2.2 2 DUF7307 Pam3 gp33-like protein 0.15 11.9 4.9 0.41 10.5 4.9 1.6 1 Tropomyosin Tropomyosin 0.2 12.4 4.0 0.52 11.1 1.3 2.2 2 Rab11-FIP3 Rab11-FIP3-like domain 0.21 12.5 3.4 12 6.9 1.3 2.5 2 DUF4140 N-terminal domain of unknown function ( 0.22 12.0 5.6 0.38 11.2 4.1 1.9 2 Ax_dynein_light Axonemal dynein light chain 0.24 11.4 2.7 0.48 10.5 2.6 1.4 1 FapA Flagellar Assembly Protein A beta solen 0.27 12.3 1.0 4.7 8.3 0.1 2.3 2 DUF7310 Coiled-coil region of unknown function 0.28 12.1 2.3 2.8 8.9 1.2 2.3 2 Snapin_Pallidin Snapin/Pallidin 0.31 11.6 5.8 9.3 6.8 3.4 2.4 2 TMF_DNA_bd TATA element modulatory factor 1 DNA bi 0.39 11.0 4.9 0.46 10.8 2.0 2.2 2 DivIC Septum formation initiator 0.62 11.0 5.7 3.3 8.7 2.0 2.2 2 OVT1 Major antigen, helical domain 0.66 10.6 4.2 5.3 7.7 1.0 2.3 2 XRCC4_CC XRCC4 coiled-coil 0.89 11.2 3.2 14 7.4 1.6 2.5 2 DUF5320 Family of unknown function (DUF5320) 0.97 10.4 7.9 1.3 10.0 2.8 2.7 3 ZapB Cell division protein ZapB 1.1 9.8 6.7 0.64 10.5 3.3 1.9 2 UPF0242 Uncharacterised protein family (UPF0242 1.1 10.0 9.3 3.1 8.5 3.4 2.7 2 HALZ Homeobox associated leucine zipper 1.4 9.4 8.4 3.2 8.2 4.3 2.1 2 Phage_scaffold Phage capsid assembly scaffolding prote 1.8 9.5 7.1 2.9 8.8 3.8 2.1 2 APG6_N Apg6 coiled-coil region Domain annotation for each model (and alignments): >> ENOX1 ENOX1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 3.1 3.3e-08 1.9e-05 2 39 .. 11 48 .. 10 101 .. 0.80 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 3.3e-08 ENOX1 2 eaeaLkeEnDsLrcQLeAyknEvellkqeqkeeleeke 39 +++aL++EnD L QLeA k E e++k+ + e++e++ FUN_001913-T1 11 KVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRT 48 6799************************9998886654 PP >> Spc24 Spc24 subunit of Ndc80 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 2.0 0.0061 3.5 11 44 .. 10 45 .. 5 63 .. 0.79 2 ! 13.6 0.0 0.00015 0.086 10 71 .. 70 148 .. 56 167 .. 0.72 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0061 Spc24 11 kelsdleselerleselaklkeeleeleeeeve..e 44 ++++ l +e ++l+++l++lk+e+e ++++ e e FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAEqmE 45 67889999******************9999999431 PP == domain 2 score: 13.6 bits; conditional E-value: 0.00015 Spc24 10 akelsdleselerleselaklkeeleeleeeeve..................eeselveedetvlklklYrsLGieleed 71 ++ + le+ l r ++ l+ l+++++ +++ + +e+e ++ed++ l lkl++sLG ++ + FUN_001913-T1 70 VQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAIDDifyysyqynlkivgvpqiNENE-SAEDTANLCLKLFSSLGNDISAS 148 55667777788888888888888888888877777777766655555555544444.4559999**********888655 PP >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 1.7 8e-07 0.00045 9 97 .. 9 102 .. 5 128 .. 0.84 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 8e-07 CENP-F_leu_zip 9 lekLKeserkadsLkdkvenLerelemseen.qekvi....leaEnskaevetlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervs 97 +ek K+ + ++d+L+ + e+L++e e ++ + e+++ a k+ v+ l ++ + l ++ + le dL ++++ + L+k+ + ++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKtAEQMEsrtsIVAPPDKQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAID 102 699*********************99766441344441111557789*************************************9887766665 PP >> FlaC_arch Flagella accessory protein C (FlaC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.5 0.014 7.8 15 37 .. 11 33 .. 5 45 .. 0.82 2 ! 10.3 0.0 0.0018 1 4 33 .. 75 104 .. 74 105 .. 0.95 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.014 FlaC_arch 15 eletlrkeneeisksveeieenv 37 ++++lr+en+++ ++e +++++ FUN_001913-T1 11 KVKALRNENDQLNRQLEALKKEF 33 67888999999999999888765 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0018 FlaC_arch 4 elEnklekleseletlrkeneeisksveei 33 +lE++l++++ +l+ l+k+ + i k +++i FUN_001913-T1 75 SLEEDLGRFSRRLDLLEKKFDRIDKAIDDI 104 79*************************987 PP >> SHE3 SWI5-dependent HO expression protein 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 2.6 2.8e-06 0.0016 66 148 .. 10 100 .. 3 117 .. 0.82 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 2.8e-06 SHE3 66 rrvkdlekelseLkesveeltlskkqlkkrlenssasetel.....eeelerlkvqYdalvdsqkeYke...hYqqEieeLkksledlkke 148 +vk l +e+++L+ + e l+ + + +k++ ++ +s t+ +++++ l +Ydalv+s+ e ++++ ++ L+k++++ k FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTSIvappdKQDVQFLSDNYDALVQSKTSLEEdlgRFSRRLDLLEKKFDRIDKA 100 589***********************999998888888876333336899*************9988774446899999999999987765 PP >> DUF4600 Domain of unknown function (DUF4600) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 1.9 3.4e-06 0.0019 16 91 .. 19 98 .. 9 107 .. 0.91 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 3.4e-06 DUF4600 16 NeqLekQisllkeklekir....gnpsdrlasirvyeelsvesLkkllkqlekekrslenqlkdlelrleqeskAyhkvn 91 N+qL++Q++ lk+ e i+ ++ + r + + ++ v+ L+ l + k+sle++l ++ rl+ +k + +++ FUN_001913-T1 19 NDQLNRQLEALKKEFEFIKtktaEQMESRTSIVAPPDKQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRID 98 9*****************987777778889999999***********************************999999886 PP >> bZIP_2 Basic region leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 2.3 1.3e-05 0.0071 31 54 .] 9 32 .. 3 32 .. 0.94 2 ? -0.9 0.0 4.3 2.4e+03 29 44 .. 75 90 .. 56 98 .. 0.56 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.3e-05 bZIP_2 31 eervkeLekeNarLrqkveqleke 54 +e+vk L++eN++L +++e+l+ke FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKE 32 79********************98 PP == domain 2 score: -0.9 bits; conditional E-value: 4.3 bZIP_2 29 eleervkeLekeNarL 44 +lee++ + ++ + L FUN_001913-T1 75 SLEEDLGRFSRRLDLL 90 3444444444444444 PP >> Cep57_CLD_2 Centrosome localisation domain of PPC89 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.4 0.00024 0.14 4 22 .. 11 29 .. 9 40 .. 0.84 2 ? 3.2 0.1 0.23 1.3e+02 3 25 .. 71 93 .. 69 99 .. 0.83 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00024 Cep57_CLD_2 4 enlaLqnrLdsltrklevh 22 ++aL+n++d+l+r+le+ FUN_001913-T1 11 KVKALRNENDQLNRQLEAL 29 6899999999999999875 PP == domain 2 score: 3.2 bits; conditional E-value: 0.23 Cep57_CLD_2 3 aenlaLqnrLdsltrklevhese 25 + +++L+++L +++r+l+ e FUN_001913-T1 71 QSKTSLEEDLGRFSRRLDLLEKK 93 67999***********9988865 PP >> CC_Bre1 Bre1, coiled-coil containing domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 1.0 0.069 39 108 129 .. 11 32 .. 8 49 .. 0.62 2 ! 13.5 0.2 0.00016 0.092 105 139 .. 62 96 .. 55 97 .. 0.90 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.069 CC_Bre1 108 elerlrsekeqleeqletaser 129 +++ lr+e++ql+ qle+++++ FUN_001913-T1 11 KVKALRNENDQLNRQLEALKKE 32 4455555555555555555443 PP == domain 2 score: 13.5 bits; conditional E-value: 0.00016 CC_Bre1 105 lrselerlrsekeqleeqletaserllkaEkklDR 139 l + + l + k +lee+l ++s rl +Ekk+DR FUN_001913-T1 62 LSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDR 96 556789999************************** PP >> NET2A NET2A-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 0.7 0.0024 1.4 153 178 .. 10 35 .. 7 51 .. 0.79 2 ? 5.9 0.0 0.026 15 163 202 .. 60 99 .. 56 107 .. 0.87 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.0024 NET2A 153 alikrLrsetdeLqkqiqsLeedket 178 ++k Lr+e+d+L++q++ L+++ e FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEF 35 5799****************998764 PP == domain 2 score: 5.9 bits; conditional E-value: 0.026 NET2A 163 deLqkqiqsLeedketliedsnklskklkeleeeLkrvqd 202 + L ++ + L + k++l ed +s++l le+++ r+ + FUN_001913-T1 60 QFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRIDK 99 557888899999*************************986 PP >> DUF7801 Domain of unknown function (DUF7801) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 3.7 2.9e-05 0.016 59 148 .. 9 103 .. 4 104 .. 0.83 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.9e-05 DUF7801 59 qkeldeLkaknaeleeelaaLkaekeakeaesae.lqervkaL....ekELretieeyeeltkasielEkeRekleeliDslrdrceqLeaqlsd 148 ++++++L+++n++l+++l+aLk+e e ++++ae +++r++++ +++ + + ++y++l ++ lE + ++ + +D l ++ +++++ + d FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEqMESRTSIVappdKQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAIDD 103 57789999999999999999999988766655441556666665555799999**********************************99988765 PP >> Kazrin Kazrin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 2.5 6.3e-05 0.036 7 66 .. 9 65 .. 5 89 .. 0.69 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 6.3e-05 Kazrin 7 eeeiakLreenerLqaeverlrkeleelkkeaeeeleslesaealsaesaselkvqltql 66 +e+++ Lr+en +L++++e+l+ke e +k++++e++e s++++ a+++++ l++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQME---SRTSIVAPPDKQDVQFLSDN 65 788999********************99888865544...34344444444333334444 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 2.5 3.9e-05 0.022 33 62 .. 10 39 .. 9 41 .. 0.92 2 ? 0.1 0.0 2.2 1.3e+03 30 58 .. 61 89 .. 56 101 .. 0.64 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 3.9e-05 bZIP_1 33 rrvkaLekeNksLkseleelkkevekLksk 62 ++vkaL +eN +L +le lkke e k+k FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTK 39 79*********************9988876 PP == domain 2 score: 0.1 bits; conditional E-value: 2.2 bZIP_1 30 eLerrvkaLekeNksLkseleelkkevek 58 L++ +aL + +sL + l++ + + FUN_001913-T1 61 FLSDNYDALVQSKTSLEEDLGRFSRRLDL 89 56666777777777777777666555443 PP >> NPV_P10 Nucleopolyhedrovirus P10 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.2 0.1 60 27 57 .. 12 39 .. 8 55 .. 0.60 2 ? 10.2 0.1 0.002 1.1 11 61 .. 57 104 .. 54 107 .. 0.92 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.1 NPV_P10 27 vddleenlpdvtelnekLdaqsaqLaelqtk 57 v+ l+++ ++ln +L+a+ ++ + ++tk FUN_001913-T1 12 VKALRNE---NDQLNRQLEALKKEFEFIKTK 39 3333332...235666666666666666664 PP == domain 2 score: 10.2 bits; conditional E-value: 0.002 NPV_P10 11 adikavddkVdalqqqvddleenlpdvtelnekLdaqsaqLaelqtkveeI 61 +d++ ++d dal q+ ++lee+l + +Ld + ++ + +++++++I FUN_001913-T1 57 QDVQFLSDNYDALVQSKTSLEEDLGR---FSRRLDLLEKKFDRIDKAIDDI 104 89********************9999...5699************999998 PP >> DUF4549 Domain of unknown function (DUF4549) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.6 0.00025 0.14 2 50 .. 4 55 .. 3 73 .. 0.81 2 ? 0.9 0.0 0.96 5.4e+02 104 139 .. 60 95 .. 58 98 .. 0.89 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00025 DUF4549 2 ykvssservkeleke...lkkeleelkneieeaelllGkkakslssvsipkd 50 +k+ +e+vk+l++e l+++le+lk+e e + + +++ s +s+ +p d FUN_001913-T1 4 FKMGDKEKVKALRNEndqLNRQLEALKKEFEFIKTKTAEQMESRTSIVAPPD 55 8899999999986543349*********************999999876654 PP == domain 2 score: 0.9 bits; conditional E-value: 0.96 DUF4549 104 qfyldrveqlaqlkylyllrftrfcersdkierlye 139 qf d + l+q k rf +r d +e+ ++ FUN_001913-T1 60 QFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFD 95 8999999*******9999999999999999998775 PP >> CLZ C-terminal leucine zipper domain of cyclic nucleotide-gated channels # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 1.2 0.035 20 30 60 .. 9 39 .. 3 50 .. 0.63 2 ? 10.1 0.1 0.0021 1.2 24 50 .. 71 97 .. 60 103 .. 0.85 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.035 CLZ 30 eekverLessldaLqtrlarLlaelessqkk 60 +ekv+ L ++ d+L+ +l L +e+e + k FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTK 39 4667777777777777777777776644443 PP == domain 2 score: 10.1 bits; conditional E-value: 0.0021 CLZ 24 aeekdleekverLessldaLqtrlarL 50 + + +lee + r+ ++ld L++++ r+ FUN_001913-T1 71 QSKTSLEEDLGRFSRRLDLLEKKFDRI 97 67889********************97 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 3.0 0.00012 0.067 46 132 .. 9 97 .. 5 111 .. 0.87 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00012 GAS 46 ekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslkn..lkarlkelekelkelkwehevleqrfekverErdelyekfeea 132 + +++++++en +l+ +Le++++e e k +++e+ + ++s + k+ ++ l + +++l + + le+ + + +r d l++kf+++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTSIVAppDKQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRI 97 56789999************************99999999998733588888899***************************9999874 PP >> DUF3450 Protein of unknown function (DUF3450) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 1.0 0.0039 2.2 58 98 .. 10 50 .. 8 53 .. 0.82 2 ? 5.9 0.1 0.017 9.9 47 91 .. 60 104 .. 55 112 .. 0.87 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0039 DUF3450 58 aeleslevynkqlerlvasqeqelasleqqieeierierel 98 ++++ l+ +n+ql r+++++++e++ ++++++e + ++ + FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTSI 50 67889999999999999999999999999988766666655 PP == domain 2 score: 5.9 bits; conditional E-value: 0.017 DUF3450 47 qellaeyralkaeleslevynkqlerlvasqeqelasleqqieei 91 q l+++y al + + sle + + +r ++ +e++++++++ i++i FUN_001913-T1 60 QFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAIDDI 104 778899999999999999999999999999999999999999987 PP >> Vps52_C Vps52, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.4 0.00021 0.12 237 291 .. 18 80 .. 12 99 .. 0.80 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00021 Vps52_C 237 keepvarslsrLrndveslllklakkfksr........krqlvfLinNYdlllgvLkelsadl 291 ++++++r+l+ L++++e + +k a +++sr k+ + fL+ NYd l++ l++dl FUN_001913-T1 18 ENDQLNRQLEALKKEFEFIKTKTAEQMESRtsivappdKQDVQFLSDNYDALVQSKTSLEEDL 80 6799*******************99998864444445478899*******9988766666665 PP >> Plectin_PPL Periplakin-like, plectin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 4.9 0.00064 0.36 71 161 .. 9 93 .. 9 97 .. 0.84 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00064 Plectin_PPL 71 reelqeerrerqvleeelealkkelrelekekskveekvvvkEvvkvekDpelekeverLrreieeekrkrrsledeifqlqskiseLere 161 +e+++ +r+e+++l ++lealkke + ++++ ++ e++ + + D ++ v+ L+++++ + + sle+++ + +++ Le++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTK--TA-EQMESRTSIVAPPD---KQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKK 93 5789999*******************99998..44.55555555556777...89999999999999999999999999999999999986 PP >> Rho_Binding Rho Binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 3.2 0.00014 0.082 3 38 .. 10 46 .. 9 51 .. 0.87 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 0.00014 Rho_Binding 3 kdvenlakekeeLnnklkeqeeelekek.eeeeeiek 38 ++v+ l++e+++Ln++l+++++e+e k +++e++e+ FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKtKTAEQMES 46 7899*********************999778888876 PP >> OmpH Outer membrane protein (OmpH-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 2.9 0.00029 0.17 26 107 .. 10 104 .. 7 112 .. 0.65 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00029 OmpH 26 kefkkrqkelekkekelqklqeklq....aeasels..se..keekekelqkkeqelqe.qqqka..qqelqk..kqqellqpilekvkkaikev 107 ++ k++++e ++++++l++l+++++ ++a++++ + ++++q + ++ + q k +++l + ++ +ll++ +++++kai+++ FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEfiktKTAEQMEsrTSivAPPDKQDVQFLSDNYDAlVQSKTslEEDLGRfsRRLDLLEKKFDRIDKAIDDI 104 566777777777777777777777777654444444443366555555566666666664444445589997611555689999********987 PP >> BRE1B BRE1B-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 3.0 0.00078 0.45 18 53 .. 13 48 .. 9 97 .. 0.78 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00078 BRE1B 18 svlynEskqlktqleearkelqtlknehlrqieeme 53 l nE ql++qle ++ke + +k++ +q+e+ FUN_001913-T1 13 KALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRT 48 567889999999999999999999999988888765 PP >> TPR_MLP1_2 TPR/MLP1/MLP2-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 2.0 0.0033 1.9 57 93 .. 10 46 .. 6 49 .. 0.87 2 ? 3.0 0.0 0.25 1.4e+02 86 115 .. 68 97 .. 61 103 .. 0.80 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0033 TPR_MLP1_2 57 kelqalreelnelkaeiaelkaeaesakaeleesees 93 ++++alr+e ++l+ +++ lk+e e k++ +e+ es FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMES 46 67899999999999******99999999999888776 PP == domain 2 score: 3.0 bits; conditional E-value: 0.25 TPR_MLP1_2 86 eleeseesweeqkeelekelselekriedl 115 +l +s+ s+ee ++ ++l+ lek+ + + FUN_001913-T1 68 ALVQSKTSLEEDLGRFSRRLDLLEKKFDRI 97 678889999999999999999999888765 PP >> EMP24_GP25L emp24/gp25L/p24 family/GOLD # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 1.0 0.00019 0.11 109 146 .. 8 45 .. 4 51 .. 0.90 2 ? -0.7 0.0 3 1.7e+03 110 130 .. 84 104 .. 55 114 .. 0.57 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00019 EMP24_GP25L 109 kkekldpleeelkkleeqlneikreqkylrerearhre 146 +kek++ l +e ++l++ql+++k+e+++++++ a+++e FUN_001913-T1 8 DKEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQME 45 79******************************999876 PP == domain 2 score: -0.7 bits; conditional E-value: 3 EMP24_GP25L 110 kekldpleeelkkleeqlnei 130 + ld le++ +++++ +++i FUN_001913-T1 84 SRRLDLLEKKFDRIDKAIDDI 104 334444555555555555554 PP >> DUF7610 Domain of unknown function (DUF7610) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 2.1 0.00092 0.52 1 77 [. 22 98 .. 10 100 .. 0.74 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00092 DUF7610 1 LqkKLeeLeseLeellslppetppsheslse.eieqrfdFlknLLsaEiaShpsskpehLahiaeRLaeLeaaFrewd 77 L++ Le L+ e+e + + +e+ +s++s+++ +q ++Fl a ++S++ s +e L +++RL+ Le++F++ d FUN_001913-T1 22 LNRQLEALKKEFEFIKTKTAEQMESRTSIVApPDKQDVQFLSDNYDALVQSKT-SLEEDLGRFSRRLDLLEKKFDRID 98 55667777777776666666665555555441456677777777777778887.999*****************9876 PP >> RS_preATP-grasp-like Ribonucleotide synthetase preATP-grasp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 0.001 0.58 57 93 .. 20 56 .. 5 61 .. 0.82 2 ? -0.6 0.0 4.3 2.4e+03 45 75 .. 69 99 .. 63 104 .. 0.80 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.001 RS_preATP-grasp-like 57 eelaqkvdvvtfefEnvpaealeelakrvpvfPkpka 93 ++l ++ + + efE + ++++e++++r++++ +p++ FUN_001913-T1 20 DQLNRQLEALKKEFEFIKTKTAEQMESRTSIVAPPDK 56 57889999********************777666654 PP == domain 2 score: -0.6 bits; conditional E-value: 4.3 RS_preATP-grasp-like 45 lvegdyddeaaleelaqkvdvvtfefEnvpa 75 lv+++ + e++l ++ ++ d++ f+ +++ FUN_001913-T1 69 LVQSKTSLEEDLGRFSRRLDLLEKKFDRIDK 99 5666666788999999999999999998875 PP >> DUF7307 Pam3 gp33-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 1.1 0.0015 0.85 7 44 .. 10 46 .. 2 53 .. 0.89 2 ? 1.6 0.0 0.65 3.7e+02 6 35 .. 70 99 .. 56 142 .. 0.65 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.0015 DUF7307 7 drlkelkeeikeleeelkelneeldelrkellpelMee 44 +++k l++e ++l +l++l++e++ ++++ +e+Me+ FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTK-TAEQMES 46 4689**************************.9999997 PP == domain 2 score: 1.6 bits; conditional E-value: 0.65 DUF7307 6 adrlkelkeeikeleeelkelneeldelrk 35 +++ ++l+e+ + +l+ l++++d+++k FUN_001913-T1 70 VQSKTSLEEDLGRFSRRLDLLEKKFDRIDK 99 333334444444444444444444444444 PP >> Tropomyosin Tropomyosin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 4.9 0.00072 0.41 40 139 .. 9 98 .. 5 105 .. 0.64 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00072 Tropomyosin 40 eqevasLtrriqllEeelekleerlkeakekleeaekaadeserarKvlEnrelkddekleelEaqlkeakeiaeeadrkyeEvarklqlleeeLe 135 ++ v++L++ +++l+ +le l+++ + k+k e + +++ d + +++l +++++ + + + ++ + ++r+l lle+ ++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTSIVA---------PPDKQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFD 95 45677777777777777777777777666655554444444444.........4666667777777777777777777777777777777777777 PP Tropomyosin 136 eaee 139 + + FUN_001913-T1 96 RI-D 98 66.3 PP >> Rab11-FIP3 Rab11-FIP3-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 1.3 0.00092 0.52 61 93 .. 10 42 .. 7 52 .. 0.82 2 ? 1.7 0.1 0.74 4.2e+02 76 106 .. 58 88 .. 55 104 .. 0.67 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00092 Rab11-FIP3 61 aRlqqleeEnseLrsevprlkaqlerleeekqk 93 +++++l++En +L+ +++ lk++ e ++ + + FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAE 42 79999*****************99999876544 PP == domain 2 score: 1.7 bits; conditional E-value: 0.74 Rab11-FIP3 76 evprlkaqlerleeekqklqdeleelslelk 106 +v+ l ++ + l + k++l+++l +s++l+ FUN_001913-T1 58 DVQFLSDNYDALVQSKTSLEEDLGRFSRRLD 88 5666677777777777777777777777665 PP >> DUF4140 N-terminal domain of unknown function (DUF4140) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 1.3 0.021 12 66 93 .. 10 37 .. 5 42 .. 0.76 2 ? 5.4 0.1 0.064 36 65 95 .. 57 93 .. 36 97 .. 0.68 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.021 DUF4140 66 eelkelreeieeleaelaaledelaale 93 e++k+lr+e ++l+++l+al++e + ++ FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIK 37 3589999999999999999988876665 PP == domain 2 score: 5.4 bits; conditional E-value: 0.064 DUF4140 65 e......eelkelreeieeleaelaaledelaaleaq 95 + + +++l ++ ++le++l + +l+ le++ FUN_001913-T1 57 QdvqflsDNYDALVQSKTSLEEDLGRFSRRLDLLEKK 93 1345663449999999999999999999999999887 PP >> Ax_dynein_light Axonemal dynein light chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 4.1 0.00067 0.38 125 167 .. 9 51 .. 4 75 .. 0.79 2 ? 0.7 0.0 1.1 6.3e+02 127 157 .. 65 95 .. 54 105 .. 0.55 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00067 Ax_dynein_light 125 ekkikeLeeekeeLekevaelkakleelekreeeerqeeekkh 167 ++k+k+L++e+++L+++++ lk++ e ++++ +e+++++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTSIV 51 5789*******************************99887653 PP == domain 2 score: 0.7 bits; conditional E-value: 1.1 Ax_dynein_light 127 kikeLeeekeeLekevaelkakleelekree 157 + +L + k +Le+ + +++l+ lek++ FUN_001913-T1 65 NYDALVQSKTSLEEDLGRFSRRLDLLEKKFD 95 4445555555555555555555555555443 PP >> FapA Flagellar Assembly Protein A beta solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 2.6 0.00084 0.48 153 227 .. 14 95 .. 4 106 .. 0.50 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00084 FapA 153 elkekleeleeelkeleeeleklkkk..........lkklpkkaekqldeekkeqleklletkekleeeleeleeelkelkeele 227 +l+++ ++l+++l+ l++e e +k k + + p+ kq + ++ ++ l ++k lee+l ++l+ l+++++ FUN_001913-T1 14 ALRNENDQLNRQLEALKKEFEFIKTKtaeqmesrtsIVAPPD---KQDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFD 95 334444555555555555555555553222111222333333...2333445555666666666666666666666666666555 PP >> DUF7310 Coiled-coil region of unknown function (DUF7310) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.1 0.57 3.2e+02 17 45 .. 10 39 .. 5 51 .. 0.57 2 ? 8.3 0.1 0.0082 4.7 22 54 .. 70 102 .. 55 105 .. 0.72 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.57 DUF7310 17 aevdela.daaalaerlealeerldeleer 45 ++v++l+ ++++l+++leal+++ + ++++ FUN_001913-T1 10 EKVKALRnENDQLNRQLEALKKEFEFIKTK 39 345555545556666666666665555555 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0082 DUF7310 22 ladaaalaerlealeerldeleerlaeLeaavq 54 ++++++l+e+l + +rld le++ + ++ a++ FUN_001913-T1 70 VQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAID 102 456778888888888888888888887776655 PP >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 1.2 0.005 2.8 19 54 .. 9 44 .. 8 51 .. 0.84 2 ? 1.9 0.0 0.76 4.3e+02 23 49 .. 67 93 .. 56 119 .. 0.66 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.005 Snapin_Pallidin 19 deklkelrqsQeeLleqidrlaeeLqeleelqeevl 54 +ek+k+lr++ ++L+ q++ l++e++ ++ + e++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQM 44 689**********************97776666444 PP == domain 2 score: 1.9 bits; conditional E-value: 0.76 Snapin_Pallidin 23 kelrqsQeeLleqidrlaeeLqeleel 49 +l qs + L e++ r +++L+ le+ FUN_001913-T1 67 DALVQSKTSLEEDLGRFSRRLDLLEKK 93 566777777777777777777755544 PP >> TMF_DNA_bd TATA element modulatory factor 1 DNA binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 3.4 0.016 9.3 32 58 .. 9 35 .. 5 49 .. 0.78 2 ? 4.6 0.0 0.081 46 37 66 .. 68 97 .. 61 102 .. 0.85 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.016 TMF_DNA_bd 32 nntikkLrkknkeleksvkelkkklek 58 ++++k Lr +n +l+ +++ lkk+ e FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEF 35 688999999999999999999998774 PP == domain 2 score: 4.6 bits; conditional E-value: 0.081 TMF_DNA_bd 37 kLrkknkeleksvkelkkkleklekeleel 66 L + + le+++ +++++l+ lek+ +++ FUN_001913-T1 68 ALVQSKTSLEEDLGRFSRRLDLLEKKFDRI 97 677888999***************999875 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 2.0 0.00081 0.46 30 58 .. 9 37 .. 8 41 .. 0.86 2 ? 0.4 0.1 1.4 8.1e+02 24 50 .. 57 83 .. 55 108 .. 0.60 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00081 DivIC 30 eaeiaklkaeneeLeaeikdLksdeeyie 58 ++++++l++en++L+ +++ Lk+ e+i FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIK 37 57899999999999999999999999886 PP == domain 2 score: 0.4 bits; conditional E-value: 1.4 DivIC 24 qeiaeleaeiaklkaeneeLeaeikdL 50 q+++ l +++++l + + +Le+++ + FUN_001913-T1 57 QDVQFLSDNYDALVQSKTSLEEDLGRF 83 555555666666666666666655444 PP >> OVT1 Major antigen, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 2.0 0.0057 3.3 42 84 .. 9 51 .. 6 64 .. 0.82 2 ? 3.3 0.1 0.28 1.6e+02 28 60 .. 70 102 .. 64 115 .. 0.84 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0057 OVT1 42 rarldavtseldklqteyesatkntvaieqtvkElkqqrDeis 84 ++++ a+++e d+l+ ++e+++k+ i+++ E + r i+ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTSIV 51 7899999999999999999999999999999888777776665 PP == domain 2 score: 3.3 bits; conditional E-value: 0.28 OVT1 28 eelkrkllkdlenqrarldavtseldklqteye 60 + k++l +dl + rld +++ +d++ + + FUN_001913-T1 70 VQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAID 102 577899999999999999999999999987765 PP >> XRCC4_CC XRCC4 coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 1.0 0.0093 5.3 22 49 .. 9 36 .. 4 48 .. 0.75 2 ? 3.6 0.1 0.18 1e+02 37 64 .. 57 83 .. 55 98 .. 0.72 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0093 XRCC4_CC 22 qaknehLqkEnerLlrdwsdvqerleky 49 + k + L++En++L r+++ +++++e + FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFI 36 56778899*************9999843 PP == domain 2 score: 3.6 bits; conditional E-value: 0.18 XRCC4_CC 37 rdwsdvqerlekyveakEeleadLYkrF 64 +d + ++++ + v++k le+dL rF FUN_001913-T1 57 QDVQFLSDNYDALVQSKTSLEEDLG-RF 83 6778888999999**********93.33 PP >> DUF5320 Family of unknown function (DUF5320) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 1.6 0.025 14 71 97 .. 8 34 .. 2 43 .. 0.82 2 ? 3.1 0.0 0.53 3e+02 72 97 .. 63 88 .. 40 104 .. 0.66 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.025 DUF5320 71 keeekelLkeqaelLeeeLeaikkrLe 97 +e+ ++L+++++ L+++Lea+kk++e FUN_001913-T1 8 DKEKVKALRNENDQLNRQLEALKKEFE 34 677888999999999999999998765 PP == domain 2 score: 3.1 bits; conditional E-value: 0.53 DUF5320 72 eeekelLkeqaelLeeeLeaikkrLe 97 +++ ++L + + Lee L + ++rL+ FUN_001913-T1 63 SDNYDALVQSKTSLEEDLGRFSRRLD 88 55566666666667766666666664 PP >> ZapB Cell division protein ZapB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 2.8 0.0024 1.3 18 51 .. 10 43 .. 9 52 .. 0.61 2 ? 1.8 0.1 0.88 5e+02 32 65 .. 57 90 .. 55 96 .. 0.61 3 ? 0.6 0.1 2.1 1.2e+03 6 20 .. 87 104 .. 85 105 .. 0.64 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.0024 ZapB 18 dtielLkmeveeLkekneelaeeaeeleeenqql 51 +++++L++e+++L ++ e+l++e e ++++ + FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQ 43 4566777777777777777777666666554444 PP == domain 2 score: 1.8 bits; conditional E-value: 0.88 ZapB 32 ekneelaeeaeeleeenqqlkeernawqerlesL 65 ++++ l+++ + l ++ l+e+ +++rl+ L FUN_001913-T1 57 QDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLL 90 5555666666666666666677766666666644 PP == domain 3 score: 0.6 bits; conditional E-value: 2.1 ZapB 6 LeqLEsk...iqaavdti 20 L+ LE+k i++a+d i FUN_001913-T1 87 LDLLEKKfdrIDKAIDDI 104 555665422288999987 PP >> UPF0242 Uncharacterised protein family (UPF0242) N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 3.3 0.0011 0.64 110 150 .. 9 49 .. 5 56 .. 0.91 2 ? 0.2 0.1 1.6 9.2e+02 90 135 .. 57 102 .. 53 111 .. 0.72 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.0011 UPF0242 110 eeeleklkeekeqlklkleqisqdfaefkleseeqlkekql 150 +e+++ l++e++ql+ +le+ +++f+ k + eq++ ++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRTS 49 578899******************************99986 PP == domain 2 score: 0.2 bits; conditional E-value: 1.6 UPF0242 90 eeleelqseeeeleeelsqkeeeleklkeekeqlklkleqisqdfa 135 ++++ l ++ + l + + ee l ++ ++ + l+ k + i + ++ FUN_001913-T1 57 QDVQFLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAID 102 5555566666777777778888888888888888887777776655 PP >> HALZ Homeobox associated leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 3.4 0.0055 3.1 21 40 .. 12 31 .. 9 34 .. 0.83 2 ? 4.3 0.3 0.12 66 17 35 .. 62 80 .. 56 93 .. 0.72 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0055 HALZ 21 fdsLkkenqkLkaElqeLke 40 +L++en++L+ +l+ Lk+ FUN_001913-T1 12 VKALRNENDQLNRQLEALKK 31 56899************997 PP == domain 2 score: 4.3 bits; conditional E-value: 0.12 HALZ 17 LksdfdsLkkenqkLkaEl 35 L+ ++d+L + + +L++ l FUN_001913-T1 62 LSDNYDALVQSKTSLEEDL 80 6667777778888887665 PP >> Phage_scaffold Phage capsid assembly scaffolding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 4.3 0.0056 3.2 33 68 .. 9 44 .. 5 52 .. 0.77 2 ? 2.9 0.1 0.24 1.4e+02 31 65 .. 61 96 .. 51 105 .. 0.79 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0056 Phage_scaffold 33 kakldklkeekkelkkqlkeadkqleelkkkdneel 68 k+k+++l +e+++l++ql++ +k+ e k k e++ FUN_001913-T1 9 KEKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQM 44 788899999999999999999999887777754544 PP == domain 2 score: 2.9 bits; conditional E-value: 0.24 Phage_scaffold 31 vpkakldklkeekkelkkqlkeadkqleelkkk.dn 65 + +d+l + k +l+++l +l+ l+kk d FUN_001913-T1 61 FLSDNYDALVQSKTSLEEDLGRFSRRLDLLEKKfDR 96 567889***************999999999888643 PP >> APG6_N Apg6 coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 3.8 0.0052 2.9 67 105 .. 10 48 .. 6 52 .. 0.87 2 ? 1.5 0.1 0.97 5.5e+02 48 83 .. 66 101 .. 51 106 .. 0.61 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0052 APG6_N 67 eeLeelekekeeldaelealeeelealdeeeeefwreyn 105 e++++l +e+++l+++leal++e e ++ + +e++++++ FUN_001913-T1 10 EKVKALRNENDQLNRQLEALKKEFEFIKTKTAEQMESRT 48 688999999999999999999999999999999888775 PP == domain 2 score: 1.5 bits; conditional E-value: 0.97 APG6_N 48 leelekeleklekeeeelleeLeelekekeeldael 83 ++l ++ +le++ + + L+ lek+ +++d+++ FUN_001913-T1 66 YDALVQSKTSLEEDLGRFSRRLDLLEKKFDRIDKAI 101 445555555566666666666666666666666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1825 (0.0714426); expected 510.9 (0.02) Passed bias filter: 1120 (0.0438442); expected 510.9 (0.02) Passed Vit filter: 190 (0.00743785); expected 25.5 (0.001) Passed Fwd filter: 45 (0.0017616); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 45 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 1832.56 // Query: FUN_001914-T1 [L=233] Description: FUN_001914 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.03 14.9 0.7 0.12 13.0 0.7 2.1 1 DUF8005 Family of unknown function (DUF8005) 0.17 12.3 0.4 0.46 10.9 0.4 1.8 1 LapA_dom Lipopolysaccharide assembly protein A domain Domain annotation for each model (and alignments): >> DUF8005 Family of unknown function (DUF8005) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.7 9.3e-06 0.12 14 66 .. 93 145 .. 81 146 .. 0.90 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 9.3e-06 DUF8005 14 tlLFffWiYGivsFalDlknkiiPgirqylrgrrrlkeeeeeeeEreererqL 66 ++ fWi +al + +i +i + +r+ r+l+++ e+ +E ee er+L FUN_001914-T1 93 DVMIAFWITDYCFMALYVTTAYIKEIMRRRRDARQLERKLEQAKEEEELERKL 145 57778999999999999**********************************98 PP >> LapA_dom Lipopolysaccharide assembly protein A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.4 3.6e-05 0.46 36 62 .. 112 138 .. 104 140 .. 0.80 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 3.6e-05 LapA_dom 36 llsllsylrlrrelrrlkkelkkleke 62 + + ++r+rr +r+l+++l+++++e FUN_001914-T1 112 TAYIKEIMRRRRDARQLERKLEQAKEE 138 45556788***************9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (233 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2137 (0.0836563); expected 510.9 (0.02) Passed bias filter: 648 (0.025367); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2263.82 // Query: FUN_001915-T1 [L=119] Description: FUN_001915 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 372 (0.0145625); expected 510.9 (0.02) Passed bias filter: 350 (0.0137013); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1177.06 // Query: FUN_001916-T1 [L=129] Description: FUN_001916 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.027 15.1 0.2 0.048 14.3 0.2 1.4 1 Integrase_H2C2 Integrase zinc binding domain Domain annotation for each model (and alignments): >> Integrase_H2C2 Integrase zinc binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.2 1.9e-06 0.048 31 48 .. 2 19 .. 1 23 [. 0.90 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.9e-06 Integrase_H2C2 31 rrrywWpgmrkdvkkyvk 48 ++++wWp++++d+++ v+ FUN_001916-T1 2 SSYVWWPNIDSDIEETVR 19 789************998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 572 (0.0223919); expected 510.9 (0.02) Passed bias filter: 469 (0.0183598); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.35s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 1350.97 // Query: FUN_001917-T1 [L=331] Description: FUN_001917 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00029 21.5 0.1 0.17 12.5 0.0 3.0 4 DEDDh_C DNA polymerase III subunit epsilon-like, C-terminal Domain annotation for each model (and alignments): >> DEDDh_C DNA polymerase III subunit epsilon-like, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 0.42 1.1e+04 107 124 .. 104 121 .. 77 137 .. 0.56 2 ! 5.2 0.0 0.0011 29 2 32 .. 155 185 .. 154 199 .. 0.85 3 ? -1.1 0.0 0.095 2.4e+03 128 165 .. 197 232 .. 186 237 .. 0.67 4 ! 12.5 0.0 6.5e-06 0.17 132 186 .. 261 318 .. 240 320 .. 0.78 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.42 DEDDh_C 107 nvvLVghdlsqDikyLkk 124 +v+ ++h+++ i++ ++ FUN_001917-T1 104 RVMRIFHSVKDFIRFTNQ 121 333444444444444333 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0011 DEDDh_C 2 fvaiDvEayerdhslitEvGiaildtrdlkg 32 f+ +D + e d++++t +G+ ++ ++ k+ FUN_001917-T1 155 FLVLDAKMCELDPKKVTQIGWVVFSLENPKS 185 8899******************998877554 PP == domain 3 score: -1.1 bits; conditional E-value: 0.095 DEDDh_C 128 dveklenilevvDtaelfqalekeknkrsLervlaele 165 ++ +++il+ +Dt + fq k+ + +L+++l++l+ FUN_001917-T1 197 VLQGKNDILRELDTDHKFQF--KSIEMPNLNEALTNLQ 232 45667788899999998885..4444456666666665 PP == domain 4 score: 12.5 bits; conditional E-value: 6.5e-06 DEDDh_C 132 lenilevvDtaelfqalekek.nkrsLervlaeleiesk..nLHNAGNDAvyTlqall 186 ++++ e++D +l++al +e+ +++++e+v+++l+i+++ L NA + vy +q + FUN_001917-T1 261 ESEVNETIDIITLYSALFHESrKENRMEEVMRKLDIPYEsfGLENARYNVVYIMQTFR 318 467889*********99876515678**********9883358899999999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (331 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1207 (0.04725); expected 510.9 (0.02) Passed bias filter: 776 (0.0303778); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3251.88 // Query: FUN_001918-T1 [L=107] Description: FUN_001918 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.035 14.8 0.5 0.043 14.5 0.5 1.3 1 MRP-L20 Mitochondrial ribosomal protein subunit L20 0.065 13.2 0.3 0.074 13.0 0.3 1.2 1 Pullul_strch_C Alpha-1,6-glucosidases, pullulanase-type, C-t 0.088 12.8 1.1 0.1 12.6 1.1 1.0 1 Z1 Z1 domain 0.12 12.6 1.6 0.16 12.2 1.6 1.3 1 LUC7 LUC7 N_terminus 0.15 13.1 2.1 0.22 12.6 2.1 1.3 1 DUF2408 Protein of unknown function (DUF2408) Domain annotation for each model (and alignments): >> MRP-L20 Mitochondrial ribosomal protein subunit L20 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.5 8.5e-06 0.043 60 115 .. 16 75 .. 4 100 .. 0.72 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 8.5e-06 MRP-L20 60 ekresqkleelPpilkkkkekekkyhltp..edieeirrLraeDPekwsr..kkLakkFg 115 ++++++ l ++ ++ +++e+ ++ ++++ e+ +ei+rLr+e+P+ + r +++ kF+ FUN_001918-T1 16 AQNNAALLGQISKLVADSEENIRRSSVEAadEQLREIKRLRREEPKSFKRegNEIQYKFN 75 444444477777777788887777777653389**************9882235555555 PP >> Pullul_strch_C Alpha-1,6-glucosidases, pullulanase-type, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.3 1.5e-05 0.074 13 75 .. 16 78 .. 14 101 .. 0.90 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.5e-05 Pullul_strch_C 13 aeknedkwplikplLadpalkpskadiaaasaafqelLriRksspLfrLrtaeevqqrvtFpn 75 a++n + i++l+ad + + +++++aa+++++e+ r+R++ p r+ +e+q + +F+ FUN_001918-T1 16 AQNNAALLGQISKLVADSEENIRRSSVEAADEQLREIKRLRREEPKSFKREGNEIQYKFNFKL 78 6778888899*********************************99887899999999999965 PP >> Z1 Z1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 1.1 2.1e-05 0.1 36 114 .. 16 98 .. 6 103 .. 0.81 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 2.1e-05 Z1 36 kdvqekvaelieelleelkealrknskeekeellkeleelwekepts.....daeeeelsfeevkeelkkalekievkvvnskk 114 ++ +++ +i++l+ + +e++r++s e+ +e l+e+++l ++ep+s ++ + +++f+ + e+l++a +++ev v + k FUN_001918-T1 16 AQNNAALLGQISKLVADSEENIRRSSVEAADEQLREIKRLRREEPKSfkregNEIQYKFNFK-LLETLEEAKSHLEVNAVEKVK 98 456677889***********************************777777654455555555.999999999999999887655 PP >> LUC7 LUC7 N_terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 1.6 3.2e-05 0.16 123 171 .. 17 65 .. 4 103 .. 0.75 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.2e-05 LUC7 123 eqikeleekieklleeaeelgeegeVeeaqklmkkveelkeekeeleke 171 ++ + l +i+kl++++ee ++ Ve a + ++++++l++e + k+ FUN_001918-T1 17 QNNAALLGQISKLVADSEENIRRSSVEAADEQLREIKRLRREEPKSFKR 65 555677789******************************9876544333 PP >> DUF2408 Protein of unknown function (DUF2408) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 2.1 4.3e-05 0.22 18 77 .. 22 81 .. 11 103 .. 0.74 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.3e-05 DUF2408 18 irrsllslatrskkeskkeelkelkkeLkeieskrdeegkfassetkevvekgqavlngL 77 ++ ++++l+++s+++ +++++++ ++L+ei+ r ee k ++e++e++ k + l + FUN_001918-T1 22 LLGQISKLVADSEENIRRSSVEAADEQLREIKRLRREEPKSFKREGNEIQYKFNFKLLET 81 56789999******988****************999976655666666555544333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1259 (0.0492856); expected 510.9 (0.02) Passed bias filter: 641 (0.025093); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1094.25 // Query: FUN_001919-T1 [L=91] Description: FUN_001919 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.085 12.9 0.2 0.085 12.9 0.2 1.7 2 zf_C2H2_10 C2H2 type zinc-finger Domain annotation for each model (and alignments): >> zf_C2H2_10 C2H2 type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.2 3.3e-06 0.085 4 18 .. 14 28 .. 12 29 .. 0.92 2 ? -2.9 0.1 0.28 7.3e+03 6 10 .. 46 50 .. 44 51 .. 0.71 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 3.3e-06 zf_C2H2_10 4 aCPKCqevlPDiDtL 18 CP C +PD+ tL FUN_001919-T1 14 ECPVCHGLAPDLQTL 28 6************99 PP == domain 2 score: -2.9 bits; conditional E-value: 0.28 zf_C2H2_10 6 PKCqe 10 P C+ FUN_001919-T1 46 PPCNQ 50 88985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (91 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 649 (0.0254061); expected 510.9 (0.02) Passed bias filter: 516 (0.0201996); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 912.72 // Query: FUN_001920-T1 [L=139] Description: FUN_001920 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-08 34.5 0.1 4.6e-08 33.6 0.1 1.6 1 TNF TNF(Tumour Necrosis Factor) family ------ inclusion threshold ------ 0.09 12.6 0.0 0.11 12.2 0.0 1.1 1 HgmA_N Homogentisate 1,2-dioxygenase N-terminal Domain annotation for each model (and alignments): >> TNF TNF(Tumour Necrosis Factor) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.6 0.1 3.6e-12 4.6e-08 2 43 .. 55 96 .. 54 138 .. 0.79 Alignments for each domain: == domain 1 score: 33.6 bits; conditional E-value: 3.6e-12 TNF 2 sWessregafllsgvsysngkLvvpeaGlYyvYsqvtFrgee 43 +W+++ ++ l+ g+ y++g+L+vp++G Y +Y+q+++ ++ FUN_001920-T1 55 DWNPNAPNSNLAGGMLYKDGQLIVPQSGQYHIYTQLYYLNNK 96 6999999*******************************9333 PP >> HgmA_N Homogentisate 1,2-dioxygenase N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 8.8e-06 0.11 144 193 .. 72 120 .. 60 132 .. 0.86 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 8.8e-06 HgmA_N 144 adGdllivpqkGeleittelGrlkvepgeiaviprGvrfkvevedeearG 193 dG+ livpq+G+ +i+t+l l+ + ++v +G +v++ + ++ G FUN_001920-T1 72 KDGQ-LIVPQSGQYHIYTQLYYLNNKRVMVVVKHKGKDKSVAMISPPSDG 120 5776.79*****************************99999998777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 442 (0.0173028); expected 510.9 (0.02) Passed bias filter: 412 (0.0161284); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.21u 0.42s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1428.09 // Query: FUN_001921-T1 [L=320] Description: FUN_001921 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-26 93.0 0.0 5.6e-26 92.2 0.0 1.4 1 Trypsin Trypsin 6.5e-24 85.1 0.0 9.2e-24 84.6 0.0 1.2 1 MAM MAM domain, meprin/A5/mu 0.0014 19.8 0.0 0.0073 17.5 0.0 2.0 2 Trypsin_2 Trypsin-like peptidase domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.2 0.0 6.5e-30 5.6e-26 2 99 .. 217 317 .. 216 320 .] 0.96 Alignments for each domain: == domain 1 score: 92.2 bits; conditional E-value: 6.5e-30 Trypsin 2 vggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegseqklkvekvivhpnynsdt.ldnDiallkl 94 vgg++a++g++pwq++l ssg CGG+l++++w++TAaHCv+ assv v+lg++ + ++ g+eq ++v k+i hp yn ++ + +Diallkl FUN_001921-T1 217 VGGTDAKPGDWPWQGMLRTSSGFPYCGGTLVTPEWLVTAAHCVETqpASSVFVRLGAYRRWENVGTEQDFSVIKIIKHPSYNNPKrYSHDIALLKL 312 8*********************999********************99999999*****************************99999********* PP Trypsin 95 kspvt 99 ++p+ FUN_001921-T1 313 DKPAA 317 **975 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.6 0.0 1.1e-27 9.2e-24 1 157 [. 20 168 .. 20 169 .. 0.92 Alignments for each domain: == domain 1 score: 84.6 bits; conditional E-value: 1.1e-27 MAM 1 CdFeegslCgw.tqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvl 92 C+F++g lC+ +q+ +d++dW+++++ s+ tgps d + g+G+y ++e+ss ++g++a L + ++ + +C++F+yhm+g+++g+lrvl FUN_001921-T1 20 CNFDSGGLCQGvSQSRNDKFDWSVRKGMtpSSGTGPSGDIN--GNGYYAYIEASSPrRPGDNALLDFDSDLSNGS-TCISFSYHMNGRDVGELRVL 112 *********95489999999*****99999999******99..************99*********999888888.9******************* PP MAM 93 lreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 ++ + e +s +g++g++W + +t+ +v+fe++rg g +gdia+D++s+ + C FUN_001921-T1 113 VNGNVE------FSSKGSKGSKWIKKMMTIAG-VAAKKVTFEGIRGPGWQGDIAIDEVSI--KGC 168 976655......599*****************.9999**********************9..444 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.3 2.6e+03 45 74 .. 67 99 .. 49 177 .. 0.53 2 ! 17.5 0.0 8.6e-07 0.0073 3 62 .. 244 314 .. 242 319 .. 0.77 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.3 Trypsin_2 45 tvvaadpel..Dlallkv.sedgaglpplplgd 74 + a +p++ D all + s+ ++g +++ ++ FUN_001921-T1 67 YIEASSPRRpgDNALLDFdSDLSNGSTCISFSY 99 444455444455555555433333333333333 PP == domain 2 score: 17.5 bits; conditional E-value: 8.6e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav....vaekvsvaladgreyaatvvaadp........elDlallkvse 62 G +v ++ ++T+aH+v+ + ++ v a+++++ + ++ +++ + +p +D+allk+++ FUN_001921-T1 244 GTLVTPEW-LVTAAHCVETQPASSVfvrlGAYRRWENVGTEQDFSVIKIIKHPsynnpkrySHDIALLKLDK 314 88999998.****************77776666777666666666665555558888898888******933 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (320 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 540 (0.0211392); expected 510.9 (0.02) Passed bias filter: 428 (0.0167547); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 3203.73 // Query: FUN_001921-T2 [L=464] Description: FUN_001921 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-69 232.7 0.1 9.4e-69 232.1 0.1 1.3 1 Trypsin Trypsin 1.4e-23 83.9 0.0 2.1e-23 83.4 0.0 1.2 1 MAM MAM domain, meprin/A5/mu 4.2e-05 24.8 0.0 0.00017 22.8 0.0 1.9 2 Trypsin_2 Trypsin-like peptidase domain ------ inclusion threshold ------ 0.17 12.8 0.0 0.29 12.0 0.0 1.3 1 DUF1986 Domain of unknown function (DUF1986) Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 232.1 0.1 1.5e-72 9.4e-69 2 220 .] 230 457 .. 229 457 .. 0.98 Alignments for each domain: == domain 1 score: 232.1 bits; conditional E-value: 1.5e-72 Trypsin 2 vggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegseqklkvekvivhpnynsdt.ldnDiallkl 94 vgg++a++g++pwq++l ssg CGG+l++++w++TAaHCv+ assv v+lg++ + ++ g+eq ++v k+i hp yn ++ + +Diallkl FUN_001921-T2 230 VGGTDAKPGDWPWQGMLRTSSGFPYCGGTLVTPEWLVTAAHCVETqpASSVFVRLGAYRRWENVGTEQDFSVIKIIKHPSYNNPKrYSHDIALLKL 325 8*********************999********************99999999*****************************99999********* PP Trypsin 95 kspvtlgdavrpiclpaassslavgttclvsGwGntkelg..lsdtlqevnvpvvsreecrsayggkvtdnmicagak.ggkdacqGDSGGPlvcs 187 ++p+ l +v+ +clp++ + +t+c+++Gw + +++g ++d+lq+++vp+ +r++c++ay++++ d+micag + gg d+cqGDSGGP+vc+ FUN_001921-T2 326 DKPAALDRNVALACLPQNVTAPGDNTKCWITGWITRFSSGggTPDKLQQASVPIAGRDRCDKAYPRRIHDSMICAGLDqGGIDSCQGDSGGPMVCE 421 *****************777779************999999*************************************999*************** PP Trypsin 188 dg...eliGivswgkgcasgnkpgvytrvssyadwi 220 +g +l+G++swg+gca ++k gvy++v+ +++wi FUN_001921-T2 422 NGgryYLQGVTSWGYGCAGPGKFGVYAKVKFFLPWI 457 ***********************************9 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.4 0.0 3.3e-27 2.1e-23 1 157 [. 33 181 .. 33 182 .. 0.92 Alignments for each domain: == domain 1 score: 83.4 bits; conditional E-value: 3.3e-27 MAM 1 CdFeegslCgw.tqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvl 92 C+F++g lC+ +q+ +d++dW+++++ s+ tgps d + g+G+y ++e+ss ++g++a L + ++ + +C++F+yhm+g+++g+lrvl FUN_001921-T2 33 CNFDSGGLCQGvSQSRNDKFDWSVRKGMtpSSGTGPSGDIN--GNGYYAYIEASSPrRPGDNALLDFDSDLSNGS-TCISFSYHMNGRDVGELRVL 125 *********95489999999*****99999999******99..************99*********999888888.9******************* PP MAM 93 lreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 ++ + e +s +g++g++W + +t+ +v+fe++rg g +gdia+D++s+ + C FUN_001921-T2 126 VNGNVE------FSSKGSKGSKWIKKMMTIAG-VAAKKVTFEGIRGPGWQGDIAIDEVSI--KGC 181 976655......599*****************.9999**********************9..444 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.78 5e+03 48 74 .. 83 112 .. 64 190 .. 0.53 2 ! 22.8 0.0 2.6e-08 0.00017 3 140 .. 257 423 .. 255 426 .. 0.71 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.78 Trypsin_2 48 aadpel..Dlallkv.sedgaglpplplgd 74 a +p++ D all + s+ ++g +++ ++ FUN_001921-T2 83 ASSPRRpgDNALLDFdSDLSNGSTCISFSY 112 444444444445444333333333333333 PP == domain 2 score: 22.8 bits; conditional E-value: 2.6e-08 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav....vaekvsvaladgreyaatvvaadp........elDlallkv.....sedgaglpplp.....lgd.s 75 G +v ++ ++T+aH+v+ + ++ v a+++++ + ++ +++ + +p +D+allk+ +++ +l++lp +gd + FUN_001921-T2 257 GTLVTPEW-LVTAAHCVETQPASSVfvrlGAYRRWENVGTEQDFSVIKIIKHPsynnpkrySHDIALLKLdkpaaLDRNVALACLPqnvtaPGDnT 351 88999998.****************77776667777777777777665555558899898888*******99998555555555554444444445 PP Trypsin_2 76 aplvggervyavGyplggekleslseGtvsavse...srderddeell.....qtdaslspGsSGgPlfdaeG 140 + + +g +++ ++ +g +++ + ++ +++ ++ + r +++++ q ++ G SGgP + ++G FUN_001921-T2 352 KCWITG-WITRFSSGGGTPDKLQQASVPIAGRDRcdkAYPRRIHDSMIcagldQGGIDSCQGDSGGPMVCENG 423 577888.8888888666666657777777777777765555556666689999555555569****9998665 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 4.6e-05 0.29 1 109 [. 240 353 .. 240 358 .. 0.79 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 4.6e-05 DUF1986 1 wPwladvyl.eGdlicsGvlidkswvlvsesclsdvdlehsyvsvvlGgaktkksv..kgpye..qivrvdafkd..vpksevvllhlkskvsfsr 89 wPw + G +c G l+ +w++ c+ + s v v lG+ + +v + ++ +i + ++++ + ++ ll l+++++ r FUN_001921-T2 240 WPWQGMLRTsSGFPYCGGTLVTPEWLVTAAHCVETQPA--SSVFVRLGAYRRWENVgtEQDFSviKIIKHPSYNNpkRYSHDIALLKLDKPAALDR 333 899988876257789*****************987766..788899*****9999965555552245566677752256789************** PP DUF1986 90 hvlPtfvpesrnenekdakc 109 v +p++ ++kc FUN_001921-T2 334 NVALACLPQNVTAPGDNTKC 353 **999999988777777788 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (464 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 452 (0.0176943); expected 510.9 (0.02) Passed bias filter: 362 (0.0141711); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4659.11 // Query: FUN_001921-T3 [L=270] Description: FUN_001921 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-24 85.6 0.0 5.9e-24 85.2 0.0 1.1 1 MAM MAM domain, meprin/A5/mu 5.2e-13 49.8 0.0 1e-12 48.9 0.0 1.5 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.2 0.0 4.6e-28 5.9e-24 1 157 [. 20 168 .. 20 169 .. 0.92 Alignments for each domain: == domain 1 score: 85.2 bits; conditional E-value: 4.6e-28 MAM 1 CdFeegslCgw.tqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvl 92 C+F++g lC+ +q+ +d++dW+++++ s+ tgps d + g+G+y ++e+ss ++g++a L + ++ + +C++F+yhm+g+++g+lrvl FUN_001921-T3 20 CNFDSGGLCQGvSQSRNDKFDWSVRKGMtpSSGTGPSGDIN--GNGYYAYIEASSPrRPGDNALLDFDSDLSNGS-TCISFSYHMNGRDVGELRVL 112 *********95489999999*****99999999******99..************99*********999888888.9******************* PP MAM 93 lreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 ++ + e +s +g++g++W + +t+ +v+fe++rg g +gdia+D++s+ + C FUN_001921-T3 113 VNGNVE------FSSKGSKGSKWIKKMMTIAG-VAAKKVTFEGIRGPGWQGDIAIDEVSI--KGC 168 976655......599*****************.9999**********************9..444 PP >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.9 0.0 7.9e-17 1e-12 2 47 .. 217 262 .. 216 270 .] 0.90 Alignments for each domain: == domain 1 score: 48.9 bits; conditional E-value: 7.9e-17 Trypsin 2 vggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsna 47 vgg++a++g++pwq++l ssg CGG+l++++w++TAaHCv+ + FUN_001921-T3 217 VGGTDAKPGDWPWQGMLRTSSGFPYCGGTLVTPEWLVTAAHCVETQ 262 8*********************999******************983 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (270 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 385 (0.0150714); expected 510.9 (0.02) Passed bias filter: 274 (0.0107262); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.35s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2697.42 // Query: FUN_001921-T4 [L=283] Description: FUN_001921 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-24 85.4 0.0 6.7e-24 85.0 0.0 1.1 1 MAM MAM domain, meprin/A5/mu 5.7e-13 49.7 0.0 1.1e-12 48.8 0.0 1.5 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.0 0.0 5.3e-28 6.7e-24 1 157 [. 33 181 .. 33 182 .. 0.92 Alignments for each domain: == domain 1 score: 85.0 bits; conditional E-value: 5.3e-28 MAM 1 CdFeegslCgw.tqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvl 92 C+F++g lC+ +q+ +d++dW+++++ s+ tgps d + g+G+y ++e+ss ++g++a L + ++ + +C++F+yhm+g+++g+lrvl FUN_001921-T4 33 CNFDSGGLCQGvSQSRNDKFDWSVRKGMtpSSGTGPSGDIN--GNGYYAYIEASSPrRPGDNALLDFDSDLSNGS-TCISFSYHMNGRDVGELRVL 125 *********95489999999*****99999999******99..************99*********999888888.9******************* PP MAM 93 lreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislsegeC 157 ++ + e +s +g++g++W + +t+ +v+fe++rg g +gdia+D++s+ + C FUN_001921-T4 126 VNGNVE------FSSKGSKGSKWIKKMMTIAG-VAAKKVTFEGIRGPGWQGDIAIDEVSI--KGC 181 976655......599*****************.9999**********************9..444 PP >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.8 0.0 8.5e-17 1.1e-12 2 47 .. 230 275 .. 229 283 .] 0.90 Alignments for each domain: == domain 1 score: 48.8 bits; conditional E-value: 8.5e-17 Trypsin 2 vggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsna 47 vgg++a++g++pwq++l ssg CGG+l++++w++TAaHCv+ + FUN_001921-T4 230 VGGTDAKPGDWPWQGMLRTSSGFPYCGGTLVTPEWLVTAAHCVETQ 275 8*********************999******************983 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (283 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 434 (0.0169896); expected 510.9 (0.02) Passed bias filter: 316 (0.0123703); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2870.61 // Query: FUN_001922-T1 [L=105] Description: FUN_001922 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (105 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 495 (0.0193776); expected 510.9 (0.02) Passed bias filter: 403 (0.0157761); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1066.70 // Query: FUN_001923-T1 [L=181] Description: FUN_001923 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.076 13.7 0.0 0.13 12.9 0.0 1.3 1 RAG1_RNase_H Recombination-activation protein 1 (RAG1) RNase Domain annotation for each model (and alignments): >> RAG1_RNase_H Recombination-activation protein 1 (RAG1) RNase H domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 5e-06 0.13 58 100 .. 135 176 .. 130 180 .. 0.80 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 5e-06 RAG1_RNase_H 58 nselvarpLlealgdendretlkailrpieaerkalkdselei 100 +s ++ p+ a +++re lk +l++i++++k+lk++ l++ FUN_001923-T1 135 QSAKSVYPMAIANC-KENRENLKLVLKDINRQKKILKERGLTV 176 45555666666666.677********************99987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 672 (0.0263065); expected 510.9 (0.02) Passed bias filter: 605 (0.0236837); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1799.26 // Query: FUN_001924-T1 [L=402] Description: FUN_001924 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.017 15.4 1.2 0.14 12.5 0.1 2.5 2 Peptidase_C48 Ulp1 protease family, C-terminal catalytic dom Domain annotation for each model (and alignments): >> Peptidase_C48 Ulp1 protease family, C-terminal catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 0.022 5.5e+02 62 94 .. 178 208 .. 167 211 .. 0.78 2 ? 12.5 0.1 5.3e-06 0.14 2 44 .. 354 395 .. 353 399 .. 0.87 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.022 Peptidase_C48 62 kdfyngvrrwtkkvnkkdlfdvdviyiPinldg 94 + n++ +w++ ++ +++ v ++y+ + + FUN_001924-T1 178 CGWKNKTVTWDEG-EQLWIKVVNHLYTMMFG-K 208 567789999****.588**********9987.4 PP == domain 2 score: 12.5 bits; conditional E-value: 5.3e-06 Peptidase_C48 2 hlndtvidfylkllaerleseesknervhflnsffvskLtkkv 44 lnd +i+f++ + +++++ ++ ++hf++sff +kL+++v FUN_001924-T1 354 ELNDAIIAFFVLYTSNHVS-DKDAIDKCHFFSSFFHTKLSERV 395 69*********99987777.7777899*************776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1088 (0.0425915); expected 510.9 (0.02) Passed bias filter: 645 (0.0252496); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3945.12 // Query: FUN_001925-T1 [L=99] Description: FUN_001925 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-08 35.0 0.0 2e-08 34.8 0.0 1.0 1 Peptidase_C48 Ulp1 protease family, C-terminal catalytic dom ------ inclusion threshold ------ 0.17 12.2 0.0 0.22 11.9 0.0 1.2 1 Peptidase_C39 Peptidase C39 family Domain annotation for each model (and alignments): >> Peptidase_C48 Ulp1 protease family, C-terminal catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.8 0.0 1.5e-12 2e-08 133 208 .. 2 78 .. 1 85 [. 0.82 Alignments for each domain: == domain 1 score: 34.8 bits; conditional E-value: 1.5e-12 Peptidase_C48 133 mlpyLveealkkeqkql..dltpfeikrltkvpqqknsgDCGiyvlkfiellaegvpeessq.ltekdvdslrkklavd 208 ++++L e+ k+ + l d ++ +++ kvpqq+n++DCG+yvl f+ +++++ q l+++ ++ +++ av FUN_001925-T1 2 IRSFLRCEWVAKKRSTLqvDEKSLPLVYP-KVPQQDNGYDCGVYVLLFLTEFLQRKLPVA-QlLSDEVLQWYDQGSAVH 78 56778888777777776668888888888.************************999995.559999999998888865 PP >> Peptidase_C39 Peptidase C39 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 1.7e-05 0.22 4 37 .. 32 65 .. 30 96 .. 0.89 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 1.7e-05 Peptidase_C39 4 ivlqvdekdcGlaalamilkyygsevsleeLrel 37 + +q + +dcG+++l + + +++++++++L + FUN_001925-T1 32 VPQQDNGYDCGVYVLLFLTEFLQRKLPVAQLLSD 65 568999************************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 458 (0.0179291); expected 510.9 (0.02) Passed bias filter: 421 (0.0164807); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1019.18 // Query: FUN_001926-T1 [L=190] Description: FUN_001926 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.014 15.4 0.0 0.018 15.0 0.0 1.1 1 AmiA-like N-acetylmuramoyl-L-alanine amidase-like 0.079 13.6 0.2 0.14 12.8 0.2 1.4 1 GED Dynamin GTPase effector domain Domain annotation for each model (and alignments): >> AmiA-like N-acetylmuramoyl-L-alanine amidase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 1.4e-06 0.018 65 128 .. 37 106 .. 33 141 .. 0.77 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1.4e-06 AmiA-like 65 dgkvsylsRkHffsdWaaneekkllrdvtaeispalitvkkqlnkkadgeeylkglkvieral......k 128 dg +++ls + s+W+ +++ +++rdv+++ +p + v+k+l +k +e+ + +l + ++ + FUN_001926-T1 37 DGYLNWLSVLCRASEWILDSRLSCVRDVGHRRQPMFSRVTKRLSNKVYDEQLFRELLEEQQIItakveaL 106 66666666677789*****************************************999888775544333 PP >> GED Dynamin GTPase effector domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.2 1.1e-05 0.14 43 75 .. 74 106 .. 69 118 .. 0.88 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.1e-05 GED 43 slqkellqkLykkekldeLLkEdeeiaqkRkel 75 + k+l +k+y+++ + eLL+E++ i++k + l FUN_001926-T1 74 RVTKRLSNKVYDEQLFRELLEEQQIITAKVEAL 106 67899*********************9986665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (190 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 985 (0.0385594); expected 510.9 (0.02) Passed bias filter: 697 (0.0272852); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1853.74 // Query: FUN_001927-T1 [L=332] Description: FUN_001927 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00079 20.2 1.4 0.0028 18.5 1.4 2.1 1 zf-C2H2 Zinc finger, C2H2 type ------ inclusion threshold ------ 0.038 14.5 0.1 0.17 12.4 0.0 2.1 2 ROS_MUCR ROS/MUCR transcriptional regulator protein 0.1 13.3 0.1 0.37 11.5 0.1 2.0 1 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding 0.12 13.6 0.5 0.12 13.6 0.5 2.4 2 zf-C2H2_4 C2H2-type zinc finger Domain annotation for each model (and alignments): >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 1.4 4.4e-07 0.0028 2 23 .] 45 67 .. 44 67 .. 0.96 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 4.4e-07 zf-C2H2 2 kCpdCgksFsrksnLkrHlrt.H 23 +C dCgk ++++ ++rH+ t H FUN_001927-T1 45 VCFDCGKQYKTRGGFQRHRTTkH 67 6******************9999 PP >> ROS_MUCR ROS/MUCR transcriptional regulator protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 2.7e-05 0.17 57 85 .. 33 67 .. 16 75 .. 0.70 2 ? -1.2 0.0 0.43 2.7e+03 66 79 .. 152 165 .. 83 173 .. 0.61 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2.7e-05 ROS_MUCR 57 kksi...kedsivcledGkkfKs...LkrhLktah 85 k s+ +++ ivc+ +Gk++K+ +rh +t+h FUN_001927-T1 33 KASVennQPEIIVCFDCGKQYKTrggFQRHRTTKH 67 44442227889***********9444477776666 PP == domain 2 score: -1.2 bits; conditional E-value: 0.43 ROS_MUCR 66 vcledGkkfKsLkr 79 + l+ Gk fK L+r FUN_001927-T1 152 IPLNSGKYFKGLSR 165 56777777777766 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 5.9e-05 0.37 4 24 .. 46 66 .. 43 66 .. 0.94 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 5.9e-05 zf-C2H2_jaz 4 CvlCdKyFksenalqnHlkSK 24 C C K++k+ +q+H ++K FUN_001927-T1 46 CFDCGKQYKTRGGFQRHRTTK 66 9*****************998 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.5 1.9e-05 0.12 2 24 .] 45 67 .. 44 67 .. 0.94 2 ? -1.8 0.2 1.8 1.1e+04 5 20 .. 182 196 .. 178 199 .. 0.48 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.9e-05 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 C Cgk+++++ +++rH + H FUN_001927-T1 45 VCFDCGKQYKTRGGFQRHRTTKH 67 5999***************9998 PP == domain 2 score: -1.8 bits; conditional E-value: 1.8 zf-C2H2_4 5 iCgksFsskkaLrrHl 20 +C++ +sk++ + Hl FUN_001927-T1 182 YCKQLKTSKDT-SLHL 196 56333333333.4465 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1362 (0.0533177); expected 510.9 (0.02) Passed bias filter: 882 (0.0345273); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3252.38 // Query: FUN_001928-T1 [L=99] Description: FUN_001928 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 626 (0.0245058); expected 510.9 (0.02) Passed bias filter: 425 (0.0166373); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1010.25 // Query: FUN_001929-T1 [L=560] Description: FUN_001929 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-18 68.1 0.0 2.4e-18 67.0 0.0 1.5 1 ALOG_dom ALOG domain Domain annotation for each model (and alignments): >> ALOG_dom ALOG domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.0 0.0 9.4e-23 2.4e-18 14 126 .] 309 414 .. 299 414 .. 0.90 Alignments for each domain: == domain 1 score: 67.0 bits; conditional E-value: 9.4e-23 ALOG_dom 14 yesqkrrdwntfvqylknkrPPlelarcsgahvleflryldqfGktkvhaeacvffGqaepaapckcPlrqawGsldaliGrlraafeenggkaes 109 ye++k + +l + P ++l+ + ++++++fl +d Gk k+h ++c + c+cP r+a+G +d+ iG+lr++f++ g+ s FUN_001929-T1 309 YERHKDSLEVQLSSFLFSLVPSKKLSAATAEDIVKFLISKDSAGKRKLHFSSCS-------RKICNCPKRLAAGNVDSYIGKLRSIFNKLGRVGMS 397 5555555555678899*************************************6.......468******************************** PP ALOG_dom 110 nPfaaravrvylrevre 126 nP ++ +++ yl+ vre FUN_001929-T1 398 NPLSHPTIKEYLKFVRE 414 *************9997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (560 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 456 (0.0178509); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.44s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 5455.63 // Query: FUN_001930-T1 [L=329] Description: FUN_001930 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.012 16.0 7.0 0.022 15.2 7.0 1.3 1 Mod_r Modifier of rudimentary (Mod(r)) protein 0.025 15.4 0.2 0.069 14.0 0.2 1.8 1 INO80E INO80 complex subunit E 0.027 14.8 2.3 0.027 14.8 2.3 2.0 2 DivIC Septum formation initiator 0.037 14.7 7.1 0.076 13.7 2.7 3.1 2 HALZ Homeobox associated leucine zipper 0.051 14.1 2.3 0.11 13.1 2.3 1.5 1 Sec10_N Exocyst complex component Sec10, N-terminal 0.068 14.3 6.3 0.16 13.1 6.3 1.6 1 PRKG1_interact cGMP-dependent protein kinase interacting do 0.078 13.3 2.8 0.2 12.0 0.4 2.3 2 SKA2 Spindle and kinetochore-associated protein 2 0.092 11.1 1.7 0.12 10.7 1.7 1.1 1 V_ATPase_I V-type ATPase 116kDa subunit family 0.11 13.4 0.4 0.19 12.6 0.4 1.4 1 Spectrin_SESTD1 SESTD1-like, spectrin repeat 0.22 11.2 5.6 0.32 10.7 5.6 1.2 1 DUF4763 Domain of unknown function (DUF4763) 0.35 10.6 1.1 0.53 10.0 1.1 1.2 1 DUF4407 Domain of unknown function (DUF4407) 0.37 11.2 3.0 0.98 9.8 2.9 1.8 1 WxL WxL domain surface cell wall-binding 0.41 10.6 7.0 0.63 10.0 7.0 1.2 1 HAUS-augmin3 HAUS augmin-like complex subunit 3 0.46 11.1 7.6 0.21 12.1 4.0 1.9 2 ADIP Afadin- and alpha -actinin-Binding 0.52 10.9 4.3 1 10.0 4.3 1.5 1 BBS2_hp BBS2 hairpin 0.87 9.6 5.6 3.4 7.7 5.6 1.9 1 PI3K_P85_iSH2 Phosphatidylinositol 3-kinase regulatory sub 2.1 8.9 6.6 8.4 6.9 6.5 1.9 1 Nup54 Nucleoporin complex subunit 54 2.3 9.0 9.1 0.11 13.3 2.4 2.1 2 Uso1_p115_C Uso1 / p115 like vesicle tethering protein, 2.4 8.2 4.4 1.2 9.2 2.3 1.5 2 FapA Flagellar Assembly Protein A beta solenoid d 2.4 8.9 8.3 5.5 7.8 7.8 1.9 1 CCDC-167 Coiled-coil domain-containing protein 167 5.4 7.7 10.1 0.43 11.2 0.9 2.9 3 bZIP_1 bZIP transcription factor 5.8 8.0 5.8 1.9 9.6 1.6 2.2 2 YabA Initiation control protein YabA Domain annotation for each model (and alignments): >> Mod_r Modifier of rudimentary (Mod(r)) protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 7.0 1.9e-05 0.022 36 107 .. 199 281 .. 184 286 .. 0.81 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.9e-05 Mod_r 36 eellaeneslaeenlekep..........eleelrsqlqekleelkaleeeyeekeqeldell.skfspdallarLqaavaea 107 ++ +++n + +++nl++e+ el lr++ ++ + l le++ye +++e +ll ++ s ++l++L++++++ FUN_001930-T1 199 QKQVEANTRSLSSNLQSEEtiiseelqplELARLRNENRALTQRLSDLENSYESLKREARSLLdENKSLVTALRLLNNEIDKG 281 344455555555566665556666667799************************************************99875 PP >> INO80E INO80 complex subunit E # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.2 5.9e-05 0.069 4 29 .. 248 273 .. 245 280 .. 0.86 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 5.9e-05 INO80E 4 kkYkeLKrklklLiyEnecfqeeLrk 29 + Y++LKr ++L++En ++ +Lr FUN_001930-T1 248 NSYESLKREARSLLDENKSLVTALRL 273 68*****************9999985 PP >> DivIC Septum formation initiator # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 8.2 9.5e+03 29 42 .. 122 135 .. 109 137 .. 0.73 2 ? 14.8 2.3 2.3e-05 0.027 32 65 .. 228 261 .. 222 263 .. 0.93 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 8.2 DivIC 29 leaeiaklkaenee 42 l++++++l ++ne+ FUN_001930-T1 122 LKEQLVNLFQRNEA 135 56666666666665 PP == domain 2 score: 14.8 bits; conditional E-value: 2.3e-05 DivIC 32 eiaklkaeneeLeaeikdLksdeeyieerARkel 65 e+a+l++en++L++++ dL++++e + + AR+ l FUN_001930-T1 228 ELARLRNENRALTQRLSDLENSYESLKREARSLL 261 799****************************765 PP >> HALZ Homeobox associated leucine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.3 0.15 1.8e+02 23 40 .. 231 248 .. 228 249 .. 0.87 2 ? 13.7 2.7 6.6e-05 0.076 10 40 .. 246 276 .. 244 279 .. 0.91 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.15 HALZ 23 sLkkenqkLkaElqeLke 40 L++en++L + l+ L + FUN_001930-T1 231 RLRNENRALTQRLSDLEN 248 599********9999975 PP == domain 2 score: 13.7 bits; conditional E-value: 6.6e-05 HALZ 10 LKasYdsLksdfdsLkkenqkLkaElqeLke 40 L sY+sLk + sL++en++L + l+ L++ FUN_001930-T1 246 LENSYESLKREARSLLDENKSLVTALRLLNN 276 6679*********************999987 PP >> Sec10_N Exocyst complex component Sec10, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 2.3 9.2e-05 0.11 13 77 .. 193 262 .. 182 276 .. 0.79 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 9.2e-05 Sec10_N 13 keLkeLqeqvqekeqklekavrqaeakhskkln.....eLskkldqivdsfqqLdekisevgqkvvelGe 77 eL Lq+qv+++++ l+++++++e s++l+ +L++++ ++++ ++L+++ +++++++ +l++ FUN_001930-T1 193 LELVILQKQVEANTRSLSSNLQSEETIISEELQplelaRLRNENRALTQRLSDLENSYESLKREARSLLD 262 39***************************98762222266788888888888888888888888777765 PP >> PRKG1_interact cGMP-dependent protein kinase interacting domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 6.3 0.00014 0.16 12 94 .. 187 269 .. 180 275 .. 0.72 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00014 PRKG1_interact 12 enerLkekleelkkelaeiksklekvkqkqe.slskrssllele..krEkralerkiseleeelkvleeLkaeNqrLkdENgALiR 94 e e +k +l l+k+++ ++ l++ q++e +s++ + lel ++E+ral +++s+le++ e+Lk e L dEN+ L+ FUN_001930-T1 187 EMEGIKLELVILQKQVEANTRSLSSNLQSEEtIISEELQPLELArlRNENRALTQRLSDLENS---YESLKREARSLLDENKSLVT 269 555566666666777766666666655544324566666666653369*************97...57899************985 PP >> SKA2 Spindle and kinetochore-associated protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.1 0.64 7.5e+02 41 62 .. 182 203 .. 174 208 .. 0.89 2 ? 12.0 0.4 0.00017 0.2 41 76 .. 237 272 .. 228 278 .. 0.87 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.64 SKA2 41 vkLlerlkklkeelqaLkeqce 62 ++L ++++ +k el L++q+e FUN_001930-T1 182 CELFAEMEGIKLELVILQKQVE 203 689999**************97 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00017 SKA2 41 vkLlerlkklkeelqaLkeqceellaekqelvdkir 76 + L +rl+ l++ +++Lk++ + ll e + lv+++r FUN_001930-T1 237 RALTQRLSDLENSYESLKREARSLLDENKSLVTALR 272 67999*************************999987 PP >> V_ATPase_I V-type ATPase 116kDa subunit family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 1.7 0.0001 0.12 33 126 .. 189 285 .. 184 317 .. 0.73 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.0001 V_ATPase_I 33 delerklrfleeelekaeelllkkeea..eeeeeapeekeideleeklekleeelkelnenleklkkklneltelkavlekakeffeea.eeeeee 125 + ++ +l +l++++e ++ l ++ ++ + +e+ ++ e+ +l+++ + l+++l++l++++e+lk++ ++l + ++ l +a ++++++ ++ +++ FUN_001930-T1 189 EGIKLELVILQKQVEANTRSLSSNLQSeeTIISEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNNEiDKGNKH 284 55667788999999996655555544433555677889999*******************************999999999999998873333332 PP V_ATPase_I 126 e 126 + FUN_001930-T1 285 S 285 2 PP >> Spectrin_SESTD1 SESTD1-like, spectrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.4 0.00016 0.19 23 69 .. 219 265 .. 200 292 .. 0.82 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00016 Spectrin_SESTD1 23 llctdvkaedvasiekelkeLeekveevekaleslrekGqslldels 69 +++ ++++ ++a +e ++L+++++++e+++esl+ + +sllde + FUN_001930-T1 219 IISEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENK 265 56778899999999******************************855 PP >> DUF4763 Domain of unknown function (DUF4763) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 5.6 0.00028 0.32 46 147 .. 184 282 .. 182 287 .. 0.82 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00028 DUF4763 46 iydelekiKqrvlqlrkkLilnvpdcpeidecededlelelltseqlellqLqrqnhkLrcqlselqqhlkasrksLkelrnslcqekkrlqklqk 141 ++e+e iK + l+k++ n++ + ++ ++ + + + lel L+ +n L ++ls+l+ ++++ + + + l ++ + ++l+ l FUN_001930-T1 184 LFAEMEGIKLELVILQKQVEANTRSLS---SNLQSEETIISEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNN 276 57899*****************98444...4444444444444479**************************999999999999999999999998 PP DUF4763 142 elneld 147 e+++ + FUN_001930-T1 277 EIDKGN 282 888755 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 1.1 0.00046 0.53 100 172 .. 193 265 .. 190 291 .. 0.81 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00046 DUF4407 100 leLkiFekeIdqeldeekneeadaakaqlaqalraelaelqaqiaalqaeidaaekeldelqkearcelegtk 172 leL+i +k +++ ++ +++ + ++ ela+l+++ +al + ++ +e+ ++ l++ear+ l+ +k FUN_001930-T1 193 LELVILQKQVEANTRSLSSNLQSEETIISEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENK 265 78888888888877777777666665555555889*******************************9999876 PP >> WxL WxL domain surface cell wall-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 2.9 0.00085 0.98 24 169 .. 18 172 .. 4 214 .. 0.67 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00085 WxL 24 vdPtnP....p.pvdptdpe..pgtgttGpLsidyassldFGtqki.sskdetykakaq...kekkkeekeekkpnyvqVtDkRGtnaGWtLsvkq 108 P+ P p p+ +p p++g++G+ s++ + l G+ i +s+ +t k+ + +++ k +++ ++ + +R t W ++ FUN_001930-T1 18 PAPEPPaeplPgPA--AEPVvePDQGSSGAVSVKGSPFLLQGERLIwTSDLKTLKKFVEgtiQQHGKWSSPGGATKTFKSDNNRLTI-TWYRGKQS 110 23443343132333..33335599********************9955555666666667884445555555555555555555444.45444455 PP WxL 109 s.qfkttkgkeLkGatislknge.vasnseetsakat..sstvaleltangeatevlsaakgtGa 169 + f+ ++g Lk ++l + + +++ ++++ s+++al+ +g +++v++a +g+G FUN_001930-T1 111 TlVFQGKDGPLLKEQLVNLFQRNeAQKPIDDAD---SllSNSTALQSGGQGRKQQVMAAGEGSGL 172 55899999*****99999943331444443333...23599****9*************999885 PP >> HAUS-augmin3 HAUS augmin-like complex subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 7.0 0.00054 0.63 54 143 .. 200 283 .. 187 291 .. 0.73 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00054 HAUS-augmin3 54 ktieaspsdlkqedveeleesleeieealedle.aelqeLqkekqlkinrlnkLqlaasslsqkekaleaeeeeaakklkelqeelaaena 143 k++ea+++ l++ + +e++ +e+l+ el L++e++ +++rl++L+ sl+++ ++l +e+++ l+ l++e+ + n+ FUN_001930-T1 200 KQVEANTRSLSS-------NLQSEETIISEELQpLELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNNEIDKGNK 283 455543333333.......2222223344455424899**************************************999999999888775 PP >> ADIP Afadin- and alpha -actinin-Binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.1 1.7 1.9e+03 91 114 .. 201 224 .. 197 228 .. 0.75 2 ? 12.1 4.0 0.00018 0.21 67 121 .. 228 282 .. 224 286 .. 0.94 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1.7 ADIP 91 lleakerqlekklktleqklknek 114 ++ea++r+l +l+++e+ + +e FUN_001930-T1 201 QVEANTRSLSSNLQSEETIISEEL 224 578888888888888888877765 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00018 ADIP 67 eierlqseierlkeqledlerelalleakerqlekklktleqklknekeelqrlk 121 e++rl++e + l+++l+dle+ ++l+++ r+l ++k+l ++l+ + e+ + + FUN_001930-T1 228 ELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNNEIDKGN 282 789*********************************************9999976 PP >> BBS2_hp BBS2 hairpin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 4.3 0.00086 1 15 95 .. 200 280 .. 186 283 .. 0.90 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00086 BBS2_hp 15 eelqevrerLsaeiadksnlikelvvraeDarlledikemrklykeLkelNreliaeykirsnnheelleaLKelnqiiqk 95 ++++++ Ls+++ + ++i e + e arl ++ ++++++ ++L + + l +e + +++ l++aL+ ln+ i+k FUN_001930-T1 200 KQVEANTRSLSSNLQSEETIISEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNNEIDK 280 467778889********************************************************************9988 PP >> PI3K_P85_iSH2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 5.6 0.0029 3.4 71 121 .. 216 267 .. 181 280 .. 0.77 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.0029 PI3K_P85_iSH2 71 qekf.ekeaqphekerlqensellksrlkelheskeqLeeeLkeqkeesrel 121 +e++ ++e qp e rl ++++ l++rl+ l++s e+L+ e ++ +e+++l FUN_001930-T1 216 EETIiSEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSL 267 3443134459*****************************9999888888776 PP >> Nup54 Nucleoporin complex subunit 54 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.9 6.5 0.0073 8.4 73 128 .. 228 283 .. 196 290 .. 0.83 Alignments for each domain: == domain 1 score: 6.9 bits; conditional E-value: 0.0073 Nup54 73 rieeakrrhtelshRllrllrklevlrnrgyalspeEeelrkkleelekqlndpaq 128 ++++++++ +l++Rl l + e l++ +++l +e + l + l+ l++++++ ++ FUN_001930-T1 228 ELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNNEIDKGNK 283 57899*********************************************997654 PP >> Uso1_p115_C Uso1 / p115 like vesicle tethering protein, C terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.1 2.5 2.9e+03 17 35 .. 199 217 .. 184 230 .. 0.57 2 ? 13.3 2.4 9.4e-05 0.11 9 67 .. 228 283 .. 221 294 .. 0.87 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2.5 Uso1_p115_C 17 aeelkaeLqelkkqaesle 35 +++ +a++++l+++++s+e FUN_001930-T1 199 QKQVEANTRSLSSNLQSEE 217 3444444444444444444 PP == domain 2 score: 13.3 bits; conditional E-value: 9.4e-05 Uso1_p115_C 9 easslkdeaeelkaeLqelkkqaesleqkeseakeleaevkkleeelkklkaeleeeke 67 e++ l++e+++l ++L++l++++esl+++ a+ l +e+k+l +l l +e+++ ++ FUN_001930-T1 228 ELARLRNENRALTQRLSDLENSYESLKRE---ARSLLDENKSLVTALRLLNNEIDKGNK 283 56889************************...*************99999999988544 PP >> FapA Flagellar Assembly Protein A beta solenoid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 5.7 6.6e+03 142 173 .. 110 140 .. 106 165 .. 0.60 2 ? 9.2 2.3 0.001 1.2 161 237 .. 191 268 .. 175 292 .. 0.57 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 5.7 FapA 142 kteievgvdepelkekleeleeelkeleeele 173 t ++ g d p lke+l +l ++ + + ++ FUN_001930-T1 110 STLVFQGKDGPLLKEQLVNLFQRNEAQ-KPID 140 567777888888888887777654433.3444 PP == domain 2 score: 9.2 bits; conditional E-value: 0.001 FapA 161 leeelkeleeeleklkkklkklpk.kaekqldeekkeqleklletkekleeeleeleeelkelkeeleskkeeakikv 237 ++ el l++++e ++ l+++ + +++ +e + +l++l+++ l ++l++le+ +++lk e +s ++e+k v FUN_001930-T1 191 IKLELVILQKQVEANTRSLSSNLQsEETIISEELQPLELARLRNENRALTQRLSDLENSYESLKREARSLLDENKSLV 268 444555555555555555555555344444444455667777777777777777777777777777777755553333 PP >> CCDC-167 Coiled-coil domain-containing protein 167 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 7.8 0.0048 5.5 8 66 .. 201 258 .. 194 274 .. 0.88 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0048 CCDC-167 8 kleeklasckerlervekklrkeelseedRkeLekeleelkekleknekeLkkLrkENr 66 ++e ++ s+ +l++ e + +eel++ + ++L +e ++l+++l++ e++ ++L++E r FUN_001930-T1 201 QVEANTRSLSSNLQS-EETIISEELQPLELARLRNENRALTQRLSDLENSYESLKREAR 258 577888888888876.6678899999999***************************976 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.1 6.4 7.4e+03 38 57 .. 184 203 .. 182 214 .. 0.78 2 ? 11.2 0.9 0.00037 0.43 35 62 .. 229 256 .. 221 258 .. 0.89 3 ? 6.7 1.1 0.0097 11 29 58 .. 251 280 .. 249 284 .. 0.91 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 6.4 bZIP_1 38 LekeNksLkseleelkkeve 57 L +e++ k el l+k+ve FUN_001930-T1 184 LFAEMEGIKLELVILQKQVE 203 56788888888888888876 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00037 bZIP_1 35 vkaLekeNksLkseleelkkevekLksk 62 + L +eN +L ++l+ l++ +e+Lk + FUN_001930-T1 229 LARLRNENRALTQRLSDLENSYESLKRE 256 6789**********************87 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0097 bZIP_1 29 eeLerrvkaLekeNksLkseleelkkevek 58 e L+r++ L eNksL l l++e++k FUN_001930-T1 251 ESLKREARSLLDENKSLVTALRLLNNEIDK 280 78*************************985 PP >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 1.1 0.55 6.3e+02 11 53 .. 200 244 .. 181 249 .. 0.55 2 ? 9.6 1.6 0.0016 1.9 10 57 .. 236 283 .. 227 298 .. 0.71 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.55 YabA 11 eeleeqleellkeleelkeelaelle..enaeLeiEnekLrerlk 53 +++e ++++l ++l++ + ++e l+ e a+L+ En+ L +rl+ FUN_001930-T1 200 KQVEANTRSLSSNLQSEETIISEELQplELARLRNENRALTQRLS 244 334444444444444444444444433345677778888877774 PP == domain 2 score: 9.6 bits; conditional E-value: 0.0016 YabA 10 leeleeqleellkeleelkeelaelleenaeLeiEnekLrerlkkeee 57 + l+++l++l +++e+lk+e +ll+en++L + + L ++++k ++ FUN_001930-T1 236 NRALTQRLSDLENSYESLKREARSLLDENKSLVTALRLLNNEIDKGNK 283 456788888888888888888888888888888877777777743333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (329 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1515 (0.0593071); expected 510.9 (0.02) Passed bias filter: 1024 (0.0400861); expected 510.9 (0.02) Passed Vit filter: 135 (0.00528479); expected 25.5 (0.001) Passed Fwd filter: 22 (0.000861225); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 22 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 3125.57 // Query: FUN_001931-T1 [L=275] Description: FUN_001931 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-07 29.1 10.1 0.0013 19.2 0.9 2.6 2 zf-CCHC Zinc knuckle 1.7e-05 25.0 8.2 0.00063 20.0 1.4 2.4 2 zf-CCHC_2 Zinc knuckle ------ inclusion threshold ------ 0.018 15.2 8.3 0.098 12.9 2.2 2.5 2 zf-CCHC_5 GAG-polyprotein viral zinc-finger 1.4 9.3 5.0 0.46 10.9 0.3 2.1 2 zf-CCHC_3 Zinc knuckle 6 7.1 5.7 29 4.9 0.3 2.3 2 zf-CCHC_4 Zinc knuckle Domain annotation for each model (and alignments): >> zf-CCHC Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.9 2.6e-07 0.0013 2 17 .. 54 69 .. 52 69 .. 0.93 2 ! 14.1 2.6 1.1e-05 0.055 2 17 .. 73 88 .. 72 89 .. 0.89 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 2.6e-07 zf-CCHC 2 kCynCGepGHiardCp 17 C C ++GHia+dCp FUN_001931-T1 54 ECDICEKTGHIAKDCP 69 6999***********9 PP == domain 2 score: 14.1 bits; conditional E-value: 1.1e-05 zf-CCHC 2 kCynCGepGHiardCp 17 C +CG+ GH+ rdC FUN_001931-T1 73 NCLRCGQAGHLYRDCR 88 5889***********7 PP >> zf-CCHC_2 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.8 0.00046 2.4 6 20 .. 55 69 .. 54 69 .. 0.95 2 ! 20.0 1.4 1.2e-07 0.00063 6 20 .. 74 88 .. 74 89 .. 0.95 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00046 zf-CCHC_2 6 ChiCgkkGHyIqdCP 20 C iC k+GH +dCP FUN_001931-T1 55 CDICEKTGHIAKDCP 69 88************9 PP == domain 2 score: 20.0 bits; conditional E-value: 1.2e-07 zf-CCHC_2 6 ChiCgkkGHyIqdCP 20 C +Cg+ GH+++dC+ FUN_001931-T1 74 CLRCGQAGHLYRDCR 88 9*************8 PP >> zf-CCHC_5 GAG-polyprotein viral zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.4 0.0036 18 5 18 .. 55 68 .. 51 71 .. 0.90 2 ? 12.9 2.2 1.9e-05 0.098 3 19 .. 72 88 .. 70 90 .. 0.93 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.0036 zf-CCHC_5 5 CpRCkkgkHwardC 18 C C k H a+dC FUN_001931-T1 55 CDICEKTGHIAKDC 68 777*********** PP == domain 2 score: 12.9 bits; conditional E-value: 1.9e-05 zf-CCHC_5 3 glCpRCkkgkHwardCh 19 g C+RC++ H rdC+ FUN_001931-T1 72 GNCLRCGQAGHLYRDCR 88 78**************8 PP >> zf-CCHC_3 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.5 0.2 1e+03 6 20 .. 54 68 .. 50 72 .. 0.80 2 ? 10.9 0.3 9e-05 0.46 6 27 .. 73 94 .. 69 99 .. 0.85 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.2 zf-CCHC_3 6 rCQKClkkGHwtYEC 20 C C k+GH + C FUN_001931-T1 54 ECDICEKTGHIAKDC 68 6888******87666 PP == domain 2 score: 10.9 bits; conditional E-value: 9e-05 zf-CCHC_3 6 rCQKClkkGHwtYECkgerkYv 27 C +C++ GH+ C++e ++ FUN_001931-T1 73 NCLRCGQAGHLYRDCRNEPVAA 94 699*************997765 PP >> zf-CCHC_4 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.3 0.0056 29 34 49 .] 55 70 .. 52 70 .. 0.93 2 ? 4.4 1.0 0.0082 42 33 48 .. 73 88 .. 71 89 .. 0.89 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0056 zf-CCHC_4 34 CfiCgrlgHsdkfCpk 49 C iC gH k+Cp+ FUN_001931-T1 55 CDICEKTGHIAKDCPF 70 99************95 PP == domain 2 score: 4.4 bits; conditional E-value: 0.0082 zf-CCHC_4 33 fCfiCgrlgHsdkfCp 48 C Cg gH ++C+ FUN_001931-T1 73 NCLRCGQAGHLYRDCR 88 599************7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (275 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 629 (0.0246232); expected 510.9 (0.02) Passed bias filter: 349 (0.0136622); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 2694.39 // Query: FUN_001932-T1 [L=448] Description: FUN_001932 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-70 238.5 0.1 1.6e-70 237.9 0.1 1.3 1 Trypsin Trypsin 1.9e-22 80.3 0.0 2.7e-22 79.8 0.0 1.2 1 MAM MAM domain, meprin/A5/mu 0.00022 22.5 0.1 0.0015 19.8 0.0 2.1 2 Trypsin_2 Trypsin-like peptidase domain Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 237.9 0.1 1.8e-74 1.6e-70 1 220 [] 214 441 .. 214 441 .. 0.98 Alignments for each domain: == domain 1 score: 237.9 bits; conditional E-value: 1.8e-74 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvlTAaHCvsn..assvkvvlgehnisksegseqklkvekvivhpnynsdt.ldnDiallk 93 ivgg++a++g++pwq++l ssg CGG+l+ ++w++TAaHC++ assv v+lg++ ++ + g+eq + v k+i hp yn ++ + +Diallk FUN_001932-T1 214 IVGGTDAKPGDWPWQGMLRTSSGFPYCGGTLLAPEWLVTAAHCIETqtASSVFVRLGAYIRTANVGTEQDFRVIKIIKHPSYNNPKrYSHDIALLK 309 89*********************999********************88888889*****************************99999******** PP Trypsin 94 lkspvtlgdavrpiclpaassslavgttclvsGwGntkelg.lsdtlqevnvpvvsreecrsayggkvtdnmicagak.ggkdacqGDSGGPlvcs 187 l++p+ l +v+ +clp++ + + +t+c+++GwG+ +++g ++d+lq+++vp+ +r++c++ay++++ d+micag + gg d+cqGDSGGP+vc+ FUN_001932-T1 310 LDKPAALDRNVALACLPQNVAAPGDNTKCWITGWGRLSSGGgTPDKLQQASVPIAGRDRCDKAYPRRIHDSMICAGLDqGGIDSCQGDSGGPMVCE 405 ******************88888*************999999************************************999*************** PP Trypsin 188 dg...eliGivswgkgcasgnkpgvytrvssyadwi 220 +g +l+G++swg+gcas++k gvy++v+ +++wi FUN_001932-T1 406 NGgryYLQGVTSWGYGCASPGKFGVYAKVKFLLPWI 441 ***********************************8 PP >> MAM MAM domain, meprin/A5/mu # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.8 0.0 3.2e-26 2.7e-22 1 155 [. 20 166 .. 20 169 .. 0.92 Alignments for each domain: == domain 1 score: 79.8 bits; conditional E-value: 3.2e-26 MAM 1 CdFeegslCgw.tqdesddadWervsaa..sektgpssdhtetgsGhyllletssa.eegqtarLlspllpasaksqClrFwyhmsgsskgtlrvl 92 C+F++g lC+ +q+ +d++dW+++++ s+ tgps d + g+G+y ++e+ss ++g++a L + +s + +C++F+y+m+g+++g lrvl FUN_001932-T1 20 CNFDSGGLCQGvSQSRNDKFDWSVRKGItpSSGTGPSGDIN--GNGYYAYIEASSPrRPGDNALLDFDSDLSSGS-TCISFSYQMNGRDVGGLRVL 112 *********95489999999*****99999999******99..************99********9988888877.9******************* PP MAM 93 lreegeekeellwsisgeqgksWkeaevtlsklekefqvvfeavrgggsegdialDdislseg 155 ++ + e +s +g++g++W + +t+ +v+fe++rg g +gdia+D++s+ + FUN_001932-T1 113 VNGNVE------FSSKGSKGTKWIKKMMTIAG-VAAKKVTFEGIRGPGWQGDIAIDEVSI--K 166 976655......599*****************.9999**********************9..4 PP >> Trypsin_2 Trypsin-like peptidase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 0.27 2.3e+03 38 90 .. 60 117 .. 48 177 .. 0.51 2 ! 19.8 0.0 1.8e-07 0.0015 3 140 .. 242 407 .. 240 410 .. 0.60 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.27 Trypsin_2 38 dgreyaatvvaadpel..Dlallkv.sedgaglpplplgd..saplvggervyavGyp 90 +g+ y a + a +p++ D all + s+ ++g +++ ++ vgg rv++ G+ FUN_001932-T1 60 NGNGYYAYIEASSPRRpgDNALLDFdSDLSSGSTCISFSYqmNGRDVGGLRVLVNGNV 117 5556666666666666667777777544444444444444334466666666666663 PP == domain 2 score: 19.8 bits; conditional E-value: 1.8e-07 Trypsin_2 3 GfvvssdglvlTnaHvvadaeeaav.....vaekvsvaladgreyaatvvaadp........elDlallkv.....sedgaglpplplgdsa..pl 78 G +++++ ++T+aH+++ ++++ v + ++++ + + +++ p +D+allk+ +++ +l++lp +a + FUN_001932-T1 242 GTLLAPEW-LVTAAHCIETQTASSVfvrlgAYIRTANVGTEQDFRVIKIIKH-PsynnpkrySHDIALLKLdkpaaLDRNVALACLPQNVAApgDN 335 77888887.****************877742223333333333333333333.35788898888*******8887755555666666333331033 PP Trypsin_2 79 vggervyavGy...plggekleslseGtvsavse...srderddeell.....qtdaslspGsSGgPlfdaeG 140 +++ +G+ +g +++ + ++ +++ ++ + r +++++ q ++ G SGgP + ++G FUN_001932-T1 336 TKC-WITGWGRlssGGGTPDKLQQASVPIAGRDRcdkAYPRRIHDSMIcagldQGGIDSCQGDSGGPMVCENG 407 333.555555553223333333555556666666776555555555558899855555555999999998665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (448 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 406 (0.0158935); expected 510.9 (0.02) Passed bias filter: 306 (0.0119789); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 4500.21 // Query: FUN_001933-T1 [L=591] Description: FUN_001933 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-71 236.9 7.1 8.7e-15 55.5 0.1 6.8 5 Ig_3 Immunoglobulin domain 1e-67 224.7 0.2 1.2e-14 54.6 0.0 7.2 7 I-set Immunoglobulin I-set domain 2.2e-50 169.3 2.9 3e-10 40.8 0.0 6.4 5 ig Immunoglobulin domain 1.6e-43 147.2 12.8 3.3e-10 40.5 0.2 6.4 5 Ig_2 Immunoglobulin domain 3.9e-32 111.2 5.0 0.00016 22.3 0.0 7.7 5 V-set Immunoglobulin V-set domain 1.1e-10 41.9 0.0 0.0083 16.6 0.0 4.7 5 C2-set_3 Butyrophilin subfamily 3 member A2-like, 2.8e-08 34.2 2.7 0.052 14.1 0.0 4.9 6 C2-set_2 CD80-like C2-set immunoglobulin domain 1e-07 32.7 0.1 1.8 9.5 0.0 6.3 5 Ig_5 Ig-like domain on T-cell surface glycopr 9.1e-07 29.4 1.1 0.14 12.6 0.0 4.0 5 Ig_PDGFR_d4 Platelet-derived growth factor receptor 2.6e-06 27.8 1.2 0.56 10.5 0.0 5.1 5 Ig_6 Immunoglobulin domain 7e-06 27.0 0.9 3.4 8.8 0.0 5.7 5 Ig_4 T-cell surface glycoprotein CD3 delta ch 9.3e-06 26.1 1.0 0.0084 16.6 0.0 5.1 6 Ig_C17orf99 C17orf99 Ig domain 1.1e-05 25.6 7.1 9.3 6.6 0.2 5.9 5 Adeno_E3_CR1 Adenovirus E3 region protein CR1 0.00012 22.8 1.2 3.3 8.6 0.0 4.6 3 C1-set Immunoglobulin C1-set domain 0.00035 21.2 0.5 2.4 8.8 0.0 3.1 3 FixG_C IG-like fold at C-terminal of FixG, puta 0.00049 20.8 0.8 5.3 7.8 0.0 4.2 5 Receptor_2B4 Natural killer cell receptor 2B4 0.00091 20.0 0.0 1.9 9.4 0.0 2.5 2 Dynein_light Dynein light chain type 1 0.0014 19.4 0.0 3.7 8.3 0.0 2.7 2 Pox_vIL-18BP Orthopoxvirus interleukin 18 binding pro 0.0018 18.7 0.0 49 4.4 0.0 4.6 5 Izumo-Ig Izumo-like Immunoglobulin domain 0.0064 16.9 0.4 0.68 10.4 0.1 3.7 4 Lep_receptor_Ig Ig-like C2-type domain ------ inclusion threshold ------ 0.01 16.5 4.9 1.3e+02 3.2 0.0 5.8 7 Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain 0.012 16.0 0.2 6.2 7.1 0.0 2.4 2 DUF4960 Domain of unknown function (DUF4960) 0.037 14.5 0.0 45 4.6 0.0 3.7 4 BARF1_ig2 BARF1 second Ig-like domain 0.27 11.7 0.1 49 4.5 0.0 2.5 2 Syndecan Syndecan domain Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.7 0.1 4.5e-15 4.8e-12 2 78 .] 26 106 .. 25 106 .. 0.88 2 ! 55.5 0.1 8.2e-18 8.7e-15 12 78 .] 138 205 .. 123 205 .. 0.85 3 ! 38.2 0.0 2.1e-12 2.2e-09 1 78 [] 227 332 .. 227 332 .. 0.88 4 ! 54.6 0.1 1.5e-17 1.6e-14 12 78 .] 367 434 .. 352 434 .. 0.84 5 ! 38.0 0.0 2.3e-12 2.4e-09 1 78 [] 456 561 .. 456 561 .. 0.88 Alignments for each domain: == domain 1 score: 46.7 bits; conditional E-value: 4.5e-15 Ig_3 2 Pvitvspsstv...veegesvtLtCea..egnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P+i+ + ++++ v +g +++L C++ ++ ++p + W kn+++l++ s+ + ++++ ++ L+i+nvt+ed+G Y CvA+N FUN_001933-T1 26 PTIRNKGNKVEvtrVPKGRDARLICTVkeTSRNKPIVFWVKNNETLQPASHNR-MRVKPYRYLRIKNVTEEDAGFYACVAKN 106 677766666666689************99999999*********977766654.99*************************9 PP == domain 2 score: 55.5 bits; conditional E-value: 8.2e-18 Ig_3 12 vveegesvtLtCeaegnppptitWykngkelssgstskr.sssssnstLtisnvtredsGtYtCvAsN 78 v+ +g+++++ C+a+g+p+pt++Wyk++ ++ + s++ ++++ +++L+i+n+ + d+G YtC +sN FUN_001933-T1 138 VLPVGNTIKMDCSATGYPKPTVKWYKDNALYQERNGSSKfNRGTFQTVLIIRNAVPADRGLYTCNVSN 205 4789*************************8444444444699999**********************9 PP == domain 3 score: 38.2 bits; conditional E-value: 2.1e-12 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppptitWykngke...lssgstskr.............................sssssnstLtisnv 64 kP+i + t + ege++tL C+a +++ p+++W++ + s++++ + + ++ +L+++nv FUN_001933-T1 227 KPKILKMENAT-AMEGENATLFCKALSDSMPHFQWLRWLAPpsnA---SDESSqiknpvyevikqnqqngnkhsllpigkpaQLDFHGVKLILTNV 318 89999766666.6***************************95431...333335678************************999999********* PP Ig_3 65 tredsGtYtCvAsN 78 +++d+G+Y+C++ N FUN_001933-T1 319 SKKDEGKYSCIVGN 332 ***********987 PP == domain 4 score: 54.6 bits; conditional E-value: 1.5e-17 Ig_3 12 vveegesvtLtCeaegnppptitWykngke..lssgstskr.sssssnstLtisnvtredsGtYtCvAsN 78 v+ +g+++++ C+a+g+p+pt++Wyk++ +g +s + ++++ +++L+i+n+ + d+G YtC +sN FUN_001933-T1 367 VLPVGNTIKMDCSATGYPKPTVKWYKDNALyqVRNG-SS-KfNRGTFQTVLIIRNAVPADRGLYTCNVSN 434 4789*************************8643332.22.2599999**********************9 PP == domain 5 score: 38.0 bits; conditional E-value: 2.3e-12 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppptitWykngke...lssgstskr.............................sssssnstLtisnv 64 kP+i + t + ege++tL C+a +++ p+++W++ + s++++ + + ++ +L+++nv FUN_001933-T1 456 KPKILKMENAT-AMEGENATLFCKALSDSMPHFQWLRWLAPpsnA---SDESSqiknpvyevikqnqqngnkhsllpigkpaKLDFHGVKLILTNV 547 89999766666.6***************************95431...333335678************************999999********* PP Ig_3 65 tredsGtYtCvAsN 78 +++d+G+Y+C++ N FUN_001933-T1 548 SKKDEGKYSCIVGN 561 ***********987 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.8 0.0 1.7e-16 1.8e-13 7 88 .. 35 117 .. 29 119 .. 0.91 2 ! 54.6 0.0 1.1e-17 1.2e-14 10 90 .] 137 218 .. 130 218 .. 0.86 3 ! 10.2 0.0 0.00079 0.84 6 36 .. 232 262 .. 229 283 .. 0.87 4 ! 17.9 0.0 3.2e-06 0.0034 56 89 .. 311 344 .. 293 345 .. 0.86 5 ! 53.1 0.0 3.3e-17 3.6e-14 10 90 .] 366 447 .. 359 447 .. 0.86 6 ! 10.2 0.0 0.00079 0.84 6 36 .. 461 491 .. 458 512 .. 0.87 7 ! 18.0 0.0 3e-06 0.0032 56 89 .. 540 573 .. 521 574 .. 0.85 Alignments for each domain: == domain 1 score: 50.8 bits; conditional E-value: 1.7e-16 I-set 7 lkdvevkeGesaeleckvsGe..pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeL 88 ++ + v +G +a+l c+v+ + +p v W+k+++ l++ ++ +++ + L+I+nv++eD+G Y c+a+ns g+++ + +L FUN_001933-T1 35 VEVTRVPKGRDARLICTVKETsrNKPIVFWVKNNETLQPASHNRMRVKP-YRYLRIKNVTEEDAGFYACVAKNSCGRNSLTWRL 117 56678999**********9986679***********************9.778************************9988777 PP == domain 2 score: 54.6 bits; conditional E-value: 1.1e-17 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee.gtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +++ +G++++++c+++G p+p+v+W+kd+ +e + + +++ ++ L+I+n+ ++D G Ytc+++n +g + s +++V FUN_001933-T1 137 IVLPVGNTIKMDCSATGYPKPTVKWYKDNALYQERNGSSKFNRGtFQTVLIIRNAVPADRGLYTCNVSNAYGWISNSYRVHV 218 67789************************999994444444444599*************************9988888876 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00079 I-set 6 klkdvevkeGesaeleckvsGepepevsWlk 36 k+++++++eGe+a+l ck+ + p+++Wl+ FUN_001933-T1 232 KMENATAMEGENATLFCKALSDSMPHFQWLR 262 67899************************87 PP == domain 4 score: 17.9 bits; conditional E-value: 3.2e-06 I-set 56 atLtIsnvkkeDeGkYtckatnsageaeasaeLt 89 +L+++nv+k+DeGkY+c + n +g a ++a + FUN_001933-T1 311 VKLILTNVSKKDEGKYSCIVGNPFGYAVQQAYVI 344 689**********************998887765 PP == domain 5 score: 53.1 bits; conditional E-value: 3.3e-17 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +++ +G++++++c+++G p+p+v+W+kd+ + + + k+++ ++ L+I+n+ ++D G Ytc+++n +g + s +++V FUN_001933-T1 366 IVLPVGNTIKMDCSATGYPKPTVKWYKDNALYQVrNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNAYGWISNSYRVHV 447 67789***********************9999983344444444599*************************9988888876 PP == domain 6 score: 10.2 bits; conditional E-value: 0.00079 I-set 6 klkdvevkeGesaeleckvsGepepevsWlk 36 k+++++++eGe+a+l ck+ + p+++Wl+ FUN_001933-T1 461 KMENATAMEGENATLFCKALSDSMPHFQWLR 491 67899************************87 PP == domain 7 score: 18.0 bits; conditional E-value: 3e-06 I-set 56 atLtIsnvkkeDeGkYtckatnsageaeasaeLt 89 +L+++nv+k+DeGkY+c + n +g a ++a + FUN_001933-T1 540 VKLILTNVSKKDEGKYSCIVGNAFGYAVQQAYVI 573 689**********************998887765 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.2 0.0 3.7e-12 4e-09 3 75 .. 38 109 .. 36 114 .. 0.92 2 ! 40.8 0.0 2.8e-13 3e-10 3 73 .. 137 206 .. 135 209 .. 0.96 3 ! 24.2 0.0 4.1e-08 4.3e-05 3 75 .. 236 335 .. 234 338 .. 0.80 4 ! 37.6 0.0 2.7e-12 2.9e-09 3 73 .. 366 435 .. 364 438 .. 0.89 5 ! 23.2 0.0 8.5e-08 9e-05 3 74 .. 465 563 .. 463 567 .. 0.80 Alignments for each domain: == domain 1 score: 37.2 bits; conditional E-value: 3.7e-12 ig 3 vtvleGesatLtCsas.egspgpdvtWskegktkieslkvkedngrttqs...sllisnvteedaGtYtCvvnnpgg 75 + v++G a+L C+++ +++ p+v+W k+++t++ ++ +r+++ l i nvteedaG+Y Cv+ n+ g FUN_001933-T1 38 TRVPKGRDARLICTVKeTSRNKPIVFWVKNNETLQPASH-----NRMRVKpyrYLRIKNVTEEDAGFYACVAKNSCG 109 57899**********************************.....99999988889******************9866 PP == domain 2 score: 40.8 bits; conditional E-value: 2.8e-13 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++++G+++ + Csa+ g p p+v+W k++ +e + n++t+q+ l i+n+ + d G YtC v+n+ FUN_001933-T1 137 IVLPVGNTIKMDCSAT-GYPKPTVKWYKDNALYQERNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNA 206 6899************.**************9999999999****************************97 PP == domain 3 score: 24.2 bits; conditional E-value: 4.1e-08 ig 3 vtvleGesatLtCsasegspgpdvtWsk....egktkieslk.........vkedngrttqs..................sllisnvteedaGtYt 67 t+ eGe+atL C+a +++ p+++W + + ++es++ + ++++ ++ l + nv+++d+G Y+ FUN_001933-T1 236 ATAMEGENATLFCKAL-SDSMPHFQWLRwlapPSNASDESSQiknpvyeviK---QNQQNGNkhsllpigkpaqldfhgvKLILTNVSKKDEGKYS 327 56779***********.*********99555555666666669999987542...22222223568****************************** PP ig 68 Cvvnnpgg 75 C v np g FUN_001933-T1 328 CIVGNPFG 335 ***99876 PP == domain 4 score: 37.6 bits; conditional E-value: 2.7e-12 ig 3 vtvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++++G+++ + Csa+ g p p+v+W k++ + + n++t+q+ l i+n+ + d G YtC v+n+ FUN_001933-T1 366 IVLPVGNTIKMDCSAT-GYPKPTVKWYKDNALYQVRNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNA 435 6899************.************965555555556****************************97 PP == domain 5 score: 23.2 bits; conditional E-value: 8.5e-08 ig 3 vtvleGesatLtCsasegspgpdvtWsk....egktkieslk.........vkedngrttqs..................sllisnvteedaGtYt 67 t+ eGe+atL C+a +++ p+++W + + ++es++ + ++++ ++ l + nv+++d+G Y+ FUN_001933-T1 465 ATAMEGENATLFCKAL-SDSMPHFQWLRwlapPSNASDESSQiknpvyeviK---QNQQNGNkhsllpigkpakldfhgvKLILTNVSKKDEGKYS 556 56779***********.*********99555555666666669999987542...22222223568****************************** PP ig 68 Cvvnnpg 74 C v n+ FUN_001933-T1 557 CIVGNAF 563 **98876 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.4 0.1 2.6e-11 2.7e-08 6 70 .. 35 110 .. 25 119 .. 0.80 2 ! 40.5 0.2 3.1e-13 3.3e-10 9 79 .] 137 218 .. 126 218 .. 0.80 3 ! 17.4 0.0 5.1e-06 0.0054 3 66 .. 230 333 .. 227 345 .. 0.82 4 ! 40.5 0.2 3.2e-13 3.4e-10 9 79 .] 366 447 .. 355 447 .. 0.80 5 ! 17.2 0.0 5.8e-06 0.0062 3 66 .. 459 562 .. 456 574 .. 0.82 Alignments for each domain: == domain 1 score: 34.4 bits; conditional E-value: 2.6e-11 Ig_2 6 asptvvtegesvtLtCsas..gnppakytwykdgkvls.ssqn........fft.snvsaedsGtYtCtarntkggk 70 ++ t+v++g + +L C+++ ++ ++ + w k+++ l+ s+n +++ +nv++ed+G Y C+a+n+ g FUN_001933-T1 35 VEVTRVPKGRDARLICTVKetSRNKPIVFWVKNNETLQpASHNrmrvkpyrYLRiKNVTEEDAGFYACVAKNS-CGR 110 55699**************8765568899*****999964666788998886656****************94.344 PP == domain 2 score: 40.5 bits; conditional E-value: 3.1e-13 Ig_2 9 tvvtegesvtLtCsasgnppakytwykdg...kvlsssqn.........fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 v++ g ++++ Csa g p+++++wykd+ ++ + s + ++++n+ + d+G YtC ++n ++g sn+ +++v FUN_001933-T1 137 IVLPVGNTIKMDCSATGYPKPTVKWYKDNalyQERNGSSKfnrgtfqtvLIIRNAVPADRGLYTCNVSN-AYGWISNSYRVHV 218 57899************************55533332222556677776777*****************.7788888777766 PP == domain 3 score: 17.4 bits; conditional E-value: 5.1e-06 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdg..................kvlsssqn......................fftsnvsaedsGt 58 +l ++ + +ege+ tL C+a ++ + ++w + +v++++q+ ++++nvs d G FUN_001933-T1 230 ILKMENATAMEGENATLFCKALSDSMPHFQWLRWLappsnasdessqiknpvyEVIKQNQQngnkhsllpigkpaqldfhgvkLILTNVSKKDEGK 325 566777899************9887788888877766789999999999999988885444477999999999999998888666699******** PP Ig_2 59 YtCtarnt 66 Y+C ++n+ FUN_001933-T1 326 YSCIVGNP 333 *****996 PP == domain 4 score: 40.5 bits; conditional E-value: 3.2e-13 Ig_2 9 tvvtegesvtLtCsasgnppakytwykdg...kvlsssqn.........fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 v++ g ++++ Csa g p+++++wykd+ +v + s + ++++n+ + d+G YtC ++n ++g sn+ +++v FUN_001933-T1 366 IVLPVGNTIKMDCSATGYPKPTVKWYKDNalyQVRNGSSKfnrgtfqtvLIIRNAVPADRGLYTCNVSN-AYGWISNSYRVHV 447 57899************************66644443333456667776777*****************.7788888777766 PP == domain 5 score: 17.2 bits; conditional E-value: 5.8e-06 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdg..................kvlsssqn......................fftsnvsaedsGt 58 +l ++ + +ege+ tL C+a ++ + ++w + +v++++q+ ++++nvs d G FUN_001933-T1 459 ILKMENATAMEGENATLFCKALSDSMPHFQWLRWLappsnasdessqiknpvyEVIKQNQQngnkhsllpigkpakldfhgvkLILTNVSKKDEGK 554 566777899************9887788888877766789999999999999988885544477999999999999998888666699******** PP Ig_2 59 YtCtarnt 66 Y+C ++n FUN_001933-T1 555 YSCIVGNA 562 *****994 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 1.7e-05 0.018 74 106 .. 86 117 .. 33 120 .. 0.72 2 ! 20.7 0.1 4.9e-07 0.00052 9 108 .. 140 218 .. 135 219 .. 0.75 3 ! 22.3 0.0 1.5e-07 0.00016 7 104 .. 237 343 .. 233 347 .. 0.71 4 ! 20.1 0.1 7.5e-07 0.00079 9 108 .. 369 447 .. 365 448 .. 0.74 5 ! 21.1 0.0 3.5e-07 0.00038 7 103 .. 466 571 .. 462 575 .. 0.70 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1.7e-05 V-set 74 sltiqnltlsDsGtYtCavipkgevvfgkgtrL 106 l+i+n+t++D+G+Y C+ ++++++ + + rL FUN_001933-T1 86 YLRIKNVTEEDAGFYACV-AKNSCGRNSLTWRL 117 79****************.88888777666665 PP == domain 2 score: 20.7 bits; conditional E-value: 4.9e-07 V-set 9 aeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 ++G++++++Cs + + + v+Wy++++ +++ +n + +k+ +r ++++ l i+n+ ++D G+YtC+v ++ ++ ++++ FUN_001933-T1 140 PVGNTIKMDCSATGY---PKPTVKWYKDNA-------LYQERN--GSSKF-NRGTFQT-------VLIIRNAVPADRGLYTCNV-SNAYGWISNSY 214 68********99999...*********884.......455544..44334.3556777.......99****************6.55555555555 PP V-set 105 rLtV 108 r++V FUN_001933-T1 215 RVHV 218 5555 PP == domain 3 score: 22.3 bits; conditional E-value: 1.5e-07 V-set 7 tvaeGesvtLtCslssseseasqsvyWyrqppgk.epteliayysn...kseeekkkgrfslrk..dpsrsdfs...ltiqnltlsDsGtYtCav. 92 t+ eGe++tL C+ s + + q+++W p+++ +++ +i +++++++++ sl +p + df+ l ++n++ +D+G Y C v FUN_001933-T1 237 TAMEGENATLFCKALSDSMPHFQWLRWLAPPSNAsDESSQIKNP-VyevIKQNQQNGNKHSLLPigKPAQLDFHgvkLILTNVSKKDEGKYSCIVg 331 789*********88888778*********998876333333222.24654444444555555555556666653333*****************98 PP V-set 93 ipkgevvfgkgt 104 +p g+ v+++ + FUN_001933-T1 332 NPFGYAVQQAYV 343 888888877765 PP == domain 4 score: 20.1 bits; conditional E-value: 7.5e-07 V-set 9 aeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgt 104 ++G++++++Cs + + + v+Wy++++ +++ +n+s + + +r ++++ l i+n+ ++D G+YtC+v ++ ++ ++++ FUN_001933-T1 369 PVGNTIKMDCSATGY---PKPTVKWYKDNA-------LYQVRNGSSK--F-NRGTFQT-------VLIIRNAVPADRGLYTCNV-SNAYGWISNSY 443 689*******99999...*********885.......4444443333..3.3556666.......89****************6.55555555555 PP V-set 105 rLtV 108 r++V FUN_001933-T1 444 RVHV 447 5555 PP == domain 5 score: 21.1 bits; conditional E-value: 3.5e-07 V-set 7 tvaeGesvtLtCslssseseasqsvyWyrqppgk.epteliayysn...kseeekkkgrfslrk..dpsrsdfs...ltiqnltlsDsGtYtCav. 92 t+ eGe++tL C+ s + + q+++W p+++ +++ +i +++++++++ sl +p + df+ l ++n++ +D+G Y C v FUN_001933-T1 466 TAMEGENATLFCKALSDSMPHFQWLRWLAPPSNAsDESSQIKNP-VyevIKQNQQNGNKHSLLPigKPAKLDFHgvkLILTNVSKKDEGKYSCIVg 560 789*********88888778*********998876333333222.24554444444555555555556666653333****************998 PP V-set 93 ipkgevvfgkg 103 ++ g+ v+++ FUN_001933-T1 561 NAFGYAVQQAY 571 77777777665 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.53 5.7e+02 16 80 .. 45 107 .. 32 112 .. 0.66 2 ! 16.5 0.0 8.4e-06 0.009 15 79 .. 143 205 .. 137 208 .. 0.78 3 ? -0.2 0.0 1.3 1.4e+03 64 81 .. 317 334 .. 291 337 .. 0.80 4 ! 16.6 0.0 7.8e-06 0.0083 15 79 .. 372 434 .. 366 437 .. 0.77 5 ? -1.5 0.0 3.3 3.5e+03 65 80 .. 547 562 .. 529 564 .. 0.78 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.53 C2-set_3 16 girlvCrsaGW.yPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnp 80 + rl C+++ +P v W +++ +l+++s++ + ++ + v+e+ + + C+ +n+ FUN_001933-T1 45 DARLICTVKETsRNKPIVFWVKNNE-TLQPASHNRMRV--KPYRYLRIKNVTEEDAGFYACVAKNS 107 5667777665414689999998776.677666644433..45666666667888888888888887 PP == domain 2 score: 16.5 bits; conditional E-value: 8.4e-06 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvre...ssnknvsCsirn 79 + i++ C+++G yP+P+v+W++ + l ++ + s+ ++g f++ l++r+ + + ++C ++n FUN_001933-T1 143 NTIKMDCSATG-YPKPTVKWYKDNA--LYQERNGSSKFNRGTFQTV--LIIRNavpADRGLYTCNVSN 205 6799***9988.********99877..9999999999999999865..45555333556667888887 PP == domain 3 score: -0.2 bits; conditional E-value: 1.3 C2-set_3 64 vvressnknvsCsirnpl 81 v+++ ++++sC++ np+ FUN_001933-T1 317 NVSKKDEGKYSCIVGNPF 334 356677899*****9985 PP == domain 4 score: 16.6 bits; conditional E-value: 7.8e-06 C2-set_3 15 ggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvre...ssnknvsCsirn 79 + i++ C+++G yP+P+v+W++ + l ++ + s+ ++g f++ l++r+ + + ++C ++n FUN_001933-T1 372 NTIKMDCSATG-YPKPTVKWYKDNA--LYQVRNGSSKFNRGTFQTV--LIIRNavpADRGLYTCNVSN 434 6799***9988.********98876..9999999999999999865..45555333556667888887 PP == domain 5 score: -1.5 bits; conditional E-value: 3.3 C2-set_3 65 vressnknvsCsirnp 80 v+++ ++++sC++ n FUN_001933-T1 547 VSKKDEGKYSCIVGNA 562 56677899****9996 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.28 3e+02 10 47 .. 37 77 .. 26 93 .. 0.73 2 ? -1.1 0.0 2.6 2.8e+03 20 35 .. 101 116 .. 87 119 .. 0.86 3 ! 14.1 0.0 4.9e-05 0.052 15 57 .. 143 182 .. 124 206 .. 0.74 4 ? -2.2 0.0 5.9 6.3e+03 14 48 .. 241 274 .. 230 280 .. 0.60 5 ! 13.6 0.0 7.1e-05 0.076 16 53 .. 373 407 .. 356 435 .. 0.74 6 ? -2.2 0.0 5.9 6.3e+03 14 48 .. 470 503 .. 459 509 .. 0.60 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.28 C2-set_2 10 leae..ekevvatCv.saggkPapritWlldgkeleaaets 47 +++ ++ + C+ + ++ +p + W +++++l+ a+ + FUN_001933-T1 37 VTRVpkGRDARLICTvKETSRNKPIVFWVKNNETLQPASHN 77 333356778888998567899999*********99555544 PP == domain 2 score: -1.1 bits; conditional E-value: 2.6 C2-set_2 20 tCvsaggkPapritWl 35 Cv++++ + ++tW FUN_001933-T1 101 ACVAKNSCGRNSLTWR 116 6**************7 PP == domain 3 score: 14.1 bits; conditional E-value: 4.9e-05 C2-set_2 15 kevvatCvsaggkPapritWlldgkeleaaetsseqdpesglv 57 + ++C sa g+P+p++ W++d+ e + +++++ g++ FUN_001933-T1 143 NTIKMDC-SATGYPKPTVKWYKDNALY--QERNGSSKFNRGTF 182 5666789.99*************9987..55555555555554 PP == domain 4 score: -2.2 bits; conditional E-value: 5.9 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaaetss 48 +++ ++ C a + p+ +Wl+ + + + a+++s FUN_001933-T1 241 GENATLFC-KALSDSMPHFQWLRWLAPPSNASDES 274 44677777.44555557888888777764444444 PP == domain 5 score: 13.6 bits; conditional E-value: 7.1e-05 C2-set_2 16 evvatCvsaggkPapritWlldgkeleaaetsseqdpe 53 + ++C sa g+P+p++ W++d+ + + +++++ FUN_001933-T1 373 TIKMDC-SATGYPKPTVKWYKDNALY--QVRNGSSKFN 407 566789.99*************9887..3344444444 PP == domain 6 score: -2.2 bits; conditional E-value: 5.9 C2-set_2 14 ekevvatCvsaggkPapritWlldgkeleaaetss 48 +++ ++ C a + p+ +Wl+ + + + a+++s FUN_001933-T1 470 GENATLFC-KALSDSMPHFQWLRWLAPPSNASDES 503 44677777.44555557888888777764444444 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.0 0.0017 1.8 22 61 .. 62 108 .. 39 119 .. 0.62 2 ? 4.1 0.0 0.083 88 7 44 .. 142 182 .. 138 220 .. 0.66 3 ? 3.3 0.0 0.15 1.6e+02 35 59 .. 309 332 .. 302 346 .. 0.81 4 ? 2.8 0.0 0.21 2.2e+02 7 36 .. 371 402 .. 367 448 .. 0.63 5 ? 3.8 0.0 0.11 1.1e+02 35 60 .. 538 562 .. 531 575 .. 0.79 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0017 Ig_5 22 ikWekndkelkd........keekeLvlenFsevedsGyysCykessk 61 + W kn+++l+ k + L ++n e ed G+y+C++++s FUN_001933-T1 62 VFWVKNNETLQPashnrmrvKPYRYLRIKNVTE-EDAGFYACVAKNSC 108 568888766655211111113446789999999.9********99974 PP == domain 2 score: 4.1 bits; conditional E-value: 0.083 Ig_5 7 gttVtltCpeese..eeikWekndkelkdkee.keLvlenF 44 g+t+++ C+ + ++kW k++ +++++ ++ F FUN_001933-T1 142 GNTIKMDCSATGYpkPTVKWYKDNALYQERNGsSKFNRGTF 182 89999999976544489******998887554134444444 PP == domain 3 score: 3.3 bits; conditional E-value: 0.15 Ig_5 35 eekeLvlenFsevedsGyysCykes 59 ++ +L+l n s +d+G+ysC + FUN_001933-T1 309 HGVKLILTNVSK-KDEGKYSCIVGN 332 567899***999.899*****9776 PP == domain 4 score: 2.8 bits; conditional E-value: 0.21 Ig_5 7 gttVtltCpeese..eeikWekndkelkdkee 36 g+t+++ C+ + ++kW k++ + +++ FUN_001933-T1 371 GNTIKMDCSATGYpkPTVKWYKDNALYQVRNG 402 8899999997644448999*999876665433 PP == domain 5 score: 3.8 bits; conditional E-value: 0.11 Ig_5 35 eekeLvlenFsevedsGyysCykess 60 ++ +L+l n s +d+G+ysC ++ FUN_001933-T1 538 HGVKLILTNVSK-KDEGKYSCIVGNA 562 567899***999.899*****98775 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1.7 1.8e+03 89 110 .. 99 120 .. 52 128 .. 0.77 2 ! 11.9 0.0 0.00022 0.24 17 43 .. 146 172 .. 140 220 .. 0.83 3 ? -1.6 0.0 3.2 3.4e+03 2 33 .. 229 261 .. 228 291 .. 0.79 4 ! 12.6 0.0 0.00013 0.14 17 47 .. 375 405 .. 369 455 .. 0.83 5 ? -1.6 0.0 3.2 3.4e+03 2 33 .. 458 490 .. 457 520 .. 0.79 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1.7 Ig_PDGFR_d4 89 avrCeaknelgadsrevkLvss 110 + C akn+ g++s +Lv + FUN_001933-T1 99 FYACVAKNSCGRNSLTWRLVIE 120 4568888888888887777754 PP == domain 2 score: 11.9 bits; conditional E-value: 0.00022 Ig_PDGFR_d4 17 tvtCvaeGmPqPeveWfiCkdikkCsn 43 ++ C a+G+P+P+v+W+ + + + n FUN_001933-T1 146 KMDCSATGYPKPTVKWYKDNALYQERN 172 568**************8666655555 PP == domain 3 score: -1.6 bits; conditional E-value: 3.2 Ig_PDGFR_d4 2 kilelsd.shassgeqtvtCvaeGmPqPeveWf 33 kil++++ + ++ ++ t+ C a +P+ +W+ FUN_001933-T1 229 KILKMENaTAMEGENATLFCKALSDSMPHFQWL 261 677888745566677889999999999999996 PP == domain 4 score: 12.6 bits; conditional E-value: 0.00013 Ig_PDGFR_d4 17 tvtCvaeGmPqPeveWfiCkdikkCsnktsa 47 ++ C a+G+P+P+v+W+ + + + n +s+ FUN_001933-T1 375 KMDCSATGYPKPTVKWYKDNALYQVRNGSSK 405 568**************98888777776655 PP == domain 5 score: -1.6 bits; conditional E-value: 3.2 Ig_PDGFR_d4 2 kilelsd.shassgeqtvtCvaeGmPqPeveWf 33 kil++++ + ++ ++ t+ C a +P+ +W+ FUN_001933-T1 458 KILKMENaTAMEGENATLFCKALSDSMPHFQWL 490 677888745566677889999999999999996 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00052 0.56 53 114 .. 66 125 .. 40 139 .. 0.68 2 ? 3.6 0.0 0.075 80 37 92 .. 149 203 .. 140 214 .. 0.73 3 ? 2.4 0.0 0.18 1.9e+02 1 91 [. 238 329 .. 238 338 .. 0.76 4 ? 3.0 0.0 0.11 1.2e+02 37 92 .. 378 432 .. 366 442 .. 0.71 5 ? 2.0 0.0 0.24 2.5e+02 1 91 [. 467 558 .. 467 566 .. 0.75 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00052 Ig_6 53 kdgepleeikesspniileknaLrfkpvkvndsGlYiCrprirspqek.acclkiileVkpkk 114 k++e+l+ +++ + Lr+k v+++d+G+Y C +++ ++ + + ++e+ p+ FUN_001933-T1 66 KNNETLQPASHNRMR-VKPYRYLRIKNVTEEDAGFYACV--AKNSCGRnSLTWRLVIEIAPRF 125 344444444444433.355689****************9..4445544044568899988875 PP == domain 2 score: 3.6 bits; conditional E-value: 0.075 Ig_6 37 csgs.kdksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 cs + k +V+Wy+ + ++e +s+ n + +L ++ d GlY C++ FUN_001933-T1 149 CSATgYPKPTVKWYKD--NALYQERNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNV 203 5555455789****84..444445555556677788899999999999*******84 PP == domain 3 score: 2.4 bits; conditional E-value: 0.18 Ig_6 1 aiseeefvLfCdlpekqkshlynksqlsktqgselpcsgs..kdksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCr 91 a+++e+ LfC+ + + h+ + l++ + ++ s++ + ++ +q+ ++ l i + ++ +++ L + v +d G Y C FUN_001933-T1 238 AMEGENATLFCKALSDSMPHFQWLRWLAPPSNASDESSQIknPVYEVIKQNQQNGNKHSLLPIGKPA-QLDFHGVKLILTNVSKKDEGKYSCI 329 6788999999999999999998888877766665444444114455677777778888888888866.8999999999999999999999996 PP == domain 4 score: 3.0 bits; conditional E-value: 0.11 Ig_6 37 csgs.kdksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrp 92 cs + k +V+Wy+ + ++ + s+ n + +L ++ d GlY C++ FUN_001933-T1 378 CSATgYPKPTVKWYKDNALYQVRNGS--SKFNRGTFQTVLIIRNAVPADRGLYTCNV 432 5555456789****965544444433..3456666788999999999999***9984 PP == domain 5 score: 2.0 bits; conditional E-value: 0.24 Ig_6 1 aiseeefvLfCdlpekqkshlynksqlsktqgselpcsgs..kdksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCr 91 a+++e+ LfC+ + + h+ + l++ + ++ s++ + ++ +q+ ++ l i + ++ +++ L + v +d G Y C FUN_001933-T1 467 AMEGENATLFCKALSDSMPHFQWLRWLAPPSNASDESSQIknPVYEVIKQNQQNGNKHSLLPIGKPA-KLDFHGVKLILTNVSKKDEGKYSCI 558 6788999999999999999998888777766655444443114455667777777888888888866.8889999999999999999999996 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.8 0.0 0.0032 3.4 14 52 .. 58 107 .. 45 115 .. 0.73 2 ? 4.8 0.0 0.056 60 16 49 .. 160 205 .. 142 220 .. 0.57 3 ? 0.3 0.0 1.5 1.6e+03 31 48 .. 312 329 .. 301 345 .. 0.83 4 ? 4.4 0.0 0.077 82 31 49 .. 414 434 .. 371 449 .. 0.63 5 ? 0.4 0.0 1.3 1.4e+03 31 48 .. 541 558 .. 530 574 .. 0.82 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0032 Ig_4 14 e...itwlkdgkeikeskek........tldlgksiedprglYqCkeeek 52 + + w+k++++ + ++++ l++++++e++ g Y C +++ FUN_001933-T1 58 NkpiVFWVKNNETLQPASHNrmrvkpyrYLRIKNVTEEDAGFYACVAKNS 107 1344789999999888777767777887899**************85444 PP == domain 2 score: 4.8 bits; conditional E-value: 0.056 Ig_4 16 twlkdgkeikeskek..........tldlgksiedprglYqCk..e 49 +w+kd+ +e++ + l + + + +rglY+C+ + FUN_001933-T1 160 KWYKDNALYQERNGSskfnrgtfqtVLIIRNAVPADRGLYTCNvsN 205 555555544444433333333333345567777789******9532 PP == domain 3 score: 0.3 bits; conditional E-value: 1.5 Ig_4 31 tldlgksiedprglYqCk 48 +l l ++++ ++g Y+C FUN_001933-T1 312 KLILTNVSKKDEGKYSCI 329 67899999*********5 PP == domain 4 score: 4.4 bits; conditional E-value: 0.077 Ig_4 31 tldlgksiedprglYqCk..e 49 l + + + +rglY+C+ + FUN_001933-T1 414 VLIIRNAVPADRGLYTCNvsN 434 45566777789******9532 PP == domain 5 score: 0.4 bits; conditional E-value: 1.3 Ig_4 31 tldlgksiedprglYqCk 48 +l l ++++ ++g Y+C FUN_001933-T1 541 KLILTNVSKKDEGKYSCI 558 6789999**********6 PP >> Ig_C17orf99 C17orf99 Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 7.9e-06 0.0084 10 90 .. 37 118 .. 28 121 .. 0.85 2 ? -1.4 0.0 3.4 3.6e+03 15 34 .. 212 231 .. 202 256 .. 0.72 3 ? -0.3 0.0 1.5 1.6e+03 34 81 .. 282 335 .. 270 346 .. 0.66 4 ? -1.3 0.0 3.2 3.4e+03 68 82 .. 424 438 .. 367 451 .. 0.48 5 ? -1.4 0.0 3.4 3.6e+03 15 34 .. 441 460 .. 431 485 .. 0.72 6 ? 1.6 0.0 0.37 4e+02 33 84 .. 510 567 .. 498 574 .. 0.70 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 7.9e-06 Ig_C17orf99 10 levfpksrrvlisChasegsp..PItYsLvgkkgivvakkivkegkPAnFsllitlkssPdlltyaCqAantsgvqasslvLq 90 + +pk+r + + C +e+s+ PI++ +++ a + kP ++ l i + ++ d yaC+A+n+ g ++ + +L+ FUN_001933-T1 37 VTRVPKGRDARLICTVKETSRnkPIVFWVKNNETLQPASHNRMRVKPYRY-LRIKNVTEEDAGFYACVAKNSCGRNSLTWRLV 118 6678*************999555****99999988888877778889998.888999999**************998877776 PP == domain 2 score: -1.4 bits; conditional E-value: 3.4 Ig_C17orf99 15 ksrrvlisChasegspPItY 34 +s rv++ h + gs+P + FUN_001933-T1 212 NSYRVHVRNHERAGSKPKIL 231 56778888888888887554 PP == domain 3 score: -0.3 bits; conditional E-value: 1.5 Ig_C17orf99 34 YsLvgkkgivvakkivke.gkPAnFs.....llitlkssPdlltyaCqAantsg 81 Y+ ++++ + k+ + + gkPA+ l +t+ s+ d +y+C n g FUN_001933-T1 282 YEVIKQNQQNGNKHSLLPiGKPAQLDfhgvkLILTNVSKKDEGKYSCIVGNPFG 335 777777776666665543378998651122256888999999999998776655 PP == domain 4 score: -1.3 bits; conditional E-value: 3.2 Ig_C17orf99 68 dlltyaCqAantsgv 82 d y+C+ +n+ g FUN_001933-T1 424 DRGLYTCNVSNAYGW 438 444566666666555 PP == domain 5 score: -1.4 bits; conditional E-value: 3.4 Ig_C17orf99 15 ksrrvlisChasegspPItY 34 +s rv++ h + gs+P + FUN_001933-T1 441 NSYRVHVRNHERAGSKPKIL 460 56778888888888887554 PP == domain 6 score: 1.6 bits; conditional E-value: 0.37 Ig_C17orf99 33 tYsLvgkkgivvakkivke.gkPAnFs.....llitlkssPdlltyaCqAantsgvqa 84 +Y+ ++++ + k+ + + gkPA+ l +t+ s+ d +y+C n+ g + FUN_001933-T1 510 VYEVIKQNQQNGNKHSLLPiGKPAKLDfhgvkLILTNVSKKDEGKYSCIVGNAFGYAV 567 47777777777776665543899987611222568999999*******9999888655 PP >> Adeno_E3_CR1 Adenovirus E3 region protein CR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.18 1.9e+02 62 83 .. 87 108 .. 50 119 .. 0.79 2 ? 5.1 0.2 0.026 27 16 93 .. 147 219 .. 140 221 .. 0.72 3 ? 4.6 0.0 0.036 38 60 78 .. 311 329 .. 299 341 .. 0.89 4 ! 6.6 0.2 0.0087 9.3 16 93 .. 376 448 .. 369 450 .. 0.78 5 ? 5.0 0.0 0.029 30 60 78 .. 540 558 .. 527 573 .. 0.86 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.18 Adeno_E3_CR1 62 LtLlnvtktyeGtYygtnkkss 83 L + nvt+++ G+Y + k+s FUN_001933-T1 87 LRIKNVTEEDAGFYACVAKNSC 108 77889***********999875 PP == domain 2 score: 5.1 bits; conditional E-value: 0.026 Adeno_E3_CR1 16 snltLvGpsegkVtWykleedgdlkklCegekkkteeikvsCnkqnLtLlnvtktyeGtYygtnkks..sekedYkvkVl 93 +++ +G+++ V Wy +d+ l++ +g+ k + ++ L++ n+ ++ G Y + + +++Y+v+V FUN_001933-T1 147 MDCSATGYPKPTVKWY---KDNALYQERNGSSKFN----RGTFQTVLIIRNAVPADRGLYTCNVSNAygWISNSYRVHVR 219 578889**********...6666666656555554....44446679999999999999998755542256788888886 PP == domain 3 score: 4.6 bits; conditional E-value: 0.036 Adeno_E3_CR1 60 qnLtLlnvtktyeGtYygt 78 L+L+nv+k++eG Y + FUN_001933-T1 311 VKLILTNVSKKDEGKYSCI 329 679*************885 PP == domain 4 score: 6.6 bits; conditional E-value: 0.0087 Adeno_E3_CR1 16 snltLvGpsegkVtWykleedgdlkklCegekkkteeikvsCnkqnLtLlnvtktyeGtYygtnkks..sekedYkvkVl 93 +++ +G+++ V Wy +d+ l+++ +g+ k + ++ L++ n+ ++ G Y + + +++Y+v+V FUN_001933-T1 376 MDCSATGYPKPTVKWY---KDNALYQVRNGSSKFN----RGTFQTVLIIRNAVPADRGLYTCNVSNAygWISNSYRVHVR 448 578899**********...9999999999999886....33335679999999999999999755552266888999886 PP == domain 5 score: 5.0 bits; conditional E-value: 0.029 Adeno_E3_CR1 60 qnLtLlnvtktyeGtYygt 78 L+L+nv+k++eG Y + FUN_001933-T1 540 VKLILTNVSKKDEGKYSCI 558 679*************985 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.0031 3.3 13 79 .. 43 102 .. 36 107 .. 0.69 2 ? 5.1 0.0 0.039 42 19 83 .. 148 205 .. 140 207 .. 0.68 3 ? 3.9 0.0 0.088 94 19 83 .. 377 434 .. 369 436 .. 0.68 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.0031 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqllskLtvtpsewesgdeytC 79 g+ + L+C v++ + ++ V W+kn+++++ + + ++ + +y l +vt+ e y+C FUN_001933-T1 43 GRDARLICTVKETSRNKPIVFWVKNNETLQP--ASHNRMRVKPYRY--LRIKNVTE---EDAGFYAC 102 67899************************98..4444444433444..33334444...44555555 PP == domain 2 score: 5.1 bits; conditional E-value: 0.039 C1-set 19 vClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqllskLt.vtpsewesgdeytCkVeh 83 C++tg+ +V+W+k++ +e ++ +k + +t+q++ ++ p + ytC+V++ FUN_001933-T1 148 DCSATGYPK--PTVKWYKDNALYQE--RN-GSSKFNRGTFQTVLIIRnAVP---ADRGLYTCNVSN 205 588888744..4799******9998..33.333334577777665541444...688889999976 PP == domain 3 score: 3.9 bits; conditional E-value: 0.088 C1-set 19 vClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqllskLt.vtpsewesgdeytCkVeh 83 C++tg+ +V+W+k++ + v++ + +n +t+q++ ++ p + ytC+V++ FUN_001933-T1 377 DCSATGYPK--PTVKWYKDNALYQ--VRNGSSKFN-RGTFQTVLIIRnAVP---ADRGLYTCNVSN 434 588888744..4799****99888..566665555.567776655541445...788889999976 PP >> FixG_C IG-like fold at C-terminal of FixG, putative oxidoreductase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 3.4 3.6e+03 91 106 .. 55 69 .. 26 78 .. 0.66 2 ! 8.8 0.0 0.0022 2.4 24 45 .. 203 224 .. 189 240 .. 0.81 3 ! 8.8 0.0 0.0022 2.4 24 45 .. 432 453 .. 418 469 .. 0.81 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 3.4 FixG_C 91 kkgsteiefeveddde 106 ++++++i+f+v+ ++e FUN_001933-T1 55 TSRNKPIVFWVK-NNE 69 345679999997.332 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0022 FixG_C 24 velsdgsieNvYtlkilNktee 45 v ++ g+i+N+Y+++++N+++ FUN_001933-T1 203 VSNAYGWISNSYRVHVRNHERA 224 5677799***********9875 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0022 FixG_C 24 velsdgsieNvYtlkilNktee 45 v ++ g+i+N+Y+++++N+++ FUN_001933-T1 432 VSNAYGWISNSYRVHVRNHERA 453 5677799***********9875 PP >> Receptor_2B4 Natural killer cell receptor 2B4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.4 1.5e+03 72 95 .. 86 109 .. 51 118 .. 0.68 2 ! 7.8 0.0 0.005 5.3 45 99 .. 158 212 .. 145 218 .. 0.87 3 ? -2.1 0.0 6 6.3e+03 66 95 .. 306 335 .. 271 344 .. 0.62 4 ! 7.1 0.0 0.0081 8.6 45 99 .. 387 441 .. 374 447 .. 0.85 5 ? -1.2 0.0 3.1 3.3e+03 66 99 .. 535 568 .. 500 574 .. 0.68 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.4 Receptor_2B4 72 alsiksaklqdsGlylleitnisG 95 l ik +d+G+y n G FUN_001933-T1 86 YLRIKNVTEEDAGFYACVAKNSCG 109 3889***********876666665 PP == domain 2 score: 7.8 bits; conditional E-value: 0.005 Receptor_2B4 45 ilkwendslkssnvsssdiygfevknlalsiksaklqdsGlylleitnisGkvct 99 +kw++d+ ++ s ++ + + l i+ a d Gly +++n G + + FUN_001933-T1 158 TVKWYKDNALYQERNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNAYGWISN 212 589**99999999888888888888899*********************998876 PP == domain 3 score: -2.1 bits; conditional E-value: 6 Receptor_2B4 66 fevknlalsiksaklqdsGlylleitnisG 95 ++ + + l + ++d G+y + n G FUN_001933-T1 306 LDFHGVKLILTNVSKKDEGKYSCIVGNPFG 335 445555666666677777777766666555 PP == domain 4 score: 7.1 bits; conditional E-value: 0.0081 Receptor_2B4 45 ilkwendslkssnvsssdiygfevknlalsiksaklqdsGlylleitnisGkvct 99 +kw++d+ + s ++ + + l i+ a d Gly +++n G + + FUN_001933-T1 387 TVKWYKDNALYQVRNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNAYGWISN 441 5899999988888778888888888889*********************998876 PP == domain 5 score: -1.2 bits; conditional E-value: 3.1 Receptor_2B4 66 fevknlalsiksaklqdsGlylleitnisGkvct 99 ++ + + l + ++d G+y + n G + FUN_001933-T1 535 LDFHGVKLILTNVSKKDEGKYSCIVGNAFGYAVQ 568 5555666777778888889988888887776554 PP >> Dynein_light Dynein light chain type 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.0 0.005 5.4 38 65 .. 312 339 .. 269 342 .. 0.80 2 ! 9.4 0.0 0.0018 1.9 38 65 .. 541 568 .. 498 571 .. 0.80 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.005 Dynein_light 38 ahiKkefdkkygptWhvivGknFgsyvt 65 + i ++ kk ++ + +ivG+ Fg+ v FUN_001933-T1 312 KLILTNVSKKDEGKYSCIVGNPFGYAVQ 339 5667788999**************9885 PP == domain 2 score: 9.4 bits; conditional E-value: 0.0018 Dynein_light 38 ahiKkefdkkygptWhvivGknFgsyvt 65 + i ++ kk ++ + +ivG+ Fg+ v FUN_001933-T1 541 KLILTNVSKKDEGKYSCIVGNAFGYAVQ 568 5667788999**************9885 PP >> Pox_vIL-18BP Orthopoxvirus interleukin 18 binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.0 0.0038 4.1 35 79 .. 244 289 .. 229 331 .. 0.84 2 ! 8.3 0.0 0.0034 3.7 35 79 .. 473 518 .. 458 569 .. 0.83 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0038 Pox_vIL-18BP 35 gefrcsgcvkfmpkfsymywlakd.mksdedakfiehlgegikede 79 ++c + mp+f ++ wla sde +++ + + e ik+++ FUN_001933-T1 244 ATLFCKALSDSMPHFQWLRWLAPPsNASDESSQIKNPVYEVIKQNQ 289 457899999*************861568999988888888888765 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0034 Pox_vIL-18BP 35 gefrcsgcvkfmpkfsymywlakd.mksdedakfiehlgegikede 79 ++c + mp+f ++ wla sde +++ + + e ik+++ FUN_001933-T1 473 ATLFCKALSDSMPHFQWLRWLAPPsNASDESSQIKNPVYEVIKQNQ 518 457899999*************861568999998888888888765 PP >> Izumo-Ig Izumo-like Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.1 1.1e+02 50 68 .. 86 104 .. 62 117 .. 0.80 2 ? -1.7 0.0 3.9 4.2e+03 52 69 .. 187 204 .. 179 218 .. 0.76 3 ? 4.1 0.0 0.06 64 50 70 .. 312 332 .. 307 352 .. 0.81 4 ? -1.2 0.0 2.7 2.9e+03 50 69 .. 414 433 .. 393 447 .. 0.75 5 ? 4.4 0.0 0.046 49 50 71 .. 541 562 .. 536 578 .. 0.80 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.1 Izumo-Ig 50 tLtkpmvgledaGtYRCeL 68 +L + v+ edaG Y C FUN_001933-T1 86 YLRIKNVTEEDAGFYACVA 104 5667789**********75 PP == domain 2 score: -1.7 bits; conditional E-value: 3.9 Izumo-Ig 52 tkpmvgledaGtYRCeLd 69 + + d G Y C++ FUN_001933-T1 187 IIRNAVPADRGLYTCNVS 204 4445567899*****876 PP == domain 3 score: 4.1 bits; conditional E-value: 0.06 Izumo-Ig 50 tLtkpmvgledaGtYRCeLdt 70 L+++ v+ +d+G+Y C +++ FUN_001933-T1 312 KLILTNVSKKDEGKYSCIVGN 332 588999***********9876 PP == domain 4 score: -1.2 bits; conditional E-value: 2.7 Izumo-Ig 50 tLtkpmvgledaGtYRCeLd 69 +L+ + d G Y C++ FUN_001933-T1 414 VLIIRNAVPADRGLYTCNVS 433 455555668899*****876 PP == domain 5 score: 4.4 bits; conditional E-value: 0.046 Izumo-Ig 50 tLtkpmvgledaGtYRCeLdtv 71 L+++ v+ +d+G+Y C +++ FUN_001933-T1 541 KLILTNVSKKDEGKYSCIVGNA 562 588999***********99865 PP >> Lep_receptor_Ig Ig-like C2-type domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.1 0.00064 0.68 9 85 .. 36 108 .. 34 117 .. 0.83 2 ? 0.4 0.0 0.86 9.1e+02 22 66 .. 101 139 .. 86 146 .. 0.73 3 ? 1.2 0.0 0.47 5e+02 24 65 .. 144 185 .. 141 207 .. 0.72 4 ? -0.7 0.0 1.9 2e+03 25 65 .. 374 414 .. 372 435 .. 0.70 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00064 Lep_receptor_Ig 9 espvvrlGsnvtasCilkenCesklgseaqivlWklkae.lipkeqysklndtvssvtlpnlnstkalLtCclewgns 85 e v+ G +C++ke ++ ++ iv+W ++e l+p ++ + + ++++n+++ a ++ c++ +++ FUN_001933-T1 36 EVTRVPKGRDARLICTVKE-----TSRNKPIVFWVKNNEtLQPASHNRMRVKPYRYLRIKNVTEEDAGFYACVAKNSC 108 55668889999999****9.....459999****88888799**9999999999999999999999988877776666 PP == domain 2 score: 0.4 bits; conditional E-value: 0.86 Lep_receptor_Ig 22 sCilkenCesklgseaqivlWklkaelipkeqysklndtvssvtl 66 C+ k++C ++++ W+l e+ p+ + s+ ++ + l FUN_001933-T1 101 ACVAKNSC-----GRNSLT-WRLVIEIAPRFTVSEKRRRRNGIVL 139 69999999.....445555.9999999888888777777666655 PP == domain 3 score: 1.2 bits; conditional E-value: 0.47 Lep_receptor_Ig 24 ilkenCesklgseaqivlWklkaelipkeqysklndtvssvt 65 ++k +C+ ++ ++ ++k +a ++++ sk+n+++++ FUN_001933-T1 144 TIKMDCSATGYPKPTVKWYKDNALYQERNGSSKFNRGTFQTV 185 5788996666777777777777779***********994433 PP == domain 4 score: -0.7 bits; conditional E-value: 1.9 Lep_receptor_Ig 25 lkenCesklgseaqivlWklkaelipkeqysklndtvssvt 65 +k +C+ ++ ++ ++k +a + ++ sk+n+++++ FUN_001933-T1 374 IKMDCSATGYPKPTVKWYKDNALYQVRNGSSKFNRGTFQTV 414 78899666667777777777777999999999999994333 PP >> Ig_VEGFR-1-like_5th VEGFR-1-like, immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.47 5e+02 100 120 .. 93 113 .. 77 123 .. 0.79 2 ? 2.6 0.0 0.19 2.1e+02 25 44 .. 145 164 .. 139 177 .. 0.88 3 ? -2.5 0.0 7.3 7.8e+03 102 117 .. 194 209 .. 169 221 .. 0.61 4 ? 2.5 0.0 0.21 2.2e+02 24 78 .. 243 295 .. 226 347 .. 0.63 5 ? 2.4 0.0 0.22 2.3e+02 25 43 .. 374 392 .. 368 399 .. 0.88 6 ? -2.5 0.0 7.1 7.5e+03 97 117 .. 416 438 .. 397 450 .. 0.61 7 ? 3.2 0.0 0.13 1.3e+02 24 117 .. 472 565 .. 455 578 .. 0.62 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.47 Ig_VEGFR-1-like_5th 100 tanvsgvysctarnelgnrtm 120 t + +g y+c a+n g ++ FUN_001933-T1 93 TEEDAGFYACVAKNSCGRNSL 113 456689*********998765 PP == domain 2 score: 2.6 bits; conditional E-value: 0.19 Ig_VEGFR-1-like_5th 25 hkltctafgipmpnitwfwq 44 k+ c+a g p p + w+ + FUN_001933-T1 145 IKMDCSATGYPKPTVKWYKD 164 5899*************965 PP == domain 3 score: -2.5 bits; conditional E-value: 7.3 Ig_VEGFR-1-like_5th 102 nvsgvysctarnelgn 117 g+y+c n g FUN_001933-T1 194 ADRGLYTCNVSNAYGW 209 2358999998888775 PP == domain 4 score: 2.5 bits; conditional E-value: 0.21 Ig_VEGFR-1-like_5th 24 rhkltctafgipmpnitwfwqpcdpsanltecklytdplpienvddhfpqnpikd 78 l c a+ mp w+ + ps e +p+ +v + qn k FUN_001933-T1 243 NATLFCKALSDSMPHFQWLRWLAPPSNASDESSQIKNPV--YEVIKQNQQNGNKH 295 56789*************988888888877777666654..44444455555554 PP == domain 5 score: 2.4 bits; conditional E-value: 0.22 Ig_VEGFR-1-like_5th 25 hkltctafgipmpnitwfw 43 k+ c+a g p p + w+ FUN_001933-T1 374 IKMDCSATGYPKPTVKWYK 392 5899*************96 PP == domain 6 score: -2.5 bits; conditional E-value: 7.1 Ig_VEGFR-1-like_5th 97 vvkta..nvsgvysctarnelgn 117 +++ a g+y+c n g FUN_001933-T1 416 IIRNAvpADRGLYTCNVSNAYGW 438 34433112358999998888775 PP == domain 7 score: 3.2 bits; conditional E-value: 0.13 Ig_VEGFR-1-like_5th 24 rhkltctafgipmpnitwfwqpcdpsanltecklytdplpienvddhfpqnpikdvnskvgll.kskn...rtistlvvktanvsgvysc 109 l c a+ mp w+ + ps e +p + +v + qn k +g k + i t v k + g ysc FUN_001933-T1 472 NATLFCKALSDSMPHFQWLRWLAPPSNASDESSQIKNP--VYEVIKQNQQNGNKHSLLPIGKPaKLDFhgvKLILTNVSK--KDEGKYSC 557 56789*************98888888888888777665..4455556666666655544443202222000222222222..23477777 PP Ig_VEGFR-1-like_5th 110 tarnelgn 117 n +g FUN_001933-T1 558 IVGNAFGY 565 77777665 PP >> DUF4960 Domain of unknown function (DUF4960) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.0 0.0058 6.2 173 225 .. 160 212 .. 126 224 .. 0.84 2 ? 6.5 0.0 0.0087 9.3 173 225 .. 389 441 .. 359 453 .. 0.84 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0058 DUF4960 173 gdyedkdafeaktGgkalastgdnavvifelkkrsnkGrticiGsglydWysk 225 y+d++ ++ + G+ ++ +++ ++v i+ +++G c s++y W s+ FUN_001933-T1 160 KWYKDNALYQERNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNAYGWISN 212 45999999************999******999999***************985 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0087 DUF4960 173 gdyedkdafeaktGgkalastgdnavvifelkkrsnkGrticiGsglydWysk 225 y+d++ ++ + G+ ++ +++ ++v i+ +++G c s++y W s+ FUN_001933-T1 389 KWYKDNALYQVRNGSSKFNRGTFQTVLIIRNAVPADRGLYTCNVSNAYGWISN 441 45999999************999******999999***************985 PP >> BARF1_ig2 BARF1 second Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.045 48 15 40 .. 138 163 .. 123 175 .. 0.83 2 ? -1.5 0.0 3.3 3.5e+03 23 40 .. 245 262 .. 227 279 .. 0.74 3 ? 4.6 0.0 0.042 45 15 40 .. 367 392 .. 353 409 .. 0.84 4 ? -1.4 0.0 3.2 3.4e+03 23 40 .. 474 491 .. 456 510 .. 0.74 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.045 BARF1_ig2 15 vypdfsvltvrckvnayphphvewlm 40 v p ++++ c yp+p v+w FUN_001933-T1 138 VLPVGNTIKMDCSATGYPKPTVKWYK 163 5677789999**************75 PP == domain 2 score: -1.5 bits; conditional E-value: 3.3 BARF1_ig2 23 tvrckvnayphphvewlm 40 t+ ck + ph +wl FUN_001933-T1 245 TLFCKALSDSMPHFQWLR 262 455777777778888874 PP == domain 3 score: 4.6 bits; conditional E-value: 0.042 BARF1_ig2 15 vypdfsvltvrckvnayphphvewlm 40 v p ++++ c yp+p v+w FUN_001933-T1 367 VLPVGNTIKMDCSATGYPKPTVKWYK 392 5677789999**************86 PP == domain 4 score: -1.4 bits; conditional E-value: 3.2 BARF1_ig2 23 tvrckvnayphphvewlm 40 t+ ck + ph +wl FUN_001933-T1 474 TLFCKALSDSMPHFQWLR 491 455777777778888874 PP >> Syndecan Syndecan domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.046 49 29 43 .. 313 327 .. 310 334 .. 0.84 2 ? 4.4 0.0 0.05 53 29 43 .. 542 556 .. 539 560 .. 0.83 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.046 Syndecan 29 llvYrmrKKDEGsYa 43 l++ + KKDEG Y+ FUN_001933-T1 313 LILTNVSKKDEGKYS 327 6777789*******6 PP == domain 2 score: 4.4 bits; conditional E-value: 0.05 Syndecan 29 llvYrmrKKDEGsYa 43 l++ + KKDEG Y+ FUN_001933-T1 542 LILTNVSKKDEGKYS 556 6777789*******6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (591 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 387 (0.0151497); expected 510.9 (0.02) Passed bias filter: 352 (0.0137796); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 24 (0.000939518); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 24 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 5983.77 // Query: FUN_001934-T1 [L=104] Description: FUN_001934 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00012 22.8 0.0 0.00025 21.8 0.0 1.5 1 Helicase_C Helicase conserved C-terminal domain ------ inclusion threshold ------ 0.15 13.0 1.1 0.21 12.5 1.1 1.1 1 FERM_C FERM C-terminal PH-like domain Domain annotation for each model (and alignments): >> Helicase_C Helicase conserved C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 1.9e-08 0.00025 77 110 .] 1 34 [. 1 34 [. 0.97 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 1.9e-08 Helicase_C 77 rGldlpdvdlvinydlpwnpasyiQriGRagRag 110 +G++ pd + vi++ p ++ +y Q +GR+gR g FUN_001934-T1 1 MGINCPDMSQVIHLRSPCSLLNYAQESGRCGRDG 34 6*******************************76 PP >> FERM_C FERM C-terminal PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 1.1 1.6e-05 0.21 34 92 .. 37 98 .. 36 99 .. 0.89 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.6e-05 FERM_C 34 eirkisfkrkkfliklr...keedkkkeetleFklessrackslwklcveqhkffrlrkssk 92 ++k+++++++f i ++ ++ +k+++e+ k++s+ ++ks ++l + +h f +k+ + FUN_001934-T1 37 AVAKLYYSNREFGICSSksnRKTTKYQSEICDLKMKSYVSNKSECHLLLLSHYFVLMEKQMQ 98 589***********888666788899999*************************99888766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 966 (0.0378156); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1057.95 // Query: FUN_001935-T1 [L=141] Description: FUN_001935 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.066 14.0 2.3 0.29 12.0 0.4 2.6 3 MbeB_N MbeB-like, N-term conserved region Domain annotation for each model (and alignments): >> MbeB_N MbeB-like, N-term conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 0.12 3.2e+03 41 45 .. 16 20 .. 9 49 .. 0.60 2 ? 12.0 0.4 1.1e-05 0.29 19 36 .. 63 80 .. 52 86 .. 0.83 3 ? -0.0 0.0 0.062 1.6e+03 26 43 .. 95 112 .. 93 115 .. 0.81 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.12 MbeB_N 41 Lkese 45 L+ s FUN_001935-T1 16 LEASK 20 44443 PP == domain 2 score: 12.0 bits; conditional E-value: 1.1e-05 MbeB_N 19 aeSteemvksafekheks 36 +S+eem k +f++h k+ FUN_001935-T1 63 TKSMEEMSKEEFKEHKKN 80 69**************98 PP == domain 3 score: -0.0 bits; conditional E-value: 0.062 MbeB_N 26 vksafekheksvkeaLke 43 +k+ +k++++ ++a++e FUN_001935-T1 95 IKAKVKKLRSNFQKAVAE 112 688899999999988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (141 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1653 (0.0647093); expected 510.9 (0.02) Passed bias filter: 770 (0.0301429); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1387.20 // Query: FUN_001937-T1 [L=119] Description: FUN_001937 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-08 32.7 0.1 1.2e-07 32.2 0.1 1.2 1 Trypsin Trypsin ------ inclusion threshold ------ 0.11 13.4 0.0 0.18 12.7 0.0 1.3 1 DUF1986 Domain of unknown function (DUF1986) Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.2 0.1 9.5e-12 1.2e-07 1 38 [. 65 102 .. 65 103 .. 0.97 Alignments for each domain: == domain 1 score: 32.2 bits; conditional E-value: 9.5e-12 Trypsin 1 ivggeeaqagsfpwqvslqlssgkhfCGGslisenwvl 38 iv+ ++a++g++pwq+ +++++g++fCGG+li ++wvl FUN_001937-T1 65 IVNASKATKGEWPWQAIVAFKGGGQFCGGTLIAKKWVL 102 79999********************************8 PP >> DUF1986 Domain of unknown function (DUF1986) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 1.4e-05 0.18 1 26 [. 76 102 .. 76 108 .. 0.87 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.4e-05 DUF1986 1 wPwladvyle.GdlicsGvlidkswvl 26 wPw a v ++ G +c G li k+wvl FUN_001937-T1 76 WPWQAIVAFKgGGQFCGGTLIAKKWVL 102 9****9987625789***********8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 293 (0.01147); expected 510.9 (0.02) Passed bias filter: 258 (0.0100998); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1190.66 // Query: FUN_001938-T1 [L=83] Description: FUN_001938 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-08 35.3 0.0 1.4e-08 35.3 0.0 1.1 1 Trypsin Trypsin Domain annotation for each model (and alignments): >> Trypsin Trypsin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.3 0.0 5.7e-13 1.4e-08 64 119 .. 11 70 .. 1 80 [. 0.78 Alignments for each domain: == domain 1 score: 35.3 bits; conditional E-value: 5.7e-13 Trypsin 64 gseqklkvekvivhpnynsdt.ldnDiallklkspvtlgdavrpiclpa....assslavg 119 q++ v++ + hpnyn++ l nDi+ll+lk+++++g v+++clp+ + ++l++g FUN_001938-T1 11 I-RQEIRVAETVAHPNYNDPVrLANDIMLLRLKTEAKIGAEVETVCLPDtiheNYATLQAG 70 3.47899***********99978**************************665444444555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (83 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 332 (0.0129967); expected 510.9 (0.02) Passed bias filter: 295 (0.0115482); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.22u 0.41s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 857.43 // Query: FUN_001939-T1 [L=160] Description: FUN_001939 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 560 (0.0219221); expected 510.9 (0.02) Passed bias filter: 484 (0.018947); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.43s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1610.13 // Query: FUN_001940-T1 [L=752] Description: FUN_001940 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-162 541.6 28.8 1.9e-162 541.6 28.8 2.4 2 BCCT BCCT, betaine/carnitine/choline family trans 3.1e-10 41.4 3.6 4e-09 37.8 0.0 3.1 3 PLAC8 PLAC8 family ------ inclusion threshold ------ 1.4 9.4 4.6 3.9 8.0 4.6 1.7 1 Enterotoxin_HS1 Heat stable E.coli enterotoxin 1 Domain annotation for each model (and alignments): >> BCCT BCCT, betaine/carnitine/choline family transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 541.6 28.8 2.2e-166 1.9e-162 1 483 [. 44 563 .. 44 565 .. 0.91 2 ? -2.1 0.8 0.16 1.3e+03 78 99 .. 632 655 .. 629 689 .. 0.81 Alignments for each domain: == domain 1 score: 541.6 bits; conditional E-value: 2.2e-166 BCCT 1 vflvslllillfvllglifpeeleevlntalewilekfgwlylllvllflvfvlvlafskygkikLGkddekpefstfsWlamlfaagmgiglvfw 96 v +vs+l+i+ fv++++i pe++++ + ++ wi+++f+w+y+ + ++ vf++vl fskyg++kLGk+dekpef+ s+++mlfaag+gigl+++ FUN_001940-T1 44 VSFVSALIIWGFVAWCMIEPEAANKQMGIWKLWITRTFTWMYIGTQDAWTVFIIVLYFSKYGEMKLGKPDEKPEFKDASYFTMLFAAGIGIGLFYF 139 6799******************************************************************************************** PP BCCT 97 gvaEplshyaspppga....eagteeaaeeAlaltffhwGlhawaiyalvalalayfayrkglplkissalypllgeriegliGkviDilaviatv 188 g+aEp++hy +g+ + +++a+ ++++t+fhwG+h+w +y++v+l la+++yr+glp++++s++ypl+g++i+g++G++iDi++v++t+ FUN_001940-T1 140 GIAEPIWHYEPGHYGNryfnRYSDNQRAQDSITITLFHWGIHGWVVYVVVGLLLAFVCYRQGLPMTMRSCMYPLIGDKIYGWMGDAIDIVSVVCTM 235 *********9987666666345555666******************************************************************** PP BCCT 189 fGvatsLGlgvlqinaglself.giensltvqlliiavitavalisavsGldkGikvlSnlnvllavllllfvlivGptlfilnlfveslgdylqn 283 fGv+tsLGlgv+q+nag+++l +ie s++ q++ii+++ta+a++s++sGl+ Gi++lS++ ++l v+++l+v+++++ + lnl+v+s+g+ylqn FUN_001940-T1 236 FGVCTSLGLGVMQLNAGVHRLRdSIEISTLNQIIIIWCVTACATVSVISGLKMGIRRLSEICFALGVFIMLLVFFLDDPGHSLNLIVQSTGHYLQN 331 **********************679*********************************************************************** PP BCCT 284 lvelslrtdaleees.........ewlesWTiFywaWwiawapfvglFiAriSrGRtirefilgvllvptlvtllwftvfGgtalelelegegela 370 +++l ++tda+++ + +w+++WTiFyw+Wwiaw+pfvg+FiA+iSrGRtir+fi ++l +p+++++lwf +fGg++l++e++ + + + FUN_001940-T1 332 VIQLGFHTDAFAQVGnapdgkeaqNWMNEWTIFYWGWWIAWSPFVGMFIAKISRGRTIRQFINATLTAPVAFSILWFGIFGGAGLRMERNAALQNI 427 **********995545556677779************************************************************99987665444 PP BCCT 371 k..................a.aeaeveaalfalleql.plgtilsvlallliiiffvTsaDSatlvlamlsskgdeepsrllrvfWgvllgavaav 446 + ++ + + f+++eq+ lg +lsvl l+ i+++fvTs+DS++lv++ ls++gd +p+ l+rvfW++++ga+a++ FUN_001940-T1 428 TcssplggknateslnglyRlSCRGKNDMWFDVMEQYdELGPVLSVLSLMGIVLYFVTSSDSGSLVIDCLSANGDPKPPVLQRVFWALTEGATATA 523 422222222222222222111333444455555555599********************************************************* PP BCCT 447 lllagg...lealqsasiiaalPfslilllmvvsllkalk 483 ll++gg l+alq++s++ ++P +++l++m+v+l++a+k FUN_001940-T1 524 LLYVGGneaLTALQTVSVASGVPYTVMLCFMCVALWRAVK 563 ****9999*****************************987 PP == domain 2 score: -2.1 bits; conditional E-value: 0.16 BCCT 78 fsWlamlfaagm..giglvfwgva 99 ++W+++l+ g+ gig+v w+v FUN_001940-T1 632 YTWISLLVLGGLvsGIGIVGWSVL 655 689999998886559999999986 PP >> PLAC8 PLAC8 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 1.5 0.054 4.6e+02 50 96 .. 236 280 .. 171 292 .. 0.65 2 ? -4.2 0.2 3 2.6e+04 89 93 .. 551 555 .. 533 561 .. 0.55 3 ! 37.8 0.0 4.7e-13 4e-09 1 100 [. 576 699 .. 576 700 .. 0.77 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.054 PLAC8 50 lllllllglalilscllRsklRekygiegspceDclvhlcCecCalc 96 +++ l+l ++ l+ + R + +ie s+++ +++ +c + Ca + FUN_001940-T1 236 F--GVCTSLGLGVMQLNAGVHRLRDSIEISTLNQIIIIWCVTACATV 280 1..11222222233344555555555666889999999999999875 PP == domain 2 score: -4.2 bits; conditional E-value: 3 PLAC8 89 cCecC 93 +C +C FUN_001940-T1 551 LCFMC 555 12111 PP == domain 3 score: 37.8 bits; conditional E-value: 4.7e-13 PLAC8 1 Wstglfdc.....fsdlelclltlfcpcvlfgrnaerldkgntscllalv.......lvllll.............lllllglali.......... 61 ++tgl+d+ ++ ++ +ll++f+p++ +g +a l++ n+ +++++ + + i FUN_001940-T1 576 FTTGLLDVlsaptTESVSKVLLSIFAPWYCMGVAAGELERPNGRKWTHMLilaipfyT----WisllvlgglvsgiG--------Ivgwsvlfgff 659 6899999977777778888********************9999888887766645320....133445555544331........02333455666 PP PLAC8 62 .lscllRsklRekygiegspceDclvhlcCecCalcQeer 100 +++ +R ++Rekygi+g++ eD++++ ++ + a Q+e FUN_001940-T1 660 aYATGIRISIREKYGISGNMTEDFFAVAMLFPFAAFQMEH 699 6899*********************************986 PP >> Enterotoxin_HS1 Heat stable E.coli enterotoxin 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 4.6 0.00045 3.9 16 24 .. 271 279 .. 269 281 .. 0.89 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00045 Enterotoxin_HS1 16 IWCvTACaS 24 IWCvTACa FUN_001940-T1 271 IWCVTACAT 279 9******96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (752 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 879 (0.0344099); expected 510.9 (0.02) Passed bias filter: 423 (0.016559); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.40u 0.38s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7261.05 // Query: FUN_001941-T1 [L=1107] Description: FUN_001941 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-13 48.3 10.3 0.0081 16.3 0.0 4.6 4 IQ IQ calmodulin-binding motif 0.0054 17.6 6.0 0.012 16.5 0.1 3.5 2 NPHP4_SK Nephrocystin-4 SK-like domain ------ inclusion threshold ------ 0.014 15.9 10.7 0.014 15.9 10.7 4.2 4 KASH_CCD Coiled-coil region of CCDC155 or KASH 0.46 10.0 5.4 8.7 5.8 2.5 2.6 2 Seadorna_VP6 Seadornavirus VP6 protein Domain annotation for each model (and alignments): >> IQ IQ calmodulin-binding motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.9 1.3 1.7e-05 0.11 2 19 .. 530 547 .. 529 547 .. 0.93 2 ! 10.4 0.0 0.0001 0.66 2 17 .. 563 578 .. 562 581 .. 0.89 3 ! 12.0 0.1 3.3e-05 0.21 2 20 .. 589 607 .. 588 608 .. 0.93 4 ! 16.3 0.0 1.3e-06 0.0081 2 20 .. 622 640 .. 621 641 .. 0.93 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 1.7e-05 IQ 2 kaaikIQaawRGylaRkr 19 +aa ++Q+ wRGy+ Rk+ FUN_001941-T1 530 RAAKTLQREWRGYQGRKQ 547 8*************9996 PP == domain 2 score: 10.4 bits; conditional E-value: 0.0001 IQ 2 kaaikIQaawRGylaR 17 +aa ++Q+ wR+++ R FUN_001941-T1 563 EAAATLQKNWRRHRER 578 69***********988 PP == domain 3 score: 12.0 bits; conditional E-value: 3.3e-05 IQ 2 kaaikIQaawRGylaRkry 20 +a++ IQaa RG +R +y FUN_001941-T1 589 EAITAIQAALRGQAVRSKY 607 79***************99 PP == domain 4 score: 16.3 bits; conditional E-value: 1.3e-06 IQ 2 kaaikIQaawRGylaRkry 20 +a++ IQ+a R++l Rk++ FUN_001941-T1 622 DAIVAIQSAMRAHLSRKKH 640 79***************96 PP >> NPHP4_SK Nephrocystin-4 SK-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.1 1.8e-06 0.012 27 59 .. 108 140 .. 102 148 .. 0.84 2 ? 0.1 2.7 0.24 1.5e+03 8 36 .. 573 601 .. 545 612 .. 0.84 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 1.8e-06 NPHP4_SK 27 grrkasvlaqqsvraqhsRDLQvidAYRERtKA 59 +r +s la+ r+qh+RDL vid + R FUN_001941-T1 108 SRATTSKLAKSGSRTQHFRDLVVIDNLKSRNHV 140 5678999******************99888765 PP == domain 2 score: 0.1 bits; conditional E-value: 0.24 NPHP4_SK 8 rRKLeRmrsVRlqEakgelgrrkasvlaq 36 rR eR + + +E ++++ +a++++q FUN_001941-T1 573 RRHRERAKEIEVKEKEEAITAIQAALRGQ 601 78889999999999999999999997766 PP >> KASH_CCD Coiled-coil region of CCDC155 or KASH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 10.7 2.1e-06 0.014 67 187 .. 167 285 .. 151 290 .. 0.90 2 ? -5.4 15.6 4 2.6e+04 37 185 .. 323 472 .. 314 478 .. 0.47 3 ? -3.2 11.7 1.6 1e+04 10 78 .. 426 494 .. 422 553 .. 0.77 4 ? -8.0 9.3 4 2.6e+04 86 145 .. 549 608 .. 516 633 .. 0.53 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.1e-06 KASH_CCD 67 eEledlktlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaaerdllkkklkeLleekaeLkkqlyeleellasreelleektkqiee 162 +E+ +lk++++ l+ +++ + ++ +++e en k+e+L ++ ++ r +l k+ + + + Lk++l+ +e + ++e++l++ k FUN_001941-T1 167 DEVIELKKVINALKAENNIISTKLRRVEGENILKDRKMEDLLNQRKQPEDVRRTLTDKKGDTSAIVNSLKQKLHGVERTVKDKETELSQLKK---T 259 7999**************************************9999999999999999999999999********************98655...4 PP KASH_CCD 163 Lkst.veEyssvteeLraeisrLeeq 187 Lk+t +eE++ e + ei+rL+ + FUN_001941-T1 260 LKMTnIEELQIQSETYYQEIQRLQLV 285 5554388999999999*******965 PP == domain 2 score: -5.4 bits; conditional E-value: 4 KASH_CCD 37 tnakLteEieeLkkklkstQqalq..kakllkeEledlk..tlvksleEraaslqaqnkqlekenqsLeakiesLqeeneklaaerdllkkklkeL 128 +n +L +E+ Lkk l s ++ ++ lk + +d+ +l+ + E ++++ + ek + sL ++ +ee ek+ r+ ++ ++L FUN_001941-T1 323 ENDHLKAENRGLKKDLLSAIETSAggSKVPLKADYADMSrgQLLATIHELEEKILKPGE--EKRKGSLYEED---KEEGEKS--RRSSSASSVAKL 411 56666666666666665554443311233356666666422355555555555554433..55555665542...2333332..234444555555 PP KASH_CCD 129 leekaeLkkqlyeleellasre.elleektkq...ieeLkstveEyssvteeLraeisrLe 185 +e + +Lk + + l +re ellee+ kq ie Lk + y++v ++Lr++ + FUN_001941-T1 412 TEGRVQLKGSTSQKLAQLQEREmELLEEREKQrevIERLKEDRAHYRLVADDLRMQLHFTQ 472 5555555555443333334444133444443322345566666666666666665554444 PP == domain 3 score: -3.2 bits; conditional E-value: 1.6 KASH_CCD 10 vedLqlnNkkLaeensklqkavetaeetnakLteEieeLkkklkstQqalqkakllkeEledlktlvks 78 ++ Lq L ee k ++ +e e a+ +L+ +l+ tQ l + k +e+ +++ + FUN_001941-T1 426 LAQLQEREMELLEEREKQREVIERLKEDRAHYRLVADDLRMQLHFTQEELDTLRGEKGSVENKRRSSTA 494 678888888899999999999999999999888888899999999999888888888888777776554 PP == domain 4 score: -8.0 bits; conditional E-value: 4 KASH_CCD 86 lqaqnkqlekenqsLe.akiesLqeenekla..aerdllkkklkeLleekaeLkkqlyeleel 145 + e+e++ + + ++Lq++ ++ + a ++k+k + +++ +a L+ q + + FUN_001941-T1 549 VME---EKEREEENRQnEAAATLQKNWRRHRerAKEIEVKEKEEAITAIQAALRGQAVRSKYI 608 222...223444333303345566544443300222346777777888888888876555544 PP >> Seadorna_VP6 Seadornavirus VP6 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 2.5 0.0014 8.7 6 63 .. 164 221 .. 160 295 .. 0.82 2 ? 4.1 0.0 0.0046 29 12 55 .. 318 361 .. 312 393 .. 0.68 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0014 Seadorna_VP6 6 eLrdevvdlreenealkaennvLkrklaaLeeer.lktsdlvevvekmdaqvdkigkal 63 + dev++l++ +alkaenn++ +kl ++e e+ lk+ ++ + + +q + + ++l FUN_001941-T1 164 DYYDEVIELKKVINALKAENNIISTKLRRVEGENiLKDRKMEDLLN-QRKQPEDVRRTL 221 5569**************************9877246666666666.445555555555 PP == domain 2 score: 4.1 bits; conditional E-value: 0.0046 Seadorna_VP6 12 vdlreenealkaennvLkrklaaLeeerlktsdlvevvekmdaq 55 l +en++lkaen Lk+ l e + s++ +++ +d FUN_001941-T1 318 KRLADENDHLKAENRGLKKDLLSAIETSAGGSKVPLKADYADMS 361 5799***************9987777767666665555555544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2419 (0.0946956); expected 510.9 (0.02) Passed bias filter: 539 (0.0211); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 19 (0.000743785); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.52u 0.41s 00:00:00.93 Elapsed: 00:00:00.43 # Mc/sec: 10337.58 // Query: FUN_001942-T1 [L=272] Description: FUN_001942 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1063 (0.0416128); expected 510.9 (0.02) Passed bias filter: 538 (0.0210609); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 2774.40 // Query: FUN_001943-T1 [L=759] Description: FUN_001943 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-11 43.3 3.4 1.3e-07 30.9 0.8 2.5 2 PAT1 Topoisomerase II-associated protein PAT1 Domain annotation for each model (and alignments): >> PAT1 Topoisomerase II-associated protein PAT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.7 0.1 1.6e-06 0.042 399 456 .. 373 419 .. 161 424 .. 0.82 2 ! 30.9 0.8 4.9e-12 1.3e-07 513 670 .. 460 606 .. 449 740 .. 0.79 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.6e-06 PAT1 399 nGlmTpqDKnFitRiqlqqLvsAtGnpaeqgsdeslseDFYYqVysqirggqrqnpeq 456 +GlmT+++K+++ +iql qL s ++ +D+Y+q y++ + ++++ eq FUN_001943-T1 373 AGLMTRREKEWLIKIQLLQLTS----------NQPDLDDYYFQTYTRRKT-SKEHVEQ 419 7*******************99..........4556799****9998665.5555555 PP == domain 2 score: 30.9 bits; conditional E-value: 4.9e-12 PAT1 513 eGsLGKisfsnaktPkpLLnikrteseedakrpssakkkaasselsasldrksvLrniEkvYetLmkledheRkmppplaeesdaeleekhkeWke 608 +GsLGK+s ++ P++++++ ++++ ++ k+ ++ l+ + r +vL +iEk Y+ L+++e ++k+ d e +k e FUN_001943-T1 460 QGSLGKVSSASVQHPRQMVDLTIMRNAKAP---EQDKQ-GVTTPLKDTKKRSQVLITIEKGYDFLLSIESIDKKLIH-----VDGEERNKIV---E 543 7*****************876665555533...33333.3333344456899*********************9988.....4445555554...5 PP PAT1 609 klqelneklWeeLkvh.epigattvhPFiallSypKGkkaipRifrhlskeqrvtiLtmivvh 670 + q +kl++ +k+ e+ ++ F+++l + KG+ + R + +k q ++L i + FUN_001943-T1 544 TRQIALTKLFNLFKLStEECDKFDDELFVQFLFIQKGRNLFSRALSMFNKVQIEAVLMAISRN 606 667888999999999626669999**********************99999999999877554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (759 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 742 (0.0290468); expected 510.9 (0.02) Passed bias filter: 545 (0.0213349); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 7231.88 // Query: FUN_001944-T1 [L=315] Description: FUN_001944 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-26 93.5 22.8 2.8e-25 89.8 22.8 2.0 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.7e-06 28.1 18.4 3.2e-06 27.2 17.4 2.0 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.0033 17.5 8.0 0.0033 17.5 8.0 2.8 3 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx ------ inclusion threshold ------ 0.08 12.5 20.0 0.1 12.2 3.7 3.3 3 TAS2R Taste receptor protein (TAS2R) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 89.8 22.8 4.3e-29 2.8e-25 2 260 .] 51 294 .. 50 294 .. 0.84 Alignments for each domain: == domain 1 score: 89.8 bits; conditional E-value: 4.3e-29 xxxxxxxxxx..xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilr..nkklrt.ptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkyk 94 N+lV+l++++ kklr+ p+n+ l+++a+aDllv+l+++p++++ +v++ + ++ a+ v+++ +s+ +++++++DR+la++ pl+yk FUN_001944-T1 51 NTLVLLAVWKdpLKKLRSsPSNFILVSMAFADLLVGLVICPVTAYWGWEIFAKVVSPLDLSVIFAMNVFSVNVSFGHMFLLTVDRFLAVMIPLQYK 146 9*********55589999999***********************8777546677777777888999999999************************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 95 rirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeksk 190 +++t++r+l +++W++ l++++ +l++++ + + ++ +l+++++++++ +++++ +y+ ++++ +++++ FUN_001944-T1 147 SKVTNKRVLRASCICWIYFLVFGCSFLVLREYFAI------------MGA----VYNVQLLVILLGMLVMNFVIVVRFYAYSKEKAHQYQENSRF- 225 ****************************8765333............222....22345555555556668888888888887777777776666. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 191 kkksarkerkalktllvvvvvfvlcwlPyfilllldsllkece.seklvetallitlllayvnsclNPiiY 260 ++e+k+ k ++v+v++f+lc+lP fi+++l +l+k c+ + + + ++ l+y+ns lNPi+Y FUN_001944-T1 226 --IVLQREKKLFKGITVIVCAFLLCYLPWFIVQMLIYLCKPCHpNLSWLMISFGFSGSLTYANSGLNPILY 294 ..788999******************************66665144566777788999************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 17.4 5e-10 3.2e-06 63 254 .. 112 306 .. 44 309 .. 0.71 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 5e-10 7TM_GPCR_Srsx 63 lliivyvfgltaqsvllLvigiDlliavkfPirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliin. 157 ++ ++ vf++ ++ + ++++D+++av++P++Y++ ++k +l +++ +y +++ ++fl+ + +i+ a+ + ++ l +l++n FUN_001944-T1 112 VIFAMNVFSVNVSFGHMFLLTVDRFLAVMIPLQYKSKVTNKRVLRASCICWIYF-LVFGCSFLVLREYFAIM----GAVYNVQLLVILLGMLVMNf 202 5667889999999999999****************9988886666666666663.55677788877775554....44444445666666666662 PP 7TM_GPCR_Srsx 158 vivllvylvliiilkkkkek....kkssskkvlkslkvtvvififg...WftstilntvllalteseevekliqayagilvllsfsqnffVtywrs 246 viv+ y+++ ++++++e+ ++ kk++k ++v v+ f+++ Wf++++l ++ + ++ + + g l+ ++ n + + wr FUN_001944-T1 203 VIVVRFYAYSKEKAHQYQENsrfiVLQREKKLFKGITVIVCAFLLCylpWFIVQMLIYLCKPCHPNLSWLMISFGFSGSLTYANSGLNPILYTWRI 298 34455667777777777776555555889***************987779******999999999*****9999999999999999********** PP 7TM_GPCR_Srsx 247 seYrkafr 254 ++Y+++++ FUN_001944-T1 299 PKYKETLK 306 ****9876 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 8.0 5.2e-07 0.0033 29 130 .. 72 174 .. 41 182 .. 0.62 2 ! 5.8 1.1 0.002 13 164 200 .. 188 224 .. 177 247 .. 0.75 3 ? -0.8 1.7 0.2 1.3e+03 101 136 .. 229 266 .. 225 281 .. 0.70 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 5.2e-07 7TM_GPCR_Srx 29 gilclskaisnaiilliflfyvvPmt.llqsellkellnsh.liglialglYeispls..qllialNRfcavffplkyekifsiknTkiiiviiwi 120 + + +s a++++++ l+++ P+t + + e++ ++++ l ++a+ +++++ + +l++++Rf+av++pl+y++ ++k + +i+wi FUN_001944-T1 72 NFILVSMAFADLLVGLVIC----PVTaYWGWEIFAKVVSPLdLSVIFAMNVFSVNVSFghMFLLTVDRFLAVMIPLQYKSKVTNKRVLRASCICWI 163 5566666666655544432....2221233333333322212445555555555544321589********************************* PP 7TM_GPCR_Srx 121 vslif.itvly 130 + l+f + +l FUN_001944-T1 164 YFLVFgCSFLV 174 ****9877554 PP == domain 2 score: 5.8 bits; conditional E-value: 0.002 7TM_GPCR_Srx 164 llililviitlvlnlltaiklilskkkskstsseesk 200 + l++++ +lv+n++++++ + ++k+++++ +e+s+ FUN_001944-T1 188 VQLLVILLGMLVMNFVIVVRFYAYSKEKAHQYQENSR 224 4567888899************888888877776654 PP == domain 3 score: -0.8 bits; conditional E-value: 0.2 7TM_GPCR_Srx 101 kyekifsiknTkiiiviiwivslifit..vlylpegCk 136 + ek + +T+i+ +++ + +fi+ ++yl + C+ FUN_001944-T1 229 QREKKLFKGITVIVCAFLLCYLPWFIVqmLIYLCKPCH 266 55566666778888777777777765555888888887 PP >> TAS2R Taste receptor protein (TAS2R) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 3.7 1.6e-05 0.1 11 63 .. 38 90 .. 30 153 .. 0.81 2 ? 4.7 5.6 0.003 19 130 203 .. 190 258 .. 172 260 .. 0.69 3 ? 5.2 1.6 0.0021 13 235 269 .. 241 275 .. 230 311 .. 0.86 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 1.6e-05 TAS2R 11 ivavvefllgilgngfivlvncidwvkkrklssidliLlsLaisRilllwlil 63 i++++ + +++l+n+++ l ++d +kk + s++++iL+s+a + +l+ ++i FUN_001944-T1 38 ILSIIMSPIIVLANTLVLLAVWKDPLKKLRSSPSNFILVSMAFADLLVGLVIC 90 678888999*********************************99887655554 PP == domain 2 score: 4.7 bits; conditional E-value: 0.003 TAS2R 130 vlwlLLgsllisllllvkiikeikasidlellklkrnttlklkeeklellsslvllnlgvllpfivflisflLL 203 +l++LLg+l+++++++v +++ +k+++ +++++n+ + + +++ +l+ +++ + +l + + + + +L FUN_001944-T1 190 LLVILLGMLVMNFVIVVRFYAYSKEKA----HQYQENSRFIVLQREKKLFKGITVI-VCAFLLCYLPWFIVQML 258 6789*********88888888777654....4888888887666666655555544.45555555555555555 PP == domain 3 score: 5.2 bits; conditional E-value: 0.0021 TAS2R 235 slisFllLyilyflsilisiislllpknkllliig 269 ++ Fll y+ +f++ ++ ++++ ++ n +l+i+ FUN_001944-T1 241 IVCAFLLCYLPWFIVQMLIYLCKPCHPNLSWLMIS 275 45679*********99999************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (315 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1373 (0.0537483); expected 510.9 (0.02) Passed bias filter: 532 (0.020826); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.42s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3165.43 // Query: FUN_001945-T1 [L=339] Description: FUN_001945 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-26 92.0 21.7 3.4e-17 63.3 6.6 2.2 2 7tm_1 7 transmembrane receptor (rhodopsin family) 3.1e-07 30.9 15.5 1.7e-06 28.5 8.2 2.3 2 7tm_4 Olfactory receptor 2.9e-06 27.4 19.3 2.7e-05 24.2 19.3 2.0 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.0037 17.8 1.4 0.0037 17.8 1.4 2.9 3 Serpentine_r_xa Caenorhabditis serpentine receptor-like prot ------ inclusion threshold ------ 0.29 11.1 23.1 0.21 11.6 10.8 2.3 2 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.3 6.6 6.7e-21 3.4e-17 1 123 [. 51 175 .. 51 181 .. 0.88 2 ! 34.8 7.1 3.2e-12 1.6e-08 155 260 .] 184 297 .. 176 297 .. 0.82 Alignments for each domain: == domain 1 score: 63.3 bits; conditional E-value: 6.7e-21 xxxxxxxxxxx..xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrt.ptnifllnLavaDllvlllvlpfal.vyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+lVi+++++ k lr+ ptn+ ll +a aDl v+++ p + ++++ e++ + +++ +vt++ +++++s +++++++iDRY a+ kplk FUN_001945-T1 51 GNTLVIVAVVKdpLKTLRSsPTNFILLEMASADLFVGMVLAPSFAlLNFSFEEKAAWDSLF--FVTFFSHFFVIVSAYHVFLLTIDRYFALAKPLK 144 8**********554789999*****************877775551666676777777776..99******************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllf 123 yk+i+tk+r+++ +Wv++l + + l++ FUN_001945-T1 145 YKAIVTKTRVVLGSSSIWVFSLSYAALTLTI 175 ***********************99998875 PP == domain 2 score: 34.8 bits; conditional E-value: 3.2e-12 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx. RF 7tm_1 155 lllsvlgfllpllvilvcyvrilrtlrksakkeks.......kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetal. 242 +l++vl ++l i+ yv++l l k+ k++ + ++ + ++e+k+ +++ v+++f +c++P +++l+ +++++c+++ + FUN_001945-T1 184 WLIFVLLLFLSSEGISLAYVLTLANLVKHYKAKMKdtenshfNQLRLYQREKKVSLVIFSVIIAFDICYFPWIVVQLVFVFCQSCSASYRAVIVSr 279 56788888889999*********99999988877756666654444556667*****************************888876655444444 PP xxxxxxxxxxxxxxxxxx RF 7tm_1 243 litlllayvnsclNPiiY 260 ++++ll+++ns lNP++Y FUN_001945-T1 280 DVAMLLIFINSSLNPLLY 297 99***************9 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.5 8.2 3.3e-10 1.7e-06 1 124 [. 41 167 .. 41 218 .. 0.79 2 ! 6.8 0.7 0.0014 7.1 210 268 .. 240 303 .. 226 314 .. 0.76 Alignments for each domain: == domain 1 score: 28.5 bits; conditional E-value: 3.3e-10 7tm_4 1 fclvyliillGnl.tilfvikte.aslh.qPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesavllamavdrf 93 f++v +i+++Gn+ +i+ v+k ++l P + l +a +dl + + P + + + ++++ ++ +ff h f+++ + + ++dr+ FUN_001945-T1 41 FSIVSIITVIGNTlVIVAVVKDPlKTLRsSPTNFILLEMASADLFVGMVLAPSFALLNFSFEEKAAWDSLFFVTFFSHFFVIVSAYHVFLLTIDRY 136 7899********736778888752455426888888889*********9999976665555566899***************************** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvi 124 a+ +pl+y +i t++++ + ++v s+ FUN_001945-T1 137 FALAKPLKYKAIVTKTRVVLGSSSIWVFSLS 167 ****************998777777766554 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0014 7tm_4 210 tcgshvcavlafyvPmiglsvvhrfgkkvsrllqvll.....anlyllfPPvlnPivysvktke 268 s ++a + y P i + +v f + s ++++ a l +++ lnP++ys + + FUN_001945-T1 240 VIFSVIIAFDICYFPWIVVQLVFVFCQSCSASYRAVIvsrdvAMLLIFINSSLNPLLYSWRFSK 303 345778888899***************99986666542333378889999*********88655 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 19.3 5.4e-09 2.7e-05 2 257 .] 46 312 .. 45 312 .. 0.73 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 5.4e-09 7TM_GPCR_Srsx 2 vvGliGNvllilltfkk..kkLrs.kssiLicvqcladllclvgelv.fvvllltg.tqlkreeCFlliivyvfgltaqsvllLvigiDlliavkf 92 ++ +iGN l+i++++k k Lrs +++ ++ + adl++ + + f++l++++ ++ + F++ ++ f++++++ + +++iD+ +a + FUN_001945-T1 46 IITVIGNTLVIVAVVKDplKTLRSsPTNFILLEMASADLFVGMVLAPsFALLNFSFeEKAAWDSLFFVTFFSHFFVIVSAYHVFLLTIDRYFALAK 141 899*************85589*9736777777788999987655544144466655156677899******************************* PP 7TM_GPCR_Srsx 93 PirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek........... 177 P++Y+ + +++ +++ ++s++ +l l++ + +++ ++l + + + ++ +++l lv+ ++k k+++ FUN_001945-T1 142 PLKYKAIVTKTRVVLGSSSIWVFSLSYAALT-LTIGARALMIPWLIFVL----LLFLSSEGISLAYVLTLANLVKHYKAKMKDTEnshfnqlrlyq 232 *******999844444444444444433332.22333333444444444....2223333344444444555555555555555477788898887 PP 7TM_GPCR_Srsx 178 kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrell 257 ++++++ v+ s+ + i f W+++++++ ++ + s + + a++l+++++s n + wr s+++ +++ + FUN_001945-T1 233 REKKVSLVIFSVIIAFDICYFPWIVVQLVFVFCQSCSASYRAVIVSRDVAMLLIFINSSLNPLLYSWRFSKFQATYKYFW 312 778888888899999999999*************9999999988888889999********************9998776 PP >> Serpentine_r_xa Caenorhabditis serpentine receptor-like protein, class xa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 0.4 2e+03 88 103 .. 36 49 .. 17 95 .. 0.67 2 ! 17.8 1.4 7.2e-07 0.0037 47 100 .. 113 166 .. 108 177 .. 0.90 3 ? -1.2 4.2 0.5 2.6e+03 77 131 .. 220 273 .. 181 293 .. 0.67 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.4 Serpentine_r_xa 88 vvlysvivlilvlilL 103 ++++++++ +++i + FUN_001945-T1 36 ILCVCFSI--VSIITV 49 33333322..222221 PP == domain 2 score: 17.8 bits; conditional E-value: 7.2e-07 Serpentine_r_xa 47 itlvgtlfYliplflsvlmtlqRisivikPlkqkiwftdkkvvlysvivlilvl 100 +t+ +f ++ + +l+t++R +++ kPlk k +t+++vvl s+++ +++l FUN_001945-T1 113 VTFFSHFFVIVSAYHVFLLTIDRYFALAKPLKYKAIVTKTRVVLGSSSIWVFSL 166 5677778888889999**********************************9986 PP == domain 3 score: -1.2 bits; conditional E-value: 0.5 Serpentine_r_xa 77 lkqkiwftdkkvvlysvivlilvlilLlipylseCsvnfnartlsfesaCaperh 131 + ++ +f++ +++ v+++++ +++ + + + + +++++f C + FUN_001945-T1 220 T-ENSHFNQLRLYQREKKVSLVIFSVIIAFDICYFPWIVVQLVFVFCQSCSASYR 273 3.34678888888888888887777777766777777788888888888876654 PP >> 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 10.8 4e-05 0.21 6 135 .. 35 168 .. 31 176 .. 0.71 2 ? 6.0 3.5 0.002 10 35 87 .. 233 288 .. 220 295 .. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4e-05 7TM_GPCR_Srbc 6 vvvtligilfsiitivlniylllkiflk..kkikkkkdlvLfyfrfalDvvyslsvsiyllyvlllsiskeelvknlifylglpssnigaiRsila 99 ++ +++ ++siit++ n+ ++++++ + k+++ + ++ +D+++++++ ++ ll ++e++ +f+++++s + ++ + + FUN_001945-T1 35 TILCVCFSIVSIITVIGNTLVIVAVVKDplKTLRSSPTNFILLEMASADLFVGMVL--APSFALLNFSFEEKAAWDSLFFVTFFSHFFVIVSAYHV 128 66677777889999999999999998542245555555444444556788877665..45666666777778877888999999************ PP 7TM_GPCR_Srbc 100 llIsleRviAvyfPifyhnyrskipnl....lililiill 135 +l++++R +A+ P+ y+ k ++ i+++ +++ FUN_001945-T1 129 FLLTIDRYFALAKPLKYKAIVTKTRVVlgssSIWVFSLSY 168 *****************97766654430000455555555 PP == domain 2 score: 6.0 bits; conditional E-value: 0.002 7TM_GPCR_Srbc 35 kikkkkdlvLfyfrfalDvvyslsvsiyllyvlllsiskeel....vknlifylglp 87 + +kk +lv+f + +a+D++y +++ l++v++ s+s ++ + + ++l+++ FUN_001945-T1 233 R-EKKVSLVIFSVIIAFDICYFPWIVVQLVFVFCQSCSASYRavivSRDVAMLLIFI 288 4.6999***************************999988765444445555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (339 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1776 (0.0695244); expected 510.9 (0.02) Passed bias filter: 673 (0.0263457); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3321.55 // Query: FUN_001946-T1 [L=324] Description: FUN_001946 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-26 92.3 21.2 3.1e-17 63.4 6.6 2.2 2 7tm_1 7 transmembrane receptor (rhodopsin family) 1.3e-07 32.2 15.0 1.4e-06 28.8 8.1 2.3 2 7tm_4 Olfactory receptor 3.2e-06 27.2 18.7 3.4e-05 23.9 18.7 2.0 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 0.003 18.0 1.3 0.003 18.0 1.3 2.9 3 Serpentine_r_xa Caenorhabditis serpentine receptor-like prot ------ inclusion threshold ------ 0.034 14.1 19.3 0.19 11.7 10.8 2.3 2 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.4 6.6 6.1e-21 3.1e-17 1 123 [. 51 175 .. 51 181 .. 0.88 2 ! 35.0 6.5 2.7e-12 1.4e-08 155 260 .] 184 297 .. 176 297 .. 0.82 Alignments for each domain: == domain 1 score: 63.4 bits; conditional E-value: 6.1e-21 xxxxxxxxxxx..xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilr..nkklrt.ptnifllnLavaDllvlllvlpfal.vyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplk 92 gN+lVi+++++ k lr+ ptn+ ll +a aDl v+++ p + ++++ e++ + +++ +vt++ +++++s +++++++iDRY a+ kplk FUN_001946-T1 51 GNTLVIVAVVKdpLKTLRSsPTNFILLEMASADLFVGMVLAPSFAlLNFSFEEKAAWDSLF--FVTFFSHFFVIVSAYHVFLLTIDRYFALAKPLK 144 8**********554789999*****************877775551666676777777776..99******************************* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 93 ykrirtkrralvlilvvWvlalllslppllf 123 yk+i+tk+r+++ +Wv++l + + l++ FUN_001946-T1 145 YKAIVTKTRVVLGSSSIWVFSLSYAALTLTI 175 ***********************99998875 PP == domain 2 score: 35.0 bits; conditional E-value: 2.7e-12 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx. RF 7tm_1 155 lllsvlgfllpllvilvcyvrilrtlrksakkeks.......kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetal. 242 +l++vl ++l i+ yv++l l k+ k++ + ++ + ++e+k+ +++ v+++f +c++P +++l+ +++++c+++ + FUN_001946-T1 184 WLIFVLLLFLSSEGISLAYVLTLANLVKHYKARMKdtenshfNQLRLYQREKKVSLVIFSVIIAFDVCYFPWIVVQLVFAFCQSCSASYRAVIVSr 279 56788888889999*********99999988877756666654445556667*****************************888876655444444 PP xxxxxxxxxxxxxxxxxx RF 7tm_1 243 litlllayvnsclNPiiY 260 ++++ll+++ns lNP++Y FUN_001946-T1 280 DVAMLLIFINSSLNPLLY 297 99***************9 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 8.1 2.7e-10 1.4e-06 1 124 [. 41 167 .. 41 215 .. 0.80 2 ! 7.5 0.6 0.00087 4.4 210 268 .. 240 303 .. 226 313 .. 0.76 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 2.7e-10 7tm_4 1 fclvyliillGnl.tilfvikte.aslh.qPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesavllamavdrf 93 f++v +i+++Gn+ +i+ v+k ++l P + l +a +dl + + P + + + ++++ ++ +ff h f+++ + + ++dr+ FUN_001946-T1 41 FSIVSIITVIGNTlVIVAVVKDPlKTLRsSPTNFILLEMASADLFVGMVLAPSFALLNFSFEEKAAWDSLFFVTFFSHFFVIVSAYHVFLLTIDRY 136 7899********736778888752455426888888889*********9999976665555566899***************************** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvi 124 a+ +pl+y +i t++++ + ++v s+ FUN_001946-T1 137 FALAKPLKYKAIVTKTRVVLGSSSIWVFSLS 167 ****************998777777766554 PP == domain 2 score: 7.5 bits; conditional E-value: 0.00087 7tm_4 210 tcgshvcavlafyvPmiglsvvhrfgkkvsrllqvll.....anlyllfPPvlnPivysvktke 268 s ++a + y P i + +v f + s ++++ a l +++ lnP++ys + + FUN_001946-T1 240 VIFSVIIAFDVCYFPWIVVQLVFAFCQSCSASYRAVIvsrdvAMLLIFINSSLNPLLYSWRFSK 303 345778888899***************99986666542333378889999*********88655 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 18.7 6.6e-09 3.4e-05 2 257 .] 46 312 .. 45 312 .. 0.71 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 6.6e-09 7TM_GPCR_Srsx 2 vvGliGNvllilltfkk..kkLrs.kssiLicvqcladllclvgelv.fvvllltg.tqlkreeCFlliivyvfgltaqsvllLvigiDlliavkf 92 ++ +iGN l+i++++k k Lrs +++ ++ + adl++ + + f++l++++ ++ + F++ ++ f++++++ + +++iD+ +a + FUN_001946-T1 46 IITVIGNTLVIVAVVKDplKTLRSsPTNFILLEMASADLFVGMVLAPsFALLNFSFeEKAAWDSLFFVTFFSHFFVIVSAYHVFLLTIDRYFALAK 141 899*************85589*9736777777788999987655544144466655156677899******************************* PP 7TM_GPCR_Srsx 93 PirYrllskekYllillifpvlyssiilvlgflqrddetiivCapplalagkaseiftlssliinvivllvylvliiilkkkkek........... 177 P++Y+ + +++ +++ ++s++ +l ++ + +++ ++l + + + ++ +++l lv+ +++ k+++ FUN_001946-T1 142 PLKYKAIVTKTRVVLGSSSIWVFSLSYAALTL-TIGARALMIPWLIFVL----LLFLSSEGISLAYVLTLANLVKHYKARMKDTEnshfnqlrlyq 232 *******9998444443333334433333322.2223333333333333....2222333333444444444444444444444456688888877 PP 7TM_GPCR_Srsx 178 kkssskkvlkslkvtvvififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrell 257 ++++++ v+ s+ + + f W++++++++++ + s + + a++l+++++s n + wr s+++ +++ + FUN_001946-T1 233 REKKVSLVIFSVIIAFDVCYFPWIVVQLVFAFCQSCSASYRAVIVSRDVAMLLIFINSSLNPLLYSWRFSKFQATYKYFW 312 777777788888888888899*************9999999998888889999********************9998776 PP >> Serpentine_r_xa Caenorhabditis serpentine receptor-like protein, class xa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.1 0.37 1.9e+03 89 103 .. 37 49 .. 17 95 .. 0.67 2 ! 18.0 1.3 6e-07 0.003 47 100 .. 113 166 .. 108 181 .. 0.90 3 ? -1.4 3.8 0.57 2.9e+03 78 130 .. 221 272 .. 181 293 .. 0.65 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.37 Serpentine_r_xa 89 vlysvivlilvlilL 103 +++++++ +++i + FUN_001946-T1 37 LCVCFSI--VSIITV 49 3333322..222221 PP == domain 2 score: 18.0 bits; conditional E-value: 6e-07 Serpentine_r_xa 47 itlvgtlfYliplflsvlmtlqRisivikPlkqkiwftdkkvvlysvivlilvl 100 +t+ +f ++ + +l+t++R +++ kPlk k +t+++vvl s+++ +++l FUN_001946-T1 113 VTFFSHFFVIVSAYHVFLLTIDRYFALAKPLKYKAIVTKTRVVLGSSSIWVFSL 166 5677778888889999**********************************9986 PP == domain 3 score: -1.4 bits; conditional E-value: 0.57 Serpentine_r_xa 78 kqkiwftdkkvvlysvivlilvlilLlipylseCsvnfnartlsfesaCaper 130 + + +f++ +++ v+++++ +++ + + + ++++ f C + FUN_001946-T1 221 E-NSHFNQLRLYQREKKVSLVIFSVIIAFDVCYFPWIVVQLVFAFCQSCSASY 272 3.356888777777777777777666665566666667777777777776654 PP >> 7TM_GPCR_Srbc Serpentine type 7TM GPCR chemoreceptor Srbc # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 10.8 3.7e-05 0.19 6 135 .. 35 168 .. 31 176 .. 0.71 2 ? 7.4 1.3 0.00074 3.8 35 87 .. 233 288 .. 220 296 .. 0.77 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3.7e-05 7TM_GPCR_Srbc 6 vvvtligilfsiitivlniylllkiflk..kkikkkkdlvLfyfrfalDvvyslsvsiyllyvlllsiskeelvknlifylglpssnigaiRsila 99 ++ +++ ++siit++ n+ ++++++ + k+++ + ++ +D+++++++ ++ ll ++e++ +f+++++s + ++ + + FUN_001946-T1 35 TILCVCFSIVSIITVIGNTLVIVAVVKDplKTLRSSPTNFILLEMASADLFVGMVL--APSFALLNFSFEEKAAWDSLFFVTFFSHFFVIVSAYHV 128 66677777889999999999999998542245555555444444556788877665..45666666777778877888999999************ PP 7TM_GPCR_Srbc 100 llIsleRviAvyfPifyhnyrskipnl....lililiill 135 +l++++R +A+ P+ y+ k ++ i+++ +++ FUN_001946-T1 129 FLLTIDRYFALAKPLKYKAIVTKTRVVlgssSIWVFSLSY 168 *****************97766654430000455555555 PP == domain 2 score: 7.4 bits; conditional E-value: 0.00074 7TM_GPCR_Srbc 35 kikkkkdlvLfyfrfalDvvyslsvsiyllyvlllsiskeel....vknlifylglp 87 + +kk +lv+f + +a+Dv+y +++ l++ ++ s+s ++ + + ++l+++ FUN_001946-T1 233 R-EKKVSLVIFSVIIAFDVCYFPWIVVQLVFAFCQSCSASYRavivSRDVAMLLIFI 288 4.6899**********************99999999987765444445555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (324 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1510 (0.0591114); expected 510.9 (0.02) Passed bias filter: 558 (0.0218438); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3204.62 // Query: FUN_001947-T1 [L=1186] Description: FUN_001947 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-36 125.0 0.1 1.1e-35 124.0 0.1 1.5 1 UCH Ubiquitin carboxyl-terminal hydrolase 5.2e-30 104.4 7.3 1.1e-29 103.5 7.3 1.5 1 USP8_dimer USP8 dimerisation domain 2.9e-07 30.9 0.5 5.8e-07 29.9 0.5 1.6 1 WW WW domain 3.9e-07 30.5 0.1 7.9e-07 29.5 0.1 1.5 1 UCH_1 Ubiquitin carboxyl-terminal hydrolase 0.0082 17.0 0.0 0.023 15.6 0.0 1.8 1 Rhodanese Rhodanese-like domain Domain annotation for each model (and alignments): >> UCH Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 124.0 0.1 2.1e-39 1.1e-35 1 145 [. 980 1149 .. 980 1170 .. 0.93 Alignments for each domain: == domain 1 score: 124.0 bits; conditional E-value: 2.1e-39 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 1 vGlkNlgntCymnsvlQaLlsipelrdlllrieeekedseeekei...nllkalaklfkelqkkkksssvkPkklkkllgklneefsgykqqDa 91 +Gl+NlgntCymnsv+Q+L+s+++l+ ++ + + ++ ++++ + +l++ ++ l++ l+ + + ++v+P+++k+++gk++++fsgy+qqD+ FUN_001947-T1 980 TGLRNLGNTCYMNSVVQCLSSVTPLSAFFISGAFREDINRTNRDGtrgELAEIFSVLVRVLH-SGQFKCVSPNEFKRTIGKFKSQFSGYDQQDS 1072 7******************************9999999999988855558888888888777.669**************************** PP xxxxxxxxxxxxxxxxx.......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 92 qEfleflLdqlheklnk.......................wekaskeeeslitdlFrgqlksrlkckeceeeklkik 145 qE+l+fl+d+lhe+lnk we+++ ++ s++++lF g + s++kc c++e+ k++ FUN_001947-T1 1073 QELLAFLMDGLHEDLNKvkqkpylkapsddldpetaakiaWENHKMRNASIMVELFDGLFMSTVKCIVCGKESRKFD 1149 ***************************************99******************************977766 PP >> USP8_dimer USP8 dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 103.5 7.3 2.1e-33 1.1e-29 2 113 .. 7 117 .. 6 118 .. 0.98 Alignments for each domain: == domain 1 score: 103.5 bits; conditional E-value: 2.1e-33 USP8_dimer 2 klkplhlsssleeLeelaeklevdknkslkrllrsanklvktAeeyrlegdeEkAYilymkylnllekIrkhpdyksdkakvrqmlgkkklnkvil 97 +lk lhl+ +le+L++la+ ++ ++n+++++l++sa+k++ +A+ ++legdeE+AY++ym+y+nl+++I+k+++yk+ ++ +++ lgk+k+ + i FUN_001947-T1 7 TLKALHLATNLEHLNKLADLKSGNRNANPQILVKSADKVYLQAQSHYLEGDEESAYVFYMRYFNLITLIKKSSKYKETQKFYDDLLGKSKIINSI- 101 6899******************************************************************************************6. PP USP8_dimer 98 delEklkesLeerYee 113 + +E l++sL++rYe+ FUN_001947-T1 102 EHAEALQSSLSKRYEK 117 **************96 PP >> WW WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.5 1.1e-10 5.8e-07 1 31 [] 847 875 .. 847 875 .. 0.97 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 1.1e-10 WW 1 LPpgWeeawdpdsGrvYYyNhnTgetqWekP 31 LPpgWe+++d + + Y+ +hnT++t+We P FUN_001947-T1 847 LPPGWEKVVDGE--KLYFKDHNTQTTHWEMP 875 8***********..6**************99 PP >> UCH_1 Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.1 1.5e-10 7.9e-07 2 165 .. 981 1160 .. 980 1181 .. 0.84 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 1.5e-10 UCH_1 2 GLEthiansYtNslLQllrfipplrnlalshlateckke.......ncLlcElgflfdmlekakgkncqasNFlkalssipeasalglleeeee 88 GL + +++Y+Ns++Q+l ++pl + +s + +e+ + L + l++ l+ + k ++ + F +++++++ s++ ++++ FUN_001947-T1 981 GLRNLGNTCYMNSVVQCLSSVTPLSAFFISGAFREDINRtnrdgtrGELAEIFSVLVRVLHSGQFKCVSPNEFKRTIGKFK--SQFSGYDQQD- 1071 99****************************999977766677666556666667777999*9**99***************..5555534422. PP UCH_1 89 skkkaslssliqsfnrflleqlsseekstkkns.......................seaeseleqllgikaettirclsCgsesekesstlvld 159 q++ fl++ l+++ +++k+++ +++s + +l+ +t++c+ Cg+es+k + l FUN_001947-T1 1072 ----------SQELLAFLMDGLHEDLNKVKQKPylkapsddldpetaakiawenhkMRNASIMVELFDGLFMSTVKCIVCGKESRKFDAFSNLT 1155 ..........38899***************999**********************9888899999*********************99999988 PP UCH_1 160 liypkk 165 l p + FUN_001947-T1 1156 LPLP-S 1160 8444.2 PP >> Rhodanese Rhodanese-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 4.4e-06 0.023 1 99 [. 218 341 .. 218 343 .. 0.63 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 4.4e-06 Rhodanese 1 saeelkelledgkvv...liDvRppeeyakghI..pgAvnv.......sltrlslppapllellekllel.dkdktivvycesgnraaaa..aall 81 sa++l+++l+ +++ +iD+Rp + +++ I p+ +n+ +++s ++ l+e +++ ++ +++ +v+ +es + + +++ FUN_001947-T1 218 SAQDLYDMLKGENMCkvlVIDCRPHSVFEENNInfPSCINIpselldsGVSAGSI-ERRLNEDTRQIWNRrGEKEFVVLMDESTKVNDITpeCRIQ 312 578899999777655788************99999******88766533333333.3333333333333335555555555555557777754444 PP Rhodanese 82 k......k....lGykn.vyvldGGfeaW 99 + k +k+ +ldGGf +W FUN_001947-T1 313 RlkdvifKfdsnSSLKRePLILDGGFHSW 341 454555514455334555*********99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1186 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1482 (0.0580153); expected 510.9 (0.02) Passed bias filter: 672 (0.0263065); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.47u 0.42s 00:00:00.88 Elapsed: 00:00:00.43 # Mc/sec: 11218.67 // Query: FUN_001947-T2 [L=1322] Description: FUN_001947 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.4e-74 249.5 0.3 9.6e-74 248.7 0.3 1.4 1 UCH Ubiquitin carboxyl-terminal hydrolase 6.1e-30 104.2 7.3 1.2e-29 103.3 7.3 1.5 1 USP8_dimer USP8 dimerisation domain 1.2e-18 68.4 0.2 2e-18 67.6 0.2 1.4 1 UCH_1 Ubiquitin carboxyl-terminal hydrolase 3.2e-07 30.8 0.5 6.6e-07 29.8 0.5 1.6 1 WW WW domain 0.0098 16.8 0.0 0.026 15.4 0.0 1.7 1 Rhodanese Rhodanese-like domain Domain annotation for each model (and alignments): >> UCH Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 248.7 0.3 1.9e-77 9.6e-74 1 254 [] 980 1308 .. 980 1308 .. 0.96 Alignments for each domain: == domain 1 score: 248.7 bits; conditional E-value: 1.9e-77 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 1 vGlkNlgntCymnsvlQaLlsipelrdlllrieeekedseeekei...nllkalaklfkelqkkkksssvkPkklkkllgklneefsgykqqDa 91 +Gl+NlgntCymnsv+Q+L+s+++l+ ++ + + ++ ++++ + +l++ ++ l++ l+ + + ++v+P+++k+++gk++++fsgy+qqD+ FUN_001947-T2 980 TGLRNLGNTCYMNSVVQCLSSVTPLSAFFISGAFREDINRTNRDGtrgELAEIFSVLVRVLH-SGQFKCVSPNEFKRTIGKFKSQFSGYDQQDS 1072 7******************************9999999999988855558888888888777.669**************************** PP xxxxxxxxxxxxxxxxx.......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...................... RF UCH 92 qEfleflLdqlheklnk.......................wekaskeeeslitdlFrgqlksrlkckeceee...................... 140 qE+l+fl+d+lhe+lnk we+++ ++ s++++lF g + s++kc c++e FUN_001947-T2 1073 QELLAFLMDGLHEDLNKvkqkpylkapsddldpetaakiaWENHKMRNASIMVELFDGLFMSTVKCIVCGKEsrkfdafsnltlplpshtnrct 1166 ***************************************99***************************************************** PP .................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx RF UCH 141 .................................klkikrlPevLiihlkRfsynrevkeKlntevefpe.eldlseylaeeekektkekkkYeL 200 +++i++lP vL++hlkRf+y++++++Kl+t+v+fp+ ++d+s+++ + +k + Y+L FUN_001947-T2 1167 lwdclhlftkpekmtgddkwfcpncrqrreatkTIQIWKLPAVLVVHLKRFQYEGMWRQKLQTNVSFPMsQVDMSNHIVGPRSQK-P----YQL 1255 ********************************************************************98*****9998555544.3....*** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 201 vavvvHsGslssGHYiayikaeeknkWvkfdDekvsevdeekevlsesayiLfY 254 +av++H+G++++GHY+a++k+ ++kW+kfdD+ v+e++ + ev ++++y+LfY FUN_001947-T2 1256 FAVSNHYGTMHGGHYTAFAKNVYDKKWYKFDDQYVTEMSPR-EVVTSAGYLLFY 1308 ***************************************98.89999******* PP >> USP8_dimer USP8 dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 103.3 7.3 2.4e-33 1.2e-29 2 113 .. 7 117 .. 6 118 .. 0.98 Alignments for each domain: == domain 1 score: 103.3 bits; conditional E-value: 2.4e-33 USP8_dimer 2 klkplhlsssleeLeelaeklevdknkslkrllrsanklvktAeeyrlegdeEkAYilymkylnllekIrkhpdyksdkakvrqmlgkkklnkvil 97 +lk lhl+ +le+L++la+ ++ ++n+++++l++sa+k++ +A+ ++legdeE+AY++ym+y+nl+++I+k+++yk+ ++ +++ lgk+k+ + i FUN_001947-T2 7 TLKALHLATNLEHLNKLADLKSGNRNANPQILVKSADKVYLQAQSHYLEGDEESAYVFYMRYFNLITLIKKSSKYKETQKFYDDLLGKSKIINSI- 101 6899******************************************************************************************6. PP USP8_dimer 98 delEklkesLeerYee 113 + +E l++sL++rYe+ FUN_001947-T2 102 EHAEALQSSLSKRYEK 117 **************96 PP >> UCH_1 Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.6 0.2 4e-22 2e-18 2 316 .. 981 1289 .. 980 1290 .. 0.83 Alignments for each domain: == domain 1 score: 67.6 bits; conditional E-value: 4e-22 UCH_1 2 GLEthiansYtNslLQllrfipplrnlalshlateckke.......ncLlcElgflfdmlekakgkncqasNFlkalssipeasalglleeeee 88 GL + +++Y+Ns++Q+l ++pl + +s + +e+ + L + l++ l+ + k ++ + F +++++++ s++ ++++ FUN_001947-T2 981 GLRNLGNTCYMNSVVQCLSSVTPLSAFFISGAFREDINRtnrdgtrGELAEIFSVLVRVLHSGQFKCVSPNEFKRTIGKFK--SQFSGYDQQD- 1071 99****************************999977766677666556666667777999*9**99***************..5555534422. PP UCH_1 89 skkkaslssliqsfnrflleqlsseekstkkns.......................seaeseleqllgikaettirclsCgsesekesstlvld 159 q++ fl++ l+++ +++k+++ +++s + +l+ +t++c+ Cg+es+k + l FUN_001947-T2 1072 ----------SQELLAFLMDGLHEDLNKVKQKPylkapsddldpetaakiawenhkMRNASIMVELFDGLFMSTVKCIVCGKESRKFDAFSNLT 1155 ..........38899***************999**********************9888899999*************************9999 PP UCH_1 160 liyp.kkssnekkkknltfssilksslerektt...kawCekCkkyqtlesrrtvknlPpvLslnaaltseeelelWkdknwLpkeigltldkd 249 l p ++ +++ t+ ++l + + ek t k +C++C++ +++ ++ +lP+vL+++++ + e +W++k L++++++ +++ FUN_001947-T2 1156 L--PlPSH-----TNRCTLWDCLHLFTKPEKMTgddKWFCPNCRQRREATKTIQIWKLPAVLVVHLKRFQYE--GMWRQK--LQTNVSFPMSQV 1238 9..52222.....34577777777777776665554999******99999999999***********98666..899985..777777766664 PP UCH_1 250 kldlklklqeekekeeeeivvYeLvgvVveikdskekkshLvslvkvaeseaeaekesqWylFNDfl 316 + ++++ + ++ + Y+L +v + + + + +h+ +++k +++Wy F+D FUN_001947-T2 1239 D--MSNHIVGP-----RSQKPYQLFAVSNHYG-TMH-GGHYTAFAKN-------VYDKKWYKFDDQY 1289 3..44444444.....45678***********.654.9*******94.......3568*******65 PP >> WW WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.5 1.3e-10 6.6e-07 1 31 [] 847 875 .. 847 875 .. 0.97 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 1.3e-10 WW 1 LPpgWeeawdpdsGrvYYyNhnTgetqWekP 31 LPpgWe+++d + + Y+ +hnT++t+We P FUN_001947-T2 847 LPPGWEKVVDGE--KLYFKDHNTQTTHWEMP 875 8***********..6**************99 PP >> Rhodanese Rhodanese-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 5.1e-06 0.026 1 99 [. 218 341 .. 218 343 .. 0.63 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 5.1e-06 Rhodanese 1 saeelkelledgkvv...liDvRppeeyakghI..pgAvnv.......sltrlslppapllellekllel.dkdktivvycesgnraaaa..aall 81 sa++l+++l+ +++ +iD+Rp + +++ I p+ +n+ +++s ++ l+e +++ ++ +++ +v+ +es + + +++ FUN_001947-T2 218 SAQDLYDMLKGENMCkvlVIDCRPHSVFEENNInfPSCINIpselldsGVSAGSI-ERRLNEDTRQIWNRrGEKEFVVLMDESTKVNDITpeCRIQ 312 578899999777655788************99999******88766533333333.3333333333333335555555555555557777754444 PP Rhodanese 82 k......k....lGykn.vyvldGGfeaW 99 + k +k+ +ldGGf +W FUN_001947-T2 313 RlkdvifKfdsnSSLKRePLILDGGFHSW 341 454555514455334555*********99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1322 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1769 (0.0692503); expected 510.9 (0.02) Passed bias filter: 882 (0.0345273); expected 510.9 (0.02) Passed Vit filter: 76 (0.00297514); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.51u 0.39s 00:00:00.90 Elapsed: 00:00:00.42 # Mc/sec: 12644.48 // Query: FUN_001947-T3 [L=1045] Description: FUN_001947 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-36 124.9 0.1 9.3e-36 124.2 0.1 1.3 1 UCH Ubiquitin carboxyl-terminal hydrolase 2.6e-07 31.0 0.5 5.1e-07 30.1 0.5 1.5 1 WW WW domain 4e-07 30.5 0.1 7.2e-07 29.6 0.1 1.4 1 UCH_1 Ubiquitin carboxyl-terminal hydrolase 0.0076 17.1 0.0 0.019 15.9 0.0 1.7 1 Rhodanese Rhodanese-like domain Domain annotation for each model (and alignments): >> UCH Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 124.2 0.1 1.5e-39 9.3e-36 1 145 [. 845 1014 .. 845 1032 .. 0.93 Alignments for each domain: == domain 1 score: 124.2 bits; conditional E-value: 1.5e-39 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 1 vGlkNlgntCymnsvlQaLlsipelrdlllrieeekedseeekei...nllkalaklfkelqkkkksssvkPkklkkllgklneefsgykqqDa 91 +Gl+NlgntCymnsv+Q+L+s+++l+ ++ + + ++ ++++ + +l++ ++ l++ l+ + + ++v+P+++k+++gk++++fsgy+qqD+ FUN_001947-T3 845 TGLRNLGNTCYMNSVVQCLSSVTPLSAFFISGAFREDINRTNRDGtrgELAEIFSVLVRVLH-SGQFKCVSPNEFKRTIGKFKSQFSGYDQQDS 937 7******************************9999999999988855558888888888777.669**************************** PP xxxxxxxxxxxxxxxxx.......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF UCH 92 qEfleflLdqlheklnk.......................wekaskeeeslitdlFrgqlksrlkckeceeeklkik 145 qE+l+fl+d+lhe+lnk we+++ ++ s++++lF g + s++kc c++e+ k++ FUN_001947-T3 938 QELLAFLMDGLHEDLNKvkqkpylkapsddldpetaakiaWENHKMRNASIMVELFDGLFMSTVKCIVCGKESRKFD 1014 ***************************************99******************************977776 PP >> WW WW domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.1 0.5 7.9e-11 5.1e-07 1 31 [] 712 740 .. 712 740 .. 0.97 Alignments for each domain: == domain 1 score: 30.1 bits; conditional E-value: 7.9e-11 WW 1 LPpgWeeawdpdsGrvYYyNhnTgetqWekP 31 LPpgWe+++d + + Y+ +hnT++t+We P FUN_001947-T3 712 LPPGWEKVVDGE--KLYFKDHNTQTTHWEMP 740 8***********..6**************99 PP >> UCH_1 Ubiquitin carboxyl-terminal hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.1 1.1e-10 7.2e-07 2 165 .. 846 1025 .. 845 1042 .. 0.85 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 1.1e-10 UCH_1 2 GLEthiansYtNslLQllrfipplrnlalshlateckke.......ncLlcElgflfdmlekakgkncqasNFlkalssipeasalglleeeee 88 GL + +++Y+Ns++Q+l ++pl + +s + +e+ + L + l++ l+ + k ++ + F +++++++ s++ ++++ FUN_001947-T3 846 GLRNLGNTCYMNSVVQCLSSVTPLSAFFISGAFREDINRtnrdgtrGELAEIFSVLVRVLHSGQFKCVSPNEFKRTIGKFK--SQFSGYDQQD- 936 99****************************999977766677666556666667777999*9**99***************..5555534422. PP UCH_1 89 skkkaslssliqsfnrflleqlsseekstkkns.......................seaeseleqllgikaettirclsCgsesekesstlvld 159 q++ fl++ l+++ +++k+++ +++s + +l+ +t++c+ Cg+es+k + l FUN_001947-T3 937 ----------SQELLAFLMDGLHEDLNKVKQKPylkapsddldpetaakiawenhkMRNASIMVELFDGLFMSTVKCIVCGKESRKFDAFSNLT 1020 ..........38899***************999**********************9888899999*********************99999988 PP UCH_1 160 liypkk 165 l p + FUN_001947-T3 1021 LPLP-S 1025 8444.2 PP >> Rhodanese Rhodanese-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 3e-06 0.019 1 99 [. 83 206 .. 83 208 .. 0.63 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 3e-06 Rhodanese 1 saeelkelledgkvv...liDvRppeeyakghI..pgAvnv.......sltrlslppapllellekllel.dkdktivvycesgnraaaa..aall 81 sa++l+++l+ +++ +iD+Rp + +++ I p+ +n+ +++s ++ l+e +++ ++ +++ +v+ +es + + +++ FUN_001947-T3 83 SAQDLYDMLKGENMCkvlVIDCRPHSVFEENNInfPSCINIpselldsGVSAGSI-ERRLNEDTRQIWNRrGEKEFVVLMDESTKVNDITpeCRIQ 177 578899999777655788************99999******88766533333333.3333333333333335555555555555557777754444 PP Rhodanese 82 k......k....lGykn.vyvldGGfeaW 99 + k +k+ +ldGGf +W FUN_001947-T3 178 RlkdvifKfdsnSSLKRePLILDGGFHSW 206 454555514455334555*********99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1045 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 866 (0.033901); expected 510.9 (0.02) Passed bias filter: 537 (0.0210217); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.44u 0.37s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 10026.38 // Query: FUN_001948-T1 [L=1438] Description: FUN_001948 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-70 238.8 0.4 1.1e-68 232.7 0.4 2.2 1 His_Phos_2 Histidine phosphatase superfamily (branch 2) 9.2e-41 138.4 0.1 1.9e-40 137.4 0.1 1.6 1 PPIP5K2_N Diphosphoinositol pentakisphosphate kinase 2 N-te 2.3e-05 24.6 0.0 7.6e-05 22.9 0.0 1.8 2 RimK RimK-like ATP-grasp domain ------ inclusion threshold ------ 1 9.8 0.0 1 9.8 0.0 3.0 3 DUF883 DUF883 N-terminal domain Domain annotation for each model (and alignments): >> His_Phos_2 Histidine phosphatase superfamily (branch 2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 232.7 0.4 1.7e-72 1.1e-68 1 354 [] 374 962 .. 374 962 .. 0.88 Alignments for each domain: == domain 1 score: 232.7 bits; conditional E-value: 1.7e-72 His_Phos_2 1 eleqvqvvsRHGdRtPtqkkkkeveslifkllse...............................................lagslegklsflgty 49 el++v+ ++RHGdRtP+qk+k+ev++++f+ l++ l+ +le+++ f+g++ FUN_001948-T1 374 ELRCVVGIIRHGDRTPKQKMKMEVRHPRFIELFKkyngfdehklklkrpaqlqevldiardllagikegmpvfesrnkihqLKSVLEMYGYFSGIN 469 79*******************************************************************************888888888888888 PP His_Phos_2 50 rk.............................................................................................. 51 rk FUN_001948-T1 470 RKiqfkylgkardgtdsessgdhqtgdsgpdektvkrklqgketkevkakqaadskdesdqakkhnmeenkktspakdakdsegispdvnekkvlt 565 88888888888888888888888888888888888888888888888888888888888888888888888899999999999999********** PP His_Phos_2 52 ...eklqytlkwgg.ltpaGrkqaeelGrqfrqrYv............eLlrneltq.kdlkirasseeRviaSAeafaeGllgaeg......... 121 +l ++lkwgg lt +G++qa+elGr+fr+ Y+ +Llr ++t+ +dlki+as+e+Rv+++A+afa+G+l+ eg FUN_001948-T1 566 dseHSLLLILKWGGeLTTMGKEQALELGRAFRSIYPgghgqysklsgcGLLRLHSTYrHDLKIYASDEGRVQMTAAAFAKGFLALEGeltpilvhl 661 ***********************************************************************************9999********* PP His_Phos_2 122 ...vdkdksllddsnvakviideekkalanlllagy.......escpafes...............iknakrvdealkklkkdlleniakrlskl. 191 +++ ++ld+s a ++ ++k++l+++l +++ + +kn+ ++e l l ++l+ ++ + ++ FUN_001948-T1 662 vrsDKNTTEMLDTSCDAAKTLGKVKHRLHEMLHSSKdfeeddfV------KlaptksrsvinamksVKNPHAMCERLYDLVQNLTGQLKELIAQKi 751 **966777777777777777777777777777555533333332......1444444566665555666666666666666666666663333337 PP His_Phos_2 192 ........lpgetnltaddvwslldkcffetn.kadlspfcdlfte..edllhney..lkdleelygl............ygignelkktiGgpll 262 ++ et +++ +w++l+k+f +n ++d+s ++d++++ +d++hn++ lk ely++ ygi++ +k+ i++ ++ FUN_001948-T1 752 ydqrdpflYHDETLELMTHRWTKLQKDFKLKNgQFDISLIPDIYDCikYDVQHNSQlaLKNSLELYKCakafadivipqeYGITQDEKLGIAQRVC 847 777888899***9*******************************************4444455599999*************************** PP His_Phos_2 263 nellarlendlqaeke...............atfprdaklylyftHDttiasllsaL...glfdelekesklkvldslkasgevpyaarlvfElye 340 +ll++++ dl+++ + t+ r+++++lyft++++++++l+a+ +lf+ +++ +++++ d+l +e++y++++v++l+e FUN_001948-T1 848 VRLLRKIRGDLRHADKsdihtrlnpnysqhvETPHRHVRTRLYFTSESHVHTVLNAFrygNLFEHIPDDQWQRAVDFLDEVPELNYMTQIVLMLFE 943 **************99******************************************************************************** PP His_Phos_2 341 ......csseedryvrllln 354 c se++++v+++++ FUN_001948-T1 944 dpkadpC-SEKRFHVEVHFS 962 5555444.6666*****986 PP >> PPIP5K2_N Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 137.4 0.1 3e-44 1.9e-40 1 90 [] 39 128 .. 39 128 .. 0.99 Alignments for each domain: == domain 1 score: 137.4 bits; conditional E-value: 3e-44 PPIP5K2_N 1 ikvgvcamekkakskpmkeilerlkefeelevvvfeeevileepveeWPvvdvlisfyskgfPlekaieYvklrkpflindleaqelllD 90 i++g+cam+kk++s+pm+eil r++ f+ l+++vf++e+il++pve WP++d+lisfyskgfPlekaieY+klrkpf +ndl++q+ l+D FUN_001948-T1 39 IRIGICAMSKKTNSQPMQEILGRMSVFDCLDIIVFSDETILNDPVEAWPICDCLISFYSKGFPLEKAIEYAKLRKPFSLNDLDMQYALMD 128 89**************************************************************************************98 PP >> RimK RimK-like ATP-grasp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.3 8.2e+03 9 29 .. 134 154 .. 131 186 .. 0.74 2 ! 22.9 0.0 1.2e-08 7.6e-05 78 175 .. 232 330 .. 207 341 .. 0.82 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.3 RimK 9 klLakakikvpntalardeed 29 lLa a+i++p+ a+ +e+ FUN_001948-T1 134 SLLASAGIDTPRHAILLRDEN 154 588888888888877655554 PP == domain 2 score: 22.9 bits; conditional E-value: 1.2e-08 RimK 78 vqeyieeaenediRvlvvddevvaalerva..keGdFRsnlhrGgvaeklslseeekelAikaakameldvaGvDllrakrgllvlEvnsspglek 171 +++ ++++d++v v+ e a r++ +G +++ + ++ l++ ekelA k+ k+ + v+G Dllr++ +v++vn ++ FUN_001948-T1 232 YEDFVV-TDGTDVKVYTVGPEYAHAEARKSpsLDGKVERDCQGKEIRYPVILNQYEKELANKVCKLFKQTVCGCDLLRTHGKSFVCDVNGFSFVKT 326 555554.4678999999999998887776522689999999988999999***************************************9888888 PP RimK 172 iekt 175 ++k+ FUN_001948-T1 327 SKKY 330 7665 PP >> DUF883 DUF883 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.22 1.4e+03 34 49 .. 423 438 .. 423 442 .. 0.83 2 ? -3.3 1.5 2 1.2e+04 15 34 .. 514 533 .. 511 533 .. 0.77 3 ? 9.8 0.0 0.00016 1 14 45 .. 668 698 .. 666 698 .. 0.90 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.22 DUF883 34 erlesrLkraRdrlsd 49 ++l++ L+ aRd l++ FUN_001948-T1 423 AQLQEVLDIARDLLAG 438 589999******9976 PP == domain 2 score: -3.3 bits; conditional E-value: 2 DUF883 15 eeLLksaadeageeadeLRe 34 e+ + a+++++e d++++ FUN_001948-T1 514 KEVKAKQAADSKDESDQAKK 533 56777779999999999985 PP == domain 3 score: 9.8 bits; conditional E-value: 0.00016 DUF883 14 leeLLksaadeageeadeLRerlesrLkraRd 45 + e+L +++ +a +++ +++ rl+++L++ +d FUN_001948-T1 668 TTEML-DTSCDAAKTLGKVKHRLHEMLHSSKD 698 67888.7799******************9987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1438 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1356 (0.0530828); expected 510.9 (0.02) Passed bias filter: 608 (0.0238011); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.54u 0.39s 00:00:00.93 Elapsed: 00:00:00.43 # Mc/sec: 13458.84 // Query: FUN_001949-T1 [L=171] Description: FUN_001949 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 12.8 0.3 0.24 11.9 0.1 1.6 2 DUF4268 Domain of unknown function (DUF4268) Domain annotation for each model (and alignments): >> DUF4268 Domain of unknown function (DUF4268) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 0.26 6.7e+03 113 127 .. 14 28 .. 4 51 .. 0.60 2 ? 11.9 0.1 9.5e-06 0.24 17 63 .. 93 139 .. 82 163 .. 0.85 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 0.26 DUF4268 113 nkedWpeiieflkek 127 + +dW++ i ++ FUN_001949-T1 14 DVQDWEDKITSGQSE 28 444555444433333 PP == domain 2 score: 11.9 bits; conditional E-value: 9.5e-06 DUF4268 17 klfsnvkpskrkWlnystgisgvsfkliadkkkarvelyiehkdeee 63 ++++p++r+W + +tg+ ++fk + +ka ++l+i++ +e + FUN_001949-T1 93 RVTTHTRPRRRRWNKNDTGVFCLKFKEKTRPGKAAIRLRIGKDNELK 139 4567899*********************************9987755 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (171 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 907 (0.035506); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1688.20 // Query: FUN_001950-T1 [L=1043] Description: FUN_001950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-26 93.1 12.3 4.8e-19 68.8 2.4 5.7 6 USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding ------ inclusion threshold ------ 0.19 12.2 7.6 0.19 12.2 2.3 3.3 3 T2SSF Type II secretion system (T2SS), protein F 0.37 11.3 4.0 0.54 10.8 1.5 2.7 2 HTH_62 Recombinase-like helix-turn-helix domain 0.64 10.5 2.8 2.1 8.7 0.2 3.0 2 LodA_N L-Lysine epsilon oxidase N-terminal 2.5 8.8 5.6 1.5 9.6 0.1 3.1 3 DUF6360 Family of unknown function (DUF6360) 4.7 7.7 5.2 5.6 7.4 0.1 3.2 3 HetR_C Heterocyst differentiation regulator C-termin Domain annotation for each model (and alignments): >> USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 2.0 0.14 5.8e+02 2 31 .. 101 130 .. 100 167 .. 0.89 2 ? -4.3 2.2 6 2.6e+04 1 27 [. 365 391 .. 365 393 .. 0.78 3 ! 68.8 2.4 1.1e-22 4.8e-19 2 64 .. 604 666 .. 603 667 .. 0.98 4 ? -1.7 0.0 1.1 4.6e+03 1 12 [. 781 792 .. 781 800 .. 0.86 5 ? -4.7 1.9 6 2.6e+04 13 57 .. 828 872 .. 827 875 .. 0.66 6 ! 38.8 2.4 2.5e-13 1e-09 1 65 [] 944 1010 .. 944 1010 .. 0.97 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.14 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLs 31 L++++++L+ ++L l+l++ q+ eL FUN_001950-T1 101 LTSKVQQLTEERDQLRLSLDQATQERKELI 130 899****************99999887775 PP == domain 2 score: -4.3 bits; conditional E-value: 6 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqs 27 rL+r++ e++ q+++L + ++ qq FUN_001950-T1 365 RLRRKVLEMQDQLKMLHQKSLQHEQQQ 391 789999999999999987777777765 PP == domain 3 score: 68.8 bits; conditional E-value: 1.1e-22 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeayevLlal 64 L++r ++ +aqn+++sl+lee++++++++s+l+gkyEsn+tAL+laL +r++e yevLl l FUN_001950-T1 604 LTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYESNCTALKLALSFADRVIETYEVLLQL 666 899**********************************************************98 PP == domain 4 score: -1.7 bits; conditional E-value: 1.1 USHBP1_PDZ-bd 1 rLqrrieeLkaq 12 rL++ i++Lk+ FUN_001950-T1 781 RLKSYIQQLKSE 792 89********86 PP == domain 5 score: -4.7 bits; conditional E-value: 6 USHBP1_PDZ-bd 13 nevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckea 57 n+vL l k++ +eL ++ E + AL l + ++a FUN_001950-T1 828 NAVLMQELMALKEEKAELKAKNYLVEKEKKALELKITSRDAQEHA 872 677777777778888888777777777777777666655555555 PP == domain 6 score: 38.8 bits; conditional E-value: 2.5e-13 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLe.....yserckeayevLlalv 65 +L++ri eL+ ++e Ls+++e r+qq++e + +l+k++ AL+ a+e + r+ ++++++ +v FUN_001950-T1 944 KLKARINELVDALETLSKNSETRHQQTAEYVADLKKAN---GALVAAYEkakkkHGARLRKLEQQMITMV 1010 7*************************************...***********99999*********9986 PP >> T2SSF Type II secretion system (T2SS), protein F # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.2 2.6 1.1e+04 47 53 .. 118 124 .. 82 162 .. 0.49 2 ? 0.7 0.0 0.16 7e+02 50 99 .. 548 597 .. 523 605 .. 0.84 3 ? 12.2 2.3 4.4e-05 0.19 15 101 .. 952 1040 .. 950 1042 .. 0.89 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 2.6 T2SSF 47 slseale 53 sl++a + FUN_001950-T1 118 SLDQATQ 124 2222222 PP == domain 2 score: 0.7 bits; conditional E-value: 0.16 T2SSF 50 ealertpssefpdlliqliaagesggnLaevLerladyleeerelrrkik 99 +al++ p+ +++ + li+a e+ + +v+++l y++ +++ + k + FUN_001950-T1 548 RALSQLPEFSSSKMPSDLIRALETCRTIQDVFKALFSYCDTQADKKLKEY 597 68888887555999999**************9999999999999998865 PP == domain 3 score: 12.2 bits; conditional E-value: 4.4e-05 T2SSF 15 lleaLeilaeeaengplreelkriaervreGgslseale....rtpssefpdlliqliaagesggnLaevLerladyleeerelrrkikaa 101 l++aLe+l++++ + ++++ ++ +a+ ++ g l +a e +++ +++l +q+i++ e++ +++ +lee++++ ++ + FUN_001950-T1 952 LVDALETLSKNS-ETRHQQTAEYVADLKKANGALVAAYEkakkKHG-ARLRKLEQQMITMVERHDAQVRTMKERISLLEEQLKTTTARQNE 1040 89**********.999999999999999999999999998875555.599********************************998877765 PP >> HTH_62 Recombinase-like helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 1.5 0.00013 0.54 7 48 .. 121 161 .. 53 169 .. 0.90 2 ? -3.2 0.0 3 1.3e+04 41 59 .. 736 755 .. 731 758 .. 0.64 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00013 HTH_62 7 ephQtRsreptaYEdlLadaleraFaagaheLpelVagLNaa 48 ++ Q R++ + +YEd+L+ + + ++ ++eL++++a LN++ FUN_001950-T1 121 QATQERKELIHDYEDRLSSQATQS-EQHITELQSVIAELNKK 161 456***************998886.888************97 PP == domain 2 score: -3.2 bits; conditional E-value: 3 HTH_62 41 lVagLNaa.glrspdGepWt 59 l ++L ++ + +s G+pW FUN_001950-T1 736 LLQKLDRNlETQSSGGQPWE 755 55566543155677999997 PP >> LodA_N L-Lysine epsilon oxidase N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.2 0.0005 2.1 76 146 .. 15 85 .. 12 100 .. 0.76 2 ? 0.6 0.3 0.16 6.6e+02 77 149 .. 92 166 .. 85 211 .. 0.56 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0005 LodA_N 76 lankKaawyefeealdipeaakakasklrnakvtgadrkkLvidpgprsisgrskeeakfdsgsflekevk 146 an+K+ + f+++++i+ a++ ++ + + + ++ ++L idp+ ++i + ++++ + +s +fle +++ FUN_001950-T1 15 QANEKSIVSGFNSMEEIGGAKTNEKANGKESWEIDSGTQELNIDPTIQQIMSVANSKGQTRSSNFLELANT 85 59****************9999665555544444688999************9988888888888853222 PP == domain 2 score: 0.6 bits; conditional E-value: 0.16 LodA_N 77 ankKaawyefeealdipeaakakasklrna.kvtgadrkkLvidpgprsisgrskeeakfdsgsfl..e..kevkLGe 149 a K + e++++ ++ + ++ +lr + + ++++rk+L+ d + r s+++++e+++++ + + e k+ +L++ FUN_001950-T1 92 ASLKTEIVELTSKV---QQLTEERDQLRLSlDQATQERKELIHDYEDRLSSQATQSEQHITELQSViaElnKKLSLAS 166 44444444444333...2222233444443033458999999999998888877777666543332233113344443 PP >> DUF6360 Family of unknown function (DUF6360) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.27 1.2e+03 56 82 .. 103 129 .. 94 139 .. 0.76 2 ? -3.9 0.3 5.3 2.3e+04 36 68 .. 235 267 .. 223 280 .. 0.63 3 ? 9.6 0.1 0.00035 1.5 34 90 .. 582 640 .. 570 641 .. 0.80 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.27 DUF6360 56 tdldeveahadkvslsaaqarelaael 82 +++++++ d++ ls +qa + +el FUN_001950-T1 103 SKVQQLTEERDQLRLSLDQATQERKEL 129 4688899999*********98777776 PP == domain 2 score: -3.9 bits; conditional E-value: 5.3 DUF6360 36 vttdsrddpdavelqvemdntdldeveahadkv 68 +t++s+++ d ++ e +n l+ +++ a +v FUN_001950-T1 235 MTAESQQEEDIKPVEKENENKPLHSLQSLAKTV 267 455555555555556666666666666655555 PP == domain 3 score: 9.6 bits; conditional E-value: 0.00035 DUF6360 34 lnvttdsrddpd..avelqvemdntdldeveahadkvslsaaqarelaaelekyagrve 90 l d++ d + el++em + d+++a + +sls +++r+ a+ + g+ e FUN_001950-T1 582 LFSYCDTQADKKlkEYELEIEMLTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYE 640 5555666666641157899*****************************99988777766 PP >> HetR_C Heterocyst differentiation regulator C-terminal Hood domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.1 0.0013 5.6 24 65 .. 99 140 .. 89 156 .. 0.86 2 ? 0.8 0.0 0.16 6.7e+02 30 54 .. 328 352 .. 307 357 .. 0.78 3 ? -2.5 0.3 1.7 7.1e+03 30 55 .. 1006 1031 .. 998 1040 .. 0.51 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0013 HetR_C 24 aerkakvlrlleeldilpekleealeeldeiirawadkyhqe 65 e +kv +l ee d l l++a +e e+i ++ d+ + FUN_001950-T1 99 VELTSKVQQLTEERDQLRLSLDQATQERKELIHDYEDRLSSQ 140 567789999****************************97655 PP == domain 2 score: 0.8 bits; conditional E-value: 0.16 HetR_C 30 vlrlleeldilpekleealeeldei 54 + ++ e dil kl+++ +el++i FUN_001950-T1 328 AQAVISERDILKGKLKKTESELEQI 352 55688999*************9987 PP == domain 3 score: -2.5 bits; conditional E-value: 1.7 HetR_C 30 vlrlleeldilpekleealeeldeii 55 ++ ++e d ++e ++ l+e + FUN_001950-T1 1006 MITMVERHDAQVRTMKERISLLEEQL 1031 34444444444444444444444433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1043 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3600 (0.140928); expected 510.9 (0.02) Passed bias filter: 824 (0.0322568); expected 510.9 (0.02) Passed Vit filter: 124 (0.00485418); expected 25.5 (0.001) Passed Fwd filter: 66 (0.00258368); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.75u 0.44s 00:00:01.19 Elapsed: 00:00:00.43 # Mc/sec: 9876.20 // Query: FUN_001950-T2 [L=1117] Description: FUN_001950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-26 92.7 12.3 5.2e-19 68.7 2.4 5.6 6 USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding 0.0079 16.7 3.0 0.21 12.1 2.3 3.4 2 T2SSF Type II secretion system (T2SS), protein F ------ inclusion threshold ------ 0.11 13.2 1.0 1.6 9.4 0.1 3.1 2 DUF6360 Family of unknown function (DUF6360) 0.2 12.2 3.0 0.46 11.0 1.2 2.8 2 HTH_62 Recombinase-like helix-turn-helix domain 4 7.9 5.0 6.1 7.3 0.1 3.4 3 HetR_C Heterocyst differentiation regulator C-termin Domain annotation for each model (and alignments): >> USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 2.0 0.12 6.3e+02 2 31 .. 175 204 .. 174 241 .. 0.89 2 ? -4.4 2.2 5 2.6e+04 1 27 [. 439 465 .. 439 467 .. 0.78 3 ! 68.7 2.4 1e-22 5.2e-19 2 64 .. 678 740 .. 677 741 .. 0.98 4 ? -1.8 0.0 0.97 4.9e+03 1 12 [. 855 866 .. 855 874 .. 0.86 5 ? -4.8 1.7 5 2.6e+04 13 49 .. 902 938 .. 901 948 .. 0.63 6 ! 38.7 2.4 2.2e-13 1.1e-09 1 65 [] 1018 1084 .. 1018 1084 .. 0.97 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.12 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLs 31 L++++++L+ ++L l+l++ q+ eL FUN_001950-T2 175 LTSKVQQLTEERDQLRLSLDQATQERKELI 204 899****************99999887775 PP == domain 2 score: -4.4 bits; conditional E-value: 5 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqs 27 rL+r++ e++ q+++L + ++ qq FUN_001950-T2 439 RLRRKVLEMQDQLKMLHQKSLQHEQQQ 465 789999999999999987777777765 PP == domain 3 score: 68.7 bits; conditional E-value: 1e-22 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeayevLlal 64 L++r ++ +aqn+++sl+lee++++++++s+l+gkyEsn+tAL+laL +r++e yevLl l FUN_001950-T2 678 LTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYESNCTALKLALSFADRVIETYEVLLQL 740 899**********************************************************98 PP == domain 4 score: -1.8 bits; conditional E-value: 0.97 USHBP1_PDZ-bd 1 rLqrrieeLkaq 12 rL++ i++Lk+ FUN_001950-T2 855 RLKSYIQQLKSE 866 89********86 PP == domain 5 score: -4.8 bits; conditional E-value: 5 USHBP1_PDZ-bd 13 nevLsltleerkqqseeLslllgkyEsnatALrlaLe 49 n+vL l k++ +eL ++ E + AL l FUN_001950-T2 902 NAVLMQELMALKEEKAELKAKNYLVEKEKKALELKIT 938 6677777777777777777666666666666666555 PP == domain 6 score: 38.7 bits; conditional E-value: 2.2e-13 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLe.....yserckeayevLlalv 65 +L++ri eL+ ++e Ls+++e r+qq++e + +l+k++ AL+ a+e + r+ ++++++ +v FUN_001950-T2 1018 KLKARINELVDALETLSKNSETRHQQTAEYVADLKKAN---GALVAAYEkakkkHGARLRKLEQQMITMV 1084 7*************************************...***********99999*********9986 PP >> T2SSF Type II secretion system (T2SS), protein F # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.15 7.6e+02 50 99 .. 622 671 .. 597 679 .. 0.84 2 ! 12.1 2.3 4e-05 0.21 15 101 .. 1026 1114 .. 1024 1116 .. 0.89 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.15 T2SSF 50 ealertpssefpdlliqliaagesggnLaevLerladyleeerelrrkik 99 +al++ p+ +++ + li+a e+ + +v+++l y++ +++ + k + FUN_001950-T2 622 RALSQLPEFSSSKMPSDLIRALETCRTIQDVFKALFSYCDTQADKKLKEY 671 68888887555999999*************99999999999999998865 PP == domain 2 score: 12.1 bits; conditional E-value: 4e-05 T2SSF 15 lleaLeilaeeaengplreelkriaervreGgslseale....rtpssefpdlliqliaagesggnLaevLerladyleeerelrrkikaa 101 l++aLe+l++++ + ++++ ++ +a+ ++ g l +a e +++ +++l +q+i++ e++ +++ +lee++++ ++ + FUN_001950-T2 1026 LVDALETLSKNS-ETRHQQTAEYVADLKKANGALVAAYEkakkKHG-ARLRKLEQQMITMVERHDAQVRTMKERISLLEEQLKTTTARQNE 1114 89**********.999999999999999999999999998875555.599********************************998877765 PP >> DUF6360 Family of unknown function (DUF6360) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.1 0.25 1.3e+03 56 82 .. 177 203 .. 168 213 .. 0.76 2 ? 9.4 0.1 0.00031 1.6 34 90 .. 656 714 .. 644 715 .. 0.80 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.25 DUF6360 56 tdldeveahadkvslsaaqarelaael 82 +++++++ d++ ls +qa + +el FUN_001950-T2 177 SKVQQLTEERDQLRLSLDQATQERKEL 203 4688899999*********98777776 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00031 DUF6360 34 lnvttdsrddpd..avelqvemdntdldeveahadkvslsaaqarelaaelekyagrve 90 l d++ d + el++em + d+++a + +sls +++r+ a+ + g+ e FUN_001950-T2 656 LFSYCDTQADKKlkEYELEIEMLTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYE 714 5555666666641157899*****************************99988777766 PP >> HTH_62 Recombinase-like helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 1.2 8.9e-05 0.46 7 48 .. 195 235 .. 128 243 .. 0.90 2 ? -3.5 0.0 3.1 1.6e+04 49 59 .. 819 829 .. 806 832 .. 0.64 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 8.9e-05 HTH_62 7 ephQtRsreptaYEdlLadaleraFaagaheLpelVagLNaa 48 ++ Q R++ + +YEd+L+ + + ++ ++eL++++a LN++ FUN_001950-T2 195 QATQERKELIHDYEDRLSSQATQS-EQHITELQSVIAELNKK 235 456***************998886.888************97 PP == domain 2 score: -3.5 bits; conditional E-value: 3.1 HTH_62 49 glrspdGepWt 59 + +s G+pW FUN_001950-T2 819 ETQSSGGQPWE 829 45677999997 PP >> HetR_C Heterocyst differentiation regulator C-terminal Hood domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.1 0.0012 6.1 24 65 .. 173 214 .. 163 230 .. 0.86 2 ? 0.7 0.0 0.14 7.2e+02 30 54 .. 402 426 .. 381 431 .. 0.78 3 ? -2.6 0.2 1.5 7.8e+03 30 54 .. 1080 1104 .. 1073 1114 .. 0.49 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0012 HetR_C 24 aerkakvlrlleeldilpekleealeeldeiirawadkyhqe 65 e +kv +l ee d l l++a +e e+i ++ d+ + FUN_001950-T2 173 VELTSKVQQLTEERDQLRLSLDQATQERKELIHDYEDRLSSQ 214 567789999****************************97655 PP == domain 2 score: 0.7 bits; conditional E-value: 0.14 HetR_C 30 vlrlleeldilpekleealeeldei 54 + ++ e dil kl+++ +el++i FUN_001950-T2 402 AQAVISERDILKGKLKKTESELEQI 426 55688999*************9987 PP == domain 3 score: -2.6 bits; conditional E-value: 1.5 HetR_C 30 vlrlleeldilpekleealeeldei 54 ++ ++e d ++e ++ l+e FUN_001950-T2 1080 MITMVERHDAQVRTMKERISLLEEQ 1104 3444444444444444444444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1117 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2971 (0.116305); expected 510.9 (0.02) Passed bias filter: 609 (0.0238403); expected 510.9 (0.02) Passed Vit filter: 108 (0.00422783); expected 25.5 (0.001) Passed Fwd filter: 58 (0.0022705); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.74u 0.40s 00:00:01.14 Elapsed: 00:00:00.42 # Mc/sec: 10636.35 // Query: FUN_001950-T3 [L=809] Description: FUN_001950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.1e-27 94.3 12.3 3.5e-19 69.2 2.4 4.7 6 USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding d 0.0053 17.2 3.0 0.13 12.7 2.3 3.1 2 T2SSF Type II secretion system (T2SS), protein F Domain annotation for each model (and alignments): >> USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 2.3 1.8 2.3e+04 1 27 [. 131 157 .. 131 159 .. 0.78 2 ! 69.2 2.4 2.7e-23 3.5e-19 2 64 .. 370 432 .. 369 433 .. 0.98 3 ? -1.3 0.0 0.27 3.5e+03 1 12 [. 547 558 .. 547 566 .. 0.86 4 ? -4.3 2.0 2 2.6e+04 13 57 .. 594 638 .. 593 641 .. 0.67 5 ? -3.4 0.0 1.2 1.6e+04 6 14 .. 643 651 .. 642 651 .. 0.84 6 ! 39.3 2.4 6e-14 7.6e-10 1 65 [] 710 776 .. 710 776 .. 0.97 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 1.8 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqs 27 rL+r++ e++ q+++L + ++ qq FUN_001950-T3 131 RLRRKVLEMQDQLKMLHQKSLQHEQQQ 157 789999999999999987777777765 PP == domain 2 score: 69.2 bits; conditional E-value: 2.7e-23 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeayevLlal 64 L++r ++ +aqn+++sl+lee++++++++s+l+gkyEsn+tAL+laL +r++e yevLl l FUN_001950-T3 370 LTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYESNCTALKLALSFADRVIETYEVLLQL 432 899**********************************************************98 PP == domain 3 score: -1.3 bits; conditional E-value: 0.27 USHBP1_PDZ-bd 1 rLqrrieeLkaq 12 rL++ i++Lk+ FUN_001950-T3 547 RLKSYIQQLKSE 558 89********86 PP == domain 4 score: -4.3 bits; conditional E-value: 2 USHBP1_PDZ-bd 13 nevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckea 57 n+vL l k++ +eL ++ E + AL l + ++a FUN_001950-T3 594 NAVLMQELMALKEEKAELKAKNYLVEKEKKALELKITSRDAQEHA 638 677777777778888888777777777777777666655555555 PP == domain 5 score: -3.4 bits; conditional E-value: 1.2 USHBP1_PDZ-bd 6 ieeLkaqne 14 ie+Lk+ ++ FUN_001950-T3 643 IEHLKSEMQ 651 9****9875 PP == domain 6 score: 39.3 bits; conditional E-value: 6e-14 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLe.....yserckeayevLlalv 65 +L++ri eL+ ++e Ls+++e r+qq++e + +l+k++ AL+ a+e + r+ ++++++ +v FUN_001950-T3 710 KLKARINELVDALETLSKNSETRHQQTAEYVADLKKAN---GALVAAYEkakkkHGARLRKLEQQMITMV 776 7*************************************...***********99999*********9986 PP >> T2SSF Type II secretion system (T2SS), protein F # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.039 4.9e+02 50 99 .. 314 363 .. 288 371 .. 0.84 2 ! 12.7 2.3 1.1e-05 0.13 15 101 .. 718 806 .. 716 808 .. 0.89 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.039 T2SSF 50 ealertpssefpdlliqliaagesggnLaevLerladyleeerelrrkik 99 +al++ p+ +++ + li+a e+ + +v+++l y++ +++ + k + FUN_001950-T3 314 RALSQLPEFSSSKMPSDLIRALETCRTIQDVFKALFSYCDTQADKKLKEY 363 68888997555999999**************9999999999999998865 PP == domain 2 score: 12.7 bits; conditional E-value: 1.1e-05 T2SSF 15 lleaLeilaeeaengplreelkriaervreGgslseale....rtpssefpdlliqliaagesggnLaevLerladyleeerelrrkikaa 101 l++aLe+l++++ + ++++ ++ +a+ ++ g l +a e +++ +++l +q+i++ e++ +++ +lee++++ ++ + FUN_001950-T3 718 LVDALETLSKNS-ETRHQQTAEYVADLKKANGALVAAYEkakkKHG-ARLRKLEQQMITMVERHDAQVRTMKERISLLEEQLKTTTARQNE 806 89**********.999999999999999999999999998875555.599********************************998877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (809 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2979 (0.116618); expected 510.9 (0.02) Passed bias filter: 803 (0.0314347); expected 510.9 (0.02) Passed Vit filter: 103 (0.0040321); expected 25.5 (0.001) Passed Fwd filter: 45 (0.0017616); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.60u 0.38s 00:00:00.98 Elapsed: 00:00:00.44 # Mc/sec: 7492.15 // Query: FUN_001950-T4 [L=671] Description: FUN_001950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-27 95.3 12.3 2.7e-19 69.6 2.4 4.1 5 USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding 0.0045 17.4 3.0 0.1 13.0 2.3 2.9 2 T2SSF Type II secretion system (T2SS), protein F ------ inclusion threshold ------ 1.2 8.5 9.3 0.16 11.4 4.8 1.8 2 DUF5098 Domain of unknown function (DUF5098) Domain annotation for each model (and alignments): >> USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.6 2.4 3.2e-23 2.7e-19 2 64 .. 232 294 .. 231 295 .. 0.98 2 ? -1.0 0.0 0.33 2.8e+03 1 12 [. 409 420 .. 409 429 .. 0.86 3 ? -4.1 2.3 3 2.6e+04 13 58 .. 456 501 .. 454 503 .. 0.69 4 ? -3.1 0.0 1.5 1.3e+04 6 14 .. 505 513 .. 504 513 .. 0.84 5 ! 39.6 2.4 7e-14 6e-10 1 65 [] 572 638 .. 572 638 .. 0.97 Alignments for each domain: == domain 1 score: 69.6 bits; conditional E-value: 3.2e-23 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeayevLlal 64 L++r ++ +aqn+++sl+lee++++++++s+l+gkyEsn+tAL+laL +r++e yevLl l FUN_001950-T4 232 LTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYESNCTALKLALSFADRVIETYEVLLQL 294 899**********************************************************98 PP == domain 2 score: -1.0 bits; conditional E-value: 0.33 USHBP1_PDZ-bd 1 rLqrrieeLkaq 12 rL++ i++Lk+ FUN_001950-T4 409 RLKSYIQQLKSE 420 89********96 PP == domain 3 score: -4.1 bits; conditional E-value: 3 USHBP1_PDZ-bd 13 nevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeay 58 n+vL l k++ +eL ++ E + AL l + ++ay FUN_001950-T4 456 NAVLMQELMALKEEKAELKAKNYLVEKEKKALELKITSRDAQEHAY 501 7778888888888888887777777777777777666666555555 PP == domain 4 score: -3.1 bits; conditional E-value: 1.5 USHBP1_PDZ-bd 6 ieeLkaqne 14 ie+Lk+ ++ FUN_001950-T4 505 IEHLKSEMQ 513 9****9875 PP == domain 5 score: 39.6 bits; conditional E-value: 7e-14 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLe.....yserckeayevLlalv 65 +L++ri eL+ ++e Ls+++e r+qq++e + +l+k++ AL+ a+e + r+ ++++++ +v FUN_001950-T4 572 KLKARINELVDALETLSKNSETRHQQTAEYVADLKKAN---GALVAAYEkakkkHGARLRKLEQQMITMV 638 7*************************************...***********99999*********9986 PP >> T2SSF Type II secretion system (T2SS), protein F # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 0.045 3.9e+02 50 99 .. 176 225 .. 150 233 .. 0.84 2 ! 13.0 2.3 1.2e-05 0.1 15 101 .. 580 668 .. 578 670 .. 0.89 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.045 T2SSF 50 ealertpssefpdlliqliaagesggnLaevLerladyleeerelrrkik 99 +al++ p+ +++ + li+a e+ + +v+++l y++ +++ + k + FUN_001950-T4 176 RALSQLPEFSSSKMPSDLIRALETCRTIQDVFKALFSYCDTQADKKLKEY 225 68889997555999999***************999999999999998865 PP == domain 2 score: 13.0 bits; conditional E-value: 1.2e-05 T2SSF 15 lleaLeilaeeaengplreelkriaervreGgslseale....rtpssefpdlliqliaagesggnLaevLerladyleeerelrrkikaa 101 l++aLe+l++++ + ++++ ++ +a+ ++ g l +a e +++ +++l +q+i++ e++ +++ +lee++++ ++ + FUN_001950-T4 580 LVDALETLSKNS-ETRHQQTAEYVADLKKANGALVAAYEkakkKHG-ARLRKLEQQMITMVERHDAQVRTMKERISLLEEQLKTTTARQNE 668 89**********.999999999999999999999999998875555.599********************************998877765 PP >> DUF5098 Domain of unknown function (DUF5098) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.1 0.41 3.5e+03 409 448 .. 205 241 .. 192 255 .. 0.40 2 ? 11.4 4.8 1.9e-05 0.16 73 170 .. 571 668 .. 558 671 .] 0.91 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 0.41 DUF5098 409 dayElffallkknkveeseekfeisdekvvdsdsvekeke 448 d++ f+ +++ + +++ +e + e ++ + + ++ + FUN_001950-T4 205 DVFKALFSYCDT---QADKKLKEYELEIEMLTSRSDHIQA 241 333333333332...2222222222222222222222333 PP == domain 2 score: 11.4 bits; conditional E-value: 1.9e-05 DUF5098 73 kevnellkklndkinelneeeekfekklkellkelkakrdshleAwtegkaDpWltekdLkkalkKylkedeesneelkkevleydkelqslkkky 168 k +++ +++l+d +++l +++e ++++++e++ +lk++ + A+++ k+ ++ +L + + +++ +++ ++k+++ +++l+ + + FUN_001950-T4 571 KKLKARINELVDALETLSKNSETRHQQTAEYVADLKKANGALVAAYEKAKKKHGARLRKLEQQMITMVERHDAQVRTMKERISLLEEQLKTTTARQ 666 57889999*********************************************************************************9998876 PP DUF5098 169 re 170 +e FUN_001950-T4 667 NE 668 65 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (671 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2725 (0.106674); expected 510.9 (0.02) Passed bias filter: 906 (0.0354668); expected 510.9 (0.02) Passed Vit filter: 89 (0.00348405); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.44u 0.41s 00:00:00.85 Elapsed: 00:00:00.42 # Mc/sec: 6462.07 // Query: FUN_001950-T5 [L=1096] Description: FUN_001950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-26 92.8 12.3 5.1e-19 68.7 2.4 5.6 6 USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding ------ inclusion threshold ------ 0.1 13.3 1.0 1.6 9.5 0.1 3.1 2 DUF6360 Family of unknown function (DUF6360) 0.21 12.1 3.1 0.45 11.1 1.2 2.7 2 HTH_62 Recombinase-like helix-turn-helix domain 0.21 12.1 7.6 0.2 12.1 2.3 3.4 3 T2SSF Type II secretion system (T2SS), protein F 3.8 8.0 5.0 6 7.4 0.1 3.4 3 HetR_C Heterocyst differentiation regulator C-termin Domain annotation for each model (and alignments): >> USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 2.0 0.12 6.3e+02 2 31 .. 154 183 .. 153 220 .. 0.89 2 ? -4.4 2.2 5 2.6e+04 1 27 [. 418 444 .. 418 446 .. 0.78 3 ! 68.7 2.4 9.9e-23 5.1e-19 2 64 .. 657 719 .. 656 720 .. 0.98 4 ? -1.7 0.0 0.95 4.8e+03 1 12 [. 834 845 .. 834 853 .. 0.86 5 ? -4.7 1.9 5 2.6e+04 13 57 .. 881 925 .. 880 928 .. 0.66 6 ! 38.8 2.4 2.2e-13 1.1e-09 1 65 [] 997 1063 .. 997 1063 .. 0.97 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.12 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLs 31 L++++++L+ ++L l+l++ q+ eL FUN_001950-T5 154 LTSKVQQLTEERDQLRLSLDQATQERKELI 183 899****************99999887775 PP == domain 2 score: -4.4 bits; conditional E-value: 5 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqs 27 rL+r++ e++ q+++L + ++ qq FUN_001950-T5 418 RLRRKVLEMQDQLKMLHQKSLQHEQQQ 444 789999999999999987777777765 PP == domain 3 score: 68.7 bits; conditional E-value: 9.9e-23 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeayevLlal 64 L++r ++ +aqn+++sl+lee++++++++s+l+gkyEsn+tAL+laL +r++e yevLl l FUN_001950-T5 657 LTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYESNCTALKLALSFADRVIETYEVLLQL 719 899**********************************************************98 PP == domain 4 score: -1.7 bits; conditional E-value: 0.95 USHBP1_PDZ-bd 1 rLqrrieeLkaq 12 rL++ i++Lk+ FUN_001950-T5 834 RLKSYIQQLKSE 845 89********86 PP == domain 5 score: -4.7 bits; conditional E-value: 5 USHBP1_PDZ-bd 13 nevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckea 57 n+vL l k++ +eL ++ E + AL l + ++a FUN_001950-T5 881 NAVLMQELMALKEEKAELKAKNYLVEKEKKALELKITSRDAQEHA 925 677777777778888888777777777777777666655555555 PP == domain 6 score: 38.8 bits; conditional E-value: 2.2e-13 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLe.....yserckeayevLlalv 65 +L++ri eL+ ++e Ls+++e r+qq++e + +l+k++ AL+ a+e + r+ ++++++ +v FUN_001950-T5 997 KLKARINELVDALETLSKNSETRHQQTAEYVADLKKAN---GALVAAYEkakkkHGARLRKLEQQMITMV 1063 7*************************************...***********99999*********9986 PP >> DUF6360 Family of unknown function (DUF6360) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.1 0.24 1.2e+03 56 82 .. 156 182 .. 147 192 .. 0.76 2 ? 9.5 0.1 0.00031 1.6 34 90 .. 635 693 .. 623 694 .. 0.80 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.24 DUF6360 56 tdldeveahadkvslsaaqarelaael 82 +++++++ d++ ls +qa + +el FUN_001950-T5 156 SKVQQLTEERDQLRLSLDQATQERKEL 182 4688899999*********98777776 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00031 DUF6360 34 lnvttdsrddpd..avelqvemdntdldeveahadkvslsaaqarelaaelekyagrve 90 l d++ d + el++em + d+++a + +sls +++r+ a+ + g+ e FUN_001950-T5 635 LFSYCDTQADKKlkEYELEIEMLTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYE 693 5555666666641157899*****************************99988777766 PP >> HTH_62 Recombinase-like helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 1.2 8.8e-05 0.45 7 48 .. 174 214 .. 107 222 .. 0.90 2 ? -3.5 0.0 3.1 1.6e+04 49 59 .. 798 808 .. 785 811 .. 0.64 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8.8e-05 HTH_62 7 ephQtRsreptaYEdlLadaleraFaagaheLpelVagLNaa 48 ++ Q R++ + +YEd+L+ + + ++ ++eL++++a LN++ FUN_001950-T5 174 QATQERKELIHDYEDRLSSQATQS-EQHITELQSVIAELNKK 214 456***************998886.888************97 PP == domain 2 score: -3.5 bits; conditional E-value: 3.1 HTH_62 49 glrspdGepWt 59 + +s G+pW FUN_001950-T5 798 ETQSSGGQPWE 808 45677999997 PP >> T2SSF Type II secretion system (T2SS), protein F # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.2 2.3 1.2e+04 47 53 .. 171 177 .. 135 215 .. 0.49 2 ? 0.6 0.0 0.14 7.4e+02 50 99 .. 601 650 .. 576 658 .. 0.84 3 ? 12.1 2.3 3.9e-05 0.2 15 101 .. 1005 1093 .. 1003 1095 .. 0.89 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 2.3 T2SSF 47 slseale 53 sl++a + FUN_001950-T5 171 SLDQATQ 177 2222222 PP == domain 2 score: 0.6 bits; conditional E-value: 0.14 T2SSF 50 ealertpssefpdlliqliaagesggnLaevLerladyleeerelrrkik 99 +al++ p+ +++ + li+a e+ + +v+++l y++ +++ + k + FUN_001950-T5 601 RALSQLPEFSSSKMPSDLIRALETCRTIQDVFKALFSYCDTQADKKLKEY 650 68888887555999999*************99999999999999998865 PP == domain 3 score: 12.1 bits; conditional E-value: 3.9e-05 T2SSF 15 lleaLeilaeeaengplreelkriaervreGgslseale....rtpssefpdlliqliaagesggnLaevLerladyleeerelrrkikaa 101 l++aLe+l++++ + ++++ ++ +a+ ++ g l +a e +++ +++l +q+i++ e++ +++ +lee++++ ++ + FUN_001950-T5 1005 LVDALETLSKNS-ETRHQQTAEYVADLKKANGALVAAYEkakkKHG-ARLRKLEQQMITMVERHDAQVRTMKERISLLEEQLKTTTARQNE 1093 89**********.999999999999999999999999998875555.599********************************998877765 PP >> HetR_C Heterocyst differentiation regulator C-terminal Hood domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.1 0.0012 6 24 65 .. 152 193 .. 142 209 .. 0.86 2 ? 0.7 0.0 0.14 7.1e+02 30 54 .. 381 405 .. 360 410 .. 0.78 3 ? -2.6 0.2 1.5 7.6e+03 30 55 .. 1059 1084 .. 1052 1093 .. 0.49 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0012 HetR_C 24 aerkakvlrlleeldilpekleealeeldeiirawadkyhqe 65 e +kv +l ee d l l++a +e e+i ++ d+ + FUN_001950-T5 152 VELTSKVQQLTEERDQLRLSLDQATQERKELIHDYEDRLSSQ 193 567789999****************************97655 PP == domain 2 score: 0.7 bits; conditional E-value: 0.14 HetR_C 30 vlrlleeldilpekleealeeldei 54 + ++ e dil kl+++ +el++i FUN_001950-T5 381 AQAVISERDILKGKLKKTESELEQI 405 55688999*************9987 PP == domain 3 score: -2.6 bits; conditional E-value: 1.5 HetR_C 30 vlrlleeldilpekleealeeldeii 55 ++ ++e d ++e ++ l+e + FUN_001950-T5 1059 MITMVERHDAQVRTMKERISLLEEQL 1084 34444444444444444444444433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1096 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2923 (0.114426); expected 510.9 (0.02) Passed bias filter: 587 (0.0229791); expected 510.9 (0.02) Passed Vit filter: 105 (0.00411039); expected 25.5 (0.001) Passed Fwd filter: 59 (0.00230965); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.71u 0.42s 00:00:01.12 Elapsed: 00:00:00.44 # Mc/sec: 10140.16 // Query: FUN_001950-T6 [L=783] Description: FUN_001950 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-27 94.5 12.3 3.3e-19 69.3 2.4 4.7 6 USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding d Domain annotation for each model (and alignments): >> USHBP1_PDZ-bd Harmonin-binding protein USHBP1, PDZ-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 2.3 0.87 2.2e+04 1 27 [. 131 157 .. 131 159 .. 0.78 2 ! 69.3 2.4 1.3e-23 3.3e-19 2 64 .. 370 432 .. 369 433 .. 0.98 3 ? -1.2 0.0 0.13 3.4e+03 1 12 [. 547 558 .. 547 566 .. 0.86 4 ? -4.4 2.3 1 2.6e+04 13 58 .. 594 639 .. 592 641 .. 0.69 5 ? -3.3 0.0 0.59 1.5e+04 6 14 .. 643 651 .. 642 651 .. 0.84 6 ! 39.3 2.4 2.9e-14 7.3e-10 1 65 [] 710 776 .. 710 776 .. 0.97 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 0.87 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqs 27 rL+r++ e++ q+++L + ++ qq FUN_001950-T6 131 RLRRKVLEMQDQLKMLHQKSLQHEQQQ 157 789999999999999987777777765 PP == domain 2 score: 69.3 bits; conditional E-value: 1.3e-23 USHBP1_PDZ-bd 2 LqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeayevLlal 64 L++r ++ +aqn+++sl+lee++++++++s+l+gkyEsn+tAL+laL +r++e yevLl l FUN_001950-T6 370 LTSRSDHIQAQNNMISLSLEESRNNADRMSVLVGKYESNCTALKLALSFADRVIETYEVLLQL 432 899**********************************************************98 PP == domain 3 score: -1.2 bits; conditional E-value: 0.13 USHBP1_PDZ-bd 1 rLqrrieeLkaq 12 rL++ i++Lk+ FUN_001950-T6 547 RLKSYIQQLKSE 558 89********86 PP == domain 4 score: -4.4 bits; conditional E-value: 1 USHBP1_PDZ-bd 13 nevLsltleerkqqseeLslllgkyEsnatALrlaLeyserckeay 58 n+vL l k++ +eL ++ E + AL l + ++ay FUN_001950-T6 594 NAVLMQELMALKEEKAELKAKNYLVEKEKKALELKITSRDAQEHAY 639 7778888888888888887777777777777777666655555555 PP == domain 5 score: -3.3 bits; conditional E-value: 0.59 USHBP1_PDZ-bd 6 ieeLkaqne 14 ie+Lk+ ++ FUN_001950-T6 643 IEHLKSEMQ 651 9****9875 PP == domain 6 score: 39.3 bits; conditional E-value: 2.9e-14 USHBP1_PDZ-bd 1 rLqrrieeLkaqnevLsltleerkqqseeLslllgkyEsnatALrlaLe.....yserckeayevLlalv 65 +L++ri eL+ ++e Ls+++e r+qq++e + +l+k++ AL+ a+e + r+ ++++++ +v FUN_001950-T6 710 KLKARINELVDALETLSKNSETRHQQTAEYVADLKKAN---GALVAAYEkakkkHGARLRKLEQQMITMV 776 7*************************************...***********99999*********9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (783 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2708 (0.106009); expected 510.9 (0.02) Passed bias filter: 758 (0.0296731); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 38 (0.00148757); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.55u 0.38s 00:00:00.93 Elapsed: 00:00:00.44 # Mc/sec: 7226.23 // Query: FUN_001951-T1 [L=87] Description: FUN_001951 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (87 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 387 (0.0151497); expected 510.9 (0.02) Passed bias filter: 329 (0.0128792); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.34s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 886.97 // Query: FUN_001952-T1 [L=1013] Description: FUN_001952 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-93 312.6 7.1 7.2e-93 312.0 7.1 1.3 1 ERAP1_C ERAP1-like C-terminal domain 3e-85 285.7 0.4 5.3e-85 284.9 0.4 1.4 1 Peptidase_M1 Peptidase family M1 domain 1.7e-46 159.2 1.4 3.2e-46 158.3 1.4 1.5 1 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.22 11.9 0.0 0.67 10.3 0.0 1.7 1 SprT-like SprT-like family Domain annotation for each model (and alignments): >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 312.0 7.1 1.1e-96 7.2e-93 1 317 [. 673 990 .. 673 991 .. 0.96 Alignments for each domain: == domain 1 score: 312.0 bits; conditional E-value: 1.1e-96 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlksllsedp 94 w+k N ++ Gyyrv+Y+++++++li+ql + v++++dR +liddaf+larag+l++s al +v yl++Et yv+w++al++l+ l ++l d FUN_001952-T1 673 WIKGNFGQVGYYRVHYEDDNWQALIAQLDsdPMVFTAADRSSLIDDAFSLARAGYLKYSIALGTVG-YLEKETRYVPWETALNSLGFLGDIL-GDR 766 9*************************9889999********************************6.99***********************.777 PP ERAP1_C 95 .vyealkaflrkllsplleklgweekpgeshldqqlrslllsaacsagdeevvaeakklfeawlegddsaippdlrwavlcaavanggeaewdall 189 ++ +++f+r+ ++ l++klgw++++++sh +++lrs++l+aac++gd++++++a+++f++w++g+ s+i+ dlr+ v+ +++an g +ew++l+ FUN_001952-T1 767 lGNGYFQKFVRSKVKGLADKLGWKDQKNDSHINKYLRSSILRAACRSGDADALSNATQMFKEWKSGQRSEIDVDLRTLVYYYGIANTGLDEWQWLF 862 7999*******************88889**************************************9988************************** PP ERAP1_C 190 erykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlaglasnpagrelawdfvkenwdelekrlgggs.slgrlvkgltpsf 284 +++ +tt+asek ++++ala + + ++l+ +l+++lds+++r+qd+ +v++++asnp+g+ law+fv++nw++l +++++++ l +l +g+t+ f FUN_001952-T1 863 NKFLNTTDASEKSKMMYALAGSSQTWILNTYLAYSLDSSKIRSQDAVSVITYVASNPVGKYLAWNFVQNNWKALFEMFSTSTfRLTSLTSGVTR-F 957 ******************************************************************************9877677888877776.* PP ERAP1_C 285 steeeldeveaFfadkdtpglrralaqaletir 317 ste+el++++aFf+ + +++ a +qa+e+++ FUN_001952-T1 958 STEAELEQMKAFFNRSEAGTSENARKQAIEKTQ 990 *************999888888********987 PP >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 284.9 0.4 8.3e-89 5.3e-85 1 218 [] 376 593 .. 376 593 .. 1.00 Alignments for each domain: == domain 1 score: 284.9 bits; conditional E-value: 8.3e-89 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 yal v k +++++e y+++ Yplpk d++a+pdfs gaMEnwglityre++ll++ +s+e++k++va v+ HElaHqWfGn+V+ kwW+dlwLnE FUN_001952-T1 376 YALGVGKDVITYYEGYYNLGYPLPKQDMIAIPDFSSGAMENWGLITYRETALLFNEGVSAEANKQRVAVVVSHELAHQWFGNIVSPKWWNDLWLNE 471 799999****************************************************************************************** PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfas++eyl++++++p+w+++e++ll++++ ++ D+l+sshpisv v++++ i+++Fd+isY+KG+s++rmle ++g e+f++gl+ Yl+k++++ FUN_001952-T1 472 GFASFVEYLGVNHTHPDWEMMEQFLLSDLQLVFPLDSLASSHPISVDVDHPKKIKQLFDRISYSKGSSIIRMLEGFVGREKFKEGLSYYLRKYAFA 567 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasgkdvkslmdtw 218 na+t+dlw+al e+++ dvk +mdtw FUN_001952-T1 568 NAETKDLWNALGEKAEMDVKTIMDTW 593 ************************** PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 158.3 1.4 5e-50 3.2e-46 2 186 .] 143 339 .. 142 339 .. 0.89 Alignments for each domain: == domain 1 score: 158.3 bits; conditional E-value: 5e-50 Peptidase_M1_N 2 pehYdldlkinlkektfkGsvtitlqlk...natssivlnakelei.........kkvslsaevasesvkvdfkveqkdeekltiklpeslqqts 84 p hYdl l+++l+++tf+G+v+i ++++ + s i ++ k++++ +v+ + +v ++ ++e+ +++ ++++l+++l+ + FUN_001952-T1 143 PIHYDLYLDPDLEMNTFQGNVSILIEVTaksEFMSYILIHIKDMNVtraqvhkvyGDVKSDTTSPGVEVALKRTFEYPENDFFIFELKNDLE-IG 236 89********************9999987667789***********766554333233333333333456777888999999**********.** PP Peptidase_M1_N 85 svtLeieysgelndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpviesekledgkkitkFee 178 ++ + +ey+ ++ l Gly stYt+ kg+k+ +a+T fe+tdARka+PcfDeP++Katf++ i +d+e++alSNmpv +++ l +g+ +F++ FUN_001952-T1 237 KYVVYMEYKSTFSKHLNGLYISTYTNeKGQKRRLATTKFEPTDARKALPCFDEPAMKATFSTVIVHDTEYTALSNMPVYKQQSLPNGRIASHFKK 331 *********************************************************************************************** PP Peptidase_M1_N 179 tpkmstYL 186 +++mstYL FUN_001952-T1 332 SVPMSTYL 339 *******9 PP >> SprT-like SprT-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.00011 0.67 34 73 .. 418 455 .. 405 462 .. 0.87 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00011 SprT-like 34 GrarlkrkeaeIrLsekllkerseeeleetllHEliHaal 73 G ++++ + + ++e + +e +++++ ++ HEl+H ++ FUN_001952-T1 418 GLITYRE--TALLFNEGVSAEANKQRVAVVVSHELAHQWF 455 7777777..9999************************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1013 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1356 (0.0530828); expected 510.9 (0.02) Passed bias filter: 961 (0.0376199); expected 510.9 (0.02) Passed Vit filter: 94 (0.00367978); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.46u 0.40s 00:00:00.86 Elapsed: 00:00:00.41 # Mc/sec: 9928.19 // Query: FUN_001952-T2 [L=906] Description: FUN_001952 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-85 285.9 0.4 4.4e-85 285.2 0.4 1.4 1 Peptidase_M1 Peptidase family M1 domain 8.2e-83 278.9 4.6 1.3e-82 278.3 4.6 1.3 1 ERAP1_C ERAP1-like C-terminal domain 1.8e-46 159.0 2.4 3.3e-46 158.2 2.4 1.4 1 Peptidase_M1_N Peptidase M1 N-terminal domain ------ inclusion threshold ------ 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 ArsP_2 Putative, 10TM heavy-metal exporter 0.11 13.4 0.7 0.22 12.5 0.7 1.5 1 CR_prot_dom_plant Plant cysteine-rich protein domain 0.24 11.8 0.0 0.59 10.5 0.0 1.6 1 SprT-like SprT-like family Domain annotation for each model (and alignments): >> Peptidase_M1 Peptidase family M1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 285.2 0.4 1e-88 4.4e-85 1 218 [] 343 560 .. 343 560 .. 1.00 Alignments for each domain: == domain 1 score: 285.2 bits; conditional E-value: 1e-88 Peptidase_M1 1 yalevtkklleffeeyfkveYplpkldlvalpdfsagaMEnwglityreelllldpeassesdkrsvaeviaHElaHqWfGnlVtmkwWedlwLnE 96 yal v k +++++e y+++ Yplpk d++a+pdfs gaMEnwglityre++ll++ +s+e++k++va v+ HElaHqWfGn+V+ kwW+dlwLnE FUN_001952-T2 343 YALGVGKDVITYYEGYYNLGYPLPKQDMIAIPDFSSGAMENWGLITYRETALLFNEGVSAEANKQRVAVVVSHELAHQWFGNIVSPKWWNDLWLNE 438 799999****************************************************************************************** PP Peptidase_M1 97 gfasyleylildklepewkvseellleevekalaeDalksshpisvevekaseidevFdaisYeKGasllrmlekllgeevfqkglksYlkkfkyk 192 gfas++eyl++++++p+w+++e++ll++++ ++ D+l+sshpisv v++++ i+++Fd+isY+KG+s++rmle ++g e+f++gl+ Yl+k++++ FUN_001952-T2 439 GFASFVEYLGVNHTHPDWEMMEQFLLSDLQLVFPLDSLASSHPISVDVDHPKKIKQLFDRISYSKGSSIIRMLEGFVGREKFKEGLSYYLRKYAFA 534 ************************************************************************************************ PP Peptidase_M1 193 naktedlwdaleeasgkdvkslmdtw 218 na+t+dlw+al e+++ dvk +mdtw FUN_001952-T2 535 NAETKDLWNALGEKAEMDVKTIMDTW 560 ************************** PP >> ERAP1_C ERAP1-like C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 278.3 4.6 3e-86 1.3e-82 1 265 [. 640 905 .. 640 906 .] 0.98 Alignments for each domain: == domain 1 score: 278.3 bits; conditional E-value: 3e-86 ERAP1_C 1 wvklNaddtGyyrvnYdeeslaklieqll..skvlspldRagliddafalaragelstsdaldlvkaylknEteyvvwsaalsqlstlksllsedp 94 w+k N ++ Gyyrv+Y+++++++li+ql + v++++dR +liddaf+larag+l++s al +v yl++Et yv+w++al++l+ l ++l d FUN_001952-T2 640 WIKGNFGQVGYYRVHYEDDNWQALIAQLDsdPMVFTAADRSSLIDDAFSLARAGYLKYSIALGTVG-YLEKETRYVPWETALNSLGFLGDIL-GDR 733 9*************************9889999********************************6.99***********************.777 PP ERAP1_C 95 .vyealkaflrkllsplleklgweekpgeshldqqlrslllsaacsagdeevvaeakklfeawlegddsaippdlrwavlcaavanggeaewdall 189 ++ +++f+r+ ++ l++klgw++++++sh +++lrs++l+aac++gd++++++a+++f++w++g+ s+i+ dlr+ v+ +++an g +ew++l+ FUN_001952-T2 734 lGNGYFQKFVRSKVKGLADKLGWKDQKNDSHINKYLRSSILRAACRSGDADALSNATQMFKEWKSGQRSEIDVDLRTLVYYYGIANTGLDEWQWLF 829 7999*******************88889**************************************9988************************** PP ERAP1_C 190 erykdttsasekeaalralaatpdpellerllelaldsdevrnqdlravlaglasnpagrelawdfvkenwdelek 265 +++ +tt+asek ++++ala + + ++l+ +l+++lds+++r+qd+ +v++++asnp+g+ law+fv++nw++l + FUN_001952-T2 830 NKFLNTTDASEKSKMMYALAGSSQTWILNTYLAYSLDSSKIRSQDAVSVITYVASNPVGKYLAWNFVQNNWKALFE 905 ************************************************************************9976 PP >> Peptidase_M1_N Peptidase M1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 158.2 2.4 7.8e-50 3.3e-46 2 186 .] 110 306 .. 109 306 .. 0.90 Alignments for each domain: == domain 1 score: 158.2 bits; conditional E-value: 7.8e-50 Peptidase_M1_N 2 pehYdldlkinlkektfkGsvtitlqlk...natssivlnakelei.........kkvslsaevasesvkvdfkveqkdeekltiklpeslqqts 84 p hY+ l+++l+++tf+G+vti ++++ + s i ++ +++++ + + + ++v ++ ++e+ +++ ++++l+++l+ + FUN_001952-T2 110 PLHYNFYLDPYLEQNTFQGKVTILIEVTaasEFMSYILIHINDMNVtrakvykqsADTKSDTASPGDEVALKRTFEYPKNDFFIFELEKDLK-VG 203 99*********************999997667789***********887666533222222333346677888999999999*******999.** PP Peptidase_M1_N 85 svtLeieysgelndklaGlykstYtd.kgekkvvavTqfeatdARkafPcfDePsvKatftisikadkeevalSNmpviesekledgkkitkFee 178 ++ + +ey+ +++l Gly stYt+ kge++ +a+T fe+tdARka+PcfDeP++Katf++ i +d+e++alSNmpv +++ l +g+ +F++ FUN_001952-T2 204 KYVVRMEYKSTFSSQLNGLYISTYTNeKGENRRLATTKFEPTDARKALPCFDEPAMKATFSTVIVHDTEYTALSNMPVYKQQSLPNGRIASHFKK 298 *********************************************************************************************** PP Peptidase_M1_N 179 tpkmstYL 186 +++mstYL FUN_001952-T2 299 SVPMSTYL 306 *******9 PP >> ArsP_2 Putative, 10TM heavy-metal exporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 4e-05 0.17 106 230 .. 36 166 .. 25 184 .. 0.66 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 4e-05 ArsP_2 106 kaalivlaiglvvgilsGlvvnaihkedflrpklaeekkk.ss..atkselaktkisklakklWllllvpalilalllafqvdikkllsleeksie 198 + a+i++ai ++vg++sG++ + ++d l ++ ++ ++ ++ +++s ++ t + k+ + W+ + +p i l +f d + + +++ FUN_001952-T2 36 VLAIIIVAIIIFVGVMSGVLSAKKARKDALDEAKRDRRQGsETasSATSATVVTPTEKTGPEPWYKIRLPENIRPLHYNFYLDPYLEQNTFQGKVT 131 4699****************9999999999988887777632232444455578888999999**********99999998885544433344444 PP ArsP_2 199 vi...gavlallslllwalsrkieeekevaseddk 230 ++ +a++ ++s +l ++ ++ +v +++ + FUN_001952-T2 132 ILievTAASEFMSYILIHINDMNVTRAKVYKQSAD 166 43000333334454555555544444444444444 PP >> CR_prot_dom_plant Plant cysteine-rich protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.7 5.1e-05 0.22 17 71 .] 4 62 .. 2 62 .. 0.72 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 5.1e-05 CR_prot_dom_plant 17 erLvgesdtPisdeslsfklGkvtvl......vvavvvlavvilLvialvslCflakkkkk 71 + L+g + + + +e s k G+v+v v+a+++ v i++++ ++s + akk +k FUN_001952-T2 4 KMLIGGNVSGSNSEEQSEKKGQVFVItrnkaiVLAIII--VAIIIFVGVMSGVLSAKKARK 62 5689999999*************985222221334444..445889999998888888766 PP >> SprT-like SprT-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.00014 0.59 34 73 .. 385 422 .. 372 429 .. 0.87 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00014 SprT-like 34 GrarlkrkeaeIrLsekllkerseeeleetllHEliHaal 73 G ++++ + + ++e + +e +++++ ++ HEl+H ++ FUN_001952-T2 385 GLITYRE--TALLFNEGVSAEANKQRVAVVVSHELAHQWF 422 7777777..9999************************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (906 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 966 (0.0378156); expected 510.9 (0.02) Passed bias filter: 721 (0.0282247); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.43u 0.36s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 8724.80 // Query: FUN_001954-T1 [L=182] Description: FUN_001954 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9e-11 42.0 8.2 3.2e-10 40.2 8.2 2.0 1 zf-A20 A20-like zinc finger 1.5e-09 38.3 8.6 1.5e-09 38.3 8.6 1.9 2 zf-AN1 AN1-like Zinc finger ------ inclusion threshold ------ 6 6.5 6.4 7.6 6.2 6.4 1.1 1 Med3 Mediator complex subunit 3 fungal Domain annotation for each model (and alignments): >> zf-A20 A20-like zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.2 8.2 3.8e-14 3.2e-10 1 24 [] 12 35 .. 12 35 .. 0.97 Alignments for each domain: == domain 1 score: 40.2 bits; conditional E-value: 3.8e-14 zf-A20 1 llCrngCGFfGspateglCSkCYk 24 +lCr gCGF+Gs+ +g+CSkC+k FUN_001954-T1 12 SLCRMGCGFYGSSSSDGMCSKCFK 35 69*********************8 PP >> zf-AN1 AN1-like Zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.6 0.66 5.6e+03 15 20 .. 29 34 .. 18 36 .. 0.67 2 ! 38.3 8.6 1.7e-13 1.5e-09 1 40 [] 123 160 .. 123 160 .. 0.94 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.66 zf-AN1 15 kCkfCg 20 C++C FUN_001954-T1 29 MCSKCF 34 577774 PP == domain 2 score: 38.3 bits; conditional E-value: 1.7e-13 zf-AN1 1 CsfkgCkkkdflp.fkCkfCgkkFClkHrlpedHdCsklek 40 C C+kk++l f+C+ Cg+++C Hr++++HdCs+++k FUN_001954-T1 123 CF--MCRKKVGLTgFECR-CGNVYCGLHRYSDKHDCSFDYK 160 66..4******99*****.*******************997 PP >> Med3 Mediator complex subunit 3 fungal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 6.4 0.0009 7.6 129 200 .. 44 116 .. 35 130 .. 0.73 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.0009 Med3 129 davhskakvvastpsaaaatPtttatPgastktaak.svpaptatatigtptvnnstaaaastatttsstakk 200 +s a+v +stp + P t+ P ++ +a+ +v+ ++t+t++ ++ + a a+t+ ++ k FUN_001954-T1 44 SPNTSAASVMSSTPPGPPEEPCTSHLPASEDLAVAAaEVSPSSSTSTVSVDSDGLRQPEAENEASTSETKDKA 116 445799***********************99877651566667889999888777777777666665555442 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (182 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1161 (0.0454492); expected 510.9 (0.02) Passed bias filter: 458 (0.0179291); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1837.01 // Query: FUN_001955-T1 [L=228] Description: FUN_001955 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (228 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 586 (0.0229399); expected 510.9 (0.02) Passed bias filter: 415 (0.0162458); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2251.00 // Query: FUN_001956-T1 [L=82] Description: FUN_001956 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-32 110.8 4.3 4.3e-32 110.7 4.3 1.0 1 Ost5 Oligosaccharyltransferase subunit 5 0.0014 19.2 0.9 0.0016 19.0 0.9 1.1 1 DUF6512 Family of unknown function (DUF6512) 0.0055 17.4 2.2 0.0058 17.3 2.2 1.1 1 TctB Tripartite tricarboxylate transporter TctB family ------ inclusion threshold ------ 0.11 13.1 1.3 0.12 12.9 1.3 1.0 1 DUF7318 Family of unknown function (DUF7318) Domain annotation for each model (and alignments): >> Ost5 Oligosaccharyltransferase subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.7 4.3 6.7e-36 4.3e-32 2 73 .] 11 82 .] 10 82 .] 0.99 Alignments for each domain: == domain 1 score: 110.7 bits; conditional E-value: 6.7e-36 Ost5 2 pfsppvppsllptlafvllligllltalfflyevtstkskrslikelllalvASlflGfGvvflflavGVYV 73 ++ +p++p+++p+l++vll+ig++++a+ff+yevtstk++r+++kell++lvASlf+GfGv+fl+l+vG+YV FUN_001956-T1 11 RYASPINPAVFPHLTIVLLSIGIFFMAWFFVYEVTSTKYNRDIYKELLVSLVASLFMGFGVLFLLLWVGIYV 82 79*********************************************************************9 PP >> DUF6512 Family of unknown function (DUF6512) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.9 2.5e-07 0.0016 43 99 .. 13 69 .. 5 80 .. 0.77 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 2.5e-07 DUF6512 43 isavnesvwehlklvllpiilwwllyylikgkkynidknkwftgllvalvssiltii 99 s++n +v+ hl +vll i +++ ++++ + ++ + llv+lv+s+++ + FUN_001956-T1 13 ASPINPAVFPHLTIVLLSIGIFFMAWFFVYEVTSTKYNRDIYKELLVSLVASLFMGF 69 589***************977766666666655555566678899999999987644 PP >> TctB Tripartite tricarboxylate transporter TctB family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 2.2 9.2e-07 0.0058 22 93 .. 11 82 .] 1 82 [] 0.62 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 9.2e-07 TctB 22 gtaspvgPgffP....lllgvlllllgllllveaakkeeekeeeredwrkvlklvlallllllayallleplGfll 93 +asp++P++fP +ll+++++++ ++++v + ++ + +r+ +++l ++a l++ + ++ll ++G ++ FUN_001956-T1 11 RYASPINPAVFPhltiVLLSIGIFFM-AWFFV---YEVTSTKYNRDIYKELLVSLVASLFMGFGVLFLLLWVGIYV 82 3449999*****65433357777777.55555...23444555666777777666665555555777999999885 PP >> DUF7318 Family of unknown function (DUF7318) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 1.3 1.9e-05 0.12 10 76 .. 8 75 .. 2 80 .. 0.82 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 1.9e-05 DUF7318 10 dihryepare.staaaiaivlltvvevvfvglftyglvagwglsevgnlflgallavifidlafilll 76 ++ ry + + + ++ivll++ + +f+y ++++ +++ + +l +l+a +f+ +++++ll FUN_001956-T1 8 QMNRYASPINpAVFPHLTIVLLSIGIFFMAWFFVYEVTSTKYNRDIYKELLVSLVASLFMGFGVLFLL 75 56788766551445689******9888888899******99999****************99988766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (82 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1383 (0.0541398); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.34s 00:00:00.63 Elapsed: 00:00:00.41 # Mc/sec: 815.76 // Query: FUN_001957-T1 [L=706] Description: FUN_001957 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-38 130.9 4.4 5.1e-38 129.8 4.4 1.6 1 LbH_EIF2B EIF2B subunit epsilon LbH domain 2.2e-21 76.2 1.6 6.7e-21 74.6 1.6 1.9 1 W2 eIF4-gamma/eIF5/eIF2-epsilon 2.9e-13 50.0 9.7 2.6e-11 43.7 5.7 2.6 2 GMPPB_C GMPPB C-terminal domain 4.9e-10 39.9 0.0 7.9e-10 39.2 0.0 1.3 1 NTP_transferase Nucleotidyl transferase 1.8e-09 37.3 12.5 0.0021 18.2 1.4 4.5 4 Hexapep Bacterial transferase hexapeptide ( 1e-06 29.3 5.3 1.4e-06 28.8 3.4 2.3 1 Hexapep_GlmU GlmU-like, C-terminal hexapeptide 4.3e-05 24.0 6.0 0.088 13.2 0.5 2.8 2 LbH_GLGC GLGC left-handed parallel beta-heli ------ inclusion threshold ------ 0.033 14.3 5.2 1.1 9.3 2.4 3.3 2 DCTN5 Dynactin subunit 5 0.053 13.7 0.7 0.053 13.7 0.7 3.5 4 Hexapep_2 Hexapeptide repeat of succinyl-tran 0.11 11.9 0.5 0.23 10.8 0.5 1.5 1 Fucose_pyrophosphorylase Fucose pyrophosphorylase domain 0.16 12.6 0.2 2.6 8.8 0.0 2.5 2 Ig_NUP210_1st NUP210 Ig-like domain 1 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 TPR_28 GBF1-like, tetratrico peptide repea 0.28 11.8 0.0 0.52 11.0 0.0 1.4 1 NTP_transf_3 MobA-like NTP transferase domain Domain annotation for each model (and alignments): >> LbH_EIF2B EIF2B subunit epsilon LbH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.8 4.4 2.6e-41 5.1e-38 1 104 [. 316 419 .. 316 420 .. 0.98 Alignments for each domain: == domain 1 score: 129.8 bits; conditional E-value: 2.6e-41 LbH_EIF2B 1 rgniYkekdvslarsckieenvviGkgtsigentkisnSviGrnckIgknvkiegsyiwdnvtiednckieksiiadgvvikegvkiekgcvlsfg 96 r+n+Y ++++slar+c +eenv+i kgts+g++t+i+nSviGrnc+Ig+ v+++g ++wdnvt+ed+cki+++i++++v+ik++v+i++g+++sf+ FUN_001957-T1 316 RHNVYLDTELSLARDCILEENVLISKGTSVGAGTVITNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTISSGSLISFN 411 89********************************************************************************************** PP LbH_EIF2B 97 vvvgpnvt 104 vvvgp+++ FUN_001957-T1 412 VVVGPDLV 419 *****976 PP >> W2 eIF4-gamma/eIF5/eIF2-epsilon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.6 1.6 3.4e-24 6.7e-21 2 79 .] 609 690 .. 608 690 .. 0.93 Alignments for each domain: == domain 1 score: 74.6 bits; conditional E-value: 3.4e-24 W2 2 qvdlllaleefcaeseklkklllkilkaLYdlDiveEeailkWwekkssaekg....kkkvrkkakpfvewLeeaeeeseee 79 q+d+l+a+eef+ + + +++l++ +l++LYd++++eE +il+W+ + + + + +kk+r+++ +f++wL+eaeees+ee FUN_001957-T1 609 QRDALNATEEFFLQTMWAAPLFQVFLHMLYDKEVLEESVILQWYLHRRGDISCfepqRKKLRQQISRFITWLQEAEEESDEE 690 89********************************************8876333667789*********************98 PP >> GMPPB_C GMPPB C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.1 3.1e-06 0.0061 3 42 .. 317 356 .. 315 356 .. 0.96 2 ! 43.7 5.7 1.3e-14 2.6e-11 2 93 .. 334 424 .. 333 437 .. 0.90 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 3.1e-06 GMPPB_C 3 gnvlihpsakigegavigpnvvigknvvigegvriknsii 42 nv+++ + + ++++++ nv i+k++++g+g+ i+ns+i FUN_001957-T1 317 HNVYLDTELSLARDCILEENVLISKGTSVGAGTVITNSVI 356 699***********************************98 PP == domain 2 score: 43.7 bits; conditional E-value: 1.3e-14 GMPPB_C 2 ignvlihpsakigegavigpnvvigknvvigegvriknsiilegvkikdhalvkksIiGwkskigkwarieelsvlGedVevkdevlvngai 93 ++nvli++ +++g+g+vi n vig+n+vig+ v ++ + ++v+++d + ++++I+ ++ +i++ + i++ s+++ +V v +++++ + FUN_001957-T1 334 EENVLISKGTSVGAGTVI-TNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTISSGSLISFNVVVGPDLVLQPGV 424 689***************.7999************************************************************999998544 PP >> NTP_transferase Nucleotidyl transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.2 0.0 4e-13 7.9e-10 2 129 .. 25 153 .. 24 170 .. 0.86 Alignments for each domain: == domain 1 score: 39.2 bits; conditional E-value: 4e-13 NTP_transferase 2 aiILaGGsGtRLwPLTrtlakplvpvldkeplidytlsrllnagieeiiviltqekseeveellkdgskfg.....veityalepegkgtAdAv 90 a+IL+ R+ P+T + + l+p ++ pl+dyt++ l++ag++e i++ + ++ +v++++++ + ++ ++++ ++ + dA+ FUN_001957-T1 25 AVILSDSFNFRFLPITLETPRVLLPLVNV-PLLDYTIEFLVEAGVQE-IFVFCSAHADQVKKHISQSK-WTgarspCDVKTIVVEDCFSVGDAL 115 6788888888*******************.*****************.999999***********987.5558888888888888888999999 PP NTP_transferase 91 alaaefledekslvlvLggDhlikddleeavkkakekaa 129 +++ +++ ++ ++gD++ +++le++++++ke+ + FUN_001957-T1 116 REIDRQSLLKSD-FVLVSGDVVSNMKLEQVFQEHKERRN 153 999877777776.999********************987 PP >> Hexapep Bacterial transferase hexapeptide (six repeats) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.0 1.9 0.00019 0.38 2 27 .. 337 361 .. 330 361 .. 0.67 2 ! 18.2 1.4 1.1e-06 0.0021 1 29 [. 359 386 .. 353 387 .. 0.69 3 ! 14.9 0.9 1.2e-05 0.023 1 34 [. 376 408 .. 376 410 .. 0.95 4 ! 6.1 0.0 0.0069 14 3 22 .. 407 426 .. 405 428 .. 0.78 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00019 Hexapep 2 tvIGdnvkIgpnvvigggvvIGdnvi 27 + I +++ +g+++vi + vIG+n++ FUN_001957-T1 337 VLISKGTSVGAGTVI-TNSVIGRNCV 361 556677777777777.6666777775 PP == domain 2 score: 18.2 bits; conditional E-value: 1.1e-06 Hexapep 1 gtvIGdnvkIgpnvvigggvvIGdnviIg 29 ++vIGd v+++ +v++ ++v++ d+++I FUN_001957-T1 359 NCVIGDSVQLD-GVHLWDNVTVEDGCKIS 386 45666666666.88888888888888885 PP == domain 3 score: 14.9 bits; conditional E-value: 1.2e-05 Hexapep 1 gtvIGdnvkIgpnvvigggvvIGdnviIgagvvi 34 +++++d++kI ++++ +v+I +nv+I +g+ i FUN_001957-T1 376 NVTVEDGCKIS-EAILCKNVHIKRNVTISSGSLI 408 6899*******.********************98 PP == domain 4 score: 6.1 bits; conditional E-value: 0.0069 Hexapep 3 vIGdnvkIgpnvvigggvvI 22 I nv++gp+ v+++gv+I FUN_001957-T1 407 LISFNVVVGPDLVLQPGVKI 426 57778999999999999988 PP >> Hexapep_GlmU GlmU-like, C-terminal hexapeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 3.4 7.3e-10 1.4e-06 18 83 .. 336 402 .. 329 406 .. 0.91 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 7.3e-10 Hexapep_GlmU 18 dslvsggcii.sgaeverSvlssnvrvesgaeveesvllpeveigrgarlrraiidknveipeglvi 83 + l+s+g+ + g+ +++Sv+++n+ + + +++ l ++v+++ g+++++ai+ knv+i+ +++i FUN_001957-T1 336 NVLISKGTSVgAGTVITNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTI 402 7799***9983566789*********************************************99988 PP >> LbH_GLGC GLGC left-handed parallel beta-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.6 7.6e-05 0.15 74 100 .. 343 369 .. 333 376 .. 0.87 2 ! 13.2 0.5 4.5e-05 0.088 73 103 .. 376 406 .. 370 432 .. 0.83 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 7.6e-05 LbH_GLGC 74 lgiGentviknaiiDknariGknvkik 100 +++G++tvi+n++i +n+ iG+ v++ FUN_001957-T1 343 TSVGAGTVITNSVIGRNCVIGDSVQLD 369 579*********************986 PP == domain 2 score: 13.2 bits; conditional E-value: 4.5e-05 LbH_GLGC 73 plgiGentviknaiiDknariGknvkiknkd 103 ++++ ++++i++ai+ kn++i +nv+i++ + FUN_001957-T1 376 NVTVEDGCKISEAILCKNVHIKRNVTISSGS 406 578999*********************9765 PP >> DCTN5 Dynactin subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.1 2.1e+02 37 68 .. 99 129 .. 77 136 .. 0.77 2 ? 9.3 2.4 0.00058 1.1 33 121 .. 318 407 .. 315 426 .. 0.69 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.1 DCTN5 37 ngktivmndciirgdlanvrvgrhcvvksrsv 68 + ktiv++dc gd + r+ ++ks v FUN_001957-T1 99 DVKTIVVEDCFSVGDA-LREIDRQSLLKSDFV 129 679***********95.456788888888766 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00058 DCTN5 33 nivlngktivmndciirgdla...nvrvgrhcvvksrsvirppfkkfskgvaffplhigdhvfieedcvvnaaqigsyvhvgkncvigrrcv 121 n+ l+ + + dci+ ++ vg v+ svi + v + +h+ d v +e+ c + a + vh+ +n+ i + FUN_001957-T1 318 NVYLDTELSLARDCILEENVLiskGTSVGAGTVIT-NSVIGRN-CVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTISSGSL 407 66677777777888887765311124466655554.4444333.346778999999999999999999999999999999999999876555 PP >> Hexapep_2 Hexapeptide repeat of succinyl-transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.6 0.32 6.3e+02 25 33 .. 344 352 .. 329 353 .. 0.62 2 ? 13.7 0.7 2.7e-05 0.053 3 30 .. 355 383 .. 354 387 .. 0.90 3 ? -1.1 0.0 1.2 2.3e+03 20 33 .. 390 403 .. 388 409 .. 0.57 4 ? -1.9 0.1 2.1 4.1e+03 18 26 .. 412 420 .. 396 428 .. 0.51 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.32 Hexapep_2 25 vvgAGvvvt 33 vgAG+v+t FUN_001957-T1 344 SVGAGTVIT 352 356666665 PP == domain 2 score: 13.7 bits; conditional E-value: 2.7e-05 Hexapep_2 3 iIGdnCliGansgi.GvslGdncvvgAGv 30 +IG nC+iG ++ Gv+l dn++v+ G+ FUN_001957-T1 355 VIGRNCVIGDSVQLdGVHLWDNVTVEDGC 383 6********999999**********9776 PP == domain 3 score: -1.1 bits; conditional E-value: 1.2 Hexapep_2 20 lGdncvvgAGvvvt 33 l++n+++ +v++ FUN_001957-T1 390 LCKNVHIKRNVTIS 403 55555555555553 PP == domain 4 score: -1.9 bits; conditional E-value: 2.1 Hexapep_2 18 vslGdncvv 26 v +G + v+ FUN_001957-T1 412 VVVGPDLVL 420 445555555 PP >> Fucose_pyrophosphorylase Fucose pyrophosphorylase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.5 0.00012 0.23 287 351 .. 344 405 .. 307 421 .. 0.75 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00012 Fucose_pyrophosphorylase 287 s.eesavvinsilepsvsvgegsvieysslkgevsigsncivsglelsssealklelpddvilqel 351 s ++ v++ns++ ++ +g++ + +l ++v++ +c +s+ l + +++++++v + + FUN_001957-T1 344 SvGAGTVITNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCK----NVHIKRNVTISSG 405 2467889999999999999999999999999999999999999998888....7777777766654 PP >> Ig_NUP210_1st NUP210 Ig-like domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.0013 2.6 3 60 .. 40 103 .. 38 110 .. 0.65 2 ? 1.0 0.0 0.35 6.9e+02 67 89 .. 173 195 .. 150 198 .. 0.86 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0013 Ig_NUP210_1st 3 kLnvprvLLPyss....evsvnftLevteggCykwsssrpdvvsvepieekee..eeeCskkav 60 +L +prvLLP+ + + +++f +e+ + + + s + d v+ + ++k + ++ C k + FUN_001957-T1 40 TLETPRVLLPLVNvpllDYTIEFLVEAGVQEIFVFCSAHADQVKKHISQSKWTgaRSPCDVKTI 103 699*********9333335555555555557899999998888766444432233556655555 PP == domain 2 score: 1.0 bits; conditional E-value: 0.35 Ig_NUP210_1st 67 ekkrqtavvlaedketgevlrcd 89 + ++ +++a +++tg +l+c+ FUN_001957-T1 173 ARCQEEDLIVAMNSRTGRILHCE 195 456778899*************7 PP >> TPR_28 GBF1-like, tetratrico peptide repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00018 0.35 19 96 .. 556 637 .. 546 653 .. 0.77 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00018 TPR_28 19 npcrdirhqaisalqrs.llspelastdhtewiaifgevlfplilrllkpevyqsdpvgmsetr.vqa..atlvckiflhyl 96 + c+++ + + +l s l p l+ dh++ + e l+p+i + +k q d + +e +q+ a+ + ++flh l FUN_001957-T1 556 ETCQELNQAVVKSLLEScLNDPSLSKQDHSKNLKKTTEDLLPVISKYIKTADGQRDALNATEEFfLQTmwAAPLFQVFLHML 637 578888887776665551668************************************9988764133322455567777766 PP >> NTP_transf_3 MobA-like NTP transferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00027 0.52 15 59 .. 44 90 .. 40 136 .. 0.86 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00027 NTP_transf_3 15 dKallplggkpllervlerlrpagvdevvvvand..eevaaalaelg 59 ++ llpl + pll++++e l +agv+e++v + + ++v++++++ + FUN_001957-T1 44 PRVLLPLVNVPLLDYTIEFLVEAGVQEIFVFCSAhaDQVKKHISQSK 90 6789***************************9885567777666654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (706 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1021 (0.0399687); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 6871.57 // Query: FUN_001957-T2 [L=683] Description: FUN_001957 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-38 130.9 4.4 4.8e-38 129.9 4.4 1.6 1 LbH_EIF2B EIF2B subunit epsilon LbH domain 2.8e-13 50.1 9.8 2.6e-11 43.8 5.7 2.6 2 GMPPB_C GMPPB C-terminal domain 3.5e-11 43.5 0.1 1.1e-10 41.9 0.1 1.9 1 W2 eIF4-gamma/eIF5/eIF2-epsilon 4.7e-10 39.9 0.0 7.5e-10 39.3 0.0 1.3 1 NTP_transferase Nucleotidyl transferase 1.5e-09 37.6 12.5 0.002 18.3 1.4 4.5 4 Hexapep Bacterial transferase hexapeptide ( 9.6e-07 29.4 5.4 1.4e-06 28.8 3.5 2.3 1 Hexapep_GlmU GlmU-like, C-terminal hexapeptide 0.00012 22.5 7.6 0.084 13.3 0.5 2.8 3 LbH_GLGC GLGC left-handed parallel beta-heli ------ inclusion threshold ------ 0.028 14.5 5.2 1.1 9.4 2.3 3.3 2 DCTN5 Dynactin subunit 5 0.051 13.8 0.7 0.051 13.8 0.7 3.6 4 Hexapep_2 Hexapeptide repeat of succinyl-tran 0.1 12.0 0.5 0.22 10.9 0.5 1.5 1 Fucose_pyrophosphorylase Fucose pyrophosphorylase domain 0.15 12.8 0.2 2.5 8.8 0.0 2.5 2 Ig_NUP210_1st NUP210 Ig-like domain 1 0.18 12.0 0.0 0.32 11.1 0.0 1.3 1 TPR_28 GBF1-like, tetratrico peptide repea 0.27 11.9 0.0 0.5 11.0 0.0 1.4 1 NTP_transf_3 MobA-like NTP transferase domain Domain annotation for each model (and alignments): >> LbH_EIF2B EIF2B subunit epsilon LbH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.9 4.4 2.5e-41 4.8e-38 1 104 [. 316 419 .. 316 420 .. 0.98 Alignments for each domain: == domain 1 score: 129.9 bits; conditional E-value: 2.5e-41 LbH_EIF2B 1 rgniYkekdvslarsckieenvviGkgtsigentkisnSviGrnckIgknvkiegsyiwdnvtiednckieksiiadgvvikegvkiekgcvlsfg 96 r+n+Y ++++slar+c +eenv+i kgts+g++t+i+nSviGrnc+Ig+ v+++g ++wdnvt+ed+cki+++i++++v+ik++v+i++g+++sf+ FUN_001957-T2 316 RHNVYLDTELSLARDCILEENVLISKGTSVGAGTVITNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTISSGSLISFN 411 89********************************************************************************************** PP LbH_EIF2B 97 vvvgpnvt 104 vvvgp+++ FUN_001957-T2 412 VVVGPDLV 419 *****976 PP >> GMPPB_C GMPPB C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 3e-06 0.0059 3 42 .. 317 356 .. 315 356 .. 0.96 2 ! 43.8 5.7 1.3e-14 2.6e-11 2 93 .. 334 424 .. 333 437 .. 0.90 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 3e-06 GMPPB_C 3 gnvlihpsakigegavigpnvvigknvvigegvriknsii 42 nv+++ + + ++++++ nv i+k++++g+g+ i+ns+i FUN_001957-T2 317 HNVYLDTELSLARDCILEENVLISKGTSVGAGTVITNSVI 356 699***********************************98 PP == domain 2 score: 43.8 bits; conditional E-value: 1.3e-14 GMPPB_C 2 ignvlihpsakigegavigpnvvigknvvigegvriknsiilegvkikdhalvkksIiGwkskigkwarieelsvlGedVevkdevlvngai 93 ++nvli++ +++g+g+vi n vig+n+vig+ v ++ + ++v+++d + ++++I+ ++ +i++ + i++ s+++ +V v +++++ + FUN_001957-T2 334 EENVLISKGTSVGAGTVI-TNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTISSGSLISFNVVVGPDLVLQPGV 424 689***************.7999************************************************************999998544 PP >> W2 eIF4-gamma/eIF5/eIF2-epsilon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.9 0.1 5.8e-14 1.1e-10 2 63 .. 609 674 .. 608 678 .. 0.86 Alignments for each domain: == domain 1 score: 41.9 bits; conditional E-value: 5.8e-14 W2 2 qvdlllaleefcaeseklkklllkilkaLYdlDiveEeailkWwekkssaekg....kkkvrkkak 63 q+d+l+a+eef+ + + +++l++ +l++LYd++++eE +il+W+ + + + + +kk+r++++ FUN_001957-T2 609 QRDALNATEEFFLQTMWAAPLFQVFLHMLYDKEVLEESVILQWYLHRRGDISCfepqRKKLRQQVA 674 89******************************************9977753225555778888875 PP >> NTP_transferase Nucleotidyl transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.0 3.8e-13 7.5e-10 2 129 .. 25 153 .. 24 170 .. 0.86 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 3.8e-13 NTP_transferase 2 aiILaGGsGtRLwPLTrtlakplvpvldkeplidytlsrllnagieeiiviltqekseeveellkdgskfg.....veityalepegkgtAdAv 90 a+IL+ R+ P+T + + l+p ++ pl+dyt++ l++ag++e i++ + ++ +v++++++ + ++ ++++ ++ + dA+ FUN_001957-T2 25 AVILSDSFNFRFLPITLETPRVLLPLVNV-PLLDYTIEFLVEAGVQE-IFVFCSAHADQVKKHISQSK-WTgarspCDVKTIVVEDCFSVGDAL 115 6788888888*******************.*****************.999999***********987.5558888888888888888999999 PP NTP_transferase 91 alaaefledekslvlvLggDhlikddleeavkkakekaa 129 +++ +++ ++ ++gD++ +++le++++++ke+ + FUN_001957-T2 116 REIDRQSLLKSD-FVLVSGDVVSNMKLEQVFQEHKERRN 153 999877777776.999********************987 PP >> Hexapep Bacterial transferase hexapeptide (six repeats) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 1.7 0.00017 0.34 2 27 .. 337 361 .. 330 361 .. 0.67 2 ! 18.3 1.4 1e-06 0.002 1 29 [. 359 386 .. 353 387 .. 0.69 3 ! 14.9 0.8 1.1e-05 0.022 1 34 [. 376 408 .. 376 410 .. 0.95 4 ! 6.2 0.1 0.0067 13 3 22 .. 407 426 .. 405 428 .. 0.78 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00017 Hexapep 2 tvIGdnvkIgpnvvigggvvIGdnvi 27 + I +++ +g+++vi + vIG+n++ FUN_001957-T2 337 VLISKGTSVGAGTVI-TNSVIGRNCV 361 556677777777777.6666777775 PP == domain 2 score: 18.3 bits; conditional E-value: 1e-06 Hexapep 1 gtvIGdnvkIgpnvvigggvvIGdnviIg 29 ++vIGd v+++ +v++ ++v++ d+++I FUN_001957-T2 359 NCVIGDSVQLD-GVHLWDNVTVEDGCKIS 386 45666666666.88888888888888885 PP == domain 3 score: 14.9 bits; conditional E-value: 1.1e-05 Hexapep 1 gtvIGdnvkIgpnvvigggvvIGdnviIgagvvi 34 +++++d++kI ++++ +v+I +nv+I +g+ i FUN_001957-T2 376 NVTVEDGCKIS-EAILCKNVHIKRNVTISSGSLI 408 6899*******.********************98 PP == domain 4 score: 6.2 bits; conditional E-value: 0.0067 Hexapep 3 vIGdnvkIgpnvvigggvvI 22 I nv++gp+ v+++gv+I FUN_001957-T2 407 LISFNVVVGPDLVLQPGVKI 426 57778999999999999988 PP >> Hexapep_GlmU GlmU-like, C-terminal hexapeptide # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.8 3.5 7.2e-10 1.4e-06 18 83 .. 336 402 .. 329 406 .. 0.91 Alignments for each domain: == domain 1 score: 28.8 bits; conditional E-value: 7.2e-10 Hexapep_GlmU 18 dslvsggcii.sgaeverSvlssnvrvesgaeveesvllpeveigrgarlrraiidknveipeglvi 83 + l+s+g+ + g+ +++Sv+++n+ + + +++ l ++v+++ g+++++ai+ knv+i+ +++i FUN_001957-T2 336 NVLISKGTSVgAGTVITNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTI 402 7799***9983566789*********************************************99988 PP >> LbH_GLGC GLGC left-handed parallel beta-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 7.8 1.5e+04 71 97 .. 89 115 .. 78 127 .. 0.65 2 ! 12.5 0.6 7.3e-05 0.14 74 100 .. 343 369 .. 333 376 .. 0.87 3 ! 13.3 0.5 4.3e-05 0.084 73 103 .. 376 406 .. 370 432 .. 0.83 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 7.8 LbH_GLGC 71 kvplgiGentviknaiiDknariGknv 97 + +g + + +k ++ ++G+ FUN_001957-T2 89 SKWTGARSPCDVKTIVVEDCFSVGDAL 115 445566667777777777777777665 PP == domain 2 score: 12.5 bits; conditional E-value: 7.3e-05 LbH_GLGC 74 lgiGentviknaiiDknariGknvkik 100 +++G++tvi+n++i +n+ iG+ v++ FUN_001957-T2 343 TSVGAGTVITNSVIGRNCVIGDSVQLD 369 579*********************986 PP == domain 3 score: 13.3 bits; conditional E-value: 4.3e-05 LbH_GLGC 73 plgiGentviknaiiDknariGknvkiknkd 103 ++++ ++++i++ai+ kn++i +nv+i++ + FUN_001957-T2 376 NVTVEDGCKISEAILCKNVHIKRNVTISSGS 406 578999*********************9765 PP >> DCTN5 Dynactin subunit 5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.1 2e+02 37 68 .. 99 129 .. 77 136 .. 0.77 2 ? 9.4 2.3 0.00054 1.1 33 121 .. 318 407 .. 315 426 .. 0.69 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.1 DCTN5 37 ngktivmndciirgdlanvrvgrhcvvksrsv 68 + ktiv++dc gd + r+ ++ks v FUN_001957-T2 99 DVKTIVVEDCFSVGDA-LREIDRQSLLKSDFV 129 679***********95.456788888888766 PP == domain 2 score: 9.4 bits; conditional E-value: 0.00054 DCTN5 33 nivlngktivmndciirgdla...nvrvgrhcvvksrsvirppfkkfskgvaffplhigdhvfieedcvvnaaqigsyvhvgkncvigrrcv 121 n+ l+ + + dci+ ++ vg v+ svi + v + +h+ d v +e+ c + a + vh+ +n+ i + FUN_001957-T2 318 NVYLDTELSLARDCILEENVLiskGTSVGAGTVIT-NSVIGRN-CVIGDSVQLDGVHLWDNVTVEDGCKISEAILCKNVHIKRNVTISSGSL 407 66677777777888887765311124466655554.4444333.346778999999999999999999999999999999999999876555 PP >> Hexapep_2 Hexapeptide repeat of succinyl-transferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.6 0.32 6.3e+02 25 33 .. 344 352 .. 329 353 .. 0.62 2 ? 13.8 0.7 2.6e-05 0.051 3 30 .. 355 383 .. 354 387 .. 0.90 3 ? -1.1 0.0 1.1 2.2e+03 20 33 .. 390 403 .. 388 409 .. 0.57 4 ? -1.9 0.1 2 4e+03 18 26 .. 412 420 .. 396 428 .. 0.51 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.32 Hexapep_2 25 vvgAGvvvt 33 vgAG+v+t FUN_001957-T2 344 SVGAGTVIT 352 356666665 PP == domain 2 score: 13.8 bits; conditional E-value: 2.6e-05 Hexapep_2 3 iIGdnCliGansgi.GvslGdncvvgAGv 30 +IG nC+iG ++ Gv+l dn++v+ G+ FUN_001957-T2 355 VIGRNCVIGDSVQLdGVHLWDNVTVEDGC 383 6********999999**********9776 PP == domain 3 score: -1.1 bits; conditional E-value: 1.1 Hexapep_2 20 lGdncvvgAGvvvt 33 l++n+++ +v++ FUN_001957-T2 390 LCKNVHIKRNVTIS 403 55555555555553 PP == domain 4 score: -1.9 bits; conditional E-value: 2 Hexapep_2 18 vslGdncvv 26 v +G + v+ FUN_001957-T2 412 VVVGPDLVL 420 445555555 PP >> Fucose_pyrophosphorylase Fucose pyrophosphorylase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.5 0.00011 0.22 287 351 .. 344 405 .. 307 421 .. 0.75 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00011 Fucose_pyrophosphorylase 287 s.eesavvinsilepsvsvgegsvieysslkgevsigsncivsglelsssealklelpddvilqel 351 s ++ v++ns++ ++ +g++ + +l ++v++ +c +s+ l + +++++++v + + FUN_001957-T2 344 SvGAGTVITNSVIGRNCVIGDSVQLDGVHLWDNVTVEDGCKISEAILCK----NVHIKRNVTISSG 405 2467889999999999999999999999999999999999999998888....7777777766654 PP >> Ig_NUP210_1st NUP210 Ig-like domain 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.0013 2.5 3 60 .. 40 103 .. 38 110 .. 0.65 2 ? 1.1 0.0 0.34 6.6e+02 67 89 .. 173 195 .. 149 198 .. 0.86 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0013 Ig_NUP210_1st 3 kLnvprvLLPyss....evsvnftLevteggCykwsssrpdvvsvepieekee..eeeCskkav 60 +L +prvLLP+ + + +++f +e+ + + + s + d v+ + ++k + ++ C k + FUN_001957-T2 40 TLETPRVLLPLVNvpllDYTIEFLVEAGVQEIFVFCSAHADQVKKHISQSKWTgaRSPCDVKTI 103 699*********9333335555555555557899999998888766444432233556655555 PP == domain 2 score: 1.1 bits; conditional E-value: 0.34 Ig_NUP210_1st 67 ekkrqtavvlaedketgevlrcd 89 + ++ +++a +++tg +l+c+ FUN_001957-T2 173 ARCQEEDLIVAMNSRTGRILHCE 195 456778899*************7 PP >> TPR_28 GBF1-like, tetratrico peptide repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00016 0.32 19 96 .. 556 637 .. 546 654 .. 0.77 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00016 TPR_28 19 npcrdirhqaisalqrs.llspelastdhtewiaifgevlfplilrllkpevyqsdpvgmsetr.vqa..atlvckiflhyl 96 + c+++ + + +l s l p l+ dh++ + e l+p+i + +k q d + +e +q+ a+ + ++flh l FUN_001957-T2 556 ETCQELNQAVVKSLLEScLNDPSLSKQDHSKNLKKTTEDLLPVISKYIKTADGQRDALNATEEFfLQTmwAAPLFQVFLHML 637 578888887776665551668************************************9988764133322455567777766 PP >> NTP_transf_3 MobA-like NTP transferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00025 0.5 15 59 .. 44 90 .. 40 136 .. 0.86 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00025 NTP_transf_3 15 dKallplggkpllervlerlrpagvdevvvvand..eevaaalaelg 59 ++ llpl + pll++++e l +agv+e++v + + ++v++++++ + FUN_001957-T2 44 PRVLLPLVNVPLLDYTIEFLVEAGVQEIFVFCSAhaDQVKKHISQSK 90 6789***************************9885567777666654 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (683 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 686 (0.0268546); expected 510.9 (0.02) Passed bias filter: 528 (0.0206694); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.38u 0.43s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 6394.68 // Query: FUN_001961-T1 [L=479] Description: FUN_001961 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (479 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 788 (0.0308475); expected 510.9 (0.02) Passed bias filter: 703 (0.0275201); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 4675.12 // Query: FUN_001962-T1 [L=101] Description: FUN_001962 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 429 (0.0167939); expected 510.9 (0.02) Passed bias filter: 314 (0.012292); expected 510.9 (0.02) Passed Vit filter: 9 (0.000352319); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1037.56 // Query: FUN_001963-T1 [L=765] Description: FUN_001963 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-20 74.3 0.7 1.9e-20 74.3 0.7 2.0 2 CAP Cysteine-rich secretory protein family 3e-08 34.2 0.0 6.8e-08 33.1 0.0 1.6 1 SEA SEA domain Domain annotation for each model (and alignments): >> CAP Cysteine-rich secretory protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 74.3 0.7 1.5e-24 1.9e-20 1 118 [. 30 148 .. 30 149 .. 0.91 2 ? -2.5 0.2 1 1.3e+04 24 48 .. 258 287 .. 257 310 .. 0.66 Alignments for each domain: == domain 1 score: 74.3 bits; conditional E-value: 1.5e-24 CAP 1 ldlhNelRaaaglppLswdaeLaaaAqehaktcaengshnhrsptggnilarvaaagreniaageesaedavkgWydepgtynygaa.......hr 89 l +hN++Ra + +ppL w+ae a++Aq++a+++a+ + +++p++++ + + +g +++ ++ ++av++Wy+e +y+++ + h+ FUN_001963-T1 30 LTAHNAIRALHDVPPLNWSAETAVNAQKWANHLAAI-DQLQHDPSSTDGENLFYMYG----GDPAQACDRAVNNWYQEIRNYDFKSPhlddstnHF 120 679******************************999.66666677777777777777....88********************************* PP CAP 90 tnllwpkstkvGcavakcgdgsyvfvvcn 118 ++l+w+ s+++G++ a++++g++ f+v FUN_001963-T1 121 SQLVWRGSKELGIGTAQSKSGNF-FLVAR 148 *********************98.77765 PP == domain 2 score: -2.5 bits; conditional E-value: 1 CAP 24 aaAqehaktcaeng.....shnhrsptggn 48 a A++ +++ +++ nh+s + ++ FUN_001963-T1 258 AYAKQETQQMETTQtsnpiKLNHPSENATS 287 679999999988776666555555554444 PP >> SEA SEA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.0 5.3e-12 6.8e-08 3 78 .. 420 489 .. 418 499 .. 0.92 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 5.3e-12 SEA 3 ytgsfkitnleytedlenpsSeefkslskkiesllnelfrksslkkqyiksevlrlspekgsvvvdvvlvfrfpst 78 +++ ++++++ y+ d++ p+S +f +l+++++ ++ +lf + + ++++++++++++ gsv+v + l f+++ + FUN_001963-T1 420 FRVAIRFKDMVYSNDMQTPGSLAFEELKRNVTGAIIKLFDD---DDDFQQVQLISVRN--GSVIVTLGLLFSKD-A 489 8889999**********************************...9*************..***********998.4 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (765 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1132 (0.044314); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 7475.61 // Query: FUN_001965-T1 [L=233] Description: FUN_001965 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-12 46.5 2.0 8.8e-12 45.7 2.0 1.4 1 SUEL_Lectin D-galactoside/L-rhamnose binding SUEL lectin dom Domain annotation for each model (and alignments): >> SUEL_Lectin D-galactoside/L-rhamnose binding SUEL lectin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.7 2.0 3.4e-16 8.8e-12 16 80 .] 2 72 .. 1 72 [. 0.89 Alignments for each domain: == domain 1 score: 45.7 bits; conditional E-value: 3.4e-16 SUEL_Lectin 16 yGrtegetC.pgsaaegtnCease..slakvkkaCqgkesCsvevsnevfggdp...CpgvykyLeveykC 80 +Gr+++++C ++s ++ +C+ +e + a+++ C+g++ C+++++n+++ + Cp+vykyL+v+y+C FUN_001965-T1 2 FGRKDKSICvHPSLPSNMECQEQElqVNAQIRGLCEGENDCEISANNDFMAKAGttiCPNVYKYLDVKYRC 72 9********6578888889*99998899********************996654567************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (233 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 996 (0.03899); expected 510.9 (0.02) Passed bias filter: 441 (0.0172637); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2349.10 // Query: FUN_001966-T1 [L=445] Description: FUN_001966 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-13 49.6 4.7 1.9e-12 47.8 4.7 2.0 1 SUEL_Lectin D-galactoside/L-rhamnose binding SUEL lectin dom Domain annotation for each model (and alignments): >> SUEL_Lectin D-galactoside/L-rhamnose binding SUEL lectin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.8 4.7 7.5e-17 1.9e-12 1 80 [] 166 252 .. 166 252 .. 0.88 Alignments for each domain: == domain 1 score: 47.8 bits; conditional E-value: 7.5e-17 SUEL_Lectin 1 lsCp.egkvisvksAsyGrtegetCpgsaaegt.nCease..slakvkkaCqgkesCsvevsnevfggdp...CpgvykyLeveykC 80 ++Cp +++ i+++s++yGr++++tC+++ ++ +C+++e + +k+ + Cqg+++C+v ++++++g+++ Cp+vyky +v y+C FUN_001966-T1 166 IKCPnKYDRIAIYSTFYGRDDNTTCQHKILPSKgRCTQEEqrVNTKLYDLCQGESKCTVAATTSFLGKNNsviCPDVYKYARVIYRC 252 689967899****************7554433336998877799**********************9987899*************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (445 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 988 (0.0386768); expected 510.9 (0.02) Passed bias filter: 385 (0.0150714); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4305.30 // Query: FUN_001968-T1 [L=183] Description: FUN_001968 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (183 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 655 (0.025641); expected 510.9 (0.02) Passed bias filter: 391 (0.0153063); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1846.89 // Query: FUN_001969-T1 [L=285] Description: FUN_001969 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0037 18.0 4.5 0.01 16.5 1.9 2.1 2 ARS2 Arsenite-resistance protein 2 0.004 17.3 0.1 0.0085 16.3 0.1 1.7 1 Zn_SUZ12 Polycomb protein SUZ12-like, Zn domain 0.0082 16.4 1.8 0.02 15.2 1.8 1.6 1 zf-FCS MYM-type Zinc finger with FCS sequence moti ------ inclusion threshold ------ 0.014 16.5 3.4 0.014 16.5 3.4 2.4 3 YcgJ YcgJ protein 0.015 16.4 3.6 0.015 16.4 3.6 2.2 2 zf-C2H2_4 C2H2-type zinc finger 0.43 11.5 5.1 0.69 10.9 0.4 2.3 2 OrsD Orsellinic acid/F9775 biosynthesis cluster 3.5 8.4 10.4 0.16 12.7 4.4 1.9 2 zf-C2H2_2 C2H2 type zinc-finger (2 copies) 3.9 7.7 6.0 0.89 9.8 0.8 2.3 2 zf-C2H2_12 Spin-doc zinc-finger Domain annotation for each model (and alignments): >> ARS2 Arsenite-resistance protein 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 1.9 3.2e-06 0.01 38 123 .. 33 128 .. 14 156 .. 0.76 2 ? 2.1 0.0 0.087 2.8e+02 14 73 .. 179 239 .. 169 262 .. 0.70 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 3.2e-06 ARS2 38 eeilklgkk.dpekevEkfvekntqElakdKwlCplsGKkFkapEFvrKHilnKHadkveevrkeve........fFnnylaDakrPa.tpelkdk 123 +++ + + d+++e E ++e+ +E +++ C K k+ + +Hi KH+d+ ++ +++ + F + + D+k+ ++e dk FUN_001969-T1 33 DDLDAIFEAlDEDEEFEDYLEAVVEEVQNEGVCCEFCSKICKSKQGLSRHIAAKHKDQEQATKTKKKketvfkydVFAQLVKDTKQNIiQCEVFDK 128 555554443166789*****************************************9987776554444665555577777777776656665444 PP == domain 2 score: 2.1 bits; conditional E-value: 0.087 ARS2 14 vvewqkkfeekleellsek..etlseeeilklgkkdpekevEkfvekntqElakdKwlCpls 73 +++ k++ ++ + l+ +k +tl +++ kk +k+v + v+ ++Ela+ ++l + FUN_001969-T1 179 SSKYFKGLSQRAATLFATKlaDTL-LGHAKEGLKKNSAKDVVTTVSLSKNELAGMQYLGGYV 239 567778888888888765433666.3455555688999999999**********99997654 PP >> Zn_SUZ12 Polycomb protein SUZ12-like, Zn domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.1 2.7e-06 0.0085 18 48 .. 58 88 .. 47 117 .. 0.86 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 2.7e-06 Zn_SUZ12 18 tevtedlsCpfCllkcgslkgLlkHLklsHd 48 ++e ++C fC+ c+s +gL H+ + H+ FUN_001969-T1 58 EVQNEGVCCEFCSKICKSKQGLSRHIAAKHK 88 4456889***********************7 PP >> zf-FCS MYM-type Zinc finger with FCS sequence motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 1.8 6.2e-06 0.02 17 38 .. 55 76 .. 51 76 .. 0.92 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 6.2e-06 zf-FCS 17 kpetlswdgsvkqFCSesClds 38 ++e+++++g++ +FCS++C+++ FUN_001969-T1 55 VVEEVQNEGVCCEFCSKICKSK 76 689****************986 PP >> YcgJ YcgJ protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.5 3.4 4.2e-06 0.014 4 48 .. 60 104 .. 58 138 .. 0.84 2 ? -3.0 0.0 5.3 1.7e+04 21 39 .. 161 179 .. 159 198 .. 0.67 3 ? -0.9 0.1 1.1 3.6e+03 41 68 .. 244 275 .. 231 282 .. 0.58 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 4.2e-06 YcgJ 4 pekgvvCDkkakvCadsqGiSlelTkkylgkkaekkllselsgdf 48 ++gv C +k+C +qG+S ++ +k+ ++++++k +++ ++ f FUN_001969-T1 60 QNEGVCCEFCSKICKSKQGLSRHIAAKHKDQEQATKTKKKKETVF 104 679*********************************999855444 PP == domain 2 score: -3.0 bits; conditional E-value: 5.3 YcgJ 21 qGiSlelTkkylgkkaekk 39 +G S ++ +k++g+ a + FUN_001969-T1 161 KGNSEAFYAKFYGEIALNS 179 6778888888888766554 PP == domain 3 score: -0.9 bits; conditional E-value: 1.1 YcgJ 41 lsels....gdfdsteftlsngvfCdvkeklC 68 ++ + +++++++ +s ++C++++k FUN_001969-T1 244 HKKHRtskhKATTENQQAISILTACRLQDKEG 275 44322233366666667777777777777655 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.4 3.6 4.8e-06 0.015 2 24 .] 65 87 .. 64 87 .. 0.96 2 ? -4.0 1.5 8 2.6e+04 17 24 .] 245 252 .. 240 252 .. 0.62 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 4.8e-06 zf-C2H2_4 2 kCpiCgksFsskkaLrrHlkkhH 24 +C++C+k ++sk++L+rH++ H FUN_001969-T1 65 CCEFCSKICKSKQGLSRHIAAKH 87 8******************9998 PP == domain 2 score: -4.0 bits; conditional E-value: 8 zf-C2H2_4 17 rrHlkkhH 24 ++H + H FUN_001969-T1 245 KKHRTSKH 252 55888777 PP >> OrsD Orsellinic acid/F9775 biosynthesis cluster protein D # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.4 0.00022 0.69 12 49 .. 64 103 .. 40 130 .. 0.62 2 ? 2.5 0.5 0.086 2.7e+02 28 52 .. 241 265 .. 237 283 .. 0.71 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00022 OrsD 12 liCreC.kyavqpselerHLrkrhrqlkrek.tqelleav 49 + C+ C k + +++ l+rH+ ++h+ ++++ t++ +e+v FUN_001969-T1 64 VCCEFCsKICKSKQGLSRHIAAKHKDQEQATkTKKKKETV 103 3466662345555777777777777665554133444444 PP == domain 2 score: 2.5 bits; conditional E-value: 0.086 OrsD 28 rHLrkrhrqlkrektqelleavehe 52 + L+k+hr+ k+++t+e ++a++ FUN_001969-T1 241 QSLHKKHRTSKHKATTENQQAISIL 265 5588999999999999999999544 PP >> zf-C2H2_2 C2H2 type zinc-finger (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 4.4 5.1e-05 0.16 37 94 .. 46 107 .. 37 113 .. 0.67 2 ? -3.1 0.2 4.4 1.4e+04 17 28 .. 246 257 .. 240 265 .. 0.47 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 5.1e-05 zf-C2H2_2 37 eglleylrekise....kleClvCekefkslealreHmkdkgHckiayeeeeekkeieefyd 94 e++ +yl+ ++e + +C +C+k ks++ l H++ k+ + + +++++kke yd FUN_001969-T1 46 EEFEDYLEAVVEEvqneGVCCEFCSKICKSKQGLSRHIAAKHKDQEQATKTKKKKETVFKYD 107 5555555555555444588999****************987655555555455555544455 PP == domain 2 score: -3.1 bits; conditional E-value: 4.4 zf-C2H2_2 17 ehmskkhglfip 28 +h ++kh+ ++ FUN_001969-T1 246 KHRTSKHKATTE 257 333333333333 PP >> zf-C2H2_12 Spin-doc zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.8 0.00028 0.89 15 56 .. 60 99 .. 49 105 .. 0.81 2 ? -0.4 0.4 0.43 1.4e+03 36 49 .. 244 257 .. 239 266 .. 0.83 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00028 zf-C2H2_12 15 grnglvCmvCgeslaslklstikrHieqkHpetlslspeeke 56 +++g+ C C++ +s ++ rHi kH++ + ++ +k+ FUN_001969-T1 60 QNEGVCCEFCSKICKS--KQGLSRHIAAKHKDQEQATKTKKK 99 6788888888888775..7899**********9999888775 PP == domain 2 score: -0.4 bits; conditional E-value: 0.43 zf-C2H2_12 36 ikrHieqkHpetls 49 k+H kH+ t++ FUN_001969-T1 244 HKKHRTSKHKATTE 257 58999999999986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (285 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2174 (0.0851047); expected 510.9 (0.02) Passed bias filter: 646 (0.0252887); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2842.04 // Query: FUN_001970-T1 [L=158] Description: FUN_001970 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (158 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1354 (0.0530045); expected 510.9 (0.02) Passed bias filter: 693 (0.0271286); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.45s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1596.21 // Query: FUN_001971-T1 [L=165] Description: FUN_001971 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.074 14.0 0.3 1.3 10.0 0.1 2.3 2 WZC_N Tyrosine-protein kinase Wzc, N-terminal domain Domain annotation for each model (and alignments): >> WZC_N Tyrosine-protein kinase Wzc, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.1 5e-05 1.3 71 108 .. 51 88 .. 46 90 .. 0.83 2 ? 1.6 0.0 0.02 5.2e+02 25 70 .. 110 158 .. 95 163 .. 0.72 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 5e-05 WZC_N 71 geelleGkvGellaetaegvsllVseldArpGteFtlt 108 e ++eG vG l ++++ g++ lVs+++A ++++++ FUN_001971-T1 51 IEDVVEGVVGDLEQKDKMGYQALVSQIEAGLAERYSVQ 88 46689*******8778888**********988888876 PP == domain 2 score: 1.6 bits; conditional E-value: 0.02 WZC_N 25 pllgsgyawggekievsrldvpkeleg.kkftLtalgngr..YeLsdpd 70 pl+ + + + iev +l + +e e +kf t +g+ + Y+++++ FUN_001971-T1 110 PLTRDPQVADEALIEVMSLAISAETERsNKFSFTSKGKSAkmYTVENSA 158 4444344666778999999999998876899999888754458888754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (165 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1110 (0.0434527); expected 510.9 (0.02) Passed bias filter: 634 (0.0248189); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1684.39 // Query: FUN_001973-T1 [L=114] Description: FUN_001973 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0075 16.4 8.0 0.0087 16.2 8.0 1.1 1 SR-25 Nuclear RNA-splicing-associated protein ------ inclusion threshold ------ 0.087 13.7 1.9 0.17 12.8 1.9 1.4 1 PTN_MK_C PTN/MK heparin-binding protein family, C-terminal 0.44 9.6 4.8 0.47 9.6 4.8 1.1 1 Strabismus Strabismus protein Domain annotation for each model (and alignments): >> SR-25 Nuclear RNA-splicing-associated protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 8.0 1e-06 0.0087 60 115 .. 13 68 .. 7 108 .. 0.51 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1e-06 SR-25 60 rrsssssssssssssssssssssssssgrkkrgkkkdkkrkkkkkkkkkkklkkkk 115 r+ss+ s+s+s+s+ ss s ++++ + k+++ kk k+k++kk + FUN_001973-T1 13 RNSSTGESTSTSTSARSSNSDGEEVDDDKATQVKTREDPLKKAVKHKAEKKREETG 68 33344444444444444444445555555555555544443333333333322222 PP >> PTN_MK_C PTN/MK heparin-binding protein family, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 1.9 2e-05 0.17 15 56 .. 40 79 .. 38 86 .. 0.85 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2e-05 PTN_MK_C 15 daatgtktRtgtLkkalsdaeCeetvkvtKpCkkktkaKaka 56 d+at++ktR + Lkka + e++++ t p ++k+ K+k+ FUN_001973-T1 40 DKATQVKTREDPLKKA-VKHKAEKKREETGPNGRKM-EKLKK 79 889*************.9999999999999999888.45554 PP >> Strabismus Strabismus protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 4.8 5.5e-05 0.47 8 66 .. 41 100 .. 12 112 .. 0.74 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 5.5e-05 Strabismus 8 rshksrdtrsrsekqvtvqapgeesrddeevieveelaqDdnWGetttavtG.tseksis 66 ++++ ++ + +k+v+ +a+++ ++++ + + e+l+++d WG++ +v+G t ++ +s FUN_001973-T1 41 KATQVKTREDPLKKAVKHKAEKKREETGPNGRKMEKLKKNDEWGDSGGVVAGsTRNDDES 100 332333322334557777777777888999999*******************77665555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (114 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1577 (0.0617342); expected 510.9 (0.02) Passed bias filter: 658 (0.0257585); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1149.44 // Query: FUN_001974-T1 [L=81] Description: FUN_001974 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0016 19.3 0.7 0.0021 19.0 0.7 1.3 1 Snapin_Pallidin Snapin/Pallidin 0.0074 16.9 1.9 0.0082 16.8 1.9 1.1 1 ANG-1 ANG-1-like domain ------ inclusion threshold ------ 0.011 16.5 0.2 0.011 16.5 0.2 1.4 2 YwqH-like YwqH-like 0.048 14.0 2.0 0.051 13.9 1.8 1.3 1 TRIM_CC TRIM protein coiled-coil region Domain annotation for each model (and alignments): >> Snapin_Pallidin Snapin/Pallidin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.7 3.2e-07 0.0021 16 51 .. 20 55 .. 9 65 .. 0.87 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 3.2e-07 Snapin_Pallidin 16 keldeklkelrqsQeeLleqidrlaeeLqeleelqe 51 keld+kl elr+sQ+ L++ id+ ++ Lq+l + + FUN_001974-T1 20 KELDSKLPELRRSQDSLRKAIDTRQKLLQTLDANRS 55 699*********************999998877665 PP >> ANG-1 ANG-1-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 1.9 1.3e-06 0.0082 35 84 .. 13 62 .. 3 75 .. 0.88 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.3e-06 ANG-1 35 krvlaletkqqeeLeslreekeqLqellsrqselieeLeksLeaassnss 84 ++v+++e++ +++L +lr+ +++L++ ++++++l+++L+ + +s n s FUN_001974-T1 13 TKVEEIEKELDSKLPELRRSQDSLRKAIDTRQKLLQTLDANRSDTSLNIS 62 79************************************999888887744 PP >> YwqH-like YwqH-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.5 0.2 1.7e-06 0.011 76 120 .. 7 51 .. 2 52 .. 0.92 2 ? -3.3 0.0 2.3 1.5e+04 53 60 .. 65 72 .. 57 76 .. 0.65 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 1.7e-06 YwqH-like 76 syrtvqdkleelisaieqeIerLeseisslqtlldskqsqlqslk 120 + r++ +k+ee+ ++++ + +L+ + sl + +d+ q++lq+l FUN_001974-T1 7 ERRASLTKVEEIEKELDSKLPELRRSQDSLRKAIDTRQKLLQTLD 51 5678899***********************************985 PP == domain 2 score: -3.3 bits; conditional E-value: 2.3 YwqH-like 53 lsseaWnG 60 l++e+Wn FUN_001974-T1 65 LEEENWNA 72 45566664 PP >> TRIM_CC TRIM protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 1.8 8e-06 0.051 53 90 .. 6 43 .. 1 66 [. 0.86 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 8e-06 TRIM_CC 53 eeekaalsqaeglleeLeqeiaeLkkrdaeleqLsqte 90 +e++a l ++e++ +eL ++ eL++ ++ l++ +t FUN_001974-T1 6 SERRASLTKVEEIEKELDSKLPELRRSQDSLRKAIDTR 43 799****************************9977774 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (81 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1769 (0.0692503); expected 510.9 (0.02) Passed bias filter: 1046 (0.0409473); expected 510.9 (0.02) Passed Vit filter: 106 (0.00414954); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 836.82 // Query: FUN_001975-T1 [L=105] Description: FUN_001975 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.27 11.3 0.1 0.3 11.1 0.1 1.1 1 CMV_UL34 Cytomegalovirus transcriptional regulator UL34 Domain annotation for each model (and alignments): >> CMV_UL34 Cytomegalovirus transcriptional regulator UL34 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 1.2e-05 0.3 60 102 .. 22 63 .. 8 75 .. 0.78 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 1.2e-05 CMV_UL34 60 qlkrteeevdlseiekvvksvkCRlrkkeseesetadqellet 102 ++k+++ + ++++++ +++++C++ k e+ +++t ++ + t FUN_001975-T1 22 SMKQESFARNFDKVDGEIHDINCKIEKMEQVPEQTGEDCI-VT 63 577777777********************98877777643.33 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (105 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 529 (0.0207086); expected 510.9 (0.02) Passed bias filter: 484 (0.018947); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.38 # Mc/sec: 1107.26 // Query: FUN_001976-T1 [L=273] Description: FUN_001976 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (273 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1295 (0.0506949); expected 510.9 (0.02) Passed bias filter: 670 (0.0262282); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2732.24 // Query: FUN_001977-T1 [L=251] Description: FUN_001977 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.029 14.9 0.1 0.053 14.1 0.1 1.4 1 ANIS5_cation-bd SXP/RAL-2 family protein Ani s 5-like, metal 0.044 13.2 0.1 0.049 13.0 0.1 1.1 1 CALCOCO1 Calcium binding and coiled-coil domain (CALC 0.057 14.0 0.1 0.22 12.1 0.0 2.0 2 CENP-Q CENP-Q, a CENPA-CAD centromere complex subun 0.062 12.9 0.1 0.085 12.4 0.1 1.3 1 ATG14 Vacuolar sorting 38 and autophagy-related su 0.077 13.6 0.1 0.17 12.5 0.1 1.6 1 bZIP_1 bZIP transcription factor 0.22 11.7 0.1 0.33 11.1 0.1 1.3 1 Endotoxin_N delta endotoxin, N-terminal domain Domain annotation for each model (and alignments): >> ANIS5_cation-bd SXP/RAL-2 family protein Ani s 5-like, metal-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.1 1.2e-05 0.053 6 76 .. 83 154 .. 80 161 .. 0.81 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1.2e-05 ANIS5_cation-bd 6 ffaIl.knetltiaeieeqleawaekygvtdeykefqakvtaqkeevkknvtavisnLssvlekleaIldnk 76 f ++l +++ l +e++ + + + ++v++e++ f+a t+q e +k++v++ ++L++v++ +++ +n FUN_001977-T1 83 FRSLLeSEDGLEFEELNLRPAWEMPNHNVSNEWQSFTAHFTQQFELLKAEVDDLRAELKAVKKTVRELKANP 154 555663344477777776666667889************************************999988776 PP >> CALCOCO1 Calcium binding and coiled-coil domain (CALCOCO1) like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 1.1e-05 0.049 50 188 .. 104 239 .. 89 251 .] 0.77 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.1e-05 CALCOCO1 50 qeaanrqrekekeeykrdreelererkeLesrveelkeelkelrekveelekkqkelealseelaeekdalleqkeesearirELEeDiktltqka 145 e n+++ +e +++ ++ ++ + L+ +v++l++elk +++ v+el+++ k+++a + + + +d ++ ++ ++ + LE l q FUN_001977-T1 104 WEMPNHNVSNE---WQSFTAHFTQQFELLKAEVDDLRAELKAVKKTVRELKANPKNASAPAAGTMATEDPESKFLAAIQNTTKPLEGLKVLLYQLF 196 45555555555...888889999**********************************998877777777777777788888888887777777777 PP CALCOCO1 146 lekEteLeRlkervkkalaqrkeeeaerkqlqakleqteeElr 188 E+ l+ r a +k +er ++++ + t++ lr FUN_001977-T1 197 TADEVCQSSLRGRTTVAGVILKKYGTERAAVDNFIRGTQRKLR 239 7777777777777777777777777777777777766666555 PP >> CENP-Q CENP-Q, a CENPA-CAD centromere complex subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 5.2e-05 0.22 43 76 .. 124 157 .. 111 170 .. 0.91 2 ? -2.0 0.0 1.1 4.9e+03 135 152 .. 173 190 .. 172 195 .. 0.81 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 5.2e-05 CENP-Q 43 hslelLeeeiekeeallesdeeyleeLeknakae 76 ++ elL++e++ + a+l+ +++ +eL++n k++ FUN_001977-T1 124 QQFELLKAEVDDLRAELKAVKKTVRELKANPKNA 157 689**************************98876 PP == domain 2 score: -2.0 bits; conditional E-value: 1.1 CENP-Q 135 khLesmqgnlaqleglne 152 k L +q+++++legl+ FUN_001977-T1 173 KFLAAIQNTTKPLEGLKV 190 568899999999999975 PP >> ATG14 Vacuolar sorting 38 and autophagy-related subunit 14 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 2e-05 0.085 57 141 .. 105 188 .. 76 248 .. 0.75 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 2e-05 ATG14 57 idtkklkleelksevaeseerlkeikdkldqlkkeieekkkkiaklrsslkkrrsdlesasnqleer.rasqleklqdsikrieek 141 ++++++ +e +s +a ++ + +k+ +d l++e+++ kk++++l+++ +++++ +a +++ e + + l+ +q+++k++e FUN_001977-T1 105 EMPNHNVSNEWQSFTAHFTQQFELLKAEVDDLRAELKAVKKTVRELKANP--KNASAPAAGTMATEDpESKFLAAIQNTTKPLEGL 188 566777778889999999*******************************6..5888888888776651566688899999977654 PP >> bZIP_1 bZIP transcription factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 4e-05 0.17 32 62 .. 123 153 .. 116 155 .. 0.90 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 4e-05 bZIP_1 32 errvkaLekeNksLkseleelkkevekLksk 62 +++++ L++e +L+ el+ kk+v +Lk + FUN_001977-T1 123 TQQFELLKAEVDDLRAELKAVKKTVRELKAN 153 7899************************975 PP >> Endotoxin_N delta endotoxin, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 7.8e-05 0.33 60 90 .. 128 158 .. 117 196 .. 0.91 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 7.8e-05 Endotoxin_N 60 klkallkglslslkdfrkevknlkadPknaa 90 lka + l ++lk +k+v++lka+Pkna+ FUN_001977-T1 128 LLKAEVDDLRAELKAVKKTVRELKANPKNAS 158 58999************************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (251 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1494 (0.058485); expected 510.9 (0.02) Passed bias filter: 1092 (0.0427481); expected 510.9 (0.02) Passed Vit filter: 158 (0.00618516); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.36u 0.40s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 2443.16 // Query: FUN_001978-T1 [L=54] Description: FUN_001978 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (54 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 311 (0.0121746); expected 510.9 (0.02) Passed bias filter: 180 (0.00704639); expected 510.9 (0.02) Passed Vit filter: 6 (0.00023488); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.35s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 554.40 // Query: FUN_001979-T1 [L=85] Description: FUN_001979 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.17 12.3 0.0 0.21 12.0 0.0 1.1 1 PH_S11IP STK11-interacting protein PH domain Domain annotation for each model (and alignments): >> PH_S11IP STK11-interacting protein PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 8.3e-06 0.21 40 86 .. 34 80 .. 29 84 .. 0.90 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 8.3e-06 PH_S11IP 40 dlqagrvlerleLdsLekvetseatwteeeeeeelpvleLrFdYisk 86 + ++g+++ ++++ L +ve++ea+++++++ e++ v+ L+F+ + + FUN_001979-T1 34 EKRTGQIVWPVDISYLLNVEATEAMVSSSSKTENADVVCLSFEQVDS 80 5568999999********************************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (85 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 358 (0.0140145); expected 510.9 (0.02) Passed bias filter: 285 (0.0111568); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.23u 0.35s 00:00:00.57 Elapsed: 00:00:00.38 # Mc/sec: 892.57 // Query: FUN_001980-T1 [L=201] Description: FUN_001980 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.051 14.4 0.1 0.12 13.1 0.1 1.7 1 FN3_IL27B_N IL27B N-terminal FN3 domain 0.097 13.3 0.1 1.2 9.7 0.0 2.2 2 Herpes_UL49_2 Herpesvirus UL49 tegument protein Domain annotation for each model (and alignments): >> FN3_IL27B_N IL27B N-terminal FN3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.1 9.6e-06 0.12 8 48 .. 74 114 .. 70 140 .. 0.86 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 9.6e-06 FN3_IL27B_N 8 ssYPqavdCsWtlppapestldtsfvatyrlgvaakeeskp 48 ++ Pq v+ s+tl pa e++ dt++v +++ +++++s + FUN_001980-T1 74 PKVPQEVNSSYTLRPAGEPAIDTAHVEAFKKDLTNSKSSFR 114 567***************************99888777655 PP >> Herpes_UL49_2 Herpesvirus UL49 tegument protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.048 6.1e+02 9 31 .. 13 35 .. 6 48 .. 0.82 2 ? 9.7 0.0 9.6e-05 1.2 47 78 .. 167 198 .. 136 201 .] 0.75 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.048 Herpes_UL49_2 9 alslakklafstaPasasssWrs 31 ++s+a++l s +P++ ++W FUN_001980-T1 13 KMSSARELPQSLSPTEIRQQWGI 35 6899************9999965 PP == domain 2 score: 9.7 bits; conditional E-value: 9.6e-05 Herpes_UL49_2 47 rvaaaqaekaaealWekskPRtnedLdkllet 78 v ++++k Wek+ R n+ L+kl e+ FUN_001980-T1 167 AVTGLHGKKEFSETWEKQASRANQKLNKLSER 198 3456899999******************9775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 960 (0.0375807); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.42 # Mc/sec: 1937.14 // Query: FUN_001981-T1 [L=137] Description: FUN_001981 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (137 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1389 (0.0543746); expected 510.9 (0.02) Passed bias filter: 644 (0.0252104); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1405.39 // Query: FUN_001983-T1 [L=211] Description: FUN_001983 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-06 26.2 0.1 1.4e-05 25.4 0.1 1.4 1 DUF4218 Domain of unknown function (DUF4218) ------ inclusion threshold ------ 0.092 13.4 0.0 0.14 12.8 0.0 1.3 1 DUF4198 Domain of unknown function (DUF4198) 0.18 12.5 0.1 0.7 10.6 0.0 2.0 2 PurS Phosphoribosylformylglycinamidine (FGAM) synthase Domain annotation for each model (and alignments): >> DUF4218 Domain of unknown function (DUF4218) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.1 1.6e-09 1.4e-05 39 90 .. 2 54 .. 1 72 [. 0.89 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 1.6e-09 DUF4218 39 hLivhLateaklaGPvhyrnmypverkllrlksyvrnkarpeGciaeay.lae 90 h++ h+a+ GPvh +my +er + v n+ +pe + e+y +++ FUN_001983-T1 2 HMVRHIARGIASHGPVHSWWMYVYERLNSWICRRVTNRRHPEANVMETYrIFD 54 89999**999999**********************************983444 PP >> DUF4198 Domain of unknown function (DUF4198) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 1.6e-05 0.14 109 168 .. 93 155 .. 42 171 .. 0.68 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.6e-05 DUF4198 109 a........ktlvtvggpsegwdkpvGlplEivPltnpydlkaGeefrfqvl.fdGkPlagaeveveya 168 + t vt g ++ +G + iv+++n +d+k G +++f++ +d k ++ a v+v+ FUN_001983-T1 93 IndpitgktLTWVTTG------KENTGTLTVIVAVQNVSDVKFGKVLKFTFQkVDNKLVESACVHVFSH 155 2344444222333333......447799999********************989***********9875 PP >> PurS Phosphoribosylformylglycinamidine (FGAM) synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 0.5 4.3e+03 49 69 .. 77 97 .. 63 100 .. 0.74 2 ? 10.6 0.0 8.2e-05 0.7 29 61 .. 121 149 .. 108 157 .. 0.80 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.5 PurS 49 deeeaeeeveemceklLaNpv 69 ++e e+e +e c++ + +p+ FUN_001983-T1 77 KAEPQEQEFQESCHRRINDPI 97 455667888899988777665 PP == domain 2 score: 10.6 bits; conditional E-value: 8.2e-05 PurS 29 yeevedVrvgkyieleleaedeeeaeeeveemc 61 +++v+dV+ gk++++++++ d++ ve +c FUN_001983-T1 121 VQNVSDVKFGKVLKFTFQKVDNKL----VESAC 149 789***************988654....44444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (211 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1113 (0.0435702); expected 510.9 (0.02) Passed bias filter: 742 (0.0290468); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2080.94 // Query: FUN_001984-T1 [L=155] Description: FUN_001984 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.093 12.0 0.0 0.12 11.6 0.0 1.1 1 Cas_TM1802 CRISPR-associated protein TM1802 (cas_TM1802 0.094 12.7 0.1 0.13 12.2 0.1 1.1 1 DUF1454 Protein of unknown function (DUF1454) 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 DUF5673 Domain of unknown function (DUF5673) 0.24 12.6 0.6 0.24 12.6 0.6 1.7 2 Ribosomal_S30AE Sigma 54 modulation protein / S30EA ribosoma Domain annotation for each model (and alignments): >> Cas_TM1802 CRISPR-associated protein TM1802 (cas_TM1802) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 1.9e-05 0.12 340 396 .. 35 91 .. 28 101 .. 0.75 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.9e-05 Cas_TM1802 340 ksqsafrIlllIeDVppsrLkkileakdkideefnkllkkekaelkftlgklykff.p 396 k +s +++l l eDV+p +++++ ++ +k+ + + ++++ a++k t +kl kf+ + FUN_001984-T1 35 KGKSIYKVLDLAEDVAPEKISRVKDKVKKSMNPMGHSFD-ALAKYKATTDKLDKFLiY 91 78899************9999995555555555533343.678899999999999932 PP >> DUF1454 Protein of unknown function (DUF1454) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 2e-05 0.13 68 151 .. 6 92 .. 3 100 .. 0.82 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 2e-05 DUF1454 68 kdikasltraaskineklYastaLergtekikslqltl.LPadgaeqkaa..ralaldYmaalirtfePtlskeqskkklselLaag 151 +d++as +aa k+ ++ Yas+ + + ek ks+ l L +d a +k + + ++++ m+ + f + + +++kl++ L+ + FUN_001984-T1 6 QDDAASKFKAAKKLGPRAYASSQIIQAVEKGKSIYKVLdLAEDVAPEKISrvKDKVKKSMNPMGHSFDALAKYKATTDKLDKFLIYK 92 68899999*************************964443778888888773456788999999999998888888899999988754 PP >> DUF5673 Domain of unknown function (DUF5673) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 5.1e-05 0.33 13 43 .. 66 96 .. 63 109 .. 0.92 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 5.1e-05 DUF5673 13 nsylttWddIesYsldeeknklvliyktnkk 43 n++ + +d + +Y+ +++k + liyk++++ FUN_001984-T1 66 NPMGHSFDALAKYKATTDKLDKFLIYKAQNG 96 999*************************997 PP >> Ribosomal_S30AE Sigma 54 modulation protein / S30EA ribosomal protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.6 3.8e-05 0.24 50 86 .] 26 62 .. 4 62 .. 0.90 2 ? -2.9 0.0 2.6 1.7e+04 22 28 .. 82 88 .. 73 94 .. 0.60 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 3.8e-05 Ribosomal_S30AE 50 pgvvlraeeeaedlyaaidlavdklerqlrkykeklk 86 + ++++a e+ +++y+ +dla d + +++ + k+k+k FUN_001984-T1 26 SSQIIQAVEKGKSIYKVLDLAEDVAPEKISRVKDKVK 62 5678999999*************************86 PP == domain 2 score: -2.9 bits; conditional E-value: 2.6 Ribosomal_S30AE 22 lekleky 28 +kl+k+ FUN_001984-T1 82 TDKLDKF 88 3555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (155 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 898 (0.0351537); expected 510.9 (0.02) Passed bias filter: 733 (0.0286945); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1565.72 // Query: FUN_001985-T1 [L=303] Description: FUN_001985 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.046 13.9 0.6 0.12 12.6 0.2 1.8 2 MMADHC Methylmalonic aciduria and homocystinuria type D p 0.13 12.4 1.2 14 5.8 0.2 2.5 2 zf-CCHC_4 Zinc knuckle Domain annotation for each model (and alignments): >> MMADHC Methylmalonic aciduria and homocystinuria type D protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.19 2.4e+03 31 67 .. 57 94 .. 29 127 .. 0.59 2 ? 12.6 0.2 9.3e-06 0.12 21 111 .. 183 286 .. 164 298 .. 0.73 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.19 MMADHC 31 rtvwPdeamgpfgpqdqrf.qLpgnvgfdchlegtaeq 67 ++ +Pd++ g++ + d+ +L + ++ +leg ++q FUN_001985-T1 57 TALKPDNQEGSLRKSDSIAkKLREESKISFKLEGNKKQ 94 45667777777744443211233333333334444333 PP == domain 2 score: 12.6 bits; conditional E-value: 9.3e-06 MMADHC 21 iaispadlgkrtvwPdeamgpf...............gpqdqrfqLpgnvgfdchlegtaeqkkssvhktvpdvLsapssserhelilaqvvnelq 101 + ++++++ + +P+ ++ +f p ++ pg++ f+c +g ++ + + +h++ p+vL++++ + ++l l ++v +l+ FUN_001985-T1 183 RQQQKVKSSVKQSQPSATTTLFagqpqfnfrsssrsfTPTGK--AKPGDICFACSQQGHSRSHYRVTHNSGPQVLASQILVSPQTLELPEYVVDLT 276 444455555555566666666655555555555555566666..66*******************************************9999988 PP MMADHC 102 nkekepakqk 111 +++e+ +++ FUN_001985-T1 277 ITSDEKGSDE 286 7766655554 PP >> zf-CCHC_4 Zinc knuckle # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.0023 30 7 28 .. 68 89 .. 66 103 .. 0.86 2 ? 5.8 0.2 0.0011 14 33 47 .. 230 244 .. 227 246 .. 0.88 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.0023 zf-CCHC_4 7 LrffrrikfesgewalieFkYE 28 Lr++ i+++ +e+++i Fk E FUN_001985-T1 68 LRKSDSIAKKLREESKISFKLE 89 899999*************987 PP == domain 2 score: 5.8 bits; conditional E-value: 0.0011 zf-CCHC_4 33 fCfiCgrlgHsdkfC 47 +Cf C gHs+++ FUN_001985-T1 230 ICFACSQQGHSRSHY 244 8**********9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (303 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1674 (0.0655314); expected 510.9 (0.02) Passed bias filter: 774 (0.0302995); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3007.97 // Query: FUN_001987-T1 [L=179] Description: FUN_001987 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 577 (0.0225876); expected 510.9 (0.02) Passed bias filter: 443 (0.0173419); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1757.53 // Query: FUN_001988-T1 [L=126] Description: FUN_001988 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.003 17.1 1.0 0.0037 16.8 1.0 1.1 1 Stn1 Telomere regulation protein Stn1 Domain annotation for each model (and alignments): >> Stn1 Telomere regulation protein Stn1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 1.0 1.4e-07 0.0037 163 241 .. 44 123 .. 39 126 .] 0.84 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.4e-07 Stn1 163 keLakpweldpeklnelyegedeveeee..stPkkenniqnkadsieqLlkiksve.dklevaspytareesiyvkdeelll 241 k L + e+ +e l+e +e+e +++++ ++P+k+ + ++++eqL +++ + ++ ++ +++++ + + +e++++ FUN_001988-T1 44 KLLDAMVEMLNELLEERQEKETCLKQQRisKHPTKSTK--EASSQCEQLETVNCKNtSDVAIQTDFPVEAHVMEDLKEQVKT 123 678888999999999999999999888899******99..99*******986544314688999******999998888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (126 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2333 (0.091329); expected 510.9 (0.02) Passed bias filter: 914 (0.03578); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1248.51 // Query: FUN_001989-T1 [L=374] Description: FUN_001989 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-08 33.7 0.1 1.1e-07 32.5 0.1 1.7 1 BEN BEN domain ------ inclusion threshold ------ 0.013 16.1 0.2 7.3 7.2 0.0 2.6 2 DUF2540 Protein of unknown function (DUF2540) 0.039 15.0 0.1 0.13 13.4 0.1 1.8 1 PPARgamma_N PPAR gamma N-terminal region 0.13 12.5 1.6 0.16 12.2 0.2 1.8 2 Hormone_1 Somatotropin hormone family 1.2 10.1 4.4 8.8 7.2 0.7 2.8 2 Csm1_N Csm1 N-terminal domain Domain annotation for each model (and alignments): >> BEN BEN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 0.1 2.1e-11 1.1e-07 3 74 .. 292 360 .. 290 362 .. 0.96 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 2.1e-11 BEN 3 arkLlvalFpeevlathsvtGkrsrafksnkpgLDplkvqlIrnyveerfps...kedevwwkecveqvnktirr 74 a kLl ++F++e la ++ G k++LD++k++ +r +v +fp k+ e +wk + ++n+ +r+ FUN_001989-T1 292 ALKLLPHFFSKEELAESNTDGS------YDKQCLDSTKLNSLRVLVFSKFPLganKDKEKVWKFVKGKINSKCRT 360 679*******************......77*******************************************98 PP >> DUF2540 Protein of unknown function (DUF2540) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.2 0.0037 19 19 46 .. 136 163 .. 131 187 .. 0.81 2 ? 7.2 0.0 0.0014 7.3 12 43 .. 219 250 .. 216 261 .. 0.86 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0037 DUF2540 19 klenlenvdvetlkkakeaekktkktlt 46 +len+e+v ++l++ e + ++ k+l+ FUN_001989-T1 136 RLENIEAVTTQILGNQMEMKDHFVKLLE 163 69*******************9999984 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0014 DUF2540 12 elRYllHklenlenvdvetlkkakeaekktkk 43 ++R lH +++l +d tl e ++ t + FUN_001989-T1 219 KVREPLHDIQDLSTIDFTTLDDLHEDNQATPR 250 78999****************99999987766 PP >> PPARgamma_N PPAR gamma N-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.1 2.5e-05 0.13 31 65 .. 226 260 .. 216 277 .. 0.87 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 2.5e-05 PPARgamma_N 31 DiKplttvDysSiSsmayedsplseedltsidyky 65 Di+ l+t+D++ + +++ ++ + ++ +++s++ + FUN_001989-T1 226 DIQDLSTIDFTTLDDLHEDNQATPRVHQASASQEV 260 9***************************9998754 PP >> Hormone_1 Somatotropin hormone family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.2 3.2e-05 0.16 106 156 .. 127 177 .. 98 189 .. 0.83 2 ? -2.2 0.1 0.78 4e+03 9 64 .. 291 348 .. 287 364 .. 0.64 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 3.2e-05 Hormone_1 106 kePLkhlvtelssmkevsetilskakeieeklkeLlegierilskvevpve 156 +e ++l+ l+++++v+ +il +e++++ +Lle +++ +sk+e FUN_001989-T1 127 TEECHDLRLRLENIEAVTTQILGNQMEMKDHFVKLLEKLQASVSKIEHRIS 177 566789999*************************************96433 PP == domain 2 score: -2.2 bits; conditional E-value: 0.78 Hormone_1 9 wenvasapsvavddesclksledlFdnAtslshnlsnlaaelfteFeekyaqkkq...l 64 + ++ p +++e ++++ +d+ + s++l+ l + +f++F + k+ FUN_001989-T1 291 CA-LKLLPHFFSKEELAESNTDGSYDKQCLDSTKLNSLRVLVFSKFPLGANKDKEkvwK 348 55.56666666666777777778888888888888888888888886655555554442 PP >> Csm1_N Csm1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.7 0.0017 8.8 31 59 .. 118 146 .. 116 157 .. 0.87 2 ? 3.7 0.4 0.022 1.1e+02 32 65 .. 148 184 .. 142 187 .. 0.73 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0017 Csm1_N 31 vLsqkletkdqeiesLkeqlaeleekvke 59 +L+q+l ++++e + L+ +l+++e+ + FUN_001989-T1 118 LLRQQLAKRTEECHDLRLRLENIEAVTTQ 146 699*******************9987665 PP == domain 2 score: 3.7 bits; conditional E-value: 0.022 Csm1_N 32 Lsqkletkdq...eiesLkeqlaeleekvkeleerrk 65 L +++e kd+ +e+L++ + ++e++++e++++ + FUN_001989-T1 148 LGNQMEMKDHfvkLLEKLQASVSKIEHRISESDTKVN 184 55666666651114579999**********9998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (374 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1356 (0.0530828); expected 510.9 (0.02) Passed bias filter: 659 (0.0257976); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3652.10 // Query: FUN_001989-T2 [L=388] Description: FUN_001989 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-08 34.0 0.1 1.1e-07 32.4 0.1 1.9 1 BEN BEN domain ------ inclusion threshold ------ 0.013 16.0 0.2 7.7 7.2 0.0 2.7 2 DUF2540 Protein of unknown function (DUF2540) 0.042 14.9 0.1 0.13 13.3 0.1 1.8 1 PPARgamma_N PPAR gamma N-terminal region 0.13 12.5 1.5 0.17 12.1 0.2 1.8 2 Hormone_1 Somatotropin hormone family 1.1 10.2 4.4 9.3 7.2 0.7 3.0 2 Csm1_N Csm1 N-terminal domain Domain annotation for each model (and alignments): >> BEN BEN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 0.1 2.2e-11 1.1e-07 3 74 .. 306 374 .. 304 376 .. 0.96 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 2.2e-11 BEN 3 arkLlvalFpeevlathsvtGkrsrafksnkpgLDplkvqlIrnyveerfps...kedevwwkecveqvnktirr 74 a kLl ++F++e la ++ G k++LD++k++ +r +v +fp k+ e +wk + ++n+ +r+ FUN_001989-T2 306 ALKLLPHFFSKEELAESNTDGS------YDKQCLDSTKLNSLRVLVFSKFPLganKDKEKVWKFVKGKINSKCRT 374 679*******************......77*******************************************98 PP >> DUF2540 Protein of unknown function (DUF2540) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.2 0.0038 20 19 46 .. 150 177 .. 145 201 .. 0.81 2 ? 7.2 0.0 0.0015 7.7 12 43 .. 233 264 .. 230 275 .. 0.86 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0038 DUF2540 19 klenlenvdvetlkkakeaekktkktlt 46 +len+e+v ++l++ e + ++ k+l+ FUN_001989-T2 150 RLENIEAVTTQILGNQMEMKDHFVKLLE 177 69*******************9999984 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0015 DUF2540 12 elRYllHklenlenvdvetlkkakeaekktkk 43 ++R lH +++l +d tl e ++ t + FUN_001989-T2 233 KVREPLHDIQDLSTIDFTTLDDLHEDNQATPR 264 78999****************99999987766 PP >> PPARgamma_N PPAR gamma N-terminal region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 2.6e-05 0.13 31 65 .. 240 274 .. 230 291 .. 0.87 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.6e-05 PPARgamma_N 31 DiKplttvDysSiSsmayedsplseedltsidyky 65 Di+ l+t+D++ + +++ ++ + ++ +++s++ + FUN_001989-T2 240 DIQDLSTIDFTTLDDLHEDNQATPRVHQASASQEV 274 9***************************9998754 PP >> Hormone_1 Somatotropin hormone family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.2 3.4e-05 0.17 106 156 .. 141 191 .. 112 203 .. 0.83 2 ? -2.3 0.1 0.85 4.3e+03 9 64 .. 305 362 .. 302 378 .. 0.63 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 3.4e-05 Hormone_1 106 kePLkhlvtelssmkevsetilskakeieeklkeLlegierilskvevpve 156 +e ++l+ l+++++v+ +il +e++++ +Lle +++ +sk+e FUN_001989-T2 141 TEECHDLRLRLENIEAVTTQILGNQMEMKDHFVKLLEKLQASVSKIEHRIS 191 566789999*************************************96433 PP == domain 2 score: -2.3 bits; conditional E-value: 0.85 Hormone_1 9 wenvasapsvavddesclksledlFdnAtslshnlsnlaaelfteFeekyaqkkq...l 64 + ++ p +++e ++++ +d+ + s++l+ l + +f++F + k+ FUN_001989-T2 305 CA-LKLLPHFFSKEELAESNTDGSYDKQCLDSTKLNSLRVLVFSKFPLGANKDKEkvwK 362 55.56666666666677777778888888888888888888888886655555554442 PP >> Csm1_N Csm1 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.7 0.0018 9.3 31 59 .. 132 160 .. 130 171 .. 0.87 2 ? 3.6 0.4 0.023 1.2e+02 32 65 .. 162 198 .. 156 201 .. 0.73 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0018 Csm1_N 31 vLsqkletkdqeiesLkeqlaeleekvke 59 +L+q+l ++++e + L+ +l+++e+ + FUN_001989-T2 132 LLRQQLAKRTEECHDLRLRLENIEAVTTQ 160 699*******************9987665 PP == domain 2 score: 3.6 bits; conditional E-value: 0.023 Csm1_N 32 Lsqkletkdq...eiesLkeqlaeleekvkeleerrk 65 L +++e kd+ +e+L++ + ++e++++e++++ + FUN_001989-T2 162 LGNQMEMKDHfvkLLEKLQASVSKIEHRISESDTKVN 198 55666666651114579999**********9998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (388 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1521 (0.059542); expected 510.9 (0.02) Passed bias filter: 696 (0.027246); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.36s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 3738.43 // Query: FUN_001990-T1 [L=110] Description: FUN_001990 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (110 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 349 (0.0136622); expected 510.9 (0.02) Passed bias filter: 326 (0.0127618); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1116.08 // Query: FUN_001991-T1 [L=143] Description: FUN_001991 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (143 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1157 (0.0452926); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1411.01 // Query: FUN_001992-T1 [L=98] Description: FUN_001992 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (98 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 553 (0.0216481); expected 510.9 (0.02) Passed bias filter: 336 (0.0131533); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1001.68 // Query: FUN_001993-T1 [L=227] Description: FUN_001993 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.9e-15 55.6 0.0 5.8e-15 55.4 0.0 1.0 1 DUF6589 Family of unknown function (DUF6589) Domain annotation for each model (and alignments): >> DUF6589 Family of unknown function (DUF6589) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.4 0.0 2.3e-19 5.8e-15 65 245 .. 4 208 .. 2 224 .. 0.83 Alignments for each domain: == domain 1 score: 55.4 bits; conditional E-value: 2.3e-19 DUF6589 65 ktevypLptmdidessieGnadvledileqlgl..teeefe..........erlilvgGDqlTverlrslkkyraeddnsferldwllpipglfHl 148 k+ ++ Lp+++ ++++++++ + l+ +le l l ++e+e + ++++GD+l er+ ++kk +d+++er++ ++ +p+l+H+ FUN_001993-T1 4 KSCIVGLPVVPFNQNKVSDVCQYLQ-WLEDLLLkvFKKEDEppvtdasvleKVRVPLAGDLLGRERVTAAKKTPLGCDSAVERFENIVGCPALWHA 98 6778889******************.9996665113344447999999996666778*************************************** PP DUF6589 149 kmaalsaifethw.gspnsrdp.ssLghhatlLgrkpisnlkkpdfhtlrelifhvlearvldcwllvlgkdsleelaaskp....tlee...... 232 k +ls ++e+ + g+ ++ ++ ++L h ++ ++ + s + k++++++++l+ +a + +++++ +g d+l+ + a++p ++++ FUN_001993-T1 99 KQSFLSYVWEQLYsGTTSGGRDvGTLYHLRQNFRLVNVSHKVKKNYKSAESLMLSATKAYLCTAFKTWAGLDTLNGIPANLPklptSWDTfelkke 194 *************54444433579***99999866677777799*******************************999999999996666444445 PP DUF6589 233 .Leelaekivdrya 245 L +++ k vd+++ FUN_001993-T1 195 fLAKHIGKFVDEFI 208 56777777776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (227 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 513 (0.0200822); expected 510.9 (0.02) Passed bias filter: 459 (0.0179683); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2266.52 // Query: FUN_001994-T1 [L=166] Description: FUN_001994 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.37 10.9 5.0 0.65 10.1 5.0 1.4 1 GATA GATA zinc finger Domain annotation for each model (and alignments): >> GATA GATA zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 5.0 2.5e-05 0.65 10 32 .. 42 63 .. 41 67 .. 0.86 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 2.5e-05 GATA 10 plWRrgpngnktLCnaCglyykk 32 ++W + +++++ +Cn+Cg + FUN_001994-T1 42 KCWNSSGSKQC-VCNPCGRKIRN 63 58*********.******87776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (166 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1084 (0.0424349); expected 510.9 (0.02) Passed bias filter: 613 (0.0239969); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 1695.02 // Query: FUN_001995-T1 [L=620] Description: FUN_001995 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0014 19.1 59.5 0.0023 18.5 59.5 1.2 1 TFIIA Transcription factor IIA, alpha/beta subunit Domain annotation for each model (and alignments): >> TFIIA Transcription factor IIA, alpha/beta subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 59.5 8.9e-08 0.0023 49 364 .. 67 400 .. 54 407 .. 0.36 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 8.9e-08 TFIIA 49 dpkpeeaaspqqtlqlpkslkqala.apaaaapsqqsqapqsasqslpslvipasktlqfskssaataaslelpikveppiqv...gvtlqtasgp 140 dp+p + ++++ l+ ++ + + +a+ + ++p++ ++++ + +i++s a++e+ + +e++ + t+q+ + FUN_001995-T1 67 DPHPRQDENLESVPPLK----EKRVqSKTAKI--DKPRKPNQDKARQMKKTIDSSC----------ALAAQEIIAFTEYNNVFpsaSATQQQLQNR 146 33333333333333322....22210112211..1111122222222222222221..........222222222223211112121111111111 PP TFIIA 141 qeaelykqaqgaaqraaqplqqqv...gqgsaaqssinalqaq.sqqaqalaepqqqpkeqqqqqqqqqqqqqqqqqqqvqqqqqeqeqqaqqqgs 232 q++ + aq+ +q +++ + + + ++q+s++++++q +q++ + +pqqq+++++qq+ q+q++ qqqqq ++qqqq +++ ++q+++ FUN_001995-T1 147 QQKDDP-TAQQPQQLLQA----NSllqQAQDQHQQSVKPIEKQsEQSQYRQLQPQQQQPQKKQQK--QHQKE-QQQQQDQEQQQQLEYHDKRQEQQ 234 111111.22222222222....1133235677888899999887777777777777764433222..22222.22222222222222222222212 PP TFIIA 233 qvnnsqtdgaedaleeleaelaqrreagakkeelgreeidrllreqiaarakqeggglmlplkealkkkkkkkksrkkkkeveeass......... 319 + +++q+ + + +++ + +l++ ++++ ree++r ++ +++++ + pl++++k+k + ++++++ ++++s+ FUN_001995-T1 235 NGHQQQEHQRAMPTSQTHRQLSKPPSKNK-----YREEQRRC---NFPDQQHNYALQRLSPLQQQQKQKVWDHSTQRATLLRHHQSNssylnmled 322 22333333333333333333333333333.....33333333...233333333333455555555555555555444433333333446666662 PP TFIIA 320 .............................diesiaqlDGagddsdedeeseed...ddeEDaiNS.dLDDvddddddd 364 +++ DG d+s++++e +d dd+ ai d+DDv++++ + FUN_001995-T1 323 attvpstqgatssdavsclgttcsaitsaMTTLSDYADGFRDSSEDSDEGLQDfslDDSGVAISDrDIDDVNEMNHRE 400 222222222333345555555555555433333333455555555533334443333334466433666766665555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (620 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4863 (0.19037); expected 510.9 (0.02) Passed bias filter: 865 (0.0338618); expected 510.9 (0.02) Passed Vit filter: 322 (0.0126052); expected 25.5 (0.001) Passed Fwd filter: 70 (0.00274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.74u 0.43s 00:00:01.17 Elapsed: 00:00:00.45 # Mc/sec: 5608.63 // Query: FUN_001997-T1 [L=343] Description: FUN_001997 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.4e-06 27.1 0.3 3e-05 25.1 0.3 2.2 1 THAP THAP domain Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.3 1.2e-09 3e-05 18 59 .. 11 62 .. 2 104 .. 0.80 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 1.2e-09 THAP 18 vsfhrfP............kdkerrkkWlknikredlekkkkkksrvCskHFee 59 f+ fP + +rr +W++++++++l+ +++ + r+Cs HFe FUN_001997-T1 11 SDFFPFPqdnpnkyygagmSEWQRRLRWIAACRLDSLNVTRH-T-RICSVHFEG 62 56999999999999999988888999*********9999888.5.9******53 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (343 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 783 (0.0306518); expected 510.9 (0.02) Passed bias filter: 498 (0.019495); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3358.57 // Query: FUN_001998-T1 [L=59] Description: FUN_001998 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (59 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 381 (0.0149149); expected 510.9 (0.02) Passed bias filter: 340 (0.0133098); expected 510.9 (0.02) Passed Vit filter: 8 (0.000313173); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 604.27 // Query: FUN_001999-T1 [L=133] Description: FUN_001999 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (133 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 303 (0.0118614); expected 510.9 (0.02) Passed bias filter: 205 (0.00802505); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1342.41 // Query: FUN_002000-T1 [L=225] Description: FUN_002000 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 13.0 0.4 0.31 11.9 0.4 1.7 1 DUF3221 Protein of unknown function (DUF3221) 0.15 12.3 0.2 9.7 6.4 0.1 2.1 2 DUF829 Eukaryotic protein of unknown function 0.15 12.5 0.0 0.43 11.1 0.0 1.6 2 T26-6p_Ig-like_dom_2 T26-6p, second immunoglobulin-like doma Domain annotation for each model (and alignments): >> DUF3221 Protein of unknown function (DUF3221) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.4 3.7e-05 0.31 3 68 .. 94 160 .. 93 176 .. 0.67 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 3.7e-05 DUF3221 3 yviekeenriLvveeitkeeaenlseee..ieeykgeaiwllidkddvknlevGqkVrVwikgkiaeS 68 yv+++++++ ++ +++++ +++ +e + +e+ k+e l++++++k+++v+q V V i++S FUN_002000-T1 94 YVVNRNKKDAIWFRDYSEIDDAVETEVDfsYEKIKNELAA-LSNTSQLKEIKVFQLVMVRGMILIDKS 160 8999976666666665555544445555555555555555.59***************9876555555 PP >> DUF829 Eukaryotic protein of unknown function (DUF829) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.1 0.0011 9.7 196 235 .. 49 88 .. 43 95 .. 0.86 2 ? 4.9 0.0 0.0033 28 59 110 .. 136 183 .. 86 200 .. 0.63 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0011 DUF829 196 rdvesfieearqrgvsvdakkfedspHVahmrshpeeYvk 235 ++ e+f ++q++ sv+a++f+ + H ++ ++pe +++ FUN_002000-T1 49 KNSEYFTFVEQQKDSSVKAVCFSPKKHKSIVEQKPEICSP 88 56677777788899**********************9987 PP == domain 2 score: 4.9 bits; conditional E-value: 0.0033 DUF829 59 sesqreerkpvlfhvfSngGvllylallkalqeaesfkkllpkikGivfDSa 110 sq + + +f+ + ++G++l+ +++ ++ k l k++G+++D+ FUN_002000-T1 136 NTSQLK--EIKVFQLVMVRGMILIDKSE--RPQQIPGKANLTKVDGCFVDDF 183 222222..233999999***********..6778888888889*******85 PP >> T26-6p_Ig-like_dom_2 T26-6p, second immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 0.53 4.5e+03 30 47 .. 75 92 .. 52 140 .. 0.64 2 ? 11.1 0.0 5e-05 0.43 36 85 .. 167 216 .. 161 221 .. 0.89 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.53 T26-6p_Ig-like_dom_2 30 ykfvlvanPeylePlnvt 47 +k ++ +Pe P +vt FUN_002000-T1 75 HKSIVEQKPEICSPCKVT 92 444444555555555544 PP == domain 2 score: 11.1 bits; conditional E-value: 5e-05 T26-6p_Ig-like_dom_2 36 anPeylePlnvtieddfravvlreyddnsatvasktsgnfgdlgvlneva 85 + +l ++ + ddf +++ + ++++ v ++ nf++ + +++v FUN_002000-T1 167 PGKANLTKVDGCFVDDFSTIAITLWNEQICLVKVESIMNFKTCASKSTVE 216 55678999999*******************************99888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (225 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 888 (0.0347622); expected 510.9 (0.02) Passed bias filter: 524 (0.0205128); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2228.41 // Query: FUN_002001-T1 [L=263] Description: FUN_002001 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (263 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3736 (0.146252); expected 510.9 (0.02) Passed bias filter: 1030 (0.040321); expected 510.9 (0.02) Passed Vit filter: 85 (0.00332746); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.36u 0.42s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 2494.39 // Query: FUN_002002-T1 [L=310] Description: FUN_002002 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (310 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1294 (0.0506557); expected 510.9 (0.02) Passed bias filter: 784 (0.0306909); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3040.66 // Query: FUN_002003-T1 [L=389] Description: FUN_002003 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-22 79.0 0.1 5.3e-22 79.0 0.1 1.6 2 Pkinase Protein kinase domain 1.7e-18 67.3 0.0 2.6e-18 66.8 0.0 1.3 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.002 18.4 1.4 0.0021 18.3 0.0 1.7 2 APH Phosphotransferase enzyme family 0.0045 16.7 0.0 0.0077 15.9 0.0 1.3 1 ABC1 ABC1 atypical kinase-like domain 0.0058 16.8 0.1 0.014 15.6 0.1 1.7 1 YrbL-PhoP_reg PhoP regulatory network protein YrbL ------ inclusion threshold ------ 0.013 15.1 0.8 0.61 9.6 0.1 2.2 2 TCAD9 Ternary complex associated domain 9 0.043 13.9 0.1 0.043 13.9 0.1 2.0 2 RIO1 RIO domain 1.2 8.5 5.6 1.6 8.0 5.6 1.2 1 NatA_aux_su N-terminal acetyltransferase A, auxiliary sub Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 1.7 4.1 1.2e+04 22 48 .. 8 34 .. 5 43 .. 0.71 2 ! 79.0 0.1 1.9e-25 5.3e-22 4 186 .. 142 343 .. 139 376 .. 0.83 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 4.1 Pkinase 22 etgkivAiKkikkekakkkkekkvlrE 48 e+g+ Kk++ke++k ++e++ +E FUN_002003-T1 8 EKGRRLYFKKLRKEQKKRREEERKKSE 34 667777789999988888887555554 PP == domain 2 score: 79.0 bits; conditional E-value: 1.9e-25 Pkinase 4 leklGeGsfgkVykaveketgkivAiKkikkekakkkke....kkvlrEikilkklk.hpnivrlidvfeekdelylvlEyvegge..lfdlls.. 90 ++ l +G+fg +y a +g +vA+K++k ++++ k+v++E +i+ +l h+ + l+++ ++ + + +++ + ++ l+ + FUN_002003-T1 142 QKSLSSGAFGACYVAN--YRGMVVAVKELKVLGHSQQEIaqqrKEVIHEATIMLRLGdHRGLPLLFGIQSKVTPFRIIMQFHGINDksLTI--Rra 233 678899*******998..79********9987666655555689************99**********99977777777776555522443..223 PP Pkinase 91 .rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLidekge...lKitDFGlakelesssk.........ltsfvgtseYmAPEvl.ksk 172 rk ls+ee k+++ + + l+++Hs+gv+H DlK +NiL++++++ ++DFG ++ ++++ + ++++ +APE++ +++ FUN_002003-T1 234 vRKIKLSNEEWKTVVDLVGRVLQFIHSKGVLHNDLKGDNILLERREKhynPVVIDFGKSTFIDETPErkmcmstkeQKEYIKKYPHVAPEIVsGRS 329 58899**************************************555558899************9998999888877788888889******5556 PP Pkinase 173 kygkkvDvWslGvi 186 y+ ++D +s + + FUN_002003-T1 330 FYSIASDTYSFAKL 343 66********9755 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.8 0.0 9e-22 2.6e-18 1 193 [. 139 343 .. 139 383 .. 0.82 Alignments for each domain: == domain 1 score: 66.8 bits; conditional E-value: 9e-22 PK_Tyr_Ser-Thr 1 lelkeklGeGafGeVykgtlkeekekkkikVavKtlk.....eeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLk 89 ++l+++l +GafG y ++++ + VavK lk +++ ++++e+++ea++m +l +h+ + l g+ ++ p+ i++++ + + FUN_002003-T1 139 VKLQKSLSSGAFGACYVANYR------GMVVAVKELKvlghsQQEIAQQRKEVIHEATIMLRLgDHRGLPLLFGIQSKVTPFRIIMQFHGINDKS 227 5799*****************......999999999744333455556799*************************************9999888 PP PK_Tyr_Ser-Thr 90 efLrkk..keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse...kkvvkisDfGLardvekddyy......kkkekaklpikWmap 173 +r+ k kls +e ++ + + +++++sk ++H dl N+L+++ + + DfG + ++++ + k++++ ++ +ap FUN_002003-T1 228 LTIRRAvrKIKLSNEEWKTVVDLVGRVLQFIHSKGVLHNDLKGDNILLERrekHYNPVVIDFGKSTFIDETPERkmcmstKEQKEYIKKYPHVAP 322 888887446666777788888889*************************95443355689***999996555543454322233333456688** PP PK_Tyr_Ser-Thr 174 Eslkekk.ftsksDvWsfGvl 193 E+++ ++ ++ +sD +sf+ l FUN_002003-T1 323 EIVSGRSfYSIASDTYSFAKL 343 ****9997899*******865 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.0 8.1e-08 0.00023 115 173 .. 239 296 .. 224 305 .. 0.84 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 8.1e-08 Kdo 115 laeelrrallkavgrlirklhragvqHgdlyakhillqtekeeeakasliDldkarlrl 173 l++e + + vgr+ + +h+ gv H dl +ill+ ++ ++ ++iD+ k+ + FUN_002003-T1 239 LSNEEWKTVVDLVGRVLQFIHSKGVLHNDLKGDNILLERRE-KHYNPVVIDFGKSTFID 296 5566667788889***************************7.9***********98665 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.5 1.9 5.4e+03 129 160 .. 17 50 .. 3 60 .. 0.42 2 ! 18.3 0.0 7.6e-07 0.0021 137 200 .. 235 295 .. 213 298 .. 0.74 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 1.9 APH 129 rqleaaaarllaaelkd....rleeleeqllaalla 160 + + ++++r e k+ r+ +++e l + ++ FUN_002003-T1 17 KLRKEQKKRREE-ERKKseerRRKKFDE-LVDSIRS 50 222222221111.111112224555555.5444444 PP == domain 2 score: 18.3 bits; conditional E-value: 7.6e-07 APH 137 rllaaelkdrleeleeqllaallallpaelppvlvHgDlhpgNllvd....dggrvsGviDFedaglG 200 r+++ ++++ +++ l + l+ ++++H+Dl+ +N+l++ + ++v viDF+ +++ FUN_002003-T1 235 RKIKLSNEE--WKTVVDLVGRVLQFIH---SKGVLHNDLKGDNILLErrekHYNPV--VIDFGKSTFI 295 555556666..4444445666666666...69*****************8888888..*****98865 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 2.7e-06 0.0077 173 228 .. 247 305 .. 217 313 .. 0.80 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 2.7e-06 ABC1 173 aeklvelfleqifedgffhaDphpGNllvrkdg...elvllDfGlmgeldekfrkklae 228 + +lv +l+ i +g++h D+ N+l+++++ + v++DfG + +de +k++ FUN_002003-T1 247 VVDLVGRVLQFIHSKGVLHNDLKGDNILLERREkhyNPVVIDFGKSTFIDETPERKMCM 305 3456666789999****************988877899*************99999886 PP >> YrbL-PhoP_reg PhoP regulatory network protein YrbL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.1 4.9e-06 0.014 93 177 .. 227 313 .. 165 318 .. 0.74 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 4.9e-06 YrbL-PhoP_reg 93 aktleelvkkdeldkelkr....kLdefkeylldnhivindlsakNivlkrnsegeealvliDglGektliplaawsrvlnrrklerky 177 + t+++ v+k +l +e+ + ++ + ++ + + ++ ndl+ Ni+l+r++ +++++v+iD +G++t+i +++ k +++y FUN_002003-T1 227 SLTIRRAVRKIKLSNEEWKtvvdLVGRVLQFIHSKGVLHNDLKGDNILLERRE-KHYNPVVID-FGKSTFIDETPERKMCMSTKEQKEY 313 5555566655555554444000044455555666778999*********9975.667*****9.*******999998888888888887 PP >> TCAD9 Ternary complex associated domain 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.1 0.011 31 117 176 .. 31 102 .. 21 188 .. 0.67 2 ? 9.6 0.1 0.00022 0.61 298 322 .. 262 290 .. 252 294 .. 0.89 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.011 TCAD9 117 deaaeravealdrlletllkvlyraatveslkslree....lnerLG....pelrvevdevdaagl....lv 176 ++ er ++++d+l++ ++++l ++ +e+++ ++e l+ rLG + l ++ ++ ++++ v FUN_002003-T1 31 KKSEERRRKKFDELVDSIRSRLAKGEEPEPDPGSLELfdadLEVRLGnhpqKTLPLPCEKASENSSstvaNV 102 33458999****************************955666666665544333333333222222444422 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00022 TCAD9 298 asvHGDLNprNvLla....ednvyLIDya 322 ++ H DL ++N+Ll n+ +ID+ FUN_002003-T1 262 GVLHNDLKGDNILLErrekHYNPVVIDFG 290 789************9988889******6 PP >> RIO1 RIO domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 2.2 2.8 7.9e+03 24 47 .. 14 37 .. 7 50 .. 0.48 2 ? 13.9 0.1 1.5e-05 0.043 83 156 .. 216 297 .. 162 306 .. 0.75 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 2.8 RIO1 24 eFkkvkkyrsgdkrfkarksktsw 47 Fkk +k +++ ++ + +ks+ + FUN_002003-T1 14 YFKKLRKEQKKRREEERKKSEERR 37 455543333333332222222222 PP == domain 2 score: 13.9 bits; conditional E-value: 1.5e-05 RIO1 83 lvmefigkdgveap...klkdve.eeeaeelyeevleemrklykeaglvHgDLseyNvlvded....kvviIDvsQaveldh 156 ++m+f g ++ ++ +++++ ++e ++ + +++ + ++++ g+ H DL N+l+++ ++v+ID++ ++ +d+ FUN_002003-T1 216 IIMQFHGINDKSLTirrAVRKIKlSNEEWKTVVDLVGRVLQFIHSKGVLHNDLKGDNILLERRekhyNPVVIDFGKSTFIDE 297 67777653333332011234444755677777788888999******************98643225689****99887665 PP >> NatA_aux_su N-terminal acetyltransferase A, auxiliary subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 5.6 0.00058 1.6 406 468 .. 7 69 .. 1 76 [. 0.79 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00058 NatA_aux_su 406 seaerkklrkkakkeekkaekeeaekaekkkkkkaaekkakkedeeakkededplgekLvkte 468 e+ r+ + kk++ke+kk+++ee +k+e++++kk e + + ak e+++p++ +L+ + FUN_002003-T1 7 REKGRRLYFKKLRKEQKKRREEERKKSEERRRKKFDELVDSIRSRLAKGEEPEPDPGSLELFD 69 4555666789******99999999999999999988888888889999999999888887555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (389 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2083 (0.0815424); expected 510.9 (0.02) Passed bias filter: 1178 (0.0461147); expected 510.9 (0.02) Passed Vit filter: 125 (0.00489333); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.36u 0.41s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 3790.18 // Query: FUN_002004-T1 [L=104] Description: FUN_002004 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0026 18.5 0.0 0.0026 18.5 0.0 1.1 1 EndoU_bacteria Bacterial EndoU nuclease 0.0047 16.8 0.2 0.005 16.8 0.2 1.1 1 DUF6649 Family of unknown function (DUF6649) Domain annotation for each model (and alignments): >> EndoU_bacteria Bacterial EndoU nuclease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 2.1e-07 0.0026 43 102 .. 31 93 .. 5 104 .] 0.71 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 2.1e-07 EndoU_bacteria 43 pngvYtagveikkvgtktvad....gekkstfFPktwsaeeilaevteayknrknkegarnqa.v 102 p t+ ve ++ + +++ +ek +++FP+t+++ee++ + ++ + r+ + rn++ v FUN_002004-T1 31 PAPLHTMLVEKE-SKEEAITKcrqrKEKDTVMFPSTCTEEELHPSTERTIRARRATHC-RNHYgV 93 555667777777.4444456678899**********************9998888877.554333 PP >> DUF6649 Family of unknown function (DUF6649) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.2 3.9e-07 0.005 148 209 .. 33 95 .. 8 103 .. 0.73 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 3.9e-07 DUF6649 148 pslsvpveqdnvrkailearqrakekatanppssptradghppeeqietah.g.ydspdyglde 209 p ++ ve++ ai ++rqr kek t ps+ t + hp e+ a + yg+ + FUN_002004-T1 33 PLHTMLVEKESKEEAITKCRQR-KEKDTVMFPSTCTEEELHPSTERTIRARrAtHCRNHYGVSK 95 4456789**************9.9******************9887554431213345677655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1842 (0.072108); expected 510.9 (0.02) Passed bias filter: 983 (0.0384811); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1026.35 // Query: FUN_002005-T1 [L=164] Description: FUN_002005 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.017 15.5 0.1 0.026 14.9 0.1 1.3 1 P2RX7_C P2X purinoreceptor 7 intracellular domain 0.14 11.9 0.2 0.13 12.0 0.2 1.0 1 BUD22 BUD22 Domain annotation for each model (and alignments): >> P2RX7_C P2X purinoreceptor 7 intracellular domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.1 2.1e-06 0.026 66 98 .. 70 104 .. 25 108 .. 0.70 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 2.1e-06 P2RX7_C 66 eaeakseserpaWCkCgkCrpsqlp..qEelCCRr 98 ea+ +++ + aWC Cg C+ +l+ +E CC++ FUN_002005-T1 70 EARFENRVSVDAWCLCGLCKTETLVgtREYRCCKE 104 33444446789*********999988899999985 PP >> BUD22 BUD22 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.2 1e-05 0.13 173 231 .. 5 68 .. 1 120 [. 0.68 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 1e-05 BUD22 173 dkedessdsedekeeseddeeeeeeeedeedaeddeeeeeedlsqydglla.....sddeded.....n 231 d++++ss+s e+ e++ee+ +e + ++ +++e ++q ++++ sddeded FUN_002005-T1 5 DSNSASSSS----EDPEQNEESGIDELEVRIRPA-LPYQDEPVAQVAARMGedemySDDEDEDgispaT 68 223333333....335555555555555444443.456677777777766668888******9544440 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (164 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 763 (0.0298689); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1617.95 // Query: FUN_002006-T1 [L=331] Description: FUN_002006 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-11 45.2 1.1 4.9e-11 43.7 1.1 1.8 1 THAP THAP domain ------ inclusion threshold ------ 0.16 12.8 0.2 0.28 12.0 0.2 1.4 1 DUF2992 Protein of unknown function (DUF2992) Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.7 1.1 3.9e-15 4.9e-11 5 84 .. 23 101 .. 14 103 .. 0.80 Alignments for each domain: == domain 1 score: 43.7 bits; conditional E-value: 3.9e-15 THAP 5 gCknkskskskkk..vsfhrfPkdkerrkkWlknikredlekkkkkksrvCskHFeee..lekeedeekrskkrrrLkpdavPt 84 +C+n s + +s+h fP dke+++kW ++++++ + k+ k s +Cs+H+e++ ++ + e ++ +rr+L ++++P+ FUN_002006-T1 23 SCTNMSY-----SpgISMHIFPSDKELCQKWTSFVRKHRPNFKPLKYSALCSAHYEPTcfTQVASIESSNCARRRTLEKGSIPS 101 5777333.....1349*******************9987776666448**********995555667788999999*******8 PP >> DUF2992 Protein of unknown function (DUF2992) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.2 2.2e-05 0.28 38 113 .. 191 263 .. 168 276 .. 0.75 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.2e-05 DUF2992 38 vlefilkklselkfskpaeaeekkekkinpKrlqReikkelkkkgvgtkAqealkleleerkkerkkeskekreae 113 ef + s+ + +++++ ++ k++ +rlq++++k + k+ v kA ea+ ++ e +++++ +++ ++ +e FUN_002006-T1 191 CEEFSPSPASSTEVHPCSRCAD---LKVKNRRLQKKVSKLKAKNCVLKKAREAIVNSDELSNSNHDDDTRPAESNE 263 5555555555555554444444...56999*****************************99999888888776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (331 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1404 (0.0549618); expected 510.9 (0.02) Passed bias filter: 725 (0.0283813); expected 510.9 (0.02) Passed Vit filter: 89 (0.00348405); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3263.43 // Query: FUN_002007-T1 [L=159] Description: FUN_002007 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (159 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 526 (0.0205911); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.38 # Mc/sec: 1664.48 // Query: FUN_002008-T1 [L=204] Description: FUN_002008 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.1 8.7 5.6 0.2 11.1 0.1 1.9 2 Piezo_TM25-28 Piezo TM25-28 Domain annotation for each model (and alignments): >> Piezo_TM25-28 Piezo TM25-28 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 7.7e-06 0.2 208 319 .. 6 119 .. 2 127 .. 0.71 2 ? -0.3 1.8 0.023 5.8e+02 208 237 .. 162 192 .. 119 204 .] 0.46 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 7.7e-06 Piezo_TM25-28 208 eekksleqlkrqmerikakqkkvkeakesseseeeekepeee.eek.aeeekekkekkkwwrpwldhasvvrsgdyylfesdseeeeeeaeeeeek 301 ee+k + ++k e +k+ ++vk+ ++++ + + ++++ ++ ++++ +++ k+ + + ++ s++y ++ s++e+ ++++ e++ FUN_002008-T1 6 EEEKDVLAMKAMAEDLKEGIDQVKKDNSQTGRVAFAVTKSLTfGKNvKKRRGQRTLAKTLALDRHNISPLLPSANYQVLLSNEEDILDSQDYYESE 101 5777888888888888888777777777766654333333332222133333333344444444555679*************9999999****** PP Piezo_TM25-28 302 pkkksafqlayqaWvtda 319 k+ fql+ + W+t a FUN_002008-T1 102 CKRIDDFQLTIEQWITTA 119 ***************987 PP == domain 2 score: -0.3 bits; conditional E-value: 0.023 Piezo_TM25-28 208 eekksleql.krqmerikakqkkvkeakess 237 +e sl++ q + ++ kq+++k+++ ++ FUN_002008-T1 162 AEAASLRKQqALQEKELRLKQQETKRQQLHE 192 2222322210122233444444443333222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (204 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1938 (0.0758661); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2038.72 // Query: FUN_002009-T1 [L=144] Description: FUN_002009 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 480 (0.0187904); expected 510.9 (0.02) Passed bias filter: 418 (0.0163633); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1469.91 // Query: FUN_002010-T1 [L=170] Description: FUN_002010 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.029 15.0 0.0 5.2 7.7 0.0 2.3 2 Nbs1_C DNA damage repair protein Nbs1 Domain annotation for each model (and alignments): >> Nbs1_C DNA damage repair protein Nbs1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 0.0 0.00021 5.2 8 34 .. 46 72 .. 42 75 .. 0.87 2 ? 5.1 0.0 0.0014 35 30 49 .. 95 114 .. 79 124 .. 0.78 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.00021 Nbs1_C 8 KkayPGadglpkiIgGsDLlvhnagkn 34 K +yPG g+ k I G D ++ + +++ FUN_002010-T1 46 KGQYPGHTGVRKRIQGRDVITLQMSQD 72 789*****************9987765 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0014 Nbs1_C 30 nagknseleeWlkeaveeek 49 +++k + e Wl+++ e++ FUN_002010-T1 95 HKKKVDDSESWLRQEEPEKN 114 556777899*****987776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (170 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 691 (0.0270503); expected 510.9 (0.02) Passed bias filter: 349 (0.0136622); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1740.49 // Query: FUN_002011-T1 [L=179] Description: FUN_002011 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-52 179.1 0.1 1.4e-52 178.8 0.1 1.1 1 rva_4 Integrase core domain 0.002 18.9 0.0 0.0042 17.8 0.0 1.6 2 rve Integrase core domain ------ inclusion threshold ------ 0.021 15.5 0.2 0.086 13.6 0.0 2.1 3 HTH_21 HTH-like domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 178.8 0.1 1.6e-56 1.4e-52 2 111 .. 68 179 .] 67 179 .] 0.97 Alignments for each domain: == domain 1 score: 178.8 bits; conditional E-value: 1.6e-56 rva_4 2 ykvatPnslWhidgnmklirWrlvvhGaidgysrlivyleastnnrastvlkqflkavkkyglPsrvrsdkggenvkvallm..nllrGlerssvi 95 y+va P +lWhidgn+klirWr+v+hG+i+g+sr+ivyl+++tnnra+tv + f+ a+++yglPsrvrsdkggenv val+m + lrG +r+s+i FUN_002011-T1 68 YQVASPLALWHIDGNHKLIRWRFVIHGGINGFSRMIVYLQCNTNNRAATVPRLFQGATETYGLPSRVRSDKGGENVMVALYMlnHPLRGPDRGSHI 163 9********************************************************************************943458********* PP rva_4 96 tGrsvhnqrierlWrd 111 GrsvhnqrierlWrd FUN_002011-T1 164 AGRSVHNQRIERLWRD 179 **************98 PP >> rve Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 4.9e-07 0.0042 4 80 .. 73 144 .. 70 152 .. 0.88 2 ? -3.7 0.0 2.5 2.1e+04 73 84 .. 158 169 .. 157 172 .. 0.78 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 4.9e-07 rve 4 pnqlwqgDityikvpgkggklyllvivDdfsreivawalssemsaetvlaalekaiakrggvkpkiihsDngsefts 80 p lw++D + ++ ++ ++ + fsr+iv ++ ++++a+tv ++ + a + +g p +++sD g e ++ FUN_002011-T1 73 PLALWHIDGNHKL-IRW--RFVIHGGINGFSRMIVYLQCNTNNRAATVPRLFQGATETYGL--PSRVRSDKGGENVM 144 7789999999766.334..599999************************************..9********98775 PP == domain 2 score: -3.7 bits; conditional E-value: 2.5 rve 73 Dngseftskefq 84 D+gs+++ ++++ FUN_002011-T1 158 DRGSHIAGRSVH 169 999999888765 PP >> HTH_21 HTH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 1e-05 0.086 4 49 .. 3 47 .. 2 49 .. 0.85 2 ? -3.2 0.0 1.8 1.5e+04 12 23 .. 119 130 .. 114 132 .. 0.75 3 ? -3.8 0.1 2.6 2.3e+04 42 48 .. 172 178 .. 171 178 .. 0.76 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1e-05 HTH_21 4 dellel.IkeifeesrgtYGyRritaeLrreggirvnrkrVaRLMre 49 de+l++ I+ i ++ + Gy+r+t Lr++ gi +r++ Mr+ FUN_002011-T1 3 DEDLDAvINSILNDF-PETGYKRMTGFLRAR-GIVLQQNRIREAMRR 47 445666599999998.9**************.798*******99996 PP == domain 2 score: -3.2 bits; conditional E-value: 1.8 HTH_21 12 eifeesrgtYGy 23 ++f+ tYG FUN_002011-T1 119 RLFQGATETYGL 130 678877889996 PP == domain 3 score: -3.8 bits; conditional E-value: 2.6 HTH_21 42 rVaRLMr 48 r++RL r FUN_002011-T1 172 RIERLWR 178 8888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 401 (0.0156978); expected 510.9 (0.02) Passed bias filter: 381 (0.0149149); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1774.59 // Query: FUN_002012-T1 [L=149] Description: FUN_002012 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-17 63.4 0.0 4.2e-17 63.0 0.0 1.2 1 rva_4 Integrase core domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 63.0 0.0 1.6e-21 4.2e-17 127 192 .. 1 66 [. 1 69 [. 0.94 Alignments for each domain: == domain 1 score: 63.0 bits; conditional E-value: 1.6e-21 rva_4 127 ledseildidndihllalhivylpriqkeleefknawnnhklrteknktPlqlfveglleniesns 192 +e +il+++n++hl+alh+v++pri+++l+ f++a+n+ +l+te+ +P+ql+++g+l +s++ FUN_002012-T1 1 MESCGILEPSNELHLFALHYVFVPRINRNLQMFQEAYNRAPLSTERGCSPTQLWIRGMLGVAQSQQ 66 78889******************************************************8777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (149 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 413 (0.0161675); expected 510.9 (0.02) Passed bias filter: 381 (0.0149149); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1498.41 // Query: FUN_002013-T1 [L=619] Description: FUN_002013 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-12 48.4 0.6 1.3e-11 45.2 0.0 2.4 3 HECT HECT-domain (ubiquitin-transferase) 0.0055 17.1 0.1 0.018 15.5 0.1 1.9 1 DUF5126 Domain of unknown function (DUF5126) ------ inclusion threshold ------ 0.015 15.7 2.8 0.015 15.7 2.8 1.9 3 MFAP1 Microfibril-associated/Pre-mRNA processing 1.6 9.4 15.1 0.34 11.5 3.1 3.9 4 ABC_tran_Xtn ABC transporter 4.7 7.6 12.8 0.19 12.1 1.5 2.7 3 Sipho_Gp157 Siphovirus Gp157 Domain annotation for each model (and alignments): >> HECT HECT-domain (ubiquitin-transferase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.5 0.13 6.6e+02 79 169 .. 108 204 .. 83 211 .. 0.65 2 ? -3.0 0.0 1.2 6.1e+03 232 242 .. 237 247 .. 235 254 .. 0.83 3 ! 45.2 0.0 2.4e-15 1.3e-11 37 305 .. 344 617 .. 310 619 .] 0.80 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.13 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 79 dleeidpelakslksLlelkedeeevedleltFtvsee..sfgekktveLipnGsn...........ipVtnenveeYiklvvdyrlnksiekqle 161 + e+ +l + l +L+ ++++ev+ ++ F++ e + g ++ Li+n + + t e+++++ik + d l ++q++ FUN_002013-T1 108 SVMELTAKLTQLLVNLRAK-TNNKEVKPYMCVFSAFLEtrNKG---ETTLIRNRKRkqkkrekhrkrFQKTIESRKQHIKNLSDKQL---TDEQIS 196 3667778888888888855.45556888889999443311444...44677773332344555555566677888888888887777...677777 PP xxxxxxxx RF HECT 162 afrkGfss 169 + +G++ FUN_002013-T1 197 LLSRGLKF 204 77777765 PP == domain 2 score: -3.0 bits; conditional E-value: 1.2 xxxxxxxxxxx RF HECT 232 rrklLkFvTgs 242 +++l+kFvTg FUN_002013-T1 237 QEALMKFVTGA 247 789******96 PP == domain 3 score: 45.2 bits; conditional E-value: 2.4e-15 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx..xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx RF HECT 37 lelfkllGkllGkaiyegllldlpfpraflkkllg.kekltled..leei.dpelakslksLlelkedeeevedleltFtvseesfgek.ktveLi 127 + +f l+Gk++ ++++++ l +++a++ +++ +++ le+ le+i dp l + lk+L + +++e+ +Ft + g+ L+ FUN_002013-T1 344 SCFFVLVGKMVVHSFINECK-RLGISPAVISYIITgSRDTALEHlvLEDIpDPCLRQILKELMDC--SDQELG----KFTSD----GDFnIADTLV 428 34689999999999999875.7899999999998875566666655778879**********966..443343....57755....3331223588 PP xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxx.xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 128 pnG.snipVtnenveeYiklvvdyrlnksiekqleafrkGfssvi..pkealklftpe.elellicGsee.vidvedlkkntkyeggytkeskvik 218 G +i+V +n++ + v + + ++ + l +rkG+ sv + l++++ ++++li +e +i+v++l++ +ky+++ ++ + + FUN_002013-T1 429 SAGfPHIEVLLSNRSLAYECVLTHEVVTKRIPVLGDLRKGLDSVRvmATTGTDLVQQHpQVQQLIFPAAEsKIEVSELRQLIKYNQTDGSTAEAAE 524 887257*********999999999999***************9754377888888765489*****999999************99888999**** PP xxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx.xxx RF HECT 219 wfweileefseeerrk........lLkFvTgssrlPlgGfkslpkltIqkksgkdddrLPtahTCfnlLklpeYss.keilkekLliAieeg.egF 304 +f ++l+e+++ + +k lL+ +Tg + lP+ + k+ +++ ++++++ L +a TCf+ Lk+ Y + +e++ + + ++i++g gF FUN_002013-T1 525 YFEKYLDELNTRDDSKdeetvgggLLQLWTGWPSLPMI--E--DKMIVAFLAKTSNKVLAEADTCFKSLKIATYHTeYENFVKYMDLSISHGkVGF 616 ********8877666556777777************99..3..478999999999*******************863699************8899 PP x RF HECT 305 g 305 g FUN_002013-T1 617 G 617 7 PP >> DUF5126 Domain of unknown function (DUF5126) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.1 3.5e-06 0.018 9 64 .. 42 96 .. 37 111 .. 0.87 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 3.5e-06 DUF5126 9 reslkveetFGGvnvsfkNpkkanlaievvkkdaegkewkeveavYtaaeegkfsv 64 +++++ + +F G v+f+N ++l+i++ k ++ +k k +++ +t++ + +v FUN_002013-T1 42 KSDISSKHDFVGALVKFHNRRVEKLTIKLRKLEQAKK-HKRNNMDFTKNVKPVTTV 96 578999**************************99999.59*******987766655 PP >> MFAP1 Microfibril-associated/Pre-mRNA processing # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.3 0.9 4.6e+03 96 115 .. 69 88 .. 59 115 .. 0.60 2 ? 15.7 2.8 2.9e-06 0.015 23 100 .. 152 234 .. 128 238 .. 0.76 3 ? -4.1 0.6 3.2 1.7e+04 60 88 .. 513 541 .. 496 544 .. 0.45 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.9 MFAP1 96 klReLkRikrdreerearek 115 klR L+ k+++++ k FUN_002013-T1 69 KLRKLEQAKKHKRNNMDFTK 88 55555555555554444444 PP == domain 2 score: 15.7 bits; conditional E-value: 2.9e-06 MFAP1 23 etikekeklekeeeeeeeeekkeeeerkkeakklveeeikkeaaekeae......deeeeeeevddtDeldpeaeyeaWklReL 100 + i+++++++k++e+++++ +k+ e rk++ k+l +++++ e+ + ++ + +++ee +d+D++d ++ aW lR L FUN_002013-T1 152 TLIRNRKRKQKKREKHRKRFQKTIESRKQHIKNLSDKQLTDEQISLLSRglkfipT-PATNEEDEDEDNTDGNTPLSAWGLRKL 234 33445777777778888888899999999999999999999998865555666643.33448889999999***********98 PP == domain 3 score: -4.1 bits; conditional E-value: 3.2 MFAP1 60 eikkeaaekeaedeeeeeeevddtDeldp 88 + + ++++ae e+ +e++++D+ + FUN_002013-T1 513 NQTDGSTAEAAEYFEKYLDELNTRDDSKD 541 33333333333333333355555555443 PP >> ABC_tran_Xtn ABC transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.16 8.3e+02 11 48 .. 51 88 .. 46 111 .. 0.78 2 ? 11.5 3.1 6.7e-05 0.34 4 49 .. 128 173 .. 125 192 .. 0.82 3 ? 2.2 0.1 0.054 2.8e+02 38 78 .. 501 541 .. 483 545 .. 0.83 4 ? 0.3 0.1 0.21 1.1e+03 7 20 .. 590 603 .. 586 607 .. 0.86 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.16 ABC_tran_Xtn 11 YkGnYskfleqkeerleqqekayekqqkeikkleefIr 48 + G kf + + e+l +++++ e+ +k ++ ++f + FUN_002013-T1 51 FVGALVKFHNRRVEKLTIKLRKLEQAKKHKRNNMDFTK 88 66777788888999999999999988888888888865 PP == domain 2 score: 11.5 bits; conditional E-value: 6.7e-05 ABC_tran_Xtn 4 ergklttYkGnYskfleqkeerleqqekayekqqkeikkleefIrr 49 ++++++ Y +s+fle++++ + + + ++++qk+++k ++ ++ FUN_002013-T1 128 NNKEVKPYMCVFSAFLETRNKGETTLIRNRKRKQKKREKHRKRFQK 173 7899********************9999999999999887654444 PP == domain 3 score: 2.2 bits; conditional E-value: 0.054 ABC_tran_Xtn 38 keikkleefIrrfrakaskakqaqsrekaLeklekiekpee 78 e+++l++ I+ ++ +s+a +a+ ek L+ l + +++ FUN_002013-T1 501 IEVSELRQLIKYNQTDGSTAEAAEYFEKYLDELNTRDDSKD 541 5788999**************************88877743 PP == domain 4 score: 0.3 bits; conditional E-value: 0.21 ABC_tran_Xtn 7 klttYkGnYskfle 20 k+ tY+ Y++f++ FUN_002013-T1 590 KIATYHTEYENFVK 603 899*********98 PP >> Sipho_Gp157 Siphovirus Gp157 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.4 0.021 1.1e+02 32 81 .. 39 88 .. 27 107 .. 0.90 2 ? 12.1 1.5 3.7e-05 0.19 3 82 .. 110 187 .. 108 209 .. 0.88 3 ? -2.4 0.3 1.1 5.6e+03 17 42 .. 515 541 .. 504 545 .. 0.67 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.021 Sipho_Gp157 32 esleeeleeKaenvakviknleaeaeaikaekkrLeerkkalenrvkrLK 81 e +++++ +K + v +++k + ++e + + ++Le+ kk + n+++ K FUN_002013-T1 39 EDFKSDISSKHDFVGALVKFHNRRVEKLTIKLRKLEQAKKHKRNNMDFTK 88 6678999***********************************99987665 PP == domain 2 score: 12.1 bits; conditional E-value: 3.7e-05 Sipho_Gp157 3 YelaadyeellelleeedeeleeaiadtLesleeeleeKaenvakviknleaeaeaikaekkrLeerkkalenrvkrLKe 82 el+a++ +ll +l +++ + ++++ ++ +++ le++ ++ +i+n++ + + +++++kr+++ ++ ++++k+L + FUN_002013-T1 110 MELTAKLTQLLVNLRAKTNN--KEVKPYMCVFSAFLETRNKGETTLIRNRKRKQKKREKHRKRFQKTIESRKQHIKNLSD 187 58999999999999888866..589999999999999999***************************9999999999965 PP == domain 3 score: -2.4 bits; conditional E-value: 1.1 Sipho_Gp157 17 eeedeele.eaiadtLesleeeleeKa 42 ++ ++ ++ e ++++L++l++ ++K FUN_002013-T1 515 TDGSTAEAaEYFEKYLDELNTRDDSKD 541 556666666899999999997777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (619 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2482 (0.0971619); expected 510.9 (0.02) Passed bias filter: 917 (0.0358974); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 5953.81 // Query: FUN_002014-T1 [L=253] Description: FUN_002014 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0051 16.1 3.7 0.0074 15.5 3.7 1.2 1 Ndc1_Nup Nucleoporin protein Ndc1-Nup ------ inclusion threshold ------ 0.14 12.1 0.6 8.1 6.4 0.0 2.0 2 PFF1_TM Vacuolar membrane protease, transmembrane domain Domain annotation for each model (and alignments): >> Ndc1_Nup Nucleoporin protein Ndc1-Nup # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 3.7 5.8e-07 0.0074 338 438 .. 23 140 .. 20 175 .. 0.69 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 5.8e-07 Ndc1_Nup 338 eClsvikelttrinaygq.papkaaps...kkaqkqkasapvkelprls.aplkednifgn.............slsaeatpkskssrkegvekav 415 +C+s+++e+++ i+a++ p+ + ++ +++ + + s++ + p+++ ++ ++ +++n s+++ ++p+ k+ r+++v++++ FUN_002014-T1 23 RCISLLQEVKDLIEARSSgPENTDETAafsSSKRQARLSSSTRTVPQQQeNNTTQQRVMQNfrslfapysaacsSSASARPPAAKKPRTSQVRETW 118 7*****************6555555447763334444444555555555333333445555666666699999877777777888899******99 PP Ndc1_Nup 416 ssvakspgqsspaarlsprakkl 438 + + g s++a ++s+ra+k FUN_002014-T1 119 THDFFCLG-STQAVSVSSRAQKI 140 99998888.44555555444443 PP >> PFF1_TM Vacuolar membrane protease, transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.6 0.0036 46 158 241 .. 42 125 .. 25 154 .. 0.60 2 ? 6.4 0.0 0.00063 8.1 95 145 .. 199 249 .. 197 253 .] 0.83 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.0036 PFF1_TM 158 pedqeeaeeddeesveddnestteanptentnegeqsdseeeeederapllegssskesgkskkeqswskkllnytWliQfLll 241 pe+++e+++ +++ +++ +s+t++ p++++n+ +q + ++ ++ ap + ss+ s +++ + + tW f +l FUN_002014-T1 42 PENTDETAAFSSSKRQARLSSSTRTVPQQQENNTTQQRVMQNFRSLFAPYSAACSSSASARPPAAKKPRTSQVRETWTHDFFCL 125 344444444445555556666666666666666666666666666666666553333332222222223334455666666665 PP == domain 2 score: 6.4 bits; conditional E-value: 0.00063 PFF1_TM 95 tgvYpltilyllaslasllellalsfklkkkkklarekkdsssnyssesqi 145 g+Y++++l +a l+ l ++ k k+++++ r++++++++++++ q+ FUN_002014-T1 199 SGGYSVAFLRDAAGLGQALAYIRSLQKDKRASSQHRKDHKDHATKRQRRQQ 249 599********************9999999999888888888766665554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (253 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1663 (0.0651008); expected 510.9 (0.02) Passed bias filter: 672 (0.0263065); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.24u 0.47s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 2533.94 // Query: FUN_002015-T1 [L=402] Description: FUN_002015 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0062 17.0 0.3 0.012 16.0 0.3 1.5 1 DUF501 Protein of unknown function (DUF501) Domain annotation for each model (and alignments): >> DUF501 Protein of unknown function (DUF501) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.3 4.9e-07 0.012 36 134 .. 225 323 .. 223 328 .. 0.70 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 4.9e-07 DUF501 36 PelvkavsrLEaeglikaleeklaedeelaeayeaaheeyaakReell...seeereeleeeseekeleevgvgGirklervKCLHahvAdyLage 128 P+l+ ++++LE++ i+++ e+++ de+la++ e++ +++ + ++ + +er++++ e+ ++ +e +++G + e++ H+ v + L++ FUN_002015-T1 225 PHLAPKCAKLENDTAITKVGEQIQLDEQLAREIESQLNQEFLQDHQNCdnlTMQERSHCQVEQ--EKDAEQSTSGQLTTEKILSDHVSVVKELSN- 317 99******************************9987665555444444111555555554333..444667777766677777777777777776. PP DUF501 129 gkNpvG 134 ++ +G FUN_002015-T1 318 RVDDIG 323 555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (402 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1571 (0.0614993); expected 510.9 (0.02) Passed bias filter: 760 (0.0297514); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3930.83 // Query: FUN_002016-T1 [L=479] Description: FUN_002016 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (479 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 842 (0.0329614); expected 510.9 (0.02) Passed bias filter: 599 (0.0234488); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 4702.94 // Query: FUN_002017-T1 [L=116] Description: FUN_002017 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 414 (0.0162067); expected 510.9 (0.02) Passed bias filter: 383 (0.0149931); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.34s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1208.00 // Query: FUN_002019-T1 [L=280] Description: FUN_002019 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (280 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1071 (0.041926); expected 510.9 (0.02) Passed bias filter: 678 (0.0265414); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.34s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2804.99 // Query: FUN_002020-T1 [L=234] Description: FUN_002020 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 2 7.1 4.3 2.5 6.7 4.3 1.1 1 CDC45 CDC45 Domain annotation for each model (and alignments): >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 4.3 9.9e-05 2.5 130 227 .. 39 132 .. 9 139 .. 0.49 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 9.9e-05 CDC45 130 eedeedeeeeeeddeeeeeeeeeeedeeeeeedeeeskkkrksesdeeee.eeddeeersrkrrrseesakklrkq..lkkerreyeavlekyYsq 222 +++ +d+ ++++++++e++ + d+ ++ d+++s ++ ++ +e+e e+dde+ + +++ + +k++++ ++++ + ++l+k +++ FUN_002020-T1 39 KTNTKDD--PIQESDSSDDESDADFDNAGTDYDSDTS--HD-EWVPDEDEvESDDENPGNYPKSEIN--WRKETEElyKESKSIVFDSQLNKLFQR 127 3332222..2222222222222222222323333222..22.2333333324444444444444444..444444434555666677788888888 PP CDC45 223 gtsyg 227 ++s g FUN_002020-T1 128 CQSCG 132 88776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (234 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1102 (0.0431396); expected 510.9 (0.02) Passed bias filter: 692 (0.0270894); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 2384.36 // Query: FUN_002021-T1 [L=125] Description: FUN_002021 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-18 66.2 2.4 4.5e-18 66.2 2.4 1.5 2 THAP THAP domain ------ inclusion threshold ------ 0.03 14.8 0.0 0.042 14.3 0.0 1.3 1 Lin-15B Lin-15B-like domain Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.2 2.4 3.5e-22 4.5e-18 1 86 [] 4 94 .. 4 94 .. 0.90 2 ? -2.4 0.0 0.91 1.2e+04 30 40 .. 106 116 .. 97 120 .. 0.61 Alignments for each domain: == domain 1 score: 66.2 bits; conditional E-value: 3.5e-22 THAP 1 CavpgCknkskskskkkvsfhrfP.kdkerrkkWlknikredlekkkk.kksrvCskHFeee...lekeedeekrskkrrrLkpdavPtlf 86 C++pgC+n+s+++++k++ f+++P ++k++ kkWl++++r+++ +kk ++ +vC++HF+e+ +++ + ++++rrLk+davP +f FUN_002021-T1 4 CSAPGCSNRSDKDPEKRLNFYNLPfRNKKLAKKWLDQLRRDSRFLTKKlENVYVCNEHFTEHcyeVSHRYEMLGAKTRKRRLKQDAVPKIF 94 *********99999999********99*************998888886558*******9999995555677788889999********98 PP == domain 2 score: -2.4 bits; conditional E-value: 0.91 THAP 30 rkkWlknikre 40 ++W+++ +r+ FUN_002021-T1 106 SERWIAQRERK 116 36888776665 PP >> Lin-15B Lin-15B-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 3.3e-06 0.042 44 68 .. 46 71 .. 39 114 .. 0.69 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 3.3e-06 Lin-15B 44 ksllkk.ekiyvCrsHfketideifk 68 + l kk e+ yvC++Hf+e + e+ FUN_002021-T1 46 RFLTKKlENVYVCNEHFTEHCYEVSH 71 34455589************998843 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (125 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1032 (0.0403993); expected 510.9 (0.02) Passed bias filter: 624 (0.0244275); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1232.27 // Query: FUN_002022-T1 [L=233] Description: FUN_002022 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.4e-11 42.0 2.8 2.3e-10 40.8 2.8 1.6 1 Myb_DNA-bind_5 Myb/SANT-like DNA-binding domain 0.0017 19.2 0.8 0.0017 19.2 0.8 1.7 2 Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain ------ inclusion threshold ------ 0.017 14.9 2.7 0.11 12.4 0.4 2.1 2 DUF1978 Domain of unknown function (DUF1978) 0.018 15.8 2.2 0.58 11.0 0.1 2.2 2 DUF641 Plant protein of unknown function (DUF641) 0.019 15.9 0.8 0.074 14.0 0.0 2.1 2 DUF4094 Domain of unknown function (DUF4094) 0.041 14.7 2.8 2.1 9.2 0.0 2.1 2 vRNAP_dom Virion DNA-directed RNA polymerase domain 0.07 13.8 0.1 0.16 12.6 0.1 1.5 1 SMBP Small metal-binding protein 0.17 12.7 0.5 0.46 11.3 0.5 1.7 1 MADF_DNA_bdg Alcohol dehydrogenase transcription factor My 0.18 11.7 0.7 0.31 11.0 0.7 1.5 1 Alginate_lyase Alginate lyase 0.49 11.4 3.6 3.1 8.9 0.6 2.4 2 Sulfatase_C C-terminal region of aryl-sulfatase 0.53 11.0 2.8 5.1 7.8 0.2 2.5 2 FYRC F/Y rich C-terminus 8.8 7.1 6.1 8.7 7.1 0.3 2.3 2 DUF948 Bacterial protein of unknown function (DUF948 Domain annotation for each model (and alignments): >> Myb_DNA-bind_5 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.8 2.8 1.1e-13 2.3e-10 23 76 .. 8 62 .. 6 64 .. 0.95 Alignments for each domain: == domain 1 score: 40.8 bits; conditional E-value: 1.1e-13 Myb_DNA-bind_5 23 ilenkksdaatwkaKnraWkeIaervnalgsv.eRtleelkkkwedlkrrtkrkl 76 +l +k+ +++t+++ + aW+eI+ +vna++++ ++t+e++ k+wed+ + +k+k FUN_002022-T1 8 VLKSKFCNSVTNNHNKTAWEEITVAVNAVNTGdQKTVEQVTKRWEDMTTSVKKKE 62 7999***************************99*******************985 PP >> Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.8 8e-07 0.0017 23 73 .. 12 65 .. 1 76 [. 0.75 2 ? -2.8 0.0 6 1.3e+04 64 73 .. 185 194 .. 173 210 .. 0.53 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 8e-07 Myb_DNA-bind_4 23 rfqe.kgkkrnkklweeiaekmaergy..krspeqckeKwenLkkkYkkekese 73 +f + ++ nk weei ++++ + +++ eq+ ++we+++ + kk + FUN_002022-T1 12 KFCNsVTNNHNKTAWEEITVAVNAVNTgdQKTVEQVTKRWEDMTTSVKKKETQA 65 44444456777789*********8755449***************999877664 PP == domain 2 score: -2.8 bits; conditional E-value: 6 Myb_DNA-bind_4 64 kkYkkekese 73 k+ kk+ ++ FUN_002022-T1 185 KSVKKVSQEL 194 3333333332 PP >> DUF1978 Domain of unknown function (DUF1978) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.4 4.9e-05 0.11 93 127 .. 40 74 .. 14 91 .. 0.89 2 ? 2.8 0.1 0.041 87 196 234 .. 171 210 .. 149 215 .. 0.81 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.9e-05 DUF1978 93 NqkeleeaekrllkalkdlkdqeierveeRlkele 127 qk +e+ +kr++++ + +k++e + +e +k l+ FUN_002022-T1 40 DQKTVEQVTKRWEDMTTSVKKKETQARQEEIKRLK 74 69*****************************9997 PP == domain 2 score: 2.8 bits; conditional E-value: 0.041 DUF1978 196 ks.eEleeqlesleellkessekLevlekhilklekeata 234 + +E + + le+ +k++s++L+ + +++ +++ + FUN_002022-T1 171 LAfQEKKRVIATLEKSVKKVSQELTARQAGFSRVTNSINK 210 4447778888999999999999999999999999888876 PP >> DUF641 Plant protein of unknown function (DUF641) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.4 0.025 54 81 111 .. 43 74 .. 7 89 .. 0.55 2 ? 11.0 0.1 0.00027 0.58 78 117 .. 172 211 .. 144 219 .. 0.85 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.025 DUF641 81 eqrsllktyeivvkkl.eselkakdseieeLr 111 + ++ k e + + ++e++a+++ei++L+ FUN_002022-T1 43 TVEQVTKRWEDMTTSVkKKETQARQEEIKRLK 74 23344444555544441568888889999887 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00027 DUF641 78 eiqeqrsllktyeivvkkleselkakdseieeLrekLeea 117 qe++++++t+e+ vkk+ +el+a+++ +++ ++++++ FUN_002022-T1 172 AFQEKKRVIATLEKSVKKVSQELTARQAGFSRVTNSINKN 211 5799***********************9999998888776 PP >> DUF4094 Domain of unknown function (DUF4094) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.3 0.96 2e+03 45 52 .. 52 61 .. 10 81 .. 0.51 2 ? 14.0 0.0 3.5e-05 0.074 23 89 .. 127 199 .. 117 200 .. 0.73 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.96 DUF4094 45 edcds..kkk 52 ed ++ kkk FUN_002022-T1 52 EDMTTsvKKK 61 2222222222 PP == domain 2 score: 14.0 bits; conditional E-value: 3.5e-05 DUF4094 23 lWtvpeskdiirrk.k..qelklvsedcds....kkkesrskdilgevsktheaiqtLdktissLemeLaaars 89 lW+++++ i++ + k + + v+e+c+s + + + + l ++++ +i tL+k++ ++ +eL+a ++ FUN_002022-T1 127 LWALENTARIPKYHgKnhTVRSCVEEKCESsffcGDLSKHPDEKLA-FQEKKRVIATLEKSVKKVSQELTARQA 199 68666666777777755455566999**988998444444434444.668999*****************8765 PP >> vRNAP_dom Virion DNA-directed RNA polymerase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.8 0.013 28 73 138 .. 12 74 .. 4 77 .. 0.83 2 ? 9.2 0.0 0.00099 2.1 94 142 .. 161 209 .. 139 211 .. 0.83 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.013 vRNAP_dom 73 kflknadlskldeealkelvkallekkkkeavtveeleeaieeleerlkesaesiearkkvlkkva 138 kf + + ++ +++a +e++ a+ ++ +++tve++++ e++++ +k++ + +ar++ +k+++ FUN_002022-T1 12 KFCNSVT-NNHNKTAWEEITVAVNAVNTGDQKTVEQVTKRWEDMTTSVKKK--ETQARQEEIKRLK 74 6677766.788899999999999999999999999999999*999999999..7888888887766 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00099 vRNAP_dom 94 allekkkkeavtveeleeaieeleerlkesaesiearkkvlkkvalsvD 142 l k+ e+++++e+++ i le+ +k+ +++ ar++ +++v s+ FUN_002022-T1 161 GDLSKHPDEKLAFQEKKRVIATLEKSVKKVSQELTARQAGFSRVTNSIN 209 5556667788899*********************************996 PP >> SMBP Small metal-binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.1 7.4e-05 0.16 21 72 .. 16 70 .. 4 77 .. 0.76 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.4e-05 SMBP 21 vvAeeHaaeAlehae...aavahgkaghaevLvehAeealkhakaaeevaegeek 72 v+++H + A e+ +av+ g++++ e++++ e + +k+ e +a++ee FUN_002022-T1 16 SVTNNHNKTAWEEITvavNAVNTGDQKTVEQVTKRWEDMTTSVKKKETQARQEEI 70 4678899999888651115667888999999999999*******99888887765 PP >> MADF_DNA_bdg Alcohol dehydrogenase transcription factor Myb/SANT-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.5 0.00022 0.46 25 68 .. 22 68 .. 12 79 .. 0.78 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00022 MADF_DNA_bdg 25 kekaweeiaeelgskvs.....veeckkkwknLRdqyrrelrkkksesg 68 + aweei +++++ + ve++ k+w+ + ++ +++ +++ ++ FUN_002022-T1 22 NKTAWEEITVAVNAVNTgdqktVEQVTKRWEDMTTSVKKKETQAR--QE 68 5679999999998666666666999*********99999888887..33 PP >> Alginate_lyase Alginate lyase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.7 0.00015 0.31 162 199 .. 18 54 .. 5 92 .. 0.80 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00015 Alginate_lyase 162 aaknNHgywaalqvaaialllgdrdlldkalkrykrai 199 + ++N ++w++++va a+ +gd++ ++++ kr ++ + FUN_002022-T1 18 TNNHNKTAWEEITVAVNAVNTGDQKTVEQVTKR-WEDM 54 33466689***********************88.5555 PP >> Sulfatase_C C-terminal region of aryl-sulfatase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.1 2.2e+02 78 107 .. 40 69 .. 25 82 .. 0.81 2 ? 8.9 0.6 0.0014 3.1 60 118 .. 162 216 .. 135 223 .. 0.84 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.1 Sulfatase_C 78 ykevlkeikkaveehkatlkpvpsqlskgn 107 ++ +++++k +e++ ++k+ ++q + + FUN_002022-T1 40 DQKTVEQVTKRWEDMTTSVKKKETQARQEE 69 5788999************99999987764 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0014 Sulfatase_C 60 dlerDpsEkyplspespeykevlkeikkaveehkatlkpvpsqlskgnllvkpwlqpcC 118 dl++ p Ek + e k v+++++k v+++ ++l+ + +s+++++ ++ ++ C FUN_002022-T1 162 DLSKHPDEKLAFQ----EKKRVIATLEKSVKKVSQELTARQAGFSRVTNSINKNIAMDC 216 8899999999998....678999***************999999999888877666666 PP >> FYRC F/Y rich C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.2 0.0024 5.1 2 39 .. 3 40 .. 2 48 .. 0.86 2 ? 3.1 0.4 0.072 1.5e+02 20 52 .. 46 77 .. 41 80 .. 0.75 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0024 FYRC 2 PlFrvtveedpdlkfegssptkcWeevlervnelrkea 39 P ++v+++++ ++++++ + +Wee++ +vn + FUN_002022-T1 3 PILEVVLKSKFCNSVTNNHNKTAWEEITVAVNAVNTGD 40 8999****************************965544 PP == domain 2 score: 3.1 bits; conditional E-value: 0.072 FYRC 20 sptkcWeevlervnelrkeaglklklfpesisG 52 +tk We+ + +v++++ +a+++ ++++ +++G FUN_002022-T1 46 QVTKRWEDMTTSVKKKETQARQE-EIKRLKVTG 77 57899**********99888886.444444444 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 1.2 0.14 3e+02 33 51 .. 42 60 .. 15 75 .. 0.55 2 ? 7.1 0.3 0.0041 8.7 28 66 .. 173 211 .. 169 214 .. 0.86 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.14 DUF948 33 ktleklekqldpllkette 51 kt+e+++k+ +++++ +++ FUN_002022-T1 42 KTVEQVTKRWEDMTTSVKK 60 3333333333333333322 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0041 DUF948 28 ldevnktleklekqldpllkettellaktnelledvnek 66 ++e ++++++lek ++++++e+t+ a ++++ +n+ FUN_002022-T1 173 FQEKKRVIATLEKSVKKVSQELTARQAGFSRVTNSINKN 211 67888999**************99999999999988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (233 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2311 (0.0904678); expected 510.9 (0.02) Passed bias filter: 1075 (0.0420826); expected 510.9 (0.02) Passed Vit filter: 108 (0.00422783); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.32u 0.42s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 2278.38 // Query: FUN_002023-T1 [L=130] Description: FUN_002023 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.6e-06 27.3 0.1 6.7e-06 26.5 0.1 1.4 1 rva_4 Integrase core domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.1 2.6e-10 6.7e-06 1 24 [. 94 117 .. 94 120 .. 0.93 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 2.6e-10 rva_4 1 vykvatPnslWhidgnmklirWrl 24 vy+v P slWh+dgn+kl+r+ l FUN_002023-T1 94 VYNVRSPLSLWHMDGNHKLVRFIL 117 8********************865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 869 (0.0340184); expected 510.9 (0.02) Passed bias filter: 733 (0.0286945); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1335.43 // Query: FUN_002024-T1 [L=340] Description: FUN_002024 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.8e-09 35.7 0.5 8.8e-08 32.6 0.1 2.0 2 HECT HECT-domain (ubiquitin-transferase) Domain annotation for each model (and alignments): >> HECT HECT-domain (ubiquitin-transferase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.013 3.3e+02 10 73 .. 111 171 .. 102 194 .. 0.78 2 ! 32.6 0.1 3.4e-12 8.8e-08 211 282 .. 236 311 .. 214 324 .. 0.79 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.013 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 10 pelglfeeeseeskllwfnpesseeeklelfkllGkllGkaiyegllldlpfpraflkkllgke 73 + lf+e+ ++ ++l+ ++ s e+++ ++ G ++G ++++g +l+ +++ ++ ++ k+ FUN_002024-T1 111 IRDRLFKEQGATGHILQETEASLEKNS---YYGNGLFFGFSLLQGGPLPNFLSEEQIQRIFTKD 171 455799888888888888888777667...9*************99999999988888888754 PP == domain 2 score: 32.6 bits; conditional E-value: 3.4e-12 xxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 211 tkeskvikwfweileefseeerr.......klLkFvTgssrlPlgGfkslpkltIqkksgkdddrLPtahTCfnlLklp 282 ++e+++ ++f+++l+e+s +r+ + LkFvTg+ P+ Gfk p+++ + + ++ +P ++TC+n+L lp FUN_002024-T1 236 QQEERTYRLFLSYLKEVSAARRAngnisleDVLKFVTGCNYEPVLGFKMKPSICFDT---NMPSCIPISNTCINTLTLP 311 67888999999999999888875333333379****************435555555...5799**************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (340 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 571 (0.0223527); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3357.28 // Query: FUN_002025-T1 [L=603] Description: FUN_002025 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.058 14.3 0.3 0.058 14.3 0.3 3.3 4 Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain 0.13 12.9 0.0 0.45 11.2 0.0 1.9 1 Frataxin_Cyay Frataxin-like domain 1.7 9.5 14.2 2.6 9.0 3.3 3.2 2 HIP1_clath_bdg Clathrin-binding domain of Huntingtin-interac 1.9 9.1 18.8 0.1 13.3 8.8 2.6 2 ATG16 Autophagy protein 16 (ATG16) 2.3 9.2 6.2 22 6.0 0.2 4.1 4 FlaC_arch Flagella accessory protein C (FlaC) Domain annotation for each model (and alignments): >> Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.1 0.38 2e+03 47 67 .. 207 226 .. 168 250 .. 0.68 2 ? -0.4 0.6 0.43 2.2e+03 28 44 .. 236 252 .. 205 287 .. 0.57 3 ? 14.3 0.3 1.1e-05 0.058 33 87 .. 281 337 .. 264 339 .. 0.73 4 ? -1.3 0.1 0.86 4.4e+03 15 44 .. 498 525 .. 486 531 .. 0.75 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.38 Myb_DNA-bind_4 47 gykrspeqckeKwenLkkkYk 67 + rsp+ +++ +++Lk Yk FUN_002025-T1 207 KWSRSPTMVQSIIDSLKE-YK 226 456899999999999875.44 PP == domain 2 score: -0.4 bits; conditional E-value: 0.43 Myb_DNA-bind_4 28 gkkrnkklweeiaekma 44 + + kl+e++ + ma FUN_002025-T1 236 FNADKVKLYEKVRQMMA 252 23333345555544444 PP == domain 3 score: 14.3 bits; conditional E-value: 1.1e-05 Myb_DNA-bind_4 33 kklweei...aekmaergykrspeqckeKwenLkkkYkkekesekgsgs...kwpyfeeld 87 k ++++ +++m ++gy +keK++n++++Y k+ s+++sgs +++++l FUN_002025-T1 281 YKAYKAVydkEAEMIRKGY----NRIKEKVKNIRQDYSKAVVSGTRSGSgkiVIEHYDDLA 337 4455555111345777788....78****************99888886557788998886 PP == domain 4 score: -1.3 bits; conditional E-value: 0.86 Myb_DNA-bind_4 15 iwkellelrfqekgkkrnkklweeiaekma 44 ++ke +++ f+e ++ +k e++++ m+ FUN_002025-T1 498 LRKEMMDC-FRE-STATTAKAMEQMSQTMK 525 46665566.777.77778888899999887 PP >> Frataxin_Cyay Frataxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 8.8e-05 0.45 4 79 .. 282 355 .. 278 370 .. 0.89 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 8.8e-05 Frataxin_Cyay 4 eefhkladetlesleekleeladeaeedaldveyssgvLtlefenggtyvinkqepnkqIWlsspisgpkrfdyde 79 ++++++ d+ e + + +++++++ +++ +ys+ v++ + + +g++vi + IW sp + p f +d+ FUN_002025-T1 282 KAYKAVYDKEAEMIRKGYNRIKEKV-KNI-RQDYSKAVVSGTRSGSGKIVIEHYDDLATIWGGSPSTEPLAFGVDS 355 579999******************7.555.89*********************************99999998776 PP >> HIP1_clath_bdg Clathrin-binding domain of Huntingtin-interacting protein 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 3.3 0.0005 2.6 47 91 .. 73 117 .. 42 129 .. 0.86 2 ? 5.2 2.7 0.0074 38 11 92 .. 475 527 .. 441 552 .. 0.61 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0005 HIP1_clath_bdg 47 leeQkeelekLkreLessraELaklkssLesseqsgeelssqlaa 91 ++ k+el++Lk L+ s EL + k+ L+++++++ +l+++l+a FUN_002025-T1 73 NKQFKKELDELKPSLQLSDIELRNTKTKLDEAAKANIKLEKRLHA 117 4566899****************************9999998864 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0074 HIP1_clath_bdg 11 vtkqltvarqaqeeverekkeleeelervkeeaerkleeQkeelekLkreLessraELaklkssLesseqsgeelssqlaaL 92 + k lt+a+ q+ + e+ k++ + +++ ++ +++s ++++++ e++s+++++L FUN_002025-T1 475 LEKRLTAAQRDQKLL-----------------------------EAAKEDACLRKEMMDCFRESTATTAKAMEQMSQTMKGL 527 334455555555555.............................55555555555555555555555555555555555554 PP >> ATG16 Autophagy protein 16 (ATG16) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 8.8 2e-05 0.1 44 163 .. 22 139 .. 12 142 .. 0.81 2 ? 0.5 2.3 0.16 8.1e+02 70 127 .. 459 490 .. 397 532 .. 0.54 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2e-05 ATG16 44 eaasatpsssqstsskkskkekeasassqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlaeleaeraqleekl 139 +aa+ ++ +++++ ++k+ +++s+++++ ++++ ++ l+ ++ l+ +r++++++++l el+ +lq + +lr+ + +l+e+ + + +le++l FUN_002025-T1 22 SAAKRHNMADNGAV--ETKNDDTSSSEQNEPDLHEIKAMLVDIQISLSFILRENKQFKKELDELKPSLQLSDIELRNTKTKLDEAAKANIKLEKRL 115 33333333333333..3455555555557899**************************************************************** PP ATG16 140 kdreeelrekaklvedlqDElvaL 163 r+ l+ ++ + + +E++ L FUN_002025-T1 116 HARTTSLESARNDLREHTEEINYL 139 *********999999999998776 PP == domain 2 score: 0.5 bits; conditional E-value: 0.16 ATG16 70 ssqsakiqsleqklaqlreelaeaqrsrgelaqrllelneelqelekklrederrlae 127 ++ s+ + ++k+ +l++ l++aqr ++ l e FUN_002025-T1 459 EAVSNVPKLIDNKRKHLEKRLTAAQRDQKLL--------------------------E 490 1112222223444444444444444444332..........................2 PP >> FlaC_arch Flagella accessory protein C (FlaC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.2 0.0044 22 4 36 .. 54 86 .. 52 89 .. 0.88 2 ? 0.6 0.1 0.22 1.1e+03 5 30 .. 111 136 .. 93 142 .. 0.70 3 ? 2.2 0.1 0.07 3.6e+02 21 39 .. 290 308 .. 286 315 .. 0.68 4 ? -2.5 0.0 2 1e+04 18 37 .. 512 531 .. 503 537 .. 0.72 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0044 FlaC_arch 4 elEnklekleseletlrkeneeisksveeieen 36 e+ l +++++l+ + +en++ +k+++e++ + FUN_002025-T1 54 EIKAMLVDIQISLSFILRENKQFKKELDELKPS 86 788889999********************9865 PP == domain 2 score: 0.6 bits; conditional E-value: 0.22 FlaC_arch 5 lEnklekleseletlrkeneeisksv 30 lE++l ++le++r+ + e +++ FUN_002025-T1 111 LEKRLHARTTSLESARNDLREHTEEI 136 66666666666666665554444444 PP == domain 3 score: 2.2 bits; conditional E-value: 0.07 FlaC_arch 21 keneeisksveeieenvkk 39 ke e+i+k ++i+e+vk+ FUN_002025-T1 290 KEAEMIRKGYNRIKEKVKN 308 5667777777777777665 PP == domain 4 score: -2.5 bits; conditional E-value: 2 FlaC_arch 18 tlrkeneeisksveeieenv 37 t k +e+ s++ + + e + FUN_002025-T1 512 TTAKAMEQMSQTMKGLSEGI 531 55677888888888777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (603 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2085 (0.0816207); expected 510.9 (0.02) Passed bias filter: 702 (0.0274809); expected 510.9 (0.02) Passed Vit filter: 78 (0.00305344); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 5880.19 // Query: FUN_002026-T1 [L=431] Description: FUN_002026 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (431 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 793 (0.0310433); expected 510.9 (0.02) Passed bias filter: 484 (0.018947); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 4225.73 // Query: FUN_002027-T1 [L=197] Description: FUN_002027 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0061 16.6 0.1 0.011 15.7 0.1 1.4 1 HopBF1_kinase Type III secretion system effector HopBF1 kina ------ inclusion threshold ------ 0.11 11.4 0.0 0.12 11.3 0.0 1.1 1 DUF7481 Family of unknown function (DUF7481) Domain annotation for each model (and alignments): >> HopBF1_kinase Type III secretion system effector HopBF1 kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.1 9e-07 0.011 92 133 .. 4 45 .. 1 54 [. 0.89 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 9e-07 HopBF1_kinase 92 rpavvmdrfAqgSkdiVklengkvrivgdssllNkksiedln 133 ++ v +d+ A g kd+V ++++k+r +++ l ++si+++ FUN_002027-T1 4 KACVDFDKLATGWKDVVVTREKKIRLLEEVLNLHSESISEID 45 667889********************************9986 PP >> DUF7481 Family of unknown function (DUF7481) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 9.6e-06 0.12 51 104 .. 50 102 .. 31 156 .. 0.81 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 9.6e-06 DUF7481 51 lCeertysdGaryCtPriseavytnelCekavGvgt..gleaPkyfatyyeldgks 104 +C++ ++s Ga P seavy+ C++++ + e +f + y+l+g+ FUN_002027-T1 50 VCKI-DFSKGAVLNCPNSSEAVYI--SCKQMLPESAvdLYEDTDFFSALYTLKGEM 102 5655.69****************9..599*997654114678899******99994 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (197 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 646 (0.0252887); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1982.01 // Query: FUN_002028-T1 [L=178] Description: FUN_002028 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-12 45.5 0.1 5.7e-12 45.5 0.1 1.0 1 DUF6589 Family of unknown function (DUF6589) ------ inclusion threshold ------ 0.047 13.9 0.1 0.06 13.6 0.1 1.1 1 DUF3431 Protein of unknown function (DUF3431) 0.51 11.2 1.0 5.9 7.8 0.3 2.2 2 KASH Nuclear envelope localisation domain Domain annotation for each model (and alignments): >> DUF6589 Family of unknown function (DUF6589) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.5 0.1 6.7e-16 5.7e-12 105 218 .. 26 139 .. 1 162 [. 0.83 Alignments for each domain: == domain 1 score: 45.5 bits; conditional E-value: 6.7e-16 DUF6589 105 rlilvgGDqlTverlrslkkyraeddnsferldwllpipglfHlkmaalsaifethwgspnsrdpssLghhatlLgrkpisnlkkp...dfhtlre 197 + +++ GDqlT er r + ++ e l+ + p ++ +Hlk +l+ if++ + +++s +g +++ ++rk++sn kk d+++ ++ FUN_002028-T1 26 QKMFFDGDQLTEERARNCQWANNLASTLTECLEGITPAFADWHLKKMFLR-IFRQLFFKESSAA--EMGTSCASMNRKAKSNAKKGpeeDYNAYKD 118 45899**************999988888899**************77775.9999998888844..47777999****666655555********* PP DUF6589 198 lifhvlearvldcwllvlgkd 218 +i ea++ + w++++g + FUN_002028-T1 119 FIDRETEAHIVSRWMVFAGMT 139 ***************998865 PP >> DUF3431 Protein of unknown function (DUF3431) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 7e-06 0.06 105 186 .. 50 125 .. 23 136 .. 0.74 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 7e-06 DUF3431 105 ckwepgCpaelkplpeeeeeeekkeeealaeafeelfpeeevpevvaapCCaqFavsrerirkrpreeYvrlrdwlleteld 186 ++ ++C + ++p+ ++ + ++++ ++f++lf +e+ +++++C++ ++++ +k p e+Y +++d++ + + + FUN_002028-T1 50 ASTLTECLEGITPA-----FADWHLKKMFLRIFRQLFFKESSAAEMGTSCASMNRKAKSNAKKGPEEDYNAYKDFIDRET-E 125 33333444444433.....34567778999*******99999********************************986533.3 PP >> KASH Nuclear envelope localisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.3 0.00069 5.9 30 49 .. 38 57 .. 34 58 .. 0.83 2 ? 1.6 0.0 0.057 4.8e+02 27 44 .. 86 103 .. 67 105 .. 0.82 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.00069 KASH 30 eednsCtlaNnfarSfkpmL 49 e + C+ aNn+a++++ L FUN_002028-T1 38 ERARNCQWANNLASTLTECL 57 56789**********98766 PP == domain 2 score: 1.6 bits; conditional E-value: 0.057 KASH 27 PaseednsCtlaNnfarS 44 +a e ++sC++ N+ a+S FUN_002028-T1 86 SAAEMGTSCASMNRKAKS 103 5678899******98877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 661 (0.0258759); expected 510.9 (0.02) Passed bias filter: 561 (0.0219612); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1830.47 // Query: FUN_002029-T1 [L=377] Description: FUN_002029 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (377 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1016 (0.0397729); expected 510.9 (0.02) Passed bias filter: 541 (0.0211783); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.38s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3707.70 // Query: FUN_002030-T1 [L=113] Description: FUN_002030 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.7 0.0 0.23 12.1 0.0 1.5 1 RA_2 RA like domain Domain annotation for each model (and alignments): >> RA_2 RA like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 8.9e-06 0.23 4 35 .. 37 68 .. 34 95 .. 0.90 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 8.9e-06 RA_2 4 vvkvflmDgsskavevdsattarevceklaek 35 ++k++ g++k ve++ +t++ +ce l++ FUN_002030-T1 37 TLKILNDSGRVKDVEFSNNATSQHICELLSNS 68 7899999********************99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (113 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 682 (0.026698); expected 510.9 (0.02) Passed bias filter: 467 (0.0182815); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1152.85 // Query: FUN_002031-T1 [L=333] Description: FUN_002031 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.2e-08 32.6 4.9 7.2e-08 32.6 4.9 3.1 3 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 2.4e-05 24.5 3.8 2.4e-05 24.5 3.8 3.6 4 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) 3.4e-05 24.2 4.2 3.4e-05 24.2 4.2 3.4 1 zf-RING_5 zinc-RING finger domain 0.00016 22.1 5.4 0.00016 22.1 5.4 3.3 4 zf-RING_UBOX RING-type zinc-finger 0.00016 21.9 7.6 0.00016 21.9 7.6 3.3 3 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 0.00026 22.1 20.7 0.0028 18.8 5.8 3.6 3 zf-TRAF TRAF-type zinc finger 0.00035 21.3 5.2 0.00035 21.3 5.2 4.2 4 zf-RING_2 Ring finger domain ------ inclusion threshold ------ 0.017 15.4 1.3 0.017 15.4 1.3 3.0 2 zf-RING_4 RING/Ubox like zinc-binding domain 0.15 12.2 8.0 0.27 11.4 0.0 3.2 3 RNF220 E3 ubiquitin-protein ligase RNF220 0.26 11.8 2.8 2.3 8.8 0.3 2.6 3 ParE_like ParE-like toxin domain 7.3 7.1 17.0 0.25 11.8 6.2 3.6 3 Prok-RING_4 Prokaryotic RING finger family 4 Domain annotation for each model (and alignments): >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.6 4.9 3.1e-11 7.2e-08 1 40 [] 26 66 .. 26 66 .. 0.94 2 ? -0.4 0.2 0.66 1.5e+03 1 10 [. 90 99 .. 88 110 .. 0.64 3 ? -2.0 0.4 2.1 4.9e+03 24 38 .. 148 163 .. 139 164 .. 0.50 Alignments for each domain: == domain 1 score: 32.6 bits; conditional E-value: 3.1e-11 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCikslle.snnvkCplC 40 C +C++ + + +++pCgHsfC +C+++l + ++ Cp+C FUN_002031-T1 26 CDVCIKPVVLAQMATPCGHSFCGFCVEELGKtGGPISCPMC 66 9**********9*******************777777**** PP == domain 2 score: -0.4 bits; conditional E-value: 0.66 zf-C3HC4 1 CpiCleelke 10 C+ C e++k+ FUN_002031-T1 90 CSHCAEKVKR 99 5555555554 PP == domain 3 score: -2.0 bits; conditional E-value: 2.1 zf-C3HC4 24 sCikslle.snnvkCp 38 + i+ +l s + +Cp FUN_002031-T1 148 DMIERYLLpSHTLQCP 163 3333333344445555 PP >> zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 3.8 1e-08 2.4e-05 2 47 .. 23 71 .. 22 73 .. 0.87 2 ? 1.3 3.9 0.18 4.3e+02 24 39 .. 88 109 .. 77 118 .. 0.80 3 ? -1.2 0.5 1.1 2.5e+03 35 48 .. 138 152 .. 132 153 .. 0.71 4 ? -2.9 0.3 3.8 8.7e+03 28 41 .. 161 171 .. 158 179 .. 0.66 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1e-08 zf-C3HC4_3 2 eeeCviClerernv.vllpCgHlclCeeCaeklr...kkkkCpiCrqkie 47 e +C +C + + + + +pCgH +C C e+l +Cp+Crq + FUN_002031-T1 23 EFMCDVCIKPVVLAqMATPCGHS-FCGFCVEELGktgGPISCPMCRQRVG 71 568999999977653788*****.*********9999999*******985 PP == domain 2 score: 1.3 bits; conditional E-value: 0.18 zf-C3HC4_3 24 clCeeCaeklr......kkkkC 39 ++C++Caek++ ++++C FUN_002031-T1 88 MVCSHCAEKVKrgdtsfHSDRC 109 5899999999876666666666 PP == domain 3 score: -1.2 bits; conditional E-value: 1.1 zf-C3HC4_3 35 kkkkCpi.Crqkies 48 kk +Cp+ C+ ie+ FUN_002031-T1 138 KKISCPLnCKDMIER 152 568999889888875 PP == domain 4 score: -2.9 bits; conditional E-value: 3.8 zf-C3HC4_3 28 eCaeklrkkkkCpi 41 +C l + Cpi FUN_002031-T1 161 QCPAAL---TLCPI 171 566666...77887 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 4.2 1.5e-08 3.4e-05 2 43 .] 26 68 .. 25 68 .. 0.91 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 1.5e-08 zf-RING_5 2 CnkCfkelsktrkfyltsCgHifCeeClkkll...eerqCpiCkk 43 C +C k++ + t+CgH+fC C+ +l + +Cp+C++ FUN_002031-T1 26 CDVCIKPV--VLAQMATPCGHSFCGFCVEELGktgGPISCPMCRQ 68 88888888..788899***************************96 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 5.4 6.8e-08 0.00016 1 39 [] 26 64 .. 26 64 .. 0.91 2 ? -1.1 0.4 1.2 2.8e+03 13 24 .. 89 93 .. 74 104 .. 0.64 3 ? -2.0 0.8 2.3 5.4e+03 27 39 .] 131 143 .. 115 143 .. 0.68 4 ? -1.7 0.1 1.9 4.4e+03 21 39 .] 146 163 .. 146 163 .. 0.77 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 6.8e-08 zf-RING_UBOX 1 CpICleeftdP.lvlpCGHtfCreClwelskkekgkikCP 39 C +C ++ + +pCGH+fC C+ e +k +g i+CP FUN_002031-T1 26 CDVCIKPVVLAqMATPCGHSFCGFCV-EELGKTGGPISCP 64 9999999996655689**********.89**********9 PP == domain 2 score: -1.1 bits; conditional E-value: 1.2 zf-RING_UBOX 13 vlpCGHtfCreC 24 v C H C FUN_002031-T1 89 V--CSH-----C 93 3..555.....4 PP == domain 3 score: -2.0 bits; conditional E-value: 2.3 zf-RING_UBOX 27 elskkekgkikCP 39 + ++ + +ki+CP FUN_002031-T1 131 KEDSCSWKKISCP 143 5566677889998 PP == domain 4 score: -1.7 bits; conditional E-value: 1.9 zf-RING_UBOX 21 CreClwelskkekgkikCP 39 C++ + e + +++++CP FUN_002031-T1 146 CKDMI-ERYLLPSHTLQCP 163 77777.6777888999999 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 7.6 6.9e-08 0.00016 1 40 [] 25 66 .. 25 66 .. 0.89 2 ? -2.5 0.6 2.9 6.8e+03 22 27 .. 89 94 .. 73 102 .. 0.69 3 ? -0.4 0.5 0.62 1.4e+03 5 30 .. 146 153 .. 141 164 .. 0.46 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 6.9e-08 zf-C3HC4_2 1 eCpiCldmlkdplvvtpCgHvfCqkCilraLeesn..eCPlC 40 +C +C+ + + tpCgH+fC C+ + + + +CP+C FUN_002031-T1 25 MCDVCIKPVVLAQMATPCGHSFCGFCVEELGKTGGpiSCPMC 66 7******999999**************9965555569****9 PP == domain 2 score: -2.5 bits; conditional E-value: 2.9 zf-C3HC4_2 22 fCqkCi 27 C++C FUN_002031-T1 89 VCSHCA 94 355554 PP == domain 3 score: -0.4 bits; conditional E-value: 0.62 zf-C3HC4_2 5 CldmlkdplvvtpCgHvfCqkCilra 30 C+dm++ r+ FUN_002031-T1 146 CKDMIE------------------RY 153 555555..................32 PP >> zf-TRAF TRAF-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 2.4 1.8 4.2e+03 38 55 .. 87 100 .. 60 105 .. 0.70 2 ! 18.8 5.8 1.2e-06 0.0028 1 60 [] 105 158 .. 105 158 .. 0.92 3 ! 13.2 0.3 6.6e-05 0.15 1 32 [. 158 189 .. 158 194 .. 0.92 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 1.8 zf-TRAF 38 evkCkfkevGCkekvkre 55 ++ C++ C+ekvkr FUN_002031-T1 87 KMVCSH----CAEKVKRG 100 455666....77776664 PP == domain 2 score: 18.8 bits; conditional E-value: 1.2e-06 zf-TRAF 1 HletCpfapvpCpnecckkkilRedlkdHlekdCkkaevkCkfkevGCkekvkrealqkH 60 H C + v C c+ + ++d+++H e++C+ ++ C+ Ck +++r l +H FUN_002031-T1 105 HSDRCVMKDVHC--VCGIR-LKQKDIDAHKEDSCSWKKISCPL---NCKDMIERYLLPSH 158 9999********..68876.**********************9...8****999888777 PP == domain 3 score: 13.2 bits; conditional E-value: 6.6e-05 zf-TRAF 1 HletCpfapvpCpnecckkkilRedlkdHlek 32 H +Cp a Cp + c + + R d+++H+e+ FUN_002031-T1 158 HTLQCPAALTLCPIKGCGTHLRRGDVEKHIEA 189 8889*********9999999**********95 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 5.2 1.5e-07 0.00035 2 44 .] 25 67 .. 24 67 .. 0.84 2 ? -1.4 3.4 1.8 4.1e+03 21 40 .. 74 93 .. 69 109 .. 0.69 3 ? -1.3 1.3 1.7 4e+03 20 41 .. 141 163 .. 128 164 .. 0.62 4 ? -1.5 0.0 1.9 4.5e+03 19 27 .. 243 251 .. 234 257 .. 0.75 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 1.5e-07 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst..CPlCr 44 +C +C +++ + ++ pCgH f+ C++++ +t CP+Cr FUN_002031-T1 25 MCDVCIKPVVLAQMAT--PCGHSFCGFCVEELGKTGGPisCPMCR 67 6999*98887766655..9************777766699****9 PP == domain 2 score: -1.4 bits; conditional E-value: 1.8 zf-RING_2 21 CgHvfhkeCldkwlrtsstC 40 C+ +f ++ l++w s+C FUN_002031-T1 74 CKNIFACKALSTWKMVCSHC 93 66666666666665555555 PP == domain 3 score: -1.3 bits; conditional E-value: 1.7 zf-RING_2 20 pCgHvfhkeCldkwlrtsst..CP 41 C +k+ ++++l s+t CP FUN_002031-T1 141 SC-PLNCKDMIERYLLPSHTlqCP 163 35.345667777777777777777 PP == domain 4 score: -1.5 bits; conditional E-value: 1.9 zf-RING_2 19 lpCgHvfhk 27 + C+ vfhk FUN_002031-T1 243 TTCSPVFHK 251 459999997 PP >> zf-RING_4 RING/Ubox like zinc-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 1.3 7.4e-06 0.017 19 45 .. 41 68 .. 35 70 .. 0.86 2 ? -0.1 0.3 0.5 1.2e+03 1 13 [. 90 102 .. 75 111 .. 0.66 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 7.4e-06 zf-RING_4 19 eCgyqiClfCyedilee.eegrCPgCre 45 +Cg+ +C fC e++ ++ CP Cr+ FUN_002031-T1 41 PCGHSFCGFCVEELGKTgGPISCPMCRQ 68 7*************98624578*****8 PP == domain 2 score: -0.1 bits; conditional E-value: 0.5 zf-RING_4 1 cplCdekldetdk 13 c C+ek+ d+ FUN_002031-T1 90 CSHCAEKVKRGDT 102 4444444444444 PP >> RNF220 E3 ubiquitin-protein ligase RNF220 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.6 0.2 4.3 1e+04 5 12 .. 60 67 .. 58 71 .. 0.74 2 ? 2.3 2.4 0.07 1.6e+02 110 139 .. 89 127 .. 83 136 .. 0.67 3 ? 11.4 0.0 0.00012 0.27 6 42 .. 167 218 .. 163 258 .. 0.72 Alignments for each domain: == domain 1 score: -3.6 bits; conditional E-value: 4.3 RNF220 5 plcCPiCg 12 p +CP+C FUN_002031-T1 60 PISCPMCR 67 77888885 PP == domain 2 score: 2.3 bits; conditional E-value: 0.07 RNF220 110 vcpvCnkkvs.eeitlhvdaclrkse........naade 139 vc C +kv+ + + h d+c+ k+ +++d FUN_002031-T1 89 VCSHCAEKVKrGDTSFHSDRCVMKDVhcvcgirlKQKDI 127 788899998877888999999888766666555433333 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00012 RNF220 6 lcCPi..CgvtlrpqEleqHfakEldrLtkllkskrdl.............s 42 + CPi Cg lr +++e+H++ + r ++llk r+ s FUN_002031-T1 167 TLCPIkgCGTHLRRGDVEKHIEANQPRHYRLLKEDRNDilwrvkemplfrlS 218 67***99**************************9998777777777766332 PP >> ParE_like ParE-like toxin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 8.1 1.9e+04 43 51 .. 86 94 .. 84 97 .. 0.72 2 ? 2.3 0.1 0.1 2.4e+02 41 53 .. 193 205 .. 177 210 .. 0.84 3 ? 8.8 0.3 0.001 2.3 40 53 .. 253 266 .. 251 271 .. 0.87 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 8.1 ParE_like 43 yRLLsrdeg 51 + +++ + FUN_002031-T1 86 WKMVCSHCA 94 888888776 PP == domain 2 score: 2.3 bits; conditional E-value: 0.1 ParE_like 41 rryRLLsrdegkt 53 r+yRLL +d + FUN_002031-T1 193 RHYRLLKEDRNDI 205 89*****998765 PP == domain 3 score: 8.8 bits; conditional E-value: 0.001 ParE_like 40 grryRLLsrdegkt 53 grr+RLL+ + g++ FUN_002031-T1 253 GRRWRLLCTKRGER 266 89********9988 PP >> Prok-RING_4 Prokaryotic RING finger family 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 6.2 0.00011 0.25 12 41 .. 38 71 .. 26 75 .. 0.76 2 ? 1.1 0.1 0.24 5.5e+02 19 28 .. 88 97 .. 83 100 .. 0.83 3 ? -2.4 0.5 2.8 6.4e+03 32 38 .. 141 148 .. 134 152 .. 0.64 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.00011 Prok-RING_4 12 vlspCgHlvCkeCfdssdfs....aCPiCrrrvd 41 + pCgH C C ++ +CP+Cr+rv FUN_002031-T1 38 MATPCGHSFCGFCVEELGKTggpiSCPMCRQRVG 71 568***********98665533557*******85 PP == domain 2 score: 1.1 bits; conditional E-value: 0.24 Prok-RING_4 19 lvCkeCfdss 28 +vC +C +++ FUN_002031-T1 88 MVCSHCAEKV 97 8*****8765 PP == domain 3 score: -2.4 bits; conditional E-value: 2.8 Prok-RING_4 32 aCPi.Crr 38 +CP+ C+ FUN_002031-T1 141 SCPLnCKD 148 59985664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (333 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1217 (0.0476414); expected 510.9 (0.02) Passed bias filter: 566 (0.022157); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 3285.39 // Query: FUN_002032-T1 [L=290] Description: FUN_002032 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 9.2 6.2 13.8 12 5.8 13.8 1.1 1 MIIP Migration and invasion-inhibitory Domain annotation for each model (and alignments): >> MIIP Migration and invasion-inhibitory # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 13.8 0.00048 12 20 143 .. 34 160 .. 20 183 .. 0.76 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.00048 MIIP 20 avrrsvakaasessldssssedsetplsqetssassrasssq.da..rqadpcdvaskgsassrvaslppakaqhqeslglprprsapllatsdlk 112 + r ++a+a+ ++ ++++++ed + + +++ ++++r s ++ r++ + + k+++ + +++++ + + +++ +++++ + + + t++ + FUN_002032-T1 34 RERDAIAEASEKKGQEKATAEDIRNRALERMGQTKKRKSEDGqEPksRRSSNAALQFKQEKAESDKAFREEELKIRKKEEETKAPQFQAMFTQQQS 129 4466789999999999999***99999999988887776543244446777777777777777779************999999999999899999 PP MIIP 113 dpepsaelddlgnqeaqalrsilarqskqsk 143 + +++++ + +q++q ++ ++a+qs+ FUN_002032-T1 130 FLQAMTQQQAQQQQQNQHMQMLMAQQSQAMM 160 9999999999999999999999988887543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (290 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 4946 (0.193619); expected 510.9 (0.02) Passed bias filter: 883 (0.0345665); expected 510.9 (0.02) Passed Vit filter: 125 (0.00489333); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.39u 0.40s 00:00:00.79 Elapsed: 00:00:00.42 # Mc/sec: 2795.64 // Query: FUN_002033-T1 [L=467] Description: FUN_002033 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-10 41.4 0.0 4.8e-10 39.8 0.0 1.9 2 DDE_Tnp_4 DDE superfamily endonuclease 3.6e-05 24.9 0.6 9.2e-05 23.6 0.4 1.8 1 THAP THAP domain ------ inclusion threshold ------ 0.077 13.2 0.0 0.43 10.8 0.0 2.2 1 DDE_Tnp_1 Transposase DDE domain 0.11 13.1 1.4 0.24 11.9 1.4 1.5 1 DUF1664 Protein of unknown function (DUF1664) 0.17 12.3 0.3 0.32 11.4 0.3 1.4 1 DUF7590 Domain of unknown function (DUF7590) 4.3 7.7 8.9 0.63 10.5 2.5 2.1 2 Phage_scaffold Phage capsid assembly scaffolding protein Domain annotation for each model (and alignments): >> DDE_Tnp_4 DDE superfamily endonuclease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.1 1.2 5.1e+03 100 116 .. 150 165 .. 118 184 .. 0.47 2 ! 39.8 0.0 1.1e-13 4.8e-10 56 157 .. 345 447 .. 336 448 .. 0.87 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 1.2 DDE_Tnp_4 100 kqlseeevefnrriasa 116 ++l + + + + i+++ FUN_002033-T1 150 ENL-SLQSQNTSLISEN 165 222.2223333333333 PP == domain 2 score: 39.8 bits; conditional E-value: 1.1e-13 DDE_Tnp_4 56 ksilensgllkaleeavlpgdvilaDkgFplsdkllvpakk........kkkkqlseeevefnrriasarihvErvigrlkgrFrilqkrlpisli 143 +i+e+ +++++ +g+v+l+DkgF +sd l+ +k+ k ++q +e++ n ia++ri E++igr++ ++il+k+ p+ ++ FUN_002033-T1 345 EQITEQIDVIDYCP----KGKVVLTDKGFAISD--LCHEKGvnhnrppmKFNTQYDENDISLNFDIATLRIYNENAIGRIR-DWSILNKYWPSGRV 433 67999999999955....99*************..9888889999999999******************************.******99998877 PP DDE_Tnp_4 144 ekldkivtvccvLh 157 + l ++ +++ ++ FUN_002033-T1 434 DLLGICWIALAHIV 447 76666666666555 PP >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.4 2.1e-08 9.2e-05 1 61 [. 7 69 .. 7 98 .. 0.73 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 2.1e-08 THAP 1 CavpgCknkskskskkk.vsfhrfPkdkerrkkWlknikredlekkkkkksrvCskHFeee........l 61 Ca C+n+ + +k v+++++P d+e+r+k+ +k+e+ + +k+ ++Cs+H ++ FUN_002033-T1 7 CASALCHNSWR----TKgVRYYNLPVDPELRRKYQLVLKNENVNWTKQ---VICSAHWSRGerlspddiP 69 88899**9322....3339***************99999997766554...9******433444443330 PP >> DDE_Tnp_1 Transposase DDE domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.0001 0.43 78 198 .. 333 445 .. 316 447 .. 0.74 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0001 DDE_Tnp_1 78 rlvlaDaGYa.gkelldkleekgvdylirl..kknaklerk..........r.rrgrlrkkgklkiltksdklkgrvtntnsellsaetlaelyrr 159 ++v++DaGYa +++ ++++ +i + k++++l +k ++ + + + + ++ + d+ ++ +++++ FUN_002033-T1 333 PRVFVDAGYAdYEQITEQID------VIDYcpKGKVVLTDKgfaisdlcheKgVNHNRPPMKFNTQYDENDISLNF---------------DIATL 407 56677777774455555555......44445455555555566666666664468888888889999999999999...............***** PP DDE_Tnp_1 160 RwqiErvFkwlKrqfgldrlryrklnaveaellllalay 198 R+ E++++++ + + ++++ + + + + ++ +ala+ FUN_002033-T1 408 RIYNENAIGRIRD-WSILNKYWPSGRVDLLGICWIALAH 445 *************.**99999988887777777777765 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 1.4 5.6e-05 0.24 49 104 .. 153 208 .. 140 216 .. 0.90 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 5.6e-05 DUF1664 49 qleqvseslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvk 104 +l++ +sl + k Ls+++ ++++ l+e++++++++k e + +++++++k++++ FUN_002033-T1 153 SLQSQNTSLISENKALSEKVLKMEQLLQEMTAVQEKMKFERYSFEQKLKKMKFEFN 208 5677788999999**************************************99987 PP >> DUF7590 Domain of unknown function (DUF7590) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.3 7.6e-05 0.32 57 101 .. 116 163 .. 114 187 .. 0.87 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 7.6e-05 DUF7590 57 lsarqrarPRedehvfgdfs...srstkrikiqptnveleeaeallis 101 +s+r+r+ P+e + g+++ +r + ri+++++n l++ ++ lis FUN_002033-T1 116 KSTRKRKAPKERPFSPGNMQpvkKRRKTRISLEKENLSLQSQNTSLIS 163 69*****************8664688899***********99988888 PP >> Phage_scaffold Phage capsid assembly scaffolding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.5 0.15 6.5e+02 51 98 .. 75 123 .. 74 128 .. 0.84 2 ? 10.5 2.5 0.00015 0.63 38 97 .. 146 207 .. 130 212 .. 0.81 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.15 Phage_scaffold 51 keadkqleelkkkdn.eelkkkieelqeknkkkkaeyeaklaelkldsa 98 +e++++ e l kk + lkkk+ q ++ ++ e +l+ +++ +a FUN_002033-T1 75 EEQQEKFESLLKKTPsKSLKKKVVCVQRALVEANRETRGELKSTRKRKA 123 578999999999966699*****99999998888888899999999887 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00015 Phage_scaffold 38 klkeekkelkkqlkeadkqleelkkk..dneelkkkieelqeknkkkkaeyeaklaelklds 97 +l++e+ +l++q + + ++l++k + e+l ++ + qek k + + +e+kl+++k+++ FUN_002033-T1 146 SLEKENLSLQSQNTSLISENKALSEKvlKMEQLLQEMTAVQEKMKFERYSFEQKLKKMKFEF 207 455666677777777777778888888888******************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (467 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1795 (0.0702682); expected 510.9 (0.02) Passed bias filter: 738 (0.0288902); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4528.44 // Query: FUN_002034-T1 [L=718] Description: FUN_002034 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-06 28.9 0.0 5e-06 27.3 0.0 1.9 2 YqaJ YqaJ-like viral recombinase domain ------ inclusion threshold ------ 0.028 13.8 0.1 0.053 12.9 0.1 1.4 1 DAHP_synth_1 DAHP synthetase I family 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 SAP SAP domain Domain annotation for each model (and alignments): >> YqaJ YqaJ-like viral recombinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 1.3 1.1e+04 131 144 .. 35 48 .. 10 52 .. 0.68 2 ! 27.3 0.0 5.8e-10 5e-06 2 149 .. 491 622 .. 490 623 .. 0.85 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 1.3 YqaJ 131 kipeeYmlQvqhql 144 k eY++Q+ +l FUN_002034-T1 35 KWSLEYIQQCLMKL 48 45567888887766 PP == domain 2 score: 27.3 bits; conditional E-value: 5.8e-10 YqaJ 2 WleaRrkgitaSdaaaalglnpykssvslwlektgesieaaklepekekkavawGkelEpiareeYeertgvkvrevngllkhpeekfllaspDgi 97 W+++R + +t S ++ ++gl+ k+ + +++ ++ + i+ k++p k + +Gk++E a +++ +t+ v+ g++ hp+++ + spDg+ FUN_002034-T1 491 WFDLRIGKVTCSIIGYLVGLAGEKEHLHYLTCIKNK-IDPNKVKPRK-FASFTRGKQFESEAIKAFVSETKLPVTS-CGFFTHPNDNKYGGSPDGV 583 *******************99999999988888777.4444555665.555669**********************.6****************** PP YqaJ 98 vskkrdgkkgilEiKtpfsatfvkslwgeadsdkipeeYmlQvqhqlavTga 149 + +lE+Kt + ++ +i + +lQ +q+a+Tga FUN_002034-T1 584 G----P--GFLLEVKTRVA---GSDGP----LMAITAHHLLQTNYQMAMTGA 622 9....4..599*****999...33222....34799999**********997 PP >> DAHP_synth_1 DAHP synthetase I family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.1 6.2e-06 0.053 149 262 .. 230 347 .. 219 353 .. 0.73 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 6.2e-06 DAHP_synth_1 149 aaekilflgvtkgiilcerglrgge..ktnrnvldvsavkilkeethlpvmvDvsHansrkdgkrqkkvlelakaaiaaG..iaGvmiEvhpnpgk 240 +k + gvtk+i+lc++ l+ ++ + r++ld s +k + ++++ + + D +s + +v e++ + ++ G +Gv +E+h+ ++ FUN_002034-T1 230 KIQKWHRKGVTKQIELCHVPLSSFRnvRSSRKTLDSSCAKRKVNFSNDQALTDELVEKSDWS---KRDVNEMV-SRLKTGiqETGVNVESHIYDQL 321 4567788999**************96667778888777777777776699999765555555...55566555.4577773347************ PP DAHP_synth_1 241 alsd....gkqqlklgksetdacilk 262 + d qql++++ +++++l+ FUN_002034-T1 322 KKFDvksgLFQQLHYNCNYRLKNALQ 347 **996554457788877777776665 PP >> SAP SAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 1.9e-05 0.16 6 34 .. 37 65 .. 32 66 .. 0.79 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 1.9e-05 SAP 6 tvseLKeeLkkrGLptsGkKaeLieRLke 34 + ++ L k+G +tsG+K+ L++R+ + FUN_002034-T1 37 SLEYIQQCLMKLGQSTSGTKELLVKRIVN 65 55556667889999************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (718 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1027 (0.0402036); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6867.20 // Query: FUN_002037-T1 [L=189] Description: FUN_002037 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.082 13.5 0.0 0.11 13.1 0.0 1.3 1 DUF613 Protein of unknown function (DUF613) Domain annotation for each model (and alignments): >> DUF613 Protein of unknown function (DUF613) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 4.4e-06 0.11 8 83 .. 74 158 .. 67 185 .. 0.75 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 4.4e-06 DUF613 8 kekeyWeefsllelyvnnk......kvg...kekeniteleYilLDlflyGPlkikvseyekitkiikertkrykklleekkisg 83 + ++++ee +l ++k kv k+n +el LDl++ G +++ ++ +e+ t+ + e++++y+++ + + + FUN_002037-T1 74 RVEKFYEETCHCKLAADEKpcsttlKVDdfvDCKNNCSELSSTELDLVILGAIQCSLNCNETSTSGRAEKNRQYTRMGYYYHGQR 158 5556666666666666666555555333555589999***************************************966554444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (189 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 998 (0.0390683); expected 510.9 (0.02) Passed bias filter: 475 (0.0185946); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1951.85 // Query: FUN_002038-T1 [L=624] Description: FUN_002038 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (624 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1072 (0.0419652); expected 510.9 (0.02) Passed bias filter: 715 (0.0279898); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.40u 0.36s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 6021.58 // Query: FUN_002039-T1 [L=440] Description: FUN_002039 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (440 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1773 (0.0694069); expected 510.9 (0.02) Passed bias filter: 486 (0.0190252); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.40 # Mc/sec: 4383.72 // Query: FUN_002040-T1 [L=1129] Description: FUN_002040 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-08 34.5 0.1 0.049 14.2 0.0 4.5 4 NHL NHL repeat ------ inclusion threshold ------ 0.15 12.3 0.0 0.63 10.3 0.0 1.9 2 DUF7136 Domain of unknown function (DUF7136) Domain annotation for each model (and alignments): >> NHL NHL repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.0 9.4e-05 1.2 1 26 [. 445 469 .. 445 470 .. 0.94 2 ? -2.6 0.0 0.81 1e+04 10 21 .. 600 611 .. 599 615 .. 0.79 3 ! 14.2 0.0 3.8e-06 0.049 3 27 .. 626 649 .. 625 650 .. 0.94 4 ! 4.9 0.0 0.0033 42 2 25 .. 682 704 .. 681 705 .. 0.87 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 9.4e-05 NHL 1 fnrPhGvavdsdGdiyVaDsenhrvq 26 f++P+G++ + + ++V+Ds+n +++ FUN_002040-T1 445 FREPSGLCSF-KTILFVCDSGNGCIR 469 899******9.99***********97 PP == domain 2 score: -2.6 bits; conditional E-value: 0.81 NHL 10 dsdGdiyVaDse 21 +s+ i+V Ds+ FUN_002040-T1 600 TSNLSILVIDSR 611 58999*****86 PP == domain 3 score: 14.2 bits; conditional E-value: 3.8e-06 NHL 3 rPhGvavdsdGdiyVaDsenhrvqv 27 +P+G++ + +G +y+++s nh++++ FUN_002040-T1 626 SPSGLCFL-NGSFYISNSSNHTIVK 649 6******9.*************986 PP == domain 4 score: 4.9 bits; conditional E-value: 0.0033 NHL 2 nrPhGvavdsdGdiyVaDsenhrv 25 +PhG+ + + ++V+Ds+n + FUN_002040-T1 682 HSPHGLETF-GKTLFVCDSGNKAI 704 679999999.99*********887 PP >> DUF7136 Domain of unknown function (DUF7136) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 4.9e-05 0.63 8 54 .. 568 612 .. 563 644 .. 0.84 2 ? -1.9 0.0 0.26 3.3e+03 42 87 .. 934 981 .. 929 1013 .. 0.72 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 4.9e-05 DUF7136 8 vDLvFPRNeTYapselfPiVFAiqnpelasslnpsisyslwnednss 54 + Lv+PR +T ps+++P+ +A+q +l + n++ + s+ d+++ FUN_002040-T1 568 LHLVYPRKDT--PSNILPVALAFQDYKLYVASNLTSNLSILVIDSRK 612 57*******8..**************999888888777776666655 PP == domain 2 score: -1.9 bits; conditional E-value: 0.26 DUF7136 42 sisyslwnednsssslasgsldlreanlss..tsdpyflydstnklnn 87 is+sl ++++ss ++ +++l +an ss +++p + d + k n+ FUN_002040-T1 934 PISFSLQQRQDSSYDVLTEDLAAGHANSSSysQDNPVIQCDILFKQNE 981 588899999999988889999988888888877777776666555444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 873 (0.034175); expected 510.9 (0.02) Passed bias filter: 520 (0.0203562); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.44u 0.41s 00:00:00.85 Elapsed: 00:00:00.43 # Mc/sec: 10646.44 // Query: FUN_002041-T1 [L=333] Description: FUN_002041 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.21 12.8 6.4 0.51 11.6 6.4 1.6 1 TORC_N Transducer of regulated CREB activity, N terminus Domain annotation for each model (and alignments): >> TORC_N Transducer of regulated CREB activity, N terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 6.4 2e-05 0.51 11 52 .. 22 62 .. 20 75 .. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 2e-05 TORC_N 11 lqkqkqaEetaaFeriMkevtatkrdetqssnqkkqqlelsl 52 +qkqk E ++Fe+iM e + ++e++ + ++ q+le + FUN_002041-T1 22 MQKQKREEAVRQFEKIMAENLKIAKQEKELKAKR-QNLERLE 62 79*****************999998888855444.6666543 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (333 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2577 (0.100881); expected 510.9 (0.02) Passed bias filter: 1094 (0.0428264); expected 510.9 (0.02) Passed Vit filter: 101 (0.00395381); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 3313.22 // Query: FUN_002042-T1 [L=352] Description: FUN_002042 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.5 0.1 0.2 11.8 0.1 1.2 1 DUF7391 Family of unknown function (DUF7391) Domain annotation for each model (and alignments): >> DUF7391 Family of unknown function (DUF7391) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 7.7e-06 0.2 33 92 .. 93 149 .. 91 163 .. 0.88 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 7.7e-06 DUF7391 33 klglleelDfftkellpeevkkkdeeaekkeikevledpekfakmldvvnkvvvaavvkP 92 ++++++++D f k l +++ e+ ++ +i++ ++ + ++++ +v k++ a v+P FUN_002042-T1 93 RVDIANQVDKFKKSLAKQK---ISESTRRTKITNFIAQRQSRQEFKPAVGKLIDRAHVDP 149 5799***********9655...666777799*************************9999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (352 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 878 (0.0343707); expected 510.9 (0.02) Passed bias filter: 645 (0.0252496); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3493.68 // Query: FUN_002043-T1 [L=250] Description: FUN_002043 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 1 rve_3 Integrase core domain ------ inclusion threshold ------ 0.042 14.6 0.1 0.068 14.0 0.1 1.3 1 Imm74 Immunity protein 74 3.4 7.4 3.5 16 5.2 0.0 2.0 2 NOA36 NOA36 protein Domain annotation for each model (and alignments): >> rve_3 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 2.6e-06 0.022 2 32 .. 3 33 .. 2 49 .. 0.85 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 2.6e-06 rve_3 2 gikisyiepgkPqqNglvEsfngtlrdelln 32 g ++ ++ P+qNg Es ++++++ l FUN_002043-T1 3 GFEWNFTPADAPWQNGTSESLIRSVKRSLKA 33 7799**********************98765 PP >> Imm74 Immunity protein 74 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.1 8e-06 0.068 29 74 .. 43 89 .. 24 93 .. 0.77 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 8e-06 Imm74 29 nedkadfvvy.kdditkWdaPhesepitkeevqaivdaieeeladkg 74 e ++ f ++ ++ +++W P ++e+++ e+ + ++iee++ +++ FUN_002043-T1 43 SELQTRFPALmPHIVKQWRLPYDDEEFESEDSDNESEEIEEDAFEND 89 55666665441455799**********************99876655 PP >> NOA36 NOA36 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 3.7 0.08 6.8e+02 275 293 .. 66 84 .. 57 97 .. 0.43 2 ? 5.2 0.0 0.0019 16 88 113 .. 189 214 .. 183 226 .. 0.90 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.08 NOA36 275 dddddddeedddeeedded 293 d++ +++++d+++ee +ed FUN_002043-T1 66 DEEFESEDSDNESEEIEED 84 1221222222222211111 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0019 NOA36 88 gvyttglamvgaicdfceawvchgrk 113 g+++ l m+ i fce +v gr+ FUN_002043-T1 189 GIFSILLRMIEGIDGFCEPFVNFGRN 214 99**********************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (250 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 883 (0.0345665); expected 510.9 (0.02) Passed bias filter: 738 (0.0288902); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2469.28 // Query: FUN_002044-T1 [L=158] Description: FUN_002044 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (158 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 396 (0.0155021); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1627.33 // Query: FUN_002045-T1 [L=124] Description: FUN_002045 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.32 10.6 0.7 0.41 10.3 0.7 1.1 1 Zip ZIP Zinc transporter 0.74 8.7 2.5 0.85 8.5 2.5 1.0 1 Cellulose_synt Cellulose synthase 3.7 8.3 7.2 1.1 9.9 4.7 1.4 2 RNA_pol_Rpc4 RNA polymerase III RPC4 Domain annotation for each model (and alignments): >> Zip ZIP Zinc transporter # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.7 4.9e-05 0.41 90 164 .. 22 96 .. 21 122 .. 0.67 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 4.9e-05 Zip 90 lveklltllverktpkkeksshshkatvksvseeeveeseekedhgseeksdadskeklkkgkeekseeekeks......e 164 ++ek+l++++++ + + ++++v+s+++++++++e ++d+++ ++s+a++k++++k+k++ s+ ++ + + FUN_002045-T1 22 MIEKILSNFFGS------NPKIIPCSSVSSMAANPCKGDETSSDEEDAARSEAPKKKRKRKSKSSASQMIEYLKefkddkQ 96 689999999999......555567777888888888888888887777888888777777777776666555543332222 PP >> Cellulose_synt Cellulose synthase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 2.5 0.0001 0.85 299 366 .. 41 114 .. 22 122 .. 0.65 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0001 Cellulose_synt 299 kkeksvvsslclgkrkkkkkkkkek......kkkaakkkeseaeilaledidealegaeeekssllsqlklekk 366 ++ +s+++ c g + ++ ++ ++ k+k + k+++++ i l++++++ +++e+ek + l+++++ek FUN_002045-T1 41 SSVSSMAANPCKGDETSSDEEDAARseapkkKRKRKSKSSASQMIEYLKEFKDDKQKEEKEKLAALNKMHMEKM 114 444455566666655544433333233443244444555666778889999999999*************9996 PP >> RNA_pol_Rpc4 RNA polymerase III RPC4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 1.1 9.1e+03 64 75 .. 9 20 .. 2 27 .. 0.39 2 ? 9.9 4.7 0.00013 1.1 19 83 .. 52 116 .. 34 119 .. 0.74 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 1.1 RNA_pol_Rpc4 64 kekastlkdlpe 75 +e + ++ ++ FUN_002045-T1 9 SEASMAETAAKQ 20 222222233333 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00013 RNA_pol_Rpc4 19 ekeeskekeeeeeeekeeeekekeekeekeekkkkkkeekkkkkskekastlkdlpeGkiGkLrv 83 +++e++++ee++++++++++k+k+++++ +++ + +e k++k+ke++++l+ l + ++ k++v FUN_002045-T1 52 KGDETSSDEEDAARSEAPKKKRKRKSKSSASQMIEYLKEFKDDKQKEEKEKLAALNKMHMEKMNV 116 45566666677777777777778888888888888888899999999999999999999999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 3739 (0.146369); expected 510.9 (0.02) Passed bias filter: 1147 (0.0449012); expected 510.9 (0.02) Passed Vit filter: 102 (0.00399295); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.43s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 1243.07 // Query: FUN_002046-T1 [L=193] Description: FUN_002046 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.03 14.7 0.0 0.062 13.7 0.0 1.5 1 RRM_1 RNA recognition motif 0.23 12.0 0.0 0.37 11.3 0.0 1.3 1 Gp38_N Phage tail fibre adhesin Gp38 N-terminal dom 0.3 10.9 0.0 0.44 10.3 0.0 1.2 1 Dehydratase_hem Haem-containing dehydratase Domain annotation for each model (and alignments): >> RRM_1 RNA recognition motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 7.3e-06 0.062 1 25 [. 60 84 .. 60 89 .. 0.91 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 7.3e-06 RRM_1 1 lfVgnLppdvteeeLkelFskfGpi 25 +++++Lp++v +++ ++Fs + ++ FUN_002046-T1 60 VYIRDLPYEVPSDDVVDFFSSYDRV 84 8********************9887 PP >> Gp38_N Phage tail fibre adhesin Gp38 N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 4.3e-05 0.37 14 31 .. 135 152 .. 133 155 .. 0.92 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 4.3e-05 Gp38_N 14 aeTGqrWmsaAgaaLrlg 31 +eTG +W s+A a +rl+ FUN_002046-T1 135 SETGREWASKAKAHIRLQ 152 79**************96 PP >> Dehydratase_hem Haem-containing dehydratase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 5.1e-05 0.44 256 292 .. 140 177 .. 131 185 .. 0.91 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 5.1e-05 Dehydratase_hem 256 kwakshktHlaifkgflkhakklg.eerklrlwhEvsv 292 +wa++ k H+++ +++ ak+++ + +lr w E+ + FUN_002046-T1 140 EWASKAKAHIRLQVKAVLLAKEFDlTNSDLRRWTEIDI 177 7***********************7777*******865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (193 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 490 (0.0191818); expected 510.9 (0.02) Passed bias filter: 465 (0.0182032); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1920.42 // Query: FUN_002047-T1 [L=360] Description: FUN_002047 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-07 31.6 11.3 2e-07 31.0 10.2 1.6 1 DUF4616 Domain of unknown function (DUF4616) 0.0076 16.9 1.4 0.015 15.9 1.4 1.5 1 Flagellin_N Bacterial flagellin N-terminal helical region ------ inclusion threshold ------ 0.017 15.3 2.4 0.017 15.3 2.4 2.3 2 Mis12 Mis12 protein 0.022 15.1 6.0 0.022 15.1 6.0 2.5 3 NET2A NET2A-like domain 0.023 15.0 0.2 0.46 10.9 0.0 2.4 2 PSME4_C Proteasome activator complex subunit 4-like, C- 0.082 13.6 0.8 0.4 11.4 0.8 2.2 1 GAT GAT domain 0.14 12.9 3.1 2.7 8.7 0.2 2.6 3 DUF7971 Family of unknown function (DUF7971) 0.23 12.2 5.2 0.092 13.5 1.3 2.3 2 Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.88 9.9 6.6 0.09 13.1 1.5 1.8 2 RB_A Retinoblastoma-associated protein A domain 3 8.5 7.8 0.3 11.7 1.3 2.3 2 OmpH Outer membrane protein (OmpH-like) 4 8.4 6.1 6 7.8 0.4 2.9 2 HSCB_C HSCB C-terminal oligomerisation domain Domain annotation for each model (and alignments): >> DUF4616 Domain of unknown function (DUF4616) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.0 10.2 8.5e-11 2e-07 283 463 .. 113 284 .. 95 292 .. 0.80 Alignments for each domain: == domain 1 score: 31.0 bits; conditional E-value: 8.5e-11 DUF4616 283 ssGqknarrkrdlvlsklvhnvhnhvtndkrfnGsesiksswnisvvkflleklkqelvarshnytdkelkGacvayfltkrreyrnslnpfkglk 378 +G+k r k lvl vh hn ++++G e + s n+ v +++++ l +r+ +++ ++ + y rr + +k FUN_002047-T1 113 DNGKKRKRTKSSLVLQEEVHKFHNSRDVSNQYKGRELVNSPHNMRVTQLIVNEL-----CRHGEFAKTTVQRTAKKYHEHIRRTALGKI--TEDVK 201 46899999999*************9999999******************99876.....456677777777778888887776544443..46899 PP DUF4616 379 ekeekklrsrryrlfanrssivrllspedqrlwkdvteelms.deedsldepGvwvarpprfraqrltelcyrldans.khGtkanr 463 +++k lr r + r ++v+ + r + +++e ms d++++ e G w++rpp +r+ lt + +ld k + an+ FUN_002047-T1 202 IRNKKNLRKE--RKYERRRGFVKS--ETESRAFATLSKEHMSsDDDEAEGETGKWMSRPPMYRSTTLTLFLNKLDKRCdKNESSANK 284 9999999864..568899999984..556667777777777616666778*******************999999764255666665 PP >> Flagellin_N Bacterial flagellin N-terminal helical region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 1.4 6.6e-06 0.015 23 97 .. 28 101 .. 11 114 .. 0.84 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 6.6e-06 Flagellin_N 23 kaqerlstGlrinsalddaaglaiavslrsqiaglsqlvrnnslgiqrlqtaegalsevakilqrikelavqasn 97 ++ +r+s+G+ sa+ l+ +++++ iagls+ ++ + +i+ +q ++ +++e+++ ++ + +++ + + FUN_002047-T1 28 SSTSRISSGSGC-SASVESTPLSSRETMQKLIAGLSACQKSMEEVIKEVQSSNDRIEELTDKVKALHDKVEKNMT 101 577899999987.566677788999*******************************************9977654 PP >> Mis12 Mis12 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 2.4 7.5e-06 0.017 145 236 .. 53 134 .. 39 136 .. 0.72 2 ? -2.4 3.2 1.9 4.4e+03 145 169 .. 203 246 .. 171 307 .. 0.53 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 7.5e-06 Mis12 145 kneallaelrkllssvselleeeekkakeelkslkpldetlefllsqlkalqdkleelksklae.elqkkeeeekksweserdeyiesktkkl 236 ++l+a l+++++s++e k+ ++ ++ +e+l+ ++kal+dk+e+ +++ + +++++ ++ kk ++++ + ++++++k+ FUN_002047-T1 53 TMQKLIAGLSACQKSMEE-----------VIKEVQSSNDRIEELTDKVKALHDKVEKNMTSDHNgDSENSGDNGKKRKRTKSSLVLQEEVHKF 134 344455555555555555...........5559************************777776644444445558888888888888887765 PP == domain 2 score: -2.4 bits; conditional E-value: 1.9 Mis12 145 kneallaelrkllssvselleeee...................k 169 +n++ l++ rk++++ ++++e+e + FUN_002047-T1 203 RNKKNLRKERKYERRRGFVKSETEsrafatlskehmssdddeaE 246 55555555555555555555544444444444444444333332 PP >> NET2A NET2A-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 6.0 9.6e-06 0.022 32 130 .. 61 161 .. 49 168 .. 0.68 2 ? -2.6 0.6 2.4 5.5e+03 99 108 .. 203 212 .. 170 247 .. 0.43 3 ? -0.5 1.2 0.56 1.3e+03 61 136 .. 269 345 .. 262 355 .. 0.54 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 9.6e-06 NET2A 32 LakLqekqeksaeeakvEserikeareklkaLkkeflsdqteekekkekeeekevsetkeleeevesleqek...keleslrekikekfeansess 124 L+ q+ e++++e++ + ri+e+ +k+kaL ++++++ t++++ +++++ ++ ++ k++++ + l++e ++ ++ ++ k +ns ++ FUN_002047-T1 61 LSACQKSMEEVIKEVQSSNDRIEELTDKVKALHDKVEKNMTSDHNGDSENSGDNGKKRKRTKS-SLVLQEEVhkfHNSRDVSNQYKGRELVNSPHN 155 4556899999**************************999888877766665555444443332.22333333111444555556665555566666 PP NET2A 125 ltvtel 130 + vt+l FUN_002047-T1 156 MRVTQL 161 666665 PP == domain 2 score: -2.6 bits; conditional E-value: 2.4 NET2A 99 leqekkeles 108 ++++ e FUN_002047-T1 203 RNKKNLRKER 212 2222222222 PP == domain 3 score: -0.5 bits; conditional E-value: 0.56 NET2A 61 kaLkkeflsdqteekekkekeeekevsetkeleeevesleqekkeleslreki.kekfeansessltvtelaekIDe 136 ++L k++++++++ ++ +++++++ + +++ + ++e +++ e+ + + e++ e+++ e+ e++D+ FUN_002047-T1 269 NKLDKRCDKNESSANKRWRRTQVEKGAAINKEPPTNTPKWALSDEWKDIIERReNPQGEEEYENDVDAPEMQEEVDD 345 66777777766666655555554444433333222222222233333333332033455566667778888888875 PP >> PSME4_C Proteasome activator complex subunit 4-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.0002 0.46 6 46 .. 34 74 .. 29 81 .. 0.84 2 ? 1.5 0.1 0.17 3.9e+02 29 58 .. 162 191 .. 151 208 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.0002 PSME4_C 6 aavlglsAlvlafPydvPkwvpevLeeLakhasspagpikk 46 ++ g sA v+++P ++ + + ++++ L+++++s++++ik+ FUN_002047-T1 34 SSGSGCSASVESTPLSSRETMQKLIAGLSACQKSMEEVIKE 74 566799****************************9966554 PP == domain 2 score: 1.5 bits; conditional E-value: 0.17 PSME4_C 29 vLeeLakhasspagpikktvkktlseFkrt 58 ++ eL++h + ++ +++t+kk + +rt FUN_002047-T1 162 IVNELCRHGEFAKTTVQRTAKKYHEHIRRT 191 344599999999989999999998888887 PP >> GAT GAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.8 0.00017 0.4 19 66 .. 47 98 .. 40 106 .. 0.77 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00017 GAT 19 elldnelikeLyercksaqpkiqklieetsdeed....llaellqlNDelnq 66 l++ e++++L+ + + q+++ + i e+++ +d l+++ +l+D++ + FUN_002047-T1 47 PLSSRETMQKLIAGLSACQKSMEEVIKEVQSSNDrieeLTDKVKALHDKVEK 98 578999*********************9966665466677777777777765 PP >> DUF7971 Family of unknown function (DUF7971) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.2 0.0012 2.7 13 68 .. 43 98 .. 39 102 .. 0.89 2 ? 4.0 0.0 0.033 77 5 41 .. 155 191 .. 152 230 .. 0.83 3 ? -3.2 0.2 5.7 1.3e+04 26 32 .. 338 344 .. 316 358 .. 0.51 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0012 DUF7971 13 ldslPeddeeaaadmqraveglerrlneaieeaddeeeaasavvdaierleerler 68 ++s P ++ e+ + + +++ +++++e+i+e ++ ++ +++ d ++ l +++e+ FUN_002047-T1 43 VESTPLSSRETMQKLIAGLSACQKSMEEVIKEVQSSNDRIEELTDKVKALHDKVEK 98 67788888888888888888999*****************************9997 PP == domain 2 score: 4.0 bits; conditional E-value: 0.033 DUF7971 5 slgvPeeildslPeddeeaaadmqraveglerrlnea 41 ++ v + i+++l ++e a++ +qr+ ++++++++++ FUN_002047-T1 155 NMRVTQLIVNELCRHGEFAKTTVQRTAKKYHEHIRRT 191 5789999*************************99875 PP == domain 3 score: -3.2 bits; conditional E-value: 5.7 DUF7971 26 dmqrave 32 +mq+ v+ FUN_002047-T1 338 EMQEEVD 344 2222222 PP >> Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 1.3 4e-05 0.092 51 101 .. 50 100 .. 43 102 .. 0.92 2 ? -1.7 0.1 2 4.7e+03 69 93 .. 329 353 .. 309 358 .. 0.51 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 4e-05 Seryl_tRNA_N 51 erNelskeIgkakkkkedaeeliaevkelkeelkaleeelkeleaelekll 101 r +++k I+ +++ ++ ee i+ev++ ++++++l +++k+l +++ek + FUN_002047-T1 50 SRETMQKLIAGLSACQKSMEEVIKEVQSSNDRIEELTDKVKALHDKVEKNM 100 6788999*******99******************************99866 PP == domain 2 score: -1.7 bits; conditional E-value: 2 Seryl_tRNA_N 69 aeeliaevkelkeelkaleeelkel 93 e ++ e++ee+++++ ++el FUN_002047-T1 329 EYENDVDAPEMQEEVDDADSSESEL 353 3333334444555555555555544 PP >> RB_A Retinoblastoma-associated protein A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 1.5 3.9e-05 0.09 6 82 .. 47 124 .. 43 131 .. 0.79 2 ? -1.9 0.3 1.6 3.7e+03 55 55 .. 221 221 .. 170 285 .. 0.55 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3.9e-05 RB_A 6 alqsvkrLkellsglkdePsekLeeilksc..sedptekilkrvkelaekflkkyseeseeekssslakeiaekrlkla 82 l+s + +++l++gl+ + ++++ee++k++ s+d +e+++ +vk l++k++k+++++ + +++s ++ ++kr+k FUN_002047-T1 47 PLSSRETMQKLIAGLS-ACQKSMEEVIKEVqsSNDRIEELTDKVKALHDKVEKNMTSDHNGDSENSGDNGKKRKRTKSS 124 5678889999999999.5589999999997546777*****************99988888867776666666666554 PP == domain 2 score: -1.9 bits; conditional E-value: 1.6 RB_A 55 l 55 FUN_002047-T1 221 V 221 1 PP >> OmpH Outer membrane protein (OmpH-like) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 1.3 0.00013 0.3 7 76 .. 54 136 .. 53 164 .. 0.71 2 ? -0.1 0.8 0.59 1.4e+03 18 77 .. 171 230 .. 155 248 .. 0.61 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00013 OmpH 7 vqkileespegkaaqkqlekefkkrqkelekkekelqklqeklqaeasels...se.......keekeke....lqkkeqelqe 76 +qk+++ + ++ ++++ ke ++ ++ +e++ +++++l +k +++++ se k+++ + lq+++ ++ + FUN_002047-T1 54 MQKLIAGLSACQKSMEEVIKEVQSSNDRIEELTDKVKALHDKVEKNMTSDHngdSEnsgdngkKRKRT-KsslvLQEEVHKFHN 136 89******************************************666543233333455544222222.255555555555544 PP == domain 2 score: -0.1 bits; conditional E-value: 0.59 OmpH 18 kaaqkqlekefkkrqkelekkekelqklqeklq.aeaselsse.keekekelqkkeqelqeq 77 + a++++++++kk+ + ++ +++l k e+ + +++++l +e k e+++ + k e+e +++ FUN_002047-T1 171 EFAKTTVQRTAKKYHEHIR--RTALGKITEDVKiRNKKNLRKErKYERRRGFVKSETESRAF 230 5577777888888888887..66666666666654433333222334444466666665554 PP >> HSCB_C HSCB C-terminal oligomerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 0.4 0.0026 6 13 46 .. 69 102 .. 67 113 .. 0.86 2 ? 2.0 0.9 0.17 4e+02 11 29 .. 338 356 .. 338 358 .. 0.82 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0026 HSCB_C 13 rEeleeaesdeeeleelkkenkerikeleeklee 46 E + e++s+++++eel +++k+ ++++e+++ + FUN_002047-T1 69 EEVIKEVQSSNDRIEELTDKVKALHDKVEKNMTS 102 68999**8877*****************999876 PP == domain 2 score: 2.0 bits; conditional E-value: 0.17 HSCB_C 11 ewrEeleeaesdeeeleel 29 e++Ee+++a+s+e+el ++ FUN_002047-T1 338 EMQEEVDDADSSESELSDF 356 789******7777999876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (360 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2415 (0.094539); expected 510.9 (0.02) Passed bias filter: 824 (0.0322568); expected 510.9 (0.02) Passed Vit filter: 114 (0.00446271); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.38u 0.38s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3479.29 // Query: FUN_002050-T1 [L=120] Description: FUN_002050 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.28 11.5 1.3 0.37 11.1 1.3 1.2 1 FAM176 FAM176 family 0.51 9.0 4.5 0.5 9.1 4.5 1.0 1 CDC45 CDC45 4.2 7.7 8.3 4.5 7.6 8.3 1.1 1 Sigma70_ner Sigma-70, non-essential region 4.2 5.9 19.1 4.7 5.7 19.1 1.0 1 DNA_pol_phi DNA polymerase phi 8.8 6.0 5.4 9.2 5.9 5.4 1.0 1 DUF2722 Protein of unknown function (DUF2722) 9.1 4.9 10.6 10 4.7 10.6 1.0 1 Nop14 Nop14-like family Domain annotation for each model (and alignments): >> FAM176 FAM176 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 1.3 8.7e-05 0.37 63 115 .. 26 78 .. 10 89 .. 0.72 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8.7e-05 FAM176 63 eeseedeedseeeeeeeeedsseseikdeltelekssefertlsvnvftsaee 115 ++++d++d+ +++++++d++ ++ ++++ + ++ ++f + l ++ ++s e+ FUN_002050-T1 26 GDDDNDDDDASVDDDDDDDDTVAADNDNDMDDGDSCDQFVACLHADYHESEED 78 22333344444566777888888888888988899999999999998888875 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 4.5 0.00012 0.5 134 164 .. 21 54 .. 3 103 .. 0.45 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00012 CDC45 134 ede...eeeeeddeeeeeeeeeeedeeeeeedee 164 +++ +++++dd+ + +++++++d+ ++d++ FUN_002050-T1 21 DHDdsgDDDNDDDDASVDDDDDDDDTVAADNDND 54 1111111111111111111111111111111111 PP >> Sigma70_ner Sigma-70, non-essential region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 8.3 0.0011 4.5 40 75 .. 19 56 .. 7 92 .. 0.58 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0011 Sigma70_ner 40 aeeeeeeeeeeeeeeeee..ddddeedeeseeadegel 75 a++ +++ ++++++++++ dddd++d+ ++++d+ + FUN_002050-T1 19 ADDHDDSGDDDNDDDDASvdDDDDDDDTVAADNDNDMD 56 22333333333333333342222233333333333333 PP >> DNA_pol_phi DNA polymerase phi # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 19.1 0.0011 4.7 646 701 .. 20 76 .. 10 96 .. 0.50 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0011 DNA_pol_phi 646 dddeeededdeededseedddeedddeeeededdedvdeed.eelreklaealgesn 701 dd +++++dd++d+d + ddd++ddd d+d++ +d + +++ + l + +es+ FUN_002050-T1 20 DDHDDSGDDDNDDDDASVDDDDDDDDTVAADNDNDMDDGDScDQFVACLHADYHESE 76 333333334444444443444333333333333333333225588888877777776 PP >> DUF2722 Protein of unknown function (DUF2722) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 5.4 0.0022 9.2 341 383 .. 20 74 .. 2 94 .. 0.56 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0022 DUF2722 341 qekeddddddddskerkkeeekdkkkvsikdddkdisedssv............k 383 ++d+ ddd+d+++ +++++d ++ d+d+d+++ s + FUN_002050-T1 20 DDHDDSGDDDNDDDDASVDDDDDDDDTVAADNDNDMDDGDSCdqfvaclhadyhE 74 2333333444444444455555544555556777776666655555666655554 PP >> Nop14 Nop14-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 10.6 0.0024 10 356 404 .. 20 64 .. 10 96 .. 0.38 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.0024 Nop14 356 lveseseleeeeeeedeeeeeeeeeeeeeeededdlsdleseeeeedel 404 +++++s +++ ++++d + +++++++++ d+d+ +d + ++ d++ FUN_002050-T1 20 DDHDDSGDDD-NDDDDASVDDDDDDDDTVAADNDNDMD---DGDSCDQF 64 2222222222.122222222222222222222222222...22223332 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 793 (0.0310433); expected 510.9 (0.02) Passed bias filter: 435 (0.0170288); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1208.22 // Query: FUN_002051-T1 [L=157] Description: FUN_002051 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0053 17.5 0.1 4.6 8.1 0.0 2.3 2 HetE-N Het-E N-terminal domain ------ inclusion threshold ------ 0.29 10.6 0.0 0.36 10.2 0.0 1.2 1 Glyco_hydro_88 Glycosyl Hydrolase Family 88 Domain annotation for each model (and alignments): >> HetE-N Het-E N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.1 0.0 0.00036 4.6 53 83 .. 16 46 .. 7 57 .. 0.77 2 ! 7.5 0.1 0.00054 6.9 38 82 .. 63 105 .. 58 121 .. 0.86 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.00036 HetE-N 53 klneelseeaierklleseellkileeikps 83 +e++ +ea+er + +e++ +il++++ FUN_002051-T1 16 IAAEKVLDEAMERFYRAHEDYHQILQTVEER 46 455667778*****************98843 PP == domain 2 score: 7.5 bits; conditional E-value: 0.00054 HetE-N 38 Ddstlealveeleklklneelseeaierklleseellkileeikp 82 D ++l+ l++ le+ ++ ++s + +++++++ +++il+++ p FUN_002051-T1 63 DGEALNDLADDLENCEITLKVSSRL--DQVNNKDRMVEILQKVPP 105 66899*************9988876..69************9875 PP >> Glyco_hydro_88 Glycosyl Hydrolase Family 88 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 2.8e-05 0.36 96 148 .. 15 68 .. 2 87 .. 0.82 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 2.8e-05 Glyco_hydro_88 96 kkaaeeladyvlaeaprtseGgfwh.kkiypeqmWlDgLfMalpflaklgkltk 148 aae++ d ++ +r++e + ++++++q+W+D L ++p+ + g++++ FUN_002051-T1 15 VIAAEKVLDEAMERFYRAHEDYHQIlQTVEERQAWIDKLSFGPPIRLNDGEALN 68 56788888889999999888777769***************9999887777666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1369 (0.0535917); expected 510.9 (0.02) Passed bias filter: 1073 (0.0420043); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.39 # Mc/sec: 1610.37 // Query: FUN_002052-T1 [L=255] Description: FUN_002052 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.9 1.5 0.31 11.7 0.9 1.8 2 HisK-N-like HisK-N-like globin domain of the ASK signalosome 0.15 12.5 1.4 0.2 12.1 0.7 1.5 1 DUF4330 Domain of unknown function (DUF4330) 0.71 10.8 4.2 0.29 12.0 1.6 1.7 2 DUF5667 Domain of unknown function (DUF5667) Domain annotation for each model (and alignments): >> HisK-N-like HisK-N-like globin domain of the ASK signalosome # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 0.47 4e+03 87 104 .. 11 28 .. 6 36 .. 0.74 2 ? 11.7 0.9 3.7e-05 0.31 10 80 .. 92 162 .. 76 176 .. 0.88 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.47 HisK-N-like 87 qlalylfqdavnkvLreh 104 + al ++ d++nk+++ h FUN_002052-T1 11 KAALEKYADSLNKIIQDH 28 567777888888887766 PP == domain 2 score: 11.7 bits; conditional E-value: 3.7e-05 HisK-N-like 10 ratLakvLtedeekiisawleslkqsseelklkkehlkqllsglreyirkkdrkqleeaikelkeeldfds 80 +a + vL+++++k ++ +es +++++++ ++++ k+ ls++ ++ ++ + q +ai++l ++++ + FUN_002052-T1 92 TAEVKSVLARNQKKAVNVREESSIKAMQQMHTSMAVSKNFLSSFLSTTQSSAHMQQGNAITQLPGQYQARE 162 566788*********************************************************99998855 PP >> DUF4330 Domain of unknown function (DUF4330) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.7 2.3e-05 0.2 70 122 .. 72 128 .. 58 152 .. 0.73 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 2.3e-05 DUF4330 70 ik..kegektniiirnqpagqvkiksvkvlprtvav.pqpdGsvkalpdPr.eepys 122 + k +++t+++ rnq g++++ksv +++ av +++s+ka+++ + ++++s FUN_002052-T1 72 KQttKREKRTSLLERNQNLGTAEVKSVLARNQKKAVnVREESSIKAMQQMHtSMAVS 128 2355799********************887777665156678888887744455555 PP >> DUF5667 Domain of unknown function (DUF5667) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.0 1.5 1.3e+04 62 72 .. 16 26 .. 9 40 .. 0.46 2 ? 12.0 1.6 3.5e-05 0.29 12 85 .. 63 147 .. 56 160 .. 0.78 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 1.5 DUF5667 62 eyeeqleqaee 72 +y + l+++ + FUN_002052-T1 16 KYADSLNKIIQ 26 33332222222 PP == domain 2 score: 12.0 bits; conditional E-value: 3.5e-05 DUF5667 12 kkliEeiqlaltfdeekkaellleiaeeRlaEaeallekgkeelaeelleeyeeqleqaeealas...........rlaeeakqa 85 k+l + ++++ t++ ek+++ll+++ + aE++ l++++++ ++ e ++++q+ + +a + ++++ q+ FUN_002052-T1 63 KRLSDGATTKQTTKREKRTSLLERNQNLGTAEVKSVLARNQKKAVNVREESSIKAMQQMHTSMAVsknflssflstTQSSAHMQQ 147 6777888889999******************************999999999999999998875455666666443333444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (255 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1884 (0.0737522); expected 510.9 (0.02) Passed bias filter: 761 (0.0297906); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2596.79 // Query: FUN_002053-T1 [L=287] Description: FUN_002053 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.056 14.0 0.0 0.11 13.1 0.0 1.4 1 DUF6584 Family of unknown function (DUF6584) Domain annotation for each model (and alignments): >> DUF6584 Family of unknown function (DUF6584) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 4.2e-06 0.11 59 160 .. 130 228 .. 119 235 .. 0.81 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 4.2e-06 DUF6584 59 ywyLeedkdpeekkavevfeksvnnspaqilraLkyrgdksklkteyaekkLealreevkeklgeevdesskaskekeeskket.kdklvtlgclv 153 ++y +d ++ ++ fe++ s ++ + + +++l+ + ++++++l +++ +l+++++ + + +++++ +++ kd+ vtlg+++ FUN_002053-T1 130 WSYVRDDLLDQREDN---FEDELS-SVMNVEDEDVWFNAEEHLQLSDNARRFSSLPSQCPGNLEQPQENTPTPQEKTDLDQEPLyKDANVTLGSVM 221 777777777777777...888888.777777666677777888899999*****************9999888888888888888********999 PP DUF6584 154 vvlaila 160 v+l++++ FUN_002053-T1 222 VLLVMFV 228 9966554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (287 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 882 (0.0345273); expected 510.9 (0.02) Passed bias filter: 578 (0.0226267); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.38s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2846.95 // Query: FUN_002054-T1 [L=70] Description: FUN_002054 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.2 0.1 0.2 11.4 0.1 1.4 1 Zn_ribbon_RanBP Zn-finger in Ran binding protein and others Domain annotation for each model (and alignments): >> Zn_ribbon_RanBP Zn-finger in Ran binding protein and others # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 7.9e-06 0.2 17 29 .. 31 43 .. 29 44 .. 0.88 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 7.9e-06 Zn_ribbon_RanBP 17 estkCvaCqapkp 29 ++ +Cv+C+a+k+ FUN_002054-T1 31 HAKACVQCEALKE 43 7899*******97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (70 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1120 (0.0438442); expected 510.9 (0.02) Passed bias filter: 601 (0.0235271); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 724.68 // Query: FUN_002055-T1 [L=368] Description: FUN_002055 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (368 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 765 (0.0299472); expected 510.9 (0.02) Passed bias filter: 624 (0.0244275); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3602.77 // Query: FUN_002057-T1 [L=166] Description: FUN_002057 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00081 18.9 0.0 0.0013 18.2 0.0 1.4 1 Mutator Mutator-like transposase ------ inclusion threshold ------ 0.056 13.5 0.0 0.069 13.2 0.0 1.1 1 WHD_DnaB DnaB N-terminal winged helix domain Domain annotation for each model (and alignments): >> Mutator Mutator-like transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 1e-07 0.0013 3 67 .. 95 152 .. 93 166 .] 0.73 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1e-07 Mutator 3 rivdvkelaellnslielhkekepeccklvllkidkerkkGlgskltlkCskCgyknsvrtlkke 67 +v +l++l + +++ h ++ ++ l+ dk+r+ Gl s ltl+C++C+ +++++t+ FUN_002057-T1 95 TMV---DLEKLSKAISSAHVCN----GGTLILQDDKTRRPGLMSELTLECNTCHESSPISTSMSV 152 566...5666666666666666....56777777888***********************99876 PP >> WHD_DnaB DnaB N-terminal winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 5.4e-06 0.069 170 218 .. 63 111 .. 23 120 .. 0.83 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 5.4e-06 WHD_DnaB 170 aFkklmardglrfedekedvlalyalaekyeldwyelyklaketavnqt 218 + +k m++++++f+ e++d + ++ e+++ ++++l kl+k+ ++ ++ FUN_002057-T1 63 TSRKKMEHKKIDFSSESSDNKSSFQTRESEGYTMVDLEKLSKAISSAHV 111 45789************************************99877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (166 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1258 (0.0492464); expected 510.9 (0.02) Passed bias filter: 643 (0.0251713); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1674.57 // Query: FUN_002058-T1 [L=107] Description: FUN_002058 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.017 16.0 0.2 0.042 14.8 0.0 1.6 1 DUF3106 Protein of unknown function (DUF3106) Domain annotation for each model (and alignments): >> DUF3106 Protein of unknown function (DUF3106) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 1.6e-06 0.042 25 67 .. 60 103 .. 54 106 .. 0.80 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.6e-06 DUF3106 25 eqreklleiaeryakltpeeqarvqermkewa.kLspeqreqar 67 ++++ l ++ae y++l+pe ++++ + +ew+ +L+pe++e+ + FUN_002058-T1 60 TRKKLLSDRAEWYNSLNPEGKENLSSDGAEWSsSLNPEDKENSK 103 56666778999999999999999999999996369999998866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (107 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 676 (0.0264631); expected 510.9 (0.02) Passed bias filter: 427 (0.0167156); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1084.31 // Query: FUN_002059-T1 [L=197] Description: FUN_002059 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (197 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 596 (0.0233314); expected 510.9 (0.02) Passed bias filter: 459 (0.0179683); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 2040.70 // Query: FUN_002060-T1 [L=135] Description: FUN_002060 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.069 13.2 0.0 0.095 12.8 0.0 1.4 1 Sec7 Sec7 domain Domain annotation for each model (and alignments): >> Sec7 Sec7 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 3.7e-06 0.095 92 154 .. 3 127 .. 1 135 [] 0.65 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3.7e-06 Sec7 92 rlpg.eaqkidrilekFaerYveqnpe...........................................................vfanadaayv 127 rlpg e q ++ +++k +++Y++++p +fa+ + FUN_002060-T1 3 RLPGeELQDLEVLVQKMSKKYIDAEPYaafnddadayysldpadpecretlqatdsdsdessddaslpippvqavkgalhlvcqiiEFAHYRTREK 98 8999778***************98888665555666666666666666666666666666666666666666666666666666655666666666 PP Sec7 128 laysiimLntdlhnpnv..kkkmtledFi 154 l+ +++ ++ lh + +k+ ++ dF+ FUN_002060-T1 99 LSTAVMKVSDILHDIRLksQKQSSILDFV 127 66666666666665555444555555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (135 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 741 (0.0290076); expected 510.9 (0.02) Passed bias filter: 474 (0.0185555); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1404.75 // Query: FUN_002061-T1 [L=138] Description: FUN_002061 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.046 14.4 3.2 0.065 14.0 3.2 1.3 1 zf-AD Zinc-finger associated domain (zf-AD) Domain annotation for each model (and alignments): >> zf-AD Zinc-finger associated domain (zf-AD) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 3.2 2.6e-06 0.065 14 70 .. 59 117 .. 40 120 .. 0.88 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.6e-06 zf-AD 14 pifepsese..ktlaelleellgielspkdllpkkiCerCleklqefysFrkrclesqa 70 + f+ +s+ k++a++ e+ i l + + +++C Cl e+ +F +rc ++++ FUN_002061-T1 59 CSFDGVKSSlyKPIASDFPECKVISLIVDADTERCVCIACLDMCVEITHFSRRCGSVRK 117 556677777899***************999999*********************98876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (138 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 514 (0.0201214); expected 510.9 (0.02) Passed bias filter: 280 (0.010961); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.35s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1403.74 // Query: FUN_002062-T1 [L=114] Description: FUN_002062 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-08 33.4 0.0 2.8e-08 33.4 0.0 1.1 1 Viral_alk_exo Viral alkaline exonuclease Domain annotation for each model (and alignments): >> Viral_alk_exo Viral alkaline exonuclease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.4 0.0 1.1e-12 2.8e-08 92 131 .. 64 103 .. 11 113 .. 0.84 Alignments for each domain: == domain 1 score: 33.4 bits; conditional E-value: 1.1e-12 Viral_alk_exo 92 qkelllliEretrgQsenslWelLRdgiisasklyeavkg 131 + e ++ +E+etr Qs+n+ W+ LR++ i+askl+ + g FUN_002062-T1 64 KLEECKQMEKETRDQSDNPFWHDLRKKRITASKLQRVAAG 103 5556999***************************987754 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (114 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 723 (0.028303); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1169.62 // Query: FUN_002063-T1 [L=116] Description: FUN_002063 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 362 (0.0141711); expected 510.9 (0.02) Passed bias filter: 343 (0.0134273); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1172.02 // Query: FUN_002064-T1 [L=135] Description: FUN_002064 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-07 30.6 0.0 6.9e-07 29.8 0.0 1.4 1 RVT_1 Reverse transcriptase (RNA-dependent DNA polymerase Domain annotation for each model (and alignments): >> RVT_1 Reverse transcriptase (RNA-dependent DNA polymerase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.0 2.7e-11 6.9e-07 79 174 .. 15 133 .. 3 135 .] 0.87 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 2.7e-11 RVT_1 79 eellrkltafkvpskliksllrvngee.egryewkglpqGlvlSPllfqlfmdellrelrkra................................. 140 eel++k ta+ ++ +++ +g++qG+ SP l++l+md ++r ++ + FUN_002064-T1 15 EELYKKTTAYMTDD----------P-DkKEFDVGAGVRQGGCESPRLYHLYMDFVMRVFKIEQekagikgvamkfripnhstnrserakysssgvt 99 44555555555552..........2.4499999***********************9988766789****************************** PP RVT_1 141 evtllvYaDDililskseeeleealeeveeflke 174 e ++ +aDD++++++s e++++a++++++fl + FUN_002064-T1 100 EHLWVGFADDTTLFFESVEDIQAAMNILSTFLTD 133 *****************************99975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (135 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 458 (0.0179291); expected 510.9 (0.02) Passed bias filter: 395 (0.0154629); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.42s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1368.72 // Query: FUN_002065-T1 [L=68] Description: FUN_002065 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.18 12.1 0.0 0.21 11.9 0.0 1.2 1 zf-C17orf113 C17orf113 probable zinc finger Domain annotation for each model (and alignments): >> zf-C17orf113 C17orf113 probable zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 8.3e-06 0.21 15 38 .. 4 29 .. 2 51 .. 0.72 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 8.3e-06 zf-C17orf113 15 mfCtlCkey.r..kkknpFakeGsknf 38 mfC++C+++ +k+ + +G++ + FUN_002065-T1 4 MFCKVCRAFpApvNKSSVLF-KGTSGI 29 ********986665555544.465555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (68 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 477 (0.0186729); expected 510.9 (0.02) Passed bias filter: 382 (0.014954); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 689.59 // Query: FUN_002068-T1 [L=130] Description: FUN_002068 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.099 12.9 0.2 0.14 12.4 0.2 1.3 1 DUF7225 Domain of unknown function (DUF7225) 0.2 12.3 0.0 5.8 7.6 0.0 2.2 2 Phenol_monoox Phenol hydroxylase conserved region Domain annotation for each model (and alignments): >> DUF7225 Domain of unknown function (DUF7225) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.2 1.1e-05 0.14 14 69 .. 27 81 .. 14 89 .. 0.79 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.1e-05 DUF7225 14 edeilsskeikellakkygtnpesvilsDyCYnrvnkGi.afdkhlfeyinrgeyky 69 +d++ + ++ik+ + ++++ v ++D+ Y +n Gi ++ h + i++ e+++ FUN_002068-T1 27 NDSVTQMSQIKDS--RMFKKKYTFVFPTDFDYQYTNTGIsQQAYHAAVQIGNIEWRC 81 5667777888874..668899999***************444567777777777776 PP >> Phenol_monoox Phenol hydroxylase conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.00046 5.8 19 61 .. 38 80 .. 34 83 .. 0.90 2 ? 2.4 0.0 0.019 2.4e+02 29 41 .. 104 116 .. 100 129 .. 0.75 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.00046 Phenol_monoox 19 dhllFaapfalplPpdmpFgalveavlagligahPdfaridws 61 d +F + +++ +P d ++ +++ ++++ a + +i+w FUN_002068-T1 38 DSRMFKKKYTFVFPTDFDYQYTNTGISQQAYHAAVQIGNIEWR 80 6789************************999999999999996 PP == domain 2 score: 2.4 bits; conditional E-value: 0.019 Phenol_monoox 29 lplPpdmpFgalv 41 + Ppd++Fg+l FUN_002068-T1 104 IYYPPDVTFGNLE 116 678*******984 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (130 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 957 (0.0374633); expected 510.9 (0.02) Passed bias filter: 695 (0.0272069); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.24u 0.40s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1312.93 // Query: FUN_002069-T1 [L=235] Description: FUN_002069 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-06 27.2 0.0 3.7e-06 26.9 0.0 1.1 1 DUF3987 Protein of unknown function (DUF3987) ------ inclusion threshold ------ 0.067 13.9 0.1 0.44 11.2 0.0 2.0 2 PPP5 PPP5 TPR repeat region 0.073 13.5 0.1 0.27 11.6 0.1 1.9 2 UNC45-central Myosin-binding striated muscle assembly centra 0.16 11.1 0.0 0.21 10.8 0.0 1.1 1 CENP-I Mis6 Domain annotation for each model (and alignments): >> DUF3987 Protein of unknown function (DUF3987) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.0 5.7e-10 3.7e-06 176 356 .. 2 187 .. 1 192 [. 0.73 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 5.7e-10 DUF3987 176 wdGdpls.vdRkgresehienprlslllmiQpsvlkellakegargdGllaRfLfalPd...stagwrdvdaepipdavleayearlrellaepea 267 + G++ s ++ ++r +e +n ++l+++Q + +++ l + +g+Gll RfL+++P+ +t + ++++ e+ ++ l+ +++ + e++ FUN_002069-T1 2 FSGEEASyRYATERVREIRSNTPFCILGATQ-APFAACLVTILDQGHGLLDRFLITFPKclrPTPQETEQAVEALTQSPLSSFDDIFLEIACL--- 93 5677777555555555444555555555555.555555546667899***********96664433333343456666667777777777777... PP DUF3987 268 eldegelepitlrLspeAkalfneffneiekrlapgggleeirdwasKlaenvaRlAgllhla..........edg..gearpisaetmeaAlelv 351 + + +Ls eA + +n + +e+ +++ + i +K+ + ++R+A+ lh++ + + ++++i++ t+ A+e v FUN_002069-T1 94 -----HASHASYTLSSEAHRILNTLNEEFIADVNEAITEGRILPKTKKI-NIILRVAASLHIFnhvttqllqqT-QptMPSEEIEKSTLLHAIEYV 182 .....4477899************9999999997777777788886666.689**********99988888641.2678888************** PP DUF3987 352 eylin 356 + ++ FUN_002069-T1 183 GWAES 187 *9876 PP >> PPP5 PPP5 TPR repeat region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 6.9e-05 0.44 36 85 .. 93 147 .. 66 155 .. 0.72 2 ? 0.3 0.0 0.18 1.1e+03 39 61 .. 180 201 .. 157 213 .. 0.69 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 6.9e-05 PPP5 36 veksYdGprL.eeee.....kitleFvkemierfkkgkklhkkyvykIllkvkell 85 +++s +L + e ++++eF+ ++ e + +g+ l+k ++I+l+v + l FUN_002069-T1 93 LHASHASYTLsS-EAhrilnTLNEEFIADVNEAITEGRILPKTKKINIILRVAASL 147 555555555631.1134454889***************************998765 PP == domain 2 score: 0.3 bits; conditional E-value: 0.18 PPP5 39 sYdGprLeeeekitleFvkemie 61 +Y G ++++i eF+ke+i FUN_002069-T1 180 EYVGWAE-SQKEIFVEFLKELIT 201 4666554.677899999999986 PP >> UNC45-central Myosin-binding striated muscle assembly central # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 0.5 3.2e+03 24 49 .. 55 80 .. 51 104 .. 0.67 2 ? 11.6 0.1 4.2e-05 0.27 13 71 .. 165 226 .. 137 230 .. 0.85 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.5 UNC45-central 24 lilsklleaakeefeeklseflksll 49 +++ k+l ++++e+e++++++ +s l FUN_002069-T1 55 ITFPKCLRPTPQETEQAVEALTQSPL 80 66667777777777777766555544 PP == domain 2 score: 11.6 bits; conditional E-value: 4.2e-05 UNC45-central 13 rqpeevrslallilskll...eaakeefeeklseflksllakgtnddlivafsalaalFpvv 71 + +ee++ ll + + e++ke f e l+e+++ l+++++++ + + +++alF ++ FUN_002069-T1 165 MPSEEIEKSTLLHAIEYVgwaESQKEIFVEFLKELITPTLDETKDQPTLLTVMTACALFGGP 226 66788888888888888899999************************************776 PP >> CENP-I Mis6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 3.2e-05 0.21 93 164 .. 124 201 .. 99 217 .. 0.79 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 3.2e-05 CENP-I 93 alkkG..la.peaidillnvalsGkfadavntrllkc...lipatvisedsvvkavswlcvgkcsgnikllflrwlia 164 a+++G l+ ++i+i+l va s ++ + v t+ll+ +p+ i ++++++a+ ++ + +i + fl+ li+ FUN_002069-T1 124 AITEGriLPkTKKINIILRVAASLHIFNHVTTQLLQQtqpTMPSEEIEKSTLLHAIEYVGWAESQKEIFVEFLKELIT 201 4444422442368**********************86222577889*************9999999999999999997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (235 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 759 (0.0297123); expected 510.9 (0.02) Passed bias filter: 648 (0.025367); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 2339.28 // Query: FUN_002070-T1 [L=188] Description: FUN_002070 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-06 27.2 0.0 5.1e-06 26.5 0.0 1.4 1 SAP SAP domain Domain annotation for each model (and alignments): >> SAP SAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.0 2e-10 5.1e-06 6 36 .. 28 58 .. 28 59 .. 0.92 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 2e-10 SAP 6 tvseLKeeLkkrGLptsGkKaeLieRLkeyl 36 tv+ LK L+ rG ++sG++++Li+R+ +y+ FUN_002070-T1 28 TVAILKRWLSCRGAKVSGNRKDLIKRVNDYI 58 56669************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 477 (0.0186729); expected 510.9 (0.02) Passed bias filter: 447 (0.0174985); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.35s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 1958.87 // Query: FUN_002072-T1 [L=87] Description: FUN_002072 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (87 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 621 (0.02431); expected 510.9 (0.02) Passed bias filter: 301 (0.0117831); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 893.72 // Query: FUN_002073-T1 [L=332] Description: FUN_002073 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.1e-09 36.0 9.5 1.2e-08 35.1 9.5 1.4 1 7tm_2 7 transmembrane receptor (Secretin family) 4.7e-08 33.3 10.7 6.3e-08 32.9 10.7 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 0.0093 15.7 18.2 0.12 12.1 14.0 2.7 2 Frizzled Frizzled/Smoothened family membrane region ------ inclusion threshold ------ 0.12 12.6 0.0 0.2 12.0 0.0 1.2 1 Abhydrolase_2 Phospholipase/Carboxylesterase Domain annotation for each model (and alignments): >> 7tm_2 7 transmembrane receptor (Secretin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.1 9.5 1.8e-12 1.2e-08 5 159 .. 26 178 .. 23 190 .. 0.83 Alignments for each domain: == domain 1 score: 35.1 bits; conditional E-value: 1.8e-12 7tm_2 5 kvittvGlslSlvaLlvalailllfrklrctrnyihlnLflslilrallvlvkdealkneedqseaeaekvgCkvvavllhYfvlanfaWllvEgl 100 +++ t + slS+v lv + ++l lr++ + i + + + ++ a++ +v+ + + +++Ck+ a+l +l++f+W + + FUN_002073-T1 26 EILCTTAASLSIVGTLVIIGTFLKWPDLRSNSRKIIVCISIGDLFVAISNVVGLYTETR----------TLVCKIQATLNIAAILSSFFWTVYLSF 111 57789999***********************9999887777778888888888877777..........9************************** PP 7tm_2 101 ylytllvevf..fserkalkkylliGwGvPalvvaiwavvd....akgylederCWlsnee..kllw 159 y+y+ + + + +se+++++++ll wG+P+++ a++ +v ++ ++ + CW++ ++ k+ w FUN_002073-T1 112 YIYMTVCRKItpQSEKRIMLFFLLTAWGIPLIIAATAYGVGavgnSDDVVSSGWCWIKYSSddKTNW 178 *****99866225679999**************9998877411124555777889998765445555 PP >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.9 10.7 9.8e-12 6.3e-08 4 214 .. 42 252 .. 39 281 .. 0.73 Alignments for each domain: == domain 1 score: 32.9 bits; conditional E-value: 9.8e-12 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 4 lVilvilrnkklrtptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykrirtk 99 ++i ++l+ lr+ + ++ ++ Dl v+ ++++++ + +++++Ck++ l ++++++s++ + +s+ Y+++++++ ++ +k FUN_002073-T1 42 VIIGTFLKWPDLRSNSRKIIVCISIGDLFVA--------ISNVVGLYTETRTLVCKIQATLNIAAILSSFFWTVYLSFYIYMTVCRKITPQS--EK 127 5666777777777777777777777777777........45555667778999*************************************76..99 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxx.xxxx.xxxxxxxxxxxxxxxxxxxxxxxxx. RF 7tm_1 100 rralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeest...wevsytlllsvl.gfll.pllvilvcyvrilrtlrksakkeks. 189 r +l+++l +W + l+++ + + + + ++++ ++ +C+i+++++++t w++++ ++++++ g+ + + i+v+y+++ + +r++ ++ FUN_002073-T1 128 RIMLFFLLTAWGIPLIIAATAYGVGAVGNSDDVVSSGWCWIKYSSDDKTnwpWQKMLFWMCMAGkGWEIlSYFAICVFYFLVKWQIRREINRGFPa 223 *********************999999888777************7777745444433333332255555****************9999887544 PP .......xxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .......kkkksarkerkalktllvvvvvfvl 214 ++ +++ + ka + l+ + vvf+l FUN_002073-T1 224 gshfltiRS-MEVVR--KADRKLMFIPVVFIL 252 444444222.22222..444444444444444 PP >> Frizzled Frizzled/Smoothened family membrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.1 14.0 1.8e-05 0.12 85 185 .. 79 182 .. 18 220 .. 0.75 2 ? -1.1 1.2 0.19 1.2e+03 47 89 .. 198 240 .. 194 282 .. 0.44 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 1.8e-05 Frizzled 85 vtegtenlsCtvvFlllYyfsmaasiWwviLtltwflaagkkwgseaiekkssyFHlvaWsiPavktivvlalkkv.dgdel..tGiCfvgnlnle 177 +++ t++l+C + l+ +++++W v L++ +++ ++k++ ++ ++ +F l aW+iP++ ++++ +++v + d + +G C + +++ + FUN_002073-T1 79 LYTETRTLVCKIQATLNIAAILSSFFWTVYLSFYIYMTVCRKITPQSEKRIMLFFLLTAWGIPLIIAATAYGVGAVgNSDDVvsSGWCWIKYSSDD 174 4566788888888889999999************************************************99999943444423799999998888 PP Frizzled 178 alrgfvla 185 ++ + FUN_002073-T1 175 KTNWPWQK 182 76654444 PP == domain 2 score: -1.1 bits; conditional E-value: 0.19 Frizzled 47 iflslCyllvsvgylirfvlgreeiackkdeekressvvtegt 89 + ++C++ + v + ir +r a ++ + r+++vv+++ FUN_002073-T1 198 SYFAICVFYFLVKWQIRREINRGFPAGSHFLTIRSMEVVRKAD 240 5666666666666666655554444444443443333333322 PP >> Abhydrolase_2 Phospholipase/Carboxylesterase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 3.1e-05 0.2 15 33 .. 276 294 .. 266 303 .. 0.84 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 3.1e-05 Abhydrolase_2 15 avviflHGlGdsghgwaea 33 + +i+lHG+Gds +g+a+ FUN_002073-T1 276 EWLILLHGVGDSSQGFANF 294 569************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (332 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1049 (0.0410648); expected 510.9 (0.02) Passed bias filter: 537 (0.0210217); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3287.73 // Query: FUN_002074-T1 [L=246] Description: FUN_002074 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0026 18.5 2.0 0.0076 17.0 2.0 1.8 1 Tad4 Type I Thoeris inhibitor Tad4 0.0064 16.9 0.3 0.0064 16.9 0.3 1.7 2 fvmX5 FtsH ternary system domain X5 ------ inclusion threshold ------ 0.04 14.6 0.7 0.04 14.6 0.7 3.4 4 FlxA FlxA-like protein 0.044 13.9 1.1 0.14 12.3 0.5 2.2 2 Nbl1_Borealin_N Nbl1 / Borealin N terminal 0.15 13.0 0.2 0.15 13.0 0.2 2.4 3 FlaC_arch Flagella accessory protein C (FlaC) 0.8 10.7 5.7 1.6 9.7 0.6 2.6 3 DUF4140 N-terminal domain of unknown function (DUF41 1.1 9.9 2.4 16 6.3 0.1 2.5 3 DUF948 Bacterial protein of unknown function (DUF94 1.1 10.2 5.8 3.8 8.5 5.8 1.9 1 CC4_CEP85 Centrosomal protein of 85 kDa-like, CC4 coil 3.7 8.1 6.4 51 4.5 0.1 3.7 4 DASH_Dad3 DASH complex subunit Dad3 5.3 7.6 4.9 1.3 9.5 0.2 2.4 3 Choline_bind_4 Choline-binding repeat 6.5 6.4 6.9 6.1 6.5 1.1 2.1 2 DUF4407 Domain of unknown function (DUF4407) Domain annotation for each model (and alignments): >> Tad4 Type I Thoeris inhibitor Tad4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 2.0 3.3e-06 0.0076 8 68 .. 166 226 .. 160 237 .. 0.87 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 3.3e-06 Tad4 8 kwakqkeknqdddeygrgfleyaekwaelmEeeiee.gkkvedaaeetleeaedkegitgfm 68 w++++ek++ ++++g++ ey kw + +E++i++ k++++++ee++ ++ ++t +m FUN_002074-T1 166 AWKENTEKQKIRQNKGKKTKEYQPKWLRQIESKIKDlRKEISQITEEVRRMR-KNGKLTTKM 226 7***********************************9999******997764.443366655 PP >> fvmX5 FtsH ternary system domain X5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.1 1.3 3.1e+03 89 98 .. 62 71 .. 12 110 .. 0.58 2 ! 16.9 0.3 2.8e-06 0.0064 112 156 .. 171 215 .. 125 224 .. 0.89 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.3 fvmX5 89 lekkreiray 98 +++r + FUN_002074-T1 62 TTTERSGTIN 71 3333333333 PP == domain 2 score: 16.9 bits; conditional E-value: 2.8e-06 fvmX5 112 qleqeLekkaekeeknlqaevtraLekklgelrkeldqvvnkvta 156 +q++ ++ k++k+ q + r++e+k+++lrke++q++++v + FUN_002074-T1 171 TEKQKIRQNKGKKTKEYQPKWLRQIESKIKDLRKEISQITEEVRR 215 45788999999******************************9976 PP >> FlxA FlxA-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.2 0.47 1.1e+03 11 28 .. 28 45 .. 18 71 .. 0.53 2 ? 0.6 0.2 0.39 9.1e+02 5 39 .. 76 110 .. 72 131 .. 0.79 3 ? -1.4 0.2 1.7 3.9e+03 73 85 .. 171 183 .. 164 193 .. 0.53 4 ? 14.6 0.7 1.7e-05 0.04 14 58 .. 194 237 .. 190 241 .. 0.80 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.47 FlxA 11 sskksesqiasLrkqikk 28 ss++ +q a+++k ++ FUN_002074-T1 28 SSHNLRDQYAKITKARSQ 45 333333333444333333 PP == domain 2 score: 0.6 bits; conditional E-value: 0.39 FlxA 5 sassassskksesqiasLrkqikkltkqlkelsds 39 +a ++ss++ +++ + L + +kk + ++ ++++ FUN_002074-T1 76 TATIEQSSNEPSEEYNTLANNAKKWYEVISRVKEK 110 67778888888889999999999999998888887 PP == domain 3 score: -1.4 bits; conditional E-value: 1.7 FlxA 73 aqkakesqqskve 85 ++k+k +q++ ++ FUN_002074-T1 171 TEKQKIRQNKGKK 183 3444333333333 PP == domain 4 score: 14.6 bits; conditional E-value: 1.7e-05 FlxA 14 ksesqiasLrkqikkltkqlkelsdsdektkeekkkqqqliqaQI 58 + es+i+ Lrk+i+++t++++ + ++ + t++ k +q ++ Q+ FUN_002074-T1 194 QIESKIKDLRKEISQITEEVRRMRKNGKLTTK-MWKNRQWMRCQL 237 689**********************9777776.345555555555 PP >> Nbl1_Borealin_N Nbl1 / Borealin N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 1.8 4.1e+03 22 37 .. 88 103 .. 87 104 .. 0.85 2 ? 12.3 0.5 5.9e-05 0.14 2 38 .. 195 234 .. 194 236 .. 0.87 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 1.8 Nbl1_Borealin_N 22 aelelllkslrnrlel 37 +e+++l++++++ +e+ FUN_002074-T1 88 EEYNTLANNAKKWYEV 103 68999***99998886 PP == domain 2 score: 12.3 bits; conditional E-value: 5.9e-05 Nbl1_Borealin_N 2 keallenfdlE...veerverlraelelllkslrnrlelr 38 +e ++++ +E ++e v+r+r++ +l++k+ +nr+ +r FUN_002074-T1 195 IESKIKDLRKEisqITEEVRRMRKNGKLTTKMWKNRQWMR 234 666688999998889********************99887 PP >> FlaC_arch Flagella accessory protein C (FlaC) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 6.9 1.6e+04 19 33 .. 25 39 .. 23 41 .. 0.59 2 ? -1.6 0.1 2.3 5.4e+03 43 48 .. 100 105 .. 75 110 .. 0.51 3 ? 13.0 0.2 6.3e-05 0.15 9 36 .. 192 219 .. 186 222 .. 0.91 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 6.9 FlaC_arch 19 lrkeneeisksveei 33 l+k+ +++++ +i FUN_002074-T1 25 LKKSSHNLRDQYAKI 39 566666666666555 PP == domain 2 score: -1.6 bits; conditional E-value: 2.3 FlaC_arch 43 lYEvVs 48 YEv+s FUN_002074-T1 100 WYEVIS 105 355555 PP == domain 3 score: 13.0 bits; conditional E-value: 6.3e-05 FlaC_arch 9 lekleseletlrkeneeisksveeieen 36 l ++es+++ lrke+++i ++v ++ +n FUN_002074-T1 192 LRQIESKIKDLRKEISQITEEVRRMRKN 219 6789******************999887 PP >> DUF4140 N-terminal domain of unknown function (DUF4140) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.1 0.083 1.9e+02 67 91 .. 20 45 .. 5 50 .. 0.81 2 ? -2.5 0.1 4.2 9.8e+03 53 53 .. 83 83 .. 62 111 .. 0.48 3 ? 9.7 0.6 0.00068 1.6 61 95 .. 174 219 .. 157 223 .. 0.69 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.083 DUF4140 67 e.lkelreeieeleaelaaledelaa 91 + ++el+++ ++l+++ a+++++++ FUN_002074-T1 20 KgYAELKKSSHNLRDQYAKITKARSQ 45 4489****************999876 PP == domain 2 score: -2.5 bits; conditional E-value: 4.2 DUF4140 53 s 53 s FUN_002074-T1 83 S 83 1 PP == domain 3 score: 9.7 bits; conditional E-value: 0.00068 DUF4140 61 eaeee..........ee.lkelreeieeleaelaaledelaaleaq 95 ++ + ++ l++++++i+ l++e++++++e +++++ FUN_002074-T1 174 QKIRQnkgkktkeyqPKwLRQIESKIKDLRKEISQITEEVRRMRKN 219 3333355556666676779******************999998876 PP >> DUF948 Bacterial protein of unknown function (DUF948) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 4.8 1.1e+04 29 47 .. 23 41 .. 19 45 .. 0.64 2 ? 2.9 0.1 0.077 1.8e+02 36 87 .. 53 107 .. 47 109 .. 0.79 3 ? 6.3 0.1 0.0069 16 28 53 .. 192 217 .. 182 228 .. 0.64 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 4.8 DUF948 29 devnktleklekqldpllk 47 +e++k+ ++l +q +++k FUN_002074-T1 23 AELKKSSHNLRDQYAKITK 41 5666666666666666665 PP == domain 2 score: 2.9 bits; conditional E-value: 0.077 DUF948 36 eklekqldpllkettella...ktnelledvneklekvdpvfeavkdlgesvskl 87 ++l q+ p+++e +++ +t ++ + ne +e+ +++ +++k++ e +s++ FUN_002074-T1 53 NELGNQTMPTTTERSGTINgdeNTATIEQSSNEPSEEYNTLANNAKKWYEVISRV 107 5788888999999888875333777889999999999999999999988888776 PP == domain 3 score: 6.3 bits; conditional E-value: 0.0069 DUF948 28 ldevnktleklekqldpllkettell 53 l+++++ +++l k++ ++++e++++ FUN_002074-T1 192 LRQIESKIKDLRKEISQITEEVRRMR 217 45555556666666666666665554 PP >> CC4_CEP85 Centrosomal protein of 85 kDa-like, CC4 coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 5.8 0.0016 3.8 3 52 .. 169 219 .. 168 239 .. 0.86 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0016 CC4_CEP85 3 eneslkk.eldrlkkviekqqkkmeqlssqiqsLeeqvaqEegtsqaLreE 52 en++ +k ++++ kk e q k + q++s+i++L ++++q + + +r++ FUN_002074-T1 169 ENTEKQKiRQNKGKKTKEYQPKWLRQIESKIKDLRKEISQITEEVRRMRKN 219 555555549999****************************98888888875 PP >> DASH_Dad3 DASH complex subunit Dad3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.1 0.022 51 12 43 .. 22 53 .. 19 57 .. 0.89 2 ? 2.1 0.0 0.12 2.9e+02 10 34 .. 88 117 .. 84 146 .. 0.76 3 ? 1.6 0.1 0.17 4e+02 29 51 .. 176 199 .. 167 203 .. 0.71 4 ? 2.4 0.1 0.096 2.2e+02 19 44 .. 192 213 .. 185 229 .. 0.57 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.022 DASH_Dad3 12 YqrLaenlkkLseelkeLsstkkgsseellde 43 Y++L+++ ++L ++ +++++++++++++ l++ FUN_002074-T1 22 YAELKKSSHNLRDQYAKITKARSQPESQFLNN 53 9********************98888887765 PP == domain 2 score: 2.1 bits; conditional E-value: 0.12 DASH_Dad3 10 eeYqrLaenlkkLseelkeLsstk.....k 34 eeY++La+n kk e ++ +++ + FUN_002074-T1 88 EEYNTLANNAKKWYEVISRVKEKNwsermS 117 69*******999999999888885554440 PP == domain 3 score: 1.6 bits; conditional E-value: 0.17 DASH_Dad3 29 Lsstk.kgsseelldeLreLErKi 51 + ++k k+++e + Lr++E Ki FUN_002074-T1 176 IRQNKgKKTKEYQPKWLRQIESKI 199 4455445556667788******98 PP == domain 4 score: 2.4 bits; conditional E-value: 0.096 DASH_Dad3 19 lkkLseelkeLsstkkgsseelldeL 44 l+++++++k+L ++ +++++e FUN_002074-T1 192 LRQIESKIKDLRKE----ISQITEEV 213 44555555555555....33333333 PP >> Choline_bind_4 Choline-binding repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.2 0.00055 1.3 2 15 .. 90 103 .. 89 103 .. 0.92 2 ? -3.7 0.1 8.5 2e+04 3 8 .. 118 123 .. 118 123 .. 0.73 3 ? -0.7 0.1 0.96 2.2e+03 16 20 .. 218 222 .. 218 223 .. 0.86 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00055 Choline_bind_4 2 yTGlvkndggWYYV 15 y++l++n WY V FUN_002074-T1 90 YNTLANNAKKWYEV 103 9***********66 PP == domain 2 score: -3.7 bits; conditional E-value: 8.5 Choline_bind_4 3 TGlvkn 8 ++++kn FUN_002074-T1 118 NTFCKN 123 678887 PP == domain 3 score: -0.7 bits; conditional E-value: 0.96 Choline_bind_4 16 kNGKv 20 kNGK+ FUN_002074-T1 218 KNGKL 222 8***8 PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.5 0.025 57 135 206 .. 21 96 .. 8 138 .. 0.69 2 ? 6.5 1.1 0.0026 6.1 111 155 .. 174 218 .. 165 235 .. 0.77 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.025 DUF4407 135 elaelqaqiaalqaeidaaekeldelqkearcelegtk....gtgttgvpGkGpeakekeeeldaaqaelaalqak 206 +ael++ +l++++++ +k++ + + ++ ++ g++ +t+ +g ++ ++e+ ++ ++e ++l ++ FUN_002074-T1 21 GYAELKKSSHNLRDQYAKITKARSQPESQFLNNELGNQtmptTTERSGTINGDENTATIEQSSNEPSEEYNTLANN 96 6899999999999999999999999998888777777776663333333333344444555555555555555444 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0026 DUF4407 111 qeldeekneeadaakaqlaqalraelaelqaqiaalqaeidaaek 155 q++ ++k +++++++ ++ ++++++++l+++i++ +e++ ++k FUN_002074-T1 174 QKIRQNKGKKTKEYQPKWLRQIESKIKDLRKEISQITEEVRRMRK 218 677777778888888888878888888888888887777776665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (246 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2939 (0.115052); expected 510.9 (0.02) Passed bias filter: 945 (0.0369935); expected 510.9 (0.02) Passed Vit filter: 118 (0.0046193); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 2384.11 // Query: FUN_002075-T1 [L=189] Description: FUN_002075 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.003 18.2 0.1 0.008 16.8 0.0 1.7 2 PG_binding_4 Putative peptidoglycan binding domain Domain annotation for each model (and alignments): >> PG_binding_4 Putative peptidoglycan binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 0.27 6.8e+03 52 52 .. 43 43 .. 15 71 .. 0.56 2 ! 16.8 0.0 3.1e-07 0.008 72 104 .. 122 154 .. 120 161 .. 0.90 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.27 PG_binding_4 52 y 52 + FUN_002075-T1 43 V 43 2 PP == domain 2 score: 16.8 bits; conditional E-value: 3.1e-07 PG_binding_4 72 pkdAslklsggtvtvipekkGrkvdveklledi 104 p+d +++++++ +++++++Grk+d++++++ + FUN_002075-T1 122 PRDEIFVFEEEQKKIKEHHYGRKIDISATIDLF 154 89999***********************98765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (189 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 622 (0.0243492); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.43s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 1835.03 // Query: FUN_002076-T1 [L=358] Description: FUN_002076 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.7e-09 36.0 15.2 7.9e-09 35.6 15.2 1.3 1 Dicty_CAR Slime mold cyclic AMP receptor 2.5e-08 34.0 14.1 3.6e-08 33.4 14.1 1.4 1 7tm_2 7 transmembrane receptor (Secretin family) 0.00015 21.6 20.4 0.0066 16.2 20.6 2.1 1 Frizzled Frizzled/Smoothened family membrane region Domain annotation for each model (and alignments): >> Dicty_CAR Slime mold cyclic AMP receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.6 15.2 9.3e-13 7.9e-09 13 176 .. 33 203 .. 20 306 .. 0.84 Alignments for each domain: == domain 1 score: 35.6 bits; conditional E-value: 9.3e-13 Dicty_CAR 13 vllladfssilgcllvligfwrlkllrnhitkvialfcatsllkdlistiltlleeaqesgfpcylyaivitygslacwlwtlclalsiynlivkr 108 + f s++g+++++++f +r ++i ++ ++ + + t+ +++s + c l a+ l+ +lwt+ l+l y+ i k+ FUN_002076-T1 33 LSTTVAFLSMVGAVIIVVTFIVYPDIRTNSRRIIVYISISDFSVACLNTVGLYNPATSDSKLTCKLQATLTVVAVLSSFLWTVNLSLYFYMTICKK 128 44456799*******************************9999999888766666777789*********************************99 PP Dicty_CAR 109 epe..pekfekyyfvlcwglplistivmlskevi....e.vvgnwcwigekyvgyrfglfygpfliiwaisavlv 176 +++ ++v wg+p+ +++ + + + v +wcwi+ + ++ l+ + w isa +v FUN_002076-T1 129 ISTaaEKRMMTLFHVTAWGFPITIAVFAYGLQGVgytrDmVSSGWCWISTDKPWWQVVLWMSLTGKAWEISAYIV 203 654114678999**********9999988776662222213468******9999999999998888899988665 PP >> 7tm_2 7 transmembrane receptor (Secretin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.4 14.1 4.3e-12 3.6e-08 6 165 .. 32 189 .. 27 290 .. 0.78 Alignments for each domain: == domain 1 score: 33.4 bits; conditional E-value: 4.3e-12 7tm_2 6 vittvGlslSlvaLlvalailllfrklrctrnyihlnLflslilrallvlvkdealkneedqseaeaekvgCkvvavllhYfvlanfaWllvEgly 101 ++ t lS+v ++ ++++++ +r + + i + + +s + a l v+ + + + +k+ Ck+ a+l+ vl++f+W + ly FUN_002076-T1 32 ILSTTVAFLSMVGAVIIVVTFIVYPDIRTNSRRIIVYISISDFSVACLNTVGLYNPAT-------SDSKLTCKLQATLTVVAVLSSFLWTVNLSLY 120 677888899*********************9999999999999999998888877777.......6789*************************** PP 7tm_2 102 lytllvevffs..erkalkkylliGwGvPalvvaiwavvd....akgylederCWlsneekllwiikgPv 165 y+ + + +++ e++++ +++ wG+P+++ + + +++ ++ ++ + CW+s++++ +w + + FUN_002076-T1 121 FYMTICKKISTaaEKRMMTLFHVTAWGFPITIAVFAYGLQgvgyTRDMVSSGWCWISTDKP-WWQVVLWM 189 *****987765226899999************999998862222444577789******98.55554444 PP >> Frizzled Frizzled/Smoothened family membrane region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 20.6 7.8e-07 0.0066 6 177 .. 26 182 .. 22 220 .. 0.77 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 7.8e-07 Frizzled 6 ekkfaelwiallailclvstlftvlTFlidterfrYPerpiiflslCyllvsvgylirfvlgreeiackkdeekressvvtegtenlsCtvvFlll 101 + ++ +++ +++a+l++v +++ v+TF++ ++ r+i+++s++ + v++ ++++ a + ++l+C + l+ FUN_002076-T1 26 HTSVNRILSTTVAFLSMVGAVIIVVTFIVYPDIRTNSRRIIVYISISDFSVACLNTVGLYNP----A-TS-------------DSKLTCKLQATLT 103 556677889999*******************99999***********999999888888764....1.11.............2467888888888 PP Frizzled 102 YyfsmaasiWwviLtltwflaagkkwgseaiekkssyFHlvaWsiPavktivvlalkkv..dgdel.tGiCfvgnlnle 177 +++++W v L+l ++++ +kk++ a ++ ++FH+ aW++P+ ++++ l+ v d + +G C ++ + FUN_002076-T1 104 VVAVLSSFLWTVNLSLYFYMTICKKISTAAEKRMMTLFHVTAWGFPITIAVFAYGLQGVgyTRDMVsSGWCWISTDKPW 182 88999*****************************************999888877776622234432466666666555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (358 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1007 (0.0394206); expected 510.9 (0.02) Passed bias filter: 414 (0.0162067); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.35u 0.37s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3474.21 // Query: FUN_002079-T1 [L=286] Description: FUN_002079 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-18 66.3 7.9 1.5e-05 25.1 0.8 3.5 3 TPR_1 Tetratricopeptide repeat 1.2e-13 50.5 6.8 0.00067 20.1 0.2 3.5 3 TPR_2 Tetratricopeptide repeat 5.3e-07 29.7 0.4 0.018 15.2 0.0 3.5 3 TPR_11 TPR repeat 8.5e-07 29.1 6.1 0.15 12.8 0.1 4.2 4 TPR_8 Tetratricopeptide repeat 1.9e-06 28.4 0.6 0.057 14.1 0.0 2.5 2 TPR_12 Tetratricopeptide repeat 4.3e-06 27.1 4.5 0.00035 20.9 1.9 2.3 2 TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR re 5.5e-05 23.9 0.4 0.00045 21.0 0.2 2.3 2 TPR_19 Tetratricopeptide repeat 0.00011 22.7 0.2 0.29 12.0 0.0 3.1 2 TPR_17 Tetratricopeptide repeat 0.00019 22.3 1.3 0.22 12.8 0.6 3.3 3 TPR_14 Tetratricopeptide repeat 0.0021 18.6 1.3 0.046 14.3 1.3 2.6 2 TPR_9 Tetratricopeptide repeat 0.005 17.8 0.2 0.071 14.1 0.0 2.3 2 TPR_16 Tetratricopeptide repeat 0.0065 16.9 0.3 1.9 9.1 0.2 3.1 3 TPR_10 Tetratricopeptide repeat ------ inclusion threshold ------ 0.017 15.9 3.8 0.16 12.7 0.6 2.5 2 ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 0.031 15.4 1.3 1.4 10.2 0.1 3.3 3 TPR_6 Tetratricopeptide repeat 0.048 14.0 6.5 0.035 14.5 3.0 2.1 2 ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal AR 0.05 14.5 0.2 0.69 10.8 0.1 2.3 2 TPR_Slam Surface lipoprotein assembly modifier, N-terminal Domain annotation for each model (and alignments): >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 0.8 9.2e-09 1.5e-05 1 34 [] 116 149 .. 116 149 .. 0.95 2 ! 23.9 0.2 2.2e-08 3.5e-05 3 34 .] 157 188 .. 155 188 .. 0.93 3 ! 20.4 0.1 2.9e-07 0.00046 5 28 .. 193 216 .. 190 222 .. 0.87 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 9.2e-09 TPR_1 1 akalynlGnayfklgkydeAleyyekALelnPnn 34 a+ ++ +Gn yfk +y eA e+y A++++P++ FUN_002079-T1 116 AQEYKEKGNDYFKRSEYLEAKEFYTNAIKICPDD 149 67899***************************96 PP == domain 2 score: 23.9 bits; conditional E-value: 2.2e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALelnPnn 34 + n+++++ k y+eA++++ kAL n ++ FUN_002079-T1 157 FHANRAACLVKIDHYKEAIDDCTKALDFNSDY 188 689*************************9886 PP == domain 3 score: 20.4 bits; conditional E-value: 2.9e-07 TPR_1 5 ynlGnayfklgkydeAleyyekAL 28 +++++y + +++eAle+y+k+ FUN_002079-T1 193 LRRAQCYEHEDRLEEALEDYQKVF 216 69********************86 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.2 4.2e-07 0.00067 2 34 .] 117 149 .. 116 149 .. 0.93 2 ! 16.4 0.1 6.4e-06 0.01 3 33 .. 157 187 .. 155 188 .. 0.90 3 ! 16.4 0.2 6.4e-06 0.01 6 28 .. 194 216 .. 190 221 .. 0.89 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 4.2e-07 TPR_2 2 ealynlGlayyklgdyeeAleayekAleldPnn 34 + + + G+ y+k+ +y eA+e+y A++++P++ FUN_002079-T1 117 QEYKEKGNDYFKRSEYLEAKEFYTNAIKICPDD 149 678899*************************96 PP == domain 2 score: 16.4 bits; conditional E-value: 6.4e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleldPn 33 + n++ ++ k +y+eA++++ kAl + + FUN_002079-T1 157 FHANRAACLVKIDHYKEAIDDCTKALDFNSD 187 799***********************98865 PP == domain 3 score: 16.4 bits; conditional E-value: 6.4e-06 TPR_2 6 nlGlayyklgdyeeAleayekAl 28 +++++y++ ++eeAle+y+k+ FUN_002079-T1 194 RRAQCYEHEDRLEEALEDYQKVF 216 89******************986 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 1.1e-05 0.018 1 27 [. 123 149 .. 123 150 .. 0.97 2 ? 4.1 0.0 0.034 54 10 37 .. 171 198 .. 166 201 .. 0.80 3 ! 6.4 0.0 0.0063 10 9 21 .. 204 216 .. 202 222 .. 0.83 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.1e-05 TPR_11 1 GdayyeqGkyeeAieaYkkAlkldPdn 27 G+ y+++ +y eA e Y +A+k++Pd+ FUN_002079-T1 123 GNDYFKRSEYLEAKEFYTNAIKICPDD 149 9*************************8 PP == domain 2 score: 4.1 bits; conditional E-value: 0.034 TPR_11 10 yeeAieaYkkAlkldPdnaeayynLGla 37 y+eAi + kAl++++d+ + + +++ FUN_002079-T1 171 YKEAIDDCTKALDFNSDYMKVRLRRAQC 198 8889999999999999998877777665 PP == domain 3 score: 6.4 bits; conditional E-value: 0.0063 TPR_11 9 kyeeAieaYkkAl 21 ++eeA+e+Y+k FUN_002079-T1 204 RLEEALEDYQKVF 216 79********975 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 4.6 7.3e+03 7 16 .. 115 124 .. 114 126 .. 0.82 2 ! 9.1 0.2 0.0014 2.2 15 34 .] 130 149 .. 121 149 .. 0.85 3 ! 7.7 0.1 0.004 6.3 5 33 .. 159 187 .. 155 188 .. 0.87 4 ! 12.8 0.1 9.3e-05 0.15 4 31 .. 192 219 .. 190 220 .. 0.89 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 4.6 TPR_8 7 lGliylklgd 16 +++ y+++g+ FUN_002079-T1 115 KAQEYKEKGN 124 7889999987 PP == domain 2 score: 9.1 bits; conditional E-value: 0.0014 TPR_8 15 gdyeeAkeyyekaleldpdn 34 +y eAke+y a+++ pd+ FUN_002079-T1 130 SEYLEAKEFYTNAIKICPDD 149 5788**************86 PP == domain 3 score: 7.7 bits; conditional E-value: 0.004 TPR_8 5 ynlGliylklgdyeeAkeyyekaleldpd 33 n++ ++ k y+eA+ + kal+ + d FUN_002079-T1 159 ANRAACLVKIDHYKEAIDDCTKALDFNSD 187 5778889999**************98876 PP == domain 4 score: 12.8 bits; conditional E-value: 9.3e-05 TPR_8 4 yynlGliylklgdyeeAkeyyekaleld 31 ++++++y+ ++eeA e y+k+ ++d FUN_002079-T1 192 RLRRAQCYEHEDRLEEALEDYQKVFDAD 219 5789*******************98765 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 3.5e-05 0.057 9 73 .. 122 183 .. 114 186 .. 0.91 2 ! 12.2 0.2 0.00014 0.22 7 32 .. 193 218 .. 187 228 .. 0.85 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 3.5e-05 TPR_12 9 lAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqale 73 ++ ++++ +y eA e++ +a+ ++ +++ + a+ + n + ++ + +y+eA++ +al+ FUN_002079-T1 122 KGNDYFKRSEYLEAKEFYTNAIKIC---PDDFVKEKAIFHANRAACLVKIDHYKEAIDDCTKALD 183 7999*********************...8888999**********************98777776 PP == domain 2 score: 12.2 bits; conditional E-value: 0.00014 TPR_12 7 nnlAavlrrlgrydeAlellekalel 32 ++ A+++ + +r++eAle ++k+ ++ FUN_002079-T1 193 LRRAQCYEHEDRLEEALEDYQKVFDA 218 5799*****************99876 PP >> TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 1.9 2.2e-07 0.00035 22 110 .. 97 188 .. 87 191 .. 0.81 2 ! 7.0 0.1 0.0046 7.3 78 107 .. 190 219 .. 185 227 .. 0.81 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 2.2e-07 TPR_BSK1_C 22 ddegvanelsfqmwtqqmqetlnskkkgDaaFrakdfktaiecytqfidag....tmvsptvyarrslsylmsdkpqeALkdamqaqvispew 110 +de+ ++ l+ ++ + ++ + k kg F++ ++ +a e+yt+ i+ + ++ +a r+ + + d+ +eA++d+++a +++++ FUN_002079-T1 97 KDEE-QETLTSEEKEDRKAKAQEYKEKGNDYFKRSEYLEAKEFYTNAIKICpddfVKEKAIFHANRAACLVKIDHYKEAIDDCTKALDFNSDY 188 4444.4667778888899999***************************87633213455566799*********************9988776 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0046 TPR_BSK1_C 78 tvyarrslsylmsdkpqeALkdamqaqvis 107 v rr+ +y d+ +eAL+d +++ FUN_002079-T1 190 KVRLRRAQCYEHEDRLEEALEDYQKVFDAD 219 6778******************88876555 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.77 1.2e+03 4 23 .. 129 148 .. 126 168 .. 0.84 2 ! 21.0 0.2 2.8e-07 0.00045 7 56 .. 171 220 .. 165 232 .. 0.87 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.77 TPR_19 4 egdydeAlalLeqalaedPd 23 +y eA++++++a+++ Pd FUN_002079-T1 129 RSEYLEAKEFYTNAIKICPD 148 567999********998777 PP == domain 2 score: 21.0 bits; conditional E-value: 2.8e-07 TPR_19 7 ydeAlalLeqalaedPdnaearllLArallalgrldeAealLaalpaadp 56 y+eA+ +++al+ + d+ +rl+ A+++ + +rl+eA + +++ +ad+ FUN_002079-T1 171 YKEAIDDCTKALDFNSDYMKVRLRRAQCYEHEDRLEEALEDYQKVFDADH 220 99************************************986666666665 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0053 8.4 1 33 [. 138 175 .. 138 176 .. 0.91 2 ! 12.0 0.0 0.00018 0.29 2 34 .] 178 210 .. 178 210 .. 0.96 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0053 TPR_17 1 lylkaleldPnn.....adayynLArlllnnGqleeAl 33 +y+ a++++P++ a ++ n+A +l + +++ eA+ FUN_002079-T1 138 FYTNAIKICPDDfvkekAIFHANRAACLVKIDHYKEAI 175 6999********9999999999*****99999999997 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00018 TPR_17 2 ylkaleldPnnadayynLArlllnnGqleeAlq 34 ++kal+ + ++ ++ +A+++++ ++leeAl+ FUN_002079-T1 178 CTKALDFNSDYMKVRLRRAQCYEHEDRLEEALE 210 78*****************************85 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.035 56 4 34 .. 119 149 .. 116 152 .. 0.86 2 ? 5.0 0.0 0.045 73 7 43 .. 161 197 .. 157 198 .. 0.91 3 ! 12.8 0.6 0.00014 0.22 3 44 .] 191 232 .. 189 232 .. 0.93 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.035 TPR_14 4 wlalarallalGdpdeAlelleralaldPdd 34 ++ ++ ++++ ++ eA e + a++ +Pdd FUN_002079-T1 119 YKEKGNDYFKRSEYLEAKEFYTNAIKICPDD 149 566677788999999***************8 PP == domain 2 score: 5.0 bits; conditional E-value: 0.045 TPR_14 7 larallalGdpdeAlelleralaldPddpeawlalar 43 +a+ l++ ++++eA++ +al + d+ ++l++a+ FUN_002079-T1 161 RAACLVKIDHYKEAIDDCTKALDFNSDYMKVRLRRAQ 197 78899999***************99999*****9998 PP == domain 3 score: 12.8 bits; conditional E-value: 0.00014 TPR_14 3 awlalarallalGdpdeAlelleralaldPddpeawlalarl 44 ++l++a+ ++ ++++eAle +++ +d +++ a++al rl FUN_002079-T1 191 VRLRRAQCYEHEDRLEEALEDYQKVFDADHSSHVAREALMRL 232 5799*******************************9999875 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.4 6.3e+02 29 62 .. 116 149 .. 114 155 .. 0.90 2 ! 14.3 1.3 2.9e-05 0.046 9 72 .. 169 232 .. 162 233 .. 0.90 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.4 TPR_9 29 peerrdrGllyaqlgcleaAladLeaylalapda 62 + e+ ++G y+++ + +A + +++++pd+ FUN_002079-T1 116 AQEYKEKGNDYFKRSEYLEAKEFYTNAIKICPDD 149 6799999999**********************97 PP == domain 2 score: 14.3 bits; conditional E-value: 2.9e-05 TPR_9 9 edleralavverllllaPddpeerrdrGllyaqlgcleaAladLeaylalapdapdaeairell 72 +++ +a+ + l ++ d r r+++y++ ++le+Al+d ++ + + +++ a+++ ++l FUN_002079-T1 169 DHYKEAIDDCTKALDFNSDYMKVRLRRAQCYEHEDRLEEALEDYQKVFDADHSSHVAREALMRL 232 788899999999999999999999***************************9999999998887 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.091 1.4e+02 3 59 .. 122 183 .. 120 188 .. 0.77 2 ! 14.1 0.0 4.4e-05 0.071 12 57 .. 170 215 .. 165 222 .. 0.85 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.091 TPR_16 3 laraalaagdyddAaaaleaalrrn.....PeaaaAllglGlallrqgrlaeAaaayraalr 59 ++++++++ +y +A + +++a++ e a ++ +++ +l + + eA++ + +al+ FUN_002079-T1 122 KGNDYFKRSEYLEAKEFYTNAIKICpddfvKEKAIFHANRAACLVKIDHYKEAIDDCTKALD 183 68889999999999988888888555556777888888888888888888888888888876 PP == domain 2 score: 14.1 bits; conditional E-value: 4.4e-05 TPR_16 12 dyddAaaaleaalrrnPeaaaAllglGlallrqgrlaeAaaayraa 57 +y +A+ + al+ n + + +l++++++++ rl+eA++ y++ FUN_002079-T1 170 HYKEAIDDCTKALDFNSDYMKVRLRRAQCYEHEDRLEEALEDYQKV 215 678888888888998999999*******************999875 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.073 1.2e+02 9 32 .. 123 146 .. 122 146 .. 0.93 2 ? -0.0 0.0 0.89 1.4e+03 17 29 .. 170 182 .. 165 186 .. 0.58 3 ! 9.1 0.2 0.0012 1.9 23 40 .. 203 220 .. 194 222 .. 0.86 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.073 TPR_10 9 analraqgryeeAeelleealair 32 +n ++++ +y eA e++ a++i+ FUN_002079-T1 123 GNDYFKRSEYLEAKEFYTNAIKIC 146 799**************9999986 PP == domain 2 score: -0.0 bits; conditional E-value: 0.89 TPR_10 17 ryeeAeelleeal 29 y+eA +++ +al FUN_002079-T1 170 HYKEAIDDCTKAL 182 3555555555554 PP == domain 3 score: 9.1 bits; conditional E-value: 0.0012 TPR_10 23 elleealairervlGpdH 40 + leeal+ +++v+ +dH FUN_002079-T1 203 DRLEEALEDYQKVFDADH 220 5589*************9 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.6 0.0001 0.16 30 77 .. 123 176 .. 106 181 .. 0.82 2 ? 3.5 0.2 0.077 1.2e+02 30 59 .. 196 226 .. 178 232 .. 0.77 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.0001 ANAPC3 30 AqclflngqykrAyellrka.klneksl..gcryllA...qcllkLkkykeAld 77 ++ +f++++y +A e+ +a k+ + + + ++ +A cl+k+++ykeA+d FUN_002079-T1 123 GNDYFKRSEYLEAKEFYTNAiKICPDDFvkEKAIFHAnraACLVKIDHYKEAID 176 6789****************999998889844444444559999********97 PP == domain 2 score: 3.5 bits; conditional E-value: 0.077 ANAPC3 30 AqclflngqykrAyellrka.klnekslgcr 59 Aqc+ ++ + ++A+e +k + +++s +r FUN_002079-T1 196 AQCYEHEDRLEEALEDYQKVfDADHSSHVAR 226 9999999999999999999977777776655 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.31 5e+02 10 32 .. 126 148 .. 122 149 .. 0.85 2 ? -2.0 0.0 6.8 1.1e+04 7 24 .. 162 179 .. 160 183 .. 0.71 3 ? 10.2 0.1 0.00089 1.4 3 26 .. 192 215 .. 190 218 .. 0.91 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.31 TPR_6 10 ylelgdkdeAkaalqrlikkYPd 32 y++ ++ eAk+++ ik Pd FUN_002079-T1 126 YFKRSEYLEAKEFYTNAIKICPD 148 77767899**********99997 PP == domain 2 score: -2.0 bits; conditional E-value: 6.8 TPR_6 7 alsylelgdkdeAkaalq 24 a ++ + + ++eA++ FUN_002079-T1 162 AACLVKIDHYKEAIDDCT 179 678888888889987655 PP == domain 3 score: 10.2 bits; conditional E-value: 0.00089 TPR_6 3 llklalsylelgdkdeAkaalqrl 26 l+ a++y+ ++ +eA++ +q++ FUN_002079-T1 192 RLRRAQCYEHEDRLEEALEDYQKV 215 699*******99**********98 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 3.0 2.2e-05 0.035 128 201 .. 113 192 .. 86 197 .. 0.71 2 ? 0.3 0.1 0.48 7.7e+02 138 163 .. 198 223 .. 194 232 .. 0.70 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 2.2e-05 ARM_TT21_C 128 cakAyel..lGliaekeqsykdAaenYekAWkl....skesspavGykLAfnyLKakryveaidvcqkvLkvkPdypkir 201 akA e+ G + k+++y +A e Y +A k+ ++++ A +++K +y eaid c+k L + dy k+r FUN_002079-T1 113 KAKAQEYkeKGNDYFKRSEYLEAKEFYTNAIKIcpddFVKEKAIFHANRAACLVKIDHYKEAIDDCTKALDFNSDYMKVR 192 3455555226888999****************94433122333333456999**************************98 PP == domain 2 score: 0.3 bits; conditional E-value: 0.48 ARM_TT21_C 138 iaekeqsykdAaenYekAWklskess 163 ++e+e++ ++A e Y+k ++ ++s+ FUN_002079-T1 198 CYEHEDRLEEALEDYQKVFDADHSSH 223 56777777777777777776666554 PP >> TPR_Slam Surface lipoprotein assembly modifier, N-terminal TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.00043 0.69 46 101 .. 154 209 .. 147 212 .. 0.87 2 ? 6.2 0.1 0.012 19 54 84 .. 196 226 .. 195 232 .. 0.87 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00043 TPR_Slam 46 eiLlkyaqAilarsqgnyaeAialYrellaekpdllpvrlqlAqaLfenkqneaAk 101 + + + +A+ + + +y+eAi+ + l+ ++d vrl+ Aq + + + e+A FUN_002079-T1 154 KAIFHANRAACLVKIDHYKEAIDDCTKALDFNSDYMKVRLRRAQCYEHEDRLEEAL 209 5566667788888899****************************999999988885 PP == domain 2 score: 6.2 bits; conditional E-value: 0.012 TPR_Slam 54 AilarsqgnyaeAialYrellaekpdllpvr 84 A +++ +++eA + Y+++++++ + +++r FUN_002079-T1 196 AQCYEHEDRLEEALEDYQKVFDADHSSHVAR 226 66778999****************9999988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (286 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2072 (0.0811118); expected 510.9 (0.02) Passed bias filter: 622 (0.0243492); expected 510.9 (0.02) Passed Vit filter: 67 (0.00262282); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 2742.75 // Query: FUN_002080-T1 [L=879] Description: FUN_002080 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-95 319.7 0.0 2.3e-95 319.3 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 4.5e-43 148.0 0.0 6.7e-43 147.4 0.0 1.2 1 Pkinase Protein kinase domain 4.9e-40 136.4 0.5 4.3e-13 50.0 0.0 4.5 3 Ig_3 Immunoglobulin domain 1.1e-35 122.0 0.1 3e-12 46.9 0.0 4.4 4 I-set Immunoglobulin I-set domain 2.2e-28 98.9 0.1 8.2e-10 39.3 0.0 3.9 3 ig Immunoglobulin domain 3.3e-23 82.2 2.2 2.6e-08 34.5 0.0 4.2 3 Ig_2 Immunoglobulin domain 8.3e-17 61.8 0.8 8e-05 23.3 0.0 5.5 3 V-set Immunoglobulin V-set domain 0.005 17.3 0.0 0.25 11.8 0.0 3.1 3 C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C ------ inclusion threshold ------ 0.01 16.4 2.4 0.55 10.8 0.0 3.7 4 C2-set_2 CD80-like C2-set immunoglobulin domain 0.038 14.3 0.2 0.083 13.2 0.2 1.5 1 DUF5337 Family of unknown function (DUF5337) 0.038 13.6 0.0 0.085 12.5 0.0 1.5 1 ABC1 ABC1 atypical kinase-like domain 0.057 13.7 0.5 7.6 6.9 0.1 3.5 3 Adeno_E3_CR1 Adenovirus E3 region protein CR1 0.22 11.3 0.0 0.36 10.5 0.0 1.2 1 Kinase-like Kinase-like 0.23 11.9 1.0 33 5.0 0.4 2.6 2 Syndecan Syndecan domain 0.65 11.1 3.0 12 7.1 0.1 3.8 4 Ig_4 T-cell surface glycoprotein CD3 delta chain Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 319.3 0.0 1.3e-98 2.3e-95 2 257 .. 493 756 .. 492 757 .. 0.98 Alignments for each domain: == domain 1 score: 319.3 bits; conditional E-value: 1.3e-98 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlke.ekekkkikVavKtlkeeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrk 94 ++ lGeGafG+V+k+++ + + k +VavK+lke+a+++e +++++e+++mk++ +h+ni++l+g+ct+++pl++v+ey+++G+L++fLr+ FUN_002080-T1 493 NFVGVLGEGAFGRVMKAEIIGlPSMPFKFNVAVKMLKEDATDHELADLVSEMEVMKTIgKHKNIINLIGACTQGGPLYVVVEYASNGNLRQFLRE 587 56778***************97778889******************************************************************* PP PK_Tyr_Ser-Thr 95 k......keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkfts 183 + +++l+l +l+++ +q+ +GmeyL+ kk++HrdlaarN+Lv e+++ ki+DfGLard+++ dyy+k+++++lp+kWma+E+l ++++t+ FUN_002080-T1 588 RrptkeySTTLTLVDLVSFGYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQVDYYRKTTDGRLPVKWMALEALFDRVYTT 682 *****9999************************************************************************************** PP PK_Tyr_Ser-Thr 184 ksDvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelvee 257 +sDvW+fG+llwEi+t+g +py+g+ e+++ell+ g+r+++p ncp+++ye+m +Cw+e+p++Rptf+elv+e FUN_002080-T1 683 QSDVWAFGILLWEIVTFGGSPYPGVPIENLFELLKLGYRMDKPINCPNNMYEIMLKCWQESPSKRPTFTELVKE 756 ***********************************************************************987 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 147.4 0.0 4e-46 6.7e-43 4 258 .. 495 755 .. 492 757 .. 0.86 Alignments for each domain: == domain 1 score: 147.4 bits; conditional E-value: 4e-46 Pkinase 4 leklGeGsfgkVykav.....eketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdllsrkg 93 + lGeG+fg+V+ka + + vA+K++k++ ++++ ++++E++++k++ h+ni++li+++++ ly+v+Ey+++g+l ++l++++ FUN_002080-T1 495 VGVLGEGAFGRVMKAEiiglpSMPFKFNVAVKMLKEDATDHEL-ADLVSEMEVMKTIGkHKNIINLIGACTQGGPLYVVVEYASNGNLRQFLRERR 589 5689********9986222223345668*******99888866.69***********99**********************************666 PP Pkinase 94 alsee.......eakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk...ltsfvgtseYmAPEvlkskkygkkvD 179 +e ++ ++ +q+++g+eyl ++++HrDl NiL+ e+++lKi+DFGla+ +++ +t+ ++mA E l ++ y++++D FUN_002080-T1 590 PTKEYsttltlvDLVSFGYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQVDYyrkTTDGRLPVKWMALEALFDRVYTTQSD 685 666666666666999***********************************************9987776678888889****************** PP Pkinase 180 vWslGvilyellt.gkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellq 258 vW+ G++l+e++t g +p+++ +++l+++lk+ +++p ++ +++ +++ k++++ p+kR+t++el++ FUN_002080-T1 686 VWAFGILLWEIVTfGGSPYPGVP--------IENLFELLKL--GYRMDKPINCPNNMYEIMLKCWQESPSKRPTFTELVK 755 **********9864899***333........3443444444..467888999*************************987 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.0 0.0 2.5e-16 4.3e-13 2 78 .] 24 103 .. 23 103 .. 0.93 2 ! 44.3 0.0 1.5e-14 2.6e-11 13 78 .] 148 214 .. 132 214 .. 0.83 3 ! 35.6 0.1 8e-12 1.4e-08 1 78 [] 234 339 .. 234 339 .. 0.83 Alignments for each domain: == domain 1 score: 50.0 bits; conditional E-value: 2.5e-16 Ig_3 2 PvitvspsstvveegesvtLtCea....egnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P+i+++ + t v ege+++L C++ +++++p + W kn+++l++ s+ + ++ + ++ L+i++v++ed+G YtCvA+N FUN_002080-T1 24 PKIRTKGNITLVPEGEEARLICSVndkgTSGNKPIVFWEKNNETLQPASHNR-MRIKPYRYLKIKRVSKEDAGFYTCVAEN 103 99**9999999***************999999***********977766654.99*************************9 PP == domain 2 score: 44.3 bits; conditional E-value: 1.5e-14 Ig_3 13 veegesvtLtCeaegnppptitWykngkelssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 + +g+s+++ C+a+g+p+pt+ Wyk+ ++ + + + + ++ ++i+++ + dsG YtC +sN FUN_002080-T1 148 IPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGG-SklHIGMFQTLVIIRDAVPADSGIYTCNVSN 214 789*************************84443333.2478999999999*****************9 PP == domain 3 score: 35.6 bits; conditional E-value: 8e-12 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskr...............................sssssnstLtisn 63 kP++ + t ++ege++tL C+a +++ p+++W++ ++s + + + ++ +L++ n FUN_002080-T1 234 KPKVLKMENAT-AVEGENATLLCKALSDSMPHFQWLRWLASpsNTS--N--QsseienpvyevikqneqngnkqlllpnghtsKLDFHGVKLILVN 324 67777555555.7************************999753222..2..2235799********999999999999999988888888999999 PP Ig_3 64 vtredsGtYtCvAsN 78 vt++d+G+Y+C++ N FUN_002080-T1 325 VTKKDEGKYSCIVGN 339 ************987 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.9 0.0 1.7e-15 3e-12 1 88 [. 24 114 .. 24 116 .. 0.87 2 ! 46.0 0.0 3.5e-15 5.9e-12 10 87 .. 146 224 .. 140 227 .. 0.84 3 ! 8.4 0.0 0.0018 3.1 6 37 .. 239 270 .. 236 289 .. 0.85 4 ! 15.2 0.0 1.3e-05 0.023 49 85 .. 313 347 .. 297 352 .. 0.78 Alignments for each domain: == domain 1 score: 46.9 bits; conditional E-value: 1.7e-15 I-set 1 pkftqklkdvevkeGesaeleckvsGe....pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeL 88 pk+ +k + + v eGe+a+l c+v + +p v W k+++ l++ ++ +++ + L+I++v+keD+G Ytc+a+ns g++ + +L FUN_002080-T1 24 PKIRTKGNITLVPEGEEARLICSVNDKgtsgNKPIVFWEKNNETLQPASHNRMRIKP-YRYLKIKRVSKEDAGFYTCVAENSCGRKAITWRL 114 5666677777899***********755335569**********************99.778***********************99888776 PP == domain 2 score: 46.0 bits; conditional E-value: 3.5e-15 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee.gtatLtIsnvkkeDeGkYtckatnsageaeasae 87 +++ +G+s +++c+++G p+p+v W+kd+ ++e k + + + ++ +I+++ ++D+G+Ytc+++n +g + s + FUN_002080-T1 146 IAIPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGGSKLHIGmFQTLVIIRDAVPADSGIYTCNVSNAYGWINNSYK 224 57889****************************9666665555535577789******************997666655 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0018 I-set 6 klkdvevkeGesaeleckvsGepepevsWlkd 37 k++++++ eGe+a+l ck+ + p+++Wl+ FUN_002080-T1 239 KMENATAVEGENATLLCKALSDSMPHFQWLRW 270 678999***********************975 PP == domain 4 score: 15.2 bits; conditional E-value: 1.3e-05 I-set 49 vkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 +++ + +L++ nv+k+DeGkY+c + n +g a ++ FUN_002080-T1 313 LDFHG--VKLILVNVTKKDEGKYSCIVGNAIGYAVQQ 347 44444..8999*******************9987665 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.3 0.0 4.8e-13 8.2e-10 4 74 .. 34 105 .. 33 111 .. 0.93 2 ! 31.1 0.0 1.8e-10 3.1e-07 4 73 .. 147 215 .. 145 220 .. 0.91 3 ! 23.4 0.1 4.6e-08 7.9e-05 4 75 .. 244 342 .. 241 345 .. 0.77 Alignments for each domain: == domain 1 score: 39.3 bits; conditional E-value: 4.8e-13 ig 4 tvleGesatLtCsas...egspgpdvtWskegktkieslkvkedngrttqs...sllisnvteedaGtYtCvvnnpg 74 +v+eGe a+L Cs++ ++ p+v+W+k+++t++ ++ +r+++ l i +v++edaG+YtCv++n+ FUN_002080-T1 34 LVPEGEEARLICSVNdkgTSGNKPIVFWEKNNETLQPASH-----NRMRIKpyrYLKIKRVSKEDAGFYTCVAENSC 105 799*************9999999*****************.....99999988889******************985 PP == domain 2 score: 31.1 bits; conditional E-value: 1.8e-10 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++G+s+++ Csa+ g p p+v+W k++ +e + +++q+ + i+++ + d+G YtC v+n+ FUN_002080-T1 147 AIPVGNSFRMDCSAT-GYPKPTVIWYKDKALFQERKGGSKLHIGMFQTLVIIRDAVPADSGIYTCNVSNA 215 5789***********.*************99999988666667889**********************97 PP == domain 3 score: 23.4 bits; conditional E-value: 4.6e-08 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslk............vkedngrttqs..................sllisnvteedaGtYtCv 69 t+ eGe+atL C+a +++ p+++W + ++ +++ + +++ + ++ l ++nvt++d+G Y+C FUN_002080-T1 244 TAVEGENATLLCKAL-SDSMPHFQWLRWLASPSNTSNqsseienpvyevI--KQNEQNGNkqlllpnghtskldfhgvKLILVNVTKKDEGKYSCI 336 6679***********.*********8754444333333466988888531..333333335789******************************** PP ig 70 vnnpgg 75 v n+ g FUN_002080-T1 337 VGNAIG 342 988765 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.5 0.0 6.3e-11 1.1e-07 3 66 .. 25 104 .. 23 111 .. 0.78 2 ! 34.5 0.0 1.5e-11 2.6e-08 10 72 .. 147 220 .. 135 227 .. 0.81 3 ! 11.2 0.2 0.00027 0.47 3 65 .. 237 339 .. 234 351 .. 0.73 Alignments for each domain: == domain 1 score: 32.5 bits; conditional E-value: 6.3e-11 Ig_2 3 vltasp..tvvtegesvtLtCsas.....gnppakytwykdgkvls.ssqn........fft.snvsaedsGtYtCtarnt 66 +++ t v+ege+ +L Cs+ gn ++ + w k+++ l+ s+n ++ ++vs ed+G YtC+a+n+ FUN_002080-T1 25 KIRTKGniTLVPEGEEARLICSVNdkgtsGN-KPIVFWEKNNETLQpASHNrmrikpyrYLKiKRVSKEDAGFYTCVAENS 104 55543344779*************8887444.67799*****99996466678899887443599*************996 PP == domain 2 score: 34.5 bits; conditional E-value: 1.5e-11 Ig_2 10 vvtegesvtLtCsasgnppakytwykdgkvlsssqn............fftsnvsaedsGtYtCtarntkggkvs 72 ++ g s+++ Csa g p++++ wykd +++++ ++++ + + dsG+YtC ++n g + FUN_002080-T1 147 AIPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGgsklhigmfqtlVIIRDAVPADSGIYTCNVSNAY-GWIN 220 5789************************9999666666888898777666799***************54.4444 PP == domain 3 score: 11.2 bits; conditional E-value: 0.00027 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdg..................kvls.ssqn.....................fftsnvsaedsGt 58 vl ++ + ege+ tL C+a ++ + ++w + +v++ + qn +++ nv+ d G FUN_002080-T1 237 VLKMENATAVEGENATLLCKALSDSMPHFQWLRWLaspsntsnqsseienpvyEVIKqNEQNgnkqlllpnghtskldfhgvkLILVNVTKKDEGK 332 5677778899**********99887788888876666778888998888888855554223344775655555566666666444466******** PP Ig_2 59 YtCtarn 65 Y+C ++n FUN_002080-T1 333 YSCIVGN 339 *****99 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.3 0.0 0.00012 0.21 72 98 .. 81 106 .. 31 116 .. 0.66 2 ! 13.2 0.0 6.3e-05 0.11 72 96 .. 192 216 .. 144 228 .. 0.63 3 ! 23.3 0.0 4.7e-08 8e-05 7 95 .. 244 341 .. 240 352 .. 0.74 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00012 V-set 72 dfsltiqnltlsDsGtYtCavipkgev 98 l+i+ ++ +D+G+YtC+ +++++ FUN_002080-T1 81 YRYLKIKRVSKEDAGFYTCV-AENSCG 106 5579***************9.565555 PP == domain 2 score: 13.2 bits; conditional E-value: 6.3e-05 V-set 72 dfsltiqnltlsDsGtYtCavipkg 96 + i+++ ++DsG+YtC+v + + FUN_002080-T1 192 QTLVIIRDAVPADSGIYTCNVSNAY 216 45679***************84443 PP == domain 3 score: 23.3 bits; conditional E-value: 4.7e-08 V-set 7 tvaeGesvtLtCslssseseasqsvyWyrqppgk.....epteliayysnkseeekkkgrfslrkdpsrsdfs...ltiqnltlsDsGtYtCav.i 93 t++eGe++tL C+ s + + q+++W p+++ e + ++ +++e++ +k+ ++++s+ df+ l + n+t +D+G Y C v + FUN_002080-T1 244 TAVEGENATLLCKALSDSMPHFQWLRWLASPSNTsnqssEIENPVYEVIKQNEQNGNKQLLLPNGHTSKLDFHgvkLILVNVTKKDEGKYSCIVgN 339 899*********88888778***********998654443333444444466666667777777777777764444****************9754 PP V-set 94 pk 95 + FUN_002080-T1 340 AI 341 44 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.66 1.1e+03 29 80 .. 56 104 .. 24 108 .. 0.64 2 ! 11.8 0.0 0.00015 0.25 16 79 .. 153 214 .. 146 217 .. 0.77 3 ? -0.2 0.0 0.84 1.4e+03 62 80 .. 322 340 .. 296 343 .. 0.77 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.66 C2-set_3 29 ePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnp 80 +P v W++++ +l+++s++ + ++ ++ v+++ + ++C+ +n+ FUN_002080-T1 56 KPIVFWEKNNE-TLQPASHNRMRI--KPYRYLKIKRVSKEDAGFYTCVAENS 104 68888987766.666666644433..34555555556666667777777765 PP == domain 2 score: 11.8 bits; conditional E-value: 0.00015 C2-set_3 16 girlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvre...ssnknvsCsirn 79 r+ C+++G yP+P+v W++ k l ++ + s+ + g+f++ +++r+ + ++ ++C ++n FUN_002080-T1 153 SFRMDCSATG-YPKPTVIWYKDKA--LFQERKGGSKLHIGMFQT--LVIIRDavpADSGIYTCNVSN 214 5689998887.********98876..888888889999999976..566666444556778888888 PP == domain 3 score: -0.2 bits; conditional E-value: 0.84 C2-set_3 62 slvvressnknvsCsirnp 80 + v+++ ++++sC++ n FUN_002080-T1 322 LVNVTKKDEGKYSCIVGNA 340 456889999*******996 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.17 2.9e+02 12 45 .. 37 72 .. 25 102 .. 0.70 2 ? 0.6 0.1 0.5 8.5e+02 20 36 .. 98 114 .. 84 139 .. 0.84 3 ? 10.8 0.0 0.00032 0.55 15 39 .. 152 175 .. 132 190 .. 0.81 4 ? -2.4 0.0 4.3 7.3e+03 11 48 .. 247 282 .. 239 291 .. 0.54 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.17 C2-set_2 12 aeekevvatCv....saggkPapritWlldgkeleaae 45 ++e + C+ ++g+ +p + W++++++l+ a+ FUN_002080-T1 37 E-GEEARLICSvndkGTSGN-KPIVFWEKNNETLQPAS 72 2.478888999777645555.47889999999983333 PP == domain 2 score: 0.6 bits; conditional E-value: 0.5 C2-set_2 20 tCvsaggkPapritWll 36 tCv++++ + itW l FUN_002080-T1 98 TCVAENSCGRKAITWRL 114 9**************86 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00032 C2-set_2 15 kevvatCvsaggkPapritWlldgk 39 + ++C sa g+P+p++ W++d FUN_002080-T1 152 NSFRMDC-SATGYPKPTVIWYKDKA 175 5677899.99***********9965 PP == domain 4 score: -2.4 bits; conditional E-value: 4.3 C2-set_2 11 eaeekevvatCvsaggkPapritWlldgkel.eaaetss 48 e+e + ++ C a + p+ +Wl+ + +++++ss FUN_002080-T1 247 EGE--NATLLC-KALSDSMPHFQWLRWLASPsNTSNQSS 282 444..666667.444444457777766655422344443 PP >> DUF5337 Family of unknown function (DUF5337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.2 4.9e-05 0.083 36 71 .. 379 414 .. 374 416 .. 0.93 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 4.9e-05 DUF5337 36 qlGlpaRfalLfdLaAlAaliwalvvtyqiwraRqn 71 + G + + ++++ +a++ ++++a +v + ++r+R++ FUN_002080-T1 379 ATGTSSKAKVFISFAVVLGFVFAAIVGLLVYRHRRR 414 7899******************************97 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 5e-05 0.085 184 220 .. 617 653 .. 595 661 .. 0.87 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 5e-05 ABC1 184 ifedgffhaDphpGNllvrkdgelvllDfGlmgelde 220 + ++++h D+ + N+lv ++++l + DfGl +++++ FUN_002080-T1 617 LSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQ 653 667899***************************9965 PP >> Adeno_E3_CR1 Adenovirus E3 region protein CR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.98 1.7e+03 62 83 .. 84 105 .. 52 117 .. 0.82 2 ? 2.0 0.0 0.14 2.5e+02 17 37 .. 157 174 .. 142 229 .. 0.72 3 ? 6.9 0.1 0.0044 7.6 59 78 .. 317 336 .. 293 347 .. 0.84 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.98 Adeno_E3_CR1 62 LtLlnvtktyeGtYygtnkkss 83 L + v+k++ G+Y + ++s FUN_002080-T1 84 LKIKRVSKEDAGFYTCVAENSC 105 566789999*****99988874 PP == domain 2 score: 2.0 bits; conditional E-value: 0.14 Adeno_E3_CR1 17 nltLvGpsegkVtWykleedg 37 +++ +G+++ V+Wy +d+ FUN_002080-T1 157 DCSATGYPKPTVIWY---KDK 174 78889**********...333 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0044 Adeno_E3_CR1 59 kqnLtLlnvtktyeGtYygt 78 + L+L+nvtk++eG Y + FUN_002080-T1 317 GVKLILVNVTKKDEGKYSCI 336 678**************986 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.00021 0.36 151 246 .. 607 698 .. 576 718 .. 0.87 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00021 Kinase-like 151 TlqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvv..sevekgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysi 244 q++r +L k +h ++ ++n+l e+ +++ +f+ L r+ ++v +++ g P ++ ++ + r t + d+W+ G+ ++ i FUN_002080-T1 607 GYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFG-LARDIHQVDyyRKTTDGRLPVKWMALEAL-FDR----VYTTQSDVWAFGILLWEI 696 569************************************7.8999988887789999999*999999777.877....788899*******99988 PP Kinase-like 245 wc 246 FUN_002080-T1 697 VT 698 76 PP >> Syndecan Syndecan domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.03 50 28 43 .. 319 334 .. 317 340 .. 0.85 2 ? 5.0 0.4 0.019 33 15 36 .. 393 413 .. 384 415 .. 0.80 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.03 Syndecan 28 lllvYrmrKKDEGsYa 43 l++ + KKDEG Y+ FUN_002080-T1 319 KLILVNVTKKDEGKYS 334 57777889*******6 PP == domain 2 score: 5.0 bits; conditional E-value: 0.019 Syndecan 15 GvvvgllfavllvlllvYrmrK 36 vv+g++fa +v llvYr r+ FUN_002080-T1 393 AVVLGFVFAA-IVGLLVYRHRR 413 6788999986.789*****886 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.1 0.0068 12 15 50 .. 59 102 .. 39 111 .. 0.73 2 ? 1.0 0.0 0.52 8.9e+02 40 49 .. 203 214 .. 158 231 .. 0.72 3 ? -0.6 0.0 1.7 3e+03 31 48 .. 319 336 .. 295 349 .. 0.76 4 ? -2.3 0.2 5.8 9.8e+03 16 40 .. 838 863 .. 833 866 .. 0.73 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0068 Ig_4 15 itwlkdgkeikeskek........tldlgksiedprglYqCkee 50 + w k++++ + ++++ l+++++++++ g Y+C e FUN_002080-T1 59 VFWEKNNETLQPASHNrmrikpyrYLKIKRVSKEDAGFYTCVAE 102 567777777666665555666666899**************853 PP == domain 2 score: 1.0 bits; conditional E-value: 0.52 Ig_4 40 dprglYqCk..e 49 ++g+Y+C+ + FUN_002080-T1 203 ADSGIYTCNvsN 214 578999998431 PP == domain 3 score: -0.6 bits; conditional E-value: 1.7 Ig_4 31 tldlgksiedprglYqCk 48 +l l ++++ ++g Y+C FUN_002080-T1 319 KLILVNVTKKDEGKYSCI 336 78888999999******6 PP == domain 4 score: -2.3 bits; conditional E-value: 5.8 Ig_4 16 twlkdgkeikeskek.tldlgksied 40 wl+ + +i++++++ + +lg+ ++ FUN_002080-T1 838 VWLESERQIERRHSRrKSNLGEAENN 863 68888888887776669999988776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (879 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 729 (0.0285379); expected 510.9 (0.02) Passed bias filter: 679 (0.0265805); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.44u 0.39s 00:00:00.83 Elapsed: 00:00:00.43 # Mc/sec: 8150.54 // Query: FUN_002080-T2 [L=732] Description: FUN_002080 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-82 277.6 0.0 1.6e-82 277.2 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 2.3e-40 137.4 0.5 3.3e-13 50.4 0.0 4.4 3 Ig_3 Immunoglobulin domain 2.3e-38 132.6 0.0 3.7e-38 131.9 0.0 1.3 1 Pkinase Protein kinase domain 4.6e-36 123.2 0.1 2.3e-12 47.3 0.0 4.3 4 I-set Immunoglobulin I-set domain 9.9e-29 100.0 0.1 6.5e-10 39.7 0.0 4.0 3 ig Immunoglobulin domain 1.4e-23 83.4 2.1 2e-08 34.8 0.0 4.2 3 Ig_2 Immunoglobulin domain 3.2e-17 63.2 0.8 6.1e-05 23.7 0.0 5.4 4 V-set Immunoglobulin V-set domain 0.0029 18.0 0.0 0.2 12.2 0.0 3.2 3 C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C 0.0046 17.5 2.2 0.44 11.1 0.0 3.8 4 C2-set_2 CD80-like C2-set immunoglobulin domain ------ inclusion threshold ------ 0.026 14.8 0.3 6 7.2 0.1 3.7 4 Adeno_E3_CR1 Adenovirus E3 region protein CR1 0.029 14.7 0.2 0.067 13.5 0.2 1.5 1 DUF5337 Family of unknown function (DUF5337) 0.034 13.8 0.0 0.069 12.8 0.0 1.4 1 ABC1 ABC1 atypical kinase-like domain 0.14 13.2 0.7 9.3 7.4 0.1 3.4 3 Ig_4 T-cell surface glycoprotein CD3 delta chain 0.15 12.5 1.0 27 5.3 0.4 2.6 2 Syndecan Syndecan domain 0.17 12.4 0.0 1 9.9 0.0 2.4 2 Ig_C17orf99 C17orf99 Ig domain 0.17 11.6 0.0 0.29 10.8 0.0 1.2 1 Kinase-like Kinase-like 0.2 12.1 0.1 2.6 8.5 0.0 2.7 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-li Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 277.2 0.0 1e-85 1.6e-82 2 233 .. 493 732 .] 492 732 .] 0.98 Alignments for each domain: == domain 1 score: 277.2 bits; conditional E-value: 1e-85 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlke.ekekkkikVavKtlkeeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrk 94 ++ lGeGafG+V+k+++ + + k +VavK+lke+a+++e +++++e+++mk++ +h+ni++l+g+ct+++pl++v+ey+++G+L++fLr+ FUN_002080-T2 493 NFVGVLGEGAFGRVMKAEIIGlPSMPFKFNVAVKMLKEDATDHELADLVSEMEVMKTIgKHKNIINLIGACTQGGPLYVVVEYASNGNLRQFLRE 587 56778***************97778889******************************************************************* PP PK_Tyr_Ser-Thr 95 k......keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkfts 183 + +++l+l +l+++ +q+ +GmeyL+ kk++HrdlaarN+Lv e+++ ki+DfGLard+++ dyy+k+++++lp+kWma+E+l ++++t+ FUN_002080-T2 588 RrptkeySTTLTLVDLVSFGYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQVDYYRKTTDGRLPVKWMALEALFDRVYTT 682 *****9999************************************************************************************** PP PK_Tyr_Ser-Thr 184 ksDvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeel 233 +sDvW+fG+llwEi+t+g +py+g+ e+++ell+ g+r+++p ncp+++ FUN_002080-T2 683 QSDVWAFGILLWEIVTFGGSPYPGVPIENLFELLKLGYRMDKPINCPNNM 732 ***********************************************975 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.4 0.0 2.2e-16 3.3e-13 2 78 .] 24 103 .. 23 103 .. 0.93 2 ! 44.6 0.0 1.4e-14 2.1e-11 13 78 .] 148 214 .. 132 214 .. 0.83 3 ! 36.0 0.1 7e-12 1e-08 1 78 [] 234 339 .. 234 339 .. 0.83 Alignments for each domain: == domain 1 score: 50.4 bits; conditional E-value: 2.2e-16 Ig_3 2 PvitvspsstvveegesvtLtCea....egnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P+i+++ + t v ege+++L C++ +++++p + W kn+++l++ s+ + ++ + ++ L+i++v++ed+G YtCvA+N FUN_002080-T2 24 PKIRTKGNITLVPEGEEARLICSVndkgTSGNKPIVFWEKNNETLQPASHNR-MRIKPYRYLKIKRVSKEDAGFYTCVAEN 103 99**9999999***************999999***********977766654.99*************************9 PP == domain 2 score: 44.6 bits; conditional E-value: 1.4e-14 Ig_3 13 veegesvtLtCeaegnppptitWykngkelssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 + +g+s+++ C+a+g+p+pt+ Wyk+ ++ + + + + ++ ++i+++ + dsG YtC +sN FUN_002080-T2 148 IPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGG-SklHIGMFQTLVIIRDAVPADSGIYTCNVSN 214 789*************************84443333.2478999999999*****************9 PP == domain 3 score: 36.0 bits; conditional E-value: 7e-12 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskr...............................sssssnstLtisn 63 kP++ + t ++ege++tL C+a +++ p+++W++ ++s + + + ++ +L++ n FUN_002080-T2 234 KPKVLKMENAT-AVEGENATLLCKALSDSMPHFQWLRWLASpsNTS--N--QsseienpvyevikqneqngnkqlllpnghtsKLDFHGVKLILVN 324 67777555555.7************************999753222..2..2235799********999999999999999988888888999999 PP Ig_3 64 vtredsGtYtCvAsN 78 vt++d+G+Y+C++ N FUN_002080-T2 325 VTKKDEGKYSCIVGN 339 ************987 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 131.9 0.0 2.4e-41 3.7e-38 4 198 .. 495 705 .. 492 720 .. 0.87 Alignments for each domain: == domain 1 score: 131.9 bits; conditional E-value: 2.4e-41 Pkinase 4 leklGeGsfgkVykav.....eketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdllsrkg 93 + lGeG+fg+V+ka + + vA+K++k++ ++++ ++++E++++k++ h+ni++li+++++ ly+v+Ey+++g+l ++l++++ FUN_002080-T2 495 VGVLGEGAFGRVMKAEiiglpSMPFKFNVAVKMLKEDATDHEL-ADLVSEMEVMKTIGkHKNIINLIGACTQGGPLYVVVEYASNGNLRQFLRERR 589 5689********9986222223345668*******99888866.69***********99**********************************666 PP Pkinase 94 alsee.......eakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk...ltsfvgtseYmAPEvlkskkygkkvD 179 +e ++ ++ +q+++g+eyl ++++HrDl NiL+ e+++lKi+DFGla+ +++ +t+ ++mA E l ++ y++++D FUN_002080-T2 590 PTKEYsttltlvDLVSFGYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQVDYyrkTTDGRLPVKWMALEALFDRVYTTQSD 685 666666666666999***********************************************9987776678888889****************** PP Pkinase 180 vWslGvilyellt.gkppfs 198 vW+ G++l+e++t g +p++ FUN_002080-T2 686 VWAFGILLWEIVTfGGSPYP 705 **********9863556665 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.3 0.0 1.5e-15 2.3e-12 1 88 [. 24 114 .. 24 116 .. 0.87 2 ! 46.3 0.0 3.1e-15 4.6e-12 10 87 .. 146 224 .. 140 227 .. 0.84 3 ! 8.7 0.0 0.0017 2.5 6 37 .. 239 270 .. 236 289 .. 0.85 4 ! 15.5 0.0 1.2e-05 0.018 49 85 .. 313 347 .. 297 352 .. 0.78 Alignments for each domain: == domain 1 score: 47.3 bits; conditional E-value: 1.5e-15 I-set 1 pkftqklkdvevkeGesaeleckvsGe....pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeL 88 pk+ +k + + v eGe+a+l c+v + +p v W k+++ l++ ++ +++ + L+I++v+keD+G Ytc+a+ns g++ + +L FUN_002080-T2 24 PKIRTKGNITLVPEGEEARLICSVNDKgtsgNKPIVFWEKNNETLQPASHNRMRIKP-YRYLKIKRVSKEDAGFYTCVAENSCGRKAITWRL 114 5666777777899***********755335569**********************99.778***********************99888776 PP == domain 2 score: 46.3 bits; conditional E-value: 3.1e-15 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee.gtatLtIsnvkkeDeGkYtckatnsageaeasae 87 +++ +G+s +++c+++G p+p+v W+kd+ ++e k + + + ++ +I+++ ++D+G+Ytc+++n +g + s + FUN_002080-T2 146 IAIPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGGSKLHIGmFQTLVIIRDAVPADSGIYTCNVSNAYGWINNSYK 224 57889****************************9666665555535577789******************997666655 PP == domain 3 score: 8.7 bits; conditional E-value: 0.0017 I-set 6 klkdvevkeGesaeleckvsGepepevsWlkd 37 k++++++ eGe+a+l ck+ + p+++Wl+ FUN_002080-T2 239 KMENATAVEGENATLLCKALSDSMPHFQWLRW 270 678999***********************975 PP == domain 4 score: 15.5 bits; conditional E-value: 1.2e-05 I-set 49 vkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 +++ + +L++ nv+k+DeGkY+c + n +g a ++ FUN_002080-T2 313 LDFHG--VKLILVNVTKKDEGKYSCIVGNAIGYAVQQ 347 44444..8999*******************9987665 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.7 0.0 4.3e-13 6.5e-10 4 74 .. 34 105 .. 33 111 .. 0.93 2 ! 31.4 0.0 1.6e-10 2.5e-07 4 73 .. 147 215 .. 145 220 .. 0.91 3 ! 23.7 0.1 4.1e-08 6.1e-05 4 75 .. 244 342 .. 241 345 .. 0.77 Alignments for each domain: == domain 1 score: 39.7 bits; conditional E-value: 4.3e-13 ig 4 tvleGesatLtCsas...egspgpdvtWskegktkieslkvkedngrttqs...sllisnvteedaGtYtCvvnnpg 74 +v+eGe a+L Cs++ ++ p+v+W+k+++t++ ++ +r+++ l i +v++edaG+YtCv++n+ FUN_002080-T2 34 LVPEGEEARLICSVNdkgTSGNKPIVFWEKNNETLQPASH-----NRMRIKpyrYLKIKRVSKEDAGFYTCVAENSC 105 799*************9999999*****************.....99999988889******************985 PP == domain 2 score: 31.4 bits; conditional E-value: 1.6e-10 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++G+s+++ Csa+ g p p+v+W k++ +e + +++q+ + i+++ + d+G YtC v+n+ FUN_002080-T2 147 AIPVGNSFRMDCSAT-GYPKPTVIWYKDKALFQERKGGSKLHIGMFQTLVIIRDAVPADSGIYTCNVSNA 215 5789***********.*************99999988666667889**********************97 PP == domain 3 score: 23.7 bits; conditional E-value: 4.1e-08 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslk............vkedngrttqs..................sllisnvteedaGtYtCv 69 t+ eGe+atL C+a +++ p+++W + ++ +++ + +++ + ++ l ++nvt++d+G Y+C FUN_002080-T2 244 TAVEGENATLLCKAL-SDSMPHFQWLRWLASPSNTSNqsseienpvyevI--KQNEQNGNkqlllpnghtskldfhgvKLILVNVTKKDEGKYSCI 336 6679***********.*********8754444333333466988888531..333333335789******************************** PP ig 70 vnnpgg 75 v n+ g FUN_002080-T2 337 VGNAIG 342 988765 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.8 0.0 5.6e-11 8.4e-08 3 66 .. 25 104 .. 23 111 .. 0.78 2 ! 34.8 0.0 1.4e-11 2e-08 10 72 .. 147 220 .. 135 227 .. 0.81 3 ! 11.6 0.2 0.00024 0.35 3 65 .. 237 339 .. 234 351 .. 0.73 Alignments for each domain: == domain 1 score: 32.8 bits; conditional E-value: 5.6e-11 Ig_2 3 vltasp..tvvtegesvtLtCsas.....gnppakytwykdgkvls.ssqn........fft.snvsaedsGtYtCtarnt 66 +++ t v+ege+ +L Cs+ gn ++ + w k+++ l+ s+n ++ ++vs ed+G YtC+a+n+ FUN_002080-T2 25 KIRTKGniTLVPEGEEARLICSVNdkgtsGN-KPIVFWEKNNETLQpASHNrmrikpyrYLKiKRVSKEDAGFYTCVAENS 104 55543344779*************8887444.67799*****99996466678899887443599*************996 PP == domain 2 score: 34.8 bits; conditional E-value: 1.4e-11 Ig_2 10 vvtegesvtLtCsasgnppakytwykdgkvlsssqn............fftsnvsaedsGtYtCtarntkggkvs 72 ++ g s+++ Csa g p++++ wykd +++++ ++++ + + dsG+YtC ++n g + FUN_002080-T2 147 AIPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGgsklhigmfqtlVIIRDAVPADSGIYTCNVSNAY-GWIN 220 5789************************9999666666888898777666799***************54.4444 PP == domain 3 score: 11.6 bits; conditional E-value: 0.00024 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdg..................kvls.ssqn.....................fftsnvsaedsGt 58 vl ++ + ege+ tL C+a ++ + ++w + +v++ + qn +++ nv+ d G FUN_002080-T2 237 VLKMENATAVEGENATLLCKALSDSMPHFQWLRWLaspsntsnqsseienpvyEVIKqNEQNgnkqlllpnghtskldfhgvkLILVNVTKKDEGK 332 5677778899**********99887788888876666778888998888888855554223344775655555566666666444466******** PP Ig_2 59 YtCtarn 65 Y+C ++n FUN_002080-T2 333 YSCIVGN 339 *****99 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.024 36 7 39 .. 34 67 .. 29 73 .. 0.89 2 ! 11.2 0.0 0.0003 0.45 74 98 .. 83 106 .. 71 116 .. 0.83 3 ! 13.5 0.0 5.7e-05 0.085 72 96 .. 192 216 .. 144 228 .. 0.63 4 ! 23.7 0.0 4.1e-08 6.1e-05 7 95 .. 244 341 .. 240 352 .. 0.74 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.024 V-set 7 tvaeGesvtLtCslsss.eseasqsvyWyrqppg 39 v+eGe ++L Cs++++ +s + v W + ++ FUN_002080-T2 34 LVPEGEEARLICSVNDKgTSGNKPIVFWEKNNET 67 699************9999999999***998865 PP == domain 2 score: 11.2 bits; conditional E-value: 0.0003 V-set 74 sltiqnltlsDsGtYtCavipkgev 98 l+i+ ++ +D+G+YtC+ +++++ FUN_002080-T2 83 YLKIKRVSKEDAGFYTCV-AENSCG 106 599**************9.566555 PP == domain 3 score: 13.5 bits; conditional E-value: 5.7e-05 V-set 72 dfsltiqnltlsDsGtYtCavipkg 96 + i+++ ++DsG+YtC+v + + FUN_002080-T2 192 QTLVIIRDAVPADSGIYTCNVSNAY 216 45679***************84443 PP == domain 4 score: 23.7 bits; conditional E-value: 4.1e-08 V-set 7 tvaeGesvtLtCslssseseasqsvyWyrqppgk.....epteliayysnkseeekkkgrfslrkdpsrsdfs...ltiqnltlsDsGtYtCav.i 93 t++eGe++tL C+ s + + q+++W p+++ e + ++ +++e++ +k+ ++++s+ df+ l + n+t +D+G Y C v + FUN_002080-T2 244 TAVEGENATLLCKALSDSMPHFQWLRWLASPSNTsnqssEIENPVYEVIKQNEQNGNKQLLLPNGHTSKLDFHgvkLILVNVTKKDEGKYSCIVgN 339 899*********88888778***********998654443333444444466666667777777777777764444****************9754 PP V-set 94 pk 95 + FUN_002080-T2 340 AI 341 44 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.58 8.7e+02 29 80 .. 56 104 .. 23 108 .. 0.65 2 ! 12.2 0.0 0.00013 0.2 16 79 .. 153 214 .. 146 217 .. 0.77 3 ? 0.1 0.0 0.75 1.1e+03 62 80 .. 322 340 .. 295 343 .. 0.76 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.58 C2-set_3 29 ePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnp 80 +P v W++++ +l+++s++ + ++ ++ v+++ + ++C+ +n+ FUN_002080-T2 56 KPIVFWEKNNE-TLQPASHNRMRI--KPYRYLKIKRVSKEDAGFYTCVAENS 104 78888987766.666666644433..34555555566666667777777765 PP == domain 2 score: 12.2 bits; conditional E-value: 0.00013 C2-set_3 16 girlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvre...ssnknvsCsirn 79 r+ C+++G yP+P+v W++ k l ++ + s+ + g+f++ +++r+ + ++ ++C ++n FUN_002080-T2 153 SFRMDCSATG-YPKPTVIWYKDKA--LFQERKGGSKLHIGMFQT--LVIIRDavpADSGIYTCNVSN 214 5689998887.********98876..888888889999999976..566666444556778888888 PP == domain 3 score: 0.1 bits; conditional E-value: 0.75 C2-set_3 62 slvvressnknvsCsirnp 80 + v+++ ++++sC++ n FUN_002080-T2 322 LVNVTKKDEGKYSCIVGNA 340 456889999*******996 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.15 2.3e+02 12 45 .. 37 72 .. 25 102 .. 0.70 2 ? 0.9 0.1 0.46 6.9e+02 20 36 .. 98 114 .. 84 139 .. 0.84 3 ! 11.1 0.0 0.0003 0.44 15 39 .. 152 175 .. 132 190 .. 0.81 4 ? -2.0 0.0 3.7 5.6e+03 10 48 .. 246 282 .. 239 292 .. 0.55 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.15 C2-set_2 12 aeekevvatCv....saggkPapritWlldgkeleaae 45 ++e + C+ ++g+ +p + W++++++l+ a+ FUN_002080-T2 37 E-GEEARLICSvndkGTSGN-KPIVFWEKNNETLQPAS 72 2.478888999777645555.47889999999983333 PP == domain 2 score: 0.9 bits; conditional E-value: 0.46 C2-set_2 20 tCvsaggkPapritWll 36 tCv++++ + itW l FUN_002080-T2 98 TCVAENSCGRKAITWRL 114 9**************86 PP == domain 3 score: 11.1 bits; conditional E-value: 0.0003 C2-set_2 15 kevvatCvsaggkPapritWlldgk 39 + ++C sa g+P+p++ W++d FUN_002080-T2 152 NSFRMDC-SATGYPKPTVIWYKDKA 175 5677899.99***********9965 PP == domain 4 score: -2.0 bits; conditional E-value: 3.7 C2-set_2 10 leaeekevvatCvsaggkPapritWlldgkel.eaaetss 48 +e+e + ++ C a + p+ +Wl+ + +++++ss FUN_002080-T2 246 VEGE--NATLLC-KALSDSMPHFQWLRWLASPsNTSNQSS 282 4444..666667.444444557777766655422333333 PP >> Adeno_E3_CR1 Adenovirus E3 region protein CR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.86 1.3e+03 62 83 .. 84 105 .. 51 117 .. 0.81 2 ? 2.4 0.0 0.13 2e+02 17 37 .. 157 174 .. 142 229 .. 0.72 3 ? -3.6 0.0 9.6 1.4e+04 8 21 .. 241 254 .. 238 266 .. 0.82 4 ? 7.2 0.1 0.004 6 59 78 .. 317 336 .. 293 348 .. 0.84 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.86 Adeno_E3_CR1 62 LtLlnvtktyeGtYygtnkkss 83 L + v+k++ G+Y + ++s FUN_002080-T2 84 LKIKRVSKEDAGFYTCVAENSC 105 567789999*****99988874 PP == domain 2 score: 2.4 bits; conditional E-value: 0.13 Adeno_E3_CR1 17 nltLvGpsegkVtWykleedg 37 +++ +G+++ V+Wy +d+ FUN_002080-T2 157 DCSATGYPKPTVIWY---KDK 174 78889**********...333 PP == domain 3 score: -3.6 bits; conditional E-value: 9.6 Adeno_E3_CR1 8 knvtvtvgsnltLv 21 +n t+ g+n+tL FUN_002080-T2 241 ENATAVEGENATLL 254 67788899999985 PP == domain 4 score: 7.2 bits; conditional E-value: 0.004 Adeno_E3_CR1 59 kqnLtLlnvtktyeGtYygt 78 + L+L+nvtk++eG Y + FUN_002080-T2 317 GVKLILVNVTKKDEGKYSCI 336 678**************986 PP >> DUF5337 Family of unknown function (DUF5337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.2 4.4e-05 0.067 36 71 .. 379 414 .. 374 416 .. 0.93 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 4.4e-05 DUF5337 36 qlGlpaRfalLfdLaAlAaliwalvvtyqiwraRqn 71 + G + + ++++ +a++ ++++a +v + ++r+R++ FUN_002080-T2 379 ATGTSSKAKVFISFAVVLGFVFAAIVGLLVYRHRRR 414 7899******************************97 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 4.6e-05 0.069 184 220 .. 617 653 .. 595 661 .. 0.87 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 4.6e-05 ABC1 184 ifedgffhaDphpGNllvrkdgelvllDfGlmgelde 220 + ++++h D+ + N+lv ++++l + DfGl +++++ FUN_002080-T2 617 LSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQ 653 667899***************************9965 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.1 0.0062 9.3 15 50 .. 59 102 .. 39 111 .. 0.73 2 ? 1.4 0.0 0.47 7.1e+02 40 49 .. 203 214 .. 157 231 .. 0.72 3 ? -0.3 0.0 1.6 2.4e+03 31 48 .. 319 336 .. 295 349 .. 0.76 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0062 Ig_4 15 itwlkdgkeikeskek........tldlgksiedprglYqCkee 50 + w k++++ + ++++ l+++++++++ g Y+C e FUN_002080-T2 59 VFWEKNNETLQPASHNrmrikpyrYLKIKRVSKEDAGFYTCVAE 102 567777777666665555666666899**************853 PP == domain 2 score: 1.4 bits; conditional E-value: 0.47 Ig_4 40 dprglYqCk..e 49 ++g+Y+C+ + FUN_002080-T2 203 ADSGIYTCNvsN 214 578999998431 PP == domain 3 score: -0.3 bits; conditional E-value: 1.6 Ig_4 31 tldlgksiedprglYqCk 48 +l l ++++ ++g Y+C FUN_002080-T2 319 KLILVNVTKKDEGKYSCI 336 78889999999******6 PP >> Syndecan Syndecan domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.027 41 28 43 .. 319 334 .. 317 340 .. 0.85 2 ? 5.3 0.4 0.018 27 15 36 .. 393 413 .. 384 415 .. 0.80 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.027 Syndecan 28 lllvYrmrKKDEGsYa 43 l++ + KKDEG Y+ FUN_002080-T2 319 KLILVNVTKKDEGKYS 334 57777899*******6 PP == domain 2 score: 5.3 bits; conditional E-value: 0.018 Syndecan 15 GvvvgllfavllvlllvYrmrK 36 vv+g++fa +v llvYr r+ FUN_002080-T2 393 AVVLGFVFAA-IVGLLVYRHRR 413 6788999986.789*****886 PP >> Ig_C17orf99 C17orf99 Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.00069 1 13 90 .. 35 115 .. 23 119 .. 0.74 2 ? -3.3 0.0 9.2 1.4e+04 16 31 .. 248 263 .. 242 265 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00069 Ig_C17orf99 13 fpksrrvlisCha....segspPItYsLvgkkgivvakkivkegkPAnFsllitlkssPdlltyaCqAantsgvqasslvLq 90 +p+++ + + C ++g +PI++ +++ a + kP ++ l+i s+ d y+C+A+n+ g +a + +L+ FUN_002080-T2 35 VPEGEEARLICSVndkgTSGNKPIVFWEKNNETLQPASHNRMRIKPYRY-LKIKRVSKEDAGFYTCVAENSCGRKAITWRLV 115 6777777777765222257899999875555555555555556668876.99*********************999888886 PP == domain 2 score: -3.3 bits; conditional E-value: 9.2 Ig_C17orf99 16 srrvlisChasegspP 31 ++ ++++C+a + s P FUN_002080-T2 248 GENATLLCKALSDSMP 263 6778999999999988 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00019 0.29 151 246 .. 607 698 .. 576 715 .. 0.87 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00019 Kinase-like 151 TlqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvv..sevekgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysi 244 q++r +L k +h ++ ++n+l e+ +++ +f+ L r+ ++v +++ g P ++ ++ + r t + d+W+ G+ ++ i FUN_002080-T2 607 GYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFG-LARDIHQVDyyRKTTDGRLPVKWMALEAL-FDR----VYTTQSDVWAFGILLWEI 696 569************************************7.8999988887789999999*999999777.877....788889*******99888 PP Kinase-like 245 wc 246 FUN_002080-T2 697 VT 698 65 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 2 2.9e+03 32 108 .. 96 115 .. 66 121 .. 0.71 2 ? 8.5 0.0 0.0018 2.6 18 34 .. 156 172 .. 150 185 .. 0.88 3 ? -1.5 0.0 2.2 3.2e+03 2 34 .. 236 269 .. 235 322 .. 0.70 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 2 Ig_PDGFR_d4 32 WfiCkdikkCsnktsatplennsseevsletnvtyeeeekesqvesqltfqkveetlavrCeaknelgadsrevkLv 108 ++ C a+n+ g+++ +Lv FUN_002080-T2 96 FY---------------------------------------------------------TCVAENSCGRKAITWRLV 115 34.........................................................455555555555555554 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0018 Ig_PDGFR_d4 18 vtCvaeGmPqPeveWfi 34 + C a+G+P+P+v W+ FUN_002080-T2 156 MDCSATGYPKPTVIWYK 172 67*************96 PP == domain 3 score: -1.5 bits; conditional E-value: 2.2 Ig_PDGFR_d4 2 kilelsd.shassgeqtvtCvaeGmPqPeveWfi 34 k+l++++ + + ++ t+ C a +P+ +W+ FUN_002080-T2 236 KVLKMENaTAVEGENATLLCKALSDSMPHFQWLR 269 6677777444556667888998888888888864 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (732 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 798 (0.031239); expected 510.9 (0.02) Passed bias filter: 742 (0.0290468); expected 510.9 (0.02) Passed Vit filter: 92 (0.00360149); expected 25.5 (0.001) Passed Fwd filter: 17 (0.000665492); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.38u 0.40s 00:00:00.78 Elapsed: 00:00:00.41 # Mc/sec: 7114.89 // Query: FUN_002080-T3 [L=675] Description: FUN_002080 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-52 177.5 0.1 6.3e-52 176.9 0.1 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.5e-40 138.1 0.5 3e-13 50.5 0.0 4.4 3 Ig_3 Immunoglobulin domain 2.9e-36 123.9 0.1 2e-12 47.4 0.0 4.4 4 I-set Immunoglobulin I-set domain 2.4e-29 103.0 0.1 3.9e-29 102.3 0.1 1.3 1 Pkinase Protein kinase domain 6.7e-29 100.5 0.1 5.8e-10 39.8 0.0 4.0 3 ig Immunoglobulin domain 8.3e-24 84.1 2.1 1.8e-08 35.0 0.0 4.2 3 Ig_2 Immunoglobulin domain 1.9e-17 63.9 0.8 5.4e-05 23.8 0.0 5.5 4 V-set Immunoglobulin V-set domain 0.0022 18.4 0.0 0.18 12.3 0.0 3.2 3 C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C 0.003 18.1 2.1 0.4 11.2 0.0 3.9 4 C2-set_2 CD80-like C2-set immunoglobulin domain ------ inclusion threshold ------ 0.018 15.3 0.3 5.4 7.4 0.1 3.7 4 Adeno_E3_CR1 Adenovirus E3 region protein CR1 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 ABC1 ABC1 atypical kinase-like domain 0.028 14.7 0.2 0.06 13.7 0.2 1.5 1 DUF5337 Family of unknown function (DUF5337) 0.099 13.7 0.6 8.3 7.5 0.1 3.5 3 Ig_4 T-cell surface glycoprotein CD3 delta chain 0.13 12.7 1.1 24 5.5 0.4 2.6 2 Syndecan Syndecan domain 0.14 12.7 0.0 0.92 10.1 0.0 2.4 2 Ig_C17orf99 C17orf99 Ig domain 0.16 12.4 0.1 2.4 8.6 0.0 2.8 3 Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-li Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.9 0.1 3.9e-55 6.3e-52 2 163 .. 493 662 .. 492 667 .. 0.96 Alignments for each domain: == domain 1 score: 176.9 bits; conditional E-value: 3.9e-55 PK_Tyr_Ser-Thr 2 elkeklGeGafGeVykgtlke.ekekkkikVavKtlkeeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrk 94 ++ lGeGafG+V+k+++ + + k +VavK+lke+a+++e +++++e+++mk++ +h+ni++l+g+ct+++pl++v+ey+++G+L++fLr+ FUN_002080-T3 493 NFVGVLGEGAFGRVMKAEIIGlPSMPFKFNVAVKMLKEDATDHELADLVSEMEVMKTIgKHKNIINLIGACTQGGPLYVVVEYASNGNLRQFLRE 587 56778***************97778889******************************************************************* PP PK_Tyr_Ser-Thr 95 k......keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkek 163 + +++l+l +l+++ +q+ +GmeyL+ kk++HrdlaarN+Lv e+++ ki+DfGLard+++ dyy+k+++ FUN_002080-T3 588 RrptkeySTTLTLVDLVSFGYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQVDYYRKTTD 662 *****9999*************************************************************99876 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.5 0.0 1.9e-16 3e-13 2 78 .] 24 103 .. 23 103 .. 0.93 2 ! 44.8 0.0 1.2e-14 1.8e-11 13 78 .] 148 214 .. 132 214 .. 0.83 3 ! 36.1 0.1 5.8e-12 9.3e-09 1 78 [] 234 339 .. 234 339 .. 0.83 Alignments for each domain: == domain 1 score: 50.5 bits; conditional E-value: 1.9e-16 Ig_3 2 PvitvspsstvveegesvtLtCea....egnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P+i+++ + t v ege+++L C++ +++++p + W kn+++l++ s+ + ++ + ++ L+i++v++ed+G YtCvA+N FUN_002080-T3 24 PKIRTKGNITLVPEGEEARLICSVndkgTSGNKPIVFWEKNNETLQPASHNR-MRIKPYRYLKIKRVSKEDAGFYTCVAEN 103 99**9999999***************999999***********977766654.99*************************9 PP == domain 2 score: 44.8 bits; conditional E-value: 1.2e-14 Ig_3 13 veegesvtLtCeaegnppptitWykngkelssgstskr..sssssnstLtisnvtredsGtYtCvAsN 78 + +g+s+++ C+a+g+p+pt+ Wyk+ ++ + + + + ++ ++i+++ + dsG YtC +sN FUN_002080-T3 148 IPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGG-SklHIGMFQTLVIIRDAVPADSGIYTCNVSN 214 789*************************84443333.2478999999999*****************9 PP == domain 3 score: 36.1 bits; conditional E-value: 5.8e-12 Ig_3 1 kPvitvspsstvveegesvtLtCeaegnppptitWykngke..lssgstskr...............................sssssnstLtisn 63 kP++ + t ++ege++tL C+a +++ p+++W++ ++s + + + ++ +L++ n FUN_002080-T3 234 KPKVLKMENAT-AVEGENATLLCKALSDSMPHFQWLRWLASpsNTS--N--QsseienpvyevikqneqngnkqlllpnghtsKLDFHGVKLILVN 324 67777555555.7************************999753222..2..2235799********999999999999999988888888999999 PP Ig_3 64 vtredsGtYtCvAsN 78 vt++d+G+Y+C++ N FUN_002080-T3 325 VTKKDEGKYSCIVGN 339 ************987 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.4 0.0 1.3e-15 2e-12 1 88 [. 24 114 .. 24 116 .. 0.87 2 ! 46.5 0.0 2.6e-15 4.1e-12 10 87 .. 146 224 .. 140 227 .. 0.84 3 ! 8.8 0.0 0.0014 2.3 6 37 .. 239 270 .. 236 289 .. 0.85 4 ! 15.7 0.0 1e-05 0.017 49 85 .. 313 347 .. 297 352 .. 0.78 Alignments for each domain: == domain 1 score: 47.4 bits; conditional E-value: 1.3e-15 I-set 1 pkftqklkdvevkeGesaeleckvsGe....pepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeL 88 pk+ +k + + v eGe+a+l c+v + +p v W k+++ l++ ++ +++ + L+I++v+keD+G Ytc+a+ns g++ + +L FUN_002080-T3 24 PKIRTKGNITLVPEGEEARLICSVNDKgtsgNKPIVFWEKNNETLQPASHNRMRIKP-YRYLKIKRVSKEDAGFYTCVAENSCGRKAITWRL 114 5666777777899***********755335569**********************99.778***********************99888776 PP == domain 2 score: 46.5 bits; conditional E-value: 2.6e-15 I-set 10 vevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaee.gtatLtIsnvkkeDeGkYtckatnsageaeasae 87 +++ +G+s +++c+++G p+p+v W+kd+ ++e k + + + ++ +I+++ ++D+G+Ytc+++n +g + s + FUN_002080-T3 146 IAIPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGGSKLHIGmFQTLVIIRDAVPADSGIYTCNVSNAYGWINNSYK 224 57889****************************9666665555535577789******************997666655 PP == domain 3 score: 8.8 bits; conditional E-value: 0.0014 I-set 6 klkdvevkeGesaeleckvsGepepevsWlkd 37 k++++++ eGe+a+l ck+ + p+++Wl+ FUN_002080-T3 239 KMENATAVEGENATLLCKALSDSMPHFQWLRW 270 678999***********************975 PP == domain 4 score: 15.7 bits; conditional E-value: 1e-05 I-set 49 vkaeegtatLtIsnvkkeDeGkYtckatnsageaeas 85 +++ + +L++ nv+k+DeGkY+c + n +g a ++ FUN_002080-T3 313 LDFHG--VKLILVNVTKKDEGKYSCIVGNAIGYAVQQ 347 44444..8999*******************9987665 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.3 0.1 2.5e-32 3.9e-29 4 152 .. 495 655 .. 492 665 .. 0.86 Alignments for each domain: == domain 1 score: 102.3 bits; conditional E-value: 2.5e-32 Pkinase 4 leklGeGsfgkVykav.....eketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdllsrkg 93 + lGeG+fg+V+ka + + vA+K++k++ ++++ ++++E++++k++ h+ni++li+++++ ly+v+Ey+++g+l ++l++++ FUN_002080-T3 495 VGVLGEGAFGRVMKAEiiglpSMPFKFNVAVKMLKEDATDHEL-ADLVSEMEVMKTIGkHKNIINLIGACTQGGPLYVVVEYASNGNLRQFLRERR 589 5689********9986222223345668*******99888866.69***********99**********************************666 PP Pkinase 94 alsee.......eakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesss 152 +e ++ ++ +q+++g+eyl ++++HrDl NiL+ e+++lKi+DFGla+ +++ FUN_002080-T3 590 PTKEYsttltlvDLVSFGYQVVRGMEYLSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQVD 655 666666666666999*********************************************999855 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.8 0.0 3.6e-13 5.8e-10 4 74 .. 34 105 .. 33 111 .. 0.93 2 ! 31.6 0.0 1.4e-10 2.2e-07 4 73 .. 147 215 .. 145 220 .. 0.91 3 ! 23.9 0.1 3.4e-08 5.4e-05 4 75 .. 244 342 .. 241 345 .. 0.77 Alignments for each domain: == domain 1 score: 39.8 bits; conditional E-value: 3.6e-13 ig 4 tvleGesatLtCsas...egspgpdvtWskegktkieslkvkedngrttqs...sllisnvteedaGtYtCvvnnpg 74 +v+eGe a+L Cs++ ++ p+v+W+k+++t++ ++ +r+++ l i +v++edaG+YtCv++n+ FUN_002080-T3 34 LVPEGEEARLICSVNdkgTSGNKPIVFWEKNNETLQPASH-----NRMRIKpyrYLKIKRVSKEDAGFYTCVAENSC 105 799*************9999999*****************.....99999988889******************985 PP == domain 2 score: 31.6 bits; conditional E-value: 1.4e-10 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnp 73 +++G+s+++ Csa+ g p p+v+W k++ +e + +++q+ + i+++ + d+G YtC v+n+ FUN_002080-T3 147 AIPVGNSFRMDCSAT-GYPKPTVIWYKDKALFQERKGGSKLHIGMFQTLVIIRDAVPADSGIYTCNVSNA 215 5789***********.*************99999988666667889**********************97 PP == domain 3 score: 23.9 bits; conditional E-value: 3.4e-08 ig 4 tvleGesatLtCsasegspgpdvtWskegktkieslk............vkedngrttqs..................sllisnvteedaGtYtCv 69 t+ eGe+atL C+a +++ p+++W + ++ +++ + +++ + ++ l ++nvt++d+G Y+C FUN_002080-T3 244 TAVEGENATLLCKAL-SDSMPHFQWLRWLASPSNTSNqsseienpvyevI--KQNEQNGNkqlllpnghtskldfhgvKLILVNVTKKDEGKYSCI 336 6679***********.*********8754444333333466988888531..333333335789******************************** PP ig 70 vnnpgg 75 v n+ g FUN_002080-T3 337 VGNAIG 342 988765 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.0 0.0 4.7e-11 7.5e-08 3 66 .. 25 104 .. 23 111 .. 0.78 2 ! 35.0 0.0 1.1e-11 1.8e-08 10 72 .. 147 220 .. 135 227 .. 0.81 3 ! 11.8 0.2 0.00019 0.31 3 65 .. 237 339 .. 234 351 .. 0.74 Alignments for each domain: == domain 1 score: 33.0 bits; conditional E-value: 4.7e-11 Ig_2 3 vltasp..tvvtegesvtLtCsas.....gnppakytwykdgkvls.ssqn........fft.snvsaedsGtYtCtarnt 66 +++ t v+ege+ +L Cs+ gn ++ + w k+++ l+ s+n ++ ++vs ed+G YtC+a+n+ FUN_002080-T3 25 KIRTKGniTLVPEGEEARLICSVNdkgtsGN-KPIVFWEKNNETLQpASHNrmrikpyrYLKiKRVSKEDAGFYTCVAENS 104 55543344779*************8887444.67799*****99996466678899887443599*************996 PP == domain 2 score: 35.0 bits; conditional E-value: 1.1e-11 Ig_2 10 vvtegesvtLtCsasgnppakytwykdgkvlsssqn............fftsnvsaedsGtYtCtarntkggkvs 72 ++ g s+++ Csa g p++++ wykd +++++ ++++ + + dsG+YtC ++n g + FUN_002080-T3 147 AIPVGNSFRMDCSATGYPKPTVIWYKDKALFQERKGgsklhigmfqtlVIIRDAVPADSGIYTCNVSNAY-GWIN 220 5789************************9999666666888898777666799***************54.4444 PP == domain 3 score: 11.8 bits; conditional E-value: 0.00019 Ig_2 3 vltasptvvtegesvtLtCsasgnppakytwykdg..................kvls.ssqn.....................fftsnvsaedsGt 58 vl ++ + ege+ tL C+a ++ + ++w + +v++ + qn +++ nv+ d G FUN_002080-T3 237 VLKMENATAVEGENATLLCKALSDSMPHFQWLRWLaspsntsnqsseienpvyEVIKqNEQNgnkqlllpnghtskldfhgvkLILVNVTKKDEGK 332 5677778899**********99887788888876666778888998888888856654223344775655555566666666444466******** PP Ig_2 59 YtCtarn 65 Y+C ++n FUN_002080-T3 333 YSCIVGN 339 *****99 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.021 33 7 39 .. 34 67 .. 29 73 .. 0.89 2 ! 11.3 0.0 0.00026 0.41 74 98 .. 83 106 .. 71 116 .. 0.83 3 ! 13.7 0.0 4.8e-05 0.077 72 96 .. 192 216 .. 144 228 .. 0.63 4 ! 23.8 0.0 3.4e-08 5.4e-05 7 95 .. 244 341 .. 240 352 .. 0.74 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.021 V-set 7 tvaeGesvtLtCslsss.eseasqsvyWyrqppg 39 v+eGe ++L Cs++++ +s + v W + ++ FUN_002080-T3 34 LVPEGEEARLICSVNDKgTSGNKPIVFWEKNNET 67 699************9999999999***998865 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00026 V-set 74 sltiqnltlsDsGtYtCavipkgev 98 l+i+ ++ +D+G+YtC+ +++++ FUN_002080-T3 83 YLKIKRVSKEDAGFYTCV-AENSCG 106 599**************9.566555 PP == domain 3 score: 13.7 bits; conditional E-value: 4.8e-05 V-set 72 dfsltiqnltlsDsGtYtCavipkg 96 + i+++ ++DsG+YtC+v + + FUN_002080-T3 192 QTLVIIRDAVPADSGIYTCNVSNAY 216 45679***************84443 PP == domain 4 score: 23.8 bits; conditional E-value: 3.4e-08 V-set 7 tvaeGesvtLtCslssseseasqsvyWyrqppgk.....epteliayysnkseeekkkgrfslrkdpsrsdfs...ltiqnltlsDsGtYtCav.i 93 t++eGe++tL C+ s + + q+++W p+++ e + ++ +++e++ +k+ ++++s+ df+ l + n+t +D+G Y C v + FUN_002080-T3 244 TAVEGENATLLCKALSDSMPHFQWLRWLASPSNTsnqssEIENPVYEVIKQNEQNGNKQLLLPNGHTSKLDFHgvkLILVNVTKKDEGKYSCIVgN 339 899*********88888778***********998654443333444444466666667777777777777764444****************9754 PP V-set 94 pk 95 + FUN_002080-T3 340 AI 341 44 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.49 7.9e+02 29 80 .. 56 104 .. 23 108 .. 0.65 2 ! 12.3 0.0 0.00011 0.18 16 79 .. 153 214 .. 146 217 .. 0.77 3 ? 0.3 0.0 0.64 1e+03 62 80 .. 322 340 .. 295 343 .. 0.76 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.49 C2-set_3 29 ePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnp 80 +P v W++++ +l+++s++ + ++ ++ v+++ + ++C+ +n+ FUN_002080-T3 56 KPIVFWEKNNE-TLQPASHNRMRI--KPYRYLKIKRVSKEDAGFYTCVAENS 104 78889987766.666666644433..34555555566666667777777775 PP == domain 2 score: 12.3 bits; conditional E-value: 0.00011 C2-set_3 16 girlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvre...ssnknvsCsirn 79 r+ C+++G yP+P+v W++ k l ++ + s+ + g+f++ +++r+ + ++ ++C ++n FUN_002080-T3 153 SFRMDCSATG-YPKPTVIWYKDKA--LFQERKGGSKLHIGMFQT--LVIIRDavpADSGIYTCNVSN 214 5689998887.********98876..888888889999999976..566666444556778888888 PP == domain 3 score: 0.3 bits; conditional E-value: 0.64 C2-set_3 62 slvvressnknvsCsirnp 80 + v+++ ++++sC++ n FUN_002080-T3 322 LVNVTKKDEGKYSCIVGNA 340 456889999*******996 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.16 2.6e+02 12 45 .. 37 72 .. 25 86 .. 0.68 2 ? 1.0 0.1 0.39 6.2e+02 20 36 .. 98 114 .. 84 139 .. 0.84 3 ! 11.2 0.0 0.00025 0.4 15 39 .. 152 175 .. 132 190 .. 0.81 4 ? -1.8 0.0 3.1 4.9e+03 10 48 .. 246 282 .. 238 292 .. 0.55 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.16 C2-set_2 12 aeekevvatCv....saggkPapritWlldgkeleaae 45 ++e + C+ ++g+ +p + W++++++l+ a+ FUN_002080-T3 37 E-GEEARLICSvndkGTSGN-KPIVFWEKNNETLQPAS 72 2.468888899777645555.47888999998884443 PP == domain 2 score: 1.0 bits; conditional E-value: 0.39 C2-set_2 20 tCvsaggkPapritWll 36 tCv++++ + itW l FUN_002080-T3 98 TCVAENSCGRKAITWRL 114 9**************86 PP == domain 3 score: 11.2 bits; conditional E-value: 0.00025 C2-set_2 15 kevvatCvsaggkPapritWlldgk 39 + ++C sa g+P+p++ W++d FUN_002080-T3 152 NSFRMDC-SATGYPKPTVIWYKDKA 175 5677899.99***********9965 PP == domain 4 score: -1.8 bits; conditional E-value: 3.1 C2-set_2 10 leaeekevvatCvsaggkPapritWlldgkel.eaaetss 48 +e+e + ++ C a + p+ +Wl+ + +++++ss FUN_002080-T3 246 VEGE--NATLLC-KALSDSMPHFQWLRWLASPsNTSNQSS 282 4444..666667.444444557777766655422333333 PP >> Adeno_E3_CR1 Adenovirus E3 region protein CR1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.74 1.2e+03 62 83 .. 84 105 .. 51 117 .. 0.81 2 ? 2.5 0.0 0.11 1.8e+02 17 37 .. 157 174 .. 142 229 .. 0.72 3 ? -3.4 0.0 7.8 1.2e+04 8 21 .. 241 254 .. 238 268 .. 0.81 4 ? 7.4 0.1 0.0034 5.4 59 78 .. 317 336 .. 292 348 .. 0.84 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.74 Adeno_E3_CR1 62 LtLlnvtktyeGtYygtnkkss 83 L + v+k++ G+Y + ++s FUN_002080-T3 84 LKIKRVSKEDAGFYTCVAENSC 105 567789999*****99988874 PP == domain 2 score: 2.5 bits; conditional E-value: 0.11 Adeno_E3_CR1 17 nltLvGpsegkVtWykleedg 37 +++ +G+++ V+Wy +d+ FUN_002080-T3 157 DCSATGYPKPTVIWY---KDK 174 78889**********...333 PP == domain 3 score: -3.4 bits; conditional E-value: 7.8 Adeno_E3_CR1 8 knvtvtvgsnltLv 21 +n t+ g+n+tL FUN_002080-T3 241 ENATAVEGENATLL 254 67788899999985 PP == domain 4 score: 7.4 bits; conditional E-value: 0.0034 Adeno_E3_CR1 59 kqnLtLlnvtktyeGtYygt 78 + L+L+nvtk++eG Y + FUN_002080-T3 317 GVKLILVNVTKKDEGKYSCI 336 678**************986 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 3.2e-05 0.051 184 220 .. 617 653 .. 595 670 .. 0.86 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 3.2e-05 ABC1 184 ifedgffhaDphpGNllvrkdgelvllDfGlmgelde 220 + ++++h D+ + N+lv ++++l + DfGl +++++ FUN_002080-T3 617 LSLKKCIHRDLAARNILVGEENTLKIADFGLARDIHQ 653 667899***************************9964 PP >> DUF5337 Family of unknown function (DUF5337) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.2 3.8e-05 0.06 36 71 .. 379 414 .. 374 416 .. 0.93 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 3.8e-05 DUF5337 36 qlGlpaRfalLfdLaAlAaliwalvvtyqiwraRqn 71 + G + + ++++ +a++ ++++a +v + ++r+R++ FUN_002080-T3 379 ATGTSSKAKVFISFAVVLGFVFAAIVGLLVYRHRRR 414 7899******************************97 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 0.1 0.0052 8.3 15 50 .. 59 102 .. 39 111 .. 0.73 2 ? 1.5 0.0 0.4 6.4e+02 40 49 .. 203 214 .. 157 231 .. 0.72 3 ? -0.2 0.0 1.4 2.2e+03 31 48 .. 319 336 .. 295 349 .. 0.76 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0052 Ig_4 15 itwlkdgkeikeskek........tldlgksiedprglYqCkee 50 + w k++++ + ++++ l+++++++++ g Y+C e FUN_002080-T3 59 VFWEKNNETLQPASHNrmrikpyrYLKIKRVSKEDAGFYTCVAE 102 567777777666665555666666899**************853 PP == domain 2 score: 1.5 bits; conditional E-value: 0.4 Ig_4 40 dprglYqCk..e 49 ++g+Y+C+ + FUN_002080-T3 203 ADSGIYTCNvsN 214 578999998431 PP == domain 3 score: -0.2 bits; conditional E-value: 1.4 Ig_4 31 tldlgksiedprglYqCk 48 +l l ++++ ++g Y+C FUN_002080-T3 319 KLILVNVTKKDEGKYSCI 336 78889999999******6 PP >> Syndecan Syndecan domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.024 38 28 43 .. 319 334 .. 317 340 .. 0.85 2 ? 5.5 0.4 0.015 24 15 36 .. 393 413 .. 384 415 .. 0.80 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.024 Syndecan 28 lllvYrmrKKDEGsYa 43 l++ + KKDEG Y+ FUN_002080-T3 319 KLILVNVTKKDEGKYS 334 57777899*******6 PP == domain 2 score: 5.5 bits; conditional E-value: 0.015 Syndecan 15 GvvvgllfavllvlllvYrmrK 36 vv+g++fa +v llvYr r+ FUN_002080-T3 393 AVVLGFVFAA-IVGLLVYRHRR 413 6788999986.789*****886 PP >> Ig_C17orf99 C17orf99 Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.00058 0.92 13 90 .. 35 115 .. 23 119 .. 0.74 2 ? -3.1 0.0 7.6 1.2e+04 16 31 .. 248 263 .. 240 265 .. 0.83 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00058 Ig_C17orf99 13 fpksrrvlisCha....segspPItYsLvgkkgivvakkivkegkPAnFsllitlkssPdlltyaCqAantsgvqasslvLq 90 +p+++ + + C ++g +PI++ +++ a + kP ++ l+i s+ d y+C+A+n+ g +a + +L+ FUN_002080-T3 35 VPEGEEARLICSVndkgTSGNKPIVFWEKNNETLQPASHNRMRIKPYRY-LKIKRVSKEDAGFYTCVAENSCGRKAITWRLV 115 6777777777765222257899999875555555555555556668876.99*********************999888886 PP == domain 2 score: -3.1 bits; conditional E-value: 7.6 Ig_C17orf99 16 srrvlisChasegspP 31 ++ ++++C+a + s P FUN_002080-T3 248 GENATLLCKALSDSMP 263 6778899999999988 PP >> Ig_PDGFR_d4 Platelet-derived growth factor receptor Ig-like domain 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 1.5 2.5e+03 32 108 .. 96 115 .. 64 122 .. 0.71 2 ? 8.6 0.0 0.0015 2.4 18 34 .. 156 172 .. 150 185 .. 0.88 3 ? -1.4 0.0 1.8 2.9e+03 2 34 .. 236 269 .. 235 323 .. 0.70 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1.5 Ig_PDGFR_d4 32 WfiCkdikkCsnktsatplennsseevsletnvtyeeeekesqvesqltfqkveetlavrCeaknelgadsrevkLv 108 ++ C a+n+ g+++ +Lv FUN_002080-T3 96 FY---------------------------------------------------------TCVAENSCGRKAITWRLV 115 34.........................................................456666665555555555 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0015 Ig_PDGFR_d4 18 vtCvaeGmPqPeveWfi 34 + C a+G+P+P+v W+ FUN_002080-T3 156 MDCSATGYPKPTVIWYK 172 67*************96 PP == domain 3 score: -1.4 bits; conditional E-value: 1.8 Ig_PDGFR_d4 2 kilelsd.shassgeqtvtCvaeGmPqPeveWfi 34 k+l++++ + + ++ t+ C a +P+ +W+ FUN_002080-T3 236 KVLKMENaTAVEGENATLLCKALSDSMPHFQWLR 269 6677777444556667888998888888888864 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (675 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1083 (0.0423958); expected 510.9 (0.02) Passed bias filter: 984 (0.0385203); expected 510.9 (0.02) Passed Vit filter: 104 (0.00407125); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.40u 0.41s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 6448.87 // Query: FUN_002081-T1 [L=105] Description: FUN_002081 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (105 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 336 (0.0131533); expected 510.9 (0.02) Passed bias filter: 271 (0.0106087); expected 510.9 (0.02) Passed Vit filter: 12 (0.000469759); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1079.81 // Query: FUN_002082-T1 [L=247] Description: FUN_002082 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-23 82.2 16.6 7.7e-23 81.5 16.6 1.3 1 Sprouty Sprouty protein (Spry) Domain annotation for each model (and alignments): >> Sprouty Sprouty protein (Spry) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 81.5 16.6 3e-27 7.7e-23 16 109 .. 138 231 .. 125 239 .. 0.81 Alignments for each domain: == domain 1 score: 81.5 bits; conditional E-value: 3e-27 Sprouty 16 nlpskwlckkclcsaesvidavsclccvkallYHcasdkegddsladepCsacse..erlvkrwlllallslllPCLlcYlplraclkvcekcyak 109 + + c+ s++ +id++sc+c vka+lYHc++d+ ++ s++++pCs c + ++++ rw +l++ s+llPCLlcYlpl++c +vc+ cy+k FUN_002082-T1 138 HEDDDIKLFCCKRSVDMLIDYASCMCGVKAVLYHCSKDSFDEGSVSEHPCS-CGPpeKSCMGRWGCLVACSVLLPCLLCYLPLKGCSEVCV-CYKK 231 444443334577789************************************.655458899*****************************7.6664 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (247 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 845 (0.0330789); expected 510.9 (0.02) Passed bias filter: 449 (0.0175768); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2459.49 // Query: FUN_002083-T1 [L=99] Description: FUN_002083 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 444 (0.0173811); expected 510.9 (0.02) Passed bias filter: 378 (0.0147974); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 977.08 // Query: FUN_002084-T1 [L=229] Description: FUN_002084 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-29 102.5 1.1 2.1e-29 102.5 1.1 1.4 2 FGF Fibroblast growth factor ------ inclusion threshold ------ 0.082 13.4 0.3 0.19 12.3 0.3 1.7 1 Plk4_PB1 Polo-like Kinase 4 Polo Box 1 0.13 12.9 0.0 0.25 12.0 0.0 1.4 1 Fascin Fascin domain Domain annotation for each model (and alignments): >> FGF Fibroblast growth factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 1.6 1.4e+04 47 62 .. 28 43 .. 14 49 .. 0.52 2 ! 102.5 1.1 2.5e-33 2.1e-29 1 123 [. 70 194 .. 70 196 .. 0.94 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 1.6 FGF 47 ikgvesglYlamnkkG 62 + + +s + l +nk+ FUN_002084-T1 28 VYSGKSSRCLQLNKSV 43 4444444444444444 PP == domain 2 score: 102.5 bits; conditional E-value: 2.5e-33 FGF 1 rvrrLYsrtsgfhlqilpdgkvsgtkeesskysileiesvsvgvvrikgvesglYlamnkkGklyg...sknfte..eckfkekleennYntyaSa 91 r+++LYsr s+ h+qi++ +v+++++++s+y+ l +es++++++ri+g + ++Yl++nkkG+l++ +++ft +c f+e+++ +++ +y+S+ FUN_002084-T1 70 RKVQLYSRASQLHIQIRK-SEVDARGQDGSEYARLVLESDNFRRIRIRGEKANRYLCVNKKGELVArikKQRFTVmkRCIFNEEITGEGWFQYRST 164 689**************9.9*********************************************9665577774459****************** PP FGF 92 kykerewyvalkkkGrpkkgkktkkeqkaahF 123 ky + ++++k Grp++g+k+ k++k +F FUN_002084-T1 165 KY--PSFVIGFSKAGRPMNGRKSAKRSKYRQF 194 **..**********************999988 PP >> Plk4_PB1 Polo-like Kinase 4 Polo Box 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.3 2.3e-05 0.19 64 105 .. 175 216 .. 106 218 .. 0.82 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 2.3e-05 Plk4_PB1 64 grgvplndreseeedsrkvYsldnLPekywkkYqyaakFvel 105 + g p+n r+s+++ ++++++l +LPe+ ++k + a+ ++l FUN_002084-T1 175 KAGRPMNGRKSAKRSKYRQFTLRELPERKHRKHRRNARLLRL 216 567889999*9*********************9988887765 PP >> Fascin Fascin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 3e-05 0.25 9 67 .. 85 142 .. 79 163 .. 0.80 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 3e-05 Fascin 9 krgaklsanredekavqvftLefdeesya.lr.ssngkYlsadsdgrvvaeaeeaedtfFe 67 r+ +++a+++d +++ ++Le d+ + + +r ++Yl ++++g++va+ + + +F+ FUN_002084-T1 85 IRKSEVDARGQDGSEYARLVLESDNFRRIrIRgEKANRYLCVNKKGELVARIK---KQRFT 142 67899*****************877766669977899************9988...33333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (229 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 676 (0.0264631); expected 510.9 (0.02) Passed bias filter: 439 (0.0171854); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.35s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 2252.46 // Query: FUN_002085-T1 [L=268] Description: FUN_002085 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-31 108.6 3.0 6.5e-31 107.4 3.0 1.6 1 FGF Fibroblast growth factor ------ inclusion threshold ------ 0.7 10.1 2.4 19 5.5 0.1 2.5 2 TFA2_Winged_2 TFA2 Winged helix domain 2 Domain annotation for each model (and alignments): >> FGF Fibroblast growth factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.4 3.0 5.1e-35 6.5e-31 1 124 [] 56 177 .. 56 177 .. 0.98 Alignments for each domain: == domain 1 score: 107.4 bits; conditional E-value: 5.1e-35 FGF 1 rvrrLYsrtsgfhlqilpdgkvsgtkeesskysileiesvsvgvvrikgvesglYlamnkkGklygsknfte.eckfkekleennYntyaSakyke 95 r ++LYsr+s+ hl+i++ +k+++ +++++ky++l ies+++g+vri+g +++Yl++++++ +g+k++++ +c+f+ek+ n+Y+ + Sa+ FUN_002085-T1 56 RETQLYSRSSRSHLRIHG-KKIDALGRDGDKYAKLVIESDNFGRVRIRGSLTNYYLCIKRNSTFIGRKATKSrRCVFYEKYAVNHYTEFLSAYN-- 148 679**************9.*************************************************99999*********************.. PP FGF 96 rewyvalkkkGrpkkgkktkkeqkaahFl 124 + w ++++k+G+++ g k +++qk+++F+ FUN_002085-T1 149 ESWTISVSKRGKMRTGYKGRRGQKTVQFI 177 ***************************96 PP >> TFA2_Winged_2 TFA2 Winged helix domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.0014 19 15 48 .. 182 211 .. 172 220 .. 0.76 2 ? 3.8 0.5 0.0049 63 1 15 [. 250 265 .. 250 268 .] 0.83 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.0014 TFA2_Winged_2 15 agGisvkdLkds.wpdveeaieeLekegkilvlrt 48 + i+ k++k+s +p+ ++ie+L + + rt FUN_002085-T1 182 KIIIKTKNVKESlYPGLRDHIEKLLR-----AYRT 211 56789999****99**********87.....4445 PP == domain 2 score: 3.8 bits; conditional E-value: 0.0049 TFA2_Winged_2 1 knkeeLlalLkkqs.a 15 ++k++Ll+lL++++ + FUN_002085-T1 250 RSKKALLKLLRREQrK 265 79*********99765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (268 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1480 (0.057937); expected 510.9 (0.02) Passed bias filter: 714 (0.0279507); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2639.91 // Query: FUN_002087-T1 [L=274] Description: FUN_002087 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.1e-33 113.5 0.1 1.3e-32 112.9 0.1 1.3 1 FGF Fibroblast growth factor Domain annotation for each model (and alignments): >> FGF Fibroblast growth factor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 112.9 0.1 5.2e-37 1.3e-32 1 123 [. 59 182 .. 59 183 .. 0.91 Alignments for each domain: == domain 1 score: 112.9 bits; conditional E-value: 5.2e-37 FGF 1 rvrrLYsrtsgfhlqilpdgkvsgtkeesskysileiesvsvgvvrikgvesglYlamnkkGklygsknfte..eckfkekleennYntyaSakyk 94 r +LYsr+sg+h++i++d++v++++e+++ky++l iesvs+g+v+i+g +++Yl+++k+G+l ++++ ++ +c+f+++l +n ++ ++S+ky FUN_002087-T1 59 RFIQLYSRNSGRHVRIKEDRSVDASGEDGDKYAKLIIESVSFGRVHIRGSVTNFYLCVDKRGRLKARARGKWkdNCVFTDHLADNAFTEFRSVKY- 153 5679**************************************************************87666334*********************. PP FGF 95 erewyvalkkkGrpkkgkk.tkkeqkaahF 123 ++ +a++++Grp++ ++ + ++ka +F FUN_002087-T1 154 -NKTLIAFNRSGRPRQVNRpFRAGMKAFQF 182 .***************98625667777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (274 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 665 (0.0260325); expected 510.9 (0.02) Passed bias filter: 441 (0.0172637); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.43s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2762.93 // Query: FUN_002088-T1 [L=528] Description: FUN_002088 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00034 20.8 0.0 0.012 15.8 0.0 2.2 2 HECT HECT-domain (ubiquitin-transferase) ------ inclusion threshold ------ 0.88 10.6 4.8 2.4 9.2 4.8 1.7 1 DUF7287 Family of unknown function (DUF7287) Domain annotation for each model (and alignments): >> HECT HECT-domain (ubiquitin-transferase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 0.011 1.4e+02 41 85 .. 353 403 .. 316 432 .. 0.63 2 ! 15.8 0.0 9.3e-07 0.012 214 283 .. 461 524 .. 443 528 .] 0.86 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.011 xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxx RF HECT 41 kllGkllGkaiye.gllldlpfpraflkkllg.....kekltledleeidp 85 +l G+++G +++e +++ d + +afl ++ + +k+t +l d FUN_002088-T1 353 TLSGVFMGSCLFEeSTISDSFLLEAFLSYIGKdeaetLRKCTEGELDVNDD 403 466888888888734455566667777777665555522444444444444 PP == domain 2 score: 15.8 bits; conditional E-value: 9.3e-07 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 214 skvikwfweileefseeerrklLkFvTgssrlPlgGfkslpkltIqkksgkdddrLPtahTCfnlLklpe 283 + + + ++++++ e +++L+F Tgs+ + ++ ++t++++s + r P a+TC L++p FUN_002088-T1 461 RASFDHLKHYMKSLGEVALKAFLQFTTGSDVIAVT------EITVAFNSLDGAHRSPIARTCGPVLEVPT 524 5566778899999*******************999......89****9999*************999994 PP >> DUF7287 Family of unknown function (DUF7287) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 4.8 0.00019 2.4 42 133 .. 131 216 .. 122 234 .. 0.68 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00019 DUF7287 42 etv.qadRvAdelvedllspgepnvLdaectaaffeesesdeeelglraddsadteeealetdsvnVtienldgsvatlddvelaaGdevpdq 133 + v +adR A e++e+ + +++++++ a+ ++++++++++ + ++r++ s+ ++ +++++ +t ++ +v+ ++ aG++++++ FUN_002088-T1 131 DDVdIADRFAVEISEHSSATTSSTTVCAAASRSLTSTNSNA--AVACRFSGSTPVNA---SQSTAAITTAASTPDVTLN--ANQDAGQAATSD 216 55558*************99999999999999999999988..99***999987644...4555555555522222222..333344433333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (528 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1176 (0.0460364); expected 510.9 (0.02) Passed bias filter: 788 (0.0308475); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 4978.45 // Query: FUN_002089-T1 [L=221] Description: FUN_002089 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-17 64.9 0.0 1.8e-17 64.2 0.0 1.3 1 rva_4 Integrase core domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.2 0.0 7e-22 1.8e-17 40 172 .. 3 136 .. 1 154 [. 0.85 Alignments for each domain: == domain 1 score: 64.2 bits; conditional E-value: 7e-22 rva_4 40 leas.tnnrastvlkqflkavkky.glPsrvrsdkggenvkvallmnllrGlerssvitGrsvhnqrierlWrdvfkkvvsvfyslftaledseil 133 l+++ +nn+ + + flk+v++ g P ++r+d g+en +a + +++ ++ +++ +G s nqrie W+ k+ + + f++l ++ei+ FUN_002089-T1 3 LKVTkSNNHPDIIASFFLKCVEELgGCPVKLRTDCGTENGVMAAMQCTFQ-QSADAHKHGSSPANQRIESWWSFYRKNRCGWWMEFFKSLVEHEIF 97 555504566666667789999987369************98887655555.5669999************99999999999*************** PP rva_4 134 didndihllalhivylpriqkeleefknawnnhklrtek 172 ++ ++i++ +l + + +q +l++ k++wn+h +r + FUN_002089-T1 98 NPGDEIQMACLWFCFAHLLQDDLDKVKEHWNAHLIRGSR 136 ***********************************9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (221 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 695 (0.0272069); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2198.52 // Query: FUN_002090-T1 [L=187] Description: FUN_002090 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1230 (0.0481503); expected 510.9 (0.02) Passed bias filter: 680 (0.0266197); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1856.77 // Query: FUN_002091-T1 [L=300] Description: FUN_002091 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-27 96.9 10.5 2.8e-27 95.8 10.5 1.6 1 Sprouty Sprouty protein (Spry) ------ inclusion threshold ------ 0.012 14.9 4.7 0.02 14.2 4.7 1.4 1 Caldesmon Caldesmon Domain annotation for each model (and alignments): >> Sprouty Sprouty protein (Spry) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 95.8 10.5 2.2e-31 2.8e-27 25 109 .. 203 288 .. 182 294 .. 0.84 Alignments for each domain: == domain 1 score: 95.8 bits; conditional E-value: 2.2e-31 Sprouty 25 kclcsaesvidavsclccvkallYHcasdkegddsladepCsacse.erlvkrwlllallslllPCLlcYlplraclkvcekcyak 109 c ++a+++id+vsc+ccvk+++YHc++d+ ++ +l++epCs++ + ++++ rw +la+lsl+lPCL+cYlp+++c k+++++ +k FUN_002091-T1 203 LCGVEADELIDYVSCMCCVKGIFYHCTKDHYDEGQLVNEPCSCAGPlSSCAPRWGCLAFLSLFLPCLWCYLPAKGCKKAVSTTNSK 288 37788*************************************5555899*****************************99887764 PP >> Caldesmon Caldesmon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 4.7 1.6e-06 0.02 323 403 .. 76 153 .. 48 170 .. 0.79 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.6e-06 Caldesmon 323 kEeiErRRaEAAEkrqklpedslaeekkpFkclsP..kgsslKieE.RaefLNkSvkKsssvKsthppavvskIDdrLEqYtsA 403 k i R AA k +k +++ +a++++ + lsP k++s+K++ R++ Ks vKs h pa vs + rL Yt FUN_002091-T1 76 KPTISSHRSRAASKTKKTSSSDSADDGNEYCELSPtaKAPSIKLTSlRTQLST----KSVEVKSKHIPARVSSFERRL--YTDC 153 6678889************9999*******9999977899***9863665555....55568************9998..6655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (300 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1269 (0.049677); expected 510.9 (0.02) Passed bias filter: 470 (0.0183989); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.41s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 2988.04 // Query: FUN_002092-T1 [L=362] Description: FUN_002092 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-58 197.1 0.0 8.7e-58 196.7 0.0 1.1 1 ADP_ribosyl_GH ADP-ribosylglycohydrolase ------ inclusion threshold ------ 0.23 11.8 1.0 1.4 9.3 0.0 2.4 2 Gly-zipper_Omp Glycine zipper Domain annotation for each model (and alignments): >> ADP_ribosyl_GH ADP-ribosylglycohydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 196.7 0.0 6.8e-62 8.7e-58 1 286 [. 31 335 .. 31 336 .. 0.92 Alignments for each domain: == domain 1 score: 196.7 bits; conditional E-value: 6.8e-62 ADP_ribosyl_GH 1 gallGlavGDAlGapvefwsyeeirreygelgtdkrggghfglppgewtDDtqmalllaesLleaggfdpedlarrllkrWletpedgeprdigs 95 g+l+G++vGD+lGa +e+ s + i +ge+ + ++ + +++p ++tDD++m++++ +sLle++++d + +a +++k++++ ++ r++g+ FUN_002092-T1 31 GTLVGALVGDCLGANYEGVS-SVIP--FGEVTDYTMSRIKNKKDPIRYTDDSAMTRAICKSLLEQKRYDNRSMAVEFVKEFFK----DPTRGYGQ 118 79***************874.6777..888887778889999*****************************************....9******* PP ADP_ribosyl_GH 96 ttrealrnlkrgepppeagake.....ngsagnGalmRiaplgllyagdpeeaaelaresarlTHghpravagaaayaaavaaalrgesleeale 185 ++ +++++l++++p + + + + +gs gnGa+mRi pl+l+ + + +e+ e+a++ a +TH+h +v+ga+++a av +al+ e+++ FUN_002092-T1 119 AVGKVFERLRDDDPEDITFPARcqfdgQGSYGNGAAMRISPLALFSK-NSQELQEIACQNALITHAHICGVNGAIIQAIAVYKALHIEPPSLEPY 212 ***********9977777666677888*******************8.9***************************************9998888 PP ADP_ribosyl_GH 186 aa.....................leelalapadselaealdaaleladedeaeeaelavdelggggyvvealpaalyal.lragddfeeallrav 258 + +l + ++a ++++++el ++++a+e+e +v++lg+g+ ++ea+paa++++ l+++ +fe+++ +a+ FUN_002092-T1 213 NFiddlievaekieernvekrslSGSPSLPTRPFSYAGKMKEMKELFWQNDAQETETVVETLGNGIRAQEAVPAAIFSFvLKGKLSFEDSVNYAI 307 888999999999999999999887777888888899999999999999999*************************9983566889********* PP ADP_ribosyl_GH 259 nlGgDtDttaaiaGallGalyGleaiPe 286 +lGgDtDt+a+++Ga+ Ga++G+e++P+ FUN_002092-T1 308 SLGGDTDTIASMTGAISGAYWGVENVPA 335 **************************96 PP >> Gly-zipper_Omp Glycine zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.00011 1.4 16 36 .. 24 44 .. 23 46 .. 0.83 2 ? -0.1 0.2 0.1 1.3e+03 25 33 .. 319 327 .. 309 332 .. 0.55 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00011 Gly-zipper_Omp 16 avggagvGAaiGAavGalaGg 36 av++ ++G+++GA+vG +G+ FUN_002092-T1 24 AVLNKYRGTLVGALVGDCLGA 44 7888999999**999977776 PP == domain 2 score: -0.1 bits; conditional E-value: 0.1 Gly-zipper_Omp 25 aiGAavGal 33 + GA+ Ga+ FUN_002092-T1 319 MTGAISGAY 327 333333333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3489.83 // Query: FUN_002093-T1 [L=530] Description: FUN_002093 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-35 122.0 0.0 3.6e-12 46.7 0.0 4.2 3 I-set Immunoglobulin I-set domain 2e-34 118.4 0.1 3.8e-11 43.8 0.0 3.8 3 Ig_3 Immunoglobulin domain 3.6e-26 91.8 0.4 7e-08 33.2 0.0 4.6 3 ig Immunoglobulin domain 3.5e-24 85.3 0.0 1.3e-09 38.6 0.0 3.7 3 Ig_2 Immunoglobulin domain 3.6e-14 53.4 1.0 0.0065 17.1 0.0 5.5 4 V-set Immunoglobulin V-set domain 0.0011 19.2 0.0 0.36 11.1 0.0 2.9 3 Ig_6 Immunoglobulin domain 0.0053 17.3 0.0 12 6.4 0.0 3.2 3 DUF6584 Family of unknown function (DUF6584) ------ inclusion threshold ------ 0.018 16.1 0.0 3.6 8.7 0.0 3.0 2 Ig_4 T-cell surface glycoprotein CD3 delta chain 0.049 14.4 0.0 0.13 13.1 0.0 1.7 1 Orf78 Orf78 (ac78) 0.058 14.2 0.2 11 6.9 0.0 3.9 5 Zwei_Ig_N Zwei immunoglobulin domain protein, N-termina 0.095 11.7 0.3 0.13 11.3 0.3 1.1 1 SID-1_RNA_chan dsRNA-gated channel SID-1 0.16 12.3 0.2 0.47 10.8 0.0 1.9 2 TMEM154 TMEM154 protein family Domain annotation for each model (and alignments): >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.6 0.0 1.1e-12 2.4e-09 8 90 .] 34 121 .. 26 121 .. 0.78 2 ! 46.7 0.0 1.7e-15 3.6e-12 1 90 [] 176 264 .. 176 264 .. 0.94 3 ! 31.4 0.0 9.8e-11 2.1e-07 5 90 .] 278 379 .. 273 379 .. 0.71 Alignments for each domain: == domain 1 score: 37.6 bits; conditional E-value: 1.1e-12 I-set 8 kdvevkeGesaeleckvsGepepevs.....Wlkdgselke.skrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 + +v eG++++l c+v+G+ +p vs W+k + l ++ ++k + + L+I+nvk D G+Y c a n g+ + +++L V FUN_002093-T1 34 PQYTVIEGQTLKLRCEVTGTNDPPVSrtltaWKKLPEGLIIrDEFPRFKIRL-GKYLRIKNVKLGDRGTYVCSAWNPDGKLTRQIRLVV 121 5789********************9766666888844443314333333333.559**************************9999976 PP == domain 2 score: 46.7 bits; conditional E-value: 1.7e-15 I-set 1 pkftqkl.kdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p+ft+++ ++ + ++G++++l+c+v G+ +v+Wlk+g+ l + +r +k+++ L++++++++++G Y c ++n++g+ + + ++V FUN_002093-T1 176 PEFTNPSnRSSQYTQGSTIRLKCHVNGKLSFNVTWLKNGRRLGKAERKLLKSKG--RVLHFQKLSPSQAGFYMCIVENELGRIVKAFDVKV 264 6888888789999*******************************9999999999..9************************9999888887 PP == domain 3 score: 31.4 bits; conditional E-value: 9.8e-11 I-set 5 qklkdvevkeGesaeleckvsGepepev...sWlkdgselke....skrvkvkaee.........gtatLtIsnvkkeDeGkYtckatnsageaea 84 + lk+ +++ G++a++ c++ + p++ +W+ +s k sk ++++ + t++L+I+nv+++De kYtc+++nsag a+ FUN_002093-T1 278 KALKNETANSGDDATFVCSAVSKSYPDFnflKWKGPESVSKVnfriSKFREIREVAkpligrgrmYTHRLIIHNVTSADEAKYTCVVRNSAGWASR 373 5668888899999999999988888876112454444433335566333333333344455555689***************************** PP I-set 85 saeLtV 90 ++ LtV FUN_002093-T1 374 DVFLTV 379 ****98 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.7 0.0 1.4e-12 3e-09 1 78 [] 25 108 .. 25 108 .. 0.73 2 ! 43.8 0.0 1.8e-14 3.8e-11 2 78 .] 176 251 .. 176 251 .. 0.86 3 ! 32.5 0.0 5.8e-11 1.2e-07 1 78 [] 272 366 .. 272 366 .. 0.83 Alignments for each domain: == domain 1 score: 37.7 bits; conditional E-value: 1.4e-12 Ig_3 1 kPvit..vspsstvveegesvtLtCeaegnppptitWykngke.lssgstskr.....sssssnstLtisnvtredsGtYtCvAsN 78 +P+i v+p+ t v eg++++L+Ce++g++ p ++ + + l++g r + + L+i+nv+ d+GtY C A+N FUN_002093-T1 25 PPSIIgtVKPQYT-VIEGQTLKLRCEVTGTNDPPVSRTLTAWKkLPEGLII-RdefprFKIRLGKYLRIKNVKLGDRGTYVCSAWN 108 8999965555555.8************998888553333333212222222.23577789999999*******************9 PP == domain 2 score: 43.8 bits; conditional E-value: 1.8e-14 Ig_3 2 Pvitvspsstv.veegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 P++t +++ ++ ++g++++L+C+++g+ + ++tW+kng++l ++ +s++++L++++++++++G Y C+++N FUN_002093-T1 176 PEFTNPSNRSSqYTQGSTIRLKCHVNGKLSFNVTWLKNGRRLGKAERK--LLKSKGRVLHFQKLSPSQAGFYMCIVEN 251 8888777766679************999999*********94443223..589***********************99 PP == domain 3 score: 32.5 bits; conditional E-value: 5.8e-11 Ig_3 1 kPvit.vspsstvveegesvtLtCeaegnppptitWykngkelssgstskr...................sssssnstLtisnvtredsGtYtCvA 76 kP+i +++++++g+++t+ C+a +++ p++ ++k ++ +s sk + ++ +L+i+nvt d+ +YtCv+ FUN_002093-T1 272 KPRILdKALKNETANSGDDATFVCSAVSKSYPDFNFLKWKGP---ESVSKVnfriskfreirevakpligRGRMYTHRLIIHNVTSADEAKYTCVV 364 67777655566669************9999999999998885...23333334567889999*******99999********************** PP Ig_3 77 sN 78 +N FUN_002093-T1 365 RN 366 *9 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.6 0.0 1.7e-09 3.7e-06 1 76 [. 34 112 .. 34 116 .. 0.86 2 ! 33.2 0.0 3.3e-11 7e-08 6 75 .. 189 254 .. 184 258 .. 0.92 3 ! 24.9 0.0 1.3e-08 2.7e-05 2 75 .. 282 369 .. 281 375 .. 0.82 Alignments for each domain: == domain 1 score: 27.6 bits; conditional E-value: 1.7e-09 ig 1 ptvtvleGesatLtCsas.egspgpdvt...WskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggs 76 p++tv eG+++ L+C+++ +++p+++ t W+k + +i ++ ++ ++ + + l i nv++ d GtY C ++np+g+ FUN_002093-T1 34 PQYTVIEGQTLKLRCEVTgTNDPPVSRTltaWKKLPEGLIIRDE-FPRFKIRLGKYLRIKNVKLGDRGTYVCSAWNPDGK 112 689***************97777777663337777777777777.********************************996 PP == domain 2 score: 33.2 bits; conditional E-value: 3.3e-11 ig 6 leGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpgg 75 +G++++L C+++ g ++vtW k+g ++ ++ + ++ + l++++ ++++aG+Y+C v+n++g FUN_002093-T1 189 TQGSTIRLKCHVN-GKLSFNVTWLKNGRRLGKAER---KLLKSKGRVLHFQKLSPSQAGFYMCIVENELG 254 68***********.****************99999...77888888*********************987 PP == domain 3 score: 24.9 bits; conditional E-value: 1.3e-08 ig 2 tvtvleGesatLtCsasegspgpdv...tWskegktkieslk............vkedngrttqssllisnvteedaGtYtCvvnnpgg 75 + t++ G+ at+ Csa+ + + pd+ +W+ ++++ + + ++gr++++ l i nvt d+ YtCvv+n+ g FUN_002093-T1 282 NETANSGDDATFVCSAV-SKSYPDFnflKWKGPESVSKVNFRiskfreirevakPLIGRGRMYTHRLIIHNVTSADEAKYTCVVRNSAG 369 56899************.555555511257777777777777********99988899****************************866 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 3.4e-08 7.1e-05 7 73 .. 34 115 .. 26 121 .. 0.70 2 ! 38.6 0.0 6.2e-13 1.3e-09 8 69 .. 183 255 .. 176 264 .. 0.77 3 ! 18.8 0.0 9.7e-07 0.0021 11 70 .. 285 370 .. 273 379 .. 0.74 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 3.4e-08 Ig_2 7 sptvvtegesvtLtCsas..gnppak...ytwykdg..kvls.ssqn.......fft.snvsaedsGtYtCtarntkggkvsn 73 ++ +v eg++++L+C++ ++pp++ w k +++ + ++ +++ +nv + d+GtY C+a+n++g+ ++ FUN_002093-T1 34 PQYTVIEGQTLKLRCEVTgtNDPPVSrtlTAWKKLPegLIIRdEFPRfkirlgkYLRiKNVKLGDRGTYVCSAWNPDGK-LTR 115 448899**********997667777777777776443355555223344666665556******************954.444 PP == domain 2 score: 38.6 bits; conditional E-value: 6.2e-13 Ig_2 8 p..tvvtegesvtLtCsasgnppakytwykdg........kvlsssqn.fftsnvsaedsGtYtCtarntkgg 69 +++t+g++++L+C++ g+ ++tw k+g k l+s+ + ++ ++ s++++G Y C ++n+ g FUN_002093-T1 183 NrsSQYTQGSTIRLKCHVNGKLSFNVTWLKNGrrlgkaerKLLKSKGRvLHFQKLSPSQAGFYMCIVENELGR 255 23479****************88*********555554444444555577779***************97654 PP == domain 3 score: 18.8 bits; conditional E-value: 9.7e-07 Ig_2 11 vtegesvtLtCsas..gnppak.ytwykdg...................kvls.....ssqnfftsnvsaedsGtYtCtarntkggk 70 + g++ t+ Csa + p+ + ++w +++ k+l +++++++nv++ d YtC++rn++g FUN_002093-T1 285 ANSGDDATFVCSAVskSYPDFNfLKWKGPEsvskvnfriskfreirevaKPLIgrgrmYTHRLIIHNVTSADEAKYTCVVRNSAG-W 370 67899*******88567777777888888899999999998866654444444666555555788*****************774.3 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 3.1e-06 0.0065 6 108 .. 36 121 .. 31 122 .. 0.69 2 ! 6.9 0.1 0.0046 9.7 4 38 .. 184 215 .. 182 229 .. 0.83 3 ! 7.2 0.0 0.0037 7.8 75 99 .. 232 255 .. 224 265 .. 0.76 4 ! 12.6 0.0 7.8e-05 0.17 8 95 .. 285 367 .. 281 380 .. 0.57 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 3.1e-06 V-set 6 vtvaeGesvtLtCslsss..eseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevv 99 tv eG++++L+C+++ + + W + p+g li++ +rf++r l+i+n++l D GtY C+ ++ ++ FUN_002093-T1 36 YTVIEGQTLKLRCEVTGTndPPVSRTLTAWKKLPEG-----LIIRDEF--------PRFKIRL-----GKYLRIKNVKLGDRGTYVCS-AWNPDGK 112 578888888888877744134455566677777776.....5555533........3555555.....448*****************.7788888 PP V-set 100 fgkgtrLtV 108 +++rL V FUN_002093-T1 113 LTRQIRLVV 121 888888887 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0046 V-set 4 revtvaeGesvtLtCslssseseasqsvyWyrqpp 38 r+ + +G +++L+C+++ + s+ v+W + + FUN_002093-T1 184 RSSQYTQGSTIRLKCHVNGK---LSFNVTWLKNGR 215 6667789***********99...99*****99765 PP == domain 3 score: 7.2 bits; conditional E-value: 0.0037 V-set 75 ltiqnltlsDsGtYtCavipkgevv 99 l++q+l++s++G+Y C v +++ ++ FUN_002093-T1 232 LHFQKLSPSQAGFYMCIV-ENELGR 255 89**************94.555444 PP == domain 4 score: 12.6 bits; conditional E-value: 7.8e-05 V-set 8 vaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipk 95 + G ++t+ Cs s++ + + ++W ++ ++ ++ i +++ + +r+ + l i+n+t +D++ YtC+v+++ FUN_002093-T1 285 ANSGDDATFVCSAVSKSYPDFNFLKWKGPESVSKVNFRISKFRE---IREVAKPLIGRG--RMYTHRLIIHNVTSADEAKYTCVVRNS 367 56677777777555543445555555443333233333333333...222233344444..5566779****************7544 PP >> Ig_6 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.016 35 72 91 .. 86 105 .. 74 127 .. 0.85 2 ! 11.1 0.0 0.00017 0.36 24 93 .. 184 250 .. 174 261 .. 0.73 3 ? -4.0 0.0 8.2 1.8e+04 74 97 .. 346 367 .. 343 373 .. 0.70 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.016 Ig_6 72 knaLrfkpvkvndsGlYiCr 91 ++ Lr+k vk d G+Y+C FUN_002093-T1 86 GKYLRIKNVKLGDRGTYVCS 105 5789***************8 PP == domain 2 score: 11.1 bits; conditional E-value: 0.00017 Ig_6 24 ksqlsktqgse..lpcsgs.kdksdVqWyrqqkdgepleeikesspniileknaLrfkpvkvndsGlYiCrpr 93 +s tqgs l+c+ + k + +V W + +g l + +++ ++ ++ +L+f+ + +++G+Y+C ++ FUN_002093-T1 184 RSS-QYTQGSTirLKCHVNgKLSFNVTWLK---NGRRLGKAERKL--LKSKGRVLHFQKLSPSQAGFYMCIVE 250 333.23444443588988856667999975...777777777766..6779*******************854 PP == domain 3 score: -4.0 bits; conditional E-value: 8.2 Ig_6 74 aLrfkpvkvndsGlYiCrprirsp 97 L ++ v++ d Y C +r + FUN_002093-T1 346 RLIIHNVTSADEAKYTCVVRN--S 367 577777888888889998443..3 PP >> DUF6584 Family of unknown function (DUF6584) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.4 0.0 0.0056 12 47 98 .. 233 286 .. 225 300 .. 0.86 2 ? 0.9 0.0 0.26 5.6e+02 92 124 .. 308 340 .. 291 359 .. 0.83 3 ! 5.8 0.1 0.0085 18 77 163 .. 360 438 .. 350 444 .. 0.59 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0056 DUF6584 47 YyelgdlaeAGrywyLeedkdpeekka..vevfeksvnnspaqilraLkyrgdk 98 +++ +++AG y+ + e++ +++ka v+vf + ++ p+ +aLk + + FUN_002093-T1 233 HFQKLSPSQAGFYMCIVENELGRIVKAfdVKVFGMEREHKPRILDKALKNETAN 286 6777789********************777899999999999999999876655 PP == domain 2 score: 0.9 bits; conditional E-value: 0.26 DUF6584 92 LkyrgdksklkteyaekkLealreevkeklgee 124 Lk++g++s k ++ k+ ++re +k +g+ FUN_002093-T1 308 LKWKGPESVSKVNFRISKFREIREVAKPLIGRG 340 9*********************99887666665 PP == domain 3 score: 5.8 bits; conditional E-value: 0.0085 DUF6584 77 feksvnnspaqilraLkyrgdksklkteyaekkLealreevkeklgeevdesskaskekeeskketkdklvtlgclvvvlailalvv 163 + v+ns+ + r++ + d+++ e++ ++ree ++ +++e++ s+ +++++ +++ l+ ++c++vv ++++ ++ FUN_002093-T1 360 YTCVVRNSAGWASRDVFLTVDEKEY-----EREKPEVREEEHSTATKEPSISEAQFRKE---IPAQDFRLAAIICVAVVSLLIVSII 438 5556666666666666666666554.....33345677777777777777776544433...3344556777778888844433333 PP >> Ig_4 T-cell surface glycoprotein CD3 delta chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.055 1.2e+02 31 49 .. 88 106 .. 81 120 .. 0.76 2 ? 8.7 0.0 0.0017 3.6 3 48 .. 193 248 .. 191 263 .. 0.77 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.055 Ig_4 31 tldlgksiedprglYqCke 49 l+++++ +rg+Y+C+ FUN_002093-T1 88 YLRIKNVKLGDRGTYVCSA 106 67788888899******93 PP == domain 2 score: 8.7 bits; conditional E-value: 0.0017 Ig_4 3 kVlLtC..nsss.keitwlkdgkeikeskek.......tldlgksiedprglYqCk 48 ++ L+C n + ++twlk+g + ++++k l+ +k + + g Y+C FUN_002093-T1 193 TIRLKChvNGKLsFNVTWLKNGRRLGKAERKllkskgrVLHFQKLSPSQAGFYMCI 248 678999553333479*******9999998887766666778888888999999996 PP >> Orf78 Orf78 (ac78) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 6e-05 0.13 26 95 .. 382 452 .. 373 461 .. 0.53 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 6e-05 Orf78 26 daddndkaenkkekqsvaakneieekesnaekasalnillisllavvcv.lvllyviyYfvilrerrkssv 95 ++ + +k+e ++e++s+a+k+ + ++ + +++ a++ l ++++v +v l+++ +i ++i+r+r+ + + FUN_002093-T1 382 KEYEREKPEVREEEHSTATKEPSISEAQFRKEIPAQDFRLAAIICVAVVsLLIVSIIWCYFITRKRHCHEK 452 44455566665555555555544444333344445454444444443331344567777778888765544 PP >> Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 6.6 1.4e+04 85 96 .. 45 56 .. 41 64 .. 0.81 2 ? -0.0 0.0 0.75 1.6e+03 72 96 .. 88 112 .. 75 117 .. 0.85 3 ? 6.9 0.0 0.0051 11 68 97 .. 227 256 .. 180 260 .. 0.75 4 ? 1.0 0.0 0.36 7.6e+02 73 95 .. 347 369 .. 317 373 .. 0.81 5 ? -3.0 0.0 6.4 1.4e+04 18 42 .. 490 514 .. 481 522 .. 0.72 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 6.6 Zwei_Ig_N 85 kYrCeittedge 96 k rCe+t +++ FUN_002093-T1 45 KLRCEVTGTNDP 56 679999999985 PP == domain 2 score: -0.0 bits; conditional E-value: 0.75 Zwei_Ig_N 72 ylefgkatveeaGkYrCeittedge 96 yl++ ++++ + G Y C dg+ FUN_002093-T1 88 YLRIKNVKLGDRGTYVCSAWNPDGK 112 78889999999******98877776 PP == domain 3 score: 6.9 bits; conditional E-value: 0.0051 Zwei_Ig_N 68 ekraylefgkatveeaGkYrCeittedgel 97 +k +l+f k + ++aG Y+C ++ e g++ FUN_002093-T1 227 SKGRVLHFQKLSPSQAGFYMCIVENELGRI 256 345679***************999887765 PP == domain 4 score: 1.0 bits; conditional E-value: 0.36 Zwei_Ig_N 73 lefgkatveeaGkYrCeittedg 95 l ++++t ++ kY+C ++ + g FUN_002093-T1 347 LIIHNVTSADEAKYTCVVRNSAG 369 456788999999*****998766 PP == domain 5 score: -3.0 bits; conditional E-value: 6.4 Zwei_Ig_N 18 aksteekplkaevtdLWCqaeekge 42 +s ++ +++++++ W ++++++ FUN_002093-T1 490 LQSHPDESVSKATQKVWTAVTTTAS 514 5667777788889999988876665 PP >> SID-1_RNA_chan dsRNA-gated channel SID-1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.3 6e-05 0.13 79 168 .. 379 472 .. 363 524 .. 0.67 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6e-05 SID-1_RNA_chan 79 vkpddsacstslslkel....enrtkkltvtvkksieeesYvvallvvllvlllfvlvvllvlivkeirkeseesaelasseplasklsseeds 168 v ++++ ++ ++e +++ + + ++ k i +++ a +++++v+ l ++ ++ + +++++r+ +e+s++ ++ +++++ +++ FUN_002093-T1 379 VDEKEYEREKPEVREEEhstaTKEPSISEAQFRKEIPAQDFRLAAIICVAVVSLLIVSIIWCYFITRKRHCHEKSMNEQNAFRHHVDCNAQRHD 472 555555554444333333333455555677899***********************************96666665555444444434433332 PP >> TMEM154 TMEM154 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00022 0.47 41 103 .. 397 461 .. 378 484 .. 0.70 2 ? -2.5 0.0 2.7 5.7e+03 21 41 .. 497 516 .. 472 527 .. 0.56 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00022 TMEM154 41 kqeeakanlsstdldneedqlefil..mviiPlvlliilllvvvilitkykrkRaKddekseaes 103 + + + ++s++++ +e ++f l ++ + v l+i++++ + it++++ K ++++a FUN_002093-T1 397 STATKEPSISEAQFRKEIPAQDFRLaaIICVAVVSLLIVSIIWCYFITRKRHCHEKSMNEQNAFR 461 34566678899999999887777763366667788888888888899877777777665555443 PP == domain 2 score: -2.5 bits; conditional E-value: 2.7 TMEM154 21 tleeetataslaavteteslk 41 +++ t + +avt+t s+ FUN_002093-T1 497 SVSKATQKV-WTAVTTTASIS 516 333333333.33444443333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (530 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1191 (0.0466236); expected 510.9 (0.02) Passed bias filter: 932 (0.0364846); expected 510.9 (0.02) Passed Vit filter: 84 (0.00328831); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 5183.37 // Query: FUN_002094-T1 [L=160] Description: FUN_002094 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 487 (0.0190644); expected 510.9 (0.02) Passed bias filter: 423 (0.016559); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1599.50 // Query: FUN_002095-T1 [L=103] Description: FUN_002095 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.067 13.8 0.5 0.085 13.5 0.5 1.2 1 DUF7574 Domain of unknown function (DUF7574) Domain annotation for each model (and alignments): >> DUF7574 Domain of unknown function (DUF7574) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.5 3.3e-06 0.085 44 89 .. 48 93 .. 34 101 .. 0.87 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 3.3e-06 DUF7574 44 atDsGcSCpsPyedlksiedlekpltlaelrkklrrkledadlyet 89 +D cSCps + + ++i+ p+ + ++ +++ r+ a +y+t FUN_002095-T1 48 EHDRTCSCPSSWGHSRKIHAHPVPTRYYQIVDQVGRSRSSASSYNT 93 58999**************877799999999999999888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 829 (0.0324525); expected 510.9 (0.02) Passed bias filter: 379 (0.0148366); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1047.96 // Query: FUN_002096-T1 [L=160] Description: FUN_002096 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.074 13.5 0.0 0.16 12.4 0.0 1.5 1 Trm56 tRNA ribose 2'-O-methyltransferase, aTrm56 Domain annotation for each model (and alignments): >> Trm56 tRNA ribose 2'-O-methyltransferase, aTrm56 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 6.2e-06 0.16 38 92 .. 93 151 .. 87 156 .. 0.84 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 6.2e-06 Trm56 38 edvieeirkkekdllvvvGaekvpaevyeladynvavg....nqPhsEvaalavfldrl 92 +++i+ei++ +d ++vv +++++ e++ dy v + Ph + a a+ ldr FUN_002096-T1 93 SSAIDEINSVLEDGFIVVDGKQIEIEMFLEGDYTFLVMvmglSVPHLSIHACALKLDRC 151 67899****************************86654222357************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 803 (0.0314347); expected 510.9 (0.02) Passed bias filter: 768 (0.0300646); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.45s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1613.71 // Query: FUN_002097-T1 [L=66] Description: FUN_002097 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (66 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 273 (0.010687); expected 510.9 (0.02) Passed bias filter: 144 (0.00563711); expected 510.9 (0.02) Passed Vit filter: 9 (0.000352319); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.38s 00:00:00.59 Elapsed: 00:00:00.38 # Mc/sec: 691.22 // Query: FUN_002098-T1 [L=327] Description: FUN_002098 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-20 72.8 0.5 1.3e-09 38.9 0.0 2.9 2 Ig_3 Immunoglobulin domain 1.8e-18 66.9 0.0 1.2e-11 45.0 0.0 3.1 2 I-set Immunoglobulin I-set domain 8.7e-17 61.7 1.4 6e-08 33.4 0.0 3.2 2 ig Immunoglobulin domain 4.2e-11 43.4 2.0 2.1e-06 28.4 0.0 3.1 3 Ig_2 Immunoglobulin domain 7e-10 39.6 1.7 0.00044 20.9 0.0 3.2 3 V-set Immunoglobulin V-set domain ------ inclusion threshold ------ 0.011 16.5 0.0 0.59 11.0 0.0 2.8 3 C1-set Immunoglobulin C1-set domain 0.04 14.2 0.2 0.49 10.7 0.0 2.2 2 V-set_CD47 CD47 immunoglobulin-like domain 0.09 13.6 0.0 2.8 8.8 0.0 2.3 2 Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal 0.24 12.2 1.2 0.34 11.7 0.3 1.6 2 Chitin_bind_4 Insect cuticle protein Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.9 0.0 4.4e-13 1.3e-09 17 78 .] 12 72 .. 6 72 .. 0.85 2 ! 30.8 0.3 1.5e-10 4.3e-07 7 78 .] 99 189 .. 92 189 .. 0.84 Alignments for each domain: == domain 1 score: 38.9 bits; conditional E-value: 4.4e-13 Ig_3 17 esvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 sv+L+C+a+g+ p +++W+k+g+ +++ + ++ + +++ L+++++ + dsG+YtC +sN FUN_002098-T1 12 HSVRLKCKANGSTPLKFQWLKDGQAKIQRRLQP-RMRTDTWYLKLKDLAPLDSGKYTCLVSN 72 68*******888888*********855534333.88889999*******************9 PP == domain 2 score: 30.8 bits; conditional E-value: 1.5e-10 Ig_3 7 spsstvveegesvtLtCea.egnppptitWykngke.......lssgstskr................sssssnstLtisnvtredsGtYtCvAsN 78 p++t+v g++++LtC + ++ p+++W+k + + l + ++++ +++i+nvt + G YtC +sN FUN_002098-T1 99 YPRNTSVLLGQNASLTCVVvISGTLPDFRWLKWSAVpemypgaL-----NFQsgsyslvnprqyetvyVAGKYGVKVNIRNVTSKELGLYTCYVSN 189 588888*************9999999*********877544431.....222556678899999999999999999*******************9 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.0 0.0 4.2e-15 1.2e-11 16 90 .] 12 85 .. 4 85 .. 0.91 2 ! 15.8 0.1 5.3e-06 0.015 7 88 .. 100 200 .. 97 201 .. 0.75 Alignments for each domain: == domain 1 score: 45.0 bits; conditional E-value: 4.2e-15 I-set 16 esaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 s++l+ck+ G+ +++++Wlkdg+ ++r++ +++ +t L+++++ + D+GkYtc ++n +g+ +++ +L + FUN_002098-T1 12 HSVRLKCKANGSTPLKFQWLKDGQAKI-QRRLQPRMRTDTWYLKLKDLAPLDSGKYTCLVSNTYGSINHTYTLRI 85 589*******************77644.379999999999****************************9999975 PP == domain 2 score: 15.8 bits; conditional E-value: 5.3e-06 I-set 7 lkdvevkeGesaeleckvsGe.pepevsWlkdgselke................skrvkvkaee..gtatLtIsnvkkeDeGkYtckatnsageae 83 +++++v G++a+l+c v + p+++Wlk + ++++ + + + I+nv++++ G Ytc ++n +g + FUN_002098-T1 100 PRNTSVLLGQNASLTCVVVISgTLPDFRWLKWSAVPEMypgalnfqsgsyslvnPRQYETVYVAgkYGVKVNIRNVTSKELGLYTCYVSNHLGYDY 195 678888889999999976433247889998885554445678888878877777666666666634566889*********************988 PP I-set 84 asaeL 88 sa L FUN_002098-T1 196 RSAFL 200 88766 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.4 0.0 2.1e-11 6e-08 8 77 .. 11 77 .. 6 81 .. 0.90 2 ! 23.9 0.5 1.9e-08 5.3e-05 2 77 .. 102 194 .. 101 198 .. 0.84 Alignments for each domain: == domain 1 score: 33.4 bits; conditional E-value: 2.1e-11 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqs.sllisnvteedaGtYtCvvnnpggsa 77 +s++L C+a+ gs++ ++W k+g+ ki+ + + +++t++ l + + + d+G YtC v+n+ gs FUN_002098-T1 11 RHSVRLKCKAN-GSTPLKFQWLKDGQAKIQRRL---QPRMRTDTwYLKLKDLAPLDSGKYTCLVSNTYGSI 77 689********.*********************...777777777899******************98875 PP == domain 2 score: 23.9 bits; conditional E-value: 1.9e-08 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslk........vkedngrttqs.........sllisnvteedaGtYtCvvnnpggsa 77 ++ vl G++a LtC ++ + + pd+ W k +++ + n r++ + ++i+nvt + G YtC+v+n++g + FUN_002098-T1 102 NTSVLLGQNASLTCVVVISGTLPDFRWLKWSAVPEMYPGalnfqsgsYSLVNPRQYETvyvagkygvKVNIRNVTSKELGLYTCYVSNHLGYD 194 7899*************999*******9998888876666677888855555555555777799999**********************9865 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.4 0.0 7.2e-10 2.1e-06 13 69 .. 10 76 .. 3 86 .. 0.79 2 ! 13.0 0.2 4.4e-05 0.13 9 68 .. 103 192 .. 92 201 .. 0.70 3 ? -2.5 0.0 3.1 8.7e+03 47 67 .. 211 232 .. 194 239 .. 0.65 Alignments for each domain: == domain 1 score: 28.4 bits; conditional E-value: 7.2e-10 Ig_2 13 egesvtLtCsasgnppakytwykdg.....kvlsssqn....fft.snvsaedsGtYtCtarntkgg 69 ++sv+L+C+a g p k++w kdg + l+++++ ++ + + dsG YtC ++nt g+ FUN_002098-T1 10 ARHSVRLKCKANGSTPLKFQWLKDGqakiqRRLQPRMRtdtwYLKlKDLAPLDSGKYTCLVSNTYGS 76 5789*********999*********7755544446655777755557799*************8875 PP == domain 2 score: 13.0 bits; conditional E-value: 4.4e-05 Ig_2 9 tvvtegesvtLtCsas.gnppakytwykdg.................kvlsssqn............fftsnvsaedsGtYtCtarntkg 68 t v g++ +LtC + + ++++w k + + ++++q + ++nv++ G YtC+++n+ g FUN_002098-T1 103 TSVLLGQNASLTCVVViSGTLPDFRWLKWSavpemypgalnfqsgsySLVNPRQYetvyvagkygvkVNIRNVTSKELGLYTCYVSNHLG 192 556679999*****8864557********9888888877766666664444333356666666665555799***************654 PP == domain 3 score: -2.5 bits; conditional E-value: 3.1 Ig_2 47 ftsnvsaedsGt.YtCtarntk 67 ++ +v+ Y+++++n++ FUN_002098-T1 211 LSDTVTTKYPDQrYQAYPGNQG 232 4455554444444888888865 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.01 29 12 40 .. 12 37 .. 4 46 .. 0.85 2 ! 11.8 0.0 0.0001 0.3 64 108 .. 44 85 .. 33 86 .. 0.78 3 ! 20.9 0.0 1.6e-07 0.00044 3 94 .. 100 190 .. 98 200 .. 0.71 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.01 V-set 12 esvtLtCslssseseasqsvyWyrqppgk 40 +sv+L+C+ + s + +++W ++ + k FUN_002098-T1 12 HSVRLKCKANGS---TPLKFQWLKDGQAK 37 79********99...*********88765 PP == domain 2 score: 11.8 bits; conditional E-value: 0.0001 V-set 64 lrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 r+ + l++++l + DsG YtC +++ +++ +++++L++ FUN_002098-T1 44 PRM--RTDTWYLKLKDLAPLDSGKYTCL-VSNTYGSINHTYTLRI 85 555..6667789****************.7888888888888876 PP == domain 3 score: 20.9 bits; conditional E-value: 1.6e-07 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgk..epteliayysn.kseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCav.ip 94 pr ++v +G++++LtC++ s + +++W + ++ p l +++ + + ++++ +++ +++ + + ++i+n+t + G+YtC v ++ FUN_002098-T1 100 PRNTSVLLGQNASLTCVVVIS--GTLPDFRWLKWSAVPemYPGALNFQSGSySLVNPRQYETVYVAG---KYGVKVNIRNVTSKELGLYTCYVsNH 190 8999************55544..35555555555555422444444444446777888888888888...99********************8543 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 0.00021 0.59 13 83 .. 11 72 .. 7 74 .. 0.86 2 ? 1.9 0.0 0.15 4.2e+02 5 22 .. 100 117 .. 98 130 .. 0.82 3 ? -2.0 0.0 2.3 6.6e+03 75 83 .. 181 189 .. 169 195 .. 0.69 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00021 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqllskLtvtpsewesgdeytCkVeh 83 ++++ L C ++g P +k +Wlk+gq + + +p +++d y l+ L + +ytC V++ FUN_002098-T1 11 RHSVRLKCKANGSTP--LKFQWLKDGQAKIQ--RRLQPRMRTDTWYLKLKDLAPLD-----SGKYTCLVSN 72 577889999999988..99*********998..999999999****9999987666.....6679999976 PP == domain 2 score: 1.9 bits; conditional E-value: 0.15 C1-set 5 ppspeelkgkkntLvClv 22 p++++ l g++++L+C+v FUN_002098-T1 100 PRNTSVLLGQNASLTCVV 117 566666669*******98 PP == domain 3 score: -2.0 bits; conditional E-value: 2.3 C1-set 75 deytCkVeh 83 ytC V++ FUN_002098-T1 181 GLYTCYVSN 189 457777764 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.00017 0.49 50 104 .. 29 88 .. 8 93 .. 0.69 2 ? 1.0 0.1 0.18 5e+02 77 88 .. 178 189 .. 152 193 .. 0.81 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00017 V-set_CD47 50 kWkfnnkdifisnktekkst....Lkldfsdal.sGnYtCevtelsnevkttieLklvvk 104 +W +++ ++ + ++ t Lkl+ l sG YtC v+++ ++++t L++v+k FUN_002098-T1 29 QWLKDGQAKIQRRLQPRMRTdtwyLKLKDLAPLdSGKYTCLVSNTYGSINHTYTLRIVEK 88 55555554444333333322455588877666658********************99876 PP == domain 2 score: 1.0 bits; conditional E-value: 0.18 V-set_CD47 77 alsGnYtCevte 88 + G YtC+v++ FUN_002098-T1 178 KELGLYTCYVSN 189 45799****987 PP >> Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 0.0 0.00099 2.8 35 96 .. 18 76 .. 9 83 .. 0.75 2 ? 2.4 0.0 0.097 2.7e+02 49 91 .. 146 188 .. 131 195 .. 0.69 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00099 Zwei_Ig_N 35 CqaeekgekllpiksarfvrkkdkkvleakisnekraylefgkatveeaGkYrCeittedge 96 C+a+ g++ l+ ++ + ++k ++ l+ +++++ yl++ + ++GkY+C + + g+ FUN_002098-T1 18 CKAN--GSTPLKFQWLKDGQAKIQRRLQPRMRTD-TWYLKLKDLAPLDSGKYTCLVSNTYGS 76 5554..4555666666666777777777788888.889****************99887765 PP == domain 2 score: 2.4 bits; conditional E-value: 0.097 Zwei_Ig_N 49 sarfvrkkdkkvleakisnekraylefgkatveeaGkYrCeit 91 s+++ +++++ + + + +++++ ++t +e G Y+C + FUN_002098-T1 146 SGSYSLVNPRQYETVYVAGKYGVKVNIRNVTSKELGLYTCYVS 188 5555555555555555555556778888999999999999886 PP >> Chitin_bind_4 Insect cuticle protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.3 0.00012 0.34 32 59 .. 146 171 .. 140 176 .. 0.83 2 ? -3.7 0.0 7.6 2.2e+04 49 58 .. 186 195 .. 184 201 .. 0.72 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00012 Chitin_bind_4 32 kGsYsyvdpdGrtvrvvYtADenGFrae 59 +GsYs+v+p ++++vY+A++ G +++ FUN_002098-T1 146 SGSYSLVNPR--QYETVYVAGKYGVKVN 171 8********7..59*******9986655 PP == domain 2 score: -3.7 bits; conditional E-value: 7.6 Chitin_bind_4 49 YtADenGFra 58 Y++++ G+ FUN_002098-T1 186 YVSNHLGYDY 195 8888888865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (327 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 558 (0.0218438); expected 510.9 (0.02) Passed bias filter: 494 (0.0193384); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.34u 0.42s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 3205.41 // Query: FUN_002098-T2 [L=298] Description: FUN_002098 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-20 73.3 0.6 1.1e-09 39.1 0.0 2.9 2 Ig_3 Immunoglobulin domain 1.2e-18 67.5 0.0 1e-11 45.2 0.0 3.2 2 I-set Immunoglobulin I-set domain 5.3e-17 62.4 1.4 5.1e-08 33.6 0.0 3.3 2 ig Immunoglobulin domain 5.2e-11 43.1 3.4 1.7e-06 28.6 0.0 3.4 4 Ig_2 Immunoglobulin domain 4.2e-10 40.3 1.7 0.00037 21.1 0.0 3.3 3 V-set Immunoglobulin V-set domain 0.0076 17.0 0.0 0.51 11.2 0.0 2.9 3 C1-set Immunoglobulin C1-set domain ------ inclusion threshold ------ 0.018 15.9 0.1 2.4 9.0 0.0 3.0 3 Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal 0.032 14.5 0.1 0.41 10.9 0.0 2.2 2 V-set_CD47 CD47 immunoglobulin-like domain 0.16 12.7 0.9 0.28 12.0 0.3 1.6 2 Chitin_bind_4 Insect cuticle protein Domain annotation for each model (and alignments): >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 0.0 3.8e-13 1.1e-09 17 78 .] 12 72 .. 6 72 .. 0.85 2 ! 31.0 0.3 1.3e-10 3.7e-07 7 78 .] 99 189 .. 92 189 .. 0.84 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 3.8e-13 Ig_3 17 esvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 sv+L+C+a+g+ p +++W+k+g+ +++ + ++ + +++ L+++++ + dsG+YtC +sN FUN_002098-T2 12 HSVRLKCKANGSTPLKFQWLKDGQAKIQRRLQP-RMRTDTWYLKLKDLAPLDSGKYTCLVSN 72 68*******888888*********855534333.88889999*******************9 PP == domain 2 score: 31.0 bits; conditional E-value: 1.3e-10 Ig_3 7 spsstvveegesvtLtCea.egnppptitWykngke.......lssgstskr................sssssnstLtisnvtredsGtYtCvAsN 78 p++t+v g++++LtC + ++ p+++W+k + + l + ++++ +++i+nvt + G YtC +sN FUN_002098-T2 99 YPRNTSVLLGQNASLTCVVvISGTLPDFRWLKWSAVpemypgaL-----NFQsgsyslvnprqyetvyVAGKYGVKVNIRNVTSKELGLYTCYVSN 189 588888*************9999999*********877544431.....222556678899999999999999999*******************9 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.2 0.0 3.6e-15 1e-11 16 90 .] 12 85 .. 4 85 .. 0.91 2 ! 16.1 0.1 4.4e-06 0.012 7 88 .. 100 200 .. 97 201 .. 0.75 Alignments for each domain: == domain 1 score: 45.2 bits; conditional E-value: 3.6e-15 I-set 16 esaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 s++l+ck+ G+ +++++Wlkdg+ ++r++ +++ +t L+++++ + D+GkYtc ++n +g+ +++ +L + FUN_002098-T2 12 HSVRLKCKANGSTPLKFQWLKDGQAKI-QRRLQPRMRTDTWYLKLKDLAPLDSGKYTCLVSNTYGSINHTYTLRI 85 589*******************77644.379999999999****************************9999975 PP == domain 2 score: 16.1 bits; conditional E-value: 4.4e-06 I-set 7 lkdvevkeGesaeleckvsGe.pepevsWlkdgselke................skrvkvkaee..gtatLtIsnvkkeDeGkYtckatnsageae 83 +++++v G++a+l+c v + p+++Wlk + ++++ + + + I+nv++++ G Ytc ++n +g + FUN_002098-T2 100 PRNTSVLLGQNASLTCVVVISgTLPDFRWLKWSAVPEMypgalnfqsgsyslvnPRQYETVYVAgkYGVKVNIRNVTSKELGLYTCYVSNHLGYDY 195 678888889999999976433247889998885555445678888878887777666666666634566889*********************988 PP I-set 84 asaeL 88 sa L FUN_002098-T2 196 RSAFL 200 88766 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.6 0.0 1.8e-11 5.1e-08 8 77 .. 11 77 .. 6 81 .. 0.90 2 ! 24.2 0.5 1.5e-08 4.4e-05 2 77 .. 102 194 .. 101 198 .. 0.84 Alignments for each domain: == domain 1 score: 33.6 bits; conditional E-value: 1.8e-11 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqs.sllisnvteedaGtYtCvvnnpggsa 77 +s++L C+a+ gs++ ++W k+g+ ki+ + + +++t++ l + + + d+G YtC v+n+ gs FUN_002098-T2 11 RHSVRLKCKAN-GSTPLKFQWLKDGQAKIQRRL---QPRMRTDTwYLKLKDLAPLDSGKYTCLVSNTYGSI 77 689********.*********************...777777777899******************98875 PP == domain 2 score: 24.2 bits; conditional E-value: 1.5e-08 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslk........vkedngrttqs.........sllisnvteedaGtYtCvvnnpggsa 77 ++ vl G++a LtC ++ + + pd+ W k +++ + n r++ + ++i+nvt + G YtC+v+n++g + FUN_002098-T2 102 NTSVLLGQNASLTCVVVISGTLPDFRWLKWSAVPEMYPGalnfqsgsYSLVNPRQYETvyvagkygvKVNIRNVTSKELGLYTCYVSNHLGYD 194 7899*************999*******9998888876666677888855555555555777799999**********************9865 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.6 0.0 6.1e-10 1.7e-06 13 69 .. 10 76 .. 3 86 .. 0.79 2 ! 13.3 0.2 3.7e-05 0.1 9 68 .. 103 192 .. 92 201 .. 0.70 3 ? -2.2 0.0 2.5 7.2e+03 49 68 .. 213 233 .. 197 242 .. 0.64 4 ? -4.1 0.0 9 2.6e+04 18 23 .. 277 282 .. 272 288 .. 0.74 Alignments for each domain: == domain 1 score: 28.6 bits; conditional E-value: 6.1e-10 Ig_2 13 egesvtLtCsasgnppakytwykdg.....kvlsssqn....fft.snvsaedsGtYtCtarntkgg 69 ++sv+L+C+a g p k++w kdg + l+++++ ++ + + dsG YtC ++nt g+ FUN_002098-T2 10 ARHSVRLKCKANGSTPLKFQWLKDGqakiqRRLQPRMRtdtwYLKlKDLAPLDSGKYTCLVSNTYGS 76 5789*********999*********7755544446655777755557799*************8875 PP == domain 2 score: 13.3 bits; conditional E-value: 3.7e-05 Ig_2 9 tvvtegesvtLtCsas.gnppakytwykdg.................kvlsssqn............fftsnvsaedsGtYtCtarntkg 68 t v g++ +LtC + + ++++w k + + ++++q + ++nv++ G YtC+++n+ g FUN_002098-T2 103 TSVLLGQNASLTCVVViSGTLPDFRWLKWSavpemypgalnfqsgsySLVNPRQYetvyvagkygvkVNIRNVTSKELGLYTCYVSNHLG 192 556679999*****8864557********9888888877766666664444333356666666665555799***************654 PP == domain 3 score: -2.2 bits; conditional E-value: 2.5 Ig_2 49 snvsaedsGt.YtCtarntkg 68 +v+ Y+++++n+++ FUN_002098-T2 213 DTVTTKYPDQrYQAYPGNQGT 233 455544444448888888654 PP == domain 4 score: -4.1 bits; conditional E-value: 9 Ig_2 18 tLtCsa 23 L+C+ FUN_002098-T2 277 LLWCHF 282 589994 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.6 0.0 0.009 25 12 40 .. 12 37 .. 4 46 .. 0.85 2 ! 12.0 0.0 9.1e-05 0.26 64 108 .. 44 85 .. 33 86 .. 0.78 3 ! 21.1 0.0 1.3e-07 0.00037 3 94 .. 100 190 .. 98 200 .. 0.71 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.009 V-set 12 esvtLtCslssseseasqsvyWyrqppgk 40 +sv+L+C+ + s + +++W ++ + k FUN_002098-T2 12 HSVRLKCKANGS---TPLKFQWLKDGQAK 37 79********99...*********88765 PP == domain 2 score: 12.0 bits; conditional E-value: 9.1e-05 V-set 64 lrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 r+ + l++++l + DsG YtC +++ +++ +++++L++ FUN_002098-T2 44 PRM--RTDTWYLKLKDLAPLDSGKYTCL-VSNTYGSINHTYTLRI 85 555..6667789****************.7888888888888876 PP == domain 3 score: 21.1 bits; conditional E-value: 1.3e-07 V-set 3 prevtvaeGesvtLtCslssseseasqsvyWyrqppgk..epteliayysn.kseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCav.ip 94 pr ++v +G++++LtC++ s + +++W + ++ p l +++ + + ++++ +++ +++ + + ++i+n+t + G+YtC v ++ FUN_002098-T2 100 PRNTSVLLGQNASLTCVVVIS--GTLPDFRWLKWSAVPemYPGALNFQSGSySLVNPRQYETVYVAG---KYGVKVNIRNVTSKELGLYTCYVsNH 190 8999************55544..35555555555555422444444444446777888888888888...99********************8543 PP >> C1-set Immunoglobulin C1-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.0 0.00018 0.51 13 83 .. 11 72 .. 7 74 .. 0.86 2 ? 2.0 0.0 0.13 3.7e+02 5 22 .. 100 117 .. 98 130 .. 0.82 3 ? -1.1 0.0 1.3 3.6e+03 76 83 .. 182 189 .. 168 227 .. 0.71 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00018 C1-set 13 gkkntLvClvtgfyPpdikVtWlkngqevtegvkttdpvknsdstyqllskLtvtpsewesgdeytCkVeh 83 ++++ L C ++g P +k +Wlk+gq + + +p +++d y l+ L + +ytC V++ FUN_002098-T2 11 RHSVRLKCKANGSTP--LKFQWLKDGQAKIQ--RRLQPRMRTDTWYLKLKDLAPLD-----SGKYTCLVSN 72 577889999999988..99*********998..999999999****9999987666.....6679999976 PP == domain 2 score: 2.0 bits; conditional E-value: 0.13 C1-set 5 ppspeelkgkkntLvClv 22 p++++ l g++++L+C+v FUN_002098-T2 100 PRNTSVLLGQNASLTCVV 117 566666669*******98 PP == domain 3 score: -1.1 bits; conditional E-value: 1.3 C1-set 76 eytCkVeh 83 ytC V++ FUN_002098-T2 182 LYTCYVSN 189 46665543 PP >> Zwei_Ig_N Zwei immunoglobulin domain protein, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 0.0 0.00085 2.4 35 96 .. 18 76 .. 9 83 .. 0.75 2 ? 2.6 0.0 0.084 2.4e+02 49 91 .. 146 188 .. 131 195 .. 0.69 3 ? -0.2 0.0 0.66 1.9e+03 31 46 .. 276 291 .. 272 296 .. 0.73 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.00085 Zwei_Ig_N 35 CqaeekgekllpiksarfvrkkdkkvleakisnekraylefgkatveeaGkYrCeittedge 96 C+a+ g++ l+ ++ + ++k ++ l+ +++++ yl++ + ++GkY+C + + g+ FUN_002098-T2 18 CKAN--GSTPLKFQWLKDGQAKIQRRLQPRMRTD-TWYLKLKDLAPLDSGKYTCLVSNTYGS 76 5554..4555667776667777777777788888.889****************99887765 PP == domain 2 score: 2.6 bits; conditional E-value: 0.084 Zwei_Ig_N 49 sarfvrkkdkkvleakisnekraylefgkatveeaGkYrCeit 91 s+++ +++++ + + + +++++ ++t +e G Y+C + FUN_002098-T2 146 SGSYSLVNPRQYETVYVAGKYGVKVNIRNVTSKELGLYTCYVS 188 5555555555555555555556778888999999999999886 PP == domain 3 score: -0.2 bits; conditional E-value: 0.66 Zwei_Ig_N 31 tdLWCqaeekgekllp 46 LWC +k+++ l+ FUN_002098-T2 276 ALLWCHFFHKKQRSLR 291 569**99988887655 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 0.00015 0.41 50 104 .. 29 88 .. 6 93 .. 0.69 2 ? 1.2 0.1 0.15 4.4e+02 77 88 .. 178 189 .. 151 193 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00015 V-set_CD47 50 kWkfnnkdifisnktekkst....Lkldfsdal.sGnYtCevtelsnevkttieLklvvk 104 +W +++ ++ + ++ t Lkl+ l sG YtC v+++ ++++t L++v+k FUN_002098-T2 29 QWLKDGQAKIQRRLQPRMRTdtwyLKLKDLAPLdSGKYTCLVSNTYGSINHTYTLRIVEK 88 55555554444333333332455588877666658********************99876 PP == domain 2 score: 1.2 bits; conditional E-value: 0.15 V-set_CD47 77 alsGnYtCevte 88 + G YtC+v++ FUN_002098-T2 178 KELGLYTCYVSN 189 45799****987 PP >> Chitin_bind_4 Insect cuticle protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.3 9.8e-05 0.28 32 59 .. 146 171 .. 140 177 .. 0.83 2 ? -3.2 0.0 5.5 1.6e+04 49 60 .. 186 197 .. 184 202 .. 0.71 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 9.8e-05 Chitin_bind_4 32 kGsYsyvdpdGrtvrvvYtADenGFrae 59 +GsYs+v+p ++++vY+A++ G +++ FUN_002098-T2 146 SGSYSLVNPR--QYETVYVAGKYGVKVN 171 8********7..59*******9986665 PP == domain 2 score: -3.2 bits; conditional E-value: 5.5 Chitin_bind_4 49 YtADenGFraeg 60 Y++++ G+ + FUN_002098-T2 186 YVSNHLGYDYRS 197 888888986655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (298 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 695 (0.0272069); expected 510.9 (0.02) Passed bias filter: 582 (0.0227833); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 2976.97 // Query: FUN_002099-T1 [L=134] Description: FUN_002099 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.073 13.6 0.0 0.18 12.4 0.0 1.6 2 ASFV_P17 African swine fever virus minor capsid protein p17 Domain annotation for each model (and alignments): >> ASFV_P17 African swine fever virus minor capsid protein p17 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 0.2 5.1e+03 77 102 .. 44 69 .. 36 76 .. 0.69 2 ? 12.4 0.0 6.9e-06 0.18 59 95 .. 87 122 .. 82 131 .. 0.88 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 0.2 ASFV_P17 77 yyvqqpephhhfpvffrkrknstslq 102 y +ph ++ f++ k+ l+ FUN_002099-T1 44 YLTVSADPHVQLVSTFQNVKENKLLR 69 44556778888877777777766555 PP == domain 2 score: 12.4 bits; conditional E-value: 6.9e-06 ASFV_P17 59 yynrsvdckssmpkpppsyyvqqpephhhfpvffrkr 95 ynr v+ k++m + v+qp+p+h p++++k FUN_002099-T1 87 EYNR-VESKTTMKTSNSTIEVNQPQPKHLKPILWKKI 122 5777.89**************************9985 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 906 (0.0354668); expected 510.9 (0.02) Passed bias filter: 378 (0.0147974); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1337.59 // Query: FUN_002100-T1 [L=189] Description: FUN_002100 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-47 161.5 0.0 4.2e-47 161.1 0.0 1.1 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 1.3e-15 58.0 0.0 1.4e-15 57.9 0.0 1.1 1 Pkinase Protein kinase domain ------ inclusion threshold ------ 0.079 12.6 0.0 0.11 12.1 0.0 1.1 1 TCAD9 Ternary complex associated domain 9 0.23 11.0 0.0 0.33 10.6 0.0 1.1 1 ABC1 ABC1 atypical kinase-like domain Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 161.1 0.0 6.6e-51 4.2e-47 121 234 .. 28 141 .. 25 147 .. 0.98 Alignments for each domain: == domain 1 score: 161.1 bits; conditional E-value: 6.6e-51 PK_Tyr_Ser-Thr 121 kklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekkftsksDvWsfGvllwEiftlgeepykglkneevle 215 +++HrdlaarN+Lv e+ ++ki+DfGLar++++ dyy+k++k++lpikW+a+E+l ++++t +sDvW+fGvllwEift+g +py+g+ +++++ FUN_002100-T1 28 THCIHRDLAARNILVGEDYIMKIADFGLARSLRNMDYYRKTTKGRLPIKWLAIEALFDRVYTIQSDVWAFGVLLWEIFTFGGSPYPGIPVQNLFD 122 69********************************************************************************************* PP PK_Tyr_Ser-Thr 216 lleegerleqpencpeely 234 lle+g+r+e+p+ncp++++ FUN_002100-T1 123 LLESGYRMERPSNCPNNIT 141 ****************987 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.9 0.0 2.2e-19 1.4e-15 115 202 .. 26 117 .. 24 182 .. 0.87 Alignments for each domain: == domain 1 score: 57.9 bits; conditional E-value: 2.2e-19 Pkinase 115 HsegvvHrDlKpeNiLidekgelKitDFGlakelesssk...ltsfvgtseYmAPEvlkskkygkkvDvWslGvilyellt.gkppfsaeke 202 H +++HrDl NiL+ e+ +Ki+DFGla+ l++ +t+ +++A E l ++ y+ ++DvW+ Gv+l+e++t g +p+++ FUN_002100-T1 26 HVTHCIHRDLAARNILVGEDYIMKIADFGLARSLRNMDYyrkTTKGRLPIKWLAIEALFDRVYTIQSDVWAFGVLLWEIFTfGGSPYPGIPV 117 8899**************9999*************988776567777788****************************97537778775554 PP >> TCAD9 Ternary complex associated domain 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 1.7e-05 0.11 281 314 .. 12 45 .. 4 58 .. 0.87 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 1.7e-05 TCAD9 281 faalreaLtealearvtasvHGDLNprNvLlaed 314 f++ ++ L++ +++vt +H DL +rN+L+ ed FUN_002100-T1 12 FTFSEQDLSQYGQDHVTHCIHRDLAARNILVGED 45 667788999999*******************976 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 5.2e-05 0.33 186 220 .. 27 61 .. 19 71 .. 0.88 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 5.2e-05 ABC1 186 edgffhaDphpGNllvrkdgelvllDfGlmgelde 220 +++++h D+ + N+lv +d + + DfGl ++l++ FUN_002100-T1 27 VTHCIHRDLAARNILVGEDYIMKIADFGLARSLRN 61 5789**************************99865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (189 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 401 (0.0156978); expected 510.9 (0.02) Passed bias filter: 376 (0.0147191); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1887.90 // Query: FUN_002101-T1 [L=184] Description: FUN_002101 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 16.0 0.7 0.91 10.1 0.1 2.2 2 NleF_casp_inhib NleF caspase inhibitor 0.15 12.1 3.6 0.21 11.7 3.6 1.1 1 Peptidase_S30 Potyvirus P1 protease 0.19 12.7 0.2 0.44 11.5 0.2 1.6 1 HH_AAEA_pHBA pHBA AAEA subunit, alpha-helical hairpin dom 0.2 12.7 0.4 0.43 11.6 0.4 1.5 1 STPPase_N Serine-threonine protein phosphatase N-termi 1.1 9.9 7.8 1.5 9.4 7.8 1.2 1 CCD97-like_C Coiled-coil domain containing protein 97-lik 1.4 8.3 4.7 2.4 7.5 4.7 1.3 1 SDA1_HEAT SDA1, HEAT repeat 1.7 9.5 9.1 2.1 9.2 9.1 1.1 1 Dsh_C Segment polarity protein dishevelled (Dsh) C 3.6 6.2 8.5 4.5 5.9 8.5 1.0 1 CDC45 CDC45 Domain annotation for each model (and alignments): >> NleF_casp_inhib NleF caspase inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.1 0.00028 0.91 33 72 .. 82 118 .. 67 123 .. 0.76 2 ? 4.4 0.0 0.016 51 1 31 [. 136 166 .. 136 172 .. 0.90 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00028 NleF_casp_inhib 33 aekkikElsdkltklknsvlseredlYevvedykleggqk 72 +++ + E +++++l + ++s r dlY+ + kle+ + FUN_002101-T1 82 SKNILSE--EEIEELCERLESMRHDLYCE-IARKLESSSN 118 4455556..8999999999999******9.7777877665 PP == domain 2 score: 4.4 bits; conditional E-value: 0.016 NleF_casp_inhib 1 nknkiteetektlkdIksklkvifereisst 31 +kn ++e t++++++ ++++++ ++ t FUN_002101-T1 136 DKNVLNEITDEFVDEFTGVIHDVYHTKMTAT 166 79**********************9998765 PP >> Peptidase_S30 Potyvirus P1 protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 3.6 6.6e-05 0.21 41 116 .. 23 98 .. 6 104 .. 0.69 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 6.6e-05 Peptidase_S30 41 rekekreereerqflqlaaasivskitvkttekvsktesvsfrtk.lkkrttkkmkkkkkkkkvkmsakinkllrqv 116 +e ee++ + ++ +++++s+ +++e +++e+ ++ ++ +++ k++kk+k+ k++ ++i +l++++ FUN_002101-T1 23 IESSISEEDKLEG-ENNSDQDQTSSSCSESGEISKSGEAREKGKPrATTSVKKSSKKRKASKNILSEEEIEELCERL 98 4444444444444.4666777777777778888888888899999677777777777777777777777*****998 PP >> HH_AAEA_pHBA pHBA AAEA subunit, alpha-helical hairpin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.2 0.00014 0.44 26 59 .. 73 106 .. 65 113 .. 0.87 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00014 HH_AAEA_pHBA 26 rEagRRnrlgvqaiSreeieqanndlqtaehqLa 59 ++++++ + + +++S+eeie +l+ ++h L FUN_002101-T1 73 KKSSKKRKASKNILSEEEIEELCERLESMRHDLY 106 67889999***********************996 PP >> STPPase_N Serine-threonine protein phosphatase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.4 0.00013 0.43 13 32 .. 74 96 .. 69 97 .. 0.76 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00013 STPPase_N 13 g...kpggkkvqLsesEIraLCa 32 + k++ +k Lse+EI LC FUN_002101-T1 74 KsskKRKASKNILSEEEIEELCE 96 544466777888**********7 PP >> CCD97-like_C Coiled-coil domain containing protein 97-like, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 7.8 0.00047 1.5 88 155 .. 28 101 .. 4 106 .. 0.50 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00047 CCD97-like_C 88 eeeeeeeeeeeeeeeeeeeesekeee.........eeeeaeeekk....eeeeeekkekekekealseeereelreeftsi 155 ee++ e e++++++++ ++++ e +e+ k ++ ++++k+++++k+ lseee eel e+++s+ FUN_002101-T1 28 SEEDKLEGENNSDQDQTSSSCS---EsgeisksgeAREKG----KpratTSVKKSSKKRKASKNILSEEEIEELCERLESM 101 1111111111111111111111...123344333222222....233346778888888999999***********99876 PP >> SDA1_HEAT SDA1, HEAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 4.7 0.00075 2.4 168 221 .. 31 84 .. 18 102 .. 0.79 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.00075 SDA1_HEAT 168 aedessddedskkdlkklklklkinkktkkrekklekakkklkkkkkkkkkaek 221 + e ++++d++++ ++ + + +i+k + rek +a++++kk++kk+k++++ FUN_002101-T1 31 DKLEGENNSDQDQTSSSCSESGEISKSGEAREKGKPRATTSVKKSSKKRKASKN 84 333445555555789999**************************9999885554 PP >> Dsh_C Segment polarity protein dishevelled (Dsh) C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.2 9.1 0.00066 2.1 77 140 .. 21 84 .. 11 124 .. 0.68 Alignments for each domain: == domain 1 score: 9.2 bits; conditional E-value: 0.00066 Dsh_C 77 rssgsnrsegerrrkakeeekeakggsgsesesstrsglrrereaaqssrssaaasershrslk 140 s s+ se+++ + ++++++++ ++s+ses + ++sg re+ + +s + +s++ ++s++ FUN_002101-T1 21 SSIESSISEEDKLEGENNSDQDQTSSSCSESGEISKSGEAREKGKPRATTSVKKSSKKRKASKN 84 3445666777767777777777779*******99999997777766666665555555544433 PP >> CDC45 CDC45 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 8.5 0.0014 4.5 138 233 .. 25 119 .. 4 124 .. 0.46 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0014 CDC45 138 eeeeddeeeeeeeeeeedeeeeeedeeeskkkrksesdeeee.eeddeeersrkrrrseesakklrkqlkkerreyeavlekyYsqgtsygesvss 232 ++ +ee++ e e+++d+++++++ +es++ +ks +++e+ +++++ ++++++r+ +++ ++++ +++ ++ e+ ++ Y + es+s FUN_002101-T1 25 SS--ISEEDKLEGENNSDQDQTSSSCSESGEISKSGEAREKGkPRATTSVKKSSKKRKASKNILSEEEIEELCERLESMRHDLYCEIARKLESSSN 118 11..11222222233333333333333333333333333333433344444444444442344455557777788888888888877777777776 PP CDC45 233 l 233 + FUN_002101-T1 119 I 119 6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2166 (0.0847915); expected 510.9 (0.02) Passed bias filter: 1030 (0.040321); expected 510.9 (0.02) Passed Vit filter: 107 (0.00418869); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 1786.50 // Query: FUN_002102-T1 [L=857] Description: FUN_002102 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-94 316.0 0.0 3.4e-94 315.5 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 3e-44 149.5 0.0 7.7e-19 68.0 0.0 4.3 3 I-set Immunoglobulin I-set domain 2.1e-39 134.3 0.9 4.8e-14 53.1 0.0 4.4 4 Ig_3 Immunoglobulin domain 1.8e-37 129.7 0.0 2.7e-37 129.1 0.0 1.2 1 Pkinase Protein kinase domain 4.7e-27 94.6 0.3 2.3e-07 31.5 0.0 3.8 3 ig Immunoglobulin domain 2.6e-26 92.1 2.1 1.4e-10 41.7 0.0 4.0 3 Ig_2 Immunoglobulin domain 6.6e-18 65.4 3.5 1e-05 26.2 0.0 5.1 4 V-set Immunoglobulin V-set domain 3.7e-05 24.2 0.0 0.024 15.1 0.0 3.0 2 C2-set_2 CD80-like C2-set immunoglobulin domain 9.8e-05 22.7 0.0 0.0097 16.3 0.0 2.8 3 C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C 0.00035 20.8 0.0 2.9 8.2 0.0 3.3 3 V-set_CD47 CD47 immunoglobulin-like domain 0.0028 18.5 0.0 1.3 10.0 0.0 3.6 3 Ig_5 Ig-like domain on T-cell surface glycoprotein ------ inclusion threshold ------ 0.022 15.3 0.0 86 3.8 0.0 3.5 3 Ig_C17orf99 C17orf99 Ig domain 0.14 11.7 0.0 7.4 6.0 0.0 2.2 2 Haspin_kinase Haspin like kinase domain Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 315.5 0.0 1.7e-97 3.4e-94 1 256 [. 537 808 .. 537 810 .. 0.98 Alignments for each domain: == domain 1 score: 315.5 bits; conditional E-value: 1.7e-97 PK_Tyr_Ser-Thr 1 lelkeklGeGafGeVykgtlke.ekekkkikVavKtlkeeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLr 93 l++ e+lGeGafG V+++ + + + ++ +VavK+lk++a+e+e +++l+e+++mk++ +h+ni++l+g+ct+++pl++v+e+++ G+L++fLr FUN_002102-T1 537 LTIREQLGEGAFGLVMRADAVGlPDMPTTNSVAVKMLKADATENELADLLSEMDTMKEIgKHKNIINLIGACTQNGPLFVVVEFAPFGNLRQFLR 631 57899****************987888999***************************************************************** PP PK_Tyr_Ser-Thr 94 kk..............keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapE 174 ++ ++l++++ +++a qiA+GmeyL kk+vHrdlaarN+Lv e+ v+ki+DfGLar+v++ +yy+k+++++lpikW+a+E FUN_002102-T1 632 ERrpseyqqakssgsgGSSLTIRDFVSFAFQIARGMEYLGTKKCVHRDLAARNILVGEDYVMKIADFGLARNVRDLEYYRKTTDGRLPIKWLAIE 726 *********************************************************************************************** PP PK_Tyr_Ser-Thr 175 slkekkftsksDvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelve 256 +l ++++t++sDvW+fG+llwEiftlg +py+g+ e+++ell++g+r+++p+ncp+++y++m +Cw+e++++R +f++l++ FUN_002102-T1 727 ALFDRVYTTQSDVWAFGILLWEIFTLGGSPYPGIPIEKLFELLKSGYRMQKPQNCPNDIYDIMLNCWDEKQSSRASFTDLRK 808 ******************************************************************************9976 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.0 0.0 3.9e-22 7.7e-19 1 90 [] 28 117 .. 28 117 .. 0.95 2 ! 51.8 0.0 4.5e-17 8.8e-14 16 90 .] 162 235 .. 157 235 .. 0.94 3 ! 20.7 0.2 2.4e-07 0.00046 6 88 .. 249 352 .. 244 353 .. 0.84 Alignments for each domain: == domain 1 score: 68.0 bits; conditional E-value: 3.9e-22 I-set 1 pkftqkl.kdvevkeGesaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 p+f +k+ + +v++G +++l c+v+G+p p+ sW+kd+++l+ s+r+++ a++ + +I+n + D+G+Ytc a ns+g+++a++eL+V FUN_002102-T1 28 PRFGKKPkVQNNVQVGHNVRLRCSVKGDPLPRLSWVKDEKPLQFSSRIRLIARD-NGIVKIKNTQLVDAGNYTCIAANSLGTVNATLELHV 117 788899956779**************************************9999.8899******************************98 PP == domain 2 score: 51.8 bits; conditional E-value: 4.5e-17 I-set 16 esaeleckvsGepepevsWlkdgselkeskrvkvkaeegtatLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 +++l+c+++G+p+++++Wlkdg+ l + +r+ +++ L++++v ++D+GkYtc +tn +g+ +++ +L+V FUN_002102-T1 162 HTIRLKCEATGAPPLQFRWLKDGQRLLS-RRMDPYLNSSLWFLRLRDVVPDDSGKYTCIVTNPYGSINHTYTLNV 235 589************************5.8888888889*********************************998 PP == domain 3 score: 20.7 bits; conditional E-value: 2.4e-07 I-set 6 klkdvevkeGesaeleckvsGe.pepevsWlkdgselke..................skrvkvkaee..gtatLtIsnvkkeDeGkYtckatnsag 80 +++++vk G++ +++c v + p+++Wlk ++++++ ++k +++ + +I nv+ +D G Ytc ++n +g FUN_002102-T1 249 LPRNTTVKLGDNTTMKCIVLVSgTLPDFRWLKWDKNITSqpkmngtmkangsnklidPIHYKTIKDGeyHGVQVEIYNVSDNDFGLYTCFVSNHIG 344 5899*************975442389*************99999999999988887544555555555667799********************** PP I-set 81 eaeasaeL 88 + sa L FUN_002102-T1 345 YDYNSAFL 352 98887766 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.1 0.0 2.4e-17 4.8e-14 1 78 [] 27 104 .. 27 104 .. 0.88 2 ! 44.1 0.0 1.5e-14 3e-11 14 78 .] 159 222 .. 142 222 .. 0.80 3 ! 32.2 0.1 8.1e-11 1.6e-07 8 78 .] 250 341 .. 246 341 .. 0.89 4 ? -1.7 0.0 3.1 6.1e+03 45 63 .. 637 655 .. 628 658 .. 0.66 Alignments for each domain: == domain 1 score: 53.1 bits; conditional E-value: 2.4e-17 Ig_3 1 kPvitvspsstv.veegesvtLtCeaegnppptitWykngke.lssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 +P++ +p+ + v++g +v+L+C+++g+p p+ +W k++k+ + s++ + +n+ ++i+n++ d+G+YtC+A N FUN_002102-T1 27 PPRFGKKPKVQNnVQVGHNVRLRCSVKGDPLPRLSWVKDEKPlQFSSRIR--LIARDNGIVKIKNTQLVDAGNYTCIAAN 104 67777788888889***************************854443333..89************************99 PP == domain 2 score: 44.1 bits; conditional E-value: 1.5e-14 Ig_3 14 eegesvtLtCeaegnppptitWykngkelssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 +++L+Cea+g pp +++W+k+g++l s + + + +ss L++++v ++dsG+YtC+++N FUN_002102-T1 159 PASHTIRLKCEATGAPPLQFRWLKDGQRLLSRRMDP-YLNSSLWFLRLRDVVPDDSGKYTCIVTN 222 56789**********************977744442.45555555*******************9 PP == domain 3 score: 32.2 bits; conditional E-value: 8.1e-11 Ig_3 8 psstvveegesvtLtCea.egnppptitWykngkelssgstskr....................sssssnstLtisnvtredsGtYtCvAsN 78 p++t+v+ g++ t++C + ++ p+++W+k +k+++s+++ + + ++ +++i nv+ +d G YtC +sN FUN_002102-T1 250 PRNTTVKLGDNTTMKCIVlVSGTLPDFRWLKWDKNITSQPKMNGtmkangsnklidpihyktikDGEYHGVQVEIYNVSDNDFGLYTCFVSN 341 778889************9999999*********877755554489999***********999777777778*******************9 PP == domain 4 score: -1.7 bits; conditional E-value: 3.1 Ig_3 45 gstskrsssssnstLtisn 63 + ++ +ss+s++s+Lti++ FUN_002102-T1 637 EYQQAKSSGSGGSSLTIRD 655 233333889999****986 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.1 0.0 1.4e-40 2.7e-37 3 256 .. 539 806 .. 537 809 .. 0.85 Alignments for each domain: == domain 1 score: 129.1 bits; conditional E-value: 1.4e-40 Pkinase 3 vleklGeGsfgkVykav.....eketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdlls.. 90 + e+lGeG+fg V++a + t + vA+K++k + ++++ ++l+E++ +k++ h+ni++li++++++ l++v+E+++ g+l ++l+ FUN_002102-T1 539 IREQLGEGAFGLVMRADavglpDMPTTNSVAVKMLKADATENEL-ADLLSEMDTMKEIGkHKNIINLIGACTQNGPLFVVVEFAPFGNLRQFLRer 633 6799*********99862222256899*********99888765.69***********99**********************************66 PP Pkinase 91 ......rkgalsee.............eakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk...ltsfvgtseYm 164 + + + +++ qi++g+eyl +++vHrDl NiL+ e+ +Ki+DFGla+++++ + +t+ +++ FUN_002102-T1 634 rpseyqQ------AkssgsggssltirDFVSFAFQIARGMEYLGTKKCVHRDLAARNILVGEDYVMKIADFGLARNVRDLEYyrkTTDGRLPIKWL 723 5555550......144555555555559999*********************************************99988776677888889*** PP Pkinase 165 APEvlkskkygkkvDvWslGvilyellt.gkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeel 256 A E l ++ y++++DvW+ G++l+e++t g +p+++ ++ l+++l ++ +++p+++ +++ d++ +++++++++R ++++l FUN_002102-T1 724 AIEALFDRVYTTQSDVWAFGILLWEIFTlGGSPYPGIPIEK--------LFELL--KSGYRMQKPQNCPNDIYDIMLNCWDEKQSSRASFTDL 806 *************************976599****444433........22233..34578899*************************9987 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.5 0.0 1.2e-10 2.3e-07 5 79 .. 40 111 .. 37 113 .. 0.90 2 ! 29.9 0.0 3.7e-10 7.2e-07 8 76 .. 161 226 .. 158 230 .. 0.88 3 ! 28.5 0.1 9.9e-10 1.9e-06 2 75 .. 252 344 .. 251 348 .. 0.82 Alignments for each domain: == domain 1 score: 31.5 bits; conditional E-value: 1.2e-10 ig 5 vleGesatLtCsasegspgpdvtWskegktkieslkvkedngrttqssllisnvteedaGtYtCvvnnpggsatl 79 v++G++++L+Cs++ g+p p ++W k+ k ++ s++++ +++++ + i n+++ daG+YtC + n++g +++ FUN_002102-T1 40 VQVGHNVRLRCSVK-GDPLPRLSWVKDEKPLQFSSRIRLIARDNGI--VKIKNTQLVDAGNYTCIAANSLGTVNA 111 789***********.*********************6666666666..789******************998876 PP == domain 2 score: 29.9 bits; conditional E-value: 3.7e-10 ig 8 GesatLtCsasegspgpdvtWskegktkieslkvkedngrttqs.sllisnvteedaGtYtCvvnnpggs 76 +++++L C+a+ g p+ ++ W k+g+++ + + d + +++ l +++v ++d+G YtC v+np gs FUN_002102-T1 161 SHTIRLKCEAT-GAPPLQFRWLKDGQRLLSRRM---DPYLNSSLwFLRLRDVVPDDSGKYTCIVTNPYGS 226 7899*******.******************999...666666665677999***************9887 PP == domain 3 score: 28.5 bits; conditional E-value: 9.9e-10 ig 2 tvtvleGesatLtCsasegspgpdvtWskegktkieslk..........vkedngrttqs..................sllisnvteedaGtYtCv 69 ++tv+ G++ t+ C + + + pd+ W k +k ++++ k ++ i nv+ +d G YtC FUN_002102-T1 252 NTTVKLGDNTTMKCIVLVSGTLPDFRWLKWDKNITSQPKmngtmkangsN---------KlidpihyktikdgeyhgvQVEIYNVSDNDFGLYTCF 338 799**************9*********************65555555550.........1555555555555666667****************** PP ig 70 vnnpgg 75 v+n+ g FUN_002102-T1 339 VSNHIG 344 ***987 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.7 0.0 7.3e-14 1.4e-10 9 79 .] 38 117 .. 32 117 .. 0.84 2 ! 35.6 0.0 5.9e-12 1.2e-08 12 69 .. 159 226 .. 148 236 .. 0.78 3 ! 11.4 0.4 0.00021 0.42 8 74 .. 251 349 .. 242 354 .. 0.66 Alignments for each domain: == domain 1 score: 41.7 bits; conditional E-value: 7.3e-14 Ig_2 9 tvvtegesvtLtCsasgnppakytwykdgkvls.ssqn.........fftsnvsaedsGtYtCtarntkggkvsnpveitv 79 +v g++v+L+Cs++g+p + ++w kd+k+l+ ss+ + ++n ++ d+G+YtC a n + g+v++++e++v FUN_002102-T1 38 NNVQVGHNVRLRCSVKGDPLPRLSWVKDEKPLQfSSRIrliardngiVKIKNTQLVDAGNYTCIAAN-SLGTVNATLELHV 117 5699*****************************7333355555556555699***************.88*******9987 PP == domain 2 score: 35.6 bits; conditional E-value: 5.9e-12 Ig_2 12 tegesvtLtCsasgnppakytwykdgkvlsssqn.........fft.snvsaedsGtYtCtarntkgg 69 + +++++L+C+a g+pp +++w kdg+ l s++ f++ + v ++dsG YtC ++n+ g+ FUN_002102-T1 159 PASHTIRLKCEATGAPPLQFRWLKDGQRLLSRRMdpylnsslwFLRlRDVVPDDSGKYTCIVTNPYGS 226 567899********************88885444466667776665566***************8864 PP == domain 3 score: 11.4 bits; conditional E-value: 0.00021 Ig_2 8 p.tvvtegesvtLtCsas.gnppakytwykdgkvlsssqn...............................fftsnvsaedsGtYtCtarntkggk 70 t+v g++ t++C + + ++++w k +k + s+++ + + nvs +d G YtC ++n ++g FUN_002102-T1 251 RnTTVKLGDNTTMKCIVLvSGTLPDFRWLKWDKNITSQPKmngtmkangsnklidpihyktikdgeyhgvqVEIYNVSDNDFGLYTCFVSN-HIGY 345 3588999*********8854447**999999966664444445555556666666644444444443333333577999999********9.7776 PP Ig_2 71 vsnp 74 ++n+ FUN_002102-T1 346 DYNS 349 6665 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.1 5.8e-06 0.011 7 108 .. 39 117 .. 33 118 .. 0.80 2 ? 0.4 0.0 0.53 1e+03 8 37 .. 158 184 .. 152 190 .. 0.84 3 ! 13.7 0.1 3.8e-05 0.074 74 108 .. 202 235 .. 191 236 .. 0.90 4 ! 26.2 0.0 5.1e-09 1e-05 3 95 .. 250 343 .. 248 352 .. 0.86 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 5.8e-06 V-set 7 tvaeGesvtLtCslssseseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCavipkgevvfgk 102 +v++G++v+L+Cs++ + +++W ++++ +++ + r++l r ++ ++i+n +l D+G YtC +++ + ++ FUN_002102-T1 39 NVQVGHNVRLRCSVKGD---PLPRLSWVKDEKP-------LQF---------SSRIRLIA---RDNGIVKIKNTQLVDAGNYTCI-AANSLGTVNA 111 68889999999988888...8999999997754.......444.........44666666...88*******************9.7888888888 PP V-set 103 gtrLtV 108 +++L+V FUN_002102-T1 112 TLELHV 117 888877 PP == domain 2 score: 0.4 bits; conditional E-value: 0.53 V-set 8 vaeGesvtLtCslssseseasqsvyWyrqp 37 ++ ++++L+C+ + + +++W ++ FUN_002102-T1 158 WPASHTIRLKCEATGA---PPLQFRWLKDG 184 566799*****99998...9******9975 PP == domain 3 score: 13.7 bits; conditional E-value: 3.8e-05 V-set 74 sltiqnltlsDsGtYtCavipkgevvfgkgtrLtV 108 l+++++ ++DsG YtC +++++++ +++++L+V FUN_002102-T1 202 FLRLRDVVPDDSGKYTCI-VTNPYGSINHTYTLNV 235 699***************.8***********9999 PP == domain 4 score: 26.2 bits; conditional E-value: 5.1e-09 V-set 3 prevtvaeGesvtLtCslsss.eseasqsvyWyrqppgkepteliayysnkseeekkkgrfslrkdpsrsdfsltiqnltlsDsGtYtCav.ipk 95 pr +tv +G + t++C + s + + +++W + ++ +p+ ++ n+s++ +++ +++ kd +++ ++++i n++ +D G+YtC v ++ FUN_002102-T1 250 PRNTTVKLGDNTTMKCIVLVSgTLPDFRWLKWDKNITS-QPKMNGTMKANGSNKLIDPIHYKTIKDGEYHGVQVEIYNVSDNDFGLYTCFVsNHI 343 899*************8886756667777777777776.**************************************************975333 PP >> C2-set_2 CD80-like C2-set immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 1.2e-05 0.024 8 44 .. 36 72 .. 31 122 .. 0.79 2 ? 5.7 0.0 0.011 22 15 41 .. 162 187 .. 150 223 .. 0.81 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.2e-05 C2-set_2 8 slleae.ekevvatCvsaggkPapritWlldgkeleaa 44 ++ +++ + +v ++C s +g P pr++W +d+k+l+ + FUN_002102-T1 36 VQNNVQvGHNVRLRC-SVKGDPLPRLSWVKDEKPLQFS 72 4444457899*****.67899*************9333 PP == domain 2 score: 5.7 bits; conditional E-value: 0.011 C2-set_2 15 kevvatCvsaggkPapritWlldgkel 41 + ++C a g P+ + +Wl+dg+ l FUN_002102-T1 162 HTIRLKC-EATGAPPLQFRWLKDGQRL 187 5667889.7788889**********99 PP >> C2-set_3 Butyrophilin subfamily 3 member A2-like, Ig-C domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 5e-06 0.0097 2 81 .. 31 106 .. 30 110 .. 0.85 2 ? 3.0 0.0 0.071 1.4e+02 14 80 .. 161 223 .. 157 228 .. 0.69 3 ? -3.4 0.0 7.2 1.4e+04 63 80 .. 325 342 .. 310 343 .. 0.76 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 5e-06 C2-set_3 2 GsdpqisvegyedggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnpl 81 G +p+++ +++ ++rl C+++G P P+ +W + ++ s+ l ++++g+ +++++ +v + +n++C+ n+l FUN_002102-T1 31 GKKPKVQNNVQVGHNVRLRCSVKGD-PLPRLSWVKDEKPLQFSSRIRLIARDNGIVKIKNTQLVDA---GNYTCIAANSL 106 899********************95.*******8877744444555577788***********975...899***99986 PP == domain 2 score: 3.0 bits; conditional E-value: 0.071 C2-set_3 14 dggirlvCrsaGWyPePqvqWrdekgeklpslseklsqdedglfevetslvvressnknvsCsirnp 80 + irl+C+++G P q W + + l+ + + + l+ ++ vv ++s ++++C+++np FUN_002102-T1 161 SHTIRLKCEATGA-PPLQFRWLKDGQRLLSRRMDPYLN--SSLWFLRLRDVVPDDS-GKYTCIVTNP 223 56899****9996.777999987655444444444443..3577777777777765.6789999997 PP == domain 3 score: -3.4 bits; conditional E-value: 7.2 C2-set_3 63 lvvressnknvsCsirnp 80 + v+++ + ++C+++n+ FUN_002102-T1 325 YNVSDNDFGLYTCFVSNH 342 456777788899999996 PP >> V-set_CD47 CD47 immunoglobulin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.2 0.0 0.0015 2.9 70 101 .. 85 117 .. 40 122 .. 0.79 2 ! 6.2 0.0 0.0061 12 78 103 .. 212 237 .. 161 241 .. 0.75 3 ? 2.0 0.1 0.12 2.4e+02 69 88 .. 296 341 .. 262 347 .. 0.68 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0015 V-set_CD47 70 Lkldfsdal.sGnYtCevtelsnevkttieLkl 101 +k+++ + + +GnYtC + + v+ t+eL++ FUN_002102-T1 85 VKIKNTQLVdAGNYTCIAANSLGTVNATLELHV 117 66777766668*********9999999999975 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0061 V-set_CD47 78 lsGnYtCevtelsnevkttieLklvv 103 sG YtC vt+ ++++t L++v FUN_002102-T1 212 DSGKYTCIVTNPYGSINHTYTLNVVA 237 48*****************9999865 PP == domain 3 score: 2.0 bits; conditional E-value: 0.12 V-set_CD47 69 t..........................LkldfsdalsGnYtCevte 88 + + + sd+ G YtC v++ FUN_002102-T1 296 KangsnklidpihyktikdgeyhgvqvEIYNVSDNDFGLYTCFVSN 341 4445555556666666666666666544578999********9976 PP >> Ig_5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.00065 1.3 6 72 .. 42 118 .. 38 121 .. 0.75 2 ? 3.4 0.0 0.075 1.5e+02 9 60 .. 163 223 .. 160 238 .. 0.57 3 ? -0.4 0.1 1.2 2.3e+03 34 59 .. 317 341 .. 258 352 .. 0.74 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00065 Ig_5 6 sgttVtltCpeese..eeikWekndkelkdkeekeLvlen.......FsevedsGyysCykesskk.akhyLylkar 72 g +V l+C+ + + +++W k++k l+ ++ +L+ + ++ d G y+C + +s +++L l++r FUN_002102-T1 42 VGHNVRLRCSVKGDplPRLSWVKDEKPLQFSSRIRLIARDngivkikNTQLVDAGNYTCIAANSLGtVNATLELHVR 118 599*******99998899********9998777777654311111113667789******99996558888888776 PP == domain 2 score: 3.4 bits; conditional E-value: 0.075 Ig_5 9 tVtltCpeese..eeikWekndkelkd.....keekeLvlenFsev..edsGyysCykess 60 t+ l+C + +++W k++++l + +++L +v +dsG+y+C ++ FUN_002102-T1 163 TIRLKCEATGAppLQFRWLKDGQRLLSrrmdpYLNSSLWFLRLRDVvpDDSGKYTCIVTNP 223 56677766555445677777766554421112334455555555555589******98874 PP == domain 3 score: -0.4 bits; conditional E-value: 1.2 Ig_5 34 keekeLvlenFsevedsGyysCykes 59 ++ ++++ n s+ +d G y+C ++ FUN_002102-T1 317 YHGVQVEIYNVSD-NDFGLYTCFVSN 341 3455666667777.677888887665 PP >> Ig_C17orf99 C17orf99 Ig domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.047 92 64 90 .. 90 116 .. 35 119 .. 0.79 2 ? 3.8 0.0 0.044 86 12 89 .. 157 233 .. 151 238 .. 0.73 3 ? 3.4 0.0 0.056 1.1e+02 49 94 .. 312 357 .. 305 358 .. 0.83 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.047 Ig_C17orf99 64 kssPdlltyaCqAantsgvqasslvLq 90 + d +y+C Aan++g+ + +l L+ FUN_002102-T1 90 TQLVDAGNYTCIAANSLGTVNATLELH 116 44557779**********998887775 PP == domain 2 score: 3.8 bits; conditional E-value: 0.044 Ig_C17orf99 12 vfpksrrvlisChasegspPItYsLvgkkgivvakkivkegkPAnFsllitlkssPd.lltyaCqAantsgvqasslvL 89 p s+++ + C+a+ g+pP+ ++ + k+g+ ++ ++++++ + +l Pd +y+C n g +++ +L FUN_002102-T1 157 AWPASHTIRLKCEAT-GAPPLQFRWL-KDGQRLLSRRMDPYLNSSLWFLRLRDVVPDdSGKYTCIVTNPYGSINHTYTL 233 678999*******96.7899***988.5778888888888877777766666655541567888777777766666665 PP == domain 3 score: 3.4 bits; conditional E-value: 0.056 Ig_C17orf99 49 vkegkPAnFsllitlkssPdlltyaCqAantsgvqasslvLqlyae 94 +k+g+ +++i + s+ d+ y+C +n +g + +s+ L + e FUN_002102-T1 312 IKDGEYHGVQVEIYNVSDNDFGLYTCFVSNHIGYDYNSAFLIKFEE 357 55555556677888999**********************9998876 PP >> Haspin_kinase Haspin like kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.027 54 144 177 .. 254 291 .. 232 300 .. 0.80 2 ? 6.0 0.0 0.0038 7.4 229 255 .. 677 703 .. 654 715 .. 0.87 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.027 Haspin_kinase 144 elsl...kelkllklvkGt.pglllllwdkllrsepdf 177 +++l + +k + lv Gt p++ +l wdk + s+p + FUN_002102-T1 254 TVKLgdnTTMKCIVLVSGTlPDFRWLKWDKNITSQPKM 291 455555577899******************99998754 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0038 Haspin_kinase 229 HRdLhldniLvdknlnvtlidyklaRa 255 HRdL niLv + + + d+ laR FUN_002102-T1 677 HRDLAARNILVGEDYVMKIADFGLARN 703 *************************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (857 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1159 (0.0453709); expected 510.9 (0.02) Passed bias filter: 1056 (0.0413388); expected 510.9 (0.02) Passed Vit filter: 93 (0.00364063); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.45u 0.43s 00:00:00.88 Elapsed: 00:00:00.44 # Mc/sec: 7919.07 // Query: FUN_002103-T1 [L=640] Description: FUN_002103 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-96 321.9 0.0 4.9e-96 321.5 0.0 1.1 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 6.6e-42 144.2 0.0 1e-41 143.6 0.0 1.2 1 Pkinase Protein kinase domain 1e-05 26.0 0.2 0.00015 22.2 0.0 2.7 2 I-set Immunoglobulin I-set domain 0.00027 21.6 0.1 0.0008 20.1 0.1 1.8 1 Ig_2 Immunoglobulin domain 0.0029 18.5 0.2 0.011 16.7 0.2 2.1 1 Ig_3 Immunoglobulin domain 0.0067 17.1 0.0 0.025 15.2 0.0 2.0 2 V-set Immunoglobulin V-set domain ------ inclusion threshold ------ 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 Kinase-like Kinase-like 0.052 13.8 3.0 0.095 12.9 3.0 1.4 1 TM_ErbB1 Epidermal growth factor receptor transmembran 0.091 12.0 0.0 0.17 11.1 0.0 1.3 1 Pkinase_fungal Fungal protein kinase 0.096 12.2 0.1 0.17 11.4 0.1 1.5 1 Haspin_kinase Haspin like kinase domain 0.24 11.6 0.1 0.52 10.5 0.1 1.5 1 DUF8063 Family of unknown function (DUF8063) 0.29 12.0 1.9 1.3 9.9 0.1 2.7 3 ig Immunoglobulin domain 6 7.6 5.5 3.3 8.4 0.6 2.6 2 DUF7248 Family of unknown function (DUF7248) Domain annotation for each model (and alignments): >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 321.5 0.0 2.5e-99 4.9e-96 3 258 .] 323 592 .. 321 592 .. 0.98 Alignments for each domain: == domain 1 score: 321.5 bits; conditional E-value: 2.5e-99 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlke..ekekkkikVavKtlkeeaseeekeefleeaklmkkl.shpnivkllgvcteeepllivteyvegGsLkefLrk 94 +ke GeGafG V k+++ + +k ++ + VavK+lke+as+ e ++f++e+++mk++ sh+niv++lg+ct ++pl++++ey+++G+Lk+fLr+ FUN_002103-T1 323 IKELAGEGAFGYVAKAKAFQlpNKVSTPCIVAVKMLKENASDVELADFISEMEMMKEIgSHKNIVNYLGACTVHGPLFLIVEYCSHGNLKDFLRN 417 67778**************98888889999***************************************************************** PP PK_Tyr_Ser-Thr 95 k...........keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslke 178 + + +l+ ++ll++a+qi kGm+yL+skk++HrdlaarNvL++e+ v+ki+DfGL+r++ ++dyy+++++++lp+kW+a+E+l + FUN_002103-T1 418 NrpsllelsgdmEVSLTFRDLLSFAYQITKGMSYLSSKKCIHRDLAARNVLIAEDFVIKIADFGLSRNLGNTDYYRRTTHGRLPVKWLAIEALFD 512 ************9********************************************************************************** PP PK_Tyr_Ser-Thr 179 kkftsksDvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfkelveel 258 +++t k+DvWsfG+llwEiftlg +py+g+ e++++ll++g+r+e+p ncp+e+ye+m++Cw+ d+++Rp+f+el +l FUN_002103-T1 513 QQYTMKTDVWSFGILLWEIFTLGGSPYPGIPVEQLFSLLKTGYRMECPINCPTEMYEIMMQCWSDDARNRPSFDELYGKL 592 ***************************************************************************98765 PP >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 143.6 0.0 5.1e-45 1e-41 4 256 .. 324 588 .. 321 592 .. 0.88 Alignments for each domain: == domain 1 score: 143.6 bits; conditional E-value: 5.1e-45 Pkinase 4 leklGeGsfgkVykav......eketgkivAiKkikkekakkkkekkvlrEikilkklk.hpnivrlidvfeekdelylvlEyveggelfdlls.. 90 +e GeG+fg V ka+ + +t +ivA+K++k++ + + ++++E++++k++ h+niv+++++++ + l+l++Ey+++g+l+d+l+ FUN_002103-T1 324 KELAGEGAFGYVAKAKafqlpnKVSTPCIVAVKMLKENASDV-ELADFISEMEMMKEIGsHKNIVNYLGACTVHGPLFLIVEYCSHGNLKDFLRnn 418 6677********9997444443568999******98876655.5579***********99**********************************88 PP Pkinase 91 ..........rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk...ltsfvgtseYmAPEvlkskk 173 + +l+ +++ ++++qi +g++yl s++++HrDl N+Li e+ +Ki+DFGl+++l ++ +t+ +++A E l +++ FUN_002103-T1 419 rpsllelsgdMEVSLTFRDLLSFAYQITKGMSYLSSKKCIHRDLAARNVLIAEDFVIKIADFGLSRNLGNTDYyrrTTHGRLPVKWLAIEALFDQQ 514 888888887666778888**********************************9999**************98887788888899************ PP Pkinase 174 ygkkvDvWslGvilyellt.gkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeel 256 y+ k+DvWs G++l+e++t g +p+++ ++ql+++lk + ++ p ++ e+ +++ ++++ d ++R++++el FUN_002103-T1 515 YTMKTDVWSFGILLWEIFTlGGSPYPGIP--------VEQLFSLLK--TGYRMECPINCPTEMYEIMMQCWSDDARNRPSFDEL 588 ****************976599****443........445444444..4567889999**********************9997 PP >> I-set Immunoglobulin I-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.0 7.6e-08 0.00015 56 90 .] 137 171 .. 55 171 .. 0.93 2 ? -0.5 0.0 0.91 1.8e+03 32 64 .. 236 267 .. 233 286 .. 0.72 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 7.6e-08 I-set 56 atLtIsnvkkeDeGkYtckatnsageaeasaeLtV 90 + L+I+n++ +D+G Y+c++ n+ g++ +sa LtV FUN_002103-T1 137 SYLVIHNATVHDSGLYSCVVCNQHGRDFSSAFLTV 171 679******************************98 PP == domain 2 score: -0.5 bits; conditional E-value: 0.91 I-set 32 vsWlkd..gselkeskrvkvkaeegtatLtIsnvk 64 +W+k +++++e ++++ +++t +Lt + v FUN_002103-T1 236 LTWKKPinDENISE---HSIQVKQQTVELTGETVA 267 58999876777774...666666666777766555 PP >> Ig_2 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.1 4.1e-07 0.0008 18 78 .. 101 172 .. 95 173 .. 0.64 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 4.1e-07 Ig_2 18 tLtCsasgnppakytwykdgkvls...ssqn........fftsnvsaedsGtYtCtarntkggkvsnpv.eit 78 +L Cs + + + ++t +++ +s s ++ ++++n++++dsG Y+C+++n++g s+ + ++t FUN_002103-T1 101 SLYCSLDLD-NGNFTVIDENSKFSikpSAPDdignhwsyLVIHNATVHDSGLYSCVVCNQHGRDFSSAFlTVT 172 555666643.44455555554444343333355557764455*******************977766664766 PP >> Ig_3 Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.2 5.7e-06 0.011 16 78 .] 97 158 .. 54 158 .. 0.80 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 5.7e-06 Ig_3 16 gesvtLtCeaegnppptitWykngke...lssgstskrsssssnstLtisnvtredsGtYtCvAsN 78 ++++L C+ + ++t ++++ ++s ++ +++ s L i+n+t +dsG Y+Cv+ N FUN_002103-T1 97 SNDISLYCSL-DLDNGNFTVIDENSKfsiKPSAPD---DIGNHWSYLVIHNATVHDSGLYSCVVCN 158 5678888888.333336666666666543333222...689999*******************966 PP >> V-set Immunoglobulin V-set domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 1.3e-05 0.025 63 100 .. 127 164 .. 69 172 .. 0.71 2 ? -3.0 0.0 6.1 1.2e+04 41 80 .. 397 438 .. 394 438 .. 0.78 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.3e-05 V-set 63 slrkdpsrsdfsltiqnltlsDsGtYtCav.ipkgevvf 100 s+ +d+ ++ l i+n+t+ DsG+Y C+v + + +f FUN_002103-T1 127 SAPDDIGNHWSYLVIHNATVHDSGLYSCVVcN-QHGRDF 164 455578888889*****************843.333333 PP == domain 2 score: -3.0 bits; conditional E-value: 6.1 V-set 41 epteliayysn..kseeekkkgrfslrkdpsrsdfsltiqnl 80 +p +li+ y + + + + + +r sl + +slt+++l FUN_002103-T1 397 GPLFLIVEYCShgNLKDFLRNNRPSLLELSGDMEVSLTFRDL 438 577888899887777778888999999988888888888875 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 2.1e-05 0.042 153 247 .. 444 534 .. 428 552 .. 0.88 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.1e-05 Kinase-like 153 qlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvragtkvv.sevekgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIysiwcl 247 q+ + +L sk +h ++ ++n+l+ e + +++ +f+ g+ +++g P l+ ++ + + + t+k+d+W G+ ++ i l FUN_002103-T1 444 QITKGMSYLSSKKCIHRDLAARNVLIAEDFVIKIADFGLSRNLGNTDYyRRTTHGRLPVKWLAIEAL-FDQ----QYTMKTDVWSFGILLWEIFTL 534 66666789*****************************9877777655559999**********9777.888....99***********99998765 PP >> TM_ErbB1 Epidermal growth factor receptor transmembrane-juxtamembrane segment # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 3.0 4.8e-05 0.095 1 27 [. 201 226 .. 201 229 .. 0.86 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 4.8e-05 TM_ErbB1 1 iaaGVVGGlLllvilaLvifvllRRRr 27 i+ G +GG+ ++ il+ + f+ ++RRr FUN_002103-T1 201 IILGSIGGIIAV-ILVAIAFLVWKRRR 226 78899****999.99999999999998 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 8.6e-05 0.17 296 379 .. 446 524 .. 433 531 .. 0.76 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 8.6e-05 Pkinase_fungal 296 ikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielsessasgarertGTl..eFmaiellkgeeHtyrhDLESf 379 k+ L ++ +HrD ++ N++i +d + D+ l+ +l+ +++ +r+ G l +++aie l +++ t+ D+ Sf FUN_002103-T1 446 TKGMSYLS-SKKCIHRDLAARNVLIA-----EDFVIKIADFGLSRNLG-NTDYYRRTTHGRLpvKWLAIEALFDQQYTMKTDVWSF 524 45566666.99***************.....57899999999999999.4555566667765116899**9999999999999987 PP >> Haspin_kinase Haspin like kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 8.5e-05 0.17 204 256 .. 435 486 .. 226 499 .. 0.82 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 8.5e-05 Haspin_kinase 204 waqalsifwqivkilyvaEtkfqFEHRdLhldniLvdknlnvtlidyklaRak 256 +++ ls +qi+k ++ k + HRdL n+L+ + + + d+ l+R FUN_002103-T1 435 FRDLLSFAYQITKGMSYLSSK-KCIHRDLAARNVLIAEDFVIKIADFGLSRNL 486 456677778888888766555.457**************************64 PP >> DUF8063 Family of unknown function (DUF8063) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.1 0.00026 0.52 111 169 .. 169 228 .. 162 232 .. 0.76 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00026 DUF8063 111 VsitTeqs.egyavivstqgseiggP.feafggaqaag.laGalmavllallaalyvvrren 169 +++tT+ + + s+++s+ +P f + + g ++G+++++l+a+++ ++++rr FUN_002103-T1 169 LTVTTPSTpARAFTGSSSPSSSHHSPsFLSA--KIILGsIGGIIAVILVAIAFLVWKRRRSK 228 7899998876666667776777777878887..457777*************8888777754 PP >> ig Immunoglobulin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 1.5 2.9e+03 5 30 .. 67 95 .. 63 101 .. 0.83 2 ? 9.9 0.1 0.00066 1.3 52 75 .. 138 161 .. 102 166 .. 0.84 3 ? -0.9 0.1 1.5 2.9e+03 20 53 .. 230 266 .. 226 294 .. 0.76 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.5 ig 5 vleGesatLtCsas...egspgpdvtWsk 30 + + + at++C+ + g g ++ W+k FUN_002103-T1 67 ITQNNLATFSCKQEilgAGLAGLQFDWIK 95 6678899****999988888888999876 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00066 ig 52 sllisnvteedaGtYtCvvnnpgg 75 l i n+t d+G Y+Cvv n +g FUN_002103-T1 138 YLVIHNATVHDSGLYSCVVCNQHG 161 58999**************99887 PP == domain 3 score: -0.9 bits; conditional E-value: 1.5 ig 20 gspgpdvtWskegktkieslk...vkedngrttqssl 53 +s ++tW+k + ++ s++ vk+++ t++++ FUN_002103-T1 230 QSLLMILTWKKPINDENISEHsiqVKQQTVELTGETV 266 6666778999998888888887666666555555554 PP >> DUF7248 Family of unknown function (DUF7248) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.4 0.59 1.2e+03 12 29 .. 6 23 .. 3 24 .. 0.78 2 ? 8.4 0.6 0.0017 3.3 7 33 .. 195 222 .. 189 224 .. 0.85 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.59 DUF7248 12 iivwvfiivlivilamia 29 i+ +i++ ++il +ia FUN_002103-T1 6 IVQSAWIFMNVFILKVIA 23 778889999999988775 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0017 DUF7248 7 nwir.kiivwvfiivlivilamialvgy 33 ++++ kii+ ++ +++vil+ ia+ ++ FUN_002103-T1 195 SFLSaKIILGSIGGIIAVILVAIAFLVW 222 55667********************998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (640 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1119 (0.043805); expected 510.9 (0.02) Passed bias filter: 970 (0.0379722); expected 510.9 (0.02) Passed Vit filter: 102 (0.00399295); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 13 [number of targets reported over threshold] # CPU time: 0.41u 0.39s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 6167.27 // Query: FUN_002104-T1 [L=207] Description: FUN_002104 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.23 12.0 0.5 0.36 11.4 0.5 1.3 1 DUF8026 Family of unknown function (DUF8026) 0.24 11.8 0.4 0.86 10.0 0.1 1.8 2 ApoO Apolipoprotein O Domain annotation for each model (and alignments): >> DUF8026 Family of unknown function (DUF8026) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.5 2.8e-05 0.36 30 86 .. 47 102 .. 44 120 .. 0.86 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 2.8e-05 DUF8026 30 lRqeerklelleeqdridtysPraladlreWieanPddplaeearerynecveslre 86 lRq e+k+ lle+++ + + +al+ lr +++ P+ + +ea e +++ v+ r+ FUN_002104-T1 47 LRQLEEKVRLLEQEKAVAS-CDNALTALRRHLNRPPSLFDRHEAIELLESLVRLART 102 9**********99888876.679*********************9999998876554 PP >> ApoO Apolipoprotein O # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 0.11 1.5e+03 10 37 .. 41 69 .. 31 80 .. 0.66 2 ? 10.0 0.1 6.7e-05 0.86 10 49 .. 87 126 .. 74 132 .. 0.85 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.11 ApoO 10 etptdrLeeqvrkaRlflesklsa.vede 37 ++p +rL + +k+Rl ++k+ a ++++ FUN_002104-T1 41 PEPDERLRQLEEKVRLLEQEKAVAsCDNA 69 67888888888888887776654414444 PP == domain 2 score: 10.0 bits; conditional E-value: 6.7e-05 ApoO 10 etptdrLeeqvrkaRlflesklsavedelnkvkskvenae 49 + + Le+ vr aR ++++k++ ++++l++vk++ ++e FUN_002104-T1 87 HEAIELLESLVRLARTQAHDKAEEYSAALDEVKARQASLE 126 567789***************************9877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (207 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1336 (0.0522999); expected 510.9 (0.02) Passed bias filter: 871 (0.0340967); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.42s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 2087.44 // Query: FUN_002105-T1 [L=592] Description: FUN_002105 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-163 544.2 0.1 4.4e-163 544.0 0.1 1.0 1 5_nucleotid 5' nucleotidase family ------ inclusion threshold ------ 0.036 14.8 0.3 2.2 9.0 0.0 2.6 2 GST_C_3 Glutathione S-transferase, C-terminal domain 0.05 14.5 0.1 2.2 9.1 0.0 2.5 2 Hydrolase haloacid dehalogenase-like hydrolase 0.11 13.4 0.0 0.71 10.7 0.0 2.3 2 HAD haloacid dehalogenase-like hydrolase 0.19 12.2 0.0 0.37 11.3 0.0 1.4 1 NleF_casp_inhib NleF caspase inhibitor Domain annotation for each model (and alignments): >> 5_nucleotid 5' nucleotidase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 544.0 0.1 8.6e-167 4.4e-163 1 459 [. 57 509 .. 57 510 .. 0.97 Alignments for each domain: == domain 1 score: 544.0 bits; conditional E-value: 8.6e-167 5_nucleotid 1 vFvnrelnlkkikvvGFDmDYTLaqYkseeleelaydlavekLveelgYPeeileleydpefairGLvlDkekGnllkvdrfknikvayhGlkels 96 +Fvnr+l+l+kik++GFDmDYTLa+Yks+ +e+ a+dl++ +L + +gYP+++l+++yd f++rGL++D e Gnllkvd+++ni v++hG+++l+ FUN_002105-T1 57 IFVNRSLSLDKIKFFGFDMDYTLAVYKSPVYEKKAFDLICGRLAS-IGYPQDVLKFQYDEAFPVRGLFFDCELGNLLKVDTYGNILVCVHGFEFLN 151 8******************************************66.************************************************** PP 5_nucleotid 97 keevkelYgnkliklseaskrlallntlFslpeavLlaqlvdlldkkeekak...g.....elelsyeslykdvreavdlvHrdgslkkevledle 184 +e+++lY+nk+++ ++ r+++lntlF+lpe+ L+a+lvd++d++++ ++ g el l+y+s+++dvr avd+vH +g+lk+ +l++le FUN_002105-T1 152 GHEIRSLYPNKFVQADSS--RYYILNTLFNLPETNLMACLVDYFDRSSDFKRtrnGvlssdELLLTYKSIHQDVRGAVDWVHDKGTLKQLTLDNLE 245 ***************996..9*************************97777776615667799********************************* PP 5_nucleotid 185 kYiekdpelvelLkrlreagkklfllTNSeydytnkvmkyllde...keekkkeWrdlFdvvivqarKPkFfeeerplrevdtetgklklkkvkge 277 Y++k+p+l +lL+r+r++g+k+f+lTNS y+yt+k++++llde +++k+W+++Fd+v v+arKP Ff e+++lr+vdtetg+l++++++ge FUN_002105-T1 246 TYVVKEPKLLQLLSRMRKNGRKTFILTNSGYSYTDKILSHLLDEkdeVGNTTKKWTTYFDYVGVNARKPLFFGEGTALRRVDTETGTLRIGRYSGE 341 *******************************************9887678899******************************************* PP 5_nucleotid 278 lekgkvYqgGslkelekllglkGkevLYvGDhiygDilkskkklgWrtalvvpeLeeElevlnekkekkeleelqkleelledelkelelsleaee 373 l++g++++gGs + +++llg++Gk++LY+GDhi+gDilkskkk+gWrt lv+peL++El+v+++++ + +++l++l+ l++ +k+l++ + FUN_002105-T1 342 LKEGQIFSGGSSDVFCNLLGAEGKDILYIGDHIFGDILKSKKKQGWRTYLVIPELTQELAVWQSRQ--DVFSKLHDLDAALAEIYKNLDSGT---- 431 *****************************************************************9..99****************999992.... PP 5_nucleotid 374 eskeeleelekeleelkeeikelreelkelfnkkfGslfrtgseeslFarqveryAdlYtskvsnLleysleklfrasrdllpHes 459 + + +++elk++i+++++++++++ ++Gslfr+g+++++Fa+q +ryAdlY++++ nLl+y++++lfra+ +l+pHes FUN_002105-T1 432 --T-----DKPDITELKNSIRDVTNTMETCY-GQMGSLFRSGNRQTFFASQATRYADLYAASCVNLLHYPFSYLFRAPPQLMPHES 509 ..2.....24699******************.9****************************************************7 PP >> GST_C_3 Glutathione S-transferase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.1 0.032 1.6e+02 32 69 .. 252 290 .. 236 308 .. 0.81 2 ? 9.0 0.0 0.00043 2.2 27 76 .. 447 496 .. 414 516 .. 0.76 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.032 GST_C_3 32 pkflkyfekvlkkngggylvg.dklTyADlalfqvldgl 69 pk l+ ++++ k++ +++++ + +y D +l ++ld FUN_002105-T1 252 PKLLQLLSRMRKNGRKTFILTnSGYSYTDKILSHLLDEK 290 9999999999999999999883569*****999999954 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00043 GST_C_3 27 keerlpkflkyfekvl.kkngggylvgdklTyADlalfqvldgleepkakd 76 ++++++ +++++ ++ + n +++++ + + yADl+ ++++ l++p++ FUN_002105-T1 447 VTNTMETCYGQMGSLFrSGNRQTFFASQATRYADLYAASCVNLLHYPFS-Y 496 56788888888888888899999*******************9999543.3 PP >> Hydrolase haloacid dehalogenase-like hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.00043 2.2 101 136 .. 252 288 .. 194 312 .. 0.81 2 ? 2.6 0.0 0.043 2.2e+02 164 184 .. 357 378 .. 354 379 .. 0.88 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00043 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx RF Hydrolase 101 pgaaealkaLkerGiklailtgdnretaeallre.lG 136 p++ ++l++ +++G k++ilt++ ++ +++l + l+ FUN_002105-T1 252 PKLLQLLSRMRKNGRKTFILTNSGYSYTDKILSHlLD 288 57779************************99999777 PP == domain 2 score: 2.6 bits; conditional E-value: 0.043 xxxxxxxxxxxxxxxxxxx.xx RF Hydrolase 164 lerlgvkpeevlmvGDgln.Di 184 ++ lg++++++l++GD + Di FUN_002105-T1 357 CNLLGAEGKDILYIGDHIFgDI 378 789*************998776 PP >> HAD haloacid dehalogenase-like hydrolase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.58 3e+03 2 12 .. 72 82 .. 71 92 .. 0.82 2 ? 10.7 0.0 0.00014 0.71 87 130 .. 251 296 .. 202 327 .. 0.80 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.58 HAD 2 lfDlDgTLldg 12 fD+D TL+ FUN_002105-T1 72 GFDMDYTLAVY 82 6*******865 PP == domain 2 score: 10.7 bits; conditional E-value: 0.00014 HAD 87 hpgalellaahraaGdrvvvvsgslrpllepll.aalg.fdevlat 130 p l+ll + r++G ++ ++++s ++ ++l + l+ dev +t FUN_002105-T1 251 EPKLLQLLSRMRKNGRKTFILTNSGYSYTDKILsHLLDeKDEVGNT 296 4799*****************************6677766666444 PP >> NleF_casp_inhib NleF caspase inhibitor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 7.3e-05 0.37 11 55 .. 411 455 .. 404 465 .. 0.87 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 7.3e-05 NleF_casp_inhib 11 ktlkdIksklkvifereisstTaekkikElsdkltklknsvlser 55 l+d+++ l +i+++ s tT + i El++ + ++ n +++ FUN_002105-T1 411 SKLHDLDAALAEIYKNLDSGTTDKPDITELKNSIRDVTNTMETCY 455 5799**********99999999999************99988765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (592 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 701 (0.0274418); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 5879.41 // Query: FUN_002106-T1 [L=103] Description: FUN_002106 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.16 11.5 0.0 0.19 11.2 0.0 1.0 1 DUF4837 Domain of unknown function (DUF4837) Domain annotation for each model (and alignments): >> DUF4837 Domain of unknown function (DUF4837) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 7.4e-06 0.19 84 157 .. 25 96 .. 18 99 .. 0.86 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 7.4e-06 DUF4837 84 arpQkvvvvkapsekelielleenkkki.inlfkkaeleelqerlkkkkslskdkklkekfgvslnvpsdykiak 157 a++Q vv+k+++++ ++ +n +k ++ fk++++e+l +++ +++++++ k+lk+ ++ +ps+y ++k FUN_002106-T1 25 AHSQVTVVIKGRQQTCKGGIVPANTDKTgMSQFKTSYIEQLPHQFPHSETKNMRKQLKQ---FKCVIPSSYHVNK 96 899***********99999999888765499***************7777777777765...6888999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1092 (0.0427481); expected 510.9 (0.02) Passed bias filter: 818 (0.0320219); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1045.33 // Query: FUN_002107-T1 [L=330] Description: FUN_002107 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-72 241.3 1.0 1.3e-71 240.8 1.0 1.1 1 rva_4 Integrase core domain 0.00014 22.1 0.1 0.0005 20.3 0.1 2.0 1 HTH_23 Homeodomain-like domain 0.0002 22.1 0.0 0.0004 21.1 0.0 1.5 1 rve Integrase core domain 0.0022 18.2 0.0 0.0053 16.9 0.0 1.6 1 HTH_38 Helix-turn-helix domain 0.0055 17.3 0.0 0.029 15.0 0.1 2.3 2 HTH_AraC Bacterial regulatory helix-turn-helix proteins 0.0099 16.1 0.0 0.019 15.2 0.0 1.5 1 HTH_8 Bacterial regulatory protein, Fis family ------ inclusion threshold ------ 0.044 13.8 0.4 0.12 12.4 0.1 1.9 2 HTH_Tnp_ISL3 Helix-turn-helix domain of transposase family 0.07 14.0 0.1 0.22 12.4 0.1 1.8 1 DUF6362 Domain of unknown function (DUF6362) 0.6 10.5 0.1 0.6 10.5 0.1 1.9 2 HTH_AsnC-type AsnC-type helix-turn-helix domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 240.8 1.0 4.6e-75 1.3e-71 1 184 [. 113 296 .. 113 302 .. 0.98 Alignments for each domain: == domain 1 score: 240.8 bits; conditional E-value: 4.6e-75 rva_4 1 vykvatPnslWhidgnmklirWrlvvhGaidgysrlivyleastnnrastvlkqflkavkkyglPsrvrsdkggenvkvallmnllrGlerssvit 96 +y+v++Pn lW id+n+kli Wr+++hG+idg+sr ivy+++ +nn a+tvl+ f+ + + +glPsrvr d+g+env+va++m + rGl+r+s+i FUN_002107-T1 113 IYNVSKPNHLWRIDSNHKLIHWRFILHGCIDGCSRAIVYFKCFNNNLATTVLQCFVLGAQGFGLPSRVRGDRGVENVNVARFMIEQRGLNRGSFIA 208 7*********************************************************************************************** PP rva_4 97 GrsvhnqrierlWrdvfkkvvsvfyslftaledseildidndihllalhivylpriqkeleefknawnnhklrteknktPlqlfvegl 184 GrsvhnqrierlW++v++ v s + +lf +e ++ild +++ +l+a h+vy iq +l+ef ++wn h+lrt ++++Pl l+ + + FUN_002107-T1 209 GRSVHNQRIERLWEEVNRVVSSFYIDLFNFMEYTGILDAHDERDLFAPHYVYKLAIQASLDEFISQWNYHGLRTMRSMSPLALWYSEM 296 *****************999999999**********************************************************9877 PP >> HTH_23 Homeodomain-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.1 1.7e-07 0.0005 13 41 .. 13 41 .. 10 45 .. 0.88 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1.7e-07 HTH_23 13 llaeGlsvkeiAellGvsrrTVyrwlkry 41 l+ G+s+++iA+ lGvs T +r ++ y FUN_002107-T1 13 LRSTGMSWTAIAKCLGVSTKTLSRRRQEY 41 4556*******************999887 PP >> rve Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 1.4e-07 0.0004 2 79 .. 117 189 .. 116 202 .. 0.86 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 1.4e-07 rve 2 trpnqlwqgDityikvpgkggklyllvivDdfsreivawalssemsaetvlaalekaiakrggvkpkiihsDngseft 79 ++pn+lw +D + ++ ++ l+ ++D +sr iv +++ +++ a tvl++ ++ +g p +++ D+g e + FUN_002107-T1 117 SKPNHLWRIDSNHKL-I-HW-RFILHGCIDGCSRAIVYFKCFNNNLATTVLQCFVLGAQGFGL--PSRVRGDRGVENV 189 58**********877.3.35.69*********************99*******9977777777..9********8877 PP >> HTH_38 Helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 1.9e-06 0.0053 11 39 .. 8 36 .. 8 37 .. 0.97 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1.9e-06 HTH_38 11 eeIerllaaGeSlraIArrLgRspsTIsR 39 e+I +l+ G+S aIA+ Lg+s+ T sR FUN_002107-T1 8 EQIDVLRSTGMSWTAIAKCLGVSTKTLSR 36 79**************************9 PP >> HTH_AraC Bacterial regulatory helix-turn-helix proteins, AraC family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.1 1e-05 0.029 1 36 [. 13 44 .. 13 44 .. 0.91 2 ? -2.5 0.0 3.2 9.1e+03 9 24 .. 56 72 .. 55 79 .. 0.68 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 1e-05 HTH_AraC 1 LrehlstnltiadiAdelgfSrsyFsrlFkketGvt 36 Lr st+++++ iA +lg+S ++sr+ +++ G+t FUN_002107-T1 13 LR---STGMSWTAIAKCLGVSTKTLSRRRQEY-GIT 44 78...9**********************6666.887 PP == domain 2 score: -2.5 bits; conditional E-value: 3.2 HTH_AraC 9 ltiadiAdelgf.Srsy 24 +++ di + f +y FUN_002107-T1 56 WNVRDILQLTPFsGETY 72 89999988776655555 PP >> HTH_8 Bacterial regulatory protein, Fis family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 6.7e-06 0.019 12 42 .] 11 41 .. 10 41 .. 0.94 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 6.7e-06 HTH_8 12 aaLertgGnkskAArlLGisRrTLyrKLkkY 42 ++L++tg + ++ A+ LG+s +TL r+ ++Y FUN_002107-T1 11 DVLRSTGMSWTAIAKCLGVSTKTLSRRRQEY 41 7899999999********************9 PP >> HTH_Tnp_ISL3 Helix-turn-helix domain of transposase family ISL3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 4.1e-05 0.12 23 46 .. 14 37 .. 12 41 .. 0.89 2 ? -3.6 0.0 4 1.1e+04 40 48 .. 221 229 .. 221 231 .. 0.83 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 4.1e-05 HTH_Tnp_ISL3 23 lllessvkavArqlgvswttVwri 46 +++ +s +a+A++lgvs++t+ r+ FUN_002107-T1 14 RSTGMSWTAIAKCLGVSTKTLSRR 37 678899***************996 PP == domain 2 score: -3.6 bits; conditional E-value: 4 HTH_Tnp_ISL3 40 wttVwrifd 48 w V+r++ FUN_002107-T1 221 WEEVNRVVS 229 899999985 PP >> DUF6362 Domain of unknown function (DUF6362) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 7.7e-05 0.22 64 91 .. 12 39 .. 5 44 .. 0.87 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 7.7e-05 DUF6362 64 WlrAeglswkeiakrlGlsrttakrrwk 91 lr++g+sw +iak lG+s++t+ rr + FUN_002107-T1 12 VLRSTGMSWTAIAKCLGVSTKTLSRRRQ 39 589********************99876 PP >> HTH_AsnC-type AsnC-type helix-turn-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.1 0.00021 0.6 18 39 .. 18 39 .. 14 41 .. 0.93 2 ? -3.8 1.0 6.1 1.7e+04 33 38 .. 102 107 .. 101 113 .. 0.66 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00021 HTH_AsnC-type 18 isfaelAeavGlSestvlrRik 39 +s++++A+ +G+S+ t rR + FUN_002107-T1 18 MSWTAIAKCLGVSTKTLSRRRQ 39 79******************76 PP == domain 2 score: -3.8 bits; conditional E-value: 6.1 HTH_AsnC-type 33 tvlrRi 38 +v+rR+ FUN_002107-T1 102 AVRRRY 107 677775 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (330 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 990 (0.0387551); expected 510.9 (0.02) Passed bias filter: 704 (0.0275592); expected 510.9 (0.02) Passed Vit filter: 73 (0.0028577); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3189.75 // Query: FUN_002108-T1 [L=117] Description: FUN_002108 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.089 12.6 0.1 0.11 12.4 0.1 1.1 1 HEAT_IPO9_c Importin-9 central HEAT repeats 0.1 12.9 0.0 0.13 12.5 0.0 1.1 1 TAGT TET-Associated Glycosyltransferase Domain annotation for each model (and alignments): >> HEAT_IPO9_c Importin-9 central HEAT repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 8.4e-06 0.11 61 109 .. 22 68 .. 10 80 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 8.4e-06 HEAT_IPO9_c 61 ewlkqkalegllaytktlfasessswkskEAaLyllnqllsdfqdvekk 109 e l+ + +++l++ ++ ++ s+s +++E+++y ++ l+d+++vek+ FUN_002108-T1 22 EKLTAAKFKSLYELNT--SEQGSNSRQQEESTIYCFEVFLKDLEEVEKD 68 5666677777777665..46778899999*****************985 PP >> TAGT TET-Associated Glycosyltransferase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 1.1e-05 0.13 93 174 .. 36 109 .. 30 114 .. 0.82 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.1e-05 TAGT 93 vrwelesgskkskksselevvfkaieetidalenvtvaalglrafssktaesepfskrlvqgavllnvdvqydfnrrfneDv 174 + +e+gs+++++++++ +f++ +++++++e+++ a+ l f+++ ++ +++++ + + ++d +n++++ D+ FUN_002108-T1 36 NT--SEQGSNSRQQEESTIYCFEVFLKDLEEVEKDGLALEDLLVFITGSDTTLNMNNN--VNLYEGKND----WNKISIQDT 109 44..78888888889************************************9999995..455556666....777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (117 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1004 (0.0393032); expected 510.9 (0.02) Passed bias filter: 595 (0.0232922); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1206.27 // Query: FUN_002109-T1 [L=459] Description: FUN_002109 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (459 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 938 (0.0367195); expected 510.9 (0.02) Passed bias filter: 612 (0.0239577); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 4572.54 // Query: FUN_002110-T1 [L=176] Description: FUN_002110 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.004 18.3 2.2 0.0086 17.3 0.6 2.2 2 THAP THAP domain ------ inclusion threshold ------ 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 SWI-SNF_Ssr4_N SWI/SNF and RSC complexes subunit Ssr4 N-term 1.4 9.6 2.9 2 9.1 0.3 2.3 2 TtuA_LIM_N 2-thiouridine synthetase TtuA, N-terminal LIM Domain annotation for each model (and alignments): >> THAP THAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 0.31 2.7e+03 22 45 .. 26 49 .. 7 60 .. 0.70 2 ! 17.3 0.6 1e-06 0.0086 28 61 .. 123 157 .. 97 171 .. 0.73 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.31 THAP 22 rfPkdkerrkkWlknikredlekk 45 + P++ + + W +++++++++ FUN_002110-T1 26 NTPREGRNLDDWQPRVQLKKERSS 49 345777778899888888755544 PP == domain 2 score: 17.3 bits; conditional E-value: 1e-06 THAP 28 errkkWlkni..kredlekkkkkksrvCskHFeee.l 61 r+ W++ + kr +++ +++ s++Cs+HF++e + FUN_002110-T1 123 MTRRLWINVVlvKRAKWTFTPT--SHLCSEHFRPEdF 157 56889*8665115555555444..69******87642 PP >> SWI-SNF_Ssr4_N SWI/SNF and RSC complexes subunit Ssr4 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 2.2e-05 0.18 55 92 .. 24 61 .. 17 81 .. 0.88 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 2.2e-05 SWI-SNF_Ssr4_N 55 yldkPqdgtvlltWqplkrlgtefasDGyvWadaeqay 92 y ++P++g l Wqp +l +e +sD +v +d+e++ FUN_002110-T1 24 YNNTPREGRNLDDWQPRVQLKKERSSDRLVLSDSESVA 61 7789******************************9875 PP >> TtuA_LIM_N 2-thiouridine synthetase TtuA, N-terminal LIM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.2 0.16 1.4e+03 11 18 .. 20 27 .. 19 28 .. 0.85 2 ? 9.1 0.3 0.00023 2 19 26 .] 146 153 .. 144 153 .. 0.89 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.16 TtuA_LIM_N 11 ihlpyhga 18 +lpy+++ FUN_002110-T1 20 HYLPYNNT 27 69****96 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00023 TtuA_LIM_N 19 aLCkeHFi 26 +LC+eHF+ FUN_002110-T1 146 HLCSEHFR 153 9******6 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (176 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1129 (0.0441965); expected 510.9 (0.02) Passed bias filter: 546 (0.021374); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1749.81 // Query: FUN_002111-T1 [L=206] Description: FUN_002111 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0074 17.3 2.5 0.34 11.9 0.1 2.6 3 DUF5344 Family of unknown function (DUF5344) ------ inclusion threshold ------ 0.014 16.2 0.0 0.027 15.2 0.0 1.4 2 FdhE_N FdhE, N-terminal 0.12 13.0 0.1 3.7 8.2 0.0 2.4 2 PrlF_antitoxin prlF antitoxin for toxin YhaV_toxin Domain annotation for each model (and alignments): >> DUF5344 Family of unknown function (DUF5344) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.98 8.3e+03 15 36 .. 4 25 .. 2 35 .. 0.71 2 ! 4.5 0.3 0.0081 69 42 76 .. 76 110 .. 56 114 .. 0.86 3 ! 11.9 0.1 4e-05 0.34 10 65 .. 147 202 .. 144 205 .. 0.92 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.98 DUF5344 15 Lselktaaqslktsvpepikgk 36 L+ l ++++ l+t+++ + +g+ FUN_002111-T1 4 LEVLWKKLSFLSTKNQLKWDGT 25 5666677777877777766665 PP == domain 2 score: 4.5 bits; conditional E-value: 0.0081 DUF5344 42 vekinelekeleellksYkalllknvedtekaVds 76 ek+ +l k+l +l+++Y+ +++ ++ ++++d+ FUN_002111-T1 76 KEKADKLRKDLINLTSTYAHPVSETLNAFQENLDN 110 58999**********************99999985 PP == domain 3 score: 11.9 bits; conditional E-value: 4e-05 DUF5344 10 eVeqkLselktaaqslktsvpepikgknsldvvekinelekeleellksYkalllk 65 +V +++l +a + ++ + e i n+ ++ + ++++e++++++l++ ll++ FUN_002111-T1 147 PVSPNVDDLAKAENFIDNAYVEAILDGNKSQYSNLVKDIETDYDSQLTQLSLLLKE 202 688999*******************************************9877765 PP >> FdhE_N FdhE, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 3.2e-06 0.027 30 127 .. 27 124 .. 11 129 .. 0.89 2 ? -3.2 0.0 1.4 1.2e+04 102 130 .. 146 174 .. 142 179 .. 0.65 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 3.2e-06 FdhE_N 30 adYLrflArlaeaQqkllaalpplepapldaealerarehgmppLdakalerdpawrelLdaLleelapeapeaaaaaleaLrkasaeelealada 125 +d LrflA e+Q + ++a+ + a + +++ h+ + L++++ e+ +++r+ L +L +++a++++e+++a e+L++ + +++e + + FUN_002111-T1 27 NDLLRFLALHLEVQPNQFRASDNGICAVFKIQNITCNFYHKAKTLQIQGKEKADKLRKDLINLTSTYAHPVSETLNAFQENLDNDDVQAREVITTG 122 577999999999998888555554478889999999999****************************************************99888 PP FdhE_N 126 ll 127 l+ FUN_002111-T1 123 LV 124 76 PP == domain 2 score: -3.2 bits; conditional E-value: 1.4 FdhE_N 102 eaaaaaleaLrkasaeelealadallage 130 ++ + ++ L ka++ +a+++a+l g+ FUN_002111-T1 146 PPVSPNVDDLAKAENFIDNAYVEAILDGN 174 56666777777777766677777777665 PP >> PrlF_antitoxin prlF antitoxin for toxin YhaV_toxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.00044 3.7 40 79 .. 14 53 .. 5 65 .. 0.83 2 ? 2.1 0.0 0.035 3e+02 79 97 .. 176 194 .. 162 195 .. 0.83 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.00044 PrlF_antitoxin 40 laraadeeddpvlgaflaflardikkePerlravdaslvq 79 l+ +++ + d + +++l+fla ++ +P++ ra d+++ + FUN_002111-T1 14 LSTKNQLKWDGTKNDLLRFLALHLEVQPNQFRASDNGICA 53 5666677779999*******************99987754 PP == domain 2 score: 2.1 bits; conditional E-value: 0.035 PrlF_antitoxin 79 qrlkslvagvdvdldaels 97 ++ +lv++++ d d++l+ FUN_002111-T1 176 SQYSNLVKDIETDYDSQLT 194 57789**********9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (206 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1148 (0.0449403); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2002.34 // Query: FUN_002112-T1 [L=236] Description: FUN_002112 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (236 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 891 (0.0348796); expected 510.9 (0.02) Passed bias filter: 725 (0.0283813); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2299.46 // Query: FUN_002113-T1 [L=116] Description: FUN_002113 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 554 (0.0216872); expected 510.9 (0.02) Passed bias filter: 354 (0.0138579); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.40s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1177.85 // Query: FUN_002114-T1 [L=119] Description: FUN_002114 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0056 17.1 0.3 0.0071 16.8 0.3 1.2 1 SmpB SmpB protein ------ inclusion threshold ------ 0.017 15.2 0.1 0.022 14.8 0.1 1.1 1 DUF2982 Protein of unknown function (DUF2982) 0.053 14.3 2.0 9.6 7.1 0.0 2.3 2 LPP Lipoprotein leucine-zipper 0.054 14.1 0.4 0.25 12.0 0.1 2.0 2 Calmod_bind_C Calmodulin binding protein C-terminal domain 0.16 13.1 1.5 8.4 7.6 0.1 2.1 2 SlyX SlyX 0.7 10.9 5.4 6.7 7.8 5.4 2.1 1 NPV_P10 Nucleopolyhedrovirus P10 protein Domain annotation for each model (and alignments): >> SmpB SmpB protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.3 1.7e-06 0.0071 26 77 .. 20 72 .. 8 86 .. 0.80 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 1.7e-06 SmpB 26 tEvKslragkvnlkdsyvkikkgelfllnlhiseyekgnvfn..hepkrkrkLL 77 Ev s++++++ l+d + +i+k+ +f+ + +++e++++ + n ++ +rkL+ FUN_002114-T1 20 IEVVSVKTKQIALDDNFTSIEKNTVFVDE-QVQELTTKAYKNsnDVSDTHRKLM 72 69********************9999865.778887766655324456677776 PP >> DUF2982 Protein of unknown function (DUF2982) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.1 5.1e-06 0.022 29 118 .. 8 98 .. 4 104 .. 0.85 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 5.1e-06 DUF2982 29 vprvekglelvelpyvGiklkdldefldsispRLatkLLteQ.rpLlllaakkaaeeeeleedllelekylsanGerykGvlAmfanrmek 118 v + ++++ +e+++v +k k+++ + s t + eQ ++L+++a+k++++ ++++ +l+ le+y + + +++G+ f+ r e FUN_002114-T1 8 VKELQSKVTALEIEVVSVKTKQIALDDNFTSIEKNTVFVDEQvQELTTKAYKNSNDVSDTHRKLMYLEAYSRRENLKFEGIPETFGMRKED 98 556788899999**********987777777777899999**4457777788799999****************************99875 PP >> LPP Lipoprotein leucine-zipper # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.7 0.5 0.0029 12 2 28 .. 1 27 [. 1 35 [. 0.85 2 ? 7.1 0.0 0.0023 9.6 7 31 .. 48 72 .. 46 86 .. 0.83 Alignments for each domain: == domain 1 score: 6.7 bits; conditional E-value: 0.0029 LPP 2 vdqLssqVseLkskvdqlasdvnaaka 28 +++L V eL+skv +l +v ++k+ FUN_002114-T1 1 MEELNVAVKELQSKVTALEIEVVSVKT 27 7889999*********99988888876 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0023 LPP 7 sqVseLkskvdqlasdvnaakadvq 31 +qV+eL k + ++dv++ ++ FUN_002114-T1 48 EQVQELTTKAYKNSNDVSDTHRKLM 72 69***************99876655 PP >> Calmod_bind_C Calmodulin binding protein C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 5.9e-05 0.25 27 59 .. 32 64 .. 21 67 .. 0.90 2 ? -0.1 0.0 0.35 1.5e+03 50 60 .. 74 84 .. 70 85 .. 0.82 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.9e-05 Calmod_bind_C 27 iggqyvslekLsetqkayvekLvkeAYenwdql 59 ++ ++s+ek + +v++L +AY+n +++ FUN_002114-T1 32 LDDNFTSIEKNTVFVDEQVQELTTKAYKNSNDV 64 6888999999999999**************998 PP == domain 2 score: -0.1 bits; conditional E-value: 0.35 Calmod_bind_C 50 keAYenwdqle 60 eAY+++++l+ FUN_002114-T1 74 LEAYSRRENLK 84 69****99986 PP >> SlyX SlyX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.2 0.0094 40 20 46 .. 2 28 .. 1 35 [. 0.81 2 ? 7.6 0.1 0.002 8.4 2 44 .. 33 75 .. 32 87 .. 0.90 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.0094 SlyX 20 eeLndvvaeqqreidrlqrqlrllaer 46 eeLn +v e q ++++l+ ++ ++ + FUN_002114-T1 2 EELNVAVKELQSKVTALEIEVVSVKTK 28 899999999999999999998777766 PP == domain 2 score: 7.6 bits; conditional E-value: 0.002 SlyX 2 eerleeLEiklafqedtieeLndvvaeqqreidrlqrqlrlla 44 ++ ++ +E f ++ ++eL ++ +++ +r+l l+ FUN_002114-T1 33 DDNFTSIEKNTVFVDEQVQELTTKAYKNSNDVSDTHRKLMYLE 75 788999**************************99999998886 PP >> NPV_P10 Nucleopolyhedrovirus P10 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.8 5.4 0.0016 6.7 12 60 .. 7 52 .. 3 84 .. 0.76 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0016 NPV_P10 12 dikavddkVdalqqqvddleenlpdvtelnekLdaqsaqLaelqtkvee 60 ++k++++kV+al+ +v +++++ l +++ ++ ++ ++++v+e FUN_002114-T1 7 AVKELQSKVTALEIEVVSVKTKQIA---LDDNFTSIEKNTVFVDEQVQE 52 89**************999987655...444444444444444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1653 (0.0647093); expected 510.9 (0.02) Passed bias filter: 792 (0.0310041); expected 510.9 (0.02) Passed Vit filter: 100 (0.00391466); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1202.08 // Query: FUN_002115-T1 [L=236] Description: FUN_002115 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-52 176.7 5.8 2.1e-52 176.7 5.8 1.5 2 Fra10Ac1 Folate-sensitive fragile site protein Fra10Ac1 Domain annotation for each model (and alignments): >> Fra10Ac1 Folate-sensitive fragile site protein Fra10Ac1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 0.48 1.2e+04 91 111 .. 61 83 .. 57 92 .. 0.53 2 ! 176.7 5.8 8.3e-57 2.1e-52 1 118 [] 111 227 .. 111 227 .. 0.98 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 0.48 Fra10Ac1 91 FaYk..ekgekknalvkvrlCee 111 F+Y e +k++ +++ + ++ FUN_002115-T1 61 FEYSreEGRIQKREFLQLDAYSR 83 55532144456666665555444 PP == domain 2 score: 176.7 bits; conditional E-value: 8.3e-57 Fra10Ac1 1 tdldvlkeehkFlrddeeeeeekswekrlakkyydklfkeyaiadlsrykegkialRWrtekevvsGkGqftCgnkkCeekeelksfevnFaYkek 96 +dldv+k+eh+Fl+++++++e+ +wek+lakkyy+klf+ey+i dl+ yke+kialRWr+ekevv+GkGqf+Cg+k+C+e+e+l+s+evnF+Y e+ FUN_002115-T1 111 SDLDVIKQEHRFLWKEKDNSES-TWEKHLAKKYYEKLFREYCISDLRYYKENKIALRWRIEKEVVDGKGQFICGDKRCAETEGLRSWEVNFGYSEH 205 599*************999987.************************************************************************* PP Fra10Ac1 97 gekknalvkvrlCeecakklny 118 gekk++l+k+rlC++c++klny FUN_002115-T1 206 GEKKSTLIKLRLCPDCSYKLNY 227 ********************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (236 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 889 (0.0348013); expected 510.9 (0.02) Passed bias filter: 499 (0.0195342); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2404.27 // Query: FUN_002116-T1 [L=277] Description: FUN_002116 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (277 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 549 (0.0214915); expected 510.9 (0.02) Passed bias filter: 366 (0.0143277); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2766.42 // Query: FUN_002117-T1 [L=317] Description: FUN_002117 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.07 13.7 0.1 0.13 12.8 0.1 1.4 1 RBD_ZCCHC3_1st ZCCHC3, first RNA-binding domain 2.3 9.1 3.8 0.75 10.7 0.8 1.7 2 TopBP1_BRCT0 TopBP1, BRCT0 domain Domain annotation for each model (and alignments): >> RBD_ZCCHC3_1st ZCCHC3, first RNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 1e-05 0.13 21 66 .. 118 160 .. 104 164 .. 0.85 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1e-05 RBD_ZCCHC3_1st 21 vvrklLleslgftpedvyalialpgskefDVsFkseellekfweky 66 + +k++ s+g+++++v +++++ + DV+F ++ + f++k+ FUN_002117-T1 118 ILDKIV--SIGIQRKHVKCIQRFC-TGQVDVTFCRKTDRDLFLSKV 160 455666..99**************.899**********99999886 PP >> TopBP1_BRCT0 TopBP1, BRCT0 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.1 1.3 1.6e+04 62 82 .. 131 151 .. 114 156 .. 0.53 2 ? 10.7 0.8 5.9e-05 0.75 8 68 .. 243 303 .. 239 308 .. 0.92 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.3 TopBP1_BRCT0 62 hlkklgcrivsplvvlfclkk 82 h+k + + v fc k FUN_002117-T1 131 HVKCIQRFCTGQVDVTFCRKT 151 444443333333346666665 PP == domain 2 score: 10.7 bits; conditional E-value: 5.9e-05 TopBP1_BRCT0 8 saeksevavkayeaikelqsekylqtvdeeealelkekdkslyvfdsfssvafshlkklgc 68 s e+se +++ e e+ s++ ++ vdee+ + +d + ++ ++ +++h +k g FUN_002117-T1 243 SDESSEEHAETSENSSEVLSDDTVHEVDEEASIAEVSDDIEQFTSSESDTDSLHHQRKRGA 303 66789999999999********************99*********************9885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1239 (0.0485026); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3142.57 // Query: FUN_002118-T1 [L=119] Description: FUN_002118 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00019 21.1 1.8 0.00025 20.7 1.8 1.0 1 Rod_CreS Crescentin, rod domain 0.0083 16.4 1.1 0.011 16.0 1.1 1.2 1 Bacillus_HBL Bacillus haemolytic enterotoxin (HBL) 0.01 15.8 2.3 0.42 10.5 0.2 2.0 2 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin prote ------ inclusion threshold ------ 0.011 15.6 4.3 0.013 15.4 4.3 1.1 1 GAS Growth-arrest specific micro-tubule bindin 0.013 15.7 2.2 0.017 15.3 2.2 1.2 1 CCDC113_CCDC96_CC CCDC113/CCDC96, coiled-coil 0.016 15.7 2.4 0.019 15.5 2.4 1.1 1 CENP-F_leu_zip Leucine-rich repeats of kinetochore protei 0.048 14.6 1.5 0.058 14.3 1.5 1.4 1 APG6_N Apg6 coiled-coil region 0.065 13.8 1.1 0.082 13.4 1.1 1.1 1 DUF1664 Protein of unknown function (DUF1664) 0.17 12.8 0.3 0.25 12.3 0.3 1.3 1 Acetyltransf_11 Udp N-acetylglucosamine O-acyltransferase; 0.17 12.9 0.8 0.71 10.9 0.1 1.9 2 FOXP-CC FOXP coiled-coil domain Domain annotation for each model (and alignments): >> Rod_CreS Crescentin, rod domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 1.8 9.8e-08 0.00025 22 88 .. 50 116 .. 45 118 .. 0.93 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 9.8e-08 Rod_CreS 22 sdklrrevagltrrlsaaereleelsarlakleaalkeaeaakeelrielrektalaealErqlkae 88 + lr+ ++l+++ ++ + l++l ++++l+++l e +a+ eel+ +r+k ++++Er+ ++ FUN_002118-T1 50 FAYLRKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEGDADMEELANFVRTKDKVIKNMERRILQA 116 56799999*******************************************************9876 PP >> Bacillus_HBL Bacillus haemolytic enterotoxin (HBL) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 1.1 4.4e-06 0.011 107 171 .. 53 117 .. 44 119 .] 0.77 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 4.4e-06 Bacillus_HBL 107 lekLqeeiqqnqkevkqlieeLkklklklakdsknFktdvdeltsilagdsgvisqlkneiedlq 171 l k ++++q+ k v + +++Lk +++la d ++ ++d++el + + ++++vi++++ +i +++ FUN_002118-T1 53 LRKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEGDADMEELANFVRTKDKVIKNMERRILQAK 117 45555555555555555555555556779********************************9886 PP >> BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.2 0.00016 0.42 65 89 .. 51 75 .. 44 82 .. 0.87 2 ! 5.9 0.3 0.0042 11 32 66 .. 82 116 .. 75 119 .] 0.85 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00016 BAR_3_WASP_bdg 65 efvkklagplkkeyqkiGkafkals 89 + +k+ l+ke++++Gka+++l+ FUN_002118-T1 51 AYLRKVYQNLQKEHKRVGKALQNLK 75 57899999***************97 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0042 BAR_3_WASP_bdg 32 elDlqeveqkveafkkftkklddsvkelltvanef 66 Dl+e + +e++ +f+++ d+ +k+++ ++ + FUN_002118-T1 82 ARDLAEGDADMEELANFVRTKDKVIKNMERRILQA 116 56999***********************9987665 PP >> GAS Growth-arrest specific micro-tubule binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 4.3 5e-06 0.013 46 96 .. 54 105 .. 48 119 .] 0.78 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 5e-06 GAS 46 ekelseieqenkrlkepLekaeeeveeLkkqleeyekdkqslknl.karlke 96 +k +++++e kr + L++++ ++eeL ++l+e + d ++l+n +++ k+ FUN_002118-T1 54 RKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEGDADMEELANFvRTKDKV 105 67889999***************************99999999962333333 PP >> CCDC113_CCDC96_CC CCDC113/CCDC96, coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 2.2 6.8e-06 0.017 105 171 .. 48 116 .. 42 119 .] 0.86 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 6.8e-06 CCDC113_CCDC96_CC 105 eklaklrkelyevklerdklrkqnkklkkqggllrvPaLl..eDYdktkeeveekrksvkkLrrkvkil 171 + +a lrk +++++e++++ k ++lk q ++l ++ D ++ ++v k k++k+++r++ ++ FUN_002118-T1 48 QSFAYLRKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEgdADMEELANFVRTKDKVIKNMERRILQA 116 6678899***************************98766533589999999999*******99998776 PP >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 2.4 7.3e-06 0.019 56 121 .. 52 117 .. 45 119 .] 0.91 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 7.3e-06 CENP-F_leu_zip 56 tlkaeieelaeelrqleldLvtlrsekeeLtkeLqkkqervseLeslnsslenlleekEqekvqmk 121 l++ ++l++e ++ L++l+ ++eeL ++L + + ++eL + + +++++ E q k FUN_002118-T1 52 YLRKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEGDADMEELANFVRTKDKVIKNMERRILQAK 117 5788899****************************************************9877765 PP >> APG6_N Apg6 coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 1.5 2.3e-05 0.058 47 95 .. 49 97 .. 2 118 .. 0.69 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 2.3e-05 APG6_N 47 eleelekeleklekeeeelleeLeelekekeeldaelealeeelealde 95 + + l+k +++l+ke ++ + L++l+ ++eel+++l++ ++ +e+l + FUN_002118-T1 49 SFAYLRKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEGDADMEELAN 97 4455666677777777777777777777777777777777777777654 PP >> DUF1664 Protein of unknown function (DUF1664) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 1.1 3.2e-05 0.082 55 118 .. 51 114 .. 45 118 .. 0.91 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 3.2e-05 DUF1664 55 eslaatKkeLsqridrvdkkldeqkeiskeikeevtevredvsnikedvksvkeaveglesklk 118 + l+++ ++L+++ +rv+k l++ k +e+ ++++e d++++ + v++ +++++++e ++ FUN_002118-T1 51 AYLRKVYQNLQKEHKRVGKALQNLKVQNEELARDLAEGDADMEELANFVRTKDKVIKNMERRIL 114 568888999***************************************************9985 PP >> Acetyltransf_11 Udp N-acetylglucosamine O-acyltransferase; Domain 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.3 9.8e-05 0.25 34 78 .. 51 103 .. 47 112 .. 0.88 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 9.8e-05 Acetyltransf_11 34 kalkkayrllyrsgltleealeel........eeeaeespevqelldFirssk 78 + l+k+y+ l ++++++ +al++l ++ ae +++++el +F+r+++ FUN_002118-T1 51 AYLRKVYQNLQKEHKRVGKALQNLkvqneelaRDLAEGDADMEELANFVRTKD 103 679*********************99999998777888999********9866 PP >> FOXP-CC FOXP coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.1 0.00028 0.71 12 46 .. 46 80 .. 42 87 .. 0.89 2 ? 0.5 0.0 0.48 1.2e+03 40 58 .. 99 117 .. 80 118 .. 0.75 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00028 FOXP-CC 12 CekvledveeflkHlqseHslddkstaqlrvQmev 46 C + + +++ ++ lq+eH+ k+ ++l+vQ e FUN_002118-T1 46 CLQSFAYLRKVYQNLQKEHKRVGKALQNLKVQNEE 80 777888889999********************985 PP == domain 2 score: 0.5 bits; conditional E-value: 0.48 FOXP-CC 40 lrvQmevvqqlekqLvkek 58 +r +v++++e+++ + k FUN_002118-T1 99 VRTKDKVIKNMERRILQAK 117 6778889999998877655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1949 (0.0762967); expected 510.9 (0.02) Passed bias filter: 1139 (0.044588); expected 510.9 (0.02) Passed Vit filter: 157 (0.00614602); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.28u 0.45s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 1189.99 // Query: FUN_002119-T1 [L=179] Description: FUN_002119 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.21 11.6 0.2 0.5 10.3 0.2 1.6 1 HTH_AT3G52170 Helix-turn-helix domain in AT3G52170-like prot Domain annotation for each model (and alignments): >> HTH_AT3G52170 Helix-turn-helix domain in AT3G52170-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.2 2e-05 0.5 26 48 .. 125 147 .. 125 149 .. 0.94 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 2e-05 HTH_AT3G52170 26 tlsevrkeVGGsyyvvreIlqel 48 t+s+++++VGG ++ ++qe+ FUN_002119-T1 125 TVSKLKNNVGGNRSGLKRVVQEI 147 6899******************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (179 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 553 (0.0216481); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1839.35 // Query: FUN_002120-T1 [L=101] Description: FUN_002120 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1236 (0.0483852); expected 510.9 (0.02) Passed bias filter: 730 (0.028577); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1024.71 // Query: FUN_002121-T1 [L=214] Description: FUN_002121 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (214 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 607 (0.023762); expected 510.9 (0.02) Passed bias filter: 460 (0.0180074); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.43s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2153.10 // Query: FUN_002122-T1 [L=142] Description: FUN_002122 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 509 (0.0199256); expected 510.9 (0.02) Passed bias filter: 351 (0.0137405); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.35s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1460.59 // Query: FUN_002127-T1 [L=217] Description: FUN_002127 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.012 16.0 1.0 0.018 15.5 1.0 1.2 1 DUF3439 Domain of unknown function (DUF3439) 0.59 9.8 2.4 0.78 9.4 2.4 1.1 1 Med3 Mediator complex subunit 3 fungal Domain annotation for each model (and alignments): >> DUF3439 Domain of unknown function (DUF3439) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 1.0 1.4e-06 0.018 26 83 .. 38 93 .. 22 103 .. 0.76 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.4e-06 DUF3439 26 vdpdsakcsgsgkpvrsiicpttttttttttttmpttttlptttkmsmvkvplvppea 83 d++ a s +s++c t t t tt++tt +t l +t +v p+ e+ FUN_002127-T1 38 EDDNIADSS--QAGSQSLVCITDTFTFTTSATTTTATPGLVVATVSPLVSFPVATQES 93 333334444..445689*****999999999999999999999999999999887775 PP >> Med3 Mediator complex subunit 3 fungal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 2.4 6.1e-05 0.78 138 208 .. 56 129 .. 38 146 .. 0.71 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 6.1e-05 Med3 138 vastpsaaaatPtttatPgastktaaksvpaptata.tigtptvnnstaaaastatttsstakkPrk..Prqtk 208 ++ t + ++++ tttatPg t++ v+ p at ++ p+ s + st + t ak+ r Pr+ FUN_002127-T1 56 ITDTFTFTTSATTTTATPGLVVATVSPLVSFPVATQeSVAGPSCSFSGGSFYSTRQRTLVLAKRARVepPRKRP 129 3445566677778899******************9757999*************99999999986632233322 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (217 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 620 (0.0242709); expected 510.9 (0.02) Passed bias filter: 425 (0.0166373); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.43s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 2181.23 // Query: FUN_002128-T1 [L=167] Description: FUN_002128 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-07 31.3 0.3 6.4e-07 30.0 0.3 1.7 1 HTH_21 HTH-like domain Domain annotation for each model (and alignments): >> HTH_21 HTH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.0 0.3 2.5e-11 6.4e-07 3 59 .. 24 80 .. 22 81 .. 0.91 Alignments for each domain: == domain 1 score: 30.0 bits; conditional E-value: 2.5e-11 HTH_21 3 ddellelIkeifeesrgtYGyRritaeLrreggirvnrkrVaRLMrelgLrakrrrk 59 +d + elIk+ + + GyR i+++Lr +++++v r +Va +M+e + ++++ r+ FUN_002128-T1 24 EDIVRELIKQEMQGAGSLAGYRYIWHALRLRHYVNVPRSQVASIMKEIDPQGVQERR 80 5667889******9*9*******************************9988888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 917 (0.0358974); expected 510.9 (0.02) Passed bias filter: 768 (0.0300646); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1673.75 // Query: FUN_002129-T1 [L=115] Description: FUN_002129 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-10 39.3 0.0 8.5e-10 39.2 0.0 1.1 1 HECT HECT-domain (ubiquitin-transferase) Domain annotation for each model (and alignments): >> HECT HECT-domain (ubiquitin-transferase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.2 0.0 3.3e-14 8.5e-10 234 306 .. 41 114 .. 14 115 .] 0.91 Alignments for each domain: == domain 1 score: 39.2 bits; conditional E-value: 3.3e-14 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx RF HECT 234 klLkFvTgssrlPlgGfkslpkltIqkksg..kdddrLPtahTCfnlLklp.eYsskeilkekLliAieegegFgl 306 +l+k++Tg s++P Gf +k+t+++++g + Pta+TC ++klp + +++++++++++ A+ee+ gFgl FUN_002129-T1 41 DLIKWMTGASQIPPLGFP--KKFTVEFVHGctAGCCCRPTASTCDITIKLPvHINTEQNMEDMITSAVEESYGFGL 114 79****************..89*****99976455566*************7789999****************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 643 (0.0251713); expected 510.9 (0.02) Passed bias filter: 438 (0.0171462); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1146.61 // Query: FUN_002130-T1 [L=569] Description: FUN_002130 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0028 18.3 3.2 0.0028 18.3 3.2 2.0 2 DZR Double zinc ribbon 0.0068 16.6 6.8 0.017 15.3 6.8 1.7 1 Zn_Ribbon_1 zinc-ribbon domain ------ inclusion threshold ------ 0.91 9.9 6.9 0.14 12.5 2.5 1.9 2 DZR_2 Double zinc ribbon domain 1.5 9.3 9.3 0.61 10.5 0.3 2.7 3 Zn_ribbon_Nudix Nudix N-terminal Domain annotation for each model (and alignments): >> DZR Double zinc ribbon # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 3.2 4.4e-07 0.0028 1 23 [. 3 25 .. 2 36 .. 0.80 2 ? -2.3 0.2 1.2 7.6e+03 27 31 .. 318 322 .. 309 339 .. 0.59 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 4.4e-07 DZR 1 CpqCgaenpsdakfCeeCgtklk 23 C+ Cg++ p +ak+C++Cg++lk FUN_002130-T1 3 CSSCGQNCPLEAKYCHKCGERLK 25 78888888888888888888776 PP == domain 2 score: -2.3 bits; conditional E-value: 1.2 DZR 27 CpkCg 31 Cp C FUN_002130-T1 318 CPICF 322 33332 PP >> Zn_Ribbon_1 zinc-ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 6.8 2.7e-06 0.017 1 22 [. 2 23 .. 2 24 .. 0.94 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 2.7e-06 Zn_Ribbon_1 1 fCpnCGaenpdgakFCpkCGap 22 fC+ CG+ p +ak+C kCG FUN_002130-T1 2 FCSSCGQNCPLEAKYCHKCGER 23 9*******************65 PP >> DZR_2 Double zinc ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 2.5 2.2e-05 0.14 23 48 .. 2 26 .. 1 35 [. 0.88 2 ? -2.3 0.1 0.89 5.7e+03 9 16 .. 317 324 .. 313 340 .. 0.64 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 2.2e-05 DZR_2 23 lCaaCrkelefieeplCkrcGkplee 48 +C++C ++ ++e+++C++cG+ l++ FUN_002130-T1 2 FCSSCGQNC-PLEAKYCHKCGERLKQ 26 7********.***********99865 PP == domain 2 score: -2.3 bits; conditional E-value: 0.89 DZR_2 9 rCllCgai 16 +C++C + FUN_002130-T1 317 SCPICFSL 324 47777554 PP >> Zn_ribbon_Nudix Nudix N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 1.4 0.016 1e+02 2 9 .. 2 9 .. 1 13 [. 0.85 2 ? 10.5 0.3 9.6e-05 0.61 1 17 [. 15 31 .. 15 34 .. 0.90 3 ? -3.7 0.0 2.7 1.7e+04 17 28 .. 309 321 .. 307 323 .. 0.68 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.016 Zn_ribbon_Nudix 2 FCsqCGgp 9 FCs+CG+ FUN_002130-T1 2 FCSSCGQN 9 9*****86 PP == domain 2 score: 10.5 bits; conditional E-value: 9.6e-05 Zn_ribbon_Nudix 1 kFCsqCGgpvelripeg 17 k+C +CG+++++ + eg FUN_002130-T1 15 KYCHKCGERLKQYVTEG 31 8**********998887 PP == domain 3 score: -3.7 bits; conditional E-value: 2.7 Zn_ribbon_Nudix 17 gDnrpRlv.CtaC 28 +++++Rl+ C+ C FUN_002130-T1 309 EEQQERLMsCPIC 321 5677887547766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (569 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1168 (0.0457232); expected 510.9 (0.02) Passed bias filter: 713 (0.0279115); expected 510.9 (0.02) Passed Vit filter: 79 (0.00309258); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 5536.50 // Query: FUN_002131-T1 [L=151] Description: FUN_002131 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (151 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 694 (0.0271677); expected 510.9 (0.02) Passed bias filter: 551 (0.0215698); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1494.63 // Query: FUN_002132-T1 [L=79] Description: FUN_002132 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (79 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 727 (0.0284596); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.21u 0.42s 00:00:00.63 Elapsed: 00:00:00.38 # Mc/sec: 829.36 // Query: FUN_002133-T1 [L=208] Description: FUN_002133 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-15 56.4 0.0 1.1e-14 55.5 0.0 1.5 1 OTU OTU-like cysteine protease ------ inclusion threshold ------ 0.24 12.1 0.1 0.45 11.2 0.1 1.4 1 DUF6074 Family of unknown function (DUF6074) Domain annotation for each model (and alignments): >> OTU OTU-like cysteine protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.5 0.0 8.4e-19 1.1e-14 1 99 [. 38 139 .. 38 162 .. 0.81 Alignments for each domain: == domain 1 score: 55.5 bits; conditional E-value: 8.4e-19 OTU 1 pgDGnCLyrsisqqlwlrsdegrklkvqeLreklaeyvr.....ehkeefepfledeetgkyikeiektaawggelelfalahiLrrpIivlkses 91 p+DGnC+++++++q++ r + +++ +Lr+ ++e +r k+ +++fl ++ + y+ +++ ++ wg+++ l lah+L r+I +++s + FUN_002133-T1 38 PSDGNCMFHAVADQMN-RL-GEFGHSHTTLRHLAVETLRkgshgISKDYIAMFLPNNDMNAYLTDMRMNGTWGDHIVLVSLAHALGRTIRIVSSLG 131 69*************7.44.35556799999999999997776545556666666665559******************************99988 PP OTU 92 geelvglk 99 +++ v +k FUN_002133-T1 132 DSHDVIVK 139 88766544 PP >> DUF6074 Family of unknown function (DUF6074) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 3.5e-05 0.45 26 79 .. 5 59 .. 2 63 .. 0.86 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 3.5e-05 DUF6074 26 kktgdeaeaywrrecralaaeLarlGlse.eeireevlaFqdaVqaelerlsser 79 kk++ + ++++++ +++l+++ ++ Gl+ + i + + ++aV ++++rl +++ FUN_002133-T1 5 KKQSIAEDEAYQQNVAQLFQNVRKSGLQMrNNIPSDGNCMFHAVADQMNRLGEFG 59 56777889999****************96268999**************997765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 890 (0.0348405); expected 510.9 (0.02) Passed bias filter: 759 (0.0297123); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.43s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2071.86 // Query: FUN_002136-T1 [L=114] Description: FUN_002136 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (114 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 549 (0.0214915); expected 510.9 (0.02) Passed bias filter: 431 (0.0168722); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1170.19 // Query: FUN_002137-T1 [L=252] Description: FUN_002137 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 5 7.8 7.5 6.6 7.4 0.2 3.2 3 DUF7623 Domain of unknown function (DUF7623) Domain annotation for each model (and alignments): >> DUF7623 Domain of unknown function (DUF7623) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.1 0.2 5e+03 31 48 .. 23 41 .. 13 45 .. 0.59 2 ? 2.9 0.8 0.0069 1.8e+02 5 40 .. 49 83 .. 44 93 .. 0.74 3 ? 7.4 0.2 0.00026 6.6 22 48 .. 222 248 .. 221 250 .. 0.90 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.2 DUF7623 31 lkkdpk.knaaaiadleda 48 l++d + +aa++a+ +++ FUN_002137-T1 23 LMEDGRfSHAARLAARQER 41 4455555566666655555 PP == domain 2 score: 2.9 bits; conditional E-value: 0.0069 DUF7623 5 PeGvpledLpLdeDpeFreleaerrklkkdpkknaa 40 P++v +e++++ D++ r+ +++r+l+ +p ++ FUN_002137-T1 49 PDDVAVEQVKPV-DRKLRRAVKKLRQLQTQPLTAEE 83 666777777765.99**************9954444 PP == domain 3 score: 7.4 bits; conditional E-value: 0.00026 DUF7623 22 releaerrklkkdpkknaaaiadleda 48 re+ ++rr+l++d ++++ le++ FUN_002137-T1 222 REMDKRRRQLDPDGPSASRELKGLEQQ 248 6899**********888888**99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (252 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 928 (0.036328); expected 510.9 (0.02) Passed bias filter: 638 (0.0249755); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2522.65 // Query: FUN_002138-T1 [L=335] Description: FUN_002138 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (335 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1199 (0.0469368); expected 510.9 (0.02) Passed bias filter: 700 (0.0274026); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3354.65 // Query: FUN_002139-T1 [L=715] Description: FUN_002139 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-18 67.5 0.0 2.6e-18 66.5 0.0 1.5 1 Transposase_21 Transposase family tnp2 2.5e-06 27.7 0.2 9.9e-05 22.4 0.0 2.2 2 DUF1258 Protein of unknown function (DUF1258) Domain annotation for each model (and alignments): >> Transposase_21 Transposase family tnp2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.5 0.0 2.1e-22 2.6e-18 1 172 [. 350 518 .. 350 553 .. 0.83 Alignments for each domain: == domain 1 score: 66.5 bits; conditional E-value: 2.1e-22 Transposase_21 1 dgllrhPadseaWkkf.drkhpefaedsrnvrlglatdGfnPfgslsssysiWpvllvpynlPPWlcmkrksfllsllipGpksPGkdidvfleP 94 d+++ d++ W++f +k + f + +rn+ +++ d f Pf+ + s+ + lv +nlP + +k ++++++ +ip ++ k ++ fl P FUN_002139-T1 350 DNIMADIYDGSIWRDFlKYKGNDFLNAPRNLAFAINVDWFQPFKRRN-DRSVGAIYLVLLNLPREQRFKWENIIVAGIIPEMSKEPKSLNTFLAP 443 67788889*******84678899********************9866.579******************************************** PP Transposase_21 95 lvdellelweeGvetydaskkekfelraallwtindfPalsllsGlstkg.yeacptcnkntesirlknskkicylghr 172 +vdel+ lw+ Gv+ + + ++ ++ r all + d Pa+ +l G + ++ + +c +c k + s+k+ y g FUN_002139-T1 444 IVDELQALWK-GVKLMTSQSRIPLTYRGALLLASADLPAIRKLCGFKGHSaHRGCSKCFKY---FPGTFSEKTDYSGFD 518 *********9.**********************************9876514567777553...333445666666654 PP >> DUF1258 Protein of unknown function (DUF1258) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.6 0.01 1.3e+02 4 44 .. 242 282 .. 240 290 .. 0.74 2 ! 22.4 0.0 7.8e-09 9.9e-05 111 220 .. 395 513 .. 353 534 .. 0.71 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.01 DUF1258 4 klWnykkknfsthkfcnkcGksvassekckl.cggkvlkfvr 44 k n ++ nf +c kc s+ + e c + gg++++ + FUN_002139-T1 242 KFVNLNRDNFVKFAVCPKCA-SLYQLESCTRlVGGQIVSNIC 282 566899*************9.677788886516778887654 PP == domain 2 score: 22.4 bits; conditional E-value: 7.8e-09 DUF1258 111 GnkkklWPvslilvdlPtaemqkstnillegiv.ecvenPstvlWnallPli......lsdlesktGkva.kvkfkakivtltadqPakrslfGlk 198 n + + + l+l++lP+ + k ni++ gi+ e +++P l l P++ + ++ t + + + ++ ++ +ad Pa r l G+k FUN_002139-T1 395 RNDRSVGAIYLVLLNLPREQRFKWENIIVAGIIpEMSKEPK-SLNTFLAPIVdelqalWKGVKLMTSQSRiPLTYRGALLLASADLPAIRKLCGFK 489 4666788899**********************945666665.4555555554221111333333333332124567777889************** PP DUF1258 199 ahqseksc..fyclstgtlykkrg 220 +h +++ c ++ +gt+ k++ FUN_002139-T1 490 GHSAHRGCskCFKYFPGTFSEKTD 513 ******993344556888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (715 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 632 (0.0247407); expected 510.9 (0.02) Passed bias filter: 508 (0.0198865); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.38s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 7051.27 // Query: FUN_002140-T1 [L=222] Description: FUN_002140 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (222 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 502 (0.0196516); expected 510.9 (0.02) Passed bias filter: 438 (0.0171462); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2233.58 // Query: FUN_002141-T1 [L=364] Description: FUN_002141 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (364 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 543 (0.0212566); expected 510.9 (0.02) Passed bias filter: 478 (0.0187121); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 3522.48 // Query: FUN_002142-T1 [L=167] Description: FUN_002142 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 363 (0.0142102); expected 510.9 (0.02) Passed bias filter: 314 (0.012292); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1711.08 // Query: FUN_002143-T1 [L=463] Description: FUN_002143 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0017 18.7 0.4 0.011 16.0 0.1 2.5 2 HIRAN HIRAN domain ------ inclusion threshold ------ 0.033 14.0 0.1 0.056 13.2 0.1 1.3 1 Beta-prop_BBS7 BBS7 beta-propeller 0.07 14.0 0.1 24 5.9 0.0 2.4 2 DUF1611_N Domain of unknown function (DUF1611_N) Rossma Domain annotation for each model (and alignments): >> HIRAN HIRAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.1 1.3e-06 0.011 24 69 .. 29 100 .. 7 129 .. 0.73 2 ? -2.7 0.0 0.88 7.5e+03 9 36 .. 384 413 .. 382 418 .. 0.70 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 1.3e-06 HIRAN 24 eivklvrepqnpydsnavrvyt..edge.......................eiGylprevakilapll.dsg 69 ++ l+rep n+ d+nav+v ++g+ ++G++p+ +a++++ l +s+ FUN_002143-T1 29 SEHSLRREPGNEVDKNAVAVVQetQSGNttrassqaeplnthpneiavsmeVVGHVPKLMAQWVKFLKrASN 100 56679****************97644447778888899999999999999788**********987764222 PP == domain 2 score: -2.7 bits; conditional E-value: 0.88 HIRAN 9 vgtrYysg..trklkigeivklvrepqnpy 36 ++ rY++ ++ ++i+ ++++ ++ +n + FUN_002143-T1 384 WSSRYIPEtaYQHVDINCDMIIPQQANNNK 413 788999776788899986666666665554 PP >> Beta-prop_BBS7 BBS7 beta-propeller # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.1 6.6e-06 0.056 65 128 .. 305 368 .. 297 376 .. 0.88 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 6.6e-06 Beta-prop_BBS7 65 asgsevkGytkkGKqflsFdtnltesiksmyvsgsdLlvcgkyvynhykdckdknyyl.sgdkin 128 a g + kGy kG f + d +l+e ++ m v g+dL + v+ ++ k +++++ +d+in FUN_002143-T1 305 AYGVTLKGYAVKGGRF-TLDKTLAEMLNVMNVAGTDLGNGVHFVFRDNENIKRTDTFTyNNDEIN 368 667889*******998.79*******************************999998851567776 PP >> DUF1611_N Domain of unknown function (DUF1611_N) Rossmann-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.1 0.0034 29 21 67 .. 60 108 .. 39 112 .. 0.72 2 ? 5.9 0.0 0.0028 24 34 80 .. 308 356 .. 279 359 .. 0.77 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.0034 DUF1611_N 21 vssleealaagaealviGiapegg..klpeswreavveAleaGldvvsG 67 ss +e l+ ++ + + ++ g kl ++w++ +++A + G v++G FUN_002143-T1 60 ASSQAEPLNTHPNEIAVSMEVVGHvpKLMAQWVKFLKRASNSGTVVITG 108 33344448888889999999988744689******************99 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0028 DUF1611_N 34 alviGiapeggklp..eswreavveAleaGldvvsGlHefLsddpelaa 80 + + G a +gg+++ +++ e + aG d+ +G H +d++++++ FUN_002143-T1 308 VTLKGYAVKGGRFTldKTLAEMLNVMNVAGTDLGNGVHFVFRDNENIKR 356 4566999****98764666777777778****************99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (463 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 867 (0.0339401); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 4601.01 // Query: FUN_002144-T1 [L=143] Description: FUN_002144 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.051 13.8 0.1 0.15 12.3 0.0 1.8 2 rva_4 Integrase core domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 0.2 5.2e+03 14 26 .. 114 126 .. 107 128 .. 0.72 2 ? 12.3 0.0 5.7e-06 0.15 2 14 .. 131 143 .] 130 143 .] 0.95 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 0.2 rva_4 14 dgnmklirWrlvv 26 d irW +v+ FUN_002144-T1 114 DPGNSRIRWAVVI 126 5555569999998 PP == domain 2 score: 12.3 bits; conditional E-value: 5.7e-06 rva_4 2 ykvatPnslWhid 14 y+va PnslWhid FUN_002144-T1 131 YSVAGPNSLWHID 143 9***********8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (143 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 495 (0.0193776); expected 510.9 (0.02) Passed bias filter: 447 (0.0174985); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1456.07 // Query: FUN_002162-T1 [L=115] Description: FUN_002162 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 968 (0.0378939); expected 510.9 (0.02) Passed bias filter: 629 (0.0246232); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1189.79 // Query: FUN_002163-T1 [L=68] Description: FUN_002163 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.8 0.0 0.36 11.5 0.0 1.8 1 DUF7692 Domain of unknown function (DUF7692) Domain annotation for each model (and alignments): >> DUF7692 Domain of unknown function (DUF7692) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 1.4e-05 0.36 25 43 .. 48 66 .. 24 67 .. 0.78 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 1.4e-05 DUF7692 25 cNktkAvvfAcedvprlve 43 c ++A+++Ac+ ++rl + FUN_002163-T1 48 CPWSRAIMQACHETRRLKQ 66 6679***********9965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (68 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 494 (0.0193384); expected 510.9 (0.02) Passed bias filter: 404 (0.0158152); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.38 # Mc/sec: 713.77 // Query: FUN_002164-T1 [L=99] Description: FUN_002164 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.021 15.9 2.5 0.025 15.7 2.5 1.2 1 YabA Initiation control protein YabA 0.023 15.3 2.3 0.032 14.8 2.3 1.2 1 XRCC4_CC XRCC4 coiled-coil 0.031 13.7 0.6 0.037 13.4 0.6 1.0 1 Ntox11 Novel toxin 11 Domain annotation for each model (and alignments): >> YabA Initiation control protein YabA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 2.5 2.9e-06 0.025 30 68 .. 19 57 .. 1 64 [. 0.73 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2.9e-06 YabA 30 elaelleenaeLeiEnekLrerlkkeeekekekkkelse 68 l+e+++ n++L EnekLr++ ++++++++e +++++ FUN_002164-T1 19 LLEEVIQSNRDLAAENEKLRQEHEETSKHQAEALNRIEQ 57 57899*****************97777776666555544 PP >> XRCC4_CC XRCC4 coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 2.3 3.8e-06 0.032 7 47 .. 8 49 .. 4 62 .. 0.76 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 3.8e-06 XRCC4_CC 7 irelis.ycLdqiaelqaknehLqkEnerLlrdwsdvqerle 47 ir ++s c+ + e ++n+ L Ene+L++++++ +++ FUN_002164-T1 8 IRSVMSeDCVVLLEEVIQSNRDLAAENEKLRQEHEETSKHQA 49 67777624888889999*****************99876544 PP >> Ntox11 Novel toxin 11 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.6 4.4e-06 0.037 49 108 .. 28 89 .. 22 94 .. 0.85 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 4.4e-06 Ntox11 49 sdllakdakktrdamqgselkae...rieavrseGsdprgrlrqgrhpgprprrgvilrlPks 108 dl+a + k ++ + s+++ae rie eG g lr+ +pg r r ++ +P++ FUN_002164-T1 28 RDLAAENEKLRQEHEETSKHQAEalnRIEQRLKEGET-PGILRRRARPGARAREARNIAVPAA 89 6999999999999999999999744467777788888.799********************94 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2566 (0.10045); expected 510.9 (0.02) Passed bias filter: 1515 (0.0593071); expected 510.9 (0.02) Passed Vit filter: 139 (0.00544138); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.39 # Mc/sec: 1015.83 // Query: FUN_002165-T1 [L=142] Description: FUN_002165 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.046 14.7 1.8 9.6 7.2 0.2 2.6 2 DUF1096 Protein of unknown function (DUF1096) Domain annotation for each model (and alignments): >> DUF1096 Protein of unknown function (DUF1096) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.2 0.00038 9.6 10 22 .. 32 44 .. 19 49 .. 0.80 2 ? 6.3 0.1 0.00072 18 8 22 .. 56 70 .. 52 80 .. 0.86 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.00038 DUF1096 10 sCdCapkeqpsCs 22 dC+ + q+sCs FUN_002165-T1 32 ESDCTEEDQSSCS 44 469*********8 PP == domain 2 score: 6.3 bits; conditional E-value: 0.00072 DUF1096 8 RQsCdCapkeqpsCs 22 R dC+ + q sC+ FUN_002165-T1 56 REESDCTEEDQTSCG 70 7778**********7 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1902 (0.0744568); expected 510.9 (0.02) Passed bias filter: 667 (0.0261108); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1464.23 // Query: FUN_002166-T1 [L=281] Description: FUN_002166 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.036 14.7 1.1 0.063 13.9 1.1 1.4 1 CEP104_ZnF Centrosomal protein CEP104, ZnF 2.4 8.1 5.6 3.6 7.6 5.6 1.2 1 SURF2 Surfeit locus protein 2 (SURF2) Domain annotation for each model (and alignments): >> CEP104_ZnF Centrosomal protein CEP104, ZnF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 1.1 5e-06 0.063 53 102 .. 6 55 .. 1 76 [. 0.71 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 5e-06 CEP104_ZnF 53 kkekvkqCerckeavkkeelekhvkkkkckaakeee.easrCplCheevek 102 +++ + C +c ++v+++++++h + k+c+a++ +e +s+ +lC+++ e+ FUN_002166-T1 6 ESKGYVYCAHCDNVVSRSTFRRHER-KRCSATSGSEiGQSQVTLCSSDSET 55 5567788888888888888888864.6676655443156777888777654 PP >> SURF2 Surfeit locus protein 2 (SURF2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 5.6 0.00028 3.6 136 234 .. 26 126 .. 10 131 .. 0.70 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.00028 SURF2 136 ekkkkkkegewepass.deeasd.sddsmsDlypdelfteksv.geeededdkesdfetdeeeekakesdekgeeekeeeevekskrkkrkkkqig 228 +++++k+ + +++ ++++ s+ds++ + p ++ +++ ++ ++++++ d d+e+ + + +++++ +++ + e ++ +r+krk++ + FUN_002166-T1 26 RRHERKRCSATSGSEIgQSQVTLcSSDSETSSSPVDEECVPEEpASVVQGETSG-DAILDNEQSMDEAASDETWHSETDSENDSVNRAKRKSVGDE 120 455555555566666445555557999999999977666665505555555555.888899988888888888666666677789999**999877 PP SURF2 229 ssskkf 234 s++ + FUN_002166-T1 121 STTSES 126 777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (281 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1033 (0.0404384); expected 510.9 (0.02) Passed bias filter: 555 (0.0217264); expected 510.9 (0.02) Passed Vit filter: 57 (0.00223136); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 2686.66 // Query: FUN_002167-T1 [L=524] Description: FUN_002167 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (524 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1369 (0.0535917); expected 510.9 (0.02) Passed bias filter: 832 (0.03257); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.36u 0.42s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 4987.27 // Query: FUN_002169-T1 [L=272] Description: FUN_002169 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00013 23.0 8.3 0.00013 23.0 8.3 4.1 4 zf-TRAF TRAF-type zinc finger 0.002 18.4 0.1 0.002 18.4 0.1 4.5 5 zf_C2HC_14 C2HC Zing finger domain 0.0025 18.1 14.0 0.0025 18.1 14.0 4.0 4 zf-C3HC4 Zinc finger, C3HC4 type (RING finger) Domain annotation for each model (and alignments): >> zf-TRAF TRAF-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 3.5 3 2.6e+04 41 55 .. 38 53 .. 31 64 .. 0.56 2 ! 9.0 8.7 0.00038 3.2 11 60 .] 84 127 .. 79 127 .. 0.87 3 ! 23.0 8.3 1.6e-08 0.00013 1 58 [. 127 177 .. 125 179 .. 0.89 4 ! 11.5 0.9 6.1e-05 0.52 1 32 [. 179 210 .. 179 214 .. 0.92 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 3 zf-TRAF 41 CkfkevG.Ckekvkre 55 C + + G C+e+++++ FUN_002169-T1 38 CGHAVCGhCAERLEEN 53 4444333366665554 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00038 zf-TRAF 11 pCpnecckkkilRedlkdHlekdCkkaevkCkfkevGCkekvkrealqkH 60 +C ++c + ++ ++++H+ C++ e+kC C++ vkr++ H FUN_002169-T1 84 TC-KGCN-NDVPLSEIQQHVTVLCQEMEEKCAQ----CQNCVKRSETHAH 127 78.5555.66***********************....*999999998888 PP == domain 3 score: 23.0 bits; conditional E-value: 1.6e-08 zf-TRAF 1 HletCpfapvpCpnecckkkilRedlkdHlekdCkkaevkCkfkevGCkekvkrealq 58 H++ Cp+a+++C +c+ +i R+d + H + +Ck ev+C GC+e +kr + FUN_002169-T1 127 HNQICPKANITC--DCG-IIIWRQDEESHRQ-YCKLKEVQCCL---GCEESIKRYLVP 177 8999********..455.88*********99.**********9...*****9987655 PP == domain 4 score: 11.5 bits; conditional E-value: 6.1e-05 zf-TRAF 1 HletCpfapvpCpnecckkkilRedlkdHlek 32 H +C+++ +Cp + c + Red++ Hl++ FUN_002169-T1 179 HCMSCSKVVEQCPIGGCGQYHRREDMPTHLAD 210 7789*************************985 PP >> zf_C2HC_14 C2HC Zing finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -4.1 1.0 2.6 2.2e+04 7 15 .. 35 43 .. 34 43 .. 0.85 2 ? -1.6 0.2 0.43 3.7e+03 4 12 .. 55 63 .. 52 64 .. 0.75 3 ! 18.4 0.1 2.4e-07 0.002 4 23 .. 82 101 .. 80 105 .. 0.92 4 ? 0.9 5.3 0.068 5.8e+02 3 28 .. 108 133 .. 106 134 .. 0.92 5 ? 2.8 8.2 0.018 1.5e+02 5 32 .. 162 189 .. 159 190 .. 0.91 Alignments for each domain: == domain 1 score: -4.1 bits; conditional E-value: 2.6 zf_C2HC_14 7 CkgCekkVc 15 C+ C Vc FUN_002169-T1 35 CNPCGHAVC 43 899999888 PP == domain 2 score: -1.6 bits; conditional E-value: 0.43 zf_C2HC_14 4 egnCkgCek 12 + nC+ C++ FUN_002169-T1 55 SLNCHMCRE 63 569*99985 PP == domain 3 score: 18.4 bits; conditional E-value: 2.4e-07 zf_C2HC_14 4 egnCkgCekkVcLSkMRaHl 23 +++CkgC++ V LS++ +H+ FUN_002169-T1 82 KATCKGCNNDVPLSEIQQHV 101 799****************8 PP == domain 4 score: 0.9 bits; conditional E-value: 0.068 zf_C2HC_14 3 tegnCkgCekkVcLSkMRaHlatCeK 28 e +C C++ V+ S+ aH + C K FUN_002169-T1 108 MEEKCAQCQNCVKRSETHAHNQICPK 133 6889********************98 PP == domain 5 score: 2.8 bits; conditional E-value: 0.018 zf_C2HC_14 5 gnCkgCekkVcLSkMRaHlatCeKYqey 32 + C gCe+ ++ + +H +C+K++e+ FUN_002169-T1 162 QCCLGCEESIKRYLVPSHCMSCSKVVEQ 189 77***********************986 PP >> zf-C3HC4 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 14.0 3e-07 0.0025 1 40 [] 22 61 .. 22 61 .. 0.99 2 ? -4.2 0.2 2.7 2.3e+04 22 25 .. 85 88 .. 83 91 .. 0.60 3 ? -0.7 5.3 0.23 1.9e+03 22 38 .. 115 132 .. 94 133 .. 0.80 4 ? -5.2 5.5 3 2.6e+04 22 40 .] 164 183 .. 160 192 .. 0.57 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 3e-07 zf-C3HC4 1 CpiCleelkepvtllpCgHsfCssCiksllesnnvkCplC 40 C iC l +p++ pCgH+ C C + l e+ + +C++C FUN_002169-T1 22 CEICAYPLVNPKICNPCGHAVCGHCAERLEENASLNCHMC 61 *******************************999****** PP == domain 2 score: -4.2 bits; conditional E-value: 2.7 zf-C3HC4 22 CssC 25 C+ C FUN_002169-T1 85 CKGC 88 4444 PP == domain 3 score: -0.7 bits; conditional E-value: 0.23 zf-C3HC4 22 CssCiksllesnnvk.Cp 38 C++C+k + +++ Cp FUN_002169-T1 115 CQNCVKRSETHAHNQiCP 132 999999998876666698 PP == domain 4 score: -5.2 bits; conditional E-value: 3 zf-C3HC4 22 CssCikslle.snnvkCplC 40 C C +s+ + ++ C+ C FUN_002169-T1 164 CLGCEESIKRyLVPSHCMSC 183 44444444443223445555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (272 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1524 (0.0596594); expected 510.9 (0.02) Passed bias filter: 447 (0.0174985); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2661.54 // Query: FUN_002170-T1 [L=139] Description: FUN_002170 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (139 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 707 (0.0276766); expected 510.9 (0.02) Passed bias filter: 482 (0.0188687); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1400.76 // Query: FUN_002175-T1 [L=109] Description: FUN_002175 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.032 15.1 0.0 0.049 14.5 0.0 1.3 1 DUF6582 Family of unknown function (DUF6582) Domain annotation for each model (and alignments): >> DUF6582 Family of unknown function (DUF6582) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 1.9e-06 0.049 13 49 .. 17 51 .. 9 61 .. 0.82 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.9e-06 DUF6582 13 PeeGereyGdveFAdpknkKyPidtaeHvRaAwsyin 49 P+ ++G++ Ad+ K P+ +a+H+R+ +syi FUN_002175-T1 17 PSTVIIDFGKSVLADK--AKVPMAKAKHIRSNFSYIA 51 5666668899999985..69***************96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (109 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 337 (0.0131924); expected 510.9 (0.02) Passed bias filter: 318 (0.0124486); expected 510.9 (0.02) Passed Vit filter: 20 (0.000782932); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.41 # Mc/sec: 1081.99 // Query: FUN_002176-T1 [L=121] Description: FUN_002176 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 892 (0.0349188); expected 510.9 (0.02) Passed bias filter: 435 (0.0170288); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.38s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1219.23 // Query: FUN_002177-T1 [L=149] Description: FUN_002177 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (149 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 446 (0.0174594); expected 510.9 (0.02) Passed bias filter: 408 (0.0159718); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1490.16 // Query: FUN_002178-T1 [L=103] Description: FUN_002178 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.23 12.0 0.0 0.45 11.1 0.0 1.5 1 WHD_F93 F-93, winged-helix domain Domain annotation for each model (and alignments): >> WHD_F93 F-93, winged-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 1.8e-05 0.45 7 55 .. 39 83 .. 35 87 .. 0.84 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 1.8e-05 WHD_F93 7 ydnegvtvyeilkklneevelaqstfydvkeeLiqeGlvaeReeegkkr 55 y+neg + y+ +a++ f ++++ + ++G+ + R++++++r FUN_002178-T1 39 YNNEGPPLYDPNEME----AFAPALFTQILKSILNNGMSKDRQDKQRRR 83 677777777655555....799*********************999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1129 (0.0441965); expected 510.9 (0.02) Passed bias filter: 855 (0.0334703); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.41s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1020.72 // Query: FUN_002179-T1 [L=177] Description: FUN_002179 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.037 14.2 0.1 0.055 13.6 0.1 1.2 1 Herpes_teg_N Herpesvirus tegument protein, N-terminal conser Domain annotation for each model (and alignments): >> Herpes_teg_N Herpesvirus tegument protein, N-terminal conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 2.2e-06 0.055 134 173 .. 129 166 .. 103 174 .. 0.82 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.2e-06 Herpes_teg_N 134 YiliivnslamaivikdktlylFDpHglpegnstaavivt 173 + i++ + +a + +++++l D+H+ +++s+a++ + FUN_002179-T1 129 TSVFIIDQKTVAFIPMGQHVLLLDSHC--HAQSGAHIAMA 166 46889**********************..66679998765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (177 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 369 (0.0144451); expected 510.9 (0.02) Passed bias filter: 325 (0.0127226); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.41s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1766.48 // Query: FUN_002185-T1 [L=188] Description: FUN_002185 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0065 17.3 23.4 2.6 9.0 0.8 5.2 6 DUF2554 Protein of unknown function (DUF2554) ------ inclusion threshold ------ 0.18 11.9 10.7 8.1 6.5 0.1 3.9 3 DNA_ligase_A_M ATP dependent DNA ligase domain 0.25 11.3 9.6 3.6 7.5 1.1 3.4 4 DUF1444 Protein of unknown function (DUF1444) 0.43 11.0 6.8 5.9 7.3 0.3 2.6 3 DAP_B D-aminopeptidase, domain B 1 10.6 3.5 59 4.9 0.1 3.7 5 Chordopox_G3 Chordopoxvirus G3 protein 2.9 8.6 7.5 2 9.1 3.6 2.4 3 DUF7969 Domain of unknown function (DUF7969) 3 8.5 5.6 20 5.9 0.5 3.3 3 SdrD_B SdrD B-like domain Domain annotation for each model (and alignments): >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.7 1.2 0.0078 29 39 67 .. 3 31 .. 1 35 [. 0.87 2 ! 5.8 0.2 0.0069 25 38 64 .. 24 50 .. 19 58 .. 0.85 3 ! 5.3 0.1 0.01 36 23 64 .. 50 91 .. 44 96 .. 0.84 4 ! 9.0 0.8 0.00071 2.6 38 64 .. 98 124 .. 92 129 .. 0.86 5 ? 4.6 0.0 0.017 63 38 63 .. 120 145 .. 115 153 .. 0.85 6 ! 8.8 1.8 0.00085 3.1 38 65 .. 153 180 .. 142 187 .. 0.84 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0078 DUF2554 39 lrheadsdelravaeesaeGlrehfywqk 67 + he sd +r e+ ++Gl h+ + FUN_002185-T1 3 VHHEKRSDWVRDDHEKKSDGLTVHHEKKS 31 67**********************98654 PP == domain 2 score: 5.8 bits; conditional E-value: 0.0069 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he sd +r e+ + G+r ++ FUN_002185-T1 24 TVHHEKKSDRVRVDHEKKSHGVRVDHK 50 578*******************98775 PP == domain 3 score: 5.3 bits; conditional E-value: 0.01 DUF2554 23 kqkdhefvwvktvdhqlrheadsdelravaeesaeGlrehfy 64 k+k f k+ + ++ +e s+ +r v e+ + G+r + FUN_002185-T1 50 KEKSEGFTIRKSKGVRVHYEKKSNGVRVVHEKKSAGVRVNHE 91 556677888889999999*******************98775 PP == domain 4 score: 9.0 bits; conditional E-value: 0.00071 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he sde+r e+ +G+r ++ FUN_002185-T1 98 GVHHEKKSDEVRVHHEKKRDGIRVYHE 124 578********************9886 PP == domain 5 score: 4.6 bits; conditional E-value: 0.017 DUF2554 38 qlrheadsdelravaeesaeGlrehf 63 ++ he sd +r e+ ++G++ + FUN_002185-T1 120 RVYHERKSDGVRVNNEKKSDGVKVDH 145 577******************98766 PP == domain 6 score: 8.8 bits; conditional E-value: 0.00085 DUF2554 38 qlrheadsdelravaeesaeGlrehfyw 65 + he sd +r e ++G+r h+ FUN_002185-T1 153 TVHHEKKSDGVRLQHERNSDGVRVHHEK 180 578**********************963 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.2 0.015 54 14 43 .. 58 87 .. 49 90 .. 0.82 2 ? 6.2 0.7 0.0028 10 18 43 .. 117 142 .. 97 145 .. 0.74 3 ? 6.5 0.1 0.0022 8.1 20 44 .. 152 176 .. 144 178 .. 0.84 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.015 DNA_ligase_A_M 14 lkklegkafivEiKyDGeRaqvhkegdevk 43 ++k +g +++E K +G+R+ +k++ v+ FUN_002185-T1 58 IRKSKGVRVHYEKKSNGVRVVHEKKSAGVR 87 6777888899*********98888777665 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0028 DNA_ligase_A_M 18 egkafivEiKyDGeRaqvhkegdevk 43 +g ++ E K DG+R+ +k++d vk FUN_002185-T1 117 DGIRVYHERKSDGVRVNNEKKSDGVK 142 35567788888888888888877776 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0022 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegdevkl 44 +++ E K DG+R+q ++++d v++ FUN_002185-T1 152 VTVHHEKKSDGVRLQHERNSDGVRV 176 56778*************9999875 PP >> DUF1444 Protein of unknown function (DUF1444) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.5 1.1 0.001 3.6 19 77 .. 23 81 .. 12 91 .. 0.60 2 ? 4.1 0.9 0.011 40 17 62 .. 62 107 .. 50 119 .. 0.73 3 ? 4.7 1.3 0.0071 26 15 47 .. 104 136 .. 87 163 .. 0.62 4 ? 2.2 0.1 0.042 1.5e+02 13 44 .. 146 177 .. 136 182 .. 0.79 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.001 DUF1444 19 vtlkfdreedtlriedkktkkgvtiklkeliakyeekkekaidevveyveealkalkee 77 t+++++++d++r+ ++k+ +gv ++ ke + +k k ++ e+ ++++++++e+ FUN_002185-T1 23 LTVHHEKKSDRVRVDHEKKSHGVRVDHKEKSEGFTIRKSKGVRVHYEKKSNGVRVVHEK 81 55666666666666666666666666666666666666665555555555555555544 PP == domain 2 score: 4.1 bits; conditional E-value: 0.011 DUF1444 17 eevtlkfdreedtlriedkktkkgvtiklkeliakyeekkekaide 62 + v+++++++++ +r++++k+ gv ++ ++ + ++ek de FUN_002185-T1 62 KGVRVHYEKKSNGVRVVHEKKSAGVRVNHEKKSDGVGVHHEKKSDE 107 6678999999999999999999999887766555555444444444 PP == domain 3 score: 4.7 bits; conditional E-value: 0.0071 DUF1444 15 keeevtlkfdreedtlriedkktkkgvtiklke 47 k++ev++++++++d +r+ ++++ gv ++ ++ FUN_002185-T1 104 KSDEVRVHHEKKRDGIRVYHERKSDGVRVNNEK 136 445556666666666666666666666555443 PP == domain 4 score: 2.2 bits; conditional E-value: 0.042 DUF1444 13 klkeeevtlkfdreedtlriedkktkkgvtik 44 + +++ vt+++++++d +r++++++ gv ++ FUN_002185-T1 146 EKRSDGVTVHHEKKSDGVRLQHERNSDGVRVH 177 45567788999999999999999999998875 PP >> DAP_B D-aminopeptidase, domain B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 0.33 1.2e+03 51 79 .. 19 46 .. 4 62 .. 0.46 2 ? 6.8 0.8 0.0023 8.5 26 81 .. 60 114 .. 35 129 .. 0.68 3 ? 7.3 0.3 0.0016 5.9 21 72 .. 130 182 .. 117 186 .. 0.81 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 0.33 DAP_B 51 esksvvaeidgdtlkierekenrtlkarr 79 +s +++++ ++++ ++++ +e+++ + r FUN_002185-T1 19 KSDGLTVHHEKKSDRVRVDHEKKS-HGVR 46 333333333333333333222221.2222 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0023 DAP_B 26 aekgkvkiryaksaeklklvseneaesksvvaeidgdtlkierekenrtlkarrvk 81 ++kg v ++y+k+++ +++v+e+++ +v e + d + ++ ek +++++ k FUN_002185-T1 60 KSKG-VRVHYEKKSNGVRVVHEKKSAGVRVNHEKKSDGVGVHHEKKSDEVRVHHEK 114 3344.777788888888888877777777777777777777776666665555444 PP == domain 3 score: 7.3 bits; conditional E-value: 0.0016 DAP_B 21 vtvekaek.gkvkiryaksaeklklvseneaesksvvaeidgdtlkiereken 72 v+v++++k vk+ ++k ++ +++ +e+++ ++ e++ d ++++ eke FUN_002185-T1 130 VRVNNEKKsDGVKVDHEKRSDGVTVHHEKKSDGVRLQHERNSDGVRVHHEKER 182 455444443449**********************************9999885 PP >> Chordopox_G3 Chordopoxvirus G3 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.016 59 60 95 .. 27 62 .. 6 66 .. 0.67 2 ? 2.4 0.0 0.098 3.6e+02 65 94 .. 62 91 .. 57 97 .. 0.84 3 ? -0.4 0.0 0.75 2.7e+03 67 92 .. 97 122 .. 88 131 .. 0.66 4 ? 0.3 0.1 0.43 1.6e+03 64 94 .. 105 135 .. 100 148 .. 0.66 5 ? 1.2 0.0 0.23 8.4e+02 63 95 .. 137 169 .. 130 176 .. 0.80 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.016 Chordopox_G3 60 ekvisdqviltydartgtvtvavkgkkyifrldded 95 + sd+v++ +++++ v+v++k+k+ f + + + FUN_002185-T1 27 HEKKSDRVRVDHEKKSHGVRVDHKEKSEGFTIRKSK 62 444567777777777777777777777777776665 PP == domain 2 score: 2.4 bits; conditional E-value: 0.098 Chordopox_G3 65 dqviltydartgtvtvavkgkkyifrldde 94 + v++ y+++++ v+v +++k+ r+++e FUN_002185-T1 62 KGVRVHYEKKSNGVRVVHEKKSAGVRVNHE 91 568999************999988888865 PP == domain 3 score: -0.4 bits; conditional E-value: 0.75 Chordopox_G3 67 viltydartgtvtvavkgkkyifrld 92 v + +++++ v+v++++k+ r++ FUN_002185-T1 97 VGVHHEKKSDEVRVHHEKKRDGIRVY 122 55666777777777777777655554 PP == domain 4 score: 0.3 bits; conditional E-value: 0.43 Chordopox_G3 64 sdqviltydartgtvtvavkgkkyifrldde 94 sd+v++ +++++ ++v +++k+ r+++e FUN_002185-T1 105 SDEVRVHHEKKRDGIRVYHERKSDGVRVNNE 135 5566666666666666666666666665544 PP == domain 5 score: 1.2 bits; conditional E-value: 0.23 Chordopox_G3 63 isdqviltydartgtvtvavkgkkyifrldded 95 sd v++ ++r++ vtv++++k+ rl++e+ FUN_002185-T1 137 KSDGVKVDHEKRSDGVTVHHEKKSDGVRLQHER 169 577888999999999999999998887777655 PP >> DUF7969 Domain of unknown function (DUF7969) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 0.38 1.4e+03 109 130 .. 21 42 .. 15 64 .. 0.59 2 ? 9.1 3.6 0.00056 2 45 131 .. 67 150 .. 54 162 .. 0.76 3 ? -1.7 0.0 1.2 4.4e+03 50 62 .. 159 171 .. 153 185 .. 0.52 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.38 DUF7969 109 dGrevdpraeselveidpdrps 130 dG v + +s++v++d ++ s FUN_002185-T1 21 DGLTVHHEKKSDRVRVDHEKKS 42 5555555666666666654332 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00056 DUF7969 45 efedddadGvrlvCGesd.eeeaeaeeakegveatedaseaddveeeekasgCGeefylsfvryedGrevdpraeselveidpdrpsg 131 ++e+ +++Gvr+v + + ++++++e++++gv +++ +++d+v +++++ G ++y r dG v+ + +s+ v++d ++ s FUN_002185-T1 67 HYEK-KSNGVRVVHEKKSaGVRVNHEKKSDGVGVHHE-KKSDEVRVHHEKKRDGIRVYH--ERKSDGVRVNNEKKSDGVKVDHEKRSD 150 5777.899*****987541567776666666666666.567777778888888999996..599*****************9976553 PP == domain 3 score: -1.7 bits; conditional E-value: 1.2 DUF7969 50 dadGvrlvCGesd 62 ++dGvrl + FUN_002185-T1 159 KSDGVRLQHERNS 171 5666666543322 PP >> SdrD_B SdrD B-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.35 1.3e+03 7 38 .. 3 34 .. 2 54 .. 0.70 2 ? 2.8 0.1 0.052 1.9e+02 4 36 .. 63 95 .. 60 109 .. 0.78 3 ? 5.9 0.5 0.0054 20 6 41 .. 120 155 .. 116 174 .. 0.70 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.35 SdrD_B 7 VweDanknGiqdagekGisgvtvtLkdesgev 38 V + + + + d+ ek +g tv+ +++s++v FUN_002185-T1 3 VHHEKRSDWVRDDHEKKSDGLTVHHEKKSDRV 34 55666667777888888888888877666655 PP == domain 2 score: 2.8 bits; conditional E-value: 0.052 SdrD_B 4 GdfVweDanknGiqdagekGisgvtvtLkdesg 36 G +V + nG+ ek +gv v+ +++s+ FUN_002185-T1 63 GVRVHYEKKSNGVRVVHEKKSAGVRVNHEKKSD 95 667889999999999999999999999866655 PP == domain 3 score: 5.9 bits; conditional E-value: 0.0054 SdrD_B 6 fVweDanknGiqdagekGisgvtvtLkdesgevvat 41 +V++ + +G+ ++ek +gv+v +++s+ v+ FUN_002185-T1 120 RVYHERKSDGVRVNNEKKSDGVKVDHEKRSDGVTVH 155 688888888888888888888888876555554433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 924 (0.0361715); expected 510.9 (0.02) Passed bias filter: 262 (0.0102564); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1835.89 // Query: FUN_002186-T1 [L=145] Description: FUN_002186 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00077 18.4 0.2 0.0044 15.9 0.2 1.7 1 Gp58 gp58-like protein ------ inclusion threshold ------ 0.028 16.0 0.6 44 5.7 0.0 3.7 4 Pheromone Fungal mating-type pheromone 0.077 13.9 15.2 1.1 10.2 2.9 3.7 4 DUF2554 Protein of unknown function (DUF2554) 0.093 12.8 2.0 0.15 12.1 0.9 1.7 2 DUF4843 Domain of unknown function (DUF4843) 0.37 10.9 6.5 0.57 10.3 0.2 2.8 3 DNA_ligase_A_M ATP dependent DNA ligase domain 0.67 10.3 10.1 2.6 8.4 1.3 2.1 2 DA_C Diels-Alderase, C-terminal domain 0.85 10.1 1.3 16 6.0 0.0 2.8 3 ComGE Competence system putative prepilin ComGE 1.8 9.0 5.5 42 4.7 0.9 4.0 3 DUF1869 Domain of unknown function (DUF1869) 2.8 9.3 12.3 2.5 9.5 4.1 2.3 2 DUF1764 Eukaryotic protein of unknown function (DUF17 2.9 7.5 10.4 7.6 6.2 0.5 3.2 4 DUF632 Protein of unknown function (DUF632) Domain annotation for each model (and alignments): >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.2 1.7e-06 0.0044 169 257 .. 21 109 .. 6 127 .. 0.76 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 1.7e-06 Gp58 169 syqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveleskisGlqst 257 +++ +Gl+a ++ + G++ + +g+ ++++ ++++ +ts+G t ye+k d++r ++ r + G++v+ e + G++ FUN_002186-T1 21 DHEKKSDGLRADHEKKRDGVRVHHERKSNGVRGDHEKKSNGVKVDHEKTSDGVTVYYEKKSDGVRLQHERKSDGVKVDHEKRSDGVKVH 109 56677788888888888888888888888888888888888888888999999999999999999999999999999888888887654 PP >> Pheromone Fungal mating-type pheromone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.99 2.5e+03 41 58 .. 22 39 .. 19 44 .. 0.80 2 ? 4.5 0.0 0.042 1.1e+02 41 60 .. 55 75 .. 51 77 .. 0.81 3 ? 5.7 0.0 0.017 44 41 58 .. 88 105 .. 85 110 .. 0.85 4 ? -0.0 0.0 1.1 2.8e+03 44 59 .. 113 129 .. 109 131 .. 0.76 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.99 Pheromone 41 sddevddvpvDaErrggg 58 ++ +d++ +D+E+ +g FUN_002186-T1 22 HEKKSDGLRADHEKKRDG 39 677889999****98777 PP == domain 2 score: 4.5 bits; conditional E-value: 0.042 Pheromone 41 sddevddvpvDaErrggg.ta 60 ++ +++v vD+E+ +g t+ FUN_002186-T1 55 HEKKSNGVKVDHEKTSDGvTV 75 677899***********9654 PP == domain 3 score: 5.7 bits; conditional E-value: 0.017 Pheromone 41 sddevddvpvDaErrggg 58 ++ +d+v vD+E+r +g FUN_002186-T1 88 HERKSDGVKVDHEKRSDG 105 67889***********99 PP == domain 4 score: -0.0 bits; conditional E-value: 1.1 Pheromone 44 evddvpvDaErrggg.t 59 + +v vD+E+ +g + FUN_002186-T1 113 KSHGVRVDHEKKSDGlG 129 567888****9999855 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 2.9 0.00044 1.1 40 64 .. 21 45 .. 3 55 .. 0.85 2 ? 3.4 0.1 0.056 1.4e+02 35 64 .. 60 89 .. 50 93 .. 0.82 3 ? 9.0 0.7 0.0011 2.7 34 64 .. 81 111 .. 65 117 .. 0.84 4 ? 4.4 2.0 0.029 73 37 65 .. 106 134 .. 99 143 .. 0.82 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00044 DUF2554 40 rheadsdelravaeesaeGlrehfy 64 he sd lra e+ +G+r h+ FUN_002186-T1 21 DHEKKSDGLRADHEKKRDGVRVHHE 45 4999999999999999999999997 PP == domain 2 score: 3.4 bits; conditional E-value: 0.056 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfy 64 + ++ he sd + e+ ++G+r + FUN_002186-T1 60 NGVKVDHEKTSDGVTVYYEKKSDGVRLQHE 89 566788999999999999999999997765 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0011 DUF2554 34 tvdhqlrheadsdelravaeesaeGlrehfy 64 + + +l+he sd ++ e+ ++G++ h+ FUN_002186-T1 81 SDGVRLQHERKSDGVKVDHEKRSDGVKVHHE 111 456789***********************97 PP == domain 4 score: 4.4 bits; conditional E-value: 0.029 DUF2554 37 hqlrheadsdelravaeesaeGlrehfyw 65 ++ he s +r e+ ++Gl h+ FUN_002186-T1 106 VKVHHEKKSHGVRVDHEKKSDGLGVHHEK 134 5788999****************999964 PP >> DUF4843 Domain of unknown function (DUF4843) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.9 5.9e-05 0.15 43 90 .. 50 98 .. 30 110 .. 0.77 2 ? -1.1 0.0 0.67 1.7e+03 47 70 .. 110 133 .. 102 138 .. 0.74 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 5.9e-05 DUF4843 43 Gevvdedre.yklevveekttaqegdhyealkeelelpadkvsvtlpvi 90 G + d++++ ++v++ekt+ +++ye+ + + l+ ++ s+ ++v FUN_002186-T1 50 GVRGDHEKKsNGVKVDHEKTSDGVTVYYEKKSDGVRLQHERKSDGVKVD 98 444455444157********************************99985 PP == domain 2 score: -1.1 bits; conditional E-value: 0.67 DUF4843 47 dedreyklevveekttaqegdhye 70 e + + v++ek + g+h+e FUN_002186-T1 110 HEKKSHGVRVDHEKKSDGLGVHHE 133 455667889999998888888875 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.6 0.035 90 24 39 .. 33 48 .. 16 63 .. 0.63 2 ? 10.3 0.2 0.00022 0.57 18 43 .. 71 96 .. 57 103 .. 0.86 3 ? -1.3 0.0 0.8 2.1e+03 20 40 .. 106 126 .. 97 130 .. 0.73 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.035 DNA_ligase_A_M 24 vEiKyDGeRaqvhkeg 39 E K DG+R+ ++++ FUN_002186-T1 33 HEKKRDGVRVHHERKS 48 3556666665555544 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00022 DNA_ligase_A_M 18 egkafivEiKyDGeRaqvhkegdevk 43 +g ++++E K DG+R+q ++++d vk FUN_002186-T1 71 DGVTVYYEKKSDGVRLQHERKSDGVK 96 456899**************999987 PP == domain 3 score: -1.3 bits; conditional E-value: 0.8 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegd 40 +++ E K G+R+ +k++d FUN_002186-T1 106 VKVHHEKKSHGVRVDHEKKSD 126 456678888899988777665 PP >> DA_C Diels-Alderase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 1.3 0.001 2.6 58 107 .. 21 70 .. 7 78 .. 0.80 2 ? 6.9 2.2 0.003 7.6 61 109 .. 79 127 .. 71 141 .. 0.77 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.001 DA_C 58 vvsktedsvvlekavdgekvakekvkegegvtGafrdkntGyvlefvspe 107 ++k++d + +++ +++ v ++++++++gv+G + k+ G ++ +++ FUN_002186-T1 21 DHEKKSDGLRADHEKKRDGVRVHHERKSNGVRGDHEKKSNGVKVDHEKTS 70 45666677777777777778899999****************99987765 PP == domain 2 score: 6.9 bits; conditional E-value: 0.003 DA_C 61 ktedsvvlekavdgekvakekvkegegvtGafrdkntGyvlefvspeeg 109 k++d v l+++++++ v+++++k+++gv+ + + k+ G +++ ++++g FUN_002186-T1 79 KKSDGVRLQHERKSDGVKVDHEKRSDGVKVHHEKKSHGVRVDHEKKSDG 127 6677888899999999999999999***************999885443 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.0062 16 55 77 .. 58 80 .. 52 86 .. 0.88 2 ? 1.3 0.1 0.18 4.6e+02 55 77 .. 91 113 .. 84 115 .. 0.84 3 ? -0.5 0.1 0.64 1.6e+03 57 76 .. 115 134 .. 106 136 .. 0.75 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0062 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv+v ++++++++v+ ++k FUN_002186-T1 58 KSNGVKVDHEKTSDGVTVYYEKK 80 56****************98876 PP == domain 2 score: 1.3 bits; conditional E-value: 0.18 ComGE 55 slNGvevtvkenqeelivlesgk 77 + Gv+v ++ ++++ v +++k FUN_002186-T1 91 KSDGVKVDHEKRSDGVKVHHEKK 113 5679999999*******999987 PP == domain 3 score: -0.5 bits; conditional E-value: 0.64 ComGE 57 NGvevtvkenqeelivlesg 76 Gv v ++++++l v +++ FUN_002186-T1 115 HGVRVDHEKKSDGLGVHHEK 134 58888888888888888876 PP >> DUF1869 Domain of unknown function (DUF1869) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.9 0.016 42 12 22 .. 58 68 .. 42 76 .. 0.84 2 ? 1.6 0.1 0.15 3.8e+02 12 22 .. 91 101 .. 80 106 .. 0.83 3 ? 1.4 0.0 0.17 4.4e+02 11 23 .. 112 124 .. 103 129 .. 0.81 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.016 DUF1869 12 knNGVSVDkdf 22 k+NGV VD++ FUN_002186-T1 58 KSNGVKVDHEK 68 88999999885 PP == domain 2 score: 1.6 bits; conditional E-value: 0.15 DUF1869 12 knNGVSVDkdf 22 k+ GV VD++ FUN_002186-T1 91 KSDGVKVDHEK 101 899*****986 PP == domain 3 score: 1.4 bits; conditional E-value: 0.17 DUF1869 11 NknNGVSVDkdfe 23 k+ GV VD++ + FUN_002186-T1 112 KKSHGVRVDHEKK 124 5899*****9865 PP >> DUF1764 Eukaryotic protein of unknown function (DUF1764) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 4.1 0.00097 2.5 16 76 .. 19 78 .. 8 80 .. 0.53 2 ? 4.1 2.1 0.045 1.1e+02 32 78 .. 91 135 .. 77 137 .. 0.46 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00097 DUF1764 16 sekkkkkkekkkeekeekekkkkkkkkkkkkkkkeeeekfedskekkkrkktedGlpvYte 76 ++++kk++ ++++e+k+ + ++++k++ + ++ek +++ k ++kt+dG++vY e FUN_002186-T1 19 RDDHEKKSDGLRADHEKKRDGVRVHHERKSNGVRGDHEK-KSNGVKVDHEKTSDGVTVYYE 78 344444444444443333333344444444433333333.333358999**********87 PP == domain 2 score: 4.1 bits; conditional E-value: 0.045 DUF1764 32 ekekkkkkkkkkkkkkkkeeeekfedsk.ekkkrkktedGlpvYteee 78 +++ k +++k+++ k ++e+k + + ++k++dGl v++e+e FUN_002186-T1 91 KSDGVKVDHEKRSDGVKVHHEKKS---HgVRVDHEKKSDGLGVHHEKE 135 222222222222222222222222...234567788899999998876 PP >> DUF632 Protein of unknown function (DUF632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.3 0.0088 23 108 142 .. 13 47 .. 7 50 .. 0.87 2 ? 6.1 0.3 0.0031 8 108 142 .. 35 69 .. 32 73 .. 0.93 3 ? 6.2 0.5 0.003 7.6 108 142 .. 68 102 .. 65 110 .. 0.87 4 ? 0.1 0.1 0.21 5.2e+02 108 129 .. 112 133 .. 104 141 .. 0.61 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.0088 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K ++ +r ++ekk+ Lr ek+ + ++ r+ FUN_002186-T1 13 KRSDWVRDDHEKKSDGLRADHEKKRDGVRVHHERK 47 778889999*********99999999999988876 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0031 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ +r+ +e+k++ r ek+ + k+d ++ FUN_002186-T1 35 KKRDGVRVHHERKSNGVRGDHEKKSNGVKVDHEKT 69 8899***************************9886 PP == domain 3 score: 6.2 bits; conditional E-value: 0.003 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ + + yekk+ r + e++ + k+d + FUN_002186-T1 68 KTSDGVTVYYEKKSDGVRLQHERKSDGVKVDHEKR 102 77888999999999999999999999999998775 PP == domain 4 score: 0.1 bits; conditional E-value: 0.21 DUF632 108 KaeeklrieyekkckqLrklee 129 K++ +r+++ekk+ L + e FUN_002186-T1 112 KKSHGVRVDHEKKSDGLGVHHE 133 5556677777777766654444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (145 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 776 (0.0303778); expected 510.9 (0.02) Passed bias filter: 287 (0.0112351); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 13 (0.000508906); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1472.66 // Query: FUN_002187-T1 [L=131] Description: FUN_002187 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0013 19.6 10.1 1.3 10.0 2.2 3.7 4 DUF2554 Protein of unknown function (DUF2554) ------ inclusion threshold ------ 0.059 13.5 10.7 4.2 7.5 0.1 4.0 3 DNA_ligase_A_M ATP dependent DNA ligase domain 0.06 12.1 0.2 15 4.2 0.0 2.2 2 Gp58 gp58-like protein 0.26 11.7 2.5 7.4 7.0 0.3 2.0 2 DAP_B D-aminopeptidase, domain B 1.7 9.2 13.2 13 6.3 0.3 5.4 7 Beta-APP Beta-amyloid peptide (beta-APP) 5.9 7.6 13.7 2.2e+02 2.5 0.0 7.0 9 Tower Tower 9.4 6.7 5.9 1.9e+02 2.5 0.1 3.7 4 ComGE Competence system putative prepilin ComGE Domain annotation for each model (and alignments): >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.23 8.2e+02 38 58 .. 8 28 .. 2 30 .. 0.52 2 ! 8.3 0.3 0.0011 4.2 33 64 .. 25 56 .. 12 63 .. 0.85 3 ? 4.5 0.1 0.018 66 38 64 .. 63 89 .. 57 93 .. 0.82 4 ! 10.0 2.2 0.00035 1.3 38 67 .. 96 128 .. 86 130 .. 0.81 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.23 DUF2554 38 qlrheadsdelravaeesaeG 58 ++ +e s+ +r v e+ + G FUN_002187-T1 8 RVHYEKKSNGVRVVHEKKSAG 28 344555566666666655555 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0011 DUF2554 33 ktvdhqlrheadsdelravaeesaeGlrehfy 64 k+++ ++ he sd + e+ ++G+r h+ FUN_002187-T1 25 KSAGVRVNHEKKSDGVGVNHEKKSDGVRVHHG 56 45677899**********************96 PP == domain 3 score: 4.5 bits; conditional E-value: 0.018 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 ++ he sd +r ++ ++G+r + FUN_002187-T1 63 RVCHERKSDGVRVNHKKKSDGVRVDHE 89 678999******999999999997764 PP == domain 4 score: 10.0 bits; conditional E-value: 0.00035 DUF2554 38 qlrheadsdelravaeesaeGlrehfy...wqk 67 + he sd +r e ++G+r h+ w k FUN_002187-T1 96 TVHHEKKSDGVRLQHERNSDGVRVHHEkerWVK 128 578**********************96222555 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.023 82 20 41 .. 7 28 .. 1 36 [. 0.67 2 ? 4.1 3.0 0.012 45 21 42 .. 63 84 .. 30 87 .. 0.68 3 ? 7.5 0.1 0.0012 4.2 20 44 .. 95 119 .. 86 124 .. 0.85 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.023 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegde 41 +++E K +G+R+ +k++ FUN_002187-T1 7 VRVHYEKKSNGVRVVHEKKSAG 28 4556777888888766666555 PP == domain 2 score: 4.1 bits; conditional E-value: 0.012 DNA_ligase_A_M 21 afivEiKyDGeRaqvhkegdev 42 + E K DG+R+ +k++d v FUN_002187-T1 63 RVCHERKSDGVRVNHKKKSDGV 84 3445666666666666666655 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0012 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegdevkl 44 +++ E K DG+R+q ++++d v++ FUN_002187-T1 95 VTVHHEKKSDGVRLQHERNSDGVRV 119 56778*************9999875 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.0043 16 229 258 .. 4 33 .. 2 54 .. 0.63 2 ? 4.2 0.0 0.0041 15 226 257 .. 67 98 .. 49 125 .. 0.52 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0043 Gp58 229 LddlraeftrsnqGmrveleskisGlqstq 258 d++r ++ + + G+rv+ e k +G++ FUN_002187-T1 4 SDGVRVHYEKKSNGVRVVHEKKSAGVRVNH 33 466666666666666666666666665443 PP == domain 2 score: 4.2 bits; conditional E-value: 0.0041 Gp58 226 eskLddlraeftrsnqGmrveleskisGlqst 257 e k d++r ++ + + G+rv+ e + G+ FUN_002187-T1 67 ERKSDGVRVNHKKKSDGVRVDHEKRSDGVTVH 98 44555555555555555555555444443322 PP >> DAP_B D-aminopeptidase, domain B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.1 0.0073 27 30 78 .. 6 54 .. 1 72 [. 0.69 2 ? 7.0 0.3 0.002 7.4 21 72 .. 73 125 .. 67 130 .. 0.79 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0073 DAP_B 30 kvkiryaksaeklklvseneaesksvvaeidgdtlkierekenrtlkar 78 v ++y+k+++ +++v+e+++ +v e + d + ++ ek ++++ FUN_002187-T1 6 GVRVHYEKKSNGVRVVHEKKSAGVRVNHEKKSDGVGVNHEKKSDGVRVH 54 3778888888888888888888888877777777777766655555444 PP == domain 2 score: 7.0 bits; conditional E-value: 0.002 DAP_B 21 vtvekaek.gkvkiryaksaeklklvseneaesksvvaeidgdtlkiereken 72 v+v++++k v + ++k ++ +++ +e+++ ++ e++ d ++++ eke FUN_002187-T1 73 VRVNHKKKsDGVRVDHEKRSDGVTVHHEKKSDGVRLQHERNSDGVRVHHEKER 125 44544443334999999999999999999999999999999999999998885 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.1 3.8e+02 1 14 [. 12 25 .. 12 26 .. 0.86 2 ? 6.3 0.3 0.0035 13 1 24 [. 23 43 .. 23 45 .. 0.81 3 ? -2.0 0.0 1.4 5.2e+03 1 13 [. 45 57 .. 45 58 .. 0.79 4 ? 0.2 0.0 0.28 1e+03 1 14 [. 67 80 .. 67 84 .. 0.91 5 ? 0.8 0.0 0.19 6.8e+02 3 14 .. 80 91 .. 78 93 .. 0.83 6 ? 2.0 0.2 0.077 2.8e+02 1 14 [. 89 102 .. 89 103 .. 0.84 7 ? 4.0 0.1 0.018 67 1 13 [. 111 123 .. 111 127 .. 0.91 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.1 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002187-T1 12 EKKSNGVRVVHEKK 25 67899999****96 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0035 Beta-APP 1 eRQSAsyEVYHEKlVllaeDvGSN 24 e++SA+ V HEK+ ++ vG N FUN_002187-T1 23 EKKSAGVRVNHEKK---SDGVGVN 43 689**********8...6666655 PP == domain 3 score: -2.0 bits; conditional E-value: 1.4 Beta-APP 1 eRQSAsyEVYHEK 13 e++S + V H K FUN_002187-T1 45 EKKSDGVRVHHGK 57 5678899999988 PP == domain 4 score: 0.2 bits; conditional E-value: 0.28 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + V H K+ FUN_002187-T1 67 ERKSDGVRVNHKKK 80 799********996 PP == domain 5 score: 0.8 bits; conditional E-value: 0.19 Beta-APP 3 QSAsyEVYHEKl 14 +S + V HEK+ FUN_002187-T1 80 KSDGVRVDHEKR 91 67788999***8 PP == domain 6 score: 2.0 bits; conditional E-value: 0.077 Beta-APP 1 eRQSAsyEVYHEKl 14 e+ S + V HEK+ FUN_002187-T1 89 EKRSDGVTVHHEKK 102 56788999*****6 PP == domain 7 score: 4.0 bits; conditional E-value: 0.018 Beta-APP 1 eRQSAsyEVYHEK 13 eR S + V HEK FUN_002187-T1 111 ERNSDGVRVHHEK 123 799*********9 PP >> Tower Tower # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.11 3.9e+02 2 10 .. 12 20 .. 11 21 .. 0.88 2 ? -0.5 0.0 0.52 1.9e+03 2 10 .. 23 31 .. 22 31 .. 0.86 3 ? 1.2 0.0 0.15 5.6e+02 2 9 .. 34 41 .. 33 42 .. 0.86 4 ? 2.4 0.0 0.065 2.4e+02 2 10 .. 45 53 .. 44 62 .. 0.87 5 ? 0.1 0.0 0.35 1.3e+03 2 10 .. 67 75 .. 66 76 .. 0.88 6 ? -2.0 0.1 1.6 5.7e+03 3 10 .. 79 86 .. 78 86 .. 0.83 7 ? 2.5 0.0 0.06 2.2e+02 2 10 .. 89 97 .. 88 99 .. 0.93 8 ? 0.5 0.0 0.25 9.2e+02 2 8 .. 100 106 .. 99 108 .. 0.90 9 ? -2.5 0.0 2.2 8e+03 2 10 .. 111 119 .. 111 120 .. 0.84 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.11 Tower 2 EKksdGvfv 10 EKks+Gv v FUN_002187-T1 12 EKKSNGVRV 20 9*****976 PP == domain 2 score: -0.5 bits; conditional E-value: 0.52 Tower 2 EKksdGvfv 10 EKks Gv v FUN_002187-T1 23 EKKSAGVRV 31 9****9865 PP == domain 3 score: 1.2 bits; conditional E-value: 0.15 Tower 2 EKksdGvf 9 EKksdGv FUN_002187-T1 34 EKKSDGVG 41 9*****86 PP == domain 4 score: 2.4 bits; conditional E-value: 0.065 Tower 2 EKksdGvfv 10 EKksdGv v FUN_002187-T1 45 EKKSDGVRV 53 9*****987 PP == domain 5 score: 0.1 bits; conditional E-value: 0.35 Tower 2 EKksdGvfv 10 E+ksdGv v FUN_002187-T1 67 ERKSDGVRV 75 9*****976 PP == domain 6 score: -2.0 bits; conditional E-value: 1.6 Tower 3 KksdGvfv 10 KksdGv v FUN_002187-T1 79 KKSDGVRV 86 99**9865 PP == domain 7 score: 2.5 bits; conditional E-value: 0.06 Tower 2 EKksdGvfv 10 EK+sdGv+v FUN_002187-T1 89 EKRSDGVTV 97 9******98 PP == domain 8 score: 0.5 bits; conditional E-value: 0.25 Tower 2 EKksdGv 8 EKksdGv FUN_002187-T1 100 EKKSDGV 106 9*****7 PP == domain 9 score: -2.5 bits; conditional E-value: 2.2 Tower 2 EKksdGvfv 10 E+ sdGv v FUN_002187-T1 111 ERNSDGVRV 119 899999876 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.1 0.053 2e+02 57 77 .. 5 25 .. 3 31 .. 0.88 2 ? -0.4 0.1 0.42 1.5e+03 58 77 .. 28 47 .. 25 51 .. 0.85 3 ? 2.5 0.1 0.052 1.9e+02 57 77 .. 82 102 .. 66 104 .. 0.78 4 ? 1.6 0.1 0.1 3.8e+02 56 77 .. 103 124 .. 94 128 .. 0.80 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.053 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v+ +++++++ v++++k FUN_002187-T1 5 DGVRVHYEKKSNGVRVVHEKK 25 5999999********999987 PP == domain 2 score: -0.4 bits; conditional E-value: 0.42 ComGE 58 Gvevtvkenqeelivlesgk 77 Gv v+ +++++++ v +++k FUN_002187-T1 28 GVRVNHEKKSDGVGVNHEKK 47 89999999999999999876 PP == domain 3 score: 2.5 bits; conditional E-value: 0.052 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v ++ +++++v +++k FUN_002187-T1 82 DGVRVDHEKRSDGVTVHHEKK 102 688888888888888888876 PP == domain 4 score: 1.6 bits; conditional E-value: 0.1 ComGE 56 lNGvevtvkenqeelivlesgk 77 Gv ++ ++n++++ v ++++ FUN_002187-T1 103 SDGVRLQHERNSDGVRVHHEKE 124 5799999999999999999877 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 699 (0.0273635); expected 510.9 (0.02) Passed bias filter: 300 (0.011744); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1335.45 // Query: FUN_002188-T1 [L=160] Description: FUN_002188 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 13.1 2.1 4.1 8.3 0.2 2.4 2 tRNA_Me_trans_C Aminomethyltransferase beta-barrel domain 0.24 12.1 1.2 1.7 9.4 0.3 2.6 2 SPP1_Dit Siphovirus-type tail component, C-terminal d 0.44 10.7 9.5 6.6 6.8 0.8 3.5 4 DNA_ligase_A_M ATP dependent DNA ligase domain 2.6 8.5 15.5 46 4.5 0.0 6.6 8 Beta-APP Beta-amyloid peptide (beta-APP) 8 7.4 16.5 6.2 7.8 1.8 4.3 4 DUF2554 Protein of unknown function (DUF2554) Domain annotation for each model (and alignments): >> tRNA_Me_trans_C Aminomethyltransferase beta-barrel domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 0.2 0.0008 4.1 7 57 .. 49 98 .. 41 100 .. 0.73 2 ? 4.1 0.1 0.017 86 25 57 .. 109 142 .. 100 144 .. 0.80 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0008 tRNA_Me_trans_C 7 kelnwladkekkeelecevkvRhrqepvkakvelkdd.etveveldepvrav 57 k+ nw++d+ + + + v+v h+++ + v ++++ + v+v+ +++ ++v FUN_002188-T1 49 KSSNWVRDDHE--KKSAGVRVNHEKNSDGVGVHHEKKsDGVRVHHENKRDGV 98 56799999998..556666666666665555555554499****99999988 PP == domain 2 score: 4.1 bits; conditional E-value: 0.017 tRNA_Me_trans_C 25 vkvRhrqepvkakvelkdd.etveveldepvrav 57 v+v +++++ +kv +++ + v+v+ +++ ++v FUN_002188-T1 109 VRVNYEKKNDGVKVDHENRsNGVTVHHEKKSDGV 142 7888888888888888877799999999998887 PP >> SPP1_Dit Siphovirus-type tail component, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.4 0.3 0.00033 1.7 11 58 .. 88 136 .. 82 147 .. 0.76 2 ? 3.3 0.1 0.026 1.3e+02 14 50 .. 124 159 .. 118 160 .] 0.75 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00033 SPP1_Dit 11 tvtftaaasefklenqeggkfirvnytfsagdvlvIdcekrk..vtlnGe 58 +v+ +++ + +++ ++ +++ +rvny+ ++d +++d e+r+ vt+ e FUN_002188-T1 88 RVHHENKRDGVRVYHKRKSDGVRVNYEK-KNDGVKVDHENRSngVTVHHE 136 566677888999**************96.99******7666422666555 PP == domain 2 score: 3.3 bits; conditional E-value: 0.026 SPP1_Dit 14 ftaaasefklenqeggkfirvnytfsagdvlvIdcek 50 ++ ++ +++ ++++++ +r++++ ++d +++d ek FUN_002188-T1 124 HENRSNGVTVHHEKKSDGVRLQHER-KSDGVKVDHEK 159 5556667899999999999998886.78888888776 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.1 1.1 5.4e+03 25 39 .. 34 49 .. 29 55 .. 0.62 2 ? 6.8 0.8 0.0013 6.6 22 50 .. 78 106 .. 65 114 .. 0.72 3 ? 3.7 0.5 0.012 61 22 43 .. 100 121 .. 94 124 .. 0.80 4 ? 6.7 0.1 0.0014 7.2 19 43 .. 130 154 .. 123 156 .. 0.84 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 1.1 DNA_ligase_A_M 25 EiKyDGeR.aqvhkeg 39 E K DG + vh e+ FUN_002188-T1 34 EKKRDGSDgVRVHHEK 49 6676666555566433 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0013 DNA_ligase_A_M 22 fivEiKyDGeRaqvhkegdevklfSRnle 50 ++ E K DG+R+ ++++d v+++ ++ FUN_002188-T1 78 VHHEKKSDGVRVHHENKRDGVRVYHKRKS 106 56678888888888888888877765544 PP == domain 3 score: 3.7 bits; conditional E-value: 0.012 DNA_ligase_A_M 22 fivEiKyDGeRaqvhkegdevk 43 ++ K DG+R+ +k++d vk FUN_002188-T1 100 VYHKRKSDGVRVNYEKKNDGVK 121 5667899999999999998887 PP == domain 4 score: 6.7 bits; conditional E-value: 0.0014 DNA_ligase_A_M 19 gkafivEiKyDGeRaqvhkegdevk 43 g +++ E K DG+R+q ++++d vk FUN_002188-T1 130 GVTVHHEKKSDGVRLQHERKSDGVK 154 556778*************999987 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.012 63 2 14 .. 2 14 .. 1 21 [. 0.89 2 ? -0.1 0.0 0.25 1.3e+03 5 13 .. 41 49 .. 38 56 .. 0.82 3 ? 4.5 0.0 0.009 46 1 14 [. 59 72 .. 59 78 .. 0.88 4 ? 0.4 0.3 0.18 9.1e+02 4 14 .. 73 83 .. 71 91 .. 0.84 5 ? -1.0 0.1 0.48 2.5e+03 1 13 [. 81 93 .. 81 95 .. 0.80 6 ? -1.2 0.1 0.58 3e+03 9 13 .. 100 104 .. 96 116 .. 0.67 7 ? 1.5 0.1 0.079 4e+02 3 14 .. 127 138 .. 125 139 .. 0.83 8 ? 2.2 0.1 0.051 2.6e+02 1 13 [. 147 159 .. 147 160 .] 0.93 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.012 Beta-APP 2 RQSAsyEVYHEKl 14 R S + V HEK+ FUN_002188-T1 2 RRSDGVRVHHEKR 14 889999******9 PP == domain 2 score: -0.1 bits; conditional E-value: 0.25 Beta-APP 5 AsyEVYHEK 13 + V HEK FUN_002188-T1 41 DGVRVHHEK 49 57789***9 PP == domain 3 score: 4.5 bits; conditional E-value: 0.009 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V HEK FUN_002188-T1 59 EKKSAGVRVNHEKN 72 689*********95 PP == domain 4 score: 0.4 bits; conditional E-value: 0.18 Beta-APP 4 SAsyEVYHEKl 14 S + V HEK+ FUN_002188-T1 73 SDGVGVHHEKK 83 667789***96 PP == domain 5 score: -1.0 bits; conditional E-value: 0.48 Beta-APP 1 eRQSAsyEVYHEK 13 e++S + V HE FUN_002188-T1 81 EKKSDGVRVHHEN 93 56788999***95 PP == domain 6 score: -1.2 bits; conditional E-value: 0.58 Beta-APP 9 VYHEK 13 VYH + FUN_002188-T1 100 VYHKR 104 77754 PP == domain 7 score: 1.5 bits; conditional E-value: 0.079 Beta-APP 3 QSAsyEVYHEKl 14 S + V HEK+ FUN_002188-T1 127 RSNGVTVHHEKK 138 688999*****6 PP == domain 8 score: 2.2 bits; conditional E-value: 0.051 Beta-APP 1 eRQSAsyEVYHEK 13 eR+S + V HEK FUN_002188-T1 147 ERKSDGVKVDHEK 159 89**********9 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 3.4 0.24 1.2e+03 49 54 .. 30 35 .. 3 64 .. 0.51 2 ? 7.8 1.8 0.0012 6.2 35 66 .. 63 94 .. 51 106 .. 0.78 3 ? 1.3 0.0 0.12 6.4e+02 38 63 .. 99 124 .. 92 128 .. 0.80 4 ? 3.9 0.3 0.02 1e+02 37 61 .. 131 155 .. 116 159 .. 0.71 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.24 DUF2554 49 ravaee 54 a e+ FUN_002188-T1 30 GADHEK 35 333222 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0012 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfywq 66 ++ ++ he +sd + e+ ++G+r h+ + FUN_002188-T1 63 AGVRVNHEKNSDGVGVHHEKKSDGVRVHHENK 94 56677888888888888888888888888654 PP == domain 3 score: 1.3 bits; conditional E-value: 0.12 DUF2554 38 qlrheadsdelravaeesaeGlrehf 63 ++ h+ sd +r e+ +G++ + FUN_002188-T1 99 RVYHKRKSDGVRVNYEKKNDGVKVDH 124 56799999999999999999998655 PP == domain 4 score: 3.9 bits; conditional E-value: 0.02 DUF2554 37 hqlrheadsdelravaeesaeGlre 61 + he sd +r e ++G++ FUN_002188-T1 131 VTVHHEKKSDGVRLQHERKSDGVKV 155 4567888888888888888877765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 857 (0.0335486); expected 510.9 (0.02) Passed bias filter: 293 (0.01147); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1578.52 // Query: FUN_002189-T1 [L=143] Description: FUN_002189 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.035 14.3 9.4 1.7 8.7 0.4 3.5 3 DNA_ligase_A_M ATP dependent DNA ligase domain 0.18 12.5 2.8 18 6.1 0.2 3.1 3 SPP1_Dit Siphovirus-type tail component, C-terminal do 0.29 11.6 1.4 36 4.9 0.1 3.0 3 PH_FT_C PH domain found in tandem in fungal proteins 0.31 11.5 2.6 1.8 8.9 0.3 2.0 2 DAP_B D-aminopeptidase, domain B 0.4 11.6 9.6 2.5 9.0 0.9 3.7 3 DUF2554 Protein of unknown function (DUF2554) Domain annotation for each model (and alignments): >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.1 0.059 3e+02 24 44 .. 19 39 .. 7 51 .. 0.73 2 ? 7.9 0.9 0.00059 3 21 51 .. 60 90 .. 50 112 .. 0.77 3 ? 8.7 0.4 0.00034 1.7 19 44 .. 113 138 .. 98 139 .. 0.86 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.059 DNA_ligase_A_M 24 vEiKyDGeRaqvhkegdevkl 44 K DG+R+ +k+++ v++ FUN_002189-T1 19 TIRKSDGVRVHDDKKSNGVRV 39 457889999888887777665 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00059 DNA_ligase_A_M 21 afivEiKyDGeRaqvhkegdevklfSRnled 51 ++ E K DG+R+ ++++d v+l+ ++ d FUN_002189-T1 60 GVHHEKKSDGVRVHHENKRDGVRLYHKRKSD 90 56789999****9999999999999766554 PP == domain 3 score: 8.7 bits; conditional E-value: 0.00034 DNA_ligase_A_M 19 gkafivEiKyDGeRaqvhkegdevkl 44 g +++ E K DG+R+q +k++devk+ FUN_002189-T1 113 GVTVHHEKKSDGVRLQHEKKSDEVKV 138 556778*****************985 PP >> SPP1_Dit Siphovirus-type tail component, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.079 4e+02 32 58 .. 26 53 .. 4 62 .. 0.48 2 ? 5.6 0.1 0.0052 26 11 51 .. 71 110 .. 60 116 .. 0.74 3 ? 6.1 0.2 0.0035 18 12 50 .. 105 142 .. 102 143 .] 0.81 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.079 SPP1_Dit 32 irvnytfsag.dvlvIdcekrkvtlnGe 58 +rv+ + +++ ++v + ++ v++n e FUN_002189-T1 26 VRVHDDKKSNgVRVVHEKKSAGVRVNHE 53 3443333222022222344444555444 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0052 SPP1_Dit 11 tvtftaaasefklenqeggkfirvnytfsagdvlvIdcekr 51 +v+ +++ + ++l ++ +++ + vny+ ++d +++d e+r FUN_002189-T1 71 RVHHENKRDGVRLYHKRKSDGVMVNYEK-KSDGVKVDHENR 110 4555666777888888888888888885.778888887776 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0035 SPP1_Dit 12 vtftaaasefklenqeggkfirvnytfsagdvlvIdcek 50 v ++ ++ +++ ++++++ +r++++ ++d++++d ek FUN_002189-T1 105 VDHENRSDGVTVHHEKKSDGVRLQHEK-KSDEVKVDHEK 142 55666778899999999999**99986.89999999887 PP >> PH_FT_C PH domain found in tandem in fungal proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.014 73 7 31 .. 27 51 .. 21 59 .. 0.80 2 ? 0.6 0.0 0.15 7.4e+02 14 35 .. 56 77 .. 43 86 .. 0.69 3 ? 4.9 0.1 0.007 36 7 39 .. 104 136 .. 98 138 .. 0.81 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.014 PH_FT_C 7 eIlddgyehaLrvyrdrksgavRLe 31 +++dd+ rv +++ks +vR++ FUN_002189-T1 27 RVHDDKKSNGVRVVHEKKSAGVRVN 51 6788888888999999999999975 PP == domain 2 score: 0.6 bits; conditional E-value: 0.15 PH_FT_C 14 ehaLrvyrdrksgavRLeasvl 35 v +++ks++vR++ + FUN_002189-T1 56 SDGVGVHHEKKSDGVRVHHENK 77 5556678888888888876554 PP == domain 3 score: 4.9 bits; conditional E-value: 0.007 PH_FT_C 7 eIlddgyehaLrvyrdrksgavRLeasvlrGel 39 ++ +++ +v +++ks++vRL+ ++ e+ FUN_002189-T1 104 KVDHENRSDGVTVHHEKKSDGVRLQHEKKSDEV 136 566677777789*************98887776 PP >> DAP_B D-aminopeptidase, domain B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.2 0.013 66 21 66 .. 38 83 .. 9 90 .. 0.58 2 ? 8.9 0.3 0.00036 1.8 27 76 .. 88 137 .. 80 143 .] 0.74 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.013 DAP_B 21 vtvekaekgkvkiryaksaeklklvseneaesksvvaeidgdtlki 66 v++++++ v ++++k+++ + + +e+++ +v e ++d +++ FUN_002189-T1 38 RVVHEKKSAGVRVNHEKNSDGVGVHHEKKSDGVRVHHENKRDGVRL 83 2233333344666666666666666666665555555555555555 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00036 DAP_B 27 ekgkvkiryaksaeklklvseneaesksvvaeidgdtlkierekenrtlk 76 ++ v+++y+k+++ +k+ +en++ +v e + d ++++ ek ++k FUN_002189-T1 88 KSDGVMVNYEKKSDGVKVDHENRSDGVTVHHEKKSDGVRLQHEKKSDEVK 137 33449999999999999999999999999988888888888776555444 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.04 2e+02 29 63 .. 18 52 .. 4 58 .. 0.72 2 ? 9.0 0.9 0.00049 2.5 34 66 .. 45 77 .. 33 92 .. 0.78 3 ? 4.5 1.0 0.013 64 41 64 .. 107 130 .. 87 143 .] 0.59 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.04 DUF2554 29 fvwvktvdhqlrheadsdelravaeesaeGlrehf 63 f k+ + ++ + s+ +r v e+ + G+r + FUN_002189-T1 18 FTIRKSDGVRVHDDKKSNGVRVVHEKKSAGVRVNH 52 55555666666677788888999998888888766 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00049 DUF2554 34 tvdhqlrheadsdelravaeesaeGlrehfywq 66 +++ ++ he +sd + e+ ++G+r h+ + FUN_002189-T1 45 SAGVRVNHEKNSDGVGVHHEKKSDGVRVHHENK 77 456677888888888888888888888888654 PP == domain 3 score: 4.5 bits; conditional E-value: 0.013 DUF2554 41 headsdelravaeesaeGlrehfy 64 he sd + e+ ++G+r + FUN_002189-T1 107 HENRSDGVTVHHEKKSDGVRLQHE 130 555555555555555555544333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (143 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 691 (0.0270503); expected 510.9 (0.02) Passed bias filter: 242 (0.00947348); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1447.71 // Query: FUN_002190-T1 [L=290] Description: FUN_002190 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00044 20.4 2.7 0.062 13.3 0.8 2.7 2 SlipAM Surface lipoprotein assembly modifier ------ inclusion threshold ------ 0.31 12.0 34.5 2.1 9.3 2.0 6.9 7 DUF2554 Protein of unknown function (DUF2554) 0.46 10.5 11.5 3.9 7.4 0.7 3.5 4 DUF1444 Protein of unknown function (DUF1444) 4.9 7.3 8.3 1.5 9.0 1.0 2.8 3 DUF6591 Family of unknown function (DUF6591) 5.7 7.4 34.8 4.5 7.8 0.3 10.0 13 Beta-APP Beta-amyloid peptide (beta-APP) Domain annotation for each model (and alignments): >> SlipAM Surface lipoprotein assembly modifier # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.9 0.1 0.0022 11 68 123 .. 60 128 .. 21 154 .. 0.79 2 ! 13.3 0.8 1.2e-05 0.062 67 155 .. 155 266 .. 142 272 .. 0.80 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0022 SlipAM 68 sGklYwdnkkyddlstraglGigyknaktdvsllPfyekrfy.............gndryskasGvrle 123 +G + ++kk+ ++ r + G++ +++k+ ++++++ek+++ + ++ +k+ Gvr++ FUN_002190-T1 60 DGLSVDHEKKSHGFTIRKSDGVRVHDEKKSNGVRVVHEKKSAgvrvnhekksdgvADHHEKKSDGVRVH 128 555666888999999999999999999999999999999999887777777776655555556677665 PP == domain 2 score: 13.3 bits; conditional E-value: 1.2e-05 SlipAM 67 vsGklYwdnkkyddlstraglGigyknaktdvsllPfyekrfy........................gndryskasGvrlelnswlsekwqlslal 138 +G +++kk+d ++ r+ G++ ++k+ ++++++ek+++ ++ +k Gvr ++ ++ s+ +++++ FUN_002190-T1 155 SEGVRVYHEKKSDGFTIRTRDGVRVVHEKKSNGVRVVHEKKSAgvrvnhekksdgvgvhheeksdvvRVHHEKKRVGVRAYH-ERKSDGVRVYHEK 249 45544459***********************************999988888888887777777777777777777998765.4568888899999 PP SlipAM 139 eyekerytkrkhldGnr 155 + ++++++k++dG r FUN_002190-T1 250 KSDGKKFHHEKKSDGVR 266 88888998888888876 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.6 0.0092 47 41 64 .. 22 45 .. 4 58 .. 0.82 2 ? 6.1 1.0 0.0042 21 24 64 .. 68 108 .. 62 122 .. 0.77 3 ? 3.2 0.3 0.034 1.7e+02 36 63 .. 102 129 .. 99 137 .. 0.82 4 ? 3.4 0.8 0.029 1.5e+02 39 64 .. 138 163 .. 121 169 .. 0.81 5 ? 4.8 0.1 0.011 54 35 64 .. 175 204 .. 163 209 .. 0.79 6 ? 4.1 1.4 0.017 86 38 66 .. 200 228 .. 195 247 .. 0.69 7 ? 9.3 2.0 0.00041 2.1 34 64 .. 251 281 .. 239 289 .. 0.85 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0092 DUF2554 41 headsdelravaeesaeGlrehfy 64 he sd l e+ +G+r h++ FUN_002190-T1 22 HEKKSDGLSVDHEKKRDGVRVHHK 45 899999999999999999999986 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0042 DUF2554 24 qkdhefvwvktvdhqlrheadsdelravaeesaeGlrehfy 64 +k h f k+ + ++ e s+ +r v e+ + G+r + FUN_002190-T1 68 KKSHGFTIRKSDGVRVHDEKKSNGVRVVHEKKSAGVRVNHE 108 67788888888888888888888888888888888887664 PP == domain 3 score: 3.2 bits; conditional E-value: 0.034 DUF2554 36 dhqlrheadsdelravaeesaeGlrehf 63 + ++ he sd + e+ ++G+r h FUN_002190-T1 102 GVRVNHEKKSDGVADHHEKKSDGVRVHR 129 6678899999999999999999999986 PP == domain 4 score: 3.4 bits; conditional E-value: 0.029 DUF2554 39 lrheadsdelravaeesaeGlrehfy 64 + he s +r e+ +eG+r ++ FUN_002190-T1 138 VDHEKKSHGVRVDHEKKSEGVRVYHE 163 56899999999999999999998775 PP == domain 5 score: 4.8 bits; conditional E-value: 0.011 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfy 64 + ++ he s+ +r v e+ + G+r + FUN_002190-T1 175 DGVRVVHEKKSNGVRVVHEKKSAGVRVNHE 204 556788******************998775 PP == domain 6 score: 4.1 bits; conditional E-value: 0.017 DUF2554 38 qlrheadsdelravaeesaeGlrehfywq 66 ++ he sd + ee ++ +r h+ + FUN_002190-T1 200 RVNHEKKSDGVGVHHEEKSDVVRVHHEKK 228 56677777777777777777777777543 PP == domain 7 score: 9.3 bits; conditional E-value: 0.00041 DUF2554 34 tvdhqlrheadsdelravaeesaeGlrehfy 64 + ++++ he sd +r e ++G+r h+ FUN_002190-T1 251 SDGKKFHHEKKSDGVRLQHERNSDGVRVHHE 281 5678899**********************96 PP >> DUF1444 Protein of unknown function (DUF1444) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.079 4e+02 16 43 .. 26 53 .. 18 55 .. 0.82 2 ? 7.4 0.7 0.00077 3.9 11 78 .. 43 110 .. 33 121 .. 0.84 3 ? 7.2 0.9 0.00093 4.7 13 78 .. 141 206 .. 130 246 .. 0.83 4 ? 1.2 0.1 0.062 3.2e+02 15 44 .. 250 279 .. 238 284 .. 0.82 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.079 DUF1444 16 eeevtlkfdreedtlriedkktkkgvti 43 ++ ++ +++++d +r+++k++ +gv + FUN_002190-T1 26 SDGLSVDHEKKRDGVRVHHKRKSNGVRV 53 566788899999999**99999999977 PP == domain 2 score: 7.4 bits; conditional E-value: 0.00077 DUF1444 11 eeklkeeevtlkfdreedtlriedkktkkgvtiklkeliakyeekkekaidevveyveealkalkeea 78 ++k k++ v++ ++r++d l + ++k+ +g ti+ ++ + ++ekk + ++ v e+ + ++++ +e++ FUN_002190-T1 43 HHKRKSNGVRVDHERKRDGLSVDHEKKSHGFTIRKSDGVRVHDEKKSNGVRVVHEKKSAGVRVNHEKK 110 566678889999***************************99999999999998888888777665554 PP == domain 3 score: 7.2 bits; conditional E-value: 0.00093 DUF1444 13 klkeeevtlkfdreedtlriedkktkkgvtiklkeliakyeekkekaidevveyveealkalkeea 78 + k++ v++ ++++++ +r+ ++k+ g ti+ ++ + +ekk + ++ v e+ + ++++ +e++ FUN_002190-T1 141 EKKSHGVRVDHEKKSEGVRVYHEKKSDGFTIRTRDGVRVVHEKKSNGVRVVHEKKSAGVRVNHEKK 206 55667788999999*******************************999999888888887766554 PP == domain 4 score: 1.2 bits; conditional E-value: 0.062 DUF1444 15 keeevtlkfdreedtlriedkktkkgvtik 44 k++ ++++++++d +r++++++ gv ++ FUN_002190-T1 250 KSDGKKFHHEKKSDGVRLQHERNSDGVRVH 279 556778999999999999999999999875 PP >> DUF6591 Family of unknown function (DUF6591) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 0.74 3.8e+03 57 75 .. 6 24 .. 3 43 .. 0.48 2 ? 9.0 1.0 0.0003 1.5 54 119 .. 58 123 .. 53 144 .. 0.76 3 ? 1.9 0.3 0.045 2.3e+02 54 91 .. 154 191 .. 125 234 .. 0.60 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.74 DUF6591 57 GFtvDYekgdksfnaddaa 75 G vD ek ++ + d ++ FUN_002190-T1 6 GVRVDHEKRSDCVRDDHEK 24 5566666655555443321 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0003 DUF6591 54 sdkGFtvDYekgdksfnaddaaGysvsisykgnnvmsiqikapdseeedaakedsessdeadtsae 119 + G +vD ek ++ f+ ++G +v+ + k n v +++ k++ + +k+ + +d+++++++ FUN_002190-T1 58 KRDGLSVDHEKKSHGFTIRKSDGVRVHDEKKSNGVRVVHEKKSAGVRVNHEKKSDGVADHHEKKSD 123 568******************************999999988864555555555555565555444 PP == domain 3 score: 1.9 bits; conditional E-value: 0.045 DUF6591 54 sdkGFtvDYekgdksfnaddaaGysvsisykgnnvmsi 91 + +G v ek ++ f+ +G +v + k n v ++ FUN_002190-T1 154 KSEGVRVYHEKKSDGFTIRTRDGVRVVHEKKSNGVRVV 191 33444455555555555555555555444444444444 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.11 5.5e+02 2 14 .. 2 14 .. 1 20 [. 0.91 2 ? -0.5 0.0 0.35 1.8e+03 1 14 [. 23 36 .. 23 37 .. 0.85 3 ? -1.4 0.0 0.64 3.3e+03 2 13 .. 46 57 .. 45 66 .. 0.85 4 ? -1.7 0.0 0.8 4.1e+03 1 14 [. 56 69 .. 56 70 .. 0.78 5 ? -0.0 0.0 0.24 1.2e+03 1 14 [. 86 99 .. 86 99 .. 0.85 6 ? 3.8 0.1 0.016 81 1 14 [. 97 110 .. 97 112 .. 0.91 7 ? -0.9 0.1 0.44 2.3e+03 1 14 [. 141 154 .. 141 156 .. 0.84 8 ? 5.0 0.5 0.0066 34 1 14 [. 152 165 .. 152 166 .. 0.85 9 ? 0.2 0.0 0.2 1e+03 1 14 [. 182 195 .. 182 196 .. 0.86 10 ? 4.1 0.1 0.013 65 1 14 [. 193 206 .. 193 213 .. 0.89 11 ? -1.4 0.1 0.63 3.2e+03 8 14 .. 222 228 .. 215 230 .. 0.76 12 ? 7.8 0.3 0.00088 4.5 1 14 [. 237 250 .. 237 251 .. 0.93 13 ? 2.6 0.1 0.036 1.8e+02 1 13 [. 270 282 .. 270 286 .. 0.91 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.11 Beta-APP 2 RQSAsyEVYHEKl 14 R+S + V HEK+ FUN_002190-T1 2 RKSDGVRVDHEKR 14 8899999*****8 PP == domain 2 score: -0.5 bits; conditional E-value: 0.35 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002190-T1 23 EKKSDGLSVDHEKK 36 57899999****96 PP == domain 3 score: -1.4 bits; conditional E-value: 0.64 Beta-APP 2 RQSAsyEVYHEK 13 R+S + V HE+ FUN_002190-T1 46 RKSNGVRVDHER 57 8999999***96 PP == domain 4 score: -1.7 bits; conditional E-value: 0.8 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+ + V HEK+ FUN_002190-T1 56 ERKRDGLSVDHEKK 69 5667788899**96 PP == domain 5 score: -0.0 bits; conditional E-value: 0.24 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002190-T1 86 EKKSNGVRVVHEKK 99 57899999****95 PP == domain 6 score: 3.8 bits; conditional E-value: 0.016 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V HEK+ FUN_002190-T1 97 EKKSAGVRVNHEKK 110 689**********6 PP == domain 7 score: -0.9 bits; conditional E-value: 0.44 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002190-T1 141 EKKSHGVRVDHEKK 154 56788999****96 PP == domain 8 score: 5.0 bits; conditional E-value: 0.0066 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + VYHEK+ FUN_002190-T1 152 EKKSEGVRVYHEKK 165 57899999*****6 PP == domain 9 score: 0.2 bits; conditional E-value: 0.2 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002190-T1 182 EKKSNGVRVVHEKK 195 57899999****96 PP == domain 10 score: 4.1 bits; conditional E-value: 0.013 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V HEK+ FUN_002190-T1 193 EKKSAGVRVNHEKK 206 689**********7 PP == domain 11 score: -1.4 bits; conditional E-value: 0.63 Beta-APP 8 EVYHEKl 14 V HEK+ FUN_002190-T1 222 RVHHEKK 228 699**95 PP == domain 12 score: 7.8 bits; conditional E-value: 0.00088 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + VYHEK+ FUN_002190-T1 237 ERKSDGVRVYHEKK 250 89***********6 PP == domain 13 score: 2.6 bits; conditional E-value: 0.036 Beta-APP 1 eRQSAsyEVYHEK 13 eR S + V HEK FUN_002190-T1 270 ERNSDGVRVHHEK 282 799*********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (290 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 830 (0.0324917); expected 510.9 (0.02) Passed bias filter: 265 (0.0103739); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.40s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 2931.76 // Query: FUN_002192-T1 [L=338] Description: FUN_002192 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 16.5 0.0 0.022 15.7 0.0 1.4 1 DUF8039 Domain of unknown function (DUF8039) Domain annotation for each model (and alignments): >> DUF8039 Domain of unknown function (DUF8039) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 8.8e-07 0.022 15 62 .. 246 290 .. 236 305 .. 0.83 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 8.8e-07 DUF8039 15 vvkvknksivvArgtvypvsegktvhgvklkegyvkVqVdevvdgfed 62 vv + ++s +vA g v+ +e ++hg+++++g+v V + ++++++ FUN_002192-T1 246 VV-YLKNSTIVAGGRVQTDRE--MIHGCRIPPGHVCVMLTTAHPNHAA 290 34.5667899******98885..79****************9999874 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (338 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 636 (0.0248972); expected 510.9 (0.02) Passed bias filter: 483 (0.0189078); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 3370.40 // Query: FUN_002193-T1 [L=453] Description: FUN_002193 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.018 15.6 1.0 0.059 13.9 1.0 1.8 1 zf-NOSIP Zinc-finger of nitric oxide synthase-interacting pr 0.022 15.7 0.8 8.5 7.4 0.0 2.7 2 FOXP-CC FOXP coiled-coil domain 0.18 12.3 2.3 0.5 10.9 0.2 2.1 2 ROS_MUCR ROS/MUCR transcriptional regulator protein Domain annotation for each model (and alignments): >> zf-NOSIP Zinc-finger of nitric oxide synthase-interacting protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 1.0 7e-06 0.059 36 66 .. 369 400 .. 365 405 .. 0.85 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 7e-06 zf-NOSIP 36 aikdfdccslslq.pcrdpvltedgylyekea 66 ikd c l+ + cr pvl ed yly k a FUN_002193-T1 369 MIKDCLACDLTDRgQCRCPVLPEDFYLYCKGA 400 589999999986537*************9987 PP >> FOXP-CC FOXP coiled-coil domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.001 8.5 4 38 .. 70 104 .. 69 108 .. 0.90 2 ? 5.4 0.6 0.0042 36 7 34 .. 121 145 .. 117 150 .. 0.82 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.001 FOXP-CC 4 sgvCkWPgCekvledveeflkHlqseHslddksta 38 gvC+ gC + + ++++ +Hl ++H+ ++t FUN_002193-T1 70 DGVCRIAGCPQRGKYLKRLDNHLLRSHKGITRATN 104 69*************************98888776 PP == domain 2 score: 5.4 bits; conditional E-value: 0.0042 FOXP-CC 7 CkWPgCekvledveeflkHlqseHsldd 34 C+ P C k +v+++++H+++ Hsl+ FUN_002193-T1 121 CRFPSCGK---QVMHLHNHVKNVHSLEM 145 ******97...57889999999998865 PP >> ROS_MUCR ROS/MUCR transcriptional regulator protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.1 0.11 9e+02 67 85 .. 78 96 .. 76 107 .. 0.81 2 ? 10.9 0.2 5.9e-05 0.5 69 99 .. 125 155 .. 115 160 .. 0.91 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.11 ROS_MUCR 67 cledGkkfKsLkrhLktah 85 c + Gk +K L hL ++h FUN_002193-T1 78 CPQRGKYLKRLDNHLLRSH 96 66789******99997776 PP == domain 2 score: 10.9 bits; conditional E-value: 5.9e-05 ROS_MUCR 69 edGkkfKsLkrhLktahgltpeeYrekwglp 99 +Gk++ L+ h+k+ h l+ ++Y+ ++ + FUN_002193-T1 125 SCGKQVMHLHNHVKNVHSLEMKDYKLRFATE 155 5************************999765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (453 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 840 (0.0328831); expected 510.9 (0.02) Passed bias filter: 431 (0.0168722); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 4511.03 // Query: FUN_002194-T1 [L=1208] Description: FUN_002194 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-29 103.5 6.4 1.8e-29 103.5 6.4 1.7 2 KDZ Kyakuja-Dileera-Zisupton transposase 1.6e-23 83.1 1.5 1.6e-23 83.1 1.5 2.5 2 CxC3 CxC3 like cysteine cluster associated with K Domain annotation for each model (and alignments): >> KDZ Kyakuja-Dileera-Zisupton transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.1 0.77 9.8e+03 26 75 .. 25 71 .. 9 83 .. 0.47 2 ! 103.5 6.4 1.4e-33 1.8e-29 4 217 .] 391 605 .. 388 605 .. 0.87 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 0.77 KDZ 26 ldgsayfleeee....vdkfkdeveekekstCasrwkaaaeaetkktwkgfdet 75 +s+ fl++++ ++ +d v + +C+ ++ a ++++ +gf+ t FUN_002194-T1 25 ISQSKAFLKNKRkarhLEFSTDPVSGH--RSCKGTYSAEKRQK-----QGFEST 71 555555555555444222222223333..77766665544333.....344444 PP == domain 2 score: 103.5 bits; conditional E-value: 1.4e-33 KDZ 4 llamDgNfslkrvskk.skdprlldgsayfleeeevdkfkdeveek.......ekstC.asrwkaaaeaetkktwkgfdetGifavlCrHglvlgv 90 + +DgN +l r++++ +++++ g++++ ++++vd++ ++v + +++ C +s+w+aa ++ +kk k++ etG+ ++ CrH + + + FUN_002194-T1 391 SVHVDGNMKLYRFKSAgVSKRECYYGETFVASNAKVDSHIHKVYQGvkhnkeiQQKMCgDSSWHAAGNTIKKK--KNLCETGLEIAGCRHAVAQHA 484 5789***********64666667999999999999888887775554444444448883568******99999..9******************** PP KDZ 91 adlvksgelakydlalvskllevlged.lgisYDIgCqfsktlakssllpelakekrlrflvpafHgyaHnrkCqlryspnyiegvGledgEgcEr 185 +++ ++ + + ++ ++ +l ++ +++ YD++C++ + k+++ + +++++ + +++H++aH + Cq+ + +++ g+G + gE++E+ FUN_002194-T1 485 VNMMYGEVYGYAHYMQLNYFLP---KNvQFFWYDVVCKYWPWIGKHNK----EVTEKMKPALSVMHAKAHAWYCQVLWGGRWQVGAGATTGEEVEQ 573 *******776666666666655...441589************99998....7899**************************************** PP KDZ 186 lwsksnalasstreaspghrhqalddhfkqwn 217 + s+ + l sst+++ p +r ++l +h qwn FUN_002194-T1 574 INSHFSRLGSSTKHMLPEAREELLTEHALQWN 605 *******************************9 PP >> CxC3 CxC3 like cysteine cluster associated with KDZ transposases # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.1 1.5 1.3e-27 1.6e-23 11 112 .. 243 345 .. 237 346 .. 0.89 2 ? -2.3 0.1 0.4 5.2e+03 32 87 .. 1141 1158 .. 1116 1182 .. 0.52 Alignments for each domain: == domain 1 score: 83.1 bits; conditional E-value: 1.3e-27 CxC3 11 cceeCkktgtltlkagsesiavvtkeGrfdlnsaafkcssCsavreatledyi..esGfwpgspkessylfseellllwyhlkhkspgtSerkfie 104 c+ C +++ ++++ ++++vv+ Grfdl a+++c++C++ + +i ++Gfwpgs+++ +y+f ++l+ +w l++++pg+Ser f++ FUN_002194-T1 243 SCPVCDSICKRLTNQHGQHCIVVSARGRFDLYHACYQCCNCNKELST-SNPFIvsQLGFWPGSISDVTYIFHQDLFIHWDILQKQTPGISERSFLK 337 68899999997778888*************************99984.445551267*************************************** PP CxC3 105 tleevske 112 +le +sk+ FUN_002194-T1 338 SLELFSKQ 345 *****997 PP == domain 2 score: -2.3 bits; conditional E-value: 0.4 CxC3 32 vvtkeGrfdlnsaafkcssCsavreatledyiesGfwpgspkessylfseellllw 87 +++++ +f l+++ +++ FUN_002194-T1 1141 IINEKTSFFLTTS--------------------------------------NEEVM 1158 4554444444433......................................33333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1208 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1433 (0.0560971); expected 510.9 (0.02) Passed bias filter: 659 (0.0257976); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.45u 0.39s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 11584.73 // Query: FUN_002195-T1 [L=268] Description: FUN_002195 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-19 68.6 1.6 1.3e-18 68.0 1.6 1.2 1 Cation_efflux Cation efflux transmembrane domain Domain annotation for each model (and alignments): >> Cation_efflux Cation efflux transmembrane domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.0 1.6 5e-23 1.3e-18 25 138 .. 9 120 .. 5 143 .. 0.89 Alignments for each domain: == domain 1 score: 68.0 bits; conditional E-value: 5e-23 Cation_efflux 25 lalladalhsladlisslvlllalrlsrkppderhpfGhgrlevlaalvvsilllvlgvfllleaierllaepgeevnpglalilalvsllvnlll 120 al++ ++ +++dl+s+l++ll+l++s ++p+ +++fG++r+evla +++ +l++++g+f++ e+ erll ++ev + +l +a+v+l++ ll+ FUN_002195-T1 9 KALTSFSYLTIFDLLSLLTCLLSLWVSLQKPSTTFSFGYERFEVLAVFSSTVLVMFGGLFIVKESTERLL--MPSEVITDNLLPAAAVGLFLHLLV 102 5899999********************8889***************************************..899999999999999999999999 PP Cation_efflux 121 llylrraarrirspalka 138 + + ++ + s++l++ FUN_002195-T1 103 TYGVSNKPFSLVSQTLNS 120 888888877776666655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (268 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 811 (0.0317479); expected 510.9 (0.02) Passed bias filter: 472 (0.0184772); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2632.95 // Query: FUN_002196-T1 [L=99] Description: FUN_002196 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 671 (0.0262674); expected 510.9 (0.02) Passed bias filter: 554 (0.0216872); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1015.35 // Query: FUN_002197-T1 [L=297] Description: FUN_002197 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-09 36.2 4.6 8.3e-09 36.2 4.6 2.1 2 Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain 0.0011 20.4 0.7 0.0035 18.8 0.7 1.9 1 Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain ------ inclusion threshold ------ 0.036 14.6 0.3 14 6.2 0.0 2.9 3 PH_21 C-Maf-inducing protein PH domain 0.077 13.6 1.5 0.22 12.1 0.1 2.0 2 RelA_AH_RIS RelA/SpoT, AH and RIS domains 0.093 13.6 0.9 0.093 13.6 0.9 2.0 2 MADF_DNA_bdg Alcohol dehydrogenase transcription factor My 4.1 8.3 5.8 0.54 11.1 1.7 1.9 2 Salp15 Salivary protein of 15kDa inhibits CD4+ T cel 6.6 7.4 8.2 17 6.0 4.0 2.3 2 YqfQ YqfQ-like protein Domain annotation for each model (and alignments): >> Myb_DNA-bind_4 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.2 4.6 2.3e-12 8.3e-09 3 88 .. 105 192 .. 104 193 .. 0.87 2 ? -1.1 0.1 1 3.7e+03 6 24 .. 251 268 .. 236 288 .. 0.68 Alignments for each domain: == domain 1 score: 36.2 bits; conditional E-value: 2.3e-12 Myb_DNA-bind_4 3 kWteeetkaLieiwkellelrfqekgkkrnkklweeiaekmaer.gykrspeqckeKwenLkkkYkkekesekgsg...skwpyfeelde 88 +W+++ +++Li+ +++ +++f + gk +k+++++i +++++ k++ eqc +Kw +L+ k k++ ++++++g ++w++ e++ e FUN_002197-T1 105 RWEDSHVRLLISSYSK-FKDLFGR-GKTTKKEVFNKICAEFNAIsDHKVTVEQCMRKWAKLEIKLKEIEDNNNQTGrarKSWKFQEDMTE 192 8***************.6888*99.5666666*********97625799*********************9888775555****999975 PP == domain 2 score: -1.1 bits; conditional E-value: 1 Myb_DNA-bind_4 6 eeetkaLieiwkellelrf 24 +e++++++ ++e ++++ FUN_002197-T1 251 AGEMLEFLQSYSE-KREKV 268 5677777777777.34433 PP >> Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.7 9.5e-07 0.0035 2 71 .. 106 173 .. 105 193 .. 0.85 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 9.5e-07 Myb_DNA-bind_3 2 Wspemekllvdllleqvkkgnriegntfkkeawkeileefnaktgakytkeqlknrlkklrkqyklvkel 71 W++++ +ll+ + + ++ r g+t kke +++i++efna + k+t eq+ +++ kl+ + k +++ FUN_002197-T1 106 WEDSHVRLLISSYSKFKDLFGR--GKTTKKEVFNKICAEFNAISDHKVTVEQCMRKWAKLEIKLKEIEDN 173 8888889998888877777666..89**********************************9998887765 PP >> PH_21 C-Maf-inducing protein PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.61 2.2e+03 80 113 .. 19 55 .. 6 60 .. 0.58 2 ? 6.2 0.0 0.0039 14 16 42 .. 88 114 .. 79 122 .. 0.77 3 ? 4.9 0.1 0.0098 36 23 45 .. 149 171 .. 137 191 .. 0.83 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.61 PH_21 80 lrivvndgslllqannaylrdQwly...Siqwkknvl 113 +v+ + sl + rdQ+l+ S+ w k+++ FUN_002197-T1 19 CVLVTITSSLRVDDVLDSSRDQFLWktmSLPWIKAAH 55 3344444444444455678999874333777877665 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0039 PH_21 16 rhtrtviskilsskflRrWekhhiiLe 42 +++ s s kfl rWe+ h++L FUN_002197-T1 88 QQAGASTSTAESPKFLERWEDSHVRLL 114 5555666677789***********995 PP == domain 3 score: 4.9 bits; conditional E-value: 0.0098 PH_21 23 skilsskflRrWekhhiiLedse 45 +k+ +++R+W k +i+L++ e FUN_002197-T1 149 HKVTVEQCMRKWAKLEIKLKEIE 171 4888899**********998754 PP >> RelA_AH_RIS RelA/SpoT, AH and RIS domains # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.1 5.9e-05 0.22 24 109 .. 74 166 .. 64 203 .. 0.80 2 ? 0.2 0.2 0.26 9.4e+02 97 129 .. 221 253 .. 204 276 .. 0.71 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 5.9e-05 RelA_AH_RIS 24 qyaglGrrileraferagkefseeelkaalerlarkevedllaa.......vGrgelssedvlkavypdykeerakkakpkakeegwfelkka 109 + + +G++i ++a+++ag + s++e ++ler + ++v+ l+ + Grg+ + ++v++++ +++ +k++ ++ w +l+ + FUN_002197-T1 74 ESSFVGEDICAAALQQAGASTSTAESPKFLERWEDSHVRLLISSyskfkdlFGRGKTTKKEVFNKICAEFNAISDHKVTVEQCMRKWAKLEIK 166 55679*****************************999998887644444447*******************8888777777778888887654 PP == domain 2 score: 0.2 bits; conditional E-value: 0.26 RelA_AH_RIS 97 kakeegwfelkkaaglkfrvpgkekeekakkke 129 ++ eeg + ++ ++ k+++p+k++++k+++ e FUN_002197-T1 221 SDGEEGDTDGEEERKKKVKMPRKKRKSKSSAGE 253 446788888888888999999987776654444 PP >> MADF_DNA_bdg Alcohol dehydrogenase transcription factor Myb/SANT-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.9 2.6e-05 0.093 21 81 .. 128 190 .. 118 191 .. 0.81 2 ? -1.5 0.2 1.3 4.8e+03 62 84 .] 235 258 .. 231 258 .. 0.65 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.6e-05 MADF_DNA_bdg 21 nkeakekaweeiaeelgskvs....veeckkkwknLRdqyrrelrkkksesgeskksrwryfeel 81 k+ k++++++i++e+++ + ve+c +kw +L + + e++ ++ ++ ++ +++w++ e++ FUN_002197-T1 128 GKTTKKEVFNKICAEFNAISDhkvtVEQCMRKWAKLEIKLK-EIEDNN-NQTGRARKSWKFQEDM 190 577899999999999975444555599*********99985.565555.69999******99998 PP == domain 2 score: -1.5 bits; conditional E-value: 1.3 MADF_DNA_bdg 62 kkk.sesgeskksrwryfeelsFL 84 kkk +++ +++ks+ + e l+FL FUN_002197-T1 235 KKKvKMPRKKRKSKSSAGEMLEFL 258 333357777778888888888887 PP >> Salp15 Salivary protein of 15kDa inhibits CD4+ T cell activation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 1.7 0.00015 0.54 24 70 .. 96 158 .. 15 190 .. 0.79 2 ? -2.1 0.1 1.9 6.9e+03 25 45 .. 235 255 .. 206 281 .. 0.58 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00015 Salp15 24 e...................niaeklpkligdckkelalklekrCeekskkkkineklvdfknCtf 70 + + k+++l g+ k++ ++ ++k+C e +++i +++v++++C FUN_002197-T1 96 TaespkflerwedshvrlliSSYSKFKDLFGRGKTTKKEVFNKICAE---FNAISDHKVTVEQCMR 158 0334556677777777788888999*********99*********77...**************75 PP == domain 2 score: -2.1 bits; conditional E-value: 1.9 Salp15 25 niaeklpkligdckkelalkl 45 + + k+p+ +++k++ + l FUN_002197-T1 235 KKKVKMPRKKRKSKSSAGEML 255 445555555555554333333 PP >> YqfQ YqfQ-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.038 1.4e+02 82 124 .. 48 96 .. 45 131 .. 0.70 2 ? 6.0 4.0 0.0047 17 93 156 .. 208 270 .. 198 279 .. 0.62 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.038 YqfQ 82 lPalvkiyrslkssddeeteevteseetevs......eteesednkkkk 124 lP + +s + s+ + t+ ++e+ee + + ++ ++ ++ FUN_002197-T1 48 LPWIKAAHSSVEASEKTTTDGTKEAEESSFVgedicaAALQQAGASTST 96 6777777889999999999999999977765444443333333333333 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0047 YqfQ 93 kssddeeteevteseetevseteesednk.kkkpkaeskkkktktkdkkeeeiekeapkrkkvps 156 ss+ ++ ++ +s+++e t+ +e+ k k k + +++k+k+ + ++ e +++ ++kr+kv+ FUN_002197-T1 208 TSSSSNSGTNQCDSDGEEGD-TDGEEERKkKVKMPRKKRKSKS-SAGEMLEFLQSYSEKREKVEA 270 45666677777888877766.5544444304444444444444.445555668888899888865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (297 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1931 (0.0755921); expected 510.9 (0.02) Passed bias filter: 687 (0.0268937); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 2857.97 // Query: FUN_002199-T1 [L=522] Description: FUN_002199 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-28 99.2 0.1 4.9e-28 98.5 0.1 1.3 1 WS_DGAT_C WS/DGAT C-terminal domain 3.3e-07 30.8 0.0 0.00015 22.1 0.0 2.2 2 WS_DGAT_cat Wax ester synthase/diacylglycerol acyltransfera ------ inclusion threshold ------ 0.034 13.3 0.0 0.12 11.6 0.0 1.7 2 Condensation Condensation domain 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 PapA_C Phthiocerol/phthiodiolone dimycocerosyl transfe 0.9 9.7 2.7 1.8 8.8 2.7 1.5 1 DUF7535 Family of unknown function (DUF7535) Domain annotation for each model (and alignments): >> WS_DGAT_C WS/DGAT C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.5 0.1 9.6e-32 4.9e-28 3 144 .. 368 509 .. 366 510 .. 0.95 Alignments for each domain: == domain 1 score: 98.5 bits; conditional E-value: 9.6e-32 WS_DGAT_C 3 NqfglvllpLpvaladplerlrkakasmdrkKrslealltyallelllkllgakvaaalikrllsnttlviSNvpGPreelylaGapvkgiaplvp 98 N f++v+ +L+va++d ++ l ++ka+md+ K s a + + +ll+ ++ ++ ls++++++SNvpGP+ l+++G+++k++ ++ p FUN_002199-T1 368 NLFTFVFPKLAVATDDVVKQLYETKARMDKIKFSGLAWASDIAHLTSQNLLPVFCNFKINSFCLSKASCLLSNVPGPQHMLTVNGSRMKYLTFWPP 463 89**********************************999988888878888888888888888********************************* PP WS_DGAT_C 99 glpgqalnitvlSyagklriglavdkdlipdpqkllddfeealeel 144 +++++++i+++Syag++ +g+ d+ ++pdp ++ld+f +a +e+ FUN_002199-T1 464 NVSNIGISISITSYAGQVIVGVQSDASVLPDPVEILDEFVNAVNEM 509 ******************************************9998 PP >> WS_DGAT_cat Wax ester synthase/diacylglycerol acyltransferase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 3e-08 0.00015 22 149 .. 105 237 .. 89 270 .. 0.73 2 ! 6.8 0.0 0.0014 7.1 241 262 .. 302 323 .. 257 324 .. 0.84 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 3e-08 WS_DGAT_cat 22 alavleppskgagelfvrrlreaieqrleaaprfr.qkvvekplglaapvW.....vededfDldyHvRrvalpaPGgereLlelvsrLasspLDr 111 al +e++ g e+ v+++r+ai +r a + + + ++ +p W ++d+ f ++ Hv ++ P +++eL+ +vs++ ++p FUN_002199-T1 105 ALHCFENK--GSIERGVENFRQAILERMVNAKKANgNLLYPRVRCYLRPGWlqyflRKDQSFKIENHVFKWKGEIPRSRDELATVVSKMSNEPFPE 198 55555555..3333336666666555544433333033333333334455533333789************************************* PP WS_DGAT_cat 112 srPLWevhviEG.leggriAvllkvHHAlvDGvgglell 149 +r +W i+ ++ i v++++ H l+DG + + FUN_002199-T1 199 GRSPWYYCCIPTnFGDNDIVVMFRIKHYLADGTSLSKFT 237 ***********9899*****************9866655 PP == domain 2 score: 6.8 bits; conditional E-value: 0.0014 WS_DGAT_cat 241 aslpLadvkavakalgvtiNDv 262 + ++L+ +k ++ a+g+t+NDv FUN_002199-T1 302 EAIDLQLIKDIKSATGTTVNDV 323 5689999**************9 PP >> Condensation Condensation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.19 9.7e+02 99 148 .. 184 234 .. 152 238 .. 0.63 2 ? 11.6 0.0 2.3e-05 0.12 236 270 .. 305 339 .. 282 342 .. 0.87 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.19 Condensation 99 ieafiqkdlqepfdLekgpLfraal.fkiaenrhllllsvHHiivDGvSlg 148 ++++++k ++epf ++p ++ + +n ++++++ H ++DG Sl+ FUN_002199-T1 184 LATVVSKMSNEPFPEGRSPWYYCCIpTNFGDNDIVVMFRIKHYLADGTSLS 234 5555555566666666666655555234678999999**********9986 PP == domain 2 score: 11.6 bits; conditional E-value: 2.3e-05 Condensation 236 teeklrklakeqgvtlndvllaalgllLskytgqd 270 ++++++ +++g+t+ndvl ++l+l+L +y +++ FUN_002199-T1 305 DLQLIKDIKSATGTTVNDVLTSCLSLALRRYFQRK 339 568899*************************8766 PP >> PapA_C Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 4.3e-05 0.22 26 67 .. 315 358 .. 309 367 .. 0.90 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 4.3e-05 PapA_C 26 aagvsvnglvsgaillAerael..lreedpvplgllypVDlRsr 67 a+g++vn++++ ++lA r+ + e+p +++ +VD+Rsr FUN_002199-T1 315 ATGTTVNDVLTSCLSLALRRYFqrKGIENPDDFTAAVAVDVRSR 358 789******************98555577899***********9 PP >> DUF7535 Family of unknown function (DUF7535) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 2.7 0.00035 1.8 33 51 .. 48 66 .. 44 74 .. 0.76 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.00035 DUF7535 33 flvllvllvPLLPFivivw 51 ++ l+ lvPL+PFi++ FUN_002199-T1 48 SALFLIALVPLIPFIAVLN 66 5677899*******98764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (522 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 737 (0.028851); expected 510.9 (0.02) Passed bias filter: 664 (0.0259933); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 5060.73 // Query: FUN_002200-T1 [L=732] Description: FUN_002200 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6e-91 305.7 1.2 1.2e-90 304.7 1.2 1.5 1 COG2_C COG complex component, COG2, C-terminal 2.8e-23 82.3 2.5 5.2e-21 75.0 1.1 2.8 2 COG2_N COG2 N-terminal 0.00082 19.9 0.2 0.0049 17.4 0.0 2.5 2 VPS51_Exo84_N Vps51/EXO84/COG1 N-terminal ------ inclusion threshold ------ 0.036 14.5 0.2 0.41 11.1 0.0 2.4 2 DUF2120 Uncharacterized protein conserved in archaea ( 0.045 14.7 0.0 0.18 12.8 0.0 2.0 2 DUF772 Transposase domain (DUF772) 1.4 9.7 4.7 7 7.5 0.3 3.4 4 TBCC_N Tubulin-specific chaperone C N-terminal domain Domain annotation for each model (and alignments): >> COG2_C COG complex component, COG2, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 304.7 1.2 2.8e-94 1.2e-90 2 302 .. 389 693 .. 388 694 .. 0.95 Alignments for each domain: == domain 1 score: 304.7 bits; conditional E-value: 2.8e-94 COG2_C 2 kWnLpVYFqLrfqeiagsleealseeklevaeaeassefalkqsealwealercWsedvflpelahrfwkltlqllsRysswlkealnalsasesk 97 +W+LpVYFq+rfqe+a+++e++l++++ + +++s++f + + ++lw +++rcW+++vfl++l+hrfwkltlqllsR s w+ + + a+ + FUN_002200-T1 389 RWSLPVYFQIRFQEMASKFETSLQSPQVCT-AEQDSEQFMTCAVSVLWWCVQRCWQDSVFLQALCHRFWKLTLQLLSRLSVWVRDDMLCAGAK-VT 482 9*************************9876.778899**********************************************9888775543.44 PP COG2_C 98 kessseessaaesasleqlvaliaDiekLeekvpelllesispklssssskelslleealeeslkslesllpklsetivqelvercveaLkqvksi 193 e + ++++a+e++++ lv+l+ D++ L +kvpe++ + i p+l++s++++l+ll+ea+ es+ l++l+p l+ +iv+++v+ ++ L+++k+i FUN_002200-T1 483 AEVTGNTNQATEQEQTYILVYLLKDLDVLLKKVPEFFRQGILPRLRQSNIQDLDLLSEAILESCGVLQQLIPGLEGQIVSQVVNGASHGLDAAKNI 578 5888899999999999******************************************************************************** PP COG2_C 194 prlyRmtnkevPtkpSsYVssilkplkefleeeeaelkeeileewlkevleevterYlelvsevLssvkkteesLrRlkkgrkr......laasst 283 prlyR+tnkevPtk+S++V+++l+ +++fl++++ ++++++++ w++++++++ ++Y ++s+vL+s+k+te+sL Rlk+ rk+ +s++ FUN_002200-T1 579 PRLYRRTNKEVPTKASPFVNNVLRSVRDFLDQNQLYVSQSQRQAWAAAIMQTLLSKYRVITSDVLTSIKRTEDSLMRLKRSRKQlgpgsgGQGSNQ 674 **************************************************************************************9876555555 PP COG2_C 284 assegvsDddKIrlQLllD 302 + + +sDddKIrlQ+ lD FUN_002200-T1 675 EGQCVISDDDKIRLQFTLD 693 666789************9 PP >> COG2_N COG2 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.0 1.1 1.2e-24 5.2e-21 2 71 .. 18 87 .. 17 91 .. 0.96 2 ! 5.5 0.0 0.0059 25 9 47 .. 175 214 .. 170 222 .. 0.83 Alignments for each domain: == domain 1 score: 75.0 bits; conditional E-value: 1.2e-24 COG2_N 2 cFdkreFlapdFdpdaFvselrkhvpLeslredLraylkllkeelvelvnedyedFvslStnLvgleekl 71 F++++F+++ F++d Fv +++ v+L+ l+ +L++ylk+lk +l+el+nedy+dFv+lStnLvg+++++ FUN_002200-T1 18 VFSRSDFMKESFSVDIFVGSCKGNVQLDLLKANLDDYLKSLKHALIELINEDYADFVNLSTNLVGMDKNI 87 69*****************************************************************987 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0059 COG2_N 9 lapdFdpdaFvse.lrkhvpLeslredLraylkllkeelv 47 +a +F++ +F + ++ h +es+r ++a+ + l+++l FUN_002200-T1 175 MASEFNQLQFYVTqSQGHPLVESIRGRIAAITSTLQKKLE 214 6789***998777355666679***************996 PP >> VPS51_Exo84_N Vps51/EXO84/COG1 N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 1.1e-06 0.0049 4 85 .. 27 105 .. 24 107 .. 0.86 2 ? -2.4 0.0 1.8 7.6e+03 52 68 .. 134 150 .. 133 153 .. 0.82 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 1.1e-06 VPS51_Exo84_N 4 psfdaqryvsellskstleellqlesslrseieeldeelkqlVydnYrdlikaadtiskmksemeqleqklselkqalekla 85 +sf+++ +v s + +l+ l+++l + l++ l +l+++ Y d+++ +++++ m +++ +l+ l +lk+++ ++ FUN_002200-T1 27 ESFSVDIFVG---SCKGNVQLDLLKANLDDYLKSLKHALIELINEDYADFVNLSTNLVGMDKNIFSLSVPLGQLKEEVLLIK 105 6777777777...233346899999999999********************************************9987666 PP == domain 2 score: -2.4 bits; conditional E-value: 1.8 VPS51_Exo84_N 52 dlikaadtiskmkseme 68 +l+++++ ++k+++ m+ FUN_002200-T1 134 HLLNITKSLEKIERLMQ 150 78999999999998875 PP >> DUF2120 Uncharacterized protein conserved in archaea (DUF2120) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 9.7e-05 0.41 28 82 .. 34 88 .. 19 117 .. 0.85 2 ? 0.4 0.0 0.2 8.5e+02 34 72 .. 161 199 .. 117 221 .. 0.66 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 9.7e-05 DUF2120 28 vrgvsrkkekaeeleskleellkkleaeevdlvseeakkliakldeqiretveve 82 g ++++ +++ l+ +l++ lk l+++ ++l++e+ +++++ + + ++++ FUN_002200-T1 34 FVGSCKGNVQLDLLKANLDDYLKSLKHALIELINEDYADFVNLSTNLVGMDKNIF 88 5699**************************************9998888877776 PP == domain 2 score: 0.4 bits; conditional E-value: 0.2 DUF2120 34 kkekaeeleskleellkkleaeevdlvseeakkliakld 72 k+ ++++ ++ +e++ + ++ ++ +++ +++ l++++ FUN_002200-T1 161 KELDRDDGSQLIERMASEFNQLQFYVTQSQGHPLVESIR 199 344455555555555555555555555555555555555 PP >> DUF772 Transposase domain (DUF772) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 4.3e-05 0.18 26 79 .. 335 388 .. 322 394 .. 0.86 2 ? -3.6 0.0 5.8 2.5e+04 10 26 .. 598 614 .. 593 628 .. 0.72 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 4.3e-05 DUF772 26 eseleklysktGrp.ayppelmlkilllqylyglrsdrqleealrenlsfrwflg 79 +++ + ++ G p +++ + m + ++ ++gl +++ +e+lr +sf+ flg FUN_002200-T1 335 KTRFGSIFA-PGNPdSFHQKYMTTVWFINKFEGLCGSKASVERLRSHPSFMSFLG 388 456666666.59999***************************************9 PP == domain 2 score: -3.6 bits; conditional E-value: 5.8 DUF772 10 dhplrkldklvdweele 26 ++ lr +++++d+++l+ FUN_002200-T1 598 NNVLRSVRDFLDQNQLY 614 67888999999875554 PP >> TBCC_N Tubulin-specific chaperone C N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.0 3.9 1.7e+04 35 71 .. 21 58 .. 12 60 .. 0.73 2 ? 4.3 0.1 0.016 70 29 81 .. 99 152 .. 96 155 .. 0.88 3 ? 7.5 0.3 0.0017 7 39 82 .. 139 190 .. 137 219 .. 0.83 4 ? -0.6 0.1 0.55 2.3e+03 33 62 .. 395 424 .. 393 433 .. 0.75 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 3.9 TBCC_N 35 lsaFneekaeieellsqar.sadkeklkekldeiseei 71 s F +e+ +++ + +++ + + + lk++ld++ +++ FUN_002200-T1 21 RSDFMKESFSVDIFVGSCKgNVQLDLLKANLDDYLKSL 58 56788888888888888888888888888888876665 PP == domain 2 score: 4.3 bits; conditional E-value: 0.016 TBCC_N 29 ekvdaFlsaFneekaeieellsqar.sadkeklkekldeiseeiqeLqkllaes 81 e+v ++s ++ + ++ie l++ +k+ ++l +i+++++++++l+ s FUN_002200-T1 99 EEVLLIKSDLDGTVNAIETKLDERAlLRKKKMCMQHLLNITKSLEKIERLMQGS 152 667778889999999*******99989999999****************98766 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0017 TBCC_N 39 neekaeieellsqar........sadkeklkekldeiseeiqeLqkllaess 82 +++ ++ie l++++r + d+++ ++ ++ +++e+++Lq ++++s FUN_002200-T1 139 TKSLEKIERLMQGSRisqggpskELDRDDGSQLIERMASEFNQLQFYVTQSQ 190 5666788888888888889999999************************996 PP == domain 4 score: -0.6 bits; conditional E-value: 0.55 TBCC_N 33 aFlsaFneekaeieellsqarsadkeklke 62 +F+ +F+e + + e +l++ + +e+ +e FUN_002200-T1 395 YFQIRFQEMASKFETSLQSPQVCTAEQDSE 424 7999*************9988444444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (732 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 945 (0.0369935); expected 510.9 (0.02) Passed bias filter: 677 (0.0265023); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.37u 0.41s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 6976.86 // Query: FUN_002200-T2 [L=603] Description: FUN_002200 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-91 306.1 1.2 7.4e-91 305.4 1.2 1.4 1 COG2_C COG complex component, COG2, C-terminal ------ inclusion threshold ------ 0.035 15.1 0.0 0.14 13.2 0.0 2.0 2 DUF772 Transposase domain (DUF772) Domain annotation for each model (and alignments): >> COG2_C COG complex component, COG2, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 305.4 1.2 5.8e-95 7.4e-91 2 302 .. 260 564 .. 259 565 .. 0.95 Alignments for each domain: == domain 1 score: 305.4 bits; conditional E-value: 5.8e-95 COG2_C 2 kWnLpVYFqLrfqeiagsleealseeklevaeaeassefalkqsealwealercWsedvflpelahrfwkltlqllsRysswlkealnalsasesk 97 +W+LpVYFq+rfqe+a+++e++l++++ + +++s++f + + ++lw +++rcW+++vfl++l+hrfwkltlqllsR s w+ + + a+ + FUN_002200-T2 260 RWSLPVYFQIRFQEMASKFETSLQSPQVCT-AEQDSEQFMTCAVSVLWWCVQRCWQDSVFLQALCHRFWKLTLQLLSRLSVWVRDDMLCAGAK-VT 353 9*************************9876.778899**********************************************9888775543.44 PP COG2_C 98 kessseessaaesasleqlvaliaDiekLeekvpelllesispklssssskelslleealeeslkslesllpklsetivqelvercveaLkqvksi 193 e + ++++a+e++++ lv+l+ D++ L +kvpe++ + i p+l++s++++l+ll+ea+ es+ l++l+p l+ +iv+++v+ ++ L+++k+i FUN_002200-T2 354 AEVTGNTNQATEQEQTYILVYLLKDLDVLLKKVPEFFRQGILPRLRQSNIQDLDLLSEAILESCGVLQQLIPGLEGQIVSQVVNGASHGLDAAKNI 449 5888899999999999******************************************************************************** PP COG2_C 194 prlyRmtnkevPtkpSsYVssilkplkefleeeeaelkeeileewlkevleevterYlelvsevLssvkkteesLrRlkkgrkr......laasst 283 prlyR+tnkevPtk+S++V+++l+ +++fl++++ ++++++++ w++++++++ ++Y ++s+vL+s+k+te+sL Rlk+ rk+ +s++ FUN_002200-T2 450 PRLYRRTNKEVPTKASPFVNNVLRSVRDFLDQNQLYVSQSQRQAWAAAIMQTLLSKYRVITSDVLTSIKRTEDSLMRLKRSRKQlgpgsgGQGSNQ 545 **************************************************************************************9876555555 PP COG2_C 284 assegvsDddKIrlQLllD 302 + + +sDddKIrlQ+ lD FUN_002200-T2 546 EGQCVISDDDKIRLQFTLD 564 666789************9 PP >> DUF772 Transposase domain (DUF772) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 1.1e-05 0.14 26 79 .. 206 259 .. 192 265 .. 0.86 2 ? -3.1 0.0 1.3 1.6e+04 10 26 .. 469 485 .. 463 501 .. 0.71 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1.1e-05 DUF772 26 eseleklysktGrp.ayppelmlkilllqylyglrsdrqleealrenlsfrwflg 79 +++ + ++ G p +++ + m + ++ ++gl +++ +e+lr +sf+ flg FUN_002200-T2 206 KTRFGSIFA-PGNPdSFHQKYMTTVWFINKFEGLCGSKASVERLRSHPSFMSFLG 259 456666666.59999***************************************9 PP == domain 2 score: -3.1 bits; conditional E-value: 1.3 DUF772 10 dhplrkldklvdweele 26 ++ lr +++++d+++l+ FUN_002200-T2 469 NNVLRSVRDFLDQNQLY 485 78889999999975554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (603 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 926 (0.0362498); expected 510.9 (0.02) Passed bias filter: 718 (0.0281073); expected 510.9 (0.02) Passed Vit filter: 51 (0.00199648); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.35u 0.41s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 5876.02 // Query: FUN_002201-T1 [L=175] Description: FUN_002201 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-13 50.3 1.5 8e-06 25.7 0.2 2.1 2 p31comet Mad1 and Cdc20-bound-Mad2 binding Domain annotation for each model (and alignments): >> p31comet Mad1 and Cdc20-bound-Mad2 binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.2 3.2e-10 8e-06 44 135 .. 4 99 .. 1 108 [. 0.77 2 ! 25.0 0.1 5.2e-10 1.3e-05 207 264 .. 101 169 .. 98 170 .. 0.73 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 3.2e-10 p31comet 44 dslvpvvfpgpvsqegccqftcellkhilyqrqqlplpyeqlkhfyrksspq...aedmlkkk.araiteassrkcqqalaelesvlshledlfar 135 + v v++ +++ ++ ++ ++lyqrqqlplp ++lk + +++ + ed+ k+ + ++ +k + ++l++++ h+++lf+ FUN_002201-T1 4 EVQVEVILSEEINRATNSRLLSSFIEYLLYQRQQLPLPVHELKRIVEEQGKNydsLEDTRKHVvPSRPLSVELKKASKVNQDLQCLFDHINQLFSV 99 556889999999999999**************************98865544111455444321334456778899999999***********975 PP == domain 2 score: 25.0 bits; conditional E-value: 5.2e-10 p31comet 207 qghrdcgedwfrpklnyrvpsrghkltvtl..scgrpsipataw......e...dyiwfqapvtlkgfr 264 + r +wfrpk ++ p+rg +tl c +i++t++ + d +wfqap+ ++g+r FUN_002201-T1 101 EASRTSVVEWFRPKPTFKPPHRGRCCKITLrsLCKAQNIEDTTShgipyeQdyrDLLWFQAPIIIRGYR 169 566777889**************8666666226999999987642222222222679**********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (175 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 689 (0.026972); expected 510.9 (0.02) Passed bias filter: 569 (0.0222744); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1762.23 // Query: FUN_002202-T1 [L=83] Description: FUN_002202 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (83 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 448 (0.0175377); expected 510.9 (0.02) Passed bias filter: 341 (0.013349); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.38s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 883.18 // Query: FUN_002203-T1 [L=223] Description: FUN_002203 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-22 78.9 0.0 9.3e-22 78.4 0.0 1.2 1 PP2C Protein phosphatase 2C Domain annotation for each model (and alignments): >> PP2C Protein phosphatase 2C # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.4 0.0 3.6e-26 9.3e-22 84 177 .. 9 101 .. 1 107 [. 0.88 Alignments for each domain: == domain 1 score: 78.4 bits; conditional E-value: 3.6e-26 PP2C 84 tdeelksdsantedlksGstavvalisgqk.lyvAnvGDsravLcrngnaikaltkdHkpsdedErrRieeaggfvsr..egrvngvLavsRalGD 176 ++ e+++ ++ l +G+ta+v+l ++ + l vA vGDs ++cr g+ +lt+ H+p++e+E +Ri++ g++++ +vng La++R++GD FUN_002203-T1 9 ARPETNQ---RNTVLLCGTTATVVLSRDGTdLAVARVGDSGSLICRLGEPL-PLTNPHHPAREEEEQRIKSFSGWIDWsiGAKVNGRLAMTRSVGD 100 3333333...34689**********999888********************.***************************99*************** PP PP2C 177 f 177 f FUN_002203-T1 101 F 101 9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (223 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 491 (0.019221); expected 510.9 (0.02) Passed bias filter: 459 (0.0179683); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2272.98 // Query: FUN_002206-T1 [L=1530] Description: FUN_002206 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-10 41.4 0.0 3.8e-10 40.2 0.0 1.7 1 CIDE-N CIDE-N domain 6.4e-10 39.6 0.2 9.8e-09 35.8 0.0 3.0 2 NCD2 NAB conserved region 2 (NCD2) 0.0066 16.9 14.9 0.0066 16.9 14.9 3.7 3 PHD PHD-finger ------ inclusion threshold ------ 0.041 14.6 0.4 0.6 10.9 0.0 2.4 2 DUF8186_C Domain of unknown function (DUF8186) C-terminal do 0.18 12.2 0.2 1.4 9.3 0.0 2.4 3 MutS_V MutS domain V Domain annotation for each model (and alignments): >> CIDE-N CIDE-N domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.2 0.0 7.4e-14 3.8e-10 4 75 .. 4 74 .. 2 75 .. 0.95 Alignments for each domain: == domain 1 score: 40.2 bits; conditional E-value: 7.4e-14 CIDE-N 4 fkvrdvdrskkkGvaassleeLlkkacekLklsseevtlvLeeDGTevddeeYFqtLpdnTelmllekgekw 75 fk +dv+r k+k+v+a+ +ee+++ a++kL+++s+evt+ e DGTe+ d + F+ +++ + l++ +e+w FUN_002206-T1 4 FKAWDVKRVKRKSVVATHFEEFVTGAKRKLGIDSDEVTIYTEADGTEI-DVDSFSEIEAGSILICAVGDETW 74 899*********************************************.5777899*********9999999 PP >> NCD2 NAB conserved region 2 (NCD2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.8 0.0 1.9e-12 9.8e-09 72 125 .] 156 209 .. 149 209 .. 0.96 2 ? -0.7 0.1 0.39 2e+03 11 58 .. 869 916 .. 860 930 .. 0.74 Alignments for each domain: == domain 1 score: 35.8 bits; conditional E-value: 1.9e-12 NCD2 72 eekqLtlhevtvneaaaqlCkkdpaLltrRdeLfsLaRqvvrdagykyskkksr 125 ++k+L+ + +vn aa lC++d++Ll+ R +Lf L+R+ v+d gy+++k+ksr FUN_002206-T1 156 KGKPLSNYQQAVNKAALELCQQDHSLLLDRGKLFELSRKKVKDDGYEFAKGKSR 209 689**********************************************99886 PP == domain 2 score: -0.7 bits; conditional E-value: 0.39 NCD2 11 aesaerlvktlpkldpkllklkkklakeveeilemseedprreeeirk 58 ++ ++ +++ ++ ++ lk+k +++++++l+ ++ r ee+ k FUN_002206-T1 869 KAVRRKSRREFVRQMTERRLLKRKRSRKLGRVLRNYPDIGRTVEEFVK 916 333344445666666677788999999999999998888888888765 PP >> PHD PHD-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 1.4 0.7 3.6e+03 19 30 .. 449 460 .. 447 468 .. 0.86 2 ? -1.3 1.1 0.63 3.2e+03 13 30 .. 1312 1328 .. 1307 1336 .. 0.72 3 ! 16.9 14.9 1.3e-06 0.0066 1 47 [] 1474 1524 .. 1474 1524 .. 0.79 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.7 PHD 19 CkkwfHlkClkp 30 C++ +H+ Cl+ FUN_002206-T1 449 CSTEHHQPCLEC 460 999******986 PP == domain 2 score: -1.3 bits; conditional E-value: 0.63 PHD 13 lvlCdgCkkwfHlkClkp 30 lv+C + k++ H++C + FUN_002206-T1 1312 LVCCYE-KDCIHPECQRG 1328 566665.88999999765 PP == domain 3 score: 16.9 bits; conditional E-value: 1.3e-06 PHD 1 CkvCkk.....sdedeelvlCdgCkkwfHlkClkpplekeelpegewlCpeC 47 C C + + + +++ Cd+C+ w+H++C++++++ ++ +w C++C FUN_002206-T1 1474 CMTCLQeepplNVKVVHWIGCDKCQAWHHQFCVGFTDSVCADD-VDWKCNHC 1524 666766555555566789******************9955554.4******* PP >> DUF8186_C Domain of unknown function (DUF8186) C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.2 0.17 8.5e+02 22 64 .. 40 88 .. 38 107 .. 0.76 2 ? 10.9 0.0 0.00012 0.6 50 80 .. 979 1009 .. 968 1014 .. 0.88 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.17 DUF8186_C 22 velrdaetgepialae....rdgyvtva..gqrvetnasGvatvtlerp 64 v++ ++ g+ i++++ ++g++ + g++ + a+G+at+t++ FUN_002206-T1 40 VTIYTEADGTEIDVDSfseiEAGSILICavGDETWVPAHGTATTTVSTV 88 56666677888888888888888888765578888899********765 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00012 DUF8186_C 50 etnasGvatvtlerpeglvtarYePgsWwrt 80 n +Gva vt +r+ + +t rY+P + w++ FUN_002206-T1 979 SQNYKGVARVTCRRTRKGFTIRYNPDQHWSS 1009 67899*********************99975 PP >> MutS_V MutS domain V # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 0.36 1.9e+03 108 141 .. 10 43 .. 7 57 .. 0.77 2 ? 9.3 0.0 0.00028 1.4 111 167 .. 578 637 .. 565 642 .. 0.78 3 ? -4.2 0.1 4 2e+04 108 140 .. 671 703 .. 668 722 .. 0.72 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.36 MutS_V 108 ekikaktlfatHyheltkleekleavknlhlavk 141 +++k k+++atH++e+ + ++++ + + ++++ FUN_002206-T1 10 KRVKRKSVVATHFEEFVTGAKRKLGIDSDEVTIY 43 56788999*******9988888777766666555 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00028 MutS_V 111 kaktlfatHyhel...tkleekleavknlhlavkeeeeeivflykvkkgaaeksyGikva 167 ka l +t +l l++++e+v+++ ++ke +e+i f+ ++k++a +s+Gi+v FUN_002206-T1 578 KASGLSSTKLRNLygfQDLTARQERVESAMEKAKEIRESIEFVAQIKENAILRSFGISVE 637 555666666655522135566777899999999999*********************996 PP == domain 3 score: -4.2 bits; conditional E-value: 4 MutS_V 108 ekikaktlfatHyheltkleekleavknlhlav 140 ++++a +tH ++l + + +++v+++ ++ FUN_002206-T1 671 KTNQAGEACSTHEFSLPEDPNLCKQVTETVQTC 703 566777778999999999999998888654444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1530 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2280 (0.0892543); expected 510.9 (0.02) Passed bias filter: 619 (0.0242317); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.54u 0.39s 00:00:00.93 Elapsed: 00:00:00.42 # Mc/sec: 14563.96 // Query: FUN_002207-T1 [L=135] Description: FUN_002207 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.55 11.2 10.6 0.32 11.9 0.8 2.9 3 DUF2554 Protein of unknown function (DUF2554) 7.8 6.6 8.2 11 6.1 0.7 2.9 3 DNA_ligase_A_M ATP dependent DNA ligase domain Domain annotation for each model (and alignments): >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 1.9 0.0017 22 36 64 .. 27 55 .. 8 59 .. 0.81 2 ? 11.9 0.8 2.5e-05 0.32 37 64 .. 50 77 .. 45 80 .. 0.88 3 ? 9.0 1.2 0.0002 2.6 39 72 .. 63 99 .. 56 104 .. 0.77 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0017 DUF2554 36 dhqlrheadsdelravaeesaeGlrehfy 64 + ++ he de+r e ++G+r + FUN_002207-T1 27 GVRVDHEKKRDEVRVHHERKSDGVRVDHE 55 55678********************8775 PP == domain 2 score: 11.9 bits; conditional E-value: 2.5e-05 DUF2554 37 hqlrheadsdelravaeesaeGlrehfy 64 ++ he sd +r+ e+ +eG+r h+ FUN_002207-T1 50 VRVDHEKKSDGVRTDHEKKSEGVRVHHE 77 5678**********************96 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0002 DUF2554 39 lrheadsdelravaeesaeGlrehfy...wqksrkpe 72 he s+ +r e+ ++G+r h++ w ks e FUN_002207-T1 63 TDHEKKSEGVRVHHEKRSDGVRFHHQkegWGKSSPKE 99 5699999999999999999999999655577876555 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.7 0.0009 11 13 44 .. 10 41 .. 2 43 .. 0.81 2 ? 3.8 0.2 0.0044 56 23 43 .. 42 62 .. 40 63 .. 0.85 3 ? 1.4 0.5 0.024 3.1e+02 25 40 .. 66 81 .. 53 91 .. 0.54 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0009 DNA_ligase_A_M 13 alkklegkafivEiKyDGeRaqvhkegdevkl 44 +k +g +++ K DG+R+ +k++dev++ FUN_002207-T1 10 HQNKSDGVTVYHKRKRDGVRVDHEKKRDEVRV 41 5567778889999***************9985 PP == domain 2 score: 3.8 bits; conditional E-value: 0.0044 DNA_ligase_A_M 23 ivEiKyDGeRaqvhkegdevk 43 + E K DG+R+ +k++d v+ FUN_002207-T1 42 HHERKSDGVRVDHEKKSDGVR 62 5799********999988875 PP == domain 3 score: 1.4 bits; conditional E-value: 0.024 DNA_ligase_A_M 25 EiKyDGeRaqvhkegd 40 E K +G+R+ +k +d FUN_002207-T1 66 EKKSEGVRVHHEKRSD 81 4455555555555544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (135 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 672 (0.0263065); expected 510.9 (0.02) Passed bias filter: 279 (0.0109219); expected 510.9 (0.02) Passed Vit filter: 28 (0.0010961); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1379.17 // Query: FUN_002208-T1 [L=104] Description: FUN_002208 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0056 17.5 10.4 0.29 12.1 2.5 3.0 3 DUF2554 Protein of unknown function (DUF2554) ------ inclusion threshold ------ 0.035 14.5 2.5 6.5 7.3 0.2 2.8 3 DUF7538 Family of unknown function (DUF7538) 0.062 14.0 0.9 0.9 10.3 0.4 2.1 2 SPP1_Dit Siphovirus-type tail component, C-terminal do 0.089 13.2 2.2 0.11 12.8 2.2 1.3 1 DA_C Diels-Alderase, C-terminal domain 0.12 11.2 0.0 0.14 10.9 0.0 1.2 1 Gp58 gp58-like protein 0.21 12.5 6.1 0.29 12.0 6.1 1.2 1 BT_MCC_alpha Methylcrotonyl-CoA carboxylase, alpha-subunit 0.28 12.4 0.8 20 6.5 0.0 2.4 3 Chordopox_G3 Chordopoxvirus G3 protein 0.41 11.1 2.8 23 5.5 0.1 3.0 4 ComGE Competence system putative prepilin ComGE 0.49 10.4 2.2 15 5.5 0.1 2.1 2 DUF1444 Protein of unknown function (DUF1444) 0.6 10.7 6.8 40 4.9 0.7 4.5 5 Tower Tower 1.4 10.2 5.5 11 7.4 5.5 2.1 1 DUF1764 Eukaryotic protein of unknown function (DUF17 1.6 8.9 6.4 18 5.4 0.3 3.0 2 DNA_ligase_A_M ATP dependent DNA ligase domain 1.7 8.3 7.8 6.5 6.4 1.6 2.1 2 DUF632 Protein of unknown function (DUF632) 1.8 9.2 5.6 5.4 7.7 5.5 1.7 1 PCC_BT Propionyl-coenzyme A carboxylase BT domain Domain annotation for each model (and alignments): >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.0 0.5 0.0059 11 38 67 .. 8 37 .. 3 43 .. 0.84 2 ? 5.5 0.1 0.018 32 39 63 .. 42 66 .. 37 69 .. 0.85 3 ! 12.1 2.5 0.00016 0.29 38 68 .. 63 93 .. 46 101 .. 0.72 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0059 DUF2554 38 qlrheadsdelravaeesaeGlrehfywqk 67 ++ h+ sd + e+ ++G+r h+ + FUN_002208-T1 8 RVHHKKKSDRVTVDHEKKSDGVRVHHEKKS 37 678999*******************98655 PP == domain 2 score: 5.5 bits; conditional E-value: 0.018 DUF2554 39 lrheadsdelravaeesaeGlrehf 63 + he sd +r e ++G+r + FUN_002208-T1 42 VDHEKKSDGVRVYHERQSDGVRVEY 66 569999*********9999999765 PP == domain 3 score: 12.1 bits; conditional E-value: 0.00016 DUF2554 38 qlrheadsdelravaeesaeGlrehfywqks 68 ++ +e sd +r e +eGlr h+ ++ FUN_002208-T1 63 RVEYEKKSDGVRVHHETKSEGLRVHHEKERW 93 4567788888888888888888888865444 PP >> DUF7538 Family of unknown function (DUF7538) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.0 0.01 19 13 39 .. 3 29 .. 1 29 [. 0.90 2 ? 7.3 0.2 0.0036 6.5 17 48 .. 29 61 .. 26 65 .. 0.84 3 ? 3.9 0.2 0.04 73 16 39 .. 50 73 .. 45 87 .. 0.76 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.01 DUF7538 13 eeaaarvhyeGaddrysieyyepsecv 39 e+ rvh++ +dr ++++ ++s+ v FUN_002208-T1 3 EGNGVRVHHKKKSDRVTVDHEKKSDGV 29 67889***************9999876 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0036 DUF7538 17 arvhyeGaddrysieyyepsecv.lywkvkgdg 48 rvh+e +dr ++++ ++s+ v +y + ++dg FUN_002208-T1 29 VRVHHEKKSDRVTVDHEKKSDGVrVYHERQSDG 61 6********************995676666665 PP == domain 3 score: 3.9 bits; conditional E-value: 0.04 DUF7538 16 aarvhyeGaddrysieyyepsecv 39 rv++e ++d +ey ++s+ v FUN_002208-T1 50 GVRVYHERQSDGVRVEYEKKSDGV 73 568999999999999999999987 PP >> SPP1_Dit Siphovirus-type tail component, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.4 0.00049 0.9 11 52 .. 8 48 .. 5 59 .. 0.86 2 ? 1.5 0.0 0.28 5e+02 11 35 .. 63 87 .. 57 92 .. 0.59 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00049 SPP1_Dit 11 tvtftaaasefklenqeggkfirvnytfsagdvlvIdcekrk 52 +v+ +++++++++ ++++++ +rv+++ ++d++++d ek++ FUN_002208-T1 8 RVHHKKKSDRVTVDHEKKSDGVRVHHEK-KSDRVTVDHEKKS 48 5677888999*************99986.99******88875 PP == domain 2 score: 1.5 bits; conditional E-value: 0.28 SPP1_Dit 11 tvtftaaasefklenqeggkfirvn 35 +v+ +++++ +++ ++++++ +rv+ FUN_002208-T1 63 RVEYEKKSDGVRVHHETKSEGLRVH 87 4455555555666666666666655 PP >> DA_C Diels-Alderase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 2.2 6.3e-05 0.11 58 126 .. 32 96 .. 5 104 .] 0.61 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 6.3e-05 DA_C 58 vvsktedsvvlekavdgekvakekvkegegvtGafrdkntGyvlefvspeegkrWrFevrHkrawwsmp 126 ++k++d v+++++ +++ v + ++++++gv+ +++ k+ G +++ ++eg +v+H++ w+++ FUN_002208-T1 32 HHEKKSDRVTVDHEKKSDGVRVYHERQSDGVRVEYEKKSDGVRVHHETKSEG----LRVHHEKERWRES 96 2345555666666666666777777888888888888888888877665555....4566666666655 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 7.7e-05 0.14 198 256 .. 28 86 .. 5 93 .. 0.73 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 7.7e-05 Gp58 198 gLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveleskisGlqs 256 g+ +++++ +++ + s+G +e + d++r e+ + + G+rv e+k Gl+ FUN_002208-T1 28 GVRVHHEKKSDRVTVDHEKKSDGVRVYHERQSDGVRVEYEKKSDGVRVHHETKSEGLRV 86 55555555566666666777888777778888999999999999999999999999885 PP >> BT_MCC_alpha Methylcrotonyl-CoA carboxylase, alpha-subunit, BT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 6.1 0.00016 0.29 31 112 .. 6 94 .. 2 97 .. 0.71 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00016 BT_MCC_alpha 31 GWRlgg.paptrlrlraggreveVrvrgtaagaevrvgdge.p.avsa..rldgdrltltldgvrrryavard..gdtlwlgrdgrawa 112 G R+++ + r++++++ +++ Vrv+ ++++ +v+v++++ + v++ ++++d ++++++ + ++v+++ + l +++++++w+ FUN_002208-T1 6 GVRVHHkKKSDRVTVDHEKKSDGVRVHHEKKSDRVTVDHEKkSdGVRVyhERQSDGVRVEYEKKSDGVRVHHEtkSEGLRVHHEKERWR 94 66886634566788888888899999987777899996554434444444777889999999999988888541144688888888875 PP >> Chordopox_G3 Chordopoxvirus G3 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.1 0.28 5.2e+02 67 92 .. 7 32 .. 4 39 .. 0.71 2 ? 4.0 0.1 0.065 1.2e+02 63 92 .. 25 54 .. 18 59 .. 0.78 3 ? 6.5 0.0 0.011 20 63 96 .. 58 91 .. 53 98 .. 0.88 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.28 Chordopox_G3 67 viltydartgtvtvavkgkkyifrld 92 v++ ++++++vtv++++k+ r+ FUN_002208-T1 7 VRVHHKKKSDRVTVDHEKKSDGVRVH 32 56777788888998888887655554 PP == domain 2 score: 4.0 bits; conditional E-value: 0.065 Chordopox_G3 63 isdqviltydartgtvtvavkgkkyifrld 92 sd v++ ++++++vtv++++k+ r++ FUN_002208-T1 25 KSDGVRVHHEKKSDRVTVDHEKKSDGVRVY 54 5788999999*********99998766665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.011 Chordopox_G3 63 isdqviltydartgtvtvavkgkkyifrlddedd 96 +sd v++ y+++++ v+v+++ k+ +r+ +e++ FUN_002208-T1 58 QSDGVRVEYEKKSDGVRVHHETKSEGLRVHHEKE 91 68899*******************9999998877 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.1 0.013 23 57 77 .. 5 25 .. 3 26 .. 0.93 2 ? 2.5 0.1 0.11 2e+02 57 77 .. 27 47 .. 25 53 .. 0.90 3 ? 2.0 0.0 0.15 2.7e+02 57 77 .. 60 80 .. 52 86 .. 0.88 4 ? 0.2 0.0 0.56 1e+03 57 77 .. 71 91 .. 66 92 .. 0.82 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.013 ComGE 57 NGvevtvkenqeelivlesgk 77 NGv v+ k+++++++v +++k FUN_002208-T1 5 NGVRVHHKKKSDRVTVDHEKK 25 9****************9987 PP == domain 2 score: 2.5 bits; conditional E-value: 0.11 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v+ ++++++++v +++k FUN_002208-T1 27 DGVRVHHEKKSDRVTVDHEKK 47 6999************99987 PP == domain 3 score: 2.0 bits; conditional E-value: 0.15 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v+ +++++++ v ++ k FUN_002208-T1 60 DGVRVEYEKKSDGVRVHHETK 80 6999************99876 PP == domain 4 score: 0.2 bits; conditional E-value: 0.56 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v+ + ++e+l v ++++ FUN_002208-T1 71 DGVRVHHETKSEGLRVHHEKE 91 689999999999999988865 PP >> DUF1444 Protein of unknown function (DUF1444) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.5 0.022 40 11 44 .. 10 43 .. 6 48 .. 0.80 2 ? 5.5 0.1 0.0081 15 15 44 .. 58 87 .. 47 95 .. 0.82 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.022 DUF1444 11 eeklkeeevtlkfdreedtlriedkktkkgvtik 44 ++k k++ vt+ +++++d +r++++k+ vt++ FUN_002208-T1 10 HHKKKSDRVTVDHEKKSDGVRVHHEKKSDRVTVD 43 5566778889999999999999999999999886 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0081 DUF1444 15 keeevtlkfdreedtlriedkktkkgvtik 44 +++ v++++++++d +r++++++ +g+ ++ FUN_002208-T1 58 QSDGVRVEYEKKSDGVRVHHETKSEGLRVH 87 667889999999999999999999998775 PP >> Tower Tower # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.1 0.11 2e+02 2 10 .. 23 31 .. 22 39 .. 0.87 2 ? -1.2 0.0 1.8 3.3e+03 2 10 .. 34 42 .. 33 42 .. 0.83 3 ? 3.0 0.0 0.083 1.5e+02 2 11 .. 45 54 .. 44 56 .. 0.89 4 ? -1.7 0.0 2.5 4.5e+03 2 10 .. 56 64 .. 55 64 .. 0.84 5 ? 4.9 0.7 0.022 40 2 35 .. 67 97 .. 66 100 .. 0.72 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.11 Tower 2 EKksdGvfv 10 EKksdGv v FUN_002208-T1 23 EKKSDGVRV 31 9*****977 PP == domain 2 score: -1.2 bits; conditional E-value: 1.8 Tower 2 EKksdGvfv 10 EKksd v+v FUN_002208-T1 34 EKKSDRVTV 42 999998876 PP == domain 3 score: 3.0 bits; conditional E-value: 0.083 Tower 2 EKksdGvfvF 11 EKksdGv v+ FUN_002208-T1 45 EKKSDGVRVY 54 9*****9885 PP == domain 4 score: -1.7 bits; conditional E-value: 2.5 Tower 2 EKksdGvfv 10 E++sdGv v FUN_002208-T1 56 ERQSDGVRV 64 999**9865 PP == domain 5 score: 4.9 bits; conditional E-value: 0.022 Tower 2 EKksdGvfvFRneRaEerEArkyaeaqqKklEaL 35 EKksdGv v + E + + ++++ +E L FUN_002208-T1 67 EKKSDGVRVHHETK---SEGLRVHHEKERWRESL 97 99****98854444...36777777777777776 PP >> DUF1764 Eukaryotic protein of unknown function (DUF1764) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 5.5 0.0063 11 33 76 .. 13 56 .. 3 96 .. 0.55 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0063 DUF1764 33 kekkkkkkkkkkkkkkkeeeekfedskekkkrkktedGlpvYte 76 k+ + + +++kk++ + +++ ++++ + ++k++dG++vY+e FUN_002208-T1 13 KKSDRVTVDHEKKSDGVRVHHEKKSDRVTVDHEKKSDGVRVYHE 56 22222333333333333333333333445556666666666665 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.3 0.01 18 23 43 .. 21 41 .. 7 43 .. 0.81 2 ? 4.7 1.1 0.017 30 22 43 .. 53 74 .. 42 92 .. 0.61 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.01 DNA_ligase_A_M 23 ivEiKyDGeRaqvhkegdevk 43 E K DG+R+ +k++d+v+ FUN_002208-T1 21 DHEKKSDGVRVHHEKKSDRVT 41 4699***********999986 PP == domain 2 score: 4.7 bits; conditional E-value: 0.017 DNA_ligase_A_M 22 fivEiKyDGeRaqvhkegdevk 43 ++ E DG+R++ +k++d v+ FUN_002208-T1 53 VYHERQSDGVRVEYEKKSDGVR 74 4445555555555555555444 PP >> DUF632 Protein of unknown function (DUF632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 1.6 0.0036 6.5 108 142 .. 13 47 .. 10 50 .. 0.93 2 ? 5.6 0.4 0.0065 12 108 144 .. 57 93 .. 51 99 .. 0.75 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0036 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++++ +++ekk+ r + ek+ + ++d ++ FUN_002208-T1 13 KKSDRVTVDHEKKSDGVRVHHEKKSDRVTVDHEKK 47 8899***************************9886 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0065 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktraav 144 ++++ +r+eyekk+ r + e + e ++ ++ + FUN_002208-T1 57 RQSDGVRVEYEKKSDGVRVHHETKSEGLRVHHEKERW 93 6778899999999998888888888777777666655 PP >> PCC_BT Propionyl-coenzyme A carboxylase BT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.7 5.5 0.003 5.4 36 115 .. 9 90 .. 2 92 .. 0.76 Alignments for each domain: == domain 1 score: 7.7 bits; conditional E-value: 0.003 PCC_BT 36 vvvkgedekvtveveedgdevevevdgesvevssdwklgdpliratvdgep..vtvqvekraggfrLrhrGtkfkvqVltpr 115 v+ k++ ++vtv+ e+++d v+v+++ +s +v+ d + + +r+ + ++ v v++ek++ g+r++h + ++V+ ++ FUN_002208-T1 9 VHHKKKSDRVTVDHEKKSDGVRVHHEKKSDRVTVDHEKKSDGVRVYHERQSdgVRVEYEKKSDGVRVHHETKSEGLRVHHEK 90 5556777889999999999999999998888888888888888888777664477777999999999998888888777765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1106 (0.0432961); expected 510.9 (0.02) Passed bias filter: 464 (0.018164); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1043.79 // Query: FUN_002209-T1 [L=266] Description: FUN_002209 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00011 21.2 1.3 0.095 11.5 0.3 2.9 2 Gp58 gp58-like protein ------ inclusion threshold ------ 0.01 16.7 33.3 3.3 8.7 2.1 6.2 6 DUF2554 Protein of unknown function (DUF2554) 0.25 12.9 0.5 49 5.6 0.0 3.6 3 Pheromone Fungal mating-type pheromone 2.7 7.9 12.1 15 5.6 0.2 4.0 5 DUF1444 Protein of unknown function (DUF1444) Domain annotation for each model (and alignments): >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.5 0.3 1.5e-05 0.095 152 254 .. 43 145 .. 25 165 .. 0.83 2 ! 6.8 0.1 0.00038 2.5 170 255 .. 168 253 .. 151 258 .. 0.70 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 1.5e-05 Gp58 152 ieGirreyqdadrqlsssyqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrvel 247 +G+r +++ + ++ +Gl ++ + G++ + + g+ ++++e + + + s+ + +e+k d+lr ++ + + Gmrv+ FUN_002209-T1 43 RDGVRVHHERKSNGVRVDHERKRDGLSVDHEKKSHGVRVDREKKSDGMRVHHEKERWGERDHYEKRSDWVRDDHEKKSDGLRVHHKKKSHGMRVDQ 138 56777777777777777888888999999999999999999999999999999999999999********************************** PP Gp58 248 eskisGl 254 e k G+ FUN_002209-T1 139 EEKSKGF 145 *998885 PP == domain 2 score: 6.8 bits; conditional E-value: 0.00038 Gp58 170 yqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveleskisGlq 255 +++ +G+ + + Gl+ + + g+ ++ + ++ k + s+G +e++ d++ ++ + + G+r + e k G++ FUN_002209-T1 168 HEKKSDGVGVHHEIKSGGLRVHHEKKRDGVRVYHERKSDGMRVKHEKKSEGVNVDHEKRSDGVTVHHEKKSDGVRLQHERKCDGVR 253 55555555555555555677777777777777777777778888888888888888888888888888888888888888887766 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 2.1 0.00051 3.3 39 65 .. 26 52 .. 5 63 .. 0.86 2 ? 4.8 1.5 0.0081 51 38 65 .. 69 96 .. 59 105 .. 0.84 3 ? 4.9 1.1 0.0077 49 41 65 .. 105 129 .. 97 139 .. 0.83 4 ? 4.9 0.2 0.0076 49 35 65 .. 162 192 .. 159 196 .. 0.86 5 ? 4.7 0.2 0.009 57 38 63 .. 198 223 .. 192 228 .. 0.83 6 ? 8.0 1.4 0.00086 5.5 38 65 .. 231 258 .. 220 265 .. 0.84 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00051 DUF2554 39 lrheadsdelravaeesaeGlrehfyw 65 + h+ sd lra e+ +G+r h+ FUN_002209-T1 26 VDHKKKSDRLRADHEKKRDGVRVHHER 52 569999******************974 PP == domain 2 score: 4.8 bits; conditional E-value: 0.0081 DUF2554 38 qlrheadsdelravaeesaeGlrehfyw 65 + he s +r e+ ++G+r h+ FUN_002209-T1 69 SVDHEKKSHGVRVDREKKSDGMRVHHEK 96 5679999*****************9964 PP == domain 3 score: 4.9 bits; conditional E-value: 0.0077 DUF2554 41 headsdelravaeesaeGlrehfyw 65 +e sd +r e+ ++Glr h++ FUN_002209-T1 105 YEKRSDWVRDDHEKKSDGLRVHHKK 129 6788999999999999****99974 PP == domain 4 score: 4.9 bits; conditional E-value: 0.0076 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfyw 65 ++ + he sd + e + Glr h+ FUN_002209-T1 162 AGVSVNHEKKSDGVGVHHEIKSGGLRVHHEK 192 566789**********************975 PP == domain 5 score: 4.7 bits; conditional E-value: 0.009 DUF2554 38 qlrheadsdelravaeesaeGlrehf 63 ++ he sd +r e+ +eG+ + FUN_002209-T1 198 RVYHERKSDGMRVKHEKKSEGVNVDH 223 678******************97655 PP == domain 6 score: 8.0 bits; conditional E-value: 0.00086 DUF2554 38 qlrheadsdelravaeesaeGlrehfyw 65 + he sd +r e +G+r h+ FUN_002209-T1 231 TVHHEKKSDGVRLQHERKCDGVRVHHEK 258 578**********************963 PP >> Pheromone Fungal mating-type pheromone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.1 0.054 3.5e+02 42 58 .. 51 67 .. 48 81 .. 0.77 2 ? -1.1 0.0 0.91 5.8e+03 44 59 .. 160 176 .. 156 178 .. 0.77 3 ? 5.6 0.0 0.0076 49 42 60 .. 213 232 .. 202 234 .. 0.84 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.054 Pheromone 42 ddevddvpvDaErrggg 58 + +++v vD+Er +g FUN_002209-T1 51 ERKSNGVRVDHERKRDG 67 66778888888887776 PP == domain 2 score: -1.1 bits; conditional E-value: 0.91 Pheromone 44 evddvpvDaErrggg.t 59 + +v v++E+ +g + FUN_002209-T1 160 KSAGVSVNHEKKSDGvG 176 567899****9999855 PP == domain 3 score: 5.6 bits; conditional E-value: 0.0076 Pheromone 42 ddevddvpvDaErrggg.ta 60 + + +v vD+E+r +g t+ FUN_002209-T1 213 EKKSEGVNVDHEKRSDGvTV 232 667889**********9665 PP >> DUF1444 Protein of unknown function (DUF1444) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.2 0.051 3.2e+02 21 44 .. 26 49 .. 6 61 .. 0.57 2 ? 1.9 0.8 0.029 1.9e+02 19 44 .. 46 71 .. 28 97 .. 0.56 3 ? 5.6 0.2 0.0023 15 15 59 .. 119 163 .. 107 183 .. 0.78 4 ? 5.4 0.3 0.0026 16 12 46 .. 190 224 .. 178 243 .. 0.77 5 ? -0.7 0.0 0.18 1.2e+03 16 44 .. 227 255 .. 221 259 .. 0.77 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.051 DUF1444 21 lkfdreedtlriedkktkkgvtik 44 + +++++d+lr ++k++ gv ++ FUN_002209-T1 26 VDHKKKSDRLRADHEKKRDGVRVH 49 444455555555555555554443 PP == domain 2 score: 1.9 bits; conditional E-value: 0.029 DUF1444 19 vtlkfdreedtlriedkktkkgvtik 44 v+++++r+++ +r+ +++++ g++++ FUN_002209-T1 46 VRVHHERKSNGVRVDHERKRDGLSVD 71 44444444444444444444444433 PP == domain 3 score: 5.6 bits; conditional E-value: 0.0023 DUF1444 15 keeevtlkfdreedtlriedkktkkgvtiklkeliakyeekkeka 59 k++ +++++++++ +r+ ++++ kg ti+ ++ + ++ekk + FUN_002209-T1 119 KSDGLRVHHKKKSHGMRVDQEEKSKGFTIRKSDGVRVHDEKKSAG 163 455677888899999999999999999998877777776666655 PP == domain 4 score: 5.4 bits; conditional E-value: 0.0026 DUF1444 12 eklkeeevtlkfdreedtlriedkktkkgvtiklk 46 ++ k++ v++ ++r++d +r++++k+ +gv+++ + FUN_002209-T1 190 HEKKRDGVRVYHERKSDGMRVKHEKKSEGVNVDHE 224 45567788899999999999999999999998755 PP == domain 5 score: -0.7 bits; conditional E-value: 0.18 DUF1444 16 eeevtlkfdreedtlriedkktkkgvtik 44 ++ vt+++++++d +r++++++ gv ++ FUN_002209-T1 227 SDGVTVHHEKKSDGVRLQHERKCDGVRVH 255 56678889999999999998888888765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (266 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1054 (0.0412605); expected 510.9 (0.02) Passed bias filter: 305 (0.0119397); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 2647.87 // Query: FUN_002210-T1 [L=138] Description: FUN_002210 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.014 15.8 2.1 19 5.8 0.1 3.7 3 DUF1869 Domain of unknown function (DUF1869) 0.014 14.3 0.2 0.017 14.0 0.2 1.1 1 Gp58 gp58-like protein 0.024 16.2 0.6 25 6.5 0.0 3.2 4 Pheromone Fungal mating-type pheromone 0.033 15.1 18.4 2.3 9.2 2.4 3.9 3 DUF2554 Protein of unknown function (DUF2554) 0.072 13.5 1.3 10 6.6 0.1 2.6 2 ComGE Competence system putative prepilin ComGE 0.31 11.5 13.0 31 5.1 0.0 5.5 6 Beta-APP Beta-amyloid peptide (beta-APP) 0.55 9.9 12.4 6.4 6.4 1.2 3.1 3 DUF632 Protein of unknown function (DUF632) 1.6 9.1 8.7 6 7.2 2.3 2.1 2 DA_C Diels-Alderase, C-terminal domain Domain annotation for each model (and alignments): >> DUF1869 Domain of unknown function (DUF1869) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.0059 19 11 24 .. 55 68 .. 45 83 .. 0.80 2 ? 5.3 0.1 0.0082 26 11 22 .. 88 99 .. 78 104 .. 0.84 3 ? 2.6 0.0 0.056 1.8e+02 7 23 .. 106 122 .. 100 129 .. 0.74 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.0059 DUF1869 11 NknNGVSVDkdfet 24 k+NGV VD++ + FUN_002210-T1 55 RKSNGVRVDHEKRS 68 599******99755 PP == domain 2 score: 5.3 bits; conditional E-value: 0.0082 DUF1869 11 NknNGVSVDkdf 22 k+NGV VD++ FUN_002210-T1 88 RKSNGVKVDHEK 99 59*******986 PP == domain 3 score: 2.6 bits; conditional E-value: 0.056 DUF1869 7 lTvTNknNGVSVDkdfe 23 + k+ GV VD++ + FUN_002210-T1 106 VHHEKKSHGVRVDHEKK 122 44456899****99865 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.2 5.3e-06 0.017 155 256 .. 27 128 .. 10 133 .. 0.91 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 5.3e-06 Gp58 155 irreyqdadrqlsssyqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrvelesk 250 +r ++++ + l + +++ +G++ + + G++ + + g++ +++++ ++ + + s+G +e++ d++ ++ + + G+rv+ e k FUN_002210-T1 27 VRVDHKKKSDSLRADHEKKRDGVRVHHERKSNGVRVDHEKRSDGVTVHHEKKSDGVRLQHERKSNGVKVDHEKRSDGVTVHHEKKSHGVRVDHEKK 122 677888888999999999*******9999999***********************************999************************** PP Gp58 251 isGlqs 256 Gl+ FUN_002210-T1 123 SDGLRN 128 999986 PP >> Pheromone Fungal mating-type pheromone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 1.1 3.6e+03 37 54 .. 38 55 .. 30 61 .. 0.59 2 ? 6.0 0.0 0.011 36 41 60 .. 53 73 .. 50 75 .. 0.85 3 ? 6.5 0.0 0.0077 25 41 60 .. 86 106 .. 83 108 .. 0.85 4 ? -0.8 0.0 1.6 5e+03 44 58 .. 111 125 .. 107 129 .. 0.76 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 1.1 Pheromone 37 ssslsddevddvpvDaEr 54 ++++ d+v v +Er FUN_002210-T1 38 LRADHEKKRDGVRVHHER 55 444555556666666666 PP == domain 2 score: 6.0 bits; conditional E-value: 0.011 Pheromone 41 sddevddvpvDaErrggg.ta 60 ++ +++v vD+E+r +g t+ FUN_002210-T1 53 HERKSNGVRVDHEKRSDGvTV 73 677899***********9665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0077 Pheromone 41 sddevddvpvDaErrggg.ta 60 ++ +++v vD+E+r +g t+ FUN_002210-T1 86 HERKSNGVKVDHEKRSDGvTV 106 678899***********9665 PP == domain 4 score: -0.8 bits; conditional E-value: 1.6 Pheromone 44 evddvpvDaErrggg 58 + +v vD+E+ +g FUN_002210-T1 111 KSHGVRVDHEKKSDG 125 5668889***98877 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 3.3 0.00078 2.5 39 64 .. 29 54 .. 2 61 .. 0.84 2 ? 4.5 1.0 0.021 67 39 60 .. 73 94 .. 56 108 .. 0.56 3 ? 9.2 2.4 0.00072 2.3 38 64 .. 105 131 .. 94 138 .] 0.85 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.00078 DUF2554 39 lrheadsdelravaeesaeGlrehfy 64 + h+ sd lra e+ +G+r h+ FUN_002210-T1 29 VDHKKKSDSLRADHEKKRDGVRVHHE 54 568999******************97 PP == domain 2 score: 4.5 bits; conditional E-value: 0.021 DUF2554 39 lrheadsdelravaeesaeGlr 60 + he sd +r e ++G++ FUN_002210-T1 73 VHHEKKSDGVRLQHERKSNGVK 94 3455555555555554444444 PP == domain 3 score: 9.2 bits; conditional E-value: 0.00072 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he s +r e+ ++Glr+h+ FUN_002210-T1 105 TVHHEKKSHGVRVDHEKKSDGLRNHHE 131 578**********************96 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.1 0.0078 25 55 77 .. 56 78 .. 48 80 .. 0.88 2 ? 6.6 0.1 0.0032 10 53 77 .. 87 111 .. 83 117 .. 0.88 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.0078 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv v ++ +++++v +++k FUN_002210-T1 56 KSNGVRVDHEKRSDGVTVHHEKK 78 56*****************9987 PP == domain 2 score: 6.6 bits; conditional E-value: 0.0032 ComGE 53 eLslNGvevtvkenqeelivlesgk 77 e + NGv+v ++ +++++v +++k FUN_002210-T1 87 ERKSNGVKVDHEKRSDGVTVHHEKK 111 5677*****************9987 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.0 0.012 38 2 14 .. 11 23 .. 10 25 .. 0.92 2 ? 4.5 0.0 0.015 49 1 14 [. 54 67 .. 54 68 .. 0.94 3 ? 1.7 0.4 0.12 3.7e+02 1 14 [. 65 78 .. 65 79 .. 0.84 4 ? 5.1 0.0 0.0098 31 1 14 [. 87 100 .. 87 104 .. 0.94 5 ? 1.8 0.4 0.1 3.2e+02 1 14 [. 98 111 .. 98 113 .. 0.84 6 ? 0.4 0.1 0.29 9.2e+02 1 14 [. 109 122 .. 109 124 .. 0.84 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.012 Beta-APP 2 RQSAsyEVYHEKl 14 R+S + V HEK+ FUN_002210-T1 11 RKSDGMRVHHEKR 23 8999********8 PP == domain 2 score: 4.5 bits; conditional E-value: 0.015 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + V HEK+ FUN_002210-T1 54 ERKSNGVRVDHEKR 67 89***********8 PP == domain 3 score: 1.7 bits; conditional E-value: 0.12 Beta-APP 1 eRQSAsyEVYHEKl 14 e+ S + V HEK+ FUN_002210-T1 65 EKRSDGVTVHHEKK 78 56788999*****6 PP == domain 4 score: 5.1 bits; conditional E-value: 0.0098 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + V HEK+ FUN_002210-T1 87 ERKSNGVKVDHEKR 100 89***********8 PP == domain 5 score: 1.8 bits; conditional E-value: 0.1 Beta-APP 1 eRQSAsyEVYHEKl 14 e+ S + V HEK+ FUN_002210-T1 98 EKRSDGVTVHHEKK 111 56788999*****6 PP == domain 6 score: 0.4 bits; conditional E-value: 0.29 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002210-T1 109 EKKSHGVRVDHEKK 122 56788999****96 PP >> DUF632 Protein of unknown function (DUF632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 1.2 0.002 6.4 108 142 .. 22 56 .. 16 61 .. 0.90 2 ? 6.0 0.4 0.0028 8.8 108 142 .. 66 100 .. 63 108 .. 0.88 3 ? 4.5 0.3 0.0077 24 108 131 .. 110 133 .. 106 137 .. 0.89 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.002 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K ++ +r++++kk+ Lr ek+ + ++ r+ FUN_002210-T1 22 KRSDWVRVDHKKKSDSLRADHEKKRDGVRVHHERK 56 788999*****************999999988886 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0028 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K ++ + + +ekk+ r + e++ + k+d + FUN_002210-T1 66 KRSDGVTVHHEKKSDGVRLQHERKSNGVKVDHEKR 100 77888999999999999999999999999998775 PP == domain 3 score: 4.5 bits; conditional E-value: 0.0077 DUF632 108 KaeeklrieyekkckqLrkleekg 131 K++ +r+++ekk+ Lr++ ek+ FUN_002210-T1 110 KKSHGVRVDHEKKSDGLRNHHEKE 133 778889*************99986 PP >> DA_C Diels-Alderase, C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.7 0.0043 14 61 107 .. 22 68 .. 5 75 .. 0.68 2 ? 7.2 2.3 0.0019 6 59 109 .. 75 125 .. 68 136 .. 0.81 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0043 DA_C 61 ktedsvvlekavdgekvakekvkegegvtGafrdkntGyvlefvspe 107 k++d v ++++ +++++ +++k+ +gv+ + + k+ G +++ +++ FUN_002210-T1 22 KRSDWVRVDHKKKSDSLRADHEKKRDGVRVHHERKSNGVRVDHEKRS 68 23333445555566677788888888999999999999888876655 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0019 DA_C 59 vsktedsvvlekavdgekvakekvkegegvtGafrdkntGyvlefvspeeg 109 ++k++d v l+++++++ v+++++k+++gvt + + k+ G +++ ++++g FUN_002210-T1 75 HEKKSDGVRLQHERKSNGVKVDHEKRSDGVTVHHEKKSHGVRVDHEKKSDG 125 45677888899999999999************************9886554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (138 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 745 (0.0291642); expected 510.9 (0.02) Passed bias filter: 263 (0.0102956); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.23u 0.40s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1412.98 // Query: FUN_002211-T1 [L=321] Description: FUN_002211 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-05 25.1 0.8 0.00054 20.2 0.0 3.1 2 HIRAN HIRAN domain ------ inclusion threshold ------ 0.051 14.5 13.6 1.4 9.8 1.4 4.5 4 DUF2554 Protein of unknown function (DUF2554) 1.1 9.8 5.4 21 5.6 0.1 3.8 4 PH_FT_C PH domain found in tandem in fungal proteins 3 7.9 15.0 14 5.8 1.1 4.3 4 DNA_ligase_A_M ATP dependent DNA ligase domain Domain annotation for each model (and alignments): >> HIRAN HIRAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.0 8.4e-08 0.00054 10 60 .. 15 64 .. 11 68 .. 0.84 2 ? 1.6 0.8 0.056 3.6e+02 32 44 .. 228 267 .. 142 315 .. 0.70 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 8.4e-08 HIRAN 10 gtrYysgtrklkigeivklvrepqnpydsnavrvytedgeeiGylprevak 60 g++ y+ + + + gei++l++ep+n+ d+nav+v+ +++++i ++p ++a+ FUN_002211-T1 15 GFHVYKDWWTTTCGEILHLQPEPENAEDKNAVAVL-KESRVISHIPYHLAN 64 55556666677789*********************.888899999988775 PP == domain 2 score: 1.6 bits; conditional E-value: 0.056 HIRAN 32 p...........................qnpydsnavrvy 44 + q + sn vrv+ FUN_002211-T1 228 SdgvrvnhekksdgvkvdhekksdgvrlQHERKSNGVRVT 267 3333332222223333333334455555555555555555 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.1 0.081 5.2e+02 41 64 .. 158 181 .. 150 192 .. 0.58 2 ? 3.7 0.9 0.018 1.1e+02 40 66 .. 190 216 .. 181 237 .. 0.60 3 ? 4.8 0.6 0.0085 54 39 60 .. 233 254 .. 215 281 .. 0.61 4 ? 9.8 1.4 0.00022 1.4 37 64 .. 285 312 .. 275 320 .. 0.85 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.081 DUF2554 41 headsdelravaeesaeGlrehfy 64 ++ sd +r e+ ++G+r + FUN_002211-T1 158 KKKKSDGVRVHDEKKSNGVRVVHE 181 555566666666666666665443 PP == domain 2 score: 3.7 bits; conditional E-value: 0.018 DUF2554 40 rheadsdelravaeesaeGlrehfywq 66 h+ sd + e+ ++G+r h+ + FUN_002211-T1 190 NHDKKSDGVGVDHEKKSNGVRIHHEKK 216 566666666666666666666665433 PP == domain 3 score: 4.8 bits; conditional E-value: 0.0085 DUF2554 39 lrheadsdelravaeesaeGlr 60 + he sd ++ e+ ++G+r FUN_002211-T1 233 VNHEKKSDGVKVDHEKKSDGVR 254 3444444444444444444444 PP == domain 4 score: 9.8 bits; conditional E-value: 0.00022 DUF2554 37 hqlrheadsdelravaeesaeGlrehfy 64 ++ he sd +r e +eG+r h++ FUN_002211-T1 285 VRVHHEKKSDGVRLQHERKSEGVRVHHK 312 5678**********************96 PP >> PH_FT_C PH domain found in tandem in fungal proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.11 6.8e+02 7 31 .. 166 190 .. 160 197 .. 0.81 2 ? 5.6 0.1 0.0033 21 6 32 .. 209 235 .. 204 244 .. 0.84 3 ? -0.7 0.0 0.3 1.9e+03 11 29 .. 247 265 .. 237 276 .. 0.58 4 ? 3.0 0.2 0.021 1.4e+02 8 32 .. 276 300 .. 269 310 .. 0.81 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.11 PH_FT_C 7 eIlddgyehaLrvyrdrksgavRLe 31 +++d++ rv +++ks +vR++ FUN_002211-T1 166 RVHDEKKSNGVRVVHEKKSAGVRVN 190 6788888888999999999999975 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0033 PH_FT_C 6 geIlddgyehaLrvyrdrksgavRLea 32 +I++++ + rvy++rks++vR++ FUN_002211-T1 209 VRIHHEKKRDGVRVYHERKSDGVRVNH 235 68999999999*************875 PP == domain 3 score: -0.7 bits; conditional E-value: 0.3 PH_FT_C 11 dgyehaLrvyrdrksgavR 29 ++ r+ ++rks++vR FUN_002211-T1 247 EKKSDGVRLQHERKSNGVR 265 3333344455555555555 PP == domain 4 score: 3.0 bits; conditional E-value: 0.021 PH_FT_C 8 IlddgyehaLrvyrdrksgavRLea 32 + +++ + rv +++ks++vRL+ FUN_002211-T1 276 VDHEKRRDGVRVHHEKKSDGVRLQH 300 66677777899************96 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 0.63 4e+03 27 43 .. 161 177 .. 159 180 .. 0.73 2 ? 5.2 1.3 0.0032 21 18 43 .. 218 243 .. 193 246 .. 0.72 3 ? 5.8 1.1 0.0022 14 24 50 .. 246 272 .. 237 286 .. 0.83 4 ? 3.8 0.3 0.009 58 22 44 .. 287 309 .. 278 317 .. 0.79 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 0.63 DNA_ligase_A_M 27 KyDGeRaqvhkegdevk 43 K DG+R+ +k+++ v+ FUN_002211-T1 161 KSDGVRVHDEKKSNGVR 177 88999988777777665 PP == domain 2 score: 5.2 bits; conditional E-value: 0.0032 DNA_ligase_A_M 18 egkafivEiKyDGeRaqvhkegdevk 43 +g ++ E K DG+R+ +k++d vk FUN_002211-T1 218 DGVRVYHERKSDGVRVNHEKKSDGVK 243 34456677777777777777777665 PP == domain 3 score: 5.8 bits; conditional E-value: 0.0022 DNA_ligase_A_M 24 vEiKyDGeRaqvhkegdevklfSRnle 50 E K DG+R+q +++++ v+++ R+++ FUN_002211-T1 246 HEKKSDGVRLQHERKSNGVRVTMRKSD 272 699****************99999876 PP == domain 4 score: 3.8 bits; conditional E-value: 0.009 DNA_ligase_A_M 22 fivEiKyDGeRaqvhkegdevkl 44 ++ E K DG+R+q +++++ v++ FUN_002211-T1 287 VHHEKKSDGVRLQHERKSEGVRV 309 56799999999999988887765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (321 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1125 (0.0440399); expected 510.9 (0.02) Passed bias filter: 451 (0.0176551); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.36u 0.36s 00:00:00.72 Elapsed: 00:00:00.41 # Mc/sec: 3157.16 // Query: FUN_002215-T1 [L=210] Description: FUN_002215 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.099 13.1 0.2 0.29 11.6 0.2 1.8 1 Erythro-docking Erythronolide synthase, docking Domain annotation for each model (and alignments): >> Erythro-docking Erythronolide synthase, docking # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.2 1.1e-05 0.29 8 37 .. 41 70 .. 31 76 .. 0.85 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.1e-05 Erythro-docking 8 vGdRLDeLekaLeaLsdedGhdDvGaRLea 37 dRL Le LeaL +++G + v a L + FUN_002215-T1 41 ASDRLKLLEDKLEALEEKQGGNTVSAALSS 70 569*********************999977 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (210 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 987 (0.0386377); expected 510.9 (0.02) Passed bias filter: 739 (0.0289293); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.41s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2090.87 // Query: FUN_002216-T1 [L=334] Description: FUN_002216 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-38 129.5 9.3 2.1e-05 25.0 0.0 8.0 8 Ank Ankyrin repeat 1.5e-32 112.5 3.2 3.7e-11 43.9 0.2 4.6 4 Ank_2 Ankyrin repeats (3 copies) 7.9e-27 93.2 3.6 0.0001 23.0 0.0 7.1 7 Ank_4 Ankyrin repeats (many copies) 2.1e-22 79.4 7.3 0.0001 23.1 0.1 6.1 6 Ank_5 Ankyrin repeats (many copies) 1.2e-18 65.5 3.0 0.012 16.5 0.0 7.8 8 Ank_3 Ankyrin repeat 2.5e-05 24.5 0.0 0.14 12.3 0.0 3.2 3 Ank_KRIT1 KRIT1 ankyrin-repeats domain Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.3 0.0 0.00012 0.51 1 30 [. 49 79 .. 49 82 .. 0.90 2 ! 20.1 0.0 1.8e-07 0.00077 4 30 .. 98 124 .. 98 126 .. 0.88 3 ! 12.7 0.0 4.3e-05 0.18 15 33 .] 156 174 .. 130 174 .. 0.87 4 ! 20.6 0.3 1.3e-07 0.00057 1 32 [. 178 210 .. 178 211 .. 0.91 5 ! 15.1 0.0 7.2e-06 0.031 3 32 .. 214 243 .. 212 244 .. 0.94 6 ! 25.0 0.0 5e-09 2.1e-05 2 32 .. 246 276 .. 245 277 .. 0.91 7 ! 22.1 0.1 4.2e-08 0.00018 3 33 .] 280 316 .. 278 316 .. 0.87 8 ? -0.2 0.0 0.54 2.3e+03 2 10 .. 318 326 .. 317 331 .. 0.74 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00012 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvna 30 +G ++L +A+ ++++v+ LLk +Ad+n FUN_002216-T1 49 YGLSALCMAVkAFQSPSLVEKLLKMNADPNF 79 599*******98899********779***95 PP == domain 2 score: 20.1 bits; conditional E-value: 1.8e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvna 30 +PLH+Aa h+ + k LL+ GAd+n FUN_002216-T1 98 SPLHVAAWLRHPGITKVLLDGGADPNT 124 6******999999******547***95 PP == domain 3 score: 12.7 bits; conditional E-value: 4.3e-05 Ank 15 levvklLLkhGAdvnardk 33 l+v+klL+++GAdv a+d+ FUN_002216-T1 156 LDVMKLLIYNGADVTAVDN 174 67******88******997 PP == domain 4 score: 20.6 bits; conditional E-value: 1.3e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA.dvnard 32 dG + LH+A + gh+ +v++LL+ A dvn+r+ FUN_002216-T1 178 DGTSLLHMATQGGHVLIVNYLLSLRAlDVNCRN 210 7999******************668879**998 PP == domain 5 score: 15.1 bits; conditional E-value: 7.2e-06 Ank 3 nTPLHlAaraghlevvklL.LkhGAdvnard 32 TPL++A r+++ e+++ L L hGA +n rd FUN_002216-T1 214 ETPLMIALREDRQELLEDLpL-HGAHPNSRD 243 7********************.8******98 PP == domain 6 score: 25.0 bits; conditional E-value: 5e-09 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH+A+ + +++ v++L+++ Advn +d FUN_002216-T1 246 GCTALHIAVGRTCVKSVEILIQNSADVNMKD 276 9********778899******878*****99 PP == domain 7 score: 22.1 bits; conditional E-value: 4.2e-08 Ank 3 nTPLHlAaragh......levvklLLkhGAdvnardk 33 +T+LH+A+r ++ ++v+k LL+++Advn+ d+ FUN_002216-T1 280 RTALHVASRLNNsssksnVKVMKSLLSNNADVNVADN 316 7*******6666677778********879*****997 PP == domain 8 score: -0.2 bits; conditional E-value: 0.54 Ank 2 GnTPLHlAa 10 G+ PLHl + FUN_002216-T1 318 GRRPLHLTV 326 888***977 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.0 7.6e-09 3.2e-05 18 88 .. 39 124 .. 29 126 .. 0.77 2 ! 43.9 0.2 8.8e-15 3.7e-11 9 90 .] 155 243 .. 151 243 .. 0.89 3 ! 32.6 0.2 3e-11 1.3e-07 12 72 .. 228 291 .. 225 295 .. 0.88 4 ! 17.4 0.1 1.7e-06 0.0071 30 68 .. 280 326 .. 280 331 .. 0.76 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 7.6e-09 Ank_2 18 egadanlqdkngetaLhlAak.nghleivklLlehgad....vndnn.............grtaLhyAaesghleivklLlekgadina 88 e++++n++++ g +aL +A+k ++ +v+ Ll+ +ad + ++Lh+Aa+ +h i k+Ll+ gad+n+ FUN_002216-T1 39 EKQNPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADpnfeS---YigkflgtrktekpSGSPLHVAAWLRHPGITKVLLDGGADPNT 124 678999999************5567899*99999766633440...24444455555555558******************99****97 PP == domain 2 score: 43.9 bits; conditional E-value: 8.8e-15 Ank_2 9 nlelvklLl.egadanlqdk...ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+++klL+ +gad+ +d+ +g++ Lh+A + gh+ iv +Ll+ dvn + + +t+L++A +++++e ++ L +ga++n++d FUN_002216-T1 155 ALDVMKLLIyNGADVTAVDNtktDGTSLLHMATQGGHVLIVNYLLSLRaLDVNcrNIHEETPLMIALREDRQELLEDLPLHGAHPNSRD 243 46899*********997777799**********************9654667776888********************989***99987 PP == domain 3 score: 32.6 bits; conditional E-value: 3e-11 Ank_2 12 lvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesgh 72 l++ L +ga +n++d g taLh+A+ + ++ v++L++++advn d++ rtaLh+A++ ++ FUN_002216-T1 228 LLEDLPlHGAHPNSRDMAGCTALHIAVGRTCVKSVEILIQNSADVNmkDSSCRTALHVASRLNN 291 56666448999999889***********************99999999999********99876 PP == domain 4 score: 17.4 bits; conditional E-value: 1.7e-06 Ank_2 30 etaLhlAakng......hleivklLlehgadvn..dnngrtaLhyAa 68 +taLh+A + + +++++k Ll+++advn dn+gr +Lh+ + FUN_002216-T1 280 RTALHVASRLNnsssksNVKVMKSLLSNNADVNvaDNQGRRPLHLTV 326 599999999552333335566899999999999999*******9866 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.33 1.4e+03 22 49 .. 42 70 .. 37 78 .. 0.66 2 ! 5.9 0.0 0.0058 25 1 40 [. 100 139 .. 98 142 .. 0.83 3 ! 23.0 0.0 2.5e-08 0.0001 7 50 .] 153 199 .. 150 199 .. 0.86 4 ! 11.9 0.0 7.3e-05 0.31 8 42 .. 190 225 .. 190 232 .. 0.86 5 ! 13.3 0.1 2.8e-05 0.12 4 39 .. 220 255 .. 217 257 .. 0.86 6 ! 22.6 0.0 3.1e-08 0.00013 9 39 .. 258 288 .. 255 294 .. 0.90 7 ! 18.1 0.0 8.2e-07 0.0035 7 35 .. 295 323 .. 292 326 .. 0.94 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.33 Ank_4 22 dinatdgngetaLhfAa.sngnlevlklL 49 ++n ++ +g +aL +A+ ++ +++ ++ L FUN_002216-T1 42 NPNFVNSYGLSALCMAVkAFQSPSLVEKL 70 55666778888888887555555555555 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0058 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasn 40 lh+Aa h + k Ll+ gad+n++ n t+L ++ n FUN_002216-T1 100 LHVAAWLRHPGITKVLLDGGADPNTVaF-NSLTPLLLVLTN 139 68888889999999***99*******65.589999887765 PP == domain 3 score: 23.0 bits; conditional E-value: 2.5e-08 Ank_4 7 sghlellklLlengadinat.d..gngetaLhfAasngnlevlklLl 50 + l++ klL+ ngad+ a+ + +g + Lh+A ++g++ ++ +Ll FUN_002216-T1 153 QAALDVMKLLIYNGADVTAVdNtkTDGTSLLHMATQGGHVLIVNYLL 199 5669************9988434466999**************9997 PP == domain 4 score: 11.9 bits; conditional E-value: 7.3e-05 Ank_4 8 ghlellklLlen.gadinatdgngetaLhfAasngn 42 gh+ ++ +Ll+ +d+n+++ et+L +A++ + FUN_002216-T1 190 GHVLIVNYLLSLrALDVNCRNIHEETPLMIALREDR 225 79999*****9956*****************98665 PP == domain 5 score: 13.3 bits; conditional E-value: 2.8e-05 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAas 39 A + ++ell+ L +ga++n +d g taLh+A+ FUN_002216-T1 220 ALREDRQELLEDLPLHGAHPNSRDMAGCTALHIAVG 255 666788999999999*******************96 PP == domain 6 score: 22.6 bits; conditional E-value: 3.1e-08 Ank_4 9 hlellklLlengadinatdgngetaLhfAas 39 +++ ++ L++n ad+n+ d +++taLh A++ FUN_002216-T1 258 CVKSVEILIQNSADVNMKDSSCRTALHVASR 288 7899*************************86 PP == domain 7 score: 18.1 bits; conditional E-value: 8.2e-07 Ank_4 7 sghlellklLlengadinatdgngetaLh 35 ++++++ k+Ll+n ad+n d++g+ +Lh FUN_002216-T1 295 KSNVKVMKSLLSNNADVNVADNQGRRPLH 323 789************************** PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.5 0.0 0.00021 0.89 8 43 .. 42 78 .. 37 79 .. 0.88 2 ! 20.6 0.0 1.5e-07 0.00063 18 53 .. 98 133 .. 92 135 .. 0.95 3 ? 1.8 0.0 0.11 4.7e+02 26 47 .. 153 174 .. 151 177 .. 0.86 4 ! 15.4 0.2 6.1e-06 0.026 13 56 .] 176 220 .. 171 220 .. 0.89 5 ! 23.1 0.1 2.4e-08 0.0001 7 56 .] 239 286 .. 234 286 .. 0.85 6 ! 7.1 0.0 0.0025 11 20 55 .. 289 324 .. 289 325 .. 0.82 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00021 Ank_5 8 dlnrldgegytpLhvAak.ygaleivrlLlangvdln 43 ++n + +g +L++A+k ++ +v++Ll+ ++d+n FUN_002216-T1 42 NPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADPN 78 677779999*********************8888876 PP == domain 2 score: 20.6 bits; conditional E-value: 1.5e-07 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 pLhvAa+ +++ i ++Ll+ g+d+n+ ++ ltpl FUN_002216-T1 98 SPLHVAAWLRHPGITKVLLDGGADPNTVAFNSLTPL 133 79********************************98 PP == domain 3 score: 1.8 bits; conditional E-value: 0.11 Ank_5 26 ygaleivrlLlangvdlnlkde 47 + al++++lL+ ng+d+++ d+ FUN_002216-T1 153 QAALDVMKLLIYNGADVTAVDN 174 6799************999986 PP == domain 4 score: 15.4 bits; conditional E-value: 6.1e-06 Ank_5 13 dgegytpLhvAakygaleivrlLl.angvdlnlkdeegltpldlA 56 ++g+ Lh+A +g+ iv++Ll + d+n+++ + +tpl +A FUN_002216-T1 176 KTDGTSLLHMATQGGHVLIVNYLLsLRALDVNCRNIHEETPLMIA 220 4567799**********************************9777 PP == domain 5 score: 23.1 bits; conditional E-value: 2.4e-08 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + + g+ t+Lh+A+ + + v++L+ n +d+n+kd+++ t+l++A FUN_002216-T1 239 PNSRDMAGC--TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVA 286 444444445..************************************998 PP == domain 6 score: 7.1 bits; conditional E-value: 0.0025 Ank_5 20 LhvAakygaleivrlLlangvdlnlkdeegltpldl 55 L++ +++ + +++ Ll n++d+n+ d++g pl+l FUN_002216-T1 289 LNNSSSKSNVKVMKSLLSNNADVNVADNQGRRPLHL 324 566778888889999999999999999999877765 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.046 1.9e+02 8 30 .. 56 78 .. 49 79 .. 0.72 2 ! 10.9 0.0 0.00019 0.83 4 30 .. 98 123 .. 96 124 .. 0.95 3 ? -0.2 0.0 0.82 3.5e+03 13 29 .. 154 169 .. 151 171 .. 0.80 4 ! 10.0 0.1 0.0004 1.7 4 30 .. 181 207 .. 178 208 .. 0.87 5 ? 4.2 0.0 0.03 1.3e+02 3 21 .. 214 232 .. 212 241 .. 0.75 6 ! 16.5 0.0 2.9e-06 0.012 2 31 .] 246 274 .. 245 274 .. 0.96 7 ! 11.8 0.0 9.8e-05 0.42 3 31 .] 280 313 .. 280 313 .. 0.93 8 ? -2.3 0.0 4.1 1.8e+04 2 8 .. 318 324 .. 317 330 .. 0.75 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.046 Ank_3 8 lAarngrle.ivklLleklgadin 30 +A++ + + +v+ Ll+ ++ad+n FUN_002216-T1 56 MAVKAFQSPsLVEKLLK-MNADPN 78 55555555559******.****99 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00019 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa ++ i k+Ll+ gad+n FUN_002216-T1 98 SPLHVAAWLRHPGITKVLLD-GGADPN 123 8*******************.*****9 PP == domain 3 score: -0.2 bits; conditional E-value: 0.82 Ank_3 13 grleivklLleklgadi 29 + l+++klL+ +gad+ FUN_002216-T1 154 AALDVMKLLIY-NGADV 169 56799999999.99998 PP == domain 4 score: 10.0 bits; conditional E-value: 0.0004 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 ++Lh+A g++ iv +Ll + d+n FUN_002216-T1 181 SLLHMATQGGHVLIVNYLLSLRALDVN 207 89*****************98777777 PP == domain 5 score: 4.2 bits; conditional E-value: 0.03 Ank_3 3 ntpLhlAarngrleivklL 21 +tpL++A r +r e+++ L FUN_002216-T1 214 ETPLMIALREDRQELLEDL 232 8********9997777665 PP == domain 6 score: 16.5 bits; conditional E-value: 2.9e-06 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+t+Lh+A+ +++ v+ L++ + ad+n+ FUN_002216-T1 246 GCTALHIAVGRTCVKSVEILIQ-NSADVNM 274 89************99******.*****95 PP == domain 7 score: 11.8 bits; conditional E-value: 9.8e-05 Ank_3 3 ntpLhlAarngrl......eivklLleklgadina 31 +t+Lh+A r ++ +++k Ll ++ad+n+ FUN_002216-T1 280 RTALHVASRLNNSssksnvKVMKSLLS-NNADVNV 313 79***********99998889******.*****95 PP == domain 8 score: -2.3 bits; conditional E-value: 4.1 Ank_3 2 gntpLhl 8 g+ pLhl FUN_002216-T1 318 GRRPLHL 324 899***6 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.01 44 40 78 .. 89 127 .. 65 138 .. 0.71 2 ! 12.3 0.0 3.4e-05 0.14 42 99 .. 175 227 .. 164 254 .. 0.72 3 ! 4.5 0.0 0.0087 37 87 142 .. 248 303 .. 233 310 .. 0.82 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.01 Ank_KRIT1 40 vrekvddpes.lvaAakgGheevlqlLlalGkadpdPepv 78 r++ + + s l+ Aa+ h ++++Ll+ G+adp+ + FUN_002216-T1 89 TRKTEKPSGSpLHVAAWLRHPGITKVLLD-GGADPNTVAF 127 555444444459****************8.6688885444 PP == domain 2 score: 12.3 bits; conditional E-value: 3.4e-05 Ank_KRIT1 42 ekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlk 99 +k+d + l++A++gGh ++++Ll l d + + +++ +tPl+ a ++ + FUN_002216-T1 175 TKTDGTSLLHMATQGGHVLIVNYLLSLRALDVNCRNIHE-----ETPLMIALREDRQE 227 3444455589999*************9999999666554.....57777776555555 PP == domain 3 score: 4.5 bits; conditional E-value: 0.0087 Ank_KRIT1 87 tPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgenweeeeklLke 142 t l a+Gr +k +++l++++ ++ +t l +a + ++++ + + k++k+ FUN_002216-T1 248 TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVASRLNNSSSKSNVKVMKS 303 667789***********9976655455559999*******9999999999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (334 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 834 (0.0326483); expected 510.9 (0.02) Passed bias filter: 679 (0.0265805); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3314.81 // Query: FUN_002217-T1 [L=760] Description: FUN_002217 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-17 63.8 0.8 2e-16 60.6 0.4 2.5 2 Histone Core histone H2A/H2B/H3/H4 domain 6.8e-11 42.6 0.0 0.0002 22.1 0.0 2.6 2 Ank_4 Ankyrin repeats (many copies) 3.5e-07 30.7 0.1 0.18 12.7 0.0 3.7 3 Ank Ankyrin repeat 4.1e-07 30.2 0.0 8.3e-07 29.2 0.0 1.5 1 Histone_ABTB Histone domain in ABTB family protein 1.4e-06 29.0 0.0 4.4e-06 27.4 0.0 1.9 1 Mab-21 Mab-21 protein nucleotidyltransferase domain 1.8e-06 28.9 0.0 5.2e-06 27.4 0.0 1.8 1 Ank_2 Ankyrin repeats (3 copies) 2.9e-05 24.8 0.1 0.00077 20.3 0.1 2.6 1 Ank_5 Ankyrin repeats (many copies) ------ inclusion threshold ------ 0.052 14.3 0.0 0.14 12.9 0.0 1.8 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.45 1.4e+03 23 34 .. 8 19 .. 2 29 .. 0.78 2 ! 60.6 0.4 6.2e-20 2e-16 7 88 .] 658 735 .. 652 735 .. 0.94 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.45 Histone 23 lpfaRvvrevvk 34 f++v+re+v+ FUN_002217-T1 8 VEFQKVIRELVE 19 67********98 PP == domain 2 score: 60.6 bits; conditional E-value: 6.2e-20 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ +++++++++ ++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_002217-T1 658 AETAKRRRGKRKESYAIYKYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 735 57778899999*****************....************************************************97 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.3e-06 0.004 11 36 .. 12 37 .. 11 47 .. 0.91 2 ! 22.1 0.0 6.2e-08 0.0002 13 49 .. 55 91 .. 44 92 .. 0.93 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.3e-06 Ank_4 11 ellklLlengadinatdgngetaLhf 36 ++++ L+e g+din++d +g t+Lh+ FUN_002217-T1 12 KVIRELVEAGVDINCQDIEGSTCLHH 37 689**********************7 PP == domain 2 score: 22.1 bits; conditional E-value: 6.2e-08 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklL 49 + Ll+ gad na+d +g+t+ h+Aa +++ + l++L FUN_002217-T1 55 TRVLLDAGADRNARDIDGNTPAHIAAEGEDADQLRML 91 699*****************************99998 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.017 54 16 32 .. 12 28 .. 8 29 .. 0.89 2 ! 12.7 0.0 5.6e-05 0.18 2 32 .. 31 69 .. 30 70 .. 0.89 3 ! 8.6 0.0 0.0011 3.6 1 21 [. 71 91 .. 71 101 .. 0.86 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.017 Ank 16 evvklLLkhGAdvnard 32 +v++ L+++G+d+n++d FUN_002217-T1 12 KVIRELVEAGVDINCQD 28 699****99******98 PP == domain 2 score: 12.7 bits; conditional E-value: 5.6e-05 Ank 2 GnTPLHlAa.ragh.......levvklLLkhGAdvnard 32 G T+LH + r+g+ ++ + LL++GAd nard FUN_002217-T1 31 GSTCLHHTVgRKGRtsshlkfPDFTRVLLDAGADRNARD 69 99*****99977777778999********88*******9 PP == domain 3 score: 8.6 bits; conditional E-value: 0.0011 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP H+Aa+ + + +++L FUN_002217-T1 71 DGNTPAHIAAEGEDADQLRML 91 8*********87778877777 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.0 2.6e-10 8.3e-07 23 91 .. 689 759 .. 676 760 .] 0.86 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 2.6e-10 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_002217-T1 689 ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 759 67888888899999999***********99998763378***************************99865 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 1.4e-09 4.4e-06 3 193 .. 347 529 .. 345 533 .. 0.69 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 1.4e-09 Mab-21 3 enlkvlsPdeFdlvlkLklpeneeiivkedpggpgyvelkltrsg..esndnsrkellsqwleeaegylsaaKvlsrfqslvekalkklekeievn 96 e++k +PdeFd++ +L+ + +++ y+ l +++ s d++ ke ++++l + ++ ls++K++ f l +a l+++ + + FUN_002217-T1 347 EETKLWKPDEFDFMMELTQ--------LKGHSRLEYAGLSRSSNTtvISLDDEMKEMWREFL-K-DDCLSPEKLRDYFVLLTWRAGFSLQQQNY-K 431 789999***********92........2333335555555555223556667999*******.6.89************999999888644433.3 PP Mab-21 97 detlklsykrk.......gpavt.....vaietseeq..............ysVdlvpaielkasWpksasnwprclkrwpsqkvlekiksegfhl 166 + +ls ++ p v+ v ++Vdl++++++++ Wp + ++ p + ++ + g+h FUN_002217-T1 432 NLSFNLS--QQsggtgssHPLVRmssvgV-------LlhvqwhgydytsldIDVDLTLSVPFSD-WPVLLP---SDRSPQPAPAIF--DTTVGYHA 512 3333333..33668876633333333222.......133333346688899*************.**9877...345555555555..55889988 PP Mab-21 167 vakssykdqdekeedsWrlSFseaEka 193 + + y WrlSFs aE + FUN_002217-T1 513 ITDGAY----------WRLSFSLAELN 529 888666..........********976 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 1.6e-09 5.2e-06 11 80 .. 12 92 .. 7 106 .. 0.82 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 1.6e-09 Ank_2 11 elvklLl.egadanlqdkngetaLhlAakng.....hlei...vklLlehgadvn..dnngrtaLhyAaesghleivklLl 80 +++++L+ g+d+n+qd +g t Lh+ + + hl++ ++Ll+ gad n d +g+t+ h+Aae + +++L+ FUN_002217-T1 12 KVIRELVeAGVDINCQDIEGSTCLHHTVGRKgrtssHLKFpdfTRVLLDAGADRNarDIDGNTPAHIAAEGEDADQLRMLA 92 48999**9*****************9998543554455435559*****999988999***********988888888887 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.1 2.4e-07 0.00077 1 56 [] 17 79 .. 17 79 .. 0.89 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 2.4e-07 Ank_5 1 LlengpadlnrldgegytpLhvAak.yga.......leivrlLlangvdlnlkdeegltpldlA 56 L+e+g +d+n++d eg t+Lh+ + +g+ +++ r+Ll+ g+d n++d +g+tp ++A FUN_002217-T1 17 LVEAG-VDINCQDIEGSTCLHHTVGrKGRtsshlkfPDFTRVLLDAGADRNARDIDGNTPAHIA 79 89999.88888888999********99995555555689***********************98 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 4.5e-05 0.14 10 65 .] 678 733 .. 677 733 .. 0.95 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 4.5e-05 CBFD_NFYB_HMF 10 rImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_002217-T1 678 KVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 733 899***88888.*****************************************9986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (760 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 732 (0.0286553); expected 510.9 (0.02) Passed bias filter: 641 (0.025093); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 7239.48 // Query: FUN_002218-T1 [L=127] Description: FUN_002218 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.051 12.9 0.1 0.056 12.7 0.1 1.1 1 ECM29_N Proteasome component ECM29, N-terminal Domain annotation for each model (and alignments): >> ECM29_N Proteasome component ECM29, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 2.2e-06 0.056 329 382 .. 51 104 .. 18 117 .. 0.70 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 2.2e-06 ECM29_N 329 KLrslalqFinwvarhgs....ekelkkiapsllsglrkliesqgwpkpseknsseel 382 + ++ lqF++++ ++g+ ++e++++ap l+++++k+i ++g +k +++ ++ FUN_002218-T1 51 LVAQFQLQFFRHYNNKGPplydPNEMEAFAPALFTQILKSILNNGMSKDRQD----TQ 104 6778889999999999996555555******************999988333....22 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (127 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1193 (0.0467019); expected 510.9 (0.02) Passed bias filter: 824 (0.0322568); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1255.13 // Query: FUN_002219-T1 [L=129] Description: FUN_002219 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.18 11.4 0.0 0.18 11.4 0.0 1.1 1 DUF1464 Protein of unknown function (DUF1464) Domain annotation for each model (and alignments): >> DUF1464 Protein of unknown function (DUF1464) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 7.2e-06 0.18 7 68 .. 7 67 .. 5 111 .. 0.77 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 7.2e-06 DUF1464 7 ksydvvavdelgkvvlekeiptdevekdpsvlvkaieearadivalpSGyGlPlkkiselae 68 + ++++ +d+ +v k++pt++++ ++ ++ + + +++i a+p +Pl++ +++ FUN_002219-T1 7 NCFAILLIDDYHNVH-AKKVPTKLITSTATHMASCLLDIHPTIPAVPHPQQTPLHRPVKITI 67 5799******77765.678**********************************999887764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1123 (0.0439616); expected 510.9 (0.02) Passed bias filter: 883 (0.0345665); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1316.84 // Query: FUN_002220-T1 [L=239] Description: FUN_002220 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (239 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 493 (0.0192993); expected 510.9 (0.02) Passed bias filter: 390 (0.0152672); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.40s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2371.16 // Query: FUN_002224-T1 [L=132] Description: FUN_002224 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00091 19.8 5.7 2.5 8.7 0.2 3.9 4 bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal 0.0025 18.5 2.3 7.9 7.3 0.2 4.0 3 DUF7348 Domain of unknown function (DUF7348) ------ inclusion threshold ------ 0.015 14.1 0.0 0.3 9.8 0.0 2.0 2 Gp58 gp58-like protein 0.043 14.7 13.8 0.29 12.1 0.6 3.7 4 DUF2554 Protein of unknown function (DUF2554) 0.15 13.0 0.2 7.4 7.6 0.1 2.8 3 Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransfer 0.31 11.5 3.7 18 5.8 0.1 3.8 4 DUF1869 Domain of unknown function (DUF1869) 0.35 11.8 2.8 5.2 8.0 0.1 2.1 2 DUF2340 Uncharacterized conserved protein (DUF2340) 0.37 11.3 6.3 2.2 8.9 0.7 3.1 3 DUF4287 Domain of unknown function (DUF4287) 0.39 10.2 3.7 0.48 10.0 3.7 1.2 1 PDCD9 Mitochondrial 28S ribosomal protein S30 (PDC 4.7 8.2 9.1 6.8 7.6 0.8 3.5 4 DUF3761 Protein of unknown function (DUF3761) Domain annotation for each model (and alignments): >> bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0031 7.8 75 108 .. 13 46 .. 6 50 .. 0.82 2 ? 3.3 0.1 0.044 1.1e+02 90 108 .. 50 68 .. 47 71 .. 0.85 3 ! 8.7 0.2 0.00096 2.5 75 108 .. 68 101 .. 65 111 .. 0.85 4 ? 3.8 0.1 0.031 79 74 102 .. 100 128 .. 98 131 .. 0.86 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0031 bCoV_NSP3_N 75 ddyqglplefgasaetvrveeeeeedwlddtteq 108 + +g+ + ++ vrv+ e++ dw+ d e+ FUN_002224-T1 13 NKRDGVRVYHKRKSDGVRVNHEKKSDWVRDDHEK 46 5556777777788999************998775 PP == domain 2 score: 3.3 bits; conditional E-value: 0.044 bCoV_NSP3_N 90 tvrveeeeeedwlddtteq 108 +rv e++ dwl d e+ FUN_002224-T1 50 GLRVHHEKKSDWLRDDHEK 68 589**********998775 PP == domain 3 score: 8.7 bits; conditional E-value: 0.00096 bCoV_NSP3_N 75 ddyqglplefgasaetvrveeeeeedwlddtteq 108 +gl + ++ vrv+ e+ dw+ d e+ FUN_002224-T1 68 KKCDGLRVHHEKKSNGVRVDHEKTSDWVRDDHEK 101 56789999999999*************9887765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.031 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwl 102 e +gl ++ + vrv+ e++e w FUN_002224-T1 100 EKKSDGLSVDHEKKSHGVRVDHEKKERWD 128 5567899999999**************95 PP >> DUF7348 Domain of unknown function (DUF7348) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.1 0.27 7e+02 20 33 .. 16 31 .. 3 43 .. 0.57 2 ! 7.3 0.2 0.0031 7.9 18 24 .. 69 75 .. 33 101 .. 0.58 3 ? 4.3 0.1 0.026 67 19 45 .. 103 129 .. 88 132 .] 0.71 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.27 DUF7348 20 DGLrv..erdddgYrl 33 DG rv +r++dg r+ FUN_002224-T1 16 DGVRVyhKRKSDGVRV 31 5555533334555444 PP == domain 2 score: 7.3 bits; conditional E-value: 0.0031 DUF7348 18 dfDGLrv 24 ++DGLrv FUN_002224-T1 69 KCDGLRV 75 4555555 PP == domain 3 score: 4.3 bits; conditional E-value: 0.026 DUF7348 19 fDGLrverdddgYrletpdeertglse 45 DGL+v+++++ +++ +e+++ +e FUN_002224-T1 103 SDGLSVDHEKKSHGVRVDHEKKERWDE 129 6*****997776666655666665555 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.008 20 218 250 .. 4 36 .. 2 41 .. 0.89 2 ? 9.8 0.0 0.00012 0.3 154 250 .. 28 124 .. 27 126 .. 0.87 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.008 Gp58 218 ssGtteayeskLddlraeftrsnqGmrvelesk 250 s+G ye+k d++r + r + G+rv+ e k FUN_002224-T1 4 SDGVRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 6777888*********************99977 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00012 Gp58 154 GirreyqdadrqlsssyqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveles 249 G+r ++++ + +++ +Gl+ ++ + l+ + + gL +++++ +++ +ts+ + +e+k d+l ++ + + G+rv+ e FUN_002224-T1 28 GVRVNHEKKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKCDGLRVHHEKKSNGVRVDHEKTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEK 123 666666666667777889999999998888888899999999999999999999999999999999999999999999999999999999999887 PP Gp58 250 k 250 k FUN_002224-T1 124 K 124 6 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.61 1.6e+03 45 64 .. 4 23 .. 2 27 .. 0.77 2 ? 10.1 1.2 0.00046 1.2 35 64 .. 27 56 .. 11 60 .. 0.82 3 ? 12.1 0.6 0.00011 0.29 39 65 .. 53 79 .. 51 85 .. 0.89 4 ? 4.0 1.4 0.036 91 41 64 .. 88 111 .. 79 131 .. 0.54 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.61 DUF2554 45 sdelravaeesaeGlrehfy 64 sd +r e+ +G+r +++ FUN_002224-T1 4 SDGVRVHYENKRDGVRVYHK 23 78888888888899888775 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00046 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfy 64 + ++ he sd +r e+ +Glr h+ FUN_002224-T1 27 DGVRVNHEKKSDWVRDDHEKKFDGLRVHHE 56 456788**********************97 PP == domain 3 score: 12.1 bits; conditional E-value: 0.00011 DUF2554 39 lrheadsdelravaeesaeGlrehfyw 65 + he sd lr e+ +Glr h+ FUN_002224-T1 53 VHHEKKSDWLRDDHEKKCDGLRVHHEK 79 67**********************974 PP == domain 4 score: 4.0 bits; conditional E-value: 0.036 DUF2554 41 headsdelravaeesaeGlrehfy 64 he sd +r e+ ++Gl + FUN_002224-T1 88 HEKTSDWVRDDHEKKSDGLSVDHE 111 555555555555555555543332 PP >> Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransferase RsmF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.1 0.0029 7.4 22 70 .. 19 67 .. 10 79 .. 0.70 2 ? 2.6 0.0 0.099 2.5e+02 22 40 .. 74 92 .. 54 111 .. 0.64 3 ? 0.9 0.0 0.33 8.5e+02 25 44 .. 110 127 .. 89 132 .] 0.71 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0029 Methyltr_RsmF_N 22 aaleeplrkglRvNtlkiskeeleklaa..efelepvpwceeGfyleeeee 70 + +++ ++ g+RvN+ k k+++ + + +f+ +v + ++ +l++++e FUN_002224-T1 19 RVYHKRKSDGVRVNHEK--KSDWVRDDHekKFDGLRVHHEKKSDWLRDDHE 67 67889999*********..34433332224788888888888877777654 PP == domain 2 score: 2.6 bits; conditional E-value: 0.099 Methyltr_RsmF_N 22 aaleeplrkglRvNtlkis 40 + +e++++g+Rv + k+s FUN_002224-T1 74 RVHHEKKSNGVRVDHEKTS 92 3345666777777777743 PP == domain 3 score: 0.9 bits; conditional E-value: 0.33 Methyltr_RsmF_N 25 eeplrkglRvNtlkiskeel 44 +e++++g+Rv + k ke++ FUN_002224-T1 110 HEKKSHGVRVDHEK--KERW 127 57788999999999..5555 PP >> DUF1869 Domain of unknown function (DUF1869) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.4 3.7e+03 12 23 .. 3 14 .. 2 17 .. 0.81 2 ? -1.3 0.0 1.2 3.1e+03 12 23 .. 25 36 .. 20 46 .. 0.80 3 ? 5.8 0.1 0.007 18 11 23 .. 79 91 .. 71 100 .. 0.82 4 ? 3.4 0.1 0.039 1e+02 12 24 .. 102 114 .. 99 124 .. 0.72 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.4 DUF1869 12 knNGVSVDkdfe 23 k+ GV V ++ + FUN_002224-T1 3 KSDGVRVHYENK 14 789999999865 PP == domain 2 score: -1.3 bits; conditional E-value: 1.2 DUF1869 12 knNGVSVDkdfe 23 k+ GV V ++ + FUN_002224-T1 25 KSDGVRVNHEKK 36 789999998865 PP == domain 3 score: 5.8 bits; conditional E-value: 0.007 DUF1869 11 NknNGVSVDkdfe 23 k+NGV VD++ FUN_002224-T1 79 KKSNGVRVDHEKT 91 69*******9965 PP == domain 4 score: 3.4 bits; conditional E-value: 0.039 DUF1869 12 knNGVSVDkdfet 24 k+ G SVD++ ++ FUN_002224-T1 102 KSDGLSVDHEKKS 114 7788888888655 PP >> DUF2340 Uncharacterized conserved protein (DUF2340) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.002 5.2 55 99 .. 16 57 .. 2 70 .. 0.81 2 ? 4.2 0.3 0.03 77 63 98 .. 76 111 .. 66 116 .. 0.85 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.002 DUF2340 55 dtlKiytkahgskttnlvinldddeklilkdeektLaelgvenEt 99 d +++y h+ k+ +n ++ +++ +d+ek+ l v++E FUN_002224-T1 16 DGVRVY---HKRKSDGVRVNHEKKSDWVRDDHEKKFDGLRVHHEK 57 555665...6789999***********************999996 PP == domain 2 score: 4.2 bits; conditional E-value: 0.03 DUF2340 63 ahgskttnlvinldddeklilkdeektLaelgvenE 98 h++k++ ++ ++ +++ +d+ek+ l v++E FUN_002224-T1 76 HHEKKSNGVRVDHEKTSDWVRDDHEKKSDGLSVDHE 111 47888888899****99******9999999999888 PP >> DUF4287 Domain of unknown function (DUF4287) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.039 1e+02 28 45 .. 28 45 .. 18 46 .. 0.80 2 ? 8.9 0.7 0.00085 2.2 19 45 .. 38 67 .. 37 68 .. 0.85 3 ? 2.8 0.2 0.068 1.7e+02 28 45 .. 83 100 .. 74 101 .. 0.80 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.039 DUF4287 28 gllvkhgervawLkeehg 45 g v+h++ +w +++h+ FUN_002224-T1 28 GVRVNHEKKSDWVRDDHE 45 34489************6 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00085 DUF4287 19 eWlalveeggll...vkhgervawLkeehg 45 +W++ +e++++ v h++ +wL+++h+ FUN_002224-T1 38 DWVRDDHEKKFDglrVHHEKKSDWLRDDHE 67 6777777888888889*************6 PP == domain 3 score: 2.8 bits; conditional E-value: 0.068 DUF4287 28 gllvkhgervawLkeehg 45 g v h++ +w +++h+ FUN_002224-T1 83 GVRVDHEKTSDWVRDDHE 100 34489************6 PP >> PDCD9 Mitochondrial 28S ribosomal protein S30 (PDCD9) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 3.7 0.00019 0.48 201 272 .. 29 102 .. 19 126 .. 0.78 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 PDCD9 201 vdynpeveafWvrggviip.kghrrgrvealrfqiddrresverlvqyrgkphlqiRirkqla.efvpldaese 272 v +n e ++ Wvr + g r + ++ ++ dd+++ + l ++ +k + +R+++ + +v d+e++ FUN_002224-T1 29 VRVNHEKKSDWVRDDHEKKfDGLRVHHEKKSDWLRDDHEKKCDGLRVHHEKKSNGVRVDHEKTsDWVRDDHEKK 102 677888888899987654438889999999****************************9877658997777644 PP >> DUF3761 Protein of unknown function (DUF3761) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 0.66 1.7e+03 36 45 .. 5 14 .. 2 29 .. 0.59 2 ? 7.6 0.8 0.0027 6.8 22 57 .. 35 70 .. 24 77 .. 0.85 3 ? 4.3 0.3 0.03 76 23 49 .. 58 84 .. 55 91 .. 0.83 4 ? 2.4 0.4 0.11 2.9e+02 22 47 .. 90 115 .. 79 123 .. 0.80 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.66 DUF3761 36 DGqrvhkPer 45 DG rvh ++ FUN_002224-T1 5 DGVRVHYENK 14 6666665443 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0027 DUF3761 22 eesdLttedsyvnrDGqrvhkPeraksapagatarC 57 ++sd + +d+ DG rvh+ +++ +++ +C FUN_002224-T1 35 KKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKC 70 479999***************999988888888887 PP == domain 3 score: 4.3 bits; conditional E-value: 0.03 DUF3761 23 esdLttedsyvnrDGqrvhkPeraksa 49 +sd +d+ DG rvh+ ++++ + FUN_002224-T1 58 KSDWLRDDHEKKCDGLRVHHEKKSNGV 84 68888999999********98887765 PP == domain 4 score: 2.4 bits; conditional E-value: 0.11 DUF3761 22 eesdLttedsyvnrDGqrvhkPerak 47 + sd + +d+ +DG v + ++++ FUN_002224-T1 90 KTSDWVRDDHEKKSDGLSVDHEKKSH 115 4699999**********997766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 947 (0.0370718); expected 510.9 (0.02) Passed bias filter: 364 (0.0142494); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.30u 0.34s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1351.18 // Query: FUN_002225-T1 [L=143] Description: FUN_002225 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.77 10.2 4.4 1.1 9.7 0.1 3.1 3 KDM5_C-hel Lysine-specific demethylase 5, C-terminal helica Domain annotation for each model (and alignments): >> KDM5_C-hel Lysine-specific demethylase 5, C-terminal helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.2 0.12 3e+03 16 27 .. 58 69 .. 54 79 .. 0.69 2 ? 9.7 0.1 4.2e-05 1.1 15 40 .. 90 115 .. 88 121 .. 0.84 3 ? 0.4 0.0 0.033 8.4e+02 22 27 .. 130 135 .. 122 141 .. 0.82 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 0.12 KDM5_C-hel 16 lrrycVFSHdeL 27 l +c F H +L FUN_002225-T1 58 LSSHCSFFHGQL 69 556677766655 PP == domain 2 score: 9.7 bits; conditional E-value: 4.2e-05 KDM5_C-hel 15 klrrycVFSHdeLvckmaakaekLdv 40 +l +c FSH eL+ ++ + +L+ FUN_002225-T1 90 QLSPHCSFSHGELLPHLSFSHGQLSA 115 57789*********999888888765 PP == domain 3 score: 0.4 bits; conditional E-value: 0.033 KDM5_C-hel 22 FSHdeL 27 FSH eL FUN_002225-T1 130 FSHGEL 135 *****9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (143 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 263 (0.0102956); expected 510.9 (0.02) Passed bias filter: 180 (0.00704639); expected 510.9 (0.02) Passed Vit filter: 14 (0.000548052); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1444.73 // Query: FUN_002226-T1 [L=216] Description: FUN_002226 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0075 15.1 1.3 2.3 6.9 0.1 3.1 3 Gp58 gp58-like protein ------ inclusion threshold ------ 0.027 14.9 4.8 32 5.0 0.1 4.9 5 DUF1869 Domain of unknown function (DUF1869) 0.41 11.0 12.9 3.1 8.1 0.6 4.2 4 SH3_4 Bacterial SH3 domain 0.64 10.7 3.7 41 4.9 0.1 3.4 4 Pepdidase_M14_N Cytosolic carboxypeptidase N-terminal domain 1.6 9.2 2.1 94 3.5 0.1 3.5 3 ComGE Competence system putative prepilin ComGE 2.1 8.5 5.0 15 5.7 0.1 3.3 3 DUF3553 Protein of unknown function (DUF3553) 2.2 9.3 23.7 5.2 8.0 0.4 5.1 6 DUF2554 Protein of unknown function (DUF2554) 3.9 8.0 13.1 60 4.2 0.1 6.2 7 Beta-APP Beta-amyloid peptide (beta-APP) Domain annotation for each model (and alignments): >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.8 0.0 0.0064 20 227 256 .. 24 53 .. 6 71 .. 0.70 2 ? -0.5 0.0 0.13 4.1e+02 527 549 .. 77 99 .. 63 139 .. 0.55 3 ! 6.9 0.1 0.00071 2.3 187 247 .. 146 206 .. 141 215 .. 0.50 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0064 Gp58 227 skLddlraeftrsnqGmrveleskisGlqs 256 +k d+lra++ + G+rv e k G++ FUN_002226-T1 24 KKSDGLRADHKKKRDGVRVHHERKSNGVRV 53 566777777777777777777777666553 PP == domain 2 score: -0.5 bits; conditional E-value: 0.13 Gp58 527 ssdgidsaesgrfaGirifryas 549 +sdg+ +++++ aG+ + + ++ FUN_002226-T1 77 KSDGVRVHDEKKSAGVSVNHEKK 99 56666666666666665554443 PP == domain 3 score: 6.9 bits; conditional E-value: 0.00071 Gp58 187 GlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrvel 247 Gl+a+ + + g+ +++ + +++ + +G +e+k +++r ++ + + Gmrv l FUN_002226-T1 146 GLRADHKKKRDGVRVNHERKSNGVRVDQERKRDGLSVNHEKKSHGVRVDHEKKSDGMRVHL 206 4444444444454444444444444444555555555555555555555555555555555 PP >> DUF1869 Domain of unknown function (DUF1869) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.8 0.1 0.012 37 12 24 .. 47 59 .. 37 68 .. 0.82 2 ? 0.3 0.0 0.3 9.6e+02 12 23 .. 58 69 .. 56 73 .. 0.82 3 ? 1.3 0.1 0.15 4.7e+02 12 23 .. 88 99 .. 76 111 .. 0.84 4 ? 5.0 0.1 0.0099 32 11 23 .. 164 176 .. 155 185 .. 0.84 5 ? 1.2 0.0 0.16 5e+02 11 23 .. 186 198 .. 176 204 .. 0.75 Alignments for each domain: == domain 1 score: 4.8 bits; conditional E-value: 0.012 DUF1869 12 knNGVSVDkdfet 24 k+NGV VD++ ++ FUN_002226-T1 47 KSNGVRVDHERKR 59 89******99765 PP == domain 2 score: 0.3 bits; conditional E-value: 0.3 DUF1869 12 knNGVSVDkdfe 23 k G SVD++ + FUN_002226-T1 58 KRDGLSVDHEKK 69 678*****9976 PP == domain 3 score: 1.3 bits; conditional E-value: 0.15 DUF1869 12 knNGVSVDkdfe 23 k+ GVSV ++ + FUN_002226-T1 88 KSAGVSVNHEKK 99 788999998865 PP == domain 4 score: 5.0 bits; conditional E-value: 0.0099 DUF1869 11 NknNGVSVDkdfe 23 k+NGV VD++ + FUN_002226-T1 164 RKSNGVRVDQERK 176 599******9976 PP == domain 5 score: 1.2 bits; conditional E-value: 0.16 DUF1869 11 NknNGVSVDkdfe 23 k+ GV VD++ + FUN_002226-T1 186 KKSHGVRVDHEKK 198 6889999999865 PP >> SH3_4 Bacterial SH3 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.2 0.004 13 31 47 .. 12 28 .. 3 29 .. 0.87 2 ? 8.1 0.6 0.00098 3.1 16 47 .. 93 124 .. 87 125 .. 0.83 3 ? 3.1 0.1 0.036 1.2e+02 32 47 .. 131 146 .. 126 147 .. 0.87 4 ? -2.6 0.1 2.3 7.2e+03 33 47 .. 154 168 .. 152 168 .. 0.73 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.004 SH3_4 31 kckdnWcrvrDadGaeG 47 +++ +W+rv ++ +++G FUN_002226-T1 12 EKRSDWVRVDHKKKSDG 28 6788********99988 PP == domain 2 score: 8.1 bits; conditional E-value: 0.00098 SH3_4 16 avaaylepGvpvrvvkckdnWcrvrDadGaeG 47 +v+++ +++ + +++ +W+rv ++ +++G FUN_002226-T1 93 SVNHEKKRDGVGVHHEKRSDWVRVDHKKKSDG 124 7887777777777789999********99988 PP == domain 3 score: 3.1 bits; conditional E-value: 0.036 SH3_4 32 ckdnWcrvrDadGaeG 47 ++ +W+r+ ++ +++G FUN_002226-T1 131 KRSDWVRLDHKKKSDG 146 678********99988 PP == domain 4 score: -2.6 bits; conditional E-value: 2.3 SH3_4 33 kdnWcrvrDadGaeG 47 k++ +rv++ +++ G FUN_002226-T1 154 KRDGVRVNHERKSNG 168 556689999988876 PP >> Pepdidase_M14_N Cytosolic carboxypeptidase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.1 0.013 41 72 102 .. 10 40 .. 5 44 .. 0.87 2 ? 3.3 0.2 0.041 1.3e+02 73 102 .. 107 136 .. 99 138 .. 0.83 3 ? 3.7 0.1 0.031 99 73 102 .. 129 158 .. 125 162 .. 0.87 4 ? -2.8 0.0 3.1 9.9e+03 81 99 .. 170 188 .. 163 206 .. 0.61 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.013 Pepdidase_M14_N 72 asydreeWfrvpteyddgtltitltpeadtv 102 + r++W rv+ + + + l+ +++ ++d v FUN_002226-T1 10 RHEKRSDWVRVDHKKKSDGLRADHKKKRDGV 40 56789*******************9998876 PP == domain 2 score: 3.3 bits; conditional E-value: 0.041 Pepdidase_M14_N 73 sydreeWfrvpteyddgtltitltpeadtv 102 + r++W rv+ + + + ++++++ +d v FUN_002226-T1 107 HEKRSDWVRVDHKKKSDGMRVHHEKRSDWV 136 67899******9999999999998877765 PP == domain 3 score: 3.7 bits; conditional E-value: 0.031 Pepdidase_M14_N 73 sydreeWfrvpteyddgtltitltpeadtv 102 + r++W r++ + + + l+ +++ ++d v FUN_002226-T1 129 HEKRSDWVRLDHKKKSDGLRADHKKKRDGV 158 5789*******************9998876 PP == domain 4 score: -2.8 bits; conditional E-value: 3.1 Pepdidase_M14_N 81 rvpteyddgtltitltpea 99 rv+ e + + l+++++ ++ FUN_002226-T1 170 RVDQERKRDGLSVNHEKKS 188 4444444455555554443 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.0 0.051 1.6e+02 55 77 .. 47 69 .. 38 71 .. 0.84 2 ? -0.1 0.1 0.4 1.3e+03 58 77 .. 80 99 .. 76 111 .. 0.63 3 ? 3.5 0.1 0.029 94 55 77 .. 165 187 .. 157 207 .. 0.90 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.051 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv v +++ ++l+v +++k FUN_002226-T1 47 KSNGVRVDHERKRDGLSVDHEKK 69 56999999999999999999876 PP == domain 2 score: -0.1 bits; conditional E-value: 0.4 ComGE 58 Gvevtvkenqeelivlesgk 77 Gv v+ ++++ +++v +++k FUN_002226-T1 80 GVRVHDEKKSAGVSVNHEKK 99 56666666666666666554 PP == domain 3 score: 3.5 bits; conditional E-value: 0.029 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv v +++ ++l+v +++k FUN_002226-T1 165 KSNGVRVDQERKRDGLSVNHEKK 187 5699***9999999999999987 PP >> DUF3553 Protein of unknown function (DUF3553) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.1 0.0048 15 4 15 .. 6 17 .. 4 18 .. 0.94 2 ? -0.9 0.2 0.58 1.9e+03 4 15 .. 102 113 .. 100 114 .. 0.89 3 ? 3.0 0.1 0.035 1.1e+02 4 15 .. 124 135 .. 122 136 .. 0.94 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0048 DUF3553 4 GdlVrhPkqpdW 15 G+ Vrh k+ dW FUN_002226-T1 6 GMRVRHEKRSDW 17 9*********** PP == domain 2 score: -0.9 bits; conditional E-value: 0.58 DUF3553 4 GdlVrhPkqpdW 15 G V h k+ dW FUN_002226-T1 102 GVGVHHEKRSDW 113 7789******** PP == domain 3 score: 3.0 bits; conditional E-value: 0.035 DUF3553 4 GdlVrhPkqpdW 15 G+ V h k+ dW FUN_002226-T1 124 GMRVHHEKRSDW 135 9*********** PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.4 0.0016 5.2 36 64 .. 6 34 .. 2 39 .. 0.86 2 ? 5.6 2.3 0.0094 30 39 65 .. 20 46 .. 11 57 .. 0.86 3 ? 0.8 0.2 0.3 9.4e+02 38 63 .. 41 66 .. 35 78 .. 0.75 4 ? 5.4 1.0 0.011 34 38 64 .. 104 130 .. 80 136 .. 0.89 5 ? 4.7 0.3 0.017 55 38 64 .. 137 163 .. 131 171 .. 0.86 6 ? 4.5 0.4 0.021 67 38 64 .. 181 207 .. 175 215 .. 0.80 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0016 DUF2554 36 dhqlrheadsdelravaeesaeGlrehfy 64 + ++rhe sd +r ++ ++Glr ++ FUN_002226-T1 6 GMRVRHEKRSDWVRVDHKKKSDGLRADHK 34 6789*********************9886 PP == domain 2 score: 5.6 bits; conditional E-value: 0.0094 DUF2554 39 lrheadsdelravaeesaeGlrehfyw 65 + h+ sd lra ++ +G+r h+ FUN_002226-T1 20 VDHKKKSDGLRADHKKKRDGVRVHHER 46 568999******************974 PP == domain 3 score: 0.8 bits; conditional E-value: 0.3 DUF2554 38 qlrheadsdelravaeesaeGlrehf 63 ++ he s+ +r e +Gl + FUN_002226-T1 41 RVHHERKSNGVRVDHERKRDGLSVDH 66 56788888888888888888886555 PP == domain 4 score: 5.4 bits; conditional E-value: 0.011 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he sd +r ++ ++G+r h+ FUN_002226-T1 104 GVHHEKRSDWVRVDHKKKSDGMRVHHE 130 578**********************97 PP == domain 5 score: 4.7 bits; conditional E-value: 0.017 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 +l h+ sd lra ++ +G+r + FUN_002226-T1 137 RLDHKKKSDGLRADHKKKRDGVRVNHE 163 588999***************998775 PP == domain 6 score: 4.5 bits; conditional E-value: 0.021 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he s +r e+ ++G+r h FUN_002226-T1 181 SVNHEKKSHGVRVDHEKKSDGMRVHLE 207 578999999999999999999999964 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.071 2.3e+02 2 14 .. 2 14 .. 1 16 [. 0.92 2 ? 0.8 0.1 0.21 6.6e+02 1 13 [. 45 57 .. 45 70 .. 0.69 3 ? 4.2 0.1 0.019 60 1 14 [. 86 99 .. 86 100 .. 0.90 4 ? -0.4 0.0 0.49 1.6e+03 8 14 .. 104 110 .. 101 111 .. 0.83 5 ? 2.4 0.0 0.067 2.1e+02 3 14 .. 121 132 .. 119 134 .. 0.86 6 ? -0.4 0.0 0.5 1.6e+03 1 14 [. 174 187 .. 174 191 .. 0.82 7 ? -0.5 0.1 0.53 1.7e+03 1 14 [. 185 198 .. 185 199 .. 0.83 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.071 Beta-APP 2 RQSAsyEVYHEKl 14 R+S + V HEK+ FUN_002226-T1 2 RKSDGMRVRHEKR 14 8999********8 PP == domain 2 score: 0.8 bits; conditional E-value: 0.21 Beta-APP 1 eRQSAsyEVYHEK 13 eR+S + V HE+ FUN_002226-T1 45 ERKSNGVRVDHER 57 6777777777775 PP == domain 3 score: 4.2 bits; conditional E-value: 0.019 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V HEK+ FUN_002226-T1 86 EKKSAGVSVNHEKK 99 689*********96 PP == domain 4 score: -0.4 bits; conditional E-value: 0.49 Beta-APP 8 EVYHEKl 14 V HEK+ FUN_002226-T1 104 GVHHEKR 110 599***8 PP == domain 5 score: 2.4 bits; conditional E-value: 0.067 Beta-APP 3 QSAsyEVYHEKl 14 +S + V HEK+ FUN_002226-T1 121 KSDGMRVHHEKR 132 688999*****8 PP == domain 6 score: -0.4 bits; conditional E-value: 0.5 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+ + V HEK+ FUN_002226-T1 174 ERKRDGLSVNHEKK 187 577778899***96 PP == domain 7 score: -0.5 bits; conditional E-value: 0.53 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002226-T1 185 EKKSHGVRVDHEKK 198 56788999****96 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (216 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 586 (0.0229399); expected 510.9 (0.02) Passed bias filter: 191 (0.007477); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2111.06 // Query: FUN_002227-T1 [L=75] Description: FUN_002227 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.17 12.0 0.1 0.2 11.7 0.1 1.1 1 MRP-S31 Mitochondrial 28S ribosomal protein S31 Domain annotation for each model (and alignments): >> MRP-S31 Mitochondrial 28S ribosomal protein S31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 7.8e-06 0.2 276 297 .. 8 29 .. 2 34 .. 0.91 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 7.8e-06 MRP-S31 276 NpylsvkqKkeHieWfrdyfee 297 N + + k+K eHi W dyf e FUN_002227-T1 8 NRFEASKNKSEHILWRYDYFGE 29 889999**************76 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (75 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 603 (0.0236054); expected 510.9 (0.02) Passed bias filter: 440 (0.0172245); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 755.72 // Query: FUN_002228-T1 [L=927] Description: FUN_002228 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-44 146.8 16.8 7.6e-05 23.3 0.0 11.8 11 Ank Ankyrin repeat 1.2e-40 138.4 4.4 1.9e-10 41.6 0.3 5.8 5 Ank_2 Ankyrin repeats (3 copies) 2.4e-37 126.6 7.0 0.00014 22.5 0.1 9.9 10 Ank_4 Ankyrin repeats (many copies) 1.6e-27 95.8 13.9 0.00039 21.2 0.1 9.1 8 Ank_5 Ankyrin repeats (many copies) 7.2e-20 69.3 5.5 0.044 14.8 0.0 10.9 10 Ank_3 Ankyrin repeat 0.00064 20.0 0.1 0.86 9.8 0.0 3.5 4 Ank_KRIT1 KRIT1 ankyrin-repeats domain ------ inclusion threshold ------ 0.035 14.6 0.0 0.089 13.3 0.0 1.7 1 Mab-21 Mab-21 protein nucleotidyltransferase domain Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.0 0.0005 1.8 1 30 [. 43 73 .. 43 76 .. 0.90 2 ! 18.4 0.0 7.4e-07 0.0027 4 30 .. 92 118 .. 92 120 .. 0.88 3 ! 10.8 0.0 0.00021 0.75 15 33 .] 150 168 .. 125 168 .. 0.89 4 ! 18.8 0.3 5.6e-07 0.002 1 32 [. 172 204 .. 172 205 .. 0.91 5 ! 13.4 0.0 3e-05 0.11 3 32 .. 208 237 .. 206 238 .. 0.94 6 ! 23.3 0.0 2.1e-08 7.6e-05 2 32 .. 240 270 .. 239 271 .. 0.91 7 ! 20.3 0.1 1.8e-07 0.00066 3 33 .] 274 310 .. 272 310 .. 0.87 8 ! 7.2 0.0 0.0028 10 2 32 .. 312 346 .. 311 347 .. 0.73 9 ? 4.9 0.0 0.016 57 16 32 .. 414 430 .. 409 431 .. 0.89 10 ! 11.5 0.0 0.00012 0.42 2 32 .. 433 471 .. 432 472 .. 0.88 11 ! 8.3 0.0 0.0012 4.5 1 21 [. 473 493 .. 473 503 .. 0.86 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0005 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvna 30 +G ++L +A+ ++++v+ LLk +Ad+n FUN_002228-T1 43 YGLSALCMAVkAFQSPSLVEKLLKMNADPNF 73 599*******98899********779***95 PP == domain 2 score: 18.4 bits; conditional E-value: 7.4e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvna 30 +PLH+Aa h+ + k LL+ GAd+n FUN_002228-T1 92 SPLHVAAWLRHPGITKVLLDGGADPNT 118 6******999999******547***95 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00021 Ank 15 levvklLLkhGAdvnardk 33 l+v+klL+++GAdv a+d+ FUN_002228-T1 150 LDVMKLLIDNGADVTAVDN 168 67******88******997 PP == domain 4 score: 18.8 bits; conditional E-value: 5.6e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA.dvnard 32 dG + LH+A + gh+ +v++LL+ A dvn+r+ FUN_002228-T1 172 DGTSLLHMATQGGHVLIVNYLLSLRAlDVNCRN 204 7999******************668879**998 PP == domain 5 score: 13.4 bits; conditional E-value: 3e-05 Ank 3 nTPLHlAaraghlevvklL.LkhGAdvnard 32 TPL++A r+++ e+++ L L hGA +n rd FUN_002228-T1 208 ETPLMIALREDRQELLEDLpL-HGAHPNSRD 237 7********************.8******98 PP == domain 6 score: 23.3 bits; conditional E-value: 2.1e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH+A+ + +++ v++L+++ Advn +d FUN_002228-T1 240 GCTALHIAVGRTCVKSVEILIQNSADVNMKD 270 9********778899******878*****99 PP == domain 7 score: 20.3 bits; conditional E-value: 1.8e-07 Ank 3 nTPLHlAaragh......levvklLLkhGAdvnardk 33 +T+LH+A+r ++ ++v+k LL+++Advn+ d+ FUN_002228-T1 274 RTALHVASRLNNsssksnVKVMKSLLSNNADVNVADN 310 7*******6666677778********879*****997 PP == domain 8 score: 7.2 bits; conditional E-value: 0.0028 Ank 2 GnTPLHlAaragh.....levvklLLkhGAdvnard 32 G+ PLHl + ++ + ++ LL+h Ad+ ++d FUN_002228-T1 312 GRRPLHLTVI-DNkdtldMTALERLLEHDADPSLTD 346 888****993.4424744444466**999***9988 PP == domain 9 score: 4.9 bits; conditional E-value: 0.016 Ank 16 evvklLLkhGAdvnard 32 ++++ L+++G+d+n++d FUN_002228-T1 414 KIIRELVEAGVDINCQD 430 699****99******98 PP == domain 10 score: 11.5 bits; conditional E-value: 0.00012 Ank 2 GnTPLHlAa.ragh.......levvklLLkhGAdvnard 32 G T+LH + r+g+ + + LL++GAd nard FUN_002228-T1 433 GSTCLHHTVgRKGRtsshlkfSDFTRVLLDAGADRNARD 471 99*****99977777778999********88*******9 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0012 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP H+Aa+ + + +++L FUN_002228-T1 473 DGNTPAHIAAEGEDADQLRML 493 8*********87778877777 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 4.1e-08 0.00015 18 88 .. 33 118 .. 22 120 .. 0.77 2 ! 41.6 0.3 5.3e-14 1.9e-10 10 90 .] 150 237 .. 145 237 .. 0.89 3 ! 30.6 0.2 1.4e-10 5.2e-07 12 72 .. 222 285 .. 219 290 .. 0.88 4 ! 17.2 0.2 2.1e-06 0.0078 8 64 .. 290 353 .. 283 376 .. 0.65 5 ! 27.7 0.0 1.1e-09 4.2e-06 11 80 .. 414 494 .. 409 508 .. 0.82 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 4.1e-08 Ank_2 18 egadanlqdkngetaLhlAak.nghleivklLlehgad....vndnn.............grtaLhyAaesghleivklLlekgadina 88 e++++n++++ g +aL +A+k ++ +v+ Ll+ +ad + ++Lh+Aa+ +h i k+Ll+ gad+n+ FUN_002228-T1 33 EKQNPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADpnfeS---YigkflgtrktekpSGSPLHVAAWLRHPGITKVLLDGGADPNT 118 678999999************5567899*99999766633440...24444455555555558******************99****97 PP == domain 2 score: 41.6 bits; conditional E-value: 5.3e-14 Ank_2 10 lelvklLl.egadanlqdk...ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+++klL+ +gad+ +d+ +g++ Lh+A + gh+ iv +Ll+ dvn + + +t+L++A +++++e ++ L +ga++n++d FUN_002228-T1 150 LDVMKLLIdNGADVTAVDNtktDGTSLLHMATQGGHVLIVNYLLSLRaLDVNcrNIHEETPLMIALREDRQELLEDLPLHGAHPNSRD 237 6899*********997777799**********************9654667776888********************989***99987 PP == domain 3 score: 30.6 bits; conditional E-value: 1.4e-10 Ank_2 12 lvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesgh 72 l++ L +ga +n++d g taLh+A+ + ++ v++L++++advn d++ rtaLh+A++ ++ FUN_002228-T1 222 LLEDLPlHGAHPNSRDMAGCTALHIAVGRTCVKSVEILIQNSADVNmkDSSCRTALHVASRLNN 285 56666448999999888***********************99999999999********99876 PP == domain 4 score: 17.2 bits; conditional E-value: 2.1e-06 Ank_2 8 gnlelvklLl.egadanlqdkngetaLhlAakng..hlei..vklLlehgadvn..dnngrtaL 64 n +++k Ll ++ad+n+ d++g+ +Lhl + + l++ ++ Lleh+ad d r +L FUN_002228-T1 290 SNVKVMKSLLsNNADVNVADNQGRRPLHLTVIDNkdTLDMtaLERLLEHDADPSltDAIERMPL 353 3456778888788888887778888888777765233344546888887544334444455555 PP == domain 5 score: 27.7 bits; conditional E-value: 1.1e-09 Ank_2 11 elvklLl.egadanlqdkngetaLhlAakng.....hlei...vklLlehgadvn..dnngrtaLhyAaesghleivklLl 80 +++++L+ g+d+n+qd +g t Lh+ + + hl++ ++Ll+ gad n d +g+t+ h+Aae + +++L+ FUN_002228-T1 414 KIIRELVeAGVDINCQDIEGSTCLHHTVGRKgrtssHLKFsdfTRVLLDAGADRNarDIDGNTPAHIAAEGEDADQLRMLA 494 4899*********************9998543555455435549*****999988999***********988888888887 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.6 5.9e+03 22 49 .. 36 64 .. 31 71 .. 0.75 2 ? 4.1 0.0 0.025 93 1 40 [. 94 133 .. 93 136 .. 0.84 3 ! 22.5 0.1 3.9e-08 0.00014 7 50 .] 147 193 .. 144 193 .. 0.86 4 ! 10.1 0.0 0.00031 1.1 8 42 .. 184 219 .. 184 226 .. 0.86 5 ! 11.5 0.1 0.00012 0.43 4 39 .. 214 249 .. 211 251 .. 0.86 6 ! 20.9 0.0 1.3e-07 0.00047 9 39 .. 252 282 .. 249 288 .. 0.90 7 ! 16.4 0.0 3.4e-06 0.012 7 35 .. 289 317 .. 286 320 .. 0.94 8 ? 2.9 0.0 0.061 2.2e+02 11 34 .. 330 353 .. 328 360 .. 0.84 9 ! 17.1 0.0 2e-06 0.0072 11 36 .. 414 439 .. 413 449 .. 0.91 10 ! 21.7 0.0 7.5e-08 0.00027 13 49 .. 457 493 .. 446 494 .. 0.93 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.6 Ank_4 22 dinatdgngetaLhfAa.sngnlevlklL 49 ++n ++ +g +aL +A+ ++ +++ ++ L FUN_002228-T1 36 NPNFVNSYGLSALCMAVkAFQSPSLVEKL 64 66777999999999999666666666666 PP == domain 2 score: 4.1 bits; conditional E-value: 0.025 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasn 40 lh+Aa h + k Ll+ gad+n++ n t+L ++ n FUN_002228-T1 94 LHVAAWLRHPGITKVLLDGGADPNTVaF-NSLTPLLLVLTN 133 6888888999999*************65.589999887765 PP == domain 3 score: 22.5 bits; conditional E-value: 3.9e-08 Ank_4 7 sghlellklLlengadinat.d..gngetaLhfAasngnlevlklLl 50 + l++ klL++ngad+ a+ + +g + Lh+A ++g++ ++ +Ll FUN_002228-T1 147 QAALDVMKLLIDNGADVTAVdNtkTDGTSLLHMATQGGHVLIVNYLL 193 5669************9998434466999**************9997 PP == domain 4 score: 10.1 bits; conditional E-value: 0.00031 Ank_4 8 ghlellklLlen.gadinatdgngetaLhfAasngn 42 gh+ ++ +Ll+ +d+n+++ et+L +A++ + FUN_002228-T1 184 GHVLIVNYLLSLrALDVNCRNIHEETPLMIALREDR 219 79999*****9956*****************98665 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00012 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAas 39 A + ++ell+ L +ga++n +d g taLh+A+ FUN_002228-T1 214 ALREDRQELLEDLPLHGAHPNSRDMAGCTALHIAVG 249 666788899999999*******************95 PP == domain 6 score: 20.9 bits; conditional E-value: 1.3e-07 Ank_4 9 hlellklLlengadinatdgngetaLhfAas 39 +++ ++ L++n ad+n+ d +++taLh A++ FUN_002228-T1 252 CVKSVEILIQNSADVNMKDSSCRTALHVASR 282 7899*************************86 PP == domain 7 score: 16.4 bits; conditional E-value: 3.4e-06 Ank_4 7 sghlellklLlengadinatdgngetaLh 35 ++++++ k+Ll+n ad+n d++g+ +Lh FUN_002228-T1 289 KSNVKVMKSLLSNNADVNVADNQGRRPLH 317 7899************************* PP == domain 8 score: 2.9 bits; conditional E-value: 0.061 Ank_4 11 ellklLlengadinatdgngetaL 34 +l++Lle++ad+ td + +L FUN_002228-T1 330 TALERLLEHDADPSLTDAIERMPL 353 5799*********99988777666 PP == domain 9 score: 17.1 bits; conditional E-value: 2e-06 Ank_4 11 ellklLlengadinatdgngetaLhf 36 ++++ L+e g+din++d +g t+Lh+ FUN_002228-T1 414 KIIRELVEAGVDINCQDIEGSTCLHH 439 57999********************7 PP == domain 10 score: 21.7 bits; conditional E-value: 7.5e-08 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklL 49 + Ll+ gad na+d +g+t+ h+Aa +++ + l++L FUN_002228-T1 457 TRVLLDAGADRNARDIDGNTPAHIAAEGEDADQLRML 493 689*****************************99998 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.00088 3.2 8 43 .. 36 72 .. 31 73 .. 0.88 2 ! 18.8 0.0 6.3e-07 0.0023 18 53 .. 92 127 .. 86 129 .. 0.95 3 ? 4.2 0.0 0.024 88 26 47 .. 147 168 .. 145 171 .. 0.88 4 ! 13.3 0.2 3.3e-05 0.12 14 56 .] 171 214 .. 166 214 .. 0.89 5 ! 21.2 0.1 1.1e-07 0.00039 7 56 .] 233 280 .. 228 280 .. 0.84 6 ? 5.2 0.0 0.011 41 20 54 .. 283 317 .. 283 318 .. 0.81 7 ! 7.8 0.2 0.0017 6.3 1 54 [. 298 354 .. 298 355 .. 0.81 8 ! 20.1 0.1 2.4e-07 0.00088 1 56 [] 419 481 .. 419 481 .. 0.89 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00088 Ank_5 8 dlnrldgegytpLhvAak.ygaleivrlLlangvdln 43 ++n + +g +L++A+k ++ +v++Ll+ ++d+n FUN_002228-T1 36 NPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADPN 72 677779999*********************8888876 PP == domain 2 score: 18.8 bits; conditional E-value: 6.3e-07 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 pLhvAa+ +++ i ++Ll+ g+d+n+ ++ ltpl FUN_002228-T1 92 SPLHVAAWLRHPGITKVLLDGGADPNTVAFNSLTPL 127 79********************************98 PP == domain 3 score: 4.2 bits; conditional E-value: 0.024 Ank_5 26 ygaleivrlLlangvdlnlkde 47 + al++++lL++ng+d+++ d+ FUN_002228-T1 147 QAALDVMKLLIDNGADVTAVDN 168 6799**************9997 PP == domain 4 score: 13.3 bits; conditional E-value: 3.3e-05 Ank_5 14 gegytpLhvAakygaleivrlLl.angvdlnlkdeegltpldlA 56 ++g+ Lh+A +g+ iv++Ll + d+n+++ + +tpl +A FUN_002228-T1 171 TDGTSLLHMATQGGHVLIVNYLLsLRALDVNCRNIHEETPLMIA 214 457799**********************************9776 PP == domain 5 score: 21.2 bits; conditional E-value: 1.1e-07 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + + g+ t+Lh+A+ + + v++L+ n +d+n+kd+++ t+l++A FUN_002228-T1 233 PNSRDMAGC--TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVA 280 344444445..************************************998 PP == domain 6 score: 5.2 bits; conditional E-value: 0.011 Ank_5 20 LhvAakygaleivrlLlangvdlnlkdeegltpld 54 L++ +++ + +++ Ll n++d+n+ d++g pl+ FUN_002228-T1 283 LNNSSSKSNVKVMKSLLSNNADVNVADNQGRRPLH 317 56677888888999999999999999999977776 PP == domain 7 score: 7.8 bits; conditional E-value: 0.0017 Ank_5 1 LlengpadlnrldgegytpLhvAakygal....eivrlLlangvdlnlkdeegltpld 54 Ll n ad+n d+ g pLh+ + + + +++Ll++++d+ l+d+ +pl FUN_002228-T1 298 LLSNN-ADVNVADNQGRRPLHLTVIDNKDtldmTALERLLEHDADPSLTDAIERMPLS 354 67776.99999999999*****999887622225699*************98888886 PP == domain 8 score: 20.1 bits; conditional E-value: 2.4e-07 Ank_5 1 LlengpadlnrldgegytpLhvAak.yga.......leivrlLlangvdlnlkdeegltpldlA 56 L+e+g +d+n++d eg t+Lh+ + +g+ +++ r+Ll+ g+d n++d +g+tp ++A FUN_002228-T1 419 LVEAG-VDINCQDIEGSTCLHHTVGrKGRtsshlkfSDFTRVLLDAGADRNARDIDGNTPAHIA 481 89999.88888888999********999955555556899**********************98 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.19 6.9e+02 8 30 .. 50 72 .. 43 73 .. 0.72 2 ! 9.2 0.0 0.00082 3 4 30 .. 92 117 .. 90 118 .. 0.95 3 ? 4.4 0.0 0.031 1.1e+02 13 30 .. 148 164 .. 144 165 .. 0.84 4 ! 8.3 0.1 0.0017 6.2 4 30 .. 175 201 .. 172 202 .. 0.87 5 ? 2.6 0.0 0.12 4.5e+02 3 21 .. 208 226 .. 206 235 .. 0.76 6 ! 14.8 0.0 1.2e-05 0.044 2 31 .] 240 268 .. 239 268 .. 0.96 7 ! 10.1 0.0 0.00043 1.6 3 31 .] 274 307 .. 274 307 .. 0.93 8 ? 2.3 0.0 0.14 5.3e+02 2 29 .. 312 342 .. 311 344 .. 0.72 9 ? 1.4 0.0 0.29 1.1e+03 17 31 .] 415 428 .. 410 428 .. 0.89 10 ? 3.4 0.0 0.064 2.3e+02 1 14 [. 473 486 .. 473 497 .. 0.81 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.19 Ank_3 8 lAarngrle.ivklLleklgadin 30 +A++ + + +v+ Ll+ ++ad+n FUN_002228-T1 50 MAVKAFQSPsLVEKLLK-MNADPN 72 55555555559******.****99 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00082 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa ++ i k+Ll+ gad+n FUN_002228-T1 92 SPLHVAAWLRHPGITKVLLD-GGADPN 117 8*******************.*****9 PP == domain 3 score: 4.4 bits; conditional E-value: 0.031 Ank_3 13 grleivklLleklgadin 30 + l+++klL++ +gad+ FUN_002228-T1 148 AALDVMKLLID-NGADVT 164 6789*******.****85 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0017 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 ++Lh+A g++ iv +Ll + d+n FUN_002228-T1 175 SLLHMATQGGHVLIVNYLLSLRALDVN 201 89*****************98777777 PP == domain 5 score: 2.6 bits; conditional E-value: 0.12 Ank_3 3 ntpLhlAarngrleivklL 21 +tpL++A r +r e+++ L FUN_002228-T1 208 ETPLMIALREDRQELLEDL 226 8********9987777655 PP == domain 6 score: 14.8 bits; conditional E-value: 1.2e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+t+Lh+A+ +++ v+ L++ + ad+n+ FUN_002228-T1 240 GCTALHIAVGRTCVKSVEILIQ-NSADVNM 268 89************99******.*****95 PP == domain 7 score: 10.1 bits; conditional E-value: 0.00043 Ank_3 3 ntpLhlAarngrl......eivklLleklgadina 31 +t+Lh+A r ++ +++k Ll ++ad+n+ FUN_002228-T1 274 RTALHVASRLNNSssksnvKVMKSLLS-NNADVNV 307 79***********99998889******.*****95 PP == domain 8 score: 2.3 bits; conditional E-value: 0.14 Ank_3 2 gntpLh.lAarngrl...eivklLleklgadi 29 g+ pLh +++ n + ++++ Lle + ad+ FUN_002228-T1 312 GRRPLHlTVIDNKDTldmTALERLLE-HDADP 342 88999955555555564445******.99998 PP == domain 9 score: 1.4 bits; conditional E-value: 0.29 Ank_3 17 ivklLleklgadina 31 i++ L+e g+din+ FUN_002228-T1 415 IIRELVE-AGVDINC 428 89*****.9****96 PP == domain 10 score: 3.4 bits; conditional E-value: 0.064 Ank_3 1 dgntpLhlAarngr 14 dgntp h+Aa+ + FUN_002228-T1 473 DGNTPAHIAAEGED 486 79*******98665 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.048 1.7e+02 42 78 .. 85 121 .. 60 133 .. 0.72 2 ! 9.8 0.0 0.00024 0.86 42 92 .. 169 214 .. 157 226 .. 0.72 3 ? 2.3 0.0 0.047 1.7e+02 87 142 .. 242 297 .. 232 304 .. 0.82 4 ? -3.6 0.0 3.1 1.1e+04 109 128 .. 464 484 .. 457 493 .. 0.63 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.048 Ank_KRIT1 42 ekvddpes.lvaAakgGheevlqlLlalGkadpdPepv 78 ++ + + s l+ Aa+ h ++++Ll+ G+adp+ + FUN_002228-T1 85 KTEKPSGSpLHVAAWLRHPGITKVLLD-GGADPNTVAF 121 4444343459****************8.6688885444 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00024 Ank_KRIT1 42 ekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAa 92 +k+d + l++A++gGh ++++Ll l d + + +++ +tPl+ a FUN_002228-T1 169 TKTDGTSLLHMATQGGHVLIVNYLLSLRALDVNCRNIHE-----ETPLMIA 214 344445558999999999999999999999998666654.....4666555 PP == domain 3 score: 2.3 bits; conditional E-value: 0.047 Ank_KRIT1 87 tPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgenweeeeklLke 142 t l a+Gr +k +++l++++ ++ +t l +a + ++++ + + k++k+ FUN_002228-T1 242 TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVASRLNNSSSKSNVKVMKS 297 667789***********9976654455559999******99999999999999987 PP == domain 4 score: -3.6 bits; conditional E-value: 3.1 Ank_KRIT1 109 efdptrr.lkgetyleiarer 128 + d++ r + g+t++ ia+e FUN_002228-T1 464 GADRNARdIDGNTPAHIAAEG 484 345554448888888888764 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 2.4e-05 0.089 3 138 .. 749 891 .. 747 911 .. 0.67 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.4e-05 Mab-21 3 enlkvlsPdeFdlvlkLklpeneeiivkedpggpgyvelkltrsg..esndnsrkellsqwleeaegylsaaKvlsrfqslvekalkklekeievn 96 e++k +PdeFd++ +L+ + + +++ y+ l +++ s d++ ke ++++l + ++ ls +K++ f l +a l+++++ + FUN_002228-T1 749 EETKLWKPDEFDFMMELTQL--------KGHSRLEYAGLSRSSNTtvISLDDEMKEMWREFL-K-DDCLSLEKLRDYFVLLTWRAGFSLQRQKY-K 833 789999***********922........3333355555555552235555679999999999.6.899**999999999999999888766555.3 PP Mab-21 97 detlklsykrk.......gpavt.....vaietseeq..............ysVdlvpaielkasWpk 138 + +ls ++ p v+ v ++Vdl++++++++ Wp FUN_002228-T1 834 NLSFNLS--QQsggtgssHPLVRmssvgV-------LlhvqwhgydytsldIDVDLTLSVPFSD-WPV 891 3333333..33568866633333323222.......122333346688899*************.996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (927 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 702 (0.0274809); expected 510.9 (0.02) Passed bias filter: 601 (0.0235271); expected 510.9 (0.02) Passed Vit filter: 49 (0.00191818); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.39u 0.41s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 8849.83 // Query: FUN_002229-T1 [L=178] Description: FUN_002229 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 407 (0.0159327); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1801.73 // Query: FUN_002230-T1 [L=124] Description: FUN_002230 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-18 65.9 0.4 5.8e-18 65.6 0.4 1.2 1 Histone Core histone H2A/H2B/H3/H4 domain 2e-08 34.5 0.0 2.5e-08 34.1 0.0 1.2 1 Histone_ABTB Histone domain in ABTB family protein 0.0034 18.1 0.0 0.0069 17.1 0.0 1.5 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.051 14.1 0.3 0.06 13.8 0.3 1.2 1 YscO-like YscO-like protein 0.25 12.4 0.0 0.48 11.5 0.0 1.4 1 TFIID_20kDa Transcription initiation factor TFIID subunit Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.6 0.4 1.1e-21 5.8e-18 7 88 .] 22 99 .. 16 99 .. 0.94 Alignments for each domain: == domain 1 score: 65.6 bits; conditional E-value: 1.1e-21 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ +++++++++ ++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_002230-T1 22 AETAKRRRGKRKESYAIYKYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.0 4.9e-12 2.5e-08 23 91 .. 53 123 .. 37 124 .] 0.86 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 4.9e-12 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_002230-T1 53 ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 123 7888888899999999************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.3e-06 0.0069 10 65 .] 42 97 .. 41 97 .. 0.95 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 CBFD_NFYB_HMF 10 rImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_002230-T1 42 KVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 97 899***88888.*****************************************9996 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.3 1.2e-05 0.06 38 113 .. 25 99 .. 6 119 .. 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.2e-05 YscO-like 38 lakleaerdkvlkhkkaKlqqlrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 ++++ +r + + K + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_002230-T1 25 AKRRRGKRKESYAIY--KYKVLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 333333344444444..44445542569******************************************9988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.4e-05 0.48 8 60 .. 43 95 .. 41 99 .. 0.93 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.4e-05 TFIID_20kDa 8 LvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_002230-T1 43 VLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 95 5899***********************************************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 820 (0.0321002); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1281.34 // Query: FUN_002231-T1 [L=106] Description: FUN_002231 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-08 35.2 0.1 2.1e-08 34.7 0.1 1.3 1 CENP-T_C Centromere kinetochore component CENP-T histon 5.3e-06 27.0 0.1 7.4e-06 26.5 0.1 1.3 1 TAF TATA box binding protein associated factor (TA 8.4e-05 23.4 0.2 9.6e-05 23.2 0.2 1.3 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00018 22.3 0.1 0.0003 21.6 0.1 1.5 1 CENP-S CENP-S protein 0.00023 21.9 0.2 0.0004 21.1 0.1 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 0.0016 19.0 0.0 0.002 18.7 0.0 1.1 1 TFIID-31kDa Transcription initiation factor IID, 31kD subu ------ inclusion threshold ------ 0.02 15.4 0.1 0.03 14.8 0.1 1.3 1 Bromo_TP Bromodomain associated 0.087 13.1 0.1 0.11 12.8 0.1 1.0 1 UPF0137 Uncharacterised protein family (UPF0137) 0.11 13.0 0.1 0.13 12.7 0.1 1.2 1 TAFII28 hTAFII28-like protein conserved region Domain annotation for each model (and alignments): >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.7 0.1 7.2e-12 2.1e-08 19 80 .. 40 99 .. 23 103 .. 0.82 Alignments for each domain: == domain 1 score: 34.7 bits; conditional E-value: 7.2e-12 CENP-T_C 19 rfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 r+ar++ + +++s e +++ f+e v D +y++HA+RKt+ Dv+ lkRq++ FUN_002231-T1 40 RLARRG--GVKRISDLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR 99 344442..356788888888889999**********************************75 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.1 2.6e-09 7.4e-06 4 66 .] 33 95 .. 30 95 .. 0.91 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 2.6e-09 TAF 4 ipkesvkvvAeslGianLsdeaaalLaedveyrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 i+k +++ +A G++ +sd ++ ++ l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_002231-T1 33 ITKPAIRRLARRGGVKRISDLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 95 5777889999999999999999999999999999***************************98 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.2 3.4e-08 9.6e-05 53 87 .. 61 95 .. 20 96 .. 0.89 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 3.4e-08 Histone 53 avedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 +++ +l+ + ++A +++haKR+T+t+ D+ A++ FUN_002231-T1 61 VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALK 95 5789**************************99986 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 1.1e-07 0.0003 42 73 .. 66 97 .. 30 100 .. 0.82 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.1e-07 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_002231-T1 66 LENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 97 78999********************9998885 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.1 1.4e-07 0.0004 8 65 .] 38 94 .. 31 94 .. 0.83 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 1.4e-07 CBFD_NFYB_HMF 8 vkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++r+ + ++++is+ e ++ f+e v + A+ +++++krKT++a ++ A+ FUN_002231-T1 38 IRRLARRG-GVKRISDLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYAL 94 66666666.7777777777777778999*************************98876 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 7.1e-07 0.002 15 70 .. 42 97 .. 34 102 .. 0.80 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 7.1e-07 TFIID-31kDa 15 LkslgieeyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 + g++ +++ + ++ + + +v++dA +y ehak+k++++ dv A++ + FUN_002231-T1 42 ARRGGVKRISDLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 97 555666666666666666777778999***********************999865 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.1 1.1e-05 0.03 34 70 .. 60 96 .. 43 102 .. 0.89 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.1e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_002231-T1 60 GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKR 96 67788999999************************98 PP >> UPF0137 Uncharacterised protein family (UPF0137) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 3.7e-05 0.11 141 216 .. 26 101 .. 21 104 .. 0.92 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3.7e-05 UPF0137 141 lkaeveslPrqavYtLasRegslekkeeiienynGetktelleiirktfPlldtdrRqknlsekllellakllklv 216 l+ +++ + + a+ La R g + i e+ +G k l ++ir + +++ +R++ + ++ l++ + + FUN_002231-T1 26 LRDNIQGITKPAIRRLARRGGVKRISDLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTL 101 7889999*************9999999999*********************************9999999877665 PP >> TAFII28 hTAFII28-like protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.1 4.5e-05 0.13 22 72 .. 33 83 .. 29 97 .. 0.87 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 4.5e-05 TAFII28 22 lnkaaikklvnsvlgqsvsqnvaivvaglaKvFvgeiveeAlevqeewges 72 + k ai++l+ + + +s+ + +g+ KvF +++ A++ e+ + + FUN_002231-T1 33 ITKPAIRRLARRGGVKRISDLIYEETRGVLKVFLENVIRDAVTYTEHAKRK 83 78999*******9999**************************999987655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (106 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 556 (0.0217655); expected 510.9 (0.02) Passed bias filter: 460 (0.0180074); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1088.70 // Query: FUN_002232-T1 [L=181] Description: FUN_002232 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (181 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 671 (0.0262674); expected 510.9 (0.02) Passed bias filter: 429 (0.0167939); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 1790.52 // Query: FUN_002233-T1 [L=203] Description: FUN_002233 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-05 24.8 0.0 5.6e-05 24.2 0.0 1.2 1 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family ------ inclusion threshold ------ 0.098 13.4 0.1 28 5.5 0.1 2.4 2 DUF6616 Family of unknown function (DUF6616) Domain annotation for each model (and alignments): >> Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 4.4e-09 5.6e-05 2 125 .. 58 168 .. 57 172 .. 0.74 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 4.4e-09 Lipase_GDSL_2 2 lGDSiTaGygdtggdrswpgwlarllaerlgadvvnnlgisGattallrllerld.allrlkpdlvvillGtNDlgrgvpparaaannlealvrrl 96 lGDSi + +r p + l+ + + v n+gi+G+t+ + +l r+ + + + +l GtN+l + p++ + a + +++ l FUN_002233-T1 58 LGDSIIK-----NIERFAPKY-FTLFPAST----VLNAGIPGDTV--EAILYRVLhMSFPSTVTCISLLCGTNNLSSHSPAT-ISAT-VMEILFVL 139 7888888.....556777777.66666666....778********..555555553655566699*********86666655.5566.99****** PP Lipase_GDSL_2 97 raaapgarvlglgplpvgpppppdarrln 125 r+++p + + + + lp ++ + + r++n FUN_002233-T1 140 RQKCPTCVIHLFPNLPRFDQFFSNVRATN 168 *******8888888888887777766655 PP >> DUF6616 Family of unknown function (DUF6616) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.0026 34 17 65 .. 29 77 .. 25 84 .. 0.86 2 ? 5.5 0.1 0.0022 28 64 99 .. 148 183 .. 145 195 .. 0.80 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.0026 DUF6616 17 lskeeReaflekvgeaiselaelGvevlalgendeetdkradyrffavw 65 l +++Rea +++++ +l++ ++ev+ lg + +r + ++f+ + FUN_002233-T1 29 LGPKRREAKATQIESIQRKLSNDRAEVILLGDSIIKNIERFAPKYFTLF 77 67889**************************988888888888888765 PP == domain 2 score: 5.5 bits; conditional E-value: 0.0022 DUF6616 64 vwrvpskeaadaleagieasgWydYFeqvnaageae 99 + +p+ d++ ++++a++ y YF n+ ++ FUN_002233-T1 148 IHLFPNLPRFDQFFSNVRATNTYIYFHVKNFFPSSY 183 6678899999*****************999866555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 878 (0.0343707); expected 510.9 (0.02) Passed bias filter: 698 (0.0273243); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.39s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 1959.17 // Query: FUN_002234-T1 [L=99] Description: FUN_002234 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 546 (0.021374); expected 510.9 (0.02) Passed bias filter: 353 (0.0138188); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1017.70 // Query: FUN_002235-T1 [L=195] Description: FUN_002235 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 13.0 0.1 5.4 7.9 0.0 2.1 2 Gluconate_2-dh3 Gluconate 2-dehydrogenase subunit 3 Domain annotation for each model (and alignments): >> Gluconate_2-dh3 Gluconate 2-dehydrogenase subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.0054 1.4e+02 46 112 .. 3 68 .. 1 75 [. 0.77 2 ? 7.9 0.0 0.00021 5.4 45 85 .. 150 190 .. 110 194 .. 0.88 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.0054 Gluconate_2-dh3 46 eafragLaaldaeakkrygksFaeltpeqqdalLkalekgakakeeeeawkakaevrffnllkeltl 112 e++ ++L++ +++++ g sF el ++ q ++ ++++++ + ++++a a ++ f+++++ +l FUN_002235-T1 3 ENLESELNKAKDHIQFLKGSSFEELVAQFQLQFFRHYNNKGPPLYDPNEMEAFA-PALFTQILKSIL 68 67888999999999999********************99977644434455544.777777666655 PP == domain 2 score: 7.9 bits; conditional E-value: 0.00021 Gluconate_2-dh3 45 qeafragLaaldaeakkrygksFaeltpeqqdalLkalekg 85 q+ ++++L ++++ +++ + ++l+p+q ++ L++l + FUN_002235-T1 150 QQKMHQALGNMKKPFMNQLSIPILDLSPKQLQEALRQLRQV 190 8999********************************99875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (195 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1123 (0.0439616); expected 510.9 (0.02) Passed bias filter: 862 (0.0337444); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.25u 0.41s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1970.14 // Query: FUN_002236-T1 [L=248] Description: FUN_002236 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (248 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1113 (0.0435702); expected 510.9 (0.02) Passed bias filter: 682 (0.026698); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2444.02 // Query: FUN_002237-T1 [L=62] Description: FUN_002237 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (62 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 541 (0.0211783); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 623.49 // Query: FUN_002242-T1 [L=73] Description: FUN_002242 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (73 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 408 (0.0159718); expected 510.9 (0.02) Passed bias filter: 366 (0.0143277); expected 510.9 (0.02) Passed Vit filter: 17 (0.000665492); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.22u 0.39s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 755.95 // Query: FUN_002243-T1 [L=122] Description: FUN_002243 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.086 13.5 1.2 0.86 10.3 0.1 2.1 2 SdrD_B SdrD B-like domain 0.61 11.0 15.9 4.2 8.3 1.5 3.1 3 DUF2554 Protein of unknown function (DUF2554) 1.7 9.0 4.4 8.4 6.8 0.5 3.0 2 Herpes_UL52 Herpesviridae UL52/UL70 DNA primase 1.8 9.9 8.7 60 5.0 8.7 2.4 1 DUF1764 Eukaryotic protein of unknown function (DUF1764) 4.7 7.9 8.9 15 6.3 2.1 3.5 4 DUF7510 Family of unknown function (DUF7510) 8.7 7.0 9.1 49 4.6 8.9 2.0 1 PCC_BT Propionyl-coenzyme A carboxylase BT domain Domain annotation for each model (and alignments): >> SdrD_B SdrD B-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.1 0.06 2.5e+02 5 39 .. 9 43 .. 6 54 .. 0.77 2 ? 10.3 0.1 0.0002 0.86 4 37 .. 63 96 .. 60 109 .. 0.85 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.06 SdrD_B 5 dfVweDanknGiqdagekGisgvtvtLkdesgevv 39 +V + + + + d+ ek +g tv+ +++s++v FUN_002243-T1 9 VRVHHEKRSDWVRDDHEKKSDGLTVHQEKKSDRVR 43 57888888899999999999999999988887765 PP == domain 2 score: 10.3 bits; conditional E-value: 0.0002 SdrD_B 4 GdfVweDanknGiqdagekGisgvtvtLkdesge 37 G +V++ + +G++ + ekG +gvtv+ +++s+ FUN_002243-T1 63 GVRVYHEKKSEGVKVDHEKGSDGVTVHHEKKSDW 96 678***********************99777765 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 1.6 0.0065 28 34 66 .. 6 38 .. 1 47 [. 0.82 2 ? 6.3 1.0 0.0044 19 41 64 .. 46 69 .. 36 82 .. 0.57 3 ? 8.3 1.5 0.001 4.2 38 64 .. 87 113 .. 81 121 .. 0.85 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0065 DUF2554 34 tvdhqlrheadsdelravaeesaeGlrehfywq 66 + + ++ he sd +r e+ ++Gl h + FUN_002243-T1 6 SDGVRVHHEKRSDWVRDDHEKKSDGLTVHQEKK 38 5567889*******************9997654 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0044 DUF2554 41 headsdelravaeesaeGlrehfy 64 h+ s +r ee +eG+r ++ FUN_002243-T1 46 HKKKSHGVRVDHEEKSEGVRVYHE 69 555555566666666666665543 PP == domain 3 score: 8.3 bits; conditional E-value: 0.001 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he sd +r e ++G+r h+ FUN_002243-T1 87 TVHHEKKSDWVRLQHERKSDGVRVHHE 113 578**********************96 PP >> Herpes_UL52 Herpesviridae UL52/UL70 DNA primase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.5 0.002 8.4 8 45 .. 42 74 .. 21 79 .. 0.77 2 ? 2.9 0.1 0.034 1.5e+02 24 37 .. 97 110 .. 80 116 .. 0.82 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.002 Herpes_UL52 8 ilvqlkrsrrgrnfsClnikhrhksnnvrvfldlrvdk 45 + v++k+++ +++ h+ ks++vrv+ + ++++ FUN_002243-T1 42 VRVDHKKKS-----HGVRVDHEEKSEGVRVYHEKKSEG 74 445555442.....236999*********998888776 PP == domain 2 score: 2.9 bits; conditional E-value: 0.034 Herpes_UL52 24 lnikhrhksnnvrv 37 ++ +h++ks++vrv FUN_002243-T1 97 VRLQHERKSDGVRV 110 57899999999998 PP >> DUF1764 Eukaryotic protein of unknown function (DUF1764) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 8.7 0.014 60 9 85 .. 37 81 .. 2 120 .. 0.44 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.014 DUF1764 9 eeideifsekkkkkkekkkeekeekekkkkkkkkkkkkkkkeeeekfedsk.ekkkrkktedGlpvYte...eeLgigkad 85 ++ d++ ++kkk+ + + ++++++G++vY+e e +++++++ FUN_002243-T1 37 KKSDRVRVDHKKKS------------------------------------HgVRVDHEEKSEGVRVYHEkksEGVKVDHEK 81 11222221111111....................................1123333334444444443222222222222 PP >> DUF7510 Family of unknown function (DUF7510) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 0.3 1.3e+03 88 100 .. 4 16 .. 2 21 .. 0.76 2 ? 6.3 2.1 0.0036 15 72 107 .. 32 67 .. 12 77 .. 0.78 3 ? 2.1 0.1 0.072 3.1e+02 75 105 .. 68 98 .. 67 101 .. 0.69 4 ? 2.1 0.1 0.069 3e+02 87 100 .. 102 115 .. 90 117 .. 0.80 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.3 DUF7510 88 etadGfrivHpep 100 + +dG+r++H+ FUN_002243-T1 4 RKSDGVRVHHEKR 16 5789***999865 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0036 DUF7510 72 spYqsardseaaeGvsetadGfrivHpepvtdvrll 107 + q++++++ + ++ ++G+r+ H+e + vr++ FUN_002243-T1 32 TVHQEKKSDRVRVDHKKKSHGVRVDHEEKSEGVRVY 67 45667777777788899999*********9999997 PP == domain 3 score: 2.1 bits; conditional E-value: 0.072 DUF7510 75 qsardseaaeGvsetadGfrivHpepvtdvr 105 ++++++ + ++ +dG++++H+ + vr FUN_002243-T1 68 HEKKSEGVKVDHEKGSDGVTVHHEKKSDWVR 98 5556666666677889999999988776666 PP == domain 4 score: 2.1 bits; conditional E-value: 0.069 DUF7510 87 setadGfrivHpep 100 ++ +dG+r++H+e+ FUN_002243-T1 102 ERKSDGVRVHHEEE 115 67899******986 PP >> PCC_BT Propionyl-coenzyme A carboxylase BT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 8.9 0.012 49 32 101 .. 17 89 .. 3 115 .. 0.54 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.012 PCC_BT 32 kdwvvvvkgedek...vtveveedgdevevevdgesvevssdwklgdpliratvdgepvtvqv..ekraggfrLr 101 +dwv +++++k +tv+ e+++d v+v+++ +s+ v+ d + + +r+ ++++ v+v ek + g++++ FUN_002243-T1 17 SDWVR--DDHEKKsdgLTVHQEKKSDRVRVDHKKKSHGVRVDHEEKSEGVRVYHEKKSEGVKVdhEKGSDGVTVH 89 55553..22222223356666666666666666666666666666665555555555555555322222224333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (122 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1166 (0.0456449); expected 510.9 (0.02) Passed bias filter: 395 (0.0154629); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 1253.01 // Query: FUN_002244-T1 [L=171] Description: FUN_002244 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.021 14.8 0.1 0.067 13.2 0.1 1.7 2 SlipAM Surface lipoprotein assembly modifier 0.046 14.6 8.2 1.3 9.9 0.8 3.5 3 DUF2554 Protein of unknown function (DUF2554) 0.15 12.4 1.6 6 7.1 0.4 2.4 3 BamHI Restriction endonuclease BamHI 0.27 11.7 2.1 19 5.8 0.1 3.1 3 PH_FT_C PH domain found in tandem in fungal proteins 0.44 11.0 5.7 12 6.4 0.6 3.8 4 ComGE Competence system putative prepilin ComGE 3 8.5 4.2 8.2 7.1 0.3 2.8 3 Ig_ZP2_3rd Zona pellucida sperm-binding protein 2, Ig-like d 6.3 8.2 12.9 5.6 8.3 5.3 2.3 2 DUF1764 Eukaryotic protein of unknown function (DUF1764) Domain annotation for each model (and alignments): >> SlipAM Surface lipoprotein assembly modifier # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.1 1.8e-05 0.067 74 126 .. 45 110 .. 38 152 .. 0.79 2 ? 2.4 0.0 0.035 1.3e+02 87 126 .. 102 143 .. 98 166 .. 0.67 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 1.8e-05 SlipAM 74 dnkkyddlstraglGigyknaktdvsllPfyekrfy.............gndryskasGvrlelns 126 d+kk+d ++ r ++G++ +++k+ ++++++ek+++ g d+ +k++Gvr+++++ FUN_002244-T1 45 DEKKSDVFTIRKSNGVRVHDEKNSNGVRVLHEKKSAvvrvnhdkksdgvGVDHEKKSNGVRIHHEK 110 78999******************************9999988888888877777777766665543 PP == domain 2 score: 2.4 bits; conditional E-value: 0.035 SlipAM 87 lGigyknaktdvsllPfyekrfy..gndryskasGvrlelns 126 +G++ +++k+ ++++++e+++ ++ +k+ Gv++++++ FUN_002244-T1 102 NGVRIHHEKKRDGVRVYHERKSDgmRVNHEKKSEGVKVDHEK 143 677778888888888888888874433455555566666554 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.38 1.4e+03 28 60 .. 51 83 .. 30 90 .. 0.68 2 ? 5.7 1.6 0.0078 28 36 58 .. 114 136 .. 75 141 .. 0.62 3 ? 9.9 0.8 0.00037 1.3 37 65 .. 137 165 .. 133 171 .] 0.81 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.38 DUF2554 28 efvwvktvdhqlrheadsdelravaeesaeGlr 60 f k+ + ++ e +s+ +r e+ + +r FUN_002244-T1 51 VFTIRKSNGVRVHDEKNSNGVRVLHEKKSAVVR 83 455556666666777777777777766555555 PP == domain 2 score: 5.7 bits; conditional E-value: 0.0078 DUF2554 36 dhqlrheadsdelravaeesaeG 58 + ++ he sd +r e+ +eG FUN_002244-T1 114 GVRVYHERKSDGMRVNHEKKSEG 136 23344555555555555555555 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00037 DUF2554 37 hqlrheadsdelravaeesaeGlrehfyw 65 ++ he sd +r e ++G+r h+ FUN_002244-T1 137 VKVDHEKKSDGVRLQHERKSDGVRVHHEK 165 5788**********************963 PP >> BamHI Restriction endonuclease BamHI # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 0.86 3.1e+03 40 56 .. 49 62 .. 35 72 .. 0.66 2 ? 7.1 0.4 0.0016 6 19 55 .. 69 105 .. 54 111 .. 0.83 3 ? 4.3 0.0 0.012 43 25 59 .. 108 142 .. 105 163 .. 0.76 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 0.86 BamHI 40 edsfiinptrkGnGvkp 56 +d f+ +rk nGv+ FUN_002244-T1 49 SDVFT---IRKSNGVRV 62 44444...578888764 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0016 BamHI 19 elesilkeveraiklvvwprdedsfiinptrkGnGvk 55 + +l+e + a+ v + +++d ++ +k nGv+ FUN_002244-T1 69 NGVRVLHEKKSAVVRVNHDKKSDGVGVDHEKKSNGVR 105 4456789999**************************8 PP == domain 3 score: 4.3 bits; conditional E-value: 0.012 BamHI 25 keveraiklvvwprdedsfiinptrkGnGvkpike 59 +e +r v + r++d + +n +k +Gvk +e FUN_002244-T1 108 HEKKRDGVRVYHERKSDGMRVNHEKKSEGVKVDHE 142 55555666789999999999999999999996554 PP >> PH_FT_C PH domain found in tandem in fungal proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.023 82 7 31 .. 61 85 .. 39 93 .. 0.86 2 ? 5.8 0.1 0.0051 19 6 31 .. 104 129 .. 99 139 .. 0.85 3 ? 0.2 0.0 0.28 1e+03 19 33 .. 139 153 .. 129 162 .. 0.62 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.023 PH_FT_C 7 eIlddgyehaLrvyrdrksgavRLe 31 +++d++ rv++++ks +vR++ FUN_002244-T1 61 RVHDEKNSNGVRVLHEKKSAVVRVN 85 6788888999999999999999986 PP == domain 2 score: 5.8 bits; conditional E-value: 0.0051 PH_FT_C 6 geIlddgyehaLrvyrdrksgavRLe 31 +I++++ + rvy++rks+++R++ FUN_002244-T1 104 VRIHHEKKRDGVRVYHERKSDGMRVN 129 68999999999*************87 PP == domain 3 score: 0.2 bits; conditional E-value: 0.28 PH_FT_C 19 vyrdrksgavRLeas 33 v +++ks++vRL+ FUN_002244-T1 139 VDHEKKSDGVRLQHE 153 445666777777643 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.4 0.6 0.0032 12 44 78 .. 56 79 .. 23 91 .. 0.59 2 ? 4.1 0.1 0.017 62 55 77 .. 100 122 .. 80 128 .. 0.86 3 ? -0.9 0.0 0.6 2.2e+03 58 77 .. 125 144 .. 122 150 .. 0.81 4 ? -0.2 0.0 0.37 1.3e+03 57 77 .. 146 166 .. 135 170 .. 0.69 Alignments for each domain: == domain 1 score: 6.4 bits; conditional E-value: 0.0032 ComGE 44 qmAvqtkqdeLslNGvevtvkenqeelivlesgke 78 + NGv v+ ++n++++ vl+++k FUN_002244-T1 56 KS-----------NGVRVHDEKNSNGVRVLHEKKS 79 33...........5666666666666666665543 PP == domain 2 score: 4.1 bits; conditional E-value: 0.017 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv ++ +++ +++ v+++ k FUN_002244-T1 100 KSNGVRIHHEKKRDGVRVYHERK 122 45999999999999999999876 PP == domain 3 score: -0.9 bits; conditional E-value: 0.6 ComGE 58 Gvevtvkenqeelivlesgk 77 G+ v+ ++++e++ v +++k FUN_002244-T1 125 GMRVNHEKKSEGVKVDHEKK 144 78888888888888888776 PP == domain 4 score: -0.2 bits; conditional E-value: 0.37 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv ++ +++++++ v ++++ FUN_002244-T1 146 DGVRLQHERKSDGVRVHHEKE 166 577777777777777777765 PP >> Ig_ZP2_3rd Zona pellucida sperm-binding protein 2, Ig-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.3 0.0023 8.2 20 58 .. 35 74 .. 26 84 .. 0.80 2 ? 1.4 0.1 0.13 4.8e+02 41 55 .. 100 114 .. 83 139 .. 0.62 3 ? -0.5 0.0 0.51 1.9e+03 35 52 .. 146 155 .. 126 170 .. 0.48 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0023 Ig_ZP2_3rd 20 vsvenkniplsqlqengialetknGlrlhisksllksk.v 58 v+ ++kni+ ++ +++ +++++nG+r+h +k+ ++ FUN_002244-T1 35 VTQKKKNIKDDEKKSDVFTIRKSNGVRVHDEKNSNGVRvL 74 6667899**********************99987766643 PP == domain 2 score: 1.4 bits; conditional E-value: 0.13 Ig_ZP2_3rd 41 tknGlrlhisksllk 55 ++nG+r+h +k+ FUN_002244-T1 100 KSNGVRIHHEKKRDG 114 345777777665433 PP == domain 3 score: -0.5 bits; conditional E-value: 0.51 Ig_ZP2_3rd 35 ngialetknGlrlhisks 52 + G+rl+ +++ FUN_002244-T1 146 D--------GVRLQHERK 155 2........444433333 PP >> DUF1764 Eukaryotic protein of unknown function (DUF1764) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.3 5.3 0.0015 5.6 2 76 .. 39 120 .. 37 130 .. 0.59 2 ? 4.4 1.4 0.026 93 41 78 .. 130 166 .. 120 170 .. 0.60 Alignments for each domain: == domain 1 score: 8.3 bits; conditional E-value: 0.0015 DUF1764 2 kkekkkkeeideifsekkkkkkekkkeeke.......ekekkkkkkkkkkkkkkkeeeekfedsk.ekkkrkktedGlpvYte 76 kk+ k++e+ ++f +k++ + + e+++ e +k + +++kk++ ++ ++s+ + +++k+ dG++vY+e FUN_002244-T1 39 KKNIKDDEKKSDVFTIRKSNGVRVHDEKNSngvrvlhE-KKSAVVRVNHDKKSDGVGVDHEKKSNgVRIHHEKKRDGVRVYHE 120 56667788888888888887777777666666766532.22222222222222222222222222467899999*******97 PP == domain 2 score: 4.4 bits; conditional E-value: 0.026 DUF1764 41 kkkkkkkkkeeeekfedskekkkrkktedGlpvYteee 78 ++kk++ k ++ek +d + ++++++dG++v++e+e FUN_002244-T1 130 HEKKSEGVKVDHEKKSDG-VRLQHERKSDGVRVHHEKE 166 333333333333333333.477888999***9999887 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (171 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 836 (0.0327266); expected 510.9 (0.02) Passed bias filter: 314 (0.012292); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.30u 0.41s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 1698.62 // Query: FUN_002245-T1 [L=658] Description: FUN_002245 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.79 10.6 6.1 3.2 8.7 4.7 2.8 3 U-box_ZFPL1 ZFPL1-like, U-box domain Domain annotation for each model (and alignments): >> U-box_ZFPL1 ZFPL1-like, U-box domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 0.67 1.7e+04 14 36 .. 176 201 .. 167 209 .. 0.59 2 ? 8.7 4.7 0.00012 3.2 5 33 .. 312 337 .. 305 351 .. 0.76 3 ? -1.2 0.1 0.15 3.9e+03 2 18 .. 341 357 .. 339 359 .. 0.80 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 0.67 U-box_ZFPL1 14 gsettRLgC...Lhvlhtsclvshlk 36 ++e tRL+ ++ l t+c + + + FUN_002245-T1 176 NKESTRLSSditFDQLVTQCQTALFR 201 45677776322255666666655555 PP == domain 2 score: 8.7 bits; conditional E-value: 0.00012 U-box_ZFPL1 5 CqavleegagsettRLgCLhvlhtsclvs 33 C++ +g + +RLgC h +h scl s FUN_002245-T1 312 CNNCT---NGGDFVRLGCYHTFHVSCLPS 337 44443...45689**************65 PP == domain 3 score: -1.2 bits; conditional E-value: 0.15 U-box_ZFPL1 2 CslCqavleegagsett 18 C+ C++ le+ +++t FUN_002245-T1 341 CTICKEPLEQMISKKVT 357 789*****998777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (658 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1885 (0.0737913); expected 510.9 (0.02) Passed bias filter: 864 (0.0338227); expected 510.9 (0.02) Passed Vit filter: 68 (0.00266197); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 6383.36 // Query: FUN_002246-T1 [L=160] Description: FUN_002246 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 15.7 0.4 0.021 15.1 0.3 1.4 1 Rep_fac-A_C Replication factor-A C terminal domain 0.039 13.5 0.5 0.056 13.0 0.5 1.4 1 MGAT2 N-acetylglucosaminyltransferase II (MGAT2) 0.16 12.6 2.2 0.32 11.6 2.2 1.5 1 FYVE FYVE zinc finger 0.34 11.2 4.7 3.3 8.0 0.4 2.5 2 Zn_ribbon_CLPX_N CLPX-like, zinc ribbon domain 0.67 10.0 3.0 1.7 8.7 3.0 1.8 1 EcdD_BsdD_detox EcdD/BsdD phenolic detoxification 2.3 8.5 4.8 6.4 7.1 2.8 2.7 2 Ribosomal_S27e Ribosomal protein S27 Domain annotation for each model (and alignments): >> Rep_fac-A_C Replication factor-A C terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.3 4.9e-06 0.021 20 80 .. 54 116 .. 34 127 .. 0.73 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 4.9e-06 Rep_fac-A_C 20 ACpsedCnkKvvee.edgewrCekCd..keveepky.ryilsikvsDstgqlwvtlFneaaekll 80 C +C +Kv++ ++ +C++C +++++++ ry + D l++t+Fne+ +k++ FUN_002246-T1 54 KCV--KCARKVLQPsATLVVHCDRCGyfMRTADCEKrRYATIVVELDGKKPLFLTVFNEVLNKVV 116 466..9******99455679*****833344556651555555557*************988876 PP >> MGAT2 N-acetylglucosaminyltransferase II (MGAT2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.5 1.3e-05 0.056 265 308 .. 54 97 .. 44 128 .. 0.81 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.3e-05 MGAT2 265 kClskklkvlvlkaprvlhlgeCGlhkkkkeCekeeaiekleel 308 kC++ + kvl +a+ v+h+ CG ++ +Cek++ ++ + el FUN_002246-T1 54 KCVKCARKVLQPSATLVVHCDRCGYFMRTADCEKRRYATIVVEL 97 89999****************************99988876665 PP >> FYVE FYVE zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 2.2 7.6e-05 0.32 7 59 .. 51 129 .. 45 131 .. 0.74 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7.6e-05 FYVE 7 evkeCseCkkeF..tllrrrhHCrkCGkvfC.skCsskkisll.......................eelkeekpvrvCd 59 + +C +C+++ + HC +CG + ++C +++++++ e+l++ + rvC+ FUN_002246-T1 51 RFLKCVKCARKVlqPSATLVVHCDRCGYFMRtADCEKRRYATIvveldgkkplfltvfnevlnkvvEDLETATDSRVCE 129 567899999999532457789*******985277887777666777777777777777777777777777888888887 PP >> Zn_ribbon_CLPX_N CLPX-like, zinc ribbon domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.4 0.00078 3.3 22 31 .. 50 59 .. 41 67 .. 0.83 2 ? 5.1 4.6 0.0064 27 3 33 .. 53 79 .. 52 82 .. 0.84 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.00078 Zn_ribbon_CLPX_N 22 tRFvkCekCn 31 RF+kC kC FUN_002246-T1 50 ERFLKCVKCA 59 6********7 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0064 Zn_ribbon_CLPX_N 3 lnCpkCG.kplksvetfvsstRFvkCekCnhl 33 l+C kC k+l++ t+v v+C+ C ++ FUN_002246-T1 53 LKCVKCArKVLQPSATLV-----VHCDRCGYF 79 799999846788889999.....******988 PP >> EcdD_BsdD_detox EcdD/BsdD phenolic detoxification # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 3.0 0.0004 1.7 27 45 .. 70 88 .. 51 92 .. 0.89 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0004 EcdD_BsdD_detox 27 vlqCerClytWRstEParr 45 v++C+rC y R++ ++r FUN_002246-T1 70 VVHCDRCGYFMRTADCEKR 88 89***********998877 PP >> Ribosomal_S27e Ribosomal protein S27 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 0.59 2.5e+03 17 25 .. 7 15 .. 3 16 .. 0.79 2 ? 7.1 2.8 0.0015 6.4 8 35 .. 53 79 .. 50 89 .. 0.81 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.59 Ribosomal_S27e 17 tvvFshaat 25 +vFs+a t FUN_002246-T1 7 STVFSSAFT 15 79***9976 PP == domain 2 score: 7.1 bits; conditional E-value: 0.0015 Ribosomal_S27e 8 vkCpdCenetvvFshaatvvkCisCgkv 35 kC +C + +v +a vv C Cg FUN_002246-T1 53 LKCVKCAR-KVLQPSATLVVHCDRCGYF 79 48999975.5777888899999999965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (160 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1674 (0.0655314); expected 510.9 (0.02) Passed bias filter: 946 (0.0370327); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.27u 0.44s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 1595.37 // Query: FUN_002247-T1 [L=267] Description: FUN_002247 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.3e-46 157.9 0.0 4.6e-46 157.5 0.0 1.1 1 rva_4 Integrase core domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 157.5 0.0 1.8e-50 4.6e-46 43 188 .. 32 179 .. 26 184 .. 0.96 Alignments for each domain: == domain 1 score: 157.5 bits; conditional E-value: 1.8e-50 rva_4 43 stnnrastvlkqflkavkkyg..lPsrvrsdkggenvkvallmnllrGlerssvitGrsvhnqrierlWrdvfkkvvsvfyslftaledseildid 136 tnn +stvl+ f +av++ g Psr+r d g+en++v+ m +rG+ r+s+i G s +nqrierlW+dvf+ + +vfy +f+a+e++++ldi+ FUN_002247-T1 32 GTNNLSSTVLNLFESAVERDGglWPSRIRVDFGVENTAVCDAMVAVRGEGRGSFIAGSSTRNQRIERLWSDVFRCICHVFYYTFYAMEQTGLLDIE 127 589***************987656************************************************************************ PP rva_4 137 ndihllalhivylpriqkeleefknawnnhklrteknktPlqlfveglleni 188 n ih+++l++v+l+ri+ +l+e++ +n+h+++te+n +P+q++++g++++ FUN_002247-T1 128 NPIHMFTLQYVFLKRINFALSEWMVCFNDHPVQTEQNWSPNQMWLNGMMNSR 179 ************************************************9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (267 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 625 (0.0244666); expected 510.9 (0.02) Passed bias filter: 567 (0.0221961); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 2676.29 // Query: FUN_002248-T1 [L=367] Description: FUN_002248 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-05 23.7 0.9 0.0031 17.6 0.5 2.6 2 HECT HECT-domain (ubiquitin-transferase) Domain annotation for each model (and alignments): >> HECT HECT-domain (ubiquitin-transferase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.3 0.0 0.0029 75 27 70 .. 89 130 .. 54 151 .. 0.77 2 ! 17.6 0.5 1.2e-07 0.0031 219 282 .. 210 337 .. 190 342 .. 0.84 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.0029 xxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 27 fnpesseee....klelfkllGkllGkaiyegllldlpfpraflkkll 70 n +e + ++G++ ++a++++ + + f++ +l+ ++ FUN_002248-T1 89 EN------GlkehLSEDYFFVGQMAAIALLQNGQTPKYFSEDLLQDIF 130 33......13333446799*************9999999998888776 PP == domain 2 score: 17.6 bits; conditional E-value: 1.2e-07 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxx......................................... RF HECT 219 wfweileefseeerrklLkFvTgssrlPlgGfksl..........pkltIqkksg......................................... 263 + e+ + +++L+FvTg s+ P Gf + + + FUN_002248-T1 210 YVREVASGRRVTSLENILEFVTGASEEPTLGFDQQpciefvlatvK--------Eakidrsedgtgnnsthgeskqiitkrlraqkvfklcmlfft 297 44555555555677899****************7767443333333........366677777********************************* PP .....................xxxxxxxxxxxxxxxxxxx RF HECT 264 .....................kdddrLPtahTCfnlLklp 282 + d +P++hTC n+++lp FUN_002248-T1 298 avqvpdkklkvllkkrsrkkrAIADFMPKSHTCSNTMHLP 337 *******************998999**************9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (367 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 565 (0.0221178); expected 510.9 (0.02) Passed bias filter: 519 (0.0203171); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3618.48 // Query: FUN_002249-T1 [L=262] Description: FUN_002249 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.054 13.5 3.1 0.076 13.0 3.1 1.3 1 Mu-like_Pro Mu-like prophage I protein Domain annotation for each model (and alignments): >> Mu-like_Pro Mu-like prophage I protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 3.1 3e-06 0.076 131 228 .. 83 186 .. 70 252 .. 0.80 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 3e-06 Mu-like_Pro 131 eelaalaaaeaqeeeteeeeeeellekllaaLgleeda.teeqilealkalekakkeiaaalglkegaklaeaaaevaa.Lsakk....vDlakyv 220 e+l a aaa+++++++++e++++ lek + l +e++ ++a++ l+k++ + +++l+e++++a+++a++a+ L+++ + ++v FUN_002249-T1 83 ERLRAAAAATSTSTKSKKEKKSKPLEKKPFEFALLRAKsEEDDEEDAVETLKKENIVERGMIELAEDDSEATVRAKIASsLKSQYsllgPNDFEFV 178 6788888888888888888888888888888887665538888999*********99999***************998537777777666656666 PP Mu-like_Pro 221 pveavqal 228 +v + + FUN_002249-T1 179 KVTQKTVS 186 66655544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (262 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2019 (0.079037); expected 510.9 (0.02) Passed bias filter: 662 (0.0259151); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2602.17 // Query: FUN_002250-T1 [L=927] Description: FUN_002250 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-44 146.1 17.3 7.6e-05 23.3 0.0 11.7 11 Ank Ankyrin repeat 2.4e-40 137.5 4.8 1.9e-10 41.6 0.3 5.7 5 Ank_2 Ankyrin repeats (3 copies) 1.7e-36 123.9 7.1 0.00014 22.5 0.1 9.6 10 Ank_4 Ankyrin repeats (many copies) 2.4e-26 92.0 14.4 0.00039 21.2 0.1 8.7 7 Ank_5 Ankyrin repeats (many copies) 7.3e-20 69.2 6.0 0.044 14.8 0.0 10.8 10 Ank_3 Ankyrin repeat 0.0015 18.7 0.1 0.34 11.1 0.0 3.3 4 Ank_KRIT1 KRIT1 ankyrin-repeats domain ------ inclusion threshold ------ 0.04 14.5 0.0 0.089 13.3 0.0 1.6 1 Mab-21 Mab-21 protein nucleotidyltransferase domain Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.0 0.0005 1.8 1 30 [. 43 73 .. 43 76 .. 0.90 2 ! 18.4 0.0 7.4e-07 0.0027 4 30 .. 92 118 .. 92 120 .. 0.88 3 ! 10.8 0.0 0.00021 0.75 15 33 .] 150 168 .. 125 168 .. 0.89 4 ! 18.8 0.3 5.6e-07 0.002 1 32 [. 172 204 .. 172 205 .. 0.91 5 ! 13.4 0.0 3e-05 0.11 3 32 .. 208 237 .. 206 238 .. 0.94 6 ! 23.3 0.0 2.1e-08 7.6e-05 2 32 .. 240 270 .. 239 271 .. 0.91 7 ! 20.3 0.1 1.9e-07 0.00068 3 33 .] 274 310 .. 272 310 .. 0.87 8 ! 7.2 0.1 0.0027 10 2 32 .. 312 346 .. 311 347 .. 0.73 9 ? 4.7 0.0 0.018 64 16 32 .. 414 430 .. 409 431 .. 0.89 10 ! 11.5 0.0 0.00012 0.42 2 32 .. 433 471 .. 432 472 .. 0.88 11 ! 8.3 0.0 0.0012 4.5 1 21 [. 473 493 .. 473 503 .. 0.86 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0005 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvna 30 +G ++L +A+ ++++v+ LLk +Ad+n FUN_002250-T1 43 YGLSALCMAVkAFQSPSLVEKLLKMNADPNF 73 599*******98899********779***95 PP == domain 2 score: 18.4 bits; conditional E-value: 7.4e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvna 30 +PLH+Aa h+ + k LL+ GAd+n FUN_002250-T1 92 SPLHVAAWLRHPGITKVLLDGGADPNT 118 6******999999******547***95 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00021 Ank 15 levvklLLkhGAdvnardk 33 l+v+klL+++GAdv a+d+ FUN_002250-T1 150 LDVMKLLIDNGADVTAVDN 168 67******88******997 PP == domain 4 score: 18.8 bits; conditional E-value: 5.6e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA.dvnard 32 dG + LH+A + gh+ +v++LL+ A dvn+r+ FUN_002250-T1 172 DGTSLLHMATQGGHVLIVNYLLSLRAlDVNCRN 204 7999******************668879**998 PP == domain 5 score: 13.4 bits; conditional E-value: 3e-05 Ank 3 nTPLHlAaraghlevvklL.LkhGAdvnard 32 TPL++A r+++ e+++ L L hGA +n rd FUN_002250-T1 208 ETPLMIALREDRQELLEDLpL-HGAHPNSRD 237 7********************.8******98 PP == domain 6 score: 23.3 bits; conditional E-value: 2.1e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH+A+ + +++ v++L+++ Advn +d FUN_002250-T1 240 GCTALHIAVGRTCVKSVEILIQNSADVNMKD 270 9********778899******878*****99 PP == domain 7 score: 20.3 bits; conditional E-value: 1.9e-07 Ank 3 nTPLHlAaragh......levvklLLkhGAdvnardk 33 +T+LH+A+r ++ ++v+k LL+++Advn+ d+ FUN_002250-T1 274 RTALHVASRLNNsfsksnVKVMKSLLSNNADVNVADN 310 7*******7777777777********879*****997 PP == domain 8 score: 7.2 bits; conditional E-value: 0.0027 Ank 2 GnTPLHlAaragh.....levvklLLkhGAdvnard 32 G+ PLHl + ++ + ++ LL+h Ad+ ++d FUN_002250-T1 312 GRRPLHLTVI-DNkdtldMTALECLLEHDADPSLTD 346 888****993.4424744444466**999***9988 PP == domain 9 score: 4.7 bits; conditional E-value: 0.018 Ank 16 evvklLLkhGAdvnard 32 +v++ L+++G+d+n++d FUN_002250-T1 414 KVIRELVEAGVDINCQD 430 699****99******98 PP == domain 10 score: 11.5 bits; conditional E-value: 0.00012 Ank 2 GnTPLHlAa.ragh.......levvklLLkhGAdvnard 32 G T+LH + r+g+ + + LL++GAd nard FUN_002250-T1 433 GSTCLHHTVgRKGRtsshlkfSDFTRVLLDAGADRNARD 471 99*****99977777778999********88*******9 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0012 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP H+Aa+ + + +++L FUN_002250-T1 473 DGNTPAHIAAEGEDADQLRML 493 8*********87778877777 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 4.1e-08 0.00015 18 88 .. 33 118 .. 22 120 .. 0.77 2 ! 41.6 0.3 5.2e-14 1.9e-10 10 90 .] 150 237 .. 145 237 .. 0.89 3 ! 39.4 0.8 2.7e-13 9.8e-10 12 90 .] 222 309 .. 219 309 .. 0.87 4 ! 17.1 0.1 2.4e-06 0.0087 9 64 .. 291 353 .. 286 376 .. 0.69 5 ! 27.2 0.0 1.7e-09 6.3e-06 11 80 .. 414 494 .. 409 508 .. 0.82 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 4.1e-08 Ank_2 18 egadanlqdkngetaLhlAak.nghleivklLlehgad....vndnn.............grtaLhyAaesghleivklLlekgadina 88 e++++n++++ g +aL +A+k ++ +v+ Ll+ +ad + ++Lh+Aa+ +h i k+Ll+ gad+n+ FUN_002250-T1 33 EKQNPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADpnfeS---YigkflgtrktekpSGSPLHVAAWLRHPGITKVLLDGGADPNT 118 678999999************5567899*99999766633440...24444455555555558******************99****97 PP == domain 2 score: 41.6 bits; conditional E-value: 5.2e-14 Ank_2 10 lelvklLl.egadanlqdk...ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+++klL+ +gad+ +d+ +g++ Lh+A + gh+ iv +Ll+ dvn + + +t+L++A +++++e ++ L +ga++n++d FUN_002250-T1 150 LDVMKLLIdNGADVTAVDNtktDGTSLLHMATQGGHVLIVNYLLSLRaLDVNcrNIHEETPLMIALREDRQELLEDLPLHGAHPNSRD 237 6899*********997777799**********************9654667776888********************989***99987 PP == domain 3 score: 39.4 bits; conditional E-value: 2.7e-13 Ank_2 12 lvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesg......hleivklLlekgadinakd 90 l++ L +ga +n++d g taLh+A+ + ++ v++L++++advn d++ rtaLh+A++ + +++++k Ll+++ad+n+ d FUN_002250-T1 222 LLEDLPlHGAHPNSRDMAGCTALHIAVGRTCVKSVEILIQNSADVNmkDSSCRTALHVASRLNnsfsksNVKVMKSLLSNNADVNVAD 309 56666448999999888***********************99999999999**********964555558***************976 PP == domain 4 score: 17.1 bits; conditional E-value: 2.4e-06 Ank_2 9 nlelvklLl.egadanlqdkngetaLhlAakng..hlei..vklLlehgadvn..dnngrtaL 64 n +++k Ll ++ad+n+ d++g+ +Lhl + + l++ +++Lleh+ad d r +L FUN_002250-T1 291 NVKVMKSLLsNNADVNVADNQGRRPLHLTVIDNkdTLDMtaLECLLEHDADPSltDAIERMPL 353 356888888888999988889999999888876333344556888888554334445555555 PP == domain 5 score: 27.2 bits; conditional E-value: 1.7e-09 Ank_2 11 elvklLl.egadanlqdkngetaLhlAakng.....hlei...vklLlehgadvn..dnngrtaLhyAaesghleivklLl 80 +++++L+ g+d+n+qd +g t Lh+ + + hl++ ++Ll+ gad n d +g+t+ h+Aae + +++L+ FUN_002250-T1 414 KVIRELVeAGVDINCQDIEGSTCLHHTVGRKgrtssHLKFsdfTRVLLDAGADRNarDIDGNTPAHIAAEGEDADQLRMLA 494 48999**9*****************9998543555455435549*****999988999***********988888888887 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.6 5.9e+03 22 49 .. 36 64 .. 31 71 .. 0.75 2 ? 4.1 0.0 0.025 93 1 40 [. 94 133 .. 93 136 .. 0.84 3 ! 22.5 0.1 3.9e-08 0.00014 7 50 .] 147 193 .. 144 193 .. 0.86 4 ! 10.1 0.0 0.00031 1.1 8 42 .. 184 219 .. 184 226 .. 0.86 5 ! 11.5 0.1 0.00012 0.43 4 39 .. 214 249 .. 211 251 .. 0.86 6 ! 20.9 0.0 1.3e-07 0.00048 9 39 .. 252 282 .. 249 288 .. 0.90 7 ! 16.3 0.0 3.5e-06 0.013 7 35 .. 289 317 .. 286 320 .. 0.94 8 ? -0.7 0.0 0.8 2.9e+03 12 34 .. 331 353 .. 328 359 .. 0.82 9 ! 17.6 0.0 1.4e-06 0.0051 11 36 .. 414 439 .. 413 449 .. 0.91 10 ! 21.7 0.0 7.5e-08 0.00027 13 49 .. 457 493 .. 446 494 .. 0.93 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.6 Ank_4 22 dinatdgngetaLhfAa.sngnlevlklL 49 ++n ++ +g +aL +A+ ++ +++ ++ L FUN_002250-T1 36 NPNFVNSYGLSALCMAVkAFQSPSLVEKL 64 66777999999999999666666666666 PP == domain 2 score: 4.1 bits; conditional E-value: 0.025 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasn 40 lh+Aa h + k Ll+ gad+n++ n t+L ++ n FUN_002250-T1 94 LHVAAWLRHPGITKVLLDGGADPNTVaF-NSLTPLLLVLTN 133 6888888999999*************65.589999887765 PP == domain 3 score: 22.5 bits; conditional E-value: 3.9e-08 Ank_4 7 sghlellklLlengadinat.d..gngetaLhfAasngnlevlklLl 50 + l++ klL++ngad+ a+ + +g + Lh+A ++g++ ++ +Ll FUN_002250-T1 147 QAALDVMKLLIDNGADVTAVdNtkTDGTSLLHMATQGGHVLIVNYLL 193 5669************9998434466999**************9997 PP == domain 4 score: 10.1 bits; conditional E-value: 0.00031 Ank_4 8 ghlellklLlen.gadinatdgngetaLhfAasngn 42 gh+ ++ +Ll+ +d+n+++ et+L +A++ + FUN_002250-T1 184 GHVLIVNYLLSLrALDVNCRNIHEETPLMIALREDR 219 79999*****9956*****************98665 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00012 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAas 39 A + ++ell+ L +ga++n +d g taLh+A+ FUN_002250-T1 214 ALREDRQELLEDLPLHGAHPNSRDMAGCTALHIAVG 249 666788899999999*******************95 PP == domain 6 score: 20.9 bits; conditional E-value: 1.3e-07 Ank_4 9 hlellklLlengadinatdgngetaLhfAas 39 +++ ++ L++n ad+n+ d +++taLh A++ FUN_002250-T1 252 CVKSVEILIQNSADVNMKDSSCRTALHVASR 282 7899*************************85 PP == domain 7 score: 16.3 bits; conditional E-value: 3.5e-06 Ank_4 7 sghlellklLlengadinatdgngetaLh 35 ++++++ k+Ll+n ad+n d++g+ +Lh FUN_002250-T1 289 KSNVKVMKSLLSNNADVNVADNQGRRPLH 317 7899************************* PP == domain 8 score: -0.7 bits; conditional E-value: 0.8 Ank_4 12 llklLlengadinatdgngetaL 34 +l+ Lle++ad+ td + +L FUN_002250-T1 331 ALECLLEHDADPSLTDAIERMPL 353 57779*******99998777666 PP == domain 9 score: 17.6 bits; conditional E-value: 1.4e-06 Ank_4 11 ellklLlengadinatdgngetaLhf 36 ++++ L+e g+din++d +g t+Lh+ FUN_002250-T1 414 KVIRELVEAGVDINCQDIEGSTCLHH 439 689**********************7 PP == domain 10 score: 21.7 bits; conditional E-value: 7.5e-08 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklL 49 + Ll+ gad na+d +g+t+ h+Aa +++ + l++L FUN_002250-T1 457 TRVLLDAGADRNARDIDGNTPAHIAAEGEDADQLRML 493 689*****************************99998 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.00088 3.2 8 43 .. 36 72 .. 31 73 .. 0.88 2 ! 18.8 0.0 6.3e-07 0.0023 18 53 .. 92 127 .. 86 129 .. 0.95 3 ? 4.2 0.0 0.024 88 26 47 .. 147 168 .. 145 171 .. 0.88 4 ! 13.3 0.2 3.3e-05 0.12 14 56 .] 171 214 .. 166 214 .. 0.89 5 ! 21.2 0.1 1.1e-07 0.00039 7 56 .] 233 280 .. 228 280 .. 0.84 6 ! 5.8 0.2 0.0074 27 1 54 [. 298 354 .. 298 355 .. 0.72 7 ! 20.1 0.1 2.4e-07 0.00088 1 56 [] 419 481 .. 419 481 .. 0.89 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00088 Ank_5 8 dlnrldgegytpLhvAak.ygaleivrlLlangvdln 43 ++n + +g +L++A+k ++ +v++Ll+ ++d+n FUN_002250-T1 36 NPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADPN 72 677779999*********************8888876 PP == domain 2 score: 18.8 bits; conditional E-value: 6.3e-07 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 pLhvAa+ +++ i ++Ll+ g+d+n+ ++ ltpl FUN_002250-T1 92 SPLHVAAWLRHPGITKVLLDGGADPNTVAFNSLTPL 127 79********************************98 PP == domain 3 score: 4.2 bits; conditional E-value: 0.024 Ank_5 26 ygaleivrlLlangvdlnlkde 47 + al++++lL++ng+d+++ d+ FUN_002250-T1 147 QAALDVMKLLIDNGADVTAVDN 168 6799**************9997 PP == domain 4 score: 13.3 bits; conditional E-value: 3.3e-05 Ank_5 14 gegytpLhvAakygaleivrlLl.angvdlnlkdeegltpldlA 56 ++g+ Lh+A +g+ iv++Ll + d+n+++ + +tpl +A FUN_002250-T1 171 TDGTSLLHMATQGGHVLIVNYLLsLRALDVNCRNIHEETPLMIA 214 457799**********************************9776 PP == domain 5 score: 21.2 bits; conditional E-value: 1.1e-07 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + + g+ t+Lh+A+ + + v++L+ n +d+n+kd+++ t+l++A FUN_002250-T1 233 PNSRDMAGC--TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVA 280 344444445..************************************998 PP == domain 6 score: 5.8 bits; conditional E-value: 0.0074 Ank_5 1 LlengpadlnrldgegytpLhvAakyga..leivrlLl..angvdlnlkdeegltpld 54 Ll n ad+n d+ g pLh+ + + l++ l + ++++d+ l+d+ +pl FUN_002250-T1 298 LLSNN-ADVNVADNQGRRPLHLTVIDNKdtLDMTALECllEHDADPSLTDAIERMPLS 354 67776.99999999999****9888665114444444445999999999988777775 PP == domain 7 score: 20.1 bits; conditional E-value: 2.4e-07 Ank_5 1 LlengpadlnrldgegytpLhvAak.yga.......leivrlLlangvdlnlkdeegltpldlA 56 L+e+g +d+n++d eg t+Lh+ + +g+ +++ r+Ll+ g+d n++d +g+tp ++A FUN_002250-T1 419 LVEAG-VDINCQDIEGSTCLHHTVGrKGRtsshlkfSDFTRVLLDAGADRNARDIDGNTPAHIA 481 89999.88888888999********999955555556899**********************98 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.19 6.9e+02 8 30 .. 50 72 .. 43 73 .. 0.72 2 ! 9.2 0.0 0.00082 3 4 30 .. 92 117 .. 90 118 .. 0.95 3 ? 4.4 0.0 0.031 1.1e+02 13 30 .. 148 164 .. 144 165 .. 0.84 4 ! 8.3 0.1 0.0017 6.2 4 30 .. 175 201 .. 172 202 .. 0.87 5 ? 2.6 0.0 0.12 4.5e+02 3 21 .. 208 226 .. 206 235 .. 0.76 6 ! 14.8 0.0 1.2e-05 0.044 2 31 .] 240 268 .. 239 268 .. 0.96 7 ! 10.0 0.0 0.00044 1.6 3 31 .] 274 307 .. 274 307 .. 0.94 8 ? 3.3 0.0 0.069 2.5e+02 2 29 .. 312 342 .. 311 344 .. 0.73 9 ? 1.1 0.0 0.38 1.4e+03 17 31 .] 415 428 .. 410 428 .. 0.89 10 ? 3.4 0.0 0.064 2.3e+02 1 14 [. 473 486 .. 473 497 .. 0.81 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.19 Ank_3 8 lAarngrle.ivklLleklgadin 30 +A++ + + +v+ Ll+ ++ad+n FUN_002250-T1 50 MAVKAFQSPsLVEKLLK-MNADPN 72 55555555559******.****99 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00082 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa ++ i k+Ll+ gad+n FUN_002250-T1 92 SPLHVAAWLRHPGITKVLLD-GGADPN 117 8*******************.*****9 PP == domain 3 score: 4.4 bits; conditional E-value: 0.031 Ank_3 13 grleivklLleklgadin 30 + l+++klL++ +gad+ FUN_002250-T1 148 AALDVMKLLID-NGADVT 164 6789*******.****85 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0017 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 ++Lh+A g++ iv +Ll + d+n FUN_002250-T1 175 SLLHMATQGGHVLIVNYLLSLRALDVN 201 89*****************98777777 PP == domain 5 score: 2.6 bits; conditional E-value: 0.12 Ank_3 3 ntpLhlAarngrleivklL 21 +tpL++A r +r e+++ L FUN_002250-T1 208 ETPLMIALREDRQELLEDL 226 8********9987777655 PP == domain 6 score: 14.8 bits; conditional E-value: 1.2e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+t+Lh+A+ +++ v+ L++ + ad+n+ FUN_002250-T1 240 GCTALHIAVGRTCVKSVEILIQ-NSADVNM 268 89************99******.*****95 PP == domain 7 score: 10.0 bits; conditional E-value: 0.00044 Ank_3 3 ntpLhlAarngrl......eivklLleklgadina 31 +t+Lh+A r ++ +++k Ll ++ad+n+ FUN_002250-T1 274 RTALHVASRLNNSfsksnvKVMKSLLS-NNADVNV 307 79**************99889******.*****95 PP == domain 8 score: 3.3 bits; conditional E-value: 0.069 Ank_3 2 gntpLh.lAarngrl...eivklLleklgadi 29 g+ pLh +++ n + +++++Lle + ad+ FUN_002250-T1 312 GRRPLHlTVIDNKDTldmTALECLLE-HDADP 342 88999955555555564445******.99998 PP == domain 9 score: 1.1 bits; conditional E-value: 0.38 Ank_3 17 ivklLleklgadina 31 +++ L+e g+din+ FUN_002250-T1 415 VIRELVE-AGVDINC 428 79*****.9****96 PP == domain 10 score: 3.4 bits; conditional E-value: 0.064 Ank_3 1 dgntpLhlAarngr 14 dgntp h+Aa+ + FUN_002250-T1 473 DGNTPAHIAAEGED 486 79*******98665 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.048 1.7e+02 42 78 .. 85 121 .. 60 133 .. 0.72 2 ! 11.1 0.0 9.3e-05 0.34 42 125 .. 169 247 .. 159 257 .. 0.69 3 ? 0.6 0.0 0.16 5.9e+02 87 142 .. 242 297 .. 234 303 .. 0.77 4 ? -3.6 0.0 3.1 1.1e+04 109 128 .. 464 484 .. 457 493 .. 0.63 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.048 Ank_KRIT1 42 ekvddpes.lvaAakgGheevlqlLlalGkadpdPepv 78 ++ + + s l+ Aa+ h ++++Ll+ G+adp+ + FUN_002250-T1 85 KTEKPSGSpLHVAAWLRHPGITKVLLD-GGADPNTVAF 121 4444343459****************8.6688885444 PP == domain 2 score: 11.1 bits; conditional E-value: 9.3e-05 Ank_KRIT1 42 ekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvikllldqeefdptrrlkgetyleia 125 +k+d + l++A++gGh ++++Ll l d + + +++ +tPl+ a ++ ++++ l + +r + g t l ia FUN_002250-T1 169 TKTDGTSLLHMATQGGHVLIVNYLLSLRALDVNCRNIHE-----ETPLMIALREDRQELLEDLPLHGAHPNSRDMAGCTALHIA 247 34444555899*****************99999665554.....6888888877777777655444444444446666666665 PP == domain 3 score: 0.6 bits; conditional E-value: 0.16 Ank_KRIT1 87 tPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgenweeeeklLke 142 t l a+Gr +k +++l++++ ++ +t l +a + +++ + + k++k+ FUN_002250-T1 242 TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVASRLNNSFSKSNVKVMKS 297 5667799*********9997665444555889999999998888888888888775 PP == domain 4 score: -3.6 bits; conditional E-value: 3.1 Ank_KRIT1 109 efdptrr.lkgetyleiarer 128 + d++ r + g+t++ ia+e FUN_002250-T1 464 GADRNARdIDGNTPAHIAAEG 484 345554448888888888764 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 2.4e-05 0.089 3 138 .. 749 891 .. 747 911 .. 0.67 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.4e-05 Mab-21 3 enlkvlsPdeFdlvlkLklpeneeiivkedpggpgyvelkltrsg..esndnsrkellsqwleeaegylsaaKvlsrfqslvekalkklekeievn 96 e++k +PdeFd++ +L+ + + +++ y+ l +++ s d++ ke ++++l + ++ ls +K++ f l +a l+++++ + FUN_002250-T1 749 EETKLWKPDEFDFMMELTQL--------KGHSRLEYAGLSRSSNTtvISLDDEMKEMWREFL-K-DDCLSLEKLRDYFVLLTWRAGFSLQRQKY-K 833 789999***********922........3333355555555552235555679999999999.6.899**999999999999999888766555.3 PP Mab-21 97 detlklsykrk.......gpavt.....vaietseeq..............ysVdlvpaielkasWpk 138 + +ls ++ p v+ v ++Vdl++++++++ Wp FUN_002250-T1 834 NLSFNLS--QQsggtgssHPLVRmssvgV-------LlhvqwhgydytsldIDVDLTLSVPFSD-WPV 891 3333333..33568866633333323222.......122333346688899*************.996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (927 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 651 (0.0254844); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 46 (0.00180074); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.42u 0.39s 00:00:00.81 Elapsed: 00:00:00.42 # Mc/sec: 8917.93 // Query: FUN_002251-T1 [L=178] Description: FUN_002251 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 406 (0.0158935); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1752.36 // Query: FUN_002252-T1 [L=124] Description: FUN_002252 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-18 65.9 0.4 5.8e-18 65.6 0.4 1.2 1 Histone Core histone H2A/H2B/H3/H4 domain 2e-08 34.5 0.0 2.5e-08 34.1 0.0 1.2 1 Histone_ABTB Histone domain in ABTB family protein 0.0034 18.1 0.0 0.0069 17.1 0.0 1.5 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.051 14.1 0.3 0.06 13.8 0.3 1.2 1 YscO-like YscO-like protein 0.25 12.4 0.0 0.48 11.5 0.0 1.4 1 TFIID_20kDa Transcription initiation factor TFIID subunit Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.6 0.4 1.1e-21 5.8e-18 7 88 .] 22 99 .. 16 99 .. 0.94 Alignments for each domain: == domain 1 score: 65.6 bits; conditional E-value: 1.1e-21 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ +++++++++ ++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_002252-T1 22 AETAKRRRGKRKESYAIYKYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.0 4.9e-12 2.5e-08 23 91 .. 53 123 .. 37 124 .] 0.86 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 4.9e-12 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_002252-T1 53 ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 123 7888888899999999************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.3e-06 0.0069 10 65 .] 42 97 .. 41 97 .. 0.95 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 CBFD_NFYB_HMF 10 rImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_002252-T1 42 KVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 97 899***88888.*****************************************9996 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.3 1.2e-05 0.06 38 113 .. 25 99 .. 6 119 .. 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.2e-05 YscO-like 38 lakleaerdkvlkhkkaKlqqlrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 ++++ +r + + K + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_002252-T1 25 AKRRRGKRKESYAIY--KYKVLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 333333344444444..44445542569******************************************9988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.4e-05 0.48 8 60 .. 43 95 .. 41 99 .. 0.93 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.4e-05 TFIID_20kDa 8 LvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_002252-T1 43 VLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 95 5899***********************************************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 480 (0.0187904); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1240.30 // Query: FUN_002253-T1 [L=61] Description: FUN_002253 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0005 20.6 0.0 0.00053 20.6 0.0 1.1 1 CENP-T_C Centromere kinetochore component CENP-T histon 0.0011 19.8 0.1 0.0012 19.6 0.1 1.2 1 Histone Core histone H2A/H2B/H3/H4 domain 0.0044 17.6 0.0 0.0052 17.4 0.0 1.2 1 TAF TATA box binding protein associated factor (TA 0.0058 17.4 0.1 0.0078 16.9 0.1 1.2 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.011 16.4 0.0 0.011 16.4 0.0 1.0 1 Csa5_I-A Type-I-A Cascade subunit Csa5 0.018 15.9 0.1 0.023 15.6 0.1 1.3 1 CENP-S CENP-S protein Domain annotation for each model (and alignments): >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 1.2e-07 0.00053 43 70 .. 20 47 .. 8 56 .. 0.89 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 1.2e-07 CENP-T_C 43 sewffeqvseDLeayakHAgRKtidesD 70 ++ f+e v D +y++HA+RKt+ D FUN_002253-T1 20 LKVFLENVIRDAVTYTEHAKRKTVTAMD 47 678*********************9888 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.1 2.9e-07 0.0012 54 81 .. 20 47 .. 17 61 .] 0.92 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 2.9e-07 Histone 54 vedllvelfeeAnllakhaKRvTltpkD 81 ++ +l+ + ++A +++haKR+T+t+ D FUN_002253-T1 20 LKVFLENVIRDAVTYTEHAKRKTVTAMD 47 6789********************9987 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 1.2e-06 0.0052 37 60 .. 24 47 .. 11 52 .. 0.91 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 1.2e-06 TAF 37 lkeivqeaakfmrhskRrkLtvaD 60 l +++++a+ +++h+kR++ t+ D FUN_002253-T1 24 LENVIRDAVTYTEHAKRKTVTAMD 47 6789******************99 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 1.8e-06 0.0078 33 60 .. 20 47 .. 16 49 .. 0.91 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1.8e-06 CBFD_NFYB_HMF 33 veefieevaseAaeickkekrKTikaeh 60 + f+e v + A+ +++++krKT++a + FUN_002253-T1 20 LKVFLENVIRDAVTYTEHAKRKTVTAMD 47 5679********************9866 PP >> Csa5_I-A Type-I-A Cascade subunit Csa5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.4 0.0 2.7e-06 0.011 22 74 .. 3 55 .. 1 59 [. 0.88 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 2.7e-06 Csa5_I-A 22 rrfgyidpliysldpkqikdvlsealreyvsylasaskrsvvlkddkkeqved 74 r g+i liy +k l + +r+ v+y+ a +++v+ d++ e e+ FUN_002253-T1 3 RGVGHISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDKHSELSEK 55 6789*************************************999877665555 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.1 5.4e-06 0.023 42 65 .. 24 47 .. 2 49 .. 0.85 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 5.4e-06 CENP-S 42 lenlakDLeaFAkHAkRstittdD 65 len+ +D ++ +HAkR+t+t+ D FUN_002253-T1 24 LENVIRDAVTYTEHAKRKTVTAMD 47 78999***************9987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (61 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 830 (0.0324917); expected 510.9 (0.02) Passed bias filter: 523 (0.0204737); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 631.14 // Query: FUN_002254-T1 [L=209] Description: FUN_002254 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-08 32.8 0.3 2e-07 31.5 0.1 1.8 2 CENP-T_C Centromere kinetochore component CENP-T histon 0.00043 21.1 0.2 0.0053 17.6 0.0 2.2 2 CENP-S CENP-S protein 0.00048 20.7 0.1 0.021 15.4 0.0 2.1 2 TFIID-31kDa Transcription initiation factor IID, 31kD subu 0.00091 19.8 0.0 0.0016 19.1 0.0 1.5 1 TAF TATA box binding protein associated factor (TA 0.0035 18.2 0.2 0.006 17.4 0.2 1.5 1 Histone Core histone H2A/H2B/H3/H4 domain 0.0041 17.9 0.1 0.0093 16.7 0.1 1.7 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.058 13.9 0.2 0.17 12.4 0.1 1.8 2 Bromo_TP Bromodomain associated Domain annotation for each model (and alignments): >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 1.4 5.2e+03 35 64 .. 56 85 .. 36 88 .. 0.63 2 ! 31.5 0.1 5.6e-11 2e-07 28 80 .. 150 202 .. 123 206 .. 0.81 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 1.4 CENP-T_C 35 alealeqasewffeqvseDLeayakHAgRK 64 l+ +e+ + ++ + Le + + A RK FUN_002254-T1 56 ILQFVESLEYHSHKKSHKSLESFLELAARK 85 455555555555555566677777777776 PP == domain 2 score: 31.5 bits; conditional E-value: 5.6e-11 CENP-T_C 28 kaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 +++s e +++ f+e v D +y++HA RKt+ Dv+ lkRq++ FUN_002254-T1 150 VKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAERKTVTAMDVVYALKRQGR 202 456666667777778899*********************************75 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.18 6.5e+02 19 59 .. 45 85 .. 32 91 .. 0.79 2 ! 17.6 0.0 1.5e-06 0.0053 42 73 .. 169 200 .. 140 203 .. 0.89 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.18 CENP-S 19 aleekvevtpqfiaaltelvykqlenlakDLeaFAkHAkRs 59 ++ +++ p++++ + l y+ ++ k Le+F + A R+ FUN_002254-T1 45 DHKLQLQWDPKILQFVESLEYHSHKKSHKSLESFLELAARK 85 45677888899999999999999999999999998888876 PP == domain 2 score: 17.6 bits; conditional E-value: 1.5e-06 CENP-S 42 lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 len+ +D ++ +HA+R+t+t+ Dv+ ++r+ FUN_002254-T1 169 LENVIRDAVTYTEHAERKTVTAMDVVYALKRQ 200 789999*******************9998885 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.03 1.1e+02 77 109 .. 71 105 .. 38 109 .. 0.80 2 ! 15.4 0.0 5.9e-06 0.021 38 70 .. 168 200 .. 140 205 .. 0.85 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.03 TFIID-31kDa 77 epppkelLlelArerNk..kpLpkvkeklglrLPp 109 ++ + e lelA+++N+ +pLp ++++ LP FUN_002254-T1 71 SHKSLESFLELAARKNTpvTPLPLIDNDTVQILPA 105 445668899*******75589**999987666665 PP == domain 2 score: 15.4 bits; conditional E-value: 5.9e-06 TFIID-31kDa 38 YttevledAkvysehakkkkidlddvrlAiqsr 70 + +v++dA +y eha++k++++ dv A++ + FUN_002254-T1 168 FLENVIRDAVTYTEHAERKTVTAMDVVYALKRQ 200 6789***********************999765 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 4.3e-07 0.0016 34 66 .] 166 198 .. 133 198 .. 0.78 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 4.3e-07 TAF 34 eyrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 + l +++++a+ +++h+ R++ t+ Dv +AL+ FUN_002254-T1 166 KVFLENVIRDAVTYTEHAERKTVTAMDVVYALK 198 555889*************************97 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.2 1.6e-06 0.006 54 87 .. 165 198 .. 124 199 .. 0.91 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 1.6e-06 Histone 54 vedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 ++ +l+ + ++A +++ha R+T+t+ D+ A++ FUN_002254-T1 165 LKVFLENVIRDAVTYTEHAERKTVTAMDVVYALK 198 788**************************99986 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.1 2.5e-06 0.0093 32 65 .] 164 197 .. 138 197 .. 0.84 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 2.5e-06 CBFD_NFYB_HMF 32 cveefieevaseAaeickkekrKTikaehiklAv 65 ++ f+e v + A+ ++++++rKT++a ++ A+ FUN_002254-T1 164 VLKVFLENVIRDAVTYTEHAERKTVTAMDVVYAL 197 5778*************************98876 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 2.1 7.6e+03 47 56 .. 75 84 .. 69 87 .. 0.69 2 ? 12.4 0.1 4.6e-05 0.17 34 70 .. 163 199 .. 158 205 .. 0.89 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 2.1 Bromo_TP 47 aksfaehagR 56 +sf+e+a+R FUN_002254-T1 75 LESFLELAAR 84 4567777777 PP == domain 2 score: 12.4 bits; conditional E-value: 4.6e-05 Bromo_TP 34 eiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 ++++ +++++ ++a + eha R ++t Dvv +L++ FUN_002254-T1 163 GVLKVFLENVIRDAVTYTEHAERKTVTAMDVVYALKR 199 56778999999************************98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (209 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 830 (0.0324917); expected 510.9 (0.02) Passed bias filter: 707 (0.0276766); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2083.38 // Query: FUN_002255-T1 [L=90] Description: FUN_002255 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (90 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 325 (0.0127226); expected 510.9 (0.02) Passed bias filter: 304 (0.0119006); expected 510.9 (0.02) Passed Vit filter: 13 (0.000508906); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.38s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 917.54 // Query: FUN_002256-T1 [L=129] Description: FUN_002256 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 912 (0.0357017); expected 510.9 (0.02) Passed bias filter: 604 (0.0236445); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 1318.97 // Query: FUN_002257-T1 [L=144] Description: FUN_002257 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0034 17.7 0.5 0.0049 17.2 0.5 1.4 1 TRIM_CC TRIM protein coiled-coil region 0.0037 17.8 1.7 0.0054 17.3 1.7 1.2 1 CENP-F_leu_zip Leucine-rich repeats of kinetochore protein C ------ inclusion threshold ------ 0.031 14.4 0.6 0.042 14.0 0.6 1.2 1 Plectin_PPL Periplakin-like, plectin repeat 0.07 13.7 0.0 0.16 12.5 0.0 1.6 1 WHD_F93 F-93, winged-helix domain 0.073 14.0 0.1 0.11 13.4 0.1 1.3 1 DUF5905 Family of unknown function (DUF5905) 0.12 12.9 2.1 0.23 12.0 2.1 1.4 1 CCDC138_cc Coiled-coil-domain-containing protein 138, co Domain annotation for each model (and alignments): >> TRIM_CC TRIM protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.5 1.2e-06 0.0049 63 98 .. 2 38 .. 1 71 [. 0.91 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.2e-06 TRIM_CC 63 eglleeLeqeiaeLkkrdaeleq.LsqteDhihFLqe 98 ++ ++Le++++e + +++le+ L + +Dhi+FL+ FUN_002257-T1 2 QKTTDQLEKDLSEVSRMKENLESeLNKAKDHIQFLKG 38 56789****************976***********96 PP >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 1.7 1.3e-06 0.0054 64 103 .. 1 40 [. 1 47 [. 0.90 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 1.3e-06 CENP-F_leu_zip 64 laeelrqleldLvtlrsekeeLtkeLqkkqervseLesln 103 +++++ qle dL+++++ ke+L++eL+k ++ ++ L+ + FUN_002257-T1 1 MQKTTDQLEKDLSEVSRMKENLESELNKAKDHIQFLKGKK 40 78999****************************9998765 PP >> Plectin_PPL Periplakin-like, plectin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.6 9.9e-06 0.042 7 57 .. 5 55 .. 1 73 [. 0.82 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 9.9e-06 Plectin_PPL 7 lerlrkeleeerrkrsklekEieqlqkklatlesekkkveeklvtkevvkl 57 ++l+k l e +r +++le+E+++++ ++ l+ +k +++ ++ ++vk FUN_002257-T1 5 TDQLEKDLSEVSRMKENLESELNKAKDHIQFLKGKKDYITKVSLIFQIVKT 55 567899999999999999999999999999999999888887777777776 PP >> WHD_F93 F-93, winged-helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 3.8e-05 0.16 26 55 .. 95 124 .. 79 128 .. 0.81 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 3.8e-05 WHD_F93 26 elaqstfydvkeeLiqeGlvaeReeegkkr 55 +a++ f ++++ + ++G+++ R++ +++r FUN_002257-T1 95 TFAPALFTQILKSILNNGMIKDRQDTQRRR 124 67999*******************988877 PP >> DUF5905 Family of unknown function (DUF5905) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.1 2.7e-05 0.11 10 55 .. 14 57 .. 6 75 .. 0.74 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 2.7e-05 DUF5905 10 efsdLleGkireekvsllllayllGketeeYiekleraldalekvr 55 e+s ++e +e + + ++++l Gk ++Yi+k++ +++ ++ r FUN_002257-T1 14 EVSRMKENLESELNKAKDHIQFLKGK--KDYITKVSLIFQIVKTSR 57 455555555557788889********..9**********9998443 PP >> CCDC138_cc Coiled-coil-domain-containing protein 138, coiled-coil # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 2.1 5.4e-05 0.23 14 56 .. 2 44 .. 1 46 [. 0.92 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.4e-05 CCDC138_cc 14 kelNDslkkqlnevseqnkkLesQskkvqaRLeNLqRKqefse 56 ++ D+l k+l+evs ++ Les +k + ++ L+ K+++ + FUN_002257-T1 2 QKTTDQLEKDLSEVSRMKENLESELNKAKDHIQFLKGKKDYIT 44 6678********************************9999976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1643 (0.0643179); expected 510.9 (0.02) Passed bias filter: 1074 (0.0420435); expected 510.9 (0.02) Passed Vit filter: 149 (0.00583284); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1468.38 // Query: FUN_002258-T1 [L=129] Description: FUN_002258 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 11.1 0.0 0.23 11.1 0.0 1.1 1 DUF1464 Protein of unknown function (DUF1464) Domain annotation for each model (and alignments): >> DUF1464 Protein of unknown function (DUF1464) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 9e-06 0.23 7 67 .. 7 66 .. 5 109 .. 0.81 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 9e-06 DUF1464 7 ksydvvavdelgkvvlekeiptdevekdpsvlvkaieearadivalpSGyGlPlkkisela 67 + ++++ +d+ +v k++pt++++ ++ ++ + + +++i a+p +Pl++ +++ FUN_002258-T1 7 NCFAILLIDDYHNVH-AKKVPTKLITSTATHMASCLLDIHPTIPAVPHPQQTPLHRPVKIT 66 5799******77765.678*****************************9999999987776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1079 (0.0422392); expected 510.9 (0.02) Passed bias filter: 880 (0.034449); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1302.86 // Query: FUN_002262-T1 [L=189] Description: FUN_002262 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.029 13.2 0.2 4.1 6.1 0.1 2.1 2 Gp58 gp58-like protein 0.19 12.4 0.8 36 5.1 0.2 2.8 2 DUF4825 Domain of unknown function (DUF4825) 0.45 11.4 32.1 5.4 8.0 1.3 5.1 5 DUF2554 Protein of unknown function (DUF2554) 0.91 10.3 15.0 2.3 9.0 1.3 3.2 3 clamp_Gag1-like Gag1-like, clamp domain 1 9.8 9.9 16 5.9 0.1 4.6 4 Herpes_UL52 Herpesviridae UL52/UL70 DNA primase Domain annotation for each model (and alignments): >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.0016 8.2 221 256 .. 18 53 .. 6 64 .. 0.82 2 ? 6.1 0.1 0.0008 4.1 216 283 .. 93 159 .. 72 174 .. 0.80 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.0016 Gp58 221 tteayeskLddlraeftrsnqGmrveleskisGlqs 256 + +e+k d+lr ++ + + G+rv+ e k G++ FUN_002262-T1 18 VRDDHEKKYDGLRVHHEKKSDGVRVDHEKKSHGVRV 53 567789999999999999999999999999888765 PP == domain 2 score: 6.1 bits; conditional E-value: 0.0008 Gp58 216 ttssGtteayeskLddlraeftrsnqGmrveleskisGlqstqqatakqisqeisnregavsrvqqdl 283 + s+G t e+k d +r ++ + + G+rv+ e k G++ + ++ ++ e ++r++ v+ v+ + FUN_002262-T1 93 KKSDGLTVHQEKKSDRVRVDHEKKSHGVRVDHEEKSEGVRVYHEKKSEGVKVEHEKRSDGVT-VHHEK 159 6788999999999999*******************999999988888888888877777664.44444 PP >> DUF4825 Domain of unknown function (DUF4825) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.009 46 22 61 .. 29 68 .. 25 82 .. 0.84 2 ? 5.1 0.2 0.0071 36 22 61 .. 98 137 .. 95 174 .. 0.82 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.009 DUF4825 22 lplpekvkydsieLqtekepYgitvnyktkeaakeakklk 61 l + ++k d++ ek+ +g+ v+ ++k++ + ++ k FUN_002262-T1 29 LRVHHEKKSDGVRVDHEKKSHGVRVDHEEKSEGVRVYHEK 68 6667778889******************999988777655 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0071 DUF4825 22 lplpekvkydsieLqtekepYgitvnyktkeaakeakklk 61 l + +++k d + ek+ +g+ v+ ++k++ + ++ k FUN_002262-T1 98 LTVHQEKKSDRVRVDHEKKSHGVRVDHEEKSEGVRVYHEK 137 5666777889999999999999999999998887776655 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 1.3 0.0011 5.4 36 64 .. 6 34 .. 2 39 .. 0.87 2 ? 7.1 0.9 0.002 10 37 64 .. 40 67 .. 34 74 .. 0.85 3 ? 4.5 0.9 0.013 66 38 66 .. 77 105 .. 70 111 .. 0.84 4 ? 6.7 1.5 0.0027 14 39 65 .. 111 137 .. 104 151 .. 0.76 5 ? 5.3 2.1 0.0075 38 38 64 .. 154 180 .. 141 188 .. 0.83 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0011 DUF2554 36 dhqlrheadsdelravaeesaeGlrehfy 64 + ++ he sd +r e+ +Glr h+ FUN_002262-T1 6 GVRVHHEKRSDWVRDDHEKKYDGLRVHHE 34 56789**********************97 PP == domain 2 score: 7.1 bits; conditional E-value: 0.002 DUF2554 37 hqlrheadsdelravaeesaeGlrehfy 64 ++ he s +r ee +eG+r ++ FUN_002262-T1 40 VRVDHEKKSHGVRVDHEEKSEGVRVYHE 67 5678********************9886 PP == domain 3 score: 4.5 bits; conditional E-value: 0.013 DUF2554 38 qlrheadsdelravaeesaeGlrehfywq 66 ++ he sd +r e+ ++Gl h + FUN_002262-T1 77 KVHHEKRSDWVRDDHEKKSDGLTVHQEKK 105 689*******************9997644 PP == domain 4 score: 6.7 bits; conditional E-value: 0.0027 DUF2554 39 lrheadsdelravaeesaeGlrehfyw 65 + he s +r ee +eG+r ++ FUN_002262-T1 111 VDHEKKSHGVRVDHEEKSEGVRVYHEK 137 568999999999999999999987753 PP == domain 5 score: 5.3 bits; conditional E-value: 0.0075 DUF2554 38 qlrheadsdelravaeesaeGlrehfy 64 + he sd +r e ++ lr h++ FUN_002262-T1 154 TVHHEKKSDWVRLQHERKSDRLRVHHK 180 578999*****************9996 PP >> clamp_Gag1-like Gag1-like, clamp domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.2 0.003 15 39 63 .. 4 28 .. 1 46 [. 0.75 2 ? 9.0 1.3 0.00045 2.3 21 65 .. 55 99 .. 38 120 .. 0.68 3 ? 2.5 3.0 0.046 2.4e+02 23 65 .. 134 176 .. 108 188 .. 0.68 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.003 clamp_Gag1-like 39 NeGlalweerRdaWtgakkvrkkek 63 +G+++ +e+R+ W+ +++++k+ FUN_002262-T1 4 SDGVRVHHEKRSDWVRDDHEKKYDG 28 589************9999888754 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00045 clamp_Gag1-like 21 lderkrkrrraleeemkwNeGlalweerRdaWtgakkvrkkekke 65 +e+++ r +e++ +G+++ +e+R+ W+ +++++k+ + FUN_002262-T1 55 HEEKSEGVRVYHEKKSDGSDGVKVHHEKRSDWVRDDHEKKSDGLT 99 3366777777788889999**************998887764333 PP == domain 3 score: 2.5 bits; conditional E-value: 0.046 clamp_Gag1-like 23 erkrkrrraleeemkwNeGlalweerRdaWtgakkvrkkekke 65 +++k++ e++k +G+++ +e+ + W+ +++rk+ + + FUN_002262-T1 134 YHEKKSEGVKVEHEKRSDGVTVHHEKKSDWVRLQHERKSDRLR 176 344444444556778889*************988888775443 PP >> Herpes_UL52 Herpesviridae UL52/UL70 DNA primase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.2 0.081 4.2e+02 24 37 .. 29 42 .. 7 50 .. 0.84 2 ? 5.9 0.1 0.0032 16 25 48 .. 52 76 .. 41 80 .. 0.84 3 ? 5.3 0.3 0.0049 25 24 45 .. 120 141 .. 94 145 .. 0.76 4 ? -0.9 0.1 0.42 2.1e+03 27 37 .. 145 155 .. 142 174 .. 0.55 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.081 Herpes_UL52 24 lnikhrhksnnvrv 37 l++ h+ ks++vrv FUN_002262-T1 29 LRVHHEKKSDGVRV 42 79999*****9987 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0032 Herpes_UL52 25 nikhrhksnnvrvfldlrvdkes.l 48 ++ h+ ks++vrv+ + ++d+++ + FUN_002262-T1 52 RVDHEEKSEGVRVYHEKKSDGSDgV 76 889***********99999987655 PP == domain 3 score: 5.3 bits; conditional E-value: 0.0049 Herpes_UL52 24 lnikhrhksnnvrvfldlrvdk 45 +++ h+ ks++vrv+ + ++++ FUN_002262-T1 120 VRVDHEEKSEGVRVYHEKKSEG 141 5889999999999998877766 PP == domain 4 score: -0.9 bits; conditional E-value: 0.42 Herpes_UL52 27 khrhksnnvrv 37 +h+ +s++v v FUN_002262-T1 145 EHEKRSDGVTV 155 56666666433 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (189 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1093 (0.0427872); expected 510.9 (0.02) Passed bias filter: 282 (0.0110393); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1883.11 // Query: FUN_002263-T1 [L=205] Description: FUN_002263 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.026 13.4 0.7 0.78 8.5 0.1 2.6 3 Gp58 gp58-like protein 0.027 14.5 6.9 2 8.4 0.5 3.2 3 DUF1444 Protein of unknown function (DUF1444) 1 10.3 16.7 3.7 8.5 2.5 4.3 5 DUF2554 Protein of unknown function (DUF2554) 3.3 8.2 5.7 1.1e+02 3.3 0.1 4.2 4 ComGE Competence system putative prepilin ComGE 5 7.6 18.0 63 4.1 0.0 7.4 10 Beta-APP Beta-amyloid peptide (beta-APP) Domain annotation for each model (and alignments): >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.014 70 228 256 .. 25 53 .. 13 81 .. 0.64 2 ? -0.1 0.0 0.059 3e+02 526 550 .. 76 100 .. 63 119 .. 0.77 3 ? 8.5 0.1 0.00015 0.78 217 260 .. 121 164 .. 79 190 .. 0.69 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.014 Gp58 228 kLddlraeftrsnqGmrveleskisGlqs 256 k d lra++ + G+rv e k G++ FUN_002263-T1 25 KSDRLRADHEKMRDGVRVHHERKSNGVRV 53 55566666666666666666666666543 PP == domain 2 score: -0.1 bits; conditional E-value: 0.059 Gp58 526 sssdgidsaesgrfaGirifryasg 550 +sdg+ ++ ++ G+r+ + +++ FUN_002263-T1 76 RKSDGVRVHDMKKSNGVRVLHEKKS 100 4799999999999999999887765 PP == domain 3 score: 8.5 bits; conditional E-value: 0.00015 Gp58 217 tssGtteayeskLddlraeftrsnqGmrveleskisGlqstqqa 260 s G +e+k d++r + r + Gmrv+ e k G++ + FUN_002263-T1 121 KSGGMRVHHEKKRDGVRVYYERKSDGMRVNHEKKSEGVKVDHEK 164 45555566788888999999999999999999888887755444 PP >> DUF1444 Protein of unknown function (DUF1444) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.11 5.8e+02 17 43 .. 16 42 .. 3 46 .. 0.75 2 ? 8.2 0.4 0.00044 2.3 5 74 .. 35 106 .. 31 120 .. 0.74 3 ? 8.4 0.5 0.00039 2 11 47 .. 128 164 .. 119 199 .. 0.79 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.11 DUF1444 17 eevtlkfdreedtlriedkktkkgvti 43 + v++ +++++d+lr ++k++ gv + FUN_002263-T1 16 DWVRVDHKKKSDRLRADHEKMRDGVRV 42 445778889999999999999999877 PP == domain 2 score: 8.2 bits; conditional E-value: 0.00044 DUF1444 5 klkkkle..eklkeeevtlkfdreedtlriedkktkkgvtiklkeliakyeekkekaidevveyveealkal 74 k+++ ++ ++ k++ v++ ++r++d l +e++k+ +g ti+ ++ + ++ kk + ++ + e+ + ++++ FUN_002263-T1 35 KMRDGVRvhHERKSNGVRVDHERKRDGLSVEHEKKSHGFTIRKSDGVRVHDMKKSNGVRVLHEKKSAGVSVN 106 66665440044566778999999******************9999999899888888877766666665554 PP == domain 3 score: 8.4 bits; conditional E-value: 0.00039 DUF1444 11 eeklkeeevtlkfdreedtlriedkktkkgvtiklke 47 +++ k++ v++ ++r++d +r++++k+ +gv+++ ++ FUN_002263-T1 128 HHEKKRDGVRVYYERKSDGMRVNHEKKSEGVKVDHEK 164 5566788999*********************998654 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 2.5 0.00072 3.7 39 65 .. 20 46 .. 3 59 .. 0.86 2 ? -0.6 0.0 0.51 2.6e+03 24 60 .. 68 104 .. 60 111 .. 0.70 3 ? 6.5 0.3 0.003 16 32 64 .. 120 152 .. 99 159 .. 0.81 4 ? 3.0 0.1 0.038 1.9e+02 39 63 .. 138 162 .. 132 167 .. 0.81 5 ? 2.8 0.5 0.043 2.2e+02 38 59 .. 170 191 .. 154 204 .. 0.55 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00072 DUF2554 39 lrheadsdelravaeesaeGlrehfyw 65 + h+ sd lra e+ +G+r h+ FUN_002263-T1 20 VDHKKKSDRLRADHEKMRDGVRVHHER 46 568999******************974 PP == domain 2 score: -0.6 bits; conditional E-value: 0.51 DUF2554 24 qkdhefvwvktvdhqlrheadsdelravaeesaeGlr 60 +k h f k+ + ++ s+ +r e+ + G+ FUN_002263-T1 68 KKSHGFTIRKSDGVRVHDMKKSNGVRVLHEKKSAGVS 104 5677777777777777777777777777777666665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.003 DUF2554 32 vktvdhqlrheadsdelravaeesaeGlrehfy 64 +k+++ ++ he d +r e ++G+r + FUN_002263-T1 120 IKSGGMRVHHEKKRDGVRVYYERKSDGMRVNHE 152 577888889999999999999999999987765 PP == domain 4 score: 3.0 bits; conditional E-value: 0.038 DUF2554 39 lrheadsdelravaeesaeGlrehf 63 + +e sd +r e+ +eG++ + FUN_002263-T1 138 VYYERKSDGMRVNHEKKSEGVKVDH 162 5678999*************98766 PP == domain 5 score: 2.8 bits; conditional E-value: 0.043 DUF2554 38 qlrheadsdelravaeesaeGl 59 + he sd +r ++G+ FUN_002263-T1 170 TVHHEKKSDGVRLQHAIKSDGV 191 3445555555555555555555 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.1 0.022 1.1e+02 55 77 .. 47 69 .. 39 71 .. 0.87 2 ? 1.8 0.1 0.061 3.1e+02 56 77 .. 89 110 .. 78 111 .. 0.81 3 ? 0.3 0.0 0.19 9.7e+02 57 77 .. 134 154 .. 122 156 .. 0.84 4 ? 1.5 0.1 0.079 4e+02 57 77 .. 156 176 .. 150 178 .. 0.88 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.022 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv v +++ ++l+v +++k FUN_002263-T1 47 KSNGVRVDHERKRDGLSVEHEKK 69 569***************99987 PP == domain 2 score: 1.8 bits; conditional E-value: 0.061 ComGE 56 lNGvevtvkenqeelivlesgk 77 NGv v ++++ +++v +++k FUN_002263-T1 89 SNGVRVLHEKKSAGVSVNHKKK 110 5999999999999999988876 PP == domain 3 score: 0.3 bits; conditional E-value: 0.19 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v +++++++ v +++k FUN_002263-T1 134 DGVRVYYERKSDGMRVNHEKK 154 699999999999999999876 PP == domain 4 score: 1.5 bits; conditional E-value: 0.079 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv+v ++ +++++v +++k FUN_002263-T1 156 EGVKVDHEKRSDGVTVHHEKK 176 699*************99987 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.1 0.0 0.012 63 2 14 .. 2 14 .. 1 16 [. 0.92 2 ? 0.3 0.0 0.2 1e+03 1 13 [. 45 57 .. 45 59 .. 0.90 3 ? -1.2 0.1 0.56 2.9e+03 1 14 [. 56 69 .. 56 70 .. 0.78 4 ? 0.1 0.0 0.22 1.1e+03 3 14 .. 88 99 .. 87 102 .. 0.83 5 ? 1.3 0.1 0.094 4.8e+02 1 14 [. 97 110 .. 97 118 .. 0.87 6 ? 1.3 0.1 0.092 4.7e+02 3 14 .. 121 132 .. 119 133 .. 0.84 7 ? 3.4 0.0 0.02 1e+02 1 14 [. 141 154 .. 141 156 .. 0.93 8 ? 1.1 0.1 0.11 5.4e+02 1 14 [. 152 165 .. 152 167 .. 0.86 9 ? 1.3 0.1 0.096 4.9e+02 2 14 .. 164 176 .. 163 177 .. 0.84 10 ? -0.5 0.1 0.34 1.7e+03 4 13 .. 188 197 .. 187 201 .. 0.80 Alignments for each domain: == domain 1 score: 4.1 bits; conditional E-value: 0.012 Beta-APP 2 RQSAsyEVYHEKl 14 R+S + V HEK+ FUN_002263-T1 2 RKSDGMRVHHEKR 14 8999********8 PP == domain 2 score: 0.3 bits; conditional E-value: 0.2 Beta-APP 1 eRQSAsyEVYHEK 13 eR+S + V HE+ FUN_002263-T1 45 ERKSNGVRVDHER 57 89**********7 PP == domain 3 score: -1.2 bits; conditional E-value: 0.56 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+ + V HEK+ FUN_002263-T1 56 ERKRDGLSVEHEKK 69 5667788899**96 PP == domain 4 score: 0.1 bits; conditional E-value: 0.22 Beta-APP 3 QSAsyEVYHEKl 14 +S + V HEK+ FUN_002263-T1 88 KSNGVRVLHEKK 99 5788899***96 PP == domain 5 score: 1.3 bits; conditional E-value: 0.094 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V H K+ FUN_002263-T1 97 EKKSAGVSVNHKKK 110 679********996 PP == domain 6 score: 1.3 bits; conditional E-value: 0.092 Beta-APP 3 QSAsyEVYHEKl 14 +S + V HEK+ FUN_002263-T1 121 KSGGMRVHHEKK 132 588999****96 PP == domain 7 score: 3.4 bits; conditional E-value: 0.02 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + V HEK+ FUN_002263-T1 141 ERKSDGMRVNHEKK 154 89***********6 PP == domain 8 score: 1.1 bits; conditional E-value: 0.11 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002263-T1 152 EKKSEGVKVDHEKR 165 57789999*****8 PP == domain 9 score: 1.3 bits; conditional E-value: 0.096 Beta-APP 2 RQSAsyEVYHEKl 14 + S + V HEK+ FUN_002263-T1 164 KRSDGVTVHHEKK 176 6788999*****6 PP == domain 10 score: -0.5 bits; conditional E-value: 0.34 Beta-APP 4 SAsyEVYHEK 13 S + V HEK FUN_002263-T1 188 SDGVTVHHEK 197 667789***9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (205 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 951 (0.0372284); expected 510.9 (0.02) Passed bias filter: 362 (0.0141711); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.40 # Mc/sec: 2045.68 // Query: FUN_002264-T1 [L=118] Description: FUN_002264 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.013 16.3 8.4 0.73 10.8 0.8 3.5 4 DUF2554 Protein of unknown function (DUF2554) 0.47 10.6 9.3 4 7.5 0.6 3.7 4 DNA_ligase_A_M ATP dependent DNA ligase domain 0.51 11.0 6.3 38 5.0 0.7 3.8 3 DUF7510 Family of unknown function (DUF7510) 0.53 10.7 4.3 16 6.0 0.1 3.4 4 ComGE Competence system putative prepilin ComGE 2.2 9.6 8.3 12 7.3 3.1 2.2 2 DUF1764 Eukaryotic protein of unknown function (DUF17 4 8.4 12.9 15 6.5 0.4 3.3 3 DUF4467 Domain of unknown function with cystatin-like 5.5 7.5 15.5 45 4.6 0.2 5.6 8 Beta-APP Beta-amyloid peptide (beta-APP) 5.6 7.6 15.0 2.3e+02 2.5 0.1 7.3 9 Tower Tower Domain annotation for each model (and alignments): >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.39 1.3e+03 45 64 .. 4 23 .. 2 29 .. 0.67 2 ? 5.9 0.2 0.0077 25 34 65 .. 26 57 .. 21 63 .. 0.86 3 ? 2.9 0.0 0.067 2.2e+02 39 59 .. 64 84 .. 58 86 .. 0.83 4 ? 10.8 0.8 0.00023 0.73 37 65 .. 84 112 .. 80 118 .] 0.81 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.39 DUF2554 45 sdelravaeesaeGlrehfy 64 sd +r e+ ++G+r + FUN_002264-T1 4 SDGVRVHDEKKSNGVRVVHE 23 67777777777777776554 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0077 DUF2554 34 tvdhqlrheadsdelravaeesaeGlrehfyw 65 +++ ++ h+ sd + e+ ++G+r h+ FUN_002264-T1 26 SAGVRVNHDKKSDGVGVDHEKKSNGVRIHHEK 57 5677889**********************975 PP == domain 3 score: 2.9 bits; conditional E-value: 0.067 DUF2554 39 lrheadsdelravaeesaeGl 59 + he sd +r e+ ++G+ FUN_002264-T1 64 VYHERKSDGVRVNHEKKSDGV 84 679999*****9999999987 PP == domain 4 score: 10.8 bits; conditional E-value: 0.00023 DUF2554 37 hqlrheadsdelravaeesaeGlrehfyw 65 ++ he sd +r e ++G+r h+ FUN_002264-T1 84 VKVDHEKKSDGVRLQHERKSDGVRVHHEK 112 5788**********************963 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.1 0.15 4.7e+02 19 38 .. 17 36 .. 6 42 .. 0.56 2 ? 2.2 0.1 0.053 1.7e+02 24 45 .. 44 65 .. 35 66 .. 0.84 3 ? 7.5 0.6 0.0013 4 18 43 .. 60 85 .. 51 88 .. 0.84 4 ? 5.2 0.2 0.0067 21 25 44 .. 89 108 .. 85 113 .. 0.83 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.15 DNA_ligase_A_M 19 gkafivEiKyDGeRaqvhke 38 g ++ E K G+R+ +k+ FUN_002264-T1 17 GVRVVHEKKSAGVRVNHDKK 36 33444556666666665555 PP == domain 2 score: 2.2 bits; conditional E-value: 0.053 DNA_ligase_A_M 24 vEiKyDGeRaqvhkegdevklf 45 E K +G+R+ +k++d v+++ FUN_002264-T1 44 HEKKSNGVRIHHEKKRDGVSVY 65 5899******999999999876 PP == domain 3 score: 7.5 bits; conditional E-value: 0.0013 DNA_ligase_A_M 18 egkafivEiKyDGeRaqvhkegdevk 43 +g +++ E K DG+R+ +k++d vk FUN_002264-T1 60 DGVSVYHERKSDGVRVNHEKKSDGVK 85 4667899*************999987 PP == domain 4 score: 5.2 bits; conditional E-value: 0.0067 DNA_ligase_A_M 25 EiKyDGeRaqvhkegdevkl 44 E K DG+R+q ++++d v++ FUN_002264-T1 89 EKKSDGVRLQHERKSDGVRV 108 88999999999998888765 PP >> DUF7510 Family of unknown function (DUF7510) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.045 1.4e+02 88 106 .. 13 31 .. 3 42 .. 0.77 2 ? 4.3 0.3 0.02 65 87 107 .. 45 65 .. 32 75 .. 0.74 3 ? 5.0 0.7 0.012 38 74 106 .. 65 97 .. 62 114 .. 0.60 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.045 DUF7510 88 etadGfrivHpepvtdvrl 106 + ++G+r+vH+ + vr+ FUN_002264-T1 13 KKSNGVRVVHEKKSAGVRV 31 5677888888887777776 PP == domain 2 score: 4.3 bits; conditional E-value: 0.02 DUF7510 87 setadGfrivHpepvtdvrll 107 ++ ++G+ri+H+ + v+++ FUN_002264-T1 45 EKKSNGVRIHHEKKRDGVSVY 65 567889999999888877776 PP == domain 3 score: 5.0 bits; conditional E-value: 0.012 DUF7510 74 YqsardseaaeGvsetadGfrivHpepvtdvrl 106 Y++++++ + ++ +dG+++ H+ + vrl FUN_002264-T1 65 YHERKSDGVRVNHEKKSDGVKVDHEKKSDGVRL 97 555555555555555666666666655555554 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.04 1.3e+02 54 77 .. 13 36 .. 7 40 .. 0.85 2 ? 6.0 0.1 0.0051 16 55 77 .. 47 69 .. 40 79 .. 0.90 3 ? 0.4 0.0 0.27 8.7e+02 57 77 .. 71 91 .. 67 93 .. 0.85 4 ? 0.3 0.1 0.29 9.2e+02 57 77 .. 93 113 .. 84 117 .. 0.80 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.04 ComGE 54 LslNGvevtvkenqeelivlesgk 77 + NGv v ++++ ++ v +++k FUN_002264-T1 13 KKSNGVRVVHEKKSAGVRVNHDKK 36 5679****9999999999999887 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0051 ComGE 55 slNGvevtvkenqeelivlesgk 77 + NGv ++ +++ ++++v+++ k FUN_002264-T1 47 KSNGVRIHHEKKRDGVSVYHERK 69 56******************977 PP == domain 3 score: 0.4 bits; conditional E-value: 0.27 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v+ +++++++ v +++k FUN_002264-T1 71 DGVRVNHEKKSDGVKVDHEKK 91 699999999999999999876 PP == domain 4 score: 0.3 bits; conditional E-value: 0.29 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv ++ +++++++ v ++++ FUN_002264-T1 93 DGVRLQHERKSDGVRVHHEKE 113 688889999999999988876 PP >> DUF1764 Eukaryotic protein of unknown function (DUF1764) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 3.1 0.0037 12 28 76 .. 21 67 .. 3 81 .. 0.49 2 ? 5.1 1.3 0.019 60 41 78 .. 77 113 .. 67 117 .. 0.59 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.0037 DUF1764 28 eekeekekkkkkkkkkkkkkkkeeeekfedsk.ekkkrkktedGlpvYte 76 +++k + +++kk++ ++ ++s+ + +++k+ dG++vY+e FUN_002264-T1 21 V---HEKKSAGVRVNHDKKSDGVGVDHEKKSNgVRIHHEKKRDGVSVYHE 67 1...22222222222222222222222222223568889999******87 PP == domain 2 score: 5.1 bits; conditional E-value: 0.019 DUF1764 41 kkkkkkkkkeeeekfedskekkkrkktedGlpvYteee 78 ++kk+ k ++ek +d + ++++++dG++v++e+e FUN_002264-T1 77 HEKKSDGVKVDHEKKSDG-VRLQHERKSDGVRVHHEKE 113 233333333333333333.467888999****999987 PP >> DUF4467 Domain of unknown function with cystatin-like fold (DUF4467) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.7 0.0069 22 19 44 .. 11 36 .. 5 41 .. 0.90 2 ? 6.5 0.4 0.0048 15 19 44 .. 44 69 .. 38 71 .. 0.91 3 ? 3.3 0.6 0.047 1.5e+02 18 40 .. 87 109 .. 71 116 .. 0.59 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0069 DUF4467 19 lakkgnkvrvdiekedaniyVyddgK 44 +kk+n+vrv ek+ a ++V +d K FUN_002264-T1 11 DEKKSNGVRVVHEKKSAGVRVNHDKK 36 589******************98877 PP == domain 2 score: 6.5 bits; conditional E-value: 0.0048 DUF4467 19 lakkgnkvrvdiekedaniyVyddgK 44 +kk+n+vr++ ek+ + Vy++ K FUN_002264-T1 44 HEKKSNGVRIHHEKKRDGVSVYHERK 69 689*******************9877 PP == domain 3 score: 3.3 bits; conditional E-value: 0.047 DUF4467 18 klakkgnkvrvdiekedaniyVy 40 +kk+++vr + e++ ++V+ FUN_002264-T1 87 DHEKKSDGVRLQHERKSDGVRVH 109 34566666666666666555554 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.096 3.1e+02 1 14 [. 12 25 .. 12 27 .. 0.86 2 ? 3.0 0.0 0.045 1.4e+02 1 14 [. 23 36 .. 23 42 .. 0.88 3 ? 0.7 0.0 0.24 7.5e+02 1 14 [. 34 47 .. 34 51 .. 0.85 4 ? 1.1 0.1 0.17 5.6e+02 1 14 [. 45 58 .. 45 59 .. 0.85 5 ? 1.8 0.5 0.11 3.4e+02 6 14 .. 61 69 .. 56 70 .. 0.77 6 ? 3.9 0.1 0.023 75 1 14 [. 67 80 .. 67 84 .. 0.93 7 ? 1.0 0.1 0.18 5.7e+02 1 14 [. 78 91 .. 78 92 .. 0.85 8 ? 4.6 0.2 0.014 45 1 13 [. 100 112 .. 100 116 .. 0.92 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.096 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002264-T1 12 EKKSNGVRVVHEKK 25 67899999****96 PP == domain 2 score: 3.0 bits; conditional E-value: 0.045 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V H+K+ FUN_002264-T1 23 EKKSAGVRVNHDKK 36 689*********97 PP == domain 3 score: 0.7 bits; conditional E-value: 0.24 Beta-APP 1 eRQSAsyEVYHEKl 14 +++S + V HEK+ FUN_002264-T1 34 DKKSDGVGVDHEKK 47 6778899999**96 PP == domain 4 score: 1.1 bits; conditional E-value: 0.17 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + + HEK+ FUN_002264-T1 45 EKKSNGVRIHHEKK 58 57899999****96 PP == domain 5 score: 1.8 bits; conditional E-value: 0.11 Beta-APP 6 syEVYHEKl 14 + VYHE++ FUN_002264-T1 61 GVSVYHERK 69 567****85 PP == domain 6 score: 3.9 bits; conditional E-value: 0.023 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + V HEK+ FUN_002264-T1 67 ERKSDGVRVNHEKK 80 89***********6 PP == domain 7 score: 1.0 bits; conditional E-value: 0.18 Beta-APP 1 eRQSAsyEVYHEKl 14 e++S + V HEK+ FUN_002264-T1 78 EKKSDGVKVDHEKK 91 57899999****96 PP == domain 8 score: 4.6 bits; conditional E-value: 0.014 Beta-APP 1 eRQSAsyEVYHEK 13 eR+S + V HEK FUN_002264-T1 100 ERKSDGVRVHHEK 112 89**********9 PP >> Tower Tower # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 0.14 4.5e+02 2 10 .. 12 20 .. 12 21 .. 0.89 2 ? -0.3 0.0 0.52 1.7e+03 2 10 .. 23 31 .. 22 31 .. 0.86 3 ? -1.8 0.1 1.5 4.9e+03 3 9 .. 35 41 .. 34 42 .. 0.81 4 ? 1.9 0.0 0.11 3.4e+02 2 10 .. 45 53 .. 44 54 .. 0.89 5 ? 2.5 0.1 0.071 2.3e+02 2 11 .. 56 65 .. 55 71 .. 0.88 6 ? 0.1 0.0 0.38 1.2e+03 2 10 .. 67 75 .. 66 75 .. 0.87 7 ? 1.7 0.1 0.13 4e+02 2 10 .. 78 86 .. 77 86 .. 0.88 8 ? 0.7 0.0 0.25 8e+02 2 8 .. 89 95 .. 88 97 .. 0.90 9 ? 0.6 0.0 0.27 8.7e+02 2 10 .. 100 108 .. 99 112 .. 0.89 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.14 Tower 2 EKksdGvfv 10 EKks+Gv v FUN_002264-T1 12 EKKSNGVRV 20 9*****976 PP == domain 2 score: -0.3 bits; conditional E-value: 0.52 Tower 2 EKksdGvfv 10 EKks Gv v FUN_002264-T1 23 EKKSAGVRV 31 9****9865 PP == domain 3 score: -1.8 bits; conditional E-value: 1.5 Tower 3 KksdGvf 9 KksdGv FUN_002264-T1 35 KKSDGVG 41 9****85 PP == domain 4 score: 1.9 bits; conditional E-value: 0.11 Tower 2 EKksdGvfv 10 EKks+Gv + FUN_002264-T1 45 EKKSNGVRI 53 9*****976 PP == domain 5 score: 2.5 bits; conditional E-value: 0.071 Tower 2 EKksdGvfvF 11 EKk dGv+v+ FUN_002264-T1 56 EKKRDGVSVY 65 9******997 PP == domain 6 score: 0.1 bits; conditional E-value: 0.38 Tower 2 EKksdGvfv 10 E+ksdGv v FUN_002264-T1 67 ERKSDGVRV 75 9*****965 PP == domain 7 score: 1.7 bits; conditional E-value: 0.13 Tower 2 EKksdGvfv 10 EKksdGv v FUN_002264-T1 78 EKKSDGVKV 86 9*****966 PP == domain 8 score: 0.7 bits; conditional E-value: 0.25 Tower 2 EKksdGv 8 EKksdGv FUN_002264-T1 89 EKKSDGV 95 9*****7 PP == domain 9 score: 0.6 bits; conditional E-value: 0.27 Tower 2 EKksdGvfv 10 E+ksdGv v FUN_002264-T1 100 ERKSDGVRV 108 9*****977 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (118 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 612 (0.0239577); expected 510.9 (0.02) Passed bias filter: 227 (0.00888628); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 1194.55 // Query: FUN_002265-T1 [L=76] Description: FUN_002265 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (76 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 841 (0.0329223); expected 510.9 (0.02) Passed bias filter: 476 (0.0186338); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.38s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 762.12 // Query: FUN_002266-T1 [L=927] Description: FUN_002266 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.3e-44 146.2 17.5 7.6e-05 23.3 0.0 11.8 11 Ank Ankyrin repeat 1.2e-40 138.4 4.8 1.9e-10 41.6 0.3 5.7 5 Ank_2 Ankyrin repeats (3 copies) 2.4e-36 123.4 7.2 0.00014 22.5 0.1 9.6 10 Ank_4 Ankyrin repeats (many copies) 6.8e-27 93.7 13.7 0.00039 21.2 0.1 8.9 8 Ank_5 Ankyrin repeats (many copies) 6e-20 69.5 6.2 0.044 14.8 0.0 10.9 10 Ank_3 Ankyrin repeat 0.00064 19.9 0.1 0.86 9.8 0.0 3.5 4 Ank_KRIT1 KRIT1 ankyrin-repeats domain 0.0033 18.0 0.0 0.0084 16.7 0.0 1.7 1 Mab-21 Mab-21 protein nucleotidyltransferase domain Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.6 0.0 0.0005 1.8 1 30 [. 43 73 .. 43 76 .. 0.90 2 ! 18.4 0.0 7.4e-07 0.0027 4 30 .. 92 118 .. 92 120 .. 0.88 3 ! 10.8 0.0 0.00021 0.75 15 33 .] 150 168 .. 125 168 .. 0.89 4 ! 18.8 0.3 5.6e-07 0.002 1 32 [. 172 204 .. 172 205 .. 0.91 5 ! 13.4 0.0 3e-05 0.11 3 32 .. 208 237 .. 206 238 .. 0.94 6 ! 23.3 0.0 2.1e-08 7.6e-05 2 32 .. 240 270 .. 239 271 .. 0.91 7 ! 20.3 0.1 1.8e-07 0.00066 3 33 .] 274 310 .. 272 310 .. 0.87 8 ! 7.2 0.1 0.0027 10 2 32 .. 312 346 .. 311 347 .. 0.73 9 ? 4.9 0.0 0.016 57 16 32 .. 414 430 .. 409 431 .. 0.89 10 ! 11.5 0.0 0.00012 0.42 2 32 .. 433 471 .. 432 472 .. 0.88 11 ! 8.3 0.0 0.0012 4.5 1 21 [. 473 493 .. 473 503 .. 0.86 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0005 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvna 30 +G ++L +A+ ++++v+ LLk +Ad+n FUN_002266-T1 43 YGLSALCMAVkAFQSPSLVEKLLKMNADPNF 73 599*******98899********779***95 PP == domain 2 score: 18.4 bits; conditional E-value: 7.4e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvna 30 +PLH+Aa h+ + k LL+ GAd+n FUN_002266-T1 92 SPLHVAAWLRHPGITKVLLDGGADPNT 118 6******999999******547***95 PP == domain 3 score: 10.8 bits; conditional E-value: 0.00021 Ank 15 levvklLLkhGAdvnardk 33 l+v+klL+++GAdv a+d+ FUN_002266-T1 150 LDVMKLLIDNGADVTAVDN 168 67******88******997 PP == domain 4 score: 18.8 bits; conditional E-value: 5.6e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA.dvnard 32 dG + LH+A + gh+ +v++LL+ A dvn+r+ FUN_002266-T1 172 DGTSLLHMATQGGHVLIVNYLLSLRAlDVNCRN 204 7999******************668879**998 PP == domain 5 score: 13.4 bits; conditional E-value: 3e-05 Ank 3 nTPLHlAaraghlevvklL.LkhGAdvnard 32 TPL++A r+++ e+++ L L hGA +n rd FUN_002266-T1 208 ETPLMIALREDRQELLEDLpL-HGAHPNSRD 237 7********************.8******98 PP == domain 6 score: 23.3 bits; conditional E-value: 2.1e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH+A+ + +++ v++L+++ Advn +d FUN_002266-T1 240 GCTALHIAVGRTCVKSVEILIQNSADVNMKD 270 9********778899******878*****99 PP == domain 7 score: 20.3 bits; conditional E-value: 1.8e-07 Ank 3 nTPLHlAaragh......levvklLLkhGAdvnardk 33 +T+LH+A+r ++ ++v+k LL+++Advn+ d+ FUN_002266-T1 274 RTALHVASRLNNsssksnVKVMKSLLSNNADVNVADN 310 7*******6666677778********879*****997 PP == domain 8 score: 7.2 bits; conditional E-value: 0.0027 Ank 2 GnTPLHlAaragh.....levvklLLkhGAdvnard 32 G+ PLHl + ++ + ++ LL+h Ad+ ++d FUN_002266-T1 312 GRRPLHLTVI-DNkdtldMTALECLLEHDADPSLTD 346 888****993.4424744444466**999***9988 PP == domain 9 score: 4.9 bits; conditional E-value: 0.016 Ank 16 evvklLLkhGAdvnard 32 ++++ L+++G+d+n++d FUN_002266-T1 414 KIIRELVEAGVDINCQD 430 699****99******98 PP == domain 10 score: 11.5 bits; conditional E-value: 0.00012 Ank 2 GnTPLHlAa.ragh.......levvklLLkhGAdvnard 32 G T+LH + r+g+ + + LL++GAd nard FUN_002266-T1 433 GSTCLHHTVgRKGRtsshlkfSDFTRVLLDAGADRNARD 471 99*****99977777778999********88*******9 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0012 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP H+Aa+ + + +++L FUN_002266-T1 473 DGNTPAHIAAEGEDADQLRML 493 8*********87778877777 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.7 0.0 4.1e-08 0.00015 18 88 .. 33 118 .. 22 120 .. 0.77 2 ! 41.6 0.3 5.2e-14 1.9e-10 10 90 .] 150 237 .. 145 237 .. 0.89 3 ! 30.5 0.2 1.5e-10 5.6e-07 12 72 .. 222 285 .. 219 288 .. 0.88 4 ! 17.6 0.2 1.7e-06 0.006 8 64 .. 290 353 .. 283 376 .. 0.68 5 ! 27.7 0.0 1.1e-09 4.2e-06 11 80 .. 414 494 .. 409 508 .. 0.82 Alignments for each domain: == domain 1 score: 22.7 bits; conditional E-value: 4.1e-08 Ank_2 18 egadanlqdkngetaLhlAak.nghleivklLlehgad....vndnn.............grtaLhyAaesghleivklLlekgadina 88 e++++n++++ g +aL +A+k ++ +v+ Ll+ +ad + ++Lh+Aa+ +h i k+Ll+ gad+n+ FUN_002266-T1 33 EKQNPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADpnfeS---YigkflgtrktekpSGSPLHVAAWLRHPGITKVLLDGGADPNT 118 678999999************5567899*99999766633440...24444455555555558******************99****97 PP == domain 2 score: 41.6 bits; conditional E-value: 5.2e-14 Ank_2 10 lelvklLl.egadanlqdk...ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+++klL+ +gad+ +d+ +g++ Lh+A + gh+ iv +Ll+ dvn + + +t+L++A +++++e ++ L +ga++n++d FUN_002266-T1 150 LDVMKLLIdNGADVTAVDNtktDGTSLLHMATQGGHVLIVNYLLSLRaLDVNcrNIHEETPLMIALREDRQELLEDLPLHGAHPNSRD 237 6899*********997777799**********************9654667776888********************989***99987 PP == domain 3 score: 30.5 bits; conditional E-value: 1.5e-10 Ank_2 12 lvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesgh 72 l++ L +ga +n++d g taLh+A+ + ++ v++L++++advn d++ rtaLh+A++ ++ FUN_002266-T1 222 LLEDLPlHGAHPNSRDMAGCTALHIAVGRTCVKSVEILIQNSADVNmkDSSCRTALHVASRLNN 285 56666448999999888***********************99999999999********99876 PP == domain 4 score: 17.6 bits; conditional E-value: 1.7e-06 Ank_2 8 gnlelvklLl.egadanlqdkngetaLhlAakng..hlei..vklLlehgadvn..dnngrtaL 64 n +++k Ll ++ad+n+ d++g+ +Lhl + + l++ +++Lleh+ad d r +L FUN_002266-T1 290 SNVKVMKSLLsNNADVNVADNQGRRPLHLTVIDNkdTLDMtaLECLLEHDADPSltDAIERMPL 353 3467888888888888888888888888888866333344556888888554334445555555 PP == domain 5 score: 27.7 bits; conditional E-value: 1.1e-09 Ank_2 11 elvklLl.egadanlqdkngetaLhlAakng.....hlei...vklLlehgadvn..dnngrtaLhyAaesghleivklLl 80 +++++L+ g+d+n+qd +g t Lh+ + + hl++ ++Ll+ gad n d +g+t+ h+Aae + +++L+ FUN_002266-T1 414 KIIRELVeAGVDINCQDIEGSTCLHHTVGRKgrtssHLKFsdfTRVLLDAGADRNarDIDGNTPAHIAAEGEDADQLRMLA 494 4899*********************9998543555455435549*****999988999***********988888888887 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.6 5.9e+03 22 49 .. 36 64 .. 31 71 .. 0.75 2 ? 4.1 0.0 0.025 93 1 40 [. 94 133 .. 93 136 .. 0.84 3 ! 22.5 0.1 3.9e-08 0.00014 7 50 .] 147 193 .. 144 193 .. 0.86 4 ! 10.1 0.0 0.00031 1.1 8 42 .. 184 219 .. 184 226 .. 0.86 5 ! 11.5 0.1 0.00012 0.43 4 39 .. 214 249 .. 211 251 .. 0.86 6 ! 20.9 0.0 1.3e-07 0.00047 9 39 .. 252 282 .. 249 288 .. 0.90 7 ! 16.4 0.0 3.4e-06 0.012 7 35 .. 289 317 .. 286 320 .. 0.94 8 ? -0.7 0.0 0.8 2.9e+03 12 34 .. 331 353 .. 328 359 .. 0.82 9 ! 17.1 0.0 2e-06 0.0072 11 36 .. 414 439 .. 413 449 .. 0.91 10 ! 21.7 0.0 7.5e-08 0.00027 13 49 .. 457 493 .. 446 494 .. 0.93 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.6 Ank_4 22 dinatdgngetaLhfAa.sngnlevlklL 49 ++n ++ +g +aL +A+ ++ +++ ++ L FUN_002266-T1 36 NPNFVNSYGLSALCMAVkAFQSPSLVEKL 64 66777999999999999666666666666 PP == domain 2 score: 4.1 bits; conditional E-value: 0.025 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAasn 40 lh+Aa h + k Ll+ gad+n++ n t+L ++ n FUN_002266-T1 94 LHVAAWLRHPGITKVLLDGGADPNTVaF-NSLTPLLLVLTN 133 6888888999999*************65.589999887765 PP == domain 3 score: 22.5 bits; conditional E-value: 3.9e-08 Ank_4 7 sghlellklLlengadinat.d..gngetaLhfAasngnlevlklLl 50 + l++ klL++ngad+ a+ + +g + Lh+A ++g++ ++ +Ll FUN_002266-T1 147 QAALDVMKLLIDNGADVTAVdNtkTDGTSLLHMATQGGHVLIVNYLL 193 5669************9998434466999**************9997 PP == domain 4 score: 10.1 bits; conditional E-value: 0.00031 Ank_4 8 ghlellklLlen.gadinatdgngetaLhfAasngn 42 gh+ ++ +Ll+ +d+n+++ et+L +A++ + FUN_002266-T1 184 GHVLIVNYLLSLrALDVNCRNIHEETPLMIALREDR 219 79999*****9956*****************98665 PP == domain 5 score: 11.5 bits; conditional E-value: 0.00012 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAas 39 A + ++ell+ L +ga++n +d g taLh+A+ FUN_002266-T1 214 ALREDRQELLEDLPLHGAHPNSRDMAGCTALHIAVG 249 666788899999999*******************95 PP == domain 6 score: 20.9 bits; conditional E-value: 1.3e-07 Ank_4 9 hlellklLlengadinatdgngetaLhfAas 39 +++ ++ L++n ad+n+ d +++taLh A++ FUN_002266-T1 252 CVKSVEILIQNSADVNMKDSSCRTALHVASR 282 7899*************************86 PP == domain 7 score: 16.4 bits; conditional E-value: 3.4e-06 Ank_4 7 sghlellklLlengadinatdgngetaLh 35 ++++++ k+Ll+n ad+n d++g+ +Lh FUN_002266-T1 289 KSNVKVMKSLLSNNADVNVADNQGRRPLH 317 7899************************* PP == domain 8 score: -0.7 bits; conditional E-value: 0.8 Ank_4 12 llklLlengadinatdgngetaL 34 +l+ Lle++ad+ td + +L FUN_002266-T1 331 ALECLLEHDADPSLTDAIERMPL 353 57779*******99998777666 PP == domain 9 score: 17.1 bits; conditional E-value: 2e-06 Ank_4 11 ellklLlengadinatdgngetaLhf 36 ++++ L+e g+din++d +g t+Lh+ FUN_002266-T1 414 KIIRELVEAGVDINCQDIEGSTCLHH 439 57999********************7 PP == domain 10 score: 21.7 bits; conditional E-value: 7.5e-08 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklL 49 + Ll+ gad na+d +g+t+ h+Aa +++ + l++L FUN_002266-T1 457 TRVLLDAGADRNARDIDGNTPAHIAAEGEDADQLRML 493 689*****************************99998 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.00088 3.2 8 43 .. 36 72 .. 31 73 .. 0.88 2 ! 18.8 0.0 6.3e-07 0.0023 18 53 .. 92 127 .. 86 129 .. 0.95 3 ? 4.2 0.0 0.024 88 26 47 .. 147 168 .. 145 171 .. 0.88 4 ! 13.3 0.2 3.3e-05 0.12 14 56 .] 171 214 .. 166 214 .. 0.89 5 ! 21.2 0.1 1.1e-07 0.00039 7 56 .] 233 280 .. 228 280 .. 0.84 6 ? 5.3 0.0 0.011 39 20 54 .. 283 317 .. 283 319 .. 0.82 7 ! 5.8 0.2 0.0072 26 1 54 [. 298 354 .. 298 355 .. 0.72 8 ! 20.1 0.1 2.4e-07 0.00088 1 56 [] 419 481 .. 419 481 .. 0.89 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00088 Ank_5 8 dlnrldgegytpLhvAak.ygaleivrlLlangvdln 43 ++n + +g +L++A+k ++ +v++Ll+ ++d+n FUN_002266-T1 36 NPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADPN 72 677779999*********************8888876 PP == domain 2 score: 18.8 bits; conditional E-value: 6.3e-07 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 pLhvAa+ +++ i ++Ll+ g+d+n+ ++ ltpl FUN_002266-T1 92 SPLHVAAWLRHPGITKVLLDGGADPNTVAFNSLTPL 127 79********************************98 PP == domain 3 score: 4.2 bits; conditional E-value: 0.024 Ank_5 26 ygaleivrlLlangvdlnlkde 47 + al++++lL++ng+d+++ d+ FUN_002266-T1 147 QAALDVMKLLIDNGADVTAVDN 168 6799**************9997 PP == domain 4 score: 13.3 bits; conditional E-value: 3.3e-05 Ank_5 14 gegytpLhvAakygaleivrlLl.angvdlnlkdeegltpldlA 56 ++g+ Lh+A +g+ iv++Ll + d+n+++ + +tpl +A FUN_002266-T1 171 TDGTSLLHMATQGGHVLIVNYLLsLRALDVNCRNIHEETPLMIA 214 457799**********************************9776 PP == domain 5 score: 21.2 bits; conditional E-value: 1.1e-07 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + + g+ t+Lh+A+ + + v++L+ n +d+n+kd+++ t+l++A FUN_002266-T1 233 PNSRDMAGC--TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVA 280 344444445..************************************998 PP == domain 6 score: 5.3 bits; conditional E-value: 0.011 Ank_5 20 LhvAakygaleivrlLlangvdlnlkdeegltpld 54 L++ +++ + +++ Ll n++d+n+ d++g pl+ FUN_002266-T1 283 LNNSSSKSNVKVMKSLLSNNADVNVADNQGRRPLH 317 56677888888999999999999999999987776 PP == domain 7 score: 5.8 bits; conditional E-value: 0.0072 Ank_5 1 LlengpadlnrldgegytpLhvAakyga..leivrlLl..angvdlnlkdeegltpld 54 Ll n ad+n d+ g pLh+ + + l++ l + ++++d+ l+d+ +pl FUN_002266-T1 298 LLSNN-ADVNVADNQGRRPLHLTVIDNKdtLDMTALECllEHDADPSLTDAIERMPLS 354 67776.99999999999****9888665114444444445999999999988777775 PP == domain 8 score: 20.1 bits; conditional E-value: 2.4e-07 Ank_5 1 LlengpadlnrldgegytpLhvAak.yga.......leivrlLlangvdlnlkdeegltpldlA 56 L+e+g +d+n++d eg t+Lh+ + +g+ +++ r+Ll+ g+d n++d +g+tp ++A FUN_002266-T1 419 LVEAG-VDINCQDIEGSTCLHHTVGrKGRtsshlkfSDFTRVLLDAGADRNARDIDGNTPAHIA 481 89999.88888888999********999955555556899**********************98 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.19 6.9e+02 8 30 .. 50 72 .. 43 73 .. 0.72 2 ! 9.2 0.0 0.00082 3 4 30 .. 92 117 .. 90 118 .. 0.95 3 ? 4.4 0.0 0.031 1.1e+02 13 30 .. 148 164 .. 144 165 .. 0.84 4 ! 8.3 0.1 0.0017 6.2 4 30 .. 175 201 .. 172 202 .. 0.87 5 ? 2.6 0.0 0.12 4.5e+02 3 21 .. 208 226 .. 206 235 .. 0.76 6 ! 14.8 0.0 1.2e-05 0.044 2 31 .] 240 268 .. 239 268 .. 0.96 7 ! 10.1 0.0 0.00043 1.6 3 31 .] 274 307 .. 274 307 .. 0.93 8 ? 3.3 0.0 0.069 2.5e+02 2 29 .. 312 342 .. 311 344 .. 0.73 9 ? 1.4 0.0 0.29 1.1e+03 17 31 .] 415 428 .. 410 428 .. 0.89 10 ? 3.4 0.0 0.064 2.3e+02 1 14 [. 473 486 .. 473 497 .. 0.81 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.19 Ank_3 8 lAarngrle.ivklLleklgadin 30 +A++ + + +v+ Ll+ ++ad+n FUN_002266-T1 50 MAVKAFQSPsLVEKLLK-MNADPN 72 55555555559******.****99 PP == domain 2 score: 9.2 bits; conditional E-value: 0.00082 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa ++ i k+Ll+ gad+n FUN_002266-T1 92 SPLHVAAWLRHPGITKVLLD-GGADPN 117 8*******************.*****9 PP == domain 3 score: 4.4 bits; conditional E-value: 0.031 Ank_3 13 grleivklLleklgadin 30 + l+++klL++ +gad+ FUN_002266-T1 148 AALDVMKLLID-NGADVT 164 6789*******.****85 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0017 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 ++Lh+A g++ iv +Ll + d+n FUN_002266-T1 175 SLLHMATQGGHVLIVNYLLSLRALDVN 201 89*****************98777777 PP == domain 5 score: 2.6 bits; conditional E-value: 0.12 Ank_3 3 ntpLhlAarngrleivklL 21 +tpL++A r +r e+++ L FUN_002266-T1 208 ETPLMIALREDRQELLEDL 226 8********9987777655 PP == domain 6 score: 14.8 bits; conditional E-value: 1.2e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+t+Lh+A+ +++ v+ L++ + ad+n+ FUN_002266-T1 240 GCTALHIAVGRTCVKSVEILIQ-NSADVNM 268 89************99******.*****95 PP == domain 7 score: 10.1 bits; conditional E-value: 0.00043 Ank_3 3 ntpLhlAarngrl......eivklLleklgadina 31 +t+Lh+A r ++ +++k Ll ++ad+n+ FUN_002266-T1 274 RTALHVASRLNNSssksnvKVMKSLLS-NNADVNV 307 79***********99998889******.*****95 PP == domain 8 score: 3.3 bits; conditional E-value: 0.069 Ank_3 2 gntpLh.lAarngrl...eivklLleklgadi 29 g+ pLh +++ n + +++++Lle + ad+ FUN_002266-T1 312 GRRPLHlTVIDNKDTldmTALECLLE-HDADP 342 88999955555555564445******.99998 PP == domain 9 score: 1.4 bits; conditional E-value: 0.29 Ank_3 17 ivklLleklgadina 31 i++ L+e g+din+ FUN_002266-T1 415 IIRELVE-AGVDINC 428 89*****.9****96 PP == domain 10 score: 3.4 bits; conditional E-value: 0.064 Ank_3 1 dgntpLhlAarngr 14 dgntp h+Aa+ + FUN_002266-T1 473 DGNTPAHIAAEGED 486 79*******98665 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.048 1.7e+02 42 78 .. 85 121 .. 60 133 .. 0.72 2 ! 9.8 0.0 0.00024 0.86 42 92 .. 169 214 .. 157 226 .. 0.72 3 ? 2.3 0.0 0.047 1.7e+02 87 142 .. 242 297 .. 232 304 .. 0.82 4 ? -3.6 0.0 3.1 1.1e+04 109 128 .. 464 484 .. 457 493 .. 0.63 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.048 Ank_KRIT1 42 ekvddpes.lvaAakgGheevlqlLlalGkadpdPepv 78 ++ + + s l+ Aa+ h ++++Ll+ G+adp+ + FUN_002266-T1 85 KTEKPSGSpLHVAAWLRHPGITKVLLD-GGADPNTVAF 121 4444343459****************8.6688885444 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00024 Ank_KRIT1 42 ekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAa 92 +k+d + l++A++gGh ++++Ll l d + + +++ +tPl+ a FUN_002266-T1 169 TKTDGTSLLHMATQGGHVLIVNYLLSLRALDVNCRNIHE-----ETPLMIA 214 344445558999999999999999999999998666654.....4666555 PP == domain 3 score: 2.3 bits; conditional E-value: 0.047 Ank_KRIT1 87 tPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgenweeeeklLke 142 t l a+Gr +k +++l++++ ++ +t l +a + ++++ + + k++k+ FUN_002266-T1 242 TALHIAVGRTCVKSVEILIQNSADVNMKDSSCRTALHVASRLNNSSSKSNVKVMKS 297 667789***********9976654455559999******99999999999999987 PP == domain 4 score: -3.6 bits; conditional E-value: 3.1 Ank_KRIT1 109 efdptrr.lkgetyleiarer 128 + d++ r + g+t++ ia+e FUN_002266-T1 464 GADRNARdIDGNTPAHIAAEG 484 345554448888888888764 PP >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 2.3e-06 0.0084 3 138 .. 749 891 .. 747 911 .. 0.69 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 2.3e-06 Mab-21 3 enlkvlsPdeFdlvlkLklpeneeiivkedpggpgyvelkltrsg..esndnsrkellsqwleeaegylsaaKvlsrfqslvekalkklekeievn 96 e++k +PdeFd++ +L+ + +++ y+ l +++ s d++ ke ++++l + ++ ls++K++ f l +a l+++++ + FUN_002266-T1 749 EETKLWKPDEFDFMMELTQ--------LKGHSRLEYAGLSRSSNTtvISLDDEMKEMWREFL-K-DDCLSPEKLRDYFVLLTWRAGFSLQRQKY-K 833 789999***********92........2333335555555555223556667999*******.6.89************999999988766555.3 PP Mab-21 97 detlklsykrk.......gpavt.....vaietseeq..............ysVdlvpaielkasWpk 138 + +ls ++ p v+ v ++Vdl++++++++ Wp FUN_002266-T1 834 NLSFNLS--QQsggtgssHPLVRmssvgV-------LlhvqwhgydytsldIDVDLTLSVPFSD-WPV 891 3333333..33668866633333323222.......123333346688899*************.996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (927 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 683 (0.0267371); expected 510.9 (0.02) Passed bias filter: 602 (0.0235663); expected 510.9 (0.02) Passed Vit filter: 47 (0.00183989); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.44u 0.40s 00:00:00.84 Elapsed: 00:00:00.43 # Mc/sec: 8745.00 // Query: FUN_002267-T1 [L=178] Description: FUN_002267 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 425 (0.0166373); expected 510.9 (0.02) Passed bias filter: 410 (0.0160501); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1821.04 // Query: FUN_002268-T1 [L=124] Description: FUN_002268 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-18 65.9 0.4 5.8e-18 65.6 0.4 1.2 1 Histone Core histone H2A/H2B/H3/H4 domain 2e-08 34.5 0.0 2.5e-08 34.1 0.0 1.2 1 Histone_ABTB Histone domain in ABTB family protein 0.0034 18.1 0.0 0.0069 17.1 0.0 1.5 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.051 14.1 0.3 0.06 13.8 0.3 1.2 1 YscO-like YscO-like protein 0.25 12.4 0.0 0.48 11.5 0.0 1.4 1 TFIID_20kDa Transcription initiation factor TFIID subunit Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.6 0.4 1.1e-21 5.8e-18 7 88 .] 22 99 .. 16 99 .. 0.94 Alignments for each domain: == domain 1 score: 65.6 bits; conditional E-value: 1.1e-21 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ +++++++++ ++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_002268-T1 22 AETAKRRRGKRKESYAIYKYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.0 4.9e-12 2.5e-08 23 91 .. 53 123 .. 37 124 .] 0.86 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 4.9e-12 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_002268-T1 53 ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 123 7888888899999999************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.3e-06 0.0069 10 65 .] 42 97 .. 41 97 .. 0.95 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 CBFD_NFYB_HMF 10 rImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_002268-T1 42 KVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 97 899***88888.*****************************************9996 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.3 1.2e-05 0.06 38 113 .. 25 99 .. 6 119 .. 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.2e-05 YscO-like 38 lakleaerdkvlkhkkaKlqqlrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 ++++ +r + + K + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_002268-T1 25 AKRRRGKRKESYAIY--KYKVLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 333333344444444..44445542569******************************************9988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.4e-05 0.48 8 60 .. 43 95 .. 41 99 .. 0.93 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.4e-05 TFIID_20kDa 8 LvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_002268-T1 43 VLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 95 5899***********************************************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 820 (0.0321002); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1257.30 // Query: FUN_002269-T1 [L=232] Description: FUN_002269 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.033 13.5 0.0 0.043 13.1 0.0 1.2 1 ECM29_N Proteasome component ECM29, N-terminal 0.15 13.0 0.1 0.84 10.6 0.0 2.1 2 DUF5905 Family of unknown function (DUF5905) Domain annotation for each model (and alignments): >> ECM29_N Proteasome component ECM29, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 3.4e-06 0.043 329 399 .. 51 119 .. 20 151 .. 0.71 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3.4e-06 ECM29_N 329 KLrslalqFinwvarhgs....ekelkkiapsllsglrkliesqgwpkpseknsseelelrslaYealGllakra 399 + ++ lqF++++ ++g+ ++e++++ap l+++++k+i ++g +k + + ++r+++ + + l+ + FUN_002269-T1 51 LVAQFQLQFFRHYNNKGPplydPNEMEAFAPALFTQILKSILNNGMSKDR------QDTQRKRTLNCFAILLIDD 119 5678889999999999996555555*****************99988873......3456777767766666554 PP >> DUF5905 Family of unknown function (DUF5905) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 6.5e-05 0.84 25 58 .. 12 40 .. 4 56 .. 0.77 2 ? -0.5 0.0 0.18 2.3e+03 19 49 .. 181 210 .. 169 231 .. 0.61 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 6.5e-05 DUF5905 25 sllllayllGketeeYiekleraldalekvrhsk 58 + ++++l Gk ++Yi+k++ +++ ++ + FUN_002269-T1 12 AKDHIQFLKGK--KDYITKVSLIVQIVKTS---R 40 56799******..9*********9998843...3 PP == domain 2 score: -0.5 bits; conditional E-value: 0.18 DUF5905 19 ireekvsllllayllGketeeYieklerald 49 i e++v ++ ++ lG+ +++++++l ++ FUN_002269-T1 181 I-ENRVIQQKMHQALGNMKKPFMNQLPIPML 210 5.55555666666666666666666544443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (232 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1078 (0.0422); expected 510.9 (0.02) Passed bias filter: 752 (0.0294382); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2277.23 // Query: FUN_002273-T1 [L=132] Description: FUN_002273 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0012 19.5 6.3 2.2 8.8 0.3 3.9 4 bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal 0.0021 18.7 3.5 7 7.4 0.1 4.1 4 DUF7348 Domain of unknown function (DUF7348) ------ inclusion threshold ------ 0.02 13.7 0.0 0.43 9.3 0.0 2.0 2 Gp58 gp58-like protein 0.055 14.4 14.1 0.32 11.9 0.7 3.8 4 DUF2554 Protein of unknown function (DUF2554) 0.19 12.7 0.1 8.3 7.4 0.0 2.8 3 Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransfer 0.37 11.3 6.2 2.2 8.9 0.7 3.1 3 DUF4287 Domain of unknown function (DUF4287) 1.4 9.1 8.2 5.3 7.1 0.5 3.2 3 DNA_ligase_A_M ATP dependent DNA ligase domain 1.4 8.6 9.4 0.55 9.9 1.3 3.0 5 DUF632 Protein of unknown function (DUF632) 5.5 7.9 9.2 5.4 8.0 0.2 3.5 4 DUF3761 Protein of unknown function (DUF3761) Domain annotation for each model (and alignments): >> bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0028 7.8 75 108 .. 13 46 .. 6 50 .. 0.82 2 ? 3.3 0.1 0.039 1.1e+02 90 108 .. 50 68 .. 47 71 .. 0.85 3 ! 8.8 0.3 0.00078 2.2 74 108 .. 67 101 .. 65 111 .. 0.85 4 ? 3.8 0.1 0.028 79 74 102 .. 100 128 .. 98 131 .. 0.86 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0028 bCoV_NSP3_N 75 ddyqglplefgasaetvrveeeeeedwlddtteq 108 + +g+ + ++ vrv+ e++ dw+ d e+ FUN_002273-T1 13 NKRDGVRVYHKRKSDGVRVNHEKKSDWVRDDHEK 46 5556777777788999************998775 PP == domain 2 score: 3.3 bits; conditional E-value: 0.039 bCoV_NSP3_N 90 tvrveeeeeedwlddtteq 108 +rv e++ dwl d e+ FUN_002273-T1 50 GLRVHHEKKSDWLRDDHEK 68 589**********998775 PP == domain 3 score: 8.8 bits; conditional E-value: 0.00078 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwlddtteq 108 e +gl + ++ vrv+ e+ dw+ d e+ FUN_002273-T1 67 EKKCDGLRVHHEKKSDGVRVDHEKTSDWVRDDHEK 101 55678999999999**************9887765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.028 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwl 102 e +gl ++ + vrv+ e++e w FUN_002273-T1 100 EKKSDGLSVDHEKKSHGVRVDHEKKERWD 128 5567899999999**************95 PP >> DUF7348 Domain of unknown function (DUF7348) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.23 6.6e+02 20 33 .. 16 31 .. 3 45 .. 0.59 2 ? 5.5 0.0 0.01 29 18 28 .. 47 57 .. 33 66 .. 0.77 3 ! 7.4 0.1 0.0025 7 18 37 .. 69 90 .. 55 101 .. 0.70 4 ? 4.1 0.1 0.028 79 19 45 .. 103 129 .. 93 132 .] 0.71 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.23 DUF7348 20 DGLrv..erdddgYrl 33 DG rv +r++dg r+ FUN_002273-T1 16 DGVRVyhKRKSDGVRV 31 5555533335555554 PP == domain 2 score: 5.5 bits; conditional E-value: 0.01 DUF7348 18 dfDGLrverdd 28 +fDGLrv++++ FUN_002273-T1 47 KFDGLRVHHEK 57 7******8755 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0025 DUF7348 18 dfDGLrver..dddgYrletpd 37 ++DGLrv++ ++dg r++ ++ FUN_002273-T1 69 KCDGLRVHHekKSDGVRVDHEK 90 79*****664588889887433 PP == domain 4 score: 4.1 bits; conditional E-value: 0.028 DUF7348 19 fDGLrverdddgYrletpdeertglse 45 DGL+v+++++ +++ +e+++ +e FUN_002273-T1 103 SDGLSVDHEKKSHGVRVDHEKKERWDE 129 59****997776666655666665555 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.0072 20 218 250 .. 4 36 .. 2 41 .. 0.89 2 ? 9.3 0.0 0.00015 0.43 154 250 .. 28 124 .. 27 126 .. 0.85 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0072 Gp58 218 ssGtteayeskLddlraeftrsnqGmrvelesk 250 s+G ye+k d++r + r + G+rv+ e k FUN_002273-T1 4 SDGVRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 6777888*********************99977 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00015 Gp58 154 GirreyqdadrqlsssyqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveles 249 G+r ++++ + +++ +Gl+ ++ + l+ + + gL +++++ ++ +ts+ + +e+k d+l ++ + + G+rv+ e FUN_002273-T1 28 GVRVNHEKKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKCDGLRVHHEKKSDGVRVDHEKTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEK 123 666666666666777888999999998888888899999999999999999999999999999999999999999999999999999999999887 PP Gp58 250 k 250 k FUN_002273-T1 124 K 124 6 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.5 1.4e+03 45 64 .. 4 23 .. 2 29 .. 0.77 2 ? 10.1 1.2 0.00042 1.2 35 64 .. 27 56 .. 11 60 .. 0.82 3 ? 11.9 0.7 0.00011 0.32 39 64 .. 53 78 .. 51 85 .. 0.90 4 ? 3.7 1.7 0.042 1.2e+02 40 60 .. 98 118 .. 79 131 .. 0.55 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.5 DUF2554 45 sdelravaeesaeGlrehfy 64 sd +r e+ +G+r +++ FUN_002273-T1 4 SDGVRVHYENKRDGVRVYHK 23 78888888888889888775 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00042 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfy 64 + ++ he sd +r e+ +Glr h+ FUN_002273-T1 27 DGVRVNHEKKSDWVRDDHEKKFDGLRVHHE 56 456788**********************97 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00011 DUF2554 39 lrheadsdelravaeesaeGlrehfy 64 + he sd lr e+ +Glr h+ FUN_002273-T1 53 VHHEKKSDWLRDDHEKKCDGLRVHHE 78 67**********************97 PP == domain 4 score: 3.7 bits; conditional E-value: 0.042 DUF2554 40 rheadsdelravaeesaeGlr 60 he sd l e+ + G+r FUN_002273-T1 98 DHEKKSDGLSVDHEKKSHGVR 118 255555555555555555555 PP >> Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransferase RsmF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.0029 8.3 22 69 .. 19 66 .. 10 78 .. 0.70 2 ? 1.9 0.0 0.16 4.4e+02 23 39 .. 75 91 .. 56 108 .. 0.62 3 ? 1.1 0.0 0.28 8e+02 25 44 .. 110 127 .. 88 132 .] 0.70 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0029 Methyltr_RsmF_N 22 aaleeplrkglRvNtlkiskeeleklaa..efelepvpwceeGfyleeee 69 + +++ ++ g+RvN+ k k+++ + + +f+ +v + ++ +l++++ FUN_002273-T1 19 RVYHKRKSDGVRVNHEK--KSDWVRDDHekKFDGLRVHHEKKSDWLRDDH 66 67889999*********..3343333222477788888887777777664 PP == domain 2 score: 1.9 bits; conditional E-value: 0.16 Methyltr_RsmF_N 23 aleeplrkglRvNtlki 39 +e+++ g+Rv + k+ FUN_002273-T1 75 VHHEKKSDGVRVDHEKT 91 33455566666666663 PP == domain 3 score: 1.1 bits; conditional E-value: 0.28 Methyltr_RsmF_N 25 eeplrkglRvNtlkiskeel 44 +e++++g+Rv + k ke++ FUN_002273-T1 110 HEKKSHGVRVDHEK--KERW 127 67788999999999..5555 PP >> DUF4287 Domain of unknown function (DUF4287) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.035 1e+02 28 45 .. 28 45 .. 18 46 .. 0.80 2 ? 8.9 0.7 0.00077 2.2 19 45 .. 38 67 .. 37 68 .. 0.85 3 ? 2.8 0.2 0.062 1.8e+02 30 45 .. 82 100 .. 73 101 .. 0.78 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.035 DUF4287 28 gllvkhgervawLkeehg 45 g v+h++ +w +++h+ FUN_002273-T1 28 GVRVNHEKKSDWVRDDHE 45 34489************6 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00077 DUF4287 19 eWlalveeggll...vkhgervawLkeehg 45 +W++ +e++++ v h++ +wL+++h+ FUN_002273-T1 38 DWVRDDHEKKFDglrVHHEKKSDWLRDDHE 67 6777777888888889*************6 PP == domain 3 score: 2.8 bits; conditional E-value: 0.062 DUF4287 30 l...vkhgervawLkeehg 45 + v h++ +w +++h+ FUN_002273-T1 82 DgvrVDHEKTSDWVRDDHE 100 344489************6 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.5 0.0019 5.3 20 43 .. 7 30 .. 1 43 [. 0.78 2 ? 1.2 0.1 0.13 3.6e+02 25 40 .. 45 60 .. 33 63 .. 0.83 3 ? 4.2 0.2 0.014 41 16 36 .. 69 89 .. 62 97 .. 0.58 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0019 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegdevk 43 +++E K DG+R+ ++++d v+ FUN_002273-T1 7 VRVHYENKRDGVRVYHKRKSDGVR 30 456789999999998888888776 PP == domain 2 score: 1.2 bits; conditional E-value: 0.13 DNA_ligase_A_M 25 EiKyDGeRaqvhkegd 40 E K+DG R+ +k++d FUN_002273-T1 45 EKKFDGLRVHHEKKSD 60 89******99887665 PP == domain 3 score: 4.2 bits; conditional E-value: 0.014 DNA_ligase_A_M 16 klegkafivEiKyDGeRaqvh 36 k++g ++ E K DG+R+ + FUN_002273-T1 69 KCDGLRVHHEKKSDGVRVDHE 89 344444555666666666555 PP >> DUF632 Protein of unknown function (DUF632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.17 4.9e+02 113 142 .. 7 36 .. 3 44 .. 0.56 2 ? 1.8 0.3 0.058 1.6e+02 113 138 .. 29 54 .. 23 59 .. 0.52 3 ? 4.0 0.6 0.013 36 111 136 .. 38 63 .. 32 76 .. 0.56 4 ? 9.9 1.3 0.00019 0.55 108 142 .. 57 91 .. 53 101 .. 0.88 5 ? 2.2 0.5 0.044 1.2e+02 108 142 .. 90 124 .. 86 130 .. 0.81 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.17 DUF632 113 lrieyekkckqLrkleekgaeaskidktra 142 +r+ ye k r +++ + +++ ++ FUN_002273-T1 7 VRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 555555555555555555555555544443 PP == domain 2 score: 1.8 bits; conditional E-value: 0.058 DUF632 113 lrieyekkckqLrkleekgaeaskid 138 +r+++ekk+ r+ ek+ + ++ FUN_002273-T1 29 VRVNHEKKSDWVRDDHEKKFDGLRVH 54 56666666665555555544443333 PP == domain 3 score: 4.0 bits; conditional E-value: 0.013 DUF632 111 eklrieyekkckqLrkleekgaeask 136 + +r ++ekk Lr + ek+ ++ + FUN_002273-T1 38 DWVRDDHEKKFDGLRVHHEKKSDWLR 63 55556666666666655555555433 PP == domain 4 score: 9.9 bits; conditional E-value: 0.00019 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ lr ++ekkc Lr + ek+ + ++d ++ FUN_002273-T1 57 KKSDWLRDDHEKKCDGLRVHHEKKSDGVRVDHEKT 91 789999*********************99997765 PP == domain 5 score: 2.2 bits; conditional E-value: 0.044 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ +r ++ekk+ L ek+ + ++d ++ FUN_002273-T1 90 KTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEKK 124 67788888899999999888888888888887765 PP >> DUF3761 Protein of unknown function (DUF3761) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 0.59 1.7e+03 36 45 .. 5 14 .. 2 29 .. 0.59 2 ? 8.0 0.2 0.0019 5.4 22 57 .. 35 70 .. 25 73 .. 0.85 3 ? 3.9 0.2 0.035 1e+02 23 48 .. 58 83 .. 55 88 .. 0.82 4 ? 2.3 0.3 0.11 3.1e+02 23 47 .. 91 115 .. 83 124 .. 0.80 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.59 DUF3761 36 DGqrvhkPer 45 DG rvh ++ FUN_002273-T1 5 DGVRVHYENK 14 6666665443 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0019 DUF3761 22 eesdLttedsyvnrDGqrvhkPeraksapagatarC 57 ++sd + +d+ DG rvh+ +++ +++ +C FUN_002273-T1 35 KKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKC 70 47999****************999988888888877 PP == domain 3 score: 3.9 bits; conditional E-value: 0.035 DUF3761 23 esdLttedsyvnrDGqrvhkPeraks 48 +sd +d+ DG rvh+ +++ FUN_002273-T1 58 KSDWLRDDHEKKCDGLRVHHEKKSDG 83 688889999999*******9887765 PP == domain 4 score: 2.3 bits; conditional E-value: 0.11 DUF3761 23 esdLttedsyvnrDGqrvhkPerak 47 sd + +d+ +DG v + ++++ FUN_002273-T1 91 TSDWVRDDHEKKSDGLSVDHEKKSH 115 699999**********997766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 930 (0.0364063); expected 510.9 (0.02) Passed bias filter: 365 (0.0142885); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.32u 0.38s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 1284.36 // Query: FUN_002274-T1 [L=120] Description: FUN_002274 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0073 17.2 10.6 1.4 9.8 1.3 3.2 3 DUF2554 Protein of unknown function (DUF2554) ------ inclusion threshold ------ 0.027 14.8 7.3 10 6.5 0.0 4.1 4 Herpes_UL52 Herpesviridae UL52/UL70 DNA primase 0.063 13.7 2.7 13 6.3 0.1 3.1 3 PH_FT_C PH domain found in tandem in fungal proteins 0.066 13.4 8.9 4.3 7.4 0.2 3.6 4 DNA_ligase_A_M ATP dependent DNA ligase domain 0.074 11.9 0.5 7 5.3 0.1 2.6 3 Gp58 gp58-like protein 0.085 13.5 1.4 0.7 10.6 0.2 2.4 3 SdrD_B SdrD B-like domain 0.26 11.3 1.7 1.3 9.0 0.8 2.3 2 DUF1444 Protein of unknown function (DUF1444) 0.47 11.1 11.2 57 4.4 0.1 6.8 8 Tower Tower 1.6 9.2 2.4 26 5.3 0.1 3.2 5 ComGE Competence system putative prepilin ComGE 2.3 9.6 6.4 15 7.0 1.7 2.4 2 DUF1764 Eukaryotic protein of unknown function (DUF17 3.2 8.2 16.7 24 5.4 0.0 5.3 6 Beta-APP Beta-amyloid peptide (beta-APP) Domain annotation for each model (and alignments): >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.6 0.8 0.0063 15 34 64 .. 15 45 .. 3 49 .. 0.73 2 ! 8.2 0.7 0.002 4.7 32 64 .. 35 67 .. 32 75 .. 0.87 3 ! 9.8 1.3 0.00062 1.4 38 65 .. 85 112 .. 78 119 .. 0.84 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0063 DUF2554 34 tvdhqlrheadsdelravaeesaeGlrehfy 64 +++ ++ he sd +r e G r h+ FUN_002274-T1 15 SAGVRVNHEKKSDGVRVHHEIKNGGGRVHHE 45 4556677888888888888888888888876 PP == domain 2 score: 8.2 bits; conditional E-value: 0.002 DUF2554 32 vktvdhqlrheadsdelravaeesaeGlrehfy 64 +k+++ ++ he d +r e ++G+r + FUN_002274-T1 35 IKNGGGRVHHEKKRDGVRVYHERKSDGMRVNHE 67 68999999*******************998775 PP == domain 3 score: 9.8 bits; conditional E-value: 0.00062 DUF2554 38 qlrheadsdelravaeesaeGlrehfyw 65 + he sd +r e ++G+r h+ FUN_002274-T1 85 TVHHEKKSDGVRLQHERKSDGVRVHHEK 112 578**********************963 PP >> Herpes_UL52 Herpesviridae UL52/UL70 DNA primase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.3 0.014 32 24 45 .. 18 39 .. 7 43 .. 0.85 2 ? 3.2 0.1 0.049 1.1e+02 25 44 .. 41 60 .. 40 62 .. 0.82 3 ? 6.5 0.0 0.0045 10 24 48 .. 62 84 .. 57 91 .. 0.85 4 ? 2.5 0.1 0.084 1.9e+02 25 37 .. 96 108 .. 86 114 .. 0.84 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.014 Herpes_UL52 24 lnikhrhksnnvrvfldlrvdk 45 ++++h+ ks++vrv ++++ + FUN_002274-T1 18 VRVNHEKKSDGVRVHHEIKNGG 39 589**********988887765 PP == domain 2 score: 3.2 bits; conditional E-value: 0.049 Herpes_UL52 25 nikhrhksnnvrvfldlrvd 44 ++ h+ k+++vrv+ + ++d FUN_002274-T1 41 RVHHEKKRDGVRVYHERKSD 60 6889*********9776665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0045 Herpes_UL52 24 lnikhrhksnnvrvfldlrvdkesl 48 ++++h+ ks++v+v l+ r+d+ + FUN_002274-T1 62 MRVNHEKKSDGVKVDLEKRSDG--V 84 79*********99998888887..3 PP == domain 4 score: 2.5 bits; conditional E-value: 0.084 Herpes_UL52 25 nikhrhksnnvrv 37 + +h++ks++vrv FUN_002274-T1 96 RLQHERKSDGVRV 108 7799999999997 PP >> PH_FT_C PH domain found in tandem in fungal proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 0.018 43 7 37 .. 8 38 .. 4 41 .. 0.86 2 ? 6.3 0.1 0.0054 13 5 32 .. 39 66 .. 36 76 .. 0.85 3 ? 2.6 0.0 0.077 1.8e+02 18 33 .. 85 100 .. 73 112 .. 0.77 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.018 PH_FT_C 7 eIlddgyehaLrvyrdrksgavRLeasvlrG 37 +++d++ rv +++ks++vR++ +++G FUN_002274-T1 8 RVHDEKKSAGVRVNHEKKSDGVRVHHEIKNG 38 577888888999************9998887 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0054 PH_FT_C 5 sgeIlddgyehaLrvyrdrksgavRLea 32 +g++++++ + rvy++rks+++R++ FUN_002274-T1 39 GGRVHHEKKRDGVRVYHERKSDGMRVNH 66 578999999999*************875 PP == domain 3 score: 2.6 bits; conditional E-value: 0.077 PH_FT_C 18 rvyrdrksgavRLeas 33 +v +++ks++vRL+ FUN_002274-T1 85 TVHHEKKSDGVRLQHE 100 6888889999998854 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.1 0.067 1.6e+02 22 37 .. 20 35 .. 7 44 .. 0.68 2 ? 5.9 1.1 0.0056 13 13 43 .. 34 63 .. 23 65 .. 0.72 3 ? 6.5 0.8 0.0036 8.5 19 43 .. 50 74 .. 43 80 .. 0.81 4 ? 7.4 0.2 0.0019 4.3 19 44 .. 83 108 .. 75 114 .. 0.82 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.067 DNA_ligase_A_M 22 fivEiKyDGeRaqvhk 37 + E K DG+R+ + FUN_002274-T1 20 VNHEKKSDGVRVHHEI 35 4568999999976554 PP == domain 2 score: 5.9 bits; conditional E-value: 0.0056 DNA_ligase_A_M 13 alkklegkafivEiKyDGeRaqvhkegdevk 43 +k+ +g+ ++ E K DG+R+ ++++d ++ FUN_002274-T1 34 EIKN-GGGRVHHEKKRDGVRVYHERKSDGMR 63 4455.46677799999999998888777665 PP == domain 3 score: 6.5 bits; conditional E-value: 0.0036 DNA_ligase_A_M 19 gkafivEiKyDGeRaqvhkegdevk 43 g ++ E K DG R+ +k++d vk FUN_002274-T1 50 GVRVYHERKSDGMRVNHEKKSDGVK 74 5567899999999999999998887 PP == domain 4 score: 7.4 bits; conditional E-value: 0.0019 DNA_ligase_A_M 19 gkafivEiKyDGeRaqvhkegdevkl 44 g +++ E K DG+R+q ++++d v++ FUN_002274-T1 83 GVTVHHEKKSDGVRLQHERKSDGVRV 108 55677899********9999998875 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.022 51 527 550 .. 3 26 .. 1 36 [. 0.86 2 ? 5.3 0.1 0.003 7 226 256 .. 45 75 .. 35 103 .. 0.67 3 ? 2.0 0.0 0.03 69 216 248 .. 79 111 .. 74 115 .. 0.81 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.022 Gp58 527 ssdgidsaesgrfaGirifryasg 550 +sdg+ +++++ aG+r+ + +++ FUN_002274-T1 3 KSDGVRVHDEKKSAGVRVNHEKKS 26 799**************9887765 PP == domain 2 score: 5.3 bits; conditional E-value: 0.003 Gp58 226 eskLddlraeftrsnqGmrveleskisGlqs 256 e+k d++r + r + Gmrv+ e k G++ FUN_002274-T1 45 EKKRDGVRVYHERKSDGMRVNHEKKSDGVKV 75 6666777777777777777777777666553 PP == domain 3 score: 2.0 bits; conditional E-value: 0.03 Gp58 216 ttssGtteayeskLddlraeftrsnqGmrvele 248 + s+G t +e+k d++r ++ r + G+rv e FUN_002274-T1 79 KRSDGVTVHHEKKSDGVRLQHERKSDGVRVHHE 111 568888888999999999999999999998766 PP >> SdrD_B SdrD B-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 0.16 3.7e+02 14 38 .. 5 29 .. 3 51 .. 0.55 2 ? 10.6 0.2 0.0003 0.7 4 42 .. 50 88 .. 47 106 .. 0.83 3 ? 0.5 0.0 0.41 9.5e+02 5 30 .. 84 109 .. 81 114 .. 0.75 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 0.16 SdrD_B 14 nGiqdagekGisgvtvtLkdesgev 38 +G+ ++ek +gv v+ +++s+ v FUN_002274-T1 5 DGVRVHDEKKSAGVRVNHEKKSDGV 29 6666666666667777664443332 PP == domain 2 score: 10.6 bits; conditional E-value: 0.0003 SdrD_B 4 GdfVweDanknGiqdagekGisgvtvtLkdesgevvatt 42 G +V++ + +G+ + ek +gv+v L+++s+ v+ FUN_002274-T1 50 GVRVYHERKSDGMRVNHEKKSDGVKVDLEKRSDGVTVHH 88 6689************************87777665444 PP == domain 3 score: 0.5 bits; conditional E-value: 0.41 SdrD_B 5 dfVweDanknGiqdagekGisgvtvt 30 +V + + +G+ + e +gv v+ FUN_002274-T1 84 VTVHHEKKSDGVRLQHERKSDGVRVH 109 56788888888888888888888886 PP >> DUF1444 Protein of unknown function (DUF1444) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 0.46 1.1e+03 14 34 .. 13 33 .. 3 46 .. 0.56 2 ? 9.0 0.8 0.00054 1.3 12 51 .. 44 83 .. 34 113 .. 0.78 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.46 DUF1444 14 lkeeevtlkfdreedtlried 34 k++ v++++++++d +r+++ FUN_002274-T1 13 KKSAGVRVNHEKKSDGVRVHH 33 333444455555555555544 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00054 DUF1444 12 eklkeeevtlkfdreedtlriedkktkkgvtiklkeliak 51 ++ k++ v++ ++r++d +r++++k+ gv+++l++ + FUN_002274-T1 44 HEKKRDGVRVYHERKSDGMRVNHEKKSDGVKVDLEKRSDG 83 566788899999********************99875443 PP >> Tower Tower # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.1 0.87 2e+03 2 10 .. 12 20 .. 12 20 .. 0.86 2 ? 2.1 0.0 0.13 3e+02 2 10 .. 23 31 .. 22 33 .. 0.89 3 ? 0.8 0.1 0.33 7.7e+02 2 11 .. 45 54 .. 44 59 .. 0.86 4 ? -0.6 0.0 0.92 2.1e+03 2 9 .. 56 63 .. 55 64 .. 0.84 5 ? 1.7 0.1 0.18 4.1e+02 2 10 .. 67 75 .. 66 75 .. 0.88 6 ? 4.4 0.1 0.024 57 1 10 [. 77 86 .. 77 93 .. 0.89 7 ? 0.7 0.0 0.36 8.3e+02 2 8 .. 89 95 .. 88 97 .. 0.90 8 ? 0.7 0.0 0.36 8.3e+02 2 10 .. 100 108 .. 99 114 .. 0.88 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 0.87 Tower 2 EKksdGvfv 10 EKks Gv v FUN_002274-T1 12 EKKSAGVRV 20 9*****865 PP == domain 2 score: 2.1 bits; conditional E-value: 0.13 Tower 2 EKksdGvfv 10 EKksdGv v FUN_002274-T1 23 EKKSDGVRV 31 9*****976 PP == domain 3 score: 0.8 bits; conditional E-value: 0.33 Tower 2 EKksdGvfvF 11 EKk dGv v+ FUN_002274-T1 45 EKKRDGVRVY 54 9*****9886 PP == domain 4 score: -0.6 bits; conditional E-value: 0.92 Tower 2 EKksdGvf 9 E+ksdG+ FUN_002274-T1 56 ERKSDGMR 63 9*****86 PP == domain 5 score: 1.7 bits; conditional E-value: 0.18 Tower 2 EKksdGvfv 10 EKksdGv v FUN_002274-T1 67 EKKSDGVKV 75 9*****966 PP == domain 6 score: 4.4 bits; conditional E-value: 0.024 Tower 1 mEKksdGvfv 10 +EK+sdGv+v FUN_002274-T1 77 LEKRSDGVTV 86 7*******99 PP == domain 7 score: 0.7 bits; conditional E-value: 0.36 Tower 2 EKksdGv 8 EKksdGv FUN_002274-T1 89 EKKSDGV 95 9*****7 PP == domain 8 score: 0.7 bits; conditional E-value: 0.36 Tower 2 EKksdGvfv 10 E+ksdGv v FUN_002274-T1 100 ERKSDGVRV 108 99****977 PP >> ComGE Competence system putative prepilin ComGE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.1 0.36 8.4e+02 57 75 .. 16 34 .. 5 37 .. 0.61 2 ? -0.9 0.0 0.95 2.2e+03 58 77 .. 39 58 .. 21 60 .. 0.73 3 ? 0.5 0.0 0.35 8.1e+02 57 77 .. 49 69 .. 42 71 .. 0.82 4 ? 5.3 0.1 0.011 26 57 77 .. 71 91 .. 62 92 .. 0.88 5 ? -0.5 0.0 0.72 1.7e+03 57 77 .. 93 113 .. 90 116 .. 0.81 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.36 ComGE 57 NGvevtvkenqeelivles 75 Gv v+ +++++++ v ++ FUN_002274-T1 16 AGVRVNHEKKSDGVRVHHE 34 4666666666666666665 PP == domain 2 score: -0.9 bits; conditional E-value: 0.95 ComGE 58 Gvevtvkenqeelivlesgk 77 G v+ +++ +++ v+++ k FUN_002274-T1 39 GGRVHHEKKRDGVRVYHERK 58 55677777778888888765 PP == domain 3 score: 0.5 bits; conditional E-value: 0.35 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv v +++++++ v +++k FUN_002274-T1 49 DGVRVYHERKSDGMRVNHEKK 69 688999999999999998876 PP == domain 4 score: 5.3 bits; conditional E-value: 0.011 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv+v +++ +++++v +++k FUN_002274-T1 71 DGVKVDLEKRSDGVTVHHEKK 91 7****************9987 PP == domain 5 score: -0.5 bits; conditional E-value: 0.72 ComGE 57 NGvevtvkenqeelivlesgk 77 Gv ++ +++++++ v ++++ FUN_002274-T1 93 DGVRLQHERKSDGVRVHHEKE 113 588888899999999988876 PP >> DUF1764 Eukaryotic protein of unknown function (DUF1764) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.0 1.7 0.0065 15 38 76 .. 18 56 .. 2 71 .. 0.55 2 ? 5.0 1.5 0.026 61 32 78 .. 69 113 .. 55 118 .. 0.48 Alignments for each domain: == domain 1 score: 7.0 bits; conditional E-value: 0.0065 DUF1764 38 kkkkkkkkkkkkeeeekfedskekkkrkktedGlpvYte 76 +++kk++ + ++++++ + +++k+ dG++vY+e FUN_002274-T1 18 VRVNHEKKSDGVRVHHEIKNGGGRVHHEKKRDGVRVYHE 56 2223333333334444444444678889999******87 PP == domain 2 score: 5.0 bits; conditional E-value: 0.026 DUF1764 32 ekekkkkkkkkkkkkkkkeeeekfedskekkkrkktedGlpvYteee 78 +++ k + +k+++ + ++e k +d + ++++++dG++v++e+e FUN_002274-T1 69 KSDGVKVDLEKRSDGVTVHHE-KKSDG-VRLQHERKSDGVRVHHEKE 113 222222222222222222222.22222.3577888899999999887 PP >> Beta-APP Beta-amyloid peptide (beta-APP) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.011 24 1 14 [. 12 25 .. 12 29 .. 0.91 2 ? -0.8 0.2 0.96 2.2e+03 9 14 .. 42 47 .. 38 49 .. 0.85 3 ? 1.7 0.5 0.15 3.5e+02 6 14 .. 50 58 .. 45 59 .. 0.77 4 ? 4.3 0.0 0.023 54 1 14 [. 56 69 .. 56 70 .. 0.93 5 ? 2.2 0.1 0.1 2.4e+02 1 14 [. 78 91 .. 78 92 .. 0.84 6 ? 4.5 0.2 0.02 46 1 13 [. 100 112 .. 100 116 .. 0.92 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.011 Beta-APP 1 eRQSAsyEVYHEKl 14 e++SA+ V HEK+ FUN_002274-T1 12 EKKSAGVRVNHEKK 25 689**********6 PP == domain 2 score: -0.8 bits; conditional E-value: 0.96 Beta-APP 9 VYHEKl 14 V HEK+ FUN_002274-T1 42 VHHEKK 47 99**96 PP == domain 3 score: 1.7 bits; conditional E-value: 0.15 Beta-APP 6 syEVYHEKl 14 + VYHE++ FUN_002274-T1 50 GVRVYHERK 58 567****85 PP == domain 4 score: 4.3 bits; conditional E-value: 0.023 Beta-APP 1 eRQSAsyEVYHEKl 14 eR+S + V HEK+ FUN_002274-T1 56 ERKSDGMRVNHEKK 69 89***********6 PP == domain 5 score: 2.2 bits; conditional E-value: 0.1 Beta-APP 1 eRQSAsyEVYHEKl 14 e+ S + V HEK+ FUN_002274-T1 78 EKRSDGVTVHHEKK 91 56788999*****6 PP == domain 6 score: 4.5 bits; conditional E-value: 0.02 Beta-APP 1 eRQSAsyEVYHEK 13 eR+S + V HEK FUN_002274-T1 100 ERKSDGVRVHHEK 112 89**********9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (120 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 677 (0.0265023); expected 510.9 (0.02) Passed bias filter: 306 (0.0119789); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1192.41 // Query: FUN_002275-T1 [L=433] Description: FUN_002275 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-38 129.4 19.2 0.00026 21.6 0.1 9.7 10 Ank Ankyrin repeat 2e-33 115.3 5.5 6.2e-11 43.2 0.3 5.5 5 Ank_2 Ankyrin repeats (3 copies) 4.1e-29 100.5 4.2 5.4e-05 23.9 0.1 8.8 9 Ank_4 Ankyrin repeats (many copies) 7.7e-24 84.0 9.3 0.00068 20.5 0.1 8.1 8 Ank_5 Ankyrin repeats (many copies) 6.1e-21 72.5 5.6 0.094 13.8 0.0 9.6 9 Ank_3 Ankyrin repeat 5.4e-05 23.4 0.0 0.17 12.1 0.0 3.2 3 Ank_KRIT1 KRIT1 ankyrin-repeats domain ------ inclusion threshold ------ 0.1 13.5 0.1 14 6.6 0.0 3.0 3 UDPG_MGDP_dh_C UDP-glucose/GDP-mannose dehydrogenase family, Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.0 0.0002 0.72 1 30 [. 36 66 .. 36 69 .. 0.90 2 ! 19.7 0.0 3e-07 0.0011 4 30 .. 85 111 .. 85 113 .. 0.88 3 ! 12.0 0.0 8.2e-05 0.3 15 33 .] 143 161 .. 118 161 .. 0.89 4 ! 20.1 0.3 2.2e-07 0.0008 1 32 [. 165 197 .. 165 198 .. 0.91 5 ! 14.7 0.0 1.2e-05 0.043 3 32 .. 201 230 .. 199 231 .. 0.94 6 ! 21.4 0.0 8.1e-08 0.0003 2 32 .. 233 263 .. 232 264 .. 0.91 7 ! 21.6 0.1 7e-08 0.00026 3 33 .] 267 303 .. 265 303 .. 0.87 8 ! 8.5 0.1 0.0011 3.9 2 32 .. 305 339 .. 304 340 .. 0.73 9 ? -2.9 0.1 4.8 1.7e+04 21 32 .. 363 375 .. 363 376 .. 0.73 10 ! 5.9 0.0 0.0073 27 16 32 .. 407 423 .. 402 424 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0002 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvna 30 +G ++L +A+ ++++v+ LLk +Ad+n FUN_002275-T1 36 YGLSALCMAVkAFQSPSLVEKLLKMNADPNF 66 599*******98899********779***95 PP == domain 2 score: 19.7 bits; conditional E-value: 3e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvna 30 +PLH+Aa h+ + k LL+ GAd+n FUN_002275-T1 85 SPLHVAAWLRHPGITKVLLDGGADPNT 111 6******999999******547***95 PP == domain 3 score: 12.0 bits; conditional E-value: 8.2e-05 Ank 15 levvklLLkhGAdvnardk 33 l+v+klL+++GAdv a+d+ FUN_002275-T1 143 LDVMKLLIDNGADVTAVDN 161 67******88******997 PP == domain 4 score: 20.1 bits; conditional E-value: 2.2e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA.dvnard 32 dG + LH+A + gh+ +v++LL+ A dvn+r+ FUN_002275-T1 165 DGTSLLHMATQGGHVLIVNYLLSLRAlDVNCRN 197 7999******************668879**998 PP == domain 5 score: 14.7 bits; conditional E-value: 1.2e-05 Ank 3 nTPLHlAaraghlevvklL.LkhGAdvnard 32 TPL++A r+++ e+++ L L hGA +n rd FUN_002275-T1 201 ETPLMIALREDRQELLEDLpL-HGAHPNSRD 230 7********************.8******98 PP == domain 6 score: 21.4 bits; conditional E-value: 8.1e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH+A+ + +++ v++ +++ Advn +d FUN_002275-T1 233 GCTALHIAVGRTCVKSVEIMIQNSADVNMKD 263 9********778899******878*****99 PP == domain 7 score: 21.6 bits; conditional E-value: 7e-08 Ank 3 nTPLHlAaragh......levvklLLkhGAdvnardk 33 +T+LH+A+r ++ ++v+k LL+++Advn+ d+ FUN_002275-T1 267 RTALHVASRLNNsssksnVKVMKSLLSNNADVNVADN 303 7*******6666677778********879*****997 PP == domain 8 score: 8.5 bits; conditional E-value: 0.0011 Ank 2 GnTPLHlAaragh.....levvklLLkhGAdvnard 32 G+ PLHl + ++ + ++ LL+h Ad+ ++d FUN_002275-T1 305 GRRPLHLTVI-DNkdtldMTALECLLEHDADPSLTD 339 888****993.4424744444466**999***9988 PP == domain 9 score: -2.9 bits; conditional E-value: 4.8 Ank 21 LLkhG.Advnard 32 LL++G ++n +d FUN_002275-T1 363 LLSRGcSNLNNKD 375 7877866888877 PP == domain 10 score: 5.9 bits; conditional E-value: 0.0073 Ank 16 evvklLLkhGAdvnard 32 +v++ L+++G+d+n++d FUN_002275-T1 407 KVIRELVEAGVDINCQD 423 699****99******98 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 1.4e-08 5.1e-05 18 88 .. 26 111 .. 16 113 .. 0.77 2 ! 43.2 0.3 1.7e-14 6.2e-11 10 90 .] 143 230 .. 138 230 .. 0.89 3 ! 38.2 0.9 6.4e-13 2.3e-09 14 90 .] 217 302 .. 214 302 .. 0.87 4 ! 19.1 0.2 5.7e-07 0.0021 8 64 .. 283 346 .. 276 368 .. 0.68 5 ? 1.4 0.0 0.19 7.1e+02 74 90 .] 407 423 .. 402 431 .. 0.70 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 1.4e-08 Ank_2 18 egadanlqdkngetaLhlAak.nghleivklLlehgad....vndnn.............grtaLhyAaesghleivklLlekgadina 88 e++++n++++ g +aL +A+k ++ +v+ Ll+ +ad + ++Lh+Aa+ +h i k+Ll+ gad+n+ FUN_002275-T1 26 EKQNPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADpnfeS---YigkflgtrktekpSGSPLHVAAWLRHPGITKVLLDGGADPNT 111 678999999************5567899*99999766633440...24444455555555558******************99****97 PP == domain 2 score: 43.2 bits; conditional E-value: 1.7e-14 Ank_2 10 lelvklLl.egadanlqdk...ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+++klL+ +gad+ +d+ +g++ Lh+A + gh+ iv +Ll+ dvn + + +t+L++A +++++e ++ L +ga++n++d FUN_002275-T1 143 LDVMKLLIdNGADVTAVDNtktDGTSLLHMATQGGHVLIVNYLLSLRaLDVNcrNIHEETPLMIALREDRQELLEDLPLHGAHPNSRD 230 6899*********997777799**********************9654667776888********************989***99987 PP == domain 3 score: 38.2 bits; conditional E-value: 6.4e-13 Ank_2 14 klLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesg......hleivklLlekgadinakd 90 + L +ga +n++d g taLh+A+ + ++ v+++++++advn d++ rtaLh+A++ + +++++k Ll+++ad+n+ d FUN_002275-T1 217 EDLPlHGAHPNSRDMAGCTALHIAVGRTCVKSVEIMIQNSADVNmkDSSCRTALHVASRLNnsssksNVKVMKSLLSNNADVNVAD 302 555347999999888***********************99999999999*********9954555558***************976 PP == domain 4 score: 19.1 bits; conditional E-value: 5.7e-07 Ank_2 8 gnlelvklLl.egadanlqdkngetaLhlAakng..hlei..vklLlehgadvn..dnngrtaL 64 n +++k Ll ++ad+n+ d++g+ +Lhl + + l++ +++Lleh+ad d r +L FUN_002275-T1 283 SNVKVMKSLLsNNADVNVADNQGRRPLHLTVIDNkdTLDMtaLECLLEHDADPSltDAIERMPL 346 3467888888888888888888888888888866333344556888888554334445555555 PP == domain 5 score: 1.4 bits; conditional E-value: 0.19 Ank_2 74 eivklLlekgadinakd 90 ++++ L+e g+din +d FUN_002275-T1 407 KVIRELVEAGVDINCQD 423 56667777777777665 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.54 2e+03 22 49 .. 29 57 .. 24 65 .. 0.66 2 ? 4.4 0.0 0.02 73 1 38 [. 87 124 .. 85 129 .. 0.78 3 ! 23.9 0.1 1.5e-08 5.4e-05 7 50 .] 140 186 .. 137 186 .. 0.86 4 ! 11.5 0.0 0.00012 0.44 8 42 .. 177 212 .. 177 219 .. 0.86 5 ! 12.8 0.1 4.7e-05 0.17 4 39 .. 207 242 .. 204 244 .. 0.86 6 ! 23.8 0.0 1.6e-08 5.9e-05 1 39 [. 237 275 .. 237 281 .. 0.93 7 ! 17.7 0.0 1.3e-06 0.0049 7 35 .. 282 310 .. 279 313 .. 0.94 8 ? 0.6 0.0 0.31 1.1e+03 12 34 .. 324 346 .. 321 353 .. 0.80 9 ! 9.2 0.0 0.00063 2.3 11 30 .. 407 426 .. 406 431 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.54 Ank_4 22 dinatdgngetaLhfAa.sngnlevlklL 49 ++n ++ +g +aL +A+ ++ +++ ++ L FUN_002275-T1 29 NPNFVNSYGLSALCMAVkAFQSPSLVEKL 57 55666778888888887555555555555 PP == domain 2 score: 4.4 bits; conditional E-value: 0.02 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAa 38 lh+Aa h + k Ll+ gad+n++ n t+L ++ FUN_002275-T1 87 LHVAAWLRHPGITKVLLDGGADPNTVaF-NSSTPLLLVL 124 6888888888899999999999999964.4677777665 PP == domain 3 score: 23.9 bits; conditional E-value: 1.5e-08 Ank_4 7 sghlellklLlengadinat.d..gngetaLhfAasngnlevlklLl 50 + l++ klL++ngad+ a+ + +g + Lh+A ++g++ ++ +Ll FUN_002275-T1 140 QAALDVMKLLIDNGADVTAVdNtkTDGTSLLHMATQGGHVLIVNYLL 186 5669************9998434466999**************9997 PP == domain 4 score: 11.5 bits; conditional E-value: 0.00012 Ank_4 8 ghlellklLlen.gadinatdgngetaLhfAasngn 42 gh+ ++ +Ll+ +d+n+++ et+L +A++ + FUN_002275-T1 177 GHVLIVNYLLSLrALDVNCRNIHEETPLMIALREDR 212 79999*****9956*****************98665 PP == domain 5 score: 12.8 bits; conditional E-value: 4.7e-05 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAas 39 A + ++ell+ L +ga++n +d g taLh+A+ FUN_002275-T1 207 ALREDRQELLEDLPLHGAHPNSRDMAGCTALHIAVG 242 666788899999999*******************96 PP == domain 6 score: 23.8 bits; conditional E-value: 1.6e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAas 39 lh A+ + +++ ++ ++n ad+n+ d +++taLh A++ FUN_002275-T1 237 LHIAVGRTCVKSVEIMIQNSADVNMKDSSCRTALHVASR 275 799999*******************************86 PP == domain 7 score: 17.7 bits; conditional E-value: 1.3e-06 Ank_4 7 sghlellklLlengadinatdgngetaLh 35 ++++++ k+Ll+n ad+n d++g+ +Lh FUN_002275-T1 282 KSNVKVMKSLLSNNADVNVADNQGRRPLH 310 7899************************* PP == domain 8 score: 0.6 bits; conditional E-value: 0.31 Ank_4 12 llklLlengadinatdgngetaL 34 +l+ Lle++ad+ td + +L FUN_002275-T1 324 ALECLLEHDADPSLTDAIERMPL 346 577799*****999988776666 PP == domain 9 score: 9.2 bits; conditional E-value: 0.00063 Ank_4 11 ellklLlengadinatdgng 30 ++++ L+e g+din++d +g FUN_002275-T1 407 KVIRELVEAGVDINCQDIEG 426 689*************9977 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.00034 1.3 8 43 .. 29 65 .. 24 66 .. 0.88 2 ! 19.7 0.0 3.3e-07 0.0012 18 53 .. 85 120 .. 79 122 .. 0.94 3 ! 5.4 0.0 0.0099 36 26 47 .. 140 161 .. 138 164 .. 0.88 4 ! 14.9 0.2 1e-05 0.038 13 56 .] 163 207 .. 158 207 .. 0.89 5 ! 20.5 0.1 1.9e-07 0.00068 7 56 .] 226 273 .. 221 273 .. 0.84 6 ! 6.6 0.0 0.0042 15 20 55 .. 276 311 .. 276 312 .. 0.82 7 ! 7.2 0.2 0.0027 9.8 1 54 [. 291 347 .. 291 348 .. 0.72 8 ? 3.1 0.0 0.053 1.9e+02 35 49 .. 412 426 .. 408 431 .. 0.66 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00034 Ank_5 8 dlnrldgegytpLhvAak.ygaleivrlLlangvdln 43 ++n + +g +L++A+k ++ +v++Ll+ ++d+n FUN_002275-T1 29 NPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADPN 65 677779999*********************8888876 PP == domain 2 score: 19.7 bits; conditional E-value: 3.3e-07 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 pLhvAa+ +++ i ++Ll+ g+d+n+ ++ +tpl FUN_002275-T1 85 SPLHVAAWLRHPGITKVLLDGGADPNTVAFNSSTPL 120 79*****************************9**98 PP == domain 3 score: 5.4 bits; conditional E-value: 0.0099 Ank_5 26 ygaleivrlLlangvdlnlkde 47 + al++++lL++ng+d+++ d+ FUN_002275-T1 140 QAALDVMKLLIDNGADVTAVDN 161 6799**************9997 PP == domain 4 score: 14.9 bits; conditional E-value: 1e-05 Ank_5 13 dgegytpLhvAakygaleivrlLl.angvdlnlkdeegltpldlA 56 ++g+ Lh+A +g+ iv++Ll + d+n+++ + +tpl +A FUN_002275-T1 163 KTDGTSLLHMATQGGHVLIVNYLLsLRALDVNCRNIHEETPLMIA 207 4567799**********************************9777 PP == domain 5 score: 20.5 bits; conditional E-value: 1.9e-07 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + + g+ t+Lh+A+ + + v++++ n +d+n+kd+++ t+l++A FUN_002275-T1 226 PNSRDMAGC--TALHIAVGRTCVKSVEIMIQNSADVNMKDSSCRTALHVA 273 444444445..************************************998 PP == domain 6 score: 6.6 bits; conditional E-value: 0.0042 Ank_5 20 LhvAakygaleivrlLlangvdlnlkdeegltpldl 55 L++ +++ + +++ Ll n++d+n+ d++g pl+l FUN_002275-T1 276 LNNSSSKSNVKVMKSLLSNNADVNVADNQGRRPLHL 311 566778888889999999999999999999877765 PP == domain 7 score: 7.2 bits; conditional E-value: 0.0027 Ank_5 1 LlengpadlnrldgegytpLhvAakyga..leivrlLl..angvdlnlkdeegltpld 54 Ll n ad+n d+ g pLh+ + + l++ l + ++++d+ l+d+ +pl FUN_002275-T1 291 LLSNN-ADVNVADNQGRRPLHLTVIDNKdtLDMTALECllEHDADPSLTDAIERMPLS 347 67776.99999999999****9988665124444444445999999999988887775 PP == domain 8 score: 3.1 bits; conditional E-value: 0.053 Ank_5 35 Llangvdlnlkdeeg 49 L++ gvd+n++d eg FUN_002275-T1 412 LVEAGVDINCQDIEG 426 557777888777776 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.075 2.7e+02 8 30 .. 43 65 .. 36 66 .. 0.72 2 ! 10.5 0.0 0.00032 1.2 4 30 .. 85 110 .. 83 111 .. 0.95 3 ? 5.6 0.0 0.013 46 13 30 .. 141 157 .. 137 158 .. 0.84 4 ! 9.5 0.1 0.00066 2.4 4 30 .. 168 194 .. 165 195 .. 0.87 5 ? 3.8 0.0 0.049 1.8e+02 3 21 .. 201 219 .. 199 228 .. 0.75 6 ! 13.8 0.0 2.6e-05 0.094 2 31 .] 233 261 .. 232 261 .. 0.96 7 ! 11.4 0.0 0.00016 0.6 3 31 .] 267 300 .. 267 300 .. 0.93 8 ? 4.6 0.0 0.027 97 2 29 .. 305 335 .. 304 337 .. 0.73 9 ? 2.2 0.0 0.16 5.7e+02 17 31 .] 408 421 .. 403 421 .. 0.89 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.075 Ank_3 8 lAarngrle.ivklLleklgadin 30 +A++ + + +v+ Ll+ ++ad+n FUN_002275-T1 43 MAVKAFQSPsLVEKLLK-MNADPN 65 55555555559******.****99 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00032 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa ++ i k+Ll+ gad+n FUN_002275-T1 85 SPLHVAAWLRHPGITKVLLD-GGADPN 110 8*******************.*****9 PP == domain 3 score: 5.6 bits; conditional E-value: 0.013 Ank_3 13 grleivklLleklgadin 30 + l+++klL++ +gad+ FUN_002275-T1 141 AALDVMKLLID-NGADVT 157 6789*******.****85 PP == domain 4 score: 9.5 bits; conditional E-value: 0.00066 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 ++Lh+A g++ iv +Ll + d+n FUN_002275-T1 168 SLLHMATQGGHVLIVNYLLSLRALDVN 194 89*****************98777777 PP == domain 5 score: 3.8 bits; conditional E-value: 0.049 Ank_3 3 ntpLhlAarngrleivklL 21 +tpL++A r +r e+++ L FUN_002275-T1 201 ETPLMIALREDRQELLEDL 219 8********9987777665 PP == domain 6 score: 13.8 bits; conditional E-value: 2.6e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+t+Lh+A+ +++ v+ +++ + ad+n+ FUN_002275-T1 233 GCTALHIAVGRTCVKSVEIMIQ-NSADVNM 261 89************99******.*****95 PP == domain 7 score: 11.4 bits; conditional E-value: 0.00016 Ank_3 3 ntpLhlAarngrl......eivklLleklgadina 31 +t+Lh+A r ++ +++k Ll ++ad+n+ FUN_002275-T1 267 RTALHVASRLNNSssksnvKVMKSLLS-NNADVNV 300 79***********99998889******.*****95 PP == domain 8 score: 4.6 bits; conditional E-value: 0.027 Ank_3 2 gntpLh.lAarngrl...eivklLleklgadi 29 g+ pLh +++ n + +++++Lle + ad+ FUN_002275-T1 305 GRRPLHlTVIDNKDTldmTALECLLE-HDADP 335 88999955555555564445******.99998 PP == domain 9 score: 2.2 bits; conditional E-value: 0.16 Ank_3 17 ivklLleklgadina 31 +++ L+e g+din+ FUN_002275-T1 408 VIRELVE-AGVDINC 421 79*****.9****96 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.9 0.0 0.0076 28 41 90 .. 77 121 .. 52 129 .. 0.73 2 ! 12.1 0.0 4.7e-05 0.17 42 101 .. 162 216 .. 150 243 .. 0.70 3 ? 2.7 0.0 0.035 1.3e+02 87 142 .. 235 290 .. 219 297 .. 0.81 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0076 Ank_KRIT1 41 rekvddpes.lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPll 90 r++ + + s l+ Aa+ h ++++Ll+ G+adp+ ++ + stPll FUN_002275-T1 77 RKTEKPSGSpLHVAAWLRHPGITKVLLD-GGADPN-----TVAFNSSTPLL 121 54444444459****************8.667887.....33445677776 PP == domain 2 score: 12.1 bits; conditional E-value: 4.7e-05 Ank_KRIT1 42 ekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvi 101 +k+d + l++A++gGh ++++Ll l d + + +++ +tPl+ a ++ +++ FUN_002275-T1 162 TKTDGTSLLHMATQGGHVLIVNYLLSLRALDVNCRNIHE-----ETPLMIALREDRQELL 216 3444455589999**************999999665554.....5888777766666655 PP == domain 3 score: 2.7 bits; conditional E-value: 0.035 Ank_KRIT1 87 tPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgenweeeeklLke 142 t l a+Gr +k ++++++++ ++ +t l +a + ++++ + + k++k+ FUN_002275-T1 235 TALHIAVGRTCVKSVEIMIQNSADVNMKDSSCRTALHVASRLNNSSSKSNVKVMKS 290 667789***********997665445555999999****99999999999999987 PP >> UDPG_MGDP_dh_C UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.0038 14 18 38 .. 141 161 .. 139 179 .. 0.89 2 ? 2.8 0.0 0.061 2.2e+02 20 41 .. 285 306 .. 278 332 .. 0.87 3 ? -1.3 0.0 1.1 4e+03 21 37 .. 407 423 .. 404 427 .. 0.88 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0038 UDPG_MGDP_dh_C 18 paldiieeLkeegaevkvyDP 38 ald+++ L ++ga+v+++D FUN_002275-T1 141 AALDVMKLLIDNGADVTAVDN 161 589****************97 PP == domain 2 score: 2.8 bits; conditional E-value: 0.061 UDPG_MGDP_dh_C 20 ldiieeLkeegaevkvyDPkvk 41 ++++++L++++a+v+v D + + FUN_002275-T1 285 VKVMKSLLSNNADVNVADNQGR 306 799***************8865 PP == domain 3 score: -1.3 bits; conditional E-value: 1.1 UDPG_MGDP_dh_C 21 diieeLkeegaevkvyD 37 ++i+eL e+g++++ D FUN_002275-T1 407 KVIRELVEAGVDINCQD 423 79**********99888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (433 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 615 (0.0240752); expected 510.9 (0.02) Passed bias filter: 520 (0.0203562); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4185.88 // Query: FUN_002276-T1 [L=317] Description: FUN_002276 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-05 24.8 0.0 7.1e-05 23.5 0.0 1.7 1 Ank_4 Ankyrin repeats (many copies) 5.3e-05 23.8 0.0 0.84 10.6 0.0 2.9 2 Ank Ankyrin repeat 0.0034 18.4 0.0 0.0066 17.5 0.0 1.5 1 Ank_2 Ankyrin repeats (3 copies) 0.0095 16.8 0.0 0.022 15.6 0.0 1.6 1 Ank_5 Ankyrin repeats (many copies) Domain annotation for each model (and alignments): >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 1.1e-08 7.1e-05 13 49 .. 26 62 .. 17 63 .. 0.94 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 1.1e-08 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklL 49 + Ll+ gad na+d +g+t+ h+Aa +++ + l++L FUN_002276-T1 26 TRVLLDAGADRNARDIDGNTPAHIAAEGEDADQLRML 62 689*****************************99998 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 0.00013 0.84 4 32 .. 4 40 .. 2 41 .. 0.85 2 ! 10.1 0.0 0.00019 1.2 1 21 [. 42 62 .. 42 72 .. 0.86 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00013 Ank 4 TPLHlAa.ragh.......levvklLLkhGAdvnard 32 T+LH + r+g+ + + LL++GAd nard FUN_002276-T1 4 TCLHHTVgRKGRtsshlkfSDFTRVLLDAGADRNARD 40 999999996677777788899******88*******9 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00019 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP H+Aa+ + + +++L FUN_002276-T1 42 DGNTPAHIAAEGEDADQLRML 62 8*********87778887777 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 1e-06 0.0066 11 62 .. 24 77 .. 4 84 .. 0.72 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1e-06 Ank_2 11 elvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrt 62 ++ + Ll gad n +d +g+t+ h+Aa+ ++ ++ L+++ + ++ + ng+t FUN_002276-T1 24 DFTRVLLdAGADRNARDIDGNTPAHIAAEGEDADQLRMLASETW-QDcpNLNGET 77 56677777888888777788888888888887777888887643.2323355655 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 3.5e-06 0.022 30 56 .] 24 50 .. 23 62 .. 0.90 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 3.5e-06 Ank_5 30 eivrlLlangvdlnlkdeegltpldlA 56 ++ r+Ll+ g+d n++d +g+tp ++A FUN_002276-T1 24 DFTRVLLDAGADRNARDIDGNTPAHIA 50 678999999999999999999999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 709 (0.0277549); expected 510.9 (0.02) Passed bias filter: 615 (0.0240752); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 3104.33 // Query: FUN_002277-T1 [L=184] Description: FUN_002277 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-05 24.7 0.0 5.5e-05 23.8 0.0 1.4 1 Mab-21 Mab-21 protein nucleotidyltransferase domain Domain annotation for each model (and alignments): >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 2.1e-09 5.5e-05 3 139 .. 6 149 .. 4 167 .. 0.72 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 2.1e-09 Mab-21 3 enlkvlsPdeFdlvlkLklpeneeiivkedpggpgyvelkltrsg..esndnsrkellsqwleeaegylsaaKvlsrfqslvekalkklekeievn 96 e++k +PdeFd++ +L+ + + +++p y+ l +++ s d++ ke ++++l + ++ ls++K++ f l +a l+++++ + FUN_002277-T1 6 EETKLWKPDEFDFMMELT--------QLKGHSRPEYAGLSRSSNTtvISLDDEMKEMWREFL-K-DDCLSPEKLRDYFVLLTWRAGFSLQRQKY-K 90 789999************........33444559999999888334788888999*******.6.89************999999988766555.3 PP Mab-21 97 detlklsykrk.......gpavt.....vaietseeq..............ysVdlvpaielkasWpks 139 + +ls ++ p v+ v ++Vdl++++++++ Wp FUN_002277-T1 91 NLSFNLS--QQsggtgssHPLVRmssvgV-------LlhvqwhgydytsldIDVDLTLSVPFSD-WPVL 149 3333333..33668876633333333222.......133333346688899*************.9965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 513 (0.0200822); expected 510.9 (0.02) Passed bias filter: 484 (0.018947); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1829.97 // Query: FUN_002278-T1 [L=178] Description: FUN_002278 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 407 (0.0159327); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 1732.85 // Query: FUN_002279-T1 [L=124] Description: FUN_002279 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-18 65.9 0.4 5.8e-18 65.6 0.4 1.2 1 Histone Core histone H2A/H2B/H3/H4 domain 2e-08 34.5 0.0 2.5e-08 34.1 0.0 1.2 1 Histone_ABTB Histone domain in ABTB family protein 0.0034 18.1 0.0 0.0069 17.1 0.0 1.5 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.051 14.1 0.3 0.06 13.8 0.3 1.2 1 YscO-like YscO-like protein 0.25 12.4 0.0 0.48 11.5 0.0 1.4 1 TFIID_20kDa Transcription initiation factor TFIID subunit Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.6 0.4 1.1e-21 5.8e-18 7 88 .] 22 99 .. 16 99 .. 0.94 Alignments for each domain: == domain 1 score: 65.6 bits; conditional E-value: 1.1e-21 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ +++++++++ ++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_002279-T1 22 AETAKRRRGKRKESYAIYKYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.0 4.9e-12 2.5e-08 23 91 .. 53 123 .. 37 124 .] 0.86 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 4.9e-12 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_002279-T1 53 ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 123 7888888899999999************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.3e-06 0.0069 10 65 .] 42 97 .. 41 97 .. 0.95 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 CBFD_NFYB_HMF 10 rImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_002279-T1 42 KVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 97 899***88888.*****************************************9996 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.3 1.2e-05 0.06 38 113 .. 25 99 .. 6 119 .. 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.2e-05 YscO-like 38 lakleaerdkvlkhkkaKlqqlrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 ++++ +r + + K + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_002279-T1 25 AKRRRGKRKESYAIY--KYKVLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 333333344444444..44445542569******************************************9988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.4e-05 0.48 8 60 .. 43 95 .. 41 99 .. 0.93 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.4e-05 TFIID_20kDa 8 LvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_002279-T1 43 VLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 95 5899***********************************************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 480 (0.0187904); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1246.92 // Query: FUN_002280-T1 [L=103] Description: FUN_002280 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-09 36.5 0.2 8.5e-09 36.0 0.2 1.3 1 CENP-T_C Centromere kinetochore component CENP-T histon 5.3e-06 27.0 0.2 7.8e-06 26.5 0.2 1.3 1 TAF TATA box binding protein associated factor (TA 5.5e-05 24.0 0.4 7.4e-05 23.5 0.4 1.4 1 Histone Core histone H2A/H2B/H3/H4 domain 0.00012 22.8 0.4 0.0002 22.1 0.2 1.6 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a 0.00025 21.9 0.1 0.00044 21.1 0.1 1.5 1 CENP-S CENP-S protein 0.00098 19.7 0.0 0.0012 19.4 0.0 1.1 1 TFIID-31kDa Transcription initiation factor IID, 31kD subu 0.0072 16.8 0.0 0.011 16.2 0.0 1.3 1 Bromo_TP Bromodomain associated ------ inclusion threshold ------ 0.084 13.2 0.2 0.1 12.9 0.2 1.0 1 UPF0137 Uncharacterised protein family (UPF0137) 0.13 12.8 0.1 0.15 12.5 0.1 1.2 1 TAFII28 hTAFII28-like protein conserved region Domain annotation for each model (and alignments): >> CENP-T_C Centromere kinetochore component CENP-T histone fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.0 0.2 3e-12 8.5e-09 19 80 .. 37 96 .. 21 100 .. 0.82 Alignments for each domain: == domain 1 score: 36.0 bits; conditional E-value: 3e-12 CENP-T_C 19 rfarasaiskaklskealealeqasewffeqvseDLeayakHAgRKtidesDvllLlkRqrk 80 r+ar++ + +++s e+ +++ f+e+v D +y++HA+RKt+ Dv+ lkRq++ FUN_002280-T1 37 RLARRG--GVKRISDLIYEKTRGVLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR 96 344442..356788888889999999**********************************75 PP >> TAF TATA box binding protein associated factor (TAF) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.2 2.7e-09 7.8e-06 4 66 .] 30 92 .. 27 92 .. 0.89 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 2.7e-09 TAF 4 ipkesvkvvAeslGianLsdeaaalLaedveyrlkeivqeaakfmrhskRrkLtvaDvdsALr 66 i+k +++ +A G++ +sd + ++ l +++++a+ +++h+kR++ t+ Dv +AL+ FUN_002280-T1 30 ITKPAIRRLARRGGVKRISDLIYEKTRGVLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYALK 92 5677888888888888888888888888889999***************************98 PP >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.4 2.6e-08 7.4e-05 53 87 .. 58 92 .. 16 93 .. 0.88 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 2.6e-08 Histone 53 avedllvelfeeAnllakhaKRvTltpkDiqlAvr 87 +++ +l+++ ++A +++haKR+T+t+ D+ A++ FUN_002280-T1 58 VLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYALK 92 5789**************************99986 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.2 6.9e-08 0.0002 8 65 .] 35 91 .. 28 91 .. 0.85 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 6.9e-08 CBFD_NFYB_HMF 8 vkrImksdpdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 ++r+ + ++++is+ e ++ f+e+v + A+ +++++krKT++a ++ A+ FUN_002280-T1 35 IRRLARRG-GVKRISDLIYEKTRGVLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYAL 91 66777777.7777777777777888999*************************98876 PP >> CENP-S CENP-S protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.1 1.6e-07 0.00044 34 73 .. 47 94 .. 25 97 .. 0.80 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 1.6e-07 CENP-S 34 ltelvykq........lenlakDLeaFAkHAkRstittdDvlLlaRrn 73 +++l+y++ le++ +D ++ +HAkR+t+t+ Dv+ ++r+ FUN_002280-T1 47 ISDLIYEKtrgvlkvfLEKVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 5555555544444444788999*******************9998885 PP >> TFIID-31kDa Transcription initiation factor IID, 31kD subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 4.3e-07 0.0012 13 70 .. 37 94 .. 31 99 .. 0.82 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 4.3e-07 TFIID-31kDa 13 liLkslgieeyeprVvlqLlefayrYttevledAkvysehakkkkidlddvrlAiqsr 70 + + g++ +++ + ++ + + +v++dA +y ehak+k++++ dv A++ + FUN_002280-T1 37 RLARRGGVKRISDLIYEKTRGVLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 94 5556667777777777777777788999************************999865 PP >> Bromo_TP Bromodomain associated # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 3.8e-06 0.011 33 70 .. 56 93 .. 40 99 .. 0.90 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 3.8e-06 Bromo_TP 33 teiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70 +++++ +++++ ++a + eha R ++t Dvv +L++ FUN_002280-T1 56 RGVLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYALKR 93 5778889*****************************98 PP >> UPF0137 Uncharacterised protein family (UPF0137) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.2 3.6e-05 0.1 141 216 .. 23 98 .. 18 101 .. 0.92 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 3.6e-05 UPF0137 141 lkaeveslPrqavYtLasRegslekkeeiienynGetktelleiirktfPlldtdrRqknlsekllellakllklv 216 l+ +++ + + a+ La R g + i e+ +G k l ++ir + +++ +R++ + ++ l++ + + FUN_002280-T1 23 LRDNIQGITKPAIRRLARRGGVKRISDLIYEKTRGVLKVFLEKVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTL 98 7889999**************999999999*********************************9999999877665 PP >> TAFII28 hTAFII28-like protein conserved region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 5.2e-05 0.15 21 72 .. 29 80 .. 18 94 .. 0.88 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 5.2e-05 TAFII28 21 slnkaaikklvnsvlgqsvsqnvaivvaglaKvFvgeiveeAlevqeewges 72 ++ k ai++l+ + + +s+ + +g+ KvF ++ A++ e+ + + FUN_002280-T1 29 GITKPAIRRLARRGGVKRISDLIYEKTRGVLKVFLEKVIRDAVTYTEHAKRK 80 57899**************************************999987655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (103 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 850 (0.0332746); expected 510.9 (0.02) Passed bias filter: 680 (0.0266197); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 9 (0.000352319); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.23u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1054.77 // Query: FUN_002281-T1 [L=99] Description: FUN_002281 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 500 (0.0195733); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.38s 00:00:00.65 Elapsed: 00:00:00.41 # Mc/sec: 983.44 // Query: FUN_002282-T1 [L=232] Description: FUN_002282 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.021 14.1 0.0 0.028 13.7 0.0 1.1 1 ECM29_N Proteasome component ECM29, N-terminal 0.16 12.9 0.1 0.94 10.4 0.0 2.1 2 DUF5905 Family of unknown function (DUF5905) Domain annotation for each model (and alignments): >> ECM29_N Proteasome component ECM29, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 2.2e-06 0.028 329 402 .. 51 122 .. 19 151 .. 0.71 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 2.2e-06 ECM29_N 329 KLrslalqFinwvarhgs....ekelkkiapsllsglrkliesqgwpkpseknsseelelrslaYealGllakrapsl 402 + ++ lqF++++ ++g+ +++++++ap l+++++k+i ++g +k + + ++r+++ + + l+ + + FUN_002282-T1 51 LVAQFQLQFFRHYNNKGPplydPNDMEAFAPALFTQILKSILNNGMSKDR------QDTQRRRTLNCFAILLIDDYHN 122 5678889999999999996665666*****************99988873......3467777777777777555554 PP >> DUF5905 Family of unknown function (DUF5905) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 7.3e-05 0.94 25 55 .. 12 40 .. 4 56 .. 0.77 2 ? -0.4 0.0 0.17 2.2e+03 17 50 .. 179 211 .. 168 231 .. 0.64 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 7.3e-05 DUF5905 25 sllllayllGketeeYiekleraldalekvr 55 + ++++l Gk ++Yi+k++ +++ ++ r FUN_002282-T1 12 AKDHIQFLKGK--KDYITKVSLIVQIVKTSR 40 56799******..9*********99988443 PP == domain 2 score: -0.4 bits; conditional E-value: 0.17 DUF5905 17 GkireekvsllllayllGketeeYiekleralda 50 G i e++v ++ ++ lG+ +++++++l +++ FUN_002282-T1 179 GGI-ENRVIQQKMHQALGNMKKPFMNQLPIPILD 211 555.566666667777777777777766554444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (232 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1015 (0.0397338); expected 510.9 (0.02) Passed bias filter: 747 (0.0292425); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2309.94 // Query: FUN_002283-T1 [L=248] Description: FUN_002283 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (248 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1142 (0.0447054); expected 510.9 (0.02) Passed bias filter: 692 (0.0270894); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.42s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 2469.13 // Query: FUN_002284-T1 [L=62] Description: FUN_002284 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (62 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 541 (0.0211783); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.40s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 633.21 // Query: FUN_002288-T1 [L=132] Description: FUN_002288 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0012 19.5 6.3 2.2 8.8 0.3 3.9 4 bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal 0.0021 18.7 3.5 7 7.4 0.1 4.1 4 DUF7348 Domain of unknown function (DUF7348) ------ inclusion threshold ------ 0.02 13.7 0.0 0.43 9.3 0.0 2.0 2 Gp58 gp58-like protein 0.055 14.4 14.1 0.32 11.9 0.7 3.8 4 DUF2554 Protein of unknown function (DUF2554) 0.19 12.7 0.1 8.3 7.4 0.0 2.8 3 Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransfer 0.37 11.3 6.2 2.2 8.9 0.7 3.1 3 DUF4287 Domain of unknown function (DUF4287) 1.4 9.1 8.2 5.3 7.1 0.5 3.2 3 DNA_ligase_A_M ATP dependent DNA ligase domain 1.4 8.6 9.4 0.55 9.9 1.3 3.0 5 DUF632 Protein of unknown function (DUF632) 5.5 7.9 9.2 5.4 8.0 0.2 3.5 4 DUF3761 Protein of unknown function (DUF3761) Domain annotation for each model (and alignments): >> bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0028 7.8 75 108 .. 13 46 .. 6 50 .. 0.82 2 ? 3.3 0.1 0.039 1.1e+02 90 108 .. 50 68 .. 47 71 .. 0.85 3 ! 8.8 0.3 0.00078 2.2 74 108 .. 67 101 .. 65 111 .. 0.85 4 ? 3.8 0.1 0.028 79 74 102 .. 100 128 .. 98 131 .. 0.86 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0028 bCoV_NSP3_N 75 ddyqglplefgasaetvrveeeeeedwlddtteq 108 + +g+ + ++ vrv+ e++ dw+ d e+ FUN_002288-T1 13 NKRDGVRVYHKRKSDGVRVNHEKKSDWVRDDHEK 46 5556777777788999************998775 PP == domain 2 score: 3.3 bits; conditional E-value: 0.039 bCoV_NSP3_N 90 tvrveeeeeedwlddtteq 108 +rv e++ dwl d e+ FUN_002288-T1 50 GLRVHHEKKSDWLRDDHEK 68 589**********998775 PP == domain 3 score: 8.8 bits; conditional E-value: 0.00078 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwlddtteq 108 e +gl + ++ vrv+ e+ dw+ d e+ FUN_002288-T1 67 EKKCDGLRVHHEKKSDGVRVDHEKTSDWVRDDHEK 101 55678999999999**************9887765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.028 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwl 102 e +gl ++ + vrv+ e++e w FUN_002288-T1 100 EKKSDGLSVDHEKKSHGVRVDHEKKERWD 128 5567899999999**************95 PP >> DUF7348 Domain of unknown function (DUF7348) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.23 6.6e+02 20 33 .. 16 31 .. 3 45 .. 0.59 2 ? 5.5 0.0 0.01 29 18 28 .. 47 57 .. 33 66 .. 0.77 3 ! 7.4 0.1 0.0025 7 18 37 .. 69 90 .. 55 101 .. 0.70 4 ? 4.1 0.1 0.028 79 19 45 .. 103 129 .. 93 132 .] 0.71 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.23 DUF7348 20 DGLrv..erdddgYrl 33 DG rv +r++dg r+ FUN_002288-T1 16 DGVRVyhKRKSDGVRV 31 5555533335555554 PP == domain 2 score: 5.5 bits; conditional E-value: 0.01 DUF7348 18 dfDGLrverdd 28 +fDGLrv++++ FUN_002288-T1 47 KFDGLRVHHEK 57 7******8755 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0025 DUF7348 18 dfDGLrver..dddgYrletpd 37 ++DGLrv++ ++dg r++ ++ FUN_002288-T1 69 KCDGLRVHHekKSDGVRVDHEK 90 79*****664588889887433 PP == domain 4 score: 4.1 bits; conditional E-value: 0.028 DUF7348 19 fDGLrverdddgYrletpdeertglse 45 DGL+v+++++ +++ +e+++ +e FUN_002288-T1 103 SDGLSVDHEKKSHGVRVDHEKKERWDE 129 59****997776666655666665555 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.0072 20 218 250 .. 4 36 .. 2 41 .. 0.89 2 ? 9.3 0.0 0.00015 0.43 154 250 .. 28 124 .. 27 126 .. 0.85 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0072 Gp58 218 ssGtteayeskLddlraeftrsnqGmrvelesk 250 s+G ye+k d++r + r + G+rv+ e k FUN_002288-T1 4 SDGVRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 6777888*********************99977 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00015 Gp58 154 GirreyqdadrqlsssyqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveles 249 G+r ++++ + +++ +Gl+ ++ + l+ + + gL +++++ ++ +ts+ + +e+k d+l ++ + + G+rv+ e FUN_002288-T1 28 GVRVNHEKKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKCDGLRVHHEKKSDGVRVDHEKTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEK 123 666666666666777888999999998888888899999999999999999999999999999999999999999999999999999999999887 PP Gp58 250 k 250 k FUN_002288-T1 124 K 124 6 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.5 1.4e+03 45 64 .. 4 23 .. 2 29 .. 0.77 2 ? 10.1 1.2 0.00042 1.2 35 64 .. 27 56 .. 11 60 .. 0.82 3 ? 11.9 0.7 0.00011 0.32 39 64 .. 53 78 .. 51 85 .. 0.90 4 ? 3.7 1.7 0.042 1.2e+02 40 60 .. 98 118 .. 79 131 .. 0.55 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.5 DUF2554 45 sdelravaeesaeGlrehfy 64 sd +r e+ +G+r +++ FUN_002288-T1 4 SDGVRVHYENKRDGVRVYHK 23 78888888888889888775 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00042 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfy 64 + ++ he sd +r e+ +Glr h+ FUN_002288-T1 27 DGVRVNHEKKSDWVRDDHEKKFDGLRVHHE 56 456788**********************97 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00011 DUF2554 39 lrheadsdelravaeesaeGlrehfy 64 + he sd lr e+ +Glr h+ FUN_002288-T1 53 VHHEKKSDWLRDDHEKKCDGLRVHHE 78 67**********************97 PP == domain 4 score: 3.7 bits; conditional E-value: 0.042 DUF2554 40 rheadsdelravaeesaeGlr 60 he sd l e+ + G+r FUN_002288-T1 98 DHEKKSDGLSVDHEKKSHGVR 118 255555555555555555555 PP >> Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransferase RsmF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.0029 8.3 22 69 .. 19 66 .. 10 78 .. 0.70 2 ? 1.9 0.0 0.16 4.4e+02 23 39 .. 75 91 .. 56 108 .. 0.62 3 ? 1.1 0.0 0.28 8e+02 25 44 .. 110 127 .. 88 132 .] 0.70 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0029 Methyltr_RsmF_N 22 aaleeplrkglRvNtlkiskeeleklaa..efelepvpwceeGfyleeee 69 + +++ ++ g+RvN+ k k+++ + + +f+ +v + ++ +l++++ FUN_002288-T1 19 RVYHKRKSDGVRVNHEK--KSDWVRDDHekKFDGLRVHHEKKSDWLRDDH 66 67889999*********..3343333222477788888887777777664 PP == domain 2 score: 1.9 bits; conditional E-value: 0.16 Methyltr_RsmF_N 23 aleeplrkglRvNtlki 39 +e+++ g+Rv + k+ FUN_002288-T1 75 VHHEKKSDGVRVDHEKT 91 33455566666666663 PP == domain 3 score: 1.1 bits; conditional E-value: 0.28 Methyltr_RsmF_N 25 eeplrkglRvNtlkiskeel 44 +e++++g+Rv + k ke++ FUN_002288-T1 110 HEKKSHGVRVDHEK--KERW 127 67788999999999..5555 PP >> DUF4287 Domain of unknown function (DUF4287) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.035 1e+02 28 45 .. 28 45 .. 18 46 .. 0.80 2 ? 8.9 0.7 0.00077 2.2 19 45 .. 38 67 .. 37 68 .. 0.85 3 ? 2.8 0.2 0.062 1.8e+02 30 45 .. 82 100 .. 73 101 .. 0.78 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.035 DUF4287 28 gllvkhgervawLkeehg 45 g v+h++ +w +++h+ FUN_002288-T1 28 GVRVNHEKKSDWVRDDHE 45 34489************6 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00077 DUF4287 19 eWlalveeggll...vkhgervawLkeehg 45 +W++ +e++++ v h++ +wL+++h+ FUN_002288-T1 38 DWVRDDHEKKFDglrVHHEKKSDWLRDDHE 67 6777777888888889*************6 PP == domain 3 score: 2.8 bits; conditional E-value: 0.062 DUF4287 30 l...vkhgervawLkeehg 45 + v h++ +w +++h+ FUN_002288-T1 82 DgvrVDHEKTSDWVRDDHE 100 344489************6 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.5 0.0019 5.3 20 43 .. 7 30 .. 1 43 [. 0.78 2 ? 1.2 0.1 0.13 3.6e+02 25 40 .. 45 60 .. 33 63 .. 0.83 3 ? 4.2 0.2 0.014 41 16 36 .. 69 89 .. 62 97 .. 0.58 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0019 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegdevk 43 +++E K DG+R+ ++++d v+ FUN_002288-T1 7 VRVHYENKRDGVRVYHKRKSDGVR 30 456789999999998888888776 PP == domain 2 score: 1.2 bits; conditional E-value: 0.13 DNA_ligase_A_M 25 EiKyDGeRaqvhkegd 40 E K+DG R+ +k++d FUN_002288-T1 45 EKKFDGLRVHHEKKSD 60 89******99887665 PP == domain 3 score: 4.2 bits; conditional E-value: 0.014 DNA_ligase_A_M 16 klegkafivEiKyDGeRaqvh 36 k++g ++ E K DG+R+ + FUN_002288-T1 69 KCDGLRVHHEKKSDGVRVDHE 89 344444555666666666555 PP >> DUF632 Protein of unknown function (DUF632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.17 4.9e+02 113 142 .. 7 36 .. 3 44 .. 0.56 2 ? 1.8 0.3 0.058 1.6e+02 113 138 .. 29 54 .. 23 59 .. 0.52 3 ? 4.0 0.6 0.013 36 111 136 .. 38 63 .. 32 76 .. 0.56 4 ? 9.9 1.3 0.00019 0.55 108 142 .. 57 91 .. 53 101 .. 0.88 5 ? 2.2 0.5 0.044 1.2e+02 108 142 .. 90 124 .. 86 130 .. 0.81 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.17 DUF632 113 lrieyekkckqLrkleekgaeaskidktra 142 +r+ ye k r +++ + +++ ++ FUN_002288-T1 7 VRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 555555555555555555555555544443 PP == domain 2 score: 1.8 bits; conditional E-value: 0.058 DUF632 113 lrieyekkckqLrkleekgaeaskid 138 +r+++ekk+ r+ ek+ + ++ FUN_002288-T1 29 VRVNHEKKSDWVRDDHEKKFDGLRVH 54 56666666665555555544443333 PP == domain 3 score: 4.0 bits; conditional E-value: 0.013 DUF632 111 eklrieyekkckqLrkleekgaeask 136 + +r ++ekk Lr + ek+ ++ + FUN_002288-T1 38 DWVRDDHEKKFDGLRVHHEKKSDWLR 63 55556666666666655555555433 PP == domain 4 score: 9.9 bits; conditional E-value: 0.00019 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ lr ++ekkc Lr + ek+ + ++d ++ FUN_002288-T1 57 KKSDWLRDDHEKKCDGLRVHHEKKSDGVRVDHEKT 91 789999*********************99997765 PP == domain 5 score: 2.2 bits; conditional E-value: 0.044 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ +r ++ekk+ L ek+ + ++d ++ FUN_002288-T1 90 KTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEKK 124 67788888899999999888888888888887765 PP >> DUF3761 Protein of unknown function (DUF3761) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 0.59 1.7e+03 36 45 .. 5 14 .. 2 29 .. 0.59 2 ? 8.0 0.2 0.0019 5.4 22 57 .. 35 70 .. 25 73 .. 0.85 3 ? 3.9 0.2 0.035 1e+02 23 48 .. 58 83 .. 55 88 .. 0.82 4 ? 2.3 0.3 0.11 3.1e+02 23 47 .. 91 115 .. 83 124 .. 0.80 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.59 DUF3761 36 DGqrvhkPer 45 DG rvh ++ FUN_002288-T1 5 DGVRVHYENK 14 6666665443 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0019 DUF3761 22 eesdLttedsyvnrDGqrvhkPeraksapagatarC 57 ++sd + +d+ DG rvh+ +++ +++ +C FUN_002288-T1 35 KKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKC 70 47999****************999988888888877 PP == domain 3 score: 3.9 bits; conditional E-value: 0.035 DUF3761 23 esdLttedsyvnrDGqrvhkPeraks 48 +sd +d+ DG rvh+ +++ FUN_002288-T1 58 KSDWLRDDHEKKCDGLRVHHEKKSDG 83 688889999999*******9887765 PP == domain 4 score: 2.3 bits; conditional E-value: 0.11 DUF3761 23 esdLttedsyvnrDGqrvhkPerak 47 sd + +d+ +DG v + ++++ FUN_002288-T1 91 TSDWVRDDHEKKSDGLSVDHEKKSH 115 699999**********997766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 930 (0.0364063); expected 510.9 (0.02) Passed bias filter: 365 (0.0142885); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.30u 0.36s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1332.17 // Query: FUN_002289-T1 [L=436] Description: FUN_002289 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-38 129.3 19.2 0.00026 21.6 0.1 9.7 10 Ank Ankyrin repeat 2.2e-33 115.2 5.5 6.3e-11 43.2 0.3 5.5 5 Ank_2 Ankyrin repeats (3 copies) 4.4e-29 100.4 4.2 5.5e-05 23.9 0.1 8.8 9 Ank_4 Ankyrin repeats (many copies) 8.2e-24 83.9 9.3 0.00068 20.4 0.1 8.1 8 Ank_5 Ankyrin repeats (many copies) 6.6e-21 72.4 5.6 0.095 13.8 0.0 9.6 9 Ank_3 Ankyrin repeat 5.6e-05 23.4 0.0 0.17 12.1 0.0 3.2 3 Ank_KRIT1 KRIT1 ankyrin-repeats domain ------ inclusion threshold ------ 0.1 13.4 0.1 14 6.6 0.0 3.0 3 UDPG_MGDP_dh_C UDP-glucose/GDP-mannose dehydrogenase family, Domain annotation for each model (and alignments): >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.0 0.0002 0.73 1 30 [. 39 69 .. 39 72 .. 0.90 2 ! 19.7 0.0 3e-07 0.0011 4 30 .. 88 114 .. 88 116 .. 0.88 3 ! 12.0 0.0 8.3e-05 0.3 15 33 .] 146 164 .. 121 164 .. 0.89 4 ! 20.1 0.3 2.2e-07 0.00081 1 32 [. 168 200 .. 168 201 .. 0.91 5 ! 14.6 0.0 1.2e-05 0.044 3 32 .. 204 233 .. 202 234 .. 0.94 6 ! 21.4 0.0 8.2e-08 0.0003 2 32 .. 236 266 .. 235 267 .. 0.91 7 ! 21.6 0.1 7.1e-08 0.00026 3 33 .] 270 306 .. 268 306 .. 0.87 8 ! 8.5 0.1 0.0011 3.9 2 32 .. 308 342 .. 307 343 .. 0.73 9 ? -3.0 0.1 4.8 1.8e+04 21 32 .. 366 378 .. 366 379 .. 0.73 10 ! 5.9 0.0 0.0074 27 16 32 .. 410 426 .. 405 427 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0002 Ank 1 dGnTPLHlAa.raghlevvklLLkhGAdvna 30 +G ++L +A+ ++++v+ LLk +Ad+n FUN_002289-T1 39 YGLSALCMAVkAFQSPSLVEKLLKMNADPNF 69 599*******98899********779***95 PP == domain 2 score: 19.7 bits; conditional E-value: 3e-07 Ank 4 TPLHlAaraghlevvklLLkhGAdvna 30 +PLH+Aa h+ + k LL+ GAd+n FUN_002289-T1 88 SPLHVAAWLRHPGITKVLLDGGADPNT 114 6******999999******547***95 PP == domain 3 score: 12.0 bits; conditional E-value: 8.3e-05 Ank 15 levvklLLkhGAdvnardk 33 l+v+klL+++GAdv a+d+ FUN_002289-T1 146 LDVMKLLIDNGADVTAVDN 164 67******88******997 PP == domain 4 score: 20.1 bits; conditional E-value: 2.2e-07 Ank 1 dGnTPLHlAaraghlevvklLLkhGA.dvnard 32 dG + LH+A + gh+ +v++LL+ A dvn+r+ FUN_002289-T1 168 DGTSLLHMATQGGHVLIVNYLLSLRAlDVNCRN 200 7999******************668879**998 PP == domain 5 score: 14.6 bits; conditional E-value: 1.2e-05 Ank 3 nTPLHlAaraghlevvklL.LkhGAdvnard 32 TPL++A r+++ e+++ L L hGA +n rd FUN_002289-T1 204 ETPLMIALREDRQELLEDLpL-HGAHPNSRD 233 7********************.8******98 PP == domain 6 score: 21.4 bits; conditional E-value: 8.2e-08 Ank 2 GnTPLHlAaraghlevvklLLkhGAdvnard 32 G+T+LH+A+ + +++ v++ +++ Advn +d FUN_002289-T1 236 GCTALHIAVGRTCVKSVEIMIQNSADVNMKD 266 9********778899******878*****99 PP == domain 7 score: 21.6 bits; conditional E-value: 7.1e-08 Ank 3 nTPLHlAaragh......levvklLLkhGAdvnardk 33 +T+LH+A+r ++ ++v+k LL+++Advn+ d+ FUN_002289-T1 270 RTALHVASRLNNsssksnVKVMKSLLSNNADVNVADN 306 7*******6666677778********879*****997 PP == domain 8 score: 8.5 bits; conditional E-value: 0.0011 Ank 2 GnTPLHlAaragh.....levvklLLkhGAdvnard 32 G+ PLHl + ++ + ++ LL+h Ad+ ++d FUN_002289-T1 308 GRRPLHLTVI-DNkdtldMTALECLLEHDADPSLTD 342 888****993.4424744444466**999***9988 PP == domain 9 score: -3.0 bits; conditional E-value: 4.8 Ank 21 LLkhG.Advnard 32 LL++G ++n +d FUN_002289-T1 366 LLSRGcSNLNNKD 378 7877866888877 PP == domain 10 score: 5.9 bits; conditional E-value: 0.0074 Ank 16 evvklLLkhGAdvnard 32 +v++ L+++G+d+n++d FUN_002289-T1 410 KVIRELVEAGVDINCQD 426 699****99******98 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 1.4e-08 5.2e-05 18 88 .. 29 114 .. 19 116 .. 0.77 2 ! 43.2 0.3 1.7e-14 6.3e-11 10 90 .] 146 233 .. 141 233 .. 0.89 3 ! 38.1 0.9 6.5e-13 2.4e-09 14 90 .] 220 305 .. 217 305 .. 0.87 4 ! 19.1 0.2 5.8e-07 0.0021 8 64 .. 286 349 .. 279 371 .. 0.68 5 ? 1.3 0.0 0.2 7.1e+02 74 90 .] 410 426 .. 405 434 .. 0.70 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 1.4e-08 Ank_2 18 egadanlqdkngetaLhlAak.nghleivklLlehgad....vndnn.............grtaLhyAaesghleivklLlekgadina 88 e++++n++++ g +aL +A+k ++ +v+ Ll+ +ad + ++Lh+Aa+ +h i k+Ll+ gad+n+ FUN_002289-T1 29 EKQNPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADpnfeS---YigkflgtrktekpSGSPLHVAAWLRHPGITKVLLDGGADPNT 114 678999999************5567899*99999766633440...24444455555555558******************99****97 PP == domain 2 score: 43.2 bits; conditional E-value: 1.7e-14 Ank_2 10 lelvklLl.egadanlqdk...ngetaLhlAaknghleivklLlehg.advn..dnngrtaLhyAaesghleivklLlekgadinakd 90 l+++klL+ +gad+ +d+ +g++ Lh+A + gh+ iv +Ll+ dvn + + +t+L++A +++++e ++ L +ga++n++d FUN_002289-T1 146 LDVMKLLIdNGADVTAVDNtktDGTSLLHMATQGGHVLIVNYLLSLRaLDVNcrNIHEETPLMIALREDRQELLEDLPLHGAHPNSRD 233 6899*********997777799**********************9654667776888********************989***99987 PP == domain 3 score: 38.1 bits; conditional E-value: 6.5e-13 Ank_2 14 klLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrtaLhyAaesg......hleivklLlekgadinakd 90 + L +ga +n++d g taLh+A+ + ++ v+++++++advn d++ rtaLh+A++ + +++++k Ll+++ad+n+ d FUN_002289-T1 220 EDLPlHGAHPNSRDMAGCTALHIAVGRTCVKSVEIMIQNSADVNmkDSSCRTALHVASRLNnsssksNVKVMKSLLSNNADVNVAD 305 555347999999888***********************99999999999*********9954555558***************976 PP == domain 4 score: 19.1 bits; conditional E-value: 5.8e-07 Ank_2 8 gnlelvklLl.egadanlqdkngetaLhlAakng..hlei..vklLlehgadvn..dnngrtaL 64 n +++k Ll ++ad+n+ d++g+ +Lhl + + l++ +++Lleh+ad d r +L FUN_002289-T1 286 SNVKVMKSLLsNNADVNVADNQGRRPLHLTVIDNkdTLDMtaLECLLEHDADPSltDAIERMPL 349 3467888888888888888888888888888866333344556888888554334445555555 PP == domain 5 score: 1.3 bits; conditional E-value: 0.2 Ank_2 74 eivklLlekgadinakd 90 ++++ L+e g+din +d FUN_002289-T1 410 KVIRELVEAGVDINCQD 426 56667777777777665 PP >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.55 2e+03 22 49 .. 32 60 .. 27 68 .. 0.66 2 ? 4.4 0.0 0.02 74 1 38 [. 90 127 .. 88 132 .. 0.78 3 ! 23.9 0.1 1.5e-08 5.5e-05 7 50 .] 143 189 .. 140 189 .. 0.86 4 ! 11.4 0.0 0.00012 0.45 8 42 .. 180 215 .. 180 222 .. 0.86 5 ! 12.8 0.1 4.7e-05 0.17 4 39 .. 210 245 .. 207 247 .. 0.86 6 ! 23.7 0.0 1.6e-08 6e-05 1 39 [. 240 278 .. 240 284 .. 0.93 7 ! 17.6 0.0 1.4e-06 0.005 7 35 .. 285 313 .. 282 316 .. 0.94 8 ? 0.6 0.0 0.31 1.1e+03 12 34 .. 327 349 .. 324 356 .. 0.80 9 ! 9.2 0.0 0.00063 2.3 11 30 .. 410 429 .. 409 434 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.55 Ank_4 22 dinatdgngetaLhfAa.sngnlevlklL 49 ++n ++ +g +aL +A+ ++ +++ ++ L FUN_002289-T1 32 NPNFVNSYGLSALCMAVkAFQSPSLVEKL 60 55666778888888887555555555555 PP == domain 2 score: 4.4 bits; conditional E-value: 0.02 Ank_4 1 lhaAaksghlellklLlengadinat.dgngetaLhfAa 38 lh+Aa h + k Ll+ gad+n++ n t+L ++ FUN_002289-T1 90 LHVAAWLRHPGITKVLLDGGADPNTVaF-NSSTPLLLVL 127 6888888888899999999999999964.4677777665 PP == domain 3 score: 23.9 bits; conditional E-value: 1.5e-08 Ank_4 7 sghlellklLlengadinat.d..gngetaLhfAasngnlevlklLl 50 + l++ klL++ngad+ a+ + +g + Lh+A ++g++ ++ +Ll FUN_002289-T1 143 QAALDVMKLLIDNGADVTAVdNtkTDGTSLLHMATQGGHVLIVNYLL 189 5669************9998434466999**************9997 PP == domain 4 score: 11.4 bits; conditional E-value: 0.00012 Ank_4 8 ghlellklLlen.gadinatdgngetaLhfAasngn 42 gh+ ++ +Ll+ +d+n+++ et+L +A++ + FUN_002289-T1 180 GHVLIVNYLLSLrALDVNCRNIHEETPLMIALREDR 215 79999*****9956*****************98665 PP == domain 5 score: 12.8 bits; conditional E-value: 4.7e-05 Ank_4 4 AaksghlellklLlengadinatdgngetaLhfAas 39 A + ++ell+ L +ga++n +d g taLh+A+ FUN_002289-T1 210 ALREDRQELLEDLPLHGAHPNSRDMAGCTALHIAVG 245 666788899999999*******************96 PP == domain 6 score: 23.7 bits; conditional E-value: 1.6e-08 Ank_4 1 lhaAaksghlellklLlengadinatdgngetaLhfAas 39 lh A+ + +++ ++ ++n ad+n+ d +++taLh A++ FUN_002289-T1 240 LHIAVGRTCVKSVEIMIQNSADVNMKDSSCRTALHVASR 278 799999*******************************86 PP == domain 7 score: 17.6 bits; conditional E-value: 1.4e-06 Ank_4 7 sghlellklLlengadinatdgngetaLh 35 ++++++ k+Ll+n ad+n d++g+ +Lh FUN_002289-T1 285 KSNVKVMKSLLSNNADVNVADNQGRRPLH 313 7899************************* PP == domain 8 score: 0.6 bits; conditional E-value: 0.31 Ank_4 12 llklLlengadinatdgngetaL 34 +l+ Lle++ad+ td + +L FUN_002289-T1 327 ALECLLEHDADPSLTDAIERMPL 349 577799*****999988776666 PP == domain 9 score: 9.2 bits; conditional E-value: 0.00063 Ank_4 11 ellklLlengadinatdgng 30 ++++ L+e g+din++d +g FUN_002289-T1 410 KVIRELVEAGVDINCQDIEG 429 689*************9977 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.0 0.00035 1.3 8 43 .. 32 68 .. 27 69 .. 0.88 2 ! 19.7 0.0 3.3e-07 0.0012 18 53 .. 88 123 .. 82 125 .. 0.94 3 ! 5.4 0.0 0.01 36 26 47 .. 143 164 .. 141 167 .. 0.88 4 ! 14.9 0.2 1.1e-05 0.039 13 56 .] 166 210 .. 161 210 .. 0.89 5 ! 20.4 0.1 1.9e-07 0.00068 7 56 .] 229 276 .. 224 276 .. 0.84 6 ! 6.6 0.0 0.0042 15 20 55 .. 279 314 .. 279 315 .. 0.82 7 ! 7.2 0.2 0.0027 9.9 1 54 [. 294 350 .. 294 351 .. 0.72 8 ? 3.1 0.0 0.053 1.9e+02 35 49 .. 415 429 .. 411 434 .. 0.66 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00035 Ank_5 8 dlnrldgegytpLhvAak.ygaleivrlLlangvdln 43 ++n + +g +L++A+k ++ +v++Ll+ ++d+n FUN_002289-T1 32 NPNFVNSYGLSALCMAVKaFQSPSLVEKLLKMNADPN 68 677779999*********************8888876 PP == domain 2 score: 19.7 bits; conditional E-value: 3.3e-07 Ank_5 18 tpLhvAakygaleivrlLlangvdlnlkdeegltpl 53 pLhvAa+ +++ i ++Ll+ g+d+n+ ++ +tpl FUN_002289-T1 88 SPLHVAAWLRHPGITKVLLDGGADPNTVAFNSSTPL 123 79*****************************9**98 PP == domain 3 score: 5.4 bits; conditional E-value: 0.01 Ank_5 26 ygaleivrlLlangvdlnlkde 47 + al++++lL++ng+d+++ d+ FUN_002289-T1 143 QAALDVMKLLIDNGADVTAVDN 164 6799**************9997 PP == domain 4 score: 14.9 bits; conditional E-value: 1.1e-05 Ank_5 13 dgegytpLhvAakygaleivrlLl.angvdlnlkdeegltpldlA 56 ++g+ Lh+A +g+ iv++Ll + d+n+++ + +tpl +A FUN_002289-T1 166 KTDGTSLLHMATQGGHVLIVNYLLsLRALDVNCRNIHEETPLMIA 210 4567799**********************************9777 PP == domain 5 score: 20.4 bits; conditional E-value: 1.9e-07 Ank_5 7 adlnrldgegytpLhvAakygaleivrlLlangvdlnlkdeegltpldlA 56 + + g+ t+Lh+A+ + + v++++ n +d+n+kd+++ t+l++A FUN_002289-T1 229 PNSRDMAGC--TALHIAVGRTCVKSVEIMIQNSADVNMKDSSCRTALHVA 276 444444445..************************************998 PP == domain 6 score: 6.6 bits; conditional E-value: 0.0042 Ank_5 20 LhvAakygaleivrlLlangvdlnlkdeegltpldl 55 L++ +++ + +++ Ll n++d+n+ d++g pl+l FUN_002289-T1 279 LNNSSSKSNVKVMKSLLSNNADVNVADNQGRRPLHL 314 566778888889999999999999999999877765 PP == domain 7 score: 7.2 bits; conditional E-value: 0.0027 Ank_5 1 LlengpadlnrldgegytpLhvAakyga..leivrlLl..angvdlnlkdeegltpld 54 Ll n ad+n d+ g pLh+ + + l++ l + ++++d+ l+d+ +pl FUN_002289-T1 294 LLSNN-ADVNVADNQGRRPLHLTVIDNKdtLDMTALECllEHDADPSLTDAIERMPLS 350 67776.99999999999****9988665124444444445999999999988887775 PP == domain 8 score: 3.1 bits; conditional E-value: 0.053 Ank_5 35 Llangvdlnlkdeeg 49 L++ gvd+n++d eg FUN_002289-T1 415 LVEAGVDINCQDIEG 429 557777888777776 PP >> Ank_3 Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.076 2.8e+02 8 30 .. 46 68 .. 39 69 .. 0.72 2 ! 10.5 0.0 0.00032 1.2 4 30 .. 88 113 .. 86 114 .. 0.95 3 ? 5.6 0.0 0.013 46 13 30 .. 144 160 .. 140 161 .. 0.84 4 ! 9.5 0.1 0.00067 2.4 4 30 .. 171 197 .. 168 198 .. 0.87 5 ? 3.8 0.0 0.049 1.8e+02 3 21 .. 204 222 .. 202 231 .. 0.75 6 ! 13.8 0.0 2.6e-05 0.095 2 31 .] 236 264 .. 235 264 .. 0.96 7 ! 11.3 0.0 0.00017 0.6 3 31 .] 270 303 .. 270 303 .. 0.93 8 ? 4.6 0.0 0.027 98 2 29 .. 308 338 .. 307 340 .. 0.73 9 ? 2.2 0.0 0.16 5.7e+02 17 31 .] 411 424 .. 406 424 .. 0.89 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.076 Ank_3 8 lAarngrle.ivklLleklgadin 30 +A++ + + +v+ Ll+ ++ad+n FUN_002289-T1 46 MAVKAFQSPsLVEKLLK-MNADPN 68 55555555559******.****99 PP == domain 2 score: 10.5 bits; conditional E-value: 0.00032 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 +pLh+Aa ++ i k+Ll+ gad+n FUN_002289-T1 88 SPLHVAAWLRHPGITKVLLD-GGADPN 113 8*******************.*****9 PP == domain 3 score: 5.6 bits; conditional E-value: 0.013 Ank_3 13 grleivklLleklgadin 30 + l+++klL++ +gad+ FUN_002289-T1 144 AALDVMKLLID-NGADVT 160 6789*******.****85 PP == domain 4 score: 9.5 bits; conditional E-value: 0.00067 Ank_3 4 tpLhlAarngrleivklLleklgadin 30 ++Lh+A g++ iv +Ll + d+n FUN_002289-T1 171 SLLHMATQGGHVLIVNYLLSLRALDVN 197 89*****************98777777 PP == domain 5 score: 3.8 bits; conditional E-value: 0.049 Ank_3 3 ntpLhlAarngrleivklL 21 +tpL++A r +r e+++ L FUN_002289-T1 204 ETPLMIALREDRQELLEDL 222 8********9987777665 PP == domain 6 score: 13.8 bits; conditional E-value: 2.6e-05 Ank_3 2 gntpLhlAarngrleivklLleklgadina 31 g+t+Lh+A+ +++ v+ +++ + ad+n+ FUN_002289-T1 236 GCTALHIAVGRTCVKSVEIMIQ-NSADVNM 264 89************99******.*****95 PP == domain 7 score: 11.3 bits; conditional E-value: 0.00017 Ank_3 3 ntpLhlAarngrl......eivklLleklgadina 31 +t+Lh+A r ++ +++k Ll ++ad+n+ FUN_002289-T1 270 RTALHVASRLNNSssksnvKVMKSLLS-NNADVNV 303 79***********99998889******.*****95 PP == domain 8 score: 4.6 bits; conditional E-value: 0.027 Ank_3 2 gntpLh.lAarngrl...eivklLleklgadi 29 g+ pLh +++ n + +++++Lle + ad+ FUN_002289-T1 308 GRRPLHlTVIDNKDTldmTALECLLE-HDADP 338 88999955555555564445******.99998 PP == domain 9 score: 2.2 bits; conditional E-value: 0.16 Ank_3 17 ivklLleklgadina 31 +++ L+e g+din+ FUN_002289-T1 411 VIRELVE-AGVDINC 424 79*****.9****96 PP >> Ank_KRIT1 KRIT1 ankyrin-repeats domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 4.9 0.0 0.0077 28 41 90 .. 80 124 .. 55 132 .. 0.73 2 ! 12.1 0.0 4.7e-05 0.17 42 101 .. 165 219 .. 153 246 .. 0.70 3 ? 2.7 0.0 0.036 1.3e+02 87 142 .. 238 293 .. 222 300 .. 0.81 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0077 Ank_KRIT1 41 rekvddpes.lvaAakgGheevlqlLlalGkadpdPepvkslkpeystPll 90 r++ + + s l+ Aa+ h ++++Ll+ G+adp+ ++ + stPll FUN_002289-T1 80 RKTEKPSGSpLHVAAWLRHPGITKVLLD-GGADPN-----TVAFNSSTPLL 124 54444444459****************8.667887.....33445677776 PP == domain 2 score: 12.1 bits; conditional E-value: 4.7e-05 Ank_KRIT1 42 ekvddpeslvaAakgGheevlqlLlalGkadpdPepvkslkpeystPllAaiGrenlkvi 101 +k+d + l++A++gGh ++++Ll l d + + +++ +tPl+ a ++ +++ FUN_002289-T1 165 TKTDGTSLLHMATQGGHVLIVNYLLSLRALDVNCRNIHE-----ETPLMIALREDRQELL 219 3444455589999**************999999665554.....5888777766666655 PP == domain 3 score: 2.7 bits; conditional E-value: 0.036 Ank_KRIT1 87 tPllAaiGrenlkvikllldqeefdptrrlkgetyleiarerkgenweeeeklLke 142 t l a+Gr +k ++++++++ ++ +t l +a + ++++ + + k++k+ FUN_002289-T1 238 TALHIAVGRTCVKSVEIMIQNSADVNMKDSSCRTALHVASRLNNSSSKSNVKVMKS 293 667789***********997665445555999999****99999999999999987 PP >> UDPG_MGDP_dh_C UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.6 0.0 0.0038 14 18 38 .. 144 164 .. 142 182 .. 0.89 2 ? 2.7 0.0 0.061 2.2e+02 20 41 .. 288 309 .. 281 335 .. 0.87 3 ? -1.3 0.0 1.1 4e+03 21 37 .. 410 426 .. 407 430 .. 0.88 Alignments for each domain: == domain 1 score: 6.6 bits; conditional E-value: 0.0038 UDPG_MGDP_dh_C 18 paldiieeLkeegaevkvyDP 38 ald+++ L ++ga+v+++D FUN_002289-T1 144 AALDVMKLLIDNGADVTAVDN 164 589****************97 PP == domain 2 score: 2.7 bits; conditional E-value: 0.061 UDPG_MGDP_dh_C 20 ldiieeLkeegaevkvyDPkvk 41 ++++++L++++a+v+v D + + FUN_002289-T1 288 VKVMKSLLSNNADVNVADNQGR 309 799***************8865 PP == domain 3 score: -1.3 bits; conditional E-value: 1.1 UDPG_MGDP_dh_C 21 diieeLkeegaevkvyD 37 ++i+eL e+g++++ D FUN_002289-T1 410 KVIRELVEAGVDINCQD 426 79**********99888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (436 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 620 (0.0242709); expected 510.9 (0.02) Passed bias filter: 528 (0.0206694); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 4227.59 // Query: FUN_002290-T1 [L=317] Description: FUN_002290 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.8e-05 24.8 0.0 7.1e-05 23.5 0.0 1.7 1 Ank_4 Ankyrin repeats (many copies) 5.3e-05 23.8 0.0 0.84 10.6 0.0 2.9 2 Ank Ankyrin repeat 0.0034 18.4 0.0 0.0066 17.5 0.0 1.5 1 Ank_2 Ankyrin repeats (3 copies) 0.0095 16.8 0.0 0.022 15.6 0.0 1.6 1 Ank_5 Ankyrin repeats (many copies) Domain annotation for each model (and alignments): >> Ank_4 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 1.1e-08 7.1e-05 13 49 .. 26 62 .. 17 63 .. 0.94 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 1.1e-08 Ank_4 13 lklLlengadinatdgngetaLhfAasngnlevlklL 49 + Ll+ gad na+d +g+t+ h+Aa +++ + l++L FUN_002290-T1 26 TRVLLDAGADRNARDIDGNTPAHIAAEGEDADQLRML 62 689*****************************99998 PP >> Ank Ankyrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.6 0.0 0.00013 0.84 4 32 .. 4 40 .. 2 41 .. 0.85 2 ! 10.1 0.0 0.00019 1.2 1 21 [. 42 62 .. 42 72 .. 0.86 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00013 Ank 4 TPLHlAa.ragh.......levvklLLkhGAdvnard 32 T+LH + r+g+ + + LL++GAd nard FUN_002290-T1 4 TCLHHTVgRKGRtsshlkfSDFTRVLLDAGADRNARD 40 999999996677777788899******88*******9 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00019 Ank 1 dGnTPLHlAaraghlevvklL 21 dGnTP H+Aa+ + + +++L FUN_002290-T1 42 DGNTPAHIAAEGEDADQLRML 62 8*********87778887777 PP >> Ank_2 Ankyrin repeats (3 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 1e-06 0.0066 11 62 .. 24 77 .. 4 84 .. 0.72 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1e-06 Ank_2 11 elvklLl.egadanlqdkngetaLhlAaknghleivklLlehgadvn..dnngrt 62 ++ + Ll gad n +d +g+t+ h+Aa+ ++ ++ L+++ + ++ + ng+t FUN_002290-T1 24 DFTRVLLdAGADRNARDIDGNTPAHIAAEGEDADQLRMLASETW-QDcpNLNGET 77 56677777888888777788888888888887777888887643.2323355655 PP >> Ank_5 Ankyrin repeats (many copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 3.5e-06 0.022 30 56 .] 24 50 .. 23 62 .. 0.90 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 3.5e-06 Ank_5 30 eivrlLlangvdlnlkdeegltpldlA 56 ++ r+Ll+ g+d n++d +g+tp ++A FUN_002290-T1 24 DFTRVLLDAGADRNARDIDGNTPAHIA 50 678999999999999999999999998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 709 (0.0277549); expected 510.9 (0.02) Passed bias filter: 615 (0.0240752); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3076.08 // Query: FUN_002291-T1 [L=184] Description: FUN_002291 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-05 24.7 0.0 5.5e-05 23.8 0.0 1.4 1 Mab-21 Mab-21 protein nucleotidyltransferase domain Domain annotation for each model (and alignments): >> Mab-21 Mab-21 protein nucleotidyltransferase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 2.1e-09 5.5e-05 3 139 .. 6 149 .. 4 167 .. 0.72 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 2.1e-09 Mab-21 3 enlkvlsPdeFdlvlkLklpeneeiivkedpggpgyvelkltrsg..esndnsrkellsqwleeaegylsaaKvlsrfqslvekalkklekeievn 96 e++k +PdeFd++ +L+ + + +++p y+ l +++ s d++ ke ++++l + ++ ls++K++ f l +a l+++++ + FUN_002291-T1 6 EETKLWKPDEFDFMMELT--------QLKGHSRPEYAGLSRSSNTtvISLDDEMKEMWREFL-K-DDCLSPEKLRDYFVLLTWRAGFSLQRQKY-K 90 789999************........33444559999999888334788888999*******.6.89************999999988766555.3 PP Mab-21 97 detlklsykrk.......gpavt.....vaietseeq..............ysVdlvpaielkasWpks 139 + +ls ++ p v+ v ++Vdl++++++++ Wp FUN_002291-T1 91 NLSFNLS--QQsggtgssHPLVRmssvgV-------LlhvqwhgydytsldIDVDLTLSVPFSD-WPVL 149 3333333..33668876633333333222.......133333346688899*************.9965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (184 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 513 (0.0200822); expected 510.9 (0.02) Passed bias filter: 484 (0.018947); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.33s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1870.10 // Query: FUN_002292-T1 [L=178] Description: FUN_002292 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (178 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 407 (0.0159327); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1801.91 // Query: FUN_002293-T1 [L=124] Description: FUN_002293 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-18 65.9 0.4 5.8e-18 65.6 0.4 1.2 1 Histone Core histone H2A/H2B/H3/H4 domain 2e-08 34.5 0.0 2.5e-08 34.1 0.0 1.2 1 Histone_ABTB Histone domain in ABTB family protein 0.0034 18.1 0.0 0.0069 17.1 0.0 1.5 1 CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) a ------ inclusion threshold ------ 0.051 14.1 0.3 0.06 13.8 0.3 1.2 1 YscO-like YscO-like protein 0.25 12.4 0.0 0.48 11.5 0.0 1.4 1 TFIID_20kDa Transcription initiation factor TFIID subunit Domain annotation for each model (and alignments): >> Histone Core histone H2A/H2B/H3/H4 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.6 0.4 1.1e-21 5.8e-18 7 88 .] 22 99 .. 16 99 .. 0.94 Alignments for each domain: == domain 1 score: 65.6 bits; conditional E-value: 1.1e-21 Histone 7 keirkyqkstdlliqklpfaRvvrevvkstkedlrisaeavvalqeavedllvelfeeAnllakhaKRvTltpkDiqlAvrl 88 e k+++ +++++++++ ++v+++v++ d +is++a+ +++++v+d++++++ e+++l+ ++K+ T+ +++iq+A+rl FUN_002293-T1 22 AETAKRRRGKRKESYAIYKYKVLKQVHP----DTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 57788999999*****************....************************************************97 PP >> Histone_ABTB Histone domain in ABTB family protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.1 0.0 4.9e-12 2.5e-08 23 91 .. 53 123 .. 37 124 .] 0.86 Alignments for each domain: == domain 1 score: 34.1 bits; conditional E-value: 4.9e-12 Histone_ABTB 23 vsvevvkrlsallqraLvriareaqRLskllakct..keevksavklvlseslaesCikaavkAvslyals 91 +s +++ + ++++ ria e +RLs ++k t ++e+++a++l+l+ +la++ ++ ++kAv+ y+ s FUN_002293-T1 53 ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATisSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSS 123 7888888899999999************99998763378****************************9865 PP >> CBFD_NFYB_HMF Histone-like transcription factor (CBF/NF-Y) and archaeal histone # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.3e-06 0.0069 10 65 .] 42 97 .. 41 97 .. 0.95 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.3e-06 CBFD_NFYB_HMF 10 rImksd.pdarkiskdAkeliaecveefieevaseAaeickkekrKTikaehiklAv 65 +++k+ pd++ is+ A +++ +v + e++a e++++ k+ Ti++ i+ A+ FUN_002293-T1 42 KVLKQVhPDTG-ISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAI 97 899***88888.*****************************************9996 PP >> YscO-like YscO-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.3 1.2e-05 0.06 38 113 .. 25 99 .. 6 119 .. 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.2e-05 YscO-like 38 lakleaerdkvlkhkkaKlqqlrd.eldkGttsdkikkmkeyikvvkeelkqeekkvedqkekVevAkkklEearee 113 ++++ +r + + K + l++ + d G +s+++ +m+++++ + e++++e ++ ++k ++ ++++ a FUN_002293-T1 25 AKRRRGKRKESYAIY--KYKVLKQvHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRL 99 333333344444444..44445542569******************************************9988655 PP >> TFIID_20kDa Transcription initiation factor TFIID subunit A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.4e-05 0.48 8 60 .. 43 95 .. 41 99 .. 0.93 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.4e-05 TFIID_20kDa 8 LvqqidseekLdedvedlLleiaddFvesvtkkacklakhRksdklevrDiql 60 ++q+ +++ + + ++ ++d e + ++++l + k ++++r iq FUN_002293-T1 43 VLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQT 95 5899***********************************************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (124 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 809 (0.0316696); expected 510.9 (0.02) Passed bias filter: 480 (0.0187904); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1256.98 // Query: FUN_002294-T1 [L=99] Description: FUN_002294 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (99 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 500 (0.0195733); expected 510.9 (0.02) Passed bias filter: 374 (0.0146408); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.39s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1010.99 // Query: FUN_002295-T1 [L=142] Description: FUN_002295 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.036 14.6 0.6 0.053 14.1 0.6 1.2 1 CENP-F_leu_zip Leucine-rich repeats of kinetochore protein C 0.045 14.1 0.3 0.061 13.7 0.3 1.3 1 TRIM_CC TRIM protein coiled-coil region 0.051 12.9 0.1 0.052 12.8 0.1 1.1 1 ECM29_N Proteasome component ECM29, N-terminal 0.066 13.4 0.5 0.086 13.0 0.5 1.2 1 Plectin_PPL Periplakin-like, plectin repeat 0.11 13.4 0.0 0.16 12.9 0.0 1.3 1 DUF5905 Family of unknown function (DUF5905) Domain annotation for each model (and alignments): >> CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.6 1e-05 0.053 67 103 .. 2 38 .. 1 47 [. 0.87 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 1e-05 CENP-F_leu_zip 67 elrqleldLvtlrsekeeLtkeLqkkqervseLesln 103 ++ qle dL ++++ ke+L++eL+k ++ ++ L+ + FUN_002295-T1 2 TTDQLEKDLPEVSRMKENLESELNKAKDHIQFLKGKK 38 5789**************************9998765 PP >> TRIM_CC TRIM protein coiled-coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.3 1.2e-05 0.061 66 98 .. 3 36 .. 1 71 [. 0.86 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.2e-05 TRIM_CC 66 leeLeqeiaeLkkrdaeleq.LsqteDhihFLqe 98 ++Le+++ e + +++le+ L + +Dhi+FL+ FUN_002295-T1 3 TDQLEKDLPEVSRMKENLESeLNKAKDHIQFLKG 36 579***************976***********96 PP >> ECM29_N Proteasome component ECM29, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 1e-05 0.052 322 376 .. 58 117 .. 13 132 .. 0.74 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1e-05 ECM29_N 322 ssgless.KLrslalqFinwvarhgs....ekelkkiapsllsglrkliesqgwpkpsek 376 s+g + + + ++ lqF++++ ++g+ +++++++ap l+++++k+i ++g +k +++ FUN_002295-T1 58 STGSSFEeLVAQFQLQFFRHYNNKGPplydPNDMEAFAPALFTQILKSILNNGMSKDRQD 117 444222246778899999999999996665666*****************9999887322 PP >> Plectin_PPL Periplakin-like, plectin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.5 1.7e-05 0.086 8 58 .. 4 54 .. 1 72 [. 0.87 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 1.7e-05 Plectin_PPL 8 erlrkeleeerrkrsklekEieqlqkklatlesekkkveeklvtkevvkle 58 ++l+k l e +r +++le+E+++++ ++ l+ +k +++ ++ ++vk FUN_002295-T1 4 DQLEKDLPEVSRMKENLESELNKAKDHIQFLKGKKDYITKVSLIVQIVKTS 54 679999999************************999999988888888865 PP >> DUF5905 Family of unknown function (DUF5905) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 3.1e-05 0.16 20 55 .. 22 55 .. 5 73 .. 0.74 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 3.1e-05 DUF5905 20 reekvsllllayllGketeeYiekleraldalekvr 55 +e + + ++++l Gk ++Yi+k++ +++ ++ r FUN_002295-T1 22 SELNKAKDHIQFLKGK--KDYITKVSLIVQIVKTSR 55 566778899*******..9*********99988443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (142 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1281 (0.0501468); expected 510.9 (0.02) Passed bias filter: 890 (0.0348405); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 1417.22 // Query: FUN_002296-T1 [L=129] Description: FUN_002296 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.22 11.1 0.0 0.23 11.1 0.0 1.1 1 DUF1464 Protein of unknown function (DUF1464) Domain annotation for each model (and alignments): >> DUF1464 Protein of unknown function (DUF1464) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 9e-06 0.23 7 67 .. 7 66 .. 5 109 .. 0.81 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 9e-06 DUF1464 7 ksydvvavdelgkvvlekeiptdevekdpsvlvkaieearadivalpSGyGlPlkkisela 67 + ++++ +d+ +v k++pt++++ ++ ++ + + +++i a+p +Pl++ +++ FUN_002296-T1 7 NCFAILLIDDYHNVH-AKKVPTKLITSTATHMASCLLDIHPTIPAVPHPQQTPLHRPVKIT 66 5799******77765.678*****************************9999999987776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (129 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1079 (0.0422392); expected 510.9 (0.02) Passed bias filter: 880 (0.034449); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1324.46 // Query: FUN_002297-T1 [L=248] Description: FUN_002297 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (248 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1142 (0.0447054); expected 510.9 (0.02) Passed bias filter: 692 (0.0270894); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.33u 0.37s 00:00:00.70 Elapsed: 00:00:00.42 # Mc/sec: 2384.31 // Query: FUN_002298-T1 [L=62] Description: FUN_002298 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (62 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 541 (0.0211783); expected 510.9 (0.02) Passed bias filter: 434 (0.0169896); expected 510.9 (0.02) Passed Vit filter: 18 (0.000704639); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.36s 00:00:00.60 Elapsed: 00:00:00.39 # Mc/sec: 646.39 // Query: FUN_002302-T1 [L=132] Description: FUN_002302 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0012 19.5 6.3 2.2 8.8 0.3 3.9 4 bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal 0.0021 18.7 3.5 7 7.4 0.1 4.1 4 DUF7348 Domain of unknown function (DUF7348) ------ inclusion threshold ------ 0.02 13.7 0.0 0.43 9.3 0.0 2.0 2 Gp58 gp58-like protein 0.055 14.4 14.1 0.32 11.9 0.7 3.8 4 DUF2554 Protein of unknown function (DUF2554) 0.19 12.7 0.1 8.3 7.4 0.0 2.8 3 Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransfer 0.37 11.3 6.2 2.2 8.9 0.7 3.1 3 DUF4287 Domain of unknown function (DUF4287) 1.4 9.1 8.2 5.3 7.1 0.5 3.2 3 DNA_ligase_A_M ATP dependent DNA ligase domain 1.4 8.6 9.4 0.55 9.9 1.3 3.0 5 DUF632 Protein of unknown function (DUF632) 5.5 7.9 9.2 5.4 8.0 0.2 3.5 4 DUF3761 Protein of unknown function (DUF3761) Domain annotation for each model (and alignments): >> bCoV_NSP3_N Betacoronavirus replicase NSP3, N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.1 0.0 0.0028 7.8 75 108 .. 13 46 .. 6 50 .. 0.82 2 ? 3.3 0.1 0.039 1.1e+02 90 108 .. 50 68 .. 47 71 .. 0.85 3 ! 8.8 0.3 0.00078 2.2 74 108 .. 67 101 .. 65 111 .. 0.85 4 ? 3.8 0.1 0.028 79 74 102 .. 100 128 .. 98 131 .. 0.86 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0028 bCoV_NSP3_N 75 ddyqglplefgasaetvrveeeeeedwlddtteq 108 + +g+ + ++ vrv+ e++ dw+ d e+ FUN_002302-T1 13 NKRDGVRVYHKRKSDGVRVNHEKKSDWVRDDHEK 46 5556777777788999************998775 PP == domain 2 score: 3.3 bits; conditional E-value: 0.039 bCoV_NSP3_N 90 tvrveeeeeedwlddtteq 108 +rv e++ dwl d e+ FUN_002302-T1 50 GLRVHHEKKSDWLRDDHEK 68 589**********998775 PP == domain 3 score: 8.8 bits; conditional E-value: 0.00078 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwlddtteq 108 e +gl + ++ vrv+ e+ dw+ d e+ FUN_002302-T1 67 EKKCDGLRVHHEKKSDGVRVDHEKTSDWVRDDHEK 101 55678999999999**************9887765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.028 bCoV_NSP3_N 74 eddyqglplefgasaetvrveeeeeedwl 102 e +gl ++ + vrv+ e++e w FUN_002302-T1 100 EKKSDGLSVDHEKKSHGVRVDHEKKERWD 128 5567899999999**************95 PP >> DUF7348 Domain of unknown function (DUF7348) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.23 6.6e+02 20 33 .. 16 31 .. 3 45 .. 0.59 2 ? 5.5 0.0 0.01 29 18 28 .. 47 57 .. 33 66 .. 0.77 3 ! 7.4 0.1 0.0025 7 18 37 .. 69 90 .. 55 101 .. 0.70 4 ? 4.1 0.1 0.028 79 19 45 .. 103 129 .. 93 132 .] 0.71 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.23 DUF7348 20 DGLrv..erdddgYrl 33 DG rv +r++dg r+ FUN_002302-T1 16 DGVRVyhKRKSDGVRV 31 5555533335555554 PP == domain 2 score: 5.5 bits; conditional E-value: 0.01 DUF7348 18 dfDGLrverdd 28 +fDGLrv++++ FUN_002302-T1 47 KFDGLRVHHEK 57 7******8755 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0025 DUF7348 18 dfDGLrver..dddgYrletpd 37 ++DGLrv++ ++dg r++ ++ FUN_002302-T1 69 KCDGLRVHHekKSDGVRVDHEK 90 79*****664588889887433 PP == domain 4 score: 4.1 bits; conditional E-value: 0.028 DUF7348 19 fDGLrverdddgYrletpdeertglse 45 DGL+v+++++ +++ +e+++ +e FUN_002302-T1 103 SDGLSVDHEKKSHGVRVDHEKKERWDE 129 59****997776666655666665555 PP >> Gp58 gp58-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.0072 20 218 250 .. 4 36 .. 2 41 .. 0.89 2 ? 9.3 0.0 0.00015 0.43 154 250 .. 28 124 .. 27 126 .. 0.85 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.0072 Gp58 218 ssGtteayeskLddlraeftrsnqGmrvelesk 250 s+G ye+k d++r + r + G+rv+ e k FUN_002302-T1 4 SDGVRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 6777888*********************99977 PP == domain 2 score: 9.3 bits; conditional E-value: 0.00015 Gp58 154 GirreyqdadrqlsssyqagieGlkatlksdkiGlqaeiqasaqgLsqrydneirkLsakitttssGtteayeskLddlraeftrsnqGmrveles 249 G+r ++++ + +++ +Gl+ ++ + l+ + + gL +++++ ++ +ts+ + +e+k d+l ++ + + G+rv+ e FUN_002302-T1 28 GVRVNHEKKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKCDGLRVHHEKKSDGVRVDHEKTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEK 123 666666666666777888999999998888888899999999999999999999999999999999999999999999999999999999999887 PP Gp58 250 k 250 k FUN_002302-T1 124 K 124 6 PP >> DUF2554 Protein of unknown function (DUF2554) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.5 1.4e+03 45 64 .. 4 23 .. 2 29 .. 0.77 2 ? 10.1 1.2 0.00042 1.2 35 64 .. 27 56 .. 11 60 .. 0.82 3 ? 11.9 0.7 0.00011 0.32 39 64 .. 53 78 .. 51 85 .. 0.90 4 ? 3.7 1.7 0.042 1.2e+02 40 60 .. 98 118 .. 79 131 .. 0.55 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.5 DUF2554 45 sdelravaeesaeGlrehfy 64 sd +r e+ +G+r +++ FUN_002302-T1 4 SDGVRVHYENKRDGVRVYHK 23 78888888888889888775 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00042 DUF2554 35 vdhqlrheadsdelravaeesaeGlrehfy 64 + ++ he sd +r e+ +Glr h+ FUN_002302-T1 27 DGVRVNHEKKSDWVRDDHEKKFDGLRVHHE 56 456788**********************97 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00011 DUF2554 39 lrheadsdelravaeesaeGlrehfy 64 + he sd lr e+ +Glr h+ FUN_002302-T1 53 VHHEKKSDWLRDDHEKKCDGLRVHHE 78 67**********************97 PP == domain 4 score: 3.7 bits; conditional E-value: 0.042 DUF2554 40 rheadsdelravaeesaeGlr 60 he sd l e+ + G+r FUN_002302-T1 98 DHEKKSDGLSVDHEKKSHGVR 118 255555555555555555555 PP >> Methyltr_RsmF_N N-terminal domain of 16S rRNA methyltransferase RsmF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.4 0.0 0.0029 8.3 22 69 .. 19 66 .. 10 78 .. 0.70 2 ? 1.9 0.0 0.16 4.4e+02 23 39 .. 75 91 .. 56 108 .. 0.62 3 ? 1.1 0.0 0.28 8e+02 25 44 .. 110 127 .. 88 132 .] 0.70 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0029 Methyltr_RsmF_N 22 aaleeplrkglRvNtlkiskeeleklaa..efelepvpwceeGfyleeee 69 + +++ ++ g+RvN+ k k+++ + + +f+ +v + ++ +l++++ FUN_002302-T1 19 RVYHKRKSDGVRVNHEK--KSDWVRDDHekKFDGLRVHHEKKSDWLRDDH 66 67889999*********..3343333222477788888887777777664 PP == domain 2 score: 1.9 bits; conditional E-value: 0.16 Methyltr_RsmF_N 23 aleeplrkglRvNtlki 39 +e+++ g+Rv + k+ FUN_002302-T1 75 VHHEKKSDGVRVDHEKT 91 33455566666666663 PP == domain 3 score: 1.1 bits; conditional E-value: 0.28 Methyltr_RsmF_N 25 eeplrkglRvNtlkiskeel 44 +e++++g+Rv + k ke++ FUN_002302-T1 110 HEKKSHGVRVDHEK--KERW 127 67788999999999..5555 PP >> DUF4287 Domain of unknown function (DUF4287) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.035 1e+02 28 45 .. 28 45 .. 18 46 .. 0.80 2 ? 8.9 0.7 0.00077 2.2 19 45 .. 38 67 .. 37 68 .. 0.85 3 ? 2.8 0.2 0.062 1.8e+02 30 45 .. 82 100 .. 73 101 .. 0.78 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.035 DUF4287 28 gllvkhgervawLkeehg 45 g v+h++ +w +++h+ FUN_002302-T1 28 GVRVNHEKKSDWVRDDHE 45 34489************6 PP == domain 2 score: 8.9 bits; conditional E-value: 0.00077 DUF4287 19 eWlalveeggll...vkhgervawLkeehg 45 +W++ +e++++ v h++ +wL+++h+ FUN_002302-T1 38 DWVRDDHEKKFDglrVHHEKKSDWLRDDHE 67 6777777888888889*************6 PP == domain 3 score: 2.8 bits; conditional E-value: 0.062 DUF4287 30 l...vkhgervawLkeehg 45 + v h++ +w +++h+ FUN_002302-T1 82 DgvrVDHEKTSDWVRDDHE 100 344489************6 PP >> DNA_ligase_A_M ATP dependent DNA ligase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 0.5 0.0019 5.3 20 43 .. 7 30 .. 1 43 [. 0.78 2 ? 1.2 0.1 0.13 3.6e+02 25 40 .. 45 60 .. 33 63 .. 0.83 3 ? 4.2 0.2 0.014 41 16 36 .. 69 89 .. 62 97 .. 0.58 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.0019 DNA_ligase_A_M 20 kafivEiKyDGeRaqvhkegdevk 43 +++E K DG+R+ ++++d v+ FUN_002302-T1 7 VRVHYENKRDGVRVYHKRKSDGVR 30 456789999999998888888776 PP == domain 2 score: 1.2 bits; conditional E-value: 0.13 DNA_ligase_A_M 25 EiKyDGeRaqvhkegd 40 E K+DG R+ +k++d FUN_002302-T1 45 EKKFDGLRVHHEKKSD 60 89******99887665 PP == domain 3 score: 4.2 bits; conditional E-value: 0.014 DNA_ligase_A_M 16 klegkafivEiKyDGeRaqvh 36 k++g ++ E K DG+R+ + FUN_002302-T1 69 KCDGLRVHHEKKSDGVRVDHE 89 344444555666666666555 PP >> DUF632 Protein of unknown function (DUF632) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.17 4.9e+02 113 142 .. 7 36 .. 3 44 .. 0.56 2 ? 1.8 0.3 0.058 1.6e+02 113 138 .. 29 54 .. 23 59 .. 0.52 3 ? 4.0 0.6 0.013 36 111 136 .. 38 63 .. 32 76 .. 0.56 4 ? 9.9 1.3 0.00019 0.55 108 142 .. 57 91 .. 53 101 .. 0.88 5 ? 2.2 0.5 0.044 1.2e+02 108 142 .. 90 124 .. 86 130 .. 0.81 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.17 DUF632 113 lrieyekkckqLrkleekgaeaskidktra 142 +r+ ye k r +++ + +++ ++ FUN_002302-T1 7 VRVHYENKRDGVRVYHKRKSDGVRVNHEKK 36 555555555555555555555555544443 PP == domain 2 score: 1.8 bits; conditional E-value: 0.058 DUF632 113 lrieyekkckqLrkleekgaeaskid 138 +r+++ekk+ r+ ek+ + ++ FUN_002302-T1 29 VRVNHEKKSDWVRDDHEKKFDGLRVH 54 56666666665555555544443333 PP == domain 3 score: 4.0 bits; conditional E-value: 0.013 DUF632 111 eklrieyekkckqLrkleekgaeask 136 + +r ++ekk Lr + ek+ ++ + FUN_002302-T1 38 DWVRDDHEKKFDGLRVHHEKKSDWLR 63 55556666666666655555555433 PP == domain 4 score: 9.9 bits; conditional E-value: 0.00019 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ lr ++ekkc Lr + ek+ + ++d ++ FUN_002302-T1 57 KKSDWLRDDHEKKCDGLRVHHEKKSDGVRVDHEKT 91 789999*********************99997765 PP == domain 5 score: 2.2 bits; conditional E-value: 0.044 DUF632 108 KaeeklrieyekkckqLrkleekgaeaskidktra 142 K+++ +r ++ekk+ L ek+ + ++d ++ FUN_002302-T1 90 KTSDWVRDDHEKKSDGLSVDHEKKSHGVRVDHEKK 124 67788888899999999888888888888887765 PP >> DUF3761 Protein of unknown function (DUF3761) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 0.59 1.7e+03 36 45 .. 5 14 .. 2 29 .. 0.59 2 ? 8.0 0.2 0.0019 5.4 22 57 .. 35 70 .. 25 73 .. 0.85 3 ? 3.9 0.2 0.035 1e+02 23 48 .. 58 83 .. 55 88 .. 0.82 4 ? 2.3 0.3 0.11 3.1e+02 23 47 .. 91 115 .. 83 124 .. 0.80 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.59 DUF3761 36 DGqrvhkPer 45 DG rvh ++ FUN_002302-T1 5 DGVRVHYENK 14 6666665443 PP == domain 2 score: 8.0 bits; conditional E-value: 0.0019 DUF3761 22 eesdLttedsyvnrDGqrvhkPeraksapagatarC 57 ++sd + +d+ DG rvh+ +++ +++ +C FUN_002302-T1 35 KKSDWVRDDHEKKFDGLRVHHEKKSDWLRDDHEKKC 70 47999****************999988888888877 PP == domain 3 score: 3.9 bits; conditional E-value: 0.035 DUF3761 23 esdLttedsyvnrDGqrvhkPeraks 48 +sd +d+ DG rvh+ +++ FUN_002302-T1 58 KSDWLRDDHEKKCDGLRVHHEKKSDG 83 688889999999*******9887765 PP == domain 4 score: 2.3 bits; conditional E-value: 0.11 DUF3761 23 esdLttedsyvnrDGqrvhkPerak 47 sd + +d+ +DG v + ++++ FUN_002302-T1 91 TSDWVRDDHEKKSDGLSVDHEKKSH 115 699999**********997766655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (132 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 930 (0.0364063); expected 510.9 (0.02) Passed bias filter: 365 (0.0142885); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1318.21 // Query: FUN_002303-T1 [L=447] Description: FUN_002303 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-06 26.9 0.0 1e-05 25.8 0.0 1.5 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.17 12.7 0.0 6.9 7.6 0.0 2.5 2 Phage_int_SAM_4 Phage integrase, N-terminal SAM-like domain 0.22 12.3 3.0 0.69 10.7 0.1 2.9 3 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.8 0.0 1.2e-09 1e-05 56 142 .. 188 282 .. 176 313 .. 0.83 Alignments for each domain: == domain 1 score: 25.8 bits; conditional E-value: 1.2e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002303-T1 188 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 280 455444445555679*****9999********9999999999******************************995555.6************97 PP Phage_integrase 141 le 142 + FUN_002303-T1 281 YS 282 65 PP >> Phage_int_SAM_4 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.00081 6.9 46 73 .. 25 52 .. 15 61 .. 0.90 2 ? 2.2 0.0 0.038 3.2e+02 27 71 .. 214 258 .. 190 260 .. 0.84 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.00081 Phage_int_SAM_4 46 ieaflsyLanernvsastqkqalnalsf 73 +e++l +L+ +r +s +t+ ++ ++l++ FUN_002303-T1 25 LESYLDHLKDHRGLSSATIANHASSLVY 52 589*******************999986 PP == domain 2 score: 2.2 bits; conditional E-value: 0.038 Phage_int_SAM_4 27 krfirflkkkhpeelteaeieaflsyLanernvsastqkqalnal 71 + f +++++ +pe + +e ++fl an + +s s+++ +l++l FUN_002303-T1 214 SFFRKYVQEFRPELSSAQEKNDFLFVNANGQPYSGSSFSKHLKNL 258 45666777789999**************9999*****99999887 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.1 8.1e-05 0.69 1 32 [. 25 56 .. 25 85 .. 0.86 2 ? -2.0 0.0 0.76 6.5e+03 46 67 .. 94 116 .. 71 121 .. 0.45 3 ? 0.2 0.4 0.16 1.3e+03 29 69 .. 276 313 .. 264 324 .. 0.71 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 8.1e-05 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_002303-T1 25 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 56 689*******************9998665555 PP == domain 2 score: -2.0 bits; conditional E-value: 0.76 Phage_int_SAM_1 46 sdvraflaelkaeg..lsasslar 67 +d+ a ++ + + l a+sl+r FUN_002303-T1 94 EDLKALNRWVDW-DevLEATSLQR 116 233222222222.12466666666 PP == domain 3 score: 0.2 bits; conditional E-value: 0.16 Phage_int_SAM_1 29 flkflseegesleqittsdvraflaelkaeglsasslarrl 69 fl+++ + ++ +++ ++++a l++++++ ++s+ rr FUN_002303-T1 276 FLTWAYS-QSECTDSMKDSLAAALRHSREQ--AQSTYDRRT 313 4444444.7788888888889999998884..566666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (447 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 794 (0.0310824); expected 510.9 (0.02) Passed bias filter: 573 (0.022431); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4326.49 // Query: FUN_002304-T1 [L=507] Description: FUN_002304 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002304-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002304-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002304-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002304-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.40s 00:00:00.77 Elapsed: 00:00:00.41 # Mc/sec: 5004.30 // Query: FUN_002305-T1 [L=702] Description: FUN_002305 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.12 13.3 0.0 1.4 9.9 0.0 2.4 2 DUF1214 Protein of unknown function (DUF1214) 0.54 10.4 7.2 0.055 13.6 1.9 2.0 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter 0.68 10.7 3.1 1.2 10.0 0.1 2.9 2 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 3.5e-09 2.2e-05 56 142 .. 443 537 .. 432 568 .. 0.84 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.5e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002305-T1 443 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 535 455444445555679*****9999********9999999999******************************995555.6************96 PP Phage_integrase 141 le 142 + FUN_002305-T1 536 YS 537 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.22 1.4e+03 48 88 .. 113 153 .. 103 157 .. 0.74 2 ? 9.9 0.0 0.00022 1.4 57 108 .. 425 474 .. 406 477 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.22 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_002305-T1 113 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 153 556777778666666767889999**********9985544 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00022 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_002305-T1 425 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 474 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 1.9 8.6e-06 0.055 83 123 .. 72 112 .. 24 123 .. 0.79 2 ? -3.5 0.0 1.6 1e+04 24 42 .. 547 565 .. 534 594 .. 0.52 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8.6e-06 MVD-like_N 83 kvkveSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002305-T1 72 AGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 5556899999********************99988766554 PP == domain 2 score: -3.5 bits; conditional E-value: 1.6 MVD-like_N 24 sSlSltldelytkttvefs 42 +Sl +l++ + + + +++ FUN_002305-T1 547 DSLAAALRHSREQAQSTYD 565 3444444433322222222 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.1 0.00019 1.2 1 32 [. 280 311 .. 280 343 .. 0.87 2 ? -0.8 0.5 0.44 2.8e+03 29 69 .. 531 568 .. 520 578 .. 0.71 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_002305-T1 280 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 311 689*******************9998665555 PP == domain 2 score: -0.8 bits; conditional E-value: 0.44 Phage_int_SAM_1 29 flkflseegesleqittsdvraflaelkaeglsasslarrl 69 fl+++ + ++ +++ ++++a l++++++ ++s+ rr FUN_002305-T1 531 FLTWAYS-QSECTDSMKDSLAAALRHSREQ--AQSTYDRRT 568 4444444.7788888888889999998884..567766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (702 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6713.88 // Query: FUN_002306-T1 [L=507] Description: FUN_002306 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002306-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002306-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002306-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002306-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 5145.22 // Query: FUN_002307-T1 [L=374] Description: FUN_002307 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.021 15.0 1.9 0.021 15.0 1.9 1.8 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal Domain annotation for each model (and alignments): >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 1.9 8.4e-07 0.021 81 123 .. 70 112 .. 23 123 .. 0.78 2 ? -1.7 0.2 0.11 2.9e+03 95 110 .. 133 144 .. 114 171 .. 0.57 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 8.4e-07 MVD-like_N 81 elkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 + +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002307-T1 70 DDAGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 555567899999********************99988766554 PP == domain 2 score: -1.7 bits; conditional E-value: 0.11 MVD-like_N 95 aaglASSasgfAalal 110 aa A Sas + + FUN_002307-T1 133 AASTAASAS----IYV 144 333333333....333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (374 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 656 (0.0256802); expected 510.9 (0.02) Passed bias filter: 409 (0.016011); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.33u 0.36s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 3693.16 // Query: FUN_002308-T1 [L=507] Description: FUN_002308 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002308-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002308-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002308-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002308-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.39s 00:00:00.78 Elapsed: 00:00:00.43 # Mc/sec: 4768.58 // Query: FUN_002309-T1 [L=702] Description: FUN_002309 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.12 13.3 0.0 1.4 9.9 0.0 2.4 2 DUF1214 Protein of unknown function (DUF1214) 0.54 10.4 7.2 0.055 13.6 1.9 2.0 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter 0.68 10.7 3.1 1.2 10.0 0.1 2.9 2 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 3.5e-09 2.2e-05 56 142 .. 443 537 .. 432 568 .. 0.84 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.5e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002309-T1 443 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 535 455444445555679*****9999********9999999999******************************995555.6************96 PP Phage_integrase 141 le 142 + FUN_002309-T1 536 YS 537 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.22 1.4e+03 48 88 .. 113 153 .. 103 157 .. 0.74 2 ? 9.9 0.0 0.00022 1.4 57 108 .. 425 474 .. 406 477 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.22 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_002309-T1 113 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 153 556777778666666767889999**********9985544 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00022 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_002309-T1 425 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 474 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 1.9 8.6e-06 0.055 83 123 .. 72 112 .. 24 123 .. 0.79 2 ? -3.5 0.0 1.6 1e+04 24 42 .. 547 565 .. 534 594 .. 0.52 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8.6e-06 MVD-like_N 83 kvkveSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002309-T1 72 AGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 5556899999********************99988766554 PP == domain 2 score: -3.5 bits; conditional E-value: 1.6 MVD-like_N 24 sSlSltldelytkttvefs 42 +Sl +l++ + + + +++ FUN_002309-T1 547 DSLAAALRHSREQAQSTYD 565 3444444433322222222 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.1 0.00019 1.2 1 32 [. 280 311 .. 280 343 .. 0.87 2 ? -0.8 0.5 0.44 2.8e+03 29 69 .. 531 568 .. 520 578 .. 0.71 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_002309-T1 280 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 311 689*******************9998665555 PP == domain 2 score: -0.8 bits; conditional E-value: 0.44 Phage_int_SAM_1 29 flkflseegesleqittsdvraflaelkaeglsasslarrl 69 fl+++ + ++ +++ ++++a l++++++ ++s+ rr FUN_002309-T1 531 FLTWAYS-QSECTDSMKDSLAAALRHSREQ--AQSTYDRRT 568 4444444.7788888888889999998884..567766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (702 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.38u 0.42s 00:00:00.80 Elapsed: 00:00:00.42 # Mc/sec: 6710.03 // Query: FUN_002310-T1 [L=507] Description: FUN_002310 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002310-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002310-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002310-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002310-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 4858.52 // Query: FUN_002311-T1 [L=702] Description: FUN_002311 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.3e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.12 13.3 0.0 1.4 9.9 0.0 2.4 2 DUF1214 Protein of unknown function (DUF1214) 0.54 10.4 7.2 0.055 13.6 1.9 2.0 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter 0.68 10.7 3.1 1.2 10.0 0.1 2.9 2 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 3.5e-09 2.2e-05 56 142 .. 443 537 .. 432 568 .. 0.84 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 3.5e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002311-T1 443 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 535 455444445555679*****9999********9999999999******************************995555.6************96 PP Phage_integrase 141 le 142 + FUN_002311-T1 536 YS 537 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.22 1.4e+03 48 88 .. 113 153 .. 103 157 .. 0.74 2 ? 9.9 0.0 0.00022 1.4 57 108 .. 425 474 .. 406 477 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.22 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_002311-T1 113 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 153 556777778666666767889999**********9985544 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00022 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_002311-T1 425 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 474 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 1.9 8.6e-06 0.055 83 123 .. 72 112 .. 24 123 .. 0.79 2 ? -3.5 0.0 1.6 1e+04 24 42 .. 547 565 .. 534 594 .. 0.52 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8.6e-06 MVD-like_N 83 kvkveSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002311-T1 72 AGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 5556899999********************99988766554 PP == domain 2 score: -3.5 bits; conditional E-value: 1.6 MVD-like_N 24 sSlSltldelytkttvefs 42 +Sl +l++ + + + +++ FUN_002311-T1 547 DSLAAALRHSREQAQSTYD 565 3444444433322222222 PP >> Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.1 0.00019 1.2 1 32 [. 280 311 .. 280 343 .. 0.87 2 ? -0.8 0.5 0.44 2.8e+03 29 69 .. 531 568 .. 520 578 .. 0.71 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 Phage_int_SAM_1 1 ieqfleyLslerglSenTvraYrrdLkaflkf 32 +e++l++L+ rglS T+ ++++ L lk+ FUN_002311-T1 280 LESYLDHLKDHRGLSSATIANHASSLVYPLKY 311 689*******************9998665555 PP == domain 2 score: -0.8 bits; conditional E-value: 0.44 Phage_int_SAM_1 29 flkflseegesleqittsdvraflaelkaeglsasslarrl 69 fl+++ + ++ +++ ++++a l++++++ ++s+ rr FUN_002311-T1 531 FLTWAYS-QSECTDSMKDSLAAALRHSREQ--AQSTYDRRT 568 4444444.7788888888889999998884..567766665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (702 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 719 (0.0281464); expected 510.9 (0.02) Passed bias filter: 495 (0.0193776); expected 510.9 (0.02) Passed Vit filter: 34 (0.00133098); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.35u 0.39s 00:00:00.74 Elapsed: 00:00:00.40 # Mc/sec: 7017.13 // Query: FUN_002312-T1 [L=507] Description: FUN_002312 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002312-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002312-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002312-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002312-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 4978.98 // Query: FUN_002313-T1 [L=264] Description: FUN_002313 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.012 15.7 2.0 0.012 15.7 2.0 1.9 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal Domain annotation for each model (and alignments): >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 2.0 4.8e-07 0.012 81 123 .. 70 112 .. 22 123 .. 0.77 2 ? -1.7 0.6 0.11 2.8e+03 99 113 .. 133 147 .. 124 172 .. 0.51 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 4.8e-07 MVD-like_N 81 elkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 + +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002313-T1 70 DDAGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 555567899999********************99988766554 PP == domain 2 score: -1.7 bits; conditional E-value: 0.11 MVD-like_N 99 ASSasgfAalalala 113 A S ++ A++ ++ + FUN_002313-T1 133 AASTAASASIYVSPS 147 344444444443333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (264 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 796 (0.0311607); expected 510.9 (0.02) Passed bias filter: 488 (0.0191035); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.34u 0.36s 00:00:00.70 Elapsed: 00:00:00.41 # Mc/sec: 2586.87 // Query: FUN_002314-T1 [L=347] Description: FUN_002314 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-06 27.6 0.0 6.2e-06 26.6 0.0 1.5 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.22 12.5 0.0 0.5 11.3 0.0 1.6 1 DUF1214 Protein of unknown function (DUF1214) Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.0 4.9e-10 6.2e-06 56 142 .. 88 182 .. 76 214 .. 0.83 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 4.9e-10 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002314-T1 88 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 180 455444445555679*****9999********9999999999******************************995555.6************97 PP Phage_integrase 141 le 142 + FUN_002314-T1 181 YS 182 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 3.9e-05 0.5 57 108 .. 70 119 .. 39 122 .. 0.86 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 3.9e-05 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_002314-T1 70 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 119 55666664..5789**************999**********99999999988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (347 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 792 (0.0310041); expected 510.9 (0.02) Passed bias filter: 559 (0.021883); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.33u 0.38s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3353.64 // Query: FUN_002315-T1 [L=121] Description: FUN_002315 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 469 (0.0183598); expected 510.9 (0.02) Passed bias filter: 399 (0.0156195); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.35s 00:00:00.62 Elapsed: 00:00:00.40 # Mc/sec: 1215.39 // Query: FUN_002316-T1 [L=162] Description: FUN_002316 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.067 13.8 0.5 0.12 12.9 0.5 1.5 1 DUF1525 Protein of unknown function (DUF1525) 0.29 12.3 4.0 0.15 13.2 1.8 1.6 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> DUF1525 Protein of unknown function (DUF1525) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.5 9.5e-06 0.12 20 70 .. 58 108 .. 52 127 .. 0.89 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 9.5e-06 DUF1525 20 ervielDkaerleaelsaelpadpeqAaalvrqrlqsgkeqlereieaayq 70 +r+ + D +rle+ l ++ p dp++Aa+ + +s +e+++r ++y+ FUN_002316-T1 58 TRIPNEDSLNRLEQFLRNNQPCDPQRAAQATAEDRESIEEARQRASRNSYE 108 56777799********************99999999999999988888775 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.9 0.0 1.2 1.6e+04 10 25 .. 4 19 .. 3 22 .. 0.62 2 ? 13.2 1.8 1.2e-05 0.15 4 60 .. 65 122 .. 63 126 .. 0.89 Alignments for each domain: == domain 1 score: -2.9 bits; conditional E-value: 1.2 DUF4404 10 eeLeedesldeetrak 25 ++L++++++ ++ a+ FUN_002316-T1 4 QQLQRAPEATATSTAT 19 5777777766666555 PP == domain 2 score: 13.2 bits; conditional E-value: 1.2e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002316-T1 65 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 122 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (162 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2649 (0.103699); expected 510.9 (0.02) Passed bias filter: 1157 (0.0452926); expected 510.9 (0.02) Passed Vit filter: 104 (0.00407125); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.36u 0.35s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 1584.96 // Query: FUN_002317-T1 [L=231] Description: FUN_002317 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.024 14.5 0.8 0.024 14.5 0.8 1.8 2 UPF0524 UPF0524 of C3orf70 0.026 14.7 1.6 0.026 14.7 1.6 1.9 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal Domain annotation for each model (and alignments): >> UPF0524 UPF0524 of C3orf70 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.8 1.8e-06 0.024 154 204 .. 42 96 .. 11 126 .. 0.69 2 ? -0.9 0.4 0.091 1.2e+03 149 176 .. 140 166 .. 111 178 .. 0.43 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.8e-06 UPF0524 154 ekqlakekakgpkldhcsspsssedsginal....glhylescdeeeeeedelss 204 ++++++ ++ dh s+s dsgi a+ g y+ s e+ee+++e+s FUN_002317-T1 42 AQATTRVLVHLQVNDHACQGSASSDSGIAAIttaaGPIYVASSSESEEQDNEFSR 96 233444445566679*************9874443667*************9985 PP == domain 2 score: -0.9 bits; conditional E-value: 0.091 UPF0524 149 kkeaaekqlakekakgpkldhcsspsss 176 ++++++++ ++a g +d ss s s FUN_002317-T1 140 DVASEDSEIIPSTAVGAPIDV-SSSSES 166 222222223333333333332.222333 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 1.6 2e-06 0.026 71 123 .. 37 87 .. 10 100 .. 0.65 2 ? -1.1 0.9 0.14 1.8e+03 94 110 .. 107 119 .. 85 147 .. 0.57 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 2e-06 MVD-like_N 71 evrelakelselkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 + a+ +++v v+ + n g ASS+sg Aa+++a+ ++ + se+ FUN_002317-T1 37 SWSQIAQ--ATTRVLVHLQVNDHACQGSASSDSGIAAITTAAGPIYVASSSES 87 3444444..44445555444555568****************99988666554 PP == domain 2 score: -1.1 bits; conditional E-value: 0.14 MVD-like_N 94 taaglASSasgfAalal 110 +aa A Sas + + FUN_002317-T1 107 MAASTAASASIY----V 119 444444444433....3 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (231 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 709 (0.0277549); expected 510.9 (0.02) Passed bias filter: 428 (0.0167547); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2353.77 // Query: FUN_002318-T1 [L=334] Description: FUN_002318 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (334 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1022 (0.0400078); expected 510.9 (0.02) Passed bias filter: 778 (0.0304561); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.41s 00:00:00.75 Elapsed: 00:00:00.43 # Mc/sec: 3163.25 // Query: FUN_002319-T1 [L=507] Description: FUN_002319 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002319-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002319-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002319-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002319-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.40u 0.36s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 4917.26 // Query: FUN_002320-T1 [L=675] Description: FUN_002320 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-05 25.8 0.0 2.1e-05 24.8 0.0 1.4 1 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.12 13.4 0.0 1.4 10.0 0.0 2.3 2 DUF1214 Protein of unknown function (DUF1214) 1.3 9.2 8.2 0.76 9.9 5.4 2.0 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 2.5e-09 2.1e-05 56 142 .. 386 480 .. 375 511 .. 0.84 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 2.5e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatrL 140 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002320-T1 386 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTWA 478 455444445555679*****9999********9999999999******************************995555.6************96 PP Phage_integrase 141 le 142 + FUN_002320-T1 479 YS 480 65 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.16 1.3e+03 48 88 .. 88 128 .. 78 132 .. 0.74 2 ? 10.0 0.0 0.00016 1.4 57 108 .. 368 417 .. 349 420 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.16 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_002320-T1 88 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 128 556777778666666767889999**********9985544 PP == domain 2 score: 10.0 bits; conditional E-value: 0.00016 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_002320-T1 368 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 417 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 5.4 9e-05 0.76 86 123 .. 50 87 .. 25 133 .. 0.85 2 ? -3.4 0.0 1.1 9.3e+03 24 42 .. 490 508 .. 477 538 .. 0.52 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 9e-05 MVD-like_N 86 veSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002320-T1 50 CASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 87 57889999*******************99988666554 PP == domain 2 score: -3.4 bits; conditional E-value: 1.1 MVD-like_N 24 sSlSltldelytkttvefs 42 +Sl +l++ + + + +++ FUN_002320-T1 490 DSLAAALRHSREQAQSTYD 508 3444444433322222222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (675 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1062 (0.0415737); expected 510.9 (0.02) Passed bias filter: 717 (0.0280681); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.41u 0.36s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 6431.35 // Query: FUN_002321-T1 [L=507] Description: FUN_002321 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.53 10.8 4.4 0.48 10.9 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 3 9.0 4.8 1.1 10.5 1.8 1.8 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 0.21 2.7e+03 20 27 .. 300 307 .. 293 311 .. 0.69 2 ? 10.9 2.0 3.8e-05 0.48 22 33 .. 321 333 .. 318 342 .. 0.86 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 0.21 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002321-T1 300 SQAECTCL 307 55677775 PP == domain 2 score: 10.9 bits; conditional E-value: 3.8e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002321-T1 321 QNCPyCICTEEGG 333 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.1 2 2.6e+04 17 34 .. 84 101 .. 82 115 .. 0.70 2 ? 10.5 1.8 8.5e-05 1.1 4 60 .. 239 296 .. 237 300 .. 0.89 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 2 DUF4404 17 sldeetrakLeelaedie 34 s+de+++ +L++ +d e FUN_002321-T1 84 SADEDQEPELSNSSSDSE 101 678888888877766655 PP == domain 2 score: 10.5 bits; conditional E-value: 8.5e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002321-T1 239 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 296 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (507 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2086 (0.0816598); expected 510.9 (0.02) Passed bias filter: 850 (0.0332746); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.41u 0.37s 00:00:00.78 Elapsed: 00:00:00.42 # Mc/sec: 4810.71 // Query: FUN_002322-T1 [L=539] Description: FUN_002322 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.2e-06 26.0 0.0 2.8e-05 24.4 0.0 1.7 2 Phage_integrase Phage integrase family ------ inclusion threshold ------ 0.067 14.2 0.0 1 10.4 0.0 2.4 2 DUF1214 Protein of unknown function (DUF1214) 0.25 11.5 6.2 0.25 11.5 4.7 1.8 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-ter Domain annotation for each model (and alignments): >> Phage_integrase Phage integrase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 1.1 9.6e+03 84 110 .. 15 41 .. 8 42 .. 0.80 2 ! 24.4 0.0 3.3e-09 2.8e-05 56 139 .. 443 534 .. 432 538 .. 0.85 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.1 Phage_integrase 84 skrlkeaeesealFlskkgkplsrqtv 110 s + +++++++++ s k +pls++++ FUN_002322-T1 15 SSEDEKDSDQTYVYSSSKLSPLSASEF 41 445678899999999999999999876 PP == domain 2 score: 24.4 bits; conditional E-value: 3.3e-09 Phage_integrase 56 vrv...ergKgnkertvpls..eealellkellskr....lkeaeesealFlskkgkplsrqtvkkafkrlvkeagleerlhpHelRhsfatr 139 ++v + +K + tvp++ +e+++ +++++++ ++++e++++lF++ +g+p s ++++k +k+l ++ +++ ++lR sf t+ FUN_002322-T1 443 IYVqnyKTSKFAGSDTVPIQadSELCSFFRKYVQEFrpelSSAQEKNDFLFVNANGQPYSGSSFSKHLKNLMIRLTGR-EVSINTLRSSFLTW 534 455444445555679*****9999********9999999999******************************995555.6**********998 PP >> DUF1214 Protein of unknown function (DUF1214) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 0.12 1e+03 48 88 .. 113 153 .. 103 157 .. 0.74 2 ? 10.4 0.0 0.00012 1 57 108 .. 425 474 .. 406 477 .. 0.84 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.12 DUF1214 48 flveneldrysigsrtlkglkknaDGsltiylspeapegkk 88 + +ne r + s +l+ + +++ +s iy+sp+++++++ FUN_002322-T1 113 EEQDNEFSRLPLLSDDLEIMAASTAASASIYVSPSSESEDQ 153 556777788666666767889999**********9985544 PP == domain 2 score: 10.4 bits; conditional E-value: 0.00012 DUF1214 57 ysigsrtlkglkknaDGsltiylspeapegkkeaNWLptpaggefelvlRlY 108 +++ +r++ + ++DG +tiy+++ + ++ +++ +p++a+ e+ +R Y FUN_002322-T1 425 ARFANRNV--ALLQKDGGITIYVQNYKTSKFAGSDTVPIQADSELCSFFRKY 474 55666664..5789**************9999*********99999999988 PP >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 4.7 2.9e-05 0.25 82 123 .. 71 112 .. 23 140 .. 0.81 2 ? -2.4 0.2 0.54 4.6e+03 94 109 .. 132 143 .. 112 169 .. 0.60 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 2.9e-05 MVD-like_N 82 lkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002322-T1 71 DAGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 55556899999********************99988666554 PP == domain 2 score: -2.4 bits; conditional E-value: 0.54 MVD-like_N 94 taaglASSasgfAala 109 +aa A Sas + FUN_002322-T1 132 MAASTAASAS----IY 143 3333333433....33 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (539 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 884 (0.0346056); expected 510.9 (0.02) Passed bias filter: 667 (0.0261108); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.41s 00:00:00.74 Elapsed: 00:00:00.41 # Mc/sec: 5340.80 // Query: FUN_002323-T1 [L=473] Description: FUN_002323 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.46 10.9 4.4 0.45 11.0 2.0 2.1 2 VWC2L_1st VWC2L-like, N-terminal domain 2.6 9.2 4.8 0.98 10.6 1.8 1.9 2 DUF4404 Domain of unknown function (DUF4404) Domain annotation for each model (and alignments): >> VWC2L_1st VWC2L-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 0.2 2.5e+03 20 27 .. 266 273 .. 259 277 .. 0.69 2 ? 11.0 2.0 3.5e-05 0.45 22 33 .. 287 299 .. 284 308 .. 0.86 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.2 VWC2L_1st 20 spsaCpCt 27 s+ +C+C+ FUN_002323-T1 266 SQAECTCL 273 55677775 PP == domain 2 score: 11.0 bits; conditional E-value: 3.5e-05 VWC2L_1st 22 saCp.CtCTeeGp 33 ++Cp C CTeeG FUN_002323-T1 287 QNCPyCICTEEGG 299 79*********95 PP >> DUF4404 Domain of unknown function (DUF4404) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.4 0.1 1.8 2.3e+04 17 35 .. 50 68 .. 48 87 .. 0.72 2 ? 10.6 1.8 7.7e-05 0.98 4 60 .. 205 262 .. 203 266 .. 0.89 Alignments for each domain: == domain 1 score: -3.4 bits; conditional E-value: 1.8 DUF4404 17 sldeetrakLeelaediee 35 s+de+++ +L++ +d e FUN_002323-T1 50 SADEDQEPELSNSSSDSEL 68 6788888888777666555 PP == domain 2 score: 10.6 bits; conditional E-value: 7.7e-05 DUF4404 4 lLekLheeLeedesldeetrakLeela.edieellaeedaaaeekelvdrlneaverF 60 +L++L++ L+++++ d + +a+ ++ + e+iee+ ++ + ++ e++++ +++e ++ F FUN_002323-T1 205 SLNRLEQFLRNNQPCDPQRAAQATAEDrESIEEARQRASRNSYEEQRAQQVQEKIKDF 262 799****************99988776167**************99********9998 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (473 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1956 (0.0765708); expected 510.9 (0.02) Passed bias filter: 755 (0.0295557); expected 510.9 (0.02) Passed Vit filter: 50 (0.00195733); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.38u 0.39s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4511.63 // Query: FUN_002324-T1 [L=235] Description: FUN_002324 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 R1_ABCA1 ABCA1-like, C-terminal R1 regulatory domain Domain annotation for each model (and alignments): >> R1_ABCA1 ABCA1-like, C-terminal R1 regulatory domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 9.5e-06 0.24 18 75 .] 165 222 .. 157 222 .. 0.90 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 9.5e-06 R1_ABCA1 18 eavkefiqlsFPgsvlkeqhlnmleYqlpskalslakiFslLeenkeelniedYsVsQ 75 ++v+ + + FP + ++h+++l+ ++ ++a + + L++ k +n +YsV+Q FUN_002324-T1 165 SDVSVQFMHGFPRRLITDHHRGLLRGNITVAARISNQAVRSLSAGKLIYNASQYSVTQ 222 6677777788**********************999999******************99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (235 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 576 (0.0225484); expected 510.9 (0.02) Passed bias filter: 491 (0.019221); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2359.33 // Query: FUN_002325-T1 [L=479] Description: FUN_002325 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.027 14.6 1.8 0.027 14.6 1.8 1.8 2 MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal Domain annotation for each model (and alignments): >> MVD-like_N Diphosphomevalonate decarboxylase-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 1.8 1.1e-06 0.027 81 123 .. 70 112 .. 23 128 .. 0.79 2 ? -2.4 0.1 0.18 4.7e+03 99 112 .. 133 146 .. 124 171 .. 0.53 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 1.1e-06 MVD-like_N 81 elkvkveSennfptaaglASSasgfAalalalaklaglelsek 123 + +S+ + p +g ASS+sg Aa+++a+ ++ + se+ FUN_002325-T1 70 DDAGPCASSSKRPRLSGSASSDSGIAAITTAAGPIYVASSSES 112 455566899999********************99988666554 PP == domain 2 score: -2.4 bits; conditional E-value: 0.18 MVD-like_N 99 ASSasgfAalalal 112 A S ++ A++ ++ FUN_002325-T1 133 AASTAASASIYVSP 146 33444444443333 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (479 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 664 (0.0259933); expected 510.9 (0.02) Passed bias filter: 472 (0.0184772); expected 510.9 (0.02) Passed Vit filter: 24 (0.000939518); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.36u 0.36s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 4601.79 // Query: FUN_002326-T1 [L=158] Description: FUN_002326 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (158 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 827 (0.0323742); expected 510.9 (0.02) Passed bias filter: 595 (0.0232922); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.40s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1590.84 // Query: FUN_002327-T1 [L=1328] Description: FUN_002327 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-165 537.4 50.7 3e-16 59.9 0.5 13.0 12 TPR_12 Tetratricopeptide repeat 7.5e-149 471.8 46.2 4.5e-08 33.1 0.0 21.7 21 TPR_7 Tetratricopeptide repeat 4.2e-122 394.0 115.4 1.9e-07 31.1 0.7 22.2 22 TPR_1 Tetratricopeptide repeat 1.4e-80 263.7 40.1 0.0007 20.0 0.0 21.6 21 TPR_10 Tetratricopeptide repeat 1.4e-71 231.1 93.6 0.00049 20.5 0.2 22.2 22 TPR_8 Tetratricopeptide repeat 5.1e-50 171.0 0.0 7.7e-50 170.4 0.0 1.2 1 CHAT CHAT domain 3.8e-47 155.0 96.6 0.0093 16.5 0.8 22.1 22 TPR_2 Tetratricopeptide repeat 1.3e-23 81.7 51.0 3.7 8.5 0.1 19.9 19 TPR_17 Tetratricopeptide repeat 3.4e-22 77.2 43.5 24 6.5 0.1 21.6 21 TPR_14 Tetratricopeptide repeat 2.4e-17 63.7 0.3 0.018 14.8 0.0 6.6 7 TPR_MalT MalT-like TPR region 3.5e-17 62.7 38.2 0.54 10.9 0.1 17.7 20 Rapsyn_N Rapsyn N-terminal myristoylation a 1.9e-15 57.2 0.4 89 3.8 0.0 16.1 17 DUF2977 Protein of unknown function (DUF29 4.7e-15 55.6 27.4 61 5.1 0.0 18.5 19 TPR_6 Tetratricopeptide repeat 1e-14 55.2 2.9 0.015 15.2 0.0 6.2 6 SNAP Soluble NSF attachment protein, SN 2e-14 53.5 14.0 30 4.9 0.0 17.1 20 DUF7542 Family of unknown function (DUF754 9.8e-13 48.6 14.0 5.7 6.8 0.0 15.3 17 TPR_15 Tetratricopeptide repeat 7.1e-11 42.6 0.0 16 6.2 0.0 10.3 12 WH_Halo_primase Halobacteria primase winged helix 1.7e-10 40.9 9.0 99 4.5 0.0 12.8 12 TPR_4 Tetratricopeptide repeat 5.6e-07 29.9 28.4 42 4.3 0.0 15.0 18 RPN7 26S proteasome subunit RPN7 1.1e-06 29.4 39.7 1.8 9.6 0.3 14.7 15 TPR_16 Tetratricopeptide repeat 5.8e-06 26.7 0.3 4.3e+02 1.5 0.0 10.5 14 CODH_A_N Carbon monoxide dehydrogenase subu 6.6e-06 26.3 13.9 44 4.4 0.0 12.1 14 DUF1965 Domain of unknown function (DUF196 4.9e-05 23.8 41.7 22 6.1 0.0 18.0 19 PPR PPR repeat 0.00039 20.4 1.0 36 4.1 0.0 6.8 10 TPR_NPHP3 Nephrocystin-3 TPR domain 0.0004 21.3 21.7 57 4.7 0.0 11.5 12 Rhodanese Rhodanese-like domain 0.0019 19.0 21.6 27 5.6 0.1 11.7 14 TPR_19 Tetratricopeptide repeat 0.0026 18.2 0.0 1e+02 3.5 0.0 7.8 9 DUF6225 Family of unknown function (DUF622 0.0098 16.3 0.0 43 4.7 0.0 5.9 3 RCF1-5-like_lid RCF1/5-like, AAA+ ATPase lid domai ------ inclusion threshold ------ 0.022 15.6 30.9 55 4.7 0.1 13.6 14 ANAPC3 Anaphase-promoting complex, cyclos 0.044 14.5 0.0 64 4.3 0.0 6.2 6 NAD_binding_11 NAD-binding of NADP-dependent 3-hy 0.1 13.5 14.3 40 5.2 0.1 9.6 11 Bleomycin_resist_prot_dom Bleomycin resistance protein domai 0.1 12.4 0.8 63 3.2 0.0 5.3 8 Vps54_N Vacuolar-sorting protein 54, of GA 0.28 10.3 0.0 11 5.1 0.0 3.6 5 Transferase Transferase family 0.7 10.4 14.8 53 4.3 0.0 6.9 6 DUF386 YhcH/YjgK/YiaL Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.0 0.5 2.3e-06 0.0017 16 75 .. 8 65 .. 5 67 .. 0.93 2 ! 58.9 1.5 7.7e-19 5.8e-16 4 75 .. 76 145 .. 73 147 .. 0.96 3 ! 51.7 0.1 1.4e-16 1.1e-13 5 74 .. 157 224 .. 153 227 .. 0.96 4 ! 56.5 0.2 4.5e-18 3.4e-15 6 75 .. 198 265 .. 195 267 .. 0.96 5 ! 57.4 0.3 2.4e-18 1.8e-15 4 75 .. 276 345 .. 273 347 .. 0.96 6 ! 51.4 0.0 1.7e-16 1.3e-13 9 75 .. 361 425 .. 354 427 .. 0.95 7 ! 59.9 0.5 4e-19 3e-16 4 75 .. 436 505 .. 433 507 .. 0.96 8 ! 52.2 0.1 9.6e-17 7.2e-14 5 74 .. 517 584 .. 514 587 .. 0.96 9 ! 34.2 0.2 4.1e-11 3.1e-08 22 75 .. 574 625 .. 574 627 .. 0.96 10 ! 57.0 0.3 3.1e-18 2.4e-15 4 75 .. 636 705 .. 633 707 .. 0.96 11 ! 59.5 0.5 5.3e-19 4e-16 4 75 .. 716 785 .. 713 787 .. 0.95 12 ! 48.3 0.0 1.6e-15 1.2e-12 4 75 .. 796 865 .. 793 867 .. 0.95 Alignments for each domain: == domain 1 score: 19.0 bits; conditional E-value: 2.3e-06 TPR_12 16 lgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +g + +A e++ek l + ++ +d+ + a++nL +++ l d+++A++++e+ leia FUN_002327-T1 8 QGYFRKASEYHEKHLKITMEV--GDRAREEKAYQNLPYAFQSLDDFRKAIKYHEKHLEIA 65 666789***************..9999*******************************98 PP == domain 2 score: 58.9 bits; conditional E-value: 7.7e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg+ +A+e++ek le+a ++ +++ ++ +a+rnLg +y++lgd ++A+e++e+ leia FUN_002327-T1 76 NAYGNLGNAYQLLGDVRKAIEYHEKHLEIAIEV--GHRVGEGNAYRNLGNAYQLLGDVRKAIEYHEKHLEIA 145 799******************************..99*********************************98 PP == domain 3 score: 51.7 bits; conditional E-value: 1.4e-16 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +++nl++++r lg++ + +e++e+ l +a ++ +d+ ++ + nLg++y+ lgd+++A+e++e+ lei FUN_002327-T1 157 TYRNLGNAYRSLGEFRKGIEYHERHLKIAIEV--GDRAGEGSGYGNLGITYQSLGDFRKAIEYHEKHLEI 224 799*****************************..99********************************98 PP == domain 4 score: 56.5 bits; conditional E-value: 4.5e-18 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 + nl+ +++ lg++ +A+e++ek le+ +++ +d+ ++ ta+ nLg +y+ l d+++A+e++e+ leia FUN_002327-T1 198 YGNLGITYQSLGDFRKAIEYHEKHLEIEREI--GDRTGEGTAYGNLGNAYESLSDFRKAIEYHEKHLEIA 265 789****************************..8999*******************************98 PP == domain 5 score: 57.4 bits; conditional E-value: 2.4e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ek le+a ++ +++ ++ +a+ n g++y+ lgd+++A+e++e+ l+ia FUN_002327-T1 276 SAYGYLGNAYQSLGDFRKAIEYHEKHLEIAIEV--GNRVGQGNAYGNFGIAYRSLGDLRKAIEYHEKHLKIA 345 68888****************************..99*********************************98 PP == domain 6 score: 51.4 bits; conditional E-value: 1.7e-16 TPR_12 9 lAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +++++ lg++ +A+e++ek le+a ++ +++ + +a+ nLg +y+ lgd ++A+e++e+ l+ia FUN_002327-T1 361 FGNTYQSLGDFRKAIEYHEKHLEIAIEV--GNWVGKGNAYGNLGNAYQSLGDVRKAIEYHEKHLKIA 425 699*************************..9**********************************98 PP == domain 7 score: 59.9 bits; conditional E-value: 4e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a ++ +d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia FUN_002327-T1 436 NAYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEV--GDRVGEGSAYGSLGSAYRSLGDLRKAIEYHEKHLEIA 505 799******************************..9**********************************98 PP == domain 8 score: 52.2 bits; conditional E-value: 9.6e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 ++ nl++++r lg++ + +e++e+ l +a ++ +d+ ++ a+ nLg++y+ lgd+++A+e++e+ ei FUN_002327-T1 517 TYGNLGNAYRSLGEFRKGIEYHERHLKIAIEV--GDRVGEGSAYGNLGIAYQSLGDFRKAIEYHEKHSEI 584 799*****************************..9******************************99887 PP == domain 9 score: 34.2 bits; conditional E-value: 4.1e-11 TPR_12 22 AlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 A+e++ek e+ +++ +d+ ++ ta+ nLg +y+ lgd+++A e++e+ l+ia FUN_002327-T1 574 AIEYHEKHSEIEREV--GDRTGEGTAYGNLGNAYQSLGDFRKANEYHEKHLKIA 625 89*************..9999*******************************98 PP == domain 10 score: 57.0 bits; conditional E-value: 3.1e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a ++ +d+ ++ a+ g +y+ lgd ++A+e++e+ leia FUN_002327-T1 636 NAYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEV--GDRVGEGSAYGSFGSAYRSLGDSRKAIEYHEKHLEIA 705 799******************************..9**********************************98 PP == domain 11 score: 59.5 bits; conditional E-value: 5.3e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a ++ +d++++ +a+ Lgr+y+ lgd+++A+e++e+ leia FUN_002327-T1 716 NAYGNLGNAYQLLGDFRKAIEYHEKQLEIAIEV--GDRDGEGNAYGSLGRAYQSLGDFRKAIEYHEKDLEIA 785 799******************************..89999**************************988886 PP == domain 12 score: 48.3 bits; conditional E-value: 1.6e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a+++ +d+ ++ ++++n+g y+ lg++e Al ++ a++++ FUN_002327-T1 796 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--GDRVGEGITYHNMGGEYFSLGQFEIALGMFVSAVKVF 865 799******************************..99***************************99998876 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.0 0.00086 0.64 9 36 .] 5 32 .. 4 32 .. 0.96 2 ! 14.5 0.0 5.2e-05 0.039 2 35 .. 38 71 .. 37 72 .. 0.89 3 ! 25.6 0.1 1.4e-08 1.1e-05 1 35 [. 77 111 .. 77 112 .. 0.94 4 ! 25.7 0.1 1.4e-08 1e-05 1 35 [. 117 151 .. 117 152 .. 0.94 5 ! 19.1 0.0 1.8e-06 0.0013 2 36 .] 158 192 .. 157 192 .. 0.94 6 ! 25.7 0.0 1.3e-08 1e-05 3 35 .. 199 231 .. 198 232 .. 0.94 7 ! 25.0 0.0 2.3e-08 1.7e-05 1 35 [. 237 271 .. 237 272 .. 0.93 8 ! 23.8 0.0 5.6e-08 4.2e-05 5 35 .. 281 311 .. 277 312 .. 0.91 9 ! 18.8 0.0 2.2e-06 0.0016 2 35 .. 318 351 .. 317 352 .. 0.90 10 ! 19.0 0.0 2e-06 0.0015 6 31 .. 362 387 .. 359 390 .. 0.90 11 ! 25.3 0.0 1.8e-08 1.3e-05 1 35 [. 397 431 .. 397 432 .. 0.93 12 ! 26.8 0.1 6e-09 4.5e-06 1 35 [. 437 471 .. 437 472 .. 0.95 13 ! 25.4 0.1 1.7e-08 1.3e-05 1 35 [. 477 511 .. 477 512 .. 0.93 14 ! 19.4 0.0 1.5e-06 0.0011 1 35 [. 517 551 .. 517 552 .. 0.94 15 ! 25.9 0.0 1.1e-08 8.5e-06 1 35 [. 557 591 .. 557 592 .. 0.96 16 ! 21.3 0.0 3.5e-07 0.00027 1 35 [. 597 631 .. 597 632 .. 0.95 17 ! 26.8 0.1 6e-09 4.5e-06 1 35 [. 637 671 .. 637 672 .. 0.95 18 ! 20.4 0.0 6.8e-07 0.00051 5 36 .] 681 712 .. 677 712 .. 0.89 19 ! 28.3 0.1 2e-09 1.5e-06 1 35 [. 717 751 .. 717 752 .. 0.95 20 ! 25.3 0.0 1.8e-08 1.4e-05 1 35 [. 757 791 .. 757 792 .. 0.92 21 ! 33.1 0.0 6e-11 4.5e-08 1 35 [. 797 831 .. 797 832 .. 0.96 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00086 TPR_7 9 yrklGdydeAirlyerlLalakdpedre 36 y ++G +++A +++e++L ++++ +dr+ FUN_002327-T1 5 YISQGYFRKASEYHEKHLKITMEVGDRA 32 899**********************995 PP == domain 2 score: 14.5 bits; conditional E-value: 5.2e-05 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +L ++++l d+++Ai+++e++L++a + +dr FUN_002327-T1 38 YQNLPYAFQSLDDFRKAIKYHEKHLEIAIEVGDR 71 667778999*******************999997 PP == domain 3 score: 25.6 bits; conditional E-value: 1.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd ++Ai+++e++L++a + ++r FUN_002327-T1 77 AYGNLGNAYQLLGDVRKAIEYHEKHLEIAIEVGHR 111 789*************************9988876 PP == domain 4 score: 25.7 bits; conditional E-value: 1.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+++y+ lGd ++Ai+++e++L++a + +dr FUN_002327-T1 117 AYRNLGNAYQLLGDVRKAIEYHEKHLEIAIEVGDR 151 678**************************999997 PP == domain 5 score: 19.1 bits; conditional E-value: 1.8e-06 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedre 36 + +L+++yr+lG++++ i+++er+L +a + +dr+ FUN_002327-T1 158 YRNLGNAYRSLGEFRKGIEYHERHLKIAIEVGDRA 192 679*************************9999985 PP == domain 6 score: 25.7 bits; conditional E-value: 1.3e-08 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 ++L+ +y++lGd+++Ai+++e++L++ ++ +dr FUN_002327-T1 199 GNLGITYQSLGDFRKAIEYHEKHLEIEREIGDR 231 79**************************99998 PP == domain 7 score: 25.0 bits; conditional E-value: 2.3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++l d+++Ai+++e++L++a + ++r FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEYHEKHLEIAIEVGNR 271 789*************************9888876 PP == domain 8 score: 23.8 bits; conditional E-value: 5.6e-08 TPR_7 5 LariyrklGdydeAirlyerlLalakdpedr 35 L+++y++lGd+++Ai+++e++L++a + ++r FUN_002327-T1 281 LGNAYQSLGDFRKAIEYHEKHLEIAIEVGNR 311 9***********************9888876 PP == domain 9 score: 18.8 bits; conditional E-value: 2.2e-06 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++ + +yr+lGd ++Ai+++e++L +a + +dr FUN_002327-T1 318 YGNFGIAYRSLGDLRKAIEYHEKHLKIAIEVGDR 351 677799*********************9999987 PP == domain 10 score: 19.0 bits; conditional E-value: 2e-06 TPR_7 6 ariyrklGdydeAirlyerlLalakd 31 +++y++lGd+++Ai+++e++L++a + FUN_002327-T1 362 GNTYQSLGDFRKAIEYHEKHLEIAIE 387 89********************9865 PP == domain 11 score: 25.3 bits; conditional E-value: 1.8e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd ++Ai+++e++L +a + ++r FUN_002327-T1 397 AYGNLGNAYQSLGDVRKAIEYHEKHLKIAIEVGHR 431 789************************99888876 PP == domain 12 score: 26.8 bits; conditional E-value: 6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y lGd+++Ai+++e++L++a + +dr FUN_002327-T1 437 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEVGDR 471 789**************************999997 PP == domain 13 score: 25.4 bits; conditional E-value: 1.7e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd ++Ai+++e++L++a + ++r FUN_002327-T1 477 AYGSLGSAYRSLGDLRKAIEYHEKHLEIAIEVGNR 511 7899************************9888876 PP == domain 14 score: 19.4 bits; conditional E-value: 1.5e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 ++++L+++yr+lG++++ i+++er+L +a + +dr FUN_002327-T1 517 TYGNLGNAYRSLGEFRKGIEYHERHLKIAIEVGDR 551 578*************************9999987 PP == domain 15 score: 25.9 bits; conditional E-value: 1.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++ ++ ++ +dr FUN_002327-T1 557 AYGNLGIAYQSLGDFRKAIEYHEKHSEIEREVGDR 591 789*****************************998 PP == domain 16 score: 21.3 bits; conditional E-value: 3.5e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++A +++e++L +a + +dr FUN_002327-T1 597 AYGNLGNAYQSLGDFRKANEYHEKHLKIAIEVGDR 631 789*************************9999987 PP == domain 17 score: 26.8 bits; conditional E-value: 6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y lGd+++Ai+++e++L++a + +dr FUN_002327-T1 637 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEVGDR 671 789**************************999997 PP == domain 18 score: 20.4 bits; conditional E-value: 6.8e-07 TPR_7 5 LariyrklGdydeAirlyerlLalakdpedre 36 +++yr+lGd ++Ai+++e++L++a + ++re FUN_002327-T1 681 FGSAYRSLGDSRKAIEYHEKHLEIAIEVGKRE 712 589**********************9988876 PP == domain 19 score: 28.3 bits; conditional E-value: 2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd+++Ai+++e++L++a + +dr FUN_002327-T1 717 AYGNLGNAYQLLGDFRKAIEYHEKQLEIAIEVGDR 751 789**************************999997 PP == domain 20 score: 25.3 bits; conditional E-value: 1.8e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+r+y++lGd+++Ai+++e+ L++a + ++r FUN_002327-T1 757 AYGSLGRAYQSLGDFRKAIEYHEKDLEIAIEVGNR 791 7899***********************99887765 PP == domain 21 score: 33.1 bits; conditional E-value: 6e-11 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002327-T1 797 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVGDR 831 789******************************98 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.2 5.1 3.9e+03 11 30 .. 5 24 .. 4 24 .. 0.74 2 ! 9.8 0.5 0.0013 1 3 30 .. 37 64 .. 35 65 .. 0.87 3 ! 26.2 0.8 9.1e-09 6.9e-06 2 30 .. 76 104 .. 75 105 .. 0.95 4 ! 25.0 0.8 2.1e-08 1.6e-05 2 30 .. 116 144 .. 115 145 .. 0.95 5 ! 19.1 0.1 1.6e-06 0.0012 4 30 .. 158 184 .. 157 185 .. 0.94 6 ! 26.2 0.0 8.9e-09 6.7e-06 3 31 .. 197 225 .. 196 227 .. 0.93 7 ! 26.2 0.2 9e-09 6.8e-06 3 30 .. 237 264 .. 236 265 .. 0.96 8 ! 26.8 0.6 5.5e-09 4.1e-06 3 30 .. 277 304 .. 275 305 .. 0.95 9 ! 17.6 0.4 4.6e-06 0.0034 3 30 .. 317 344 .. 315 345 .. 0.92 10 ! 18.5 0.1 2.5e-06 0.0018 8 30 .. 362 384 .. 358 385 .. 0.96 11 ! 26.4 0.5 7.7e-09 5.8e-06 2 30 .. 396 424 .. 395 425 .. 0.95 12 ! 30.1 1.8 5.2e-10 3.9e-07 2 30 .. 436 464 .. 435 465 .. 0.95 13 ! 22.3 0.1 1.5e-07 0.00011 3 30 .. 477 504 .. 475 505 .. 0.95 14 ! 20.1 0.1 7.6e-07 0.00057 3 30 .. 517 544 .. 517 545 .. 0.95 15 ! 24.4 0.1 3.4e-08 2.5e-05 3 27 .. 557 581 .. 555 587 .. 0.89 16 ! 19.7 0.6 1e-06 0.00078 3 30 .. 597 624 .. 596 625 .. 0.95 17 ! 30.1 1.8 5.2e-10 3.9e-07 2 30 .. 636 664 .. 635 665 .. 0.95 18 ! 13.2 0.1 0.00011 0.086 8 30 .. 682 704 .. 677 705 .. 0.94 19 ! 25.0 1.2 2.1e-08 1.6e-05 2 26 .. 716 740 .. 715 745 .. 0.90 20 ! 18.9 0.2 1.8e-06 0.0014 2 26 .. 756 780 .. 755 785 .. 0.93 21 ! 31.1 0.7 2.5e-10 1.9e-07 2 31 .. 796 825 .. 795 827 .. 0.94 22 ! 8.1 0.0 0.0047 3.5 3 29 .. 837 863 .. 836 865 .. 0.85 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 5.1 TPR_1 11 yfklgkydeAleyyekALel 30 y ++g + +A ey ek L++ FUN_002327-T1 5 YISQGYFRKASEYHEKHLKI 24 55666688899999998876 PP == domain 2 score: 9.8 bits; conditional E-value: 0.0013 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nl +a+++l ++ +A++y ek Le+ FUN_002327-T1 37 AYQNLPYAFQSLDDFRKAIKYHEKHLEI 64 666666899*****************98 PP == domain 3 score: 26.2 bits; conditional E-value: 9.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay+ lg+ +A+ey ek Le+ FUN_002327-T1 76 NAYGNLGNAYQLLGDVRKAIEYHEKHLEI 104 69*************************98 PP == domain 4 score: 25.0 bits; conditional E-value: 2.1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay+ lg+ +A+ey ek Le+ FUN_002327-T1 116 NAYRNLGNAYQLLGDVRKAIEYHEKHLEI 144 59*************************98 PP == domain 5 score: 19.1 bits; conditional E-value: 1.6e-06 TPR_1 4 lynlGnayfklgkydeAleyyekALel 30 + nlGnay++lg++ + +ey e+ L++ FUN_002327-T1 158 YRNLGNAYRSLGEFRKGIEYHERHLKI 184 88**********************998 PP == domain 6 score: 26.2 bits; conditional E-value: 8.9e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 + nlG +y++lg++ +A+ey ek Le++ FUN_002327-T1 197 GYGNLGITYQSLGDFRKAIEYHEKHLEIE 225 599************************97 PP == domain 7 score: 26.2 bits; conditional E-value: 9e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay +l ++ +A+ey ek Le+ FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEYHEKHLEI 264 8*************************98 PP == domain 8 score: 26.8 bits; conditional E-value: 5.5e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lGnay++lg++ +A+ey ek Le+ FUN_002327-T1 277 AYGYLGNAYQSLGDFRKAIEYHEKHLEI 304 99************************98 PP == domain 9 score: 17.6 bits; conditional E-value: 4.6e-06 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ n G ay++lg++ +A+ey ek L++ FUN_002327-T1 317 AYGNFGIAYRSLGDLRKAIEYHEKHLKI 344 88888*********************98 PP == domain 10 score: 18.5 bits; conditional E-value: 2.5e-06 TPR_1 8 GnayfklgkydeAleyyekALel 30 Gn+y++lg++ +A+ey ek Le+ FUN_002327-T1 362 GNTYQSLGDFRKAIEYHEKHLEI 384 9********************98 PP == domain 11 score: 26.4 bits; conditional E-value: 7.7e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg+ +A+ey ek L++ FUN_002327-T1 396 NAYGNLGNAYQSLGDVRKAIEYHEKHLKI 424 69*************************98 PP == domain 12 score: 30.1 bits; conditional E-value: 5.2e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay+ lg++ +A+ey ek Le+ FUN_002327-T1 436 NAYGNLGNAYYLLGDFRKAIEYHEKHLEI 464 69*************************98 PP == domain 13 score: 22.3 bits; conditional E-value: 1.5e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lG ay++lg++ +A+ey ek Le+ FUN_002327-T1 477 AYGSLGSAYRSLGDLRKAIEYHEKHLEI 504 89************************98 PP == domain 14 score: 20.1 bits; conditional E-value: 7.6e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 ++ nlGnay++lg++ + +ey e+ L++ FUN_002327-T1 517 TYGNLGNAYRSLGEFRKGIEYHERHLKI 544 599**********************998 PP == domain 15 score: 24.4 bits; conditional E-value: 3.4e-08 TPR_1 3 alynlGnayfklgkydeAleyyekA 27 a+ nlG ay++lg++ +A+ey ek FUN_002327-T1 557 AYGNLGIAYQSLGDFRKAIEYHEKH 581 9********************9996 PP == domain 16 score: 19.7 bits; conditional E-value: 1e-06 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A ey ek L++ FUN_002327-T1 597 AYGNLGNAYQSLGDFRKANEYHEKHLKI 624 8***********************9998 PP == domain 17 score: 30.1 bits; conditional E-value: 5.2e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay+ lg++ +A+ey ek Le+ FUN_002327-T1 636 NAYGNLGNAYYLLGDFRKAIEYHEKHLEI 664 69*************************98 PP == domain 18 score: 13.2 bits; conditional E-value: 0.00011 TPR_1 8 GnayfklgkydeAleyyekALel 30 G ay++lg+ +A+ey ek Le+ FUN_002327-T1 682 GSAYRSLGDSRKAIEYHEKHLEI 704 88*******************98 PP == domain 19 score: 25.0 bits; conditional E-value: 2.1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ nlGnay+ lg++ +A+ey ek FUN_002327-T1 716 NAYGNLGNAYQLLGDFRKAIEYHEK 740 69********************998 PP == domain 20 score: 18.9 bits; conditional E-value: 1.8e-06 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ lG ay++lg++ +A+ey ek FUN_002327-T1 756 NAYGSLGRAYQSLGDFRKAIEYHEK 780 59********************998 PP == domain 21 score: 31.1 bits; conditional E-value: 2.5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002327-T1 796 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIA 825 69**************************96 PP == domain 22 score: 8.1 bits; conditional E-value: 0.0047 TPR_1 3 alynlGnayfklgkydeAleyyekALe 29 ++ n+G yf+lg+++ Al + A++ FUN_002327-T1 837 TYHNMGGEYFSLGQFEIALGMFVSAVK 863 699**************9977766665 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 1.5 1.2e+03 14 36 .. 47 62 .. 37 68 .. 0.60 2 ! 14.0 0.1 7e-05 0.052 4 35 .. 77 108 .. 75 108 .. 0.91 3 ! 13.5 0.1 0.0001 0.077 4 35 .. 117 148 .. 115 148 .. 0.91 4 ! 10.3 0.0 0.001 0.77 4 34 .. 157 187 .. 156 188 .. 0.87 5 ! 13.9 0.0 7.9e-05 0.059 5 31 .. 198 224 .. 196 231 .. 0.87 6 ! 12.1 0.0 0.00029 0.22 3 34 .. 236 267 .. 235 268 .. 0.74 7 ! 14.8 0.0 4.1e-05 0.031 3 35 .. 276 308 .. 275 308 .. 0.91 8 ! 11.3 0.0 0.0005 0.38 4 34 .. 317 347 .. 315 348 .. 0.90 9 ! 9.7 0.0 0.0017 1.3 7 34 .. 360 387 .. 358 388 .. 0.88 10 ! 15.1 0.0 3.2e-05 0.024 4 34 .. 397 427 .. 395 428 .. 0.90 11 ! 17.2 0.1 7.3e-06 0.0055 4 35 .. 437 468 .. 435 468 .. 0.91 12 ! 12.8 0.0 0.00017 0.13 3 35 .. 476 508 .. 475 508 .. 0.92 13 ! 10.8 0.0 0.00073 0.55 4 34 .. 517 547 .. 516 548 .. 0.87 14 ! 14.3 0.0 5.6e-05 0.042 3 27 .. 556 580 .. 555 590 .. 0.93 15 ! 17.1 0.0 7.8e-06 0.0059 3 34 .. 596 627 .. 595 628 .. 0.90 16 ! 17.2 0.1 7.3e-06 0.0055 4 35 .. 637 668 .. 635 668 .. 0.91 17 ? 5.7 0.0 0.03 22 3 34 .. 676 707 .. 675 708 .. 0.90 18 ! 15.9 0.1 1.8e-05 0.014 4 34 .. 717 747 .. 715 748 .. 0.91 19 ! 17.2 0.0 7.1e-06 0.0054 4 35 .. 757 788 .. 755 788 .. 0.93 20 ! 20.0 0.0 9.3e-07 0.0007 4 35 .. 797 828 .. 795 828 .. 0.95 21 ! 7.2 0.0 0.0097 7.3 4 30 .. 837 863 .. 836 868 .. 0.91 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 1.5 TPR_10 14 aqgryeeAeelleealairervl 36 + ++++++a++ +e++l FUN_002327-T1 47 S-------LDDFRKAIKYHEKHL 62 4.......555666666666555 PP == domain 2 score: 14.0 bits; conditional E-value: 7e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++ +g+ A e++e+ l+i+ +v FUN_002327-T1 77 AYGNLGNAYQLLGDVRKAIEYHEKHLEIAIEV 108 89**********************99998765 PP == domain 3 score: 13.5 bits; conditional E-value: 0.0001 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++ +g+ A e++e+ l+i+ +v FUN_002327-T1 117 AYRNLGNAYQLLGDVRKAIEYHEKHLEIAIEV 148 899*********************99998765 PP == domain 4 score: 10.3 bits; conditional E-value: 0.001 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na+r++g++ e++e+ l+i+ + FUN_002327-T1 157 TYRNLGNAYRSLGEFRKGIEYHERHLKIAIE 187 799*************999999987777655 PP == domain 5 score: 13.9 bits; conditional E-value: 7.9e-05 TPR_10 5 lnnLanalraqgryeeAeelleealai 31 + nL+ +++++g++ A e++e+ l+i FUN_002327-T1 198 YGNLGITYQSLGDFRKAIEYHEKHLEI 224 78********************98887 PP == domain 6 score: 12.1 bits; conditional E-value: 0.00029 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 +++ nL+na+ ++ ++ A e++e+ l+i+ + FUN_002327-T1 236 TAYGNLGNAYESLSDFRKAIEYHEKHLEIAIE 267 67888888888888888888888887777655 PP == domain 7 score: 14.8 bits; conditional E-value: 4.1e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+na++++g++ A e++e+ l+i+ +v FUN_002327-T1 276 SAYGYLGNAYQSLGDFRKAIEYHEKHLEIAIEV 308 68999********************99998765 PP == domain 8 score: 11.3 bits; conditional E-value: 0.0005 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ n + a+r++g++ A e++e+ l+i+ + FUN_002327-T1 317 AYGNFGIAYRSLGDLRKAIEYHEKHLKIAIE 347 899********************98888766 PP == domain 9 score: 9.7 bits; conditional E-value: 0.0017 TPR_10 7 nLanalraqgryeeAeelleealairer 34 +n+++++g++ A e++e+ l+i+ + FUN_002327-T1 360 SFGNTYQSLGDFRKAIEYHEKHLEIAIE 387 679******************9999876 PP == domain 10 score: 15.1 bits; conditional E-value: 3.2e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na++++g+ A e++e+ l+i+ + FUN_002327-T1 397 AYGNLGNAYQSLGDVRKAIEYHEKHLKIAIE 427 899********************98888766 PP == domain 11 score: 17.2 bits; conditional E-value: 7.3e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++ +g++ A e++e+ l+i+ +v FUN_002327-T1 437 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEV 468 89**********************99998765 PP == domain 12 score: 12.8 bits; conditional E-value: 0.00017 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+ a+r++g++ A e++e+ l+i+ +v FUN_002327-T1 476 SAYGSLGSAYRSLGDLRKAIEYHEKHLEIAIEV 508 6899*********************99998765 PP == domain 13 score: 10.8 bits; conditional E-value: 0.00073 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na+r++g++ e++e+ l+i+ + FUN_002327-T1 517 TYGNLGNAYRSLGEFRKGIEYHERHLKIAIE 547 899*************999999987777665 PP == domain 14 score: 14.3 bits; conditional E-value: 5.6e-05 TPR_10 3 sslnnLanalraqgryeeAeellee 27 s++ nL+ a++++g++ A e++e+ FUN_002327-T1 556 SAYGNLGIAYQSLGDFRKAIEYHEK 580 79*********************97 PP == domain 15 score: 17.1 bits; conditional E-value: 7.8e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 +++ nL+na++++g++ A e++e+ l+i+ + FUN_002327-T1 596 TAYGNLGNAYQSLGDFRKANEYHEKHLKIAIE 627 79**********************98888766 PP == domain 16 score: 17.2 bits; conditional E-value: 7.3e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++ +g++ A e++e+ l+i+ +v FUN_002327-T1 637 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEV 668 89**********************99998765 PP == domain 17 score: 5.7 bits; conditional E-value: 0.03 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ + a+r++g+ A e++e+ l+i+ + FUN_002327-T1 676 SAYGSFGSAYRSLGDSRKAIEYHEKHLEIAIE 707 689999*******************9999876 PP == domain 18 score: 15.9 bits; conditional E-value: 1.8e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na++ +g++ A e++e+ l+i+ + FUN_002327-T1 717 AYGNLGNAYQLLGDFRKAIEYHEKQLEIAIE 747 89*********************99988776 PP == domain 19 score: 17.2 bits; conditional E-value: 7.1e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L++a++++g++ A e++e+ l+i+ +v FUN_002327-T1 757 AYGSLGRAYQSLGDFRKAIEYHEKDLEIAIEV 788 7999***********************98876 PP == domain 20 score: 20.0 bits; conditional E-value: 9.3e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++g++ A e++e+ l+i+++v FUN_002327-T1 797 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 828 89**************************9987 PP == domain 21 score: 7.2 bits; conditional E-value: 0.0097 TPR_10 4 slnnLanalraqgryeeAeelleeala 30 +++n++ ++++g++e A+ ++ a++ FUN_002327-T1 837 TYHNMGGEYFSLGQFEIALGMFVSAVK 863 79*****************99988876 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.1 3.5 2.6e+03 11 26 .. 5 20 .. 4 25 .. 0.75 2 ? 4.7 0.2 0.08 60 2 30 .. 36 64 .. 35 65 .. 0.89 3 ! 15.2 0.2 3.4e-05 0.025 3 30 .. 77 104 .. 75 105 .. 0.90 4 ! 11.3 0.2 0.00062 0.47 3 30 .. 117 144 .. 115 145 .. 0.88 5 ? 7.2 0.0 0.012 9.1 6 26 .. 160 180 .. 156 185 .. 0.84 6 ! 15.6 0.0 2.5e-05 0.019 4 32 .. 198 226 .. 196 228 .. 0.91 7 ! 14.9 0.2 4.1e-05 0.031 3 30 .. 237 264 .. 235 265 .. 0.90 8 ! 13.5 0.3 0.00012 0.088 3 30 .. 277 304 .. 275 305 .. 0.87 9 ! 13.0 0.2 0.00017 0.12 3 30 .. 317 344 .. 315 345 .. 0.89 10 ! 12.3 0.0 0.00029 0.22 4 30 .. 358 384 .. 356 385 .. 0.87 11 ! 17.1 0.2 8.5e-06 0.0064 3 30 .. 397 424 .. 395 425 .. 0.89 12 ! 16.4 0.5 1.4e-05 0.011 3 30 .. 437 464 .. 435 465 .. 0.90 13 ! 17.0 0.1 8.9e-06 0.0067 2 30 .. 476 504 .. 475 505 .. 0.90 14 ! 10.5 0.1 0.0011 0.82 3 26 .. 517 540 .. 516 545 .. 0.86 15 ! 15.5 0.1 2.6e-05 0.02 2 26 .. 556 580 .. 555 587 .. 0.89 16 ! 14.1 0.2 7.8e-05 0.058 3 29 .. 597 623 .. 595 625 .. 0.87 17 ! 16.4 0.5 1.4e-05 0.011 3 30 .. 637 664 .. 635 665 .. 0.90 18 ! 13.3 0.1 0.00014 0.11 3 30 .. 677 704 .. 675 705 .. 0.89 19 ! 19.7 0.4 1.2e-06 0.00091 3 31 .. 717 745 .. 715 745 .. 0.94 20 ! 15.9 0.2 2e-05 0.015 3 26 .. 757 780 .. 755 785 .. 0.88 21 ! 20.5 0.2 6.5e-07 0.00049 3 32 .. 797 826 .. 795 827 .. 0.91 22 ? 3.2 0.0 0.23 1.8e+02 4 20 .. 838 854 .. 837 864 .. 0.87 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 3.5 TPR_8 11 ylklgdyeeAkeyyek 26 y+++g++ +A ey ek FUN_002327-T1 5 YISQGYFRKASEYHEK 20 8888888888888666 PP == domain 2 score: 4.7 bits; conditional E-value: 0.08 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay+nl ++ ++l d+ +A++y ek le+ FUN_002327-T1 36 KAYQNLPYAFQSLDDFRKAIKYHEKHLEI 64 6899999***************9887776 PP == domain 3 score: 15.2 bits; conditional E-value: 3.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y+ lgd +A+ey ek le+ FUN_002327-T1 77 AYGNLGNAYQLLGDVRKAIEYHEKHLEI 104 9********************9987776 PP == domain 4 score: 11.3 bits; conditional E-value: 0.00062 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y+ lgd +A+ey ek le+ FUN_002327-T1 117 AYRNLGNAYQLLGDVRKAIEYHEKHLEI 144 6779*****************9987776 PP == domain 5 score: 7.2 bits; conditional E-value: 0.012 TPR_8 6 nlGliylklgdyeeAkeyyek 26 nlG++y++lg++ + +ey e+ FUN_002327-T1 160 NLGNAYRSLGEFRKGIEYHER 180 9****************9665 PP == domain 6 score: 15.6 bits; conditional E-value: 2.5e-05 TPR_8 4 yynlGliylklgdyeeAkeyyekaleldp 32 y nlG +y++lgd+ +A+ey ek le+++ FUN_002327-T1 198 YGNLGITYQSLGDFRKAIEYHEKHLEIER 226 99******************999999876 PP == domain 7 score: 14.9 bits; conditional E-value: 4.1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++l d+ +A+ey ek le+ FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEYHEKHLEI 264 8********************9887776 PP == domain 8 score: 13.5 bits; conditional E-value: 0.00012 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002327-T1 277 AYGYLGNAYQSLGDFRKAIEYHEKHLEI 304 67779****************9987776 PP == domain 9 score: 13.0 bits; conditional E-value: 0.00017 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay n G +y++lgd+ +A+ey ek l++ FUN_002327-T1 317 AYGNFGIAYRSLGDLRKAIEYHEKHLKI 344 8********************8886665 PP == domain 10 score: 12.3 bits; conditional E-value: 0.00029 TPR_8 4 yynlGliylklgdyeeAkeyyekalel 30 y G++y++lgd+ +A+ey ek le+ FUN_002327-T1 358 YGSFGNTYQSLGDFRKAIEYHEKHLEI 384 7778****************9987776 PP == domain 11 score: 17.1 bits; conditional E-value: 8.5e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd +A+ey ek l++ FUN_002327-T1 397 AYGNLGNAYQSLGDVRKAIEYHEKHLKI 424 9********************8886665 PP == domain 12 score: 16.4 bits; conditional E-value: 1.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y lgd+ +A+ey ek le+ FUN_002327-T1 437 AYGNLGNAYYLLGDFRKAIEYHEKHLEI 464 9********************9987776 PP == domain 13 score: 17.0 bits; conditional E-value: 8.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ey ek le+ FUN_002327-T1 476 SAYGSLGSAYRSLGDLRKAIEYHEKHLEI 504 589*******************9987776 PP == domain 14 score: 10.5 bits; conditional E-value: 0.0011 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 +y nlG++y++lg++ + +ey e+ FUN_002327-T1 517 TYGNLGNAYRSLGEFRKGIEYHER 540 699*****************9665 PP == domain 15 score: 15.5 bits; conditional E-value: 2.6e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay nlG +y++lgd+ +A+ey ek FUN_002327-T1 556 SAYGNLGIAYQSLGDFRKAIEYHEK 580 59*******************9776 PP == domain 16 score: 14.1 bits; conditional E-value: 7.8e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekale 29 ay nlG++y++lgd+ +A ey ek l+ FUN_002327-T1 597 AYGNLGNAYQSLGDFRKANEYHEKHLK 623 8*****************999877665 PP == domain 17 score: 16.4 bits; conditional E-value: 1.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y lgd+ +A+ey ek le+ FUN_002327-T1 637 AYGNLGNAYYLLGDFRKAIEYHEKHLEI 664 9********************9987776 PP == domain 18 score: 13.3 bits; conditional E-value: 0.00014 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay G++y++lgd +A+ey ek le+ FUN_002327-T1 677 AYGSFGSAYRSLGDSRKAIEYHEKHLEI 704 8999*****************9987776 PP == domain 19 score: 19.7 bits; conditional E-value: 1.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay nlG++y+ lgd+ +A+ey ek le++ FUN_002327-T1 717 AYGNLGNAYQLLGDFRKAIEYHEKQLEIA 745 9***********************99985 PP == domain 20 score: 15.9 bits; conditional E-value: 2e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 ay lG++y++lgd+ +A+ey ek FUN_002327-T1 757 AYGSLGRAYQSLGDFRKAIEYHEK 780 89*******************777 PP == domain 21 score: 20.5 bits; conditional E-value: 6.5e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG++y++lgd+ +A+ey ek le+++ FUN_002327-T1 797 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 826 9********************999998875 PP == domain 22 score: 3.2 bits; conditional E-value: 0.23 TPR_8 4 yynlGliylklgdyeeA 20 y+n+G y +lg++e A FUN_002327-T1 838 YHNMGGEYFSLGQFEIA 854 9*************977 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.4 0.0 1e-52 7.7e-50 8 291 .] 1052 1314 .. 1047 1314 .. 0.88 Alignments for each domain: == domain 1 score: 170.4 bits; conditional E-value: 1e-52 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ +Lviv dgaL +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ + k FUN_002327-T1 1052 YDAVIGPIEDLL-GPEDDELVIVSDGALCFIPWAAVIESIR---------IRIVPSLKSyqlISSVPEGYHKKTGA--LLVGNPCLEQ----LK 1129 899****99997.77777*****************988863.........55556654422266666666666666..******9774....35 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 + lp +++E++++a++l+ +l+g++at+ ++++ + ++++++H+a+Hg + + ++L++ n + ed L++++++ FUN_002327-T1 1130 NPLHALPCAQKEVEMIAAILKN---TPLVGKQATKAEVMKRM-SSVGLIHIAAHGDVV-----TGQIALSP-NPGwtqfpkeEDYILKMSDVQA 1213 55699***************77...8***************9.***************.....89999975.4445889999************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002327-T1 1214 ANLR-ARLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLMALWAIDDEATMEFMKRFYQHLKEGKTASAAVHQSMKSLRESEE----FSE 1302 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002327-T1 1303 MWYWAPFQLIGD 1314 ***********7 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.1 4 3e+03 20 31 .. 47 58 .. 43 61 .. 0.69 2 ! 12.0 0.3 0.00033 0.25 3 23 .. 77 97 .. 75 104 .. 0.93 3 ! 13.6 0.4 0.00011 0.083 2 23 .. 116 137 .. 115 145 .. 0.92 4 ! 8.2 0.1 0.0058 4.3 4 23 .. 158 177 .. 156 184 .. 0.92 5 ! 10.4 0.0 0.0011 0.83 3 23 .. 197 217 .. 195 226 .. 0.90 6 ! 9.7 0.1 0.0019 1.5 3 23 .. 237 257 .. 235 264 .. 0.90 7 ! 13.6 0.4 0.00011 0.08 3 23 .. 277 297 .. 275 305 .. 0.92 8 ? 7.3 0.1 0.012 8.7 3 23 .. 317 337 .. 315 344 .. 0.90 9 ? 5.8 0.0 0.033 25 8 23 .. 362 377 .. 357 384 .. 0.93 10 ! 12.1 0.2 0.00031 0.24 3 23 .. 397 417 .. 395 424 .. 0.93 11 ! 16.5 0.8 1.2e-05 0.0093 3 23 .. 437 457 .. 435 465 .. 0.92 12 ! 8.4 0.1 0.0048 3.6 3 23 .. 477 497 .. 475 505 .. 0.90 13 ? 6.8 0.1 0.017 12 4 23 .. 518 537 .. 516 543 .. 0.91 14 ! 12.8 0.1 0.0002 0.15 3 23 .. 557 577 .. 555 580 .. 0.93 15 ! 11.1 0.2 0.00066 0.5 3 23 .. 597 617 .. 595 624 .. 0.92 16 ! 16.5 0.8 1.2e-05 0.0093 3 23 .. 637 657 .. 635 665 .. 0.92 17 ? 1.9 0.1 0.59 4.5e+02 8 23 .. 682 697 .. 677 704 .. 0.91 18 ! 14.3 0.4 6.1e-05 0.046 3 23 .. 717 737 .. 715 744 .. 0.93 19 ! 11.9 0.2 0.00037 0.28 3 28 .. 757 782 .. 755 786 .. 0.84 20 ! 14.7 0.4 4.8e-05 0.036 3 23 .. 797 817 .. 795 827 .. 0.89 21 ? 4.0 0.0 0.12 94 4 29 .. 838 863 .. 836 868 .. 0.80 22 ? -1.2 0.0 5.7 4.3e+03 10 26 .. 896 912 .. 895 915 .. 0.84 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 4 TPR_2 20 AleayekAleld 31 l++++kA+++ FUN_002327-T1 47 SLDDFRKAIKYH 58 567788888765 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00033 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd +A+e+ FUN_002327-T1 77 AYGNLGNAYQLLGDVRKAIEY 97 899****************98 PP == domain 3 score: 13.6 bits; conditional E-value: 0.00011 TPR_2 2 ealynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd +A+e+ FUN_002327-T1 116 NAYRNLGNAYQLLGDVRKAIEY 137 58******************98 PP == domain 4 score: 8.2 bits; conditional E-value: 0.0058 TPR_2 4 lynlGlayyklgdyeeAlea 23 + nlG+ay+ lg++ + +e+ FUN_002327-T1 158 YRNLGNAYRSLGEFRKGIEY 177 89*************99987 PP == domain 5 score: 10.4 bits; conditional E-value: 0.0011 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nlG y lgd+ +A+e+ FUN_002327-T1 197 GYGNLGITYQSLGDFRKAIEY 217 5789***************98 PP == domain 6 score: 9.7 bits; conditional E-value: 0.0019 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ l d+ +A+e+ FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEY 257 7899**************998 PP == domain 7 score: 13.6 bits; conditional E-value: 0.00011 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ +lG+ay lgd+ +A+e+ FUN_002327-T1 277 AYGYLGNAYQSLGDFRKAIEY 297 899****************98 PP == domain 8 score: 7.3 bits; conditional E-value: 0.012 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ n G ay+ lgd+ +A+e+ FUN_002327-T1 317 AYGNFGIAYRSLGDLRKAIEY 337 77888**************98 PP == domain 9 score: 5.8 bits; conditional E-value: 0.033 TPR_2 8 GlayyklgdyeeAlea 23 G+ y lgd+ +A+e+ FUN_002327-T1 362 GNTYQSLGDFRKAIEY 377 899***********98 PP == domain 10 score: 12.1 bits; conditional E-value: 0.00031 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd +A+e+ FUN_002327-T1 397 AYGNLGNAYQSLGDVRKAIEY 417 899****************98 PP == domain 11 score: 16.5 bits; conditional E-value: 1.2e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ayy lgd+ +A+e+ FUN_002327-T1 437 AYGNLGNAYYLLGDFRKAIEY 457 899****************98 PP == domain 12 score: 8.4 bits; conditional E-value: 0.0048 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG ay+ lgd+ +A+e+ FUN_002327-T1 477 AYGSLGSAYRSLGDLRKAIEY 497 67789**************98 PP == domain 13 score: 6.8 bits; conditional E-value: 0.017 TPR_2 4 lynlGlayyklgdyeeAlea 23 + nlG+ay+ lg++ + +e+ FUN_002327-T1 518 YGNLGNAYRSLGEFRKGIEY 537 779************99987 PP == domain 14 score: 12.8 bits; conditional E-value: 0.0002 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+ +A+e+ FUN_002327-T1 557 AYGNLGIAYQSLGDFRKAIEY 577 899****************98 PP == domain 15 score: 11.1 bits; conditional E-value: 0.00066 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A e+ FUN_002327-T1 597 AYGNLGNAYQSLGDFRKANEY 617 899***************887 PP == domain 16 score: 16.5 bits; conditional E-value: 1.2e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ayy lgd+ +A+e+ FUN_002327-T1 637 AYGNLGNAYYLLGDFRKAIEY 657 899****************98 PP == domain 17 score: 1.9 bits; conditional E-value: 0.59 TPR_2 8 GlayyklgdyeeAlea 23 G ay+ lgd +A+e+ FUN_002327-T1 682 GSAYRSLGDSRKAIEY 697 789***********98 PP == domain 18 score: 14.3 bits; conditional E-value: 6.1e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002327-T1 717 AYGNLGNAYQLLGDFRKAIEY 737 899****************98 PP == domain 19 score: 11.9 bits; conditional E-value: 0.00037 TPR_2 3 alynlGlayyklgdyeeAleayekAl 28 a+ lG+ay lgd+ +A+e+ ek l FUN_002327-T1 757 AYGSLGRAYQSLGDFRKAIEYHEKDL 782 7888****************966655 PP == domain 20 score: 14.7 bits; conditional E-value: 4.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002327-T1 797 AYGNLGNAYQSLGDFRKAIEY 817 899*****************9 PP == domain 21 score: 4.0 bits; conditional E-value: 0.12 TPR_2 4 lynlGlayyklgdyeeAleayekAle 29 ++n+G y+ lg++e Al + A++ FUN_002327-T1 838 YHNMGGEYFSLGQFEIALGMFVSAVK 863 89999999999999999877766665 PP == domain 22 score: -1.2 bits; conditional E-value: 5.7 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002327-T1 896 LLLRIGKTDEALFAADQ 912 68899*******98776 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.9 0.1 0.0082 6.1 14 34 .] 76 96 .. 74 96 .. 0.92 2 ? 6.8 0.1 0.017 13 14 34 .] 116 136 .. 114 136 .. 0.92 3 ? 1.1 0.0 1.2 8.7e+02 16 31 .. 158 173 .. 155 176 .. 0.84 4 ? 5.8 0.0 0.038 28 16 34 .] 198 216 .. 195 216 .. 0.91 5 ? 4.1 0.0 0.13 96 15 34 .] 237 256 .. 235 256 .. 0.92 6 ? 5.7 0.1 0.039 30 15 34 .] 277 296 .. 274 296 .. 0.92 7 ? 5.3 0.0 0.054 40 14 34 .] 316 336 .. 314 336 .. 0.92 8 ? 1.4 0.0 0.92 6.9e+02 15 34 .] 357 376 .. 354 376 .. 0.87 9 ! 7.7 0.1 0.0093 7 14 34 .] 396 416 .. 394 416 .. 0.92 10 ? 6.8 0.2 0.018 13 14 34 .] 436 456 .. 434 456 .. 0.92 11 ? 3.4 0.0 0.22 1.7e+02 15 34 .] 477 496 .. 474 496 .. 0.91 12 ? 2.0 0.0 0.6 4.5e+02 15 31 .. 517 533 .. 515 536 .. 0.84 13 ? 6.9 0.0 0.016 12 14 34 .] 556 576 .. 554 576 .. 0.92 14 ? 4.6 0.1 0.09 68 15 32 .. 597 614 .. 595 614 .. 0.92 15 ? 6.8 0.2 0.018 13 14 34 .] 636 656 .. 634 656 .. 0.92 16 ? 1.0 0.0 1.3 9.9e+02 15 34 .] 677 696 .. 675 696 .. 0.90 17 ! 8.5 0.1 0.005 3.7 14 34 .] 716 736 .. 713 736 .. 0.92 18 ? 5.2 0.0 0.058 43 14 34 .] 756 776 .. 753 776 .. 0.92 19 ! 8.3 0.1 0.006 4.5 14 34 .] 796 816 .. 794 816 .. 0.93 Alignments for each domain: == domain 1 score: 7.9 bits; conditional E-value: 0.0082 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G+ +A++ FUN_002327-T1 76 NAYGNLGNAYQLLGDVRKAIE 96 79***************9985 PP == domain 2 score: 6.8 bits; conditional E-value: 0.017 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G+ +A++ FUN_002327-T1 116 NAYRNLGNAYQLLGDVRKAIE 136 79***************9985 PP == domain 3 score: 1.1 bits; conditional E-value: 1.2 TPR_17 16 yynLArlllnnGqlee 31 y nL+++++ +G++ + FUN_002327-T1 158 YRNLGNAYRSLGEFRK 173 88*********99866 PP == domain 4 score: 5.8 bits; conditional E-value: 0.038 TPR_17 16 yynLArlllnnGqleeAlq 34 y nL+++++ +G++ +A++ FUN_002327-T1 198 YGNLGITYQSLGDFRKAIE 216 99**************985 PP == domain 5 score: 4.1 bits; conditional E-value: 0.13 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ + ++ +A++ FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIE 256 89*************99985 PP == domain 6 score: 5.7 bits; conditional E-value: 0.039 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay +L+++++ +G++ +A++ FUN_002327-T1 277 AYGYLGNAYQSLGDFRKAIE 296 89***************985 PP == domain 7 score: 5.3 bits; conditional E-value: 0.054 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay n +++++ +G+l +A++ FUN_002327-T1 316 NAYGNFGIAYRSLGDLRKAIE 336 79****************985 PP == domain 8 score: 1.4 bits; conditional E-value: 0.92 TPR_17 15 ayynLArlllnnGqleeAlq 34 y +++++ +G++ +A++ FUN_002327-T1 357 GYGSFGNTYQSLGDFRKAIE 376 57889************985 PP == domain 9 score: 7.7 bits; conditional E-value: 0.0093 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G+ +A++ FUN_002327-T1 396 NAYGNLGNAYQSLGDVRKAIE 416 79***************9985 PP == domain 10 score: 6.8 bits; conditional E-value: 0.018 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL++++ +G++ +A++ FUN_002327-T1 436 NAYGNLGNAYYLLGDFRKAIE 456 79****************985 PP == domain 11 score: 3.4 bits; conditional E-value: 0.22 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+ +++ +G+l +A++ FUN_002327-T1 477 AYGSLGSAYRSLGDLRKAIE 496 899**************985 PP == domain 12 score: 2.0 bits; conditional E-value: 0.6 TPR_17 15 ayynLArlllnnGqlee 31 y nL+++++ +G++ + FUN_002327-T1 517 TYGNLGNAYRSLGEFRK 533 599*********99866 PP == domain 13 score: 6.9 bits; conditional E-value: 0.016 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002327-T1 556 SAYGNLGIAYQSLGDFRKAIE 576 59****************985 PP == domain 14 score: 4.6 bits; conditional E-value: 0.09 TPR_17 15 ayynLArlllnnGqleeA 32 ay nL+++++ +G++ +A FUN_002327-T1 597 AYGNLGNAYQSLGDFRKA 614 89************9887 PP == domain 15 score: 6.8 bits; conditional E-value: 0.018 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL++++ +G++ +A++ FUN_002327-T1 636 NAYGNLGNAYYLLGDFRKAIE 656 79****************985 PP == domain 16 score: 1.0 bits; conditional E-value: 1.3 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay + +++ +G++ +A++ FUN_002327-T1 677 AYGSFGSAYRSLGDSRKAIE 696 89999************985 PP == domain 17 score: 8.5 bits; conditional E-value: 0.005 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002327-T1 716 NAYGNLGNAYQLLGDFRKAIE 736 79****************985 PP == domain 18 score: 5.2 bits; conditional E-value: 0.058 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+r+++ +G++ +A++ FUN_002327-T1 756 NAYGSLGRAYQSLGDFRKAIE 776 79****************985 PP == domain 19 score: 8.3 bits; conditional E-value: 0.006 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002327-T1 796 NAYGNLGNAYQSLGDFRKAIE 816 79****************985 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.1 0.32 2.4e+02 6 29 .. 80 103 .. 76 105 .. 0.86 2 ? 6.0 0.1 0.048 36 2 29 .. 116 143 .. 115 145 .. 0.90 3 ? 5.3 0.0 0.081 61 4 29 .. 158 183 .. 156 187 .. 0.90 4 ? 2.3 0.0 0.73 5.5e+02 7 30 .. 201 224 .. 198 228 .. 0.85 5 ? 2.2 0.0 0.78 5.9e+02 7 29 .. 241 263 .. 236 265 .. 0.87 6 ? 6.5 0.1 0.032 24 4 29 .. 278 303 .. 276 305 .. 0.87 7 ? 3.1 0.0 0.42 3.2e+02 9 29 .. 323 343 .. 317 346 .. 0.88 8 ? 1.9 0.0 0.98 7.4e+02 9 29 .. 363 383 .. 359 385 .. 0.87 9 ? 4.4 0.0 0.16 1.2e+02 6 29 .. 400 423 .. 396 425 .. 0.87 10 ? 5.6 0.1 0.066 49 6 29 .. 440 463 .. 436 465 .. 0.86 11 ? 5.9 0.1 0.052 39 6 29 .. 480 503 .. 476 505 .. 0.87 12 ? 3.6 0.0 0.27 2.1e+02 7 29 .. 521 543 .. 517 546 .. 0.91 13 ? 2.2 0.0 0.79 6e+02 7 26 .. 561 580 .. 556 587 .. 0.86 14 ? 2.6 0.0 0.61 4.6e+02 7 29 .. 601 623 .. 596 625 .. 0.87 15 ? 5.6 0.1 0.066 49 6 29 .. 640 663 .. 636 665 .. 0.86 16 ? 2.0 0.0 0.91 6.9e+02 8 29 .. 682 703 .. 677 705 .. 0.88 17 ? 4.4 0.1 0.16 1.2e+02 6 29 .. 720 743 .. 716 746 .. 0.85 18 ? 4.3 0.0 0.16 1.2e+02 5 25 .. 759 779 .. 756 780 .. 0.85 19 ? 6.4 0.0 0.034 26 6 30 .. 800 824 .. 796 830 .. 0.86 20 ? 2.1 0.0 0.85 6.4e+02 4 27 .. 845 868 .. 841 880 .. 0.75 21 ? 3.2 0.1 0.39 2.9e+02 9 39 .. 895 926 .. 895 930 .. 0.71 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.32 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd +A+e+ e+ l+ FUN_002327-T1 80 NLGNAYQLLGDVRKAIEYHEKHLE 103 689***************998876 PP == domain 2 score: 6.0 bits; conditional E-value: 0.048 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a++ l++a+ lGd +A+e+ e+ l+ FUN_002327-T1 116 NAYRNLGNAYQLLGDVRKAIEYHEKHLE 143 68999*****************998876 PP == domain 3 score: 5.3 bits; conditional E-value: 0.081 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ l++a++ lG++ + +e+ er l+ FUN_002327-T1 158 YRNLGNAYRSLGEFRKGIEYHERHLK 183 6789******************9987 PP == domain 4 score: 2.3 bits; conditional E-value: 0.73 TPR_14 7 larallalGdpdeAlelleralal 30 l+ ++ lGd+ +A+e+ e+ l+ FUN_002327-T1 201 LGITYQSLGDFRKAIEYHEKHLEI 224 5667999**********9998875 PP == domain 5 score: 2.2 bits; conditional E-value: 0.78 TPR_14 7 larallalGdpdeAlellerala 29 l++a++ l d+ +A+e+ e+ l+ FUN_002327-T1 241 LGNAYESLSDFRKAIEYHEKHLE 263 899**************998876 PP == domain 6 score: 6.5 bits; conditional E-value: 0.032 TPR_14 4 wlalarallalGdpdeAlellerala 29 + +l++a+ lGd+ +A+e+ e+ l+ FUN_002327-T1 278 YGYLGNAYQSLGDFRKAIEYHEKHLE 303 5589****************998876 PP == domain 7 score: 3.1 bits; conditional E-value: 0.42 TPR_14 9 rallalGdpdeAlellerala 29 a++ lGd+ +A+e+ e+ l+ FUN_002327-T1 323 IAYRSLGDLRKAIEYHEKHLK 343 589************999876 PP == domain 8 score: 1.9 bits; conditional E-value: 0.98 TPR_14 9 rallalGdpdeAlellerala 29 +++ lGd+ +A+e+ e+ l+ FUN_002327-T1 363 NTYQSLGDFRKAIEYHEKHLE 383 78999**********998876 PP == domain 9 score: 4.4 bits; conditional E-value: 0.16 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd +A+e+ e+ l+ FUN_002327-T1 400 NLGNAYQSLGDVRKAIEYHEKHLK 423 689***************999876 PP == domain 10 score: 5.6 bits; conditional E-value: 0.066 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002327-T1 440 NLGNAYYLLGDFRKAIEYHEKHLE 463 689***************998876 PP == domain 11 score: 5.9 bits; conditional E-value: 0.052 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a++ lGd+ +A+e+ e+ l+ FUN_002327-T1 480 SLGSAYRSLGDLRKAIEYHEKHLE 503 6899**************998876 PP == domain 12 score: 3.6 bits; conditional E-value: 0.27 TPR_14 7 larallalGdpdeAlellerala 29 l++a++ lG++ + +e+ er l+ FUN_002327-T1 521 LGNAYRSLGEFRKGIEYHERHLK 543 899****************9887 PP == domain 13 score: 2.2 bits; conditional E-value: 0.79 TPR_14 7 larallalGdpdeAleller 26 l+ a+ lGd+ +A+e+ e+ FUN_002327-T1 561 LGIAYQSLGDFRKAIEYHEK 580 7889************9876 PP == domain 14 score: 2.6 bits; conditional E-value: 0.61 TPR_14 7 larallalGdpdeAlellerala 29 l++a+ lGd+ +A e+ e+ l+ FUN_002327-T1 601 LGNAYQSLGDFRKANEYHEKHLK 623 899*************9998876 PP == domain 15 score: 5.6 bits; conditional E-value: 0.066 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002327-T1 640 NLGNAYYLLGDFRKAIEYHEKHLE 663 689***************998876 PP == domain 16 score: 2.0 bits; conditional E-value: 0.91 TPR_14 8 arallalGdpdeAlellerala 29 + a++ lGd +A+e+ e+ l+ FUN_002327-T1 682 GSAYRSLGDSRKAIEYHEKHLE 703 679*************998876 PP == domain 17 score: 4.4 bits; conditional E-value: 0.16 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002327-T1 720 NLGNAYQLLGDFRKAIEYHEKQLE 743 689**************9998765 PP == domain 18 score: 4.3 bits; conditional E-value: 0.16 TPR_14 5 lalarallalGdpdeAlelle 25 l+ra+ lGd+ +A+e+ e FUN_002327-T1 759 GSLGRAYQSLGDFRKAIEYHE 779 5799*************9866 PP == domain 19 score: 6.4 bits; conditional E-value: 0.034 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002327-T1 800 NLGNAYQSLGDFRKAIEYHEKHLEI 824 689***************9999886 PP == domain 20 score: 2.1 bits; conditional E-value: 0.85 TPR_14 4 wlalarallalGdpdeAlellera 27 + l++++ alG + A+++++ + FUN_002327-T1 845 YFSLGQFEIALGMFVSAVKVFNTL 868 567888888888888888888766 PP == domain 21 score: 3.2 bits; conditional E-value: 0.39 TPR_14 9 rallalGdpdeAlelleralald.Pddpeawl 39 r+ll+ G++deAl +++++ a+ d+ +++ FUN_002327-T1 895 RLLLRIGKTDEALFAADQGRAQTlSDNLLIQY 926 5899**************97763133344444 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.0 0.0028 2.1 15 113 .. 89 188 .. 83 199 .. 0.89 2 ! 9.0 0.0 0.0014 1.1 11 158 .. 205 352 .. 201 385 .. 0.79 3 ! 14.8 0.0 2.4e-05 0.018 11 152 .. 365 505 .. 361 514 .. 0.80 4 ! 12.0 0.0 0.00018 0.13 13 115 .. 407 510 .. 402 552 .. 0.86 5 ! 11.0 0.0 0.00035 0.26 40 152 .. 555 665 .. 522 678 .. 0.84 6 ! 11.2 0.0 0.0003 0.23 40 155 .. 715 828 .. 682 838 .. 0.88 7 ? 1.5 0.0 0.27 2e+02 13 68 .. 807 863 .. 803 887 .. 0.77 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0028 TPR_MalT 15 geaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 g++ +a+e+ ++ L++ e + + + a+ +lG a++l+gd+ +A + ++ ++a + ++ +++ +++ +r G++++ +e ++ l+ FUN_002327-T1 89 GDVRKAIEYHEKHLEIAIEVGHRVGeGNAYRNLGNAYQLLGDVRKAIEYHEKHLEIAIEVGDRVGEGGTYRNLGNAYRSLGEFRKGIEYHERHLKI 184 778888888888888888888887779999**************9999999999999999999999****************************99 PP TPR_MalT 110 aqes 113 a e FUN_002327-T1 185 AIEV 188 9875 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0014 TPR_MalT 11 avsqgeaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyq 104 + s g++ +a+e+ ++ L++ +e d+ ++a+ +lG a+ + d+ +A + ++ ++a + ++ a+ +++ ++ G++++A+e + FUN_002327-T1 205 YQSLGDFRKAIEYHEKHLEIEREigDR-TGEGTAYGNLGNAYESLSDFRKAIEYHEKHLEIAIEVGNRVGEGSAYGYLGNAYQSLGDFRKAIEYHE 299 566788888888888888888764233.45578889*************99999999999999999999999999999999*************** PP TPR_MalT 105 qalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epa 158 + l+ a e + + g ++ + ++ +dL +A ++ ++ ++++ ++ +++ FUN_002327-T1 300 KHLEIAIEVGNRV--GQGNAYGNFGIAYRSLGDLRKAIEYHEKHLKIAIEVgDRD 352 *****99999885..8888888999999999999999888888888776654445 PP == domain 3 score: 14.8 bits; conditional E-value: 2.4e-05 TPR_MalT 11 avsqgeaeeaeelAreALal.lpeddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 + s g++ +a+e+ ++ L++ ++ ++ ++ a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ + G++++A+e ++ FUN_002327-T1 365 YQSLGDFRKAIEYHEKHLEIaIEVGNWVGKGNAYGNLGNAYQSLGDVRKAIEYHEKHLKIAIEVGHRVGEGNAYGNLGNAYYLLGDFRKAIEYHEK 460 566788888999999999873566788889999999999999999988888888888888887777777888999999999999999999999999 PP TPR_MalT 106 alqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 l+ a e + + g ++ +l+ ++ +dL +A ++ ++ ++++ FUN_002327-T1 461 HLEIAIEVGDRV--GEGSAYGSLGSAYRSLGDLRKAIEYHEKHLEIA 505 999999998885..777888899999999999999987777766665 PP == domain 4 score: 12.0 bits; conditional E-value: 0.00018 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + + a+ +lG a+ l+gd+ +A + ++ ++a + ++ a+ +++ +r G+L++A+e ++ l FUN_002327-T1 407 SLGDVRKAIEYHEKHLKIAIEVGHRVGeGNAYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGSLGSAYRSLGDLRKAIEYHEKHL 502 678999999999999999999888887799*******************999999999999999988999************************99 PP TPR_MalT 108 qlaqeskl 115 + a e + FUN_002327-T1 503 EIAIEVGN 510 99988665 PP == domain 5 score: 11.0 bits; conditional E-value: 0.00035 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 ++a+ +lG a++ +gd+ +A + ++ +++ r+ ++ + a+ +++ ++ G++++A e ++ l+ a e + + g ++ l++ +y FUN_002327-T1 555 GSAYGNLGIAYQSLGDFRKAIEYHEKHSEIEREVGDRTGEGTAYGNLGNAYQSLGDFRKANEYHEKHLKIAIEVGDRV--GEGNAYGNLGNAYYLL 648 67889*****************99999999999999999999*******************************99995..8889999999999999 PP TPR_MalT 136 ndLeeAeqhlqqgiqlg 152 +d+ +A ++ ++ ++++ FUN_002327-T1 649 GDFRKAIEYHEKHLEIA 665 99999988777666654 PP == domain 6 score: 11.2 bits; conditional E-value: 0.0003 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 + a+ +lG a++l+gd+ +A + ++ ++a + ++ + a+ +++ ++ G++++A+e ++ l+ a e + + + g ++ l++ + FUN_002327-T1 715 GNAYGNLGNAYQLLGDFRKAIEYHEKQLEIAIEVGDRDGEGNAYGSLGRAYQSLGDFRKAIEYHEKDLEIAIEVGNR--FGEGNAYGNLGNAYQSL 808 678999****************99999999999999999999******************************99988..79999999999999999 PP TPR_MalT 136 ndLeeAeqhlqqgiqlgrql 155 +d+ +A ++ ++ +++++++ FUN_002327-T1 809 GDFRKAIEYHEKHLEIAKEV 828 99999999999999998876 PP == domain 7 score: 1.5 bits; conditional E-value: 0.27 TPR_MalT 13 sqgeaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaea 68 s g++ +a+e+ ++ L++ +e d++ + ++++ ++G ++ +g++e Al ++ +a + FUN_002327-T1 807 SLGDFRKAIEYHEKHLEIAKEvgDRVGE-GITYHNMGGEYFSLGQFEIALGMFVSAVK 863 5688888888888888888874355444.55568888899999999999998877765 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.1 8e+02 38 77 .. 33 69 .. 7 72 .. 0.69 2 ? 1.4 0.1 0.63 4.7e+02 39 76 .. 71 108 .. 49 111 .. 0.76 3 ? -0.2 0.0 2 1.5e+03 46 77 .. 121 149 .. 112 152 .. 0.77 4 ? 2.2 0.0 0.35 2.7e+02 43 78 .. 158 190 .. 150 192 .. 0.81 5 ? 4.5 0.1 0.069 52 49 78 .. 201 230 .. 190 232 .. 0.84 6 ? 2.3 0.0 0.33 2.5e+02 45 76 .. 237 268 .. 229 271 .. 0.85 7 ! 8.7 0.0 0.0035 2.6 46 76 .. 278 308 .. 268 311 .. 0.90 8 ? 0.4 0.0 1.3 9.6e+02 51 78 .. 323 350 .. 314 352 .. 0.85 9 ? 3.4 0.1 0.16 1.2e+02 38 76 .. 350 388 .. 328 391 .. 0.75 10 ? 1.9 0.0 0.46 3.5e+02 46 76 .. 398 428 .. 392 431 .. 0.88 11 ? 5.3 0.2 0.04 30 39 78 .. 431 470 .. 405 472 .. 0.75 12 ? 2.2 0.0 0.36 2.7e+02 46 76 .. 478 508 .. 469 511 .. 0.87 13 ? 2.8 0.0 0.23 1.7e+02 47 78 .. 519 550 .. 515 552 .. 0.90 14 ? 3.0 0.0 0.2 1.5e+02 46 78 .. 558 590 .. 550 592 .. 0.85 15 ? 3.8 0.0 0.12 87 35 78 .. 587 630 .. 581 632 .. 0.86 16 ? 4.5 0.0 0.068 51 45 77 .. 637 669 .. 627 671 .. 0.85 17 ? -1.1 0.0 3.7 2.8e+03 50 76 .. 682 708 .. 677 712 .. 0.85 18 ! 10.9 0.1 0.00072 0.54 37 78 .. 709 750 .. 689 752 .. 0.84 19 ! 7.6 0.0 0.0075 5.6 38 76 .. 750 788 .. 747 791 .. 0.88 20 ! 8.7 0.0 0.0035 2.6 46 78 .. 798 830 .. 788 831 .. 0.89 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.1 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeele 77 + e ++ l y a + ++ a+++ + l+ia e+ FUN_002327-T1 33 REEKAYQNLPY---AFQSLDDFRKAIKYHEKHLEIAIEVG 69 44555555555...5556778999****999999999876 PP == domain 2 score: 1.4 bits; conditional E-value: 0.63 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaeel 76 r + + G l +a+ +G + a+e+ + l+ia e+ FUN_002327-T1 71 RVGEGNAYGNLGNAYQLLGDVRKAIEYHEKHLEIAIEV 108 44555677889999999999999999999999999886 PP == domain 3 score: -0.2 bits; conditional E-value: 2 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 lG +a+ +G + a+e+ + l+ia e+ FUN_002327-T1 121 LG---NAYQLLGDVRKAIEYHEKHLEIAIEVG 149 44...45556899999*******999999876 PP == domain 4 score: 2.2 bits; conditional E-value: 0.35 Rapsyn_N 43 frllGylitahsemGkykealefslaqlniaeeled 78 +r lG +a+ +G ++ +e+ l ia e+ d FUN_002327-T1 158 YRNLG---NAYRSLGEFRKGIEYHERHLKIAIEVGD 190 55555...57789*****************999865 PP == domain 5 score: 4.5 bits; conditional E-value: 0.069 Rapsyn_N 49 litahsemGkykealefslaqlniaeeled 78 l ++ +G ++ a+e+ + l+i +e+ d FUN_002327-T1 201 LGITYQSLGDFRKAIEYHEKHLEIEREIGD 230 55556789*******************976 PP == domain 6 score: 2.3 bits; conditional E-value: 0.33 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeel 76 G l +a+ + ++ a+e+ + l+ia e+ FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEYHEKHLEIAIEV 268 56889999999*****************9886 PP == domain 7 score: 8.7 bits; conditional E-value: 0.0035 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 Gyl +a+ +G ++ a+e+ + l+ia e+ FUN_002327-T1 278 YGYLGNAYQSLGDFRKAIEYHEKHLEIAIEV 308 69*************************9886 PP == domain 8 score: 0.4 bits; conditional E-value: 1.3 Rapsyn_N 51 tahsemGkykealefslaqlniaeeled 78 a+ +G + a+e+ + l ia e+ d FUN_002327-T1 323 IAYRSLGDLRKAIEYHEKHLKIAIEVGD 350 578899*****************99877 PP == domain 9 score: 3.4 bits; conditional E-value: 0.16 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeel 76 dr++ + G + +++ +G ++ a+e+ + l+ia e+ FUN_002327-T1 350 DRDGEGNGYGSFGNTYQSLGDFRKAIEYHEKHLEIAIEV 388 5555556667777788899***************99886 PP == domain 10 score: 1.9 bits; conditional E-value: 0.46 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G + a+e+ + l ia e+ FUN_002327-T1 398 YGNLGNAYQSLGDVRKAIEYHEKHLKIAIEV 428 6889999*******************99886 PP == domain 11 score: 5.3 bits; conditional E-value: 0.04 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaeeled 78 r + + G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002327-T1 431 RVGEGNAYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEVGD 470 4455567899999**********************99865 PP == domain 12 score: 2.2 bits; conditional E-value: 0.36 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G + a+e+ + l+ia e+ FUN_002327-T1 478 YGSLGSAYRSLGDLRKAIEYHEKHLEIAIEV 508 6889999********************9886 PP == domain 13 score: 2.8 bits; conditional E-value: 0.23 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ +e+ l ia e+ d FUN_002327-T1 519 GNLGNAYRSLGEFRKGIEYHERHLKIAIEVGD 550 7888999*******************999865 PP == domain 14 score: 3.0 bits; conditional E-value: 0.2 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l a+ +G ++ a+e+ + +i +e+ d FUN_002327-T1 558 YGNLGIAYQSLGDFRKAIEYHEKHSEIEREVGD 590 5778889999***********999999999865 PP == domain 15 score: 3.8 bits; conditional E-value: 0.12 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 + dr + G l +a+ +G ++ a e+ + l ia e+ d FUN_002327-T1 587 EVGDRTGEGTAYGNLGNAYQSLGDFRKANEYHEKHLKIAIEVGD 630 56677777788999************************999865 PP == domain 16 score: 4.5 bits; conditional E-value: 0.068 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002327-T1 637 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAIEVG 669 56889999999******************9976 PP == domain 17 score: -1.1 bits; conditional E-value: 3.7 Rapsyn_N 50 itahsemGkykealefslaqlniaeel 76 a+ +G + a+e+ + l+ia e+ FUN_002327-T1 682 GSAYRSLGDSRKAIEYHEKHLEIAIEV 708 5688899****************9886 PP == domain 18 score: 10.9 bits; conditional E-value: 0.00072 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeeled 78 +re+ + G l +a+ +G ++ a+e+ +ql+ia e+ d FUN_002327-T1 709 GKREGEGNAYGNLGNAYQLLGDFRKAIEYHEKQLEIAIEVGD 750 57888888999**************************99877 PP == domain 19 score: 7.6 bits; conditional E-value: 0.0075 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeel 76 dr++ + G l +a+ +G ++ a+e+ + l+ia e+ FUN_002327-T1 750 DRDGEGNAYGSLGRAYQSLGDFRKAIEYHEKDLEIAIEV 788 67777788899************************9886 PP == domain 20 score: 8.7 bits; conditional E-value: 0.0035 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002327-T1 798 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVGD 830 688999************************865 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.87 6.5e+02 14 31 .. 85 102 .. 81 106 .. 0.90 2 ? 1.4 0.0 0.67 5.1e+02 13 31 .. 124 142 .. 118 145 .. 0.88 3 ? 1.1 0.0 0.8 6e+02 14 31 .. 165 182 .. 159 185 .. 0.86 4 ? 3.3 0.0 0.16 1.2e+02 12 31 .. 203 222 .. 199 225 .. 0.88 5 ? 1.2 0.0 0.77 5.8e+02 14 31 .. 285 302 .. 283 305 .. 0.89 6 ? 2.7 0.0 0.25 1.9e+02 12 31 .. 323 342 .. 320 345 .. 0.90 7 ? 1.0 0.0 0.89 6.7e+02 14 31 .. 365 382 .. 364 385 .. 0.88 8 ? -0.1 0.0 1.9 1.4e+03 14 31 .. 405 422 .. 403 425 .. 0.88 9 ? 2.3 0.0 0.34 2.5e+02 14 31 .. 445 462 .. 440 465 .. 0.90 10 ? 1.1 0.0 0.81 6.1e+02 14 31 .. 485 502 .. 483 505 .. 0.88 11 ? 0.8 0.0 1 7.6e+02 14 31 .. 525 542 .. 523 545 .. 0.87 12 ? 1.8 0.0 0.48 3.6e+02 12 29 .. 563 580 .. 559 582 .. 0.88 13 ? 2.3 0.0 0.34 2.5e+02 14 31 .. 645 662 .. 640 665 .. 0.90 14 ? -2.0 0.0 7.3 5.5e+03 14 31 .. 685 702 .. 684 704 .. 0.86 15 ? 3.8 0.0 0.12 89 14 31 .. 725 742 .. 720 745 .. 0.91 16 ? 1.0 0.0 0.9 6.7e+02 14 31 .. 765 782 .. 764 785 .. 0.88 17 ? 1.2 0.0 0.76 5.7e+02 14 31 .. 805 822 .. 802 825 .. 0.89 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.87 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002327-T1 85 YQLLGDVRKAIEYHEKHL 102 8899***********987 PP == domain 2 score: 1.4 bits; conditional E-value: 0.67 DUF2977 13 sYvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002327-T1 124 AYQLLGDVRKAIEYHEKHL 142 6999************987 PP == domain 3 score: 1.1 bits; conditional E-value: 0.8 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++gi+++e l FUN_002327-T1 165 YRSLGEFRKGIEYHERHL 182 7889**********9876 PP == domain 4 score: 3.3 bits; conditional E-value: 0.16 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002327-T1 203 ITYQSLGDFRKAIEYHEKHL 222 8899*************987 PP == domain 5 score: 1.2 bits; conditional E-value: 0.77 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002327-T1 285 YQSLGDFRKAIEYHEKHL 302 7889***********987 PP == domain 6 score: 2.7 bits; conditional E-value: 0.25 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G l+++i+++e+ l FUN_002327-T1 323 IAYRSLGDLRKAIEYHEKHL 342 78999************987 PP == domain 7 score: 1.0 bits; conditional E-value: 0.89 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002327-T1 365 YQSLGDFRKAIEYHEKHL 382 7789***********987 PP == domain 8 score: -0.1 bits; conditional E-value: 1.9 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002327-T1 405 YQSLGDVRKAIEYHEKHL 422 7789***********987 PP == domain 9 score: 2.3 bits; conditional E-value: 0.34 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002327-T1 445 YYLLGDFRKAIEYHEKHL 462 8899***********987 PP == domain 10 score: 1.1 bits; conditional E-value: 0.81 DUF2977 14 YvlvGgledgidvdednl 31 Y G l+++i+++e+ l FUN_002327-T1 485 YRSLGDLRKAIEYHEKHL 502 7789***********987 PP == domain 11 score: 0.8 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++gi+++e l FUN_002327-T1 525 YRSLGEFRKGIEYHERHL 542 7789**********9876 PP == domain 12 score: 1.8 bits; conditional E-value: 0.48 DUF2977 12 isYvlvGgledgidvded 29 i Y G ++++i+++e+ FUN_002327-T1 563 IAYQSLGDFRKAIEYHEK 580 8999************96 PP == domain 13 score: 2.3 bits; conditional E-value: 0.34 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002327-T1 645 YYLLGDFRKAIEYHEKHL 662 8899***********987 PP == domain 14 score: -2.0 bits; conditional E-value: 7.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++i+++e+ l FUN_002327-T1 685 YRSLGDSRKAIEYHEKHL 702 6778999*******9876 PP == domain 15 score: 3.8 bits; conditional E-value: 0.12 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e++l FUN_002327-T1 725 YQLLGDFRKAIEYHEKQL 742 899************998 PP == domain 16 score: 1.0 bits; conditional E-value: 0.9 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002327-T1 765 YQSLGDFRKAIEYHEKDL 782 7789**********9877 PP == domain 17 score: 1.2 bits; conditional E-value: 0.76 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002327-T1 805 YQSLGDFRKAIEYHEKHL 822 7889***********987 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.24 1.8e+02 6 22 .. 81 97 .. 80 99 .. 0.92 2 ? 4.7 0.0 0.11 79 3 22 .. 118 137 .. 116 139 .. 0.89 3 ? -1.3 0.0 8.8 6.6e+03 5 21 .. 160 176 .. 158 177 .. 0.85 4 ? 2.0 0.0 0.81 6.1e+02 6 22 .. 201 217 .. 200 219 .. 0.92 5 ? 0.3 0.0 2.6 2e+03 5 22 .. 240 257 .. 235 260 .. 0.63 6 ? 3.9 0.1 0.19 1.4e+02 5 22 .. 280 297 .. 277 299 .. 0.93 7 ? 0.9 0.0 1.7 1.3e+03 7 22 .. 322 337 .. 320 339 .. 0.91 8 ? -0.7 0.0 5.7 4.3e+03 7 22 .. 362 377 .. 362 378 .. 0.86 9 ? 3.3 0.0 0.29 2.2e+02 6 22 .. 401 417 .. 400 419 .. 0.92 10 ? 5.1 0.0 0.081 61 6 22 .. 441 457 .. 440 459 .. 0.92 11 ? 2.4 0.0 0.56 4.2e+02 6 22 .. 481 497 .. 480 499 .. 0.93 12 ? 3.6 0.0 0.23 1.8e+02 5 22 .. 560 577 .. 557 579 .. 0.92 13 ? 2.0 0.1 0.79 5.9e+02 5 22 .. 600 617 .. 597 618 .. 0.90 14 ? 5.1 0.0 0.081 61 6 22 .. 641 657 .. 640 659 .. 0.92 15 ? 0.8 0.0 1.9 1.4e+03 7 22 .. 682 697 .. 681 698 .. 0.90 16 ? 3.7 0.0 0.23 1.7e+02 6 22 .. 721 737 .. 720 739 .. 0.92 17 ? 3.7 0.0 0.23 1.7e+02 6 22 .. 761 777 .. 760 779 .. 0.94 18 ? 3.6 0.1 0.24 1.8e+02 5 22 .. 800 817 .. 797 820 .. 0.92 19 ? -1.5 0.0 10 7.5e+03 4 26 .. 846 868 .. 845 870 .. 0.77 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.24 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd +A+++ FUN_002327-T1 81 LGNAYQLLGDVRKAIEY 97 89************986 PP == domain 2 score: 4.7 bits; conditional E-value: 0.11 TPR_6 3 llklalsylelgdkdeAkaa 22 + +l+ +y+ lgd +A+++ FUN_002327-T1 118 YRNLGNAYQLLGDVRKAIEY 137 5589*************986 PP == domain 3 score: -1.3 bits; conditional E-value: 8.8 TPR_6 5 klalsylelgdkdeAka 21 +l+ +y+ lg++ + ++ FUN_002327-T1 160 NLGNAYRSLGEFRKGIE 176 599*******9998876 PP == domain 4 score: 2.0 bits; conditional E-value: 0.81 TPR_6 6 lalsylelgdkdeAkaa 22 l+ y+ lgd+ +A+++ FUN_002327-T1 201 LGITYQSLGDFRKAIEY 217 899***********986 PP == domain 5 score: 0.3 bits; conditional E-value: 2.6 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ l d+ +A+++ FUN_002327-T1 240 NLGNAYESLSDFRKAIEY 257 366666666666666654 PP == domain 6 score: 3.9 bits; conditional E-value: 0.19 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002327-T1 280 YLGNAYQSLGDFRKAIEY 297 69*************986 PP == domain 7 score: 0.9 bits; conditional E-value: 1.7 TPR_6 7 alsylelgdkdeAkaa 22 + +y+ lgd +A+++ FUN_002327-T1 322 GIAYRSLGDLRKAIEY 337 789**********986 PP == domain 8 score: -0.7 bits; conditional E-value: 5.7 TPR_6 7 alsylelgdkdeAkaa 22 + y+ lgd+ +A+++ FUN_002327-T1 362 GNTYQSLGDFRKAIEY 377 568999*******986 PP == domain 9 score: 3.3 bits; conditional E-value: 0.29 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd +A+++ FUN_002327-T1 401 LGNAYQSLGDVRKAIEY 417 89************986 PP == domain 10 score: 5.1 bits; conditional E-value: 0.081 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002327-T1 441 LGNAYYLLGDFRKAIEY 457 8*************986 PP == domain 11 score: 2.4 bits; conditional E-value: 0.56 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd +A+++ FUN_002327-T1 481 LGSAYRSLGDLRKAIEY 497 799***********986 PP == domain 12 score: 3.6 bits; conditional E-value: 0.23 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002327-T1 560 NLGIAYQSLGDFRKAIEY 577 59*************986 PP == domain 13 score: 2.0 bits; conditional E-value: 0.79 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A ++ FUN_002327-T1 600 NLGNAYQSLGDFRKANEY 617 599************875 PP == domain 14 score: 5.1 bits; conditional E-value: 0.081 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002327-T1 641 LGNAYYLLGDFRKAIEY 657 8*************986 PP == domain 15 score: 0.8 bits; conditional E-value: 1.9 TPR_6 7 alsylelgdkdeAkaa 22 + +y+ lgd +A+++ FUN_002327-T1 682 GSAYRSLGDSRKAIEY 697 789999*******986 PP == domain 16 score: 3.7 bits; conditional E-value: 0.23 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002327-T1 721 LGNAYQLLGDFRKAIEY 737 89************986 PP == domain 17 score: 3.7 bits; conditional E-value: 0.23 TPR_6 6 lalsylelgdkdeAkaa 22 l+++y+ lgd+ +A+++ FUN_002327-T1 761 LGRAYQSLGDFRKAIEY 777 89************986 PP == domain 18 score: 3.6 bits; conditional E-value: 0.24 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002327-T1 800 NLGNAYQSLGDFRKAIEY 817 599************986 PP == domain 19 score: -1.5 bits; conditional E-value: 10 TPR_6 4 lklalsylelgdkdeAkaalqrl 26 + l++ ++lg++ A+++++ l FUN_002327-T1 846 FSLGQFEIALGMFVSAVKVFNTL 868 55777788889999999999877 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.2 0.0033 2.5 53 179 .. 13 139 .. 4 148 .. 0.51 2 ! 7.0 0.0 0.0068 5.1 45 141 .. 205 301 .. 198 307 .. 0.89 3 ! 12.1 0.0 0.00019 0.14 42 180 .. 322 460 .. 314 467 .. 0.90 4 ? 3.4 0.0 0.082 62 40 144 .. 440 544 .. 431 587 .. 0.75 5 ? 4.7 0.1 0.032 24 45 141 .. 565 661 .. 552 702 .. 0.71 6 ! 15.2 0.0 2e-05 0.015 37 142 .. 717 822 .. 705 832 .. 0.92 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0033 SNAP 53 eAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadlyeq 147 +A+e ++k ++ +++++ +ay++ ++++ d +A++ ek ei +e g ++ + ++++ y+ +d++kAie+ e+ ++ + FUN_002327-T1 13 KASEYHEKHLKITMEVGDRAREEKAYQNLPYAFQSLdDFRKAIKYHEKHLEIAIEVGDRVGEGNAYGNLGNAYQLL-GDVRKAIEYHEKHLEIAIE 107 5555555555555555555555555555554444432445555555555555555555555555555555555544.5555555555555555444 PP SNAP 148 eeaealankcllkvAdlsaelekyekAieiye 179 + +++ ++ + + l++ kAie e FUN_002327-T1 108 VGHRVGEGNAYRNLGNAYQLLGDVRKAIEYHE 139 44444444444444444444444444444444 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0068 SNAP 45 yklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYe 139 y+ ++++A e ++k e+++++++++ ++ay + ++y++ d +A+e ek ei +e g+ ++ + +++ y++ +d++kAie+ e FUN_002327-T1 205 YQSLGDFRKAIEYHEKHLEIEREIGDRTGEGTAYGNLGNAYESLsDFRKAIEYHEKHLEIAIEVGNRVGEGSAYGYLGNAYQSL-GDFRKAIEYHE 299 55556789999999***************************9875889*****************9999999999******987.********998 PP SNAP 140 qA 141 + FUN_002327-T1 300 KH 301 75 PP == domain 3 score: 12.1 bits; conditional E-value: 0.00019 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 + ay+ ++++A e ++k ++ +++++d +n y + y++ d +A+e ek ei +e g+ ++ + ++++ y++ +d++kAie FUN_002327-T1 322 GIAYRSLGDLRKAIEYHEKHLKIAIEVGDRDGEGNGYGSFGNTYQSLgDFRKAIEYHEKHLEIAIEVGNWVGKGNAYGNLGNAYQSL-GDVRKAIE 416 56899999999*********************************997799**********************************987.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ ++ + + +++ ++ + + l+++ kAie ek FUN_002327-T1 417 YHEKHLKIAIEVGHRVGEGNAYGNLGNAYYLLGDFRKAIEYHEK 460 ***99988888888888888888888888888888888887775 PP == domain 4 score: 3.4 bits; conditional E-value: 0.082 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + +nay l ++++A e ++k e+ +++++ ++ay +y++ d +A+e ek ei +e g+ + + ++++ y++ ++++k FUN_002327-T1 440 NLGNAYYLLGDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGSLGSAYRSLgDLRKAIEYHEKHLEIAIEVGNRVGEGGTYGNLGNAYRSL-GEFRKG 534 55788999999999999999999999999999999999999999999876888999999999999999998888888888999999876.888888 PP SNAP 135 ieaYeqAadl 144 ie+ e+ ++ FUN_002327-T1 535 IEYHERHLKI 544 8888876555 PP == domain 5 score: 4.7 bits; conditional E-value: 0.032 SNAP 45 yklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYe 139 y+ ++++A e ++k e+++++++++ ++ay + ++y++ d +A e ek +i +e g ++ + ++++ y +d++kAie+ e FUN_002327-T1 565 YQSLGDFRKAIEYHEKHSEIEREVGDRTGEGTAYGNLGNAYQSLgDFRKANEYHEKHLKIAIEVGDRVGEGNAYGNLGNAYYLL-GDFRKAIEYHE 659 555566777777777777777777777777777777777777765777777777777777777777777777777777777755.77777777776 PP SNAP 140 qA 141 + FUN_002327-T1 660 KH 661 64 PP == domain 6 score: 15.2 bits; conditional E-value: 2e-05 SNAP 37 lykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdl 131 y + +nay+l ++++A e ++k e+ +++++d +nay ++y++ d +A+e ek ei +e g+ ++ + ++++ y++ +d+ FUN_002327-T1 717 AYGNLGNAYQLLGDFRKAIEYHEKQLEIAIEVGDRDGEGNAYGSLGRAYQSLgDFRKAIEYHEKDLEIAIEVGNRFGEGNAYGNLGNAYQSL-GDF 811 677779*******************************************998799******************999999***********87.*** PP SNAP 132 ekAieaYeqAa 142 +kAie+ e+ FUN_002327-T1 812 RKAIEYHEKHL 822 *****999865 PP >> DUF7542 Family of unknown function (DUF7542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.93 7e+02 18 35 .. 44 61 .. 34 68 .. 0.84 2 ? 1.4 0.0 0.5 3.7e+02 17 35 .. 83 101 .. 78 112 .. 0.84 3 ? 1.1 0.0 0.61 4.6e+02 17 35 .. 123 141 .. 119 148 .. 0.86 4 ? -1.1 0.0 3 2.3e+03 17 35 .. 163 181 .. 159 187 .. 0.87 5 ? 2.2 0.0 0.27 2e+02 18 35 .. 204 221 .. 199 229 .. 0.87 6 ? 2.5 0.0 0.21 1.6e+02 17 35 .. 243 261 .. 237 268 .. 0.86 7 ? 2.2 0.0 0.27 2e+02 17 35 .. 283 301 .. 278 308 .. 0.87 8 ? 1.6 0.0 0.43 3.2e+02 15 35 .. 321 341 .. 316 347 .. 0.86 9 ? 4.5 0.0 0.054 41 14 35 .. 360 381 .. 358 389 .. 0.88 10 ? 3.5 0.0 0.11 82 17 35 .. 403 421 .. 398 432 .. 0.85 11 ? -1.3 0.0 3.5 2.6e+03 18 35 .. 444 461 .. 439 467 .. 0.83 12 ? 2.1 0.0 0.3 2.2e+02 17 35 .. 483 501 .. 476 508 .. 0.86 13 ? -1.1 0.0 2.9 2.2e+03 17 35 .. 523 541 .. 519 547 .. 0.87 14 ? 1.7 0.0 0.38 2.9e+02 18 35 .. 564 581 .. 559 588 .. 0.87 15 ? -1.8 0.0 4.8 3.6e+03 17 35 .. 603 621 .. 598 626 .. 0.85 16 ? -1.3 0.0 3.5 2.6e+03 18 35 .. 644 661 .. 639 667 .. 0.83 17 ? 4.9 0.0 0.04 30 14 35 .. 680 701 .. 673 707 .. 0.88 18 ? 0.4 0.0 1 7.7e+02 17 35 .. 723 741 .. 718 747 .. 0.85 19 ? 3.1 0.0 0.15 1.1e+02 17 36 .. 763 782 .. 758 788 .. 0.87 20 ? 2.4 0.0 0.23 1.7e+02 17 35 .. 803 821 .. 798 835 .. 0.88 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.93 DUF7542 18 tfdslraARealddHese 35 +f+sl + R+a++ He++ FUN_002327-T1 44 AFQSLDDFRKAIKYHEKH 61 799999999999999976 PP == domain 2 score: 1.4 bits; conditional E-value: 0.5 DUF7542 17 etfdslraARealddHese 35 ++++ l++ R+a++ He++ FUN_002327-T1 83 NAYQLLGDVRKAIEYHEKH 101 68999************86 PP == domain 3 score: 1.1 bits; conditional E-value: 0.61 DUF7542 17 etfdslraARealddHese 35 ++++ l++ R+a++ He++ FUN_002327-T1 123 NAYQLLGDVRKAIEYHEKH 141 68999************86 PP == domain 4 score: -1.1 bits; conditional E-value: 3 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+ ++ He++ FUN_002327-T1 163 NAYRSLGEFRKGIEYHERH 181 6899*************86 PP == domain 5 score: 2.2 bits; conditional E-value: 0.27 DUF7542 18 tfdslraARealddHese 35 t++sl++ R+a++ He++ FUN_002327-T1 204 TYQSLGDFRKAIEYHEKH 221 89**************86 PP == domain 6 score: 2.5 bits; conditional E-value: 0.21 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002327-T1 243 NAYESLSDFRKAIEYHEKH 261 789**************86 PP == domain 7 score: 2.2 bits; conditional E-value: 0.27 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002327-T1 283 NAYQSLGDFRKAIEYHEKH 301 689**************86 PP == domain 8 score: 1.6 bits; conditional E-value: 0.43 DUF7542 15 feetfdslraARealddHese 35 f ++ sl++ R+a++ He++ FUN_002327-T1 321 FGIAYRSLGDLRKAIEYHEKH 341 566899*************76 PP == domain 9 score: 4.5 bits; conditional E-value: 0.054 DUF7542 14 efeetfdslraARealddHese 35 +f +t++sl++ R+a++ He++ FUN_002327-T1 360 SFGNTYQSLGDFRKAIEYHEKH 381 5789****************86 PP == domain 10 score: 3.5 bits; conditional E-value: 0.11 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002327-T1 403 NAYQSLGDVRKAIEYHEKH 421 689**************85 PP == domain 11 score: -1.3 bits; conditional E-value: 3.5 DUF7542 18 tfdslraARealddHese 35 ++ l++ R+a++ He++ FUN_002327-T1 444 AYYLLGDFRKAIEYHEKH 461 67789999*******986 PP == domain 12 score: 2.1 bits; conditional E-value: 0.3 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002327-T1 483 SAYRSLGDLRKAIEYHEKH 501 789**************86 PP == domain 13 score: -1.1 bits; conditional E-value: 2.9 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+ ++ He++ FUN_002327-T1 523 NAYRSLGEFRKGIEYHERH 541 6899*************86 PP == domain 14 score: 1.7 bits; conditional E-value: 0.38 DUF7542 18 tfdslraARealddHese 35 +++sl++ R+a++ He++ FUN_002327-T1 564 AYQSLGDFRKAIEYHEKH 581 799*************76 PP == domain 15 score: -1.8 bits; conditional E-value: 4.8 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a + He++ FUN_002327-T1 603 NAYQSLGDFRKANEYHEKH 621 68999*******9999975 PP == domain 16 score: -1.3 bits; conditional E-value: 3.5 DUF7542 18 tfdslraARealddHese 35 ++ l++ R+a++ He++ FUN_002327-T1 644 AYYLLGDFRKAIEYHEKH 661 67789999*******986 PP == domain 17 score: 4.9 bits; conditional E-value: 0.04 DUF7542 14 efeetfdslraARealddHese 35 +f +++ sl++ R+a++ He++ FUN_002327-T1 680 SFGSAYRSLGDSRKAIEYHEKH 701 68899***************86 PP == domain 18 score: 0.4 bits; conditional E-value: 1 DUF7542 17 etfdslraARealddHese 35 ++++ l++ R+a++ He++ FUN_002327-T1 723 NAYQLLGDFRKAIEYHEKQ 741 68999************87 PP == domain 19 score: 3.1 bits; conditional E-value: 0.15 DUF7542 17 etfdslraARealddHeset 36 +++sl++ R+a++ He++ FUN_002327-T1 763 RAYQSLGDFRKAIEYHEKDL 782 689**************986 PP == domain 20 score: 2.4 bits; conditional E-value: 0.23 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002327-T1 803 NAYQSLGDFRKAIEYHEKH 821 689**************86 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.11 81 219 243 .. 79 103 .. 73 107 .. 0.89 2 ? 2.5 0.0 0.15 1.2e+02 220 243 .. 120 143 .. 116 147 .. 0.88 3 ? -1.9 0.0 3.2 2.4e+03 221 246 .. 201 226 .. 198 227 .. 0.83 4 ? -0.5 0.0 1.2 9.2e+02 219 243 .. 239 263 .. 234 266 .. 0.84 5 ? 1.2 0.0 0.38 2.8e+02 219 243 .. 279 303 .. 274 307 .. 0.86 6 ? 1.6 0.0 0.28 2.1e+02 219 244 .. 319 344 .. 315 347 .. 0.89 7 ? -0.7 0.0 1.5 1.1e+03 219 243 .. 359 383 .. 358 392 .. 0.86 8 ? 2.8 0.0 0.12 94 219 244 .. 399 424 .. 391 427 .. 0.89 9 ? 2.6 0.0 0.14 1e+02 219 243 .. 439 463 .. 435 467 .. 0.88 10 ? 4.0 0.0 0.055 41 218 243 .. 478 503 .. 474 507 .. 0.89 11 ? 1.1 0.0 0.42 3.1e+02 219 245 .. 559 585 .. 554 588 .. 0.86 12 ? -0.8 0.0 1.6 1.2e+03 219 244 .. 599 624 .. 595 627 .. 0.86 13 ? 2.7 0.0 0.13 1e+02 219 243 .. 639 663 .. 634 667 .. 0.88 14 ! 6.8 0.0 0.0076 5.7 218 243 .. 678 703 .. 674 707 .. 0.89 15 ? 2.7 0.0 0.13 99 219 243 .. 719 743 .. 712 747 .. 0.89 16 ? -0.3 0.0 1.1 8e+02 219 242 .. 759 782 .. 754 786 .. 0.83 17 ? 2.4 0.0 0.16 1.2e+02 219 246 .. 799 826 .. 794 828 .. 0.88 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.11 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA +y +k+++ FUN_002327-T1 79 GNLGNAYQLLGDVRKAIEYHEKHLE 103 56899****************9976 PP == domain 2 score: 2.5 bits; conditional E-value: 0.15 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ llg+ rkA +y +k+++ FUN_002327-T1 120 NLGNAYQLLGDVRKAIEYHEKHLE 143 5899****************9976 PP == domain 3 score: -1.9 bits; conditional E-value: 3.2 TPR_15 221 yAaAllllgqnrkALpyfrkkaaqnk 246 ++ + lg+ rkA +y +k+++ ++ FUN_002327-T1 201 LGITYQSLGDFRKAIEYHEKHLEIER 226 5667899*************988765 PP == domain 4 score: -0.5 bits; conditional E-value: 1.2 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ l++ rkA +y +k+++ FUN_002327-T1 239 GNLGNAYESLSDFRKAIEYHEKHLE 263 5688999999999999999999875 PP == domain 5 score: 1.2 bits; conditional E-value: 0.38 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002327-T1 279 GYLGNAYQSLGDFRKAIEYHEKHLE 303 56899***************99876 PP == domain 6 score: 1.6 bits; conditional E-value: 0.28 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002327-T1 319 GNFGIAYRSLGDLRKAIEYHEKHLKI 344 57999*****************9875 PP == domain 7 score: -0.7 bits; conditional E-value: 1.5 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ + lg+ rkA +y +k+++ FUN_002327-T1 359 GSFGNTYQSLGDFRKAIEYHEKHLE 383 57899999*************9976 PP == domain 8 score: 2.8 bits; conditional E-value: 0.12 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002327-T1 399 GNLGNAYQSLGDVRKAIEYHEKHLKI 424 67899*****************9875 PP == domain 9 score: 2.6 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA +y +k+++ FUN_002327-T1 439 GNLGNAYYLLGDFRKAIEYHEKHLE 463 56899****************9976 PP == domain 10 score: 4.0 bits; conditional E-value: 0.055 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ +++A+ lg+ rkA +y +k+++ FUN_002327-T1 478 YGSLGSAYRSLGDLRKAIEYHEKHLE 503 5789******************9976 PP == domain 11 score: 1.1 bits; conditional E-value: 0.42 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqn 245 + ++ A+ lg+ rkA +y +k+ + + FUN_002327-T1 559 GNLGIAYQSLGDFRKAIEYHEKHSEIE 585 56889*****************98766 PP == domain 12 score: -0.8 bits; conditional E-value: 1.6 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002327-T1 599 GNLGNAYQSLGDFRKANEYHEKHLKI 624 56899**************9999875 PP == domain 13 score: 2.7 bits; conditional E-value: 0.13 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA +y +k+++ FUN_002327-T1 639 GNLGNAYYLLGDFRKAIEYHEKHLE 663 56899****************9976 PP == domain 14 score: 6.8 bits; conditional E-value: 0.0076 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ +++A+ lg++rkA +y +k+++ FUN_002327-T1 678 YGSFGSAYRSLGDSRKAIEYHEKHLE 703 5789******************9976 PP == domain 15 score: 2.7 bits; conditional E-value: 0.13 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA +y +k+++ FUN_002327-T1 719 GNLGNAYQLLGDFRKAIEYHEKQLE 743 66899*****************976 PP == domain 16 score: -0.3 bits; conditional E-value: 1.1 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ lg+ rkA +y +k + FUN_002327-T1 759 GSLGRAYQSLGDFRKAIEYHEKDL 782 568889999********9999865 PP == domain 17 score: 2.4 bits; conditional E-value: 0.16 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002327-T1 799 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 826 56899*****************998765 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 1.8 1.4e+03 24 62 .. 44 85 .. 18 101 .. 0.65 2 ? -0.2 0.0 2.1 1.6e+03 29 63 .. 89 126 .. 80 130 .. 0.82 3 ? 3.5 0.0 0.15 1.1e+02 29 67 .. 129 170 .. 120 181 .. 0.85 4 ? 4.8 0.0 0.057 43 25 70 .. 205 253 .. 178 264 .. 0.81 5 ? 1.5 0.0 0.62 4.7e+02 24 61 .. 284 331 .. 279 358 .. 0.71 6 ? 3.0 0.0 0.21 1.6e+02 24 70 .. 364 413 .. 360 438 .. 0.80 7 ? -1.7 0.0 6 4.5e+03 30 65 .. 450 488 .. 443 493 .. 0.72 8 ? 3.3 0.0 0.17 1.3e+02 26 66 .. 486 529 .. 479 548 .. 0.76 9 ? 6.2 0.0 0.022 16 26 70 .. 566 613 .. 557 624 .. 0.78 10 ? -0.9 0.0 3.5 2.6e+03 30 70 .. 650 693 .. 642 707 .. 0.71 11 ? 1.6 0.0 0.57 4.3e+02 25 69 .. 765 812 .. 759 823 .. 0.74 12 ? -0.3 0.0 2.3 1.7e+03 24 52 .. 804 832 .. 794 835 .. 0.83 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 1.8 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvL 62 +f+s + ++A+ +e+ e +v +++ + +Lgn + FUN_002327-T1 44 AFQSLDDFRKAIKYHEKHLEIAIEVGDRVGEgnaYGNLGNAY 85 689999999999999998888888888885511134455554 PP == domain 2 score: -0.2 bits; conditional E-value: 2.1 WH_Halo_primase 29 relydAleaYepereweqkvknei...ssprsLgnvLk 63 ++++A+e +e+ e +v ++ r+Lgn ++ FUN_002327-T1 89 GDVRKAIEYHEKHLEIAIEVGHRVgegNAYRNLGNAYQ 126 5899********99999999999955445899999885 PP == domain 3 score: 3.5 bits; conditional E-value: 0.15 WH_Halo_primase 29 relydAleaYepereweqkvknei...ssprsLgnvLkkard 67 ++++A+e +e+ e +v +++ + r+Lgn +++ + FUN_002327-T1 129 GDVRKAIEYHEKHLEIAIEVGDRVgegGTYRNLGNAYRSLGE 170 5899********************776779******998665 PP == domain 4 score: 4.8 bits; conditional E-value: 0.057 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 +s + ++A+e +e+ e e+++ ++ +Lgn +++ +d r+ FUN_002327-T1 205 YQSLGDFRKAIEYHEKHLEIEREIGDRTgegTAYGNLGNAYESLSDFRK 253 5788899********************9443336789999998888776 PP == domain 5 score: 1.5 bits; conditional E-value: 0.62 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss..........prsLgnv 61 + +s + ++A+e +e+ e +v n++ + rsLg + FUN_002327-T1 284 AYQSLGDFRKAIEYHEKHLEIAIEVGNRVGQgnaygnfgiaYRSLGDL 331 567788899999999998888888888887755555555555555544 PP == domain 6 score: 3.0 bits; conditional E-value: 0.21 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 + +s + ++A+e +e+ e +v n++ +Lgn +++ d r+ FUN_002327-T1 364 TYQSLGDFRKAIEYHEKHLEIAIEVGNWVGKgnaYGNLGNAYQSLGDVRK 413 5678889999*****99999999999999552225677777777776665 PP == domain 7 score: -1.7 bits; conditional E-value: 6 WH_Halo_primase 30 elydAleaYepereweqkvknei...ssprsLgnvLkka 65 + ++A+e +e+ e +v +++ s sLg +++ FUN_002327-T1 450 DFRKAIEYHEKHLEIAIEVGDRVgegSAYGSLGSAYRSL 488 789999999999998888888885544455666666654 PP == domain 8 score: 3.3 bits; conditional E-value: 0.17 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkar 66 s +l++A+e +e+ e +v n++ + +Lgn +++ FUN_002327-T1 486 RSLGDLRKAIEYHEKHLEIAIEVGNRVgegGTYGNLGNAYRSLG 529 57789**************9******944444566666666544 PP == domain 9 score: 6.2 bits; conditional E-value: 0.022 WH_Halo_primase 26 hsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 +s + ++A+e +e+ e e++v ++ + +Lgn +++ d r+ FUN_002327-T1 566 QSLGDFRKAIEYHEKHSEIEREVGDRTGEgtaYGNLGNAYQSLGDFRK 613 678899********************9652235567777776666554 PP == domain 10 score: -0.9 bits; conditional E-value: 3.5 WH_Halo_primase 30 elydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + ++A+e +e+ e +v +++ s s g +++ d+r+ FUN_002327-T1 650 DFRKAIEYHEKHLEIAIEVGDRVgegSAYGSFGSAYRSLGDSRK 693 78899999999999999999999554344556666666666555 PP == domain 11 score: 1.6 bits; conditional E-value: 0.57 WH_Halo_primase 25 fhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhr 69 +s + ++A+e +e++ e +v n+ + +Lgn +++ d r FUN_002327-T1 765 YQSLGDFRKAIEYHEKDLEIAIEVGNRFGEgnaYGNLGNAYQSLGDFR 812 567889999999999999999999999955222556777777666655 PP == domain 12 score: -0.3 bits; conditional E-value: 2.3 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei 52 + +s + ++A+e +e+ e ++v +++ FUN_002327-T1 804 AYQSLGDFRKAIEYHEKHLEIAKEVGDRV 832 67888999*******99988888887776 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.39 3e+02 3 20 .. 77 94 .. 75 96 .. 0.88 2 ? 3.6 0.0 0.26 1.9e+02 3 20 .. 117 134 .. 115 136 .. 0.89 3 ? -1.0 0.0 8.2 6.1e+03 5 20 .. 199 214 .. 196 215 .. 0.87 4 ? -0.4 0.0 4.9 3.7e+03 3 20 .. 277 294 .. 275 295 .. 0.85 5 ? -0.1 0.0 4 3e+03 3 20 .. 397 414 .. 396 415 .. 0.87 6 ? 4.5 0.0 0.13 99 3 20 .. 437 454 .. 435 456 .. 0.89 7 ? 2.6 0.0 0.53 4e+02 3 20 .. 557 574 .. 555 576 .. 0.89 8 ? 1.6 0.0 1.2 8.7e+02 3 20 .. 597 614 .. 595 615 .. 0.89 9 ? 4.5 0.0 0.13 99 3 20 .. 637 654 .. 635 656 .. 0.89 10 ? 4.5 0.0 0.14 1e+02 3 20 .. 717 734 .. 715 736 .. 0.89 11 ? 2.0 0.0 0.82 6.2e+02 4 20 .. 758 774 .. 756 776 .. 0.87 12 ? 1.7 0.0 1.1 8.1e+02 3 20 .. 797 814 .. 795 816 .. 0.89 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.39 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+++lGd A FUN_002327-T1 77 AYGNLGNAYQLLGDVRKA 94 6789**********8876 PP == domain 2 score: 3.6 bits; conditional E-value: 0.26 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+++lGd A FUN_002327-T1 117 AYRNLGNAYQLLGDVRKA 134 789***********8876 PP == domain 3 score: -1.0 bits; conditional E-value: 8.2 TPR_4 5 laLArallalGdldeA 20 +L+ +++ lGd+ A FUN_002327-T1 199 GNLGITYQSLGDFRKA 214 699*********9877 PP == domain 4 score: -0.4 bits; conditional E-value: 4.9 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a++ lGd+ A FUN_002327-T1 277 AYGYLGNAYQSLGDFRKA 294 66789*********9877 PP == domain 5 score: -0.1 bits; conditional E-value: 4 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd A FUN_002327-T1 397 AYGNLGNAYQSLGDVRKA 414 6789**********8766 PP == domain 6 score: 4.5 bits; conditional E-value: 0.13 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+++lGd+ A FUN_002327-T1 437 AYGNLGNAYYLLGDFRKA 454 6789**********9887 PP == domain 7 score: 2.6 bits; conditional E-value: 0.53 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002327-T1 557 AYGNLGIAYQSLGDFRKA 574 789***********9887 PP == domain 8 score: 1.6 bits; conditional E-value: 1.2 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002327-T1 597 AYGNLGNAYQSLGDFRKA 614 7789**********9877 PP == domain 9 score: 4.5 bits; conditional E-value: 0.13 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+++lGd+ A FUN_002327-T1 637 AYGNLGNAYYLLGDFRKA 654 6789**********9887 PP == domain 10 score: 4.5 bits; conditional E-value: 0.14 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+++lGd+ A FUN_002327-T1 717 AYGNLGNAYQLLGDFRKA 734 6789**********9887 PP == domain 11 score: 2.0 bits; conditional E-value: 0.82 TPR_4 4 llaLArallalGdldeA 20 + L+ra++ lGd+ A FUN_002327-T1 758 YGSLGRAYQSLGDFRKA 774 6679*********9887 PP == domain 12 score: 1.7 bits; conditional E-value: 1.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002327-T1 797 AYGNLGNAYQSLGDFRKA 814 6789**********9887 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.065 49 37 73 .. 76 112 .. 45 113 .. 0.89 2 ? 2.0 0.0 0.28 2.1e+02 38 67 .. 117 146 .. 115 152 .. 0.86 3 ? -0.6 0.0 1.7 1.3e+03 39 64 .. 198 223 .. 195 232 .. 0.86 4 ? 1.5 0.0 0.38 2.8e+02 38 70 .. 237 269 .. 231 273 .. 0.87 5 ? 1.4 0.0 0.41 3.1e+02 39 70 .. 278 309 .. 275 314 .. 0.84 6 ? -1.3 0.0 2.8 2.1e+03 38 64 .. 317 343 .. 314 350 .. 0.81 7 ? 0.7 0.0 0.67 5e+02 39 68 .. 358 387 .. 354 392 .. 0.83 8 ? 4.3 0.0 0.056 42 38 72 .. 397 431 .. 394 433 .. 0.90 9 ? 3.6 0.0 0.091 68 38 67 .. 437 466 .. 435 472 .. 0.86 10 ? 1.9 0.0 0.29 2.2e+02 38 70 .. 477 509 .. 475 513 .. 0.84 11 ? -0.9 0.0 2.2 1.6e+03 38 62 .. 557 581 .. 532 591 .. 0.88 12 ? 0.2 0.0 0.99 7.4e+02 38 64 .. 597 623 .. 583 633 .. 0.86 13 ? 3.6 0.0 0.088 66 38 67 .. 637 666 .. 634 672 .. 0.86 14 ? -1.9 0.0 4.2 3.2e+03 39 67 .. 678 706 .. 676 713 .. 0.81 15 ? 1.6 0.1 0.37 2.8e+02 37 65 .. 716 744 .. 691 751 .. 0.82 16 ? 0.3 0.0 0.89 6.7e+02 38 65 .. 757 784 .. 755 792 .. 0.82 17 ? 3.5 0.1 0.094 71 38 70 .. 797 829 .. 795 908 .. 0.80 18 ? -2.6 0.0 7.1 5.4e+03 38 74 .. 889 925 .. 879 930 .. 0.80 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.065 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 +a+ +l++ y gd+++A+++ e+ +e ++ gh + FUN_002327-T1 76 NAYGNLGNAYQLLGDVRKAIEYHEKHLEIAIEVGHRV 112 57899**********************9999999875 PP == domain 2 score: 2.0 bits; conditional E-value: 0.28 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ +l++ y gd+++A+++ e+ +e ++ FUN_002327-T1 117 AYRNLGNAYQLLGDVRKAIEYHEKHLEIAI 146 7899*******************9888665 PP == domain 3 score: -0.6 bits; conditional E-value: 1.7 RPN7 39 ledlaehyakigdlenAlkayerare 64 + +l+ y + gd+++A+++ e+ +e FUN_002327-T1 198 YGNLGITYQSLGDFRKAIEYHEKHLE 223 6788889*************999766 PP == domain 4 score: 1.5 bits; conditional E-value: 0.38 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ +l++ y++ d+++A+++ e+ +e ++ g FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEYHEKHLEIAIEVG 269 7889*******************9998777665 PP == domain 5 score: 1.4 bits; conditional E-value: 0.41 RPN7 39 ledlaehyakigdlenAlkayerarekttslg 70 + l++ y + gd+++A+++ e+ +e ++ g FUN_002327-T1 278 YGYLGNAYQSLGDFRKAIEYHEKHLEIAIEVG 309 5668999***************9998777666 PP == domain 6 score: -1.3 bits; conditional E-value: 2.8 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +++ y + gdl++A+++ e+ ++ FUN_002327-T1 317 AYGNFGIAYRSLGDLRKAIEYHEKHLK 343 56677778999*********9998765 PP == domain 7 score: 0.7 bits; conditional E-value: 0.67 RPN7 39 ledlaehyakigdlenAlkayerarektts 68 + +++ y + gd+++A+++ e+ +e ++ FUN_002327-T1 358 YGSFGNTYQSLGDFRKAIEYHEKHLEIAIE 387 5678999***************98886665 PP == domain 8 score: 4.3 bits; conditional E-value: 0.056 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + gd+++A+++ e+ ++ ++ gh FUN_002327-T1 397 AYGNLGNAYQSLGDVRKAIEYHEKHLKIAIEVGHR 431 7889********************99998888886 PP == domain 9 score: 3.6 bits; conditional E-value: 0.091 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ +l++ y+ gd+++A+++ e+ +e ++ FUN_002327-T1 437 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAI 466 7889*******************9888665 PP == domain 10 score: 1.9 bits; conditional E-value: 0.29 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l+ y + gdl++A+++ e+ +e ++ g FUN_002327-T1 477 AYGSLGSAYRSLGDLRKAIEYHEKHLEIAIEVG 509 56789999***************9998777666 PP == domain 11 score: -0.9 bits; conditional E-value: 2.2 RPN7 38 aledlaehyakigdlenAlkayera 62 a+ +l+ y + gd+++A+++ e+ FUN_002327-T1 557 AYGNLGIAYQSLGDFRKAIEYHEKH 581 677899999***********99875 PP == domain 12 score: 0.2 bits; conditional E-value: 0.99 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A ++ e+ ++ FUN_002327-T1 597 AYGNLGNAYQSLGDFRKANEYHEKHLK 623 7889****************9998776 PP == domain 13 score: 3.6 bits; conditional E-value: 0.088 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ +l++ y+ gd+++A+++ e+ +e ++ FUN_002327-T1 637 AYGNLGNAYYLLGDFRKAIEYHEKHLEIAI 666 7889*******************9888665 PP == domain 14 score: -1.9 bits; conditional E-value: 4.2 RPN7 39 ledlaehyakigdlenAlkayerarektt 67 + ++ y + gd ++A+++ e+ +e ++ FUN_002327-T1 678 YGSFGSAYRSLGDSRKAIEYHEKHLEIAI 706 5567888999***********99888665 PP == domain 15 score: 1.6 bits; conditional E-value: 0.37 RPN7 37 raledlaehyakigdlenAlkayerarek 65 +a+ +l++ y gd+++A+++ e+ +e FUN_002327-T1 716 NAYGNLGNAYQLLGDFRKAIEYHEKQLEI 744 68999*****************9998775 PP == domain 16 score: 0.3 bits; conditional E-value: 0.89 RPN7 38 aledlaehyakigdlenAlkayerarek 65 a+ l+ y + gd+++A+++ e+ +e FUN_002327-T1 757 AYGSLGRAYQSLGDFRKAIEYHEKDLEI 784 67789999*************9986665 PP == domain 17 score: 3.5 bits; conditional E-value: 0.094 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ +l++ y + gd+++A+++ e+ +e + g FUN_002327-T1 797 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVG 829 78899*****************99888666555 PP == domain 18 score: -2.6 bits; conditional E-value: 7.1 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkid 74 + ++ ++ig+ ++Al a + r +t s + i+ FUN_002327-T1 889 SYCAKWRLLLRIGKTDEALFAADQGRAQTLSDNLLIQ 925 5667788899*********999999999888776666 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 1.5 1.1e+03 20 58 .. 62 102 .. 47 107 .. 0.77 2 ? 2.8 0.3 0.31 2.3e+02 19 58 .. 101 142 .. 80 147 .. 0.74 3 ? -1.7 0.0 8.1 6.1e+03 3 19 .. 161 177 .. 159 184 .. 0.76 4 ? 2.7 0.0 0.34 2.5e+02 30 57 .. 234 261 .. 200 267 .. 0.59 5 ? 4.5 0.2 0.091 69 3 55 .. 241 299 .. 232 306 .. 0.59 6 ? 3.8 0.2 0.16 1.2e+02 3 53 .. 281 337 .. 273 346 .. 0.69 7 ? 3.0 0.0 0.26 2e+02 4 56 .. 362 420 .. 360 427 .. 0.69 8 ! 8.9 0.3 0.0039 2.9 3 59 .. 401 463 .. 392 467 .. 0.81 9 ! 7.9 0.3 0.008 6 3 58 .. 441 502 .. 440 506 .. 0.83 10 ? 0.8 0.0 1.3 9.9e+02 3 19 .. 561 577 .. 560 580 .. 0.89 11 ! 9.6 0.3 0.0023 1.8 3 59 .. 601 663 .. 600 667 .. 0.82 12 ? 2.1 0.2 0.51 3.8e+02 4 53 .. 682 737 .. 680 745 .. 0.74 13 ? 5.3 0.3 0.054 41 3 56 .. 761 820 .. 760 826 .. 0.71 14 ? -1.5 0.0 7 5.3e+03 7 27 .. 845 865 .. 841 872 .. 0.82 15 ? -0.3 0.4 2.9 2.2e+03 5 38 .. 895 929 .. 892 930 .. 0.83 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 1.5 TPR_16 20 leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 le a++ + A+ +lG a+ +g++ +A+++ ++ l FUN_002327-T1 62 LEIAIEVGdrVGEGNAYGNLGNAYQLLGDVRKAIEYHEKHL 102 55555555664567899999999999999999998866666 PP == domain 2 score: 2.8 bits; conditional E-value: 0.31 TPR_16 19 aleaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 le a++ + A+++lG a+ +g++ +A+++ ++ l FUN_002327-T1 101 HLEIAIEVGhrVGEGNAYRNLGNAYQLLGDVRKAIEYHEKHL 142 4777777777756789******************99877666 PP == domain 3 score: -1.7 bits; conditional E-value: 8.1 TPR_16 3 laraalaagdyddAaaa 19 l++a++ +g+++ +++ FUN_002327-T1 161 LGNAYRSLGEFRKGIEY 177 78888888888887765 PP == domain 4 score: 2.7 bits; conditional E-value: 0.34 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraa 57 +A+ +lG a++ + ++ +A+++ ++ FUN_002327-T1 234 EGTAYGNLGNAYESLSDFRKAIEYHEKH 261 5678888888888888888888775555 PP == domain 5 score: 4.5 bits; conditional E-value: 0.091 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayr 55 l++a+ + d++ A+++ le a++ + A+ +lG a+ +g++ +A+++ + FUN_002327-T1 241 LGNAYESLSDFRKAIEYhekhLEIAIEVGnrVGEGSAYGYLGNAYQSLGDFRKAIEYHE 299 34444444555555432222245555555775567788888888888888877777655 PP == domain 6 score: 3.8 bits; conditional E-value: 0.16 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ le a++ + A+ + G a+ +g+l +A+++ FUN_002327-T1 281 LGNAYQSLGDFRKAIEYhekhLEIAIEVGnrVGQGNAYGNFGIAYRSLGDLRKAIEY 337 588888888888888653333666666667755667777777777777777777766 PP == domain 7 score: 3.0 bits; conditional E-value: 0.26 TPR_16 4 araalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayra 56 ++ + +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ FUN_002327-T1 362 GNTYQSLGDFRKAIEYhekhLEIAIEVGnwVGKGNAYGNLGNAYQSLGDVRKAIEYHEK 420 66777778888887643333777777777755777888888888888888888877555 PP == domain 8 score: 8.9 bits; conditional E-value: 0.0039 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd + A+++ l+ a++ + A+ +lG a++ +g++ +A+++ ++ l+ FUN_002327-T1 401 LGNAYQSLGDVRKAIEYhekhLKIAIEVGhrVGEGNAYGNLGNAYYLLGDFRKAIEYHEKHLE 463 788888888888888753333667777779977899*******************98777665 PP == domain 9 score: 7.9 bits; conditional E-value: 0.008 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd++ A+++ le a++ + A+ lG a+ +g+l +A+++ ++ l FUN_002327-T1 441 LGNAYYLLGDFRKAIEYhekhLEIAIEVGdrVGEGSAYGSLGSAYRSLGDLRKAIEYHEKHL 502 789999999999998754444999999999977899*******************9876666 PP == domain 10 score: 0.8 bits; conditional E-value: 1.3 TPR_16 3 laraalaagdyddAaaa 19 l+ a+ +gd++ A+++ FUN_002327-T1 561 LGIAYQSLGDFRKAIEY 577 7999**********986 PP == domain 11 score: 9.6 bits; conditional E-value: 0.0023 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A ++ l+ a++ + A+ +lG a++ +g++ +A+++ ++ l+ FUN_002327-T1 601 LGNAYQSLGDFRKANEYhekhLKIAIEVGdrVGEGNAYGNLGNAYYLLGDFRKAIEYHEKHLE 663 799999999999997653333778888889977999*******************99777665 PP == domain 12 score: 2.1 bits; conditional E-value: 0.51 TPR_16 4 araalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 + a++ +gd + A+++ le a++ + A+ +lG a+ +g++ +A+++ FUN_002327-T1 682 GSAYRSLGDSRKAIEYhekhLEIAIEVGkrEGEGNAYGNLGNAYQLLGDFRKAIEY 737 56677777777776543333778888888877888999999999999999999865 PP == domain 13 score: 5.3 bits; conditional E-value: 0.054 TPR_16 3 laraalaagdyddAaaa....leaalrrn...PeaaaAllglGlallrqgrlaeAaaayra 56 l+ra+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ FUN_002327-T1 761 LGRAYQSLGDFRKAIEYhekdLEIAIEVGnrfG-EGNAYGNLGNAYQSLGDFRKAIEYHEK 820 688999999999998654444777777777765.567888888888888888888877555 PP == domain 14 score: -1.5 bits; conditional E-value: 7 TPR_16 7 alaagdyddAaaaleaalrrn 27 ++ +g+++ A+ + a++ + FUN_002327-T1 845 YFSLGQFEIALGMFVSAVKVF 865 788999999999999888865 PP == domain 15 score: -0.3 bits; conditional E-value: 2.9 TPR_16 5 raalaagdyddAaaaleaalrrn.PeaaaAllglG 38 r++l+ g+ d+A+ a+++ +++ ++ +++gl+ FUN_002327-T1 895 RLLLRIGKTDEALFAADQGRAQTlSDNLLIQYGLA 929 67899999999999999999888888888888887 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.75 5.7e+02 36 67 .. 77 109 .. 73 137 .. 0.57 2 ? 0.3 0.0 1.3 1e+03 34 67 .. 115 149 .. 112 155 .. 0.80 3 ? 1.0 0.0 0.83 6.2e+02 30 69 .. 198 237 .. 197 248 .. 0.87 4 ? 0.3 0.0 1.4 1e+03 30 62 .. 238 270 .. 231 281 .. 0.55 5 ? 0.6 0.0 1.1 8.1e+02 30 67 .. 278 315 .. 274 319 .. 0.81 6 ? -1.5 0.0 5.1 3.8e+03 30 57 .. 318 345 .. 316 355 .. 0.79 7 ? -1.4 0.0 4.6 3.5e+03 31 68 .. 359 396 .. 358 407 .. 0.80 8 ? 1.5 0.0 0.57 4.3e+02 30 67 .. 398 435 .. 394 458 .. 0.74 9 ? 0.2 0.0 1.5 1.1e+03 30 61 .. 478 509 .. 473 549 .. 0.82 10 ? -1.0 0.0 3.6 2.7e+03 30 68 .. 558 596 .. 556 609 .. 0.80 11 ? -2.0 0.0 6.9 5.2e+03 37 66 .. 638 668 .. 631 679 .. 0.57 12 ? -0.5 0.0 2.5 1.9e+03 36 66 .. 717 748 .. 711 757 .. 0.64 13 ? -0.5 0.0 2.4 1.8e+03 30 67 .. 758 795 .. 755 799 .. 0.78 14 ? 0.3 0.0 1.4 1e+03 30 67 .. 798 835 .. 794 838 .. 0.71 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.75 CODH_A_N 36 kvktLgdleevLnrarsllkeelk.LekaldaG 67 + +Lg++ ++L +r++++ ++k Le a++ G FUN_002327-T1 77 AYGNLGNAYQLLGDVRKAIEYHEKhLEIAIEVG 109 555666666666666666665555543333333 PP == domain 2 score: 0.3 bits; conditional E-value: 1.3 CODH_A_N 34 GekvktLgdleevLnrarsllkeelk.LekaldaG 67 G++ ++Lg++ ++L +r++++ ++k Le a++ G FUN_002327-T1 115 GNAYRNLGNAYQLLGDVRKAIEYHEKhLEIAIEVG 149 77788999999999999999988776677776665 PP == domain 3 score: 1.0 bits; conditional E-value: 0.83 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G + Lgd +++++ ++ l+ e ++++ G+a FUN_002327-T1 198 YGNLGITYQSLGDFRKAIEYHEKHLEIEREIGDRTGEGTA 237 567899999****************999999998877766 PP == domain 4 score: 0.3 bits; conditional E-value: 1.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLek 62 y+ +G++ + L+d +++++ ++ l+ + ++ FUN_002327-T1 238 YGNLGNAYESLSDFRKAIEYHEKHLEIAIEVGN 270 444555555555555555555555554444444 PP == domain 5 score: 0.6 bits; conditional E-value: 1.1 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd +++++ ++ l+ + ++ + +G FUN_002327-T1 278 YGYLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNRVGQG 315 78899999999999999999999888777777766666 PP == domain 6 score: -1.5 bits; conditional E-value: 5.1 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkee 57 y+ G + + Lgdl+++++ ++ lk FUN_002327-T1 318 YGNFGIAYRSLGDLRKAIEYHEKHLKIA 345 5667888999******999998888755 PP == domain 7 score: -1.4 bits; conditional E-value: 4.6 CODH_A_N 31 altGekvktLgdleevLnrarsllkeelkLekaldaGm 68 + G+ + Lgd +++++ ++ l+ + ++ + +G FUN_002327-T1 359 GSFGNTYQSLGDFRKAIEYHEKHLEIAIEVGNWVGKGN 396 66788999999999999999999888777776666665 PP == domain 8 score: 1.5 bits; conditional E-value: 0.57 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd++++++ ++ lk + ++ + G FUN_002327-T1 398 YGNLGNAYQSLGDVRKAIEYHEKHLKIAIEVGHRVGEG 435 56677888888888888888888777776665555554 PP == domain 9 score: 0.2 bits; conditional E-value: 1.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLe 61 y+ +G + + Lgdl+++++ ++ l+ + + FUN_002327-T1 478 YGSLGSAYRSLGDLRKAIEYHEKHLEIAIEVG 509 67788888999999999988888777665544 PP == domain 10 score: -1.0 bits; conditional E-value: 3.6 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGm 68 y+ +G + + Lgd +++++ ++ + e + ++ G+ FUN_002327-T1 558 YGNLGIAYQSLGDFRKAIEYHEKHSEIEREVGDRTGEGT 596 6778999999****9999998887777777776665555 PP == domain 11 score: -2.0 bits; conditional E-value: 6.9 CODH_A_N 37 vktLgdleevLnrarsllkeelk.Lekalda 66 +Lg++ +L r++++ ++k Le a++ FUN_002327-T1 638 YGNLGNAYYLLGDFRKAIEYHEKhLEIAIEV 668 5556666666666666665555444444433 PP == domain 12 score: -0.5 bits; conditional E-value: 2.5 CODH_A_N 36 kvktLgdleevLnrarsllkeelk.Lekalda 66 + +Lg++ ++L r++++ ++k Le a++ FUN_002327-T1 717 AYGNLGNAYQLLGDFRKAIEYHEKqLEIAIEV 748 55666777777777777666555445555544 PP == domain 13 score: -0.5 bits; conditional E-value: 2.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd +++++ ++ l+ + ++ + G FUN_002327-T1 758 YGSLGRAYQSLGDFRKAIEYHEKDLEIAIEVGNRFGEG 795 67789999999999999999988887777766666655 PP == domain 14 score: 0.3 bits; conditional E-value: 1.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd +++++ ++ l+ ++ ++ + G FUN_002327-T1 798 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVGDRVGEG 835 56677888888888888888888777777666666555 PP >> DUF1965 Domain of unknown function (DUF1965) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 1.1 8.5e+02 35 47 .. 45 57 .. 37 67 .. 0.83 2 ? -0.7 0.0 2.2 1.7e+03 32 47 .. 162 177 .. 156 187 .. 0.84 3 ? 1.8 0.0 0.38 2.9e+02 32 47 .. 202 217 .. 196 227 .. 0.83 4 ? 3.1 0.0 0.15 1.1e+02 32 47 .. 242 257 .. 234 267 .. 0.84 5 ? 3.4 0.0 0.12 90 30 47 .. 280 297 .. 276 307 .. 0.86 6 ? -2.5 0.0 8.5 6.4e+03 32 48 .. 322 338 .. 319 351 .. 0.81 7 ? 4.4 0.0 0.058 44 27 61 .. 357 391 .. 340 397 .. 0.76 8 ? -2.6 0.0 8.7 6.5e+03 32 47 .. 402 417 .. 385 423 .. 0.75 9 ? -0.8 0.0 2.4 1.8e+03 32 47 .. 522 537 .. 516 546 .. 0.84 10 ? 1.6 0.0 0.43 3.2e+02 32 47 .. 562 577 .. 555 591 .. 0.83 11 ? -0.7 0.0 2.2 1.7e+03 32 46 .. 602 616 .. 595 627 .. 0.82 12 ? -1.7 0.0 4.6 3.5e+03 33 48 .. 723 738 .. 718 749 .. 0.81 13 ? 0.9 0.0 0.71 5.3e+02 32 47 .. 762 777 .. 755 785 .. 0.84 14 ? 1.5 0.0 0.46 3.4e+02 32 47 .. 802 817 .. 796 829 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 1.1 DUF1965 35 YetteeFRaaies 47 +++ ++FR+ai+ FUN_002327-T1 45 FQSLDDFRKAIKY 57 6899******985 PP == domain 2 score: -0.7 bits; conditional E-value: 2.2 DUF1965 32 gkfYetteeFRaaies 47 g+ Y++ eFR++ie FUN_002327-T1 162 GNAYRSLGEFRKGIEY 177 677*********9975 PP == domain 3 score: 1.8 bits; conditional E-value: 0.38 DUF1965 32 gkfYetteeFRaaies 47 g+ Y++ +FR+aie FUN_002327-T1 202 GITYQSLGDFRKAIEY 217 778**********985 PP == domain 4 score: 3.1 bits; conditional E-value: 0.15 DUF1965 32 gkfYetteeFRaaies 47 g+ Ye+ +FR+aie FUN_002327-T1 242 GNAYESLSDFRKAIEY 257 678**********985 PP == domain 5 score: 3.4 bits; conditional E-value: 0.12 DUF1965 30 yngkfYetteeFRaaies 47 y g+ Y++ +FR+aie FUN_002327-T1 280 YLGNAYQSLGDFRKAIEY 297 88999**********985 PP == domain 6 score: -2.5 bits; conditional E-value: 8.5 DUF1965 32 gkfYetteeFRaaiesp 48 g+ Y++ ++R+aie FUN_002327-T1 322 GIAYRSLGDLRKAIEYH 338 56799********9865 PP == domain 7 score: 4.4 bits; conditional E-value: 0.058 DUF1965 27 GwlyngkfYetteeFRaaiespgfkklgpnvd.geW 61 G+ + g+ Y++ +FR+aie + k l+ ++ g+W FUN_002327-T1 357 GYGSFGNTYQSLGDFRKAIEYHE-KHLEIAIEvGNW 391 56667899***********9887.566555554666 PP == domain 8 score: -2.6 bits; conditional E-value: 8.7 DUF1965 32 gkfYetteeFRaaies 47 g+ Y++ + R+aie FUN_002327-T1 402 GNAYQSLGDVRKAIEY 417 5789999999999975 PP == domain 9 score: -0.8 bits; conditional E-value: 2.4 DUF1965 32 gkfYetteeFRaaies 47 g+ Y++ eFR++ie FUN_002327-T1 522 GNAYRSLGEFRKGIEY 537 677*********9975 PP == domain 10 score: 1.6 bits; conditional E-value: 0.43 DUF1965 32 gkfYetteeFRaaies 47 g+ Y++ +FR+aie FUN_002327-T1 562 GIAYQSLGDFRKAIEY 577 677**********985 PP == domain 11 score: -0.7 bits; conditional E-value: 2.2 DUF1965 32 gkfYetteeFRaaie 46 g+ Y++ +FR+a e FUN_002327-T1 602 GNAYQSLGDFRKANE 616 677*********965 PP == domain 12 score: -1.7 bits; conditional E-value: 4.6 DUF1965 33 kfYetteeFRaaiesp 48 + Y+ +FR+aie FUN_002327-T1 723 NAYQLLGDFRKAIEYH 738 6688899*****9865 PP == domain 13 score: 0.9 bits; conditional E-value: 0.71 DUF1965 32 gkfYetteeFRaaies 47 g Y++ +FR+aie FUN_002327-T1 762 GRAYQSLGDFRKAIEY 777 567**********975 PP == domain 14 score: 1.5 bits; conditional E-value: 0.46 DUF1965 32 gkfYetteeFRaaies 47 g+ Y++ +FR+aie FUN_002327-T1 802 GNAYQSLGDFRKAIEY 817 677**********985 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 1.4 1e+03 3 24 .. 78 99 .. 77 100 .. 0.85 2 ? 0.2 0.0 2.1 1.6e+03 4 24 .. 119 139 .. 117 140 .. 0.81 3 ? 0.5 0.0 1.8 1.3e+03 2 24 .. 157 179 .. 156 180 .. 0.90 4 ? 0.2 0.0 2.3 1.7e+03 2 24 .. 237 259 .. 236 260 .. 0.86 5 ? 2.2 0.0 0.51 3.9e+02 3 24 .. 278 299 .. 276 300 .. 0.85 6 ? 0.3 0.0 2 1.5e+03 9 24 .. 324 339 .. 318 340 .. 0.89 7 ? -1.4 0.0 6.9 5.2e+03 11 24 .. 366 379 .. 358 380 .. 0.81 8 ? 2.6 0.0 0.38 2.8e+02 3 24 .. 398 419 .. 397 420 .. 0.87 9 ? 2.9 0.1 0.3 2.2e+02 3 24 .. 438 459 .. 437 460 .. 0.88 10 ? 6.1 0.0 0.029 22 2 24 .. 477 499 .. 476 500 .. 0.91 11 ? 1.3 0.0 0.94 7.1e+02 2 24 .. 517 539 .. 516 540 .. 0.91 12 ? 0.5 0.0 1.7 1.3e+03 3 24 .. 558 579 .. 556 580 .. 0.80 13 ? 0.9 0.0 1.3 9.8e+02 2 24 .. 597 619 .. 596 620 .. 0.86 14 ? 2.9 0.1 0.3 2.2e+02 3 24 .. 638 659 .. 637 660 .. 0.88 15 ? 2.0 0.0 0.56 4.2e+02 2 24 .. 677 699 .. 676 700 .. 0.87 16 ? 0.8 0.0 1.4 1.1e+03 3 24 .. 718 739 .. 717 740 .. 0.85 17 ? 3.6 0.0 0.18 1.4e+02 3 24 .. 758 779 .. 757 780 .. 0.90 18 ? 2.5 0.0 0.39 2.9e+02 3 24 .. 798 819 .. 797 820 .. 0.87 19 ? 0.7 0.0 1.5 1.1e+03 2 23 .. 837 858 .. 836 868 .. 0.83 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 1.4 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y G++++A+e+++ FUN_002327-T1 78 YGNLGNAYQLLGDVRKAIEYHE 99 77777999999*******9987 PP == domain 2 score: 0.2 bits; conditional E-value: 2.1 PPR 4 nslIsgycknGkleeAlelfk 24 l ++y G++++A+e+++ FUN_002327-T1 119 RNLGNAYQLLGDVRKAIEYHE 139 5666889999********987 PP == domain 3 score: 0.5 bits; conditional E-value: 1.8 PPR 2 tynslIsgycknGkleeAlelfk 24 ty l ++y + G++++ +e+++ FUN_002327-T1 157 TYRNLGNAYRSLGEFRKGIEYHE 179 888999************99887 PP == domain 4 score: 0.2 bits; conditional E-value: 2.3 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + ++++A+e+++ FUN_002327-T1 237 AYGNLGNAYESLSDFRKAIEYHE 259 58888899***********9987 PP == domain 5 score: 2.2 bits; conditional E-value: 0.51 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002327-T1 278 YGYLGNAYQSLGDFRKAIEYHE 299 6777799************987 PP == domain 6 score: 0.3 bits; conditional E-value: 2 PPR 9 gycknGkleeAlelfk 24 +y + G+l++A+e+++ FUN_002327-T1 324 AYRSLGDLRKAIEYHE 339 78999********987 PP == domain 7 score: -1.4 bits; conditional E-value: 6.9 PPR 11 cknGkleeAlelfk 24 + G++++A+e+++ FUN_002327-T1 366 QSLGDFRKAIEYHE 379 578*******9987 PP == domain 8 score: 2.6 bits; conditional E-value: 0.38 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002327-T1 398 YGNLGNAYQSLGDVRKAIEYHE 419 777889*************987 PP == domain 9 score: 2.9 bits; conditional E-value: 0.3 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y G++++A+e+++ FUN_002327-T1 438 YGNLGNAYYLLGDFRKAIEYHE 459 778889*************987 PP == domain 10 score: 6.1 bits; conditional E-value: 0.029 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl s+y + G+l++A+e+++ FUN_002327-T1 477 AYGSLGSAYRSLGDLRKAIEYHE 499 799*****************987 PP == domain 11 score: 1.3 bits; conditional E-value: 0.94 PPR 2 tynslIsgycknGkleeAlelfk 24 ty l ++y + G++++ +e+++ FUN_002327-T1 517 TYGNLGNAYRSLGEFRKGIEYHE 539 899999************99887 PP == domain 12 score: 0.5 bits; conditional E-value: 1.7 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +y + G++++A+e+++ FUN_002327-T1 558 YGNLGIAYQSLGDFRKAIEYHE 579 56666689999********987 PP == domain 13 score: 0.9 bits; conditional E-value: 1.3 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A e+++ FUN_002327-T1 597 AYGNLGNAYQSLGDFRKANEYHE 619 5888889***********99876 PP == domain 14 score: 2.9 bits; conditional E-value: 0.3 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y G++++A+e+++ FUN_002327-T1 638 YGNLGNAYYLLGDFRKAIEYHE 659 778889*************987 PP == domain 15 score: 2.0 bits; conditional E-value: 0.56 PPR 2 tynslIsgycknGkleeAlelfk 24 +y s s+y + G+ ++A+e+++ FUN_002327-T1 677 AYGSFGSAYRSLGDSRKAIEYHE 699 5778889*************987 PP == domain 16 score: 0.8 bits; conditional E-value: 1.4 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y G++++A+e+++ FUN_002327-T1 718 YGNLGNAYQLLGDFRKAIEYHE 739 77777999999*******9987 PP == domain 17 score: 3.6 bits; conditional E-value: 0.18 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002327-T1 758 YGSLGRAYQSLGDFRKAIEYHE 779 89999**************987 PP == domain 18 score: 2.5 bits; conditional E-value: 0.39 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002327-T1 798 YGNLGNAYQSLGDFRKAIEYHE 819 777889*************987 PP == domain 19 score: 0.7 bits; conditional E-value: 1.5 PPR 2 tynslIsgycknGkleeAlelf 23 ty + y + G++e Al +f FUN_002327-T1 837 TYHNMGGEYFSLGQFEIALGMF 858 7777888899999999999998 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 2.5 1.8e+03 104 129 .. 80 105 .. 46 147 .. 0.52 2 ? 0.8 0.0 0.51 3.8e+02 76 115 .. 139 178 .. 102 228 .. 0.62 3 ? -0.3 0.0 1 7.8e+02 105 170 .. 201 264 .. 192 275 .. 0.59 4 ? -0.3 0.0 1.1 8.3e+02 115 170 .. 251 304 .. 211 317 .. 0.55 5 ? -1.5 0.0 2.4 1.8e+03 122 129 .. 338 345 .. 279 393 .. 0.52 6 ? -1.7 0.0 2.9 2.2e+03 114 169 .. 403 463 .. 372 475 .. 0.52 7 ? -0.5 0.0 1.2 9e+02 100 128 .. 476 504 .. 445 548 .. 0.75 8 ? -0.5 0.0 1.3 9.6e+02 107 170 .. 563 624 .. 536 631 .. 0.62 9 ? 3.2 0.0 0.092 69 100 171 .. 716 785 .. 693 796 .. 0.82 10 ? 4.1 0.0 0.048 36 102 171 .. 798 865 .. 790 870 .. 0.62 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 2.5 TPR_NPHP3 104 alGrflkdlgllsqalpaLqraLeiR 129 lG+ + lg + +a++ ++ Lei FUN_002327-T1 80 NLGNAYQLLGDVRKAIEYHEKHLEIA 105 44444455555555554444444442 PP == domain 2 score: 0.8 bits; conditional E-value: 0.51 TPR_NPHP3 76 kaYlnaikkledavegeltlakvadlyealGrflkdlgll 115 +++l+ + ++ d v++ t ++ + y +lG+f k + FUN_002327-T1 139 EKHLEIAIEVGDRVGEGGTYRNLGNAYRSLGEFRKGIEYH 178 4455555556666666666666666666666666655443 PP == domain 3 score: -0.3 bits; conditional E-value: 1 TPR_NPHP3 105 lGrflkdlgllsqalpaLqraLei.RetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 lG + lg +a++ ++ Lei Re D + ++ +L + y+ f++a +++++ lei FUN_002327-T1 201 LGITYQSLGDFRKAIEYHEKHLEIeREI---GDRTGEGTAYGNLGNAYESLSDFRKAIEYHEKHLEI 264 4444444444444444444444442222...244555566677777777777777777777777776 PP == domain 4 score: -0.3 bits; conditional E-value: 1.1 TPR_NPHP3 115 lsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 +a++ ++ Lei + + ++++ +L + y+ g f++a +++++ lei FUN_002327-T1 251 FRKAIEYHEKHLEIAIEV--GNRVGEGSAYGYLGNAYQSLGDFRKAIEYHEKHLEI 304 333333333333332222..111222344556666666666666666666666665 PP == domain 5 score: -1.5 bits; conditional E-value: 2.4 TPR_NPHP3 122 LqraLeiR 129 ++ L i FUN_002327-T1 338 HEKHLKIA 345 33333333 PP == domain 6 score: -1.7 bits; conditional E-value: 2.9 TPR_NPHP3 114 llsqalpaLqraLeiRetal....dPDhPl.varslhqLagLyaqwgkfstaealykqale 169 q+l +++a+e e l + h + ++++ +L + y g f++a +++++ le FUN_002327-T1 403 NAYQSLGDVRKAIEYHEKHLkiaiEVGHRVgEGNAYGNLGNAYYLLGDFRKAIEYHEKHLE 463 3333444444444444333200002233221233444455555555555555555555554 PP == domain 7 score: -0.5 bits; conditional E-value: 1.2 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLei 128 + y +lG + lg l +a++ ++ Lei FUN_002327-T1 476 SAYGSLGSAYRSLGDLRKAIEYHEKHLEI 504 56778888888888888888887777777 PP == domain 8 score: -0.5 bits; conditional E-value: 1.3 TPR_NPHP3 107 rflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 + lg +a++ ++ ei + D + ++ +L + y+ g f++a++++++ l+i FUN_002327-T1 563 IAYQSLGDFRKAIEYHEKHSEIEREV--GDRTGEGTAYGNLGNAYQSLGDFRKANEYHEKHLKI 624 44444444444444444444442222..344455566667777777777777777777777766 PP == domain 9 score: 3.2 bits; conditional E-value: 0.092 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 + y lG+ + lg +a++ ++ Lei + d D ++++ L + y+ g f++a +++++ lei FUN_002327-T1 716 NAYGNLGNAYQLLGDFRKAIEYHEKQLEIAIEVGDRDG--EGNAYGSLGRAYQSLGDFRKAIEYHEKDLEIA 785 67888999999999999999999999999888877776..47888999999999999999999999999985 PP == domain 10 score: 4.1 bits; conditional E-value: 0.048 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 y lG+ + lg +a++ ++ Lei + D + ++h++ g y g+f+ a ++ a++++ FUN_002327-T1 798 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--GDRVGEGITYHNMGGEYFSLGQFEIALGMFVSAVKVF 865 5556666666666666666666666665555..3444445566777777777777777776666666655 PP >> Rhodanese Rhodanese-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.23 1.7e+02 15 36 .. 87 108 .. 75 121 .. 0.77 2 ? 4.5 0.0 0.086 65 11 37 .. 123 153 .. 114 196 .. 0.74 3 ? 0.7 0.0 1.3 9.8e+02 16 37 .. 248 271 .. 236 296 .. 0.76 4 ? -0.4 0.0 2.9 2.2e+03 16 36 .. 288 308 .. 278 321 .. 0.80 5 ? 2.0 0.0 0.51 3.9e+02 16 37 .. 328 351 .. 317 375 .. 0.77 6 ? -0.4 0.0 2.9 2.2e+03 16 37 .. 368 391 .. 361 404 .. 0.79 7 ? 4.0 0.0 0.13 96 16 36 .. 408 428 .. 394 445 .. 0.78 8 ? 0.5 0.0 1.5 1.1e+03 14 37 .. 446 471 .. 435 501 .. 0.74 9 ? 0.7 0.0 1.3 9.9e+02 16 37 .. 488 511 .. 476 536 .. 0.78 10 ? 4.7 0.0 0.076 57 16 37 .. 608 631 .. 596 654 .. 0.79 11 ? -0.2 0.0 2.5 1.9e+03 14 36 .. 646 668 .. 635 681 .. 0.79 12 ? 0.3 0.0 1.8 1.4e+03 17 37 .. 689 711 .. 682 743 .. 0.73 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.23 Rhodanese 15 vliDvRppeeyakghIpgAvnv 36 +l DvR + ey + h++ A+ v FUN_002327-T1 87 LLGDVRKAIEYHEKHLEIAIEV 108 388*****************99 PP == domain 2 score: 4.5 bits; conditional E-value: 0.086 Rhodanese 11 dgkvvliDvRppeeyakghIpgAvnv....s 37 + +l DvR + ey + h++ A+ v FUN_002327-T1 123 NAYQLLGDVRKAIEYHEKHLEIAIEVgdrvG 153 4433488*****************9964440 PP == domain 3 score: 0.7 bits; conditional E-value: 1.3 Rhodanese 16 liDvRppeeyakghIpgAvnv..s 37 l D R + ey + h++ A+ v + FUN_002327-T1 248 LSDFRKAIEYHEKHLEIAIEVgnR 271 88*****************99441 PP == domain 4 score: -0.4 bits; conditional E-value: 2.9 Rhodanese 16 liDvRppeeyakghIpgAvnv 36 l D R + ey + h++ A+ v FUN_002327-T1 288 LGDFRKAIEYHEKHLEIAIEV 308 6799***************99 PP == domain 5 score: 2.0 bits; conditional E-value: 0.51 Rhodanese 16 liDvRppeeyakghIpgAvnv..s 37 l D+R + ey + h++ A+ v + FUN_002327-T1 328 LGDLRKAIEYHEKHLKIAIEVgdR 351 569******************431 PP == domain 6 score: -0.4 bits; conditional E-value: 2.9 Rhodanese 16 liDvRppeeyakghIpgAvnv..s 37 l D R + ey + h++ A+ v + FUN_002327-T1 368 LGDFRKAIEYHEKHLEIAIEVgnW 391 6699***************99443 PP == domain 7 score: 4.0 bits; conditional E-value: 0.13 Rhodanese 16 liDvRppeeyakghIpgAvnv 36 l DvR + ey + h++ A+ v FUN_002327-T1 408 LGDVRKAIEYHEKHLKIAIEV 428 88*****************99 PP == domain 8 score: 0.5 bits; conditional E-value: 1.5 Rhodanese 14 vvliDvRppeeyakghIpgAvnv..s 37 ++l D R + ey + h++ A+ v + FUN_002327-T1 446 YLLGDFRKAIEYHEKHLEIAIEVgdR 471 557799***************99541 PP == domain 9 score: 0.7 bits; conditional E-value: 1.3 Rhodanese 16 liDvRppeeyakghIpgAvnv..s 37 l D+R + ey + h++ A+ v + FUN_002327-T1 488 LGDLRKAIEYHEKHLEIAIEVgnR 511 669****************99541 PP == domain 10 score: 4.7 bits; conditional E-value: 0.076 Rhodanese 16 liDvRppeeyakghIpgAvnv..s 37 l D R ++ey + h++ A+ v + FUN_002327-T1 608 LGDFRKANEYHEKHLKIAIEVgdR 631 78*****************99442 PP == domain 11 score: -0.2 bits; conditional E-value: 2.5 Rhodanese 14 vvliDvRppeeyakghIpgAvnv 36 ++l D R + ey + h++ A+ v FUN_002327-T1 646 YLLGDFRKAIEYHEKHLEIAIEV 668 55779***************999 PP == domain 12 score: 0.3 bits; conditional E-value: 1.8 Rhodanese 17 iDvRppeeyakghIpgAvnv..s 37 D R + ey + h++ A+ v + FUN_002327-T1 689 GDSRKAIEYHEKHLEIAIEVgkR 711 59999**************9431 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.6 1.2e+03 25 46 .. 75 96 .. 49 106 .. 0.80 2 ? -0.9 0.0 4 3e+03 26 46 .. 116 136 .. 111 143 .. 0.85 3 ? 0.4 0.0 1.6 1.2e+03 5 46 .. 209 256 .. 205 265 .. 0.78 4 ? -0.1 0.0 2.3 1.7e+03 27 46 .. 277 296 .. 273 305 .. 0.79 5 ? -1.5 0.0 6 4.5e+03 5 45 .. 289 335 .. 286 337 .. 0.56 6 ? 2.6 0.0 0.33 2.5e+02 5 46 .. 369 416 .. 366 424 .. 0.74 7 ? 2.6 0.0 0.31 2.4e+02 26 46 .. 436 456 .. 432 464 .. 0.88 8 ? -0.4 0.0 2.8 2.1e+03 27 46 .. 557 576 .. 555 590 .. 0.81 9 ? 1.5 0.0 0.72 5.4e+02 5 44 .. 569 614 .. 565 617 .. 0.75 10 ? 3.3 0.1 0.2 1.5e+02 24 46 .. 634 656 .. 607 663 .. 0.79 11 ? 2.0 0.1 0.5 3.8e+02 21 46 .. 711 736 .. 688 745 .. 0.77 12 ? 5.6 0.1 0.036 27 5 46 .. 729 776 .. 726 784 .. 0.89 13 ? 1.7 0.0 0.64 4.8e+02 26 46 .. 796 816 .. 793 827 .. 0.83 14 ? -1.1 0.1 4.8 3.6e+03 33 55 .. 895 917 .. 895 928 .. 0.83 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.6 TPR_19 25 aearllLArallalgrldeAea 46 a+ +L++a+ lg++ +A++ FUN_002327-T1 75 GNAYGNLGNAYQLLGDVRKAIE 96 5688889999999999999986 PP == domain 2 score: -0.9 bits; conditional E-value: 4 TPR_19 26 earllLArallalgrldeAea 46 a+ +L++a+ lg++ +A++ FUN_002327-T1 116 NAYRNLGNAYQLLGDVRKAIE 136 578899999999999999986 PP == domain 3 score: 0.4 bits; conditional E-value: 1.6 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ l ++ +A++ FUN_002327-T1 209 GDFRKAIEYHEKHLEIEREigdrtgEGTAYGNLGNAYESLSDFRKAIE 256 899999999999888866655555688888888888888888888876 PP == domain 4 score: -0.1 bits; conditional E-value: 2.3 TPR_19 27 arllLArallalgrldeAea 46 a+ L++a+ lg++ +A++ FUN_002327-T1 277 AYGYLGNAYQSLGDFRKAIE 296 56678899999999999986 PP == domain 5 score: -1.5 bits; conditional E-value: 6 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAe 45 gd+ +A+++ e+ l+++ + a+ + + a+ lg+l +A+ FUN_002327-T1 289 GDFRKAIEYHEKHLEIAIEvgnrvgQGNAYGNFGIAYRSLGDLRKAI 335 77777777777755442222222335566666666666666666665 PP == domain 6 score: 2.6 bits; conditional E-value: 0.33 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002327-T1 369 GDFRKAIEYHEKHLEIAIEvgnwvgKGNAYGNLGNAYQSLGDVRKAIE 416 7777777777775555333333355889999*************9987 PP == domain 7 score: 2.6 bits; conditional E-value: 0.31 TPR_19 26 earllLArallalgrldeAea 46 a+ +L++a++ lg++ +A++ FUN_002327-T1 436 NAYGNLGNAYYLLGDFRKAIE 456 68899**************87 PP == domain 8 score: -0.4 bits; conditional E-value: 2.8 TPR_19 27 arllLArallalgrldeAea 46 a+ +L+ a+ lg++ +A++ FUN_002327-T1 557 AYGNLGIAYQSLGDFRKAIE 576 66788999999999999987 PP == domain 9 score: 1.5 bits; conditional E-value: 0.72 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeA 44 gd+ +A+++ e+ +++ + a+ +L++a+ lg++ +A FUN_002327-T1 569 GDFRKAIEYHEKHSEIEREvgdrtgEGTAYGNLGNAYQSLGDFRKA 614 7888888888886555444444444889999***********9998 PP == domain 10 score: 3.3 bits; conditional E-value: 0.2 TPR_19 24 naearllLArallalgrldeAea 46 a+ +L++a++ lg++ +A++ FUN_002327-T1 634 EGNAYGNLGNAYYLLGDFRKAIE 656 568999***************87 PP == domain 11 score: 2.0 bits; conditional E-value: 0.5 TPR_19 21 dPdnaearllLArallalgrldeAea 46 + a+ +L++a+ lg++ +A++ FUN_002327-T1 711 REGEGNAYGNLGNAYQLLGDFRKAIE 736 55677899999999999999999987 PP == domain 12 score: 5.6 bits; conditional E-value: 0.036 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + a+ L+ra+ lg++ +A++ FUN_002327-T1 729 GDFRKAIEYHEKQLEIaievgdRDGEGNAYGSLGRAYQSLGDFRKAIE 776 9999********99888888856669********************87 PP == domain 13 score: 1.7 bits; conditional E-value: 0.64 TPR_19 26 earllLArallalgrldeAea 46 a+ +L++a+ lg++ +A++ FUN_002327-T1 796 NAYGNLGNAYQSLGDFRKAIE 816 688899999999999999987 PP == domain 14 score: -1.1 bits; conditional E-value: 4.8 TPR_19 33 rallalgrldeAealLaalpaad 55 r+ll+ g+ deA ++++a+ FUN_002327-T1 895 RLLLRIGKTDEALFAADQGRAQT 917 68999999999999988888876 PP >> DUF6225 Family of unknown function (DUF6225) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 6 4.5e+03 17 46 .. 51 80 .. 44 82 .. 0.88 2 ? -1.2 0.0 4.1 3.1e+03 15 46 .. 129 160 .. 123 162 .. 0.89 3 ? -2.0 0.0 7.2 5.4e+03 27 46 .. 181 200 .. 167 206 .. 0.79 4 ? -1.4 0.0 4.8 3.6e+03 15 47 .. 289 321 .. 286 325 .. 0.87 5 ? 3.5 0.0 0.13 1e+02 15 47 .. 329 361 .. 324 364 .. 0.92 6 ? -1.1 0.0 3.8 2.9e+03 15 45 .. 489 519 .. 486 522 .. 0.90 7 ? -1.6 0.0 5.5 4.1e+03 15 47 .. 649 681 .. 644 683 .. 0.87 8 ? -1.1 0.0 3.7 2.8e+03 15 45 .. 729 759 .. 723 761 .. 0.88 9 ? -0.3 0.0 2.1 1.5e+03 15 46 .. 769 800 .. 765 803 .. 0.91 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 6 DUF6225 17 LRealkgLPDdtPihvgvaddPGdfdgyee 46 R+a+k + i ++v d G++++y + FUN_002327-T1 51 FRKAIKYHEKHLEIAIEVGDRVGEGNAYGN 80 6888888889999************99975 PP == domain 2 score: -1.2 bits; conditional E-value: 4.1 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyee 46 g +R+a++ + i ++v d G++ +y++ FUN_002327-T1 129 GDVRKAIEYHEKHLEIAIEVGDRVGEGGTYRN 160 668999999999999************99986 PP == domain 3 score: -2.0 bits; conditional E-value: 7.2 DUF6225 27 dtPihvgvaddPGdfdgyee 46 + i ++v d G++ gy + FUN_002327-T1 181 HLKIAIEVGDRAGEGSGYGN 200 56799************986 PP == domain 4 score: -1.4 bits; conditional E-value: 4.8 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyeey 47 g R+a++ + i ++v + G++++y ++ FUN_002327-T1 289 GDFRKAIEYHEKHLEIAIEVGNRVGQGNAYGNF 321 678999999999999***************988 PP == domain 5 score: 3.5 bits; conditional E-value: 0.13 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyeey 47 g LR+a++ + i ++v d G+++gy + FUN_002327-T1 329 GDLRKAIEYHEKHLKIAIEVGDRDGEGNGYGSF 361 88****************************876 PP == domain 6 score: -1.1 bits; conditional E-value: 3.8 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgye 45 g LR+a++ + i ++v + G++ +y FUN_002327-T1 489 GDLRKAIEYHEKHLEIAIEVGNRVGEGGTYG 519 789**********************999997 PP == domain 7 score: -1.6 bits; conditional E-value: 5.5 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyeey 47 g R+a++ + i ++v d G++ +y + FUN_002327-T1 649 GDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGSF 681 678999999999999***********9999765 PP == domain 8 score: -1.1 bits; conditional E-value: 3.7 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgye 45 g R+a++ ++ i ++v d G++++y FUN_002327-T1 729 GDFRKAIEYHEKQLEIAIEVGDRDGEGNAYG 759 667999999999999***********99996 PP == domain 9 score: -0.3 bits; conditional E-value: 2.1 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyee 46 g R+a++ d+ i ++v + G++++y + FUN_002327-T1 769 GDFRKAIEYHEKDLEIAIEVGNRFGEGNAYGN 800 77899**********************99975 PP >> RCF1-5-like_lid RCF1/5-like, AAA+ ATPase lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.057 43 23 35 .. 323 335 .. 322 339 .. 0.92 2 ? 2.0 0.0 0.39 2.9e+02 26 35 .. 486 495 .. 484 499 .. 0.86 3 ? 0.5 0.0 1.1 8.5e+02 23 35 .. 563 575 .. 561 579 .. 0.92 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.057 RCF1-5-like_lid 23 IakkSnGNLRrAl 35 Ia +S G+LR+A+ FUN_002327-T1 323 IAYRSLGDLRKAI 335 899*********8 PP == domain 2 score: 2.0 bits; conditional E-value: 0.39 RCF1-5-like_lid 26 kSnGNLRrAl 35 +S G+LR+A+ FUN_002327-T1 486 RSLGDLRKAI 495 799******8 PP == domain 3 score: 0.5 bits; conditional E-value: 1.1 RCF1-5-like_lid 23 IakkSnGNLRrAl 35 Ia +S G+ R+A+ FUN_002327-T1 563 IAYQSLGDFRKAI 575 999*********8 PP >> ANAPC3 Anaphase-promoting complex, cyclosome, subunit 3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.2 9.2e+02 26 49 .. 77 101 .. 47 108 .. 0.66 2 ? -0.3 0.1 2.5 1.9e+03 29 49 .. 121 141 .. 98 147 .. 0.85 3 ? 0.1 0.0 2 1.5e+03 32 54 .. 204 226 .. 201 254 .. 0.83 4 ? 3.6 0.1 0.16 1.2e+02 27 49 .. 279 301 .. 247 308 .. 0.73 5 ? 0.5 0.0 1.4 1.1e+03 30 49 .. 362 381 .. 331 390 .. 0.87 6 ? -0.3 0.0 2.6 2e+03 29 50 .. 401 423 .. 395 428 .. 0.83 7 ? 4.6 0.2 0.079 59 29 49 .. 441 461 .. 410 467 .. 0.84 8 ? -0.6 0.0 3.3 2.5e+03 29 49 .. 481 501 .. 474 507 .. 0.82 9 ? 0.4 0.0 1.6 1.2e+03 32 53 .. 564 585 .. 554 593 .. 0.81 10 ? -1.5 0.0 5.9 4.5e+03 29 49 .. 601 621 .. 596 632 .. 0.83 11 ? 4.7 0.1 0.073 55 29 49 .. 641 661 .. 618 667 .. 0.82 12 ? 1.6 0.0 0.66 4.9e+02 21 49 .. 712 741 .. 687 747 .. 0.70 13 ? 1.8 0.0 0.58 4.3e+02 26 49 .. 758 781 .. 728 788 .. 0.69 14 ? 1.8 0.0 0.56 4.2e+02 29 50 .. 801 822 .. 793 832 .. 0.81 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.2 ANAPC3 26 ayl.lAqclflngqykrAyellrka 49 ay l++++ l+g+ ++A+e+ +k+ FUN_002327-T1 77 AYGnLGNAYQLLGDVRKAIEYHEKH 101 44337999***********998887 PP == domain 2 score: -0.3 bits; conditional E-value: 2.5 ANAPC3 29 lAqclflngqykrAyellrka 49 l++++ l+g+ ++A+e+ +k+ FUN_002327-T1 121 LGNAYQLLGDVRKAIEYHEKH 141 689999*********998887 PP == domain 3 score: 0.1 bits; conditional E-value: 2 ANAPC3 32 clflngqykrAyellrkaklnek 54 ++ ++g++++A+e+ +k+ + e+ FUN_002327-T1 204 TYQSLGDFRKAIEYHEKHLEIER 226 68999********9999955555 PP == domain 4 score: 3.6 bits; conditional E-value: 0.16 ANAPC3 27 yllAqclflngqykrAyellrka 49 +l++++ ++g++++A+e+ +k+ FUN_002327-T1 279 GYLGNAYQSLGDFRKAIEYHEKH 301 356***************99888 PP == domain 5 score: 0.5 bits; conditional E-value: 1.4 ANAPC3 30 AqclflngqykrAyellrka 49 ++++ ++g++++A+e+ +k+ FUN_002327-T1 362 GNTYQSLGDFRKAIEYHEKH 381 68999**********98888 PP == domain 6 score: -0.3 bits; conditional E-value: 2.6 ANAPC3 29 lAqclflngqykrAyellrka.k 50 l++++ ++g+ ++A+e+ +k+ k FUN_002327-T1 401 LGNAYQSLGDVRKAIEYHEKHlK 423 688999*********99988844 PP == domain 7 score: 4.6 bits; conditional E-value: 0.079 ANAPC3 29 lAqclflngqykrAyellrka 49 l+++++l+g++++A+e+ +k+ FUN_002327-T1 441 LGNAYYLLGDFRKAIEYHEKH 461 799*************99888 PP == domain 8 score: -0.6 bits; conditional E-value: 3.3 ANAPC3 29 lAqclflngqykrAyellrka 49 l+ +++++g+ ++A+e+ +k+ FUN_002327-T1 481 LGSAYRSLGDLRKAIEYHEKH 501 67899999******9998887 PP == domain 9 score: 0.4 bits; conditional E-value: 1.6 ANAPC3 32 clflngqykrAyellrkaklne 53 ++ ++g++++A+e+ +k+ + e FUN_002327-T1 564 AYQSLGDFRKAIEYHEKHSEIE 585 7999**********99995555 PP == domain 10 score: -1.5 bits; conditional E-value: 5.9 ANAPC3 29 lAqclflngqykrAyellrka 49 l++++ ++g++++A e+ +k+ FUN_002327-T1 601 LGNAYQSLGDFRKANEYHEKH 621 578999999999999988887 PP == domain 11 score: 4.7 bits; conditional E-value: 0.073 ANAPC3 29 lAqclflngqykrAyellrka 49 l+++++l+g++++A+e+ +k+ FUN_002327-T1 641 LGNAYYLLGDFRKAIEYHEKH 661 799*************99888 PP == domain 12 score: 1.6 bits; conditional E-value: 0.66 ANAPC3 21 espedayl.lAqclflngqykrAyellrka 49 e + +ay l++++ l+g++++A+e+ +k FUN_002327-T1 712 EGEGNAYGnLGNAYQLLGDFRKAIEYHEKQ 741 455555554799************997776 PP == domain 13 score: 1.8 bits; conditional E-value: 0.58 ANAPC3 26 ayllAqclflngqykrAyellrka 49 l+ ++ ++g++++A+e+ +k FUN_002327-T1 758 YGSLGRAYQSLGDFRKAIEYHEKD 781 334899************997775 PP == domain 14 score: 1.8 bits; conditional E-value: 0.56 ANAPC3 29 lAqclflngqykrAyellrkak 50 l++++ ++g++++A+e+ +k+ FUN_002327-T1 801 LGNAYQSLGDFRKAIEYHEKHL 822 6899************999983 PP >> NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 9.8 7.4e+03 70 89 .. 54 73 .. 49 105 .. 0.79 2 ? -1.9 0.0 6.8 5.1e+03 70 89 .. 94 113 .. 83 145 .. 0.80 3 ? -1.8 0.0 6.6 5e+03 70 89 .. 414 433 .. 410 449 .. 0.84 4 ? -1.2 0.0 4.4 3.3e+03 58 89 .. 444 473 .. 428 482 .. 0.78 5 ? -1.3 0.0 4.6 3.4e+03 54 89 .. 640 673 .. 620 679 .. 0.79 6 ? 4.3 0.0 0.085 64 70 89 .. 774 793 .. 760 827 .. 0.84 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 9.8 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002327-T1 54 AIKYHEKHLEIAIEVGDRVG 73 799999********999987 PP == domain 2 score: -1.9 bits; conditional E-value: 6.8 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002327-T1 94 AIEYHEKHLEIAIEVGHRVG 113 799999*********99986 PP == domain 3 score: -1.8 bits; conditional E-value: 6.6 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002327-T1 414 AIEYHEKHLKIAIEVGHRVG 433 7999************9987 PP == domain 4 score: -1.2 bits; conditional E-value: 4.4 NAD_binding_11 58 qrvlkrdfepgFaidlllKDlglaldlarelg 89 + l +df + ai+++ K l++a+++++++g FUN_002327-T1 444 AYYLLGDFRK--AIEYHEKHLEIAIEVGDRVG 473 5556666766..79*************99987 PP == domain 5 score: -1.3 bits; conditional E-value: 4.6 NAD_binding_11 54 nklpqrvlkrdfepgFaidlllKDlglaldlarelg 89 n ++ l +df + ai+++ K l++a+++++++g FUN_002327-T1 640 NLGNAYYLLGDFRK--AIEYHEKHLEIAIEVGDRVG 673 55555556667776..799***********999876 PP == domain 6 score: 4.3 bits; conditional E-value: 0.085 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ KDl++a+++++++g FUN_002327-T1 774 AIEYHEKDLEIAIEVGNRFG 793 79*************99987 PP >> Bleomycin_resist_prot_dom Bleomycin resistance protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 8 6e+03 8 35 .. 50 79 .. 47 96 .. 0.79 2 ? 1.2 0.0 0.95 7.1e+02 8 38 .. 210 239 .. 202 253 .. 0.82 3 ? -1.3 0.0 5.4 4e+03 7 37 .. 249 278 .. 242 288 .. 0.81 4 ? 5.2 0.1 0.053 40 8 38 .. 330 359 .. 322 370 .. 0.82 5 ? -2.1 0.0 9.9 7.4e+03 8 34 .. 410 436 .. 403 448 .. 0.82 6 ? -0.3 0.0 2.6 2e+03 3 38 .. 445 479 .. 442 486 .. 0.80 7 ? 0.6 0.0 1.4 1e+03 8 39 .. 490 520 .. 482 527 .. 0.85 8 ? 0.5 0.0 1.6 1.2e+03 3 38 .. 645 682 .. 642 688 .. 0.80 9 ? -0.6 0.0 3.2 2.4e+03 8 37 .. 690 718 .. 682 728 .. 0.80 10 ? 2.4 0.0 0.38 2.9e+02 8 38 .. 730 759 .. 722 768 .. 0.84 11 ? -1.2 0.0 5 3.8e+03 8 35 .. 810 837 .. 802 842 .. 0.86 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 8 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeG..lG 35 d k++k+ ek l ++ r +eG +G FUN_002327-T1 50 DFRKAIKYHEKHLEIAIEVGDRVGEGnaYG 79 78899******9999999999999983334 PP == domain 2 score: 1.2 bits; conditional E-value: 0.95 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l +i r +eG yG FUN_002327-T1 210 DFRKAIEYHEKHLEIEREIGDRTGEGT-AYG 239 889**********************95.233 PP == domain 3 score: -1.3 bits; conditional E-value: 5.4 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGlGdy 37 d k++++ ek l ++ r +eG y FUN_002327-T1 249 SDFRKAIEYHEKHLEIAIEVGNRVGEGS-AY 278 5899***********9999999999994.34 PP == domain 4 score: 5.2 bits; conditional E-value: 0.053 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d+ k++++ ek l ++ rd+eG G yG FUN_002327-T1 330 DLRKAIEYHEKHLKIAIEVGDRDGEGNG-YG 359 899*********************9865.33 PP == domain 5 score: -2.1 bits; conditional E-value: 9.9 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGl 34 d+ k++++ ek l ++ r +eG FUN_002327-T1 410 DVRKAIEYHEKHLKIAIEVGHRVGEGN 436 88999******9999999999999983 PP == domain 6 score: -0.3 bits; conditional E-value: 2.6 Bleomycin_resist_prot_dom 3 vyftkdmdktlkWfekilGWsGdivarddeGlGdyG 38 y d k++++ ek l ++ r +eG yG FUN_002327-T1 445 YYLLGDFRKAIEYHEKHLEIAIEVGDRVGEGS-AYG 479 4667799************9999999999994.344 PP == domain 7 score: 0.6 bits; conditional E-value: 1.4 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyGc 39 d+ k++++ ek l ++ r +eG G yG FUN_002327-T1 490 DLRKAIEYHEKHLEIAIEVGNRVGEG-GTYGN 520 999**********************9.88885 PP == domain 8 score: 0.5 bits; conditional E-value: 1.6 Bleomycin_resist_prot_dom 3 vyftkdmdktlkWfekilGWsGdivarddeG..lGdyG 38 y d k++++ ek l ++ r +eG +G +G FUN_002327-T1 645 YYLLGDFRKAIEYHEKHLEIAIEVGDRVGEGsaYGSFG 682 4667799*************999999999994455555 PP == domain 9 score: -0.6 bits; conditional E-value: 3.2 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdy 37 d k++++ ek l ++ r++eG y FUN_002327-T1 690 DSRKAIEYHEKHLEIAIEVGKREGEGN-AY 718 77899********************94.23 PP == domain 10 score: 2.4 bits; conditional E-value: 0.38 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l ++ rd+eG yG FUN_002327-T1 730 DFRKAIEYHEKQLEIAIEVGDRDGEGN-AYG 759 889**********************94.344 PP == domain 11 score: -1.2 bits; conditional E-value: 5 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlG 35 d k++++ ek l ++ r +eG+ FUN_002327-T1 810 DFRKAIEYHEKHLEIAKEVGDRVGEGIT 837 8899********************9985 PP >> Vps54_N Vacuolar-sorting protein 54, of GARP complex # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.87 6.6e+02 196 218 .. 74 96 .. 52 102 .. 0.83 2 ? 3.2 0.0 0.083 63 177 218 .. 95 136 .. 76 147 .. 0.75 3 ? -2.4 0.0 4.4 3.3e+03 181 218 .. 259 296 .. 236 301 .. 0.69 4 ? -3.3 0.0 8.3 6.2e+03 198 218 .. 396 416 .. 394 432 .. 0.82 5 ? -1.7 0.0 2.7 2e+03 196 218 .. 434 456 .. 403 462 .. 0.77 6 ? -2.5 0.0 4.7 3.5e+03 198 218 .. 636 656 .. 632 667 .. 0.85 7 ? 1.0 0.0 0.41 3.1e+02 184 218 .. 702 736 .. 678 748 .. 0.81 8 ? -2.4 0.0 4.2 3.2e+03 196 218 .. 794 816 .. 766 820 .. 0.81 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.87 Vps54_N 196 dsekYskvleAYkllgktqriad 218 + + Y + +AY+llg++ ++ + FUN_002327-T1 74 EGNAYGNLGNAYQLLGDVRKAIE 96 56889999*********999876 PP == domain 2 score: 3.2 bits; conditional E-value: 0.083 Vps54_N 177 lelveekldsqLsevckeFdsekYskvleAYkllgktqriad 218 +e e++l+ +++ ++ + + Y+ + +AY+llg++ ++ + FUN_002327-T1 95 IEYHEKHLEIAIEVGHRVGEGNAYRNLGNAYQLLGDVRKAIE 136 55556666666666666778899999********99998876 PP == domain 3 score: -2.4 bits; conditional E-value: 4.4 Vps54_N 181 eekldsqLsevckeFdsekYskvleAYkllgktqriad 218 e++l+ +++ ++ + + Y + +AY+ lg++ ++ + FUN_002327-T1 259 EKHLEIAIEVGNRVGEGSAYGYLGNAYQSLGDFRKAIE 296 45555555555555667788889999999999888765 PP == domain 4 score: -3.3 bits; conditional E-value: 8.3 Vps54_N 198 ekYskvleAYkllgktqriad 218 + Y + +AY+ lg++ ++ + FUN_002327-T1 396 NAYGNLGNAYQSLGDVRKAIE 416 67899999*****99999877 PP == domain 5 score: -1.7 bits; conditional E-value: 2.7 Vps54_N 196 dsekYskvleAYkllgktqriad 218 + + Y + +AY llg++ ++ + FUN_002327-T1 434 EGNAYGNLGNAYYLLGDFRKAIE 456 678899999*******9998876 PP == domain 6 score: -2.5 bits; conditional E-value: 4.7 Vps54_N 198 ekYskvleAYkllgktqriad 218 + Y + +AY llg++ ++ + FUN_002327-T1 636 NAYGNLGNAYYLLGDFRKAIE 656 6899999********999877 PP == domain 7 score: 1.0 bits; conditional E-value: 0.41 Vps54_N 184 ldsqLsevckeFdsekYskvleAYkllgktqriad 218 l+ +++ +e + + Y + +AY+llg++ ++ + FUN_002327-T1 702 LEIAIEVGKREGEGNAYGNLGNAYQLLGDFRKAIE 736 5555555556667899*************999876 PP == domain 8 score: -2.4 bits; conditional E-value: 4.2 Vps54_N 196 dsekYskvleAYkllgktqriad 218 + + Y + +AY+ lg++ ++ + FUN_002327-T1 794 EGNAYGNLGNAYQSLGDFRKAIE 816 4688999**********998876 PP >> Transferase Transferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.1 0.0 0.014 11 273 324 .. 256 307 .. 247 347 .. 0.86 2 ? -2.8 0.0 3.6 2.7e+03 273 322 .. 416 465 .. 407 471 .. 0.82 3 ? -3.0 0.0 4 3e+03 273 323 .. 496 546 .. 486 551 .. 0.84 4 ? -1.7 0.0 1.6 1.2e+03 270 322 .. 613 665 .. 601 739 .. 0.76 5 ? -1.3 0.0 1.2 9.1e+02 275 332 .. 778 834 .. 771 843 .. 0.82 Alignments for each domain: == domain 1 score: 5.1 bits; conditional E-value: 0.014 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 e +e+ l ia+++ +r+ + +y GNa++s + +a e ++ l ++e FUN_002327-T1 256 EYHEKHLEIAIEVGNRVGEGSAYGYLGNAYQSLGDFRKAIEYHEKHLEIAIE 307 4556899********************************9999999987765 PP == domain 2 score: -2.8 bits; conditional E-value: 3.6 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsri 322 e +e+ l ia+++ +r+ + + GNa+ + +a e ++ l + FUN_002327-T1 416 EYHEKHLKIAIEVGHRVGEGNAYGNLGNAYYLLGDFRKAIEYHEKHLEIA 465 45568999*********************998888888888888777655 PP == domain 3 score: -3.0 bits; conditional E-value: 4 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 e +e+ l ia+++ +r+ + + GNa+ s + ++ e ++ l+ ++ FUN_002327-T1 496 EYHEKHLEIAIEVGNRVGEGGTYGNLGNAYRSLGEFRKGIEYHERHLKIAI 546 55668999***********************99999999999888888765 PP == domain 4 score: -1.7 bits; conditional E-value: 1.6 Transferase 270 kldeeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsri 322 k++e +e+ l ia+++ r+ + + GNa+ + +a e ++ l + FUN_002327-T1 613 KANEYHEKHLKIAIEVGDRVGEGNAYGNLGNAYYLLGDFRKAIEYHEKHLEIA 665 55666667777777777777777777777777776666666666666665544 PP == domain 5 score: -1.3 bits; conditional E-value: 1.2 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivekvkeavkk 332 +e+ l ia+++ +r + + GNa++s + +a e ++ l i+++v +v + FUN_002327-T1 778 HEKDLEIAIEVGNRFGEGNAYGNLGNAYQSLGDFRKAIEYHEKHLE-IAKEVGDRVGE 834 5578999999999***999******************999999985.56666666655 PP >> DUF386 YhcH/YjgK/YiaL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.1 0.38 2.8e+02 14 71 .. 87 144 .. 35 152 .. 0.64 2 ? 4.3 0.0 0.071 53 12 73 .. 245 306 .. 236 311 .. 0.87 3 ? 3.0 0.1 0.18 1.4e+02 18 73 .. 331 386 .. 320 428 .. 0.66 4 ? -0.2 0.0 1.8 1.3e+03 14 73 .. 447 506 .. 436 511 .. 0.76 5 ? 3.3 0.0 0.15 1.1e+02 14 79 .. 647 712 .. 637 724 .. 0.85 6 ? -0.2 0.0 1.8 1.3e+03 13 72 .. 726 785 .. 717 813 .. 0.79 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.38 DUF386 14 lppklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDi 71 l ++ka+e+ +++ ++e g +g+ + + y+ + + +E+H+k+++i FUN_002327-T1 87 LLGDVRKAIEYHEKHLEIAIEVGHRVGEGNAYRNLGNAYQLLGDVRKAIEYHEKHLEI 144 2245666666666666666666655555555555556666666666667777777666 PP == domain 2 score: 4.3 bits; conditional E-value: 0.071 DUF386 12 yelppklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiqi 73 ye + ++ka+e+ +++ ++e g+ +g ++ + y++ + + +E+H+k+++i i FUN_002327-T1 245 YESLSDFRKAIEYHEKHLEIAIEVGNRVGEGSAYGYLGNAYQSLGDFRKAIEYHEKHLEIAI 306 3323889**********99**************************************99966 PP == domain 3 score: 3.0 bits; conditional E-value: 0.18 DUF386 18 lkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiqi 73 l+ka+e+ +++ ++e g + +g+ + ++y++ + + +E+H+k+++i i FUN_002327-T1 331 LRKAIEYHEKHLKIAIEVGDRDGEGNGYGSFGNTYQSLGDFRKAIEYHEKHLEIAI 386 66677777666666777777777777766666777777777777777777766644 PP == domain 4 score: -0.2 bits; conditional E-value: 1.8 DUF386 14 lppklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiqi 73 l ++ka+e+ +++ ++e g +g + + y + + + +E+H+k+++i i FUN_002327-T1 447 LLGDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGSLGSAYRSLGDLRKAIEYHEKHLEIAI 506 446788888888888888888888888888777777888888888888999999988865 PP == domain 5 score: 3.3 bits; conditional E-value: 0.15 DUF386 14 lppklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiqivlegeE 79 l ++ka+e+ +++ ++e g +g + + y + ++ + +E+H+k+++i i + +E FUN_002327-T1 647 LLGDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGSFGSAYRSLGDSRKAIEYHEKHLEIAIEVGKRE 712 4478999999999999999999999999999999999999999999************99887776 PP == domain 6 score: -0.2 bits; conditional E-value: 1.8 DUF386 13 elppklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiq 72 +l ++ka+e+ +++ ++e g + +g+ + y++ + + +E+H+k ++i FUN_002327-T1 726 QLLGDFRKAIEYHEKQLEIAIEVGDRDGEGNAYGSLGRAYQSLGDFRKAIEYHEKDLEIA 785 334779999999988888999999999999988888889999999999999999977665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1328 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 578 (0.0226267); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 34 [number of targets reported over threshold] # CPU time: 0.59u 0.37s 00:00:00.96 Elapsed: 00:00:00.46 # Mc/sec: 11675.19 // Query: FUN_002328-T1 [L=240] Description: FUN_002328 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.3e-37 128.1 0.1 5.5e-37 127.7 0.1 1.1 1 Proteasome Proteasome subunit 9.4e-06 25.4 1.3 1.6e-05 24.7 1.3 1.4 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 127.7 0.1 4.3e-41 5.5e-37 14 189 .] 37 208 .. 35 208 .. 0.92 Alignments for each domain: == domain 1 score: 127.7 bits; conditional E-value: 4.3e-41 Proteasome 14 dgvvlaadkrata..gskllskdtveKifkiddhigvafaGlaaDartlvdyaraeaqlyrlrygepisvelvkrvaaklqaytqrsgrrpfgvsl 107 dgv+l+ad+rat+ ++++++++++Ki+ i ++i+++ aG+aaD++++++++++++ql++l++g++ ++ +a ++++ + ++++++ ++l FUN_002328-T1 37 DGVILGADTRATEigMDTIVADKNCSKIHYIAPNIYCCGAGTAADTEYVTQLISSNIQLHSLSTGRQARIV----TALCMLKQRLFRYQGYISAAL 128 9***********754457778888***********************************************....666666666666679999999 PP Proteasome 108 liagvdeegkprLyqidpsGsvieykdavaiGsgsqaaygvlekeykedltleeavelakkalkealerdklsgknievavi 189 +++ vd +g p L ++ p+Gs+ + ++v + +gs aa++v+e+++k+d++l+ea++l+++a+ + +d sg+ +++++i FUN_002328-T1 129 VLGAVDLNG-PTLHTVYPHGSTDKL-PYVTMSYGSLAAMSVFESRCKPDMELDEAKKLVRDAIAVGIFNDLGSGSDVDLCII 208 999999776.***************.8****************************************************997 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 1.3 1.3e-09 1.6e-05 1 18 [. 222 239 .. 222 240 .] 0.96 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 1.3e-09 Pr_beta_C 1 PNergeRqgsYkfkrGTT 18 +N +g Rqg+Y +krGTT FUN_002328-T1 222 ANDKGVRQGRYSYKRGTT 239 8***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (240 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 474 (0.0185555); expected 510.9 (0.02) Passed bias filter: 428 (0.0167547); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2456.40 // Query: FUN_002329-T1 [L=1605] Description: FUN_002329 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-226 732.4 96.4 4.5e-16 59.3 0.5 15.7 18 TPR_12 Tetratricopeptide repeat 1.6e-212 670.3 50.5 7.2e-07 29.3 0.0 29.3 29 TPR_7 Tetratricopeptide repeat 1.2e-178 572.9 157.7 3e-07 30.4 0.3 29.5 29 TPR_1 Tetratricopeptide repeat 1.1e-112 365.7 51.4 1.6e-06 28.4 0.0 29.0 29 TPR_10 Tetratricopeptide repeat 3.1e-103 329.7 128.2 7.2e-06 26.2 0.1 29.0 29 TPR_8 Tetratricopeptide repeat 2.3e-72 233.7 126.3 0.0047 17.4 0.1 28.9 28 TPR_2 Tetratricopeptide repeat 3.6e-49 168.2 0.0 5.4e-49 167.7 0.0 1.2 1 CHAT CHAT domain 1.1e-32 112.3 68.3 3.6 8.2 0.0 26.6 27 Rapsyn_N Rapsyn N-terminal myristoylation and linker 4.2e-31 105.1 66.9 11 7.1 0.0 27.6 27 TPR_17 Tetratricopeptide repeat 1.1e-30 103.4 64.3 5.4 8.5 0.0 28.2 29 TPR_14 Tetratricopeptide repeat 7.2e-26 91.7 8.7 0.0087 15.9 0.0 10.1 11 TPR_MalT MalT-like TPR region 7.5e-21 73.8 37.5 97 4.5 0.0 25.7 27 TPR_6 Tetratricopeptide repeat 3.2e-18 66.0 0.1 96 3.7 0.0 21.3 27 DUF2977 Protein of unknown function (DUF2977) 1.4e-16 60.3 0.4 70 3.7 0.0 18.5 21 DBD_Tnp_Mut MuDR family transposase 1.2e-14 53.8 9.7 2e+02 3.6 0.0 19.2 21 TPR_4 Tetratricopeptide repeat 6.2e-14 52.6 14.9 0.47 10.3 0.0 8.3 11 SNAP Soluble NSF attachment protein, SNAP 9.3e-14 52.0 52.7 1.4 9.9 0.1 17.8 19 TPR_16 Tetratricopeptide repeat 1.3e-13 50.6 57.2 32 5.5 0.0 25.9 29 PPR PPR repeat 5.2e-13 49.5 48.9 4.7 7.3 0.9 22.5 24 RPN7 26S proteasome subunit RPN7 2.3e-07 31.2 5.9 2.6e+02 2.3 0.0 15.5 24 TMP_C Tape measure protein C-terminal 3.6e-06 26.4 0.0 15 4.5 0.0 8.4 10 Transferase Transferase family 8.1e-06 26.0 36.0 1.1e+02 2.5 0.0 20.3 26 TPR_15 Tetratricopeptide repeat 0.0013 19.2 36.7 4.2e+02 1.6 0.0 18.9 22 FbpC_C_terminal FbpC C-terminal regulatory nucleotide bindin ------ inclusion threshold ------ 0.016 16.0 30.7 17 6.3 0.0 15.0 20 TPR_19 Tetratricopeptide repeat 0.028 15.2 30.7 13 6.5 0.0 12.4 14 DUF8155 Domain of unknown function (DUF8155) N-termi 0.81 10.1 53.2 35 4.8 0.0 18.1 23 CAMSAP_CC1 Spectrin-binding region of Ca2+-Calmodulin 0.96 9.8 2.3 85 3.4 0.0 5.3 5 HAT_Syf1_M Pre-mRNA-splicing factor SYF1 middle HAT rep 9.4 6.8 54.3 65 4.1 0.1 18.9 22 TPR_9 Tetratricopeptide repeat Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.4 0.3 2.2e-09 2e-06 21 75 .. 10 62 .. 8 64 .. 0.96 2 ! 58.6 0.2 8e-19 7.3e-16 4 75 .. 73 142 .. 70 144 .. 0.96 3 ! 52.1 0.3 8.7e-17 8e-14 4 75 .. 153 222 .. 150 224 .. 0.95 4 ! 54.1 0.4 2e-17 1.9e-14 4 77 .] 233 304 .. 230 304 .. 0.96 5 ! 53.1 0.1 4.1e-17 3.8e-14 4 75 .. 313 382 .. 310 384 .. 0.96 6 ! 59.3 0.5 4.9e-19 4.5e-16 4 75 .. 393 462 .. 390 464 .. 0.96 7 ! 48.4 0.4 1.2e-15 1.1e-12 4 75 .. 473 542 .. 470 544 .. 0.95 8 ! 55.7 0.5 6.4e-18 5.8e-15 4 75 .. 513 582 .. 511 584 .. 0.96 9 ! 49.9 0.2 4.1e-16 3.7e-13 5 75 .. 554 622 .. 550 624 .. 0.96 10 ! 52.5 0.5 6.6e-17 6.1e-14 3 75 .. 592 662 .. 590 664 .. 0.96 11 ! 56.8 0.4 3e-18 2.7e-15 4 75 .. 633 702 .. 630 704 .. 0.96 12 ! 56.2 0.3 4.7e-18 4.3e-15 5 75 .. 674 742 .. 670 744 .. 0.96 13 ! 52.6 0.5 6e-17 5.4e-14 5 75 .. 714 782 .. 710 784 .. 0.95 14 ! 55.4 0.2 8.2e-18 7.5e-15 4 75 .. 753 822 .. 750 824 .. 0.96 15 ! 55.3 0.3 8.6e-18 7.8e-15 4 75 .. 833 902 .. 830 904 .. 0.96 16 ! 58.2 0.3 1.1e-18 1e-15 4 75 .. 913 982 .. 910 984 .. 0.96 17 ! 57.9 0.4 1.3e-18 1.2e-15 4 75 .. 993 1062 .. 991 1064 .. 0.96 18 ! 50.6 0.0 2.5e-16 2.3e-13 4 74 .. 1073 1141 .. 1070 1144 .. 0.95 Alignments for each domain: == domain 1 score: 28.4 bits; conditional E-value: 2.2e-09 TPR_12 21 eAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +A+e++ek l + ++ +d+ ++ ++nL+ +++ lgd+++A+e++e+ leia FUN_002329-T1 10 KAIEYHEKHLKITMEV--GDRAGEEKGYQNLAYAFQSLGDFRKAIEYHEKHLEIA 62 8***************..99*********************************98 PP == domain 2 score: 58.6 bits; conditional E-value: 8e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a++ l+++++ lg++ +A+e++ek le+a ++ +d+ ++ +++ Lg +y+ lgd+++A+e++e+ leia FUN_002329-T1 73 NAYRSLGNAYQSLGDFRKAIEYHEKHLEIAIEV--GDRVGEGNVYGSLGNAYQSLGDFRKAIEYHEKHLEIA 142 78989****************************..9**********************************98 PP == domain 3 score: 52.1 bits; conditional E-value: 8.7e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ k le+a ++ +++ ++ +a+ Lg++y+ lgd+++A+e++e+ leia FUN_002329-T1 153 NAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKV--GHRVGEGRAYGSLGIAYRSLGDFRKAIEYHEKDLEIA 222 78989****************************..99*****************************988886 PP == domain 4 score: 54.1 bits; conditional E-value: 2e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+ +++ lg++ +A+e++ k le+a ++ ++ ++ a+ nLg++y+ lgd+++A+e++e++leia++ FUN_002329-T1 233 VAYGNLGVAYQSLGDFRKAIEYHAKHLEIAIKI--GHQVGEEGAYGNLGTAYRSLGDFRKAIEYHEKCLEIAKE 304 5899*****************************..8999********************************986 PP == domain 5 score: 53.1 bits; conditional E-value: 4.1e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A++++ek le+a ++ +d+ ++ +a+ Lg +y+ lg +++A+e++++ leia FUN_002329-T1 313 SAYGNLGNAYQSLGDFGKAIDYHEKHLEIAIEV--GDRVGEGNAYGSLGNAYQSLGVFRKAIEYHKKHLEIA 382 7999*****************************..9**********************************98 PP == domain 6 score: 59.3 bits; conditional E-value: 4.9e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ek le+a ++ +d+ ++ +a+ Lg +y+ lgd+++A++++e+ leia FUN_002329-T1 393 NAYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEV--GDRVGEGRAYGSLGNAYQSLGDFRKAIDYHEKHLEIA 462 78989****************************..9**********************************98 PP == domain 7 score: 48.4 bits; conditional E-value: 1.2e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l ++++ lg + +A+e+++k le+a ++ +++ ++ +a+ Lg +y++lgd+++A+e++e+ leia FUN_002329-T1 473 NAYGSLVNAYQSLGVFRKAIEYHKKHLEIAIEV--GHRVGEGNAYGSLGNAYQLLGDFRKAIEYHEKHLEIA 542 7888899**************************..99*********************************98 PP == domain 8 score: 55.7 bits; conditional E-value: 6.4e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ek le+a ++ +d+ ++ a+ Lg +y+ lgd+ +A++++e+ leia FUN_002329-T1 513 NAYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEV--GDRVGEGKAYGSLGNAYQSLGDFGKAIDYHEKHLEIA 582 68988****************************..9**********************************98 PP == domain 9 score: 49.9 bits; conditional E-value: 4.1e-16 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ l+++++ lg++ +A++++ek le+a ++ +d+ ++ +a+ Lg +y+ lg +++A+e++e+ leia FUN_002329-T1 554 AYGSLGNAYQSLGDFGKAIDYHEKHLEIAIEV--GDRVEEGNAYGSLGNAYQSLGVFRKAIEYHEKHLEIA 622 7888****************************..9**********************************98 PP == domain 10 score: 52.5 bits; conditional E-value: 6.6e-17 TPR_12 3 atalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg + +A+e++ek le+a ++ +++ ++ +a+ Lg +y++lgd+++A+e++e+ leia FUN_002329-T1 592 GNAYGSLGNAYQSLGVFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYQLLGDFRKAIEFHEKHLEIA 662 578989****************************..99*********************************98 PP == domain 11 score: 56.8 bits; conditional E-value: 3e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ek le+a ++ +d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia FUN_002329-T1 633 NAYGSLGNAYQLLGDFRKAIEFHEKHLEIAIEV--GDRVGEGKAYGSLGNAYRSLGDFRKAIEYHEKHLEIA 702 78989****************************..9**********************************98 PP == domain 12 score: 56.2 bits; conditional E-value: 4.7e-18 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ l++++r lg++ +A+e++ek le+a ++ +d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia FUN_002329-T1 674 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GDRVGEGKAYGSLGNAYQSLGDFRKAIEYHEKHLEIA 742 7888****************************..9**********************************98 PP == domain 13 score: 52.6 bits; conditional E-value: 6e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ l+++++ lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y lgd+++A+e++ + leia FUN_002329-T1 714 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYKSLGDFRKAIEYHAKHLEIA 782 7888****************************..99*********************************98 PP == domain 14 score: 55.4 bits; conditional E-value: 8.2e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l++++ lg++ +A+e++ k le+a ++ +++ ++ +a+ nLg++y+ lgd+++A+e++++ leia FUN_002329-T1 753 NAYGSLGNAYKSLGDFRKAIEYHAKHLEIAIKV--GHRVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIA 822 78989****************************..99*********************************98 PP == domain 15 score: 55.3 bits; conditional E-value: 8.6e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ k le+a ++ +++ ++ +a+ Lg++y+ lgd+++A+e++++ leia FUN_002329-T1 833 NAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKV--GHRVGEGRAYGHLGIAYQSLGDFRKAIEYHKKHLEIA 902 78989****************************..99*********************************98 PP == domain 16 score: 58.2 bits; conditional E-value: 1.1e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ k le+a ++ +++ ++ +a+ nLg++y+ lgd+++A+e++++ leia FUN_002329-T1 913 NAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKV--GHRVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIA 982 78989****************************..99*********************************98 PP == domain 17 score: 57.9 bits; conditional E-value: 1.3e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ k le+a ++ +++ ++ +a+ nLg++y+ lgd+++A+e++++ leia FUN_002329-T1 993 NAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKV--GHRVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIA 1062 68988****************************..99*********************************98 PP == domain 18 score: 50.6 bits; conditional E-value: 2.5e-16 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +a+ nl+ ++r lg++ +A+e++ek+le+a ++ +++ ++ +a++n+g +y+ lg++e Al+ + a+e FUN_002329-T1 1073 NAYGNLGTAYRSLGDFRKAIEYHEKSLEIAIEV--GHRAGEGIAHHNIGNAYFCLGQFENALDKFGSAVET 1141 799******************************..9999************************99999886 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.0 0.0077 7.1 15 36 .] 8 29 .. 7 29 .. 0.92 2 ! 21.4 0.1 2.6e-07 0.00024 3 35 .. 36 68 .. 35 69 .. 0.92 3 ! 27.0 0.0 4.2e-09 3.8e-06 1 35 [. 74 108 .. 74 109 .. 0.94 4 ! 25.0 0.0 1.8e-08 1.7e-05 3 35 .. 116 148 .. 114 149 .. 0.90 5 ! 24.2 0.0 3.4e-08 3.1e-05 1 35 [. 154 188 .. 154 189 .. 0.93 6 ! 22.3 0.0 1.4e-07 0.00013 1 29 [. 194 222 .. 194 226 .. 0.92 7 ! 22.5 0.0 1.2e-07 0.00011 1 30 [. 234 263 .. 234 269 .. 0.91 8 ! 28.6 0.0 1.4e-09 1.2e-06 1 35 [. 274 308 .. 274 309 .. 0.93 9 ! 27.3 0.0 3.4e-09 3.1e-06 1 35 [. 314 348 .. 314 349 .. 0.95 10 ! 21.5 0.0 2.5e-07 0.00023 1 35 [. 354 388 .. 354 389 .. 0.93 11 ! 26.3 0.0 7.5e-09 6.8e-06 1 35 [. 394 428 .. 394 429 .. 0.95 12 ! 27.4 0.0 3.1e-09 2.8e-06 1 35 [. 434 468 .. 434 469 .. 0.95 13 ! 17.5 0.0 4.7e-06 0.0043 1 35 [. 474 508 .. 474 509 .. 0.92 14 ! 26.3 0.0 7.5e-09 6.8e-06 1 35 [. 514 548 .. 514 549 .. 0.95 15 ! 25.6 0.0 1.2e-08 1.1e-05 1 35 [. 554 588 .. 554 589 .. 0.95 16 ! 22.7 0.0 1e-07 9.2e-05 1 35 [. 594 628 .. 594 629 .. 0.93 17 ! 24.9 0.0 2.1e-08 1.9e-05 1 35 [. 634 668 .. 634 669 .. 0.95 18 ! 29.3 0.0 7.9e-10 7.2e-07 1 35 [. 674 708 .. 674 709 .. 0.95 19 ! 26.9 0.0 4.6e-09 4.2e-06 1 35 [. 714 748 .. 714 749 .. 0.93 20 ! 23.5 0.0 5.9e-08 5.4e-05 1 35 [. 754 788 .. 754 789 .. 0.93 21 ! 24.8 0.0 2.1e-08 1.9e-05 1 35 [. 794 828 .. 794 829 .. 0.93 22 ! 24.2 0.0 3.4e-08 3.1e-05 1 35 [. 834 868 .. 834 869 .. 0.93 23 ! 23.0 0.0 8.4e-08 7.6e-05 1 35 [. 874 908 .. 874 909 .. 0.93 24 ! 24.2 0.0 3.4e-08 3.1e-05 1 35 [. 914 948 .. 914 949 .. 0.93 25 ! 25.3 0.0 1.6e-08 1.4e-05 1 35 [. 954 988 .. 954 989 .. 0.94 26 ! 24.2 0.0 3.4e-08 3.1e-05 1 35 [. 994 1028 .. 994 1029 .. 0.93 27 ! 23.1 0.0 7.6e-08 6.9e-05 1 29 [. 1034 1062 .. 1034 1066 .. 0.94 28 ! 25.7 0.0 1.1e-08 1e-05 1 35 [. 1074 1108 .. 1074 1109 .. 0.94 29 ? 5.6 0.0 0.032 29 1 23 [. 1114 1136 .. 1114 1141 .. 0.89 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.0077 TPR_7 15 ydeAirlyerlLalakdpedre 36 +++Ai+++e++L ++++ +dr+ FUN_002329-T1 8 FRKAIEYHEKHLKITMEVGDRA 29 689****************995 PP == domain 2 score: 21.4 bits; conditional E-value: 2.6e-07 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La ++++lGd+++Ai+++e++L++a + ++r FUN_002329-T1 36 QNLAYAFQSLGDFRKAIEYHEKHLEIAIEAGHR 68 69************************9887776 PP == domain 3 score: 27.0 bits; conditional E-value: 4.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+++y++lGd+++Ai+++e++L++a + +dr FUN_002329-T1 74 AYRSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGDR 108 6789*************************999997 PP == domain 4 score: 25.0 bits; conditional E-value: 1.8e-08 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 ++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002329-T1 116 GSLGNAYQSLGDFRKAIEYHEKHLEIAIEVSHR 148 78************************9877765 PP == domain 5 score: 24.2 bits; conditional E-value: 3.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L++a + ++r FUN_002329-T1 154 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHR 188 7899************************9888876 PP == domain 6 score: 22.3 bits; conditional E-value: 1.4e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLala 29 a+++L+ +yr+lGd+++Ai+++e+ L++a FUN_002329-T1 194 AYGSLGIAYRSLGDFRKAIEYHEKDLEIA 222 7899********************99987 PP == domain 7 score: 22.5 bits; conditional E-value: 1.2e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalak 30 a+++L+ +y++lGd+++Ai+++ ++L++a FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEYHAKHLEIAI 263 789************************985 PP == domain 8 score: 28.6 bits; conditional E-value: 1.4e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +yr+lGd+++Ai+++e++L++ak+ + r FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIEYHEKCLEIAKEVSGR 308 789**************************998765 PP == domain 9 score: 27.3 bits; conditional E-value: 3.4e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+ +Ai+++e++L++a + +dr FUN_002329-T1 314 AYGNLGNAYQSLGDFGKAIDYHEKHLEIAIEVGDR 348 789**************************999997 PP == domain 10 score: 21.5 bits; conditional E-value: 2.5e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lG +++Ai++++++L++a + ++r FUN_002329-T1 354 AYGSLGNAYQSLGVFRKAIEYHKKHLEIAIEVGHR 388 7899************************9988876 PP == domain 11 score: 26.3 bits; conditional E-value: 7.5e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd+++Ai+++e++L++a + +dr FUN_002329-T1 394 AYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGDR 428 7899*************************999997 PP == domain 12 score: 27.4 bits; conditional E-value: 3.1e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + +dr FUN_002329-T1 434 AYGSLGNAYQSLGDFRKAIDYHEKHLEIAIEVGDR 468 7899*************************999997 PP == domain 13 score: 17.5 bits; conditional E-value: 4.7e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L ++y++lG +++Ai++++++L++a + ++r FUN_002329-T1 474 AYGSLVNAYQSLGVFRKAIEYHKKHLEIAIEVGHR 508 67899***********************9988876 PP == domain 14 score: 26.3 bits; conditional E-value: 7.5e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd+++Ai+++e++L++a + +dr FUN_002329-T1 514 AYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGDR 548 7899*************************999997 PP == domain 15 score: 25.6 bits; conditional E-value: 1.2e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+ +Ai+++e++L++a + +dr FUN_002329-T1 554 AYGSLGNAYQSLGDFGKAIDYHEKHLEIAIEVGDR 588 7899*************************999997 PP == domain 16 score: 22.7 bits; conditional E-value: 1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lG +++Ai+++e++L++a + ++r FUN_002329-T1 594 AYGSLGNAYQSLGVFRKAIEYHEKHLEIAIEVGHR 628 7899************************9988876 PP == domain 17 score: 24.9 bits; conditional E-value: 2.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd+++Ai+++e++L++a + +dr FUN_002329-T1 634 AYGSLGNAYQLLGDFRKAIEFHEKHLEIAIEVGDR 668 7899*************************999997 PP == domain 18 score: 29.3 bits; conditional E-value: 7.9e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + +dr FUN_002329-T1 674 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAIEVGDR 708 7899*************************999997 PP == domain 19 score: 26.9 bits; conditional E-value: 4.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002329-T1 714 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHR 748 7899************************9988876 PP == domain 20 score: 23.5 bits; conditional E-value: 5.9e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++ ++L++a + ++r FUN_002329-T1 754 AYGSLGNAYKSLGDFRKAIEYHAKHLEIAIKVGHR 788 7899************************9888876 PP == domain 21 score: 24.8 bits; conditional E-value: 2.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai++++++L++a + ++r FUN_002329-T1 794 AYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEAGHR 828 789*************************9887776 PP == domain 22 score: 24.2 bits; conditional E-value: 3.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L++a + ++r FUN_002329-T1 834 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHR 868 7899************************9888876 PP == domain 23 score: 23.0 bits; conditional E-value: 8.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++ L+ +y++lGd+++Ai++++++L++a + ++r FUN_002329-T1 874 AYGHLGIAYQSLGDFRKAIEYHKKHLEIAIEVGHR 908 6789************************9988876 PP == domain 24 score: 24.2 bits; conditional E-value: 3.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L++a + ++r FUN_002329-T1 914 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHR 948 7899************************9888876 PP == domain 25 score: 25.3 bits; conditional E-value: 1.6e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai++++++L++a + ++r FUN_002329-T1 954 AYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEVGHR 988 789*************************9988876 PP == domain 26 score: 24.2 bits; conditional E-value: 3.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L++a + ++r FUN_002329-T1 994 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHR 1028 7899************************9888876 PP == domain 27 score: 23.1 bits; conditional E-value: 7.6e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLala 29 a+++L+ +y++lGd+++Ai++++++L++a FUN_002329-T1 1034 AYGNLGIAYQSLGDFRKAIEYHKKHLEIA 1062 789***********************997 PP == domain 28 score: 25.7 bits; conditional E-value: 1.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +yr+lGd+++Ai+++e+ L++a + ++r FUN_002329-T1 1074 AYGNLGTAYRSLGDFRKAIEYHEKSLEIAIEVGHR 1108 789*************************9999887 PP == domain 29 score: 5.6 bits; conditional E-value: 0.032 TPR_7 1 aLsaLariyrklGdydeAirlye 23 a+++++++y lG++++A++ + FUN_002329-T1 1114 AHHNIGNAYFCLGQFENALDKFG 1136 79*****************9885 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.2 0.8 7.3e+02 17 30 .. 8 21 .. 7 21 .. 0.80 2 ! 21.0 0.9 3.1e-07 0.00028 2 30 .. 33 61 .. 32 62 .. 0.94 3 ! 25.9 0.3 9e-09 8.2e-06 2 30 .. 73 101 .. 72 102 .. 0.95 4 ! 25.8 0.1 9.6e-09 8.8e-06 3 30 .. 114 141 .. 112 142 .. 0.94 5 ! 23.0 0.4 7.3e-08 6.6e-05 2 30 .. 153 181 .. 152 182 .. 0.94 6 ! 20.4 0.1 4.9e-07 0.00045 2 26 .. 193 217 .. 192 222 .. 0.93 7 ! 24.8 0.2 2e-08 1.8e-05 3 30 .. 234 261 .. 232 262 .. 0.94 8 ! 30.4 0.3 3.3e-10 3e-07 3 31 .. 274 302 .. 273 304 .. 0.95 9 ! 28.2 0.2 1.8e-09 1.6e-06 3 30 .. 314 341 .. 312 342 .. 0.95 10 ! 17.7 0.2 3.5e-06 0.0032 2 30 .. 353 381 .. 352 382 .. 0.95 11 ! 26.1 0.6 7.6e-09 7e-06 2 30 .. 393 421 .. 392 422 .. 0.95 12 ! 26.8 0.2 4.8e-09 4.4e-06 2 30 .. 433 461 .. 432 462 .. 0.95 13 ! 7.3 0.1 0.007 6.4 9 30 .. 480 501 .. 473 502 .. 0.92 14 ! 26.1 0.6 7.6e-09 7e-06 2 30 .. 513 541 .. 512 542 .. 0.95 15 ! 25.8 0.2 1e-08 9.1e-06 2 30 .. 553 581 .. 552 582 .. 0.96 16 ! 18.0 0.2 2.8e-06 0.0026 2 30 .. 593 621 .. 592 622 .. 0.95 17 ! 24.4 0.2 2.6e-08 2.4e-05 2 30 .. 633 661 .. 632 662 .. 0.95 18 ! 27.8 0.2 2.2e-09 2e-06 2 30 .. 673 701 .. 672 702 .. 0.96 19 ! 27.7 0.3 2.4e-09 2.1e-06 2 30 .. 713 741 .. 712 742 .. 0.96 20 ! 22.6 0.4 1e-07 9.3e-05 2 30 .. 753 781 .. 752 782 .. 0.94 21 ! 28.4 0.4 1.5e-09 1.4e-06 2 30 .. 793 821 .. 792 822 .. 0.96 22 ! 23.0 0.4 7.3e-08 6.6e-05 2 30 .. 833 861 .. 832 862 .. 0.94 23 ! 25.2 0.3 1.5e-08 1.4e-05 2 30 .. 873 901 .. 872 902 .. 0.95 24 ! 23.0 0.4 7.3e-08 6.6e-05 2 30 .. 913 941 .. 912 942 .. 0.94 25 ! 28.4 0.4 1.5e-09 1.4e-06 2 30 .. 953 981 .. 952 982 .. 0.96 26 ! 23.0 0.4 7.3e-08 6.6e-05 2 30 .. 993 1021 .. 992 1022 .. 0.94 27 ! 28.4 0.4 1.5e-09 1.4e-06 2 30 .. 1033 1061 .. 1032 1062 .. 0.96 28 ! 29.7 0.1 5.8e-10 5.3e-07 2 30 .. 1073 1101 .. 1072 1102 .. 0.96 29 ! 16.7 0.0 7.4e-06 0.0068 3 27 .. 1114 1138 .. 1112 1141 .. 0.87 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 0.8 TPR_1 17 ydeAleyyekALel 30 + +A+ey ek L++ FUN_002329-T1 8 FRKAIEYHEKHLKI 21 56899999998886 PP == domain 2 score: 21.0 bits; conditional E-value: 3.1e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k + nl++a+++lg++ +A+ey ek Le+ FUN_002329-T1 33 KGYQNLAYAFQSLGDFRKAIEYHEKHLEI 61 5799***********************98 PP == domain 3 score: 25.9 bits; conditional E-value: 9e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002329-T1 73 NAYRSLGNAYQSLGDFRKAIEYHEKHLEI 101 5999***********************98 PP == domain 4 score: 25.8 bits; conditional E-value: 9.6e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 ++ lGnay++lg++ +A+ey ek Le+ FUN_002329-T1 114 VYGSLGNAYQSLGDFRKAIEYHEKHLEI 141 7999**********************98 PP == domain 5 score: 23.0 bits; conditional E-value: 7.3e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey k Le+ FUN_002329-T1 153 NAYGSLGNAYQSLGDFRKAIEYHAKHLEI 181 59********************9999998 PP == domain 6 score: 20.4 bits; conditional E-value: 4.9e-07 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ lG ay++lg++ +A+ey ek FUN_002329-T1 193 RAYGSLGIAYRSLGDFRKAIEYHEK 217 69********************998 PP == domain 7 score: 24.8 bits; conditional E-value: 2e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlG+ay++lg++ +A+ey k Le+ FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEYHAKHLEI 261 9********************9999998 PP == domain 8 score: 30.4 bits; conditional E-value: 3.3e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlG ay++lg++ +A+ey ek+Le+ FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIEYHEKCLEIA 302 8**************************96 PP == domain 9 score: 28.2 bits; conditional E-value: 1.8e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A++y ek Le+ FUN_002329-T1 314 AYGNLGNAYQSLGDFGKAIDYHEKHLEI 341 9*************************98 PP == domain 10 score: 17.7 bits; conditional E-value: 3.5e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg + +A+ey +k Le+ FUN_002329-T1 353 NAYGSLGNAYQSLGVFRKAIEYHKKHLEI 381 59*************************98 PP == domain 11 score: 26.1 bits; conditional E-value: 7.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay+ lg++ +A+ey ek Le+ FUN_002329-T1 393 NAYGSLGNAYQLLGDFRKAIEYHEKHLEI 421 59*************************98 PP == domain 12 score: 26.8 bits; conditional E-value: 4.8e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A++y ek Le+ FUN_002329-T1 433 RAYGSLGNAYQSLGDFRKAIDYHEKHLEI 461 69*************************98 PP == domain 13 score: 7.3 bits; conditional E-value: 0.007 TPR_1 9 nayfklgkydeAleyyekALel 30 nay++lg + +A+ey +k Le+ FUN_002329-T1 480 NAYQSLGVFRKAIEYHKKHLEI 501 89******************98 PP == domain 14 score: 26.1 bits; conditional E-value: 7.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay+ lg++ +A+ey ek Le+ FUN_002329-T1 513 NAYGSLGNAYQLLGDFRKAIEYHEKHLEI 541 59*************************98 PP == domain 15 score: 25.8 bits; conditional E-value: 1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ lGnay++lg++ +A++y ek Le+ FUN_002329-T1 553 KAYGSLGNAYQSLGDFGKAIDYHEKHLEI 581 79*************************98 PP == domain 16 score: 18.0 bits; conditional E-value: 2.8e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg + +A+ey ek Le+ FUN_002329-T1 593 NAYGSLGNAYQSLGVFRKAIEYHEKHLEI 621 59*************************98 PP == domain 17 score: 24.4 bits; conditional E-value: 2.6e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay+ lg++ +A+e+ ek Le+ FUN_002329-T1 633 NAYGSLGNAYQLLGDFRKAIEFHEKHLEI 661 59*************************98 PP == domain 18 score: 27.8 bits; conditional E-value: 2.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ lGnay++lg++ +A+ey ek Le+ FUN_002329-T1 673 KAYGSLGNAYRSLGDFRKAIEYHEKHLEI 701 79*************************98 PP == domain 19 score: 27.7 bits; conditional E-value: 2.4e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ lGnay++lg++ +A+ey ek Le+ FUN_002329-T1 713 KAYGSLGNAYQSLGDFRKAIEYHEKHLEI 741 79*************************98 PP == domain 20 score: 22.6 bits; conditional E-value: 1e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay +lg++ +A+ey k Le+ FUN_002329-T1 753 NAYGSLGNAYKSLGDFRKAIEYHAKHLEI 781 59********************9999998 PP == domain 21 score: 28.4 bits; conditional E-value: 1.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay++lg++ +A+ey +k Le+ FUN_002329-T1 793 RAYGNLGIAYQSLGDFRKAIEYHKKHLEI 821 79*************************98 PP == domain 22 score: 23.0 bits; conditional E-value: 7.3e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey k Le+ FUN_002329-T1 833 NAYGSLGNAYQSLGDFRKAIEYHAKHLEI 861 59********************9999998 PP == domain 23 score: 25.2 bits; conditional E-value: 1.5e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lG ay++lg++ +A+ey +k Le+ FUN_002329-T1 873 RAYGHLGIAYQSLGDFRKAIEYHKKHLEI 901 69*************************98 PP == domain 24 score: 23.0 bits; conditional E-value: 7.3e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey k Le+ FUN_002329-T1 913 NAYGSLGNAYQSLGDFRKAIEYHAKHLEI 941 59********************9999998 PP == domain 25 score: 28.4 bits; conditional E-value: 1.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay++lg++ +A+ey +k Le+ FUN_002329-T1 953 RAYGNLGIAYQSLGDFRKAIEYHKKHLEI 981 79*************************98 PP == domain 26 score: 23.0 bits; conditional E-value: 7.3e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey k Le+ FUN_002329-T1 993 NAYGSLGNAYQSLGDFRKAIEYHAKHLEI 1021 59********************9999998 PP == domain 27 score: 28.4 bits; conditional E-value: 1.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay++lg++ +A+ey +k Le+ FUN_002329-T1 1033 RAYGNLGIAYQSLGDFRKAIEYHKKHLEI 1061 79*************************98 PP == domain 28 score: 29.7 bits; conditional E-value: 5.8e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay++lg++ +A+ey ek Le+ FUN_002329-T1 1073 NAYGNLGTAYRSLGDFRKAIEYHEKSLEI 1101 69**************************8 PP == domain 29 score: 16.7 bits; conditional E-value: 7.4e-06 TPR_1 3 alynlGnayfklgkydeAleyyekA 27 a+ n+Gnayf lg+++ Al+ + A FUN_002329-T1 1114 AHHNIGNAYFCLGQFENALDKFGSA 1138 899****************976655 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.1 3.5 3.1e+03 23 36 .. 6 19 .. 5 21 .. 0.88 2 ! 8.9 0.2 0.0023 2.1 5 33 .. 35 63 .. 35 65 .. 0.90 3 ! 14.0 0.1 5.7e-05 0.052 4 34 .. 74 104 .. 72 105 .. 0.88 4 ! 13.5 0.0 8.4e-05 0.077 5 35 .. 115 145 .. 113 146 .. 0.91 5 ! 12.2 0.0 0.00022 0.2 4 34 .. 154 184 .. 152 185 .. 0.90 6 ! 16.0 0.0 1.4e-05 0.013 4 35 .. 194 225 .. 192 225 .. 0.93 7 ! 13.7 0.0 7.6e-05 0.069 4 33 .. 234 263 .. 233 265 .. 0.89 8 ! 28.4 0.0 1.7e-09 1.6e-06 4 38 .. 274 308 .. 273 309 .. 0.96 9 ! 16.6 0.0 9e-06 0.0082 3 34 .. 313 344 .. 312 345 .. 0.92 10 ! 9.4 0.0 0.0017 1.5 4 34 .. 354 384 .. 352 385 .. 0.88 11 ! 12.6 0.0 0.00016 0.15 4 35 .. 394 425 .. 392 425 .. 0.91 12 ! 13.7 0.0 7.1e-05 0.065 4 34 .. 434 464 .. 432 465 .. 0.91 13 ? 6.5 0.0 0.013 12 4 34 .. 474 504 .. 472 505 .. 0.90 14 ! 12.6 0.0 0.00016 0.15 4 35 .. 514 545 .. 512 545 .. 0.91 15 ! 12.0 0.0 0.00024 0.22 4 34 .. 554 584 .. 553 585 .. 0.91 16 ! 10.6 0.0 0.0007 0.64 4 34 .. 594 624 .. 592 625 .. 0.90 17 ! 11.2 0.0 0.00047 0.42 4 34 .. 634 664 .. 632 665 .. 0.91 18 ! 14.1 0.0 5.3e-05 0.048 4 35 .. 674 705 .. 673 705 .. 0.91 19 ! 14.0 0.0 5.9e-05 0.054 4 35 .. 714 745 .. 713 745 .. 0.91 20 ! 10.5 0.0 0.00077 0.7 4 34 .. 754 784 .. 752 785 .. 0.90 21 ! 14.7 0.0 3.7e-05 0.034 4 33 .. 794 823 .. 792 825 .. 0.90 22 ! 12.2 0.0 0.00022 0.2 4 34 .. 834 864 .. 832 865 .. 0.90 23 ! 12.4 0.0 0.00019 0.17 4 34 .. 874 904 .. 872 905 .. 0.91 24 ! 12.2 0.0 0.00022 0.2 4 34 .. 914 944 .. 912 945 .. 0.90 25 ! 15.1 0.0 2.6e-05 0.024 4 34 .. 954 984 .. 952 985 .. 0.91 26 ! 12.2 0.0 0.00022 0.2 4 34 .. 994 1024 .. 992 1025 .. 0.90 27 ! 15.1 0.0 2.6e-05 0.024 4 34 .. 1034 1064 .. 1032 1065 .. 0.91 28 ! 22.1 0.0 1.7e-07 0.00015 4 35 .. 1074 1105 .. 1072 1105 .. 0.94 29 ? 6.4 0.0 0.014 13 6 23 .. 1116 1133 .. 1116 1141 .. 0.90 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 3.5 TPR_10 23 elleealairervl 36 ++++a++ +e++l FUN_002329-T1 6 VYFRKAIEYHEKHL 19 69*********998 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0023 TPR_10 5 lnnLanalraqgryeeAeelleealaire 33 + nLa a +++g++ A e++e+ l+i+ FUN_002329-T1 35 YQNLAYAFQSLGDFRKAIEYHEKHLEIAI 63 67********************9988876 PP == domain 3 score: 14.0 bits; conditional E-value: 5.7e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++e+ l+i+ + FUN_002329-T1 74 AYRSLGNAYQSLGDFRKAIEYHEKHLEIAIE 104 7889*******************99998776 PP == domain 4 score: 13.5 bits; conditional E-value: 8.4e-05 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + L+na++++g++ A e++e+ l+i+ +v FUN_002329-T1 115 YGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 145 789********************99998776 PP == domain 5 score: 12.2 bits; conditional E-value: 0.00022 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++ + l+i+ + FUN_002329-T1 154 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIK 184 7999******************998888776 PP == domain 6 score: 16.0 bits; conditional E-value: 1.4e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+ a+r++g++ A e++e+ l+i+ +v FUN_002329-T1 194 AYGSLGIAYRSLGDFRKAIEYHEKDLEIAIEV 225 8999***********************98776 PP == domain 7 score: 13.7 bits; conditional E-value: 7.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealaire 33 ++ nL++a++++g++ A e++ + l+i+ FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEYHAKHLEIAI 263 799*******************99888765 PP == domain 8 score: 28.4 bits; conditional E-value: 1.7e-09 TPR_10 4 slnnLanalraqgryeeAeelleealairervlGp 38 ++ nL++a+r++g++ A e++e++l+i+++v G+ FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIEYHEKCLEIAKEVSGR 308 799*****************************996 PP == domain 9 score: 16.6 bits; conditional E-value: 9e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+na++++g++ A +++e+ l+i+ + FUN_002329-T1 313 SAYGNLGNAYQSLGDFGKAIDYHEKHLEIAIE 344 79***********************9999876 PP == domain 10 score: 9.4 bits; conditional E-value: 0.0017 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g + A e++++ l+i+ + FUN_002329-T1 354 AYGSLGNAYQSLGVFRKAIEYHKKHLEIAIE 384 7999******************999988766 PP == domain 11 score: 12.6 bits; conditional E-value: 0.00016 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++ +g++ A e++e+ l+i+ +v FUN_002329-T1 394 AYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEV 425 7999********************99998765 PP == domain 12 score: 13.7 bits; conditional E-value: 7.1e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A +++e+ l+i+ + FUN_002329-T1 434 AYGSLGNAYQSLGDFRKAIDYHEKHLEIAIE 464 8999********************9999876 PP == domain 13 score: 6.5 bits; conditional E-value: 0.013 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L na++++g + A e++++ l+i+ + FUN_002329-T1 474 AYGSLVNAYQSLGVFRKAIEYHKKHLEIAIE 504 7999*******************99998876 PP == domain 14 score: 12.6 bits; conditional E-value: 0.00016 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++ +g++ A e++e+ l+i+ +v FUN_002329-T1 514 AYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEV 545 7999********************99998765 PP == domain 15 score: 12.0 bits; conditional E-value: 0.00024 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A +++e+ l+i+ + FUN_002329-T1 554 AYGSLGNAYQSLGDFGKAIDYHEKHLEIAIE 584 7899********************9999876 PP == domain 16 score: 10.6 bits; conditional E-value: 0.0007 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g + A e++e+ l+i+ + FUN_002329-T1 594 AYGSLGNAYQSLGVFRKAIEYHEKHLEIAIE 624 7999*******************99998876 PP == domain 17 score: 11.2 bits; conditional E-value: 0.00047 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++ +g++ A e++e+ l+i+ + FUN_002329-T1 634 AYGSLGNAYQLLGDFRKAIEFHEKHLEIAIE 664 7999********************9999876 PP == domain 18 score: 14.1 bits; conditional E-value: 5.3e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+r++g++ A e++e+ l+i+ +v FUN_002329-T1 674 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAIEV 705 7899********************99998765 PP == domain 19 score: 14.0 bits; conditional E-value: 5.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+ +v FUN_002329-T1 714 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 745 7899********************99998765 PP == domain 20 score: 10.5 bits; conditional E-value: 0.00077 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+ ++g++ A e++ + l+i+ + FUN_002329-T1 754 AYGSLGNAYKSLGDFRKAIEYHAKHLEIAIK 784 7999******************998888776 PP == domain 21 score: 14.7 bits; conditional E-value: 3.7e-05 TPR_10 4 slnnLanalraqgryeeAeelleealaire 33 ++ nL+ a++++g++ A e++++ l+i+ FUN_002329-T1 794 AYGNLGIAYQSLGDFRKAIEYHKKHLEIAI 823 89*********************9888875 PP == domain 22 score: 12.2 bits; conditional E-value: 0.00022 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++ + l+i+ + FUN_002329-T1 834 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIK 864 7999******************998888776 PP == domain 23 score: 12.4 bits; conditional E-value: 0.00019 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ +L+ a++++g++ A e++++ l+i+ + FUN_002329-T1 874 AYGHLGIAYQSLGDFRKAIEYHKKHLEIAIE 904 899********************99998876 PP == domain 24 score: 12.2 bits; conditional E-value: 0.00022 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++ + l+i+ + FUN_002329-T1 914 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIK 944 7999******************998888776 PP == domain 25 score: 15.1 bits; conditional E-value: 2.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+ a++++g++ A e++++ l+i+ + FUN_002329-T1 954 AYGNLGIAYQSLGDFRKAIEYHKKHLEIAIE 984 89*********************99998876 PP == domain 26 score: 12.2 bits; conditional E-value: 0.00022 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++ + l+i+ + FUN_002329-T1 994 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIK 1024 7999******************998888776 PP == domain 27 score: 15.1 bits; conditional E-value: 2.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+ a++++g++ A e++++ l+i+ + FUN_002329-T1 1034 AYGNLGIAYQSLGDFRKAIEYHKKHLEIAIE 1064 89*********************99998876 PP == domain 28 score: 22.1 bits; conditional E-value: 1.7e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL++a+r++g++ A e++e++l+i+ +v FUN_002329-T1 1074 AYGNLGTAYRSLGDFRKAIEYHEKSLEIAIEV 1105 89**************************9876 PP == domain 29 score: 6.4 bits; conditional E-value: 0.014 TPR_10 6 nnLanalraqgryeeAee 23 +n++na++ +g++e A++ FUN_002329-T1 1116 HNIGNAYFCLGQFENALD 1133 8*************9985 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 9 8.2e+03 23 30 .. 7 14 .. 5 18 .. 0.74 2 ! 13.7 0.4 8.4e-05 0.077 3 30 .. 34 61 .. 32 62 .. 0.89 3 ! 13.1 0.2 0.00013 0.12 6 30 .. 77 101 .. 73 102 .. 0.86 4 ! 16.0 0.1 1.5e-05 0.014 3 30 .. 114 141 .. 112 142 .. 0.90 5 ! 14.5 0.2 4.5e-05 0.041 3 23 .. 154 174 .. 152 182 .. 0.88 6 ! 13.8 0.1 7.5e-05 0.069 2 26 .. 193 217 .. 192 222 .. 0.89 7 ! 15.1 0.1 3.1e-05 0.028 3 23 .. 234 254 .. 233 262 .. 0.90 8 ! 26.2 0.1 7.9e-09 7.2e-06 3 32 .. 274 303 .. 272 305 .. 0.95 9 ! 17.2 0.1 6.2e-06 0.0057 2 30 .. 313 341 .. 312 342 .. 0.90 10 ! 8.9 0.1 0.003 2.7 3 30 .. 354 381 .. 352 382 .. 0.87 11 ! 14.4 0.2 4.9e-05 0.044 3 30 .. 394 421 .. 392 422 .. 0.90 12 ! 15.7 0.1 2e-05 0.018 2 30 .. 433 461 .. 432 462 .. 0.90 13 ? 4.5 0.1 0.073 66 3 30 .. 474 501 .. 472 502 .. 0.87 14 ! 14.4 0.2 4.9e-05 0.044 3 30 .. 514 541 .. 512 542 .. 0.90 15 ! 15.0 0.2 3.2e-05 0.029 2 30 .. 553 581 .. 552 582 .. 0.90 16 ! 9.6 0.1 0.0017 1.5 3 30 .. 594 621 .. 592 622 .. 0.89 17 ! 12.9 0.1 0.00015 0.14 3 30 .. 634 661 .. 632 662 .. 0.89 18 ! 17.3 0.2 5.7e-06 0.0052 2 30 .. 673 701 .. 672 702 .. 0.90 19 ! 17.2 0.2 6.2e-06 0.0057 2 30 .. 713 741 .. 712 742 .. 0.90 20 ! 15.2 0.2 2.8e-05 0.026 3 23 .. 754 774 .. 752 782 .. 0.89 21 ! 16.6 0.2 9.8e-06 0.009 2 30 .. 793 821 .. 792 822 .. 0.89 22 ! 14.5 0.2 4.5e-05 0.041 3 23 .. 834 854 .. 832 862 .. 0.88 23 ! 14.9 0.1 3.4e-05 0.031 2 30 .. 873 901 .. 872 902 .. 0.89 24 ! 14.5 0.2 4.5e-05 0.041 3 23 .. 914 934 .. 912 942 .. 0.88 25 ! 16.6 0.2 9.8e-06 0.009 2 30 .. 953 981 .. 952 982 .. 0.89 26 ! 14.5 0.2 4.5e-05 0.041 3 23 .. 994 1014 .. 992 1022 .. 0.88 27 ! 16.6 0.2 9.8e-06 0.009 2 30 .. 1033 1061 .. 1032 1062 .. 0.89 28 ! 22.0 0.1 1.8e-07 0.00017 3 31 .. 1074 1102 .. 1072 1102 .. 0.95 29 ? 5.3 0.0 0.043 39 3 21 .. 1114 1132 .. 1113 1140 .. 0.91 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 9 TPR_8 23 yyekalel 30 y++ka+e+ FUN_002329-T1 7 YFRKAIEY 14 88999886 PP == domain 2 score: 13.7 bits; conditional E-value: 8.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 y+nl+++ ++lgd+ +A+ey ek le+ FUN_002329-T1 34 GYQNLAYAFQSLGDFRKAIEYHEKHLEI 61 69*******************9987776 PP == domain 3 score: 13.1 bits; conditional E-value: 0.00013 TPR_8 6 nlGliylklgdyeeAkeyyekalel 30 lG++y++lgd+ +A+ey ek le+ FUN_002329-T1 77 SLGNAYQSLGDFRKAIEYHEKHLEI 101 69****************9987776 PP == domain 4 score: 16.0 bits; conditional E-value: 1.5e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 +y lG++y++lgd+ +A+ey ek le+ FUN_002329-T1 114 VYGSLGNAYQSLGDFRKAIEYHEKHLEI 141 7999*****************9987776 PP == domain 5 score: 14.5 bits; conditional E-value: 4.5e-05 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay lG++y++lgd+ +A+ey FUN_002329-T1 154 AYGSLGNAYQSLGDFRKAIEY 174 89******************9 PP == domain 6 score: 13.8 bits; conditional E-value: 7.5e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay lG +y++lgd+ +A+ey ek FUN_002329-T1 193 RAYGSLGIAYRSLGDFRKAIEYHEK 217 79********************777 PP == domain 7 score: 15.1 bits; conditional E-value: 3.1e-05 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay nlG +y++lgd+ +A+ey FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEY 254 79******************9 PP == domain 8 score: 26.2 bits; conditional E-value: 7.9e-09 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG +y++lgd+ +A+ey ek+le+++ FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIEYHEKCLEIAK 303 8***************************86 PP == domain 9 score: 17.2 bits; conditional E-value: 6.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd+ +A+ y ek le+ FUN_002329-T1 313 SAYGNLGNAYQSLGDFGKAIDYHEKHLEI 341 59********************8887776 PP == domain 10 score: 8.9 bits; conditional E-value: 0.003 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lg + +A+ey +k le+ FUN_002329-T1 354 AYGSLGNAYQSLGVFRKAIEYHKKHLEI 381 899*****************97776665 PP == domain 11 score: 14.4 bits; conditional E-value: 4.9e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y+ lgd+ +A+ey ek le+ FUN_002329-T1 394 AYGSLGNAYQLLGDFRKAIEYHEKHLEI 421 89*******************9987776 PP == domain 12 score: 15.7 bits; conditional E-value: 2e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ y ek le+ FUN_002329-T1 433 RAYGSLGNAYQSLGDFRKAIDYHEKHLEI 461 89********************8887776 PP == domain 13 score: 4.5 bits; conditional E-value: 0.073 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay l ++y++lg + +A+ey +k le+ FUN_002329-T1 474 AYGSLVNAYQSLGVFRKAIEYHKKHLEI 501 8999*****************8776665 PP == domain 14 score: 14.4 bits; conditional E-value: 4.9e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y+ lgd+ +A+ey ek le+ FUN_002329-T1 514 AYGSLGNAYQLLGDFRKAIEYHEKHLEI 541 89*******************9987776 PP == domain 15 score: 15.0 bits; conditional E-value: 3.2e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ y ek le+ FUN_002329-T1 553 KAYGSLGNAYQSLGDFGKAIDYHEKHLEI 581 69********************8887776 PP == domain 16 score: 9.6 bits; conditional E-value: 0.0017 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lg + +A+ey ek le+ FUN_002329-T1 594 AYGSLGNAYQSLGVFRKAIEYHEKHLEI 621 899******************9887776 PP == domain 17 score: 12.9 bits; conditional E-value: 0.00015 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y+ lgd+ +A+e+ ek le+ FUN_002329-T1 634 AYGSLGNAYQLLGDFRKAIEFHEKHLEI 661 89******************98887766 PP == domain 18 score: 17.3 bits; conditional E-value: 5.7e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ey ek le+ FUN_002329-T1 673 KAYGSLGNAYRSLGDFRKAIEYHEKHLEI 701 69********************9987776 PP == domain 19 score: 17.2 bits; conditional E-value: 6.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ey ek le+ FUN_002329-T1 713 KAYGSLGNAYQSLGDFRKAIEYHEKHLEI 741 69********************9987776 PP == domain 20 score: 15.2 bits; conditional E-value: 2.8e-05 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay lG++y++lgd+ +A+ey FUN_002329-T1 754 AYGSLGNAYKSLGDFRKAIEY 774 89******************9 PP == domain 21 score: 16.6 bits; conditional E-value: 9.8e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG +y++lgd+ +A+ey +k le+ FUN_002329-T1 793 RAYGNLGIAYQSLGDFRKAIEYHKKHLEI 821 89********************8876665 PP == domain 22 score: 14.5 bits; conditional E-value: 4.5e-05 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay lG++y++lgd+ +A+ey FUN_002329-T1 834 AYGSLGNAYQSLGDFRKAIEY 854 89******************9 PP == domain 23 score: 14.9 bits; conditional E-value: 3.4e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay +lG +y++lgd+ +A+ey +k le+ FUN_002329-T1 873 RAYGHLGIAYQSLGDFRKAIEYHKKHLEI 901 89********************8876665 PP == domain 24 score: 14.5 bits; conditional E-value: 4.5e-05 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay lG++y++lgd+ +A+ey FUN_002329-T1 914 AYGSLGNAYQSLGDFRKAIEY 934 89******************9 PP == domain 25 score: 16.6 bits; conditional E-value: 9.8e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG +y++lgd+ +A+ey +k le+ FUN_002329-T1 953 RAYGNLGIAYQSLGDFRKAIEYHKKHLEI 981 89********************8876665 PP == domain 26 score: 14.5 bits; conditional E-value: 4.5e-05 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay lG++y++lgd+ +A+ey FUN_002329-T1 994 AYGSLGNAYQSLGDFRKAIEY 1014 89******************9 PP == domain 27 score: 16.6 bits; conditional E-value: 9.8e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG +y++lgd+ +A+ey +k le+ FUN_002329-T1 1033 RAYGNLGIAYQSLGDFRKAIEYHKKHLEI 1061 89********************8876665 PP == domain 28 score: 22.0 bits; conditional E-value: 1.8e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay nlG +y++lgd+ +A+ey ek+le++ FUN_002329-T1 1074 AYGNLGTAYRSLGDFRKAIEYHEKSLEIA 1102 9*************************995 PP == domain 29 score: 5.3 bits; conditional E-value: 0.043 TPR_8 3 ayynlGliylklgdyeeAk 21 a++n+G++y lg++e+A FUN_002329-T1 1114 AHHNIGNAYFCLGQFENAL 1132 689**************95 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.5 0.0039 3.5 3 23 .. 34 54 .. 32 62 .. 0.91 2 ! 12.9 0.2 0.00014 0.13 3 23 .. 74 94 .. 72 101 .. 0.92 3 ! 10.9 0.1 0.00063 0.57 3 23 .. 114 134 .. 112 141 .. 0.90 4 ! 11.1 0.2 0.00055 0.5 3 23 .. 154 174 .. 152 174 .. 0.92 5 ! 11.9 0.1 0.0003 0.28 2 28 .. 193 219 .. 192 223 .. 0.84 6 ! 12.2 0.1 0.00025 0.23 3 23 .. 234 254 .. 232 254 .. 0.94 7 ! 17.4 0.1 5.2e-06 0.0047 3 32 .. 274 303 .. 273 305 .. 0.93 8 ! 12.5 0.1 0.0002 0.19 3 23 .. 314 334 .. 312 341 .. 0.93 9 ? 3.8 0.1 0.12 1.1e+02 8 30 .. 352 374 .. 350 378 .. 0.56 10 ! 11.4 0.3 0.00044 0.4 3 23 .. 394 414 .. 392 421 .. 0.91 11 ! 10.8 0.1 0.00069 0.63 2 23 .. 433 454 .. 432 461 .. 0.91 12 ! 11.4 0.3 0.00044 0.4 3 23 .. 514 534 .. 512 541 .. 0.91 13 ! 10.4 0.1 0.00096 0.87 2 23 .. 553 574 .. 552 581 .. 0.91 14 ? 4.1 0.1 0.098 90 8 30 .. 592 614 .. 589 618 .. 0.60 15 ! 10.1 0.2 0.0012 1.1 3 23 .. 634 654 .. 632 660 .. 0.91 16 ! 12.6 0.2 0.00019 0.17 2 23 .. 673 694 .. 672 701 .. 0.92 17 ! 11.9 0.2 0.0003 0.27 2 23 .. 713 734 .. 712 741 .. 0.92 18 ! 10.5 0.2 0.00086 0.78 3 23 .. 754 774 .. 752 774 .. 0.92 19 ! 12.9 0.3 0.00015 0.14 2 23 .. 793 814 .. 792 820 .. 0.95 20 ! 11.1 0.2 0.00055 0.5 3 23 .. 834 854 .. 832 854 .. 0.92 21 ! 10.9 0.2 0.00063 0.58 2 23 .. 873 894 .. 872 897 .. 0.93 22 ! 11.1 0.2 0.00055 0.5 3 23 .. 914 934 .. 912 934 .. 0.92 23 ! 12.9 0.2 0.00015 0.14 2 23 .. 953 974 .. 952 977 .. 0.94 24 ! 11.1 0.2 0.00055 0.5 3 23 .. 994 1014 .. 992 1014 .. 0.92 25 ! 12.9 0.2 0.00015 0.14 2 23 .. 1033 1054 .. 1032 1057 .. 0.94 26 ! 16.4 0.1 1.1e-05 0.0099 3 31 .. 1074 1102 .. 1072 1104 .. 0.93 27 ! 16.6 0.0 9.5e-06 0.0087 3 29 .. 1114 1140 .. 1112 1144 .. 0.91 28 ? -1.0 0.0 4.1 3.8e+03 10 26 .. 1173 1189 .. 1172 1192 .. 0.84 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0039 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nl++a lgd+ +A+e+ FUN_002329-T1 34 GYQNLAYAFQSLGDFRKAIEY 54 799****************98 PP == domain 2 score: 12.9 bits; conditional E-value: 0.00014 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 74 AYRSLGNAYQSLGDFRKAIEY 94 8999***************98 PP == domain 3 score: 10.9 bits; conditional E-value: 0.00063 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ lG+ay lgd+ +A+e+ FUN_002329-T1 114 VYGSLGNAYQSLGDFRKAIEY 134 56779**************98 PP == domain 4 score: 11.1 bits; conditional E-value: 0.00055 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 154 AYGSLGNAYQSLGDFRKAIEY 174 7888***************98 PP == domain 5 score: 11.9 bits; conditional E-value: 0.0003 TPR_2 2 ealynlGlayyklgdyeeAleayekAl 28 +a+ lG ay+ lgd+ +A+e+ ek l FUN_002329-T1 193 RAYGSLGIAYRSLGDFRKAIEYHEKDL 219 57889****************966655 PP == domain 6 score: 12.2 bits; conditional E-value: 0.00025 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+ +A+e+ FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEY 254 799****************98 PP == domain 7 score: 17.4 bits; conditional E-value: 5.2e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a+ nlG ay+ lgd+ +A+e+ ek+le++ FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIEYHEKCLEIAK 303 789************************986 PP == domain 8 score: 12.5 bits; conditional E-value: 0.0002 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+++ FUN_002329-T1 314 AYGNLGNAYQSLGDFGKAIDY 334 899****************98 PP == domain 9 score: 3.8 bits; conditional E-value: 0.12 TPR_2 8 GlayyklgdyeeAleayekAlel 30 G+ay lg+ + l ++kA+e+ FUN_002329-T1 352 GNAYGSLGNAYQSLGVFRKAIEY 374 55555555555555555555554 PP == domain 10 score: 11.4 bits; conditional E-value: 0.00044 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 394 AYGSLGNAYQLLGDFRKAIEY 414 7888***************98 PP == domain 11 score: 10.8 bits; conditional E-value: 0.00069 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ay lgd+ +A+++ FUN_002329-T1 433 RAYGSLGNAYQSLGDFRKAIDY 454 57889***************98 PP == domain 12 score: 11.4 bits; conditional E-value: 0.00044 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 514 AYGSLGNAYQLLGDFRKAIEY 534 7888***************98 PP == domain 13 score: 10.4 bits; conditional E-value: 0.00096 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ay lgd+ +A+++ FUN_002329-T1 553 KAYGSLGNAYQSLGDFGKAIDY 574 68889***************98 PP == domain 14 score: 4.1 bits; conditional E-value: 0.098 TPR_2 8 GlayyklgdyeeAleayekAlel 30 G+ay lg+ + l ++kA+e+ FUN_002329-T1 592 GNAYGSLGNAYQSLGVFRKAIEY 614 56666666666666666666665 PP == domain 15 score: 10.1 bits; conditional E-value: 0.0012 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 634 AYGSLGNAYQLLGDFRKAIEF 654 7888***************85 PP == domain 16 score: 12.6 bits; conditional E-value: 0.00019 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ay+ lgd+ +A+e+ FUN_002329-T1 673 KAYGSLGNAYRSLGDFRKAIEY 694 68889***************98 PP == domain 17 score: 11.9 bits; conditional E-value: 0.0003 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ay lgd+ +A+e+ FUN_002329-T1 713 KAYGSLGNAYQSLGDFRKAIEY 734 68889***************98 PP == domain 18 score: 10.5 bits; conditional E-value: 0.00086 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 754 AYGSLGNAYKSLGDFRKAIEY 774 7888***************98 PP == domain 19 score: 12.9 bits; conditional E-value: 0.00015 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ nlG ay lgd+ +A+e+ FUN_002329-T1 793 RAYGNLGIAYQSLGDFRKAIEY 814 6899****************98 PP == domain 20 score: 11.1 bits; conditional E-value: 0.00055 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 834 AYGSLGNAYQSLGDFRKAIEY 854 7888***************98 PP == domain 21 score: 10.9 bits; conditional E-value: 0.00063 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG ay lgd+ +A+e+ FUN_002329-T1 873 RAYGHLGIAYQSLGDFRKAIEY 894 68999***************98 PP == domain 22 score: 11.1 bits; conditional E-value: 0.00055 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 914 AYGSLGNAYQSLGDFRKAIEY 934 7888***************98 PP == domain 23 score: 12.9 bits; conditional E-value: 0.00015 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ nlG ay lgd+ +A+e+ FUN_002329-T1 953 RAYGNLGIAYQSLGDFRKAIEY 974 6899****************98 PP == domain 24 score: 11.1 bits; conditional E-value: 0.00055 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002329-T1 994 AYGSLGNAYQSLGDFRKAIEY 1014 7888***************98 PP == domain 25 score: 12.9 bits; conditional E-value: 0.00015 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ nlG ay lgd+ +A+e+ FUN_002329-T1 1033 RAYGNLGIAYQSLGDFRKAIEY 1054 6899****************98 PP == domain 26 score: 16.4 bits; conditional E-value: 1.1e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG ay+ lgd+ +A+e+ ek+le++ FUN_002329-T1 1074 AYGNLGTAYRSLGDFRKAIEYHEKSLEIA 1102 899******************99999985 PP == domain 27 score: 16.6 bits; conditional E-value: 9.5e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAle 29 a++n G+ay+ lg++e Al+ + A+e FUN_002329-T1 1114 AHHNIGNAYFCLGQFENALDKFGSAVE 1140 89********************98876 PP == domain 28 score: -1.0 bits; conditional E-value: 4.1 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002329-T1 1173 SLLRIGKIDEALFAADE 1189 67899*******98776 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 167.7 0.0 5.9e-52 5.4e-49 8 291 .] 1329 1591 .. 1324 1591 .. 0.88 Alignments for each domain: == domain 1 score: 167.7 bits; conditional E-value: 5.9e-52 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ +Lviv dgaL +P++a ++ i ++ps+++ +s++++ ++ a l+vgnp+ + k FUN_002329-T1 1329 YDAVIGPIEDLL-GPEDDELVIVSDGALCFIPWAAVIESI---------RIRIVPSLKSyqlISSVPKGYHKKTGA--LLVGNPCLEQ----LK 1406 899****99997.77777*****************88886.........466666655422255555555555555..******9774....35 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 + lp +++E++++a++l+ +l+g++at+ ++++ + ++++++H+a+Hg + ++L++ n + ed L++++++ FUN_002329-T1 1407 NPLHALPCAQKEVEMIAAILKN---TPLVGKQATKAEVMKRM-SSVGLIHIAAHGNEV-----TGQIALSP-NPGwtqfpkeEDYILKMSDVQA 1490 55699***************77...8***************9.************988.....88899974.4445889998************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002329-T1 1491 ANLR-ARLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATMKFMKRFYQHLKEGKTASAAVHQSMKSLRESEE----FSE 1579 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002329-T1 1580 MWYWAPFQLIGD 1591 ***********7 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.1 0.066 60 28 75 .. 14 64 .. 7 68 .. 0.68 2 ? 5.0 0.0 0.04 36 44 78 .. 76 107 .. 67 109 .. 0.81 3 ! 8.2 0.0 0.004 3.6 39 76 .. 108 145 .. 105 149 .. 0.88 4 ? 4.3 0.0 0.067 61 45 73 .. 154 182 .. 145 188 .. 0.84 5 ? 5.3 0.0 0.032 29 41 76 .. 190 225 .. 183 227 .. 0.86 6 ? 2.6 0.1 0.22 2e+02 47 74 .. 236 263 .. 231 268 .. 0.87 7 ! 7.2 0.0 0.0082 7.5 47 76 .. 276 305 .. 270 309 .. 0.92 8 ? 1.6 0.0 0.47 4.3e+02 46 78 .. 315 347 .. 306 349 .. 0.87 9 ? 5.8 0.0 0.023 21 44 76 .. 353 385 .. 343 388 .. 0.86 10 ? 4.4 0.0 0.059 54 46 78 .. 395 427 .. 386 429 .. 0.88 11 ! 7.1 0.0 0.0089 8.1 38 78 .. 427 467 .. 423 469 .. 0.88 12 ! 7.7 0.0 0.0058 5.3 46 76 .. 475 505 .. 466 509 .. 0.89 13 ? 4.4 0.0 0.059 54 46 78 .. 515 547 .. 506 549 .. 0.88 14 ? 3.0 0.0 0.17 1.6e+02 40 78 .. 549 587 .. 544 589 .. 0.85 15 ? 5.0 0.0 0.041 37 46 76 .. 595 625 .. 585 629 .. 0.87 16 ? 6.5 0.1 0.014 13 46 78 .. 635 667 .. 627 669 .. 0.88 17 ! 6.9 0.0 0.01 9.1 41 78 .. 670 707 .. 665 709 .. 0.86 18 ? 6.7 0.1 0.011 10 40 76 .. 709 745 .. 704 749 .. 0.86 19 ? 3.8 0.0 0.091 83 46 73 .. 755 782 .. 746 788 .. 0.87 20 ? 5.4 0.1 0.03 28 41 75 .. 790 824 .. 783 828 .. 0.85 21 ? 4.1 0.0 0.078 71 46 73 .. 835 862 .. 823 868 .. 0.86 22 ? 6.7 0.1 0.012 11 41 76 .. 870 905 .. 862 908 .. 0.86 23 ? 3.9 0.0 0.086 79 46 73 .. 915 942 .. 906 948 .. 0.87 24 ? 6.1 0.0 0.017 16 41 76 .. 950 985 .. 943 989 .. 0.86 25 ? 3.9 0.0 0.086 78 46 73 .. 995 1022 .. 985 1027 .. 0.87 26 ! 7.5 0.0 0.0065 5.9 41 77 .. 1030 1066 .. 1022 1069 .. 0.87 27 ? 5.8 0.0 0.022 20 46 76 .. 1075 1105 .. 1067 1108 .. 0.90 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.066 Rapsyn_N 28 vWrkvlkktsdredk...frllGylitahsemGkykealefslaqlniaee 75 k lk t + +d+ + l a +G ++ a+e+ + l+ia e FUN_002329-T1 14 YHEKHLKITMEVGDRageEKGYQNLAYAFQSLGDFRKAIEYHEKHLEIAIE 64 5555566555444431003334457788999***************99977 PP == domain 2 score: 5.0 bits; conditional E-value: 0.04 Rapsyn_N 44 rllGylitahsemGkykealefslaqlniaeeled 78 r lG +a+ +G ++ a+e+ + l+ia e+ d FUN_002329-T1 76 RSLG---NAYQSLGDFRKAIEYHEKHLEIAIEVGD 107 5555...567789*****************99865 PP == domain 3 score: 8.2 bits; conditional E-value: 0.004 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaeel 76 r + ++ G l +a+ +G ++ a+e+ + l+ia e+ FUN_002329-T1 108 RVGEGNVYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 145 55666899**************************9987 PP == domain 4 score: 4.3 bits; conditional E-value: 0.067 Rapsyn_N 45 llGylitahsemGkykealefslaqlnia 73 G l +a+ +G ++ a+e+ + l+ia FUN_002329-T1 154 AYGSLGNAYQSLGDFRKAIEYHAKHLEIA 182 5789999***************9999998 PP == domain 5 score: 5.3 bits; conditional E-value: 0.032 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaeel 76 + r G l a+ +G ++ a+e+ + l+ia e+ FUN_002329-T1 190 GEGRAYGSLGIAYRSLGDFRKAIEYHEKDLEIAIEV 225 55677899999*********************9885 PP == domain 6 score: 2.6 bits; conditional E-value: 0.22 Rapsyn_N 47 GylitahsemGkykealefslaqlniae 74 G l a+ +G ++ a+e+ + l+ia FUN_002329-T1 236 GNLGVAYQSLGDFRKAIEYHAKHLEIAI 263 677889999***********99999985 PP == domain 7 score: 7.2 bits; conditional E-value: 0.0082 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l ta+ +G ++ a+e+ + l+ia+e+ FUN_002329-T1 276 GNLGTAYRSLGDFRKAIEYHEKCLEIAKEV 305 88999***********************97 PP == domain 8 score: 1.6 bits; conditional E-value: 0.47 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G + a+++ + l+ia e+ d FUN_002329-T1 315 YGNLGNAYQSLGDFGKAIDYHEKHLEIAIEVGD 347 5788899999*****************999865 PP == domain 9 score: 5.8 bits; conditional E-value: 0.023 Rapsyn_N 44 rllGylitahsemGkykealefslaqlniaeel 76 + G l +a+ +G ++ a+e+ ++ l+ia e+ FUN_002329-T1 353 NAYGSLGNAYQSLGVFRKAIEYHKKHLEIAIEV 385 56799999*********************9886 PP == domain 10 score: 4.4 bits; conditional E-value: 0.059 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002329-T1 395 YGSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGD 427 5888999999******************99865 PP == domain 11 score: 7.1 bits; conditional E-value: 0.0089 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeeled 78 dr + r G l +a+ +G ++ a+++ + l+ia e+ d FUN_002329-T1 427 DRVGEGRAYGSLGNAYQSLGDFRKAIDYHEKHLEIAIEVGD 467 5666778899**************************99865 PP == domain 12 score: 7.7 bits; conditional E-value: 0.0058 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l++a+ +G ++ a+e+ ++ l+ia e+ FUN_002329-T1 475 YGSLVNAYQSLGVFRKAIEYHKKHLEIAIEV 505 699************************9886 PP == domain 13 score: 4.4 bits; conditional E-value: 0.059 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002329-T1 515 YGSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGD 547 5888999999******************99865 PP == domain 14 score: 3.0 bits; conditional E-value: 0.17 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaeeled 78 + + G l +a+ +G + a+++ + l+ia e+ d FUN_002329-T1 549 VGEGKAYGSLGNAYQSLGDFGKAIDYHEKHLEIAIEVGD 587 555677899999**********************99865 PP == domain 15 score: 5.0 bits; conditional E-value: 0.041 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002329-T1 595 YGSLGNAYQSLGVFRKAIEYHEKHLEIAIEV 625 688999*********************9886 PP == domain 16 score: 6.5 bits; conditional E-value: 0.014 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+ef + l+ia e+ d FUN_002329-T1 635 YGSLGNAYQLLGDFRKAIEFHEKHLEIAIEVGD 667 5888899999******************99865 PP == domain 17 score: 6.9 bits; conditional E-value: 0.01 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaeeled 78 + + G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002329-T1 670 GEGKAYGSLGNAYRSLGDFRKAIEYHEKHLEIAIEVGD 707 5556789999***********************99865 PP == domain 18 score: 6.7 bits; conditional E-value: 0.011 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaeel 76 + + G l +a+ +G ++ a+e+ + l+ia e+ FUN_002329-T1 709 VGEGKAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 745 55667789999**********************9886 PP == domain 19 score: 3.8 bits; conditional E-value: 0.091 Rapsyn_N 46 lGylitahsemGkykealefslaqlnia 73 G l +a+ +G ++ a+e+ + l+ia FUN_002329-T1 755 YGSLGNAYKSLGDFRKAIEYHAKHLEIA 782 688999***************9999998 PP == domain 20 score: 5.4 bits; conditional E-value: 0.03 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaee 75 + r G l a+ +G ++ a+e+ ++ l+ia e FUN_002329-T1 790 GEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIAIE 824 55577899999********************9977 PP == domain 21 score: 4.1 bits; conditional E-value: 0.078 Rapsyn_N 46 lGylitahsemGkykealefslaqlnia 73 G l +a+ +G ++ a+e+ + l+ia FUN_002329-T1 835 YGSLGNAYQSLGDFRKAIEYHAKHLEIA 862 688999***************9999998 PP == domain 22 score: 6.7 bits; conditional E-value: 0.012 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaeel 76 + r G l a+ +G ++ a+e+ ++ l+ia e+ FUN_002329-T1 870 GEGRAYGHLGIAYQSLGDFRKAIEYHKKHLEIAIEV 905 55678899999*********************9886 PP == domain 23 score: 3.9 bits; conditional E-value: 0.086 Rapsyn_N 46 lGylitahsemGkykealefslaqlnia 73 G l +a+ +G ++ a+e+ + l+ia FUN_002329-T1 915 YGSLGNAYQSLGDFRKAIEYHAKHLEIA 942 688999***************9999998 PP == domain 24 score: 6.1 bits; conditional E-value: 0.017 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaeel 76 + r G l a+ +G ++ a+e+ ++ l+ia e+ FUN_002329-T1 950 GEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEV 985 55577899999*********************9886 PP == domain 25 score: 3.9 bits; conditional E-value: 0.086 Rapsyn_N 46 lGylitahsemGkykealefslaqlnia 73 G l +a+ +G ++ a+e+ + l+ia FUN_002329-T1 995 YGSLGNAYQSLGDFRKAIEYHAKHLEIA 1022 688999***************9999998 PP == domain 26 score: 7.5 bits; conditional E-value: 0.0065 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaeele 77 + r G l a+ +G ++ a+e+ ++ l+ia e++ FUN_002329-T1 1030 GEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEVD 1066 55677899999**********************9987 PP == domain 27 score: 5.8 bits; conditional E-value: 0.022 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l ta+ +G ++ a+e+ + l+ia e+ FUN_002329-T1 1075 YGNLGTAYRSLGDFRKAIEYHEKSLEIAIEV 1105 68899**********************9886 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.1 0.12 1.1e+02 15 34 .] 34 53 .. 32 53 .. 0.92 2 ? 4.1 0.1 0.11 97 14 34 .] 73 93 .. 71 93 .. 0.91 3 ? 3.9 0.0 0.13 1.2e+02 14 34 .] 113 133 .. 111 133 .. 0.90 4 ? 5.1 0.1 0.052 47 14 34 .] 153 173 .. 151 173 .. 0.92 5 ? 3.7 0.0 0.14 1.3e+02 15 34 .] 194 213 .. 191 213 .. 0.91 6 ? 6.4 0.0 0.019 18 15 34 .] 234 253 .. 231 253 .. 0.92 7 ? 5.8 0.0 0.03 27 15 34 .] 274 293 .. 273 293 .. 0.93 8 ? 6.8 0.0 0.014 13 14 33 .. 313 332 .. 311 333 .. 0.92 9 ? -0.7 0.0 3.7 3.4e+03 14 27 .. 353 366 .. 352 381 .. 0.71 10 ? 5.2 0.1 0.046 42 14 34 .] 393 413 .. 391 413 .. 0.92 11 ? 3.9 0.0 0.12 1.1e+02 15 33 .. 434 452 .. 431 453 .. 0.91 12 ? 5.2 0.1 0.046 42 14 34 .] 513 533 .. 511 533 .. 0.92 13 ? 4.4 0.0 0.089 81 14 33 .. 553 572 .. 551 573 .. 0.92 14 ? -0.7 0.0 3.8 3.5e+03 14 27 .. 593 606 .. 591 618 .. 0.78 15 ? 5.2 0.1 0.046 42 14 34 .] 633 653 .. 631 653 .. 0.92 16 ? 4.9 0.0 0.058 53 14 34 .] 673 693 .. 671 693 .. 0.92 17 ? 4.9 0.0 0.058 53 14 34 .] 713 733 .. 711 733 .. 0.92 18 ? 4.9 0.0 0.059 54 14 34 .] 753 773 .. 751 773 .. 0.92 19 ? 6.6 0.0 0.017 15 15 34 .] 794 813 .. 791 813 .. 0.92 20 ? 5.1 0.1 0.052 47 14 34 .] 833 853 .. 831 853 .. 0.92 21 ? 3.1 0.0 0.23 2.1e+02 15 34 .] 874 893 .. 871 893 .. 0.91 22 ? 5.1 0.1 0.052 47 14 34 .] 913 933 .. 911 933 .. 0.92 23 ? 6.6 0.0 0.017 15 15 34 .] 954 973 .. 951 973 .. 0.92 24 ? 5.1 0.1 0.052 47 14 34 .] 993 1013 .. 991 1013 .. 0.92 25 ? 6.6 0.0 0.017 15 15 34 .] 1034 1053 .. 1031 1053 .. 0.92 26 ? 7.1 0.0 0.012 11 14 34 .] 1073 1093 .. 1071 1093 .. 0.93 27 ? 2.6 0.1 0.32 3e+02 15 33 .. 1114 1132 .. 1112 1133 .. 0.88 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.12 TPR_17 15 ayynLArlllnnGqleeAlq 34 y+nLA++ + +G++ +A++ FUN_002329-T1 34 GYQNLAYAFQSLGDFRKAIE 53 69***************985 PP == domain 2 score: 4.1 bits; conditional E-value: 0.11 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 73 NAYRSLGNAYQSLGDFRKAIE 93 6999**************985 PP == domain 3 score: 3.9 bits; conditional E-value: 0.13 TPR_17 14 dayynLArlllnnGqleeAlq 34 ++y L+++++ +G++ +A++ FUN_002329-T1 113 NVYGSLGNAYQSLGDFRKAIE 133 57999*************985 PP == domain 4 score: 5.1 bits; conditional E-value: 0.052 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 153 NAYGSLGNAYQSLGDFRKAIE 173 79****************985 PP == domain 5 score: 3.7 bits; conditional E-value: 0.14 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002329-T1 194 AYGSLGIAYRSLGDFRKAIE 213 899**************985 PP == domain 6 score: 6.4 bits; conditional E-value: 0.019 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIE 253 8****************985 PP == domain 7 score: 5.8 bits; conditional E-value: 0.03 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIE 293 89***************985 PP == domain 8 score: 6.8 bits; conditional E-value: 0.014 TPR_17 14 dayynLArlllnnGqleeAl 33 ay nL+++++ +G++ +A+ FUN_002329-T1 313 SAYGNLGNAYQSLGDFGKAI 332 59**************9997 PP == domain 9 score: -0.7 bits; conditional E-value: 3.7 TPR_17 14 dayynLArlllnnG 27 +ay L+++++ +G FUN_002329-T1 353 NAYGSLGNAYQSLG 366 57888888888776 PP == domain 10 score: 5.2 bits; conditional E-value: 0.046 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 393 NAYGSLGNAYQLLGDFRKAIE 413 79****************985 PP == domain 11 score: 3.9 bits; conditional E-value: 0.12 TPR_17 15 ayynLArlllnnGqleeAl 33 ay L+++++ +G++ +A+ FUN_002329-T1 434 AYGSLGNAYQSLGDFRKAI 452 899************9997 PP == domain 12 score: 5.2 bits; conditional E-value: 0.046 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 513 NAYGSLGNAYQLLGDFRKAIE 533 79****************985 PP == domain 13 score: 4.4 bits; conditional E-value: 0.089 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay L+++++ +G++ +A+ FUN_002329-T1 553 KAYGSLGNAYQSLGDFGKAI 572 699*************9997 PP == domain 14 score: -0.7 bits; conditional E-value: 3.8 TPR_17 14 dayynLArlllnnG 27 +ay L+++++ +G FUN_002329-T1 593 NAYGSLGNAYQSLG 606 68999999998887 PP == domain 15 score: 5.2 bits; conditional E-value: 0.046 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 633 NAYGSLGNAYQLLGDFRKAIE 653 79****************985 PP == domain 16 score: 4.9 bits; conditional E-value: 0.058 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 673 KAYGSLGNAYRSLGDFRKAIE 693 699***************985 PP == domain 17 score: 4.9 bits; conditional E-value: 0.058 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 713 KAYGSLGNAYQSLGDFRKAIE 733 699***************985 PP == domain 18 score: 4.9 bits; conditional E-value: 0.059 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 753 NAYGSLGNAYKSLGDFRKAIE 773 79****************985 PP == domain 19 score: 6.6 bits; conditional E-value: 0.017 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002329-T1 794 AYGNLGIAYQSLGDFRKAIE 813 9****************985 PP == domain 20 score: 5.1 bits; conditional E-value: 0.052 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 833 NAYGSLGNAYQSLGDFRKAIE 853 79****************985 PP == domain 21 score: 3.1 bits; conditional E-value: 0.23 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002329-T1 874 AYGHLGIAYQSLGDFRKAIE 893 8999*************985 PP == domain 22 score: 5.1 bits; conditional E-value: 0.052 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 913 NAYGSLGNAYQSLGDFRKAIE 933 79****************985 PP == domain 23 score: 6.6 bits; conditional E-value: 0.017 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002329-T1 954 AYGNLGIAYQSLGDFRKAIE 973 9****************985 PP == domain 24 score: 5.1 bits; conditional E-value: 0.052 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002329-T1 993 NAYGSLGNAYQSLGDFRKAIE 1013 79****************985 PP == domain 25 score: 6.6 bits; conditional E-value: 0.017 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002329-T1 1034 AYGNLGIAYQSLGDFRKAIE 1053 9****************985 PP == domain 26 score: 7.1 bits; conditional E-value: 0.012 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002329-T1 1073 NAYGNLGTAYRSLGDFRKAIE 1093 79****************985 PP == domain 27 score: 2.6 bits; conditional E-value: 0.32 TPR_17 15 ayynLArlllnnGqleeAl 33 a++n ++++ +Gq+e Al FUN_002329-T1 1114 AHHNIGNAYFCLGQFENAL 1132 799***********99886 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.046 42 4 29 .. 35 60 .. 32 64 .. 0.89 2 ! 8.4 0.0 0.0063 5.7 2 29 .. 73 100 .. 72 102 .. 0.91 3 ? 5.3 0.0 0.065 59 6 29 .. 117 140 .. 113 142 .. 0.88 4 ? 4.3 0.0 0.14 1.3e+02 5 28 .. 156 179 .. 153 182 .. 0.83 5 ? 3.5 0.0 0.26 2.4e+02 6 25 .. 197 216 .. 193 217 .. 0.84 6 ? 1.9 0.1 0.85 7.7e+02 7 28 .. 238 259 .. 233 262 .. 0.83 7 ! 8.5 0.0 0.006 5.4 7 31 .. 278 302 .. 273 306 .. 0.88 8 ? 4.2 0.0 0.15 1.4e+02 6 29 .. 317 340 .. 313 342 .. 0.87 9 ? -0.5 0.0 5 4.6e+03 6 29 .. 357 380 .. 353 382 .. 0.82 10 ? 4.9 0.1 0.091 83 5 29 .. 396 420 .. 393 422 .. 0.86 11 ? 4.9 0.0 0.087 80 5 29 .. 436 460 .. 433 463 .. 0.86 12 ? -0.6 0.0 5.4 4.9e+03 6 29 .. 477 500 .. 473 502 .. 0.84 13 ? 4.9 0.1 0.091 83 5 29 .. 516 540 .. 513 542 .. 0.86 14 ? 4.5 0.0 0.12 1.1e+02 6 29 .. 557 580 .. 553 583 .. 0.87 15 ? 0.3 0.0 2.6 2.4e+03 5 29 .. 596 620 .. 593 622 .. 0.85 16 ? 3.2 0.0 0.3 2.7e+02 5 29 .. 636 660 .. 633 662 .. 0.84 17 ? 7.2 0.0 0.016 14 6 29 .. 677 700 .. 673 702 .. 0.87 18 ? 5.5 0.0 0.056 52 6 29 .. 717 740 .. 713 742 .. 0.87 19 ? 4.7 0.0 0.11 97 5 28 .. 756 779 .. 753 782 .. 0.83 20 ? 2.7 0.0 0.45 4.1e+02 6 29 .. 797 820 .. 793 823 .. 0.84 21 ? 4.3 0.0 0.14 1.3e+02 5 28 .. 836 859 .. 833 862 .. 0.83 22 ? 3.0 0.0 0.38 3.4e+02 6 29 .. 877 900 .. 873 902 .. 0.84 23 ? 4.3 0.0 0.14 1.3e+02 5 28 .. 916 939 .. 913 942 .. 0.83 24 ? 2.7 0.0 0.47 4.2e+02 6 29 .. 957 980 .. 953 982 .. 0.84 25 ? 4.3 0.0 0.14 1.3e+02 5 28 .. 996 1019 .. 993 1022 .. 0.83 26 ? 2.7 0.0 0.47 4.2e+02 6 29 .. 1037 1060 .. 1033 1062 .. 0.84 27 ? 5.9 0.0 0.042 38 6 29 .. 1077 1100 .. 1073 1102 .. 0.86 28 ? 3.2 0.0 0.32 2.9e+02 7 32 .. 1118 1143 .. 1114 1150 .. 0.79 29 ? 2.6 0.1 0.47 4.3e+02 10 40 .. 1173 1202 .. 1170 1207 .. 0.74 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.046 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ la+a+ lGd+ +A+e+ e+ l+ FUN_002329-T1 35 YQNLAYAFQSLGDFRKAIEYHEKHLE 60 7889****************999876 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0063 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a++ l++a+ lGd+ +A+e+ e+ l+ FUN_002329-T1 73 NAYRSLGNAYQSLGDFRKAIEYHEKHLE 100 68999*****************998876 PP == domain 3 score: 5.3 bits; conditional E-value: 0.065 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002329-T1 117 SLGNAYQSLGDFRKAIEYHEKHLE 140 589***************998876 PP == domain 4 score: 4.3 bits; conditional E-value: 0.14 TPR_14 5 lalarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002329-T1 156 GSLGNAYQSLGDFRKAIEYHAKHL 179 5799**************987766 PP == domain 5 score: 3.5 bits; conditional E-value: 0.26 TPR_14 6 alarallalGdpdeAlelle 25 l+ a++ lGd+ +A+e+ e FUN_002329-T1 197 SLGIAYRSLGDFRKAIEYHE 216 6899************9866 PP == domain 6 score: 1.9 bits; conditional E-value: 0.85 TPR_14 7 larallalGdpdeAlelleral 28 l+ a+ lGd+ +A+e+ + l FUN_002329-T1 238 LGVAYQSLGDFRKAIEYHAKHL 259 7889************987766 PP == domain 7 score: 8.5 bits; conditional E-value: 0.006 TPR_14 7 larallalGdpdeAlelleralald 31 l+ a++ lGd+ +A+e+ e++l+ FUN_002329-T1 278 LGTAYRSLGDFRKAIEYHEKCLEIA 302 899******************9975 PP == domain 8 score: 4.2 bits; conditional E-value: 0.15 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+++ e+ l+ FUN_002329-T1 317 NLGNAYQSLGDFGKAIDYHEKHLE 340 5899**************998876 PP == domain 9 score: -0.5 bits; conditional E-value: 5 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lG + +A+e+ ++ l+ FUN_002329-T1 357 SLGNAYQSLGVFRKAIEYHKKHLE 380 6999************99887765 PP == domain 10 score: 4.9 bits; conditional E-value: 0.091 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002329-T1 396 GSLGNAYQLLGDFRKAIEYHEKHLE 420 5799***************998876 PP == domain 11 score: 4.9 bits; conditional E-value: 0.087 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+++ e+ l+ FUN_002329-T1 436 GSLGNAYQSLGDFRKAIDYHEKHLE 460 5799***************998876 PP == domain 12 score: -0.6 bits; conditional E-value: 5.4 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lG + +A+e+ ++ l+ FUN_002329-T1 477 SLVNAYQSLGVFRKAIEYHKKHLE 500 6999*************9888765 PP == domain 13 score: 4.9 bits; conditional E-value: 0.091 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002329-T1 516 GSLGNAYQLLGDFRKAIEYHEKHLE 540 5799***************998876 PP == domain 14 score: 4.5 bits; conditional E-value: 0.12 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+++ e+ l+ FUN_002329-T1 557 SLGNAYQSLGDFGKAIDYHEKHLE 580 699***************998876 PP == domain 15 score: 0.3 bits; conditional E-value: 2.6 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lG + +A+e+ e+ l+ FUN_002329-T1 596 GSLGNAYQSLGVFRKAIEYHEKHLE 620 56999*************9998876 PP == domain 16 score: 3.2 bits; conditional E-value: 0.3 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e e+ l+ FUN_002329-T1 636 GSLGNAYQLLGDFRKAIEFHEKHLE 660 5799**************9888776 PP == domain 17 score: 7.2 bits; conditional E-value: 0.016 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002329-T1 677 SLGNAYRSLGDFRKAIEYHEKHLE 700 699***************998876 PP == domain 18 score: 5.5 bits; conditional E-value: 0.056 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002329-T1 717 SLGNAYQSLGDFRKAIEYHEKHLE 740 699***************998876 PP == domain 19 score: 4.7 bits; conditional E-value: 0.11 TPR_14 5 lalarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002329-T1 756 GSLGNAYKSLGDFRKAIEYHAKHL 779 5799**************987766 PP == domain 20 score: 2.7 bits; conditional E-value: 0.45 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ ++ l+ FUN_002329-T1 797 NLGIAYQSLGDFRKAIEYHKKHLE 820 57889************9888776 PP == domain 21 score: 4.3 bits; conditional E-value: 0.14 TPR_14 5 lalarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002329-T1 836 GSLGNAYQSLGDFRKAIEYHAKHL 859 5799**************987766 PP == domain 22 score: 3.0 bits; conditional E-value: 0.38 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ ++ l+ FUN_002329-T1 877 HLGIAYQSLGDFRKAIEYHKKHLE 900 68899************9888776 PP == domain 23 score: 4.3 bits; conditional E-value: 0.14 TPR_14 5 lalarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002329-T1 916 GSLGNAYQSLGDFRKAIEYHAKHL 939 5799**************987766 PP == domain 24 score: 2.7 bits; conditional E-value: 0.47 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ ++ l+ FUN_002329-T1 957 NLGIAYQSLGDFRKAIEYHKKHLE 980 57889************9888776 PP == domain 25 score: 4.3 bits; conditional E-value: 0.14 TPR_14 5 lalarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002329-T1 996 GSLGNAYQSLGDFRKAIEYHAKHL 1019 5799**************987766 PP == domain 26 score: 2.7 bits; conditional E-value: 0.47 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ ++ l+ FUN_002329-T1 1037 NLGIAYQSLGDFRKAIEYHKKHLE 1060 57889************9888776 PP == domain 27 score: 5.9 bits; conditional E-value: 0.042 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a++ lGd+ +A+e+ e+ l+ FUN_002329-T1 1077 NLGTAYRSLGDFRKAIEYHEKSLE 1100 5899**************999876 PP == domain 28 score: 3.2 bits; conditional E-value: 0.32 TPR_14 7 larallalGdpdeAlelleralaldP 32 ++a++ lG+++ Al+ + +a++++ FUN_002329-T1 1118 IGNAYFCLGQFENALDKFGSAVETFN 1143 67899999999999999888888775 PP == domain 29 score: 2.6 bits; conditional E-value: 0.47 TPR_14 10 allalGdpdeAlelleralaldPddpeawla 40 ll+ G+ deAl +++++ a+ ++ +w++ FUN_002329-T1 1173 SLLRIGKIDEALFAADEGRAQ-TLSENLWIQ 1202 6899**************664.455555544 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.2 0.00034 0.31 13 143 .. 44 173 .. 32 182 .. 0.56 2 ! 8.8 0.0 0.0013 1.2 12 112 .. 123 224 .. 117 231 .. 0.91 3 ! 15.9 0.0 9.6e-06 0.0087 15 149 .. 206 339 .. 199 354 .. 0.81 4 ! 10.2 0.0 0.00049 0.45 40 186 .. 352 497 .. 321 509 .. 0.76 5 ! 6.2 0.0 0.0083 7.6 18 112 .. 489 584 .. 481 592 .. 0.83 6 ! 11.4 0.0 0.00022 0.2 15 151 .. 606 741 .. 598 751 .. 0.82 7 ? 2.3 0.0 0.12 1.1e+02 42 110 .. 714 782 .. 706 791 .. 0.73 8 ! 12.1 0.1 0.00013 0.12 12 151 .. 803 941 .. 798 954 .. 0.87 9 ! 10.7 0.1 0.00036 0.33 13 167 .. 884 1038 .. 874 1071 .. 0.74 10 ! 11.1 0.0 0.00026 0.24 12 152 .. 963 1102 .. 957 1109 .. 0.90 11 ! 7.8 0.0 0.0027 2.5 11 68 .. 1082 1140 .. 1078 1151 .. 0.88 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00034 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + + a+ +lG a++ +gd+ +A + ++ ++a + ++ + ++++ ++ G++++A+e ++ l FUN_002329-T1 44 SLGDFRKAIEYHEKHLEIAIEAGHRVGeGNAYRSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGDRVGEGNVYGSLGNAYQSLGDFRKAIEYHEKHL 139 445666666666666666666666665566666666666666666666666665555555555555555556666666666666666666666666 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeq 143 + a e + + g ++ +l++ + +d+ +A + FUN_002329-T1 140 EIAIEVSHRV--GEGNAYGSLGNAYQSLGDFRKAIE 173 6666554442..444555555555555555555544 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0013 TPR_MalT 12 vsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 s g++ +a+e+ ++ L++ e ++ + + a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ +r G++++A+e ++ FUN_002329-T1 123 QSLGDFRKAIEYHEKHLEIAIEVSHRVGeGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGSLGIAYRSLGDFRKAIEYHEKD 218 5779999************99999999889***********************999999999999999999********************99998 PP TPR_MalT 107 lqlaqe 112 l+ a e FUN_002329-T1 219 LEIAIE 224 888766 PP == domain 3 score: 15.9 bits; conditional E-value: 9.6e-06 TPR_MalT 15 geaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 g++ +a+e+ ++ L++ e + ++a+ +lG+a++ +gd+ +A + ++ ++a ++++ a+ ++ +r G++++A+e ++ l+ FUN_002329-T1 206 GDFRKAIEYHEKDLEIAIEVGYRVGeGVAYGNLGVAYQSLGDFRKAIEYHAKHLEIAIKIGHQVGEEGAYGNLGTAYRSLGDFRKAIEYHEKCLEI 301 566666666666666666555555458899****************************************************************** PP TPR_MalT 110 aqesklealplvgfllvgladLlyEwndLeeAeqhlqqgi 149 a+e +++ g ++ l++ + +d+ +A + ++ + FUN_002329-T1 302 AKEVSGRV--GEGSAYGNLGNAYQSLGDFGKAIDYHEKHL 339 ***99996..667778888888888888888855554444 PP == domain 4 score: 10.2 bits; conditional E-value: 0.00049 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 + a+ +lG a++ +g + +A + ++ ++a + ++ a+ ++++ ++ G++++A+e ++ l+ a e + + g ++ +l++ + FUN_002329-T1 352 GNAYGSLGNAYQSLGVFRKAIEYHKKHLEIAIEVGHRVGEGNAYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGDRV--GEGRAYGSLGNAYQSL 445 667788888888888888888888888888888888888888888999999999999999999999999999888885..7788888899999999 PP TPR_MalT 136 ndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqr 186 +d+ +A + ++ ++++ ++ ++ +ay l++ ++ G + A ++ ++ FUN_002329-T1 446 GDFRKAIDYHEKHLEIAIEVgDRVEEGNAYGSLVNAYQSLGVFRKAIEYHKK 497 9999998888888888888766677888888888888888887777776665 PP == domain 5 score: 6.2 bits; conditional E-value: 0.0083 TPR_MalT 18 eeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqe 112 +a+e+ ++ L++ e + + + a+ +lG a++l+gd+ +A + ++ ++a + ++ a+ ++++ ++ G++ +A++ ++ l+ a e FUN_002329-T1 489 RKAIEYHKKHLEIAIEVGHRVGeGNAYGSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGDRVGEGKAYGSLGNAYQSLGDFGKAIDYHEKHLEIAIE 584 5666666666666666666555578999***************9999999999999988888999********************99999998876 PP == domain 6 score: 11.4 bits; conditional E-value: 0.00022 TPR_MalT 15 geaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 g + +a+e+ ++ L++ e + + + a+ +lG a++l+gd+ +A + ++ ++a + ++ a+ ++++ +r G++++A+e ++ l+ FUN_002329-T1 606 GVFRKAIEYHEKHLEIAIEVGHRVGeGNAYGSLGNAYQLLGDFRKAIEFHEKHLEIAIEVGDRVGEGKAYGSLGNAYRSLGDFRKAIEYHEKHLEI 701 5566777777777777777776665688999****************9999999999999998889999*************************** PP TPR_MalT 110 aqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiql 151 a e + + g ++ +l++ + +d+ +A ++ ++ +++ FUN_002329-T1 702 AIEVGDRV--GEGKAYGSLGNAYQSLGDFRKAIEYHEKHLEI 741 *9999885..77888889999999999888887776666555 PP == domain 7 score: 2.3 bits; conditional E-value: 0.12 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ ++++ + G++++A+e + l+ a FUN_002329-T1 714 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYKSLGDFRKAIEYHAKHLEIA 782 667788888888888877777777777777777777777788888888888888888877666655555 PP == domain 8 score: 12.1 bits; conditional E-value: 0.00013 TPR_MalT 12 vsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 s g++ +a+e+ ++ L++ e + + + a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ ++ G++++A+e ++ FUN_002329-T1 803 QSLGDFRKAIEYHKKHLEIAIEAGHRVGeGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGHLGIAYQSLGDFRKAIEYHKKH 898 578999****************9999988**************************999999999999999************************** PP TPR_MalT 107 lqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiql 151 l+ a e + + g ++ +l++ + +d+ +A ++ + +++ FUN_002329-T1 899 LEIAIEVGHRV--GEGNAYGSLGNAYQSLGDFRKAIEYHAKHLEI 941 ****9998874..77888899999999999998886665554444 PP == domain 9 score: 10.7 bits; conditional E-value: 0.00036 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 s g++ +a+e+ ++ L++ e + + + a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ ++ ++ G++++A+e ++ FUN_002329-T1 884 SLGDFRKAIEYHKKHLEIAIEVGHRVGeGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLGDFRKAIEYHKK 977 6678888888888888888888777766888899999999999999999988888888888888888888899999999999999999999999 PP TPR_MalT 106 alqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvll 167 l+ a e + + g ++ +l++ + +d+ +A ++ + ++++ ++ + +ay l FUN_002329-T1 978 HLEIAIEVGHRV--GEGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVgHRVGEGRAYGNL 1038 999998887774..7778888888888888888888777666666666553334444455444 PP == domain 10 score: 11.1 bits; conditional E-value: 0.00026 TPR_MalT 12 vsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyq 104 s g++ +a+e+ ++ L++ e + + + a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ ++ ++ G++++A+e + FUN_002329-T1 963 QSLGDFRKAIEYHKKHLEIAIEVGHRVGeGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLGDFRKAIEYHK 1056 56789999999999999999998888877999********************9999999999999999999*********************** PP TPR_MalT 105 qalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 + l+ a e + + g ++ l+ ++ +d+ +A ++ +++++++ FUN_002329-T1 1057 KHLEIAIEVDYRV--GEGNAYGNLGTAYRSLGDFRKAIEYHEKSLEIA 1102 ********99995..888999999999999999999999999999887 PP == domain 11 score: 7.8 bits; conditional E-value: 0.0027 TPR_MalT 11 avsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaea 68 + s g++ +a+e+ ++ L++ e + a ++a+ + G a++++g++e+Al+ + +a + FUN_002329-T1 1082 YRSLGDFRKAIEYHEKSLEIAIEVGHRAGeGIAHHNIGNAYFCLGQFENALDKFGSAVE 1140 56789999************9999999878*********************99987765 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.34 3.1e+02 5 22 .. 37 54 .. 35 56 .. 0.92 2 ? 2.9 0.0 0.34 3.1e+02 6 22 .. 78 94 .. 73 97 .. 0.89 3 ? 2.4 0.0 0.49 4.5e+02 6 22 .. 118 134 .. 117 136 .. 0.93 4 ? 2.3 0.0 0.51 4.6e+02 6 22 .. 158 174 .. 157 175 .. 0.93 5 ? 2.9 0.0 0.33 3e+02 6 22 .. 198 214 .. 197 216 .. 0.93 6 ? 3.7 0.0 0.19 1.7e+02 6 22 .. 238 254 .. 237 254 .. 0.92 7 ? 4.5 0.0 0.11 97 6 25 .. 278 297 .. 277 301 .. 0.85 8 ? 0.9 0.0 1.5 1.3e+03 5 22 .. 317 334 .. 314 336 .. 0.91 9 ? -0.5 0.0 3.9 3.6e+03 9 30 .. 354 375 .. 352 378 .. 0.60 10 ? 2.6 0.0 0.4 3.6e+02 6 22 .. 398 414 .. 397 416 .. 0.93 11 ? 2.3 0.0 0.52 4.7e+02 6 22 .. 438 454 .. 437 456 .. 0.93 12 ? 2.6 0.0 0.4 3.6e+02 6 22 .. 518 534 .. 517 536 .. 0.93 13 ? -0.0 0.0 2.9 2.6e+03 6 22 .. 558 574 .. 557 575 .. 0.92 14 ? -0.9 0.0 5.3 4.8e+03 13 29 .. 598 614 .. 592 617 .. 0.53 15 ? 1.9 0.0 0.68 6.2e+02 6 21 .. 638 653 .. 637 654 .. 0.92 16 ? 2.8 0.0 0.36 3.3e+02 6 22 .. 678 694 .. 677 696 .. 0.93 17 ? 2.4 0.0 0.49 4.5e+02 6 22 .. 718 734 .. 717 736 .. 0.93 18 ? 2.1 0.0 0.61 5.6e+02 6 22 .. 758 774 .. 757 774 .. 0.92 19 ? 3.3 0.0 0.24 2.2e+02 5 22 .. 797 814 .. 794 815 .. 0.92 20 ? 2.3 0.0 0.51 4.6e+02 6 22 .. 838 854 .. 837 855 .. 0.93 21 ? 3.2 0.0 0.26 2.4e+02 5 22 .. 877 894 .. 874 894 .. 0.92 22 ? 2.3 0.0 0.51 4.6e+02 6 22 .. 918 934 .. 917 935 .. 0.93 23 ? 3.3 0.0 0.24 2.2e+02 5 22 .. 957 974 .. 954 975 .. 0.92 24 ? 2.3 0.0 0.51 4.6e+02 6 22 .. 998 1014 .. 997 1015 .. 0.93 25 ? 3.3 0.0 0.24 2.2e+02 5 22 .. 1037 1054 .. 1034 1055 .. 0.92 26 ? 3.5 0.0 0.22 2e+02 6 22 .. 1078 1094 .. 1077 1097 .. 0.92 27 ? 0.7 0.0 1.7 1.5e+03 5 29 .. 1117 1141 .. 1114 1142 .. 0.85 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.34 TPR_6 5 klalsylelgdkdeAkaa 22 +la++++ lgd+ +A+++ FUN_002329-T1 37 NLAYAFQSLGDFRKAIEY 54 69*************986 PP == domain 2 score: 2.9 bits; conditional E-value: 0.34 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 78 LGNAYQSLGDFRKAIEY 94 899***********986 PP == domain 3 score: 2.4 bits; conditional E-value: 0.49 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 118 LGNAYQSLGDFRKAIEY 134 799***********986 PP == domain 4 score: 2.3 bits; conditional E-value: 0.51 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 158 LGNAYQSLGDFRKAIEY 174 799***********986 PP == domain 5 score: 2.9 bits; conditional E-value: 0.33 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 198 LGIAYRSLGDFRKAIEY 214 799***********986 PP == domain 6 score: 3.7 bits; conditional E-value: 0.19 TPR_6 6 lalsylelgdkdeAkaa 22 l+++y+ lgd+ +A+++ FUN_002329-T1 238 LGVAYQSLGDFRKAIEY 254 9*************986 PP == domain 7 score: 4.5 bits; conditional E-value: 0.11 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd+ +A+++ ++ FUN_002329-T1 278 LGTAYRSLGDFRKAIEYHEK 297 89*************98555 PP == domain 8 score: 0.9 bits; conditional E-value: 1.5 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002329-T1 317 NLGNAYQSLGDFGKAIDY 334 589************986 PP == domain 9 score: -0.5 bits; conditional E-value: 3.9 TPR_6 9 sylelgdkdeAkaalqrlikkY 30 +y lg+ + + ++++ i+ + FUN_002329-T1 354 AYGSLGNAYQSLGVFRKAIEYH 375 5556666666666666666655 PP == domain 10 score: 2.6 bits; conditional E-value: 0.4 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 398 LGNAYQLLGDFRKAIEY 414 799***********986 PP == domain 11 score: 2.3 bits; conditional E-value: 0.52 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 438 LGNAYQSLGDFRKAIDY 454 799***********986 PP == domain 12 score: 2.6 bits; conditional E-value: 0.4 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 518 LGNAYQLLGDFRKAIEY 534 799***********986 PP == domain 13 score: -0.0 bits; conditional E-value: 2.9 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 558 LGNAYQSLGDFGKAIDY 574 799***********986 PP == domain 14 score: -0.9 bits; conditional E-value: 5.3 TPR_6 13 lgdkdeAkaalqrlikk 29 lg+ + + ++++ i+ FUN_002329-T1 598 LGNAYQSLGVFRKAIEY 614 55555555555555544 PP == domain 15 score: 1.9 bits; conditional E-value: 0.68 TPR_6 6 lalsylelgdkdeAka 21 l+ +y+ lgd+ +A++ FUN_002329-T1 638 LGNAYQLLGDFRKAIE 653 799***********97 PP == domain 16 score: 2.8 bits; conditional E-value: 0.36 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 678 LGNAYRSLGDFRKAIEY 694 799***********986 PP == domain 17 score: 2.4 bits; conditional E-value: 0.49 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 718 LGNAYQSLGDFRKAIEY 734 799***********986 PP == domain 18 score: 2.1 bits; conditional E-value: 0.61 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 758 LGNAYKSLGDFRKAIEY 774 799***********986 PP == domain 19 score: 3.3 bits; conditional E-value: 0.24 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002329-T1 797 NLGIAYQSLGDFRKAIEY 814 59*************986 PP == domain 20 score: 2.3 bits; conditional E-value: 0.51 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 838 LGNAYQSLGDFRKAIEY 854 799***********986 PP == domain 21 score: 3.2 bits; conditional E-value: 0.26 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002329-T1 877 HLGIAYQSLGDFRKAIEY 894 59*************986 PP == domain 22 score: 2.3 bits; conditional E-value: 0.51 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 918 LGNAYQSLGDFRKAIEY 934 799***********986 PP == domain 23 score: 3.3 bits; conditional E-value: 0.24 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002329-T1 957 NLGIAYQSLGDFRKAIEY 974 59*************986 PP == domain 24 score: 2.3 bits; conditional E-value: 0.51 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 998 LGNAYQSLGDFRKAIEY 1014 799***********986 PP == domain 25 score: 3.3 bits; conditional E-value: 0.24 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002329-T1 1037 NLGIAYQSLGDFRKAIEY 1054 59*************986 PP == domain 26 score: 3.5 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002329-T1 1078 LGTAYRSLGDFRKAIEY 1094 89************986 PP == domain 27 score: 0.7 bits; conditional E-value: 1.7 TPR_6 5 klalsylelgdkdeAkaalqrlikk 29 +++ +y+ lg++++A++ + + ++ FUN_002329-T1 1117 NIGNAYFCLGQFENALDKFGSAVET 1141 6899999999*******99988775 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.67 6.2e+02 12 31 .. 40 59 .. 34 63 .. 0.83 2 ? 0.9 0.0 0.78 7.1e+02 14 31 .. 82 99 .. 80 102 .. 0.89 3 ? 0.9 0.0 0.76 6.9e+02 14 31 .. 122 139 .. 120 143 .. 0.89 4 ? -2.2 0.0 7 6.4e+03 14 30 .. 162 178 .. 161 181 .. 0.84 5 ? 2.1 0.0 0.33 3e+02 12 31 .. 200 219 .. 198 223 .. 0.90 6 ? -0.1 0.0 1.5 1.4e+03 12 30 .. 240 258 .. 235 262 .. 0.85 7 ? 1.0 0.0 0.7 6.3e+02 12 31 .. 280 299 .. 276 301 .. 0.86 8 ? 0.8 0.0 0.85 7.7e+02 14 31 .. 322 339 .. 320 342 .. 0.88 9 ? 1.9 0.0 0.38 3.5e+02 14 31 .. 402 419 .. 400 422 .. 0.90 10 ? 3.7 0.0 0.1 96 14 31 .. 442 459 .. 440 462 .. 0.89 11 ? -1.9 0.0 5.7 5.2e+03 11 31 .. 479 499 .. 477 501 .. 0.84 12 ? 1.9 0.0 0.38 3.5e+02 14 31 .. 522 539 .. 520 542 .. 0.90 13 ? 0.8 0.0 0.85 7.7e+02 14 31 .. 562 579 .. 560 582 .. 0.88 14 ? -0.7 0.0 2.4 2.2e+03 14 31 .. 602 619 .. 601 622 .. 0.87 15 ? -0.2 0.0 1.7 1.5e+03 14 31 .. 642 659 .. 640 662 .. 0.89 16 ? 0.5 0.0 1 9.3e+02 14 31 .. 682 699 .. 681 702 .. 0.88 17 ? 0.9 0.0 0.78 7.1e+02 14 31 .. 722 739 .. 720 742 .. 0.89 18 ? -2.3 0.0 7.8 7.1e+03 14 30 .. 762 778 .. 761 781 .. 0.83 19 ? 0.7 0.0 0.88 8e+02 12 31 .. 800 819 .. 796 822 .. 0.86 20 ? -2.2 0.0 7 6.4e+03 14 30 .. 842 858 .. 841 861 .. 0.84 21 ? 0.1 0.0 1.4 1.3e+03 12 31 .. 880 899 .. 878 902 .. 0.88 22 ? -2.2 0.0 7 6.4e+03 14 30 .. 922 938 .. 921 941 .. 0.84 23 ? 0.7 0.0 0.88 8e+02 12 31 .. 960 979 .. 956 982 .. 0.86 24 ? -2.2 0.0 7 6.4e+03 14 30 .. 1002 1018 .. 1001 1021 .. 0.84 25 ? 0.9 0.0 0.78 7.1e+02 12 31 .. 1040 1059 .. 1036 1069 .. 0.87 26 ? 1.8 0.0 0.41 3.8e+02 12 31 .. 1080 1099 .. 1075 1102 .. 0.87 27 ? 0.3 0.0 1.2 1.1e+03 14 25 .. 1122 1133 .. 1116 1151 .. 0.84 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.67 DUF2977 12 isYvlvGgledgidvdednl 31 + G ++++i+++e+ l FUN_002329-T1 40 YAFQSLGDFRKAIEYHEKHL 59 567789***********987 PP == domain 2 score: 0.9 bits; conditional E-value: 0.78 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002329-T1 82 YQSLGDFRKAIEYHEKHL 99 7889***********987 PP == domain 3 score: 0.9 bits; conditional E-value: 0.76 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002329-T1 122 YQSLGDFRKAIEYHEKHL 139 7889***********987 PP == domain 4 score: -2.2 bits; conditional E-value: 7 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002329-T1 162 YQSLGDFRKAIEYHAKH 178 7789*********9765 PP == domain 5 score: 2.1 bits; conditional E-value: 0.33 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002329-T1 200 IAYRSLGDFRKAIEYHEKDL 219 78999************877 PP == domain 6 score: -0.1 bits; conditional E-value: 1.5 DUF2977 12 isYvlvGgledgidvdedn 30 + Y G ++++i+++ + FUN_002329-T1 240 VAYQSLGDFRKAIEYHAKH 258 78999**********9766 PP == domain 7 score: 1.0 bits; conditional E-value: 0.7 DUF2977 12 isYvlvGgledgidvdednl 31 + Y G ++++i+++e+ l FUN_002329-T1 280 TAYRSLGDFRKAIEYHEKCL 299 679999**********9765 PP == domain 8 score: 0.8 bits; conditional E-value: 0.85 DUF2977 14 YvlvGgledgidvdednl 31 Y G + ++id++e+ l FUN_002329-T1 322 YQSLGDFGKAIDYHEKHL 339 7789***********987 PP == domain 9 score: 1.9 bits; conditional E-value: 0.38 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002329-T1 402 YQLLGDFRKAIEYHEKHL 419 8899***********987 PP == domain 10 score: 3.7 bits; conditional E-value: 0.1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++id++e+ l FUN_002329-T1 442 YQSLGDFRKAIDYHEKHL 459 7889***********987 PP == domain 11 score: -1.9 bits; conditional E-value: 5.7 DUF2977 11 visYvlvGgledgidvdednl 31 v Y G ++++i+++ + l FUN_002329-T1 479 VNAYQSLGVFRKAIEYHKKHL 499 5679999*********98765 PP == domain 12 score: 1.9 bits; conditional E-value: 0.38 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002329-T1 522 YQLLGDFRKAIEYHEKHL 539 8899***********987 PP == domain 13 score: 0.8 bits; conditional E-value: 0.85 DUF2977 14 YvlvGgledgidvdednl 31 Y G + ++id++e+ l FUN_002329-T1 562 YQSLGDFGKAIDYHEKHL 579 7789***********987 PP == domain 14 score: -0.7 bits; conditional E-value: 2.4 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002329-T1 602 YQSLGVFRKAIEYHEKHL 619 77899**********987 PP == domain 15 score: -0.2 bits; conditional E-value: 1.7 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+ +e+ l FUN_002329-T1 642 YQLLGDFRKAIEFHEKHL 659 8899**********9877 PP == domain 16 score: 0.5 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002329-T1 682 YRSLGDFRKAIEYHEKHL 699 7789***********987 PP == domain 17 score: 0.9 bits; conditional E-value: 0.78 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002329-T1 722 YQSLGDFRKAIEYHEKHL 739 7889***********987 PP == domain 18 score: -2.3 bits; conditional E-value: 7.8 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002329-T1 762 YKSLGDFRKAIEYHAKH 778 7789*********9765 PP == domain 19 score: 0.7 bits; conditional E-value: 0.88 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++ + l FUN_002329-T1 800 IAYQSLGDFRKAIEYHKKHL 819 8999************8765 PP == domain 20 score: -2.2 bits; conditional E-value: 7 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002329-T1 842 YQSLGDFRKAIEYHAKH 858 7789*********9765 PP == domain 21 score: 0.1 bits; conditional E-value: 1.4 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++ + l FUN_002329-T1 880 IAYQSLGDFRKAIEYHKKHL 899 78999***********8765 PP == domain 22 score: -2.2 bits; conditional E-value: 7 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002329-T1 922 YQSLGDFRKAIEYHAKH 938 7789*********9765 PP == domain 23 score: 0.7 bits; conditional E-value: 0.88 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++ + l FUN_002329-T1 960 IAYQSLGDFRKAIEYHKKHL 979 8999************8765 PP == domain 24 score: -2.2 bits; conditional E-value: 7 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002329-T1 1002 YQSLGDFRKAIEYHAKH 1018 7789*********9765 PP == domain 25 score: 0.9 bits; conditional E-value: 0.78 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++ + l FUN_002329-T1 1040 IAYQSLGDFRKAIEYHKKHL 1059 8999************8766 PP == domain 26 score: 1.8 bits; conditional E-value: 0.41 DUF2977 12 isYvlvGgledgidvdednl 31 + Y G ++++i+++e+ l FUN_002329-T1 1080 TAYRSLGDFRKAIEYHEKSL 1099 679999**********9876 PP == domain 27 score: 0.3 bits; conditional E-value: 1.2 DUF2977 14 YvlvGgledgid 25 Y G++e+++d FUN_002329-T1 1122 YFCLGQFENALD 1133 8899*******9 PP >> DBD_Tnp_Mut MuDR family transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.85 7.8e+02 9 22 .. 41 54 .. 38 61 .. 0.88 2 ? 0.5 0.0 0.73 6.7e+02 6 22 .. 78 94 .. 74 100 .. 0.88 3 ? 0.9 0.0 0.57 5.2e+02 5 23 .. 117 135 .. 113 144 .. 0.87 4 ? 2.3 0.0 0.21 1.9e+02 6 24 .. 158 176 .. 154 188 .. 0.87 5 ? 0.1 0.0 1 9.1e+02 6 23 .. 198 215 .. 196 225 .. 0.88 6 ? 2.3 0.0 0.21 1.9e+02 6 24 .. 238 256 .. 235 267 .. 0.88 7 ? -0.3 0.0 1.3 1.2e+03 6 22 .. 278 294 .. 276 299 .. 0.88 8 ? -3.0 0.0 9.2 8.4e+03 6 22 .. 398 414 .. 397 416 .. 0.82 9 ? 0.9 0.0 0.55 5e+02 6 23 .. 438 455 .. 436 462 .. 0.89 10 ? -3.0 0.0 9.2 8.4e+03 6 22 .. 518 534 .. 517 536 .. 0.82 11 ? -0.3 0.0 1.3 1.2e+03 6 22 .. 678 694 .. 676 699 .. 0.88 12 ? 0.3 0.0 0.85 7.7e+02 6 22 .. 718 734 .. 716 741 .. 0.88 13 ? 3.7 0.0 0.077 70 6 24 .. 758 776 .. 754 788 .. 0.87 14 ? 0.7 0.0 0.64 5.8e+02 6 23 .. 798 815 .. 796 822 .. 0.88 15 ? 2.3 0.0 0.21 1.9e+02 6 24 .. 838 856 .. 834 868 .. 0.87 16 ? 0.7 0.0 0.64 5.9e+02 6 23 .. 878 895 .. 876 902 .. 0.88 17 ? 2.3 0.0 0.21 1.9e+02 6 24 .. 918 936 .. 914 948 .. 0.87 18 ? 0.7 0.0 0.64 5.8e+02 6 23 .. 958 975 .. 956 982 .. 0.88 19 ? 2.3 0.0 0.21 1.9e+02 6 24 .. 998 1016 .. 994 1028 .. 0.87 20 ? 1.0 0.0 0.54 4.9e+02 6 23 .. 1038 1055 .. 1036 1069 .. 0.86 21 ? -0.3 0.0 1.3 1.2e+03 6 22 .. 1078 1094 .. 1075 1097 .. 0.87 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.85 DBD_Tnp_Mut 9 kFkdleefrkAlrk 22 F++l +frkA++ FUN_002329-T1 41 AFQSLGDFRKAIEY 54 69*********986 PP == domain 2 score: 0.5 bits; conditional E-value: 0.73 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002329-T1 78 LGNAYQSLGDFRKAIEY 94 7999**********986 PP == domain 3 score: 0.9 bits; conditional E-value: 0.57 DBD_Tnp_Mut 5 rvGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002329-T1 117 SLGNAYQSLGDFRKAIEYH 135 57999**********9865 PP == domain 4 score: 2.3 bits; conditional E-value: 0.21 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002329-T1 158 LGNAYQSLGDFRKAIEYHA 176 79999**********9987 PP == domain 5 score: 0.1 bits; conditional E-value: 1 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G + +l +frkA++ + FUN_002329-T1 198 LGIAYRSLGDFRKAIEYH 215 69999*********9865 PP == domain 6 score: 2.3 bits; conditional E-value: 0.21 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002329-T1 238 LGVAYQSLGDFRKAIEYHA 256 7999***********9987 PP == domain 7 score: -0.3 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002329-T1 278 LGTAYRSLGDFRKAIEY 294 689999********975 PP == domain 8 score: -3.0 bits; conditional E-value: 9.2 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G ++ l +frkA++ FUN_002329-T1 398 LGNAYQLLGDFRKAIEY 414 577888899*****975 PP == domain 9 score: 0.9 bits; conditional E-value: 0.55 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002329-T1 438 LGNAYQSLGDFRKAIDYH 455 69999**********865 PP == domain 10 score: -3.0 bits; conditional E-value: 9.2 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G ++ l +frkA++ FUN_002329-T1 518 LGNAYQLLGDFRKAIEY 534 577888899*****975 PP == domain 11 score: -0.3 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002329-T1 678 LGNAYRSLGDFRKAIEY 694 689999********986 PP == domain 12 score: 0.3 bits; conditional E-value: 0.85 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002329-T1 718 LGNAYQSLGDFRKAIEY 734 69999*********986 PP == domain 13 score: 3.7 bits; conditional E-value: 0.077 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +k+l +frkA++ +a FUN_002329-T1 758 LGNAYKSLGDFRKAIEYHA 776 7999***********9987 PP == domain 14 score: 0.7 bits; conditional E-value: 0.64 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002329-T1 798 LGIAYQSLGDFRKAIEYH 815 7999**********9865 PP == domain 15 score: 2.3 bits; conditional E-value: 0.21 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002329-T1 838 LGNAYQSLGDFRKAIEYHA 856 79999**********9987 PP == domain 16 score: 0.7 bits; conditional E-value: 0.64 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002329-T1 878 LGIAYQSLGDFRKAIEYH 895 6999**********9865 PP == domain 17 score: 2.3 bits; conditional E-value: 0.21 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002329-T1 918 LGNAYQSLGDFRKAIEYHA 936 79999**********9987 PP == domain 18 score: 0.7 bits; conditional E-value: 0.64 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002329-T1 958 LGIAYQSLGDFRKAIEYH 975 7999**********9865 PP == domain 19 score: 2.3 bits; conditional E-value: 0.21 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002329-T1 998 LGNAYQSLGDFRKAIEYHA 1016 79999**********9987 PP == domain 20 score: 1.0 bits; conditional E-value: 0.54 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002329-T1 1038 LGIAYQSLGDFRKAIEYH 1055 7999**********9865 PP == domain 21 score: -0.3 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002329-T1 1078 LGTAYRSLGDFRKAIEY 1094 68999*********985 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 4 3.7e+03 3 20 .. 74 91 .. 73 92 .. 0.87 2 ? -1.4 0.0 9 8.3e+03 6 20 .. 117 131 .. 114 132 .. 0.87 3 ? -0.8 0.0 5.7 5.2e+03 4 20 .. 155 171 .. 153 172 .. 0.86 4 ? 0.6 0.0 2 1.8e+03 2 20 .. 193 211 .. 192 212 .. 0.90 5 ? 2.8 0.0 0.38 3.5e+02 2 20 .. 233 251 .. 232 253 .. 0.90 6 ? 0.5 0.0 2.1 1.9e+03 3 20 .. 274 291 .. 273 292 .. 0.89 7 ? 1.8 0.0 0.83 7.6e+02 3 20 .. 314 331 .. 312 332 .. 0.89 8 ? 2.1 0.0 0.63 5.7e+02 4 20 .. 395 411 .. 393 413 .. 0.86 9 ? 0.8 0.0 1.7 1.5e+03 2 20 .. 433 451 .. 432 452 .. 0.89 10 ? 2.1 0.0 0.63 5.7e+02 4 20 .. 515 531 .. 513 533 .. 0.86 11 ? -0.9 0.0 6.1 5.6e+03 5 20 .. 556 571 .. 554 572 .. 0.85 12 ? 2.3 0.0 0.57 5.2e+02 4 20 .. 635 651 .. 633 654 .. 0.86 13 ? -1.0 0.0 6.5 5.9e+03 5 20 .. 716 731 .. 714 732 .. 0.85 14 ? 3.6 0.0 0.22 2e+02 2 20 .. 793 811 .. 792 813 .. 0.91 15 ? -0.8 0.0 5.7 5.2e+03 4 20 .. 835 851 .. 833 852 .. 0.86 16 ? 1.8 0.0 0.81 7.4e+02 2 20 .. 873 891 .. 872 893 .. 0.90 17 ? -0.8 0.0 5.7 5.2e+03 4 20 .. 915 931 .. 913 932 .. 0.86 18 ? 3.6 0.0 0.22 2e+02 2 20 .. 953 971 .. 952 973 .. 0.91 19 ? -0.8 0.0 5.7 5.2e+03 4 20 .. 995 1011 .. 993 1012 .. 0.86 20 ? 3.6 0.0 0.22 2e+02 2 20 .. 1033 1051 .. 1032 1053 .. 0.91 21 ? 0.6 0.0 2 1.8e+03 3 20 .. 1074 1091 .. 1072 1092 .. 0.89 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 4 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a++ lGd+ A FUN_002329-T1 74 AYRSLGNAYQSLGDFRKA 91 56789*********9877 PP == domain 2 score: -1.4 bits; conditional E-value: 9 TPR_4 6 aLArallalGdldeA 20 L+ a++ lGd+ A FUN_002329-T1 117 SLGNAYQSLGDFRKA 131 6999*******9877 PP == domain 3 score: -0.8 bits; conditional E-value: 5.7 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002329-T1 155 YGSLGNAYQSLGDFRKA 171 5679*********9877 PP == domain 4 score: 0.6 bits; conditional E-value: 2 TPR_4 2 rallaLArallalGdldeA 20 ra+ L+ a+ lGd+ A FUN_002329-T1 193 RAYGSLGIAYRSLGDFRKA 211 78999**********9877 PP == domain 5 score: 2.8 bits; conditional E-value: 0.38 TPR_4 2 rallaLArallalGdldeA 20 +a+ +L+ a++ lGd+ A FUN_002329-T1 233 VAYGNLGVAYQSLGDFRKA 251 6899***********9887 PP == domain 6 score: 0.5 bits; conditional E-value: 2.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002329-T1 274 AYGNLGTAYRSLGDFRKA 291 6789**********9877 PP == domain 7 score: 1.8 bits; conditional E-value: 0.83 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002329-T1 314 AYGNLGNAYQSLGDFGKA 331 789***********9877 PP == domain 8 score: 2.1 bits; conditional E-value: 0.63 TPR_4 4 llaLArallalGdldeA 20 + L+ a+++lGd+ A FUN_002329-T1 395 YGSLGNAYQLLGDFRKA 411 5679*********9887 PP == domain 9 score: 0.8 bits; conditional E-value: 1.7 TPR_4 2 rallaLArallalGdldeA 20 ra+ L+ a++ lGd+ A FUN_002329-T1 433 RAYGSLGNAYQSLGDFRKA 451 78999**********9877 PP == domain 10 score: 2.1 bits; conditional E-value: 0.63 TPR_4 4 llaLArallalGdldeA 20 + L+ a+++lGd+ A FUN_002329-T1 515 YGSLGNAYQLLGDFRKA 531 5679*********9887 PP == domain 11 score: -0.9 bits; conditional E-value: 6.1 TPR_4 5 laLArallalGdldeA 20 L+ a++ lGd+ A FUN_002329-T1 556 GSLGNAYQSLGDFGKA 571 6799********9877 PP == domain 12 score: 2.3 bits; conditional E-value: 0.57 TPR_4 4 llaLArallalGdldeA 20 + L+ a+++lGd+ A FUN_002329-T1 635 YGSLGNAYQLLGDFRKA 651 5679*********9987 PP == domain 13 score: -1.0 bits; conditional E-value: 6.5 TPR_4 5 laLArallalGdldeA 20 L+ a++ lGd+ A FUN_002329-T1 716 GSLGNAYQSLGDFRKA 731 6799********9877 PP == domain 14 score: 3.6 bits; conditional E-value: 0.22 TPR_4 2 rallaLArallalGdldeA 20 ra+ +L+ a++ lGd+ A FUN_002329-T1 793 RAYGNLGIAYQSLGDFRKA 811 8999***********9887 PP == domain 15 score: -0.8 bits; conditional E-value: 5.7 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002329-T1 835 YGSLGNAYQSLGDFRKA 851 5679*********9877 PP == domain 16 score: 1.8 bits; conditional E-value: 0.81 TPR_4 2 rallaLArallalGdldeA 20 ra+ L+ a++ lGd+ A FUN_002329-T1 873 RAYGHLGIAYQSLGDFRKA 891 78999**********9887 PP == domain 17 score: -0.8 bits; conditional E-value: 5.7 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002329-T1 915 YGSLGNAYQSLGDFRKA 931 5679*********9877 PP == domain 18 score: 3.6 bits; conditional E-value: 0.22 TPR_4 2 rallaLArallalGdldeA 20 ra+ +L+ a++ lGd+ A FUN_002329-T1 953 RAYGNLGIAYQSLGDFRKA 971 8999***********9887 PP == domain 19 score: -0.8 bits; conditional E-value: 5.7 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002329-T1 995 YGSLGNAYQSLGDFRKA 1011 5679*********9877 PP == domain 20 score: 3.6 bits; conditional E-value: 0.22 TPR_4 2 rallaLArallalGdldeA 20 ra+ +L+ a++ lGd+ A FUN_002329-T1 1033 RAYGNLGIAYQSLGDFRKA 1051 8999***********9887 PP == domain 21 score: 0.6 bits; conditional E-value: 2 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002329-T1 1074 AYGNLGTAYRSLGDFRKA 1091 6789**********9877 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.0 0.6 0.0014 1.2 38 176 .. 35 173 .. 27 185 .. 0.83 2 ? 2.9 0.0 0.096 87 38 140 .. 115 217 .. 111 222 .. 0.90 3 ? 1.3 0.1 0.29 2.6e+02 42 180 .. 159 297 .. 152 308 .. 0.82 4 ! 6.2 0.0 0.0095 8.6 42 180 .. 279 417 .. 268 424 .. 0.77 5 ? 4.7 0.0 0.027 25 42 145 .. 319 422 .. 311 457 .. 0.75 6 ! 9.3 0.0 0.0011 0.98 42 179 .. 439 576 .. 427 585 .. 0.86 7 ! 7.3 0.0 0.0045 4.1 39 144 .. 516 621 .. 510 654 .. 0.82 8 ! 10.3 0.0 0.00052 0.47 38 140 .. 635 737 .. 631 741 .. 0.94 9 ! 7.8 0.1 0.003 2.8 38 143 .. 755 860 .. 751 900 .. 0.86 10 ? 3.4 0.0 0.066 60 40 140 .. 917 1017 .. 911 1024 .. 0.91 11 ! 6.5 0.0 0.0079 7.2 44 147 .. 1041 1144 .. 1032 1154 .. 0.90 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0014 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y++ A a++ ++++A e ++k e+ +++ + +nay ++y++ d +A+e ek ei +e g ++ + ++++ y++ +d++ FUN_002329-T1 35 YQNLAYAFQSLGDFRKAIEYHEKHLEIAIEAGHRVGEGNAYRSLGNAYQSLgDFRKAIEYHEKHLEIAIEVGDRVGEGNVYGSLGNAYQSL-GDFR 129 6667888888889999999999999999999999999999999999999876999999999999999999999999999999999999977.9999 PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAie 176 kAie+ e+ ++ + + +++ + + + +l+++ kAie FUN_002329-T1 130 KAIEYHEKHLEIAIEVSHRVGEGNAYGSLGNAYQSLGDFRKAIE 173 99999999888766666666666666666666666666666666 PP == domain 2 score: 2.9 bits; conditional E-value: 0.096 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+ ++++A e ++k e+ +++ + +nay ++y++ d +A+e k ei ++ g ++ + +++ y++ +d++ FUN_002329-T1 115 YGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVSHRVGEGNAYGSLGNAYQSLgDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGSLGIAYRSL-GDFR 209 5566899999999***********************************9977999*****************9999999999999999977.9*** PP SNAP 133 kAieaYeq 140 kAie+ e+ FUN_002329-T1 210 KAIEYHEK 217 **999987 PP == domain 3 score: 1.3 bits; conditional E-value: 0.29 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay+ ++++A e ++k e+ k++ + ++ay +y++ d +A+e ek ei +e g + + +++ y++ +d++kAie FUN_002329-T1 159 GNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGSLGIAYRSLgDFRKAIEYHEKDLEIAIEVGYRVGEGVAYGNLGVAYQSL-GDFRKAIE 253 788888888889999999999999999999999999999888888876888999999999999999998888888889999999876.99999999 PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + ++ ++ + + + + ++ ++ + +l+++ kAie ek FUN_002329-T1 254 YHAKHLEIAIKIGHQVGEEGAYGNLGTAYRSLGDFRKAIEYHEK 297 99999998888888888888888888888888888888888886 PP == domain 4 score: 6.2 bits; conditional E-value: 0.0095 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 ++ay+ ++++A e ++k+ e+ ++++ + ++ay + ++y++ d +A++ ek ei +e g ++ + ++++ y++ + ++kAie FUN_002329-T1 279 GTAYRSLGDFRKAIEYHEKCLEIAKEVSGRVGEGSAYGNLGNAYQSLgDFGKAIDYHEKHLEIAIEVGDRVGEGNAYGSLGNAYQSL-GVFRKAIE 373 567888888888888888888888888888888888888888888765778888888888888888888888888888888888866.88888888 PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + ++ ++ + + +++ + + + l+++ kAie ek FUN_002329-T1 374 YHKKHLEIAIEVGHRVGEGNAYGSLGNAYQLLGDFRKAIEYHEK 417 88887777777777777777777777777777777777776665 PP == domain 5 score: 4.7 bits; conditional E-value: 0.027 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay+ ++ +A + ++k e+ +++++ +nay ++y++ +A+e +k ei +e g ++ + ++++ y+ +d++kAie FUN_002329-T1 319 GNAYQSLGDFGKAIDYHEKHLEIAIEVGDRVGEGNAYGSLGNAYQSLgVFRKAIEYHKKHLEIAIEVGHRVGEGNAYGSLGNAYQLL-GDFRKAIE 413 788888888999999999999999999999999999999999999875678999999999999999999999999999999999866.99999999 PP SNAP 137 aYeqAadly 145 + e+ ++ FUN_002329-T1 414 YHEKHLEIA 422 988876654 PP == domain 6 score: 9.3 bits; conditional E-value: 0.0011 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay+ ++++A + ++k e+ +++++ e +nay ++y++ +A+e +k ei +e g ++ + ++++ y+ +d++kAie FUN_002329-T1 439 GNAYQSLGDFRKAIDYHEKHLEIAIEVGDRVEEGNAYGSLVNAYQSLgVFRKAIEYHKKHLEIAIEVGHRVGEGNAYGSLGNAYQLL-GDFRKAIE 533 79999999************************************9985788*********************************977.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiye 179 + e+ ++ + + k++ + + + +l+++ kAi+ e FUN_002329-T1 534 YHEKHLEIAIEVGDRVGEGKAYGSLGNAYQSLGDFGKAIDYHE 576 **99888776666666666666666666666666666666655 PP == domain 7 score: 7.3 bits; conditional E-value: 0.0045 SNAP 39 kqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlek 133 + +nay+l ++++A e ++k e+ +++++ ++ay ++y++ d +A++ ek ei +e g + ++ + ++++ y++ + ++k FUN_002329-T1 516 GSLGNAYQLLGDFRKAIEYHEKHLEIAIEVGDRVGEGKAYGSLGNAYQSLgDFGKAIDYHEKHLEIAIEVGDRVEEGNAYGSLGNAYQSL-GVFRK 610 556899999999999999999999999999999999999999999999976899999999999999999999999999999999999977.99999 PP SNAP 134 AieaYeqAadl 144 Aie+ e+ ++ FUN_002329-T1 611 AIEYHEKHLEI 621 99999987665 PP == domain 8 score: 10.3 bits; conditional E-value: 0.00052 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+l ++++A e ++k e+ +++++ ++ay ++y++ d +A+e ek ei +e g +k + ++++ y++ +d++ FUN_002329-T1 635 YGSLGNAYQLLGDFRKAIEFHEKHLEIAIEVGDRVGEGKAYGSLGNAYRSLgDFRKAIEYHEKHLEIAIEVGDRVGEGKAYGSLGNAYQSL-GDFR 729 556689*******************************************98799**********************************987.**** PP SNAP 133 kAieaYeq 140 kAie+ e+ FUN_002329-T1 730 KAIEYHEK 737 ****9987 PP == domain 9 score: 7.8 bits; conditional E-value: 0.003 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nayk ++++A e ++k e+ k++ + ++ay + +y++ d +A+e +k ei +e+g ++ + ++++ y++ +d++ FUN_002329-T1 755 YGSLGNAYKSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLgDFRKAIEYHKKHLEIAIEAGHRVGEGNAYGSLGNAYQSL-GDFR 849 556689******************************************997799**********************************987.**** PP SNAP 133 kAieaYeqAad 143 kAie+ ++ + FUN_002329-T1 850 KAIEYHAKHLE 860 ****9887666 PP == domain 10 score: 3.4 bits; conditional E-value: 0.066 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 + +nay+ ++++A e ++k e+ k++ + ++ay + +y++ d +A+e +k ei +e g ++ + ++++ y++ +d++ FUN_002329-T1 917 SLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLgDFRKAIEYHKKHLEIAIEVGHRVGEGNAYGSLGNAYQSL-GDFR 1009 557999999999*****************************999999977999*******************99************987.**** PP SNAP 133 kAieaYeq 140 kAie+ ++ FUN_002329-T1 1010 KAIEYHAK 1017 ***98776 PP == domain 11 score: 6.5 bits; conditional E-value: 0.0079 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 ay+ ++++A e + k e+ +++ + +nay + ++y++ d +A+e ek+ ei +e g + + +i++ y +++e+A++ FUN_002329-T1 1041 AYQSLGDFRKAIEYHKKHLEIAIEVDYRVGEGNAYGNLGTAYRSLgDFRKAIEYHEKSLEIAIEVGHRAGEGIAHHNIGNAYFCL-GQFENALD 1133 5666677889999999999999999999999***********998799*******************999999*********977.******** PP SNAP 137 aYeqAadlyeq 147 ++ A + +++ FUN_002329-T1 1134 KFGSAVETFNT 1144 *******9975 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 0.6 0.028 26 3 58 .. 38 99 .. 37 104 .. 0.81 2 ? 1.5 0.0 0.65 5.9e+02 3 19 .. 118 134 .. 117 140 .. 0.91 3 ! 9.9 0.1 0.0016 1.4 3 53 .. 158 214 .. 157 222 .. 0.88 4 ? -0.6 0.0 3 2.7e+03 3 19 .. 238 254 .. 237 260 .. 0.83 5 ? 5.5 0.1 0.037 33 3 58 .. 278 339 .. 277 343 .. 0.81 6 ? 0.8 0.1 1.1 1e+03 10 56 .. 358 417 .. 350 424 .. 0.58 7 ? 3.0 0.2 0.22 2e+02 4 56 .. 399 457 .. 396 464 .. 0.64 8 ? -0.7 0.0 3.3 3e+03 33 53 .. 514 534 .. 497 543 .. 0.65 9 ? 3.0 0.1 0.22 2e+02 4 58 .. 519 579 .. 517 584 .. 0.73 10 ? 0.5 0.1 1.4 1.3e+03 4 53 .. 592 654 .. 589 664 .. 0.60 11 ? 4.9 0.1 0.058 53 18 58 .. 657 699 .. 637 704 .. 0.67 12 ? 5.7 0.1 0.033 30 3 57 .. 678 738 .. 677 744 .. 0.76 13 ? 4.3 0.1 0.09 82 3 53 .. 718 774 .. 710 783 .. 0.74 14 ? 7.3 0.1 0.01 9.6 3 59 .. 758 820 .. 757 825 .. 0.84 15 ? 6.8 0.0 0.015 13 3 58 .. 838 899 .. 837 903 .. 0.84 16 ! 8.3 0.1 0.0051 4.6 3 58 .. 918 979 .. 917 984 .. 0.86 17 ! 8.3 0.1 0.005 4.6 3 58 .. 998 1059 .. 997 1065 .. 0.86 18 ! 8.6 0.0 0.0039 3.6 3 57 .. 1038 1098 .. 1037 1105 .. 0.85 19 ? 6.1 0.0 0.024 22 3 54 .. 1078 1135 .. 1076 1144 .. 0.79 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.028 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 la a+ +gd++ A+++ le a++++ A++ lG a+ +g++ +A+++ ++ l FUN_002329-T1 38 LAYAFQSLGDFRKAIEYhekhLEIAIEAGhrVGEGNAYRSLGNAYQSLGDFRKAIEYHEKHL 99 78899999999999875444499999999997789999999999999999999998866666 PP == domain 2 score: 1.5 bits; conditional E-value: 0.65 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002329-T1 118 LGNAYQSLGDFRKAIEY 134 799***********986 PP == domain 3 score: 9.9 bits; conditional E-value: 0.0016 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ le a++ + +A+ lG a+ +g++ +A+++ FUN_002329-T1 158 LGNAYQSLGDFRKAIEYhakhLEIAIKVGhrVGEGRAYGSLGIAYRSLGDFRKAIEY 214 799***********7644444**********7799*******************976 PP == domain 4 score: -0.6 bits; conditional E-value: 3 TPR_16 3 laraalaagdyddAaaa 19 l+ a+ +gd++ A+++ FUN_002329-T1 238 LGVAYQSLGDFRKAIEY 254 67789999999999875 PP == domain 5 score: 5.5 bits; conditional E-value: 0.037 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd++ A+++ e l+ A+ +lG a+ +g++ +A+++ ++ l FUN_002329-T1 278 LGTAYRSLGDFRKAIEYHEKCLEIAkevsgrVGEGSAYGNLGNAYQSLGDFGKAIDYHEKHL 339 79999999999999998887777777778886688999999999999999999998866655 PP == domain 6 score: 0.8 bits; conditional E-value: 1.1 TPR_16 10 agdyddAaaaleaalrrn.............PeaaaAllglGlallrqgrlaeAaaayra 56 +g+ +++ ++ a++++ A+ lG a+ +g++ +A+++ ++ FUN_002329-T1 358 LGNAYQSLGVFRKAIEYHkkhleiaievghrVGEGNAYGSLGNAYQLLGDFRKAIEYHEK 417 455555555555555555444444444446655667777788888788888777776555 PP == domain 7 score: 3.0 bits; conditional E-value: 0.22 TPR_16 4 araalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayra 56 ++a+ +gd++ A+++ le a++ + +A+ lG a+ +g++ +A+++ ++ FUN_002329-T1 399 GNAYQLLGDFRKAIEYhekhLEIAIEVGdrVGEGRAYGSLGNAYQSLGDFRKAIDYHEK 457 55555566666666533333677777777755777888888888888888888776555 PP == domain 8 score: -0.7 bits; conditional E-value: 3.3 TPR_16 33 AllglGlallrqgrlaeAaaa 53 A+ lG a+ +g++ +A+++ FUN_002329-T1 514 AYGSLGNAYQLLGDFRKAIEY 534 666666666666666666665 PP == domain 9 score: 3.0 bits; conditional E-value: 0.22 TPR_16 4 araalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 ++a+ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ ++ l FUN_002329-T1 519 GNAYQLLGDFRKAIEYhekhLEIAIEVGdrVGEGKAYGSLGNAYQSLGDFGKAIDYHEKHL 579 6666667777777654333378888888886678899999999999999999998866665 PP == domain 10 score: 0.5 bits; conditional E-value: 1.4 TPR_16 4 araalaagdyddAaaaleaalrrn.............PeaaaAllglGlallrqgrlaeAaaa 53 ++a+ +g+ +++ ++ a++++ A+ lG a+ +g++ +A+++ FUN_002329-T1 592 GNAYGSLGNAYQSLGVFRKAIEYHekhleiaievghrVGEGNAYGSLGNAYQLLGDFRKAIEF 654 666666666666666666666666444444444446644566677777777777777666665 PP == domain 11 score: 4.9 bits; conditional E-value: 0.058 TPR_16 18 aaleaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 + le a++ + A+ lG a+ +g++ +A+++ ++ l FUN_002329-T1 657 KHLEIAIEVGdrVGEGKAYGSLGNAYRSLGDFRKAIEYHEKHL 699 4677777777775567788888888888888888888766655 PP == domain 12 score: 5.7 bits; conditional E-value: 0.033 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraa 57 l++a++ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ ++ FUN_002329-T1 678 LGNAYRSLGDFRKAIEYhekhLEIAIEVGdrVGEGKAYGSLGNAYQSLGDFRKAIEYHEKH 738 7899999999999987544448888888888667888888888888888888888876655 PP == domain 13 score: 4.3 bits; conditional E-value: 0.09 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ FUN_002329-T1 718 LGNAYQSLGDFRKAIEYhekhLEIAIEVGhrVGEGNAYGSLGNAYKSLGDFRKAIEY 774 689999999999998753333777777778855777888888888888888888776 PP == domain 14 score: 7.3 bits; conditional E-value: 0.01 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ le a++ + +A+ +lG a+ +g++ +A+++ ++ l+ FUN_002329-T1 758 LGNAYKSLGDFRKAIEYhakhLEIAIKVGhrVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHLE 820 7999999999999976444449*********7799********************99777665 PP == domain 15 score: 6.8 bits; conditional E-value: 0.015 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ le a++ + +A+ lG a+ +g++ +A+++ ++ l FUN_002329-T1 838 LGNAYQSLGDFRKAIEYhakhLEIAIKVGhrVGEGRAYGHLGIAYQSLGDFRKAIEYHKKHL 899 799***********764444499999999**77999***************99999866665 PP == domain 16 score: 8.3 bits; conditional E-value: 0.0051 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ le a++ + +A+ +lG a+ +g++ +A+++ ++ l FUN_002329-T1 918 LGNAYQSLGDFRKAIEYhakhLEIAIKVGhrVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHL 979 799***********7644444**********7799********************9876666 PP == domain 17 score: 8.3 bits; conditional E-value: 0.005 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ le a++ + +A+ +lG a+ +g++ +A+++ ++ l FUN_002329-T1 998 LGNAYQSLGDFRKAIEYhakhLEIAIKVGhrVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHL 1059 799***********7644444**********7799********************9877666 PP == domain 18 score: 8.6 bits; conditional E-value: 0.0039 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraa 57 l+ a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ FUN_002329-T1 1038 LGIAYQSLGDFRKAIEYhkkhLEIAIEVDyrVGEGNAYGNLGTAYRSLGDFRKAIEYHEKS 1098 78999999******9755555999**9999977899*******************886655 PP == domain 19 score: 6.1 bits; conditional E-value: 0.024 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaay 54 l++a++ +gd++ A+++ le a++ + A+ + G a++ +g ++ A++ + FUN_002329-T1 1078 LGTAYRSLGDFRKAIEYheksLEIAIEVGhrAGEGIAHHNIGNAYFCLGQFENALDKF 1135 799***********98633337777777799889999999999999999999999555 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 5.5 5e+03 9 24 .. 41 56 .. 35 57 .. 0.79 2 ? 3.2 0.0 0.2 1.9e+02 3 24 .. 75 96 .. 74 97 .. 0.90 3 ? 4.0 0.0 0.11 97 3 24 .. 115 136 .. 114 137 .. 0.91 4 ? 2.7 0.0 0.28 2.5e+02 3 23 .. 155 175 .. 154 177 .. 0.90 5 ? 2.8 0.0 0.27 2.5e+02 2 24 .. 194 216 .. 193 217 .. 0.88 6 ? -0.9 0.0 3.9 3.5e+03 2 23 .. 234 255 .. 233 257 .. 0.80 7 ? 3.1 0.0 0.22 2e+02 3 26 .. 275 298 .. 274 301 .. 0.84 8 ? 0.5 0.0 1.4 1.3e+03 2 24 .. 314 336 .. 313 337 .. 0.87 9 ? 0.4 0.0 1.6 1.5e+03 3 24 .. 355 376 .. 353 377 .. 0.69 10 ? 2.2 0.0 0.42 3.9e+02 3 24 .. 395 416 .. 394 417 .. 0.90 11 ? 3.7 0.0 0.14 1.3e+02 2 24 .. 434 456 .. 433 457 .. 0.91 12 ? 4.1 0.0 0.099 90 3 25 .. 475 497 .. 474 497 .. 0.92 13 ? 2.2 0.0 0.42 3.9e+02 3 24 .. 515 536 .. 514 537 .. 0.90 14 ? 1.9 0.0 0.52 4.8e+02 2 24 .. 554 576 .. 553 577 .. 0.90 15 ? 0.2 0.0 1.8 1.6e+03 3 23 .. 595 615 .. 593 617 .. 0.66 16 ? 2.3 0.0 0.38 3.5e+02 3 24 .. 635 656 .. 634 657 .. 0.90 17 ? 5.5 0.0 0.035 32 2 24 .. 674 696 .. 673 697 .. 0.91 18 ? 4.2 0.0 0.095 87 2 24 .. 714 736 .. 713 737 .. 0.91 19 ? 4.3 0.0 0.085 78 3 23 .. 755 775 .. 754 777 .. 0.90 20 ? 0.3 0.0 1.7 1.5e+03 5 25 .. 797 817 .. 793 817 .. 0.80 21 ? 2.7 0.0 0.28 2.5e+02 3 23 .. 835 855 .. 834 857 .. 0.90 22 ? -0.1 0.0 2.3 2.1e+03 9 25 .. 881 897 .. 874 897 .. 0.81 23 ? 2.7 0.0 0.28 2.5e+02 3 23 .. 915 935 .. 914 937 .. 0.90 24 ? 0.3 0.0 1.7 1.5e+03 5 25 .. 957 977 .. 953 977 .. 0.80 25 ? 2.7 0.0 0.28 2.5e+02 3 23 .. 995 1015 .. 994 1017 .. 0.90 26 ? 0.3 0.0 1.7 1.5e+03 5 25 .. 1037 1057 .. 1033 1057 .. 0.80 27 ? 2.6 0.0 0.3 2.7e+02 3 25 .. 1075 1097 .. 1074 1101 .. 0.85 28 ? -0.6 0.0 3.3 3e+03 8 23 .. 1120 1135 .. 1118 1139 .. 0.89 29 ? -0.2 0.0 2.4 2.2e+03 2 20 .. 1166 1184 .. 1165 1185 .. 0.89 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 5.5 PPR 9 gycknGkleeAlelfk 24 ++ + G++++A+e+++ FUN_002329-T1 41 AFQSLGDFRKAIEYHE 56 66678********987 PP == domain 2 score: 3.2 bits; conditional E-value: 0.2 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002329-T1 75 YRSLGNAYQSLGDFRKAIEYHE 96 88999**************987 PP == domain 3 score: 4.0 bits; conditional E-value: 0.11 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002329-T1 115 YGSLGNAYQSLGDFRKAIEYHE 136 99999**************987 PP == domain 4 score: 2.7 bits; conditional E-value: 0.28 PPR 3 ynslIsgycknGkleeAlelf 23 y sl ++y + G++++A+e++ FUN_002329-T1 155 YGSLGNAYQSLGDFRKAIEYH 175 99999*************975 PP == domain 5 score: 2.8 bits; conditional E-value: 0.27 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl +y + G++++A+e+++ FUN_002329-T1 194 AYGSLGIAYRSLGDFRKAIEYHE 216 5888999*************987 PP == domain 6 score: -0.9 bits; conditional E-value: 3.9 PPR 2 tynslIsgycknGkleeAlelf 23 +y l +y + G++++A+e++ FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEYH 255 566667789999******9975 PP == domain 7 score: 3.1 bits; conditional E-value: 0.22 PPR 3 ynslIsgycknGkleeAlelfkeM 26 y l +y + G++++A+e++++ FUN_002329-T1 275 YGNLGTAYRSLGDFRKAIEYHEKC 298 6677789************99875 PP == domain 8 score: 0.5 bits; conditional E-value: 1.4 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++ +A+++++ FUN_002329-T1 314 AYGNLGNAYQSLGDFGKAIDYHE 336 6888899************9887 PP == domain 9 score: 0.4 bits; conditional E-value: 1.6 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G +++A+e++k FUN_002329-T1 355 YGSLGNAYQSLGVFRKAIEYHK 376 6777777777777777777766 PP == domain 10 score: 2.2 bits; conditional E-value: 0.42 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y G++++A+e+++ FUN_002329-T1 395 YGSLGNAYQLLGDFRKAIEYHE 416 89999**************987 PP == domain 11 score: 3.7 bits; conditional E-value: 0.14 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+++++ FUN_002329-T1 434 AYGSLGNAYQSLGDFRKAIDYHE 456 69999**************9987 PP == domain 12 score: 4.1 bits; conditional E-value: 0.099 PPR 3 ynslIsgycknGkleeAlelfke 25 y sl+++y + G +++A+e++k+ FUN_002329-T1 475 YGSLVNAYQSLGVFRKAIEYHKK 497 99*****************9875 PP == domain 13 score: 2.2 bits; conditional E-value: 0.42 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y G++++A+e+++ FUN_002329-T1 515 YGSLGNAYQLLGDFRKAIEYHE 536 89999**************987 PP == domain 14 score: 1.9 bits; conditional E-value: 0.52 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++ +A+++++ FUN_002329-T1 554 AYGSLGNAYQSLGDFGKAIDYHE 576 599999*************9987 PP == domain 15 score: 0.2 bits; conditional E-value: 1.8 PPR 3 ynslIsgycknGkleeAlelf 23 y sl ++y + G +++A+e++ FUN_002329-T1 595 YGSLGNAYQSLGVFRKAIEYH 615 667777777777777777766 PP == domain 16 score: 2.3 bits; conditional E-value: 0.38 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y G++++A+e+++ FUN_002329-T1 635 YGSLGNAYQLLGDFRKAIEFHE 656 89999**************987 PP == domain 17 score: 5.5 bits; conditional E-value: 0.035 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002329-T1 674 AYGSLGNAYRSLGDFRKAIEYHE 696 59999***************987 PP == domain 18 score: 4.2 bits; conditional E-value: 0.095 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002329-T1 714 AYGSLGNAYQSLGDFRKAIEYHE 736 599999**************987 PP == domain 19 score: 4.3 bits; conditional E-value: 0.085 PPR 3 ynslIsgycknGkleeAlelf 23 y sl ++y + G++++A+e++ FUN_002329-T1 755 YGSLGNAYKSLGDFRKAIEYH 775 99999*************975 PP == domain 20 score: 0.3 bits; conditional E-value: 1.7 PPR 5 slIsgycknGkleeAlelfke 25 l +y + G++++A+e++k+ FUN_002329-T1 797 NLGIAYQSLGDFRKAIEYHKK 817 555688999********9875 PP == domain 21 score: 2.7 bits; conditional E-value: 0.28 PPR 3 ynslIsgycknGkleeAlelf 23 y sl ++y + G++++A+e++ FUN_002329-T1 835 YGSLGNAYQSLGDFRKAIEYH 855 99999*************975 PP == domain 22 score: -0.1 bits; conditional E-value: 2.3 PPR 9 gycknGkleeAlelfke 25 +y + G++++A+e++k+ FUN_002329-T1 881 AYQSLGDFRKAIEYHKK 897 78899********9875 PP == domain 23 score: 2.7 bits; conditional E-value: 0.28 PPR 3 ynslIsgycknGkleeAlelf 23 y sl ++y + G++++A+e++ FUN_002329-T1 915 YGSLGNAYQSLGDFRKAIEYH 935 99999*************975 PP == domain 24 score: 0.3 bits; conditional E-value: 1.7 PPR 5 slIsgycknGkleeAlelfke 25 l +y + G++++A+e++k+ FUN_002329-T1 957 NLGIAYQSLGDFRKAIEYHKK 977 555688999********9875 PP == domain 25 score: 2.7 bits; conditional E-value: 0.28 PPR 3 ynslIsgycknGkleeAlelf 23 y sl ++y + G++++A+e++ FUN_002329-T1 995 YGSLGNAYQSLGDFRKAIEYH 1015 99999*************975 PP == domain 26 score: 0.3 bits; conditional E-value: 1.7 PPR 5 slIsgycknGkleeAlelfke 25 l +y + G++++A+e++k+ FUN_002329-T1 1037 NLGIAYQSLGDFRKAIEYHKK 1057 555688999********9875 PP == domain 27 score: 2.6 bits; conditional E-value: 0.3 PPR 3 ynslIsgycknGkleeAlelfke 25 y l +y + G++++A+e++++ FUN_002329-T1 1075 YGNLGTAYRSLGDFRKAIEYHEK 1097 6677789************9987 PP == domain 28 score: -0.6 bits; conditional E-value: 3.3 PPR 8 sgycknGkleeAlelf 23 ++y G++e Al+ f FUN_002329-T1 1120 NAYFCLGQFENALDKF 1135 79**********9866 PP == domain 29 score: -0.2 bits; conditional E-value: 2.4 PPR 2 tynslIsgycknGkleeAl 20 +y ++ +++ + Gk++eAl FUN_002329-T1 1166 SYCAMWRSLLRIGKIDEAL 1184 788899999*********7 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 0.064 58 37 73 .. 33 69 .. 10 70 .. 0.89 2 ? 2.2 0.0 0.2 1.8e+02 38 67 .. 74 103 .. 72 109 .. 0.85 3 ? 1.9 0.0 0.24 2.2e+02 40 72 .. 116 148 .. 113 150 .. 0.86 4 ? 4.2 0.0 0.049 45 38 74 .. 154 190 .. 151 220 .. 0.82 5 ? -1.8 0.0 3.4 3.1e+03 38 65 .. 194 221 .. 191 230 .. 0.79 6 ? 2.2 0.0 0.2 1.9e+02 38 72 .. 234 268 .. 232 270 .. 0.90 7 ? 2.4 0.0 0.17 1.6e+02 38 64 .. 274 300 .. 272 309 .. 0.88 8 ? 1.3 0.1 0.38 3.5e+02 33 67 .. 309 343 .. 293 349 .. 0.79 9 ? -0.7 0.0 1.5 1.4e+03 38 72 .. 354 388 .. 352 390 .. 0.89 10 ? 0.0 0.0 0.9 8.2e+02 38 68 .. 394 424 .. 392 430 .. 0.84 11 ? 1.3 0.0 0.38 3.5e+02 37 70 .. 433 466 .. 431 472 .. 0.85 12 ? -1.3 0.0 2.3 2.1e+03 37 72 .. 473 508 .. 456 510 .. 0.84 13 ? 0.1 0.0 0.88 8e+02 38 68 .. 514 544 .. 511 550 .. 0.84 14 ? -0.3 0.0 1.1 1e+03 38 70 .. 554 586 .. 552 592 .. 0.84 15 ? 0.7 0.0 0.56 5.1e+02 36 72 .. 592 628 .. 576 630 .. 0.85 16 ? -0.0 0.0 0.94 8.6e+02 38 68 .. 634 664 .. 632 670 .. 0.84 17 ? 1.4 0.0 0.34 3.1e+02 38 68 .. 674 704 .. 672 710 .. 0.85 18 ? 4.0 0.0 0.057 52 38 73 .. 714 749 .. 712 750 .. 0.90 19 ? 4.6 0.2 0.035 32 38 97 .. 754 813 .. 752 820 .. 0.79 20 ? 3.0 0.0 0.11 1e+02 37 73 .. 793 829 .. 791 830 .. 0.91 21 ? 5.4 0.2 0.02 18 38 100 .. 834 896 .. 832 902 .. 0.82 22 ? 5.1 0.2 0.026 24 38 97 .. 914 973 .. 912 981 .. 0.80 23 ? 2.4 0.0 0.17 1.5e+02 37 72 .. 953 988 .. 952 990 .. 0.90 24 ! 7.3 0.9 0.0052 4.7 38 144 .. 994 1143 .. 992 1153 .. 0.65 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.064 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 +++++la + + gd+++A+++ e+ +e ++ +gh + FUN_002329-T1 33 KGYQNLAYAFQSLGDFRKAIEYHEKHLEIAIEAGHRV 69 68999***********************999999975 PP == domain 2 score: 2.2 bits; conditional E-value: 0.2 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ l++ y + gd+++A+++ e+ +e ++ FUN_002329-T1 74 AYRSLGNAYQSLGDFRKAIEYHEKHLEIAI 103 78899******************9888665 PP == domain 3 score: 1.9 bits; conditional E-value: 0.24 RPN7 40 edlaehyakigdlenAlkayerarekttslghk 72 l++ y + gd+++A+++ e+ +e ++ +h FUN_002329-T1 116 GSLGNAYQSLGDFRKAIEYHEKHLEIAIEVSHR 148 578999****************99988887776 PP == domain 4 score: 4.2 bits; conditional E-value: 0.049 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkid 74 a+ l++ y + gd+++A+++ ++ +e ++ gh + FUN_002329-T1 154 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVG 190 6778999********************9999999875 PP == domain 5 score: -1.8 bits; conditional E-value: 3.4 RPN7 38 aledlaehyakigdlenAlkayerarek 65 a+ l+ y + gd+++A+++ e+ +e FUN_002329-T1 194 AYGSLGIAYRSLGDFRKAIEYHEKDLEI 221 66778888999*********99986665 PP == domain 6 score: 2.2 bits; conditional E-value: 0.2 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l+ y + gd+++A+++ ++ +e ++ gh FUN_002329-T1 234 AYGNLGVAYQSLGDFRKAIEYHAKHLEIAIKIGHQ 268 57789999******************999999986 PP == domain 7 score: 2.4 bits; conditional E-value: 0.17 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l+ y + gd+++A+++ e+++e FUN_002329-T1 274 AYGNLGTAYRSLGDFRKAIEYHEKCLE 300 678999******************998 PP == domain 8 score: 1.3 bits; conditional E-value: 0.38 RPN7 33 eeirraledlaehyakigdlenAlkayerarektt 67 a+ +l++ y + gd+ +A+++ e+ +e ++ FUN_002329-T1 309 VGEGSAYGNLGNAYQSLGDFGKAIDYHEKHLEIAI 343 55557899*******************99888665 PP == domain 9 score: -0.7 bits; conditional E-value: 1.5 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ l++ y + g +++A+++ ++ +e ++ gh FUN_002329-T1 354 AYGSLGNAYQSLGVFRKAIEYHKKHLEIAIEVGHR 388 6778999******************9999999987 PP == domain 10 score: 0.0 bits; conditional E-value: 0.9 RPN7 38 aledlaehyakigdlenAlkayerarektts 68 a+ l++ y gd+++A+++ e+ +e ++ FUN_002329-T1 394 AYGSLGNAYQLLGDFRKAIEYHEKHLEIAIE 424 67789999***************99886665 PP == domain 11 score: 1.3 bits; conditional E-value: 0.38 RPN7 37 raledlaehyakigdlenAlkayerarekttslg 70 ra+ l++ y + gd+++A+++ e+ +e ++ g FUN_002329-T1 433 RAYGSLGNAYQSLGDFRKAIDYHEKHLEIAIEVG 466 578899******************9998776665 PP == domain 12 score: -1.3 bits; conditional E-value: 2.3 RPN7 37 raledlaehyakigdlenAlkayerarekttslghk 72 +a+ l + y + g +++A+++ ++ +e ++ gh FUN_002329-T1 473 NAYGSLVNAYQSLGVFRKAIEYHKKHLEIAIEVGHR 508 678889999****************99999999987 PP == domain 13 score: 0.1 bits; conditional E-value: 0.88 RPN7 38 aledlaehyakigdlenAlkayerarektts 68 a+ l++ y gd+++A+++ e+ +e ++ FUN_002329-T1 514 AYGSLGNAYQLLGDFRKAIEYHEKHLEIAIE 544 67789999***************99886665 PP == domain 14 score: -0.3 bits; conditional E-value: 1.1 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l++ y + gd+ +A+++ e+ +e ++ g FUN_002329-T1 554 AYGSLGNAYQSLGDFGKAIDYHEKHLEIAIEVG 586 678899*****************9988776665 PP == domain 15 score: 0.7 bits; conditional E-value: 0.56 RPN7 36 rraledlaehyakigdlenAlkayerarekttslghk 72 +a+ l++ y + g +++A+++ e+ +e ++ gh FUN_002329-T1 592 GNAYGSLGNAYQSLGVFRKAIEYHEKHLEIAIEVGHR 628 5788999*********************999999987 PP == domain 16 score: -0.0 bits; conditional E-value: 0.94 RPN7 38 aledlaehyakigdlenAlkayerarektts 68 a+ l++ y gd+++A+++ e+ +e ++ FUN_002329-T1 634 AYGSLGNAYQLLGDFRKAIEFHEKHLEIAIE 664 67789999***************99886665 PP == domain 17 score: 1.4 bits; conditional E-value: 0.34 RPN7 38 aledlaehyakigdlenAlkayerarektts 68 a+ l++ y + gd+++A+++ e+ +e ++ FUN_002329-T1 674 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAIE 704 678899*****************99886665 PP == domain 18 score: 4.0 bits; conditional E-value: 0.057 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ l++ y + gd+++A+++ e+ +e ++ gh + FUN_002329-T1 714 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHRV 749 678899*********************999999875 PP == domain 19 score: 4.6 bits; conditional E-value: 0.035 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskyle 97 a+ l++ y + gd+++A+++ ++ +e ++ gh + + ++gi+++ + k +e FUN_002329-T1 754 AYGSLGNAYKSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLGDFRKAIE 813 67789999**********************999998777777777777766665555555 PP == domain 20 score: 3.0 bits; conditional E-value: 0.11 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 ra+ +l+ y + gd+++A+++ ++ +e ++ +gh + FUN_002329-T1 793 RAYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEAGHRV 829 578899999*******************999999975 PP == domain 21 score: 5.4 bits; conditional E-value: 0.02 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekak 100 a+ l++ y + gd+++A+++ ++ +e ++ gh + + ++gi+++ + k +e k FUN_002329-T1 834 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGHLGIAYQSLGDFRKAIEYHK 896 6778999***************************99888888888888877777776666555 PP == domain 22 score: 5.1 bits; conditional E-value: 0.026 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskyle 97 a+ l++ y + gd+++A+++ ++ +e ++ gh + + ++gi+++ + k +e FUN_002329-T1 914 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLGDFRKAIE 973 67789999************************9998777777777777776666666655 PP == domain 23 score: 2.4 bits; conditional E-value: 0.17 RPN7 37 raledlaehyakigdlenAlkayerarekttslghk 72 ra+ +l+ y + gd+++A+++ ++ +e ++ gh FUN_002329-T1 953 RAYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEVGHR 988 578899999******************999999987 PP == domain 24 score: 7.3 bits; conditional E-value: 0.0052 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliekggdwerrnr................. 114 a+ l++ y + gd+++A+++ ++ +e ++ gh + + ++gi+++ + k +e k+ +e + + ++r FUN_002329-T1 994 AYGSLGNAYQSLGDFRKAIEYHAKHLEIAIKVGHRVGEGRAYGNLGIAYQSLGDFRKAIEYHKKHLEIAIEVDYRVGegnaygnlgtayrslgd 1087 5677888899999999999999999999999999998888888888888888888888888888888765533333344445555555555555 PP RPN7 115 ..........................lkvyeGlaalairkfkeAakllldslstft 144 + G a+++ ++f+ A +++ +++ tf FUN_002329-T1 1088 frkaieyheksleiaievghragegiAHHNIGNAYFCLGQFENALDKFGSAVETFN 1143 55555555555555555554444444444444455556666666666666666665 PP >> TMP_C Tape measure protein C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 7.8 7.1e+03 17 23 .. 8 14 .. 6 15 .. 0.92 2 ? -0.2 0.0 1.7 1.5e+03 9 23 .. 40 54 .. 38 55 .. 0.80 3 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 86 94 .. 80 95 .. 0.85 4 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 126 134 .. 120 135 .. 0.85 5 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 166 174 .. 160 175 .. 0.85 6 ? -1.7 0.0 4.9 4.5e+03 16 23 .. 207 214 .. 205 215 .. 0.87 7 ? -1.4 0.0 3.9 3.5e+03 15 23 .. 246 254 .. 241 255 .. 0.85 8 ? -1.7 0.0 4.9 4.5e+03 16 23 .. 287 294 .. 285 295 .. 0.87 9 ? 2.3 0.0 0.28 2.6e+02 15 23 .. 366 374 .. 358 375 .. 0.83 10 ? -1.6 0.0 4.6 4.2e+03 16 23 .. 407 414 .. 401 415 .. 0.88 11 ? 2.0 0.0 0.35 3.2e+02 15 23 .. 486 494 .. 481 495 .. 0.86 12 ? -1.6 0.0 4.6 4.2e+03 16 23 .. 527 534 .. 521 535 .. 0.88 13 ? 2.3 0.0 0.28 2.6e+02 15 23 .. 606 614 .. 598 615 .. 0.83 14 ? -1.5 0.0 4.2 3.8e+03 15 23 .. 686 694 .. 681 695 .. 0.86 15 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 726 734 .. 720 735 .. 0.85 16 ? -1.4 0.0 3.9 3.5e+03 15 23 .. 766 774 .. 760 775 .. 0.85 17 ? -1.4 0.0 3.9 3.5e+03 15 23 .. 806 814 .. 801 815 .. 0.85 18 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 846 854 .. 840 855 .. 0.85 19 ? -1.4 0.0 3.9 3.5e+03 15 23 .. 886 894 .. 881 895 .. 0.85 20 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 926 934 .. 920 935 .. 0.85 21 ? -1.4 0.0 3.9 3.5e+03 15 23 .. 966 974 .. 961 975 .. 0.85 22 ? -1.3 0.0 3.8 3.4e+03 15 23 .. 1006 1014 .. 1000 1015 .. 0.85 23 ? -1.4 0.0 3.9 3.5e+03 15 23 .. 1046 1054 .. 1041 1055 .. 0.85 24 ? -1.7 0.0 4.9 4.5e+03 16 23 .. 1087 1094 .. 1085 1095 .. 0.87 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 7.8 TMP_C 17 frdAVEy 23 fr+A+Ey FUN_002329-T1 8 FRKAIEY 14 9*****9 PP == domain 2 score: -0.2 bits; conditional E-value: 1.7 TMP_C 9 FAlgNagafrdAVEy 23 +A g fr+A+Ey FUN_002329-T1 40 YAFQSLGDFRKAIEY 54 56666788******9 PP == domain 3 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 86 GDFRKAIEY 94 56******9 PP == domain 4 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 126 GDFRKAIEY 134 56******9 PP == domain 5 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 166 GDFRKAIEY 174 56******9 PP == domain 6 score: -1.7 bits; conditional E-value: 4.9 TMP_C 16 afrdAVEy 23 fr+A+Ey FUN_002329-T1 207 DFRKAIEY 214 59*****9 PP == domain 7 score: -1.4 bits; conditional E-value: 3.9 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 246 GDFRKAIEY 254 56******9 PP == domain 8 score: -1.7 bits; conditional E-value: 4.9 TMP_C 16 afrdAVEy 23 fr+A+Ey FUN_002329-T1 287 DFRKAIEY 294 59*****9 PP == domain 9 score: 2.3 bits; conditional E-value: 0.28 TMP_C 15 gafrdAVEy 23 g+fr+A+Ey FUN_002329-T1 366 GVFRKAIEY 374 9*******9 PP == domain 10 score: -1.6 bits; conditional E-value: 4.6 TMP_C 16 afrdAVEy 23 fr+A+Ey FUN_002329-T1 407 DFRKAIEY 414 5******9 PP == domain 11 score: 2.0 bits; conditional E-value: 0.35 TMP_C 15 gafrdAVEy 23 g+fr+A+Ey FUN_002329-T1 486 GVFRKAIEY 494 9*******9 PP == domain 12 score: -1.6 bits; conditional E-value: 4.6 TMP_C 16 afrdAVEy 23 fr+A+Ey FUN_002329-T1 527 DFRKAIEY 534 5******9 PP == domain 13 score: 2.3 bits; conditional E-value: 0.28 TMP_C 15 gafrdAVEy 23 g+fr+A+Ey FUN_002329-T1 606 GVFRKAIEY 614 9*******9 PP == domain 14 score: -1.5 bits; conditional E-value: 4.2 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 686 GDFRKAIEY 694 56******9 PP == domain 15 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 726 GDFRKAIEY 734 56******9 PP == domain 16 score: -1.4 bits; conditional E-value: 3.9 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 766 GDFRKAIEY 774 56******9 PP == domain 17 score: -1.4 bits; conditional E-value: 3.9 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 806 GDFRKAIEY 814 56******9 PP == domain 18 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 846 GDFRKAIEY 854 56******9 PP == domain 19 score: -1.4 bits; conditional E-value: 3.9 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 886 GDFRKAIEY 894 56******9 PP == domain 20 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 926 GDFRKAIEY 934 56******9 PP == domain 21 score: -1.4 bits; conditional E-value: 3.9 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 966 GDFRKAIEY 974 56******9 PP == domain 22 score: -1.3 bits; conditional E-value: 3.8 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 1006 GDFRKAIEY 1014 56******9 PP == domain 23 score: -1.4 bits; conditional E-value: 3.9 TMP_C 15 gafrdAVEy 23 g fr+A+Ey FUN_002329-T1 1046 GDFRKAIEY 1054 56******9 PP == domain 24 score: -1.7 bits; conditional E-value: 4.9 TMP_C 16 afrdAVEy 23 fr+A+Ey FUN_002329-T1 1087 DFRKAIEY 1094 59*****9 PP >> Transferase Transferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.43 3.9e+02 273 323 .. 53 103 .. 39 114 .. 0.86 2 ? 0.8 0.0 0.23 2.1e+02 273 323 .. 133 183 .. 123 194 .. 0.84 3 ? 1.2 0.0 0.18 1.6e+02 276 324 .. 336 384 .. 329 391 .. 0.87 4 ? -1.2 0.0 0.93 8.4e+02 274 323 .. 414 463 .. 407 479 .. 0.85 5 ? -1.1 0.0 0.86 7.9e+02 275 323 .. 495 543 .. 484 563 .. 0.84 6 ? 4.5 0.0 0.017 15 276 324 .. 576 624 .. 569 645 .. 0.89 7 ? 0.8 0.0 0.23 2.1e+02 272 324 .. 692 744 .. 680 757 .. 0.86 8 ? -0.7 0.0 0.67 6.1e+02 275 323 .. 815 863 .. 807 872 .. 0.83 9 ? 0.1 0.0 0.37 3.4e+02 275 323 .. 895 943 .. 886 952 .. 0.83 10 ? 0.2 0.0 0.36 3.3e+02 275 323 .. 975 1023 .. 966 1034 .. 0.84 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.43 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 e +e+ l ia++ +r+ + + GNa++s + +a e ++ l ++ FUN_002329-T1 53 EYHEKHLEIAIEAGHRVGEGNAYRSLGNAYQSLGDFRKAIEYHEKHLEIAI 103 5566999*****************************999999999887665 PP == domain 2 score: 0.8 bits; conditional E-value: 0.23 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 e +e+ l ia+++ +r+ + ++ GNa++s + +a e + l ++ FUN_002329-T1 133 EYHEKHLEIAIEVSHRVGEGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAI 183 4556899*************************9999999888888776655 PP == domain 3 score: 1.2 bits; conditional E-value: 0.18 Transferase 276 etvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 e+ l ia+++ r+ + ++ GNa++s v+ +a e ++ l ++e FUN_002329-T1 336 EKHLEIAIEVGDRVGEGNAYGSLGNAYQSLGVFRKAIEYHKKHLEIAIE 384 578999******************************9999998877665 PP == domain 4 score: -1.2 bits; conditional E-value: 0.93 Transferase 274 eketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 +e+ l ia+++ r+ + ++ GNa++s + +a + ++ l ++ FUN_002329-T1 414 YHEKHLEIAIEVGDRVGEGRAYGSLGNAYQSLGDFRKAIDYHEKHLEIAI 463 4568999************************9999999998888887665 PP == domain 5 score: -1.1 bits; conditional E-value: 0.86 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 +++ l ia+++ +r+ + ++ GNa++ + +a e ++ l ++ FUN_002329-T1 495 HKKHLEIAIEVGHRVGEGNAYGSLGNAYQLLGDFRKAIEYHEKHLEIAI 543 45889999********************999999999888888887655 PP == domain 6 score: 4.5 bits; conditional E-value: 0.017 Transferase 276 etvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 e+ l ia+++ r+e+ ++ GNa++s v+ +a e ++ l ++e FUN_002329-T1 576 EKHLEIAIEVGDRVEEGNAYGSLGNAYQSLGVFRKAIEYHEKHLEIAIE 624 57899***********************************999987776 PP == domain 7 score: 0.8 bits; conditional E-value: 0.23 Transferase 272 deeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 e +e+ l ia+++ r+ + ++ GNa++s + +a e ++ l ++e FUN_002329-T1 692 IEYHEKHLEIAIEVGDRVGEGKAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIE 744 45567999********************************9999999987766 PP == domain 8 score: -0.7 bits; conditional E-value: 0.67 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 +++ l ia++ +r+ + ++ GNa++s + +a e + l ++ FUN_002329-T1 815 HKKHLEIAIEAGHRVGEGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAI 863 558899************************9999999888888776655 PP == domain 9 score: 0.1 bits; conditional E-value: 0.37 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 +++ l ia+++ +r+ + ++ GNa++s + +a e + l ++ FUN_002329-T1 895 HKKHLEIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAI 943 558999************************9999999888888776655 PP == domain 10 score: 0.2 bits; conditional E-value: 0.36 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsriv 323 +++ l ia+++ +r+ + ++ GNa++s + +a e + l ++ FUN_002329-T1 975 HKKHLEIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAIEYHAKHLEIAI 1023 558999************************9999999888888776655 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 1.1 1e+03 219 243 .. 36 60 .. 26 64 .. 0.87 2 ? 1.0 0.0 0.35 3.2e+02 220 243 .. 77 100 .. 71 104 .. 0.88 3 ? 2.1 0.0 0.16 1.5e+02 218 243 .. 115 140 .. 109 144 .. 0.88 4 ? 0.2 0.0 0.65 5.9e+02 219 243 .. 156 180 .. 152 183 .. 0.87 5 ? -1.4 0.0 2 1.8e+03 219 242 .. 196 219 .. 193 222 .. 0.85 6 ? -0.8 0.0 1.3 1.2e+03 220 243 .. 237 260 .. 235 263 .. 0.87 7 ? 1.5 0.0 0.25 2.3e+02 219 244 .. 276 301 .. 271 305 .. 0.85 8 ? -2.4 0.0 3.8 3.5e+03 219 243 .. 316 340 .. 313 342 .. 0.87 9 ? -1.6 0.0 2.2 2e+03 219 243 .. 356 380 .. 353 383 .. 0.85 10 ? 2.5 0.0 0.13 1.1e+02 219 243 .. 396 420 .. 391 424 .. 0.89 11 ? 0.5 0.0 0.5 4.5e+02 219 243 .. 436 460 .. 432 464 .. 0.88 12 ? 2.5 0.0 0.13 1.1e+02 219 243 .. 516 540 .. 511 544 .. 0.89 13 ? -1.9 0.0 2.8 2.6e+03 219 243 .. 556 580 .. 553 583 .. 0.88 14 ? -1.3 0.0 1.8 1.6e+03 219 243 .. 596 620 .. 590 623 .. 0.86 15 ? 1.2 0.0 0.31 2.9e+02 219 243 .. 636 660 .. 632 664 .. 0.88 16 ? 1.0 0.0 0.35 3.2e+02 219 243 .. 676 700 .. 672 704 .. 0.88 17 ? 1.4 0.0 0.27 2.4e+02 219 243 .. 716 740 .. 711 743 .. 0.88 18 ? -0.1 0.0 0.75 6.9e+02 219 243 .. 756 780 .. 752 783 .. 0.87 19 ? 0.0 0.0 0.71 6.5e+02 219 243 .. 796 820 .. 792 824 .. 0.87 20 ? 0.2 0.0 0.62 5.7e+02 219 243 .. 836 860 .. 831 863 .. 0.87 21 ? -0.2 0.0 0.86 7.9e+02 220 243 .. 877 900 .. 873 903 .. 0.87 22 ? 0.2 0.0 0.65 5.9e+02 219 243 .. 916 940 .. 912 943 .. 0.87 23 ? -0.1 0.0 0.76 6.9e+02 219 243 .. 956 980 .. 952 983 .. 0.87 24 ? 0.2 0.0 0.65 5.9e+02 219 243 .. 996 1020 .. 992 1023 .. 0.87 25 ? 0.1 0.0 0.7 6.4e+02 219 243 .. 1036 1060 .. 1032 1065 .. 0.87 26 ? 1.3 0.0 0.3 2.7e+02 219 242 .. 1076 1099 .. 1072 1103 .. 0.88 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.1 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + +A A+ lg+ rkA +y +k+++ FUN_002329-T1 36 QNLAYAFQSLGDFRKAIEYHEKHLE 60 568999***************9976 PP == domain 2 score: 1.0 bits; conditional E-value: 0.35 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 77 SLGNAYQSLGDFRKAIEYHEKHLE 100 6899****************9976 PP == domain 3 score: 2.1 bits; conditional E-value: 0.16 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 115 YGSLGNAYQSLGDFRKAIEYHEKHLE 140 67899*****************9976 PP == domain 4 score: 0.2 bits; conditional E-value: 0.65 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002329-T1 156 GSLGNAYQSLGDFRKAIEYHAKHLE 180 67899**************999875 PP == domain 5 score: -1.4 bits; conditional E-value: 2 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ lg+ rkA +y +k + FUN_002329-T1 196 GSLGIAYRSLGDFRKAIEYHEKDL 219 56888**************99865 PP == domain 6 score: -0.8 bits; conditional E-value: 1.3 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y k+++ FUN_002329-T1 237 NLGVAYQSLGDFRKAIEYHAKHLE 260 6899**************999875 PP == domain 7 score: 1.5 bits; conditional E-value: 0.25 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + +++A+ lg+ rkA +y +k ++ FUN_002329-T1 276 GNLGTAYRSLGDFRKAIEYHEKCLEI 301 6799****************997665 PP == domain 8 score: -2.4 bits; conditional E-value: 3.8 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ kA y +k+++ FUN_002329-T1 316 GNLGNAYQSLGDFGKAIDYHEKHLE 340 56899***************99875 PP == domain 9 score: -1.6 bits; conditional E-value: 2.2 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg rkA +y +k+++ FUN_002329-T1 356 GSLGNAYQSLGVFRKAIEYHKKHLE 380 57899999***********999875 PP == domain 10 score: 2.5 bits; conditional E-value: 0.13 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA +y +k+++ FUN_002329-T1 396 GSLGNAYQLLGDFRKAIEYHEKHLE 420 67899****************9976 PP == domain 11 score: 0.5 bits; conditional E-value: 0.5 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA y +k+++ FUN_002329-T1 436 GSLGNAYQSLGDFRKAIDYHEKHLE 460 67899****************9976 PP == domain 12 score: 2.5 bits; conditional E-value: 0.13 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA +y +k+++ FUN_002329-T1 516 GSLGNAYQLLGDFRKAIEYHEKHLE 540 67899****************9976 PP == domain 13 score: -1.9 bits; conditional E-value: 2.8 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ kA y +k+++ FUN_002329-T1 556 GSLGNAYQSLGDFGKAIDYHEKHLE 580 67899****************9875 PP == domain 14 score: -1.3 bits; conditional E-value: 1.8 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg rkA +y +k+++ FUN_002329-T1 596 GSLGNAYQSLGVFRKAIEYHEKHLE 620 678999*************999875 PP == domain 15 score: 1.2 bits; conditional E-value: 0.31 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ llg+ rkA ++ +k+++ FUN_002329-T1 636 GSLGNAYQLLGDFRKAIEFHEKHLE 660 67899****************9976 PP == domain 16 score: 1.0 bits; conditional E-value: 0.35 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 676 GSLGNAYRSLGDFRKAIEYHEKHLE 700 67899****************9976 PP == domain 17 score: 1.4 bits; conditional E-value: 0.27 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 716 GSLGNAYQSLGDFRKAIEYHEKHLE 740 67899****************9975 PP == domain 18 score: -0.1 bits; conditional E-value: 0.75 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002329-T1 756 GSLGNAYKSLGDFRKAIEYHAKHLE 780 67899**************999875 PP == domain 19 score: 0.0 bits; conditional E-value: 0.71 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 796 GNLGIAYQSLGDFRKAIEYHKKHLE 820 56889****************9976 PP == domain 20 score: 0.2 bits; conditional E-value: 0.62 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002329-T1 836 GSLGNAYQSLGDFRKAIEYHAKHLE 860 67899**************999875 PP == domain 21 score: -0.2 bits; conditional E-value: 0.86 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 877 HLGIAYQSLGDFRKAIEYHKKHLE 900 5788****************9875 PP == domain 22 score: 0.2 bits; conditional E-value: 0.65 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002329-T1 916 GSLGNAYQSLGDFRKAIEYHAKHLE 940 67899**************999875 PP == domain 23 score: -0.1 bits; conditional E-value: 0.76 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 956 GNLGIAYQSLGDFRKAIEYHKKHLE 980 56889****************9875 PP == domain 24 score: 0.2 bits; conditional E-value: 0.65 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002329-T1 996 GSLGNAYQSLGDFRKAIEYHAKHLE 1020 67899**************999875 PP == domain 25 score: 0.1 bits; conditional E-value: 0.7 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002329-T1 1036 GNLGIAYQSLGDFRKAIEYHKKHLE 1060 56889****************9976 PP == domain 26 score: 1.3 bits; conditional E-value: 0.3 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + +++A+ lg+ rkA +y +k + FUN_002329-T1 1076 GNLGTAYRSLGDFRKAIEYHEKSL 1099 6799***************99975 PP >> FbpC_C_terminal FbpC C-terminal regulatory nucleotide binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 1.5 1.3e+03 11 25 .. 55 69 .. 52 73 .. 0.91 2 ? 0.2 0.0 1.3 1.2e+03 11 25 .. 95 109 .. 92 114 .. 0.90 3 ? 1.6 0.0 0.49 4.5e+02 11 25 .. 175 189 .. 171 190 .. 0.93 4 ? -1.2 0.0 3.7 3.3e+03 11 25 .. 255 269 .. 252 272 .. 0.90 5 ? 0.1 0.0 1.4 1.3e+03 11 25 .. 335 349 .. 332 353 .. 0.91 6 ? 0.7 0.0 0.91 8.3e+02 11 25 .. 375 389 .. 371 393 .. 0.91 7 ? -0.1 0.0 1.6 1.5e+03 11 25 .. 415 429 .. 412 430 .. 0.92 8 ? 0.2 0.0 1.3 1.2e+03 11 25 .. 455 469 .. 452 473 .. 0.91 9 ? 0.7 0.0 0.91 8.3e+02 11 25 .. 495 509 .. 491 513 .. 0.91 10 ? -0.1 0.0 1.6 1.5e+03 11 25 .. 535 549 .. 532 550 .. 0.92 11 ? 0.2 0.0 1.3 1.2e+03 11 25 .. 575 589 .. 572 593 .. 0.91 12 ? 0.1 0.0 1.4 1.3e+03 11 25 .. 615 629 .. 611 633 .. 0.91 13 ? -0.2 0.0 1.7 1.5e+03 11 25 .. 655 669 .. 652 670 .. 0.92 14 ? -0.1 0.0 1.6 1.5e+03 11 25 .. 695 709 .. 692 710 .. 0.92 15 ? -0.0 0.0 1.5 1.4e+03 11 25 .. 735 749 .. 732 753 .. 0.91 16 ? 1.6 0.0 0.46 4.2e+02 11 25 .. 775 789 .. 771 791 .. 0.93 17 ? 0.8 0.0 0.87 8e+02 11 25 .. 815 829 .. 811 833 .. 0.91 18 ? 1.6 0.0 0.46 4.2e+02 11 25 .. 855 869 .. 851 871 .. 0.93 19 ? 0.7 0.0 0.91 8.3e+02 11 25 .. 895 909 .. 891 913 .. 0.91 20 ? 1.6 0.0 0.46 4.2e+02 11 25 .. 935 949 .. 931 951 .. 0.93 21 ? 0.7 0.0 0.91 8.3e+02 11 25 .. 975 989 .. 971 993 .. 0.91 22 ? 1.6 0.0 0.46 4.2e+02 11 25 .. 1015 1029 .. 1011 1031 .. 0.93 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 1.5 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei+++aG +V FUN_002329-T1 55 HEKHLEIAIEAGHRV 69 789**********98 PP == domain 2 score: 0.2 bits; conditional E-value: 1.3 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 95 HEKHLEIAIEVGDRV 109 789**********99 PP == domain 3 score: 1.6 bits; conditional E-value: 0.49 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002329-T1 175 HAKHLEIAIKVGHRV 189 89**********998 PP == domain 4 score: -1.2 bits; conditional E-value: 3.7 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei+++ G +V FUN_002329-T1 255 HAKHLEIAIKIGHQV 269 89*********9887 PP == domain 5 score: 0.1 bits; conditional E-value: 1.4 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 335 HEKHLEIAIEVGDRV 349 789**********98 PP == domain 6 score: 0.7 bits; conditional E-value: 0.91 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei++++G +V FUN_002329-T1 375 HKKHLEIAIEVGHRV 389 899**********98 PP == domain 7 score: -0.1 bits; conditional E-value: 1.6 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 415 HEKHLEIAIEVGDRV 429 789*********998 PP == domain 8 score: 0.2 bits; conditional E-value: 1.3 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 455 HEKHLEIAIEVGDRV 469 789**********99 PP == domain 9 score: 0.7 bits; conditional E-value: 0.91 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei++++G +V FUN_002329-T1 495 HKKHLEIAIEVGHRV 509 899**********98 PP == domain 10 score: -0.1 bits; conditional E-value: 1.6 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 535 HEKHLEIAIEVGDRV 549 789*********998 PP == domain 11 score: 0.2 bits; conditional E-value: 1.3 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 575 HEKHLEIAIEVGDRV 589 789**********99 PP == domain 12 score: 0.1 bits; conditional E-value: 1.4 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 615 HEKHLEIAIEVGHRV 629 789**********98 PP == domain 13 score: -0.2 bits; conditional E-value: 1.7 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 655 HEKHLEIAIEVGDRV 669 789*********998 PP == domain 14 score: -0.1 bits; conditional E-value: 1.6 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 695 HEKHLEIAIEVGDRV 709 789*********998 PP == domain 15 score: -0.0 bits; conditional E-value: 1.5 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002329-T1 735 HEKHLEIAIEVGHRV 749 789**********98 PP == domain 16 score: 1.6 bits; conditional E-value: 0.46 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002329-T1 775 HAKHLEIAIKVGHRV 789 89**********998 PP == domain 17 score: 0.8 bits; conditional E-value: 0.87 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei+++aG +V FUN_002329-T1 815 HKKHLEIAIEAGHRV 829 899**********98 PP == domain 18 score: 1.6 bits; conditional E-value: 0.46 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002329-T1 855 HAKHLEIAIKVGHRV 869 89**********998 PP == domain 19 score: 0.7 bits; conditional E-value: 0.91 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei++++G +V FUN_002329-T1 895 HKKHLEIAIEVGHRV 909 899**********98 PP == domain 20 score: 1.6 bits; conditional E-value: 0.46 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002329-T1 935 HAKHLEIAIKVGHRV 949 89**********998 PP == domain 21 score: 0.7 bits; conditional E-value: 0.91 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei++++G +V FUN_002329-T1 975 HKKHLEIAIEVGHRV 989 899**********98 PP == domain 22 score: 1.6 bits; conditional E-value: 0.46 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002329-T1 1015 HAKHLEIAIKVGHRV 1029 89**********998 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.1 0.9 8.2e+02 5 46 .. 46 93 .. 42 102 .. 0.70 2 ? 0.2 0.0 1.5 1.3e+03 5 46 .. 86 133 .. 82 142 .. 0.63 3 ? 1.0 0.0 0.87 7.9e+02 5 46 .. 126 173 .. 122 181 .. 0.70 4 ? 0.6 0.0 1.1 1e+03 24 46 .. 231 253 .. 202 260 .. 0.70 5 ? 6.3 0.0 0.018 17 4 45 .. 285 332 .. 282 339 .. 0.93 6 ? -2.0 0.0 7.2 6.5e+03 30 46 .. 397 413 .. 392 421 .. 0.69 7 ? 0.2 0.0 1.5 1.4e+03 5 45 .. 406 452 .. 404 460 .. 0.68 8 ? -0.9 0.1 3.2 2.9e+03 5 19 .. 526 540 .. 514 576 .. 0.53 9 ? -1.2 0.0 4 3.6e+03 27 47 .. 634 654 .. 630 662 .. 0.79 10 ? 1.1 0.0 0.79 7.2e+02 5 46 .. 686 733 .. 682 742 .. 0.70 11 ? 0.2 0.0 1.5 1.4e+03 5 46 .. 726 773 .. 722 782 .. 0.68 12 ? 1.3 0.0 0.66 6.1e+02 24 46 .. 791 813 .. 764 822 .. 0.72 13 ? 1.5 0.0 0.6 5.5e+02 5 46 .. 806 853 .. 802 862 .. 0.73 14 ? 0.5 0.0 1.2 1.1e+03 24 46 .. 871 893 .. 844 902 .. 0.71 15 ? 0.8 0.0 0.96 8.8e+02 5 46 .. 886 933 .. 882 942 .. 0.69 16 ? 1.3 0.0 0.7 6.4e+02 24 46 .. 951 973 .. 924 981 .. 0.72 17 ? 0.8 0.0 0.96 8.8e+02 5 46 .. 966 1013 .. 962 1022 .. 0.69 18 ? 1.4 0.0 0.62 5.6e+02 23 46 .. 1030 1053 .. 1002 1062 .. 0.71 19 ? 1.4 0.0 0.63 5.7e+02 5 46 .. 1046 1093 .. 1042 1102 .. 0.65 20 ? -0.2 0.0 2 1.8e+03 4 42 .. 1085 1129 .. 1082 1133 .. 0.66 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.9 TPR_19 5 gdydeAlalLeqalae..dPd....naearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + + a+ L++a+ lg++ +A++ FUN_002329-T1 46 GDFRKAIEYHEKHLEIaiEAGhrvgEGNAYRSLGNAYQSLGDFRKAIE 93 777777777777544422222344577888889999999999999986 PP == domain 2 score: 0.2 bits; conditional E-value: 1.5 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + ++ L++a+ lg++ +A++ FUN_002329-T1 86 GDFRKAIEYHEKHLEIAIEvgdrvgEGNVYGSLGNAYQSLGDFRKAIE 133 666666666666444422222223366677778888888888888876 PP == domain 3 score: 1.0 bits; conditional E-value: 0.87 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + a+ L++a+ lg++ +A++ FUN_002329-T1 126 GDFRKAIEYHEKHLEIaievshRVGEGNAYGSLGNAYQSLGDFRKAIE 173 777777777777554422222233478888899999999999999986 PP == domain 4 score: 0.6 bits; conditional E-value: 1.1 TPR_19 24 naearllLArallalgrldeAea 46 a+ +L+ a+ lg++ +A++ FUN_002329-T1 231 EGVAYGNLGVAYQSLGDFRKAIE 253 56788899999999999999986 PP == domain 5 score: 6.3 bits; conditional E-value: 0.018 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAe 45 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A+ FUN_002329-T1 285 LGDFRKAIEYHEKCLEIAKEvsgrvgEGSAYGNLGNAYQSLGDFGKAI 332 69***************999999999******************9997 PP == domain 6 score: -2.0 bits; conditional E-value: 7.2 TPR_19 30 lLArallalgrldeAea 46 L++a+ lg++ +A++ FUN_002329-T1 397 SLGNAYQLLGDFRKAIE 413 56777777777777765 PP == domain 7 score: 0.2 bits; conditional E-value: 1.5 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAe 45 gd+ +A+++ e+ l+++ + +a+ L++a+ lg++ +A+ FUN_002329-T1 406 GDFRKAIEYHEKHLEIAIEvgdrvgEGRAYGSLGNAYQSLGDFRKAI 452 66677777766655552222223337788888999999999999997 PP == domain 8 score: -0.9 bits; conditional E-value: 3.2 TPR_19 5 gdydeAlalLeqala 19 gd+ +A+++ e+ l+ FUN_002329-T1 526 GDFRKAIEYHEKHLE 540 455555555554333 PP == domain 9 score: -1.2 bits; conditional E-value: 4 TPR_19 27 arllLArallalgrldeAeal 47 a+ L++a+ lg++ +A+++ FUN_002329-T1 634 AYGSLGNAYQLLGDFRKAIEF 654 666789999999999999876 PP == domain 10 score: 1.1 bits; conditional E-value: 0.79 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002329-T1 686 GDFRKAIEYHEKHLEIAIEvgdrvgEGKAYGSLGNAYQSLGDFRKAIE 733 777777777777555522222334477888889999999999999986 PP == domain 11 score: 0.2 bits; conditional E-value: 1.5 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002329-T1 726 GDFRKAIEYHEKHLEIAIEvghrvgEGNAYGSLGNAYKSLGDFRKAIE 773 677777777776555522222233377788888899999999998876 PP == domain 12 score: 1.3 bits; conditional E-value: 0.66 TPR_19 24 naearllLArallalgrldeAea 46 +a+ +L+ a+ lg++ +A++ FUN_002329-T1 791 EGRAYGNLGIAYQSLGDFRKAIE 813 67899999999999999999987 PP == domain 13 score: 1.5 bits; conditional E-value: 0.6 TPR_19 5 gdydeAlalLeqalae..dPd....naearllLArallalgrldeAea 46 gd+ +A+++ ++ l++ + + a+ L++a+ lg++ +A++ FUN_002329-T1 806 GDFRKAIEYHKKHLEIaiEAGhrvgEGNAYGSLGNAYQSLGDFRKAIE 853 788888888888554433222355588899999999999999999987 PP == domain 14 score: 0.5 bits; conditional E-value: 1.2 TPR_19 24 naearllLArallalgrldeAea 46 +a+ L+ a+ lg++ +A++ FUN_002329-T1 871 EGRAYGHLGIAYQSLGDFRKAIE 893 67788899999999999999986 PP == domain 15 score: 0.8 bits; conditional E-value: 0.96 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ ++ l+++ + a+ L++a+ lg++ +A++ FUN_002329-T1 886 GDFRKAIEYHKKHLEIAIEvghrvgEGNAYGSLGNAYQSLGDFRKAIE 933 667777777776555522222233377888889999999999999986 PP == domain 16 score: 1.3 bits; conditional E-value: 0.7 TPR_19 24 naearllLArallalgrldeAea 46 +a+ +L+ a+ lg++ +A++ FUN_002329-T1 951 EGRAYGNLGIAYQSLGDFRKAIE 973 67899999999999999999987 PP == domain 17 score: 0.8 bits; conditional E-value: 0.96 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ ++ l+++ + a+ L++a+ lg++ +A++ FUN_002329-T1 966 GDFRKAIEYHKKHLEIAIEvghrvgEGNAYGSLGNAYQSLGDFRKAIE 1013 667777777776555522222233377888889999999999999986 PP == domain 18 score: 1.4 bits; conditional E-value: 0.62 TPR_19 23 dnaearllLArallalgrldeAea 46 + +a+ +L+ a+ lg++ +A++ FUN_002329-T1 1030 GEGRAYGNLGIAYQSLGDFRKAIE 1053 467899999999999999999987 PP == domain 19 score: 1.4 bits; conditional E-value: 0.63 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ ++ l++ + a+ +L+ a+ lg++ +A++ FUN_002329-T1 1046 GDFRKAIEYHKKHLEIaievdyRVGEGNAYGNLGTAYRSLGDFRKAIE 1093 666777777666444422222233477788888888888888888876 PP == domain 20 score: -0.2 bits; conditional E-value: 2 TPR_19 4 egdydeAlalLeqalae......dPdnaearllLArallalgrld 42 gd+ +A+++ e+ l++ + a+ + ++a++ lg+++ FUN_002329-T1 1085 LGDFRKAIEYHEKSLEIaievghRAGEGIAHHNIGNAYFCLGQFE 1129 699*******99999874444445555555556666666666555 PP >> DUF8155 Domain of unknown function (DUF8155) N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.1 0.61 5.6e+02 80 113 .. 98 135 .. 94 159 .. 0.70 2 ? -0.4 0.0 2 1.8e+03 80 133 .. 138 199 .. 129 202 .. 0.58 3 ? 2.8 0.1 0.21 1.9e+02 80 117 .. 338 380 .. 325 399 .. 0.74 4 ? 0.9 0.1 0.8 7.3e+02 80 99 .. 418 437 .. 377 457 .. 0.61 5 ? 6.5 0.0 0.015 13 80 113 .. 458 495 .. 454 507 .. 0.79 6 ? -1.2 0.0 3.6 3.3e+03 80 101 .. 498 519 .. 489 541 .. 0.82 7 ? 1.7 0.0 0.46 4.2e+02 80 113 .. 538 575 .. 534 581 .. 0.70 8 ? 3.9 0.1 0.091 83 80 113 .. 578 615 .. 575 628 .. 0.72 9 ? 1.9 0.1 0.37 3.4e+02 80 113 .. 658 695 .. 655 719 .. 0.60 10 ? 1.0 0.0 0.74 6.7e+02 80 102 .. 698 720 .. 689 744 .. 0.73 11 ? 0.6 0.1 0.98 9e+02 80 118 .. 738 781 .. 734 802 .. 0.63 12 ? 0.5 0.1 1 9.3e+02 80 118 .. 818 861 .. 808 882 .. 0.67 13 ? 0.7 0.1 0.92 8.4e+02 80 118 .. 898 941 .. 889 962 .. 0.65 14 ? 0.6 0.1 0.98 9e+02 80 118 .. 978 1021 .. 972 1042 .. 0.64 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.61 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnh 113 h+e a+e+gdrv G+ G+l ++ G f + ++ h FUN_002329-T1 98 HLEIAIEVGDRVGEGNVYGSLGNAyqslGDFRKAIEYH 135 89999********9997665533211146666655554 PP == domain 2 score: -0.4 bits; conditional E-value: 2 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnhv.hlgfre...kdanllrasGslp 133 h+e a+e+++rv G++ G+l ++ G f + ++ h hl++ + + ra Gsl FUN_002329-T1 138 HLEIAIEVSHRVGEGNAYGSLGNAyqslGDFRKAIEYHAkHLEIAIkvgHRVGEGRAYGSLG 199 77778888888888876554433222257777766666445555430012334456666665 PP == domain 3 score: 2.8 bits; conditional E-value: 0.21 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnhv.hlg 117 h+e a+e+gdrv G++ G+l ++ G f + ++ h hl+ FUN_002329-T1 338 HLEIAIEVGDRVGEGNAYGSLGNAyqslGVFRKAIEYHKkHLE 380 89999*********99766654332225777777766632555 PP == domain 4 score: 0.9 bits; conditional E-value: 0.8 DUF8155 80 hvepaveagdrvevGdslGe 99 h+e a+e+gdrv G + G+ FUN_002329-T1 418 HLEIAIEVGDRVGEGRAYGS 437 55556666666666655444 PP == domain 5 score: 6.5 bits; conditional E-value: 0.015 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnh 113 h+e a+e+gdrve G++ G+lv++ G f + ++ h FUN_002329-T1 458 HLEIAIEVGDRVEEGNAYGSLVNAyqslGVFRKAIEYH 495 8999*****************98755557777766665 PP == domain 6 score: -1.2 bits; conditional E-value: 3.6 DUF8155 80 hvepaveagdrvevGdslGelv 101 h+e a+e+g+rv G++ G+l FUN_002329-T1 498 HLEIAIEVGHRVGEGNAYGSLG 519 89999**********9999875 PP == domain 7 score: 1.7 bits; conditional E-value: 0.46 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnh 113 h+e a+e+gdrv G++ G+l ++ G f++ +d h FUN_002329-T1 538 HLEIAIEVGDRVGEGKAYGSLGNAyqslGDFGKAIDYH 575 89999**********97666543322257777777766 PP == domain 8 score: 3.9 bits; conditional E-value: 0.091 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnh 113 h+e a+e+gdrve G++ G+l ++ G f + ++ h FUN_002329-T1 578 HLEIAIEVGDRVEEGNAYGSLGNAyqslGVFRKAIEYH 615 8999***********98766543322257777766665 PP == domain 9 score: 1.9 bits; conditional E-value: 0.37 DUF8155 80 hvepaveagdrvevGds...lGelvrs.GffapWvdnh 113 h+e a+e+gdrv G++ lG+ rs G f + ++ h FUN_002329-T1 658 HLEIAIEVGDRVGEGKAygsLGNAYRSlGDFRKAIEYH 695 77888888888888875111444444446666555544 PP == domain 10 score: 1.0 bits; conditional E-value: 0.74 DUF8155 80 hvepaveagdrvevGdslGelvr 102 h+e a+e+gdrv G++ G+l + FUN_002329-T1 698 HLEIAIEVGDRVGEGKAYGSLGN 720 89999**********98776643 PP == domain 11 score: 0.6 bits; conditional E-value: 0.98 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnhv.hlgf 118 h+e a+e+g+rv G++ G+l ++ G f + ++ h hl++ FUN_002329-T1 738 HLEIAIEVGHRVGEGNAYGSLGNAykslGDFRKAIEYHAkHLEI 781 88889999999999987655433222257777766666435554 PP == domain 12 score: 0.5 bits; conditional E-value: 1 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnhv.hlgf 118 h+e a+eag+rv G++ G+l ++ G f + ++ h hl++ FUN_002329-T1 818 HLEIAIEAGHRVGEGNAYGSLGNAyqslGDFRKAIEYHAkHLEI 861 88889999999999987665543222257777766666435554 PP == domain 13 score: 0.7 bits; conditional E-value: 0.92 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnhv.hlgf 118 h+e a+e+g+rv G++ G+l ++ G f + ++ h hl++ FUN_002329-T1 898 HLEIAIEVGHRVGEGNAYGSLGNAyqslGDFRKAIEYHAkHLEI 941 88889999999999987665533222257777766666435554 PP == domain 14 score: 0.6 bits; conditional E-value: 0.98 DUF8155 80 hvepaveagdrvevGdslGelvrs....GffapWvdnhv.hlgf 118 h+e a+e+g+rv G++ G+l ++ G f + ++ h hl++ FUN_002329-T1 978 HLEIAIEVGHRVGEGNAYGSLGNAyqslGDFRKAIEYHAkHLEI 1021 88889999999999987665533222257777766666435554 PP >> CAMSAP_CC1 Spectrin-binding region of Ca2+-Calmodulin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 1.2 1.1e+03 27 41 .. 49 63 .. 45 70 .. 0.84 2 ? -0.7 0.0 2 1.9e+03 27 40 .. 89 102 .. 85 104 .. 0.86 3 ? -0.4 0.0 1.7 1.5e+03 27 41 .. 129 143 .. 125 148 .. 0.86 4 ? -0.7 0.0 2.2 2e+03 27 41 .. 169 183 .. 165 188 .. 0.86 5 ? -1.4 0.0 3.5 3.2e+03 27 40 .. 209 222 .. 205 224 .. 0.85 6 ? -0.7 0.0 2.2 2e+03 27 41 .. 249 263 .. 245 268 .. 0.86 7 ? 3.7 0.1 0.087 79 27 40 .. 369 382 .. 368 388 .. 0.90 8 ? -0.7 0.0 2 1.9e+03 27 40 .. 409 422 .. 405 424 .. 0.86 9 ? 3.7 0.1 0.087 79 27 40 .. 489 502 .. 488 508 .. 0.90 10 ? -0.7 0.0 2 1.9e+03 27 40 .. 529 542 .. 525 544 .. 0.86 11 ? -1.4 0.2 3.4 3.1e+03 27 40 .. 609 622 .. 609 625 .. 0.89 12 ? -2.7 0.1 8.5 7.8e+03 27 40 .. 649 662 .. 647 664 .. 0.86 13 ? -0.7 0.0 2 1.9e+03 27 40 .. 689 702 .. 685 704 .. 0.86 14 ? -0.5 0.0 1.9 1.7e+03 27 40 .. 729 742 .. 725 746 .. 0.87 15 ? -0.7 0.0 2.2 2e+03 27 41 .. 769 783 .. 765 788 .. 0.86 16 ? 4.8 0.0 0.039 35 27 41 .. 809 823 .. 805 831 .. 0.85 17 ? -0.7 0.0 2.2 2e+03 27 41 .. 849 863 .. 845 868 .. 0.86 18 ? 4.3 0.0 0.058 53 27 40 .. 889 902 .. 885 908 .. 0.88 19 ? -0.7 0.0 2.2 2e+03 27 41 .. 929 943 .. 925 948 .. 0.86 20 ? 4.3 0.0 0.058 53 27 40 .. 969 982 .. 965 988 .. 0.88 21 ? -0.7 0.0 2.2 2e+03 27 41 .. 1009 1023 .. 1005 1028 .. 0.86 22 ? 4.2 0.0 0.064 58 27 40 .. 1049 1062 .. 1045 1065 .. 0.88 23 ? -0.1 0.0 1.4 1.3e+03 27 40 .. 1089 1102 .. 1085 1108 .. 0.87 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 49 RKAIEYHEKHLEIAI 63 9*********99776 PP == domain 2 score: -0.7 bits; conditional E-value: 2 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 89 RKAIEYHEKHLEIA 102 9********99976 PP == domain 3 score: -0.4 bits; conditional E-value: 1.7 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 129 RKAIEYHEKHLEIAI 143 9********999765 PP == domain 4 score: -0.7 bits; conditional E-value: 2.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 169 RKAIEYHAKHLEIAI 183 9********999876 PP == domain 5 score: -1.4 bits; conditional E-value: 3.5 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 209 RKAIEYHEKDLEIA 222 9*****99999976 PP == domain 6 score: -0.7 bits; conditional E-value: 2.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 249 RKAIEYHAKHLEIAI 263 9********999876 PP == domain 7 score: 3.7 bits; conditional E-value: 0.087 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE K+ +E a FUN_002329-T1 369 RKAIEYHKKHLEIA 382 9***********77 PP == domain 8 score: -0.7 bits; conditional E-value: 2 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 409 RKAIEYHEKHLEIA 422 9********99976 PP == domain 9 score: 3.7 bits; conditional E-value: 0.087 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE K+ +E a FUN_002329-T1 489 RKAIEYHKKHLEIA 502 9***********77 PP == domain 10 score: -0.7 bits; conditional E-value: 2 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 529 RKAIEYHEKHLEIA 542 9********99976 PP == domain 11 score: -1.4 bits; conditional E-value: 3.4 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 609 RKAIEYHEKHLEIA 622 9********99976 PP == domain 12 score: -2.7 bits; conditional E-value: 8.5 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 649 RKAIEFHEKHLEIA 662 9****999999976 PP == domain 13 score: -0.7 bits; conditional E-value: 2 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 689 RKAIEYHEKHLEIA 702 9********99976 PP == domain 14 score: -0.5 bits; conditional E-value: 1.9 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE + +E a FUN_002329-T1 729 RKAIEYHEKHLEIA 742 9********99976 PP == domain 15 score: -0.7 bits; conditional E-value: 2.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 769 RKAIEYHAKHLEIAI 783 9********999876 PP == domain 16 score: 4.8 bits; conditional E-value: 0.039 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE K+ +E a+ FUN_002329-T1 809 RKAIEYHKKHLEIAI 823 9***********876 PP == domain 17 score: -0.7 bits; conditional E-value: 2.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 849 RKAIEYHAKHLEIAI 863 9********999876 PP == domain 18 score: 4.3 bits; conditional E-value: 0.058 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE K+ +E a FUN_002329-T1 889 RKAIEYHKKHLEIA 902 9***********77 PP == domain 19 score: -0.7 bits; conditional E-value: 2.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 929 RKAIEYHAKHLEIAI 943 9********999876 PP == domain 20 score: 4.3 bits; conditional E-value: 0.058 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE K+ +E a FUN_002329-T1 969 RKAIEYHKKHLEIA 982 9***********77 PP == domain 21 score: -0.7 bits; conditional E-value: 2.2 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002329-T1 1009 RKAIEYHAKHLEIAI 1023 9********999876 PP == domain 22 score: 4.2 bits; conditional E-value: 0.064 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE K+ +E a FUN_002329-T1 1049 RKAIEYHKKHLEIA 1062 9**********976 PP == domain 23 score: -0.1 bits; conditional E-value: 1.4 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE +++E a FUN_002329-T1 1089 RKAIEYHEKSLEIA 1102 9*********9976 PP >> HAT_Syf1_M Pre-mRNA-splicing factor SYF1 middle HAT repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.0 8.4 7.7e+03 79 108 .. 111 140 .. 104 145 .. 0.84 2 ? -0.7 0.0 1.6 1.5e+03 79 115 .. 431 467 .. 395 489 .. 0.87 3 ? -0.7 0.0 1.6 1.5e+03 79 115 .. 551 587 .. 544 615 .. 0.87 4 ? -3.1 0.0 8.9 8.1e+03 79 112 .. 671 704 .. 669 718 .. 0.86 5 ? 3.4 0.0 0.093 85 80 117 .. 1112 1149 .. 1105 1163 .. 0.86 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 8.4 HAT_Syf1_M 79 aGklwtsLadyyirlgefekaRdvfeegit 108 G+++ sL + y +lg+f ka + +e+ ++ FUN_002329-T1 111 EGNVYGSLGNAYQSLGDFRKAIEYHEKHLE 140 589999**************9988887665 PP == domain 2 score: -0.7 bits; conditional E-value: 1.6 HAT_Syf1_M 79 aGklwtsLadyyirlgefekaRdvfeegittvmtvrd 115 G+ + sL + y +lg+f ka d +e+ ++ + v d FUN_002329-T1 431 EGRAYGSLGNAYQSLGDFRKAIDYHEKHLEIAIEVGD 467 588999999************9999998887766655 PP == domain 3 score: -0.7 bits; conditional E-value: 1.6 HAT_Syf1_M 79 aGklwtsLadyyirlgefekaRdvfeegittvmtvrd 115 Gk + sL + y +lg+f ka d +e+ ++ + v d FUN_002329-T1 551 EGKAYGSLGNAYQSLGDFGKAIDYHEKHLEIAIEVGD 587 58999******************99998887766655 PP == domain 4 score: -3.1 bits; conditional E-value: 8.9 HAT_Syf1_M 79 aGklwtsLadyyirlgefekaRdvfeegittvmt 112 Gk + sL + y +lg+f ka + +e+ ++ + FUN_002329-T1 671 EGKAYGSLGNAYRSLGDFRKAIEYHEKHLEIAIE 704 599999***************9999888776655 PP == domain 5 score: 3.4 bits; conditional E-value: 0.093 HAT_Syf1_M 80 GklwtsLadyyirlgefekaRdvfeegittvmtvrdFt 117 G + ++ + y lg+fe a d f +++t t+r F FUN_002329-T1 1112 GIAHHNIGNAYFCLGQFENALDKFGSAVETFNTLRSFL 1149 55566777889999*********************995 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.1 1.7 1.6e+03 33 58 .. 36 61 .. 34 68 .. 0.81 2 ? 2.5 0.0 0.23 2.1e+02 32 57 .. 75 100 .. 72 108 .. 0.84 3 ? -0.0 0.0 1.4 1.3e+03 36 56 .. 119 139 .. 115 146 .. 0.81 4 ? -1.0 0.1 2.8 2.6e+03 36 51 .. 159 174 .. 154 182 .. 0.83 5 ? -0.2 0.0 1.6 1.5e+03 35 51 .. 198 214 .. 193 224 .. 0.83 6 ? 1.8 0.0 0.39 3.6e+02 34 51 .. 237 254 .. 234 262 .. 0.85 7 ? 2.1 0.0 0.3 2.8e+02 33 59 .. 276 302 .. 273 308 .. 0.87 8 ? 0.4 0.0 1.1 9.7e+02 32 56 .. 315 339 .. 312 347 .. 0.81 9 ? -1.0 0.0 3 2.7e+03 36 57 .. 399 420 .. 395 428 .. 0.82 10 ? -0.0 0.0 1.4 1.3e+03 35 56 .. 438 459 .. 431 468 .. 0.79 11 ? -1.2 0.0 3.3 3e+03 36 56 .. 519 539 .. 515 546 .. 0.82 12 ? -0.8 0.0 2.5 2.3e+03 36 57 .. 559 580 .. 554 588 .. 0.81 13 ? -2.1 0.0 6.2 5.6e+03 36 55 .. 599 618 .. 595 622 .. 0.80 14 ? 0.0 0.0 1.4 1.3e+03 36 56 .. 719 739 .. 714 744 .. 0.80 15 ? 4.1 0.1 0.071 65 31 51 .. 794 814 .. 791 828 .. 0.83 16 ? -1.0 0.1 2.8 2.6e+03 36 51 .. 839 854 .. 834 862 .. 0.83 17 ? 2.5 0.0 0.24 2.2e+02 35 51 .. 878 894 .. 872 902 .. 0.85 18 ? -1.0 0.1 2.8 2.6e+03 36 51 .. 919 934 .. 914 942 .. 0.83 19 ? 3.9 0.0 0.088 80 31 51 .. 954 974 .. 951 983 .. 0.86 20 ? -1.0 0.1 2.8 2.6e+03 36 51 .. 999 1014 .. 994 1022 .. 0.83 21 ? 3.9 0.0 0.088 80 31 51 .. 1034 1054 .. 1031 1063 .. 0.86 22 ? -1.2 0.0 3.2 2.9e+03 33 53 .. 1076 1096 .. 1073 1103 .. 0.80 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 1.7 TPR_9 33 rdrGllyaqlgcleaAladLeaylal 58 ++ + + + lg++ +A+++ e+ l++ FUN_002329-T1 36 QNLAYAFQSLGDFRKAIEYHEKHLEI 61 6778999**********987777765 PP == domain 2 score: 2.5 bits; conditional E-value: 0.23 TPR_9 32 rrdrGllyaqlgcleaAladLeayla 57 +r G +y+ lg++ +A+++ e+ l+ FUN_002329-T1 75 YRSLGNAYQSLGDFRKAIEYHEKHLE 100 788999************98776665 PP == domain 3 score: -0.0 bits; conditional E-value: 1.4 TPR_9 36 GllyaqlgcleaAladLeayl 56 G +y+ lg++ +A+++ e+ l FUN_002329-T1 119 GNAYQSLGDFRKAIEYHEKHL 139 7799*********99866655 PP == domain 4 score: -1.0 bits; conditional E-value: 2.8 TPR_9 36 GllyaqlgcleaAlad 51 G +y+ lg++ +A+++ FUN_002329-T1 159 GNAYQSLGDFRKAIEY 174 77999*******9986 PP == domain 5 score: -0.2 bits; conditional E-value: 1.6 TPR_9 35 rGllyaqlgcleaAlad 51 G++y lg++ +A+++ FUN_002329-T1 198 LGIAYRSLGDFRKAIEY 214 79************986 PP == domain 6 score: 1.8 bits; conditional E-value: 0.39 TPR_9 34 drGllyaqlgcleaAlad 51 + G +y+ lg++ +A+++ FUN_002329-T1 237 NLGVAYQSLGDFRKAIEY 254 789************986 PP == domain 7 score: 2.1 bits; conditional E-value: 0.3 TPR_9 33 rdrGllyaqlgcleaAladLeaylala 59 + G +y lg++ +A+++ e++l++a FUN_002329-T1 276 GNLGTAYRSLGDFRKAIEYHEKCLEIA 302 678999*************99999887 PP == domain 8 score: 0.4 bits; conditional E-value: 1.1 TPR_9 32 rrdrGllyaqlgcleaAladLeayl 56 + + G +y+ lg++ +A+++ e+ l FUN_002329-T1 315 YGNLGNAYQSLGDFGKAIDYHEKHL 339 5678999**********99866655 PP == domain 9 score: -1.0 bits; conditional E-value: 3 TPR_9 36 GllyaqlgcleaAladLeayla 57 G +y+ lg++ +A+++ e+ l+ FUN_002329-T1 399 GNAYQLLGDFRKAIEYHEKHLE 420 77999*********98776665 PP == domain 10 score: -0.0 bits; conditional E-value: 1.4 TPR_9 35 rGllyaqlgcleaAladLeayl 56 G +y+ lg++ +A+++ e+ l FUN_002329-T1 438 LGNAYQSLGDFRKAIDYHEKHL 459 5789999999999998766655 PP == domain 11 score: -1.2 bits; conditional E-value: 3.3 TPR_9 36 GllyaqlgcleaAladLeayl 56 G +y+ lg++ +A+++ e+ l FUN_002329-T1 519 GNAYQLLGDFRKAIEYHEKHL 539 77999********99866655 PP == domain 12 score: -0.8 bits; conditional E-value: 2.5 TPR_9 36 GllyaqlgcleaAladLeayla 57 G +y+ lg++ +A+++ e+ l+ FUN_002329-T1 559 GNAYQSLGDFGKAIDYHEKHLE 580 7799*********998666655 PP == domain 13 score: -2.1 bits; conditional E-value: 6.2 TPR_9 36 GllyaqlgcleaAladLeay 55 G +y+ lg + +A+++ e+ FUN_002329-T1 599 GNAYQSLGVFRKAIEYHEKH 618 7799*********9986665 PP == domain 14 score: 0.0 bits; conditional E-value: 1.4 TPR_9 36 GllyaqlgcleaAladLeayl 56 G +y+ lg++ +A+++ e+ l FUN_002329-T1 719 GNAYQSLGDFRKAIEYHEKHL 739 7799*********99866655 PP == domain 15 score: 4.1 bits; conditional E-value: 0.071 TPR_9 31 errdrGllyaqlgcleaAlad 51 + + G++y+ lg++ +A+++ FUN_002329-T1 794 AYGNLGIAYQSLGDFRKAIEY 814 56789*************997 PP == domain 16 score: -1.0 bits; conditional E-value: 2.8 TPR_9 36 GllyaqlgcleaAlad 51 G +y+ lg++ +A+++ FUN_002329-T1 839 GNAYQSLGDFRKAIEY 854 77999*******9986 PP == domain 17 score: 2.5 bits; conditional E-value: 0.24 TPR_9 35 rGllyaqlgcleaAlad 51 G++y+ lg++ +A+++ FUN_002329-T1 878 LGIAYQSLGDFRKAIEY 894 79************986 PP == domain 18 score: -1.0 bits; conditional E-value: 2.8 TPR_9 36 GllyaqlgcleaAlad 51 G +y+ lg++ +A+++ FUN_002329-T1 919 GNAYQSLGDFRKAIEY 934 77999*******9986 PP == domain 19 score: 3.9 bits; conditional E-value: 0.088 TPR_9 31 errdrGllyaqlgcleaAlad 51 + + G++y+ lg++ +A+++ FUN_002329-T1 954 AYGNLGIAYQSLGDFRKAIEY 974 56789*************986 PP == domain 20 score: -1.0 bits; conditional E-value: 2.8 TPR_9 36 GllyaqlgcleaAlad 51 G +y+ lg++ +A+++ FUN_002329-T1 999 GNAYQSLGDFRKAIEY 1014 77999*******9986 PP == domain 21 score: 3.9 bits; conditional E-value: 0.088 TPR_9 31 errdrGllyaqlgcleaAlad 51 + + G++y+ lg++ +A+++ FUN_002329-T1 1034 AYGNLGIAYQSLGDFRKAIEY 1054 56789*************986 PP == domain 22 score: -1.2 bits; conditional E-value: 3.2 TPR_9 33 rdrGllyaqlgcleaAladLe 53 + G +y lg++ +A+++ e FUN_002329-T1 1076 GNLGTAYRSLGDFRKAIEYHE 1096 57899999********99755 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1605 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 460 (0.0180074); expected 510.9 (0.02) Passed bias filter: 417 (0.0163241); expected 510.9 (0.02) Passed Vit filter: 56 (0.00219221); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 28 [number of targets reported over threshold] # CPU time: 0.63u 0.40s 00:00:01.03 Elapsed: 00:00:00.47 # Mc/sec: 13733.31 // Query: FUN_002330-T1 [L=269] Description: FUN_002330 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.9e-14 52.6 0.3 2.1e-10 41.1 0.1 2.2 2 Proteasome Proteasome subunit 1e-05 25.3 1.3 1.9e-05 24.5 1.3 1.5 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.1 0.1 1.6e-14 2.1e-10 12 62 .. 136 185 .. 130 202 .. 0.89 2 ! 9.8 0.0 6.5e-05 0.82 157 189 .] 205 237 .. 199 237 .. 0.94 Alignments for each domain: == domain 1 score: 41.1 bits; conditional E-value: 1.6e-14 Proteasome 12 gkdgvvlaadkratagskllskdtveKifkiddhigvafaGlaaDartlvd 62 ++dgv+l+ad+rat+ ++ ++++++Ki+ i ++i+++ a aaD++++ + FUN_002330-T1 136 FQDGVILGADTRATEDTIV-ADKNCSKIHYIAPNIYCCGACIAADTEYVSS 185 68************76666.6666**********************99875 PP == domain 2 score: 9.8 bits; conditional E-value: 6.5e-05 Proteasome 157 ltleeavelakkalkealerdklsgknievavi 189 l+ +ea++l+++a+ + + +d sg+ +++++i FUN_002330-T1 205 LNYDEAKKLVRDAIAAGIFNDLGSGSDVDLCII 237 6789**************************997 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 1.3 1.5e-09 1.9e-05 1 18 [. 251 268 .. 251 269 .] 0.96 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.5e-09 Pr_beta_C 1 PNergeRqgsYkfkrGTT 18 +N +g Rqg+Y +krGTT FUN_002330-T1 251 ANDKGVRQGRYSYKRGTT 268 8***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (269 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 517 (0.0202388); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.37s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 2659.27 // Query: FUN_002331-T1 [L=1223] Description: FUN_002331 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-152 496.8 29.0 1.4e-17 64.1 0.1 11.1 10 TPR_12 Tetratricopeptide repeat 5.2e-135 428.7 27.1 6.2e-07 29.5 0.0 19.6 19 TPR_7 Tetratricopeptide repeat 2.4e-127 410.6 78.3 1.8e-07 31.1 0.1 20.0 20 TPR_1 Tetratricopeptide repeat 3.8e-94 301.4 68.5 9.6e-07 29.0 0.1 19.6 19 TPR_8 Tetratricopeptide repeat 4e-89 290.9 17.9 7e-05 23.2 0.0 19.2 19 TPR_10 Tetratricopeptide repeat 9.5e-64 206.8 67.1 0.00053 20.4 0.0 19.9 20 TPR_2 Tetratricopeptide repeat 9.3e-51 173.4 0.0 1.4e-50 172.9 0.0 1.2 1 CHAT CHAT domain 8.1e-32 106.9 21.8 2.1 9.8 0.0 18.8 18 TPR_14 Tetratricopeptide repeat 1.8e-25 89.3 18.3 0.089 13.4 0.0 14.1 13 Rapsyn_N Rapsyn N-terminal myristoylation a 9e-24 84.9 0.5 0.00018 21.6 0.0 5.7 8 SNAP Soluble NSF attachment protein, SN 7.3e-18 64.4 21.3 5.9 8.3 0.0 17.0 16 TPR_6 Tetratricopeptide repeat 7.9e-18 65.3 0.0 0.0016 18.3 0.0 6.1 7 TPR_MalT MalT-like TPR region 3.8e-14 52.2 41.1 2.3 9.2 0.0 18.0 18 TPR_17 Tetratricopeptide repeat 6.8e-14 52.4 25.7 2.5 8.2 0.0 15.5 17 RPN7 26S proteasome subunit RPN7 1.2e-12 48.2 0.0 0.79 9.6 0.0 7.9 8 TPR_NPHP3 Nephrocystin-3 TPR domain 2.4e-12 47.5 30.8 0.42 11.6 0.0 14.3 15 TPR_16 Tetratricopeptide repeat 1.3e-09 38.4 1.3 39 4.0 0.0 11.8 15 TPR_15 Tetratricopeptide repeat 1.4e-09 38.3 12.3 1.9 9.0 0.0 12.5 14 TPR_9 Tetratricopeptide repeat 2.5e-09 37.6 0.0 1.6e+02 3.0 0.0 11.7 12 DUF2977 Protein of unknown function (DUF29 7.3e-09 36.3 12.8 1.3 9.9 0.0 10.7 13 TPR_19 Tetratricopeptide repeat 7.4e-09 35.7 10.0 41 4.4 0.0 13.2 14 DUF7542 Family of unknown function (DUF754 2.2e-08 34.3 29.0 8.3 7.4 0.0 15.0 14 PPR PPR repeat 5.7e-07 30.0 0.1 2e+02 2.6 0.0 10.7 14 CODH_A_N Carbon monoxide dehydrogenase subu 1.4e-05 25.7 0.2 84 3.9 0.0 9.8 12 DUF7018 Domain of unknown function (DUF701 1.5e-05 25.8 14.9 24 5.9 0.1 11.0 14 Bleomycin_resist_prot_dom Bleomycin resistance protein domai 0.00011 22.6 23.4 0.86 10.0 0.1 10.4 12 DUF3856 Domain of Unknown Function (DUF385 0.00015 22.5 22.4 36 5.1 0.0 12.6 13 ARM_TT21_4th Tetratricopeptide repeat protein 2 0.00025 21.2 61.1 4 7.7 0.0 17.4 18 TPR_11 TPR repeat 0.00033 19.9 5.2 15 4.5 0.0 6.4 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 0.00046 21.0 10.1 1.9e+02 3.6 0.0 11.0 8 TPR_4 Tetratricopeptide repeat 0.00059 19.9 0.2 86 3.0 0.0 7.6 10 DUF6377 Domain of unknown function (DUF637 0.00091 19.9 8.0 79 4.0 0.0 8.6 9 GGDEF_2 GGDEF-like domain ------ inclusion threshold ------ 0.023 15.2 2.5 1e+02 3.4 0.0 5.8 5 DUF386 YhcH/YjgK/YiaL 0.11 13.1 0.0 1.5e+02 2.9 0.0 5.3 6 DUF6225 Family of unknown function (DUF622 0.12 13.2 0.1 45 4.8 0.0 4.8 4 DHR-2_Lobe_A DHR-2, Lobe A 0.14 13.2 0.0 2.6e+02 2.6 0.0 5.1 5 Spectrin Spectrin repeat 0.18 12.1 13.0 34 4.8 0.0 8.7 12 Urocanase_N Urocanase N-terminal domain 0.23 10.6 0.0 35 3.4 0.0 3.5 4 Transferase Transferase family 0.41 11.3 13.4 43 4.8 0.0 8.0 8 MIT MIT (microtubule interacting and t 0.46 11.2 8.3 43 4.9 0.0 5.7 4 TPR_3 Tetratricopeptide repeat 1.1 9.9 8.5 88 3.8 0.0 6.9 7 FbpC_C_terminal FbpC C-terminal regulatory nucleot 3.9 7.4 4.2 82 3.1 0.1 4.7 5 COP9_hel_rpt COP9 signalosome complex subunit 3 Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.8 0.1 2.9e-15 1.8e-12 15 75 .. 22 80 .. 14 82 .. 0.94 2 ! 53.1 0.1 6.5e-17 4e-14 4 75 .. 91 160 .. 85 162 .. 0.96 3 ! 48.9 0.0 1.3e-15 7.9e-13 4 75 .. 171 240 .. 168 242 .. 0.96 4 ! 60.8 0.2 2.4e-19 1.5e-16 4 76 .. 251 321 .. 248 322 .. 0.96 5 ! 60.3 0.1 3.5e-19 2.1e-16 4 75 .. 331 400 .. 328 402 .. 0.96 6 ! 52.0 0.2 1.3e-16 8.2e-14 4 76 .. 411 481 .. 408 482 .. 0.96 7 ! 53.6 0.1 4.5e-17 2.8e-14 4 75 .. 491 560 .. 488 562 .. 0.96 8 ! 64.1 0.1 2.3e-20 1.4e-17 4 76 .. 571 641 .. 568 642 .. 0.95 9 ! 30.4 0.0 7.9e-10 4.8e-07 26 75 .. 633 680 .. 632 682 .. 0.96 10 ! 47.7 0.0 3e-15 1.9e-12 4 75 .. 691 760 .. 688 762 .. 0.95 Alignments for each domain: == domain 1 score: 47.8 bits; conditional E-value: 2.9e-15 TPR_12 15 rlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 lg++ +A+e++e+ l +a+++ +d+ ++ +a+ Lg +y+ lgd+++A+e++e+ leia FUN_002331-T1 22 TLGDFRKAIEYHERHLKVAREV--GDRVGEGNAYGSLGSAYRSLGDFRKAIEYHEKHLEIA 80 58********************..9**********************************98 PP == domain 2 score: 53.1 bits; conditional E-value: 6.5e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++ l+++++A+e++ek le++ ++ +++ ++ a+r Lg++y+ lgd+++A e++++ leia FUN_002331-T1 91 NAYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEV--GNRVGEGSAYRSLGIAYQSLGDFRKASEYHKKHLEIA 160 7999*****************************..99*********************************98 PP == domain 3 score: 48.9 bits; conditional E-value: 1.3e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ n++++++ g++ +A+e++ek le+a ++ +++ ++ +a+ nLg +y l d+++A+e++e+ lei FUN_002331-T1 171 RAYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEV--GNRVGEGNAYGNLGNAYNSLVDFQKAIECHEKHLEIS 240 7999*****************************..99*********************************95 PP == domain 4 score: 60.8 bits; conditional E-value: 2.4e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +a+ +l++++r lg++ +A+e++ek le+a ++ +++ ++ a+ n g++y+ lgd+++A+e++e++lei + FUN_002331-T1 251 SAYGGLGNAYRSLGDLRKAIEYHEKHLEIAIEV--GHRAGQGMAYGNFGTVYQSLGDFRKAIEYYEKCLEITK 321 68999****************************..9999*******************************987 PP == domain 5 score: 60.3 bits; conditional E-value: 3.5e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +++ nl+++++ lg++ +A+e++ek le+a ++ +d+ ++ +a+ +Lg +y+ lgd+++A+e++e+ leia FUN_002331-T1 331 SVYGNLGNAYWSLGDLRKAIEYHEKHLEIAIEV--GDRVGEGIAYGGLGNAYQSLGDFRKAIEYHEKHLEIA 400 6899*****************************..9**********************************98 PP == domain 6 score: 52.0 bits; conditional E-value: 1.3e-16 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +a+ nl+++++ lg + +A+e+lek+le a ++ ++++++ ++ nLg +y lgd+++A++++e++lei + FUN_002331-T1 411 SAYGNLGNAYQSLGYFRKAIEYLEKSLETAIEV--GNRDGEGRTCANLGNAYDSLGDLRKAIDYHEKCLEITK 481 7999*****************************..88999******************************987 PP == domain 7 score: 53.6 bits; conditional E-value: 4.5e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++ lg++ +A++++ek le+a ++ d+ ++ a+ Lg +y+ lgd+++A+e++e++lei FUN_002331-T1 491 RAYGNLGNAYKSLGDFRKAIKYHEKRLEIAIEI--SDRIGEGKAYGSLGNAYRSLGDFRKAIEYHEKCLEIS 560 7999*****************************..***********************************96 PP == domain 8 score: 64.1 bits; conditional E-value: 2.3e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +a+ +l+++++ lg++ +A+e++ek+le+ +++ +d++++ +++ nLg +y lgd+++A+ le++lei + FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKAIEYHEKCLEITKEV--GDRDGEGRTYGNLGSAYDSLGDHRKAIYSLEKCLEITK 641 79999****************************..89999******************************987 PP == domain 9 score: 30.4 bits; conditional E-value: 7.9e-10 TPR_12 26 lekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 lek+le+ +++ +d+ ++ a+ Lg +y lgd+++A+e++e+ leia FUN_002331-T1 633 LEKCLEITKEV--GDRVGEGSAYGILGNAYDSLGDHRKAIEYHEKRLEIA 680 79*********..99*********************************98 PP == domain 10 score: 47.7 bits; conditional E-value: 3e-15 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+ v++ lg++ +A+e++ek+le+ ++ +++ ++ +++n+g+ y+ lg++e Al+ + a++++ FUN_002331-T1 691 NAYGNLGYVYQSLGDFRKAIEYHEKCLEITIEV--GNRAAEGMSHHNIGQGYFSLGQFENALDKFDSAVKVF 760 799******************************..99****************************9999876 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 4.7e-05 0.029 12 35 .. 23 46 .. 20 47 .. 0.93 2 ! 29.1 0.0 1.3e-09 8.2e-07 1 35 [. 52 86 .. 52 87 .. 0.95 3 ! 24.5 0.0 4e-08 2.4e-05 1 35 [. 92 126 .. 92 127 .. 0.92 4 ! 20.0 0.1 1.1e-06 0.00069 1 35 [. 132 166 .. 132 167 .. 0.93 5 ! 17.5 0.0 7.1e-06 0.0043 1 35 [. 172 206 .. 172 207 .. 0.91 6 ! 15.7 0.0 2.7e-05 0.016 1 35 [. 212 246 .. 212 247 .. 0.92 7 ! 25.9 0.1 1.5e-08 8.8e-06 1 35 [. 252 286 .. 252 287 .. 0.93 8 ! 24.8 0.0 3.3e-08 2e-05 2 35 .. 293 326 .. 292 327 .. 0.92 9 ! 25.6 0.0 1.8e-08 1.1e-05 2 35 .. 333 366 .. 332 367 .. 0.94 10 ! 27.4 0.0 4.8e-09 2.9e-06 1 35 [. 372 406 .. 372 407 .. 0.94 11 ! 21.7 0.1 3.1e-07 0.00019 1 35 [. 412 446 .. 412 447 .. 0.92 12 ! 29.5 0.0 1e-09 6.2e-07 1 35 [. 452 486 .. 452 487 .. 0.97 13 ! 24.9 0.0 3e-08 1.8e-05 1 34 [. 492 525 .. 492 527 .. 0.90 14 ! 27.7 0.0 3.8e-09 2.3e-06 1 35 [. 532 566 .. 532 567 .. 0.94 15 ! 27.8 0.0 3.5e-09 2.1e-06 1 35 [. 572 606 .. 572 607 .. 0.95 16 ! 19.9 0.0 1.2e-06 0.00075 1 35 [. 612 646 .. 612 647 .. 0.95 17 ! 21.3 0.1 4.3e-07 0.00026 1 35 [. 652 686 .. 652 687 .. 0.90 18 ! 25.4 0.0 2.2e-08 1.3e-05 1 35 [. 692 726 .. 692 727 .. 0.93 19 ? 3.5 0.0 0.22 1.3e+02 1 24 [. 732 755 .. 732 759 .. 0.89 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 4.7e-05 TPR_7 12 lGdydeAirlyerlLalakdpedr 35 lGd+++Ai+++er+L +a++ +dr FUN_002331-T1 23 LGDFRKAIEYHERHLKVAREVGDR 46 7********************998 PP == domain 2 score: 29.1 bits; conditional E-value: 1.3e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + +dr FUN_002331-T1 52 AYGSLGSAYRSLGDFRKAIEYHEKHLEIAIEVGDR 86 7899*************************999997 PP == domain 3 score: 24.5 bits; conditional E-value: 4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +l d+++Ai+++e++L+++ + ++r FUN_002331-T1 92 AYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEVGNR 126 789************************99887776 PP == domain 4 score: 20.0 bits; conditional E-value: 1.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+ +y++lGd+++A ++++++L++a + +dr FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEYHKKHLEIAIEVGDR 166 6779*************************999997 PP == domain 5 score: 17.5 bits; conditional E-value: 7.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++++++++ + Gd+++Ai+++e+ L++a + ++r FUN_002331-T1 172 AYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEVGNR 206 789*********************99999887776 PP == domain 6 score: 15.7 bits; conditional E-value: 2.7e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +l d+++Ai+++e++L+++ + ++r FUN_002331-T1 212 AYGNLGNAYNSLVDFQKAIECHEKHLEISIEVGNR 246 789************************99877765 PP == domain 7 score: 25.9 bits; conditional E-value: 1.5e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++ L+++yr+lGd ++Ai+++e++L++a + ++r FUN_002331-T1 252 AYGGLGNAYRSLGDLRKAIEYHEKHLEIAIEVGHR 286 6789*************************999887 PP == domain 8 score: 24.8 bits; conditional E-value: 3.3e-08 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++ + +y++lGd+++Ai++ye++L+++k+ +dr FUN_002331-T1 293 YGNFGTVYQSLGDFRKAIEYYEKCLEITKEVGDR 326 6677899************************998 PP == domain 9 score: 25.6 bits; conditional E-value: 1.8e-08 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L+++y +lGd ++Ai+++e++L++a + +dr FUN_002331-T1 333 YGNLGNAYWSLGDLRKAIEYHEKHLEIAIEVGDR 366 589*************************999997 PP == domain 10 score: 27.4 bits; conditional E-value: 4.8e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++ L+++y++lGd+++Ai+++e++L++a + +dr FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIEYHEKHLEIAIEVGDR 406 6789*************************999997 PP == domain 11 score: 21.7 bits; conditional E-value: 3.1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lG +++Ai+++e+ L++a + ++r FUN_002331-T1 412 AYGNLGNAYQSLGYFRKAIEYLEKSLETAIEVGNR 446 789***********************999887765 PP == domain 12 score: 29.5 bits; conditional E-value: 1e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 ++++L+++y +lGd ++Ai+++e++L+++k+ +dr FUN_002331-T1 452 TCANLGNAYDSLGDLRKAIDYHEKCLEITKEVGDR 486 79******************************997 PP == domain 13 score: 24.9 bits; conditional E-value: 3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L+++y +lGd+++Ai+++e+ L++a + +d FUN_002331-T1 492 AYGNLGNAYKSLGDFRKAIKYHEKRLEIAIEISD 525 789***********************99876665 PP == domain 14 score: 27.7 bits; conditional E-value: 3.8e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L+++ + +dr FUN_002331-T1 532 AYGSLGNAYRSLGDFRKAIEYHEKCLEISIEVGDR 566 7899************************9998887 PP == domain 15 score: 27.8 bits; conditional E-value: 3.5e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++ L+++y++lGd ++Ai+++e++L+++k+ +dr FUN_002331-T1 572 AYGGLGNAYQSLGDHRKAIEYHEKCLEITKEVGDR 606 6789****************************998 PP == domain 16 score: 19.9 bits; conditional E-value: 1.2e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 ++++L+++y +lGd ++Ai +e++L+++k+ +dr FUN_002331-T1 612 TYGNLGSAYDSLGDHRKAIYSLEKCLEITKEVGDR 646 578*****************************998 PP == domain 17 score: 21.3 bits; conditional E-value: 4.3e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++ L+++y +lGd ++Ai+++e+ L++a + dr FUN_002331-T1 652 AYGILGNAYDSLGDHRKAIEYHEKRLEIAIEVDDR 686 6778***********************99887776 PP == domain 18 score: 25.4 bits; conditional E-value: 2.2e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L+++ + ++r FUN_002331-T1 692 AYGNLGYVYQSLGDFRKAIEYHEKCLEITIEVGNR 726 789*************************9988887 PP == domain 19 score: 3.5 bits; conditional E-value: 0.22 TPR_7 1 aLsaLariyrklGdydeAirlyer 24 +++++++ y +lG++++A++ ++ FUN_002331-T1 732 SHHNIGQGYFSLGQFENALDKFDS 755 5899****************9987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.4 0.0 0.0095 5.8 14 31 .. 23 40 .. 21 42 .. 0.89 2 ! 24.5 0.1 3.6e-08 2.2e-05 2 30 .. 51 79 .. 50 80 .. 0.95 3 ! 27.3 0.4 4.9e-09 3e-06 2 30 .. 91 119 .. 90 119 .. 0.96 4 ! 19.3 0.1 1.7e-06 0.001 3 30 .. 132 159 .. 130 160 .. 0.95 5 ! 25.0 0.1 2.6e-08 1.6e-05 2 30 .. 171 199 .. 170 200 .. 0.95 6 ! 25.3 0.1 2.1e-08 1.3e-05 2 30 .. 211 239 .. 210 240 .. 0.96 7 ! 25.9 0.2 1.3e-08 8.2e-06 3 30 .. 252 279 .. 250 280 .. 0.95 8 ! 26.1 0.1 1.2e-08 7.4e-06 3 30 .. 292 319 .. 291 320 .. 0.93 9 ! 26.4 0.2 9.7e-09 5.9e-06 3 30 .. 332 359 .. 331 360 .. 0.95 10 ! 27.5 0.3 4.2e-09 2.5e-06 3 30 .. 372 399 .. 370 400 .. 0.95 11 ! 22.5 0.5 1.6e-07 9.8e-05 3 29 .. 412 438 .. 410 440 .. 0.95 12 ! 26.4 0.1 9.2e-09 5.6e-06 3 30 .. 452 479 .. 450 480 .. 0.94 13 ! 25.6 0.5 1.7e-08 1e-05 2 26 .. 491 515 .. 490 520 .. 0.91 14 ! 31.1 0.1 3e-10 1.8e-07 2 30 .. 531 559 .. 530 560 .. 0.96 15 ! 29.8 0.2 7.7e-10 4.7e-07 2 30 .. 571 599 .. 570 600 .. 0.97 16 ! 22.5 0.0 1.6e-07 9.8e-05 2 30 .. 611 639 .. 610 640 .. 0.96 17 ! 18.6 0.1 2.8e-06 0.0017 3 26 .. 652 675 .. 650 680 .. 0.90 18 ! 30.1 0.5 6.2e-10 3.8e-07 2 30 .. 691 719 .. 690 719 .. 0.96 19 ! 13.6 0.0 0.0001 0.064 4 29 .. 733 758 .. 731 761 .. 0.91 20 ? -1.1 0.0 4.6 2.8e+03 11 23 .. 792 804 .. 791 807 .. 0.83 Alignments for each domain: == domain 1 score: 7.4 bits; conditional E-value: 0.0095 TPR_1 14 lgkydeAleyyekALeln 31 lg++ +A+ey e+ L++ FUN_002331-T1 23 LGDFRKAIEYHERHLKVA 40 8************99976 PP == domain 2 score: 24.5 bits; conditional E-value: 3.6e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lG ay++lg++ +A+ey ek Le+ FUN_002331-T1 51 NAYGSLGSAYRSLGDFRKAIEYHEKHLEI 79 59*************************98 PP == domain 3 score: 27.3 bits; conditional E-value: 4.9e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay +l ++++A+ey ek Le+ FUN_002331-T1 91 NAYGNLGNAYDSLDDFQKAIEYHEKHLEI 119 69************************997 PP == domain 4 score: 19.3 bits; conditional E-value: 1.7e-06 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lG ay++lg++ +A ey +k Le+ FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEYHKKHLEI 159 8999**********************98 PP == domain 5 score: 25.0 bits; conditional E-value: 2.6e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ n+Gna+++ g++ +A+ey ek Le+ FUN_002331-T1 171 RAYGNIGNAHYSVGDFRKAIEYHEKNLEI 199 79************************998 PP == domain 6 score: 25.3 bits; conditional E-value: 2.1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay +l ++++A+e+ ek Le+ FUN_002331-T1 211 NAYGNLGNAYNSLVDFQKAIECHEKHLEI 239 69*************************98 PP == domain 7 score: 25.9 bits; conditional E-value: 1.3e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ +lGnay++lg++ +A+ey ek Le+ FUN_002331-T1 252 AYGGLGNAYRSLGDLRKAIEYHEKHLEI 279 9*************************98 PP == domain 8 score: 26.1 bits; conditional E-value: 1.2e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ n G +y++lg++ +A+eyyek+Le+ FUN_002331-T1 292 AYGNFGTVYQSLGDFRKAIEYYEKCLEI 319 6777799*******************97 PP == domain 9 score: 26.4 bits; conditional E-value: 9.7e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 ++ nlGnay +lg++ +A+ey ek Le+ FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEYHEKHLEI 359 699***********************98 PP == domain 10 score: 27.5 bits; conditional E-value: 4.2e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ +lGnay++lg++ +A+ey ek Le+ FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIEYHEKHLEI 399 99************************98 PP == domain 11 score: 22.5 bits; conditional E-value: 1.6e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALe 29 a+ nlGnay++lg + +A+ey ek Le FUN_002331-T1 412 AYGNLGNAYQSLGYFRKAIEYLEKSLE 438 9************************98 PP == domain 12 score: 26.4 bits; conditional E-value: 9.2e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 ++ nlGnay +lg++ +A++y ek+Le+ FUN_002331-T1 452 TCANLGNAYDSLGDLRKAIDYHEKCLEI 479 678***********************97 PP == domain 13 score: 25.6 bits; conditional E-value: 1.7e-08 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ nlGnay +lg++ +A++y ek FUN_002331-T1 491 RAYGNLGNAYKSLGDFRKAIKYHEK 515 79********************998 PP == domain 14 score: 31.1 bits; conditional E-value: 3e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 ka+ lGnay++lg++ +A+ey ek+Le+ FUN_002331-T1 531 KAYGSLGNAYRSLGDFRKAIEYHEKCLEI 559 79**************************8 PP == domain 15 score: 29.8 bits; conditional E-value: 7.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ +lGnay++lg++ +A+ey ek+Le+ FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKAIEYHEKCLEI 599 69*************************97 PP == domain 16 score: 22.5 bits; conditional E-value: 1.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +++ nlG ay +lg++ +A+ ek+Le+ FUN_002331-T1 611 RTYGNLGSAYDSLGDHRKAIYSLEKCLEI 639 689************************97 PP == domain 17 score: 18.6 bits; conditional E-value: 2.8e-06 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ lGnay +lg++ +A+ey ek FUN_002331-T1 652 AYGILGNAYDSLGDHRKAIEYHEK 675 8999*****************998 PP == domain 18 score: 30.1 bits; conditional E-value: 6.2e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG++y++lg++ +A+ey ek+Le+ FUN_002331-T1 691 NAYGNLGYVYQSLGDFRKAIEYHEKCLEI 719 69*************************97 PP == domain 19 score: 13.6 bits; conditional E-value: 0.0001 TPR_1 4 lynlGnayfklgkydeAleyyekALe 29 + n+G+ yf+lg+++ Al+ ++ A++ FUN_002331-T1 733 HHNIGQGYFSLGQFENALDKFDSAVK 758 78*****************9999987 PP == domain 20 score: -1.1 bits; conditional E-value: 4.6 TPR_1 11 yfklgkydeAley 23 ++k gk deAl + FUN_002331-T1 792 LLKIGKIDEALFA 804 6899******965 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 1.2 7.6e+02 13 26 .. 22 35 .. 21 42 .. 0.79 2 ! 17.4 0.1 8.2e-06 0.005 3 30 .. 52 79 .. 50 80 .. 0.90 3 ! 17.0 0.2 1.1e-05 0.0065 3 28 .. 92 117 .. 90 119 .. 0.89 4 ? 7.2 0.2 0.015 9.1 6 30 .. 135 159 .. 131 160 .. 0.83 5 ! 12.3 0.1 0.00035 0.21 2 30 .. 171 199 .. 170 200 .. 0.90 6 ! 11.2 0.1 0.00082 0.5 3 30 .. 212 239 .. 210 240 .. 0.89 7 ! 16.2 0.1 2e-05 0.012 2 30 .. 251 279 .. 250 280 .. 0.90 8 ! 29.0 0.1 1.6e-09 9.6e-07 3 31 .. 292 320 .. 292 322 .. 0.94 9 ! 20.1 0.1 1.1e-06 0.00068 3 30 .. 332 359 .. 330 360 .. 0.90 10 ! 15.6 0.2 3.1e-05 0.019 3 30 .. 372 399 .. 371 400 .. 0.90 11 ! 25.0 0.5 2.9e-08 1.8e-05 2 29 .. 411 438 .. 410 440 .. 0.94 12 ! 22.9 0.1 1.4e-07 8.8e-05 2 31 .. 451 480 .. 450 482 .. 0.93 13 ! 20.4 0.2 9.2e-07 0.00056 2 30 .. 491 519 .. 490 520 .. 0.89 14 ! 24.8 0.1 3.4e-08 2.1e-05 2 30 .. 531 559 .. 530 560 .. 0.95 15 ! 25.3 0.1 2.5e-08 1.5e-05 2 31 .. 571 600 .. 570 602 .. 0.94 16 ! 24.3 0.0 5e-08 3.1e-05 2 31 .. 611 640 .. 610 642 .. 0.94 17 ! 16.4 0.1 1.7e-05 0.01 2 30 .. 651 679 .. 650 680 .. 0.88 18 ! 26.3 0.1 1.2e-08 7.2e-06 3 30 .. 692 719 .. 690 720 .. 0.95 19 ? 5.7 0.0 0.047 29 4 22 .. 733 751 .. 732 762 .. 0.74 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 1.2 TPR_8 13 klgdyeeAkeyyek 26 +lgd+ +A+ey e+ FUN_002331-T1 22 TLGDFRKAIEYHER 35 79********9665 PP == domain 2 score: 17.4 bits; conditional E-value: 8.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002331-T1 52 AYGSLGSAYRSLGDFRKAIEYHEKHLEI 79 89*******************9987776 PP == domain 3 score: 17.0 bits; conditional E-value: 1.1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekal 28 ay nlG++y +l d+++A+ey ek l FUN_002331-T1 92 AYGNLGNAYDSLDDFQKAIEYHEKHL 117 9********************88755 PP == domain 4 score: 7.2 bits; conditional E-value: 0.015 TPR_8 6 nlGliylklgdyeeAkeyyekalel 30 lG +y++lgd+ +A ey +k le+ FUN_002331-T1 135 SLGIAYQSLGDFRKASEYHKKHLEI 159 6899*************97776665 PP == domain 5 score: 12.3 bits; conditional E-value: 0.00035 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay n+G+++ + gd+ +A+ey ek le+ FUN_002331-T1 171 RAYGNIGNAHYSVGDFRKAIEYHEKNLEI 199 89********************8886665 PP == domain 6 score: 11.2 bits; conditional E-value: 0.00082 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y +l d+++A+e+ ek le+ FUN_002331-T1 212 AYGNLGNAYNSLVDFQKAIECHEKHLEI 239 8*******************98887766 PP == domain 7 score: 16.2 bits; conditional E-value: 2e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ey ek le+ FUN_002331-T1 251 SAYGGLGNAYRSLGDLRKAIEYHEKHLEI 279 5899******************9987776 PP == domain 8 score: 29.0 bits; conditional E-value: 1.6e-09 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay n G +y++lgd+ +A+eyyek+le+ FUN_002331-T1 292 AYGNFGTVYQSLGDFRKAIEYYEKCLEIT 320 799************************96 PP == domain 9 score: 20.1 bits; conditional E-value: 1.1e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 +y nlG++y++lgd+ +A+ey ek le+ FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEYHEKHLEI 359 8********************9987776 PP == domain 10 score: 15.6 bits; conditional E-value: 3.1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIEYHEKHLEI 399 7999*****************9987776 PP == domain 11 score: 25.0 bits; conditional E-value: 2.9e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekale 29 +ay nlG++y++lg++ +A+ey+ek+le FUN_002331-T1 411 SAYGNLGNAYQSLGYFRKAIEYLEKSLE 438 59************************98 PP == domain 12 score: 22.9 bits; conditional E-value: 1.4e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +++ nlG++y +lgd+ +A+ y ek+le+ FUN_002331-T1 451 RTCANLGNAYDSLGDLRKAIDYHEKCLEIT 480 6899************************96 PP == domain 13 score: 20.4 bits; conditional E-value: 9.2e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd+ +A++y ek le+ FUN_002331-T1 491 RAYGNLGNAYKSLGDFRKAIKYHEKRLEI 519 89********************8886665 PP == domain 14 score: 24.8 bits; conditional E-value: 3.4e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+ +A+ey ek+le+ FUN_002331-T1 531 KAYGSLGNAYRSLGDFRKAIEYHEKCLEI 559 69**************************9 PP == domain 15 score: 25.3 bits; conditional E-value: 2.5e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay lG++y++lgd+ +A+ey ek+le+ FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKAIEYHEKCLEIT 600 79**************************96 PP == domain 16 score: 24.3 bits; conditional E-value: 5e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 ++y nlG++y +lgd+ +A+ ++ek+le+ FUN_002331-T1 611 RTYGNLGSAYDSLGDHRKAIYSLEKCLEIT 640 78**************************96 PP == domain 17 score: 16.4 bits; conditional E-value: 1.7e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y +lgd+ +A+ey ek le+ FUN_002331-T1 651 SAYGILGNAYDSLGDHRKAIEYHEKRLEI 679 5899******************8886665 PP == domain 18 score: 26.3 bits; conditional E-value: 1.2e-08 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek+le+ FUN_002331-T1 692 AYGNLGYVYQSLGDFRKAIEYHEKCLEI 719 9*************************98 PP == domain 19 score: 5.7 bits; conditional E-value: 0.047 TPR_8 4 yynlGliylklgdyeeAke 22 ++n+G+ y +lg++e+A FUN_002331-T1 733 HHNIGQGYFSLGQFENALD 751 6889999999999999865 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 1.1 6.9e+02 15 34 .. 23 42 .. 17 43 .. 0.66 2 ! 13.3 0.0 0.00015 0.093 4 34 .. 52 82 .. 50 83 .. 0.91 3 ! 12.7 0.0 0.00023 0.14 4 31 .. 92 119 .. 90 123 .. 0.80 4 ! 11.7 0.0 0.00047 0.28 3 34 .. 131 162 .. 130 163 .. 0.91 5 ! 16.5 0.0 1.5e-05 0.009 4 35 .. 172 203 .. 170 203 .. 0.93 6 ! 9.4 0.0 0.0026 1.6 9 36 .. 210 237 .. 210 243 .. 0.73 7 ! 13.4 0.0 0.00014 0.085 3 34 .. 251 282 .. 250 283 .. 0.91 8 ! 22.6 0.0 1.7e-07 0.0001 4 35 .. 292 323 .. 290 323 .. 0.95 9 ! 16.1 0.0 1.9e-05 0.011 4 35 .. 332 363 .. 330 363 .. 0.91 10 ! 13.0 0.0 0.00019 0.11 4 35 .. 372 403 .. 371 403 .. 0.90 11 ! 21.0 0.1 5.6e-07 0.00034 3 35 .. 411 443 .. 410 447 .. 0.94 12 ! 21.3 0.0 4.5e-07 0.00028 4 35 .. 452 483 .. 450 483 .. 0.95 13 ! 15.1 0.0 3.9e-05 0.024 4 34 .. 492 522 .. 490 525 .. 0.90 14 ! 21.3 0.0 4.3e-07 0.00026 4 35 .. 532 563 .. 531 563 .. 0.93 15 ! 21.7 0.0 3.3e-07 0.0002 4 35 .. 572 603 .. 570 603 .. 0.94 16 ! 15.7 0.0 2.6e-05 0.016 4 35 .. 612 643 .. 610 643 .. 0.96 17 ! 8.2 0.0 0.0061 3.7 3 34 .. 651 682 .. 650 683 .. 0.87 18 ! 23.2 0.0 1.2e-07 7e-05 4 35 .. 692 723 .. 690 723 .. 0.94 19 ? 2.5 0.0 0.38 2.3e+02 6 23 .. 734 751 .. 731 760 .. 0.87 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.1 TPR_10 15 qgryeeAeelleealairer 34 +g++ A e++e+ l+++++ FUN_002331-T1 23 LGDFRKAIEYHERHLKVARE 42 67777777777776666666 PP == domain 2 score: 13.3 bits; conditional E-value: 0.00015 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+ a+r++g++ A e++e+ l+i+ + FUN_002331-T1 52 AYGSLGSAYRSLGDFRKAIEYHEKHLEIAIE 82 7999********************9999876 PP == domain 3 score: 12.7 bits; conditional E-value: 0.00023 TPR_10 4 slnnLanalraqgryeeAeelleealai 31 ++ nL+na+ ++ +++ A e++e+ l+i FUN_002331-T1 92 AYGNLGNAYDSLDDFQKAIEYHEKHLEI 119 7889999999999999999999986665 PP == domain 4 score: 11.7 bits; conditional E-value: 0.00047 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ L+ a++++g++ A e++++ l+i+ + FUN_002331-T1 131 SAYRSLGIAYQSLGDFRKASEYHKKHLEIAIE 162 6899********************99998876 PP == domain 5 score: 16.5 bits; conditional E-value: 1.5e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ n++na+++ g++ A e++e+ l+i+ +v FUN_002331-T1 172 AYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEV 203 899************************98776 PP == domain 6 score: 9.4 bits; conditional E-value: 0.0026 TPR_10 9 analraqgryeeAeelleealairervl 36 +na+ ++g+ ++ ++++a++++e++l FUN_002331-T1 210 GNAYGNLGNAYNSLVDFQKAIECHEKHL 237 6777777777778888888888887776 PP == domain 7 score: 13.4 bits; conditional E-value: 0.00014 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ L+na+r++g++ A e++e+ l+i+ + FUN_002331-T1 251 SAYGGLGNAYRSLGDLRKAIEYHEKHLEIAIE 282 68999********************9999876 PP == domain 8 score: 22.6 bits; conditional E-value: 1.7e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ n +++++++g++ A e++e++l+i+++v FUN_002331-T1 292 AYGNFGTVYQSLGDFRKAIEYYEKCLEITKEV 323 899**************************997 PP == domain 9 score: 16.1 bits; conditional E-value: 1.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 + nL+na++++g++ A e++e+ l+i+ +v FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEYHEKHLEIAIEV 363 699*********************99998765 PP == domain 10 score: 13.0 bits; conditional E-value: 0.00019 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+ +v FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIEYHEKHLEIAIEV 403 5778********************99998765 PP == domain 11 score: 21.0 bits; conditional E-value: 5.6e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g + A e+le++l+++ +v FUN_002331-T1 411 SAYGNLGNAYQSLGYFRKAIEYLEKSLETAIEV 443 79**************************98776 PP == domain 12 score: 21.3 bits; conditional E-value: 4.5e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+ ++g++ A +++e++l+i+++v FUN_002331-T1 452 TCANLGNAYDSLGDLRKAIDYHEKCLEITKEV 483 789**************************997 PP == domain 13 score: 15.1 bits; conditional E-value: 3.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na+ ++g++ A +++e+ l+i+ + FUN_002331-T1 492 AYGNLGNAYKSLGDFRKAIKYHEKRLEIAIE 522 89*********************98888765 PP == domain 14 score: 21.3 bits; conditional E-value: 4.3e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+r++g++ A e++e++l+i +v FUN_002331-T1 532 AYGSLGNAYRSLGDFRKAIEYHEKCLEISIEV 563 7899************************8776 PP == domain 15 score: 21.7 bits; conditional E-value: 3.3e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e++l+i+++v FUN_002331-T1 572 AYGGLGNAYQSLGDHRKAIEYHEKCLEITKEV 603 7889*************************997 PP == domain 16 score: 15.7 bits; conditional E-value: 2.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a+ ++g++ A le++l+i+++v FUN_002331-T1 612 TYGNLGSAYDSLGDHRKAIYSLEKCLEITKEV 643 89***************************997 PP == domain 17 score: 8.2 bits; conditional E-value: 0.0061 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ L+na+ ++g++ A e++e+ l+i+ + FUN_002331-T1 651 SAYGILGNAYDSLGDHRKAIEYHEKRLEIAIE 682 56777*******************98888766 PP == domain 18 score: 23.2 bits; conditional E-value: 1.2e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ +++++g++ A e++e++l+i+ +v FUN_002331-T1 692 AYGNLGYVYQSLGDFRKAIEYHEKCLEITIEV 723 89**************************9876 PP == domain 19 score: 2.5 bits; conditional E-value: 0.38 TPR_10 6 nnLanalraqgryeeAee 23 +n+++ ++++g++e A++ FUN_002331-T1 734 HNIGQGYFSLGQFENALD 751 89************9986 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 3.9 2.3e+03 14 23 .. 23 32 .. 17 35 .. 0.86 2 ! 10.2 0.2 0.0016 1 3 23 .. 52 72 .. 50 80 .. 0.90 3 ! 11.9 0.2 0.00047 0.28 3 23 .. 92 112 .. 90 116 .. 0.90 4 ! 8.5 0.1 0.0058 3.5 3 23 .. 132 152 .. 130 155 .. 0.92 5 ! 10.7 0.1 0.0011 0.67 2 23 .. 171 192 .. 170 199 .. 0.93 6 ? 3.9 0.0 0.17 1.1e+02 8 30 .. 210 232 .. 207 236 .. 0.78 7 ! 11.5 0.3 0.00064 0.39 3 23 .. 252 272 .. 250 280 .. 0.91 8 ! 20.4 0.0 8.6e-07 0.00053 4 31 .. 293 320 .. 291 322 .. 0.89 9 ! 12.7 0.1 0.00025 0.15 3 23 .. 332 352 .. 330 360 .. 0.91 10 ! 12.2 0.2 0.00037 0.22 3 23 .. 372 392 .. 370 400 .. 0.91 11 ! 20.4 0.4 8.9e-07 0.00054 3 29 .. 412 438 .. 410 440 .. 0.94 12 ! 14.9 0.0 5e-05 0.03 3 31 .. 452 480 .. 450 482 .. 0.91 13 ! 13.9 0.3 0.00011 0.065 2 23 .. 491 512 .. 490 518 .. 0.94 14 ! 17.3 0.1 8.3e-06 0.005 2 30 .. 531 559 .. 530 562 .. 0.92 15 ! 16.0 0.1 2.2e-05 0.013 2 31 .. 571 600 .. 570 602 .. 0.92 16 ! 15.5 0.0 3.2e-05 0.019 3 31 .. 612 640 .. 610 642 .. 0.91 17 ! 8.8 0.2 0.0047 2.8 3 23 .. 652 672 .. 650 678 .. 0.91 18 ! 16.7 0.1 1.4e-05 0.0083 3 30 .. 692 719 .. 690 721 .. 0.93 19 ! 14.5 0.0 7e-05 0.042 4 30 .. 733 759 .. 731 763 .. 0.91 20 ? -0.2 0.0 3.5 2.1e+03 10 26 .. 791 807 .. 790 811 .. 0.84 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 3.9 TPR_2 14 lgdyeeAlea 23 lgd+ +A+e+ FUN_002331-T1 23 LGDFRKAIEY 32 7999999997 PP == domain 2 score: 10.2 bits; conditional E-value: 0.0016 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG ay+ lgd+ +A+e+ FUN_002331-T1 52 AYGSLGSAYRSLGDFRKAIEY 72 7888***************98 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00047 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay l d+++A+e+ FUN_002331-T1 92 AYGNLGNAYDSLDDFQKAIEY 112 8999**************998 PP == domain 4 score: 8.5 bits; conditional E-value: 0.0058 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG ay lgd+ +A e+ FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEY 152 8999**************887 PP == domain 5 score: 10.7 bits; conditional E-value: 0.0011 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ n G+a+y gd+ +A+e+ FUN_002331-T1 171 RAYGNIGNAHYSVGDFRKAIEY 192 6899****************98 PP == domain 6 score: 3.9 bits; conditional E-value: 0.17 TPR_2 8 GlayyklgdyeeAleayekAlel 30 G+ay +lg+ l +++kA+e FUN_002331-T1 210 GNAYGNLGNAYNSLVDFQKAIEC 232 88888888888888888888876 PP == domain 7 score: 11.5 bits; conditional E-value: 0.00064 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002331-T1 252 AYGGLGNAYRSLGDLRKAIEY 272 7889***************98 PP == domain 8 score: 20.4 bits; conditional E-value: 8.6e-07 TPR_2 4 lynlGlayyklgdyeeAleayekAleld 31 + n G +y lgd+ +A+e+yek+le+ FUN_002331-T1 293 YGNFGTVYQSLGDFRKAIEYYEKCLEIT 320 667799********************86 PP == domain 9 score: 12.7 bits; conditional E-value: 0.00025 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nlG+ay+ lgd+ +A+e+ FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEY 352 688****************98 PP == domain 10 score: 12.2 bits; conditional E-value: 0.00037 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIEY 392 7889***************98 PP == domain 11 score: 20.4 bits; conditional E-value: 8.9e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAle 29 a+ nlG+ay lg + +A+e++ek+le FUN_002331-T1 412 AYGNLGNAYQSLGYFRKAIEYLEKSLE 438 899**********************98 PP == domain 12 score: 14.9 bits; conditional E-value: 5e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 + nlG+ay lgd+ +A+++ ek+le+ FUN_002331-T1 452 TCANLGNAYDSLGDLRKAIDYHEKCLEIT 480 578***********************986 PP == domain 13 score: 13.9 bits; conditional E-value: 0.00011 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ nlG+ay lgd+ +A+++ FUN_002331-T1 491 RAYGNLGNAYKSLGDFRKAIKY 512 6899****************98 PP == domain 14 score: 17.3 bits; conditional E-value: 8.3e-06 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ lG+ay+ lgd+ +A+e+ ek+le+ FUN_002331-T1 531 KAYGSLGNAYRSLGDFRKAIEYHEKCLEI 559 68889*********************998 PP == domain 15 score: 16.0 bits; conditional E-value: 2.2e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ lG+ay lgd+ +A+e+ ek+le+ FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKAIEYHEKCLEIT 600 58999**********************986 PP == domain 16 score: 15.5 bits; conditional E-value: 3.2e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 + nlG ay lgd+ +A+ +ek+le+ FUN_002331-T1 612 TYGNLGSAYDSLGDHRKAIYSLEKCLEIT 640 6889***********************86 PP == domain 17 score: 8.8 bits; conditional E-value: 0.0047 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002331-T1 652 AYGILGNAYDSLGDHRKAIEY 672 6778***************98 PP == domain 18 score: 16.7 bits; conditional E-value: 1.4e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a+ nlG++y lgd+ +A+e+ ek+le+ FUN_002331-T1 692 AYGNLGYVYQSLGDFRKAIEYHEKCLEI 719 899********************99997 PP == domain 19 score: 14.5 bits; conditional E-value: 7e-05 TPR_2 4 lynlGlayyklgdyeeAleayekAlel 30 ++n G+ y+ lg++e Al+ ++ A++ FUN_002331-T1 733 HHNIGQGYFSLGQFENALDKFDSAVKV 759 89********************99986 PP == domain 20 score: -0.2 bits; conditional E-value: 3.5 TPR_2 10 ayyklgdyeeAleayek 26 +++k g+ +eAl a ++ FUN_002331-T1 791 SLLKIGKIDEALFAADQ 807 68899*******99876 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 172.9 0.0 2.3e-53 1.4e-50 8 291 .] 947 1209 .. 942 1209 .. 0.87 Alignments for each domain: == domain 1 score: 172.9 bits; conditional E-value: 2.3e-53 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ +Lviv dgaL +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ ++ k FUN_002331-T1 947 YDAVIGPIEDLL-GPEDDELVIVSDGALCFIPWAAVIESIR---------IRIVPSLKSyqlISSVPEGYHKKTGA--LLVGNPCTKQ----LK 1024 899****99997.77777*****************988863.........55556654422266666666666666..*******885....47 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvfl.enppersglvLaaensredglLtaeelaelnlsga 191 +++lp +++E++++a++l++ ++l+g++at+ ++++ + ++++++H+a+Hg + ++ l ++ ++ed L++++++ nl+ a FUN_002331-T1 1025 KPLEPLPCAQKEVEMIAAILNT---RPLIGKEATKAEVMKRM-SSVGLIHIAAHGDEVtGQIALSPNLGWTQFPKEEDYILKMSDVQAANLR-A 1113 777*****************88...8***************9.************977344455555555556666****************.* PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 192 elVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhspyyWAa 285 +lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + l+++++ +++ +yWA FUN_002331-T1 1114 RLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATMEFMKRFYQHLKEGKTASAAVHQSMKCLRESEE----FSEMWYWAP 1203 **************************************************************************9999997....556****** PP xxxxxx RF CHAT 286 fvliGd 291 f+liGd FUN_002331-T1 1204 FQLIGD 1209 *****7 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 1.7 1e+03 13 30 .. 22 39 .. 16 44 .. 0.86 2 ? 7.1 0.0 0.026 16 5 29 .. 54 78 .. 51 80 .. 0.86 3 ? 2.8 0.0 0.65 3.9e+02 6 29 .. 95 118 .. 91 120 .. 0.86 4 ? 3.2 0.0 0.45 2.8e+02 3 29 .. 132 158 .. 131 162 .. 0.88 5 ? 0.2 0.0 4.4 2.7e+03 8 25 .. 177 194 .. 171 195 .. 0.84 6 ? 6.7 0.1 0.034 21 6 29 .. 255 278 .. 251 281 .. 0.88 7 ? 8.3 0.0 0.011 6.5 10 30 .. 299 319 .. 293 325 .. 0.88 8 ? 6.5 0.0 0.04 24 7 29 .. 336 358 .. 332 361 .. 0.90 9 ? 5.6 0.0 0.081 49 6 29 .. 375 398 .. 372 400 .. 0.88 10 ? 7.5 0.0 0.018 11 6 30 .. 415 439 .. 411 442 .. 0.89 11 ? 5.7 0.0 0.075 45 7 30 .. 456 479 .. 452 485 .. 0.90 12 ? 6.6 0.1 0.037 23 6 29 .. 495 518 .. 491 520 .. 0.87 13 ! 9.8 0.0 0.0035 2.1 6 29 .. 535 558 .. 531 562 .. 0.90 14 ? 8.0 0.0 0.013 8.1 6 30 .. 575 599 .. 571 605 .. 0.87 15 ? 5.3 0.0 0.095 58 6 29 .. 655 678 .. 651 685 .. 0.89 16 ? 6.4 0.0 0.042 26 6 29 .. 695 718 .. 691 722 .. 0.89 17 ? 4.2 0.0 0.22 1.3e+02 4 25 .. 740 761 .. 734 773 .. 0.62 18 ? 0.5 0.1 3.5 2.1e+03 10 31 .. 791 812 .. 790 825 .. 0.71 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 1.7 TPR_14 13 alGdpdeAlelleralal 30 lGd+ +A+e+ er l+ FUN_002331-T1 22 TLGDFRKAIEYHERHLKV 39 69************9985 PP == domain 2 score: 7.1 bits; conditional E-value: 0.026 TPR_14 5 lalarallalGdpdeAlellerala 29 l+ a++ lGd+ +A+e+ e+ l+ FUN_002331-T1 54 GSLGSAYRSLGDFRKAIEYHEKHLE 78 5699***************998876 PP == domain 3 score: 2.8 bits; conditional E-value: 0.65 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ l+d+++A+e+ e+ l+ FUN_002331-T1 95 NLGNAYDSLDDFQKAIEYHEKHLE 118 6899**************998776 PP == domain 4 score: 3.2 bits; conditional E-value: 0.45 TPR_14 3 awlalarallalGdpdeAlellerala 29 a++ l+ a+ lGd+ +A e+ ++ l+ FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEYHKKHLE 158 78999**************99887765 PP == domain 5 score: 0.2 bits; conditional E-value: 4.4 TPR_14 8 arallalGdpdeAlelle 25 ++a+ Gd+ +A+e+ e FUN_002331-T1 177 GNAHYSVGDFRKAIEYHE 194 78999*********9866 PP == domain 6 score: 6.7 bits; conditional E-value: 0.034 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002331-T1 255 GLGNAYRSLGDLRKAIEYHEKHLE 278 699***************999876 PP == domain 7 score: 8.3 bits; conditional E-value: 0.011 TPR_14 10 allalGdpdeAlelleralal 30 ++ lGd+ +A+e++e++l+ FUN_002331-T1 299 VYQSLGDFRKAIEYYEKCLEI 319 7889**************986 PP == domain 8 score: 6.5 bits; conditional E-value: 0.04 TPR_14 7 larallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002331-T1 336 LGNAYWSLGDLRKAIEYHEKHLE 358 899**************999876 PP == domain 9 score: 5.6 bits; conditional E-value: 0.081 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002331-T1 375 GLGNAYQSLGDFRKAIEYHEKHLE 398 589***************998876 PP == domain 10 score: 7.5 bits; conditional E-value: 0.018 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lG + +A+e+le+ l++ FUN_002331-T1 415 NLGNAYQSLGYFRKAIEYLEKSLET 439 5899****************99875 PP == domain 11 score: 5.7 bits; conditional E-value: 0.075 TPR_14 7 larallalGdpdeAlelleralal 30 l++a+ lGd+ +A+++ e++l+ FUN_002331-T1 456 LGNAYDSLGDLRKAIDYHEKCLEI 479 899******************986 PP == domain 12 score: 6.6 bits; conditional E-value: 0.037 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+++ e+ l+ FUN_002331-T1 495 NLGNAYKSLGDFRKAIKYHEKRLE 518 689***************999887 PP == domain 13 score: 9.8 bits; conditional E-value: 0.0035 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e++l+ FUN_002331-T1 535 SLGNAYRSLGDFRKAIEYHEKCLE 558 699******************998 PP == domain 14 score: 8.0 bits; conditional E-value: 0.013 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e++l+ FUN_002331-T1 575 GLGNAYQSLGDHRKAIEYHEKCLEI 599 699*******************986 PP == domain 15 score: 5.3 bits; conditional E-value: 0.095 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002331-T1 655 ILGNAYDSLGDHRKAIEYHEKRLE 678 699***************999987 PP == domain 16 score: 6.4 bits; conditional E-value: 0.042 TPR_14 6 alarallalGdpdeAlellerala 29 l++++ lGd+ +A+e+ e++l+ FUN_002331-T1 695 NLGYVYQSLGDFRKAIEYHEKCLE 718 68999****************997 PP == domain 17 score: 4.2 bits; conditional E-value: 0.22 TPR_14 4 wlalarallalGdpdeAlelle 25 + l++++ al+++d A+++++ FUN_002331-T1 740 YFSLGQFENALDKFDSAVKVFN 761 3445555555555555555555 PP == domain 18 score: 0.5 bits; conditional E-value: 3.5 TPR_14 10 allalGdpdeAlelleralald 31 ll+ G+ deAl +++++ a+ FUN_002331-T1 791 SLLKIGKIDEALFAADQGRAQT 812 57899************98864 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.0 0.066 40 51 78 .. 18 45 .. 4 47 .. 0.80 2 ! 8.9 0.0 0.0036 2.2 31 78 .. 38 85 .. 36 87 .. 0.90 3 ? 2.5 0.0 0.37 2.2e+02 42 78 .. 132 165 .. 125 167 .. 0.80 4 ! 11.3 0.0 0.00062 0.38 37 76 .. 164 203 .. 160 206 .. 0.92 5 ? 2.0 0.0 0.5 3.1e+02 46 76 .. 253 283 .. 220 287 .. 0.82 6 ! 9.5 0.0 0.0024 1.4 21 78 .. 305 365 .. 296 367 .. 0.79 7 ? 5.7 0.1 0.037 23 47 77 .. 374 404 .. 365 406 .. 0.89 8 ? 4.0 0.0 0.12 76 46 77 .. 413 444 .. 404 447 .. 0.86 9 ! 12.4 0.0 0.00029 0.18 21 78 .. 465 525 .. 457 527 .. 0.91 10 ! 7.6 0.0 0.0091 5.6 38 78 .. 525 565 .. 523 567 .. 0.87 11 ? 6.6 0.0 0.019 12 38 78 .. 565 605 .. 562 607 .. 0.90 12 ! 13.4 0.0 0.00015 0.089 21 79 .. 625 686 .. 617 687 .. 0.83 13 ? 2.6 0.0 0.33 2e+02 43 76 .. 693 723 .. 688 726 .. 0.80 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.066 Rapsyn_N 51 tahsemGkykealefslaqlniaeeled 78 s +G ++ a+e+ l +a+e+ d FUN_002331-T1 18 SDMSTLGDFRKAIEYHERHLKVAREVGD 45 445678*******************865 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0036 Rapsyn_N 31 kvlkktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 kv ++ dr + + G l a+ +G ++ a+e+ + l+ia e+ d FUN_002331-T1 38 KVAREVGDRVGEGNAYGSLGSAYRSLGDFRKAIEYHEKHLEIAIEVGD 85 6778888999999999***************************99865 PP == domain 3 score: 2.5 bits; conditional E-value: 0.37 Rapsyn_N 42 kfrllGylitahsemGkykealefslaqlniaeeled 78 +r lG+ + +G ++ a e+ ++ l+ia e+ d FUN_002331-T1 132 AYRSLGIA---YQSLGDFRKASEYHKKHLEIAIEVGD 165 56666665...5579*****************99877 PP == domain 4 score: 11.3 bits; conditional E-value: 0.00062 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeel 76 dr+++ r G + +ah +G ++ a+e+ + l+ia e+ FUN_002331-T1 164 GDRDGQGRAYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEV 203 588999999***************************9886 PP == domain 5 score: 2.0 bits; conditional E-value: 0.5 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G + a+e+ + l+ia e+ FUN_002331-T1 253 YGGLGNAYRSLGDLRKAIEYHEKHLEIAIEV 283 678889999*****************99886 PP == domain 6 score: 9.5 bits; conditional E-value: 0.0024 Rapsyn_N 21 dtekalrvWrkvlkkts...dredkfrllGylitahsemGkykealefslaqlniaeeled 78 d ka+ + k l t dr+ + G l +a+ +G + a+e+ + l+ia e+ d FUN_002331-T1 305 DFRKAIEYYEKCLEITKevgDRDREGSVYGNLGNAYWSLGDLRKAIEYHEKHLEIAIEVGD 365 678899999998877761114555567****************************999865 PP == domain 7 score: 5.7 bits; conditional E-value: 0.037 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002331-T1 374 GGLGNAYQSLGDFRKAIEYHEKHLEIAIEVG 404 7788999********************9976 PP == domain 8 score: 4.0 bits; conditional E-value: 0.12 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l++a e+ FUN_002331-T1 413 YGNLGNAYQSLGYFRKAIEYLEKSLETAIEVG 444 688999********************999875 PP == domain 9 score: 12.4 bits; conditional E-value: 0.00029 Rapsyn_N 21 dtekalrvWrkvlkktsdredkf...rllGylitahsemGkykealefslaqlniaeeled 78 d ka+ k l t + +d+f r G l +a+ +G ++ a+++ ++l+ia e+ d FUN_002331-T1 465 DLRKAIDYHEKCLEITKEVGDRFvegRAYGNLGNAYKSLGDFRKAIKYHEKRLEIAIEISD 525 667899999999*********9988889****************************99876 PP == domain 10 score: 7.6 bits; conditional E-value: 0.0091 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeeled 78 dr + + G l +a+ +G ++ a+e+ + l+i+ e+ d FUN_002331-T1 525 DRIGEGKAYGSLGNAYRSLGDFRKAIEYHEKCLEISIEVGD 565 66667778899*************************99877 PP == domain 11 score: 6.6 bits; conditional E-value: 0.019 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeeled 78 dr++ r G l +a+ +G ++ a+e+ + l+i++e+ d FUN_002331-T1 565 DRDEEGRAYGGLGNAYQSLGDHRKAIEYHEKCLEITKEVGD 605 67788899999***************************987 PP == domain 12 score: 13.4 bits; conditional E-value: 0.00015 Rapsyn_N 21 dtekalrvWrkvlkktsdredkf...rllGylitahsemGkykealefslaqlniaeeledP 79 d ka++ k l t + +d+ G+l +a+ +G ++ a+e+ ++l+ia e++d FUN_002331-T1 625 DHRKAIYSLEKCLEITKEVGDRVgegSAYGILGNAYDSLGDHRKAIEYHEKRLEIAIEVDDR 686 78899999999997776555544222899*******************************96 PP == domain 13 score: 2.6 bits; conditional E-value: 0.33 Rapsyn_N 43 frllGylitahsemGkykealefslaqlniaeel 76 + lGy+++ +G ++ a+e+ + l+i+ e+ FUN_002331-T1 693 YGNLGYVYQ---SLGDFRKAIEYHEKCLEITIEV 723 556888887...5899*******99999998776 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.8 0.0 0.0096 5.9 42 137 .. 57 152 .. 21 155 .. 0.64 2 ! 7.8 0.1 0.0045 2.7 42 144 .. 57 159 .. 49 195 .. 0.81 3 ! 9.8 0.1 0.0012 0.7 42 140 .. 137 235 .. 128 239 .. 0.90 4 ! 21.6 0.0 2.9e-07 0.00018 50 181 .. 185 316 .. 172 325 .. 0.92 5 ! 19.5 0.0 1.2e-06 0.00075 41 180 .. 216 355 .. 210 360 .. 0.87 6 ! 17.2 0.0 6.2e-06 0.0038 42 180 .. 377 515 .. 372 524 .. 0.93 7 ! 15.5 0.0 2.1e-05 0.013 41 143 .. 536 638 .. 530 646 .. 0.93 8 ! 14.8 0.0 3.3e-05 0.02 43 147 .. 658 762 .. 652 774 .. 0.91 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0096 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 + ay+ ++++A e ++k e+ +++++ +nay + ++y + d ++A+e ek ei +e g+ ++ + +++ y++ +d++kA e FUN_002331-T1 57 GSAYRSLGDFRKAIEYHEKHLEIAIEVGDRVGEGNAYGNLGNAYDSLdDFQKAIEYHEKHLEIVIEVGNRVGEGSAYRSLGIAYQSL-GDFRKASE 151 456666666667777777777777777777777777777777776654566777777777777777666666666666666666654.66666655 PP SNAP 137 a 137 + FUN_002331-T1 152 Y 152 4 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0045 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 + ay+ ++++A e ++k e+ +++++ +nay + ++y + d ++A+e ek ei +e g+ ++ + +++ y++ +d++kA e FUN_002331-T1 57 GSAYRSLGDFRKAIEYHEKHLEIAIEVGDRVGEGNAYGNLGNAYDSLdDFQKAIEYHEKHLEIVIEVGNRVGEGSAYRSLGIAYQSL-GDFRKASE 151 6789999999**********************************9975899*****************9999999999999999977.9***9999 PP SNAP 137 aYeqAadl 144 + ++ ++ FUN_002331-T1 152 YHKKHLEI 159 98887665 PP == domain 3 score: 9.8 bits; conditional E-value: 0.0012 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 + ay+ ++++A+e + k e+ +++++d ++ay + ++ ++ d +A+e ek ei +e g+ ++ + ++++ y++ d++kAie FUN_002331-T1 137 GIAYQSLGDFRKASEYHKKHLEIAIEVGDRDGQGRAYGNIGNAHYSVgDFRKAIEYHEKNLEIAIEVGNRVGEGNAYGNLGNAYNSL-VDFQKAIE 231 5678888899*****************************9998666559***********************************987.******** PP SNAP 137 aYeq 140 + e+ FUN_002331-T1 232 CHEK 235 9987 PP == domain 4 score: 21.6 bits; conditional E-value: 2.9e-07 SNAP 50 kwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadl 144 ++++A e ++k e+ +++++ +nay + ++y++ d ++A+e+ ek ei +e g+ + ++ + +++ y++ +dl+kAie+ e+ ++ FUN_002331-T1 185 DFRKAIEYHEKNLEIAIEVGNRVGEGNAYGNLGNAYNSLvDFQKAIECHEKHLEISIEVGNRVKEGSAYGGLGNAYRSL-GDLRKAIEYHEKHLEI 279 5788999999999999999****************9986699*******************99999**********987.**************** PP SNAP 145 yeqeeaealankcllkvAdlsaelekyekAieiyekv 181 + + a + ++ + ++ +l+++ kAie yek FUN_002331-T1 280 AIEVGHRAGQGMAYGNFGTVYQSLGDFRKAIEYYEKC 316 **99******************************985 PP == domain 5 score: 19.5 bits; conditional E-value: 1.2e-06 SNAP 41 AAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAi 135 +nay ++++A e+++k e++ +++++ + ++ay ++y++ d +A+e ek ei +e g + + + + +y++ +d++kAi FUN_002331-T1 216 LGNAYNSLVDFQKAIECHEKHLEISIEVGNRVKEGSAYGGLGNAYRSLgDLRKAIEYHEKHLEIAIEVGHRAGQGMAYGNFGTVYQSL-GDFRKAI 310 5788888889999999999999999999999999999999999999977999999999999999999999999999999999999977.9999999 PP SNAP 136 eaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e+Ye+ ++ ++ + + +++ ++ + + +l+++ kAie ek FUN_002331-T1 311 EYYEKCLEITKEVGDRDREGSVYGNLGNAYWSLGDLRKAIEYHEK 355 999999999988888888888888888888888888888888775 PP == domain 6 score: 17.2 bits; conditional E-value: 6.2e-06 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay+ ++++A e ++k e+ +++++ ++ay + ++y++ +A+e lek+ e+ +e g+ + ++ ++++ y++ +dl+kAi+ FUN_002331-T1 377 GNAYQSLGDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGNLGNAYQSLgYFRKAIEYLEKSLETAIEVGNRDGEGRTCANLGNAYDSL-GDLRKAID 471 689999999************************************986999**********************************87.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ ++ ++ + ++ ++ + + +l+++ kAi+ ek FUN_002331-T1 472 YHEKCLEITKEVGDRFVEGRAYGNLGNAYKSLGDFRKAIKYHEK 515 *******9999999999999999999999999999999998886 PP == domain 7 score: 15.5 bits; conditional E-value: 2.1e-05 SNAP 41 AAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAi 135 +nay+ ++++A e ++k+ e++ +++++de ++ay ++y++ d +A+e ek+ ei e g + ++ + +++ y++ +d +kAi FUN_002331-T1 536 LGNAYRSLGDFRKAIEYHEKCLEISIEVGDRDEEGRAYGGLGNAYQSLgDHRKAIEYHEKCLEITKEVGDRDGEGRTYGNLGSAYDSL-GDHRKAI 630 589******************************************9986999**********************************87.******* PP SNAP 136 eaYeqAad 143 + e+ + FUN_002331-T1 631 YSLEKCLE 638 99998766 PP == domain 8 score: 14.8 bits; conditional E-value: 3.3e-05 SNAP 43 nayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAiea 137 nay ++++A e ++k e+ +++++d +nay + +y++ d +A+e ek+ ei +e g+ + + +i++ y + +++e+A+++ FUN_002331-T1 658 NAYDSLGDHRKAIEYHEKRLEIAIEVDDRDGEGNAYGNLGYVYQSLgDFRKAIEYHEKCLEITIEVGNRAAEGMSHHNIGQGYFSL-GQFENALDK 752 556666678899999****************************997799*******************999999**********87.********* PP SNAP 138 YeqAadlyeq 147 ++ A +++++ FUN_002331-T1 753 FDSAVKVFNT 762 ******9986 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.4 2.5e+02 6 22 .. 56 72 .. 55 74 .. 0.93 2 ? 1.9 0.1 1 6.2e+02 5 22 .. 95 112 .. 90 115 .. 0.72 3 ? 0.2 0.1 3.7 2.2e+03 6 19 .. 136 149 .. 132 152 .. 0.87 4 ? 2.8 0.0 0.52 3.1e+02 6 22 .. 256 272 .. 255 274 .. 0.93 5 ! 8.3 0.0 0.0098 5.9 7 28 .. 297 318 .. 295 319 .. 0.90 6 ? 1.6 0.0 1.3 7.7e+02 6 22 .. 336 352 .. 335 354 .. 0.92 7 ? 3.1 0.0 0.44 2.7e+02 6 22 .. 376 392 .. 375 394 .. 0.93 8 ? 1.7 0.1 1.2 7.1e+02 5 25 .. 415 435 .. 410 439 .. 0.71 9 ? 2.9 0.0 0.5 3e+02 6 23 .. 456 473 .. 455 478 .. 0.84 10 ? 3.5 0.0 0.32 2e+02 5 22 .. 495 512 .. 492 514 .. 0.92 11 ? 4.3 0.0 0.18 1.1e+02 6 25 .. 536 555 .. 535 559 .. 0.85 12 ? 4.5 0.0 0.15 94 6 23 .. 576 593 .. 575 598 .. 0.85 13 ? 7.5 0.0 0.016 10 6 28 .. 616 638 .. 615 639 .. 0.93 14 ? 2.6 0.0 0.64 3.9e+02 6 22 .. 656 672 .. 655 674 .. 0.93 15 ? 4.1 0.0 0.21 1.3e+02 6 23 .. 696 713 .. 695 718 .. 0.85 16 ? 3.5 0.0 0.31 1.9e+02 6 28 .. 736 758 .. 734 763 .. 0.84 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.4 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002331-T1 56 LGSAYRSLGDFRKAIEY 72 799***********986 PP == domain 2 score: 1.9 bits; conditional E-value: 1 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y l+d+++A+++ FUN_002331-T1 95 NLGNAYDSLDDFQKAIEY 112 467777777777777765 PP == domain 3 score: 0.2 bits; conditional E-value: 3.7 TPR_6 6 lalsylelgdkdeA 19 l+ +y+ lgd+ +A FUN_002331-T1 136 LGIAYQSLGDFRKA 149 899********999 PP == domain 4 score: 2.8 bits; conditional E-value: 0.52 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd +A+++ FUN_002331-T1 256 LGNAYRSLGDLRKAIEY 272 899***********986 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0098 TPR_6 7 alsylelgdkdeAkaalqrlik 28 + y+ lgd+ +A+++++++++ FUN_002331-T1 297 GTVYQSLGDFRKAIEYYEKCLE 318 678999*************986 PP == domain 6 score: 1.6 bits; conditional E-value: 1.3 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd +A+++ FUN_002331-T1 336 LGNAYWSLGDLRKAIEY 352 89************986 PP == domain 7 score: 3.1 bits; conditional E-value: 0.44 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002331-T1 376 LGNAYQSLGDFRKAIEY 392 899***********986 PP == domain 8 score: 1.7 bits; conditional E-value: 1.2 TPR_6 5 klalsylelgdkdeAkaalqr 25 +l+ +y+ lg + +A+++l++ FUN_002331-T1 415 NLGNAYQSLGYFRKAIEYLEK 435 467777777777777777776 PP == domain 9 score: 2.9 bits; conditional E-value: 0.5 TPR_6 6 lalsylelgdkdeAkaal 23 l+ +y lgd +A+++ FUN_002331-T1 456 LGNAYDSLGDLRKAIDYH 473 89*************985 PP == domain 10 score: 3.5 bits; conditional E-value: 0.32 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002331-T1 495 NLGNAYKSLGDFRKAIKY 512 589************986 PP == domain 11 score: 4.3 bits; conditional E-value: 0.18 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd+ +A+++ ++ FUN_002331-T1 536 LGNAYRSLGDFRKAIEYHEK 555 799************98655 PP == domain 12 score: 4.5 bits; conditional E-value: 0.15 TPR_6 6 lalsylelgdkdeAkaal 23 l+ +y+ lgd+ +A+++ FUN_002331-T1 576 LGNAYQSLGDHRKAIEYH 593 899************985 PP == domain 13 score: 7.5 bits; conditional E-value: 0.016 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 l+ +y lgd+ +A+ l+++++ FUN_002331-T1 616 LGSAYDSLGDHRKAIYSLEKCLE 638 89******************986 PP == domain 14 score: 2.6 bits; conditional E-value: 0.64 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002331-T1 656 LGNAYDSLGDHRKAIEY 672 899***********986 PP == domain 15 score: 4.1 bits; conditional E-value: 0.21 TPR_6 6 lalsylelgdkdeAkaal 23 l++ y+ lgd+ +A+++ FUN_002331-T1 696 LGYVYQSLGDFRKAIEYH 713 9**************985 PP == domain 16 score: 3.5 bits; conditional E-value: 0.31 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 +++ y+ lg++++A++ +++ +k FUN_002331-T1 736 IGQGYFSLGQFENALDKFDSAVK 758 78889999999999999998887 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.24 1.5e+02 33 112 .. 3 82 .. 1 89 [. 0.71 2 ! 9.5 0.0 0.0013 0.76 14 155 .. 63 203 .. 57 208 .. 0.86 3 ! 18.3 0.0 2.7e-06 0.0016 42 186 .. 212 355 .. 207 361 .. 0.67 4 ! 15.6 0.0 1.7e-05 0.01 9 150 .. 298 438 .. 297 447 .. 0.86 5 ! 8.6 0.0 0.0023 1.4 41 155 .. 371 483 .. 365 488 .. 0.85 6 ! 15.0 0.0 2.6e-05 0.016 43 190 .. 453 599 .. 446 604 .. 0.92 7 ! 7.6 0.0 0.0046 2.8 40 150 .. 650 758 .. 619 775 .. 0.81 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.24 TPR_MalT 33 eddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqe 112 ++++ +++l+ + G + +gd+ +A + + + ar+ ++ a+ +++ +r G++++A+e ++ l+ a e FUN_002331-T1 3 SEQIGFKVLVFGSAGSDMSTLGDFRKAIEYHERHLKVAREVGDRVGEGNAYGSLGSAYRSLGDFRKAIEYHEKHLEIAIE 82 56667777777777777888888777777766666667766666667777888888888888888888887777777655 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0013 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ e d + a+ +lG a+ + d+++A + ++ ++ + ++ a+++++ ++ G++++A e ++ l+ FUN_002331-T1 63 LGDFRKAIEYHEKHLEIAIEvGDRVGEGNAYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEVGNRVGEGSAYRSLGIAYQSLGDFRKASEYHKKHLE 158 5777777777777777654323444557888******************9999999999999999999**************************** PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 a e + + g ++ ++ +y +d+ +A ++ +++++++ ++ FUN_002331-T1 159 IAIEVGDRD--GQGRAYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEV 203 *****9995..999**************************9997665 PP == domain 3 score: 18.3 bits; conditional E-value: 2.7e-06 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 a+ +lG a+ + d+++A + ++ +++ + ++ a+ ++++ +r G+L++A+e ++ l+ a e + +a g+++ + ++ +d FUN_002331-T1 212 AYGNLGNAYNSLVDFQKAIECHEKHLEISIEVGNRVKEGSAYGGLGNAYRSLGDLRKAIEYHEKHLEIAIEVGHRA--GQGMAYGNFGTVYQSLGD 305 5667777777777777777777777777766666666677777777777777777777777777777777776663..677777777777777777 PP TPR_MalT 138 LeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqr 186 + +A ++ ++ +++++++ ++++ y l + + G+l+ A ++ ++ FUN_002331-T1 306 FRKAIEYYEKCLEITKEVgDRDREGSVYGNLGNAYWSLGDLRKAIEYHEK 355 77777777777777777656677766666666666666666666665554 PP == domain 4 score: 15.6 bits; conditional E-value: 1.7e-05 TPR_MalT 9 llavsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaety 103 +++ s g++ +a+e+ ++ L++++e r ++++ +lG a+ +gdl +A + ++ ++a + ++ +a+ ++++ ++ G++++A+e FUN_002331-T1 298 TVYQSLGDFRKAIEYYEKCLEITKEVGDRDReGSVYGNLGNAYWSLGDLRKAIEYHEKHLEIAIEVGDRVGEGIAYGGLGNAYQSLGDFRKAIEYH 393 5677899****************997666777**********************9999999999999999999*********************** PP TPR_MalT 104 qqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiq 150 ++ l+ a e + + g ++ l++ + + + +A ++l+++++ FUN_002331-T1 394 EKHLEIAIEVGDRV--GEGSAYGNLGNAYQSLGYFRKAIEYLEKSLE 438 ******99988885..6667777888888888888888887777766 PP == domain 5 score: 8.6 bits; conditional E-value: 0.0023 TPR_MalT 41 latlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwn 136 +a+ lG a++ +gd+ +A + ++ ++a + ++ a+ +++ ++ G++++A+e ++ l+ a e + + g ++ l++ + + FUN_002331-T1 371 IAYGGLGNAYQSLGDFRKAIEYHEKHLEIAIEVGDRVGEGSAYGNLGNAYQSLGYFRKAIEYLEKSLETAIEVGNRD--GEGRTCANLGNAYDSLG 464 56677999999999999999999998888888888888899999999999999999999999999999999999885..88888889999999999 PP TPR_MalT 137 dLeeAeqhlqqgiqlgrql 155 dL +A + ++ +++++++ FUN_002331-T1 465 DLRKAIDYHEKCLEITKEV 483 9999999999998888876 PP == domain 6 score: 15.0 bits; conditional E-value: 2.6e-05 TPR_MalT 43 tlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwndL 138 ++lG a+ +gdl +A + ++ +++++ ++ v a+ +++ + G++++A++ ++ l+ a e + + g ++ +l++ ++ +d+ FUN_002331-T1 453 CANLGNAYDSLGDLRKAIDYHEKCLEITKEVGDRFVEGRAYGNLGNAYKSLGDFRKAIKYHEKRLEIAIEISDRI--GEGKAYGSLGNAYRSLGDF 546 5699*****************************9999**********************************9996..88999************** PP TPR_MalT 139 eeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerl 190 +A ++ ++ ++++ ++ +++ +ay l + ++ G+++ A ++ ++ ++ FUN_002331-T1 547 RKAIEYHEKCLEISIEVgDRDEEGRAYGGLGNAYQSLGDHRKAIEYHEKCLEI 599 ***************99788*********************999998877665 PP == domain 7 score: 7.6 bits; conditional E-value: 0.0046 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 ++a+ lG a+ +gd +A + ++ ++a + d+ + a+ ++++++ G++++A+e ++ l+ e + +a++ + + ++ + FUN_002331-T1 650 GSAYGILGNAYDSLGDHRKAIEYHEKRLEIAIEVDDRDGEGNAYGNLGYVYQSLGDFRKAIEYHEKCLEITIEVGNRAAEGMSHH--NIGQGYFSL 743 5677889999999999999999998888999888888888999999999999999999999999999999999988876655544..556667777 PP TPR_MalT 136 ndLeeAeqhlqqgiq 150 +++e+A + +++ FUN_002331-T1 744 GQFENALDKFDSAVK 758 777777766666655 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.25 1.5e+02 14 34 .] 51 71 .. 49 71 .. 0.92 2 ? 6.5 0.1 0.027 16 14 34 .] 91 111 .. 89 111 .. 0.93 3 ? 0.7 0.0 2 1.2e+03 15 32 .. 132 149 .. 130 149 .. 0.89 4 ? -1.2 0.0 8.1 4.9e+03 15 34 .] 172 191 .. 170 199 .. 0.67 5 ? 1.1 0.2 1.5 9.1e+02 14 33 .. 211 230 .. 209 231 .. 0.80 6 ? -0.1 0.0 3.6 2.2e+03 2 12 .. 226 236 .. 225 239 .. 0.83 7 ? 4.6 0.0 0.11 68 14 34 .] 251 271 .. 248 271 .. 0.90 8 ? 3.7 0.0 0.21 1.3e+02 15 34 .] 292 311 .. 289 311 .. 0.92 9 ? 1.1 0.0 1.5 9.1e+02 15 34 .] 332 351 .. 327 351 .. 0.89 10 ? 3.4 0.0 0.26 1.6e+02 15 34 .] 372 391 .. 370 391 .. 0.91 11 ? 1.9 0.1 0.84 5.1e+02 15 27 .. 412 424 .. 409 431 .. 0.78 12 ? 2.7 0.0 0.45 2.7e+02 18 33 .. 455 470 .. 454 471 .. 0.93 13 ? 7.3 0.0 0.015 9.2 15 33 .. 492 510 .. 490 511 .. 0.92 14 ? 5.4 0.0 0.06 36 14 34 .] 531 551 .. 528 551 .. 0.92 15 ? 4.3 0.0 0.14 87 15 34 .] 572 591 .. 568 591 .. 0.91 16 ? 3.6 0.0 0.24 1.5e+02 15 33 .. 612 630 .. 609 631 .. 0.91 17 ? 3.2 0.0 0.3 1.9e+02 15 34 .] 652 671 .. 649 671 .. 0.91 18 ! 9.2 0.0 0.0038 2.3 13 34 .] 690 711 .. 679 711 .. 0.86 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.25 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+ +++ +G++ +A++ FUN_002331-T1 51 NAYGSLGSAYRSLGDFRKAIE 71 79****************985 PP == domain 2 score: 6.5 bits; conditional E-value: 0.027 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL++++ ++++++A++ FUN_002331-T1 91 NAYGNLGNAYDSLDDFQKAIE 111 79*****************85 PP == domain 3 score: 0.7 bits; conditional E-value: 2 TPR_17 15 ayynLArlllnnGqleeA 32 ay L+++++ +G++ +A FUN_002331-T1 132 AYRSLGIAYQSLGDFRKA 149 8999*********99887 PP == domain 4 score: -1.2 bits; conditional E-value: 8.1 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay n ++++ G++ +A++ FUN_002331-T1 172 AYGNIGNAHYSVGDFRKAIE 191 66677777766666666653 PP == domain 5 score: 1.1 bits; conditional E-value: 1.5 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay nL++++ + ++++A+ FUN_002331-T1 211 NAYGNLGNAYNSLVDFQKAI 230 79********9877776665 PP == domain 6 score: -0.1 bits; conditional E-value: 3.6 TPR_17 2 ylkaleldPnn 12 ++ka+e++ ++ FUN_002331-T1 226 FQKAIECHEKH 236 89*****9776 PP == domain 7 score: 4.6 bits; conditional E-value: 0.11 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay L+++++ +G+l +A++ FUN_002331-T1 251 SAYGGLGNAYRSLGDLRKAIE 271 58999*************985 PP == domain 8 score: 3.7 bits; conditional E-value: 0.21 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay n +++++ +G++ +A++ FUN_002331-T1 292 AYGNFGTVYQSLGDFRKAIE 311 8****************985 PP == domain 9 score: 1.1 bits; conditional E-value: 1.5 TPR_17 15 ayynLArlllnnGqleeAlq 34 +y nL++++ +G+l +A++ FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIE 351 799******99999999985 PP == domain 10 score: 3.4 bits; conditional E-value: 0.26 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIE 391 7999*************985 PP == domain 11 score: 1.9 bits; conditional E-value: 0.84 TPR_17 15 ayynLArlllnnG 27 ay nL+++++ +G FUN_002331-T1 412 AYGNLGNAYQSLG 424 899******9988 PP == domain 12 score: 2.7 bits; conditional E-value: 0.45 TPR_17 18 nLArlllnnGqleeAl 33 nL++++ +G+l +A+ FUN_002331-T1 455 NLGNAYDSLGDLRKAI 470 9************997 PP == domain 13 score: 7.3 bits; conditional E-value: 0.015 TPR_17 15 ayynLArlllnnGqleeAl 33 ay nL+++++ +G++ +A+ FUN_002331-T1 492 AYGNLGNAYKSLGDFRKAI 510 8***************998 PP == domain 14 score: 5.4 bits; conditional E-value: 0.06 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002331-T1 531 KAYGSLGNAYRSLGDFRKAIE 551 69****************985 PP == domain 15 score: 4.3 bits; conditional E-value: 0.14 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002331-T1 572 AYGGLGNAYQSLGDHRKAIE 591 8999*************985 PP == domain 16 score: 3.6 bits; conditional E-value: 0.24 TPR_17 15 ayynLArlllnnGqleeAl 33 y nL+ ++ +G++ +A+ FUN_002331-T1 612 TYGNLGSAYDSLGDHRKAI 630 699*************997 PP == domain 17 score: 3.2 bits; conditional E-value: 0.3 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L++++ +G++ +A++ FUN_002331-T1 652 AYGILGNAYDSLGDHRKAIE 671 8999*************985 PP == domain 18 score: 9.2 bits; conditional E-value: 0.0038 TPR_17 13 adayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002331-T1 690 GNAYGNLGYVYQSLGDFRKAIE 711 689****************985 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.1 0.24 1.5e+02 37 70 .. 51 84 .. 26 151 .. 0.79 2 ? 1.7 0.1 0.41 2.5e+02 38 132 .. 92 189 .. 89 190 .. 0.69 3 ? 3.6 0.0 0.11 68 37 70 .. 171 204 .. 166 208 .. 0.86 4 ? 4.3 0.0 0.066 40 38 71 .. 212 245 .. 210 251 .. 0.87 5 ? 3.1 0.0 0.16 94 39 72 .. 253 286 .. 250 289 .. 0.88 6 ! 8.2 0.0 0.0042 2.5 37 68 .. 291 322 .. 287 326 .. 0.90 7 ? 3.0 0.0 0.17 1e+02 39 68 .. 333 362 .. 330 368 .. 0.85 8 ? 0.8 0.0 0.77 4.7e+02 41 68 .. 375 402 .. 371 408 .. 0.83 9 ? 1.4 0.0 0.51 3.1e+02 38 70 .. 412 444 .. 410 447 .. 0.89 10 ? 4.8 0.1 0.045 28 15 69 .. 429 483 .. 426 487 .. 0.80 11 ? 3.2 0.0 0.15 90 37 65 .. 491 519 .. 489 528 .. 0.86 12 ? 3.3 0.0 0.14 84 38 67 .. 532 561 .. 529 566 .. 0.87 13 ? 4.3 0.0 0.069 42 37 68 .. 571 602 .. 564 606 .. 0.86 14 ? 2.2 0.0 0.3 1.8e+02 38 70 .. 612 644 .. 609 648 .. 0.87 15 ? -1.5 0.0 4 2.4e+03 42 64 .. 656 678 .. 651 686 .. 0.83 16 ? 6.3 0.0 0.016 10 38 73 .. 692 727 .. 689 758 .. 0.82 17 ? 1.1 0.0 0.63 3.8e+02 37 64 .. 731 758 .. 727 769 .. 0.85 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.24 RPN7 37 raledlaehyakigdlenAlkayerarekttslg 70 +a+ l+ y + gd+++A+++ e+ +e ++ g FUN_002331-T1 51 NAYGSLGSAYRSLGDFRKAIEYHEKHLEIAIEVG 84 5777888999999999999999998887666555 PP == domain 2 score: 1.7 bits; conditional E-value: 0.41 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffn...dwalvskylekaksliekggdwerrnrlkvyeGlaalairkfk 130 a+ +l++ y + d+++A+++ e+ +e ++ g+ + + +gi+++ d+ ++s+y +k ++ + gd++ + r G a+ ++++f FUN_002331-T1 92 AYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEVGNRVGEGSAYRSLGIAYQslgDFRKASEYHKKHLEIAIEVGDRDGQGRAYGNIGNAHYSVGDFR 187 677888888888888888888888888888888888777777777777632336677777777766666666777766666666666666666666 PP RPN7 131 eA 132 +A FUN_002331-T1 188 KA 189 55 PP == domain 3 score: 3.6 bits; conditional E-value: 0.11 RPN7 37 raledlaehyakigdlenAlkayerarekttslg 70 ra+ ++++ ++++gd+++A+++ e+ +e ++ g FUN_002331-T1 171 RAYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEVG 204 678899******************9888776665 PP == domain 4 score: 4.3 bits; conditional E-value: 0.066 RPN7 38 aledlaehyakigdlenAlkayerarekttslgh 71 a+ +l++ y + d+++A+++ e+ +e + g+ FUN_002331-T1 212 AYGNLGNAYNSLVDFQKAIECHEKHLEISIEVGN 245 7889********************9998777666 PP == domain 5 score: 3.1 bits; conditional E-value: 0.16 RPN7 39 ledlaehyakigdlenAlkayerarekttslghk 72 + l++ y + gdl++A+++ e+ +e ++ gh FUN_002331-T1 253 YGGLGNAYRSLGDLRKAIEYHEKHLEIAIEVGHR 286 5668999*****************9999998886 PP == domain 6 score: 8.2 bits; conditional E-value: 0.0042 RPN7 37 raledlaehyakigdlenAlkayerarektts 68 +a+ +++ y + gd+++A+++ye+++e t FUN_002331-T1 291 MAYGNFGTVYQSLGDFRKAIEYYEKCLEITKE 322 789999********************998766 PP == domain 7 score: 3.0 bits; conditional E-value: 0.17 RPN7 39 ledlaehyakigdlenAlkayerarektts 68 + +l++ y + gdl++A+++ e+ +e ++ FUN_002331-T1 333 YGNLGNAYWSLGDLRKAIEYHEKHLEIAIE 362 66899*****************99886665 PP == domain 8 score: 0.8 bits; conditional E-value: 0.77 RPN7 41 dlaehyakigdlenAlkayerarektts 68 l++ y + gd+++A+++ e+ +e ++ FUN_002331-T1 375 GLGNAYQSLGDFRKAIEYHEKHLEIAIE 402 58999***************99886665 PP == domain 9 score: 1.4 bits; conditional E-value: 0.51 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ +l++ y + g +++A++++e+ +e ++ g FUN_002331-T1 412 AYGNLGNAYQSLGYFRKAIEYLEKSLETAIEVG 444 68899*******************999887765 PP == domain 10 score: 4.8 bits; conditional E-value: 0.045 RPN7 15 eleeLeaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttsl 69 +e Le+ l+ a e r+ +l++ y + gdl++A+++ e+++e t FUN_002331-T1 429 AIEYLEKSLETAIEVGNRDGEGRTCANLGNAYDSLGDLRKAIDYHEKCLEITKEV 483 567777777777766666666677889*********************9988765 PP == domain 11 score: 3.2 bits; conditional E-value: 0.15 RPN7 37 raledlaehyakigdlenAlkayerarek 65 ra+ +l++ y + gd+++A+k+ e+ +e FUN_002331-T1 491 RAYGNLGNAYKSLGDFRKAIKYHEKRLEI 519 57899*****************9997775 PP == domain 12 score: 3.3 bits; conditional E-value: 0.14 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ l++ y + gd+++A+++ e+++e + FUN_002331-T1 532 AYGSLGNAYRSLGDFRKAIEYHEKCLEISI 561 678899******************998665 PP == domain 13 score: 4.3 bits; conditional E-value: 0.069 RPN7 37 raledlaehyakigdlenAlkayerarektts 68 ra+ l++ y + gd+++A+++ e+++e t FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKAIEYHEKCLEITKE 602 5688899*******************998765 PP == domain 14 score: 2.2 bits; conditional E-value: 0.3 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 ++ +l+ y + gd+++A+ ++e+++e t g FUN_002331-T1 612 TYGNLGSAYDSLGDHRKAIYSLEKCLEITKEVG 644 6789999******************99887765 PP == domain 15 score: -1.5 bits; conditional E-value: 4 RPN7 42 laehyakigdlenAlkayerare 64 l++ y + gd+++A+++ e+ +e FUN_002331-T1 656 LGNAYDSLGDHRKAIEYHEKRLE 678 7889999*********9998766 PP == domain 16 score: 6.3 bits; conditional E-value: 0.016 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l+ y + gd+++A+++ e+++e t+ g+ + FUN_002331-T1 692 AYGNLGYVYQSLGDFRKAIEYHEKCLEITIEVGNRA 727 78899999*******************999888765 PP == domain 17 score: 1.1 bits; conditional E-value: 0.63 RPN7 37 raledlaehyakigdlenAlkayerare 64 + ++++++ y++ g++enAl+ + a++ FUN_002331-T1 731 MSHHNIGQGYFSLGQFENALDKFDSAVK 758 6789999*************99988765 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.0 0.056 34 100 210 .. 51 157 .. 26 162 .. 0.66 2 ? 1.3 0.0 0.44 2.7e+02 101 171 .. 132 200 .. 126 209 .. 0.80 3 ? 6.0 0.0 0.016 9.8 97 173 .. 248 322 .. 225 330 .. 0.80 4 ? 0.6 0.0 0.73 4.4e+02 101 170 .. 332 399 .. 325 405 .. 0.59 5 ? 6.6 0.0 0.01 6.1 102 173 .. 413 482 .. 389 520 .. 0.60 6 ? 5.9 0.0 0.017 10 101 173 .. 532 602 .. 521 608 .. 0.90 7 ? 2.8 0.0 0.15 89 101 170 .. 612 679 .. 606 683 .. 0.86 8 ! 9.6 0.0 0.0013 0.79 100 203 .. 651 757 .. 628 768 .. 0.81 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.056 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqk 195 + y +lG + lg +a++ ++ Lei + D ++++ +L + y+ + f++a +++++ lei+ + G+ + + +l + yq FUN_002331-T1 51 NAYGSLGSAYRSLGDFRKAIEYHEKHLEIAIEV--GDRVGEGNAYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEV-GN-RVGEGSAYRSLGIAYQS 142 557777777777777777777777777776555..4666667888889999999999999999999998887543.32.23334455666666666 PP TPR_NPHP3 196 qdkhdlaeplkkrav 210 + a +k+ + FUN_002331-T1 143 LGDFRKASEYHKKHL 157 666666666666655 PP == domain 2 score: 1.3 bits; conditional E-value: 0.44 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 y +lG + lg +a + ++ Lei + d D +r++ ++ + + g f++a +++++ lei FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEYHKKHLEIAIEVGDRDG--QGRAYGNIGNAHYSVGDFRKAIEYHEKNLEIA 200 6888888888888888998888899998877766665..57888888888888999999999888888875 PP == domain 3 score: 6.0 bits; conditional E-value: 0.016 TPR_NPHP3 97 kvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDh.PlvarslhqLagLyaqwgkfstaealykqaleiyen 173 k + y lG+ + lg l +a++ ++ Lei + h + ++ + ++y+ g f++a ++y++ lei+++ FUN_002331-T1 248 KEGSAYGGLGNAYRSLGDLRKAIEYHEKHLEIAIEV---GHrAGQGMAYGNFGTVYQSLGDFRKAIEYYEKCLEITKE 322 446789999999******************996555...44134566788999**********************986 PP == domain 4 score: 0.6 bits; conditional E-value: 0.73 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 +y lG+ lg l +a++ ++ Lei + d + ++ L + y+ g f++a +++++ lei FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEYHEKHLEIAIEVGD--RVGEGIAYGGLGNAYQSLGDFRKAIEYHEKHLEI 399 5666666666666666666666666666555533..2223333445666666666666666666666655 PP == domain 5 score: 6.6 bits; conditional E-value: 0.01 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 y lG+ + lg +a++ L+++Le + + D +r+ +L + y+ g +++a +++++ lei+++ FUN_002331-T1 413 YGNLGNAYQSLGYFRKAIEYLEKSLETAIEVGNRDG--EGRTCANLGNAYDSLGDLRKAIDYHEKCLEITKE 482 555555555555555555555555554444433333..3667777777777777777777777777777654 PP == domain 6 score: 5.9 bits; conditional E-value: 0.017 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 y +lG+ + lg +a++ ++ Lei + d D+ +r++ L + y+ g +++a +++++ lei+++ FUN_002331-T1 532 AYGSLGNAYRSLGDFRKAIEYHEKCLEISIEVGDRDEE--GRAYGGLGNAYQSLGDHRKAIEYHEKCLEITKE 602 6999************************9999888875..899999***********************9976 PP == domain 7 score: 2.8 bits; conditional E-value: 0.15 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 +y lG lg +a+ +L++ Lei + D ++++ L + y+ g +++a +++++ lei FUN_002331-T1 612 TYGNLGSAYDSLGDHRKAIYSLEKCLEITKEV--GDRVGEGSAYGILGNAYDSLGDHRKAIEYHEKRLEI 679 6899999999******************8887..667777888888999999999999999999888887 PP == domain 8 score: 9.6 bits; conditional E-value: 0.0013 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy.....enayGsdhelvakeleala 190 + y +lG+ lg +a++ ++ Lei + d D ++++ +L +y+ g f++a +++++ lei+ + a G+ h+ + + + +l FUN_002331-T1 651 SAYGILGNAYDSLGDHRKAIEYHEKRLEIAIEVDDRDG--EGNAYGNLGYVYQSLGDFRKAIEYHEKCLEITievgnRAAEGMSHHNIGQGYFSLG 744 57899999999999999999999999999877755555..588899999******************99997333334578999999999999999 PP TPR_NPHP3 191 llyqkqdkhdlae 203 ++ + dk+d a FUN_002331-T1 745 QFENALDKFDSAV 757 9999999999875 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.2 0.035 22 10 58 .. 23 77 .. 19 82 .. 0.85 2 ! 7.9 0.1 0.0098 6 3 57 .. 56 116 .. 55 122 .. 0.85 3 ? 3.1 0.0 0.32 2e+02 4 53 .. 137 192 .. 134 195 .. 0.63 4 ? 5.0 0.0 0.08 48 3 52 .. 176 231 .. 175 240 .. 0.85 5 ? 5.1 0.1 0.076 46 31 58 .. 250 277 .. 234 282 .. 0.82 6 ! 11.6 0.0 0.00069 0.42 4 59 .. 297 358 .. 295 363 .. 0.89 7 ? 7.7 0.2 0.011 6.7 3 58 .. 336 397 .. 335 403 .. 0.82 8 ? 4.8 0.2 0.094 57 3 58 .. 376 437 .. 369 442 .. 0.72 9 ? 2.3 0.1 0.56 3.4e+02 3 27 .. 416 440 .. 414 475 .. 0.66 10 ? 1.3 0.0 1.2 7.1e+02 3 19 .. 496 512 .. 488 520 .. 0.73 11 ! 8.7 0.1 0.0058 3.5 3 53 .. 536 592 .. 535 599 .. 0.84 12 ? 1.6 0.1 0.9 5.5e+02 31 53 .. 650 672 .. 615 682 .. 0.74 13 ? 2.7 0.1 0.41 2.5e+02 4 53 .. 657 712 .. 656 718 .. 0.71 14 ? 2.8 0.0 0.38 2.3e+02 3 27 .. 736 760 .. 734 772 .. 0.83 15 ? 0.2 0.2 2.5 1.5e+03 5 38 .. 790 824 .. 787 825 .. 0.86 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.035 TPR_16 10 agdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 +gd++ A+++ e+ l+ A+ lG a+ +g++ +A+++ ++ l FUN_002331-T1 23 LGDFRKAIEYHERHLKVArevgdrVGEGNAYGSLGSAYRSLGDFRKAIEYHEKHL 77 6899999999999999999999996689999****************99876666 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0098 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraa 57 l+ a++ +gd++ A+++ le a++ + A+ +lG a+ + ++++A+++ ++ FUN_002331-T1 56 LGSAYRSLGDFRKAIEYhekhLEIAIEVGdrVGEGNAYGNLGNAYDSLDDFQKAIEYHEKH 116 6899999*******875444499999999*977999*******************986665 PP == domain 3 score: 3.1 bits; conditional E-value: 0.32 TPR_16 4 araalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 + a+ +gd++ A ++ le a++ + +A+ + G a++ g++ +A+++ FUN_002331-T1 137 GIAYQSLGDFRKASEYhkkhLEIAIEVGdrDGQGRAYGNIGNAHYSVGDFRKAIEY 192 66677777777775432222667777777755677777777777777777777654 PP == domain 4 score: 5.0 bits; conditional E-value: 0.08 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaa 52 ++a++ gd++ A+++ le a++ + A+ +lG a+ + ++++A++ FUN_002331-T1 176 IGNAHYSVGDFRKAIEYheknLEIAIEVGnrVGEGNAYGNLGNAYNSLVDFQKAIE 231 5899999*******975444488899999997789999999999999999999985 PP == domain 5 score: 5.1 bits; conditional E-value: 0.076 TPR_16 31 aaAllglGlallrqgrlaeAaaayraal 58 A+ glG a+ +g+l +A+++ ++ l FUN_002331-T1 250 GSAYGGLGNAYRSLGDLRKAIEYHEKHL 277 579999***********99999876666 PP == domain 6 score: 11.6 bits; conditional E-value: 0.00069 TPR_16 4 araalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalr 59 ++ + +gd++ A++++e l+ + + +lG a++ +g+l +A+++ ++ l+ FUN_002331-T1 297 GTVYQSLGDFRKAIEYYEKCLEITkevgdrDREGSVYGNLGNAYWSLGDLRKAIEYHEKHLE 358 788999************999988889999999*********************99777665 PP == domain 7 score: 7.7 bits; conditional E-value: 0.011 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd + A+++ le a++ + A+ glG a+ +g++ +A+++ ++ l FUN_002331-T1 336 LGNAYWSLGDLRKAIEYhekhLEIAIEVGdrVGEGIAYGGLGNAYQSLGDFRKAIEYHEKHL 397 79999999999999875444488899999997789999999999999999999998866666 PP == domain 8 score: 4.8 bits; conditional E-value: 0.094 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ le a++ + A+ +lG a+ +g + +A++++++ l FUN_002331-T1 376 LGNAYQSLGDFRKAIEYhekhLEIAIEVGdrVGEGSAYGNLGNAYQSLGYFRKAIEYLEKSL 437 78899999999999865333377777777775567777777777777777777777776655 PP == domain 9 score: 2.3 bits; conditional E-value: 0.56 TPR_16 3 laraalaagdyddAaaaleaalrrn 27 l++a+ +g ++ A+++le l+ FUN_002331-T1 416 LGNAYQSLGYFRKAIEYLEKSLETA 440 7899999999999999999887765 PP == domain 10 score: 1.3 bits; conditional E-value: 1.2 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002331-T1 496 LGNAYKSLGDFRKAIKY 512 57777777777777654 PP == domain 11 score: 8.7 bits; conditional E-value: 0.0058 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a++ +gd++ A+++ e l+ e +A+ glG a+ +g++ +A+++ FUN_002331-T1 536 LGNAYRSLGDFRKAIEYHEKCLEISievgdrDEEGRAYGGLGNAYQSLGDHRKAIEY 592 799***********987555555445555**99*******************99986 PP == domain 12 score: 1.6 bits; conditional E-value: 0.9 TPR_16 31 aaAllglGlallrqgrlaeAaaa 53 A+ lG a+ +g++ +A+++ FUN_002331-T1 650 GSAYGILGNAYDSLGDHRKAIEY 672 56788888888888888888854 PP == domain 13 score: 2.7 bits; conditional E-value: 0.41 TPR_16 4 araalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 ++a+ +gd + A+++ le a++ + A+ +lG+++ +g++ +A+++ FUN_002331-T1 657 GNAYDSLGDHRKAIEYhekrLEIAIEVDdrDGEGNAYGNLGYVYQSLGDFRKAIEY 712 66777777777776532222888888888866788888888888888888888865 PP == domain 14 score: 2.8 bits; conditional E-value: 0.38 TPR_16 3 laraalaagdyddAaaaleaalrrn 27 ++ ++ +g+++ A+ ++ a++ + FUN_002331-T1 736 IGQGYFSLGQFENALDKFDSAVKVF 760 5778889999999999999999876 PP == domain 15 score: 0.2 bits; conditional E-value: 2.5 TPR_16 5 raalaagdyddAaaaleaalrrn.PeaaaAllglG 38 r++l+ g+ d+A+ a+++ +++ ++ ++++l+ FUN_002331-T1 790 RSLLKIGKIDEALFAADQGRAQTlSDNLLMQYELA 824 789999*******9999999998888888888887 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.2 7.2e+02 222 245 .. 17 40 .. 11 43 .. 0.81 2 ? 3.8 0.0 0.074 45 219 243 .. 54 78 .. 49 82 .. 0.89 3 ? -1.6 0.0 3.3 2e+03 219 242 .. 94 117 .. 91 119 .. 0.87 4 ? -2.6 0.1 6.9 4.2e+03 220 243 .. 135 158 .. 131 160 .. 0.86 5 ? 1.5 0.0 0.38 2.3e+02 218 243 .. 253 278 .. 242 282 .. 0.87 6 ? 1.5 0.0 0.38 2.3e+02 219 244 .. 294 319 .. 289 325 .. 0.86 7 ? 4.0 0.0 0.064 39 212 243 .. 327 358 .. 320 362 .. 0.86 8 ? 1.1 0.0 0.5 3.1e+02 220 243 .. 375 398 .. 372 402 .. 0.88 9 ? -0.4 0.0 1.4 8.5e+02 223 241 .. 411 429 .. 410 441 .. 0.55 10 ? -2.2 0.0 5.2 3.2e+03 221 243 .. 456 478 .. 453 486 .. 0.85 11 ? 0.6 0.0 0.73 4.4e+02 219 243 .. 494 518 .. 484 521 .. 0.87 12 ? -0.5 0.0 1.5 9.1e+02 219 241 .. 534 556 .. 530 562 .. 0.86 13 ? 1.9 0.0 0.28 1.7e+02 218 243 .. 573 598 .. 563 603 .. 0.83 14 ? -2.5 0.0 6.4 3.9e+03 219 240 .. 614 635 .. 611 643 .. 0.80 15 ? 1.9 0.0 0.28 1.7e+02 218 243 .. 653 678 .. 644 684 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.2 TPR_15 222 AaAllllgqnrkALpyfrkkaaqn 245 ++ +++lg+ rkA +y +++++ + FUN_002331-T1 17 GSDMSTLGDFRKAIEYHERHLKVA 40 45599**************98865 PP == domain 2 score: 3.8 bits; conditional E-value: 0.074 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + +++A+ lg+ rkA +y +k+++ FUN_002331-T1 54 GSLGSAYRSLGDFRKAIEYHEKHLE 78 679******************9976 PP == domain 3 score: -1.6 bits; conditional E-value: 3.3 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ l++ +kA +y +k++ FUN_002331-T1 94 GNLGNAYDSLDDFQKAIEYHEKHL 117 56899***************9986 PP == domain 4 score: -2.6 bits; conditional E-value: 6.9 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y +k+++ FUN_002331-T1 135 SLGIAYQSLGDFRKASEYHKKHLE 158 67889*************999875 PP == domain 5 score: 1.5 bits; conditional E-value: 0.38 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ ++ A+ lg+ rkA +y +k+++ FUN_002331-T1 253 YGGLGNAYRSLGDLRKAIEYHEKHLE 278 567899****************9976 PP == domain 6 score: 1.5 bits; conditional E-value: 0.38 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + +++ + lg+ rkA +y++k ++ FUN_002331-T1 294 GNFGTVYQSLGDFRKAIEYYEKCLEI 319 679999***************97655 PP == domain 7 score: 4.0 bits; conditional E-value: 0.064 TPR_15 212 aadasLweayAaAllllgqnrkALpyfrkkaa 243 +++ s ++ ++ A+ lg+ rkA +y +k+++ FUN_002331-T1 327 DREGSVYGNLGNAYWSLGDLRKAIEYHEKHLE 358 567788999*******************9976 PP == domain 8 score: 1.1 bits; conditional E-value: 0.5 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y +k+++ FUN_002331-T1 375 GLGNAYQSLGDFRKAIEYHEKHLE 398 5899****************9976 PP == domain 9 score: -0.4 bits; conditional E-value: 1.4 TPR_15 223 aAllllgqnrkALpyfrkk 241 +A+ lg+ + L yfrk FUN_002331-T1 411 SAYGNLGNAYQSLGYFRKA 429 5555666666666666553 PP == domain 10 score: -2.2 bits; conditional E-value: 5.2 TPR_15 221 yAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA y +k ++ FUN_002331-T1 456 LGNAYDSLGDLRKAIDYHEKCLE 478 7899*************999665 PP == domain 11 score: 0.6 bits; conditional E-value: 0.73 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002331-T1 494 GNLGNAYKSLGDFRKAIKYHEKRLE 518 67899**************999865 PP == domain 12 score: -0.5 bits; conditional E-value: 1.5 TPR_15 219 eayAaAllllgqnrkALpyfrkk 241 + ++ A+ lg+ rkA +y +k FUN_002331-T1 534 GSLGNAYRSLGDFRKAIEYHEKC 556 67899**************9985 PP == domain 13 score: 1.9 bits; conditional E-value: 0.28 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ ++ A+ lg+ rkA +y +k ++ FUN_002331-T1 573 YGGLGNAYQSLGDHRKAIEYHEKCLE 598 567899**************999665 PP == domain 14 score: -2.5 bits; conditional E-value: 6.4 TPR_15 219 eayAaAllllgqnrkALpyfrk 240 + +++A+ lg+ rkA ++k FUN_002331-T1 614 GNLGSAYDSLGDHRKAIYSLEK 635 6799************876666 PP == domain 15 score: 1.9 bits; conditional E-value: 0.28 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ ++ A+ lg+ rkA +y +k+++ FUN_002331-T1 653 YGILGNAYDSLGDHRKAIEYHEKRLE 678 567999***************99875 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 2.3 1.4e+03 35 57 .. 56 78 .. 49 87 .. 0.83 2 ? -1.6 0.0 6.5 3.9e+03 35 51 .. 96 112 .. 89 122 .. 0.62 3 ? 4.6 0.0 0.078 47 31 51 .. 132 152 .. 128 167 .. 0.85 4 ? -1.4 0.0 5.9 3.6e+03 34 51 .. 175 192 .. 162 200 .. 0.71 5 ! 9.0 0.0 0.0032 1.9 35 66 .. 296 327 .. 291 329 .. 0.85 6 ? 0.5 0.0 1.5 9e+02 36 57 .. 377 398 .. 371 406 .. 0.82 7 ? 4.0 0.0 0.12 75 32 57 .. 413 438 .. 409 446 .. 0.87 8 ? -1.5 0.0 6.3 3.8e+03 36 59 .. 457 480 .. 453 488 .. 0.81 9 ? -0.9 0.0 3.9 2.4e+03 32 51 .. 493 512 .. 480 526 .. 0.66 10 ? 0.5 0.0 1.5 8.9e+02 36 59 .. 537 560 .. 531 569 .. 0.82 11 ? 0.3 0.0 1.7 1e+03 36 62 .. 577 603 .. 570 608 .. 0.82 12 ? 2.9 0.0 0.27 1.6e+02 32 60 .. 613 641 .. 609 647 .. 0.86 13 ? 4.2 0.0 0.1 62 33 58 .. 694 719 .. 690 727 .. 0.88 14 ? -0.4 0.0 2.9 1.8e+03 36 56 .. 737 757 .. 735 759 .. 0.82 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2.3 TPR_9 35 rGllyaqlgcleaAladLeayla 57 G++y lg++ +A+++ e+ l+ FUN_002331-T1 56 LGSAYRSLGDFRKAIEYHEKHLE 78 699999********998776665 PP == domain 2 score: -1.6 bits; conditional E-value: 6.5 TPR_9 35 rGllyaqlgcleaAlad 51 G +y l+++++A+++ FUN_002331-T1 96 LGNAYDSLDDFQKAIEY 112 45555556666666554 PP == domain 3 score: 4.6 bits; conditional E-value: 0.078 TPR_9 31 errdrGllyaqlgcleaAlad 51 +r G++y+ lg++ +A ++ FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEY 152 6899**************886 PP == domain 4 score: -1.4 bits; conditional E-value: 5.9 TPR_9 34 drGllyaqlgcleaAlad 51 + G +++ +g++ +A+++ FUN_002331-T1 175 NIGNAHYSVGDFRKAIEY 192 456677777888777775 PP == domain 5 score: 9.0 bits; conditional E-value: 0.0032 TPR_9 35 rGllyaqlgcleaAladLeaylalapdapdae 66 G +y+ lg++ +A+++ e++l++ + d++ FUN_002331-T1 296 FGTVYQSLGDFRKAIEYYEKCLEITKEVGDRD 327 5899******************9988766665 PP == domain 6 score: 0.5 bits; conditional E-value: 1.5 TPR_9 36 GllyaqlgcleaAladLeayla 57 G +y+ lg++ +A+++ e+ l+ FUN_002331-T1 377 GNAYQSLGDFRKAIEYHEKHLE 398 77999********998766665 PP == domain 7 score: 4.0 bits; conditional E-value: 0.12 TPR_9 32 rrdrGllyaqlgcleaAladLeayla 57 + + G +y+ lg + +A+++Le+ l+ FUN_002331-T1 413 YGNLGNAYQSLGYFRKAIEYLEKSLE 438 567899****************8776 PP == domain 8 score: -1.5 bits; conditional E-value: 6.3 TPR_9 36 GllyaqlgcleaAladLeaylala 59 G +y lg+l +A+++ e++l++ FUN_002331-T1 457 GNAYDSLGDLRKAIDYHEKCLEIT 480 7788899******99999999876 PP == domain 9 score: -0.9 bits; conditional E-value: 3.9 TPR_9 32 rrdrGllyaqlgcleaAlad 51 + + G +y lg++ +A+++ FUN_002331-T1 493 YGNLGNAYKSLGDFRKAIKY 512 44555666666666666654 PP == domain 10 score: 0.5 bits; conditional E-value: 1.5 TPR_9 36 GllyaqlgcleaAladLeaylala 59 G +y lg++ +A+++ e++l+++ FUN_002331-T1 537 GNAYRSLGDFRKAIEYHEKCLEIS 560 778999*********999999876 PP == domain 11 score: 0.3 bits; conditional E-value: 1.7 TPR_9 36 GllyaqlgcleaAladLeaylalapda 62 G +y+ lg+ +A+++ e++l++ + FUN_002331-T1 577 GNAYQSLGDHRKAIEYHEKCLEITKEV 603 77999**********999999887655 PP == domain 12 score: 2.9 bits; conditional E-value: 0.27 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalap 60 + + G++y lg+ +A+ Le++l++ FUN_002331-T1 613 YGNLGSAYDSLGDHRKAIYSLEKCLEITK 641 56789********************9875 PP == domain 13 score: 4.2 bits; conditional E-value: 0.1 TPR_9 33 rdrGllyaqlgcleaAladLeaylal 58 + G +y+ lg++ +A+++ e++l++ FUN_002331-T1 694 GNLGYVYQSLGDFRKAIEYHEKCLEI 719 57899*************99999875 PP == domain 14 score: -0.4 bits; conditional E-value: 2.9 TPR_9 36 GllyaqlgcleaAladLeayl 56 G+ y+ lg++e Al+ ++ ++ FUN_002331-T1 737 GQGYFSLGQFENALDKFDSAV 757 556899********9998765 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 3.1 1.9e+03 16 31 .. 22 37 .. 20 38 .. 0.88 2 ? 1.1 0.0 1 6.2e+02 14 31 .. 60 77 .. 58 80 .. 0.88 3 ? 2.7 0.0 0.32 1.9e+02 16 31 .. 182 197 .. 178 201 .. 0.90 4 ? 1.2 0.0 0.94 5.7e+02 14 31 .. 260 277 .. 258 280 .. 0.88 5 ? 1.3 0.0 0.89 5.4e+02 14 31 .. 340 357 .. 337 360 .. 0.88 6 ? 1.3 0.0 0.87 5.3e+02 14 31 .. 380 397 .. 378 400 .. 0.89 7 ? 3.0 0.0 0.26 1.6e+02 14 31 .. 460 477 .. 456 480 .. 0.87 8 ? 0.3 0.0 1.8 1.1e+03 14 31 .. 500 517 .. 498 520 .. 0.88 9 ? 0.1 0.0 2 1.2e+03 14 31 .. 540 557 .. 539 560 .. 0.86 10 ? -1.9 0.0 8.7 5.3e+03 14 31 .. 660 677 .. 659 679 .. 0.85 11 ? 0.6 0.0 1.4 8.5e+02 14 31 .. 700 717 .. 696 720 .. 0.82 12 ? 2.7 0.0 0.32 1.9e+02 13 28 .. 739 754 .. 732 762 .. 0.83 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.1 DUF2977 16 lvGgledgidvdednl 31 + G ++++i+++e l FUN_002331-T1 22 TLGDFRKAIEYHERHL 37 68**********9866 PP == domain 2 score: 1.1 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002331-T1 60 YRSLGDFRKAIEYHEKHL 77 7789***********987 PP == domain 3 score: 2.7 bits; conditional E-value: 0.32 DUF2977 16 lvGgledgidvdednl 31 vG ++++i+++e+nl FUN_002331-T1 182 SVGDFRKAIEYHEKNL 197 58************98 PP == domain 4 score: 1.2 bits; conditional E-value: 0.94 DUF2977 14 YvlvGgledgidvdednl 31 Y G l+++i+++e+ l FUN_002331-T1 260 YRSLGDLRKAIEYHEKHL 277 7789***********987 PP == domain 5 score: 1.3 bits; conditional E-value: 0.89 DUF2977 14 YvlvGgledgidvdednl 31 Y G l+++i+++e+ l FUN_002331-T1 340 YWSLGDLRKAIEYHEKHL 357 7789***********987 PP == domain 6 score: 1.3 bits; conditional E-value: 0.87 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002331-T1 380 YQSLGDFRKAIEYHEKHL 397 7889***********987 PP == domain 7 score: 3.0 bits; conditional E-value: 0.26 DUF2977 14 YvlvGgledgidvdednl 31 Y G l+++id++e+ l FUN_002331-T1 460 YDSLGDLRKAIDYHEKCL 477 6779**********9865 PP == domain 8 score: 0.3 bits; conditional E-value: 1.8 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i ++e+ l FUN_002331-T1 500 YKSLGDFRKAIKYHEKRL 517 7789***********987 PP == domain 9 score: 0.1 bits; conditional E-value: 2 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002331-T1 540 YRSLGDFRKAIEYHEKCL 557 7789**********9865 PP == domain 10 score: -1.9 bits; conditional E-value: 8.7 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++i+++e+ l FUN_002331-T1 660 YDSLGDHRKAIEYHEKRL 677 6678999*******9876 PP == domain 11 score: 0.6 bits; conditional E-value: 1.4 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002331-T1 700 YQSLGDFRKAIEYHEKCL 717 5578**********9865 PP == domain 12 score: 2.7 bits; conditional E-value: 0.32 DUF2977 13 sYvlvGgledgidvde 28 +Y G++e+++d + FUN_002331-T1 739 GYFSLGQFENALDKFD 754 8999*********444 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 6.2 3.8e+03 5 46 .. 24 71 .. 23 76 .. 0.59 2 ? 1.4 0.1 0.96 5.8e+02 5 46 .. 64 111 .. 60 118 .. 0.73 3 ? -1.7 0.0 8.9 5.4e+03 23 46 .. 168 191 .. 140 195 .. 0.63 4 ? -0.2 0.0 3 1.8e+03 27 46 .. 252 271 .. 249 279 .. 0.85 5 ! 9.9 0.0 0.0021 1.3 5 46 .. 304 351 .. 301 359 .. 0.87 6 ? 1.0 0.0 1.2 7.5e+02 27 46 .. 372 391 .. 369 400 .. 0.85 7 ? 1.4 0.0 0.92 5.6e+02 5 52 .. 384 437 .. 382 440 .. 0.66 8 ? 2.3 0.1 0.49 3e+02 7 45 .. 426 470 .. 420 478 .. 0.83 9 ? 5.1 0.0 0.067 41 5 46 .. 464 511 .. 462 515 .. 0.93 10 ! 8.5 0.0 0.0059 3.6 4 46 .. 543 591 .. 540 597 .. 0.90 11 ? 0.9 0.0 1.4 8.2e+02 5 46 .. 624 671 .. 622 672 .. 0.80 12 ? 2.2 0.0 0.52 3.2e+02 5 46 .. 664 711 .. 662 719 .. 0.70 13 ? -1.4 0.1 6.9 4.2e+03 35 55 .. 792 812 .. 790 817 .. 0.81 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 6.2 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+ + + a+ L+ a+ lg++ +A++ FUN_002331-T1 24 GDFRKAIEYHERHLKVAREvgdrvgEGNAYGSLGSAYRSLGDFRKAIE 71 566666666666444433333344456666667777777777777765 PP == domain 2 score: 1.4 bits; conditional E-value: 0.96 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ l+++ +A++ FUN_002331-T1 64 GDFRKAIEYHEKHLEIAIEvgdrvgEGNAYGNLGNAYDSLDDFQKAIE 111 788888888888665532222334488899999999999999999986 PP == domain 3 score: -1.7 bits; conditional E-value: 8.9 TPR_19 23 dnaearllLArallalgrldeAea 46 + +a+ + ++a++ g++ +A++ FUN_002331-T1 168 GQGRAYGNIGNAHYSVGDFRKAIE 191 466777777777777777777765 PP == domain 4 score: -0.2 bits; conditional E-value: 3 TPR_19 27 arllLArallalgrldeAea 46 a+ +L++a+ lg+l +A++ FUN_002331-T1 252 AYGGLGNAYRSLGDLRKAIE 271 67899999999999999987 PP == domain 5 score: 9.9 bits; conditional E-value: 0.0021 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A++++e+ l++ + ++ +L++a+ lg+l +A++ FUN_002331-T1 304 GDFRKAIEYYEKCLEITKEvgdrdrEGSVYGNLGNAYWSLGDLRKAIE 351 9***************555555557999999***************87 PP == domain 6 score: 1.0 bits; conditional E-value: 1.2 TPR_19 27 arllLArallalgrldeAea 46 a+ +L++a+ lg++ +A++ FUN_002331-T1 372 AYGGLGNAYQSLGDFRKAIE 391 67799999999999999987 PP == domain 7 score: 1.4 bits; conditional E-value: 0.92 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalp 52 gd+ +A+++ e+ l+++ + a+ +L++a+ lg + +A++ L++ + FUN_002331-T1 384 GDFRKAIEYHEKHLEIAIEvgdrvgEGSAYGNLGNAYQSLGYFRKAIEYLEKSL 437 566666666666554422222233367788899999999999999999998755 PP == domain 8 score: 2.3 bits; conditional E-value: 0.49 TPR_19 7 ydeAlalLeqalae......dPdnaearllLArallalgrldeAe 45 + +A+++Le+ l+ + + +++L++a+ lg+l +A+ FUN_002331-T1 426 FRKAIEYLEKSLETaievgnRDGEGRTCANLGNAYDSLGDLRKAI 470 678999999988887777756669999999***********9997 PP == domain 9 score: 5.1 bits; conditional E-value: 0.067 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+ + e+ l++ + +a+ +L++a+ lg++ +A++ FUN_002331-T1 464 GDLRKAIDYHEKCLEITKEvgdrfvEGRAYGNLGNAYKSLGDFRKAIK 511 89999*******99999999999999********************87 PP == domain 10 score: 8.5 bits; conditional E-value: 0.0059 TPR_19 4 egdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + +a+ +L++a+ lg+ +A++ FUN_002331-T1 543 LGDFRKAIEYHEKCLEIsievgdRDEEGRAYGGLGNAYQSLGDHRKAIE 591 69*************99888885666*********************87 PP == domain 11 score: 0.9 bits; conditional E-value: 1.4 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+ Le+ l++ + a+ L++a+ lg+ +A++ FUN_002331-T1 624 GDHRKAIYSLEKCLEITKEvgdrvgEGSAYGILGNAYDSLGDHRKAIE 671 899999999999999977766666677788888888888888888875 PP == domain 12 score: 2.2 bits; conditional E-value: 0.52 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + a+ +L+ ++ lg++ +A++ FUN_002331-T1 664 GDHRKAIEYHEKRLEIaievddRDGEGNAYGNLGYVYQSLGDFRKAIE 711 777777777777443333333245588888899999999999999976 PP == domain 13 score: -1.4 bits; conditional E-value: 6.9 TPR_19 35 llalgrldeAealLaalpaad 55 ll+ g++deA ++++a+ FUN_002331-T1 792 LLKIGKIDEALFAADQGRAQT 812 8999999**999988888775 PP >> DUF7542 Family of unknown function (DUF7542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 3.7 2.2e+03 19 35 .. 20 36 .. 15 41 .. 0.85 2 ? 2.1 0.0 0.37 2.3e+02 17 35 .. 58 76 .. 52 83 .. 0.86 3 ? -0.8 0.0 2.9 1.8e+03 17 35 .. 98 116 .. 92 121 .. 0.85 4 ? -1.0 0.0 3.5 2.1e+03 18 35 .. 179 196 .. 175 202 .. 0.83 5 ? 2.2 0.0 0.33 2e+02 17 35 .. 258 276 .. 246 287 .. 0.86 6 ? 0.8 0.0 0.94 5.7e+02 17 36 .. 338 357 .. 334 375 .. 0.84 7 ? 2.6 0.0 0.26 1.6e+02 17 35 .. 378 396 .. 371 403 .. 0.87 8 ? 4.4 0.0 0.068 41 14 34 .. 455 475 .. 449 482 .. 0.83 9 ? 1.1 0.0 0.72 4.4e+02 17 35 .. 498 516 .. 488 525 .. 0.86 10 ? 0.9 0.0 0.83 5.1e+02 17 34 .. 538 555 .. 533 562 .. 0.88 11 ? 2.1 0.0 0.36 2.2e+02 17 34 .. 578 595 .. 572 602 .. 0.86 12 ? -2.2 0.0 8 4.9e+03 18 35 .. 612 629 .. 610 634 .. 0.70 13 ? 3.6 0.0 0.13 77 17 35 .. 658 676 .. 654 684 .. 0.87 14 ? 0.6 0.0 1.1 6.7e+02 18 34 .. 699 715 .. 695 730 .. 0.87 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 3.7 DUF7542 19 fdslraARealddHese 35 ++l++ R+a++ He++ FUN_002331-T1 20 MSTLGDFRKAIEYHERH 36 578999*********86 PP == domain 2 score: 2.1 bits; conditional E-value: 0.37 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002331-T1 58 SAYRSLGDFRKAIEYHEKH 76 789**************86 PP == domain 3 score: -0.8 bits; conditional E-value: 2.9 DUF7542 17 etfdslraARealddHese 35 +++dsl + +a++ He++ FUN_002331-T1 98 NAYDSLDDFQKAIEYHEKH 116 6899999999999999975 PP == domain 4 score: -1.0 bits; conditional E-value: 3.5 DUF7542 18 tfdslraARealddHese 35 ++ s+++ R+a++ He++ FUN_002331-T1 179 AHYSVGDFRKAIEYHEKN 196 6779999*********87 PP == domain 5 score: 2.2 bits; conditional E-value: 0.33 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002331-T1 258 NAYRSLGDLRKAIEYHEKH 276 789**************86 PP == domain 6 score: 0.8 bits; conditional E-value: 0.94 DUF7542 17 etfdslraARealddHeset 36 +++ sl++ R+a++ He++ FUN_002331-T1 338 NAYWSLGDLRKAIEYHEKHL 357 67889************865 PP == domain 7 score: 2.6 bits; conditional E-value: 0.26 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002331-T1 378 NAYQSLGDFRKAIEYHEKH 396 689**************86 PP == domain 8 score: 4.4 bits; conditional E-value: 0.068 DUF7542 14 efeetfdslraARealddHes 34 ++ +++dsl++ R+a+d He+ FUN_002331-T1 455 NLGNAYDSLGDLRKAIDYHEK 475 35689**************96 PP == domain 9 score: 1.1 bits; conditional E-value: 0.72 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He+ FUN_002331-T1 498 NAYKSLGDFRKAIKYHEKR 516 789*************986 PP == domain 10 score: 0.9 bits; conditional E-value: 0.83 DUF7542 17 etfdslraARealddHes 34 +++ sl++ R+a++ He+ FUN_002331-T1 538 NAYRSLGDFRKAIEYHEK 555 6899************96 PP == domain 11 score: 2.1 bits; conditional E-value: 0.36 DUF7542 17 etfdslraARealddHes 34 ++++sl++ R+a++ He+ FUN_002331-T1 578 NAYQSLGDHRKAIEYHEK 595 68999***********96 PP == domain 12 score: -2.2 bits; conditional E-value: 8 DUF7542 18 tfdslraARealddHese 35 t+ +l++A l dH+++ FUN_002331-T1 612 TYGNLGSAYDSLGDHRKA 629 567777777777777754 PP == domain 13 score: 3.6 bits; conditional E-value: 0.13 DUF7542 17 etfdslraARealddHese 35 +++dsl++ R+a++ He+ FUN_002331-T1 658 NAYDSLGDHRKAIEYHEKR 676 68**************986 PP == domain 14 score: 0.6 bits; conditional E-value: 1.1 DUF7542 18 tfdslraARealddHes 34 ++sl++ R+a++ He+ FUN_002331-T1 699 VYQSLGDFRKAIEYHEK 715 699************96 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.05 31 3 24 .. 53 74 .. 52 75 .. 0.91 2 ? -0.1 0.0 3.3 2e+03 2 24 .. 132 154 .. 131 155 .. 0.84 3 ? 0.2 0.0 2.7 1.7e+03 3 24 .. 173 194 .. 171 195 .. 0.80 4 ? 3.5 0.0 0.24 1.5e+02 3 24 .. 253 274 .. 251 275 .. 0.86 5 ? 1.5 0.0 1 6.1e+02 10 26 .. 300 316 .. 293 319 .. 0.85 6 ? 4.7 0.0 0.097 59 2 24 .. 332 354 .. 331 355 .. 0.89 7 ? 2.4 0.0 0.55 3.4e+02 3 24 .. 373 394 .. 371 395 .. 0.85 8 ? 3.4 0.1 0.26 1.6e+02 2 25 .. 412 435 .. 411 438 .. 0.88 9 ? 4.2 0.0 0.14 87 2 24 .. 492 514 .. 491 515 .. 0.88 10 ? 7.4 0.0 0.014 8.3 2 28 .. 532 558 .. 531 561 .. 0.89 11 ? 2.3 0.0 0.57 3.5e+02 3 26 .. 573 596 .. 571 599 .. 0.84 12 ? -1.2 0.0 7.7 4.7e+03 3 24 .. 653 674 .. 651 675 .. 0.77 13 ? 0.4 0.0 2.3 1.4e+03 9 26 .. 699 716 .. 692 719 .. 0.79 14 ? 1.2 0.0 1.3 8e+02 9 24 .. 739 754 .. 736 763 .. 0.86 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.05 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl s+y + G++++A+e+++ FUN_002331-T1 53 YGSLGSAYRSLGDFRKAIEYHE 74 99999**************987 PP == domain 2 score: -0.1 bits; conditional E-value: 3.3 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl +y + G++++A e++k FUN_002331-T1 132 AYRSLGIAYQSLGDFRKASEYHK 154 57777889999*******99987 PP == domain 3 score: 0.2 bits; conditional E-value: 2.7 PPR 3 ynslIsgycknGkleeAlelfk 24 y + +++ + G++++A+e+++ FUN_002331-T1 173 YGNIGNAHYSVGDFRKAIEYHE 194 55556889999********987 PP == domain 4 score: 3.5 bits; conditional E-value: 0.24 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G+l++A+e+++ FUN_002331-T1 253 YGGLGNAYRSLGDLRKAIEYHE 274 777779*************987 PP == domain 5 score: 1.5 bits; conditional E-value: 1 PPR 10 ycknGkleeAlelfkeM 26 y + G++++A+e++++ FUN_002331-T1 300 YQSLGDFRKAIEYYEKC 316 6678**********985 PP == domain 6 score: 4.7 bits; conditional E-value: 0.097 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G+l++A+e+++ FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEYHE 354 688899**************987 PP == domain 7 score: 2.4 bits; conditional E-value: 0.55 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002331-T1 373 YGGLGNAYQSLGDFRKAIEYHE 394 7777799************987 PP == domain 8 score: 3.4 bits; conditional E-value: 0.26 PPR 2 tynslIsgycknGkleeAlelfke 25 +y l ++y + G++++A+e++++ FUN_002331-T1 412 AYGNLGNAYQSLGYFRKAIEYLEK 435 6888899*************9987 PP == domain 9 score: 4.2 bits; conditional E-value: 0.14 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+++++ FUN_002331-T1 492 AYGNLGNAYKSLGDFRKAIKYHE 514 5888889************9987 PP == domain 10 score: 7.4 bits; conditional E-value: 0.014 PPR 2 tynslIsgycknGkleeAlelfkeMke 28 +y sl ++y + G++++A+e++++ +e FUN_002331-T1 532 AYGSLGNAYRSLGDFRKAIEYHEKCLE 558 59999****************998665 PP == domain 11 score: 2.3 bits; conditional E-value: 0.57 PPR 3 ynslIsgycknGkleeAlelfkeM 26 y l ++y + G++++A+e++++ FUN_002331-T1 573 YGGLGNAYQSLGDHRKAIEYHEKC 596 666779999**********99875 PP == domain 12 score: -1.2 bits; conditional E-value: 7.7 PPR 3 ynslIsgycknGkleeAlelfk 24 y +l ++y + G++++A+e+++ FUN_002331-T1 653 YGILGNAYDSLGDHRKAIEYHE 674 666777777899******9987 PP == domain 13 score: 0.4 bits; conditional E-value: 2.3 PPR 9 gycknGkleeAlelfkeM 26 +y + G++++A+e++++ FUN_002331-T1 699 VYQSLGDFRKAIEYHEKC 716 67789********99875 PP == domain 14 score: 1.2 bits; conditional E-value: 1.3 PPR 9 gycknGkleeAlelfk 24 gy + G++e Al+ f+ FUN_002331-T1 739 GYFSLGQFENALDKFD 754 8999999999999776 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.43 2.6e+02 30 68 .. 13 51 .. 10 56 .. 0.85 2 ? -0.6 0.0 3.3 2e+03 30 67 .. 53 90 .. 49 99 .. 0.77 3 ? -1.3 0.0 5.4 3.3e+03 30 62 .. 93 125 .. 88 134 .. 0.64 4 ? -1.2 0.0 4.9 3e+03 30 69 .. 213 252 .. 210 253 .. 0.86 5 ? 2.6 0.0 0.32 2e+02 30 69 .. 253 292 .. 249 312 .. 0.90 6 ? -0.2 0.0 2.5 1.5e+03 30 67 .. 293 330 .. 290 352 .. 0.74 7 ? 1.0 0.0 1 6.3e+02 29 69 .. 332 372 .. 330 374 .. 0.86 8 ? 0.1 0.0 2 1.2e+03 30 69 .. 373 412 .. 370 426 .. 0.79 9 ? 2.1 0.0 0.47 2.8e+02 30 69 .. 453 492 .. 450 512 .. 0.84 10 ? 0.2 0.0 1.8 1.1e+03 30 59 .. 493 522 .. 488 553 .. 0.67 11 ? 0.0 0.0 2.1 1.3e+03 31 67 .. 534 570 .. 530 611 .. 0.68 12 ? -0.5 0.0 3 1.8e+03 30 69 .. 613 652 .. 610 672 .. 0.73 13 ? -0.9 0.0 3.9 2.4e+03 30 56 .. 653 679 .. 650 693 .. 0.80 14 ? 1.0 0.0 1 6.2e+02 30 69 .. 693 732 .. 689 735 .. 0.87 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.43 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGm 68 ++ G +++tLgd +++++ ++ lk + ++ + G FUN_002331-T1 13 FGSAGSDMSTLGDFRKAIEYHERHLKVAREVGDRVGEGN 51 67789****************999999888888777765 PP == domain 2 score: -0.6 bits; conditional E-value: 3.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G + + Lgd +++++ ++ l+ + ++ + G FUN_002331-T1 53 YGSLGSAYRSLGDFRKAIEYHEKHLEIAIEVGDRVGEG 90 67788888999999999998888887777766665555 PP == domain 3 score: -1.3 bits; conditional E-value: 5.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLek 62 y+ +G++ L+d +++++ ++ l+ + ++ FUN_002331-T1 93 YGNLGNAYDSLDDFQKAIEYHEKHLEIVIEVGN 125 556677777777777777777776665555554 PP == domain 4 score: -1.2 bits; conditional E-value: 4.9 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G++ + L d +++++ ++ l+ + + ++ ++ G a FUN_002331-T1 213 YGNLGNAYNSLVDFQKAIECHEKHLEISIEVGNRVKEGSA 252 677899999999******9999999999999998888866 PP == domain 5 score: 2.6 bits; conditional E-value: 0.32 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G++ + Lgdl+++++ ++ l+ + ++ +Gma FUN_002331-T1 253 YGGLGNAYRSLGDLRKAIEYHEKHLEIAIEVGHRAGQGMA 292 667899999**************99999999999999998 PP == domain 6 score: -0.2 bits; conditional E-value: 2.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ G+ + Lgd +++++ +++ l+ +++ ++ + G FUN_002331-T1 293 YGNFGTVYQSLGDFRKAIEYYEKCLEITKEVGDRDREG 330 66677888888888888888888887777766554444 PP == domain 7 score: 1.0 bits; conditional E-value: 1 CODH_A_N 29 iyaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 +y+ +G++ Lgdl+++++ ++ l+ + ++ + G+a FUN_002331-T1 332 VYGNLGNAYWSLGDLRKAIEYHEKHLEIAIEVGDRVGEGIA 372 7889999999**********999999988888888877776 PP == domain 8 score: 0.1 bits; conditional E-value: 2 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G++ + Lgd +++++ ++ l+ + ++ + G a FUN_002331-T1 373 YGGLGNAYQSLGDFRKAIEYHEKHLEIAIEVGDRVGEGSA 412 6778999999999999999999988887777776666654 PP == domain 9 score: 2.1 bits; conditional E-value: 0.47 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 +a +G++ Lgdl+++++ ++ l+ +++ ++ + G a FUN_002331-T1 453 CANLGNAYDSLGDLRKAIDYHEKCLEITKEVGDRFVEGRA 492 5778999999999999999999999988888877777755 PP == domain 10 score: 0.2 bits; conditional E-value: 1.8 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G++ k Lgd +++++ ++ l+ + FUN_002331-T1 493 YGNLGNAYKSLGDFRKAIKYHEKRLEIAIE 522 455666667777777766666665554444 PP == domain 11 score: 0.0 bits; conditional E-value: 2.1 CODH_A_N 31 altGekvktLgdleevLnrarsllkeelkLekaldaG 67 + +G++ + Lgd +++++ ++ l+ + + ++ + G FUN_002331-T1 534 GSLGNAYRSLGDFRKAIEYHEKCLEISIEVGDRDEEG 570 5666777777777777777766666665555554444 PP == domain 12 score: -0.5 bits; conditional E-value: 3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G + Lgd ++++ ++++ l+ +++ ++ + G a FUN_002331-T1 613 YGNLGSAYDSLGDHRKAIYSLEKCLEITKEVGDRVGEGSA 652 5667777788888888888888877777776666666554 PP == domain 13 score: -0.9 bits; conditional E-value: 3.9 CODH_A_N 30 yaltGekvktLgdleevLnrarsllke 56 y+++G++ Lgd +++++ ++ l+ FUN_002331-T1 653 YGILGNAYDSLGDHRKAIEYHEKRLEI 679 8999***********999988887765 PP == domain 14 score: 1.0 bits; conditional E-value: 1 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G + Lgd +++++ ++ l+ + + ++ + Gm+ FUN_002331-T1 693 YGNLGYVYQSLGDFRKAIEYHEKCLEITIEVGNRAAEGMS 732 6677888899999999999999999999999999999997 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 6.7 4.1e+03 71 89 .. 25 43 .. 21 51 .. 0.86 2 ? -1.7 0.0 7.5 4.6e+03 71 88 .. 65 82 .. 59 90 .. 0.84 3 ? 1.4 0.0 0.86 5.2e+02 68 92 .. 102 126 .. 91 157 .. 0.78 4 ? -1.3 0.0 5.6 3.4e+03 71 89 .. 185 203 .. 181 216 .. 0.85 5 ? 3.9 0.0 0.14 84 71 92 .. 305 326 .. 299 336 .. 0.85 6 ? -1.5 0.0 6.7 4.1e+03 71 88 .. 385 402 .. 379 409 .. 0.82 7 ? 0.5 0.0 1.6 9.8e+02 74 92 .. 421 439 .. 413 451 .. 0.67 8 ? 0.7 0.0 1.3 8.1e+02 70 89 .. 464 483 .. 458 503 .. 0.86 9 ? -1.7 0.0 7.6 4.6e+03 70 88 .. 504 522 .. 489 532 .. 0.81 10 ? -1.9 0.0 8.9 5.4e+03 71 88 .. 545 562 .. 538 569 .. 0.78 11 ? -1.7 0.0 7.8 4.7e+03 71 91 .. 585 605 .. 580 611 .. 0.82 12 ? 0.0 0.0 2.2 1.4e+03 71 95 .. 705 729 .. 698 737 .. 0.81 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 6.7 DUF7018 71 llekaidhyekslklieea 89 ++ kai+++e+ lk+++e+ FUN_002331-T1 25 DFRKAIEYHERHLKVAREV 43 899***********99987 PP == domain 2 score: -1.7 bits; conditional E-value: 7.5 DUF7018 71 llekaidhyekslkliee 88 ++ kai+++ek l+++ e FUN_002331-T1 65 DFRKAIEYHEKHLEIAIE 82 899********9998766 PP == domain 3 score: 1.4 bits; conditional E-value: 0.86 DUF7018 68 vqkllekaidhyekslklieeavek 92 +++kai+++ek l+++ e+ ++ FUN_002331-T1 102 SLDDFQKAIEYHEKHLEIVIEVGNR 126 55799***********999887766 PP == domain 4 score: -1.3 bits; conditional E-value: 5.6 DUF7018 71 llekaidhyekslklieea 89 ++ kai+++ek l+++ e+ FUN_002331-T1 185 DFRKAIEYHEKNLEIAIEV 203 899*********9998776 PP == domain 5 score: 3.9 bits; conditional E-value: 0.14 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai++yek l++ +e+ ++ FUN_002331-T1 305 DFRKAIEYYEKCLEITKEVGDR 326 89*************9998655 PP == domain 6 score: -1.5 bits; conditional E-value: 6.7 DUF7018 71 llekaidhyekslkliee 88 ++ kai+++ek l+++ e FUN_002331-T1 385 DFRKAIEYHEKHLEIAIE 402 899********9998766 PP == domain 7 score: 0.5 bits; conditional E-value: 1.6 DUF7018 74 kaidhyekslklieeavek 92 +++++++k+++ +e+++e FUN_002331-T1 421 QSLGYFRKAIEYLEKSLET 439 5666666666666666553 PP == domain 8 score: 0.7 bits; conditional E-value: 1.3 DUF7018 70 kllekaidhyekslklieea 89 +l kaid++ek l++ +e+ FUN_002331-T1 464 GDLRKAIDYHEKCLEITKEV 483 5899**********999987 PP == domain 9 score: -1.7 bits; conditional E-value: 7.6 DUF7018 70 kllekaidhyekslkliee 88 ++ kai+++ek l+++ e FUN_002331-T1 504 GDFRKAIKYHEKRLEIAIE 522 4789999999999887655 PP == domain 10 score: -1.9 bits; conditional E-value: 8.9 DUF7018 71 llekaidhyekslkliee 88 ++ kai+++ek l++ e FUN_002331-T1 545 DFRKAIEYHEKCLEISIE 562 799999999999987655 PP == domain 11 score: -1.7 bits; conditional E-value: 7.8 DUF7018 71 llekaidhyekslklieeave 91 + kai+++ek l++ +e+ + FUN_002331-T1 585 DHRKAIEYHEKCLEITKEVGD 605 5679*********99998755 PP == domain 12 score: 0.0 bits; conditional E-value: 2.2 DUF7018 71 llekaidhyekslklieeavekkdk 95 ++ kai+++ek l++ e+ ++ ++ FUN_002331-T1 705 DFRKAIEYHEKCLEITIEVGNRAAE 729 899**********999888777665 PP >> Bleomycin_resist_prot_dom Bleomycin resistance protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 8 4.9e+03 8 36 .. 65 95 .. 57 109 .. 0.78 2 ? -1.8 0.0 9.8 6e+03 7 33 .. 104 130 .. 97 133 .. 0.84 3 ? 0.5 0.0 1.9 1.2e+03 3 38 .. 180 214 .. 177 237 .. 0.81 4 ? -1.5 0.0 7.8 4.7e+03 7 38 .. 224 254 .. 217 267 .. 0.80 5 ? 1.3 0.0 1.1 6.4e+02 8 41 .. 265 300 .. 257 302 .. 0.84 6 ? 5.9 0.1 0.039 24 1 37 [. 297 333 .. 297 342 .. 0.83 7 ? 1.2 0.0 1.1 6.7e+02 7 38 .. 344 375 .. 337 383 .. 0.79 8 ? -1.7 0.0 9.5 5.7e+03 8 37 .. 385 413 .. 377 424 .. 0.79 9 ? 0.1 0.0 2.6 1.6e+03 10 33 .. 427 450 .. 417 462 .. 0.88 10 ? -0.0 0.0 2.7 1.6e+03 8 38 .. 505 534 .. 497 543 .. 0.82 11 ? 4.6 0.0 0.1 62 8 37 .. 545 574 .. 537 583 .. 0.82 12 ? 4.2 0.1 0.14 82 8 38 .. 585 617 .. 577 623 .. 0.80 13 ? 3.7 0.0 0.18 1.1e+02 8 41 .. 665 700 .. 657 703 .. 0.83 14 ? 0.6 0.0 1.8 1.1e+03 3 35 .. 699 732 .. 697 738 .. 0.84 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 8 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeG..lGd 36 d k++++ ek l ++ r +eG +G+ FUN_002331-T1 65 DFRKAIEYHEKHLEIAIEVGDRVGEGnaYGN 95 88899******99999999999999833344 PP == domain 2 score: -1.8 bits; conditional E-value: 9.8 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeG 33 d k++++ ek l ++ r +eG FUN_002331-T1 104 DDFQKAIEYHEKHLEIVIEVGNRVGEG 130 4899********999999999999998 PP == domain 3 score: 0.5 bits; conditional E-value: 1.9 Bleomycin_resist_prot_dom 3 vyftkdmdktlkWfekilGWsGdivarddeGlGdyG 38 y d k++++ ek l ++ r +eG yG FUN_002331-T1 180 HYSVGDFRKAIEYHEKNLEIAIEVGNRVGEGN-AYG 214 57788999*******************99994.233 PP == domain 4 score: -1.5 bits; conditional E-value: 7.8 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGlGdyG 38 d k+++ ek l s ++ r eG G FUN_002331-T1 224 VDFQKAIECHEKHLEISIEVGNRVKEGSAY-G 254 6999*************9999999999543.3 PP == domain 5 score: 1.3 bits; conditional E-value: 1.1 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGl..GdyGcvf 41 d+ k++++ ek l ++ r ++G+ G++G v+ FUN_002331-T1 265 DLRKAIEYHEKHLEIAIEVGHRAGQGMayGNFGTVY 300 899*******************99996448999987 PP == domain 6 score: 5.9 bits; conditional E-value: 0.039 Bleomycin_resist_prot_dom 1 Gavyftk.dmdktlkWfekilGWsGdivarddeGlGdy 37 G+vy + d k+++++ek l ++ rd eG y FUN_002331-T1 297 GTVYQSLgDFRKAIEYYEKCLEITKEVGDRDREGS-VY 333 6788764499***********************93.34 PP == domain 7 score: 1.2 bits; conditional E-value: 1.1 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGlGdyG 38 d+ k++++ ek l ++ r +eG+ G FUN_002331-T1 344 GDLRKAIEYHEKHLEIAIEVGDRVGEGIAYGG 375 5999***********************97555 PP == domain 8 score: -1.7 bits; conditional E-value: 9.5 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdy 37 d k++++ ek l ++ r +eG y FUN_002331-T1 385 DFRKAIEYHEKHLEIAIEVGDRVGEGS-AY 413 88999******9999999999999983.33 PP == domain 9 score: 0.1 bits; conditional E-value: 2.6 Bleomycin_resist_prot_dom 10 dktlkWfekilGWsGdivarddeG 33 k+++++ek l ++ rd+eG FUN_002331-T1 427 RKAIEYLEKSLETAIEVGNRDGEG 450 5899*******************9 PP == domain 10 score: -0.0 bits; conditional E-value: 2.7 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++k+ ek l +i r +eG yG FUN_002331-T1 505 DFRKAIKYHEKRLEIAIEISDRIGEGK-AYG 534 889*******************99994.344 PP == domain 11 score: 4.6 bits; conditional E-value: 0.1 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdy 37 d k++++ ek l s ++ rd+eG FUN_002331-T1 545 DFRKAIEYHEKCLEISIEVGDRDEEGRAYG 574 889**********************96533 PP == domain 12 score: 4.2 bits; conditional E-value: 0.14 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeG..lGdyG 38 d k++++ ek l ++ rd+eG +G+ G FUN_002331-T1 585 DHRKAIEYHEKCLEITKEVGDRDGEGrtYGNLG 617 7789*********************94445555 PP == domain 13 score: 3.7 bits; conditional E-value: 0.18 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeG..lGdyGcvf 41 d k++++ ek l ++ rd+eG +G+ G v+ FUN_002331-T1 665 DHRKAIEYHEKRLEIAIEVDDRDGEGnaYGNLGYVY 700 77899********************95567777665 PP == domain 14 score: 0.6 bits; conditional E-value: 1.8 Bleomycin_resist_prot_dom 3 vyftk.dmdktlkWfekilGWsGdivarddeGlG 35 vy + d k++++ ek l ++ r eG+ FUN_002331-T1 699 VYQSLgDFRKAIEYHEKCLEITIEVGNRAAEGMS 732 666533999**********************986 PP >> DUF3856 Domain of Unknown Function (DUF3856) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.1 0.94 5.7e+02 55 83 .. 50 78 .. 5 111 .. 0.66 2 ? 2.4 0.2 0.33 2e+02 63 97 .. 91 125 .. 47 170 .. 0.54 3 ? 1.0 0.1 0.86 5.3e+02 9 82 .. 132 197 .. 126 215 .. 0.63 4 ? 0.1 0.0 1.6 9.9e+02 56 82 .. 211 237 .. 169 249 .. 0.62 5 ? 0.1 0.0 1.7 1e+03 12 41 .. 215 242 .. 205 285 .. 0.53 6 ? 3.1 0.0 0.19 1.2e+02 23 83 .. 304 358 .. 290 371 .. 0.81 7 ? 2.1 0.2 0.41 2.5e+02 55 83 .. 370 398 .. 347 436 .. 0.79 8 ? 2.6 0.2 0.29 1.7e+02 49 82 .. 405 437 .. 371 482 .. 0.59 9 ? 0.2 0.0 1.6 9.6e+02 57 82 .. 492 517 .. 456 529 .. 0.69 10 ? 6.9 0.2 0.014 8.3 8 99 .. 531 613 .. 525 653 .. 0.71 11 ? 2.9 0.1 0.22 1.3e+02 10 86 .. 573 641 .. 567 696 .. 0.65 12 ! 10.0 0.1 0.0014 0.86 23 98 .. 704 775 .. 690 807 .. 0.70 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.94 DUF3856 55 alchaglsealvklgrfeealhsaekalr 83 + +l a+ lg f +a++ ek l+ FUN_002331-T1 50 GNAYGSLGSAYRSLGDFRKAIEYHEKHLE 78 34566777777777777777776666554 PP == domain 2 score: 2.4 bits; conditional E-value: 0.33 DUF3856 63 ealvklgrfeealhsaekalryfnrrGelnqdeGk 97 +a+ +lg+ ++l+ +ka++y ++ e+ + G FUN_002331-T1 91 NAYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEVGN 125 34444444444444444444444444444444443 PP == domain 3 score: 1.0 bits; conditional E-value: 0.86 DUF3856 9 aylalsdaerqlrageyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekal 82 ay +l a + l g++++a+e ++ le++ d +G + + +a++ +g f +a++ ek l FUN_002331-T1 132 AYRSLGIAYQSL--GDFRKASEYHKKHLEIAIE-----VGDRDGQ-GRAYGNIGNAHYSVGDFRKAIEYHEKNL 197 666666666655..7799999999999998654.....3455553.3456667777777777777776555544 PP == domain 4 score: 0.1 bits; conditional E-value: 1.6 DUF3856 56 lchaglsealvklgrfeealhsaekal 82 + l +a+ l f++a++ ek l FUN_002331-T1 211 NAYGNLGNAYNSLVDFQKAIECHEKHL 237 345666777777777777777666665 PP == domain 5 score: 0.1 bits; conditional E-value: 1.7 DUF3856 12 alsdaerqlrageyeeaaescrralevsrt 41 l +a + l+ ++++a e + le+s FUN_002331-T1 215 NLGNAYNSLV--DFQKAIECHEKHLEISIE 242 4444444443..244555555555555433 PP == domain 6 score: 3.1 bits; conditional E-value: 0.19 DUF3856 23 geyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekalr 83 g++++a e + + le+++ + d eG + l +a++ lg +a++ ek l+ FUN_002331-T1 304 GDFRKAIEYYEKCLEITKEVGDR---DREG---SVYGNLGNAYWSLGDLRKAIEYHEKHLE 358 78999999999999999887654...5666...5799999999999999999998888775 PP == domain 7 score: 2.1 bits; conditional E-value: 0.41 DUF3856 55 alchaglsealvklgrfeealhsaekalr 83 + + gl +a+ lg f +a++ ek l+ FUN_002331-T1 370 GIAYGGLGNAYQSLGDFRKAIEYHEKHLE 398 56788899999999999999888877665 PP == domain 8 score: 2.6 bits; conditional E-value: 0.29 DUF3856 49 dyeGfdalchaglsealvklgrfeealhsaekal 82 d G + + l +a+ lg f +a++ ek+l FUN_002331-T1 405 DRVG-EGSAYGNLGNAYQSLGYFRKAIEYLEKSL 437 3333.23345666666666666666665444444 PP == domain 9 score: 0.2 bits; conditional E-value: 1.6 DUF3856 57 chaglsealvklgrfeealhsaekal 82 + l +a+ lg f +a++ ek l FUN_002331-T1 492 AYGNLGNAYKSLGDFRKAIKYHEKRL 517 35556666666666666666655544 PP == domain 10 score: 6.9 bits; conditional E-value: 0.014 DUF3856 8 qaylalsdaerqlrageyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekalryfnrrGelnqdeGklw 99 +ay +l +a r l g++++a e + le+s + d eG + gl +a+ lg + +a++ ek+l+ G+ eG+ + FUN_002331-T1 531 KAYGSLGNAYRSL--GDFRKAIEYHEKCLEISIEVGDR---DEEG---RAYGGLGNAYQSLGDHRKAIEYHEKCLEITKEVGDR-DGEGRTY 613 6888888888877..78999999999999999777643...5566...468999999999999999999999999887777764.3455554 PP == domain 11 score: 2.9 bits; conditional E-value: 0.22 DUF3856 10 ylalsdaerqlrageyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekalryfn 86 y l +a + l g++++a e + le+++ + d +G + + l a+ lg + +a+ s ek+l+ FUN_002331-T1 573 YGGLGNAYQSL--GDHRKAIEYHEKCLEITKEV-----GDRDG-EGRTYGNLGSAYDSLGDHRKAIYSLEKCLEITK 641 44444444444..44556666666666665433.....34444.344667777777777777777777777776554 PP == domain 12 score: 10.0 bits; conditional E-value: 0.0014 DUF3856 23 geyeeaaescrralevsrtipaeeafdyeGfdalchaglsealvklgrfeealhsaekalryfnr.rGeln.qdeGkl 98 g++++a e + le++ + + + h + + ++ lg+fe+al+ + a++ fn r l+ +d+ k+ FUN_002331-T1 704 GDFRKAIEYHEKCLEITIEVGN------RAAEGMSHHNIGQGYFSLGQFENALDKFDSAVKVFNTlRSFLKsEDNWKI 775 4566666666666666544443......344678999***************************73444441344454 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 6.1 3.7e+03 14 28 .. 25 39 .. 21 43 .. 0.85 2 ? 0.9 0.0 1.1 6.9e+02 5 27 .. 56 78 .. 54 82 .. 0.86 3 ? 1.8 0.0 0.6 3.6e+02 5 27 .. 96 118 .. 94 123 .. 0.87 4 ? 2.4 0.0 0.4 2.4e+02 5 27 .. 176 198 .. 174 208 .. 0.88 5 ? 5.1 0.0 0.059 36 8 30 .. 299 321 .. 295 327 .. 0.79 6 ? -0.9 0.0 4.2 2.6e+03 5 27 .. 336 358 .. 332 362 .. 0.84 7 ? 3.1 0.5 0.23 1.4e+02 5 28 .. 376 399 .. 374 440 .. 0.61 8 ? -0.8 0.0 3.7 2.3e+03 5 29 .. 456 480 .. 451 484 .. 0.71 9 ? 1.7 0.0 0.63 3.9e+02 5 27 .. 496 518 .. 494 524 .. 0.87 10 ? 2.1 0.0 0.47 2.9e+02 5 28 .. 536 559 .. 534 563 .. 0.87 11 ? 1.5 0.0 0.74 4.5e+02 5 30 .. 576 601 .. 575 604 .. 0.88 12 ? -2.0 0.0 8.7 5.3e+03 6 27 .. 657 678 .. 656 682 .. 0.79 13 ? 0.7 0.0 1.3 8.1e+02 12 29 .. 703 720 .. 695 768 .. 0.67 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 6.1 ARM_TT21_4th 14 qYkkAinYYeaalks 28 +++kAi+Y e lk FUN_002331-T1 25 DFRKAIEYHERHLKV 39 699******998885 PP == domain 2 score: 0.9 bits; conditional E-value: 1.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G a+ +++kAi+Y e+ l+ FUN_002331-T1 56 LGSAYRSLGDFRKAIEYHEKHLE 78 6889999999********99876 PP == domain 3 score: 1.8 bits; conditional E-value: 0.6 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002331-T1 96 LGNAYDSLDDFQKAIEYHEKHLE 118 799999999*********98765 PP == domain 4 score: 2.4 bits; conditional E-value: 0.4 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 iG+a +++kAi+Y e+ l+ FUN_002331-T1 176 IGNAHYSVGDFRKAIEYHEKNLE 198 899999999*********99876 PP == domain 5 score: 5.1 bits; conditional E-value: 0.059 ARM_TT21_4th 8 alvktHqYkkAinYYeaalksse 30 + +++kAi+YYe+ l++++ FUN_002331-T1 299 VYQSLGDFRKAIEYYEKCLEITK 321 55566689*********998765 PP == domain 6 score: -0.9 bits; conditional E-value: 4.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ + +kAi+Y e+ l+ FUN_002331-T1 336 LGNAYWSLGDLRKAIEYHEKHLE 358 789999999999*****998776 PP == domain 7 score: 3.1 bits; conditional E-value: 0.23 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ l++ FUN_002331-T1 376 LGNAYQSLGDFRKAIEYHEKHLEI 399 588888888888888888877654 PP == domain 8 score: -0.8 bits; conditional E-value: 3.7 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ + +kAi+Y e+ l+++ FUN_002331-T1 456 LGNAYDSLGDLRKAIDYHEKCLEIT 480 5666666667788888888877765 PP == domain 9 score: 1.7 bits; conditional E-value: 0.63 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002331-T1 496 LGNAYKSLGDFRKAIKYHEKRLE 518 799999999*********98776 PP == domain 10 score: 2.1 bits; conditional E-value: 0.47 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ l++ FUN_002331-T1 536 LGNAYRSLGDFRKAIEYHEKCLEI 559 699999999**********98876 PP == domain 11 score: 1.5 bits; conditional E-value: 0.74 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++++ FUN_002331-T1 576 LGNAYQSLGDHRKAIEYHEKCLEITK 601 6999999999*********9998765 PP == domain 12 score: -2.0 bits; conditional E-value: 8.7 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G+a+ +++kAi+Y e+ l+ FUN_002331-T1 657 GNAYDSLGDHRKAIEYHEKRLE 678 77777777899*****998765 PP == domain 13 score: 0.7 bits; conditional E-value: 1.3 ARM_TT21_4th 12 tHqYkkAinYYeaalkss 29 +++kAi+Y e+ l+++ FUN_002331-T1 703 LGDFRKAIEYHEKCLEIT 720 557999999999988754 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.0 0.0 0.19 1.2e+02 1 15 [. 57 71 .. 57 75 .. 0.94 2 ? 0.3 0.2 1.3 8e+02 2 38 .. 91 100 .. 90 115 .. 0.52 3 ? 1.2 0.1 0.68 4.1e+02 30 42 .] 132 144 .. 131 144 .. 0.91 4 ? 0.9 0.1 0.85 5.2e+02 1 14 [. 177 190 .. 171 199 .. 0.69 5 ? 0.6 0.1 1.1 6.7e+02 31 38 .. 213 220 .. 210 239 .. 0.59 6 ? 6.1 0.1 0.02 12 1 15 [. 257 271 .. 257 275 .. 0.96 7 ? 4.8 0.1 0.054 33 1 24 [. 297 320 .. 297 322 .. 0.88 8 ? 3.8 0.1 0.11 66 33 42 .] 335 344 .. 331 352 .. 0.63 9 ? 1.6 0.3 0.51 3.1e+02 1 15 [. 377 391 .. 372 393 .. 0.74 10 ? 2.6 0.6 0.25 1.5e+02 30 42 .] 412 424 .. 411 424 .. 0.90 11 ? 0.0 0.0 1.6 1e+03 1 15 [. 457 471 .. 455 481 .. 0.81 12 ? 3.7 0.2 0.12 72 1 14 [. 497 510 .. 491 512 .. 0.66 13 ? 6.4 0.0 0.017 10 1 15 [. 537 551 .. 537 560 .. 0.86 14 ? 1.9 0.1 0.42 2.5e+02 1 14 [. 577 590 .. 571 601 .. 0.66 15 ? 1.9 0.0 0.44 2.7e+02 1 24 [. 617 640 .. 617 642 .. 0.90 16 ? -0.8 0.0 3 1.8e+03 1 15 [. 657 671 .. 657 684 .. 0.92 17 ? 2.4 0.2 0.3 1.8e+02 29 42 .] 691 704 .. 689 711 .. 0.89 18 ! 7.7 0.0 0.0066 4 1 22 [. 737 758 .. 737 760 .. 0.90 Alignments for each domain: == domain 1 score: 3.0 bits; conditional E-value: 0.19 TPR_11 1 GdayyeqGkyeeAie 15 G ay+++G++ +Aie FUN_002331-T1 57 GSAYRSLGDFRKAIE 71 89************7 PP == domain 2 score: 0.3 bits; conditional E-value: 1.3 TPR_11 2 dayyeqGkyeeAieaYkkAlkldPdnaeayynLGlay 38 + ay nLG+ay FUN_002331-T1 91 N---------------------------AYGNLGNAY 100 4...........................444555554 PP == domain 3 score: 1.2 bits; conditional E-value: 0.68 TPR_11 30 ayynLGlayykqG 42 ay LG ay+ +G FUN_002331-T1 132 AYRSLGIAYQSLG 144 9*********998 PP == domain 4 score: 0.9 bits; conditional E-value: 0.85 TPR_11 1 GdayyeqGkyeeAi 14 G+a y+ G++ +Ai FUN_002331-T1 177 GNAHYSVGDFRKAI 190 56666666666666 PP == domain 5 score: 0.6 bits; conditional E-value: 1.1 TPR_11 31 yynLGlay 38 y nLG+ay FUN_002331-T1 213 YGNLGNAY 220 55555555 PP == domain 6 score: 6.1 bits; conditional E-value: 0.02 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002331-T1 257 GNAYRSLGDLRKAIE 271 9*************7 PP == domain 7 score: 4.8 bits; conditional E-value: 0.054 TPR_11 1 GdayyeqGkyeeAieaYkkAlkld 24 G +y ++G++ +Aie Y+k l+++ FUN_002331-T1 297 GTVYQSLGDFRKAIEYYEKCLEIT 320 567889*************99997 PP == domain 8 score: 3.8 bits; conditional E-value: 0.11 TPR_11 33 nLGlayykqG 42 nLG+ay+ +G FUN_002331-T1 335 NLGNAYWSLG 344 6666666655 PP == domain 9 score: 1.6 bits; conditional E-value: 0.51 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002331-T1 377 GNAYQSLGDFRKAIE 391 777777777777775 PP == domain 10 score: 2.6 bits; conditional E-value: 0.25 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002331-T1 412 AYGNLGNAYQSLG 424 899*******998 PP == domain 11 score: 0.0 bits; conditional E-value: 1.6 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Ai FUN_002331-T1 457 GNAYDSLGDLRKAID 471 888999999999885 PP == domain 12 score: 3.7 bits; conditional E-value: 0.12 TPR_11 1 GdayyeqGkyeeAi 14 G+ay ++G++ +Ai FUN_002331-T1 497 GNAYKSLGDFRKAI 510 66666666666666 PP == domain 13 score: 6.4 bits; conditional E-value: 0.017 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002331-T1 537 GNAYRSLGDFRKAIE 551 9*************8 PP == domain 14 score: 1.9 bits; conditional E-value: 0.42 TPR_11 1 GdayyeqGkyeeAi 14 G+ay ++G+ +Ai FUN_002331-T1 577 GNAYQSLGDHRKAI 590 56666666666666 PP == domain 15 score: 1.9 bits; conditional E-value: 0.44 TPR_11 1 GdayyeqGkyeeAieaYkkAlkld 24 G ay ++G+ +Ai +++k l+++ FUN_002331-T1 617 GSAYDSLGDHRKAIYSLEKCLEIT 640 788999*************99997 PP == domain 16 score: -0.8 bits; conditional E-value: 3 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G+ +Aie FUN_002331-T1 657 GNAYDSLGDHRKAIE 671 99999*****99997 PP == domain 17 score: 2.4 bits; conditional E-value: 0.3 TPR_11 29 eayynLGlayykqG 42 +ay nLG++y+ +G FUN_002331-T1 691 NAYGNLGYVYQSLG 704 68899999999887 PP == domain 18 score: 7.7 bits; conditional E-value: 0.0066 TPR_11 1 GdayyeqGkyeeAieaYkkAlk 22 G+ y+++G++e+A+ ++ A+k FUN_002331-T1 737 GQGYFSLGQFENALDKFDSAVK 758 666**************99997 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.2 0.09 55 87 142 .. 60 116 .. 35 236 .. 0.74 2 ? 4.5 0.0 0.024 15 71 142 .. 237 316 .. 195 326 .. 0.68 3 ? 3.0 0.2 0.073 44 209 250 .. 434 475 .. 300 483 .. 0.75 4 ? 3.9 0.1 0.039 24 86 150 .. 499 564 .. 470 676 .. 0.62 5 ? 0.1 0.0 0.56 3.4e+02 86 142 .. 659 716 .. 621 730 .. 0.61 6 ? -0.0 0.0 0.58 3.6e+02 407 450 .. 734 777 .. 709 781 .. 0.81 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.09 TPR_IF140-IFT172 87 ydllnklyqasgkwdkaleva.ekkdrihlrktyynyakhleakgdieeaiklyeks 142 y l ++ +a + +k le+a e dr+ ++y n + ++ +d+++ai+++ek FUN_002331-T1 60 YRSLGDFRKAIEYHEKHLEIAiEVGDRVGEGNAYGNLGNAYDSLDDFQKAIEYHEKH 116 444445555555555555555233477777777777777777777777777777664 PP == domain 2 score: 4.5 bits; conditional E-value: 0.024 TPR_IF140-IFT172 71 Lglldeaekllksckrydllnklyqasgkwdkalevaekkdrihlr........ktyynyakhleakgdieeaiklyeks 142 L++ e + +k+ + y l + y++ g + ka+e ek+ i + +y n+ + ++ gd+++ai++yek+ FUN_002331-T1 237 LEISIEVGNRVKEGSAYGGLGNAYRSLGDLRKAIEYHEKHLEIAIEvghragqgMAYGNFGTVYQSLGDFRKAIEYYEKC 316 55555555556666666666666666666666666666654443321111111157788999999999999999999987 PP == domain 3 score: 3.0 bits; conditional E-value: 0.073 TPR_IF140-IFT172 209 ledlekaaelanetgdkaacyhlarqyenadeikeaihfftr 250 + le a e+ n g+ c l+ y++ +++++ai+++ + FUN_002331-T1 434 EKSLETAIEVGNRDGEGRTCANLGNAYDSLGDLRKAIDYHEK 475 345677777777777777777777777777777777777655 PP == domain 4 score: 3.9 bits; conditional E-value: 0.039 TPR_IF140-IFT172 86 rydllnklyqasgkwdkaleva.ekkdrihlrktyynyakhleakgdieeaiklyeksethrfevP 150 y l ++ +a + +k le+a e +dri k+y + + gd+++ai+++ek+ ev FUN_002331-T1 499 AYKSLGDFRKAIKYHEKRLEIAiEISDRIGEGKAYGSLGNAYRSLGDFRKAIEYHEKCLEISIEVG 564 345555555555555566666634589999999999999999999999999999999977666665 PP == domain 5 score: 0.1 bits; conditional E-value: 0.56 TPR_IF140-IFT172 86 rydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 yd l + +a + +k le+a + dr ++y n + ++ gd+++ai+++ek+ FUN_002331-T1 659 AYDSLGDHRKAIEYHEKRLEIAIEvDDRDGEGNAYGNLGYVYQSLGDFRKAIEYHEKC 716 3444444444444444444555331455555667777777777778888888777776 PP == domain 6 score: -0.0 bits; conditional E-value: 0.58 TPR_IF140-IFT172 407 ekvaevclkqenyhlatkkftqaGdkvkamkaLlksGdtekiif 450 +++++ ++ ++++ a kf a + ++ ++++lks d ki f FUN_002331-T1 734 HNIGQGYFSLGQFENALDKFDSAVKVFNTLRSFLKSEDNWKINF 777 45667777788999999999999999999999999999988865 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 1.7 1e+03 3 20 .. 132 149 .. 130 151 .. 0.88 2 ? -0.1 0.0 4.9 3e+03 3 20 .. 252 269 .. 250 270 .. 0.87 3 ? 3.6 0.0 0.31 1.9e+02 4 20 .. 333 349 .. 330 351 .. 0.87 4 ? 0.2 0.0 3.9 2.4e+03 3 20 .. 372 389 .. 371 390 .. 0.87 5 ? 1.4 0.0 1.7 1e+03 2 20 .. 451 469 .. 450 470 .. 0.90 6 ? 0.4 0.0 3.4 2.1e+03 2 20 .. 491 509 .. 490 509 .. 0.89 7 ? 2.6 0.1 0.68 4.1e+02 2 20 .. 571 589 .. 570 591 .. 0.90 8 ? 0.5 0.0 3.2 1.9e+03 3 20 .. 692 709 .. 690 710 .. 0.89 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 1.7 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a++ lGd+ A FUN_002331-T1 132 AYRSLGIAYQSLGDFRKA 149 7889**********9887 PP == domain 2 score: -0.1 bits; conditional E-value: 4.9 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGdl A FUN_002331-T1 252 AYGGLGNAYRSLGDLRKA 269 7789**********9877 PP == domain 3 score: 3.6 bits; conditional E-value: 0.31 TPR_4 4 llaLArallalGdldeA 20 + +L+ a++ lGdl A FUN_002331-T1 333 YGNLGNAYWSLGDLRKA 349 679**********9887 PP == domain 4 score: 0.2 bits; conditional E-value: 3.9 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002331-T1 372 AYGGLGNAYQSLGDFRKA 389 56789*********9877 PP == domain 5 score: 1.4 bits; conditional E-value: 1.7 TPR_4 2 rallaLArallalGdldeA 20 r++++L+ a+ lGdl A FUN_002331-T1 451 RTCANLGNAYDSLGDLRKA 469 7899***********9877 PP == domain 6 score: 0.4 bits; conditional E-value: 3.4 TPR_4 2 rallaLArallalGdldeA 20 ra+ +L+ a+ lGd+ A FUN_002331-T1 491 RAYGNLGNAYKSLGDFRKA 509 8999***********9876 PP == domain 7 score: 2.6 bits; conditional E-value: 0.68 TPR_4 2 rallaLArallalGdldeA 20 ra+ +L+ a++ lGd+ A FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKA 589 79999***********887 PP == domain 8 score: 0.5 bits; conditional E-value: 3.2 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ +++ lGd+ A FUN_002331-T1 692 AYGNLGYVYQSLGDFRKA 709 6789**********9877 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.0 6.9 4.2e+03 8 45 .. 49 86 .. 45 89 .. 0.86 2 ? 1.3 0.0 0.48 2.9e+02 4 45 .. 125 166 .. 122 169 .. 0.87 3 ? -1.9 0.0 4.6 2.8e+03 11 45 .. 172 206 .. 166 209 .. 0.87 4 ? 0.6 0.0 0.81 4.9e+02 4 45 .. 245 286 .. 242 291 .. 0.89 5 ? 1.3 0.0 0.49 3e+02 10 49 .. 291 330 .. 282 337 .. 0.85 6 ? 3.0 0.0 0.14 86 6 45 .. 407 446 .. 402 453 .. 0.90 7 ? -1.1 0.0 2.6 1.6e+03 12 46 .. 453 487 .. 448 492 .. 0.87 8 ? -0.7 0.0 1.9 1.2e+03 5 43 .. 526 564 .. 522 570 .. 0.83 9 ? -2.3 0.0 6 3.7e+03 8 44 .. 569 605 .. 562 606 .. 0.83 10 ? -0.8 0.0 2.1 1.3e+03 8 45 .. 689 726 .. 683 731 .. 0.86 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 6.9 DUF6377 8 enaallkLaellyeegdierAykYikvaledakfynar 45 e a +L++ + gd+++A +Y + le a +++r FUN_002331-T1 49 EGNAYGSLGSAYRSLGDFRKAIEYHEKHLEIAIEVGDR 86 677888999999999*********99999998888776 PP == domain 2 score: 1.3 bits; conditional E-value: 0.48 DUF6377 4 satkenaallkLaellyeegdierAykYikvaledakfynar 45 + + e +a ++L+ + gd+++A++Y k le a +++r FUN_002331-T1 125 NRVGEGSAYRSLGIAYQSLGDFRKASEYHKKHLEIAIEVGDR 166 5677999***********************999988877765 PP == domain 3 score: -1.9 bits; conditional E-value: 4.6 DUF6377 11 allkLaellyeegdierAykYikvaledakfynar 45 a ++++ y gd+++A +Y + le a +++r FUN_002331-T1 172 AYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEVGNR 206 566788999***************99999988887 PP == domain 4 score: 0.6 bits; conditional E-value: 0.81 DUF6377 4 satkenaallkLaellyeegdierAykYikvaledakfynar 45 + +ke +a L++ + gd+++A +Y + le a ++ r FUN_002331-T1 245 NRVKEGSAYGGLGNAYRSLGDLRKAIEYHEKHLEIAIEVGHR 286 7899*************************9999988887766 PP == domain 5 score: 1.3 bits; conditional E-value: 0.49 DUF6377 10 aallkLaellyeegdierAykYikvaledakfynarlRkl 49 +a + ++++ gd+++A +Y + +le +k +++r R+ FUN_002331-T1 291 MAYGNFGTVYQSLGDFRKAIEYYEKCLEITKEVGDRDREG 330 6667777788888*********************999975 PP == domain 6 score: 3.0 bits; conditional E-value: 0.14 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L++ + g +++A +Y++ +le a +++r FUN_002331-T1 407 VGEGSAYGNLGNAYQSLGYFRKAIEYLEKSLETAIEVGNR 446 56788999**************************998887 PP == domain 7 score: -1.1 bits; conditional E-value: 2.6 DUF6377 12 llkLaellyeegdierAykYikvaledakfynarl 46 +L++ + gd+++A Y + +le +k +++r+ FUN_002331-T1 453 CANLGNAYDSLGDLRKAIDYHEKCLEITKEVGDRF 487 56899999999***************999988875 PP == domain 8 score: -0.7 bits; conditional E-value: 1.9 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfyn 43 + e a +L++ + gd+++A +Y + +le ++ FUN_002331-T1 526 RIGEGKAYGSLGNAYRSLGDFRKAIEYHEKCLEISIEVG 564 5678889999********************999766665 PP == domain 9 score: -2.3 bits; conditional E-value: 6 DUF6377 8 enaallkLaellyeegdierAykYikvaledakfyna 44 e a L++ + gd ++A +Y + +le +k +++ FUN_002331-T1 569 EGRAYGGLGNAYQSLGDHRKAIEYHEKCLEITKEVGD 605 556677789999999*************998887765 PP == domain 10 score: -0.8 bits; conditional E-value: 2.1 DUF6377 8 enaallkLaellyeegdierAykYikvaledakfynar 45 e a +L+ ++ gd+++A +Y + +le + +++r FUN_002331-T1 689 EGNAYGNLGYVYQSLGDFRKAIEYHEKCLEITIEVGNR 726 567888999999999**************988877776 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.17 1e+02 75 107 .. 38 70 .. 10 72 .. 0.80 2 ? -1.8 0.0 8.1 5e+03 82 106 .. 85 109 .. 74 111 .. 0.66 3 ? 2.6 0.0 0.37 2.2e+02 82 107 .. 245 270 .. 206 272 .. 0.86 4 ? 4.0 0.0 0.13 79 74 107 .. 354 390 .. 314 392 .. 0.75 5 ? -0.5 0.0 3.3 2e+03 108 108 .. 471 471 .. 428 512 .. 0.60 6 ? 2.2 0.0 0.49 3e+02 75 108 .. 518 551 .. 504 559 .. 0.82 7 ? -1.7 0.0 8 4.8e+03 88 107 .. 571 590 .. 563 598 .. 0.79 8 ? -1.6 0.0 7.4 4.5e+03 75 106 .. 638 669 .. 618 671 .. 0.80 9 ? 0.9 0.0 1.3 7.7e+02 51 90 .. 1140 1179 .. 1134 1192 .. 0.74 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.17 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 ++++++ +r+g+ +++ +G+++++l ++r++ FUN_002331-T1 38 KVAREVGDRVGEGNAYGSLGSAYRSLGDFRKAI 70 7899999999999999999*******9999985 PP == domain 2 score: -1.8 bits; conditional E-value: 8.1 GGDEF_2 82 rrlggitvriGvGrpveglaglrrS 106 +r+g+ +++ +G+++++l+++ ++ FUN_002331-T1 85 DRVGEGNAYGNLGNAYDSLDDFQKA 109 4555555566678888888888776 PP == domain 3 score: 2.6 bits; conditional E-value: 0.37 GGDEF_2 82 rrlggitvriGvGrpveglaglrrSy 107 +r+++ +++ G+G+++++l +lr++ FUN_002331-T1 245 NRVKEGSAYGGLGNAYRSLGDLRKAI 270 5666678999************9985 PP == domain 4 score: 4.0 bits; conditional E-value: 0.13 GGDEF_2 74 e...ellerlrrrlggitvriGvGrpveglaglrrSy 107 e e++ ++ +r+g+ ++ G+G+++++l ++r++ FUN_002331-T1 354 EkhlEIAIEVGDRVGEGIAYGGLGNAYQSLGDFRKAI 390 14557888888899999999**************986 PP == domain 5 score: -0.5 bits; conditional E-value: 3.3 GGDEF_2 108 r 108 FUN_002331-T1 471 D 471 1 PP == domain 6 score: 2.2 bits; conditional E-value: 0.49 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSyr 108 e++ ++++r+g+ ++ +G+++++l ++r++ + FUN_002331-T1 518 EIAIEISDRIGEGKAYGSLGNAYRSLGDFRKAIE 551 77788899999999999999*******9999865 PP == domain 7 score: -1.7 bits; conditional E-value: 8 GGDEF_2 88 tvriGvGrpveglaglrrSy 107 +++ G+G+++++l + r++ FUN_002331-T1 571 RAYGGLGNAYQSLGDHRKAI 590 56778999999998888775 PP == domain 8 score: -1.6 bits; conditional E-value: 7.4 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e+ +++ +r+g+ +++ +G+++++l + r++ FUN_002331-T1 638 EITKEVGDRVGEGSAYGILGNAYDSLGDHRKA 669 67788888888899999999999999998887 PP == domain 9 score: 0.9 bits; conditional E-value: 1.3 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvr 90 +l+a ++ lv+l++ ddea+ e+++r+ ++l++ t++ FUN_002331-T1 1140 AFLAAGARSVLVALWAIDDEAT-MEFMKRFYQHLKEgKTAS 1179 56777788899*******9865.677888888777744444 PP >> DUF386 YhcH/YjgK/YiaL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.4 0.0 0.17 1e+02 17 72 .. 65 120 .. 26 169 .. 0.72 2 ? 3.1 0.0 0.2 1.2e+02 9 73 .. 179 241 .. 172 283 .. 0.83 3 ? -1.1 0.0 4 2.4e+03 19 74 .. 347 362 .. 298 404 .. 0.56 4 ? 2.1 0.0 0.42 2.6e+02 16 71 .. 424 479 .. 412 483 .. 0.83 5 ? -1.1 0.0 4 2.5e+03 17 71 .. 545 599 .. 531 601 .. 0.70 Alignments for each domain: == domain 1 score: 3.4 bits; conditional E-value: 0.17 DUF386 17 klkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiq 72 ++ka+e+ +++ ++e g +g+ + + y++ ++ ++ +E+H+k+++i FUN_002331-T1 65 DFRKAIEYHEKHLEIAIEVGDRVGEGNAYGNLGNAYDSLDDFQKAIEYHEKHLEIV 120 56677777777766777777666666665566666777777777777777777663 PP == domain 2 score: 3.1 bits; conditional E-value: 0.2 DUF386 9 lkryelppklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiqi 73 ++ y ++ka+e+ +++ ++e g+ +g+ + + y++ + ++ +E+H+k+++i i FUN_002331-T1 179 AH-Y-SVGDFRKAIEYHEKNLEIAIEVGNRVGEGNAYGNLGNAYNSLVDFQKAIECHEKHLEISI 241 44.3.337899999999999889999999998888777777888899999999******999976 PP == domain 3 score: -1.1 bits; conditional E-value: 4 DUF386 19 kkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDiqiv 74 +ka +E+H+k+++i i FUN_002331-T1 347 RKA----------------------------------------IEYHEKHLEIAIE 362 333........................................4444444444332 PP == domain 4 score: 2.1 bits; conditional E-value: 0.42 DUF386 16 pklkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDi 71 ++ka+e+l+++ +++e g+ + +g + + + y++ + + + +H+k ++i FUN_002331-T1 424 GYFRKAIEYLEKSLETAIEVGNRDGEGRTCANLGNAYDSLGDLRKAIDYHEKCLEI 479 679*******999999*******999999888888888888888899999998877 PP == domain 5 score: -1.1 bits; conditional E-value: 4 DUF386 17 klkkaleflketdleeleegkyeidgddlfanvqeyetkpkeeaklEvHrkyiDi 71 ++ka+e+ ++ ++e g + +g + + y++ + + +E+H+k ++i FUN_002331-T1 545 DFRKAIEYHEKCLEISIEVGDRDEEGRAYGGLGNAYQSLGDHRKAIEYHEKCLEI 599 5677777776666677777777777777777777777777777888888887766 PP >> DUF6225 Family of unknown function (DUF6225) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 5.1 3.1e+03 15 46 .. 64 95 .. 61 97 .. 0.88 2 ? 0.3 0.0 1.7 1.1e+03 12 46 .. 181 215 .. 178 235 .. 0.90 3 ? 0.1 0.0 1.9 1.2e+03 15 50 .. 264 299 .. 260 311 .. 0.88 4 ? 2.9 0.0 0.25 1.5e+02 11 44 .. 340 373 .. 336 377 .. 0.90 5 ? -2.1 0.0 9.6 5.9e+03 15 45 .. 384 414 .. 381 416 .. 0.86 6 ? -1.9 0.0 8 4.9e+03 18 47 .. 667 696 .. 663 715 .. 0.77 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 5.1 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyee 46 g R+a++ + i ++v d G++++y + FUN_002331-T1 64 GDFRKAIEYHEKHLEIAIEVGDRVGEGNAYGN 95 678999999999999************99975 PP == domain 2 score: 0.3 bits; conditional E-value: 1.7 DUF6225 12 WtagrLRealkgLPDdtPihvgvaddPGdfdgyee 46 +++g R+a++ ++ i ++v + G++++y + FUN_002331-T1 181 YSVGDFRKAIEYHEKNLEIAIEVGNRVGEGNAYGN 215 578999************************99976 PP == domain 3 score: 0.1 bits; conditional E-value: 1.9 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgyeeyvlv 50 g LR+a++ + i ++v G++ +y ++ v FUN_002331-T1 264 GDLRKAIEYHEKHLEIAIEVGHRAGQGMAYGNFGTV 299 789**************************9998766 PP == domain 4 score: 2.9 bits; conditional E-value: 0.25 DUF6225 11 vWtagrLRealkgLPDdtPihvgvaddPGdfdgy 44 W+ g LR+a++ + i ++v d G++ +y FUN_002331-T1 340 YWSLGDLRKAIEYHEKHLEIAIEVGDRVGEGIAY 373 5*************************99998777 PP == domain 5 score: -2.1 bits; conditional E-value: 9.6 DUF6225 15 grLRealkgLPDdtPihvgvaddPGdfdgye 45 g R+a++ + i ++v d G++ +y FUN_002331-T1 384 GDFRKAIEYHEKHLEIAIEVGDRVGEGSAYG 414 678999999999999**********999996 PP == domain 6 score: -1.9 bits; conditional E-value: 8 DUF6225 18 RealkgLPDdtPihvgvaddPGdfdgyeey 47 R+a++ + i ++v d G++++y + FUN_002331-T1 667 RKAIEYHEKRLEIAIEVDDRDGEGNAYGNL 696 666666667778999999999999999864 PP >> DHR-2_Lobe_A DHR-2, Lobe A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 6.1 3.7e+03 101 149 .. 219 267 .. 209 271 .. 0.71 2 ? -0.8 0.0 3.9 2.4e+03 108 147 .. 306 345 .. 296 351 .. 0.70 3 ? 4.8 0.0 0.074 45 108 152 .. 466 510 .. 421 512 .. 0.85 4 ? 0.6 0.0 1.4 8.7e+02 110 148 .. 548 586 .. 534 592 .. 0.85 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 6.1 DHR-2_Lobe_A 101 lleeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaely 149 +++ +d+ k e++E e++ ++ ++ +Y l ++++ l +l FUN_002331-T1 219 AYNSLVDFQKAIECHEKHLEISIEVGNRVKEGSAYGGLGNAYRSLGDLR 267 4566677777777777777777777777777777777777777777665 PP == domain 2 score: -0.8 bits; conditional E-value: 3.9 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklae 147 + k e+yE + e+ k++ + Y +l +++ l + FUN_002331-T1 306 FRKAIEYYEKCLEITKEVGDRDREGSVYGNLGNAYWSLGD 345 5556699999999999987777777777777766666555 PP == domain 3 score: 4.8 bits; conditional E-value: 0.074 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + k +++E + e+ k++ + + r+Y +l +++k l ++ + i FUN_002331-T1 466 LRKAIDYHEKCLEITKEVGDRFVEGRAYGNLGNAYKSLGDFRKAI 510 5566689*******************************9987776 PP == domain 4 score: 0.6 bits; conditional E-value: 1.4 DHR-2_Lobe_A 110 kkaelyElaielyklllpiyekkrdYkklseihkklael 148 k e++E + e++ ++ e+ r+Y l ++++ l + FUN_002331-T1 548 KAIEYHEKCLEISIEVGDRDEEGRAYGGLGNAYQSLGDH 586 55699****************************998765 PP >> Spectrin Spectrin repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.57 3.5e+02 30 67 .. 90 127 .. 62 141 .. 0.76 2 ? -1.7 0.0 9.5 5.8e+03 24 67 .. 163 207 .. 146 216 .. 0.72 3 ? 2.6 0.0 0.42 2.6e+02 6 71 .. 426 491 .. 421 502 .. 0.88 4 ? -0.3 0.0 3.6 2.2e+03 19 67 .. 478 527 .. 468 535 .. 0.76 5 ? -1.1 0.0 6.3 3.8e+03 8 65 .. 548 605 .. 542 649 .. 0.69 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.57 Spectrin 30 gkdlesvqallkkhkaleaelaaqqervealnelaekl 67 g+ + ++ + + ++++++ ++ +++++e + e+++++ FUN_002331-T1 90 GNAYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEVGNRV 127 677778888889999****************9999987 PP == domain 2 score: -1.7 bits; conditional E-value: 9.5 Spectrin 24 lssedl.gkdlesvqallkkhkaleaelaaqqervealnelaekl 67 + ++d g+ + ++ + + ++++ ++ +++++e e+++++ FUN_002331-T1 163 VGDRDGqGRAYGNIGNAHYSVGDFRKAIEYHEKNLEIAIEVGNRV 207 54555557777788888888889999*******999999988876 PP == domain 3 score: 2.6 bits; conditional E-value: 0.42 Spectrin 6 fardaddlesWieekeellssedlgkdlesvqallkkhkaleaelaaqqervealnelaeklieeg 71 f + ++ le+ +e + e + + g++ +++ + + + +l++ ++ +++ +e +e++++++e FUN_002331-T1 426 FRKAIEYLEKSLETAIEVGNRDGEGRTCANLGNAYDSLGDLRKAIDYHEKCLEITKEVGDRFVEGR 491 778888899999999998888888***********************************9997765 PP == domain 4 score: -0.3 bits; conditional E-value: 3.6 Spectrin 19 ekeellssedl.gkdlesvqallkkhkaleaelaaqqervealnelaekl 67 e+ +++ ++ + g+ + ++ + k + ++++ ++ +++r+e e+++++ FUN_002331-T1 478 EITKEVGDRFVeGRAYGNLGNAYKSLGDFRKAIKYHEKRLEIAIEISDRI 527 444555566666888999999999999*************9988887776 PP == domain 5 score: -1.1 bits; conditional E-value: 6.3 Spectrin 8 rdaddlesWieekeellssedlgkdlesvqallkkhkaleaelaaqqervealnelae 65 + ++ e+++e e ++ g+ + ++ + + + ++++ ++ +++ +e +e+++ FUN_002331-T1 548 KAIEYHEKCLEISIEVGDRDEEGRAYGGLGNAYQSLGDHRKAIEYHEKCLEITKEVGD 605 5555555555555555555555777777777777777777777777777777666654 PP >> Urocanase_N Urocanase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 2.6 1.6e+03 34 61 .. 46 73 .. 37 84 .. 0.80 2 ? -0.8 0.0 2.9 1.8e+03 36 62 .. 88 114 .. 68 128 .. 0.80 3 ? -1.8 0.0 5.9 3.6e+03 30 60 .. 202 232 .. 175 239 .. 0.81 4 ? 0.5 0.0 1.2 7.3e+02 29 61 .. 241 273 .. 236 288 .. 0.82 5 ? 0.7 0.0 1 6.1e+02 30 63 .. 282 315 .. 276 324 .. 0.84 6 ? 4.8 0.0 0.056 34 29 62 .. 361 394 .. 348 408 .. 0.87 7 ? 2.0 0.0 0.41 2.5e+02 33 63 .. 405 435 .. 396 442 .. 0.82 8 ? -1.4 0.0 4.6 2.8e+03 36 61 .. 488 513 .. 478 518 .. 0.78 9 ? -1.2 0.0 3.8 2.3e+03 40 62 .. 532 554 .. 518 559 .. 0.82 10 ? 0.1 0.0 1.6 9.7e+02 29 61 .. 561 593 .. 556 602 .. 0.82 11 ? -2.1 0.0 7.6 4.6e+03 29 63 .. 601 635 .. 596 656 .. 0.81 12 ? -2.5 0.0 10 6.1e+03 40 61 .. 692 713 .. 679 718 .. 0.82 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 2.6 Urocanase_N 34 kpeeLvvYGgtGkaarnweqfelivktL 61 + e YG G+a r+ f++ +++ FUN_002331-T1 46 RVGEGNAYGSLGSAYRSLGDFRKAIEYH 73 5555568**************9999875 PP == domain 2 score: -0.8 bits; conditional E-value: 2.9 Urocanase_N 36 eeLvvYGgtGkaarnweqfelivktLk 62 e YG+ G+a + + f++ +++ + FUN_002331-T1 88 GEGNAYGNLGNAYDSLDDFQKAIEYHE 114 55567*************999988754 PP == domain 3 score: -1.8 bits; conditional E-value: 5.9 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivkt 60 ev ++ e YG+ G+a ++ f++ +++ FUN_002331-T1 202 EVGNRVGEGNAYGNLGNAYNSLVDFQKAIEC 232 56666677778********999999988765 PP == domain 4 score: 0.5 bits; conditional E-value: 1.2 Urocanase_N 29 pevaekpeeLvvYGgtGkaarnweqfelivktL 61 ev ++ +e YGg G+a r+ +++ +++ FUN_002331-T1 241 IEVGNRVKEGSAYGGLGNAYRSLGDLRKAIEYH 273 577888888889*********999988887775 PP == domain 5 score: 0.7 bits; conditional E-value: 1 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivktLke 63 ev ++ + + YG+ G++ ++ f++ +++ ++ FUN_002331-T1 282 EVGHRAGQGMAYGNFGTVYQSLGDFRKAIEYYEK 315 66677777789***************99998765 PP == domain 6 score: 4.8 bits; conditional E-value: 0.056 Urocanase_N 29 pevaekpeeLvvYGgtGkaarnweqfelivktLk 62 ev ++ e + YGg G+a ++ f++ +++ + FUN_002331-T1 361 IEVGDRVGEGIAYGGLGNAYQSLGDFRKAIEYHE 394 5788888899****************99998854 PP == domain 7 score: 2.0 bits; conditional E-value: 0.41 Urocanase_N 33 ekpeeLvvYGgtGkaarnweqfelivktLke 63 ++ e YG+ G+a ++ f++ +++L++ FUN_002331-T1 405 DRVGEGSAYGNLGNAYQSLGYFRKAIEYLEK 435 55556668********************986 PP == domain 8 score: -1.4 bits; conditional E-value: 4.6 Urocanase_N 36 eeLvvYGgtGkaarnweqfelivktL 61 e YG+ G+a ++ f++ +k+ FUN_002331-T1 488 VEGRAYGNLGNAYKSLGDFRKAIKYH 513 55557**************9998875 PP == domain 9 score: -1.2 bits; conditional E-value: 3.8 Urocanase_N 40 vYGgtGkaarnweqfelivktLk 62 YG G+a r+ f++ +++ + FUN_002331-T1 532 AYGSLGNAYRSLGDFRKAIEYHE 554 7**************99998865 PP == domain 10 score: 0.1 bits; conditional E-value: 1.6 Urocanase_N 29 pevaekpeeLvvYGgtGkaarnweqfelivktL 61 ev ++ ee YGg G+a ++ +++ +++ FUN_002331-T1 561 IEVGDRDEEGRAYGGLGNAYQSLGDHRKAIEYH 593 577888888889*********999988888775 PP == domain 11 score: -2.1 bits; conditional E-value: 7.6 Urocanase_N 29 pevaekpeeLvvYGgtGkaarnweqfelivktLke 63 +ev ++ e +YG+ G+a + +++ + +L++ FUN_002331-T1 601 KEVGDRDGEGRTYGNLGSAYDSLGDHRKAIYSLEK 635 566777777779*******9999999888888875 PP == domain 12 score: -2.5 bits; conditional E-value: 10 Urocanase_N 40 vYGgtGkaarnweqfelivktL 61 YG+ G + ++ f++ +++ FUN_002331-T1 692 AYGNLGYVYQSLGDFRKAIEYH 713 7**************9999875 PP >> Transferase Transferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1 6.2e+02 273 325 .. 71 123 .. 60 149 .. 0.84 2 ? 3.4 0.0 0.058 35 275 324 .. 193 242 .. 183 287 .. 0.83 3 ? 1.5 0.0 0.22 1.3e+02 273 324 .. 391 442 .. 348 454 .. 0.82 4 ? -1.1 0.0 1.3 7.8e+02 274 317 .. 512 555 .. 501 566 .. 0.82 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivek 325 e +e+ l ia+++ r+ + + GNa+ s +++a e ++ l ++e FUN_002331-T1 71 EYHEKHLEIAIEVGDRVGEGNAYGNLGNAYDSLDDFQKAIEYHEKHLEIVIEV 123 55678999**********************************99999877764 PP == domain 2 score: 3.4 bits; conditional E-value: 0.058 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 +e+ l ia+++ +r+ + + GNa+ s v +++a e ++ l +e FUN_002331-T1 193 HEKNLEIAIEVGNRVGEGNAYGNLGNAYNSLVDFQKAIECHEKHLEISIE 242 56889999999999999999999999999999999999999998876655 PP == domain 3 score: 1.5 bits; conditional E-value: 0.22 Transferase 273 eeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 e +e+ l ia+++ r+ + + GNa++s + +a e l++ l ++e FUN_002331-T1 391 EYHEKHLEIAIEVGDRVGEGSAYGNLGNAYQSLGYFRKAIEYLEKSLETAIE 442 4455788888999999999999999999999999999999988888887766 PP == domain 4 score: -1.1 bits; conditional E-value: 1.3 Transferase 274 eketvlgiavdiRsrlepklpesyfGNallsvvvkstakellse 317 +e+ l ia++i r+ + ++ GNa+ s + +a e ++ FUN_002331-T1 512 YHEKRLEIAIEISDRIGEGKAYGSLGNAYRSLGDFRKAIEYHEK 555 456899***********************999888888777666 PP >> MIT MIT (microtubule interacting and transport) domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 9.3 5.7e+03 14 29 .. 100 115 .. 94 122 .. 0.76 2 ? 4.8 0.0 0.071 43 17 33 .. 303 319 .. 292 328 .. 0.88 3 ? 0.5 0.1 1.6 9.7e+02 17 39 .. 416 438 .. 407 445 .. 0.80 4 ? 1.7 0.0 0.64 3.9e+02 12 32 .. 458 478 .. 450 483 .. 0.86 5 ? -0.6 0.0 3.4 2e+03 18 32 .. 544 558 .. 540 569 .. 0.88 6 ? -1.3 0.0 5.4 3.3e+03 18 32 .. 584 598 .. 580 605 .. 0.86 7 ? -0.2 0.0 2.6 1.6e+03 18 33 .. 704 719 .. 699 727 .. 0.87 8 ? 2.8 0.0 0.3 1.9e+02 18 40 .. 744 767 .. 742 783 .. 0.79 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 9.3 MIT 14 eDnagnyeeAlelYke 29 +D+ ++++A+e+ ++ FUN_002331-T1 100 YDSLDDFQKAIEYHEK 115 6777788888888765 PP == domain 2 score: 4.8 bits; conditional E-value: 0.071 MIT 17 agnyeeAlelYkealel 33 g++ +A+e+Y+++le FUN_002331-T1 303 LGDFRKAIEYYEKCLEI 319 6899**********985 PP == domain 3 score: 0.5 bits; conditional E-value: 1.6 MIT 17 agnyeeAlelYkealelLlqalk 39 gn + l ++++a+e+L + l FUN_002331-T1 416 LGNAYQSLGYFRKAIEYLEKSLE 438 56777778899999999988775 PP == domain 4 score: 1.7 bits; conditional E-value: 0.64 MIT 12 veeDnagnyeeAlelYkeale 32 +D+ g+ +A+++ +++le FUN_002331-T1 458 NAYDSLGDLRKAIDYHEKCLE 478 579****************98 PP == domain 5 score: -0.6 bits; conditional E-value: 3.4 MIT 18 gnyeeAlelYkeale 32 g++ +A+e+ +++le FUN_002331-T1 544 GDFRKAIEYHEKCLE 558 8999*********98 PP == domain 6 score: -1.3 bits; conditional E-value: 5.4 MIT 18 gnyeeAlelYkeale 32 g+ +A+e+ +++le FUN_002331-T1 584 GDHRKAIEYHEKCLE 598 78899*******998 PP == domain 7 score: -0.2 bits; conditional E-value: 2.6 MIT 18 gnyeeAlelYkealel 33 g++ +A+e+ +++le FUN_002331-T1 704 GDFRKAIEYHEKCLEI 719 8999*********985 PP == domain 8 score: 2.8 bits; conditional E-value: 0.3 MIT 18 gnyeeAlelYkealelLlqalk.e 40 g++e Al+ + +a+++++++ + FUN_002331-T1 744 GQFENALDKFDSAVKVFNTLRSfL 767 899**************9887754 PP >> TPR_3 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.1 3.6 2.2e+03 6 23 .. 135 152 .. 135 154 .. 0.88 2 ? 4.7 0.1 0.086 52 8 25 .. 297 314 .. 291 322 .. 0.86 3 ? 0.7 0.0 1.5 8.9e+02 7 23 .. 376 392 .. 375 394 .. 0.88 4 ? 4.9 0.0 0.07 43 7 23 .. 696 712 .. 695 714 .. 0.94 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 3.6 TPR_3 6 slAatfylkgkyqeArel 23 sl+ ++++ g++ +A e+ FUN_002331-T1 135 SLGIAYQSLGDFRKASEY 152 7899*********99765 PP == domain 2 score: 4.7 bits; conditional E-value: 0.086 TPR_3 8 AatfylkgkyqeArelya 25 + ++++ g++ +A+e+y+ FUN_002331-T1 297 GTVYQSLGDFRKAIEYYE 314 779*************95 PP == domain 3 score: 0.7 bits; conditional E-value: 1.5 TPR_3 7 lAatfylkgkyqeArel 23 l+ ++++ g++ +A+e+ FUN_002331-T1 376 LGNAYQSLGDFRKAIEY 392 7779***********97 PP == domain 4 score: 4.9 bits; conditional E-value: 0.07 TPR_3 7 lAatfylkgkyqeArel 23 l++++++ g++ +A+e+ FUN_002331-T1 696 LGYVYQSLGDFRKAIEY 712 79*************97 PP >> FbpC_C_terminal FbpC C-terminal regulatory nucleotide binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 1.6 9.5e+02 11 25 .. 73 87 .. 70 91 .. 0.91 2 ? -0.8 0.0 4.1 2.5e+03 11 25 .. 113 127 .. 110 128 .. 0.92 3 ? -1.6 0.0 7.2 4.4e+03 11 24 .. 153 166 .. 150 166 .. 0.89 4 ? 3.8 0.0 0.14 88 11 25 .. 233 247 .. 229 249 .. 0.90 5 ? -2.0 0.0 9.5 5.8e+03 11 24 .. 273 286 .. 271 287 .. 0.89 6 ? 0.4 0.0 1.7 1e+03 11 25 .. 353 367 .. 349 368 .. 0.91 7 ? 0.4 0.0 1.7 1.1e+03 11 25 .. 393 407 .. 390 409 .. 0.92 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1.6 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002331-T1 73 HEKHLEIAIEVGDRV 87 789**********98 PP == domain 2 score: -0.8 bits; conditional E-value: 4.1 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei +++G +V FUN_002331-T1 113 HEKHLEIVIEVGNRV 127 789*********998 PP == domain 3 score: -1.6 bits; conditional E-value: 7.2 FbpC_C_terminal 11 kaRhvEiSlraGqt 24 +++h Ei++++G + FUN_002331-T1 153 HKKHLEIAIEVGDR 166 899********975 PP == domain 4 score: 3.8 bits; conditional E-value: 0.14 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h EiS+++G +V FUN_002331-T1 233 HEKHLEISIEVGNRV 247 889**********98 PP == domain 5 score: -2.0 bits; conditional E-value: 9.5 FbpC_C_terminal 11 kaRhvEiSlraGqt 24 + +h Ei++++G + FUN_002331-T1 273 HEKHLEIAIEVGHR 286 789*********86 PP == domain 6 score: 0.4 bits; conditional E-value: 1.7 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002331-T1 353 HEKHLEIAIEVGDRV 367 789*********998 PP == domain 7 score: 0.4 bits; conditional E-value: 1.7 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002331-T1 393 HEKHLEIAIEVGDRV 407 789**********98 PP >> COP9_hel_rpt COP9 signalosome complex subunit 3, N-terminal helical repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.1 0.13 82 172 194 .. 297 319 .. 291 323 .. 0.86 2 ? -2.4 0.0 6.5 4e+03 172 193 .. 537 558 .. 533 562 .. 0.85 3 ? -2.9 0.0 9 5.4e+03 172 193 .. 617 638 .. 613 642 .. 0.85 4 ? 1.3 0.0 0.47 2.9e+02 172 195 .. 697 720 .. 693 726 .. 0.86 5 ? -2.8 0.0 8.8 5.3e+03 175 194 .. 740 759 .. 737 763 .. 0.82 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.13 COP9_hel_rpt 172 GmiytalknyerAlyffevavtt 194 G +y +l ++++A++++e ++ + FUN_002331-T1 297 GTVYQSLGDFRKAIEYYEKCLEI 319 89*****************9865 PP == domain 2 score: -2.4 bits; conditional E-value: 6.5 COP9_hel_rpt 172 GmiytalknyerAlyffevavt 193 G y +l ++++A+++ e ++ FUN_002331-T1 537 GNAYRSLGDFRKAIEYHEKCLE 558 67899*************9986 PP == domain 3 score: -2.9 bits; conditional E-value: 9 COP9_hel_rpt 172 GmiytalknyerAlyffevavt 193 G y +l ++++A+y +e ++ FUN_002331-T1 617 GSAYDSLGDHRKAIYSLEKCLE 638 677999************9986 PP == domain 4 score: 1.3 bits; conditional E-value: 0.47 COP9_hel_rpt 172 GmiytalknyerAlyffevavttp 195 G +y +l ++++A+++ e ++ + FUN_002331-T1 697 GYVYQSLGDFRKAIEYHEKCLEIT 720 89****************998765 PP == domain 5 score: -2.8 bits; conditional E-value: 8.8 COP9_hel_rpt 175 ytalknyerAlyffevavtt 194 y +l ++e Al f+ av + FUN_002331-T1 740 YFSLGQFENALDKFDSAVKV 759 88999999999999998865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1223 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 623 (0.0243883); expected 510.9 (0.02) Passed bias filter: 581 (0.0227442); expected 510.9 (0.02) Passed Vit filter: 75 (0.002936); expected 25.5 (0.001) Passed Fwd filter: 48 (0.00187904); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 42 [number of targets reported over threshold] # CPU time: 0.61u 0.39s 00:00:01.00 Elapsed: 00:00:00.48 # Mc/sec: 10196.70 // Query: FUN_002332-T1 [L=189] Description: FUN_002332 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-12 45.4 0.0 1.2e-11 45.0 0.0 1.1 1 Proteasome Proteasome subunit 5.7e-06 26.1 1.3 1.2e-05 25.1 1.3 1.6 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.0 0.0 9.8e-16 1.2e-11 98 189 .] 71 155 .. 57 155 .. 0.92 Alignments for each domain: == domain 1 score: 45.0 bits; conditional E-value: 9.8e-16 Proteasome 98 sgrrpfgvslliagvdeegkprLyqidpsGsvieykdavaiGsgsqaaygvlekeykedltleeavelakkalkealerdklsgknievavi 189 ++++++ ++l+++gvd +g p L ++ p+Gs+ + + + iG+ y +le+++k+d++l+ea++l+ a+ + + +d sg+ +++++i FUN_002332-T1 71 RYQGYISAALVLGGVDLNG-PTLHTVYPHGSTDKL-PLWFIGC-----YVMLESQCKPDMELDEAKKLVSVAIAAGIFNDLGSGSDVDLCII 155 56788889999*****776.***************.8*****9.....99***************************************997 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.1 1.3 9.3e-10 1.2e-05 1 18 [. 171 188 .. 171 189 .] 0.96 Alignments for each domain: == domain 1 score: 25.1 bits; conditional E-value: 9.3e-10 Pr_beta_C 1 PNergeRqgsYkfkrGTT 18 +N +g Rqg+Y +krGTT FUN_002332-T1 171 ANDKGVRQGRYSYKRGTT 188 8***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (189 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 503 (0.0196907); expected 510.9 (0.02) Passed bias filter: 461 (0.0180466); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.38s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1881.12 // Query: FUN_002333-T1 [L=1161] Description: FUN_002333 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-161 525.1 67.1 2.2e-17 63.5 0.5 11.2 13 TPR_12 Tetratricopeptide repeat 1.4e-126 402.4 33.0 1.8e-07 31.1 0.0 18.4 18 TPR_7 Tetratricopeptide repeat 3.7e-105 340.4 88.0 9.8e-08 32.0 0.7 18.6 18 TPR_1 Tetratricopeptide repeat 2.3e-79 259.9 32.4 0.00018 21.9 0.0 18.3 18 TPR_10 Tetratricopeptide repeat 1e-75 244.0 74.6 1.6e-06 28.3 0.2 18.1 17 TPR_8 Tetratricopeptide repeat 4.5e-55 179.7 71.4 3.2e-05 24.2 0.3 18.5 18 TPR_2 Tetratricopeptide repeat 5.4e-50 170.9 0.0 8.1e-50 170.4 0.0 1.2 1 CHAT CHAT domain 2e-28 96.8 36.9 1.7 9.6 0.1 17.3 16 TPR_17 Tetratricopeptide repeat 9.8e-24 81.9 31.5 1 10.7 0.0 18.3 18 TPR_14 Tetratricopeptide repeat 2e-20 73.1 23.3 0.18 12.4 0.0 14.5 15 Rapsyn_N Rapsyn N-terminal myristoylation and linker r 3.1e-18 66.6 0.1 4.9e-05 23.3 0.0 5.7 6 TPR_MalT MalT-like TPR region 3.9e-18 65.3 25.8 5.7 8.3 0.1 17.3 17 TPR_6 Tetratricopeptide repeat 3.4e-13 49.6 4.5 38 4.6 0.0 13.7 15 DUF7542 Family of unknown function (DUF7542) 1.3e-12 48.3 21.6 8.9 6.4 0.0 13.5 13 RPN7 26S proteasome subunit RPN7 1e-10 42.0 7.5 13 5.6 0.0 11.8 13 TPR_15 Tetratricopeptide repeat 1.3e-10 41.3 0.0 45 4.3 0.0 12.9 16 DBD_Tnp_Mut MuDR family transposase 1.4e-10 41.6 0.2 65 4.2 0.0 12.8 16 DUF2977 Protein of unknown function (DUF2977) 1.9e-10 41.5 31.8 0.025 15.5 0.2 12.8 14 TPR_16 Tetratricopeptide repeat 7e-10 39.1 3.3 2.3e+02 3.3 0.0 13.1 13 TPR_4 Tetratricopeptide repeat 4.1e-08 33.4 27.4 14 6.7 0.0 15.9 16 PPR PPR repeat 6e-08 33.0 0.0 8.8 6.7 0.0 9.0 11 BAG6 BCL2-associated athanogene 6 9.7e-08 32.2 0.3 4.9 6.9 0.0 6.7 6 TPR_NPHP3 Nephrocystin-3 TPR domain 1.3e-06 28.8 20.8 8.4 7.0 0.0 13.5 15 TPR_9 Tetratricopeptide repeat 7.4e-06 26.9 25.0 12 7.0 0.1 9.6 11 DUF4810 Domain of unknown function (DUF4810) 1.6e-05 25.6 20.3 0.77 10.6 0.1 9.7 10 TPR_19 Tetratricopeptide repeat 0.001 19.8 18.5 34 5.1 0.1 11.0 14 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM 0.0041 16.3 0.0 0.49 9.5 0.0 3.1 3 Transferase Transferase family 0.0054 17.5 21.4 55 4.5 0.0 10.2 12 GGDEF_2 GGDEF-like domain 0.0059 17.0 8.4 24 5.4 0.0 9.5 13 Cdc6_lid Cdc6 AAA+ ATPase-type lid domain ------ inclusion threshold ------ 0.011 16.5 0.0 52 4.6 0.0 6.3 5 NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisobut 0.015 15.6 16.9 82 3.7 0.1 9.2 8 CAMSAP_CC1 Spectrin-binding region of Ca2+-Calmodulin 0.066 13.9 16.2 18 6.1 0.0 8.5 9 TPR_3 Tetratricopeptide repeat 0.19 11.4 4.8 57 3.3 0.0 5.6 7 PSMA-like_N Maltose-forming alpha-amylase-like, N-termina 0.68 9.9 2.7 19 5.2 0.1 4.4 6 RNPP_C RNPP family C-terminal domain 1.2 9.4 8.1 3e+02 1.7 0.0 6.9 10 Urocanase_N Urocanase N-terminal domain 4 8.0 29.4 3.7 8.1 0.0 10.1 13 Mre11_C_bact Mre11 C-terminal domain, bacteria 4.2 7.8 12.9 1.5e+02 2.8 0.0 7.9 9 DUF2118 Uncharacterized protein conserved in archaea Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 8.5e-06 0.0059 21 69 .. 8 52 .. 3 52 .. 0.92 2 ! 44.6 1.1 2.5e-14 1.7e-11 8 75 .. 33 98 .. 28 100 .. 0.96 3 ! 57.8 1.0 2e-18 1.4e-15 4 75 .. 109 178 .. 106 180 .. 0.97 4 ! 54.4 1.5 2.2e-17 1.5e-14 4 75 .. 149 218 .. 147 220 .. 0.96 5 ! 57.2 0.6 3e-18 2.1e-15 4 77 .] 189 260 .. 186 260 .. 0.97 6 ! 57.9 0.4 1.7e-18 1.2e-15 4 75 .. 229 298 .. 226 300 .. 0.96 7 ! 63.5 0.5 3.1e-20 2.2e-17 5 77 .] 270 340 .. 266 340 .. 0.97 8 ! 56.6 0.1 4.5e-18 3.1e-15 4 77 .] 309 380 .. 306 380 .. 0.96 9 ! 54.4 0.8 2.2e-17 1.5e-14 5 75 .. 390 458 .. 386 460 .. 0.96 10 ! 54.7 0.5 1.8e-17 1.2e-14 5 74 .. 430 497 .. 427 500 .. 0.94 11 ! 63.3 0.2 3.6e-20 2.5e-17 5 75 .. 510 578 .. 506 580 .. 0.96 12 ! 52.5 0.1 8.6e-17 5.9e-14 5 75 .. 590 658 .. 586 660 .. 0.96 13 ! 39.0 0.0 1.4e-12 1e-09 4 75 .. 629 698 .. 626 700 .. 0.94 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 8.5e-06 TPR_12 21 eAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelle 69 +A+e++ek l + ++ +d+p+ + ++nL+ +++ lg+++eA++++e FUN_002333-T1 8 KAIECHEKHLKITMEI--GDRPG--EGYQNLAYVFQSLGNFREAIKYHE 52 8***************..99955..6********************987 PP == domain 2 score: 44.6 bits; conditional E-value: 2.5e-14 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 nlA v + lg++ eA++++e le a ++ +++ ++ a+ nLg +y+ lgd ++A+e++e+ leia FUN_002333-T1 33 NLAYVFQSLGNFREAIKYHEIHLEKAIEA--GHRVGEGSAYENLGNAYQSLGDSRKAIEYHEKRLEIA 98 9*************************999..99*********************************98 PP == domain 3 score: 57.8 bits; conditional E-value: 2e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg+ +A+e++ek le+a+++ d+ ++ a+ nLg +y+ lgd ++A+e++e+ leia FUN_002333-T1 109 NAYGNLGNAYQSLGDSRKAIEYHEKHLEIAKEV--SDRVGEGSAYENLGNAYQSLGDSRKAIEYHEKRLEIA 178 799******************************..9**********************************98 PP == domain 4 score: 54.4 bits; conditional E-value: 2.2e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg+ +A+e++ek le+a ++ +++ ++ +a+ nLg++y+ lgd ++A+e++e+ leia FUN_002333-T1 149 SAYENLGNAYQSLGDSRKAIEYHEKRLEIAIEV--GHRVGEGNAYGNLGTAYQSLGDSRKAIEYHEKHLEIA 218 6899*****************************..99*********************************98 PP == domain 5 score: 57.2 bits; conditional E-value: 3e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+ +++ lg+ +A+e++ek le+a ++ ++ ++ +a+ Lg +y+ lgd+++A+e++e+ leia++ FUN_002333-T1 189 NAYGNLGTAYQSLGDSRKAIEYHEKHLEIAIEV--RHRVGEGNAYGSLGNAYQSLGDFRKAIEYHEKILEIAKE 260 799******************************..9***********************************986 PP == domain 6 score: 57.9 bits; conditional E-value: 1.7e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+++++ lg++ +A+e++ek le+a+++ d+ ++ a+ nLg +y+ lgd+++A+e++e+ leia FUN_002333-T1 229 NAYGSLGNAYQSLGDFRKAIEYHEKILEIAKEV--SDKVGEGGAYGNLGNAYQSLGDFQKAIEYHEKHLEIA 298 78989****************************..99*********************************98 PP == domain 7 score: 63.5 bits; conditional E-value: 3.1e-20 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+++++ lg++++A+e++ek le+a ++ +++ ++ a+ nLg +y+ lgd+++A++++e+ l+ia++ FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEYHEKHLEIAIEV--GHRVGEGSAYGNLGNAYQSLGDFRKAIKYHEKHLKIAKE 340 799*****************************..99**********************************986 PP == domain 8 score: 56.6 bits; conditional E-value: 4.5e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+++++ lg++ +A++++ek l +a+++ +d+ ++ +++ Lg +y+ lgd+++A+e+ e+ leia++ FUN_002333-T1 309 SAYGNLGNAYQSLGDFRKAIKYHEKHLKIAKEV--GDRVGEGNVYGSLGSAYRSLGDFRKAIEYQEKDLEIAKE 380 7999*****************************..99******************************9999985 PP == domain 9 score: 54.4 bits; conditional E-value: 2.2e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ nl++v++ lg++ +A+e++ek l++a ++ +d+ ++ a+ nLg +y+ lgd+++A+e++ + le+a FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEYHEKNLQIAVEV--GDRAGEGGAYGNLGNAYQSLGDFRKAIEYHAKHLELA 458 799**************************999..99********************************997 PP == domain 10 score: 54.7 bits; conditional E-value: 1.8e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 a+ nl+++++ lg++ +A+e++ k lela ++ +d+ ++ a+ nLg++y+ lgd+++A+e++e+ l+i FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEYHAKHLELAIAV--GDRVGEGSAYGNLGIAYRSLGDFRKAIEYHEKDLQI 497 799*****************************..9*****************************986665 PP == domain 11 score: 63.3 bits; conditional E-value: 3.6e-20 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ nl+++++ lg++ +A+e+lek le+a ++ +d+ ++ +a+ nLg++y+ lgd+++A+e++e+ leia FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIAIEV--GDRVGEGRAYGNLGIAYRSLGDFRKAIEYHEKRLEIA 578 799*****************************..9**********************************98 PP == domain 12 score: 52.5 bits; conditional E-value: 8.6e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ nl+ v++ lg+ +A+e++ k le+a ++ +d+ ++ a+ Lg++++ lgd+++A+e++e+ l+ia FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEYHAKLLEIAIAV--GDRVGEGSAYGSLGIAFQSLGDFRKAIEYHEKGLQIA 658 799*****************************..9*********************************998 PP == domain 13 score: 39.0 bits; conditional E-value: 1.4e-12 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+ + + lg++ +A+e++ek l++a ++ +d+ ++ ++++n+g y+ lg++e Al+ + a++++ FUN_002333-T1 629 SAYGSLGIAFQSLGDFRKAIEYHEKGLQIAIEV--GDRAGEGESHHNIGLGYSSLGQFENALDKFDSAVKVF 698 68888****************************..99****************************9998875 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.058 40 12 35 .. 3 26 .. 1 27 [. 0.88 2 ! 17.6 0.0 5.7e-06 0.0039 3 35 .. 32 64 .. 31 65 .. 0.89 3 ! 24.1 0.1 5e-08 3.5e-05 1 35 [. 70 104 .. 70 105 .. 0.93 4 ! 29.8 0.0 7.2e-10 5e-07 1 35 [. 110 144 .. 110 145 .. 0.96 5 ! 24.1 0.1 5e-08 3.5e-05 1 35 [. 150 184 .. 150 185 .. 0.93 6 ! 23.6 0.1 7e-08 4.8e-05 1 35 [. 190 224 .. 190 225 .. 0.92 7 ! 26.7 0.0 6.9e-09 4.8e-06 1 35 [. 230 264 .. 230 265 .. 0.94 8 ! 30.1 0.0 5.7e-10 3.9e-07 1 35 [. 270 304 .. 270 305 .. 0.94 9 ! 31.1 0.0 2.7e-10 1.8e-07 1 35 [. 310 344 .. 310 345 .. 0.96 10 ! 21.5 0.0 3.4e-07 0.00023 3 35 .. 352 384 .. 350 385 .. 0.94 11 ! 26.0 0.0 1.2e-08 8.5e-06 1 36 [] 390 425 .. 390 425 .. 0.95 12 ! 27.5 0.1 3.9e-09 2.7e-06 1 35 [. 430 464 .. 430 465 .. 0.95 13 ! 27.0 0.1 5.7e-09 4e-06 1 36 [] 470 505 .. 470 505 .. 0.95 14 ! 23.2 0.0 9.2e-08 6.4e-05 1 35 [. 510 544 .. 510 545 .. 0.93 15 ! 27.3 0.0 4.6e-09 3.2e-06 1 35 [. 550 584 .. 550 585 .. 0.95 16 ! 18.2 0.0 3.8e-06 0.0027 1 35 [. 590 624 .. 590 625 .. 0.94 17 ! 17.8 0.0 5e-06 0.0034 1 35 [. 630 664 .. 630 665 .. 0.93 18 ! 8.2 0.0 0.0061 4.2 1 24 [. 670 693 .. 670 697 .. 0.90 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.058 TPR_7 12 lGdydeAirlyerlLalakdpedr 35 +G ++Ai+++e++L ++++ +dr FUN_002333-T1 3 SGYLRKAIECHEKHLKITMEIGDR 26 68889*************999887 PP == domain 2 score: 17.6 bits; conditional E-value: 5.7e-06 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La ++++lG+++eAi+++e +L+ a + ++r FUN_002333-T1 32 QNLAYVFQSLGNFREAIKYHEIHLEKAIEAGHR 64 69**********************988777665 PP == domain 3 score: 24.1 bits; conditional E-value: 5e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+++y++lGd ++Ai+++e+ L++a + ++r FUN_002333-T1 70 AYENLGNAYQSLGDSRKAIEYHEKRLEIAIEVGHR 104 789*************************9888876 PP == domain 4 score: 29.8 bits; conditional E-value: 7.2e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd ++Ai+++e++L++ak+ +dr FUN_002333-T1 110 AYGNLGNAYQSLGDSRKAIEYHEKHLEIAKEVSDR 144 789****************************9998 PP == domain 5 score: 24.1 bits; conditional E-value: 5e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+++y++lGd ++Ai+++e+ L++a + ++r FUN_002333-T1 150 AYENLGNAYQSLGDSRKAIEYHEKRLEIAIEVGHR 184 789*************************9888876 PP == domain 6 score: 23.6 bits; conditional E-value: 7e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd ++Ai+++e++L++a + ++r FUN_002333-T1 190 AYGNLGTAYQSLGDSRKAIEYHEKHLEIAIEVRHR 224 789*************************9887766 PP == domain 7 score: 26.7 bits; conditional E-value: 6.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L++ak+ +d+ FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKILEIAKEVSDK 264 7899**************************99986 PP == domain 8 score: 30.1 bits; conditional E-value: 5.7e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEYHEKHLEIAIEVGHR 304 789*************************9988876 PP == domain 9 score: 31.1 bits; conditional E-value: 2.7e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L +ak+ +dr FUN_002333-T1 310 AYGNLGNAYQSLGDFRKAIKYHEKHLKIAKEVGDR 344 789*****************************998 PP == domain 10 score: 21.5 bits; conditional E-value: 3.4e-07 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 ++L+++yr+lGd+++Ai++ e+ L++ak+ +dr FUN_002333-T1 352 GSLGSAYRSLGDFRKAIEYQEKDLEIAKEVSDR 384 78***************************9998 PP == domain 11 score: 26.0 bits; conditional E-value: 1.2e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+++y++lGd+++Ai+++e+ L++a + +dr+ FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEYHEKNLQIAVEVGDRA 425 789***************************999985 PP == domain 12 score: 27.5 bits; conditional E-value: 3.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L+la +dr FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEYHAKHLELAIAVGDR 464 789**************************999987 PP == domain 13 score: 27.0 bits; conditional E-value: 5.7e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+ +yr+lGd+++Ai+++e+ L++a + +dr+ FUN_002333-T1 470 AYGNLGIAYRSLGDFRKAIEYHEKDLQIAIEVGDRA 505 789**************************9999985 PP == domain 14 score: 23.2 bits; conditional E-value: 9.2e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L++a + +dr FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIAIEVGDR 544 789*********************99999988887 PP == domain 15 score: 27.3 bits; conditional E-value: 4.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +yr+lGd+++Ai+++e+ L++a + +dr FUN_002333-T1 550 AYGNLGIAYRSLGDFRKAIEYHEKRLEIAIEVGDR 584 789**************************999997 PP == domain 16 score: 18.2 bits; conditional E-value: 3.8e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y +lGd ++Ai+++ +lL++a +dr FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEYHAKLLEIAIAVGDR 624 789**************************999887 PP == domain 17 score: 17.8 bits; conditional E-value: 5e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ ++++lGd+++Ai+++e+ L++a + +dr FUN_002333-T1 630 AYGSLGIAFQSLGDFRKAIEYHEKGLQIAIEVGDR 664 7899********************99999999988 PP == domain 18 score: 8.2 bits; conditional E-value: 0.0061 TPR_7 1 aLsaLariyrklGdydeAirlyer 24 ++++++ y++lG++++A++ ++ FUN_002333-T1 670 SHHNIGLGYSSLGQFENALDKFDS 693 589*****************9987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.1 0.82 5.7e+02 18 30 .. 7 19 .. 6 19 .. 0.88 2 ! 14.2 0.3 5.8e-05 0.04 2 25 .. 29 52 .. 28 58 .. 0.89 3 ! 19.8 0.3 1e-06 0.0007 3 26 .. 70 93 .. 68 98 .. 0.90 4 ! 27.5 0.5 3.7e-09 2.6e-06 2 31 .. 109 138 .. 108 140 .. 0.94 5 ! 19.8 0.3 1e-06 0.0007 3 26 .. 150 173 .. 148 178 .. 0.90 6 ! 24.5 0.2 3.3e-08 2.3e-05 2 30 .. 189 217 .. 188 218 .. 0.95 7 ! 28.7 0.3 1.6e-09 1.1e-06 2 31 .. 229 258 .. 228 260 .. 0.94 8 ! 31.3 0.7 2.4e-10 1.6e-07 3 30 .. 270 297 .. 269 298 .. 0.96 9 ! 29.9 0.5 6.7e-10 4.7e-07 3 31 .. 310 338 .. 308 340 .. 0.94 10 ! 15.3 0.0 2.7e-05 0.019 3 23 .. 350 370 .. 348 373 .. 0.94 11 ! 27.5 0.3 3.8e-09 2.6e-06 3 30 .. 390 417 .. 389 418 .. 0.96 12 ! 25.8 1.0 1.3e-08 9e-06 3 30 .. 430 457 .. 429 458 .. 0.95 13 ! 23.5 0.1 7e-08 4.8e-05 3 26 .. 470 493 .. 468 497 .. 0.94 14 ! 32.0 0.7 1.4e-10 9.8e-08 3 30 .. 510 537 .. 509 538 .. 0.97 15 ! 24.7 0.2 2.8e-08 1.9e-05 2 26 .. 549 573 .. 548 578 .. 0.91 16 ! 13.7 0.8 8.4e-05 0.058 2 30 .. 589 617 .. 588 618 .. 0.91 17 ! 22.5 0.0 1.5e-07 0.0001 3 30 .. 630 657 .. 628 658 .. 0.95 18 ! 12.6 0.0 0.00019 0.13 2 30 .. 669 697 .. 668 700 .. 0.91 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.82 TPR_1 18 deAleyyekALel 30 +A+e+ ek L++ FUN_002333-T1 7 RKAIECHEKHLKI 19 59*******9987 PP == domain 2 score: 14.2 bits; conditional E-value: 5.8e-05 TPR_1 2 kalynlGnayfklgkydeAleyye 25 + + nl++++++lg++ eA++y e FUN_002333-T1 29 EGYQNLAYVFQSLGNFREAIKYHE 52 5799*****************976 PP == domain 3 score: 19.8 bits; conditional E-value: 1e-06 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ nlGnay++lg+ +A+ey ek FUN_002333-T1 70 AYENLGNAYQSLGDSRKAIEYHEK 93 899******************998 PP == domain 4 score: 27.5 bits; conditional E-value: 3.7e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGnay++lg+ +A+ey ek Le+ FUN_002333-T1 109 NAYGNLGNAYQSLGDSRKAIEYHEKHLEIA 138 69**************************96 PP == domain 5 score: 19.8 bits; conditional E-value: 1e-06 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ nlGnay++lg+ +A+ey ek FUN_002333-T1 150 AYENLGNAYQSLGDSRKAIEYHEK 173 899******************998 PP == domain 6 score: 24.5 bits; conditional E-value: 3.3e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay++lg+ +A+ey ek Le+ FUN_002333-T1 189 NAYGNLGTAYQSLGDSRKAIEYHEKHLEI 217 69*************************98 PP == domain 7 score: 28.7 bits; conditional E-value: 1.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002333-T1 229 NAYGSLGNAYQSLGDFRKAIEYHEKILEIA 258 59**************************96 PP == domain 8 score: 31.3 bits; conditional E-value: 2.4e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++++A+ey ek Le+ FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEYHEKHLEI 297 8*************************98 PP == domain 9 score: 29.9 bits; conditional E-value: 6.7e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A++y ek L++ FUN_002333-T1 310 AYGNLGNAYQSLGDFRKAIKYHEKHLKIA 338 9*************************996 PP == domain 10 score: 15.3 bits; conditional E-value: 2.7e-05 TPR_1 3 alynlGnayfklgkydeAley 23 ++ lG ay++lg++ +A+ey FUN_002333-T1 350 VYGSLGSAYRSLGDFRKAIEY 370 7999****************8 PP == domain 11 score: 27.5 bits; conditional E-value: 3.8e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGn+y++lg++ +A+ey ek L++ FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEYHEKNLQI 417 8***********************9998 PP == domain 12 score: 25.8 bits; conditional E-value: 1.3e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A+ey k Lel FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEYHAKHLEL 457 8*********************999998 PP == domain 13 score: 23.5 bits; conditional E-value: 7e-08 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ nlG ay++lg++ +A+ey ek FUN_002333-T1 470 AYGNLGIAYRSLGDFRKAIEYHEK 493 9********************987 PP == domain 14 score: 32.0 bits; conditional E-value: 1.4e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEI 537 8**************************8 PP == domain 15 score: 24.7 bits; conditional E-value: 2.8e-08 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ nlG ay++lg++ +A+ey ek FUN_002333-T1 549 RAYGNLGIAYRSLGDFRKAIEYHEK 573 79********************998 PP == domain 16 score: 13.7 bits; conditional E-value: 8.4e-05 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG +y++lg+ +A+ey k Le+ FUN_002333-T1 589 YAYGNLGIVYLSLGDCRKAIEYHAKLLEI 617 69********************9888876 PP == domain 17 score: 22.5 bits; conditional E-value: 1.5e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lG a+++lg++ +A+ey ek L++ FUN_002333-T1 630 AYGSLGIAFQSLGDFRKAIEYHEKGLQI 657 89************************98 PP == domain 18 score: 12.6 bits; conditional E-value: 0.00019 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +++ n+G+ y +lg+++ Al+ ++ A+++ FUN_002333-T1 669 ESHHNIGLGYSSLGQFENALDKFDSAVKV 697 5799*****************99999875 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.76 5.2e+02 24 36 .. 5 17 .. 3 19 .. 0.91 2 ! 8.9 0.1 0.0032 2.2 5 26 .. 31 52 .. 30 52 .. 0.94 3 ! 13.5 0.1 0.00011 0.079 3 34 .. 69 100 .. 68 101 .. 0.91 4 ! 16.3 0.1 1.4e-05 0.0099 4 35 .. 110 141 .. 108 144 .. 0.94 5 ! 13.5 0.1 0.00011 0.079 3 34 .. 149 180 .. 148 181 .. 0.91 6 ! 12.4 0.0 0.00025 0.17 4 34 .. 190 220 .. 188 221 .. 0.91 7 ! 20.8 0.0 5.5e-07 0.00038 4 35 .. 230 261 .. 228 264 .. 0.94 8 ! 19.3 0.0 1.6e-06 0.0011 4 35 .. 270 301 .. 269 301 .. 0.92 9 ! 19.4 0.0 1.6e-06 0.0011 3 35 .. 309 341 .. 308 341 .. 0.95 10 ! 18.0 0.0 4.2e-06 0.0029 5 35 .. 351 381 .. 349 384 .. 0.94 11 ! 20.2 0.0 8.9e-07 0.00061 4 35 .. 390 421 .. 389 421 .. 0.94 12 ! 14.1 0.1 7.2e-05 0.05 4 31 .. 430 457 .. 429 461 .. 0.87 13 ! 20.6 0.0 6.6e-07 0.00046 3 35 .. 469 501 .. 468 501 .. 0.94 14 ! 21.9 0.0 2.6e-07 0.00018 4 35 .. 510 541 .. 509 541 .. 0.94 15 ! 16.4 0.0 1.4e-05 0.0098 4 34 .. 550 580 .. 548 581 .. 0.90 16 ! 12.0 0.1 0.00034 0.24 4 33 .. 590 619 .. 589 621 .. 0.92 17 ! 13.0 0.0 0.00016 0.11 3 35 .. 629 661 .. 628 661 .. 0.94 18 ? 1.8 0.0 0.52 3.6e+02 6 23 .. 672 689 .. 670 697 .. 0.85 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.76 TPR_10 24 lleealairervl 36 +l++a++++e++l FUN_002333-T1 5 YLRKAIECHEKHL 17 89*********98 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0032 TPR_10 5 lnnLanalraqgryeeAeelle 26 + nLa + +++g++ eA +++e FUN_002333-T1 31 YQNLAYVFQSLGNFREAIKYHE 52 67*****************987 PP == domain 3 score: 13.5 bits; conditional E-value: 0.00011 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+na++++g+ A e++e+ l+i+ + FUN_002333-T1 69 SAYENLGNAYQSLGDSRKAIEYHEKRLEIAIE 100 799*********************98888766 PP == domain 4 score: 16.3 bits; conditional E-value: 1.4e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++g+ A e++e+ l+i+++v FUN_002333-T1 110 AYGNLGNAYQSLGDSRKAIEYHEKHLEIAKEV 141 89***************************998 PP == domain 5 score: 13.5 bits; conditional E-value: 0.00011 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+na++++g+ A e++e+ l+i+ + FUN_002333-T1 149 SAYENLGNAYQSLGDSRKAIEYHEKRLEIAIE 180 799*********************98888766 PP == domain 6 score: 12.4 bits; conditional E-value: 0.00025 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL++a++++g+ A e++e+ l+i+ + FUN_002333-T1 190 AYGNLGTAYQSLGDSRKAIEYHEKHLEIAIE 220 89**********************9999876 PP == domain 7 score: 20.8 bits; conditional E-value: 5.5e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+++v FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKILEIAKEV 261 7999**************************98 PP == domain 8 score: 19.3 bits; conditional E-value: 1.6e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++g+++ A e++e+ l+i+ +v FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEYHEKHLEIAIEV 301 799*********************99998765 PP == domain 9 score: 19.4 bits; conditional E-value: 1.6e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A +++e+ l+i+++v FUN_002333-T1 309 SAYGNLGNAYQSLGDFRKAIKYHEKHLKIAKEV 341 79***********************99999986 PP == domain 10 score: 18.0 bits; conditional E-value: 4.2e-06 TPR_10 5 lnnLanalraqgryeeAeelleealairerv 35 + L+ a+r++g++ A e++e+ l+i+++v FUN_002333-T1 351 YGSLGSAYRSLGDFRKAIEYQEKDLEIAKEV 381 789**************************98 PP == domain 11 score: 20.2 bits; conditional E-value: 8.9e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+n+++++g++ A e++e+ l+i+ +v FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEYHEKNLQIAVEV 421 799************************98775 PP == domain 12 score: 14.1 bits; conditional E-value: 7.2e-05 TPR_10 4 slnnLanalraqgryeeAeelleealai 31 ++ nL+na++++g++ A e++ + l++ FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEYHAKHLEL 457 799******************9886665 PP == domain 13 score: 20.6 bits; conditional E-value: 6.6e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+ a+r++g++ A e++e+ l+i+ +v FUN_002333-T1 469 SAYGNLGIAYRSLGDFRKAIEYHEKDLQIAIEV 501 79**************************98876 PP == domain 14 score: 21.9 bits; conditional E-value: 2.6e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++g++ A e+le+ l+i+ +v FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIAIEV 541 799*************************9876 PP == domain 15 score: 16.4 bits; conditional E-value: 1.4e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+ a+r++g++ A e++e+ l+i+ + FUN_002333-T1 550 AYGNLGIAYRSLGDFRKAIEYHEKRLEIAIE 580 89*********************98888766 PP == domain 16 score: 12.0 bits; conditional E-value: 0.00034 TPR_10 4 slnnLanalraqgryeeAeelleealaire 33 ++ nL+ ++ ++g+ A e++ + l+i+ FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEYHAKLLEIAI 619 799***********************9976 PP == domain 17 score: 13.0 bits; conditional E-value: 0.00016 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+ a +++g++ A e++e+ l+i+ +v FUN_002333-T1 629 SAYGSLGIAFQSLGDFRKAIEYHEKGLQIAIEV 661 6899*************************9876 PP == domain 18 score: 1.8 bits; conditional E-value: 0.52 TPR_10 6 nnLanalraqgryeeAee 23 +n++ ++++g++e A++ FUN_002333-T1 672 HNIGLGYSSLGQFENALD 689 799999*******99986 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.2 0.1 0.0007 0.48 2 23 .. 29 50 .. 28 61 .. 0.91 2 ! 16.9 0.3 1e-05 0.0072 2 30 .. 69 97 .. 68 98 .. 0.88 3 ! 19.3 0.3 1.7e-06 0.0012 3 32 .. 110 139 .. 108 140 .. 0.91 4 ! 16.9 0.3 1e-05 0.0072 2 30 .. 149 177 .. 148 178 .. 0.88 5 ! 16.9 0.2 1e-05 0.0072 3 30 .. 190 217 .. 188 218 .. 0.90 6 ! 21.6 0.1 3.3e-07 0.00023 3 32 .. 230 259 .. 228 261 .. 0.94 7 ! 20.7 0.2 6.3e-07 0.00043 3 30 .. 270 297 .. 268 298 .. 0.91 8 ! 19.9 0.3 1.2e-06 0.00081 2 31 .. 309 338 .. 308 340 .. 0.91 9 ! 20.5 0.1 7.6e-07 0.00052 3 31 .. 350 378 .. 348 380 .. 0.90 10 ! 17.8 0.1 5.2e-06 0.0036 3 26 .. 390 413 .. 388 418 .. 0.89 11 ! 17.3 0.3 7.6e-06 0.0052 3 23 .. 430 450 .. 428 458 .. 0.89 12 ! 15.6 0.1 2.8e-05 0.019 2 26 .. 469 493 .. 468 498 .. 0.91 13 ! 28.3 0.2 2.3e-09 1.6e-06 3 31 .. 510 538 .. 508 538 .. 0.95 14 ! 17.5 0.1 6.6e-06 0.0046 2 30 .. 549 577 .. 548 578 .. 0.89 15 ! 10.4 0.4 0.0012 0.84 3 30 .. 590 617 .. 588 618 .. 0.93 16 ! 12.1 0.0 0.00036 0.25 2 30 .. 629 657 .. 628 658 .. 0.93 17 ? 6.3 0.0 0.026 18 2 22 .. 669 689 .. 668 698 .. 0.84 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.0007 TPR_8 2 eayynlGliylklgdyeeAkey 23 e y+nl+++ ++lg++ eA++y FUN_002333-T1 29 EGYQNLAYVFQSLGNFREAIKY 50 569*****************99 PP == domain 2 score: 16.9 bits; conditional E-value: 1e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd +A+ey ek le+ FUN_002333-T1 69 SAYENLGNAYQSLGDSRKAIEYHEKRLEI 97 58********************8886665 PP == domain 3 score: 19.3 bits; conditional E-value: 1.7e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG++y++lgd +A+ey ek le+++ FUN_002333-T1 110 AYGNLGNAYQSLGDSRKAIEYHEKHLEIAK 139 9********************999998875 PP == domain 4 score: 16.9 bits; conditional E-value: 1e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd +A+ey ek le+ FUN_002333-T1 149 SAYENLGNAYQSLGDSRKAIEYHEKRLEI 177 58********************8886665 PP == domain 5 score: 16.9 bits; conditional E-value: 1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG +y++lgd +A+ey ek le+ FUN_002333-T1 190 AYGNLGTAYQSLGDSRKAIEYHEKHLEI 217 9********************9987776 PP == domain 6 score: 21.6 bits; conditional E-value: 3.3e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKILEIAK 259 89*************************986 PP == domain 7 score: 20.7 bits; conditional E-value: 6.3e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+++A+ey ek le+ FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEYHEKHLEI 297 8********************9987776 PP == domain 8 score: 19.9 bits; conditional E-value: 1.2e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay nlG++y++lgd+ +A++y ek l+++ FUN_002333-T1 309 SAYGNLGNAYQSLGDFRKAIKYHEKHLKIA 338 59********************99988886 PP == domain 9 score: 20.5 bits; conditional E-value: 7.6e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 +y lG++y++lgd+ +A+ey ek le++ FUN_002333-T1 350 VYGSLGSAYRSLGDFRKAIEYQEKDLEIA 378 7999*******************977776 PP == domain 10 score: 17.8 bits; conditional E-value: 5.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 ay nlG++y++lgd+ +A+ey ek FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEYHEK 413 8********************776 PP == domain 11 score: 17.3 bits; conditional E-value: 7.6e-06 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay nlG++y++lgd+ +A+ey FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEY 450 8*******************9 PP == domain 12 score: 15.6 bits; conditional E-value: 2.8e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay nlG +y++lgd+ +A+ey ek FUN_002333-T1 469 SAYGNLGIAYRSLGDFRKAIEYHEK 493 59*******************9665 PP == domain 13 score: 28.3 bits; conditional E-value: 2.3e-09 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay nlG++y++lgd+ +A+ey+ek le++ FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIA 538 8*************************995 PP == domain 14 score: 17.5 bits; conditional E-value: 6.6e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG +y++lgd+ +A+ey ek le+ FUN_002333-T1 549 RAYGNLGIAYRSLGDFRKAIEYHEKRLEI 577 89********************8886665 PP == domain 15 score: 10.4 bits; conditional E-value: 0.0012 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG +yl+lgd +A+ey k le+ FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEYHAKLLEI 617 8********************9999998 PP == domain 16 score: 12.1 bits; conditional E-value: 0.00036 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG + ++lgd+ +A+ey ek l++ FUN_002333-T1 629 SAYGSLGIAFQSLGDFRKAIEYHEKGLQI 657 5899********************99987 PP == domain 17 score: 6.3 bits; conditional E-value: 0.026 TPR_8 2 eayynlGliylklgdyeeAke 22 e+++n+Gl y++lg++e+A FUN_002333-T1 669 ESHHNIGLGYSSLGQFENALD 689 6899**************975 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.9 0.1 0.0037 2.6 2 23 .. 29 50 .. 28 50 .. 0.94 2 ! 11.0 0.2 0.00079 0.55 3 23 .. 70 90 .. 68 96 .. 0.94 3 ! 11.0 0.3 0.00081 0.56 3 23 .. 110 130 .. 108 140 .. 0.89 4 ! 11.0 0.2 0.00079 0.55 3 23 .. 150 170 .. 148 176 .. 0.94 5 ! 8.3 0.1 0.0056 3.9 3 23 .. 190 210 .. 188 217 .. 0.93 6 ! 16.0 0.1 2e-05 0.014 3 32 .. 230 259 .. 228 261 .. 0.90 7 ! 16.1 0.3 1.9e-05 0.013 3 23 .. 270 290 .. 268 298 .. 0.92 8 ! 14.5 0.2 6e-05 0.041 3 23 .. 310 330 .. 308 340 .. 0.89 9 ! 14.6 0.1 5.7e-05 0.04 4 31 .. 351 378 .. 348 380 .. 0.89 10 ! 13.3 0.1 0.00014 0.096 3 23 .. 390 410 .. 388 413 .. 0.94 11 ! 13.9 0.3 9.6e-05 0.066 3 23 .. 430 450 .. 428 450 .. 0.94 12 ! 14.6 0.1 5.5e-05 0.038 3 26 .. 470 493 .. 468 499 .. 0.86 13 ! 24.2 0.3 4.7e-08 3.2e-05 3 31 .. 510 538 .. 508 540 .. 0.94 14 ! 14.1 0.3 8.1e-05 0.056 2 23 .. 549 570 .. 548 576 .. 0.94 15 ? 6.5 0.4 0.022 15 2 30 .. 589 617 .. 588 618 .. 0.87 16 ! 9.7 0.0 0.0021 1.4 3 30 .. 630 657 .. 628 660 .. 0.89 17 ! 12.2 0.0 0.00032 0.22 2 30 .. 669 697 .. 668 700 .. 0.92 18 ? -0.5 0.0 3.7 2.6e+03 10 26 .. 729 745 .. 728 748 .. 0.84 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0037 TPR_2 2 ealynlGlayyklgdyeeAlea 23 e++ nl+++ lg++ eA+++ FUN_002333-T1 29 EGYQNLAYVFQSLGNFREAIKY 50 7899****************98 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00079 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd +A+e+ FUN_002333-T1 70 AYENLGNAYQSLGDSRKAIEY 90 899****************98 PP == domain 3 score: 11.0 bits; conditional E-value: 0.00081 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd +A+e+ FUN_002333-T1 110 AYGNLGNAYQSLGDSRKAIEY 130 899*****************8 PP == domain 4 score: 11.0 bits; conditional E-value: 0.00079 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd +A+e+ FUN_002333-T1 150 AYENLGNAYQSLGDSRKAIEY 170 899****************98 PP == domain 5 score: 8.3 bits; conditional E-value: 0.0056 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd +A+e+ FUN_002333-T1 190 AYGNLGTAYQSLGDSRKAIEY 210 899****************98 PP == domain 6 score: 16.0 bits; conditional E-value: 2e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a+ lG+ay lgd+ +A+e+ ek le++ FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKILEIAK 259 7888*****************999999976 PP == domain 7 score: 16.1 bits; conditional E-value: 1.9e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+++A+e+ FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEY 290 799****************98 PP == domain 8 score: 14.5 bits; conditional E-value: 6e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+++ FUN_002333-T1 310 AYGNLGNAYQSLGDFRKAIKY 330 899****************98 PP == domain 9 score: 14.6 bits; conditional E-value: 5.7e-05 TPR_2 4 lynlGlayyklgdyeeAleayekAleld 31 + lG ay+ lgd+ +A+e+ ek le++ FUN_002333-T1 351 YGSLGSAYRSLGDFRKAIEYQEKDLEIA 378 6679*******************99987 PP == domain 10 score: 13.3 bits; conditional E-value: 0.00014 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG++y lgd+ +A+e+ FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEY 410 799****************98 PP == domain 11 score: 13.9 bits; conditional E-value: 9.6e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEY 450 799****************98 PP == domain 12 score: 14.6 bits; conditional E-value: 5.5e-05 TPR_2 3 alynlGlayyklgdyeeAleayek 26 a+ nlG ay+ lgd+ +A+e+ ek FUN_002333-T1 470 AYGNLGIAYRSLGDFRKAIEYHEK 493 899*****************9666 PP == domain 13 score: 24.2 bits; conditional E-value: 4.7e-08 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG+ay lgd+ +A+e++ek le++ FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIA 538 799***********************986 PP == domain 14 score: 14.1 bits; conditional E-value: 8.1e-05 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ nlG ay+ lgd+ +A+e+ FUN_002333-T1 549 RAYGNLGIAYRSLGDFRKAIEY 570 6899****************98 PP == domain 15 score: 6.5 bits; conditional E-value: 0.022 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ nlG +y+ lgd +A+e+ k le+ FUN_002333-T1 589 YAYGNLGIVYLSLGDCRKAIEYHAKLLEI 617 6899*****************97777765 PP == domain 16 score: 9.7 bits; conditional E-value: 0.0021 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a+ lG a lgd+ +A+e+ ek l++ FUN_002333-T1 630 AYGSLGIAFQSLGDFRKAIEYHEKGLQI 657 67789****************9999987 PP == domain 17 score: 12.2 bits; conditional E-value: 0.00032 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 e ++n Gl y lg++e Al+ ++ A++ FUN_002333-T1 669 ESHHNIGLGYSSLGQFENALDKFDSAVKV 697 789*********************99985 PP == domain 18 score: -0.5 bits; conditional E-value: 3.7 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002333-T1 729 SLLRIGKIDEALFAADQ 745 67899*******98776 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.4 0.0 1.2e-52 8.1e-50 8 291 .] 885 1147 .. 880 1147 .. 0.89 Alignments for each domain: == domain 1 score: 170.4 bits; conditional E-value: 1.2e-52 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ + viv dgaL +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ ++ k FUN_002333-T1 885 YDAVIGPIEDLL-GPEDDEMVIVSDGALCFIPWAAVIESIR---------IRIVPSLKSyqlISSVPEGYHKKTGA--LLVGNPCTKQ----LK 962 8999***99997.77777*****************988863.........55556654422266666666666666..*******885....47 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 +++lp +++E++++a++l+ +l+g++at+ ++++ + ++++++H+a+Hg + ++L++ n + ed L++++++ FUN_002333-T1 963 KPLEPLPFAQKEVEMIAAILKN---TPLVGKQATKAEVMKRM-SSVGLIHIAAHGNEV-----TGQIALSP-NPGwtqfpkeEDYILKMSDVQA 1046 777*****************77...8***************9.************988.....88899974.4445889998************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at+++mk+fy++l+ gk++++A++q + l+++++ +++ FUN_002333-T1 1047 ANLR-ARLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATKEFMKRFYQHLKEGKTASAAVHQSMKYLRESEE----FSE 1135 ****.*****************************************************************************99997....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002333-T1 1136 MWYWAPFQLIGD 1147 ***********7 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 0.096 66 14 33 .. 29 48 .. 27 49 .. 0.91 2 ! 8.9 0.0 0.0042 2.9 14 34 .] 69 89 .. 66 89 .. 0.92 3 ! 9.6 0.1 0.0025 1.7 14 34 .] 109 129 .. 107 129 .. 0.93 4 ! 8.8 0.1 0.0044 3.1 14 34 .] 149 169 .. 147 169 .. 0.92 5 ! 8.7 0.1 0.0049 3.4 14 34 .] 189 209 .. 187 209 .. 0.93 6 ? 5.6 0.1 0.048 33 14 34 .] 229 249 .. 227 249 .. 0.92 7 ! 8.9 0.1 0.004 2.8 15 34 .] 270 289 .. 268 289 .. 0.93 8 ! 7.7 0.1 0.01 6.9 14 33 .. 309 328 .. 307 329 .. 0.92 9 ? 2.3 0.0 0.52 3.6e+02 14 34 .] 349 369 .. 347 369 .. 0.90 10 ? 7.2 0.0 0.014 9.6 15 34 .] 390 409 .. 388 409 .. 0.93 11 ? 7.5 0.1 0.011 7.9 15 34 .] 430 449 .. 427 449 .. 0.93 12 ? 7.1 0.0 0.015 10 14 34 .] 469 489 .. 467 489 .. 0.92 13 ? 7.5 0.1 0.011 7.9 15 34 .] 510 529 .. 507 529 .. 0.93 14 ? 7.1 0.0 0.015 10 15 34 .] 550 569 .. 547 569 .. 0.92 15 ? 3.8 0.0 0.17 1.2e+02 14 32 .. 589 607 .. 587 609 .. 0.83 16 ? 0.4 0.0 2.1 1.5e+03 15 34 .] 630 649 .. 628 649 .. 0.91 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.096 TPR_17 14 dayynLArlllnnGqleeAl 33 + y+nLA++ + +G++ eA+ FUN_002333-T1 29 EGYQNLAYVFQSLGNFREAI 48 679***************98 PP == domain 2 score: 8.9 bits; conditional E-value: 0.0042 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 69 SAYENLGNAYQSLGDSRKAIE 89 59*****************85 PP == domain 3 score: 9.6 bits; conditional E-value: 0.0025 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002333-T1 109 NAYGNLGNAYQSLGDSRKAIE 129 79*****************85 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0044 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 149 SAYENLGNAYQSLGDSRKAIE 169 59*****************85 PP == domain 5 score: 8.7 bits; conditional E-value: 0.0049 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002333-T1 189 NAYGNLGTAYQSLGDSRKAIE 209 79*****************85 PP == domain 6 score: 5.6 bits; conditional E-value: 0.048 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002333-T1 229 NAYGSLGNAYQSLGDFRKAIE 249 79****************985 PP == domain 7 score: 8.9 bits; conditional E-value: 0.004 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++++A++ FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIE 289 89****************85 PP == domain 8 score: 7.7 bits; conditional E-value: 0.01 TPR_17 14 dayynLArlllnnGqleeAl 33 ay nL+++++ +G++ +A+ FUN_002333-T1 309 SAYGNLGNAYQSLGDFRKAI 328 59***************998 PP == domain 9 score: 2.3 bits; conditional E-value: 0.52 TPR_17 14 dayynLArlllnnGqleeAlq 34 ++y L+ +++ +G++ +A++ FUN_002333-T1 349 NVYGSLGSAYRSLGDFRKAIE 369 57999*************985 PP == domain 10 score: 7.2 bits; conditional E-value: 0.014 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIE 409 89***************985 PP == domain 11 score: 7.5 bits; conditional E-value: 0.011 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIE 449 8****************985 PP == domain 12 score: 7.1 bits; conditional E-value: 0.015 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 469 SAYGNLGIAYRSLGDFRKAIE 489 59****************985 PP == domain 13 score: 7.5 bits; conditional E-value: 0.011 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIE 529 8****************985 PP == domain 14 score: 7.1 bits; conditional E-value: 0.015 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002333-T1 550 AYGNLGIAYRSLGDFRKAIE 569 9****************985 PP == domain 15 score: 3.8 bits; conditional E-value: 0.17 TPR_17 14 dayynLArlllnnGqleeA 32 +ay nL++++l +G+ +A FUN_002333-T1 589 YAYGNLGIVYLSLGDCRKA 607 69***********985555 PP == domain 16 score: 0.4 bits; conditional E-value: 2.1 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++ + +G++ +A++ FUN_002333-T1 630 AYGSLGIAFQSLGDFRKAIE 649 8999************9985 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.29 2e+02 3 28 .. 30 55 .. 28 60 .. 0.85 2 ? 4.6 0.1 0.15 1e+02 3 29 .. 70 96 .. 69 98 .. 0.88 3 ? 4.1 0.0 0.21 1.4e+02 6 31 .. 113 138 .. 109 143 .. 0.85 4 ? 4.6 0.1 0.15 1e+02 3 29 .. 150 176 .. 149 178 .. 0.88 5 ? 2.0 0.0 0.98 6.8e+02 6 29 .. 193 216 .. 189 218 .. 0.86 6 ! 8.5 0.0 0.008 5.5 5 31 .. 232 258 .. 229 263 .. 0.87 7 ? 6.3 0.0 0.042 29 6 29 .. 273 296 .. 269 298 .. 0.87 8 ? 6.4 0.0 0.038 26 6 31 .. 313 338 .. 309 343 .. 0.87 9 ? 3.2 0.0 0.4 2.8e+02 6 23 .. 353 370 .. 349 370 .. 0.88 10 ? 2.5 0.0 0.71 4.9e+02 7 25 .. 394 412 .. 389 413 .. 0.86 11 ? 4.5 0.1 0.16 1.1e+02 6 29 .. 433 456 .. 429 458 .. 0.85 12 ? 3.5 0.0 0.34 2.3e+02 7 25 .. 474 492 .. 469 493 .. 0.86 13 ! 10.7 0.0 0.0015 1 6 29 .. 513 536 .. 509 540 .. 0.90 14 ? 6.4 0.1 0.039 27 6 29 .. 553 576 .. 549 579 .. 0.87 15 ? 1.7 0.0 1.2 8.6e+02 7 29 .. 594 616 .. 590 618 .. 0.88 16 ? 3.3 0.0 0.38 2.6e+02 7 29 .. 634 656 .. 629 660 .. 0.86 17 ? 2.8 0.0 0.54 3.7e+02 7 27 .. 681 701 .. 676 713 .. 0.75 18 ? 3.9 0.1 0.25 1.7e+02 9 41 .. 728 761 .. 721 763 .. 0.75 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.29 TPR_14 3 awlalarallalGdpdeAlelleral 28 ++ la+++ lG++ eA+++ e l FUN_002333-T1 30 GYQNLAYVFQSLGNFREAIKYHEIHL 55 67899***************977655 PP == domain 2 score: 4.6 bits; conditional E-value: 0.15 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+ l++a+ lGd +A+e+ e+ l+ FUN_002333-T1 70 AYENLGNAYQSLGDSRKAIEYHEKRLE 96 567799***************999887 PP == domain 3 score: 4.1 bits; conditional E-value: 0.21 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd +A+e+ e+ l+ FUN_002333-T1 113 NLGNAYQSLGDSRKAIEYHEKHLEIA 138 689***************99998865 PP == domain 4 score: 4.6 bits; conditional E-value: 0.15 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+ l++a+ lGd +A+e+ e+ l+ FUN_002333-T1 150 AYENLGNAYQSLGDSRKAIEYHEKRLE 176 567799***************999887 PP == domain 5 score: 2.0 bits; conditional E-value: 0.98 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd +A+e+ e+ l+ FUN_002333-T1 193 NLGTAYQSLGDSRKAIEYHEKHLE 216 5899**************998876 PP == domain 6 score: 8.5 bits; conditional E-value: 0.008 TPR_14 5 lalarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e++l+ FUN_002333-T1 232 GSLGNAYQSLGDFRKAIEYHEKILEIA 258 5799*******************9975 PP == domain 7 score: 6.3 bits; conditional E-value: 0.042 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+++A+e+ e+ l+ FUN_002333-T1 273 NLGNAYQSLGDFQKAIEYHEKHLE 296 589***************998876 PP == domain 8 score: 6.4 bits; conditional E-value: 0.038 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+++ e+ l+ FUN_002333-T1 313 NLGNAYQSLGDFRKAIKYHEKHLKIA 338 5899***************9998865 PP == domain 9 score: 3.2 bits; conditional E-value: 0.4 TPR_14 6 alarallalGdpdeAlel 23 l+ a++ lGd+ +A+e+ FUN_002333-T1 353 SLGSAYRSLGDFRKAIEY 370 5899***********986 PP == domain 10 score: 2.5 bits; conditional E-value: 0.71 TPR_14 7 larallalGdpdeAlelle 25 l++++ lGd+ +A+e+ e FUN_002333-T1 394 LGNVYQSLGDFRKAIEYHE 412 899************9866 PP == domain 11 score: 4.5 bits; conditional E-value: 0.16 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ + l+ FUN_002333-T1 433 NLGNAYQSLGDFRKAIEYHAKHLE 456 5899*************9887776 PP == domain 12 score: 3.5 bits; conditional E-value: 0.34 TPR_14 7 larallalGdpdeAlelle 25 l+ a++ lGd+ +A+e+ e FUN_002333-T1 474 LGIAYRSLGDFRKAIEYHE 492 7889***********9866 PP == domain 13 score: 10.7 bits; conditional E-value: 0.0015 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+le++l+ FUN_002333-T1 513 NLGNAYQSLGDFRKAIEYLEKGLE 536 589******************998 PP == domain 14 score: 6.4 bits; conditional E-value: 0.039 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a++ lGd+ +A+e+ e+ l+ FUN_002333-T1 553 NLGIAYRSLGDFRKAIEYHEKRLE 576 5889**************999887 PP == domain 15 score: 1.7 bits; conditional E-value: 1.2 TPR_14 7 larallalGdpdeAlellerala 29 l+ ++l lGd +A+e+ ++l+ FUN_002333-T1 594 LGIVYLSLGDCRKAIEYHAKLLE 616 7789*************999987 PP == domain 16 score: 3.3 bits; conditional E-value: 0.38 TPR_14 7 larallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ e++l+ FUN_002333-T1 634 LGIAFQSLGDFRKAIEYHEKGLQ 656 7788999************9987 PP == domain 17 score: 2.8 bits; conditional E-value: 0.54 TPR_14 7 larallalGdpdeAlellera 27 l++++ al+++d A+++++ + FUN_002333-T1 681 LGQFENALDKFDSAVKVFDTL 701 778888888888888888766 PP == domain 18 score: 3.9 bits; conditional E-value: 0.25 TPR_14 9 rallalGdpdeAlelleralal.dPddpeawlal 41 r ll+ G+ deAl +++++ a+ d+ +++++l FUN_002333-T1 728 RSLLRIGKIDEALFAADQGRAQtLSDNLWIQYKL 761 56899**************776234555555555 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.088 61 24 73 .. 8 58 .. 2 63 .. 0.74 2 ? -0.2 0.0 2.2 1.5e+03 50 76 .. 75 101 .. 68 105 .. 0.86 3 ? 5.5 0.1 0.038 26 44 78 .. 109 143 .. 78 145 .. 0.84 4 ? -0.2 0.0 2.2 1.5e+03 50 76 .. 155 181 .. 148 185 .. 0.86 5 ? 3.1 0.1 0.2 1.4e+02 45 76 .. 190 221 .. 162 224 .. 0.85 6 ! 8.4 0.0 0.0047 3.2 46 78 .. 231 263 .. 222 265 .. 0.90 7 ? 4.5 0.1 0.077 53 46 76 .. 271 301 .. 261 305 .. 0.87 8 ! 7.5 0.0 0.0087 6 46 78 .. 311 343 .. 302 345 .. 0.90 9 ! 12.4 0.0 0.00026 0.18 37 78 .. 342 383 .. 339 385 .. 0.90 10 ? 4.9 0.0 0.056 39 47 78 .. 392 423 .. 382 425 .. 0.80 11 ? 2.9 0.0 0.23 1.6e+02 46 73 .. 431 458 .. 422 464 .. 0.83 12 ? 5.5 0.0 0.037 26 46 78 .. 471 503 .. 461 505 .. 0.86 13 ? 4.7 0.0 0.064 44 46 77 .. 511 542 .. 501 545 .. 0.86 14 ? 6.9 0.0 0.014 9.5 40 77 .. 545 582 .. 541 584 .. 0.86 15 ? 5.2 0.0 0.046 31 43 78 .. 628 663 .. 597 665 .. 0.81 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.088 Rapsyn_N 24 kalrvWrkvlkkts....dredkfrllGylitahsemGkykealefslaqlnia 73 ka+ k lk t ++++ ++ l y+++ +G ++ea+++ l+ a FUN_002333-T1 8 KAIECHEKHLKITMeigdRPGEGYQNLAYVFQ---SLGNFREAIKYHEIHLEKA 58 67777777777776222256778999999987...59********987777655 PP == domain 2 score: -0.2 bits; conditional E-value: 2.2 Rapsyn_N 50 itahsemGkykealefslaqlniaeel 76 +a+ +G + a+e+ ++l+ia e+ FUN_002333-T1 75 GNAYQSLGDSRKAIEYHEKRLEIAIEV 101 5688899****************9886 PP == domain 3 score: 5.5 bits; conditional E-value: 0.038 Rapsyn_N 44 rllGylitahsemGkykealefslaqlniaeeled 78 + G l +a+ +G + a+e+ + l+ia+e+ d FUN_002333-T1 109 NAYGNLGNAYQSLGDSRKAIEYHEKHLEIAKEVSD 143 56789999************************976 PP == domain 4 score: -0.2 bits; conditional E-value: 2.2 Rapsyn_N 50 itahsemGkykealefslaqlniaeel 76 +a+ +G + a+e+ ++l+ia e+ FUN_002333-T1 155 GNAYQSLGDSRKAIEYHEKRLEIAIEV 181 5688899****************9886 PP == domain 5 score: 3.1 bits; conditional E-value: 0.2 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeel 76 G l ta+ +G + a+e+ + l+ia e+ FUN_002333-T1 190 AYGNLGTAYQSLGDSRKAIEYHEKHLEIAIEV 221 579999**********************9886 PP == domain 6 score: 8.4 bits; conditional E-value: 0.0047 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002333-T1 231 YGSLGNAYQSLGDFRKAIEYHEKILEIAKEVSD 263 688999************************976 PP == domain 7 score: 4.5 bits; conditional E-value: 0.077 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002333-T1 271 YGNLGNAYQSLGDFQKAIEYHEKHLEIAIEV 301 58889999*******************9886 PP == domain 8 score: 7.5 bits; conditional E-value: 0.0087 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+++ + l ia+e+ d FUN_002333-T1 311 YGNLGNAYQSLGDFRKAIKYHEKHLKIAKEVGD 343 588999************************865 PP == domain 9 score: 12.4 bits; conditional E-value: 0.00026 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeeled 78 dr + ++ G l a+ +G ++ a+e+ + l+ia+e+ d FUN_002333-T1 342 GDRVGEGNVYGSLGSAYRSLGDFRKAIEYQEKDLEIAKEVSD 383 5777788999*****************************976 PP == domain 10 score: 4.9 bits; conditional E-value: 0.056 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeeled 78 G l + + +G ++ a+e+ + l+ia e+ d FUN_002333-T1 392 GNLGNVYQSLGDFRKAIEYHEKNLQIAVEVGD 423 5555666789*****************99865 PP == domain 11 score: 2.9 bits; conditional E-value: 0.23 Rapsyn_N 46 lGylitahsemGkykealefslaqlnia 73 G l +a+ +G ++ a+e+ + l++a FUN_002333-T1 431 YGNLGNAYQSLGDFRKAIEYHAKHLELA 458 58889999************98888766 PP == domain 12 score: 5.5 bits; conditional E-value: 0.037 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l a+ +G ++ a+e+ + l+ia e+ d FUN_002333-T1 471 YGNLGIAYRSLGDFRKAIEYHEKDLQIAIEVGD 503 578888999*******************99865 PP == domain 13 score: 4.7 bits; conditional E-value: 0.064 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002333-T1 511 YGNLGNAYQSLGDFRKAIEYLEKGLEIAIEVG 542 68899999*******************99976 PP == domain 14 score: 6.9 bits; conditional E-value: 0.014 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaeele 77 + r G l a+ +G ++ a+e+ ++l+ia e+ FUN_002333-T1 545 VGEGRAYGNLGIAYRSLGDFRKAIEYHEKRLEIAIEVG 582 566678899999**********************9986 PP == domain 15 score: 5.2 bits; conditional E-value: 0.046 Rapsyn_N 43 frllGylitahsemGkykealefslaqlniaeeled 78 G l a +G ++ a+e+ + l+ia e+ d FUN_002333-T1 628 GSAYGSLGIAFQSLGDFRKAIEYHEKGLQIAIEVGD 663 55678899999*******************999865 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.22 1.5e+02 40 112 .. 68 140 .. 33 154 .. 0.78 2 ? 1.9 0.0 0.22 1.5e+02 16 112 .. 83 180 .. 74 187 .. 0.65 3 ! 16.1 0.1 1.1e-05 0.0073 16 152 .. 163 298 .. 154 305 .. 0.71 4 ! 23.3 0.0 7.1e-08 4.9e-05 12 155 .. 279 421 .. 275 426 .. 0.91 5 ! 14.7 0.0 2.8e-05 0.019 42 154 .. 430 540 .. 423 554 .. 0.93 6 ? 6.0 0.0 0.012 8.5 14 113 .. 561 661 .. 553 690 .. 0.84 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.22 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqe 112 ++a+ +lG a++ +gd +A + ++ ++a + ++ a+ +++ ++ G+ ++A+e ++ l+ a+e FUN_002333-T1 68 GSAYENLGNAYQSLGDSRKAIEYHEKRLEIAIEVGHRVGEGNAYGNLGNAYQSLGDSRKAIEYHEKHLEIAKE 140 6788999999999999888888777777777777777778889999999999999999999999999988887 PP == domain 2 score: 1.9 bits; conditional E-value: 0.22 TPR_MalT 16 eaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 + +a+e+ ++ L++ e + + + a+ +lG a++ +gd +A + ++ ++a++ + a+ +++ ++ G+ ++A+e ++ l+ a FUN_002333-T1 83 DSRKAIEYHEKRLEIAIEVGHRVGeGNAYGNLGNAYQSLGDSRKAIEYHEKHLEIAKEVSDRVGEGSAYENLGNAYQSLGDSRKAIEYHEKRLEIA 178 555666666666666666555555577888888888888885555555555555555544444467777788888888888888888877777776 PP TPR_MalT 111 qe 112 e FUN_002333-T1 179 IE 180 65 PP == domain 3 score: 16.1 bits; conditional E-value: 1.1e-05 TPR_MalT 16 eaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 + +a+e+ ++ L++ e + + + a+ +lG+a++ +gd +A + ++ ++a + + a+ ++++ ++ G++++A+e +++l+ a FUN_002333-T1 163 DSRKAIEYHEKRLEIAIEVGHRVGeGNAYGNLGTAYQSLGDSRKAIEYHEKHLEIAIEVRHRVGEGNAYGSLGNAYQSLGDFRKAIEYHEKILEIA 258 556666666666666666666555578889999999999995555555555555555555555568888899999999999999999999999999 PP TPR_MalT 111 qesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 +e + + g+++ l++ + +d+ +A ++ ++ ++++ FUN_002333-T1 259 KEVSDKV--GEGGAYGNLGNAYQSLGDFQKAIEYHEKHLEIA 298 9988884..778888888888888888888877777666554 PP == domain 4 score: 23.3 bits; conditional E-value: 7.1e-08 TPR_MalT 12 vsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 s g++++a+e+ ++ L++ e + + ++a+ +lG a++ +gd+ +A + ++ ++a++ ++ + +++ +r G++++A+e +++ FUN_002333-T1 279 QSLGDFQKAIEYHEKHLEIAIEVGHRVGeGSAYGNLGNAYQSLGDFRKAIKYHEKHLKIAKEVGDRVGEGNVYGSLGSAYRSLGDFRKAIEYQEKD 374 57799**************99999999889*****************999988888888888888888888999********************** PP TPR_MalT 107 lqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 l+ a+e + + g+++ l++++ +d+ +A ++ ++++q++ ++ FUN_002333-T1 375 LEIAKEVSDRV--GEGGAYGNLGNVYQSLGDFRKAIEYHEKNLQIAVEV 421 *******9995..899****************************98665 PP == domain 5 score: 14.7 bits; conditional E-value: 2.8e-05 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 a+ +lG a++ +gd+ +A + ++ +la + ++ a+ ++ +r G++++A+e ++ lq a e + +a g+++ l++ + +d FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEYHAKHLELAIAVGDRVGEGSAYGNLGIAYRSLGDFRKAIEYHEKDLQIAIEVGDRA--GEGGAYGNLGNAYQSLGD 523 6789***********************9999999999999********************************9995..999*************** PP TPR_MalT 138 LeeAeqhlqqgiqlgrq 154 + +A ++l++g++++ + FUN_002333-T1 524 FRKAIEYLEKGLEIAIE 540 ************99755 PP == domain 6 score: 6.0 bits; conditional E-value: 0.012 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ e d + a+ +lG ++l +gd +A + +++ ++a + ++ a+ +++ + G++++A+e +++lq FUN_002333-T1 561 LGDFRKAIEYHEKRLEIAIEvGDRVGEGYAYGNLGIVYLSLGDCRKAIEYHAKLLEIAIAVGDRVGEGSAYGSLGIAFQSLGDFRKAIEYHEKGLQ 656 5677777777777777643323334457788**************************999999999999999999999****************** PP TPR_MalT 109 laqes 113 a e FUN_002333-T1 657 IAIEV 661 *9875 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 1.2 8.1e+02 5 22 .. 33 50 .. 29 50 .. 0.90 2 ? 4.5 0.0 0.14 93 2 22 .. 70 90 .. 69 92 .. 0.89 3 ? 3.2 0.0 0.36 2.5e+02 6 22 .. 114 130 .. 113 132 .. 0.92 4 ? 4.5 0.0 0.14 93 2 22 .. 150 170 .. 149 172 .. 0.89 5 ? 3.0 0.0 0.41 2.8e+02 6 22 .. 194 210 .. 193 212 .. 0.92 6 ? 4.2 0.0 0.17 1.2e+02 6 27 .. 234 255 .. 233 257 .. 0.86 7 ? 4.8 0.0 0.11 77 6 22 .. 274 290 .. 273 292 .. 0.92 8 ? 3.9 0.1 0.21 1.4e+02 5 22 .. 313 330 .. 310 333 .. 0.91 9 ? 3.2 0.0 0.35 2.4e+02 6 22 .. 354 370 .. 353 370 .. 0.92 10 ? 2.2 0.0 0.71 4.9e+02 5 22 .. 393 410 .. 390 412 .. 0.90 11 ? 3.5 0.0 0.27 1.9e+02 6 22 .. 434 450 .. 432 450 .. 0.92 12 ? 4.3 0.0 0.16 1.1e+02 5 22 .. 473 490 .. 470 492 .. 0.92 13 ! 8.3 0.1 0.0083 5.7 6 25 .. 514 533 .. 513 533 .. 0.94 14 ? 4.3 0.0 0.16 1.1e+02 5 22 .. 553 570 .. 550 572 .. 0.92 15 ? 2.1 0.0 0.77 5.3e+02 5 26 .. 593 614 .. 589 617 .. 0.84 16 ? 1.3 0.0 1.4 1e+03 6 22 .. 634 650 .. 633 651 .. 0.92 17 ? 2.6 0.0 0.53 3.7e+02 5 29 .. 673 697 .. 669 700 .. 0.85 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 1.2 TPR_6 5 klalsylelgdkdeAkaa 22 +la+ ++ lg++ eA+++ FUN_002333-T1 33 NLAYVFQSLGNFREAIKY 50 79*************986 PP == domain 2 score: 4.5 bits; conditional E-value: 0.14 TPR_6 2 AllklalsylelgdkdeAkaa 22 A+ +l+ +y+ lgd +A+++ FUN_002333-T1 70 AYENLGNAYQSLGDSRKAIEY 90 56689*************986 PP == domain 3 score: 3.2 bits; conditional E-value: 0.36 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd +A+++ FUN_002333-T1 114 LGNAYQSLGDSRKAIEY 130 89************986 PP == domain 4 score: 4.5 bits; conditional E-value: 0.14 TPR_6 2 AllklalsylelgdkdeAkaa 22 A+ +l+ +y+ lgd +A+++ FUN_002333-T1 150 AYENLGNAYQSLGDSRKAIEY 170 56689*************986 PP == domain 5 score: 3.0 bits; conditional E-value: 0.41 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd +A+++ FUN_002333-T1 194 LGTAYQSLGDSRKAIEY 210 89************986 PP == domain 6 score: 4.2 bits; conditional E-value: 0.17 TPR_6 6 lalsylelgdkdeAkaalqrli 27 l+ +y+ lgd+ +A+++ ++++ FUN_002333-T1 234 LGNAYQSLGDFRKAIEYHEKIL 255 799************9866665 PP == domain 7 score: 4.8 bits; conditional E-value: 0.11 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002333-T1 274 LGNAYQSLGDFQKAIEY 290 89************986 PP == domain 8 score: 3.9 bits; conditional E-value: 0.21 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002333-T1 313 NLGNAYQSLGDFRKAIKY 330 589************986 PP == domain 9 score: 3.2 bits; conditional E-value: 0.35 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002333-T1 354 LGSAYRSLGDFRKAIEY 370 799***********986 PP == domain 10 score: 2.2 bits; conditional E-value: 0.71 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ y+ lgd+ +A+++ FUN_002333-T1 393 NLGNVYQSLGDFRKAIEY 410 58999**********986 PP == domain 11 score: 3.5 bits; conditional E-value: 0.27 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002333-T1 434 LGNAYQSLGDFRKAIEY 450 89************986 PP == domain 12 score: 4.3 bits; conditional E-value: 0.16 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002333-T1 473 NLGIAYRSLGDFRKAIEY 490 59*************986 PP == domain 13 score: 8.3 bits; conditional E-value: 0.0083 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd+ +A+++l++ FUN_002333-T1 514 LGNAYQSLGDFRKAIEYLEK 533 89****************96 PP == domain 14 score: 4.3 bits; conditional E-value: 0.16 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002333-T1 553 NLGIAYRSLGDFRKAIEY 570 59*************986 PP == domain 15 score: 2.1 bits; conditional E-value: 0.77 TPR_6 5 klalsylelgdkdeAkaalqrl 26 +l+ yl lgd +A+++ ++l FUN_002333-T1 593 NLGIVYLSLGDCRKAIEYHAKL 614 699*************986666 PP == domain 16 score: 1.3 bits; conditional E-value: 1.4 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +++ lgd+ +A+++ FUN_002333-T1 634 LGIAFQSLGDFRKAIEY 650 7999**********986 PP == domain 17 score: 2.6 bits; conditional E-value: 0.53 TPR_6 5 klalsylelgdkdeAkaalqrlikk 29 +++l y lg++++A++ +++ +k FUN_002333-T1 673 NIGLGYSSLGQFENALDKFDSAVKV 697 578889999*********9998886 PP >> DUF7542 Family of unknown function (DUF7542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.94 6.5e+02 18 36 .. 37 55 .. 33 66 .. 0.81 2 ? 4.3 0.0 0.068 47 17 35 .. 76 94 .. 70 106 .. 0.84 3 ? 4.4 0.0 0.062 43 17 35 .. 116 134 .. 110 148 .. 0.87 4 ? 4.3 0.0 0.066 46 17 35 .. 156 174 .. 149 186 .. 0.84 5 ? 4.6 0.0 0.055 38 17 36 .. 196 215 .. 190 228 .. 0.85 6 ? 1.9 0.0 0.38 2.6e+02 17 34 .. 236 253 .. 229 265 .. 0.88 7 ? -0.6 0.0 2.2 1.5e+03 17 35 .. 276 294 .. 271 306 .. 0.83 8 ? 1.2 0.0 0.6 4.2e+02 17 35 .. 316 334 .. 309 340 .. 0.87 9 ? -2.5 0.0 8.6 6e+03 17 35 .. 356 374 .. 353 380 .. 0.84 10 ? 2.5 0.0 0.25 1.7e+02 17 36 .. 396 415 .. 389 421 .. 0.86 11 ? 0.2 0.0 1.3 8.8e+02 17 34 .. 436 453 .. 431 459 .. 0.86 12 ? 1.9 0.0 0.38 2.6e+02 18 36 .. 477 495 .. 472 501 .. 0.87 13 ? 0.7 0.0 0.87 6e+02 18 35 .. 557 574 .. 553 581 .. 0.87 14 ? 1.8 0.0 0.39 2.7e+02 18 34 .. 637 653 .. 631 662 .. 0.87 15 ? -1.8 0.0 5.4 3.7e+03 14 45 .. 683 714 .. 681 715 .. 0.91 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.94 DUF7542 18 tfdslraARealddHeset 36 f+sl++ Rea++ He + FUN_002333-T1 37 VFQSLGNFREAIKYHEIHL 55 79*************9754 PP == domain 2 score: 4.3 bits; conditional E-value: 0.068 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He+ FUN_002333-T1 76 NAYQSLGDSRKAIEYHEKR 94 689*************985 PP == domain 3 score: 4.4 bits; conditional E-value: 0.062 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002333-T1 116 NAYQSLGDSRKAIEYHEKH 134 78***************86 PP == domain 4 score: 4.3 bits; conditional E-value: 0.066 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He+ FUN_002333-T1 156 NAYQSLGDSRKAIEYHEKR 174 689*************985 PP == domain 5 score: 4.6 bits; conditional E-value: 0.055 DUF7542 17 etfdslraARealddHeset 36 ++++sl++ R+a++ He++ FUN_002333-T1 196 TAYQSLGDSRKAIEYHEKHL 215 689**************865 PP == domain 6 score: 1.9 bits; conditional E-value: 0.38 DUF7542 17 etfdslraARealddHes 34 ++++sl++ R+a++ He+ FUN_002333-T1 236 NAYQSLGDFRKAIEYHEK 253 789*************96 PP == domain 7 score: -0.6 bits; conditional E-value: 2.2 DUF7542 17 etfdslraARealddHese 35 ++++sl++ +a++ He++ FUN_002333-T1 276 NAYQSLGDFQKAIEYHEKH 294 6899************986 PP == domain 8 score: 1.2 bits; conditional E-value: 0.6 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002333-T1 316 NAYQSLGDFRKAIKYHEKH 334 789*************975 PP == domain 9 score: -2.5 bits; conditional E-value: 8.6 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ e++ FUN_002333-T1 356 SAYRSLGDFRKAIEYQEKD 374 6899*********998877 PP == domain 10 score: 2.5 bits; conditional E-value: 0.25 DUF7542 17 etfdslraARealddHeset 36 + ++sl++ R+a++ He++ FUN_002333-T1 396 NVYQSLGDFRKAIEYHEKNL 415 679**************875 PP == domain 11 score: 0.2 bits; conditional E-value: 1.3 DUF7542 17 etfdslraARealddHes 34 ++++sl++ R+a++ H + FUN_002333-T1 436 NAYQSLGDFRKAIEYHAK 453 689*************86 PP == domain 12 score: 1.9 bits; conditional E-value: 0.38 DUF7542 18 tfdslraARealddHeset 36 ++ sl++ R+a++ He++ FUN_002333-T1 477 AYRSLGDFRKAIEYHEKDL 495 699*************986 PP == domain 13 score: 0.7 bits; conditional E-value: 0.87 DUF7542 18 tfdslraARealddHese 35 ++ sl++ R+a++ He+ FUN_002333-T1 557 AYRSLGDFRKAIEYHEKR 574 699************986 PP == domain 14 score: 1.8 bits; conditional E-value: 0.39 DUF7542 18 tfdslraARealddHes 34 +f+sl++ R+a++ He+ FUN_002333-T1 637 AFQSLGDFRKAIEYHEK 653 79*************97 PP == domain 15 score: -1.8 bits; conditional E-value: 5.4 DUF7542 14 efeetfdslraARealddHesetgHevdWeie 45 +fe++ d++ +A ++ d+ +s e dW+i+ FUN_002333-T1 683 QFENALDKFDSAVKVFDTLRSFLKSEDDWKIN 714 68999999************999999***996 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.3 0.0 0.058 40 37 73 .. 29 65 .. 7 66 .. 0.89 2 ? 4.9 0.0 0.038 27 38 72 .. 70 104 .. 68 106 .. 0.92 3 ? 1.3 0.0 0.48 3.3e+02 38 64 .. 110 136 .. 108 146 .. 0.87 4 ? 5.5 0.1 0.025 17 37 72 .. 149 184 .. 132 186 .. 0.86 5 ? 2.1 0.0 0.29 2e+02 38 72 .. 190 224 .. 188 226 .. 0.87 6 ? 4.0 0.0 0.074 51 38 68 .. 230 260 .. 227 266 .. 0.85 7 ? 6.3 0.0 0.015 10 38 73 .. 270 305 .. 258 306 .. 0.91 8 ? 2.5 0.0 0.21 1.5e+02 38 64 .. 310 336 .. 308 345 .. 0.86 9 ? 3.1 0.0 0.14 95 38 64 .. 390 416 .. 365 425 .. 0.80 10 ? 3.4 0.1 0.11 75 38 72 .. 430 464 .. 429 496 .. 0.83 11 ? 2.8 0.0 0.17 1.2e+02 38 67 .. 510 539 .. 508 548 .. 0.85 12 ? 1.4 0.0 0.45 3.1e+02 33 67 .. 545 579 .. 525 585 .. 0.73 13 ? 6.4 0.0 0.013 8.9 38 143 .. 590 698 .. 588 709 .. 0.73 Alignments for each domain: == domain 1 score: 4.3 bits; conditional E-value: 0.058 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 +++++la + + g++++A+k+ e +ek++ +gh + FUN_002333-T1 29 EGYQNLAYVFQSLGNFREAIKYHEIHLEKAIEAGHRV 65 6899******************************975 PP == domain 2 score: 4.9 bits; conditional E-value: 0.038 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+e+l++ y + gd ++A+++ e+ +e ++ gh FUN_002333-T1 70 AYENLGNAYQSLGDSRKAIEYHEKRLEIAIEVGHR 104 799*********************99999999987 PP == domain 3 score: 1.3 bits; conditional E-value: 0.48 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd ++A+++ e+ +e FUN_002333-T1 110 AYGNLGNAYQSLGDSRKAIEYHEKHLE 136 7889*****************999876 PP == domain 4 score: 5.5 bits; conditional E-value: 0.025 RPN7 37 raledlaehyakigdlenAlkayerarekttslghk 72 a+e+l++ y + gd ++A+++ e+ +e ++ gh FUN_002333-T1 149 SAYENLGNAYQSLGDSRKAIEYHEKRLEIAIEVGHR 184 689**********************99999999987 PP == domain 5 score: 2.1 bits; conditional E-value: 0.29 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l+ y + gd ++A+++ e+ +e ++ h FUN_002333-T1 190 AYGNLGTAYQSLGDSRKAIEYHEKHLEIAIEVRHR 224 7889********************99988777765 PP == domain 6 score: 4.0 bits; conditional E-value: 0.074 RPN7 38 aledlaehyakigdlenAlkayerarektts 68 a+ l++ y + gd+++A+++ e+++e + FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKILEIAKE 260 678899*******************986655 PP == domain 7 score: 6.3 bits; conditional E-value: 0.015 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002333-T1 270 AYGNLGNAYQSLGDFQKAIEYHEKHLEIAIEVGHRV 305 6789***********************999999875 PP == domain 8 score: 2.5 bits; conditional E-value: 0.21 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+k+ e+ ++ FUN_002333-T1 310 AYGNLGNAYQSLGDFRKAIKYHEKHLK 336 6889*****************998765 PP == domain 9 score: 3.1 bits; conditional E-value: 0.14 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ ++ FUN_002333-T1 390 AYGNLGNVYQSLGDFRKAIEYHEKNLQ 416 7889*****************998766 PP == domain 10 score: 3.4 bits; conditional E-value: 0.11 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + gd+++A+++ ++ +e +++ g FUN_002333-T1 430 AYGNLGNAYQSLGDFRKAIEYHAKHLELAIAVGDR 464 5779999***************9999988877765 PP == domain 11 score: 2.8 bits; conditional E-value: 0.17 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ +l++ y + gd+++A++++e+ +e ++ FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIAI 539 57899*****************99877655 PP == domain 12 score: 1.4 bits; conditional E-value: 0.45 RPN7 33 eeirraledlaehyakigdlenAlkayerarektt 67 ra+ +l+ y + gd+++A+++ e+ +e ++ FUN_002333-T1 545 VGEGRAYGNLGIAYRSLGDFRKAIEYHEKRLEIAI 579 555678999999**************999877655 PP == domain 13 score: 6.4 bits; conditional E-value: 0.013 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffn...dwalvskylekaksliekggdwerrnrlkvyeGlaalairkfk 130 a+ +l+ y++ gd+++A+++ ++++e +++ g + + +gi+f+ d+ ++ +y ek ++ + gd+ + + Gl + + ++f+ FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEYHAKLLEIAIAVGDRVGEGSAYGSLGIAFQslgDFRKAIEYHEKGLQIAIEVGDRAGEGESHHNIGLGYSSLGQFE 685 56789999*******************999999998888888888887752225566666666666666667777777777777777777777777 PP RPN7 131 eAakllldslstf 143 A +++ +++ f FUN_002333-T1 686 NALDKFDSAVKVF 698 7777776666665 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.06 41 218 243 .. 71 96 .. 49 100 .. 0.87 2 ? 4.8 0.0 0.033 23 219 246 .. 112 139 .. 108 143 .. 0.88 3 ? 3.6 0.0 0.076 53 218 243 .. 151 176 .. 146 180 .. 0.88 4 ? 5.6 0.0 0.019 13 219 243 .. 192 216 .. 188 220 .. 0.89 5 ? 1.0 0.0 0.48 3.3e+02 219 245 .. 232 258 .. 227 263 .. 0.84 6 ? 1.5 0.0 0.33 2.3e+02 220 243 .. 273 296 .. 270 300 .. 0.88 7 ? 3.5 0.0 0.083 58 219 246 .. 312 339 .. 307 343 .. 0.89 8 ? 3.1 0.0 0.11 74 217 245 .. 350 378 .. 344 383 .. 0.86 9 ? -0.2 0.1 1.1 7.8e+02 220 242 .. 433 455 .. 429 459 .. 0.87 10 ? -0.7 0.0 1.6 1.1e+03 219 243 .. 472 496 .. 468 503 .. 0.83 11 ? 0.3 0.0 0.79 5.5e+02 220 241 .. 513 534 .. 509 540 .. 0.85 12 ? -0.3 0.0 1.2 8.1e+02 219 243 .. 552 576 .. 548 580 .. 0.86 13 ? -2.5 0.0 5.3 3.7e+03 219 241 .. 632 654 .. 628 659 .. 0.82 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.06 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 +e ++ A+ lg++rkA +y +k+++ FUN_002333-T1 71 YENLGNAYQSLGDSRKAIEYHEKRLE 96 67899****************99875 PP == domain 2 score: 4.8 bits; conditional E-value: 0.033 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg++rkA +y +k+++ +k FUN_002333-T1 112 GNLGNAYQSLGDSRKAIEYHEKHLEIAK 139 56899*****************998766 PP == domain 3 score: 3.6 bits; conditional E-value: 0.076 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 +e ++ A+ lg++rkA +y +k+++ FUN_002333-T1 151 YENLGNAYQSLGDSRKAIEYHEKRLE 176 577999***************99875 PP == domain 4 score: 5.6 bits; conditional E-value: 0.019 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + +++A+ lg++rkA +y +k+++ FUN_002333-T1 192 GNLGTAYQSLGDSRKAIEYHEKHLE 216 6799*****************9976 PP == domain 5 score: 1.0 bits; conditional E-value: 0.48 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqn 245 + ++ A+ lg+ rkA +y +k ++ + FUN_002333-T1 232 GSLGNAYQSLGDFRKAIEYHEKILEIA 258 67899**************99966554 PP == domain 6 score: 1.5 bits; conditional E-value: 0.33 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ +kA +y +k+++ FUN_002333-T1 273 NLGNAYQSLGDFQKAIEYHEKHLE 296 6899****************9976 PP == domain 7 score: 3.5 bits; conditional E-value: 0.083 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002333-T1 312 GNLGNAYQSLGDFRKAIKYHEKHLKIAK 339 67899*****************999876 PP == domain 8 score: 3.1 bits; conditional E-value: 0.11 TPR_15 217 LweayAaAllllgqnrkALpyfrkkaaqn 245 ++ +++A+ lg+ rkA +y +k ++ + FUN_002333-T1 350 VYGSLGSAYRSLGDFRKAIEYQEKDLEIA 378 57889****************99977665 PP == domain 9 score: -0.2 bits; conditional E-value: 1.1 TPR_15 220 ayAaAllllgqnrkALpyfrkka 242 ++ A+ lg+ rkA +y k++ FUN_002333-T1 433 NLGNAYQSLGDFRKAIEYHAKHL 455 6899**************99876 PP == domain 10 score: -0.7 bits; conditional E-value: 1.6 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k ++ FUN_002333-T1 472 GNLGIAYRSLGDFRKAIEYHEKDLQ 496 567889999*********9998654 PP == domain 11 score: 0.3 bits; conditional E-value: 0.79 TPR_15 220 ayAaAllllgqnrkALpyfrkk 241 ++ A+ lg+ rkA +y++k FUN_002333-T1 513 NLGNAYQSLGDFRKAIEYLEKG 534 6899**************9985 PP == domain 12 score: -0.3 bits; conditional E-value: 1.2 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002333-T1 552 GNLGIAYRSLGDFRKAIEYHEKRLE 576 56889***************99875 PP == domain 13 score: -2.5 bits; conditional E-value: 5.3 TPR_15 219 eayAaAllllgqnrkALpyfrkk 241 + ++ A+ lg+ rkA +y +k FUN_002333-T1 632 GSLGIAFQSLGDFRKAIEYHEKG 654 567889999*********99985 PP >> DBD_Tnp_Mut MuDR family transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.29 2e+02 9 26 .. 37 54 .. 33 60 .. 0.88 2 ? -1.7 0.0 4.9 3.4e+03 6 22 .. 74 90 .. 72 92 .. 0.87 3 ? -1.6 0.0 4.4 3.1e+03 6 22 .. 114 130 .. 112 138 .. 0.88 4 ? -1.7 0.0 4.9 3.4e+03 6 22 .. 154 170 .. 152 172 .. 0.87 5 ? -1.6 0.0 4.6 3.2e+03 6 22 .. 194 210 .. 192 216 .. 0.88 6 ? 0.8 0.0 0.79 5.4e+02 6 22 .. 234 250 .. 231 254 .. 0.88 7 ? -2.2 0.0 6.8 4.7e+03 6 22 .. 274 290 .. 273 292 .. 0.87 8 ? 1.1 0.0 0.63 4.4e+02 6 23 .. 314 331 .. 312 339 .. 0.88 9 ? -0.3 0.0 1.7 1.2e+03 6 21 .. 354 369 .. 349 373 .. 0.86 10 ? 1.6 0.0 0.46 3.2e+02 6 23 .. 394 411 .. 391 419 .. 0.88 11 ? 2.4 0.0 0.25 1.8e+02 6 24 .. 434 452 .. 431 459 .. 0.90 12 ? 0.9 0.0 0.73 5e+02 6 23 .. 474 491 .. 472 501 .. 0.85 13 ? -0.0 0.0 1.4 9.9e+02 6 21 .. 514 529 .. 512 531 .. 0.89 14 ? 0.4 0.0 1.1 7.3e+02 6 22 .. 554 570 .. 552 574 .. 0.88 15 ? 1.0 0.0 0.68 4.7e+02 6 24 .. 594 612 .. 592 614 .. 0.89 16 ? 4.3 0.0 0.066 45 6 22 .. 634 650 .. 631 658 .. 0.90 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.29 DBD_Tnp_Mut 9 kFkdleefrkAlrkyaIa 26 +F++l +fr+A++ + I FUN_002333-T1 37 VFQSLGNFREAIKYHEIH 54 7************99886 PP == domain 2 score: -1.7 bits; conditional E-value: 4.9 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l + rkA++ FUN_002333-T1 74 LGNAYQSLGDSRKAIEY 90 69999*********975 PP == domain 3 score: -1.6 bits; conditional E-value: 4.4 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l + rkA++ FUN_002333-T1 114 LGNAYQSLGDSRKAIEY 130 68999*********986 PP == domain 4 score: -1.7 bits; conditional E-value: 4.9 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l + rkA++ FUN_002333-T1 154 LGNAYQSLGDSRKAIEY 170 69999*********975 PP == domain 5 score: -1.6 bits; conditional E-value: 4.6 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l + rkA++ FUN_002333-T1 194 LGTAYQSLGDSRKAIEY 210 68999*********986 PP == domain 6 score: 0.8 bits; conditional E-value: 0.79 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002333-T1 234 LGNAYQSLGDFRKAIEY 250 69999*********986 PP == domain 7 score: -2.2 bits; conditional E-value: 6.8 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +f+kA++ FUN_002333-T1 274 LGNAYQSLGDFQKAIEY 290 68999*********975 PP == domain 8 score: 1.1 bits; conditional E-value: 0.63 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002333-T1 314 LGNAYQSLGDFRKAIKYH 331 69999*********9865 PP == domain 9 score: -0.3 bits; conditional E-value: 1.7 DBD_Tnp_Mut 6 vGlkFkdleefrkAlr 21 +G + +l +frkA++ FUN_002333-T1 354 LGSAYRSLGDFRKAIE 369 79999*********96 PP == domain 10 score: 1.6 bits; conditional E-value: 0.46 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G ++++l +frkA++ + FUN_002333-T1 394 LGNVYQSLGDFRKAIEYH 411 7999**********9865 PP == domain 11 score: 2.4 bits; conditional E-value: 0.25 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002333-T1 434 LGNAYQSLGDFRKAIEYHA 452 79999**********9887 PP == domain 12 score: 0.9 bits; conditional E-value: 0.73 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G + +l +frkA++ + FUN_002333-T1 474 LGIAYRSLGDFRKAIEYH 491 69999**********876 PP == domain 13 score: -0.0 bits; conditional E-value: 1.4 DBD_Tnp_Mut 6 vGlkFkdleefrkAlr 21 +G +++l +frkA++ FUN_002333-T1 514 LGNAYQSLGDFRKAIE 529 69999*********96 PP == domain 14 score: 0.4 bits; conditional E-value: 1.1 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002333-T1 554 LGIAYRSLGDFRKAIEY 570 69999*********986 PP == domain 15 score: 1.0 bits; conditional E-value: 0.68 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G ++ +l ++rkA++ +a FUN_002333-T1 594 LGIVYLSLGDCRKAIEYHA 612 689999*********9887 PP == domain 16 score: 4.3 bits; conditional E-value: 0.066 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G F++l +frkA++ FUN_002333-T1 634 LGIAFQSLGDFRKAIEY 650 799***********986 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 2.1 1.5e+03 14 31 .. 38 55 .. 32 59 .. 0.80 2 ? -1.4 0.0 5.3 3.6e+03 14 31 .. 78 95 .. 76 97 .. 0.87 3 ? -1.4 0.0 5.3 3.7e+03 14 31 .. 118 135 .. 116 137 .. 0.87 4 ? -1.3 0.0 4.9 3.4e+03 14 31 .. 158 175 .. 156 178 .. 0.87 5 ? 0.0 0.0 1.9 1.3e+03 12 31 .. 196 215 .. 192 218 .. 0.87 6 ? 0.5 0.0 1.3 9.3e+02 14 30 .. 238 254 .. 236 257 .. 0.87 7 ? 0.2 0.0 1.7 1.2e+03 14 31 .. 278 295 .. 276 298 .. 0.88 8 ? 0.5 0.0 1.3 9.2e+02 14 31 .. 318 335 .. 315 338 .. 0.89 9 ? -1.3 0.0 4.8 3.3e+03 14 31 .. 358 375 .. 357 377 .. 0.86 10 ? 2.8 0.0 0.25 1.8e+02 14 31 .. 398 415 .. 396 418 .. 0.90 11 ? -1.8 0.0 7.1 4.9e+03 14 29 .. 438 453 .. 436 455 .. 0.84 12 ? 3.2 0.0 0.2 1.4e+02 12 31 .. 476 495 .. 472 498 .. 0.88 13 ? 3.3 0.0 0.18 1.2e+02 12 31 .. 556 575 .. 552 579 .. 0.88 14 ? -1.7 0.0 6.4 4.4e+03 12 30 .. 596 614 .. 593 617 .. 0.84 15 ? 0.8 0.0 1.1 7.7e+02 12 31 .. 636 655 .. 635 658 .. 0.86 16 ? 4.2 0.0 0.094 65 12 27 .. 676 691 .. 655 697 .. 0.82 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2.1 DUF2977 14 YvlvGgledgidvdednl 31 + G ++++i ++e l FUN_002333-T1 38 FQSLGNFREAIKYHEIHL 55 5568**********9655 PP == domain 2 score: -1.4 bits; conditional E-value: 5.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++i+++e+ l FUN_002333-T1 78 YQSLGDSRKAIEYHEKRL 95 778999********9877 PP == domain 3 score: -1.4 bits; conditional E-value: 5.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++i+++e+ l FUN_002333-T1 118 YQSLGDSRKAIEYHEKHL 135 778999********9876 PP == domain 4 score: -1.3 bits; conditional E-value: 4.9 DUF2977 14 YvlvGgledgidvdednl 31 Y G +++i+++e+ l FUN_002333-T1 158 YQSLGDSRKAIEYHEKRL 175 778999*********987 PP == domain 5 score: 0.0 bits; conditional E-value: 1.9 DUF2977 12 isYvlvGgledgidvdednl 31 + Y G +++i+++e+ l FUN_002333-T1 196 TAYQSLGDSRKAIEYHEKHL 215 679999***********987 PP == domain 6 score: 0.5 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++e+ FUN_002333-T1 238 YQSLGDFRKAIEYHEKI 254 7889**********976 PP == domain 7 score: 0.2 bits; conditional E-value: 1.7 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002333-T1 278 YQSLGDFQKAIEYHEKHL 295 7789***********987 PP == domain 8 score: 0.5 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i ++e+ l FUN_002333-T1 318 YQSLGDFRKAIKYHEKHL 335 7889**********9987 PP == domain 9 score: -1.3 bits; conditional E-value: 4.8 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002333-T1 358 YRSLGDFRKAIEYQEKDL 375 7779*********99876 PP == domain 10 score: 2.8 bits; conditional E-value: 0.25 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+nl FUN_002333-T1 398 YQSLGDFRKAIEYHEKNL 415 6779************98 PP == domain 11 score: -1.8 bits; conditional E-value: 7.1 DUF2977 14 YvlvGgledgidvded 29 Y G ++++i+++ + FUN_002333-T1 438 YQSLGDFRKAIEYHAK 453 7789*********965 PP == domain 12 score: 3.2 bits; conditional E-value: 0.2 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002333-T1 476 IAYRSLGDFRKAIEYHEKDL 495 89999***********9877 PP == domain 13 score: 3.3 bits; conditional E-value: 0.18 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002333-T1 556 IAYRSLGDFRKAIEYHEKRL 575 89999************987 PP == domain 14 score: -1.7 bits; conditional E-value: 6.4 DUF2977 12 isYvlvGgledgidvdedn 30 i Y G +++i+++ ++ FUN_002333-T1 596 IVYLSLGDCRKAIEYHAKL 614 67999**********9765 PP == domain 15 score: 0.8 bits; conditional E-value: 1.1 DUF2977 12 isYvlvGgledgidvdednl 31 i + G ++++i+++e+ l FUN_002333-T1 636 IAFQSLGDFRKAIEYHEKGL 655 678889**********9765 PP == domain 16 score: 4.2 bits; conditional E-value: 0.094 DUF2977 12 isYvlvGgledgidvd 27 +Y G++e+++d FUN_002333-T1 676 LGYSSLGQFENALDKF 691 69************44 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.2 0.11 74 3 53 .. 34 90 .. 33 98 .. 0.76 2 ? 2.5 0.2 0.44 3e+02 3 55 .. 74 132 .. 73 140 .. 0.67 3 ? 1.8 0.1 0.72 5e+02 3 53 .. 154 210 .. 152 220 .. 0.63 4 ? 3.8 0.1 0.16 1.1e+02 20 55 .. 215 252 .. 193 261 .. 0.54 5 ! 9.0 0.1 0.0041 2.8 3 59 .. 234 296 .. 226 300 .. 0.88 6 ? 5.6 0.1 0.047 32 3 55 .. 274 332 .. 273 340 .. 0.73 7 ? 4.0 0.2 0.15 1e+02 3 53 .. 314 370 .. 306 375 .. 0.57 8 ? 4.2 0.1 0.13 87 3 53 .. 394 450 .. 393 455 .. 0.62 9 ! 8.6 0.5 0.0051 3.6 3 53 .. 434 490 .. 433 498 .. 0.86 10 ! 15.5 0.2 3.6e-05 0.025 3 53 .. 514 570 .. 513 579 .. 0.91 11 ? 5.7 0.0 0.042 29 3 58 .. 554 615 .. 554 621 .. 0.80 12 ? 3.3 0.0 0.23 1.6e+02 3 53 .. 594 650 .. 593 658 .. 0.67 13 ? 0.7 0.0 1.6 1.1e+03 7 27 .. 678 698 .. 673 709 .. 0.78 14 ? -1.2 0.1 6.1 4.2e+03 5 22 .. 728 745 .. 724 755 .. 0.74 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.11 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 la + +g++++A+++ e l++ A+ +lG a+ +g+ +A+++ FUN_002333-T1 34 LAYVFQSLGNFREAIKYHEIHLEKAieaghrVGEGSAYENLGNAYQSLGDSRKAIEY 90 678888999999999985555555555559966889999999999999998888854 PP == domain 2 score: 2.5 bits; conditional E-value: 0.44 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayr 55 l++a+ +gd + A+++ le a++ + A+ +lG a+ +g+ +A+++ + FUN_002333-T1 74 LGNAYQSLGDSRKAIEYhekrLEIAIEVGhrVGEGNAYGNLGNAYQSLGDSRKAIEYHE 132 67888888888888754222277777777775567777778877777777777777655 PP == domain 3 score: 1.8 bits; conditional E-value: 0.72 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd + A+++ le a++ + A+ +lG a+ +g+ +A+++ FUN_002333-T1 154 LGNAYQSLGDSRKAIEYhekrLEIAIEVGhrVGEGNAYGNLGTAYQSLGDSRKAIEY 210 688888888888887642222666666666644666666666666666666666665 PP == domain 4 score: 3.8 bits; conditional E-value: 0.16 TPR_16 20 leaalrrn..PeaaaAllglGlallrqgrlaeAaaayr 55 le a++ + A+ lG a+ +g++ +A+++ + FUN_002333-T1 215 LEIAIEVRhrVGEGNAYGSLGNAYQSLGDFRKAIEYHE 252 55555555554455555556666655566555555544 PP == domain 5 score: 9.0 bits; conditional E-value: 0.0041 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ e l+ A+ +lG a+ +g++++A+++ ++ l+ FUN_002333-T1 234 LGNAYQSLGDFRKAIEYHEKILEIAkevsdkVGEGGAYGNLGNAYQSLGDFQKAIEYHEKHLE 296 799999999999999999988888889999977899*******************98777665 PP == domain 6 score: 5.6 bits; conditional E-value: 0.047 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayr 55 l++a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ + FUN_002333-T1 274 LGNAYQSLGDFQKAIEYhekhLEIAIEVGhrVGEGSAYGNLGNAYQSLGDFRKAIKYHE 332 78888889999999865444477777777886678888888888888888888886655 PP == domain 7 score: 4.0 bits; conditional E-value: 0.15 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ e l+ + lG a+ +g++ +A+++ FUN_002333-T1 314 LGNAYQSLGDFRKAIKYHEKHLKIAkevgdrVGEGNVYGSLGSAYRSLGDFRKAIEY 370 566666666666666654443333344444433445555555555555555555554 PP == domain 8 score: 4.2 bits; conditional E-value: 0.13 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++ + +gd++ A+++ l+ a++ + A+ +lG a+ +g++ +A+++ FUN_002333-T1 394 LGNVYQSLGDFRKAIEYheknLQIAVEVGdrAGEGGAYGNLGNAYQSLGDFRKAIEY 450 567777777777776643333555666666655666777777777777776666654 PP == domain 9 score: 8.6 bits; conditional E-value: 0.0051 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ + l+ A+ +lG a+ +g++ +A+++ FUN_002333-T1 434 LGNAYQSLGDFRKAIEYHAKHLELAiavgdrVGEGSAYGNLGIAYRSLGDFRKAIEY 490 899***********9987777777777778877999******************976 PP == domain 10 score: 15.5 bits; conditional E-value: 3.6e-05 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++le l+ +A+ +lG a+ +g++ +A+++ FUN_002333-T1 514 LGNAYQSLGDFRKAIEYLEKGLEIAievgdrVGEGRAYGNLGIAYRSLGDFRKAIEY 570 89*****************9999999999**7799********************65 PP == domain 11 score: 5.7 bits; conditional E-value: 0.042 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a++ +gd++ A+++ le a++ + A+ +lG ++l +g+ +A+++ +++l FUN_002333-T1 554 LGIAYRSLGDFRKAIEYhekrLEIAIEVGdrVGEGYAYGNLGIVYLSLGDCRKAIEYHAKLL 615 68899999999999864333399999999997789999999999999999999998766665 PP == domain 12 score: 3.3 bits; conditional E-value: 0.23 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l+ +l +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ FUN_002333-T1 594 LGIVYLSLGDCRKAIEYhaklLEIAIAVGdrVGEGSAYGSLGIAFQSLGDFRKAIEY 650 677888888888887652222555555557755777888888888888888887765 PP == domain 13 score: 0.7 bits; conditional E-value: 1.6 TPR_16 7 alaagdyddAaaaleaalrrn 27 + +g+++ A+ ++ a++ + FUN_002333-T1 678 YSSLGQFENALDKFDSAVKVF 698 667889999999999888876 PP == domain 14 score: -1.2 bits; conditional E-value: 6.1 TPR_16 5 raalaagdyddAaaalea 22 r++l+ g+ d+A+ a+++ FUN_002333-T1 728 RSLLRIGKIDEALFAADQ 745 788888999988866666 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 2.6 1.8e+03 3 20 .. 70 87 .. 68 88 .. 0.87 2 ? 0.8 0.0 2.2 1.5e+03 3 20 .. 110 127 .. 108 128 .. 0.88 3 ? 0.6 0.0 2.6 1.8e+03 3 20 .. 150 167 .. 148 168 .. 0.87 4 ? 0.9 0.0 2.1 1.4e+03 3 20 .. 190 207 .. 188 208 .. 0.88 5 ? -0.3 0.0 5.2 3.6e+03 4 20 .. 231 247 .. 229 248 .. 0.86 6 ? 2.0 0.0 0.93 6.4e+02 3 20 .. 270 287 .. 268 289 .. 0.89 7 ? 2.1 0.0 0.88 6.1e+02 3 20 .. 310 327 .. 308 327 .. 0.88 8 ? 1.2 0.0 1.6 1.1e+03 3 20 .. 390 407 .. 388 409 .. 0.89 9 ? 2.1 0.0 0.83 5.7e+02 3 20 .. 430 447 .. 428 449 .. 0.89 10 ? 2.1 0.0 0.85 5.9e+02 3 20 .. 470 487 .. 468 489 .. 0.89 11 ? 2.3 0.0 0.72 4.9e+02 3 20 .. 510 527 .. 508 532 .. 0.88 12 ? 3.3 0.0 0.34 2.3e+02 2 20 .. 549 567 .. 548 569 .. 0.91 13 ? -0.7 0.0 6.7 4.7e+03 2 16 .. 589 603 .. 588 607 .. 0.88 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 2.6 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 70 AYENLGNAYQSLGDSRKA 87 7789**********9876 PP == domain 2 score: 0.8 bits; conditional E-value: 2.2 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 110 AYGNLGNAYQSLGDSRKA 127 6789**********9876 PP == domain 3 score: 0.6 bits; conditional E-value: 2.6 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 150 AYENLGNAYQSLGDSRKA 167 7789**********9876 PP == domain 4 score: 0.9 bits; conditional E-value: 2.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 190 AYGNLGTAYQSLGDSRKA 207 6789**********9876 PP == domain 5 score: -0.3 bits; conditional E-value: 5.2 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002333-T1 231 YGSLGNAYQSLGDFRKA 247 5679*********9877 PP == domain 6 score: 2.0 bits; conditional E-value: 0.93 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 270 AYGNLGNAYQSLGDFQKA 287 7889**********9877 PP == domain 7 score: 2.1 bits; conditional E-value: 0.88 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 310 AYGNLGNAYQSLGDFRKA 327 789***********9877 PP == domain 8 score: 1.2 bits; conditional E-value: 1.6 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ +++ lGd+ A FUN_002333-T1 390 AYGNLGNVYQSLGDFRKA 407 7889**********9887 PP == domain 9 score: 2.1 bits; conditional E-value: 0.83 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 430 AYGNLGNAYQSLGDFRKA 447 7889**********9887 PP == domain 10 score: 2.1 bits; conditional E-value: 0.85 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002333-T1 470 AYGNLGIAYRSLGDFRKA 487 789***********9887 PP == domain 11 score: 2.3 bits; conditional E-value: 0.72 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002333-T1 510 AYGNLGNAYQSLGDFRKA 527 7889**********9988 PP == domain 12 score: 3.3 bits; conditional E-value: 0.34 TPR_4 2 rallaLArallalGdldeA 20 ra+ +L+ a+ lGd+ A FUN_002333-T1 549 RAYGNLGIAYRSLGDFRKA 567 8999***********9887 PP == domain 13 score: -0.7 bits; conditional E-value: 6.7 TPR_4 2 rallaLArallalGd 16 +a+ +L+ ++l lGd FUN_002333-T1 589 YAYGNLGIVYLSLGD 603 5889**********8 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 2.4 1.6e+03 6 24 .. 74 92 .. 69 93 .. 0.82 2 ? 1.2 0.0 1.1 7.9e+02 3 24 .. 111 132 .. 110 133 .. 0.87 3 ? 0.2 0.0 2.4 1.6e+03 6 24 .. 154 172 .. 149 173 .. 0.82 4 ? -0.3 0.0 3.4 2.3e+03 3 24 .. 191 212 .. 190 213 .. 0.83 5 ? 6.7 0.0 0.02 14 3 28 .. 231 256 .. 230 257 .. 0.91 6 ? 2.4 0.0 0.46 3.1e+02 3 24 .. 271 292 .. 270 293 .. 0.87 7 ? 2.9 0.0 0.32 2.2e+02 2 24 .. 310 332 .. 309 333 .. 0.88 8 ? 3.9 0.0 0.16 1.1e+02 3 22 .. 351 370 .. 350 373 .. 0.91 9 ? 1.3 0.0 1.1 7.4e+02 3 24 .. 391 412 .. 390 413 .. 0.84 10 ? 1.5 0.0 0.92 6.3e+02 3 23 .. 431 451 .. 430 453 .. 0.86 11 ? 2.0 0.0 0.64 4.5e+02 3 24 .. 471 492 .. 469 493 .. 0.83 12 ? 3.8 0.0 0.17 1.2e+02 3 25 .. 511 533 .. 510 536 .. 0.89 13 ? 1.8 0.0 0.74 5.1e+02 3 24 .. 551 572 .. 549 573 .. 0.82 14 ? 1.0 0.0 1.3 8.8e+02 3 27 .. 591 615 .. 589 617 .. 0.79 15 ? 0.5 0.0 1.8 1.3e+03 2 25 .. 630 653 .. 629 655 .. 0.84 16 ? 1.6 0.0 0.84 5.8e+02 9 24 .. 677 692 .. 676 702 .. 0.86 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 2.4 PPR 6 lIsgycknGkleeAlelfk 24 l ++y + G+ ++A+e+++ FUN_002333-T1 74 LGNAYQSLGDSRKAIEYHE 92 6689999*********987 PP == domain 2 score: 1.2 bits; conditional E-value: 1.1 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G+ ++A+e+++ FUN_002333-T1 111 YGNLGNAYQSLGDSRKAIEYHE 132 777889*************987 PP == domain 3 score: 0.2 bits; conditional E-value: 2.4 PPR 6 lIsgycknGkleeAlelfk 24 l ++y + G+ ++A+e+++ FUN_002333-T1 154 LGNAYQSLGDSRKAIEYHE 172 6689999*********987 PP == domain 4 score: -0.3 bits; conditional E-value: 3.4 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +y + G+ ++A+e+++ FUN_002333-T1 191 YGNLGTAYQSLGDSRKAIEYHE 212 6666789999*********987 PP == domain 5 score: 6.7 bits; conditional E-value: 0.02 PPR 3 ynslIsgycknGkleeAlelfkeMke 28 y sl ++y + G++++A+e++++++e FUN_002333-T1 231 YGSLGNAYQSLGDFRKAIEYHEKILE 256 99999****************99875 PP == domain 6 score: 2.4 bits; conditional E-value: 0.46 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002333-T1 271 YGNLGNAYQSLGDFQKAIEYHE 292 777889*************987 PP == domain 7 score: 2.9 bits; conditional E-value: 0.32 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+++++ FUN_002333-T1 310 AYGNLGNAYQSLGDFRKAIKYHE 332 6888999************9987 PP == domain 8 score: 3.9 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlel 22 y sl s+y + G++++A+e+ FUN_002333-T1 351 YGSLGSAYRSLGDFRKAIEY 370 99999************986 PP == domain 9 score: 1.3 bits; conditional E-value: 1.1 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002333-T1 391 YGNLGNVYQSLGDFRKAIEYHE 412 6777789999*********987 PP == domain 10 score: 1.5 bits; conditional E-value: 0.92 PPR 3 ynslIsgycknGkleeAlelf 23 y l ++y + G++++A+e++ FUN_002333-T1 431 YGNLGNAYQSLGDFRKAIEYH 451 777889************975 PP == domain 11 score: 2.0 bits; conditional E-value: 0.64 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +y + G++++A+e+++ FUN_002333-T1 471 YGNLGIAYRSLGDFRKAIEYHE 492 666667999**********987 PP == domain 12 score: 3.8 bits; conditional E-value: 0.17 PPR 3 ynslIsgycknGkleeAlelfke 25 y l ++y + G++++A+e++++ FUN_002333-T1 511 YGNLGNAYQSLGDFRKAIEYLEK 533 777889*************9986 PP == domain 13 score: 1.8 bits; conditional E-value: 0.74 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +y + G++++A+e+++ FUN_002333-T1 551 YGNLGIAYRSLGDFRKAIEYHE 572 556667999**********987 PP == domain 14 score: 1.0 bits; conditional E-value: 1.3 PPR 3 ynslIsgycknGkleeAlelfkeMk 27 y l +y + G++++A+e++ +++ FUN_002333-T1 591 YGNLGIVYLSLGDCRKAIEYHAKLL 615 556666899**********987765 PP == domain 15 score: 0.5 bits; conditional E-value: 1.8 PPR 2 tynslIsgycknGkleeAlelfke 25 +y sl ++ + G++++A+e++++ FUN_002333-T1 630 AYGSLGIAFQSLGDFRKAIEYHEK 653 577777888899********9875 PP == domain 16 score: 1.6 bits; conditional E-value: 0.84 PPR 9 gycknGkleeAlelfk 24 gy++ G++e Al+ f+ FUN_002333-T1 677 GYSSLGQFENALDKFD 692 8999999999998776 PP >> BAG6 BCL2-associated athanogene 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.1 7.7e+02 53 78 .. 69 94 .. 53 101 .. 0.82 2 ? -0.7 0.0 2.5 1.7e+03 41 68 .. 95 124 .. 76 130 .. 0.71 3 ? 6.7 0.0 0.013 8.8 31 78 .. 127 174 .. 114 178 .. 0.78 4 ? 1.9 0.0 0.38 2.6e+02 39 72 .. 213 248 .. 194 253 .. 0.72 5 ? 2.3 0.0 0.3 2e+02 38 71 .. 252 287 .. 246 296 .. 0.81 6 ? 1.0 0.0 0.75 5.1e+02 47 73 .. 301 329 .. 286 336 .. 0.74 7 ? 0.2 0.0 1.4 9.4e+02 39 72 .. 333 368 .. 328 373 .. 0.78 8 ? 3.7 0.0 0.11 76 33 72 .. 369 408 .. 357 417 .. 0.82 9 ? 0.2 0.0 1.3 9.1e+02 49 72 .. 423 448 .. 409 454 .. 0.73 10 ? -0.2 0.0 1.7 1.2e+03 54 70 .. 510 526 .. 486 534 .. 0.76 11 ? -1.2 0.0 3.6 2.5e+03 46 78 .. 540 574 .. 527 577 .. 0.79 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.1 BAG6 53 EalhllshalhalSDlrlnlsqpppR 78 a+ +l++a+ +l+D r +++ + R FUN_002333-T1 69 SAYENLGNAYQSLGDSRKAIEYHEKR 94 37999**********88887777666 PP == domain 2 score: -0.7 bits; conditional E-value: 2.5 BAG6 41 reedqrildrvsE..alhllshalhalSDl 68 +e + ++ rv+E a+ +l++a+ +l+D FUN_002333-T1 95 LEIAIEVGHRVGEgnAYGNLGNAYQSLGDS 124 5555556666765448999********995 PP == domain 3 score: 6.7 bits; conditional E-value: 0.013 BAG6 31 tadennnteereedqrildrvsE..alhllshalhalSDlrlnlsqpppR 78 ++++ ++++e + ++ drv+E a+ +l++a+ +l+D r +++ + R FUN_002333-T1 127 AIEYH--EKHLEIAKEVSDRVGEgsAYENLGNAYQSLGDSRKAIEYHEKR 174 44444..5779999*******997789************88877776666 PP == domain 4 score: 1.9 bits; conditional E-value: 0.38 BAG6 39 eereedqrildrvsE..alhllshalhalSDlrlnl 72 +++e + ++ rv+E a+ +l++a+ +l+D r ++ FUN_002333-T1 213 KHLEIAIEVRHRVGEgnAYGSLGNAYQSLGDFRKAI 248 455666666677766448999**********98665 PP == domain 5 score: 2.3 bits; conditional E-value: 0.3 BAG6 38 teereedqrildrvsE..alhllshalhalSDlrln 71 ++ +e + ++ d+v+E a+ +l++a+ +l+D + + FUN_002333-T1 252 EKILEIAKEVSDKVGEggAYGNLGNAYQSLGDFQKA 287 566778889999999977899***********8755 PP == domain 6 score: 1.0 bits; conditional E-value: 0.75 BAG6 47 ildrvsE..alhllshalhalSDlrlnls 73 + rv+E a+ +l++a+ +l+D r +++ FUN_002333-T1 301 VGHRVGEgsAYGNLGNAYQSLGDFRKAIK 329 5566666447889**********987665 PP == domain 7 score: 0.2 bits; conditional E-value: 1.4 BAG6 39 eereedqrildrvsE..alhllshalhalSDlrlnl 72 ++++ + ++ drv+E ++ +l+ a+ +l+D r ++ FUN_002333-T1 333 KHLKIAKEVGDRVGEgnVYGSLGSAYRSLGDFRKAI 368 55666778889998766899***********98766 PP == domain 8 score: 3.7 bits; conditional E-value: 0.11 BAG6 33 dennnteereedqrildrvsE..alhllshalhalSDlrlnl 72 ++++ + +e + ++ drv+E a+ +l++++ +l+D r ++ FUN_002333-T1 369 EYQE--KDLEIAKEVSDRVGEggAYGNLGNVYQSLGDFRKAI 408 4444..66899999*****997789************98666 PP == domain 9 score: 0.2 bits; conditional E-value: 1.3 BAG6 49 drvsE..alhllshalhalSDlrlnl 72 dr++E a+ +l++a+ +l+D r ++ FUN_002333-T1 423 DRAGEggAYGNLGNAYQSLGDFRKAI 448 55555447889**********98655 PP == domain 10 score: -0.2 bits; conditional E-value: 1.7 BAG6 54 alhllshalhalSDlrl 70 a+ +l++a+ +l+D r FUN_002333-T1 510 AYGNLGNAYQSLGDFRK 526 7889**********985 PP == domain 11 score: -1.2 bits; conditional E-value: 3.6 BAG6 46 rildrvsE..alhllshalhalSDlrlnlsqpppR 78 ++ drv+E a+ +l+ a+ +l+D r +++ + R FUN_002333-T1 540 EVGDRVGEgrAYGNLGIAYRSLGDFRKAIEYHEKR 574 66788887667899***********9988887777 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.99 6.8e+02 100 170 .. 69 137 .. 34 142 .. 0.64 2 ? 0.7 0.0 0.56 3.9e+02 77 127 .. 133 176 .. 111 220 .. 0.61 3 ? 5.7 0.1 0.018 12 101 171 .. 230 298 .. 194 341 .. 0.66 4 ! 6.9 0.0 0.0071 4.9 99 171 .. 348 418 .. 323 423 .. 0.79 5 ? 3.9 0.0 0.063 43 101 171 .. 510 578 .. 486 583 .. 0.85 6 ? 4.0 0.0 0.057 39 102 172 .. 631 699 .. 598 704 .. 0.74 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.99 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqalei 170 + ye lG+ + lg +a++ ++ Lei ++ h + ++++ +L + y+ g ++a +++++ lei FUN_002333-T1 69 SAYENLGNAYQSLGDSRKAIEYHEKRLEIA---IEVGHRVgEGNAYGNLGNAYQSLGDSRKAIEYHEKHLEI 137 578888888888888888888888888774...333443312445555555555555555555555555555 PP == domain 2 score: 0.7 bits; conditional E-value: 0.56 TPR_NPHP3 77 aYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLe 127 ++l+ +k++ d v++ + +++ + y++lG +a++ ++ Le FUN_002333-T1 133 KHLEIAKEVSDRVGEGSAYENLGNAYQSLG-------DSRKAIEYHEKRLE 176 444445555555444444444444444444.......44444444444444 PP == domain 3 score: 5.7 bits; conditional E-value: 0.018 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 y +lG+ + lg +a++ ++ Lei + D+ + ++ +L + y+ g f++a +++++ lei FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKILEIAKEV--SDKVGEGGAYGNLGNAYQSLGDFQKAIEYHEKHLEIA 298 56666666666666666666666666666555..4555556666667777777777777777776666664 PP == domain 4 score: 6.9 bits; conditional E-value: 0.0071 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 ++y +lG + lg +a++ ++ Lei + D + ++ +L ++y+ g f++a +++++ l+i FUN_002333-T1 348 GNVYGSLGSAYRSLGDFRKAIEYQEKDLEIAKEV--SDRVGEGGAYGNLGNVYQSLGDFRKAIEYHEKNLQIA 418 5789999999999999999999999999998887..5677778899999999999999999999999999885 PP == domain 5 score: 3.9 bits; conditional E-value: 0.063 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 y lG+ + lg +a++ L++ Lei + D +r++ +L y g f++a +++++ lei FUN_002333-T1 510 AYGNLGNAYQSLGDFRKAIEYLEKGLEIAIEV--GDRVGEGRAYGNLGIAYRSLGDFRKAIEYHEKRLEIA 578 58889999999999999999999999997666..5777778999999999999999999999999988875 PP == domain 6 score: 4.0 bits; conditional E-value: 0.057 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 y +lG + lg +a++ ++ L i + D ++s+h++ y+ g+f++a + + a+++++ FUN_002333-T1 631 YGSLGIAFQSLGDFRKAIEYHEKGLQIAIEV--GDRAGEGESHHNIGLGYSSLGQFENALDKFDSAVKVFD 699 5555555555555555555555555554433..57777899999999999*******99999999999876 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.4 1.7e+03 32 56 .. 31 55 .. 26 64 .. 0.79 2 ? -2.3 0.0 9.4 6.5e+03 34 51 .. 73 90 .. 69 98 .. 0.75 3 ? -0.6 0.0 2.8 1.9e+03 34 60 .. 113 139 .. 109 147 .. 0.80 4 ? -2.0 0.0 7.7 5.3e+03 33 51 .. 152 170 .. 146 178 .. 0.73 5 ? -0.7 0.0 3.2 2.2e+03 33 57 .. 192 216 .. 189 223 .. 0.81 6 ? 4.5 0.1 0.073 50 30 54 .. 269 293 .. 234 300 .. 0.60 7 ? 1.4 0.0 0.66 4.6e+02 32 58 .. 311 337 .. 308 345 .. 0.78 8 ? -0.7 0.0 3.1 2.1e+03 36 53 .. 355 372 .. 351 385 .. 0.75 9 ? 3.0 0.0 0.22 1.5e+02 3 51 .. 396 450 .. 394 461 .. 0.68 10 ? 1.9 0.0 0.48 3.3e+02 32 51 .. 471 490 .. 468 507 .. 0.80 11 ? 7.0 0.0 0.012 8.4 32 58 .. 511 537 .. 504 544 .. 0.86 12 ? 2.0 0.0 0.45 3.1e+02 32 51 .. 551 570 .. 547 582 .. 0.84 13 ? 0.6 0.0 1.2 8.6e+02 31 51 .. 590 610 .. 587 619 .. 0.85 14 ? 0.9 0.0 0.95 6.6e+02 35 51 .. 634 650 .. 629 664 .. 0.85 15 ? -0.2 0.0 2.1 1.5e+03 36 56 .. 675 695 .. 672 699 .. 0.85 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.4 TPR_9 32 rrdrGllyaqlgcleaAladLeayl 56 +++ + + + lg++ +A+++ e l FUN_002333-T1 31 YQNLAYVFQSLGNFREAIKYHEIHL 55 57789999*********98765555 PP == domain 2 score: -2.3 bits; conditional E-value: 9.4 TPR_9 34 drGllyaqlgcleaAlad 51 + G +y+ lg+ +A+++ FUN_002333-T1 73 NLGNAYQSLGDSRKAIEY 90 678889999999998876 PP == domain 3 score: -0.6 bits; conditional E-value: 2.8 TPR_9 34 drGllyaqlgcleaAladLeaylalap 60 + G +y+ lg+ +A+++ e+ l++a FUN_002333-T1 113 NLGNAYQSLGDSRKAIEYHEKHLEIAK 139 67899**********999888887765 PP == domain 4 score: -2.0 bits; conditional E-value: 7.7 TPR_9 33 rdrGllyaqlgcleaAlad 51 + G +y+ lg+ +A+++ FUN_002333-T1 152 ENLGNAYQSLGDSRKAIEY 170 5667788888888888876 PP == domain 5 score: -0.7 bits; conditional E-value: 3.2 TPR_9 33 rdrGllyaqlgcleaAladLeayla 57 + G +y+ lg+ +A+++ e+ l+ FUN_002333-T1 192 GNLGTAYQSLGDSRKAIEYHEKHLE 216 57899***********998666655 PP == domain 6 score: 4.5 bits; conditional E-value: 0.073 TPR_9 30 eerrdrGllyaqlgcleaAladLea 54 + + + G +y+ lg++++A+++ e+ FUN_002333-T1 269 GAYGNLGNAYQSLGDFQKAIEYHEK 293 4566788889999999999887655 PP == domain 7 score: 1.4 bits; conditional E-value: 0.66 TPR_9 32 rrdrGllyaqlgcleaAladLeaylal 58 + + G +y+ lg++ +A+++ e+ l++ FUN_002333-T1 311 YGNLGNAYQSLGDFRKAIKYHEKHLKI 337 5678999**********9987766655 PP == domain 8 score: -0.7 bits; conditional E-value: 3.1 TPR_9 36 GllyaqlgcleaAladLe 53 G++y lg++ +A+++ e FUN_002333-T1 355 GSAYRSLGDFRKAIEYQE 372 888999999999998655 PP == domain 9 score: 3.0 bits; conditional E-value: 0.22 TPR_9 3 aiyireedleralavverllll......aPddpeerrdrGllyaqlgcleaAlad 51 + y++ d+ +a+++ e l++ + + + + + G +y+ lg++ +A+++ FUN_002333-T1 396 NVYQSLGDFRKAIEYHEKNLQIavevgdRAGEGGAYGNLGNAYQSLGDFRKAIEY 450 5566666666666666666666555555566666777888888888888888875 PP == domain 10 score: 1.9 bits; conditional E-value: 0.48 TPR_9 32 rrdrGllyaqlgcleaAlad 51 + + G++y lg++ +A+++ FUN_002333-T1 471 YGNLGIAYRSLGDFRKAIEY 490 6688*************985 PP == domain 11 score: 7.0 bits; conditional E-value: 0.012 TPR_9 32 rrdrGllyaqlgcleaAladLeaylal 58 + + G +y+ lg++ +A+++Le+ l++ FUN_002333-T1 511 YGNLGNAYQSLGDFRKAIEYLEKGLEI 537 567899****************87765 PP == domain 12 score: 2.0 bits; conditional E-value: 0.45 TPR_9 32 rrdrGllyaqlgcleaAlad 51 + + G++y lg++ +A+++ FUN_002333-T1 551 YGNLGIAYRSLGDFRKAIEY 570 6789*************997 PP == domain 13 score: 0.6 bits; conditional E-value: 1.2 TPR_9 31 errdrGllyaqlgcleaAlad 51 + + G++y lg+ +A+++ FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEY 610 57789*************986 PP == domain 14 score: 0.9 bits; conditional E-value: 0.95 TPR_9 35 rGllyaqlgcleaAlad 51 G++ + lg++ +A+++ FUN_002333-T1 634 LGIAFQSLGDFRKAIEY 650 69************997 PP == domain 15 score: -0.2 bits; conditional E-value: 2.1 TPR_9 36 GllyaqlgcleaAladLeayl 56 Gl y lg++e Al+ ++ ++ FUN_002333-T1 675 GLGYSSLGQFENALDKFDSAV 695 788999*********998765 PP >> DUF4810 Domain of unknown function (DUF4810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.3 0.093 64 6 70 .. 30 93 .. 28 98 .. 0.86 2 ? 3.8 0.3 0.17 1.2e+02 19 70 .. 81 133 .. 69 142 .. 0.83 3 ? 4.6 0.1 0.1 71 19 70 .. 121 173 .. 109 177 .. 0.85 4 ? 5.3 0.2 0.059 41 19 70 .. 161 213 .. 148 217 .. 0.84 5 ? 7.0 0.1 0.018 12 19 70 .. 241 293 .. 230 298 .. 0.86 6 ? 4.2 0.0 0.14 94 19 70 .. 321 373 .. 309 381 .. 0.87 7 ? 5.4 0.0 0.054 38 21 70 .. 363 413 .. 356 417 .. 0.85 8 ? 2.8 0.1 0.35 2.4e+02 20 68 .. 402 451 .. 389 458 .. 0.64 9 ? 2.7 0.0 0.38 2.6e+02 20 70 .. 442 493 .. 429 497 .. 0.80 10 ? 3.7 0.0 0.2 1.3e+02 23 70 .. 485 533 .. 478 537 .. 0.79 11 ? 5.4 0.0 0.057 39 21 68 .. 563 611 .. 551 614 .. 0.88 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.093 DUF4810 6 dYqdalyeyykeeeedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +Yq+ y + ++ + i+ +e ++eka ++g++v G y +lG y + G++ kaie+ ek FUN_002333-T1 30 GYQNLAYVFQS--LGNFREAIKYHEIHLEKAIEAGHRVGEGsAYENLGNAYQSLGDSRKAIEYHEK 93 67777776555..588999999******************955889***************99765 PP == domain 2 score: 3.8 bits; conditional E-value: 0.17 DUF4810 19 eedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d+ k ie +ek +e a + g++v G y +lG y + G++ kaie+ ek FUN_002333-T1 81 LGDSRKAIEYHEKRLEIAIEVGHRVGEGnAYGNLGNAYQSLGDSRKAIEYHEK 133 5678889999999999999999999999669*****************99876 PP == domain 3 score: 4.6 bits; conditional E-value: 0.1 DUF4810 19 eedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d+ k ie +ek++e a++ +v G y +lG y + G++ kaie+ ek FUN_002333-T1 121 LGDSRKAIEYHEKHLEIAKEVSDRVGEGsAYENLGNAYQSLGDSRKAIEYHEK 173 5678899999****************9955889**************999765 PP == domain 4 score: 5.3 bits; conditional E-value: 0.059 DUF4810 19 eedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d+ k ie +ek +e a + g++v G y +lG+ y + G++ kaie+ ek FUN_002333-T1 161 LGDSRKAIEYHEKRLEIAIEVGHRVGEGnAYGNLGTAYQSLGDSRKAIEYHEK 213 56788999999999999999999**999669*****************99775 PP == domain 5 score: 7.0 bits; conditional E-value: 0.018 DUF4810 19 eedkekqieklekdiekaeakgkkvp.PGlyAelGllyakeGkkekaieqfek 70 +d k ie +ek++e a++ kv G y +lG y + G+ +kaie+ ek FUN_002333-T1 241 LGDFRKAIEYHEKILEIAKEVSDKVGeGGAYGNLGNAYQSLGDFQKAIEYHEK 293 5678899999**********9999973579******************99875 PP == domain 6 score: 4.2 bits; conditional E-value: 0.14 DUF4810 19 eedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d k i+ +ek+++ a++ g +v G +y lG y + G+ kaie+ ek FUN_002333-T1 321 LGDFRKAIKYHEKHLKIAKEVGDRVGEGnVYGSLGSAYRSLGDFRKAIEYQEK 373 5678899999****************9988******************99766 PP == domain 7 score: 5.4 bits; conditional E-value: 0.054 DUF4810 21 dkekqieklekdiekaeakgkkvp.PGlyAelGllyakeGkkekaieqfek 70 d k ie ekd+e a++ +v G y +lG +y + G+ kaie+ ek FUN_002333-T1 363 DFRKAIEYQEKDLEIAKEVSDRVGeGGAYGNLGNVYQSLGDFRKAIEYHEK 413 5678889999999999999999973579******************99876 PP == domain 8 score: 2.8 bits; conditional E-value: 0.35 DUF4810 20 edkekqieklekdiekaeakgkkvp.PGlyAelGllyakeGkkekaieqf 68 +d k ie +ek+++ a + g + G y +lG y + G+ kaie+ FUN_002333-T1 402 GDFRKAIEYHEKNLQIAVEVGDRAGeGGAYGNLGNAYQSLGDFRKAIEYH 451 45566666777777766666555541567888888888888887777765 PP == domain 9 score: 2.7 bits; conditional E-value: 0.38 DUF4810 20 edkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d k ie + k++e a a g +v G y +lG+ y + G+ kaie+ ek FUN_002333-T1 442 GDFRKAIEYHAKHLELAIAVGDRVGEGsAYGNLGIAYRSLGDFRKAIEYHEK 493 5677888888889999999999999885599999999999999999999876 PP == domain 10 score: 3.7 bits; conditional E-value: 0.2 DUF4810 23 ekqieklekdiekaeakgkkv.pPGlyAelGllyakeGkkekaieqfek 70 k ie +ekd++ a + g + G y +lG y + G+ kaie++ek FUN_002333-T1 485 RKAIEYHEKDLQIAIEVGDRAgEGGAYGNLGNAYQSLGDFRKAIEYLEK 533 56777778888776666555514689********************986 PP == domain 11 score: 5.4 bits; conditional E-value: 0.057 DUF4810 21 dkekqieklekdiekaeakgkkvpPGl.yAelGllyakeGkkekaieqf 68 d k ie +ek +e a + g +v G+ y +lG++y++ G+ kaie+ FUN_002333-T1 563 DFRKAIEYHEKRLEIAIEVGDRVGEGYaYGNLGIVYLSLGDCRKAIEYH 611 667889999999999999********7689***************9985 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 4.1 2.9e+03 26 46 .. 109 129 .. 104 143 .. 0.83 2 ! 10.4 0.0 0.0013 0.9 4 46 .. 241 289 .. 238 297 .. 0.94 3 ? 1.1 0.0 1 7.2e+02 27 46 .. 310 329 .. 306 340 .. 0.84 4 ? -0.6 0.0 3.5 2.4e+03 5 46 .. 322 369 .. 320 377 .. 0.76 5 ? 5.9 0.1 0.033 23 5 46 .. 402 449 .. 398 456 .. 0.88 6 ! 10.6 0.1 0.0011 0.77 4 53 .. 481 536 .. 473 538 .. 0.86 7 ? -0.2 0.0 2.6 1.8e+03 26 46 .. 549 569 .. 546 578 .. 0.81 8 ? -0.3 0.0 2.8 1.9e+03 5 47 .. 562 610 .. 558 618 .. 0.58 9 ? -1.2 0.0 5.6 3.8e+03 5 20 .. 642 657 .. 640 660 .. 0.88 10 ? -1.2 0.0 5.4 3.7e+03 34 56 .. 729 751 .. 723 760 .. 0.80 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 4.1 TPR_19 26 earllLArallalgrldeAea 46 a+ +L++a+ lg+ +A++ FUN_002333-T1 109 NAYGNLGNAYQSLGDSRKAIE 129 688899999999999999987 PP == domain 2 score: 10.4 bits; conditional E-value: 0.0013 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e++l+++ + a+ +L++a+ lg++ +A++ FUN_002333-T1 241 LGDFRKAIEYHEKILEIAKEvsdkvgEGGAYGNLGNAYQSLGDFQKAIE 289 59***************999999999*********************87 PP == domain 3 score: 1.1 bits; conditional E-value: 1 TPR_19 27 arllLArallalgrldeAea 46 a+ +L++a+ lg++ +A++ FUN_002333-T1 310 AYGNLGNAYQSLGDFRKAIK 329 77899999999999999987 PP == domain 4 score: -0.6 bits; conditional E-value: 3.5 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + ++ L+ a+ lg++ +A++ FUN_002333-T1 322 GDFRKAIKYHEKHLKIAKEvgdrvgEGNVYGSLGSAYRSLGDFRKAIE 369 888888888888777777666666677777778888888888888875 PP == domain 5 score: 5.9 bits; conditional E-value: 0.033 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + a+ +L++a+ lg++ +A++ FUN_002333-T1 402 GDFRKAIEYHEKNLQIavevgdRAGEGGAYGNLGNAYQSLGDFRKAIE 449 9999999999998888777777888*********************87 PP == domain 6 score: 10.6 bits; conditional E-value: 0.0011 TPR_19 4 egdydeAlalLeqalae......dPdnaearllLArallalgrldeAealLaalpa 53 gd+ +A+++ e+ l++ + a+ +L++a+ lg++ +A++ L+++++ FUN_002333-T1 481 LGDFRKAIEYHEKDLQIaievgdRAGEGGAYGNLGNAYQSLGDFRKAIEYLEKGLE 536 589999999999966665566668889************************99876 PP == domain 7 score: -0.2 bits; conditional E-value: 2.6 TPR_19 26 earllLArallalgrldeAea 46 +a+ +L+ a+ lg++ +A++ FUN_002333-T1 549 RAYGNLGIAYRSLGDFRKAIE 569 678889999999999999876 PP == domain 8 score: -0.3 bits; conditional E-value: 2.8 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L+ ++l lg+ +A++ FUN_002333-T1 562 GDFRKAIEYHEKRLEIAIEvgdrvgEGYAYGNLGIVYLSLGDCRKAIEY 610 6666666666664443211112233566777888888888887777765 PP == domain 9 score: -1.2 bits; conditional E-value: 5.6 TPR_19 5 gdydeAlalLeqalae 20 gd+ +A+++ e+ l++ FUN_002333-T1 642 GDFRKAIEYHEKGLQI 657 9**********99986 PP == domain 10 score: -1.2 bits; conditional E-value: 5.4 TPR_19 34 allalgrldeAealLaalpaadp 56 ll+ g++deA ++++a+ FUN_002333-T1 729 SLLRIGKIDEALFAADQGRAQTL 751 58899999999999999888765 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 6.1 4.2e+03 5 27 .. 74 96 .. 72 100 .. 0.82 2 ? -0.8 0.0 3.2 2.2e+03 5 30 .. 114 139 .. 112 144 .. 0.83 3 ? -1.5 0.0 5.5 3.8e+03 5 27 .. 154 176 .. 151 180 .. 0.83 4 ? -2.2 0.0 9.3 6.4e+03 5 27 .. 194 216 .. 193 221 .. 0.80 5 ? 4.4 0.0 0.082 57 5 30 .. 234 259 .. 232 264 .. 0.89 6 ? 3.4 0.0 0.17 1.1e+02 5 27 .. 274 296 .. 272 301 .. 0.88 7 ? 5.1 0.1 0.049 34 5 30 .. 314 339 .. 312 345 .. 0.90 8 ? -0.4 0.0 2.5 1.7e+03 5 29 .. 354 378 .. 350 384 .. 0.83 9 ? 0.5 0.0 1.3 9.2e+02 5 27 .. 394 416 .. 392 420 .. 0.82 10 ? 0.8 0.0 1.1 7.6e+02 5 25 .. 434 454 .. 432 458 .. 0.87 11 ? -0.4 0.0 2.4 1.7e+03 6 27 .. 475 496 .. 472 501 .. 0.80 12 ? 1.3 0.0 0.74 5.1e+02 5 26 .. 514 535 .. 511 540 .. 0.87 13 ? -0.4 0.0 2.5 1.7e+03 6 27 .. 555 576 .. 552 580 .. 0.80 14 ? -0.5 0.0 2.7 1.9e+03 6 27 .. 635 656 .. 633 661 .. 0.79 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 6.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ + +kAi+Y e+ l+ FUN_002333-T1 74 LGNAYQSLGDSRKAIEYHEKRLE 96 788888889999*****998765 PP == domain 2 score: -0.8 bits; conditional E-value: 3.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ + +kAi+Y e+ l++ + FUN_002333-T1 114 LGNAYQSLGDSRKAIEYHEKHLEIAK 139 688888888999******99987765 PP == domain 3 score: -1.5 bits; conditional E-value: 5.5 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ + +kAi+Y e+ l+ FUN_002333-T1 154 LGNAYQSLGDSRKAIEYHEKRLE 176 789999999999*****998765 PP == domain 4 score: -2.2 bits; conditional E-value: 9.3 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ + +kAi+Y e+ l+ FUN_002333-T1 194 LGTAYQSLGDSRKAIEYHEKHLE 216 5777888888899****998776 PP == domain 5 score: 4.4 bits; conditional E-value: 0.082 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e++l++ + FUN_002333-T1 234 LGNAYQSLGDFRKAIEYHEKILEIAK 259 799*****************998765 PP == domain 6 score: 3.4 bits; conditional E-value: 0.17 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002333-T1 274 LGNAYQSLGDFQKAIEYHEKHLE 296 799***************99876 PP == domain 7 score: 5.1 bits; conditional E-value: 0.049 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ lk+ + FUN_002333-T1 314 LGNAYQSLGDFRKAIKYHEKHLKIAK 339 799*****************999876 PP == domain 8 score: -0.4 bits; conditional E-value: 2.5 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G a+ +++kAi+Y e+ l++ FUN_002333-T1 354 LGSAYRSLGDFRKAIEYQEKDLEIA 378 6889999999*******99877665 PP == domain 9 score: 0.5 bits; conditional E-value: 1.3 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+ + +++kAi+Y e+ l+ FUN_002333-T1 394 LGNVYQSLGDFRKAIEYHEKNLQ 416 57777788899*******99876 PP == domain 10 score: 0.8 bits; conditional E-value: 1.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaa 25 +G+a+ +++kAi+Y + FUN_002333-T1 434 LGNAYQSLGDFRKAIEYHAKH 454 799**************9775 PP == domain 11 score: -0.4 bits; conditional E-value: 2.4 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G a+ +++kAi+Y e+ l+ FUN_002333-T1 475 GIAYRSLGDFRKAIEYHEKDLQ 496 667777779********98776 PP == domain 12 score: 1.3 bits; conditional E-value: 0.74 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaal 26 +G+a+ +++kAi+Y e+ l FUN_002333-T1 514 LGNAYQSLGDFRKAIEYLEKGL 535 799**************99866 PP == domain 13 score: -0.4 bits; conditional E-value: 2.5 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G a+ +++kAi+Y e+ l+ FUN_002333-T1 555 GIAYRSLGDFRKAIEYHEKRLE 576 667777779********98765 PP == domain 14 score: -0.5 bits; conditional E-value: 2.7 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G a+ +++kAi+Y e+ l+ FUN_002333-T1 635 GIAFQSLGDFRKAIEYHEKGLQ 656 6666677789*******98776 PP >> Transferase Transferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.084 58 268 332 .. 84 147 .. 56 176 .. 0.83 2 ! 9.5 0.0 0.00071 0.49 268 330 .. 204 265 .. 197 281 .. 0.83 3 ? -1.3 0.0 1.3 9.2e+02 275 320 .. 291 336 .. 279 349 .. 0.81 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.084 Transferase 268 askldeeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivekvkeavkk 332 ++k+ e +e+ l ia+++ +r+ + + GNa++s +a e ++ l i+++v+ +v + FUN_002333-T1 84 SRKAIEYHEKRLEIAIEVGHRVGEGNAYGNLGNAYQSLGDSRKAIEYHEKHLE-IAKEVSDRVGE 147 66777778899****************************99999999999885.56666666665 PP == domain 2 score: 9.5 bits; conditional E-value: 0.00071 Transferase 268 askldeeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivekvkeav 330 ++k+ e +e+ l ia+++R+r+ + ++ GNa++s + +a e ++ + i+++v+ +v FUN_002333-T1 204 SRKAIEYHEKHLEIAIEVRHRVGEGNAYGSLGNAYQSLGDFRKAIEYHEK-ILEIAKEVSDKV 265 6677777889****************************999999987765.445666666555 PP == domain 3 score: -1.3 bits; conditional E-value: 1.3 Transferase 275 ketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseels 320 +e+ l ia+++ +r+ + + GNa++s + +a ++ l+ FUN_002333-T1 291 HEKHLEIAIEVGHRVGEGSAYGNLGNAYQSLGDFRKAIKYHEKHLK 336 558999***********************99988888777777765 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.0 0.19 1.3e+02 82 115 .. 57 89 .. 52 90 .. 0.85 2 ? 1.3 0.0 0.83 5.7e+02 90 115 .. 104 129 .. 93 130 .. 0.87 3 ? 3.5 0.0 0.17 1.2e+02 81 115 .. 138 169 .. 131 170 .. 0.84 4 ? -0.0 0.0 2 1.4e+03 90 115 .. 184 209 .. 173 210 .. 0.86 5 ? 3.4 0.0 0.18 1.2e+02 75 107 .. 216 248 .. 202 257 .. 0.84 6 ? -1.3 0.0 5.1 3.5e+03 75 106 .. 256 287 .. 247 290 .. 0.73 7 ? -1.2 0.0 4.9 3.4e+03 83 106 .. 304 327 .. 289 330 .. 0.64 8 ? 4.5 0.0 0.08 55 75 107 .. 336 368 .. 326 372 .. 0.87 9 ? 2.7 0.0 0.29 2e+02 75 107 .. 376 408 .. 367 410 .. 0.85 10 ? -2.0 0.0 8.3 5.7e+03 92 107 .. 433 448 .. 414 450 .. 0.69 11 ? -1.1 0.0 4.6 3.2e+03 82 107 .. 503 528 .. 476 537 .. 0.73 12 ? 1.9 0.0 0.54 3.7e+02 51 91 .. 1078 1118 .. 1072 1122 .. 0.75 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.19 GGDEF_2 82 rrlggitvriGvGrpveglaglrrSyreArrAlr 115 +++++ r+G G+++e+l ++++S + r+A++ FUN_002333-T1 57 KAIEA-GHRVGEGSAYENLGNAYQSLGDSRKAIE 89 55555.6799**********************97 PP == domain 2 score: 1.3 bits; conditional E-value: 0.83 GGDEF_2 90 riGvGrpveglaglrrSyreArrAlr 115 r+G G+++ +l ++++S + r+A++ FUN_002333-T1 104 RVGEGNAYGNLGNAYQSLGDSRKAIE 129 8999********************97 PP == domain 3 score: 3.5 bits; conditional E-value: 0.17 GGDEF_2 81 rrrlggitvriGvGrpveglaglrrSyreArrAlr 115 ++++++ r+G G+++e+l ++++S + r+A++ FUN_002333-T1 138 AKEVSD---RVGEGSAYENLGNAYQSLGDSRKAIE 169 455555...8999********************97 PP == domain 4 score: -0.0 bits; conditional E-value: 2 GGDEF_2 90 riGvGrpveglaglrrSyreArrAlr 115 r+G G+++ +l +++S + r+A++ FUN_002333-T1 184 RVGEGNAYGNLGTAYQSLGDSRKAIE 209 8999*******************997 PP == domain 5 score: 3.4 bits; conditional E-value: 0.18 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++r+r+g+ +++ +G+++++l ++r++ FUN_002333-T1 216 EIAIEVRHRVGEGNAYGSLGNAYQSLGDFRKAI 248 7888999999999*****************986 PP == domain 6 score: -1.3 bits; conditional E-value: 5.1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e+++++++ +g+ ++ +G+++++l ++ ++ FUN_002333-T1 256 EIAKEVSDKVGEGGAYGNLGNAYQSLGDFQKA 287 66777777777777777788888888888776 PP == domain 7 score: -1.2 bits; conditional E-value: 4.9 GGDEF_2 83 rlggitvriGvGrpveglaglrrS 106 r+g+ +++ +G+++++l ++r++ FUN_002333-T1 304 RVGEGSAYGNLGNAYQSLGDFRKA 327 444445555567777777777776 PP == domain 8 score: 4.5 bits; conditional E-value: 0.08 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 ++++++ +r+g+ +v+ +G+++++l ++r++ FUN_002333-T1 336 KIAKEVGDRVGEGNVYGSLGSAYRSLGDFRKAI 368 789999999999******************985 PP == domain 9 score: 2.7 bits; conditional E-value: 0.29 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ ++ +G+++++l ++r++ FUN_002333-T1 376 EIAKEVSDRVGEGGAYGNLGNVYQSLGDFRKAI 408 899999999999999999***********9985 PP == domain 10 score: -2.0 bits; conditional E-value: 8.3 GGDEF_2 92 GvGrpveglaglrrSy 107 +G+++++l ++r++ FUN_002333-T1 433 NLGNAYQSLGDFRKAI 448 4688888888888875 PP == domain 11 score: -1.1 bits; conditional E-value: 4.6 GGDEF_2 82 rrlggitvriGvGrpveglaglrrSy 107 +r g+ ++ +G+++++l ++r++ FUN_002333-T1 503 DRAGEGGAYGNLGNAYQSLGDFRKAI 528 45555555556788999999998876 PP == domain 12 score: 1.9 bits; conditional E-value: 0.54 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvri 91 +l+a ++ lv+l++ ddea ++e+++r+ ++l++ t+++ FUN_002333-T1 1078 AFLAAGARSVLVALWAIDDEA-TKEFMKRFYQHLKEgKTASA 1118 56777788899********86.57888888888887655555 PP >> Cdc6_lid Cdc6 AAA+ ATPase-type lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 4.1 2.8e+03 31 43 .. 79 91 .. 76 104 .. 0.75 2 ? 0.3 0.0 1.4 9.4e+02 31 53 .. 119 141 .. 116 149 .. 0.78 3 ? -1.2 0.0 4.1 2.8e+03 31 43 .. 159 171 .. 156 184 .. 0.75 4 ? -1.2 0.0 3.9 2.7e+03 30 42 .. 198 210 .. 196 222 .. 0.78 5 ? -0.4 0.0 2.2 1.5e+03 31 52 .. 239 260 .. 236 267 .. 0.73 6 ? -1.0 0.0 3.4 2.3e+03 31 55 .. 319 343 .. 316 351 .. 0.74 7 ? -0.7 0.0 2.9 2e+03 31 52 .. 359 380 .. 356 387 .. 0.75 8 ? -2.0 0.0 7 4.8e+03 32 45 .. 400 413 .. 398 424 .. 0.72 9 ? -2.2 0.0 8.2 5.7e+03 31 41 .. 439 449 .. 437 459 .. 0.83 10 ? -1.3 0.0 4.3 3e+03 29 42 .. 477 490 .. 475 504 .. 0.79 11 ? 5.4 0.0 0.035 24 31 55 .. 519 543 .. 516 547 .. 0.84 12 ? -0.8 0.0 3.1 2.1e+03 29 45 .. 557 573 .. 555 585 .. 0.73 13 ? 0.1 0.0 1.5 1.1e+03 28 50 .. 636 658 .. 635 665 .. 0.76 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 4.1 Cdc6_lid 31 qesGDaRrAldlL 43 q+ GD R+A++ FUN_002333-T1 79 QSLGDSRKAIEYH 91 678*******965 PP == domain 2 score: 0.3 bits; conditional E-value: 1.4 Cdc6_lid 31 qesGDaRrAldlLrkAgelAere 53 q+ GD R+A++ +k e+A++ FUN_002333-T1 119 QSLGDSRKAIEYHEKHLEIAKEV 141 678*******9988888887764 PP == domain 3 score: -1.2 bits; conditional E-value: 4.1 Cdc6_lid 31 qesGDaRrAldlL 43 q+ GD R+A++ FUN_002333-T1 159 QSLGDSRKAIEYH 171 678*******965 PP == domain 4 score: -1.2 bits; conditional E-value: 3.9 Cdc6_lid 30 aqesGDaRrAldl 42 q+ GD R+A++ FUN_002333-T1 198 YQSLGDSRKAIEY 210 5778*******86 PP == domain 5 score: -0.4 bits; conditional E-value: 2.2 Cdc6_lid 31 qesGDaRrAldlLrkAgelAer 52 q+ GD R+A++ +k e+A++ FUN_002333-T1 239 QSLGDFRKAIEYHEKILEIAKE 260 678*******976666666654 PP == domain 6 score: -1.0 bits; conditional E-value: 3.4 Cdc6_lid 31 qesGDaRrAldlLrkAgelAeregs 55 q+ GD R+A+ +k ++A++ g+ FUN_002333-T1 319 QSLGDFRKAIKYHEKHLKIAKEVGD 343 678*******987777777776664 PP == domain 7 score: -0.7 bits; conditional E-value: 2.9 Cdc6_lid 31 qesGDaRrAldlLrkAgelAer 52 ++ GD R+A++ +k e+A++ FUN_002333-T1 359 RSLGDFRKAIEYQEKDLEIAKE 380 567*******987777777765 PP == domain 8 score: -2.0 bits; conditional E-value: 7 Cdc6_lid 32 esGDaRrAldlLrk 45 + GD R+A++ +k FUN_002333-T1 400 SLGDFRKAIEYHEK 413 56*******97655 PP == domain 9 score: -2.2 bits; conditional E-value: 8.2 Cdc6_lid 31 qesGDaRrAld 41 q+ GD R+A++ FUN_002333-T1 439 QSLGDFRKAIE 449 678******98 PP == domain 10 score: -1.3 bits; conditional E-value: 4.3 Cdc6_lid 29 aaqesGDaRrAldl 42 a ++ GD R+A++ FUN_002333-T1 477 AYRSLGDFRKAIEY 490 66788*******85 PP == domain 11 score: 5.4 bits; conditional E-value: 0.035 Cdc6_lid 31 qesGDaRrAldlLrkAgelAeregs 55 q+ GD R+A++ L+k e+A + g+ FUN_002333-T1 519 QSLGDFRKAIEYLEKGLEIAIEVGD 543 778************9999977665 PP == domain 12 score: -0.8 bits; conditional E-value: 3.1 Cdc6_lid 29 aaqesGDaRrAldlLrk 45 a ++ GD R+A++ +k FUN_002333-T1 557 AYRSLGDFRKAIEYHEK 573 66788*******97655 PP == domain 13 score: 0.1 bits; conditional E-value: 1.5 Cdc6_lid 28 laaqesGDaRrAldlLrkAgelA 50 +a q+ GD R+A++ +k ++A FUN_002333-T1 636 IAFQSLGDFRKAIEYHEKGLQIA 658 577889*******9877766666 PP >> NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 3.6 2.5e+03 67 89 .. 286 306 .. 277 339 .. 0.83 2 ? 0.8 0.0 1.1 7.7e+02 70 89 .. 367 386 .. 361 394 .. 0.86 3 ? -0.8 0.0 3.4 2.4e+03 70 89 .. 407 426 .. 397 454 .. 0.87 4 ? -2.0 0.0 8 5.5e+03 70 89 .. 447 466 .. 436 474 .. 0.86 5 ? 4.6 0.0 0.076 52 70 89 .. 487 506 .. 479 520 .. 0.87 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 3.6 NAD_binding_11 67 pgFaidlllKDlglaldlarelg 89 + ai+++ K l++a+++++++g FUN_002333-T1 286 K--AIEYHEKHLEIAIEVGHRVG 306 3..799*************9987 PP == domain 2 score: 0.8 bits; conditional E-value: 1.1 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ KDl++a ++ +++g FUN_002333-T1 367 AIEYQEKDLEIAKEVSDRVG 386 7999*********9998876 PP == domain 3 score: -0.8 bits; conditional E-value: 3.4 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002333-T1 407 AIEYHEKNLQIAVEVGDRAG 426 799************99887 PP == domain 4 score: -2.0 bits; conditional E-value: 8 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai++++K l+la+++++++g FUN_002333-T1 447 AIEYHAKHLELAIAVGDRVG 466 799***********999886 PP == domain 5 score: 4.6 bits; conditional E-value: 0.076 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ KDl++a+++++++g FUN_002333-T1 487 AIEYHEKDLQIAIEVGDRAG 506 799************99987 PP >> CAMSAP_CC1 Spectrin-binding region of Ca2+-Calmodulin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.1 0.12 82 25 41 .. 83 99 .. 79 104 .. 0.86 2 ? 0.3 0.1 1.4 9.4e+02 25 39 .. 123 137 .. 120 140 .. 0.84 3 ? 3.7 0.1 0.12 82 25 41 .. 163 179 .. 159 184 .. 0.86 4 ? 3.0 0.1 0.2 1.3e+02 25 45 .. 203 224 .. 199 230 .. 0.80 5 ? 2.0 0.1 0.39 2.7e+02 27 39 .. 365 377 .. 361 380 .. 0.87 6 ? 0.1 0.0 1.6 1.1e+03 27 41 .. 445 459 .. 441 461 .. 0.87 7 ? 2.4 0.1 0.29 2e+02 27 40 .. 565 578 .. 561 580 .. 0.88 8 ? -0.9 0.0 3.1 2.2e+03 23 40 .. 601 618 .. 593 620 .. 0.78 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.12 CAMSAP_CC1 25 EKRraIEaqKrriEaaf 41 + R+aIE +r+E a+ FUN_002333-T1 83 DSRKAIEYHEKRLEIAI 99 67************775 PP == domain 2 score: 0.3 bits; conditional E-value: 1.4 CAMSAP_CC1 25 EKRraIEaqKrriEa 39 + R+aIE + +E FUN_002333-T1 123 DSRKAIEYHEKHLEI 137 67*******999996 PP == domain 3 score: 3.7 bits; conditional E-value: 0.12 CAMSAP_CC1 25 EKRraIEaqKrriEaaf 41 + R+aIE +r+E a+ FUN_002333-T1 163 DSRKAIEYHEKRLEIAI 179 67************775 PP == domain 4 score: 3.0 bits; conditional E-value: 0.2 CAMSAP_CC1 25 EKRraIEaqKrriEaafa.rqR 45 + R+aIE + +E a++ r+R FUN_002333-T1 203 DSRKAIEYHEKHLEIAIEvRHR 224 67************76643676 PP == domain 5 score: 2.0 bits; conditional E-value: 0.39 CAMSAP_CC1 27 RraIEaqKrriEa 39 R+aIE q + +E FUN_002333-T1 365 RKAIEYQEKDLEI 377 9********9996 PP == domain 6 score: 0.1 bits; conditional E-value: 1.6 CAMSAP_CC1 27 RraIEaqKrriEaaf 41 R+aIE + +E a+ FUN_002333-T1 445 RKAIEYHAKHLELAI 459 9**********9876 PP == domain 7 score: 2.4 bits; conditional E-value: 0.29 CAMSAP_CC1 27 RraIEaqKrriEaa 40 R+aIE +r+E a FUN_002333-T1 565 RKAIEYHEKRLEIA 578 9***********76 PP == domain 8 score: -0.9 bits; conditional E-value: 3.1 CAMSAP_CC1 23 LEEKRraIEaqKrriEaa 40 L + R+aIE + +E a FUN_002333-T1 601 LGDCRKAIEYHAKLLEIA 618 6677*****999988866 PP >> TPR_3 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.026 18 7 23 .. 34 50 .. 33 52 .. 0.91 2 ? 1.1 0.0 0.97 6.7e+02 6 23 .. 233 250 .. 233 253 .. 0.90 3 ? 3.9 0.2 0.13 91 8 23 .. 275 290 .. 273 293 .. 0.88 4 ? -2.0 0.1 9.1 6.3e+03 10 22 .. 317 329 .. 314 331 .. 0.84 5 ? -1.9 0.0 9 6.2e+03 7 24 .. 354 371 .. 353 372 .. 0.81 6 ? 0.3 0.0 1.8 1.2e+03 8 23 .. 395 410 .. 393 412 .. 0.88 7 ? 0.0 0.1 2.2 1.5e+03 8 23 .. 435 450 .. 433 452 .. 0.87 8 ? -0.2 0.0 2.6 1.8e+03 8 23 .. 515 530 .. 513 531 .. 0.87 9 ? 2.6 0.0 0.32 2.2e+02 6 23 .. 633 650 .. 633 652 .. 0.92 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.026 TPR_3 7 lAatfylkgkyqeArel 23 lA++f++ g++ eA+ + FUN_002333-T1 34 LAYVFQSLGNFREAIKY 50 8*************965 PP == domain 2 score: 1.1 bits; conditional E-value: 0.97 TPR_3 6 slAatfylkgkyqeArel 23 sl+ ++++ g++ +A+e+ FUN_002333-T1 233 SLGNAYQSLGDFRKAIEY 250 67889***********97 PP == domain 3 score: 3.9 bits; conditional E-value: 0.13 TPR_3 8 AatfylkgkyqeArel 23 + ++++ g++q+A+e+ FUN_002333-T1 275 GNAYQSLGDFQKAIEY 290 5589**********97 PP == domain 4 score: -2.0 bits; conditional E-value: 9.1 TPR_3 10 tfylkgkyqeAre 22 ++++ g++ +A+ FUN_002333-T1 317 AYQSLGDFRKAIK 329 89*********86 PP == domain 5 score: -1.9 bits; conditional E-value: 9 TPR_3 7 lAatfylkgkyqeArely 24 l+ ++ + g++ +A+e++ FUN_002333-T1 354 LGSAYRSLGDFRKAIEYQ 371 677777889*******98 PP == domain 6 score: 0.3 bits; conditional E-value: 1.8 TPR_3 8 AatfylkgkyqeArel 23 + ++++ g++ +A+e+ FUN_002333-T1 395 GNVYQSLGDFRKAIEY 410 568***********97 PP == domain 7 score: 0.0 bits; conditional E-value: 2.2 TPR_3 8 AatfylkgkyqeArel 23 + ++++ g++ +A+e+ FUN_002333-T1 435 GNAYQSLGDFRKAIEY 450 5589*********997 PP == domain 8 score: -0.2 bits; conditional E-value: 2.6 TPR_3 8 AatfylkgkyqeArel 23 + ++++ g++ +A+e+ FUN_002333-T1 515 GNAYQSLGDFRKAIEY 530 5589*********997 PP == domain 9 score: 2.6 bits; conditional E-value: 0.32 TPR_3 6 slAatfylkgkyqeArel 23 sl+ +f++ g++ +A+e+ FUN_002333-T1 633 SLGIAFQSLGDFRKAIEY 650 7899************97 PP >> PSMA-like_N Maltose-forming alpha-amylase-like, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 1.1 7.7e+02 18 69 .. 77 127 .. 69 140 .. 0.74 2 ? -0.3 0.0 0.97 6.7e+02 18 69 .. 157 207 .. 145 220 .. 0.73 3 ? 2.7 0.0 0.13 88 17 68 .. 196 246 .. 188 261 .. 0.77 4 ? -1.6 0.0 2.5 1.7e+03 17 52 .. 396 431 .. 389 452 .. 0.77 5 ? -0.4 0.0 1.1 7.6e+02 11 65 .. 470 523 .. 468 543 .. 0.75 6 ? -0.8 0.0 1.4 9.6e+02 11 49 .. 550 588 .. 547 594 .. 0.84 7 ? 3.3 0.0 0.083 57 11 52 .. 590 631 .. 586 661 .. 0.82 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 1.1 PSMA-like_N 18 vyvkdgdgkdpikyeerkspvalkireeevkgenwtramlkayeyvddvlkr 69 y gd ++ i+y+e++ +a+ + + g+ + + +ay+ + d k FUN_002333-T1 77 AYQSLGDSRKAIEYHEKRLEIAIEVGHRVGEGNAYG-NLGNAYQSLGDSRKA 127 57778999***************9988777776654.455666666666555 PP == domain 2 score: -0.3 bits; conditional E-value: 0.97 PSMA-like_N 18 vyvkdgdgkdpikyeerkspvalkireeevkgenwtramlkayeyvddvlkr 69 y gd ++ i+y+e++ +a+ + + g+ + + ay+ + d k FUN_002333-T1 157 AYQSLGDSRKAIEYHEKRLEIAIEVGHRVGEGNAYG-NLGTAYQSLGDSRKA 207 67778999999******9999999988777776654.455666666666555 PP == domain 3 score: 2.7 bits; conditional E-value: 0.13 PSMA-like_N 17 ivyvkdgdgkdpikyeerkspvalkireeevkgenwtramlkayeyvddvlk 68 y gd ++ i+y+e++ +a+ +r+ g+ + ++ +ay+ + d k FUN_002333-T1 196 TAYQSLGDSRKAIEYHEKHLEIAIEVRHRVGEGNAYG-SLGNAYQSLGDFRK 246 5677889********************9988887664.45666666666555 PP == domain 4 score: -1.6 bits; conditional E-value: 2.5 PSMA-like_N 17 ivyvkdgdgkdpikyeerkspvalkireeevkgenw 52 vy gd ++ i+y+e+ +a+ + + g + FUN_002333-T1 396 NVYQSLGDFRKAIEYHEKNLQIAVEVGDRAGEGGAY 431 5888999*****************999988777655 PP == domain 5 score: -0.4 bits; conditional E-value: 1.1 PSMA-like_N 11 ayqpgdivyvkdgdgkdpikyeerkspvalkireeevkgenwtramlkayeyvdd 65 ay i y gd ++ i+y+e+ +a+ + + g + + +ay+ + d FUN_002333-T1 470 AYGNLGIAYRSLGDFRKAIEYHEKDLQIAIEVGDRAGEGGAYGN-LGNAYQSLGD 523 566667899999*******************9999888876653.4455555555 PP == domain 6 score: -0.8 bits; conditional E-value: 1.4 PSMA-like_N 11 ayqpgdivyvkdgdgkdpikyeerkspvalkireeevkg 49 ay i y gd ++ i+y+e++ +a+ + + g FUN_002333-T1 550 AYGNLGIAYRSLGDFRKAIEYHEKRLEIAIEVGDRVGEG 588 677777999999******************998876555 PP == domain 7 score: 3.3 bits; conditional E-value: 0.083 PSMA-like_N 11 ayqpgdivyvkdgdgkdpikyeerkspvalkireeevkgenw 52 ay ivy+ gd ++ i+y+ ++ +a+ + + g + FUN_002333-T1 590 AYGNLGIVYLSLGDCRKAIEYHAKLLEIAIAVGDRVGEGSAY 631 777888************************999988777766 PP >> RNPP_C RNPP family C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.1 5.1 3.5e+03 85 153 .. 34 100 .. 31 105 .. 0.60 2 ? 5.2 0.1 0.027 19 84 154 .. 233 301 .. 206 333 .. 0.85 3 ? -2.7 0.0 7 4.8e+03 126 152 .. 393 419 .. 349 423 .. 0.52 4 ? -1.9 0.0 4 2.8e+03 135 154 .. 522 541 .. 510 551 .. 0.85 5 ? -1.5 0.0 3 2.1e+03 134 153 .. 641 660 .. 592 665 .. 0.64 6 ? 0.1 0.0 0.98 6.7e+02 85 153 .. 681 752 .. 652 757 .. 0.81 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 5.1 RNPP_C 85 lAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsie 153 lA+v+ g+++++i++++ l ++a e + + + n + d +++e+ ++ ++++ie FUN_002333-T1 34 LAYVFQSLGNFREAIKYHEIHL--EKAIEAGHRVGEGSAYENLGNAYQSLGDSRKAIEYHEKRLEIAIE 100 7888888899999996655334..334444434444444445555555556666666666666666665 PP == domain 2 score: 5.2 bits; conditional E-value: 0.027 RNPP_C 84 slAnvyAeegkinksielyqqvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsiek 154 sl n y g ++k+ie+++++l e a+e + ++ + n + d+++++e+ ++ ++++ie FUN_002333-T1 233 SLGNAYQSLGDFRKAIEYHEKIL-EI-AKEVSDKVGEGGAYGNLGNAYQSLGDFQKAIEYHEKHLEIAIEV 301 89999******************.44.4444413445555558888888899*************999985 PP == domain 3 score: -2.7 bits; conditional E-value: 7 RNPP_C 126 nysklLydkndydsslevinqaiklsi 152 n + + d+ +++e+ ++ +++++ FUN_002333-T1 393 NLGNVYQSLGDFRKAIEYHEKNLQIAV 419 444444444566666666666666555 PP == domain 4 score: -1.9 bits; conditional E-value: 4 RNPP_C 135 ndydsslevinqaiklsiek 154 d+ +++e+ +++++++ie FUN_002333-T1 522 GDFRKAIEYLEKGLEIAIEV 541 588999*********99985 PP == domain 5 score: -1.5 bits; conditional E-value: 3 RNPP_C 134 kndydsslevinqaiklsie 153 d+ +++e+ +++++++ie FUN_002333-T1 641 LGDFRKAIEYHEKGLQIAIE 660 36899999999999999998 PP == domain 6 score: 0.1 bits; conditional E-value: 0.98 RNPP_C 85 lAnvyAeegkinksielyq...qvldeseaqeedyeelkikvlYnysklLydkndydsslevinqaiklsie 153 l + +k++ +++++ + l+++ + + ++ el+ Y + L ++d++l +q+ ++++ FUN_002333-T1 681 LGQFENALDKFDSAVKVFDtlrSFLKSEDDWKINFRELHENSYYAIWRSLLRIGKIDEALFAADQGRAQTLS 752 55555556778888888876668888888888999******************************9888876 PP >> Urocanase_N Urocanase N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 2.4 1.7e+03 40 64 .. 230 254 .. 216 264 .. 0.84 2 ? 0.5 0.0 1.1 7.3e+02 30 62 .. 260 292 .. 252 307 .. 0.77 3 ? -0.4 0.0 2 1.4e+03 30 61 .. 300 331 .. 278 336 .. 0.83 4 ? 1.3 0.0 0.56 3.9e+02 30 61 .. 340 371 .. 334 377 .. 0.82 5 ? -0.2 0.0 1.7 1.2e+03 30 61 .. 380 411 .. 370 421 .. 0.77 6 ? -0.6 0.0 2.3 1.6e+03 30 61 .. 420 451 .. 412 466 .. 0.80 7 ? -2.2 0.0 6.9 4.8e+03 35 61 .. 465 491 .. 452 500 .. 0.80 8 ? 1.7 0.0 0.43 3e+02 38 63 .. 508 533 .. 495 536 .. 0.83 9 ? -2.5 0.0 9 6.2e+03 36 60 .. 546 570 .. 526 574 .. 0.80 10 ? -2.4 0.0 8 5.5e+03 40 60 .. 630 650 .. 617 653 .. 0.83 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 2.4 Urocanase_N 40 vYGgtGkaarnweqfelivktLkel 64 YG G+a ++ f++ +++ +++ FUN_002333-T1 230 AYGSLGNAYQSLGDFRKAIEYHEKI 254 7***************999987765 PP == domain 2 score: 0.5 bits; conditional E-value: 1.1 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivktLk 62 ev++k e YG+ G+a ++ f++ +++ + FUN_002333-T1 260 EVSDKVGEGGAYGNLGNAYQSLGDFQKAIEYHE 292 56666666668***************9998864 PP == domain 3 score: -0.4 bits; conditional E-value: 2 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivktL 61 ev ++ e YG+ G+a ++ f++ +k+ FUN_002333-T1 300 EVGHRVGEGSAYGNLGNAYQSLGDFRKAIKYH 331 55566666678**************9999875 PP == domain 4 score: 1.3 bits; conditional E-value: 0.56 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivktL 61 ev ++ e vYG G+a r+ f++ +++ FUN_002333-T1 340 EVGDRVGEGNVYGSLGSAYRSLGDFRKAIEYQ 371 66666777779**************9998875 PP == domain 5 score: -0.2 bits; conditional E-value: 1.7 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivktL 61 ev+++ e YG+ G++ ++ f++ +++ FUN_002333-T1 380 EVSDRVGEGGAYGNLGNVYQSLGDFRKAIEYH 411 44444555558**************9998875 PP == domain 6 score: -0.6 bits; conditional E-value: 2.3 Urocanase_N 30 evaekpeeLvvYGgtGkaarnweqfelivktL 61 ev ++ e YG+ G+a ++ f++ +++ FUN_002333-T1 420 EVGDRAGEGGAYGNLGNAYQSLGDFRKAIEYH 451 55566666668**************9998875 PP == domain 7 score: -2.2 bits; conditional E-value: 6.9 Urocanase_N 35 peeLvvYGgtGkaarnweqfelivktL 61 e YG+ G a r+ f++ +++ FUN_002333-T1 465 VGEGSAYGNLGIAYRSLGDFRKAIEYH 491 555668************999998875 PP == domain 8 score: 1.7 bits; conditional E-value: 0.43 Urocanase_N 38 LvvYGgtGkaarnweqfelivktLke 63 YG+ G+a ++ f++ +++L++ FUN_002333-T1 508 GGAYGNLGNAYQSLGDFRKAIEYLEK 533 557********************985 PP == domain 9 score: -2.5 bits; conditional E-value: 9 Urocanase_N 36 eeLvvYGgtGkaarnweqfelivkt 60 e YG+ G a r+ f++ +++ FUN_002333-T1 546 GEGRAYGNLGIAYRSLGDFRKAIEY 570 55557**********9999998887 PP == domain 10 score: -2.4 bits; conditional E-value: 8 Urocanase_N 40 vYGgtGkaarnweqfelivkt 60 YG G a+++ f++ +++ FUN_002333-T1 630 AYGSLGIAFQSLGDFRKAIEY 650 7*************9998887 PP >> Mre11_C_bact Mre11 C-terminal domain, bacteria # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.1 0.0 0.0053 3.7 20 39 .. 5 24 .. 3 26 .. 0.88 2 ? -2.3 0.1 9.2 6.4e+03 23 35 .. 86 98 .. 85 105 .. 0.77 3 ? 2.4 0.0 0.31 2.2e+02 23 42 .. 126 145 .. 124 150 .. 0.84 4 ? -2.3 0.1 9.2 6.4e+03 23 35 .. 166 178 .. 165 185 .. 0.77 5 ? -1.9 0.1 7.3 5e+03 23 37 .. 206 220 .. 205 226 .. 0.78 6 ? 5.1 0.0 0.047 32 22 42 .. 245 265 .. 243 270 .. 0.86 7 ? -1.8 0.1 6.8 4.7e+03 23 35 .. 286 298 .. 284 305 .. 0.79 8 ? 2.9 0.0 0.22 1.5e+02 26 42 .. 329 345 .. 324 349 .. 0.83 9 ? -0.5 0.0 2.6 1.8e+03 22 38 .. 405 421 .. 403 425 .. 0.80 10 ? -1.3 0.0 4.7 3.3e+03 23 38 .. 486 501 .. 484 505 .. 0.78 11 ? 0.1 0.0 1.6 1.1e+03 22 42 .. 565 585 .. 563 588 .. 0.82 12 ? -2.2 0.0 8.6 5.9e+03 23 34 .. 606 617 .. 604 625 .. 0.81 13 ? -1.2 0.0 4.2 2.9e+03 23 38 .. 646 661 .. 644 668 .. 0.80 Alignments for each domain: == domain 1 score: 8.1 bits; conditional E-value: 0.0053 Mre11_C_bact 20 YLkkReenhekLLkiLDeLL 39 YL+k e hek Lki e+ FUN_002333-T1 5 YLRKAIECHEKHLKITMEIG 24 9**************88875 PP == domain 2 score: -2.3 bits; conditional E-value: 9.2 Mre11_C_bact 23 kReenhekLLkiL 35 k e hek L i FUN_002333-T1 86 KAIEYHEKRLEIA 98 55689***99986 PP == domain 3 score: 2.4 bits; conditional E-value: 0.31 Mre11_C_bact 23 kReenhekLLkiLDeLLDev 42 k e hek L i e+ D v FUN_002333-T1 126 KAIEYHEKHLEIAKEVSDRV 145 66699**********99988 PP == domain 4 score: -2.3 bits; conditional E-value: 9.2 Mre11_C_bact 23 kReenhekLLkiL 35 k e hek L i FUN_002333-T1 166 KAIEYHEKRLEIA 178 55689***99986 PP == domain 5 score: -1.9 bits; conditional E-value: 7.3 Mre11_C_bact 23 kReenhekLLkiLDe 37 k e hek L i e FUN_002333-T1 206 KAIEYHEKHLEIAIE 220 55699****999655 PP == domain 6 score: 5.1 bits; conditional E-value: 0.047 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek+L i e+ D v FUN_002333-T1 245 RKAIEYHEKILEIAKEVSDKV 265 577799***********9998 PP == domain 7 score: -1.8 bits; conditional E-value: 6.8 Mre11_C_bact 23 kReenhekLLkiL 35 k e hek L i FUN_002333-T1 286 KAIEYHEKHLEIA 298 66799****9996 PP == domain 8 score: 2.9 bits; conditional E-value: 0.22 Mre11_C_bact 26 enhekLLkiLDeLLDev 42 hek Lki e+ D v FUN_002333-T1 329 KYHEKHLKIAKEVGDRV 345 57**********99987 PP == domain 9 score: -0.5 bits; conditional E-value: 2.6 Mre11_C_bact 22 kkReenhekLLkiLDeL 38 +k e hek L+i e+ FUN_002333-T1 405 RKAIEYHEKNLQIAVEV 421 567799******98776 PP == domain 10 score: -1.3 bits; conditional E-value: 4.7 Mre11_C_bact 23 kReenhekLLkiLDeL 38 k e hek L+i e+ FUN_002333-T1 486 KAIEYHEKDLQIAIEV 501 67799*****997665 PP == domain 11 score: 0.1 bits; conditional E-value: 1.6 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002333-T1 565 RKAIEYHEKRLEIAIEVGDRV 585 567799*******98888776 PP == domain 12 score: -2.2 bits; conditional E-value: 8.6 Mre11_C_bact 23 kReenhekLLki 34 k e h kLL i FUN_002333-T1 606 KAIEYHAKLLEI 617 66799*****98 PP == domain 13 score: -1.2 bits; conditional E-value: 4.2 Mre11_C_bact 23 kReenhekLLkiLDeL 38 k e hek L+i e+ FUN_002333-T1 646 KAIEYHEKGLQIAIEV 661 67799*****997776 PP >> DUF2118 Uncharacterized protein conserved in archaea (DUF2118) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 1.6 1.1e+03 78 108 .. 82 112 .. 77 116 .. 0.82 2 ? 1.1 0.0 0.68 4.7e+02 78 112 .. 162 196 .. 156 201 .. 0.82 3 ? -0.4 0.0 2 1.4e+03 90 108 .. 294 312 .. 280 317 .. 0.77 4 ? 0.5 0.0 1 7.1e+02 90 109 .. 334 353 .. 318 361 .. 0.77 5 ? -2.1 0.0 6.6 4.5e+03 82 108 .. 406 432 .. 396 435 .. 0.77 6 ? 0.3 0.0 1.2 8.6e+02 92 108 .. 456 472 .. 441 477 .. 0.79 7 ? -1.5 0.0 4.3 3e+03 94 108 .. 538 552 .. 531 557 .. 0.84 8 ? -0.8 0.0 2.7 1.8e+03 85 108 .. 569 592 .. 560 595 .. 0.75 9 ? 2.8 0.0 0.21 1.5e+02 72 109 .. 596 633 .. 590 660 .. 0.86 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.6 DUF2118 78 GsklklvpvegvkvtlivkeGdrveegdtla 108 G+ k ++ + + ++G rv eg++++ FUN_002333-T1 82 GDSRKAIEYHEKRLEIAIEVGHRVGEGNAYG 112 6666777777788889999********9987 PP == domain 2 score: 1.1 bits; conditional E-value: 0.68 DUF2118 78 GsklklvpvegvkvtlivkeGdrveegdtlaavlt 112 G+ k ++ + + ++G rv eg++++ + t FUN_002333-T1 162 GDSRKAIEYHEKRLEIAIEVGHRVGEGNAYGNLGT 196 666677777788888999***********997765 PP == domain 3 score: -0.4 bits; conditional E-value: 2 DUF2118 90 kvtlivkeGdrveegdtla 108 + + ++G rv eg++++ FUN_002333-T1 294 HLEIAIEVGHRVGEGSAYG 312 5567789*********997 PP == domain 4 score: 0.5 bits; conditional E-value: 1 DUF2118 90 kvtlivkeGdrveegdtlaa 109 + + ++Gdrv eg++++ FUN_002333-T1 334 HLKIAKEVGDRVGEGNVYGS 353 45566789********9986 PP == domain 5 score: -2.1 bits; conditional E-value: 6.6 DUF2118 82 klvpvegvkvtlivkeGdrveegdtla 108 k ++ + ++ v++Gdr eg +++ FUN_002333-T1 406 KAIEYHEKNLQIAVEVGDRAGEGGAYG 432 55666666778999********99886 PP == domain 6 score: 0.3 bits; conditional E-value: 1.2 DUF2118 92 tlivkeGdrveegdtla 108 l +Gdrv eg++++ FUN_002333-T1 456 ELAIAVGDRVGEGSAYG 472 556789********997 PP == domain 7 score: -1.5 bits; conditional E-value: 4.3 DUF2118 94 ivkeGdrveegdtla 108 ++Gdrv eg +++ FUN_002333-T1 538 AIEVGDRVGEGRAYG 552 5689*******9987 PP == domain 8 score: -0.8 bits; conditional E-value: 2.7 DUF2118 85 pvegvkvtlivkeGdrveegdtla 108 + + + ++Gdrv eg +++ FUN_002333-T1 569 EYHEKRLEIAIEVGDRVGEGYAYG 592 5555566788899******98876 PP == domain 9 score: 2.8 bits; conditional E-value: 0.21 DUF2118 72 aillkkGsklklvpvegvkvtlivkeGdrveegdtlaa 109 +++l G+ k ++ + +Gdrv eg++++ FUN_002333-T1 596 IVYLSLGDCRKAIEYHAKLLEIAIAVGDRVGEGSAYGS 633 5788888888888888888889999*********9975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1161 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 538 (0.0210609); expected 510.9 (0.02) Passed bias filter: 479 (0.0187512); expected 510.9 (0.02) Passed Vit filter: 60 (0.0023488); expected 25.5 (0.001) Passed Fwd filter: 40 (0.00156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 37 [number of targets reported over threshold] # CPU time: 0.57u 0.37s 00:00:00.94 Elapsed: 00:00:00.46 # Mc/sec: 10087.76 // Query: FUN_002334-T1 [L=268] Description: FUN_002334 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-37 127.0 0.1 1.6e-17 64.3 0.1 2.1 2 Proteasome Proteasome subunit 9.3e-06 25.4 1.3 1.9e-05 24.5 1.3 1.5 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.3 0.1 1.2e-21 1.6e-17 14 102 .. 37 121 .. 35 138 .. 0.82 2 ! 60.8 0.0 1.5e-20 1.9e-16 105 189 .] 154 236 .. 143 236 .. 0.94 Alignments for each domain: == domain 1 score: 64.3 bits; conditional E-value: 1.2e-21 Proteasome 14 dgvvlaadkratagskllskdtveKifkiddhigvafaGlaaDartlvdyaraeaqlyrlrygepisvelvkrvaaklqaytqrsgrrp 102 dgv+l+ad+rat+ ++ ++++++Ki+ i ++i+++ aG+aaD++++++++++++ql++l++g + ++ + ++l + + r+ + FUN_002334-T1 37 DGVILGADTRATEDTIV-ADKNCSKIHYIAPNIYCCGAGTAADTEYVTQLISSNIQLHSLSTGCQAKMV---TALRMLKQRLFRYSFFA 121 9***********76666.6666******************************************99999...45555555555554444 PP == domain 2 score: 60.8 bits; conditional E-value: 1.5e-20 Proteasome 105 vslliagvdeegkprLyqidpsGsvieykdavaiGsgsqaaygvlekeykedltleeavelakkalkealerdklsgknievavi 189 ++ +++gv+ +g p L ++ p+Gs+ + ++v +G+gs aa++v+e+++k+d++l+ea++l+++++ + + +d+ sg+ni++++i FUN_002334-T1 154 AAHVLGGVNLNG-PTLHTVYPHGSTDKL-PYVTMGYGSLAAMSVFESRCKPDMELDEAKKLVRDTIAAGIFNDQGSGSNIDLCII 236 556789999666.***************.8*****************************************************97 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 1.3 1.5e-09 1.9e-05 1 18 [. 250 267 .. 250 268 .] 0.96 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.5e-09 Pr_beta_C 1 PNergeRqgsYkfkrGTT 18 +N +g Rqg+Y +krGTT FUN_002334-T1 250 ANDKGVRQGRYSYKRGTT 267 8***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (268 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 679 (0.0265805); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.34s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 2607.39 // Query: FUN_002335-T1 [L=1131] Description: FUN_002335 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-134 439.0 55.3 9.8e-18 64.6 0.6 10.0 11 TPR_12 Tetratricopeptide repeat 4.4e-123 391.5 40.4 7.1e-08 32.4 0.0 16.6 16 TPR_7 Tetratricopeptide repeat 2.6e-112 363.0 98.3 1.6e-07 31.3 0.7 17.8 17 TPR_1 Tetratricopeptide repeat 2.8e-76 250.0 34.8 0.0001 22.7 0.0 17.3 17 TPR_10 Tetratricopeptide repeat 1.6e-73 237.1 78.5 0.0002 21.7 0.5 17.4 17 TPR_8 Tetratricopeptide repeat 9.9e-49 166.8 0.0 1.5e-48 166.2 0.0 1.2 1 CHAT CHAT domain 3.5e-46 152.0 88.2 0.001 19.5 0.3 17.7 17 TPR_2 Tetratricopeptide repeat 3e-31 105.2 29.4 4.6 8.7 0.0 16.8 16 TPR_14 Tetratricopeptide repeat 3.3e-31 107.7 31.5 0.073 13.6 0.0 15.2 15 Rapsyn_N Rapsyn N-terminal myristoylation and linker 1.1e-20 74.7 0.1 9.8e-05 22.3 0.0 5.9 6 TPR_MalT MalT-like TPR region 1.8e-19 68.8 42.4 3.8 8.5 0.1 16.4 16 TPR_17 Tetratricopeptide repeat 4.4e-19 68.9 0.0 16 5.8 0.0 12.4 13 BAG6 BCL2-associated athanogene 6 1.6e-17 63.4 21.6 5.9 8.3 0.1 16.0 15 TPR_6 Tetratricopeptide repeat 2e-17 63.6 0.7 2.7 8.7 0.0 10.6 13 WH_Halo_primase Halobacteria primase winged helix domain 6.3e-15 54.8 32.6 12 6.9 0.0 15.8 15 PPR PPR repeat 8.9e-12 45.7 34.6 0.041 14.8 0.0 13.9 12 TPR_16 Tetratricopeptide repeat 2.6e-11 43.9 0.0 4.7e+02 1.5 0.0 13.6 15 DUF2977 Protein of unknown function (DUF2977) 2.8e-11 43.9 17.2 63 3.4 0.0 14.2 15 TPR_15 Tetratricopeptide repeat 2.4e-10 41.2 18.6 60 4.4 0.0 12.9 13 GGDEF_2 GGDEF-like domain 5.7e-10 40.1 24.9 86 3.8 0.0 14.0 14 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth A 2.5e-09 37.4 4.0 4.3 7.1 0.1 7.9 11 TPR_NPHP3 Nephrocystin-3 TPR domain 7.1e-09 36.0 28.3 33 5.1 0.0 13.2 13 Mre11_C_bact Mre11 C-terminal domain, bacteria 9.4e-08 31.6 7.0 0.13 11.3 0.1 7.2 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.2e-07 32.1 22.9 45 4.7 0.0 13.6 16 TPR_9 Tetratricopeptide repeat 6.3e-07 30.1 22.1 98 3.7 0.0 13.2 14 DUF7018 Domain of unknown function (DUF7018) 7.9e-07 29.8 17.4 20 6.1 0.1 9.9 12 TPR_19 Tetratricopeptide repeat 1.6e-06 28.5 6.0 4.4 7.4 0.0 9.7 12 Foie-gras_1 Foie gras liver health family 1 1.7e-06 28.0 0.0 87 2.5 0.0 8.7 12 Sec1 Sec1 family 2.3e-05 24.2 6.0 2 8.1 0.3 6.8 8 DUF6944 Family of unknown function (DUF6944) 2.6e-05 24.6 0.0 2.5e+02 2.3 0.0 9.4 14 CODH_A_N Carbon monoxide dehydrogenase subunit alpha 0.00068 19.9 32.4 21 5.2 0.2 13.4 14 RPN7 26S proteasome subunit RPN7 0.0023 18.7 20.9 4.1e+02 1.9 0.0 11.7 13 CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA recept ------ inclusion threshold ------ 0.46 10.8 21.8 30 4.9 0.1 7.6 8 ARM_TT21_C Tetratricopeptide repeat protein 21 C-termi 2.3 8.5 70.3 14 5.9 0.1 16.2 17 TPR_11 TPR repeat Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.7 0.5 1e-14 7.8e-12 7 75 .. 14 80 .. 8 82 .. 0.94 2 ! 57.0 0.3 3e-18 2.3e-15 4 77 .] 51 122 .. 48 122 .. 0.96 3 ! 60.9 0.9 1.8e-19 1.4e-16 4 77 .] 91 162 .. 88 162 .. 0.97 4 ! 64.6 0.6 1.3e-20 9.8e-18 5 77 .] 132 202 .. 129 202 .. 0.97 5 ! 36.4 0.2 8.3e-12 6.3e-09 4 57 .. 171 222 .. 168 223 .. 0.95 6 ! 29.4 0.1 1.3e-09 9.7e-07 22 76 .. 215 267 .. 206 268 .. 0.90 7 ! 60.5 0.3 2.5e-19 1.9e-16 5 77 .] 278 348 .. 274 348 .. 0.96 8 ! 59.5 0.4 5.1e-19 3.9e-16 4 77 .] 357 428 .. 354 428 .. 0.96 9 ! 55.6 0.3 8.2e-18 6.2e-15 4 77 .] 437 508 .. 434 508 .. 0.97 10 ! 52.2 0.2 9.8e-17 7.4e-14 5 75 .. 518 586 .. 514 588 .. 0.96 11 ! 41.2 0.1 2.6e-13 1.9e-10 4 68 .. 597 659 .. 594 668 .. 0.91 Alignments for each domain: == domain 1 score: 45.7 bits; conditional E-value: 1e-14 TPR_12 7 nnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 nlA + + lg++ +A++++ek l +a ++ +++ ++ +a+ Lg +y+ lgd+++A+++ e+ l+ia FUN_002335-T1 14 QNLAYAFQSLGDFRKAIKYHEKHLKIAIEA--GHRVGEGNAYGSLGNAYQSLGDFRKAIDYCEKYLKIA 80 49*************************999..99********************************998 PP == domain 2 score: 57.0 bits; conditional E-value: 3e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+++++ lg++ +A++++ek l +a ++ +++ ++ +a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002335-T1 51 NAYGSLGNAYQSLGDFRKAIDYCEKYLKIAIEV--GHRVGEGNAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 122 78989****************************..99**********************************986 PP == domain 3 score: 60.9 bits; conditional E-value: 1.8e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+++++ lg++ +A+e++ek le+a+++ d+ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002335-T1 91 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGGAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 162 799******************************..99**********************************986 PP == domain 4 score: 64.6 bits; conditional E-value: 1.3e-20 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+++++ lg++ +A+e++ek le+a+++ d+ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 202 799*****************************..9***********************************986 PP == domain 5 score: 36.4 bits; conditional E-value: 8.3e-12 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlyla 57 +a+ nl+++++ lg++ +A+e++ek le+a+++ d+ ++ +a+ Lg +y+ FUN_002335-T1 171 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGNAYGSLGNAYQS 222 7999*****************************..9***************975 PP == domain 6 score: 29.4 bits; conditional E-value: 1.3e-09 TPR_12 22 AlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +l + ++le+a+++ d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia+ FUN_002335-T1 215 SLGNAYQSLEIAKEV--CDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAN 267 6667789********..99**********************************97 PP == domain 7 score: 60.5 bits; conditional E-value: 2.5e-19 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ l+++++ lg++ +A+e++ek le+a+++ d+ ++ +a+ Lg +y+ lgd+++A+e++e+ leia++ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 348 6778****************************..9***********************************986 PP == domain 8 score: 59.5 bits; conditional E-value: 5.1e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ +++++ lg++ +A+e++ek le+a+++ d+ ++ +a+ Lg +y+ lgd+++A+e++e+ leia++ FUN_002335-T1 357 NAYGSRGNAYQSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 428 688889***************************..9***********************************986 PP == domain 9 score: 55.6 bits; conditional E-value: 8.2e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l++++r lg++ +A+e++ek le+a+++ d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia++ FUN_002335-T1 437 NAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 508 78989****************************..9***********************************986 PP == domain 10 score: 52.2 bits; conditional E-value: 9.8e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ l+++++ lg++ +A+e++ek le+a+++ d+ ++ a+ Lg +y+ lgd+++A+e++e+ l+ia FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKYLKIA 586 6778****************************..9**********************************98 PP == domain 11 score: 41.2 bits; conditional E-value: 2.6e-13 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlell 68 +a+ l+ ++ lg+ ++A+el+ek le+a+++ +d+ ++ +a++n+g y+ lg++e Al+ + FUN_002335-T1 597 NAYGSLGIAYSLLGDVQKAIELYEKHLEIAKEV--GDRKGEGIAYHNMGGEYFSLGQFENALDKF 659 78988****************************..78889**********************977 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 4.8e-07 0.00036 2 35 .. 13 46 .. 12 47 .. 0.90 2 ! 18.4 0.0 3.1e-06 0.0023 1 34 [. 52 85 .. 52 87 .. 0.86 3 ! 29.2 0.0 1e-09 7.7e-07 1 31 [. 92 122 .. 92 126 .. 0.94 4 ! 32.4 0.0 9.4e-11 7.1e-08 1 35 [. 132 166 .. 132 167 .. 0.96 5 ! 29.2 0.0 1e-09 7.7e-07 1 31 [. 172 202 .. 172 206 .. 0.94 6 ? -1.7 0.1 8.2 6.2e+03 1 12 [. 212 223 .. 212 224 .. 0.84 7 ! 29.4 0.0 9.2e-10 6.9e-07 1 35 [. 238 272 .. 238 273 .. 0.95 8 ! 27.5 0.0 3.6e-09 2.7e-06 1 31 [. 278 308 .. 278 312 .. 0.93 9 ! 29.0 0.1 1.2e-09 9.2e-07 1 31 [. 318 348 .. 318 352 .. 0.93 10 ! 21.5 0.1 3.1e-07 0.00023 6 31 .. 363 388 .. 358 392 .. 0.91 11 ! 29.0 0.1 1.2e-09 9.2e-07 1 31 [. 398 428 .. 398 432 .. 0.93 12 ! 32.2 0.0 1.1e-10 8.5e-08 1 35 [. 438 472 .. 438 473 .. 0.95 13 ! 27.5 0.0 3.6e-09 2.7e-06 1 31 [. 478 508 .. 478 512 .. 0.93 14 ! 30.7 0.0 3.3e-10 2.5e-07 1 35 [. 518 552 .. 518 553 .. 0.95 15 ! 21.5 0.0 3.1e-07 0.00023 1 35 [. 558 592 .. 558 593 .. 0.90 16 ! 28.7 0.1 1.5e-09 1.1e-06 1 35 [. 598 632 .. 598 633 .. 0.96 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 4.8e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 + +La ++++lGd+++Ai+++e++L +a + ++r FUN_002335-T1 13 YQNLAYAFQSLGDFRKAIKYHEKHLKIAIEAGHR 46 78***********************999877776 PP == domain 2 score: 18.4 bits; conditional E-value: 3.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L+++y++lGd+++Ai+++e+ L +a + ++ FUN_002335-T1 52 AYGSLGNAYQSLGDFRKAIDYCEKYLKIAIEVGH 85 7899*******************97777766665 PP == domain 3 score: 29.2 bits; conditional E-value: 1e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+++L+++y++lGd+++Ai+++e++L++ak+ FUN_002335-T1 92 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 122 789*************************997 PP == domain 4 score: 32.4 bits; conditional E-value: 9.4e-11 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 166 789****************************9998 PP == domain 5 score: 29.2 bits; conditional E-value: 1e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+++L+++y++lGd+++Ai+++e++L++ak+ FUN_002335-T1 172 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 202 789*************************997 PP == domain 6 score: -1.7 bits; conditional E-value: 8.2 TPR_7 1 aLsaLariyrkl 12 a+++L+++y++l FUN_002335-T1 212 AYGSLGNAYQSL 223 6889*****975 PP == domain 7 score: 29.4 bits; conditional E-value: 9.2e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a++ +dr FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHEKHLEIANEVSDR 272 7899**************************99997 PP == domain 8 score: 27.5 bits; conditional E-value: 3.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+++L+++y++lGd+++Ai+++e++L++ak+ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 308 7899************************997 PP == domain 9 score: 29.0 bits; conditional E-value: 1.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+++L+++yr+lGd+++Ai+++e++L++ak+ FUN_002335-T1 318 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 348 7899************************997 PP == domain 10 score: 21.5 bits; conditional E-value: 3.1e-07 TPR_7 6 ariyrklGdydeAirlyerlLalakd 31 +++y++lGd+++Ai+++e++L++ak+ FUN_002335-T1 363 GNAYQSLGDFRKAIEYHEKHLEIAKE 388 89*********************997 PP == domain 11 score: 29.0 bits; conditional E-value: 1.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+++L+++yr+lGd+++Ai+++e++L++ak+ FUN_002335-T1 398 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 428 7899************************997 PP == domain 12 score: 32.2 bits; conditional E-value: 1.1e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++ak+ +dr FUN_002335-T1 438 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVSDR 472 7899***************************9998 PP == domain 13 score: 27.5 bits; conditional E-value: 3.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakd 31 a+++L+++y++lGd+++Ai+++e++L++ak+ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 508 7899************************997 PP == domain 14 score: 30.7 bits; conditional E-value: 3.3e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 552 7899***************************9998 PP == domain 15 score: 21.5 bits; conditional E-value: 3.1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L +a + +dr FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIEYHEKYLKIAIEVGDR 592 7899********************88888888776 PP == domain 16 score: 28.7 bits; conditional E-value: 1.5e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y+ lGd ++Ai+lye++L++ak+ +dr FUN_002335-T1 598 AYGSLGIAYSLLGDVQKAIELYEKHLEIAKEVGDR 632 7899*****************************98 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.9 5.1e-07 0.00038 2 30 .. 11 39 .. 10 40 .. 0.94 2 ! 28.6 1.0 1.5e-09 1.2e-06 2 30 .. 51 79 .. 50 80 .. 0.95 3 ! 31.3 0.7 2.1e-10 1.6e-07 2 31 .. 91 120 .. 90 122 .. 0.94 4 ! 30.4 0.6 4.2e-10 3.2e-07 3 31 .. 132 160 .. 131 162 .. 0.95 5 ! 31.2 0.4 2.3e-10 1.7e-07 3 31 .. 172 200 .. 170 202 .. 0.94 6 ? 2.6 0.2 0.25 1.8e+02 2 14 .. 211 223 .. 210 224 .. 0.86 7 ! 26.8 0.3 5.8e-09 4.3e-06 3 30 .. 238 265 .. 237 268 .. 0.95 8 ! 27.2 0.3 4.4e-09 3.3e-06 3 31 .. 278 306 .. 277 308 .. 0.95 9 ! 28.2 0.3 2.1e-09 1.6e-06 2 31 .. 317 346 .. 316 348 .. 0.94 10 ! 27.9 0.3 2.6e-09 2e-06 2 31 .. 357 386 .. 356 388 .. 0.94 11 ! 28.2 0.3 2.1e-09 1.6e-06 2 31 .. 397 426 .. 396 428 .. 0.94 12 ! 28.2 0.3 2.1e-09 1.6e-06 2 31 .. 437 466 .. 436 468 .. 0.94 13 ! 27.2 0.3 4.4e-09 3.3e-06 3 31 .. 478 506 .. 477 508 .. 0.95 14 ! 27.2 0.3 4.4e-09 3.3e-06 3 31 .. 518 546 .. 517 548 .. 0.95 15 ! 24.6 0.8 2.9e-08 2.2e-05 3 30 .. 558 585 .. 557 586 .. 0.95 16 ! 24.6 0.3 2.8e-08 2.1e-05 2 31 .. 597 626 .. 596 628 .. 0.94 17 ! 12.8 0.1 0.00015 0.11 3 22 .. 638 657 .. 636 664 .. 0.88 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 5.1e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k++ nl++a+++lg++ +A++y ek L++ FUN_002335-T1 11 KSYQNLAYAFQSLGDFRKAIKYHEKHLKI 39 6799***********************98 PP == domain 2 score: 28.6 bits; conditional E-value: 1.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A++y+ek L++ FUN_002335-T1 51 NAYGSLGNAYQSLGDFRKAIDYCEKYLKI 79 59***********************9998 PP == domain 3 score: 31.3 bits; conditional E-value: 2.1e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002335-T1 91 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIA 120 69**************************96 PP == domain 4 score: 30.4 bits; conditional E-value: 4.2e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 160 8**************************96 PP == domain 5 score: 31.2 bits; conditional E-value: 2.3e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002335-T1 172 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 200 9**************************96 PP == domain 6 score: 2.6 bits; conditional E-value: 0.25 TPR_1 2 kalynlGnayfkl 14 +a+ lGnay++l FUN_002335-T1 211 NAYGSLGNAYQSL 223 5999******987 PP == domain 7 score: 26.8 bits; conditional E-value: 5.8e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHEKHLEI 265 899************************8 PP == domain 8 score: 27.2 bits; conditional E-value: 4.4e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIA 306 899************************96 PP == domain 9 score: 28.2 bits; conditional E-value: 2.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 317 NAYGSLGNAYRSLGDFRKAIEYHEKHLEIA 346 59**************************96 PP == domain 10 score: 27.9 bits; conditional E-value: 2.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ +Gnay++lg++ +A+ey ek Le+ FUN_002335-T1 357 NAYGSRGNAYQSLGDFRKAIEYHEKHLEIA 386 59**************************96 PP == domain 11 score: 28.2 bits; conditional E-value: 2.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 397 NAYGSLGNAYRSLGDFRKAIEYHEKHLEIA 426 59**************************96 PP == domain 12 score: 28.2 bits; conditional E-value: 2.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 437 NAYGSLGNAYRSLGDFRKAIEYHEKHLEIA 466 59**************************96 PP == domain 13 score: 27.2 bits; conditional E-value: 4.4e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHEKHLEIA 506 899************************96 PP == domain 14 score: 27.2 bits; conditional E-value: 4.4e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek Le+ FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEYHEKHLEIA 546 899************************96 PP == domain 15 score: 24.6 bits; conditional E-value: 2.9e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lGnay++lg++ +A+ey ek L++ FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIEYHEKYLKI 585 899*********************9998 PP == domain 16 score: 24.6 bits; conditional E-value: 2.8e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lG ay lg+ ++A+e yek Le+ FUN_002335-T1 597 NAYGSLGIAYSLLGDVQKAIELYEKHLEIA 626 59**************************96 PP == domain 17 score: 12.8 bits; conditional E-value: 0.00015 TPR_1 3 alynlGnayfklgkydeAle 22 a+ n+G yf+lg+++ Al+ FUN_002335-T1 638 AYHNMGGEYFSLGQFENALD 657 9*****************98 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.4 0.0 0.00099 0.74 4 32 .. 12 40 .. 11 43 .. 0.89 2 ! 13.9 0.0 7.7e-05 0.058 4 34 .. 52 82 .. 50 83 .. 0.90 3 ! 22.0 0.0 2.2e-07 0.00017 4 36 .. 92 124 .. 90 126 .. 0.95 4 ! 20.5 0.0 6.5e-07 0.00049 4 35 .. 132 163 .. 131 166 .. 0.95 5 ! 22.7 0.0 1.3e-07 0.0001 3 36 .. 171 204 .. 170 206 .. 0.95 6 ? 0.5 0.0 1.3 9.8e+02 10 28 .. 211 229 .. 210 232 .. 0.59 7 ! 15.2 0.0 3e-05 0.023 4 35 .. 238 269 .. 237 272 .. 0.92 8 ! 18.2 0.0 3.5e-06 0.0027 4 36 .. 278 310 .. 277 312 .. 0.94 9 ! 18.7 0.0 2.4e-06 0.0018 4 36 .. 318 350 .. 316 352 .. 0.94 10 ! 13.6 0.0 9.5e-05 0.072 4 36 .. 358 390 .. 356 392 .. 0.90 11 ! 18.7 0.0 2.4e-06 0.0018 4 36 .. 398 430 .. 396 432 .. 0.94 12 ! 17.7 0.0 5.1e-06 0.0038 4 35 .. 438 469 .. 436 472 .. 0.94 13 ! 18.2 0.0 3.5e-06 0.0027 4 36 .. 478 510 .. 477 512 .. 0.94 14 ! 17.1 0.0 7.5e-06 0.0057 4 35 .. 518 549 .. 517 552 .. 0.94 15 ! 14.3 0.0 5.9e-05 0.045 4 34 .. 558 588 .. 557 589 .. 0.90 16 ! 12.4 0.0 0.00023 0.18 4 35 .. 598 629 .. 596 629 .. 0.94 17 ? 3.5 0.0 0.15 1.1e+02 4 22 .. 638 656 .. 637 657 .. 0.93 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00099 TPR_10 4 slnnLanalraqgryeeAeelleealair 32 s+ nLa a +++g++ A +++e+ l+i+ FUN_002335-T1 12 SYQNLAYAFQSLGDFRKAIKYHEKHLKIA 40 899********************977776 PP == domain 2 score: 13.9 bits; conditional E-value: 7.7e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A +++e+ l+i+ + FUN_002335-T1 52 AYGSLGNAYQSLGDFRKAIDYCEKYLKIAIE 82 7999*******************99988766 PP == domain 3 score: 22.0 bits; conditional E-value: 2.2e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairervl 36 ++ nL+na++++g++ A e++e+ l+i+++v+ FUN_002335-T1 92 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVC 124 89*****************************97 PP == domain 4 score: 20.5 bits; conditional E-value: 6.5e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++g++ A e++e+ l+i+++v FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 163 799**************************998 PP == domain 5 score: 22.7 bits; conditional E-value: 1.3e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairervl 36 s++ nL+na++++g++ A e++e+ l+i+++v+ FUN_002335-T1 171 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVC 204 79******************************97 PP == domain 6 score: 0.5 bits; conditional E-value: 1.3 TPR_10 10 nalraqgryeeAeelleea 28 na+ ++g+ ++e+++e+ FUN_002335-T1 211 NAYGSLGNAYQSLEIAKEV 229 5666666666666666666 PP == domain 7 score: 15.2 bits; conditional E-value: 3e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+ +v FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHEKHLEIANEV 269 7899********************99998887 PP == domain 8 score: 18.2 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairervl 36 ++ L+na++++g++ A e++e+ l+i+++v+ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVC 310 7899***************************97 PP == domain 9 score: 18.7 bits; conditional E-value: 2.4e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairervl 36 ++ L+na+r++g++ A e++e+ l+i+++v+ FUN_002335-T1 318 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVC 350 7999***************************97 PP == domain 10 score: 13.6 bits; conditional E-value: 9.5e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairervl 36 ++ +na++++g++ A e++e+ l+i+++v+ FUN_002335-T1 358 AYGSRGNAYQSLGDFRKAIEYHEKHLEIAKEVC 390 677779************************997 PP == domain 11 score: 18.7 bits; conditional E-value: 2.4e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairervl 36 ++ L+na+r++g++ A e++e+ l+i+++v+ FUN_002335-T1 398 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVC 430 7999***************************97 PP == domain 12 score: 17.7 bits; conditional E-value: 5.1e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+r++g++ A e++e+ l+i+++v FUN_002335-T1 438 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV 469 7999*************************998 PP == domain 13 score: 18.2 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairervl 36 ++ L+na++++g++ A e++e+ l+i+++v+ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVC 510 7899***************************97 PP == domain 14 score: 17.1 bits; conditional E-value: 7.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+++v FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV 549 7899*************************998 PP == domain 15 score: 14.3 bits; conditional E-value: 5.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++e+ l+i+ + FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIEYHEKYLKIAIE 588 7899********************9988766 PP == domain 16 score: 12.4 bits; conditional E-value: 0.00023 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+ a++ +g+ + A el+e+ l+i+++v FUN_002335-T1 598 AYGSLGIAYSLLGDVQKAIELYEKHLEIAKEV 629 7999************************9987 PP == domain 17 score: 3.5 bits; conditional E-value: 0.15 TPR_10 4 slnnLanalraqgryeeAe 22 +++n++ ++++g++e A+ FUN_002335-T1 638 AYHNMGGEYFSLGQFENAL 656 79**************997 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.5 4.4e-05 0.033 2 30 .. 11 39 .. 10 40 .. 0.89 2 ! 21.7 0.5 2.7e-07 0.0002 3 31 .. 52 80 .. 50 80 .. 0.94 3 ! 20.8 0.2 5.4e-07 0.00041 3 32 .. 92 121 .. 90 122 .. 0.91 4 ! 20.6 0.2 6.4e-07 0.00048 3 32 .. 132 161 .. 130 162 .. 0.92 5 ! 21.0 0.2 4.7e-07 0.00035 2 32 .. 171 201 .. 170 202 .. 0.92 6 ? 0.6 0.0 1.6 1.2e+03 3 14 .. 212 223 .. 209 231 .. 0.65 7 ! 17.9 0.1 4.4e-06 0.0033 3 31 .. 238 266 .. 236 268 .. 0.91 8 ! 18.0 0.1 4.3e-06 0.0032 3 32 .. 278 307 .. 276 308 .. 0.91 9 ! 18.3 0.2 3.3e-06 0.0025 3 32 .. 318 347 .. 316 348 .. 0.91 10 ! 16.4 0.2 1.4e-05 0.011 3 32 .. 358 387 .. 356 388 .. 0.91 11 ! 18.3 0.2 3.3e-06 0.0025 3 32 .. 398 427 .. 396 428 .. 0.91 12 ! 18.3 0.2 3.3e-06 0.0025 3 32 .. 438 467 .. 436 468 .. 0.91 13 ! 18.0 0.1 4.3e-06 0.0032 3 32 .. 478 507 .. 476 508 .. 0.91 14 ! 18.0 0.1 4.3e-06 0.0032 3 32 .. 518 547 .. 516 548 .. 0.91 15 ! 19.1 0.4 1.8e-06 0.0014 3 30 .. 558 585 .. 556 586 .. 0.94 16 ! 15.7 0.3 2.4e-05 0.018 3 32 .. 598 627 .. 596 628 .. 0.93 17 ! 7.6 0.1 0.0093 7 3 20 .. 638 655 .. 637 657 .. 0.94 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 4.4e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 ++y+nl+++ ++lgd+ +A++y ek l++ FUN_002335-T1 11 KSYQNLAYAFQSLGDFRKAIKYHEKHLKI 39 69********************8886665 PP == domain 2 score: 21.7 bits; conditional E-value: 2.7e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay lG++y++lgd+ +A+ y+ek l+++ FUN_002335-T1 52 AYGSLGNAYQSLGDFRKAIDYCEKYLKIA 80 89************************985 PP == domain 3 score: 20.8 bits; conditional E-value: 5.4e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 92 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 121 9********************999998875 PP == domain 4 score: 20.6 bits; conditional E-value: 6.4e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 161 8********************999998875 PP == domain 5 score: 21.0 bits; conditional E-value: 4.7e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 171 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 201 59********************999998875 PP == domain 6 score: 0.6 bits; conditional E-value: 1.6 TPR_8 3 ayynlGliylkl 14 ay lG++y++l FUN_002335-T1 212 AYGSLGNAYQSL 223 566666666665 PP == domain 7 score: 17.9 bits; conditional E-value: 4.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay lG++y++lgd+ +A+ey ek le++ FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHEKHLEIA 266 899******************99988887 PP == domain 8 score: 18.0 bits; conditional E-value: 4.3e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAK 307 899******************999998875 PP == domain 9 score: 18.3 bits; conditional E-value: 3.3e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 318 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAK 347 89*******************999998875 PP == domain 10 score: 16.4 bits; conditional E-value: 1.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay +G++y++lgd+ +A+ey ek le+++ FUN_002335-T1 358 AYGSRGNAYQSLGDFRKAIEYHEKHLEIAK 387 8999*****************999998875 PP == domain 11 score: 18.3 bits; conditional E-value: 3.3e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 398 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAK 427 89*******************999998875 PP == domain 12 score: 18.3 bits; conditional E-value: 3.3e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 438 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAK 467 89*******************999998875 PP == domain 13 score: 18.0 bits; conditional E-value: 4.3e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAK 507 899******************999998875 PP == domain 14 score: 18.0 bits; conditional E-value: 4.3e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAK 547 899******************999998875 PP == domain 15 score: 19.1 bits; conditional E-value: 1.8e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek l++ FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIEYHEKYLKI 585 899*********************9998 PP == domain 16 score: 15.7 bits; conditional E-value: 2.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG +y+ lgd ++A+e yek le+++ FUN_002335-T1 598 AYGSLGIAYSLLGDVQKAIELYEKHLEIAK 627 899*********************999975 PP == domain 17 score: 7.6 bits; conditional E-value: 0.0093 TPR_8 3 ayynlGliylklgdyeeA 20 ay+n+G y +lg++e+A FUN_002335-T1 638 AYHNMGGEYFSLGQFENA 655 8****************9 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 166.2 0.0 2e-51 1.5e-48 8 291 .] 855 1117 .. 850 1117 .. 0.87 Alignments for each domain: == domain 1 score: 166.2 bits; conditional E-value: 2e-51 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ Lviv dgaL +P++a ++ i ++ps+++ +s++++ ++ a l+vgnp+ + k FUN_002335-T1 855 YDAVIGPIEDLL-GPEDDDLVIVSDGALCFIPWAAVIESI---------RIRIVPSLKSyqlISSVPKVYHKKTGA--LLVGNPCLEQ----LK 932 8999***99997.77777*****************88886.........466777765422144444444444444..******9774....35 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 + lp +++E++++a++l+ +l+g++at+ ++++ + ++++++H+a+Hg + ++L++ n + ed L++++++ FUN_002335-T1 933 NPLHALPCAQKEVEMIAAILKN---TPLVGKQATKAEVMKRM-SSVGLIHIAAHGNEV-----TGQIALSP-NPGwtqfpkeEDYILKMSDVQA 1016 55699***************77...8***************9.************988.....88899974.4445889998************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g+v +g+gv g+ara++ aGa+sv++ lw dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002335-T1 1017 ANLR-ARLVVLSCCHSGRGRVLKGEGVVGIARAFMAAGARSVLVALWALDDEATMEFMKRFYQHLKEGKTASAAVHQSMKSLRESEE----FSE 1105 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002335-T1 1106 MWYWAPFQLIGD 1117 ***********7 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.3 0.0046 3.5 3 23 .. 12 32 .. 10 40 .. 0.91 2 ! 19.5 0.3 1.4e-06 0.001 3 31 .. 52 80 .. 50 82 .. 0.92 3 ! 14.9 0.4 4e-05 0.03 3 23 .. 92 112 .. 90 122 .. 0.89 4 ! 14.5 0.3 5.4e-05 0.041 3 23 .. 132 152 .. 130 162 .. 0.89 5 ! 14.8 0.3 4.4e-05 0.033 3 23 .. 172 192 .. 170 202 .. 0.89 6 ! 11.6 0.2 0.00047 0.35 3 23 .. 238 258 .. 237 267 .. 0.89 7 ! 11.7 0.3 0.00043 0.32 3 23 .. 278 298 .. 277 308 .. 0.87 8 ! 12.9 0.2 0.00018 0.14 3 23 .. 318 338 .. 316 348 .. 0.87 9 ! 11.8 0.2 0.00041 0.31 3 23 .. 358 378 .. 356 388 .. 0.87 10 ! 12.9 0.2 0.00018 0.14 3 23 .. 398 418 .. 396 428 .. 0.87 11 ! 12.9 0.2 0.00018 0.14 3 23 .. 438 458 .. 436 468 .. 0.87 12 ! 11.7 0.3 0.00043 0.32 3 23 .. 478 498 .. 477 508 .. 0.87 13 ! 11.7 0.3 0.00043 0.32 3 23 .. 518 538 .. 517 548 .. 0.87 14 ! 13.4 0.4 0.00012 0.092 3 30 .. 558 585 .. 557 588 .. 0.88 15 ! 15.3 0.2 3e-05 0.022 3 31 .. 598 626 .. 596 628 .. 0.88 16 ! 11.1 0.1 0.0007 0.52 3 29 .. 638 664 .. 636 668 .. 0.91 17 ? -0.2 0.0 2.8 2.1e+03 10 25 .. 697 712 .. 696 717 .. 0.84 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0046 TPR_2 3 alynlGlayyklgdyeeAlea 23 + nl++a lgd+ +A+++ FUN_002335-T1 12 SYQNLAYAFQSLGDFRKAIKY 32 689****************98 PP == domain 2 score: 19.5 bits; conditional E-value: 1.4e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ lG+ay lgd+ +A++++ek l+++ FUN_002335-T1 52 AYGSLGNAYQSLGDFRKAIDYCEKYLKIA 80 7888**********************985 PP == domain 3 score: 14.9 bits; conditional E-value: 4e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002335-T1 92 AYGNLGNAYQSLGDFRKAIEY 112 899*****************9 PP == domain 4 score: 14.5 bits; conditional E-value: 5.4e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEY 152 799*****************9 PP == domain 5 score: 14.8 bits; conditional E-value: 4.4e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002335-T1 172 AYGNLGNAYQSLGDFRKAIEY 192 899*****************9 PP == domain 6 score: 11.6 bits; conditional E-value: 0.00047 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEY 258 57789**************98 PP == domain 7 score: 11.7 bits; conditional E-value: 0.00043 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEY 298 57789***************9 PP == domain 8 score: 12.9 bits; conditional E-value: 0.00018 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002335-T1 318 AYGSLGNAYRSLGDFRKAIEY 338 7888****************8 PP == domain 9 score: 11.8 bits; conditional E-value: 0.00041 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ +G+ay lgd+ +A+e+ FUN_002335-T1 358 AYGSRGNAYQSLGDFRKAIEY 378 78889***************8 PP == domain 10 score: 12.9 bits; conditional E-value: 0.00018 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002335-T1 398 AYGSLGNAYRSLGDFRKAIEY 418 7888****************8 PP == domain 11 score: 12.9 bits; conditional E-value: 0.00018 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002335-T1 438 AYGSLGNAYRSLGDFRKAIEY 458 7888****************8 PP == domain 12 score: 11.7 bits; conditional E-value: 0.00043 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEY 498 57789***************9 PP == domain 13 score: 11.7 bits; conditional E-value: 0.00043 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEY 538 57789***************9 PP == domain 14 score: 13.4 bits; conditional E-value: 0.00012 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a+ lG+ay lgd+ +A+e+ ek l++ FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIEYHEKYLKI 585 5778*****************8888877 PP == domain 15 score: 15.3 bits; conditional E-value: 3e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ lG ay lgd ++A+e+yek le++ FUN_002335-T1 598 AYGSLGIAYSLLGDVQKAIELYEKHLEIA 626 7888*******************977765 PP == domain 16 score: 11.1 bits; conditional E-value: 0.0007 TPR_2 3 alynlGlayyklgdyeeAleayekAle 29 a++n+G y+ lg++e Al+ + A+e FUN_002335-T1 638 AYHNMGGEYFSLGQFENALDKFVYAVE 664 89********************99887 PP == domain 17 score: -0.2 bits; conditional E-value: 2.8 TPR_2 10 ayyklgdyeeAleaye 25 ++++ g++ eAl a e FUN_002335-T1 697 SLLRIGKFREALFAAE 712 67899*******9877 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.044 33 4 29 .. 13 38 .. 10 42 .. 0.89 2 ! 8.6 0.0 0.0066 5 5 29 .. 54 78 .. 51 80 .. 0.89 3 ? 6.5 0.0 0.032 24 6 30 .. 95 119 .. 91 123 .. 0.86 4 ? 6.5 0.0 0.033 25 6 31 .. 135 160 .. 131 165 .. 0.86 5 ? 6.3 0.0 0.038 28 6 30 .. 175 199 .. 171 203 .. 0.87 6 ? 6.7 0.0 0.027 21 6 30 .. 241 265 .. 237 271 .. 0.86 7 ? 6.6 0.0 0.031 23 6 30 .. 281 305 .. 277 309 .. 0.87 8 ! 8.5 0.0 0.0071 5.3 5 30 .. 320 345 .. 317 349 .. 0.86 9 ? 5.9 0.0 0.05 38 6 30 .. 361 385 .. 357 389 .. 0.85 10 ! 8.5 0.0 0.0071 5.3 5 30 .. 400 425 .. 397 429 .. 0.86 11 ! 8.7 0.0 0.0061 4.6 5 31 .. 440 466 .. 437 471 .. 0.86 12 ? 6.6 0.0 0.031 23 6 30 .. 481 505 .. 477 509 .. 0.87 13 ? 6.8 0.0 0.027 20 6 31 .. 521 546 .. 517 551 .. 0.86 14 ? 7.8 0.0 0.012 9 6 29 .. 561 584 .. 557 587 .. 0.90 15 ? 7.2 0.0 0.019 15 6 31 .. 601 626 .. 597 631 .. 0.85 16 ? -0.8 0.1 7.4 5.6e+03 10 31 .. 697 718 .. 696 730 .. 0.73 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.044 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ la+a+ lGd+ +A+++ e+ l+ FUN_002335-T1 13 YQNLAYAFQSLGDFRKAIKYHEKHLK 38 6789****************999887 PP == domain 2 score: 8.6 bits; conditional E-value: 0.0066 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+++ e++l+ FUN_002335-T1 54 GSLGNAYQSLGDFRKAIDYCEKYLK 78 5799******************998 PP == domain 3 score: 6.5 bits; conditional E-value: 0.032 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 95 NLGNAYQSLGDFRKAIEYHEKHLEI 119 689***************9998876 PP == domain 4 score: 6.5 bits; conditional E-value: 0.033 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 135 NLGNAYQSLGDFRKAIEYHEKHLEIA 160 589***************99998865 PP == domain 5 score: 6.3 bits; conditional E-value: 0.038 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 175 NLGNAYQSLGDFRKAIEYHEKHLEI 199 5899**************9998876 PP == domain 6 score: 6.7 bits; conditional E-value: 0.027 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 241 SLGNAYQSLGDFRKAIEYHEKHLEI 265 699***************9999886 PP == domain 7 score: 6.6 bits; conditional E-value: 0.031 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 281 SLGNAYQSLGDFRKAIEYHEKHLEI 305 699***************9998876 PP == domain 8 score: 8.5 bits; conditional E-value: 0.0071 TPR_14 5 lalarallalGdpdeAlelleralal 30 l++a++ lGd+ +A+e+ e+ l+ FUN_002335-T1 320 GSLGNAYRSLGDFRKAIEYHEKHLEI 345 5799***************9998876 PP == domain 9 score: 5.9 bits; conditional E-value: 0.05 TPR_14 6 alarallalGdpdeAlelleralal 30 +++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 361 SRGNAYQSLGDFRKAIEYHEKHLEI 385 6899**************9998876 PP == domain 10 score: 8.5 bits; conditional E-value: 0.0071 TPR_14 5 lalarallalGdpdeAlelleralal 30 l++a++ lGd+ +A+e+ e+ l+ FUN_002335-T1 400 GSLGNAYRSLGDFRKAIEYHEKHLEI 425 5799***************9998876 PP == domain 11 score: 8.7 bits; conditional E-value: 0.0061 TPR_14 5 lalarallalGdpdeAlelleralald 31 l++a++ lGd+ +A+e+ e+ l+ FUN_002335-T1 440 GSLGNAYRSLGDFRKAIEYHEKHLEIA 466 5799***************99998865 PP == domain 12 score: 6.6 bits; conditional E-value: 0.031 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 481 SLGNAYQSLGDFRKAIEYHEKHLEI 505 699***************9998876 PP == domain 13 score: 6.8 bits; conditional E-value: 0.027 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002335-T1 521 SLGNAYQSLGDFRKAIEYHEKHLEIA 546 699***************99998865 PP == domain 14 score: 7.8 bits; conditional E-value: 0.012 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e++l+ FUN_002335-T1 561 SLGNAYQSLGDFRKAIEYHEKYLK 584 699******************998 PP == domain 15 score: 7.2 bits; conditional E-value: 0.019 TPR_14 6 alarallalGdpdeAlelleralald 31 l+ a+ lGd ++A+el+e+ l+ FUN_002335-T1 601 SLGIAYSLLGDVQKAIELYEKHLEIA 626 688999***************99865 PP == domain 16 score: -0.8 bits; conditional E-value: 7.4 TPR_14 10 allalGdpdeAlelleralald 31 ll+ G++ eAl ++e + a+ FUN_002335-T1 697 SLLRIGKFREALFAAETGRAQA 718 68999*******9999887764 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.39 3e+02 49 75 .. 16 42 .. 4 47 .. 0.82 2 ? 5.7 0.1 0.03 22 41 76 .. 48 83 .. 27 86 .. 0.78 3 ! 8.4 0.0 0.0043 3.2 46 76 .. 93 123 .. 84 127 .. 0.89 4 ! 11.8 0.0 0.00036 0.27 34 78 .. 121 165 .. 120 167 .. 0.91 5 ! 10.0 0.0 0.0014 1 36 76 .. 163 203 .. 161 206 .. 0.88 6 ! 12.8 0.0 0.00018 0.14 32 78 .. 225 271 .. 218 273 .. 0.91 7 ! 8.7 0.0 0.0033 2.5 45 76 .. 278 309 .. 269 312 .. 0.86 8 ! 11.6 0.0 0.00042 0.31 34 76 .. 307 349 .. 307 353 .. 0.93 9 ! 8.5 0.0 0.004 3 34 76 .. 347 389 .. 346 392 .. 0.90 10 ! 12.2 0.0 0.00026 0.2 34 76 .. 387 429 .. 385 432 .. 0.93 11 ! 13.6 0.0 9.7e-05 0.073 34 78 .. 427 471 .. 424 473 .. 0.93 12 ! 8.8 0.0 0.0031 2.4 45 76 .. 478 509 .. 469 513 .. 0.86 13 ! 11.7 0.0 0.00038 0.28 35 78 .. 508 551 .. 507 553 .. 0.91 14 ? 6.0 0.0 0.024 18 46 78 .. 559 591 .. 550 593 .. 0.86 15 ? 0.9 0.0 0.89 6.7e+02 45 78 .. 598 631 .. 588 633 .. 0.85 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.39 Rapsyn_N 49 litahsemGkykealefslaqlniaee 75 l a +G ++ a+++ + l ia e FUN_002335-T1 16 LAYAFQSLGDFRKAIKYHEKHLKIAIE 42 56688899************9999977 PP == domain 2 score: 5.7 bits; conditional E-value: 0.03 Rapsyn_N 41 dkfrllGylitahsemGkykealefslaqlniaeel 76 + + G l +a+ +G ++ a+++ + l ia e+ FUN_002335-T1 48 GEGNAYGSLGNAYQSLGDFRKAIDYCEKYLKIAIEV 83 4456789999*********************99886 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0043 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 93 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 123 688999***********************97 PP == domain 4 score: 11.8 bits; conditional E-value: 0.00036 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 k+ +dr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002335-T1 121 KEVCDRVGEGGAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSD 165 5678898888999*****************************976 PP == domain 5 score: 10.0 bits; conditional E-value: 0.0014 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeel 76 sdr + G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 163 VSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 203 6777778888999**************************97 PP == domain 6 score: 12.8 bits; conditional E-value: 0.00018 Rapsyn_N 32 vlkktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 + k+ +dr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002335-T1 225 IAKEVCDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIANEVSD 271 66889999999999******************************976 PP == domain 7 score: 8.7 bits; conditional E-value: 0.0033 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV 309 5688999***********************97 PP == domain 8 score: 11.6 bits; conditional E-value: 0.00042 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 k+ +dr + + G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 307 KEVCDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV 349 567999999999*****************************97 PP == domain 9 score: 8.5 bits; conditional E-value: 0.004 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 k+ +dr + + G +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 347 KEVCDRVGEGNAYGSRGNAYQSLGDFRKAIEYHEKHLEIAKEV 389 567888888899999999***********************97 PP == domain 10 score: 12.2 bits; conditional E-value: 0.00026 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 k+ +dr + + G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 387 KEVCDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV 429 7889999999*******************************97 PP == domain 11 score: 13.6 bits; conditional E-value: 9.7e-05 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 k+ +dr + + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002335-T1 427 KEVCDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVSD 471 7899**************************************976 PP == domain 12 score: 8.8 bits; conditional E-value: 0.0031 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV 509 5688999***********************97 PP == domain 13 score: 11.7 bits; conditional E-value: 0.00038 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 + +dr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002335-T1 508 EVCDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSD 551 6788888888999****************************976 PP == domain 14 score: 6.0 bits; conditional E-value: 0.024 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l ia e+ d FUN_002335-T1 559 YGSLGNAYQSLGDFRKAIEYHEKYLKIAIEVGD 591 6889999********************999865 PP == domain 15 score: 0.9 bits; conditional E-value: 0.89 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeeled 78 G l a+s +G + a+e+ + l+ia+e+ d FUN_002335-T1 598 AYGSLGIAYSLLGDVQKAIELYEKHLEIAKEVGD 631 56888899999********************876 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.0 1.3e-07 9.8e-05 13 192 .. 22 201 .. 15 204 .. 0.84 2 ! 10.6 0.0 0.00047 0.35 14 115 .. 103 205 .. 100 232 .. 0.85 3 ! 16.8 0.0 6e-06 0.0045 42 187 .. 238 382 .. 219 388 .. 0.73 4 ! 15.3 0.0 1.7e-05 0.013 43 191 .. 359 506 .. 351 509 .. 0.65 5 ! 10.6 0.0 0.00045 0.34 12 112 .. 487 588 .. 482 593 .. 0.81 6 ? 5.9 0.0 0.012 9.2 14 103 .. 569 659 .. 564 668 .. 0.71 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 1.3e-07 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+++ ++ L++ e + + + a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ ++ G++++A+e ++ l FUN_002335-T1 22 SLGDFRKAIKYHEKHLKIAIEAGHRVGeGNAYGSLGNAYQSLGDFRKAIDYCEKYLKIAIEVGHRVGEGNAYGNLGNAYQSLGDFRKAIEYHEKHL 117 568888888888888888888888887789999999999999999999999999999999999998899999999999999999999999999999 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerlar 192 + a+e + + g+++ l++ + +d+ +A ++ ++ +++++++ ++ ay l + ++ G+ + A ++ ++ ++a+ FUN_002335-T1 118 EIAKEVCDRV--GEGGAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVsDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 201 9999999995..88899999999999999999999999999999999966688888888888888888888888888877766665 PP == domain 2 score: 10.6 bits; conditional E-value: 0.00047 TPR_MalT 14 qgeaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 g++ +a+e+ ++ L++ +e d++ + +++ +lG a++ +gd+ +A + ++ ++a++ + a+ +++ ++ G++++A+e ++ l FUN_002335-T1 103 LGDFRKAIEYHEKHLEIAKEvcDRVGEGGAY-GNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHL 197 5788888888888888888755666665555.9*************999999999999988888888999999*********************** PP TPR_MalT 108 qlaqeskl 115 + a+e + FUN_002335-T1 198 EIAKEVCD 205 99998765 PP == domain 3 score: 16.8 bits; conditional E-value: 6e-06 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 a+ +lG a++ +gd+ +A + ++ ++a + + a+ ++++ ++ G++++A+e ++ l+ a+e + + g ++ +l++ ++ +d FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHEKHLEIANEVSDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVCDRV--GEGNAYGSLGNAYRSLGD 331 5577888888888888777777777777766666666788888888888888888888888888888888888885..777888888888888888 PP TPR_MalT 138 LeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqra 187 + +A ++ ++ +++++++ ++ +ay + ++ G+ + A ++ ++ FUN_002335-T1 332 FRKAIEYHEKHLEIAKEVcDRVGEGNAYGSRGNAYQSLGDFRKAIEYHEKH 382 888888888888888887666666666666666666666666666655555 PP == domain 4 score: 15.3 bits; conditional E-value: 1.7e-05 TPR_MalT 43 tlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwndL 138 + + G a++ +gd+ +A + ++ ++a++ + a+ ++++ +r G++++A+e ++ l+ a+e + + g ++ +l++ ++ +d+ FUN_002335-T1 359 YGSRGNAYQSLGDFRKAIEYHEKHLEIAKEVCDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVCDRV--GEGNAYGSLGNAYRSLGDF 452 556677777777777666666666666655555555666777777777777777777777777777777777774..6667777777777777777 PP TPR_MalT 139 eeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerla 191 +A ++ ++ +++++++ ++ ay l + ++ G+ + A ++ ++ ++a FUN_002335-T1 453 RKAIEYHEKHLEIAKEVsDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIA 506 777777777777777774456666666666666666666666666666555544 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00045 TPR_MalT 12 vsqgeaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 s g++ +a+e+ ++ L++ +e d++ + +++ +lG a++ +gd+ +A + ++ ++a++ + a+ ++++ ++ G++++A+e ++ FUN_002335-T1 487 QSLGDFRKAIEYHEKHLEIAKEvcDRVGEGGAY-GSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEK 581 566888888888888888888755666655555.99999999999999999988888888888888888899999999999999999999999999 PP TPR_MalT 106 alqlaqe 112 l+ a e FUN_002335-T1 582 YLKIAIE 588 9988876 PP == domain 6 score: 5.9 bits; conditional E-value: 0.012 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaety 103 g++ +a+e+ ++ L++ e d + a+ +lG a+ l+gd+++A + +++ ++a++ ++ + +a+ + ++ Gq+ +A++ + FUN_002335-T1 569 LGDFRKAIEYHEKYLKIAIEvGDRVGEGNAYGSLGIAYSLLGDVQKAIELYEKHLEIAKEVGDRKGEGIAYHNMGGEYFSLGQFENALDKF 659 5677777777777777643323334457778999999999999999999999999988888887777777777777777777777776655 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.1 0.041 31 14 33 .. 11 30 .. 10 31 .. 0.92 2 ? 5.0 0.0 0.065 49 14 33 .. 51 70 .. 49 71 .. 0.92 3 ! 8.5 0.1 0.005 3.8 14 34 .] 91 111 .. 89 111 .. 0.93 4 ? 7.5 0.1 0.011 8.2 15 34 .] 132 151 .. 130 151 .. 0.93 5 ! 7.9 0.1 0.0077 5.8 14 34 .] 171 191 .. 169 191 .. 0.92 6 ? 4.6 0.0 0.091 68 15 34 .] 238 257 .. 236 257 .. 0.92 7 ? 4.6 0.0 0.091 68 15 34 .] 278 297 .. 276 297 .. 0.92 8 ? 5.6 0.0 0.042 32 14 34 .] 317 337 .. 315 337 .. 0.92 9 ? 3.8 0.0 0.16 1.2e+02 14 34 .] 357 377 .. 355 377 .. 0.92 10 ? 5.6 0.0 0.042 32 14 34 .] 397 417 .. 395 417 .. 0.92 11 ? 5.6 0.0 0.042 32 14 34 .] 437 457 .. 435 457 .. 0.92 12 ? 4.6 0.0 0.091 68 15 34 .] 478 497 .. 476 497 .. 0.92 13 ? 4.6 0.0 0.091 68 15 34 .] 518 537 .. 516 537 .. 0.92 14 ? 4.6 0.0 0.091 68 15 34 .] 558 577 .. 556 577 .. 0.92 15 ? 6.8 0.0 0.018 14 14 34 .] 597 617 .. 595 617 .. 0.93 16 ? -1.2 0.0 6.5 4.9e+03 15 33 .. 638 656 .. 636 657 .. 0.85 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.041 TPR_17 14 dayynLArlllnnGqleeAl 33 ++y+nLA++ + +G++ +A+ FUN_002335-T1 11 KSYQNLAYAFQSLGDFRKAI 30 58***************998 PP == domain 2 score: 5.0 bits; conditional E-value: 0.065 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay L+++++ +G++ +A+ FUN_002335-T1 51 NAYGSLGNAYQSLGDFRKAI 70 79**************9997 PP == domain 3 score: 8.5 bits; conditional E-value: 0.005 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002335-T1 91 NAYGNLGNAYQSLGDFRKAIE 111 79****************985 PP == domain 4 score: 7.5 bits; conditional E-value: 0.011 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIE 151 89***************985 PP == domain 5 score: 7.9 bits; conditional E-value: 0.0077 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002335-T1 171 SAYGNLGNAYQSLGDFRKAIE 191 59****************985 PP == domain 6 score: 4.6 bits; conditional E-value: 0.091 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIE 257 8999*************985 PP == domain 7 score: 4.6 bits; conditional E-value: 0.091 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIE 297 8999*************985 PP == domain 8 score: 5.6 bits; conditional E-value: 0.042 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002335-T1 317 NAYGSLGNAYRSLGDFRKAIE 337 79****************985 PP == domain 9 score: 3.8 bits; conditional E-value: 0.16 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay ++++++ +G++ +A++ FUN_002335-T1 357 NAYGSRGNAYQSLGDFRKAIE 377 7999**************985 PP == domain 10 score: 5.6 bits; conditional E-value: 0.042 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002335-T1 397 NAYGSLGNAYRSLGDFRKAIE 417 79****************985 PP == domain 11 score: 5.6 bits; conditional E-value: 0.042 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002335-T1 437 NAYGSLGNAYRSLGDFRKAIE 457 79****************985 PP == domain 12 score: 4.6 bits; conditional E-value: 0.091 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIE 497 8999*************985 PP == domain 13 score: 4.6 bits; conditional E-value: 0.091 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIE 537 8999*************985 PP == domain 14 score: 4.6 bits; conditional E-value: 0.091 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIE 577 8999*************985 PP == domain 15 score: 6.8 bits; conditional E-value: 0.018 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G+ ++A++ FUN_002335-T1 597 NAYGSLGIAYSLLGDVQKAIE 617 79*****************85 PP == domain 16 score: -1.2 bits; conditional E-value: 6.5 TPR_17 15 ayynLArlllnnGqleeAl 33 ay+n++ + +Gq+e Al FUN_002335-T1 638 AYHNMGGEYFSLGQFENAL 656 8999999999999999886 PP >> BAG6 BCL2-associated athanogene 6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 1.9 1.4e+03 53 69 .. 51 67 .. 44 74 .. 0.82 2 ? 0.3 0.0 1.1 8.3e+02 53 72 .. 91 110 .. 82 116 .. 0.80 3 ? 5.7 0.0 0.023 18 37 71 .. 113 149 .. 98 154 .. 0.83 4 ? 5.2 0.0 0.034 26 37 73 .. 153 191 .. 148 201 .. 0.83 5 ? 4.8 0.0 0.046 34 38 72 .. 220 256 .. 212 263 .. 0.84 6 ? 5.0 0.0 0.039 29 37 72 .. 259 296 .. 254 302 .. 0.84 7 ? 5.6 0.0 0.025 19 37 73 .. 299 337 .. 295 347 .. 0.83 8 ? 0.9 0.0 0.76 5.7e+02 37 72 .. 339 376 .. 334 383 .. 0.81 9 ? 5.8 0.0 0.022 16 37 72 .. 379 416 .. 366 423 .. 0.83 10 ? 5.5 0.0 0.028 21 37 72 .. 419 456 .. 413 461 .. 0.83 11 ? 4.7 0.0 0.05 38 37 72 .. 459 496 .. 454 501 .. 0.83 12 ? 5.4 0.0 0.03 23 37 72 .. 499 536 .. 494 541 .. 0.84 13 ? 4.7 0.0 0.05 38 37 72 .. 539 576 .. 534 581 .. 0.83 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 1.9 BAG6 53 EalhllshalhalSDlr 69 +a+ +l++a+ +l+D r FUN_002335-T1 51 NAYGSLGNAYQSLGDFR 67 57889**********98 PP == domain 2 score: 0.3 bits; conditional E-value: 1.1 BAG6 53 EalhllshalhalSDlrlnl 72 +a+ +l++a+ +l+D r ++ FUN_002335-T1 91 NAYGNLGNAYQSLGDFRKAI 110 57889**********98665 PP == domain 3 score: 5.7 bits; conditional E-value: 0.023 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrln 71 +++++e + +++drv+E a+ +l++a+ +l+D r + FUN_002335-T1 113 HEKHLEIAKEVCDRVGEggAYGNLGNAYQSLGDFRKA 149 457799999******997789************9865 PP == domain 4 score: 5.2 bits; conditional E-value: 0.034 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnls 73 +++++e + ++ drv+E a+ +l++a+ +l+D r +++ FUN_002335-T1 153 HEKHLEIAKEVSDRVGEgsAYGNLGNAYQSLGDFRKAIE 191 4577899999*****99778999**********987665 PP == domain 5 score: 4.8 bits; conditional E-value: 0.046 BAG6 38 teereedqrildrvsE..alhllshalhalSDlrlnl 72 + +e + +++drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 220 YQSLEIAKEVCDRVGEggAYGSLGNAYQSLGDFRKAI 256 567888999*****9977899***********98666 PP == domain 6 score: 5.0 bits; conditional E-value: 0.039 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e ++++ drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 259 HEKHLEIANEVSDRVGEggAYGSLGNAYQSLGDFRKAI 296 4677899999*****9977899***********98665 PP == domain 7 score: 5.6 bits; conditional E-value: 0.025 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnls 73 +++++e + +++drv+E a+ +l++a+ +l+D r +++ FUN_002335-T1 299 HEKHLEIAKEVCDRVGEgnAYGSLGNAYRSLGDFRKAIE 337 4677899999*****9866899***********987665 PP == domain 8 score: 0.9 bits; conditional E-value: 0.76 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e + +++drv+E a+ + ++a+ +l+D r ++ FUN_002335-T1 339 HEKHLEIAKEVCDRVGEgnAYGSRGNAYQSLGDFRKAI 376 4577899999*****9866789999********98666 PP == domain 9 score: 5.8 bits; conditional E-value: 0.022 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e + +++drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 379 HEKHLEIAKEVCDRVGEgnAYGSLGNAYRSLGDFRKAI 416 467799999******9866899***********98666 PP == domain 10 score: 5.5 bits; conditional E-value: 0.028 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e + +++drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 419 HEKHLEIAKEVCDRVGEgnAYGSLGNAYRSLGDFRKAI 456 4577899999*****9866899***********98665 PP == domain 11 score: 4.7 bits; conditional E-value: 0.05 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e + ++ drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 459 HEKHLEIAKEVSDRVGEggAYGSLGNAYQSLGDFRKAI 496 4577899999*****9977899***********98665 PP == domain 12 score: 5.4 bits; conditional E-value: 0.03 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e + +++drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 499 HEKHLEIAKEVCDRVGEggAYGSLGNAYQSLGDFRKAI 536 467789999******9977899***********98665 PP == domain 13 score: 4.7 bits; conditional E-value: 0.05 BAG6 37 nteereedqrildrvsE..alhllshalhalSDlrlnl 72 +++++e + ++ drv+E a+ +l++a+ +l+D r ++ FUN_002335-T1 539 HEKHLEIAKEVSDRVGEggAYGSLGNAYQSLGDFRKAI 576 4577899999*****9977899***********98665 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.1 0.18 1.4e+02 5 22 .. 15 32 .. 11 34 .. 0.90 2 ! 8.3 0.1 0.0079 5.9 6 28 .. 56 78 .. 55 79 .. 0.94 3 ? 3.8 0.0 0.21 1.6e+02 5 22 .. 95 112 .. 92 114 .. 0.92 4 ? 3.7 0.0 0.23 1.7e+02 6 22 .. 136 152 .. 135 154 .. 0.92 5 ? 3.8 0.0 0.21 1.6e+02 5 22 .. 175 192 .. 172 194 .. 0.92 6 ? 2.9 0.0 0.41 3e+02 6 22 .. 242 258 .. 241 260 .. 0.93 7 ? 2.9 0.0 0.41 3e+02 6 22 .. 282 298 .. 281 300 .. 0.93 8 ? 3.3 0.0 0.3 2.3e+02 6 22 .. 322 338 .. 321 340 .. 0.93 9 ? 1.6 0.0 1 7.8e+02 7 22 .. 363 378 .. 362 380 .. 0.91 10 ? 3.3 0.0 0.3 2.3e+02 6 22 .. 402 418 .. 401 420 .. 0.93 11 ? 3.3 0.0 0.3 2.3e+02 6 22 .. 442 458 .. 441 460 .. 0.93 12 ? 2.9 0.0 0.41 3e+02 6 22 .. 482 498 .. 481 500 .. 0.93 13 ? 2.9 0.0 0.41 3e+02 6 22 .. 522 538 .. 521 540 .. 0.93 14 ? 4.2 0.0 0.16 1.2e+02 6 27 .. 562 583 .. 561 585 .. 0.85 15 ? 7.3 0.0 0.016 12 6 25 .. 602 621 .. 601 623 .. 0.94 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.18 TPR_6 5 klalsylelgdkdeAkaa 22 +la++++ lgd+ +A+++ FUN_002335-T1 15 NLAYAFQSLGDFRKAIKY 32 79*************986 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0079 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 l+ +y+ lgd+ +A+++ ++++k FUN_002335-T1 56 LGNAYQSLGDFRKAIDYCEKYLK 78 799*****************987 PP == domain 3 score: 3.8 bits; conditional E-value: 0.21 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002335-T1 95 NLGNAYQSLGDFRKAIEY 112 599************986 PP == domain 4 score: 3.7 bits; conditional E-value: 0.23 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 136 LGNAYQSLGDFRKAIEY 152 89************986 PP == domain 5 score: 3.8 bits; conditional E-value: 0.21 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002335-T1 175 NLGNAYQSLGDFRKAIEY 192 599************986 PP == domain 6 score: 2.9 bits; conditional E-value: 0.41 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 242 LGNAYQSLGDFRKAIEY 258 799***********986 PP == domain 7 score: 2.9 bits; conditional E-value: 0.41 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 282 LGNAYQSLGDFRKAIEY 298 799***********986 PP == domain 8 score: 3.3 bits; conditional E-value: 0.3 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 322 LGNAYRSLGDFRKAIEY 338 799***********986 PP == domain 9 score: 1.6 bits; conditional E-value: 1 TPR_6 7 alsylelgdkdeAkaa 22 + +y+ lgd+ +A+++ FUN_002335-T1 363 GNAYQSLGDFRKAIEY 378 889**********986 PP == domain 10 score: 3.3 bits; conditional E-value: 0.3 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 402 LGNAYRSLGDFRKAIEY 418 799***********986 PP == domain 11 score: 3.3 bits; conditional E-value: 0.3 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 442 LGNAYRSLGDFRKAIEY 458 799***********986 PP == domain 12 score: 2.9 bits; conditional E-value: 0.41 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 482 LGNAYQSLGDFRKAIEY 498 799***********986 PP == domain 13 score: 2.9 bits; conditional E-value: 0.41 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002335-T1 522 LGNAYQSLGDFRKAIEY 538 799***********986 PP == domain 14 score: 4.2 bits; conditional E-value: 0.16 TPR_6 6 lalsylelgdkdeAkaalqrli 27 l+ +y+ lgd+ +A+++ ++++ FUN_002335-T1 562 LGNAYQSLGDFRKAIEYHEKYL 583 799************9866655 PP == domain 15 score: 7.3 bits; conditional E-value: 0.016 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y lgd ++A++++++ FUN_002335-T1 602 LGIAYSLLGDVQKAIELYEK 621 799***************97 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 9.3 7e+03 25 67 .. 20 65 .. 16 71 .. 0.63 2 ! 7.4 0.0 0.0087 6.5 23 70 .. 98 148 .. 74 156 .. 0.82 3 ? 4.8 0.0 0.059 45 24 67 .. 139 185 .. 135 188 .. 0.79 4 ? 7.0 0.0 0.012 9.2 24 65 .. 179 223 .. 173 235 .. 0.83 5 ? 2.5 0.0 0.31 2.3e+02 24 64 .. 245 288 .. 240 291 .. 0.81 6 ! 8.7 0.0 0.0036 2.7 24 70 .. 285 334 .. 278 346 .. 0.81 7 ? 1.9 0.0 0.46 3.5e+02 26 54 .. 327 355 .. 323 365 .. 0.85 8 ! 7.5 0.0 0.0087 6.5 24 67 .. 365 411 .. 360 414 .. 0.82 9 ! 7.4 0.0 0.0093 7 26 70 .. 407 454 .. 402 463 .. 0.80 10 ? 3.5 0.0 0.15 1.1e+02 26 69 .. 447 493 .. 442 497 .. 0.82 11 ? 7.1 0.0 0.011 8.2 24 67 .. 485 531 .. 480 534 .. 0.83 12 ? 5.2 0.0 0.045 34 24 70 .. 525 574 .. 521 584 .. 0.83 13 ? -1.6 0.0 5.9 4.4e+03 22 45 .. 656 680 .. 652 685 .. 0.76 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 9.3 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkard 67 f+s + ++A+ +e+ + ++ ++ sLgn +++ d FUN_002335-T1 20 FQSLGDFRKAIKYHEKHLKIAIEAGHRVgegNAYGSLGNAYQSLGD 65 6777788888888887766666666666332234566666666555 PP == domain 2 score: 7.4 bits; conditional E-value: 0.0087 WH_Halo_primase 23 gefhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 ++ +s + ++A+e +e+ e ++v++++ + +Lgn +++ d r+ FUN_002335-T1 98 NAYQSLGDFRKAIEYHEKHLEIAKEVCDRVGEggaYGNLGNAYQSLGDFRK 148 4678999***********************653336788888888777665 PP == domain 3 score: 4.8 bits; conditional E-value: 0.059 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkard 67 + +s + ++A+e +e+ e ++v +++ s +Lgn +++ d FUN_002335-T1 139 AYQSLGDFRKAIEYHEKHLEIAKEVSDRVgegSAYGNLGNAYQSLGD 185 678899***********************554445677777776555 PP == domain 4 score: 7.0 bits; conditional E-value: 0.012 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkka 65 + +s + ++A+e +e+ e ++v++++ sLgn +++ FUN_002335-T1 179 AYQSLGDFRKAIEYHEKHLEIAKEVCDRVgegNAYGSLGNAYQSL 223 678899***********************4443467999998875 PP == domain 5 score: 2.5 bits; conditional E-value: 0.31 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkk 64 + +s + ++A+e +e+ e ++v +++ + sLgn +++ FUN_002335-T1 245 AYQSLGDFRKAIEYHEKHLEIANEVSDRVGEggaYGSLGNAYQS 288 6788999*************999999999553337788888876 PP == domain 6 score: 8.7 bits; conditional E-value: 0.0036 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 + +s + ++A+e +e+ e ++v++++ + sLgn +++ d r+ FUN_002335-T1 285 AYQSLGDFRKAIEYHEKHLEIAKEVCDRVGEgnaYGSLGNAYRSLGDFRK 334 678899***********************553446789999888877766 PP == domain 7 score: 1.9 bits; conditional E-value: 0.46 WH_Halo_primase 26 hsarelydAleaYepereweqkvkneiss 54 s + ++A+e +e+ e ++v++++ + FUN_002335-T1 327 RSLGDFRKAIEYHEKHLEIAKEVCDRVGE 355 567799*******************9965 PP == domain 8 score: 7.5 bits; conditional E-value: 0.0087 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkkard 67 + +s + ++A+e +e+ e ++v++++ + sLgn +++ d FUN_002335-T1 365 AYQSLGDFRKAIEYHEKHLEIAKEVCDRVGEgnaYGSLGNAYRSLGD 411 678899***********************553336789999988666 PP == domain 9 score: 7.4 bits; conditional E-value: 0.0093 WH_Halo_primase 26 hsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 s + ++A+e +e+ e ++v++++ + sLgn +++ d r+ FUN_002335-T1 407 RSLGDFRKAIEYHEKHLEIAKEVCDRVGEgnaYGSLGNAYRSLGDFRK 454 577899*********************553336789999988877766 PP == domain 10 score: 3.5 bits; conditional E-value: 0.15 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhr 69 s + ++A+e +e+ e ++v +++ sLgn +++ d r FUN_002335-T1 447 RSLGDFRKAIEYHEKHLEIAKEVSDRVgegGAYGSLGNAYQSLGDFR 493 577899*********************54444789999999887766 PP == domain 11 score: 7.1 bits; conditional E-value: 0.011 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkard 67 + +s + ++A+e +e+ e ++v++++ sLgn +++ d FUN_002335-T1 485 AYQSLGDFRKAIEYHEKHLEIAKEVCDRVgegGAYGSLGNAYQSLGD 531 678899***********************544447899999998766 PP == domain 12 score: 5.2 bits; conditional E-value: 0.045 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + +s + ++A+e +e+ e ++v +++ sLgn +++ d r+ FUN_002335-T1 525 AYQSLGDFRKAIEYHEKHLEIAKEVSDRVgegGAYGSLGNAYQSLGDFRK 574 6788999**********************544448899999999888776 PP == domain 13 score: -1.6 bits; conditional E-value: 5.9 WH_Halo_primase 22 lgefhsarelydAleaYepere.we 45 l++f a+e ++Al + + ++ w+ FUN_002335-T1 656 LDKFVYAVEAFNALRSFLKSEDeWK 680 7899999999999999865444487 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 3.5 2.6e+03 3 24 .. 13 34 .. 12 35 .. 0.79 2 ? 3.3 0.1 0.23 1.7e+02 3 24 .. 53 74 .. 52 78 .. 0.89 3 ? 2.8 0.0 0.33 2.5e+02 3 24 .. 93 114 .. 92 115 .. 0.87 4 ? 2.8 0.0 0.33 2.5e+02 3 24 .. 133 154 .. 132 155 .. 0.87 5 ? 3.4 0.0 0.21 1.6e+02 2 24 .. 172 194 .. 171 195 .. 0.88 6 ? 4.7 0.0 0.081 61 2 24 .. 238 260 .. 237 261 .. 0.91 7 ? 4.7 0.0 0.081 61 2 24 .. 278 300 .. 277 301 .. 0.91 8 ? 5.9 0.0 0.034 25 3 24 .. 319 340 .. 318 341 .. 0.91 9 ? 1.0 0.0 1.2 8.8e+02 8 24 .. 364 380 .. 358 381 .. 0.85 10 ? 5.9 0.0 0.034 25 3 24 .. 399 420 .. 398 421 .. 0.91 11 ? 5.9 0.0 0.034 25 3 24 .. 439 460 .. 438 461 .. 0.91 12 ? 4.7 0.0 0.081 61 2 24 .. 478 500 .. 477 501 .. 0.91 13 ? 4.7 0.0 0.081 61 2 24 .. 518 540 .. 517 541 .. 0.91 14 ? 5.1 0.0 0.06 45 2 25 .. 558 581 .. 557 584 .. 0.91 15 ? 6.9 0.0 0.016 12 3 25 .. 599 621 .. 598 621 .. 0.91 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 3.5 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++ + G++++A+++++ FUN_002335-T1 13 YQNLAYAFQSLGDFRKAIKYHE 34 55666778889*******9987 PP == domain 2 score: 3.3 bits; conditional E-value: 0.23 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+++ + FUN_002335-T1 53 YGSLGNAYQSLGDFRKAIDYCE 74 99999*************9876 PP == domain 3 score: 2.8 bits; conditional E-value: 0.33 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002335-T1 93 YGNLGNAYQSLGDFRKAIEYHE 114 777889*************987 PP == domain 4 score: 2.8 bits; conditional E-value: 0.33 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002335-T1 133 YGNLGNAYQSLGDFRKAIEYHE 154 777889*************987 PP == domain 5 score: 3.4 bits; conditional E-value: 0.21 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002335-T1 172 AYGNLGNAYQSLGDFRKAIEYHE 194 6888999*************987 PP == domain 6 score: 4.7 bits; conditional E-value: 0.081 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHE 260 599999**************987 PP == domain 7 score: 4.7 bits; conditional E-value: 0.081 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHE 300 599999**************987 PP == domain 8 score: 5.9 bits; conditional E-value: 0.034 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002335-T1 319 YGSLGNAYRSLGDFRKAIEYHE 340 99999**************987 PP == domain 9 score: 1.0 bits; conditional E-value: 1.2 PPR 8 sgycknGkleeAlelfk 24 ++y + G++++A+e+++ FUN_002335-T1 364 NAYQSLGDFRKAIEYHE 380 78999*********987 PP == domain 10 score: 5.9 bits; conditional E-value: 0.034 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002335-T1 399 YGSLGNAYRSLGDFRKAIEYHE 420 99999**************987 PP == domain 11 score: 5.9 bits; conditional E-value: 0.034 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002335-T1 439 YGSLGNAYRSLGDFRKAIEYHE 460 99999**************987 PP == domain 12 score: 4.7 bits; conditional E-value: 0.081 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHE 500 599999**************987 PP == domain 13 score: 4.7 bits; conditional E-value: 0.081 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002335-T1 518 AYGSLGNAYQSLGDFRKAIEYHE 540 599999**************987 PP == domain 14 score: 5.1 bits; conditional E-value: 0.06 PPR 2 tynslIsgycknGkleeAlelfke 25 +y sl ++y + G++++A+e++++ FUN_002335-T1 558 AYGSLGNAYQSLGDFRKAIEYHEK 581 599999**************9886 PP == domain 15 score: 6.9 bits; conditional E-value: 0.016 PPR 3 ynslIsgycknGkleeAlelfke 25 y sl +y+ G++++A+el+++ FUN_002335-T1 599 YGSLGIAYSLLGDVQKAIELYEK 621 888889***************86 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.1 0.1 0.0034 2.6 3 60 .. 16 79 .. 15 82 .. 0.85 2 ? 2.7 0.0 0.35 2.6e+02 3 19 .. 96 112 .. 88 121 .. 0.82 3 ? 4.6 0.2 0.086 65 3 53 .. 136 192 .. 135 200 .. 0.59 4 ? 2.1 0.0 0.52 3.9e+02 3 19 .. 242 258 .. 237 266 .. 0.90 5 ? 6.0 0.3 0.031 24 3 57 .. 282 342 .. 281 347 .. 0.74 6 ? 5.9 0.3 0.033 25 4 58 .. 363 423 .. 355 428 .. 0.70 7 ? 6.7 0.3 0.019 15 3 58 .. 402 463 .. 401 468 .. 0.77 8 ? 2.1 0.0 0.54 4e+02 3 19 .. 482 498 .. 481 504 .. 0.91 9 ? 2.0 0.0 0.55 4.2e+02 3 19 .. 522 538 .. 521 543 .. 0.91 10 ! 14.8 0.0 5.4e-05 0.041 3 60 .. 562 625 .. 561 628 .. 0.87 11 ? -0.5 0.0 3.5 2.6e+03 7 27 .. 646 666 .. 641 676 .. 0.75 12 ? 0.1 0.2 2.2 1.6e+03 5 26 .. 696 717 .. 696 730 .. 0.80 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0034 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalra 60 la a+ +gd++ A+++ l+ a++++ A+ lG a+ +g++ +A+++++++l++ FUN_002335-T1 16 LAYAFQSLGDFRKAIKYhekhLKIAIEAGhrVGEGNAYGSLGNAYQSLGDFRKAIDYCEKYLKI 79 788999999999998654444888899989977999************************9976 PP == domain 2 score: 2.7 bits; conditional E-value: 0.35 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002335-T1 96 LGNAYQSLGDFRKAIEY 112 68888888888888875 PP == domain 3 score: 4.6 bits; conditional E-value: 0.086 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ e l+ A+ +lG a+ +g++ +A+++ FUN_002335-T1 136 LGNAYQSLGDFRKAIEYHEKHLEIAkevsdrVGEGSAYGNLGNAYQSLGDFRKAIEY 192 677777777777777765444443344455544556666666666666666666655 PP == domain 4 score: 2.1 bits; conditional E-value: 0.52 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002335-T1 242 LGNAYQSLGDFRKAIEY 258 7999999*****99986 PP == domain 5 score: 6.0 bits; conditional E-value: 0.031 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraa 57 l++a+ +gd++ A+++ e l+ A+ lG a+ +g++ +A+++ ++ FUN_002335-T1 282 LGNAYQSLGDFRKAIEYHEKHLEIAkevcdrVGEGNAYGSLGNAYRSLGDFRKAIEYHEKH 342 6788888888888888876666655677777557788888888888888888888876655 PP == domain 6 score: 5.9 bits; conditional E-value: 0.033 TPR_16 4 araalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 ++a+ +gd++ A+++ e l+ A+ lG a+ +g++ +A+++ ++ l FUN_002335-T1 363 GNAYQSLGDFRKAIEYHEKHLEIAkevcdrVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHL 423 6666667777777766655555446777775577888889999999999988888766655 PP == domain 7 score: 6.7 bits; conditional E-value: 0.019 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd++ A+++ e l+ A+ lG a+ +g++ +A+++ ++ l FUN_002335-T1 402 LGNAYRSLGDFRKAIEYHEKHLEIAkevcdrVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHL 463 68899999999999988876666666788886678899999999999999999998866665 PP == domain 8 score: 2.1 bits; conditional E-value: 0.54 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002335-T1 482 LGNAYQSLGDFRKAIEY 498 799***********986 PP == domain 9 score: 2.0 bits; conditional E-value: 0.55 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002335-T1 522 LGNAYQSLGDFRKAIEY 538 799***********986 PP == domain 10 score: 14.8 bits; conditional E-value: 5.4e-05 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalra 60 l++a+ +gd++ A+++ e l+ A+ lG a+ +g++++A+++y++ l++ FUN_002335-T1 562 LGNAYQSLGDFRKAIEYHEKYLKIAievgdrVGEGNAYGSLGIAYSLLGDVQKAIELYEKHLEI 625 799***********988666666666666**7799************************99976 PP == domain 11 score: -0.5 bits; conditional E-value: 3.5 TPR_16 7 alaagdyddAaaaleaalrrn 27 ++ +g+++ A+ + a++++ FUN_002335-T1 646 YFSLGQFENALDKFVYAVEAF 666 677788888888887777776 PP == domain 12 score: 0.1 bits; conditional E-value: 2.2 TPR_16 5 raalaagdyddAaaaleaalrr 26 r++l+ g++++A+ a+e+ +++ FUN_002335-T1 696 RSLLRIGKFREALFAAETGRAQ 717 68999*******9877776665 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.1 8e+02 13 31 .. 19 37 .. 13 41 .. 0.83 2 ? -0.8 0.0 3.2 2.4e+03 14 29 .. 60 75 .. 59 79 .. 0.83 3 ? 1.5 0.0 0.63 4.7e+02 14 31 .. 100 117 .. 96 120 .. 0.89 4 ? 1.4 0.0 0.64 4.8e+02 14 31 .. 140 157 .. 137 160 .. 0.89 5 ? 1.4 0.0 0.64 4.8e+02 14 31 .. 180 197 .. 177 200 .. 0.89 6 ? 1.4 0.0 0.65 4.9e+02 14 31 .. 246 263 .. 244 266 .. 0.89 7 ? 1.4 0.0 0.65 4.9e+02 14 31 .. 286 303 .. 284 306 .. 0.89 8 ? 1.1 0.0 0.78 5.9e+02 14 31 .. 326 343 .. 324 346 .. 0.88 9 ? 1.4 0.0 0.65 4.9e+02 14 31 .. 366 383 .. 364 386 .. 0.89 10 ? 1.1 0.0 0.78 5.9e+02 14 31 .. 406 423 .. 404 426 .. 0.88 11 ? 1.1 0.0 0.78 5.9e+02 14 31 .. 446 463 .. 444 466 .. 0.88 12 ? 1.4 0.0 0.65 4.9e+02 14 31 .. 486 503 .. 484 506 .. 0.89 13 ? 1.4 0.0 0.65 4.9e+02 14 31 .. 526 543 .. 524 546 .. 0.89 14 ? 0.8 0.0 1 7.5e+02 14 31 .. 566 583 .. 564 586 .. 0.87 15 ? 0.0 0.0 1.7 1.3e+03 14 25 .. 646 657 .. 643 674 .. 0.85 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.1 DUF2977 13 sYvlvGgledgidvdednl 31 + G ++++i ++e+ l FUN_002335-T1 19 AFQSLGDFRKAIKYHEKHL 37 67789***********987 PP == domain 2 score: -0.8 bits; conditional E-value: 3.2 DUF2977 14 YvlvGgledgidvded 29 Y G ++++id+ e+ FUN_002335-T1 60 YQSLGDFRKAIDYCEK 75 7789********9876 PP == domain 3 score: 1.5 bits; conditional E-value: 0.63 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 100 YQSLGDFRKAIEYHEKHL 117 7889***********987 PP == domain 4 score: 1.4 bits; conditional E-value: 0.64 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 140 YQSLGDFRKAIEYHEKHL 157 7889***********987 PP == domain 5 score: 1.4 bits; conditional E-value: 0.64 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 180 YQSLGDFRKAIEYHEKHL 197 7889***********987 PP == domain 6 score: 1.4 bits; conditional E-value: 0.65 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 246 YQSLGDFRKAIEYHEKHL 263 7889***********987 PP == domain 7 score: 1.4 bits; conditional E-value: 0.65 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 286 YQSLGDFRKAIEYHEKHL 303 7889***********987 PP == domain 8 score: 1.1 bits; conditional E-value: 0.78 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 326 YRSLGDFRKAIEYHEKHL 343 7789***********987 PP == domain 9 score: 1.4 bits; conditional E-value: 0.65 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 366 YQSLGDFRKAIEYHEKHL 383 7889***********987 PP == domain 10 score: 1.1 bits; conditional E-value: 0.78 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 406 YRSLGDFRKAIEYHEKHL 423 7789***********987 PP == domain 11 score: 1.1 bits; conditional E-value: 0.78 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 446 YRSLGDFRKAIEYHEKHL 463 7789***********987 PP == domain 12 score: 1.4 bits; conditional E-value: 0.65 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 486 YQSLGDFRKAIEYHEKHL 503 7889***********987 PP == domain 13 score: 1.4 bits; conditional E-value: 0.65 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 526 YQSLGDFRKAIEYHEKHL 543 7889***********987 PP == domain 14 score: 0.8 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002335-T1 566 YQSLGDFRKAIEYHEKYL 583 7889**********9866 PP == domain 15 score: 0.0 bits; conditional E-value: 1.7 DUF2977 14 YvlvGgledgid 25 Y G++e+++d FUN_002335-T1 646 YFSLGQFENALD 657 7789*******9 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.56 4.2e+02 219 244 .. 14 39 .. 5 43 .. 0.86 2 ? 0.9 0.0 0.47 3.5e+02 219 244 .. 54 79 .. 49 82 .. 0.88 3 ? 2.6 0.0 0.14 1e+02 219 246 .. 94 121 .. 90 123 .. 0.88 4 ? 2.6 0.0 0.14 1.1e+02 220 246 .. 135 161 .. 132 165 .. 0.88 5 ? 2.8 0.0 0.13 95 219 246 .. 174 201 .. 169 203 .. 0.88 6 ? 2.3 0.0 0.17 1.3e+02 219 244 .. 240 265 .. 237 270 .. 0.88 7 ? 3.0 0.0 0.11 82 219 246 .. 280 307 .. 277 310 .. 0.89 8 ? 2.6 0.0 0.14 1.1e+02 219 246 .. 320 347 .. 316 349 .. 0.88 9 ? 0.8 0.0 0.5 3.8e+02 222 246 .. 363 387 .. 357 390 .. 0.86 10 ? 2.7 0.0 0.14 1e+02 219 246 .. 400 427 .. 396 430 .. 0.88 11 ? 2.7 0.0 0.14 1e+02 219 246 .. 440 467 .. 436 470 .. 0.88 12 ? 2.9 0.0 0.11 86 219 246 .. 480 507 .. 477 509 .. 0.88 13 ? 3.0 0.0 0.11 83 219 246 .. 520 547 .. 517 550 .. 0.89 14 ? 2.0 0.0 0.22 1.7e+02 219 244 .. 560 585 .. 557 588 .. 0.88 15 ? 3.4 0.0 0.084 63 219 246 .. 600 627 .. 596 629 .. 0.88 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.56 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + +A A+ lg+ rkA +y +k+++ FUN_002335-T1 14 QNLAYAFQSLGDFRKAIKYHEKHLKI 39 678999****************9875 PP == domain 2 score: 0.9 bits; conditional E-value: 0.47 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA y +k+++ FUN_002335-T1 54 GSLGNAYQSLGDFRKAIDYCEKYLKI 79 67899****************99875 PP == domain 3 score: 2.6 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 94 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 121 56899*****************998765 PP == domain 4 score: 2.6 bits; conditional E-value: 0.14 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqnk 246 ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 135 NLGNAYQSLGDFRKAIEYHEKHLEIAK 161 6899*****************988766 PP == domain 5 score: 2.8 bits; conditional E-value: 0.13 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 174 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 201 67899*****************998765 PP == domain 6 score: 2.3 bits; conditional E-value: 0.17 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002335-T1 240 GSLGNAYQSLGDFRKAIEYHEKHLEI 265 57899*****************9876 PP == domain 7 score: 3.0 bits; conditional E-value: 0.11 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 280 GSLGNAYQSLGDFRKAIEYHEKHLEIAK 307 57899*****************998766 PP == domain 8 score: 2.6 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 320 GSLGNAYRSLGDFRKAIEYHEKHLEIAK 347 67899*****************998765 PP == domain 9 score: 0.8 bits; conditional E-value: 0.5 TPR_15 222 AaAllllgqnrkALpyfrkkaaqnk 246 + A+ lg+ rkA +y +k+++ +k FUN_002335-T1 363 GNAYQSLGDFRKAIEYHEKHLEIAK 387 569****************998766 PP == domain 10 score: 2.7 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 400 GSLGNAYRSLGDFRKAIEYHEKHLEIAK 427 67899*****************998766 PP == domain 11 score: 2.7 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 440 GSLGNAYRSLGDFRKAIEYHEKHLEIAK 467 67899*****************998766 PP == domain 12 score: 2.9 bits; conditional E-value: 0.11 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 480 GSLGNAYQSLGDFRKAIEYHEKHLEIAK 507 57899*****************998765 PP == domain 13 score: 3.0 bits; conditional E-value: 0.11 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002335-T1 520 GSLGNAYQSLGDFRKAIEYHEKHLEIAK 547 57899*****************998766 PP == domain 14 score: 2.0 bits; conditional E-value: 0.22 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002335-T1 560 GSLGNAYQSLGDFRKAIEYHEKYLKI 585 57899****************99875 PP == domain 15 score: 3.4 bits; conditional E-value: 0.084 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A++llg+ +kA + ++k+++ +k FUN_002335-T1 600 GSLGIAYSLLGDVQKAIELYEKHLEIAK 627 56889*****************998766 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.95 7.1e+02 82 111 .. 45 74 .. 27 79 .. 0.74 2 ? -1.3 0.0 4.7 3.6e+03 87 106 .. 90 109 .. 74 112 .. 0.63 3 ? 1.5 0.0 0.64 4.8e+02 75 107 .. 118 150 .. 101 152 .. 0.83 4 ? 2.7 0.0 0.28 2.1e+02 75 107 .. 158 190 .. 148 192 .. 0.85 5 ? 3.4 0.0 0.17 1.3e+02 75 107 .. 224 256 .. 209 258 .. 0.87 6 ? 3.7 0.0 0.13 98 75 107 .. 264 296 .. 256 298 .. 0.88 7 ? 4.4 0.0 0.08 60 75 107 .. 304 336 .. 296 378 .. 0.84 8 ? 4.3 0.0 0.084 63 75 107 .. 384 416 .. 374 420 .. 0.88 9 ? 4.1 0.0 0.1 76 75 107 .. 424 456 .. 417 458 .. 0.89 10 ? 4.0 0.0 0.11 80 75 107 .. 464 496 .. 457 498 .. 0.89 11 ? 3.3 0.0 0.17 1.3e+02 75 107 .. 504 536 .. 497 538 .. 0.88 12 ? 4.1 0.0 0.1 76 75 107 .. 544 576 .. 536 578 .. 0.88 13 ? 1.1 0.0 0.86 6.5e+02 53 91 .. 1050 1088 .. 1042 1100 .. 0.71 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.95 GGDEF_2 82 rrlggitvriGvGrpveglaglrrSyreAr 111 +r+g+ +++ +G+++++l ++r++ ++ FUN_002335-T1 45 HRVGEGNAYGSLGNAYQSLGDFRKAIDYCE 74 455556778889999999999999876555 PP == domain 2 score: -1.3 bits; conditional E-value: 4.7 GGDEF_2 87 itvriGvGrpveglaglrrS 106 +++ +G+++++l ++r++ FUN_002335-T1 90 GNAYGNLGNAYQSLGDFRKA 109 44444467777777777776 PP == domain 3 score: 1.5 bits; conditional E-value: 0.64 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ ++ +G+++++l ++r++ FUN_002335-T1 118 EIAKEVCDRVGEGGAYGNLGNAYQSLGDFRKAI 150 8999999999999999999**********9985 PP == domain 4 score: 2.7 bits; conditional E-value: 0.28 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002335-T1 158 EIAKEVSDRVGEGSAYGNLGNAYQSLGDFRKAI 190 899999999999999999***********9985 PP == domain 5 score: 3.4 bits; conditional E-value: 0.17 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ ++ +G+++++l ++r++ FUN_002335-T1 224 EIAKEVCDRVGEGGAYGSLGNAYQSLGDFRKAI 256 8999999999999*****************986 PP == domain 6 score: 3.7 bits; conditional E-value: 0.13 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ ++ +G+++++l ++r++ FUN_002335-T1 264 EIANEVSDRVGEGGAYGSLGNAYQSLGDFRKAI 296 89999*************************986 PP == domain 7 score: 4.4 bits; conditional E-value: 0.08 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ +++ +G+++++l ++r++ FUN_002335-T1 304 EIAKEVCDRVGEGNAYGSLGNAYRSLGDFRKAI 336 788888888888999999999999999998875 PP == domain 8 score: 4.3 bits; conditional E-value: 0.084 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ +++ +G+++++l ++r++ FUN_002335-T1 384 EIAKEVCDRVGEGNAYGSLGNAYRSLGDFRKAI 416 8999**************************986 PP == domain 9 score: 4.1 bits; conditional E-value: 0.1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ +++ +G+++++l ++r++ FUN_002335-T1 424 EIAKEVCDRVGEGNAYGSLGNAYRSLGDFRKAI 456 89999*************************986 PP == domain 10 score: 4.0 bits; conditional E-value: 0.11 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ ++ +G+++++l ++r++ FUN_002335-T1 464 EIAKEVSDRVGEGGAYGSLGNAYQSLGDFRKAI 496 8999**************************986 PP == domain 11 score: 3.3 bits; conditional E-value: 0.17 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ ++ +G+++++l ++r++ FUN_002335-T1 504 EIAKEVCDRVGEGGAYGSLGNAYQSLGDFRKAI 536 8999999***********************986 PP == domain 12 score: 4.1 bits; conditional E-value: 0.1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ ++ +G+++++l ++r++ FUN_002335-T1 544 EIAKEVSDRVGEGGAYGSLGNAYQSLGDFRKAI 576 8999**************************986 PP == domain 13 score: 1.1 bits; conditional E-value: 0.86 GGDEF_2 53 lvavrgdrlvlllpvddeadaeellerlrrrlgg.itvri 91 ++a ++ lv+l+++ddea+ e+++r+ ++l++ t+++ FUN_002335-T1 1050 MAAGARSVLVALWALDDEAT-MEFMKRFYQHLKEgKTASA 1088 5566677899*******864.6788888888877444444 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.1 1.8 1.3e+03 14 28 .. 25 39 .. 18 46 .. 0.85 2 ? 1.7 0.0 0.53 4e+02 5 28 .. 56 79 .. 54 84 .. 0.89 3 ? 3.6 0.0 0.13 1e+02 5 29 .. 96 120 .. 94 124 .. 0.88 4 ? 3.8 0.0 0.11 86 5 30 .. 136 161 .. 134 166 .. 0.88 5 ? 3.7 0.0 0.13 95 5 29 .. 176 200 .. 174 206 .. 0.88 6 ? 3.6 0.0 0.13 1e+02 5 30 .. 242 267 .. 240 272 .. 0.88 7 ? 3.4 0.0 0.15 1.1e+02 5 29 .. 282 306 .. 280 310 .. 0.88 8 ? 2.3 0.0 0.35 2.6e+02 5 29 .. 322 346 .. 320 350 .. 0.86 9 ? 2.1 0.0 0.39 3e+02 6 29 .. 363 386 .. 361 390 .. 0.87 10 ? 2.3 0.0 0.35 2.6e+02 5 29 .. 402 426 .. 400 430 .. 0.86 11 ? 2.5 0.0 0.3 2.2e+02 5 30 .. 442 467 .. 440 472 .. 0.86 12 ? 3.4 0.0 0.15 1.1e+02 5 29 .. 482 506 .. 480 510 .. 0.88 13 ? 3.7 0.0 0.13 97 5 30 .. 522 547 .. 520 552 .. 0.88 14 ? 3.7 0.1 0.12 93 5 28 .. 562 585 .. 560 590 .. 0.90 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 1.8 ARM_TT21_4th 14 qYkkAinYYeaalks 28 +++kAi+Y e+ lk+ FUN_002335-T1 25 DFRKAIKYHEKHLKI 39 799*******99986 PP == domain 2 score: 1.7 bits; conditional E-value: 0.53 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ lk+ FUN_002335-T1 56 LGNAYQSLGDFRKAIDYCEKYLKI 79 799**************9998886 PP == domain 3 score: 3.6 bits; conditional E-value: 0.13 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002335-T1 96 LGNAYQSLGDFRKAIEYHEKHLEIA 120 799****************998765 PP == domain 4 score: 3.8 bits; conditional E-value: 0.11 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002335-T1 136 LGNAYQSLGDFRKAIEYHEKHLEIAK 161 799****************9988765 PP == domain 5 score: 3.7 bits; conditional E-value: 0.13 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002335-T1 176 LGNAYQSLGDFRKAIEYHEKHLEIA 200 799****************998765 PP == domain 6 score: 3.6 bits; conditional E-value: 0.13 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002335-T1 242 LGNAYQSLGDFRKAIEYHEKHLEIAN 267 799****************9988765 PP == domain 7 score: 3.4 bits; conditional E-value: 0.15 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002335-T1 282 LGNAYQSLGDFRKAIEYHEKHLEIA 306 799****************998765 PP == domain 8 score: 2.3 bits; conditional E-value: 0.35 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002335-T1 322 LGNAYRSLGDFRKAIEYHEKHLEIA 346 699999999**********988765 PP == domain 9 score: 2.1 bits; conditional E-value: 0.39 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalkss 29 G+a+ +++kAi+Y e+ l++ FUN_002335-T1 363 GNAYQSLGDFRKAIEYHEKHLEIA 386 88999999**********998765 PP == domain 10 score: 2.3 bits; conditional E-value: 0.35 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002335-T1 402 LGNAYRSLGDFRKAIEYHEKHLEIA 426 699999999**********988765 PP == domain 11 score: 2.5 bits; conditional E-value: 0.3 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002335-T1 442 LGNAYRSLGDFRKAIEYHEKHLEIAK 467 699999999**********9988765 PP == domain 12 score: 3.4 bits; conditional E-value: 0.15 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002335-T1 482 LGNAYQSLGDFRKAIEYHEKHLEIA 506 799****************998765 PP == domain 13 score: 3.7 bits; conditional E-value: 0.13 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002335-T1 522 LGNAYQSLGDFRKAIEYHEKHLEIAK 547 799****************9988765 PP == domain 14 score: 3.7 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ lk+ FUN_002335-T1 562 LGNAYQSLGDFRKAIEYHEKYLKI 585 799****************99986 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.1 0.17 1.3e+02 75 167 .. 73 116 .. 8 132 .. 0.58 2 ? 4.9 0.0 0.028 21 102 172 .. 133 201 .. 111 206 .. 0.67 3 ? 4.1 0.0 0.05 37 101 172 .. 238 307 .. 214 310 .. 0.77 4 ? 5.2 0.0 0.022 17 101 173 .. 278 348 .. 245 355 .. 0.75 5 ? 3.2 0.0 0.094 71 99 172 .. 316 387 .. 295 393 .. 0.70 6 ? 3.1 0.0 0.097 73 101 172 .. 358 427 .. 338 432 .. 0.67 7 ! 7.1 0.1 0.0058 4.3 100 174 .. 397 469 .. 375 508 .. 0.63 8 ! 7.0 0.1 0.0065 4.9 100 174 .. 437 509 .. 413 552 .. 0.64 9 ? 5.2 0.1 0.023 17 101 173 .. 478 548 .. 452 585 .. 0.69 10 ? 3.2 0.0 0.092 69 76 167 .. 540 582 .. 509 631 .. 0.61 11 ? 2.7 0.0 0.13 98 101 170 .. 598 665 .. 587 671 .. 0.71 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.17 TPR_NPHP3 75 akaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqa 167 ++Yl+ + ++ + v++ + +L + y+ g f++a +++++ FUN_002335-T1 73 CEKYLKIAIEVGHRVGEGNAYG-------------------------------------------------NLGNAYQSLGDFRKAIEYHEKH 116 2334444444444444444444.................................................4444444444444444444444 PP == domain 2 score: 4.9 bits; conditional E-value: 0.028 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 y lG+ + lg +a++ ++ Lei + D ++++ +L + y+ g f++a +++++ lei + FUN_002335-T1 133 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 201 5566666666666666666666677766555..45555566777777777777777777777777777765 PP == domain 3 score: 4.1 bits; conditional E-value: 0.05 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 y +lG+ + lg +a++ ++ Lei + + D + ++ L + y+ g f++a +++++ lei + FUN_002335-T1 238 AYGSLGNAYQSLGDFRKAIEYHEKHLEIANEV--SDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAK 307 57777888888888888888888888888777..45666677888899999999999999999998888876 PP == domain 4 score: 5.2 bits; conditional E-value: 0.022 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 y +lG+ + lg +a++ ++ Lei + D ++++ L + y g f++a +++++ lei ++ FUN_002335-T1 278 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 348 57778888888888888888888888888777..456666788888999999999999999999999988765 PP == domain 5 score: 3.2 bits; conditional E-value: 0.094 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 + y +lG+ + lg +a++ ++ Lei + D ++++ + y+ g f++a +++++ lei + FUN_002335-T1 316 GNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVC--DRVGEGNAYGSRGNAYQSLGDFRKAIEYHEKHLEIAK 387 45688888888888888888888888888877774..4445566666677777777777777777777777765 PP == domain 6 score: 3.1 bits; conditional E-value: 0.097 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 y + G+ + lg +a++ ++ Lei + D ++++ L + y g f++a +++++ lei + FUN_002335-T1 358 AYGSRGNAYQSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAK 427 56666666666666666666677777776666..34555566777777777777777777777777777765 PP == domain 7 score: 7.1 bits; conditional E-value: 0.0058 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 + y +lG+ + lg +a++ ++ Lei + D ++++ L + y g f++a +++++ lei ++ FUN_002335-T1 397 NAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV--CDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV 469 567777777777777777777777777776666..3455556677777777777777777777777777776553 PP == domain 8 score: 7.0 bits; conditional E-value: 0.0065 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 + y +lG+ + lg +a++ ++ Lei + D + ++ L + y+ g f++a +++++ lei ++ FUN_002335-T1 437 NAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV 509 567777777777777777777777777776666..4555566677777777777777777777777777777654 PP == domain 9 score: 5.2 bits; conditional E-value: 0.023 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 y +lG+ + lg +a++ ++ Lei + D + ++ L + y+ g f++a +++++ lei ++ FUN_002335-T1 478 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVC--DRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 548 466666666666666667777777777766663..45555667777888888888888888888888877665 PP == domain 10 score: 3.2 bits; conditional E-value: 0.092 TPR_NPHP3 76 kaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqa 167 +++l+ +k++ d v++ ++ + y++lG f k + ++ FUN_002335-T1 540 EKHLEIAKEVSDRVGEGGAYGSLGNAYQSLGDFRKAIEYH-------------------------------------------------EKY 582 4455555666666655555666666666666666555443.................................................333 PP == domain 11 score: 2.7 bits; conditional E-value: 0.13 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 y +lG lg +++a++ ++ Lei + d + ++h++ g y g+f++a + + a+e FUN_002335-T1 598 AYGSLGIAYSLLGDVQKAIELYEKHLEIAKEVGDRK--GEGIAYHNMGGEYFSLGQFENALDKFVYAVEA 665 577777777777777788887788888777774444..44445788888888888888887777777765 PP >> Mre11_C_bact Mre11 C-terminal domain, bacteria # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.1 3.8 2.9e+03 26 35 .. 31 40 .. 26 44 .. 0.79 2 ? 3.5 0.0 0.14 1e+02 22 42 .. 107 127 .. 105 132 .. 0.86 3 ? 2.8 0.0 0.22 1.6e+02 22 42 .. 147 167 .. 145 172 .. 0.85 4 ? 3.8 0.1 0.11 82 22 43 .. 187 208 .. 185 212 .. 0.84 5 ? 3.5 0.0 0.13 97 22 42 .. 253 273 .. 251 278 .. 0.86 6 ? 3.8 0.1 0.11 82 22 43 .. 293 314 .. 291 318 .. 0.84 7 ? 3.8 0.1 0.11 82 22 43 .. 333 354 .. 331 358 .. 0.84 8 ? 3.8 0.1 0.11 82 22 43 .. 373 394 .. 371 398 .. 0.84 9 ? 3.8 0.1 0.11 82 22 43 .. 413 434 .. 411 438 .. 0.84 10 ? 2.7 0.0 0.23 1.8e+02 22 42 .. 453 473 .. 451 478 .. 0.85 11 ? 3.5 0.0 0.14 1e+02 22 42 .. 493 513 .. 491 518 .. 0.86 12 ? 2.7 0.0 0.23 1.8e+02 22 42 .. 533 553 .. 531 558 .. 0.85 13 ? 5.1 0.0 0.043 33 22 43 .. 573 594 .. 571 598 .. 0.82 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 3.8 Mre11_C_bact 26 enhekLLkiL 35 hek Lki FUN_002335-T1 31 KYHEKHLKIA 40 57******95 PP == domain 2 score: 3.5 bits; conditional E-value: 0.14 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002335-T1 107 RKAIEYHEKHLEIAKEVCDRV 127 577799***********9998 PP == domain 3 score: 2.8 bits; conditional E-value: 0.22 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002335-T1 147 RKAIEYHEKHLEIAKEVSDRV 167 577799**********99988 PP == domain 4 score: 3.8 bits; conditional E-value: 0.11 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek L i e+ D v FUN_002335-T1 187 RKAIEYHEKHLEIAKEVCDRVG 208 577799*************986 PP == domain 5 score: 3.5 bits; conditional E-value: 0.13 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i +e+ D v FUN_002335-T1 253 RKAIEYHEKHLEIANEVSDRV 273 577799***********9988 PP == domain 6 score: 3.8 bits; conditional E-value: 0.11 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek L i e+ D v FUN_002335-T1 293 RKAIEYHEKHLEIAKEVCDRVG 314 577799*************986 PP == domain 7 score: 3.8 bits; conditional E-value: 0.11 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek L i e+ D v FUN_002335-T1 333 RKAIEYHEKHLEIAKEVCDRVG 354 577799*************986 PP == domain 8 score: 3.8 bits; conditional E-value: 0.11 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek L i e+ D v FUN_002335-T1 373 RKAIEYHEKHLEIAKEVCDRVG 394 577799*************986 PP == domain 9 score: 3.8 bits; conditional E-value: 0.11 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek L i e+ D v FUN_002335-T1 413 RKAIEYHEKHLEIAKEVCDRVG 434 577799*************986 PP == domain 10 score: 2.7 bits; conditional E-value: 0.23 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002335-T1 453 RKAIEYHEKHLEIAKEVSDRV 473 577799**********99988 PP == domain 11 score: 3.5 bits; conditional E-value: 0.14 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002335-T1 493 RKAIEYHEKHLEIAKEVCDRV 513 577799***********9998 PP == domain 12 score: 2.7 bits; conditional E-value: 0.23 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002335-T1 533 RKAIEYHEKHLEIAKEVSDRV 553 577799**********99988 PP == domain 13 score: 5.1 bits; conditional E-value: 0.043 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek Lki e+ D v FUN_002335-T1 573 RKAIEYHEKYLKIAIEVGDRVG 594 577799*******999988875 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.1 79 70 141 .. 36 115 .. 21 124 .. 0.71 2 ! 11.3 0.1 0.00018 0.13 85 253 .. 98 264 .. 87 270 .. 0.85 3 ! 5.5 0.9 0.0098 7.4 87 248 .. 286 459 .. 262 469 .. 0.48 4 ! 5.8 0.3 0.0081 6.1 85 248 .. 364 539 .. 353 542 .. 0.53 5 ? 2.8 0.0 0.065 49 71 141 .. 543 621 .. 541 632 .. 0.73 6 ? 2.5 0.0 0.083 62 409 450 .. 642 683 .. 617 688 .. 0.65 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.1 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaekkdrihlr........ktyynyakhleakgdieeaiklyek 141 +L++ ea + + + + y l + yq+ g + ka++ +ek+ +i + ++y n + ++ gd+++ai+++ek FUN_002335-T1 36 HLKIAIEAGHRVGEGNAYGSLGNAYQSLGDFRKAIDYCEKYLKIAIEvghrvgegNAYGNLGNAYQSLGDFRKAIEYHEK 115 56777778888888888888888888888888888888776555443111111116777778888888888888887776 PP == domain 2 score: 11.3 bits; conditional E-value: 0.00018 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddteaLesyvkkskdkelkkWw 176 + y+ l ++ +a + +k le+a++ +dr+ +y n + ++ gd+++ai+++ek + e+ + + d + +y + + + + FUN_002335-T1 98 NAYQSLGDFRKAIEYHEKHLEIAKEvCDRVGEGGAYGNLGNAYQSLGDFRKAIEYHEK----HLEIAKEVSDRVGEGSAYGNLGNAYQSLGDF 186 568888888888888999999997647**************************99998....5677777778888888888887777777778 PP TPR_IF140-IFT172 177 aqylestg.eletalkyyeaaedylslvrvlCyledlekaaelanetgdkaacyhlarqyenadeikeaihfftraqa 253 + +e+++ +le a+++ ++ ++ + + + le a+e+++ g+ a l+ y++ +++++ai+++ + FUN_002335-T1 187 RKAIEYHEkHLEIAKEVCDRVGEGNAYGSLGNAYQSLEIAKEVCDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLE 264 8888876427999*******9999999999999999***********************************9987655 PP == domain 3 score: 5.5 bits; conditional E-value: 0.0098 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddt...eaLesyvkkskdkelkkW 175 y+ l ++ +a + +k le+a++ +dr+ ++y + + gd+++ai+++ek ev + + + ++ ++y + + ++ + FUN_002335-T1 286 YQSLGDFRKAIEYHEKHLEIAKEvCDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVCDRVGEGNaygSRGNAYQSLGDFRKAIEY 378 444444444444444445566443577777777777777777777777777777764444444433222222011122333333333333444 PP TPR_IF140-IFT172 176 waqylestgel....etalkyyeaaedylslv..r..vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihff 248 ++le ++e+ + y + + y sl r + + ++le a+e+++ g+ a l+ y + +++++ai+++ FUN_002335-T1 379 HEKHLEIAKEVcdrvGEGNAYGSLGNAYRSLGdfRkaIEYHEKHLEIAKEVCDRVGEGNAYGSLGNAYRSLGDFRKAIEYH 459 444444433331111122222222333333321111122223334455555555555566666677777777777776665 PP == domain 4 score: 5.8 bits; conditional E-value: 0.0081 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aL.esyvkkskdkelk 173 + y+ l ++ +a + +k le+a++ +dr+ ++y + + gd+++ai+++ek ev + + ++ +L ++y + + ++ FUN_002335-T1 364 NAYQSLGDFRKAIEYHEKHLEIAKEvCDRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVCDRVGEGNAygSLgNAYRSLGDFRKAI 456 566777777777777777777776535777777777777777777777777777777765555555544433332113323344444445555 PP TPR_IF140-IFT172 174 kWwaqylestgeletal....kyyeaaedylslv..r..vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihff 248 + ++le ++e+ y + + y sl r + + ++le a+e+++ g+ a l+ y++ +++++ai+++ FUN_002335-T1 457 EYHEKHLEIAKEVSDRVgeggAYGSLGNAYQSLGdfRkaIEYHEKHLEIAKEVCDRVGEGGAYGSLGNAYQSLGDFRKAIEYH 539 55556665555554322111122233333444431121122333345556666666666666666666666666666666665 PP == domain 5 score: 2.8 bits; conditional E-value: 0.065 TPR_IF140-IFT172 71 Lglldeaekllksckrydllnklyqasgkwdkalevaekk........drihlrktyynyakhleakgdieeaiklyek 141 L++ +e + + + + y l + yq+ g + ka+e ek+ dr+ ++y gd+++ai+lyek FUN_002335-T1 543 LEIAKEVSDRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKYlkiaievgDRVGEGNAYGSLGIAYSLLGDVQKAIELYEK 621 6777777777777888888888888888888888766654222233337777788888888888999999999999998 PP == domain 6 score: 2.5 bits; conditional E-value: 0.083 TPR_IF140-IFT172 409 vaevclkqenyhlatkkftqaGdkvkamkaLlksGdtekiif 450 ++ ++ ++++ a kf a + ++a++++lks d ki f FUN_002335-T1 642 MGGEYFSLGQFENALDKFVYAVEAFNALRSFLKSEDEWKINF 683 444455567788888888888888888888888888777766 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 2.7 2e+03 32 55 .. 13 36 .. 11 46 .. 0.79 2 ? 4.7 0.0 0.06 45 36 59 .. 57 80 .. 52 86 .. 0.88 3 ? 2.2 0.0 0.35 2.6e+02 33 59 .. 94 120 .. 91 126 .. 0.82 4 ? 2.8 0.0 0.22 1.7e+02 33 60 .. 134 161 .. 131 167 .. 0.81 5 ? 2.5 0.0 0.29 2.2e+02 32 59 .. 173 200 .. 169 206 .. 0.81 6 ? 1.8 0.0 0.45 3.4e+02 35 60 .. 242 267 .. 237 273 .. 0.81 7 ? 1.3 0.0 0.69 5.2e+02 35 59 .. 282 306 .. 277 312 .. 0.81 8 ? -1.5 0.0 5.2 3.9e+03 36 58 .. 323 345 .. 319 352 .. 0.77 9 ? 3.8 0.0 0.11 84 34 59 .. 361 386 .. 357 393 .. 0.83 10 ? -1.5 0.0 5.2 3.9e+03 36 58 .. 403 425 .. 399 432 .. 0.77 11 ? -0.9 0.0 3.3 2.5e+03 36 60 .. 443 467 .. 438 473 .. 0.77 12 ? 1.3 0.0 0.69 5.2e+02 35 59 .. 482 506 .. 477 512 .. 0.81 13 ? 1.8 0.0 0.47 3.5e+02 35 60 .. 522 547 .. 517 553 .. 0.81 14 ? 4.5 0.0 0.065 49 35 59 .. 562 586 .. 557 592 .. 0.87 15 ? 3.1 0.0 0.18 1.4e+02 35 61 .. 602 628 .. 597 633 .. 0.85 16 ? -2.0 0.0 7.4 5.5e+03 39 56 .. 646 663 .. 642 665 .. 0.84 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 2.7 TPR_9 32 rrdrGllyaqlgcleaAladLeay 55 +++ + + + lg++ +A+++ e+ FUN_002335-T1 13 YQNLAYAFQSLGDFRKAIKYHEKH 36 56789999*********9876655 PP == domain 2 score: 4.7 bits; conditional E-value: 0.06 TPR_9 36 GllyaqlgcleaAladLeaylala 59 G +y+ lg++ +A+++ e+yl++a FUN_002335-T1 57 GNAYQSLGDFRKAIDYCEKYLKIA 80 789*****************9765 PP == domain 3 score: 2.2 bits; conditional E-value: 0.35 TPR_9 33 rdrGllyaqlgcleaAladLeaylala 59 + G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 94 GNLGNAYQSLGDFRKAIEYHEKHLEIA 120 567999***********9987777665 PP == domain 4 score: 2.8 bits; conditional E-value: 0.22 TPR_9 33 rdrGllyaqlgcleaAladLeaylalap 60 + G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 134 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 161 578999************9888887775 PP == domain 5 score: 2.5 bits; conditional E-value: 0.29 TPR_9 32 rrdrGllyaqlgcleaAladLeaylala 59 + + G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 173 YGNLGNAYQSLGDFRKAIEYHEKHLEIA 200 5678999***********9877777665 PP == domain 6 score: 1.8 bits; conditional E-value: 0.45 TPR_9 35 rGllyaqlgcleaAladLeaylalap 60 G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 242 LGNAYQSLGDFRKAIEYHEKHLEIAN 267 5789***********99888887775 PP == domain 7 score: 1.3 bits; conditional E-value: 0.69 TPR_9 35 rGllyaqlgcleaAladLeaylala 59 G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 282 LGNAYQSLGDFRKAIEYHEKHLEIA 306 57899**********9877777665 PP == domain 8 score: -1.5 bits; conditional E-value: 5.2 TPR_9 36 GllyaqlgcleaAladLeaylal 58 G +y lg++ +A+++ e+ l++ FUN_002335-T1 323 GNAYRSLGDFRKAIEYHEKHLEI 345 66788899999999987776665 PP == domain 9 score: 3.8 bits; conditional E-value: 0.11 TPR_9 34 drGllyaqlgcleaAladLeaylala 59 rG +y+ lg++ +A+++ e+ l++a FUN_002335-T1 361 SRGNAYQSLGDFRKAIEYHEKHLEIA 386 59**************9988777665 PP == domain 10 score: -1.5 bits; conditional E-value: 5.2 TPR_9 36 GllyaqlgcleaAladLeaylal 58 G +y lg++ +A+++ e+ l++ FUN_002335-T1 403 GNAYRSLGDFRKAIEYHEKHLEI 425 66788899999999987776665 PP == domain 11 score: -0.9 bits; conditional E-value: 3.3 TPR_9 36 GllyaqlgcleaAladLeaylalap 60 G +y lg++ +A+++ e+ l++a FUN_002335-T1 443 GNAYRSLGDFRKAIEYHEKHLEIAK 467 6678899999999998888777765 PP == domain 12 score: 1.3 bits; conditional E-value: 0.69 TPR_9 35 rGllyaqlgcleaAladLeaylala 59 G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 482 LGNAYQSLGDFRKAIEYHEKHLEIA 506 57899**********9877777665 PP == domain 13 score: 1.8 bits; conditional E-value: 0.47 TPR_9 35 rGllyaqlgcleaAladLeaylalap 60 G +y+ lg++ +A+++ e+ l++a FUN_002335-T1 522 LGNAYQSLGDFRKAIEYHEKHLEIAK 547 5789***********99888887765 PP == domain 14 score: 4.5 bits; conditional E-value: 0.065 TPR_9 35 rGllyaqlgcleaAladLeaylala 59 G +y+ lg++ +A+++ e+yl++a FUN_002335-T1 562 LGNAYQSLGDFRKAIEYHEKYLKIA 586 5789*****************9865 PP == domain 15 score: 3.1 bits; conditional E-value: 0.18 TPR_9 35 rGllyaqlgcleaAladLeaylalapd 61 G++y lg++++A++ e+ l++a + FUN_002335-T1 602 LGIAYSLLGDVQKAIELYEKHLEIAKE 628 69**************99999988765 PP == domain 16 score: -2.0 bits; conditional E-value: 7.4 TPR_9 39 yaqlgcleaAladLeayl 56 y+ lg++e Al+ + +++ FUN_002335-T1 646 YFSLGQFENALDKFVYAV 663 789********9987765 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 3 2.3e+03 71 89 .. 25 43 .. 12 52 .. 0.83 2 ? -2.1 0.0 8.2 6.2e+03 71 88 .. 65 82 .. 58 87 .. 0.78 3 ? 2.5 0.0 0.3 2.2e+02 71 92 .. 105 126 .. 97 135 .. 0.87 4 ? 2.0 0.0 0.45 3.4e+02 71 92 .. 145 166 .. 137 182 .. 0.87 5 ? 3.7 0.0 0.13 98 71 93 .. 185 211 .. 177 244 .. 0.74 6 ? 1.8 0.0 0.5 3.7e+02 71 91 .. 251 271 .. 243 277 .. 0.86 7 ? 2.6 0.0 0.28 2.1e+02 71 92 .. 291 312 .. 284 321 .. 0.87 8 ? 2.4 0.0 0.33 2.5e+02 71 92 .. 331 352 .. 325 364 .. 0.88 9 ? 2.8 0.0 0.26 1.9e+02 71 92 .. 371 392 .. 361 405 .. 0.87 10 ? 3.2 0.2 0.18 1.4e+02 71 92 .. 411 432 .. 404 478 .. 0.64 11 ? 2.7 0.0 0.27 2.1e+02 70 92 .. 490 512 .. 478 524 .. 0.88 12 ? 1.6 0.0 0.57 4.2e+02 71 91 .. 531 551 .. 524 556 .. 0.85 13 ? -1.1 0.0 4.1 3.1e+03 71 88 .. 571 588 .. 561 595 .. 0.83 14 ? 1.7 0.0 0.53 4e+02 71 95 .. 611 635 .. 607 642 .. 0.86 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 3 DUF7018 71 llekaidhyekslklieea 89 ++ kai+++ek lk++ ea FUN_002335-T1 25 DFRKAIKYHEKHLKIAIEA 43 8999999999999988776 PP == domain 2 score: -2.1 bits; conditional E-value: 8.2 DUF7018 71 llekaidhyekslkliee 88 ++ kaid+ ek lk++ e FUN_002335-T1 65 DFRKAIDYCEKYLKIAIE 82 789999999999988755 PP == domain 3 score: 2.5 bits; conditional E-value: 0.3 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 105 DFRKAIEYHEKHLEIAKEVCDR 126 89****************9876 PP == domain 4 score: 2.0 bits; conditional E-value: 0.45 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 145 DFRKAIEYHEKHLEIAKEVSDR 166 899*************998765 PP == domain 5 score: 3.7 bits; conditional E-value: 0.13 DUF7018 71 llekaidhyekslklieeavek....k 93 ++ kai+++ek l++++e+ ++ + FUN_002335-T1 185 DFRKAIEYHEKHLEIAKEVCDRvgegN 211 89****************999855551 PP == domain 6 score: 1.8 bits; conditional E-value: 0.5 DUF7018 71 llekaidhyekslklieeave 91 ++ kai+++ek l++++e+ + FUN_002335-T1 251 DFRKAIEYHEKHLEIANEVSD 271 89**************99866 PP == domain 7 score: 2.6 bits; conditional E-value: 0.28 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 291 DFRKAIEYHEKHLEIAKEVCDR 312 89****************9876 PP == domain 8 score: 2.4 bits; conditional E-value: 0.33 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 331 DFRKAIEYHEKHLEIAKEVCDR 352 899***************9877 PP == domain 9 score: 2.8 bits; conditional E-value: 0.26 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 371 DFRKAIEYHEKHLEIAKEVCDR 392 89****************9877 PP == domain 10 score: 3.2 bits; conditional E-value: 0.18 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 411 DFRKAIEYHEKHLEIAKEVCDR 432 5666666666666666666555 PP == domain 11 score: 2.7 bits; conditional E-value: 0.27 DUF7018 70 kllekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002335-T1 490 GDFRKAIEYHEKHLEIAKEVCDR 512 489****************9876 PP == domain 12 score: 1.6 bits; conditional E-value: 0.57 DUF7018 71 llekaidhyekslklieeave 91 ++ kai+++ek l++++e+ + FUN_002335-T1 531 DFRKAIEYHEKHLEIAKEVSD 551 899*************99866 PP == domain 13 score: -1.1 bits; conditional E-value: 4.1 DUF7018 71 llekaidhyekslkliee 88 ++ kai+++ek lk++ e FUN_002335-T1 571 DFRKAIEYHEKYLKIAIE 588 899********9998766 PP == domain 14 score: 1.7 bits; conditional E-value: 0.53 DUF7018 71 llekaidhyekslklieeavekkdk 95 +++kai+ yek l++++e+ ++k + FUN_002335-T1 611 DVQKAIELYEKHLEIAKEVGDRKGE 635 799***************9888766 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.28 2.1e+02 5 52 .. 24 77 .. 20 80 .. 0.69 2 ? 5.9 0.0 0.031 23 5 47 .. 64 112 .. 60 127 .. 0.82 3 ? 6.1 0.1 0.027 20 5 46 .. 104 151 .. 100 162 .. 0.90 4 ? 5.5 0.0 0.04 30 5 46 .. 144 191 .. 140 202 .. 0.88 5 ? 4.2 0.0 0.11 79 5 47 .. 250 298 .. 246 313 .. 0.88 6 ? 3.3 0.0 0.2 1.5e+02 5 46 .. 290 337 .. 286 353 .. 0.87 7 ? 3.2 0.0 0.22 1.6e+02 5 46 .. 370 417 .. 366 428 .. 0.87 8 ? 3.6 0.0 0.16 1.2e+02 4 47 .. 409 458 .. 406 473 .. 0.86 9 ? 4.1 0.0 0.11 83 4 47 .. 449 498 .. 446 513 .. 0.87 10 ? 3.8 0.0 0.14 1.1e+02 5 47 .. 490 538 .. 486 553 .. 0.87 11 ? 3.8 0.0 0.13 1e+02 5 47 .. 530 578 .. 526 588 .. 0.86 12 ? 4.3 0.1 0.093 70 5 54 .. 570 625 .. 566 629 .. 0.77 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.28 TPR_19 5 gdydeAlalLeqalae..dPd....naearllLArallalgrldeAealLaalp 52 gd+ +A+++ e+ l++ + + a+ L++a+ lg++ +A+ ++++ FUN_002335-T1 24 GDFRKAIKYHEKHLKIaiEAGhrvgEGNAYGSLGNAYQSLGDFRKAIDYCEKYL 77 677777777777333322333355578889999999999999999998877765 PP == domain 2 score: 5.9 bits; conditional E-value: 0.031 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+ ++e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002335-T1 64 GDFRKAIDYCEKYLKIAIEvghrvgEGNAYGNLGNAYQSLGDFRKAIEY 112 899999999999998844444455599*******************985 PP == domain 3 score: 6.1 bits; conditional E-value: 0.027 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002335-T1 104 GDFRKAIEYHEKHLEIAKEvcdrvgEGGAYGNLGNAYQSLGDFRKAIE 151 9999999999999999999999999*********************97 PP == domain 4 score: 5.5 bits; conditional E-value: 0.04 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002335-T1 144 GDFRKAIEYHEKHLEIAKEvsdrvgEGSAYGNLGNAYQSLGDFRKAIE 191 99999999999999998888888889999*****************97 PP == domain 5 score: 4.2 bits; conditional E-value: 0.11 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++++ a+ L++a+ lg++ +A++ FUN_002335-T1 250 GDFRKAIEYHEKHLEIANEvsdrvgEGGAYGSLGNAYQSLGDFRKAIEY 298 9999999999999999999888999999999**************9975 PP == domain 6 score: 3.3 bits; conditional E-value: 0.2 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002335-T1 290 GDFRKAIEYHEKHLEIAKEvcdrvgEGNAYGSLGNAYRSLGDFRKAIE 337 89999999999999999988888889999999999******9999987 PP == domain 7 score: 3.2 bits; conditional E-value: 0.22 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002335-T1 370 GDFRKAIEYHEKHLEIAKEvcdrvgEGNAYGSLGNAYRSLGDFRKAIE 417 899999999999999999888888899999999999*99999999987 PP == domain 8 score: 3.6 bits; conditional E-value: 0.16 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002335-T1 409 LGDFRKAIEYHEKHLEIAKEvcdrvgEGNAYGSLGNAYRSLGDFRKAIEY 458 6999999999999999999999999999999999*********9999875 PP == domain 9 score: 4.1 bits; conditional E-value: 0.11 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002335-T1 449 LGDFRKAIEYHEKHLEIAKEvsdrvgEGGAYGSLGNAYQSLGDFRKAIEY 498 69999999999999999888888888999999**************9975 PP == domain 10 score: 3.8 bits; conditional E-value: 0.14 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002335-T1 490 GDFRKAIEYHEKHLEIAKEvcdrvgEGGAYGSLGNAYQSLGDFRKAIEY 538 89999999999999999988888889999999*************9975 PP == domain 11 score: 3.8 bits; conditional E-value: 0.13 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002335-T1 530 GDFRKAIEYHEKHLEIAKEvsdrvgEGGAYGSLGNAYQSLGDFRKAIEY 578 89999999999999988888888889999999***********999875 PP == domain 12 score: 4.3 bits; conditional E-value: 0.093 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaalpaa 54 gd+ +A+++ e+ l+++ + a+ L+ a+ lg++ +A++l ++ ++ FUN_002335-T1 570 GDFRKAIEYHEKYLKIAIEvgdrvgEGNAYGSLGIAYSLLGDVQKAIELYEKHLEI 625 88888888888888773333344458899999999999999999999999887765 PP >> Foie-gras_1 Foie gras liver health family 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 0.67 5e+02 24 51 .. 104 131 .. 98 143 .. 0.81 2 ? 0.4 0.0 0.76 5.7e+02 23 51 .. 143 171 .. 137 183 .. 0.81 3 ? 1.3 0.0 0.43 3.2e+02 24 51 .. 184 211 .. 178 223 .. 0.84 4 ? -1.9 0.0 3.9 2.9e+03 180 212 .. 225 258 .. 212 268 .. 0.81 5 ? 1.1 0.0 0.49 3.7e+02 24 51 .. 290 317 .. 284 325 .. 0.84 6 ? 1.2 0.0 0.45 3.4e+02 24 51 .. 330 357 .. 323 369 .. 0.84 7 ? 1.0 0.0 0.5 3.8e+02 23 51 .. 369 397 .. 363 404 .. 0.85 8 ? 1.0 0.0 0.53 4e+02 24 51 .. 410 437 .. 404 446 .. 0.85 9 ? -1.0 0.0 2.1 1.6e+03 24 51 .. 450 477 .. 444 488 .. 0.81 10 ? 0.3 0.0 0.82 6.1e+02 24 51 .. 490 517 .. 484 529 .. 0.83 11 ? -0.5 0.0 1.4 1.1e+03 24 51 .. 530 557 .. 524 580 .. 0.73 12 ! 7.4 0.0 0.0058 4.4 167 214 .. 613 660 .. 592 670 .. 0.82 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.67 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g FUN_002335-T1 104 GDFRKAIEYHEKHLEIAKEVCDRVGEGG 131 66789***************99988775 PP == domain 2 score: 0.4 bits; conditional E-value: 0.76 Foie-gras_1 23 tgqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g+ FUN_002335-T1 143 LGDFRKAIEYHEKHLEIAKEVSDRVGEGS 171 566789***************99988887 PP == domain 3 score: 1.3 bits; conditional E-value: 0.43 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g+ FUN_002335-T1 184 GDFRKAIEYHEKHLEIAKEVCDRVGEGN 211 66789******************98887 PP == domain 4 score: -1.9 bits; conditional E-value: 3.9 Foie-gras_1 180 FskrkqtRlaeelsl.eiAeEylrlgdwakalel 212 +k ++R+ e ++ ++++y lgd+ ka+e FUN_002335-T1 225 IAKEVCDRVGEGGAYgSLGNAYQSLGDFRKAIEY 258 4566789999999887899999999999999985 PP == domain 5 score: 1.1 bits; conditional E-value: 0.49 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g+ FUN_002335-T1 290 GDFRKAIEYHEKHLEIAKEVCDRVGEGN 317 66789******************88887 PP == domain 6 score: 1.2 bits; conditional E-value: 0.45 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g+ FUN_002335-T1 330 GDFRKAIEYHEKHLEIAKEVCDRVGEGN 357 66789******************88887 PP == domain 7 score: 1.0 bits; conditional E-value: 0.5 Foie-gras_1 23 tgqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g+ FUN_002335-T1 369 LGDFRKAIEYHEKHLEIAKEVCDRVGEGN 397 567789******************88887 PP == domain 8 score: 1.0 bits; conditional E-value: 0.53 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g+ FUN_002335-T1 410 GDFRKAIEYHEKHLEIAKEVCDRVGEGN 437 66789******************88887 PP == domain 9 score: -1.0 bits; conditional E-value: 2.1 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g FUN_002335-T1 450 GDFRKAIEYHEKHLEIAKEVSDRVGEGG 477 66789**********9999988877664 PP == domain 10 score: 0.3 bits; conditional E-value: 0.82 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g FUN_002335-T1 490 GDFRKAIEYHEKHLEIAKEVCDRVGEGG 517 66789***************99988775 PP == domain 11 score: -0.5 bits; conditional E-value: 1.4 Foie-gras_1 24 gqpseAvrkfrkHrervkdvvgrrgkgt 51 g ++A++ ++kH+e k+v +r g+g FUN_002335-T1 530 GDFRKAIEYHEKHLEIAKEVSDRVGEGG 557 5667888889999888888877766654 PP == domain 12 score: 7.4 bits; conditional E-value: 0.0058 Foie-gras_1 167 kliidlLkraleeFskrkqtRlaeelsl.eiAeEylrlgdwakalellr 214 + +i+l+++ le +++ +R+ e +++ +++ Ey+ lg++++al+ + FUN_002335-T1 613 QKAIELYEKHLEIAKEV-GDRKGEGIAYhNMGGEYFSLGQFENALDKFV 660 67899999999888855.56777777776***************98765 PP >> Sec1 Sec1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 1.8 1.3e+03 300 332 .. 10 42 .. 4 53 .. 0.85 2 ? 1.1 0.0 0.32 2.4e+02 301 338 .. 91 128 .. 64 133 .. 0.78 3 ? 2.5 0.0 0.12 87 306 339 .. 136 169 .. 129 203 .. 0.74 4 ? 2.1 0.0 0.16 1.2e+02 299 339 .. 165 209 .. 147 223 .. 0.76 5 ? 1.0 0.0 0.34 2.6e+02 306 338 .. 242 274 .. 238 277 .. 0.89 6 ? 0.4 0.0 0.53 3.9e+02 305 339 .. 281 315 .. 254 322 .. 0.81 7 ? 0.2 0.0 0.59 4.4e+02 303 338 .. 319 354 .. 292 358 .. 0.78 8 ? 0.7 0.0 0.41 3.1e+02 302 337 .. 398 433 .. 363 437 .. 0.58 9 ? 1.6 0.0 0.23 1.7e+02 304 338 .. 440 474 .. 413 478 .. 0.80 10 ? 0.2 0.0 0.59 4.5e+02 304 338 .. 480 514 .. 453 517 .. 0.77 11 ? 1.7 0.0 0.21 1.5e+02 306 339 .. 522 555 .. 494 581 .. 0.88 12 ? -2.2 0.0 3.1 2.4e+03 311 333 .. 607 629 .. 572 633 .. 0.84 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 1.8 Sec1 300 sesiadlkdfvekLpelqeekkklslHtnlaee 332 ++s ++l + ++L+++++ k ++H+++a e FUN_002335-T1 10 EKSYQNLAYAFQSLGDFRKAIKYHEKHLKIAIE 42 45899999**********************966 PP == domain 2 score: 1.1 bits; conditional E-value: 0.32 Sec1 301 esiadlkdfvekLpelqeekkklslHtnlaeellkiik 338 + +l ++ ++L+++++ + ++H+++a e+ +++ FUN_002335-T1 91 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVCDRVG 128 5667889999**********************988875 PP == domain 3 score: 2.5 bits; conditional E-value: 0.12 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ ++L+++++ + ++H+++a e+++++ + FUN_002335-T1 136 LGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGE 169 6677889999999999999999999999998876 PP == domain 4 score: 2.1 bits; conditional E-value: 0.16 Sec1 299 s....sesiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 + + +l ++ ++L+++++ + ++H+++a e+ +++ + FUN_002335-T1 165 DrvgeGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVCDRVGE 209 2445456678899999**********************9988865 PP == domain 5 score: 1.0 bits; conditional E-value: 0.34 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkiik 338 l ++ ++L+++++ + ++H+++a e+++++ FUN_002335-T1 242 LGNAYQSLGDFRKAIEYHEKHLEIANEVSDRVG 274 5678899*********************99986 PP == domain 6 score: 0.4 bits; conditional E-value: 0.53 Sec1 305 dlkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ ++L+++++ + ++H+++a e+ +++ + FUN_002335-T1 281 SLGNAYQSLGDFRKAIEYHEKHLEIAKEVCDRVGE 315 57788999********************9988765 PP == domain 7 score: 0.2 bits; conditional E-value: 0.59 Sec1 303 iadlkdfvekLpelqeekkklslHtnlaeellkiik 338 l ++ ++L+++++ + ++H+++a e+ +++ FUN_002335-T1 319 YGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVCDRVG 354 5667889999********************988876 PP == domain 8 score: 0.7 bits; conditional E-value: 0.41 Sec1 302 siadlkdfvekLpelqeekkklslHtnlaeellkii 337 l ++ ++L+++++ + ++H+++a e+ +++ FUN_002335-T1 398 AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVCDRV 433 344555666777777777777777777777766655 PP == domain 9 score: 1.6 bits; conditional E-value: 0.23 Sec1 304 adlkdfvekLpelqeekkklslHtnlaeellkiik 338 l ++ ++L+++++ + ++H+++a e+++++ FUN_002335-T1 440 GSLGNAYRSLGDFRKAIEYHEKHLEIAKEVSDRVG 474 66788999**********************99986 PP == domain 10 score: 0.2 bits; conditional E-value: 0.59 Sec1 304 adlkdfvekLpelqeekkklslHtnlaeellkiik 338 l ++ ++L+++++ + ++H+++a e+ +++ FUN_002335-T1 480 GSLGNAYQSLGDFRKAIEYHEKHLEIAKEVCDRVG 514 567789999*******************9988775 PP == domain 11 score: 1.7 bits; conditional E-value: 0.21 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ ++L+++++ + ++H+++a e+++++ + FUN_002335-T1 522 LGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGE 555 6788899**********************99876 PP == domain 12 score: -2.2 bits; conditional E-value: 3.1 Sec1 311 ekLpelqeekkklslHtnlaeel 333 + L++ q+ + +++H+++a e+ FUN_002335-T1 607 SLLGDVQKAIELYEKHLEIAKEV 629 669999**************986 PP >> DUF6944 Family of unknown function (DUF6944) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 0.069 52 83 113 .. 86 116 .. 7 162 .. 0.54 2 ! 8.1 0.3 0.0028 2.1 59 163 .. 133 251 .. 95 255 .. 0.70 3 ! 7.6 0.5 0.0039 3 61 163 .. 175 251 .. 135 291 .. 0.51 4 ! 8.1 0.3 0.0027 2 39 116 .. 177 265 .. 167 335 .. 0.51 5 ? 3.0 0.0 0.11 80 89 113 .. 358 382 .. 281 450 .. 0.56 6 ? 1.5 0.0 0.29 2.2e+02 94 94 .. 427 427 .. 362 504 .. 0.52 7 ? 3.5 0.1 0.07 53 93 141 .. 482 533 .. 433 575 .. 0.56 8 ? 3.3 0.1 0.084 63 92 116 .. 521 545 .. 479 603 .. 0.53 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.069 DUF6944 83 eeeeglrleilGnllQalGaavsavdeleee 113 eg+ lGn Q+lG + +a++ e++ FUN_002335-T1 86 RVGEGNAYGNLGNAYQSLGDFRKAIEYHEKH 116 2223333334444444444444444444443 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0028 DUF6944 59 leklGneiqaiGnltvvvgllldl.........eeeeglrleilGnllQalGaavsavdeleeeeee.eellnii..GnllqaiGnslqaiggike 142 + +lGn+ q+ G + ++ + + eg lGn Q+lG + +a++ e++ e +e+ + + Gn+ ++Gn+ q++ ke FUN_002335-T1 133 YGNLGNAYQSLGDFRKAIEYHEKHleiakevsdRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIaKEVCDRVgeGNAYGSLGNAYQSLEIAKE 228 556666667777666666655433333333322222334446789999999999999999998888755666665336899999999999999999 PP DUF6944 143 lkek..egealnaiGswiqaiGa 163 + ++ eg a +G+ q +G FUN_002335-T1 229 VCDRvgEGGAYGSLGNAYQSLGD 251 99998888899999999998885 PP == domain 3 score: 7.6 bits; conditional E-value: 0.0039 DUF6944 61 klGneiqaiGnltvvvgllldleeeeglrleilGnllQalGaavsavdeleeeeee.eellnii..GnllqaiGnslqaiggikelkek..egeal 151 +l Gn Q+lG + +a++ e++ e +e+ + + Gn+ ++Gn+ q++ ke+ ++ eg a FUN_002335-T1 175 NL-------------------------------GNAYQSLGDFRKAIEYHEKHLEIaKEVCDRVgeGNAYGSLGNAYQSLEIAKEVCDRvgEGGAY 239 33...............................444444444444444444444432333333311344444444444444444444444444444 PP DUF6944 152 naiGswiqaiGa 163 +G+ q +G FUN_002335-T1 240 GSLGNAYQSLGD 251 444444444442 PP == domain 4 score: 8.1 bits; conditional E-value: 0.0027 DUF6944 39 GnvlqatGnaLqadgeeeeslekl.........GneiqaiGnltvvvgllldl..eeeeglrleilGnllQalGaavsavdeleeeeee 116 Gn+ q++G++ a++ e++le + Gn+ + Gn+ ++ ++ ++ eg lGn Q+lG + +a++ e++ e FUN_002335-T1 177 GNAYQSLGDFRKAIEYHEKHLEIAkevcdrvgeGNAYGSLGNAYQSLEIAKEVcdRVGEGGAYGSLGNAYQSLGDFRKAIEYHEKHLEI 265 44444444444444444422222222222223344455555555555555544333334444455555555555555544444444433 PP == domain 5 score: 3.0 bits; conditional E-value: 0.11 DUF6944 89 rleilGnllQalGaavsavdeleee 113 Gn Q+lG + +a++ e++ FUN_002335-T1 358 AYGSRGNAYQSLGDFRKAIEYHEKH 382 2333455555555555555544444 PP == domain 6 score: 1.5 bits; conditional E-value: 0.29 DUF6944 94 G 94 FUN_002335-T1 427 K 427 0 PP == domain 7 score: 3.5 bits; conditional E-value: 0.07 DUF6944 93 lGnllQalGaavsavdeleeeeee.eellniiGn..llqaiGnslqaiggik 141 lGn Q+lG + +a++ e++ e +e+ + +G+ + ++Gn+ q++g ++ FUN_002335-T1 482 LGNAYQSLGDFRKAIEYHEKHLEIaKEVCDRVGEggAYGSLGNAYQSLGDFR 533 4555555555554444444444432333333322113333444444443333 PP == domain 8 score: 3.3 bits; conditional E-value: 0.084 DUF6944 92 ilGnllQalGaavsavdeleeeeee 116 lGn Q+lG + +a++ e++ e FUN_002335-T1 521 SLGNAYQSLGDFRKAIEYHEKHLEI 545 2344444444444444433333333 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.0 0.33 2.5e+02 30 68 .. 53 91 .. 51 95 .. 0.86 2 ? -0.5 0.0 2.5 1.8e+03 30 57 .. 93 120 .. 89 152 .. 0.67 3 ? -0.0 0.0 1.7 1.3e+03 30 64 .. 133 167 .. 129 192 .. 0.73 4 ? -0.6 0.0 2.6 1.9e+03 30 58 .. 173 201 .. 169 222 .. 0.71 5 ? -0.3 0.0 2.2 1.6e+03 30 60 .. 239 269 .. 238 298 .. 0.74 6 ? -0.7 0.0 2.9 2.2e+03 30 59 .. 279 308 .. 277 327 .. 0.77 7 ? -0.9 0.0 3.4 2.5e+03 30 59 .. 319 348 .. 316 379 .. 0.72 8 ? -1.3 0.0 4.4 3.3e+03 30 59 .. 359 388 .. 356 406 .. 0.78 9 ? -1.1 0.0 3.7 2.7e+03 30 58 .. 399 427 .. 394 448 .. 0.75 10 ? -1.1 0.0 3.7 2.7e+03 30 59 .. 439 468 .. 435 479 .. 0.75 11 ? -0.5 0.0 2.4 1.8e+03 30 58 .. 479 507 .. 474 538 .. 0.72 12 ? -0.6 0.0 2.7 2e+03 30 59 .. 519 548 .. 516 559 .. 0.77 13 ? 1.1 0.0 0.77 5.8e+02 30 68 .. 559 597 .. 557 599 .. 0.84 14 ? 1.8 0.0 0.45 3.4e+02 30 69 .. 599 638 .. 597 643 .. 0.87 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.33 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGm 68 y+ +G++ + Lgd +++++ ++++lk + ++ + G FUN_002335-T1 53 YGSLGNAYQSLGDFRKAIDYCEKYLKIAIEVGHRVGEGN 91 78899********************99988887776665 PP == domain 2 score: -0.5 bits; conditional E-value: 2.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkee 57 y+ +G++ + Lgd +++++ ++ l+ FUN_002335-T1 93 YGNLGNAYQSLGDFRKAIEYHEKHLEIA 120 5556667777777777777666655544 PP == domain 3 score: -0.0 bits; conditional E-value: 1.7 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekal 64 y+ +G++ + Lgd +++++ ++ l+ ++ + + FUN_002335-T1 133 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRV 167 56678888888888888888888777666644444 PP == domain 4 score: -0.6 bits; conditional E-value: 2.6 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeel 58 y+ +G++ + Lgd +++++ ++ l+ + FUN_002335-T1 173 YGNLGNAYQSLGDFRKAIEYHEKHLEIAK 201 56677888888888888887777665544 PP == domain 5 score: -0.3 bits; conditional E-value: 2.2 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkL 60 y+ +G++ + Lgd +++++ ++ l+ ++ FUN_002335-T1 239 YGSLGNAYQSLGDFRKAIEYHEKHLEIANEV 269 6778888999999999998888877666554 PP == domain 6 score: -0.7 bits; conditional E-value: 2.9 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G++ + Lgd +++++ ++ l+ ++ FUN_002335-T1 279 YGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 308 677899999999999999988887765555 PP == domain 7 score: -0.9 bits; conditional E-value: 3.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G++ + Lgd +++++ ++ l+ ++ FUN_002335-T1 319 YGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 348 667788888888888888877776665544 PP == domain 8 score: -1.3 bits; conditional E-value: 4.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ G++ + Lgd +++++ ++ l+ ++ FUN_002335-T1 359 YGSRGNAYQSLGDFRKAIEYHEKHLEIAKE 388 677899999999999999998887765555 PP == domain 9 score: -1.1 bits; conditional E-value: 3.7 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeel 58 y+ +G++ + Lgd +++++ ++ l+ + FUN_002335-T1 399 YGSLGNAYRSLGDFRKAIEYHEKHLEIAK 427 67788888889999988888887776555 PP == domain 10 score: -1.1 bits; conditional E-value: 3.7 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G++ + Lgd +++++ ++ l+ ++ FUN_002335-T1 439 YGSLGNAYRSLGDFRKAIEYHEKHLEIAKE 468 677888899999999999888887766555 PP == domain 11 score: -0.5 bits; conditional E-value: 2.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeel 58 y+ +G++ + Lgd +++++ ++ l+ + FUN_002335-T1 479 YGSLGNAYQSLGDFRKAIEYHEKHLEIAK 507 66778888888888888887777666544 PP == domain 12 score: -0.6 bits; conditional E-value: 2.7 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G++ + Lgd +++++ ++ l+ ++ FUN_002335-T1 519 YGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 548 677899999999999999998888776655 PP == domain 13 score: 1.1 bits; conditional E-value: 0.77 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGm 68 y+ +G++ + Lgd +++++ +++lk + ++ + G FUN_002335-T1 559 YGSLGNAYQSLGDFRKAIEYHEKYLKIAIEVGDRVGEGN 597 77899999************9999998888887776665 PP == domain 14 score: 1.8 bits; conditional E-value: 0.45 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G + + Lgd++++++ +++ l+ ++ ++ G+a FUN_002335-T1 599 YGSLGIAYSLLGDVQKAIELYEKHLEIAKEVGDRKGEGIA 638 6778999999************999999999998888877 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.7 0.1 0.17 1.3e+02 38 72 .. 12 46 .. 8 48 .. 0.89 2 ? 3.1 0.0 0.12 93 38 72 .. 52 86 .. 50 88 .. 0.89 3 ? 2.5 0.1 0.19 1.4e+02 38 64 .. 92 118 .. 90 123 .. 0.89 4 ? 2.2 0.0 0.24 1.8e+02 38 64 .. 132 158 .. 131 167 .. 0.87 5 ? 2.5 0.1 0.2 1.5e+02 38 64 .. 172 198 .. 160 203 .. 0.90 6 ? 0.9 0.0 0.59 4.4e+02 39 64 .. 239 264 .. 237 274 .. 0.87 7 ? 1.0 0.0 0.57 4.3e+02 39 64 .. 279 304 .. 275 313 .. 0.88 8 ? 1.0 0.1 0.55 4.1e+02 38 64 .. 318 344 .. 315 350 .. 0.88 9 ? 0.2 0.0 0.99 7.4e+02 38 64 .. 358 384 .. 356 391 .. 0.86 10 ? 1.3 0.1 0.46 3.5e+02 38 64 .. 398 424 .. 380 430 .. 0.88 11 ? 1.4 0.0 0.44 3.3e+02 38 64 .. 438 464 .. 435 474 .. 0.86 12 ? 0.9 0.0 0.61 4.6e+02 39 64 .. 479 504 .. 475 509 .. 0.87 13 ? 1.1 0.0 0.52 3.9e+02 39 64 .. 519 544 .. 517 553 .. 0.85 14 ? 5.2 0.2 0.028 21 39 144 .. 559 667 .. 541 677 .. 0.69 Alignments for each domain: == domain 1 score: 2.7 bits; conditional E-value: 0.17 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 +++la + + gd+++A+k+ e+ ++ ++ +gh FUN_002335-T1 12 SYQNLAYAFQSLGDFRKAIKYHEKHLKIAIEAGHR 46 68899999****************99999999987 PP == domain 2 score: 3.1 bits; conditional E-value: 0.12 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ l++ y + gd+++A++++e+ ++ ++ gh FUN_002335-T1 52 AYGSLGNAYQSLGDFRKAIDYCEKYLKIAIEVGHR 86 677899******************99999988886 PP == domain 3 score: 2.5 bits; conditional E-value: 0.19 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002335-T1 92 AYGNLGNAYQSLGDFRKAIEYHEKHLE 118 7889*****************999776 PP == domain 4 score: 2.2 bits; conditional E-value: 0.24 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002335-T1 132 AYGNLGNAYQSLGDFRKAIEYHEKHLE 158 57899****************999876 PP == domain 5 score: 2.5 bits; conditional E-value: 0.2 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002335-T1 172 AYGNLGNAYQSLGDFRKAIEYHEKHLE 198 7889*****************999776 PP == domain 6 score: 0.9 bits; conditional E-value: 0.59 RPN7 39 ledlaehyakigdlenAlkayerare 64 + l++ y + gd+++A+++ e+ +e FUN_002335-T1 239 YGSLGNAYQSLGDFRKAIEYHEKHLE 264 6679999*************999776 PP == domain 7 score: 1.0 bits; conditional E-value: 0.57 RPN7 39 ledlaehyakigdlenAlkayerare 64 + l++ y + gd+++A+++ e+ +e FUN_002335-T1 279 YGSLGNAYQSLGDFRKAIEYHEKHLE 304 6679999*************999776 PP == domain 8 score: 1.0 bits; conditional E-value: 0.55 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002335-T1 318 AYGSLGNAYRSLGDFRKAIEYHEKHLE 344 678899***************999776 PP == domain 9 score: 0.2 bits; conditional E-value: 0.99 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +++ y + gd+++A+++ e+ +e FUN_002335-T1 358 AYGSRGNAYQSLGDFRKAIEYHEKHLE 384 56778999*************999776 PP == domain 10 score: 1.3 bits; conditional E-value: 0.46 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002335-T1 398 AYGSLGNAYRSLGDFRKAIEYHEKHLE 424 788899***************999776 PP == domain 11 score: 1.4 bits; conditional E-value: 0.44 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002335-T1 438 AYGSLGNAYRSLGDFRKAIEYHEKHLE 464 678899***************999876 PP == domain 12 score: 0.9 bits; conditional E-value: 0.61 RPN7 39 ledlaehyakigdlenAlkayerare 64 + l++ y + gd+++A+++ e+ +e FUN_002335-T1 479 YGSLGNAYQSLGDFRKAIEYHEKHLE 504 6679999*************999776 PP == domain 13 score: 1.1 bits; conditional E-value: 0.52 RPN7 39 ledlaehyakigdlenAlkayerare 64 + l++ y + gd+++A+++ e+ +e FUN_002335-T1 519 YGSLGNAYQSLGDFRKAIEYHEKHLE 544 6679999*************999876 PP == domain 14 score: 5.2 bits; conditional E-value: 0.028 RPN7 39 ledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliekggd...werrnrlkvyeGlaalairkfke 131 + l++ y + gd+++A+++ e+ ++ ++ g + + +gi+++ + v+k +e ++ +e +++ ++ + G +++ ++f+ FUN_002335-T1 559 YGSLGNAYQSLGDFRKAIEYHEKYLKIAIEVGDRVGEGNAYGSLGIAYSLLGDVQKAIELYEKHLEIAKEvgdRKGEGIAYHNMGGEYFSLGQFEN 654 567888888889999999988888888888888888888888888888777777777776666666544321133333344444556677777777 PP RPN7 132 Aakllldslstft 144 A ++++ ++ f FUN_002335-T1 655 ALDKFVYAVEAFN 667 7777777766665 PP >> CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 114 125 .. 112 126 .. 0.90 2 ? 1.6 0.0 0.66 4.9e+02 11 22 .. 154 165 .. 152 166 .. 0.90 3 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 194 205 .. 192 206 .. 0.90 4 ? -2.1 0.0 9.2 6.9e+03 14 22 .. 223 231 .. 221 232 .. 0.88 5 ? -1.8 0.0 7.6 5.7e+03 11 22 .. 260 271 .. 259 272 .. 0.87 6 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 300 311 .. 298 312 .. 0.90 7 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 340 351 .. 338 352 .. 0.90 8 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 380 391 .. 378 392 .. 0.90 9 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 420 431 .. 418 432 .. 0.90 10 ? 1.6 0.0 0.66 4.9e+02 11 22 .. 460 471 .. 458 472 .. 0.90 11 ? 1.9 0.0 0.54 4.1e+02 11 22 .. 500 511 .. 498 512 .. 0.90 12 ? 1.6 0.0 0.66 4.9e+02 11 22 .. 540 551 .. 538 552 .. 0.90 13 ? 0.4 0.0 1.6 1.2e+03 11 22 .. 620 631 .. 619 632 .. 0.88 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 114 EKHLEIAKEVCD 125 89********99 PP == domain 2 score: 1.6 bits; conditional E-value: 0.66 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 154 EKHLEIAKEVSD 165 89*******998 PP == domain 3 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 194 EKHLEIAKEVCD 205 89********99 PP == domain 4 score: -2.1 bits; conditional E-value: 9.2 CaM_bdg_C0 14 lElARhaaD 22 lE+A+ + D FUN_002335-T1 223 LEIAKEVCD 231 8*****999 PP == domain 5 score: -1.8 bits; conditional E-value: 7.6 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A + D FUN_002335-T1 260 EKHLEIANEVSD 271 899****99988 PP == domain 6 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 300 EKHLEIAKEVCD 311 89********99 PP == domain 7 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 340 EKHLEIAKEVCD 351 89********99 PP == domain 8 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 380 EKHLEIAKEVCD 391 89********99 PP == domain 9 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 420 EKHLEIAKEVCD 431 89********99 PP == domain 10 score: 1.6 bits; conditional E-value: 0.66 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 460 EKHLEIAKEVSD 471 89*******998 PP == domain 11 score: 1.9 bits; conditional E-value: 0.54 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 500 EKHLEIAKEVCD 511 89********99 PP == domain 12 score: 1.6 bits; conditional E-value: 0.66 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 540 EKHLEIAKEVSD 551 89*******998 PP == domain 13 score: 0.4 bits; conditional E-value: 1.6 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002335-T1 620 EKHLEIAKEVGD 631 799*****9988 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.3 0.5 0.12 91 107 172 .. 113 173 .. 95 206 .. 0.84 2 ? -0.4 0.1 1.7 1.3e+03 107 139 .. 193 227 .. 179 258 .. 0.73 3 ? 2.5 0.0 0.21 1.6e+02 110 167 .. 222 274 .. 215 285 .. 0.84 4 ? 3.2 0.2 0.13 1e+02 106 165 .. 298 352 .. 284 359 .. 0.82 5 ? 2.8 0.2 0.17 1.3e+02 106 163 .. 338 390 .. 333 402 .. 0.74 6 ? 2.9 0.1 0.16 1.2e+02 107 162 .. 379 429 .. 374 434 .. 0.79 7 ? 4.9 0.1 0.04 30 107 167 .. 419 474 .. 414 486 .. 0.87 8 ? 3.8 0.2 0.085 64 107 168 .. 499 555 .. 493 593 .. 0.83 Alignments for each domain: == domain 1 score: 3.3 bits; conditional E-value: 0.12 ARM_TT21_C 107 qsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavGykLAf 172 ++++l++A+e++++v + + Ay lG +++ +++A+e+ ek +++ke s +vG A+ FUN_002335-T1 113 HEKHLEIAKEVCDRVGE-----GGAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGSAY 173 66778888999988866.....579999********************999999999999865555 PP == domain 2 score: -0.4 bits; conditional E-value: 1.7 ARM_TT21_C 107 qsgkldlAeeLlkkvlkynk..scakAyellGlia 139 ++++l++A+e++++v + n s + Ay+ l + + FUN_002335-T1 193 HEKHLEIAKEVCDRVGEGNAygSLGNAYQSLEIAK 227 56778888888888888774336667776655444 PP == domain 3 score: 2.5 bits; conditional E-value: 0.21 ARM_TT21_C 110 kldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavG 167 l++A+e++++v + + Ay lG +++ +++A+e+ ek ++++e s +vG FUN_002335-T1 222 SLEIAKEVCDRVGE-----GGAYGSLGNAYQSLGDFRKAIEYHEKHLEIANEVSDRVG 274 56778888888765.....569999********************9999999999988 PP == domain 4 score: 3.2 bits; conditional E-value: 0.13 ARM_TT21_C 106 iqsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspa 165 ++++l++A+e++++v + n Ay lG + + +++A+e+ ek +++ke + FUN_002335-T1 298 YHEKHLEIAKEVCDRVGEGN-----AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVCDR 352 56788999*******99877.....88888888888899999999888887777766555 PP == domain 5 score: 2.8 bits; conditional E-value: 0.17 ARM_TT21_C 106 iqsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskess 163 ++++l++A+e++++v + n Ay G +++ +++A+e+ ek +++ke FUN_002335-T1 338 YHEKHLEIAKEVCDRVGEGN-----AYGSRGNAYQSLGDFRKAIEYHEKHLEIAKEVC 390 56788999********9987.....666677777777777777777777766666655 PP == domain 6 score: 2.9 bits; conditional E-value: 0.16 ARM_TT21_C 107 qsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskes 162 ++++l++A+e++++v + n Ay lG + + +++A+e+ ek +++ke FUN_002335-T1 379 HEKHLEIAKEVCDRVGEGN-----AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEV 429 678899*********9877.....88888888888889999988888877777665 PP == domain 7 score: 4.9 bits; conditional E-value: 0.04 ARM_TT21_C 107 qsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavG 167 ++++l++A+e++++v + n Ay lG + + +++A+e+ ek +++ke s +vG FUN_002335-T1 419 HEKHLEIAKEVCDRVGEGN-----AYGSLGNAYRSLGDFRKAIEYHEKHLEIAKEVSDRVG 474 678899*********9877.....9999999999999**********99999999998888 PP == domain 8 score: 3.8 bits; conditional E-value: 0.085 ARM_TT21_C 107 qsgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavGy 168 ++++l++A+e++++v + + Ay lG +++ +++A+e+ ek +++ke s +vG FUN_002335-T1 499 HEKHLEIAKEVCDRVGE-----GGAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGE 555 67788999999999976.....6799999*******************99999999999985 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 9.4 7.1e+03 33 42 .] 15 24 .. 12 31 .. 0.61 2 ? 2.4 0.3 0.24 1.8e+02 3 21 .. 52 70 .. 50 79 .. 0.50 3 ? 3.9 0.2 0.083 62 30 42 .] 92 104 .. 91 111 .. 0.79 4 ? 3.1 0.2 0.15 1.1e+02 31 42 .] 133 144 .. 131 151 .. 0.69 5 ? 3.6 0.1 0.1 77 30 42 .] 172 184 .. 171 191 .. 0.75 6 ? -1.4 0.2 3.6 2.7e+03 29 40 .. 211 222 .. 211 223 .. 0.82 7 ? 1.9 0.2 0.35 2.6e+02 1 15 [. 243 257 .. 238 260 .. 0.77 8 ? 1.9 0.2 0.35 2.6e+02 1 15 [. 283 297 .. 278 300 .. 0.77 9 ? 5.9 0.1 0.019 14 1 15 [. 323 337 .. 323 341 .. 0.96 10 ? 2.0 0.3 0.32 2.4e+02 1 15 [. 363 377 .. 356 381 .. 0.71 11 ? 5.9 0.1 0.019 14 1 15 [. 403 417 .. 403 421 .. 0.96 12 ? 5.9 0.1 0.019 14 1 15 [. 443 457 .. 443 461 .. 0.96 13 ? 1.9 0.2 0.35 2.6e+02 1 15 [. 483 497 .. 478 500 .. 0.77 14 ? 1.9 0.2 0.35 2.6e+02 1 15 [. 523 537 .. 518 540 .. 0.77 15 ? 1.9 0.2 0.33 2.5e+02 1 15 [. 563 577 .. 558 581 .. 0.78 16 ? 2.1 0.1 0.3 2.3e+02 3 21 .. 605 623 .. 603 627 .. 0.81 17 ? 5.1 0.1 0.034 26 3 17 .. 645 659 .. 643 664 .. 0.82 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 9.4 TPR_11 33 nLGlayykqG 42 nL++a++ +G FUN_002335-T1 15 NLAYAFQSLG 24 6666666555 PP == domain 2 score: 2.4 bits; conditional E-value: 0.24 TPR_11 3 ayyeqGkyeeAieaYkkAl 21 ay ++G+ +++ +++kA+ FUN_002335-T1 52 AYGSLGNAYQSLGDFRKAI 70 4444444444444444444 PP == domain 3 score: 3.9 bits; conditional E-value: 0.083 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002335-T1 92 AYGNLGNAYQSLG 104 7888888888877 PP == domain 4 score: 3.1 bits; conditional E-value: 0.15 TPR_11 31 yynLGlayykqG 42 y nLG+ay+ +G FUN_002335-T1 133 YGNLGNAYQSLG 144 667777777766 PP == domain 5 score: 3.6 bits; conditional E-value: 0.1 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002335-T1 172 AYGNLGNAYQSLG 184 6778888888776 PP == domain 6 score: -1.4 bits; conditional E-value: 3.6 TPR_11 29 eayynLGlayyk 40 +ay LG+ay+ FUN_002335-T1 211 NAYGSLGNAYQS 222 58889*****85 PP == domain 7 score: 1.9 bits; conditional E-value: 0.35 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002335-T1 243 GNAYQSLGDFRKAIE 257 777777777777775 PP == domain 8 score: 1.9 bits; conditional E-value: 0.35 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002335-T1 283 GNAYQSLGDFRKAIE 297 777777777777775 PP == domain 9 score: 5.9 bits; conditional E-value: 0.019 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002335-T1 323 GNAYRSLGDFRKAIE 337 9*************7 PP == domain 10 score: 2.0 bits; conditional E-value: 0.32 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002335-T1 363 GNAYQSLGDFRKAIE 377 677777777777765 PP == domain 11 score: 5.9 bits; conditional E-value: 0.019 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002335-T1 403 GNAYRSLGDFRKAIE 417 9*************7 PP == domain 12 score: 5.9 bits; conditional E-value: 0.019 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002335-T1 443 GNAYRSLGDFRKAIE 457 9*************7 PP == domain 13 score: 1.9 bits; conditional E-value: 0.35 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002335-T1 483 GNAYQSLGDFRKAIE 497 777777777777775 PP == domain 14 score: 1.9 bits; conditional E-value: 0.35 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002335-T1 523 GNAYQSLGDFRKAIE 537 777777777777775 PP == domain 15 score: 1.9 bits; conditional E-value: 0.33 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002335-T1 563 GNAYQSLGDFRKAIE 577 777777777777776 PP == domain 16 score: 2.1 bits; conditional E-value: 0.3 TPR_11 3 ayyeqGkyeeAieaYkkAl 21 ay +G+ +Aie Y+k l FUN_002335-T1 605 AYSLLGDVQKAIELYEKHL 623 566789*********9855 PP == domain 17 score: 5.1 bits; conditional E-value: 0.034 TPR_11 3 ayyeqGkyeeAieaY 17 +y+++G++e+A+ ++ FUN_002335-T1 645 EYFSLGQFENALDKF 659 8**********9876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 454 (0.0177726); expected 510.9 (0.02) Passed bias filter: 416 (0.016285); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 37 (0.00144842); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 34 [number of targets reported over threshold] # CPU time: 0.62u 0.36s 00:00:00.98 Elapsed: 00:00:00.47 # Mc/sec: 9647.68 // Query: FUN_002336-T1 [L=163] Description: FUN_002336 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-09 38.3 0.0 2.2e-09 37.7 0.0 1.2 1 Proteasome Proteasome subunit 6.9e-08 32.2 1.2 1.1e-07 31.6 1.2 1.3 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.7 0.0 1.7e-13 2.2e-09 138 189 .] 57 108 .. 50 108 .. 0.96 Alignments for each domain: == domain 1 score: 37.7 bits; conditional E-value: 1.7e-13 Proteasome 138 iGsgsqaaygvlekeykedltleeavelakkalkealerdklsgknievavi 189 iG+gs aa++v+e+++k+d++l+ea +l+++a+ + + +d sg+++++++i FUN_002336-T1 57 IGYGSLAAMSVFESRCKPDMELDEAQKLVRDAIAAGIFNDLGSGSGVDLCII 108 9*************************************************97 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.6 1.2 8.5e-12 1.1e-07 1 35 [. 122 157 .. 122 157 .. 0.98 Alignments for each domain: == domain 1 score: 31.6 bits; conditional E-value: 8.5e-12 Pr_beta_C 1 PNergeRqgsYkfkrGTTAVLkekV.plklevveev 35 +N +g Rqg+Y + r TTAV ++++ p+ ++v+e++ FUN_002336-T1 122 ANDKGVRQGRYSYIRKTTAVVTKDIkPIVVDVTETT 157 8*********************************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (163 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 559 (0.021883); expected 510.9 (0.02) Passed bias filter: 525 (0.020552); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1632.45 // Query: FUN_002337-T1 [L=1365] Description: FUN_002337 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-184 581.3 35.8 2.7e-08 33.7 0.0 22.1 22 TPR_7 Tetratricopeptide repeat 1.9e-172 560.3 57.2 1.1e-17 64.4 0.2 12.4 13 TPR_12 Tetratricopeptide repeat 1e-148 478.2 121.7 9.8e-08 32.0 0.4 22.6 22 TPR_1 Tetratricopeptide repeat 2.7e-98 320.0 41.4 2.7e-05 24.5 0.0 21.7 22 TPR_10 Tetratricopeptide repeat 1.8e-93 299.3 98.0 0.0001 22.7 0.3 22.3 22 TPR_8 Tetratricopeptide repeat 3.7e-63 205.0 105.8 0.0036 17.8 0.2 23.0 23 TPR_2 Tetratricopeptide repeat 8.9e-52 176.8 0.0 1.3e-51 176.2 0.0 1.2 1 CHAT CHAT domain 4.3e-37 123.2 38.0 3.2 9.2 0.1 22.2 22 TPR_14 Tetratricopeptide repeat 6.4e-32 107.6 52.8 2.2 9.2 0.1 20.9 20 TPR_17 Tetratricopeptide repeat 1.1e-27 96.4 51.9 0.39 11.3 0.0 20.4 21 Rapsyn_N Rapsyn N-terminal myristoylation and linker 1e-24 88.0 3.6 0.00013 21.8 0.0 7.1 7 TPR_MalT MalT-like TPR region 6.7e-20 71.7 38.3 0.28 12.2 0.3 15.7 14 TPR_16 Tetratricopeptide repeat 1.4e-18 66.7 31.0 6.5 8.1 0.0 19.7 19 TPR_6 Tetratricopeptide repeat 1.4e-15 58.0 45.0 3.2 7.9 0.4 19.2 21 RPN7 26S proteasome subunit RPN7 1.7e-15 57.8 19.6 0.00057 19.9 0.1 6.4 7 SNAP Soluble NSF attachment protein, SNAP 1.8e-15 57.3 0.3 1.3e+02 3.3 0.0 17.6 21 DUF2977 Protein of unknown function (DUF2977) 1.6e-14 54.2 1.4 10 6.8 0.0 11.8 15 WH_Halo_primase Halobacteria primase winged helix domain 5.1e-14 52.2 0.0 1.9e+02 2.3 0.0 16.4 19 DBD_Tnp_Mut MuDR family transposase 5.7e-12 45.7 26.8 50 4.2 0.0 18.6 21 DUF7542 Family of unknown function (DUF7542) 1.5e-11 44.2 2.3 1.2e+02 4.3 0.0 15.4 16 TPR_4 Tetratricopeptide repeat 1.7e-10 41.3 18.4 35 4.2 0.0 16.6 19 TPR_15 Tetratricopeptide repeat 2.9e-10 40.1 48.0 15 6.6 0.0 19.9 21 PPR PPR repeat 7.7e-10 39.0 10.4 3.9 7.3 0.1 10.0 11 TPR_NPHP3 Nephrocystin-3 TPR domain 2.8e-08 34.1 31.2 30 5.2 0.0 16.7 20 TPR_9 Tetratricopeptide repeat 3e-08 33.2 14.7 0.21 10.6 0.3 8.5 8 TPR_IF140-IFT172 IF140/IFT172 TPR domain 2.3e-07 31.2 0.2 5.2e+02 1.3 0.0 12.1 19 CODH_A_N Carbon monoxide dehydrogenase subunit alpha 2.5e-07 31.4 28.6 17 6.3 0.2 13.0 17 TPR_19 Tetratricopeptide repeat 4.8e-06 26.5 2.2 9.8 5.7 0.0 8.1 12 Sec1 Sec1 family 6.5e-05 22.2 0.0 25 3.9 0.0 6.4 8 Transferase Transferase family 9e-05 23.2 23.1 1.3e+02 3.4 0.0 14.0 16 GGDEF_2 GGDEF-like domain 0.0022 18.2 0.0 95 3.1 0.0 7.2 11 TPR_COPA_B COPA/B TPR domain ------ inclusion threshold ------ 0.025 15.3 51.8 76 4.0 0.0 17.7 19 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth A 0.15 12.9 5.0 3.4e+02 2.0 0.0 6.6 8 DHR-2_Lobe_A DHR-2, Lobe A 2.7 8.7 15.1 3e+02 2.1 0.0 8.8 9 FbpC_C_terminal FbpC C-terminal regulatory nucleotide bindi Domain annotation for each model (and alignments): >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 2.7e-05 0.02 8 36 .] 41 69 .. 39 69 .. 0.94 2 ! 22.0 0.0 2.1e-07 0.00016 3 35 .. 76 108 .. 75 109 .. 0.91 3 ! 26.2 0.0 9.2e-09 6.9e-06 1 35 [. 114 148 .. 114 149 .. 0.93 4 ! 29.3 0.0 9.7e-10 7.3e-07 1 35 [. 154 188 .. 154 189 .. 0.92 5 ! 27.9 0.0 2.6e-09 2e-06 3 35 .. 196 228 .. 194 229 .. 0.93 6 ! 31.6 0.1 1.7e-10 1.3e-07 1 35 [. 234 268 .. 234 269 .. 0.96 7 ! 26.2 0.0 9.4e-09 7.1e-06 1 35 [. 274 308 .. 274 309 .. 0.93 8 ! 26.0 0.0 1.1e-08 8.3e-06 1 35 [. 314 348 .. 314 349 .. 0.94 9 ! 26.6 0.1 6.8e-09 5.1e-06 1 34 [. 354 387 .. 354 389 .. 0.92 10 ! 29.5 0.0 8.5e-10 6.4e-07 1 35 [. 394 428 .. 394 429 .. 0.95 11 ! 32.5 0.0 9.3e-11 7e-08 1 35 [. 434 468 .. 434 469 .. 0.96 12 ! 33.7 0.0 3.6e-11 2.7e-08 1 35 [. 474 508 .. 474 509 .. 0.96 13 ! 32.3 0.0 1e-10 7.8e-08 1 35 [. 514 548 .. 514 549 .. 0.95 14 ! 29.5 0.0 8.2e-10 6.2e-07 1 35 [. 554 588 .. 554 589 .. 0.96 15 ! 27.5 0.0 3.5e-09 2.6e-06 1 35 [. 594 628 .. 594 629 .. 0.95 16 ! 27.0 0.0 5.3e-09 4e-06 1 35 [. 634 668 .. 634 669 .. 0.93 17 ! 26.6 0.0 6.8e-09 5.1e-06 1 35 [. 674 708 .. 674 709 .. 0.93 18 ! 31.0 0.0 2.7e-10 2e-07 1 35 [. 714 748 .. 714 749 .. 0.95 19 ! 27.7 0.0 3e-09 2.3e-06 1 35 [. 754 788 .. 754 789 .. 0.95 20 ! 28.4 0.1 1.9e-09 1.4e-06 1 35 [. 794 828 .. 794 829 .. 0.93 21 ! 27.4 0.0 3.8e-09 2.9e-06 1 35 [. 834 868 .. 834 869 .. 0.93 22 ? -0.4 0.0 3.1 2.4e+03 1 18 [. 874 891 .. 874 899 .. 0.85 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 2.7e-05 TPR_7 8 iyrklGdydeAirlyerlLalakdpedre 36 +++++G +++Ai+++e++L ++++ +dr+ FUN_002337-T1 41 AFHSQGYFRKAIEYHEKHLKITMEVGDRA 69 699***********************995 PP == domain 2 score: 22.0 bits; conditional E-value: 2.1e-07 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La+++++lGd+++Ai+++e++L +a + ++r FUN_002337-T1 76 QNLAHAFQSLGDFRKAIKYHEKHLKIAIEAGHR 108 69**********************999877776 PP == domain 3 score: 26.2 bits; conditional E-value: 9.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L +a + ++r FUN_002337-T1 114 AYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEVGHR 148 789************************99888876 PP == domain 4 score: 29.3 bits; conditional E-value: 9.7e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGNR 188 678*************************9888876 PP == domain 5 score: 27.9 bits; conditional E-value: 2.6e-09 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 ++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002337-T1 196 GSLGNAYRSLGDFRKAIEYHEKHLEIAVEVGHR 228 68*************************999887 PP == domain 6 score: 31.6 bits; conditional E-value: 1.7e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002337-T1 234 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEASDR 268 789***************************99997 PP == domain 7 score: 26.2 bits; conditional E-value: 9.4e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L++a + ++r FUN_002337-T1 274 AYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGNR 308 789*************************9888876 PP == domain 8 score: 26.0 bits; conditional E-value: 1.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y +lGd+++Ai+++e++L++a + ++r FUN_002337-T1 314 AYGNLGIAYDSLGDFRKAIEYHEKHLEIAIEVGHR 348 789*************************9988876 PP == domain 9 score: 26.6 bits; conditional E-value: 6.8e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L+++y++lGd+++Ai+++e++L++a + +d FUN_002337-T1 354 AYASLGNAYQSLGDFRKAIEYHEKHLEIAIEVSD 387 7899************************987776 PP == domain 10 score: 29.5 bits; conditional E-value: 8.5e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L++ak+ ++r FUN_002337-T1 394 AYGNLGIAYHSLGDFRKAIEYHEKHLEIAKEVSHR 428 789***************************99887 PP == domain 11 score: 32.5 bits; conditional E-value: 9.3e-11 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002337-T1 434 AYGNLGNAYESLGDFRKAIEYHEKHLEIAKKVSDR 468 789****************************9998 PP == domain 12 score: 33.7 bits; conditional E-value: 3.6e-11 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002337-T1 474 AYGNLGNAYESLGDFQKAIEYHEKHLEIAKEVSDR 508 789****************************9998 PP == domain 13 score: 32.3 bits; conditional E-value: 1e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ ++r FUN_002337-T1 514 AYGNLGNAYESLGDFQNAIEYHEKHLEIAKEVSHR 548 789***************************99887 PP == domain 14 score: 29.5 bits; conditional E-value: 8.2e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L++ak+ +dr FUN_002337-T1 554 AYGNLGNTYQSLGDFRKAIEYHEKDLEIAKEVSDR 588 789****************************9998 PP == domain 15 score: 27.5 bits; conditional E-value: 3.5e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e+ L++ak+ ++r FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEKDLEIAKEVGNR 628 789***************************99987 PP == domain 16 score: 27.0 bits; conditional E-value: 5.3e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002337-T1 634 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNR 668 7899************************9888876 PP == domain 17 score: 26.6 bits; conditional E-value: 6.8e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002337-T1 674 AYGSLGNAYQSLGDFRKAIGYHEKHLEIAIEVGHR 708 7899************************9988876 PP == domain 18 score: 31.0 bits; conditional E-value: 2.7e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002337-T1 714 AYGSLGNAYESLGDFRKAIEYHEKHLEIAKEVSDR 748 7899***************************9998 PP == domain 19 score: 27.7 bits; conditional E-value: 3e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lG++++Ai+++e++L++a d ++r FUN_002337-T1 754 AYGNLGNAYQSLGEFRKAIKCHEKHLEIAIDVGHR 788 789****************************9987 PP == domain 20 score: 28.4 bits; conditional E-value: 1.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd +eAi++ye++L++a + ++r FUN_002337-T1 794 AYGSLGNAYQSLGDVREAIEYYEKHLEIAIEVGHR 828 7899************************9988876 PP == domain 21 score: 27.4 bits; conditional E-value: 3.8e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002337-T1 834 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNR 868 7899*************************998887 PP == domain 22 score: -0.4 bits; conditional E-value: 3.1 TPR_7 1 aLsaLariyrklGdydeA 18 +++++++ y +lG++++A FUN_002337-T1 874 SHHNIGHGYFSLGQFENA 891 589*************99 PP >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 0.5 7e-10 5.2e-07 3 75 .. 32 102 .. 30 104 .. 0.88 2 ! 51.2 0.6 2e-16 1.5e-13 8 75 .. 77 142 .. 70 144 .. 0.96 3 ! 59.4 0.6 5.5e-19 4.1e-16 4 75 .. 113 182 .. 110 184 .. 0.96 4 ! 59.1 0.7 6.9e-19 5.2e-16 4 75 .. 153 222 .. 150 224 .. 0.97 5 ! 57.9 0.5 1.7e-18 1.3e-15 6 77 .] 195 264 .. 190 264 .. 0.95 6 ! 62.1 0.4 7.9e-20 5.9e-17 4 75 .. 273 342 .. 270 344 .. 0.96 7 ! 59.6 0.7 4.7e-19 3.5e-16 4 77 .] 353 424 .. 351 424 .. 0.95 8 ! 64.4 0.2 1.5e-20 1.1e-17 4 77 .] 433 504 .. 430 504 .. 0.97 9 ! 59.2 0.2 6.2e-19 4.7e-16 4 77 .] 513 584 .. 510 584 .. 0.97 10 ! 56.3 0.2 5.2e-18 3.9e-15 5 75 .. 594 662 .. 591 664 .. 0.97 11 ! 54.0 0.4 2.6e-17 2e-14 4 77 .] 673 744 .. 670 744 .. 0.96 12 ! 56.2 0.3 5.6e-18 4.2e-15 4 75 .. 753 822 .. 750 824 .. 0.96 13 ! 36.5 0.0 7.9e-12 5.9e-09 4 64 .. 833 891 .. 830 903 .. 0.91 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 7e-10 TPR_12 3 atalnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+a+ + + +g + +A+e++ek l + ++ +d+ ++ ++nL+ +++ lgd+++A++++e+ l+ia FUN_002337-T1 32 ANAYGYTSIAFHSQGYFRKAIEYHEKHLKITMEV--GDRAGEEKGYQNLAHAFQSLGDFRKAIKYHEKHLKIA 102 556644445556799999****************..99*********************************98 PP == domain 2 score: 51.2 bits; conditional E-value: 2e-16 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 nlA++ + lg++ +A++++ek l +a ++ +++ ++ +a+ nLg +y lgd+++A+e++e+ l+ia FUN_002337-T1 77 NLAHAFQSLGDFRKAIKYHEKHLKIAIEA--GHRVGEGNAYGNLGNAYKSLGDFRKAIEYHEKHLKIA 142 9*************************999..99*********************************98 PP == domain 3 score: 59.4 bits; conditional E-value: 5.5e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++ lg++ +A+e++ek l +a ++ +++ ++ a+rnLg +y+ lgd+++A+e++e+ leia FUN_002337-T1 113 NAYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEV--GHRVGEGSAYRNLGNAYRSLGDFRKAIEYHEKHLEIA 182 799******************************..99*********************************98 PP == domain 4 score: 59.1 bits; conditional E-value: 6.9e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a++nl++++r lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y+ lgd+++A+e++e+ leia FUN_002337-T1 153 SAYRNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGRARGSLGNAYRSLGDFRKAIEYHEKHLEIA 222 7999*****************************..99*********************************96 PP == domain 5 score: 57.9 bits; conditional E-value: 1.7e-18 TPR_12 6 lnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 l++++r lg++ +A+e++ek le+a ++ +++ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002337-T1 195 RGSLGNAYRSLGDFRKAIEYHEKHLEIAVEV--GHRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 264 5569************************999..99**********************************986 PP == domain 6 score: 62.1 bits; conditional E-value: 7.9e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ k le+a ++ +++ ++ +a+ nLg++y lgd+++A+e++e+ leia FUN_002337-T1 273 NAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEV--GNRVGEGNAYGNLGIAYDSLGDFRKAIEYHEKHLEIA 342 799******************************..99*********************************98 PP == domain 7 score: 59.6 bits; conditional E-value: 4.7e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+++++ lg++ +A+e++ek le+a ++ d ++ a+ nLg++y+ lgd+++A+e++e+ leia++ FUN_002337-T1 353 NAYASLGNAYQSLGDFRKAIEYHEKHLEIAIEV--SDQVGEGSAYGNLGIAYHSLGDFRKAIEYHEKHLEIAKE 424 56767****************************..9***********************************986 PP == domain 8 score: 64.4 bits; conditional E-value: 1.5e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl++++ lg++ +A+e++ek le+a+++ d+ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002337-T1 433 SAYGNLGNAYESLGDFRKAIEYHEKHLEIAKKV--SDRVGEGSAYGNLGNAYESLGDFQKAIEYHEKHLEIAKE 504 7999*****************************..9***********************************986 PP == domain 9 score: 59.2 bits; conditional E-value: 6.2e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl++++ lg++++A+e++ek le+a+++ ++ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002337-T1 513 NAYGNLGNAYESLGDFQNAIEYHEKHLEIAKEV--SHRVGEGSAYGNLGNTYQSLGDFRKAIEYHEKDLEIAKE 584 799******************************..9*******************************9999985 PP == domain 10 score: 56.3 bits; conditional E-value: 5.2e-18 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 a+ nl+ +++ lg++ +A+e++ek le+a+++ +++ ++ +a+ Lg +y+ lgd+++A+e++e+ leia FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEKDLEIAKEV--GNRVGEGNAYGSLGNAYQSLGDFRKAIEYHEKHLEIA 662 799*****************************..99*********************************98 PP == domain 11 score: 54.0 bits; conditional E-value: 2.6e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+++++ lg++ +A+ ++ek le+a ++ +++ ++ +a+ Lg +y+ lgd+++A+e++e+ leia++ FUN_002337-T1 673 NAYGSLGNAYQSLGDFRKAIGYHEKHLEIAIEV--GHRVGEENAYGSLGNAYESLGDFRKAIEYHEKHLEIAKE 744 78989****************************..99**********************************986 PP == domain 12 score: 56.2 bits; conditional E-value: 5.6e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A++++ek le+a + +++ ++ +a+ Lg +y+ lgd +eA+e++e+ leia FUN_002337-T1 753 NAYGNLGNAYQSLGEFRKAIKCHEKHLEIAIDV--GHRVGEGNAYGSLGNAYQSLGDVREAIEYYEKHLEIA 822 799****************************99..99*********************************98 PP == domain 13 score: 36.5 bits; conditional E-value: 7.9e-12 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeA 64 +a+ l+++++ lg++ +A+e++ek le+a ++ +++ ++ ++++n+g y+ lg++e A FUN_002337-T1 833 NAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV--GNRAGEGISHHNIGHGYFSLGQFENA 891 78989****************************..99*********************998 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.1 0.17 1.2e+02 10 30 .. 41 61 .. 40 61 .. 0.83 2 ! 21.1 0.5 3.6e-07 0.00027 2 30 .. 73 101 .. 72 102 .. 0.94 3 ! 29.3 0.8 9.3e-10 7e-07 2 30 .. 113 141 .. 112 142 .. 0.95 4 ! 29.4 0.3 8.9e-10 6.7e-07 3 30 .. 154 181 .. 152 182 .. 0.95 5 ! 24.4 0.1 3.4e-08 2.5e-05 3 30 .. 194 221 .. 192 222 .. 0.92 6 ! 31.0 0.4 2.8e-10 2.1e-07 3 31 .. 234 262 .. 232 264 .. 0.94 7 ! 26.5 0.8 7.2e-09 5.4e-06 2 30 .. 273 301 .. 272 302 .. 0.94 8 ! 27.3 0.3 3.9e-09 2.9e-06 2 30 .. 313 341 .. 312 342 .. 0.95 9 ! 26.9 0.6 5.5e-09 4.1e-06 2 30 .. 353 381 .. 352 382 .. 0.95 10 ! 29.0 0.2 1.2e-09 8.8e-07 3 31 .. 394 422 .. 392 424 .. 0.94 11 ! 30.5 0.4 3.9e-10 3e-07 3 31 .. 434 462 .. 432 464 .. 0.94 12 ! 32.0 0.4 1.3e-10 9.8e-08 3 31 .. 474 502 .. 472 504 .. 0.94 13 ! 30.2 0.8 5e-10 3.7e-07 2 31 .. 513 542 .. 512 544 .. 0.94 14 ! 24.4 0.1 3.3e-08 2.5e-05 3 26 .. 554 577 .. 552 583 .. 0.93 15 ! 22.7 0.3 1.1e-07 8.5e-05 3 26 .. 594 617 .. 593 623 .. 0.93 16 ! 27.3 0.3 4.1e-09 3.1e-06 2 30 .. 633 661 .. 632 662 .. 0.95 17 ! 22.5 0.2 1.3e-07 0.0001 2 30 .. 673 701 .. 672 702 .. 0.95 18 ! 27.1 0.5 4.6e-09 3.4e-06 2 31 .. 713 742 .. 712 744 .. 0.94 19 ! 30.0 0.5 5.7e-10 4.3e-07 2 30 .. 753 781 .. 752 782 .. 0.95 20 ! 29.1 0.4 1.1e-09 7.9e-07 2 30 .. 793 821 .. 792 822 .. 0.95 21 ! 27.3 0.3 4.1e-09 3.1e-06 2 30 .. 833 861 .. 832 862 .. 0.95 22 ? 6.8 0.0 0.012 8.8 4 20 .. 875 891 .. 873 891 .. 0.92 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.17 TPR_1 10 ayfklgkydeAleyyekALel 30 a++++g + +A+ey ek L++ FUN_002337-T1 41 AFHSQGYFRKAIEYHEKHLKI 61 667778899*******99986 PP == domain 2 score: 21.1 bits; conditional E-value: 3.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k + nl++a+++lg++ +A++y ek L++ FUN_002337-T1 73 KGYQNLAHAFQSLGDFRKAIKYHEKHLKI 101 5799***********************98 PP == domain 3 score: 29.3 bits; conditional E-value: 9.3e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay +lg++ +A+ey ek L++ FUN_002337-T1 113 NAYGNLGNAYKSLGDFRKAIEYHEKHLKI 141 69*************************98 PP == domain 4 score: 29.4 bits; conditional E-value: 8.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEYHEKHLEI 181 99************************98 PP == domain 5 score: 24.4 bits; conditional E-value: 3.4e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a lGnay++lg++ +A+ey ek Le+ FUN_002337-T1 194 ARGSLGNAYRSLGDFRKAIEYHEKHLEI 221 6678**********************98 PP == domain 6 score: 31.0 bits; conditional E-value: 2.8e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002337-T1 234 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 262 9**************************96 PP == domain 7 score: 26.5 bits; conditional E-value: 7.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey k Le+ FUN_002337-T1 273 NAYGNLGNAYQSLGDFRKAIEYHAKHLEI 301 69********************9999998 PP == domain 8 score: 27.3 bits; conditional E-value: 3.9e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlG ay +lg++ +A+ey ek Le+ FUN_002337-T1 313 NAYGNLGIAYDSLGDFRKAIEYHEKHLEI 341 69*************************98 PP == domain 9 score: 26.9 bits; conditional E-value: 5.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002337-T1 353 NAYASLGNAYQSLGDFRKAIEYHEKHLEI 381 59*************************98 PP == domain 10 score: 29.0 bits; conditional E-value: 1.2e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlG ay++lg++ +A+ey ek Le+ FUN_002337-T1 394 AYGNLGIAYHSLGDFRKAIEYHEKHLEIA 422 9**************************96 PP == domain 11 score: 30.5 bits; conditional E-value: 3.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay +lg++ +A+ey ek Le+ FUN_002337-T1 434 AYGNLGNAYESLGDFRKAIEYHEKHLEIA 462 9**************************96 PP == domain 12 score: 32.0 bits; conditional E-value: 1.3e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay +lg++++A+ey ek Le+ FUN_002337-T1 474 AYGNLGNAYESLGDFQKAIEYHEKHLEIA 502 9**************************96 PP == domain 13 score: 30.2 bits; conditional E-value: 5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGnay +lg+++ A+ey ek Le+ FUN_002337-T1 513 NAYGNLGNAYESLGDFQNAIEYHEKHLEIA 542 69**************************96 PP == domain 14 score: 24.4 bits; conditional E-value: 3.3e-08 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ nlGn+y++lg++ +A+ey ek FUN_002337-T1 554 AYGNLGNTYQSLGDFRKAIEYHEK 577 9********************998 PP == domain 15 score: 22.7 bits; conditional E-value: 1.1e-07 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ nlG ay++lg++ +A+ey ek FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEK 617 8********************998 PP == domain 16 score: 27.3 bits; conditional E-value: 4.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002337-T1 633 NAYGSLGNAYQSLGDFRKAIEYHEKHLEI 661 59*************************98 PP == domain 17 score: 22.5 bits; conditional E-value: 1.3e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ y ek Le+ FUN_002337-T1 673 NAYGSLGNAYQSLGDFRKAIGYHEKHLEI 701 59*************************98 PP == domain 18 score: 27.1 bits; conditional E-value: 4.6e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002337-T1 713 NAYGSLGNAYESLGDFRKAIEYHEKHLEIA 742 59**************************96 PP == domain 19 score: 30.0 bits; conditional E-value: 5.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+++ ek Le+ FUN_002337-T1 753 NAYGNLGNAYQSLGEFRKAIKCHEKHLEI 781 69*************************98 PP == domain 20 score: 29.1 bits; conditional E-value: 1.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg+ eA+eyyek Le+ FUN_002337-T1 793 NAYGSLGNAYQSLGDVREAIEYYEKHLEI 821 59*************************98 PP == domain 21 score: 27.3 bits; conditional E-value: 4.1e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002337-T1 833 NAYGSLGNAYQSLGDFRKAIEYHEKHLEI 861 59*************************98 PP == domain 22 score: 6.8 bits; conditional E-value: 0.012 TPR_1 4 lynlGnayfklgkydeA 20 + n+G+ yf+lg+++ A FUN_002337-T1 875 HHNIGHGYFSLGQFENA 891 88*************98 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 3.1 2.3e+03 24 36 .. 47 59 .. 33 62 .. 0.74 2 ! 7.9 0.1 0.0061 4.6 5 32 .. 75 102 .. 75 105 .. 0.88 3 ! 15.6 0.0 2.2e-05 0.017 4 34 .. 114 144 .. 112 145 .. 0.90 4 ! 18.5 0.1 2.8e-06 0.0021 3 35 .. 153 185 .. 152 185 .. 0.92 5 ! 13.3 0.1 0.00012 0.091 4 34 .. 194 224 .. 193 225 .. 0.89 6 ! 20.5 0.1 6.5e-07 0.00049 3 35 .. 233 265 .. 232 268 .. 0.94 7 ! 15.8 0.1 2e-05 0.015 4 34 .. 274 304 .. 272 305 .. 0.90 8 ! 13.6 0.0 9.6e-05 0.072 4 35 .. 314 345 .. 312 345 .. 0.91 9 ! 15.2 0.0 2.9e-05 0.022 4 35 .. 354 385 .. 352 387 .. 0.92 10 ! 18.1 0.0 3.7e-06 0.0028 3 35 .. 393 425 .. 392 426 .. 0.96 11 ! 18.5 0.0 2.8e-06 0.0021 3 35 .. 433 465 .. 432 468 .. 0.95 12 ! 19.8 0.0 1.1e-06 0.00082 3 35 .. 473 505 .. 472 508 .. 0.95 13 ! 18.4 0.0 2.9e-06 0.0022 4 35 .. 514 545 .. 512 546 .. 0.95 14 ! 24.5 0.0 3.5e-08 2.7e-05 3 35 .. 553 585 .. 552 588 .. 0.95 15 ! 21.0 0.0 4.4e-07 0.00033 4 35 .. 594 625 .. 593 625 .. 0.96 16 ! 14.7 0.0 4.3e-05 0.032 4 34 .. 634 664 .. 632 665 .. 0.91 17 ! 12.4 0.0 0.00023 0.17 4 34 .. 674 704 .. 672 705 .. 0.91 18 ! 14.1 0.0 6.6e-05 0.05 4 35 .. 714 745 .. 713 748 .. 0.93 19 ! 14.1 0.0 6.9e-05 0.052 4 31 .. 754 781 .. 752 785 .. 0.90 20 ! 16.9 0.1 8.7e-06 0.0065 4 35 .. 794 825 .. 792 825 .. 0.91 21 ! 14.7 0.0 4.3e-05 0.032 4 34 .. 834 864 .. 832 865 .. 0.91 22 ? -1.1 0.0 4 3e+03 6 21 .. 876 891 .. 876 891 .. 0.91 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 3.1 TPR_10 24 lleealairervl 36 ++++a++ +e++l FUN_002337-T1 47 YFRKAIEYHEKHL 59 6677777777765 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0061 TPR_10 5 lnnLanalraqgryeeAeelleealair 32 + nLa a +++g++ A +++e+ l+i+ FUN_002337-T1 75 YQNLAHAFQSLGDFRKAIKYHEKHLKIA 102 67********************977776 PP == domain 3 score: 15.6 bits; conditional E-value: 2.2e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na+ ++g++ A e++e+ l+i+ + FUN_002337-T1 114 AYGNLGNAYKSLGDFRKAIEYHEKHLKIAIE 144 899********************98888766 PP == domain 4 score: 18.5 bits; conditional E-value: 2.8e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na+r++g++ A e++e+ l+i+ +v FUN_002337-T1 153 SAYRNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 185 799**********************99998765 PP == domain 5 score: 13.3 bits; conditional E-value: 0.00012 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+r++g++ A e++e+ l+i+ + FUN_002337-T1 194 ARGSLGNAYRSLGDFRKAIEYHEKHLEIAVE 224 6779********************9998876 PP == domain 6 score: 20.5 bits; conditional E-value: 6.5e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A e++e+ l+i++++ FUN_002337-T1 233 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEA 265 79***************************9986 PP == domain 7 score: 15.8 bits; conditional E-value: 2e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na++++g++ A e++ + l+i+ + FUN_002337-T1 274 AYGNLGNAYQSLGDFRKAIEYHAKHLEIAIE 304 899*******************998888766 PP == domain 8 score: 13.6 bits; conditional E-value: 9.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a+ ++g++ A e++e+ l+i+ +v FUN_002337-T1 314 AYGNLGIAYDSLGDFRKAIEYHEKHLEIAIEV 345 899*********************99998765 PP == domain 9 score: 15.2 bits; conditional E-value: 2.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+ +v FUN_002337-T1 354 AYASLGNAYQSLGDFRKAIEYHEKHLEIAIEV 385 7999********************99998876 PP == domain 10 score: 18.1 bits; conditional E-value: 3.7e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+ a+ ++g++ A e++e+ l+i+++v FUN_002337-T1 393 SAYGNLGIAYHSLGDFRKAIEYHEKHLEIAKEV 425 79***************************9997 PP == domain 11 score: 18.5 bits; conditional E-value: 2.8e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na+ ++g++ A e++e+ l+i+++v FUN_002337-T1 433 SAYGNLGNAYESLGDFRKAIEYHEKHLEIAKKV 465 79****************************998 PP == domain 12 score: 19.8 bits; conditional E-value: 1.1e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na+ ++g+++ A e++e+ l+i+++v FUN_002337-T1 473 SAYGNLGNAYESLGDFQKAIEYHEKHLEIAKEV 505 79****************************998 PP == domain 13 score: 18.4 bits; conditional E-value: 2.9e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+ ++g+++ A e++e+ l+i+++v FUN_002337-T1 514 AYGNLGNAYESLGDFQNAIEYHEKHLEIAKEV 545 899*************************9997 PP == domain 14 score: 24.5 bits; conditional E-value: 3.5e-08 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+n+++++g++ A e++e+ l+i+++v FUN_002337-T1 553 SAYGNLGNTYQSLGDFRKAIEYHEKDLEIAKEV 585 79*****************************98 PP == domain 15 score: 21.0 bits; conditional E-value: 4.4e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a++++g++ A e++e+ l+i+++v FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEKDLEIAKEV 625 799**************************997 PP == domain 16 score: 14.7 bits; conditional E-value: 4.3e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++e+ l+i+ + FUN_002337-T1 634 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIE 664 7999********************9999876 PP == domain 17 score: 12.4 bits; conditional E-value: 0.00023 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A ++e+ l+i+ + FUN_002337-T1 674 AYGSLGNAYQSLGDFRKAIGYHEKHLEIAIE 704 7999********************9999876 PP == domain 18 score: 14.1 bits; conditional E-value: 6.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+ ++g++ A e++e+ l+i+++v FUN_002337-T1 714 AYGSLGNAYESLGDFRKAIEYHEKHLEIAKEV 745 7999************************9998 PP == domain 19 score: 14.1 bits; conditional E-value: 6.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealai 31 ++ nL+na++++g++ A + +e+ l+i FUN_002337-T1 754 AYGNLGNAYQSLGEFRKAIKCHEKHLEI 781 899*******************997777 PP == domain 20 score: 16.9 bits; conditional E-value: 8.7e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g+ eA e++e+ l+i+ +v FUN_002337-T1 794 AYGSLGNAYQSLGDVREAIEYYEKHLEIAIEV 825 7999********************99998765 PP == domain 21 score: 14.7 bits; conditional E-value: 4.3e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na++++g++ A e++e+ l+i+ + FUN_002337-T1 834 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIE 864 7999********************9999876 PP == domain 22 score: -1.1 bits; conditional E-value: 4 TPR_10 6 nnLanalraqgryeeA 21 +n++ ++++g++e A FUN_002337-T1 876 HNIGHGYFSLGQFENA 891 79***********976 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 2.4 1.8e+03 12 26 .. 43 57 .. 40 62 .. 0.71 2 ! 13.8 0.2 9.5e-05 0.072 3 30 .. 74 101 .. 72 102 .. 0.88 3 ! 19.8 0.3 1.2e-06 0.00087 3 30 .. 114 141 .. 112 142 .. 0.89 4 ! 15.8 0.1 2.2e-05 0.016 3 30 .. 154 181 .. 152 182 .. 0.88 5 ! 14.5 0.0 5.5e-05 0.041 2 30 .. 193 221 .. 192 222 .. 0.87 6 ! 20.7 0.2 5.8e-07 0.00044 2 32 .. 233 263 .. 232 264 .. 0.92 7 ! 17.4 0.3 6.9e-06 0.0051 3 23 .. 274 294 .. 272 302 .. 0.89 8 ! 16.3 0.1 1.5e-05 0.011 3 30 .. 314 341 .. 312 342 .. 0.90 9 ! 16.9 0.3 9.7e-06 0.0073 3 30 .. 354 381 .. 352 382 .. 0.90 10 ! 18.1 0.1 3.8e-06 0.0029 2 32 .. 393 423 .. 392 424 .. 0.91 11 ! 21.4 0.1 3.5e-07 0.00027 2 32 .. 433 463 .. 432 465 .. 0.92 12 ! 22.2 0.3 2e-07 0.00015 2 32 .. 473 503 .. 472 504 .. 0.92 13 ! 21.9 0.3 2.3e-07 0.00017 3 32 .. 514 543 .. 512 544 .. 0.91 14 ! 19.1 0.1 1.9e-06 0.0014 2 30 .. 553 581 .. 552 584 .. 0.87 15 ! 15.8 0.2 2.1e-05 0.016 3 30 .. 594 621 .. 592 624 .. 0.88 16 ! 16.9 0.2 9.4e-06 0.0071 3 30 .. 634 661 .. 632 662 .. 0.90 17 ! 11.1 0.1 0.00069 0.52 3 26 .. 674 697 .. 672 702 .. 0.83 18 ! 18.1 0.3 4e-06 0.003 3 32 .. 714 743 .. 712 744 .. 0.91 19 ! 16.2 0.2 1.6e-05 0.012 3 30 .. 754 781 .. 752 782 .. 0.90 20 ! 22.7 0.3 1.3e-07 0.0001 3 30 .. 794 821 .. 792 822 .. 0.93 21 ! 16.9 0.2 9.4e-06 0.0071 3 30 .. 834 861 .. 832 862 .. 0.90 22 ? 3.9 0.0 0.14 1e+02 4 20 .. 875 891 .. 874 891 .. 0.93 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 2.4 TPR_8 12 lklgdyeeAkeyyek 26 +++g++ +A+ey ek FUN_002337-T1 43 HSQGYFRKAIEYHEK 57 677888888888666 PP == domain 2 score: 13.8 bits; conditional E-value: 9.5e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 y+nl+++ ++lgd+ +A++y ek l++ FUN_002337-T1 74 GYQNLAHAFQSLGDFRKAIKYHEKHLKI 101 69*******************8886665 PP == domain 3 score: 19.8 bits; conditional E-value: 1.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek l++ FUN_002337-T1 114 AYGNLGNAYKSLGDFRKAIEYHEKHLKI 141 9********************8886665 PP == domain 4 score: 15.8 bits; conditional E-value: 2.2e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEYHEKHLEI 181 6779*****************9987776 PP == domain 5 score: 14.5 bits; conditional E-value: 5.5e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +a lG++y++lgd+ +A+ey ek le+ FUN_002337-T1 193 RARGSLGNAYRSLGDFRKAIEYHEKHLEI 221 56778*****************9987776 PP == domain 6 score: 20.7 bits; conditional E-value: 5.8e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002337-T1 233 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 263 59********************999998875 PP == domain 7 score: 17.4 bits; conditional E-value: 6.9e-06 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay nlG++y++lgd+ +A+ey FUN_002337-T1 274 AYGNLGNAYQSLGDFRKAIEY 294 9*******************9 PP == domain 8 score: 16.3 bits; conditional E-value: 1.5e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG +y +lgd+ +A+ey ek le+ FUN_002337-T1 314 AYGNLGIAYDSLGDFRKAIEYHEKHLEI 341 8********************9987776 PP == domain 9 score: 16.9 bits; conditional E-value: 9.7e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002337-T1 354 AYASLGNAYQSLGDFRKAIEYHEKHLEI 381 89*******************9987776 PP == domain 10 score: 18.1 bits; conditional E-value: 3.8e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG +y++lgd+ +A+ey ek le+++ FUN_002337-T1 393 SAYGNLGIAYHSLGDFRKAIEYHEKHLEIAK 423 59********************999998875 PP == domain 11 score: 21.4 bits; conditional E-value: 3.5e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002337-T1 433 SAYGNLGNAYESLGDFRKAIEYHEKHLEIAK 463 59********************999999886 PP == domain 12 score: 22.2 bits; conditional E-value: 2e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+++A+ey ek le+++ FUN_002337-T1 473 SAYGNLGNAYESLGDFQKAIEYHEKHLEIAK 503 59********************999998875 PP == domain 13 score: 21.9 bits; conditional E-value: 2.3e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG++y++lgd+++A+ey ek le+++ FUN_002337-T1 514 AYGNLGNAYESLGDFQNAIEYHEKHLEIAK 543 9********************999998875 PP == domain 14 score: 19.1 bits; conditional E-value: 1.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd+ +A+ey ek le+ FUN_002337-T1 553 SAYGNLGNTYQSLGDFRKAIEYHEKDLEI 581 59********************8886666 PP == domain 15 score: 15.8 bits; conditional E-value: 2.1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG +y++lgd+ +A+ey ek le+ FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEKDLEI 621 8********************8886666 PP == domain 16 score: 16.9 bits; conditional E-value: 9.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002337-T1 634 AYGSLGNAYQSLGDFRKAIEYHEKHLEI 661 89*******************9987776 PP == domain 17 score: 11.1 bits; conditional E-value: 0.00069 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 ay lG++y++lgd+ +A+ y ek FUN_002337-T1 674 AYGSLGNAYQSLGDFRKAIGYHEK 697 89****************966555 PP == domain 18 score: 18.1 bits; conditional E-value: 4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002337-T1 714 AYGSLGNAYESLGDFRKAIEYHEKHLEIAK 743 89*******************999998875 PP == domain 19 score: 16.2 bits; conditional E-value: 1.6e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lg++ +A+++ ek le+ FUN_002337-T1 754 AYGNLGNAYQSLGEFRKAIKCHEKHLEI 781 9********************8887776 PP == domain 20 score: 22.7 bits; conditional E-value: 1.3e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd eA+eyyek le+ FUN_002337-T1 794 AYGSLGNAYQSLGDVREAIEYYEKHLEI 821 89**********************8887 PP == domain 21 score: 16.9 bits; conditional E-value: 9.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002337-T1 834 AYGSLGNAYQSLGDFRKAIEYHEKHLEI 861 89*******************9987776 PP == domain 22 score: 3.9 bits; conditional E-value: 0.14 TPR_8 4 yynlGliylklgdyeeA 20 ++n+G+ y +lg++e+A FUN_002337-T1 875 HHNIGHGYFSLGQFENA 891 79*************98 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.2 0.99 7.4e+02 2 23 .. 33 54 .. 32 60 .. 0.82 2 ! 8.3 0.2 0.0053 4 3 23 .. 74 94 .. 72 102 .. 0.91 3 ! 13.9 0.2 8.7e-05 0.066 3 23 .. 114 134 .. 112 141 .. 0.92 4 ! 16.5 0.3 1.3e-05 0.0096 3 23 .. 154 174 .. 152 182 .. 0.92 5 ! 10.6 0.1 0.00099 0.74 7 23 .. 198 214 .. 193 221 .. 0.92 6 ! 14.5 0.3 5.4e-05 0.041 3 23 .. 234 254 .. 232 264 .. 0.89 7 ! 14.1 0.3 7.6e-05 0.057 3 23 .. 274 294 .. 272 294 .. 0.94 8 ! 12.0 0.1 0.00034 0.25 3 23 .. 314 334 .. 312 341 .. 0.93 9 ! 12.5 0.3 0.00024 0.18 3 23 .. 354 374 .. 352 381 .. 0.91 10 ! 12.9 0.2 0.00017 0.13 3 23 .. 394 414 .. 392 424 .. 0.89 11 ! 14.8 0.2 4.3e-05 0.032 3 23 .. 434 454 .. 432 464 .. 0.89 12 ! 16.6 0.3 1.1e-05 0.0085 3 23 .. 474 494 .. 472 504 .. 0.89 13 ! 14.3 0.4 6.2e-05 0.047 3 23 .. 514 534 .. 512 544 .. 0.89 14 ! 14.3 0.1 6.3e-05 0.048 3 31 .. 554 582 .. 552 584 .. 0.87 15 ! 14.1 0.2 7.2e-05 0.054 3 31 .. 594 622 .. 592 624 .. 0.87 16 ! 11.8 0.2 0.00041 0.31 3 23 .. 634 654 .. 632 662 .. 0.90 17 ! 9.1 0.1 0.0031 2.3 3 23 .. 674 694 .. 672 701 .. 0.90 18 ! 12.1 0.3 0.00032 0.24 3 23 .. 714 734 .. 712 744 .. 0.87 19 ! 13.2 0.2 0.00014 0.11 3 23 .. 754 774 .. 752 782 .. 0.91 20 ! 17.8 0.2 4.8e-06 0.0036 3 28 .. 794 819 .. 792 823 .. 0.88 21 ! 11.8 0.2 0.00041 0.31 3 23 .. 834 854 .. 832 862 .. 0.90 22 ? 4.2 0.0 0.11 82 4 20 .. 875 891 .. 873 903 .. 0.86 23 ? -0.7 0.0 4.2 3.1e+03 10 26 .. 933 949 .. 932 952 .. 0.84 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.99 TPR_2 2 ealynlGlayyklgdyeeAlea 23 a+ + + a +g + +A+e+ FUN_002337-T1 33 NAYGYTSIAFHSQGYFRKAIEY 54 6777888888999999999987 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0053 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nl+ a lgd+ +A+++ FUN_002337-T1 74 GYQNLAHAFQSLGDFRKAIKY 94 799****************98 PP == domain 3 score: 13.9 bits; conditional E-value: 8.7e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002337-T1 114 AYGNLGNAYKSLGDFRKAIEY 134 899****************98 PP == domain 4 score: 16.5 bits; conditional E-value: 1.3e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEY 174 89*****************98 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00099 TPR_2 7 lGlayyklgdyeeAlea 23 lG+ay+ lgd+ +A+e+ FUN_002337-T1 198 LGNAYRSLGDFRKAIEY 214 9**************98 PP == domain 6 score: 14.5 bits; conditional E-value: 5.4e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002337-T1 234 AYGNLGNAYQSLGDFRKAIEY 254 899*****************9 PP == domain 7 score: 14.1 bits; conditional E-value: 7.6e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002337-T1 274 AYGNLGNAYQSLGDFRKAIEY 294 899****************98 PP == domain 8 score: 12.0 bits; conditional E-value: 0.00034 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+ +A+e+ FUN_002337-T1 314 AYGNLGIAYDSLGDFRKAIEY 334 899****************98 PP == domain 9 score: 12.5 bits; conditional E-value: 0.00024 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002337-T1 354 AYASLGNAYQSLGDFRKAIEY 374 8999***************98 PP == domain 10 score: 12.9 bits; conditional E-value: 0.00017 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+ +A+e+ FUN_002337-T1 394 AYGNLGIAYHSLGDFRKAIEY 414 899*****************9 PP == domain 11 score: 14.8 bits; conditional E-value: 4.3e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002337-T1 434 AYGNLGNAYESLGDFRKAIEY 454 899*****************9 PP == domain 12 score: 16.6 bits; conditional E-value: 1.1e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+++A+e+ FUN_002337-T1 474 AYGNLGNAYESLGDFQKAIEY 494 899*****************9 PP == domain 13 score: 14.3 bits; conditional E-value: 6.2e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd++ A+e+ FUN_002337-T1 514 AYGNLGNAYESLGDFQNAIEY 534 899*****************8 PP == domain 14 score: 14.3 bits; conditional E-value: 6.3e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG+ y lgd+ +A+e+ ek le++ FUN_002337-T1 554 AYGNLGNTYQSLGDFRKAIEYHEKDLEIA 582 899*****************977777765 PP == domain 15 score: 14.1 bits; conditional E-value: 7.2e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG ay lgd+ +A+e+ ek le++ FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEKDLEIA 622 799*****************977777765 PP == domain 16 score: 11.8 bits; conditional E-value: 0.00041 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002337-T1 634 AYGSLGNAYQSLGDFRKAIEY 654 7888***************98 PP == domain 17 score: 9.1 bits; conditional E-value: 0.0031 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+ + FUN_002337-T1 674 AYGSLGNAYQSLGDFRKAIGY 694 7888**************965 PP == domain 18 score: 12.1 bits; conditional E-value: 0.00032 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002337-T1 714 AYGSLGNAYESLGDFRKAIEY 734 7788****************8 PP == domain 19 score: 13.2 bits; conditional E-value: 0.00014 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lg++ +A+++ FUN_002337-T1 754 AYGNLGNAYQSLGEFRKAIKC 774 899****************98 PP == domain 20 score: 17.8 bits; conditional E-value: 4.8e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAl 28 a+ lG+ay lgd eA+e+yek l FUN_002337-T1 794 AYGSLGNAYQSLGDVREAIEYYEKHL 819 7888*******************955 PP == domain 21 score: 11.8 bits; conditional E-value: 0.00041 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002337-T1 834 AYGSLGNAYQSLGDFRKAIEY 854 7888***************98 PP == domain 22 score: 4.2 bits; conditional E-value: 0.11 TPR_2 4 lynlGlayyklgdyeeA 20 ++n G y+ lg++e A FUN_002337-T1 875 HHNIGHGYFSLGQFENA 891 89*************98 PP == domain 23 score: -0.7 bits; conditional E-value: 4.2 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002337-T1 933 SLLRIGKIDEALFAADE 949 67899*******98776 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.2 0.0 1.8e-54 1.3e-51 8 291 .] 1089 1351 .. 1084 1351 .. 0.89 Alignments for each domain: == domain 1 score: 176.2 bits; conditional E-value: 1.8e-54 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ ++Lviv dgaL +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ ++ k FUN_002337-T1 1089 YDAVIGPIEDLL-GPEDEELVIVSDGALCFIPWAAVIESIR---------IRIVPSLKSyqlISSVPEGYHKKTGA--LLVGNPCTKQ----LK 1166 899****99997.78888*****************988863.........55556654422266666666666666..*******885....47 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 +++lp +++E++++a++l++ ++l+g++at+ ++++ + ++++++H+a+Hg + ++L++ n + ed +L++++++ FUN_002337-T1 1167 KPLEPLPCAQKEVEMIAAILNT---RPLIGKEATKAEVMKRM-SSVGLIHIAAHGDEV-----TGQIALSP-NPGwtqfpkeEDYVLKMSDVQA 1250 777*****************88...8***************9.************999.....88899974.4445889999************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002337-T1 1251 ANLR-ARLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATMEFMKRFYQHLKDGKTASAAVHQSMKSLRESEE----FSE 1339 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002337-T1 1340 MWYWAPFQLIGD 1351 ***********7 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 9.6 7.2e+03 10 29 .. 41 60 .. 33 64 .. 0.84 2 ? 5.7 0.0 0.058 44 4 29 .. 75 100 .. 72 104 .. 0.89 3 ? 6.1 0.0 0.044 33 6 29 .. 117 140 .. 113 142 .. 0.87 4 ! 9.2 0.1 0.0043 3.2 3 29 .. 154 180 .. 153 182 .. 0.90 5 ? 7.4 0.1 0.017 13 6 29 .. 197 220 .. 193 224 .. 0.88 6 ? 6.5 0.0 0.031 24 6 32 .. 237 263 .. 233 268 .. 0.86 7 ? 4.2 0.0 0.18 1.3e+02 6 28 .. 277 299 .. 273 302 .. 0.83 8 ? 3.2 0.0 0.38 2.9e+02 6 29 .. 317 340 .. 313 342 .. 0.85 9 ! 8.1 0.0 0.0098 7.3 2 29 .. 353 380 .. 352 382 .. 0.90 10 ? 4.5 0.0 0.14 1.1e+02 7 30 .. 398 421 .. 393 426 .. 0.86 11 ! 8.3 0.0 0.0082 6.2 6 30 .. 437 461 .. 433 467 .. 0.87 12 ! 9.0 0.0 0.0051 3.8 6 31 .. 477 502 .. 473 507 .. 0.87 13 ? 7.4 0.0 0.017 12 6 30 .. 517 541 .. 513 546 .. 0.86 14 ? 1.7 0.0 1.1 8.6e+02 7 25 .. 558 576 .. 553 577 .. 0.86 15 ? 1.5 0.0 1.3 9.8e+02 7 25 .. 598 616 .. 593 617 .. 0.85 16 ? 5.9 0.0 0.049 37 5 29 .. 636 660 .. 633 662 .. 0.86 17 ? 3.5 0.0 0.31 2.3e+02 5 29 .. 676 700 .. 673 702 .. 0.85 18 ! 9.2 0.0 0.0043 3.2 3 31 .. 714 742 .. 712 747 .. 0.86 19 ? 3.7 0.0 0.26 2e+02 6 29 .. 757 780 .. 753 783 .. 0.85 20 ! 9.1 0.1 0.0047 3.6 5 29 .. 796 820 .. 793 822 .. 0.88 21 ? 5.9 0.0 0.049 37 5 29 .. 836 860 .. 833 862 .. 0.86 22 ? 3.2 0.1 0.37 2.8e+02 10 41 .. 933 965 .. 931 967 .. 0.75 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 9.6 TPR_14 10 allalGdpdeAlellerala 29 a+ +G + +A+e+ e+ l+ FUN_002337-T1 41 AFHSQGYFRKAIEYHEKHLK 60 56789*********999877 PP == domain 2 score: 5.7 bits; conditional E-value: 0.058 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ la+a+ lGd+ +A+++ e+ l+ FUN_002337-T1 75 YQNLAHAFQSLGDFRKAIKYHEKHLK 100 7889****************999887 PP == domain 3 score: 6.1 bits; conditional E-value: 0.044 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 117 NLGNAYKSLGDFRKAIEYHEKHLK 140 689***************999876 PP == domain 4 score: 9.2 bits; conditional E-value: 0.0043 TPR_14 3 awlalarallalGdpdeAlellerala 29 a++ l++a++ lGd+ +A+e+ e+ l+ FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEYHEKHLE 180 7899*****************998876 PP == domain 5 score: 7.4 bits; conditional E-value: 0.017 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002337-T1 197 SLGNAYRSLGDFRKAIEYHEKHLE 220 589***************999887 PP == domain 6 score: 6.5 bits; conditional E-value: 0.031 TPR_14 6 alarallalGdpdeAlelleralaldP 32 l++a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 237 NLGNAYQSLGDFRKAIEYHEKHLEIAK 263 5899****************9998765 PP == domain 7 score: 4.2 bits; conditional E-value: 0.18 TPR_14 6 alarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002337-T1 277 NLGNAYQSLGDFRKAIEYHAKHL 299 689**************987766 PP == domain 8 score: 3.2 bits; conditional E-value: 0.38 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 317 NLGIAYDSLGDFRKAIEYHEKHLE 340 578899************998876 PP == domain 9 score: 8.1 bits; conditional E-value: 0.0098 TPR_14 2 eawlalarallalGdpdeAlellerala 29 +a++ l++a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 353 NAYASLGNAYQSLGDFRKAIEYHEKHLE 380 58999*****************998876 PP == domain 10 score: 4.5 bits; conditional E-value: 0.14 TPR_14 7 larallalGdpdeAlelleralal 30 l+ a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 398 LGIAYHSLGDFRKAIEYHEKHLEI 421 7889*************9999886 PP == domain 11 score: 8.3 bits; conditional E-value: 0.0082 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a++ lGd+ +A+e+ e+ l+ FUN_002337-T1 437 NLGNAYESLGDFRKAIEYHEKHLEI 461 589***************9999886 PP == domain 12 score: 9.0 bits; conditional E-value: 0.0051 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a++ lGd+++A+e+ e+ l+ FUN_002337-T1 477 NLGNAYESLGDFQKAIEYHEKHLEIA 502 589***************99998865 PP == domain 13 score: 7.4 bits; conditional E-value: 0.017 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a++ lGd++ A+e+ e+ l+ FUN_002337-T1 517 NLGNAYESLGDFQNAIEYHEKHLEI 541 699***************9999886 PP == domain 14 score: 1.7 bits; conditional E-value: 1.1 TPR_14 7 larallalGdpdeAlelle 25 l++++ lGd+ +A+e+ e FUN_002337-T1 558 LGNTYQSLGDFRKAIEYHE 576 8999***********9866 PP == domain 15 score: 1.5 bits; conditional E-value: 1.3 TPR_14 7 larallalGdpdeAlelle 25 l+ a+ lGd+ +A+e+ e FUN_002337-T1 598 LGIAYQSLGDFRKAIEYHE 616 7889***********9866 PP == domain 16 score: 5.9 bits; conditional E-value: 0.049 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 636 GSLGNAYQSLGDFRKAIEYHEKHLE 660 5799***************998876 PP == domain 17 score: 3.5 bits; conditional E-value: 0.31 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+ + e+ l+ FUN_002337-T1 676 GSLGNAYQSLGDFRKAIGYHEKHLE 700 5799*************99988776 PP == domain 18 score: 9.2 bits; conditional E-value: 0.0043 TPR_14 3 awlalarallalGdpdeAlelleralald 31 a+ l++a++ lGd+ +A+e+ e+ l+ FUN_002337-T1 714 AYGSLGNAYESLGDFRKAIEYHEKHLEIA 742 56679****************99998865 PP == domain 19 score: 3.7 bits; conditional E-value: 0.26 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lG++ +A+++ e+ l+ FUN_002337-T1 757 NLGNAYQSLGEFRKAIKCHEKHLE 780 689**************9998776 PP == domain 20 score: 9.1 bits; conditional E-value: 0.0047 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd eA+e++e+ l+ FUN_002337-T1 796 GSLGNAYQSLGDVREAIEYYEKHLE 820 5799*****************9887 PP == domain 21 score: 5.9 bits; conditional E-value: 0.049 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002337-T1 836 GSLGNAYQSLGDFRKAIEYHEKHLE 860 5799***************998876 PP == domain 22 score: 3.2 bits; conditional E-value: 0.37 TPR_14 10 allalGdpdeAlelleralal.dPddpeawlal 41 ll+ G+ deAl +++++ a+ d+ +++++l FUN_002337-T1 933 SLLRIGKIDEALFAADEGRAQtLSDNLWIQYKL 965 6899**************776234555555555 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.33 2.5e+02 15 33 .. 74 92 .. 72 93 .. 0.91 2 ! 8.1 0.1 0.0069 5.2 14 34 .] 113 133 .. 111 133 .. 0.93 3 ? 6.7 0.0 0.02 15 15 34 .] 154 173 .. 151 173 .. 0.92 4 ? 2.0 0.0 0.62 4.7e+02 16 34 .] 195 213 .. 192 213 .. 0.87 5 ! 7.6 0.1 0.0095 7.1 14 34 .] 233 253 .. 231 253 .. 0.92 6 ! 8.2 0.1 0.0062 4.6 14 34 .] 273 293 .. 271 293 .. 0.93 7 ? 6.9 0.0 0.016 12 14 34 .] 313 333 .. 311 333 .. 0.93 8 ? 5.8 0.1 0.037 28 14 34 .] 353 373 .. 351 373 .. 0.92 9 ! 7.8 0.0 0.0082 6.2 14 34 .] 393 413 .. 391 413 .. 0.92 10 ! 7.7 0.0 0.0091 6.8 14 34 .] 433 453 .. 431 453 .. 0.92 11 ! 9.2 0.1 0.0029 2.2 14 34 .] 473 493 .. 471 493 .. 0.92 12 ? 7.2 0.1 0.014 10 14 33 .. 513 532 .. 511 533 .. 0.91 13 ! 8.4 0.0 0.0056 4.2 14 34 .] 553 573 .. 551 573 .. 0.92 14 ? 6.4 0.0 0.023 17 15 34 .] 594 613 .. 592 613 .. 0.93 15 ? 5.3 0.1 0.052 39 14 34 .] 633 653 .. 631 653 .. 0.92 16 ? 4.5 0.1 0.098 74 14 33 .. 673 692 .. 671 693 .. 0.92 17 ? 5.0 0.0 0.066 50 14 34 .] 713 733 .. 712 733 .. 0.92 18 ? 7.1 0.1 0.014 10 14 33 .. 753 772 .. 751 773 .. 0.92 19 ? 5.0 0.0 0.067 50 14 34 .] 793 813 .. 791 813 .. 0.92 20 ? 5.3 0.1 0.052 39 14 34 .] 833 853 .. 831 853 .. 0.92 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.33 TPR_17 15 ayynLArlllnnGqleeAl 33 y+nLA++ + +G++ +A+ FUN_002337-T1 74 GYQNLAHAFQSLGDFRKAI 92 69**************998 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0069 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002337-T1 113 NAYGNLGNAYKSLGDFRKAIE 133 79****************985 PP == domain 3 score: 6.7 bits; conditional E-value: 0.02 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIE 173 899**************985 PP == domain 4 score: 2.0 bits; conditional E-value: 0.62 TPR_17 16 yynLArlllnnGqleeAlq 34 L+++++ +G++ +A++ FUN_002337-T1 195 RGSLGNAYRSLGDFRKAIE 213 5689************985 PP == domain 5 score: 7.6 bits; conditional E-value: 0.0095 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002337-T1 233 SAYGNLGNAYQSLGDFRKAIE 253 59****************985 PP == domain 6 score: 8.2 bits; conditional E-value: 0.0062 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002337-T1 273 NAYGNLGNAYQSLGDFRKAIE 293 79****************985 PP == domain 7 score: 6.9 bits; conditional E-value: 0.016 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL++++ +G++ +A++ FUN_002337-T1 313 NAYGNLGIAYDSLGDFRKAIE 333 79****************985 PP == domain 8 score: 5.8 bits; conditional E-value: 0.037 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002337-T1 353 NAYASLGNAYQSLGDFRKAIE 373 79****************985 PP == domain 9 score: 7.8 bits; conditional E-value: 0.0082 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002337-T1 393 SAYGNLGIAYHSLGDFRKAIE 413 59****************985 PP == domain 10 score: 7.7 bits; conditional E-value: 0.0091 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002337-T1 433 SAYGNLGNAYESLGDFRKAIE 453 59****************985 PP == domain 11 score: 9.2 bits; conditional E-value: 0.0029 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++++A++ FUN_002337-T1 473 SAYGNLGNAYESLGDFQKAIE 493 59*****************85 PP == domain 12 score: 7.2 bits; conditional E-value: 0.014 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay nL+++++ +G+++ A+ FUN_002337-T1 513 NAYGNLGNAYESLGDFQNAI 532 79**************9997 PP == domain 13 score: 8.4 bits; conditional E-value: 0.0056 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002337-T1 553 SAYGNLGNTYQSLGDFRKAIE 573 59****************985 PP == domain 14 score: 6.4 bits; conditional E-value: 0.023 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIE 613 89***************985 PP == domain 15 score: 5.3 bits; conditional E-value: 0.052 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002337-T1 633 NAYGSLGNAYQSLGDFRKAIE 653 79****************985 PP == domain 16 score: 4.5 bits; conditional E-value: 0.098 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay L+++++ +G++ +A+ FUN_002337-T1 673 NAYGSLGNAYQSLGDFRKAI 692 79**************9997 PP == domain 17 score: 5.0 bits; conditional E-value: 0.066 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002337-T1 713 NAYGSLGNAYESLGDFRKAIE 733 699***************985 PP == domain 18 score: 7.1 bits; conditional E-value: 0.014 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay nL+++++ +G++ +A+ FUN_002337-T1 753 NAYGNLGNAYQSLGEFRKAI 772 79***************998 PP == domain 19 score: 5.0 bits; conditional E-value: 0.067 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G+ eA++ FUN_002337-T1 793 NAYGSLGNAYQSLGDVREAIE 813 79****************985 PP == domain 20 score: 5.3 bits; conditional E-value: 0.052 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002337-T1 833 NAYGSLGNAYQSLGDFRKAIE 853 79****************985 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.24 1.8e+02 46 78 .. 35 67 .. 27 69 .. 0.87 2 ? 3.5 0.4 0.14 1.1e+02 31 75 .. 57 104 .. 50 108 .. 0.66 3 ? 6.4 0.2 0.018 13 39 76 .. 108 145 .. 87 148 .. 0.75 4 ? 3.7 0.0 0.13 95 50 76 .. 159 185 .. 150 188 .. 0.85 5 ? 6.0 0.0 0.023 17 44 76 .. 193 225 .. 186 229 .. 0.88 6 ! 7.6 0.1 0.0072 5.4 46 77 .. 235 266 .. 226 268 .. 0.89 7 ! 8.1 0.0 0.0051 3.8 35 76 .. 264 305 .. 263 309 .. 0.90 8 ? 4.0 0.0 0.097 73 46 76 .. 315 345 .. 306 348 .. 0.87 9 ? 4.9 0.0 0.051 38 49 78 .. 358 387 .. 352 389 .. 0.88 10 ! 7.2 0.1 0.0098 7.4 46 76 .. 395 425 .. 384 428 .. 0.85 11 ? 6.8 0.0 0.013 9.9 39 78 .. 428 467 .. 423 468 .. 0.83 12 ! 11.3 0.0 0.00051 0.39 33 78 .. 462 507 .. 459 509 .. 0.93 13 ! 7.6 0.0 0.0072 5.4 38 77 .. 507 546 .. 505 549 .. 0.87 14 ? 7.0 0.0 0.011 8.6 47 78 .. 556 587 .. 546 589 .. 0.86 15 ! 7.3 0.0 0.0092 6.9 46 76 .. 595 625 .. 586 629 .. 0.85 16 ? 6.0 0.0 0.024 18 46 76 .. 635 665 .. 627 668 .. 0.88 17 ? 3.6 0.0 0.13 97 45 76 .. 674 705 .. 664 708 .. 0.87 18 ! 8.9 0.0 0.0029 2.2 46 78 .. 715 747 .. 706 749 .. 0.90 19 ? 3.2 0.0 0.17 1.3e+02 35 74 .. 744 783 .. 743 787 .. 0.86 20 ? 4.2 0.0 0.085 64 46 76 .. 795 825 .. 786 828 .. 0.88 21 ? 6.0 0.0 0.024 18 46 76 .. 835 865 .. 826 868 .. 0.88 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.24 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 Gy a G ++ a+e+ + l i+ e+ d FUN_002337-T1 35 YGYTSIAFHSQGYFRKAIEYHEKHLKITMEVGD 67 58888899999****************999865 PP == domain 2 score: 3.5 bits; conditional E-value: 0.14 Rapsyn_N 31 kvlkktsdredkf.rllGy..litahsemGkykealefslaqlniaee 75 k lk t + +d+ + Gy l a +G ++ a+++ + l ia e FUN_002337-T1 57 KHLKITMEVGDRAgEEKGYqnLAHAFQSLGDFRKAIKYHEKHLKIAIE 104 5555555444432123344116777789*************9999977 PP == domain 3 score: 6.4 bits; conditional E-value: 0.018 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaeel 76 r + + G l +a+ +G ++ a+e+ + l ia e+ FUN_002337-T1 108 RVGEGNAYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEV 145 445556789999*********************99886 PP == domain 4 score: 3.7 bits; conditional E-value: 0.13 Rapsyn_N 50 itahsemGkykealefslaqlniaeel 76 +a+ +G ++ a+e+ + l+ia e+ FUN_002337-T1 159 GNAYRSLGDFRKAIEYHEKHLEIAIEV 185 468889*****************9886 PP == domain 5 score: 6.0 bits; conditional E-value: 0.023 Rapsyn_N 44 rllGylitahsemGkykealefslaqlniaeel 76 r G l +a+ +G ++ a+e+ + l+ia e+ FUN_002337-T1 193 RARGSLGNAYRSLGDFRKAIEYHEKHLEIAVEV 225 56699999*********************9986 PP == domain 6 score: 7.6 bits; conditional E-value: 0.0072 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l+ia+e FUN_002337-T1 235 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEAS 266 588999***********************976 PP == domain 7 score: 8.1 bits; conditional E-value: 0.0051 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 ++sdr + + G l +a+ +G ++ a+e+ + l+ia e+ FUN_002337-T1 264 EASDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEV 305 678888888999**************************9887 PP == domain 8 score: 4.0 bits; conditional E-value: 0.097 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G ++ a+e+ + l+ia e+ FUN_002337-T1 315 YGNLGIAYDSLGDFRKAIEYHEKHLEIAIEV 345 5778889999*****************9886 PP == domain 9 score: 4.9 bits; conditional E-value: 0.051 Rapsyn_N 49 litahsemGkykealefslaqlniaeeled 78 l +a+ +G ++ a+e+ + l+ia e+ d FUN_002337-T1 358 LGNAYQSLGDFRKAIEYHEKHLEIAIEVSD 387 5578899******************99876 PP == domain 10 score: 7.2 bits; conditional E-value: 0.0098 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G ++ a+e+ + l+ia+e+ FUN_002337-T1 395 YGNLGIAYHSLGDFRKAIEYHEKHLEIAKEV 425 6788889999*******************98 PP == domain 11 score: 6.8 bits; conditional E-value: 0.013 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaeeled 78 r + G l +a+ +G ++ a+e+ + l+ia+ + d FUN_002337-T1 428 RVGEGSAYGNLGNAYESLGDFRKAIEYHEKHLEIAKKVSD 467 555556679999***********************98765 PP == domain 12 score: 11.3 bits; conditional E-value: 0.00051 Rapsyn_N 33 lkktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 kk sdr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002337-T1 462 AKKVSDRVGEGSAYGNLGNAYESLGDFQKAIEYHEKHLEIAKEVSD 507 68999999999********************************976 PP == domain 13 score: 7.6 bits; conditional E-value: 0.0072 Rapsyn_N 38 dredkfrllGylitahsemGkykealefslaqlniaeele 77 dr + + G l +a+ +G +++a+e+ + l+ia+e+ FUN_002337-T1 507 DRVGEGNAYGNLGNAYESLGDFQNAIEYHEKHLEIAKEVS 546 5566666789999************************985 PP == domain 14 score: 7.0 bits; conditional E-value: 0.011 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeeled 78 G l +++ +G ++ a+e+ + l+ia+e+ d FUN_002337-T1 556 GNLGNTYQSLGDFRKAIEYHEKDLEIAKEVSD 587 777788889********************976 PP == domain 15 score: 7.3 bits; conditional E-value: 0.0092 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G ++ a+e+ + l+ia+e+ FUN_002337-T1 595 YGNLGIAYQSLGDFRKAIEYHEKDLEIAKEV 625 5777789999*******************97 PP == domain 16 score: 6.0 bits; conditional E-value: 0.024 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002337-T1 635 YGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 665 688999*********************9886 PP == domain 17 score: 3.6 bits; conditional E-value: 0.13 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+ + + l+ia e+ FUN_002337-T1 674 AYGSLGNAYQSLGDFRKAIGYHEKHLEIAIEV 705 5689999*********************9886 PP == domain 18 score: 8.9 bits; conditional E-value: 0.0029 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002337-T1 715 YGSLGNAYESLGDFRKAIEYHEKHLEIAKEVSD 747 688999************************976 PP == domain 19 score: 3.2 bits; conditional E-value: 0.17 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniae 74 + sdr + + G l +a+ +G ++ a++ + l+ia FUN_002337-T1 744 EVSDRVGEGNAYGNLGNAYQSLGEFRKAIKCHEKHLEIAI 783 5678888888899*****************9999999885 PP == domain 20 score: 4.2 bits; conditional E-value: 0.085 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G +ea+e+ + l+ia e+ FUN_002337-T1 795 YGSLGNAYQSLGDVREAIEYYEKHLEIAIEV 825 688999*********************9886 PP == domain 21 score: 6.0 bits; conditional E-value: 0.024 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002337-T1 835 YGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 865 688999*********************9886 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.1 5.4e-06 0.0041 9 191 .. 80 262 .. 76 264 .. 0.89 2 ! 12.1 0.1 0.00016 0.12 13 150 .. 204 340 .. 198 377 .. 0.65 3 ! 15.6 0.0 1.4e-05 0.011 11 112 .. 402 504 .. 397 509 .. 0.92 4 ! 21.8 0.0 1.8e-07 0.00013 13 186 .. 484 657 .. 479 662 .. 0.90 5 ! 9.4 0.0 0.0011 0.8 42 149 .. 594 703 .. 585 714 .. 0.75 6 ! 8.5 0.0 0.002 1.5 15 130 .. 646 760 .. 644 788 .. 0.74 7 ! 16.2 0.1 8.8e-06 0.0066 13 155 .. 724 865 .. 719 891 .. 0.87 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 5.4e-06 TPR_MalT 9 llavsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaety 103 + s g++ +a+++ ++ L++ e + + + a+ +lG a+ +gd+ +A + ++ ++a + ++ a++ +++ +r G++++A+e FUN_002337-T1 80 HAFQSLGDFRKAIKYHEKHLKIAIEAGHRVGeGNAYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEVGHRVGEGSAYRNLGNAYRSLGDFRKAIEYH 175 556678999999999999999999999999889*****************9999999999999999999999************************ PP TPR_MalT 104 qqalqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerla 191 ++ l+ a e + + g + +l++ ++ +d+ +A ++ ++ ++++ ++ + ay l + ++ G+ + A ++ ++ ++a FUN_002337-T1 176 EKHLEIAIEVGNRV--GEGRARGSLGNAYRSLGDFRKAIEYHEKHLEIAVEVgHRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIA 262 **********9996..88899999******************99999999985668888888888888888888888888877766655 PP == domain 2 score: 12.1 bits; conditional E-value: 0.00016 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + ++a+ +lG a++ +gd+ +A + ++ ++a++a + a+ +++ ++ G++++A+e + l FUN_002337-T1 204 SLGDFRKAIEYHEKHLEIAVEVGHRVGeGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEASDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHL 299 567788888888888888888777776688888888888888888888888888888888888887788888888888888888888888887777 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiq 150 + a e + + g ++ l+ + +d+ +A ++ ++ ++ FUN_002337-T1 300 EIAIEVGNRV--GEGNAYGNLGIAYDSLGDFRKAIEYHEKHLE 340 7777766553..4444444444444444444444444444444 PP == domain 3 score: 15.6 bits; conditional E-value: 1.4e-05 TPR_MalT 11 avsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 + s g++ +a+e+ ++ L++ +e ++ + ++a+ +lG a+ +gd+ +A + ++ ++a++ + a+ +++ ++ G++++A+e ++ FUN_002337-T1 402 YHSLGDFRKAIEYHEKHLEIAKEVSHRVGeGSAYGNLGNAYESLGDFRKAIEYHEKHLEIAKKVSDRVGEGSAYGNLGNAYESLGDFQKAIEYHEK 497 567899*******************99988******************9999999999999999888889999*********************** PP TPR_MalT 106 alqlaqe 112 l+ a+e FUN_002337-T1 498 HLEIAKE 504 9999987 PP == domain 4 score: 21.8 bits; conditional E-value: 1.8e-07 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++++a+e+ ++ L++ +e +d + a+ +lG a+ +gd+++A + ++ ++a++ + a+ ++++++ G++++A+e ++ l FUN_002337-T1 484 SLGDFQKAIEYHEKHLEIAKEvSDRVGEGNAYGNLGNAYESLGDFQNAIEYHEKHLEIAKEVSHRVGEGSAYGNLGNTYQSLGDFRKAIEYHEKDL 579 67999*************98834445559999******************9999999999999999999*************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqr 186 + a+e + + g+++ l+ + +d+ +A ++ ++ +++++++ ++ +ay l + ++ G+ + A ++ ++ FUN_002337-T1 580 EIAKEVSDRV--GEGGAYGNLGIAYQSLGDFRKAIEYHEKDLEIAKEVgNRVGEGNAYGSLGNAYQSLGDFRKAIEYHEK 657 *****99995..8899*******************************956688899999999999999999999887766 PP == domain 5 score: 9.4 bits; conditional E-value: 0.0011 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 a+ +lG a++ +gd+ +A + ++ ++a++ ++ a+ ++++ ++ G++++A+e ++ l+ a e + + g ++ +l++ + +d FUN_002337-T1 594 AYGNLGIAYQSLGDFRKAIEYHEKDLEIAKEVGNRVGEGNAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNRV--GQGNAYGSLGNAYQSLGD 687 5688899999999999999988888889999988888889999999999999999999999999999988888774..777777777777777777 PP TPR_MalT 138 LeeA....eqhlqqgi 149 + +A e+hl+ +i FUN_002337-T1 688 FRKAigyhEKHLEIAI 703 7777444444444444 PP == domain 6 score: 8.5 bits; conditional E-value: 0.002 TPR_MalT 15 geaeeaeelAreALall.peddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 g++ +a+e+ ++ L++ + + ++ a+ +lG a++ +gd+ +A ++ ++a + ++ a+ ++++ ++ G++++A+e ++ l+ FUN_002337-T1 646 GDFRKAIEYHEKHLEIAiEVGNRVGQGNAYGSLGNAYQSLGDFRKAIGYHEKHLEIAIEVGHRVGEENAYGSLGNAYESLGDFRKAIEYHEKHLEI 741 566666666666666641334445578899999999999999999999999999999988888889999999999999999999999999999999 PP TPR_MalT 110 aqesklealplvgfllvglad 130 a+e + + g ++ l++ FUN_002337-T1 742 AKEVSDRV--GEGNAYGNLGN 760 99877663..44455555555 PP == domain 7 score: 16.2 bits; conditional E-value: 8.8e-06 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ +e +d + a+ +lG a++ +g++ +A + ++ ++a + ++ a+ ++++ ++ G+ ++A+e y++ l FUN_002337-T1 724 SLGDFRKAIEYHEKHLEIAKEvSDRVGEGNAYGNLGNAYQSLGEFRKAIKCHEKHLEIAIDVGHRVGEGNAYGSLGNAYQSLGDVREAIEYYEKHL 819 56899999999999999998733444559999******************9999999999999999999*************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 + a e + + g ++ +l++ + +d+ +A ++ ++ ++++ ++ FUN_002337-T1 820 EIAIEVGHRV--GEGNAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEV 865 ****998884..888999999999999999999988777776665554 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.1 0.065 48 3 58 .. 78 139 .. 77 144 .. 0.77 2 ! 11.0 0.2 0.00088 0.66 3 59 .. 118 180 .. 110 185 .. 0.82 3 ! 12.2 0.3 0.00037 0.28 2 58 .. 157 219 .. 156 223 .. 0.86 4 ? 2.0 0.0 0.55 4.1e+02 3 19 .. 238 254 .. 237 257 .. 0.90 5 ! 8.4 0.1 0.0055 4.1 3 59 .. 278 340 .. 277 344 .. 0.85 6 ! 10.3 0.0 0.0014 1.1 3 59 .. 358 420 .. 356 425 .. 0.86 7 ! 11.9 0.3 0.00044 0.33 3 59 .. 438 500 .. 429 506 .. 0.78 8 ? 7.4 0.1 0.012 8.9 32 59 .. 513 540 .. 502 544 .. 0.85 9 ? 0.4 0.0 1.8 1.4e+03 3 19 .. 558 574 .. 552 581 .. 0.89 10 ? 0.8 0.0 1.3 9.8e+02 3 19 .. 598 614 .. 594 617 .. 0.88 11 ? 2.0 0.0 0.58 4.4e+02 3 19 .. 638 654 .. 631 665 .. 0.87 12 ? 7.1 0.1 0.015 11 3 59 .. 678 740 .. 677 744 .. 0.81 13 ! 10.2 0.0 0.0015 1.1 3 60 .. 758 821 .. 757 824 .. 0.83 14 ? 1.9 0.0 0.61 4.6e+02 3 19 .. 838 854 .. 831 861 .. 0.88 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.065 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 la+a+ +gd++ A+++ l+ a++++ A+ +lG a+ +g++ +A+++ ++ l FUN_002337-T1 78 LAHAFQSLGDFRKAIKYhekhLKIAIEAGhrVGEGNAYGNLGNAYKSLGDFRKAIEYHEKHL 139 78999999999999865333377888888996688999999999999999999998766655 PP == domain 2 score: 11.0 bits; conditional E-value: 0.00088 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ l+ a++ + A+++lG a+ +g++ +A+++ ++ l+ FUN_002337-T1 118 LGNAYKSLGDFRKAIEYhekhLKIAIEVGhrVGEGSAYRNLGNAYRSLGDFRKAIEYHEKHLE 180 78999999999999876333377777777**77999*******************99777665 PP == domain 3 score: 12.2 bits; conditional E-value: 0.00037 TPR_16 2 alaraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd++ A+++ le a++ + +A+ lG a+ +g++ +A+++ ++ l FUN_002337-T1 157 NLGNAYRSLGDFRKAIEYhekhLEIAIEVGnrVGEGRARGSLGNAYRSLGDFRKAIEYHEKHL 219 589************975444499999999**7799********************9866665 PP == domain 4 score: 2.0 bits; conditional E-value: 0.55 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002337-T1 238 LGNAYQSLGDFRKAIEY 254 89************986 PP == domain 5 score: 8.4 bits; conditional E-value: 0.0055 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l+ FUN_002337-T1 278 LGNAYQSLGDFRKAIEYhakhLEIAIEVGnrVGEGNAYGNLGIAYDSLGDFRKAIEYHEKHLE 340 899***********764444499999999**7799********************98776665 PP == domain 6 score: 10.3 bits; conditional E-value: 0.0014 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ le a++ A+ +lG a++ +g++ +A+++ ++ l+ FUN_002337-T1 358 LGNAYQSLGDFRKAIEYhekhLEIAIEVSdqVGEGSAYGNLGIAYHSLGDFRKAIEYHEKHLE 420 799***********975444499999999**77999*******************99777665 PP == domain 7 score: 11.9 bits; conditional E-value: 0.00044 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ e l+ A+ +lG a++ +g++++A+++ ++ l+ FUN_002337-T1 438 LGNAYESLGDFRKAIEYHEKHLEIAkkvsdrVGEGSAYGNLGNAYESLGDFQKAIEYHEKHLE 500 677777777777777766554444467789966899*******************99777765 PP == domain 8 score: 7.4 bits; conditional E-value: 0.012 TPR_16 32 aAllglGlallrqgrlaeAaaayraalr 59 A+ +lG a++ +g+++ A+++ ++ l+ FUN_002337-T1 513 NAYGNLGNAYESLGDFQNAIEYHEKHLE 540 68999***************99777665 PP == domain 9 score: 0.4 bits; conditional E-value: 1.8 TPR_16 3 laraalaagdyddAaaa 19 l++ + +gd++ A+++ FUN_002337-T1 558 LGNTYQSLGDFRKAIEY 574 78999999999999975 PP == domain 10 score: 0.8 bits; conditional E-value: 1.3 TPR_16 3 laraalaagdyddAaaa 19 l+ a+ +gd++ A+++ FUN_002337-T1 598 LGIAYQSLGDFRKAIEY 614 78999999****99985 PP == domain 11 score: 2.0 bits; conditional E-value: 0.58 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002337-T1 638 LGNAYQSLGDFRKAIEY 654 68999999999999875 PP == domain 12 score: 7.1 bits; conditional E-value: 0.015 TPR_16 3 laraalaagdyddAa....aaleaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+ + le a++ + A+ lG a++ +g++ +A+++ ++ l+ FUN_002337-T1 678 LGNAYQSLGDFRKAIgyheKHLEIAIEVGhrVGEENAYGSLGNAYESLGDFRKAIEYHEKHLE 740 789999999999997333357999999999944558*******************98777665 PP == domain 13 score: 10.2 bits; conditional E-value: 0.0015 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalra 60 l++a+ +g+++ A+++ le a++ + A+ lG a+ +g++ eA+++y++ l++ FUN_002337-T1 758 LGNAYQSLGEFRKAIKChekhLEIAIDVGhrVGEGNAYGSLGNAYQSLGDVREAIEYYEKHLEI 821 788999999999997543333999999999977899**********************999876 PP == domain 14 score: 1.9 bits; conditional E-value: 0.61 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002337-T1 838 LGNAYQSLGDFRKAIEY 854 78999999999999975 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.2 0.0 0.31 2.4e+02 5 22 .. 117 134 .. 114 136 .. 0.92 2 ? 5.0 0.0 0.084 63 2 22 .. 154 174 .. 153 176 .. 0.89 3 ? 3.0 0.0 0.37 2.8e+02 6 22 .. 198 214 .. 197 216 .. 0.93 4 ? 3.5 0.0 0.26 2e+02 5 22 .. 237 254 .. 234 256 .. 0.92 5 ? 3.4 0.0 0.27 2e+02 5 22 .. 277 294 .. 274 295 .. 0.92 6 ? 2.6 0.0 0.51 3.8e+02 6 22 .. 318 334 .. 317 336 .. 0.92 7 ? 2.7 0.1 0.47 3.5e+02 6 22 .. 358 374 .. 354 376 .. 0.92 8 ? 1.7 0.0 0.98 7.4e+02 6 22 .. 398 414 .. 395 416 .. 0.92 9 ? 3.9 0.0 0.2 1.5e+02 5 22 .. 437 454 .. 434 456 .. 0.92 10 ? 5.0 0.0 0.086 64 5 22 .. 477 494 .. 474 496 .. 0.92 11 ? 4.2 0.0 0.15 1.2e+02 6 22 .. 518 534 .. 515 536 .. 0.93 12 ? 2.4 0.0 0.59 4.4e+02 5 22 .. 557 574 .. 552 577 .. 0.75 13 ? 3.5 0.0 0.26 2e+02 6 22 .. 598 614 .. 597 616 .. 0.92 14 ? 2.6 0.0 0.5 3.7e+02 6 22 .. 638 654 .. 637 656 .. 0.93 15 ? 1.3 0.0 1.3 1e+03 6 21 .. 678 693 .. 677 694 .. 0.90 16 ? 3.0 0.0 0.38 2.8e+02 6 22 .. 718 734 .. 717 736 .. 0.93 17 ? 1.1 0.1 1.5 1.1e+03 5 21 .. 757 773 .. 754 774 .. 0.91 18 ! 8.1 0.0 0.0086 6.5 6 25 .. 798 817 .. 797 819 .. 0.95 19 ? 2.6 0.0 0.5 3.7e+02 6 22 .. 838 854 .. 837 856 .. 0.93 Alignments for each domain: == domain 1 score: 3.2 bits; conditional E-value: 0.31 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002337-T1 117 NLGNAYKSLGDFRKAIEY 134 589************986 PP == domain 2 score: 5.0 bits; conditional E-value: 0.084 TPR_6 2 AllklalsylelgdkdeAkaa 22 A+ +l+ +y+ lgd+ +A+++ FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEY 174 56689*************986 PP == domain 3 score: 3.0 bits; conditional E-value: 0.37 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002337-T1 198 LGNAYRSLGDFRKAIEY 214 799***********986 PP == domain 4 score: 3.5 bits; conditional E-value: 0.26 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002337-T1 237 NLGNAYQSLGDFRKAIEY 254 599************986 PP == domain 5 score: 3.4 bits; conditional E-value: 0.27 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002337-T1 277 NLGNAYQSLGDFRKAIEY 294 599************986 PP == domain 6 score: 2.6 bits; conditional E-value: 0.51 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002337-T1 318 LGIAYDSLGDFRKAIEY 334 89************986 PP == domain 7 score: 2.7 bits; conditional E-value: 0.47 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002337-T1 358 LGNAYQSLGDFRKAIEY 374 799***********986 PP == domain 8 score: 1.7 bits; conditional E-value: 0.98 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002337-T1 398 LGIAYHSLGDFRKAIEY 414 89************986 PP == domain 9 score: 3.9 bits; conditional E-value: 0.2 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002337-T1 437 NLGNAYESLGDFRKAIEY 454 599************986 PP == domain 10 score: 5.0 bits; conditional E-value: 0.086 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+++A+++ FUN_002337-T1 477 NLGNAYESLGDFQKAIEY 494 599************986 PP == domain 11 score: 4.2 bits; conditional E-value: 0.15 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002337-T1 518 LGNAYESLGDFQNAIEY 534 89************986 PP == domain 12 score: 2.4 bits; conditional E-value: 0.59 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ y+ lgd+ +A+++ FUN_002337-T1 557 NLGNTYQSLGDFRKAIEY 574 477888888888888775 PP == domain 13 score: 3.5 bits; conditional E-value: 0.26 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002337-T1 598 LGIAYQSLGDFRKAIEY 614 89************986 PP == domain 14 score: 2.6 bits; conditional E-value: 0.5 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002337-T1 638 LGNAYQSLGDFRKAIEY 654 799***********986 PP == domain 15 score: 1.3 bits; conditional E-value: 1.3 TPR_6 6 lalsylelgdkdeAka 21 l+ +y+ lgd+ +A+ FUN_002337-T1 678 LGNAYQSLGDFRKAIG 693 799***********86 PP == domain 16 score: 3.0 bits; conditional E-value: 0.38 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002337-T1 718 LGNAYESLGDFRKAIEY 734 799***********986 PP == domain 17 score: 1.1 bits; conditional E-value: 1.5 TPR_6 5 klalsylelgdkdeAka 21 +l+ +y+ lg++ +A++ FUN_002337-T1 757 NLGNAYQSLGEFRKAIK 773 589************97 PP == domain 18 score: 8.1 bits; conditional E-value: 0.0086 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd eA++++++ FUN_002337-T1 798 LGNAYQSLGDVREAIEYYEK 817 799***************97 PP == domain 19 score: 2.6 bits; conditional E-value: 0.5 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002337-T1 838 LGNAYQSLGDFRKAIEY 854 799***********986 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 6.2 4.7e+03 30 69 .. 26 65 .. 24 70 .. 0.85 2 ? 5.2 0.2 0.029 22 37 72 .. 73 108 .. 56 110 .. 0.90 3 ? 3.9 0.0 0.074 56 38 72 .. 114 148 .. 112 150 .. 0.90 4 ? 3.4 0.0 0.1 76 38 70 .. 154 186 .. 152 190 .. 0.87 5 ? 3.9 0.0 0.074 55 38 73 .. 194 229 .. 191 230 .. 0.90 6 ? 2.4 0.1 0.2 1.5e+02 38 64 .. 234 260 .. 232 270 .. 0.87 7 ? 4.4 0.3 0.05 37 20 70 .. 256 306 .. 249 310 .. 0.80 8 ? 2.5 0.0 0.2 1.5e+02 38 73 .. 314 349 .. 311 351 .. 0.91 9 ? 1.9 0.0 0.3 2.3e+02 38 64 .. 354 380 .. 350 389 .. 0.87 10 ? 2.7 0.1 0.17 1.3e+02 38 71 .. 394 427 .. 391 430 .. 0.86 11 ? 3.7 0.1 0.08 60 38 64 .. 434 460 .. 432 470 .. 0.87 12 ? 4.7 0.1 0.04 30 38 64 .. 474 500 .. 472 509 .. 0.88 13 ! 7.9 0.4 0.0043 3.2 27 71 .. 503 547 .. 489 550 .. 0.76 14 ? 1.4 0.0 0.41 3.1e+02 38 62 .. 554 578 .. 551 589 .. 0.87 15 ? -1.0 0.0 2.3 1.7e+03 39 64 .. 595 620 .. 580 630 .. 0.84 16 ? 3.2 0.1 0.12 87 37 70 .. 633 666 .. 607 670 .. 0.79 17 ? 1.4 0.0 0.42 3.1e+02 38 72 .. 674 708 .. 671 710 .. 0.90 18 ? 3.1 0.0 0.13 95 37 64 .. 713 740 .. 711 750 .. 0.87 19 ? 6.2 0.1 0.014 10 37 72 .. 753 788 .. 736 790 .. 0.85 20 ! 6.9 0.0 0.0085 6.4 38 73 .. 794 829 .. 792 830 .. 0.91 21 ? 2.5 0.0 0.2 1.5e+02 38 70 .. 834 866 .. 832 920 .. 0.85 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 6.2 RPN7 30 lgkeeirraledlaehyakigdlenAlkayerarekttsl 69 l ++ei++a+ + +++ g +++A+++ e+ ++ t+ FUN_002337-T1 26 LCESEIANAYGYTSIAFHSQGYFRKAIEYHEKHLKITMEV 65 67899999999999999************99988777665 PP == domain 2 score: 5.2 bits; conditional E-value: 0.029 RPN7 37 raledlaehyakigdlenAlkayerarekttslghk 72 +++++la+ + + gd+++A+k+ e+ ++ ++ +gh FUN_002337-T1 73 KGYQNLAHAFQSLGDFRKAIKYHEKHLKIAIEAGHR 108 6899*********************99999999987 PP == domain 3 score: 3.9 bits; conditional E-value: 0.074 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + gd+++A+++ e+ ++ ++ gh FUN_002337-T1 114 AYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEVGHR 148 7889********************99998888886 PP == domain 4 score: 3.4 bits; conditional E-value: 0.1 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ +l++ y + gd+++A+++ e+ +e ++ g FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEYHEKHLEIAIEVG 186 7899*******************9998777666 PP == domain 5 score: 3.9 bits; conditional E-value: 0.074 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ l++ y + gd+++A+++ e+ +e ++ gh + FUN_002337-T1 194 ARGSLGNAYRSLGDFRKAIEYHEKHLEIAVEVGHRV 229 56679999*******************999999975 PP == domain 6 score: 2.4 bits; conditional E-value: 0.2 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002337-T1 234 AYGNLGNAYQSLGDFRKAIEYHEKHLE 260 6889******************99877 PP == domain 7 score: 4.4 bits; conditional E-value: 0.05 RPN7 20 eaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslg 70 e++l+ ake + +a+ +l++ y + gd+++A+++ ++ +e ++ g FUN_002337-T1 256 EKHLEIAKEASDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVG 306 56666677777777777899********************99988776665 PP == domain 8 score: 2.5 bits; conditional E-value: 0.2 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l+ y + gd+++A+++ e+ +e ++ gh i FUN_002337-T1 314 AYGNLGIAYDSLGDFRKAIEYHEKHLEIAIEVGHRI 349 6778999999*****************999999987 PP == domain 9 score: 1.9 bits; conditional E-value: 0.3 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002337-T1 354 AYASLGNAYQSLGDFRKAIEYHEKHLE 380 78899*****************99877 PP == domain 10 score: 2.7 bits; conditional E-value: 0.17 RPN7 38 aledlaehyakigdlenAlkayerarekttslgh 71 a+ +l+ y++ gd+++A+++ e+ +e + +h FUN_002337-T1 394 AYGNLGIAYHSLGDFRKAIEYHEKHLEIAKEVSH 427 67789999****************9987777766 PP == domain 11 score: 3.7 bits; conditional E-value: 0.08 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y++ gd+++A+++ e+ +e FUN_002337-T1 434 AYGNLGNAYESLGDFRKAIEYHEKHLE 460 6889******************99877 PP == domain 12 score: 4.7 bits; conditional E-value: 0.04 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y++ gd+++A+++ e+ +e FUN_002337-T1 474 AYGNLGNAYESLGDFQKAIEYHEKHLE 500 6889*****************999876 PP == domain 13 score: 7.9 bits; conditional E-value: 0.0043 RPN7 27 kenlgkeeirraledlaehyakigdlenAlkayerarekttslgh 71 ke + +a+ +l++ y++ gd++nA+++ e+ +e + +h FUN_002337-T1 503 KEVSDRVGEGNAYGNLGNAYESLGDFQNAIEYHEKHLEIAKEVSH 547 55555555567899*********************9987777766 PP == domain 14 score: 1.4 bits; conditional E-value: 0.41 RPN7 38 aledlaehyakigdlenAlkayera 62 a+ +l++ y + gd+++A+++ e+ FUN_002337-T1 554 AYGNLGNTYQSLGDFRKAIEYHEKD 578 6889****************99985 PP == domain 15 score: -1.0 bits; conditional E-value: 2.3 RPN7 39 ledlaehyakigdlenAlkayerare 64 + +l+ y + gd+++A+++ e+ +e FUN_002337-T1 595 YGNLGIAYQSLGDFRKAIEYHEKDLE 620 678888999**********9998666 PP == domain 16 score: 3.2 bits; conditional E-value: 0.12 RPN7 37 raledlaehyakigdlenAlkayerarekttslg 70 +a+ l++ y + gd+++A+++ e+ +e ++ g FUN_002337-T1 633 NAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVG 666 68889*******************9998777666 PP == domain 17 score: 1.4 bits; conditional E-value: 0.42 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ l++ y + gd+++A+ + e+ +e ++ gh FUN_002337-T1 674 AYGSLGNAYQSLGDFRKAIGYHEKHLEIAIEVGHR 708 678899*******************9999999987 PP == domain 18 score: 3.1 bits; conditional E-value: 0.13 RPN7 37 raledlaehyakigdlenAlkayerare 64 +a+ l++ y++ gd+++A+++ e+ +e FUN_002337-T1 713 NAYGSLGNAYESLGDFRKAIEYHEKHLE 740 578899*****************99876 PP == domain 19 score: 6.2 bits; conditional E-value: 0.014 RPN7 37 raledlaehyakigdlenAlkayerarekttslghk 72 +a+ +l++ y + g++++A+k+ e+ +e ++ gh FUN_002337-T1 753 NAYGNLGNAYQSLGEFRKAIKCHEKHLEIAIDVGHR 788 68999**********************999998886 PP == domain 20 score: 6.9 bits; conditional E-value: 0.0085 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ l++ y + gd+++A+++ye+ +e ++ gh + FUN_002337-T1 794 AYGSLGNAYQSLGDVREAIEYYEKHLEIAIEVGHRV 829 677899*********************999999975 PP == domain 21 score: 2.5 bits; conditional E-value: 0.2 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l++ y + gd+++A+++ e+ +e ++ g FUN_002337-T1 834 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVG 866 677899999***********9999888766655 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.4 0.42 3.2e+02 129 180 .. 46 97 .. 26 105 .. 0.76 2 ! 14.2 0.1 4.3e-05 0.033 38 180 .. 115 257 .. 111 268 .. 0.92 3 ! 9.9 0.2 0.00087 0.65 38 180 .. 275 417 .. 262 427 .. 0.87 4 ! 13.0 0.6 9.9e-05 0.075 42 180 .. 439 577 .. 432 588 .. 0.90 5 ! 10.6 0.1 0.00053 0.4 45 180 .. 602 737 .. 594 748 .. 0.78 6 ! 19.9 0.1 7.5e-07 0.00057 40 180 .. 717 857 .. 710 864 .. 0.91 7 ! 14.5 0.0 3.5e-05 0.026 39 142 .. 756 859 .. 745 907 .. 0.79 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.42 SNAP 129 qdlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + ++kAie+ e+ ++ + + a +k ++++A+ +l+++ kAi+ ek FUN_002337-T1 46 GYFRKAIEYHEKHLKITMEVGDRAGEEKGYQNLAHAFQSLGDFRKAIKYHEK 97 5567888888888888888888888888888888888888888888888776 PP == domain 2 score: 14.2 bits; conditional E-value: 4.3e-05 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nayk ++++A e ++k ++ +++ + ++ay + ++y++ d +A+e ek ei +e g+ ++ ++++ y++ +d++ FUN_002337-T1 115 YGNLGNAYKSLGDFRKAIEYHEKHLKIAIEVGHRVGEGSAYRNLGNAYRSLgDFRKAIEYHEKHLEIAIEVGNRVGEGRARGSLGNAYRSL-GDFR 209 556689*******************************************98799***********************************87.**** PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 kAie+ e+ ++ + + +++ ++ + + +l+++ kAie ek FUN_002337-T1 210 KAIEYHEKHLEIAVEVGHRVGEGSAYGNLGNAYQSLGDFRKAIEYHEK 257 ********9999999999999999999999999999999999998886 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00087 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+ ++++A e ++k e+ +++++ +nay + +y + d +A+e ek ei +e g ++ + ++++ y++ +d++ FUN_002337-T1 275 YGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGNRVGEGNAYGNLGIAYDSLgDFRKAIEYHEKHLEIAIEVGHRIGEGNAYASLGNAYQSL-GDFR 369 5566899999999**********************************99877999******************9999***********987.**** PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 kAie+ e+ ++ + + + +++ ++ + +l+++ kAie ek FUN_002337-T1 370 KAIEYHEKHLEIAIEVSDQVGEGSAYGNLGIAYHSLGDFRKAIEYHEK 417 ******999988777777777777777777777778888888877765 PP == domain 4 score: 13.0 bits; conditional E-value: 9.9e-05 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay ++++A e ++k e+ +k++++ ++ay + ++y++ d ++A+e ek ei e ++ + ++++ ye+ +d+++Aie FUN_002337-T1 439 GNAYESLGDFRKAIEYHEKHLEIAKKVSDRVGEGSAYGNLGNAYESLgDFQKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGNAYESL-GDFQNAIE 533 7888899999**********************************997799*************999877777789999*******87.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ ++ ++ + +++ ++ + + +l+++ kAie ek FUN_002337-T1 534 YHEKHLEIAKEVSHRVGEGSAYGNLGNTYQSLGDFRKAIEYHEK 577 ********9999999999999******************99986 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00053 SNAP 45 yklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYe 139 y+ ++++A e ++k e+ ++++++ +nay ++y++ d +A+e ek ei +e g+ ++ + ++++ y++ +d++kAi + e FUN_002337-T1 602 YQSLGDFRKAIEYHEKDLEIAKEVGNRVGEGNAYGSLGNAYQSLgDFRKAIEYHEKHLEIAIEVGNRVGQGNAYGSLGNAYQSL-GDFRKAIGYHE 696 555567788888888888888888888888888888888888866888888888888888888888888888888888888876.88888888888 PP SNAP 140 qAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + ++ + + ++++ + + + +l+++ kAie ek FUN_002337-T1 697 KHLEIAIEVGHRVGEENAYGSLGNAYESLGDFRKAIEYHEK 737 88888888888888888888888888888888888887775 PP == domain 6 score: 19.9 bits; conditional E-value: 7.5e-07 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + +nay ++++A e ++k e+ ++++++ +nay + ++y++ + +A+++ ek ei ++ g ++ + ++++ y++ +d+++A FUN_002337-T1 717 SLGNAYESLGDFRKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGNAYQSLgEFRKAIKCHEKHLEIAIDVGHRVGEGNAYGSLGNAYQSL-GDVREA 811 557899999999**********************************9986999*********************************987.****** PP SNAP 135 ieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 ie+Ye+ ++ + + +++ + + + +l+++ kAie ek FUN_002337-T1 812 IEYYEKHLEIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAIEYHEK 857 ******9999999999999999999999999999999999998876 PP == domain 7 score: 14.5 bits; conditional E-value: 3.5e-05 SNAP 39 kqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlek 133 + +nay+ ++++A ++++k e+ +++ + +nay ++y++ d eA+e +ek ei +e g ++ + ++++ y++ +d++k FUN_002337-T1 756 GNLGNAYQSLGEFRKAIKCHEKHLEIAIDVGHRVGEGNAYGSLGNAYQSLgDVREAIEYYEKHLEIAIEVGHRVGEGNAYGSLGNAYQSL-GDFRK 850 455788888888888888888888888888888888888888888888866888888888888888888888888888888888888876.88888 PP SNAP 134 AieaYeqAa 142 Aie+ e+ FUN_002337-T1 851 AIEYHEKHL 859 888887755 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 3.3 2.5e+03 12 31 .. 40 59 .. 39 62 .. 0.85 2 ? 0.1 0.0 1.7 1.3e+03 13 31 .. 81 99 .. 75 103 .. 0.84 3 ? 1.0 0.0 0.84 6.3e+02 14 31 .. 122 139 .. 119 143 .. 0.89 4 ? 1.2 0.0 0.76 5.7e+02 14 31 .. 162 179 .. 156 182 .. 0.87 5 ? 0.9 0.0 0.96 7.2e+02 14 31 .. 202 219 .. 200 222 .. 0.88 6 ? 1.1 0.0 0.78 5.9e+02 14 31 .. 242 259 .. 239 262 .. 0.89 7 ? -1.9 0.0 7.2 5.4e+03 14 30 .. 282 298 .. 281 301 .. 0.84 8 ? 2.7 0.0 0.26 2e+02 12 31 .. 320 339 .. 316 342 .. 0.88 9 ? 1.2 0.0 0.77 5.8e+02 14 31 .. 362 379 .. 360 383 .. 0.89 10 ? 3.3 0.0 0.17 1.3e+02 12 31 .. 400 419 .. 396 422 .. 0.88 11 ? 0.8 0.0 1 7.7e+02 14 31 .. 442 459 .. 440 462 .. 0.88 12 ? -0.4 0.0 2.4 1.8e+03 14 31 .. 482 499 .. 480 502 .. 0.87 13 ? 1.3 0.0 0.7 5.3e+02 14 31 .. 522 539 .. 519 542 .. 0.88 14 ? 1.0 0.0 0.9 6.7e+02 14 31 .. 562 579 .. 560 582 .. 0.88 15 ? 3.3 0.0 0.17 1.3e+02 12 31 .. 600 619 .. 596 622 .. 0.88 16 ? 1.1 0.0 0.8 6e+02 14 31 .. 642 659 .. 640 662 .. 0.89 17 ? -0.5 0.0 2.5 1.9e+03 14 31 .. 682 699 .. 681 702 .. 0.88 18 ? 0.8 0.0 1 7.7e+02 14 31 .. 722 739 .. 720 742 .. 0.88 19 ? -2.2 0.0 8.5 6.4e+03 14 31 .. 762 779 .. 761 781 .. 0.87 20 ? 1.1 0.0 0.8 6e+02 14 31 .. 842 859 .. 840 862 .. 0.89 21 ? -1.2 0.0 4.3 3.2e+03 13 25 .. 881 893 .. 875 900 .. 0.87 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 3.3 DUF2977 12 isYvlvGgledgidvdednl 31 i + G ++++i+++e+ l FUN_002337-T1 40 IAFHSQGYFRKAIEYHEKHL 59 56777899********9987 PP == domain 2 score: 0.1 bits; conditional E-value: 1.7 DUF2977 13 sYvlvGgledgidvdednl 31 + G ++++i ++e+ l FUN_002337-T1 81 AFQSLGDFRKAIKYHEKHL 99 57789**********9987 PP == domain 3 score: 1.0 bits; conditional E-value: 0.84 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 122 YKSLGDFRKAIEYHEKHL 139 7789***********987 PP == domain 4 score: 1.2 bits; conditional E-value: 0.76 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 162 YRSLGDFRKAIEYHEKHL 179 7889***********987 PP == domain 5 score: 0.9 bits; conditional E-value: 0.96 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 202 YRSLGDFRKAIEYHEKHL 219 7789***********987 PP == domain 6 score: 1.1 bits; conditional E-value: 0.78 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 242 YQSLGDFRKAIEYHEKHL 259 7889***********987 PP == domain 7 score: -1.9 bits; conditional E-value: 7.2 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002337-T1 282 YQSLGDFRKAIEYHAKH 298 7789*********9765 PP == domain 8 score: 2.7 bits; conditional E-value: 0.26 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002337-T1 320 IAYDSLGDFRKAIEYHEKHL 339 88999************987 PP == domain 9 score: 1.2 bits; conditional E-value: 0.77 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 362 YQSLGDFRKAIEYHEKHL 379 7889***********987 PP == domain 10 score: 3.3 bits; conditional E-value: 0.17 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002337-T1 400 IAYHSLGDFRKAIEYHEKHL 419 8999*************987 PP == domain 11 score: 0.8 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 442 YESLGDFRKAIEYHEKHL 459 7789***********987 PP == domain 12 score: -0.4 bits; conditional E-value: 2.4 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 482 YESLGDFQKAIEYHEKHL 499 7789**********9987 PP == domain 13 score: 1.3 bits; conditional E-value: 0.7 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 522 YESLGDFQNAIEYHEKHL 539 7789***********987 PP == domain 14 score: 1.0 bits; conditional E-value: 0.9 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 562 YQSLGDFRKAIEYHEKDL 579 7789**********9877 PP == domain 15 score: 3.3 bits; conditional E-value: 0.17 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002337-T1 600 IAYQSLGDFRKAIEYHEKDL 619 8999************9877 PP == domain 16 score: 1.1 bits; conditional E-value: 0.8 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 642 YQSLGDFRKAIEYHEKHL 659 7889***********987 PP == domain 17 score: -0.5 bits; conditional E-value: 2.5 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i ++e+ l FUN_002337-T1 682 YQSLGDFRKAIGYHEKHL 699 7789**********9987 PP == domain 18 score: 0.8 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 722 YESLGDFRKAIEYHEKHL 739 7789***********987 PP == domain 19 score: -2.2 bits; conditional E-value: 8.5 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i +e+ l FUN_002337-T1 762 YQSLGEFRKAIKCHEKHL 779 7789**********9876 PP == domain 20 score: 1.1 bits; conditional E-value: 0.8 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002337-T1 842 YQSLGDFRKAIEYHEKHL 859 7889***********987 PP == domain 21 score: -1.2 bits; conditional E-value: 4.3 DUF2977 13 sYvlvGgledgid 25 +Y G++e++ d FUN_002337-T1 881 GYFSLGQFENAWD 893 8999******988 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.0 0.042 32 24 70 .. 121 170 .. 95 177 .. 0.82 2 ? 4.4 0.0 0.076 57 25 70 .. 162 210 .. 156 229 .. 0.82 3 ? 1.1 0.0 0.83 6.2e+02 25 69 .. 202 249 .. 176 256 .. 0.80 4 ? 2.7 0.0 0.26 1.9e+02 24 69 .. 241 289 .. 233 298 .. 0.78 5 ? 1.7 0.0 0.55 4.1e+02 28 70 .. 325 370 .. 315 382 .. 0.79 6 ? -0.3 0.0 2.3 1.7e+03 23 55 .. 360 392 .. 352 399 .. 0.73 7 ? 4.8 0.0 0.058 43 25 70 .. 402 450 .. 376 459 .. 0.86 8 ? 4.1 0.0 0.093 70 25 67 .. 442 487 .. 437 500 .. 0.79 9 ? 0.8 0.0 1 7.7e+02 26 65 .. 483 525 .. 479 541 .. 0.75 10 ? 2.5 0.0 0.3 2.2e+02 26 70 .. 523 570 .. 511 577 .. 0.80 11 ? 2.2 0.0 0.37 2.8e+02 24 55 .. 561 592 .. 556 604 .. 0.81 12 ? 6.8 0.0 0.014 10 26 70 .. 603 650 .. 598 664 .. 0.83 13 ? 2.9 0.0 0.23 1.7e+02 24 70 .. 641 690 .. 638 700 .. 0.83 14 ? 3.0 0.0 0.21 1.6e+02 24 65 .. 721 765 .. 695 781 .. 0.79 15 ? 4.7 0.0 0.062 47 24 70 .. 801 850 .. 793 860 .. 0.81 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.042 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + s + ++A+e +e+ + +v ++ s r+Lgn +++ d r+ FUN_002337-T1 121 AYKSLGDFRKAIEYHEKHLKIAIEVGHRVgegSAYRNLGNAYRSLGDFRK 170 5678899**********************887779*******99888776 PP == domain 2 score: 4.4 bits; conditional E-value: 0.076 WH_Halo_primase 25 fhsarelydAleaYepereweqkvkneisspr...sLgnvLkkardhrs 70 s + ++A+e +e+ e +v n++ + r sLgn +++ d r+ FUN_002337-T1 162 YRSLGDFRKAIEYHEKHLEIAIEVGNRVGEGRargSLGNAYRSLGDFRK 210 5677899*********************775533589999998888776 PP == domain 3 score: 1.1 bits; conditional E-value: 0.83 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhr 69 s + ++A+e +e+ e +v ++ s +Lgn +++ d r FUN_002337-T1 202 YRSLGDFRKAIEYHEKHLEIAVEVGHRVgegSAYGNLGNAYQSLGDFR 249 567789999999999999999999999955444567777777766655 PP == domain 4 score: 2.7 bits; conditional E-value: 0.26 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhr 69 + +s + ++A+e +e+ e +++ +++ + +Lgn +++ d r FUN_002337-T1 241 AYQSLGDFRKAIEYHEKHLEIAKEASDRVGEgnaYGNLGNAYQSLGDFR 289 6788999*************99999999965222567777777766655 PP == domain 5 score: 1.7 bits; conditional E-value: 0.55 WH_Halo_primase 28 arelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + ++A+e +e+ e +v +i sLgn +++ d r+ FUN_002337-T1 325 LGDFRKAIEYHEKHLEIAIEVGHRIgegNAYASLGNAYQSLGDFRK 370 5688999999999999999999999544447899999998877766 PP == domain 6 score: -0.3 bits; conditional E-value: 2.3 WH_Halo_primase 23 gefhsarelydAleaYepereweqkvkneissp 55 ++ +s + ++A+e +e+ e +v +++ + FUN_002337-T1 360 NAYQSLGDFRKAIEYHEKHLEIAIEVSDQVGEG 392 456889999*****9999887777777776655 PP == domain 7 score: 4.8 bits; conditional E-value: 0.058 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 hs + ++A+e +e+ e ++v ++ s +Lgn +++ d r+ FUN_002337-T1 402 YHSLGDFRKAIEYHEKHLEIAKEVSHRVgegSAYGNLGNAYESLGDFRK 450 69999***********************665556788888888777665 PP == domain 8 score: 4.1 bits; conditional E-value: 0.093 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkard 67 s + ++A+e +e+ e +kv +++ s +Lgn +++ d FUN_002337-T1 442 YESLGDFRKAIEYHEKHLEIAKKVSDRVgegSAYGNLGNAYESLGD 487 5677899*********************554456677887777655 PP == domain 9 score: 0.8 bits; conditional E-value: 1 WH_Halo_primase 26 hsarelydAleaYepereweqkvkneiss...prsLgnvLkka 65 s + +A+e +e+ e ++v +++ + +Lgn +++ FUN_002337-T1 483 ESLGDFQKAIEYHEKHLEIAKEVSDRVGEgnaYGNLGNAYESL 525 56678899**********99****9996622245666666654 PP == domain 10 score: 2.5 bits; conditional E-value: 0.3 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 s + +A+e +e+ e ++v ++ s +Lgn++++ d r+ FUN_002337-T1 523 ESLGDFQNAIEYHEKHLEIAKEVSHRVgegSAYGNLGNTYQSLGDFRK 570 56778999*******************665556788888888777665 PP == domain 11 score: 2.2 bits; conditional E-value: 0.37 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneissp 55 + +s + ++A+e +e++ e ++v +++ + FUN_002337-T1 561 TYQSLGDFRKAIEYHEKDLEIAKEVSDRVGEG 592 568899*************9999999998765 PP == domain 12 score: 6.8 bits; conditional E-value: 0.014 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 +s + ++A+e +e++ e ++v n++ sLgn +++ d r+ FUN_002337-T1 603 QSLGDFRKAIEYHEKDLEIAKEVGNRVgegNAYGSLGNAYQSLGDFRK 650 678899*********************544447899999999888776 PP == domain 13 score: 2.9 bits; conditional E-value: 0.23 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + +s + ++A+e +e+ e +v n++ sLgn +++ d r+ FUN_002337-T1 641 AYQSLGDFRKAIEYHEKHLEIAIEVGNRVgqgNAYGSLGNAYQSLGDFRK 690 5788899**********************544447799999998877665 PP == domain 14 score: 3.0 bits; conditional E-value: 0.21 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkka 65 + s + ++A+e +e+ e ++v +++ + +Lgn +++ FUN_002337-T1 721 AYESLGDFRKAIEYHEKHLEIAKEVSDRVGEgnaYGNLGNAYQSL 765 45678899*********************6622245666666655 PP == domain 15 score: 4.7 bits; conditional E-value: 0.062 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + +s ++++A+e Ye+ e +v ++ sLgn +++ d r+ FUN_002337-T1 801 AYQSLGDVREAIEYYEKHLEIAIEVGHRVgegNAYGSLGNAYQSLGDFRK 850 678999************99999999999443446799999998877776 PP >> DBD_Tnp_Mut MuDR family transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.63 4.7e+02 9 23 .. 81 95 .. 77 103 .. 0.87 2 ? 2.2 0.0 0.26 1.9e+02 6 23 .. 118 135 .. 114 144 .. 0.88 3 ? 0.1 0.0 1.2 9.1e+02 6 22 .. 158 174 .. 155 179 .. 0.88 4 ? 0.1 0.0 1.3 9.4e+02 6 22 .. 198 214 .. 195 220 .. 0.88 5 ? 0.9 0.0 0.68 5.1e+02 6 23 .. 238 255 .. 236 269 .. 0.85 6 ? 2.3 0.0 0.25 1.9e+02 6 24 .. 278 296 .. 274 304 .. 0.89 7 ? 1.8 0.0 0.36 2.7e+02 6 22 .. 318 334 .. 314 341 .. 0.89 8 ? 1.4 0.0 0.49 3.6e+02 5 23 .. 357 375 .. 353 387 .. 0.86 9 ? 0.7 0.0 0.78 5.8e+02 6 23 .. 398 415 .. 396 430 .. 0.85 10 ? 1.0 0.0 0.64 4.8e+02 6 23 .. 438 455 .. 436 469 .. 0.84 11 ? -2.3 0.0 7 5.2e+03 6 22 .. 478 494 .. 477 499 .. 0.87 12 ? 0.8 0.0 0.73 5.5e+02 6 23 .. 558 575 .. 556 581 .. 0.89 13 ? 1.0 0.0 0.65 4.9e+02 6 23 .. 598 615 .. 595 622 .. 0.89 14 ? 0.6 0.0 0.85 6.4e+02 6 22 .. 638 654 .. 635 659 .. 0.88 15 ? -0.4 0.0 1.8 1.3e+03 6 21 .. 678 693 .. 675 698 .. 0.88 16 ? 0.8 0.0 0.73 5.5e+02 6 23 .. 718 735 .. 715 748 .. 0.88 17 ? 1.6 0.0 0.42 3.2e+02 6 22 .. 758 774 .. 754 781 .. 0.88 18 ? -1.1 0.0 2.9 2.2e+03 6 23 .. 798 815 .. 796 818 .. 0.88 19 ? 0.6 0.0 0.85 6.4e+02 6 22 .. 838 854 .. 835 859 .. 0.88 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.63 DBD_Tnp_Mut 9 kFkdleefrkAlrky 23 F++l +frkA++ + FUN_002337-T1 81 AFQSLGDFRKAIKYH 95 69*********9865 PP == domain 2 score: 2.2 bits; conditional E-value: 0.26 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +k+l +frkA++ + FUN_002337-T1 118 LGNAYKSLGDFRKAIEYH 135 7999**********9865 PP == domain 3 score: 0.1 bits; conditional E-value: 1.2 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002337-T1 158 LGNAYRSLGDFRKAIEY 174 79999*********986 PP == domain 4 score: 0.1 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002337-T1 198 LGNAYRSLGDFRKAIEY 214 68999*********986 PP == domain 5 score: 0.9 bits; conditional E-value: 0.68 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002337-T1 238 LGNAYQSLGDFRKAIEYH 255 69999*********9865 PP == domain 6 score: 2.3 bits; conditional E-value: 0.25 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002337-T1 278 LGNAYQSLGDFRKAIEYHA 296 79999**********9887 PP == domain 7 score: 1.8 bits; conditional E-value: 0.36 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002337-T1 318 LGIAYDSLGDFRKAIEY 334 7999**********986 PP == domain 8 score: 1.4 bits; conditional E-value: 0.49 DBD_Tnp_Mut 5 rvGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002337-T1 357 SLGNAYQSLGDFRKAIEYH 375 58999**********9865 PP == domain 9 score: 0.7 bits; conditional E-value: 0.78 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G + +l +frkA++ + FUN_002337-T1 398 LGIAYHSLGDFRKAIEYH 415 69999*********9865 PP == domain 10 score: 1.0 bits; conditional E-value: 0.64 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002337-T1 438 LGNAYESLGDFRKAIEYH 455 69999*********9865 PP == domain 11 score: -2.3 bits; conditional E-value: 7 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +f+kA++ FUN_002337-T1 478 LGNAYESLGDFQKAIEY 494 68999*********975 PP == domain 12 score: 0.8 bits; conditional E-value: 0.73 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002337-T1 558 LGNTYQSLGDFRKAIEYH 575 6999**********9865 PP == domain 13 score: 1.0 bits; conditional E-value: 0.65 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002337-T1 598 LGIAYQSLGDFRKAIEYH 615 7999**********9865 PP == domain 14 score: 0.6 bits; conditional E-value: 0.85 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002337-T1 638 LGNAYQSLGDFRKAIEY 654 69999*********986 PP == domain 15 score: -0.4 bits; conditional E-value: 1.8 DBD_Tnp_Mut 6 vGlkFkdleefrkAlr 21 +G +++l +frkA+ FUN_002337-T1 678 LGNAYQSLGDFRKAIG 693 69999*********95 PP == domain 16 score: 0.8 bits; conditional E-value: 0.73 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002337-T1 718 LGNAYESLGDFRKAIEYH 735 69999*********9865 PP == domain 17 score: 1.6 bits; conditional E-value: 0.42 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l efrkA++ FUN_002337-T1 758 LGNAYQSLGEFRKAIKC 774 79999*********975 PP == domain 18 score: -1.1 bits; conditional E-value: 2.9 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l ++r+A++ y FUN_002337-T1 798 LGNAYQSLGDVREAIEYY 815 69999*********9865 PP == domain 19 score: 0.6 bits; conditional E-value: 0.85 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002337-T1 838 LGNAYQSLGDFRKAIEY 854 69999*********986 PP >> DUF7542 Family of unknown function (DUF7542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 0.28 2.1e+02 16 35 .. 79 98 .. 75 110 .. 0.83 2 ? 2.3 0.0 0.25 1.9e+02 17 35 .. 120 138 .. 115 150 .. 0.85 3 ? 1.7 0.0 0.4 3e+02 17 35 .. 160 178 .. 154 186 .. 0.86 4 ? 2.3 0.0 0.25 1.9e+02 16 36 .. 199 219 .. 192 230 .. 0.83 5 ? 2.4 0.0 0.23 1.8e+02 17 35 .. 240 258 .. 233 269 .. 0.87 6 ? 0.1 0.0 1.2 9.3e+02 17 35 .. 280 298 .. 274 304 .. 0.85 7 ? 2.8 0.0 0.18 1.4e+02 18 35 .. 321 338 .. 316 350 .. 0.85 8 ? 2.7 0.0 0.19 1.4e+02 16 35 .. 359 378 .. 353 389 .. 0.86 9 ? 1.3 0.1 0.52 3.9e+02 18 35 .. 401 418 .. 396 433 .. 0.84 10 ? 2.7 0.0 0.2 1.5e+02 17 35 .. 440 458 .. 433 471 .. 0.87 11 ? -0.8 0.0 2.4 1.8e+03 17 35 .. 480 498 .. 473 506 .. 0.85 12 ? -0.7 0.0 2.2 1.7e+03 17 35 .. 520 538 .. 515 556 .. 0.82 13 ? 4.2 0.0 0.067 50 16 36 .. 559 579 .. 553 591 .. 0.88 14 ? 2.3 0.0 0.25 1.9e+02 18 36 .. 601 619 .. 595 626 .. 0.89 15 ? 2.5 0.0 0.22 1.7e+02 17 35 .. 640 658 .. 634 666 .. 0.86 16 ? 0.5 0.0 0.94 7.1e+02 17 35 .. 680 698 .. 672 709 .. 0.81 17 ? 2.8 0.0 0.17 1.3e+02 16 35 .. 719 738 .. 706 746 .. 0.86 18 ? 0.9 0.0 0.71 5.3e+02 17 36 .. 760 779 .. 754 789 .. 0.84 19 ? -0.3 0.0 1.7 1.3e+03 17 35 .. 800 818 .. 795 829 .. 0.82 20 ? 2.5 0.0 0.22 1.7e+02 17 35 .. 840 858 .. 834 866 .. 0.86 21 ? -2.8 0.0 10 7.5e+03 14 45 .. 887 918 .. 886 919 .. 0.90 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.28 DUF7542 16 eetfdslraARealddHese 35 ++f+sl++ R+a++ He++ FUN_002337-T1 79 AHAFQSLGDFRKAIKYHEKH 98 679**************975 PP == domain 2 score: 2.3 bits; conditional E-value: 0.25 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 120 NAYKSLGDFRKAIEYHEKH 138 689**************85 PP == domain 3 score: 1.7 bits; conditional E-value: 0.4 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002337-T1 160 NAYRSLGDFRKAIEYHEKH 178 6899*************86 PP == domain 4 score: 2.3 bits; conditional E-value: 0.25 DUF7542 16 eetfdslraARealddHeset 36 +++ sl++ R+a++ He++ FUN_002337-T1 199 GNAYRSLGDFRKAIEYHEKHL 219 5789**************865 PP == domain 5 score: 2.4 bits; conditional E-value: 0.23 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 240 NAYQSLGDFRKAIEYHEKH 258 789*************986 PP == domain 6 score: 0.1 bits; conditional E-value: 1.2 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ H ++ FUN_002337-T1 280 NAYQSLGDFRKAIEYHAKH 298 689*************865 PP == domain 7 score: 2.8 bits; conditional E-value: 0.18 DUF7542 18 tfdslraARealddHese 35 ++dsl++ R+a++ He++ FUN_002337-T1 321 AYDSLGDFRKAIEYHEKH 338 79**************86 PP == domain 8 score: 2.7 bits; conditional E-value: 0.19 DUF7542 16 eetfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 359 GNAYQSLGDFRKAIEYHEKH 378 5789**************86 PP == domain 9 score: 1.3 bits; conditional E-value: 0.52 DUF7542 18 tfdslraARealddHese 35 +++sl++ R+a++ He++ FUN_002337-T1 401 AYHSLGDFRKAIEYHEKH 418 799*************85 PP == domain 10 score: 2.7 bits; conditional E-value: 0.2 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 440 NAYESLGDFRKAIEYHEKH 458 789*************976 PP == domain 11 score: -0.8 bits; conditional E-value: 2.4 DUF7542 17 etfdslraARealddHese 35 ++++sl++ +a++ He++ FUN_002337-T1 480 NAYESLGDFQKAIEYHEKH 498 68999***********975 PP == domain 12 score: -0.7 bits; conditional E-value: 2.2 DUF7542 17 etfdslraARealddHese 35 ++++sl++ +a++ He++ FUN_002337-T1 520 NAYESLGDFQNAIEYHEKH 538 6899************975 PP == domain 13 score: 4.2 bits; conditional E-value: 0.067 DUF7542 16 eetfdslraARealddHeset 36 +t++sl++ R+a++ He++ FUN_002337-T1 559 GNTYQSLGDFRKAIEYHEKDL 579 579***************985 PP == domain 14 score: 2.3 bits; conditional E-value: 0.25 DUF7542 18 tfdslraARealddHeset 36 +++sl++ R+a++ He++ FUN_002337-T1 601 AYQSLGDFRKAIEYHEKDL 619 799*************985 PP == domain 15 score: 2.5 bits; conditional E-value: 0.22 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 640 NAYQSLGDFRKAIEYHEKH 658 789**************86 PP == domain 16 score: 0.5 bits; conditional E-value: 0.94 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a+ He++ FUN_002337-T1 680 NAYQSLGDFRKAIGYHEKH 698 6899999999999999975 PP == domain 17 score: 2.8 bits; conditional E-value: 0.17 DUF7542 16 eetfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 719 GNAYESLGDFRKAIEYHEKH 738 5789*************976 PP == domain 18 score: 0.9 bits; conditional E-value: 0.71 DUF7542 17 etfdslraARealddHeset 36 ++++sl++ R+a++ He++ FUN_002337-T1 760 NAYQSLGEFRKAIKCHEKHL 779 689*************9865 PP == domain 19 score: -0.3 bits; conditional E-value: 1.7 DUF7542 17 etfdslraARealddHese 35 ++++sl++ Rea++ e++ FUN_002337-T1 800 NAYQSLGDVREAIEYYEKH 818 689**********998865 PP == domain 20 score: 2.5 bits; conditional E-value: 0.22 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002337-T1 840 NAYQSLGDFRKAIEYHEKH 858 789**************86 PP == domain 21 score: -2.8 bits; conditional E-value: 10 DUF7542 14 efeetfdslraARealddHesetgHevdWeie 45 +fe+++d++ +A ++ ++ +s e dW+i+ FUN_002337-T1 887 QFENAWDKFVSAVKVFNTLRSFLKSEDDWKIN 918 6899999999999999999999999999*996 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.0 0.0 0.85 6.4e+02 3 20 .. 154 171 .. 152 173 .. 0.89 2 ? 2.0 0.0 0.83 6.2e+02 2 20 .. 193 211 .. 192 213 .. 0.91 3 ? 2.1 0.0 0.78 5.8e+02 3 20 .. 234 251 .. 232 253 .. 0.89 4 ? 1.6 0.0 1.1 8.4e+02 3 20 .. 274 291 .. 272 293 .. 0.89 5 ? -0.2 0.0 4.2 3.2e+03 3 20 .. 314 331 .. 313 332 .. 0.89 6 ? 0.6 0.0 2.5 1.8e+03 3 20 .. 354 371 .. 352 372 .. 0.89 7 ? 4.3 0.0 0.15 1.2e+02 3 20 .. 394 411 .. 392 413 .. 0.89 8 ? -0.2 0.0 4.5 3.4e+03 3 20 .. 434 451 .. 432 452 .. 0.88 9 ? -0.4 0.0 5 3.8e+03 3 20 .. 474 491 .. 472 492 .. 0.88 10 ? -0.1 0.0 3.9 3e+03 3 20 .. 554 571 .. 552 572 .. 0.88 11 ? 2.4 0.0 0.64 4.8e+02 3 20 .. 594 611 .. 592 613 .. 0.89 12 ? -0.6 0.0 5.8 4.3e+03 4 20 .. 635 651 .. 633 652 .. 0.86 13 ? -0.7 0.0 6.3 4.7e+03 4 20 .. 675 691 .. 673 691 .. 0.85 14 ? -0.5 0.0 5.4 4.1e+03 3 20 .. 754 771 .. 753 771 .. 0.87 15 ? 0.5 0.0 2.6 1.9e+03 4 20 .. 795 811 .. 793 813 .. 0.88 16 ? -0.6 0.0 5.8 4.3e+03 4 20 .. 835 851 .. 833 852 .. 0.86 Alignments for each domain: == domain 1 score: 2.0 bits; conditional E-value: 0.85 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002337-T1 154 AYRNLGNAYRSLGDFRKA 171 889***********9887 PP == domain 2 score: 2.0 bits; conditional E-value: 0.83 TPR_4 2 rallaLArallalGdldeA 20 ra+ L+ a+ lGd+ A FUN_002337-T1 193 RARGSLGNAYRSLGDFRKA 211 899************9887 PP == domain 3 score: 2.1 bits; conditional E-value: 0.78 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002337-T1 234 AYGNLGNAYQSLGDFRKA 251 789***********9887 PP == domain 4 score: 1.6 bits; conditional E-value: 1.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002337-T1 274 AYGNLGNAYQSLGDFRKA 291 6789**********9887 PP == domain 5 score: -0.2 bits; conditional E-value: 4.2 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002337-T1 314 AYGNLGIAYDSLGDFRKA 331 6789**********9877 PP == domain 6 score: 0.6 bits; conditional E-value: 2.5 TPR_4 3 allaLArallalGdldeA 20 a++ L+ a++ lGd+ A FUN_002337-T1 354 AYASLGNAYQSLGDFRKA 371 6789**********9877 PP == domain 7 score: 4.3 bits; conditional E-value: 0.15 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002337-T1 394 AYGNLGIAYHSLGDFRKA 411 789***********9887 PP == domain 8 score: -0.2 bits; conditional E-value: 4.5 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002337-T1 434 AYGNLGNAYESLGDFRKA 451 7889**********9877 PP == domain 9 score: -0.4 bits; conditional E-value: 5 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002337-T1 474 AYGNLGNAYESLGDFQKA 491 7889**********9877 PP == domain 10 score: -0.1 bits; conditional E-value: 3.9 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ +++ lGd+ A FUN_002337-T1 554 AYGNLGNTYQSLGDFRKA 571 7889**********9877 PP == domain 11 score: 2.4 bits; conditional E-value: 0.64 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002337-T1 594 AYGNLGIAYQSLGDFRKA 611 7889**********9887 PP == domain 12 score: -0.6 bits; conditional E-value: 5.8 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002337-T1 635 YGSLGNAYQSLGDFRKA 651 5679*********9877 PP == domain 13 score: -0.7 bits; conditional E-value: 6.3 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002337-T1 675 YGSLGNAYQSLGDFRKA 691 5679*********9877 PP == domain 14 score: -0.5 bits; conditional E-value: 5.4 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lG++ A FUN_002337-T1 754 AYGNLGNAYQSLGEFRKA 771 6789**********9876 PP == domain 15 score: 0.5 bits; conditional E-value: 2.6 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd eA FUN_002337-T1 795 YGSLGNAYQSLGDVREA 811 5679**********999 PP == domain 16 score: -0.6 bits; conditional E-value: 5.8 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002337-T1 835 YGSLGNAYQSLGDFRKA 851 5679*********9877 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 0.48 3.6e+02 219 244 .. 76 101 .. 63 105 .. 0.88 2 ? 1.9 0.0 0.24 1.8e+02 219 244 .. 116 141 .. 111 144 .. 0.89 3 ? 0.6 0.0 0.6 4.5e+02 220 243 .. 157 180 .. 152 184 .. 0.87 4 ? 1.2 0.0 0.38 2.8e+02 219 243 .. 196 220 .. 191 224 .. 0.89 5 ? 2.9 0.0 0.12 87 219 246 .. 236 263 .. 231 268 .. 0.87 6 ? 0.0 0.0 0.87 6.5e+02 219 243 .. 276 300 .. 272 303 .. 0.87 7 ? -0.8 0.0 1.6 1.2e+03 220 243 .. 317 340 .. 313 343 .. 0.87 8 ? 1.6 0.0 0.28 2.1e+02 219 243 .. 356 380 .. 352 384 .. 0.87 9 ? 1.7 0.0 0.27 2e+02 219 246 .. 396 423 .. 391 426 .. 0.87 10 ? 2.1 0.0 0.2 1.5e+02 219 246 .. 436 463 .. 431 468 .. 0.87 11 ? 2.2 0.0 0.18 1.4e+02 219 246 .. 476 503 .. 471 507 .. 0.88 12 ? 0.3 0.0 0.72 5.4e+02 219 246 .. 516 543 .. 512 546 .. 0.88 13 ? -1.0 0.0 1.7 1.3e+03 224 250 .. 554 580 .. 551 587 .. 0.51 14 ? -0.2 0.0 1 7.8e+02 220 245 .. 597 622 .. 594 625 .. 0.85 15 ? 1.7 0.0 0.26 2e+02 219 243 .. 636 660 .. 631 664 .. 0.88 16 ? -0.4 0.0 1.1 8.6e+02 219 243 .. 676 700 .. 672 704 .. 0.88 17 ? 2.7 0.0 0.13 97 218 246 .. 715 743 .. 707 746 .. 0.88 18 ? 4.2 0.0 0.046 35 219 243 .. 796 820 .. 791 824 .. 0.89 19 ? 1.7 0.0 0.27 2e+02 219 243 .. 836 860 .. 832 864 .. 0.88 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 0.48 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + +A A+ lg+ rkA +y +k+++ FUN_002337-T1 76 QNLAHAFQSLGDFRKAIKYHEKHLKI 101 67999*****************9875 PP == domain 2 score: 1.9 bits; conditional E-value: 0.24 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 116 GNLGNAYKSLGDFRKAIEYHEKHLKI 141 56899*****************9875 PP == domain 3 score: 0.6 bits; conditional E-value: 0.6 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 157 NLGNAYRSLGDFRKAIEYHEKHLE 180 5899***************99876 PP == domain 4 score: 1.2 bits; conditional E-value: 0.38 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 196 GSLGNAYRSLGDFRKAIEYHEKHLE 220 67999****************9976 PP == domain 5 score: 2.9 bits; conditional E-value: 0.12 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002337-T1 236 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 263 67899*****************988766 PP == domain 6 score: 0.0 bits; conditional E-value: 0.87 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002337-T1 276 GNLGNAYQSLGDFRKAIEYHAKHLE 300 56899**************999875 PP == domain 7 score: -0.8 bits; conditional E-value: 1.6 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 317 NLGIAYDSLGDFRKAIEYHEKHLE 340 67889***************9975 PP == domain 8 score: 1.6 bits; conditional E-value: 0.28 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 356 ASLGNAYQSLGDFRKAIEYHEKHLE 380 56889****************9976 PP == domain 9 score: 1.7 bits; conditional E-value: 0.27 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002337-T1 396 GNLGIAYHSLGDFRKAIEYHEKHLEIAK 423 56889*****************998766 PP == domain 10 score: 2.1 bits; conditional E-value: 0.2 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002337-T1 436 GNLGNAYESLGDFRKAIEYHEKHLEIAK 463 67899*****************988765 PP == domain 11 score: 2.2 bits; conditional E-value: 0.18 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ +kA +y +k+++ +k FUN_002337-T1 476 GNLGNAYESLGDFQKAIEYHEKHLEIAK 503 67899*****************988766 PP == domain 12 score: 0.3 bits; conditional E-value: 0.72 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ ++A +y +k+++ +k FUN_002337-T1 516 GNLGNAYESLGDFQNAIEYHEKHLEIAK 543 56899*****************998766 PP == domain 13 score: -1.0 bits; conditional E-value: 1.7 TPR_15 224 AllllgqnrkALpyfrkkaaqnkddpl 250 A+ lg++ + L frk + +++d + FUN_002337-T1 554 AYGNLGNTYQSLGDFRKAIEYHEKDLE 580 555555555555555554444444443 PP == domain 14 score: -0.2 bits; conditional E-value: 1 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqn 245 ++ A+ lg+ rkA +y +k ++ + FUN_002337-T1 597 NLGIAYQSLGDFRKAIEYHEKDLEIA 622 5788***************9987765 PP == domain 15 score: 1.7 bits; conditional E-value: 0.26 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 636 GSLGNAYQSLGDFRKAIEYHEKHLE 660 67899****************9976 PP == domain 16 score: -0.4 bits; conditional E-value: 1.1 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA y +k+++ FUN_002337-T1 676 GSLGNAYQSLGDFRKAIGYHEKHLE 700 67899***************99876 PP == domain 17 score: 2.7 bits; conditional E-value: 0.13 TPR_15 218 weayAaAllllgqnrkALpyfrkkaaqnk 246 ++ ++ A+ lg+ rkA +y +k+++ +k FUN_002337-T1 715 YGSLGNAYESLGDFRKAIEYHEKHLEIAK 743 678999*****************998766 PP == domain 18 score: 4.2 bits; conditional E-value: 0.046 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ r+A +y++k+++ FUN_002337-T1 796 GSLGNAYQSLGDVREAIEYYEKHLE 820 67899*****************976 PP == domain 19 score: 1.7 bits; conditional E-value: 0.27 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002337-T1 836 GSLGNAYQSLGDFRKAIEYHEKHLE 860 67899****************9976 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 3.1 2.3e+03 5 24 .. 77 96 .. 75 97 .. 0.82 2 ? 4.1 0.1 0.13 95 3 24 .. 115 136 .. 114 137 .. 0.88 3 ? 3.7 0.0 0.17 1.3e+02 3 24 .. 155 176 .. 153 177 .. 0.86 4 ? 2.7 0.0 0.34 2.6e+02 6 24 .. 198 216 .. 196 217 .. 0.86 5 ? 3.1 0.0 0.26 2e+02 2 24 .. 234 256 .. 233 257 .. 0.88 6 ? 1.2 0.0 1 7.6e+02 3 23 .. 275 295 .. 274 297 .. 0.86 7 ? 2.5 0.0 0.4 3e+02 3 24 .. 355 376 .. 354 377 .. 0.87 8 ? 0.9 0.0 1.3 9.6e+02 3 24 .. 395 416 .. 393 417 .. 0.81 9 ? 4.3 0.0 0.11 80 2 24 .. 434 456 .. 433 457 .. 0.89 10 ? 4.0 0.0 0.13 99 2 24 .. 474 496 .. 473 497 .. 0.89 11 ? 1.0 0.0 1.2 9.3e+02 3 24 .. 515 536 .. 514 537 .. 0.87 12 ? -0.5 0.0 3.6 2.7e+03 3 24 .. 555 576 .. 553 577 .. 0.76 13 ? 0.1 0.0 2.3 1.8e+03 8 24 .. 600 616 .. 594 617 .. 0.80 14 ? 4.2 0.0 0.11 85 3 24 .. 635 656 .. 634 657 .. 0.91 15 ? 2.6 0.0 0.38 2.9e+02 3 24 .. 675 696 .. 674 697 .. 0.89 16 ? 5.5 0.0 0.045 34 3 24 .. 715 736 .. 714 737 .. 0.91 17 ? 1.1 0.0 1.1 8.2e+02 3 24 .. 755 776 .. 754 777 .. 0.87 18 ? 6.6 0.0 0.02 15 3 25 .. 795 817 .. 794 817 .. 0.93 19 ? 4.2 0.0 0.11 85 3 24 .. 835 856 .. 834 857 .. 0.91 20 ? -1.3 0.0 6.6 5e+03 8 21 .. 880 893 .. 878 900 .. 0.88 21 ? -0.3 0.0 3.2 2.4e+03 2 20 .. 926 944 .. 925 945 .. 0.88 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 3.1 PPR 5 slIsgycknGkleeAlelfk 24 l +++ + G++++A+++++ FUN_002337-T1 77 NLAHAFQSLGDFRKAIKYHE 96 567888899*******9987 PP == domain 2 score: 4.1 bits; conditional E-value: 0.13 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002337-T1 115 YGNLGNAYKSLGDFRKAIEYHE 136 778889*************987 PP == domain 3 score: 3.7 bits; conditional E-value: 0.17 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002337-T1 155 YRNLGNAYRSLGDFRKAIEYHE 176 777889*************987 PP == domain 4 score: 2.7 bits; conditional E-value: 0.34 PPR 6 lIsgycknGkleeAlelfk 24 l ++y + G++++A+e+++ FUN_002337-T1 198 LGNAYRSLGDFRKAIEYHE 216 6699************987 PP == domain 5 score: 3.1 bits; conditional E-value: 0.26 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002337-T1 234 AYGNLGNAYQSLGDFRKAIEYHE 256 6888999*************987 PP == domain 6 score: 1.2 bits; conditional E-value: 1 PPR 3 ynslIsgycknGkleeAlelf 23 y l ++y + G++++A+e++ FUN_002337-T1 275 YGNLGNAYQSLGDFRKAIEYH 295 777889************975 PP == domain 7 score: 2.5 bits; conditional E-value: 0.4 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002337-T1 355 YASLGNAYQSLGDFRKAIEYHE 376 667889*************987 PP == domain 8 score: 0.9 bits; conditional E-value: 1.3 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +y + G++++A+e+++ FUN_002337-T1 395 YGNLGIAYHSLGDFRKAIEYHE 416 6666678999*********987 PP == domain 9 score: 4.3 bits; conditional E-value: 0.11 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002337-T1 434 AYGNLGNAYESLGDFRKAIEYHE 456 688899**************987 PP == domain 10 score: 4.0 bits; conditional E-value: 0.13 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002337-T1 474 AYGNLGNAYESLGDFQKAIEYHE 496 688899**************987 PP == domain 11 score: 1.0 bits; conditional E-value: 1.2 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G+++ A+e+++ FUN_002337-T1 515 YGNLGNAYESLGDFQNAIEYHE 536 778889************9987 PP == domain 12 score: -0.5 bits; conditional E-value: 3.6 PPR 3 ynslIsgycknGkleeAlelfk 24 y l + y + G++++A+e+++ FUN_002337-T1 555 YGNLGNTYQSLGDFRKAIEYHE 576 55555667789*******9987 PP == domain 13 score: 0.1 bits; conditional E-value: 2.3 PPR 8 sgycknGkleeAlelfk 24 +y + G++++A+e+++ FUN_002337-T1 600 IAYQSLGDFRKAIEYHE 616 588899********987 PP == domain 14 score: 4.2 bits; conditional E-value: 0.11 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002337-T1 635 YGSLGNAYQSLGDFRKAIEYHE 656 99999**************987 PP == domain 15 score: 2.6 bits; conditional E-value: 0.38 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+ +++ FUN_002337-T1 675 YGSLGNAYQSLGDFRKAIGYHE 696 99999************99876 PP == domain 16 score: 5.5 bits; conditional E-value: 0.045 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002337-T1 715 YGSLGNAYESLGDFRKAIEYHE 736 99999**************987 PP == domain 17 score: 1.1 bits; conditional E-value: 1.1 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+++++ FUN_002337-T1 755 YGNLGNAYQSLGEFRKAIKCHE 776 777889************9987 PP == domain 18 score: 6.6 bits; conditional E-value: 0.02 PPR 3 ynslIsgycknGkleeAlelfke 25 y sl ++y + G+++eA+e++++ FUN_002337-T1 795 YGSLGNAYQSLGDVREAIEYYEK 817 99999***************986 PP == domain 19 score: 4.2 bits; conditional E-value: 0.11 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002337-T1 835 YGSLGNAYQSLGDFRKAIEYHE 856 99999**************987 PP == domain 20 score: -1.3 bits; conditional E-value: 6.6 PPR 8 sgycknGkleeAle 21 +gy + G++e A + FUN_002337-T1 880 HGYFSLGQFENAWD 893 69********9987 PP == domain 21 score: -0.3 bits; conditional E-value: 3.2 PPR 2 tynslIsgycknGkleeAl 20 +y ++ +++ + Gk++eAl FUN_002337-T1 926 SYCAMWRSLLRIGKIDEAL 944 6888889999********7 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.37 2.8e+02 77 115 .. 57 95 .. 49 111 .. 0.80 2 ? 0.8 0.0 0.49 3.7e+02 100 170 .. 153 221 .. 130 228 .. 0.70 3 ? 3.7 0.1 0.063 47 101 170 .. 234 301 .. 211 311 .. 0.71 4 ? 3.1 0.1 0.1 75 76 170 .. 256 301 .. 235 347 .. 0.58 5 ? 3.4 0.1 0.082 61 100 173 .. 353 424 .. 334 430 .. 0.82 6 ! 7.3 0.1 0.0052 3.9 78 173 .. 458 544 .. 450 551 .. 0.69 7 ? 3.2 0.0 0.091 68 100 172 .. 553 623 .. 534 628 .. 0.64 8 ? 1.7 0.0 0.26 1.9e+02 95 128 .. 635 661 .. 599 716 .. 0.51 9 ? 4.1 0.0 0.05 37 105 169 .. 718 780 .. 678 797 .. 0.63 10 ? 3.6 0.0 0.069 52 77 126 .. 737 779 .. 720 826 .. 0.61 11 ? 5.2 0.0 0.023 17 88 165 .. 828 903 .. 813 912 .. 0.73 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.37 TPR_NPHP3 77 aYlnaikkledavegeltlakvadlyealGrflkdlgll 115 ++l+ + ++ d +++e+ +++a+ +++lG f k + FUN_002337-T1 57 KHLKITMEVGDRAGEEKGYQNLAHAFQSLGDFRKAIKYH 95 567777888888899999999999999999999988654 PP == domain 2 score: 0.8 bits; conditional E-value: 0.49 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 + y lG+ + lg +a++ ++ Lei + + +r+ L + y g f++a +++++ lei FUN_002337-T1 153 SAYRNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGRARGSLGNAYRSLGDFRKAIEYHEKHLEI 221 457777777777777777777777777775444..233344667777777777777777777777777776 PP == domain 3 score: 3.7 bits; conditional E-value: 0.063 TPR_NPHP3 101 lyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 y lG+ + lg +a++ ++ Lei a D ++++ +L + y+ g f++a +++ + lei FUN_002337-T1 234 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEA--SDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEI 301 56677777777777777777777777776665..455556677777777777777777777777777776 PP == domain 4 score: 3.1 bits; conditional E-value: 0.1 TPR_NPHP3 76 kaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 +++l+ +k+ d v++ + ++ + y++lG f k + +++ + lei FUN_002337-T1 256 EKHLEIAKEASDRVGEGNAYGNLGNAYQSLGDFRKAI-------------------------------------------------EYHAKHLEI 301 3445555555555555555555555555555555554.................................................444333333 PP == domain 5 score: 3.4 bits; conditional E-value: 0.082 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 + y +lG+ + lg +a++ ++ Lei + D+ ++++ +L y g f++a +++++ lei ++ FUN_002337-T1 353 NAYASLGNAYQSLGDFRKAIEYHEKHLEIAIEV--SDQVGEGSAYGNLGIAYHSLGDFRKAIEYHEKHLEIAKE 424 578888888899999999999999999987666..567777888999999999999999999999999999865 PP == domain 6 score: 7.3 bits; conditional E-value: 0.0052 TPR_NPHP3 78 YlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 +l+ +kk+ d v++ + ++ + ye+lG f k a++ ++ Lei + D ++++ +L + y+ g f++a +++++ lei ++ FUN_002337-T1 458 HLEIAKKVSDRVGEGSAYGNLGNAYESLGDFQK-------AIEYHEKHLEIAKEV--SDRVGEGNAYGNLGNAYESLGDFQNAIEYHEKHLEIAKE 544 555566666666666666666666666666655.......555666777776666..456666788888999999999999999999998888765 PP == domain 7 score: 3.2 bits; conditional E-value: 0.091 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 + y lG+ + lg +a++ ++ Lei + D + ++ +L y+ g f++a +++++ lei + FUN_002337-T1 553 SAYGNLGNTYQSLGDFRKAIEYHEKDLEIAKEV--SDRVGEGGAYGNLGIAYQSLGDFRKAIEYHEKDLEIAK 623 456666666666666666777777777776666..45555566777777778888888888888888777765 PP == domain 8 score: 1.7 bits; conditional E-value: 0.26 TPR_NPHP3 95 lakvadlyealGrflkdlgllsqalpaLqraLei 128 ++ + y++lG f k a++ ++ Lei FUN_002337-T1 635 YGSLGNAYQSLGDFRK-------AIEYHEKHLEI 661 3333333333333333.......33333333333 PP == domain 9 score: 4.1 bits; conditional E-value: 0.05 TPR_NPHP3 105 lGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqale 169 lG+ + lg +a++ ++ Lei + D ++++ +L + y+ g+f++a + +++ le FUN_002337-T1 718 LGNAYESLGDFRKAIEYHEKHLEIAKEV--SDRVGEGNAYGNLGNAYQSLGEFRKAIKCHEKHLE 780 4444444444444555555555554444..33344444555555555555555555555555554 PP == domain 10 score: 3.6 bits; conditional E-value: 0.069 TPR_NPHP3 77 aYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraL 126 ++l+ +k++ d v++ + ++ + y++lG+f k + + ++ L FUN_002337-T1 737 KHLEIAKEVSDRVGEGNAYGNLGNAYQSLGEFRKAI-------KCHEKHL 779 455666666666666666666666666666666554.......4444444 PP == domain 11 score: 5.2 bits; conditional E-value: 0.023 TPR_NPHP3 88 avegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldP.DhPlvarslhqLagLyaqwgkfstaealyk 165 v++ + ++ + y++lG f k + + + L+ a+e+ + a + h +++ + L + + w+kf +a ++++ FUN_002337-T1 828 RVGEGNAYGSLGNAYQSLGDFRKAIEYHE---KHLEIAIEVGNRAGEGiSHHNIGHGYFSLGQFENAWDKFVSAVKVFN 903 55555566667777888888877776654...46777888877776543799999999999999999999999988886 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 6.4 4.8e+03 34 53 .. 77 96 .. 75 107 .. 0.78 2 ? -1.6 0.0 5.5 4.1e+03 34 52 .. 117 135 .. 114 144 .. 0.77 3 ? 2.1 0.0 0.37 2.7e+02 31 56 .. 154 179 .. 150 184 .. 0.84 4 ? -1.7 0.0 5.8 4.4e+03 35 56 .. 198 219 .. 190 224 .. 0.73 5 ? 4.9 0.0 0.052 39 32 65 .. 235 268 .. 231 269 .. 0.89 6 ? 0.3 0.0 1.3 1e+03 33 51 .. 276 294 .. 273 302 .. 0.83 7 ? 1.3 0.0 0.65 4.9e+02 33 56 .. 316 339 .. 313 344 .. 0.82 8 ? 0.6 0.0 1.1 8.5e+02 36 57 .. 359 380 .. 353 389 .. 0.78 9 ? 5.2 0.0 0.04 30 32 59 .. 395 422 .. 390 429 .. 0.84 10 ? 1.8 0.0 0.47 3.5e+02 32 59 .. 435 462 .. 432 469 .. 0.80 11 ? 3.8 0.0 0.11 84 32 60 .. 475 503 .. 470 509 .. 0.80 12 ? 2.3 0.0 0.33 2.5e+02 33 59 .. 516 542 .. 513 551 .. 0.81 13 ? 0.6 0.0 1.1 8.3e+02 33 53 .. 556 576 .. 551 589 .. 0.71 14 ? 4.0 0.0 0.094 70 32 51 .. 595 614 .. 592 624 .. 0.85 15 ? 0.2 0.0 1.5 1.1e+03 36 56 .. 639 659 .. 634 663 .. 0.80 16 ? -1.7 0.0 5.9 4.4e+03 36 51 .. 679 694 .. 675 702 .. 0.78 17 ? 0.8 0.0 0.94 7.1e+02 36 60 .. 719 743 .. 714 749 .. 0.81 18 ? 0.5 0.0 1.2 8.8e+02 33 57 .. 756 780 .. 753 785 .. 0.82 19 ? 2.8 0.0 0.22 1.7e+02 36 58 .. 799 821 .. 794 826 .. 0.88 20 ? 0.3 0.0 1.4 1.1e+03 36 56 .. 839 859 .. 834 864 .. 0.80 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 6.4 TPR_9 34 drGllyaqlgcleaAladLe 53 + + + + lg++ +A+++ e FUN_002337-T1 77 NLAHAFQSLGDFRKAIKYHE 96 67889999*******98755 PP == domain 2 score: -1.6 bits; conditional E-value: 5.5 TPR_9 34 drGllyaqlgcleaAladL 52 + G +y lg++ +A+++ FUN_002337-T1 117 NLGNAYKSLGDFRKAIEYH 135 5688899999999999875 PP == domain 3 score: 2.1 bits; conditional E-value: 0.37 TPR_9 31 errdrGllyaqlgcleaAladLeayl 56 +r+ G +y lg++ +A+++ e+ l FUN_002337-T1 154 AYRNLGNAYRSLGDFRKAIEYHEKHL 179 6899**************99866655 PP == domain 4 score: -1.7 bits; conditional E-value: 5.8 TPR_9 35 rGllyaqlgcleaAladLeayl 56 G +y lg++ +A+++ e+ l FUN_002337-T1 198 LGNAYRSLGDFRKAIEYHEKHL 219 5677888999999988766555 PP == domain 5 score: 4.9 bits; conditional E-value: 0.052 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalapdapda 65 + + G +y+ lg++ +A+++ e+ l++a +a d+ FUN_002337-T1 235 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEASDR 268 567899*****************99999998886 PP == domain 6 score: 0.3 bits; conditional E-value: 1.3 TPR_9 33 rdrGllyaqlgcleaAlad 51 + G +y+ lg++ +A+++ FUN_002337-T1 276 GNLGNAYQSLGDFRKAIEY 294 567999**********986 PP == domain 7 score: 1.3 bits; conditional E-value: 0.65 TPR_9 33 rdrGllyaqlgcleaAladLeayl 56 + G++y lg++ +A+++ e+ l FUN_002337-T1 316 GNLGIAYDSLGDFRKAIEYHEKHL 339 678**************9866655 PP == domain 8 score: 0.6 bits; conditional E-value: 1.1 TPR_9 36 GllyaqlgcleaAladLeayla 57 G +y+ lg++ +A+++ e+ l+ FUN_002337-T1 359 GNAYQSLGDFRKAIEYHEKHLE 380 7789999999999988666555 PP == domain 9 score: 5.2 bits; conditional E-value: 0.04 TPR_9 32 rrdrGllyaqlgcleaAladLeaylala 59 + + G++y+ lg++ +A+++ e+ l++a FUN_002337-T1 395 YGNLGIAYHSLGDFRKAIEYHEKHLEIA 422 6789**************9988877765 PP == domain 10 score: 1.8 bits; conditional E-value: 0.47 TPR_9 32 rrdrGllyaqlgcleaAladLeaylala 59 + + G +y+ lg++ +A+++ e+ l++a FUN_002337-T1 435 YGNLGNAYESLGDFRKAIEYHEKHLEIA 462 5678999***********9988877766 PP == domain 11 score: 3.8 bits; conditional E-value: 0.11 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalap 60 + + G +y+ lg++++A+++ e+ l++a FUN_002337-T1 475 YGNLGNAYESLGDFQKAIEYHEKHLEIAK 503 5678999***********99888887765 PP == domain 12 score: 2.3 bits; conditional E-value: 0.33 TPR_9 33 rdrGllyaqlgcleaAladLeaylala 59 + G +y+ lg+++ A+++ e+ l++a FUN_002337-T1 516 GNLGNAYESLGDFQNAIEYHEKHLEIA 542 567899***********9988777765 PP == domain 13 score: 0.6 bits; conditional E-value: 1.1 TPR_9 33 rdrGllyaqlgcleaAladLe 53 + G y+ lg++ +A+++ e FUN_002337-T1 556 GNLGNTYQSLGDFRKAIEYHE 576 566778888888888887644 PP == domain 14 score: 4.0 bits; conditional E-value: 0.094 TPR_9 32 rrdrGllyaqlgcleaAlad 51 + + G++y+ lg++ +A+++ FUN_002337-T1 595 YGNLGIAYQSLGDFRKAIEY 614 5679*************986 PP == domain 15 score: 0.2 bits; conditional E-value: 1.5 TPR_9 36 GllyaqlgcleaAladLeayl 56 G +y+ lg++ +A+++ e+ l FUN_002337-T1 639 GNAYQSLGDFRKAIEYHEKHL 659 7799*********99866655 PP == domain 16 score: -1.7 bits; conditional E-value: 5.9 TPR_9 36 GllyaqlgcleaAlad 51 G +y+ lg++ +A+ + FUN_002337-T1 679 GNAYQSLGDFRKAIGY 694 778999****999866 PP == domain 17 score: 0.8 bits; conditional E-value: 0.94 TPR_9 36 GllyaqlgcleaAladLeaylalap 60 G +y+ lg++ +A+++ e+ l++a FUN_002337-T1 719 GNAYESLGDFRKAIEYHEKHLEIAK 743 7799**********99888887765 PP == domain 18 score: 0.5 bits; conditional E-value: 1.2 TPR_9 33 rdrGllyaqlgcleaAladLeayla 57 + G +y+ lg + +A+++ e+ l+ FUN_002337-T1 756 GNLGNAYQSLGEFRKAIKCHEKHLE 780 567999***********99777665 PP == domain 19 score: 2.8 bits; conditional E-value: 0.22 TPR_9 36 GllyaqlgcleaAladLeaylal 58 G +y+ lg++ +A+++ e+ l++ FUN_002337-T1 799 GNAYQSLGDVREAIEYYEKHLEI 821 789**************998876 PP == domain 20 score: 0.3 bits; conditional E-value: 1.4 TPR_9 36 GllyaqlgcleaAladLeayl 56 G +y+ lg++ +A+++ e+ l FUN_002337-T1 839 GNAYQSLGDFRKAIEYHEKHL 859 7799*********99866655 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.1 0.45 3.4e+02 102 141 .. 57 97 .. 25 102 .. 0.62 2 ? 4.0 0.3 0.028 21 117 248 .. 153 295 .. 95 297 .. 0.45 3 ? 4.9 0.4 0.016 12 70 142 .. 258 298 .. 196 417 .. 0.62 4 ! 8.3 1.0 0.0015 1.1 70 250 .. 258 457 .. 252 465 .. 0.71 5 ! 10.6 0.3 0.00028 0.21 85 248 .. 480 655 .. 469 659 .. 0.62 6 ? 5.5 0.1 0.01 7.9 83 248 .. 551 735 .. 536 740 .. 0.52 7 ! 10.6 0.1 0.00029 0.22 82 250 .. 630 817 .. 617 871 .. 0.73 8 ? -3.7 0.0 6.3 4.7e+03 415 448 .. 884 917 .. 873 918 .. 0.78 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 0.45 TPR_IF140-IFT172 102 kaleva.ekkdrihlrktyynyakhleakgdieeaiklyek 141 k l+++ e dr k y n a+ ++ gd+++aik++ek FUN_002337-T1 57 KHLKITmEVGDRAGEEKGYQNLAHAFQSLGDFRKAIKYHEK 97 33333212345555566666666666666666666666665 PP == domain 2 score: 4.0 bits; conditional E-value: 0.028 TPR_IF140-IFT172 117 ktyynyakhleakgdieeaiklyeksethrfevPrlLfddtea..L.esyvkkskdkelkkWwaqylestgele....talkyyeaaedylsl 202 ++y n + + gd+++ai+++ek ev + + +++ L ++y + + ++ + ++le + e+ + y + + y sl FUN_002337-T1 153 SAYRNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGNRVGEGRARgsLgNAYRSLGDFRKAIEYHEKHLEIAVEVGhrvgEGSAYGNLGNAYQSL 245 455556666666666666666666655555555544444433211212344444444444444444444444331110233333444445555 PP TPR_IF140-IFT172 203 vrvlCyledlekaaelanetgdka....acyhlarqyenadeikeaihff 248 e ek e+a+e++d+ a l+ y++ +++++ai+++ FUN_002337-T1 246 GDFRKAIEYHEKHLEIAKEASDRVgegnAYGNLGNAYQSLGDFRKAIEYH 295 55555555555555555555444322213334555555555555555554 PP == domain 3 score: 4.9 bits; conditional E-value: 0.016 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaekkdrihlrktyynyakhleakgdieeaiklyeks 142 +L++ +ea + + + + y l + yq+ gd+++ai+++ k FUN_002337-T1 258 HLEIAKEASDRVGEGNAYGNLGNAYQS--------------------------------LGDFRKAIEYHAKH 298 344444444444444444444444444................................44444444443332 PP == domain 4 score: 8.3 bits; conditional E-value: 0.0015 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaekk........drihlrktyynyakhleakgdieeaiklyeksethrfevPrlLf 154 +L++ +ea + + + + y l + yq+ g + ka+e k+ +r+ ++y n ++ gd+++ai+++ek ev + FUN_002337-T1 258 HLEIAKEASDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHleiaievgNRVGEGNAYGNLGIAYDSLGDFRKAIEYHEKHLEIAIEVGHRIG 350 7899999999999999999999999999999999876544322222223788888999999999***************99999999988777 PP TPR_IF140-IFT172 155 ddt..eaL.esyvkkskdkelkkWwaqyle....stgeletalkyyeaaedylslvr....vlCyledlekaaelanetgdkaacyhlarqye 236 + + ++L ++y + + ++ + ++le ++++ + y + y sl + + ++le a+e+++ g+ +a l+ ye FUN_002337-T1 351 EGNayASLgNAYQSLGDFRKAIEYHEKHLEiaieVSDQVGEGSAYGNLGIAYHSLGDfrkaIEYHEKHLEIAKEVSHRVGEGSAYGNLGNAYE 443 654114562345555555666666666665111055556666666666677777754112133344456777777778888889999****** PP TPR_IF140-IFT172 237 nadeikeaihfftr 250 + +++++ai+++ + FUN_002337-T1 444 SLGDFRKAIEYHEK 457 ********999866 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00028 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aL.esyvkkskdkelk 173 + y+ l ++ +a + +k le+a++ +dr+ ++y n + e+ gd+++ai+++ek ev + + + +L ++y + + ++ FUN_002337-T1 480 NAYESLGDFQKAIEYHEKHLEIAKEvSDRVGEGNAYGNLGNAYESLGDFQNAIEYHEKHLEIAKEVSHRVGEGSAygNLgNTYQSLGDFRKAI 572 5799999999999999******98647*****************************9987777777665555443113312333333344455 PP TPR_IF140-IFT172 174 kWwaqylestgeletal....kyyeaaedylslv..r..vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihff 248 + + le ++e+ y + y sl r + + +dle a+e+ n g+ a l+ y++ +++++ai+++ FUN_002337-T1 573 EYHEKDLEIAKEVSDRVgeggAYGNLGIAYQSLGdfRkaIEYHEKDLEIAKEVGNRVGEGNAYGSLGNAYQSLGDFRKAIEYH 655 55555555555543322111022222223333321121123334455556666666666666666777777777777777765 PP == domain 6 score: 5.5 bits; conditional E-value: 0.01 TPR_IF140-IFT172 83 sckrydllnklyqasgkwdka.......levaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aL.esyv 164 + + y l + yq+ g + ka le+a++ +dr+ +y n ++ gd+++ai+++ek ev + + ++ +L ++y FUN_002337-T1 551 EGSAYGNLGNTYQSLGDFRKAieyhekdLEIAKEvSDRVGEGGAYGNLGIAYQSLGDFRKAIEYHEKDLEIAKEVGNRVGEGNAygSLgNAYQ 643 555555555555555555544111111144554336777777778788888888888888887777776666676655554433113423344 PP TPR_IF140-IFT172 165 kkskdkelkkWwaqylestgelet....alkyyeaaedylslv..r.vlCyle.dlekaaelanetgdkaacyhlarqyenadeikeaihff 248 + + ++ + ++le + e+ + y + + y sl r y e +le a e+ + g++ a l+ ye+ +++++ai+++ FUN_002337-T1 644 SLGDFRKAIEYHEKHLEIAIEVGNrvgqGNAYGSLGNAYQSLGdfRkAIGYHEkHLEIAIEVGHRVGEENAYGSLGNAYESLGDFRKAIEYH 735 44444555555666665555443311103333333444445431121233433145666666666777777777777777777777777776 PP == domain 7 score: 10.6 bits; conditional E-value: 0.00029 TPR_IF140-IFT172 82 ksckrydllnklyqasgkwdkalevaekk........drihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aL.esy 163 + + y l + yq+ g + ka+e ek+ +r+ ++y + ++ gd+++ai ++ek ev + ++++ +L ++y FUN_002337-T1 630 GEGNAYGSLGNAYQSLGDFRKAIEYHEKHleiaievgNRVGQGNAYGSLGNAYQSLGDFRKAIGYHEKHLEIAIEVGHRVGEENAygSLgNAY 722 555556666666666666666655544432222222378888889999999999999999999999999999999988887776522452456 PP TPR_IF140-IFT172 164 vkkskdkelkkWwaqylestgele....talkyyeaaedylsl..vr..vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihff 248 + + ++ + ++le ++e+ + y + + y sl r ++C+ ++le a ++ + g+ a l+ y++ ++++eai+++ FUN_002337-T1 723 ESLGDFRKAIEYHEKHLEIAKEVSdrvgEGNAYGNLGNAYQSLgeFRkaIKCHEKHLEIAIDVGHRVGEGNAYGSLGNAYQSLGDVREAIEYY 815 666666888889999999888876221133444455555666622334478999999999999999999999999999999999999999999 PP TPR_IF140-IFT172 249 tr 250 + FUN_002337-T1 816 EK 817 76 PP == domain 8 score: -3.7 bits; conditional E-value: 6.3 TPR_IF140-IFT172 415 kqenyhlatkkftqaGdkvkamkaLlksGdteki 448 + ++++ a kf a + ++ ++++lks d ki FUN_002337-T1 884 SLGQFENAWDKFVSAVKVFNTLRSFLKSEDDWKI 917 5578888889999999999999999998887665 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.2 0.0 0.71 5.4e+02 30 68 .. 115 153 .. 111 156 .. 0.78 2 ? -1.2 0.0 4 3e+03 37 67 .. 155 186 .. 149 195 .. 0.58 3 ? -1.3 0.0 4.5 3.3e+03 33 63 .. 198 228 .. 190 236 .. 0.61 4 ? -0.4 0.0 2.3 1.8e+03 30 58 .. 235 263 .. 228 294 .. 0.67 5 ? -0.9 0.0 3.3 2.5e+03 30 61 .. 275 306 .. 270 315 .. 0.56 6 ? -0.7 0.0 2.8 2.1e+03 30 69 .. 315 354 .. 311 366 .. 0.80 7 ? 0.7 0.0 1 7.9e+02 30 64 .. 355 389 .. 351 415 .. 0.78 8 ? -1.0 0.0 3.6 2.7e+03 30 67 .. 395 432 .. 392 451 .. 0.76 9 ? 0.2 0.0 1.5 1.1e+03 30 67 .. 435 472 .. 431 480 .. 0.77 10 ? 0.3 0.0 1.3 1e+03 30 66 .. 475 511 .. 473 522 .. 0.80 11 ? -0.3 0.0 2 1.5e+03 30 64 .. 515 549 .. 512 555 .. 0.78 12 ? -1.0 0.0 3.4 2.6e+03 30 59 .. 555 584 .. 551 614 .. 0.70 13 ? -1.0 0.0 3.4 2.6e+03 30 67 .. 595 632 .. 593 635 .. 0.79 14 ? 0.1 0.0 1.6 1.2e+03 30 67 .. 635 672 .. 630 676 .. 0.74 15 ? -2.2 0.0 8 6e+03 30 54 .. 675 699 .. 671 708 .. 0.64 16 ? -0.3 0.0 2.1 1.6e+03 30 63 .. 715 748 .. 713 755 .. 0.78 17 ? 0.7 0.0 1.1 7.9e+02 34 67 .. 752 786 .. 748 794 .. 0.79 18 ? 1.3 0.0 0.69 5.2e+02 30 67 .. 795 832 .. 792 836 .. 0.83 19 ? 0.2 0.0 1.5 1.1e+03 30 67 .. 835 872 .. 807 876 .. 0.79 Alignments for each domain: == domain 1 score: 1.2 bits; conditional E-value: 0.71 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGm 68 y+ +G++ k Lgd +++++ ++ lk + ++ + G FUN_002337-T1 115 YGNLGNAYKSLGDFRKAIEYHEKHLKIAIEVGHRVGEGS 153 677899999999999999999998888777777666665 PP == domain 2 score: -1.2 bits; conditional E-value: 4 CODH_A_N 37 vktLgdleevLnrarsllkeelk.LekaldaG 67 ++Lg++ + L r++++ ++k Le a++ G FUN_002337-T1 155 YRNLGNAYRSLGDFRKAIEYHEKhLEIAIEVG 186 55666666666666666665544455444444 PP == domain 3 score: -1.3 bits; conditional E-value: 4.5 CODH_A_N 33 tGekvktLgdleevLnrarsllkeelkLeka 63 +G++ + Lgd +++++ ++ l+ + ++ FUN_002337-T1 198 LGNAYRSLGDFRKAIEYHEKHLEIAVEVGHR 228 5666666777777776666666655555554 PP == domain 4 score: -0.4 bits; conditional E-value: 2.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeel 58 y+ +G++ + Lgd +++++ ++ l+ + FUN_002337-T1 235 YGNLGNAYQSLGDFRKAIEYHEKHLEIAK 263 55567777777777777776666555443 PP == domain 5 score: -0.9 bits; conditional E-value: 3.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLe 61 y+ +G++ + Lgd +++++ + l+ + + FUN_002337-T1 275 YGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVG 306 44455666666666666655555554444444 PP == domain 6 score: -0.7 bits; conditional E-value: 2.8 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+ +G + Lgd +++++ ++ l+ + ++ + G a FUN_002337-T1 315 YGNLGIAYDSLGDFRKAIEYHEKHLEIAIEVGHRIGEGNA 354 6678889999999999999999998888777777766665 PP == domain 7 score: 0.7 bits; conditional E-value: 1 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekal 64 ya +G++ + Lgd +++++ ++ l+ + + + FUN_002337-T1 355 YASLGNAYQSLGDFRKAIEYHEKHLEIAIEVSDQV 389 78899999999999999999888877665544444 PP == domain 8 score: -1.0 bits; conditional E-value: 3.6 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G + + Lgd +++++ ++ l+ ++ + + G FUN_002337-T1 395 YGNLGIAYHSLGDFRKAIEYHEKHLEIAKEVSHRVGEG 432 67788888999999999998888887766655544444 PP == domain 9 score: 0.2 bits; conditional E-value: 1.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd +++++ ++ l+ +k + + G FUN_002337-T1 435 YGNLGNAYESLGDFRKAIEYHEKHLEIAKKVSDRVGEG 472 67789999999999999999888887777766555555 PP == domain 10 score: 0.3 bits; conditional E-value: 1.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekalda 66 y+ +G++ + Lgd +++++ ++ l+ ++ + + FUN_002337-T1 475 YGNLGNAYESLGDFQKAIEYHEKHLEIAKEVSDRVGE 511 7789999***********9999988877765555544 PP == domain 11 score: -0.3 bits; conditional E-value: 2 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekal 64 y+ +G++ + Lgd +++++ ++ l+ ++ + + FUN_002337-T1 515 YGNLGNAYESLGDFQNAIEYHEKHLEIAKEVSHRV 549 677899999********999999887776666555 PP == domain 12 score: -1.0 bits; conditional E-value: 3.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G+ + Lgd +++++ ++ l+ ++ FUN_002337-T1 555 YGNLGNTYQSLGDFRKAIEYHEKDLEIAKE 584 566777888888888888777776655544 PP == domain 13 score: -1.0 bits; conditional E-value: 3.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G + + Lgd +++++ ++ l+ ++ ++ + G FUN_002337-T1 595 YGNLGIAYQSLGDFRKAIEYHEKDLEIAKEVGNRVGEG 632 67789999999999999999999888877777766666 PP == domain 14 score: 0.1 bits; conditional E-value: 1.6 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd +++++ ++ l+ + ++ + +G FUN_002337-T1 635 YGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNRVGQG 672 67778888888888888888888877776666665555 PP == domain 15 score: -2.2 bits; conditional E-value: 8 CODH_A_N 30 yaltGekvktLgdleevLnrarsll 54 y+ +G++ + Lgd ++++ ++ l FUN_002337-T1 675 YGSLGNAYQSLGDFRKAIGYHEKHL 699 5566777777777777776655554 PP == domain 16 score: -0.3 bits; conditional E-value: 2.1 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLeka 63 y+ +G++ + Lgd +++++ ++ l+ ++ + FUN_002337-T1 715 YGSLGNAYESLGDFRKAIEYHEKHLEIAKEVSDR 748 778999999********99999988776666555 PP == domain 17 score: 0.7 bits; conditional E-value: 1.1 CODH_A_N 34 GekvktLgdleevLnrarsllkeelk.LekaldaG 67 G++ +Lg++ + L + r+++k ++k Le a+d G FUN_002337-T1 752 GNAYGNLGNAYQSLGEFRKAIKCHEKhLEIAIDVG 786 66777899999999999998887776688887777 PP == domain 18 score: 1.3 bits; conditional E-value: 0.69 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd++e+++ +++ l+ + ++ + G FUN_002337-T1 795 YGSLGNAYQSLGDVREAIEYYEKHLEIAIEVGHRVGEG 832 77899999***********9999998887777766666 PP == domain 19 score: 0.2 bits; conditional E-value: 1.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+ +G++ + Lgd +++++ ++ l+ + ++ G FUN_002337-T1 835 YGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNRAGEG 872 66678888888888888888777777666666655555 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.27 2e+02 5 46 .. 86 133 .. 82 140 .. 0.75 2 ? -0.8 0.0 3.7 2.8e+03 28 46 .. 155 173 .. 152 182 .. 0.73 3 ? 2.3 0.0 0.42 3.1e+02 5 46 .. 166 213 .. 162 224 .. 0.74 4 ? 6.3 0.2 0.023 17 5 46 .. 246 293 .. 242 301 .. 0.89 5 ? 0.1 0.0 2 1.5e+03 26 46 .. 313 333 .. 310 344 .. 0.82 6 ? 1.7 0.1 0.63 4.7e+02 5 46 .. 326 373 .. 324 382 .. 0.68 7 ? 2.6 0.1 0.34 2.5e+02 5 46 .. 366 413 .. 352 423 .. 0.72 8 ? 5.4 0.0 0.042 32 4 47 .. 405 454 .. 402 471 .. 0.87 9 ? 5.2 0.0 0.05 37 5 47 .. 446 494 .. 443 509 .. 0.86 10 ? 5.0 0.1 0.058 43 5 46 .. 486 533 .. 482 548 .. 0.89 11 ? 4.8 0.0 0.069 52 5 46 .. 526 573 .. 522 589 .. 0.91 12 ? 2.9 0.1 0.26 1.9e+02 5 46 .. 566 613 .. 562 624 .. 0.84 13 ? 2.1 0.1 0.46 3.5e+02 5 46 .. 606 653 .. 602 662 .. 0.83 14 ? 0.1 0.0 2 1.5e+03 5 45 .. 646 692 .. 642 694 .. 0.68 15 ? 5.9 0.0 0.031 23 5 46 .. 726 773 .. 722 781 .. 0.91 16 ? 1.5 0.0 0.74 5.6e+02 27 50 .. 794 817 .. 790 822 .. 0.75 17 ? 2.6 0.0 0.33 2.5e+02 5 46 .. 806 853 .. 803 861 .. 0.77 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.27 TPR_19 5 gdydeAlalLeqalae..dPd....naearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + + a+ +L++a+ lg++ +A++ FUN_002337-T1 86 GDFRKAIKYHEKHLKIaiEAGhrvgEGNAYGNLGNAYKSLGDFRKAIE 133 778888888888443322333455589999***************987 PP == domain 2 score: -0.8 bits; conditional E-value: 3.7 TPR_19 28 rllLArallalgrldeAea 46 + +L++a+ lg++ +A++ FUN_002337-T1 155 YRNLGNAYRSLGDFRKAIE 173 5677888888888888876 PP == domain 3 score: 2.3 bits; conditional E-value: 0.42 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + +ar L++a+ lg++ +A++ FUN_002337-T1 166 GDFRKAIEYHEKHLEIAIEvgnrvgEGRARGSLGNAYRSLGDFRKAIE 213 788888888888665533333335588999999999999999999987 PP == domain 4 score: 6.3 bits; conditional E-value: 0.023 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002337-T1 246 GDFRKAIEYHEKHLEIAKEasdrvgEGNAYGNLGNAYQSLGDFRKAIE 293 99**********8888777777999999******************87 PP == domain 5 score: 0.1 bits; conditional E-value: 2 TPR_19 26 earllLArallalgrldeAea 46 a+ +L+ a+ lg++ +A++ FUN_002337-T1 313 NAYGNLGIAYDSLGDFRKAIE 333 678889999999999999986 PP == domain 6 score: 1.7 bits; conditional E-value: 0.63 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a++ L++a+ lg++ +A++ FUN_002337-T1 326 GDFRKAIEYHEKHLEIAIEvghrigEGNAYASLGNAYQSLGDFRKAIE 373 667777777777555522222233366777778999999999999987 PP == domain 7 score: 2.6 bits; conditional E-value: 0.34 TPR_19 5 gdydeAlalLeq....alaedPd..naearllLArallalgrldeAea 46 gd+ +A+++ e+ a++ + + a+ +L+ a+ lg++ +A++ FUN_002337-T1 366 GDFRKAIEYHEKhleiAIEVSDQvgEGSAYGNLGIAYHSLGDFRKAIE 413 677777777777444444444445577788888888888888888876 PP == domain 8 score: 5.4 bits; conditional E-value: 0.042 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002337-T1 405 LGDFRKAIEYHEKHLEIAKEvshrvgEGSAYGNLGNAYESLGDFRKAIEY 454 59999999999999999888888999999******************986 PP == domain 9 score: 5.2 bits; conditional E-value: 0.05 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002337-T1 446 GDFRKAIEYHEKHLEIAKKvsdrvgEGSAYGNLGNAYESLGDFQKAIEY 494 8999999999999999888888888999999***************985 PP == domain 10 score: 5.0 bits; conditional E-value: 0.058 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+++A+++ e+ l+++ + a+ +L++a+ lg++ A++ FUN_002337-T1 486 GDFQKAIEYHEKHLEIAKEvsdrvgEGNAYGNLGNAYESLGDFQNAIE 533 9***********9999888888999999**************999987 PP == domain 11 score: 4.8 bits; conditional E-value: 0.069 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd++ A+++ e+ l+++ + a+ +L++++ lg++ +A++ FUN_002337-T1 526 GDFQNAIEYHEKHLEIAKEvshrvgEGSAYGNLGNTYQSLGDFRKAIE 573 9***********9999888888999999******************87 PP == domain 12 score: 2.9 bits; conditional E-value: 0.26 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L+ a+ lg++ +A++ FUN_002337-T1 566 GDFRKAIEYHEKDLEIAKEvsdrvgEGGAYGNLGIAYQSLGDFRKAIE 613 8889999999987777666666788999999**************987 PP == domain 13 score: 2.1 bits; conditional E-value: 0.46 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002337-T1 606 GDFRKAIEYHEKDLEIAKEvgnrvgEGNAYGSLGNAYQSLGDFRKAIE 653 88888888888877777777777888999999999*******999987 PP == domain 14 score: 0.1 bits; conditional E-value: 2 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAe 45 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A+ FUN_002337-T1 646 GDFRKAIEYHEKHLEIAIEvgnrvgQGNAYGSLGNAYQSLGDFRKAI 692 77777777777755552222223447788888899999999998885 PP == domain 15 score: 5.9 bits; conditional E-value: 0.031 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002337-T1 726 GDFRKAIEYHEKHLEIAKEvsdrvgEGNAYGNLGNAYQSLGEFRKAIK 773 9999********99998888889999********************97 PP == domain 16 score: 1.5 bits; conditional E-value: 0.74 TPR_19 27 arllLArallalgrldeAealLaa 50 a+ L++a+ lg++ eA++ ++ FUN_002337-T1 794 AYGSLGNAYQSLGDVREAIEYYEK 817 666788899999999999887766 PP == domain 17 score: 2.6 bits; conditional E-value: 0.33 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd eA++++e+ l+++ + a+ L++a+ lg++ +A++ FUN_002337-T1 806 GDVREAIEYYEKHLEIAIEvghrvgEGNAYGSLGNAYQSLGDFRKAIE 853 888999999999776633333344488999999999999999999986 PP >> Sec1 Sec1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 1.2 9.3e+02 284 332 .. 53 104 .. 48 115 .. 0.75 2 ? -0.7 0.1 1.1 8.3e+02 292 333 .. 99 145 .. 71 179 .. 0.66 3 ? -2.8 0.0 4.8 3.6e+03 303 337 .. 155 189 .. 129 192 .. 0.80 4 ? 2.1 0.0 0.16 1.2e+02 305 339 .. 237 271 .. 199 314 .. 0.73 5 ? 0.3 0.0 0.54 4.1e+02 303 339 .. 355 391 .. 328 402 .. 0.83 6 ? -1.7 0.0 2.1 1.6e+03 311 338 .. 403 430 .. 394 438 .. 0.89 7 ? 2.3 0.0 0.13 1e+02 299 338 .. 427 470 .. 407 474 .. 0.74 8 ? 5.7 0.0 0.013 9.8 283 339 .. 452 511 .. 434 515 .. 0.75 9 ? 1.4 0.0 0.25 1.9e+02 305 339 .. 517 551 .. 511 580 .. 0.85 10 ? -2.3 0.0 3.5 2.6e+03 302 338 .. 634 670 .. 609 680 .. 0.79 11 ? 2.9 0.0 0.089 67 306 339 .. 718 751 .. 707 788 .. 0.74 12 ? -2.3 0.0 3.4 2.6e+03 306 337 .. 798 829 .. 792 861 .. 0.81 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 1.2 Sec1 284 elkaknaelkrk.gaks....sesiadlkdfvekLpelqeekkklslHtnlaee 332 e+ +k+ +++ + g + ++ ++l ++ ++L+++++ k ++H+++a e FUN_002337-T1 53 EYHEKHLKITMEvG--DrageEKGYQNLAHAFQSLGDFRKAIKYHEKHLKIAIE 104 56666644444333..24466788999************************966 PP == domain 2 score: -0.7 bits; conditional E-value: 1.1 Sec1 292 lkrk.gaks....sesiadlkdfvekLpelqeekkklslHtnlaeel 333 lk +a + + +l ++ ++L+++++ + ++H+++a e+ FUN_002337-T1 99 LKIAiEAGHrvgeGNAYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEV 145 33322222245555666777888888888888888888888888766 PP == domain 3 score: -2.8 bits; conditional E-value: 4.8 Sec1 303 iadlkdfvekLpelqeekkklslHtnlaeellkii 337 ++l ++ ++L+++++ + ++H+++a e+ +++ FUN_002337-T1 155 YRNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGNRV 189 567889999******************98876665 PP == domain 4 score: 2.1 bits; conditional E-value: 0.16 Sec1 305 dlkdfvekLpelqeekkklslHtnlaeellkiikk 339 +l ++ ++L+++++ + ++H+++a e ++++ + FUN_002337-T1 237 NLGNAYQSLGDFRKAIEYHEKHLEIAKEASDRVGE 271 56677778888888888888888888887777765 PP == domain 5 score: 0.3 bits; conditional E-value: 0.54 Sec1 303 iadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 a l ++ ++L+++++ + ++H+++a e+++++ + FUN_002337-T1 355 YASLGNAYQSLGDFRKAIEYHEKHLEIAIEVSDQVGE 391 567889999***********************99875 PP == domain 6 score: -1.7 bits; conditional E-value: 2.1 Sec1 311 ekLpelqeekkklslHtnlaeellkiik 338 +L+++++ + ++H+++a e+++++ FUN_002337-T1 403 HSLGDFRKAIEYHEKHLEIAKEVSHRVG 430 5799*******************99886 PP == domain 7 score: 2.3 bits; conditional E-value: 0.13 Sec1 299 s....sesiadlkdfvekLpelqeekkklslHtnlaeellkiik 338 + + +l ++ e+L+++++ + ++H+++a ++++++ FUN_002337-T1 427 HrvgeGSAYGNLGNAYESLGDFRKAIEYHEKHLEIAKKVSDRVG 470 23444567789999*************************99886 PP == domain 8 score: 5.7 bits; conditional E-value: 0.013 Sec1 283 kelkaknaelkrkgaks....sesiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 e+ +k+ e+ +k +++ + +l ++ e+L+++q+ + ++H+++a e+++++ + FUN_002337-T1 452 IEYHEKHLEIAKK-VSDrvgeGSAYGNLGNAYESLGDFQKAIEYHEKHLEIAKEVSDRVGE 511 4555555444443.33345656778899999999999999999999999999999998865 PP == domain 9 score: 1.4 bits; conditional E-value: 0.25 Sec1 305 dlkdfvekLpelqeekkklslHtnlaeellkiikk 339 +l ++ e+L+++q+ + ++H+++a e+++++ + FUN_002337-T1 517 NLGNAYESLGDFQNAIEYHEKHLEIAKEVSHRVGE 551 6778999***********************99876 PP == domain 10 score: -2.3 bits; conditional E-value: 3.5 Sec1 302 siadlkdfvekLpelqeekkklslHtnlaeellkiik 338 l ++ ++L+++++ + ++H+++a e+ +++ FUN_002337-T1 634 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVGNRVG 670 5567888999*******************99877765 PP == domain 11 score: 2.9 bits; conditional E-value: 0.089 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ e+L+++++ + ++H+++a e+++++ + FUN_002337-T1 718 LGNAYESLGDFRKAIEYHEKHLEIAKEVSDRVGE 751 6678899999999999999999999999999977 PP == domain 12 score: -2.3 bits; conditional E-value: 3.4 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkii 337 l ++ ++L++ +e + +++H+++a e+ +++ FUN_002337-T1 798 LGNAYQSLGDVREAIEYYEKHLEIAIEVGHRV 829 567788999999999*******9998876665 PP >> Transferase Transferase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 0.63 4.7e+02 274 325 .. 94 145 .. 83 162 .. 0.87 2 ? 2.8 0.0 0.068 51 272 325 .. 172 225 .. 161 244 .. 0.86 3 ? 1.3 0.0 0.19 1.5e+02 272 322 .. 212 262 .. 201 273 .. 0.83 4 ? 1.6 0.0 0.16 1.2e+02 274 324 .. 334 384 .. 327 397 .. 0.86 5 ? -2.6 0.0 3 2.2e+03 277 324 .. 617 664 .. 609 671 .. 0.82 6 ? 1.8 0.0 0.13 1e+02 276 328 .. 696 747 .. 682 757 .. 0.85 7 ? 3.9 0.0 0.033 25 269 324 .. 769 824 .. 762 831 .. 0.85 8 ? 1.6 0.0 0.16 1.2e+02 276 326 .. 816 866 .. 807 878 .. 0.86 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.63 Transferase 274 eketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivek 325 +e+ l ia++ +r+ + + GNa+ s + +a e ++ l+ ++e FUN_002337-T1 94 YHEKHLKIAIEAGHRVGEGNAYGNLGNAYKSLGDFRKAIEYHEKHLKIAIEV 145 4568999*********************************999999988765 PP == domain 2 score: 2.8 bits; conditional E-value: 0.068 Transferase 272 deeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivek 325 e +e+ l ia+++ +r+ + +++ GNa+ s + +a e ++ l +ve FUN_002337-T1 172 IEYHEKHLEIAIEVGNRVGEGRARGSLGNAYRSLGDFRKAIEYHEKHLEIAVEV 225 45567999********************************99999999988875 PP == domain 3 score: 1.3 bits; conditional E-value: 0.19 Transferase 272 deeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsri 322 e +e+ l iav++ +r+ + + GNa++s + +a e ++ l + FUN_002337-T1 212 IEYHEKHLEIAVEVGHRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIA 262 5556799****************************9999999999888644 PP == domain 4 score: 1.6 bits; conditional E-value: 0.16 Transferase 274 eketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 +e+ l ia+++ +r+ + + GNa++s + +a e ++ l ++e FUN_002337-T1 334 YHEKHLEIAIEVGHRIGEGNAYASLGNAYQSLGDFRKAIEYHEKHLEIAIE 384 456899********************************9999999987765 PP == domain 5 score: -2.6 bits; conditional E-value: 3 Transferase 277 tvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 + l ia ++ +r+ + ++ GNa++s + +a e ++ l ++e FUN_002337-T1 617 KDLEIAKEVGNRVGEGNAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIE 664 66777788888999999999**********999999999999887665 PP == domain 6 score: 1.8 bits; conditional E-value: 0.13 Transferase 276 etvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivekvke 328 e+ l ia+++ +r+ ++ ++ GNa+ s + +a e ++ l i+++v+ FUN_002337-T1 696 EKHLEIAIEVGHRVGEENAYGSLGNAYESLGDFRKAIEYHEKHLE-IAKEVSD 747 58899****************************999999999885.4555555 PP == domain 7 score: 3.9 bits; conditional E-value: 0.033 Transferase 269 skldeeketvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrive 324 +k+ +++e+ l ia+d+ +r+ + ++ GNa++s +a e ++ l ++e FUN_002337-T1 769 RKAIKCHEKHLEIAIDVGHRVGEGNAYGSLGNAYQSLGDVREAIEYYEKHLEIAIE 824 566678899***************************99888888888888776655 PP == domain 8 score: 1.6 bits; conditional E-value: 0.16 Transferase 276 etvlgiavdiRsrlepklpesyfGNallsvvvkstakellseelsrivekv 326 e+ l ia+++ +r+ + ++ GNa++s + +a e ++ l ++e FUN_002337-T1 816 EKHLEIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAIEYHEKHLEIAIEVG 866 47899*********************************9999998877655 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 0.0 7.3 5.5e+03 88 106 .. 113 131 .. 87 136 .. 0.61 2 ? 2.3 0.2 0.37 2.8e+02 75 106 .. 180 211 .. 123 214 .. 0.81 3 ? -1.4 0.0 5.1 3.8e+03 83 106 .. 228 251 .. 216 254 .. 0.62 4 ? 1.4 0.0 0.7 5.2e+02 75 107 .. 260 292 .. 246 294 .. 0.82 5 ? 2.4 0.0 0.33 2.5e+02 75 107 .. 340 372 .. 318 374 .. 0.79 6 ? 2.4 0.0 0.33 2.5e+02 75 107 .. 420 452 .. 403 454 .. 0.84 7 ? 0.5 0.0 1.4 1e+03 75 107 .. 460 492 .. 451 494 .. 0.84 8 ? 2.6 0.0 0.29 2.1e+02 75 106 .. 540 571 .. 489 574 .. 0.78 9 ? -1.7 0.0 6.4 4.8e+03 75 107 .. 580 612 .. 575 614 .. 0.85 10 ? 3.4 0.0 0.17 1.3e+02 75 107 .. 620 652 .. 600 654 .. 0.85 11 ? -0.2 0.0 2.1 1.6e+03 79 106 .. 664 691 .. 655 694 .. 0.75 12 ? 0.1 0.0 1.8 1.3e+03 78 107 .. 703 732 .. 694 734 .. 0.80 13 ? 1.9 0.0 0.49 3.7e+02 75 106 .. 740 771 .. 727 774 .. 0.78 14 ? 0.1 0.0 1.7 1.3e+03 90 115 .. 788 813 .. 777 814 .. 0.72 15 ? 0.6 0.0 1.2 9.4e+02 76 107 .. 821 852 .. 809 854 .. 0.74 16 ? 1.0 0.0 0.89 6.7e+02 51 92 .. 1282 1323 .. 1276 1334 .. 0.73 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 7.3 GGDEF_2 88 tvriGvGrpveglaglrrS 106 +++ +G+++ +l ++r++ FUN_002337-T1 113 NAYGNLGNAYKSLGDFRKA 131 3333345555555555554 PP == domain 2 score: 2.3 bits; conditional E-value: 0.37 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e++ ++ +r+g+ ++r +G+++++l ++r++ FUN_002337-T1 180 EIAIEVGNRVGEGRARGSLGNAYRSLGDFRKA 211 56666777778888888999999999999887 PP == domain 3 score: -1.4 bits; conditional E-value: 5.1 GGDEF_2 83 rlggitvriGvGrpveglaglrrS 106 r+g+ +++ +G+++++l ++r++ FUN_002337-T1 228 RVGEGSAYGNLGNAYQSLGDFRKA 251 444445555567777777777776 PP == domain 4 score: 1.4 bits; conditional E-value: 0.7 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++++ ++r+g+ +++ +G+++++l ++r++ FUN_002337-T1 260 EIAKEASDRVGEGNAYGNLGNAYQSLGDFRKAI 292 788999999999999999999999999999985 PP == domain 5 score: 2.4 bits; conditional E-value: 0.33 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ ++++ +G+++++l ++r++ FUN_002337-T1 340 EIAIEVGHRIGEGNAYASLGNAYQSLGDFRKAI 372 566667777788899999999999999999875 PP == domain 6 score: 2.4 bits; conditional E-value: 0.33 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++e+l ++r++ FUN_002337-T1 420 EIAKEVSHRVGEGSAYGNLGNAYESLGDFRKAI 452 899999999999999999***********9985 PP == domain 7 score: 0.5 bits; conditional E-value: 1.4 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++e+l ++ ++ FUN_002337-T1 460 EIAKKVSDRVGEGSAYGNLGNAYESLGDFQKAI 492 789999999999999999999999999999875 PP == domain 8 score: 2.6 bits; conditional E-value: 0.29 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002337-T1 540 EIAKEVSHRVGEGSAYGNLGNTYQSLGDFRKA 571 78888888888888888888888888888887 PP == domain 9 score: -1.7 bits; conditional E-value: 6.4 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ ++ +G ++++l ++r++ FUN_002337-T1 580 EIAKEVSDRVGEGGAYGNLGIAYQSLGDFRKAI 612 789999999999999999999999****99985 PP == domain 10 score: 3.4 bits; conditional E-value: 0.17 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ +++ +G+++++l ++r++ FUN_002337-T1 620 EIAKEVGNRVGEGNAYGSLGNAYQSLGDFRKAI 652 899999999999******************986 PP == domain 11 score: -0.2 bits; conditional E-value: 2.1 GGDEF_2 79 rlrrrlggitvriGvGrpveglaglrrS 106 ++ +r+g+ +++ +G+++++l ++r++ FUN_002337-T1 664 EVGNRVGQGNAYGSLGNAYQSLGDFRKA 691 5566667778888899999999999986 PP == domain 12 score: 0.1 bits; conditional E-value: 1.8 GGDEF_2 78 erlrrrlggitvriGvGrpveglaglrrSy 107 ++ +r+g+ +++ +G+++e+l ++r++ FUN_002337-T1 703 IEVGHRVGEENAYGSLGNAYESLGDFRKAI 732 556667777888999************986 PP == domain 13 score: 1.9 bits; conditional E-value: 0.49 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002337-T1 740 EIAKEVSDRVGEGNAYGNLGNAYQSLGEFRKA 771 78888888888888888889999999988887 PP == domain 14 score: 0.1 bits; conditional E-value: 1.7 GGDEF_2 90 riGvGrpveglaglrrSyreArrAlr 115 r+G G+++ +l ++++S + r+A++ FUN_002337-T1 788 RVGEGNAYGSLGNAYQSLGDVREAIE 813 67777788888888888777777765 PP == domain 15 score: 0.6 bits; conditional E-value: 1.2 GGDEF_2 76 llerlrrrlggitvriGvGrpveglaglrrSy 107 ++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002337-T1 821 IAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAI 852 55556666777788888999999999999875 PP == domain 16 score: 1.0 bits; conditional E-value: 0.89 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvriG 92 +l+a ++ lv+l++ ddea + e+++r+ ++l++ t++++ FUN_002337-T1 1282 AFLAAGARSVLVALWAIDDEA-TMEFMKRFYQHLKDgKTASAA 1323 56777788899*******985.468888888888885444444 PP >> TPR_COPA_B COPA/B TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 7.5 5.6e+03 59 94 .. 57 92 .. 44 108 .. 0.77 2 ? 0.3 0.0 0.92 6.9e+02 59 97 .. 137 175 .. 120 182 .. 0.84 3 ? -1.6 0.0 3.5 2.6e+03 59 98 .. 217 256 .. 207 294 .. 0.72 4 ? 0.1 0.0 1.1 8e+02 42 98 .. 318 376 .. 311 388 .. 0.81 5 ? -0.6 0.0 1.7 1.3e+03 58 97 .. 416 455 .. 391 466 .. 0.76 6 ? -1.3 0.0 2.8 2.1e+03 59 98 .. 457 496 .. 446 504 .. 0.83 7 ? -0.4 0.0 1.5 1.1e+03 59 98 .. 497 536 .. 476 548 .. 0.80 8 ? -1.1 0.0 2.4 1.8e+03 59 97 .. 537 575 .. 526 585 .. 0.78 9 ? -0.9 0.0 2 1.5e+03 58 98 .. 616 656 .. 596 664 .. 0.81 10 ? -0.6 0.0 1.7 1.3e+03 58 95 .. 696 733 .. 681 740 .. 0.82 11 ? 3.1 0.0 0.13 95 59 100 .. 737 778 .. 726 786 .. 0.88 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 7.5 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklae 94 ++l++++e+ ++a +e+ +++l+ + + g+++ a FUN_002337-T1 57 KHLKITMEVGDRAGEEKGYQNLAHAFQSLGDFRKAI 92 568888888888888888888888888877777665 PP == domain 2 score: 0.3 bits; conditional E-value: 0.92 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecl 97 ++l++a e+ ++ + + +++lg++ + g+++ a e FUN_002337-T1 137 KHLKIAIEVGHRVGEGSAYRNLGNAYRSLGDFRKAIEYH 175 6899*********************99999999888765 PP == domain 3 score: -1.6 bits; conditional E-value: 3.5 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecle 98 ++le+a e+ ++ + + + +lg++ + g+++ a e e FUN_002337-T1 217 KHLEIAVEVGHRVGEGSAYGNLGNAYQSLGDFRKAIEYHE 256 4577777777777777777777777777777766665444 PP == domain 4 score: 0.1 bits; conditional E-value: 1.1 TPR_COPA_B 42 LevstdpehkFdLalql..gklevalelakeadseqkwkqlgdlalkkgklklaeecle 98 L ++ d+ F a++ ++le+a e+ ++ + + + +lg++ + g+++ a e e FUN_002337-T1 318 LGIAYDSLGDFRKAIEYheKHLEIAIEVGHRIGEGNAYASLGNAYQSLGDFRKAIEYHE 376 66777777777777766225799********************9999999998887655 PP == domain 5 score: -0.6 bits; conditional E-value: 1.7 TPR_COPA_B 58 lgklevalelakeadseqkwkqlgdlalkkgklklaeecl 97 ++le+a+e+ ++ + + + +lg++ + g+++ a e FUN_002337-T1 416 EKHLEIAKEVSHRVGEGSAYGNLGNAYESLGDFRKAIEYH 455 3578889999999999999999999888888888777655 PP == domain 6 score: -1.3 bits; conditional E-value: 2.8 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecle 98 ++le+a+++ ++ + + + +lg++ + g+++ a e e FUN_002337-T1 457 KHLEIAKKVSDRVGEGSAYGNLGNAYESLGDFQKAIEYHE 496 67999********************999999999987655 PP == domain 7 score: -0.4 bits; conditional E-value: 1.5 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecle 98 ++le+a+e+ ++ + + + +lg++ + g+++ a e e FUN_002337-T1 497 KHLEIAKEVSDRVGEGNAYGNLGNAYESLGDFQNAIEYHE 536 5799999999999999999999999999999988877555 PP == domain 8 score: -1.1 bits; conditional E-value: 2.4 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecl 97 ++le+a+e+ ++ + + + +lg++ + g+++ a e FUN_002337-T1 537 KHLEIAKEVSHRVGEGSAYGNLGNTYQSLGDFRKAIEYH 575 579999999999999999999999999999998887755 PP == domain 9 score: -0.9 bits; conditional E-value: 2 TPR_COPA_B 58 lgklevalelakeadseqkwkqlgdlalkkgklklaeecle 98 ++le+a+e+ ++ + + + +lg++ + g+++ a e e FUN_002337-T1 616 EKDLEIAKEVGNRVGEGNAYGSLGNAYQSLGDFRKAIEYHE 656 468999*******************9999999998887655 PP == domain 10 score: -0.6 bits; conditional E-value: 1.7 TPR_COPA_B 58 lgklevalelakeadseqkwkqlgdlalkkgklklaee 95 ++le+a e+ ++ +e+ + +lg++ + g+++ a e FUN_002337-T1 696 EKHLEIAIEVGHRVGEENAYGSLGNAYESLGDFRKAIE 733 57899999999999999999999999999999988877 PP == domain 11 score: 3.1 bits; conditional E-value: 0.13 TPR_COPA_B 59 gklevalelakeadseqkwkqlgdlalkkgklklaeecleka 100 ++le+a+e+ ++ + + + +lg++ + g+++ a +c ek FUN_002337-T1 737 KHLEIAKEVSDRVGEGNAYGNLGNAYQSLGEFRKAIKCHEKH 778 689***********************************9885 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 1.4 1.9 1.4e+03 13 24 .. 86 97 .. 36 105 .. 0.54 2 ? 2.6 0.1 0.27 2.1e+02 5 28 .. 118 141 .. 116 147 .. 0.89 3 ? 2.0 0.1 0.42 3.2e+02 4 27 .. 157 180 .. 155 186 .. 0.87 4 ? 1.3 0.0 0.69 5.2e+02 5 27 .. 198 220 .. 196 225 .. 0.87 5 ? 4.0 0.0 0.1 76 5 31 .. 238 264 .. 236 269 .. 0.87 6 ? 1.0 0.1 0.86 6.4e+02 5 27 .. 278 300 .. 276 305 .. 0.87 7 ? -1.0 0.0 3.4 2.6e+03 7 27 .. 320 340 .. 317 345 .. 0.76 8 ? 2.7 0.1 0.25 1.9e+02 5 27 .. 358 380 .. 355 386 .. 0.88 9 ? 1.2 0.1 0.75 5.6e+02 5 31 .. 398 424 .. 396 429 .. 0.81 10 ? 2.3 0.0 0.33 2.5e+02 5 30 .. 438 463 .. 436 469 .. 0.86 11 ? 2.7 0.0 0.25 1.9e+02 5 30 .. 478 503 .. 476 509 .. 0.86 12 ? -0.1 0.1 1.8 1.4e+03 5 31 .. 518 544 .. 515 550 .. 0.84 13 ? 0.7 0.0 1 7.8e+02 5 29 .. 558 582 .. 555 588 .. 0.82 14 ? 0.7 0.0 1 7.7e+02 5 29 .. 598 622 .. 596 627 .. 0.83 15 ? 2.5 0.0 0.3 2.3e+02 5 27 .. 638 660 .. 636 665 .. 0.89 16 ? 1.0 0.0 0.83 6.2e+02 5 27 .. 678 700 .. 676 705 .. 0.89 17 ? 2.3 0.1 0.35 2.6e+02 5 31 .. 718 744 .. 716 780 .. 0.84 18 ? -0.1 0.0 1.9 1.4e+03 5 27 .. 798 820 .. 796 825 .. 0.80 19 ? 2.9 0.0 0.23 1.7e+02 5 28 .. 838 861 .. 836 900 .. 0.86 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 1.9 ARM_TT21_4th 13 HqYkkAinYYea 24 +++kAi+Y e+ FUN_002337-T1 86 GDFRKAIKYHEK 97 234444444444 PP == domain 2 score: 2.6 bits; conditional E-value: 0.27 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ lk+ FUN_002337-T1 118 LGNAYKSLGDFRKAIEYHEKHLKI 141 799999999**********99986 PP == domain 3 score: 2.0 bits; conditional E-value: 0.42 ARM_TT21_4th 4 kiGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002337-T1 157 NLGNAYRSLGDFRKAIEYHEKHLE 180 5899999999*********99876 PP == domain 4 score: 1.3 bits; conditional E-value: 0.69 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002337-T1 198 LGNAYRSLGDFRKAIEYHEKHLE 220 699999999*********99876 PP == domain 5 score: 4.0 bits; conditional E-value: 0.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksseq 31 +G+a+ +++kAi+Y e+ l++ ++ FUN_002337-T1 238 LGNAYQSLGDFRKAIEYHEKHLEIAKE 264 799****************99987765 PP == domain 6 score: 1.0 bits; conditional E-value: 0.86 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y + l+ FUN_002337-T1 278 LGNAYQSLGDFRKAIEYHAKHLE 300 799**************987765 PP == domain 7 score: -1.0 bits; conditional E-value: 3.4 ARM_TT21_4th 7 qalvktHqYkkAinYYeaalk 27 a+ +++kAi+Y e+ l+ FUN_002337-T1 320 IAYDSLGDFRKAIEYHEKHLE 340 555566689*******99876 PP == domain 8 score: 2.7 bits; conditional E-value: 0.25 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002337-T1 358 LGNAYQSLGDFRKAIEYHEKHLE 380 799***************99876 PP == domain 9 score: 1.2 bits; conditional E-value: 0.75 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksseq 31 +G a+ +++kAi+Y e+ l++ ++ FUN_002337-T1 398 LGIAYHSLGDFRKAIEYHEKHLEIAKE 424 5777778889*********99987665 PP == domain 10 score: 2.3 bits; conditional E-value: 0.33 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002337-T1 438 LGNAYESLGDFRKAIEYHEKHLEIAK 463 799999999**********9988766 PP == domain 11 score: 2.7 bits; conditional E-value: 0.25 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002337-T1 478 LGNAYESLGDFQKAIEYHEKHLEIAK 503 799999999**********9988765 PP == domain 12 score: -0.1 bits; conditional E-value: 1.8 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksseq 31 +G+a+ +++ Ai+Y e+ l++ ++ FUN_002337-T1 518 LGNAYESLGDFQNAIEYHEKHLEIAKE 544 7999999999*********99887765 PP == domain 13 score: 0.7 bits; conditional E-value: 1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+++ +++kAi+Y e+ l++ FUN_002337-T1 558 LGNTYQSLGDFRKAIEYHEKDLEIA 582 6888888889********9988765 PP == domain 14 score: 0.7 bits; conditional E-value: 1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G a+ +++kAi+Y e+ l++ FUN_002337-T1 598 LGIAYQSLGDFRKAIEYHEKDLEIA 622 6888888999********9987765 PP == domain 15 score: 2.5 bits; conditional E-value: 0.3 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002337-T1 638 LGNAYQSLGDFRKAIEYHEKHLE 660 799***************99876 PP == domain 16 score: 1.0 bits; conditional E-value: 0.83 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi Y e+ l+ FUN_002337-T1 678 LGNAYQSLGDFRKAIGYHEKHLE 700 799***************99876 PP == domain 17 score: 2.3 bits; conditional E-value: 0.35 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksseq 31 +G+a+ +++kAi+Y e+ l++ ++ FUN_002337-T1 718 LGNAYESLGDFRKAIEYHEKHLEIAKE 744 6899999999*********99887664 PP == domain 18 score: -0.1 bits; conditional E-value: 1.9 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ + + Ai+YYe+ l+ FUN_002337-T1 798 LGNAYQSLGDVREAIEYYEKHLE 820 67888888888899999998776 PP == domain 19 score: 2.9 bits; conditional E-value: 0.23 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ l++ FUN_002337-T1 838 LGNAYQSLGDFRKAIEYHEKHLEI 861 799***************998764 PP >> DHR-2_Lobe_A DHR-2, Lobe A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.1 3.8 2.8e+03 88 152 .. 27 92 .. 12 93 .. 0.76 2 ? 0.7 0.0 1.1 8.6e+02 108 152 .. 248 292 .. 234 293 .. 0.85 3 ? 0.1 0.0 1.7 1.3e+03 111 152 .. 411 452 .. 401 454 .. 0.87 4 ? 2.0 0.0 0.46 3.4e+02 103 152 .. 483 532 .. 476 534 .. 0.85 5 ? 1.6 0.0 0.58 4.3e+02 103 152 .. 523 572 .. 496 574 .. 0.85 6 ? -1.9 0.0 7.3 5.5e+03 112 152 .. 612 652 .. 602 667 .. 0.83 7 ? 1.9 0.0 0.47 3.5e+02 107 152 .. 727 772 .. 711 773 .. 0.84 8 ? -1.9 0.0 7.2 5.4e+03 111 152 .. 811 852 .. 798 853 .. 0.80 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 3.8 DHR-2_Lobe_A 88 cdseqftesglvelleeaidylkka.elyElaielyklllpiyekkrdYkklseihkklaelyeki 152 c+se + g+ ++ + y++ka e++E ++ ++ +++ Y++l+++++ l ++ + i FUN_002337-T1 27 CESEIANAYGYTSIAFHSQGYFRKAiEYHEKHLKITMEVGDRAGEEKGYQNLAHAFQSLGDFRKAI 92 555555556666666666678887768889999999999999999999*****9999999887765 PP == domain 2 score: 0.7 bits; conditional E-value: 1.1 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + k e++E e+ k+++ + ++Y +l ++++ l ++ + i FUN_002337-T1 248 FRKAIEYHEKHLEIAKEASDRVGEGNAYGNLGNAYQSLGDFRKAI 292 55666999****************************999987765 PP == domain 3 score: 0.1 bits; conditional E-value: 1.7 DHR-2_Lobe_A 111 kaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e++E e+ k+++ + +Y +l ++++ l ++ + i FUN_002337-T1 411 AIEYHEKHLEIAKEVSHRVGEGSAYGNLGNAYESLGDFRKAI 452 45899****************************999987766 PP == domain 4 score: 2.0 bits; conditional E-value: 0.46 DHR-2_Lobe_A 103 eeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e+ d+ k e++E e+ k+++ + ++Y +l ++++ l ++ + i FUN_002337-T1 483 ESLGDFQKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGNAYESLGDFQNAI 532 555667778899****************************9999987766 PP == domain 5 score: 1.6 bits; conditional E-value: 0.58 DHR-2_Lobe_A 103 eeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e+ d+ + e++E e+ k+++ + +Y +l ++++ l ++ + i FUN_002337-T1 523 ESLGDFQNAIEYHEKHLEIAKEVSHRVGEGSAYGNLGNTYQSLGDFRKAI 572 55556667779999999999999999999999999999999999887766 PP == domain 6 score: -1.9 bits; conditional E-value: 7.3 DHR-2_Lobe_A 112 aelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e++E e+ k++ + ++Y +l ++++ l ++ + i FUN_002337-T1 612 IEYHEKDLEIAKEVGNRVGEGNAYGSLGNAYQSLGDFRKAI 652 47888888888999899999999999999999998887665 PP == domain 7 score: 1.9 bits; conditional E-value: 0.47 DHR-2_Lobe_A 107 dylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 d+ k e++E e+ k+++ + ++Y +l ++++ l e+ + i FUN_002337-T1 727 DFRKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGNAYQSLGEFRKAI 772 556667999****************************999987766 PP == domain 8 score: -1.9 bits; conditional E-value: 7.2 DHR-2_Lobe_A 111 kaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e+yE e+ ++ + ++Y +l ++++ l ++ + i FUN_002337-T1 811 AIEYYEKHLEIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAI 852 558899999999999999999999999999999998887665 PP >> FbpC_C_terminal FbpC C-terminal regulatory nucleotide binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.1 0.0 1.6 1.2e+03 11 25 .. 175 189 .. 172 190 .. 0.92 2 ? 0.0 0.0 1.8 1.3e+03 11 25 .. 215 229 .. 212 231 .. 0.92 3 ? 2.1 0.0 0.4 3e+02 11 25 .. 295 309 .. 291 313 .. 0.92 4 ? -1.3 0.0 4.7 3.5e+03 11 25 .. 335 349 .. 333 351 .. 0.90 5 ? 0.4 0.0 1.3 1e+03 11 25 .. 655 669 .. 652 673 .. 0.90 6 ? 2.0 0.0 0.43 3.2e+02 9 27 .. 693 711 .. 690 715 .. 0.84 7 ? 2.0 0.0 0.42 3.2e+02 11 25 .. 775 789 .. 771 793 .. 0.90 8 ? -1.5 0.0 5.3 4e+03 13 25 .. 817 829 .. 815 831 .. 0.91 9 ? -2.0 0.0 7.9 5.9e+03 11 24 .. 855 868 .. 853 869 .. 0.89 Alignments for each domain: == domain 1 score: 0.1 bits; conditional E-value: 1.6 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002337-T1 175 HEKHLEIAIEVGNRV 189 789*********998 PP == domain 2 score: 0.0 bits; conditional E-value: 1.8 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002337-T1 215 HEKHLEIAVEVGHRV 229 789*********998 PP == domain 3 score: 2.1 bits; conditional E-value: 0.4 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002337-T1 295 HAKHLEIAIEVGNRV 309 89***********98 PP == domain 4 score: -1.3 bits; conditional E-value: 4.7 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G ++ FUN_002337-T1 335 HEKHLEIAIEVGHRI 349 789*********986 PP == domain 5 score: 0.4 bits; conditional E-value: 1.3 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002337-T1 655 HEKHLEIAIEVGNRV 669 789*********998 PP == domain 6 score: 2.0 bits; conditional E-value: 0.43 FbpC_C_terminal 9 tPkaRhvEiSlraGqtVlT 27 + + +h Ei++++G +V FUN_002337-T1 693 GYHEKHLEIAIEVGHRVGE 711 56899***********965 PP == domain 7 score: 2.0 bits; conditional E-value: 0.42 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002337-T1 775 HEKHLEIAIDVGHRV 789 889**********98 PP == domain 8 score: -1.5 bits; conditional E-value: 5.3 FbpC_C_terminal 13 RhvEiSlraGqtV 25 +h Ei++++G +V FUN_002337-T1 817 KHLEIAIEVGHRV 829 799*******998 PP == domain 9 score: -2.0 bits; conditional E-value: 7.9 FbpC_C_terminal 11 kaRhvEiSlraGqt 24 + +h Ei++++G + FUN_002337-T1 855 HEKHLEIAIEVGNR 868 789*********87 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1365 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 608 (0.0238011); expected 510.9 (0.02) Passed bias filter: 550 (0.0215306); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 34 [number of targets reported over threshold] # CPU time: 0.65u 0.43s 00:00:01.08 Elapsed: 00:00:00.51 # Mc/sec: 10882.89 // Query: FUN_002338-T1 [L=265] Description: FUN_002338 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-41 142.6 0.1 1.9e-41 142.3 0.1 1.1 1 Proteasome Proteasome subunit 1e-05 25.3 1.3 1.8e-05 24.5 1.3 1.4 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 142.3 0.1 1.5e-45 1.9e-41 14 189 .] 65 233 .. 63 233 .. 0.96 Alignments for each domain: == domain 1 score: 142.3 bits; conditional E-value: 1.5e-45 Proteasome 14 dgvvlaadkratagskllskdtveKifkiddhigvafaGlaaDartlvdyaraeaqlyrlrygepisvelvkrvaaklqaytqrsgrrpfgvslli 109 dgv+l+ad+rat+ ++ ++++++Ki+ i ++i+++ aG aaD++++++++++++ql++l++g + ++ +a +++++ + ++++++ ++l++ FUN_002338-T1 65 DGVILGADTRATEDTIV-ADKNCSKIHYIAPNIYCCGAGIAADTEYVTQLISSNIQLHSLSTGCQARIV----TALRMLKQRLFRYQGYISAALVL 155 9***********76666.6666***********************************************....9999999999999********** PP Proteasome 110 agvdeegkprLyqidpsGsvieykdavaiGsgsqaaygvlekeykedltleeavelakkalkealerdklsgknievavi 189 +gv+ +g p L ++ p+Gs+ + ++v +G+gs aa++v+e+++k+d++l+ea++l+++a+ + + +d sg+n+++++i FUN_002338-T1 156 GGVNLNG-PTLHTVYPHGSTDKL-PYVTMGYGSLAAMSVFESRCKPDMELDEAKKLVRDAIAAGIFHDLGSGSNVDLCII 233 ****777.***************.8*****************************************************97 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 1.3 1.4e-09 1.8e-05 1 18 [. 247 264 .. 247 265 .] 0.96 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.4e-09 Pr_beta_C 1 PNergeRqgsYkfkrGTT 18 +N +g Rqg+Y +krGTT FUN_002338-T1 247 ANDKGVRQGRYSYKRGTT 264 8***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (265 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 622 (0.0243492); expected 510.9 (0.02) Passed bias filter: 596 (0.0233314); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2629.44 // Query: FUN_002339-T1 [L=1605] Description: FUN_002339 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-239 774.1 61.9 7.8e-17 61.7 0.1 15.7 17 TPR_12 Tetratricopeptide repeat 6e-238 749.5 47.4 1.1e-07 31.9 0.0 28.5 28 TPR_7 Tetratricopeptide repeat 3.1e-204 654.0 147.8 2.5e-07 30.7 0.4 29.5 29 TPR_1 Tetratricopeptide repeat 1.6e-133 431.9 44.1 0.00032 21.1 0.0 28.2 28 TPR_10 Tetratricopeptide repeat 7.5e-128 406.5 116.7 0.00052 20.4 0.2 28.0 27 TPR_8 Tetratricopeptide repeat 9.7e-83 266.0 125.1 0.019 15.6 0.1 29.6 30 TPR_2 Tetratricopeptide repeat 3.2e-50 171.7 0.0 4.9e-50 171.1 0.0 1.2 1 CHAT CHAT domain 7.4e-45 147.2 49.7 14 7.2 0.0 28.7 29 TPR_14 Tetratricopeptide repeat 4e-42 139.4 62.1 5.5 8.0 0.1 27.6 27 TPR_17 Tetratricopeptide repeat 4.7e-40 136.0 64.2 0.12 13.0 0.0 26.9 27 Rapsyn_N Rapsyn N-terminal myristoylation and linker 2.1e-33 116.5 0.4 0.00012 22.0 0.0 8.6 12 TPR_MalT MalT-like TPR region 6.5e-22 77.1 33.2 1.9e+02 3.6 0.0 25.5 26 TPR_6 Tetratricopeptide repeat 8.5e-21 75.1 15.8 0.043 13.8 0.0 8.3 11 SNAP Soluble NSF attachment protein, SNAP 1.5e-20 73.5 0.0 99 3.6 0.0 23.5 28 DUF2977 Protein of unknown function (DUF2977) 1.4e-19 70.6 52.2 2.2 9.3 0.2 19.8 23 TPR_16 Tetratricopeptide repeat 2.1e-19 69.5 29.5 80 3.5 0.0 24.2 27 DUF7542 Family of unknown function (DUF7542) 1.8e-18 66.4 0.7 62 3.8 0.0 21.4 26 DBD_Tnp_Mut MuDR family transposase 1.3e-16 61.3 47.7 19 5.3 0.2 23.3 26 RPN7 26S proteasome subunit RPN7 1.3e-12 48.2 23.1 1.1e+02 2.6 0.0 21.3 26 TPR_15 Tetratricopeptide repeat 2.6e-12 46.6 6.0 2.6e+02 3.2 0.0 18.0 17 TPR_4 Tetratricopeptide repeat 3.5e-12 46.7 10.1 8.3 6.2 0.1 11.6 16 TPR_NPHP3 Nephrocystin-3 TPR domain 1.9e-10 41.7 50.4 98 3.7 0.0 23.9 28 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth A 5.6e-10 38.9 20.3 1.7 7.6 0.5 12.4 11 TPR_IF140-IFT172 IF140/IFT172 TPR domain 1.4e-09 38.0 60.0 33 5.5 0.0 24.7 28 PPR PPR repeat 7.5e-08 33.1 35.6 39 5.1 0.1 16.1 19 TPR_19 Tetratricopeptide repeat 2.7e-06 27.3 0.2 26 4.3 0.0 8.2 11 Sec1 Sec1 family 0.00041 21.1 0.0 99 3.7 0.0 9.7 11 NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisob 0.0025 18.5 35.2 93 3.8 0.0 17.7 22 GGDEF_2 GGDEF-like domain ------ inclusion threshold ------ 0.014 15.6 96.4 21 5.4 0.1 24.7 27 TPR_11 TPR repeat 0.88 10.4 18.2 1.6e+02 3.2 0.1 9.0 8 CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA recept Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 0.1 2.6e-10 2.2e-07 14 75 .. 3 62 .. 1 64 [. 0.95 2 ! 61.5 0.2 1.1e-19 9.1e-17 4 77 .] 73 144 .. 70 144 .. 0.97 3 ! 58.4 0.1 1e-18 8.7e-16 4 75 .. 153 222 .. 150 224 .. 0.96 4 ! 59.6 0.3 4.3e-19 3.7e-16 4 75 .. 233 302 .. 230 304 .. 0.96 5 ! 58.3 0.1 1.1e-18 9.1e-16 4 75 .. 313 382 .. 310 384 .. 0.96 6 ! 59.6 0.3 4.3e-19 3.7e-16 4 75 .. 393 462 .. 390 464 .. 0.96 7 ! 61.4 0.3 1.2e-19 1e-16 4 77 .] 473 544 .. 470 544 .. 0.97 8 ! 51.3 0.2 1.6e-16 1.4e-13 16 77 .] 525 584 .. 524 584 .. 0.97 9 ! 60.3 0.5 2.5e-19 2.1e-16 4 75 .. 553 622 .. 550 624 .. 0.96 10 ! 59.0 0.1 6.5e-19 5.5e-16 4 75 .. 593 662 .. 590 664 .. 0.96 11 ! 61.5 0.2 1.1e-19 9.2e-17 4 75 .. 633 702 .. 630 704 .. 0.96 12 ! 55.7 0.4 6.8e-18 5.8e-15 4 75 .. 673 742 .. 670 744 .. 0.96 13 ! 61.4 0.3 1.2e-19 9.9e-17 4 77 .] 753 824 .. 750 824 .. 0.97 14 ! 60.6 0.3 2.1e-19 1.8e-16 4 75 .. 833 902 .. 830 904 .. 0.96 15 ! 54.2 0.2 2e-17 1.7e-14 5 77 .] 914 984 .. 910 984 .. 0.96 16 ! 61.7 0.1 9.1e-20 7.8e-17 5 77 .] 994 1064 .. 991 1064 .. 0.97 17 ! 39.2 0.0 9.7e-13 8.3e-10 4 75 .. 1073 1142 .. 1071 1144 .. 0.95 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 2.6e-10 TPR_12 14 rrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 + +g + +A+e++ek l + ++ +d+ ++ ++nL+ +++ gd+++A++++e+ leia FUN_002339-T1 3 FIQGCFRKAIEYHEKHLKITMEV--GDRAGEEKGYQNLAYAFQSHGDFRKAIKYHEKHLEIA 62 569********************..99*********************************98 PP == domain 2 score: 61.5 bits; conditional E-value: 1.1e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+++ + lg++ +A+e++ek le+a+++ d+ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002339-T1 73 NAYGNLGNAFQSLGDFRKAIEYHEKHLEIAKEV--SDRFGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 144 799******************************..99999*******************************986 PP == domain 3 score: 58.4 bits; conditional E-value: 1e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek l +a ++ +++ ++ a+ Lg++y+ lgd+++A+e++e+ leia FUN_002339-T1 153 SAYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEV--GHRVGEGSAYGSLGTVYQSLGDFRKAIEYHEKHLEIA 222 7899*****************************..99*********************************98 PP == domain 4 score: 59.6 bits; conditional E-value: 4.3e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++r lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y lgd+++A+e++e+ leia FUN_002339-T1 233 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 302 799******************************..99*********************************98 PP == domain 5 score: 58.3 bits; conditional E-value: 1.1e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++r lg++ +A+e++ek l +a ++ +++ ++ a+ Lg++y+ lgd+++A+e++e+ leia FUN_002339-T1 313 NAYGNLGNAYRSLGDFRKAIEYHEKHLKIAIEV--GHRVGEGSAYGSLGTVYQSLGDFRKAIEYHEKHLEIA 382 799******************************..99*********************************98 PP == domain 6 score: 59.6 bits; conditional E-value: 4.3e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++r lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y lgd+++A+e++e+ leia FUN_002339-T1 393 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 462 799******************************..99*********************************98 PP == domain 7 score: 61.4 bits; conditional E-value: 1.2e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl++++r lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y lgd+++A+e++e+ leia+k FUN_002339-T1 473 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKK 544 799******************************..99**********************************996 PP == domain 8 score: 51.3 bits; conditional E-value: 1.6e-16 TPR_12 16 lgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 lg++ +A+e++ek le+a+++ +d+ ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002339-T1 525 LGDFRKAIEYHEKHLEIAKKV--GDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 584 79*******************..9***********************************986 PP == domain 9 score: 60.3 bits; conditional E-value: 2.5e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a+++ d+ + a+ nLg +y+ lgd+++A+e++e+ l+ia FUN_002339-T1 553 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLKIA 622 7999*****************************..9**********************************98 PP == domain 10 score: 59.0 bits; conditional E-value: 6.5e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek l +a ++ +++ ++ a+ Lg++y+ lgd+++A+e++e+ leia FUN_002339-T1 593 SAYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEV--GHRVGEGSAYGSLGTVYRSLGDFRKAIEYHEKHLEIA 662 7899*****************************..99*********************************98 PP == domain 11 score: 61.5 bits; conditional E-value: 1.1e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l+ v+r lg++ +A+e++ek le+a ++ +++ ++ +a+ nLg +y+ lgd+++A+e++e+ leia FUN_002339-T1 633 SAYGSLGTVYRSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEIA 702 68888****************************..99*********************************98 PP == domain 12 score: 55.7 bits; conditional E-value: 6.8e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl++++r lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y lgd+++A+e++e+ leia FUN_002339-T1 673 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKQLEIA 742 799******************************..99******************************99997 PP == domain 13 score: 61.4 bits; conditional E-value: 1.2e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl++++r lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y lgd+++A+e++e+ leia+k FUN_002339-T1 753 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKK 824 799******************************..99**********************************996 PP == domain 14 score: 60.6 bits; conditional E-value: 2.1e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a+++ d+ ++ a+ nLg +y++lgd+++A+e++e+ leia FUN_002339-T1 833 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGGAYGNLGNAYQTLGDFQKAIEYHEKHLEIA 902 7999*****************************..9**********************************98 PP == domain 15 score: 54.2 bits; conditional E-value: 2e-17 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ l++++r lg++ +A+e++ek le+a ++ d ++ a+ nLg +y+ lgd+++A+e++e+ leia++ FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHEKDLEIAIEV--SDQVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 984 6778****************************..9***********************************986 PP == domain 16 score: 61.7 bits; conditional E-value: 9.1e-20 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+++++ lg++ +A+e++ek+le+a ++ d+ ++ +a+ Lg +y lgd+++A+e++e+ leia+k FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIEYHEKSLEIAIEV--SDRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKK 1064 799*****************************..9***********************************996 PP == domain 17 score: 39.2 bits; conditional E-value: 9.7e-13 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+ +++ +g++ +A+e++ek l++a +l +++ ++ +++n+g ++ lg++e Al+ + a+e++ FUN_002339-T1 1073 SAYGNLGIAYQSMGEFRKAIEYHEKHLQIAIEL--GNRAGEGMSHHNIGNGFFSLGQFEIALDKFVSAVEAF 1142 6899****************************9..99**************************999999886 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.8 0.0 0.0068 5.8 15 36 .] 8 29 .. 5 29 .. 0.90 2 ! 17.8 0.0 4.3e-06 0.0036 3 35 .. 36 68 .. 35 69 .. 0.91 3 ! 29.2 0.0 9.4e-10 8e-07 1 35 [. 74 108 .. 74 109 .. 0.96 4 ! 31.9 0.0 1.2e-10 1.1e-07 1 35 [. 114 148 .. 114 149 .. 0.96 5 ! 26.7 0.0 5.6e-09 4.8e-06 1 35 [. 154 188 .. 154 189 .. 0.93 6 ! 24.0 0.0 4.2e-08 3.6e-05 1 35 [. 194 228 .. 194 229 .. 0.92 7 ! 30.1 0.0 4.8e-10 4.1e-07 1 35 [. 234 268 .. 234 269 .. 0.94 8 ! 26.0 0.0 9.9e-09 8.4e-06 1 35 [. 274 308 .. 274 309 .. 0.93 9 ! 28.2 0.0 1.9e-09 1.6e-06 1 35 [. 314 348 .. 314 349 .. 0.93 10 ! 24.0 0.0 4.2e-08 3.6e-05 1 35 [. 354 388 .. 354 389 .. 0.92 11 ! 30.1 0.0 4.8e-10 4.1e-07 1 35 [. 394 428 .. 394 429 .. 0.94 12 ! 26.0 0.0 9.9e-09 8.4e-06 1 35 [. 434 468 .. 434 469 .. 0.93 13 ! 30.1 0.0 4.8e-10 4.1e-07 1 35 [. 474 508 .. 474 509 .. 0.94 14 ! 30.0 0.0 4.9e-10 4.2e-07 1 35 [. 514 548 .. 514 549 .. 0.96 15 ! 31.9 0.0 1.2e-10 1.1e-07 1 35 [. 554 588 .. 554 589 .. 0.96 16 ! 26.7 0.0 5.6e-09 4.8e-06 1 35 [. 594 628 .. 594 629 .. 0.93 17 ! 25.5 0.0 1.4e-08 1.2e-05 1 35 [. 634 668 .. 634 669 .. 0.92 18 ! 30.1 0.0 4.8e-10 4.1e-07 1 35 [. 674 708 .. 674 709 .. 0.94 19 ! 26.1 0.0 8.9e-09 7.6e-06 1 35 [. 714 748 .. 714 749 .. 0.93 20 ! 30.1 0.0 4.8e-10 4.1e-07 1 35 [. 754 788 .. 754 789 .. 0.94 21 ! 29.2 0.0 9.3e-10 7.9e-07 1 35 [. 794 828 .. 794 829 .. 0.95 22 ! 31.9 0.0 1.2e-10 1.1e-07 1 35 [. 834 868 .. 834 869 .. 0.96 23 ! 28.9 0.0 1.2e-09 9.8e-07 1 35 [. 874 908 .. 874 909 .. 0.95 24 ! 25.6 0.0 1.3e-08 1.1e-05 1 34 [. 914 947 .. 914 949 .. 0.91 25 ! 29.0 0.1 1e-09 8.7e-07 1 32 [. 954 985 .. 954 988 .. 0.94 26 ! 23.7 0.0 5.3e-08 4.5e-05 1 35 [. 994 1028 .. 994 1029 .. 0.94 27 ! 29.2 0.0 9.3e-10 7.9e-07 1 35 [. 1034 1068 .. 1034 1069 .. 0.95 28 ! 25.9 0.0 1.1e-08 9.1e-06 1 35 [. 1074 1108 .. 1074 1109 .. 0.94 Alignments for each domain: == domain 1 score: 7.8 bits; conditional E-value: 0.0068 TPR_7 15 ydeAirlyerlLalakdpedre 36 +++Ai+++e++L ++++ +dr+ FUN_002339-T1 8 FRKAIEYHEKHLKITMEVGDRA 29 789****************995 PP == domain 2 score: 17.8 bits; conditional E-value: 4.3e-06 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La ++++ Gd+++Ai+++e++L++a + ++r FUN_002339-T1 36 QNLAYAFQSHGDFRKAIKYHEKHLEIAIEAGHR 68 69************************9887776 PP == domain 3 score: 29.2 bits; conditional E-value: 9.4e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L++++++lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 74 AYGNLGNAFQSLGDFRKAIEYHEKHLEIAKEVSDR 108 789****************************9997 PP == domain 4 score: 31.9 bits; conditional E-value: 1.2e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 114 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 148 789****************************9998 PP == domain 5 score: 26.7 bits; conditional E-value: 5.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L +a + ++r FUN_002339-T1 154 AYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEVGHR 188 789************************99888876 PP == domain 6 score: 24.0 bits; conditional E-value: 4.2e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L++a + ++r FUN_002339-T1 194 AYGSLGTVYQSLGDFRKAIEYHEKHLEIAIEVGNR 228 6889************************9888876 PP == domain 7 score: 30.1 bits; conditional E-value: 4.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002339-T1 234 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHR 268 789*************************9988876 PP == domain 8 score: 26.0 bits; conditional E-value: 9.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++a + ++r FUN_002339-T1 274 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAIEVGNR 308 7899************************9888876 PP == domain 9 score: 28.2 bits; conditional E-value: 1.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L +a + ++r FUN_002339-T1 314 AYGNLGNAYRSLGDFRKAIEYHEKHLKIAIEVGHR 348 789************************99888876 PP == domain 10 score: 24.0 bits; conditional E-value: 4.2e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L++a + ++r FUN_002339-T1 354 AYGSLGTVYQSLGDFRKAIEYHEKHLEIAIEVGNR 388 6889************************9888876 PP == domain 11 score: 30.1 bits; conditional E-value: 4.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002339-T1 394 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHR 428 789*************************9988876 PP == domain 12 score: 26.0 bits; conditional E-value: 9.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++a + ++r FUN_002339-T1 434 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAIEVGNR 468 7899************************9888876 PP == domain 13 score: 30.1 bits; conditional E-value: 4.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002339-T1 474 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHR 508 789*************************9988876 PP == domain 14 score: 30.0 bits; conditional E-value: 4.9e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 514 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVGDR 548 7899****************************998 PP == domain 15 score: 31.9 bits; conditional E-value: 1.2e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 554 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 588 789****************************9998 PP == domain 16 score: 26.7 bits; conditional E-value: 5.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L +a + ++r FUN_002339-T1 594 AYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEVGHR 628 789************************99888876 PP == domain 17 score: 25.5 bits; conditional E-value: 1.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +yr+lGd+++Ai+++e++L++a + ++r FUN_002339-T1 634 AYGSLGTVYRSLGDFRKAIEYHEKHLEIAIEVGNR 668 7899************************9888876 PP == domain 18 score: 30.1 bits; conditional E-value: 4.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002339-T1 674 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHR 708 789*************************9988876 PP == domain 19 score: 26.1 bits; conditional E-value: 8.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++a + ++r FUN_002339-T1 714 AYGSLGNAYDSLGDFRKAIEYHEKQLEIAIEVGNR 748 7899************************9888876 PP == domain 20 score: 30.1 bits; conditional E-value: 4.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002339-T1 754 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHR 788 789*************************9988876 PP == domain 21 score: 29.2 bits; conditional E-value: 9.3e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 794 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSDR 828 7899***************************9998 PP == domain 22 score: 31.9 bits; conditional E-value: 1.2e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 834 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 868 789****************************9998 PP == domain 23 score: 28.9 bits; conditional E-value: 1.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd+++Ai+++e++L++a + +dr FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIEYHEKHLEIAIEVGDR 908 789**************************999997 PP == domain 24 score: 25.6 bits; conditional E-value: 1.3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L+++yr+lGd+++Ai+++e+ L++a + +d FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHEKDLEIAIEVSD 947 7899***********************9977766 PP == domain 25 score: 29.0 bits; conditional E-value: 1e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdp 32 a+++L+++y++lGd+++Ai+++e++L++ak+ FUN_002339-T1 954 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 985 789**************************975 PP == domain 26 score: 23.7 bits; conditional E-value: 5.3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L++++++lGd+++Ai+++e+ L++a + +dr FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIEYHEKSLEIAIEVSDR 1028 789*************************9988887 PP == domain 27 score: 29.2 bits; conditional E-value: 9.3e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++ak+ +dr FUN_002339-T1 1034 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSDR 1068 7899***************************9998 PP == domain 28 score: 25.9 bits; conditional E-value: 1.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y+++G++++Ai+++e++L++a ++++r FUN_002339-T1 1074 AYGNLGIAYQSMGEFRKAIEYHEKHLQIAIELGNR 1108 789**************************999887 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.1 0.039 34 13 30 .. 4 21 .. 3 21 .. 0.89 2 ! 17.1 0.8 5.8e-06 0.005 2 30 .. 33 61 .. 32 62 .. 0.94 3 ! 28.3 0.3 1.7e-09 1.5e-06 2 31 .. 73 102 .. 72 104 .. 0.94 4 ! 30.7 0.4 2.9e-10 2.5e-07 3 31 .. 114 142 .. 112 144 .. 0.94 5 ! 29.4 0.4 7.3e-10 6.2e-07 3 30 .. 154 181 .. 152 182 .. 0.95 6 ! 23.1 0.0 7.3e-08 6.2e-05 3 30 .. 194 221 .. 192 222 .. 0.95 7 ! 30.4 0.5 3.7e-10 3.1e-07 2 30 .. 233 261 .. 232 262 .. 0.95 8 ! 25.9 0.2 1e-08 8.5e-06 2 30 .. 273 301 .. 272 302 .. 0.95 9 ! 29.7 0.5 6.2e-10 5.3e-07 2 30 .. 313 341 .. 312 342 .. 0.95 10 ! 23.1 0.0 7.3e-08 6.2e-05 3 30 .. 354 381 .. 352 382 .. 0.95 11 ! 30.4 0.5 3.7e-10 3.1e-07 2 30 .. 393 421 .. 392 422 .. 0.95 12 ! 25.9 0.2 1e-08 8.5e-06 2 30 .. 433 461 .. 432 462 .. 0.95 13 ! 30.4 0.5 3.7e-10 3.1e-07 2 30 .. 473 501 .. 472 502 .. 0.95 14 ! 26.4 0.3 6.5e-09 5.6e-06 2 31 .. 513 542 .. 512 544 .. 0.94 15 ! 30.7 0.4 2.9e-10 2.5e-07 3 31 .. 554 582 .. 552 584 .. 0.94 16 ! 29.4 0.4 7.3e-10 6.2e-07 3 30 .. 594 621 .. 592 622 .. 0.95 17 ! 23.1 0.0 7.3e-08 6.2e-05 3 30 .. 634 661 .. 632 662 .. 0.95 18 ! 30.4 0.5 3.7e-10 3.1e-07 2 30 .. 673 701 .. 672 702 .. 0.95 19 ! 21.4 0.3 2.6e-07 0.00022 2 26 .. 713 737 .. 712 742 .. 0.90 20 ! 30.4 0.5 3.7e-10 3.1e-07 2 30 .. 753 781 .. 752 782 .. 0.95 21 ! 26.4 0.3 6.5e-09 5.6e-06 2 31 .. 793 822 .. 792 824 .. 0.94 22 ! 30.7 0.4 2.9e-10 2.5e-07 3 31 .. 834 862 .. 832 864 .. 0.94 23 ! 29.3 0.6 8.1e-10 6.9e-07 3 30 .. 874 901 .. 873 902 .. 0.96 24 ! 21.2 0.2 2.9e-07 0.00025 3 26 .. 914 937 .. 913 942 .. 0.93 25 ! 30.7 0.4 2.9e-10 2.5e-07 3 31 .. 954 982 .. 952 984 .. 0.94 26 ! 28.4 0.2 1.6e-09 1.4e-06 3 30 .. 994 1021 .. 993 1022 .. 0.97 27 ! 26.4 0.3 6.5e-09 5.6e-06 2 31 .. 1033 1062 .. 1032 1064 .. 0.94 28 ! 26.9 0.2 4.8e-09 4.1e-06 3 30 .. 1074 1101 .. 1072 1102 .. 0.95 29 ? 6.8 0.0 0.011 9.1 4 27 .. 1115 1138 .. 1113 1141 .. 0.85 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.039 TPR_1 13 klgkydeAleyyekALel 30 +g + +A+ey ek L++ FUN_002339-T1 4 IQGCFRKAIEYHEKHLKI 21 6999**********9987 PP == domain 2 score: 17.1 bits; conditional E-value: 5.8e-06 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k + nl++a+++ g++ +A++y ek Le+ FUN_002339-T1 33 KGYQNLAYAFQSHGDFRKAIKYHEKHLEI 61 5799***********************98 PP == domain 3 score: 28.3 bits; conditional E-value: 1.7e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGna+++lg++ +A+ey ek Le+ FUN_002339-T1 73 NAYGNLGNAFQSLGDFRKAIEYHEKHLEIA 102 69**************************96 PP == domain 4 score: 30.7 bits; conditional E-value: 2.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 114 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 142 9**************************96 PP == domain 5 score: 29.4 bits; conditional E-value: 7.3e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A+ey ek L++ FUN_002339-T1 154 AYGNLGNAYQSLGDFRKAIEYHEKHLKI 181 9*************************98 PP == domain 6 score: 23.1 bits; conditional E-value: 7.3e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lG +y++lg++ +A+ey ek Le+ FUN_002339-T1 194 AYGSLGTVYQSLGDFRKAIEYHEKHLEI 221 89************************98 PP == domain 7 score: 30.4 bits; conditional E-value: 3.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 233 NAYGNLGNAYRSLGDFRKAIEYHEKHLEI 261 69*************************98 PP == domain 8 score: 25.9 bits; conditional E-value: 1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002339-T1 273 NAYGSLGNAYDSLGDFRKAIEYHEKHLEI 301 59*************************98 PP == domain 9 score: 29.7 bits; conditional E-value: 6.2e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek L++ FUN_002339-T1 313 NAYGNLGNAYRSLGDFRKAIEYHEKHLKI 341 69*************************98 PP == domain 10 score: 23.1 bits; conditional E-value: 7.3e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lG +y++lg++ +A+ey ek Le+ FUN_002339-T1 354 AYGSLGTVYQSLGDFRKAIEYHEKHLEI 381 89************************98 PP == domain 11 score: 30.4 bits; conditional E-value: 3.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 393 NAYGNLGNAYRSLGDFRKAIEYHEKHLEI 421 69*************************98 PP == domain 12 score: 25.9 bits; conditional E-value: 1e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002339-T1 433 NAYGSLGNAYDSLGDFRKAIEYHEKHLEI 461 59*************************98 PP == domain 13 score: 30.4 bits; conditional E-value: 3.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 473 NAYGNLGNAYRSLGDFRKAIEYHEKHLEI 501 69*************************98 PP == domain 14 score: 26.4 bits; conditional E-value: 6.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002339-T1 513 NAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 542 59**************************96 PP == domain 15 score: 30.7 bits; conditional E-value: 2.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 554 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 582 9**************************96 PP == domain 16 score: 29.4 bits; conditional E-value: 7.3e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++lg++ +A+ey ek L++ FUN_002339-T1 594 AYGNLGNAYQSLGDFRKAIEYHEKHLKI 621 9*************************98 PP == domain 17 score: 23.1 bits; conditional E-value: 7.3e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lG +y++lg++ +A+ey ek Le+ FUN_002339-T1 634 AYGSLGTVYRSLGDFRKAIEYHEKHLEI 661 89************************98 PP == domain 18 score: 30.4 bits; conditional E-value: 3.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 673 NAYGNLGNAYRSLGDFRKAIEYHEKHLEI 701 69*************************98 PP == domain 19 score: 21.4 bits; conditional E-value: 2.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ lGnay +lg++ +A+ey ek FUN_002339-T1 713 NAYGSLGNAYDSLGDFRKAIEYHEK 737 59********************998 PP == domain 20 score: 30.4 bits; conditional E-value: 3.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 753 NAYGNLGNAYRSLGDFRKAIEYHEKHLEI 781 69*************************98 PP == domain 21 score: 26.4 bits; conditional E-value: 6.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002339-T1 793 NAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 822 59**************************96 PP == domain 22 score: 30.7 bits; conditional E-value: 2.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 834 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 862 9**************************96 PP == domain 23 score: 29.3 bits; conditional E-value: 8.1e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay+ lg++++A+ey ek Le+ FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIEYHEKHLEI 901 8*************************98 PP == domain 24 score: 21.2 bits; conditional E-value: 2.9e-07 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ lGnay++lg++ +A+ey ek FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHEK 937 899******************998 PP == domain 25 score: 30.7 bits; conditional E-value: 2.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++ +A+ey ek Le+ FUN_002339-T1 954 AYGNLGNAYQSLGDFRKAIEYHEKHLEIA 982 9**************************96 PP == domain 26 score: 28.4 bits; conditional E-value: 1.6e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGna+++lg++ +A+ey ek Le+ FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIEYHEKSLEI 1021 8**************************8 PP == domain 27 score: 26.4 bits; conditional E-value: 6.5e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002339-T1 1033 NAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 1062 59**************************96 PP == domain 28 score: 26.9 bits; conditional E-value: 4.8e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlG ay+++g++ +A+ey ek L++ FUN_002339-T1 1074 AYGNLGIAYQSMGEFRKAIEYHEKHLQI 1101 9*************************98 PP == domain 29 score: 6.8 bits; conditional E-value: 0.011 TPR_1 4 lynlGnayfklgkydeAleyyekA 27 + n+Gn +f+lg+++ Al+ + A FUN_002339-T1 1115 HHNIGNGFFSLGQFEIALDKFVSA 1138 78***************9866555 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.2 0.1 0.018 15 5 33 .. 35 63 .. 35 65 .. 0.90 2 ! 15.9 0.0 1.6e-05 0.014 4 35 .. 74 105 .. 72 108 .. 0.94 3 ! 21.1 0.0 3.8e-07 0.00032 3 35 .. 113 145 .. 112 148 .. 0.95 4 ! 17.8 0.0 4.2e-06 0.0035 3 34 .. 153 184 .. 152 185 .. 0.90 5 ! 13.3 0.0 0.00011 0.092 3 35 .. 193 225 .. 192 225 .. 0.92 6 ! 18.0 0.0 3.5e-06 0.003 4 35 .. 234 265 .. 232 265 .. 0.91 7 ! 11.6 0.0 0.00036 0.31 4 34 .. 274 304 .. 272 305 .. 0.86 8 ! 17.2 0.0 6.2e-06 0.0053 4 34 .. 314 344 .. 312 345 .. 0.90 9 ! 13.3 0.0 0.00011 0.092 3 35 .. 353 385 .. 352 385 .. 0.92 10 ! 18.0 0.0 3.5e-06 0.003 4 35 .. 394 425 .. 392 425 .. 0.91 11 ! 11.6 0.0 0.00036 0.31 4 34 .. 434 464 .. 432 465 .. 0.86 12 ! 18.0 0.0 3.5e-06 0.003 4 35 .. 474 505 .. 472 505 .. 0.91 13 ! 13.4 0.0 9.5e-05 0.081 4 35 .. 514 545 .. 512 545 .. 0.93 14 ! 21.1 0.0 3.8e-07 0.00032 3 35 .. 553 585 .. 552 588 .. 0.95 15 ! 17.8 0.0 4.2e-06 0.0035 3 34 .. 593 624 .. 592 625 .. 0.90 16 ! 13.4 0.0 9.8e-05 0.083 3 35 .. 633 665 .. 632 665 .. 0.92 17 ! 18.0 0.0 3.5e-06 0.003 4 35 .. 674 705 .. 672 705 .. 0.91 18 ! 11.1 0.0 0.00051 0.43 4 34 .. 714 744 .. 712 745 .. 0.89 19 ! 18.0 0.0 3.5e-06 0.003 4 35 .. 754 785 .. 752 785 .. 0.91 20 ! 14.1 0.0 5.9e-05 0.05 4 35 .. 794 825 .. 792 828 .. 0.93 21 ! 21.1 0.0 3.8e-07 0.00032 3 35 .. 833 865 .. 832 868 .. 0.95 22 ! 17.8 0.0 4e-06 0.0034 4 35 .. 874 905 .. 873 905 .. 0.92 23 ! 17.6 0.0 4.7e-06 0.004 4 35 .. 914 945 .. 913 947 .. 0.94 24 ! 20.8 0.0 4.6e-07 0.00039 3 35 .. 953 985 .. 952 986 .. 0.95 25 ! 15.9 0.0 1.5e-05 0.013 4 35 .. 994 1025 .. 993 1028 .. 0.94 26 ! 14.1 0.0 5.9e-05 0.05 4 35 .. 1034 1065 .. 1032 1068 .. 0.93 27 ! 16.9 0.0 7.9e-06 0.0068 3 34 .. 1073 1104 .. 1072 1105 .. 0.91 28 ? -1.7 0.0 5.5 4.7e+03 6 22 .. 1116 1132 .. 1115 1133 .. 0.92 Alignments for each domain: == domain 1 score: 6.2 bits; conditional E-value: 0.018 TPR_10 5 lnnLanalraqgryeeAeelleealaire 33 + nLa a ++ g++ A +++e+ l+i+ FUN_002339-T1 35 YQNLAYAFQSHGDFRKAIKYHEKHLEIAI 63 67********************9888876 PP == domain 2 score: 15.9 bits; conditional E-value: 1.6e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na +++g++ A e++e+ l+i+++v FUN_002339-T1 74 AYGNLGNAFQSLGDFRKAIEYHEKHLEIAKEV 105 899**************************998 PP == domain 3 score: 21.1 bits; conditional E-value: 3.8e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A e++e+ l+i+++v FUN_002339-T1 113 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 145 79****************************998 PP == domain 4 score: 17.8 bits; conditional E-value: 4.2e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+na++++g++ A e++e+ l+i+ + FUN_002339-T1 153 SAYGNLGNAYQSLGDFRKAIEYHEKHLKIAIE 184 79**********************98888766 PP == domain 5 score: 13.3 bits; conditional E-value: 0.00011 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+++++++g++ A e++e+ l+i+ +v FUN_002339-T1 193 SAYGSLGTVYQSLGDFRKAIEYHEKHLEIAIEV 225 6899*********************99998765 PP == domain 6 score: 18.0 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+r++g++ A e++e+ l+i+ +v FUN_002339-T1 234 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 265 899*********************99998765 PP == domain 7 score: 11.6 bits; conditional E-value: 0.00036 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+ ++g++ A e++e+ l+i+ + FUN_002339-T1 274 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAIE 304 7889999999999999999999998888766 PP == domain 8 score: 17.2 bits; conditional E-value: 6.2e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na+r++g++ A e++e+ l+i+ + FUN_002339-T1 314 AYGNLGNAYRSLGDFRKAIEYHEKHLKIAIE 344 899********************98888766 PP == domain 9 score: 13.3 bits; conditional E-value: 0.00011 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+++++++g++ A e++e+ l+i+ +v FUN_002339-T1 353 SAYGSLGTVYQSLGDFRKAIEYHEKHLEIAIEV 385 6899*********************99998765 PP == domain 10 score: 18.0 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+r++g++ A e++e+ l+i+ +v FUN_002339-T1 394 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 425 899*********************99998765 PP == domain 11 score: 11.6 bits; conditional E-value: 0.00036 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+ ++g++ A e++e+ l+i+ + FUN_002339-T1 434 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAIE 464 7889999999999999999999998888766 PP == domain 12 score: 18.0 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+r++g++ A e++e+ l+i+ +v FUN_002339-T1 474 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 505 899*********************99998765 PP == domain 13 score: 13.4 bits; conditional E-value: 9.5e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+ ++g++ A e++e+ l+i+++v FUN_002339-T1 514 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKV 545 7999***********************99987 PP == domain 14 score: 21.1 bits; conditional E-value: 3.8e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A e++e+ l+i+++v FUN_002339-T1 553 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 585 79****************************998 PP == domain 15 score: 17.8 bits; conditional E-value: 4.2e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+na++++g++ A e++e+ l+i+ + FUN_002339-T1 593 SAYGNLGNAYQSLGDFRKAIEYHEKHLKIAIE 624 79**********************98888766 PP == domain 16 score: 13.4 bits; conditional E-value: 9.8e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L++++r++g++ A e++e+ l+i+ +v FUN_002339-T1 633 SAYGSLGTVYRSLGDFRKAIEYHEKHLEIAIEV 665 6899*********************99998765 PP == domain 17 score: 18.0 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+r++g++ A e++e+ l+i+ +v FUN_002339-T1 674 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 705 899*********************99998765 PP == domain 18 score: 11.1 bits; conditional E-value: 0.00051 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+ ++g++ A e++e+ l+i+ + FUN_002339-T1 714 AYGSLGNAYDSLGDFRKAIEYHEKQLEIAIE 744 7999*******************98888766 PP == domain 19 score: 18.0 bits; conditional E-value: 3.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+r++g++ A e++e+ l+i+ +v FUN_002339-T1 754 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 785 899*********************99998765 PP == domain 20 score: 14.1 bits; conditional E-value: 5.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+ ++g++ A e++e+ l+i+++v FUN_002339-T1 794 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKV 825 7999************************9998 PP == domain 21 score: 21.1 bits; conditional E-value: 3.8e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A e++e+ l+i+++v FUN_002339-T1 833 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 865 79****************************998 PP == domain 22 score: 17.8 bits; conditional E-value: 4e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++ +g+++ A e++e+ l+i+ +v FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIEYHEKHLEIAIEV 905 799*********************99998765 PP == domain 23 score: 17.6 bits; conditional E-value: 4.7e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+r++g++ A e++e+ l+i+ +v FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHEKDLEIAIEV 945 7899************************9887 PP == domain 24 score: 20.8 bits; conditional E-value: 4.6e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A e++e+ l+i+++v FUN_002339-T1 953 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 985 79***************************9997 PP == domain 25 score: 15.9 bits; conditional E-value: 1.5e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na +++g++ A e++e++l+i+ +v FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIEYHEKSLEIAIEV 1025 799*************************9887 PP == domain 26 score: 14.1 bits; conditional E-value: 5.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na+ ++g++ A e++e+ l+i+++v FUN_002339-T1 1034 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKV 1065 7999************************9998 PP == domain 27 score: 16.9 bits; conditional E-value: 7.9e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+ a++++g++ A e++e+ l+i+ + FUN_002339-T1 1073 SAYGNLGIAYQSMGEFRKAIEYHEKHLQIAIE 1104 79***********************9988765 PP == domain 28 score: -1.7 bits; conditional E-value: 5.5 TPR_10 6 nnLanalraqgryeeAe 22 +n++n +++g++e A+ FUN_002339-T1 1116 HNIGNGFFSLGQFEIAL 1132 7999*9********997 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.5 0.3 0.009 7.7 3 30 .. 34 61 .. 32 62 .. 0.89 2 ! 16.4 0.1 1.2e-05 0.011 3 32 .. 74 103 .. 72 104 .. 0.91 3 ! 20.4 0.2 6.1e-07 0.00052 2 32 .. 113 143 .. 112 144 .. 0.92 4 ! 19.1 0.2 1.7e-06 0.0014 2 30 .. 153 181 .. 152 182 .. 0.89 5 ! 14.8 0.0 3.9e-05 0.033 2 30 .. 193 221 .. 192 222 .. 0.90 6 ! 19.4 0.2 1.4e-06 0.0012 3 30 .. 234 261 .. 232 262 .. 0.90 7 ! 16.5 0.1 1.2e-05 0.0099 3 30 .. 274 301 .. 272 302 .. 0.90 8 ! 19.0 0.2 1.8e-06 0.0015 3 30 .. 314 341 .. 312 342 .. 0.89 9 ! 14.8 0.0 3.9e-05 0.033 2 30 .. 353 381 .. 352 382 .. 0.90 10 ! 19.4 0.2 1.4e-06 0.0012 3 30 .. 394 421 .. 392 422 .. 0.90 11 ! 16.5 0.1 1.2e-05 0.0099 3 30 .. 434 461 .. 432 462 .. 0.90 12 ! 19.4 0.2 1.4e-06 0.0012 3 30 .. 474 501 .. 472 502 .. 0.90 13 ! 17.9 0.1 4.2e-06 0.0035 3 32 .. 514 543 .. 512 545 .. 0.92 14 ! 20.4 0.2 6.1e-07 0.00052 2 32 .. 553 583 .. 552 584 .. 0.92 15 ! 19.1 0.2 1.7e-06 0.0014 2 30 .. 593 621 .. 592 622 .. 0.89 16 ! 14.9 0.0 3.6e-05 0.031 2 30 .. 633 661 .. 632 662 .. 0.90 17 ! 19.4 0.2 1.4e-06 0.0012 3 30 .. 674 701 .. 672 702 .. 0.90 18 ! 18.9 0.2 1.9e-06 0.0016 3 30 .. 714 741 .. 712 742 .. 0.94 19 ! 19.4 0.2 1.4e-06 0.0012 3 30 .. 754 781 .. 752 782 .. 0.90 20 ! 17.9 0.1 4.2e-06 0.0035 3 32 .. 794 823 .. 792 825 .. 0.92 21 ! 20.4 0.2 6.1e-07 0.00052 2 32 .. 833 863 .. 832 864 .. 0.92 22 ! 19.9 0.2 9e-07 0.00077 3 30 .. 874 901 .. 872 902 .. 0.91 23 ! 15.5 0.1 2.4e-05 0.021 3 26 .. 914 937 .. 912 942 .. 0.89 24 ! 20.4 0.2 6.1e-07 0.00052 2 32 .. 953 983 .. 952 984 .. 0.92 25 ! 19.6 0.1 1.2e-06 0.001 3 31 .. 994 1022 .. 992 1022 .. 0.95 26 ! 17.9 0.1 4.2e-06 0.0035 3 32 .. 1034 1063 .. 1032 1065 .. 0.92 27 ! 13.1 0.2 0.00014 0.12 2 26 .. 1073 1097 .. 1072 1102 .. 0.88 Alignments for each domain: == domain 1 score: 7.5 bits; conditional E-value: 0.009 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 y+nl+++ ++ gd+ +A++y ek le+ FUN_002339-T1 34 GYQNLAYAFQSHGDFRKAIKYHEKHLEI 61 69*******************9987776 PP == domain 2 score: 16.4 bits; conditional E-value: 1.2e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG++ ++lgd+ +A+ey ek le+++ FUN_002339-T1 74 AYGNLGNAFQSLGDFRKAIEYHEKHLEIAK 103 9********************999998875 PP == domain 3 score: 20.4 bits; conditional E-value: 6.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002339-T1 113 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 143 59********************999998875 PP == domain 4 score: 19.1 bits; conditional E-value: 1.7e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd+ +A+ey ek l++ FUN_002339-T1 153 SAYGNLGNAYQSLGDFRKAIEYHEKHLKI 181 59********************8886665 PP == domain 5 score: 14.8 bits; conditional E-value: 3.9e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG +y++lgd+ +A+ey ek le+ FUN_002339-T1 193 SAYGSLGTVYQSLGDFRKAIEYHEKHLEI 221 589*******************9987776 PP == domain 6 score: 19.4 bits; conditional E-value: 1.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002339-T1 234 AYGNLGNAYRSLGDFRKAIEYHEKHLEI 261 9********************9987776 PP == domain 7 score: 16.5 bits; conditional E-value: 1.2e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y +lgd+ +A+ey ek le+ FUN_002339-T1 274 AYGSLGNAYDSLGDFRKAIEYHEKHLEI 301 89*******************9987776 PP == domain 8 score: 19.0 bits; conditional E-value: 1.8e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek l++ FUN_002339-T1 314 AYGNLGNAYRSLGDFRKAIEYHEKHLKI 341 9********************8886665 PP == domain 9 score: 14.8 bits; conditional E-value: 3.9e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG +y++lgd+ +A+ey ek le+ FUN_002339-T1 353 SAYGSLGTVYQSLGDFRKAIEYHEKHLEI 381 589*******************9987776 PP == domain 10 score: 19.4 bits; conditional E-value: 1.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002339-T1 394 AYGNLGNAYRSLGDFRKAIEYHEKHLEI 421 9********************9987776 PP == domain 11 score: 16.5 bits; conditional E-value: 1.2e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y +lgd+ +A+ey ek le+ FUN_002339-T1 434 AYGSLGNAYDSLGDFRKAIEYHEKHLEI 461 89*******************9987776 PP == domain 12 score: 19.4 bits; conditional E-value: 1.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002339-T1 474 AYGNLGNAYRSLGDFRKAIEYHEKHLEI 501 9********************9987776 PP == domain 13 score: 17.9 bits; conditional E-value: 4.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y +lgd+ +A+ey ek le+++ FUN_002339-T1 514 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAK 543 89*******************999999886 PP == domain 14 score: 20.4 bits; conditional E-value: 6.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002339-T1 553 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 583 59********************999998875 PP == domain 15 score: 19.1 bits; conditional E-value: 1.7e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++lgd+ +A+ey ek l++ FUN_002339-T1 593 SAYGNLGNAYQSLGDFRKAIEYHEKHLKI 621 59********************8886665 PP == domain 16 score: 14.9 bits; conditional E-value: 3.6e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG +y++lgd+ +A+ey ek le+ FUN_002339-T1 633 SAYGSLGTVYRSLGDFRKAIEYHEKHLEI 661 589*******************9987776 PP == domain 17 score: 19.4 bits; conditional E-value: 1.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002339-T1 674 AYGNLGNAYRSLGDFRKAIEYHEKHLEI 701 9********************9987776 PP == domain 18 score: 18.9 bits; conditional E-value: 1.9e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y +lgd+ +A+ey ek le+ FUN_002339-T1 714 AYGSLGNAYDSLGDFRKAIEYHEKQLEI 741 89**********************9998 PP == domain 19 score: 19.4 bits; conditional E-value: 1.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002339-T1 754 AYGNLGNAYRSLGDFRKAIEYHEKHLEI 781 9********************9987776 PP == domain 20 score: 17.9 bits; conditional E-value: 4.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y +lgd+ +A+ey ek le+++ FUN_002339-T1 794 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAK 823 89*******************999999886 PP == domain 21 score: 20.4 bits; conditional E-value: 6.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002339-T1 833 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 863 59********************999998875 PP == domain 22 score: 19.9 bits; conditional E-value: 9e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+++A+ey ek le+ FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIEYHEKHLEI 901 8********************9987776 PP == domain 23 score: 15.5 bits; conditional E-value: 2.4e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 ay lG++y++lgd+ +A+ey ek FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHEK 937 899******************777 PP == domain 24 score: 20.4 bits; conditional E-value: 6.1e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002339-T1 953 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 983 59********************999998875 PP == domain 25 score: 19.6 bits; conditional E-value: 1.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay nlG+++++lgd+ +A+ey ek+le++ FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIEYHEKSLEIA 1022 8*************************995 PP == domain 26 score: 17.9 bits; conditional E-value: 4.2e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y +lgd+ +A+ey ek le+++ FUN_002339-T1 1034 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAK 1063 89*******************999999886 PP == domain 27 score: 13.1 bits; conditional E-value: 0.00014 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay nlG +y+++g++ +A+ey ek FUN_002339-T1 1073 SAYGNLGIAYQSMGEFRKAIEYHEK 1097 59********************777 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 9.5 8.1e+03 23 31 .. 7 15 .. 5 18 .. 0.65 2 ? 6.7 0.4 0.015 13 3 23 .. 34 54 .. 32 62 .. 0.91 3 ! 11.0 0.2 0.00063 0.53 3 23 .. 74 94 .. 72 104 .. 0.88 4 ! 14.3 0.3 5.8e-05 0.049 3 23 .. 114 134 .. 112 144 .. 0.89 5 ! 14.1 0.2 6.7e-05 0.057 3 23 .. 154 174 .. 152 181 .. 0.93 6 ! 8.0 0.0 0.0058 4.9 3 23 .. 194 214 .. 192 221 .. 0.91 7 ! 14.8 0.2 3.8e-05 0.032 3 23 .. 234 254 .. 232 261 .. 0.93 8 ! 10.5 0.1 0.00093 0.79 3 23 .. 274 294 .. 272 301 .. 0.91 9 ! 14.9 0.2 3.7e-05 0.032 3 23 .. 314 334 .. 312 341 .. 0.93 10 ! 8.0 0.0 0.0058 4.9 3 23 .. 354 374 .. 352 381 .. 0.91 11 ! 14.8 0.2 3.8e-05 0.032 3 23 .. 394 414 .. 392 421 .. 0.93 12 ! 10.5 0.1 0.00093 0.79 3 23 .. 434 454 .. 432 461 .. 0.91 13 ! 14.8 0.2 3.8e-05 0.032 3 23 .. 474 494 .. 472 501 .. 0.93 14 ! 10.7 0.2 0.00078 0.67 3 23 .. 514 534 .. 512 544 .. 0.87 15 ! 14.3 0.3 5.8e-05 0.049 3 23 .. 554 574 .. 552 584 .. 0.89 16 ! 14.1 0.2 6.7e-05 0.057 3 23 .. 594 614 .. 592 621 .. 0.93 17 ! 8.6 0.0 0.0037 3.2 3 23 .. 634 654 .. 632 661 .. 0.91 18 ! 14.8 0.2 3.8e-05 0.032 3 23 .. 674 694 .. 672 701 .. 0.93 19 ! 10.5 0.1 0.00096 0.82 3 23 .. 714 734 .. 712 741 .. 0.91 20 ! 14.8 0.2 3.8e-05 0.032 3 23 .. 754 774 .. 752 781 .. 0.93 21 ! 10.7 0.2 0.00078 0.67 3 23 .. 794 814 .. 792 824 .. 0.87 22 ! 14.3 0.3 5.8e-05 0.049 3 23 .. 834 854 .. 832 864 .. 0.89 23 ! 14.8 0.2 3.9e-05 0.034 3 23 .. 874 894 .. 872 901 .. 0.93 24 ! 12.5 0.1 0.0002 0.17 3 28 .. 914 939 .. 913 943 .. 0.83 25 ! 14.3 0.3 5.8e-05 0.049 3 23 .. 954 974 .. 952 984 .. 0.89 26 ! 15.6 0.1 2.2e-05 0.019 3 31 .. 994 1022 .. 992 1024 .. 0.93 27 ! 10.7 0.2 0.00078 0.67 3 23 .. 1034 1054 .. 1032 1064 .. 0.87 28 ! 10.7 0.2 0.0008 0.68 3 23 .. 1074 1094 .. 1072 1102 .. 0.92 29 ? 6.6 0.0 0.017 14 4 29 .. 1115 1140 .. 1113 1144 .. 0.90 30 ? -1.0 0.0 4.4 3.8e+03 10 26 .. 1173 1189 .. 1172 1192 .. 0.84 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 9.5 TPR_2 23 ayekAleld 31 +++kA+e+ FUN_002339-T1 7 CFRKAIEYH 15 677777765 PP == domain 2 score: 6.7 bits; conditional E-value: 0.015 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nl++a gd+ +A+++ FUN_002339-T1 34 GYQNLAYAFQSHGDFRKAIKY 54 799****************98 PP == domain 3 score: 11.0 bits; conditional E-value: 0.00063 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+a lgd+ +A+e+ FUN_002339-T1 74 AYGNLGNAFQSLGDFRKAIEY 94 899****************98 PP == domain 4 score: 14.3 bits; conditional E-value: 5.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002339-T1 114 AYGNLGNAYQSLGDFRKAIEY 134 899*****************9 PP == domain 5 score: 14.1 bits; conditional E-value: 6.7e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002339-T1 154 AYGNLGNAYQSLGDFRKAIEY 174 899****************98 PP == domain 6 score: 8.0 bits; conditional E-value: 0.0058 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG +y lgd+ +A+e+ FUN_002339-T1 194 AYGSLGTVYQSLGDFRKAIEY 214 67789**************98 PP == domain 7 score: 14.8 bits; conditional E-value: 3.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002339-T1 234 AYGNLGNAYRSLGDFRKAIEY 254 899****************98 PP == domain 8 score: 10.5 bits; conditional E-value: 0.00093 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002339-T1 274 AYGSLGNAYDSLGDFRKAIEY 294 7888***************98 PP == domain 9 score: 14.9 bits; conditional E-value: 3.7e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002339-T1 314 AYGNLGNAYRSLGDFRKAIEY 334 899****************98 PP == domain 10 score: 8.0 bits; conditional E-value: 0.0058 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG +y lgd+ +A+e+ FUN_002339-T1 354 AYGSLGTVYQSLGDFRKAIEY 374 67789**************98 PP == domain 11 score: 14.8 bits; conditional E-value: 3.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002339-T1 394 AYGNLGNAYRSLGDFRKAIEY 414 899****************98 PP == domain 12 score: 10.5 bits; conditional E-value: 0.00093 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002339-T1 434 AYGSLGNAYDSLGDFRKAIEY 454 7888***************98 PP == domain 13 score: 14.8 bits; conditional E-value: 3.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002339-T1 474 AYGNLGNAYRSLGDFRKAIEY 494 899****************98 PP == domain 14 score: 10.7 bits; conditional E-value: 0.00078 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002339-T1 514 AYGSLGNAYDSLGDFRKAIEY 534 7888***************98 PP == domain 15 score: 14.3 bits; conditional E-value: 5.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002339-T1 554 AYGNLGNAYQSLGDFRKAIEY 574 899*****************9 PP == domain 16 score: 14.1 bits; conditional E-value: 6.7e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002339-T1 594 AYGNLGNAYQSLGDFRKAIEY 614 899****************98 PP == domain 17 score: 8.6 bits; conditional E-value: 0.0037 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG +y+ lgd+ +A+e+ FUN_002339-T1 634 AYGSLGTVYRSLGDFRKAIEY 654 67789**************98 PP == domain 18 score: 14.8 bits; conditional E-value: 3.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002339-T1 674 AYGNLGNAYRSLGDFRKAIEY 694 899****************98 PP == domain 19 score: 10.5 bits; conditional E-value: 0.00096 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002339-T1 714 AYGSLGNAYDSLGDFRKAIEY 734 7888***************98 PP == domain 20 score: 14.8 bits; conditional E-value: 3.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002339-T1 754 AYGNLGNAYRSLGDFRKAIEY 774 899****************98 PP == domain 21 score: 10.7 bits; conditional E-value: 0.00078 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002339-T1 794 AYGSLGNAYDSLGDFRKAIEY 814 7888***************98 PP == domain 22 score: 14.3 bits; conditional E-value: 5.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002339-T1 834 AYGNLGNAYQSLGDFRKAIEY 854 899*****************9 PP == domain 23 score: 14.8 bits; conditional E-value: 3.9e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+++A+e+ FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIEY 894 799****************98 PP == domain 24 score: 12.5 bits; conditional E-value: 0.0002 TPR_2 3 alynlGlayyklgdyeeAleayekAl 28 a+ lG+ay+ lgd+ +A+e+ ek l FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHEKDL 939 5778****************966655 PP == domain 25 score: 14.3 bits; conditional E-value: 5.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002339-T1 954 AYGNLGNAYQSLGDFRKAIEY 974 899*****************9 PP == domain 26 score: 15.6 bits; conditional E-value: 2.2e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG+a+ lgd+ +A+e+ ek+le++ FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIEYHEKSLEIA 1022 799******************99999985 PP == domain 27 score: 10.7 bits; conditional E-value: 0.00078 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002339-T1 1034 AYGSLGNAYDSLGDFRKAIEY 1054 7888***************98 PP == domain 28 score: 10.7 bits; conditional E-value: 0.0008 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay +g++ +A+e+ FUN_002339-T1 1074 AYGNLGIAYQSMGEFRKAIEY 1094 899****************98 PP == domain 29 score: 6.6 bits; conditional E-value: 0.017 TPR_2 4 lynlGlayyklgdyeeAleayekAle 29 ++n G+ + lg++e Al+ + A+e FUN_002339-T1 1115 HHNIGNGFFSLGQFEIALDKFVSAVE 1140 89******************998887 PP == domain 30 score: -1.0 bits; conditional E-value: 4.4 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002339-T1 1173 SLLRIGKIDEALFAADE 1189 67899*******98776 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 171.1 0.0 5.7e-53 4.9e-50 8 291 .] 1329 1591 .. 1324 1591 .. 0.89 Alignments for each domain: == domain 1 score: 171.1 bits; conditional E-value: 5.7e-53 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ +Lviv d++L +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ ++ k FUN_002339-T1 1329 YDAVIGPIEDLL-GPEDDELVIVSDSELCFIPWAAVIESIR---------IRIVPSLKSyqlISSVPEGYHKKTGA--LLVGNPCTKQ----LK 1406 899****99997.77777*****************988863.........55556654422266666666666666..*******885....47 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 +++lp +++E++++a++l++ ++l++++at+ ++++ + ++++++H+a+Hg + ++L++ n + ed +L++++++ FUN_002339-T1 1407 KPLEPLPCAQKEVEMIAAILNT---RPLIRKQATKAEVMKRM-SSVGLIHIAAHGDEV-----TGQIALSP-NPGwtqfpkeEDYVLKMSDVQA 1490 777*****************88...8***************9.************999.....88899974.4445889999************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002339-T1 1491 ANLR-ARLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATMEFMKRFYRHLKEGKTASAAVHQSMKSLRESEE----FSE 1579 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 ++WA f+liGd FUN_002339-T1 1580 MWDWAPFQLIGD 1591 ***********7 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.13 1.1e+02 4 29 .. 35 60 .. 32 64 .. 0.89 2 ? 4.1 0.0 0.17 1.5e+02 6 31 .. 77 102 .. 73 107 .. 0.85 3 ? 6.0 0.0 0.042 36 6 31 .. 117 142 .. 113 148 .. 0.86 4 ? 5.3 0.0 0.072 61 6 29 .. 157 180 .. 153 182 .. 0.88 5 ? 3.1 0.0 0.36 3.1e+02 6 29 .. 197 220 .. 193 222 .. 0.86 6 ? 7.1 0.0 0.018 16 6 29 .. 237 260 .. 233 262 .. 0.86 7 ? 5.0 0.0 0.085 73 5 29 .. 276 300 .. 273 302 .. 0.86 8 ? 7.2 0.0 0.017 14 6 29 .. 317 340 .. 313 342 .. 0.87 9 ? 3.1 0.0 0.36 3.1e+02 6 29 .. 357 380 .. 353 382 .. 0.86 10 ? 7.1 0.0 0.018 16 6 29 .. 397 420 .. 393 422 .. 0.86 11 ? 5.0 0.0 0.085 73 5 29 .. 436 460 .. 433 462 .. 0.86 12 ? 7.1 0.0 0.018 16 6 29 .. 477 500 .. 473 502 .. 0.86 13 ? 5.8 0.0 0.049 42 5 30 .. 516 541 .. 513 547 .. 0.86 14 ? 6.0 0.0 0.042 36 6 31 .. 557 582 .. 553 588 .. 0.86 15 ? 5.3 0.0 0.072 61 6 29 .. 597 620 .. 593 622 .. 0.88 16 ? 4.8 0.0 0.1 87 6 29 .. 637 660 .. 633 662 .. 0.86 17 ? 7.1 0.0 0.018 16 6 29 .. 677 700 .. 673 702 .. 0.86 18 ? 4.5 0.0 0.12 1e+02 5 29 .. 716 740 .. 713 742 .. 0.85 19 ? 7.1 0.0 0.018 16 6 29 .. 757 780 .. 753 782 .. 0.86 20 ? 5.8 0.0 0.048 41 5 30 .. 796 821 .. 793 827 .. 0.85 21 ? 6.0 0.0 0.043 37 6 31 .. 837 862 .. 833 867 .. 0.86 22 ? 6.0 0.0 0.042 36 6 29 .. 877 900 .. 873 902 .. 0.87 23 ? 5.1 0.0 0.084 71 6 25 .. 917 936 .. 913 937 .. 0.86 24 ? 6.0 0.0 0.041 35 6 31 .. 957 982 .. 953 988 .. 0.86 25 ? 4.0 0.0 0.18 1.6e+02 7 29 .. 998 1020 .. 993 1023 .. 0.88 26 ? 5.8 0.0 0.048 41 5 30 .. 1036 1061 .. 1033 1067 .. 0.85 27 ? 1.6 0.0 1.1 9.7e+02 7 29 .. 1078 1100 .. 1073 1102 .. 0.86 28 ? -1.2 0.0 9.1 7.8e+03 7 25 .. 1125 1143 .. 1119 1154 .. 0.59 29 ? 3.0 0.1 0.39 3.3e+02 10 41 .. 1173 1205 .. 1171 1207 .. 0.75 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.13 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ la+a+ Gd+ +A+++ e+ l+ FUN_002339-T1 35 YQNLAYAFQSHGDFRKAIKYHEKHLE 60 7889****************999876 PP == domain 2 score: 4.1 bits; conditional E-value: 0.17 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 77 NLGNAFQSLGDFRKAIEYHEKHLEIA 102 68999*************99998865 PP == domain 3 score: 6.0 bits; conditional E-value: 0.042 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 117 NLGNAYQSLGDFRKAIEYHEKHLEIA 142 5899***************9998865 PP == domain 4 score: 5.3 bits; conditional E-value: 0.072 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 157 NLGNAYQSLGDFRKAIEYHEKHLK 180 5899**************999876 PP == domain 5 score: 3.1 bits; conditional E-value: 0.36 TPR_14 6 alarallalGdpdeAlellerala 29 l+ ++ lGd+ +A+e+ e+ l+ FUN_002339-T1 197 SLGTVYQSLGDFRKAIEYHEKHLE 220 58899*************998876 PP == domain 6 score: 7.1 bits; conditional E-value: 0.018 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002339-T1 237 NLGNAYRSLGDFRKAIEYHEKHLE 260 699***************998876 PP == domain 7 score: 5.0 bits; conditional E-value: 0.085 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 276 GSLGNAYDSLGDFRKAIEYHEKHLE 300 5799***************998876 PP == domain 8 score: 7.2 bits; conditional E-value: 0.017 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002339-T1 317 NLGNAYRSLGDFRKAIEYHEKHLK 340 699***************999876 PP == domain 9 score: 3.1 bits; conditional E-value: 0.36 TPR_14 6 alarallalGdpdeAlellerala 29 l+ ++ lGd+ +A+e+ e+ l+ FUN_002339-T1 357 SLGTVYQSLGDFRKAIEYHEKHLE 380 58899*************998876 PP == domain 10 score: 7.1 bits; conditional E-value: 0.018 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002339-T1 397 NLGNAYRSLGDFRKAIEYHEKHLE 420 699***************998876 PP == domain 11 score: 5.0 bits; conditional E-value: 0.085 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 436 GSLGNAYDSLGDFRKAIEYHEKHLE 460 5799***************998876 PP == domain 12 score: 7.1 bits; conditional E-value: 0.018 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002339-T1 477 NLGNAYRSLGDFRKAIEYHEKHLE 500 699***************998876 PP == domain 13 score: 5.8 bits; conditional E-value: 0.049 TPR_14 5 lalarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 516 GSLGNAYDSLGDFRKAIEYHEKHLEI 541 5799***************9999886 PP == domain 14 score: 6.0 bits; conditional E-value: 0.042 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 557 NLGNAYQSLGDFRKAIEYHEKHLEIA 582 5899***************9998865 PP == domain 15 score: 5.3 bits; conditional E-value: 0.072 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 597 NLGNAYQSLGDFRKAIEYHEKHLK 620 5899**************999876 PP == domain 16 score: 4.8 bits; conditional E-value: 0.1 TPR_14 6 alarallalGdpdeAlellerala 29 l+ +++ lGd+ +A+e+ e+ l+ FUN_002339-T1 637 SLGTVYRSLGDFRKAIEYHEKHLE 660 58899*************998876 PP == domain 17 score: 7.1 bits; conditional E-value: 0.018 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002339-T1 677 NLGNAYRSLGDFRKAIEYHEKHLE 700 699***************998876 PP == domain 18 score: 4.5 bits; conditional E-value: 0.12 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 716 GSLGNAYDSLGDFRKAIEYHEKQLE 740 5799**************9998765 PP == domain 19 score: 7.1 bits; conditional E-value: 0.018 TPR_14 6 alarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e+ l+ FUN_002339-T1 757 NLGNAYRSLGDFRKAIEYHEKHLE 780 699***************998876 PP == domain 20 score: 5.8 bits; conditional E-value: 0.048 TPR_14 5 lalarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 796 GSLGNAYDSLGDFRKAIEYHEKHLEI 821 5799***************9999886 PP == domain 21 score: 6.0 bits; conditional E-value: 0.043 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 837 NLGNAYQSLGDFRKAIEYHEKHLEIA 862 5899**************99998865 PP == domain 22 score: 6.0 bits; conditional E-value: 0.042 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+++A+e+ e+ l+ FUN_002339-T1 877 NLGNAYQTLGDFQKAIEYHEKHLE 900 589***************998876 PP == domain 23 score: 5.1 bits; conditional E-value: 0.084 TPR_14 6 alarallalGdpdeAlelle 25 l++a++ lGd+ +A+e+ e FUN_002339-T1 917 SLGNAYRSLGDFRKAIEYHE 936 699*************9866 PP == domain 24 score: 6.0 bits; conditional E-value: 0.041 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 957 NLGNAYQSLGDFRKAIEYHEKHLEIA 982 5899***************9998865 PP == domain 25 score: 4.0 bits; conditional E-value: 0.18 TPR_14 7 larallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 998 LGNACQSLGDFRKAIEYHEKSLE 1020 899**************999876 PP == domain 26 score: 5.8 bits; conditional E-value: 0.048 TPR_14 5 lalarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e+ l+ FUN_002339-T1 1036 GSLGNAYDSLGDFRKAIEYHEKHLEI 1061 5799***************9999886 PP == domain 27 score: 1.6 bits; conditional E-value: 1.1 TPR_14 7 larallalGdpdeAlellerala 29 l+ a+ G++ +A+e+ e+ l+ FUN_002339-T1 1078 LGIAYQSMGEFRKAIEYHEKHLQ 1100 78899************998776 PP == domain 28 score: -1.2 bits; conditional E-value: 9.1 TPR_14 7 larallalGdpdeAlelle 25 l++++ al+++ A+e+++ FUN_002339-T1 1125 LGQFEIALDKFVSAVEAFN 1143 4455555555555555544 PP == domain 29 score: 3.0 bits; conditional E-value: 0.39 TPR_14 10 allalGdpdeAlelleralal.dPddpeawlal 41 ll+ G+ deAl +++++ a+ d+ +++++l FUN_002339-T1 1173 SLLRIGKIDEALFAADEGRAQtLSDNLWIQYKL 1205 6899**************776234555555555 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.1 0.3 2.5e+02 15 33 .. 34 52 .. 32 53 .. 0.91 2 ? 4.3 0.0 0.097 83 14 34 .] 73 93 .. 71 93 .. 0.92 3 ? 7.4 0.1 0.01 8.5 14 34 .] 113 133 .. 111 133 .. 0.92 4 ? 7.3 0.1 0.011 9.3 15 34 .] 154 173 .. 152 173 .. 0.92 5 ? 3.4 0.0 0.2 1.7e+02 15 34 .] 194 213 .. 191 213 .. 0.91 6 ! 8.0 0.1 0.0064 5.5 14 34 .] 233 253 .. 231 253 .. 0.93 7 ? 4.5 0.0 0.084 72 14 34 .] 273 293 .. 271 293 .. 0.92 8 ! 8.0 0.1 0.0064 5.5 14 34 .] 313 333 .. 311 333 .. 0.93 9 ? 3.4 0.0 0.2 1.7e+02 15 34 .] 354 373 .. 351 373 .. 0.91 10 ! 8.0 0.1 0.0064 5.5 14 34 .] 393 413 .. 391 413 .. 0.93 11 ? 4.5 0.0 0.084 72 14 34 .] 433 453 .. 431 453 .. 0.92 12 ! 8.0 0.1 0.0064 5.5 14 34 .] 473 493 .. 471 493 .. 0.93 13 ? 4.5 0.0 0.084 72 14 34 .] 513 533 .. 511 533 .. 0.92 14 ? 7.4 0.1 0.01 8.5 14 34 .] 553 573 .. 551 573 .. 0.92 15 ? 7.3 0.1 0.011 9.3 15 34 .] 594 613 .. 592 613 .. 0.92 16 ? 3.4 0.0 0.2 1.7e+02 15 34 .] 634 653 .. 631 653 .. 0.91 17 ! 8.0 0.1 0.0064 5.5 14 34 .] 673 693 .. 671 693 .. 0.93 18 ? 4.5 0.0 0.084 72 14 34 .] 713 733 .. 711 733 .. 0.92 19 ! 8.0 0.1 0.0064 5.5 14 34 .] 753 773 .. 751 773 .. 0.93 20 ? 4.5 0.0 0.084 72 14 34 .] 793 813 .. 791 813 .. 0.92 21 ? 7.4 0.1 0.01 8.5 14 34 .] 833 853 .. 831 853 .. 0.92 22 ! 7.7 0.1 0.0081 6.9 15 34 .] 874 893 .. 872 893 .. 0.93 23 ? 4.1 0.0 0.12 1e+02 15 34 .] 914 933 .. 912 933 .. 0.92 24 ? 7.4 0.1 0.01 8.5 14 34 .] 953 973 .. 951 973 .. 0.92 25 ? 3.4 0.0 0.2 1.7e+02 15 34 .] 994 1013 .. 992 1013 .. 0.93 26 ? 4.5 0.0 0.084 72 14 34 .] 1033 1053 .. 1031 1053 .. 0.92 27 ? 5.7 0.0 0.036 31 14 34 .] 1073 1093 .. 1071 1093 .. 0.92 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.3 TPR_17 15 ayynLArlllnnGqleeAl 33 y+nLA++ + G++ +A+ FUN_002339-T1 34 GYQNLAYAFQSHGDFRKAI 52 69**************998 PP == domain 2 score: 4.3 bits; conditional E-value: 0.097 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++ + +G++ +A++ FUN_002339-T1 73 NAYGNLGNAFQSLGDFRKAIE 93 79****************985 PP == domain 3 score: 7.4 bits; conditional E-value: 0.01 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 113 SAYGNLGNAYQSLGDFRKAIE 133 59****************985 PP == domain 4 score: 7.3 bits; conditional E-value: 0.011 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 154 AYGNLGNAYQSLGDFRKAIE 173 8****************985 PP == domain 5 score: 3.4 bits; conditional E-value: 0.2 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002339-T1 194 AYGSLGTVYQSLGDFRKAIE 213 899**************985 PP == domain 6 score: 8.0 bits; conditional E-value: 0.0064 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002339-T1 233 NAYGNLGNAYRSLGDFRKAIE 253 79****************985 PP == domain 7 score: 4.5 bits; conditional E-value: 0.084 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L++++ +G++ +A++ FUN_002339-T1 273 NAYGSLGNAYDSLGDFRKAIE 293 79****************985 PP == domain 8 score: 8.0 bits; conditional E-value: 0.0064 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002339-T1 313 NAYGNLGNAYRSLGDFRKAIE 333 79****************985 PP == domain 9 score: 3.4 bits; conditional E-value: 0.2 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002339-T1 354 AYGSLGTVYQSLGDFRKAIE 373 899**************985 PP == domain 10 score: 8.0 bits; conditional E-value: 0.0064 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002339-T1 393 NAYGNLGNAYRSLGDFRKAIE 413 79****************985 PP == domain 11 score: 4.5 bits; conditional E-value: 0.084 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L++++ +G++ +A++ FUN_002339-T1 433 NAYGSLGNAYDSLGDFRKAIE 453 79****************985 PP == domain 12 score: 8.0 bits; conditional E-value: 0.0064 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002339-T1 473 NAYGNLGNAYRSLGDFRKAIE 493 79****************985 PP == domain 13 score: 4.5 bits; conditional E-value: 0.084 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L++++ +G++ +A++ FUN_002339-T1 513 NAYGSLGNAYDSLGDFRKAIE 533 79****************985 PP == domain 14 score: 7.4 bits; conditional E-value: 0.01 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 553 SAYGNLGNAYQSLGDFRKAIE 573 59****************985 PP == domain 15 score: 7.3 bits; conditional E-value: 0.011 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 594 AYGNLGNAYQSLGDFRKAIE 613 8****************985 PP == domain 16 score: 3.4 bits; conditional E-value: 0.2 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002339-T1 634 AYGSLGTVYRSLGDFRKAIE 653 899**************985 PP == domain 17 score: 8.0 bits; conditional E-value: 0.0064 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002339-T1 673 NAYGNLGNAYRSLGDFRKAIE 693 79****************985 PP == domain 18 score: 4.5 bits; conditional E-value: 0.084 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L++++ +G++ +A++ FUN_002339-T1 713 NAYGSLGNAYDSLGDFRKAIE 733 79****************985 PP == domain 19 score: 8.0 bits; conditional E-value: 0.0064 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002339-T1 753 NAYGNLGNAYRSLGDFRKAIE 773 79****************985 PP == domain 20 score: 4.5 bits; conditional E-value: 0.084 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L++++ +G++ +A++ FUN_002339-T1 793 NAYGSLGNAYDSLGDFRKAIE 813 79****************985 PP == domain 21 score: 7.4 bits; conditional E-value: 0.01 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 833 SAYGNLGNAYQSLGDFRKAIE 853 59****************985 PP == domain 22 score: 7.7 bits; conditional E-value: 0.0081 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++++A++ FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIE 893 89****************85 PP == domain 23 score: 4.1 bits; conditional E-value: 0.12 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIE 933 899**************985 PP == domain 24 score: 7.4 bits; conditional E-value: 0.01 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 953 SAYGNLGNAYQSLGDFRKAIE 973 59****************985 PP == domain 25 score: 3.4 bits; conditional E-value: 0.2 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++ + +G++ +A++ FUN_002339-T1 994 AYGNLGNACQSLGDFRKAIE 1013 89***************985 PP == domain 26 score: 4.5 bits; conditional E-value: 0.084 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L++++ +G++ +A++ FUN_002339-T1 1033 NAYGSLGNAYDSLGDFRKAIE 1053 79****************985 PP == domain 27 score: 5.7 bits; conditional E-value: 0.036 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002339-T1 1073 SAYGNLGIAYQSMGEFRKAIE 1093 59***************9985 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.1 0.12 1e+02 40 75 .. 32 64 .. 5 68 .. 0.62 2 ! 8.4 0.0 0.0037 3.1 46 78 .. 75 107 .. 65 109 .. 0.89 3 ! 9.0 0.0 0.0023 2 45 78 .. 114 147 .. 106 149 .. 0.87 4 ? 4.7 0.1 0.053 45 47 76 .. 156 185 .. 152 189 .. 0.90 5 ? 4.2 0.0 0.074 63 47 76 .. 196 225 .. 187 229 .. 0.86 6 ? 5.1 0.0 0.039 34 46 76 .. 235 265 .. 226 269 .. 0.88 7 ? 5.0 0.0 0.042 35 46 76 .. 275 305 .. 267 309 .. 0.89 8 ? 4.9 0.0 0.044 38 46 76 .. 315 345 .. 304 349 .. 0.88 9 ? 4.2 0.0 0.074 63 47 76 .. 356 385 .. 347 389 .. 0.86 10 ? 5.1 0.0 0.039 34 46 76 .. 395 425 .. 386 429 .. 0.88 11 ? 5.1 0.0 0.041 35 46 76 .. 435 465 .. 426 468 .. 0.88 12 ? 5.1 0.0 0.04 34 46 76 .. 475 505 .. 466 508 .. 0.88 13 ? 5.5 0.0 0.031 26 46 77 .. 515 546 .. 506 549 .. 0.88 14 ! 10.2 0.0 0.001 0.88 35 78 .. 544 587 .. 542 589 .. 0.87 15 ? 4.6 0.1 0.056 48 47 76 .. 596 625 .. 593 628 .. 0.90 16 ? 3.8 0.0 0.1 88 47 76 .. 636 665 .. 627 669 .. 0.87 17 ? 5.1 0.0 0.04 34 46 76 .. 675 705 .. 666 708 .. 0.88 18 ! 8.4 0.0 0.0036 3 46 76 .. 715 745 .. 707 749 .. 0.89 19 ? 5.2 0.0 0.038 32 46 76 .. 755 785 .. 745 789 .. 0.88 20 ? 5.7 0.0 0.026 22 46 78 .. 795 827 .. 787 828 .. 0.88 21 ! 13.0 0.0 0.00014 0.12 32 78 .. 821 867 .. 818 869 .. 0.93 22 ? 5.5 0.1 0.031 26 37 78 .. 866 907 .. 863 909 .. 0.84 23 ? 6.4 0.0 0.016 14 46 78 .. 915 947 .. 905 949 .. 0.89 24 ! 8.0 0.0 0.0049 4.2 46 76 .. 955 985 .. 945 989 .. 0.88 25 ? 4.7 0.0 0.053 45 47 78 .. 996 1027 .. 986 1029 .. 0.89 26 ! 7.0 0.0 0.0098 8.4 37 78 .. 1026 1067 .. 1024 1069 .. 0.87 27 ! 11.7 0.1 0.00035 0.3 32 77 .. 1061 1106 .. 1058 1108 .. 0.92 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.12 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaee 75 e ++ l y +++h G ++ a+++ + l+ia e FUN_002339-T1 32 EKGYQNLAYAFQSH---GDFRKAIKYHEKHLEIAIE 64 33355556655555...889999*999999999876 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0037 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a +G ++ a+e+ + l+ia+e+ d FUN_002339-T1 75 YGNLGNAFQSLGDFRKAIEYHEKHLEIAKEVSD 107 688999************************976 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0023 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002339-T1 114 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSD 147 5688999************************976 PP == domain 4 score: 4.7 bits; conditional E-value: 0.053 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l ia e+ FUN_002339-T1 156 GNLGNAYQSLGDFRKAIEYHEKHLKIAIEV 185 788899********************9886 PP == domain 5 score: 4.2 bits; conditional E-value: 0.074 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l t + +G ++ a+e+ + l+ia e+ FUN_002339-T1 196 GSLGTVYQSLGDFRKAIEYHEKHLEIAIEV 225 777788889*****************9887 PP == domain 6 score: 5.1 bits; conditional E-value: 0.039 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 235 YGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 265 688999*********************9886 PP == domain 7 score: 5.0 bits; conditional E-value: 0.042 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 275 YGSLGNAYDSLGDFRKAIEYHEKHLEIAIEV 305 5889999********************9887 PP == domain 8 score: 4.9 bits; conditional E-value: 0.044 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l ia e+ FUN_002339-T1 315 YGNLGNAYRSLGDFRKAIEYHEKHLKIAIEV 345 688999*********************9886 PP == domain 9 score: 4.2 bits; conditional E-value: 0.074 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l t + +G ++ a+e+ + l+ia e+ FUN_002339-T1 356 GSLGTVYQSLGDFRKAIEYHEKHLEIAIEV 385 777788889*****************9887 PP == domain 10 score: 5.1 bits; conditional E-value: 0.039 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 395 YGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 425 688999*********************9886 PP == domain 11 score: 5.1 bits; conditional E-value: 0.041 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 435 YGSLGNAYDSLGDFRKAIEYHEKHLEIAIEV 465 688999*********************9886 PP == domain 12 score: 5.1 bits; conditional E-value: 0.04 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 475 YGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 505 688999*********************9886 PP == domain 13 score: 5.5 bits; conditional E-value: 0.031 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l+ia+ + FUN_002339-T1 515 YGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVG 546 688999**********************9875 PP == domain 14 score: 10.2 bits; conditional E-value: 0.001 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 k dr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002339-T1 544 KVGDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSD 587 6667777777889999*************************976 PP == domain 15 score: 4.6 bits; conditional E-value: 0.056 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l ia e+ FUN_002339-T1 596 GNLGNAYQSLGDFRKAIEYHEKHLKIAIEV 625 788899*******************99886 PP == domain 16 score: 3.8 bits; conditional E-value: 0.1 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l t + +G ++ a+e+ + l+ia e+ FUN_002339-T1 636 GSLGTVYRSLGDFRKAIEYHEKHLEIAIEV 665 778888899*****************9887 PP == domain 17 score: 5.1 bits; conditional E-value: 0.04 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 675 YGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 705 688999*********************9886 PP == domain 18 score: 8.4 bits; conditional E-value: 0.0036 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ +ql+ia e+ FUN_002339-T1 715 YGSLGNAYDSLGDFRKAIEYHEKQLEIAIEV 745 588999**********************987 PP == domain 19 score: 5.2 bits; conditional E-value: 0.038 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002339-T1 755 YGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 785 688999*********************9886 PP == domain 20 score: 5.7 bits; conditional E-value: 0.026 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+ + d FUN_002339-T1 795 YGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSD 827 588999**********************98765 PP == domain 21 score: 13.0 bits; conditional E-value: 0.00014 Rapsyn_N 32 vlkktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 + kk sdr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002339-T1 821 IAKKVSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSD 867 569999**9999********************************976 PP == domain 22 score: 5.5 bits; conditional E-value: 0.031 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeeled 78 sdr + G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002339-T1 866 SDRVGEGGAYGNLGNAYQTLGDFQKAIEYHEKHLEIAIEVGD 907 666666667899999**********************99865 PP == domain 23 score: 6.4 bits; conditional E-value: 0.016 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002339-T1 915 YGSLGNAYRSLGDFRKAIEYHEKDLEIAIEVSD 947 588999**********************99876 PP == domain 24 score: 8.0 bits; conditional E-value: 0.0049 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002339-T1 955 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 985 688999***********************98 PP == domain 25 score: 4.7 bits; conditional E-value: 0.053 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeeled 78 G l +a +G ++ a+e+ + l+ia e+ d FUN_002339-T1 996 GNLGNACQSLGDFRKAIEYHEKSLEIAIEVSD 1027 77889999*******************99876 PP == domain 26 score: 7.0 bits; conditional E-value: 0.0098 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeeled 78 sdr + + G l +a+ +G ++ a+e+ + l+ia+ + d FUN_002339-T1 1026 SDRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSD 1067 56667777789999***********************98765 PP == domain 27 score: 11.7 bits; conditional E-value: 0.00035 Rapsyn_N 32 vlkktsdredkfrllGylitahsemGkykealefslaqlniaeele 77 + kk sdr + G l a+ mG ++ a+e+ + l+ia el FUN_002339-T1 1061 IAKKVSDRVGEGSAYGNLGIAYQSMGEFRKAIEYHEKHLQIAIELG 1106 5689999999999*****************************9985 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 2.2e-05 0.018 13 111 .. 84 183 .. 35 189 .. 0.56 2 ! 19.6 0.0 7.6e-07 0.00065 14 152 .. 85 222 .. 78 230 .. 0.86 3 ! 19.3 0.0 8.9e-07 0.00076 13 152 .. 124 262 .. 122 269 .. 0.90 4 ! 13.1 0.0 7.1e-05 0.06 13 152 .. 244 382 .. 238 394 .. 0.84 5 ! 12.8 0.0 8.7e-05 0.074 16 152 .. 287 422 .. 282 432 .. 0.76 6 ! 15.4 0.0 1.4e-05 0.012 13 191 .. 404 582 .. 399 584 .. 0.91 7 ! 19.3 0.0 9.4e-07 0.0008 15 153 .. 526 663 .. 521 674 .. 0.82 8 ! 20.6 0.0 3.7e-07 0.00032 12 154 .. 563 704 .. 558 748 .. 0.87 9 ! 15.6 0.0 1.2e-05 0.01 13 192 .. 684 863 .. 678 866 .. 0.91 10 ! 22.0 0.0 1.4e-07 0.00012 14 192 .. 805 983 .. 799 989 .. 0.86 11 ! 12.4 0.0 0.00011 0.098 15 183 .. 926 1094 .. 924 1104 .. 0.79 12 ! 6.8 0.0 0.0059 5 13 117 .. 1004 1109 .. 999 1140 .. 0.83 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 2.2e-05 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ +e +d + ++a+ +lG a++ +gd+ +A + ++ ++a++ + v a+ +++ ++ G++++A+e ++ l FUN_002339-T1 84 SLGDFRKAIEYHEKHLEIAKEvSDRFGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHL 179 335555555555555555544334444455556666666666666555555555555555555555555555566666666666666666555555 PP TPR_MalT 108 qlaq 111 + a FUN_002339-T1 180 KIAI 183 5554 PP == domain 2 score: 19.6 bits; conditional E-value: 7.6e-07 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ +e +d + ++a+ +lG a++ +gd+ +A + ++ ++a++ + v a+ +++ ++ G++++A+e ++ l+ FUN_002339-T1 85 LGDFRKAIEYHEKHLEIAKEvSDRFGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLK 180 6899999999999999998756667789999************9999999999999999999999999999999********************** PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 a e + + g ++ +l+ ++ +d+ +A ++ ++ ++++ FUN_002339-T1 181 IAIEVGHRV--GEGSAYGSLGTVYQSLGDFRKAIEYHEKHLEIA 222 999998885..778899999999999999999988887777665 PP == domain 3 score: 19.3 bits; conditional E-value: 8.9e-07 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ +e +d + ++a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ +++ G++++A+e ++ l FUN_002339-T1 124 SLGDFRKAIEYHEKHLEIAKEvSDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYQSLGDFRKAIEYHEKHL 219 568999***********99875677889******************99999999999999999999999*************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 + a e + + g ++ l++ ++ +d+ +A ++ ++ ++++ FUN_002339-T1 220 EIAIEVGNRV--GEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEIA 262 *****99995..8899999************99988887776665 PP == domain 4 score: 13.1 bits; conditional E-value: 7.1e-05 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + + a+ +lG a+ +gd+ +A + ++ ++a + ++ a+ +++ +r G++++A+e ++ l FUN_002339-T1 244 SLGDFRKAIEYHEKHLEIAIEVGHRVGeGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 339 668888999999999999888888887799999999999999999999999999999999999999999999999999999999999999999999 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 + a e + + g ++ +l+ ++ +d+ +A ++ ++ ++++ FUN_002339-T1 340 KIAIEVGHRV--GEGSAYGSLGTVYQSLGDFRKAIEYHEKHLEIA 382 9999988885..777888999999999999999987777766665 PP == domain 5 score: 12.8 bits; conditional E-value: 8.7e-05 TPR_MalT 16 eaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 ++ +a+e+ ++ L++ e + + a+ +lG a+ +gd+ +A + ++ ++a + ++ a+ +++ +++ G++++A+e ++ l+ a FUN_002339-T1 287 DFRKAIEYHEKHLEIAIEvGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYQSLGDFRKAIEYHEKHLEIA 382 555666666666655433123333477889999999999999999888888888888888888889999999999999999999999999999999 PP TPR_MalT 111 qesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlg 152 e + + g ++ l++ ++ +d+ +A ++ ++ ++++ FUN_002339-T1 383 IEVGNRV--GEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEIA 422 9999885..778889999999999999999977776665554 PP == domain 6 score: 15.4 bits; conditional E-value: 1.4e-05 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + + a+ +lG a+ +gd+ +A + ++ ++a + ++ a+ +++ +r G++++A+e ++ l FUN_002339-T1 404 SLGDFRKAIEYHEKHLEIAIEVGHRVGeGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 499 678999999999999999999998887799*********************99999999999999999**************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerla 191 + a e + + g ++ +l++ + +d+ +A ++ ++ +++++++ ++ ay l + ++ G+ + A ++ ++ ++a FUN_002339-T1 500 EIAIEVGHRV--GEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVgDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIA 582 ****999885..88999******************************97889999999999999999999999999888877666 PP == domain 7 score: 19.3 bits; conditional E-value: 9.4e-07 TPR_MalT 15 geaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ ++ d+ ++a+ +lG a++ +gd+ +A + ++ ++a++ + v a+ +++ ++ G++++A+e ++ l+ FUN_002339-T1 526 GDFRKAIEYHEKHLEIAKKvgDR-VGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLK 620 77888888888888888763234.334778899999999999999999999999999999999888999999999999999999999999999999 PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgr 153 a e + + g ++ +l+ +++ +d+ +A ++ ++ ++++ FUN_002339-T1 621 IAIEVGHRV--GEGSAYGSLGTVYRSLGDFRKAIEYHEKHLEIAI 663 999998885..7788999999999999999999887777666654 PP == domain 8 score: 20.6 bits; conditional E-value: 3.7e-07 TPR_MalT 12 vsqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 s g++ +a+e+ ++ L++ +e +d + ++a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ ++r G++++A+e ++ FUN_002339-T1 563 QSLGDFRKAIEYHEKHLEIAKEvSDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYRSLGDFRKAIEYHEKH 658 578999*************9875677889******************999999999999999999999999************************* PP TPR_MalT 107 lqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrq 154 l+ a e + + g ++ l++ ++ +d+ +A ++ ++ ++++ + FUN_002339-T1 659 LEIAIEVGNRV--GEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIE 704 *******9995..889999****************8887777766554 PP == domain 9 score: 15.6 bits; conditional E-value: 1.2e-05 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + + a+ +lG a+ +gd+ +A + ++ ++a + ++ a+ +++ +r G++++A+e ++ l FUN_002339-T1 684 SLGDFRKAIEYHEKHLEIAIEVGHRVGeGNAYGSLGNAYDSLGDFRKAIEYHEKQLEIAIEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 779 678999999999999999999998887799********************999999999999999999**************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerlar 192 + a e + + g ++ +l++ + +d+ +A ++ ++ +++++++ ++ ay l + ++ G+ + A ++ ++ ++a+ FUN_002339-T1 780 EIAIEVGHRV--GEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVsDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 863 *****99885..8899*******************************967789999999999999999999999999888777765 PP == domain 10 score: 22.0 bits; conditional E-value: 1.4e-07 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ ++ +d ++a+ +lG a++ +gd+ +A + ++ ++a++ + a+ +++ +++ G++++A+e ++ l+ FUN_002339-T1 805 LGDFRKAIEYHEKHLEIAKKvSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGGAYGNLGNAYQTLGDFQKAIEYHEKHLE 900 6889999999999999998733334458889*************9999999999999999888888999*************************** PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerlar 192 a e + + g+++ +l++ ++ +d+ +A ++ ++ ++++ ++ ++ ay l + ++ G+ + A ++ ++ ++a+ FUN_002339-T1 901 IAIEVGDRV--GEGGAYGSLGNAYRSLGDFRKAIEYHEKDLEIAIEVsDQVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAK 983 ****99995..889999**********************9999999956677888999999999999999999888888777766 PP == domain 11 score: 12.4 bits; conditional E-value: 0.00011 TPR_MalT 15 geaeeaeelAreALal.lpeddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 g++ +a+e+ ++ L++ ++ +d ++a+ +lG a++ +gd+ +A + ++ ++a++ a+ +++ + G++++A+e ++ l FUN_002339-T1 926 GDFRKAIEYHEKDLEIaIEVSDQVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSARVGEGGAYGNLGNACQSLGDFRKAIEYHEKSL 1019 666777777777777623444555568888*************9999999999999998888888999************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetl 183 + a e + + g ++ +l++ + +d+ +A ++ ++ +++++++ ++ ay l ++ Ge + A ++ FUN_002339-T1 1020 EIAIEVSDRV--GEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVsDRVGEGSAYGNLGIAYQSMGEFRKAIEY 1094 ****999995..889999999**************999999999999945455555665555555666666666655 PP == domain 12 score: 6.8 bits; conditional E-value: 0.0059 TPR_MalT 13 sqgeaeeaeelAreALal.lpeddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 s g++ +a+e+ ++ L++ ++ +d + a+ +lG a+ +gd+ +A + ++ ++a++ + a+ ++ ++ G++++A+e ++ FUN_002339-T1 1004 SLGDFRKAIEYHEKSLEIaIEVSDRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSDRVGEGSAYGNLGIAYQSMGEFRKAIEYHEK 1097 67899999999999999834556666679999**************9999999999999988888889999999999***************** PP TPR_MalT 106 alqlaqesklea 117 lq a e + +a FUN_002339-T1 1098 HLQIAIELGNRA 1109 ***999877665 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 2.2 1.9e+03 5 22 .. 37 54 .. 35 55 .. 0.90 2 ? 1.9 0.0 0.73 6.2e+02 5 22 .. 77 94 .. 72 97 .. 0.80 3 ? 3.2 0.0 0.28 2.4e+02 5 22 .. 117 134 .. 114 136 .. 0.92 4 ? 3.2 0.0 0.28 2.4e+02 5 22 .. 157 174 .. 154 176 .. 0.92 5 ? 0.7 0.0 1.8 1.6e+03 6 22 .. 198 214 .. 197 215 .. 0.91 6 ? 3.6 0.0 0.22 1.9e+02 6 22 .. 238 254 .. 235 256 .. 0.93 7 ? 1.5 0.0 1 8.7e+02 6 22 .. 278 294 .. 277 296 .. 0.93 8 ? 3.6 0.0 0.22 1.9e+02 6 22 .. 318 334 .. 315 336 .. 0.93 9 ? 0.7 0.0 1.8 1.6e+03 6 22 .. 358 374 .. 357 375 .. 0.91 10 ? 3.6 0.0 0.22 1.9e+02 6 22 .. 398 414 .. 395 416 .. 0.93 11 ? 1.5 0.0 1 8.7e+02 6 22 .. 438 454 .. 437 456 .. 0.93 12 ? 3.6 0.0 0.22 1.9e+02 6 22 .. 478 494 .. 475 496 .. 0.93 13 ? 1.5 0.0 1 8.7e+02 6 22 .. 518 534 .. 517 536 .. 0.93 14 ? 3.2 0.0 0.28 2.4e+02 5 22 .. 557 574 .. 554 576 .. 0.92 15 ? 3.2 0.0 0.28 2.4e+02 5 22 .. 597 614 .. 594 616 .. 0.92 16 ? 1.1 0.0 1.3 1.1e+03 6 22 .. 638 654 .. 637 656 .. 0.92 17 ? 3.6 0.0 0.22 1.9e+02 6 22 .. 678 694 .. 675 696 .. 0.93 18 ? 1.5 0.0 1 8.7e+02 6 22 .. 718 734 .. 717 736 .. 0.93 19 ? 3.6 0.0 0.22 1.9e+02 6 22 .. 758 774 .. 755 776 .. 0.93 20 ? 1.5 0.0 1 8.7e+02 6 22 .. 798 814 .. 797 816 .. 0.93 21 ? 3.2 0.0 0.28 2.4e+02 5 22 .. 837 854 .. 834 856 .. 0.92 22 ? 3.0 0.0 0.33 2.8e+02 6 22 .. 878 894 .. 877 896 .. 0.92 23 ? 2.8 0.0 0.39 3.3e+02 6 22 .. 918 934 .. 917 936 .. 0.93 24 ? 3.2 0.0 0.28 2.4e+02 5 22 .. 957 974 .. 954 976 .. 0.92 25 ? 1.5 0.0 1 8.7e+02 6 22 .. 1038 1054 .. 1037 1056 .. 0.93 26 ? 2.1 0.0 0.65 5.5e+02 5 22 .. 1077 1094 .. 1074 1096 .. 0.92 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 2.2 TPR_6 5 klalsylelgdkdeAkaa 22 +la++++ gd+ +A+++ FUN_002339-T1 37 NLAYAFQSHGDFRKAIKY 54 69******99*****986 PP == domain 2 score: 1.9 bits; conditional E-value: 0.73 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +++ lgd+ +A+++ FUN_002339-T1 77 NLGNAFQSLGDFRKAIEY 94 578888888899998875 PP == domain 3 score: 3.2 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002339-T1 117 NLGNAYQSLGDFRKAIEY 134 599************986 PP == domain 4 score: 3.2 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002339-T1 157 NLGNAYQSLGDFRKAIEY 174 599************986 PP == domain 5 score: 0.7 bits; conditional E-value: 1.8 TPR_6 6 lalsylelgdkdeAkaa 22 l+ y+ lgd+ +A+++ FUN_002339-T1 198 LGTVYQSLGDFRKAIEY 214 7999**********986 PP == domain 6 score: 3.6 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 238 LGNAYRSLGDFRKAIEY 254 89************986 PP == domain 7 score: 1.5 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002339-T1 278 LGNAYDSLGDFRKAIEY 294 799***********986 PP == domain 8 score: 3.6 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 318 LGNAYRSLGDFRKAIEY 334 89************986 PP == domain 9 score: 0.7 bits; conditional E-value: 1.8 TPR_6 6 lalsylelgdkdeAkaa 22 l+ y+ lgd+ +A+++ FUN_002339-T1 358 LGTVYQSLGDFRKAIEY 374 7999**********986 PP == domain 10 score: 3.6 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 398 LGNAYRSLGDFRKAIEY 414 89************986 PP == domain 11 score: 1.5 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002339-T1 438 LGNAYDSLGDFRKAIEY 454 799***********986 PP == domain 12 score: 3.6 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 478 LGNAYRSLGDFRKAIEY 494 89************986 PP == domain 13 score: 1.5 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002339-T1 518 LGNAYDSLGDFRKAIEY 534 799***********986 PP == domain 14 score: 3.2 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002339-T1 557 NLGNAYQSLGDFRKAIEY 574 599************986 PP == domain 15 score: 3.2 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002339-T1 597 NLGNAYQSLGDFRKAIEY 614 599************986 PP == domain 16 score: 1.1 bits; conditional E-value: 1.3 TPR_6 6 lalsylelgdkdeAkaa 22 l+ y+ lgd+ +A+++ FUN_002339-T1 638 LGTVYRSLGDFRKAIEY 654 7999**********986 PP == domain 17 score: 3.6 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 678 LGNAYRSLGDFRKAIEY 694 89************986 PP == domain 18 score: 1.5 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002339-T1 718 LGNAYDSLGDFRKAIEY 734 799***********986 PP == domain 19 score: 3.6 bits; conditional E-value: 0.22 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 758 LGNAYRSLGDFRKAIEY 774 89************986 PP == domain 20 score: 1.5 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002339-T1 798 LGNAYDSLGDFRKAIEY 814 799***********986 PP == domain 21 score: 3.2 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002339-T1 837 NLGNAYQSLGDFRKAIEY 854 599************986 PP == domain 22 score: 3.0 bits; conditional E-value: 0.33 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002339-T1 878 LGNAYQTLGDFQKAIEY 894 89************986 PP == domain 23 score: 2.8 bits; conditional E-value: 0.39 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002339-T1 918 LGNAYRSLGDFRKAIEY 934 799***********986 PP == domain 24 score: 3.2 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002339-T1 957 NLGNAYQSLGDFRKAIEY 974 599************986 PP == domain 25 score: 1.5 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002339-T1 1038 LGNAYDSLGDFRKAIEY 1054 799***********986 PP == domain 26 score: 2.1 bits; conditional E-value: 0.65 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ +g++ +A+++ FUN_002339-T1 1077 NLGIAYQSMGEFRKAIEY 1094 59*************986 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.8 1.3 0.0069 5.8 51 180 .. 8 137 .. 4 146 .. 0.66 2 ! 10.3 0.2 0.00056 0.47 40 179 .. 117 256 .. 101 257 .. 0.89 3 ! 11.9 0.0 0.00018 0.16 51 180 .. 208 337 .. 193 344 .. 0.61 4 ! 13.4 0.0 6.5e-05 0.055 38 180 .. 235 377 .. 227 387 .. 0.90 5 ! 10.6 0.0 0.00045 0.39 39 179 .. 316 456 .. 306 457 .. 0.83 6 ! 13.4 0.0 6.5e-05 0.055 40 180 .. 397 537 .. 392 545 .. 0.87 7 ! 13.8 0.0 5.1e-05 0.043 42 180 .. 439 577 .. 428 590 .. 0.91 8 ! 10.3 0.1 0.00057 0.49 42 180 .. 559 697 .. 551 705 .. 0.84 9 ! 13.7 0.1 5.5e-05 0.046 42 180 .. 719 857 .. 712 868 .. 0.92 10 ! 9.3 0.1 0.0011 0.97 42 180 .. 879 1017 .. 872 1026 .. 0.91 11 ? 3.6 0.0 0.061 52 42 147 .. 1039 1144 .. 1031 1150 .. 0.90 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0069 SNAP 51 wkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadly 145 +++A e ++k ++ +++++ + y++ a ++++ d +A++ ek ei +e+g ++ + ++++ +++ +d++kAie+ e+ ++ FUN_002339-T1 8 FRKAIEYHEKHLKITMEVGDRAGEEKGYQNLAYAFQSHgDFRKAIKYHEKHLEIAIEAGHRVGEGNAYGNLGNAFQSL-GDFRKAIEYHEKHLEIA 102 555666666666666666666666666666555555444777777777777777777777777777777777777765.77777777777777776 PP SNAP 146 eqeeaealankcllkvAdlsaelekyekAieiyek 180 ++ + +++ ++ + + +l+++ kAie ek FUN_002339-T1 103 KEVSDRFGEGSAYGNLGNAYQSLGDFRKAIEYHEK 137 66666666667777777777777777777766664 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00056 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + +nay+ ++++A e ++k e+ ++++++ ++ay + ++y++ d +A+e ek +i +e g ++ + +++ +y++ +d++kA FUN_002339-T1 117 NLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVVEGSAYGNLGNAYQSLgDFRKAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYQSL-GDFRKA 211 557999999999**********************************9977999*****************9999999999******987.****** PP SNAP 135 ieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiye 179 ie+ e+ ++ + + +++ ++ + + +l+++ kAie e FUN_002339-T1 212 IEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHE 256 ****99999888888888888888888888888888888888776 PP == domain 3 score: 11.9 bits; conditional E-value: 0.00018 SNAP 51 wkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadly 145 +++A e ++k e+ +++++ +nay + ++y++ d +A+e ek ei +e g ++ + ++++ y++ +d++kAie+ e+ ++ FUN_002339-T1 208 FRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSLgDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSL-GDFRKAIEYHEKHLEIA 302 556666666666666666666666666666666666654666666666666666666666666666666666666655.66666666666666665 PP SNAP 146 eqeeaealankcllkvAdlsaelekyekAieiyek 180 + + +++ ++ + + +l+++ kAie ek FUN_002339-T1 303 IEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEK 337 55555555555555555555566666666555554 PP == domain 4 score: 13.4 bits; conditional E-value: 6.5e-05 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+ ++++A e ++k e+ +++ + +nay ++y + d +A+e ek ei +e g+ ++ + ++++ y++ +d++ FUN_002339-T1 235 YGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSLgDFRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSL-GDFR 329 5566899*****************************************9977999**********************************87.**** PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 kAie+ e+ ++ + + +++ + ++ +l+++ kAie ek FUN_002339-T1 330 KAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYQSLGDFRKAIEYHEK 377 *******99998888888888888888888888888888888888776 PP == domain 5 score: 10.6 bits; conditional E-value: 0.00045 SNAP 39 kqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlek 133 + +nay+ ++++A e ++k ++ +++ + ++ay ++y++ d +A+e ek ei +e g+ ++ + ++++ y++ +d++k FUN_002339-T1 316 GNLGNAYRSLGDFRKAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYQSLgDFRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSL-GDFRK 410 556899999999999999999999999999999999999999999999876999999999999999999999999999999999999977.99999 PP SNAP 134 AieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiye 179 Aie+ e+ ++ + + +++ + + + +l+++ kAie e FUN_002339-T1 411 AIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAIEYHE 456 9999999888777777777777777777777777777777777665 PP == domain 6 score: 13.4 bits; conditional E-value: 6.5e-05 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + +nay+ ++++A e ++k e+ +++ + +nay ++y + d +A+e ek ei +e g+ ++ + ++++ y++ +d++kA FUN_002339-T1 397 NLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSLgDFRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSL-GDFRKA 491 568999999999****************9999999****999999998769999****************99999999********987.9***** PP SNAP 135 ieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 ie+ e+ ++ + + +++ + + + +l+++ kAie ek FUN_002339-T1 492 IEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAIEYHEK 537 **99999998888888888888888888888888888888887775 PP == domain 7 score: 13.8 bits; conditional E-value: 5.1e-05 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay ++++A e ++k e+ +++++ +nay + ++y++ d +A+e ek ei +e g ++ + ++++ y++ +d++kAie FUN_002339-T1 439 GNAYDSLGDFRKAIEYHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSLgDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSL-GDFRKAIE 533 678888889999********************************9987999**********************************87.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ ++ ++ + +++ ++ + + +l+++ kAie ek FUN_002339-T1 534 YHEKHLEIAKKVGDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEK 577 ********999999999999999999999999999999999886 PP == domain 8 score: 10.3 bits; conditional E-value: 0.00057 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay+ ++++A e ++k e+ ++++++ ++ay + ++y++ d +A+e ek +i +e g ++ + +++ +y++ +d++kAie FUN_002339-T1 559 GNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVVEGSAYGNLGNAYQSLgDFRKAIEYHEKHLKIAIEVGHRVGEGSAYGSLGTVYRSL-GDFRKAIE 653 788888889999999999999999999999999999999999999876889999999999999999999888889999999999977.99999999 PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ ++ + + +++ ++ + + +l+++ kAie ek FUN_002339-T1 654 YHEKHLEIAIEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEK 697 99999888888888888888888888888888888888887775 PP == domain 9 score: 13.7 bits; conditional E-value: 5.5e-05 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +nay ++++A e ++k e+ +++++ +nay + ++y++ d +A+e ek ei +e g ++ + ++++ y++ +d++kAie FUN_002339-T1 719 GNAYDSLGDFRKAIEYHEKQLEIAIEVGNRVGEGNAYGNLGNAYRSLgDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYDSL-GDFRKAIE 813 67888888999**********************************98799***********************************87.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ ++ ++ + +++ ++ + + +l+++ kAie ek FUN_002339-T1 814 YHEKHLEIAKKVSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEK 857 *********999999999999999999999*********99886 PP == domain 10 score: 9.3 bits; conditional E-value: 0.0011 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 +nay+ ++++A e ++k e+ +++++ + ay ++y++ d +A+e ek ei +e ++ + ++++ y++ +d++kA FUN_002339-T1 879 GNAYQTLGDFQKAIEYHEKHLEIAIEVGDRVGEGGAYGSLGNAYRSLgDFRKAIEYHEKDLEIAIEVSDQVGEGSAYGNLGNAYQSL-GDFRKA 971 7999999*************************************9987999************999888888888899******987.****** PP SNAP 135 ieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 ie+ e+ ++ ++ +a ++ ++ + +l+++ kAie ek FUN_002339-T1 972 IEYHEKHLEIAKEVSARVGEGGAYGNLGNACQSLGDFRKAIEYHEK 1017 *********9999999999999999999999999999999999887 PP == domain 11 score: 3.6 bits; conditional E-value: 0.061 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 +nay ++++A e ++k e+ +k++++ ++ay + +y++ + +A+e ek +i +e g+ + + +i++ + + +++e A FUN_002339-T1 1039 GNAYDSLGDFRKAIEYHEKHLEIAKKVSDRVGEGSAYGNLGIAYQSMgEFRKAIEYHEKHLQIAIELGNRAGEGMSHHNIGNGFFSL-GQFEIA 1131 677888888999999************************999999876999******************9999999******99977.9***** PP SNAP 135 ieaYeqAadlyeq 147 ++++ A + +++ FUN_002339-T1 1132 LDKFVSAVEAFNT 1144 *****99999975 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 7.6 6.5e+03 17 31 .. 5 19 .. 4 22 .. 0.86 2 ? -0.5 0.0 2.2 1.9e+03 13 31 .. 41 59 .. 35 62 .. 0.82 3 ? -0.0 0.0 1.6 1.4e+03 14 31 .. 82 99 .. 80 102 .. 0.86 4 ? 0.9 0.0 0.82 7e+02 14 31 .. 122 139 .. 119 142 .. 0.89 5 ? 0.9 0.0 0.82 7e+02 14 31 .. 162 179 .. 159 182 .. 0.89 6 ? 0.9 0.0 0.85 7.2e+02 14 31 .. 202 219 .. 200 222 .. 0.88 7 ? 0.6 0.0 1 8.5e+02 14 31 .. 242 259 .. 239 262 .. 0.88 8 ? 0.3 0.0 1.3 1.1e+03 14 31 .. 282 299 .. 281 302 .. 0.87 9 ? 0.6 0.0 0.99 8.5e+02 14 31 .. 322 339 .. 319 342 .. 0.88 10 ? 0.9 0.0 0.85 7.2e+02 14 31 .. 362 379 .. 360 382 .. 0.88 11 ? 0.6 0.0 1 8.5e+02 14 31 .. 402 419 .. 399 422 .. 0.88 12 ? 0.3 0.0 1.3 1.1e+03 14 31 .. 442 459 .. 441 462 .. 0.87 13 ? 0.6 0.0 1 8.5e+02 14 31 .. 482 499 .. 479 502 .. 0.88 14 ? 0.3 0.0 1.3 1.1e+03 14 31 .. 522 539 .. 521 542 .. 0.87 15 ? 0.9 0.0 0.82 7e+02 14 31 .. 562 579 .. 559 582 .. 0.89 16 ? 0.9 0.0 0.82 7e+02 14 31 .. 602 619 .. 599 622 .. 0.89 17 ? 0.6 0.0 1 8.7e+02 14 31 .. 642 659 .. 640 662 .. 0.87 18 ? 0.6 0.0 1 8.5e+02 14 31 .. 682 699 .. 679 702 .. 0.88 19 ? 1.9 0.0 0.4 3.4e+02 14 31 .. 722 739 .. 720 743 .. 0.89 20 ? 0.6 0.0 1 8.5e+02 14 31 .. 762 779 .. 759 782 .. 0.88 21 ? 0.3 0.0 1.3 1.1e+03 14 31 .. 802 819 .. 801 822 .. 0.87 22 ? 0.9 0.0 0.82 7e+02 14 31 .. 842 859 .. 839 862 .. 0.89 23 ? 1.1 0.0 0.7 5.9e+02 14 31 .. 882 899 .. 878 902 .. 0.91 24 ? 0.4 0.0 1.2 9.9e+02 14 31 .. 922 939 .. 921 942 .. 0.87 25 ? 0.9 0.0 0.82 7e+02 14 31 .. 962 979 .. 959 982 .. 0.89 26 ? -1.4 0.0 4.4 3.7e+03 17 31 .. 1005 1019 .. 1004 1021 .. 0.88 27 ? 0.3 0.0 1.3 1.1e+03 14 31 .. 1042 1059 .. 1041 1062 .. 0.87 28 ? 3.6 0.0 0.12 99 12 31 .. 1080 1099 .. 1076 1102 .. 0.89 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 7.6 DUF2977 17 vGgledgidvdednl 31 G ++++i+++e+ l FUN_002339-T1 5 QGCFRKAIEYHEKHL 19 5899*******9987 PP == domain 2 score: -0.5 bits; conditional E-value: 2.2 DUF2977 13 sYvlvGgledgidvdednl 31 + G ++++i ++e+ l FUN_002339-T1 41 AFQSHGDFRKAIKYHEKHL 59 56778**********9987 PP == domain 3 score: -0.0 bits; conditional E-value: 1.6 DUF2977 14 YvlvGgledgidvdednl 31 + G ++++i+++e+ l FUN_002339-T1 82 FQSLGDFRKAIEYHEKHL 99 5568***********987 PP == domain 4 score: 0.9 bits; conditional E-value: 0.82 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 122 YQSLGDFRKAIEYHEKHL 139 7889***********987 PP == domain 5 score: 0.9 bits; conditional E-value: 0.82 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 162 YQSLGDFRKAIEYHEKHL 179 7889***********987 PP == domain 6 score: 0.9 bits; conditional E-value: 0.85 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 202 YQSLGDFRKAIEYHEKHL 219 7789***********987 PP == domain 7 score: 0.6 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 242 YRSLGDFRKAIEYHEKHL 259 7789***********987 PP == domain 8 score: 0.3 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 282 YDSLGDFRKAIEYHEKHL 299 6678***********987 PP == domain 9 score: 0.6 bits; conditional E-value: 0.99 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 322 YRSLGDFRKAIEYHEKHL 339 7789***********987 PP == domain 10 score: 0.9 bits; conditional E-value: 0.85 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 362 YQSLGDFRKAIEYHEKHL 379 7789***********987 PP == domain 11 score: 0.6 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 402 YRSLGDFRKAIEYHEKHL 419 7789***********987 PP == domain 12 score: 0.3 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 442 YDSLGDFRKAIEYHEKHL 459 6678***********987 PP == domain 13 score: 0.6 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 482 YRSLGDFRKAIEYHEKHL 499 7789***********987 PP == domain 14 score: 0.3 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 522 YDSLGDFRKAIEYHEKHL 539 6678***********987 PP == domain 15 score: 0.9 bits; conditional E-value: 0.82 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 562 YQSLGDFRKAIEYHEKHL 579 7889***********987 PP == domain 16 score: 0.9 bits; conditional E-value: 0.82 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 602 YQSLGDFRKAIEYHEKHL 619 7889***********987 PP == domain 17 score: 0.6 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 642 YRSLGDFRKAIEYHEKHL 659 7789***********987 PP == domain 18 score: 0.6 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 682 YRSLGDFRKAIEYHEKHL 699 7789***********987 PP == domain 19 score: 1.9 bits; conditional E-value: 0.4 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e++l FUN_002339-T1 722 YDSLGDFRKAIEYHEKQL 739 6778***********998 PP == domain 20 score: 0.6 bits; conditional E-value: 1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 762 YRSLGDFRKAIEYHEKHL 779 7789***********987 PP == domain 21 score: 0.3 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 802 YDSLGDFRKAIEYHEKHL 819 6678***********987 PP == domain 22 score: 0.9 bits; conditional E-value: 0.82 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 842 YQSLGDFRKAIEYHEKHL 859 7889***********987 PP == domain 23 score: 1.1 bits; conditional E-value: 0.7 DUF2977 14 YvlvGgledgidvdednl 31 Y + G ++++i+++e+ l FUN_002339-T1 882 YQTLGDFQKAIEYHEKHL 899 899************987 PP == domain 24 score: 0.4 bits; conditional E-value: 1.2 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 922 YRSLGDFRKAIEYHEKDL 939 7789**********9877 PP == domain 25 score: 0.9 bits; conditional E-value: 0.82 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 962 YQSLGDFRKAIEYHEKHL 979 7889***********987 PP == domain 26 score: -1.4 bits; conditional E-value: 4.4 DUF2977 17 vGgledgidvdednl 31 G ++++i+++e+ l FUN_002339-T1 1005 LGDFRKAIEYHEKSL 1019 699********9876 PP == domain 27 score: 0.3 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002339-T1 1042 YDSLGDFRKAIEYHEKHL 1059 6678***********987 PP == domain 28 score: 3.6 bits; conditional E-value: 0.12 DUF2977 12 isYvlvGgledgidvdednl 31 i Y +G ++++i+++e+ l FUN_002339-T1 1080 IAYQSMGEFRKAIEYHEKHL 1099 899**************987 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.2 0.056 48 3 58 .. 38 99 .. 37 105 .. 0.79 2 ? 4.5 0.2 0.08 68 3 53 .. 118 174 .. 112 184 .. 0.66 3 ! 7.9 0.0 0.0069 5.9 3 59 .. 198 260 .. 197 265 .. 0.81 4 ! 8.8 0.2 0.0036 3.1 3 58 .. 278 339 .. 270 343 .. 0.82 5 ! 7.9 0.0 0.0071 6 3 58 .. 358 419 .. 357 424 .. 0.81 6 ! 7.9 0.3 0.0069 5.9 3 58 .. 398 459 .. 391 466 .. 0.84 7 ! 9.0 0.2 0.0032 2.7 3 58 .. 438 499 .. 429 504 .. 0.82 8 ! 8.1 0.1 0.0061 5.2 3 59 .. 478 540 .. 477 545 .. 0.85 9 ? 4.1 0.2 0.11 95 4 53 .. 519 574 .. 509 586 .. 0.54 10 ? 4.3 0.2 0.094 80 3 53 .. 558 614 .. 557 622 .. 0.63 11 ? 6.3 0.0 0.023 19 3 58 .. 598 659 .. 597 664 .. 0.80 12 ! 8.5 0.0 0.0047 4 3 58 .. 638 699 .. 637 704 .. 0.83 13 ? 6.8 0.2 0.016 14 3 53 .. 678 734 .. 677 742 .. 0.84 14 ! 9.3 0.2 0.0025 2.2 3 59 .. 718 780 .. 709 784 .. 0.82 15 ! 8.1 0.2 0.0059 5.1 3 59 .. 758 820 .. 757 826 .. 0.85 16 ? 4.1 0.2 0.11 94 4 53 .. 799 854 .. 789 866 .. 0.53 17 ? 6.1 0.2 0.025 22 3 58 .. 838 899 .. 829 904 .. 0.76 18 ? 5.9 0.2 0.03 26 3 53 .. 878 934 .. 877 942 .. 0.79 19 ? 6.4 0.2 0.02 17 3 58 .. 918 979 .. 917 986 .. 0.81 20 ? 2.6 0.1 0.33 2.8e+02 3 19 .. 958 974 .. 957 1023 .. 0.73 21 ? 3.2 0.0 0.21 1.8e+02 20 58 .. 1019 1059 .. 997 1064 .. 0.62 22 ? -1.7 0.0 7 6e+03 3 19 .. 1078 1094 .. 1077 1096 .. 0.90 23 ? -0.7 0.0 3.5 3e+03 4 27 .. 1119 1142 .. 1117 1151 .. 0.78 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.056 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 la a+ +gd++ A+++ le a++++ A+ +lG a+ +g++ +A+++ ++ l FUN_002339-T1 38 LAYAFQSHGDFRKAIKYhekhLEIAIEAGhrVGEGNAYGNLGNAFQSLGDFRKAIEYHEKHL 99 68888899999999864444499999999996689999999999999999999998866666 PP == domain 2 score: 4.5 bits; conditional E-value: 0.08 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ e l+ A+ +lG a+ +g++ +A+++ FUN_002339-T1 118 LGNAYQSLGDFRKAIEYHEKHLEIAkevsdrVVEGSAYGNLGNAYQSLGDFRKAIEY 174 677788888888887765544444445556655666777777777777777777766 PP == domain 3 score: 7.9 bits; conditional E-value: 0.0069 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++ + +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l+ FUN_002339-T1 198 LGTVYQSLGDFRKAIEYhekhLEIAIEVGnrVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLE 260 678888899999998654444889999999977899******************998776665 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0036 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l FUN_002339-T1 278 LGNAYDSLGDFRKAIEYhekhLEIAIEVGnrVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 339 68888889999999865444488888888**77999*******************9866665 PP == domain 5 score: 7.9 bits; conditional E-value: 0.0071 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++ + +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l FUN_002339-T1 358 LGTVYQSLGDFRKAIEYhekhLEIAIEVGnrVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 419 678888899999998654444889999999977899******************99877666 PP == domain 6 score: 7.9 bits; conditional E-value: 0.0069 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ ++ l FUN_002339-T1 398 LGNAYRSLGDFRKAIEYhekhLEIAIEVGhrVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHL 459 79999999999999875444488899999997789999999999999999999999876666 PP == domain 7 score: 9.0 bits; conditional E-value: 0.0032 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l FUN_002339-T1 438 LGNAYDSLGDFRKAIEYhekhLEIAIEVGnrVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 499 68888888888888765444488888888**77999*******************9877666 PP == domain 8 score: 8.1 bits; conditional E-value: 0.0061 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a++ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ ++ l+ FUN_002339-T1 478 LGNAYRSLGDFRKAIEYhekhLEIAIEVGhrVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLE 540 899***********975444499999999**77999******************998777665 PP == domain 9 score: 4.1 bits; conditional E-value: 0.11 TPR_16 4 araalaagdyddAaaaleaalrrn.............PeaaaAllglGlallrqgrlaeAaaa 53 ++a+ +gd++ A++ ++ A+ +lG a+ +g++ +A+++ FUN_002339-T1 519 GNAYDSLGDFRKAIE-------YHekhleiakkvgdrVGEGSAYGNLGNAYQSLGDFRKAIEY 574 334444444444443.......33333333355556644566666666666666666666665 PP == domain 10 score: 4.3 bits; conditional E-value: 0.094 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ e l+ A+ +lG a+ +g++ +A+++ FUN_002339-T1 558 LGNAYQSLGDFRKAIEYHEKHLEIAkevsdrVVEGSAYGNLGNAYQSLGDFRKAIEY 614 678888888888888775544444445556655666677777777666666666665 PP == domain 11 score: 6.3 bits; conditional E-value: 0.023 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ l+ a++ + A+ lG ++ +g++ +A+++ ++ l FUN_002339-T1 598 LGNAYQSLGDFRKAIEYhekhLKIAIEVGhrVGEGSAYGSLGTVYRSLGDFRKAIEYHEKHL 659 7999**********986333377777777996689999999999999999999998866666 PP == domain 12 score: 8.5 bits; conditional E-value: 0.0047 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++ ++ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l FUN_002339-T1 638 LGTVYRSLGDFRKAIEYhekhLEIAIEVGnrVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHL 699 688899999999998754444999999999977899*******************9877666 PP == domain 13 score: 6.8 bits; conditional E-value: 0.016 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a++ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ FUN_002339-T1 678 LGNAYRSLGDFRKAIEYhekhLEIAIEVGhrVGEGNAYGSLGNAYDSLGDFRKAIEY 734 799***********9754444888999999977899999999999999999999975 PP == domain 14 score: 9.3 bits; conditional E-value: 0.0025 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ ++ l+ FUN_002339-T1 718 LGNAYDSLGDFRKAIEYhekqLEIAIEVGnrVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLE 780 68888899999999764333388888888**77999*******************98776665 PP == domain 15 score: 8.1 bits; conditional E-value: 0.0059 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a++ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ ++ l+ FUN_002339-T1 758 LGNAYRSLGDFRKAIEYhekhLEIAIEVGhrVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLE 820 899***********975444499999999**77999*******************98777765 PP == domain 16 score: 4.1 bits; conditional E-value: 0.11 TPR_16 4 araalaagdyddAaaaleaalrrn.............PeaaaAllglGlallrqgrlaeAaaa 53 ++a+ +gd++ A++ ++ A+ +lG a+ +g++ +A+++ FUN_002339-T1 799 GNAYDSLGDFRKAIE-------YHekhleiakkvsdrVGEGSAYGNLGNAYQSLGDFRKAIEY 854 333333444444433.......33333333355556644566666666666666666666665 PP == domain 17 score: 6.1 bits; conditional E-value: 0.025 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ e l+ A+ +lG a+ +g++++A+++ ++ l FUN_002339-T1 838 LGNAYQSLGDFRKAIEYHEKHLEIAkevsdrVGEGGAYGNLGNAYQTLGDFQKAIEYHEKHL 899 67788888888888877655555446677885678899999999999999999998866665 PP == domain 18 score: 5.9 bits; conditional E-value: 0.03 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ FUN_002339-T1 878 LGNAYQTLGDFQKAIEYhekhLEIAIEVGdrVGEGGAYGSLGNAYRSLGDFRKAIEY 934 789999999999998654444888888888866788999999999999999999865 PP == domain 19 score: 6.4 bits; conditional E-value: 0.02 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a++ +gd++ A+++ le a++ A+ +lG a+ +g++ +A+++ ++ l FUN_002339-T1 918 LGNAYRSLGDFRKAIEYhekdLEIAIEVSdqVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHL 979 79999999999999875444488888888996688999999999999999999998866666 PP == domain 20 score: 2.6 bits; conditional E-value: 0.33 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002339-T1 958 LGNAYQSLGDFRKAIEY 974 79999999999999986 PP == domain 21 score: 3.2 bits; conditional E-value: 0.21 TPR_16 20 leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 le a++ A+ lG a+ +g++ +A+++ ++ l FUN_002339-T1 1019 LEIAIEVSdrVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHL 1059 44444444665567788888888888888888887766555 PP == domain 22 score: -1.7 bits; conditional E-value: 7 TPR_16 3 laraalaagdyddAaaa 19 l+ a+ +g+++ A+++ FUN_002339-T1 1078 LGIAYQSMGEFRKAIEY 1094 7999**********985 PP == domain 23 score: -0.7 bits; conditional E-value: 3.5 TPR_16 4 araalaagdyddAaaaleaalrrn 27 ++ ++ +g+++ A+ + a++++ FUN_002339-T1 1119 GNGFFSLGQFEIALDKFVSAVEAF 1142 667788899999998888888776 PP >> DUF7542 Family of unknown function (DUF7542) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.8 0.1 9.1 7.7e+03 18 35 .. 41 58 .. 37 67 .. 0.83 2 ? 2.7 0.0 0.17 1.5e+02 17 35 .. 80 98 .. 74 105 .. 0.87 3 ? 2.0 0.0 0.28 2.4e+02 17 35 .. 120 138 .. 114 144 .. 0.87 4 ? 2.8 0.0 0.15 1.3e+02 15 35 .. 158 178 .. 146 190 .. 0.81 5 ? 1.6 0.0 0.37 3.2e+02 17 35 .. 200 218 .. 194 225 .. 0.86 6 ? 1.7 0.0 0.35 3e+02 17 35 .. 240 258 .. 235 270 .. 0.84 7 ? 3.3 0.0 0.11 97 17 35 .. 280 298 .. 274 305 .. 0.86 8 ? 1.5 0.0 0.4 3.4e+02 17 35 .. 320 338 .. 315 350 .. 0.84 9 ? 1.6 0.0 0.37 3.2e+02 17 35 .. 360 378 .. 354 385 .. 0.86 10 ? 1.7 0.0 0.35 3e+02 17 35 .. 400 418 .. 395 430 .. 0.84 11 ? 3.3 0.0 0.11 97 17 35 .. 440 458 .. 434 465 .. 0.86 12 ? 1.7 0.0 0.35 3e+02 17 35 .. 480 498 .. 475 510 .. 0.84 13 ? 3.1 0.0 0.13 1.1e+02 17 35 .. 520 538 .. 514 544 .. 0.88 14 ? 2.2 0.0 0.23 2e+02 17 35 .. 560 578 .. 554 592 .. 0.87 15 ? 2.8 0.0 0.15 1.3e+02 15 35 .. 598 618 .. 585 629 .. 0.81 16 ? 0.9 0.0 0.63 5.3e+02 17 35 .. 640 658 .. 634 665 .. 0.86 17 ? 1.7 0.0 0.35 3e+02 17 35 .. 680 698 .. 675 710 .. 0.84 18 ? 3.5 0.0 0.094 80 17 36 .. 720 739 .. 714 745 .. 0.87 19 ? 1.7 0.0 0.35 3e+02 17 35 .. 760 778 .. 755 790 .. 0.84 20 ? 3.3 0.0 0.11 94 17 35 .. 800 818 .. 794 834 .. 0.87 21 ? 2.2 0.0 0.24 2e+02 17 35 .. 840 858 .. 833 869 .. 0.87 22 ? -2.4 0.0 6.5 5.5e+03 17 35 .. 880 898 .. 876 903 .. 0.86 23 ? 2.6 0.0 0.18 1.5e+02 17 36 .. 920 939 .. 914 952 .. 0.86 24 ? 2.3 0.0 0.22 1.9e+02 17 35 .. 960 978 .. 953 991 .. 0.86 25 ? -0.9 0.0 2.3 1.9e+03 18 35 .. 1001 1018 .. 996 1025 .. 0.84 26 ? 3.2 0.0 0.12 99 17 35 .. 1040 1058 .. 1034 1070 .. 0.88 27 ? -0.5 0.0 1.7 1.4e+03 18 35 .. 1081 1098 .. 1076 1104 .. 0.87 Alignments for each domain: == domain 1 score: -2.8 bits; conditional E-value: 9.1 DUF7542 18 tfdslraARealddHese 35 +f+s ++ R+a++ He++ FUN_002339-T1 41 AFQSHGDFRKAIKYHEKH 58 78999999*******976 PP == domain 2 score: 2.7 bits; conditional E-value: 0.17 DUF7542 17 etfdslraARealddHese 35 ++f+sl++ R+a++ He++ FUN_002339-T1 80 NAFQSLGDFRKAIEYHEKH 98 78***************86 PP == domain 3 score: 2.0 bits; conditional E-value: 0.28 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002339-T1 120 NAYQSLGDFRKAIEYHEKH 138 689**************76 PP == domain 4 score: 2.8 bits; conditional E-value: 0.15 DUF7542 15 feetfdslraARealddHese 35 + ++++sl++ R+a++ He++ FUN_002339-T1 158 LGNAYQSLGDFRKAIEYHEKH 178 5679***************75 PP == domain 5 score: 1.6 bits; conditional E-value: 0.37 DUF7542 17 etfdslraARealddHese 35 + ++sl++ R+a++ He++ FUN_002339-T1 200 TVYQSLGDFRKAIEYHEKH 218 679**************86 PP == domain 6 score: 1.7 bits; conditional E-value: 0.35 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002339-T1 240 NAYRSLGDFRKAIEYHEKH 258 6899*************86 PP == domain 7 score: 3.3 bits; conditional E-value: 0.11 DUF7542 17 etfdslraARealddHese 35 +++dsl++ R+a++ He++ FUN_002339-T1 280 NAYDSLGDFRKAIEYHEKH 298 78***************86 PP == domain 8 score: 1.5 bits; conditional E-value: 0.4 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002339-T1 320 NAYRSLGDFRKAIEYHEKH 338 6899*************85 PP == domain 9 score: 1.6 bits; conditional E-value: 0.37 DUF7542 17 etfdslraARealddHese 35 + ++sl++ R+a++ He++ FUN_002339-T1 360 TVYQSLGDFRKAIEYHEKH 378 679**************86 PP == domain 10 score: 1.7 bits; conditional E-value: 0.35 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002339-T1 400 NAYRSLGDFRKAIEYHEKH 418 6899*************86 PP == domain 11 score: 3.3 bits; conditional E-value: 0.11 DUF7542 17 etfdslraARealddHese 35 +++dsl++ R+a++ He++ FUN_002339-T1 440 NAYDSLGDFRKAIEYHEKH 458 78***************86 PP == domain 12 score: 1.7 bits; conditional E-value: 0.35 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002339-T1 480 NAYRSLGDFRKAIEYHEKH 498 6899*************86 PP == domain 13 score: 3.1 bits; conditional E-value: 0.13 DUF7542 17 etfdslraARealddHese 35 +++dsl++ R+a++ He++ FUN_002339-T1 520 NAYDSLGDFRKAIEYHEKH 538 78***************76 PP == domain 14 score: 2.2 bits; conditional E-value: 0.23 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002339-T1 560 NAYQSLGDFRKAIEYHEKH 578 689**************86 PP == domain 15 score: 2.8 bits; conditional E-value: 0.15 DUF7542 15 feetfdslraARealddHese 35 + ++++sl++ R+a++ He++ FUN_002339-T1 598 LGNAYQSLGDFRKAIEYHEKH 618 5689***************75 PP == domain 16 score: 0.9 bits; conditional E-value: 0.63 DUF7542 17 etfdslraARealddHese 35 + + sl++ R+a++ He++ FUN_002339-T1 640 TVYRSLGDFRKAIEYHEKH 658 6799*************86 PP == domain 17 score: 1.7 bits; conditional E-value: 0.35 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002339-T1 680 NAYRSLGDFRKAIEYHEKH 698 6899*************86 PP == domain 18 score: 3.5 bits; conditional E-value: 0.094 DUF7542 17 etfdslraARealddHeset 36 +++dsl++ R+a++ He++ FUN_002339-T1 720 NAYDSLGDFRKAIEYHEKQL 739 78***************875 PP == domain 19 score: 1.7 bits; conditional E-value: 0.35 DUF7542 17 etfdslraARealddHese 35 +++ sl++ R+a++ He++ FUN_002339-T1 760 NAYRSLGDFRKAIEYHEKH 778 6899*************86 PP == domain 20 score: 3.3 bits; conditional E-value: 0.11 DUF7542 17 etfdslraARealddHese 35 +++dsl++ R+a++ He++ FUN_002339-T1 800 NAYDSLGDFRKAIEYHEKH 818 78***************86 PP == domain 21 score: 2.2 bits; conditional E-value: 0.24 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002339-T1 840 NAYQSLGDFRKAIEYHEKH 858 789*************986 PP == domain 22 score: -2.4 bits; conditional E-value: 6.5 DUF7542 17 etfdslraARealddHese 35 +++++l++ +a++ He++ FUN_002339-T1 880 NAYQTLGDFQKAIEYHEKH 898 68999***********975 PP == domain 23 score: 2.6 bits; conditional E-value: 0.18 DUF7542 17 etfdslraARealddHeset 36 +++ sl++ R+a++ He++ FUN_002339-T1 920 NAYRSLGDFRKAIEYHEKDL 939 6899*************986 PP == domain 24 score: 2.3 bits; conditional E-value: 0.22 DUF7542 17 etfdslraARealddHese 35 ++++sl++ R+a++ He++ FUN_002339-T1 960 NAYQSLGDFRKAIEYHEKH 978 789*************986 PP == domain 25 score: -0.9 bits; conditional E-value: 2.3 DUF7542 18 tfdslraARealddHese 35 + +sl++ R+a++ He+ FUN_002339-T1 1001 ACQSLGDFRKAIEYHEKS 1018 56899**********986 PP == domain 26 score: 3.2 bits; conditional E-value: 0.12 DUF7542 17 etfdslraARealddHese 35 +++dsl++ R+a++ He++ FUN_002339-T1 1040 NAYDSLGDFRKAIEYHEKH 1058 78***************86 PP == domain 27 score: -0.5 bits; conditional E-value: 1.7 DUF7542 18 tfdslraARealddHese 35 +++s+++ R+a++ He++ FUN_002339-T1 1081 AYQSMGEFRKAIEYHEKH 1098 7999************86 PP >> DBD_Tnp_Mut MuDR family transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 6.1 5.2e+03 9 22 .. 41 54 .. 39 56 .. 0.86 2 ? 3.8 0.0 0.072 62 6 23 .. 78 95 .. 74 109 .. 0.87 3 ? 0.7 0.0 0.71 6e+02 6 23 .. 118 135 .. 116 150 .. 0.85 4 ? 0.5 0.0 0.83 7.1e+02 6 23 .. 158 175 .. 156 183 .. 0.88 5 ? 0.9 0.0 0.62 5.3e+02 6 22 .. 198 214 .. 196 220 .. 0.89 6 ? -0.2 0.0 1.3 1.1e+03 6 22 .. 238 254 .. 235 260 .. 0.88 7 ? 1.2 0.0 0.49 4.2e+02 6 22 .. 278 294 .. 275 300 .. 0.89 8 ? -0.1 0.0 1.2 1e+03 6 23 .. 318 335 .. 315 343 .. 0.88 9 ? 0.9 0.0 0.62 5.3e+02 6 22 .. 358 374 .. 356 380 .. 0.89 10 ? -0.2 0.0 1.3 1.1e+03 6 22 .. 398 414 .. 395 420 .. 0.88 11 ? 1.2 0.0 0.49 4.2e+02 6 22 .. 438 454 .. 435 460 .. 0.89 12 ? -0.2 0.0 1.3 1.1e+03 6 22 .. 478 494 .. 475 500 .. 0.88 13 ? 1.4 0.0 0.43 3.7e+02 6 23 .. 518 535 .. 515 547 .. 0.88 14 ? 0.7 0.0 0.71 6e+02 6 23 .. 558 575 .. 556 590 .. 0.85 15 ? 0.5 0.0 0.83 7.1e+02 6 23 .. 598 615 .. 596 623 .. 0.88 16 ? 0.2 0.0 0.98 8.3e+02 6 22 .. 638 654 .. 636 659 .. 0.88 17 ? -0.2 0.0 1.3 1.1e+03 6 22 .. 678 694 .. 675 700 .. 0.88 18 ? 1.3 0.0 0.47 4e+02 6 23 .. 718 735 .. 715 742 .. 0.89 19 ? -0.2 0.0 1.3 1.1e+03 6 22 .. 758 774 .. 755 780 .. 0.88 20 ? 1.6 0.0 0.35 3e+02 6 23 .. 798 815 .. 794 829 .. 0.84 21 ? 0.5 0.0 0.82 7e+02 6 23 .. 838 855 .. 836 867 .. 0.88 22 ? -0.2 0.0 1.4 1.2e+03 6 23 .. 918 935 .. 916 942 .. 0.88 23 ? 0.6 0.0 0.75 6.4e+02 6 23 .. 958 975 .. 956 989 .. 0.86 24 ? -2.3 0.0 6 5.1e+03 7 22 .. 999 1014 .. 997 1016 .. 0.81 25 ? 1.6 0.0 0.35 3e+02 6 23 .. 1038 1055 .. 1034 1069 .. 0.84 26 ? 0.6 0.0 0.75 6.4e+02 6 23 .. 1078 1095 .. 1076 1103 .. 0.88 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 6.1 DBD_Tnp_Mut 9 kFkdleefrkAlrk 22 F++ +frkA++ FUN_002339-T1 41 AFQSHGDFRKAIKY 54 59999******986 PP == domain 2 score: 3.8 bits; conditional E-value: 0.072 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G F++l +frkA++ + FUN_002339-T1 78 LGNAFQSLGDFRKAIEYH 95 799***********9865 PP == domain 3 score: 0.7 bits; conditional E-value: 0.71 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 118 LGNAYQSLGDFRKAIEYH 135 69999*********9865 PP == domain 4 score: 0.5 bits; conditional E-value: 0.83 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 158 LGNAYQSLGDFRKAIEYH 175 69999*********9865 PP == domain 5 score: 0.9 bits; conditional E-value: 0.62 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G ++++l +frkA++ FUN_002339-T1 198 LGTVYQSLGDFRKAIEY 214 7999**********986 PP == domain 6 score: -0.2 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002339-T1 238 LGNAYRSLGDFRKAIEY 254 68999*********986 PP == domain 7 score: 1.2 bits; conditional E-value: 0.49 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002339-T1 278 LGNAYDSLGDFRKAIEY 294 7999**********986 PP == domain 8 score: -0.1 bits; conditional E-value: 1.2 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G + +l +frkA++ + FUN_002339-T1 318 LGNAYRSLGDFRKAIEYH 335 68999*********9865 PP == domain 9 score: 0.9 bits; conditional E-value: 0.62 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G ++++l +frkA++ FUN_002339-T1 358 LGTVYQSLGDFRKAIEY 374 7999**********986 PP == domain 10 score: -0.2 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002339-T1 398 LGNAYRSLGDFRKAIEY 414 68999*********986 PP == domain 11 score: 1.2 bits; conditional E-value: 0.49 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002339-T1 438 LGNAYDSLGDFRKAIEY 454 7999**********986 PP == domain 12 score: -0.2 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002339-T1 478 LGNAYRSLGDFRKAIEY 494 68999*********986 PP == domain 13 score: 1.4 bits; conditional E-value: 0.43 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 518 LGNAYDSLGDFRKAIEYH 535 7999**********9865 PP == domain 14 score: 0.7 bits; conditional E-value: 0.71 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 558 LGNAYQSLGDFRKAIEYH 575 69999*********9865 PP == domain 15 score: 0.5 bits; conditional E-value: 0.83 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 598 LGNAYQSLGDFRKAIEYH 615 69999*********9865 PP == domain 16 score: 0.2 bits; conditional E-value: 0.98 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G ++ +l +frkA++ FUN_002339-T1 638 LGTVYRSLGDFRKAIEY 654 69999*********986 PP == domain 17 score: -0.2 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002339-T1 678 LGNAYRSLGDFRKAIEY 694 68999*********986 PP == domain 18 score: 1.3 bits; conditional E-value: 0.47 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 718 LGNAYDSLGDFRKAIEYH 735 7999**********9865 PP == domain 19 score: -0.2 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002339-T1 758 LGNAYRSLGDFRKAIEY 774 68999*********986 PP == domain 20 score: 1.6 bits; conditional E-value: 0.35 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 798 LGNAYDSLGDFRKAIEYH 815 7999**********9865 PP == domain 21 score: 0.5 bits; conditional E-value: 0.82 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 838 LGNAYQSLGDFRKAIEYH 855 69999*********9865 PP == domain 22 score: -0.2 bits; conditional E-value: 1.4 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G + +l +frkA++ + FUN_002339-T1 918 LGNAYRSLGDFRKAIEYH 935 689999********9865 PP == domain 23 score: 0.6 bits; conditional E-value: 0.75 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 958 LGNAYQSLGDFRKAIEYH 975 69999*********9865 PP == domain 24 score: -2.3 bits; conditional E-value: 6 DBD_Tnp_Mut 7 GlkFkdleefrkAlrk 22 G ++l +frkA++ FUN_002339-T1 999 GNACQSLGDFRKAIEY 1014 6677899******975 PP == domain 25 score: 1.6 bits; conditional E-value: 0.35 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002339-T1 1038 LGNAYDSLGDFRKAIEYH 1055 7999**********9865 PP == domain 26 score: 0.6 bits; conditional E-value: 0.75 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G ++++ efrkA++ + FUN_002339-T1 1078 LGIAYQSMGEFRKAIEYH 1095 69999*********9865 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.2 0.023 19 37 73 .. 33 69 .. 11 70 .. 0.90 2 ? 0.6 0.0 0.63 5.4e+02 38 64 .. 74 100 .. 72 109 .. 0.87 3 ? 2.4 0.3 0.19 1.6e+02 37 64 .. 113 140 .. 89 150 .. 0.84 4 ? 3.7 0.0 0.071 61 38 72 .. 154 188 .. 144 190 .. 0.91 5 ? 1.9 0.0 0.26 2.2e+02 38 70 .. 194 226 .. 192 230 .. 0.85 6 ? 4.8 0.0 0.035 29 38 73 .. 234 269 .. 231 270 .. 0.91 7 ? 1.0 0.0 0.48 4.1e+02 38 70 .. 274 306 .. 272 310 .. 0.85 8 ? 3.5 0.0 0.083 70 38 72 .. 314 348 .. 311 350 .. 0.90 9 ? 1.9 0.0 0.26 2.2e+02 38 70 .. 354 386 .. 352 390 .. 0.85 10 ? 4.8 0.0 0.035 29 38 73 .. 394 429 .. 391 430 .. 0.91 11 ? 1.0 0.0 0.48 4.1e+02 38 70 .. 434 466 .. 432 470 .. 0.85 12 ? 4.8 0.0 0.035 29 38 73 .. 474 509 .. 471 510 .. 0.91 13 ? 0.5 0.0 0.71 6.1e+02 38 66 .. 514 542 .. 512 551 .. 0.84 14 ? 2.1 0.0 0.22 1.9e+02 38 64 .. 554 580 .. 551 590 .. 0.88 15 ? 3.7 0.0 0.073 62 38 72 .. 594 628 .. 588 630 .. 0.90 16 ? 1.5 0.0 0.35 2.9e+02 38 70 .. 634 666 .. 632 670 .. 0.85 17 ? 4.8 0.0 0.035 29 38 73 .. 674 709 .. 671 710 .. 0.91 18 ? 0.7 0.0 0.61 5.2e+02 38 70 .. 714 746 .. 712 750 .. 0.84 19 ? 4.8 0.0 0.032 28 38 73 .. 754 789 .. 744 790 .. 0.92 20 ? 0.1 0.0 0.91 7.8e+02 38 64 .. 794 820 .. 792 830 .. 0.85 21 ? 2.6 0.2 0.15 1.3e+02 37 64 .. 833 860 .. 809 870 .. 0.81 22 ? 3.3 0.0 0.099 85 38 67 .. 874 903 .. 862 909 .. 0.88 23 ? -0.9 0.0 1.8 1.5e+03 39 63 .. 915 939 .. 913 949 .. 0.84 24 ? 2.5 0.1 0.17 1.4e+02 38 65 .. 954 981 .. 936 989 .. 0.87 25 ? 2.7 0.1 0.15 1.2e+02 38 105 .. 1034 1101 .. 1016 1154 .. 0.63 26 ? 0.5 0.0 0.68 5.8e+02 39 71 .. 1075 1107 .. 1072 1183 .. 0.63 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.023 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 +++++la + ++gd+++A+k+ e+ +e ++ +gh + FUN_002339-T1 33 KGYQNLAYAFQSHGDFRKAIKYHEKHLEIAIEAGHRV 69 68999***********************999999975 PP == domain 2 score: 0.6 bits; conditional E-value: 0.63 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ + + gd+++A+++ e+ +e FUN_002339-T1 74 AYGNLGNAFQSLGDFRKAIEYHEKHLE 100 78899****************999876 PP == domain 3 score: 2.4 bits; conditional E-value: 0.19 RPN7 37 raledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002339-T1 113 SAYGNLGNAYQSLGDFRKAIEYHEKHLE 140 57899*****************999876 PP == domain 4 score: 3.7 bits; conditional E-value: 0.071 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + gd+++A+++ e+ ++ ++ gh FUN_002339-T1 154 AYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEVGHR 188 7889********************99998888886 PP == domain 5 score: 1.9 bits; conditional E-value: 0.26 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l+ y + gd+++A+++ e+ +e ++ g FUN_002339-T1 194 AYGSLGTVYQSLGDFRKAIEYHEKHLEIAIEVG 226 6778999****************9998777666 PP == domain 6 score: 4.8 bits; conditional E-value: 0.035 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002339-T1 234 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRV 269 7889***********************999999875 PP == domain 7 score: 1.0 bits; conditional E-value: 0.48 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l++ y + gd+++A+++ e+ +e ++ g FUN_002339-T1 274 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAIEVG 306 67789999***************9998777665 PP == domain 8 score: 3.5 bits; conditional E-value: 0.083 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + gd+++A+++ e+ ++ ++ gh FUN_002339-T1 314 AYGNLGNAYRSLGDFRKAIEYHEKHLKIAIEVGHR 348 7889********************99998888886 PP == domain 9 score: 1.9 bits; conditional E-value: 0.26 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l+ y + gd+++A+++ e+ +e ++ g FUN_002339-T1 354 AYGSLGTVYQSLGDFRKAIEYHEKHLEIAIEVG 386 6778999****************9998777666 PP == domain 10 score: 4.8 bits; conditional E-value: 0.035 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002339-T1 394 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRV 429 7889***********************999999875 PP == domain 11 score: 1.0 bits; conditional E-value: 0.48 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l++ y + gd+++A+++ e+ +e ++ g FUN_002339-T1 434 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAIEVG 466 67789999***************9998777665 PP == domain 12 score: 4.8 bits; conditional E-value: 0.035 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002339-T1 474 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRV 509 7889***********************999999875 PP == domain 13 score: 0.5 bits; conditional E-value: 0.71 RPN7 38 aledlaehyakigdlenAlkayerarekt 66 a+ l++ y + gd+++A+++ e+ +e + FUN_002339-T1 514 AYGSLGNAYDSLGDFRKAIEYHEKHLEIA 542 67789999**************9988765 PP == domain 14 score: 2.1 bits; conditional E-value: 0.22 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002339-T1 554 AYGNLGNAYQSLGDFRKAIEYHEKHLE 580 6889*****************999876 PP == domain 15 score: 3.7 bits; conditional E-value: 0.073 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + gd+++A+++ e+ ++ ++ gh FUN_002339-T1 594 AYGNLGNAYQSLGDFRKAIEYHEKHLKIAIEVGHR 628 6889********************99998888886 PP == domain 16 score: 1.5 bits; conditional E-value: 0.35 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l+ y + gd+++A+++ e+ +e ++ g FUN_002339-T1 634 AYGSLGTVYRSLGDFRKAIEYHEKHLEIAIEVG 666 5778999****************9998777666 PP == domain 17 score: 4.8 bits; conditional E-value: 0.035 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002339-T1 674 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRV 709 7889***********************999999875 PP == domain 18 score: 0.7 bits; conditional E-value: 0.61 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ l++ y + gd+++A+++ e+ +e ++ g FUN_002339-T1 714 AYGSLGNAYDSLGDFRKAIEYHEKQLEIAIEVG 746 67789999***************9988776665 PP == domain 19 score: 4.8 bits; conditional E-value: 0.032 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002339-T1 754 AYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEVGHRV 789 7889***********************999999875 PP == domain 20 score: 0.1 bits; conditional E-value: 0.91 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002339-T1 794 AYGSLGNAYDSLGDFRKAIEYHEKHLE 820 67789999*************999877 PP == domain 21 score: 2.6 bits; conditional E-value: 0.15 RPN7 37 raledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002339-T1 833 SAYGNLGNAYQSLGDFRKAIEYHEKHLE 860 68899*****************999876 PP == domain 22 score: 3.3 bits; conditional E-value: 0.099 RPN7 38 aledlaehyakigdlenAlkayerarektt 67 a+ +l++ y + gd+++A+++ e+ +e ++ FUN_002339-T1 874 AYGNLGNAYQTLGDFQKAIEYHEKHLEIAI 903 67899******************9888665 PP == domain 23 score: -0.9 bits; conditional E-value: 1.8 RPN7 39 ledlaehyakigdlenAlkayerar 63 + l++ y + gd+++A+++ e+ + FUN_002339-T1 915 YGSLGNAYRSLGDFRKAIEYHEKDL 939 6679999************999855 PP == domain 24 score: 2.5 bits; conditional E-value: 0.17 RPN7 38 aledlaehyakigdlenAlkayerarek 65 a+ +l++ y + gd+++A+++ e+ +e FUN_002339-T1 954 AYGNLGNAYQSLGDFRKAIEYHEKHLEI 981 7889******************998775 PP == domain 25 score: 2.7 bits; conditional E-value: 0.15 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliek 105 a+ l++ y + gd+++A+++ e+ +e + + + + ++gi+++ + k +e ++ ++ FUN_002339-T1 1034 AYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSDRVGEGSAYGNLGIAYQSMGEFRKAIEYHEKHLQI 1101 56677888888888888888888887777776666666666666666666666666655555555544 PP == domain 26 score: 0.5 bits; conditional E-value: 0.68 RPN7 39 ledlaehyakigdlenAlkayerarekttslgh 71 + +l+ y ++g++++A+++ e+ ++ ++ lg+ FUN_002339-T1 1075 YGNLGIAYQSMGEFRKAIEYHEKHLQIAIELGN 1107 566777778888888888888777666555554 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 0.54 4.6e+02 219 246 .. 76 103 .. 71 108 .. 0.88 2 ? 2.6 0.0 0.13 1.1e+02 219 246 .. 116 143 .. 106 150 .. 0.88 3 ? 2.0 0.0 0.19 1.7e+02 219 244 .. 156 181 .. 150 184 .. 0.88 4 ? -1.0 0.0 1.5 1.3e+03 219 243 .. 196 220 .. 192 223 .. 0.87 5 ? 0.5 0.0 0.54 4.6e+02 219 243 .. 236 260 .. 232 263 .. 0.88 6 ? 0.3 0.0 0.63 5.4e+02 219 243 .. 276 300 .. 272 303 .. 0.88 7 ? 1.4 0.0 0.3 2.5e+02 219 244 .. 316 341 .. 312 344 .. 0.89 8 ? -1.0 0.0 1.5 1.3e+03 219 243 .. 356 380 .. 352 383 .. 0.87 9 ? 0.5 0.0 0.54 4.6e+02 219 243 .. 396 420 .. 392 423 .. 0.88 10 ? 0.3 0.0 0.63 5.4e+02 219 243 .. 436 460 .. 432 463 .. 0.88 11 ? 0.5 0.0 0.54 4.6e+02 219 243 .. 476 500 .. 472 503 .. 0.88 12 ? 1.5 0.0 0.26 2.2e+02 219 246 .. 516 543 .. 512 547 .. 0.88 13 ? 2.4 0.0 0.14 1.2e+02 219 246 .. 556 583 .. 551 590 .. 0.88 14 ? 2.1 0.0 0.18 1.6e+02 219 244 .. 596 621 .. 585 624 .. 0.89 15 ? -1.3 0.0 2 1.7e+03 219 243 .. 636 660 .. 632 663 .. 0.86 16 ? 0.5 0.0 0.54 4.6e+02 219 243 .. 676 700 .. 672 703 .. 0.88 17 ? 0.5 0.0 0.53 4.5e+02 219 243 .. 716 740 .. 712 743 .. 0.88 18 ? 0.5 0.0 0.54 4.6e+02 219 243 .. 756 780 .. 752 783 .. 0.88 19 ? 1.6 0.0 0.25 2.1e+02 219 246 .. 796 823 .. 792 828 .. 0.88 20 ? 2.3 0.0 0.15 1.3e+02 219 246 .. 836 863 .. 830 866 .. 0.88 21 ? 2.0 0.0 0.19 1.6e+02 220 243 .. 877 900 .. 874 904 .. 0.88 22 ? -0.3 0.0 0.99 8.4e+02 219 242 .. 916 939 .. 914 948 .. 0.85 23 ? 2.3 0.0 0.15 1.3e+02 219 246 .. 956 983 .. 950 986 .. 0.88 24 ? -2.5 0.0 4.4 3.8e+03 220 242 .. 997 1019 .. 995 1023 .. 0.84 25 ? 1.6 0.0 0.24 2.1e+02 219 246 .. 1036 1063 .. 1031 1067 .. 0.88 26 ? -2.0 0.0 3.1 2.6e+03 220 243 .. 1077 1100 .. 1073 1102 .. 0.86 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 0.54 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 76 GNLGNAFQSLGDFRKAIEYHEKHLEIAK 103 56899*****************988766 PP == domain 2 score: 2.6 bits; conditional E-value: 0.13 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 116 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 143 67899*****************988766 PP == domain 3 score: 2.0 bits; conditional E-value: 0.19 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 156 GNLGNAYQSLGDFRKAIEYHEKHLKI 181 67899*****************9875 PP == domain 4 score: -1.0 bits; conditional E-value: 1.5 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + +++ + lg+ rkA +y +k+++ FUN_002339-T1 196 GSLGTVYQSLGDFRKAIEYHEKHLE 220 6789999*************99875 PP == domain 5 score: 0.5 bits; conditional E-value: 0.54 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 236 GNLGNAYRSLGDFRKAIEYHEKHLE 260 56899****************9875 PP == domain 6 score: 0.3 bits; conditional E-value: 0.63 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 276 GSLGNAYDSLGDFRKAIEYHEKHLE 300 67899****************9975 PP == domain 7 score: 1.4 bits; conditional E-value: 0.3 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 316 GNLGNAYRSLGDFRKAIEYHEKHLKI 341 56899*****************9875 PP == domain 8 score: -1.0 bits; conditional E-value: 1.5 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + +++ + lg+ rkA +y +k+++ FUN_002339-T1 356 GSLGTVYQSLGDFRKAIEYHEKHLE 380 6789999*************99875 PP == domain 9 score: 0.5 bits; conditional E-value: 0.54 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 396 GNLGNAYRSLGDFRKAIEYHEKHLE 420 56899****************9875 PP == domain 10 score: 0.3 bits; conditional E-value: 0.63 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 436 GSLGNAYDSLGDFRKAIEYHEKHLE 460 67899****************9975 PP == domain 11 score: 0.5 bits; conditional E-value: 0.54 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 476 GNLGNAYRSLGDFRKAIEYHEKHLE 500 56899****************9875 PP == domain 12 score: 1.5 bits; conditional E-value: 0.26 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 516 GSLGNAYDSLGDFRKAIEYHEKHLEIAK 543 67899*****************988765 PP == domain 13 score: 2.4 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 556 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 583 67899*****************988766 PP == domain 14 score: 2.1 bits; conditional E-value: 0.18 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 596 GNLGNAYQSLGDFRKAIEYHEKHLKI 621 67899*****************9875 PP == domain 15 score: -1.3 bits; conditional E-value: 2 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + +++ + lg+ rkA +y +k+++ FUN_002339-T1 636 GSLGTVYRSLGDFRKAIEYHEKHLE 660 678999999**********999875 PP == domain 16 score: 0.5 bits; conditional E-value: 0.54 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 676 GNLGNAYRSLGDFRKAIEYHEKHLE 700 56899****************9875 PP == domain 17 score: 0.5 bits; conditional E-value: 0.53 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 716 GSLGNAYDSLGDFRKAIEYHEKQLE 740 67899****************9976 PP == domain 18 score: 0.5 bits; conditional E-value: 0.54 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002339-T1 756 GNLGNAYRSLGDFRKAIEYHEKHLE 780 56899****************9875 PP == domain 19 score: 1.6 bits; conditional E-value: 0.25 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 796 GSLGNAYDSLGDFRKAIEYHEKHLEIAK 823 67899*****************988765 PP == domain 20 score: 2.3 bits; conditional E-value: 0.15 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 836 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 863 67899*****************998766 PP == domain 21 score: 2.0 bits; conditional E-value: 0.19 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ +lg+ +kA +y +k+++ FUN_002339-T1 877 NLGNAYQTLGDFQKAIEYHEKHLE 900 6899****************9976 PP == domain 22 score: -0.3 bits; conditional E-value: 0.99 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ lg+ rkA +y +k + FUN_002339-T1 916 GSLGNAYRSLGDFRKAIEYHEKDL 939 568999*************99865 PP == domain 23 score: 2.3 bits; conditional E-value: 0.15 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 956 GNLGNAYQSLGDFRKAIEYHEKHLEIAK 983 67899*****************998766 PP == domain 24 score: -2.5 bits; conditional E-value: 4.4 TPR_15 220 ayAaAllllgqnrkALpyfrkka 242 ++ A lg+ rkA +y +k + FUN_002339-T1 997 NLGNACQSLGDFRKAIEYHEKSL 1019 58899999**********99875 PP == domain 25 score: 1.6 bits; conditional E-value: 0.24 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002339-T1 1036 GSLGNAYDSLGDFRKAIEYHEKHLEIAK 1063 67899*****************988765 PP == domain 26 score: -2.0 bits; conditional E-value: 3.1 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ +g+ rkA +y +k+++ FUN_002339-T1 1077 NLGIAYQSMGEFRKAIEYHEKHLQ 1100 67889***************9876 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.9 0.0 0.82 7e+02 3 20 .. 114 131 .. 112 133 .. 0.89 2 ? 1.9 0.0 0.82 7e+02 3 20 .. 154 171 .. 152 173 .. 0.89 3 ? -1.1 0.0 7.4 6.3e+03 3 20 .. 194 211 .. 192 212 .. 0.86 4 ? 0.5 0.0 2.3 2e+03 3 20 .. 234 251 .. 232 252 .. 0.89 5 ? 0.5 0.0 2.3 2e+03 3 20 .. 314 331 .. 312 332 .. 0.89 6 ? -1.1 0.0 7.4 6.3e+03 3 20 .. 354 371 .. 352 372 .. 0.86 7 ? 0.5 0.0 2.3 2e+03 3 20 .. 394 411 .. 392 412 .. 0.89 8 ? 0.5 0.0 2.3 2e+03 3 20 .. 474 491 .. 472 492 .. 0.89 9 ? 1.9 0.0 0.82 7e+02 3 20 .. 554 571 .. 552 573 .. 0.89 10 ? 1.9 0.0 0.82 7e+02 3 20 .. 594 611 .. 592 613 .. 0.89 11 ? 0.5 0.0 2.3 2e+03 3 20 .. 674 691 .. 672 692 .. 0.89 12 ? 0.5 0.0 2.3 2e+03 3 20 .. 754 771 .. 752 772 .. 0.89 13 ? 1.9 0.0 0.82 7e+02 3 20 .. 834 851 .. 832 853 .. 0.89 14 ? 3.2 0.0 0.31 2.6e+02 3 20 .. 874 891 .. 872 893 .. 0.89 15 ? -1.4 0.0 9.4 8e+03 3 20 .. 914 931 .. 913 932 .. 0.85 16 ? 1.9 0.0 0.82 7e+02 3 20 .. 954 971 .. 952 973 .. 0.89 17 ? 0.8 0.0 1.8 1.5e+03 3 20 .. 994 1011 .. 992 1013 .. 0.89 Alignments for each domain: == domain 1 score: 1.9 bits; conditional E-value: 0.82 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 114 AYGNLGNAYQSLGDFRKA 131 789***********9887 PP == domain 2 score: 1.9 bits; conditional E-value: 0.82 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 154 AYGNLGNAYQSLGDFRKA 171 789***********9887 PP == domain 3 score: -1.1 bits; conditional E-value: 7.4 TPR_4 3 allaLArallalGdldeA 20 a+ L+ +++ lGd+ A FUN_002339-T1 194 AYGSLGTVYQSLGDFRKA 211 67789*********9877 PP == domain 4 score: 0.5 bits; conditional E-value: 2.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002339-T1 234 AYGNLGNAYRSLGDFRKA 251 6789**********9877 PP == domain 5 score: 0.5 bits; conditional E-value: 2.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002339-T1 314 AYGNLGNAYRSLGDFRKA 331 6789**********9877 PP == domain 6 score: -1.1 bits; conditional E-value: 7.4 TPR_4 3 allaLArallalGdldeA 20 a+ L+ +++ lGd+ A FUN_002339-T1 354 AYGSLGTVYQSLGDFRKA 371 67789*********9877 PP == domain 7 score: 0.5 bits; conditional E-value: 2.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002339-T1 394 AYGNLGNAYRSLGDFRKA 411 6789**********9877 PP == domain 8 score: 0.5 bits; conditional E-value: 2.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002339-T1 474 AYGNLGNAYRSLGDFRKA 491 6789**********9877 PP == domain 9 score: 1.9 bits; conditional E-value: 0.82 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 554 AYGNLGNAYQSLGDFRKA 571 789***********9887 PP == domain 10 score: 1.9 bits; conditional E-value: 0.82 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 594 AYGNLGNAYQSLGDFRKA 611 789***********9887 PP == domain 11 score: 0.5 bits; conditional E-value: 2.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002339-T1 674 AYGNLGNAYRSLGDFRKA 691 6789**********9877 PP == domain 12 score: 0.5 bits; conditional E-value: 2.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002339-T1 754 AYGNLGNAYRSLGDFRKA 771 6789**********9877 PP == domain 13 score: 1.9 bits; conditional E-value: 0.82 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 834 AYGNLGNAYQSLGDFRKA 851 789***********9887 PP == domain 14 score: 3.2 bits; conditional E-value: 0.31 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 874 AYGNLGNAYQTLGDFQKA 891 7889**********9887 PP == domain 15 score: -1.4 bits; conditional E-value: 9.4 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a+ lGd+ A FUN_002339-T1 914 AYGSLGNAYRSLGDFRKA 931 566799********9877 PP == domain 16 score: 1.9 bits; conditional E-value: 0.82 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 954 AYGNLGNAYQSLGDFRKA 971 789***********9887 PP == domain 17 score: 0.8 bits; conditional E-value: 1.8 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002339-T1 994 AYGNLGNACQSLGDFRKA 1011 7889**********9887 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.8 0.1 0.013 11 102 174 .. 75 145 .. 47 181 .. 0.57 2 ! 6.2 0.1 0.0098 8.3 100 171 .. 113 182 .. 90 222 .. 0.73 3 ? 0.2 0.0 0.66 5.7e+02 104 170 .. 197 261 .. 187 270 .. 0.53 4 ? 1.5 0.0 0.26 2.2e+02 100 171 .. 233 302 .. 207 311 .. 0.74 5 ? 0.4 0.0 0.57 4.9e+02 102 170 .. 315 381 .. 296 395 .. 0.61 6 ? 0.5 0.0 0.53 4.5e+02 102 170 .. 355 421 .. 321 425 .. 0.57 7 ? 1.2 0.0 0.34 2.9e+02 100 171 .. 393 462 .. 376 469 .. 0.74 8 ? 2.3 0.0 0.16 1.3e+02 100 172 .. 473 543 .. 447 548 .. 0.77 9 ! 6.2 0.1 0.0098 8.3 100 171 .. 553 622 .. 531 661 .. 0.74 10 ? 0.2 0.0 0.69 5.8e+02 102 170 .. 635 701 .. 627 706 .. 0.61 11 ? 1.6 0.0 0.25 2.2e+02 100 171 .. 673 742 .. 647 748 .. 0.74 12 ? 1.9 0.0 0.2 1.7e+02 100 172 .. 753 823 .. 737 827 .. 0.77 13 ? 4.3 0.1 0.037 31 93 170 .. 833 901 .. 813 906 .. 0.52 14 ? 3.5 0.0 0.067 57 76 116 .. 856 896 .. 835 952 .. 0.62 15 ? 3.4 0.0 0.07 60 102 173 .. 915 984 .. 909 988 .. 0.87 16 ? 5.7 0.0 0.014 12 102 208 .. 995 1097 .. 986 1115 .. 0.70 Alignments for each domain: == domain 1 score: 5.8 bits; conditional E-value: 0.013 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyena 174 y lG+ + lg +a++ ++ Lei + D ++++ +L + y+ g f++a +++++ lei ++ FUN_002339-T1 75 YGNLGNAFQSLGDFRKAIEYHEKHLEIAKEV--SDRFGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV 145 5566666666666666666666666665555..3445555566666666666666666666666666665543 PP == domain 2 score: 6.2 bits; conditional E-value: 0.0098 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 + y lG+ + lg +a++ ++ Lei + D + ++++ +L + y+ g f++a +++++ l+i FUN_002339-T1 113 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLKIA 182 467777888888888888888888888887776..5677778888899999999999999999999998885 PP == domain 3 score: 0.2 bits; conditional E-value: 0.66 TPR_NPHP3 104 alGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 +lG + lg +a++ ++ Lei + + ++++ +L + y g f++a +++++ lei FUN_002339-T1 197 SLGTVYQSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEI 261 44444444444444444444444443222..122223445555666666666666666666665555 PP == domain 4 score: 1.5 bits; conditional E-value: 0.26 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqaleiy 171 + y lG+ + lg +a++ ++ Lei ++ h + ++++ L + y+ g f++a +++++ lei FUN_002339-T1 233 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIA---IEVGHRVgEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 302 568888888888888888888888888874...4445655235677788888888888888888888888875 PP == domain 5 score: 0.4 bits; conditional E-value: 0.57 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlv.arslhqLagLyaqwgkfstaealykqalei 170 y lG+ + lg +a++ ++ L i a++ h + ++++ L ++y+ g f++a +++++ lei FUN_002339-T1 315 YGNLGNAYRSLGDFRKAIEYHEKHLKI---AIEVGHRVGeGSAYGSLGTVYQSLGDFRKAIEYHEKHLEI 381 444555555555555555555555444...2333444331344556777777777777777777777766 PP == domain 6 score: 0.5 bits; conditional E-value: 0.53 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 y +lG + lg +a++ ++ Lei + + ++++ +L + y g f++a +++++ lei FUN_002339-T1 355 YGSLGTVYQSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEI 421 4444444444444444444444444443222..122223445555556666666666666666555555 PP == domain 7 score: 1.2 bits; conditional E-value: 0.34 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqaleiy 171 + y lG+ + lg +a++ ++ Lei ++ h + ++++ L + y+ g f++a +++++ lei FUN_002339-T1 393 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIA---IEVGHRVgEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIA 462 567788888888888888888888888774...4445654235677788888888888888888888888775 PP == domain 8 score: 2.3 bits; conditional E-value: 0.16 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqaleiye 172 + y lG+ + lg +a++ ++ Lei ++ h + ++++ L + y+ g f++a +++++ lei + FUN_002339-T1 473 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIA---IEVGHRVgEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAK 543 678888888888888888888888888874...45566552467788899999999999999999999999876 PP == domain 9 score: 6.2 bits; conditional E-value: 0.0098 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 + y lG+ + lg +a++ ++ Lei + D + ++++ +L + y+ g f++a +++++ l+i FUN_002339-T1 553 SAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKHLKIA 622 456666666666666677777778888887766..5677778888899999999999999999999988885 PP == domain 10 score: 0.2 bits; conditional E-value: 0.69 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 y +lG + lg +a++ ++ Lei + + ++++ +L + y g f++a +++++ lei FUN_002339-T1 635 YGSLGTVYRSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLEI 701 6667777777777777777777777765443..223333455566666666666666666666666665 PP == domain 11 score: 1.6 bits; conditional E-value: 0.25 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqaleiy 171 + y lG+ + lg +a++ ++ Lei ++ h + ++++ L + y+ g f++a +++++ lei FUN_002339-T1 673 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIA---IEVGHRVgEGNAYGSLGNAYDSLGDFRKAIEYHEKQLEIA 742 568888888888888888888888888874...4445655235677788888888888888888888888875 PP == domain 12 score: 1.9 bits; conditional E-value: 0.2 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqaleiye 172 + y lG+ + lg +a++ ++ Lei ++ h + ++++ L + y+ g f++a +++++ lei + FUN_002339-T1 753 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIA---IEVGHRVgEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAK 823 568888888888888888888888888874...45566552467788899999999999999999999998876 PP == domain 13 score: 4.3 bits; conditional E-value: 0.037 TPR_NPHP3 93 ltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 + y lG+ + lg +a++ ++ Lei + D + ++ +L + y++ g f++a +++++ lei FUN_002339-T1 833 SA-------YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGGAYGNLGNAYQTLGDFQKAIEYHEKHLEI 901 33.......4444444444444444555555555555444..344444555666666666666666666666666655 PP == domain 14 score: 3.5 bits; conditional E-value: 0.067 TPR_NPHP3 76 kaYlnaikkledavegeltlakvadlyealGrflkdlglls 116 +++l+ +k++ d v++ ++ + y++lG f k + + FUN_002339-T1 856 EKHLEIAKEVSDRVGEGGAYGNLGNAYQTLGDFQKAIEYHE 896 44556666666666666666666666666666666554433 PP == domain 15 score: 3.4 bits; conditional E-value: 0.07 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 y +lG+ + lg +a++ ++ Lei + D+ ++++ +L + y+ g f++a +++++ lei ++ FUN_002339-T1 915 YGSLGNAYRSLGDFRKAIEYHEKDLEIAIEV--SDQVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKE 984 8899999999999999999999999998666..5777778899999999999******99999999999875 PP == domain 16 score: 5.7 bits; conditional E-value: 0.014 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyqk 195 y lG+ ++ lg +a++ +++Lei + D ++++ L + y+ g f++a +++++ lei ++ sd + + l + yq FUN_002339-T1 995 YGNLGNACQSLGDFRKAIEYHEKSLEIAIEV--SDRVGEGNAYGSLGNAYDSLGDFRKAIEYHEKHLEIAKKV--SDRVGEGSAYGNLGIAYQS 1084 7778888888888888888888888887665..4666677888888888999999999988888888888765..3444444445555555555 PP TPR_NPHP3 196 qdkhdlaeplkkr 208 + + a +++ FUN_002339-T1 1085 MGEFRKAIEYHEK 1097 5555555555444 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 6.2 5.3e+03 15 28 .. 8 21 .. 7 24 .. 0.86 2 ? -1.0 0.2 3.2 2.7e+03 14 27 .. 47 60 .. 39 66 .. 0.78 3 ? 2.2 0.0 0.32 2.8e+02 5 30 .. 78 103 .. 76 109 .. 0.86 4 ? 3.3 0.0 0.15 1.3e+02 5 30 .. 118 143 .. 116 148 .. 0.88 5 ? 3.6 0.1 0.12 1e+02 5 28 .. 158 181 .. 156 189 .. 0.90 6 ? -0.8 0.0 2.7 2.3e+03 6 27 .. 199 220 .. 196 224 .. 0.79 7 ? 1.2 0.0 0.64 5.5e+02 5 27 .. 238 260 .. 236 265 .. 0.87 8 ? 0.4 0.0 1.2 1e+03 5 27 .. 278 300 .. 276 305 .. 0.85 9 ? 2.4 0.0 0.27 2.3e+02 5 28 .. 318 341 .. 316 349 .. 0.89 10 ? -0.8 0.0 2.7 2.3e+03 6 27 .. 359 380 .. 356 384 .. 0.79 11 ? 1.2 0.0 0.64 5.5e+02 5 27 .. 398 420 .. 396 425 .. 0.87 12 ? 0.4 0.0 1.2 1e+03 5 27 .. 438 460 .. 436 465 .. 0.85 13 ? 1.2 0.0 0.64 5.5e+02 5 27 .. 478 500 .. 476 505 .. 0.87 14 ? 1.2 0.0 0.67 5.7e+02 5 30 .. 518 543 .. 516 546 .. 0.85 15 ? 3.3 0.0 0.15 1.3e+02 5 30 .. 558 583 .. 556 588 .. 0.88 16 ? 3.6 0.1 0.12 1e+02 5 28 .. 598 621 .. 596 629 .. 0.90 17 ? -1.5 0.0 4.4 3.8e+03 13 27 .. 646 660 .. 636 664 .. 0.76 18 ? 1.2 0.0 0.64 5.5e+02 5 27 .. 678 700 .. 676 705 .. 0.87 19 ? 0.5 0.0 1.1 9.2e+02 5 27 .. 718 740 .. 716 745 .. 0.85 20 ? 1.2 0.0 0.64 5.5e+02 5 27 .. 758 780 .. 756 785 .. 0.87 21 ? 1.4 0.0 0.56 4.8e+02 5 30 .. 798 823 .. 796 828 .. 0.85 22 ? 3.3 0.0 0.15 1.3e+02 5 30 .. 838 863 .. 836 868 .. 0.88 23 ? 2.8 0.1 0.2 1.7e+02 5 27 .. 878 900 .. 876 905 .. 0.88 24 ? 0.6 0.0 0.99 8.4e+02 5 27 .. 918 940 .. 916 946 .. 0.86 25 ? 3.7 0.0 0.11 98 5 31 .. 958 984 .. 956 989 .. 0.87 26 ? 1.3 0.0 0.61 5.2e+02 5 28 .. 998 1021 .. 996 1026 .. 0.86 27 ? 1.4 0.0 0.56 4.8e+02 5 30 .. 1038 1063 .. 1036 1068 .. 0.85 28 ? 1.3 0.0 0.59 5.1e+02 5 28 .. 1078 1101 .. 1076 1129 .. 0.91 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 6.2 ARM_TT21_4th 15 YkkAinYYeaalks 28 ++kAi+Y e+ lk+ FUN_002339-T1 8 FRKAIEYHEKHLKI 21 79*******99987 PP == domain 2 score: -1.0 bits; conditional E-value: 3.2 ARM_TT21_4th 14 qYkkAinYYeaalk 27 +++kAi+Y e+ l+ FUN_002339-T1 47 DFRKAIKYHEKHLE 60 799******99876 PP == domain 3 score: 2.2 bits; conditional E-value: 0.32 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 78 LGNAFQSLGDFRKAIEYHEKHLEIAK 103 799999999**********9988765 PP == domain 4 score: 3.3 bits; conditional E-value: 0.15 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 118 LGNAYQSLGDFRKAIEYHEKHLEIAK 143 799****************9988765 PP == domain 5 score: 3.6 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ lk+ FUN_002339-T1 158 LGNAYQSLGDFRKAIEYHEKHLKI 181 799****************99986 PP == domain 6 score: -0.8 bits; conditional E-value: 2.7 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G+ + +++kAi+Y e+ l+ FUN_002339-T1 199 GTVYQSLGDFRKAIEYHEKHLE 220 6666677789******998776 PP == domain 7 score: 1.2 bits; conditional E-value: 0.64 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 238 LGNAYRSLGDFRKAIEYHEKHLE 260 799999999*********99876 PP == domain 8 score: 0.4 bits; conditional E-value: 1.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 278 LGNAYDSLGDFRKAIEYHEKHLE 300 6888888899********99876 PP == domain 9 score: 2.4 bits; conditional E-value: 0.27 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ lk+ FUN_002339-T1 318 LGNAYRSLGDFRKAIEYHEKHLKI 341 799999999**********99986 PP == domain 10 score: -0.8 bits; conditional E-value: 2.7 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G+ + +++kAi+Y e+ l+ FUN_002339-T1 359 GTVYQSLGDFRKAIEYHEKHLE 380 6666677789******998776 PP == domain 11 score: 1.2 bits; conditional E-value: 0.64 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 398 LGNAYRSLGDFRKAIEYHEKHLE 420 799999999*********99876 PP == domain 12 score: 0.4 bits; conditional E-value: 1.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 438 LGNAYDSLGDFRKAIEYHEKHLE 460 6888888899********99876 PP == domain 13 score: 1.2 bits; conditional E-value: 0.64 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 478 LGNAYRSLGDFRKAIEYHEKHLE 500 799999999*********99876 PP == domain 14 score: 1.2 bits; conditional E-value: 0.67 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 518 LGNAYDSLGDFRKAIEYHEKHLEIAK 543 6888888999*********9988765 PP == domain 15 score: 3.3 bits; conditional E-value: 0.15 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 558 LGNAYQSLGDFRKAIEYHEKHLEIAK 583 799****************9988765 PP == domain 16 score: 3.6 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ lk+ FUN_002339-T1 598 LGNAYQSLGDFRKAIEYHEKHLKI 621 799****************99986 PP == domain 17 score: -1.5 bits; conditional E-value: 4.4 ARM_TT21_4th 13 HqYkkAinYYeaalk 27 +++kAi+Y e+ l+ FUN_002339-T1 646 GDFRKAIEYHEKHLE 660 5799*****998776 PP == domain 18 score: 1.2 bits; conditional E-value: 0.64 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 678 LGNAYRSLGDFRKAIEYHEKHLE 700 799999999*********99876 PP == domain 19 score: 0.5 bits; conditional E-value: 1.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 718 LGNAYDSLGDFRKAIEYHEKQLE 740 6888888899********99876 PP == domain 20 score: 1.2 bits; conditional E-value: 0.64 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 758 LGNAYRSLGDFRKAIEYHEKHLE 780 799999999*********99876 PP == domain 21 score: 1.4 bits; conditional E-value: 0.56 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 798 LGNAYDSLGDFRKAIEYHEKHLEIAK 823 6888888999*********9988765 PP == domain 22 score: 3.3 bits; conditional E-value: 0.15 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 838 LGNAYQSLGDFRKAIEYHEKHLEIAK 863 799****************9988765 PP == domain 23 score: 2.8 bits; conditional E-value: 0.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 878 LGNAYQTLGDFQKAIEYHEKHLE 900 799***************99876 PP == domain 24 score: 0.6 bits; conditional E-value: 0.99 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002339-T1 918 LGNAYRSLGDFRKAIEYHEKDLE 940 699999999*********98765 PP == domain 25 score: 3.7 bits; conditional E-value: 0.11 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksseq 31 +G+a+ +++kAi+Y e+ l++ ++ FUN_002339-T1 958 LGNAYQSLGDFRKAIEYHEKHLEIAKE 984 799****************99987765 PP == domain 26 score: 1.3 bits; conditional E-value: 0.61 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ l++ FUN_002339-T1 998 LGNACQSLGDFRKAIEYHEKSLEI 1021 6899999999*********98875 PP == domain 27 score: 1.4 bits; conditional E-value: 0.56 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002339-T1 1038 LGNAYDSLGDFRKAIEYHEKHLEIAK 1063 6888888999*********9988765 PP == domain 28 score: 1.3 bits; conditional E-value: 0.59 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G a+ +++kAi+Y e+ l++ FUN_002339-T1 1078 LGIAYQSMGEFRKAIEYHEKHLQI 1101 688999999**********98875 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 5.4 0.1 0.0095 8.1 71 142 .. 99 178 .. 92 187 .. 0.68 2 ? 0.8 0.0 0.24 2.1e+02 87 141 .. 195 257 .. 177 267 .. 0.61 3 ? 2.9 0.2 0.053 45 87 149 .. 282 345 .. 271 457 .. 0.58 4 ? 2.2 0.1 0.087 74 85 142 .. 440 498 .. 395 509 .. 0.77 5 ! 6.4 0.2 0.0048 4.1 86 146 .. 521 582 .. 511 698 .. 0.67 6 ? 3.4 0.2 0.04 34 180 180 .. 699 699 .. 576 781 .. 0.40 7 ! 6.9 0.4 0.0033 2.8 85 142 .. 800 858 .. 710 898 .. 0.73 8 ! 7.6 0.5 0.002 1.7 85 247 .. 800 974 .. 793 978 .. 0.58 9 ? 4.6 0.0 0.017 14 84 143 .. 959 1019 .. 916 1031 .. 0.71 10 ? 4.0 0.0 0.025 22 85 141 .. 1040 1097 .. 1021 1105 .. 0.88 11 ? -0.1 0.0 0.45 3.8e+02 410 450 .. 1119 1159 .. 1111 1163 .. 0.87 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.0095 TPR_IF140-IFT172 71 Lglldeaekllksckrydllnklyqasgkwdkale.......vaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 L++ +e + + + + y l + yq+ g + ka+e +a++ +dr+ ++y n + ++ gd+++ai+++ek FUN_002339-T1 99 LEIAKEVSDRFGEGSAYGNLGNAYQSLGDFRKAIEyhekhleIAKEvSDRVVEGSAYGNLGNAYQSLGDFRKAIEYHEKH 178 56666666666666666666666666666666554111111166543799999999999999999999999999999985 PP == domain 2 score: 0.8 bits; conditional E-value: 0.24 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaekk........drihlrktyynyakhleakgdieeaiklyek 141 y l +yq+ g + ka+e ek+ +r+ ++y n + + gd+++ai+++ek FUN_002339-T1 195 YGSLGTVYQSLGDFRKAIEYHEKHleiaievgNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEK 257 555555555555555555544443222222236666667777777777777777777777776 PP == domain 3 score: 2.9 bits; conditional E-value: 0.053 TPR_IF140-IFT172 87 ydllnklyqasgkwdkaleva.ekkdrihlrktyynyakhleakgdieeaiklyeksethrfev 149 yd l ++ +a + +k le+a e +r+ ++y n + + gd+++ai+++ek ev FUN_002339-T1 282 YDSLGDFRKAIEYHEKHLEIAiEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKHLKIAIEV 345 6666666666666666666662334566666666666666666666666666666544433333 PP == domain 4 score: 2.2 bits; conditional E-value: 0.087 TPR_IF140-IFT172 85 krydllnklyqasgkwdkaleva.ekkdrihlrktyynyakhleakgdieeaiklyeks 142 + yd l ++ +a + +k le+a e +r+ ++y n + + gd+++ai+++ek FUN_002339-T1 440 NAYDSLGDFRKAIEYHEKHLEIAiEVGNRVGEGNAYGNLGNAYRSLGDFRKAIEYHEKH 498 57888888888888888888888344688888888888888888888888888888875 PP == domain 5 score: 6.4 bits; conditional E-value: 0.0048 TPR_IF140-IFT172 86 rydllnklyqasgkwdkalevaekk.drihlrktyynyakhleakgdieeaiklyeksethr 146 yd l ++ +a + +k le+a+k dr+ ++y n + ++ gd+++ai+++ek FUN_002339-T1 521 AYDSLGDFRKAIEYHEKHLEIAKKVgDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIA 582 56777777777777777777776533677777777777777777777777777666643333 PP == domain 6 score: 3.4 bits; conditional E-value: 0.04 TPR_IF140-IFT172 180 l 180 l FUN_002339-T1 699 L 699 3 PP == domain 7 score: 6.9 bits; conditional E-value: 0.0033 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 + yd l ++ +a + +k le+a+k +dr+ ++y n + ++ gd+++ai+++ek FUN_002339-T1 800 NAYDSLGDFRKAIEYHEKHLEIAKKvSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKH 858 56777777777777777777777653577777777777777777777777777777764 PP == domain 8 score: 7.6 bits; conditional E-value: 0.002 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aL.esyvkkskdkelk 173 + yd l ++ +a + +k le+a+k +dr+ ++y n + ++ gd+++ai+++ek ev + + + +L ++y + + ++ FUN_002339-T1 800 NAYDSLGDFRKAIEYHEKHLEIAKKvSDRVGEGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGGAygNLgNAYQTLGDFQKAI 892 569999999999999999999998646999999999999999999999999999999876666666544444322113412344433334444 PP TPR_IF140-IFT172 174 kWwaqylestgel....etalkyyeaaedylslv..r..vlCyledlekaaelanetgdkaacyhlarqyenadeikeaihf 247 + ++le + e+ + y + + y sl r + + +dle a e++++ g+ +a l+ y++ +++++ai++ FUN_002339-T1 893 EYHEKHLEIAIEVgdrvGEGGAYGSLGNAYRSLGdfRkaIEYHEKDLEIAIEVSDQVGEGSAYGNLGNAYQSLGDFRKAIEY 974 4445554444333100023333333344444443112113334445666666666666666666666666666666666666 PP == domain 9 score: 4.6 bits; conditional E-value: 0.017 TPR_IF140-IFT172 84 ckrydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyekse 143 + y+ l ++ +a + +k le+a++ + r+ +y n + +++ gd+++ai+++eks FUN_002339-T1 959 GNAYQSLGDFRKAIEYHEKHLEIAKEvSARVGEGGAYGNLGNACQSLGDFRKAIEYHEKSL 1019 3456666667777777777777776525688888889999999999999999999999885 PP == domain 10 score: 4.0 bits; conditional E-value: 0.025 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyek 141 + yd l ++ +a + +k le+a+k +dr+ ++y n ++ g++++ai+++ek FUN_002339-T1 1040 NAYDSLGDFRKAIEYHEKHLEIAKKvSDRVGEGSAYGNLGIAYQSMGEFRKAIEYHEK 1097 6799999999999999999999987479999999999999999999999999999987 PP == domain 11 score: -0.1 bits; conditional E-value: 0.45 TPR_IF140-IFT172 410 aevclkqenyhlatkkftqaGdkvkamkaLlksGdtekiif 450 ++ ++ +++++a kf a + ++ ++++lks d ki f FUN_002339-T1 1119 GNGFFSLGQFEIALDKFVSAVEAFNTLRSFLKSEDDWKINF 1159 555667789*************************9998865 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 2.7 2.3e+03 9 24 .. 41 56 .. 35 57 .. 0.80 2 ? 0.4 0.0 1.6 1.4e+03 3 24 .. 75 96 .. 74 97 .. 0.84 3 ? 2.8 0.0 0.28 2.4e+02 2 24 .. 114 136 .. 113 137 .. 0.88 4 ? 2.8 0.0 0.28 2.4e+02 2 24 .. 154 176 .. 153 177 .. 0.88 5 ? 1.5 0.0 0.76 6.5e+02 2 24 .. 194 216 .. 193 217 .. 0.88 6 ? 3.6 0.0 0.16 1.4e+02 3 24 .. 235 256 .. 234 257 .. 0.88 7 ? -0.7 0.0 3.8 3.2e+03 3 24 .. 275 296 .. 274 297 .. 0.80 8 ? 3.6 0.0 0.16 1.4e+02 3 24 .. 315 336 .. 314 337 .. 0.88 9 ? 1.5 0.0 0.76 6.5e+02 2 24 .. 354 376 .. 353 377 .. 0.88 10 ? 3.6 0.0 0.16 1.4e+02 3 24 .. 395 416 .. 394 417 .. 0.88 11 ? -0.7 0.0 3.8 3.2e+03 3 24 .. 435 456 .. 434 457 .. 0.80 12 ? 3.6 0.0 0.16 1.4e+02 3 24 .. 475 496 .. 474 497 .. 0.88 13 ? -0.7 0.0 3.8 3.2e+03 3 24 .. 515 536 .. 514 537 .. 0.80 14 ? 2.8 0.0 0.28 2.4e+02 2 24 .. 554 576 .. 553 577 .. 0.88 15 ? 2.8 0.0 0.28 2.4e+02 2 24 .. 594 616 .. 593 617 .. 0.88 16 ? 2.8 0.0 0.29 2.5e+02 2 24 .. 634 656 .. 633 657 .. 0.89 17 ? 3.6 0.0 0.16 1.4e+02 3 24 .. 675 696 .. 674 697 .. 0.88 18 ? -0.7 0.0 3.8 3.2e+03 3 24 .. 715 736 .. 714 737 .. 0.80 19 ? 3.6 0.0 0.16 1.4e+02 3 24 .. 755 776 .. 754 777 .. 0.88 20 ? -0.7 0.0 3.8 3.2e+03 3 24 .. 795 816 .. 794 817 .. 0.80 21 ? 2.8 0.0 0.28 2.4e+02 2 24 .. 834 856 .. 833 857 .. 0.88 22 ? -0.3 0.0 2.7 2.3e+03 3 24 .. 875 896 .. 874 897 .. 0.84 23 ? 5.5 0.0 0.039 33 2 24 .. 914 936 .. 913 937 .. 0.91 24 ? 2.8 0.0 0.28 2.4e+02 2 24 .. 954 976 .. 953 977 .. 0.88 25 ? 1.8 0.0 0.59 5e+02 3 25 .. 995 1017 .. 994 1021 .. 0.86 26 ? -0.7 0.0 3.8 3.2e+03 3 24 .. 1035 1056 .. 1034 1057 .. 0.80 27 ? -0.6 0.0 3.5 3e+03 3 24 .. 1075 1096 .. 1073 1097 .. 0.80 28 ? -0.6 0.0 3.3 2.9e+03 2 20 .. 1166 1184 .. 1165 1185 .. 0.88 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 2.7 PPR 9 gycknGkleeAlelfk 24 ++ ++G++++A+++++ FUN_002339-T1 41 AFQSHGDFRKAIKYHE 56 67789*******9987 PP == domain 2 score: 0.4 bits; conditional E-value: 1.6 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +++ + G++++A+e+++ FUN_002339-T1 75 YGNLGNAFQSLGDFRKAIEYHE 96 66777899999********987 PP == domain 3 score: 2.8 bits; conditional E-value: 0.28 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002339-T1 114 AYGNLGNAYQSLGDFRKAIEYHE 136 6888999*************987 PP == domain 4 score: 2.8 bits; conditional E-value: 0.28 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002339-T1 154 AYGNLGNAYQSLGDFRKAIEYHE 176 6888999*************987 PP == domain 5 score: 1.5 bits; conditional E-value: 0.76 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl +y + G++++A+e+++ FUN_002339-T1 194 AYGSLGTVYQSLGDFRKAIEYHE 216 6889999999**********987 PP == domain 6 score: 3.6 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002339-T1 235 YGNLGNAYRSLGDFRKAIEYHE 256 778889*************987 PP == domain 7 score: -0.7 bits; conditional E-value: 3.8 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002339-T1 275 YGSLGNAYDSLGDFRKAIEYHE 296 67777777789*******9987 PP == domain 8 score: 3.6 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002339-T1 315 YGNLGNAYRSLGDFRKAIEYHE 336 778889*************987 PP == domain 9 score: 1.5 bits; conditional E-value: 0.76 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl +y + G++++A+e+++ FUN_002339-T1 354 AYGSLGTVYQSLGDFRKAIEYHE 376 6889999999**********987 PP == domain 10 score: 3.6 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002339-T1 395 YGNLGNAYRSLGDFRKAIEYHE 416 778889*************987 PP == domain 11 score: -0.7 bits; conditional E-value: 3.8 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002339-T1 435 YGSLGNAYDSLGDFRKAIEYHE 456 67777777789*******9987 PP == domain 12 score: 3.6 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002339-T1 475 YGNLGNAYRSLGDFRKAIEYHE 496 778889*************987 PP == domain 13 score: -0.7 bits; conditional E-value: 3.8 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002339-T1 515 YGSLGNAYDSLGDFRKAIEYHE 536 67777777789*******9987 PP == domain 14 score: 2.8 bits; conditional E-value: 0.28 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002339-T1 554 AYGNLGNAYQSLGDFRKAIEYHE 576 6888999*************987 PP == domain 15 score: 2.8 bits; conditional E-value: 0.28 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002339-T1 594 AYGNLGNAYQSLGDFRKAIEYHE 616 6888999*************987 PP == domain 16 score: 2.8 bits; conditional E-value: 0.29 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl +y + G++++A+e+++ FUN_002339-T1 634 AYGSLGTVYRSLGDFRKAIEYHE 656 6999999*************987 PP == domain 17 score: 3.6 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002339-T1 675 YGNLGNAYRSLGDFRKAIEYHE 696 778889*************987 PP == domain 18 score: -0.7 bits; conditional E-value: 3.8 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002339-T1 715 YGSLGNAYDSLGDFRKAIEYHE 736 67777777789*******9987 PP == domain 19 score: 3.6 bits; conditional E-value: 0.16 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002339-T1 755 YGNLGNAYRSLGDFRKAIEYHE 776 778889*************987 PP == domain 20 score: -0.7 bits; conditional E-value: 3.8 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002339-T1 795 YGSLGNAYDSLGDFRKAIEYHE 816 67777777789*******9987 PP == domain 21 score: 2.8 bits; conditional E-value: 0.28 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002339-T1 834 AYGNLGNAYQSLGDFRKAIEYHE 856 6888999*************987 PP == domain 22 score: -0.3 bits; conditional E-value: 2.7 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y G++++A+e+++ FUN_002339-T1 875 YGNLGNAYQTLGDFQKAIEYHE 896 66777899999*******9987 PP == domain 23 score: 5.5 bits; conditional E-value: 0.039 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002339-T1 914 AYGSLGNAYRSLGDFRKAIEYHE 936 599999**************987 PP == domain 24 score: 2.8 bits; conditional E-value: 0.28 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002339-T1 954 AYGNLGNAYQSLGDFRKAIEYHE 976 6888999*************987 PP == domain 25 score: 1.8 bits; conditional E-value: 0.59 PPR 3 ynslIsgycknGkleeAlelfke 25 y l +++ + G++++A+e++++ FUN_002339-T1 995 YGNLGNACQSLGDFRKAIEYHEK 1017 777889999**********9987 PP == domain 26 score: -0.7 bits; conditional E-value: 3.8 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002339-T1 1035 YGSLGNAYDSLGDFRKAIEYHE 1056 67777777789*******9987 PP == domain 27 score: -0.6 bits; conditional E-value: 3.5 PPR 3 ynslIsgycknGkleeAlelfk 24 y l +y + G++++A+e+++ FUN_002339-T1 1075 YGNLGIAYQSMGEFRKAIEYHE 1096 56666689999*******9987 PP == domain 28 score: -0.6 bits; conditional E-value: 3.3 PPR 2 tynslIsgycknGkleeAl 20 +y ++ +++ + Gk++eAl FUN_002339-T1 1166 SYCAMWRSLLRIGKIDEAL 1184 6888889999********7 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.0 1.2 1e+03 5 46 .. 46 93 .. 43 109 .. 0.68 2 ? 5.1 0.0 0.049 42 5 47 .. 86 134 .. 82 150 .. 0.88 3 ? 4.6 0.0 0.068 58 5 46 .. 126 173 .. 122 180 .. 0.91 4 ? 2.3 0.0 0.36 3.1e+02 5 46 .. 206 253 .. 202 262 .. 0.74 5 ? 2.0 0.0 0.45 3.9e+02 5 46 .. 286 333 .. 284 340 .. 0.73 6 ? 2.3 0.0 0.36 3.1e+02 5 46 .. 366 413 .. 362 422 .. 0.74 7 ? -1.0 0.0 4 3.4e+03 27 46 .. 434 453 .. 430 462 .. 0.75 8 ? 2.1 0.0 0.41 3.5e+02 5 46 .. 446 493 .. 444 502 .. 0.72 9 ? 4.6 0.0 0.067 57 5 47 .. 526 574 .. 524 589 .. 0.87 10 ? 4.4 0.0 0.079 67 5 46 .. 566 613 .. 564 620 .. 0.91 11 ? 2.5 0.0 0.31 2.6e+02 5 46 .. 646 693 .. 642 702 .. 0.74 12 ? 3.3 0.0 0.17 1.5e+02 5 46 .. 726 773 .. 724 782 .. 0.80 13 ? -0.5 0.0 2.7 2.3e+03 27 47 .. 794 814 .. 790 831 .. 0.72 14 ? 4.7 0.0 0.064 55 5 47 .. 806 854 .. 804 869 .. 0.87 15 ? 5.1 0.1 0.046 39 5 46 .. 846 893 .. 842 902 .. 0.90 16 ? 3.2 0.1 0.19 1.6e+02 5 47 .. 926 974 .. 922 989 .. 0.76 17 ? 3.1 0.0 0.2 1.7e+02 5 46 .. 966 1013 .. 962 1022 .. 0.87 18 ? 2.9 0.0 0.23 1.9e+02 5 47 .. 1006 1054 .. 1003 1067 .. 0.78 19 ? 2.8 0.0 0.25 2.1e+02 5 46 .. 1046 1093 .. 1044 1099 .. 0.89 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 1.2 TPR_19 5 gdydeAlalLeqalae..dPd....naearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + + a+ +L++a lg++ +A++ FUN_002339-T1 46 GDFRKAIKYHEKHLEIaiEAGhrvgEGNAYGNLGNAFQSLGDFRKAIE 93 777777777777444422222344477888888888888888888876 PP == domain 2 score: 5.1 bits; conditional E-value: 0.049 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 86 GDFRKAIEYHEKHLEIAKEvsdrfgEGSAYGNLGNAYQSLGDFRKAIEY 134 9999999999999999888888999999******************985 PP == domain 3 score: 4.6 bits; conditional E-value: 0.068 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 126 GDFRKAIEYHEKHLEIAKEvsdrvvEGSAYGNLGNAYQSLGDFRKAIE 173 9999999999999999999888999999999***************87 PP == domain 4 score: 2.3 bits; conditional E-value: 0.36 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 206 GDFRKAIEYHEKHLEIAIEvgnrvgEGNAYGNLGNAYRSLGDFRKAIE 253 777777777777555522222334488999999*********999987 PP == domain 5 score: 2.0 bits; conditional E-value: 0.45 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 286 GDFRKAIEYHEKHLEIAIEvgnrvgEGNAYGNLGNAYRSLGDFRKAIE 333 67777777777755552222233448899999***********99987 PP == domain 6 score: 2.3 bits; conditional E-value: 0.36 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 366 GDFRKAIEYHEKHLEIAIEvgnrvgEGNAYGNLGNAYRSLGDFRKAIE 413 777777777777555522222334488999999*********999987 PP == domain 7 score: -1.0 bits; conditional E-value: 4 TPR_19 27 arllLArallalgrldeAea 46 a+ L++a+ lg++ +A++ FUN_002339-T1 434 AYGSLGNAYDSLGDFRKAIE 453 56668888888888888876 PP == domain 8 score: 2.1 bits; conditional E-value: 0.41 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 446 GDFRKAIEYHEKHLEIAIEvgnrvgEGNAYGNLGNAYRSLGDFRKAIE 493 6777777777775555222223344888999999********999987 PP == domain 9 score: 4.6 bits; conditional E-value: 0.067 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 526 GDFRKAIEYHEKHLEIAKKvgdrvgEGSAYGNLGNAYQSLGDFRKAIEY 574 89999999999999998888888889999*****************985 PP == domain 10 score: 4.4 bits; conditional E-value: 0.079 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 566 GDFRKAIEYHEKHLEIAKEvsdrvvEGSAYGNLGNAYQSLGDFRKAIE 613 9999999999999999999888999999999***************87 PP == domain 11 score: 2.5 bits; conditional E-value: 0.31 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 646 GDFRKAIEYHEKHLEIAIEvgnrvgEGNAYGNLGNAYRSLGDFRKAIE 693 78888888888866553333333558899999***********99987 PP == domain 12 score: 3.3 bits; conditional E-value: 0.17 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 726 GDFRKAIEYHEKQLEIAIEvgnrvgEGNAYGNLGNAYRSLGDFRKAIE 773 88999999999988884444444559999****************987 PP == domain 13 score: -0.5 bits; conditional E-value: 2.7 TPR_19 27 arllLArallalgrldeAeal 47 a+ L++a+ lg++ +A++ FUN_002339-T1 794 AYGSLGNAYDSLGDFRKAIEY 814 556677888888888888765 PP == domain 14 score: 4.7 bits; conditional E-value: 0.064 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 806 GDFRKAIEYHEKHLEIAKKvsdrvgEGSAYGNLGNAYQSLGDFRKAIEY 854 899999999999999988888888899999****************985 PP == domain 15 score: 5.1 bits; conditional E-value: 0.046 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 846 GDFRKAIEYHEKHLEIAKEvsdrvgEGGAYGNLGNAYQTLGDFQKAIE 893 9999999999999999888888999999******************87 PP == domain 16 score: 3.2 bits; conditional E-value: 0.19 TPR_19 5 gdydeAlalLeq....alaedPd..naearllLArallalgrldeAeal 47 gd+ +A+++ e+ a++ + + a+ +L++a+ lg++ +A++ FUN_002339-T1 926 GDFRKAIEYHEKdleiAIEVSDQvgEGSAYGNLGNAYQSLGDFRKAIEY 974 7777777777776666555555566888999***************985 PP == domain 17 score: 3.1 bits; conditional E-value: 0.2 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002339-T1 966 GDFRKAIEYHEKHLEIAKEvsarvgEGGAYGNLGNACQSLGDFRKAIE 1013 899999999999999988888888899999999999999999999987 PP == domain 18 score: 2.9 bits; conditional E-value: 0.23 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002339-T1 1006 GDFRKAIEYHEKSLEIAIEvsdrvgEGNAYGSLGNAYDSLGDFRKAIEY 1054 8999999999998888333333455999999999999999999999875 PP == domain 19 score: 2.8 bits; conditional E-value: 0.25 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L+ a+ +g++ +A++ FUN_002339-T1 1046 GDFRKAIEYHEKHLEIAKKvsdrvgEGSAYGNLGIAYQSMGEFRKAIE 1093 8999999999999999888888888999999**************987 PP >> Sec1 Sec1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.0 0.0 0.037 31 304 339 .. 76 111 .. 48 149 .. 0.61 2 ? 2.3 0.1 0.12 1e+02 300 337 .. 112 149 .. 90 187 .. 0.74 3 ? -2.8 0.0 4.3 3.6e+03 301 333 .. 233 265 .. 200 277 .. 0.65 4 ? -3.4 0.0 6.2 5.3e+03 305 338 .. 277 310 .. 249 322 .. 0.83 5 ? -2.8 0.0 4.2 3.6e+03 303 337 .. 315 349 .. 289 384 .. 0.74 6 ? 3.0 0.0 0.074 63 284 337 .. 533 589 .. 518 629 .. 0.75 7 ? -3.4 0.0 6.3 5.4e+03 301 333 .. 673 705 .. 644 711 .. 0.70 8 ? 0.7 0.0 0.36 3e+02 306 339 .. 798 831 .. 767 864 .. 0.72 9 ? 4.3 0.0 0.031 26 284 339 .. 813 871 .. 807 904 .. 0.73 10 ? 1.5 0.0 0.21 1.8e+02 303 339 .. 955 991 .. 927 1027 .. 0.82 11 ? 0.1 0.0 0.56 4.7e+02 304 339 .. 1036 1071 .. 1008 1101 .. 0.85 Alignments for each domain: == domain 1 score: 4.0 bits; conditional E-value: 0.037 Sec1 304 adlkdfvekLpelqeekkklslHtnlaeellkiikk 339 +l ++ ++L+++++ + ++H+++a e+++++ + FUN_002339-T1 76 GNLGNAFQSLGDFRKAIEYHEKHLEIAKEVSDRFGE 111 566777778888888888888888888888877765 PP == domain 2 score: 2.3 bits; conditional E-value: 0.12 Sec1 300 sesiadlkdfvekLpelqeekkklslHtnlaeellkii 337 + +l ++ ++L+++++ + ++H+++a e+++++ FUN_002339-T1 112 GSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRV 149 4566788999999********************99887 PP == domain 3 score: -2.8 bits; conditional E-value: 4.3 Sec1 301 esiadlkdfvekLpelqeekkklslHtnlaeel 333 + +l ++ ++L+++++ + ++H+++a e+ FUN_002339-T1 233 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 265 445566777777888888888888888877665 PP == domain 4 score: -3.4 bits; conditional E-value: 6.2 Sec1 305 dlkdfvekLpelqeekkklslHtnlaeellkiik 338 l ++ ++L+++++ + ++H+++a e+ +++ FUN_002339-T1 277 SLGNAYDSLGDFRKAIEYHEKHLEIAIEVGNRVG 310 57788899******************99877765 PP == domain 5 score: -2.8 bits; conditional E-value: 4.2 Sec1 303 iadlkdfvekLpelqeekkklslHtnlaeellkii 337 +l ++ ++L+++++ + ++H+++a e+ +++ FUN_002339-T1 315 YGNLGNAYRSLGDFRKAIEYHEKHLKIAIEVGHRV 349 56778888999999999999999999998776555 PP == domain 6 score: 3.0 bits; conditional E-value: 0.074 Sec1 284 elkaknaelkrk.gaks....sesiadlkdfvekLpelqeekkklslHtnlaeellkii 337 e+ +k+ e+ +k g + + +l ++ ++L+++++ + ++H+++a e+++++ FUN_002339-T1 533 EYHEKHLEIAKKvG--DrvgeGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRV 589 55555544444322..23465667788999999*********************99887 PP == domain 7 score: -3.4 bits; conditional E-value: 6.3 Sec1 301 esiadlkdfvekLpelqeekkklslHtnlaeel 333 + +l ++ ++L+++++ + ++H+++a e+ FUN_002339-T1 673 NAYGNLGNAYRSLGDFRKAIEYHEKHLEIAIEV 705 455677788889999999999999999998665 PP == domain 8 score: 0.7 bits; conditional E-value: 0.36 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ ++L+++++ + ++H+++a ++++++ + FUN_002339-T1 798 LGNAYDSLGDFRKAIEYHEKHLEIAKKVSDRVGE 831 6677778888888888888888888888888765 PP == domain 9 score: 4.3 bits; conditional E-value: 0.031 Sec1 284 elkaknaelkrkgaks....sesiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 e+ +k+ e+ +k +++ + +l ++ ++L+++++ + ++H+++a e+++++ + FUN_002339-T1 813 EYHEKHLEIAKK-VSDrvgeGSAYGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGE 871 555555444443.333456567788999****************************9987 PP == domain 10 score: 1.5 bits; conditional E-value: 0.21 Sec1 303 iadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 +l ++ ++L+++++ + ++H+++a e++ ++ + FUN_002339-T1 955 YGNLGNAYQSLGDFRKAIEYHEKHLEIAKEVSARVGE 991 56788999***********************998876 PP == domain 11 score: 0.1 bits; conditional E-value: 0.56 Sec1 304 adlkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ ++L+++++ + ++H+++a ++++++ + FUN_002339-T1 1036 GSLGNAYDSLGDFRKAIEYHEKHLEIAKKVSDRVGE 1071 567788999*********************999875 PP >> NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 2.3 1.9e+03 64 89 .. 47 70 .. 11 110 .. 0.78 2 ? -1.7 0.0 5.4 4.6e+03 70 89 .. 171 190 .. 162 205 .. 0.86 3 ? -2.0 0.0 6.7 5.7e+03 66 89 .. 249 270 .. 218 276 .. 0.85 4 ? -1.4 0.0 4.3 3.7e+03 70 89 .. 331 350 .. 310 378 .. 0.86 5 ? -2.3 0.0 8.1 6.9e+03 70 89 .. 411 430 .. 390 433 .. 0.86 6 ? -2.1 0.0 7.1 6.1e+03 70 89 .. 491 510 .. 468 517 .. 0.85 7 ? -1.8 0.0 5.8 5e+03 70 89 .. 611 630 .. 597 638 .. 0.86 8 ? -2.1 0.0 7 6e+03 67 89 .. 690 710 .. 666 717 .. 0.85 9 ? -2.2 0.0 7.4 6.3e+03 70 89 .. 771 790 .. 750 797 .. 0.86 10 ? 3.7 0.0 0.12 99 70 89 .. 931 950 .. 922 985 .. 0.82 11 ? -1.0 0.0 3.4 2.9e+03 70 94 .. 1091 1115 .. 1079 1129 .. 0.81 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 2.3 NAD_binding_11 64 dfepgFaidlllKDlglaldlarelg 89 df + ai+++ K l++a+++++++g FUN_002339-T1 47 DFRK--AIKYHEKHLEIAIEAGHRVG 70 4444..68888899999998888876 PP == domain 2 score: -1.7 bits; conditional E-value: 5.4 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002339-T1 171 AIEYHEKHLKIAIEVGHRVG 190 799*************9987 PP == domain 3 score: -2.0 bits; conditional E-value: 6.7 NAD_binding_11 66 epgFaidlllKDlglaldlarelg 89 + ai+++ K l++a+++++++g FUN_002339-T1 249 RK--AIEYHEKHLEIAIEVGHRVG 270 44..7999***********99986 PP == domain 4 score: -1.4 bits; conditional E-value: 4.3 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002339-T1 331 AIEYHEKHLKIAIEVGHRVG 350 799*************9987 PP == domain 5 score: -2.3 bits; conditional E-value: 8.1 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002339-T1 411 AIEYHEKHLEIAIEVGHRVG 430 799************99986 PP == domain 6 score: -2.1 bits; conditional E-value: 7.1 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002339-T1 491 AIEYHEKHLEIAIEVGHRVG 510 799************99986 PP == domain 7 score: -1.8 bits; conditional E-value: 5.8 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002339-T1 611 AIEYHEKHLKIAIEVGHRVG 630 799************99987 PP == domain 8 score: -2.1 bits; conditional E-value: 7 NAD_binding_11 67 pgFaidlllKDlglaldlarelg 89 + ai+++ K l++a+++++++g FUN_002339-T1 690 K--AIEYHEKHLEIAIEVGHRVG 710 3..799************99986 PP == domain 9 score: -2.2 bits; conditional E-value: 7.4 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ K l++a+++++++g FUN_002339-T1 771 AIEYHEKHLEIAIEVGHRVG 790 799************99986 PP == domain 10 score: 3.7 bits; conditional E-value: 0.12 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ KDl++a+++ +++g FUN_002339-T1 931 AIEYHEKDLEIAIEVSDQVG 950 799************99987 PP == domain 11 score: -1.0 bits; conditional E-value: 3.4 NAD_binding_11 70 aidlllKDlglaldlarelgvplpl 94 ai+++ K l++a++l++++g + FUN_002339-T1 1091 AIEYHEKHLQIAIELGNRAGEGMSH 1115 799**************99977665 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.11 93 74 107 .. 97 132 .. 68 134 .. 0.87 2 ? 1.1 0.1 0.76 6.5e+02 75 106 .. 180 211 .. 135 214 .. 0.67 3 ? -1.8 0.0 6.1 5.2e+03 86 106 .. 231 251 .. 217 254 .. 0.59 4 ? 0.7 0.0 1 8.5e+02 75 107 .. 260 292 .. 248 294 .. 0.79 5 ? -1.9 0.0 6.4 5.4e+03 87 106 .. 312 331 .. 299 341 .. 0.65 6 ? 0.5 0.0 1.2 9.9e+02 76 107 .. 341 372 .. 328 374 .. 0.79 7 ? -1.8 0.0 6.1 5.2e+03 86 106 .. 391 411 .. 377 414 .. 0.59 8 ? 0.7 0.0 1 8.5e+02 75 107 .. 420 452 .. 408 454 .. 0.79 9 ? -1.8 0.0 6.1 5.2e+03 86 106 .. 471 491 .. 457 494 .. 0.59 10 ? 0.8 0.0 0.94 8e+02 75 107 .. 500 532 .. 486 534 .. 0.79 11 ? 0.4 0.0 1.2 1e+03 75 107 .. 540 572 .. 531 574 .. 0.79 12 ? -0.8 0.0 2.9 2.5e+03 75 107 .. 580 612 .. 573 614 .. 0.80 13 ? 0.5 0.0 1.2 1e+03 76 107 .. 621 652 .. 604 654 .. 0.77 14 ? -1.8 0.0 6.1 5.2e+03 86 106 .. 671 691 .. 657 694 .. 0.59 15 ? 0.7 0.0 1 8.5e+02 75 107 .. 700 732 .. 688 734 .. 0.79 16 ? -1.7 0.0 5.6 4.8e+03 84 106 .. 749 771 .. 736 774 .. 0.59 17 ? 0.8 0.0 0.95 8.1e+02 75 107 .. 780 812 .. 767 816 .. 0.80 18 ? 1.9 0.0 0.43 3.7e+02 75 107 .. 820 852 .. 810 854 .. 0.85 19 ? 0.4 0.1 1.2 1.1e+03 75 106 .. 900 931 .. 859 934 .. 0.69 20 ? 1.9 0.1 0.42 3.6e+02 75 106 .. 980 1011 .. 933 1014 .. 0.72 21 ? 2.0 0.0 0.39 3.3e+02 75 107 .. 1020 1052 .. 1013 1054 .. 0.86 22 ? 1.1 0.0 0.77 6.5e+02 51 92 .. 1522 1563 .. 1516 1574 .. 0.74 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.11 GGDEF_2 74 e..ellerlrrrlggitvriGvGrpveglaglrrSy 107 + e+++++++r+g+ +++ +G+++++l ++r++ FUN_002339-T1 97 KhlEIAKEVSDRFGEGSAYGNLGNAYQSLGDFRKAI 132 145899***************************986 PP == domain 2 score: 1.1 bits; conditional E-value: 0.76 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 +++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 180 KIAIEVGHRVGEGSAYGSLGTVYQSLGDFRKA 211 44445555555666667777777777777776 PP == domain 3 score: -1.8 bits; conditional E-value: 6.1 GGDEF_2 86 gitvriGvGrpveglaglrrS 106 + +++ +G+++++l ++r++ FUN_002339-T1 231 EGNAYGNLGNAYRSLGDFRKA 251 334444456666666666665 PP == domain 4 score: 0.7 bits; conditional E-value: 1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 260 EIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAI 292 556667777778889999999999999999985 PP == domain 5 score: -1.9 bits; conditional E-value: 6.4 GGDEF_2 87 itvriGvGrpveglaglrrS 106 +++ +G+++++l ++r++ FUN_002339-T1 312 GNAYGNLGNAYRSLGDFRKA 331 34444456666666666665 PP == domain 6 score: 0.5 bits; conditional E-value: 1.2 GGDEF_2 76 llerlrrrlggitvriGvGrpveglaglrrSy 107 ++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 341 IAIEVGHRVGEGSAYGSLGTVYQSLGDFRKAI 372 5556667777788899999********99985 PP == domain 7 score: -1.8 bits; conditional E-value: 6.1 GGDEF_2 86 gitvriGvGrpveglaglrrS 106 + +++ +G+++++l ++r++ FUN_002339-T1 391 EGNAYGNLGNAYRSLGDFRKA 411 334444456666666666665 PP == domain 8 score: 0.7 bits; conditional E-value: 1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 420 EIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAI 452 556667777778889999999999999999985 PP == domain 9 score: -1.8 bits; conditional E-value: 6.1 GGDEF_2 86 gitvriGvGrpveglaglrrS 106 + +++ +G+++++l ++r++ FUN_002339-T1 471 EGNAYGNLGNAYRSLGDFRKA 491 334444456666666666665 PP == domain 10 score: 0.8 bits; conditional E-value: 0.94 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 500 EIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAI 532 566667777788889999999999999999985 PP == domain 11 score: 0.4 bits; conditional E-value: 1.2 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 540 EIAKKVGDRVGEGSAYGNLGNAYQSLGDFRKAI 572 678888888888888888999999999999875 PP == domain 12 score: -0.8 bits; conditional E-value: 2.9 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+ + +++ +G+++++l ++r++ FUN_002339-T1 580 EIAKEVSDRVVEGSAYGNLGNAYQSLGDFRKAI 612 677777777777888888999*******99985 PP == domain 13 score: 0.5 bits; conditional E-value: 1.2 GGDEF_2 76 llerlrrrlggitvriGvGrpveglaglrrSy 107 ++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 621 IAIEVGHRVGEGSAYGSLGTVYRSLGDFRKAI 652 55566667777788888999999999999875 PP == domain 14 score: -1.8 bits; conditional E-value: 6.1 GGDEF_2 86 gitvriGvGrpveglaglrrS 106 + +++ +G+++++l ++r++ FUN_002339-T1 671 EGNAYGNLGNAYRSLGDFRKA 691 334444456666666666665 PP == domain 15 score: 0.7 bits; conditional E-value: 1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 700 EIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAI 732 556667777778889999999999999999985 PP == domain 16 score: -1.7 bits; conditional E-value: 5.6 GGDEF_2 84 lggitvriGvGrpveglaglrrS 106 +g+ +++ +G+++++l ++r++ FUN_002339-T1 749 VGEGNAYGNLGNAYRSLGDFRKA 771 44444444466666666666665 PP == domain 17 score: 0.8 bits; conditional E-value: 0.95 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002339-T1 780 EIAIEVGHRVGEGNAYGSLGNAYDSLGDFRKAI 812 566667777788889999999999999999985 PP == domain 18 score: 1.9 bits; conditional E-value: 0.43 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002339-T1 820 EIAKKVSDRVGEGSAYGNLGNAYQSLGDFRKAI 852 899999999999999999***********9985 PP == domain 19 score: 0.4 bits; conditional E-value: 1.2 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e++ ++ +r+g+ ++ +G+++++l ++r++ FUN_002339-T1 900 EIAIEVGDRVGEGGAYGSLGNAYRSLGDFRKA 931 45555556666666677777777777777776 PP == domain 20 score: 1.9 bits; conditional E-value: 0.42 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e+++++++r+g+ ++ +G+++++l ++r++ FUN_002339-T1 980 EIAKEVSARVGEGGAYGNLGNACQSLGDFRKA 1011 67777777777777777777777777777776 PP == domain 21 score: 2.0 bits; conditional E-value: 0.39 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++++r+g+ +++ +G+++++l ++r++ FUN_002339-T1 1020 EIAIEVSDRVGEGNAYGSLGNAYDSLGDFRKAI 1052 677789999999999***************986 PP == domain 22 score: 1.1 bits; conditional E-value: 0.77 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvriG 92 +l+a ++ lv+l++ ddea + e+++r+ r+l++ t++++ FUN_002339-T1 1522 AFLAAGARSVLVALWAIDDEA-TMEFMKRFYRHLKEgKTASAA 1563 56777788899********85.468888888888885444444 PP >> TPR_11 TPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.1 0.47 4e+02 30 42 .] 74 86 .. 73 93 .. 0.73 2 ? 3.1 0.1 0.13 1.1e+02 30 42 .] 114 126 .. 113 133 .. 0.75 3 ? 3.1 0.1 0.13 1.1e+02 30 42 .] 154 166 .. 153 173 .. 0.75 4 ? -2.4 0.0 6.8 5.7e+03 35 42 .] 199 206 .. 193 214 .. 0.52 5 ? 5.4 0.1 0.025 21 1 15 [. 239 253 .. 239 257 .. 0.96 6 ? 0.1 0.2 1.1 9.2e+02 1 15 [. 279 293 .. 272 297 .. 0.71 7 ? 5.4 0.1 0.025 21 1 15 [. 319 333 .. 319 337 .. 0.96 8 ? -2.4 0.0 6.8 5.7e+03 35 42 .] 359 366 .. 353 374 .. 0.52 9 ? 5.4 0.1 0.025 21 1 15 [. 399 413 .. 399 417 .. 0.96 10 ? 0.1 0.2 1.1 9.2e+02 1 15 [. 439 453 .. 432 457 .. 0.71 11 ? 5.4 0.1 0.025 21 1 15 [. 479 493 .. 479 497 .. 0.96 12 ? 0.1 0.2 1.1 9.2e+02 1 15 [. 519 533 .. 512 537 .. 0.71 13 ? 3.1 0.1 0.13 1.1e+02 30 42 .] 554 566 .. 553 573 .. 0.75 14 ? 3.1 0.1 0.13 1.1e+02 30 42 .] 594 606 .. 593 613 .. 0.75 15 ? 0.7 0.0 0.7 5.9e+02 1 15 [. 639 653 .. 639 657 .. 0.91 16 ? 5.4 0.1 0.025 21 1 15 [. 679 693 .. 679 697 .. 0.96 17 ? 0.4 0.2 0.93 7.9e+02 1 15 [. 719 733 .. 712 741 .. 0.67 18 ? 5.4 0.1 0.025 21 1 15 [. 759 773 .. 759 777 .. 0.96 19 ? 0.1 0.2 1.1 9.2e+02 1 15 [. 799 813 .. 792 817 .. 0.71 20 ? 3.1 0.1 0.13 1.1e+02 30 42 .] 834 846 .. 833 853 .. 0.75 21 ? 2.3 0.2 0.23 2e+02 30 42 .] 874 886 .. 873 893 .. 0.81 22 ? 5.4 0.1 0.025 21 1 15 [. 919 933 .. 919 937 .. 0.96 23 ? 3.1 0.1 0.13 1.1e+02 30 42 .] 954 966 .. 953 973 .. 0.75 24 ? -0.6 0.0 1.8 1.6e+03 1 16 [. 999 1014 .. 997 1021 .. 0.79 25 ? 0.1 0.2 1.1 9.2e+02 1 15 [. 1039 1053 .. 1032 1057 .. 0.71 26 ? 0.9 0.2 0.61 5.2e+02 30 42 .] 1074 1086 .. 1073 1086 .. 0.90 27 ? 1.4 0.0 0.44 3.7e+02 1 21 [. 1119 1139 .. 1119 1140 .. 0.87 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.47 TPR_11 30 ayynLGlayykqG 42 ay nLG+a++ +G FUN_002339-T1 74 AYGNLGNAFQSLG 86 6778888887776 PP == domain 2 score: 3.1 bits; conditional E-value: 0.13 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 114 AYGNLGNAYQSLG 126 6778888888776 PP == domain 3 score: 3.1 bits; conditional E-value: 0.13 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 154 AYGNLGNAYQSLG 166 6778888888776 PP == domain 4 score: -2.4 bits; conditional E-value: 6.8 TPR_11 35 GlayykqG 42 G +y+ +G FUN_002339-T1 199 GTVYQSLG 206 44444444 PP == domain 5 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 239 GNAYRSLGDFRKAIE 253 9*************7 PP == domain 6 score: 0.1 bits; conditional E-value: 1.1 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002339-T1 279 GNAYDSLGDFRKAIE 293 677777777777765 PP == domain 7 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 319 GNAYRSLGDFRKAIE 333 9*************7 PP == domain 8 score: -2.4 bits; conditional E-value: 6.8 TPR_11 35 GlayykqG 42 G +y+ +G FUN_002339-T1 359 GTVYQSLG 366 44444444 PP == domain 9 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 399 GNAYRSLGDFRKAIE 413 9*************7 PP == domain 10 score: 0.1 bits; conditional E-value: 1.1 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002339-T1 439 GNAYDSLGDFRKAIE 453 677777777777765 PP == domain 11 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 479 GNAYRSLGDFRKAIE 493 9*************7 PP == domain 12 score: 0.1 bits; conditional E-value: 1.1 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002339-T1 519 GNAYDSLGDFRKAIE 533 677777777777765 PP == domain 13 score: 3.1 bits; conditional E-value: 0.13 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 554 AYGNLGNAYQSLG 566 6778888888776 PP == domain 14 score: 3.1 bits; conditional E-value: 0.13 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 594 AYGNLGNAYQSLG 606 6778888888776 PP == domain 15 score: 0.7 bits; conditional E-value: 0.7 TPR_11 1 GdayyeqGkyeeAie 15 G +y+++G++ +Aie FUN_002339-T1 639 GTVYRSLGDFRKAIE 653 679**********97 PP == domain 16 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 679 GNAYRSLGDFRKAIE 693 9*************7 PP == domain 17 score: 0.4 bits; conditional E-value: 0.93 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002339-T1 719 GNAYDSLGDFRKAIE 733 666666666666665 PP == domain 18 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 759 GNAYRSLGDFRKAIE 773 9*************7 PP == domain 19 score: 0.1 bits; conditional E-value: 1.1 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002339-T1 799 GNAYDSLGDFRKAIE 813 677777777777765 PP == domain 20 score: 3.1 bits; conditional E-value: 0.13 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 834 AYGNLGNAYQSLG 846 6778888888776 PP == domain 21 score: 2.3 bits; conditional E-value: 0.23 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 874 AYGNLGNAYQTLG 886 6778999998877 PP == domain 22 score: 5.4 bits; conditional E-value: 0.025 TPR_11 1 GdayyeqGkyeeAie 15 G+ay+++G++ +Aie FUN_002339-T1 919 GNAYRSLGDFRKAIE 933 9*************7 PP == domain 23 score: 3.1 bits; conditional E-value: 0.13 TPR_11 30 ayynLGlayykqG 42 ay nLG+ay+ +G FUN_002339-T1 954 AYGNLGNAYQSLG 966 6778888888776 PP == domain 24 score: -0.6 bits; conditional E-value: 1.8 TPR_11 1 GdayyeqGkyeeAiea 16 G+a+ ++G++ +Aie FUN_002339-T1 999 GNACQSLGDFRKAIEY 1014 8999999999999985 PP == domain 25 score: 0.1 bits; conditional E-value: 1.1 TPR_11 1 GdayyeqGkyeeAie 15 G+ay ++G++ +Aie FUN_002339-T1 1039 GNAYDSLGDFRKAIE 1053 677777777777765 PP == domain 26 score: 0.9 bits; conditional E-value: 0.61 TPR_11 30 ayynLGlayykqG 42 ay nLG ay+ +G FUN_002339-T1 1074 AYGNLGIAYQSMG 1086 899*******998 PP == domain 27 score: 1.4 bits; conditional E-value: 0.44 TPR_11 1 GdayyeqGkyeeAieaYkkAl 21 G+ ++++G++e A+ ++ A+ FUN_002339-T1 1119 GNGFFSLGQFEIALDKFVSAV 1139 888**********99988776 PP >> CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.84 7.2e+02 11 22 .. 96 107 .. 94 108 .. 0.90 2 ? 1.1 0.0 0.84 7.2e+02 11 22 .. 136 147 .. 134 148 .. 0.90 3 ? 2.4 0.0 0.33 2.8e+02 11 22 .. 536 547 .. 534 548 .. 0.90 4 ? 1.1 0.0 0.84 7.2e+02 11 22 .. 576 587 .. 574 588 .. 0.90 5 ? 3.2 0.1 0.19 1.6e+02 11 22 .. 816 827 .. 814 828 .. 0.91 6 ? 1.1 0.0 0.84 7.2e+02 11 22 .. 856 867 .. 854 868 .. 0.90 7 ? -1.8 0.1 6.5 5.6e+03 11 20 .. 976 985 .. 975 986 .. 0.86 8 ? 3.2 0.1 0.19 1.6e+02 11 22 .. 1056 1067 .. 1054 1068 .. 0.91 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.84 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002339-T1 96 EKHLEIAKEVSD 107 89*******998 PP == domain 2 score: 1.1 bits; conditional E-value: 0.84 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002339-T1 136 EKHLEIAKEVSD 147 89*******998 PP == domain 3 score: 2.4 bits; conditional E-value: 0.33 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+++ D FUN_002339-T1 536 EKHLEIAKKVGD 547 89*******988 PP == domain 4 score: 1.1 bits; conditional E-value: 0.84 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002339-T1 576 EKHLEIAKEVSD 587 89*******998 PP == domain 5 score: 3.2 bits; conditional E-value: 0.19 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+++ D FUN_002339-T1 816 EKHLEIAKKVSD 827 89********99 PP == domain 6 score: 1.1 bits; conditional E-value: 0.84 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002339-T1 856 EKHLEIAKEVSD 867 89*******998 PP == domain 7 score: -1.8 bits; conditional E-value: 6.5 CaM_bdg_C0 11 qkklElARha 20 +k lE+A+ + FUN_002339-T1 976 EKHLEIAKEV 985 899****986 PP == domain 8 score: 3.2 bits; conditional E-value: 0.19 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+++ D FUN_002339-T1 1056 EKHLEIAKKVSD 1067 89********99 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1605 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 424 (0.0165982); expected 510.9 (0.02) Passed bias filter: 381 (0.0149149); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 35 (0.00137013); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 30 [number of targets reported over threshold] # CPU time: 0.67u 0.42s 00:00:01.09 Elapsed: 00:00:00.52 # Mc/sec: 12492.89 // Query: FUN_002340-T1 [L=236] Description: FUN_002340 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.6e-28 97.6 0.1 3.1e-26 92.7 0.1 2.1 1 Proteasome Proteasome subunit 1.2e-07 31.5 1.2 2e-07 30.8 1.2 1.3 1 Pr_beta_C Proteasome beta subunits C terminal ------ inclusion threshold ------ 0.013 16.0 0.0 0.017 15.6 0.0 1.2 1 DUF6144 Family of unknown function (DUF6144) Domain annotation for each model (and alignments): >> Proteasome Proteasome subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 92.7 0.1 3.6e-30 3.1e-26 27 189 .] 36 181 .. 33 181 .. 0.93 Alignments for each domain: == domain 1 score: 92.7 bits; conditional E-value: 3.6e-30 Proteasome 27 gskllskdtveKifkiddhigvafaGlaaDartlvdyaraeaqlyrlrygepisvelvkrvaaklqaytqrsgrrpfgvslliagvdeegkprLyq 122 g++++++++++Ki+ i ++i+++ aG+aaD++++++++++++ql++l++g++ ++ +a +++++ + ++++++ ++l+++gvd +g p L FUN_002340-T1 36 GDTIVADKNCSKIHYIAPNIYCCGAGTAADTEYVTQLISSNIQLHSLSTGRQARIV----TALRMLKQRLFRYQGYISAALVLGGVDLNG-PTL-- 124 577889999***********************************************....9999999999999**************655.555.. PP Proteasome 123 idpsGsvieykdavaiGsgsqaaygvlekeykedltleeavelakkalkealerdklsgknievavi 189 + + +G+gs aa++v+e+++k+d++l+ea +l+++a+ + + +d sg+++++++i FUN_002340-T1 125 --------HIQ--CTVGYGSLAATSVFESRCKPDMELDEAQKLVRDAIAAGIFNDLGSGSGVDLCII 181 ........444..679*************************************************97 PP >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.8 1.2 2.3e-11 2e-07 1 35 [. 195 230 .. 195 230 .. 0.98 Alignments for each domain: == domain 1 score: 30.8 bits; conditional E-value: 2.3e-11 Pr_beta_C 1 PNergeRqgsYkfkrGTTAVLkekV.plklevveev 35 +N +g Rqg+Y + r TTAV ++++ p+ ++v+e++ FUN_002340-T1 195 ANDKGVRQGRYSYIRKTTAVVTKDIkPIVVDVTETT 230 8*********************************97 PP >> DUF6144 Family of unknown function (DUF6144) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 1.9e-06 0.017 69 165 .. 57 157 .. 19 168 .. 0.79 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 1.9e-06 DUF6144 69 qcgygmdeklalvkelvessssleefassdkaka.aglsykegelylqfaf.cpcpmladvdrletntwcqcttgyskvlfekafe..cevdvell 160 cg g + v +l++s +l +++ +a+ + l + + l+ + +l vd qct+gy + fe c+ d+el FUN_002340-T1 57 CCGAGTAADTEYVTQLISSNIQLHSLSTGRQARIvTALRMLKQRLFRYQGYiSAALVLGGVDLNGPTLHIQCTVGYGSLAATSVFEsrCKPDMELD 152 4899**********************99999986256888888888655550556678888877777789*******9999999965599999998 PP DUF6144 161 ksikm 165 + k FUN_002340-T1 153 EAQKL 157 77765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (236 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 540 (0.0211392); expected 510.9 (0.02) Passed bias filter: 476 (0.0186338); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.30u 0.34s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2424.47 // Query: FUN_002341-T1 [L=1342] Description: FUN_002341 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-173 562.8 48.7 2.9e-19 69.5 0.5 12.1 11 TPR_12 Tetratricopeptide repeat 1.3e-164 521.0 36.2 4.1e-08 33.2 0.0 22.4 22 TPR_7 Tetratricopeptide repeat 5.7e-141 453.7 117.6 2.4e-08 33.9 1.4 22.5 22 TPR_1 Tetratricopeptide repeat 3.8e-99 322.7 29.4 9.6e-05 22.7 0.0 22.0 22 TPR_10 Tetratricopeptide repeat 9.7e-84 269.0 99.9 1.4e-05 25.4 0.8 22.4 22 TPR_8 Tetratricopeptide repeat 1.5e-65 212.5 103.7 1.4e-05 25.3 0.5 22.8 23 TPR_2 Tetratricopeptide repeat 8.7e-52 176.8 0.0 1.3e-51 176.2 0.0 1.2 1 CHAT CHAT domain 4.5e-34 113.9 26.9 4.3 8.8 0.0 21.6 21 TPR_14 Tetratricopeptide repeat 2.1e-29 101.9 48.8 0.22 12.1 0.1 19.2 21 Rapsyn_N Rapsyn N-terminal myristoylation a 1.6e-24 87.3 0.3 2.9e-05 24.0 0.1 7.2 9 TPR_MalT MalT-like TPR region 2.1e-17 62.3 43.1 2.3 9.2 0.1 16.8 14 TPR_17 Tetratricopeptide repeat 1.3e-15 57.4 25.7 81 4.7 0.0 18.5 17 TPR_6 Tetratricopeptide repeat 8.8e-15 55.0 0.6 2.4e+02 2.4 0.0 16.7 19 DUF2977 Protein of unknown function (DUF29 2.8e-14 53.4 18.1 4.9 7.7 0.0 15.1 16 TPR_9 Tetratricopeptide repeat 4e-13 50.4 35.1 4.1 8.1 0.0 18.6 20 ARM_TT21_4th Tetratricopeptide repeat protein 2 1.1e-11 45.4 28.0 0.53 11.3 0.4 15.4 15 TPR_16 Tetratricopeptide repeat 1e-10 41.9 6.9 2.4 8.0 0.1 9.2 11 TPR_NPHP3 Nephrocystin-3 TPR domain 2.4e-10 40.8 12.8 27 4.6 0.0 15.5 20 TPR_15 Tetratricopeptide repeat 2.4e-10 40.9 4.5 37 5.1 0.0 11.9 17 WH_Halo_primase Halobacteria primase winged helix 5.6e-10 40.0 2.9 58 4.2 0.0 12.6 14 ARM_CUL7_CUL9 CUL7/CUL9 ARM repeat domain 1.1e-09 37.9 14.3 0.4 9.7 0.3 9.0 9 TPR_IF140-IFT172 IF140/IFT172 TPR domain 7.2e-09 36.0 17.5 0.05 13.6 0.1 6.0 8 SNAP Soluble NSF attachment protein, SN 1.4e-08 35.5 17.8 8.2 7.2 0.0 12.9 14 GGDEF_2 GGDEF-like domain 1.5e-08 34.9 4.2 4.8e+02 2.4 0.0 12.4 11 TPR_4 Tetratricopeptide repeat 6.8e-08 32.7 45.0 27 5.8 0.1 19.2 20 PPR PPR repeat 8.6e-08 32.3 0.7 4.6 6.7 0.1 8.7 11 Sec1 Sec1 family 1.4e-07 31.8 43.3 19 5.4 0.0 17.0 20 RPN7 26S proteasome subunit RPN7 2.8e-07 31.3 19.4 9.8 7.1 0.1 12.0 14 TPR_19 Tetratricopeptide repeat 3.5e-06 27.8 11.4 55 4.7 0.0 12.3 14 Bleomycin_resist_prot_dom Bleomycin resistance protein domai 6.5e-06 26.6 0.1 3e+02 2.0 0.0 10.6 13 CODH_A_N Carbon monoxide dehydrogenase subu 1.5e-05 26.0 26.6 6.6 7.9 0.2 9.7 12 DUF4810 Domain of unknown function (DUF481 1.8e-05 24.6 12.6 75 3.4 0.0 13.4 17 SHNi-TPR SHNi-TPR 4.2e-05 24.4 3.0 38 5.1 0.0 7.6 10 DHR-2_Lobe_A DHR-2, Lobe A 5.2e-05 23.9 41.1 81 4.0 0.0 16.6 17 DUF7018 Domain of unknown function (DUF701 0.00034 21.0 4.4 2.1e+02 2.3 0.0 10.4 11 TPR_BSK1_C Serine/threonine-protein kinase BS ------ inclusion threshold ------ 0.027 14.1 2.2 35 3.9 0.0 4.7 5 TRAPPC9-Trs120 Trs120/TRAPPC9, N-terminal domain 0.031 15.0 0.0 63 4.3 0.0 5.4 5 NAD_binding_11 NAD-binding of NADP-dependent 3-hy 0.1 13.2 0.2 1.1e+03 0.2 0.0 6.5 6 DDT DDT domain 0.28 11.9 10.3 1.7e+02 2.9 0.1 7.0 10 FliJ Flagellar FliJ protein 0.47 10.8 31.2 26 5.1 0.1 9.9 12 ARM_TT21_C Tetratricopeptide repeat protein 2 5.5 7.7 19.1 47 4.7 0.1 7.9 10 PT26-6P_helical PT26-6P, helical domain 6.4 7.3 52.2 7 7.2 0.0 15.5 17 Mre11_C_bact Mre11 C-terminal domain, bacteria Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.1 1.3e-07 7.7e-05 4 75 .. 10 79 .. 7 81 .. 0.89 2 ! 51.7 0.4 1.7e-16 1e-13 4 75 .. 90 159 .. 87 161 .. 0.95 3 ! 57.1 0.2 3.6e-18 2.2e-15 5 76 .. 171 240 .. 167 241 .. 0.96 4 ! 61.6 0.2 1.4e-19 8.7e-17 5 77 .] 251 321 .. 247 321 .. 0.97 5 ! 56.5 0.1 5.5e-18 3.4e-15 4 76 .. 330 400 .. 327 401 .. 0.96 6 ! 61.7 0.1 1.3e-19 8.2e-17 5 77 .] 411 481 .. 407 481 .. 0.97 7 ! 55.1 0.4 1.5e-17 9.1e-15 4 77 .] 490 561 .. 487 561 .. 0.96 8 ! 54.4 0.3 2.5e-17 1.5e-14 4 77 .] 570 641 .. 567 641 .. 0.96 9 ! 69.5 0.5 4.7e-22 2.9e-19 4 77 .] 650 721 .. 647 721 .. 0.97 10 ! 59.2 0.5 7.9e-19 4.8e-16 4 77 .] 730 801 .. 728 801 .. 0.97 11 ! 41.7 0.0 2.2e-13 1.4e-10 4 75 .. 810 879 .. 808 881 .. 0.94 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 1.3e-07 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ + + + g + +A+e++ek l + +l +d ++ ++nL+ ++ lgd+++A++++e+ leia FUN_002341-T1 10 NAYGYISIAFHSKGYFRKAIEYHEKHLKVTMEL--GDCAGEEKGYQNLAYAFPSLGDFRKAIKYHEKHLEIA 79 67766666777788899**************99..99*********************************98 PP == domain 2 score: 51.7 bits; conditional E-value: 1.7e-16 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y+ l d+++A++++e+ leia FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEV--GHRVGEGNAYGSLGNAYQSLCDFRKAIKYHEKDLEIA 159 799******************************..99*****************************988886 PP == domain 3 score: 57.1 bits; conditional E-value: 3.6e-18 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 a+ l+++++ lg++ +A+e++ek +a+++ d+ ++ +a+ nLg +y+ l ++++A+e++e++lei + FUN_002341-T1 171 AYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEV--SDRVGEGRAYGNLGNAYQSLCNFRKAIEYYEKCLEIVK 240 7888****************************..9**********************************987 PP == domain 4 score: 61.6 bits; conditional E-value: 1.4e-19 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 a+ nl+ +++ lg++++A+e++ek lela+++ d+ ++ ++ Lg y+ lgd+++A+e++e+ leia++ FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV--SDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKE 321 799*****************************..9***********************************986 PP == domain 5 score: 56.5 bits; conditional E-value: 5.5e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiae 76 +a+ l++ ++ lg++ +A+e++ek le+a+++ d+ ++ a+ Lg +y+ l ++++A+e++e++lei + FUN_002341-T1 330 RAYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGSLGNAYQSLCNFRKAIEYYEKCLEIVK 400 68888****************************..9**********************************987 PP == domain 6 score: 61.7 bits; conditional E-value: 1.3e-19 TPR_12 5 alnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 ++ nl+ +++ lg++++A+e++ek lela+++ d+ ++ ++ Lg y+ lgd+++A+e++e+ leia++ FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV--SDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKE 481 799*****************************..9***********************************986 PP == domain 7 score: 55.1 bits; conditional E-value: 1.5e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l++ ++ lg++ +A+e++ek le+a+++ d ++ a+ Lg +y+ lgd+++A+e++e+ le+a++ FUN_002341-T1 490 RAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEV--RDGVGEGSAYGHLGNAYRSLGDFRKAIEYHEKHLELAKE 561 68888****************************..89999*******************************986 PP == domain 8 score: 54.4 bits; conditional E-value: 2.5e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+++++ lg++ +A+e++ek le+a+++ d+ ++ +a+ Lg +y+ lg++++A+e++e+ leia++ FUN_002341-T1 570 NAYGSLGNAYWSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGRAYGSLGNAYQSLGHFQKAIEYHEKDLEIAKE 641 78989****************************..9*******************************9999985 PP == domain 9 score: 69.5 bits; conditional E-value: 4.7e-22 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+++++ lg++++A+e++ek le+a+++ d+ ++ +a+ nLg++y+ lgd+++A+e++e+ le+a++ FUN_002341-T1 650 SAYGNLGNAYQSLGDFQKAIEYHEKHLEIAKEV--SDRVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKE 721 7999*****************************..9***********************************986 PP == domain 10 score: 59.2 bits; conditional E-value: 7.9e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ +l+++++ lg++ +A+e++ek le+a ++ +++ ++ +a+ nLg++y+ lgd+++A+e++e+ le+a++ FUN_002341-T1 730 SAYGCLGSAYQSLGDFRKAIEYHEKRLEIAIEV--GHRVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKE 801 68999****************************..99**********************************986 PP == domain 11 score: 41.7 bits; conditional E-value: 2.2e-13 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ +l+++++ lg++ +A+e++ek+l + ++ +++ ++ ++++n+g+ y+ lg++e Al+ + a++++ FUN_002341-T1 810 SAYGCLGNAYQSLGDFRKAIEYHEKCLKIDIEV--GNRAGEGISHHNIGQGYFSLGQFENALDKFISAVKVF 879 68999****************************..99*************************9998887765 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 0.00028 0.17 8 35 .. 18 45 .. 15 46 .. 0.91 2 ! 16.8 0.0 1.3e-05 0.0076 3 35 .. 53 85 .. 52 86 .. 0.91 3 ! 28.9 0.0 1.6e-09 9.7e-07 1 35 [. 91 125 .. 91 126 .. 0.94 4 ! 17.1 0.0 9.8e-06 0.006 1 35 [. 131 165 .. 131 166 .. 0.93 5 ! 21.4 0.0 4e-07 0.00024 1 35 [. 171 205 .. 171 206 .. 0.94 6 ! 23.1 0.0 1.2e-07 7e-05 1 35 [. 211 245 .. 211 246 .. 0.96 7 ! 31.6 0.1 2.1e-10 1.3e-07 1 35 [. 251 285 .. 251 286 .. 0.96 8 ! 22.8 0.0 1.4e-07 8.8e-05 2 35 .. 292 325 .. 291 326 .. 0.93 9 ! 20.8 0.1 6.1e-07 0.00037 1 35 [. 331 365 .. 331 366 .. 0.93 10 ! 21.4 0.0 4.1e-07 0.00025 1 35 [. 371 405 .. 371 406 .. 0.95 11 ! 31.0 0.0 3.4e-10 2.1e-07 1 35 [. 411 445 .. 411 446 .. 0.95 12 ! 22.8 0.0 1.4e-07 8.8e-05 2 35 .. 452 485 .. 451 486 .. 0.93 13 ! 26.1 0.0 1.3e-08 7.9e-06 1 34 [. 491 524 .. 491 525 .. 0.94 14 ! 31.7 0.1 1.9e-10 1.2e-07 1 35 [. 531 565 .. 531 566 .. 0.95 15 ! 29.9 0.0 7.8e-10 4.7e-07 1 35 [. 571 605 .. 571 606 .. 0.95 16 ! 26.3 0.0 1.1e-08 6.4e-06 1 35 [. 611 645 .. 611 646 .. 0.95 17 ! 33.2 0.0 6.7e-11 4.1e-08 1 35 [. 651 685 .. 651 686 .. 0.96 18 ! 30.7 0.0 4.3e-10 2.6e-07 1 35 [. 691 725 .. 691 726 .. 0.95 19 ! 21.2 0.0 4.8e-07 0.00029 5 35 .. 735 765 .. 731 766 .. 0.92 20 ! 31.6 0.1 2.1e-10 1.3e-07 1 35 [. 771 805 .. 771 806 .. 0.96 21 ! 20.7 0.0 6.6e-07 0.0004 5 35 .. 815 845 .. 811 846 .. 0.90 22 ? 3.1 0.0 0.31 1.9e+02 1 24 [. 851 874 .. 851 878 .. 0.89 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00028 TPR_7 8 iyrklGdydeAirlyerlLalakdpedr 35 +++++G +++Ai+++e++L ++++++d FUN_002341-T1 18 AFHSKGYFRKAIEYHEKHLKVTMELGDC 45 7999*****************9999986 PP == domain 2 score: 16.8 bits; conditional E-value: 1.3e-05 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La ++ +lGd+++Ai+++e++L++a + ++r FUN_002341-T1 53 QNLAYAFPSLGDFRKAIKYHEKHLEIAIEAGHR 85 6999**********************9887776 PP == domain 3 score: 28.9 bits; conditional E-value: 1.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++a + ++r FUN_002341-T1 91 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHR 125 789*************************9988876 PP == domain 4 score: 17.1 bits; conditional E-value: 9.8e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++l d+++Ai+++e+ L++a + ++r FUN_002341-T1 131 AYGSLGNAYQSLCDFRKAIKYHEKDLEIAIEVGHR 165 7899************************9888876 PP == domain 5 score: 21.4 bits; conditional E-value: 4e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y+ lGd+++Ai+++e++ +ak+ +dr FUN_002341-T1 171 AYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEVSDR 205 7899*********************9999999987 PP == domain 6 score: 23.1 bits; conditional E-value: 1.2e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++l ++++Ai++ye++L+++k+ +dr FUN_002341-T1 211 AYGNLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDR 245 789****************************9998 PP == domain 7 score: 31.6 bits; conditional E-value: 2.1e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L+lak+ +dr FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDR 285 789****************************9998 PP == domain 8 score: 22.8 bits; conditional E-value: 1.4e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L++ y++lGd+++Ai+++e++L++ak+ +dr FUN_002341-T1 292 YGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSDR 325 6789999***********************9998 PP == domain 9 score: 20.8 bits; conditional E-value: 6.1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L++ y+ lGd+++Ai+++e++L++ak+ +dr FUN_002341-T1 331 AYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEVSDR 365 67789999***********************9998 PP == domain 10 score: 21.4 bits; conditional E-value: 4.1e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++l ++++Ai++ye++L+++k+ +dr FUN_002341-T1 371 AYGSLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDR 405 7899***************************9998 PP == domain 11 score: 31.0 bits; conditional E-value: 3.4e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 ++++L+ +y++lGd+++Ai+++e++L+lak+ +dr FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDR 445 578****************************9998 PP == domain 12 score: 22.8 bits; conditional E-value: 1.4e-07 TPR_7 2 LsaLariyrklGdydeAirlyerlLalakdpedr 35 +++L++ y++lGd+++Ai+++e++L++ak+ +dr FUN_002341-T1 452 YGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSDR 485 6789999***********************9998 PP == domain 13 score: 26.1 bits; conditional E-value: 1.3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L++ y++lGd+++Ai+++e++L++ak+ +d FUN_002341-T1 491 AYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEVRD 524 7899**************************9876 PP == domain 14 score: 31.7 bits; conditional E-value: 1.9e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a++ L+++yr+lGd+++Ai+++e++L+lak+ ++r FUN_002341-T1 531 AYGHLGNAYRSLGDFRKAIEYHEKHLELAKEVGHR 565 6789***************************9987 PP == domain 15 score: 29.9 bits; conditional E-value: 7.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lGd+++Ai+++e++L++ak+ +dr FUN_002341-T1 571 AYGSLGNAYWSLGDFRKAIEYHEKHLEIAKEVSDR 605 7899***************************9998 PP == domain 16 score: 26.3 bits; conditional E-value: 1.1e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lG +++Ai+++e+ L++ak+ +dr FUN_002341-T1 611 AYGSLGNAYQSLGHFQKAIEYHEKDLEIAKEVSDR 645 7899***************************9998 PP == domain 17 score: 33.2 bits; conditional E-value: 6.7e-11 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002341-T1 651 AYGNLGNAYQSLGDFQKAIEYHEKHLEIAKEVSDR 685 789****************************9998 PP == domain 18 score: 30.7 bits; conditional E-value: 4.3e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L+lak+ ++r FUN_002341-T1 691 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSHR 725 789***************************99887 PP == domain 19 score: 21.2 bits; conditional E-value: 4.8e-07 TPR_7 5 LariyrklGdydeAirlyerlLalakdpedr 35 L+++y++lGd+++Ai+++e+ L++a + ++r FUN_002341-T1 735 LGSAYQSLGDFRKAIEYHEKRLEIAIEVGHR 765 9***********************9888876 PP == domain 20 score: 31.6 bits; conditional E-value: 2.1e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L+lak+ +dr FUN_002341-T1 771 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDR 805 789****************************9998 PP == domain 21 score: 20.7 bits; conditional E-value: 6.6e-07 TPR_7 5 LariyrklGdydeAirlyerlLalakdpedr 35 L+++y++lGd+++Ai+++e++L ++ + ++r FUN_002341-T1 815 LGNAYQSLGDFRKAIEYHEKCLKIDIEVGNR 845 9********************9998887776 PP == domain 22 score: 3.1 bits; conditional E-value: 0.31 TPR_7 1 aLsaLariyrklGdydeAirlyer 24 +++++++ y +lG++++A++ + FUN_002341-T1 851 SHHNIGQGYFSLGQFENALDKFIS 874 5899***************99987 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.1 0.7 4.3e+02 17 29 .. 25 37 .. 17 38 .. 0.72 2 ! 13.8 0.2 9.3e-05 0.057 2 30 .. 50 78 .. 49 79 .. 0.93 3 ! 30.5 0.6 4.7e-10 2.8e-07 2 30 .. 90 118 .. 89 119 .. 0.95 4 ! 17.6 0.5 5.9e-06 0.0036 2 26 .. 130 154 .. 129 159 .. 0.93 5 ! 23.4 0.4 8.2e-08 5e-05 2 30 .. 170 198 .. 169 201 .. 0.90 6 ! 33.9 1.4 4e-11 2.4e-08 2 30 .. 210 238 .. 209 240 .. 0.97 7 ! 29.7 0.8 8.6e-10 5.2e-07 3 31 .. 251 279 .. 250 281 .. 0.95 8 ! 22.2 0.0 2e-07 0.00012 3 31 .. 291 319 .. 290 321 .. 0.93 9 ! 20.4 0.2 7.6e-07 0.00046 2 31 .. 330 359 .. 329 361 .. 0.94 10 ! 30.4 0.6 5.2e-10 3.1e-07 3 30 .. 371 398 .. 369 400 .. 0.96 11 ! 28.7 0.4 1.7e-09 1e-06 3 31 .. 411 439 .. 411 441 .. 0.94 12 ! 22.2 0.0 2e-07 0.00012 3 31 .. 451 479 .. 450 481 .. 0.93 13 ! 23.2 0.1 9.8e-08 6e-05 2 31 .. 490 519 .. 489 521 .. 0.94 14 ! 28.1 0.3 2.7e-09 1.7e-06 3 31 .. 531 559 .. 529 561 .. 0.94 15 ! 26.8 0.3 7.2e-09 4.4e-06 2 31 .. 570 599 .. 569 601 .. 0.94 16 ! 21.3 0.3 3.8e-07 0.00023 2 26 .. 610 634 .. 609 640 .. 0.92 17 ! 32.5 0.5 1.1e-10 6.7e-08 3 31 .. 651 679 .. 649 681 .. 0.94 18 ! 30.6 0.8 4.3e-10 2.6e-07 2 31 .. 690 719 .. 689 721 .. 0.94 19 ! 19.0 0.2 2.1e-06 0.0013 3 26 .. 731 754 .. 729 759 .. 0.91 20 ! 30.6 0.8 4.3e-10 2.6e-07 2 31 .. 770 799 .. 769 801 .. 0.94 21 ! 30.2 0.3 5.8e-10 3.5e-07 3 31 .. 811 839 .. 809 840 .. 0.96 22 ! 11.3 0.0 0.00055 0.34 4 27 .. 852 875 .. 850 879 .. 0.84 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.7 TPR_1 17 ydeAleyyekALe 29 + +A+ey ek L+ FUN_002341-T1 25 FRKAIEYHEKHLK 37 7789999988887 PP == domain 2 score: 13.8 bits; conditional E-value: 9.3e-05 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k + nl++a+ +lg++ +A++y ek Le+ FUN_002341-T1 50 KGYQNLAYAFPSLGDFRKAIKYHEKHLEI 78 5799***********************98 PP == domain 3 score: 30.5 bits; conditional E-value: 4.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey ek Le+ FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKAIEYHEKHLEI 118 69*************************98 PP == domain 4 score: 17.6 bits; conditional E-value: 5.9e-06 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ lGnay++l ++ +A++y ek FUN_002341-T1 130 NAYGSLGNAYQSLCDFRKAIKYHEK 154 59********************998 PP == domain 5 score: 23.4 bits; conditional E-value: 8.2e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay+ lg++ +A+ey ek ++ FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEYHEKHFKI 198 79*********************996665 PP == domain 6 score: 33.9 bits; conditional E-value: 4e-11 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++l ++ +A+eyyek+Le+ FUN_002341-T1 210 RAYGNLGNAYQSLCNFRKAIEYYEKCLEI 238 79*************************98 PP == domain 7 score: 29.7 bits; conditional E-value: 8.6e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlG ay++lg++++A+ey ek Lel FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEYHEKHLELA 279 8**************************96 PP == domain 8 score: 22.2 bits; conditional E-value: 2e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++ lGn y++lg++ +A+ey ek Le+ FUN_002341-T1 291 TYGSLGNDYQSLGDFRKAIEYHEKHLEIA 319 6899***********************96 PP == domain 9 score: 20.4 bits; conditional E-value: 7.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lG y+ lg++ +A+ey ek Le+ FUN_002341-T1 330 RAYGSLGDDYQLLGDFRKAIEYHEKHLEIA 359 69**************************96 PP == domain 10 score: 30.4 bits; conditional E-value: 5.2e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ lGnay++l ++ +A+eyyek+Le+ FUN_002341-T1 371 AYGSLGNAYQSLCNFRKAIEYYEKCLEI 398 89************************98 PP == domain 11 score: 28.7 bits; conditional E-value: 1.7e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++ nlG ay++lg++++A+ey ek Lel FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHEKHLELA 439 599************************96 PP == domain 12 score: 22.2 bits; conditional E-value: 2e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++ lGn y++lg++ +A+ey ek Le+ FUN_002341-T1 451 TYGSLGNDYQSLGDFRKAIEYHEKHLEIA 479 6899***********************96 PP == domain 13 score: 23.2 bits; conditional E-value: 9.8e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGn y++lg++ +A+ey ek Le+ FUN_002341-T1 490 RAYGSLGNGYQSLGDFRKAIEYHEKHLEIA 519 69**************************96 PP == domain 14 score: 28.1 bits; conditional E-value: 2.7e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek Lel FUN_002341-T1 531 AYGHLGNAYRSLGDFRKAIEYHEKHLELA 559 99*************************96 PP == domain 15 score: 26.8 bits; conditional E-value: 7.2e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay +lg++ +A+ey ek Le+ FUN_002341-T1 570 NAYGSLGNAYWSLGDFRKAIEYHEKHLEIA 599 59**************************96 PP == domain 16 score: 21.3 bits; conditional E-value: 3.8e-07 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ lGnay++lg +++A+ey ek FUN_002341-T1 610 RAYGSLGNAYQSLGHFQKAIEYHEK 634 69********************998 PP == domain 17 score: 32.5 bits; conditional E-value: 1.1e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGnay++lg++++A+ey ek Le+ FUN_002341-T1 651 AYGNLGNAYQSLGDFQKAIEYHEKHLEIA 679 9**************************96 PP == domain 18 score: 30.6 bits; conditional E-value: 4.3e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay++lg++++A+ey ek Lel FUN_002341-T1 690 NAYGNLGIAYQSLGDFQKAIEYHEKHLELA 719 69**************************96 PP == domain 19 score: 19.0 bits; conditional E-value: 2.1e-06 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ lG ay++lg++ +A+ey ek FUN_002341-T1 731 AYGCLGSAYQSLGDFRKAIEYHEK 754 899******************998 PP == domain 20 score: 30.6 bits; conditional E-value: 4.3e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlG ay++lg++++A+ey ek Lel FUN_002341-T1 770 NAYGNLGIAYQSLGDFQKAIEYHEKHLELA 799 69**************************96 PP == domain 21 score: 30.2 bits; conditional E-value: 5.8e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek+L+++ FUN_002341-T1 811 AYGCLGNAYQSLGDFRKAIEYHEKCLKID 839 899************************98 PP == domain 22 score: 11.3 bits; conditional E-value: 0.00055 TPR_1 4 lynlGnayfklgkydeAleyyekA 27 + n+G+ yf+lg+++ Al+ + A FUN_002341-T1 852 HHNIGQGYFSLGQFENALDKFISA 875 88****************966555 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 4.5 2.7e+03 23 36 .. 23 36 .. 15 38 .. 0.87 2 ? 2.3 0.0 0.43 2.6e+02 5 33 .. 52 80 .. 52 82 .. 0.85 3 ! 18.1 0.0 4.4e-06 0.0027 4 35 .. 91 122 .. 89 122 .. 0.91 4 ! 8.8 0.0 0.0038 2.3 4 35 .. 131 162 .. 129 162 .. 0.93 5 ! 12.7 0.0 0.00023 0.14 3 35 .. 170 202 .. 169 205 .. 0.91 6 ! 18.7 0.1 2.9e-06 0.0018 4 35 .. 211 242 .. 209 245 .. 0.94 7 ! 18.8 0.0 2.7e-06 0.0016 4 35 .. 251 282 .. 250 285 .. 0.94 8 ! 16.6 0.0 1.4e-05 0.0084 3 35 .. 290 322 .. 289 325 .. 0.95 9 ! 11.0 0.0 0.00079 0.48 4 35 .. 331 362 .. 329 365 .. 0.94 10 ! 15.9 0.0 2.2e-05 0.013 3 35 .. 370 402 .. 369 405 .. 0.94 11 ! 19.1 0.0 2.2e-06 0.0013 4 35 .. 411 442 .. 410 445 .. 0.94 12 ! 16.6 0.0 1.4e-05 0.0084 3 35 .. 450 482 .. 449 485 .. 0.95 13 ! 12.3 0.0 0.0003 0.18 4 35 .. 491 522 .. 489 523 .. 0.93 14 ! 16.9 0.0 1.1e-05 0.0067 3 35 .. 530 562 .. 529 562 .. 0.94 15 ! 16.8 0.0 1.2e-05 0.007 4 35 .. 571 602 .. 569 605 .. 0.94 16 ! 20.1 0.0 1.1e-06 0.00065 4 35 .. 611 642 .. 609 645 .. 0.94 17 ! 22.7 0.0 1.6e-07 9.6e-05 3 35 .. 650 682 .. 649 685 .. 0.95 18 ! 19.0 0.0 2.4e-06 0.0015 4 35 .. 691 722 .. 689 723 .. 0.94 19 ! 12.4 0.0 0.00029 0.17 3 34 .. 730 761 .. 729 762 .. 0.90 20 ! 19.2 0.0 2e-06 0.0012 4 35 .. 771 802 .. 769 805 .. 0.94 21 ! 18.0 0.0 5e-06 0.003 3 31 .. 810 838 .. 809 838 .. 0.95 22 ? 1.9 0.0 0.58 3.5e+02 6 23 .. 853 870 .. 852 878 .. 0.90 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 4.5 TPR_10 23 elleealairervl 36 ++++a++ +e++l FUN_002341-T1 23 GYFRKAIEYHEKHL 36 5899***9999988 PP == domain 2 score: 2.3 bits; conditional E-value: 0.43 TPR_10 5 lnnLanalraqgryeeAeelleealaire 33 + nLa a ++g++ A +++e+ l+i+ FUN_002341-T1 52 YQNLAYAFPSLGDFRKAIKYHEKHLEIAI 80 56999999999*********999888865 PP == domain 3 score: 18.1 bits; conditional E-value: 4.4e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++g++ A e++e+ l+i+ +v FUN_002341-T1 91 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEV 122 899*********************99998765 PP == domain 4 score: 8.8 bits; conditional E-value: 0.0038 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++ ++ A +++e+ l+i+ +v FUN_002341-T1 131 AYGSLGNAYQSLCDFRKAIKYHEKDLEIAIEV 162 7999***********************98776 PP == domain 5 score: 12.7 bits; conditional E-value: 0.00023 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 +++ L+na++ +g++ A e++e+ ++i+++v FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEV 202 5899*********************99998887 PP == domain 6 score: 18.7 bits; conditional E-value: 2.9e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na++++ ++ A e++e++l+i ++v FUN_002341-T1 211 AYGNLGNAYQSLCNFRKAIEYYEKCLEIVKEV 242 89**************************9987 PP == domain 7 score: 18.8 bits; conditional E-value: 2.7e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a++++g+++ A e++e+ l+++++v FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 282 799************************99998 PP == domain 8 score: 16.6 bits; conditional E-value: 1.4e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+n ++++g++ A e++e+ l+i+++v FUN_002341-T1 290 STYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEV 322 799***************************998 PP == domain 9 score: 11.0 bits; conditional E-value: 0.00079 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+ ++ +g++ A e++e+ l+i+++v FUN_002341-T1 331 AYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEV 362 7999*************************998 PP == domain 10 score: 15.9 bits; conditional E-value: 2.2e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+na++++ ++ A e++e++l+i ++v FUN_002341-T1 370 SAYGSLGNAYQSLCNFRKAIEYYEKCLEIVKEV 402 6899*************************9987 PP == domain 11 score: 19.1 bits; conditional E-value: 2.2e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a++++g+++ A e++e+ l+++++v FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 442 899************************99998 PP == domain 12 score: 16.6 bits; conditional E-value: 1.4e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+n ++++g++ A e++e+ l+i+++v FUN_002341-T1 450 STYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEV 482 799***************************998 PP == domain 13 score: 12.3 bits; conditional E-value: 0.0003 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+n ++++g++ A e++e+ l+i+++v FUN_002341-T1 491 AYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEV 522 7999***********************99987 PP == domain 14 score: 16.9 bits; conditional E-value: 1.1e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ +L+na+r++g++ A e++e+ l+++++v FUN_002341-T1 530 SAYGHLGNAYRSLGDFRKAIEYHEKHLELAKEV 562 799**********************99999986 PP == domain 15 score: 16.8 bits; conditional E-value: 1.2e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+++v FUN_002341-T1 571 AYGSLGNAYWSLGDFRKAIEYHEKHLEIAKEV 602 7999*************************998 PP == domain 16 score: 20.1 bits; conditional E-value: 1.1e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g ++ A e++e+ l+i+++v FUN_002341-T1 611 AYGSLGNAYQSLGHFQKAIEYHEKDLEIAKEV 642 8999**************************98 PP == domain 17 score: 22.7 bits; conditional E-value: 1.6e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g+++ A e++e+ l+i+++v FUN_002341-T1 650 SAYGNLGNAYQSLGDFQKAIEYHEKHLEIAKEV 682 79****************************998 PP == domain 18 score: 19.0 bits; conditional E-value: 2.4e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a++++g+++ A e++e+ l+++++v FUN_002341-T1 691 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 722 89**********************99999987 PP == domain 19 score: 12.4 bits; conditional E-value: 0.00029 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ L+ a++++g++ A e++e+ l+i+ + FUN_002341-T1 730 SAYGCLGSAYQSLGDFRKAIEYHEKRLEIAIE 761 68999*******************98888766 PP == domain 20 score: 19.2 bits; conditional E-value: 2e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a++++g+++ A e++e+ l+++++v FUN_002341-T1 771 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 802 89*************************99998 PP == domain 21 score: 18.0 bits; conditional E-value: 5e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealai 31 s++ L+na++++g++ A e++e++l+i FUN_002341-T1 810 SAYGCLGNAYQSLGDFRKAIEYHEKCLKI 838 68999**********************86 PP == domain 22 score: 1.9 bits; conditional E-value: 0.58 TPR_10 6 nnLanalraqgryeeAee 23 +n+++ ++++g++e A++ FUN_002341-T1 853 HNIGQGYFSLGQFENALD 870 89************9986 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 1.9 1.1e+03 10 26 .. 18 34 .. 10 38 .. 0.74 2 ! 8.8 0.1 0.0048 2.9 3 30 .. 51 78 .. 49 79 .. 0.89 3 ! 19.5 0.2 1.7e-06 0.001 3 30 .. 91 118 .. 89 119 .. 0.90 4 ? 7.4 0.2 0.013 7.8 3 26 .. 131 154 .. 129 159 .. 0.87 5 ! 14.4 0.2 7.3e-05 0.044 2 26 .. 170 194 .. 169 201 .. 0.87 6 ! 25.4 0.8 2.2e-08 1.4e-05 2 30 .. 210 238 .. 209 238 .. 0.97 7 ! 18.5 0.3 3.6e-06 0.0022 3 32 .. 251 280 .. 249 281 .. 0.92 8 ! 9.7 0.1 0.0024 1.4 3 32 .. 291 320 .. 289 321 .. 0.88 9 ! 9.8 0.1 0.0022 1.3 2 32 .. 330 360 .. 329 361 .. 0.91 10 ! 21.9 0.7 2.9e-07 0.00018 2 30 .. 370 398 .. 369 398 .. 0.96 11 ! 17.4 0.2 8.4e-06 0.0051 3 32 .. 411 440 .. 410 441 .. 0.91 12 ! 9.7 0.1 0.0024 1.4 3 32 .. 451 480 .. 449 481 .. 0.88 13 ! 12.5 0.1 0.00032 0.19 2 32 .. 490 520 .. 489 521 .. 0.92 14 ! 19.2 0.1 2.1e-06 0.0013 2 32 .. 530 560 .. 529 561 .. 0.92 15 ! 19.4 0.1 1.9e-06 0.0012 3 32 .. 571 600 .. 569 601 .. 0.91 16 ! 16.6 0.2 1.4e-05 0.0088 2 30 .. 610 638 .. 609 641 .. 0.88 17 ! 21.9 0.3 2.9e-07 0.00018 2 32 .. 650 680 .. 649 681 .. 0.92 18 ! 18.7 0.4 3.1e-06 0.0019 3 32 .. 691 720 .. 689 721 .. 0.92 19 ! 13.1 0.1 0.00019 0.12 3 30 .. 731 758 .. 729 759 .. 0.84 20 ! 18.7 0.4 3.1e-06 0.0019 3 32 .. 771 800 .. 769 801 .. 0.92 21 ! 21.0 0.1 5.5e-07 0.00034 3 31 .. 811 839 .. 809 839 .. 0.92 22 ? 4.8 0.0 0.088 54 4 21 .. 852 869 .. 851 878 .. 0.87 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.9 TPR_8 10 iylklgdyeeAkeyyek 26 + +++g++ +A+ey ek FUN_002341-T1 18 AFHSKGYFRKAIEYHEK 34 66788888888888655 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0048 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 y+nl+++ +lgd+ +A++y ek le+ FUN_002341-T1 51 GYQNLAYAFPSLGDFRKAIKYHEKHLEI 78 69*******************9987776 PP == domain 3 score: 19.5 bits; conditional E-value: 1.7e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay nlG++y++lgd+ +A+ey ek le+ FUN_002341-T1 91 AYGNLGNAYQSLGDFRKAIEYHEKHLEI 118 9********************9987776 PP == domain 4 score: 7.4 bits; conditional E-value: 0.013 TPR_8 3 ayynlGliylklgdyeeAkeyyek 26 ay lG++y++l d+ +A++y ek FUN_002341-T1 131 AYGSLGNAYQSLCDFRKAIKYHEK 154 899*****************9776 PP == domain 5 score: 14.4 bits; conditional E-value: 7.3e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay lG++y+ lgd+ +A+ey ek FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEYHEK 194 69********************877 PP == domain 6 score: 25.4 bits; conditional E-value: 2.2e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay nlG++y++l ++ +A+eyyek+le+ FUN_002341-T1 210 RAYGNLGNAYQSLCNFRKAIEYYEKCLEI 238 89*************************97 PP == domain 7 score: 18.5 bits; conditional E-value: 3.6e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG +y++lgd+++A+ey ek lel++ FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEYHEKHLELAK 280 8********************999998875 PP == domain 8 score: 9.7 bits; conditional E-value: 0.0024 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y lG+ y++lgd+ +A+ey ek le+++ FUN_002341-T1 291 TYGSLGNDYQSLGDFRKAIEYHEKHLEIAK 320 68889999*************999988875 PP == domain 9 score: 9.8 bits; conditional E-value: 0.0022 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay lG+ y+ lgd+ +A+ey ek le+++ FUN_002341-T1 330 RAYGSLGDDYQLLGDFRKAIEYHEKHLEIAK 360 79********************999998875 PP == domain 10 score: 21.9 bits; conditional E-value: 2.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++l ++ +A+eyyek+le+ FUN_002341-T1 370 SAYGSLGNAYQSLCNFRKAIEYYEKCLEI 398 589************************97 PP == domain 11 score: 17.4 bits; conditional E-value: 8.4e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y nlG +y++lgd+++A+ey ek lel++ FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHEKHLELAK 440 699******************999998875 PP == domain 12 score: 9.7 bits; conditional E-value: 0.0024 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y lG+ y++lgd+ +A+ey ek le+++ FUN_002341-T1 451 TYGSLGNDYQSLGDFRKAIEYHEKHLEIAK 480 68889999*************999988875 PP == domain 13 score: 12.5 bits; conditional E-value: 0.00032 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay lG+ y++lgd+ +A+ey ek le+++ FUN_002341-T1 490 RAYGSLGNGYQSLGDFRKAIEYHEKHLEIAK 520 79********************999998875 PP == domain 14 score: 19.2 bits; conditional E-value: 2.1e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay +lG++y++lgd+ +A+ey ek lel++ FUN_002341-T1 530 SAYGHLGNAYRSLGDFRKAIEYHEKHLELAK 560 59********************999998875 PP == domain 15 score: 19.4 bits; conditional E-value: 1.9e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002341-T1 571 AYGSLGNAYWSLGDFRKAIEYHEKHLEIAK 600 89*******************999998875 PP == domain 16 score: 16.6 bits; conditional E-value: 1.4e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lg +++A+ey ek le+ FUN_002341-T1 610 RAYGSLGNAYQSLGHFQKAIEYHEKDLEI 638 89********************8886666 PP == domain 17 score: 21.9 bits; conditional E-value: 2.9e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+++A+ey ek le+++ FUN_002341-T1 650 SAYGNLGNAYQSLGDFQKAIEYHEKHLEIAK 680 59********************999998875 PP == domain 18 score: 18.7 bits; conditional E-value: 3.1e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG +y++lgd+++A+ey ek lel++ FUN_002341-T1 691 AYGNLGIAYQSLGDFQKAIEYHEKHLELAK 720 8********************999998875 PP == domain 19 score: 13.1 bits; conditional E-value: 0.00019 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG++y++lgd+ +A+ey ek le+ FUN_002341-T1 731 AYGCLGSAYQSLGDFRKAIEYHEKRLEI 758 56669****************8886665 PP == domain 20 score: 18.7 bits; conditional E-value: 3.1e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG +y++lgd+++A+ey ek lel++ FUN_002341-T1 771 AYGNLGIAYQSLGDFQKAIEYHEKHLELAK 800 8********************999998875 PP == domain 21 score: 21.0 bits; conditional E-value: 5.5e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay lG++y++lgd+ +A+ey ek+l++d FUN_002341-T1 811 AYGCLGNAYQSLGDFRKAIEYHEKCLKID 839 56669**********************98 PP == domain 22 score: 4.8 bits; conditional E-value: 0.088 TPR_8 4 yynlGliylklgdyeeAk 21 ++n+G+ y +lg++e+A FUN_002341-T1 852 HHNIGQGYFSLGQFENAL 869 799*************96 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.1 2.5 1.5e+03 3 23 .. 11 31 .. 9 35 .. 0.72 2 ? 2.0 0.1 0.71 4.3e+02 3 23 .. 51 71 .. 49 79 .. 0.85 3 ! 14.5 0.2 6.8e-05 0.041 3 23 .. 91 111 .. 89 118 .. 0.93 4 ! 9.3 0.2 0.0031 1.9 3 28 .. 131 156 .. 129 160 .. 0.84 5 ! 11.9 0.3 0.00047 0.28 2 23 .. 170 191 .. 169 194 .. 0.92 6 ! 25.3 0.5 2.3e-08 1.4e-05 2 30 .. 210 238 .. 209 241 .. 0.93 7 ! 14.8 0.4 5.5e-05 0.033 3 23 .. 251 271 .. 249 281 .. 0.86 8 ! 8.4 0.0 0.0063 3.8 6 23 .. 294 311 .. 290 321 .. 0.86 9 ! 8.7 0.2 0.0048 2.9 2 23 .. 330 351 .. 329 361 .. 0.87 10 ! 22.3 0.2 2.2e-07 0.00013 3 30 .. 371 398 .. 369 401 .. 0.91 11 ! 13.7 0.2 0.00012 0.072 4 23 .. 412 431 .. 410 441 .. 0.85 12 ! 8.4 0.0 0.0063 3.8 6 23 .. 454 471 .. 450 481 .. 0.86 13 ! 9.4 0.2 0.0029 1.8 2 23 .. 490 511 .. 489 521 .. 0.87 14 ! 13.4 0.4 0.00016 0.095 3 23 .. 531 551 .. 529 561 .. 0.85 15 ! 12.3 0.2 0.00035 0.21 3 23 .. 571 591 .. 569 601 .. 0.87 16 ! 14.3 0.3 8e-05 0.049 2 31 .. 610 639 .. 609 641 .. 0.85 17 ! 16.3 0.3 1.7e-05 0.011 3 23 .. 651 671 .. 649 681 .. 0.89 18 ! 15.2 0.5 4.1e-05 0.025 3 23 .. 691 711 .. 689 721 .. 0.86 19 ! 10.6 0.2 0.0012 0.74 3 23 .. 731 751 .. 729 757 .. 0.93 20 ! 15.2 0.5 4.1e-05 0.025 3 23 .. 771 791 .. 769 801 .. 0.86 21 ! 18.8 0.1 2.9e-06 0.0017 3 31 .. 811 839 .. 809 841 .. 0.94 22 ! 10.7 0.0 0.0011 0.69 4 29 .. 852 877 .. 850 881 .. 0.87 23 ? -0.7 0.0 5.1 3.1e+03 10 26 .. 910 926 .. 909 929 .. 0.84 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 2.5 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ + + a +g + +A+e+ FUN_002341-T1 11 AYGYISIAFHSKGYFRKAIEY 31 566677777777888888876 PP == domain 2 score: 2.0 bits; conditional E-value: 0.71 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nl++a lgd+ +A+++ FUN_002341-T1 51 GYQNLAYAFPSLGDFRKAIKY 71 678888888899*******98 PP == domain 3 score: 14.5 bits; conditional E-value: 6.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002341-T1 91 AYGNLGNAYQSLGDFRKAIEY 111 899****************98 PP == domain 4 score: 9.3 bits; conditional E-value: 0.0031 TPR_2 3 alynlGlayyklgdyeeAleayekAl 28 a+ lG+ay l d+ +A+++ ek l FUN_002341-T1 131 AYGSLGNAYQSLCDFRKAIKYHEKDL 156 7888****************966655 PP == domain 5 score: 11.9 bits; conditional E-value: 0.00047 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ay lgd+ +A+e+ FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEY 191 58889***************98 PP == domain 6 score: 25.3 bits; conditional E-value: 2.3e-08 TPR_2 2 ealynlGlayyklgdyeeAleayekAlel 30 +a+ nlG+ay l ++ +A+e+yek+le+ FUN_002341-T1 210 RAYGNLGNAYQSLCNFRKAIEYYEKCLEI 238 6899***********************98 PP == domain 7 score: 14.8 bits; conditional E-value: 5.5e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+++A+e+ FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEY 271 799*****************9 PP == domain 8 score: 8.4 bits; conditional E-value: 0.0063 TPR_2 6 nlGlayyklgdyeeAlea 23 lG+ y lgd+ +A+e+ FUN_002341-T1 294 SLGNDYQSLGDFRKAIEY 311 69***************8 PP == domain 9 score: 8.7 bits; conditional E-value: 0.0048 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ y lgd+ +A+e+ FUN_002341-T1 330 RAYGSLGDDYQLLGDFRKAIEY 351 57889****************9 PP == domain 10 score: 22.3 bits; conditional E-value: 2.2e-07 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a+ lG+ay l ++ +A+e+yek+le+ FUN_002341-T1 371 AYGSLGNAYQSLCNFRKAIEYYEKCLEI 398 6778**********************98 PP == domain 11 score: 13.7 bits; conditional E-value: 0.00012 TPR_2 4 lynlGlayyklgdyeeAlea 23 + nlG ay lgd+++A+e+ FUN_002341-T1 412 YGNLGIAYQSLGDFQKAIEY 431 779****************9 PP == domain 12 score: 8.4 bits; conditional E-value: 0.0063 TPR_2 6 nlGlayyklgdyeeAlea 23 lG+ y lgd+ +A+e+ FUN_002341-T1 454 SLGNDYQSLGDFRKAIEY 471 69***************8 PP == domain 13 score: 9.4 bits; conditional E-value: 0.0029 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ y lgd+ +A+e+ FUN_002341-T1 490 RAYGSLGNGYQSLGDFRKAIEY 511 57889****************8 PP == domain 14 score: 13.4 bits; conditional E-value: 0.00016 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002341-T1 531 AYGHLGNAYRSLGDFRKAIEY 551 7889****************9 PP == domain 15 score: 12.3 bits; conditional E-value: 0.00035 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay+ lgd+ +A+e+ FUN_002341-T1 571 AYGSLGNAYWSLGDFRKAIEY 591 7888****************9 PP == domain 16 score: 14.3 bits; conditional E-value: 8e-05 TPR_2 2 ealynlGlayyklgdyeeAleayekAleld 31 +a+ lG+ay lg++++A+e+ ek le++ FUN_002341-T1 610 RAYGSLGNAYQSLGHFQKAIEYHEKDLEIA 639 57889****************977777765 PP == domain 17 score: 16.3 bits; conditional E-value: 1.7e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+++A+e+ FUN_002341-T1 651 AYGNLGNAYQSLGDFQKAIEY 671 899*****************9 PP == domain 18 score: 15.2 bits; conditional E-value: 4.1e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+++A+e+ FUN_002341-T1 691 AYGNLGIAYQSLGDFQKAIEY 711 899*****************9 PP == domain 19 score: 10.6 bits; conditional E-value: 0.0012 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ +lG ay lgd+ +A+e+ FUN_002341-T1 731 AYGCLGSAYQSLGDFRKAIEY 751 7899***************98 PP == domain 20 score: 15.2 bits; conditional E-value: 4.1e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+++A+e+ FUN_002341-T1 771 AYGNLGIAYQSLGDFQKAIEY 791 899*****************9 PP == domain 21 score: 18.8 bits; conditional E-value: 2.9e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ +lG+ay lgd+ +A+e+ ek+l++d FUN_002341-T1 811 AYGCLGNAYQSLGDFRKAIEYHEKCLKID 839 7899***********************98 PP == domain 22 score: 10.7 bits; conditional E-value: 0.0011 TPR_2 4 lynlGlayyklgdyeeAleayekAle 29 ++n G+ y+ lg++e Al+ + A++ FUN_002341-T1 852 HHNIGQGYFSLGQFENALDKFISAVK 877 89*****************9966665 PP == domain 23 score: -0.7 bits; conditional E-value: 5.1 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002341-T1 910 SLLRIGKIDEALFAADE 926 67899*******98776 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 176.2 0.0 2.1e-54 1.3e-51 8 291 .] 1066 1328 .. 1061 1328 .. 0.89 Alignments for each domain: == domain 1 score: 176.2 bits; conditional E-value: 2.1e-54 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ ++Lviv dgaL +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ ++ k FUN_002341-T1 1066 YDAVIGPIEDLL-GPEDEELVIVSDGALCFIPWAAVIESIR---------IRIVPSLKSyqlISSVPEGYHKKTGA--LLVGNPCTKQ----LK 1143 899****99997.78888*****************988863.........55556654422266666666666666..*******885....47 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 +++lp +++E++++a++l++ ++l+g++at+ ++++ + ++++++H+a+Hg + ++L++ n + ed +L++++++ FUN_002341-T1 1144 KPLEPLPCAQKEVEMIAAILNT---RPLIGKEATKAEVMKRM-SSVGLIHIAAHGDEV-----TGQIALSP-NPGwtqfpkeEDYVLKMSDVQA 1227 777*****************88...8***************9.************999.....88899974.4445889999************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002341-T1 1228 ANLR-ARLVVLSCCHSGRGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATMEFMKRFYQHLKDGKTASAAVHQSMKSLRESEE----FSE 1316 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002341-T1 1317 MWYWAPFQLIGD 1328 ***********7 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 3.7 2.2e+03 5 29 .. 53 77 .. 50 80 .. 0.81 2 ? 5.6 0.0 0.076 46 6 29 .. 94 117 .. 90 119 .. 0.86 3 ? 4.6 0.0 0.16 98 5 29 .. 173 197 .. 170 204 .. 0.83 4 ? 6.7 0.0 0.035 21 6 30 .. 214 238 .. 210 244 .. 0.87 5 ? 5.7 0.0 0.075 46 7 31 .. 255 279 .. 250 284 .. 0.86 6 ? 2.7 0.0 0.68 4.1e+02 7 31 .. 295 319 .. 291 324 .. 0.85 7 ? 2.4 0.0 0.83 5e+02 6 31 .. 334 359 .. 330 364 .. 0.83 8 ? 6.8 0.0 0.033 20 6 30 .. 374 398 .. 370 404 .. 0.88 9 ? 5.3 0.0 0.095 58 7 31 .. 415 439 .. 411 444 .. 0.88 10 ? 2.7 0.0 0.68 4.1e+02 7 31 .. 455 479 .. 451 484 .. 0.85 11 ? 3.8 0.0 0.29 1.8e+02 6 31 .. 494 519 .. 490 525 .. 0.84 12 ! 8.7 0.0 0.0081 4.9 6 31 .. 534 559 .. 530 563 .. 0.88 13 ! 8.8 0.0 0.0071 4.3 5 31 .. 573 599 .. 570 604 .. 0.86 14 ? 2.9 0.0 0.57 3.4e+02 5 25 .. 613 633 .. 610 634 .. 0.85 15 ? 6.8 0.0 0.031 19 6 31 .. 654 679 .. 650 684 .. 0.86 16 ? 5.8 0.0 0.069 42 6 31 .. 694 719 .. 690 724 .. 0.86 17 ? 5.6 0.0 0.081 49 6 29 .. 734 757 .. 730 759 .. 0.88 18 ? 5.8 0.0 0.065 40 6 31 .. 774 799 .. 770 804 .. 0.85 19 ! 8.4 0.0 0.0097 5.9 6 30 .. 814 838 .. 810 841 .. 0.90 20 ? -0.0 0.0 5.1 3.1e+03 9 31 .. 857 879 .. 853 890 .. 0.67 21 ? 3.3 0.1 0.44 2.7e+02 10 41 .. 910 942 .. 908 944 .. 0.75 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 3.7 TPR_14 5 lalarallalGdpdeAlellerala 29 + la+a+ lGd+ +A+++ e+ l+ FUN_002341-T1 53 QNLAYAFPSLGDFRKAIKYHEKHLE 77 5677777789*********998876 PP == domain 2 score: 5.6 bits; conditional E-value: 0.076 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ l+ FUN_002341-T1 94 NLGNAYQSLGDFRKAIEYHEKHLE 117 689***************998876 PP == domain 3 score: 4.6 bits; conditional E-value: 0.16 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a+ lGd+ +A+e+ e+ + FUN_002341-T1 173 GSLGNAYQLLGDFRKAIEYHEKHFK 197 5799**************9988765 PP == domain 4 score: 6.7 bits; conditional E-value: 0.035 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ l ++ +A+e++e++l+ FUN_002341-T1 214 NLGNAYQSLCNFRKAIEYYEKCLEI 238 6899******************986 PP == domain 5 score: 5.7 bits; conditional E-value: 0.075 TPR_14 7 larallalGdpdeAlelleralald 31 l+ a+ lGd+++A+e+ e+ l+l FUN_002341-T1 255 LGIAYQSLGDFQKAIEYHEKHLELA 279 7889***************999876 PP == domain 6 score: 2.7 bits; conditional E-value: 0.68 TPR_14 7 larallalGdpdeAlelleralald 31 l++ + lGd+ +A+e+ e+ l+ FUN_002341-T1 295 LGNDYQSLGDFRKAIEYHEKHLEIA 319 6778999**********99998865 PP == domain 7 score: 2.4 bits; conditional E-value: 0.83 TPR_14 6 alarallalGdpdeAlelleralald 31 l++ + lGd+ +A+e+ e+ l+ FUN_002341-T1 334 SLGDDYQLLGDFRKAIEYHEKHLEIA 359 57788999**********99998865 PP == domain 8 score: 6.8 bits; conditional E-value: 0.033 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ l ++ +A+e++e++l+ FUN_002341-T1 374 SLGNAYQSLCNFRKAIEYYEKCLEI 398 6899******************986 PP == domain 9 score: 5.3 bits; conditional E-value: 0.095 TPR_14 7 larallalGdpdeAlelleralald 31 l+ a+ lGd+++A+e+ e+ l+l FUN_002341-T1 415 LGIAYQSLGDFQKAIEYHEKHLELA 439 67899**************999876 PP == domain 10 score: 2.7 bits; conditional E-value: 0.68 TPR_14 7 larallalGdpdeAlelleralald 31 l++ + lGd+ +A+e+ e+ l+ FUN_002341-T1 455 LGNDYQSLGDFRKAIEYHEKHLEIA 479 6778999**********99998865 PP == domain 11 score: 3.8 bits; conditional E-value: 0.29 TPR_14 6 alarallalGdpdeAlelleralald 31 l++ + lGd+ +A+e+ e+ l+ FUN_002341-T1 494 SLGNGYQSLGDFRKAIEYHEKHLEIA 519 6889999************9999865 PP == domain 12 score: 8.7 bits; conditional E-value: 0.0081 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a++ lGd+ +A+e+ e+ l+l FUN_002341-T1 534 HLGNAYRSLGDFRKAIEYHEKHLELA 559 699*****************999876 PP == domain 13 score: 8.8 bits; conditional E-value: 0.0071 TPR_14 5 lalarallalGdpdeAlelleralald 31 l++a++ lGd+ +A+e+ e+ l+ FUN_002341-T1 573 GSLGNAYWSLGDFRKAIEYHEKHLEIA 599 5799***************99998865 PP == domain 14 score: 2.9 bits; conditional E-value: 0.57 TPR_14 5 lalarallalGdpdeAlelle 25 l++a+ lG++++A+e+ e FUN_002341-T1 613 GSLGNAYQSLGHFQKAIEYHE 633 5799*************9866 PP == domain 15 score: 6.8 bits; conditional E-value: 0.031 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+++A+e+ e+ l+ FUN_002341-T1 654 NLGNAYQSLGDFQKAIEYHEKHLEIA 679 589***************99998865 PP == domain 16 score: 5.8 bits; conditional E-value: 0.069 TPR_14 6 alarallalGdpdeAlelleralald 31 l+ a+ lGd+++A+e+ e+ l+l FUN_002341-T1 694 NLGIAYQSLGDFQKAIEYHEKHLELA 719 58889***************999876 PP == domain 17 score: 5.6 bits; conditional E-value: 0.081 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ e+ l+ FUN_002341-T1 734 CLGSAYQSLGDFRKAIEYHEKRLE 757 6899**************999887 PP == domain 18 score: 5.8 bits; conditional E-value: 0.065 TPR_14 6 alarallalGdpdeAlelleralald 31 l+ a+ lGd+++A+e+ e+ l+l FUN_002341-T1 774 NLGIAYQSLGDFQKAIEYHEKHLELA 799 58889***************999876 PP == domain 19 score: 8.4 bits; conditional E-value: 0.0097 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a+ lGd+ +A+e+ e++l+ FUN_002341-T1 814 CLGNAYQSLGDFRKAIEYHEKCLKI 838 699*******************986 PP == domain 20 score: -0.0 bits; conditional E-value: 5.1 TPR_14 9 rallalGdpdeAlelleralald 31 + ++ lG+++ Al+ + +a++ + FUN_002341-T1 857 QGYFSLGQFENALDKFISAVKVF 879 55667777777776666665554 PP == domain 21 score: 3.3 bits; conditional E-value: 0.44 TPR_14 10 allalGdpdeAlelleralal.dPddpeawlal 41 ll+ G+ deAl +++++ a+ d+ +++++l FUN_002341-T1 910 SLLRIGKIDEALFAADEGRAQtLSDNLWIQYKL 942 6899**************776234555555555 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.1 0.1 62 46 78 .. 12 44 .. 5 46 .. 0.90 2 ? 3.5 0.1 0.17 1.1e+02 24 75 .. 27 81 .. 26 84 .. 0.78 3 ? 5.7 0.1 0.035 21 46 76 .. 92 122 .. 82 125 .. 0.88 4 ? 1.4 0.0 0.82 5e+02 46 76 .. 132 162 .. 123 165 .. 0.87 5 ? 5.3 0.0 0.048 29 47 78 .. 173 204 .. 165 206 .. 0.89 6 ! 7.8 0.1 0.0078 4.7 31 78 .. 197 244 .. 184 245 .. 0.91 7 ! 9.1 0.1 0.0032 1.9 24 78 .. 227 284 .. 218 286 .. 0.82 8 ! 7.8 0.0 0.0081 4.9 36 78 .. 282 324 .. 280 326 .. 0.86 9 ? 7.4 0.0 0.01 6.3 35 78 .. 321 364 .. 320 366 .. 0.90 10 ? 4.8 0.0 0.07 43 34 78 .. 360 404 .. 356 406 .. 0.90 11 ! 9.4 0.1 0.0025 1.5 23 78 .. 386 444 .. 376 446 .. 0.82 12 ? 6.6 0.0 0.018 11 46 78 .. 452 484 .. 443 486 .. 0.84 13 ! 10.8 0.1 0.0009 0.55 33 78 .. 479 524 .. 475 525 .. 0.92 14 ? 5.8 0.1 0.034 21 47 76 .. 533 562 .. 529 566 .. 0.92 15 ! 8.8 0.0 0.0039 2.4 45 78 .. 571 604 .. 560 606 .. 0.88 16 ! 12.1 0.1 0.00036 0.22 35 78 .. 601 644 .. 600 646 .. 0.93 17 ! 9.3 0.1 0.0026 1.6 36 78 .. 642 684 .. 640 687 .. 0.89 18 ? 4.9 0.1 0.064 39 39 76 .. 685 722 .. 682 725 .. 0.84 19 ! 10.1 0.0 0.0015 0.93 37 76 .. 723 762 .. 720 766 .. 0.86 20 ? 5.0 0.1 0.061 37 46 78 .. 772 804 .. 763 806 .. 0.88 21 ! 8.0 0.0 0.0067 4.1 35 75 .. 801 841 .. 800 845 .. 0.86 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.1 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 Gy+ a G ++ a+e+ + l ++ el d FUN_002341-T1 12 YGYISIAFHSKGYFRKAIEYHEKHLKVTMELGD 44 6999999999******************99976 PP == domain 2 score: 3.5 bits; conditional E-value: 0.17 Rapsyn_N 24 kalrvWrkvlkktsdredkf.rllGy..litahsemGkykealefslaqlniaee 75 ka+ k lk t + +d+ + Gy l a +G ++ a+++ + l+ia e FUN_002341-T1 27 KAIEYHEKHLKVTMELGDCAgEEKGYqnLAYAFPSLGDFRKAIKYHEKHLEIAIE 81 67777788888888888886334555337788899***************99977 PP == domain 3 score: 5.7 bits; conditional E-value: 0.035 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia e+ FUN_002341-T1 92 YGNLGNAYQSLGDFRKAIEYHEKHLEIAIEV 122 688999*********************9886 PP == domain 4 score: 1.4 bits; conditional E-value: 0.82 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ + ++ a+++ + l+ia e+ FUN_002341-T1 132 YGSLGNAYQSLCDFRKAIKYHEKDLEIAIEV 162 58888999999****************9886 PP == domain 5 score: 5.3 bits; conditional E-value: 0.048 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + + ia+e+ d FUN_002341-T1 173 GSLGNAYQLLGDFRKAIEYHEKHFKIAKEVSD 204 778889999********************976 PP == domain 6 score: 7.8 bits; conditional E-value: 0.0078 Rapsyn_N 31 kvlkktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 k+ k+ sdr + r G l +a+ + ++ a+e+ + l+i +e+ d FUN_002341-T1 197 KIAKEVSDRVGEGRAYGNLGNAYQSLCNFRKAIEYYEKCLEIVKEVSD 244 678999*************************************99876 PP == domain 7 score: 9.1 bits; conditional E-value: 0.0032 Rapsyn_N 24 kalrvWrkvl...kktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 ka+ + k l k+ sdr + G l a+ +G ++ a+e+ + l++a+e+ d FUN_002341-T1 227 KAIEYYEKCLeivKEVSDRVGEGGAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSD 284 55555555432228999999999999*****************************976 PP == domain 8 score: 7.8 bits; conditional E-value: 0.0081 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 sdr + G l + + +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 282 VSDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSD 324 56777777788999999999********************976 PP == domain 9 score: 7.4 bits; conditional E-value: 0.01 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 + sdr + r G l + +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 321 EVSDRVGEGRAYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEVSD 364 678888999999999999999********************976 PP == domain 10 score: 4.8 bits; conditional E-value: 0.07 Rapsyn_N 34 kktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 k+ sdr + G l +a+ + ++ a+e+ + l+i +e+ d FUN_002341-T1 360 KEVSDRVGEGSAYGSLGNAYQSLCNFRKAIEYYEKCLEIVKEVSD 404 7788999999999***************************99876 PP == domain 11 score: 9.4 bits; conditional E-value: 0.0025 Rapsyn_N 23 ekalrvWrkvl...kktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 ka+ + k l k+ sdr + G l a+ +G ++ a+e+ + l++a+e+ d FUN_002341-T1 386 RKAIEYYEKCLeivKEVSDRVGEGGTYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSD 444 566666655432228999999999999*****************************976 PP == domain 12 score: 6.6 bits; conditional E-value: 0.018 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l + + +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 452 YGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSD 484 6777788889********************976 PP == domain 13 score: 10.8 bits; conditional E-value: 0.0009 Rapsyn_N 33 lkktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 k+ sdr + r G l + + +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 479 AKEVSDRVGEGRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEVRD 524 68899999***********************************865 PP == domain 14 score: 5.8 bits; conditional E-value: 0.034 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l++a+e+ FUN_002341-T1 533 GHLGNAYRSLGDFRKAIEYHEKHLELAKEV 562 88999**********************997 PP == domain 15 score: 8.8 bits; conditional E-value: 0.0039 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 571 AYGSLGNAYWSLGDFRKAIEYHEKHLEIAKEVSD 604 5689999************************976 PP == domain 16 score: 12.1 bits; conditional E-value: 0.00036 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 + sdr + r G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 601 EVSDRVGEGRAYGSLGNAYQSLGHFQKAIEYHEKDLEIAKEVSD 644 6789999999*******************************976 PP == domain 17 score: 9.3 bits; conditional E-value: 0.0026 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeeled 78 sdr + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002341-T1 642 VSDRVGEGSAYGNLGNAYQSLGDFQKAIEYHEKHLEIAKEVSD 684 6777778888999***************************976 PP == domain 18 score: 4.9 bits; conditional E-value: 0.064 Rapsyn_N 39 redkfrllGylitahsemGkykealefslaqlniaeel 76 r + + G l a+ +G ++ a+e+ + l++a+e+ FUN_002341-T1 685 RVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 722 5555566788999999********************97 PP == domain 19 score: 10.1 bits; conditional E-value: 0.0015 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeel 76 s+r + G+l a+ +G ++ a+e+ ++l+ia e+ FUN_002341-T1 723 SHRVGEGSAYGCLGSAYQSLGDFRKAIEYHEKRLEIAIEV 762 5566666678**************************9886 PP == domain 20 score: 5.0 bits; conditional E-value: 0.061 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l a+ +G ++ a+e+ + l++a+e+ d FUN_002341-T1 772 YGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSD 804 5778889999********************976 PP == domain 21 score: 8.0 bits; conditional E-value: 0.0067 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaee 75 + sdr + G+l +a+ +G ++ a+e+ + l i e FUN_002341-T1 801 EVSDRVGEGSAYGCLGNAYQSLGDFRKAIEYHEKCLKIDIE 841 567888888899*******************9998888766 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.4 0.0 0.0027 1.6 13 155 .. 61 202 .. 54 206 .. 0.86 2 ! 8.1 0.0 0.0033 2 42 155 .. 171 282 .. 161 285 .. 0.82 3 ! 12.6 0.0 0.00014 0.082 16 155 .. 224 362 .. 218 366 .. 0.81 4 ! 10.8 0.0 0.00049 0.3 14 155 .. 302 442 .. 299 448 .. 0.80 5 ! 13.1 0.0 0.0001 0.061 16 154 .. 384 521 .. 376 525 .. 0.82 6 ! 24.0 0.1 4.8e-08 2.9e-05 14 192 .. 462 640 .. 459 646 .. 0.90 7 ! 14.2 0.2 4.5e-05 0.027 40 137 .. 649 744 .. 615 759 .. 0.50 8 ! 20.5 0.1 5.4e-07 0.00033 13 182 .. 661 830 .. 655 835 .. 0.69 9 ! 11.8 0.0 0.00025 0.15 13 114 .. 741 843 .. 738 882 .. 0.84 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.0027 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+++ ++ L++ e + + + a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ ++++ ++ ++++A++ ++ l FUN_002341-T1 61 SLGDFRKAIKYHEKHLEIAIEAGHRVGeGNAYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYQSLCDFRKAIKYHEKDL 156 56889999999999999999999988779999*************9999999999999999999999999999********************999 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 + a e + + g ++ +l++ + +d+ +A ++ ++ ++++++ FUN_002341-T1 157 EIAIEVGHRV--GEGDAYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEV 202 9999988774..788899999999988888888888888888877766 PP == domain 2 score: 8.1 bits; conditional E-value: 0.0033 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEwnd 137 a+ +lG a++l+gd+ +A + ++ ++a++ + a+ +++ ++ +++A+e y++ l+ ++e + + g+++ l+ + +d FUN_002341-T1 171 AYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEVSDRVGEGRAYGNLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDRV--GEGGAYGNLGIAYQSLGD 264 7789999999999999888877777777777777666788999999999999999999999999999999988884..777888888888888888 PP TPR_MalT 138 LeeAeqhlqqgiqlgrql 155 + +A ++ ++ ++l++++ FUN_002341-T1 265 FQKAIEYHEKHLELAKEV 282 888888888888887765 PP == domain 3 score: 12.6 bits; conditional E-value: 0.00014 TPR_MalT 16 eaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 ++ +a+e+ ++ L++ +e d++ + + a+ +lG a++ +gd+++A + ++ +la++ + ++ ++++ ++ G++++A+e ++ l+ FUN_002341-T1 224 NFRKAIEYYEKCLEIVKEvsDRVGE-GGAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEI 318 6778888888888888763244444.5566**************999999999999999888888999999************************* PP TPR_MalT 110 aqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 a+e + + g ++ +l+d + +d+ +A ++ ++ +++++++ FUN_002341-T1 319 AKEVSDRV--GEGRAYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEV 362 *9998884..777888888888888888888888877777777765 PP == domain 4 score: 10.8 bits; conditional E-value: 0.00049 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ +e +d + a+ +lG ++l+gd+ +A + ++ ++a++ + a+ ++++ ++ +++A+e y++ l+ FUN_002341-T1 302 LGDFRKAIEYHEKHLEIAKEvSDRVGEGRAYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEVSDRVGEGSAYGSLGNAYQSLCNFRKAIEYYEKCLE 397 678888999999999988873344445888899999999999999999998888888888888888899999999999999999999999999999 PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 ++e + + g+ + l+ + +d+ +A ++ ++ ++l++++ FUN_002341-T1 398 IVKEVSDRV--GEGGTYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 442 999988874..677777777777888888888888777777777765 PP == domain 5 score: 13.1 bits; conditional E-value: 0.0001 TPR_MalT 16 eaeeaeelAreALallpe..ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalql 109 ++ +a+e+ ++ L++ +e d++ + + ++ +lG a++ +gd+++A + ++ +la++ + ++ ++++ ++ G++++A+e ++ l+ FUN_002341-T1 384 NFRKAIEYYEKCLEIVKEvsDRVGE-GGTYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEI 478 6778888888888888763244444.55559999999999999999999999999998888888889999999999999999****9999999999 PP TPR_MalT 110 aqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrq 154 a+e + + g ++ +l++ + +d+ +A ++ ++ ++++++ FUN_002341-T1 479 AKEVSDRV--GEGRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKE 521 99999885..78889999999999999999998888888888776 PP == domain 6 score: 24.0 bits; conditional E-value: 4.8e-08 TPR_MalT 14 qgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ +e +d + a+ +lG ++ +gd+ +A + ++ ++a++ + a+ ++++ +r G++++A+e ++ l+ FUN_002341-T1 462 LGDFRKAIEYHEKHLEIAKEvSDRVGEGRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEVRDGVGEGSAYGHLGNAYRSLGDFRKAIEYHEKHLE 557 6899999999999999998733444558999******************999999999999999999***************************** PP TPR_MalT 109 laqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerlar 192 la+e + + g ++ +l++ ++ +d+ +A ++ ++ +++++++ ++ +ay l + ++ G + A ++ ++ ++a+ FUN_002341-T1 558 LAKEVGHRV--GEGNAYGSLGNAYWSLGDFRKAIEYHEKHLEIAKEVsDRVGEGRAYGSLGNAYQSLGHFQKAIEYHEKDLEIAK 640 ****99885..8899*******************************977799999999999999999999999998888777665 PP == domain 7 score: 14.2 bits; conditional E-value: 4.5e-05 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqesklealplvgfllvgladLlyEw 135 ++a+ +lG a++ +gd+++A + ++ ++a++ + a+ ++ ++ G++++A+e ++ l+la+e + + g ++ l+ + FUN_002341-T1 649 GSAYGNLGNAYQSLGDFQKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSHRV--GEGSAYGCLGSAYQSL 742 555566666666666666666655555555555555555555666666666666666666666666666666554442..2223333333333333 PP TPR_MalT 136 nd 137 +d FUN_002341-T1 743 GD 744 33 PP == domain 8 score: 20.5 bits; conditional E-value: 5.4e-07 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++++a+e+ ++ L++ +e +d + a+ +lG a++ +gd+++A + ++ +la++ + a+ +++ ++ G++++A+e ++ l FUN_002341-T1 661 SLGDFQKAIEYHEKHLEIAKEvSDRVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSHRVGEGSAYGCLGSAYQSLGDFRKAIEYHEKRL 756 567777777777777777776333344477778888888888888877777777777777777777777777788888888888888888888888 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAet 182 + a e + + g ++ l+ + +d+ +A ++ ++ ++l++++ ++ ay l + ++ G+ + A + FUN_002341-T1 757 EIAIEVGHRV--GEGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVsDRVGEGSAYGCLGNAYQSLGDFRKAIE 830 8887777664..6667777777777777777777777777777777775556666666666666666666666655 PP == domain 9 score: 11.8 bits; conditional E-value: 0.00025 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ e + + + a+ +lG a++ +gd+++A + ++ +la++ + a+ ++++ ++ G++++A+e ++ l FUN_002341-T1 741 SLGDFRKAIEYHEKRLEIAIEVGHRVGeGNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVGEGSAYGCLGNAYQSLGDFRKAIEYHEKCL 836 568889999999999999988888887799*******************999999999999999999999*********************99999 PP TPR_MalT 108 qlaqesk 114 + e + FUN_002341-T1 837 KIDIEVG 843 8766655 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 0.0 1.1 6.7e+02 15 33 .. 51 69 .. 49 70 .. 0.90 2 ! 8.3 0.1 0.0075 4.6 14 34 .] 90 110 .. 88 110 .. 0.93 3 ? 6.3 0.1 0.032 20 14 34 .] 170 190 .. 168 190 .. 0.93 4 ? -0.0 0.1 3.4 2e+03 15 26 .. 211 222 .. 209 230 .. 0.76 5 ! 8.0 0.1 0.0092 5.6 15 34 .] 251 270 .. 249 270 .. 0.93 6 ? 6.7 0.0 0.024 15 15 34 .] 411 430 .. 409 430 .. 0.92 7 ? 4.1 0.0 0.16 97 15 34 .] 531 550 .. 528 550 .. 0.91 8 ? -1.0 0.0 7.1 4.3e+03 14 33 .. 570 589 .. 569 590 .. 0.87 9 ? 5.2 0.1 0.073 44 15 34 .] 611 630 .. 608 630 .. 0.92 10 ! 9.2 0.1 0.0038 2.3 14 34 .] 650 670 .. 648 670 .. 0.92 11 ! 9.0 0.1 0.0042 2.6 14 34 .] 690 710 .. 688 710 .. 0.93 12 ? 3.9 0.0 0.18 1.1e+02 15 34 .] 731 750 .. 728 750 .. 0.92 13 ! 9.0 0.1 0.0042 2.6 14 34 .] 770 790 .. 768 790 .. 0.93 14 ? 6.0 0.0 0.041 25 15 34 .] 811 830 .. 808 830 .. 0.92 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 1.1 TPR_17 15 ayynLArlllnnGqleeAl 33 y+nLA++ +G++ +A+ FUN_002341-T1 51 GYQNLAYAFPSLGDFRKAI 69 69*************9998 PP == domain 2 score: 8.3 bits; conditional E-value: 0.0075 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKAIE 110 79****************985 PP == domain 3 score: 6.3 bits; conditional E-value: 0.032 TPR_17 14 dayynLArlllnnGqleeAlq 34 day L+++++ +G++ +A++ FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIE 190 89****************985 PP == domain 4 score: -0.0 bits; conditional E-value: 3.4 TPR_17 15 ayynLArlllnn 26 ay nL+++++ + FUN_002341-T1 211 AYGNLGNAYQSL 222 899*****9855 PP == domain 5 score: 8.0 bits; conditional E-value: 0.0092 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay nL+++++ +G++++A++ FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIE 270 89****************85 PP == domain 6 score: 6.7 bits; conditional E-value: 0.024 TPR_17 15 ayynLArlllnnGqleeAlq 34 y nL+++++ +G++++A++ FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIE 430 599***************85 PP == domain 7 score: 4.1 bits; conditional E-value: 0.16 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002341-T1 531 AYGHLGNAYRSLGDFRKAIE 550 8999*************985 PP == domain 8 score: -1.0 bits; conditional E-value: 7.1 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay L++++ +G++ +A+ FUN_002341-T1 570 NAYGSLGNAYWSLGDFRKAI 589 68999*****9999999997 PP == domain 9 score: 5.2 bits; conditional E-value: 0.073 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++++A++ FUN_002341-T1 611 AYGSLGNAYQSLGHFQKAIE 630 899***************85 PP == domain 10 score: 9.2 bits; conditional E-value: 0.0038 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++++A++ FUN_002341-T1 650 SAYGNLGNAYQSLGDFQKAIE 670 59*****************85 PP == domain 11 score: 9.0 bits; conditional E-value: 0.0042 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++++A++ FUN_002341-T1 690 NAYGNLGIAYQSLGDFQKAIE 710 79*****************85 PP == domain 12 score: 3.9 bits; conditional E-value: 0.18 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay +L+ +++ +G++ +A++ FUN_002341-T1 731 AYGCLGSAYQSLGDFRKAIE 750 89***************985 PP == domain 13 score: 9.0 bits; conditional E-value: 0.0042 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++++A++ FUN_002341-T1 770 NAYGNLGIAYQSLGDFQKAIE 790 79*****************85 PP == domain 14 score: 6.0 bits; conditional E-value: 0.041 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay +L+++++ +G++ +A++ FUN_002341-T1 811 AYGCLGNAYQSLGDFRKAIE 830 8****************985 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 2.6 1.6e+03 5 22 .. 54 71 .. 52 72 .. 0.91 2 ? 3.5 0.0 0.32 1.9e+02 5 22 .. 94 111 .. 91 113 .. 0.92 3 ? 2.9 0.0 0.49 3e+02 6 22 .. 175 191 .. 174 193 .. 0.93 4 ? 3.1 0.0 0.43 2.6e+02 6 28 .. 215 237 .. 211 239 .. 0.90 5 ? 4.7 0.0 0.13 82 6 22 .. 255 271 .. 254 273 .. 0.92 6 ? -1.0 0.0 8.8 5.3e+03 6 22 .. 335 351 .. 334 351 .. 0.84 7 ? 2.3 0.0 0.8 4.9e+02 6 28 .. 375 397 .. 374 398 .. 0.87 8 ? 4.7 0.0 0.13 82 6 22 .. 415 431 .. 414 433 .. 0.92 9 ? 3.8 0.0 0.25 1.5e+02 5 22 .. 534 551 .. 531 553 .. 0.92 10 ? 1.3 0.0 1.6 9.5e+02 6 22 .. 575 591 .. 574 593 .. 0.93 11 ? 1.1 0.0 1.9 1.2e+03 6 22 .. 615 631 .. 609 634 .. 0.66 12 ? 4.7 0.1 0.14 84 5 22 .. 654 671 .. 651 673 .. 0.92 13 ? 4.7 0.0 0.13 81 6 22 .. 695 711 .. 693 713 .. 0.93 14 ? 2.5 0.0 0.69 4.2e+02 6 22 .. 735 751 .. 735 753 .. 0.93 15 ? 4.7 0.0 0.13 81 6 22 .. 775 791 .. 773 793 .. 0.93 16 ? 3.8 0.0 0.26 1.6e+02 6 27 .. 815 836 .. 815 838 .. 0.86 17 ? 0.7 0.0 2.5 1.5e+03 6 25 .. 855 874 .. 853 879 .. 0.81 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 2.6 TPR_6 5 klalsylelgdkdeAkaa 22 +la+++ lgd+ +A+++ FUN_002341-T1 54 NLAYAFPSLGDFRKAIKY 71 699************986 PP == domain 2 score: 3.5 bits; conditional E-value: 0.32 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002341-T1 94 NLGNAYQSLGDFRKAIEY 111 599************986 PP == domain 3 score: 2.9 bits; conditional E-value: 0.49 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002341-T1 175 LGNAYQLLGDFRKAIEY 191 799***********986 PP == domain 4 score: 3.1 bits; conditional E-value: 0.43 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 l+ +y+ l ++ +A+++++++++ FUN_002341-T1 215 LGNAYQSLCNFRKAIEYYEKCLE 237 8999999999**********986 PP == domain 5 score: 4.7 bits; conditional E-value: 0.13 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002341-T1 255 LGIAYQSLGDFQKAIEY 271 89************986 PP == domain 6 score: -1.0 bits; conditional E-value: 8.8 TPR_6 6 lalsylelgdkdeAkaa 22 l++ y+ lgd+ +A+++ FUN_002341-T1 335 LGDDYQLLGDFRKAIEY 351 5677899*******986 PP == domain 7 score: 2.3 bits; conditional E-value: 0.8 TPR_6 6 lalsylelgdkdeAkaalqrlik 28 l+ +y+ l ++ +A+++++++++ FUN_002341-T1 375 LGNAYQSLCNFRKAIEYYEKCLE 397 68888888899*********986 PP == domain 8 score: 4.7 bits; conditional E-value: 0.13 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002341-T1 415 LGIAYQSLGDFQKAIEY 431 89************986 PP == domain 9 score: 3.8 bits; conditional E-value: 0.25 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002341-T1 534 HLGNAYRSLGDFRKAIEY 551 599************986 PP == domain 10 score: 1.3 bits; conditional E-value: 1.6 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002341-T1 575 LGNAYWSLGDFRKAIEY 591 799***********986 PP == domain 11 score: 1.1 bits; conditional E-value: 1.9 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lg +++A+++ FUN_002341-T1 615 LGNAYQSLGHFQKAIEY 631 56677777777777664 PP == domain 12 score: 4.7 bits; conditional E-value: 0.14 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+++A+++ FUN_002341-T1 654 NLGNAYQSLGDFQKAIEY 671 599************986 PP == domain 13 score: 4.7 bits; conditional E-value: 0.13 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002341-T1 695 LGIAYQSLGDFQKAIEY 711 89************986 PP == domain 14 score: 2.5 bits; conditional E-value: 0.69 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002341-T1 735 LGSAYQSLGDFRKAIEY 751 799***********986 PP == domain 15 score: 4.7 bits; conditional E-value: 0.13 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002341-T1 775 LGIAYQSLGDFQKAIEY 791 89************986 PP == domain 16 score: 3.8 bits; conditional E-value: 0.26 TPR_6 6 lalsylelgdkdeAkaalqrli 27 l+ +y+ lgd+ +A+++ ++++ FUN_002341-T1 815 LGNAYQSLGDFRKAIEYHEKCL 836 799************9866665 PP == domain 17 score: 0.7 bits; conditional E-value: 2.5 TPR_6 6 lalsylelgdkdeAkaalqr 25 +++ y+ lg++++A++ + + FUN_002341-T1 855 IGQGYFSLGQFENALDKFIS 874 78889*********998865 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 5.5 3.3e+03 13 31 .. 18 36 .. 16 38 .. 0.85 2 ? 0.1 0.0 2 1.2e+03 13 31 .. 58 76 .. 52 80 .. 0.82 3 ? 1.2 0.0 0.95 5.8e+02 14 31 .. 99 116 .. 96 119 .. 0.89 4 ? 1.0 0.0 1.1 6.6e+02 14 29 .. 179 194 .. 177 199 .. 0.89 5 ? 1.9 0.0 0.55 3.3e+02 12 31 .. 257 276 .. 253 278 .. 0.89 6 ? 0.7 0.0 1.3 8.1e+02 14 31 .. 299 316 .. 298 319 .. 0.88 7 ? 1.6 0.0 0.68 4.1e+02 14 31 .. 339 356 .. 338 359 .. 0.90 8 ? 1.9 0.0 0.55 3.3e+02 12 31 .. 417 436 .. 413 438 .. 0.89 9 ? 0.7 0.0 1.3 8.1e+02 14 31 .. 459 476 .. 458 479 .. 0.88 10 ? 2.4 0.0 0.4 2.4e+02 13 31 .. 498 516 .. 497 519 .. 0.91 11 ? 0.7 0.0 1.4 8.3e+02 14 31 .. 539 556 .. 537 558 .. 0.88 12 ? 0.9 0.0 1.1 6.9e+02 14 31 .. 579 596 .. 577 599 .. 0.88 13 ? -0.8 0.0 3.9 2.4e+03 14 31 .. 619 636 .. 618 638 .. 0.88 14 ? -0.0 0.0 2.3 1.4e+03 14 31 .. 659 676 .. 657 679 .. 0.88 15 ? 1.9 0.0 0.55 3.3e+02 12 31 .. 697 716 .. 693 718 .. 0.89 16 ? 1.2 0.0 0.93 5.6e+02 14 31 .. 739 756 .. 737 759 .. 0.89 17 ? 1.9 0.0 0.55 3.3e+02 12 31 .. 777 796 .. 773 798 .. 0.89 18 ? 1.2 0.0 0.96 5.9e+02 14 32 .. 819 837 .. 817 842 .. 0.85 19 ? 1.6 0.0 0.71 4.3e+02 13 25 .. 858 870 .. 850 878 .. 0.87 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 5.5 DUF2977 13 sYvlvGgledgidvdednl 31 + G ++++i+++e+ l FUN_002341-T1 18 AFHSKGYFRKAIEYHEKHL 36 6777899********9876 PP == domain 2 score: 0.1 bits; conditional E-value: 2 DUF2977 13 sYvlvGgledgidvdednl 31 + G ++++i ++e+ l FUN_002341-T1 58 AFPSLGDFRKAIKYHEKHL 76 56679***********987 PP == domain 3 score: 1.2 bits; conditional E-value: 0.95 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 99 YQSLGDFRKAIEYHEKHL 116 7889***********987 PP == domain 4 score: 1.0 bits; conditional E-value: 1.1 DUF2977 14 YvlvGgledgidvded 29 Y l G ++++i+++e+ FUN_002341-T1 179 YQLLGDFRKAIEYHEK 194 8899**********97 PP == domain 5 score: 1.9 bits; conditional E-value: 0.55 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002341-T1 257 IAYQSLGDFQKAIEYHEKHL 276 8999************9876 PP == domain 6 score: 0.7 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 299 YQSLGDFRKAIEYHEKHL 316 6779***********987 PP == domain 7 score: 1.6 bits; conditional E-value: 0.68 DUF2977 14 YvlvGgledgidvdednl 31 Y l G ++++i+++e+ l FUN_002341-T1 339 YQLLGDFRKAIEYHEKHL 356 7899***********987 PP == domain 8 score: 1.9 bits; conditional E-value: 0.55 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002341-T1 417 IAYQSLGDFQKAIEYHEKHL 436 8999************9876 PP == domain 9 score: 0.7 bits; conditional E-value: 1.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 459 YQSLGDFRKAIEYHEKHL 476 6779***********987 PP == domain 10 score: 2.4 bits; conditional E-value: 0.4 DUF2977 13 sYvlvGgledgidvdednl 31 +Y G ++++i+++e+ l FUN_002341-T1 498 GYQSLGDFRKAIEYHEKHL 516 7999************987 PP == domain 11 score: 0.7 bits; conditional E-value: 1.4 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 539 YRSLGDFRKAIEYHEKHL 556 7789**********9876 PP == domain 12 score: 0.9 bits; conditional E-value: 1.1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 579 YWSLGDFRKAIEYHEKHL 596 7789***********987 PP == domain 13 score: -0.8 bits; conditional E-value: 3.9 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 619 YQSLGHFQKAIEYHEKDL 636 7789**********9876 PP == domain 14 score: -0.0 bits; conditional E-value: 2.3 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 659 YQSLGDFQKAIEYHEKHL 676 7789***********987 PP == domain 15 score: 1.9 bits; conditional E-value: 0.55 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002341-T1 697 IAYQSLGDFQKAIEYHEKHL 716 8999************9876 PP == domain 16 score: 1.2 bits; conditional E-value: 0.93 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002341-T1 739 YQSLGDFRKAIEYHEKRL 756 7889***********987 PP == domain 17 score: 1.9 bits; conditional E-value: 0.55 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002341-T1 777 IAYQSLGDFQKAIEYHEKHL 796 8999************9876 PP == domain 18 score: 1.2 bits; conditional E-value: 0.96 DUF2977 14 YvlvGgledgidvdednlP 32 Y G ++++i+++e+ l FUN_002341-T1 819 YQSLGDFRKAIEYHEKCLK 837 7889***********9875 PP == domain 19 score: 1.6 bits; conditional E-value: 0.71 DUF2977 13 sYvlvGgledgid 25 +Y G++e+++d FUN_002341-T1 858 GYFSLGQFENALD 870 899*********9 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.8 4.9e+02 33 56 .. 93 116 .. 90 121 .. 0.80 2 ? -1.8 0.0 7.8 4.8e+03 36 51 .. 176 191 .. 171 200 .. 0.86 3 ? 1.7 0.0 0.6 3.6e+02 32 58 .. 212 238 .. 208 246 .. 0.84 4 ! 7.7 0.0 0.0081 4.9 32 60 .. 252 280 .. 249 286 .. 0.83 5 ? -1.5 0.0 6.1 3.7e+03 39 60 .. 299 320 .. 295 326 .. 0.80 6 ? 0.4 0.0 1.6 9.5e+02 35 58 .. 375 398 .. 370 406 .. 0.83 7 ! 7.4 0.0 0.01 6.1 33 60 .. 413 440 .. 410 446 .. 0.83 8 ? 0.2 0.0 1.9 1.1e+03 39 51 .. 499 511 .. 455 528 .. 0.56 9 ? 0.2 0.0 1.9 1.1e+03 37 37 .. 530 530 .. 495 564 .. 0.54 10 ? 2.9 0.0 0.26 1.6e+02 35 52 .. 615 632 .. 575 646 .. 0.67 11 ? 4.3 0.0 0.093 57 32 60 .. 652 680 .. 648 686 .. 0.80 12 ? 7.1 0.0 0.012 7.6 33 59 .. 693 719 .. 690 726 .. 0.84 13 ? 1.2 0.0 0.9 5.5e+02 36 51 .. 736 751 .. 731 760 .. 0.85 14 ! 7.6 0.0 0.0089 5.4 33 60 .. 773 800 .. 770 806 .. 0.83 15 ? 1.3 0.0 0.86 5.2e+02 36 58 .. 816 838 .. 812 842 .. 0.86 16 ? -1.9 0.0 8.1 4.9e+03 37 53 .. 857 873 .. 854 878 .. 0.80 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.8 TPR_9 33 rdrGllyaqlgcleaAladLeayl 56 + G +y+ lg++ +A+++ e+ l FUN_002341-T1 93 GNLGNAYQSLGDFRKAIEYHEKHL 116 567999**********99866655 PP == domain 2 score: -1.8 bits; conditional E-value: 7.8 TPR_9 36 GllyaqlgcleaAlad 51 G +y+ lg++ +A+++ FUN_002341-T1 176 GNAYQLLGDFRKAIEY 191 77999********986 PP == domain 3 score: 1.7 bits; conditional E-value: 0.6 TPR_9 32 rrdrGllyaqlgcleaAladLeaylal 58 + + G +y+ l ++ +A+++ e++l++ FUN_002341-T1 212 YGNLGNAYQSLCNFRKAIEYYEKCLEI 238 6678999*****************986 PP == domain 4 score: 7.7 bits; conditional E-value: 0.0081 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalap 60 + + G++y+ lg++++A+++ e+ l+la FUN_002341-T1 252 YGNLGIAYQSLGDFQKAIEYHEKHLELAK 280 5679***************9998888876 PP == domain 5 score: -1.5 bits; conditional E-value: 6.1 TPR_9 39 yaqlgcleaAladLeaylalap 60 y+ lg++ +A+++ e+ l++a FUN_002341-T1 299 YQSLGDFRKAIEYHEKHLEIAK 320 7899******999888887765 PP == domain 6 score: 0.4 bits; conditional E-value: 1.6 TPR_9 35 rGllyaqlgcleaAladLeaylal 58 G +y+ l ++ +A+++ e++l++ FUN_002341-T1 375 LGNAYQSLCNFRKAIEYYEKCLEI 398 57799999*************986 PP == domain 7 score: 7.4 bits; conditional E-value: 0.01 TPR_9 33 rdrGllyaqlgcleaAladLeaylalap 60 + G++y+ lg++++A+++ e+ l+la FUN_002341-T1 413 GNLGIAYQSLGDFQKAIEYHEKHLELAK 440 578***************9998888876 PP == domain 8 score: 0.2 bits; conditional E-value: 1.9 TPR_9 39 yaqlgcleaAlad 51 y+ lg++ +A+++ FUN_002341-T1 499 YQSLGDFRKAIEY 511 5555555555555 PP == domain 9 score: 0.2 bits; conditional E-value: 1.9 TPR_9 37 l 37 + FUN_002341-T1 530 S 530 3 PP == domain 10 score: 2.9 bits; conditional E-value: 0.26 TPR_9 35 rGllyaqlgcleaAladL 52 G +y+ lg++++A+++ FUN_002341-T1 615 LGNAYQSLGHFQKAIEYH 632 466789999999998865 PP == domain 11 score: 4.3 bits; conditional E-value: 0.093 TPR_9 32 rrdrGllyaqlgcleaAladLeaylalap 60 + + G +y+ lg++++A+++ e+ l++a FUN_002341-T1 652 YGNLGNAYQSLGDFQKAIEYHEKHLEIAK 680 5678999***********99888887765 PP == domain 12 score: 7.1 bits; conditional E-value: 0.012 TPR_9 33 rdrGllyaqlgcleaAladLeaylala 59 + G++y+ lg++++A+++ e+ l+la FUN_002341-T1 693 GNLGIAYQSLGDFQKAIEYHEKHLELA 719 678***************988888776 PP == domain 13 score: 1.2 bits; conditional E-value: 0.9 TPR_9 36 GllyaqlgcleaAlad 51 G++y+ lg++ +A+++ FUN_002341-T1 736 GSAYQSLGDFRKAIEY 751 99***********997 PP == domain 14 score: 7.6 bits; conditional E-value: 0.0089 TPR_9 33 rdrGllyaqlgcleaAladLeaylalap 60 + G++y+ lg++++A+++ e+ l+la FUN_002341-T1 773 GNLGIAYQSLGDFQKAIEYHEKHLELAK 800 678***************9998888876 PP == domain 15 score: 1.3 bits; conditional E-value: 0.86 TPR_9 36 GllyaqlgcleaAladLeaylal 58 G +y+ lg++ +A+++ e++l++ FUN_002341-T1 816 GNAYQSLGDFRKAIEYHEKCLKI 838 6789**********998888865 PP == domain 16 score: -1.9 bits; conditional E-value: 8.1 TPR_9 37 llyaqlgcleaAladLe 53 + y+ lg++e Al+ + FUN_002341-T1 857 QGYFSLGQFENALDKFI 873 56899*******99875 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.8 4.7 2.9e+03 15 29 .. 25 39 .. 8 78 .. 0.67 2 ? 2.7 0.0 0.32 2e+02 5 27 .. 95 117 .. 93 122 .. 0.88 3 ? 2.4 0.0 0.4 2.4e+02 5 27 .. 135 157 .. 133 162 .. 0.88 4 ? 3.0 0.0 0.26 1.6e+02 5 30 .. 175 200 .. 173 205 .. 0.88 5 ! 8.1 0.0 0.0067 4.1 5 28 .. 215 238 .. 213 245 .. 0.88 6 ? 1.4 0.0 0.77 4.7e+02 5 28 .. 255 278 .. 253 285 .. 0.83 7 ? 0.2 0.0 1.9 1.1e+03 6 30 .. 296 320 .. 294 325 .. 0.78 8 ? -0.6 0.0 3.2 2e+03 14 30 .. 344 360 .. 334 364 .. 0.78 9 ! 8.0 0.0 0.0076 4.6 5 28 .. 375 398 .. 373 405 .. 0.88 10 ? 1.4 0.0 0.77 4.7e+02 5 28 .. 415 438 .. 413 445 .. 0.83 11 ? 0.2 0.0 1.9 1.1e+03 6 30 .. 456 480 .. 454 485 .. 0.78 12 ? 0.2 0.0 1.9 1.2e+03 6 29 .. 496 519 .. 494 523 .. 0.78 13 ? 1.8 0.1 0.61 3.7e+02 5 27 .. 535 557 .. 533 565 .. 0.86 14 ? 3.0 0.0 0.25 1.5e+02 5 30 .. 575 600 .. 573 606 .. 0.87 15 ? 3.1 0.0 0.23 1.4e+02 5 29 .. 615 639 .. 613 645 .. 0.87 16 ? 4.1 0.0 0.12 70 5 30 .. 655 680 .. 653 685 .. 0.88 17 ? 1.6 0.1 0.68 4.1e+02 5 29 .. 695 719 .. 693 726 .. 0.82 18 ? 1.5 0.0 0.77 4.7e+02 5 27 .. 735 757 .. 734 762 .. 0.87 19 ? 1.4 0.0 0.8 4.9e+02 5 27 .. 775 797 .. 773 804 .. 0.83 20 ? 4.6 0.0 0.083 50 5 29 .. 815 839 .. 814 878 .. 0.83 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 4.7 ARM_TT21_4th 15 YkkAinYYeaalkss 29 ++kAi+Y e+ lk + FUN_002341-T1 25 FRKAIEYHEKHLKVT 39 667777777766643 PP == domain 2 score: 2.7 bits; conditional E-value: 0.32 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002341-T1 95 LGNAYQSLGDFRKAIEYHEKHLE 117 799***************99876 PP == domain 3 score: 2.4 bits; conditional E-value: 0.4 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002341-T1 135 LGNAYQSLCDFRKAIKYHEKDLE 157 799**************998765 PP == domain 4 score: 3.0 bits; conditional E-value: 0.26 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ k+ + FUN_002341-T1 175 LGNAYQLLGDFRKAIEYHEKHFKIAK 200 799999999**********9998766 PP == domain 5 score: 8.1 bits; conditional E-value: 0.0067 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+YYe+ l++ FUN_002341-T1 215 LGNAYQSLCNFRKAIEYYEKCLEI 238 79*****************99876 PP == domain 6 score: 1.4 bits; conditional E-value: 0.77 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G a+ +++kAi+Y e+ l+ FUN_002341-T1 255 LGIAYQSLGDFQKAIEYHEKHLEL 278 6888888999********998765 PP == domain 7 score: 0.2 bits; conditional E-value: 1.9 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalksse 30 G+ + +++kAi+Y e+ l++ + FUN_002341-T1 296 GNDYQSLGDFRKAIEYHEKHLEIAK 320 6666666789********9988765 PP == domain 8 score: -0.6 bits; conditional E-value: 3.2 ARM_TT21_4th 14 qYkkAinYYeaalksse 30 +++kAi+Y e+ l++ + FUN_002341-T1 344 DFRKAIEYHEKHLEIAK 360 799*******9988765 PP == domain 9 score: 8.0 bits; conditional E-value: 0.0076 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+YYe+ l++ FUN_002341-T1 375 LGNAYQSLCNFRKAIEYYEKCLEI 398 799****************99876 PP == domain 10 score: 1.4 bits; conditional E-value: 0.77 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G a+ +++kAi+Y e+ l+ FUN_002341-T1 415 LGIAYQSLGDFQKAIEYHEKHLEL 438 6888888999********998765 PP == domain 11 score: 0.2 bits; conditional E-value: 1.9 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalksse 30 G+ + +++kAi+Y e+ l++ + FUN_002341-T1 456 GNDYQSLGDFRKAIEYHEKHLEIAK 480 6666666789********9988765 PP == domain 12 score: 0.2 bits; conditional E-value: 1.9 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalkss 29 G+ + +++kAi+Y e+ l++ FUN_002341-T1 496 GNGYQSLGDFRKAIEYHEKHLEIA 519 6666667789********998766 PP == domain 13 score: 1.8 bits; conditional E-value: 0.61 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002341-T1 535 LGNAYRSLGDFRKAIEYHEKHLE 557 799999999*********99876 PP == domain 14 score: 3.0 bits; conditional E-value: 0.25 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002341-T1 575 LGNAYWSLGDFRKAIEYHEKHLEIAK 600 799999999**********9988765 PP == domain 15 score: 3.1 bits; conditional E-value: 0.23 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002341-T1 615 LGNAYQSLGHFQKAIEYHEKDLEIA 639 7999*9999**********988765 PP == domain 16 score: 4.1 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002341-T1 655 LGNAYQSLGDFQKAIEYHEKHLEIAK 680 799****************9988765 PP == domain 17 score: 1.6 bits; conditional E-value: 0.68 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G a+ +++kAi+Y e+ l+ FUN_002341-T1 695 LGIAYQSLGDFQKAIEYHEKHLELA 719 6888888999*********988755 PP == domain 18 score: 1.5 bits; conditional E-value: 0.77 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G a+ +++kAi+Y e+ l+ FUN_002341-T1 735 LGSAYQSLGDFRKAIEYHEKRLE 757 699999999*********98776 PP == domain 19 score: 1.4 bits; conditional E-value: 0.8 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G a+ +++kAi+Y e+ l+ FUN_002341-T1 775 LGIAYQSLGDFQKAIEYHEKHLE 797 6888888999********99876 PP == domain 20 score: 4.6 bits; conditional E-value: 0.083 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ lk++ FUN_002341-T1 815 LGNAYQSLGDFRKAIEYHEKCLKID 839 69999999************99976 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 7.6 4.6e+03 19 41 .. 24 46 .. 22 48 .. 0.92 2 ? 3.5 0.1 0.24 1.5e+02 30 53 .. 88 111 .. 54 120 .. 0.61 3 ? 0.4 0.0 2.3 1.4e+03 21 53 .. 157 191 .. 128 195 .. 0.69 4 ? 4.9 0.0 0.089 54 3 58 .. 215 276 .. 214 281 .. 0.76 5 ? 1.2 0.0 1.2 7.4e+02 3 19 .. 295 311 .. 294 314 .. 0.91 6 ? -0.9 0.0 5.8 3.5e+03 3 22 .. 375 394 .. 374 397 .. 0.86 7 ? 1.2 0.0 1.3 7.7e+02 37 53 .. 415 431 .. 412 440 .. 0.58 8 ? 1.2 0.0 1.2 7.4e+02 3 19 .. 455 471 .. 454 474 .. 0.91 9 ? 4.8 0.2 0.093 56 27 56 .. 519 554 .. 487 560 .. 0.59 10 ! 11.3 0.4 0.00088 0.53 3 59 .. 535 597 .. 534 601 .. 0.91 11 ? 7.2 0.3 0.017 10 4 59 .. 609 677 .. 606 683 .. 0.76 12 ? 6.1 0.2 0.037 22 3 58 .. 655 716 .. 654 721 .. 0.77 13 ! 8.3 0.1 0.0073 4.5 3 58 .. 735 796 .. 735 801 .. 0.84 14 ? 1.5 0.0 0.97 5.9e+02 3 19 .. 815 831 .. 815 837 .. 0.90 15 ? 0.4 0.0 2.2 1.4e+03 3 27 .. 855 879 .. 853 886 .. 0.85 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 7.6 TPR_16 19 aleaalrrnPeaaaAllglGlal 41 +++ a++++ + ++lG+++ FUN_002341-T1 24 YFRKAIEYHEKHLKVTMELGDCA 46 7999*****99**********97 PP == domain 2 score: 3.5 bits; conditional E-value: 0.24 TPR_16 30 aaaAllglGlallrqgrlaeAaaa 53 A+ +lG a+ +g++ +A+++ FUN_002341-T1 88 EGNAYGNLGNAYQSLGDFRKAIEY 111 555666666666666666666655 PP == domain 3 score: 0.4 bits; conditional E-value: 2.3 TPR_16 21 eaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 e a++ + +A+ lG a+ +g++ +A+++ FUN_002341-T1 157 EIAIEVGhrVGEGDAYGSLGNAYQLLGDFRKAIEY 191 44555556644667777788888777777777765 PP == domain 4 score: 4.9 bits; conditional E-value: 0.089 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ + +++ A++++e l+ A+ +lG a+ +g++++A+++ ++ l FUN_002341-T1 215 LGNAYQSLCNFRKAIEYYEKCLEIVkevsdrVGEGGAYGNLGIAYQSLGDFQKAIEYHEKHL 276 67777777788888888877777666677775577899999999999999999999866665 PP == domain 5 score: 1.2 bits; conditional E-value: 1.2 TPR_16 3 laraalaagdyddAaaa 19 l++++ +gd++ A+++ FUN_002341-T1 295 LGNDYQSLGDFRKAIEY 311 799***********986 PP == domain 6 score: -0.9 bits; conditional E-value: 5.8 TPR_16 3 laraalaagdyddAaaalea 22 l++a+ + +++ A++++e FUN_002341-T1 375 LGNAYQSLCNFRKAIEYYEK 394 6899999999*******985 PP == domain 7 score: 1.2 bits; conditional E-value: 1.3 TPR_16 37 lGlallrqgrlaeAaaa 53 lG a+ +g++++A+++ FUN_002341-T1 415 LGIAYQSLGDFQKAIEY 431 45555555555555554 PP == domain 8 score: 1.2 bits; conditional E-value: 1.2 TPR_16 3 laraalaagdyddAaaa 19 l++++ +gd++ A+++ FUN_002341-T1 455 LGNDYQSLGDFRKAIEY 471 799***********986 PP == domain 9 score: 4.8 bits; conditional E-value: 0.093 TPR_16 27 n......PeaaaAllglGlallrqgrlaeAaaayra 56 A+ lG a+ +g++ +A+++ ++ FUN_002341-T1 519 AkevrdgVGEGSAYGHLGNAYRSLGDFRKAIEYHEK 554 255556655677888888888888888888877555 PP == domain 10 score: 11.3 bits; conditional E-value: 0.00088 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraalr 59 l++a++ +gd++ A+++ e l+ A+ lG a++ +g++ +A+++ ++ l+ FUN_002341-T1 535 LGNAYRSLGDFRKAIEYHEKHLELAkevghrVGEGNAYGSLGNAYWSLGDFRKAIEYHEKHLE 597 799*********************99*****7799********************99777665 PP == domain 11 score: 7.2 bits; conditional E-value: 0.017 TPR_16 4 araalaagdyddAaaaleaalrrn.............PeaaaAllglGlallrqgrlaeAaaayraalr 59 +ra+ +g+ +++ ++ a++++ A+ +lG a+ +g++++A+++ ++ l+ FUN_002341-T1 609 GRAYGSLGNAYQSLGHFQKAIEYHekdleiakevsdrVGEGSAYGNLGNAYQSLGDFQKAIEYHEKHLE 677 666666666666777777777777777777778888866899*******************99777665 PP == domain 12 score: 6.1 bits; conditional E-value: 0.037 TPR_16 3 laraalaagdyddAaaaleaalrrn......PeaaaAllglGlallrqgrlaeAaaayraal 58 l++a+ +gd++ A+++ e l+ A+ +lG a+ +g++++A+++ ++ l FUN_002341-T1 655 LGNAYQSLGDFQKAIEYHEKHLEIAkevsdrVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHL 716 68888888888888887766555555667786678999999999999999999998866665 PP == domain 13 score: 8.3 bits; conditional E-value: 0.0073 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraal 58 l+ a+ +gd++ A+++ le a++ + A+ +lG a+ +g++++A+++ ++ l FUN_002341-T1 735 LGSAYQSLGDFRKAIEYhekrLEIAIEVGhrVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHL 796 58899999999999864333399999999**7799********************9977666 PP == domain 14 score: 1.5 bits; conditional E-value: 0.97 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002341-T1 815 LGNAYQSLGDFRKAIEY 831 699***********986 PP == domain 15 score: 0.4 bits; conditional E-value: 2.2 TPR_16 3 laraalaagdyddAaaaleaalrrn 27 ++ ++ +g+++ A+ + a++ + FUN_002341-T1 855 IGQGYFSLGQFENALDKFISAVKVF 879 57889999*******9999999876 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.92 5.6e+02 100 126 .. 90 116 .. 28 162 .. 0.56 2 ? 0.2 0.1 0.92 5.6e+02 102 170 .. 92 158 .. 64 206 .. 0.58 3 ? 2.8 0.0 0.15 94 100 172 .. 170 240 .. 143 245 .. 0.71 4 ? 2.1 0.1 0.25 1.5e+02 102 166 .. 212 274 .. 179 284 .. 0.51 5 ? 4.4 0.1 0.05 30 99 171 .. 289 359 .. 257 362 .. 0.63 6 ? 4.6 0.0 0.043 26 83 173 .. 320 401 .. 308 404 .. 0.66 7 ? 6.0 0.0 0.016 9.9 99 173 .. 449 521 .. 418 527 .. 0.73 8 ? 4.8 0.0 0.038 23 77 172 .. 474 560 .. 459 566 .. 0.65 9 ! 8.0 0.1 0.004 2.4 75 172 .. 592 680 .. 577 683 .. 0.62 10 ? 2.0 0.0 0.26 1.6e+02 111 170 .. 694 758 .. 673 763 .. 0.61 11 ? 3.5 0.0 0.092 56 86 169 .. 803 877 .. 775 884 .. 0.45 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.92 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraL 126 + y lG+ + lg +a++ ++ L FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKAIEYHEKHL 116 233333333333333333333333333 PP == domain 2 score: 0.2 bits; conditional E-value: 0.92 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPl.varslhqLagLyaqwgkfstaealykqalei 170 y lG+ + lg +a++ ++ Lei ++ h + ++++ L + y+ f++a +++++ lei FUN_002341-T1 92 YGNLGNAYQSLGDFRKAIEYHEKHLEIA---IEVGHRVgEGNAYGSLGNAYQSLCDFRKAIKYHEKDLEI 158 4455555555555555555555555442...223333312344445555555555555555555555554 PP == domain 3 score: 2.8 bits; conditional E-value: 0.15 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 d y +lG+ + lg +a++ ++ i + D +r++ +L + y+ +f++a ++y++ lei++ FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEV--SDRVGEGRAYGNLGNAYQSLCNFRKAIEYYEKCLEIVK 240 567777777777777777777777777776655..45566677778888888888888888888888888876 PP == domain 4 score: 2.1 bits; conditional E-value: 0.25 TPR_NPHP3 102 yealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykq 166 y lG+ + l +a++ ++ Lei + D + ++ +L y+ g f++a +++++ FUN_002341-T1 212 YGNLGNAYQSLCNFRKAIEYYEKCLEIVKEV--SDRVGEGGAYGNLGIAYQSLGDFQKAIEYHEK 274 3444444444444444444444444443333..23333344444555555555555555555555 PP == domain 5 score: 4.4 bits; conditional E-value: 0.05 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiy 171 ++y +lG+ + lg +a++ ++ Lei + D +r++ L y+ g f++a +++++ lei FUN_002341-T1 289 GSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGRAYGSLGDDYQLLGDFRKAIEYHEKHLEIA 359 4566666666666666677777777777776666..4555667777777777777777777777777777776 PP == domain 6 score: 4.6 bits; conditional E-value: 0.043 TPR_NPHP3 83 kkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 k++ d v++ y +lG + lg +a++ ++ Lei + D ++++ L + y+ +f++a ++y++ lei+++ FUN_002341-T1 320 KEVSDRVGEGRA-------YGSLGDDYQLLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGSLGNAYQSLCNFRKAIEYYEKCLEIVKE 401 444444444444.......4455555555555556666677777777666..456666788889999999999999999999999999865 PP == domain 7 score: 6.0 bits; conditional E-value: 0.016 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 ++y +lG+ + lg +a++ ++ Lei + D +r++ L + y+ g f++a +++++ lei ++ FUN_002341-T1 449 GSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKE 521 5677888888888888888888888888887777..567777889999999999999999999999999988765 PP == domain 8 score: 4.8 bits; conditional E-value: 0.038 TPR_NPHP3 77 aYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 ++l+ +k++ d v++ ++ + y++lG f k + + + L+ a e+R+ + ++++ +L + y g f++a +++++ le+ + FUN_002341-T1 474 KHLEIAKEVSDRVGEGRAYGSLGNGYQSLGDFRKAIEYHE---KHLEIAKEVRDGV------GEGSAYGHLGNAYRSLGDFRKAIEYHEKHLELAK 560 4555566666666666666666666666666666554443...3444555555554......4467788888888888888888888888888765 PP == domain 9 score: 8.0 bits; conditional E-value: 0.004 TPR_NPHP3 75 akaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 +++l+ +k++ d v++ ++ + y++lG+f +a++ ++ Lei + D ++++ +L + y+ g f++a +++++ lei FUN_002341-T1 592 HEKHLEIAKEVSDRVGEGRAYGSLGNAYQSLGHFQ-------KAIEYHEKDLEIAKEV--SDRVGEGSAYGNLGNAYQSLGDFQKAIEYHEKHLEI 678 44555555555555555555555555555555554.......5555566667776655..455566778888999999999999999999988888 PP TPR_NPHP3 171 ye 172 + FUN_002341-T1 679 AK 680 76 PP == domain 10 score: 2.0 bits; conditional E-value: 0.26 TPR_NPHP3 111 dlgllsqalpaLqraLeiRetaldPDhPl...v..arslhqLagLyaqwgkfstaealykqalei 170 +lg+ q+l q+a+e e l+ + + v ++++ L + y+ g f++a +++++ lei FUN_002341-T1 694 NLGIAYQSLGDFQKAIEYHEKHLELAKEVshrVgeGSAYGCLGSAYQSLGDFRKAIEYHEKRLEI 758 56666666666777777766666544333111211234556777777777777777777777766 PP == domain 11 score: 3.5 bits; conditional E-value: 0.092 TPR_NPHP3 86 edavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvar.....slhqLagLyaqwgkfstaealykqale 169 d v++ + +lg q+l ++a+e e l D + r s+h++ + y g+f++a + + a++ FUN_002341-T1 803 SDRVGEGSAYG--------------CLGNAYQSLGDFRKAIEYHEKCLKIDIEVGNRagegiSHHNIGQGYFSLGQFENALDKFISAVK 877 33333333333..............3333444444444444444444444433322211111555555555555555555555555555 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 3.9 2.3e+03 220 243 .. 54 77 .. 47 81 .. 0.87 2 ? 1.3 0.0 0.45 2.7e+02 219 243 .. 93 117 .. 88 120 .. 0.88 3 ? -3.0 0.0 9.1 5.5e+03 219 241 .. 133 155 .. 130 160 .. 0.61 4 ? 4.6 0.0 0.044 27 218 246 .. 172 200 .. 166 204 .. 0.89 5 ? -1.2 0.0 2.5 1.5e+03 219 242 .. 213 236 .. 210 244 .. 0.85 6 ? 0.8 0.0 0.62 3.8e+02 220 243 .. 254 277 .. 250 285 .. 0.85 7 ? -1.4 0.0 2.9 1.8e+03 220 246 .. 294 320 .. 289 323 .. 0.83 8 ? -1.1 0.0 2.3 1.4e+03 221 246 .. 335 360 .. 330 364 .. 0.83 9 ? -0.6 0.0 1.6 1e+03 219 242 .. 373 396 .. 368 404 .. 0.84 10 ? 0.8 0.0 0.62 3.7e+02 220 243 .. 414 437 .. 410 445 .. 0.85 11 ? -1.3 0.0 2.7 1.6e+03 220 246 .. 454 480 .. 449 486 .. 0.83 12 ? 0.9 0.0 0.58 3.5e+02 219 246 .. 493 520 .. 487 524 .. 0.87 13 ? 1.1 0.0 0.5 3e+02 219 243 .. 533 557 .. 528 562 .. 0.85 14 ? 2.9 0.0 0.14 85 219 246 .. 573 600 .. 568 604 .. 0.88 15 ? 0.9 0.0 0.57 3.4e+02 219 244 .. 613 638 .. 608 645 .. 0.67 16 ? 2.8 0.0 0.15 94 219 246 .. 653 680 .. 648 684 .. 0.88 17 ? 0.8 0.0 0.62 3.8e+02 219 243 .. 693 717 .. 689 724 .. 0.86 18 ? 3.7 0.0 0.082 50 218 243 .. 732 757 .. 722 760 .. 0.89 19 ? 0.9 0.0 0.58 3.5e+02 220 244 .. 774 798 .. 770 806 .. 0.85 20 ? 0.2 0.0 0.91 5.5e+02 219 242 .. 813 836 .. 808 840 .. 0.86 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 3.9 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 +A A+ lg+ rkA +y +k+++ FUN_002341-T1 54 NLAYAFPSLGDFRKAIKYHEKHLE 77 68889999************9976 PP == domain 2 score: 1.3 bits; conditional E-value: 0.45 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002341-T1 93 GNLGNAYQSLGDFRKAIEYHEKHLE 117 56899****************9975 PP == domain 3 score: -3.0 bits; conditional E-value: 9.1 TPR_15 219 eayAaAllllgqnrkALpyfrkk 241 + ++ A+ l + rkA +y +k FUN_002341-T1 133 GSLGNAYQSLCDFRKAIKYHEKD 155 44566666677777777766664 PP == domain 4 score: 4.6 bits; conditional E-value: 0.044 TPR_15 218 weayAaAllllgqnrkALpyfrkkaaqnk 246 ++ ++ A+ llg+ rkA +y +k+ + +k FUN_002341-T1 172 YGSLGNAYQLLGDFRKAIEYHEKHFKIAK 200 567999*****************998876 PP == domain 5 score: -1.2 bits; conditional E-value: 2.5 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ l + rkA +y++k + FUN_002341-T1 213 GNLGNAYQSLCNFRKAIEYYEKCL 236 56899***************9965 PP == domain 6 score: 0.8 bits; conditional E-value: 0.62 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ +kA +y +k+++ FUN_002341-T1 254 NLGIAYQSLGDFQKAIEYHEKHLE 277 6788****************9876 PP == domain 7 score: -1.4 bits; conditional E-value: 2.9 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqnk 246 ++ + lg+ rkA +y +k+++ +k FUN_002341-T1 294 SLGNDYQSLGDFRKAIEYHEKHLEIAK 320 56777899************9988765 PP == domain 8 score: -1.1 bits; conditional E-value: 2.3 TPR_15 221 yAaAllllgqnrkALpyfrkkaaqnk 246 ++ + llg+ rkA +y +k+++ +k FUN_002341-T1 335 LGDDYQLLGDFRKAIEYHEKHLEIAK 360 5666899*************988766 PP == domain 9 score: -0.6 bits; conditional E-value: 1.6 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ l + rkA +y++k + FUN_002341-T1 373 GSLGNAYQSLCNFRKAIEYYEKCL 396 67899***************9965 PP == domain 10 score: 0.8 bits; conditional E-value: 0.62 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 ++ A+ lg+ +kA +y +k+++ FUN_002341-T1 414 NLGIAYQSLGDFQKAIEYHEKHLE 437 6889****************9876 PP == domain 11 score: -1.3 bits; conditional E-value: 2.7 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqnk 246 ++ + lg+ rkA +y +k+++ +k FUN_002341-T1 454 SLGNDYQSLGDFRKAIEYHEKHLEIAK 480 56777899************9988765 PP == domain 12 score: 0.9 bits; conditional E-value: 0.58 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ ++ lg+ rkA +y +k+++ +k FUN_002341-T1 493 GSLGNGYQSLGDFRKAIEYHEKHLEIAK 520 678999****************988766 PP == domain 13 score: 1.1 bits; conditional E-value: 0.5 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002341-T1 533 GHLGNAYRSLGDFRKAIEYHEKHLE 557 56899****************9876 PP == domain 14 score: 2.9 bits; conditional E-value: 0.14 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ +k FUN_002341-T1 573 GSLGNAYWSLGDFRKAIEYHEKHLEIAK 600 67899*****************988766 PP == domain 15 score: 0.9 bits; conditional E-value: 0.57 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaq 244 + ++ A+ lg +kA +y +k ++ FUN_002341-T1 613 GSLGNAYQSLGHFQKAIEYHEKDLEI 638 45667777777777777777775554 PP == domain 16 score: 2.8 bits; conditional E-value: 0.15 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ +kA +y +k+++ +k FUN_002341-T1 653 GNLGNAYQSLGDFQKAIEYHEKHLEIAK 680 67899*****************988766 PP == domain 17 score: 0.8 bits; conditional E-value: 0.62 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ +kA +y +k+++ FUN_002341-T1 693 GNLGIAYQSLGDFQKAIEYHEKHLE 717 56889****************9976 PP == domain 18 score: 3.7 bits; conditional E-value: 0.082 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ +++A+ lg+ rkA +y +k+++ FUN_002341-T1 732 YGCLGSAYQSLGDFRKAIEYHEKRLE 757 5789*****************99875 PP == domain 19 score: 0.9 bits; conditional E-value: 0.58 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaq 244 ++ A+ lg+ +kA +y +k+++ FUN_002341-T1 774 NLGIAYQSLGDFQKAIEYHEKHLEL 798 6889****************98764 PP == domain 20 score: 0.2 bits; conditional E-value: 0.91 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ lg+ rkA +y +k + FUN_002341-T1 813 GCLGNAYQSLGDFRKAIEYHEKCL 836 67999**************99865 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.4 0.0 0.86 5.2e+02 24 70 .. 98 147 .. 88 158 .. 0.80 2 ? 3.1 0.0 0.25 1.5e+02 29 66 .. 183 220 .. 170 227 .. 0.83 3 ? -0.8 0.0 3.9 2.4e+03 25 54 .. 219 248 .. 215 277 .. 0.70 4 ? 3.1 0.0 0.25 1.5e+02 26 70 .. 260 307 .. 237 316 .. 0.87 5 ? 2.7 0.0 0.32 1.9e+02 24 60 .. 298 334 .. 293 340 .. 0.86 6 ? 2.1 0.0 0.5 3e+02 30 64 .. 344 381 .. 334 389 .. 0.84 7 ? -0.7 0.0 3.6 2.2e+03 24 54 .. 378 408 .. 363 434 .. 0.74 8 ? 2.9 0.0 0.27 1.7e+02 26 70 .. 420 467 .. 413 475 .. 0.85 9 ? 5.1 0.0 0.06 37 24 70 .. 458 507 .. 454 517 .. 0.81 10 ? 1.1 0.0 1.1 6.5e+02 26 69 .. 500 546 .. 495 558 .. 0.70 11 ? 1.4 0.0 0.83 5.1e+02 25 69 .. 539 586 .. 520 595 .. 0.78 12 ? 3.6 0.0 0.16 1e+02 26 63 .. 580 620 .. 573 626 .. 0.79 13 ? 2.7 0.0 0.32 1.9e+02 26 67 .. 620 664 .. 614 675 .. 0.76 14 ? 0.7 0.0 1.4 8.3e+02 24 61 .. 658 695 .. 651 716 .. 0.78 15 ? -0.9 0.0 4.2 2.6e+03 27 64 .. 701 741 .. 698 757 .. 0.59 16 ? -1.8 0.0 8.3 5e+03 25 53 .. 739 767 .. 714 794 .. 0.76 17 ? 1.3 0.0 0.87 5.3e+02 26 70 .. 780 827 .. 773 836 .. 0.78 Alignments for each domain: == domain 1 score: 1.4 bits; conditional E-value: 0.86 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + +s + ++A+e +e+ e +v ++ sLgn +++ d r+ FUN_002341-T1 98 AYQSLGDFRKAIEYHEKHLEIAIEVGHRVgegNAYGSLGNAYQSLCDFRK 147 57888999********9999999999999443346789999988777666 PP == domain 2 score: 3.1 bits; conditional E-value: 0.25 WH_Halo_primase 29 relydAleaYepereweqkvkneissprsLgnvLkkar 66 + ++A+e +e+ + ++v +++ + r+ gn+ + ++ FUN_002341-T1 183 GDFRKAIEYHEKHFKIAKEVSDRVGEGRAYGNLGNAYQ 220 5899**********************998887655554 PP == domain 3 score: -0.8 bits; conditional E-value: 3.9 WH_Halo_primase 25 fhsarelydAleaYepereweqkvkneiss 54 +s + ++A+e Ye+ e ++v +++ + FUN_002341-T1 219 YQSLCNFRKAIEYYEKCLEIVKEVSDRVGE 248 567778899999999888877777777755 PP == domain 4 score: 3.1 bits; conditional E-value: 0.25 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 +s + +A+e +e+ e ++v +++ s+ sLgn +++ d r+ FUN_002341-T1 260 QSLGDFQKAIEYHEKHLELAKEVSDRVgegSTYGSLGNDYQSLGDFRK 307 6778999********************887788999999998877766 PP == domain 5 score: 2.7 bits; conditional E-value: 0.32 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneissprsLgn 60 +s + ++A+e +e+ e ++v +++ + r+ g FUN_002341-T1 298 DYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGRAYGS 334 5688899**********************99998775 PP == domain 6 score: 2.1 bits; conditional E-value: 0.5 WH_Halo_primase 30 elydAleaYepereweqkvknei...ssprsLgnvLkk 64 + ++A+e +e+ e ++v +++ s sLgn +++ FUN_002341-T1 344 DFRKAIEYHEKHLEIAKEVSDRVgegSAYGSLGNAYQS 381 889********************765557799999887 PP == domain 7 score: -0.7 bits; conditional E-value: 3.6 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss 54 + +s + ++A+e Ye+ e ++v +++ + FUN_002341-T1 378 AYQSLCNFRKAIEYYEKCLEIVKEVSDRVGE 408 5677778899999999888777777777744 PP == domain 8 score: 2.9 bits; conditional E-value: 0.27 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 +s + +A+e +e+ e ++v +++ s+ sLgn +++ d r+ FUN_002341-T1 420 QSLGDFQKAIEYHEKHLELAKEVSDRVgegSTYGSLGNDYQSLGDFRK 467 6778999********************887788999999988877765 PP == domain 9 score: 5.1 bits; conditional E-value: 0.06 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneisspr...sLgnvLkkardhrs 70 +s + ++A+e +e+ e ++v +++ + r sLgn +++ d r+ FUN_002341-T1 458 DYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGRaygSLGNGYQSLGDFRK 507 5688899**********************988744467777777666655 PP == domain 10 score: 1.1 bits; conditional E-value: 1.1 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhr 69 +s + ++A+e +e+ e ++v + + s Lgn +++ d r FUN_002341-T1 500 QSLGDFRKAIEYHEKHLEIAKEVRDGVgegSAYGHLGNAYRSLGDFR 546 67789999999999999999999999944333344566665555544 PP == domain 11 score: 1.4 bits; conditional E-value: 0.83 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhr 69 s + ++A+e +e+ e ++v ++ sLgn + + d r FUN_002341-T1 539 YRSLGDFRKAIEYHEKHLELAKEVGHRVgegNAYGSLGNAYWSLGDFR 586 56778999********99999999999944333678888887766655 PP == domain 12 score: 3.6 bits; conditional E-value: 0.16 WH_Halo_primase 26 hsarelydAleaYepereweqkvkneisspr...sLgnvLk 63 s + ++A+e +e+ e ++v +++ + r sLgn ++ FUN_002341-T1 580 WSLGDFRKAIEYHEKHLEIAKEVSDRVGEGRaygSLGNAYQ 620 577899*********************99883335555554 PP == domain 13 score: 2.7 bits; conditional E-value: 0.32 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkard 67 +s +A+e +e++ e ++v +++ s +Lgn +++ d FUN_002341-T1 620 QSLGHFQKAIEYHEKDLEIAKEVSDRVgegSAYGNLGNAYQSLGD 664 66667789*******************554445677777776555 PP == domain 14 score: 0.7 bits; conditional E-value: 1.4 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneissprsLgnv 61 + +s + +A+e +e+ e ++v +++ + + gn+ FUN_002341-T1 658 AYQSLGDFQKAIEYHEKHLEIAKEVSDRVGEGNAYGNL 695 567888999********999999999999775555554 PP == domain 15 score: -0.9 bits; conditional E-value: 4.2 WH_Halo_primase 27 sarelydAleaYepereweqkvknei...ssprsLgnvLkk 64 s + +A+e +e+ e ++v ++ s Lg +++ FUN_002341-T1 701 SLGDFQKAIEYHEKHLELAKEVSHRVgegSAYGCLGSAYQS 741 66677888888888888888887777332222334444444 PP == domain 16 score: -1.8 bits; conditional E-value: 8.3 WH_Halo_primase 25 fhsarelydAleaYepereweqkvkneis 53 +s + ++A+e +e+ e +v ++ FUN_002341-T1 739 YQSLGDFRKAIEYHEKRLEIAIEVGHRVG 767 56778889999998887666555555554 PP == domain 17 score: 1.3 bits; conditional E-value: 0.87 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 +s + +A+e +e+ e ++v +++ s Lgn +++ d r+ FUN_002341-T1 780 QSLGDFQKAIEYHEKHLELAKEVSDRVgegSAYGCLGNAYQSLGDFRK 827 67778999******9999999999999554445568888887776665 PP >> ARM_CUL7_CUL9 CUL7/CUL9 ARM repeat domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 2.4 1.5e+03 142 164 .. 23 45 .. 18 50 .. 0.85 2 ? -2.3 0.0 9 5.5e+03 145 167 .. 186 208 .. 184 211 .. 0.90 3 ? 2.6 0.0 0.29 1.7e+02 145 167 .. 266 288 .. 262 293 .. 0.89 4 ? 0.8 0.0 1.1 6.4e+02 145 167 .. 306 328 .. 303 332 .. 0.90 5 ? 0.9 0.0 0.99 6e+02 145 167 .. 346 368 .. 343 372 .. 0.89 6 ? 2.6 0.0 0.29 1.7e+02 145 167 .. 426 448 .. 422 453 .. 0.89 7 ? 0.8 0.0 1.1 6.4e+02 145 167 .. 466 488 .. 463 492 .. 0.90 8 ? 4.2 0.0 0.095 58 145 167 .. 506 528 .. 502 532 .. 0.90 9 ? -0.9 0.0 3.5 2.1e+03 145 166 .. 546 567 .. 544 572 .. 0.84 10 ? 0.7 0.0 1.1 6.8e+02 145 167 .. 586 608 .. 584 612 .. 0.90 11 ? 1.0 0.0 0.91 5.5e+02 145 167 .. 626 648 .. 621 652 .. 0.89 12 ? 1.8 0.0 0.51 3.1e+02 145 168 .. 666 689 .. 662 693 .. 0.88 13 ? -0.0 0.0 1.9 1.1e+03 145 166 .. 706 727 .. 703 732 .. 0.86 14 ? 2.4 0.0 0.33 2e+02 145 167 .. 786 808 .. 782 812 .. 0.90 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.4 ARM_CUL7_CUL9 142 eaLskalekhssklllateLrdl 164 ka+e h+++l++ eL d FUN_002341-T1 23 GYFRKAIEYHEKHLKVTMELGDC 45 5678****************986 PP == domain 2 score: -2.3 bits; conditional E-value: 9 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 ka+e h+++ + a+e d v + FUN_002341-T1 186 RKAIEYHEKHFKIAKEVSDRVGE 208 69***************998865 PP == domain 3 score: 2.6 bits; conditional E-value: 0.29 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 +ka+e h+++l+la+e d v + FUN_002341-T1 266 QKAIEYHEKHLELAKEVSDRVGE 288 79*****************9987 PP == domain 4 score: 0.8 bits; conditional E-value: 1.1 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 ka+e h+++l+ a+e d v + FUN_002341-T1 306 RKAIEYHEKHLEIAKEVSDRVGE 328 69****************99876 PP == domain 5 score: 0.9 bits; conditional E-value: 0.99 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 ka+e h+++l+ a+e d v + FUN_002341-T1 346 RKAIEYHEKHLEIAKEVSDRVGE 368 69****************99976 PP == domain 6 score: 2.6 bits; conditional E-value: 0.29 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 +ka+e h+++l+la+e d v + FUN_002341-T1 426 QKAIEYHEKHLELAKEVSDRVGE 448 79*****************9987 PP == domain 7 score: 0.8 bits; conditional E-value: 1.1 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 ka+e h+++l+ a+e d v + FUN_002341-T1 466 RKAIEYHEKHLEIAKEVSDRVGE 488 69****************99876 PP == domain 8 score: 4.2 bits; conditional E-value: 0.095 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 ka+e h+++l+ a+e rd v + FUN_002341-T1 506 RKAIEYHEKHLEIAKEVRDGVGE 528 69*****************9976 PP == domain 9 score: -0.9 bits; conditional E-value: 3.5 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvs 166 ka+e h+++l+la+e + v FUN_002341-T1 546 RKAIEYHEKHLELAKEVGHRVG 567 69*************9877665 PP == domain 10 score: 0.7 bits; conditional E-value: 1.1 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 ka+e h+++l+ a+e d v + FUN_002341-T1 586 RKAIEYHEKHLEIAKEVSDRVGE 608 69****************99876 PP == domain 11 score: 1.0 bits; conditional E-value: 0.91 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 +ka+e h++ l+ a+e d v + FUN_002341-T1 626 QKAIEYHEKDLEIAKEVSDRVGE 648 79****************99976 PP == domain 12 score: 1.8 bits; conditional E-value: 0.51 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsdc 168 +ka+e h+++l+ a+e d v + FUN_002341-T1 666 QKAIEYHEKHLEIAKEVSDRVGEG 689 79*****************99876 PP == domain 13 score: -0.0 bits; conditional E-value: 1.9 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvs 166 +ka+e h+++l+la+e + v FUN_002341-T1 706 QKAIEYHEKHLELAKEVSHRVG 727 79**************987776 PP == domain 14 score: 2.4 bits; conditional E-value: 0.33 ARM_CUL7_CUL9 145 skalekhssklllateLrdlvsd 167 +ka+e h+++l+la+e d v + FUN_002341-T1 786 QKAIEYHEKHLELAKEVSDRVGE 808 79*****************9976 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 0.6 3.6e+02 70 109 .. 75 114 .. 26 130 .. 0.61 2 ? -0.1 0.0 0.65 3.9e+02 70 112 .. 75 117 .. 60 162 .. 0.69 3 ! 7.4 0.1 0.0033 2 84 142 .. 176 235 .. 131 243 .. 0.82 4 ? 4.3 0.0 0.028 17 86 142 .. 258 315 .. 235 326 .. 0.77 5 ! 9.7 0.3 0.00067 0.4 86 248 .. 338 512 .. 330 514 .. 0.70 6 ! 8.9 0.5 0.0012 0.73 87 250 .. 379 554 .. 378 562 .. 0.70 7 ! 7.3 0.1 0.0035 2.1 70 141 .. 595 674 .. 587 684 .. 0.74 8 ? 1.8 0.1 0.17 1e+02 70 140 .. 715 793 .. 705 795 .. 0.64 9 ? 2.7 0.0 0.086 52 87 142 .. 779 835 .. 765 846 .. 0.63 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 0.6 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaek 109 +L++ ea + + + + y l + yq+ g + ka+e ek FUN_002341-T1 75 HLEIAIEAGHRVGEGNAYGNLGNAYQSLGDFRKAIEYHEK 114 3444444444444455555555555555555555554444 PP == domain 2 score: -0.1 bits; conditional E-value: 0.65 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaekkdr 112 +L++ ea + + + + y l + yq+ g + ka+e ek+ FUN_002341-T1 75 HLEIAIEAGHRVGEGNAYGNLGNAYQSLGDFRKAIEYHEKHLE 117 5666666777777777777777777777777777776666543 PP == domain 3 score: 7.4 bits; conditional E-value: 0.0033 TPR_IF140-IFT172 84 ckrydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 + y+ll ++ +a + +k +++a++ +dr+ ++y n + ++ ++++ai++yek+ FUN_002341-T1 176 GNAYQLLGDFRKAIEYHEKHFKIAKEvSDRVGEGRAYGNLGNAYQSLCNFRKAIEYYEKC 235 5689********************8648******************************98 PP == domain 4 score: 4.3 bits; conditional E-value: 0.028 TPR_IF140-IFT172 86 rydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 y+ l ++ +a + +k le+a++ +dr+ +ty + ++ gd+++ai+++ek FUN_002341-T1 258 AYQSLGDFQKAIEYHEKHLELAKEvSDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEKH 315 355666666666666677778765479*************************999985 PP == domain 5 score: 9.7 bits; conditional E-value: 0.00067 TPR_IF140-IFT172 86 rydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aLe.syvkkskdkelkk 174 y+ll ++ +a + +k le+a++ +dr+ ++y + ++ ++++ai++yek+ ev + + + +L +y + + ++ FUN_002341-T1 338 DYQLLGDFRKAIEYHEKHLEIAKEvSDRVGEGSAYGSLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDRVGEGGTygNLGiAYQSLGDFQKAIE 430 699999999999999999999976479999999999999999999999999999999988888887666665441245423444444566667 PP TPR_IF140-IFT172 175 Wwaqylestgele....talkyyeaaedylslvrvlCyledlekaaelanetgdka....acyhlarqyenadeikeaihff 248 + ++le ++e+ + y + +dy sl e ek e+a+e +d+ a l+ y++ +++++ai+++ FUN_002341-T1 431 YHEKHLELAKEVSdrvgEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSDRVgegrAYGSLGNGYQSLGDFRKAIEYH 512 7778887777664111145566677888888877666666666666666665555322226667888888888888888876 PP == domain 6 score: 8.9 bits; conditional E-value: 0.0012 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevPrlLfddte..aL.esyvkkskdkelkkW 175 y+ l ++ +a + ++k le+ ++ +dr+ ty n ++ gd+++ai+++ek ev + + + +L + y + + ++ + FUN_002341-T1 379 YQSLCNFRKAIEYYEKCLEIVKEvSDRVGEGGTYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVGEGSTygSLgNDYQSLGDFRKAIEY 471 777888899999999999986543899999999999999999999999999999998888888876666654322452445555555777777 PP TPR_IF140-IFT172 176 waqylestgele....talkyyeaaedylslvrvlCyledlekaaelanetgd....kaacyhlarqyenadeikeaihfftr 250 ++le ++e+ + + y + + y sl e ek e+a+e +d +a hl+ y + +++++ai+++ + FUN_002341-T1 472 HEKHLEIAKEVSdrvgEGRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEVRDgvgeGSAYGHLGNAYRSLGDFRKAIEYHEK 554 88888777776511114556666777788887666555555555555555444111167888999999999999999999866 PP == domain 7 score: 7.3 bits; conditional E-value: 0.0035 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkale.......vaek.kdrihlrktyynyakhleakgdieeaiklyek 141 +L++ +e + + + + y l + yq+ g+++ka+e +a++ +dr+ ++y n + ++ gd+++ai+++ek FUN_002341-T1 595 HLEIAKEVSDRVGEGRAYGSLGNAYQSLGHFQKAIEyhekdleIAKEvSDRVGEGSAYGNLGNAYQSLGDFQKAIEYHEK 674 56677777777777777777777777777777776511111116654379***9*********************99998 PP == domain 8 score: 1.8 bits; conditional E-value: 0.17 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaekk........drihlrktyynyakhleakgdieeaiklye 140 +L+l +e + + + + y l yq+ g + ka+e ek+ r+ ++y n ++ gd+++ai+++e FUN_002341-T1 715 HLELAKEVSHRVGEGSAYGCLGSAYQSLGDFRKAIEYHEKRleiaievgHRVGEGNAYGNLGIAYQSLGDFQKAIEYHE 793 6788888888888888888888888888888888877665411111111344444555566666666666666666655 PP == domain 9 score: 2.7 bits; conditional E-value: 0.086 TPR_IF140-IFT172 87 ydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeks 142 y+ l ++ +a + +k le+a++ +dr+ ++y + ++ gd+++ai+++ek+ FUN_002341-T1 779 YQSLGDFQKAIEYHEKHLELAKEvSDRVGEGSAYGCLGNAYQSLGDFRKAIEYHEKC 835 555555555555555666666442566666666666666666666666666666665 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.5 0.044 27 45 139 .. 59 153 .. 16 159 .. 0.56 2 ! 13.6 0.1 8.2e-05 0.05 36 180 .. 170 314 .. 167 325 .. 0.86 3 ! 9.5 0.0 0.0014 0.83 43 180 .. 337 474 .. 330 486 .. 0.84 4 ? 2.7 0.1 0.17 1e+02 48 180 .. 462 594 .. 450 606 .. 0.59 5 ? 4.2 0.3 0.058 35 50 179 .. 504 633 .. 490 641 .. 0.60 6 ! 7.9 0.5 0.0044 2.7 38 180 .. 532 674 .. 528 685 .. 0.89 7 ? 5.6 2.6 0.021 13 41 180 .. 615 754 .. 586 761 .. 0.85 8 ? 5.6 0.0 0.022 13 44 147 .. 778 881 .. 769 894 .. 0.88 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.044 SNAP 45 yklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYe 139 + ++++A + ++k e+ +++ + +nay + ++y++ d +A+e ek ei +e g ++ + ++++ y++ d++kAi++ e FUN_002341-T1 59 FPSLGDFRKAIKYHEKHLEIAIEAGHRVGEGNAYGNLGNAYQSLgDFRKAIEYHEKHLEIAIEVGHRVGEGNAYGSLGNAYQSL-CDFRKAIKYHE 153 333344455555555555555555555555555555555555544555555555555555555555555555555555555544.55555555554 PP == domain 2 score: 13.6 bits; conditional E-value: 8.2e-05 SNAP 36 dlykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiyte.kgrfrraAklkkeiaelyekelq 129 d y + +nay+l ++++A e ++k ++ ++++++ ++ay + ++y++ + +A+e +ek+ ei e ++r+ +++ + +++ y++ + FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEVSDRVGEGRAYGNLGNAYQSLcNFRKAIEYYEKCLEIVKEvSDRVGEGG-AYGNLGIAYQSL-G 263 7788889*******************************************997799*************998356666665.567999999977.* PP SNAP 130 dlekAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 d++kAie+ e+ +l ++ + + + + + + +l+++ kAie ek FUN_002341-T1 264 DFQKAIEYHEKHLELAKEVSDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEK 314 ***********9998888777777777888888777888888888887775 PP == domain 3 score: 9.5 bits; conditional E-value: 0.0014 SNAP 43 nayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiyte.kgrfrraAklkkeiaelyekelqdlekAie 136 + y+l ++++A e ++k e+ ++++++ ++ay ++y++ + +A+e +ek+ ei e ++r+ ++++ + +++ y++ +d++kAie FUN_002341-T1 337 DDYQLLGDFRKAIEYHEKHLEIAKEVSDRVGEGSAYGSLGNAYQSLcNFRKAIEYYEKCLEIVKEvSDRVGEGGT-YGNLGIAYQSL-GDFQKAIE 430 679999999**********************************9977999************9883566666665.67999999977.******** PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 + e+ +l ++ + + + + + + +l+++ kAie ek FUN_002341-T1 431 YHEKHLELAKEVSDRVGEGSTYGSLGNDYQSLGDFRKAIEYHEK 474 ***99998888777777777777777777788888888877775 PP == domain 4 score: 2.7 bits; conditional E-value: 0.17 SNAP 48 akkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAa 142 ++++A e ++k e+ ++++++ ++ay + y++ d +A+e ek ei e ++ + ++++ y++ +d++kAie+ e+ FUN_002341-T1 462 LGDFRKAIEYHEKHLEIAKEVSDRVGEGRAYGSLGNGYQSLgDFRKAIEYHEKHLEIAKEVRDGVGEGSAYGHLGNAYRSL-GDFRKAIEYHEKHL 556 555556666666666666666666666666666666665544556666666666666555444444444555666667655.77777777777777 PP SNAP 143 dlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 +l ++ + +++ + + + +l+++ kAie ek FUN_002341-T1 557 ELAKEVGHRVGEGNAYGSLGNAYWSLGDFRKAIEYHEK 594 76666666666666666666666666666666666654 PP == domain 5 score: 4.2 bits; conditional E-value: 0.058 SNAP 50 kwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadl 144 ++++A e ++k e+ +++ + ++ay ++y++ d +A+e ek e+ e g ++ + ++++ y + +d++kAie+ e+ ++ FUN_002341-T1 504 DFRKAIEYHEKHLEIAKEVRDGVGEGSAYGHLGNAYRSLgDFRKAIEYHEKHLELAKEVGHRVGEGNAYGSLGNAYWSL-GDFRKAIEYHEKHLEI 598 5666666666666666666666666666666666666654666666666666666666666666666666666666655.6666666666666666 PP SNAP 145 yeqeeaealankcllkvAdlsaelekyekAieiye 179 ++ + ++ + + + +l++++kAie e FUN_002341-T1 599 AKEVSDRVGEGRAYGSLGNAYQSLGHFQKAIEYHE 633 55555555555556666665666666666665555 PP == domain 6 score: 7.9 bits; conditional E-value: 0.0044 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+ ++++A e ++k e+ ++++ + +nay ++y + d +A+e ek ei e ++ + ++++ y++ ++++ FUN_002341-T1 532 YGHLGNAYRSLGDFRKAIEYHEKHLELAKEVGHRVGEGNAYGSLGNAYWSLgDFRKAIEYHEKHLEIAKEVSDRVGEGRAYGSLGNAYQSL-GHFQ 626 5566899************************************999998866999************9998777777899999*****987.**** PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 kAie+ e+ ++ ++ + +++ ++ + + +l++++kAie ek FUN_002341-T1 627 KAIEYHEKDLEIAKEVSDRVGEGSAYGNLGNAYQSLGDFQKAIEYHEK 674 ***********9999999999999999999999999999999999886 PP == domain 7 score: 5.6 bits; conditional E-value: 0.021 SNAP 41 AAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAi 135 +nay+ ++++A e ++k e+ ++++++ ++ay + ++y++ d ++A+e ek ei e ++ + +++ y++ +d++kAi FUN_002341-T1 615 LGNAYQSLGHFQKAIEYHEKDLEIAKEVSDRVGEGSAYGNLGNAYQSLgDFQKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGIAYQSL-GDFQKAI 709 5789999999999999999999999999999999999999999999877999999999999999998777777778899999999977.9999999 PP SNAP 136 eaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyek 180 e+ e+ +l ++ + +++ + + + +l+++ kAie ek FUN_002341-T1 710 EYHEKHLELAKEVSHRVGEGSAYGCLGSAYQSLGDFRKAIEYHEK 754 999999998888777777778888888888888888888887775 PP == domain 8 score: 5.6 bits; conditional E-value: 0.022 SNAP 44 ayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaY 138 ay+ ++++A e ++k e+ ++++++ ++ay ++y++ d +A+e ek+ +i +e g+ + + +i++ y + +++e+A++++ FUN_002341-T1 778 AYQSLGDFQKAIEYHEKHLELAKEVSDRVGEGSAYGCLGNAYQSLgDFRKAIEYHEKCLKIDIEVGNRAGEGISHHNIGQGYFSL-GQFENALDKF 872 6667778899999999999999999999999999999999998876999******************999999*********987.********** PP SNAP 139 eqAadlyeq 147 A +++++ FUN_002341-T1 873 ISAVKVFNT 881 ***999975 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 7.6 4.6e+03 88 106 .. 90 108 .. 72 111 .. 0.61 2 ? -0.3 0.0 2.8 1.7e+03 76 106 .. 118 148 .. 104 151 .. 0.74 3 ? 0.6 0.0 1.5 9.2e+02 75 107 .. 197 229 .. 183 238 .. 0.80 4 ? 1.6 0.0 0.72 4.4e+02 74 107 .. 274 309 .. 239 311 .. 0.88 5 ? 3.7 0.0 0.16 99 74 107 .. 353 389 .. 312 398 .. 0.79 6 ? 1.4 0.0 0.83 5e+02 75 107 .. 437 469 .. 422 471 .. 0.86 7 ? 2.6 0.0 0.37 2.2e+02 75 107 .. 477 509 .. 468 511 .. 0.88 8 ? 1.5 0.0 0.8 4.9e+02 75 107 .. 517 549 .. 509 551 .. 0.86 9 ? 0.2 0.0 2 1.2e+03 75 107 .. 557 589 .. 549 591 .. 0.84 10 ? 2.1 0.0 0.5 3.1e+02 75 107 .. 597 629 .. 587 631 .. 0.85 11 ? 0.8 0.0 1.3 8e+02 75 107 .. 637 669 .. 627 671 .. 0.82 12 ? 6.2 0.0 0.028 17 75 107 .. 717 749 .. 703 751 .. 0.87 13 ? 7.2 0.0 0.013 8.2 75 108 .. 797 830 .. 778 838 .. 0.86 14 ? 1.1 0.0 1.1 6.6e+02 51 92 .. 1259 1300 .. 1253 1311 .. 0.73 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 7.6 GGDEF_2 88 tvriGvGrpveglaglrrS 106 +++ +G+++++l ++r++ FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKA 108 3444456777777777765 PP == domain 2 score: -0.3 bits; conditional E-value: 2.8 GGDEF_2 76 llerlrrrlggitvriGvGrpveglaglrrS 106 ++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002341-T1 118 IAIEVGHRVGEGNAYGSLGNAYQSLCDFRKA 148 5556666777778888888889988888887 PP == domain 3 score: 0.6 bits; conditional E-value: 1.5 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 ++++++++r+g+ +++ +G+++++l ++r++ FUN_002341-T1 197 KIAKEVSDRVGEGRAYGNLGNAYQSLCNFRKAI 229 788999999999999999999999999999876 PP == domain 4 score: 1.6 bits; conditional E-value: 0.72 GGDEF_2 74 e..ellerlrrrlggitvriGvGrpveglaglrrSy 107 + el++++++r+g+ + + +G+ +++l ++r++ FUN_002341-T1 274 KhlELAKEVSDRVGEGSTYGSLGNDYQSLGDFRKAI 309 145899***************************986 PP == domain 5 score: 3.7 bits; conditional E-value: 0.16 GGDEF_2 74 e...ellerlrrrlggitvriGvGrpveglaglrrSy 107 e e+++++++r+g+ +++ +G+++++l ++r++ FUN_002341-T1 353 EkhlEIAKEVSDRVGEGSAYGSLGNAYQSLCNFRKAI 389 1456999**************************9986 PP == domain 6 score: 1.4 bits; conditional E-value: 0.83 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 el++++++r+g+ + + +G+ +++l ++r++ FUN_002341-T1 437 ELAKEVSDRVGEGSTYGSLGNDYQSLGDFRKAI 469 899***************************986 PP == domain 7 score: 2.6 bits; conditional E-value: 0.37 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+ +++l ++r++ FUN_002341-T1 477 EIAKEVSDRVGEGRAYGSLGNGYQSLGDFRKAI 509 899***************************986 PP == domain 8 score: 1.5 bits; conditional E-value: 0.8 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++r+ +g+ +++ +G+++++l ++r++ FUN_002341-T1 517 EIAKEVRDGVGEGSAYGHLGNAYRSLGDFRKAI 549 789999999999999999************986 PP == domain 9 score: 0.2 bits; conditional E-value: 2 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 el++++ +r+g+ +++ +G+++ +l ++r++ FUN_002341-T1 557 ELAKEVGHRVGEGNAYGSLGNAYWSLGDFRKAI 589 788888899999999999999999999999985 PP == domain 10 score: 2.1 bits; conditional E-value: 0.5 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++ ++ FUN_002341-T1 597 EIAKEVSDRVGEGRAYGSLGNAYQSLGHFQKAI 629 8999999999999999999****9999999875 PP == domain 11 score: 0.8 bits; conditional E-value: 1.3 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++ ++ FUN_002341-T1 637 EIAKEVSDRVGEGSAYGNLGNAYQSLGDFQKAI 669 889999999999999999999999999998875 PP == domain 12 score: 6.2 bits; conditional E-value: 0.028 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 el++++++r+g+ +++ ++G+++++l ++r++ FUN_002341-T1 717 ELAKEVSHRVGEGSAYGCLGSAYQSLGDFRKAI 749 899***************************986 PP == domain 13 score: 7.2 bits; conditional E-value: 0.013 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSyr 108 el++++++r+g+ +++ ++G+++++l ++r++ + FUN_002341-T1 797 ELAKEVSDRVGEGSAYGCLGNAYQSLGDFRKAIE 830 89****************************9975 PP == domain 14 score: 1.1 bits; conditional E-value: 1.1 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvriG 92 +l+a ++ lv+l++ ddea + e+++r+ ++l++ t++++ FUN_002341-T1 1259 AFLAAGARSVLVALWAIDDEA-TMEFMKRFYQHLKDgKTASAA 1300 56777788899*******985.468888888888885444444 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 1.3 8.2e+02 3 20 .. 91 108 .. 89 110 .. 0.89 2 ? 2.4 0.0 0.79 4.8e+02 4 20 .. 172 188 .. 170 190 .. 0.86 3 ? 2.2 0.0 0.87 5.3e+02 3 20 .. 251 268 .. 249 270 .. 0.89 4 ? 1.3 0.0 1.7 1.1e+03 2 20 .. 330 348 .. 329 350 .. 0.89 5 ? 1.3 0.0 1.7 1.1e+03 4 20 .. 412 428 .. 409 430 .. 0.87 6 ? -0.4 0.0 6.3 3.9e+03 3 20 .. 531 548 .. 529 549 .. 0.86 7 ? 2.2 0.0 0.88 5.4e+02 4 20 .. 572 588 .. 570 590 .. 0.86 8 ? 2.0 0.0 1.1 6.4e+02 3 20 .. 651 668 .. 649 670 .. 0.89 9 ? 2.0 0.0 1.1 6.5e+02 3 20 .. 691 708 .. 689 710 .. 0.89 10 ? 2.0 0.0 1.1 6.5e+02 3 20 .. 771 788 .. 769 790 .. 0.89 11 ? -0.2 0.0 5.5 3.4e+03 3 20 .. 811 828 .. 809 829 .. 0.86 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 1.3 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002341-T1 91 AYGNLGNAYQSLGDFRKA 108 6789**********9887 PP == domain 2 score: 2.4 bits; conditional E-value: 0.79 TPR_4 4 llaLArallalGdldeA 20 + L+ a+++lGd+ A FUN_002341-T1 172 YGSLGNAYQLLGDFRKA 188 5679*********9887 PP == domain 3 score: 2.2 bits; conditional E-value: 0.87 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002341-T1 251 AYGNLGIAYQSLGDFQKA 268 7889**********9877 PP == domain 4 score: 1.3 bits; conditional E-value: 1.7 TPR_4 2 rallaLArallalGdldeA 20 ra+ L+ +++lGd+ A FUN_002341-T1 330 RAYGSLGDDYQLLGDFRKA 348 78899**********9887 PP == domain 5 score: 1.3 bits; conditional E-value: 1.7 TPR_4 4 llaLArallalGdldeA 20 + +L+ a++ lGd+ A FUN_002341-T1 412 YGNLGIAYQSLGDFQKA 428 679**********9877 PP == domain 6 score: -0.4 bits; conditional E-value: 6.3 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a+ lGd+ A FUN_002341-T1 531 AYGHLGNAYRSLGDFRKA 548 67889*********9877 PP == domain 7 score: 2.2 bits; conditional E-value: 0.88 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002341-T1 572 YGSLGNAYWSLGDFRKA 588 5679*********9887 PP == domain 8 score: 2.0 bits; conditional E-value: 1.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002341-T1 651 AYGNLGNAYQSLGDFQKA 668 789***********9877 PP == domain 9 score: 2.0 bits; conditional E-value: 1.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002341-T1 691 AYGNLGIAYQSLGDFQKA 708 6789**********9877 PP == domain 10 score: 2.0 bits; conditional E-value: 1.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002341-T1 771 AYGNLGIAYQSLGDFQKA 788 6789**********9877 PP == domain 11 score: -0.2 bits; conditional E-value: 5.5 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a++ lGd+ A FUN_002341-T1 811 AYGCLGNAYQSLGDFRKA 828 67789*********9877 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 0.49 3e+02 3 24 .. 92 113 .. 91 114 .. 0.87 2 ? -1.3 0.0 8.2 5e+03 3 24 .. 132 153 .. 131 154 .. 0.88 3 ? 2.8 0.0 0.41 2.5e+02 2 24 .. 171 193 .. 170 194 .. 0.90 4 ? 0.1 0.1 3 1.8e+03 3 26 .. 212 235 .. 210 238 .. 0.84 5 ? -0.2 0.0 3.5 2.1e+03 8 24 .. 257 273 .. 251 274 .. 0.79 6 ? 1.8 0.0 0.81 4.9e+02 2 24 .. 291 313 .. 290 314 .. 0.90 7 ? 2.1 0.1 0.68 4.2e+02 2 26 .. 371 395 .. 370 398 .. 0.89 8 ? 1.1 0.0 1.4 8.5e+02 2 24 .. 411 433 .. 410 434 .. 0.87 9 ? 1.8 0.0 0.81 4.9e+02 2 24 .. 451 473 .. 450 474 .. 0.90 10 ? 5.2 0.0 0.067 41 2 24 .. 491 513 .. 490 514 .. 0.91 11 ? 4.0 0.0 0.17 1e+02 2 24 .. 531 553 .. 530 554 .. 0.87 12 ? 5.8 0.1 0.045 27 3 24 .. 572 593 .. 571 594 .. 0.91 13 ? 3.0 0.0 0.33 2e+02 2 24 .. 611 633 .. 610 634 .. 0.91 14 ? 2.8 0.0 0.39 2.4e+02 2 24 .. 651 673 .. 650 674 .. 0.88 15 ? -0.2 0.0 3.5 2.1e+03 8 24 .. 697 713 .. 691 714 .. 0.79 16 ? 3.7 0.0 0.2 1.2e+02 2 24 .. 731 753 .. 730 754 .. 0.90 17 ? -0.2 0.0 3.5 2.1e+03 8 24 .. 777 793 .. 771 794 .. 0.79 18 ? 5.3 0.0 0.063 38 2 28 .. 811 837 .. 810 840 .. 0.87 19 ? -0.2 0.0 3.6 2.2e+03 8 23 .. 857 872 .. 855 877 .. 0.88 20 ? -0.3 0.0 3.9 2.3e+03 2 20 .. 903 921 .. 902 922 .. 0.88 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 0.49 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002341-T1 92 YGNLGNAYQSLGDFRKAIEYHE 113 777889*************987 PP == domain 2 score: -1.3 bits; conditional E-value: 8.2 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + ++++A+++++ FUN_002341-T1 132 YGSLGNAYQSLCDFRKAIKYHE 153 889999999999*****99887 PP == domain 3 score: 2.8 bits; conditional E-value: 0.41 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y G++++A+e+++ FUN_002341-T1 171 AYGSLGNAYQLLGDFRKAIEYHE 193 699999**************987 PP == domain 4 score: 0.1 bits; conditional E-value: 3 PPR 3 ynslIsgycknGkleeAlelfkeM 26 y l ++y + ++++A+e++++ FUN_002341-T1 212 YGNLGNAYQSLCNFRKAIEYYEKC 235 7778899999999*******9985 PP == domain 5 score: -0.2 bits; conditional E-value: 3.5 PPR 8 sgycknGkleeAlelfk 24 +y + G++++A+e+++ FUN_002341-T1 257 IAYQSLGDFQKAIEYHE 273 588899********987 PP == domain 6 score: 1.8 bits; conditional E-value: 0.81 PPR 2 tynslIsgycknGkleeAlelfk 24 ty sl + y + G++++A+e+++ FUN_002341-T1 291 TYGSLGNDYQSLGDFRKAIEYHE 313 9999999999**********987 PP == domain 7 score: 2.1 bits; conditional E-value: 0.68 PPR 2 tynslIsgycknGkleeAlelfkeM 26 +y sl ++y + ++++A+e++++ FUN_002341-T1 371 AYGSLGNAYQSLCNFRKAIEYYEKC 395 699999****************985 PP == domain 8 score: 1.1 bits; conditional E-value: 1.4 PPR 2 tynslIsgycknGkleeAlelfk 24 ty l +y + G++++A+e+++ FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHE 433 78888889999*********987 PP == domain 9 score: 1.8 bits; conditional E-value: 0.81 PPR 2 tynslIsgycknGkleeAlelfk 24 ty sl + y + G++++A+e+++ FUN_002341-T1 451 TYGSLGNDYQSLGDFRKAIEYHE 473 9999999999**********987 PP == domain 10 score: 5.2 bits; conditional E-value: 0.067 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl +gy + G++++A+e+++ FUN_002341-T1 491 AYGSLGNGYQSLGDFRKAIEYHE 513 6999****************987 PP == domain 11 score: 4.0 bits; conditional E-value: 0.17 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002341-T1 531 AYGHLGNAYRSLGDFRKAIEYHE 553 5788889*************987 PP == domain 12 score: 5.8 bits; conditional E-value: 0.045 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl ++y + G++++A+e+++ FUN_002341-T1 572 YGSLGNAYWSLGDFRKAIEYHE 593 99999**************987 PP == domain 13 score: 3.0 bits; conditional E-value: 0.33 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G +++A+e+++ FUN_002341-T1 611 AYGSLGNAYQSLGHFQKAIEYHE 633 699999**************987 PP == domain 14 score: 2.8 bits; conditional E-value: 0.39 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l ++y + G++++A+e+++ FUN_002341-T1 651 AYGNLGNAYQSLGDFQKAIEYHE 673 6888999*************987 PP == domain 15 score: -0.2 bits; conditional E-value: 3.5 PPR 8 sgycknGkleeAlelfk 24 +y + G++++A+e+++ FUN_002341-T1 697 IAYQSLGDFQKAIEYHE 713 588899********987 PP == domain 16 score: 3.7 bits; conditional E-value: 0.2 PPR 2 tynslIsgycknGkleeAlelfk 24 +y +l s+y + G++++A+e+++ FUN_002341-T1 731 AYGCLGSAYQSLGDFRKAIEYHE 753 699999**************987 PP == domain 17 score: -0.2 bits; conditional E-value: 3.5 PPR 8 sgycknGkleeAlelfk 24 +y + G++++A+e+++ FUN_002341-T1 777 IAYQSLGDFQKAIEYHE 793 588899********987 PP == domain 18 score: 5.3 bits; conditional E-value: 0.063 PPR 2 tynslIsgycknGkleeAlelfkeMke 28 +y +l ++y + G++++A+e++++ ++ FUN_002341-T1 811 AYGCLGNAYQSLGDFRKAIEYHEKCLK 837 699999***************998665 PP == domain 19 score: -0.2 bits; conditional E-value: 3.6 PPR 8 sgycknGkleeAlelf 23 +gy + G++e Al+ f FUN_002341-T1 857 QGYFSLGQFENALDKF 872 59**********9865 PP == domain 20 score: -0.3 bits; conditional E-value: 3.9 PPR 2 tynslIsgycknGkleeAl 20 +y ++ +++ + Gk++eAl FUN_002341-T1 903 SYCAMWRSLLRIGKIDEAL 921 6888889999********7 PP >> Sec1 Sec1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 2.7 1.6e+03 301 339 .. 90 128 .. 61 172 .. 0.76 2 ? 1.9 0.0 0.22 1.3e+02 307 371 .. 176 239 .. 164 248 .. 0.75 3 ? 2.2 0.1 0.18 1.1e+02 304 339 .. 253 288 .. 223 324 .. 0.72 4 ? 0.9 0.1 0.44 2.7e+02 300 339 .. 289 328 .. 265 366 .. 0.73 5 ? 0.6 0.0 0.54 3.3e+02 312 339 .. 341 368 .. 300 408 .. 0.60 6 ? 4.1 0.0 0.049 30 270 339 .. 384 448 .. 379 485 .. 0.76 7 ? -0.9 0.0 1.6 9.5e+02 311 339 .. 460 488 .. 449 495 .. 0.90 8 ? -0.0 0.0 0.84 5.1e+02 299 337 .. 524 566 .. 504 577 .. 0.75 9 ? 0.1 0.2 0.79 4.8e+02 306 339 .. 575 608 .. 546 645 .. 0.75 10 ! 6.7 0.1 0.0076 4.6 270 339 .. 624 688 .. 617 723 .. 0.79 11 ? 1.5 0.0 0.29 1.8e+02 309 339 .. 778 808 .. 744 844 .. 0.83 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 2.7 Sec1 301 esiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 + +l ++ ++L+++++ + ++H+++a e+ +++ + FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHRVGE 128 55678889999******************9988777765 PP == domain 2 score: 1.9 bits; conditional E-value: 0.22 Sec1 307 kdfvekLpelqeekkklslHtnlaeellkiikk.rkldellelEqdlatgegdkkqkekklieeli 371 ++ + L+++++ + ++H ++a e+++++ + r + +l++ q+l++ + +k++ +++ +e++ FUN_002341-T1 176 GNAYQLLGDFRKAIEYHEKHFKIAKEVSDRVGEgRAYGNLGNAYQSLCN-F-RKAIEYYEKCLEIV 239 56778899***********************876888999999999963.2.32443443344444 PP == domain 3 score: 2.2 bits; conditional E-value: 0.18 Sec1 304 adlkdfvekLpelqeekkklslHtnlaeellkiikk 339 +l + ++L+++q+ + ++H++la e+++++ + FUN_002341-T1 253 GNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVGE 288 566667789999*****************9999876 PP == domain 4 score: 0.9 bits; conditional E-value: 0.44 Sec1 300 sesiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 ++ l + ++L+++++ + ++H+++a e+++++ + FUN_002341-T1 289 GSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSDRVGE 328 4566666666789999999999999999999999998876 PP == domain 5 score: 0.6 bits; conditional E-value: 0.54 Sec1 312 kLpelqeekkklslHtnlaeellkiikk 339 L+++++ + ++H+++a e+++++ + FUN_002341-T1 341 LLGDFRKAIEYHEKHLEIAKEVSDRVGE 368 3566666666666777777777666655 PP == domain 6 score: 4.1 bits; conditional E-value: 0.049 Sec1 270 nfadvgeklkkklkelkaknaelkrkgakssesiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 nf +++e+ +k l+ k+ ++ + g + + +l + ++L+++q+ + ++H++la e+++++ + FUN_002341-T1 384 NFRKAIEYYEKCLEIVKEVSDRV---G--EGGTYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVGE 448 67777777777777666665222...2..1358899999999***********************99976 PP == domain 7 score: -0.9 bits; conditional E-value: 1.6 Sec1 311 ekLpelqeekkklslHtnlaeellkiikk 339 ++L+++++ + ++H+++a e+++++ + FUN_002341-T1 460 QSLGDFRKAIEYHEKHLEIAKEVSDRVGE 488 6899********************99865 PP == domain 8 score: -0.0 bits; conditional E-value: 0.84 Sec1 299 s....sesiadlkdfvekLpelqeekkklslHtnlaeellkii 337 + + +l ++ ++L+++++ + ++H++la e+ +++ FUN_002341-T1 524 DgvgeGSAYGHLGNAYRSLGDFRKAIEYHEKHLELAKEVGHRV 566 23444667789999**********************9986666 PP == domain 9 score: 0.1 bits; conditional E-value: 0.79 Sec1 306 lkdfvekLpelqeekkklslHtnlaeellkiikk 339 l ++ +L+++++ + ++H+++a e+++++ + FUN_002341-T1 575 LGNAYWSLGDFRKAIEYHEKHLEIAKEVSDRVGE 608 556666899*********************9977 PP == domain 10 score: 6.7 bits; conditional E-value: 0.0076 Sec1 270 nfadvgeklkkklkelkaknaelkrkgakssesiadlkdfvekLpelqeekkklslHtnlaeellkiikk 339 +f++++e+ +k+l+ k+ ++ + + + +l ++ ++L+++q+ + ++H+++a e+++++ + FUN_002341-T1 624 HFQKAIEYHEKDLEIAKEVSDRVGE-----GSAYGNLGNAYQSLGDFQKAIEYHEKHLEIAKEVSDRVGE 688 7777888888888777666622222.....357999******************************9987 PP == domain 11 score: 1.5 bits; conditional E-value: 0.29 Sec1 309 fvekLpelqeekkklslHtnlaeellkiikk 339 + ++L+++q+ + ++H++la e+++++ + FUN_002341-T1 778 AYQSLGDFQKAIEYHEKHLELAKEVSDRVGE 808 6689**********************99976 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 5 3e+03 30 71 .. 3 44 .. 2 47 .. 0.88 2 ? 3.2 0.0 0.14 86 37 73 .. 50 86 .. 46 87 .. 0.91 3 ? 5.4 0.0 0.031 19 38 73 .. 91 126 .. 89 127 .. 0.91 4 ? 1.1 0.0 0.64 3.9e+02 38 72 .. 131 165 .. 129 167 .. 0.88 5 ? -1.3 0.0 3.6 2.2e+03 38 63 .. 171 196 .. 170 206 .. 0.85 6 ? 4.3 0.3 0.066 40 37 65 .. 210 238 .. 187 247 .. 0.84 7 ? 1.2 0.0 0.61 3.7e+02 39 66 .. 252 279 .. 248 287 .. 0.85 8 ? -0.4 0.0 1.8 1.1e+03 39 64 .. 292 317 .. 274 327 .. 0.85 9 ? 0.4 0.1 1 6.3e+02 36 64 .. 329 357 .. 307 367 .. 0.78 10 ? 3.7 0.5 0.1 63 38 97 .. 371 430 .. 353 446 .. 0.67 11 ? -0.0 0.1 1.4 8.6e+02 38 64 .. 451 477 .. 426 487 .. 0.79 12 ? 1.6 0.1 0.46 2.8e+02 24 64 .. 477 517 .. 463 526 .. 0.78 13 ? 4.3 0.3 0.065 39 38 73 .. 531 566 .. 506 567 .. 0.85 14 ? 1.5 0.0 0.47 2.9e+02 38 64 .. 571 597 .. 569 606 .. 0.86 15 ? 0.0 0.1 1.4 8.4e+02 37 61 .. 610 634 .. 593 644 .. 0.81 16 ? 4.4 0.3 0.062 38 35 64 .. 648 677 .. 625 686 .. 0.76 17 ? 3.8 0.1 0.095 58 37 72 .. 690 725 .. 673 728 .. 0.83 18 ? 4.9 0.1 0.043 26 42 105 .. 735 798 .. 729 806 .. 0.74 19 ? 1.9 0.2 0.36 2.2e+02 37 65 .. 810 838 .. 786 847 .. 0.78 20 ? -0.3 0.0 1.7 1.1e+03 40 63 .. 853 876 .. 849 892 .. 0.74 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 5 RPN7 30 lgkeeirraledlaehyakigdlenAlkayerarekttslgh 71 ++k+ei +a+ ++ +++ g +++A+++ e+ ++ t+ lg FUN_002341-T1 3 SVKSEIGNAYGYISIAFHSKGYFRKAIEYHEKHLKVTMELGD 44 6799999999999999****************9999988875 PP == domain 2 score: 3.2 bits; conditional E-value: 0.14 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 +++++la + + gd+++A+k+ e+ +e ++ +gh + FUN_002341-T1 50 KGYQNLAYAFPSLGDFRKAIKYHEKHLEIAIEAGHRV 86 678999999*******************999999975 PP == domain 3 score: 5.4 bits; conditional E-value: 0.031 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ +l++ y + gd+++A+++ e+ +e ++ gh + FUN_002341-T1 91 AYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHRV 126 7889***********************999999875 PP == domain 4 score: 1.1 bits; conditional E-value: 0.64 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ l++ y + +d+++A+k+ e+ +e ++ gh FUN_002341-T1 131 AYGSLGNAYQSLCDFRKAIKYHEKDLEIAIEVGHR 165 677899*****************999998888886 PP == domain 5 score: -1.3 bits; conditional E-value: 3.6 RPN7 38 aledlaehyakigdlenAlkayerar 63 a+ l++ y gd+++A+++ e+ + FUN_002341-T1 171 AYGSLGNAYQLLGDFRKAIEYHEKHF 196 67789999************999865 PP == domain 6 score: 4.3 bits; conditional E-value: 0.066 RPN7 37 raledlaehyakigdlenAlkayerarek 65 ra+ +l++ y + +++++A+++ye+++e FUN_002341-T1 210 RAYGNLGNAYQSLCNFRKAIEYYEKCLEI 238 7899*********************9985 PP == domain 7 score: 1.2 bits; conditional E-value: 0.61 RPN7 39 ledlaehyakigdlenAlkayerarekt 66 + +l+ y + gd+++A+++ e+ +e + FUN_002341-T1 252 YGNLGIAYQSLGDFQKAIEYHEKHLELA 279 6788889**************9988765 PP == domain 8 score: -0.4 bits; conditional E-value: 1.8 RPN7 39 ledlaehyakigdlenAlkayerare 64 + l++ y + gd+++A+++ e+ +e FUN_002341-T1 292 YGSLGNDYQSLGDFRKAIEYHEKHLE 317 56788999************999876 PP == domain 9 score: 0.4 bits; conditional E-value: 1 RPN7 36 rraledlaehyakigdlenAlkayerare 64 ra+ l++ y gd+++A+++ e+ +e FUN_002341-T1 329 GRAYGSLGDDYQLLGDFRKAIEYHEKHLE 357 5789999****************999876 PP == domain 10 score: 3.7 bits; conditional E-value: 0.1 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskyle 97 a+ l++ y + +++++A+++ye+++e + + + + ++gi+++ + +k +e FUN_002341-T1 371 AYGSLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDRVGEGGTYGNLGIAYQSLGDFQKAIE 430 677788899999999999999999988776666655555555555555555555554444 PP == domain 11 score: -0.0 bits; conditional E-value: 1.4 RPN7 38 aledlaehyakigdlenAlkayerare 64 ++ l++ y + gd+++A+++ e+ +e FUN_002341-T1 451 TYGSLGNDYQSLGDFRKAIEYHEKHLE 477 56789999*************999876 PP == domain 12 score: 1.6 bits; conditional E-value: 0.46 RPN7 24 kdakenlgkeeirraledlaehyakigdlenAlkayerare 64 + ake + ra+ l++ y + gd+++A+++ e+ +e FUN_002341-T1 477 EIAKEVSDRVGEGRAYGSLGNGYQSLGDFRKAIEYHEKHLE 517 5555555555556789999****************999776 PP == domain 13 score: 4.3 bits; conditional E-value: 0.065 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ l++ y + gd+++A+++ e+ +e + gh + FUN_002341-T1 531 AYGHLGNAYRSLGDFRKAIEYHEKHLELAKEVGHRV 566 78899**********************999999875 PP == domain 14 score: 1.5 bits; conditional E-value: 0.47 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002341-T1 571 AYGSLGNAYWSLGDFRKAIEYHEKHLE 597 677899***************999876 PP == domain 15 score: 0.0 bits; conditional E-value: 1.4 RPN7 37 raledlaehyakigdlenAlkayer 61 ra+ l++ y + g++++A+++ e+ FUN_002341-T1 610 RAYGSLGNAYQSLGHFQKAIEYHEK 634 78899****************9987 PP == domain 16 score: 4.4 bits; conditional E-value: 0.062 RPN7 35 irraledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002341-T1 648 EGSAYGNLGNAYQSLGDFQKAIEYHEKHLE 677 456899******************999876 PP == domain 17 score: 3.8 bits; conditional E-value: 0.095 RPN7 37 raledlaehyakigdlenAlkayerarekttslghk 72 +a+ +l+ y + gd+++A+++ e+ +e + +h FUN_002341-T1 690 NAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSHR 725 678899999****************99998888776 PP == domain 18 score: 4.9 bits; conditional E-value: 0.043 RPN7 42 laehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekaksliek 105 l+ y + gd+++A+++ e+ +e ++ gh + + ++gi+++ + +k +e ++ +e FUN_002341-T1 735 LGSAYQSLGDFRKAIEYHEKRLEIAIEVGHRVGEGNAYGNLGIAYQSLGDFQKAIEYHEKHLEL 798 7778889999999999999999999999998887777777777777777777777666666655 PP == domain 19 score: 1.9 bits; conditional E-value: 0.36 RPN7 37 raledlaehyakigdlenAlkayerarek 65 a+ l++ y + gd+++A+++ e++++ FUN_002341-T1 810 SAYGCLGNAYQSLGDFRKAIEYHEKCLKI 838 567779999***************99875 PP == domain 20 score: -0.3 bits; conditional E-value: 1.7 RPN7 40 edlaehyakigdlenAlkayerar 63 +++++ y++ g++enAl+ + a+ FUN_002341-T1 853 HNIGQGYFSLGQFENALDKFISAV 876 677778888888888888776655 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.0 6.7 4.1e+03 13 34 .. 24 45 .. 22 46 .. 0.92 2 ? 3.5 0.0 0.21 1.3e+02 5 46 .. 63 110 .. 61 118 .. 0.74 3 ? -0.7 0.0 4.2 2.6e+03 26 46 .. 170 190 .. 166 200 .. 0.84 4 ? 2.7 0.0 0.38 2.3e+02 5 49 .. 183 233 .. 179 238 .. 0.80 5 ? 5.2 0.0 0.061 37 7 46 .. 225 270 .. 223 281 .. 0.88 6 ? 0.6 0.0 1.7 1e+03 5 48 .. 343 392 .. 339 397 .. 0.77 7 ? 2.5 0.0 0.43 2.6e+02 7 46 .. 385 430 .. 384 441 .. 0.78 8 ? 3.2 0.1 0.27 1.6e+02 5 46 .. 503 550 .. 499 561 .. 0.87 9 ? 5.0 0.0 0.073 44 4 47 .. 542 591 .. 539 606 .. 0.87 10 ? 4.1 0.0 0.13 81 3 46 .. 581 630 .. 579 641 .. 0.90 11 ? 7.1 0.1 0.016 9.8 5 46 .. 663 710 .. 659 721 .. 0.91 12 ? 2.5 0.1 0.42 2.6e+02 5 46 .. 743 790 .. 739 802 .. 0.69 13 ? 1.8 0.1 0.72 4.4e+02 5 46 .. 783 830 .. 779 834 .. 0.80 14 ? -0.2 0.0 3 1.8e+03 4 21 .. 822 839 .. 819 839 .. 0.88 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 6.7 TPR_19 13 lLeqalaedPdnaearllLAra 34 ++++a++++ ++ + + L+++ FUN_002341-T1 24 YFRKAIEYHEKHLKVTMELGDC 45 799****************999 PP == domain 2 score: 3.5 bits; conditional E-value: 0.21 TPR_19 5 gdydeAlalLeqalae..dPd....naearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + + a+ +L++a+ lg++ +A++ FUN_002341-T1 63 GDFRKAIKYHEKHLEIaiEAGhrvgEGNAYGNLGNAYQSLGDFRKAIE 110 777777777777554433222355588999****************87 PP == domain 3 score: -0.7 bits; conditional E-value: 4.2 TPR_19 26 earllLArallalgrldeAea 46 +a+ L++a+ lg++ +A++ FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIE 190 778889999999999999986 PP == domain 4 score: 2.7 bits; conditional E-value: 0.38 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAealLa 49 gd+ +A+++ e+ +++ + +a+ +L++a+ l ++ +A++ + FUN_002341-T1 183 GDFRKAIEYHEKHFKIAKEvsdrvgEGRAYGNLGNAYQSLCNFRKAIEYYE 233 7888888888886666555555777999999**************998765 PP == domain 5 score: 5.2 bits; conditional E-value: 0.061 TPR_19 7 ydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 + +A++++e+ l++ + a+ +L+ a+ lg++ +A++ FUN_002341-T1 225 FRKAIEYYEKCLEIVKEvsdrvgEGGAYGNLGIAYQSLGDFQKAIE 270 78999999999999888777888999******************87 PP == domain 6 score: 0.6 bits; conditional E-value: 1.7 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAealL 48 gd+ +A+++ e+ l+++ + a+ L++a+ l ++ +A++ FUN_002341-T1 343 GDFRKAIEYHEKHLEIAKEvsdrvgEGSAYGSLGNAYQSLCNFRKAIEYY 392 88888999888888887776667777778888888888888888888765 PP == domain 7 score: 2.5 bits; conditional E-value: 0.43 TPR_19 7 ydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 + +A++++e+ l++ + + +L+ a+ lg++ +A++ FUN_002341-T1 385 FRKAIEYYEKCLEIVKEvsdrvgEGGTYGNLGIAYQSLGDFQKAIE 430 6788888888888877766666677778899999999999999986 PP == domain 8 score: 3.2 bits; conditional E-value: 0.27 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002341-T1 503 GDFRKAIEYHEKHLEIAKEvrdgvgEGSAYGHLGNAYRSLGDFRKAIE 550 89999999999998888888889999999999***********99987 PP == domain 9 score: 5.0 bits; conditional E-value: 0.073 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002341-T1 542 LGDFRKAIEYHEKHLELAKEvghrvgEGNAYGSLGNAYWSLGDFRKAIEY 591 6999999999999999988888899999*******************985 PP == domain 10 score: 4.1 bits; conditional E-value: 0.13 TPR_19 3 aegdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + +a+ L++a+ lg++ +A++ FUN_002341-T1 581 SLGDFRKAIEYHEKHLEIAKEvsdrvgEGRAYGSLGNAYQSLGHFQKAIE 630 569***********999988888899999******************987 PP == domain 11 score: 7.1 bits; conditional E-value: 0.016 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+++A+++ e+ l+++ + a+ +L+ a+ lg++ +A++ FUN_002341-T1 663 GDFQKAIEYHEKHLEIAKEvsdrvgEGNAYGNLGIAYQSLGDFQKAIE 710 9***********9999999888999*********************97 PP == domain 12 score: 2.5 bits; conditional E-value: 0.42 TPR_19 5 gdydeAlalLeqalae......dPdnaearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + a+ +L+ a+ lg++ +A++ FUN_002341-T1 743 GDFRKAIEYHEKRLEIaievghRVGEGNAYGNLGIAYQSLGDFQKAIE 790 666666666666444422222233477899999999999999999987 PP == domain 13 score: 1.8 bits; conditional E-value: 0.72 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+++A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002341-T1 783 GDFQKAIEYHEKHLELAKEvsdrvgEGSAYGCLGNAYQSLGDFRKAIE 830 999999999999888887776677777777788888888888888876 PP == domain 14 score: -0.2 bits; conditional E-value: 3 TPR_19 4 egdydeAlalLeqalaed 21 gd+ +A+++ e+ l++d FUN_002341-T1 822 LGDFRKAIEYHEKCLKID 839 59***********99876 PP >> Bleomycin_resist_prot_dom Bleomycin resistance protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 9.1 5.5e+03 8 38 .. 104 133 .. 96 149 .. 0.80 2 ? 1.8 0.0 0.76 4.6e+02 9 38 .. 225 253 .. 216 260 .. 0.86 3 ? 1.0 0.0 1.3 8.1e+02 8 39 .. 264 294 .. 256 301 .. 0.82 4 ? -0.9 0.0 5 3.1e+03 8 38 .. 304 333 .. 296 340 .. 0.84 5 ? -0.6 0.0 4.1 2.5e+03 8 38 .. 344 373 .. 336 381 .. 0.84 6 ? 1.9 0.0 0.67 4.1e+02 9 38 .. 385 413 .. 376 422 .. 0.86 7 ? 1.0 0.0 1.3 7.8e+02 8 39 .. 424 454 .. 416 462 .. 0.82 8 ? -1.0 0.0 5.7 3.5e+03 8 34 .. 464 490 .. 456 499 .. 0.84 9 ? -1.2 0.0 6.5 3.9e+03 8 38 .. 544 573 .. 536 579 .. 0.82 10 ? 0.2 0.0 2.3 1.4e+03 7 38 .. 583 613 .. 573 631 .. 0.82 11 ? 0.6 0.0 1.8 1.1e+03 8 35 .. 664 693 .. 656 701 .. 0.80 12 ? 4.5 0.0 0.11 66 8 40 .. 704 735 .. 696 742 .. 0.88 13 ? 4.7 0.0 0.091 55 8 40 .. 784 815 .. 776 822 .. 0.87 14 ? 0.2 0.0 2.3 1.4e+03 8 35 .. 824 851 .. 816 857 .. 0.86 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 9.1 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l ++ r +eG yG FUN_002341-T1 104 DFRKAIEYHEKHLEIAIEVGHRVGEGN-AYG 133 88999********99999999999994.344 PP == domain 2 score: 1.8 bits; conditional E-value: 0.76 Bleomycin_resist_prot_dom 9 mdktlkWfekilGWsGdivarddeGlGdyG 38 k+++++ek l ++ r +eG G yG FUN_002341-T1 225 FRKAIEYYEKCLEIVKEVSDRVGEG-GAYG 253 6799********************9.7777 PP == domain 3 score: 1.0 bits; conditional E-value: 1.3 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyGc 39 d k++++ ek l ++ r +eG yG FUN_002341-T1 264 DFQKAIEYHEKHLELAKEVSDRVGEGS-TYGS 294 899**********************94.4554 PP == domain 4 score: -0.9 bits; conditional E-value: 5 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l ++ r +eG yG FUN_002341-T1 304 DFRKAIEYHEKHLEIAKEVSDRVGEGR-AYG 333 8889*******************9994.344 PP == domain 5 score: -0.6 bits; conditional E-value: 4.1 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l ++ r +eG yG FUN_002341-T1 344 DFRKAIEYHEKHLEIAKEVSDRVGEGS-AYG 373 7889*********************94.354 PP == domain 6 score: 1.9 bits; conditional E-value: 0.67 Bleomycin_resist_prot_dom 9 mdktlkWfekilGWsGdivarddeGlGdyG 38 k+++++ek l ++ r +eG G yG FUN_002341-T1 385 FRKAIEYYEKCLEIVKEVSDRVGEG-GTYG 413 6799********************9.7777 PP == domain 7 score: 1.0 bits; conditional E-value: 1.3 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyGc 39 d k++++ ek l ++ r +eG yG FUN_002341-T1 424 DFQKAIEYHEKHLELAKEVSDRVGEGS-TYGS 454 899**********************94.4554 PP == domain 8 score: -1.0 bits; conditional E-value: 5.7 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGl 34 d k++++ ek l ++ r +eG FUN_002341-T1 464 DFRKAIEYHEKHLEIAKEVSDRVGEGR 490 8889******************99994 PP == domain 9 score: -1.2 bits; conditional E-value: 6.5 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l ++ r +eG yG FUN_002341-T1 544 DFRKAIEYHEKHLELAKEVGHRVGEGN-AYG 573 8899******************99994.344 PP == domain 10 score: 0.2 bits; conditional E-value: 2.3 Bleomycin_resist_prot_dom 7 kdmdktlkWfekilGWsGdivarddeGlGdyG 38 d k++++ ek l ++ r +eG yG FUN_002341-T1 583 GDFRKAIEYHEKHLEIAKEVSDRVGEGR-AYG 613 4899*********************994.344 PP == domain 11 score: 0.6 bits; conditional E-value: 1.8 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeG..lG 35 d k++++ ek l ++ r +eG +G FUN_002341-T1 664 DFQKAIEYHEKHLEIAKEVSDRVGEGnaYG 693 899*******************99993334 PP == domain 12 score: 4.5 bits; conditional E-value: 0.11 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyGcv 40 d k++++ ek l ++ r +eG yGc+ FUN_002341-T1 704 DFQKAIEYHEKHLELAKEVSHRVGEG-SAYGCL 735 899***********************.579*97 PP == domain 13 score: 4.7 bits; conditional E-value: 0.091 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlGdyGcv 40 d k++++ ek l ++ r +eG yGc+ FUN_002341-T1 784 DFQKAIEYHEKHLELAKEVSDRVGEG-SAYGCL 815 899***********************.57***7 PP == domain 14 score: 0.2 bits; conditional E-value: 2.3 Bleomycin_resist_prot_dom 8 dmdktlkWfekilGWsGdivarddeGlG 35 d k++++ ek l ++ r +eG+ FUN_002341-T1 824 DFRKAIEYHEKCLKIDIEVGNRAGEGIS 851 889***********************86 PP >> CODH_A_N Carbon monoxide dehydrogenase subunit alpha N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.5 9.4e+02 30 65 .. 92 127 .. 88 152 .. 0.68 2 ? -1.5 0.0 6.3 3.8e+03 30 59 .. 172 201 .. 168 231 .. 0.67 3 ? -1.0 0.0 4.5 2.7e+03 30 60 .. 252 282 .. 251 294 .. 0.78 4 ? 0.2 0.0 1.8 1.1e+03 30 63 .. 292 325 .. 289 334 .. 0.79 5 ? -0.9 0.0 4.1 2.5e+03 30 63 .. 332 365 .. 328 376 .. 0.73 6 ? -1.2 0.0 5 3e+03 30 59 .. 412 441 .. 411 451 .. 0.78 7 ? 0.8 0.0 1.2 7.1e+02 30 64 .. 452 486 .. 448 532 .. 0.72 8 ? 0.6 0.0 1.3 8.2e+02 30 68 .. 532 570 .. 529 591 .. 0.83 9 ? 0.4 0.0 1.6 9.8e+02 30 66 .. 652 688 .. 649 711 .. 0.76 10 ? -0.5 0.0 3 1.8e+03 30 66 .. 692 728 .. 689 733 .. 0.79 11 ? 0.5 0.0 1.4 8.7e+02 30 67 .. 732 769 .. 729 791 .. 0.81 12 ? -0.6 0.0 3.3 2e+03 30 64 .. 772 806 .. 769 812 .. 0.78 13 ? 2.0 0.0 0.49 3e+02 30 69 .. 812 851 .. 809 855 .. 0.88 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekald 65 y+ +G++ + Lgd +++++ ++ l+ + ++ + FUN_002341-T1 92 YGNLGNAYQSLGDFRKAIEYHEKHLEIAIEVGHRVG 127 555677777777777777777776666665555444 PP == domain 2 score: -1.5 bits; conditional E-value: 6.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G++ + Lgd +++++ ++ +k ++ FUN_002341-T1 172 YGSLGNAYQLLGDFRKAIEYHEKHFKIAKE 201 556677777777777777776666555554 PP == domain 3 score: -1.0 bits; conditional E-value: 4.5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkL 60 y+ +G + + Lgd +++++ ++ l+ ++ FUN_002341-T1 252 YGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 282 6778999999********9999888766654 PP == domain 4 score: 0.2 bits; conditional E-value: 1.8 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLeka 63 y+ +G++ + Lgd +++++ ++ l+ ++ + FUN_002341-T1 292 YGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSDR 325 7889**************9999988777665554 PP == domain 5 score: -0.9 bits; conditional E-value: 4.1 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLeka 63 y+ +G++ + Lgd +++++ ++ l+ ++ + FUN_002341-T1 332 YGSLGDDYQLLGDFRKAIEYHEKHLEIAKEVSDR 365 6778888888888888888888877766665554 PP == domain 6 score: -1.2 bits; conditional E-value: 5 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelk 59 y+ +G + + Lgd +++++ ++ l+ ++ FUN_002341-T1 412 YGNLGIAYQSLGDFQKAIEYHEKHLELAKE 441 6778999999*******9999888776555 PP == domain 7 score: 0.8 bits; conditional E-value: 1.2 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekal 64 y+ +G++ + Lgd +++++ ++ l+ ++ + + FUN_002341-T1 452 YGSLGNDYQSLGDFRKAIEYHEKHLEIAKEVSDRV 486 66778888888888888887777766655544433 PP == domain 8 score: 0.6 bits; conditional E-value: 1.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGm 68 y+ +G++ + Lgd +++++ ++ l+ ++ ++ + G FUN_002341-T1 532 YGHLGNAYRSLGDFRKAIEYHEKHLELAKEVGHRVGEGN 570 778899999999999999999999988888777666665 PP == domain 9 score: 0.4 bits; conditional E-value: 1.6 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekalda 66 y+ +G++ + Lgd +++++ ++ l+ ++ + + FUN_002341-T1 652 YGNLGNAYQSLGDFQKAIEYHEKHLEIAKEVSDRVGE 688 6778999999999999999999888777665444444 PP == domain 10 score: -0.5 bits; conditional E-value: 3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekalda 66 y+ +G + + Lgd +++++ ++ l+ ++ + + FUN_002341-T1 692 YGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSHRVGE 728 677899999*********9999988877766655555 PP == domain 11 score: 0.5 bits; conditional E-value: 1.4 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaG 67 y+++G + + Lgd +++++ ++ l+ + ++ + G FUN_002341-T1 732 YGCLGSAYQSLGDFRKAIEYHEKRLEIAIEVGHRVGEG 769 78899999999999999999999888777766665555 PP == domain 12 score: -0.6 bits; conditional E-value: 3.3 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekal 64 y+ +G + + Lgd +++++ ++ l+ ++ + + FUN_002341-T1 772 YGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRV 806 677899999*********99999888776666555 PP == domain 13 score: 2.0 bits; conditional E-value: 0.49 CODH_A_N 30 yaltGekvktLgdleevLnrarsllkeelkLekaldaGma 69 y+++G++ + Lgd +++++ ++ lk + + ++ G++ FUN_002341-T1 812 YGCLGNAYQSLGDFRKAIEYHEKCLKIDIEVGNRAGEGIS 851 8999********************9999988888777766 PP >> DUF4810 Domain of unknown function (DUF4810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.2 0.22 1.3e+02 6 70 .. 51 114 .. 49 118 .. 0.88 2 ? 5.9 0.0 0.044 27 23 71 .. 226 275 .. 212 285 .. 0.83 3 ? 0.5 0.0 2.1 1.3e+03 22 70 .. 345 394 .. 338 404 .. 0.89 4 ? 5.9 0.0 0.045 27 23 71 .. 386 435 .. 373 444 .. 0.83 5 ? 0.7 0.0 1.8 1.1e+03 20 70 .. 463 514 .. 448 521 .. 0.86 6 ? 4.8 0.1 0.097 59 20 70 .. 503 554 .. 492 563 .. 0.87 7 ? 3.8 0.0 0.2 1.2e+02 20 70 .. 543 594 .. 532 602 .. 0.87 8 ? 3.3 0.1 0.28 1.7e+02 21 71 .. 584 635 .. 571 643 .. 0.89 9 ? 5.8 0.2 0.049 30 19 70 .. 622 674 .. 615 682 .. 0.89 10 ? 7.9 0.2 0.011 6.6 19 70 .. 662 714 .. 650 723 .. 0.88 11 ? 4.2 0.1 0.15 89 20 71 .. 743 795 .. 735 806 .. 0.85 12 ? 1.9 0.0 0.79 4.8e+02 20 69 .. 783 833 .. 774 834 .. 0.84 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.22 DUF4810 6 dYqdalyeyykeeeedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +Yq+ y+ +d k i+ +ek++e a ++g++v G y +lG y + G+ kaie+ ek FUN_002341-T1 51 GYQNLAYAFPS--LGDFRKAIKYHEKHLEIAIEAGHRVGEGnAYGNLGNAYQSLGDFRKAIEYHEK 114 68888887776..4899999********************9679*****************99775 PP == domain 2 score: 5.9 bits; conditional E-value: 0.044 DUF4810 23 ekqieklekdiekaeakgkkvp.PGlyAelGllyakeGkkekaieqfekE 71 k ie +ek +e +++ +v G y +lG+ y + G+ +kaie+ ek FUN_002341-T1 226 RKAIEYYEKCLEIVKEVSDRVGeGGAYGNLGIAYQSLGDFQKAIEYHEKH 275 67788888889888888888862589*******************98875 PP == domain 3 score: 0.5 bits; conditional E-value: 2.1 DUF4810 22 kekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 k ie +ek++e a++ +v G y lG y + + kaie++ek FUN_002341-T1 345 FRKAIEYHEKHLEIAKEVSDRVGEGsAYGSLGNAYQSLCNFRKAIEYYEK 394 57889999**************9995699*****************9986 PP == domain 4 score: 5.9 bits; conditional E-value: 0.045 DUF4810 23 ekqieklekdiekaeakgkkvp.PGlyAelGllyakeGkkekaieqfekE 71 k ie +ek +e +++ +v G y +lG+ y + G+ +kaie+ ek FUN_002341-T1 386 RKAIEYYEKCLEIVKEVSDRVGeGGTYGNLGIAYQSLGDFQKAIEYHEKH 435 67788888888888888888862589*******************98875 PP == domain 5 score: 0.7 bits; conditional E-value: 1.8 DUF4810 20 edkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d k ie +ek++e a++ +v G y lG y + G+ kaie+ ek FUN_002341-T1 463 GDFRKAIEYHEKHLEIAKEVSDRVGEGrAYGSLGNGYQSLGDFRKAIEYHEK 514 6778999999**************9996699***********9999999775 PP == domain 6 score: 4.8 bits; conditional E-value: 0.097 DUF4810 20 edkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d k ie +ek++e a++ + v G y +lG y + G+ kaie+ ek FUN_002341-T1 503 GDFRKAIEYHEKHLEIAKEVRDGVGEGsAYGHLGNAYRSLGDFRKAIEYHEK 554 567899999****************99569******************9876 PP == domain 7 score: 3.8 bits; conditional E-value: 0.2 DUF4810 20 edkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d k ie +ek++e a++ g++v G y lG y + G+ kaie+ ek FUN_002341-T1 543 GDFRKAIEYHEKHLELAKEVGHRVGEGnAYGSLGNAYWSLGDFRKAIEYHEK 594 5678899999***************996699***************999775 PP == domain 8 score: 3.3 bits; conditional E-value: 0.28 DUF4810 21 dkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfekE 71 d k ie +ek++e a++ +v G y lG y + G+ +kaie+ ek FUN_002341-T1 584 DFRKAIEYHEKHLEIAKEVSDRVGEGrAYGSLGNAYQSLGHFQKAIEYHEKD 635 567889999***************99679******************98875 PP == domain 9 score: 5.8 bits; conditional E-value: 0.049 DUF4810 19 eedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 ++ +k ie +ekd+e a++ +v G y +lG y + G+ +kaie+ ek FUN_002341-T1 622 LGHFQKAIEYHEKDLEIAKEVSDRVGEGsAYGNLGNAYQSLGDFQKAIEYHEK 674 5678999********************9569*****************99876 PP == domain 10 score: 7.9 bits; conditional E-value: 0.011 DUF4810 19 eedkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfek 70 +d +k ie +ek++e a++ +v G y +lG+ y + G+ +kaie+ ek FUN_002341-T1 662 LGDFQKAIEYHEKHLEIAKEVSDRVGEGnAYGNLGIAYQSLGDFQKAIEYHEK 714 578999*********************9679******************9886 PP == domain 11 score: 4.2 bits; conditional E-value: 0.15 DUF4810 20 edkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfekE 71 +d k ie +ek +e a + g++v G y +lG+ y + G+ +kaie+ ek FUN_002341-T1 743 GDFRKAIEYHEKRLEIAIEVGHRVGEGnAYGNLGIAYQSLGDFQKAIEYHEKH 795 567788999999999999999999999669******************98875 PP == domain 12 score: 1.9 bits; conditional E-value: 0.79 DUF4810 20 edkekqieklekdiekaeakgkkvpPG.lyAelGllyakeGkkekaieqfe 69 +d +k ie +ek++e a++ +v G y lG y + G+ kaie+ e FUN_002341-T1 783 GDFQKAIEYHEKHLELAKEVSDRVGEGsAYGCLGNAYQSLGDFRKAIEYHE 833 678899999999999999999999999558999999999999999998865 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 7.6 4.6e+03 23 36 .. 64 77 .. 62 77 .. 0.87 2 ? 0.3 0.0 1.2 7.2e+02 19 36 .. 100 117 .. 99 118 .. 0.87 3 ? -1.9 0.0 5.7 3.5e+03 23 35 .. 184 196 .. 182 197 .. 0.88 4 ? 3.1 0.0 0.16 95 16 30 .. 224 238 .. 219 244 .. 0.86 5 ? 0.2 0.0 1.2 7.6e+02 19 36 .. 260 277 .. 259 278 .. 0.87 6 ? 0.3 0.0 1.2 7.2e+02 19 36 .. 300 317 .. 299 318 .. 0.87 7 ? -1.6 0.0 4.5 2.8e+03 23 36 .. 344 357 .. 342 357 .. 0.88 8 ? 3.4 0.0 0.12 75 16 30 .. 384 398 .. 372 404 .. 0.83 9 ? 0.2 0.0 1.2 7.6e+02 19 36 .. 420 437 .. 419 438 .. 0.87 10 ? 0.3 0.0 1.2 7.2e+02 19 36 .. 460 477 .. 459 478 .. 0.87 11 ? 0.3 0.0 1.2 7.2e+02 19 36 .. 500 517 .. 499 518 .. 0.87 12 ? -1.0 0.0 3 1.8e+03 23 36 .. 544 557 .. 541 558 .. 0.88 13 ? -1.4 0.0 3.9 2.4e+03 23 36 .. 584 597 .. 582 598 .. 0.89 14 ? 0.1 0.0 1.4 8.4e+02 19 36 .. 660 677 .. 659 678 .. 0.87 15 ? 0.2 0.0 1.2 7.6e+02 19 36 .. 700 717 .. 699 718 .. 0.87 16 ? 0.2 0.0 1.2 7.6e+02 19 36 .. 780 797 .. 779 798 .. 0.87 17 ? -0.9 0.0 2.7 1.7e+03 19 35 .. 820 836 .. 819 838 .. 0.81 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 7.6 SHNi-TPR 23 DlrkaLeLreellp 36 D+rka++ e++l+ FUN_002341-T1 64 DFRKAIKYHEKHLE 77 9*****99999975 PP == domain 2 score: 0.3 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D+rka+e e++l+ FUN_002341-T1 100 QSLGDFRKAIEYHEKHLE 117 6778*******9999986 PP == domain 3 score: -1.9 bits; conditional E-value: 5.7 SHNi-TPR 23 DlrkaLeLreell 35 D+rka+e e+++ FUN_002341-T1 184 DFRKAIEYHEKHF 196 9******999997 PP == domain 4 score: 3.1 bits; conditional E-value: 0.16 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 nF A++ ++k+Le+ FUN_002341-T1 224 NFRKAIEYYEKCLEI 238 899999999999998 PP == domain 5 score: 0.2 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D++ka+e e++l+ FUN_002341-T1 260 QSLGDFQKAIEYHEKHLE 277 6778*******9999986 PP == domain 6 score: 0.3 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D+rka+e e++l+ FUN_002341-T1 300 QSLGDFRKAIEYHEKHLE 317 6778*******9999986 PP == domain 7 score: -1.6 bits; conditional E-value: 4.5 SHNi-TPR 23 DlrkaLeLreellp 36 D+rka+e e++l+ FUN_002341-T1 344 DFRKAIEYHEKHLE 357 9******9999985 PP == domain 8 score: 3.4 bits; conditional E-value: 0.12 SHNi-TPR 16 nFeqAvkDlrkaLeL 30 nF A++ ++k+Le+ FUN_002341-T1 384 NFRKAIEYYEKCLEI 398 899999999999998 PP == domain 9 score: 0.2 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D++ka+e e++l+ FUN_002341-T1 420 QSLGDFQKAIEYHEKHLE 437 6778*******9999986 PP == domain 10 score: 0.3 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D+rka+e e++l+ FUN_002341-T1 460 QSLGDFRKAIEYHEKHLE 477 6778*******9999986 PP == domain 11 score: 0.3 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D+rka+e e++l+ FUN_002341-T1 500 QSLGDFRKAIEYHEKHLE 517 6778*******9999986 PP == domain 12 score: -1.0 bits; conditional E-value: 3 SHNi-TPR 23 DlrkaLeLreellp 36 D+rka+e e++l+ FUN_002341-T1 544 DFRKAIEYHEKHLE 557 9******9999986 PP == domain 13 score: -1.4 bits; conditional E-value: 3.9 SHNi-TPR 23 DlrkaLeLreellp 36 D+rka+e e++l+ FUN_002341-T1 584 DFRKAIEYHEKHLE 597 9******9999986 PP == domain 14 score: 0.1 bits; conditional E-value: 1.4 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D++ka+e e++l+ FUN_002341-T1 660 QSLGDFQKAIEYHEKHLE 677 6778*******9999986 PP == domain 15 score: 0.2 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D++ka+e e++l+ FUN_002341-T1 700 QSLGDFQKAIEYHEKHLE 717 6778*******9999986 PP == domain 16 score: 0.2 bits; conditional E-value: 1.2 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D++ka+e e++l+ FUN_002341-T1 780 QSLGDFQKAIEYHEKHLE 797 6778*******9999986 PP == domain 17 score: -0.9 bits; conditional E-value: 2.7 SHNi-TPR 19 qAvkDlrkaLeLreell 35 q + D+rka+e e++l FUN_002341-T1 820 QSLGDFRKAIEYHEKCL 836 677899**999888876 PP >> DHR-2_Lobe_A DHR-2, Lobe A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.0 0.51 3.1e+02 109 151 .. 186 228 .. 174 230 .. 0.85 2 ? 5.1 0.0 0.062 38 101 152 .. 218 269 .. 214 271 .. 0.88 3 ? -0.6 0.0 3.4 2.1e+03 110 152 .. 307 349 .. 272 351 .. 0.85 4 ? 5.0 0.0 0.067 41 100 152 .. 377 429 .. 368 431 .. 0.88 5 ? 1.2 0.0 0.98 6e+02 110 152 .. 467 509 .. 433 511 .. 0.88 6 ? 2.3 0.0 0.46 2.8e+02 112 152 .. 589 629 .. 581 631 .. 0.88 7 ? -1.0 0.0 4.7 2.9e+03 112 152 .. 629 669 .. 624 671 .. 0.87 8 ? -0.6 0.0 3.4 2.1e+03 105 152 .. 662 709 .. 649 711 .. 0.79 9 ? -1.8 0.0 8.1 4.9e+03 108 151 .. 705 748 .. 698 750 .. 0.78 10 ? -1.4 0.0 6.1 3.7e+03 108 152 .. 785 829 .. 777 830 .. 0.79 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.51 DHR-2_Lobe_A 109 lkkaelyElaielyklllpiyekkrdYkklseihkklaelyek 151 k e++E +++ k+++ + r+Y +l ++++ l ++ + FUN_002341-T1 186 RKAIEYHEKHFKIAKEVSDRVGEGRAYGNLGNAYQSLCNFRKA 228 456699*****************************99887665 PP == domain 2 score: 5.1 bits; conditional E-value: 0.062 DHR-2_Lobe_A 101 lleeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 +++ +++ k e+yE + e+ k+++ + +Y +l +++ l ++ + i FUN_002341-T1 218 AYQSLCNFRKAIEYYEKCLEIVKEVSDRVGEGGAYGNLGIAYQSLGDFQKAI 269 577888999999**************************99999999887766 PP == domain 3 score: -0.6 bits; conditional E-value: 3.4 DHR-2_Lobe_A 110 kkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 k e++E e+ k+++ + r+Y +l + ++ l ++ + i FUN_002341-T1 307 KAIEYHEKHLEIAKEVSDRVGEGRAYGSLGDDYQLLGDFRKAI 349 5568999999999999999999999999999999888876665 PP == domain 4 score: 5.0 bits; conditional E-value: 0.067 DHR-2_Lobe_A 100 elleeaidylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + +++ +++ k e+yE + e+ k+++ + Y +l +++ l ++ + i FUN_002341-T1 377 NAYQSLCNFRKAIEYYEKCLEIVKEVSDRVGEGGTYGNLGIAYQSLGDFQKAI 429 5678889999999*****************99999999999999998887766 PP == domain 5 score: 1.2 bits; conditional E-value: 0.98 DHR-2_Lobe_A 110 kkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 k e++E e+ k+++ + r+Y +l + ++ l ++ + i FUN_002341-T1 467 KAIEYHEKHLEIAKEVSDRVGEGRAYGSLGNGYQSLGDFRKAI 509 55699*****************************999987766 PP == domain 6 score: 2.3 bits; conditional E-value: 0.46 DHR-2_Lobe_A 112 aelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e++E e+ k+++ + r+Y +l ++++ l + + i FUN_002341-T1 589 IEYHEKHLEIAKEVSDRVGEGRAYGSLGNAYQSLGHFQKAI 629 5899****************************998877665 PP == domain 7 score: -1.0 bits; conditional E-value: 4.7 DHR-2_Lobe_A 112 aelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e++E e+ k+++ + +Y +l ++++ l ++ + i FUN_002341-T1 629 IEYHEKDLEIAKEVSDRVGEGSAYGNLGNAYQSLGDFQKAI 669 4899999999***********************99988776 PP == domain 8 score: -0.6 bits; conditional E-value: 3.4 DHR-2_Lobe_A 105 aidylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 d+ k e++E e+ k+++ + ++Y +l +++ l ++ + i FUN_002341-T1 662 LGDFQKAIEYHEKHLEIAKEVSDRVGEGNAYGNLGIAYQSLGDFQKAI 709 556667778999999999999999999999999999998888877665 PP == domain 9 score: -1.8 bits; conditional E-value: 8.1 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyek 151 + k e++E el k+++ + +Y l ++++ l ++ + FUN_002341-T1 705 FQKAIEYHEKHLELAKEVSHRVGEGSAYGCLGSAYQSLGDFRKA 748 45566889999999999999999999999999999988887665 PP == domain 10 score: -1.4 bits; conditional E-value: 6.1 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + k e++E el k+++ + +Y l ++++ l ++ + i FUN_002341-T1 785 FQKAIEYHEKHLELAKEVSDRVGEGSAYGCLGNAYQSLGDFRKAI 829 555668999999999999999999999999999999988876655 PP >> DUF7018 Domain of unknown function (DUF7018) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.1 2.9 1.8e+03 72 89 .. 105 122 .. 97 173 .. 0.58 2 ? 2.3 0.1 0.43 2.6e+02 71 92 .. 184 205 .. 177 211 .. 0.87 3 ? 3.9 0.0 0.14 82 71 91 .. 224 244 .. 217 250 .. 0.85 4 ? 2.6 0.0 0.35 2.1e+02 71 92 .. 264 285 .. 258 294 .. 0.87 5 ? 2.0 0.0 0.56 3.4e+02 70 92 .. 303 325 .. 292 332 .. 0.84 6 ? 1.8 0.0 0.61 3.7e+02 70 92 .. 343 365 .. 330 378 .. 0.87 7 ? 4.0 0.0 0.13 81 71 92 .. 384 405 .. 377 411 .. 0.86 8 ? 2.7 0.0 0.33 2e+02 71 92 .. 424 445 .. 418 458 .. 0.87 9 ? 1.9 0.0 0.57 3.5e+02 70 92 .. 463 485 .. 456 494 .. 0.84 10 ? 0.5 0.0 1.6 9.9e+02 71 89 .. 504 522 .. 497 529 .. 0.88 11 ? 1.4 0.0 0.85 5.2e+02 71 90 .. 544 563 .. 537 572 .. 0.87 12 ? 2.5 0.2 0.37 2.3e+02 72 92 .. 585 605 .. 581 657 .. 0.52 13 ? 1.9 0.1 0.56 3.4e+02 71 92 .. 664 685 .. 657 691 .. 0.85 14 ? 2.7 0.1 0.33 2e+02 71 92 .. 704 725 .. 698 742 .. 0.87 15 ? -1.9 0.0 8.5 5.2e+03 71 88 .. 744 761 .. 736 766 .. 0.82 16 ? 2.7 0.0 0.32 1.9e+02 71 92 .. 784 805 .. 778 822 .. 0.87 17 ? -1.8 0.0 8 4.9e+03 71 88 .. 824 841 .. 815 851 .. 0.78 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 2.9 DUF7018 72 lekaidhyekslklieea 89 + kai+++ek l+++ e+ FUN_002341-T1 105 FRKAIEYHEKHLEIAIEV 122 666666666666655444 PP == domain 2 score: 2.3 bits; conditional E-value: 0.43 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai+++ek +k+++e+ ++ FUN_002341-T1 184 DFRKAIEYHEKHFKIAKEVSDR 205 899**************98665 PP == domain 3 score: 3.9 bits; conditional E-value: 0.14 DUF7018 71 llekaidhyekslklieeave 91 ++ kai++yek l++++e+ + FUN_002341-T1 224 NFRKAIEYYEKCLEIVKEVSD 244 689**************9866 PP == domain 4 score: 2.6 bits; conditional E-value: 0.35 DUF7018 71 llekaidhyekslklieeavek 92 +++kai+++ek l+l++e+ ++ FUN_002341-T1 264 DFQKAIEYHEKHLELAKEVSDR 285 89***************98765 PP == domain 5 score: 2.0 bits; conditional E-value: 0.56 DUF7018 70 kllekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002341-T1 303 GDFRKAIEYHEKHLEIAKEVSDR 325 489**************998665 PP == domain 6 score: 1.8 bits; conditional E-value: 0.61 DUF7018 70 kllekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002341-T1 343 GDFRKAIEYHEKHLEIAKEVSDR 365 589***************98765 PP == domain 7 score: 4.0 bits; conditional E-value: 0.13 DUF7018 71 llekaidhyekslklieeavek 92 ++ kai++yek l++++e+ ++ FUN_002341-T1 384 NFRKAIEYYEKCLEIVKEVSDR 405 689**************98665 PP == domain 8 score: 2.7 bits; conditional E-value: 0.33 DUF7018 71 llekaidhyekslklieeavek 92 +++kai+++ek l+l++e+ ++ FUN_002341-T1 424 DFQKAIEYHEKHLELAKEVSDR 445 89***************98765 PP == domain 9 score: 1.9 bits; conditional E-value: 0.57 DUF7018 70 kllekaidhyekslklieeavek 92 ++ kai+++ek l++++e+ ++ FUN_002341-T1 463 GDFRKAIEYHEKHLEIAKEVSDR 485 489**************998765 PP == domain 10 score: 0.5 bits; conditional E-value: 1.6 DUF7018 71 llekaidhyekslklieea 89 ++ kai+++ek l++++e+ FUN_002341-T1 504 DFRKAIEYHEKHLEIAKEV 522 899************9986 PP == domain 11 score: 1.4 bits; conditional E-value: 0.85 DUF7018 71 llekaidhyekslklieeav 90 ++ kai+++ek l+l++e+ FUN_002341-T1 544 DFRKAIEYHEKHLELAKEVG 563 899*************9975 PP == domain 12 score: 2.5 bits; conditional E-value: 0.37 DUF7018 72 lekaidhyekslklieeavek 92 + kai+++ek l++++e+ ++ FUN_002341-T1 585 FRKAIEYHEKHLEIAKEVSDR 605 566666666666666665544 PP == domain 13 score: 1.9 bits; conditional E-value: 0.56 DUF7018 71 llekaidhyekslklieeavek 92 +++kai+++ek l++++e+ ++ FUN_002341-T1 664 DFQKAIEYHEKHLEIAKEVSDR 685 89**************998665 PP == domain 14 score: 2.7 bits; conditional E-value: 0.33 DUF7018 71 llekaidhyekslklieeavek 92 +++kai+++ek l+l++e+ ++ FUN_002341-T1 704 DFQKAIEYHEKHLELAKEVSHR 725 89***************98766 PP == domain 15 score: -1.9 bits; conditional E-value: 8.5 DUF7018 71 llekaidhyekslkliee 88 ++ kai+++ek l+++ e FUN_002341-T1 744 DFRKAIEYHEKRLEIAIE 761 899*******99998765 PP == domain 16 score: 2.7 bits; conditional E-value: 0.32 DUF7018 71 llekaidhyekslklieeavek 92 +++kai+++ek l+l++e+ ++ FUN_002341-T1 784 DFQKAIEYHEKHLELAKEVSDR 805 89***************98766 PP == domain 17 score: -1.8 bits; conditional E-value: 8 DUF7018 71 llekaidhyekslkliee 88 ++ kai+++ek lk+ e FUN_002341-T1 824 DFRKAIEYHEKCLKIDIE 841 799999999999987555 PP >> TPR_BSK1_C Serine/threonine-protein kinase BSK1-like, TPR repeats # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.0 8.6 5.2e+03 57 79 .. 184 206 .. 181 218 .. 0.84 2 ? 2.3 0.0 0.34 2.1e+02 57 79 .. 224 246 .. 210 283 .. 0.83 3 ? -0.6 0.0 2.7 1.6e+03 57 80 .. 304 327 .. 299 353 .. 0.84 4 ? -1.3 0.0 4.5 2.7e+03 57 77 .. 344 364 .. 334 367 .. 0.84 5 ? 1.9 0.0 0.47 2.9e+02 57 78 .. 384 405 .. 376 429 .. 0.89 6 ? -1.6 0.0 5.3 3.3e+03 57 77 .. 424 444 .. 416 448 .. 0.84 7 ? 0.1 0.0 1.7 1e+03 57 84 .. 464 491 .. 459 520 .. 0.75 8 ? 0.3 0.0 1.4 8.4e+02 56 83 .. 583 610 .. 574 646 .. 0.79 9 ? -0.6 0.0 2.8 1.7e+03 57 78 .. 664 685 .. 654 710 .. 0.84 10 ? -0.5 0.0 2.6 1.6e+03 57 79 .. 704 726 .. 696 759 .. 0.76 11 ? -0.5 0.0 2.6 1.6e+03 57 79 .. 784 806 .. 777 838 .. 0.70 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 8.6 TPR_BSK1_C 57 dfktaiecytqfidagtmvsptv 79 df++aie+ + ++ + vs v FUN_002341-T1 184 DFRKAIEYHEKHFKIAKEVSDRV 206 9*******999999988888766 PP == domain 2 score: 2.3 bits; conditional E-value: 0.34 TPR_BSK1_C 57 dfktaiecytqfidagtmvsptv 79 +f++aie+y ++++ + vs v FUN_002341-T1 224 NFRKAIEYYEKCLEIVKEVSDRV 246 799*********99999888665 PP == domain 3 score: -0.6 bits; conditional E-value: 2.7 TPR_BSK1_C 57 dfktaiecytqfidagtmvsptvy 80 df++aie+ + ++ + vs v FUN_002341-T1 304 DFRKAIEYHEKHLEIAKEVSDRVG 327 9**********9999999988775 PP == domain 4 score: -1.3 bits; conditional E-value: 4.5 TPR_BSK1_C 57 dfktaiecytqfidagtmvsp 77 df++aie+ + ++ + vs FUN_002341-T1 344 DFRKAIEYHEKHLEIAKEVSD 364 9**********9999988876 PP == domain 5 score: 1.9 bits; conditional E-value: 0.47 TPR_BSK1_C 57 dfktaiecytqfidagtmvspt 78 +f++aie+y ++++ + vs FUN_002341-T1 384 NFRKAIEYYEKCLEIVKEVSDR 405 79************99988865 PP == domain 6 score: -1.6 bits; conditional E-value: 5.3 TPR_BSK1_C 57 dfktaiecytqfidagtmvsp 77 df++aie+ + ++ + vs FUN_002341-T1 424 DFQKAIEYHEKHLELAKEVSD 444 9*********99999888876 PP == domain 7 score: 0.1 bits; conditional E-value: 1.7 TPR_BSK1_C 57 dfktaiecytqfidagtmvsptvyarrs 84 df++aie+ + ++ + vs v r+ FUN_002341-T1 464 DFRKAIEYHEKHLEIAKEVSDRVGEGRA 491 8999999999999999999888766665 PP == domain 8 score: 0.3 bits; conditional E-value: 1.4 TPR_BSK1_C 56 kdfktaiecytqfidagtmvsptvyarr 83 df++aie+ + ++ + vs v r FUN_002341-T1 583 GDFRKAIEYHEKHLEIAKEVSDRVGEGR 610 599*******999999999998776555 PP == domain 9 score: -0.6 bits; conditional E-value: 2.8 TPR_BSK1_C 57 dfktaiecytqfidagtmvspt 78 df++aie+ + ++ + vs FUN_002341-T1 664 DFQKAIEYHEKHLEIAKEVSDR 685 9**********99999988865 PP == domain 10 score: -0.5 bits; conditional E-value: 2.6 TPR_BSK1_C 57 dfktaiecytqfidagtmvsptv 79 df++aie+ + ++ + vs v FUN_002341-T1 704 DFQKAIEYHEKHLELAKEVSHRV 726 89999999999999888888765 PP == domain 11 score: -0.5 bits; conditional E-value: 2.6 TPR_BSK1_C 57 dfktaiecytqfidagtmvsptv 79 df++aie+ + ++ + vs v FUN_002341-T1 784 DFQKAIEYHEKHLELAKEVSDRV 806 89999999999988888887765 PP >> TRAPPC9-Trs120 Trs120/TRAPPC9, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 2 1.2e+03 273 312 .. 175 214 .. 168 258 .. 0.74 2 ? 3.2 0.0 0.09 54 257 313 .. 319 375 .. 270 380 .. 0.85 3 ? 1.5 0.0 0.3 1.8e+02 257 313 .. 479 535 .. 431 539 .. 0.84 4 ? 3.9 0.0 0.058 35 261 313 .. 603 655 .. 585 663 .. 0.87 5 ? -1.3 0.0 2.1 1.3e+03 273 301 .. 855 883 .. 847 886 .. 0.83 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 2 TRAPPC9-Trs120 273 lGnlyLlAGrysdAlkefteaatlakklsDylWlgkALEg 312 lGn y l G + A++ ++ak++sD + g+A + FUN_002341-T1 175 LGNAYQLLGDFRKAIEYHEKHFKIAKEVSDRVGEGRAYGN 214 6777777777777777777777788887777766666544 PP == domain 2 score: 3.2 bits; conditional E-value: 0.09 TRAPPC9-Trs120 257 asersrqrgkGRqskvlGnlyLlAGrysdAlkefteaatlakklsDylWlgkALEgi 313 a+e s g+GR+ lG+ y l G + A++ +++ak++sD + g+A ++ FUN_002341-T1 319 AKEVSDRVGEGRAYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEVSDRVGEGSAYGSL 375 5556666689**************************************999997665 PP == domain 3 score: 1.5 bits; conditional E-value: 0.3 TRAPPC9-Trs120 257 asersrqrgkGRqskvlGnlyLlAGrysdAlkefteaatlakklsDylWlgkALEgi 313 a+e s g+GR+ lGn y G + A++ +++ak+++D + g+A ++ FUN_002341-T1 479 AKEVSDRVGEGRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEVRDGVGEGSAYGHL 535 5555666689************************************99999997665 PP == domain 4 score: 3.9 bits; conditional E-value: 0.058 TRAPPC9-Trs120 261 srqrgkGRqskvlGnlyLlAGrysdAlkefteaatlakklsDylWlgkALEgi 313 s g+GR+ lGn y G ++ A++ +++ak++sD + g+A ++ FUN_002341-T1 603 SDRVGEGRAYGSLGNAYQSLGHFQKAIEYHEKDLEIAKEVSDRVGEGSAYGNL 655 555679**************************************999997666 PP == domain 5 score: -1.3 bits; conditional E-value: 2.1 TRAPPC9-Trs120 273 lGnlyLlAGrysdAlkefteaatlakkls 301 +G+ y G++ +Al +f+ a+++ +l+ FUN_002341-T1 855 IGQGYFSLGQFENALDKFISAVKVFNTLR 883 78899999*************99877665 PP >> NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 6.4 3.9e+03 67 89 .. 67 87 .. 52 101 .. 0.83 2 ? -1.5 0.0 6.4 3.9e+03 67 89 .. 107 127 .. 86 142 .. 0.84 3 ? 4.3 0.0 0.1 63 70 89 .. 148 167 .. 139 200 .. 0.85 4 ? -1.9 0.0 8.6 5.2e+03 70 102 .. 548 580 .. 520 608 .. 0.70 5 ? 2.5 0.0 0.39 2.4e+02 70 89 .. 628 647 .. 613 687 .. 0.83 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 6.4 NAD_binding_11 67 pgFaidlllKDlglaldlarelg 89 + ai+++ K l++a+++++++g FUN_002341-T1 67 K--AIKYHEKHLEIAIEAGHRVG 87 4..799*************9987 PP == domain 2 score: -1.5 bits; conditional E-value: 6.4 NAD_binding_11 67 pgFaidlllKDlglaldlarelg 89 + ai+++ K l++a+++++++g FUN_002341-T1 107 K--AIEYHEKHLEIAIEVGHRVG 127 3..799************99987 PP == domain 3 score: 4.3 bits; conditional E-value: 0.1 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ KDl++a+++++++g FUN_002341-T1 148 AIKYHEKDLEIAIEVGHRVG 167 799*************9987 PP == domain 4 score: -1.9 bits; conditional E-value: 8.6 NAD_binding_11 70 aidlllKDlglaldlarelgvplpltalaeqly 102 ai+++ K l+la ++++++g ++l ++ + FUN_002341-T1 548 AIEYHEKHLELAKEVGHRVGEGNAYGSLGNAYW 580 688888888888888888775555555554444 PP == domain 5 score: 2.5 bits; conditional E-value: 0.39 NAD_binding_11 70 aidlllKDlglaldlarelg 89 ai+++ KDl++a ++ +++g FUN_002341-T1 628 AIEYHEKDLEIAKEVSDRVG 647 799***********999887 PP >> DDT DDT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.0 0.0 2.3 1.4e+03 25 39 .. 260 274 .. 254 282 .. 0.73 2 ? -0.0 0.0 2.3 1.4e+03 25 39 .. 420 434 .. 414 442 .. 0.73 3 ? -1.8 0.0 8.1 4.9e+03 26 39 .. 661 674 .. 660 681 .. 0.83 4 ? 0.2 0.0 1.9 1.1e+03 22 39 .. 697 714 .. 692 724 .. 0.74 5 ? 0.1 0.0 2.1 1.3e+03 22 39 .. 777 794 .. 772 802 .. 0.74 6 ? -1.9 0.1 8.6 5.2e+03 25 34 .. 860 869 .. 858 879 .. 0.88 Alignments for each domain: == domain 1 score: -0.0 bits; conditional E-value: 2.3 DDT 25 ftlddFeeALlcsee 39 +l dF++A+ ++e+ FUN_002341-T1 260 QSLGDFQKAIEYHEK 274 5899******99997 PP == domain 2 score: -0.0 bits; conditional E-value: 2.3 DDT 25 ftlddFeeALlcsee 39 +l dF++A+ ++e+ FUN_002341-T1 420 QSLGDFQKAIEYHEK 434 5899******99997 PP == domain 3 score: -1.8 bits; conditional E-value: 8.1 DDT 26 tlddFeeALlcsee 39 +l dF++A+ ++e+ FUN_002341-T1 661 SLGDFQKAIEYHEK 674 689******99886 PP == domain 4 score: 0.2 bits; conditional E-value: 1.9 DDT 22 LspftlddFeeALlcsee 39 + +l dF++A+ ++e+ FUN_002341-T1 697 IAYQSLGDFQKAIEYHEK 714 555589********9997 PP == domain 5 score: 0.1 bits; conditional E-value: 2.1 DDT 22 LspftlddFeeALlcsee 39 + +l dF++A+ ++e+ FUN_002341-T1 777 IAYQSLGDFQKAIEYHEK 794 555589*******99997 PP == domain 6 score: -1.9 bits; conditional E-value: 8.6 DDT 25 ftlddFeeAL 34 f+l +Fe+AL FUN_002341-T1 860 FSLGQFENAL 869 9999999999 PP >> FliJ Flagellar FliJ protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.0 1.4 8.3e+02 25 74 .. 232 282 .. 209 292 .. 0.66 2 ? 1.1 0.0 1 6.2e+02 16 73 .. 271 321 .. 250 332 .. 0.61 3 ? -1.7 0.0 7.4 4.5e+03 27 74 .. 314 362 .. 300 369 .. 0.70 4 ? -1.6 0.0 6.9 4.2e+03 26 71 .. 353 399 .. 340 408 .. 0.70 5 ? 0.6 0.0 1.4 8.6e+02 26 74 .. 393 442 .. 370 449 .. 0.67 6 ? 0.9 0.0 1.2 7.2e+02 16 73 .. 431 481 .. 412 490 .. 0.60 7 ? 1.3 0.0 0.87 5.3e+02 26 74 .. 513 562 .. 500 568 .. 0.80 8 ? 2.2 0.0 0.46 2.8e+02 26 74 .. 593 642 .. 585 648 .. 0.86 9 ? 2.9 0.1 0.28 1.7e+02 3 67 .. 658 722 .. 651 728 .. 0.67 10 ? -0.5 0.0 3.1 1.9e+03 41 66 .. 776 801 .. 737 832 .. 0.65 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 1.4 FliJ 25 eeyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaekq 74 +e++ e ++ s+++ +G + +l + + ++ ++aie +++ le a+++ FUN_002341-T1 232 YEKCLEIVKEVSDRVgEGGAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 282 445556666666666567777777777777777777777777777777765 PP == domain 2 score: 1.1 bits; conditional E-value: 1 FliJ 16 qaeekleeleeyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaek 73 e++ e++++ s+++ +G + l n + ++ ++aie +++ le a++ FUN_002341-T1 271 Y--------HEKHLELAKEVSDRVgEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKE 321 2........34445555666666655666666666666677777777777777776665 PP == domain 3 score: -1.7 bits; conditional E-value: 7.4 FliJ 27 yreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaekq 74 ++ e +++ s+++ +G + l + ++ ++aie +++ le a+++ FUN_002341-T1 314 KHLEIAKEVSDRVgEGRAYGSLGDDYQLLGDFRKAIEYHEKHLEIAKEV 362 4555666666666556666667777777788888888888888877765 PP == domain 4 score: -1.6 bits; conditional E-value: 6.9 FliJ 26 eyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqa 71 e++ e +++ s+++ +G + l n + + + ++aie +++ le FUN_002341-T1 353 EKHLEIAKEVSDRVgEGSAYGSLGNAYQSLCNFRKAIEYYEKCLEIV 399 45566677777777667777788888888888888888777766655 PP == domain 5 score: 0.6 bits; conditional E-value: 1.4 FliJ 26 eyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaekq 74 e++ e ++ s+++ +G + +l + + ++ ++aie +++ le a+++ FUN_002341-T1 393 EKCLEIVKEVSDRVgEGGTYGNLGIAYQSLGDFQKAIEYHEKHLELAKEV 442 45556666666666557777777777777777777777777777777765 PP == domain 6 score: 0.9 bits; conditional E-value: 1.2 FliJ 16 qaeekleeleeyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaek 73 e++ e++++ s+++ +G + l n + ++ ++aie +++ le a++ FUN_002341-T1 431 Y--------HEKHLELAKEVSDRVgEGSTYGSLGNDYQSLGDFRKAIEYHEKHLEIAKE 481 3........34445555555666645666666666666667777777777777766665 PP == domain 7 score: 1.3 bits; conditional E-value: 0.87 FliJ 26 eyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaekq 74 e++ e +++ ++ + +G + +l n + ++ ++aie +++ le a+++ FUN_002341-T1 513 EKHLEIAKEVRDGVgEGSAYGHLGNAYRSLGDFRKAIEYHEKHLELAKEV 562 455666677777776789999999999999999999*9999999999986 PP == domain 8 score: 2.2 bits; conditional E-value: 0.46 FliJ 26 eyreeyqqqlsgal.qGlsaaelrnyqafisqldeaieqqqqeleqaekq 74 e++ e +++ s+++ +G + l n + +++ ++aie ++++le a+++ FUN_002341-T1 593 EKHLEIAKEVSDRVgEGRAYGSLGNAYQSLGHFQKAIEYHEKDLEIAKEV 642 5677888999999977999999**********************999876 PP == domain 9 score: 2.9 bits; conditional E-value: 0.28 FliJ 3 aarelaeaqqeleqaeekleeleeyreeyqqqlsgalq.Glsaaelrnyqafisqldeaieqqqqe 67 a + l+ q+++e +e++le +e ++ + + ++ G++ + l +q+ i++ ++++e +++ FUN_002341-T1 658 AYQSLGDFQKAIEYHEKHLEIAKEVSDRVGEG-NAYGNlGIAYQSLGDFQKAIEYHEKHLELAKEV 722 55677777777777777776666555555333.333333888888888888888888887777765 PP == domain 10 score: -0.5 bits; conditional E-value: 3.1 FliJ 41 Glsaaelrnyqafisqldeaieqqqq 66 G++ + l +q+ i++ ++++e +++ FUN_002341-T1 776 GIAYQSLGDFQKAIEYHEKHLELAKE 801 55555555555555555555555544 PP >> ARM_TT21_C Tetratricopeptide repeat protein 21 C-terminal ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 8.3 5e+03 130 163 .. 90 123 .. 72 135 .. 0.80 2 ? 2.4 0.1 0.28 1.7e+02 130 167 .. 170 207 .. 149 215 .. 0.86 3 ? 5.1 0.1 0.042 26 129 167 .. 209 247 .. 207 256 .. 0.90 4 ? -0.1 0.0 1.7 1e+03 131 167 .. 251 287 .. 248 292 .. 0.92 5 ? 4.5 0.1 0.064 39 129 167 .. 369 407 .. 347 409 .. 0.81 6 ? -1.0 0.1 3.1 1.9e+03 131 167 .. 411 447 .. 387 448 .. 0.77 7 ? 0.9 0.1 0.82 5e+02 129 171 .. 489 531 .. 463 538 .. 0.78 8 ? -1.3 0.0 3.8 2.3e+03 130 167 .. 530 567 .. 528 577 .. 0.86 9 ? -1.2 0.1 3.5 2.1e+03 112 167 .. 557 607 .. 545 608 .. 0.76 10 ? 4.4 0.4 0.071 43 114 168 .. 599 648 .. 569 659 .. 0.77 11 ? 3.8 0.3 0.11 66 108 167 .. 673 727 .. 655 738 .. 0.80 12 ? 2.7 0.2 0.22 1.4e+02 119 167 .. 764 807 .. 745 842 .. 0.78 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 8.3 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklskess 163 Ay lG +++ +++A+e+ ek +++ e FUN_002341-T1 90 NAYGNLGNAYQSLGDFRKAIEYHEKHLEIAIEVG 123 6899999999999999999999998777665544 PP == domain 2 score: 2.4 bits; conditional E-value: 0.28 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklskesspavG 167 Ay lG ++ +++A+e+ ek +k++ke s +vG FUN_002341-T1 170 DAYGSLGNAYQLLGDFRKAIEYHEKHFKIAKEVSDRVG 207 599999**************************999998 PP == domain 3 score: 5.1 bits; conditional E-value: 0.042 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskesspavG 167 ++Ay lG +++ ++++A+e+Yek ++ ke s +vG FUN_002341-T1 209 GRAYGNLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDRVG 247 589***************************999999998 PP == domain 4 score: -0.1 bits; conditional E-value: 1.7 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklskesspavG 167 Ay lG+ +++ +++A+e+ ek +l+ke s +vG FUN_002341-T1 251 AYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVG 287 89999********************999999988887 PP == domain 5 score: 4.5 bits; conditional E-value: 0.064 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskesspavG 167 + Ay lG +++ ++++A+e+Yek ++ ke s +vG FUN_002341-T1 369 GSAYGSLGNAYQSLCNFRKAIEYYEKCLEIVKEVSDRVG 407 569*************************99999888887 PP == domain 6 score: -1.0 bits; conditional E-value: 3.1 ARM_TT21_C 131 AyellGliaekeqsykdAaenYekAWklskesspavG 167 y lG+ +++ +++A+e+ ek +l+ke s +vG FUN_002341-T1 411 TYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVG 447 5778999999999**********99999999888887 PP == domain 7 score: 0.9 bits; conditional E-value: 0.82 ARM_TT21_C 129 akAyellGliaekeqsykdAaenYekAWklskesspavGykLA 171 ++Ay lG +++ +++A+e+ ek +++ke + vG A FUN_002341-T1 489 GRAYGSLGNGYQSLGDFRKAIEYHEKHLEIAKEVRDGVGEGSA 531 79************************99999999888885555 PP == domain 8 score: -1.3 bits; conditional E-value: 3.8 ARM_TT21_C 130 kAyellGliaekeqsykdAaenYekAWklskesspavG 167 Ay lG + + +++A+e+ ek +l+ke +vG FUN_002341-T1 530 SAYGHLGNAYRSLGDFRKAIEYHEKHLELAKEVGHRVG 567 589999999****************9999998877777 PP == domain 9 score: -1.2 bits; conditional E-value: 3.5 ARM_TT21_C 112 dlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavG 167 +lA+e+ ++v + + Ay lG + + +++A+e+ ek +++ke s +vG FUN_002341-T1 557 ELAKEVGHRVGE-----GNAYGSLGNAYWSLGDFRKAIEYHEKHLEIAKEVSDRVG 607 555555555544.....458999999999999999999999999999998888777 PP == domain 10 score: 4.4 bits; conditional E-value: 0.071 ARM_TT21_C 114 AeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavGy 168 A+e+ ++v ++Ay lG +++ ++++A+e+ ek +++ke s +vG FUN_002341-T1 599 AKEVSDRVG-----EGRAYGSLGNAYQSLGHFQKAIEYHEKDLEIAKEVSDRVGE 648 444444443.....369****************************9999999985 PP == domain 11 score: 3.8 bits; conditional E-value: 0.11 ARM_TT21_C 108 sgkldlAeeLlkkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavG 167 +++l++A+e+ ++v + Ay lG+ +++ +++A+e+ ek +l+ke s +vG FUN_002341-T1 673 EKHLEIAKEVSDRVGEG-----NAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSHRVG 727 45556666666666554.....59*****************************9999998 PP == domain 12 score: 2.7 bits; conditional E-value: 0.22 ARM_TT21_C 119 kkvlkynkscakAyellGliaekeqsykdAaenYekAWklskesspavG 167 ++v + + Ay lG+ +++ +++A+e+ ek +l+ke s +vG FUN_002341-T1 764 HRVGE-----GNAYGNLGIAYQSLGDFQKAIEYHEKHLELAKEVSDRVG 807 55544.....359999999999999999999999999999999998888 PP >> PT26-6P_helical PT26-6P, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 6.7 4.1e+03 61 106 .. 22 65 .. 20 76 .. 0.78 2 ? -1.5 0.0 6.4 3.9e+03 65 107 .. 66 106 .. 62 116 .. 0.86 3 ? 4.7 0.1 0.078 47 65 107 .. 226 266 .. 213 276 .. 0.83 4 ? -0.1 0.0 2.3 1.4e+03 65 107 .. 306 346 .. 295 354 .. 0.85 5 ? 4.5 0.0 0.091 55 65 106 .. 386 425 .. 376 430 .. 0.84 6 ? -0.8 0.0 3.9 2.4e+03 65 107 .. 426 466 .. 424 474 .. 0.84 7 ? -1.0 0.0 4.2 2.6e+03 65 106 .. 466 505 .. 453 511 .. 0.81 8 ? 1.3 0.2 0.86 5.2e+02 64 107 .. 625 666 .. 589 671 .. 0.84 9 ? 0.3 0.3 1.8 1.1e+03 65 107 .. 666 706 .. 629 717 .. 0.80 10 ? -1.7 0.0 7.1 4.3e+03 65 106 .. 786 825 .. 748 832 .. 0.71 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 6.7 PT26-6P_helical 61 kllaekaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 k + +kaie++++ + +e d + e + + ++a + Gdf FUN_002341-T1 22 KGYFRKAIEYHEKHLKVT--MELGDCAGEEKGYQNLAYAFPSLGDF 65 668899999999988754..55667788888888888888888888 PP == domain 2 score: -1.5 bits; conditional E-value: 6.4 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdfy 107 +kai+++++ +e ie + v e + ++ ++ Gdf FUN_002341-T1 66 RKAIKYHEKHLEI--AIEAGHRVGEGNAYGNLGNAYQSLGDFR 106 6999999999996..6999999999999999999999999995 PP == domain 3 score: 4.7 bits; conditional E-value: 0.078 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdfy 107 +kaie+y++++e ++++ +d v e + ++ ++ Gdf FUN_002341-T1 226 RKAIEYYEKCLEIVKEV--SDRVGEGGAYGNLGIAYQSLGDFQ 266 7************9977..688888888888888999999985 PP == domain 4 score: -0.1 bits; conditional E-value: 2.3 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdfy 107 +kaie++++ +e +++ +d v e + + + +++ Gdf FUN_002341-T1 306 RKAIEYHEKHLEIAKEV--SDRVGEGRAYGSLGDDYQLLGDFR 346 79*********998865..789999999999999999999995 PP == domain 5 score: 4.5 bits; conditional E-value: 0.091 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 +kaie+y++++e ++++ +d v e + ++ ++ Gdf FUN_002341-T1 386 RKAIEYYEKCLEIVKEV--SDRVGEGGTYGNLGIAYQSLGDF 425 79***********9977..68888888888888889999998 PP == domain 6 score: -0.8 bits; conditional E-value: 3.9 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdfy 107 +kaie++++ +e +++ +d v e + + +++ Gdf FUN_002341-T1 426 QKAIEYHEKHLELAKEV--SDRVGEGSTYGSLGNDYQSLGDFR 466 69999999999987765..788999999999999999999985 PP == domain 7 score: -1.0 bits; conditional E-value: 4.2 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 +kaie++++ +e +++ +d v e + + + ++ Gdf FUN_002341-T1 466 RKAIEYHEKHLEIAKEV--SDRVGEGRAYGSLGNGYQSLGDF 505 79*******99998865..78888888888888888888888 PP == domain 8 score: 1.3 bits; conditional E-value: 0.86 PT26-6P_helical 64 aekaieayddaiealrkieqtdavdeillalkvakkleqiGdfy 107 +kaie++++ +e +++ +d v e + ++ ++ Gdf FUN_002341-T1 625 FQKAIEYHEKDLEIAKEV--SDRVGEGSAYGNLGNAYQSLGDFQ 666 479999999999988765..789999999999999999999995 PP == domain 9 score: 0.3 bits; conditional E-value: 1.8 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdfy 107 +kaie++++ +e +++ +d v e + ++ ++ Gdf FUN_002341-T1 666 QKAIEYHEKHLEIAKEV--SDRVGEGNAYGNLGIAYQSLGDFQ 706 68888888888887755..678888888888888888888885 PP == domain 10 score: -1.7 bits; conditional E-value: 7.1 PT26-6P_helical 65 ekaieayddaiealrkieqtdavdeillalkvakkleqiGdf 106 +kaie++++ +e +++ +d v e + + ++ Gdf FUN_002341-T1 786 QKAIEYHEKHLELAKEV--SDRVGEGSAYGCLGNAYQSLGDF 825 57777777777765544..55666666666666666666666 PP >> Mre11_C_bact Mre11 C-terminal domain, bacteria # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.2 0.0 0.012 7 18 40 .. 22 44 .. 19 47 .. 0.91 2 ? -1.9 0.1 8 4.9e+03 23 35 .. 107 119 .. 105 126 .. 0.79 3 ? 3.6 0.0 0.16 95 22 42 .. 186 206 .. 180 211 .. 0.86 4 ? 0.3 0.0 1.6 9.7e+02 23 42 .. 227 246 .. 224 251 .. 0.84 5 ? -0.6 0.1 3.1 1.9e+03 23 42 .. 267 286 .. 265 289 .. 0.83 6 ? 2.6 0.0 0.32 1.9e+02 22 42 .. 306 326 .. 302 331 .. 0.86 7 ? 3.0 0.1 0.24 1.5e+02 22 42 .. 346 366 .. 337 371 .. 0.83 8 ? 0.0 0.0 2 1.2e+03 23 42 .. 387 406 .. 384 409 .. 0.85 9 ? -0.6 0.1 3.1 1.9e+03 23 42 .. 427 446 .. 425 449 .. 0.83 10 ? 2.6 0.0 0.32 1.9e+02 22 42 .. 466 486 .. 462 491 .. 0.86 11 ? 2.2 0.0 0.41 2.5e+02 22 42 .. 506 526 .. 504 531 .. 0.84 12 ? 2.5 0.1 0.33 2e+02 22 42 .. 586 606 .. 584 611 .. 0.85 13 ? 1.8 0.0 0.57 3.5e+02 22 42 .. 626 646 .. 623 651 .. 0.84 14 ? 2.5 0.1 0.33 2e+02 23 43 .. 667 687 .. 664 691 .. 0.84 15 ? -2.1 0.1 9.1 5.5e+03 23 35 .. 747 759 .. 745 766 .. 0.78 16 ? -0.2 0.0 2.3 1.4e+03 23 42 .. 787 806 .. 785 811 .. 0.82 17 ? 1.3 0.1 0.82 5e+02 22 34 .. 826 838 .. 824 842 .. 0.83 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.012 Mre11_C_bact 18 keYLkkReenhekLLkiLDeLLD 40 k Y +k e hek Lk+ eL D FUN_002341-T1 22 KGYFRKAIEYHEKHLKVTMELGD 44 78***************999976 PP == domain 2 score: -1.9 bits; conditional E-value: 8 Mre11_C_bact 23 kReenhekLLkiL 35 k e hek L i FUN_002341-T1 107 KAIEYHEKHLEIA 119 66799****9996 PP == domain 3 score: 3.6 bits; conditional E-value: 0.16 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek ki e+ D v FUN_002341-T1 186 RKAIEYHEKHFKIAKEVSDRV 206 577799**********99988 PP == domain 4 score: 0.3 bits; conditional E-value: 1.6 Mre11_C_bact 23 kReenhekLLkiLDeLLDev 42 k e +ek L i+ e+ D v FUN_002341-T1 227 KAIEYYEKCLEIVKEVSDRV 246 667999*********99988 PP == domain 5 score: -0.6 bits; conditional E-value: 3.1 Mre11_C_bact 23 kReenhekLLkiLDeLLDev 42 k e hek L + e+ D v FUN_002341-T1 267 KAIEYHEKHLELAKEVSDRV 286 66799*****9999998877 PP == domain 6 score: 2.6 bits; conditional E-value: 0.32 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002341-T1 306 RKAIEYHEKHLEIAKEVSDRV 326 577799**********99988 PP == domain 7 score: 3.0 bits; conditional E-value: 0.24 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002341-T1 346 RKAIEYHEKHLEIAKEVSDRV 366 577799**********99988 PP == domain 8 score: 0.0 bits; conditional E-value: 2 Mre11_C_bact 23 kReenhekLLkiLDeLLDev 42 k e +ek L i+ e+ D v FUN_002341-T1 387 KAIEYYEKCLEIVKEVSDRV 406 667999*********99987 PP == domain 9 score: -0.6 bits; conditional E-value: 3.1 Mre11_C_bact 23 kReenhekLLkiLDeLLDev 42 k e hek L + e+ D v FUN_002341-T1 427 KAIEYHEKHLELAKEVSDRV 446 66799*****9999998877 PP == domain 10 score: 2.6 bits; conditional E-value: 0.32 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002341-T1 466 RKAIEYHEKHLEIAKEVSDRV 486 577799**********99988 PP == domain 11 score: 2.2 bits; conditional E-value: 0.41 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002341-T1 506 RKAIEYHEKHLEIAKEVRDGV 526 577799**********99987 PP == domain 12 score: 2.5 bits; conditional E-value: 0.33 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002341-T1 586 RKAIEYHEKHLEIAKEVSDRV 606 577799**********99988 PP == domain 13 score: 1.8 bits; conditional E-value: 0.57 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002341-T1 626 QKAIEYHEKDLEIAKEVSDRV 646 577799**********99988 PP == domain 14 score: 2.5 bits; conditional E-value: 0.33 Mre11_C_bact 23 kReenhekLLkiLDeLLDevk 43 k e hek L i e+ D v FUN_002341-T1 667 KAIEYHEKHLEIAKEVSDRVG 687 66799***********99985 PP == domain 15 score: -2.1 bits; conditional E-value: 9.1 Mre11_C_bact 23 kReenhekLLkiL 35 k e hek L i FUN_002341-T1 747 KAIEYHEKRLEIA 759 66799***99986 PP == domain 16 score: -0.2 bits; conditional E-value: 2.3 Mre11_C_bact 23 kReenhekLLkiLDeLLDev 42 k e hek L + e+ D v FUN_002341-T1 787 KAIEYHEKHLELAKEVSDRV 806 66799******999999988 PP == domain 17 score: 1.3 bits; conditional E-value: 0.82 Mre11_C_bact 22 kkReenhekLLki 34 +k e hek Lki FUN_002341-T1 826 RKAIEYHEKCLKI 838 577799******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1342 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 624 (0.0244275); expected 510.9 (0.02) Passed bias filter: 570 (0.0223136); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 50 (0.00195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 42 [number of targets reported over threshold] # CPU time: 0.71u 0.41s 00:00:01.11 Elapsed: 00:00:00.50 # Mc/sec: 10735.87 // Query: FUN_002342-T1 [L=244] Description: FUN_002342 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.011 16.0 0.1 0.017 15.5 0.1 1.4 1 GatB_Yqey GatB domain 0.036 14.6 0.4 0.16 12.5 0.1 2.2 1 QRICH1 QRICH1 domain Domain annotation for each model (and alignments): >> GatB_Yqey GatB domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.1 1.4e-06 0.017 12 72 .. 35 95 .. 15 128 .. 0.90 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 1.4e-06 GatB_Yqey 12 dakkaanwllgellgelnkegleieelkltpeelaellklieegkIsgkiakevleellen 72 + k+ ++w l+++ ++l+k++++ + l ++p+el+ +l+++ ++ +++ +k + ++++++ FUN_002342-T1 35 NTKTQTSWGLKKFTQWLEKRKIDCDLLTVSPAELNGILRRFYAEVKTNQVIKVICRTIFQK 95 678999*******************************************999999999876 PP >> QRICH1 QRICH1 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 1.2e-05 0.16 34 65 .. 51 82 .. 31 94 .. 0.77 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.2e-05 QRICH1 34 rkslrlkedlLslsaeeLnyaLslfvkevrrp 65 ++ +++ dlL++s++eLn +L +f ev+ + FUN_002342-T1 51 LEKRKIDCDLLTVSPAELNGILRRFYAEVKTN 82 46678999*********************976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (244 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1548 (0.0605989); expected 510.9 (0.02) Passed bias filter: 641 (0.025093); expected 510.9 (0.02) Passed Vit filter: 45 (0.0017616); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.29u 0.42s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 2358.40 // Query: FUN_002343-T1 [L=131] Description: FUN_002343 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (131 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 956 (0.0374242); expected 510.9 (0.02) Passed bias filter: 599 (0.0234488); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.41 # Mc/sec: 1298.25 // Query: FUN_002344-T1 [L=64] Description: FUN_002344 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-06 28.0 1.3 2.1e-06 27.5 1.3 1.3 1 Pr_beta_C Proteasome beta subunits C terminal Domain annotation for each model (and alignments): >> Pr_beta_C Proteasome beta subunits C terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.5 1.3 8.4e-11 2.1e-06 1 18 [. 46 63 .. 46 64 .] 0.96 Alignments for each domain: == domain 1 score: 27.5 bits; conditional E-value: 8.4e-11 Pr_beta_C 1 PNergeRqgsYkfkrGTT 18 +N +g Rqg+Y +krGTT FUN_002344-T1 46 ANDKGVRQGRYSYKRGTT 63 8***************** PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (64 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 312 (0.0122137); expected 510.9 (0.02) Passed bias filter: 297 (0.0116265); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 653.80 // Query: FUN_002345-T1 [L=1223] Description: FUN_002345 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.9e-157 511.7 44.1 2e-17 63.6 0.2 11.0 11 TPR_12 Tetratricopeptide repeat 2.5e-147 467.1 32.1 3e-08 33.6 0.0 18.7 18 TPR_7 Tetratricopeptide repeat 9.3e-132 424.6 99.5 7.4e-08 32.4 0.3 19.8 19 TPR_1 Tetratricopeptide repeat 3.1e-98 319.8 31.8 9.7e-06 25.9 0.0 19.3 19 TPR_10 Tetratricopeptide repeat 3e-90 289.3 81.0 9.7e-07 29.0 0.1 19.6 19 TPR_8 Tetratricopeptide repeat 1.1e-60 197.2 85.5 0.00098 19.6 0.1 20.3 20 TPR_2 Tetratricopeptide repeat 8e-49 167.1 0.0 1.2e-48 166.5 0.0 1.2 1 CHAT CHAT domain 1.9e-28 96.5 30.9 1.6 10.2 0.0 18.5 17 TPR_14 Tetratricopeptide repeat 4e-28 97.8 38.2 0.91 10.1 0.0 18.1 18 Rapsyn_N Rapsyn N-terminal myristoylation and lin 4.1e-25 86.4 44.9 3.7 8.5 0.0 19.4 19 TPR_17 Tetratricopeptide repeat 1.3e-24 87.6 0.6 1e-05 25.5 0.0 6.8 7 TPR_MalT MalT-like TPR region 1.6e-15 57.1 26.2 1e+02 4.4 0.0 17.5 17 TPR_6 Tetratricopeptide repeat 5.2e-13 48.9 0.6 35 4.6 0.0 15.0 18 DBD_Tnp_Mut MuDR family transposase 5.3e-13 48.7 28.6 9.2 7.3 0.1 15.0 15 PPR PPR repeat 1.2e-11 44.9 0.0 1.7e+02 2.9 0.0 14.3 17 DUF2977 Protein of unknown function (DUF2977) 3.1e-11 44.0 31.6 0.091 13.7 0.1 13.8 13 TPR_16 Tetratricopeptide repeat 4.7e-11 43.2 32.7 3.6 7.7 1.0 15.1 14 RPN7 26S proteasome subunit RPN7 3.2e-10 40.3 4.3 7.5 6.3 0.1 8.5 11 TPR_NPHP3 Nephrocystin-3 TPR domain 4.6e-10 40.0 0.4 21 5.8 0.0 9.5 13 WH_Halo_primase Halobacteria primase winged helix domain 1.1e-09 38.7 16.7 0.02 14.9 0.0 5.3 9 SNAP Soluble NSF attachment protein, SNAP 1.4e-09 38.2 0.0 74 4.9 0.0 12.4 13 TPR_4 Tetratricopeptide repeat 1.5e-08 35.5 25.6 78 4.0 0.0 15.8 18 ARM_TT21_4th Tetratricopeptide repeat protein 21 fort 6.8e-08 33.2 14.9 9.3 7.1 0.0 11.3 13 TPR_19 Tetratricopeptide repeat 6.2e-07 29.8 23.7 60 4.3 0.0 14.4 13 TPR_9 Tetratricopeptide repeat 7.6e-07 29.3 10.5 69 3.2 0.0 13.2 17 TPR_15 Tetratricopeptide repeat 1.5e-06 28.9 18.3 25 5.7 0.0 12.1 13 GGDEF_2 GGDEF-like domain 5.2e-05 22.5 11.2 5 6.1 0.1 7.3 6 TPR_IF140-IFT172 IF140/IFT172 TPR domain 0.00028 21.0 6.4 76 3.2 0.0 9.6 16 DUF6377 Domain of unknown function (DUF6377) 0.00029 20.6 0.1 23 4.5 0.0 5.5 5 Sec1 Sec1 family 0.0017 18.7 5.3 79 3.8 0.0 7.5 7 YebG YebG protein 0.0086 16.9 0.2 61 4.4 0.0 5.8 7 DHR-2_Lobe_A DHR-2, Lobe A ------ inclusion threshold ------ 0.15 12.7 0.0 2.6e+02 2.2 0.0 5.0 5 REGB_T4 T4-page Endoribonuclease RegB 0.65 10.5 20.5 98 3.5 0.0 9.6 11 Mre11_C_bact Mre11 C-terminal domain, bacteria 0.98 10.1 5.8 3.2e+02 2.0 0.0 6.4 5 FbpC_C_terminal FbpC C-terminal regulatory nucleotide bi 1.1 9.9 30.1 40 5.0 0.4 11.0 11 TPR_3 Tetratricopeptide repeat 1.2 10.0 16.2 66 4.4 0.1 8.5 8 CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA rec Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.1 1.0 4.1e-15 2.9e-12 8 75 .. 15 80 .. 11 82 .. 0.96 2 ! 63.6 0.2 2.8e-20 2e-17 4 77 .] 91 162 .. 88 162 .. 0.97 3 ! 59.7 0.2 4.6e-19 3.3e-16 4 75 .. 171 240 .. 168 242 .. 0.96 4 ! 59.0 0.2 7.7e-19 5.4e-16 4 77 .] 251 322 .. 248 322 .. 0.97 5 ! 60.9 0.2 2e-19 1.4e-16 4 77 .] 331 402 .. 328 402 .. 0.97 6 ! 58.3 0.2 1.3e-18 9.1e-16 4 75 .. 411 480 .. 408 482 .. 0.96 7 ! 54.4 0.2 2.1e-17 1.5e-14 4 75 .. 491 560 .. 488 562 .. 0.95 8 ! 60.1 0.2 3.5e-19 2.5e-16 4 77 .] 571 642 .. 568 642 .. 0.96 9 ! 36.5 0.6 8e-12 5.7e-09 21 75 .. 628 680 .. 628 682 .. 0.97 10 ! 62.6 0.7 5.7e-20 4e-17 4 77 .] 651 722 .. 648 722 .. 0.97 11 ! 49.7 0.1 6.2e-16 4.4e-13 4 71 .. 691 756 .. 688 762 .. 0.92 Alignments for each domain: == domain 1 score: 47.1 bits; conditional E-value: 4.1e-15 TPR_12 8 nlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 nlA + + lg++ +A++++ek le+a ++ +++ ++ a+ nLg +y+ l d+++A+e++++ eia FUN_002345-T1 15 NLAYAFQSLGNFRKAIKYHEKHLEIAIEA--GHRVGEGSAYGNLGNAYQSLCDFRKAIEYHQKHFEIA 80 8*************************999..99*******************************9997 PP == domain 2 score: 63.6 bits; conditional E-value: 2.8e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl++++r lg++ +A+e+++k le+a+++ d+ ++ a+ Lg +y+ lgd+++A+e++e++leia++ FUN_002345-T1 91 NAYGNLGNAYRSLGDFRKAIEYHDKHLEIAKEV--SDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKE 162 799******************************..9***********************************986 PP == domain 3 score: 59.7 bits; conditional E-value: 4.6e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++e+ le+a ++ +++ ++ +a+ Lg +y+ lgd+++A+e++e++leia FUN_002345-T1 171 SAYGNLGNTYQSLGDFRKAIEYHEERLEIAIEV--GNRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKCLEIA 240 7999*****************************..99*********************************98 PP == domain 4 score: 59.0 bits; conditional E-value: 7.7e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+++++ lg++ +A+e++ek+le+a+++ d ++ a+ nLg +y+ + d+++A++++ + leia++ FUN_002345-T1 251 SAYGNLGNAYWSLGDFRKAIEYHEKCLEIATEV--SDQVGEGSAYGNLGVAYQSMADFRKAIQYHDKHLEIARE 322 7999*****************************..9***********************************986 PP == domain 5 score: 60.9 bits; conditional E-value: 2e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+ +++ lg++ +A+e+++k le+a+++ d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia++ FUN_002345-T1 331 SAYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEV--SDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKE 402 7999*****************************..9***********************************986 PP == domain 6 score: 58.3 bits; conditional E-value: 1.3e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ nl+++++ lg++ +A+e++ek le+a+++ d+ ++ a+ Lg +y lg++++A+e++e+ leia FUN_002345-T1 411 SAYGNLGNTYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGSLGNAYKSLGNFRKAIEYHEERLEIA 480 7999*****************************..9**********************************98 PP == domain 7 score: 54.4 bits; conditional E-value: 2.1e-17 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l++++r lg++ +A+e++ek+le+a ++ ++ ++ a+ nLg +++ lgd+++A+e++++ eia FUN_002345-T1 491 NAYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEA--SHRVGEGSAYGNLGNAFQSLGDFRKAIEYHQKHFEIA 560 78989*************************999..9********************************9997 PP == domain 8 score: 60.1 bits; conditional E-value: 3.5e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+ +++ lg++ +A+e++ek le+a ++ +++ ++ +a+ nLg++y lgd+++A+e+ e+ leia++ FUN_002345-T1 571 NAYGSLGIAYQSLGDFRKAIEYHEKHLEIAIEV--GNRVGEGNAYGNLGIAYDSLGDFRKAIEYQEKRLEIAKE 642 78988****************************..99**********************************986 PP == domain 9 score: 36.5 bits; conditional E-value: 8e-12 TPR_12 21 eAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +A+e++ek le+a+++ d+ ++ +a+ nLg +y+ lgd+++A+e++ + leia FUN_002345-T1 628 KAIEYQEKRLEIAKEV--SDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIA 680 69**************..9**********************************98 PP == domain 10 score: 62.6 bits; conditional E-value: 5.7e-20 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ nl+++++ lg++ +A+e++ k le+a ++ +++ ++ ++ nLg +y+ lgd+++A+e++e+ leia++ FUN_002345-T1 651 NAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEV--GHRVGEGSTYGNLGNAYQSLGDFQKAVEYHEKHLEIAKE 722 799******************************..99**********************************986 PP == domain 11 score: 49.7 bits; conditional E-value: 6.2e-16 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqa 71 +++ nl+++++ lg++++A e++ek le+a+++ +d+ ++ +a++n g+ y+ lg++e Al+ + a FUN_002345-T1 691 STYGNLGNAYQSLGDFQKAVEYHEKHLEIAKEV--GDRAGEGIAYHNVGEEYFCLGQFENALDNFVYA 756 7999*****************************..99*************************988555 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 6.7e-07 0.00048 3 35 .. 14 46 .. 13 47 .. 0.92 2 ! 15.3 0.0 3.2e-05 0.023 1 35 [. 52 86 .. 52 87 .. 0.90 3 ! 32.0 0.0 1.4e-10 1e-07 1 35 [. 92 126 .. 92 127 .. 0.96 4 ! 29.9 0.0 6.3e-10 4.5e-07 1 35 [. 132 166 .. 132 167 .. 0.95 5 ! 25.8 0.0 1.3e-08 9.5e-06 1 35 [. 172 206 .. 172 207 .. 0.93 6 ! 27.7 0.0 3.3e-09 2.3e-06 1 35 [. 212 246 .. 212 247 .. 0.92 7 ! 28.5 0.0 1.9e-09 1.3e-06 1 34 [. 252 285 .. 252 287 .. 0.94 8 ! 25.5 0.0 1.7e-08 1.2e-05 1 35 [. 292 326 .. 292 327 .. 0.96 9 ! 28.6 0.0 1.6e-09 1.2e-06 1 35 [. 332 366 .. 332 367 .. 0.96 10 ! 30.6 0.0 3.8e-10 2.7e-07 1 35 [. 372 406 .. 372 407 .. 0.95 11 ! 31.8 0.0 1.6e-10 1.1e-07 1 35 [. 412 446 .. 412 447 .. 0.96 12 ! 22.7 0.0 1.3e-07 9.5e-05 1 35 [. 452 486 .. 452 487 .. 0.92 13 ! 27.1 0.1 5.2e-09 3.7e-06 1 34 [. 492 525 .. 492 527 .. 0.90 14 ! 20.6 0.0 6.4e-07 0.00045 1 35 [. 532 566 .. 532 567 .. 0.90 15 ! 25.0 0.0 2.4e-08 1.7e-05 1 35 [. 572 606 .. 572 607 .. 0.92 16 ! 20.6 0.0 6.4e-07 0.00045 1 35 [. 612 646 .. 612 647 .. 0.96 17 ! 26.6 0.0 7.6e-09 5.4e-06 1 35 [. 652 686 .. 652 687 .. 0.94 18 ! 33.6 0.0 4.2e-11 3e-08 1 36 [] 692 727 .. 692 727 .. 0.95 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 6.7e-07 TPR_7 3 saLariyrklGdydeAirlyerlLalakdpedr 35 +La ++++lG++++Ai+++e++L++a + ++r FUN_002345-T1 14 QNLAYAFQSLGNFRKAIKYHEKHLEIAIEAGHR 46 69************************9887776 PP == domain 2 score: 15.3 bits; conditional E-value: 3.2e-05 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++l d+++Ai++++++ ++a + ++r FUN_002345-T1 52 AYGNLGNAYQSLCDFRKAIEYHQKHFEIAIEVGHR 86 789*********************99998877776 PP == domain 3 score: 32.0 bits; conditional E-value: 1.4e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai++++++L++ak+ +dr FUN_002345-T1 92 AYGNLGNAYRSLGDFRKAIEYHDKHLEIAKEVSDR 126 789****************************9998 PP == domain 4 score: 29.9 bits; conditional E-value: 6.3e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002345-T1 132 AYGSLGNAYQSLGDFRKAIEYHEKCLEIAKEVSDR 166 7899***************************9998 PP == domain 5 score: 25.8 bits; conditional E-value: 1.3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L++a + ++r FUN_002345-T1 172 AYGNLGNTYQSLGDFRKAIEYHEERLEIAIEVGNR 206 789*************************9888776 PP == domain 6 score: 27.7 bits; conditional E-value: 3.3e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++yr+lGd+++Ai+++e++L++a + ++r FUN_002345-T1 212 AYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEAGHR 246 7899************************9887776 PP == domain 7 score: 28.5 bits; conditional E-value: 1.9e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L+++y +lGd+++Ai+++e++L++a + +d FUN_002345-T1 252 AYGNLGNAYWSLGDFRKAIEYHEKCLEIATEVSD 285 789**************************99887 PP == domain 8 score: 25.5 bits; conditional E-value: 1.7e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y+++ d+++Ai++++++L++a++ +dr FUN_002345-T1 292 AYGNLGVAYQSMADFRKAIQYHDKHLEIAREVSDR 326 789****************************9998 PP == domain 9 score: 28.6 bits; conditional E-value: 1.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai++++++L++ak+ +dr FUN_002345-T1 332 AYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEVSDR 366 789****************************9998 PP == domain 10 score: 30.6 bits; conditional E-value: 3.8e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002345-T1 372 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 406 7899***************************9998 PP == domain 11 score: 31.8 bits; conditional E-value: 1.6e-10 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e++L++ak+ +dr FUN_002345-T1 412 AYGNLGNTYQSLGDFRKAIEYHEKHLEIAKEVSDR 446 789****************************9998 PP == domain 12 score: 22.7 bits; conditional E-value: 1.3e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y +lG++++Ai+++e+ L++a + ++r FUN_002345-T1 452 AYGSLGNAYKSLGNFRKAIEYHEERLEIAIEVGNR 486 7899************************9888776 PP == domain 13 score: 27.1 bits; conditional E-value: 5.2e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdped 34 a+++L+++yr+lGd+++Ai+++e++L++a + ++ FUN_002345-T1 492 AYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEASH 525 7899***********************9977665 PP == domain 14 score: 20.6 bits; conditional E-value: 6.4e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L++++++lGd+++Ai++++++ ++a + ++r FUN_002345-T1 532 AYGNLGNAFQSLGDFRKAIEYHQKHFEIAIEVGHR 566 789*********************99998877776 PP == domain 15 score: 25.0 bits; conditional E-value: 2.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y++lGd+++Ai+++e++L++a + ++r FUN_002345-T1 572 AYGSLGIAYQSLGDFRKAIEYHEKHLEIAIEVGNR 606 7899************************9888876 PP == domain 16 score: 20.6 bits; conditional E-value: 6.4e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+ +y +lGd+++Ai++ e+ L++ak+ +dr FUN_002345-T1 612 AYGNLGIAYDSLGDFRKAIEYQEKRLEIAKEVSDR 646 789****************************9998 PP == domain 17 score: 26.6 bits; conditional E-value: 7.6e-09 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++ ++L++a + ++r FUN_002345-T1 652 AYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGHR 686 789*************************9988876 PP == domain 18 score: 33.6 bits; conditional E-value: 4.2e-11 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 ++++L+++y++lGd+++A++++e++L++ak+ +dr+ FUN_002345-T1 692 TYGNLGNAYQSLGDFQKAVEYHEKHLEIAKEVGDRA 727 578*******************************96 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 1.3 5.9e-07 0.00042 2 30 .. 11 39 .. 10 40 .. 0.94 2 ! 22.9 0.4 1e-07 7.3e-05 3 30 .. 52 79 .. 50 80 .. 0.91 3 ! 30.3 0.4 4.7e-10 3.3e-07 2 31 .. 91 120 .. 90 122 .. 0.94 4 ! 30.7 0.3 3.6e-10 2.5e-07 3 31 .. 132 160 .. 130 162 .. 0.94 5 ! 23.8 0.1 5.5e-08 3.9e-05 3 26 .. 172 195 .. 170 200 .. 0.91 6 ! 30.4 0.3 4.5e-10 3.2e-07 2 30 .. 211 239 .. 210 240 .. 0.95 7 ! 32.4 0.3 1e-10 7.4e-08 3 30 .. 252 279 .. 250 280 .. 0.96 8 ! 22.5 0.1 1.4e-07 0.0001 3 31 .. 292 320 .. 290 322 .. 0.94 9 ! 28.6 0.1 1.6e-09 1.2e-06 3 31 .. 332 360 .. 330 362 .. 0.94 10 ! 27.8 0.2 3e-09 2.1e-06 3 31 .. 372 400 .. 370 402 .. 0.94 11 ! 30.0 0.1 5.9e-10 4.2e-07 3 31 .. 412 440 .. 410 442 .. 0.94 12 ! 21.1 0.2 3.9e-07 0.00028 3 26 .. 452 475 .. 450 480 .. 0.91 13 ! 30.4 0.3 4.5e-10 3.2e-07 2 30 .. 491 519 .. 490 520 .. 0.95 14 ! 24.4 0.1 3.5e-08 2.5e-05 3 30 .. 532 559 .. 530 560 .. 0.91 15 ! 25.3 0.2 1.8e-08 1.3e-05 2 30 .. 571 599 .. 570 600 .. 0.95 16 ! 19.5 0.3 1.2e-06 0.00087 2 23 .. 611 632 .. 610 637 .. 0.96 17 ! 26.6 0.8 6.8e-09 4.8e-06 2 30 .. 651 679 .. 650 680 .. 0.94 18 ! 29.6 0.2 8.1e-10 5.8e-07 3 31 .. 692 720 .. 691 722 .. 0.94 19 ! 12.0 0.2 0.00028 0.2 3 28 .. 732 757 .. 730 759 .. 0.90 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 5.9e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 k + nl++a+++lg++ +A++y ek Le+ FUN_002345-T1 11 KGYQNLAYAFQSLGNFRKAIKYHEKHLEI 39 5799***********************98 PP == domain 2 score: 22.9 bits; conditional E-value: 1e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay++l ++ +A+ey +k e+ FUN_002345-T1 52 AYGNLGNAYQSLCDFRKAIEYHQKHFEI 79 9*********************997665 PP == domain 3 score: 30.3 bits; conditional E-value: 4.7e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ nlGnay++lg++ +A+ey +k Le+ FUN_002345-T1 91 NAYGNLGNAYRSLGDFRKAIEYHDKHLEIA 120 69**************************96 PP == domain 4 score: 30.7 bits; conditional E-value: 3.6e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek+Le+ FUN_002345-T1 132 AYGSLGNAYQSLGDFRKAIEYHEKCLEIA 160 89*************************96 PP == domain 5 score: 23.8 bits; conditional E-value: 5.5e-08 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ nlGn+y++lg++ +A+ey e+ FUN_002345-T1 172 AYGNLGNTYQSLGDFRKAIEYHEE 195 9********************886 PP == domain 6 score: 30.4 bits; conditional E-value: 4.5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey ek+Le+ FUN_002345-T1 211 NAYGSLGNAYRSLGDFRKAIEYHEKCLEI 239 59**************************8 PP == domain 7 score: 32.4 bits; conditional E-value: 1e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGnay +lg++ +A+ey ek+Le+ FUN_002345-T1 252 AYGNLGNAYWSLGDFRKAIEYHEKCLEI 279 9**************************8 PP == domain 8 score: 22.5 bits; conditional E-value: 1.4e-07 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlG+ay+++ ++ +A++y +k Le+ FUN_002345-T1 292 AYGNLGVAYQSMADFRKAIQYHDKHLEIA 320 9**************************97 PP == domain 9 score: 28.6 bits; conditional E-value: 1.6e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlG+ay++lg++ +A+ey +k Le+ FUN_002345-T1 332 AYGNLGVAYQSLGDFRKAIEYHDKHLEIA 360 9**************************96 PP == domain 10 score: 27.8 bits; conditional E-value: 3e-09 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ lGnay++lg++ +A+ey ek Le+ FUN_002345-T1 372 AYGSLGNAYQSLGDFRKAIEYHEKHLEIA 400 89*************************96 PP == domain 11 score: 30.0 bits; conditional E-value: 5.9e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 a+ nlGn+y++lg++ +A+ey ek Le+ FUN_002345-T1 412 AYGNLGNTYQSLGDFRKAIEYHEKHLEIA 440 9**************************96 PP == domain 12 score: 21.1 bits; conditional E-value: 3.9e-07 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ lGnay +lg++ +A+ey e+ FUN_002345-T1 452 AYGSLGNAYKSLGNFRKAIEYHEE 475 89*******************886 PP == domain 13 score: 30.4 bits; conditional E-value: 4.5e-10 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGnay++lg++ +A+ey ek+Le+ FUN_002345-T1 491 NAYGSLGNAYRSLGDFRKAIEYHEKCLEI 519 59**************************8 PP == domain 14 score: 24.4 bits; conditional E-value: 3.5e-08 TPR_1 3 alynlGnayfklgkydeAleyyekALel 30 a+ nlGna+++lg++ +A+ey +k e+ FUN_002345-T1 532 AYGNLGNAFQSLGDFRKAIEYHQKHFEI 559 9*********************997665 PP == domain 15 score: 25.3 bits; conditional E-value: 1.8e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lG ay++lg++ +A+ey ek Le+ FUN_002345-T1 571 NAYGSLGIAYQSLGDFRKAIEYHEKHLEI 599 59*************************98 PP == domain 16 score: 19.5 bits; conditional E-value: 1.2e-06 TPR_1 2 kalynlGnayfklgkydeAley 23 +a+ nlG ay +lg++ +A+ey FUN_002345-T1 611 NAYGNLGIAYDSLGDFRKAIEY 632 69*******************8 PP == domain 17 score: 26.6 bits; conditional E-value: 6.8e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ nlGnay++lg++ +A+ey k Le+ FUN_002345-T1 651 NAYGNLGNAYQSLGDFRKAIEYHAKHLEI 679 69********************9999998 PP == domain 18 score: 29.6 bits; conditional E-value: 8.1e-10 TPR_1 3 alynlGnayfklgkydeAleyyekALeln 31 ++ nlGnay++lg++++A+ey ek Le+ FUN_002345-T1 692 TYGNLGNAYQSLGDFQKAVEYHEKHLEIA 720 699************************96 PP == domain 19 score: 12.0 bits; conditional E-value: 0.00028 TPR_1 3 alynlGnayfklgkydeAleyyekAL 28 a+ n G yf lg+++ Al+ + A+ FUN_002345-T1 732 AYHNVGEEYFCLGQFENALDNFVYAV 757 9*******************997665 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.2 0.0019 1.4 5 33 .. 13 41 .. 13 43 .. 0.90 2 ! 8.4 0.0 0.0045 3.2 3 32 .. 51 80 .. 50 83 .. 0.87 3 ! 19.1 0.0 1.9e-06 0.0014 4 35 .. 92 123 .. 90 126 .. 0.94 4 ! 25.1 0.0 2.5e-08 1.7e-05 3 35 .. 131 163 .. 130 166 .. 0.95 5 ! 19.1 0.0 1.9e-06 0.0014 3 34 .. 171 202 .. 170 203 .. 0.91 6 ! 21.4 0.1 3.6e-07 0.00026 4 34 .. 212 242 .. 210 243 .. 0.93 7 ! 25.9 0.0 1.4e-08 9.7e-06 3 35 .. 251 283 .. 250 285 .. 0.95 8 ! 15.6 0.0 2.5e-05 0.017 3 35 .. 291 323 .. 290 326 .. 0.95 9 ! 18.7 0.0 2.5e-06 0.0018 3 35 .. 331 363 .. 330 366 .. 0.95 10 ! 18.1 0.0 4e-06 0.0029 3 35 .. 371 403 .. 370 406 .. 0.95 11 ! 21.6 0.0 3.1e-07 0.00022 3 35 .. 411 443 .. 410 446 .. 0.95 12 ! 14.6 0.0 4.9e-05 0.034 3 34 .. 451 482 .. 450 483 .. 0.91 13 ! 21.6 0.0 3e-07 0.00022 4 34 .. 492 522 .. 490 524 .. 0.93 14 ! 12.1 0.0 0.00031 0.22 3 32 .. 531 560 .. 530 563 .. 0.87 15 ! 13.3 0.0 0.00013 0.089 4 35 .. 572 603 .. 570 603 .. 0.91 16 ! 15.9 0.0 1.9e-05 0.013 4 35 .. 612 643 .. 610 646 .. 0.94 17 ! 15.9 0.1 1.9e-05 0.013 4 34 .. 652 682 .. 650 683 .. 0.90 18 ! 23.8 0.0 6.1e-08 4.4e-05 3 35 .. 691 723 .. 690 723 .. 0.96 19 ? 2.9 0.0 0.24 1.7e+02 4 23 .. 732 751 .. 731 754 .. 0.92 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0019 TPR_10 5 lnnLanalraqgryeeAeelleealaire 33 + nLa a +++g++ A +++e+ l+i+ FUN_002345-T1 13 YQNLAYAFQSLGNFRKAIKYHEKHLEIAI 41 67********************9988876 PP == domain 2 score: 8.4 bits; conditional E-value: 0.0045 TPR_10 3 sslnnLanalraqgryeeAeelleealair 32 s++ nL+na++++ ++ A e++++ ++i+ FUN_002345-T1 51 SAYGNLGNAYQSLCDFRKAIEYHQKHFEIA 80 799********************9866665 PP == domain 3 score: 19.1 bits; conditional E-value: 1.9e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+na+r++g++ A e++++ l+i+++v FUN_002345-T1 92 AYGNLGNAYRSLGDFRKAIEYHDKHLEIAKEV 123 89***************************998 PP == domain 4 score: 25.1 bits; conditional E-value: 2.5e-08 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+na++++g++ A e++e++l+i+++v FUN_002345-T1 131 SAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKEV 163 6899***************************98 PP == domain 5 score: 19.1 bits; conditional E-value: 1.9e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ nL+n+++++g++ A e++ee l+i+ + FUN_002345-T1 171 SAYGNLGNTYQSLGDFRKAIEYHEERLEIAIE 202 79***********************9888766 PP == domain 6 score: 21.4 bits; conditional E-value: 3.6e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+r++g++ A e++e++l+i+ + FUN_002345-T1 212 AYGSLGNAYRSLGDFRKAIEYHEKCLEIAIE 242 7999***********************9876 PP == domain 7 score: 25.9 bits; conditional E-value: 1.4e-08 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g++ A e++e++l+i+ +v FUN_002345-T1 251 SAYGNLGNAYWSLGDFRKAIEYHEKCLEIATEV 283 79***************************9887 PP == domain 8 score: 15.6 bits; conditional E-value: 2.5e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL++a++++ ++ A +++++ l+i+++v FUN_002345-T1 291 SAYGNLGVAYQSMADFRKAIQYHDKHLEIAREV 323 79*****************************98 PP == domain 9 score: 18.7 bits; conditional E-value: 2.5e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL++a++++g++ A e++++ l+i+++v FUN_002345-T1 331 SAYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEV 363 79****************************998 PP == domain 10 score: 18.1 bits; conditional E-value: 4e-06 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ L+na++++g++ A e++e+ l+i+++v FUN_002345-T1 371 SAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV 403 6899**************************998 PP == domain 11 score: 21.6 bits; conditional E-value: 3.1e-07 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+n+++++g++ A e++e+ l+i+++v FUN_002345-T1 411 SAYGNLGNTYQSLGDFRKAIEYHEKHLEIAKEV 443 79****************************998 PP == domain 12 score: 14.6 bits; conditional E-value: 4.9e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ L+na+ ++g++ A e++ee l+i+ + FUN_002345-T1 451 SAYGSLGNAYKSLGNFRKAIEYHEERLEIAIE 482 6899*********************9888766 PP == domain 13 score: 21.6 bits; conditional E-value: 3e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+na+r++g++ A e++e++l+i+ + FUN_002345-T1 492 AYGSLGNAYRSLGDFRKAIEYHEKCLEIAIE 522 7999************************876 PP == domain 14 score: 12.1 bits; conditional E-value: 0.00031 TPR_10 3 sslnnLanalraqgryeeAeelleealair 32 s++ nL+na +++g++ A e++++ ++i+ FUN_002345-T1 531 SAYGNLGNAFQSLGDFRKAIEYHQKHFEIA 560 799********************9966665 PP == domain 15 score: 13.3 bits; conditional E-value: 0.00013 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+ a++++g++ A e++e+ l+i+ +v FUN_002345-T1 572 AYGSLGIAYQSLGDFRKAIEYHEKHLEIAIEV 603 7999********************99998765 PP == domain 16 score: 15.9 bits; conditional E-value: 1.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ nL+ a+ ++g++ A e++e+ l+i+++v FUN_002345-T1 612 AYGNLGIAYDSLGDFRKAIEYQEKRLEIAKEV 643 89**************************9998 PP == domain 17 score: 15.9 bits; conditional E-value: 1.9e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na++++g++ A e++ + l+i+ + FUN_002345-T1 652 AYGNLGNAYQSLGDFRKAIEYHAKHLEIAIE 682 899*******************998888766 PP == domain 18 score: 23.8 bits; conditional E-value: 6.1e-08 TPR_10 3 sslnnLanalraqgryeeAeelleealairerv 35 s++ nL+na++++g+++ A+e++e+ l+i+++v FUN_002345-T1 691 STYGNLGNAYQSLGDFQKAVEYHEKHLEIAKEV 723 79***************************9987 PP == domain 19 score: 2.9 bits; conditional E-value: 0.24 TPR_10 4 slnnLanalraqgryeeAee 23 +++n + ++ +g++e A++ FUN_002345-T1 732 AYHNVGEEYFCLGQFENALD 751 79**************9986 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.5 0.00021 0.15 3 30 .. 12 39 .. 10 40 .. 0.89 2 ! 10.1 0.1 0.0015 1.1 2 23 .. 51 72 .. 50 80 .. 0.89 3 ! 18.7 0.2 2.6e-06 0.0019 3 31 .. 92 120 .. 90 122 .. 0.87 4 ! 25.9 0.1 1.3e-08 9.2e-06 2 32 .. 131 161 .. 130 163 .. 0.94 5 ! 18.2 0.1 3.9e-06 0.0028 2 26 .. 171 195 .. 170 200 .. 0.87 6 ! 24.3 0.2 4.2e-08 3e-05 3 31 .. 212 240 .. 210 240 .. 0.95 7 ! 29.0 0.1 1.4e-09 9.7e-07 2 31 .. 251 280 .. 250 282 .. 0.95 8 ! 12.3 0.1 0.00031 0.22 2 31 .. 291 320 .. 290 322 .. 0.87 9 ! 17.4 0.1 6.9e-06 0.0049 2 31 .. 331 360 .. 330 362 .. 0.87 10 ! 18.3 0.2 3.6e-06 0.0026 2 32 .. 371 401 .. 370 402 .. 0.91 11 ! 20.7 0.1 6e-07 0.00043 2 32 .. 411 441 .. 410 442 .. 0.92 12 ! 15.8 0.2 2.3e-05 0.016 2 26 .. 451 475 .. 450 480 .. 0.87 13 ! 24.3 0.2 4.2e-08 3e-05 3 31 .. 492 520 .. 490 520 .. 0.95 14 ! 14.0 0.1 8.4e-05 0.06 2 23 .. 531 552 .. 530 560 .. 0.90 15 ! 14.1 0.2 8.1e-05 0.058 3 30 .. 572 599 .. 570 600 .. 0.90 16 ! 21.0 0.3 4.9e-07 0.00035 3 32 .. 612 641 .. 610 642 .. 0.92 17 ! 17.5 0.3 6.4e-06 0.0045 3 23 .. 652 672 .. 650 680 .. 0.89 18 ! 20.1 0.1 9.7e-07 0.00069 3 32 .. 692 721 .. 690 722 .. 0.91 19 ? 3.8 0.1 0.16 1.1e+02 3 24 .. 732 753 .. 731 759 .. 0.88 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00021 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 y+nl+++ ++lg++ +A++y ek le+ FUN_002345-T1 12 GYQNLAYAFQSLGNFRKAIKYHEKHLEI 39 69*******************9987776 PP == domain 2 score: 10.1 bits; conditional E-value: 0.0015 TPR_8 2 eayynlGliylklgdyeeAkey 23 +ay nlG++y++l d+ +A+ey FUN_002345-T1 51 SAYGNLGNAYQSLCDFRKAIEY 72 59*******************9 PP == domain 3 score: 18.7 bits; conditional E-value: 2.6e-06 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay nlG++y++lgd+ +A+ey k le++ FUN_002345-T1 92 AYGNLGNAYRSLGDFRKAIEYHDKHLEIA 120 9********************77766665 PP == domain 4 score: 25.9 bits; conditional E-value: 1.3e-08 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay lG++y++lgd+ +A+ey ek+le+++ FUN_002345-T1 131 SAYGSLGNAYQSLGDFRKAIEYHEKCLEIAK 161 589**************************86 PP == domain 5 score: 18.2 bits; conditional E-value: 3.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay nlG++y++lgd+ +A+ey e+ FUN_002345-T1 171 SAYGNLGNTYQSLGDFRKAIEYHEE 195 59*******************9665 PP == domain 6 score: 24.3 bits; conditional E-value: 4.2e-08 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay lG++y++lgd+ +A+ey ek+le++ FUN_002345-T1 212 AYGSLGNAYRSLGDFRKAIEYHEKCLEIA 240 89*************************95 PP == domain 7 score: 29.0 bits; conditional E-value: 1.4e-09 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay nlG++y++lgd+ +A+ey ek+le++ FUN_002345-T1 251 SAYGNLGNAYWSLGDFRKAIEYHEKCLEIA 280 59**************************97 PP == domain 8 score: 12.3 bits; conditional E-value: 0.00031 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay nlG +y+++ d+ +A++y k le++ FUN_002345-T1 291 SAYGNLGVAYQSMADFRKAIQYHDKHLEIA 320 59*******************977777776 PP == domain 9 score: 17.4 bits; conditional E-value: 6.9e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleld 31 +ay nlG +y++lgd+ +A+ey k le++ FUN_002345-T1 331 SAYGNLGVAYQSLGDFRKAIEYHDKHLEIA 360 59********************77766665 PP == domain 10 score: 18.3 bits; conditional E-value: 3.6e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay lG++y++lgd+ +A+ey ek le+++ FUN_002345-T1 371 SAYGSLGNAYQSLGDFRKAIEYHEKHLEIAK 401 589*******************999998875 PP == domain 11 score: 20.7 bits; conditional E-value: 6e-07 TPR_8 2 eayynlGliylklgdyeeAkeyyekaleldp 32 +ay nlG++y++lgd+ +A+ey ek le+++ FUN_002345-T1 411 SAYGNLGNTYQSLGDFRKAIEYHEKHLEIAK 441 59********************999998875 PP == domain 12 score: 15.8 bits; conditional E-value: 2.3e-05 TPR_8 2 eayynlGliylklgdyeeAkeyyek 26 +ay lG++y++lg++ +A+ey e+ FUN_002345-T1 451 SAYGSLGNAYKSLGNFRKAIEYHEE 475 589******************9665 PP == domain 13 score: 24.3 bits; conditional E-value: 4.2e-08 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleld 31 ay lG++y++lgd+ +A+ey ek+le++ FUN_002345-T1 492 AYGSLGNAYRSLGDFRKAIEYHEKCLEIA 520 89*************************95 PP == domain 14 score: 14.0 bits; conditional E-value: 8.4e-05 TPR_8 2 eayynlGliylklgdyeeAkey 23 +ay nlG++ ++lgd+ +A+ey FUN_002345-T1 531 SAYGNLGNAFQSLGDFRKAIEY 552 59*******************9 PP == domain 15 score: 14.1 bits; conditional E-value: 8.1e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG +y++lgd+ +A+ey ek le+ FUN_002345-T1 572 AYGSLGIAYQSLGDFRKAIEYHEKHLEI 599 899******************9987776 PP == domain 16 score: 21.0 bits; conditional E-value: 4.9e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay nlG +y +lgd+ +A+ey ek le+++ FUN_002345-T1 612 AYGNLGIAYDSLGDFRKAIEYQEKRLEIAK 641 8***********************999875 PP == domain 17 score: 17.5 bits; conditional E-value: 6.4e-06 TPR_8 3 ayynlGliylklgdyeeAkey 23 ay nlG++y++lgd+ +A+ey FUN_002345-T1 652 AYGNLGNAYQSLGDFRKAIEY 672 9*******************9 PP == domain 18 score: 20.1 bits; conditional E-value: 9.7e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 +y nlG++y++lgd+++A+ey ek le+++ FUN_002345-T1 692 TYGNLGNAYQSLGDFQKAVEYHEKHLEIAK 721 79*******************999998875 PP == domain 19 score: 3.8 bits; conditional E-value: 0.16 TPR_8 3 ayynlGliylklgdyeeAkeyy 24 ay+n G y lg++e+A + FUN_002345-T1 732 AYHNVGEEYFCLGQFENALDNF 753 8*****************7655 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.5 0.0049 3.5 3 23 .. 12 32 .. 10 40 .. 0.91 2 ! 11.2 0.2 0.00067 0.48 3 23 .. 52 72 .. 50 75 .. 0.93 3 ! 15.1 0.3 3.8e-05 0.027 3 23 .. 92 112 .. 90 120 .. 0.94 4 ! 17.4 0.1 7e-06 0.0049 3 32 .. 132 161 .. 130 163 .. 0.91 5 ! 12.7 0.1 0.00021 0.15 3 23 .. 172 192 .. 170 195 .. 0.94 6 ! 17.1 0.2 8.5e-06 0.006 3 31 .. 212 240 .. 210 242 .. 0.92 7 ! 19.6 0.1 1.4e-06 0.00098 3 31 .. 252 280 .. 250 282 .. 0.93 8 ? 5.9 0.1 0.032 23 3 23 .. 292 312 .. 290 319 .. 0.94 9 ! 13.0 0.1 0.00018 0.13 3 23 .. 332 352 .. 330 360 .. 0.94 10 ! 12.0 0.2 0.00037 0.26 3 23 .. 372 392 .. 370 402 .. 0.87 11 ! 13.2 0.1 0.00015 0.11 3 23 .. 412 432 .. 410 442 .. 0.89 12 ! 10.8 0.1 0.00086 0.61 3 23 .. 452 472 .. 450 475 .. 0.92 13 ! 17.1 0.2 8.5e-06 0.006 3 31 .. 492 520 .. 490 522 .. 0.92 14 ! 10.8 0.1 0.00086 0.61 3 23 .. 532 552 .. 530 555 .. 0.93 15 ! 10.5 0.2 0.0011 0.78 3 23 .. 572 592 .. 570 600 .. 0.90 16 ! 14.5 0.3 5.9e-05 0.042 3 26 .. 612 635 .. 610 642 .. 0.87 17 ! 14.2 0.3 7.1e-05 0.051 3 23 .. 652 672 .. 650 672 .. 0.94 18 ! 13.9 0.1 9e-05 0.064 4 23 .. 693 712 .. 691 722 .. 0.88 19 ! 11.6 0.1 0.0005 0.35 3 29 .. 732 758 .. 730 762 .. 0.91 20 ? -1.3 0.0 7 4.9e+03 10 24 .. 791 805 .. 790 806 .. 0.83 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.0049 TPR_2 3 alynlGlayyklgdyeeAlea 23 ++ nl++a lg++ +A+++ FUN_002345-T1 12 GYQNLAYAFQSLGNFRKAIKY 32 799****************98 PP == domain 2 score: 11.2 bits; conditional E-value: 0.00067 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay l d+ +A+e+ FUN_002345-T1 52 AYGNLGNAYQSLCDFRKAIEY 72 899****************98 PP == domain 3 score: 15.1 bits; conditional E-value: 3.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay+ lgd+ +A+e+ FUN_002345-T1 92 AYGNLGNAYRSLGDFRKAIEY 112 899****************98 PP == domain 4 score: 17.4 bits; conditional E-value: 7e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleldP 32 a+ lG+ay lgd+ +A+e+ ek+le++ FUN_002345-T1 132 AYGSLGNAYQSLGDFRKAIEYHEKCLEIAK 161 6778***********************986 PP == domain 5 score: 12.7 bits; conditional E-value: 0.00021 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ y lgd+ +A+e+ FUN_002345-T1 172 AYGNLGNTYQSLGDFRKAIEY 192 899****************98 PP == domain 6 score: 17.1 bits; conditional E-value: 8.5e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ lG+ay+ lgd+ +A+e+ ek+le++ FUN_002345-T1 212 AYGSLGNAYRSLGDFRKAIEYHEKCLEIA 240 7888**********************985 PP == domain 7 score: 19.6 bits; conditional E-value: 1.4e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ nlG+ay+ lgd+ +A+e+ ek+le++ FUN_002345-T1 252 AYGNLGNAYWSLGDFRKAIEYHEKCLEIA 280 899***********************986 PP == domain 8 score: 5.9 bits; conditional E-value: 0.032 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay + d+ +A+++ FUN_002345-T1 292 AYGNLGVAYQSMADFRKAIQY 312 899****************97 PP == domain 9 score: 13.0 bits; conditional E-value: 0.00018 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG ay lgd+ +A+e+ FUN_002345-T1 332 AYGNLGVAYQSLGDFRKAIEY 352 899****************98 PP == domain 10 score: 12.0 bits; conditional E-value: 0.00037 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+ +A+e+ FUN_002345-T1 372 AYGSLGNAYQSLGDFRKAIEY 392 6778****************9 PP == domain 11 score: 13.2 bits; conditional E-value: 0.00015 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ y lgd+ +A+e+ FUN_002345-T1 412 AYGNLGNTYQSLGDFRKAIEY 432 899*****************8 PP == domain 12 score: 10.8 bits; conditional E-value: 0.00086 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lg++ +A+e+ FUN_002345-T1 452 AYGSLGNAYKSLGNFRKAIEY 472 6778***************98 PP == domain 13 score: 17.1 bits; conditional E-value: 8.5e-06 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ lG+ay+ lgd+ +A+e+ ek+le++ FUN_002345-T1 492 AYGSLGNAYRSLGDFRKAIEYHEKCLEIA 520 7888**********************985 PP == domain 14 score: 10.8 bits; conditional E-value: 0.00086 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+a lgd+ +A+e+ FUN_002345-T1 532 AYGNLGNAFQSLGDFRKAIEY 552 899****************98 PP == domain 15 score: 10.5 bits; conditional E-value: 0.0011 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG ay lgd+ +A+e+ FUN_002345-T1 572 AYGSLGIAYQSLGDFRKAIEY 592 7888***************98 PP == domain 16 score: 14.5 bits; conditional E-value: 5.9e-05 TPR_2 3 alynlGlayyklgdyeeAleayek 26 a+ nlG ay lgd+ +A+e+ ek FUN_002345-T1 612 AYGNLGIAYDSLGDFRKAIEYQEK 635 899******************988 PP == domain 17 score: 14.2 bits; conditional E-value: 7.1e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lgd+ +A+e+ FUN_002345-T1 652 AYGNLGNAYQSLGDFRKAIEY 672 899****************98 PP == domain 18 score: 13.9 bits; conditional E-value: 9e-05 TPR_2 4 lynlGlayyklgdyeeAlea 23 + nlG+ay lgd+++A+e+ FUN_002345-T1 693 YGNLGNAYQSLGDFQKAVEY 712 779***************98 PP == domain 19 score: 11.6 bits; conditional E-value: 0.0005 TPR_2 3 alynlGlayyklgdyeeAleayekAle 29 a++n G+ y+ lg++e Al+ + A+e FUN_002345-T1 732 AYHNVGEEYFCLGQFENALDNFVYAVE 758 89*******************998887 PP == domain 20 score: -1.3 bits; conditional E-value: 7 TPR_2 10 ayyklgdyeeAleay 24 ++++ g+ +eAl a FUN_002345-T1 791 SLLRIGKIDEALFAA 805 67899******9875 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 166.5 0.0 1.7e-51 1.2e-48 8 291 .] 947 1209 .. 942 1209 .. 0.88 Alignments for each domain: == domain 1 score: 166.5 bits; conditional E-value: 1.7e-51 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ +Lviv dgaL +P++a ++ i ++ps+++ +s++++ ++ a l+vgnp+ + k FUN_002345-T1 947 YDAVIGPIEDLL-APEDDELVIVSDGALCFIPWAAVIESI---------RIRIVPSLKSyqlISSVPKGYHKKTGA--LLVGNPCLEQ----LK 1024 899****99997.66667*****************88886.........466666655422255555555555555..******9774....35 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 + lp +++E++++a++l+ +l+g++at+ ++++ + ++++++H+a+Hg + + ++L++ n + ed L++++++ FUN_002345-T1 1025 NPLHALPCAQKEVEMIAAILNN---TPLVGKQATKAEVMKRM-SSVGLIHIAAHGDVV-----TGQIALSP-NPGwtqfpkeEDYILKMSDVQA 1108 55699***************87...8***************9.***************.....89999975.4445889999************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C +++g+v +g+gv g+ara+l aGa+sv++ lw dd+at ++mk+fy++l+ g ++++A+ q + +l+++++ +++ FUN_002345-T1 1109 ANLR-ARLVVLSCCHSGRGRVLKGEGVVGIARAFLAAGARSVLVALWALDDEATMEFMKRFYQHLKEGNTASAAVDQSMKSLRESEE----FSE 1197 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002345-T1 1198 MWYWAPFQLIGD 1209 ***********7 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.4 0.0 0.081 57 4 29 .. 13 38 .. 10 42 .. 0.89 2 ? 7.6 0.0 0.015 11 6 30 .. 95 119 .. 91 125 .. 0.85 3 ! 8.9 0.0 0.0058 4.1 6 31 .. 135 160 .. 131 165 .. 0.88 4 ? 4.9 0.0 0.12 82 7 29 .. 176 198 .. 171 200 .. 0.88 5 ! 10.0 0.0 0.0025 1.8 5 29 .. 214 238 .. 211 242 .. 0.89 6 ! 10.2 0.0 0.0023 1.6 6 30 .. 255 279 .. 251 284 .. 0.89 7 ? 3.8 0.0 0.26 1.8e+02 7 30 .. 336 359 .. 331 365 .. 0.85 8 ? 6.6 0.0 0.031 22 6 31 .. 375 400 .. 371 405 .. 0.86 9 ? 4.8 0.0 0.12 88 7 31 .. 416 440 .. 411 445 .. 0.86 10 ? 6.4 0.0 0.037 26 6 29 .. 455 478 .. 451 480 .. 0.89 11 ! 10.1 0.0 0.0023 1.6 5 29 .. 494 518 .. 491 525 .. 0.89 12 ? 1.6 0.0 1.3 9.1e+02 7 26 .. 536 555 .. 531 560 .. 0.84 13 ? 4.3 0.0 0.18 1.3e+02 6 29 .. 575 598 .. 571 600 .. 0.85 14 ? 0.7 0.0 2.5 1.8e+03 6 23 .. 615 632 .. 611 643 .. 0.80 15 ? 4.4 0.0 0.17 1.2e+02 6 28 .. 655 677 .. 651 680 .. 0.83 16 ? 6.0 0.0 0.051 36 7 30 .. 696 719 .. 692 725 .. 0.88 17 ? -0.6 0.0 6.8 4.9e+03 10 30 .. 791 811 .. 790 824 .. 0.74 Alignments for each domain: == domain 1 score: 5.4 bits; conditional E-value: 0.081 TPR_14 4 wlalarallalGdpdeAlellerala 29 ++ la+a+ lG++ +A+++ e+ l+ FUN_002345-T1 13 YQNLAYAFQSLGNFRKAIKYHEKHLE 38 7889****************999876 PP == domain 2 score: 7.6 bits; conditional E-value: 0.015 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a++ lGd+ +A+e+ ++ l+ FUN_002345-T1 95 NLGNAYRSLGDFRKAIEYHDKHLEI 119 699***************9998876 PP == domain 3 score: 8.9 bits; conditional E-value: 0.0058 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e++l+ FUN_002345-T1 135 SLGNAYQSLGDFRKAIEYHEKCLEIA 160 699*******************9976 PP == domain 4 score: 4.9 bits; conditional E-value: 0.12 TPR_14 7 larallalGdpdeAlellerala 29 l++++ lGd+ +A+e+ e+ l+ FUN_002345-T1 176 LGNTYQSLGDFRKAIEYHEERLE 198 8999**************99987 PP == domain 5 score: 10.0 bits; conditional E-value: 0.0025 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e++l+ FUN_002345-T1 214 GSLGNAYRSLGDFRKAIEYHEKCLE 238 5799******************998 PP == domain 6 score: 10.2 bits; conditional E-value: 0.0023 TPR_14 6 alarallalGdpdeAlelleralal 30 l++a++ lGd+ +A+e+ e++l+ FUN_002345-T1 255 NLGNAYWSLGDFRKAIEYHEKCLEI 279 589*******************985 PP == domain 7 score: 3.8 bits; conditional E-value: 0.26 TPR_14 7 larallalGdpdeAlelleralal 30 l+ a+ lGd+ +A+e+ ++ l+ FUN_002345-T1 336 LGVAYQSLGDFRKAIEYHDKHLEI 359 7889*************9998876 PP == domain 8 score: 6.6 bits; conditional E-value: 0.031 TPR_14 6 alarallalGdpdeAlelleralald 31 l++a+ lGd+ +A+e+ e+ l+ FUN_002345-T1 375 SLGNAYQSLGDFRKAIEYHEKHLEIA 400 699***************99998865 PP == domain 9 score: 4.8 bits; conditional E-value: 0.12 TPR_14 7 larallalGdpdeAlelleralald 31 l++++ lGd+ +A+e+ e+ l+ FUN_002345-T1 416 LGNTYQSLGDFRKAIEYHEKHLEIA 440 8999*************99998865 PP == domain 10 score: 6.4 bits; conditional E-value: 0.037 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lG++ +A+e+ e+ l+ FUN_002345-T1 455 SLGNAYKSLGNFRKAIEYHEERLE 478 699****************99987 PP == domain 11 score: 10.1 bits; conditional E-value: 0.0023 TPR_14 5 lalarallalGdpdeAlellerala 29 l++a++ lGd+ +A+e+ e++l+ FUN_002345-T1 494 GSLGNAYRSLGDFRKAIEYHEKCLE 518 5799*******************98 PP == domain 12 score: 1.6 bits; conditional E-value: 1.3 TPR_14 7 larallalGdpdeAleller 26 l++a+ lGd+ +A+e+ ++ FUN_002345-T1 536 LGNAFQSLGDFRKAIEYHQK 555 89999**********99765 PP == domain 13 score: 4.3 bits; conditional E-value: 0.18 TPR_14 6 alarallalGdpdeAlellerala 29 l+ a+ lGd+ +A+e+ e+ l+ FUN_002345-T1 575 SLGIAYQSLGDFRKAIEYHEKHLE 598 68899*************998876 PP == domain 14 score: 0.7 bits; conditional E-value: 2.5 TPR_14 6 alarallalGdpdeAlel 23 l+ a+ lGd+ +A+e+ FUN_002345-T1 615 NLGIAYDSLGDFRKAIEY 632 5788999*********98 PP == domain 15 score: 4.4 bits; conditional E-value: 0.17 TPR_14 6 alarallalGdpdeAlelleral 28 l++a+ lGd+ +A+e+ + l FUN_002345-T1 655 NLGNAYQSLGDFRKAIEYHAKHL 677 689**************987766 PP == domain 16 score: 6.0 bits; conditional E-value: 0.051 TPR_14 7 larallalGdpdeAlelleralal 30 l++a+ lGd+++A+e+ e+ l+ FUN_002345-T1 696 LGNAYQSLGDFQKAVEYHEKHLEI 719 899**************9999886 PP == domain 17 score: -0.6 bits; conditional E-value: 6.8 TPR_14 10 allalGdpdeAlelleralal 30 ll+ G+ deAl ++e + a+ FUN_002345-T1 791 SLLRIGKIDEALFAAEIGRAQ 811 68999*******999987765 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.3 0.1 0.35 2.5e+02 49 75 .. 16 42 .. 5 47 .. 0.85 2 ? 0.9 0.0 0.96 6.8e+02 46 76 .. 53 83 .. 44 86 .. 0.87 3 ! 8.6 0.0 0.0038 2.7 46 78 .. 93 125 .. 83 127 .. 0.90 4 ! 8.9 0.0 0.0031 2.2 44 78 .. 131 165 .. 124 167 .. 0.87 5 ? 5.4 0.0 0.039 28 36 76 .. 163 203 .. 161 207 .. 0.86 6 ? 4.0 0.0 0.1 73 46 75 .. 213 242 .. 204 245 .. 0.87 7 ? 6.3 0.0 0.02 14 46 78 .. 253 285 .. 245 287 .. 0.90 8 ! 7.9 0.0 0.0064 4.5 46 78 .. 293 325 .. 284 327 .. 0.88 9 ! 8.8 0.0 0.0033 2.4 42 78 .. 329 365 .. 323 367 .. 0.85 10 ! 10.1 0.0 0.0013 0.91 40 78 .. 367 405 .. 363 407 .. 0.86 11 ! 7.6 0.0 0.0077 5.4 44 78 .. 411 445 .. 403 447 .. 0.84 12 ! 8.2 0.0 0.005 3.5 36 76 .. 443 483 .. 441 487 .. 0.88 13 ? 4.2 0.0 0.09 64 46 75 .. 493 522 .. 484 526 .. 0.87 14 ? 4.6 0.1 0.066 47 45 76 .. 532 563 .. 521 567 .. 0.84 15 ? 5.2 0.1 0.043 31 46 76 .. 573 603 .. 564 607 .. 0.87 16 ! 8.2 0.0 0.0051 3.6 46 78 .. 613 645 .. 604 647 .. 0.88 17 ! 7.9 0.0 0.0064 4.6 35 76 .. 642 683 .. 641 687 .. 0.89 18 ? 6.5 0.1 0.017 12 46 78 .. 693 725 .. 682 727 .. 0.89 Alignments for each domain: == domain 1 score: 2.3 bits; conditional E-value: 0.35 Rapsyn_N 49 litahsemGkykealefslaqlniaee 75 l a +G ++ a+++ + l+ia e FUN_002345-T1 16 LAYAFQSLGNFRKAIKYHEKHLEIAIE 42 5668889***************99977 PP == domain 2 score: 0.9 bits; conditional E-value: 0.96 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ + ++ a+e+ + ++ia e+ FUN_002345-T1 53 YGNLGNAYQSLCDFRKAIEYHQKHFEIAIEV 83 57888999999**********9999999886 PP == domain 3 score: 8.6 bits; conditional E-value: 0.0038 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002345-T1 93 YGNLGNAYRSLGDFRKAIEYHDKHLEIAKEVSD 125 688999************************976 PP == domain 4 score: 8.9 bits; conditional E-value: 0.0031 Rapsyn_N 44 rllGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002345-T1 131 SAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKEVSD 165 56799999************************976 PP == domain 5 score: 5.4 bits; conditional E-value: 0.039 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeel 76 sdr + G l +++ +G ++ a+e+ ++l+ia e+ FUN_002345-T1 163 VSDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEERLEIAIEV 203 5677777778899999999******************9987 PP == domain 6 score: 4.0 bits; conditional E-value: 0.1 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaee 75 G l +a+ +G ++ a+e+ + l+ia e FUN_002345-T1 213 YGSLGNAYRSLGDFRKAIEYHEKCLEIAIE 242 688999****************99999976 PP == domain 7 score: 6.3 bits; conditional E-value: 0.02 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia e+ d FUN_002345-T1 253 YGNLGNAYWSLGDFRKAIEYHEKCLEIATEVSD 285 58889999*********************9976 PP == domain 8 score: 7.9 bits; conditional E-value: 0.0064 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l a+ m ++ a+++ + l+ia+e+ d FUN_002345-T1 293 YGNLGVAYQSMADFRKAIQYHDKHLEIAREVSD 325 5778889999********************976 PP == domain 9 score: 8.8 bits; conditional E-value: 0.0033 Rapsyn_N 42 kfrllGylitahsemGkykealefslaqlniaeeled 78 G l a+ +G ++ a+e+ + l+ia+e+ d FUN_002345-T1 329 EGSAYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEVSD 365 555678899999**********************976 PP == domain 10 score: 10.1 bits; conditional E-value: 0.0013 Rapsyn_N 40 edkfrllGylitahsemGkykealefslaqlniaeeled 78 + G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002345-T1 367 VGEGSAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSD 405 55556679999*************************976 PP == domain 11 score: 7.6 bits; conditional E-value: 0.0077 Rapsyn_N 44 rllGylitahsemGkykealefslaqlniaeeled 78 G l +++ +G ++ a+e+ + l+ia+e+ d FUN_002345-T1 411 SAYGNLGNTYQSLGDFRKAIEYHEKHLEIAKEVSD 445 556888889999********************976 PP == domain 12 score: 8.2 bits; conditional E-value: 0.005 Rapsyn_N 36 tsdredkfrllGylitahsemGkykealefslaqlniaeel 76 sdr + G l +a+ +G ++ a+e+ ++l+ia e+ FUN_002345-T1 443 VSDRVGEGSAYGSLGNAYKSLGNFRKAIEYHEERLEIAIEV 483 677778888899*************************9987 PP == domain 13 score: 4.2 bits; conditional E-value: 0.09 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaee 75 G l +a+ +G ++ a+e+ + l+ia e FUN_002345-T1 493 YGSLGNAYRSLGDFRKAIEYHEKCLEIAIE 522 688999*****************9999977 PP == domain 14 score: 4.6 bits; conditional E-value: 0.066 Rapsyn_N 45 llGylitahsemGkykealefslaqlniaeel 76 G l +a +G ++ a+e+ + ++ia e+ FUN_002345-T1 532 AYGNLGNAFQSLGDFRKAIEYHQKHFEIAIEV 563 5789999****************999999886 PP == domain 15 score: 5.2 bits; conditional E-value: 0.043 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G ++ a+e+ + l+ia e+ FUN_002345-T1 573 YGSLGIAYQSLGDFRKAIEYHEKHLEIAIEV 603 5778889999*****************9887 PP == domain 16 score: 8.2 bits; conditional E-value: 0.0051 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l a+ +G ++ a+e+ ++l+ia+e+ d FUN_002345-T1 613 YGNLGIAYDSLGDFRKAIEYQEKRLEIAKEVSD 645 5778889999********************976 PP == domain 17 score: 7.9 bits; conditional E-value: 0.0064 Rapsyn_N 35 ktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 + sdr + + G l +a+ +G ++ a+e+ + l+ia e+ FUN_002345-T1 642 EVSDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEV 683 5678888888899*************************9886 PP == domain 18 score: 6.5 bits; conditional E-value: 0.017 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeeled 78 G l +a+ +G ++ a+e+ + l+ia+e+ d FUN_002345-T1 693 YGNLGNAYQSLGDFQKAVEYHEKHLEIAKEVGD 725 688999************************876 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.1 0.18 1.2e+02 15 33 .. 12 30 .. 10 31 .. 0.91 2 ? 1.0 0.2 1.3 9.6e+02 15 26 .. 52 63 .. 50 82 .. 0.56 3 ! 8.4 0.1 0.0057 4 14 34 .] 91 111 .. 89 111 .. 0.93 4 ? 4.9 0.0 0.075 53 15 34 .] 132 151 .. 129 151 .. 0.91 5 ! 8.5 0.0 0.0053 3.7 14 34 .] 171 191 .. 169 191 .. 0.92 6 ? 5.5 0.0 0.049 35 14 34 .] 211 231 .. 209 231 .. 0.92 7 ? 1.5 0.0 0.91 6.5e+02 14 33 .. 251 270 .. 249 271 .. 0.88 8 ? 4.3 0.0 0.12 85 14 34 .] 291 311 .. 289 311 .. 0.93 9 ? 6.9 0.0 0.017 12 14 34 .] 331 351 .. 329 351 .. 0.92 10 ? 4.9 0.0 0.075 53 15 34 .] 372 391 .. 369 391 .. 0.91 11 ! 8.5 0.0 0.0053 3.7 14 34 .] 411 431 .. 409 431 .. 0.92 12 ? 4.4 0.0 0.11 77 15 34 .] 452 471 .. 449 471 .. 0.91 13 ? 5.5 0.0 0.049 35 14 34 .] 491 511 .. 489 511 .. 0.92 14 ? 4.1 0.0 0.13 96 14 34 .] 531 551 .. 529 551 .. 0.92 15 ? 4.8 0.0 0.085 61 14 34 .] 571 591 .. 569 591 .. 0.92 16 ? 7.1 0.0 0.015 11 14 34 .] 611 631 .. 609 631 .. 0.93 17 ! 8.4 0.1 0.0058 4.1 14 34 .] 651 671 .. 649 671 .. 0.93 18 ? 7.1 0.0 0.016 11 15 33 .. 692 710 .. 690 711 .. 0.91 19 ? -0.7 0.0 4.9 3.5e+03 15 33 .. 732 750 .. 730 751 .. 0.85 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.18 TPR_17 15 ayynLArlllnnGqleeAl 33 y+nLA++ + +G++ +A+ FUN_002345-T1 12 GYQNLAYAFQSLGNFRKAI 30 69**************998 PP == domain 2 score: 1.0 bits; conditional E-value: 1.3 TPR_17 15 ayynLArlllnn 26 ay nL+++++ + FUN_002345-T1 52 AYGNLGNAYQSL 63 677777777633 PP == domain 3 score: 8.4 bits; conditional E-value: 0.0057 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002345-T1 91 NAYGNLGNAYRSLGDFRKAIE 111 79****************985 PP == domain 4 score: 4.9 bits; conditional E-value: 0.075 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002345-T1 132 AYGSLGNAYQSLGDFRKAIE 151 899**************985 PP == domain 5 score: 8.5 bits; conditional E-value: 0.0053 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002345-T1 171 SAYGNLGNTYQSLGDFRKAIE 191 59****************985 PP == domain 6 score: 5.5 bits; conditional E-value: 0.049 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002345-T1 211 NAYGSLGNAYRSLGDFRKAIE 231 79****************985 PP == domain 7 score: 1.5 bits; conditional E-value: 0.91 TPR_17 14 dayynLArlllnnGqleeAl 33 ay nL++++ +G++ +A+ FUN_002345-T1 251 SAYGNLGNAYWSLGDFRKAI 270 59********9999999998 PP == domain 8 score: 4.3 bits; conditional E-value: 0.12 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ + ++ +A+q FUN_002345-T1 291 SAYGNLGVAYQSMADFRKAIQ 311 59*****************98 PP == domain 9 score: 6.9 bits; conditional E-value: 0.017 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002345-T1 331 SAYGNLGVAYQSLGDFRKAIE 351 59****************985 PP == domain 10 score: 4.9 bits; conditional E-value: 0.075 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002345-T1 372 AYGSLGNAYQSLGDFRKAIE 391 899**************985 PP == domain 11 score: 8.5 bits; conditional E-value: 0.0053 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++++ +G++ +A++ FUN_002345-T1 411 SAYGNLGNTYQSLGDFRKAIE 431 59****************985 PP == domain 12 score: 4.4 bits; conditional E-value: 0.11 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002345-T1 452 AYGSLGNAYKSLGNFRKAIE 471 899**************985 PP == domain 13 score: 5.5 bits; conditional E-value: 0.049 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002345-T1 491 NAYGSLGNAYRSLGDFRKAIE 511 79****************985 PP == domain 14 score: 4.1 bits; conditional E-value: 0.13 TPR_17 14 dayynLArlllnnGqleeAlq 34 ay nL+++ + +G++ +A++ FUN_002345-T1 531 SAYGNLGNAFQSLGDFRKAIE 551 59****************985 PP == domain 15 score: 4.8 bits; conditional E-value: 0.085 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002345-T1 571 NAYGSLGIAYQSLGDFRKAIE 591 79****************985 PP == domain 16 score: 7.1 bits; conditional E-value: 0.015 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL++++ +G++ +A++ FUN_002345-T1 611 NAYGNLGIAYDSLGDFRKAIE 631 79****************985 PP == domain 17 score: 8.4 bits; conditional E-value: 0.0058 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002345-T1 651 NAYGNLGNAYQSLGDFRKAIE 671 79****************985 PP == domain 18 score: 7.1 bits; conditional E-value: 0.016 TPR_17 15 ayynLArlllnnGqleeAl 33 y nL+++++ +G++++A+ FUN_002345-T1 692 TYGNLGNAYQSLGDFQKAV 710 699**************97 PP == domain 19 score: -0.7 bits; conditional E-value: 4.9 TPR_17 15 ayynLArlllnnGqleeAl 33 ay+n ++ + +Gq+e Al FUN_002345-T1 732 AYHNVGEEYFCLGQFENAL 750 8999999999999999886 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 0.00013 0.092 13 155 .. 22 163 .. 15 167 .. 0.82 2 ! 25.5 0.0 1.5e-08 1e-05 12 157 .. 141 285 .. 136 322 .. 0.90 3 ! 15.0 0.0 2.2e-05 0.015 16 155 .. 305 443 .. 296 447 .. 0.76 4 ! 16.6 0.0 7.3e-06 0.0052 11 151 .. 420 559 .. 417 567 .. 0.88 5 ! 12.8 0.0 0.00011 0.075 12 112 .. 501 602 .. 488 616 .. 0.93 6 ! 11.7 0.0 0.00023 0.16 13 113 .. 622 723 .. 616 728 .. 0.88 7 ? 2.8 0.0 0.12 83 40 69 .. 730 759 .. 725 769 .. 0.86 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00013 TPR_MalT 13 sqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+++ ++ L++ e + + ++a+ +lG a++ + d+ +A + ++ ++a + ++ a+ +++ +r G++++A+e + l FUN_002345-T1 22 SLGNFRKAIKYHEKHLEIAIEAGHRVGeGSAYGNLGNAYQSLCDFRKAIEYHQKHFEIAIEVGHRVGEGNAYGNLGNAYRSLGDFRKAIEYHDKHL 117 567888888888888888888888887789999999999999999999999998888888888888888999999999999999999999999999 PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 + a+e + + g ++ +l++ + +d+ +A ++ ++ +++++++ FUN_002345-T1 118 EIAKEVSDRV--GEGSAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKEV 163 9999988885..777888899999999999999999998888888876 PP == domain 2 score: 25.5 bits; conditional E-value: 1.5e-08 TPR_MalT 12 vsqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 s g++ +a+e+ ++ L++ +e +d ++a+ +lG +++ +gd+ +A + +e ++a + ++ a+ ++++ +r G++++A+e ++ FUN_002345-T1 141 QSLGDFRKAIEYHEKCLEIAKEvSDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEERLEIAIEVGNRVGEGNAYGSLGNAYRSLGDFRKAIEYHEKC 236 57899**************99844445559999*********************************99**************************** PP TPR_MalT 107 lqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrqlep 157 l+ a e++ + g ++ l++ ++ +d+ +A ++ ++ ++++ +++ FUN_002345-T1 237 LEIAIEAGHRV--GEGSAYGNLGNAYWSLGDFRKAIEYHEKCLEIATEVSD 285 *******9995..8889999**********************999988754 PP == domain 3 score: 15.0 bits; conditional E-value: 2.2e-05 TPR_MalT 16 eaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqla 110 ++ +a+++ + L++ +e +d ++a+ +lG+a++ +gd+ +A + + ++a++ + a+ ++++ ++ G++++A+e ++ l+ a FUN_002345-T1 305 DFRKAIQYHDKHLEIAREvSDRVGEGSAYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKHLEIA 400 555555555556666554223333477889999999999999999999999888888888888888899999999999999999999999999999 PP TPR_MalT 111 qesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql 155 +e + + g ++ l++ + +d+ +A ++ ++ +++++++ FUN_002345-T1 401 KEVSDRV--GEGSAYGNLGNTYQSLGDFRKAIEYHEKHLEIAKEV 443 9988885..777788888999999999999988888888888776 PP == domain 4 score: 16.6 bits; conditional E-value: 7.3e-06 TPR_MalT 11 avsqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqq 105 + s g++ +a+e+ ++ L++ +e +d ++a+ +lG a+ +g++ +A + +e ++a + ++ a+ ++++ +r G++++A+e ++ FUN_002345-T1 420 YQSLGDFRKAIEYHEKHLEIAKEvSDRVGEGSAYGSLGNAYKSLGNFRKAIEYHEERLEIAIEVGNRVGEGNAYGSLGNAYRSLGDFRKAIEYHEK 515 6678999*************98734444559999*********************************99*************************** PP TPR_MalT 106 alqlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiql 151 l+ a e++ + g ++ l++ + +d+ +A ++ q+ ++ FUN_002345-T1 516 CLEIAIEASHRV--GEGSAYGNLGNAFQSLGDFRKAIEYHQKHFEI 559 ******999885..77788889999999999999998888876655 PP == domain 5 score: 12.8 bits; conditional E-value: 0.00011 TPR_MalT 12 vsqgeaeeaeelAreALallpeddllar.tlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqa 106 s g++ +a+e+ ++ L++ e ++ + ++a+ +lG a++ +gd+ +A + ++ ++a + ++ a+ +++ ++ G++++A+e ++ FUN_002345-T1 501 RSLGDFRKAIEYHEKCLEIAIEASHRVGeGSAYGNLGNAFQSLGDFRKAIEYHQKHFEIAIEVGHRVGEGNAYGSLGIAYQSLGDFRKAIEYHEKH 596 57899********************9988*****************************999999999999***********************999 PP TPR_MalT 107 lqlaqe 112 l+ a e FUN_002345-T1 597 LEIAIE 602 999877 PP == domain 6 score: 11.7 bits; conditional E-value: 0.00023 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 s g++ +a+e+ ++ L++ +e +d + a+ +lG a++ +gd+ +A + ++ ++a + ++ ++ +++ ++ G++++A e ++ l FUN_002345-T1 622 SLGDFRKAIEYQEKRLEIAKEvSDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGHRVGEGSTYGNLGNAYQSLGDFQKAVEYHEKHL 717 56889999999999999998733444559999********************999999999999999999************************** PP TPR_MalT 108 qlaqes 113 + a+e FUN_002345-T1 718 EIAKEV 723 999985 PP == domain 7 score: 2.8 bits; conditional E-value: 0.12 TPR_MalT 40 tlatlvlGeasllqgdlesAlaalreaeal 69 ++a+ + Ge ++++g++e+Al+ + +a ++ FUN_002345-T1 730 GIAYHNVGEEYFCLGQFENALDNFVYAVEA 759 578899***************999888765 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.1 0.55 3.9e+02 5 22 .. 15 32 .. 13 34 .. 0.92 2 ? 4.0 0.1 0.2 1.4e+02 5 22 .. 95 112 .. 92 112 .. 0.92 3 ? 3.9 0.0 0.21 1.5e+02 6 25 .. 136 155 .. 135 159 .. 0.85 4 ? 2.4 0.0 0.61 4.3e+02 5 22 .. 175 192 .. 170 194 .. 0.77 5 ? 4.3 0.0 0.15 1.1e+02 6 25 .. 216 235 .. 215 239 .. 0.85 6 ? 3.5 0.0 0.28 2e+02 5 25 .. 255 275 .. 252 279 .. 0.85 7 ? 1.1 0.1 1.7 1.2e+03 5 22 .. 295 312 .. 291 314 .. 0.90 8 ? 4.2 0.0 0.17 1.2e+02 5 22 .. 335 352 .. 332 352 .. 0.92 9 ? 2.8 0.0 0.47 3.3e+02 6 22 .. 376 392 .. 375 394 .. 0.93 10 ? 2.6 0.0 0.55 3.9e+02 5 22 .. 415 432 .. 410 435 .. 0.75 11 ? 1.7 0.0 1 7.4e+02 6 22 .. 456 472 .. 455 472 .. 0.92 12 ? 4.3 0.0 0.15 1.1e+02 6 25 .. 496 515 .. 495 519 .. 0.85 13 ? 2.5 0.0 0.59 4.2e+02 5 22 .. 535 552 .. 530 555 .. 0.80 14 ? 2.9 0.0 0.43 3e+02 6 22 .. 576 592 .. 575 594 .. 0.93 15 ? 2.7 0.0 0.5 3.6e+02 6 22 .. 616 632 .. 615 632 .. 0.92 16 ? 3.6 0.0 0.26 1.8e+02 5 22 .. 655 672 .. 652 673 .. 0.92 17 ? 4.4 0.0 0.14 1e+02 6 22 .. 696 712 .. 695 714 .. 0.92 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.55 TPR_6 5 klalsylelgdkdeAkaa 22 +la++++ lg++ +A+++ FUN_002345-T1 15 NLAYAFQSLGNFRKAIKY 32 69*************986 PP == domain 2 score: 4.0 bits; conditional E-value: 0.2 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002345-T1 95 NLGNAYRSLGDFRKAIEY 112 59*************986 PP == domain 3 score: 3.9 bits; conditional E-value: 0.21 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd+ +A+++ ++ FUN_002345-T1 136 LGNAYQSLGDFRKAIEYHEK 155 799************98655 PP == domain 4 score: 2.4 bits; conditional E-value: 0.61 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ y+ lgd+ +A+++ FUN_002345-T1 175 NLGNTYQSLGDFRKAIEY 192 478888888888888875 PP == domain 5 score: 4.3 bits; conditional E-value: 0.15 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd+ +A+++ ++ FUN_002345-T1 216 LGNAYRSLGDFRKAIEYHEK 235 799************98655 PP == domain 6 score: 3.5 bits; conditional E-value: 0.28 TPR_6 5 klalsylelgdkdeAkaalqr 25 +l+ +y lgd+ +A+++ ++ FUN_002345-T1 255 NLGNAYWSLGDFRKAIEYHEK 275 599*************98655 PP == domain 7 score: 1.1 bits; conditional E-value: 1.7 TPR_6 5 klalsylelgdkdeAkaa 22 +l+++y+ + d+ +A+++ FUN_002345-T1 295 NLGVAYQSMADFRKAIQY 312 5899****99*****986 PP == domain 8 score: 4.2 bits; conditional E-value: 0.17 TPR_6 5 klalsylelgdkdeAkaa 22 +l+++y+ lgd+ +A+++ FUN_002345-T1 335 NLGVAYQSLGDFRKAIEY 352 59*************986 PP == domain 9 score: 2.8 bits; conditional E-value: 0.47 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002345-T1 376 LGNAYQSLGDFRKAIEY 392 799***********986 PP == domain 10 score: 2.6 bits; conditional E-value: 0.55 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ y+ lgd+ +A+++ FUN_002345-T1 415 NLGNTYQSLGDFRKAIEY 432 477888888888888775 PP == domain 11 score: 1.7 bits; conditional E-value: 1 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lg++ +A+++ FUN_002345-T1 456 LGNAYKSLGNFRKAIEY 472 799***********986 PP == domain 12 score: 4.3 bits; conditional E-value: 0.15 TPR_6 6 lalsylelgdkdeAkaalqr 25 l+ +y+ lgd+ +A+++ ++ FUN_002345-T1 496 LGNAYRSLGDFRKAIEYHEK 515 799************98655 PP == domain 13 score: 2.5 bits; conditional E-value: 0.59 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +++ lgd+ +A+++ FUN_002345-T1 535 NLGNAFQSLGDFRKAIEY 552 578888888999999876 PP == domain 14 score: 2.9 bits; conditional E-value: 0.43 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002345-T1 576 LGIAYQSLGDFRKAIEY 592 799***********986 PP == domain 15 score: 2.7 bits; conditional E-value: 0.5 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y lgd+ +A+++ FUN_002345-T1 616 LGIAYDSLGDFRKAIEY 632 89************986 PP == domain 16 score: 3.6 bits; conditional E-value: 0.26 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lgd+ +A+++ FUN_002345-T1 655 NLGNAYQSLGDFRKAIEY 672 599************986 PP == domain 17 score: 4.4 bits; conditional E-value: 0.14 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002345-T1 696 LGNAYQSLGDFQKAVEY 712 89************986 PP >> DBD_Tnp_Mut MuDR family transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 1.8 1.2e+03 9 22 .. 19 32 .. 16 37 .. 0.88 2 ? 0.2 0.0 1.2 8.3e+02 6 23 .. 56 73 .. 54 82 .. 0.83 3 ? 0.4 0.0 1.1 7.6e+02 6 23 .. 96 113 .. 93 125 .. 0.88 4 ? 0.7 0.0 0.84 5.9e+02 6 22 .. 136 152 .. 134 158 .. 0.88 5 ? 0.9 0.0 0.74 5.3e+02 6 22 .. 176 192 .. 174 196 .. 0.88 6 ? 0.1 0.0 1.3 9.2e+02 6 22 .. 216 232 .. 213 235 .. 0.87 7 ? -1.7 0.0 4.6 3.3e+03 6 22 .. 256 272 .. 255 274 .. 0.83 8 ? 1.0 0.0 0.69 4.9e+02 6 23 .. 296 313 .. 294 326 .. 0.87 9 ? 1.1 0.0 0.63 4.5e+02 6 23 .. 336 353 .. 334 366 .. 0.87 10 ? 0.9 0.0 0.74 5.3e+02 6 23 .. 376 393 .. 374 405 .. 0.88 11 ? 1.1 0.0 0.63 4.5e+02 6 23 .. 416 433 .. 414 445 .. 0.89 12 ? 0.8 0.0 0.77 5.4e+02 6 22 .. 456 472 .. 454 476 .. 0.89 13 ? 0.1 0.0 1.3 8.9e+02 6 22 .. 496 512 .. 493 516 .. 0.88 14 ? 4.6 0.0 0.05 35 6 23 .. 536 553 .. 533 562 .. 0.84 15 ? 1.1 0.0 0.65 4.6e+02 6 22 .. 576 592 .. 573 598 .. 0.89 16 ? 1.3 0.0 0.54 3.8e+02 6 21 .. 616 631 .. 612 641 .. 0.91 17 ? 2.5 0.0 0.23 1.6e+02 6 24 .. 656 674 .. 652 683 .. 0.89 18 ? -2.3 0.0 7.1 5.1e+03 6 22 .. 696 712 .. 695 714 .. 0.87 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 1.8 DBD_Tnp_Mut 9 kFkdleefrkAlrk 22 F++l +frkA++ FUN_002345-T1 19 AFQSLGNFRKAIKY 32 69*********986 PP == domain 2 score: 0.2 bits; conditional E-value: 1.2 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002345-T1 56 LGNAYQSLCDFRKAIEYH 73 68999*********9876 PP == domain 3 score: 0.4 bits; conditional E-value: 1.1 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G + +l +frkA++ + FUN_002345-T1 96 LGNAYRSLGDFRKAIEYH 113 689999********9865 PP == domain 4 score: 0.7 bits; conditional E-value: 0.84 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002345-T1 136 LGNAYQSLGDFRKAIEY 152 69999*********985 PP == domain 5 score: 0.9 bits; conditional E-value: 0.74 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002345-T1 176 LGNTYQSLGDFRKAIEY 192 6999**********986 PP == domain 6 score: 0.1 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002345-T1 216 LGNAYRSLGDFRKAIEY 232 68999*********985 PP == domain 7 score: -1.7 bits; conditional E-value: 4.6 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002345-T1 256 LGNAYWSLGDFRKAIEY 272 5778889*******975 PP == domain 8 score: 1.0 bits; conditional E-value: 0.69 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G ++++++frkA++ + FUN_002345-T1 296 LGVAYQSMADFRKAIQYH 313 69999*********9865 PP == domain 9 score: 1.1 bits; conditional E-value: 0.63 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002345-T1 336 LGVAYQSLGDFRKAIEYH 353 69999*********9865 PP == domain 10 score: 0.9 bits; conditional E-value: 0.74 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002345-T1 376 LGNAYQSLGDFRKAIEYH 393 69999*********9865 PP == domain 11 score: 1.1 bits; conditional E-value: 0.63 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G +++l +frkA++ + FUN_002345-T1 416 LGNTYQSLGDFRKAIEYH 433 6999**********9865 PP == domain 12 score: 0.8 bits; conditional E-value: 0.77 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +k+l +frkA++ FUN_002345-T1 456 LGNAYKSLGNFRKAIEY 472 6999**********986 PP == domain 13 score: 0.1 bits; conditional E-value: 1.3 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G + +l +frkA++ FUN_002345-T1 496 LGNAYRSLGDFRKAIEY 512 689999********985 PP == domain 14 score: 4.6 bits; conditional E-value: 0.05 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrky 23 +G F++l +frkA++ + FUN_002345-T1 536 LGNAFQSLGDFRKAIEYH 553 799************876 PP == domain 15 score: 1.1 bits; conditional E-value: 0.65 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +frkA++ FUN_002345-T1 576 LGIAYQSLGDFRKAIEY 592 7999**********986 PP == domain 16 score: 1.3 bits; conditional E-value: 0.54 DBD_Tnp_Mut 6 vGlkFkdleefrkAlr 21 +G +++l +frkA++ FUN_002345-T1 616 LGIAYDSLGDFRKAIE 631 7999**********96 PP == domain 17 score: 2.5 bits; conditional E-value: 0.23 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrkya 24 +G +++l +frkA++ +a FUN_002345-T1 656 LGNAYQSLGDFRKAIEYHA 674 79999**********9987 PP == domain 18 score: -2.3 bits; conditional E-value: 7.1 DBD_Tnp_Mut 6 vGlkFkdleefrkAlrk 22 +G +++l +f+kA++ FUN_002345-T1 696 LGNAYQSLGDFQKAVEY 712 68999*********975 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.0 7.8 5.6e+03 9 24 .. 19 34 .. 13 35 .. 0.78 2 ? 4.1 0.0 0.14 96 3 24 .. 93 114 .. 92 115 .. 0.88 3 ? 6.1 0.0 0.03 21 2 26 .. 132 156 .. 131 159 .. 0.90 4 ? 0.4 0.0 2 1.4e+03 3 25 .. 173 195 .. 171 195 .. 0.78 5 ? 6.8 0.0 0.018 13 3 26 .. 213 236 .. 212 239 .. 0.90 6 ? 5.8 0.1 0.038 27 2 26 .. 252 276 .. 251 279 .. 0.88 7 ? 0.3 0.0 2.1 1.5e+03 8 24 .. 338 354 .. 331 355 .. 0.78 8 ? 5.1 0.0 0.063 45 2 24 .. 372 394 .. 371 395 .. 0.91 9 ? -0.3 0.0 3.4 2.4e+03 3 24 .. 413 434 .. 411 435 .. 0.76 10 ? 7.3 0.1 0.013 9.2 2 25 .. 452 475 .. 451 475 .. 0.93 11 ? 6.8 0.0 0.018 13 3 26 .. 493 516 .. 492 519 .. 0.90 12 ? 1.0 0.0 1.3 9.3e+02 2 24 .. 532 554 .. 531 555 .. 0.85 13 ? 1.5 0.0 0.87 6.2e+02 3 24 .. 573 594 .. 572 595 .. 0.86 14 ? 1.4 0.0 0.95 6.7e+02 3 23 .. 653 673 .. 652 675 .. 0.86 15 ? 4.9 0.0 0.074 52 1 24 [. 691 714 .. 691 715 .. 0.92 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 7.8 PPR 9 gycknGkleeAlelfk 24 ++ + G++++A+++++ FUN_002345-T1 19 AFQSLGNFRKAIKYHE 34 66678*******9987 PP == domain 2 score: 4.1 bits; conditional E-value: 0.14 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002345-T1 93 YGNLGNAYRSLGDFRKAIEYHD 114 778889*************987 PP == domain 3 score: 6.1 bits; conditional E-value: 0.03 PPR 2 tynslIsgycknGkleeAlelfkeM 26 +y sl ++y + G++++A+e++++ FUN_002345-T1 132 AYGSLGNAYQSLGDFRKAIEYHEKC 156 799*****************99975 PP == domain 4 score: 0.4 bits; conditional E-value: 2 PPR 3 ynslIsgycknGkleeAlelfke 25 y l + y + G++++A+e+++e FUN_002345-T1 173 YGNLGNTYQSLGDFRKAIEYHEE 195 55555667789********9987 PP == domain 5 score: 6.8 bits; conditional E-value: 0.018 PPR 3 ynslIsgycknGkleeAlelfkeM 26 y sl ++y + G++++A+e++++ FUN_002345-T1 213 YGSLGNAYRSLGDFRKAIEYHEKC 236 99999**************99975 PP == domain 6 score: 5.8 bits; conditional E-value: 0.038 PPR 2 tynslIsgycknGkleeAlelfkeM 26 +y l ++y + G++++A+e++++ FUN_002345-T1 252 AYGNLGNAYWSLGDFRKAIEYHEKC 276 688899**************99975 PP == domain 7 score: 0.3 bits; conditional E-value: 2.1 PPR 8 sgycknGkleeAlelfk 24 +y + G++++A+e+++ FUN_002345-T1 338 VAYQSLGDFRKAIEYHD 354 588899********987 PP == domain 8 score: 5.1 bits; conditional E-value: 0.063 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002345-T1 372 AYGSLGNAYQSLGDFRKAIEYHE 394 799*****************987 PP == domain 9 score: -0.3 bits; conditional E-value: 3.4 PPR 3 ynslIsgycknGkleeAlelfk 24 y l + y + G++++A+e+++ FUN_002345-T1 413 YGNLGNTYQSLGDFRKAIEYHE 434 55555667789*******9987 PP == domain 10 score: 7.3 bits; conditional E-value: 0.013 PPR 2 tynslIsgycknGkleeAlelfke 25 +y sl ++y + G++++A+e+++e FUN_002345-T1 452 AYGSLGNAYKSLGNFRKAIEYHEE 475 799*****************9987 PP == domain 11 score: 6.8 bits; conditional E-value: 0.018 PPR 3 ynslIsgycknGkleeAlelfkeM 26 y sl ++y + G++++A+e++++ FUN_002345-T1 493 YGSLGNAYRSLGDFRKAIEYHEKC 516 99999**************99975 PP == domain 12 score: 1.0 bits; conditional E-value: 1.3 PPR 2 tynslIsgycknGkleeAlelfk 24 +y l +++ + G++++A+e+++ FUN_002345-T1 532 AYGNLGNAFQSLGDFRKAIEYHQ 554 57888899999********9876 PP == domain 13 score: 1.5 bits; conditional E-value: 0.87 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl +y + G++++A+e+++ FUN_002345-T1 573 YGSLGIAYQSLGDFRKAIEYHE 594 7788889999*********987 PP == domain 14 score: 1.4 bits; conditional E-value: 0.95 PPR 3 ynslIsgycknGkleeAlelf 23 y l ++y + G++++A+e++ FUN_002345-T1 653 YGNLGNAYQSLGDFRKAIEYH 673 777889************975 PP == domain 15 score: 4.9 bits; conditional E-value: 0.074 PPR 1 vtynslIsgycknGkleeAlelfk 24 +ty l ++y + G++++A+e+++ FUN_002345-T1 691 STYGNLGNAYQSLGDFQKAVEYHE 714 5999*****************987 PP >> DUF2977 Protein of unknown function (DUF2977) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 1.3 9.1e+02 13 31 .. 19 37 .. 13 41 .. 0.83 2 ? 0.7 0.0 1.1 8e+02 14 31 .. 100 117 .. 97 120 .. 0.88 3 ? 0.4 0.0 1.4 9.9e+02 14 30 .. 140 156 .. 138 159 .. 0.87 4 ? 1.7 0.0 0.57 4e+02 14 31 .. 180 197 .. 178 200 .. 0.89 5 ? 0.1 0.0 1.7 1.2e+03 14 31 .. 220 237 .. 219 240 .. 0.86 6 ? 0.2 0.0 1.6 1.2e+03 14 30 .. 260 276 .. 258 279 .. 0.86 7 ? -2.2 0.0 8.9 6.3e+03 12 31 .. 298 317 .. 295 319 .. 0.84 8 ? 2.9 0.0 0.24 1.7e+02 12 31 .. 338 357 .. 334 360 .. 0.88 9 ? 1.3 0.0 0.75 5.3e+02 14 31 .. 380 397 .. 378 400 .. 0.89 10 ? 1.2 0.0 0.79 5.6e+02 14 31 .. 420 437 .. 418 440 .. 0.88 11 ? 1.6 0.0 0.62 4.4e+02 14 31 .. 460 477 .. 458 480 .. 0.89 12 ? 0.2 0.0 1.7 1.2e+03 14 31 .. 500 517 .. 499 521 .. 0.86 13 ? 2.8 0.0 0.24 1.7e+02 12 31 .. 578 597 .. 576 600 .. 0.91 14 ? 0.8 0.0 1.1 7.8e+02 12 31 .. 618 637 .. 614 640 .. 0.87 15 ? -1.6 0.0 6.2 4.4e+03 14 30 .. 660 676 .. 658 679 .. 0.84 16 ? -1.8 0.0 6.9 4.9e+03 14 31 .. 700 717 .. 698 719 .. 0.88 17 ? 0.2 0.0 1.7 1.2e+03 14 25 .. 740 751 .. 738 769 .. 0.84 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 1.3 DUF2977 13 sYvlvGgledgidvdednl 31 + G ++++i ++e+ l FUN_002345-T1 19 AFQSLGNFRKAIKYHEKHL 37 67789***********987 PP == domain 2 score: 0.7 bits; conditional E-value: 1.1 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++++ l FUN_002345-T1 100 YRSLGDFRKAIEYHDKHL 117 7789**********9877 PP == domain 3 score: 0.4 bits; conditional E-value: 1.4 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++e+ FUN_002345-T1 140 YQSLGDFRKAIEYHEKC 156 7889**********976 PP == domain 4 score: 1.7 bits; conditional E-value: 0.57 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002345-T1 180 YQSLGDFRKAIEYHEERL 197 7789***********987 PP == domain 5 score: 0.1 bits; conditional E-value: 1.7 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002345-T1 220 YRSLGDFRKAIEYHEKCL 237 7789**********9865 PP == domain 6 score: 0.2 bits; conditional E-value: 1.6 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++e+ FUN_002345-T1 260 YWSLGDFRKAIEYHEKC 276 7789**********976 PP == domain 7 score: -2.2 bits; conditional E-value: 8.9 DUF2977 12 isYvlvGgledgidvdednl 31 + Y + ++++i ++++ l FUN_002345-T1 298 VAYQSMADFRKAIQYHDKHL 317 678888999*******9876 PP == domain 8 score: 2.9 bits; conditional E-value: 0.24 DUF2977 12 isYvlvGgledgidvdednl 31 + Y G ++++i+++++ l FUN_002345-T1 338 VAYQSLGDFRKAIEYHDKHL 357 78999***********9877 PP == domain 9 score: 1.3 bits; conditional E-value: 0.75 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002345-T1 380 YQSLGDFRKAIEYHEKHL 397 7889***********987 PP == domain 10 score: 1.2 bits; conditional E-value: 0.79 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002345-T1 420 YQSLGDFRKAIEYHEKHL 437 7789***********987 PP == domain 11 score: 1.6 bits; conditional E-value: 0.62 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002345-T1 460 YKSLGNFRKAIEYHEERL 477 7789***********987 PP == domain 12 score: 0.2 bits; conditional E-value: 1.7 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++i+++e+ l FUN_002345-T1 500 YRSLGDFRKAIEYHEKCL 517 7789**********9865 PP == domain 13 score: 2.8 bits; conditional E-value: 0.24 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002345-T1 578 IAYQSLGDFRKAIEYHEKHL 597 78999************987 PP == domain 14 score: 0.8 bits; conditional E-value: 1.1 DUF2977 12 isYvlvGgledgidvdednl 31 i Y G ++++i+++e+ l FUN_002345-T1 618 IAYDSLGDFRKAIEYQEKRL 637 88999***********9877 PP == domain 15 score: -1.6 bits; conditional E-value: 6.2 DUF2977 14 YvlvGgledgidvdedn 30 Y G ++++i+++ + FUN_002345-T1 660 YQSLGDFRKAIEYHAKH 676 7789*********9765 PP == domain 16 score: -1.8 bits; conditional E-value: 6.9 DUF2977 14 YvlvGgledgidvdednl 31 Y G ++++++++e+ l FUN_002345-T1 700 YQSLGDFQKAVEYHEKHL 717 7789**********9876 PP == domain 17 score: 0.2 bits; conditional E-value: 1.7 DUF2977 14 YvlvGgledgid 25 Y G++e+++d FUN_002345-T1 740 YFCLGQFENALD 751 7789*******9 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 2 1.4e+03 3 19 .. 16 32 .. 15 74 .. 0.73 2 ? 6.6 0.1 0.021 15 19 59 .. 76 118 .. 47 122 .. 0.77 3 ? 1.9 0.0 0.63 4.5e+02 3 19 .. 136 152 .. 135 157 .. 0.91 4 ? 6.6 0.1 0.022 16 3 53 .. 176 232 .. 175 232 .. 0.80 5 ! 13.7 0.1 0.00013 0.091 3 53 .. 216 272 .. 215 281 .. 0.88 6 ? 2.6 0.1 0.38 2.7e+02 30 59 .. 329 358 .. 295 362 .. 0.75 7 ? 2.0 0.0 0.59 4.2e+02 3 19 .. 376 392 .. 371 400 .. 0.89 8 ? 0.7 0.0 1.5 1.1e+03 3 19 .. 416 432 .. 408 441 .. 0.82 9 ? 6.8 0.1 0.019 13 3 53 .. 456 512 .. 455 518 .. 0.81 10 ? 7.1 0.1 0.015 11 3 53 .. 496 552 .. 495 560 .. 0.84 11 ? 4.8 0.0 0.08 57 3 57 .. 536 596 .. 535 601 .. 0.76 12 ? 7.2 0.1 0.014 9.8 3 55 .. 576 634 .. 575 641 .. 0.85 13 ? 4.3 0.2 0.11 78 3 53 .. 656 712 .. 650 721 .. 0.66 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 2 TPR_16 3 laraalaagdyddAaaa 19 la a+ +g+++ A+++ FUN_002345-T1 16 LAYAFQSLGNFRKAIKY 32 78899999999999875 PP == domain 2 score: 6.6 bits; conditional E-value: 0.021 TPR_16 19 aleaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalr 59 +e a++ + A+ +lG a+ +g++ +A+++ ++ l+ FUN_002345-T1 76 HFEIAIEVGhrVGEGNAYGNLGNAYRSLGDFRKAIEYHDKHLE 118 5777777777755788999999999999999999998777765 PP == domain 3 score: 1.9 bits; conditional E-value: 0.63 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002345-T1 136 LGNAYQSLGDFRKAIEY 152 799***********986 PP == domain 4 score: 6.6 bits; conditional E-value: 0.022 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++ + +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ FUN_002345-T1 176 LGNTYQSLGDFRKAIEYheerLEIAIEVGnrVGEGNAYGSLGNAYRSLGDFRKAIEY 232 788899999999998643333888888889977899999999999999999999875 PP == domain 5 score: 13.7 bits; conditional E-value: 0.00013 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a++ +gd++ A+++ le a++++ A+ +lG a++ +g++ +A+++ FUN_002345-T1 216 LGNAYRSLGDFRKAIEYhekcLEIAIEAGhrVGEGSAYGNLGNAYWSLGDFRKAIEY 272 799***********8744444999*******77999******************987 PP == domain 6 score: 2.6 bits; conditional E-value: 0.38 TPR_16 30 aaaAllglGlallrqgrlaeAaaayraalr 59 A+ +lG+a+ +g++ +A+++ ++ l+ FUN_002345-T1 329 EGSAYGNLGVAYQSLGDFRKAIEYHDKHLE 358 567888899999899999888888777665 PP == domain 7 score: 2.0 bits; conditional E-value: 0.59 TPR_16 3 laraalaagdyddAaaa 19 l++a+ +gd++ A+++ FUN_002345-T1 376 LGNAYQSLGDFRKAIEY 392 79999999999999986 PP == domain 8 score: 0.7 bits; conditional E-value: 1.5 TPR_16 3 laraalaagdyddAaaa 19 l++ + +gd++ A+++ FUN_002345-T1 416 LGNTYQSLGDFRKAIEY 432 68888888888888875 PP == domain 9 score: 6.8 bits; conditional E-value: 0.019 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +g+++ A+++ le a++ + A+ lG a+ +g++ +A+++ FUN_002345-T1 456 LGNAYKSLGNFRKAIEYheerLEIAIEVGnrVGEGNAYGSLGNAYRSLGDFRKAIEY 512 688899999999997643333888888889967899999999999999999999976 PP == domain 10 score: 7.1 bits; conditional E-value: 0.015 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a++ +gd++ A+++ le a+++ A+ +lG a+ +g++ +A+++ FUN_002345-T1 496 LGNAYRSLGDFRKAIEYhekcLEIAIEAShrVGEGSAYGNLGNAFQSLGDFRKAIEY 552 7999**********8743333889999999966899999999999999999999987 PP == domain 11 score: 4.8 bits; conditional E-value: 0.08 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraa 57 l++a+ +gd++ A+++ +e a++ + A+ lG a+ +g++ +A+++ ++ FUN_002345-T1 536 LGNAFQSLGDFRKAIEYhqkhFEIAIEVGhrVGEGNAYGSLGIAYQSLGDFRKAIEYHEKH 596 7899999999999986444448888888888667888888888888888888888876555 PP == domain 12 score: 7.2 bits; conditional E-value: 0.014 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayr 55 l+ a+ +gd++ A+++ le a++ + A+ +lG a+ +g++ +A+++ + FUN_002345-T1 576 LGIAYQSLGDFRKAIEYhekhLEIAIEVGnrVGEGNAYGNLGIAYDSLGDFRKAIEYQE 634 688999999999998754444999999999977999*******************8866 PP == domain 13 score: 4.3 bits; conditional E-value: 0.11 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++a+ +gd++ A+++ le a++ + + +lG a+ +g++++A+++ FUN_002345-T1 656 LGNAYQSLGDFRKAIEYhakhLEIAIEVGhrVGEGSTYGNLGNAYQSLGDFQKAVEY 712 688888888888887543333666666666644566666777777777777777666 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.1 0.22 1.6e+02 37 73 .. 11 47 .. 8 48 .. 0.92 2 ? 2.3 0.0 0.23 1.6e+02 38 72 .. 52 86 .. 50 88 .. 0.91 3 ? 1.1 0.0 0.54 3.8e+02 38 64 .. 92 118 .. 90 127 .. 0.87 4 ? 3.8 0.2 0.081 58 37 65 .. 131 159 .. 107 167 .. 0.79 5 ? 2.8 0.0 0.16 1.1e+02 38 70 .. 172 204 .. 169 208 .. 0.85 6 ? 6.4 0.0 0.013 9.2 38 73 .. 212 247 .. 210 248 .. 0.92 7 ? 5.8 0.1 0.019 14 38 70 .. 252 284 .. 250 327 .. 0.85 8 ? 0.2 0.1 1.1 7.5e+02 37 64 .. 331 358 .. 304 367 .. 0.83 9 ? 2.1 0.2 0.27 1.9e+02 37 64 .. 371 398 .. 347 407 .. 0.78 10 ? 3.4 0.3 0.11 79 37 64 .. 411 438 .. 388 448 .. 0.80 11 ? -0.7 0.0 2 1.4e+03 38 69 .. 452 483 .. 449 488 .. 0.83 12 ? 5.4 0.1 0.026 18 38 72 .. 492 526 .. 467 528 .. 0.90 13 ? 4.8 0.1 0.039 28 38 104 .. 532 598 .. 530 632 .. 0.72 14 ! 7.7 1.0 0.0051 3.6 30 144 .. 644 761 .. 624 771 .. 0.68 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.22 RPN7 37 raledlaehyakigdlenAlkayerarekttslghki 73 +++++la + + g++++A+k+ e+ +e ++ +gh + FUN_002345-T1 11 KGYQNLAYAFQSLGNFRKAIKYHEKHLEIAIEAGHRV 47 678999**********************999999975 PP == domain 2 score: 2.3 bits; conditional E-value: 0.23 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ +l++ y + +d+++A+++ ++ +e ++ gh FUN_002345-T1 52 AYGNLGNAYQSLCDFRKAIEYHQKHFEIAIEVGHR 86 6889*********************9999999987 PP == domain 3 score: 1.1 bits; conditional E-value: 0.54 RPN7 38 aledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ + +e FUN_002345-T1 92 AYGNLGNAYRSLGDFRKAIEYHDKHLE 118 7889****************9988766 PP == domain 4 score: 3.8 bits; conditional E-value: 0.081 RPN7 37 raledlaehyakigdlenAlkayerarek 65 a+ l++ y + gd+++A+++ e+++e FUN_002345-T1 131 SAYGSLGNAYQSLGDFRKAIEYHEKCLEI 159 678899*******************9985 PP == domain 5 score: 2.8 bits; conditional E-value: 0.16 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ +l++ y + gd+++A+++ e+ +e ++ g FUN_002345-T1 172 AYGNLGNTYQSLGDFRKAIEYHEERLEIAIEVG 204 6889******************99888766655 PP == domain 6 score: 6.4 bits; conditional E-value: 0.013 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ l++ y + gd+++A+++ e+++e ++ +gh + FUN_002345-T1 212 AYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEAGHRV 247 677899***********************9999975 PP == domain 7 score: 5.8 bits; conditional E-value: 0.019 RPN7 38 aledlaehyakigdlenAlkayerarekttslg 70 a+ +l++ y + gd+++A+++ e+++e +t + FUN_002345-T1 252 AYGNLGNAYWSLGDFRKAIEYHEKCLEIATEVS 284 6889*********************99888765 PP == domain 8 score: 0.2 bits; conditional E-value: 1.1 RPN7 37 raledlaehyakigdlenAlkayerare 64 a+ +l+ y + gd+++A+++ + +e FUN_002345-T1 331 SAYGNLGVAYQSLGDFRKAIEYHDKHLE 358 578899999************9988766 PP == domain 9 score: 2.1 bits; conditional E-value: 0.27 RPN7 37 raledlaehyakigdlenAlkayerare 64 a+ l++ y + gd+++A+++ e+ +e FUN_002345-T1 371 SAYGSLGNAYQSLGDFRKAIEYHEKHLE 398 678899****************999876 PP == domain 10 score: 3.4 bits; conditional E-value: 0.11 RPN7 37 raledlaehyakigdlenAlkayerare 64 a+ +l++ y + gd+++A+++ e+ +e FUN_002345-T1 411 SAYGNLGNTYQSLGDFRKAIEYHEKHLE 438 68999******************99876 PP == domain 11 score: -0.7 bits; conditional E-value: 2 RPN7 38 aledlaehyakigdlenAlkayerarekttsl 69 a+ l++ y + g++++A+++ e+ +e ++ FUN_002345-T1 452 AYGSLGNAYKSLGNFRKAIEYHEERLEIAIEV 483 67789999*************99988766665 PP == domain 12 score: 5.4 bits; conditional E-value: 0.026 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ l++ y + gd+++A+++ e+++e ++ ++h FUN_002345-T1 492 AYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEASHR 526 77889**********************99998886 PP == domain 13 score: 4.8 bits; conditional E-value: 0.039 RPN7 38 aledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiffndwalvskylekakslie 104 a+ +l++ + + gd+++A+++ ++ +e ++ gh + + +gi+++ + k +e ++ +e FUN_002345-T1 532 AYGNLGNAFQSLGDFRKAIEYHQKHFEIAIEVGHRVGEGNAYGSLGIAYQSLGDFRKAIEYHEKHLE 598 6788999999999999999999999999999999987777777777777766666666666555555 PP == domain 14 score: 7.7 bits; conditional E-value: 0.0051 RPN7 30 lgkeeirraledlaehyakigdlenAlkayerarekttslghkidlllnlirvgiff...ndwalvskylekaksliekggdwerrnrlkvyeGla 122 + +a+ +l++ y + gd+++A+++ ++ +e ++ gh + + ++g ++ +d++++ +y ek ++ ++ gd+ + G FUN_002345-T1 644 SDRVGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGHRVGEGSTYGNLGNAYqslGDFQKAVEYHEKHLEIAKEVGDRAGEGIAYHNVGEE 739 555555578999*****************************9986555555555544111566666666666666677777766666666666666 PP RPN7 123 alairkfkeAakllldslstft 144 +++ ++f+ A ++++ ++ f FUN_002345-T1 740 YFCLGQFENALDNFVYAVEAFN 761 7777777777777777766665 PP >> TPR_NPHP3 Nephrocystin-3 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 3.1 2.2e+03 146 171 .. 15 40 .. 9 79 .. 0.74 2 ? 6.0 0.0 0.013 9.4 100 173 .. 91 162 .. 67 166 .. 0.84 3 ? 5.6 0.0 0.018 13 100 170 .. 131 199 .. 107 209 .. 0.69 4 ? 6.0 0.0 0.014 9.8 100 214 .. 211 321 .. 188 331 .. 0.77 5 ? 4.3 0.1 0.043 31 100 172 .. 331 401 .. 295 409 .. 0.68 6 ? 6.3 0.1 0.011 7.5 99 172 .. 370 441 .. 340 444 .. 0.70 7 ? 5.5 0.0 0.019 14 84 170 .. 402 479 .. 388 489 .. 0.58 8 ? 3.3 0.0 0.089 63 76 128 .. 434 483 .. 426 524 .. 0.62 9 ? 2.1 0.0 0.21 1.5e+02 100 170 .. 491 559 .. 475 600 .. 0.69 10 ? 3.1 0.0 0.11 76 79 169 .. 637 718 .. 620 720 .. 0.57 11 ? 4.3 0.0 0.046 32 75 121 .. 713 759 .. 691 764 .. 0.58 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 3.1 TPR_NPHP3 146 qLagLyaqwgkfstaealykqaleiy 171 +La ++ g+f++a +++++ lei FUN_002345-T1 15 NLAYAFQSLGNFRKAIKYHEKHLEIA 40 56666666777777777777766664 PP == domain 2 score: 6.0 bits; conditional E-value: 0.013 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiyen 173 + y lG+ + lg +a++ ++ Lei + D ++++ L + y+ g f++a +++++ lei ++ FUN_002345-T1 91 NAYGNLGNAYRSLGDFRKAIEYHDKHLEIAKEV--SDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKE 162 678899999999999999999999999998877..566777888899999999999999999999999999765 PP == domain 3 score: 5.6 bits; conditional E-value: 0.018 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 + y +lG+ + lg +a++ ++ Lei + D ++++ +L + y+ g f++a +++++ lei FUN_002345-T1 131 SAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKEV--SDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEERLEI 199 456677777777777777777777888887666..456666777788888888888888888888887777 PP == domain 4 score: 6.0 bits; conditional E-value: 0.014 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlv.arslhqLagLyaqwgkfstaealykqaleiyenayGsdhelvakelealallyq 194 + y +lG+ + lg +a++ ++ Lei a++ h + ++++ +L + y g f++a +++++ lei + sd + + l + yq FUN_002345-T1 211 NAYGSLGNAYRSLGDFRKAIEYHEKCLEI---AIEAGHRVGeGSAYGNLGNAYWSLGDFRKAIEYHEKCLEIATEV--SDQVGEGSAYGNLGVAYQ 301 67999999999**********99**9998...56668877525567799999*99***************998776..455555566677777777 PP TPR_NPHP3 195 kqdkhdlaeplkkravairk 214 + + a + + + + i + FUN_002345-T1 302 SMADFRKAIQYHDKHLEIAR 321 77777777777777776665 PP == domain 5 score: 4.3 bits; conditional E-value: 0.043 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 + y lG + lg +a++ ++ Lei + D ++++ L + y+ g f++a +++++ lei + FUN_002345-T1 331 SAYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEV--SDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKHLEIAK 401 456666666667777777777777777776665..45555566777777777777777777777777777765 PP == domain 6 score: 6.3 bits; conditional E-value: 0.011 TPR_NPHP3 99 adlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqaleiye 172 + y +lG+ + lg +a++ ++ Lei + D ++++ +L + y+ g f++a +++++ lei + FUN_002345-T1 370 GSAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEKHLEIAK 441 3456777777777777777777777888887666..45666677888888888888888888888888888876 PP == domain 7 score: 5.5 bits; conditional E-value: 0.019 TPR_NPHP3 84 kledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqalei 170 ++ d v++ + y lG+ + lg +a++ ++ Lei + D ++++ L + y g+f++a +++++ lei FUN_002345-T1 402 EVSDRVGEGSA-------YGNLGNTYQSLGDFRKAIEYHEKHLEIAKEV--SDRVGEGSAYGSLGNAYKSLGNFRKAIEYHEERLEI 479 44444444444.......4444444444444455555556666665555..344455666667777777777777777777776666 PP == domain 8 score: 3.3 bits; conditional E-value: 0.089 TPR_NPHP3 76 kaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLei 128 +++l+ +k++ d v++ + ++ + y++lG+f k + + L+ a+e+ FUN_002345-T1 434 EKHLEIAKEVSDRVGEGSAYGSLGNAYKSLGNFRKAIEYHEE---RLEIAIEV 483 566777888888888888888888888888888887765443...34444444 PP == domain 9 score: 2.1 bits; conditional E-value: 0.21 TPR_NPHP3 100 dlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlv.arslhqLagLyaqwgkfstaealykqalei 170 + y +lG+ + lg +a++ ++ Lei a++ h + ++++ +L + ++ g f++a +++++ +ei FUN_002345-T1 491 NAYGSLGNAYRSLGDFRKAIEYHEKCLEI---AIEASHRVGeGSAYGNLGNAFQSLGDFRKAIEYHQKHFEI 559 56777888888888888888888888877...3444555531344556777777777777777777666655 PP == domain 10 score: 3.1 bits; conditional E-value: 0.11 TPR_NPHP3 79 lnaikkledavegeltlakvadlyealGrflkdlgllsqalpaLqraLeiRetaldPDhPlvarslhqLagLyaqwgkfstaealykqale 169 l+ +k++ d v++ + ++ + y++lG f k + ++ L+ a+e+ + ++++ +L + y+ g f++a +++++ le FUN_002345-T1 637 LEIAKEVSDRVGEGNAYGNLGNAYQSLGDFRKAIEYH---AKHLEIAIEVGHRV------GEGSTYGNLGNAYQSLGDFQKAVEYHEKHLE 718 5666667777766666777777777777776665432...33344444443332......1234455556666666666666665555555 PP == domain 11 score: 4.3 bits; conditional E-value: 0.046 TPR_NPHP3 75 akaYlnaikkledavegeltlakvadlyealGrflkdlgllsqalpa 121 +++l+ +k++ d +++ + ++v + y +lG+f + l a++a FUN_002345-T1 713 HEKHLEIAKEVGDRAGEGIAYHNVGEEYFCLGQFENALDNFVYAVEA 759 34556666666666666666666666666666666666665555554 PP >> WH_Halo_primase Halobacteria primase winged helix domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.4 1e+03 24 69 .. 59 107 .. 33 121 .. 0.74 2 ? 5.1 0.0 0.051 36 25 70 .. 100 148 .. 94 159 .. 0.84 3 ? 4.7 0.0 0.068 48 24 70 .. 139 188 .. 135 198 .. 0.81 4 ? 4.0 0.0 0.11 78 24 70 .. 179 228 .. 170 238 .. 0.81 5 ? 0.6 0.0 1.2 8.8e+02 26 69 .. 261 307 .. 256 321 .. 0.71 6 ? 0.9 0.0 1 7.3e+02 25 62 .. 300 337 .. 294 350 .. 0.79 7 ? 5.3 0.0 0.042 30 26 70 .. 341 388 .. 335 398 .. 0.85 8 ? 5.8 0.0 0.029 21 24 70 .. 379 428 .. 376 434 .. 0.82 9 ? 5.5 0.0 0.036 26 24 66 .. 419 464 .. 414 475 .. 0.83 10 ? 1.2 0.0 0.83 5.9e+02 27 70 .. 462 508 .. 456 516 .. 0.76 11 ? -0.7 0.0 3.1 2.2e+03 23 48 .. 538 563 .. 531 589 .. 0.75 12 ? 0.4 0.0 1.5 1e+03 30 60 .. 585 615 .. 575 678 .. 0.56 13 ? 0.9 0.0 1 7.4e+02 24 68 .. 659 706 .. 655 721 .. 0.79 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.4 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhr 69 + +s + ++A+e +++ e +v ++ + +Lgn +++ d r FUN_002345-T1 59 AYQSLCDFRKAIEYHQKHFEIAIEVGHRVGEgnaYGNLGNAYRSLGDFR 107 5678889999999999988888888888855333445555555555544 PP == domain 2 score: 5.1 bits; conditional E-value: 0.051 WH_Halo_primase 25 fhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 s + ++A+e +++ e ++v +++ s sLgn +++ d r+ FUN_002345-T1 100 YRSLGDFRKAIEYHDKHLEIAKEVSDRVgegSAYGSLGNAYQSLGDFRK 148 5677899*********************77666789***9999888776 PP == domain 3 score: 4.7 bits; conditional E-value: 0.068 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + +s + ++A+e +e+ e ++v +++ s +Lgn++++ d r+ FUN_002345-T1 139 AYQSLGDFRKAIEYHEKCLEIAKEVSDRVgegSAYGNLGNTYQSLGDFRK 188 6788999**********************665556789999988887776 PP == domain 4 score: 4.0 bits; conditional E-value: 0.11 WH_Halo_primase 24 efhsarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 + +s + ++A+e +e+ e +v n++ + sLgn +++ d r+ FUN_002345-T1 179 TYQSLGDFRKAIEYHEERLEIAIEVGNRVGEgnaYGSLGNAYRSLGDFRK 228 568899***********************553336789998888777665 PP == domain 5 score: 0.6 bits; conditional E-value: 1.2 WH_Halo_primase 26 hsarelydAleaYepereweqkvkneisspr...sLgnvLkkardhr 69 s + ++A+e +e+ e +v +++ + + +Lg +++ d r FUN_002345-T1 261 WSLGDFRKAIEYHEKCLEIATEVSDQVGEGSaygNLGVAYQSMADFR 307 56779999******999999999999966550014555555555544 PP == domain 6 score: 0.9 bits; conditional E-value: 1 WH_Halo_primase 25 fhsarelydAleaYepereweqkvkneissprsLgnvL 62 +s + ++A++ +++ e ++v +++ + ++ gn+ FUN_002345-T1 300 YQSMADFRKAIQYHDKHLEIAREVSDRVGEGSAYGNLG 337 57899***********************7766666654 PP == domain 7 score: 5.3 bits; conditional E-value: 0.042 WH_Halo_primase 26 hsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 +s + ++A+e +++ e ++v +++ s sLgn +++ d r+ FUN_002345-T1 341 QSLGDFRKAIEYHDKHLEIAKEVSDRVgegSAYGSLGNAYQSLGDFRK 388 678899*********************77666789****999888776 PP == domain 8 score: 5.8 bits; conditional E-value: 0.029 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardhrs 70 + +s + ++A+e +e+ e ++v +++ s +Lgn++++ d r+ FUN_002345-T1 379 AYQSLGDFRKAIEYHEKHLEIAKEVSDRVgegSAYGNLGNTYQSLGDFRK 428 5788999**********************665556788888888777665 PP == domain 9 score: 5.5 bits; conditional E-value: 0.036 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkar 66 + +s + ++A+e +e+ e ++v +++ s sLgn +k+ FUN_002345-T1 419 TYQSLGDFRKAIEYHEKHLEIAKEVSDRVgegSAYGSLGNAYKSLG 464 568899***********************77556789999998765 PP == domain 10 score: 1.2 bits; conditional E-value: 0.83 WH_Halo_primase 27 sarelydAleaYepereweqkvkneiss...prsLgnvLkkardhrs 70 s + ++A+e +e+ e +v n++ + sLgn +++ d r+ FUN_002345-T1 462 SLGNFRKAIEYHEERLEIAIEVGNRVGEgnaYGSLGNAYRSLGDFRK 508 56678999**9999999999999999553336788888888777665 PP == domain 11 score: -0.7 bits; conditional E-value: 3.1 WH_Halo_primase 23 gefhsarelydAleaYepereweqkv 48 ++f+s + ++A+e +++ e +v FUN_002345-T1 538 NAFQSLGDFRKAIEYHQKHFEIAIEV 563 6799999*******998876655555 PP == domain 12 score: 0.4 bits; conditional E-value: 1.5 WH_Halo_primase 30 elydAleaYepereweqkvkneissprsLgn 60 + ++A+e +e+ e +v n++ + + gn FUN_002345-T1 585 DFRKAIEYHEKHLEIAIEVGNRVGEGNAYGN 615 5556666665555555555555543332222 PP == domain 13 score: 0.9 bits; conditional E-value: 1 WH_Halo_primase 24 efhsarelydAleaYepereweqkvknei...ssprsLgnvLkkardh 68 + +s + ++A+e +++ e +v ++ s+ +Lgn +++ d FUN_002345-T1 659 AYQSLGDFRKAIEYHAKHLEIAIEVGHRVgegSTYGNLGNAYQSLGDF 706 567888999999999999999999999997767777888888876664 PP >> SNAP Soluble NSF attachment protein, SNAP # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.4 0.6 0.00031 0.22 38 181 .. 13 156 .. 9 167 .. 0.93 2 ! 14.9 0.0 2.8e-05 0.02 41 181 .. 136 276 .. 124 284 .. 0.90 3 ! 11.7 0.1 0.00026 0.18 42 176 .. 177 311 .. 171 326 .. 0.80 4 ? 2.4 0.6 0.18 1.3e+02 51 180 .. 306 435 .. 292 445 .. 0.62 5 ? 4.4 0.3 0.044 31 50 179 .. 345 474 .. 330 483 .. 0.65 6 ! 12.7 0.3 0.00013 0.093 42 179 .. 417 554 .. 410 560 .. 0.73 7 ! 12.5 0.1 0.00015 0.1 40 179 .. 455 594 .. 444 608 .. 0.81 8 ! 9.3 0.1 0.0014 0.96 38 144 .. 493 599 .. 486 641 .. 0.86 9 ! 6.5 0.2 0.0098 6.9 38 146 .. 653 761 .. 633 765 .. 0.74 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00031 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y++ A a++ ++++A + ++k e+ +++ + ++ay + ++y++ d +A+e +k +ei +e g ++ + ++++ y++ +d++ FUN_002345-T1 13 YQNLAYAFQSLGNFRKAIKYHEKHLEIAIEAGHRVGEGSAYGNLGNAYQSLcDFRKAIEYHQKHFEIAIEVGHRVGEGNAYGNLGNAYRSL-GDFR 107 677788999999************************************997799***********************************87.**** PP SNAP 133 kAieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyekv 181 kAie+ ++ ++ ++ + +++ + + + +l+++ kAie ek FUN_002345-T1 108 KAIEYHDKHLEIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKC 156 ***********99999999999999999999999999999999999974 PP == domain 2 score: 14.9 bits; conditional E-value: 2.8e-05 SNAP 41 AAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAi 135 +nay+ ++++A e ++k+ e+ ++++++ ++ay + + y++ d +A+e e+ ei +e g+ ++ + ++++ y++ +d++kAi FUN_002345-T1 136 LGNAYQSLGDFRKAIEYHEKCLEIAKEVSDRVGEGSAYGNLGNTYQSLgDFRKAIEYHEERLEIAIEVGNRVGEGNAYGSLGNAYRSL-GDFRKAI 230 5799999999999****************************99999977999*****************9999999*********987.******* PP SNAP 136 eaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiyekv 181 e+ e+ ++ + + +++ ++ + + +l+++ kAie ek FUN_002345-T1 231 EYHEKCLEIAIEAGHRVGEGSAYGNLGNAYWSLGDFRKAIEYHEKC 276 *****99999999999999999999999999999999999998875 PP == domain 3 score: 11.7 bits; conditional E-value: 0.00026 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +n y+ ++++A e +++ e+ +++++ +nay ++y++ d +A+e ek+ ei +e+g ++ + ++++ y + +d++kAie FUN_002345-T1 177 GNTYQSLGDFRKAIEYHEERLEIAIEVGNRVGEGNAYGSLGNAYRSLgDFRKAIEYHEKCLEIAIEAGHRVGEGSAYGNLGNAYWSL-GDFRKAIE 271 688888889999999999999999999999999999999999999877999999999999999999999999999999999999977.99999999 PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAie 176 + e+ ++ ++ + + +++ ++ + +++++ kAi+ FUN_002345-T1 272 YHEKCLEIATEVSDQVGEGSAYGNLGVAYQSMADFRKAIQ 311 9999888766665555555555555555555556666665 PP == domain 4 score: 2.4 bits; conditional E-value: 0.18 SNAP 51 wkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadly 145 +++A + + k e+ ++++++ ++ay + +y++ d +A+e +k ei e ++ + ++++ y++ +d++kAie+ e+ ++ FUN_002345-T1 306 FRKAIQYHDKHLEIAREVSDRVGEGSAYGNLGVAYQSLgDFRKAIEYHDKHLEIAKEVSDRVGEGSAYGSLGNAYQSL-GDFRKAIEYHEKHLEIA 400 555555555555555555555555666666555555544566666666666666555433333334455677777765.77777777777777777 PP SNAP 146 eqeeaealankcllkvAdlsaelekyekAieiyek 180 ++ + +++ ++ + + +l+++ kAie ek FUN_002345-T1 401 KEVSDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEK 435 77777777777777777777777777777776664 PP == domain 5 score: 4.4 bits; conditional E-value: 0.044 SNAP 50 kwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAieaYeqAadl 144 ++++A e + k e+ ++++++ ++ay ++y++ d +A+e ek ei e ++ + ++++ y++ +d++kAie+ e+ ++ FUN_002345-T1 345 DFRKAIEYHDKHLEIAKEVSDRVGEGSAYGSLGNAYQSLgDFRKAIEYHEKHLEIAKEVSDRVGEGSAYGNLGNTYQSL-GDFRKAIEYHEKHLEI 439 5566666666666666666666666666766667776655667777777777777666443334444556777777765.7777777777777777 PP SNAP 145 yeqeeaealankcllkvAdlsaelekyekAieiye 179 ++ + +++ + + + +l+++ kAie e FUN_002345-T1 440 AKEVSDRVGEGSAYGSLGNAYKSLGNFRKAIEYHE 474 66666666666677777777777777777776665 PP == domain 6 score: 12.7 bits; conditional E-value: 0.00013 SNAP 42 AnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekAie 136 +n y+ ++++A e ++k e+ ++++++ ++ay ++yk+ + +A+e e+ ei +e g+ ++ + ++++ y++ +d++kAie FUN_002345-T1 417 GNTYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEGSAYGSLGNAYKSLgNFRKAIEYHEERLEIAIEVGNRVGEGNAYGSLGNAYRSL-GDFRKAIE 511 577777777788888888888888888888888888888888888765777888888888888888888888888888888888866.88888888 PP SNAP 137 aYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiye 179 + e+ ++ + + +++ ++ + +l+++ kAie + FUN_002345-T1 512 YHEKCLEIAIEASHRVGEGSAYGNLGNAFQSLGDFRKAIEYHQ 554 8888777777666666677777777777777777777776554 PP == domain 7 score: 12.5 bits; conditional E-value: 0.00015 SNAP 40 qAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdlekA 134 + +nayk ++++A e +++ e+ +++++ +nay ++y++ d +A+e ek+ ei +e+ ++ + ++++ +++ +d++kA FUN_002345-T1 455 SLGNAYKSLGNFRKAIEYHEERLEIAIEVGNRVGEGNAYGSLGNAYRSLgDFRKAIEYHEKCLEIAIEASHRVGEGSAYGNLGNAFQSL-GDFRKA 549 55799999999999999999999999999999999999999999999877999999999999999999888888888889999999977.999999 PP SNAP 135 ieaYeqAadlyeqeeaealankcllkvAdlsaelekyekAieiye 179 ie+ ++ ++ + + +++ + + +l+++ kAie e FUN_002345-T1 550 IEYHQKHFEIAIEVGHRVGEGNAYGSLGIAYQSLGDFRKAIEYHE 594 999998777766666666666666666666666666666666665 PP == domain 8 score: 9.3 bits; conditional E-value: 0.0014 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+ ++++A e ++k+ e+ +++ + ++ay + +++++ d +A+e +k +ei +e g ++ + +++ y++ +d++ FUN_002345-T1 493 YGSLGNAYRSLGDFRKAIEYHEKCLEIAIEASHRVGEGSAYGNLGNAFQSLgDFRKAIEYHQKHFEIAIEVGHRVGEGNAYGSLGIAYQSL-GDFR 587 556689******************************************997799*******************************999977.**** PP SNAP 133 kAieaYeqAadl 144 kAie+ e+ ++ FUN_002345-T1 588 KAIEYHEKHLEI 599 ****99987765 PP == domain 9 score: 6.5 bits; conditional E-value: 0.0098 SNAP 38 ykqAAnayklakkwkeAgeaflkaAecqeklkekdeaanayveAakcykks.dpeeAvealekAieiytekgrfrraAklkkeiaelyekelqdle 132 y + +nay+ ++++A e ++k e+ +++ + +++y + ++y++ d ++Ave ek ei e g + + +++e y +++e FUN_002345-T1 653 YGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGHRVGEGSTYGNLGNAYQSLgDFQKAVEYHEKHLEIAKEVGDRAGEGIAYHNVGEEYFCL-GQFE 747 4445677777777788888888888888888888888888888888887765778888888888888888887777777777888877765.7888 PP SNAP 133 kAieaYeqAadlye 146 +A++++ A + ++ FUN_002345-T1 748 NALDNFVYAVEAFN 761 88888877777775 PP >> TPR_4 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 1.8 1.3e+03 3 20 .. 92 109 .. 90 111 .. 0.89 2 ? 0.1 0.0 3.6 2.5e+03 3 20 .. 132 149 .. 130 150 .. 0.86 3 ? 0.1 0.0 3.7 2.6e+03 3 20 .. 172 189 .. 170 190 .. 0.88 4 ? -1.1 0.0 9.2 6.5e+03 4 20 .. 213 229 .. 211 230 .. 0.85 5 ? 4.9 0.0 0.1 74 3 20 .. 252 269 .. 250 271 .. 0.89 6 ? 2.8 0.0 0.5 3.5e+02 3 20 .. 332 349 .. 330 351 .. 0.89 7 ? 0.1 0.0 3.6 2.5e+03 3 20 .. 372 389 .. 370 390 .. 0.86 8 ? 0.1 0.0 3.7 2.6e+03 3 20 .. 412 429 .. 410 430 .. 0.88 9 ? -1.1 0.0 9.2 6.5e+03 4 20 .. 493 509 .. 491 510 .. 0.85 10 ? 0.0 0.0 3.8 2.7e+03 4 20 .. 573 589 .. 571 590 .. 0.86 11 ? -0.0 0.0 4 2.8e+03 3 20 .. 612 629 .. 611 630 .. 0.89 12 ? 1.8 0.0 1 7.4e+02 3 20 .. 652 669 .. 650 671 .. 0.89 13 ? 2.1 0.0 0.81 5.7e+02 4 21 .. 693 710 .. 690 711 .. 0.86 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 1.8 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002345-T1 92 AYGNLGNAYRSLGDFRKA 109 6789**********9887 PP == domain 2 score: 0.1 bits; conditional E-value: 3.6 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a++ lGd+ A FUN_002345-T1 132 AYGSLGNAYQSLGDFRKA 149 67789*********9877 PP == domain 3 score: 0.1 bits; conditional E-value: 3.7 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ +++ lGd+ A FUN_002345-T1 172 AYGNLGNTYQSLGDFRKA 189 7889**********9877 PP == domain 4 score: -1.1 bits; conditional E-value: 9.2 TPR_4 4 llaLArallalGdldeA 20 + L+ a+ lGd+ A FUN_002345-T1 213 YGSLGNAYRSLGDFRKA 229 56799********9877 PP == domain 5 score: 4.9 bits; conditional E-value: 0.1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002345-T1 252 AYGNLGNAYWSLGDFRKA 269 789***********9887 PP == domain 6 score: 2.8 bits; conditional E-value: 0.5 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002345-T1 332 AYGNLGVAYQSLGDFRKA 349 789***********9887 PP == domain 7 score: 0.1 bits; conditional E-value: 3.6 TPR_4 3 allaLArallalGdldeA 20 a+ L+ a++ lGd+ A FUN_002345-T1 372 AYGSLGNAYQSLGDFRKA 389 67789*********9877 PP == domain 8 score: 0.1 bits; conditional E-value: 3.7 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ +++ lGd+ A FUN_002345-T1 412 AYGNLGNTYQSLGDFRKA 429 7889**********9877 PP == domain 9 score: -1.1 bits; conditional E-value: 9.2 TPR_4 4 llaLArallalGdldeA 20 + L+ a+ lGd+ A FUN_002345-T1 493 YGSLGNAYRSLGDFRKA 509 56799********9877 PP == domain 10 score: 0.0 bits; conditional E-value: 3.8 TPR_4 4 llaLArallalGdldeA 20 + L+ a++ lGd+ A FUN_002345-T1 573 YGSLGIAYQSLGDFRKA 589 5679*********9877 PP == domain 11 score: -0.0 bits; conditional E-value: 4 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a+ lGd+ A FUN_002345-T1 612 AYGNLGIAYDSLGDFRKA 629 6789**********9877 PP == domain 12 score: 1.8 bits; conditional E-value: 1 TPR_4 3 allaLArallalGdldeA 20 a+ +L+ a++ lGd+ A FUN_002345-T1 652 AYGNLGNAYQSLGDFRKA 669 6789**********9887 PP == domain 13 score: 2.1 bits; conditional E-value: 0.81 TPR_4 4 llaLArallalGdldeAr 21 + +L+ a++ lGd+ A FUN_002345-T1 693 YGNLGNAYQSLGDFQKAV 710 679***********9996 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.3 0.1 4.5 3.2e+03 14 27 .. 25 38 .. 18 44 .. 0.83 2 ? 1.7 0.0 0.56 4e+02 5 26 .. 56 77 .. 54 83 .. 0.87 3 ? 1.1 0.0 0.84 6e+02 5 30 .. 96 121 .. 94 126 .. 0.85 4 ? 4.0 0.0 0.11 78 5 30 .. 136 161 .. 134 167 .. 0.88 5 ? 0.8 0.0 1.1 7.6e+02 5 27 .. 176 198 .. 174 203 .. 0.82 6 ? 2.0 0.0 0.44 3.1e+02 5 28 .. 216 239 .. 214 246 .. 0.87 7 ? 3.3 0.0 0.18 1.3e+02 5 29 .. 256 280 .. 254 285 .. 0.87 8 ? 1.1 0.0 0.85 6e+02 5 28 .. 296 319 .. 294 325 .. 0.85 9 ? 0.6 0.0 1.2 8.7e+02 5 30 .. 336 361 .. 334 366 .. 0.84 10 ? 3.6 0.0 0.14 1e+02 5 30 .. 376 401 .. 374 407 .. 0.88 11 ? 1.4 0.0 0.67 4.7e+02 5 30 .. 416 441 .. 414 446 .. 0.83 12 ? 1.8 0.0 0.5 3.5e+02 5 27 .. 456 478 .. 454 483 .. 0.87 13 ? 2.3 0.0 0.35 2.5e+02 5 29 .. 496 520 .. 494 527 .. 0.85 14 ? 0.3 0.0 1.5 1.1e+03 5 25 .. 536 556 .. 534 562 .. 0.85 15 ? 0.6 0.0 1.2 8.4e+02 5 27 .. 576 598 .. 574 603 .. 0.84 16 ? -2.1 0.0 8.4 5.9e+03 8 29 .. 619 640 .. 615 644 .. 0.73 17 ? 1.2 0.1 0.81 5.7e+02 5 27 .. 656 678 .. 654 683 .. 0.87 18 ? 3.9 0.1 0.12 83 5 30 .. 696 721 .. 694 758 .. 0.87 Alignments for each domain: == domain 1 score: -1.3 bits; conditional E-value: 4.5 ARM_TT21_4th 14 qYkkAinYYeaalk 27 +++kAi+Y e+ l+ FUN_002345-T1 25 NFRKAIKYHEKHLE 38 799******99876 PP == domain 2 score: 1.7 bits; conditional E-value: 0.56 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaal 26 +G+a+ +++kAi+Y ++ FUN_002345-T1 56 LGNAYQSLCDFRKAIEYHQKHF 77 799**************98765 PP == domain 3 score: 1.1 bits; conditional E-value: 0.84 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y ++ l++ + FUN_002345-T1 96 LGNAYRSLGDFRKAIEYHDKHLEIAK 121 799999999********999887655 PP == domain 4 score: 4.0 bits; conditional E-value: 0.11 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002345-T1 136 LGNAYQSLGDFRKAIEYHEKCLEIAK 161 799****************9998765 PP == domain 5 score: 0.8 bits; conditional E-value: 1.1 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+++ +++kAi+Y e+ l+ FUN_002345-T1 176 LGNTYQSLGDFRKAIEYHEERLE 198 678888888999*****998776 PP == domain 6 score: 2.0 bits; conditional E-value: 0.44 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ l++ FUN_002345-T1 216 LGNAYRSLGDFRKAIEYHEKCLEI 239 699999999**********98875 PP == domain 7 score: 3.3 bits; conditional E-value: 0.18 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002345-T1 256 LGNAYWSLGDFRKAIEYHEKCLEIA 280 79999999***********998765 PP == domain 8 score: 1.1 bits; conditional E-value: 0.85 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G a+ +++kAi+Y ++ l++ FUN_002345-T1 296 LGVAYQSMADFRKAIQYHDKHLEI 319 789999999********9988765 PP == domain 9 score: 0.6 bits; conditional E-value: 1.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G a+ +++kAi+Y ++ l++ + FUN_002345-T1 336 LGVAYQSLGDFRKAIEYHDKHLEIAK 361 6889999999*******999887655 PP == domain 10 score: 3.6 bits; conditional E-value: 0.14 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kAi+Y e+ l++ + FUN_002345-T1 376 LGNAYQSLGDFRKAIEYHEKHLEIAK 401 799****************9988765 PP == domain 11 score: 1.4 bits; conditional E-value: 0.67 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+++ +++kAi+Y e+ l++ + FUN_002345-T1 416 LGNTYQSLGDFRKAIEYHEKHLEIAK 441 6888888889*********9988765 PP == domain 12 score: 1.8 bits; conditional E-value: 0.5 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y e+ l+ FUN_002345-T1 456 LGNAYKSLGNFRKAIEYHEERLE 478 699999999*********99876 PP == domain 13 score: 2.3 bits; conditional E-value: 0.35 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ l++ FUN_002345-T1 496 LGNAYRSLGDFRKAIEYHEKCLEIA 520 699999999**********998765 PP == domain 14 score: 0.3 bits; conditional E-value: 1.5 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaa 25 +G+a+ +++kAi+Y ++ FUN_002345-T1 536 LGNAFQSLGDFRKAIEYHQKH 556 799999999********9876 PP == domain 15 score: 0.6 bits; conditional E-value: 1.2 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G a+ +++kAi+Y e+ l+ FUN_002345-T1 576 LGIAYQSLGDFRKAIEYHEKHLE 598 5788888899********99876 PP == domain 16 score: -2.1 bits; conditional E-value: 8.4 ARM_TT21_4th 8 alvktHqYkkAinYYeaalkss 29 a+ +++kAi+Y e+ l++ FUN_002345-T1 619 AYDSLGDFRKAIEYQEKRLEIA 640 555566899*****99887765 PP == domain 17 score: 1.2 bits; conditional E-value: 0.81 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ +++kAi+Y + l+ FUN_002345-T1 656 LGNAYQSLGDFRKAIEYHAKHLE 678 799**************987765 PP == domain 18 score: 3.9 bits; conditional E-value: 0.12 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalksse 30 +G+a+ +++kA++Y e+ l++ + FUN_002345-T1 696 LGNAYQSLGDFQKAVEYHEKHLEIAK 721 799****************9988765 PP >> TPR_19 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 6 4.3e+03 24 46 .. 49 71 .. 22 74 .. 0.61 2 ? 1.1 0.0 1 7.4e+02 26 47 .. 91 112 .. 87 125 .. 0.82 3 ? 7.1 0.0 0.013 9.3 4 46 .. 143 191 .. 140 198 .. 0.93 4 ? 6.9 0.0 0.016 11 4 46 .. 223 271 .. 220 279 .. 0.85 5 ? 5.1 0.0 0.057 40 3 50 .. 262 315 .. 260 327 .. 0.85 6 ? 1.4 0.0 0.83 5.9e+02 24 47 .. 329 352 .. 300 367 .. 0.73 7 ? 1.4 0.0 0.79 5.6e+02 5 46 .. 344 391 .. 342 405 .. 0.74 8 ? 4.2 0.0 0.11 80 5 47 .. 384 432 .. 380 447 .. 0.86 9 ? 2.2 0.0 0.45 3.2e+02 5 46 .. 424 471 .. 420 475 .. 0.86 10 ? 2.5 0.0 0.38 2.7e+02 4 46 .. 503 551 .. 500 555 .. 0.75 11 ? 2.2 0.0 0.47 3.3e+02 5 46 .. 584 631 .. 580 642 .. 0.75 12 ? 3.1 0.0 0.24 1.7e+02 5 46 .. 624 671 .. 622 679 .. 0.75 13 ? -0.3 0.0 2.8 2e+03 30 46 .. 695 711 .. 692 722 .. 0.69 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 6 TPR_19 24 naearllLArallalgrldeAea 46 a+ +L++a+ l ++ +A++ FUN_002345-T1 49 EGSAYGNLGNAYQSLCDFRKAIE 71 45577788888888888888875 PP == domain 2 score: 1.1 bits; conditional E-value: 1 TPR_19 26 earllLArallalgrldeAeal 47 a+ +L++a+ lg++ +A++ FUN_002345-T1 91 NAYGNLGNAYRSLGDFRKAIEY 112 68899999999****9999985 PP == domain 3 score: 7.1 bits; conditional E-value: 0.013 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++++ lg++ +A++ FUN_002345-T1 143 LGDFRKAIEYHEKCLEIAKEvsdrvgEGSAYGNLGNTYQSLGDFRKAIE 191 59***************999999999999******************87 PP == domain 4 score: 6.9 bits; conditional E-value: 0.016 TPR_19 4 egdydeAlalLeqalae..dPd....naearllLArallalgrldeAea 46 gd+ +A+++ e+ l++ + + a+ +L++a+ lg++ +A++ FUN_002345-T1 223 LGDFRKAIEYHEKCLEIaiEAGhrvgEGSAYGNLGNAYWSLGDFRKAIE 271 699**********9988553335666999******************87 PP == domain 5 score: 5.1 bits; conditional E-value: 0.057 TPR_19 3 aegdydeAlalLeqalaedPd......naearllLArallalgrldeAealLaa 50 gd+ +A+++ e+ l+++ + a+ +L+ a+ + ++ +A++ ++ FUN_002345-T1 262 SLGDFRKAIEYHEKCLEIATEvsdqvgEGSAYGNLGVAYQSMADFRKAIQYHDK 315 579***************998888888999999999999999999999986555 PP == domain 6 score: 1.4 bits; conditional E-value: 0.83 TPR_19 24 naearllLArallalgrldeAeal 47 a+ +L+ a+ lg++ +A++ FUN_002345-T1 329 EGSAYGNLGVAYQSLGDFRKAIEY 352 566888999999999999999886 PP == domain 7 score: 1.4 bits; conditional E-value: 0.79 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ + l+++ + a+ L++a+ lg++ +A++ FUN_002345-T1 344 GDFRKAIEYHDKHLEIAKEvsdrvgEGSAYGSLGNAYQSLGDFRKAIE 391 677777777777666666666666677788889999999999999987 PP == domain 8 score: 4.2 bits; conditional E-value: 0.11 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAeal 47 gd+ +A+++ e+ l+++ + a+ +L++++ lg++ +A++ FUN_002345-T1 384 GDFRKAIEYHEKHLEIAKEvsdrvgEGSAYGNLGNTYQSLGDFRKAIEY 432 9999999999999999888888888999999***************985 PP == domain 9 score: 2.2 bits; conditional E-value: 0.45 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ L++a+ lg++ +A++ FUN_002345-T1 424 GDFRKAIEYHEKHLEIAKEvsdrvgEGSAYGSLGNAYKSLGNFRKAIE 471 899999999999888888877788888899999999999999999986 PP == domain 10 score: 2.5 bits; conditional E-value: 0.38 TPR_19 4 egdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a lg++ +A++ FUN_002345-T1 503 LGDFRKAIEYHEKCLEIAIEashrvgEGSAYGNLGNAFQSLGDFRKAIE 551 699**********998733323345588888888888888888888875 PP == domain 11 score: 2.2 bits; conditional E-value: 0.47 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L+ a+ lg++ +A++ FUN_002345-T1 584 GDFRKAIEYHEKHLEIAIEvgnrvgEGNAYGNLGIAYDSLGDFRKAIE 631 77777777777755553222233448899999***********99987 PP == domain 12 score: 3.1 bits; conditional E-value: 0.24 TPR_19 5 gdydeAlalLeqalaedPd......naearllLArallalgrldeAea 46 gd+ +A+++ e+ l+++ + a+ +L++a+ lg++ +A++ FUN_002345-T1 624 GDFRKAIEYQEKRLEIAKEvsdrvgEGNAYGNLGNAYQSLGDFRKAIE 671 5666666666665555555555555789999***************87 PP == domain 13 score: -0.3 bits; conditional E-value: 2.8 TPR_19 30 lLArallalgrldeAea 46 +L++a+ lg++ +A + FUN_002345-T1 695 NLGNAYQSLGDFQKAVE 711 67777777777777765 PP >> TPR_9 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 2.5 1.8e+03 33 58 .. 14 39 .. 12 46 .. 0.80 2 ? -1.1 0.0 4 2.8e+03 34 58 .. 95 119 .. 91 127 .. 0.73 3 ? 4.3 0.0 0.084 60 35 61 .. 136 162 .. 131 168 .. 0.84 4 ? 0.7 0.0 1.1 7.7e+02 36 59 .. 217 240 .. 212 247 .. 0.83 5 ? 2.4 0.0 0.32 2.3e+02 34 59 .. 255 280 .. 251 327 .. 0.74 6 ? 3.7 0.0 0.12 88 32 59 .. 333 360 .. 329 367 .. 0.80 7 ? 3.3 0.0 0.17 1.2e+02 32 52 .. 413 433 .. 376 447 .. 0.50 8 ? 0.9 0.0 0.98 7e+02 36 60 .. 497 521 .. 492 527 .. 0.82 9 ? -1.5 0.0 5.4 3.9e+03 33 51 .. 534 552 .. 530 557 .. 0.81 10 ? 3.6 0.0 0.14 96 35 56 .. 576 597 .. 571 602 .. 0.83 11 ? 1.7 0.0 0.53 3.8e+02 33 59 .. 614 640 .. 611 647 .. 0.79 12 ? 0.6 0.0 1.2 8.5e+02 33 51 .. 654 672 .. 649 680 .. 0.83 13 ? 3.5 0.0 0.14 1e+02 34 60 .. 695 721 .. 691 727 .. 0.81 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 2.5 TPR_9 33 rdrGllyaqlgcleaAladLeaylal 58 ++ + + + lg++ +A+++ e+ l++ FUN_002345-T1 14 QNLAYAFQSLGNFRKAIKYHEKHLEI 39 6778999*********9987776665 PP == domain 2 score: -1.1 bits; conditional E-value: 4 TPR_9 34 drGllyaqlgcleaAladLeaylal 58 + G +y lg++ +A+++ ++ l++ FUN_002345-T1 95 NLGNAYRSLGDFRKAIEYHDKHLEI 119 6788899999999999876666655 PP == domain 3 score: 4.3 bits; conditional E-value: 0.084 TPR_9 35 rGllyaqlgcleaAladLeaylalapd 61 G +y+ lg++ +A+++ e++l++a + FUN_002345-T1 136 LGNAYQSLGDFRKAIEYHEKCLEIAKE 162 5889******************99865 PP == domain 4 score: 0.7 bits; conditional E-value: 1.1 TPR_9 36 GllyaqlgcleaAladLeaylala 59 G +y lg++ +A+++ e++l++a FUN_002345-T1 217 GNAYRSLGDFRKAIEYHEKCLEIA 240 678899*********999999887 PP == domain 5 score: 2.4 bits; conditional E-value: 0.32 TPR_9 34 drGllyaqlgcleaAladLeaylala 59 + G +y lg++ +A+++ e++l++a FUN_002345-T1 255 NLGNAYWSLGDFRKAIEYHEKCLEIA 280 56677777888888888777777665 PP == domain 6 score: 3.7 bits; conditional E-value: 0.12 TPR_9 32 rrdrGllyaqlgcleaAladLeaylala 59 + + G +y+ lg++ +A+++ ++ l++a FUN_002345-T1 333 YGNLGVAYQSLGDFRKAIEYHDKHLEIA 360 6688**************9876666655 PP == domain 7 score: 3.3 bits; conditional E-value: 0.17 TPR_9 32 rrdrGllyaqlgcleaAladL 52 + + G y+ lg++ +A+++ FUN_002345-T1 413 YGNLGNTYQSLGDFRKAIEYH 433 334444555555555555554 PP == domain 8 score: 0.9 bits; conditional E-value: 0.98 TPR_9 36 GllyaqlgcleaAladLeaylalap 60 G +y lg++ +A+++ e++l++a FUN_002345-T1 497 GNAYRSLGDFRKAIEYHEKCLEIAI 521 678899**********999998875 PP == domain 9 score: -1.5 bits; conditional E-value: 5.4 TPR_9 33 rdrGllyaqlgcleaAlad 51 + G + + lg++ +A+++ FUN_002345-T1 534 GNLGNAFQSLGDFRKAIEY 552 5678889999999999875 PP == domain 10 score: 3.6 bits; conditional E-value: 0.14 TPR_9 35 rGllyaqlgcleaAladLeayl 56 G++y+ lg++ +A+++ e+ l FUN_002345-T1 576 LGIAYQSLGDFRKAIEYHEKHL 597 69*************9866655 PP == domain 11 score: 1.7 bits; conditional E-value: 0.53 TPR_9 33 rdrGllyaqlgcleaAladLeaylala 59 + G++y lg++ +A+++ e+ l++a FUN_002345-T1 614 GNLGIAYDSLGDFRKAIEYQEKRLEIA 640 6789*************9877666655 PP == domain 12 score: 0.6 bits; conditional E-value: 1.2 TPR_9 33 rdrGllyaqlgcleaAlad 51 + G +y+ lg++ +A+++ FUN_002345-T1 654 GNLGNAYQSLGDFRKAIEY 672 567999**********986 PP == domain 13 score: 3.5 bits; conditional E-value: 0.14 TPR_9 34 drGllyaqlgcleaAladLeaylalap 60 + G +y+ lg++++A+++ e+ l++a FUN_002345-T1 695 NLGNAYQSLGDFQKAVEYHEKHLEIAK 721 67999***********99888887775 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 1.6 1.2e+03 220 243 .. 15 38 .. 8 42 .. 0.87 2 ? -1.4 0.0 2.4 1.7e+03 219 242 .. 54 77 .. 49 81 .. 0.75 3 ? 1.1 0.0 0.42 3e+02 219 246 .. 94 121 .. 90 125 .. 0.87 4 ? 1.1 0.0 0.43 3.1e+02 218 245 .. 133 160 .. 128 165 .. 0.84 5 ? -3.1 0.0 8.4 5.9e+03 220 240 .. 175 195 .. 170 200 .. 0.60 6 ? -0.4 0.0 1.2 8.8e+02 219 241 .. 214 236 .. 210 242 .. 0.86 7 ? 0.0 0.0 0.91 6.5e+02 219 242 .. 254 277 .. 249 285 .. 0.85 8 ? 1.5 0.0 0.32 2.2e+02 219 246 .. 334 361 .. 319 365 .. 0.88 9 ? 3.2 0.0 0.097 69 218 246 .. 373 401 .. 368 405 .. 0.88 10 ? -0.3 0.0 1.2 8.2e+02 220 246 .. 415 441 .. 410 445 .. 0.81 11 ? -0.4 0.0 1.2 8.5e+02 219 242 .. 454 477 .. 449 481 .. 0.81 12 ? -0.3 0.0 1.2 8.3e+02 219 241 .. 494 516 .. 490 524 .. 0.86 13 ? 0.4 0.0 0.68 4.8e+02 218 242 .. 533 557 .. 519 561 .. 0.85 14 ? 0.8 0.0 0.52 3.7e+02 219 243 .. 574 598 .. 570 601 .. 0.87 15 ? -1.1 0.0 2 1.4e+03 220 246 .. 615 641 .. 611 646 .. 0.86 16 ? 0.2 0.0 0.78 5.6e+02 219 243 .. 654 678 .. 649 681 .. 0.87 17 ? 2.3 0.0 0.18 1.3e+02 219 246 .. 694 721 .. 689 723 .. 0.88 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 1.6 TPR_15 220 ayAaAllllgqnrkALpyfrkkaa 243 +A A+ lg+ rkA +y +k+++ FUN_002345-T1 15 NLAYAFQSLGNFRKAIKYHEKHLE 38 68999***************9976 PP == domain 2 score: -1.4 bits; conditional E-value: 2.4 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ l + rkA +y +k+ FUN_002345-T1 54 GNLGNAYQSLCDFRKAIEYHQKHF 77 557788888888888888888875 PP == domain 3 score: 1.1 bits; conditional E-value: 0.42 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y k+++ +k FUN_002345-T1 94 GNLGNAYRSLGDFRKAIEYHDKHLEIAK 121 56899****************9988765 PP == domain 4 score: 1.1 bits; conditional E-value: 0.43 TPR_15 218 weayAaAllllgqnrkALpyfrkkaaqn 245 ++ ++ A+ lg+ rkA +y +k ++ + FUN_002345-T1 133 YGSLGNAYQSLGDFRKAIEYHEKCLEIA 160 567999**************99966654 PP == domain 5 score: -3.1 bits; conditional E-value: 8.4 TPR_15 220 ayAaAllllgqnrkALpyfrk 240 ++ + lg+ rkA +y + FUN_002345-T1 175 NLGNTYQSLGDFRKAIEYHEE 195 455566666666666666655 PP == domain 6 score: -0.4 bits; conditional E-value: 1.2 TPR_15 219 eayAaAllllgqnrkALpyfrkk 241 + ++ A+ lg+ rkA +y +k FUN_002345-T1 214 GSLGNAYRSLGDFRKAIEYHEKC 236 67899**************9985 PP == domain 7 score: 0.0 bits; conditional E-value: 0.91 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ lg+ rkA +y +k + FUN_002345-T1 254 GNLGNAYWSLGDFRKAIEYHEKCL 277 67899**************99855 PP == domain 8 score: 1.5 bits; conditional E-value: 0.32 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y k+++ +k FUN_002345-T1 334 GNLGVAYQSLGDFRKAIEYHDKHLEIAK 361 67899*****************988765 PP == domain 9 score: 3.2 bits; conditional E-value: 0.097 TPR_15 218 weayAaAllllgqnrkALpyfrkkaaqnk 246 ++ ++ A+ lg+ rkA +y +k+++ +k FUN_002345-T1 373 YGSLGNAYQSLGDFRKAIEYHEKHLEIAK 401 567999*****************988766 PP == domain 10 score: -0.3 bits; conditional E-value: 1.2 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqnk 246 ++ + lg+ rkA +y +k+++ +k FUN_002345-T1 415 NLGNTYQSLGDFRKAIEYHEKHLEIAK 441 577889999999999999999987765 PP == domain 11 score: -0.4 bits; conditional E-value: 1.2 TPR_15 219 eayAaAllllgqnrkALpyfrkka 242 + ++ A+ lg+ rkA +y + ++ FUN_002345-T1 454 GSLGNAYKSLGNFRKAIEYHEERL 477 678899999999999999988765 PP == domain 12 score: -0.3 bits; conditional E-value: 1.2 TPR_15 219 eayAaAllllgqnrkALpyfrkk 241 + ++ A+ lg+ rkA +y +k FUN_002345-T1 494 GSLGNAYRSLGDFRKAIEYHEKC 516 67899**************9985 PP == domain 13 score: 0.4 bits; conditional E-value: 0.68 TPR_15 218 weayAaAllllgqnrkALpyfrkka 242 ++ ++ A+ lg+ rkA +y +k+ FUN_002345-T1 533 YGNLGNAFQSLGDFRKAIEYHQKHF 557 5678999999**********99986 PP == domain 14 score: 0.8 bits; conditional E-value: 0.52 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y +k+++ FUN_002345-T1 574 GSLGIAYQSLGDFRKAIEYHEKHLE 598 56889****************9975 PP == domain 15 score: -1.1 bits; conditional E-value: 2 TPR_15 220 ayAaAllllgqnrkALpyfrkkaaqnk 246 ++ A+ lg+ rkA +y +k+++ +k FUN_002345-T1 615 NLGIAYDSLGDFRKAIEYQEKRLEIAK 641 67889**************99887665 PP == domain 16 score: 0.2 bits; conditional E-value: 0.78 TPR_15 219 eayAaAllllgqnrkALpyfrkkaa 243 + ++ A+ lg+ rkA +y k+++ FUN_002345-T1 654 GNLGNAYQSLGDFRKAIEYHAKHLE 678 56899**************999875 PP == domain 17 score: 2.3 bits; conditional E-value: 0.18 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ +kA +y +k+++ +k FUN_002345-T1 694 GNLGNAYQSLGDFQKAVEYHEKHLEIAK 721 67899*****************998765 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 2.2 1.5e+03 81 105 .. 84 108 .. 35 112 .. 0.58 2 ? 5.7 0.0 0.035 25 75 108 .. 118 151 .. 105 159 .. 0.85 3 ? 2.3 0.0 0.37 2.7e+02 75 107 .. 158 190 .. 148 192 .. 0.87 4 ? 1.1 0.0 0.91 6.4e+02 75 108 .. 198 231 .. 191 239 .. 0.77 5 ? -1.0 0.0 4 2.9e+03 74 107 .. 274 310 .. 242 319 .. 0.75 6 ? 0.6 0.0 1.3 9.4e+02 75 107 .. 318 350 .. 303 352 .. 0.84 7 ? 4.8 0.0 0.065 46 75 107 .. 358 390 .. 351 392 .. 0.89 8 ? 2.5 0.0 0.34 2.4e+02 75 107 .. 398 430 .. 390 432 .. 0.88 9 ? 2.8 0.0 0.26 1.9e+02 75 107 .. 438 470 .. 431 472 .. 0.88 10 ? 1.1 0.0 0.91 6.4e+02 75 108 .. 478 511 .. 471 519 .. 0.77 11 ? -1.9 0.0 7.5 5.3e+03 75 106 .. 558 589 .. 535 591 .. 0.67 12 ? 3.3 0.0 0.18 1.3e+02 74 107 .. 636 670 .. 612 672 .. 0.86 13 ? 1.7 0.0 0.57 4.1e+02 51 93 .. 1140 1182 .. 1134 1191 .. 0.76 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 2.2 GGDEF_2 81 rrrlggitvriGvGrpveglaglrr 105 +r+g+ +++ +G+++++l ++r+ FUN_002345-T1 84 GHRVGEGNAYGNLGNAYRSLGDFRK 108 3333333333334444444444444 PP == domain 2 score: 5.7 bits; conditional E-value: 0.035 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSyr 108 e+++++++r+g+ +++ +G+++++l ++r++ + FUN_002345-T1 118 EIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAIE 151 899***************************9975 PP == domain 3 score: 2.3 bits; conditional E-value: 0.37 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002345-T1 158 EIAKEVSDRVGEGSAYGNLGNTYQSLGDFRKAI 190 789999999999999999************986 PP == domain 4 score: 1.1 bits; conditional E-value: 0.91 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSyr 108 e++ ++ +r+g+ +++ +G+++++l ++r++ + FUN_002345-T1 198 EIAIEVGNRVGEGNAYGSLGNAYRSLGDFRKAIE 231 5556666777778888899999999999999865 PP == domain 5 score: -1.0 bits; conditional E-value: 4 GGDEF_2 74 e...ellerlrrrlggitvriGvGrpveglaglrrSy 107 e e+++++++++g+ +++ +G ++++ a++r++ FUN_002345-T1 274 EkclEIATEVSDQVGEGSAYGNLGVAYQSMADFRKAI 310 1455788888888888888888888888888888876 PP == domain 6 score: 0.6 bits; conditional E-value: 1.3 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G ++++l ++r++ FUN_002345-T1 318 EIAREVSDRVGEGSAYGNLGVAYQSLGDFRKAI 350 899999****99999999***********9985 PP == domain 7 score: 4.8 bits; conditional E-value: 0.065 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002345-T1 358 EIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAI 390 8999**************************986 PP == domain 8 score: 2.5 bits; conditional E-value: 0.34 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++++l ++r++ FUN_002345-T1 398 EIAKEVSDRVGEGSAYGNLGNTYQSLGDFRKAI 430 8999999*****9*****************986 PP == domain 9 score: 2.8 bits; conditional E-value: 0.26 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+++ +l ++r++ FUN_002345-T1 438 EIAKEVSDRVGEGSAYGSLGNAYKSLGNFRKAI 470 8999**************************986 PP == domain 10 score: 1.1 bits; conditional E-value: 0.91 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSyr 108 e++ ++ +r+g+ +++ +G+++++l ++r++ + FUN_002345-T1 478 EIAIEVGNRVGEGNAYGSLGNAYRSLGDFRKAIE 511 5556666777778888899999999999999865 PP == domain 11 score: -1.9 bits; conditional E-value: 7.5 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrS 106 e++ ++ +r+g+ +++ +G ++++l ++r++ FUN_002345-T1 558 EIAIEVGHRVGEGNAYGSLGIAYQSLGDFRKA 589 45555556666667777777788888888876 PP == domain 12 score: 3.3 bits; conditional E-value: 0.18 GGDEF_2 74 e.ellerlrrrlggitvriGvGrpveglaglrrSy 107 + e+++++++r+g+ +++ +G+++++l ++r++ FUN_002345-T1 636 RlEIAKEVSDRVGEGNAYGNLGNAYQSLGDFRKAI 670 25899999*****99****************9985 PP == domain 13 score: 1.7 bits; conditional E-value: 0.57 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvriGv 93 +l+a ++ lv+l+++ddea+ e+++r+ ++l++ t++++v FUN_002345-T1 1140 AFLAAGARSVLVALWALDDEAT-MEFMKRFYQHLKEgNTASAAV 1182 56777788899********864.688888888888766666665 PP >> TPR_IF140-IFT172 IF140/IFT172 TPR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 0.55 3.9e+02 70 138 .. 36 112 .. 10 123 .. 0.60 2 ? 3.8 0.0 0.036 25 86 143 .. 99 157 .. 79 169 .. 0.82 3 ! 6.1 0.5 0.0072 5.1 85 150 .. 138 204 .. 109 316 .. 0.60 4 ? 3.7 0.3 0.039 27 170 247 .. 307 392 .. 196 395 .. 0.44 5 ! 6.1 0.1 0.0071 5 71 141 .. 357 435 .. 339 446 .. 0.69 6 ! 5.9 0.2 0.008 5.7 138 214 .. 632 715 .. 567 777 .. 0.50 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 0.55 TPR_IF140-IFT172 70 qLglldeaekllksckrydllnklyqasgkwdkalevaekk........drihlrktyynyakhleakgdieeaikl 138 +L++ ea + + + + y l + yq+ + + ka+e +k+ r+ ++y n + + gd+++ai++ FUN_002345-T1 36 HLEIAIEAGHRVGEGSAYGNLGNAYQSLCDFRKAIEYHQKHfeiaievgHRVGEGNAYGNLGNAYRSLGDFRKAIEY 112 45666666666666666666777777776666666665554111111113333344455555555555555555554 PP == domain 2 score: 3.8 bits; conditional E-value: 0.036 TPR_IF140-IFT172 86 rydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyekse 143 y l ++ +a + dk le+a++ +dr+ ++y + ++ gd+++ai+++ek+ FUN_002345-T1 99 AYRSLGDFRKAIEYHDKHLEIAKEvSDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKCL 157 57778888888888899999997637999999999999999999999999999999885 PP == domain 3 score: 6.1 bits; conditional E-value: 0.0072 TPR_IF140-IFT172 85 krydllnklyqasgkwdkalevaek.kdrihlrktyynyakhleakgdieeaiklyeksethrfevP 150 + y+ l ++ +a + +k le+a++ +dr+ ++y n ++ ++ gd+++ai+++e+ ev FUN_002345-T1 138 NAYQSLGDFRKAIEYHEKCLEIAKEvSDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEERLEIAIEVG 204 3344455555555555566677765379999999999999999999999999999987666556655 PP == domain 4 score: 3.7 bits; conditional E-value: 0.039 TPR_IF140-IFT172 170 kelkkWwaqylestgele....talkyyeaaedylslvrvlCyledlek....aaelanetgdkaacyhlarqyenadeikeaihf 247 ++ ++ ++le + e+ + y + y sl e +k a+e+++ g+ +a l+ y++ +++++ai++ FUN_002345-T1 307 RKAIQYHDKHLEIAREVSdrvgEGSAYGNLGVAYQSLGDFRKAIEYHDKhleiAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAIEY 392 33444444444444333211101222222223333333322222222220000222222222233444445555555555555444 PP == domain 5 score: 6.1 bits; conditional E-value: 0.0071 TPR_IF140-IFT172 71 Lglldeaekllksckrydllnklyqasgkwdka.......levaek.kdrihlrktyynyakhleakgdieeaiklyek 141 L++ +e + + + + y l + yq+ g + ka le+a++ +dr+ ++y n ++ ++ gd+++ai+++ek FUN_002345-T1 357 LEIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAieyhekhLEIAKEvSDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEK 435 5555555555566666666666666666655551111111556654369999999999999999999999999999887 PP == domain 6 score: 5.9 bits; conditional E-value: 0.008 TPR_IF140-IFT172 138 lyeksethrfevPrlLfddte..aL.esyvkkskdkelkkWwaqylestgele....talkyyeaaedylslvrvlCyledlek 214 + ek ev + + ++ +L ++y + + ++ + a++le + e+ + y + + y sl + +e ek FUN_002345-T1 632 YQEKRLEIAKEVSDRVGEGNAygNLgNAYQSLGDFRKAIEYHAKHLEIAIEVGhrvgEGSTYGNLGNAYQSLGDFQKAVEYHEK 715 333333333333322222221112211222222223333333333333333220000122222333333333333333333333 PP >> DUF6377 Domain of unknown function (DUF6377) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 3.2 2.3e+03 10 45 .. 11 46 .. 6 61 .. 0.87 2 ? -0.7 0.0 1.7 1.2e+03 6 45 .. 87 126 .. 82 128 .. 0.87 3 ? 3.2 0.0 0.11 76 6 45 .. 127 166 .. 122 172 .. 0.89 4 ? 0.3 0.0 0.82 5.8e+02 5 45 .. 166 206 .. 162 213 .. 0.87 5 ? 1.6 0.0 0.34 2.4e+02 5 45 .. 206 246 .. 202 249 .. 0.87 6 ? 2.1 0.0 0.23 1.7e+02 7 44 .. 248 285 .. 243 289 .. 0.89 7 ? -2.0 0.0 4.2 3e+03 5 45 .. 286 326 .. 282 328 .. 0.86 8 ? -1.1 0.0 2.2 1.5e+03 6 45 .. 327 366 .. 322 372 .. 0.87 9 ? -0.1 0.0 1.1 7.8e+02 6 45 .. 367 406 .. 362 412 .. 0.88 10 ? 1.1 0.0 0.48 3.4e+02 5 45 .. 406 446 .. 402 453 .. 0.88 11 ? 1.2 0.0 0.45 3.2e+02 5 45 .. 486 526 .. 482 531 .. 0.86 12 ? -0.4 0.0 1.3 9.4e+02 6 45 .. 527 566 .. 522 576 .. 0.87 13 ? -1.7 0.0 3.4 2.4e+03 7 46 .. 568 607 .. 562 640 .. 0.83 14 ? -2.5 0.0 5.9 4.2e+03 5 45 .. 606 646 .. 602 651 .. 0.84 15 ? -1.4 0.0 2.7 1.9e+03 6 45 .. 647 686 .. 642 697 .. 0.86 16 ? -0.7 0.0 1.7 1.2e+03 8 45 .. 689 726 .. 682 728 .. 0.85 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 3.2 DUF6377 10 aallkLaellyeegdierAykYikvaledakfynar 45 ++La + g++++A kY + le a + r FUN_002345-T1 11 KGYQNLAYAFQSLGNFRKAIKYHEKHLEIAIEAGHR 46 56799*****************99999988877766 PP == domain 2 score: -0.7 bits; conditional E-value: 1.7 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e a +L++ + gd+++A +Y + le ak +++r FUN_002345-T1 87 VGEGNAYGNLGNAYRSLGDFRKAIEYHDKHLEIAKEVSDR 126 66888999********************999999988776 PP == domain 3 score: 3.2 bits; conditional E-value: 0.11 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L++ + gd+++A +Y + +le ak +++r FUN_002345-T1 127 VGEGSAYGSLGNAYQSLGDFRKAIEYHEKCLEIAKEVSDR 166 668899999*************************999887 PP == domain 4 score: 0.3 bits; conditional E-value: 0.82 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L++++ gd+++A +Y + le a +++r FUN_002345-T1 166 RVGEGSAYGNLGNTYQSLGDFRKAIEYHEERLEIAIEVGNR 206 567889999*******************9999999988887 PP == domain 5 score: 1.6 bits; conditional E-value: 0.34 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 + e a +L++ + gd+++A +Y + +le a + r FUN_002345-T1 206 RVGEGNAYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEAGHR 246 6678899999***********************99888776 PP == domain 6 score: 2.1 bits; conditional E-value: 0.23 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfyna 44 e +a +L++ + gd+++A +Y + +le a+ +++ FUN_002345-T1 248 GEGSAYGNLGNAYWSLGDFRKAIEYHEKCLEIATEVSD 285 6788999************************9998765 PP == domain 7 score: -2.0 bits; conditional E-value: 4.2 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 ++ e +a +L+ + + d+++A +Y + le a+ +++r FUN_002345-T1 286 QVGEGSAYGNLGVAYQSMADFRKAIQYHDKHLEIAREVSDR 326 6778899999*****************99999999887766 PP == domain 8 score: -1.1 bits; conditional E-value: 2.2 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L+ + gd+++A +Y + le ak +++r FUN_002345-T1 327 VGEGSAYGNLGVAYQSLGDFRKAIEYHDKHLEIAKEVSDR 366 668889999**99999************999999988877 PP == domain 9 score: -0.1 bits; conditional E-value: 1.1 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L++ + gd+++A +Y + le ak +++r FUN_002345-T1 367 VGEGSAYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDR 406 668899999********************99999998877 PP == domain 10 score: 1.1 bits; conditional E-value: 0.48 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L++++ gd+++A +Y + le ak +++r FUN_002345-T1 406 RVGEGSAYGNLGNTYQSLGDFRKAIEYHEKHLEIAKEVSDR 446 567889999***********************999998877 PP == domain 11 score: 1.2 bits; conditional E-value: 0.45 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 + e a +L++ + gd+++A +Y + +le a + r FUN_002345-T1 486 RVGEGNAYGSLGNAYRSLGDFRKAIEYHEKCLEIAIEASHR 526 6678899999**********************999876665 PP == domain 12 score: -0.4 bits; conditional E-value: 1.3 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e +a +L++ + gd+++A +Y + +e a ++ r FUN_002345-T1 527 VGEGSAYGNLGNAFQSLGDFRKAIEYHQKHFEIAIEVGHR 566 67889999********************999988888776 PP == domain 13 score: -1.7 bits; conditional E-value: 3.4 DUF6377 7 kenaallkLaellyeegdierAykYikvaledakfynarl 46 e a +L+ + gd+++A +Y + le a +++r+ FUN_002345-T1 568 GEGNAYGSLGIAYQSLGDFRKAIEYHEKHLEIAIEVGNRV 607 5777888888888888999999999999999888888775 PP == domain 14 score: -2.5 bits; conditional E-value: 5.9 DUF6377 5 atkenaallkLaellyeegdierAykYikvaledakfynar 45 + e a +L+ + gd+++A +Y + le ak +++r FUN_002345-T1 606 RVGEGNAYGNLGIAYDSLGDFRKAIEYQEKRLEIAKEVSDR 646 566888899999999999*********99999999988776 PP == domain 15 score: -1.4 bits; conditional E-value: 2.7 DUF6377 6 tkenaallkLaellyeegdierAykYikvaledakfynar 45 + e a +L++ + gd+++A +Y le a ++ r FUN_002345-T1 647 VGEGNAYGNLGNAYQSLGDFRKAIEYHAKHLEIAIEVGHR 686 66889999******************99999888877766 PP == domain 16 score: -0.7 bits; conditional E-value: 1.7 DUF6377 8 enaallkLaellyeegdierAykYikvaledakfynar 45 e + +L++ + gd+++A +Y + le ak +++r FUN_002345-T1 689 EGSTYGNLGNAYQSLGDFQKAVEYHEKHLEIAKEVGDR 726 556667899999999**************999998877 PP >> Sec1 Sec1 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.032 23 301 352 .. 91 143 .. 55 167 .. 0.71 2 ? -0.6 0.0 1.1 7.8e+02 309 338 .. 299 328 .. 271 333 .. 0.85 3 ? 2.5 0.0 0.13 91 307 339 .. 337 369 .. 307 405 .. 0.70 4 ? 3.8 0.0 0.05 35 302 351 .. 372 422 .. 346 447 .. 0.64 5 ? 2.2 0.0 0.16 1.1e+02 283 333 .. 670 723 .. 617 730 .. 0.59 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.032 Sec1 301 esiadlkdfvekLpelqeekkklslHtnlaeellkiikk.rkldellelEqdl 352 + +l ++ ++L+++++ + ++H+++a e+++++ + + l++ q+l FUN_002345-T1 91 NAYGNLGNAYRSLGDFRKAIEYHDKHLEIAKEVSDRVGEgSAYGSLGNAYQSL 143 55677889999************************998733333444444444 PP == domain 2 score: -0.6 bits; conditional E-value: 1.1 Sec1 309 fvekLpelqeekkklslHtnlaeellkiik 338 + +++ ++++ + ++H+++a e+++++ FUN_002345-T1 299 AYQSMADFRKAIQYHDKHLEIAREVSDRVG 328 6688999******************99986 PP == domain 3 score: 2.5 bits; conditional E-value: 0.13 Sec1 307 kdfvekLpelqeekkklslHtnlaeellkiikk 339 + ++L+++++ + ++H+++a e+++++ + FUN_002345-T1 337 GVAYQSLGDFRKAIEYHDKHLEIAKEVSDRVGE 369 556678889999999999999999999888866 PP == domain 4 score: 3.8 bits; conditional E-value: 0.05 Sec1 302 siadlkdfvekLpelqeekkklslHtnlaeellkiikk.rkldellelEqd 351 l ++ ++L+++++ + ++H+++a e+++++ + + +l+++ q+ FUN_002345-T1 372 AYGSLGNAYQSLGDFRKAIEYHEKHLEIAKEVSDRVGEgSAYGNLGNTYQS 422 556677888999999999999999999999999998763333344444444 PP == domain 5 score: 2.2 bits; conditional E-value: 0.16 Sec1 283 kelkaknaelkrkgaks....sesiadlkdfvekLpelqeekkklslHtnlaeel 333 e+ ak+ e+ ++ + ++ +l ++ ++L+++q+ + ++H+++a e+ FUN_002345-T1 670 IEYHAKHLEIAI-EVGHrvgeGSTYGNLGNAYQSLGDFQKAVEYHEKHLEIAKEV 723 333333322222.222244556778888888888888888888888888888875 PP >> YebG YebG protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.8 0.0 0.11 79 22 40 .. 107 125 .. 105 133 .. 0.84 2 ? -0.3 0.0 2 1.4e+03 22 40 .. 147 165 .. 145 172 .. 0.83 3 ? -0.7 0.0 2.8 2e+03 23 41 .. 268 286 .. 266 292 .. 0.82 4 ? 2.5 0.0 0.29 2e+02 22 40 .. 307 325 .. 299 332 .. 0.82 5 ? 3.8 0.0 0.11 79 22 40 .. 347 365 .. 345 373 .. 0.84 6 ? -0.7 0.0 2.7 1.9e+03 22 40 .. 387 405 .. 385 412 .. 0.82 7 ? -0.7 0.0 2.7 1.9e+03 22 40 .. 427 445 .. 425 452 .. 0.82 Alignments for each domain: == domain 1 score: 3.8 bits; conditional E-value: 0.11 YebG 22 KkeADayDkmLdlAdnLad 40 +k+ + +Dk L++A++++d FUN_002345-T1 107 RKAIEYHDKHLEIAKEVSD 125 577789*********9987 PP == domain 2 score: -0.3 bits; conditional E-value: 2 YebG 22 KkeADayDkmLdlAdnLad 40 +k+ + + k L++A++++d FUN_002345-T1 147 RKAIEYHEKCLEIAKEVSD 165 5677889********9987 PP == domain 3 score: -0.7 bits; conditional E-value: 2.8 YebG 23 keADayDkmLdlAdnLadl 41 k+ + + k L++A +++d FUN_002345-T1 268 KAIEYHEKCLEIATEVSDQ 286 677889*******999875 PP == domain 4 score: 2.5 bits; conditional E-value: 0.29 YebG 22 KkeADayDkmLdlAdnLad 40 +k+ +Dk L++A +++d FUN_002345-T1 307 RKAIQYHDKHLEIAREVSD 325 5666789*******99987 PP == domain 5 score: 3.8 bits; conditional E-value: 0.11 YebG 22 KkeADayDkmLdlAdnLad 40 +k+ + +Dk L++A++++d FUN_002345-T1 347 RKAIEYHDKHLEIAKEVSD 365 577789*********9987 PP == domain 6 score: -0.7 bits; conditional E-value: 2.7 YebG 22 KkeADayDkmLdlAdnLad 40 +k+ + + k L++A++++d FUN_002345-T1 387 RKAIEYHEKHLEIAKEVSD 405 5677889********9987 PP == domain 7 score: -0.7 bits; conditional E-value: 2.7 YebG 22 KkeADayDkmLdlAdnLad 40 +k+ + + k L++A++++d FUN_002345-T1 427 RKAIEYHEKHLEIAKEVSD 445 5677889********9987 PP >> DHR-2_Lobe_A DHR-2, Lobe A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.087 61 108 152 .. 146 190 .. 133 191 .. 0.86 2 ? 0.4 0.0 1.4 1e+03 112 152 .. 270 310 .. 262 312 .. 0.89 3 ? -1.5 0.0 5.6 4e+03 112 152 .. 350 390 .. 339 392 .. 0.82 4 ? 1.0 0.0 0.95 6.7e+02 108 152 .. 386 430 .. 373 432 .. 0.85 5 ? 0.8 0.0 1.1 8e+02 108 152 .. 426 470 .. 415 471 .. 0.83 6 ? -1.8 0.0 6.8 4.8e+03 112 152 .. 510 550 .. 497 562 .. 0.83 7 ? -0.7 0.0 3.2 2.3e+03 113 152 .. 631 670 .. 623 671 .. 0.87 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.087 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + k e++E + e+ k+++ + +Y +l ++++ l ++ + i FUN_002345-T1 146 FRKAIEYHEKCLEIAKEVSDRVGEGSAYGNLGNTYQSLGDFRKAI 190 556679*******************************99987766 PP == domain 2 score: 0.4 bits; conditional E-value: 1.4 DHR-2_Lobe_A 112 aelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e++E + e+ +++ + +Y +l +++ +a++ + i FUN_002345-T1 270 IEYHEKCLEIATEVSDQVGEGSAYGNLGVAYQSMADFRKAI 310 589*******************************9998776 PP == domain 3 score: -1.5 bits; conditional E-value: 5.6 DHR-2_Lobe_A 112 aelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e+++ e+ k+++ + +Y +l ++++ l ++ + i FUN_002345-T1 350 IEYHDKHLEIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAI 390 57888889999999999999999999999999999887766 PP == domain 4 score: 1.0 bits; conditional E-value: 0.95 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + k e++E e+ k+++ + +Y +l ++++ l ++ + i FUN_002345-T1 386 FRKAIEYHEKHLEIAKEVSDRVGEGSAYGNLGNTYQSLGDFRKAI 430 55666999****************************999987766 PP == domain 5 score: 0.8 bits; conditional E-value: 1.1 DHR-2_Lobe_A 108 ylkkaelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 + k e++E e+ k+++ + +Y +l +++k l ++ + i FUN_002345-T1 426 FRKAIEYHEKHLEIAKEVSDRVGEGSAYGSLGNAYKSLGNFRKAI 470 55667999****************************998886665 PP == domain 6 score: -1.8 bits; conditional E-value: 6.8 DHR-2_Lobe_A 112 aelyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e++E + e+ +++ + +Y +l ++++ l ++ + i FUN_002345-T1 510 IEYHEKCLEIAIEASHRVGEGSAYGNLGNAFQSLGDFRKAI 550 58899999999999999999999999999999888876665 PP == domain 7 score: -0.7 bits; conditional E-value: 3.2 DHR-2_Lobe_A 113 elyElaielyklllpiyekkrdYkklseihkklaelyeki 152 e+ E e+ k+++ + ++Y +l ++++ l ++ + i FUN_002345-T1 631 EYQEKRLEIAKEVSDRVGEGNAYGNLGNAYQSLGDFRKAI 670 88999999***********************999987765 PP >> REGB_T4 T4-page Endoribonuclease RegB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.0 0.37 2.6e+02 59 105 .. 154 200 .. 145 203 .. 0.88 2 ? -2.1 0.0 7.5 5.3e+03 60 105 .. 275 320 .. 268 324 .. 0.84 3 ? -1.6 0.0 5.5 3.9e+03 62 105 .. 357 400 .. 347 408 .. 0.81 4 ? 0.8 0.0 0.98 7e+02 61 105 .. 436 480 .. 426 483 .. 0.84 5 ? 1.2 0.0 0.75 5.3e+02 67 106 .. 602 641 .. 585 648 .. 0.77 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 0.37 REGB_T4 59 eyvfellkklkekvkevveflelpelPdveeeidenveyrplRLeit 105 e+ +e+ k+++++v e + +l + + ++++ +ey++ RLei FUN_002345-T1 154 EKCLEIAKEVSDRVGEGSAYGNLGNTYQSLGDFRKAIEYHEERLEIA 200 5678899999999999999999999999999**************95 PP == domain 2 score: -2.1 bits; conditional E-value: 7.5 REGB_T4 60 yvfellkklkekvkevveflelpelPdveeeidenveyrplRLeit 105 + +e+ ++++++v e + +l + ++++ ++y++ Lei FUN_002345-T1 275 KCLEIATEVSDQVGEGSAYGNLGVAYQSMADFRKAIQYHDKHLEIA 320 5678888889999999999999999999999999999999999996 PP == domain 3 score: -1.6 bits; conditional E-value: 5.5 REGB_T4 62 fellkklkekvkevveflelpelPdveeeidenveyrplRLeit 105 +e+ k+++++v e + +l + + ++++ +ey++ Lei FUN_002345-T1 357 LEIAKEVSDRVGEGSAYGSLGNAYQSLGDFRKAIEYHEKHLEIA 400 56777788888888888888888888889999999999999997 PP == domain 4 score: 0.8 bits; conditional E-value: 0.98 REGB_T4 61 vfellkklkekvkevveflelpelPdveeeidenveyrplRLeit 105 +e+ k+++++v e + +l + + ++++ +ey++ RLei FUN_002345-T1 436 HLEIAKEVSDRVGEGSAYGSLGNAYKSLGNFRKAIEYHEERLEIA 480 46778888888888889999999999899999***********95 PP == domain 5 score: 1.2 bits; conditional E-value: 0.75 REGB_T4 67 klkekvkevveflelpelPdveeeidenveyrplRLeitd 106 ++ ++v e + + +l d ++++ +ey++ RLei FUN_002345-T1 602 EVGNRVGEGNAYGNLGIAYDSLGDFRKAIEYQEKRLEIAK 641 5666666667777777777777889999*********975 PP >> Mre11_C_bact Mre11 C-terminal domain, bacteria # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 1.4 9.8e+02 22 42 .. 107 127 .. 105 132 .. 0.84 2 ? 3.3 0.0 0.17 1.2e+02 22 42 .. 147 167 .. 145 172 .. 0.85 3 ? -1.6 0.0 5.6 4e+03 23 34 .. 228 239 .. 226 243 .. 0.80 4 ? 3.5 0.0 0.14 98 22 43 .. 267 288 .. 265 292 .. 0.85 5 ? 0.3 0.0 1.4 9.8e+02 22 42 .. 347 367 .. 345 372 .. 0.84 6 ? 2.7 0.0 0.25 1.8e+02 22 42 .. 387 407 .. 385 412 .. 0.85 7 ? 2.7 0.0 0.25 1.8e+02 22 42 .. 427 447 .. 425 452 .. 0.85 8 ? -1.6 0.0 5.4 3.8e+03 23 34 .. 508 519 .. 506 524 .. 0.81 9 ? -1.5 0.1 5.1 3.6e+03 23 37 .. 588 602 .. 586 609 .. 0.79 10 ? -2.1 0.0 7.8 5.5e+03 23 43 .. 628 648 .. 626 652 .. 0.79 11 ? 0.2 0.1 1.5 1e+03 23 40 .. 708 725 .. 705 727 .. 0.82 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 1.4 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e h+k L i e+ D v FUN_002345-T1 107 RKAIEYHDKHLEIAKEVSDRV 127 567799**********99988 PP == domain 2 score: 3.3 bits; conditional E-value: 0.17 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002345-T1 147 RKAIEYHEKCLEIAKEVSDRV 167 577799**********99988 PP == domain 3 score: -1.6 bits; conditional E-value: 5.6 Mre11_C_bact 23 kReenhekLLki 34 k e hek L i FUN_002345-T1 228 KAIEYHEKCLEI 239 66799****998 PP == domain 4 score: 3.5 bits; conditional E-value: 0.14 Mre11_C_bact 22 kkReenhekLLkiLDeLLDevk 43 +k e hek L i e+ D v FUN_002345-T1 267 RKAIEYHEKCLEIATEVSDQVG 288 577799***********99985 PP == domain 5 score: 0.3 bits; conditional E-value: 1.4 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e h+k L i e+ D v FUN_002345-T1 347 RKAIEYHDKHLEIAKEVSDRV 367 567799**********99988 PP == domain 6 score: 2.7 bits; conditional E-value: 0.25 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002345-T1 387 RKAIEYHEKHLEIAKEVSDRV 407 577799**********99988 PP == domain 7 score: 2.7 bits; conditional E-value: 0.25 Mre11_C_bact 22 kkReenhekLLkiLDeLLDev 42 +k e hek L i e+ D v FUN_002345-T1 427 RKAIEYHEKHLEIAKEVSDRV 447 577799**********99988 PP == domain 8 score: -1.6 bits; conditional E-value: 5.4 Mre11_C_bact 23 kReenhekLLki 34 k e hek L i FUN_002345-T1 508 KAIEYHEKCLEI 519 66799****998 PP == domain 9 score: -1.5 bits; conditional E-value: 5.1 Mre11_C_bact 23 kReenhekLLkiLDe 37 k e hek L i e FUN_002345-T1 588 KAIEYHEKHLEIAIE 602 66799*****99655 PP == domain 10 score: -2.1 bits; conditional E-value: 7.8 Mre11_C_bact 23 kReenhekLLkiLDeLLDevk 43 k e ek L i e+ D v FUN_002345-T1 628 KAIEYQEKRLEIAKEVSDRVG 648 566888999999999999885 PP == domain 11 score: 0.2 bits; conditional E-value: 1.5 Mre11_C_bact 23 kReenhekLLkiLDeLLD 40 k e hek L i e+ D FUN_002345-T1 708 KAVEYHEKHLEIAKEVGD 725 67799*******998765 PP >> FbpC_C_terminal FbpC C-terminal regulatory nucleotide binding domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 1.4 1e+03 11 25 .. 33 47 .. 29 49 .. 0.91 2 ? 0.5 0.0 1.4 9.8e+02 11 25 .. 73 87 .. 69 91 .. 0.91 3 ? 0.4 0.0 1.5 1.1e+03 11 25 .. 553 567 .. 550 571 .. 0.92 4 ? 0.5 0.0 1.3 9.2e+02 11 25 .. 593 607 .. 590 611 .. 0.91 5 ? 2.0 0.0 0.46 3.2e+02 11 25 .. 673 687 .. 669 690 .. 0.93 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 1.4 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei+++aG +V FUN_002345-T1 33 HEKHLEIAIEAGHRV 47 789*********998 PP == domain 2 score: 0.5 bits; conditional E-value: 1.4 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei++++G +V FUN_002345-T1 73 HQKHFEIAIEVGHRV 87 889**********98 PP == domain 3 score: 0.4 bits; conditional E-value: 1.5 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +++h Ei++++G +V FUN_002345-T1 553 HQKHFEIAIEVGHRV 567 789**********98 PP == domain 4 score: 0.5 bits; conditional E-value: 1.3 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 + +h Ei++++G +V FUN_002345-T1 593 HEKHLEIAIEVGNRV 607 789**********98 PP == domain 5 score: 2.0 bits; conditional E-value: 0.46 FbpC_C_terminal 11 kaRhvEiSlraGqtV 25 +a+h Ei++++G +V FUN_002345-T1 673 HAKHLEIAIEVGHRV 687 89**********998 PP >> TPR_3 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.4 0.056 40 7 23 .. 16 32 .. 12 34 .. 0.91 2 ? 1.1 0.0 0.99 7.1e+02 6 23 .. 135 152 .. 135 155 .. 0.90 3 ? 0.5 0.0 1.5 1.1e+03 8 23 .. 177 192 .. 175 194 .. 0.88 4 ? -1.9 0.2 8.2 5.8e+03 7 24 .. 296 314 .. 295 317 .. 0.84 5 ? 2.2 0.0 0.45 3.2e+02 7 24 .. 336 354 .. 335 358 .. 0.87 6 ? 1.1 0.0 0.99 7.1e+02 6 23 .. 375 392 .. 375 395 .. 0.90 7 ? 0.5 0.0 1.5 1.1e+03 8 23 .. 417 432 .. 415 434 .. 0.88 8 ? 2.1 0.0 0.47 3.3e+02 8 24 .. 537 554 .. 535 555 .. 0.87 9 ? 2.3 0.0 0.4 2.8e+02 6 23 .. 575 592 .. 575 595 .. 0.92 10 ? -0.1 0.1 2.2 1.6e+03 8 23 .. 657 672 .. 655 674 .. 0.87 11 ? 3.6 0.1 0.16 1.1e+02 8 23 .. 697 712 .. 695 715 .. 0.88 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.056 TPR_3 7 lAatfylkgkyqeArel 23 lA++f++ g++ +A+ + FUN_002345-T1 16 LAYAFQSLGNFRKAIKY 32 8*************865 PP == domain 2 score: 1.1 bits; conditional E-value: 0.99 TPR_3 6 slAatfylkgkyqeArel 23 sl+ ++++ g++ +A+e+ FUN_002345-T1 135 SLGNAYQSLGDFRKAIEY 152 67889***********97 PP == domain 3 score: 0.5 bits; conditional E-value: 1.5 TPR_3 8 AatfylkgkyqeArel 23 + t+++ g++ +A+e+ FUN_002345-T1 177 GNTYQSLGDFRKAIEY 192 569***********97 PP == domain 4 score: -1.9 bits; conditional E-value: 8.2 TPR_3 7 lAatfylkgkyqeArel.y 24 l+ +++++ ++ +A+++ + FUN_002345-T1 296 LGVAYQSMADFRKAIQYhD 314 67799*********99866 PP == domain 5 score: 2.2 bits; conditional E-value: 0.45 TPR_3 7 lAatfylkgkyqeArel.y 24 l+ ++++ g++ +A+e+ + FUN_002345-T1 336 LGVAYQSLGDFRKAIEYhD 354 6789***********9966 PP == domain 6 score: 1.1 bits; conditional E-value: 0.99 TPR_3 6 slAatfylkgkyqeArel 23 sl+ ++++ g++ +A+e+ FUN_002345-T1 375 SLGNAYQSLGDFRKAIEY 392 67889***********97 PP == domain 7 score: 0.5 bits; conditional E-value: 1.5 TPR_3 8 AatfylkgkyqeArel 23 + t+++ g++ +A+e+ FUN_002345-T1 417 GNTYQSLGDFRKAIEY 432 569***********97 PP == domain 8 score: 2.1 bits; conditional E-value: 0.47 TPR_3 8 AatfylkgkyqeArel.y 24 + +f++ g++ +A+e+ + FUN_002345-T1 537 GNAFQSLGDFRKAIEYhQ 554 558************977 PP == domain 9 score: 2.3 bits; conditional E-value: 0.4 TPR_3 6 slAatfylkgkyqeArel 23 sl+ ++++ g++ +A+e+ FUN_002345-T1 575 SLGIAYQSLGDFRKAIEY 592 7899************97 PP == domain 10 score: -0.1 bits; conditional E-value: 2.2 TPR_3 8 AatfylkgkyqeArel 23 + ++++ g++ +A+e+ FUN_002345-T1 657 GNAYQSLGDFRKAIEY 672 5589*********997 PP == domain 11 score: 3.6 bits; conditional E-value: 0.16 TPR_3 8 AatfylkgkyqeArel 23 + ++++ g++q+A+e+ FUN_002345-T1 697 GNAYQSLGDFQKAVEY 712 5589**********97 PP >> CaM_bdg_C0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.1 1.9 1.4e+03 11 22 .. 114 125 .. 113 126 .. 0.88 2 ? -0.4 0.0 3 2.1e+03 11 22 .. 154 165 .. 153 166 .. 0.88 3 ? 1.4 0.0 0.79 5.6e+02 11 22 .. 314 325 .. 312 326 .. 0.88 4 ? 0.2 0.1 1.9 1.4e+03 11 22 .. 354 365 .. 353 366 .. 0.88 5 ? 1.5 0.0 0.76 5.4e+02 11 22 .. 394 405 .. 392 406 .. 0.90 6 ? 1.5 0.0 0.76 5.4e+02 11 22 .. 434 445 .. 432 446 .. 0.90 7 ? 4.4 0.1 0.093 66 11 22 .. 634 645 .. 632 646 .. 0.90 8 ? 0.7 0.0 1.3 9.2e+02 11 22 .. 714 725 .. 712 726 .. 0.89 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 1.9 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002345-T1 114 DKHLEIAKEVSD 125 589******998 PP == domain 2 score: -0.4 bits; conditional E-value: 3 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002345-T1 154 EKCLEIAKEVSD 165 788******998 PP == domain 3 score: 1.4 bits; conditional E-value: 0.79 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+AR + D FUN_002345-T1 314 DKHLEIAREVSD 325 699******999 PP == domain 4 score: 0.2 bits; conditional E-value: 1.9 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002345-T1 354 DKHLEIAKEVSD 365 589******998 PP == domain 5 score: 1.5 bits; conditional E-value: 0.76 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002345-T1 394 EKHLEIAKEVSD 405 89*******998 PP == domain 6 score: 1.5 bits; conditional E-value: 0.76 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002345-T1 434 EKHLEIAKEVSD 445 89*******998 PP == domain 7 score: 4.4 bits; conditional E-value: 0.093 CaM_bdg_C0 11 qkklElARhaaD 22 +k+lE+A+ + D FUN_002345-T1 634 EKRLEIAKEVSD 645 8********998 PP == domain 8 score: 0.7 bits; conditional E-value: 1.3 CaM_bdg_C0 11 qkklElARhaaD 22 +k lE+A+ + D FUN_002345-T1 714 EKHLEIAKEVGD 725 89******9988 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1223 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 503 (0.0196907); expected 510.9 (0.02) Passed bias filter: 453 (0.0177334); expected 510.9 (0.02) Passed Vit filter: 61 (0.00238794); expected 25.5 (0.001) Passed Fwd filter: 43 (0.0016833); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 36 [number of targets reported over threshold] # CPU time: 0.57u 0.42s 00:00:00.99 Elapsed: 00:00:00.48 # Mc/sec: 10251.55 // Query: FUN_002346-T1 [L=1479] Description: FUN_002346 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-74 246.1 20.4 1.5e-16 60.8 0.2 5.8 6 TPR_12 Tetratricopeptide repeat 4.3e-74 250.3 0.0 6e-74 249.8 0.0 1.2 1 GT4-conflict Family 4 Glycosyltransferase in conflict sys 5.6e-53 173.0 11.4 1.7e-05 25.0 0.0 10.0 9 TPR_7 Tetratricopeptide repeat 4.5e-50 171.2 0.0 7.7e-50 170.4 0.0 1.3 1 CHAT CHAT domain 2.2e-46 154.3 35.4 9.6e-06 25.7 0.2 10.6 10 TPR_1 Tetratricopeptide repeat 1.1e-34 117.9 7.8 0.00074 19.9 0.0 9.2 9 TPR_10 Tetratricopeptide repeat 7.1e-34 113.5 27.5 0.0001 22.7 0.1 10.4 10 TPR_8 Tetratricopeptide repeat 5.8e-24 82.7 31.2 0.033 14.8 0.3 10.6 11 TPR_2 Tetratricopeptide repeat 6.6e-19 69.1 0.0 1.9e-18 67.6 0.0 1.8 1 Glyco_trans_1_4 Glycosyl transferases group 1 4.1e-18 66.0 0.0 1.2e-17 64.5 0.0 1.7 1 Glycos_transf_1 Glycosyl transferases group 1 2.5e-11 44.0 9.9 2.1 8.9 0.0 7.9 7 Rapsyn_N Rapsyn N-terminal myristoylation and linker 6.5e-11 42.3 8.9 13 7.4 0.0 10.2 10 TPR_14 Tetratricopeptide repeat 2.4e-09 37.4 0.0 0.00022 21.1 0.0 3.3 3 TPR_MalT MalT-like TPR region 9.6e-06 25.8 0.0 2.4e-05 24.5 0.0 1.7 1 TRADD-like_N TRADD-like N-terminal domain 0.00014 22.3 9.4 9.9 7.2 0.1 6.7 5 TPR_17 Tetratricopeptide repeat 0.0014 19.5 7.1 9.8 7.2 0.1 5.9 4 TPR_16 Tetratricopeptide repeat 0.0046 18.0 11.9 1.3e+02 4.1 0.0 8.8 8 TPR_6 Tetratricopeptide repeat 0.007 16.6 8.7 15 5.7 0.1 6.6 6 RPN7 26S proteasome subunit RPN7 0.009 16.0 2.9 19 5.0 0.0 5.9 8 TPR_15 Tetratricopeptide repeat ------ inclusion threshold ------ 0.038 14.7 13.1 50 4.9 0.0 8.4 9 PPR PPR repeat 0.19 11.8 0.1 44 4.2 0.0 4.2 5 SHNi-TPR SHNi-TPR 0.22 12.3 8.7 50 4.7 0.1 6.9 8 GGDEF_2 GGDEF-like domain 0.26 12.0 13.6 83 3.9 0.1 7.5 8 ARM_TT21_4th Tetratricopeptide repeat protein 21 forth AR 0.33 11.3 0.5 0.78 10.1 0.5 1.5 1 UFL1_C E3 UFM1-protein ligase 1 C-terminal domain Domain annotation for each model (and alignments): >> TPR_12 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.7 0.3 1.6e-14 1.7e-11 16 75 .. 687 744 .. 684 746 .. 0.96 2 ! 49.5 0.6 4.7e-16 5e-13 9 77 .] 720 786 .. 720 786 .. 0.98 3 ! 56.9 0.3 2.4e-18 2.5e-15 4 77 .] 755 826 .. 752 826 .. 0.96 4 ! 60.8 0.2 1.4e-19 1.5e-16 4 77 .] 795 866 .. 792 866 .. 0.96 5 ! 55.3 0.1 7.6e-18 8e-15 4 75 .. 875 944 .. 872 946 .. 0.96 6 ! 36.1 0.0 7.3e-12 7.8e-09 4 74 .. 955 1023 .. 952 1026 .. 0.93 Alignments for each domain: == domain 1 score: 44.7 bits; conditional E-value: 1.6e-14 TPR_12 16 lgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 lg+ ++A+e++ek le+a+++ d+ ++ +a+ Lg y+ lgd+++A+e++e+ leia FUN_002346-T1 687 LGDIQKAIEYHEKHLEIAKEV--SDRVGEGRAYESLGNDYQSLGDFRKAIEYHEKRLEIA 744 89*******************..9**********************************98 PP == domain 2 score: 49.5 bits; conditional E-value: 4.7e-16 TPR_12 9 lAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 l++ ++ lg++ +A+e++ek le+a ++ +++ ++ +a+ Lg +y+ lgd+++A+e+ e+ leia++ FUN_002346-T1 720 LGNDYQSLGDFRKAIEYHEKRLEIAIEV--GHRVGEGNAYGSLGNAYQSLGDFRKAIEYQEKHLEIARE 786 799*************************..99**********************************986 PP == domain 3 score: 56.9 bits; conditional E-value: 2.4e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+++++ lg++ +A+e++ek le+a+++ +++ ++ +a+ Lg +y+ lgd+++ +e++e++l+ia++ FUN_002346-T1 755 NAYGSLGNAYQSLGDFRKAIEYQEKHLEIAREV--GHRVGEGNAYGSLGSAYQSLGDFRKSIEYHEKSLKIARE 826 78989****************************..99**********************************986 PP == domain 4 score: 60.8 bits; conditional E-value: 1.4e-19 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleiaek 77 +a+ l+++++ lg++ +++e++ek+l +a+++ +++ ++ +a+ Lg +y+algd+++A+e++e++l+ia++ FUN_002346-T1 795 NAYGSLGSAYQSLGDFRKSIEYHEKSLKIAREV--GHRVGEGNAYGSLGSAYQALGDFRKAIEYHEKSLKIARE 866 78989****************************..99**********************************986 PP == domain 5 score: 55.3 bits; conditional E-value: 7.6e-18 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqaleia 75 +a+ l++ ++ lg++ +A+e++ek le+a ++ d+ ++ a+ Lg +y+ lgd+++A+e++e+ leia FUN_002346-T1 875 NAYGSLGNDYQSLGDFRKAIEYHEKHLEIAIEV--SDRVGEGSAYGSLGNAYQSLGDFKKAIEYHEKRLEIA 944 78989****************************..9**********************************98 PP == domain 6 score: 36.1 bits; conditional E-value: 7.3e-12 TPR_12 4 talnnlAavlrrlgrydeAlellekalelaerllGpdhpltatalrnLgrlylalgdyeeAlelleqalei 74 +a+ nl+++++ lg++ +A+e++e+ l +a ++ +d+ ++ ++++n+g y+ lg++++A + + a+++ FUN_002346-T1 955 NAYGNLGNAYQSLGEFRKAIEYHENFLKIAIEV--GDRAGEGISHHNIGHGYFSLGQFKKACDKFASAVKV 1023 799******************************..99************************8888888776 PP >> GT4-conflict Family 4 Glycosyltransferase in conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 249.8 0.0 5.7e-77 6e-74 4 385 .] 26 400 .. 23 400 .. 0.90 Alignments for each domain: == domain 1 score: 249.8 bits; conditional E-value: 5.7e-77 GT4-conflict 4 atewssakGGistfNreLceaLAaaga.eviclVpea..seeeiadAkaagVrLvkaeaepgvsereslllrrpelpagvepdlviGHgrvtGpaA 96 ew+s+ GG+st+Nre++++LA+ + +v +lVpe ++++ ++A++ +++v+a++ g + l p +g + +viGHg G+ A FUN_002346-T1 26 GSEWNSSAGGLSTLNREFAIHLAQQTNvRVSLLVPEGacNDRDKREAQSFDINVVEAKQHYGYEPLD-WLGFPP---EGHRISVVIGHGVKLGRQA 117 579**********************988*******975688888999999*******9999988888.333333...366679************* PP GT4-conflict 97 kalae.dfypdakrvhfvHmapdelewlkekrdaaeraeerekierelaakAdlvvaVGprLaeearrllseapgepkvleldpgfdveae.eepr 190 +a++ ++++k vh vH+ap++l ++k+ ++++ r+e+++ e+ l++ Adlvva Gp+L + + + l+++++ +++ l+pg+ + + + + FUN_002346-T1 118 QAIKCfPQFRNCKWVHTVHTAPEDLSKYKGYENPTSRGEQKHWDEVGLCKCADLVVALGPKLMKAYFSYLQGCKKGEDIFGLTPGLFDREFgDIVQ 213 **9963458****************************************************************************76555437678 PP GT4-conflict 191 tpp.eggklkvLllGRae..DaelKgldlAaravgrlakesrderveLvvrGapaeeaeelrerlaeiagepalevtvrpytkdraeleadlrras 283 tp+ e++ +kvLl GR + D elKg+d+A++a+++ + ++++++Lv +Gap++ ++e+r+rl + g ++ ++tvr++ ++r+ +++ l + + FUN_002346-T1 214 TPKtENDDFKVLLCGRGDneDFELKGYDIAVKAFADPRL--KGKSYHLVFVGAPDGMQDEVRKRLLNH-GITEEQLTVRKFVQSRSGIKELLCEVD 306 888999**********9989**************88876..5667*********************96.777789********************* PP GT4-conflict 284 lvlmPSraEGFGLvglEAiaagvPvLvsseSGlaelLeeklseeeaerlvvpvtgddeedaeewaraieevlrdleaaferaaelreeLaerltWa 379 l++mPSr EG+GLv+lEA++ag+PvLv+s+SG+a+ +++ +++ ++v+ ++d+ ++wa+aie+v + ++ + lre +++ W+ FUN_002346-T1 307 LAIMPSRCEGYGLVALEALSAGLPVLVGSNSGFASAIRDL---PVGACSIVD-SDDP----AKWAEAIERVCCRHGVCLTEIKMLRECYGKEYVWK 394 **************************************99...235678888.4444....7***************************999**** PP GT4-conflict 380 aaaasL 385 + +++L FUN_002346-T1 395 TQCEAL 400 999876 PP >> TPR_7 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.0 0.0 0.00024 0.26 12 35 .. 687 710 .. 685 711 .. 0.92 2 ! 17.5 0.0 4.1e-06 0.0043 1 35 [. 716 750 .. 716 751 .. 0.91 3 ! 23.1 0.0 6.4e-08 6.8e-05 1 35 [. 756 790 .. 756 791 .. 0.95 4 ! 21.3 0.0 2.4e-07 0.00026 1 35 [. 796 830 .. 796 831 .. 0.95 5 ! 25.0 0.0 1.6e-08 1.7e-05 1 35 [. 836 870 .. 836 871 .. 0.95 6 ! 20.1 0.0 6.2e-07 0.00066 1 35 [. 876 910 .. 876 911 .. 0.92 7 ! 24.9 0.0 1.7e-08 1.8e-05 1 35 [. 916 950 .. 916 951 .. 0.93 8 ! 24.2 0.0 3e-08 3.2e-05 1 36 [] 956 991 .. 956 991 .. 0.95 9 ? 2.2 0.0 0.33 3.5e+02 1 24 [. 996 1019 .. 996 1023 .. 0.89 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00024 TPR_7 12 lGdydeAirlyerlLalakdpedr 35 lGd ++Ai+++e++L++ak+ +dr FUN_002346-T1 687 LGDIQKAIEYHEKHLEIAKEVSDR 710 6999****************9998 PP == domain 2 score: 17.5 bits; conditional E-value: 4.1e-06 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+ +L++ y++lGd+++Ai+++e+ L++a + ++r FUN_002346-T1 716 AYESLGNDYQSLGDFRKAIEYHEKRLEIAIEVGHR 750 67889999********************9888876 PP == domain 3 score: 23.1 bits; conditional E-value: 6.4e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai++ e++L++a++ ++r FUN_002346-T1 756 AYGSLGNAYQSLGDFRKAIEYQEKHLEIAREVGHR 790 7899***************************9987 PP == domain 4 score: 21.3 bits; conditional E-value: 2.4e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++ i+++e+ L +a++ ++r FUN_002346-T1 796 AYGSLGSAYQSLGDFRKSIEYHEKSLKIAREVGHR 830 7899**************************99987 PP == domain 5 score: 25.0 bits; conditional E-value: 1.6e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L +a++ ++r FUN_002346-T1 836 AYGSLGSAYQALGDFRKAIEYHEKSLKIAREVGHR 870 7899**************************99987 PP == domain 6 score: 20.1 bits; conditional E-value: 6.2e-07 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L++ y++lGd+++Ai+++e++L++a + +dr FUN_002346-T1 876 AYGSLGNDYQSLGDFRKAIEYHEKHLEIAIEVSDR 910 67899999********************9988887 PP == domain 7 score: 24.9 bits; conditional E-value: 1.7e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedr 35 a+++L+++y++lGd+++Ai+++e+ L++a + ++r FUN_002346-T1 916 AYGSLGNAYQSLGDFKKAIEYHEKRLEIAIEVGHR 950 7899************************9888876 PP == domain 8 score: 24.2 bits; conditional E-value: 3e-08 TPR_7 1 aLsaLariyrklGdydeAirlyerlLalakdpedre 36 a+++L+++y++lG++++Ai+++e+ L +a + +dr+ FUN_002346-T1 956 AYGNLGNAYQSLGEFRKAIEYHENFLKIAIEVGDRA 991 789**************************9999985 PP == domain 9 score: 2.2 bits; conditional E-value: 0.33 TPR_7 1 aLsaLariyrklGdydeAirlyer 24 +++++++ y +lG++++A++ + FUN_002346-T1 996 SHHNIGHGYFSLGQFKKACDKFAS 1019 589****************99876 PP >> CHAT CHAT domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 170.4 0.0 7.3e-53 7.7e-50 8 291 .] 1203 1465 .. 1198 1465 .. 0.88 Alignments for each domain: == domain 1 score: 170.4 bits; conditional E-value: 7.3e-53 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 8 yqallapleaeldqqsirrLvivpdgaLnllPfealvdpdgsryLleryaisylpsara...lsrlrrsaasarrapqlvvgnpdfdraallsk 98 y+a++ p+e+ l +++ +Lviv d+aL +P++a ++ + i ++ps+++ +s++++ ++ a l+vgnp+ + k FUN_002346-T1 1203 YDAVIGPIEDLL-GPEDDELVIVSDDALCFIPWAAVIESIR---------IRIVPSLESyqlISSVPKGYHKKTGA--LLVGNPCLEQ----LK 1280 899****99997.77777*****************988864.........55555544311155565555555555..******9774....35 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxx RF CHAT 99 lvfselpateaEaaalaellaagelkvllgedateealkealkqqyrvvHlatHgvflenppersglvLaaensr.......edglLtaeelae 185 + lp +++E++++a++l+ +l+g++at+ ++++ + ++++++H+a+Hg + + ++L++ n + ed L++++++ FUN_002346-T1 1281 NPLHALPCAQKEVEMIAAILKN---TPLVGKQATKAEVMKRM-SSVGLIHIAAHGDVV-----TGQIALSP-NPGwtqfpkeEDYILKMSDVQA 1364 55699***************77...8***************9.***************.....89999975.4445889999************ PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF CHAT 186 lnlsgaelVvLsACqtalgevsdgdgvlgLaralllaGapsviaslwpVddratarLmkafyenllagkskaeALrqaqlallkdkrddeprhs 279 nl+ a+lVvLs C ++ g++ +g+gv g+ara+l aGa+sv++ lw +dd+at ++mk+fy++l+ gk++++A++q + +l+++++ +++ FUN_002346-T1 1365 ANLR-ARLVVLSCCHSGQGRILKGEGVVGIARAFLAAGARSVLVALWAIDDEATMEFMKRFYQQLKEGKTASAAVHQSMKSLRESEE----FSE 1453 ****.********************************************************************************98....556 PP xxxxxxxxxxxx RF CHAT 280 pyyWAafvliGd 291 +yWA f+liGd FUN_002346-T1 1454 MWYWAPFQLIGD 1465 ***********7 PP >> TPR_1 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 1.8 1.9e+03 13 24 .. 112 123 .. 111 123 .. 0.93 2 ! 8.5 0.1 0.0023 2.5 14 31 .. 687 704 .. 685 706 .. 0.91 3 ! 16.7 0.2 6.4e-06 0.0068 2 26 .. 715 739 .. 714 744 .. 0.89 4 ! 22.1 0.3 1.2e-07 0.00013 2 31 .. 755 784 .. 754 786 .. 0.91 5 ! 21.8 0.0 1.6e-07 0.00017 2 31 .. 795 824 .. 794 826 .. 0.94 6 ! 25.7 0.2 9e-09 9.6e-06 2 31 .. 835 864 .. 834 866 .. 0.94 7 ! 23.2 0.2 5.5e-08 5.8e-05 2 30 .. 875 903 .. 874 904 .. 0.95 8 ! 23.5 0.2 4.5e-08 4.7e-05 3 26 .. 916 939 .. 914 944 .. 0.91 9 ! 23.4 0.7 4.7e-08 5.1e-05 2 25 .. 955 978 .. 954 984 .. 0.90 10 ! 7.3 0.0 0.006 6.4 4 20 .. 997 1013 .. 995 1015 .. 0.93 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 1.8 TPR_1 13 klgkydeAleyy 24 klg+ +A++++ FUN_002346-T1 112 KLGRQAQAIKCF 123 79999******8 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0023 TPR_1 14 lgkydeAleyyekALeln 31 lg+ ++A+ey ek Le+ FUN_002346-T1 687 LGDIQKAIEYHEKHLEIA 704 8***************96 PP == domain 3 score: 16.7 bits; conditional E-value: 6.4e-06 TPR_1 2 kalynlGnayfklgkydeAleyyek 26 +a+ lGn y++lg++ +A+ey ek FUN_002346-T1 715 RAYESLGNDYQSLGDFRKAIEYHEK 739 68899*****************998 PP == domain 4 score: 22.1 bits; conditional E-value: 1.2e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lGnay++lg++ +A+ey ek Le+ FUN_002346-T1 755 NAYGSLGNAYQSLGDFRKAIEYQEKHLEIA 784 59********************99999986 PP == domain 5 score: 21.8 bits; conditional E-value: 1.6e-07 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lG ay++lg++ + +ey ek L++ FUN_002346-T1 795 NAYGSLGSAYQSLGDFRKSIEYHEKSLKIA 824 59**************************97 PP == domain 6 score: 25.7 bits; conditional E-value: 9e-09 TPR_1 2 kalynlGnayfklgkydeAleyyekALeln 31 +a+ lG ay++lg++ +A+ey ek L++ FUN_002346-T1 835 NAYGSLGSAYQALGDFRKAIEYHEKSLKIA 864 59**************************97 PP == domain 7 score: 23.2 bits; conditional E-value: 5.5e-08 TPR_1 2 kalynlGnayfklgkydeAleyyekALel 30 +a+ lGn y++lg++ +A+ey ek Le+ FUN_002346-T1 875 NAYGSLGNDYQSLGDFRKAIEYHEKHLEI 903 59*************************98 PP == domain 8 score: 23.5 bits; conditional E-value: 4.5e-08 TPR_1 3 alynlGnayfklgkydeAleyyek 26 a+ lGnay++lg++++A+ey ek FUN_002346-T1 916 AYGSLGNAYQSLGDFKKAIEYHEK 939 89*******************998 PP == domain 9 score: 23.4 bits; conditional E-value: 4.7e-08 TPR_1 2 kalynlGnayfklgkydeAleyye 25 +a+ nlGnay++lg++ +A+ey e FUN_002346-T1 955 NAYGNLGNAYQSLGEFRKAIEYHE 978 69********************87 PP == domain 10 score: 7.3 bits; conditional E-value: 0.006 TPR_1 4 lynlGnayfklgkydeA 20 + n+G+ yf+lg++++A FUN_002346-T1 997 HHNIGHGYFSLGQFKKA 1013 88**************9 PP >> TPR_10 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.3 0.0 0.52 5.5e+02 14 35 .. 686 707 .. 684 710 .. 0.89 2 ! 12.0 0.0 0.00022 0.24 4 34 .. 716 746 .. 714 747 .. 0.89 3 ! 17.3 0.1 4.5e-06 0.0048 4 35 .. 756 787 .. 754 787 .. 0.95 4 ! 17.5 0.0 4.2e-06 0.0044 4 35 .. 796 827 .. 794 827 .. 0.95 5 ! 19.9 0.0 6.9e-07 0.00074 4 35 .. 836 867 .. 834 867 .. 0.95 6 ! 13.5 0.0 7.4e-05 0.078 4 35 .. 876 907 .. 874 910 .. 0.91 7 ! 15.0 0.0 2.4e-05 0.026 3 34 .. 915 946 .. 914 947 .. 0.91 8 ! 15.7 0.0 1.4e-05 0.015 4 34 .. 956 986 .. 954 987 .. 0.88 9 ? -1.1 0.0 2.9 3.1e+03 6 21 .. 998 1013 .. 998 1021 .. 0.91 Alignments for each domain: == domain 1 score: 1.3 bits; conditional E-value: 0.52 TPR_10 14 aqgryeeAeelleealairerv 35 +g+ + A e++e+ l+i+++v FUN_002346-T1 686 TLGDIQKAIEYHEKHLEIAKEV 707 58999*************9998 PP == domain 2 score: 12.0 bits; conditional E-value: 0.00022 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ L+n ++++g++ A e++e+ l+i+ + FUN_002346-T1 716 AYESLGNDYQSLGDFRKAIEYHEKRLEIAIE 746 7999*******************98888766 PP == domain 3 score: 17.3 bits; conditional E-value: 4.5e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+na++++g++ A e++e+ l+i+++v FUN_002346-T1 756 AYGSLGNAYQSLGDFRKAIEYQEKHLEIAREV 787 7999*************************997 PP == domain 4 score: 17.5 bits; conditional E-value: 4.2e-06 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+ a++++g++ + e++e++l+i+++v FUN_002346-T1 796 AYGSLGSAYQSLGDFRKSIEYHEKSLKIAREV 827 7999**************************97 PP == domain 5 score: 19.9 bits; conditional E-value: 6.9e-07 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+ a++a+g++ A e++e++l+i+++v FUN_002346-T1 836 AYGSLGSAYQALGDFRKAIEYHEKSLKIAREV 867 7999**************************97 PP == domain 6 score: 13.5 bits; conditional E-value: 7.4e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairerv 35 ++ L+n ++++g++ A e++e+ l+i+ +v FUN_002346-T1 876 AYGSLGNDYQSLGDFRKAIEYHEKHLEIAIEV 907 7999********************99998876 PP == domain 7 score: 15.0 bits; conditional E-value: 2.4e-05 TPR_10 3 sslnnLanalraqgryeeAeelleealairer 34 s++ L+na++++g+++ A e++e+ l+i+ + FUN_002346-T1 915 SAYGSLGNAYQSLGDFKKAIEYHEKRLEIAIE 946 6899********************98888766 PP == domain 8 score: 15.7 bits; conditional E-value: 1.4e-05 TPR_10 4 slnnLanalraqgryeeAeelleealairer 34 ++ nL+na++++g++ A e++e l+i+ + FUN_002346-T1 956 AYGNLGNAYQSLGEFRKAIEYHENFLKIAIE 986 89********************987777665 PP == domain 9 score: -1.1 bits; conditional E-value: 2.9 TPR_10 6 nnLanalraqgryeeA 21 +n++ ++++g+++ A FUN_002346-T1 998 HNIGHGYFSLGQFKKA 1013 799*********9987 PP >> TPR_8 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 3.6 3.8e+03 13 24 .. 112 123 .. 111 123 .. 0.92 2 ? 3.6 0.0 0.13 1.3e+02 13 32 .. 686 705 .. 685 706 .. 0.87 3 ! 9.0 0.1 0.0023 2.5 2 30 .. 715 743 .. 714 744 .. 0.86 4 ! 22.7 0.1 9.5e-08 0.0001 3 32 .. 756 785 .. 754 787 .. 0.93 5 ! 20.2 0.0 6.1e-07 0.00065 3 32 .. 796 825 .. 794 827 .. 0.94 6 ! 21.6 0.1 2.1e-07 0.00022 3 32 .. 836 865 .. 834 867 .. 0.94 7 ! 9.4 0.1 0.0017 1.8 3 30 .. 876 903 .. 874 904 .. 0.88 8 ! 18.0 0.2 3e-06 0.0032 2 30 .. 915 943 .. 914 944 .. 0.88 9 ! 16.1 0.2 1.2e-05 0.013 3 29 .. 956 982 .. 954 984 .. 0.87 10 ? 4.2 0.0 0.082 87 4 21 .. 997 1014 .. 996 1025 .. 0.80 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 3.6 TPR_8 13 klgdyeeAkeyy 24 klg+ ++A++++ FUN_002346-T1 112 KLGRQAQAIKCF 123 89********98 PP == domain 2 score: 3.6 bits; conditional E-value: 0.13 TPR_8 13 klgdyeeAkeyyekaleldp 32 +lgd+++A+ey ek le+++ FUN_002346-T1 686 TLGDIQKAIEYHEKHLEIAK 705 69*********999988875 PP == domain 3 score: 9.0 bits; conditional E-value: 0.0023 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG+ y++lgd+ +A+ey ek le+ FUN_002346-T1 715 RAYESLGNDYQSLGDFRKAIEYHEKRLEI 743 789999999*************8886665 PP == domain 4 score: 22.7 bits; conditional E-value: 9.5e-08 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +A+ey ek le+++ FUN_002346-T1 756 AYGSLGNAYQSLGDFRKAIEYQEKHLEIAR 785 89**********************999987 PP == domain 5 score: 20.2 bits; conditional E-value: 6.1e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y++lgd+ +++ey ek+l++++ FUN_002346-T1 796 AYGSLGSAYQSLGDFRKSIEYHEKSLKIAR 825 89**************************97 PP == domain 6 score: 21.6 bits; conditional E-value: 2.1e-07 TPR_8 3 ayynlGliylklgdyeeAkeyyekaleldp 32 ay lG++y+ lgd+ +A+ey ek+l++++ FUN_002346-T1 836 AYGSLGSAYQALGDFRKAIEYHEKSLKIAR 865 89**************************97 PP == domain 7 score: 9.4 bits; conditional E-value: 0.0017 TPR_8 3 ayynlGliylklgdyeeAkeyyekalel 30 ay lG+ y++lgd+ +A+ey ek le+ FUN_002346-T1 876 AYGSLGNDYQSLGDFRKAIEYHEKHLEI 903 89999999*************9887776 PP == domain 8 score: 18.0 bits; conditional E-value: 3e-06 TPR_8 2 eayynlGliylklgdyeeAkeyyekalel 30 +ay lG++y++lgd+++A+ey ek le+ FUN_002346-T1 915 SAYGSLGNAYQSLGDFKKAIEYHEKRLEI 943 589*******************8886665 PP == domain 9 score: 16.1 bits; conditional E-value: 1.2e-05 TPR_8 3 ayynlGliylklgdyeeAkeyyekale 29 ay nlG++y++lg++ +A+ey e l+ FUN_002346-T1 956 AYGNLGNAYQSLGEFRKAIEYHENFLK 982 9*******************9766665 PP == domain 10 score: 4.2 bits; conditional E-value: 0.082 TPR_8 4 yynlGliylklgdyeeAk 21 ++n+G+ y +lg++++A FUN_002346-T1 997 HHNIGHGYFSLGQFKKAC 1014 689999999999999996 PP >> TPR_2 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 3.2 3.4e+03 13 24 .. 112 123 .. 111 123 .. 0.93 2 ? -1.3 0.0 4.6 4.9e+03 14 23 .. 687 696 .. 686 704 .. 0.86 3 ! 9.8 0.2 0.0012 1.3 2 23 .. 715 736 .. 714 741 .. 0.91 4 ! 14.1 0.3 5.1e-05 0.054 3 30 .. 756 783 .. 754 786 .. 0.86 5 ! 10.4 0.0 0.00081 0.86 3 31 .. 796 824 .. 794 826 .. 0.91 6 ! 14.8 0.3 3.1e-05 0.033 3 31 .. 836 864 .. 834 866 .. 0.91 7 ! 9.1 0.1 0.002 2.2 3 23 .. 876 896 .. 874 903 .. 0.90 8 ! 12.4 0.2 0.00018 0.19 3 23 .. 916 936 .. 914 942 .. 0.92 9 ! 13.4 0.4 8.8e-05 0.094 3 23 .. 956 976 .. 954 984 .. 0.87 10 ! 11.5 0.0 0.00036 0.38 4 30 .. 997 1023 .. 995 1026 .. 0.91 11 ? -0.9 0.0 3.2 3.4e+03 10 26 .. 1055 1071 .. 1054 1074 .. 0.84 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 3.2 TPR_2 13 klgdyeeAleay 24 klg+ ++A++++ FUN_002346-T1 112 KLGRQAQAIKCF 123 79*********8 PP == domain 2 score: -1.3 bits; conditional E-value: 4.6 TPR_2 14 lgdyeeAlea 23 lgd ++A+e+ FUN_002346-T1 687 LGDIQKAIEY 696 79999**998 PP == domain 3 score: 9.8 bits; conditional E-value: 0.0012 TPR_2 2 ealynlGlayyklgdyeeAlea 23 +a+ lG+ y lgd+ +A+e+ FUN_002346-T1 715 RAYESLGNDYQSLGDFRKAIEY 736 58899***************98 PP == domain 4 score: 14.1 bits; conditional E-value: 5.1e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAlel 30 a+ lG+ay lgd+ +A+e+ ek le+ FUN_002346-T1 756 AYGSLGNAYQSLGDFRKAIEYQEKHLEI 783 7888*****************9986655 PP == domain 5 score: 10.4 bits; conditional E-value: 0.00081 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ lG ay lgd+ + +e+ ek+l+++ FUN_002346-T1 796 AYGSLGSAYQSLGDFRKSIEYHEKSLKIA 824 7888**********************997 PP == domain 6 score: 14.8 bits; conditional E-value: 3.1e-05 TPR_2 3 alynlGlayyklgdyeeAleayekAleld 31 a+ lG ay +lgd+ +A+e+ ek+l+++ FUN_002346-T1 836 AYGSLGSAYQALGDFRKAIEYHEKSLKIA 864 7888**********************997 PP == domain 7 score: 9.1 bits; conditional E-value: 0.002 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ y lgd+ +A+e+ FUN_002346-T1 876 AYGSLGNDYQSLGDFRKAIEY 896 78889**************98 PP == domain 8 score: 12.4 bits; conditional E-value: 0.00018 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ lG+ay lgd+++A+e+ FUN_002346-T1 916 AYGSLGNAYQSLGDFKKAIEY 936 6778***************98 PP == domain 9 score: 13.4 bits; conditional E-value: 8.8e-05 TPR_2 3 alynlGlayyklgdyeeAlea 23 a+ nlG+ay lg++ +A+e+ FUN_002346-T1 956 AYGNLGNAYQSLGEFRKAIEY 976 899*****************9 PP == domain 10 score: 11.5 bits; conditional E-value: 0.00036 TPR_2 4 lynlGlayyklgdyeeAleayekAlel 30 ++n G y+ lg++++A + + A++ FUN_002346-T1 997 HHNIGHGYFSLGQFKKACDKFASAVKV 1023 89*******************999875 PP == domain 11 score: -0.9 bits; conditional E-value: 3.2 TPR_2 10 ayyklgdyeeAleayek 26 ++++ g+ +eAl a ++ FUN_002346-T1 1055 SLLRIGKIDEALFAADE 1071 67899*******98776 PP >> Glyco_trans_1_4 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.6 0.0 1.8e-21 1.9e-18 3 138 .. 223 369 .. 221 371 .. 0.84 Alignments for each domain: == domain 1 score: 67.6 bits; conditional E-value: 1.8e-21 Glyco_trans_1_4 3 vilfvGrl.ae..nekgvdllleav..plvrkkerdvrlvivGdgpeeeeeleelak..gledr.veftGfv...edlaellaaadvfvlPsls 85 ++l +Gr +e + kg d+ ++a+ p+++ k +lv+vG + +++e+++++ g++++ ++ fv + ++ell + d++++Ps+ FUN_002346-T1 223 KVLLCGRGdNEdfELKGYDIAVKAFadPRLKGK--SYHLVFVGAPDGMQDEVRKRLLnhGITEEqLTVRKFVqsrSGIKELLCEVDLAIMPSRC 314 678888886667899**********77777766..49******5443556888766448888666*******76444***************** PP Glyco_trans_1_4 86 egfglkllEAmaaglPvVatdvggipevvedgeng..llvppgdpealaeailrl 138 eg+gl++lEA++aglPv + + +g++ +++d g +v+++dp+++aeai+r+ FUN_002346-T1 315 EGYGLVALEALSAGLPVLVGSNSGFASAIRDLPVGacSIVDSDDPAKWAEAIERV 369 *****************999999*******9977766799999*********986 PP >> Glycos_transf_1 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.5 0.0 1.1e-20 1.2e-17 26 155 .. 236 369 .. 210 371 .. 0.82 Alignments for each domain: == domain 1 score: 64.5 bits; conditional E-value: 1.1e-20 Glycos_transf_1 26 keKgldlllkafaklkeklkpdlklviaG..dgeeekklkklaeklgl.ednvkflgfvs.dedlpellkiadvfvlpsrsEgfGivllEAmaa 115 + Kg+d ++kafa+ + k + ++lv++G dg + ++++k+ +++g+ e+++++ +fv ++ ++ell d++++psr Eg G+v+lEA++a FUN_002346-T1 236 ELKGYDIAVKAFADPRLK-GKSYHLVFVGapDGMQ-DEVRKRLLNHGItEEQLTVRKFVQsRSGIKELLCEVDLAIMPSRCEGYGLVALEALSA 327 34***********98776.**********966555.555555566666267788889998899******************************* PP Glycos_transf_1 116 glpviasdvgglrevvkdgetGl..lvkpnnaealaeaiekl 155 glpv++ ++g+++ ++d G +v++ ++ ++aeaie++ FUN_002346-T1 328 GLPVLVGSNSGFASAIRDLPVGAcsIVDSDDPAKWAEAIERV 369 ********************7752268888*********986 PP >> Rapsyn_N Rapsyn N-terminal myristoylation and linker region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.5 0.0 0.047 50 32 76 .. 703 747 .. 687 750 .. 0.81 2 ! 8.9 0.0 0.002 2.1 46 76 .. 757 787 .. 749 790 .. 0.90 3 ? 6.6 0.0 0.011 12 46 76 .. 797 827 .. 788 831 .. 0.89 4 ! 7.6 0.0 0.0052 5.6 46 76 .. 837 867 .. 829 870 .. 0.88 5 ? 3.8 0.0 0.083 89 47 78 .. 878 909 .. 869 911 .. 0.85 6 ! 7.1 0.0 0.0075 7.9 37 76 .. 908 947 .. 904 950 .. 0.87 7 ? 4.9 0.0 0.036 39 46 77 .. 957 988 .. 947 990 .. 0.87 Alignments for each domain: == domain 1 score: 4.5 bits; conditional E-value: 0.047 Rapsyn_N 32 vlkktsdredkfrllGylitahsemGkykealefslaqlniaeel 76 + k+ sdr + r l + + +G ++ a+e+ ++l+ia e+ FUN_002346-T1 703 IAKEVSDRVGEGRAYESLGNDYQSLGDFRKAIEYHEKRLEIAIEV 747 457788888888888888888999*****************9886 PP == domain 2 score: 8.9 bits; conditional E-value: 0.002 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l +a+ +G ++ a+e+ + l+ia+e+ FUN_002346-T1 757 YGSLGNAYQSLGDFRKAIEYQEKHLEIAREV 787 688999***********************97 PP == domain 3 score: 6.6 bits; conditional E-value: 0.011 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G ++ +e+ + l ia+e+ FUN_002346-T1 797 YGSLGSAYQSLGDFRKSIEYHEKSLKIAREV 827 6889999**********************97 PP == domain 4 score: 7.6 bits; conditional E-value: 0.0052 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeel 76 G l a+ +G ++ a+e+ + l ia+e+ FUN_002346-T1 837 YGSLGSAYQALGDFRKAIEYHEKSLKIAREV 867 5788889999*******************97 PP == domain 5 score: 3.8 bits; conditional E-value: 0.083 Rapsyn_N 47 GylitahsemGkykealefslaqlniaeeled 78 G l + + +G ++ a+e+ + l+ia e+ d FUN_002346-T1 878 GSLGNDYQSLGDFRKAIEYHEKHLEIAIEVSD 909 6666777899*****************99876 PP == domain 6 score: 7.1 bits; conditional E-value: 0.0075 Rapsyn_N 37 sdredkfrllGylitahsemGkykealefslaqlniaeel 76 sdr + G l +a+ +G +k a+e+ ++l+ia e+ FUN_002346-T1 908 SDRVGEGSAYGSLGNAYQSLGDFKKAIEYHEKRLEIAIEV 947 56666667789999**********************9886 PP == domain 7 score: 4.9 bits; conditional E-value: 0.036 Rapsyn_N 46 lGylitahsemGkykealefslaqlniaeele 77 G l +a+ +G ++ a+e+ + l ia e+ FUN_002346-T1 957 YGNLGNAYQSLGEFRKAIEYHENFLKIAIEVG 988 688999********************999876 PP >> TPR_14 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 5.4 5.8e+03 13 30 .. 686 703 .. 684 708 .. 0.85 2 ? 4.1 0.1 0.13 1.4e+02 3 29 .. 716 742 .. 714 744 .. 0.88 3 ? 2.8 0.0 0.37 4e+02 5 23 .. 758 776 .. 755 785 .. 0.85 4 ? 0.9 0.0 1.5 1.6e+03 6 30 .. 799 823 .. 795 827 .. 0.85 5 ? 7.4 0.0 0.012 13 6 30 .. 839 863 .. 835 867 .. 0.86 6 ? 2.3 0.0 0.51 5.4e+02 6 29 .. 879 902 .. 875 904 .. 0.84 7 ? 7.0 0.0 0.015 16 6 29 .. 919 942 .. 915 944 .. 0.88 8 ? 4.8 0.0 0.079 84 6 29 .. 959 982 .. 955 986 .. 0.87 9 ? 0.9 0.0 1.5 1.6e+03 11 32 .. 1004 1025 .. 998 1033 .. 0.75 10 ? 3.2 0.1 0.27 2.9e+02 10 41 .. 1055 1087 .. 1052 1089 .. 0.75 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 5.4 TPR_14 13 alGdpdeAlelleralal 30 lGd ++A+e+ e+ l+ FUN_002346-T1 686 TLGDIQKAIEYHEKHLEI 703 58*********9998876 PP == domain 2 score: 4.1 bits; conditional E-value: 0.13 TPR_14 3 awlalarallalGdpdeAlellerala 29 a+ l++ + lGd+ +A+e+ e+ l+ FUN_002346-T1 716 AYESLGNDYQSLGDFRKAIEYHEKRLE 742 77889999*************999887 PP == domain 3 score: 2.8 bits; conditional E-value: 0.37 TPR_14 5 lalarallalGdpdeAlel 23 l++a+ lGd+ +A+e+ FUN_002346-T1 758 GSLGNAYQSLGDFRKAIEY 776 5799*************97 PP == domain 4 score: 0.9 bits; conditional E-value: 1.5 TPR_14 6 alarallalGdpdeAlelleralal 30 l+ a+ lGd+ + +e+ e+ l+ FUN_002346-T1 799 SLGSAYQSLGDFRKSIEYHEKSLKI 823 6999**************9998875 PP == domain 5 score: 7.4 bits; conditional E-value: 0.012 TPR_14 6 alarallalGdpdeAlelleralal 30 l+ a+ alGd+ +A+e+ e+ l+ FUN_002346-T1 839 SLGSAYQALGDFRKAIEYHEKSLKI 863 6999**************9998875 PP == domain 6 score: 2.3 bits; conditional E-value: 0.51 TPR_14 6 alarallalGdpdeAlellerala 29 l++ + lGd+ +A+e+ e+ l+ FUN_002346-T1 879 SLGNDYQSLGDFRKAIEYHEKHLE 902 67888999**********998876 PP == domain 7 score: 7.0 bits; conditional E-value: 0.015 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lGd+++A+e+ e+ l+ FUN_002346-T1 919 SLGNAYQSLGDFKKAIEYHEKRLE 942 699***************999887 PP == domain 8 score: 4.8 bits; conditional E-value: 0.079 TPR_14 6 alarallalGdpdeAlellerala 29 l++a+ lG++ +A+e+ e l+ FUN_002346-T1 959 NLGNAYQSLGEFRKAIEYHENFLK 982 689***************999887 PP == domain 9 score: 0.9 bits; conditional E-value: 1.5 TPR_14 11 llalGdpdeAlelleralaldP 32 ++ lG++++A + + +a++ + FUN_002346-T1 1004 YFSLGQFKKACDKFASAVKVFN 1025 7778888888888888887665 PP == domain 10 score: 3.2 bits; conditional E-value: 0.27 TPR_14 10 allalGdpdeAlelleralal.dPddpeawlal 41 ll+ G+ deAl +++++ a+ d+ +++++l FUN_002346-T1 1055 SLLRIGKIDEALFAADEGRAQtLSDNLWIQYKL 1087 6899**************776234555555555 PP >> TPR_MalT MalT-like TPR region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 2.1e-07 0.00022 13 192 .. 686 865 .. 683 866 .. 0.89 2 ! 11.4 0.0 0.00019 0.2 42 116 .. 796 870 .. 789 903 .. 0.61 3 ! 9.9 0.0 0.00051 0.55 14 114 .. 887 988 .. 884 1025 .. 0.87 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 2.1e-07 TPR_MalT 13 sqgeaeeaeelAreALallpe.ddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqal 107 + g++++a+e+ ++ L++ +e +d + a+ +lG ++ +gd+ +A + ++ ++a + ++ a+ ++++ ++ G++++A+e +++ l FUN_002346-T1 686 TLGDIQKAIEYHEKHLEIAKEvSDRVGEGRAYESLGNDYQSLGDFRKAIEYHEKRLEIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAIEYQEKHL 781 67999999999999999998734444558999****************9999999999999999999999************************** PP TPR_MalT 108 qlaqesklealplvgfllvgladLlyEwndLeeAeqhlqqgiqlgrql.epaaaleayvllarvalaqGeleeAetllqraerlar 192 + a+e + + g ++ +l+ + +d+ + ++ +++++++r++ + +ay l + +a G+ + A ++ ++ ++ar FUN_002346-T1 782 EIAREVGHRV--GEGNAYGSLGSAYQSLGDFRKSIEYHEKSLKIAREVgHRVGEGNAYGSLGSAYQALGDFRKAIEYHEKSLKIAR 865 ****999885..8899999****************************9677999999*99*9999****99999999888777665 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00019 TPR_MalT 42 atlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalqlaqeskle 116 a+ +lG a++ +gd+ ++ + ++ ++ar+ ++ a+ +++ ++a G++++A+e ++ l+ a+e + + FUN_002346-T1 796 AYGSLGSAYQSLGDFRKSIEYHEKSLKIAREVGHRVGEGNAYGSLGSAYQALGDFRKAIEYHEKSLKIAREVGHR 870 566677777777777777777777777777777777777777777777777777777777777777777765544 PP == domain 3 score: 9.9 bits; conditional E-value: 0.00051 TPR_MalT 14 qgeaeeaeelAreALal.lpeddllartlatlvlGeasllqgdlesAlaalreaealarradslhvtllallqqaellraqGqLhqAaetyqqalq 108 g++ +a+e+ ++ L++ ++ +d ++a+ +lG a++ +gd+++A + ++ ++a + ++ a+ +++ ++ G++++A+e + l+ FUN_002346-T1 887 LGDFRKAIEYHEKHLEIaIEVSDRVGEGSAYGSLGNAYQSLGDFKKAIEYHEKRLEIAIEVGHRVGEGNAYGNLGNAYQSLGEFRKAIEYHENFLK 982 6888899999999998734556666678999**********************99999999999999****************************9 PP TPR_MalT 109 laqesk 114 a e + FUN_002346-T1 983 IAIEVG 988 998765 PP >> TRADD-like_N TRADD-like N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 0.0 2.3e-08 2.4e-05 27 66 .. 527 566 .. 525 567 .. 0.94 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 2.3e-08 TRADD-like_N 27 eGSilvtfkgsreeilerllalynsGeLrellglsvetek 66 eGSi+v ++++ ++ le ++++y+sG L++l+ + ++t+ FUN_002346-T1 527 EGSIVVSLRCPTLASLEHIWSDYRSGDLDKLAERYLVTDD 566 7******************************999998886 PP >> TPR_17 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.2 0.1 0.04 43 14 34 .] 755 775 .. 753 775 .. 0.92 2 ? 0.7 0.0 1.1 1.2e+03 14 33 .. 795 814 .. 793 815 .. 0.87 3 ? 3.6 0.1 0.14 1.5e+02 14 34 .] 835 855 .. 833 855 .. 0.92 4 ? 4.9 0.0 0.053 56 15 34 .] 916 935 .. 913 935 .. 0.91 5 ! 7.2 0.1 0.0093 9.9 14 34 .] 955 975 .. 953 975 .. 0.92 Alignments for each domain: == domain 1 score: 5.2 bits; conditional E-value: 0.04 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+++++ +G++ +A++ FUN_002346-T1 755 NAYGSLGNAYQSLGDFRKAIE 775 79****************985 PP == domain 2 score: 0.7 bits; conditional E-value: 1.1 TPR_17 14 dayynLArlllnnGqleeAl 33 +ay L+ +++ +G++ + + FUN_002346-T1 795 NAYGSLGSAYQSLGDFRKSI 814 799***********998766 PP == domain 3 score: 3.6 bits; conditional E-value: 0.14 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay L+ +++ +G++ +A++ FUN_002346-T1 835 NAYGSLGSAYQALGDFRKAIE 855 79****************985 PP == domain 4 score: 4.9 bits; conditional E-value: 0.053 TPR_17 15 ayynLArlllnnGqleeAlq 34 ay L+++++ +G++ +A++ FUN_002346-T1 916 AYGSLGNAYQSLGDFKKAIE 935 899**************985 PP == domain 5 score: 7.2 bits; conditional E-value: 0.0093 TPR_17 14 dayynLArlllnnGqleeAlq 34 +ay nL+++++ +G++ +A++ FUN_002346-T1 955 NAYGNLGNAYQSLGEFRKAIE 975 79***************9985 PP >> TPR_16 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.1 0.0092 9.8 3 60 .. 720 783 .. 719 786 .. 0.85 2 ? 2.3 0.1 0.32 3.4e+02 3 19 .. 840 856 .. 833 862 .. 0.85 3 ? 6.1 0.0 0.021 22 3 53 .. 880 936 .. 879 946 .. 0.82 4 ? 1.5 0.0 0.56 6e+02 3 24 .. 960 981 .. 953 982 .. 0.84 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0092 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaayraalra 60 l++++ +gd++ A+++ le a++ + A+ lG a+ +g++ +A+++ ++ l++ FUN_002346-T1 720 LGNDYQSLGDFRKAIEYhekrLEIAIEVGhrVGEGNAYGSLGNAYQSLGDFRKAIEYQEKHLEI 783 799999999999998643333999999999977899*******************999998876 PP == domain 2 score: 2.3 bits; conditional E-value: 0.32 TPR_16 3 laraalaagdyddAaaa 19 l+ a+ a+gd++ A+++ FUN_002346-T1 840 LGSAYQALGDFRKAIEY 856 68999999999999986 PP == domain 3 score: 6.1 bits; conditional E-value: 0.021 TPR_16 3 laraalaagdyddAaaa....leaalrrn..PeaaaAllglGlallrqgrlaeAaaa 53 l++++ +gd++ A+++ le a++ A+ lG a+ +g++ +A+++ FUN_002346-T1 880 LGNDYQSLGDFRKAIEYhekhLEIAIEVSdrVGEGSAYGSLGNAYQSLGDFKKAIEY 936 79999999******87544448888888899778999***************99965 PP == domain 4 score: 1.5 bits; conditional E-value: 0.56 TPR_16 3 laraalaagdyddAaaaleaal 24 l++a+ +g+++ A+++ e++l FUN_002346-T1 960 LGNAYQSLGEFRKAIEYHENFL 981 7999999999999999866666 PP >> TPR_6 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 1.2 1.3e+03 7 29 .. 714 736 .. 713 739 .. 0.72 2 ? 2.4 0.0 0.41 4.3e+02 6 22 .. 760 776 .. 759 776 .. 0.92 3 ? -0.7 0.0 4 4.3e+03 6 22 .. 800 816 .. 799 819 .. 0.89 4 ? 4.1 0.0 0.12 1.3e+02 6 22 .. 840 856 .. 839 861 .. 0.93 5 ? -0.9 0.0 4.7 5e+03 7 22 .. 881 896 .. 874 899 .. 0.62 6 ? 2.9 0.0 0.29 3.1e+02 6 22 .. 920 936 .. 919 938 .. 0.93 7 ? 2.5 0.0 0.38 4.1e+02 5 22 .. 959 976 .. 956 983 .. 0.86 8 ? 1.6 0.0 0.73 7.8e+02 10 28 .. 1004 1022 .. 1000 1024 .. 0.89 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 1.2 TPR_6 7 alsylelgdkdeAkaalqrlikk 29 +++y+ lg+ + + +++ i+ FUN_002346-T1 714 GRAYESLGNDYQSLGDFRKAIEY 736 67777777777777777777776 PP == domain 2 score: 2.4 bits; conditional E-value: 0.41 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ +A+++ FUN_002346-T1 760 LGNAYQSLGDFRKAIEY 776 799***********986 PP == domain 3 score: -0.7 bits; conditional E-value: 4 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+ + +++ FUN_002346-T1 800 LGSAYQSLGDFRKSIEY 816 799********999876 PP == domain 4 score: 4.1 bits; conditional E-value: 0.12 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y++lgd+ +A+++ FUN_002346-T1 840 LGSAYQALGDFRKAIEY 856 799***********986 PP == domain 5 score: -0.9 bits; conditional E-value: 4.7 TPR_6 7 alsylelgdkdeAkaa 22 + y+ lgd+ +A+++ FUN_002346-T1 881 GNDYQSLGDFRKAIEY 896 4445566777777664 PP == domain 6 score: 2.9 bits; conditional E-value: 0.29 TPR_6 6 lalsylelgdkdeAkaa 22 l+ +y+ lgd+++A+++ FUN_002346-T1 920 LGNAYQSLGDFKKAIEY 936 799***********986 PP == domain 7 score: 2.5 bits; conditional E-value: 0.38 TPR_6 5 klalsylelgdkdeAkaa 22 +l+ +y+ lg++ +A+++ FUN_002346-T1 959 NLGNAYQSLGEFRKAIEY 976 589************998 PP == domain 8 score: 1.6 bits; conditional E-value: 0.73 TPR_6 10 ylelgdkdeAkaalqrlik 28 y+ lg++++A++ +++ +k FUN_002346-T1 1004 YFSLGQFKKACDKFASAVK 1022 7889**********99887 PP >> RPN7 26S proteasome subunit RPN7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.1 0.014 15 20 72 .. 698 750 .. 686 752 .. 0.81 2 ? 1.3 0.0 0.32 3.4e+02 38 72 .. 756 790 .. 754 792 .. 0.86 3 ? -1.2 0.0 1.8 1.9e+03 38 71 .. 796 829 .. 794 832 .. 0.84 4 ? 1.8 0.1 0.23 2.4e+02 37 71 .. 835 869 .. 810 872 .. 0.82 5 ? 0.1 0.0 0.77 8.2e+02 38 65 .. 876 903 .. 874 912 .. 0.84 6 ? 4.3 0.2 0.037 39 38 73 .. 916 951 .. 914 1035 .. 0.79 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.014 RPN7 20 eaelkdakenlgkeeirraledlaehyakigdlenAlkayerarekttslghk 72 e++l+ ake + ra+e l++ y + gd+++A+++ e+ +e ++ gh FUN_002346-T1 698 EKHLEIAKEVSDRVGEGRAYESLGNDYQSLGDFRKAIEYHEKRLEIAIEVGHR 750 5666666666666666789***********************99999999986 PP == domain 2 score: 1.3 bits; conditional E-value: 0.32 RPN7 38 aledlaehyakigdlenAlkayerarekttslghk 72 a+ l++ y + gd+++A+++ e+ +e + gh FUN_002346-T1 756 AYGSLGNAYQSLGDFRKAIEYQEKHLEIAREVGHR 790 677899***************99999887777775 PP == domain 3 score: -1.2 bits; conditional E-value: 1.8 RPN7 38 aledlaehyakigdlenAlkayerarekttslgh 71 a+ l+ y + gd+++++++ e+ ++ + gh FUN_002346-T1 796 AYGSLGSAYQSLGDFRKSIEYHEKSLKIAREVGH 829 67789999**************998887766666 PP == domain 4 score: 1.8 bits; conditional E-value: 0.23 RPN7 37 raledlaehyakigdlenAlkayerarekttslgh 71 +a+ l+ y + gd+++A+++ e+ ++ + gh FUN_002346-T1 835 NAYGSLGSAYQALGDFRKAIEYHEKSLKIAREVGH 869 6788999*****************99887776666 PP == domain 5 score: 0.1 bits; conditional E-value: 0.77 RPN7 38 aledlaehyakigdlenAlkayerarek 65 a+ l++ y + gd+++A+++ e+ +e FUN_002346-T1 876 AYGSLGNDYQSLGDFRKAIEYHEKHLEI 903 67789999**************998875 PP == domain 6 score: 4.3 bits; conditional E-value: 0.037 RPN7 38 aledlaehyakigdlenAlkayerarekttslghki 73 a+ l++ y + gd+++A+++ e+ +e ++ gh + FUN_002346-T1 916 AYGSLGNAYQSLGDFKKAIEYHEKRLEIAIEVGHRV 951 567789999999999999999999999999998876 PP >> TPR_15 Tetratricopeptide repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.5 5.3e+02 223 246 .. 682 705 .. 668 708 .. 0.82 2 ? -3.3 0.0 6.3 6.7e+03 220 242 .. 719 741 .. 716 744 .. 0.79 3 ? 1.3 0.0 0.25 2.6e+02 219 246 .. 758 785 .. 753 787 .. 0.88 4 ? 0.5 0.0 0.44 4.7e+02 219 246 .. 798 825 .. 794 827 .. 0.89 5 ? 5.0 0.0 0.018 19 219 246 .. 838 865 .. 833 867 .. 0.89 6 ? -3.1 0.0 5.4 5.7e+03 221 243 .. 880 902 .. 877 905 .. 0.81 7 ? 0.6 0.0 0.39 4.2e+02 218 243 .. 917 942 .. 911 945 .. 0.88 8 ? -2.3 0.0 3.2 3.4e+03 220 240 .. 959 979 .. 956 984 .. 0.84 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.5 TPR_15 223 aAllllgqnrkALpyfrkkaaqnk 246 ++ +lg+ +kA +y +k+++ +k FUN_002346-T1 682 PGMTTLGDIQKAIEYHEKHLEIAK 705 3599**************998766 PP == domain 2 score: -3.3 bits; conditional E-value: 6.3 TPR_15 220 ayAaAllllgqnrkALpyfrkka 242 ++ + lg+ rkA +y +k++ FUN_002346-T1 719 SLGNDYQSLGDFRKAIEYHEKRL 741 56777889999999999999876 PP == domain 3 score: 1.3 bits; conditional E-value: 0.25 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + ++ A+ lg+ rkA +y +k+++ ++ FUN_002346-T1 758 GSLGNAYQSLGDFRKAIEYQEKHLEIAR 785 67899****************9988765 PP == domain 4 score: 0.5 bits; conditional E-value: 0.44 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + +++A+ lg+ rk +y +k ++ ++ FUN_002346-T1 798 GSLGSAYQSLGDFRKSIEYHEKSLKIAR 825 679*******************988765 PP == domain 5 score: 5.0 bits; conditional E-value: 0.018 TPR_15 219 eayAaAllllgqnrkALpyfrkkaaqnk 246 + +++A+ +lg+ rkA +y +k ++ ++ FUN_002346-T1 838 GSLGSAYQALGDFRKAIEYHEKSLKIAR 865 679*******************988765 PP == domain 6 score: -3.1 bits; conditional E-value: 5.4 TPR_15 221 yAaAllllgqnrkALpyfrkkaa 243 ++ + lg+ rkA +y +k+++ FUN_002346-T1 880 LGNDYQSLGDFRKAIEYHEKHLE 902 666788999********999875 PP == domain 7 score: 0.6 bits; conditional E-value: 0.39 TPR_15 218 weayAaAllllgqnrkALpyfrkkaa 243 ++ ++ A+ lg+ +kA +y +k+++ FUN_002346-T1 917 YGSLGNAYQSLGDFKKAIEYHEKRLE 942 567999***************99865 PP == domain 8 score: -2.3 bits; conditional E-value: 3.2 TPR_15 220 ayAaAllllgqnrkALpyfrk 240 ++ A+ lg+ rkA +y + FUN_002346-T1 959 NLGNAYQSLGEFRKAIEYHEN 979 6899*************9876 PP >> PPR PPR repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 6 6.4e+03 12 24 .. 726 738 .. 717 739 .. 0.82 2 ? 2.2 0.0 0.35 3.7e+02 3 22 .. 757 776 .. 756 779 .. 0.90 3 ? 1.0 0.0 0.88 9.4e+02 3 25 .. 797 819 .. 796 822 .. 0.90 4 ? 3.2 0.0 0.17 1.8e+02 3 25 .. 837 859 .. 836 862 .. 0.90 5 ? -0.6 0.0 2.7 2.8e+03 3 24 .. 877 898 .. 876 899 .. 0.79 6 ? 4.9 0.0 0.047 50 2 24 .. 916 938 .. 915 939 .. 0.91 7 ? 1.0 0.0 0.82 8.7e+02 3 24 .. 957 978 .. 956 982 .. 0.86 8 ? -0.9 0.0 3.3 3.5e+03 8 21 .. 1002 1015 .. 1000 1019 .. 0.88 9 ? -0.1 0.0 2 2.1e+03 2 20 .. 1048 1066 .. 1047 1067 .. 0.89 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 6 PPR 12 knGkleeAlelfk 24 + G++++A+e+++ FUN_002346-T1 726 SLGDFRKAIEYHE 738 68********987 PP == domain 2 score: 2.2 bits; conditional E-value: 0.35 PPR 3 ynslIsgycknGkleeAlel 22 y sl ++y + G++++A+e+ FUN_002346-T1 757 YGSLGNAYQSLGDFRKAIEY 776 99999************986 PP == domain 3 score: 1.0 bits; conditional E-value: 0.88 PPR 3 ynslIsgycknGkleeAlelfke 25 y sl s+y + G++++ +e++++ FUN_002346-T1 797 YGSLGSAYQSLGDFRKSIEYHEK 819 99999*************99876 PP == domain 4 score: 3.2 bits; conditional E-value: 0.17 PPR 3 ynslIsgycknGkleeAlelfke 25 y sl s+y G++++A+e++++ FUN_002346-T1 837 YGSLGSAYQALGDFRKAIEYHEK 859 89999**************9886 PP == domain 5 score: -0.6 bits; conditional E-value: 2.7 PPR 3 ynslIsgycknGkleeAlelfk 24 y sl + y + G++++A+e+++ FUN_002346-T1 877 YGSLGNDYQSLGDFRKAIEYHE 898 66666667789********987 PP == domain 6 score: 4.9 bits; conditional E-value: 0.047 PPR 2 tynslIsgycknGkleeAlelfk 24 +y sl ++y + G++++A+e+++ FUN_002346-T1 916 AYGSLGNAYQSLGDFKKAIEYHE 938 799*****************987 PP == domain 7 score: 1.0 bits; conditional E-value: 0.82 PPR 3 ynslIsgycknGkleeAlelfk 24 y l ++y + G++++A+e+++ FUN_002346-T1 957 YGNLGNAYQSLGEFRKAIEYHE 978 777889************9876 PP == domain 8 score: -0.9 bits; conditional E-value: 3.3 PPR 8 sgycknGkleeAle 21 +gy + G++++A + FUN_002346-T1 1002 HGYFSLGQFKKACD 1015 69**********86 PP == domain 9 score: -0.1 bits; conditional E-value: 2 PPR 2 tynslIsgycknGkleeAl 20 +y ++ +++ + Gk++eAl FUN_002346-T1 1048 SYCAMWRSLLRIGKIDEAL 1066 788888999*********7 PP >> SHNi-TPR SHNi-TPR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 9.2 9.8e+03 19 29 .. 725 735 .. 725 739 .. 0.81 2 ? 4.2 0.0 0.042 44 19 36 .. 765 782 .. 764 783 .. 0.90 3 ? -2.9 0.0 6.5 7e+03 19 29 .. 805 815 .. 805 821 .. 0.77 4 ? 0.8 0.0 0.47 5.1e+02 19 31 .. 845 857 .. 844 862 .. 0.83 5 ? 0.1 0.0 0.75 7.9e+02 19 36 .. 885 902 .. 884 903 .. 0.87 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 9.2 SHNi-TPR 19 qAvkDlrkaLe 29 q + D+rka+e FUN_002346-T1 725 QSLGDFRKAIE 735 6677*****97 PP == domain 2 score: 4.2 bits; conditional E-value: 0.042 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D+rka+e +e++l+ FUN_002346-T1 765 QSLGDFRKAIEYQEKHLE 782 6778************96 PP == domain 3 score: -2.9 bits; conditional E-value: 6.5 SHNi-TPR 19 qAvkDlrkaLe 29 q + D+rk++e FUN_002346-T1 805 QSLGDFRKSIE 815 6677*****98 PP == domain 4 score: 0.8 bits; conditional E-value: 0.47 SHNi-TPR 19 qAvkDlrkaLeLr 31 qA+ D+rka+e FUN_002346-T1 845 QALGDFRKAIEYH 857 9********9855 PP == domain 5 score: 0.1 bits; conditional E-value: 0.75 SHNi-TPR 19 qAvkDlrkaLeLreellp 36 q + D+rka+e e++l+ FUN_002346-T1 885 QSLGDFRKAIEYHEKHLE 902 6778*******9999986 PP >> GGDEF_2 GGDEF-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 2.6 2.8e+03 75 107 .. 702 734 .. 683 738 .. 0.81 2 ? 0.8 0.0 0.73 7.8e+02 75 107 .. 742 774 .. 728 778 .. 0.78 3 ? 4.7 0.1 0.047 50 75 107 .. 782 814 .. 774 821 .. 0.89 4 ? 1.0 0.0 0.67 7.1e+02 75 107 .. 822 854 .. 814 856 .. 0.86 5 ? -0.4 0.0 1.8 1.9e+03 75 107 .. 862 894 .. 853 898 .. 0.87 6 ? 0.4 0.0 1 1.1e+03 75 107 .. 902 934 .. 888 936 .. 0.81 7 ? -1.0 0.0 2.7 2.9e+03 90 114 .. 950 974 .. 934 976 .. 0.63 8 ? 0.9 0.0 0.68 7.2e+02 51 91 .. 1396 1436 .. 1390 1448 .. 0.72 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 2.6 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++++r+g+ +++ +G+ +++l ++r++ FUN_002346-T1 702 EIAKEVSDRVGEGRAYESLGNDYQSLGDFRKAI 734 889999999999999999999999999999875 PP == domain 2 score: 0.8 bits; conditional E-value: 0.73 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++ +r+g+ +++ +G+++++l ++r++ FUN_002346-T1 742 EIAIEVGHRVGEGNAYGSLGNAYQSLGDFRKAI 774 566667777777888889999999999999875 PP == domain 3 score: 4.7 bits; conditional E-value: 0.047 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e+++++ +r+g+ +++ +G+++++l ++r+S FUN_002346-T1 782 EIAREVGHRVGEGNAYGSLGSAYQSLGDFRKSI 814 899999999999*******************96 PP == domain 4 score: 1.0 bits; conditional E-value: 0.67 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 ++++++ +r+g+ +++ +G++++ l ++r++ FUN_002346-T1 822 KIAREVGHRVGEGNAYGSLGSAYQALGDFRKAI 854 7889999999999999*************9985 PP == domain 5 score: -0.4 bits; conditional E-value: 1.8 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 ++++++ +r+g+ +++ +G+ +++l ++r++ FUN_002346-T1 862 KIAREVGHRVGEGNAYGSLGNDYQSLGDFRKAI 894 7889999999999*****************985 PP == domain 6 score: 0.4 bits; conditional E-value: 1 GGDEF_2 75 ellerlrrrlggitvriGvGrpveglaglrrSy 107 e++ ++++r+g+ +++ +G+++++l ++ ++ FUN_002346-T1 902 EIAIEVSDRVGEGSAYGSLGNAYQSLGDFKKAI 934 677788899999999999999999999999875 PP == domain 7 score: -1.0 bits; conditional E-value: 2.7 GGDEF_2 90 riGvGrpveglaglrrSyreArrAl 114 r+G G+++ +l ++++S e r+A+ FUN_002346-T1 950 RVGEGNAYGNLGNAYQSLGEFRKAI 974 5666666666666666666655555 PP == domain 8 score: 0.9 bits; conditional E-value: 0.68 GGDEF_2 51 dalvavrgdrlvlllpvddeadaeellerlrrrlgg.itvri 91 +l+a ++ lv+l++ ddea+ e+++r+ ++l++ t+++ FUN_002346-T1 1396 AFLAAGARSVLVALWAIDDEAT-MEFMKRFYQQLKEgKTASA 1436 56777788899********865.6788888888877444444 PP >> ARM_TT21_4th Tetratricopeptide repeat protein 21 forth ARM domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.1 4.5 4.7e+03 38 73 .. 463 496 .. 451 512 .. 0.71 2 ? -0.9 0.0 2.3 2.5e+03 6 27 .. 721 742 .. 718 746 .. 0.78 3 ? 0.8 0.0 0.68 7.2e+02 5 28 .. 760 783 .. 758 789 .. 0.87 4 ? 0.4 0.0 0.9 9.6e+02 5 29 .. 800 824 .. 798 830 .. 0.89 5 ? 3.7 0.0 0.09 96 5 29 .. 840 864 .. 838 871 .. 0.88 6 ? -0.8 0.0 2.2 2.4e+03 6 27 .. 881 902 .. 879 907 .. 0.77 7 ? 2.9 0.0 0.16 1.7e+02 5 27 .. 920 942 .. 918 947 .. 0.88 8 ? 3.9 0.1 0.078 83 5 29 .. 960 984 .. 958 1023 .. 0.78 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 4.5 ARM_TT21_4th 38 LAeLllkLkqydkaekvlkqaleeekskdleslmee 73 eL +kL +a+++lk++ +ee +k+l++l ++ FUN_002346-T1 463 YGELVIKL--LIDANNTLKEKEKEEIKKTLTKLVQT 496 56666666..45788888888888888888877765 PP == domain 2 score: -0.9 bits; conditional E-value: 2.3 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G+ + +++kAi+Y e+ l+ FUN_002346-T1 721 GNDYQSLGDFRKAIEYHEKRLE 742 6666777789******998765 PP == domain 3 score: 0.8 bits; conditional E-value: 0.68 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalks 28 +G+a+ +++kAi+Y e+ l++ FUN_002346-T1 760 LGNAYQSLGDFRKAIEYQEKHLEI 783 79999999*********9988765 PP == domain 4 score: 0.4 bits; conditional E-value: 0.9 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G a+ +++k i+Y e+ lk+ FUN_002346-T1 800 LGSAYQSLGDFRKSIEYHEKSLKIA 824 799999999***********99976 PP == domain 5 score: 3.7 bits; conditional E-value: 0.09 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G a+ +++kAi+Y e+ lk+ FUN_002346-T1 840 LGSAYQALGDFRKAIEYHEKSLKIA 864 699999999************9976 PP == domain 6 score: -0.8 bits; conditional E-value: 2.2 ARM_TT21_4th 6 GqalvktHqYkkAinYYeaalk 27 G+ + +++kAi+Y e+ l+ FUN_002346-T1 881 GNDYQSLGDFRKAIEYHEKHLE 902 56666667899*****998776 PP == domain 7 score: 2.9 bits; conditional E-value: 0.16 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalk 27 +G+a+ ++kkAi+Y e+ l+ FUN_002346-T1 920 LGNAYQSLGDFKKAIEYHEKRLE 942 799***************98776 PP == domain 8 score: 3.9 bits; conditional E-value: 0.078 ARM_TT21_4th 5 iGqalvktHqYkkAinYYeaalkss 29 +G+a+ +++kAi+Y e+ lk+ FUN_002346-T1 960 LGNAYQSLGEFRKAIEYHENFLKIA 984 799****************999864 PP >> UFL1_C E3 UFM1-protein ligase 1 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.5 0.00073 0.78 61 108 .. 453 495 .. 449 502 .. 0.79 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00073 UFL1_C 61 peeqfklLseYqslvVkqlklqskkeeeeeeeeeeaeeieeeLeellp 108 +e ++ L +Y +lv+k l +++ +e+e+ eei+++L +l++ FUN_002346-T1 453 GSEGQQSLRKYGELVIKLLIDANNTLKEKEK-----EEIKKTLTKLVQ 495 567899**************99998888554.....567777777665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1479 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 907 (0.035506); expected 510.9 (0.02) Passed bias filter: 809 (0.0316696); expected 510.9 (0.02) Passed Vit filter: 86 (0.00336661); expected 25.5 (0.001) Passed Fwd filter: 30 (0.0011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 24 [number of targets reported over threshold] # CPU time: 0.58u 0.41s 00:00:00.99 Elapsed: 00:00:00.44 # Mc/sec: 13641.05 // Query: FUN_002347-T1 [L=174] Description: FUN_002347 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (174 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 244 (0.00955177); expected 510.9 (0.02) Passed bias filter: 229 (0.00896457); expected 510.9 (0.02) Passed Vit filter: 10 (0.000391466); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.25u 0.40s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1754.01 // Query: FUN_002348-T1 [L=158] Description: FUN_002348 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (158 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 673 (0.0263457); expected 510.9 (0.02) Passed bias filter: 445 (0.0174202); expected 510.9 (0.02) Passed Vit filter: 19 (0.000743785); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.34s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1595.92 // Query: FUN_002349-T1 [L=341] Description: FUN_002349 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00017 20.6 7.4 0.04 12.7 3.7 3.0 4 Vps62 Vacuolar protein sorting-associated protein 62 Domain annotation for each model (and alignments): >> Vps62 Vacuolar protein sorting-associated protein 62 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.0 0.0 4.2e-05 1.1 236 267 .. 25 56 .. 4 66 .. 0.85 2 ? -3.3 0.0 0.12 2.9e+03 336 357 .. 122 143 .. 120 145 .. 0.83 3 ! 12.7 3.7 1.6e-06 0.04 364 431 .. 169 252 .. 166 307 .. 0.68 4 ? -3.6 0.0 0.14 3.5e+03 514 531 .. 318 335 .. 317 336 .. 0.83 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 4.2e-05 Vps62 236 eqikalikaygptvyfhpdeeylpssvsWffk 267 ++i li++++p+v + ++e + pssv++f++ FUN_002349-T1 25 SKIGDLIDKWAPLVKLAKNEPWKPSSVDYFLS 56 57899*************************87 PP == domain 2 score: -3.3 bits; conditional E-value: 0.12 Vps62 336 ftDialWvfyPfnGpatlkvgl 357 f +ia +f+P+n ++ vgl FUN_002349-T1 122 FLEIAYRMFFPYNRGKRVCVGL 143 7789999******988888876 PP == domain 3 score: 12.7 bits; conditional E-value: 1.6e-06 Vps62 364 kiGehvgdWehvtlrisnfsg..eLlsvyfsqhs.......gGewv.......dasdlefieggnkavvysskhghasypkpgl 431 + G+hvgdWe v +r ++ +++s+y+s h gGe++ + + gg +a+vy + +h ++p +g FUN_002349-T1 169 TFGHHVGDWEKVYVRFQKVNSdyQIYSIYLSMHGsavtkqfGGEFLwqggqfkKGGRTLGMYGGTHAIVYCAAGSHGMWPDTGR 252 67*************97665522799******9623333333333311110002222122244577777877777887777775 PP == domain 4 score: -3.6 bits; conditional E-value: 0.14 Vps62 514 lvkklPvellgeeGPtGP 531 ++++l e + ++GPtGP FUN_002349-T1 318 VLEDLVGECMLNNGPTGP 335 567788899999*****9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (341 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 575 (0.0225093); expected 510.9 (0.02) Passed bias filter: 373 (0.0146017); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.42s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 3404.10 // Query: FUN_002350-T1 [L=480] Description: FUN_002350 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.6e-18 66.3 50.1 3.7e-13 49.8 7.2 3.7 3 IBR IBR domain, a half RING-finger domain 6.4e-13 48.8 20.3 6.4e-13 48.8 20.3 4.4 4 IBR_1 IBR domain 3.7e-12 46.5 0.0 9.1e-12 45.2 0.0 1.7 1 UBA_ARIH2_N E3 ubiquitin-protein ligase ARIH2, N-terminal U 1.5e-11 45.0 12.7 3.4e-11 43.9 9.2 2.6 2 Ariadne Ariadne domain 5.9e-07 30.0 16.2 5.9e-07 30.0 16.2 3.3 3 IBR_2 IBR domain 4.3e-05 23.7 0.4 9.6e-05 22.6 0.4 1.5 1 UBA_ARI1 E3 ubiquitin-protein ligase ARIH1, UBA-like dom 0.00033 20.9 8.6 0.00033 20.9 8.6 4.4 4 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) 0.002 18.5 8.9 0.002 18.5 8.9 3.4 3 zf-RING_UBOX RING-type zinc-finger ------ inclusion threshold ------ 0.027 15.2 11.7 0.027 15.2 11.7 4.0 3 zf-RING_2 Ring finger domain 2.1 9.2 4.4 2.9 8.7 0.1 2.9 3 NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 Domain annotation for each model (and alignments): >> IBR IBR domain, a half RING-finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.5 6.9 0.17 4.4e+02 13 55 .. 120 154 .. 112 161 .. 0.58 2 ! 49.8 7.2 1.4e-16 3.7e-13 1 65 [] 196 258 .. 196 258 .. 0.95 3 ! 26.5 20.0 2.7e-09 6.9e-06 15 60 .. 279 321 .. 267 328 .. 0.87 Alignments for each domain: == domain 1 score: 1.5 bits; conditional E-value: 0.17 IBR 13 es.dpnlkwCptpdCekiiekeegkkkcnkvtCskCgtefCfkC 55 ++ + + Cp C + + k++ ++ + Cg+ fC +C FUN_002350-T1 120 SQtTTRSILCP--VCFQRCAKSNT---SSA---P-CGHTFCNDC 154 44355567787..77755544444...333...3.777777777 PP == domain 2 score: 49.8 bits; conditional E-value: 1.4e-16 IBR 1 ekyeklllkkylesdpnlkwCptpdCekiiekeegkkkcnkvtCskCgtefCfkCkeewHegltC 65 eky ++l+++ ++ +p ++wCp +dC+ ++++ e+ k ++v Cs+C + fCf C+e++H++++C FUN_002350-T1 196 EKYRQFLFNDEVKGHPLIRWCPGNDCGCLVKVVES--KAKRVWCSNCYSVFCFMCGEKYHAPTDC 258 79****************************99999..566778*********************9 PP == domain 3 score: 26.5 bits; conditional E-value: 2.7e-09 IBR 15 dpnlkwCptpdCekiiekeegkkkcnkvtCskCgtefCfkCkeew..H 60 ++n+k Cp +C++ iek++g cn+++C kC+++fC+ C +w H FUN_002350-T1 279 TANTKDCP--NCGSCIEKNGG---CNHMQCIKCKHDFCWMCCGDWrtH 321 5799****..***********...*********************444 PP >> IBR_1 IBR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 8.2 0.59 1.5e+03 6 37 .. 129 156 .. 125 163 .. 0.50 2 ? 0.4 0.0 0.35 8.9e+02 2 11 .. 169 178 .. 168 183 .. 0.81 3 ? 4.9 11.7 0.014 35 9 44 .. 221 257 .. 212 268 .. 0.79 4 ! 48.8 20.3 2.5e-16 6.4e-13 1 40 [. 280 319 .. 280 329 .. 0.95 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 0.59 IBR_1 6 CpkCkfryelar.gcmhftCkqCkheFCsgCkr 37 Cp C r +++ C h+FC C FUN_002350-T1 129 CPVCFQRCAKSNtS-----SAPCGHTFCNDCWM 156 55555555544311.....11266666666643 PP == domain 2 score: 0.4 bits; conditional E-value: 0.35 IBR_1 2 ngieCpkCkf 11 +gieC +C FUN_002350-T1 169 SGIECMNCDL 178 799*****75 PP == domain 3 score: 4.9 bits; conditional E-value: 0.014 IBR_1 9 Ckfryelar.gcmhftCkqCkheFCsgCkrpfeagkk 44 C ++ ++ C+ C FC +C ++++a + FUN_002350-T1 221 CGCLVKVVEsKAKRVWCSNCYSVFCFMCGEKYHAPTD 257 6666666555788999*****************7666 PP == domain 4 score: 48.8 bits; conditional E-value: 2.5e-16 IBR_1 1 engieCpkCkfryelargcmhftCkqCkheFCsgCkrpfe 40 +n+++Cp+C + +e+++gc+h++C +Ckh+FC++C+++++ FUN_002350-T1 280 ANTKDCPNCGSCIEKNGGCNHMQCIKCKHDFCWMCCGDWR 319 69*************************************9 PP >> UBA_ARIH2_N E3 ubiquitin-protein ligase ARIH2, N-terminal UBA domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.2 0.0 3.6e-15 9.1e-12 3 54 .. 59 110 .. 57 111 .. 0.94 Alignments for each domain: == domain 1 score: 45.2 bits; conditional E-value: 3.6e-15 UBA_ARIH2_N 3 EserlLnEeveslaaaLkVspsvAKllLvhfhWqvseIldrYksnssqlLve 54 E+ ++++ v+++++ +kV++svA+llL++++W+++ Il+r++ + + +Lve FUN_002350-T1 59 EAGQIFDSMVAKVSQEIKVTKSVARLLLIQHEWNTEKILERHRVDPVGMLVE 110 788899999************************************9999987 PP >> Ariadne Ariadne domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 2 5.1e+03 206 243 .. 26 63 .. 3 66 .. 0.58 2 ! 43.9 9.2 1.3e-14 3.4e-11 2 115 .. 352 452 .. 351 471 .. 0.87 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 2 Ariadne 206 ekpsasgsseesgcssrkrarkeasgdklfdlnlpaev 243 + ++ s+++g+ss k + e+++ ++d n ++ FUN_002350-T1 26 VDDYYTNVSDDEGMSSDKEEDPESFEFVIIDTNEAGQI 63 23335667788888888888888888888887766555 PP == domain 2 score: 43.9 bits; conditional E-value: 1.3e-14 Ariadne 2 rymhyhnrykahtdsfklesklketikekvsileerd.sklkdfsWvtnGlyrlfrsrrvlsysypfafymfGdelfkdemtkeereikqnlfedq 96 +y+ y++r++ h+ds+k e++ k +i++k+ +++ + d+ ++ + l r+r l y+yp+a++m d +++lfe q FUN_002350-T1 352 KYLFYFERWQNHADSLKREEETKRKINQKIQEKVNNNiGTWIDWQYLLDAALLLARCRYTLMYTYPYAYFMEDD--------------RKKLFEYQ 433 8*****************************987666615789****************************9433..............579***** PP Ariadne 97 qqqleanveklskfleepf 115 q qle ++e+ls le++ FUN_002350-T1 434 QAQLELEIENLSWKLERDE 452 **************99874 PP >> IBR_2 IBR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -6.1 5.5 10 2.6e+04 29 39 .. 144 154 .. 128 161 .. 0.57 2 ? -4.6 6.7 10 2.6e+04 17 40 .. 219 241 .. 206 259 .. 0.53 3 ! 30.0 16.2 2.3e-10 5.9e-07 2 44 .. 279 319 .. 278 322 .. 0.92 Alignments for each domain: == domain 1 score: -6.1 bits; conditional E-value: 10 IBR_2 29 agCdfhWCWvC 39 a C++ +C C FUN_002350-T1 144 APCGHTFCNDC 154 44555555444 PP == domain 2 score: -4.6 bits; conditional E-value: 10 IBR_2 17 rdGGCmhmvCtragCdfhWCWvCq 40 d GC+ v + + WC C FUN_002350-T1 219 NDCGCLVKVV-ESKAKRVWCSNCY 241 5666665553.3333444444332 PP == domain 3 score: 30.0 bits; conditional E-value: 2.3e-10 IBR_2 2 kvltkPCPkCrtpterdGGCmhmvCtragCdfhWCWvCqmeWt 44 tk CP+C e++GGC hm C++ C++++CW+C ++W FUN_002350-T1 279 TANTKDCPNCGSCIEKNGGCNHMQCIK--CKHDFCWMCCGDWR 319 568**********************96..9************6 PP >> UBA_ARI1 E3 ubiquitin-protein ligase ARIH1, UBA-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.4 3.7e-08 9.6e-05 5 38 .. 66 99 .. 63 100 .. 0.94 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 3.7e-08 UBA_ARI1 5 eeIdeVssiLglppetariLLrhfkWnkEkLiEr 38 +++++Vs+ +++ +++ar+LL ++ Wn Ek +Er FUN_002350-T1 66 SMVAKVSQEIKVTKSVARLLLIQHEWNTEKILER 99 678999999***********************98 PP >> zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 8.6 1.3e-07 0.00033 2 28 .. 129 156 .. 128 162 .. 0.84 2 ? 0.4 3.4 0.31 8e+02 16 30 .. 238 252 .. 229 258 .. 0.80 3 ? -0.9 0.6 0.8 2.1e+03 34 40 .] 282 288 .. 274 288 .. 0.72 4 ? 1.0 12.1 0.21 5.3e+02 13 30 .. 301 318 .. 291 328 .. 0.83 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1.3e-07 zf-C3HC4_2 2 CpiCldmlkdplvvt.pCgHvfCqkCil 28 Cp+C+ + + ++ pCgH+fC++C++ FUN_002350-T1 129 CPVCFQRCAKSNTSSaPCGHTFCNDCWM 156 ******9987655445***********8 PP == domain 2 score: 0.4 bits; conditional E-value: 0.31 zf-C3HC4_2 16 tpCgHvfCqkCilra 30 +C vfC +C ++ FUN_002350-T1 238 SNCYSVFCFMCGEKY 252 58999******9886 PP == domain 3 score: -0.9 bits; conditional E-value: 0.8 zf-C3HC4_2 34 sneCPlC 40 + CP C FUN_002350-T1 282 TKDCPNC 288 459***9 PP == domain 4 score: 1.0 bits; conditional E-value: 0.21 zf-C3HC4_2 13 lvvtpCgHvfCqkCilra 30 + ++C+H fC +C + FUN_002350-T1 301 MQCIKCKHDFCWMCCGDW 318 5789**********8776 PP >> zf-RING_UBOX RING-type zinc-finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 8.9 8e-07 0.002 1 25 [. 129 155 .. 129 173 .. 0.75 2 ? -5.0 3.5 10 2.6e+04 1 11 [. 245 255 .. 237 259 .. 0.65 3 ? -3.3 12.9 5.2 1.3e+04 15 31 .. 305 323 .. 285 329 .. 0.67 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 8e-07 zf-RING_UBOX 1 CpICleeft..dPlvl.pCGHtfCreCl 25 Cp+C++ + + pCGHtfC +C FUN_002350-T1 129 CPVCFQRCAksN-TSSaPCGHTFCNDCW 155 ******999653.35349*********5 PP == domain 2 score: -5.0 bits; conditional E-value: 10 zf-RING_UBOX 1 CpICleeftdP 11 C C e ++ P FUN_002350-T1 245 CFMCGEKYHAP 255 45566777666 PP == domain 3 score: -3.3 bits; conditional E-value: 5.2 zf-RING_UBOX 15 pCGHtfCreCl..welskk 31 +C H fC+ C+ w+++++ FUN_002350-T1 305 KCKHDFCWMCCgdWRTHGS 323 6**********77654443 PP >> zf-RING_2 Ring finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 11.7 1.1e-05 0.027 2 43 .. 128 176 .. 127 177 .. 0.75 2 ? -5.1 11.9 10 2.6e+04 17 43 .. 245 288 .. 219 289 .. 0.50 3 ? 0.3 18.9 0.47 1.2e+03 2 39 .. 287 324 .. 283 329 .. 0.82 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.1e-05 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst........CPlC 43 Cp+C++++ + +++ pCgH+f+ +C + ++ ++ + C +C FUN_002350-T1 128 LCPVCFQRCAK-SNTSSAPCGHTFCNDCWMLYCVNQLKiglasgieCMNC 176 5*****99955.6666678*********8777766665666666667766 PP == domain 2 score: -5.1 bits; conditional E-value: 10 zf-RING_2 17 ivlpCgHvfh..keC..ldkwlrtsst..............CPlC 43 + + Cg +h +C ++kwl++ ++ CP+C FUN_002350-T1 245 CFM-CGEKYHapTDCytIKKWLTKCEDdsetanyitantkdCPNC 288 223.55444422234223555555544444444455555556666 PP == domain 3 score: 0.3 bits; conditional E-value: 0.47 zf-RING_2 2 eCpiCleeleeeekvivlpCgHvfhkeCldkwlrtsst 39 +C C e+ +++++ +C+H f++ C +w ++ s+ FUN_002350-T1 287 NCGSCIEKNGGCNHMQCIKCKHDFCWMCCGDWRTHGSE 324 6888888888888888889*999*********888766 PP >> NRBF2_MIT MIT domain of nuclear receptor-binding factor 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 0.1 0.0011 2.9 40 82 .. 59 101 .. 55 102 .. 0.91 2 ? -1.3 0.3 1.5 3.7e+03 57 80 .. 345 372 .. 337 384 .. 0.68 3 ? 0.2 0.0 0.51 1.3e+03 40 58 .. 425 443 .. 404 451 .. 0.83 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0011 NRBF2_MIT 40 eamkltkseqahlslelqreshikqllliqerwkrakreersk 82 ea ++ s a++s e++ + +llliq w+ k er++ FUN_002350-T1 59 EAGQIFDSMVAKVSQEIKVTKSVARLLLIQHEWNTEKILERHR 101 6778889999*************************99999986 PP == domain 2 score: -1.3 bits; conditional E-value: 1.5 NRBF2_MIT 57 qreshikqllliqerwkra....kreer 80 q +k+ l+ erw+ kree FUN_002350-T1 345 QAREALKKYLFYFERWQNHadslKREEE 372 6566678888888898752122256554 PP == domain 3 score: 0.2 bits; conditional E-value: 0.51 NRBF2_MIT 40 eamkltkseqahlslelqr 58 + kl + +qa+l le++ FUN_002350-T1 425 DRKKLFEYQQAQLELEIEN 443 456899999******9875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (480 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1993 (0.0780192); expected 510.9 (0.02) Passed bias filter: 615 (0.0240752); expected 510.9 (0.02) Passed Vit filter: 70 (0.00274026); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.36u 0.41s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4568.35 // Query: FUN_002351-T1 [L=574] Description: FUN_002351 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-11 43.7 0.0 6.8e-11 42.8 0.0 1.5 1 DRMBL DNA repair metallo-beta-lactamase ------ inclusion threshold ------ 0.083 13.8 0.3 0.38 11.6 0.1 2.3 3 DUF5805 Family of unknown function (DUF5805) Domain annotation for each model (and alignments): >> DRMBL DNA repair metallo-beta-lactamase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.8 0.0 5.3e-15 6.8e-11 4 106 .. 182 286 .. 179 288 .. 0.89 Alignments for each domain: == domain 1 score: 42.8 bits; conditional E-value: 5.3e-15 DRMBL 4 ssllttdpseaqvhvvplkkls...keklekylkalkekfdevlairPtg.wtkkekkkevlekikessrgkitiygvpYSeHSSfeELkefvkfl 95 +ttd +++++h+++ + + +++l+++ +++ + +vl i+P + w + + + + +++ ++ +++v S+H S+eE+++ v +l FUN_002351-T1 182 LPYFTTDGRATKIHACKWQANRhdaDSDLPCGQSTFPARKMKVLRIKPATmWVALSTEGMPAD--FKRYDKEQRVWRVVHSMHASMEEVQDLVGYL 275 6789************999766566899**********************9**9998777777..5556899************************ PP DRMBL 96 kpkkiiptVnv 106 kp + +p+V++ FUN_002351-T1 276 KPYHAYPNVPP 286 *********97 PP >> DUF5805 Family of unknown function (DUF5805) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 1.6 2e+04 19 42 .. 140 162 .. 138 166 .. 0.76 2 ? -3.8 0.1 1.9 2.5e+04 15 35 .. 251 270 .. 249 272 .. 0.73 3 ? 11.6 0.1 3e-05 0.38 21 47 .. 381 407 .. 376 422 .. 0.90 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 1.6 DUF5805 19 leaLesegvlswDeLvealtdDiE 42 +++L +g++ ++ L+ +++ ++ FUN_002351-T1 140 VSLL-CKGMYGFEYLLKEVAMHFK 162 5556.7899999999999987776 PP == domain 2 score: -3.8 bits; conditional E-value: 1.9 DUF5805 15 edrvleaLesegvlswDeLve 35 e+rv +++ + ++s +e+ + FUN_002351-T1 251 EQRVWRVV-HSMHASMEEVQD 270 68888888.777778887766 PP == domain 3 score: 11.6 bits; conditional E-value: 3e-05 DUF5805 21 aLesegvlswDeLvealtdDiEdrLde 47 +Le++ v sw +L e+lt D+E++L FUN_002351-T1 381 ILEERKVDSWQQLTEELTLDFEKELIS 407 799999*****************9965 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (574 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 598 (0.0234097); expected 510.9 (0.02) Passed bias filter: 527 (0.0206303); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 5582.41 // Query: FUN_002351-T2 [L=636] Description: FUN_002351 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.5e-11 43.7 0.0 8e-11 42.6 0.0 1.7 1 DRMBL DNA repair metallo-beta-lactamase 3.1e-06 27.6 0.3 7.3e-06 26.4 0.3 1.6 1 Anti-Pycsar_Apyc1 Anti-Pycsar protein Apyc1 0.00049 20.2 0.0 0.0019 18.3 0.0 1.9 2 Lactamase_B_2 Beta-lactamase superfamily domain ------ inclusion threshold ------ 0.082 13.8 0.0 0.44 11.4 0.2 2.2 2 DUF5805 Family of unknown function (DUF5805) 0.49 10.8 2.2 15 6.0 0.1 2.6 2 Lactamase_B Metallo-beta-lactamase superfamily Domain annotation for each model (and alignments): >> DRMBL DNA repair metallo-beta-lactamase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.6 0.0 1.6e-14 8e-11 4 106 .. 244 348 .. 241 350 .. 0.89 Alignments for each domain: == domain 1 score: 42.6 bits; conditional E-value: 1.6e-14 DRMBL 4 ssllttdpseaqvhvvplkkls...keklekylkalkekfdevlairPtg.wtkkekkkevlekikessrgkitiygvpYSeHSSfeELkefvkfl 95 +ttd +++++h+++ + + +++l+++ +++ + +vl i+P + w + + + + +++ ++ +++v S+H S+eE+++ v +l FUN_002351-T2 244 LPYFTTDGRATKIHACKWQANRhdaDSDLPCGQSTFPARKMKVLRIKPATmWVALSTEGMPAD--FKRYDKEQRVWRVVHSMHASMEEVQDLVGYL 337 6789************999766566899**********************9**9998777777..5556899************************ PP DRMBL 96 kpkkiiptVnv 106 kp + +p+V++ FUN_002351-T2 338 KPYHAYPNVPP 348 *********97 PP >> Anti-Pycsar_Apyc1 Anti-Pycsar protein Apyc1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.3 1.4e-09 7.3e-06 54 170 .. 28 142 .. 14 165 .. 0.81 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 1.4e-09 Anti-Pycsar_Apyc1 54 avlitHlHaDHvgGLeelalqrkfkekkkpkLyiseelveeLWeksLkggleseeeeeasledyfdvkplkeeesfeieglelelvrtkHip 145 a++++H+H+DH+ GL+ a++++ + +k + Ly+se+ ++ L s l+s+ ++ le+ ++pl ++++ e +++ ++l++ H+ FUN_002351-T2 28 AFFLSHCHKDHMSGLDSKAFHTRLMGSKSVFLYCSETTENLLLCDSSYSHLKSHV-HSIPLEQQT-MIPLFDDNTDEESSICVTLLPAGHCV 117 679************************************9997766666666555.345566654.44555555567789***********9 PP Anti-Pycsar_Apyc1 146 skkpsyglll...nekifysaDtrfdpe 170 + s+ +l+ +++y++D r++ FUN_002351-T2 118 G---SVMFLFegqHGNVLYTGDFRLSVG 142 5...557777888899******998765 PP >> Lactamase_B_2 Beta-lactamase superfamily domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 3.7e-07 0.0019 34 144 .. 29 138 .. 20 154 .. 0.84 2 ? -3.3 0.0 1.5 7.8e+03 65 103 .. 235 272 .. 225 288 .. 0.75 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 3.7e-07 Lactamase_B_2 34 vllthdHiDHlaglltlre....lrpkr.lplyapagvlehlerrfvyafleeepgvrvveldwgesfev........gdggltvtatparhksgr 116 +l+h H DH+ gl++ + + +++ + ly+++ + l y l+++ v+ + ++++ + +++++ vt +pa h g FUN_002351-T2 29 FFLSHCHKDHMSGLDSKAFhtrlM-GSKsVFLYCSETTENLLLCDSSYSHLKSH----VHSIPLEQQTMIplfddntdEESSICVTLLPAGHCVGS 119 589*********999877766743.33348899*********999999999999....777777777777778888886778999*******9998 PP Lactamase_B_2 117 rldrnegdtlGlviegggkrvyyagDtg 144 + +++eg+ +v y+gD FUN_002351-T2 120 ---------VMFLFEGQHGNVLYTGDFR 138 .........99***************86 PP == domain 2 score: -3.3 bits; conditional E-value: 1.5 Lactamase_B_2 65 gvlehlerrfvyafleeepgvrvveldwgesfevgdggl 103 +++++l + ++y+ + +++++ +w+ + + +d++l FUN_002351-T2 235 RMYRYLPDMLPYFTTDGR-ATKIHACKWQANRHDADSDL 272 677888888888888888.88888888877766666554 PP >> DUF5805 Family of unknown function (DUF5805) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.9 0.0 5 2.6e+04 19 42 .. 202 224 .. 200 227 .. 0.76 2 ? 11.4 0.2 8.7e-05 0.44 21 47 .. 443 469 .. 438 482 .. 0.90 Alignments for each domain: == domain 1 score: -3.9 bits; conditional E-value: 5 DUF5805 19 leaLesegvlswDeLvealtdDiE 42 +++L +g++ ++ L+ +++ ++ FUN_002351-T2 202 VSLL-CKGMYGFEYLLKEVAMHFK 224 5556.7899999999999987665 PP == domain 2 score: 11.4 bits; conditional E-value: 8.7e-05 DUF5805 21 aLesegvlswDeLvealtdDiEdrLde 47 +Le++ v sw +L e+lt D+E++L FUN_002351-T2 443 ILEERKVDSWQQLTEELTLDFEKELIS 469 799999*****************9965 PP >> Lactamase_B Metallo-beta-lactamase superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.4 0.015 76 48 61 .. 30 43 .. 27 51 .. 0.90 2 ? 6.0 0.1 0.0029 15 123 159 .. 110 146 .. 76 171 .. 0.83 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.015 Lactamase_B 48 ilTHgHfDHiGglg 61 +l+H+H DH++gl+ FUN_002351-T2 30 FLSHCHKDHMSGLD 43 79**********96 PP == domain 2 score: 6.0 bits; conditional E-value: 0.0029 Lactamase_B 123 evthtpghgpghvvlydgggkvlftGDllfagetgrl 159 ++++++ g++ + ++ + g+vl+tGD+ ++ ++ + FUN_002351-T2 110 LLPAGHCVGSVMFLFEGQHGNVLYTGDFRLSVGDVKR 146 456778889999****************996665544 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (636 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 720 (0.0281856); expected 510.9 (0.02) Passed bias filter: 632 (0.0247407); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.37s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 6158.28 // Query: FUN_002352-T1 [L=1818] Description: FUN_002352 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.9e-45 153.7 0.6 1.6e-44 152.7 0.6 1.6 1 RhoGEF RhoGEF domain 2e-27 96.2 0.3 2e-12 48.1 0.1 3.2 3 PH PH domain 1.3e-21 76.9 5.4 2.5e-21 76.0 5.4 1.5 1 FYVE FYVE zinc finger 1.1e-07 32.6 0.0 6.3e-05 23.7 0.0 2.7 2 SOS1_NGEF_PH SOS1/NGEF-like PH domain 5.4e-05 24.1 0.0 0.77 10.8 0.0 2.9 2 PH_11 Pleckstrin homology domain 0.0026 18.4 0.0 0.0081 16.8 0.0 1.9 1 RHG20_PH Rho GTPase-activating protein 20, PH domain 0.0057 17.0 0.0 0.013 15.9 0.0 1.5 1 PH_alsin Alsin PH-like domain 0.0076 16.9 1.6 0.0076 16.9 1.6 2.2 2 FYVE_2 FYVE-type zinc finger 0.0098 16.7 0.1 0.2 12.5 0.0 2.9 2 PH_6 Pleckstrin homology domain ------ inclusion threshold ------ 0.01 16.6 0.0 2 9.3 0.0 2.6 2 PH_8 Pleckstrin homology domain 0.012 16.0 0.3 3 8.2 0.1 3.3 2 PH_13 Pleckstrin homology domain 6.9 7.2 8.4 15 6.1 8.4 1.6 1 zf-RING_5 zinc-RING finger domain Domain annotation for each model (and alignments): >> RhoGEF RhoGEF domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 152.7 0.6 7.6e-48 1.6e-44 1 180 [] 1248 1425 .. 1248 1425 .. 0.98 Alignments for each domain: == domain 1 score: 152.7 bits; conditional E-value: 7.6e-48 RhoGEF 1 vikElletEksYvkdLkilvevflkplseeellseeeiktiFsnieeilelhkkllleeLeerlekesseeqkigdvflklaekfkvYseYcsn 94 +++E+l+tE+s+v Lk++ e+ + ++++ ++ ++ + iF ++e+i+ l + +l+eLeer+ ++e+++igd+++k+ +++k+Y++Y++ FUN_002352-T1 1248 IAHEILSTEQSFVAALKLVFEECYGTIKTAGVVADSVLTDIFRDLENIYLLD-SRFLQELEERM-ATWEEHERIGDIIKKYGHFLKMYTQYVNG 1339 689*********************9999888*********************.99*********.99*************************** PP RhoGEF 95 ypkalkllkklkkknkkfkefleelekkpeckgldLeslLikPvqRiprYplLLkellkhtpedhpdyenlkkaleaikevakqin 180 y+ka+ ++++ +k+n++f++++++ + +++c+gl L+s+++kPvqRip Y+lLL ++lkh+p+d ++y ++++al+ ++eva++in FUN_002352-T1 1340 YDKAMGVFQDTMKENSEFANLVTQFQTSKKCHGLVLSSYMLKPVQRIPSYRLLLIDYLKHLPKDGEEYAETETALKIVSEVATHIN 1425 *************************************************************************************9 PP >> PH PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.2 0.1 4 8.4e+03 38 76 .. 574 618 .. 568 624 .. 0.77 2 ! 44.7 0.0 1e-14 2.2e-11 3 104 .. 1459 1549 .. 1457 1550 .. 0.94 3 ! 48.1 0.1 9.2e-16 2e-12 2 104 .. 1723 1814 .. 1722 1815 .. 0.92 Alignments for each domain: == domain 1 score: -2.2 bits; conditional E-value: 4 PH 38 skkskepkgsislkgcevvevva......sdkekrkfvFelrtse 76 + k++++ ++ sl++ +vv+ ++ ++++r++ ++t++ FUN_002352-T1 574 DRKEENLEEVASLSESKVVTEPKaealieGREDNRENNLLVNTNQ 618 4588999999999**999999989999865577777777777664 PP == domain 2 score: 44.7 bits; conditional E-value: 1e-14 PH 3 keGwLlkkgsgkkkswkkryfvLkdgsllyykdkkskkskepkgsislkgcevvevvasdkekrkfvFelrtsertgdrtlllqaeseeerkeW 96 keG+L+k +++ ++r f+L +++lly + ++ ++++ + ++l g +v+ +d+++ + F+++ + +r+++l+a+++eer +W FUN_002352-T1 1459 KEGMLMKLCRK---DMQERMFFLLTDVLLYTTPI-GGNQYKLNKMLPLLGMQVTV---PDSPDLVNEFSIIST----TRSFTLTASTPEERDDW 1541 89*******98...56999999999*********.*******************7...89**********888....6**************** PP PH 97 ikaiqsai 104 i+++++ai FUN_002352-T1 1542 IESLNKAI 1549 *****998 PP == domain 3 score: 48.1 bits; conditional E-value: 9.2e-16 PH 2 vkeGwLlkkgsgkkkswkkryfvLkdgsllyykdkkskkskepkgsislkgcevvevvasdkekrkfvFelrtsertgdrtlllqaeseeerke 95 ++G+L k+ ++ +wkk +fvLkd++l+ yk++ ++ +++++ g+++++ ke+ +fvF+l+++ +++a+ e+++k+ FUN_002352-T1 1723 QMSGYLRYKKLRH--GWKKSWFVLKDSVLYSYKAS---SDVVALETLPVLGYSIED---AGKEGDDFVFQLKHQG---LPPTVFKADQETSAKR 1805 699**99888887..9*******************...*****************9...56**********9983...4889************ PP PH 96 Wikaiqsai 104 Wi+ +++a+ FUN_002352-T1 1806 WIAELKKAT 1814 *****9985 PP >> FYVE FYVE zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 76.0 5.4 1.2e-24 2.5e-21 2 65 .. 1588 1649 .. 1587 1651 .. 0.93 Alignments for each domain: == domain 1 score: 76.0 bits; conditional E-value: 1.2e-24 FYVE 2 wkpdeevkeCseCkkeFtllrrrhHCrkCGkvfCskCsskkislleelkeekpvrvCdeCykkl 65 w+pd++v++C++C+k+Ft ++rrhHCr+CG+v+C +Cs++++ l ++ + ++ rvCd+Cy+ l FUN_002352-T1 1588 WIPDARVTMCMSCTKPFTAINRRHHCRACGNVVCGSCSDSTA-PL-AYLDYTQARVCDKCYDLL 1649 ******************************************.44.589999*********976 PP >> SOS1_NGEF_PH SOS1/NGEF-like PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 3e-08 6.3e-05 10 105 .. 1460 1547 .. 1451 1548 .. 0.85 2 ! 6.0 0.0 0.009 19 52 105 .. 1760 1812 .. 1716 1813 .. 0.69 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 3e-08 SOS1_NGEF_PH 10 qgeltvweeklrkkkkerhvFLFeqlllfckkkkkkkkpsYiyKssiklselgleelvdg.dknkfelwsrekseevyilqakseevkqaWlke 102 +g l + rk +er +FL ++ll++ + ++Y+ + ++l ++++ n+f + s++ ++++l a+++e+++ W++ FUN_002352-T1 1460 EGMLMKLC---RKDMQERMFFLLTDVLLYTTPIG---GNQYKLNKMLPLLGMQVTVPDSPdLVNEFSIISTT---RSFTLTASTPEERDDWIES 1544 55555554...7899*******************...9***********9999886544336999****999...9*****************9 PP SOS1_NGEF_PH 103 ire 105 +++ FUN_002352-T1 1545 LNK 1547 987 PP == domain 2 score: 6.0 bits; conditional E-value: 0.009 SOS1_NGEF_PH 52 yKssiklselgleelvdg.dknkfelwsrekseevyilqakseevkqaWlkeire 105 +++++ +++e+ ++ d+ f+l++++ +++a +e ++W+ e+++ FUN_002352-T1 1760 ALETLPVLGYSIEDAGKEgDDFVFQLKHQG--LPPTVFKADQETSAKRWIAELKK 1812 334555666667775554699999999998..9999****************997 PP >> PH_11 Pleckstrin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.8 0.0 0.00036 0.77 60 100 .. 1510 1547 .. 1504 1548 .. 0.88 2 ! 10.1 0.0 0.00057 1.2 11 100 .. 1730 1812 .. 1724 1813 .. 0.83 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00036 PH_11 60 adknedtlefeistiakskksfflkgenkeekeeWvealke 100 +d+++ ef+i++ ++ sf+l + + ee+ +W+e+l + FUN_002352-T1 1510 PDSPDLVNEFSIISTTR---SFTLTASTPEERDDWIESLNK 1547 67777778999999999...******************987 PP == domain 2 score: 10.1 bits; conditional E-value: 0.00057 PH_11 11 rkgllklwkqrwlilrrkvisLsyYksegalvpegsvvisrkaftlsrradknedtlefeistiakskksfflkgenkeekeeWvealke 100 k+l +wk+ w++l++ v L Yk ++v +++ + +++a k++d+ f+++ + + +k++++ + W+ lk+ FUN_002352-T1 1730 YKKLRHGWKKSWFVLKDSV--LYSYKASSDVVALETLPVLGYS---IEDAGKEGDDFVFQLKHQGL--PPTVFKADQETSAKRWIAELKK 1812 678889*************..*99*988899988877766554...68999999999999999988..6888999999999999999987 PP >> RHG20_PH Rho GTPase-activating protein 20, PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.0 3.8e-06 0.0081 15 92 .. 1471 1542 .. 1458 1543 .. 0.88 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 3.8e-06 RHG20_PH 15 tqerhlfLfsdvLviaklkskksfklkkrvrlselwvascveeveeektsaeksfvlgWpttnvvatFsssevkekWl 92 qer +fL +dvL+ + +++kl+k ++l + v+ + + + f + t + +t s++e++++W+ FUN_002352-T1 1471 MQERMFFLLTDVLLYTTPIGGNQYKLNKMLPLLGMQVTV------PDSPDLVNEFSIISTTRSFTLTASTPEERDDWI 1542 69******************************9999844......456788889999999999999999999999997 PP >> PH_alsin Alsin PH-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 6e-06 0.013 33 105 .. 1468 1550 .. 1460 1555 .. 0.77 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 6e-06 PH_alsin 33 sislssnsFiLFsDvlcq...vggksl...vtyPLstlWvksegelelr....ittPEksfllvtrtseakkvWldqlqssik 105 + + +F L +Dvl + +gg++ ++ PL + v+ ++ +l+ i+ +sf+l++ t+e+++ W+++l+++i FUN_002352-T1 1468 RKDMQERMFFLLTDVLLYttpIGGNQYklnKMLPLLGMQVTVPDSPDLVnefsIISTTRSFTLTASTPEERDDWIESLNKAID 1550 46788899********98333456553111356787788887777666678889999***********************996 PP >> FYVE_2 FYVE-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.5 6.7 1.4e+04 19 45 .. 288 314 .. 286 325 .. 0.73 2 ! 16.9 1.6 3.6e-06 0.0076 54 100 .. 1594 1645 .. 1548 1654 .. 0.87 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 6.7 FYVE_2 19 eelrkkeeeRlgelkeklekesskrel 45 ++l ++eee l+ lk+ +e ++s +l FUN_002352-T1 288 TALSEEEEEELNFLKTSVEVNKSNTHL 314 568889999999999999776665554 PP == domain 2 score: 16.9 bits; conditional E-value: 3.6e-06 FYVE_2 54 ethClrClqpfkllvnskrqCldCklkvCkkCsve......nkkekgwlCkiC 100 t+C+ C++pf+ +n +++C C vC +Cs ++ +C+ C FUN_002352-T1 1594 VTMCMSCTKPFTA-INRRHHCRACGNVVCGSCSDStaplayLDYTQARVCDKC 1645 689********97.58899**************98667766667788888888 PP >> PH_6 Pleckstrin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.5 0.0 9.6e-05 0.2 77 111 .. 1513 1547 .. 1505 1548 .. 0.90 2 ? 0.3 0.0 0.6 1.3e+03 82 111 .. 1782 1812 .. 1766 1813 .. 0.76 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 9.6e-05 PH_6 77 adgeekFhftakGkkhtFkassaaeRdnWvaqlka 111 +d ++F++ + + t as+++eRd+W++ l++ FUN_002352-T1 1513 PDLVNEFSIISTTRSFTLTASTPEERDDWIESLNK 1547 577899************************99876 PP == domain 2 score: 0.3 bits; conditional E-value: 0.6 PH_6 82 kFhftakGkk.htFkassaaeRdnWvaqlka 111 F+++ +G Fka + + +W+a+lk+ FUN_002352-T1 1782 VFQLKHQGLPpTVFKADQETSAKRWIAELKK 1812 4677777764267***************997 PP >> PH_8 Pleckstrin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.00093 2 1 88 [. 1461 1548 .. 1461 1549 .. 0.75 2 ? 4.5 0.1 0.028 60 8 87 .. 1731 1812 .. 1727 1814 .. 0.69 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00093 PH_8 1 gillkkrrkklqgyakRfFvLdlkestlsYyrddnss...klrgkipislaiisanae...sreiiidsGaevWnLkarnekdfqeWvdaleki 88 g+l+k rk +q+ + fF L +++ y++ ++ kl +p+ + + ++ e++i s ++ ++L a+ ++ + W+++l+k+ FUN_002352-T1 1461 GMLMKLCRKDMQE--RMFFLL----TDVLLYTTPIGGnqyKLNKMLPLLGMQVTVPDSpdlVNEFSIISTTRSFTLTASTPEERDDWIESLNKA 1548 7899999**9999..777777....555555554322245898889987665555443112689***************************986 PP == domain 2 score: 4.5 bits; conditional E-value: 0.028 PH_8 8 rkklqgyakRfFvLdlkestlsYyrddnssklrgkipi.slaiisanaesreiiid...sGaevWnLkarnekdfqeWvdalek 87 +k +g++k +FvL k s l y+ + + + +p+ +i +a +e +++ + G ka++e+ +++W+ l+k FUN_002352-T1 1731 KKLRHGWKKSWFVL--KDSVLYSYKASSDVVALETLPVlGYSIEDAGKEGDDFVFQlkhQGLPPTVFKADQETSAKRWIAELKK 1812 56678*********..99999999988887555777761455667777777766542225666666777777777777776665 PP >> PH_13 Pleckstrin homology domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.1 0.0014 3 72 131 .. 1492 1549 .. 1440 1564 .. 0.73 2 ? 2.9 0.0 0.059 1.3e+02 95 131 .. 1777 1814 .. 1736 1816 .. 0.76 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0014 PH_13 72 lqyklYkk.piflnevlvkeptdvsseeptfqishidrvytlkaesinertaWvkkikeaa 131 qykl k p+ +v+v ++ d + f+i + r +tl a++++er W++ +++a FUN_002352-T1 1492 NQYKLNKMlPLLGMQVTVPDSPDLV---NEFSIISTTRSFTLTASTPEERDDWIESLNKAI 1549 4566655335555555555555554...67899999999*****************99996 PP == domain 2 score: 2.9 bits; conditional E-value: 0.059 PH_13 95 sseeptfqishidr.vytlkaesinertaWvkkikeaa 131 ++ +fq++h + ++ka++ + ++W+ +k+a+ FUN_002352-T1 1777 EGDDFVFQLKHQGLpPTVFKADQETSAKRWIAELKKAT 1814 3677799999987625899*****************97 PP >> zf-RING_5 zinc-RING finger domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 8.4 0.0071 15 2 41 .. 1597 1645 .. 1596 1649 .. 0.88 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0071 zf-RING_5 2 CnkCfkel.sktrkfyltsCgHifCeeClkkll........eerqCpiC 41 C +C k++ +r+ + +Cg ++C +C + + + r+C C FUN_002352-T1 1597 CMSCTKPFtAINRRHHCRACGNVVCGSCSDSTAplayldytQARVCDKC 1645 99******99999***************999988888888877777655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1818 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1199 (0.0469368); expected 510.9 (0.02) Passed bias filter: 532 (0.020826); expected 510.9 (0.02) Passed Vit filter: 59 (0.00230965); expected 25.5 (0.001) Passed Fwd filter: 14 (0.000548052); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.53u 0.43s 00:00:00.96 Elapsed: 00:00:00.43 # Mc/sec: 17096.25 // Query: FUN_002354-T1 [L=1024] Description: FUN_002354 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-13 52.0 0.0 2.1e-13 51.0 0.0 1.5 1 ResIII Type III restriction enzyme, res subunit 8.9e-13 48.8 0.0 2.3e-12 47.5 0.0 1.7 1 DEAD DEAD/DEAH box helicase 6.7e-09 36.2 12.9 3.1e-05 24.5 1.8 2.9 2 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding 4.5e-08 33.6 11.7 0.0019 18.9 3.4 2.9 2 zf-met Zinc-finger of C2H2 type 7.8e-05 22.9 8.8 0.0083 16.4 1.4 2.8 2 zf-U1 U1 zinc finger 0.00013 22.6 0.0 0.00068 20.3 0.0 2.3 2 Helicase_C Helicase conserved C-terminal domain 0.0066 17.1 6.9 0.58 10.9 0.2 3.1 3 zf-C2H2_2 C2H2 type zinc-finger (2 copies) ------ inclusion threshold ------ 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 SWI2_SNF2 SWI2/SNF2 ATPase 0.058 13.7 0.0 0.18 12.1 0.0 1.9 2 TrmB Sugar-specific transcriptional regulator Tr 0.1 13.2 0.0 0.43 11.2 0.0 2.1 1 z-alpha Adenosine deaminase z-alpha domain 0.17 12.1 0.8 10 6.4 0.1 2.5 2 zf-C2H2_OTU1_C Ubiquitin thioesterase OTU1, C-terminal C2H 0.2 11.6 0.0 0.55 10.2 0.0 1.7 2 PhoH PhoH-like protein 0.28 12.3 5.8 0.9 10.7 5.8 1.9 1 Zf-C2H2_ZNF451_C Two consecutive Zinc fingers C2H2 type, ZNF 2.6 8.6 10.4 2.3 8.8 1.1 2.6 2 zf-DBF DBF zinc finger 3.3 8.8 8.9 0.81 10.8 1.1 3.3 2 zf-C2H2 Zinc finger, C2H2 type 9.3 7.8 5.9 8.2 8.0 0.4 3.3 2 zf-C2H2_4 C2H2-type zinc finger Domain annotation for each model (and alignments): >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.0 0.0 1.3e-16 2.1e-13 25 162 .. 503 665 .. 485 667 .. 0.72 Alignments for each domain: == domain 1 score: 51.0 bits; conditional E-value: 1.3e-16 ResIII 25 rglivmaTGsGKTlvaakliarlskkgkekkvlflvdrkeLleqakeefkkflseekke...ageilsgdkkke...............ekkekki 102 + + ++TGsGKTlvaa +ia++ k + ++v+flvdr L+ q + +++ ls + + +++ ++g + + + e+++ FUN_002354-T1 503 NSVCFLPTGSGKTLVAALVIAHMLKLNPCRQVVFLVDRVLLVLQQSDYLRSELSHIRVAdegSSNSFNGTRPIRigavcgemrklegnsRIYEQDV 598 455669****************************************88866555544333332233333333334555555555555546669999 PP ResIII 103 vvttiqslskalekekeellkdkfdviiiDEaHrsaakksyrkileyf.........kaafllglTATp 162 +++t + ++l ++ l + +i+ DEaH+ ++++ y+ i+ f ++ +lglTA p FUN_002354-T1 599 LIITADCYRNHL--NNGTLRFEDVSLIVLDEAHHCNKDHPYNVIIRDFylreddllgHRPKVLGLTASP 665 999999999999..77777778888************9999999777756554455555999****988 PP >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.5 0.0 1.4e-15 2.3e-12 3 161 .. 491 666 .. 489 670 .. 0.78 Alignments for each domain: == domain 1 score: 47.5 bits; conditional E-value: 1.4e-15 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxx RF DEAD 3 iQaeaipallegkdvlvqapTGsGKTlafllpilealkkkkegpqalvlaPtreLaeqiveelkkllk...............klglkvasllggd 83 +Q+e + +++ + ++ pTGsGKTl+++l i + l k ++ q+++l+ L+ q+ + l++ l+ +++ +++g FUN_002354-T1 491 YQRELYGKAM-TANSVCFLPTGSGKTLVAALVIAHML-KLNPCRQVVFLVDRVLLVLQQSDYLRSELShirvadegssnsfngTRPIRIGAVCGEM 584 5677777777.45778889***************999.689999*******************999997777777776655422338888888999 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxx RF DEAD 84 srkeqleklkkadilvgtpgrlldlleerkk..lknlkllvlDEahrlldkgfgeqleeilrrlk......lpkkrqilllSATlp 161 ++ e +++ + d+l+ t + ++l ++++ +++++l+vlDEah ++++ ++ i+r + l + ++l+l+A ++ FUN_002354-T1 585 RKLEGNSRIYEQDVLIITADCYRNHL-NNGTlrFEDVSLIVLDEAHHCNKD---HPYNVIIRDFYlreddlLGHRPKVLGLTASPA 666 99999999999***************.445568***************999...55555555555445565333456888888775 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 1.8 1.9e-08 3.1e-05 1 27 [] 390 416 .. 390 416 .. 0.96 2 ! 16.1 3.7 8.6e-06 0.014 3 26 .. 430 453 .. 428 453 .. 0.95 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.9e-08 zf-C2H2_jaz 1 qfYCvlCdKyFksenalqnHlkSKkHK 27 +++C++C+ F s+ ++++Hl+S kH+ FUN_002354-T1 390 PYFCKYCKLPFQSAAQFEEHLQSTKHQ 416 59************************6 PP == domain 2 score: 16.1 bits; conditional E-value: 8.6e-06 zf-C2H2_jaz 3 YCvlCdKyFksenalqnHlkSKkH 26 +C++C+ + +se++ ++H++S H FUN_002354-T1 430 FCEYCKVHLNSESQAKEHFNSGRH 453 8********************988 PP >> zf-met Zinc-finger of C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 1.3 1.3e-06 0.002 1 25 [] 391 415 .. 391 415 .. 0.98 2 ! 18.9 3.4 1.2e-06 0.0019 2 25 .] 430 453 .. 429 453 .. 0.96 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 1.3e-06 zf-met 1 fyCelCnvtftsesqlksHlqGKkH 25 ++C+ C+ f+s +q++ Hlq+ kH FUN_002354-T1 391 YFCKYCKLPFQSAAQFEEHLQSTKH 415 89**********************9 PP == domain 2 score: 18.9 bits; conditional E-value: 1.2e-06 zf-met 2 yCelCnvtftsesqlksHlqGKkH 25 +Ce C+v ++sesq+k H ++ +H FUN_002354-T1 430 FCEYCKVHLNSESQAKEHFNSGRH 453 8**********************9 PP >> zf-U1 U1 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 1.1 0.00059 0.94 4 37 .. 391 422 .. 388 423 .. 0.80 2 ! 16.4 1.4 5.2e-06 0.0083 3 35 .. 428 458 .. 427 460 .. 0.81 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00059 zf-U1 4 YyCdYCdiyLthDspsvRksHngGrkHkenvkdy 37 Y+C+YC+ + + H + kH++ ++y FUN_002354-T1 391 YFCKYCKLPFQSAA-QF-EEHLQSTKHQNKYAKY 422 *******9984444.33.7999999999988887 PP == domain 2 score: 16.4 bits; conditional E-value: 5.2e-06 zf-U1 3 kYyCdYCdiyLthDspsvRksHngGrkHkenvk 35 +++C+YC++ L ++ ++ k H + H + v+ FUN_002354-T1 428 RKFCEYCKVHL-NSESQA-KEHFNSGRHEQTVA 458 89*********.444467.99988888998887 PP >> Helicase_C Helicase conserved C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 8 1.3e+04 69 83 .. 268 282 .. 256 289 .. 0.78 2 ! 20.3 0.0 4.3e-07 0.00068 18 106 .. 885 987 .. 864 991 .. 0.74 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 8 Helicase_C 69 LvatdvaerGldlpd 83 Lva d+a G+d +d FUN_002354-T1 268 LVAGDIATLGVDTED 282 9999********875 PP == domain 2 score: 20.3 bits; conditional E-value: 4.3e-07 Helicase_C 18 vlifvqtkkelel.aell.....lekegikvarlhgd.lsqeere.......eilekfrkgkikvLvatdvaerGldlpdvdlvinydlpwnpasy 99 vl+ v++k+++ + a++l l+ +gi+ ++l + + e++ e+l++ +g ++++v+t++ e +l lp+++lv+++++p++++ + FUN_002354-T1 885 VLVLVTRKRTASHlANYLssspqLQARGITSVCLKDQgSGSGEQDlvafepgEVLQRICDGFVQIVVSTSAPEDSLGLPSCQLVVQMNPPSSTQAL 980 67777777777666677755543333366666666552222222244455558999999999********************************** PP Helicase_C 100 iQriGRa 106 Q++ R FUN_002354-T1 981 TQIRARS 987 ***9995 PP >> zf-C2H2_2 C2H2 type zinc-finger (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.9 0.2 0.00036 0.58 51 78 .. 391 418 .. 384 430 .. 0.85 2 ! 7.8 1.7 0.0033 5.3 50 83 .. 428 461 .. 418 470 .. 0.83 3 ? -2.7 0.0 6.4 1e+04 5 29 .. 716 741 .. 713 749 .. 0.75 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00036 zf-C2H2_2 51 leClvCekefkslealreHmkdkgHcki 78 C +C+ f+s ++++eH+++ +H + FUN_002354-T1 391 YFCKYCKLPFQSAAQFEEHLQSTKHQNK 418 57***********************874 PP == domain 2 score: 7.8 bits; conditional E-value: 0.0033 zf-C2H2_2 50 kleClvCekefkslealreHmkdkgHckiayeee 83 ++ C +C+ + +s ++ +eH ++ +H + +++ FUN_002354-T1 428 RKFCEYCKVHLNSESQAKEHFNSGRHEQTVAKSQ 461 568***********************99866554 PP == domain 3 score: -2.7 bits; conditional E-value: 6.4 zf-C2H2_2 5 cekeske.veenlehmskkhglfipe 29 c+ ++e ++++e+++k+++l ++ FUN_002354-T1 716 CTPPEEElRDALMEYVTKAFNLTVRL 741 55555666899999***999999874 PP >> SWI2_SNF2 SWI2/SNF2 ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 1.5e-05 0.024 20 110 .. 503 612 .. 483 678 .. 0.69 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.5e-05 SWI2_SNF2 20 gGviWHtqGSGKsltmvflakklleelknpkvvvvtDRkdLdkQlsktfkkageeepk.qaesrkeLkellkesekiifttiqKfe.kee..ek.. 109 + v + +GSGK+l +++ +l+ + +vv+++DR L Q s+ +++ ++ + + s+++++ + + + ++ + K+e +++ e+ FUN_002354-T1 503 NSVCFLPTGSGKTLVAALVIAHMLKLNPCRQVVFLVDRVLLVLQQSDYLRSELSHIRVaDEGSSNSFNGTRPIRIGAVCGEMRKLEgNSRiyEQdv 598 56667779*****************999*************9999988887644432203333333333332256666666666652111221134 PP SWI2_SNF2 110 .............l 110 FUN_002354-T1 599 liitadcyrnhlnN 612 44444444443322 PP >> TrmB Sugar-specific transcriptional regulator TrmB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00012 0.18 10 65 .. 255 310 .. 248 312 .. 0.86 2 ? -3.4 0.2 7.9 1.3e+04 55 67 .. 415 427 .. 413 428 .. 0.78 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00012 TrmB 10 EakvYlaLlklgpatadeiaeesgvp.rskvYevLrsLedkGlVerekgrpklYrav 65 E +++ L ++gp+ a +ia +gv+ + +v+ L L ++GlVe++ ++p lY + FUN_002354-T1 255 EKRIFELLRNNGPLVAGDIAT-LGVDtEDRVNHCLFTLYRRGLVEISGSSPPLYAVS 310 7788888889*********97.5665278*************************875 PP == domain 2 score: -3.4 bits; conditional E-value: 7.9 TrmB 55 ekgrpklYravdp 67 + ++ +Y+av++ FUN_002354-T1 415 HQNKYAKYNAVPY 427 567799*****96 PP >> z-alpha Adenosine deaminase z-alpha domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00027 0.43 6 65 .. 255 311 .. 252 312 .. 0.85 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00027 z-alpha 6 aekilelLeelgekkaatalalergLstpkreiNrvLydlerkgkvyredgtPPlWfltt 65 +++i elL++ g a +a ++g+ t+ r +N L+ l r+g v ++ PPl + + FUN_002354-T1 255 EKRIFELLRNNG-PLVAGDIA-TLGVDTEDR-VNHCLFTLYRRGLVEISGSSPPLYAVSD 311 678999999999.66666666.689998655.***********************98865 PP >> zf-C2H2_OTU1_C Ubiquitin thioesterase OTU1, C-terminal C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.047 75 7 31 .. 393 417 .. 392 417 .. 0.92 2 ? 6.4 0.1 0.0065 10 7 23 .. 431 447 .. 430 453 .. 0.91 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.047 zf-C2H2_OTU1_C 7 CgvCqkglkGekeAveHAkaTGHtn 31 C+ C+ ++ + eH ++T H+n FUN_002354-T1 393 CKYCKLPFQSAAQFEEHLQSTKHQN 417 999999999999999********98 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0065 zf-C2H2_OTU1_C 7 CgvCqkglkGekeAveH 23 C+ C++ l e +A eH FUN_002354-T1 431 CEYCKVHLNSESQAKEH 447 ***************** PP >> PhoH PhoH-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.00034 0.55 5 54 .. 489 536 .. 485 543 .. 0.84 2 ? -3.2 0.0 4.2 6.7e+03 121 136 .. 621 636 .. 619 642 .. 0.74 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00034 PhoH 5 ktaeQkeyvealkkndivfaiGpaGtGKtylavalavealkekkvkriil 54 + + + y +a+++n+++f p+G+GKt++a + +++lk + ++++++ FUN_002354-T1 489 YSYQRELYGKAMTANSVCFL--PTGSGKTLVAALVIAHMLKLNPCRQVVF 536 56667778899999999887..9*****************9999999886 PP == domain 2 score: -3.2 bits; conditional E-value: 4.2 PhoH 121 afvilDeaQnttkeqm 136 ++++lDea ++k + FUN_002354-T1 621 SLIVLDEAHHCNKDHP 636 79******98887765 PP >> Zf-C2H2_ZNF451_C Two consecutive Zinc fingers C2H2 type, ZNF451 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 5.8 0.00056 0.9 3 58 .. 391 448 .. 390 449 .. 0.82 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00056 Zf-C2H2_ZNF451_C 3 FrCslCsaTaQnladlnaHlekahsekkkee..eemyvvkCgaCskafsdlesAqqHy 58 + C C+ Q+ a+ ++Hl+++++++k + + y C C+ + ++ ++A++H+ FUN_002354-T1 391 YFCKYCKLPFQSAAQFEEHLQSTKHQNKYAKynAVPYRKFCEYCKVHLNSESQAKEHF 448 77******************99877665444004456667*****************9 PP >> zf-DBF DBF zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.8 1.1 0.0014 2.3 5 27 .. 392 417 .. 389 425 .. 0.77 2 ? 4.0 2.5 0.046 73 5 29 .. 430 457 .. 426 462 .. 0.76 Alignments for each domain: == domain 1 score: 8.8 bits; conditional E-value: 0.0014 zf-DBF 5 YCEnCrekfe...dleeHiesekHrk 27 +C C+ f+ ++eeH++s kH++ FUN_002354-T1 392 FCKYCKLPFQsaaQFEEHLQSTKHQN 417 788899888633369*********95 PP == domain 2 score: 4.0 bits; conditional E-value: 0.046 zf-DBF 5 YCEnCrekfe...dleeHiesekHrkFa 29 +CE C+++ + + +eH +s +H + + FUN_002354-T1 430 FCEYCKVHLNsesQAKEHFNSGRHEQTV 457 9******9972225789*******8755 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 1.1 0.00051 0.81 1 22 [. 391 412 .. 391 415 .. 0.90 2 ? 0.6 1.4 0.89 1.4e+03 3 22 .. 431 450 .. 430 453 .. 0.87 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00051 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrt 22 y C++C+ F ++ +++ Hl++ FUN_002354-T1 391 YFCKYCKLPFQSAAQFEEHLQS 412 88*****************987 PP == domain 2 score: 0.6 bits; conditional E-value: 0.89 zf-C2H2 3 CpdCgksFsrksnLkrHlrt 22 C++C+ ++ s+ k H ++ FUN_002354-T1 431 CEYCKVHLNSESQAKEHFNS 450 *************9999876 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.4 0.0051 8.2 1 21 [. 391 411 .. 391 413 .. 0.92 2 ? 0.5 0.8 1.2 2e+03 3 20 .. 431 448 .. 429 450 .. 0.78 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.0051 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlk 21 + C++C+ +F s ++ Hl+ FUN_002354-T1 391 YFCKYCKLPFQSAAQFEEHLQ 411 78*****************97 PP == domain 2 score: 0.5 bits; conditional E-value: 1.2 zf-C2H2_4 3 CpiCgksFsskkaLrrHl 20 C++C+ +s ++ + H+ FUN_002354-T1 431 CEYCKVHLNSESQAKEHF 448 ****99998888777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1024 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 963 (0.0376982); expected 510.9 (0.02) Passed bias filter: 787 (0.0308084); expected 510.9 (0.02) Passed Vit filter: 82 (0.00321002); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.43u 0.40s 00:00:00.83 Elapsed: 00:00:00.42 # Mc/sec: 9757.19 // Query: FUN_002354-T2 [L=1008] Description: FUN_002354 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1e-13 52.0 0.0 2.1e-13 51.0 0.0 1.5 1 ResIII Type III restriction enzyme, res subunit 8.7e-13 48.8 0.0 2.2e-12 47.5 0.0 1.7 1 DEAD DEAD/DEAH box helicase 6.4e-09 36.2 12.9 3e-05 24.5 1.8 2.9 2 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding 4.3e-08 33.7 11.7 0.0019 19.0 3.4 2.9 2 zf-met Zinc-finger of C2H2 type 7.5e-05 22.9 8.8 0.0081 16.4 1.4 2.8 2 zf-U1 U1 zinc finger 0.00013 22.7 0.0 0.00067 20.4 0.0 2.3 2 Helicase_C Helicase conserved C-terminal domain 0.0063 17.2 6.9 0.57 10.9 0.2 3.1 3 zf-C2H2_2 C2H2 type zinc-finger (2 copies) ------ inclusion threshold ------ 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 SWI2_SNF2 SWI2/SNF2 ATPase 0.056 13.8 0.0 0.18 12.2 0.0 1.9 2 TrmB Sugar-specific transcriptional regulator Tr 0.097 13.2 0.0 0.42 11.2 0.0 2.1 1 z-alpha Adenosine deaminase z-alpha domain 0.16 12.2 0.8 10 6.4 0.1 2.5 2 zf-C2H2_OTU1_C Ubiquitin thioesterase OTU1, C-terminal C2H 0.19 11.6 0.0 0.54 10.2 0.0 1.7 2 PhoH PhoH-like protein 0.27 12.3 5.8 0.88 10.7 5.8 1.9 1 Zf-C2H2_ZNF451_C Two consecutive Zinc fingers C2H2 type, ZNF 2.5 8.7 10.4 2.2 8.9 1.1 2.6 2 zf-DBF DBF zinc finger 3.1 8.9 8.9 0.8 10.8 1.1 3.3 2 zf-C2H2 Zinc finger, C2H2 type 8.9 7.8 5.9 8 8.0 0.4 3.3 2 zf-C2H2_4 C2H2-type zinc finger Domain annotation for each model (and alignments): >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.0 0.0 1.3e-16 2.1e-13 25 162 .. 487 649 .. 469 651 .. 0.72 Alignments for each domain: == domain 1 score: 51.0 bits; conditional E-value: 1.3e-16 ResIII 25 rglivmaTGsGKTlvaakliarlskkgkekkvlflvdrkeLleqakeefkkflseekke...ageilsgdkkke...............ekkekki 102 + + ++TGsGKTlvaa +ia++ k + ++v+flvdr L+ q + +++ ls + + +++ ++g + + + e+++ FUN_002354-T2 487 NSVCFLPTGSGKTLVAALVIAHMLKLNPCRQVVFLVDRVLLVLQQSDYLRSELSHIRVAdegSSNSFNGTRPIRigavcgemrklegnsRIYEQDV 582 455669****************************************88866555544333332233333333334555555555555546669999 PP ResIII 103 vvttiqslskalekekeellkdkfdviiiDEaHrsaakksyrkileyf.........kaafllglTATp 162 +++t + ++l ++ l + +i+ DEaH+ ++++ y+ i+ f ++ +lglTA p FUN_002354-T2 583 LIITADCYRNHL--NNGTLRFEDVSLIVLDEAHHCNKDHPYNVIIRDFylreddllgHRPKVLGLTASP 649 999999999999..77777778888************9999999777756554455555999****988 PP >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.5 0.0 1.4e-15 2.2e-12 3 161 .. 475 650 .. 473 654 .. 0.78 Alignments for each domain: == domain 1 score: 47.5 bits; conditional E-value: 1.4e-15 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxx RF DEAD 3 iQaeaipallegkdvlvqapTGsGKTlafllpilealkkkkegpqalvlaPtreLaeqiveelkkllk...............klglkvasllggd 83 +Q+e + +++ + ++ pTGsGKTl+++l i + l k ++ q+++l+ L+ q+ + l++ l+ +++ +++g FUN_002354-T2 475 YQRELYGKAM-TANSVCFLPTGSGKTLVAALVIAHML-KLNPCRQVVFLVDRVLLVLQQSDYLRSELShirvadegssnsfngTRPIRIGAVCGEM 568 5677777777.45778889***************999.689999*******************999997777777776655422338888888999 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxx RF DEAD 84 srkeqleklkkadilvgtpgrlldlleerkk..lknlkllvlDEahrlldkgfgeqleeilrrlk......lpkkrqilllSATlp 161 ++ e +++ + d+l+ t + ++l ++++ +++++l+vlDEah ++++ ++ i+r + l + ++l+l+A ++ FUN_002354-T2 569 RKLEGNSRIYEQDVLIITADCYRNHL-NNGTlrFEDVSLIVLDEAHHCNKD---HPYNVIIRDFYlreddlLGHRPKVLGLTASPA 650 99999999999***************.445568***************999...55555555555445565333456888888775 PP >> zf-C2H2_jaz Zinc-finger double-stranded RNA-binding # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.5 1.8 1.9e-08 3e-05 1 27 [] 374 400 .. 374 400 .. 0.96 2 ! 16.1 3.7 8.4e-06 0.013 3 26 .. 414 437 .. 412 437 .. 0.95 Alignments for each domain: == domain 1 score: 24.5 bits; conditional E-value: 1.9e-08 zf-C2H2_jaz 1 qfYCvlCdKyFksenalqnHlkSKkHK 27 +++C++C+ F s+ ++++Hl+S kH+ FUN_002354-T2 374 PYFCKYCKLPFQSAAQFEEHLQSTKHQ 400 59************************6 PP == domain 2 score: 16.1 bits; conditional E-value: 8.4e-06 zf-C2H2_jaz 3 YCvlCdKyFksenalqnHlkSKkH 26 +C++C+ + +se++ ++H++S H FUN_002354-T2 414 FCEYCKVHLNSESQAKEHFNSGRH 437 8********************988 PP >> zf-met Zinc-finger of C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 1.3 1.2e-06 0.002 1 25 [] 375 399 .. 375 399 .. 0.98 2 ! 19.0 3.4 1.2e-06 0.0019 2 25 .] 414 437 .. 413 437 .. 0.96 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 1.2e-06 zf-met 1 fyCelCnvtftsesqlksHlqGKkH 25 ++C+ C+ f+s +q++ Hlq+ kH FUN_002354-T2 375 YFCKYCKLPFQSAAQFEEHLQSTKH 399 89**********************9 PP == domain 2 score: 19.0 bits; conditional E-value: 1.2e-06 zf-met 2 yCelCnvtftsesqlksHlqGKkH 25 +Ce C+v ++sesq+k H ++ +H FUN_002354-T2 414 FCEYCKVHLNSESQAKEHFNSGRH 437 8**********************9 PP >> zf-U1 U1 zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 1.1 0.00058 0.93 4 37 .. 375 406 .. 372 407 .. 0.80 2 ! 16.4 1.4 5.1e-06 0.0081 3 35 .. 412 442 .. 411 444 .. 0.81 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00058 zf-U1 4 YyCdYCdiyLthDspsvRksHngGrkHkenvkdy 37 Y+C+YC+ + + H + kH++ ++y FUN_002354-T2 375 YFCKYCKLPFQSAA-QF-EEHLQSTKHQNKYAKY 406 *******9984444.33.7999999999988887 PP == domain 2 score: 16.4 bits; conditional E-value: 5.1e-06 zf-U1 3 kYyCdYCdiyLthDspsvRksHngGrkHkenvk 35 +++C+YC++ L ++ ++ k H + H + v+ FUN_002354-T2 412 RKFCEYCKVHL-NSESQA-KEHFNSGRHEQTVA 442 89*********.444467.99988888998887 PP >> Helicase_C Helicase conserved C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 7.9 1.3e+04 69 83 .. 252 266 .. 240 273 .. 0.78 2 ! 20.4 0.0 4.2e-07 0.00067 18 106 .. 869 971 .. 848 975 .. 0.74 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 7.9 Helicase_C 69 LvatdvaerGldlpd 83 Lva d+a G+d +d FUN_002354-T2 252 LVAGDIATLGVDTED 266 9999********875 PP == domain 2 score: 20.4 bits; conditional E-value: 4.2e-07 Helicase_C 18 vlifvqtkkelel.aell.....lekegikvarlhgd.lsqeere.......eilekfrkgkikvLvatdvaerGldlpdvdlvinydlpwnpasy 99 vl+ v++k+++ + a++l l+ +gi+ ++l + + e++ e+l++ +g ++++v+t++ e +l lp+++lv+++++p++++ + FUN_002354-T2 869 VLVLVTRKRTASHlANYLssspqLQARGITSVCLKDQgSGSGEQDlvafepgEVLQRICDGFVQIVVSTSAPEDSLGLPSCQLVVQMNPPSSTQAL 964 67777777777666677755543333366666666552222222244455558999999999********************************** PP Helicase_C 100 iQriGRa 106 Q++ R FUN_002354-T2 965 TQIRARS 971 ***9995 PP >> zf-C2H2_2 C2H2 type zinc-finger (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.9 0.2 0.00036 0.57 51 78 .. 375 402 .. 368 414 .. 0.85 2 ! 7.9 1.7 0.0033 5.2 50 83 .. 412 445 .. 402 454 .. 0.83 3 ? -2.7 0.0 6.3 1e+04 5 29 .. 700 725 .. 697 733 .. 0.75 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 0.00036 zf-C2H2_2 51 leClvCekefkslealreHmkdkgHcki 78 C +C+ f+s ++++eH+++ +H + FUN_002354-T2 375 YFCKYCKLPFQSAAQFEEHLQSTKHQNK 402 57***********************874 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0033 zf-C2H2_2 50 kleClvCekefkslealreHmkdkgHckiayeee 83 ++ C +C+ + +s ++ +eH ++ +H + +++ FUN_002354-T2 412 RKFCEYCKVHLNSESQAKEHFNSGRHEQTVAKSQ 445 568***********************99866554 PP == domain 3 score: -2.7 bits; conditional E-value: 6.3 zf-C2H2_2 5 cekeske.veenlehmskkhglfipe 29 c+ ++e ++++e+++k+++l ++ FUN_002354-T2 700 CTPPEEElRDALMEYVTKAFNLTVRL 725 55555666899999***999999874 PP >> SWI2_SNF2 SWI2/SNF2 ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 1.5e-05 0.023 20 110 .. 487 596 .. 466 662 .. 0.69 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.5e-05 SWI2_SNF2 20 gGviWHtqGSGKsltmvflakklleelknpkvvvvtDRkdLdkQlsktfkkageeepk.qaesrkeLkellkesekiifttiqKfe.kee..ek.. 109 + v + +GSGK+l +++ +l+ + +vv+++DR L Q s+ +++ ++ + + s+++++ + + + ++ + K+e +++ e+ FUN_002354-T2 487 NSVCFLPTGSGKTLVAALVIAHMLKLNPCRQVVFLVDRVLLVLQQSDYLRSELSHIRVaDEGSSNSFNGTRPIRIGAVCGEMRKLEgNSRiyEQdv 582 56667779*****************999*************9999988887644432203333333333332256666666666652111221134 PP SWI2_SNF2 110 .............l 110 FUN_002354-T2 583 liitadcyrnhlnN 596 44444444443322 PP >> TrmB Sugar-specific transcriptional regulator TrmB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00011 0.18 10 65 .. 239 294 .. 232 296 .. 0.86 2 ? -3.3 0.2 7.8 1.2e+04 55 67 .. 399 411 .. 397 412 .. 0.78 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00011 TrmB 10 EakvYlaLlklgpatadeiaeesgvp.rskvYevLrsLedkGlVerekgrpklYrav 65 E +++ L ++gp+ a +ia +gv+ + +v+ L L ++GlVe++ ++p lY + FUN_002354-T2 239 EKRIFELLRNNGPLVAGDIAT-LGVDtEDRVNHCLFTLYRRGLVEISGSSPPLYAVS 294 7788888889*********97.5665278*************************875 PP == domain 2 score: -3.3 bits; conditional E-value: 7.8 TrmB 55 ekgrpklYravdp 67 + ++ +Y+av++ FUN_002354-T2 399 HQNKYAKYNAVPY 411 567799*****96 PP >> z-alpha Adenosine deaminase z-alpha domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.00026 0.42 6 65 .. 239 295 .. 236 296 .. 0.85 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00026 z-alpha 6 aekilelLeelgekkaatalalergLstpkreiNrvLydlerkgkvyredgtPPlWfltt 65 +++i elL++ g a +a ++g+ t+ r +N L+ l r+g v ++ PPl + + FUN_002354-T2 239 EKRIFELLRNNG-PLVAGDIA-TLGVDTEDR-VNHCLFTLYRRGLVEISGSSPPLYAVSD 295 678999999999.66666666.689998655.***********************98865 PP >> zf-C2H2_OTU1_C Ubiquitin thioesterase OTU1, C-terminal C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.0 0.046 73 7 31 .. 377 401 .. 376 401 .. 0.92 2 ? 6.4 0.1 0.0064 10 7 23 .. 415 431 .. 414 437 .. 0.91 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.046 zf-C2H2_OTU1_C 7 CgvCqkglkGekeAveHAkaTGHtn 31 C+ C+ ++ + eH ++T H+n FUN_002354-T2 377 CKYCKLPFQSAAQFEEHLQSTKHQN 401 999999999999999********98 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0064 zf-C2H2_OTU1_C 7 CgvCqkglkGekeAveH 23 C+ C++ l e +A eH FUN_002354-T2 415 CEYCKVHLNSESQAKEH 431 ***************** PP >> PhoH PhoH-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.00034 0.54 5 54 .. 473 520 .. 469 527 .. 0.84 2 ? -3.2 0.0 4.2 6.6e+03 121 136 .. 605 620 .. 603 626 .. 0.74 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00034 PhoH 5 ktaeQkeyvealkkndivfaiGpaGtGKtylavalavealkekkvkriil 54 + + + y +a+++n+++f p+G+GKt++a + +++lk + ++++++ FUN_002354-T2 473 YSYQRELYGKAMTANSVCFL--PTGSGKTLVAALVIAHMLKLNPCRQVVF 520 56667778899999999887..9*****************9999999886 PP == domain 2 score: -3.2 bits; conditional E-value: 4.2 PhoH 121 afvilDeaQnttkeqm 136 ++++lDea ++k + FUN_002354-T2 605 SLIVLDEAHHCNKDHP 620 79******98887765 PP >> Zf-C2H2_ZNF451_C Two consecutive Zinc fingers C2H2 type, ZNF451 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 5.8 0.00055 0.88 3 58 .. 375 432 .. 374 433 .. 0.82 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00055 Zf-C2H2_ZNF451_C 3 FrCslCsaTaQnladlnaHlekahsekkkee..eemyvvkCgaCskafsdlesAqqHy 58 + C C+ Q+ a+ ++Hl+++++++k + + y C C+ + ++ ++A++H+ FUN_002354-T2 375 YFCKYCKLPFQSAAQFEEHLQSTKHQNKYAKynAVPYRKFCEYCKVHLNSESQAKEHF 432 77******************99877665444004456667*****************9 PP >> zf-DBF DBF zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.9 1.1 0.0014 2.2 5 27 .. 376 401 .. 373 409 .. 0.77 2 ? 4.0 2.5 0.045 72 5 29 .. 414 441 .. 410 446 .. 0.76 Alignments for each domain: == domain 1 score: 8.9 bits; conditional E-value: 0.0014 zf-DBF 5 YCEnCrekfe...dleeHiesekHrk 27 +C C+ f+ ++eeH++s kH++ FUN_002354-T2 376 FCKYCKLPFQsaaQFEEHLQSTKHQN 401 788899888633369*********95 PP == domain 2 score: 4.0 bits; conditional E-value: 0.045 zf-DBF 5 YCEnCrekfe...dleeHiesekHrkFa 29 +CE C+++ + + +eH +s +H + + FUN_002354-T2 414 FCEYCKVHLNsesQAKEHFNSGRHEQTV 441 9******9972225789*******8755 PP >> zf-C2H2 Zinc finger, C2H2 type # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 1.1 0.0005 0.8 1 22 [. 375 396 .. 375 399 .. 0.90 2 ? 0.6 1.4 0.88 1.4e+03 3 22 .. 415 434 .. 414 437 .. 0.87 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0005 zf-C2H2 1 ykCpdCgksFsrksnLkrHlrt 22 y C++C+ F ++ +++ Hl++ FUN_002354-T2 375 YFCKYCKLPFQSAAQFEEHLQS 396 88*****************987 PP == domain 2 score: 0.6 bits; conditional E-value: 0.88 zf-C2H2 3 CpdCgksFsrksnLkrHlrt 22 C++C+ ++ s+ k H ++ FUN_002354-T2 415 CEYCKVHLNSESQAKEHFNS 434 *************9999876 PP >> zf-C2H2_4 C2H2-type zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.4 0.005 8 1 21 [. 375 395 .. 375 397 .. 0.92 2 ? 0.6 0.8 1.2 1.9e+03 3 20 .. 415 432 .. 413 434 .. 0.78 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.005 zf-C2H2_4 1 fkCpiCgksFsskkaLrrHlk 21 + C++C+ +F s ++ Hl+ FUN_002354-T2 375 YFCKYCKLPFQSAAQFEEHLQ 395 78*****************97 PP == domain 2 score: 0.6 bits; conditional E-value: 1.2 zf-C2H2_4 3 CpiCgksFsskkaLrrHl 20 C++C+ +s ++ + H+ FUN_002354-T2 415 CEYCKVHLNSESQAKEHF 432 ****99998888777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1008 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 943 (0.0369152); expected 510.9 (0.02) Passed bias filter: 770 (0.0301429); expected 510.9 (0.02) Passed Vit filter: 80 (0.00313173); expected 25.5 (0.001) Passed Fwd filter: 18 (0.000704639); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 16 [number of targets reported over threshold] # CPU time: 0.44u 0.40s 00:00:00.84 Elapsed: 00:00:00.43 # Mc/sec: 9464.14 // Query: FUN_002355-T1 [L=115] Description: FUN_002355 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-32 112.1 10.5 1.9e-32 111.9 10.5 1.0 1 C6_DPF CDPF1 Domain annotation for each model (and alignments): >> C6_DPF CDPF1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 111.9 10.5 7.5e-37 1.9e-32 1 93 [. 16 107 .. 16 108 .. 0.98 Alignments for each domain: == domain 1 score: 111.9 bits; conditional E-value: 7.5e-37 C6_DPF 1 feCslCeleekyeyvgkkppfaksivlleeayvlrDPFsaekkkvlvlGakCslCekavCvdeeCslfytkrfClkCakeeleefPkeiqkkl 93 f+Cs C++e++yey gkkpp +ks++lle+ayv+rDPFs+++ +l++G++C+lC+k+vC+ ++Cs+fytkrfC++C+++++ efP eiq+++ FUN_002355-T1 16 FSCSSCAFECHYEYLGKKPPCSKSVMLLEDAYVIRDPFSPSAG-HLTIGGNCCLCSKNVCMAQTCSIFYTKRFCISCVEKNIGEFPFEIQREI 107 89**************************************999.9*********************************************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (115 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 882 (0.0345273); expected 510.9 (0.02) Passed bias filter: 250 (0.00978665); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.35s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 1189.63 // Query: FUN_002356-T1 [L=1445] Description: FUN_002356 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0 1569.0 14.3 0 1568.7 14.3 1.0 1 FancD2 Fanconi anaemia protein FancD2 nuclease 0.0044 17.7 2.7 0.011 16.4 0.0 3.1 3 FANCI_S2 FANCI solenoid 2 ------ inclusion threshold ------ 5.6 7.7 12.8 9.7 6.9 1.6 2.7 2 RNA_pol_Rpc4 RNA polymerase III RPC4 8.7 4.5 12.6 0.094 11.0 4.6 1.7 2 PI3K_1B_p101 Phosphoinositide 3-kinase gamma adapter prot Domain annotation for each model (and alignments): >> FancD2 Fanconi anaemia protein FancD2 nuclease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 1568.7 14.3 0 0 2 1417 .. 2 1412 .. 1 1414 [. 0.91 Alignments for each domain: == domain 1 score: 1568.7 bits; conditional E-value: 0 FancD2 2 lrkkrrssvekkesltedasktkksksskkskksaaaeeveendsvfvkllkkaGvilkt.gekqnelavdqvvfqkklqqalrkhpsyPkvie 94 +r krr s ++ +++ +k+sk+s+ +++++aa +e ++f k++ aG+ l++ +++q+elav + vfq+++++ l+ hpsyP++i+ FUN_002356-T1 2 VRSKRRISKPSDGEPS-----AKRSKQSSSEARKNAAAGIE--ATLFSKIVEDAGLQLNNsDATQDELAVGRSVFQNRVNKLLKGHPSYPEIID 88 5555555444433332.....34444455555555666777..67*************8626899***************************** PP FancD2 95 efisglesyiededkfrncllpcvrlqdeeessavtsyqksliklllGieilqpaiiktlfeklPeflfestn..ddglnlprliinqlkwldr 186 +fi g+e ++d+++f+ llp ++e +sl ++ll ++ilqp i ++l+eklPef+ ++ + dg+n+prl++nq++w+d FUN_002356-T1 89 DFIEGFEERLQDPNRFQLSLLPVSISAEHEG---CGGSPESLTRMLLSVDILQPKIANILLEKLPEFMGDEDSnrADGINIPRLVLNQFRWMDC 179 **********************987776666...444579****************************87654116****************** PP FancD2 187 vvdgkdltaklmqlvsvaPvelqrdiitslPeiledsqhadvakelnsllventqltvPildvlsslrldpsllskvrqlvmaklsavkledlP 280 vv +k+lt+k++++v+v+ e+qrdii+ +Pe+l+ds h++va+el++ll++nt+ltv ild+ls l+l p+lls+vr+ v++ l +v+l+dlP FUN_002356-T1 180 VVQSKELTEKMLEMVGVTSLEVQRDIISCIPEVLDDSEHTEVARELSELLLQNTELTVAILDALSNLNLRPELLSEVRSSVIQMLPSVELDDLP 273 ********************************************************************************************** PP FancD2 281 vvvkfilhsvsasdaleviselrkkleleqcvlPsvlqasqsklkskgaasssaaaasssqdsvslvldviksavryektiseawlkaienide 374 vvvkfil sv + da+eviselr +l + + lP++ ++ + +++++++ s ++++ + + ld+i+s +r++k+++e w kaie+ ++ FUN_002356-T1 274 VVVKFILQSVGDNDAFEVISELRSNLSFSSTSLPPTACSTPA--EQRRSHAGSLTSKNKHG--ELFTLDAIRSGIRFQKSVAEGWTKAIESANT 363 ***********************************8654443..34444434444444444..45678************************** PP FancD2 375 vedhkvldllvllilystnanqskkgvervlrvkvrsgliqeqllqktfrtyalvlkdvfpsilalaqsllrsqdqsvvsfgsllykyafkafd 468 +hkv+dl+vllil+st+ + kk +e ++r+k+r+g + e++l+ +f+++ ++l+++f+ +l+la llrs+d+sv s++ +yk +f +fd FUN_002356-T1 364 PGNHKVVDLFVLLILHSTANR--KKVMETLIRNKIRNGHFTEEMLNAAFSSHSQILREYFSDLLSLAEILLRSPDPSVSSYACEMYKLSFISFD 455 *****************9655..6********************************************************************** PP FancD2 469 sycqqevvGalvthvcsGaeaevdvalelllelvvlkpsemalyavfvkGildyldnltpqqirklfhilsrlafskqeeqsshiqddmhlvir 562 ycqqe+vG+lvth+ sG ++e d++l++l++lv +p ma +a+f+kGildyldnlt qirklf +ls+laf+ ++++++ iqddmh+vi FUN_002356-T1 456 LYCQQEIVGTLVTHIGSGFASEADASLDVLSDLVESHPDVMAPFAIFIKGILDYLDNLTVTQIRKLFDMLSTLAFA-SRQDGGLIQDDMHIVIT 548 ****************************************************************************.9999************* PP FancD2 563 kqlsstvvkykliGiiGavtlvGsmaad.sesk........sseseeaelskeqlrqvtallelvkscsessPeaaalyydelanliqeskldp 647 kql+s +kyk+iGiiGa+++v sma++ + ++ ++++++++ls+e +qvt++l+l++ ++Peaaal+ydela +iq + +dp FUN_002356-T1 549 KQLTSNSPKYKRIGIIGAIMVVRSMAKNrIVEEgseetmgdTESERQSTLSDEAYKQVTSMLDLIRNRISQAPEAAALFYDELARIIQLGGIDP 642 **************************87533221111111134556789********************************************* PP FancD2 648 kvlewigktvledfqddfvvdlgaeiegdfpfPvkalygldeeesqdGiainllPlllkdelakdegeltaqekeqkrvsplclapffrllrlc 741 k+ wi +tv+ dfqddf++d a + ++ +P + y lde e ++ ia+nllPlll + + ++++++ ++ vs +clap+frllr+c FUN_002356-T1 643 KIESWISDTVVGDFQDDFLIDREAPV-ASESVPLELCYALDESE-EGSIAVNLLPLLLAARNS----STNKNKTDRSAVSLICLAPHFRLLRVC 730 *********************87655.55578********9976.699*********954443....45577778889**************** PP FancD2 742 vekqhdGdleeidglldcPliltdlevvekleslskkereflcsllfltinwfrevvnafckqkdpemklkvltrlknivelqtllekalavtP 835 +e q +Gdle id+ll+cPl+ ++ + +e+l +++re++c lf+t+nwfrevvnaf q+dpem++k ++rl++i+el ++lek lavtP FUN_002356-T1 731 EESQRKGDLEGIDALLGCPLVSVKQDILKEIETLDQADREIICGALFFTVNWFREVVNAFAPQRDPEMRGKSISRLQTITELHEILEKFLAVTP 824 ********************************************************************************************** PP FancD2 836 dyvPplanfdletldvlpksssavaakkkkke....kagkkrkadaskassedksqkeeaseaeesqseksqaekekekkeekasvslqsyraf 925 ++ Ppla+fd e + v + s v+ +k+kk+ ++g +kad+s + ++k +++++ +a +q + + kek+k + + vs++ yraf FUN_002356-T1 825 SFKPPLASFDFEDSLVANAVSR-VNGSKTKKGkkakSGGDGEKADDSIEKEAEKENANDKEDA--TQIDTAKNTKEKDK-TTPPLVSMTHYRAF 914 ***********98755444333.4444444331112344555665555555554444444444..44455566666666.66889********* PP FancD2 926 freldievlsvlqcGllskslldtelhtkvreevqlGPaellflledlsrklefsltaaaakripflkskadknvGfshlqqrsakeiascvvq 1019 +reld++++ +l+c l+s+++ld+e+ t+ + ++l ++l flledlsrkle+sl a+a+ r +flk + dk vGfs l + s+ke+a++vv+ FUN_002356-T1 915 LRELDLKAFGILECELVSRAVLDSEMNTEETTILRLQAPQLEFLLEDLSRKLEHSLSASASSRRTFLKVRHDKLVGFSNLSRYSSKEVATFVVD 1008 ********************************************************************************************** PP FancD2 1020 lltalcnhlenihnyfqallaenegvvdaaavdvqekqlmssayqrllqvlhtlfawsGfsqpekrkllksalevlagrlkekeadlt.leelv 1112 ll++l +hle + +fq l+a+n+g d+++ + e +m+s++++l+ l+ lfawsGf +++ llk+al vl++r+k + ++++ l+el+ FUN_002356-T1 1009 LLPSLFEHLEATSAFFQGLMAQNDGLLDGPGYNTTEASTMASCFRLLFSCLQYLFAWSGFLMSQHQALLKKALFVLSSRIKLSSKSQPgLQELL 1102 *********************************************************************************98887755***** PP FancD2 1113 kqsfeylqnfrssvPslqtalylirllivlleksa.aaaakkeklaslarqflcqewvtasGekekgnkfndqlhtllsiylehtddvlkaiee 1205 kqsf+yl f svP+++ta++l++ll+vl e+ ++++ la l+ +fl +ew++++Geke g+kfn++l+ ll +l ++d l +iee FUN_002356-T1 1103 KQSFHYLEQFCASVPNINTAVSLTKLLVVLCERQRdDNSNMNTSLADLTGKFLKREWIRSDGEKETGAKFNESLQFLLRFHLSCAADTLATIEE 1196 ********************************999566777889************************************************** PP FancD2 1206 iageGvpelln.sskdassssfPtltrqtflvfyrvllaelekavrkiq..agkaadssevqeeklltwnlavrdfsilinlvkvfds.rpvln 1295 iag ++ l++ kda+s+++Ptltr ++ fyr+++ el v++ + + +++d e ++e+l+ n+avr f+i+inlvk f+ r +l FUN_002356-T1 1197 IAGGAMTSLVEdDEKDACSEAYPTLTRSSLACFYRAMMEELVSNVKQTHsvPLRSSDPLESHKERLVKLNIAVRIFHIMINLVKAFNQrRGILG 1290 **********7257********************************9873356899******************************972579** PP FancD2 1296 vclkyGrlfveaflklgmPlldfsfkkhkedvlsllktfqlstrqlhhlcGhskirqdtsltnhvPllkkslellvyrvkamlvlnncqeafwl 1389 + lkyGrlfve flklgmP ldf f+ hk+d+ +llk +q str l h+cGhsk+ +d sltnhvP++kk le +v+rvkaml+ln+c+eafwl FUN_002356-T1 1291 ASLKYGRLFVEIFLKLGMPTLDFMFRTHKDDIHGLLKNLQQSTRSLQHFCGHSKVTKDLSLTNHVPAVKKCLETFVFRVKAMLALNKCHEAFWL 1384 ********************************************************************************************** PP FancD2 1390 GnlknrdlkGeeilsqrsqesdeeeeed 1417 Gnlknrd++Ge i sq+s+ +++++e+d FUN_002356-T1 1385 GNLKNRDIHGEVISSQQSNTTEDDKEQD 1412 ******************9999988887 PP >> FANCI_S2 FANCI solenoid 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 1.1 7.3e+03 54 81 .. 220 246 .. 179 278 .. 0.58 2 ! 16.4 0.0 1.7e-06 0.011 51 154 .. 458 565 .. 438 567 .. 0.90 3 ? -2.3 0.1 0.97 6.2e+03 75 104 .. 1056 1085 .. 1049 1105 .. 0.80 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.1 FANCI_S2 54 eIleqlvnrivsksesvsqkyielLskl 81 e+ ++l + +++++e + + +++ Ls+l FUN_002356-T1 220 EVARELSELLLQNTELTVA-ILDALSNL 246 3444444444444444443.45555554 PP == domain 2 score: 16.4 bits; conditional E-value: 1.7e-06 FANCI_S2 51 irseIleqlvnrivsksesvsqkyielLsklvkklpllllehssklkelLdylsflplstaqrllkAllpLikvses....lrdslilvLRKalfs 142 ++eI+ +lv i s s ++ +++Ls+lv+++p ++ + +k +Ldyl l ++ ++l++ l+ L +s++ ++d + +v+ K l s FUN_002356-T1 458 CQQEIVGTLVTHIGSGFASEADASLDVLSDLVESHPDVMAPFAIFIKGILDYLDNLTVTQIRKLFDMLSTLAFASRQdgglIQDDMHIVITKQLTS 553 5799************9999999************************************************99987666669************99 PP FANCI_S2 143 releaRkaAvtG 154 + + ++++ G FUN_002356-T1 554 NSPKYKRIGIIG 565 988877777665 PP == domain 3 score: -2.3 bits; conditional E-value: 0.97 FANCI_S2 75 ielLsklvkklpllllehssklkelLdyls 104 + +L++l +l+++h++ lk+ L ls FUN_002356-T1 1056 FSCLQYLFAWSGFLMSQHQALLKKALFVLS 1085 568888888888899999888888886665 PP >> RNA_pol_Rpc4 RNA polymerase III RPC4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 3.8 0.0059 38 13 69 .. 823 901 .. 818 908 .. 0.55 2 ? 6.9 1.6 0.0015 9.7 28 67 .. 1401 1440 .. 1355 1444 .. 0.60 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0059 RNA_pol_Rpc4 13 lPelk......................eekeeskekeeeeeeekeeeekekeekeekeekkkkkkeekkkkkskekast 69 +P++k +++++ k++++ + ek++++ eke+++e++++k+++++ +++k++kek++t FUN_002356-T1 823 TPSFKpplasfdfedslvanavsrvngSKTKKGKKAKSGGDGEKADDSIEKEAEKENANDKEDATQIDTAKNTKEKDKT 901 5666666667778888888877777764444444444444555555555554444444455555555555555554444 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0015 RNA_pol_Rpc4 28 eeeeeekeeeekekeekeekeekkkkkkeekkkkkskeka 67 +++++e+++e++e++e++e+++++++++ee+++k+++e++ FUN_002356-T1 1401 QSNTTEDDKEQDEEAEEMEDDDDEEDETEENESKNGDEQS 1440 2222222223333333333333333334444444444444 PP >> PI3K_1B_p101 Phosphoinositide 3-kinase gamma adapter protein p101 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 1.0 0.3 1.9e+03 327 354 .. 867 894 .. 831 918 .. 0.42 2 ? 11.0 4.6 1.5e-05 0.094 277 341 .. 1371 1438 .. 1337 1445 .] 0.67 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 0.3 PI3K_1B_p101 327 eedleeedeeaeedsealrastlstvss 354 +d e++ e+e+++++ a+++ t+ + FUN_002356-T1 867 ADDSIEKEAEKENANDKEDATQIDTAKN 894 2222222222222222222223333222 PP == domain 2 score: 11.0 bits; conditional E-value: 1.5e-05 PI3K_1B_p101 277 lplpvakcytlsW..ekdnfDvLneilekeaelaeaeeseeeeeedeee.kdeeedleeedeeaeeds 341 +l+ kc+ W + n D+ e++++++++++ +++e++ee++e e +d+eed +ee+e+++ d+ FUN_002356-T1 1371 AMLALNKCHEAFWlgNLKNRDIHGEVISSQQSNTTEDDKEQDEEAEEMEdDDDEEDETEENESKNGDE 1438 468999*******66678***********999998888887777776651444445555555444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1445 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1460 (0.057154); expected 510.9 (0.02) Passed bias filter: 745 (0.0291642); expected 510.9 (0.02) Passed Vit filter: 114 (0.00446271); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.62u 0.43s 00:00:01.05 Elapsed: 00:00:00.44 # Mc/sec: 13335.97 // Query: FUN_002356-T2 [L=1435] Description: FUN_002356 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0 1564.8 15.4 0 1564.4 15.4 1.0 1 FancD2 Fanconi anaemia protein FancD2 nuclease 0.0043 17.7 2.7 0.011 16.4 0.0 3.1 3 FANCI_S2 FANCI solenoid 2 ------ inclusion threshold ------ 6.9 7.4 12.8 9.7 6.9 1.6 2.5 2 RNA_pol_Rpc4 RNA polymerase III RPC4 7.2 4.7 12.6 0.093 11.0 4.6 1.8 2 PI3K_1B_p101 Phosphoinositide 3-kinase gamma adapter prot Domain annotation for each model (and alignments): >> FancD2 Fanconi anaemia protein FancD2 nuclease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 1564.4 15.4 0 0 23 1417 .. 8 1402 .. 4 1404 .. 0.92 Alignments for each domain: == domain 1 score: 1564.4 bits; conditional E-value: 0 FancD2 23 tkksksskkskksaaaeeveendsvfvkllkkaGvilkt.gekqnelavdqvvfqkklqqalrkhpsyPkvieefisglesyiededkfrncll 115 +k+sk+s+ +++++aa +e ++f k++ aG+ l++ +++q+elav + vfq+++++ l+ hpsyP++i++fi g+e ++d+++f+ ll FUN_002356-T2 8 AKRSKQSSSEARKNAAAGIE--ATLFSKIVEDAGLQLNNsDATQDELAVGRSVFQNRVNKLLKGHPSYPEIIDDFIEGFEERLQDPNRFQLSLL 99 45666666666667777787..68*************8626899************************************************** PP FancD2 116 pcvrlqdeeessavtsyqksliklllGieilqpaiiktlfeklPeflfestn..ddglnlprliinqlkwldrvvdgkdltaklmqlvsvaPve 207 p ++e +sl ++ll ++ilqp i ++l+eklPef+ ++ + dg+n+prl++nq++w+d vv +k+lt+k++++v+v+ e FUN_002356-T2 100 PVSISAEHEG---CGGSPESLTRMLLSVDILQPKIANILLEKLPEFMGDEDSnrADGINIPRLVLNQFRWMDCVVQSKELTEKMLEMVGVTSLE 190 *987776666...444579****************************87654116*************************************** PP FancD2 208 lqrdiitslPeiledsqhadvakelnsllventqltvPildvlsslrldpsllskvrqlvmaklsavkledlPvvvkfilhsvsasdalevise 301 +qrdii+ +Pe+l+ds h++va+el++ll++nt+ltv ild+ls l+l p+lls+vr+ v++ l +v+l+dlPvvvkfil sv + da+evise FUN_002356-T2 191 VQRDIISCIPEVLDDSEHTEVARELSELLLQNTELTVAILDALSNLNLRPELLSEVRSSVIQMLPSVELDDLPVVVKFILQSVGDNDAFEVISE 284 ********************************************************************************************** PP FancD2 302 lrkkleleqcvlPsvlqasqsklkskgaasssaaaasssqdsvslvldviksavryektiseawlkaienidevedhkvldllvllilystnan 395 lr +l + + lP++ ++ + +++++++ s ++++ + + ld+i+s +r++k+++e w kaie+ ++ +hkv+dl+vllil+st+ + FUN_002356-T2 285 LRSNLSFSSTSLPPTACSTPA--EQRRSHAGSLTSKNKHG--ELFTLDAIRSGIRFQKSVAEGWTKAIESANTPGNHKVVDLFVLLILHSTANR 374 **************8654443..34444434444444444..45678*******************************************9655 PP FancD2 396 qskkgvervlrvkvrsgliqeqllqktfrtyalvlkdvfpsilalaqsllrsqdqsvvsfgsllykyafkafdsycqqevvGalvthvcsGaea 489 kk +e ++r+k+r+g + e++l+ +f+++ ++l+++f+ +l+la llrs+d+sv s++ +yk +f +fd ycqqe+vG+lvth+ sG ++ FUN_002356-T2 375 --KKVMETLIRNKIRNGHFTEEMLNAAFSSHSQILREYFSDLLSLAEILLRSPDPSVSSYACEMYKLSFISFDLYCQQEIVGTLVTHIGSGFAS 466 ..6******************************************************************************************* PP FancD2 490 evdvalelllelvvlkpsemalyavfvkGildyldnltpqqirklfhilsrlafskqeeqsshiqddmhlvirkqlsstvvkykliGiiGavtl 583 e d++l++l++lv +p ma +a+f+kGildyldnlt qirklf +ls+laf+ ++++++ iqddmh+vi kql+s +kyk+iGiiGa+++ FUN_002356-T2 467 EADASLDVLSDLVESHPDVMAPFAIFIKGILDYLDNLTVTQIRKLFDMLSTLAFA-SRQDGGLIQDDMHIVITKQLTSNSPKYKRIGIIGAIMV 559 *******************************************************.9999********************************** PP FancD2 584 vGsmaad.sesk........sseseeaelskeqlrqvtallelvkscsessPeaaalyydelanliqeskldpkvlewigktvledfqddfvvd 668 v sma++ + ++ ++++++++ls+e +qvt++l+l++ ++Peaaal+ydela +iq + +dpk+ wi +tv+ dfqddf++d FUN_002356-T2 560 VRSMAKNrIVEEgseetmgdTESERQSTLSDEAYKQVTSMLDLIRNRISQAPEAAALFYDELARIIQLGGIDPKIESWISDTVVGDFQDDFLID 653 *****87533221111111134556789****************************************************************** PP FancD2 669 lgaeiegdfpfPvkalygldeeesqdGiainllPlllkdelakdegeltaqekeqkrvsplclapffrllrlcvekqhdGdleeidglldcPli 762 a + ++ +P + y lde e ++ ia+nllPlll + + ++++++ ++ vs +clap+frllr+c+e q +Gdle id+ll+cPl+ FUN_002356-T2 654 REAPV-ASESVPLELCYALDESE-EGSIAVNLLPLLLAARNS----STNKNKTDRSAVSLICLAPHFRLLRVCEESQRKGDLEGIDALLGCPLV 741 87655.55578********9976.699*********954443....45577778889************************************* PP FancD2 763 ltdlevvekleslskkereflcsllfltinwfrevvnafckqkdpemklkvltrlknivelqtllekalavtPdyvPplanfdletldvlpkss 856 ++ + +e+l +++re++c lf+t+nwfrevvnaf q+dpem++k ++rl++i+el ++lek lavtP++ Ppla+fd e + v + s FUN_002356-T2 742 SVKQDILKEIETLDQADREIICGALFFTVNWFREVVNAFAPQRDPEMRGKSISRLQTITELHEILEKFLAVTPSFKPPLASFDFEDSLVANAVS 835 ************************************************************************************9875544433 PP FancD2 857 savaakkkkke....kagkkrkadaskassedksqkeeaseaeesqseksqaekekekkeekasvslqsyraffreldievlsvlqcGllsksl 946 v+ +k+kk+ ++g +kad+s + ++k +++++ +a +q + + kek+k + + vs++ yraf+reld++++ +l+c l+s+++ FUN_002356-T2 836 R-VNGSKTKKGkkakSGGDGEKADDSIEKEAEKENANDKEDA--TQIDTAKNTKEKDK-TTPPLVSMTHYRAFLRELDLKAFGILECELVSRAV 925 3.4444444331112344555665555555554444444444..44455566666666.66889****************************** PP FancD2 947 ldtelhtkvreevqlGPaellflledlsrklefsltaaaakripflkskadknvGfshlqqrsakeiascvvqlltalcnhlenihnyfqalla 1040 ld+e+ t+ + ++l ++l flledlsrkle+sl a+a+ r +flk + dk vGfs l + s+ke+a++vv+ll++l +hle + +fq l+a FUN_002356-T2 926 LDSEMNTEETTILRLQAPQLEFLLEDLSRKLEHSLSASASSRRTFLKVRHDKLVGFSNLSRYSSKEVATFVVDLLPSLFEHLEATSAFFQGLMA 1019 ********************************************************************************************** PP FancD2 1041 enegvvdaaavdvqekqlmssayqrllqvlhtlfawsGfsqpekrkllksalevlagrlkekeadlt.leelvkqsfeylqnfrssvPslqtal 1133 +n+g d+++ + e +m+s++++l+ l+ lfawsGf +++ llk+al vl++r+k + ++++ l+el+kqsf+yl f svP+++ta+ FUN_002356-T2 1020 QNDGLLDGPGYNTTEASTMASCFRLLFSCLQYLFAWSGFLMSQHQALLKKALFVLSSRIKLSSKSQPgLQELLKQSFHYLEQFCASVPNINTAV 1113 ************************************************************98887755************************** PP FancD2 1134 ylirllivlleksa.aaaakkeklaslarqflcqewvtasGekekgnkfndqlhtllsiylehtddvlkaieeiageGvpelln.sskdassss 1225 +l++ll+vl e+ ++++ la l+ +fl +ew++++Geke g+kfn++l+ ll +l ++d l +ieeiag ++ l++ kda+s++ FUN_002356-T2 1114 SLTKLLVVLCERQRdDNSNMNTSLADLTGKFLKREWIRSDGEKETGAKFNESLQFLLRFHLSCAADTLATIEEIAGGAMTSLVEdDEKDACSEA 1207 ***********999566777889************************************************************7257******* PP FancD2 1226 fPtltrqtflvfyrvllaelekavrkiq..agkaadssevqeeklltwnlavrdfsilinlvkvfds.rpvlnvclkyGrlfveaflklgmPll 1316 +Ptltr ++ fyr+++ el v++ + + +++d e ++e+l+ n+avr f+i+inlvk f+ r +l + lkyGrlfve flklgmP l FUN_002356-T2 1208 YPTLTRSSLACFYRAMMEELVSNVKQTHsvPLRSSDPLESHKERLVKLNIAVRIFHIMINLVKAFNQrRGILGASLKYGRLFVEIFLKLGMPTL 1301 *************************9873356899******************************972579*********************** PP FancD2 1317 dfsfkkhkedvlsllktfqlstrqlhhlcGhskirqdtsltnhvPllkkslellvyrvkamlvlnncqeafwlGnlknrdlkGeeilsqrsqes 1410 df f+ hk+d+ +llk +q str l h+cGhsk+ +d sltnhvP++kk le +v+rvkaml+ln+c+eafwlGnlknrd++Ge i sq+s+ + FUN_002356-T2 1302 DFMFRTHKDDIHGLLKNLQQSTRSLQHFCGHSKVTKDLSLTNHVPAVKKCLETFVFRVKAMLALNKCHEAFWLGNLKNRDIHGEVISSQQSNTT 1395 *******************************************************************************************999 PP FancD2 1411 deeeeed 1417 ++++e+d FUN_002356-T2 1396 EDDKEQD 1402 9988887 PP >> FANCI_S2 FANCI solenoid 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 0.1 1.1 7.2e+03 54 81 .. 210 236 .. 169 268 .. 0.58 2 ! 16.4 0.0 1.7e-06 0.011 51 154 .. 448 555 .. 428 557 .. 0.90 3 ? -2.3 0.1 0.96 6.1e+03 75 104 .. 1046 1075 .. 1039 1095 .. 0.80 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 1.1 FANCI_S2 54 eIleqlvnrivsksesvsqkyielLskl 81 e+ ++l + +++++e + + +++ Ls+l FUN_002356-T2 210 EVARELSELLLQNTELTVA-ILDALSNL 236 3444444444444444443.45555554 PP == domain 2 score: 16.4 bits; conditional E-value: 1.7e-06 FANCI_S2 51 irseIleqlvnrivsksesvsqkyielLsklvkklpllllehssklkelLdylsflplstaqrllkAllpLikvses....lrdslilvLRKalfs 142 ++eI+ +lv i s s ++ +++Ls+lv+++p ++ + +k +Ldyl l ++ ++l++ l+ L +s++ ++d + +v+ K l s FUN_002356-T2 448 CQQEIVGTLVTHIGSGFASEADASLDVLSDLVESHPDVMAPFAIFIKGILDYLDNLTVTQIRKLFDMLSTLAFASRQdgglIQDDMHIVITKQLTS 543 5799************9999999************************************************99987666669************99 PP FANCI_S2 143 releaRkaAvtG 154 + + ++++ G FUN_002356-T2 544 NSPKYKRIGIIG 555 988877777665 PP == domain 3 score: -2.3 bits; conditional E-value: 0.96 FANCI_S2 75 ielLsklvkklpllllehssklkelLdyls 104 + +L++l +l+++h++ lk+ L ls FUN_002356-T2 1046 FSCLQYLFAWSGFLMSQHQALLKKALFVLS 1075 568888888888899999888888886665 PP >> RNA_pol_Rpc4 RNA polymerase III RPC4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 3.8 0.0059 38 13 69 .. 813 891 .. 808 898 .. 0.55 2 ? 6.9 1.6 0.0015 9.7 28 67 .. 1391 1430 .. 1345 1434 .. 0.60 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.0059 RNA_pol_Rpc4 13 lPelk......................eekeeskekeeeeeeekeeeekekeekeekeekkkkkkeekkkkkskekast 69 +P++k +++++ k++++ + ek++++ eke+++e++++k+++++ +++k++kek++t FUN_002356-T2 813 TPSFKpplasfdfedslvanavsrvngSKTKKGKKAKSGGDGEKADDSIEKEAEKENANDKEDATQIDTAKNTKEKDKT 891 5666666667778888888877777764444444444444555555555554444444455555555555555554444 PP == domain 2 score: 6.9 bits; conditional E-value: 0.0015 RNA_pol_Rpc4 28 eeeeeekeeeekekeekeekeekkkkkkeekkkkkskeka 67 +++++e+++e++e++e++e+++++++++ee+++k+++e++ FUN_002356-T2 1391 QSNTTEDDKEQDEEAEEMEDDDDEEDETEENESKNGDEQS 1430 2222222223333333333333333334444444444444 PP >> PI3K_1B_p101 Phosphoinositide 3-kinase gamma adapter protein p101 subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 1.0 0.29 1.9e+03 327 354 .. 857 884 .. 821 908 .. 0.42 2 ? 11.0 4.6 1.5e-05 0.093 277 341 .. 1361 1428 .. 1327 1435 .] 0.67 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 0.29 PI3K_1B_p101 327 eedleeedeeaeedsealrastlstvss 354 +d e++ e+e+++++ a+++ t+ + FUN_002356-T2 857 ADDSIEKEAEKENANDKEDATQIDTAKN 884 2222222222222222222223333222 PP == domain 2 score: 11.0 bits; conditional E-value: 1.5e-05 PI3K_1B_p101 277 lplpvakcytlsW..ekdnfDvLneilekeaelaeaeeseeeeeedeee.kdeeedleeedeeaeeds 341 +l+ kc+ W + n D+ e++++++++++ +++e++ee++e e +d+eed +ee+e+++ d+ FUN_002356-T2 1361 AMLALNKCHEAFWlgNLKNRDIHGEVISSQQSNTTEDDKEQDEEAEEMEdDDDEEDETEENESKNGDE 1428 468999*******66678***********999998888887777776651444445555555444443 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1435 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1449 (0.0567234); expected 510.9 (0.02) Passed bias filter: 739 (0.0289293); expected 510.9 (0.02) Passed Vit filter: 114 (0.00446271); expected 25.5 (0.001) Passed Fwd filter: 36 (0.00140928); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.60u 0.44s 00:00:01.04 Elapsed: 00:00:00.43 # Mc/sec: 13378.46 // Query: FUN_002357-T1 [L=663] Description: FUN_002357 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-08 35.6 24.5 1.5e-08 35.6 24.5 4.5 4 DUF4594 Domain of unknown function (DUF4594) ------ inclusion threshold ------ 0.012 16.1 5.2 0.11 13.0 0.1 2.8 2 DUF2509 Protein of unknown function (DUF2509) Domain annotation for each model (and alignments): >> DUF4594 Domain of unknown function (DUF4594) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 6.5 0.88 1.1e+04 115 173 .. 103 158 .. 64 162 .. 0.62 2 ! 35.6 24.5 1.2e-12 1.5e-08 6 102 .. 158 254 .. 155 306 .. 0.67 3 ? 1.9 1.5 0.026 3.3e+02 6 60 .. 308 363 .. 302 379 .. 0.75 4 ? -1.6 0.2 0.3 3.9e+03 101 156 .. 518 569 .. 508 597 .. 0.52 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.88 DUF4594 115 srkgprsqrklqppklptdgkflsrggqqsrpsvasatrskargkerltgrarrwetke 173 ++ + r q +q +k +++ k +++ ++ ++++g r+tg a r+ +++ FUN_002357-T1 103 GWGKGRGQMLQQMRKQTMKAKEWE--AKRKENVKKEEEAQRKQGA-RATGSASRFLADD 158 444556666677777777777222..2222222223334556665.7888888876555 PP == domain 2 score: 35.6 bits; conditional E-value: 1.2e-12 DUF4594 6 rdraegsrrggrn...rsgpdqeavssdseqkgareprspglvgaaptlsltgeerwdYlrWKqEReqiDlaRLaRHrdaqGdWrRpWDldkakpm 98 dr + sr +grn ++g ++++v s +++++ rs g + + ++ l g+er++Y +WK ER +iD +R aR ++a G+W+R+WD k + FUN_002357-T1 158 DDRVDMSRARGRNehsWGGGNFNNVVSRVQREKEAS-RS-GRFRGNSEMNLSGKERQEYKKWKEERSRIDEERKARQKKA-GNWSRAWDQPKMWDT 250 56666666555433339*******999999885533.45.5553455699**************************9998.********8886554 PP DUF4594 99 lkds 102 k FUN_002357-T1 251 RKKM 254 4433 PP == domain 3 score: 1.9 bits; conditional E-value: 0.026 DUF4594 6 rdraegsrrggrnrsgpdqeavssdseqkgareprspglvgaap.tlsltgeerwd 60 ++ +eg + ++ ++ ++++++ sds+ + + s ++ +++ +++l g+e d FUN_002357-T1 308 SQHKEGGKVTEEDWGDSTENNIGSDSKDELKESGVSEMEKKQVEnSRALDGKEDDD 363 68899*********************999655555555553444377777766555 PP == domain 4 score: -1.6 bits; conditional E-value: 0.3 DUF4594 101 dsskpreegparag.srkgprsqrklqppklptdgkflsrggqqsrpsvasatrska 156 d++k ++ + r++ + +++ + + ++++g+ + +g ++ v+++ s+ FUN_002357-T1 518 DEPK--SNISRRQDmNTGNNKCESQPDNELISPEGENAK-TGFSAEKVVSEQ--SHS 569 4433..333333442222334445555556666666333.333333333222..333 PP >> DUF2509 Protein of unknown function (DUF2509) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 8.4e-06 0.11 60 118 .. 46 104 .. 31 106 .. 0.91 2 ? 2.8 2.2 0.012 1.5e+02 8 57 .. 204 256 .. 201 266 .. 0.77 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 8.4e-06 DUF2509 60 qqqeeelkaClrrlsedealllkgeealaaekqnlslyqlvkvkessdedelvflpsGW 118 +++ee ++a +r+ +++++ ll+ ++++ ++ +n ly ++vk++ ++ ++ +++GW FUN_002357-T1 46 AKKEEMVEAKMRMIKKKNEELLRRQKEIEEDRKNADLYSEMAVKRNPGNFHIDSSNQGW 104 56677888999************************************************ PP == domain 2 score: 2.8 bits; conditional E-value: 0.012 DUF2509 8 llLqglhrqldnaaq...rvaderrylraqaqaesaLeWGkaqsWstkaeewq 57 + L+g +rq+ ++++ de+r r+++ ++ + +W + ++W t+++ w FUN_002357-T1 204 MNLSGKERQEYKKWKeerSRIDEERKARQKKAGNWSRAWDQPKMWDTRKKMWM 256 67888888877766511145789999999999999************988886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (663 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2963 (0.115991); expected 510.9 (0.02) Passed bias filter: 534 (0.0209043); expected 510.9 (0.02) Passed Vit filter: 54 (0.00211392); expected 25.5 (0.001) Passed Fwd filter: 15 (0.000587199); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.43u 0.41s 00:00:00.84 Elapsed: 00:00:00.42 # Mc/sec: 6372.06 // Query: FUN_002358-T1 [L=144] Description: FUN_002358 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.5e-19 67.9 0.0 2.7e-18 66.4 0.0 1.7 2 Glutaredoxin Glutaredoxin 1.7e-05 25.5 0.0 3.4e-05 24.6 0.0 1.4 1 GST_N_3 Glutathione S-transferase, N-terminal domain 0.00082 19.7 0.7 0.77 10.0 0.1 2.2 2 DSBA DSBA-like thioredoxin domain 0.00096 20.2 0.0 0.0015 19.5 0.0 1.3 1 GST_N_2 Glutathione S-transferase, N-terminal domain 0.0015 19.3 0.0 0.0026 18.6 0.0 1.5 1 Glrx-like Glutaredoxin-like domain (DUF836) ------ inclusion threshold ------ 0.025 15.2 0.1 0.88 10.2 0.2 2.1 2 Thioredoxin_4 Thioredoxin 0.092 13.6 0.1 0.15 12.9 0.1 1.5 1 Thioredoxin_2 Thioredoxin-like domain 0.17 12.3 0.2 1.8 9.0 0.0 2.3 2 WHD_plant_repro Winged helix-turn-helix domain in plant repr Domain annotation for each model (and alignments): >> Glutaredoxin Glutaredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 1.6 5.1e+03 35 45 .. 12 22 .. 9 40 .. 0.66 2 ! 66.4 0.0 8.5e-22 2.7e-18 1 60 [] 56 119 .. 56 119 .. 0.97 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.6 Glutaredoxin 35 peireelkels 45 ++reel +++ FUN_002358-T1 12 RDLREELHSVA 22 57889998877 PP == domain 2 score: 66.4 bits; conditional E-value: 8.5e-22 Glutaredoxin 1 vvlftkptCpfCkkakrlLkelgvd.feevdvdedp...eireelkelsgwrtvPqvfidgehi 60 vv+++k++CpfCkkak++L e g++ ++ +++d ++ +++++lke++g r+vP+vfi+g+++ FUN_002358-T1 56 VVVYSKTYCPFCKKAKSALGETGLKdYVLFELDTMDdgdAYQDALKEITGARSVPRVFIGGKFV 119 8**********************777*******999999***********************97 PP >> GST_N_3 Glutathione S-transferase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.0 1.1e-08 3.4e-05 2 58 .. 59 120 .. 58 125 .. 0.83 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 1.1e-08 GST_N_3 2 ygfpgSpyarkvriaLnekglp....yevvpvppgdk.rpellakspagkvPvLeddgevlt 58 y+ ++p+++k++ aL e+gl+ +e+ ++ gd ++l+++++a+ vP ++g+ ++ FUN_002358-T1 59 YSKTYCPFCKKAKSALGETGLKdyvlFELDTMDDGDAyQDALKEITGARSVPRVFIGGKFVG 120 78899****************77666666666666656**************9988888776 PP >> DSBA DSBA-like thioredoxin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 10.0 0.1 0.00024 0.77 2 21 .. 56 75 .. 55 87 .. 0.90 2 ! 8.4 0.1 0.00075 2.4 157 188 .. 99 130 .. 86 132 .. 0.84 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00024 DSBA 2 vdeffDflCPyCylakerle 21 v++++ +CP+C+ ak+ l FUN_002358-T1 56 VVVYSKTYCPFCKKAKSALG 75 899************99886 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00075 DSBA 157 aaaislgvtGvPtvvvggkmvfGadrldtlae 188 a+ + g++ vP v++ggk+v G d++++l++ FUN_002358-T1 99 ALKEITGARSVPRVFIGGKFVGGGDDVKALHS 130 5555567788*****************99987 PP >> GST_N_2 Glutathione S-transferase, N-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 4.8e-07 0.0015 1 57 [. 63 119 .. 63 127 .. 0.83 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 4.8e-07 GST_N_2 1 fspfaqrvrlaLeekglp.yeielvplapdpkdkppellalnplgtvPvLvdpdgtvl 57 ++pf+ ++ aL e gl+ y + +++ d++ ++l+++++++ vP +++ +g+ + FUN_002358-T1 63 YCPFCKKAKSALGETGLKdYVLFELDTMDDGDAYQDALKEITGARSVPRVFI-GGKFV 119 7****************625555566668999999*************9999.66655 PP >> Glrx-like Glutaredoxin-like domain (DUF836) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.0 8.1e-07 0.0026 1 35 [. 55 91 .. 55 118 .. 0.85 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 8.1e-07 Glrx-like 1 kliLyskpgCglCeeaeevLeelaledg..lelevid 35 k++ ysk +C+ C++a+ +L e l+d +el + d FUN_002358-T1 55 KVVVYSKTYCPFCKKAKSALGETGLKDYvlFELDTMD 91 699******************9777776556666655 PP >> Thioredoxin_4 Thioredoxin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.2 0.00027 0.88 14 42 .. 53 82 .. 50 99 .. 0.86 2 ? 3.2 0.0 0.039 1.2e+02 135 159 .. 104 128 .. 84 131 .. 0.76 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00027 Thioredoxin_4 14 pvtvveyeslrCPhCaefeeevl.klleky 42 +++vv+y+ CP C +++ ++ l++y FUN_002358-T1 53 ENKVVVYSKTYCPFCKKAKSALGeTGLKDY 82 579***************999985556666 PP == domain 2 score: 3.2 bits; conditional E-value: 0.039 Thioredoxin_4 135 agiestPtiiingkkvdepltpeel 159 g s+P ++i+gk v + ++++l FUN_002358-T1 104 TGARSVPRVFIGGKFVGGGDDVKAL 128 47889**********9877776665 PP >> Thioredoxin_2 Thioredoxin-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.1 4.6e-05 0.15 7 37 .. 54 92 .. 49 138 .. 0.67 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 4.6e-05 Thioredoxin_2 7 pvlvvftdpdCpyCkklkkelkelddvtky.........l 37 +vv++++ Cp+Ckk k l e ++++y FUN_002358-T1 54 NKVVVYSKTYCPFCKKAKSALGET-GLKDYvlfeldtmdD 92 679*************99887777.666664334443332 PP >> WHD_plant_repro Winged helix-turn-helix domain in plant reproductive proteins # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.1 0.2 6.5e+02 24 35 .. 7 18 .. 2 23 .. 0.81 2 ? 9.0 0.0 0.00055 1.8 34 53 .. 69 88 .. 44 96 .. 0.90 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.2 WHD_plant_repro 24 kaisrqelRdaa 35 + ++r++lR++ FUN_002358-T1 7 SRMMRRDLREEL 18 6899*****986 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00055 WHD_plant_repro 34 aarkhIGDtGLlDfvLKsln 53 +a++ G+tGL D+vL l+ FUN_002358-T1 69 KAKSALGETGLKDYVLFELD 88 79999***********7776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (144 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 844 (0.0330397); expected 510.9 (0.02) Passed bias filter: 727 (0.0284596); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1448.13 // Query: FUN_002359-T1 [L=195] Description: FUN_002359 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-31 107.8 0.8 6.9e-31 107.2 0.8 1.2 1 RD3 RD3 protein Domain annotation for each model (and alignments): >> RD3 RD3 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 107.2 0.8 2.7e-35 6.9e-31 16 124 .. 21 130 .. 10 135 .. 0.91 Alignments for each domain: == domain 1 score: 107.2 bits; conditional E-value: 2.7e-35 RD3 16 pgeevvtetlllElewqvkererqqrekeeeerkaktgvDYswlvsyprkrkqisaserlqLedlCakikPsetgkvisrfrevlaenevevkelv 111 + vv+e l+ El q+k + r +re e+e++k+ +++DYswl+s+p k++qi+ erl+Le+l++k++P+++g+vis fr++++ + +v+el+ FUN_002359-T1 21 AERDVVCEALMEELDSQIKDVARINREVEREKKKMANQADYSWLISTPPKSYQIPHMERLTLEQLASKVRPEDSGNVISEFRDIVEGIPRDVEELP 116 3478999***************************************************************************************** PP RD3 112 elfksvlk.eflee 124 ++++ v++ ++le+ FUN_002359-T1 117 KIMRFVIEkNYLER 130 ******96256655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (195 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1204 (0.0471325); expected 510.9 (0.02) Passed bias filter: 933 (0.0365238); expected 510.9 (0.02) Passed Vit filter: 65 (0.00254453); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.38s 00:00:00.66 Elapsed: 00:00:00.40 # Mc/sec: 1955.81 // Query: FUN_002360-T1 [L=606] Description: FUN_002360 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.029 14.0 1.5 0.069 12.7 1.5 1.6 1 DUF6175 Family of unknown function (DUF6175) 0.035 14.5 0.8 0.068 13.6 0.8 1.4 1 CC_STIL STIL coiled coil region 0.53 10.0 2.5 1.3 8.7 2.5 1.6 1 DUF4407 Domain of unknown function (DUF4407) Domain annotation for each model (and alignments): >> DUF6175 Family of unknown function (DUF6175) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 1.5 8.1e-06 0.069 35 101 .. 44 109 .. 30 115 .. 0.80 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 8.1e-06 DUF6175 35 ykkaleedeelllviskikelmaergfplkdlesklkslkreeaedsvltsksGaglaespl.dkllk 101 ++k l+e+eel++visk +e + e++ lk l+++l++ ++e d+ +k +e++l +kl++ FUN_002360-T1 44 LRKDLRENEELKQVISKQNETILEQESRLKVLQAQLDDCRARELKDMKEHQK--YTEREDKLmEKLKE 109 7899***************************************999944444..33344444466655 PP >> CC_STIL STIL coiled coil region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.8 8e-06 0.068 7 20 .. 65 78 .. 64 80 .. 0.92 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 8e-06 CC_STIL 7 LleQDrQLklLQAQ 20 +leQ+ +Lk+LQAQ FUN_002360-T1 65 ILEQESRLKVLQAQ 78 58************ PP >> DUF4407 Domain of unknown function (DUF4407) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.7 2.5 0.00016 1.3 105 206 .. 4 116 .. 2 145 .. 0.80 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.00016 DUF4407 105 FekeIdqeldeekneeadaakaqlaqa................lraelaelqaqiaalqaeidaaekeldelqkearcelegtkgtgttgvpGkGp 184 F+++Id++l+++++e a+aa+++ + e +el++ i++ +++i + e++l+ lq+++++ + +++ + + FUN_002360-T1 4 FKDSIDTTLATKAEEVASAAIQSAELIkrlkedlfesfgclrkDLRENEELKQVISKQNETILEQESRLKVLQAQLDDCRAR-----ELKDMKEHQ 94 99************9999997776655999999****999776445667788999999999999999999999999954444.....334556678 PP DUF4407 185 eakekeeeldaaqaelaalqak 206 + e+e++l+++ +e+ ++q + FUN_002360-T1 95 KYTEREDKLMEKLKEISSMQVN 116 8999999999999999988876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (606 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2146 (0.0840086); expected 510.9 (0.02) Passed bias filter: 726 (0.0284204); expected 510.9 (0.02) Passed Vit filter: 58 (0.0022705); expected 25.5 (0.001) Passed Fwd filter: 6 (0.00023488); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.39u 0.37s 00:00:00.76 Elapsed: 00:00:00.41 # Mc/sec: 5939.12 // Query: FUN_002361-T1 [L=121] Description: FUN_002361 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (121 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1332 (0.0521433); expected 510.9 (0.02) Passed bias filter: 575 (0.0225093); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.40 # Mc/sec: 1230.73 // Query: FUN_002362-T1 [L=228] Description: FUN_002362 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-29 104.5 3.4 1.1e-29 104.5 3.4 1.4 2 HDNR Domain of unknown function with conserved HDNR moti Domain annotation for each model (and alignments): >> HDNR Domain of unknown function with conserved HDNR motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 104.5 3.4 4.4e-34 1.1e-29 11 175 .. 5 182 .. 2 190 .. 0.85 2 ? -3.3 0.0 0.5 1.3e+04 113 132 .. 200 219 .. 196 223 .. 0.61 Alignments for each domain: == domain 1 score: 104.5 bits; conditional E-value: 4.4e-34 HDNR 11 ldkdgrWfphiGltqktlessTraalkepvsqrlskqvekklPkiykvrekqavnrefpfSvHDNRhalensg...eyfdsGlGrkKisp.ekrQH 102 d g Wfp G+ +++ +s+ r+++++p++ r+++ + P+++ ++ +++nr+ +fS+HDNRha++++g +yf++G+G++K ++ ++QH FUN_002362-T1 5 YDIRGTWFP-SGF-HGHFRSKSRSEFNIPYRHRAKPVP----PEKFLNYAAERSNRH-LFSRHDNRHAHSDMGdleTYFGMGMGKRKQLQsGQTQH 93 57789****.9**.***********************9....***************.***************9999**********99769**** PP HDNR 103 ..ssrnfnlwacdevPsvl.......dgfsnyqisyvhkeavvsps....fRRfprayseisr..qalvwlafke.deeksateflgkk 175 s+r++++w+++e P s + +++ e + ++s +RR+ ra+s+++ ++ ++la++e de++ ++++g + FUN_002362-T1 94 skSTRDIITWRGNECPNPTstyrsdyPTTSRNVTNFNETEPIHVRSnlglRRRQFRAASAPPSqrRTAPLLAWNEpDEAQHGKPGVGLR 182 999***********9976655666443444566666666666655556669********998734458888****99999999999876 PP == domain 2 score: -3.3 bits; conditional E-value: 0.5 HDNR 113 devPsvldgfsnyqisyvhk 132 + +Ps +++ s + ++ FUN_002362-T1 200 HTTPSAVKSQSTVNDNFTVS 219 55667766666655555444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (228 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 399 (0.0156195); expected 510.9 (0.02) Passed bias filter: 283 (0.0110785); expected 510.9 (0.02) Passed Vit filter: 11 (0.000430613); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.30u 0.35s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 2272.56 // Query: FUN_002363-T1 [L=406] Description: FUN_002363 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.4e-26 91.4 0.0 6.2e-23 82.0 0.0 2.2 2 Pkinase Protein kinase domain 1.3e-16 61.2 0.0 5.3e-16 59.2 0.0 1.7 2 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.0094 15.2 0.0 0.017 14.3 0.0 1.3 1 Pkinase_fungal Fungal protein kinase ------ inclusion threshold ------ 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 ABC1 ABC1 atypical kinase-like domain 0.51 10.9 3.2 1 9.9 3.2 1.4 1 Herpes_capsid Gammaherpesvirus capsid protein Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.0 0.0 1.2e-26 6.2e-23 1 150 [. 166 314 .. 166 319 .. 0.88 2 ! 8.0 0.0 0.00046 2.4 175 257 .. 317 390 .. 313 393 .. 0.66 Alignments for each domain: == domain 1 score: 82.0 bits; conditional E-value: 1.2e-26 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkga.. 94 y ++e G G+fgk+y a ++++ +++iKk + + ++ + + k+ + ++iv ++++ e ++ y+++E+++gg++ +l+++k+a FUN_002363-T1 166 YDIIEDAGYGAFGKCYVASKSSDPTLFCIKKCQYKVNEILA-------LYLAKTENIKEIVDFYGAKLEGRNAYICMEFMTGGTISELVEEKKAgi 254 5677888*************************998666544.......56777777999*******************************665332 PP Pkinase 95 ...lseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakeles 150 +se+++ +l+ il+gl++l +g+vHrD+K +N+L+d + + K+tDFG a+ +++ FUN_002363-T1 255 wpiISEDTCFVFLEDILKGLKFLNGKGLVHRDIKGDNVLLDeARIHAKLTDFGSAEDIQE 314 4459*************************************66778**********9987 PP == domain 2 score: 8.0 bits; conditional E-value: 0.00046 Pkinase 175 gkkvDvWslGvilyelltgkp.pfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeell 257 g++ D+W G++ +e+l+g+ p+ + k+ + + ++ + ++ps+ +ee +ll+ + + + ++a+e+l FUN_002363-T1 317 GSSDDIWRTGCLHLEMLNGERlPLFGVKSGG---LQR-------RSSVQPDKHFPSQAKEETNELLNLFFGINRDYMPSATEIL 390 6788**************9852333222222...122.......2245567777788888888888777777777777777766 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.2 0.0 1e-19 5.3e-16 5 153 .. 170 313 .. 166 320 .. 0.83 2 ? -0.5 0.0 0.17 8.7e+02 185 253 .. 320 388 .. 317 392 .. 0.80 Alignments for each domain: == domain 1 score: 59.2 bits; conditional E-value: 1e-19 PK_Tyr_Ser-Thr 5 eklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk.... 95 e+ G GafG+ y + + ++ + ++K+++ + +e + l k+ + ++iv ++g+ +e+++ +i +e+++gG+++e +++k FUN_002363-T1 170 EDAGYGAFGKCYVASKS----SDPTLFCIKKCQYKVNEI------LALYLAKTENIKEIVDFYGAKLEGRNAYICMEFMTGGTISELVEEKkagi 254 56688888888887766....778888899885555554......2334445558899*********************************5554 PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekk.vvkisDfGLardve 153 +s ++ + + +i kG+++L+ k lvHrd+ NvL++e + ++k++DfG a+d++ FUN_002363-T1 255 WPIISEDTCFVFLEDILKGLKFLNGKGLVHRDIKGDNVLLDEARiHAKLTDFGSAEDIQ 313 4567889999*******************************97769*******999985 PP == domain 2 score: -0.5 bits; conditional E-value: 0.17 PK_Tyr_Ser-Thr 185 sDvWsfGvllwEiftlgeepykglkneevlelleegerleqpencpeelyelmkeCweedpeeRptfke 253 D+W G l E+++ + p+ g+k+ + ++ + + + p++++ee +el++ + + + p+ +e FUN_002363-T1 320 DDIWRTGCLHLEMLNGERLPLFGVKSGGLQRRSSVQPDKHFPSQAKEETNELLNLFFGINRDYMPSATE 388 59*************888999999999988888888888888888888888887776666666666555 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 3.4e-06 0.017 284 356 .. 259 327 .. 248 335 .. 0.84 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 3.4e-06 Pkinase_fungal 284 skkeLLealrdaikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielse.ssasgarertGT 356 s+ + l+d +k+++ L +g++HrDI N+++ e++ + L D+ a +++e ++s++ rtG FUN_002363-T1 259 SEDTCFVFLEDILKGLKFLN-GKGLVHRDIKGDNVLLD----EARIHAKLTDFGSAEDIQEpGGSSDDIWRTGC 327 555667789**********9.9***************9....55788999999999999997777777788886 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 3.8e-06 0.019 144 220 .. 231 314 .. 227 317 .. 0.88 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.8e-06 ABC1 144 rvLtmeyvdGikiddlealeeagidrkeiaeklvelfleqife.......dgffhaDphpGNllvrkdg.elvllDfGlmgelde 220 ++ me++ G i++l + ++agi + i+e+ + +fle i++ +g++h D N+l+++++ + l DfG ++++e FUN_002363-T1 231 AYICMEFMTGGTISELVEEKKAGIWP-IISEDTCFVFLEDILKglkflngKGLVHRDIKGDNVLLDEARiHAKLTDFGSAEDIQE 314 5789****************999976.79**********99875555555799**************999999******999976 PP >> Herpes_capsid Gammaherpesvirus capsid protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 3.2 0.0002 1 94 148 .. 77 133 .. 66 139 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0002 Herpes_capsid 94 afealsltvPlrPetaegttgGgsds..sasGasGgsastlsSgpsslaaasglssg 148 ++eal +P++P + +t g as +s +s+ + Sg+ssl++ s +ss FUN_002363-T1 77 SLEALLEKLPSPPSHHPDDTKDGATCstIASAPSTSSVHRAFSGGSSLSTRSIASSD 133 688899999****999988864443324799******************99987765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (406 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 822 (0.0321785); expected 510.9 (0.02) Passed bias filter: 675 (0.026424); expected 510.9 (0.02) Passed Vit filter: 41 (0.00160501); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.33u 0.42s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 3899.94 // Query: FUN_002363-T2 [L=406] Description: FUN_002363 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-25 89.8 0.0 6.2e-23 82.0 0.0 2.2 2 Pkinase Protein kinase domain 2.5e-16 60.3 0.0 4.5e-16 59.4 0.0 1.4 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.0063 15.8 0.0 0.011 14.9 0.0 1.3 1 Pkinase_fungal Fungal protein kinase 0.0097 15.6 0.0 0.019 14.6 0.0 1.4 1 ABC1 ABC1 atypical kinase-like domain ------ inclusion threshold ------ 0.46 11.0 3.2 1 9.9 3.2 1.5 1 Herpes_capsid Gammaherpesvirus capsid protein Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.0 0.0 1.2e-26 6.2e-23 1 150 [. 166 314 .. 166 319 .. 0.88 2 ! 6.4 0.0 0.0014 7.2 175 197 .. 317 339 .. 313 393 .. 0.58 Alignments for each domain: == domain 1 score: 82.0 bits; conditional E-value: 1.2e-26 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdllsrkga.. 94 y ++e G G+fgk+y a ++++ +++iKk + + ++ + + k+ + ++iv ++++ e ++ y+++E+++gg++ +l+++k+a FUN_002363-T2 166 YDIIEDAGYGAFGKCYVASKSSDPTLFCIKKCQYKVNEILA-------LYLAKTENIKEIVDFYGAKLEGRNAYICMEFMTGGTISELVEEKKAgi 254 5677888*************************998666544.......56777777999*******************************665332 PP Pkinase 95 ...lseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakeles 150 +se+++ +l+ il+gl++l +g+vHrD+K +N+L+d + + K+tDFG a+ +++ FUN_002363-T2 255 wpiISEDTCFVFLEDILKGLKFLNGKGLVHRDIKGDNVLLDeARIHAKLTDFGSAEDIQE 314 4459*************************************66778**********9987 PP == domain 2 score: 6.4 bits; conditional E-value: 0.0014 Pkinase 175 gkkvDvWslGvilyelltgkppf 197 g++ D+W G++ +e+l+g++ FUN_002363-T2 317 GSSDDIWRTGCLHLEMLNGESSH 339 6788**************98643 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.4 0.0 8.9e-20 4.5e-16 5 154 .. 170 314 .. 166 328 .. 0.83 Alignments for each domain: == domain 1 score: 59.4 bits; conditional E-value: 8.9e-20 PK_Tyr_Ser-Thr 5 eklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk.... 95 e+ G GafG+ y + + ++ + ++K+++ + +e + l k+ + ++iv ++g+ +e+++ +i +e+++gG+++e +++k FUN_002363-T2 170 EDAGYGAFGKCYVASKS----SDPTLFCIKKCQYKVNEI------LALYLAKTENIKEIVDFYGAKLEGRNAYICMEFMTGGTISELVEEKkagi 254 56688888888887766....778888899885555554......2334445558899*********************************5554 PP PK_Tyr_Ser-Thr 96 keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekk.vvkisDfGLardvek 154 +s ++ + + +i kG+++L+ k lvHrd+ NvL++e + ++k++DfG a+d+++ FUN_002363-T2 255 WPIISEDTCFVFLEDILKGLKFLNGKGLVHRDIKGDNVLLDEARiHAKLTDFGSAEDIQE 314 4567889999*******************************97769*******9999954 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.9 0.0 2.2e-06 0.011 284 357 .. 259 328 .. 248 341 .. 0.82 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 2.2e-06 Pkinase_fungal 284 skkeLLealrdaikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielse.ssasgarertGTl 357 s+ + l+d +k+++ L +g++HrDI N+++ e++ + L D+ a +++e ++s++ rtG l FUN_002363-T2 259 SEDTCFVFLEDILKGLKFLN-GKGLVHRDIKGDNVLLD----EARIHAKLTDFGSAEDIQEpGGSSDDIWRTGCL 328 555667789**********9.9***************9....558889999999999999977777888888875 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 3.8e-06 0.019 144 220 .. 231 314 .. 227 317 .. 0.88 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.8e-06 ABC1 144 rvLtmeyvdGikiddlealeeagidrkeiaeklvelfleqife.......dgffhaDphpGNllvrkdg.elvllDfGlmgelde 220 ++ me++ G i++l + ++agi + i+e+ + +fle i++ +g++h D N+l+++++ + l DfG ++++e FUN_002363-T2 231 AYICMEFMTGGTISELVEEKKAGIWP-IISEDTCFVFLEDILKglkflngKGLVHRDIKGDNVLLDEARiHAKLTDFGSAEDIQE 314 5789****************999976.79**********99875555555799**************999999******999976 PP >> Herpes_capsid Gammaherpesvirus capsid protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 3.2 0.0002 1 94 148 .. 77 133 .. 66 139 .. 0.83 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0002 Herpes_capsid 94 afealsltvPlrPetaegttgGgsds..sasGasGgsastlsSgpsslaaasglssg 148 ++eal +P++P + +t g as +s +s+ + Sg+ssl++ s +ss FUN_002363-T2 77 SLEALLEKLPSPPSHHPDDTKDGATCstIASAPSTSSVHRAFSGGSSLSTRSIASSD 133 688899999****999988864443324799******************99987765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (406 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 825 (0.0322959); expected 510.9 (0.02) Passed bias filter: 680 (0.0266197); expected 510.9 (0.02) Passed Vit filter: 43 (0.0016833); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.39s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3971.09 // Query: FUN_002364-T1 [L=396] Description: FUN_002364 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.3e-05 22.4 2.0 49 3.7 0.0 6.3 7 Peripla_BP_2 Periplasmic binding protein 0.00042 21.2 0.1 2.4e+02 2.6 0.0 5.5 6 DUF8158 Domain of unknown function (DUF8158) 0.0067 17.3 0.3 88 4.0 0.0 4.9 7 TraC TraC-like protein Domain annotation for each model (and alignments): >> Peripla_BP_2 Periplasmic binding protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.035 3e+02 44 61 .. 57 74 .. 41 74 .. 0.72 2 ? 2.0 0.0 0.019 1.6e+02 39 61 .. 90 112 .. 74 113 .. 0.67 3 ? 1.9 0.0 0.019 1.7e+02 39 61 .. 128 150 .. 112 150 .. 0.67 4 ? 1.5 0.0 0.026 2.2e+02 39 61 .. 166 188 .. 150 189 .. 0.67 5 ? 1.4 0.0 0.028 2.4e+02 39 61 .. 204 226 .. 189 227 .. 0.68 6 ? 2.0 0.0 0.019 1.6e+02 39 61 .. 242 264 .. 226 265 .. 0.67 7 ! 3.7 0.0 0.0058 49 39 61 .. 280 302 .. 264 312 .. 0.73 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.035 Peripla_BP_2 44 gadgeinvErlaalkPDl 61 +i++E+++al PD+ FUN_002364-T1 57 SGEENISLEKMLALCPDV 74 455678999999999997 PP == domain 2 score: 2.0 bits; conditional E-value: 0.019 Peripla_BP_2 39 evvkvgadgeinvErlaalkPDl 61 + + +i++E+++al PD+ FUN_002364-T1 90 SASTGSGEENISLEKMLALCPDV 112 44445556789999***999997 PP == domain 3 score: 1.9 bits; conditional E-value: 0.019 Peripla_BP_2 39 evvkvgadgeinvErlaalkPDl 61 + + +i++E+++al PD+ FUN_002364-T1 128 SASTGSGEENISLEKMLALCPDV 150 4444555678999******9997 PP == domain 4 score: 1.5 bits; conditional E-value: 0.026 Peripla_BP_2 39 evvkvgadgeinvErlaalkPDl 61 + + +i++E+++al PD+ FUN_002364-T1 166 SASTGSGEENISLEKMLALFPDV 188 44445556789999999999997 PP == domain 5 score: 1.4 bits; conditional E-value: 0.028 Peripla_BP_2 39 evvkvgadgeinvErlaalkPDl 61 + + +i++E+++al PD+ FUN_002364-T1 204 SASTGSGEENISLEKMLALFPDV 226 44445556789999999999997 PP == domain 6 score: 2.0 bits; conditional E-value: 0.019 Peripla_BP_2 39 evvkvgadgeinvErlaalkPDl 61 + + +i++E+++al PD+ FUN_002364-T1 242 SASTGSGEENISLEKMLALCPDV 264 44445556789999***999997 PP == domain 7 score: 3.7 bits; conditional E-value: 0.0058 Peripla_BP_2 39 evvkvgadgeinvErlaalkPDl 61 + + +i++E+++al PD+ FUN_002364-T1 280 SASTGSGEENISFEKMLALCPDV 302 444555567899*********98 PP >> DUF8158 Domain of unknown function (DUF8158) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.6 0.0 0.028 2.4e+02 19 51 .. 61 93 .. 51 100 .. 0.84 2 ? 2.4 0.0 0.033 2.8e+02 19 50 .. 99 130 .. 91 134 .. 0.83 3 ? 2.5 0.0 0.03 2.6e+02 19 51 .. 137 169 .. 129 176 .. 0.84 4 ? 1.7 0.0 0.056 4.8e+02 19 50 .. 175 206 .. 168 209 .. 0.81 5 ? 1.7 0.0 0.053 4.5e+02 19 50 .. 213 244 .. 206 249 .. 0.82 6 ? 2.4 0.0 0.032 2.8e+02 19 50 .. 251 282 .. 243 287 .. 0.84 Alignments for each domain: == domain 1 score: 2.6 bits; conditional E-value: 0.028 DUF8158 19 hasvddvieLvleRaadpReehqdahfDeavaa 51 s+++++ L + +pR+e +d++ De+ ++ FUN_002364-T1 61 NISLEKMLALCPDVPSNPRNETKDGDTDESAST 93 568889999999999*************98765 PP == domain 2 score: 2.4 bits; conditional E-value: 0.033 DUF8158 19 hasvddvieLvleRaadpReehqdahfDeava 50 s+++++ L + +pR+e +d++ De+ + FUN_002364-T1 99 NISLEKMLALCPDVPSNPRNETKDGDTDESAS 130 5688889999999999************9876 PP == domain 3 score: 2.5 bits; conditional E-value: 0.03 DUF8158 19 hasvddvieLvleRaadpReehqdahfDeavaa 51 s+++++ L + +pR+e +d++ De+ ++ FUN_002364-T1 137 NISLEKMLALCPDVPSNPRNETKDGDTDESAST 169 5688889999999999************98765 PP == domain 4 score: 1.7 bits; conditional E-value: 0.056 DUF8158 19 hasvddvieLvleRaadpReehqdahfDeava 50 s+++++ L + +pR+e +d++ De+ + FUN_002364-T1 175 NISLEKMLALFPDVPSNPRNETKDGDTDESAS 206 4577888888888899************9876 PP == domain 5 score: 1.7 bits; conditional E-value: 0.053 DUF8158 19 hasvddvieLvleRaadpReehqdahfDeava 50 s+++++ L + +pR+e +d++ De+ + FUN_002364-T1 213 NISLEKMLALFPDVPSNPRNETKDGDTDESAS 244 4577888888888899************9876 PP == domain 6 score: 2.4 bits; conditional E-value: 0.032 DUF8158 19 hasvddvieLvleRaadpReehqdahfDeava 50 s+++++ L + +pR+e +d++ De+ + FUN_002364-T1 251 NISLEKMLALCPDVPSNPRNETKDGDTDESAS 282 5688889999999999************9876 PP >> TraC TraC-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.088 7.5e+02 36 75 .. 55 94 .. 34 105 .. 0.85 2 ? 0.8 0.1 0.11 9.1e+02 36 75 .. 93 132 .. 81 139 .. 0.85 3 ? 0.8 0.0 0.11 9.4e+02 36 75 .. 131 170 .. 118 176 .. 0.85 4 ? 4.0 0.0 0.011 92 36 75 .. 169 208 .. 165 213 .. 0.89 5 ? 4.0 0.0 0.01 88 36 75 .. 207 246 .. 204 253 .. 0.88 6 ? 0.6 0.1 0.12 1.1e+03 36 75 .. 245 284 .. 240 290 .. 0.85 7 ? 1.0 0.0 0.091 7.8e+02 36 73 .. 283 320 .. 269 335 .. 0.79 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.088 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAaas 75 +G +e +i e++++ ++ + R+ k g + +A++ FUN_002364-T1 55 TGSGEENISLEKMLALCPDVPSNPRNETKDGDTDESASTG 94 5778889999999999999999999999999999998876 PP == domain 2 score: 0.8 bits; conditional E-value: 0.11 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAaas 75 +G +e +i e++++ ++ + R+ k g + +A++ FUN_002364-T1 93 TGSGEENISLEKMLALCPDVPSNPRNETKDGDTDESASTG 132 5778889999999999999999999999999999998875 PP == domain 3 score: 0.8 bits; conditional E-value: 0.11 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAaas 75 +G +e +i e++++ ++ + R+ k g + +A++ FUN_002364-T1 131 TGSGEENISLEKMLALCPDVPSNPRNETKDGDTDESASTG 170 5778888999999999999999999999999999998875 PP == domain 4 score: 4.0 bits; conditional E-value: 0.011 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAaas 75 +G +e +i e++++ f ++ + R+ k g + +A++ FUN_002364-T1 169 TGSGEENISLEKMLALFPDVPSNPRNETKDGDTDESASTG 208 5788999999*****************9999999999986 PP == domain 5 score: 4.0 bits; conditional E-value: 0.01 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAaas 75 +G +e +i e++++ f ++ + R+ k g + +A++ FUN_002364-T1 207 TGSGEENISLEKMLALFPDVPSNPRNETKDGDTDESASTG 246 5788999999*****************9999999999986 PP == domain 6 score: 0.6 bits; conditional E-value: 0.12 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAaas 75 +G +e +i e++++ ++ + R+ k g + +A++ FUN_002364-T1 245 TGSGEENISLEKMLALCPDVPSNPRNETKDGDTDESASTG 284 5778889999999999999999999999999999999876 PP == domain 7 score: 1.0 bits; conditional E-value: 0.091 TraC 36 sGLaeleieeeeldrifeEiaaRFRkaekkgkatakAa 73 +G +e +i e++++ ++ + R+ +k g++ ++A FUN_002364-T1 283 TGSGEENISFEKMLALCPDVPSILRNEQKDGATCTTAK 320 57788899999999999999999999999998877774 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (396 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 290 (0.0113525); expected 510.9 (0.02) Passed bias filter: 224 (0.00876884); expected 510.9 (0.02) Passed Vit filter: 15 (0.000587199); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.29u 0.39s 00:00:00.68 Elapsed: 00:00:00.39 # Mc/sec: 4076.06 // Query: FUN_002365-T1 [L=159] Description: FUN_002365 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (159 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 843 (0.0330006); expected 510.9 (0.02) Passed bias filter: 572 (0.0223919); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.43s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1603.36 // Query: FUN_002365-T2 [L=203] Description: FUN_002365 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 12.3 0.1 0.29 11.4 0.1 1.5 1 WH2 WH2 motif Domain annotation for each model (and alignments): >> WH2 WH2 motif # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 1.1e-05 0.29 2 17 .. 162 177 .. 161 177 .. 0.91 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 1.1e-05 WH2 2 gggRgaLLadIraGkq 17 + +R LL++Ir+G+q FUN_002365-T2 162 DMDRKSLLEQIRSGIQ 177 679***********98 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (203 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1128 (0.0441574); expected 510.9 (0.02) Passed bias filter: 700 (0.0274026); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.40s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2009.95 // Query: FUN_002366-T1 [L=378] Description: FUN_002366 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-19 70.4 0.0 9.2e-19 68.3 0.0 1.9 2 Pkinase Protein kinase domain 2.5e-14 53.7 0.0 3.4e-14 53.3 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase ------ inclusion threshold ------ 0.095 11.9 0.0 0.34 10.1 0.0 1.7 2 Pkinase_fungal Fungal protein kinase 0.36 10.5 3.0 0.55 9.9 3.0 1.2 1 TipE Na+ channel auxiliary subunit TipE 0.41 10.9 0.4 0.84 9.8 0.2 1.5 2 APH Phosphotransferase enzyme family Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 68.3 0.0 1.8e-22 9.2e-19 1 151 [. 138 290 .. 138 300 .. 0.87 2 ? -0.4 0.0 0.16 8.4e+02 179 195 .. 296 312 .. 292 352 .. 0.76 Alignments for each domain: == domain 1 score: 68.3 bits; conditional E-value: 1.8e-22 Pkinase 1 yevleklGeGsfgkVykavek..etgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdlls.... 90 y+++ +G G++g++y+a + +++ +++iK+ e ++ +++ k+ + ++iv ++++ + ++ y+++Ey+ gg++ +l+ FUN_002366-T1 138 YHIIAVIGYGAYGTCYTASKIagSSQPEFVIKECPYEVNELLA-------LSLAKEKQVMEIVDFYGAKLRGRSAYICMEYMAGGTILELVPtpvr 226 788999**********998762257789*******99887655.......57777777789*************************9999888886 PP Pkinase 91 ..rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakeless 151 + ++ ee++ +++k +l+g e+l +g+vH D+K +N+L+d + + K+tDFG ak +++s FUN_002366-T1 227 agAWPIIAEETCFFVVKDVLKGEEFLNINGLVHGDIKADNVLLDeHCIHAKLTDFGSAKSIRES 290 5444469*************************************55567**********99876 PP == domain 2 score: -0.4 bits; conditional E-value: 0.16 Pkinase 179 DvWslGvilyelltgkp 195 D W G++ + +l+gk FUN_002366-T1 296 DTWKTGCLYLFMLNGKI 312 99***********9984 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.3 0.0 6.7e-18 3.4e-14 3 154 .. 140 289 .. 138 301 .. 0.89 Alignments for each domain: == domain 1 score: 53.3 bits; conditional E-value: 6.7e-18 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk.. 95 + +G Ga+G+ y + +++ + ++K + e +e ++ +e ++m +iv ++g+ +++++ +i +ey++gG+++e + + FUN_002366-T1 140 IIAVIGYGAYGTCYTASKI--AGSSQPEFVIKECPYEVNELLALSLAKEKQVM------EIVDFYGAKLRGRSAYICMEYMAGGTILELVPTPvr 226 66789**********9988..78889999*****9999998888888888888......69****************************999988 PP PK_Tyr_Ser-Thr 96 ...keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekk.vvkisDfGLardvek 154 + ++ + +++++ kG e+L+ + lvH d+ a NvL++e+ ++k++DfG a+++++ FUN_002366-T1 227 agaWPIIAEETCFFVVKDVLKGEEFLNINGLVHGDIKADNVLLDEHCiHAKLTDFGSAKSIRE 289 87656677788889999***************************987689******9999944 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.2 1e+03 160 205 .. 151 196 .. 142 199 .. 0.76 2 ? 10.1 0.0 6.7e-05 0.34 290 356 .. 240 302 .. 224 310 .. 0.80 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.2 Pkinase_fungal 160 tcwrakrsdsk...eyviKdsWqdesrkeEaelLkeaeergvegvarlv 205 tc+ a++ e+viK + +E L +a+e++v +++ ++ FUN_002366-T1 151 TCYTASKIAGSsqpEFVIKECPY---EVNELLALSLAKEKQVMEIVDFY 196 79998875544578999998744...34799999999999999998876 PP == domain 2 score: 10.1 bits; conditional E-value: 6.7e-05 Pkinase_fungal 290 ealrdaikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielsessas.garertGT 356 + +d++k+ + L +g++H+DI + N+++ e+ + L D+ a+++ es+ s ++ +tG FUN_002366-T1 240 FVVKDVLKGEEFLN-INGLVHGDIKADNVLLDEH----CIHAKLTDFGSAKSIRESGGSfDDTWKTGC 302 5789999**99998.9***************955....667888899999888885544244666665 PP >> TipE Na+ channel auxiliary subunit TipE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 3.0 0.00011 0.55 347 422 .. 10 86 .. 3 99 .. 0.77 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.00011 TipE 347 ndnkidavneseaa.vtanhinennvdtaGstiindasttattpvqqllpnGtansstnisqtntnttattntnGss 422 n++ ++++ ++ ++ n + +n+ +aGs++++ + +t ++qllpn + s +i +++t++ +tt+ +Gs FUN_002366-T1 10 NEDTVQKKPDTSVTnSENNTLTRDNTTNAGSEVESVVRATLPDELEQLLPNPPSFSPKDIRDGETTAMSTTSEAGSG 86 4444444433333303344556688999***********************************************96 PP >> APH Phosphotransferase enzyme family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.2 0.0 1.6 8.1e+03 40 85 .. 174 219 .. 169 227 .. 0.58 2 ? 9.8 0.2 0.00017 0.84 169 186 .. 256 272 .. 253 285 .. 0.82 Alignments for each domain: == domain 1 score: -3.2 bits; conditional E-value: 1.6 APH 40 elallrhLaaagvvpvPrvlagetdaellglpfllmeylpGedler 85 e+++l +L+ a +v +++++ ++ mey++G ++ + FUN_002366-T1 174 EVNELLALSLAKEKQVMEIVDFYGAKLRGRSAYICMEYMAGGTILE 219 5555555553322366677766544444444777788888777655 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00017 APH 169 vlvHgDlhpgNllvddgg 186 +lvHgD++ +N+l+d+ + FUN_002366-T1 256 GLVHGDIKADNVLLDE-H 272 79*************4.3 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (378 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 631 (0.0247015); expected 510.9 (0.02) Passed bias filter: 502 (0.0196516); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.34u 0.37s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 3643.77 // Query: FUN_002367-T1 [L=100] Description: FUN_002367 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 666 (0.0260716); expected 510.9 (0.02) Passed bias filter: 514 (0.0201214); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.41s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1001.88 // Query: FUN_002369-T1 [L=104] Description: FUN_002369 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 1.8 9.2 6.6 0.61 10.7 1.5 2.2 2 FYVE_CARP1-2 E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD z Domain annotation for each model (and alignments): >> FYVE_CARP1-2 E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 1.5 2.4e-05 0.61 9 29 .. 4 26 .. 2 34 .. 0.79 2 ? 1.0 0.3 0.027 6.8e+02 22 30 .. 61 69 .. 47 78 .. 0.77 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 2.4e-05 FYVE_CARP1-2 9 nssRkhiClDCkknFC..tsCss 29 ns +C DCk n t+Css FUN_002369-T1 4 NSKTTWVCSDCKVNLAspTTCSS 26 555559********974479*98 PP == domain 2 score: 1.0 bits; conditional E-value: 0.027 FYVE_CARP1-2 22 nFCtsCssq 30 nF t+C s FUN_002369-T1 61 NFPTTCPST 69 999999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (104 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1213 (0.0474848); expected 510.9 (0.02) Passed bias filter: 565 (0.0221178); expected 510.9 (0.02) Passed Vit filter: 55 (0.00215306); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1067.58 // Query: FUN_002370-T1 [L=191] Description: FUN_002370 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.14 13.1 0.5 0.25 12.3 0.5 1.4 1 Rnk_N Rnk N-terminus Domain annotation for each model (and alignments): >> Rnk_N Rnk N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.5 9.9e-06 0.25 7 21 .. 153 168 .. 151 178 .. 0.78 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 9.9e-06 Rnk_N 7 slDleRLeaLlesl.p 21 s Dl+RLe+L++s FUN_002370-T1 153 SEDLDRLESLADSYfS 168 89**********8753 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (191 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 767 (0.0300254); expected 510.9 (0.02) Passed bias filter: 442 (0.0173028); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1906.44 // Query: FUN_002371-T1 [L=250] Description: FUN_002371 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-06 26.4 0.0 0.00014 21.9 0.0 2.2 2 Pkinase Protein kinase domain 5.3e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase ------ inclusion threshold ------ 0.081 13.7 0.0 0.14 12.9 0.0 1.4 1 Orf78 Orf78 (ac78) 0.18 12.1 0.6 3.3 8.0 0.0 2.6 3 HTH_78 Domain of unknown function Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 2.1e-08 0.00014 58 124 .. 8 80 .. 2 83 .. 0.91 2 ? 2.1 0.0 0.023 1.5e+02 179 255 .. 109 176 .. 100 180 .. 0.68 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 2.1e-08 Pkinase 58 pnivrlidvfeekdelylvlEyveggelfdlls.....rkgalseeeakkilkqilegleylH.segvvHrDl 124 p+ v +++++ + ++ ++++E++ gg+l++l++ +kg l ee++ ++ k i+e+ ++lH + g+ H D+ FUN_002371-T1 8 PQTVGYLGAILQGRSAVIFMELMAGGTLEQLVKkrmedKKGPLLEETCLNFGKDIFEAQKFLHeKVGMAHNDI 80 6678899999999*******************9999988999*********************6668*****8 PP == domain 2 score: 2.1 bits; conditional E-value: 0.023 Pkinase 179 DvWslGvilyelltgkp..pfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaee 255 D W ++l+ +l+gk +f ++ +++ +++ ++ + ++p + see+++ll++++ + +kk ++ e FUN_002371-T1 109 DTWKGNCLLLFMLNGKRshLFFEKLDED---GQYE--------GVDPEKEFPPKASEEMIELLTSIFGVGQKKLPSEAE 176 7777778888888876411333222222...1222........356688999999*********999988888777555 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 1.8e-08 0.00011 60 128 .. 7 80 .. 2 83 .. 0.91 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.8e-08 PK_Tyr_Ser-Thr 60 hpnivkllgvcteeepllivteyvegGsLkefLrkk....keklslkellklalqiAkGmeyLesk.klvHrdl 128 +p+ v +lg+++++++ +i +e+++gG+L++ ++k+ k +l ++ l++ ++i ++ ++L++k + H d+ FUN_002371-T1 7 NPQTVGYLGAILQGRSAVIFMELMAGGTLEQLVKKRmedkKGPLLEETCLNFGKDIFEAQKFLHEKvGMAHNDI 80 5788999***********************999999888899999******************99835889987 PP >> Orf78 Orf78 (ac78) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 2.3e-05 0.14 41 84 .. 208 250 .] 192 250 .] 0.73 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 2.3e-05 Orf78 41 svaakneieekesnaekasalnillisllavvcvlvllyviyYf 84 s+a+ ++ +ek++ +++ ++++++++ll ++++l+l y yYf FUN_002371-T1 208 STADARRFNEKKA-MHRVRKTSVVVTGLLGLLVILILSYFYYYF 250 3333344444433.5788899********************999 PP >> HTH_78 Domain of unknown function # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.1 1.1 7e+03 17 19 .. 38 40 .. 20 48 .. 0.51 2 ? 8.0 0.0 0.00052 3.3 23 47 .. 57 81 .. 50 85 .. 0.83 3 ? 1.2 0.0 0.067 4.3e+02 27 44 .. 152 169 .. 150 179 .. 0.86 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 1.1 HTH_78 17 mvk 19 +vk FUN_002371-T1 38 LVK 40 333 PP == domain 2 score: 8.0 bits; conditional E-value: 0.00052 HTH_78 23 enGkskeeiiefLvkkvGlnkkDAe 47 + Gk e +fL +kvG+ ++D FUN_002371-T1 57 NFGKDIFEAQKFLHEKVGMAHNDIH 81 5677777899************976 PP == domain 3 score: 1.2 bits; conditional E-value: 0.067 HTH_78 27 skeeiiefLvkkvGlnkk 44 ee+ie L++ G+++k FUN_002371-T1 152 ASEEMIELLTSIFGVGQK 169 579***********9987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (250 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 910 (0.0356234); expected 510.9 (0.02) Passed bias filter: 734 (0.0287336); expected 510.9 (0.02) Passed Vit filter: 52 (0.00203562); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 2432.11 // Query: FUN_002372-T1 [L=376] Description: FUN_002372 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-23 83.8 0.1 4.2e-23 82.6 0.1 1.7 2 Pkinase Protein kinase domain 5.4e-20 72.3 0.0 9.9e-20 71.4 0.0 1.4 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase ------ inclusion threshold ------ 0.099 13.2 6.1 0.24 11.9 6.1 1.6 1 Nucleoprot-TPR Nucleoprotein TPR-like domain 0.2 12.3 0.0 0.2 12.3 0.0 2.7 5 BET Bromodomain extra-terminal - transcription re 7.4 7.4 7.2 21 5.9 7.2 1.9 1 CCDC-167 Coiled-coil domain-containing protein 167 Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 82.6 0.1 8.1e-27 4.2e-23 1 153 [. 138 293 .. 138 304 .. 0.89 2 ? -3.9 0.0 1.9 9.9e+03 223 246 .. 333 356 .. 322 361 .. 0.70 Alignments for each domain: == domain 1 score: 82.6 bits; conditional E-value: 8.1e-27 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdlls...... 90 y +eklG+G +g +y+a+ + + +++iK+ ++ k++ +++ kk k ++iv ++++ e+ + y+++ +++ g+l+++++ FUN_002372-T1 138 YVLNEKLGSGCSGFCYRATTISGSLTFCIKMCDHIKEEILA-------LTLAKKDKVKYIVDYYGTKLENGTAYICMQFMKRGTLEKHIEqqrekl 226 67899**************************9987665433.......68889999**********************************887766 PP Pkinase 91 ...rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakelesssk 153 + +++e ++ +++ il+g+e+l s+g+vH D+K +N+Lid + ++K++DFGl++++e++ FUN_002372-T1 227 pvgAWPIIDEGTCFNFVGDILKGVEFLNSKGLVHGDIKGDNVLIDeSCTHIKLADFGLSRKIEDHVG 293 66544568888**********************************66677************98765 PP == domain 2 score: -3.9 bits; conditional E-value: 1.9 Pkinase 223 eklpepssiseeakdllkkllkkd 246 ++ ++p + see +dll+ +++ + FUN_002372-T1 333 FQKHFPPQASEETTDLLNIIFASE 356 566777888999999988777665 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 71.4 0.0 1.9e-23 9.9e-20 3 154 .. 140 290 .. 138 308 .. 0.87 Alignments for each domain: == domain 1 score: 71.4 bits; conditional E-value: 1.9e-23 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk.. 95 l+eklG+G G y++t + + + ++K++++ ++e + ++l kk + + iv ++g +e+++ +i +++++ G+L+++++++ FUN_002372-T1 140 LNEKLGSGCSGFCYRATTI----SGSLTFCIKMCDHIKEE------ILALTLAKKDKVKYIVDYYGTKLENGTAYICMQFMKRGTLEKHIEQQre 224 689***************9....999********443333......45677788889************************************66 PP PK_Tyr_Ser-Thr 96 ......keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekk.vvkisDfGLardvek 154 ++ + ++++ +i kG+e+L+sk lvH d+ NvL++e+ ++k++DfGL+r++e+ FUN_002372-T1 225 klpvgaWPIIDEGTCFNFVGDILKGVEFLNSKGLVHGDIKGDNVLIDESCtHIKLADFGLSRKIED 290 666665555677789********************************97549***********943 PP >> Nucleoprot-TPR Nucleoprotein TPR-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 6.1 4.7e-05 0.24 5 39 .. 87 121 .. 85 124 .. 0.93 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 4.7e-05 Nucleoprot-TPR 5 sikarekrleQEkellekqnewLneELkaKteell 39 +++ + k+l++E+ le +n +++ELk Kt+el FUN_002372-T1 87 NAQIEAKQLQDERKQLEEENLCMKSELKRKTNELK 121 678899***************************96 PP >> BET Bromodomain extra-terminal - transcription regulation # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 3.9e-05 0.2 33 57 .. 49 75 .. 41 79 .. 0.79 2 ? -3.4 0.4 3 1.5e+04 9 22 .. 94 107 .. 91 108 .. 0.60 3 ? -3.8 0.2 4 2.1e+04 6 20 .. 109 123 .. 109 124 .. 0.80 4 ? -3.0 0.0 2.3 1.2e+04 10 32 .. 215 237 .. 210 241 .. 0.79 5 ? -2.9 0.0 2.1 1.1e+04 19 30 .. 355 366 .. 354 371 .. 0.83 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 3.9e-05 BET 33 e.pelq.adedEiElDidalddktlrk 57 + + ++ +++dE+ +Di++l+++t ++ FUN_002372-T1 49 KrKRKNpNNNDEMFMDIETLEPATHFE 75 444555699**************9776 PP == domain 2 score: -3.4 bits; conditional E-value: 3 BET 9 eLsekInkLpgekl 22 +L+ + ++L++e+l FUN_002372-T1 94 QLQDERKQLEEENL 107 56666666666665 PP == domain 3 score: -3.8 bits; conditional E-value: 4 BET 6 EKkeLsekInkLpge 20 +K eL++k n+L e FUN_002372-T1 109 MKSELKRKTNELKTE 123 789999999988765 PP == domain 4 score: -3.0 bits; conditional E-value: 2.3 BET 10 LsekInkLpgeklervieIIker 32 L ++I++ ++ + +++ II e FUN_002372-T1 215 LEKHIEQQREKLPVGAWPIIDEG 237 77788888888888899999875 PP == domain 5 score: -2.9 bits; conditional E-value: 2.1 BET 19 geklervieIIk 30 e+l r+++I++ FUN_002372-T1 355 SEQLLRAADILR 366 589999999997 PP >> CCDC-167 Coiled-coil domain-containing protein 167 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.9 7.2 0.0041 21 25 59 .. 88 121 .. 38 122 .. 0.90 Alignments for each domain: == domain 1 score: 5.9 bits; conditional E-value: 0.0041 CCDC-167 25 kklrkeelseedRkeLekeleelkekleknekeLk 59 +++ ++l++e Rk+Le+e +k++l+++ +eLk FUN_002372-T1 88 AQIEAKQLQDE-RKQLEEENLCMKSELKRKTNELK 121 57788888888.**********************8 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (376 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1337 (0.052339); expected 510.9 (0.02) Passed bias filter: 752 (0.0294382); expected 510.9 (0.02) Passed Vit filter: 71 (0.00277941); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.35u 0.36s 00:00:00.71 Elapsed: 00:00:00.40 # Mc/sec: 3768.72 // Query: FUN_002374-T1 [L=80] Description: FUN_002374 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (80 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 822 (0.0321785); expected 510.9 (0.02) Passed bias filter: 583 (0.0228225); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.23u 0.43s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 819.93 // Query: FUN_002375-T1 [L=314] Description: FUN_002375 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (314 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 979 (0.0383245); expected 510.9 (0.02) Passed bias filter: 512 (0.0200431); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 3136.07 // Query: FUN_002376-T1 [L=598] Description: FUN_002376 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-24 87.4 20.9 2e-24 87.0 20.9 1.1 1 7tm_1 7 transmembrane receptor (rhodopsin family) 7.7e-11 42.1 10.3 1.9e-10 40.8 4.7 2.4 2 LRR_8 Leucine rich repeat 8.5e-07 29.5 14.3 1.9e-05 25.2 6.1 2.9 4 LRR_4 Leucine Rich repeats (2 copies) 9.3e-07 29.3 0.9 1e-05 25.9 0.4 2.4 2 LRR_5 BspA type Leucine rich repeat region (6 copies 8.3e-05 22.5 8.2 0.11 13.2 0.7 4.3 3 LRR_1 Leucine Rich Repeat 0.0021 17.3 0.6 0.0041 16.4 0.6 1.4 1 LRR_14 Leucine-rich repeat region ------ inclusion threshold ------ 0.02 15.0 1.0 0.039 14.0 1.0 1.4 1 LRR_9 Leucine-rich repeat 0.038 13.4 6.6 0.058 12.8 5.5 1.7 1 7TM_GPCR_Srab Serpentine type 7TM GPCR receptor class ab che 0.18 12.5 2.1 0.42 11.3 1.0 2.0 1 LRR_EndoS Endo-beta-N-acetylglucosaminidase EndoS LRR do 0.22 11.9 0.2 0.44 11.0 0.2 1.4 1 PRM_STIL Proline-rich motif in STIL 0.93 9.9 7.4 45 4.6 0.1 3.8 3 PetN PetN Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.0 20.9 8.4e-28 2e-24 2 260 .] 277 528 .. 276 528 .. 0.86 Alignments for each domain: == domain 1 score: 87.0 bits; conditional E-value: 8.4e-28 xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 2 NllVilvilrnkklrt.ptnifllnLavaDllvlllvlpfalvyal.legdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykr 95 Nl+V+lv l++k lr+ +t ++ ++a +Dll+++ ++ ++++ ++ + ++ v+ e lC++++++ ++ ++ + + ++i+R+laIv+ ++ ++ FUN_002376-T1 277 NLIVVLVSLTTKVLRRnVTMLLTSSMAASDLLISVYSIILVTARKMpYVEYLVYLEGLCNALGFMWLTGQIVTYKTSLWLTIERFLAIVYCMEPSV 372 9*************998999999************9999999999988899999****************************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 96 irtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkekskk 191 + t+ ra++li+++W+l+l+++++pl +++ +++t C++ p ++ +++++ + lsv g l+ + i+ +y++i+ +rk+++++ +++ FUN_002376-T1 373 RITRGRAVTLIVFTWCLGLAVATLPLAKISVY-----TSNTYCVPIRPIKDIPHSYEMSIALSVWGILV-YFTIIPLYIKIFISVRKTSEQAGKTR 462 ***************************87776.....5689********44335555555555555555.888999******************88 PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF 7tm_1 192 kksarkerkalktllvvvvvfvlcwlPyfilllldsl.lkeceseklvetal.litlllayvnsclNPiiY 260 s a k+ ++v+ v+++lP++i++l+ ++ lk++ s ++ e ++ i +ll +n+ +NP++Y FUN_002376-T1 463 DGS-----VAKKIAILVMSNMVFFFLPVVIAFLWLTTnLKTTMSPQNREILTgVIPTLLFSFNAFINPLLY 528 888.....55677788888888888999999999999533333334444444589999************9 PP >> LRR_8 Leucine rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.8 4.7 8.3e-14 1.9e-10 4 61 .] 63 121 .. 60 121 .. 0.91 2 ! 14.8 2.3 1.1e-05 0.025 3 53 .. 111 160 .. 110 162 .. 0.85 Alignments for each domain: == domain 1 score: 40.8 bits; conditional E-value: 8.3e-14 LRR_8 4 rsLdLssNr.ltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 +sL +s + ++++ g Fk+ +nL+ LdLsnN+++ +++gafs+L L+ LdLs+N+L FUN_002376-T1 63 QSLKISLAKeVETVPNGLFKNFTNLENLDLSNNSIRDIEDGAFSNLIYLQRLDLSSNQL 121 56666666668899*******************************************98 PP == domain 2 score: 14.8 bits; conditional E-value: 1.1e-05 LRR_8 3 LrsLdLssNrltslddgaFkglsnLkvLdLsnNllttlspgafsgLpsLrs 53 L++LdLssN+l + + + l+ L+ L++s+N+ tl p a + L++L++ FUN_002376-T1 111 LQRLDLSSNQLVKWKGNLTNELPRLMFLNISDNTNLTL-PPAVMKLRRLKE 160 899******************************77777.567777777765 PP >> LRR_4 Leucine Rich repeats (2 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 1.2 1.8e-06 0.0043 14 41 .. 74 102 .. 66 107 .. 0.73 2 ! 25.2 6.1 8.1e-09 1.9e-05 1 36 [. 85 121 .. 85 130 .. 0.89 3 ! 13.5 3.7 4e-05 0.092 3 37 .. 111 147 .. 111 151 .. 0.91 4 ? 4.1 0.2 0.036 84 5 28 .. 137 161 .. 133 162 .. 0.76 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 1.8e-06 LRR_4 14 tdidp..lskLpnLetLdLsgNnkitdlsd 41 +++++ +++++nLe LdL +Nn i+d++d FUN_002376-T1 74 ETVPNglFKNFTNLENLDL-SNNSIRDIED 102 5566664667999999999.6669999975 PP == domain 2 score: 25.2 bits; conditional E-value: 8.1e-09 LRR_4 1 pnLetLdLsnNritdidp..lskLpnLetLdLsgNnki 36 +nLe LdLsnN+i di+ +s+L L+ LdLs+N ++ FUN_002376-T1 85 TNLENLDLSNNSIRDIEDgaFSNLIYLQRLDLSSN-QL 121 7*****************99889*********888.55 PP == domain 3 score: 13.5 bits; conditional E-value: 4e-05 LRR_4 3 LetLdLsnNritdidp.lsk.LpnLetLdLsgNnkit 37 L++LdLs+N++ + + l + Lp+L L++s+N+++t FUN_002376-T1 111 LQRLDLSSNQLVKWKGnLTNeLPRLMFLNISDNTNLT 147 89***************9999**********997773 PP == domain 4 score: 4.1 bits; conditional E-value: 0.036 LRR_4 5 tLdLs.nNritdidpls.kLpnLetL 28 L++s n+++t ++p kL +L+++ FUN_002376-T1 137 FLNISdNTNLT-LPPAVmKLRRLKEI 161 79***666***.88855479999987 PP >> LRR_5 BspA type Leucine rich repeat region (6 copies) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.4 4.4e-09 1e-05 15 66 .. 66 119 .. 58 186 .. 0.69 2 ? 1.1 0.0 0.21 5e+02 91 113 .. 174 196 .. 129 210 .. 0.73 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 4.4e-09 LRR_5 15 sitipssltsIgeyaFsnctslksitlps.sltsigsyaFsnc.slesitipss 66 +i++ ++++++ + F+n t+l++++l++ s++ i++ aFsn l++++++s+ FUN_002376-T1 66 KISLAKEVETVPNGLFKNFTNLENLDLSNnSIRDIEDGAFSNLiYLQRLDLSSN 119 455667777777777777777777777552477777777777666777777652 PP == domain 2 score: 1.1 bits; conditional E-value: 0.21 LRR_5 91 tsigssaFsncslksitipssvt 113 + + +++F+n +lk+ +i sv+ FUN_002376-T1 174 KLVRNYTFQNEDLKKHDIDISVS 196 44445555555555555544444 PP >> LRR_1 Leucine Rich Repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.7 4.8e-05 0.11 1 23 [] 86 108 .. 86 108 .. 0.94 2 ! 7.6 0.2 0.0036 8.3 2 13 .. 111 125 .. 110 135 .. 0.73 3 ? 4.1 0.1 0.051 1.2e+02 2 21 .. 135 153 .. 134 155 .. 0.76 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 4.8e-05 LRR_1 1 nLeeLdLsnNnlsgllpeslgnl 23 nLe LdLsnN++ ++ +++nl FUN_002376-T1 86 NLENLDLSNNSIRDIEDGAFSNL 108 8************9999999997 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0036 LRR_1 2 LeeLdLsnNnl...s 13 L++LdLs+N+l FUN_002376-T1 111 LQRLDLSSNQLvkwK 125 9*********95554 PP == domain 3 score: 4.1 bits; conditional E-value: 0.051 LRR_1 2 LeeLdLsnNnlsgllpeslg 21 L L++s+N + +lp+++ FUN_002376-T1 135 LMFLNISDNTNL-TLPPAVM 153 889*******97.6666655 PP >> LRR_14 Leucine-rich repeat region # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.6 1.8e-06 0.0041 44 128 .. 82 170 .. 61 180 .. 0.74 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 1.8e-06 LRR_14 44 gkLlhLRYLgLrntsiseLPee.IgkLqfLqtLdlrgtei.keLPssvvkLrkLmcLrvdegtr..lPdgignLtsLeeLslvsvdsss 128 ++ L L L+n si+++ + +L +Lq Ldl+++++ k + +L +Lm+L ++++t+ lP + +L+ L+e+++v+ ++++ FUN_002376-T1 82 KNFTNLENLDLSNNSIRDIEDGaFSNLIYLQRLDLSSNQLvKWKGNLTNELPRLMFLNISDNTNltLPPAVMKLRRLKEIRGVTWNKHC 170 56667777888888888887651458889999999988883444555558889999999887775568888899999988888875555 PP >> LRR_9 Leucine-rich repeat # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 1.0 1.7e-05 0.039 44 101 .. 87 147 .. 71 179 .. 0.82 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 1.7e-05 LRR_9 44 fdtidlsdneirkldg..fPllkrlktlllnnnrilrigegleevlPnleeliltkns.lq 101 ++ +dls+n ir++++ f l l+ l l +n++++ +l + lP+l l +++n+ l+ FUN_002376-T1 87 LENLDLSNNSIRDIEDgaFSNLIYLQRLDLSSNQLVKWKGNLTNELPRLMFLNISDNTnLT 147 6789*********985448889999*************************99998886343 PP >> 7TM_GPCR_Srab Serpentine type 7TM GPCR receptor class ab chemoreceptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 5.5 2.5e-05 0.058 96 195 .. 335 436 .. 333 515 .. 0.70 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2.5e-05 7TM_GPCR_Srab 96 CfvlRllYnfGlflvsvttvsLviERliAtvrsskYenksk.llGillailqlllallllvllysetkfegavmyYCttlkss..spesleipelv 188 C l +++ +G++++ t++ L+iER++A+v+ ++ + + + l+++ +l+l++ +l +++ + YC+ +++ +p s e+++++ FUN_002376-T1 335 CNALGFMWLTGQIVTYKTSLWLTIERFLAIVYCMEPSVRITrGRAVTLIVFTWCLGLAVATLPLAKISV-YTSNTYCVPIRPIkdIPHSYEMSIAL 429 777889**************************998765533134599*********************9.9999****998764455555555555 PP 7TM_GPCR_Srab 189 iivsqiv 195 ++ +v FUN_002376-T1 430 SVWGILV 436 4443333 PP >> LRR_EndoS Endo-beta-N-acetylglucosaminidase EndoS LRR domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 1.0 0.00018 0.42 77 116 .] 80 119 .. 32 119 .. 0.80 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00018 LRR_EndoS 77 elkgltaLktldlsglkleklealdveslksLkkvDiSeN 116 k++t L++ldls+ + ++e+ +++l L+++D+S N FUN_002376-T1 80 LFKNFTNLENLDLSNNSIRDIEDGAFSNLIYLQRLDLSSN 119 4799**********************************98 PP >> PRM_STIL Proline-rich motif in STIL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.2 0.00019 0.44 19 34 .. 572 587 .. 551 591 .. 0.88 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.00019 PRM_STIL 19 edlsPRpsPsPHpvsq 34 ++l PRp P PH v+ FUN_002376-T1 572 GSLAPRPLPKPHRVGS 587 689*********9975 PP >> PetN PetN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.1 0.019 45 13 22 .. 266 275 .. 264 276 .. 0.89 2 ? 3.5 0.5 0.04 93 5 22 .. 375 392 .. 374 399 .. 0.84 3 ? 3.6 0.1 0.037 87 17 25 .. 425 433 .. 423 433 .. 0.92 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.019 PetN 13 avFtfSiAlV 22 + Ft++iAlV FUN_002376-T1 266 VYFTSPIALV 275 68*******9 PP == domain 2 score: 3.5 bits; conditional E-value: 0.04 PetN 5 tlGWaAllavFtfSiAlV 22 t G+a l vFt+ + l FUN_002376-T1 375 TRGRAVTLIVFTWCLGLA 392 779999999***998775 PP == domain 3 score: 3.6 bits; conditional E-value: 0.037 PetN 17 fSiAlVVWG 25 +SiAl VWG FUN_002376-T1 425 MSIALSVWG 433 6*******9 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (598 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1084 (0.0424349); expected 510.9 (0.02) Passed bias filter: 520 (0.0203562); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 12 (0.000469759); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 5770.08 // Query: FUN_002377-T1 [L=435] Description: FUN_002377 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-57 196.1 15.3 1.1e-55 189.8 15.3 2.0 1 CLN3 CLN3 protein 2.7e-06 27.0 20.1 4.4e-06 26.3 19.1 1.8 1 MFS_1 Major Facilitator Superfamily Domain annotation for each model (and alignments): >> CLN3 CLN3 protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 189.8 15.3 8.9e-60 1.1e-55 2 392 .. 34 403 .. 33 405 .. 0.91 Alignments for each domain: == domain 1 score: 189.8 bits; conditional E-value: 8.9e-60 CLN3 2 afwllGLiNNvlYvviLsAAlDlv.gksvpkgvvlladilPsllikllapffihkvpysvRvlllvllsalgmllvalskslavkllGvvlaslss 96 f+++G + ++L AA D++ gk++p++++l+a + P +++k+++p+++++v+y+v++++++l ++g++lv +++ vkllG++l ++++ FUN_002377-T1 34 CFYIFGTTTFFNQEMLLPAAEDILsGKRLPTATILVAIVAPLMITKMTVPWLVERVSYAVKICAIALSMTTGLVLVGAFEDIRVKLLGIALNAVAT 129 69**********************66889******************************************************************* PP CLN3 97 GlGEvtfLqlthfyekeslaawssGTGgAGlvGallyalltellglsvkttlllslvlPlllllsyflllpkekleksakaeeeyealeeeeeeee 192 G+ Ev fL+l++fy++ +++a+ +GTG+A l+ y+ lt++ +s+kt++l+++ lP+l +l ++++l+ke++++s+ +y+++++++e FUN_002377-T1 130 GAAEVVFLALSSFYSDICISAYVAGTGMASLFSPAYYTGLTTWSCVSPKTAILITTPLPFLSVL-FYTMLDKERAKESE---IKYTRVDSTTEA-- 219 *************************************************************999.66666665443333...334444332211.. PP CLN3 193 eeaeeeelleseaasaeeeeeeeeekslkeslkeklkrlksLllkymlPLllVYlaeYliNqgvaptllfpleekpfkslrdqYrvyqvlYqlgvf 288 ++ + k s++ekl+ + ++ ++++ L+l +++eYl +v+ t+ fp +lrd + +y + Y +g f FUN_002377-T1 220 ----------------------GSDVQKKFSCSEKLRIALKI-SPFIIALCLSFFSEYLSMSSVVTTIAFPR---SGIDLRDHFIYYTLSYGVGKF 289 ......................11223345688999999998.9***************************8...5789***************** PP CLN3 289 isRssvsllri...........rklyllsvlQvlnlvllllealfelllpsiylvfllifyeGllGGaaYvntfaeiseevekeerefslgavsvs 373 i Rs + ll++ ++ ++ +vl ++ lv+llle++f++ +p i++++ll Gll G+ v+ ++ ++v++eeref+lg +++ FUN_002377-T1 290 IGRSHLFLLSFlplddieflkcSRTWIFTVLETAHLVFLLLESCFHF-VPFIWIIILLCSSIGLLAGMIVVHSPHAAGRRVTPEEREFALGLLTIG 384 *****9988888889999999999*********************77.************************************************ PP CLN3 374 dslGillagllalplekal 392 + +G +lagl++l +e+ l FUN_002377-T1 385 NGVGSFLAGLAGLIVEPFL 403 ***************9876 PP >> MFS_1 Major Facilitator Superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 19.1 3.4e-10 4.4e-06 8 346 .. 42 392 .. 32 393 .. 0.69 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 3.4e-10 MFS_1 8 aalgrsllgpalplllaedlgispseigllltlfslgyalaqllaGrlsdrfGrrrvlllglllfalg..lllllfasslwlllvlrvlqGlgaga 101 +++++ +l pa + l + +l++ + ++ + + +l++r++ v +++++l+ + +l+++f + + l++ +l+++++ga FUN_002377-T1 42 TFFNQEMLLPAAE-DI---LSGKRLPTATILVAIVAPLMITKMTVPWLVERVS-YAVKICAIALSMTTglVLVGAF-EDIRVKLLGIALNAVATGA 131 4555555555555.33...44444445556666677889999999******94.4444444444444421244447.89889999********999 PP MFS_1 102 lfpaaaaliadwfpkeergralgllsagfglGaalGpllggllaslfg...wravFlilailallaavlaalllprpppeskrkkpaee....... 187 + ++ al + ++ ++ + ag+g+++++ p+ + l++ ++ +++ li+ +l +l++++ + ++++++ ++ + + + FUN_002377-T1 132 AEVVFLALSSFYSDI-----CISAYVAGTGMASLFSPAYYTGLTT-WScvsPKTAILITTPLPFLSVLF--YTMLDKERAKESEIKYTRvdsttea 219 999999999998887.....9***************988888884.4446699*************775..4445555555555555556799998 PP MFS_1 188 .....apapllpawkallrdpvlwlllalllfglaffalltllply.qevlgls...glllaglllglaallgaigrlllgrls.dr...lgrrrr 270 +++++++ ++++l+ ++ +++++l+f+ + ++++ + ++ + g++ +++ l +g++ ++g +ll+ l d l+ r+ FUN_002377-T1 220 gsdvqKKFSCSEKLRIALKISPF-IIALCLSFFSEYLSMSSVVTTIaFPRSGIDlrdHFIYYTLSYGVGKFIGRSHLFLLSFLPlDDiefLKCSRT 314 88888777777788888887777.777777777777778888888888888888778445555558888888855566666666555676555555 PP MFS_1 271 lllallllllaalgllllslt.esslwlll.alll..lGfgfglvfplllalvsdlapkeergtasglyntagslggalg 346 +++++l ++ ++++ll + + +w+++ + + +G+ +g++++ + + +++ +eer +a+gl ++++++g++l+ FUN_002377-T1 315 WIFTVLETAHLVFLLLESCFHfVPFIWIIIlL--CssIGLLAGMIVVHSPHAAGRRVTPEEREFALGLLTIGNGVGSFLA 392 55554444433333333322212223333324..256*****************************************97 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (435 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 639 (0.0250147); expected 510.9 (0.02) Passed bias filter: 329 (0.0128792); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.39s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 4366.46 // Query: FUN_002378-T1 [L=540] Description: FUN_002378 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-35 123.3 0.0 5.6e-35 121.3 0.0 1.9 1 CERK_C Ceramide kinase C-terminal domain 5.3e-26 91.2 0.0 8.9e-26 90.4 0.0 1.4 1 DAGK_cat Diacylglycerol kinase catalytic domain 3.4e-14 53.6 0.1 7.7e-14 52.5 0.1 1.6 1 PH_CERK Ceramide kinase PH domain 6.8e-05 23.1 0.0 0.0002 21.5 0.0 1.8 1 YegS_C YegS C-terminal NAD kinase beta sandwich-like ------ inclusion threshold ------ 0.24 11.5 0.0 0.38 10.9 0.0 1.2 1 Peptidase_S51 Peptidase family S51 Domain annotation for each model (and alignments): >> CERK_C Ceramide kinase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 121.3 0.0 1.1e-38 5.6e-35 3 218 .. 285 534 .. 283 538 .. 0.86 Alignments for each domain: == domain 1 score: 121.3 bits; conditional E-value: 1.1e-38 CERK_C 3 amfGfGgrtlalaekkrWmspsqrrefaviktlaklkpedcelsflplkssqdeeekkaq..................eskksdaeeqWqtiqGlf 80 a +Gf g + +ek rWm p +r + a k + + + + +s+lp+++ ++ + + + s+++++ ++Wq+++G+f FUN_002378-T1 285 AAYGFFGDVMQDSEKLRWMGP-KRYDVAGFKKFMTNRGYEGVVSYLPVETLDTSPQDSLRcrsgcnickssfntvhqrPSQQNSSASSWQSMRGRF 379 88*****************99.689**********************98766644444445678999999999998765667777899******** PP CERK_C 81 lnvsimaiPclcsvaPrGlaPntrlnngsmalivvrntsrsefikhlkryasvknqfnfpfvetytveevkvrprsksslsdeeee.......... 166 ++v i c c+ +P Gl+P ++l +g +li v++tsr ++++h+ r +s+ qfnf fve + v+e rp + s +e++ FUN_002378-T1 380 ISVIGANISCACAKSPEGLSPSAHLADGCLDLILVKHTSRLQYLRHMLRITSKADQFNFDFVEVHRVSEFSFRPLGEESEPVDEADgreksgtkeg 475 ***************************************************************************999998888888999999999 PP CERK_C 167 ....ketkaiasekt....ypWnidGdllevasevlirvhprlitlyGesveeledskvk 218 k+++s Wn+dG+l+ + ++vh++li+l+ + +ee ed+ FUN_002378-T1 476 dkeyLAGKITSSPPRlgprSVWNVDGELITH-PAIDVKVHRQLIRLFARGIEECEDTPSC 534 877633445555433112257********95.569*********************9644 PP >> DAGK_cat Diacylglycerol kinase catalytic domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 90.4 0.0 1.7e-29 8.9e-26 1 124 [. 129 270 .. 129 271 .. 0.92 Alignments for each domain: == domain 1 score: 90.4 bits; conditional E-value: 1.7e-29 DAGK_cat 1 kllvivNpksGkgkgkkll.kkveellekagvelelveteeagdakelareaaekgvdlvvvvGGDGtvnevlnglaelatk.............. 81 +llv++Np +G++ g+k++ ++v++l+e a+++++++ t++a++a++++ e ++vd+vv vGGDG+++evlngl+ +a++ FUN_002378-T1 129 RLLVFINPVGGRRLGHKIYvEQVQPLFELANIKVDMIVTQKANHARDYLMEEGLEKVDGVVSVGGDGMFHEVLNGLLMRAQQeamlnsssqdfqpv 224 689*********************************************9999999**********************9444456677777778888 PP DAGK_cat 82 ...pplgiiPlGtgNdfaralglpkdpeealeallkgetrkvdvgk 124 +p+giiP+G+++++a + ++dp + + +++ g+ +++dv+ FUN_002378-T1 225 plnIPIGIIPAGSTDAIAFCTTGNNDPVTSALHIILGDRQPLDVCC 270 888******************9999******************986 PP >> PH_CERK Ceramide kinase PH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.5 0.1 1.5e-17 7.7e-14 3 113 .] 10 117 .. 8 117 .. 0.87 Alignments for each domain: == domain 1 score: 52.5 bits; conditional E-value: 1.5e-17 PH_CERK 3 seLllkqrrvevsLsralLaWkelepekkrasgeseaakshsVpvsEIia.VeeteeeekkkksgkwqkmakpshaftVsyvkrarqhrWrcsevt 97 s+L ++ ++++v+L++ L+W ++ e + +++ + + s p+ E++a V + + e+++++g ++ +f ++ vkr+r+h+Wr + + FUN_002378-T1 10 SVLYVEGKSFDVVLTQNSLSWGHVGIEDYK---QVNPSFKKSLPLHEVFAaVPYQAKLEQSTEEGIELAFLRR-LSFCIYSVKRTRKHKWREKMIV 101 899*******************97666655...3467899********9736666666777888888888888.********************** PP PH_CERK 98 FwcadeqlceqWiqal 113 F c d lce+W++a+ FUN_002378-T1 102 FDCDDAVLCEEWLHAI 117 *************986 PP >> YegS_C YegS C-terminal NAD kinase beta sandwich-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 4e-08 0.0002 73 139 .. 398 468 .. 375 478 .. 0.84 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 4e-08 YegS_C 73 iaPdArvdDGlLDvvvieaasraellrllpkvy.dGkhvrlpevevlrgreveie...asr.llpvgaDGEe 139 ++P+A+++DG LD+++++++sr++ lr + ++ + + + + vev r +e + + + + + + +aDG e FUN_002378-T1 398 LSPSAHLADGCLDLILVKHTSRLQYLRHMLRITsKADQFNFDFVEVHRVSEFSFRplgE-EsEPVDEADGRE 468 68*************************98887615678899999999999999987743.347788899855 PP >> Peptidase_S51 Peptidase family S51 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.9 0.0 7.4e-05 0.38 17 93 .. 115 195 .. 108 219 .. 0.81 Alignments for each domain: == domain 1 score: 10.9 bits; conditional E-value: 7.4e-05 Peptidase_S51 17 hldkalldflgksekkvlFi.PtAsvsedsdeyvekvrkaleklglevdelhlskdpeae...ieeklleadviyvgGGnt 93 h+ +++l+ +++ ++ ++Fi P ++ ++ yve+v+ ++e +++vd + ++k+++a+ +ee l+++d+++ GG+ FUN_002378-T1 115 HAIQTVLSGFNRPKRLLVFInPVGGRRLGHKIYVEQVQPLFELANIKVDMIVTQKANHARdylMEEGLEKVDGVVSVGGDG 195 33444444444446677888899999999***********************99999998898999*******99999875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (540 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 795 (0.0311216); expected 510.9 (0.02) Passed bias filter: 645 (0.0252496); expected 510.9 (0.02) Passed Vit filter: 53 (0.00207477); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.37u 0.39s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 5198.10 // Query: FUN_002379-T1 [L=491] Description: FUN_002379 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-66 223.2 0.0 7e-66 222.8 0.0 1.2 1 Pkinase Protein kinase domain 5.6e-34 118.1 0.0 8.2e-34 117.5 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.00011 21.9 0.1 0.00036 20.2 0.1 1.8 1 Haspin_kinase Haspin like kinase domain 0.00092 19.0 0.0 0.0015 18.3 0.0 1.4 1 Kinase-like Kinase-like 0.0012 18.6 0.0 0.0032 17.1 0.0 1.6 2 ABC1 ABC1 atypical kinase-like domain ------ inclusion threshold ------ 0.018 15.0 0.1 0.05 13.5 0.1 1.6 1 Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 0.065 12.7 0.1 0.11 12.0 0.1 1.3 1 Seadorna_VP7 Seadornavirus VP7 Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 222.8 0.0 1.9e-69 7e-66 1 262 [] 160 441 .. 160 441 .. 0.89 Alignments for each domain: == domain 1 score: 222.8 bits; conditional E-value: 1.9e-69 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdlls.rkgal 95 y +l+klGeG++++V+k+++k t+++vA+K+i+ e+++ +++rE+++lk lkh niv+l+d+++++++l+lv+Ey+e++ l++++ g++ FUN_002379-T1 160 YIKLDKLGEGTYATVFKGKSKLTDNLVALKEIRLEHEEGAPC-TAIREVSLLKDLKHANIVTLHDIVHTPKSLTLVFEYLEKD-LKQYMDdCGGIM 253 66789******************************9998776.9*************************************66.99999945566* PP Pkinase 96 seeeakkilkqilegleylHsegvvHrDlKpeNiLidekgelKitDFGlakelesssk.ltsfvgtseYmAPEvl.kskkygkkvDvWslGvilye 189 s ++++ +l q+l+gl+y+H+++v+HrDlKp+N+Li++kgelK++DFGla+ + +k +++ v+t +Y++P vl +s++y++++D+W++G+i++e FUN_002379-T1 254 SMNNVRLFLFQLLRGLHYCHNRKVLHRDLKPQNLLINDKGELKLADFGLARAKSVPTKtYSNEVVTLWYRPPDVLlGSTEYSTQIDMWGVGCIFFE 349 **************************************************988777666****************9******************** PP Pkinase 190 lltgkppfsaekekekvekeldqlekilki...elkeklpepssi.......................seeakdllkkllkkdpkkRltaeellqh 259 + tg+p f++++ ++ ql+ i+k+ +++e++p + +++ +ll++ ++ k+R++a ++++h FUN_002379-T1 350 MATGRPFFPGSTVED-------QLHLIFKTlgtPTEESWPGITANevfvsgrfphysrehlvnhaprlDNSGLNLLERFVEFVVKDRISAIDAMKH 438 *********555555.......4444444433355666665444466888889999999999999999**************************** PP Pkinase 260 pwf 262 ++f FUN_002379-T1 439 EYF 441 **8 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 117.5 0.0 2.3e-37 8.2e-34 5 221 .. 164 373 .. 161 389 .. 0.90 Alignments for each domain: == domain 1 score: 117.5 bits; conditional E-value: 2.3e-37 PK_Tyr_Ser-Thr 5 eklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkkkekl 99 +klGeG++++V+kg+ k ++ Va+K ++ e++e + ++e++l+k+l+h niv+l+ ++ ++l +v+ey+e+ +Lk+++ + + FUN_002379-T1 164 DKLGEGTYATVFKGKSK----LTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTPKSLTLVFEYLEK-DLKQYMDDCGGIM 253 69***************....9999******************************************************98.9************ PP PK_Tyr_Ser-Thr 100 slkellklalqiAkGmeyLeskklvHrdlaarNvLvsekkvvkisDfGLardvekddyykkkekaklpikWmapEslkekk.ftsksDvWsfGvl 193 s++++ + q+ +G++y +++k++Hrdl +N L+++k k++DfGLar+ + +k+ +++ + + + +p +l ++ ++++ D+W G + FUN_002379-T1 254 SMNNVRLFLFQLLRGLHYCHNRKVLHRDLKPQNLLINDKGELKLADFGLARAK--SVPTKTYSNEVVTLWYRPPDVLLGSTeYSTQIDMWGVGCI 346 ****************************************************9..334444555666666679999876555************* PP PK_Tyr_Ser-Thr 194 lwEiftlgeepykglkneevlelleege 221 +E++t g+ ++g + e+ l+l+ + FUN_002379-T1 347 FFEMAT-GRPFFPGSTVEDQLHLIFKTL 373 *****9.999899998888888776655 PP >> Haspin_kinase Haspin like kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.1 9.8e-08 0.00036 179 260 .. 225 316 .. 85 338 .. 0.83 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 9.8e-08 Haspin_kinase 179 denqlflvlllkkkGkdLehv.....klkswaqalsifwqivkilyvaEtkfqFEHRdLhldniLvdknlnvtlidyklaRak......ssng 260 ++ ++l l++++ kdL++ + s++++ ++q + l + + HRdL+ +n+L++ ++++ l d+ laRak +sn+ FUN_002379-T1 225 VHTPKSLTLVFEYLEKDLKQYmddcgGIMSMNNVRLFLFQLLRGLHYCHNR-KVLHRDLKPQNLLINDKGELKLADFGLARAKsvptktYSNE 316 4556788999999999999987777789*****************998877.677***************************96555543333 PP >> Kinase-like Kinase-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 4.2e-07 0.0015 152 245 .. 263 351 .. 214 367 .. 0.82 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 4.2e-07 Kinase-like 152 lqlirlaasLqskglvhgkfsvdnllldekggvflggfeaLvrag...tkvv.seve.kgfaPpEllgsrgglytrknktlmtfkldaWqlGlvIy 242 ql+r + ++ ++h +++++nll++ kg ++l +f+ L ra+ tk+ +ev + Pp++l t+ + ++d W++G + FUN_002379-T1 263 FQLLRGLHYCHNRKVLHRDLKPQNLLINDKGELKLADFG-LARAKsvpTKTYsNEVVtLWYRPPDVLLG---------STEYSTQIDMWGVGCIFF 348 5899999999****************************8.6776623334443554436799**99765.........4778889*******9999 PP Kinase-like 243 siw 245 ++ FUN_002379-T1 349 EMA 351 887 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.0 1.3 4.9e+03 34 61 .. 164 190 .. 146 194 .. 0.73 2 ! 17.1 0.0 8.9e-07 0.0032 185 224 .. 273 312 .. 251 323 .. 0.80 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 1.3 ABC1 34 deePiAaASiaqVhkArlk.dgeeVavKv 61 d+ ++ a+V+k++ k + + Va+K FUN_002379-T1 164 DK--LGEGTYATVFKGKSKlTDNLVALKE 190 54..5666679999999998888999995 PP == domain 2 score: 17.1 bits; conditional E-value: 8.9e-07 ABC1 185 fedgffhaDphpGNllvrkdgelvllDfGlmgeldekfrk 224 + +++h D+ p Nll++++gel l DfGl + + ++ FUN_002379-T1 273 HNRKVLHRDLKPQNLLINDKGELKLADFGLARAKSVPTKT 312 46789*************************9876655554 PP >> Kdo Lipopolysaccharide kinase (Kdo/WaaP) family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.1 1.4e-05 0.05 57 180 .. 202 314 .. 192 323 .. 0.87 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.4e-05 Kdo 57 rafrEfrllkrleeagvavpkpvaagikkvgleyrAlllteklegaqdLedllaqwae.laeelrrallkavgrlirklhragvqHgdlyakhill 151 +a rE++llk l++a + ++ + k l+ e le +dL++++ + ++ + r l ++ r + h+++v H+dl ++++l+ FUN_002379-T1 202 TAIREVSLLKDLKHANIVTLHDIVHTPKSL------TLVFEYLE--KDLKQYMDDCGGiMSMNNVRLFLFQLLRGLHYCHNRKVLHRDLKPQNLLI 289 889999999999999999999998776654......68999999..59****999877999999999999************************** PP Kdo 152 qtekeeeakasliDldkarlrlrakrwre 180 + ++ ++ l D+ ar ++ +++ + FUN_002379-T1 290 NDKG----ELKLADFGLARAKSVPTKTYS 314 *999....99999*999999998887655 PP >> Seadorna_VP7 Seadornavirus VP7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.1 3e-05 0.11 139 189 .. 252 302 .. 245 319 .. 0.67 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 3e-05 Seadorna_VP7 139 ikvltvniivaG.lksLmdlhr.esggtlhGDvnvenlmcDklGmlklvDPas 189 i+ + n + ++ L lh + ++lh D +++nl+ + G lkl D + FUN_002379-T1 252 IMSM--NNVRLFlFQLLRGLHYcHNRKVLHRDLKPQNLLINDKGELKLADFGL 302 4443..3332220333444554136789*********************9765 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (491 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 538 (0.0210609); expected 510.9 (0.02) Passed bias filter: 511 (0.0200039); expected 510.9 (0.02) Passed Vit filter: 33 (0.00129184); expected 25.5 (0.001) Passed Fwd filter: 7 (0.000274026); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.36u 0.37s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 4867.65 // Query: FUN_002380-T1 [L=102] Description: FUN_002380 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (102 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 505 (0.019769); expected 510.9 (0.02) Passed bias filter: 428 (0.0167547); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.41s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1065.16 // Query: FUN_002381-T1 [L=196] Description: FUN_002381 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-06 27.5 0.3 3e-06 27.5 0.3 2.1 2 PAN_1 PAN domain ------ inclusion threshold ------ 0.015 16.3 7.6 0.015 16.3 7.6 2.6 2 ShK ShK domain-like 0.02 15.5 0.6 0.02 15.5 0.6 2.4 2 PAN_2 PAN-like domain Domain annotation for each model (and alignments): >> PAN_1 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.9 1.4 0.5 4.2e+03 24 31 .. 50 57 .. 25 75 .. 0.70 2 ! 27.5 0.3 3.5e-10 3e-06 6 58 .. 100 156 .. 96 169 .. 0.92 Alignments for each domain: == domain 1 score: -1.9 bits; conditional E-value: 0.5 PAN_1 24 aeeCaqrC 31 ae+C + C FUN_002381-T1 50 AEYCKRSC 57 34444444 PP == domain 2 score: 27.5 bits; conditional E-value: 3.5e-10 PAN_1 6 vpgsslegedkktvtvssaeeCaqrCaeekrCrsftYnek....skkCllksessgs 58 v++++l+g+ ++t tv s+ +C C+ ++C +++Yn + kkC+l ++ +++ FUN_002381-T1 100 VKDKVLQGHVIWTQTVLSELQCEDYCLRLPSCLAYNYNCSrgvgPKKCELLNSVTDT 156 78899***********************************99999*****9998877 PP >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.3 7.6 1.8e-06 0.015 2 37 .] 27 60 .. 26 60 .. 0.94 2 ? -0.0 2.6 0.23 2e+03 1 18 [. 120 139 .. 120 148 .. 0.80 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 1.8e-06 ShK 2 CvDps.sdCaswaang.CnspayqdfmkenCpktCgfC 37 C D+s + C+ + + + C+ +++ +e+C+++C++C FUN_002381-T1 27 CSDTSiVACWIIEKANvCQ----ESYAAEYCKRSCNYC 60 9999999***********6....69************* PP == domain 2 score: -0.0 bits; conditional E-value: 0.23 ShK 1 sCvDps...sdCaswaangCn 18 +C+D+ ++C ++ n C+ FUN_002381-T1 120 QCEDYClrlPSCLAYNYN-CS 139 58876666699*999999.97 PP >> PAN_2 PAN-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 2.5 0.52 4.4e+03 26 37 .. 46 57 .. 22 71 .. 0.74 2 ? 15.5 0.6 2.4e-06 0.02 28 57 .. 116 147 .. 104 152 .. 0.79 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.52 PAN_2 26 ksitlkeCeerC 37 +s ++ C+++C FUN_002381-T1 46 ESYAAEYCKRSC 57 336666677776 PP == domain 2 score: 15.5 bits; conditional E-value: 2.4e-06 PAN_2 28 itlkeCeerClsnCsCtAYayadir..ggkgC 57 ++ +Ce+ Cl+ sC AY y+ r g k+C FUN_002381-T1 116 LSELQCEDYCLRLPSCLAYNYNCSRgvGPKKC 147 56679****************86666444888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (196 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 710 (0.0277941); expected 510.9 (0.02) Passed bias filter: 315 (0.0123312); expected 510.9 (0.02) Passed Vit filter: 23 (0.000900372); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 2026.70 // Query: FUN_002381-T2 [L=201] Description: FUN_002381 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-06 27.4 0.3 3.1e-06 27.4 0.3 2.0 2 PAN_1 PAN domain ------ inclusion threshold ------ 0.016 16.2 7.6 0.016 16.2 7.6 2.7 2 ShK ShK domain-like 0.023 15.3 0.7 0.023 15.3 0.7 2.4 2 PAN_2 PAN-like domain Domain annotation for each model (and alignments): >> PAN_1 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 2.4 1.4 1.2e+04 24 31 .. 53 60 .. 28 67 .. 0.68 2 ! 27.4 0.3 3.7e-10 3.1e-06 6 58 .. 105 161 .. 101 174 .. 0.92 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 1.4 PAN_1 24 aeeCaqrC 31 ae+C + C FUN_002381-T2 53 AEYCKRSC 60 44555554 PP == domain 2 score: 27.4 bits; conditional E-value: 3.7e-10 PAN_1 6 vpgsslegedkktvtvssaeeCaqrCaeekrCrsftYnek....skkCllksessgs 58 v++++l+g+ ++t tv s+ +C C+ ++C +++Yn + kkC+l ++ +++ FUN_002381-T2 105 VKDKVLQGHVIWTQTVLSELQCEDYCLRLPSCLAYNYNCSrgvgPKKCELLNSVTDT 161 78899***********************************99999*****9998877 PP >> ShK ShK domain-like # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.2 7.6 1.9e-06 0.016 2 37 .] 30 63 .. 29 63 .. 0.94 2 ? -0.1 2.6 0.24 2e+03 1 18 [. 125 144 .. 125 153 .. 0.80 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.9e-06 ShK 2 CvDps.sdCaswaang.CnspayqdfmkenCpktCgfC 37 C D+s + C+ + + + C+ +++ +e+C+++C++C FUN_002381-T2 30 CSDTSiVACWIIEKANvCQ----ESYAAEYCKRSCNYC 63 9999999***********6....69************* PP == domain 2 score: -0.1 bits; conditional E-value: 0.24 ShK 1 sCvDps...sdCaswaangCn 18 +C+D+ ++C ++ n C+ FUN_002381-T2 125 QCEDYClrlPSCLAYNYN-CS 144 58876666699*999999.97 PP >> PAN_2 PAN-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 2.8 0.75 6.4e+03 25 37 .. 48 60 .. 25 68 .. 0.74 2 ? 15.3 0.7 2.7e-06 0.023 28 57 .. 121 152 .. 110 157 .. 0.79 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.75 PAN_2 25 dksitlkeCeerC 37 ++s ++ C+++C FUN_002381-T2 48 QESYAAEYCKRSC 60 3346667777777 PP == domain 2 score: 15.3 bits; conditional E-value: 2.7e-06 PAN_2 28 itlkeCeerClsnCsCtAYayadir..ggkgC 57 ++ +Ce+ Cl+ sC AY y+ r g k+C FUN_002381-T2 121 LSELQCEDYCLRLPSCLAYNYNCSRgvGPKKC 152 56679****************86666444888 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (201 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 722 (0.0282638); expected 510.9 (0.02) Passed bias filter: 330 (0.0129184); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.34s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 2071.00 // Query: FUN_002382-T1 [L=417] Description: FUN_002382 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.9e-15 55.8 0.1 1.2e-14 55.1 0.1 1.3 1 Abhydrolase_1 alpha/beta hydrolase fold 2.6e-08 34.0 0.0 6.2e-08 32.7 0.0 1.6 1 Hydrolase_4 Serine aminopeptidase, S33 4.4e-05 24.7 0.0 6.3e-05 24.2 0.0 1.2 1 Abhydrolase_6 Alpha/beta hydrolase family 0.0033 17.3 0.0 0.0083 16.0 0.0 1.6 1 DUF915 Alpha/beta hydrolase of unknown function (DU ------ inclusion threshold ------ 0.013 15.7 0.0 0.028 14.6 0.0 1.7 1 Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family) 0.014 14.6 0.0 0.019 14.2 0.0 1.4 1 Ndr Ndr family 0.019 14.9 0.1 0.9 9.5 0.0 2.3 2 Peptidase_S9 Prolyl oligopeptidase family 0.024 15.0 0.0 0.08 13.3 0.0 1.7 1 VirJ Bacterial virulence protein (VirJ) 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 ANTH ANTH domain 0.18 12.0 0.0 30 4.9 0.0 2.4 2 N_formyltrans_C N-formyltransferase dimerization C-terminal Domain annotation for each model (and alignments): >> Abhydrolase_1 alpha/beta hydrolase fold # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.1 0.1 4.5e-18 1.2e-14 2 244 .. 118 372 .. 118 373 .. 0.87 Alignments for each domain: == domain 1 score: 55.1 bits; conditional E-value: 4.5e-18 Abhydrolase_1 2 pvlllHGlpgssdlwrk..lapaLakdgfrvialDlrGfGkSsrpkaq...ddyrtddlaedlekildalglekvnlvGhSlGGlialayaaky.. 90 ++++++G++++s+ ++ +a++ +gfrv +l+++G k + +++ + t++l +++ + +l++++++ vG+S+G++i + y+ + FUN_002382-T1 118 TIVIVPGIANCSETQYVrtFADYAMNQGFRVAVLNHLGAKKKEGLSTPrlfTYGGTEELDAVVTHLTSKLNHKRLVGVGFSMGANILMKYLGEIps 213 59************9999977777777********************99965559999************************************99 PP Abhydrolase_1 91 .pervkalvllga...lspaaeldeaarfilasfpgffdgfvadfarnrlgrlvakelallllrlrllkalpelskrfpsedlalakslvtgallf 182 +e + + ++++ + a + + + + ++ + + +++ + + +l++ + +++ + + + +++ s+ + +d+++ k+ +l FUN_002382-T1 214 rQEYFECGISVCQgydILRAKTFLDQWNGLRRLYNWGMTQNMKKIIDRHVRVLFEGPNFTSHRHKASIHHVRSSSSLAELDDVYTKKMAGFHHLDD 309 9999**************************************************999999998877766656655555556655555555555555 PP Abhydrolase_1 183 letwstelrakllgrldeptlviwgeqDplvppqaleklaqlfpn...arevvipdagHfafleg 244 + s +++ ++++ ++p+l++++ +Dplvp++ + ++ ++ a +v+ ++gH+ f+eg FUN_002382-T1 310 FYARSSCCN--YINQVQIPVLLLNSLDDPLVPEELYVTPHNHVKSnesAIFVITRHGGHLGFFEG 372 544444444..8999999***************999999999444467***************97 PP >> Hydrolase_4 Serine aminopeptidase, S33 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.7 0.0 2.4e-11 6.2e-08 3 225 .. 115 359 .. 113 372 .. 0.76 Alignments for each domain: == domain 1 score: 32.7 bits; conditional E-value: 2.4e-11 Hydrolase_4 3 pkavvvlvHGlgehsg.ryae.laeaLaaqGfavyalDhrGhGksegkrghvpsfddy..vdDlaafvekikeehpglplfllGhSmGGaiallyl 94 k ++v+v G++ s+ +y + +a++ +qGf v l+h G k eg p++ +y + l+a+v++++++ ++++l+ +G SmG+ i ++yl FUN_002382-T1 115 EKLTIVIVPGIANCSEtQYVRtFADYAMNQGFRVAVLNHLGAKKKEGLST--PRLFTYggTEELDAVVTHLTSKLNHKRLVGVGFSMGANILMKYL 208 57799*****998775246555***********************99999..5555554489********************************** PP Hydrolase_4 95 leypd...kvkglilsaPalkikekv........appllkl.lakllskllpklrv............snkldpdslsrdpevvkayaaDplvhgk 166 e p+ ++ i ++ ++i +++l ++ + + ++k++ +++ s+ + + + D+ +++k FUN_002382-T1 209 GEIPSrqeYFECGISVCQGYDILRAKtfldqwngLRRLYNWgMTQNMKKII----DrhvrvlfegpnfTSHRHKASIHHVRSSSSLAELDDVYTKK 300 555543335666677776666654435655533322222223223333322....2334567788888899999999999999999999****999 PP Hydrolase_4 167 isvrlllellragerlekraekitvPllllhGgaDkvvdpagsrelyeragskdktlkl 225 + l+ + a + + + +++++P+lll + +D++v+++ +++++s++ + + FUN_002382-T1 301 MAGFHHLDDFYARSSCCNYINQVQIPVLLLNSLDDPLVPEELYVTPHNHVKSNESAIFV 359 99888888899999999**********************99998888888887555544 PP >> Abhydrolase_6 Alpha/beta hydrolase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 2.4e-08 6.3e-05 23 208 .. 141 370 .. 119 377 .. 0.58 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 2.4e-08 Abhydrolase_6 23 llaagvrvlapDlpGh....Gssdpppldladvadladlldelga..gggpvvlvGHSlGGavalaaa..lvag..vllap.pvaplgllaallal 107 + ++g+rv ++ +G G s+p+ ++++ ++l++++++l +++ v vG+S+G+ + + ++ + ++ + ++ +v++ ++ ++ + FUN_002382-T1 141 AMNQGFRVAVLNHLGAkkkeGLSTPRLFTYGGTEELDAVVTHLTSklNHKRLVGVGFSMGANILMKYLgeIPSRqeYFECGiSVCQGYDILRAKTF 236 335557667766666666667899999*****9999*******999888889**************777733444566666333333336667777 PP Abhydrolase_6 108 laallaalaapawlaae.......slargflddtp.......a..............daawaaalarlaallaalallplaawadlpapv...... 169 l +++++++ + w ++ + r ++++++ a d++++ a +++l + FUN_002382-T1 237 LDQWNGLRRLYNWGMTQnmkkiidRHVRVLFEGPNftshrhkAsihhvrsssslaelDDVYTKK---------------MAGFHHLDDFYarsscc 317 7777777777888866666777665555777766643322210111111122222223333333...............33333333333444555 PP Abhydrolase_6 170 ..........lvl.gteDrlvpelaqrllaalagarlp.......vvlpgaGHlpll 208 l+l + +D+lvpe + ++ +++ v+ ++GHl ++ FUN_002382-T1 318 nyinqvqipvLLLnSLDDPLVPEE--LYVT--PHNHVKsnesaifVITRHGGHLGFF 370 555555555566677889977744..3333..44444344444449999****8887 PP >> DUF915 Alpha/beta hydrolase of unknown function (DUF915) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 3.3e-06 0.0083 88 130 .. 175 217 .. 171 235 .. 0.90 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 3.3e-06 DUF915 88 wlkkvlseLkkkYnikkfnavGhSmGglaltsYleeyaddksl 130 l++v+++L +k n k++ vG+SmG+ l++Yl e + +++ FUN_002382-T1 175 ELDAVVTHLTSKLNHKRLVGVGFSMGANILMKYLGEIPSRQEY 217 6899******************************988776665 PP >> Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 1.1e-05 0.028 177 257 .. 274 363 .. 81 368 .. 0.59 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 1.1e-05 Peptidase_S15 177 r.......yeaageellaeldrqtfvleelletgdydafWksrslsedldkvkapvllvgGwqDwnvk.ngaiklyealkapg...klilgp 257 + ++ + laeld+ + ++++ + d+f + s+++++++v++pvll++++ D v + + ++++k+++ +i + FUN_002382-T1 274 ShrhkasiHHVRSSSSLAELDDV--YTKKMAGFHHLDDFYARSSCCNYINQVQIPVLLLNSLDDPLVPeELYVTPHNHVKSNEsaiFVITRH 363 13333443344555666677766..99*************************************6666444455677787777543333344 PP >> Ndr Ndr family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 7.3e-06 0.019 20 123 .. 113 214 .. 108 365 .. 0.83 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 7.3e-06 Ndr 20 eekkpvllTyhDlglnhkscFqelfnsesmaeilekfvilhvdaPGqeegaaslpedyqypslddladqllavldhfklksviglGvgaGAyilar 115 +++k ++ ++ ++ +++ + + f +m++ +v+ h+ a ++++ s p+ ++y ++l ++++ +++ k ++g+G GA+il++ FUN_002382-T1 113 NQEKLTIVIVPGIANCSETQYVRTFADYAMNQGFRVAVLNHLGA--KKKEGLSTPRLFTYGGTEELDAVVTHLTSKLNHKRLVGVGFSMGANILMK 206 45688889999999999999999999999998888888888877..56667778888999999999999999************************ PP Ndr 116 falkhper 123 + + p+r FUN_002382-T1 207 YLGEIPSR 214 97776666 PP >> Peptidase_S9 Prolyl oligopeptidase family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.0 0.00035 0.9 61 124 .. 187 254 .. 136 262 .. 0.84 2 ? 3.1 0.0 0.032 81 111 160 .. 296 340 .. 269 371 .. 0.66 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.00035 Peptidase_S9 61 vdeerlaitGgSyGGyltlaaln...qrpdlFkaavaeapvvdwlaydsdtdlpfte.eymewgnpdd 124 +++rl+ G S G ++ l+ r++ F+++++++ +d l+ +++ d++ + + +wg +++ FUN_002382-T1 187 LNHKRLVGVGFSMGANILMKYLGeipSRQEYFECGISVCQGYDILRAKTFLDQWNGLrRLYNWGMTQN 254 5789*************9999996667999********************999888888888887744 PP == domain 2 score: 3.1 bits; conditional E-value: 0.032 Peptidase_S9 111 pfteeymewgnpddneegyeelspysplenvkaypplLlihGleDdrvpp 160 ++t+++ ++ + y ++s+ ++ n +++ p+Ll+ +l D+ vp FUN_002382-T1 296 VYTKKMAGFHH---LDDFY-ARSSCCNYIN-QVQIPVLLLNSLDDPLVPE 340 56664444333...34556.6677666666.69************99975 PP >> VirJ Bacterial virulence protein (VirJ) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 3.1e-05 0.08 51 92 .. 174 215 .. 164 219 .. 0.91 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 3.1e-05 VirJ 51 adlariiktyrkrwkakrvvliGysfGadvlPaaynklpakt 92 ++l++++++ +++ ++kr+v +G+s+Ga++l ++p+++ FUN_002382-T1 174 EELDAVVTHLTSKLNHKRLVGVGFSMGANILMKYLGEIPSRQ 215 6899***************************99988888765 PP >> ANTH ANTH domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.00011 0.28 222 260 .. 291 329 .. 280 338 .. 0.87 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00011 ANTH 222 dkaldiykrfskqferlkeFyevckslgylrsleiPklp 260 +++ d+y++ + f++l++Fy +++ +y ++ +iP l FUN_002382-T1 291 AELDDVYTKKMAGFHHLDDFYARSSCCNYINQVQIPVLL 329 6788999*****************************985 PP >> N_formyltrans_C N-formyltransferase dimerization C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.4 0.0 0.016 42 28 43 .. 102 116 .. 100 121 .. 0.85 2 ? 4.9 0.0 0.012 30 21 31 .. 229 239 .. 227 242 .. 0.86 Alignments for each domain: == domain 1 score: 4.4 bits; conditional E-value: 0.016 N_formyltrans_C 28 fppyknAyfiddtGek 43 f+p knA f+++ ek FUN_002382-T1 102 FEPAKNAVFVEN-QEK 116 9**********9.555 PP == domain 2 score: 4.9 bits; conditional E-value: 0.012 N_formyltrans_C 21 DvLRArTfppy 31 D+LRA+Tf + FUN_002382-T1 229 DILRAKTFLDQ 239 9*******886 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (417 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 943 (0.0369152); expected 510.9 (0.02) Passed bias filter: 827 (0.0323742); expected 510.9 (0.02) Passed Vit filter: 69 (0.00270112); expected 25.5 (0.001) Passed Fwd filter: 10 (0.000391466); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.34u 0.38s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 4170.81 // Query: FUN_002384-T1 [L=474] Description: FUN_002384 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-37 130.1 18.4 2.2e-37 129.4 18.4 1.3 1 7tm_1 7 transmembrane receptor (rhodopsin family) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.4 18.4 8.7e-42 2.2e-37 1 260 [] 56 415 .. 56 415 .. 0.94 Alignments for each domain: == domain 1 score: 129.4 bits; conditional E-value: 8.7e-42 xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrt.ptnifllnLavaDllvlllvlpfalvyallegdwvfgevlCklvtaldvvnltasillltaisiDRYlaIvkplkykr 95 gN++V ++i+rn++lr+ p+n++llnL+ +D+l+ ll++pf lv + ++ w++g++lC+++ +++ t s l+l +is+DR+ +++p+ FUN_002384-T1 56 GNGMVFYLICRNRRLRQtPSNMLLLNLSACDFLTPLLSIPFDLVLEERGYVWPYGSFLCHVLWPASTLTATLSALTLSVISLDRFRLLMHPFTP-- 149 8**************9989************************99999**********************************************.. PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF 7tm_1 96 irtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks.. 189 + tk++ ++li+++ +l+l +++p ++f + e+++C ++p+ +++++ytl+l+v + lpl++++++y++ l +l++ ++++s FUN_002384-T1 150 RLTKTQIKFLIAGIHLLSLSVIVPYVVFLKL-------EDNMCIEQWPK--LWYRQVYTLVLFVTQYALPLFFMTTVYALALIKLYNVTSNASSmr 236 89**************************986.......4679*******..66999************************************99** PP ................................................................................................ RF 7tm_1 190 ................................................................................................ 189 FUN_002384-T1 237 vkeentssrrsrevsvnsrgvstnsrdvsdnsrkvseslrtssensrqvsinsrevsansckvtvssrkssvisrkvssssqlscetnndlfrngn 332 ***************************************************************************************999999999 PP .............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 .............kkkksarkerkalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 k+ + ++ +++k+ +++v++f++++lP ++l l+ + + +++ ++ +++i+ l++y+n++ NP+i+ FUN_002384-T1 333 rirrlssrvaynvKQGCEIDSNVRVTKLFIAIVAIFAIFMLPNQVLWLWIDF-GAGLRHERLNIVKIICWLFTYTNCVCNPVIF 415 88777766666654444444455**************************999.889999999********************95 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (474 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1426 (0.0558231); expected 510.9 (0.02) Passed bias filter: 500 (0.0195733); expected 510.9 (0.02) Passed Vit filter: 39 (0.00152672); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.39u 0.38s 00:00:00.77 Elapsed: 00:00:00.42 # Mc/sec: 4501.24 // Query: FUN_002385-T1 [L=298] Description: FUN_002385 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-60 204.6 1.1 2.2e-60 204.2 1.1 1.1 1 rva_4 Integrase core domain 4e-07 30.7 0.0 7e-07 29.9 0.0 1.4 1 rve Integrase core domain Domain annotation for each model (and alignments): >> rva_4 Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 204.2 1.1 1.7e-64 2.2e-60 1 188 [. 65 250 .. 65 255 .. 0.98 Alignments for each domain: == domain 1 score: 204.2 bits; conditional E-value: 1.7e-64 rva_4 1 vykvatPnslWhidgnmklirWrlvvhGaidgysrlivyleastnnrastvlkqflkavkkyglPsrvrsdkggenvkvallmnllrGlerssvit 96 vy+v +Pn lWh+dgn+klirW++vvh +idg+srl+++ ++st+n+a t++ f +av +yg P r+rsd g env v + m + G++ +svi FUN_002385-T1 65 VYSVRYPNYLWHLDGNHKLIRWKFVVHHSIDGFSRLVTFCRCSTKNKAETLFLAFKEAVGRYGRPQRIRSDLGEENVLVWRDMTSAWGKDARSVIV 160 8*********************************************************************************************** PP rva_4 97 GrsvhnqrierlWrdvfkkvvsvfyslftaledseildidndihllalhivylpriqkeleefknawnnhklrteknktPlqlfveglleni 188 G svhnqr er r v+++ +svf+s f+ le ++ld+ n+++l+++++vylpr++++l ef +++nnhk++te n + + ++++ l+ FUN_002385-T1 161 GSSVHNQRSERHNRSVNEHKLSVFKSEFYDLE--GVLDPLNETDLFCFRYVYLPRLNENLAEFVSSHNNHKISTESNTSAHMFWTSLHLTAF 250 *******************************8..79************************************************99888765 PP >> rve Integrase core domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.0 5.5e-11 7e-07 4 91 .. 71 152 .. 69 163 .. 0.89 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 5.5e-11 rve 4 pnqlwqgDityikvpgkggklyllvivDdfsreivawalssemsaetvlaalekaiakrggvkpkiihsDngseftskefqeflkelg 91 pn+lw+ D + +++ + +++ +D fsr ++ +++s++++aet++ a ++a+ ++g p++i+sD g e + ++++++++g FUN_002385-T1 71 PNYLWHLDGNHKL-IRWK--FVVHHSIDGFSRLVTFCRCSTKNKAETLFLAFKEAVGRYGR--PQRIRSDLGEENV-LVWRDMTSAWG 152 99*******9766.4455..*****************************************..*********9988.77777777766 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (298 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 622 (0.0243492); expected 510.9 (0.02) Passed bias filter: 533 (0.0208651); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 3032.80 // Query: FUN_002386-T1 [L=619] Description: FUN_002386 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-13 51.3 0.0 3.7e-13 50.3 0.0 1.5 1 HECT HECT-domain (ubiquitin-transferase) ------ inclusion threshold ------ 1.2 9.9 4.2 30 5.4 0.3 3.1 3 DUF7480 Domain of unknown function (DUF7480) Domain annotation for each model (and alignments): >> HECT HECT-domain (ubiquitin-transferase) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.3 0.0 2.9e-17 3.7e-13 27 306 .. 348 618 .. 322 619 .] 0.74 Alignments for each domain: == domain 1 score: 50.3 bits; conditional E-value: 2.9e-17 xxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF HECT 27 fnpesseee...klelfkllGkllGkaiyegllldlpfpraflkkllg...kekltledleeidpelakslksLlelkedeeevedleltFtvsee 116 + ++++++l+G++l+ ++ +g + f+ ++ ++ k++ +led++ d++l++++ ++ + k+d+e +e+ +l FUN_002386-T1 348 Y-------NiarEKDFYRLVGVVLAWSLAHGGPAGNFFSGTLYDSIAYgpgKRPPKLEDIA--DEDLKQKIIKIADSKTDKE-LEK-NL--H---- 426 2.......02334578*******************************98888899988886..899********97766653.322.22..2.... PP xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx..xxxxxx RF HECT 117 sfgekktveLipn.GsnipVtnenveeYiklvvdyrlnksiekqleafrkGfssvipkealklftpeelellicGse.evidvedlkk..ntkyeg 208 +++ + L + ++ +V+ +++++ ++ + l +s + le++++G++++ ea+k pe+++ l+ ++ +d+ + + +++y+g FUN_002386-T1 427 --DDEIQRILDAQgAAKLSVKLSDKDSIVNIILRDVLVDSTRYLLEELKEGLKTLGVLEAIKK-HPEQFRELFTKENiRPLDFATVDAifHIDYDG 519 ..3333344665516789*************************************99999998.67777777777774356666555511566666 PP xxxxxx........xxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxx RF HECT 209 gytkes........kvikwfweileefse....eerrklLkFvTgssrlPlgGfkslpkltIqkksgkdddrLPtahTCfnlLklp.eYsskeilk 291 + ++e ++l++ ++ r+ L F+Tg + P+ G + + I++ +d+r+Pta+TC L lp +Y+++e++k FUN_002386-T1 520 EASNERavqdltifH----WKNYLQDCESgdagATLRDVLSFATGADAPPVLGDSPV----ITF----QDTRFPTANTCARILRLPtKYETYEEFK 603 544443555433322....23444444432222689****************99966....777....469***************88******** PP xxxxxxxxxxxxxxx RF HECT 292 ekLliAieegegFgl 306 +++ + i ++ gFg FUN_002386-T1 604 KNMDFGILNSLGFGH 618 **********99985 PP >> DUF7480 Domain of unknown function (DUF7480) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.9 0.4 0.0033 42 6 32 .. 122 148 .. 117 153 .. 0.86 2 ? 5.4 0.3 0.0024 30 4 45 .. 149 189 .. 147 197 .. 0.81 3 ? -1.4 0.0 0.3 3.8e+03 51 75 .. 278 302 .. 256 311 .. 0.77 Alignments for each domain: == domain 1 score: 4.9 bits; conditional E-value: 0.0033 DUF7480 6 vllkdnqvCisvpaekdekilsieIee 32 ++ d+++C+ +++ ++++ s++I + FUN_002386-T1 122 CHMTDKKPCVVTTQSDEKEVESMDIDN 148 6789********************965 PP == domain 2 score: 5.4 bits; conditional E-value: 0.0024 DUF7480 4 anvllkdnqvCisvpaekdekilsieIeesggekellekdfs 45 ++v + +++C+ +++ ++++ s++I + +++ + k +s FUN_002386-T1 149 DTVCHMTDKPCVVTTQSDEKEVESMDIDN-DTVCHMTDKGYS 189 67788899*******************76.666666666665 PP == domain 3 score: -1.4 bits; conditional E-value: 0.3 DUF7480 51 vksgqClpvfgykFeagkeYsvsit 75 + ++ C ++ g +F+++++ sv++ FUN_002386-T1 278 IWEDTCRQLMGKRFSPNNRISVKFV 302 4567788888888888888777764 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (619 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1298 (0.0508123); expected 510.9 (0.02) Passed bias filter: 811 (0.0317479); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.39u 0.36s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 6140.68 // Query: FUN_002388-T1 [L=329] Description: FUN_002388 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0089 17.2 2.1 0.0089 17.2 2.1 2.2 3 Sfi1_C Spindle body associated protein C-terminus ------ inclusion threshold ------ 0.77 11.3 3.9 2.1 9.9 3.3 2.2 2 SmAKAP Small membrane A-kinase anchor protein 1.2 9.9 6.3 3.1 8.6 3.8 2.5 2 BORCS7 BLOC-1-related complex sub-unit 7 Domain annotation for each model (and alignments): >> Sfi1_C Spindle body associated protein C-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.5 0.1 0.69 5.9e+03 72 96 .. 31 55 .. 2 58 .. 0.48 2 ! 17.2 2.1 1e-06 0.0089 46 91 .. 118 163 .. 111 173 .. 0.86 3 ? -3.3 0.1 2.5 2.2e+04 77 90 .. 207 220 .. 197 227 .. 0.50 Alignments for each domain: == domain 1 score: -1.5 bits; conditional E-value: 0.69 Sfi1_C 72 keeksppklklekinkklaskvkei 96 ++ + klkle+++ l s+ ++ FUN_002388-T1 31 SKVTESSKLKLEEKGCPLTSSLSNY 55 2222245666666666666665555 PP == domain 2 score: 17.2 bits; conditional E-value: 1e-06 Sfi1_C 46 PsPikssdvldstvkrklekeeksaakeeksppklklekinkklas 91 PsP k s+ + t+kr+l k+++s+ +e k++++l+++++ + + FUN_002388-T1 118 PSPEKRSKLVRETAKRRLVKQANSKDEEAKAAKRLAIKEEAMEEKA 163 *************************************987655444 PP == domain 3 score: -3.3 bits; conditional E-value: 2.5 Sfi1_C 77 ppklklekinkkla 90 +++ +l++i +k++ FUN_002388-T1 207 VNQQNLQRIVRKIE 220 33444444444444 PP >> SmAKAP Small membrane A-kinase anchor protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 1.4 1.2e+04 20 65 .. 32 56 .. 6 65 .. 0.57 2 ? 9.9 3.3 0.00024 2.1 11 79 .. 126 193 .. 119 222 .. 0.70 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1.4 SmAKAP 20 kqkekeekfkpeealarlaskvlvqeevkespeesaevspvlleyA 65 k++e+++ +e+++ + l +y FUN_002388-T1 32 KVTESSKLK---------------------LEEKGCPLTSSLSNYS 56 222333333.....................3334455555555555 PP == domain 2 score: 9.9 bits; conditional E-value: 0.00024 SmAKAP 11 pfpttlelekqkekeekfkpeealarlaskvlvqeevkespeesaevspvlleyAqrLseeivadAlqq 79 +++t + +k+ + k ++ +a++rla k ++ ee +e++++ s lle + L+ +i+ d ++q FUN_002388-T1 126 LVRETAKRRLVKQANSKDEEAKAAKRLAIKEEAMEEKA-REEDNLSQSKELLEISDELTTDILYDFMKQ 193 44444433333333333333344466666665555544.5566689999****************9999 PP >> BORCS7 BLOC-1-related complex sub-unit 7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.6 3.8 0.00036 3.1 34 75 .. 131 175 .. 127 211 .. 0.75 2 ? 0.8 0.2 0.092 7.8e+02 20 41 .. 201 222 .. 199 226 .. 0.84 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00036 BORCS7 34 vakqivkgSksseilmkaaknfaqqetaient...eesLkkmsll 75 + +vk ++s++ kaak +a+ e+a+e+ e++L + + l FUN_002388-T1 131 AKRRLVKQANSKDEEAKAAKRLAIKEEAMEEKareEDNLSQSKEL 175 5689*************************9876667888776665 PP == domain 2 score: 0.8 bits; conditional E-value: 0.092 BORCS7 20 Laervqvnvndissvakqivkg 41 + ++v+vn ++++ ++++i k FUN_002388-T1 201 IEKKVDVNQQNLQRIVRKIEKQ 222 5689999999999999999885 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (329 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2504 (0.0980231); expected 510.9 (0.02) Passed bias filter: 960 (0.0375807); expected 510.9 (0.02) Passed Vit filter: 91 (0.00356234); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.40 # Mc/sec: 3347.45 // Query: FUN_002389-T1 [L=157] Description: FUN_002389 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (157 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 608 (0.0238011); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.26u 0.39s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1579.14 // Query: FUN_002390-T1 [L=119] Description: FUN_002390 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (119 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 980 (0.0383637); expected 510.9 (0.02) Passed bias filter: 780 (0.0305344); expected 510.9 (0.02) Passed Vit filter: 42 (0.00164416); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.39s 00:00:00.66 Elapsed: 00:00:00.41 # Mc/sec: 1174.57 // Query: FUN_002391-T1 [L=116] Description: FUN_002391 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-11 44.2 0.0 2.6e-11 44.0 0.0 1.1 1 DEAD DEAD/DEAH box helicase 0.00023 21.6 0.0 0.00025 21.5 0.0 1.1 1 ResIII Type III restriction enzyme, res subunit Domain annotation for each model (and alignments): >> DEAD DEAD/DEAH box helicase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.0 0.0 2e-15 2.6e-11 3 71 .. 17 86 .. 15 102 .. 0.90 Alignments for each domain: == domain 1 score: 44.0 bits; conditional E-value: 2e-15 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF DEAD 3 iQaeaipallegkdvlvqapTGsGKTlafllpileal.kkkkegpqalvlaPtreLaeqiveelkkllkk 71 Q++ai +ll+g+dvl++ TG GK+++f + ++++ k + + ++lv++P+++++ +++ +l+ l++ FUN_002391-T1 17 EQKQAIVSLLNGEDVLAVLSTGLGKSMIFTVFAIAESeKLEGSPVSVLVICPLKSIISDQIVQLEGLCSA 86 6*********************************99967799999****************999988874 PP >> ResIII Type III restriction enzyme, res subunit # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 1.9e-08 0.00025 4 79 .. 14 86 .. 11 110 .. 0.74 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 1.9e-08 ResIII 4 lrpyQeeaiealleklkkgekrglivmaTGsGKTlva..akliarlskkgkekkvlflvdrkeLleqakeefkkflse 79 l+ Q++ai +ll + + +l v+ TG GK+++ ++++++ + +g+ vl++++ k++++ +++ + s FUN_002391-T1 14 LKREQKQAIVSLL-----NGEDVLAVLSTGLGKSMIFtvFAIAESEKLEGSPVSVLVICPLKSIISDQIVQLEGLCSA 86 6788999999999.....7899************9985234444444444444**********999877666665554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (116 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 441 (0.0172637); expected 510.9 (0.02) Passed bias filter: 401 (0.0156978); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.37s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1188.40 // Query: FUN_002392-T1 [L=419] Description: FUN_002392 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (419 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 968 (0.0378939); expected 510.9 (0.02) Passed bias filter: 771 (0.030182); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.41s 00:00:00.73 Elapsed: 00:00:00.40 # Mc/sec: 4188.31 // Query: FUN_002394-T1 [L=198] Description: FUN_002394 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (198 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 906 (0.0354668); expected 510.9 (0.02) Passed bias filter: 571 (0.0223527); expected 510.9 (0.02) Passed Vit filter: 25 (0.000978665); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 2022.52 // Query: FUN_002395-T1 [L=336] Description: FUN_002395 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (336 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1516 (0.0593463); expected 510.9 (0.02) Passed bias filter: 934 (0.0365629); expected 510.9 (0.02) Passed Vit filter: 81 (0.00317087); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.37u 0.38s 00:00:00.75 Elapsed: 00:00:00.41 # Mc/sec: 3266.56 // Query: FUN_002397-T1 [L=443] Description: FUN_002397 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (443 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1034 (0.0404776); expected 510.9 (0.02) Passed bias filter: 517 (0.0202388); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.34u 0.40s 00:00:00.74 Elapsed: 00:00:00.42 # Mc/sec: 4281.23 // Query: FUN_002398-T1 [L=187] Description: FUN_002398 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.5e-05 22.8 0.3 0.032 14.4 0.0 2.1 2 KDZ Kyakuja-Dileera-Zisupton transposase Domain annotation for each model (and alignments): >> KDZ Kyakuja-Dileera-Zisupton transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 7.2 0.1 0.0002 5.2 48 112 .. 33 109 .. 5 122 .. 0.63 2 ! 14.4 0.0 1.2e-06 0.032 163 206 .. 120 163 .. 113 173 .. 0.82 Alignments for each domain: == domain 1 score: 7.2 bits; conditional E-value: 0.0002 KDZ 48 k.......ek....stCasrwkaaae.aetkktwkgfdetGifavlC.rHglvlgvadlvksgelakydlalvsklle 112 + ++ ++C+++ ++ + +++++ +f++t +++l g+v +++++ s+ + ++ ++ vsk +e FUN_002398-T1 33 EfnsaraeADllpeDECEAQ-QNEKGcKKKENILLFFQTTAGMLALIrPCGIVVSMTEMFTSESYTQTFFTPVSKHTE 109 03333332113444999555.55555255555666777777777777356777*************999999988777 PP == domain 2 score: 14.4 bits; conditional E-value: 1.2e-06 KDZ 163 CqlryspnyiegvGledgEgcErlwsksnalasstreaspghrh 206 C ++ ++ + + + E cE+ + +n+ tr++++++r FUN_002398-T1 120 CLYHPHLPKFDEIRGVNTESCEQGFKRLNQYFELTRKMTQFKRN 163 555555555556666689***********************997 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (187 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 753 (0.0294774); expected 510.9 (0.02) Passed bias filter: 536 (0.0209826); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.39s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 1878.58 // Query: FUN_002400-T1 [L=325] Description: FUN_002400 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0092 16.5 1.9 0.034 14.7 0.2 2.4 2 NSF_ATPase_lid NSF, AAA+ ATPase lid domain ------ inclusion threshold ------ 6.9 7.5 8.0 3.7 8.4 2.3 2.3 2 Corazonin Pro-corazonin Domain annotation for each model (and alignments): >> NSF_ATPase_lid NSF, AAA+ ATPase lid domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.1 0.082 1e+03 5 33 .. 106 133 .. 104 137 .. 0.75 2 ! 14.7 0.2 2.7e-06 0.034 1 38 [. 168 207 .. 168 209 .. 0.93 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.082 NSF_ATPase_lid 5 pehllavLeeldvFtkkelasiakkvkgk 33 +e++l+ ee++ F kk+ + + k ++ FUN_002400-T1 106 AEDVLSDKEEVNRFPKKQPKLLRKT-SKR 133 68999999******99987766554.444 PP == domain 2 score: 14.7 bits; conditional E-value: 2.7e-06 NSF_ATPase_lid 1 NlstpehllavLeeldv..FtkkelasiakkvkgkrvfiG 38 Nls++++ll++ +el + ++++l++i k++ ++vf+G FUN_002400-T1 168 NLSQSKELLEISDELTAvdVNQQNLERIVGKIETQKVFLG 207 9***********99987567899***************99 PP >> Corazonin Pro-corazonin # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.4 2.3 0.00029 3.7 65 117 .. 126 178 .. 121 192 .. 0.84 2 ? 2.1 0.3 0.026 3.4e+02 53 130 .. 221 298 .. 208 301 .. 0.69 Alignments for each domain: == domain 1 score: 8.4 bits; conditional E-value: 0.00029 Corazonin 65 llvrsvalnlarsdsdsedsssksslnnnnnnnvlnslspknrnrqsnelfEe 117 ll ++++ l ++++d +++++ ++ ++++ ++++++++++ qs el+E FUN_002400-T1 126 LLRKTSKRRLVKQANDKDEEAKAAKRLAKKEEAMEEKATQEDNLSQSKELLEI 178 6778888899999999999999999999999********************94 PP == domain 2 score: 2.1 bits; conditional E-value: 0.026 Corazonin 53 CLsqLqrsvlnrllvrsvalnlarsdsdsedsssksslnnn..nnnnvlnslspknrnrqsnelf.Eelsaagadsvepnd 130 CL L++s l + + +s + nl+++++++++ s+ + n + ++v+++ s + + + + e++ Ee+ + g+++ e nd FUN_002400-T1 221 CL--LKKSCLDPTICSSPKGNLKTNEPPASSCSKLVDSGNCsfDSDDVNVTESSSPNGEYTAEILpEEI-SNGSSPEEVND 298 55..67889999999999999999999887766544443333556666666666667777777763666.77777777776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (325 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2588 (0.101311); expected 510.9 (0.02) Passed bias filter: 976 (0.0382071); expected 510.9 (0.02) Passed Vit filter: 90 (0.00352319); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 3221.84 // Query: FUN_002401-T1 [L=204] Description: FUN_002401 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-13 51.0 0.0 1.9e-13 50.6 0.0 1.1 1 Mutator Mutator-like transposase Domain annotation for each model (and alignments): >> Mutator Mutator-like transposase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.6 0.0 7.3e-18 1.9e-13 67 114 .. 143 192 .. 132 199 .. 0.86 Alignments for each domain: == domain 1 score: 50.6 bits; conditional E-value: 7.3e-18 Mutator 67 e.kr.gkrGpkafdvNrklvlallklgvGptqlnellaalniPpvsestl 114 + ++ g rGpka d+N+++vl++l+lgvG+tqln++la+lniP+++++ FUN_002401-T1 143 DdNEaGSRGPKASDINSRAVLGSLHLGVGQTQLNNFLATLNIPTMNSQLV 192 3345599***************************************9865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (204 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 812 (0.031787); expected 510.9 (0.02) Passed bias filter: 509 (0.0199256); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.40s 00:00:00.69 Elapsed: 00:00:00.40 # Mc/sec: 2033.65 // Query: FUN_002402-T1 [L=362] Description: FUN_002402 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-46 158.2 14.4 5e-46 157.8 14.4 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.6e-11 44.6 12.7 3.2e-11 43.6 12.7 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 4.7e-10 40.0 9.9 8.7e-10 39.1 9.8 1.5 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 1.3e-08 35.0 14.5 2.2e-05 24.4 2.3 2.2 2 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00075 19.8 11.6 0.016 15.4 11.6 2.3 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.25 12.0 0.6 8.4 7.0 0.0 2.7 2 DUF3974 Domain of unknown function (DUF3974) 1.1 9.1 7.3 0.064 13.1 0.7 2.1 2 DUF3810 Protein of unknown function (DUF3810) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 157.8 14.4 1.4e-49 5e-46 1 260 [] 23 280 .. 23 280 .. 0.92 Alignments for each domain: == domain 1 score: 157.8 bits; conditional E-value: 1.4e-49 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvll.lvlpfalvyallegdwvfgevlCklvt..aldvvnltasillltaisiDRYlaIvkplky 93 gN lV++vil+n+ +rt++n++llnLa+aD+ v++ ++ +l++a + d +g++lCkl+t + + ++as+++++ai+i+RY a+++pl + FUN_002402-T1 23 GNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVfFASRYTLIHAYNHPDGNVGTILCKLLTggTFGWIGSCASVFTMVAIAIERYYAVTRPLGN 118 8******************************99985666777788888999**********97446899*************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 ++ tk +v+i + W+++++l+lp +l +k+++ ++ + C+ ++p ++++ y ll++vl +p++v++v+y+r++ tl+ +++++ FUN_002402-T1 119 RATFTKDSLKVIISASWIFGIILCLPDFL---VKDFC--ESYRACVGNWPPAHAWMPKAYSLLWTVLLTAIPVSVMTVLYSRVILTLWVKPSRAIG 209 ***************************99...56787..789*********9889*********************************99999877 PP xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 kkkksarker...kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ +++ ++r ++++++lvv v+f++cw+ + +l ++ ++ l ++ i++ l ++ns +NPi+Y FUN_002402-T1 210 NDPSEQGRSRvrkRVTTMVLVVSVIFAFCWITECTDYTLLVF---FPKLALGNATHVISSTLVMFNSSINPIVY 280 4444444444444**********************9999999...9999999*********************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.6 12.7 8.8e-15 3.2e-11 2 256 .. 18 294 .. 17 295 .. 0.78 Alignments for each domain: == domain 1 score: 43.6 bits; conditional E-value: 8.8e-15 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvlllt.....gtqlkreeCFlli..ivyvfgltaqsvllLvigiDlliav 90 vv l+GN+l+ +++k++ +r+ +++L+ +++ad+ ++v+ ++ + l++ + ++ C ll ++ +g +a+ +++i+i + +av FUN_002402-T1 18 VVALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVFF-ASRYTLIHaynhpDGNVGTILCKLLTggTFGWIGSCASVFTMVAIAIERYYAV 112 899********************************9776653.33333333000113344455686654447999********************* PP 7TM_GPCR_Srsx 91 kfPirYrllskekYllillifpvlyssiilvlgflqrdde.tiivCa....pplalagkas.eiftlssliinvivllv.ylvliiilkkkkek.. 177 + P+ r ++ l + + ++ +i+ + +fl+ d +C p a +ka+ ++t++ +i v+v+ v y +i++l k ++ FUN_002402-T1 113 TRPLGNRATFTKDSLKVIISASWIFGIILCLPDFLVKDFCeSYRACVgnwpPAHAWMPKAYsLLWTVLLTAIPVSVMTVlYSRVILTLWVKPSRai 208 *********9999***********************9975477778544434455556665378*********99986626666666666655578 PP 7TM_GPCR_Srsx 178 ....kkssskkvlkslkvtv....vififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +++ ++v k+++++v vif f+W+t + t+l+ + + ++ + ++ ++lv++++s n +V+ ++s+++r++++++ FUN_002402-T1 209 gndpSEQGRSRVRKRVTTMVlvvsVIFAFCWITECTDYTLLVFF-PKLALGNATHVISSTLVMFNSSINPIVYALISHRFRDEIIRM 294 88886666666777776666333368999**9998888888855.5677888999999**************************998 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.1 9.8 2.4e-13 8.7e-10 6 229 .. 19 248 .. 15 280 .. 0.71 Alignments for each domain: == domain 1 score: 39.1 bits; conditional E-value: 2.4e-13 7TM_GPCR_Srx 6 iGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsell...kellnshliglialglYeisplsqllialNRfcavff 98 + lv N+lv +ilk+ +++ ++l l+ ai++++++++f+ ++ + + +++ + + l++ ++g+++++ ++s ++ + ia++R +av FUN_002402-T1 19 VALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVFFASRYTLIHAYNHPDGnvgTILCKLLTGGTFGWIGSCASVFTMVAIAIERYYAVTR 114 55788*********************************99999999999988887755566777789***************************** PP 7TM_GPCR_Srx 99 plkyekifsiknTkiiiviiwivslifitvlylpegCkllynpetltwsfee..teccktiswyldfllililviitlvlnlltaikli..lskkk 190 pl f++ + k+ii+++wi+ +i ++ +l+++ +y + + +w + + ++++ w + +l+ + + ++t++ ++++ + ++ FUN_002402-T1 115 PLGNRATFTKDSLKVIISASWIFGIILCLPDFLVKDFCESYRACVGNWPPAHawMPKAYSLLWTV-LLTAIPVSVMTVLYSRVILTLWVkpSRAIG 209 *****************************999999888899*******77653344455555555.444444444444444444444332222222 PP 7TM_GPCR_Srx 191 skstsseeskrrrkreinffkQsvlQdllflidlvnyfl 229 + +++ s+ r++ +++ ++ sv+ +++ +++ + y+l FUN_002402-T1 210 NDPSEQGRSRVRKRVTTMVLVVSVIFAFCWITECTDYTL 248 222333334444444555555566555555555544443 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 4.6 2e-06 0.0072 2 136 .. 12 141 .. 11 158 .. 0.72 2 ! 24.4 2.3 5.9e-09 2.2e-05 192 318 .. 173 297 .. 165 298 .. 0.84 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 2e-06 7TM_GPCR_Srw 2 vefilsivgviinifHli.iLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlg 96 v+ ++ +v+++ n + + iL ++ mrt ++n+l+ ai+Di +++ +++ li+ +++ + + + k+l+ ++ + + +s++ + FUN_002402-T1 12 VQSVIVVVALVGNSLVCAvILKNRGMRT-TMNVLLLNLAIADITVVVFFASRYT--LIHAYNHPDGNVGTILCKLLTGG---TFGWIGSCASVFTM 101 5677888888888766650555666666.78************99999888887..77777666665555555555555...55555566699*** PP 7TM_GPCR_Srw 97 vlmAliRtlvvknplsnkiqklskpkfglliilivlllsl 136 v++A+ R+ v+ pl n++ + ++ +++ ++l FUN_002402-T1 102 VAIAIERYYAVTRPLGNRATFTKDSLKVIISASWIFGIIL 141 ******************9866555555555555555444 PP == domain 2 score: 24.4 bits; conditional E-value: 5.9e-09 7TM_GPCR_Srw 192 fllidgilskiipsillpiltilLiieLrkakksrkkls..kskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevi 285 + l+ +l++ ip ++ +l i L+ ++ ++ +++ +++ t +Vl+++++f + + y++ ++f k + + vi FUN_002402-T1 173 YSLLWTVLLTAIPVSVMTVLYSRVILTLWVKPSRAIGNDpsEQGRSRVRKRVTTMVLVVSVIFAFCWITECTDYTLLVFFPK----LALGNATHVI 264 55555666788888888888888888888776666666642344778999******************************99....67999999** PP 7TM_GPCR_Srw 286 fsllltinsisHflicllmSsqYRktvkklfgc 318 s+l+++ns++ +++ l+S++ R+ +++++++ FUN_002402-T1 265 SSTLVMFNSSINPIVYALISHRFRDEIIRMIRV 297 ******************************986 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 11.6 4.5e-06 0.016 2 277 .. 14 295 .. 13 297 .. 0.76 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 4.5e-06 7tm_4 2 clvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesa....vllamavdrf 93 +++ +++l+Gn+ + vi ++ + m ++l la++d+ + + + i + + + l +l+ +f + s+ +++a+a++r+ FUN_002402-T1 14 SVIVVVALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVFFASRYTLIHAYNHPDGNVGTILCKLLTGGTFGWIGSCasvfTMVAIAIERY 109 57889*************************************99999998889999999999999999999888887766541212467889**** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsyg 189 a+ +pl + +t+ + +i ++ +il lp fl++ + + ++ + + + + + + + + v v t +l s +i+ ++ FUN_002402-T1 110 YAVTRPLGNRATFTKDSLKVIISASWIFGIILCLP-DFLVKDFCESYRACVG-NWPPAHAWMPKAYSLLWTVLLTAIPVSVMT-VLYSRVILTLWV 202 ******************************99999.4666654332222332.233333333333333333344444444444.455666777788 PP 7tm_4 190 lilrtvlgiasreer...kkalntcgshvcavlaf..yvPmiglsvvhrfgkkvsrllqvllanlyllfPPvlnPivysvktkeirdavvkil 277 + r++ + +s ++r +k ++t + v +++af + +++ f k +++ ++f +nPivy++ + + rd +++++ FUN_002402-T1 203 KPSRAIGNDPSEQGRsrvRKRVTTMVLVVSVIFAFcwITECTDYTLLVFFPKLALGNATHVISSTLVMFNSSINPIVYALISHRFRDEIIRMI 295 888888888888888333467888888888888873235666677777788877777788899999*************************97 PP >> DUF3974 Domain of unknown function (DUF3974) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.1 0.063 2.3e+02 13 35 .. 44 66 .. 37 84 .. 0.79 2 ? 7.0 0.0 0.0023 8.4 9 41 .. 174 206 .. 167 221 .. 0.87 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 0.063 DUF3974 13 illllaitvvvllvyfgrklils 35 +ll lai+ ++++v+f ++ l FUN_002402-T1 44 LLLNLAIADITVVVFFASRYTLI 66 3566999*********9887654 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0023 DUF3974 9 lllgillllaitvvvllvyfgrklilswtkpyk 41 ll ++ll ai v v+ v + r ++ w kp + FUN_002402-T1 174 SLLWTVLLTAIPVSVMTVLYSRVILTLWVKPSR 206 578899*************************76 PP >> DUF3810 Protein of unknown function (DUF3810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 1.0 0.42 1.5e+03 29 75 .. 15 60 .. 3 71 .. 0.56 2 ? 13.1 0.7 1.7e-05 0.064 13 78 .. 177 239 .. 169 313 .. 0.76 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.42 DUF3810 29 ylllillllvylvkilklkkkkkkkkkllkfllkillflsilyflFl 75 ++++++l+ +lv+++ + k++ ++++ ll+++++ +++++F FUN_002402-T1 15 VIVVVALVGNSLVCAV-ILKNRGMRTTMNVLLLNLAIADITVVVFFA 60 2334444444555555.444555556666666666665555555554 PP == domain 2 score: 13.1 bits; conditional E-value: 1.7e-05 DUF3810 13 lsrlfgllpfSvgdllylllillllvylvkilklkkkkkkkkkllkfllkillflsilyflFlllw 78 + l+ +p+Sv+ +ly +il l v+ +++ ++ ++++ k +++++l++s ++F ++w FUN_002402-T1 177 WTVLLTAIPVSVMTVLYSRVILTLWVKPSRAIGNDPSEQGRSRVRKRVTTMVLVVS---VIFAFCW 239 5678899*************************444444444444444444444444...4444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (362 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1072 (0.0419652); expected 510.9 (0.02) Passed bias filter: 471 (0.0184381); expected 510.9 (0.02) Passed Vit filter: 36 (0.00140928); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.33u 0.40s 00:00:00.73 Elapsed: 00:00:00.41 # Mc/sec: 3598.55 // Query: FUN_002402-T2 [L=371] Description: FUN_002402 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-45 154.4 17.2 6.8e-45 154.1 17.2 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 1.1e-09 38.8 11.4 1.9e-09 38.0 11.4 1.4 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 4.8e-09 36.5 14.6 8.3e-09 35.7 14.6 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 7.6e-08 32.5 16.5 7.3e-06 26.0 16.5 2.2 1 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.0041 17.4 12.7 0.018 15.3 12.7 1.9 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 0.86 10.0 5.2 0.17 12.3 1.2 2.1 2 DUF5671 Domain of unknown function (DUF5671) 1.6 8.5 6.8 0.17 11.7 1.1 2.1 2 DUF3810 Protein of unknown function (DUF3810) Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 154.1 17.2 1.9e-48 6.8e-45 1 260 [] 32 289 .. 32 289 .. 0.93 Alignments for each domain: == domain 1 score: 154.1 bits; conditional E-value: 1.9e-48 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvll.lvlpfalvyallegdwvfgevlCklvt..aldvvnltasillltaisiDRYlaIvkplky 93 gN lV+++i++n +rt++n++llnLa+aD+ v++ ++ f l++a + d ++g+vlCkl+t + + ++as+++l+ai+i+RY a+++pl + FUN_002402-T2 32 GNSLVCAIIMKNPGKRTTMNCLLLNLAIADITVVAfFASRFILIQAYNHPDGKVGTVLCKLLTggTFGWIGSCASVFTLVAIAIERYYAVIRPLGN 127 8******************************9998577778888899999***********97446899*************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 ++ tk +v+i + W+++++l+lp +l +k+++ k+ + C+ ++p ++++ y+ll+++l+ +p++v++v+y+r++ tl+ +++++ FUN_002402-T2 128 RATFTKASLKVIIPASWIFGIILCLPDFL---VKDFC--KSYRACVANWPPAHAWMPKAYILLWTILIAAIPVSVMTVLYCRVVFTLWLRPSQAIA 218 ****************************9...56788..799*********9889*********************************99999888 PP xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 kkkksarker...kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ +++ ++r ++++++lvv v+f++cw+ + +l ++ ++ l ++ i++ l ++ns +NPi+Y FUN_002402-T2 219 HDPSEQGRSRvrkRVTTMVLVVSVIFAFCWITECTDYTLLVF---FPKLALGNATHVISSTLVMFNSSINPIVY 289 5555554444555**********************9999999...9999999*********************9 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 11.4 5.2e-13 1.9e-09 6 230 .. 28 258 .. 24 291 .. 0.75 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 5.2e-13 7TM_GPCR_Srx 6 iGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsell...kellnshliglialglYeisplsqllialNRfcavff 98 + lv N+lv +i+k++ +++ + l l+ ai++++++++f+ ++ +++ +++ + + l++ ++g+++++ ++s ++ + ia++R +av+ FUN_002402-T2 28 VALVGNSLVCAIIMKNPGKRTTMNCLLLNLAIADITVVAFFASRFILIQAYNHPDGkvgTVLCKLLTGGTFGWIGSCASVFTLVAIAIERYYAVIR 123 55788*********************************************99988755467778889***************************** PP 7TM_GPCR_Srx 99 plkyekifsiknTkiiiviiwivslifitvlylpegCkllynpetltwsfee..teccktiswyldfllililviitlvlnlltaikli.lskkks 191 pl f++ + k+ii ++wi+ +i ++ +l+++ +y + + +w + + ++++ w + + i + v+++l + ++ + l+ ++ + FUN_002402-T2 124 PLGNRATFTKASLKVIIPASWIFGIILCLPDFLVKDFCKSYRACVANWPPAHawMPKAYILLWTILIAAIPVSVMTVLYCRVVFTLWLRpSQAIAH 219 *****************************999998888899*******776544555666666654444444445555555555555554444444 PP 7TM_GPCR_Srx 192 kstsseeskrrrkreinffkQsvlQdllflidlvnyfli 230 +++ s+ r++ +++ ++ sv+ +++ +++ + y+l+ FUN_002402-T2 220 DPSEQGRSRVRKRVTTMVLVVSVIFAFCWITECTDYTLL 258 445555556666666666677777777666665555433 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.7 14.6 2.3e-12 8.3e-09 2 256 .. 27 303 .. 26 304 .. 0.77 Alignments for each domain: == domain 1 score: 35.7 bits; conditional E-value: 2.3e-12 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvlllt.....gtqlkreeCFlli..ivyvfgltaqsvllLvigiDlliav 90 +v l+GN+l+ +++k++ r+ +++L+ +++ad+ ++ + +++ ++l++ + ++ C ll ++ +g +a+ l++i+i + +av FUN_002402-T2 27 IVALVGNSLVCAIIMKNPGKRTTMNCLLLNLAIADITVVAF-FASRFILIQaynhpDGKVGTVLCKLLTggTFGWIGSCASVFTLVAIAIERYYAV 121 899********************************865543.444444443001113345556786665448999********************* PP 7TM_GPCR_Srsx 91 kfPirYrllskekYllillifpvlyssiilvlgflqrdde.tiivCa....pplalagkas.eiftlssliinvivllv.ylvliiilkkkkek.. 177 P+ r ++ l + + ++ +i+ + +fl+ d +C p a +ka+ ++t+++ +i v+v+ v y ++++l + ++ FUN_002402-T2 122 IRPLGNRATFTKASLKVIIPASWIFGIILCLPDFLVKDFCkSYRACVanwpPAHAWMPKAYiLLWTILIAAIPVSVMTVlYCRVVFTLWLRPSQai 217 ********9999888888888899***********999865566776223234566667764789*******999975538888888665555556 PP 7TM_GPCR_Srsx 178 ....kkssskkvlkslkvtv....vififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +++ ++v k+++++v vif f+W+t + t+l+ + + ++ + ++ ++lv++++s n +V+ ++s+++r++++++ FUN_002402-T2 218 ahdpSEQGRSRVRKRVTTMVlvvsVIFAFCWITECTDYTLLVFF-PKLALGNATHVISSTLVMFNSSINPIVYALISHRFRDEIIRM 303 67775555666666666555222368999**9998888888855.5677888999999**************************998 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 16.5 2e-09 7.3e-06 2 318 .. 21 306 .. 20 307 .. 0.79 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 2e-09 7TM_GPCR_Srw 2 vefilsivgviinifHliiLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlgv 97 v+ ++ iv+++ n + + i+++ + + +++n+l+ ai+Di + + ++i li+ +++ + + + k+l+ ++ + + +s++ v FUN_002402-T2 21 VQSVIVIVALVGNSLVCAIIMKNPGKRTTMNCLLLNLAIADITVVAFFASRFI--LIQAYNHPDGKVGTVLCKLLTG---GTFGWIGSCASVFTLV 111 68899*****************************************9999999..6666655555444444444444...455666666799**** PP 7TM_GPCR_Srw 98 lmAliRtlvvknplsnkiqklskpkfglliilivlllsllisilkyfrye.iveeeekwkppkeCaefpenysetkyvlvvselftandglllkif 192 ++A+ R+ v pl n++ +k++l++i+ +++ +i +l f ++ + ++ C + + ++ + k + FUN_002402-T2 112 AIAIERYYAVIRPLGNRAT---FTKASLKVIIPASWIFGIILCLPDFLVKdFCKSY------RACV------------ANWPPA----HAWMPKAY 182 ****************975...6788899998888777776666544443044222......3465............222222....22233455 PP 7TM_GPCR_Srw 193 llidgilskiipsillpiltilLiieLrkakksrkkls..kskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevif 286 +l+ il+ ip ++ +l + ++ L+ ++ ++ +++ +++ t +Vl+++++f + + y++ ++f k + + vi FUN_002402-T2 183 ILLWTILIAAIPVSVMTVLYCRVVFTLWLRPSQAIAHDpsEQGRSRVRKRVTTMVLVVSVIFAFCWITECTDYTLLVFFPK----LALGNATHVIS 274 6666777899999999999999999988777766666642444778999******************************99....67999999*** PP 7TM_GPCR_Srw 287 sllltinsisHflicllmSsqYRktvkklfgc 318 s+l+++ns++ +++ l+S++ R+ +++++++ FUN_002402-T2 275 STLVMFNSSINPIVYALISHRFRDEIIRMIRV 306 *****************************986 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 12.7 5e-06 0.018 2 277 .. 23 304 .. 22 306 .. 0.77 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 5e-06 7tm_4 2 clvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesa....vllamavdrf 93 +++ +++l+Gn+ + +i + m +l la++d+ + a + + i + + + l +l+ +f + s+ +l+a+a++r+ FUN_002402-T2 23 SVIVIVALVGNSLVCAIIMKNPGKRTTMNCLLLNLAIADITVVAFFASRFILIQAYNHPDGKVGTVLCKLLTGGTFGWIGSCasvfTLVAIAIERY 118 5789*****************************************************99999999999999888998776642222589******* PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsyg 189 a+++pl + +t+ + +i ++ +il lp fl++ + + +++ a ++ a i + +i ++ ++ +l + ++ FUN_002402-T2 119 YAVIRPLGNRATFTKASLKVIIPASWIFGIILCLP-DFLVKDFCKSYRACVANW---PPAHAWMPKAYILLWTILIA--AIPVSVMTVLYCRVVFT 208 *******************************9999.567765544444444433...23334556666666665433..33333445556666667 PP 7tm_4 190 lilrtvlgia...sreer...kkalntcgshvcavlaf..yvPmiglsvvhrfgkkvsrllqvllanlyllfPPvlnPivysvktkeirdavvkil 277 l lr +ia s ++r +k ++t + v +++af + +++ f k +++ ++f +nPivy++ + + rd +++++ FUN_002402-T2 209 LWLRPSQAIAhdpSEQGRsrvRKRVTTMVLVVSVIFAFcwITECTDYTLLVFFPKLALGNATHVISSTLVMFNSSINPIVYALISHRFRDEIIRMI 304 777665555422255555223577888888888888873245666677777888877777788899999*************************97 PP >> DUF5671 Domain of unknown function (DUF5671) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.2 3.6 1.3e+04 76 89 .. 23 36 .. 12 41 .. 0.56 2 ? 12.3 1.2 4.7e-05 0.17 55 96 .. 206 247 .. 170 279 .. 0.82 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 3.6 DUF5671 76 SvlRrwylylallv 89 Sv+ + l + lv FUN_002402-T2 23 SVIVIVALVGNSLV 36 44444444444444 PP == domain 2 score: 12.3 bits; conditional E-value: 4.7e-05 DUF5671 55 glPvwllhwrraqrrdpeerrSvlRrwylylallvaalallg 96 + +wl ++++ + +e+ rS++R+ +++ +l v+++ +++ FUN_002402-T2 206 VFTLWLRPSQAIAHDPSEQGRSRVRKRVTTMVLVVSVIFAFC 247 3335555556666666777******************99876 PP >> DUF3810 Protein of unknown function (DUF3810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.4 0.35 1.3e+03 30 74 .. 25 68 .. 13 81 .. 0.44 2 ? 11.7 1.1 4.7e-05 0.17 14 78 .. 187 248 .. 180 322 .. 0.77 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 0.35 DUF3810 30 lllillllvylvkilklkkkkkkkkkllkfllkillflsilyflF 74 +++++l+ +lv+++ ++k+ k++++ ll+++++ +++++F FUN_002402-T2 25 IVIVALVGNSLVCAI-IMKNPGKRTTMNCLLLNLAIADITVVAFF 68 333334444444444.23233333444444444433333333333 PP == domain 2 score: 11.7 bits; conditional E-value: 4.7e-05 DUF3810 14 srlfgllpfSvgdllylllillllvylvkilklkkkkkkkkkllkfllkillflsilyflFlllw 78 + l++ +p+Sv+ +ly +++ l ++ ++++ ++ ++++ k +++++l++s+ +F ++w FUN_002402-T2 187 TILIAAIPVSVMTVLYCRVVFTLWLRPSQAIAHDPSEQGRSRVRKRVTTMVLVVSV---IFAFCW 248 678999*************************5555555555555544444444444...444444 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (371 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1101 (0.0431004); expected 510.9 (0.02) Passed bias filter: 506 (0.0198082); expected 510.9 (0.02) Passed Vit filter: 30 (0.0011744); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.33u 0.39s 00:00:00.72 Elapsed: 00:00:00.42 # Mc/sec: 3600.82 // Query: FUN_002402-T3 [L=365] Description: FUN_002402 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.9e-47 160.1 13.7 1.3e-46 159.7 13.7 1.2 1 7tm_1 7 transmembrane receptor (rhodopsin family) 3e-11 43.7 12.8 5.8e-11 42.8 12.8 1.4 1 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx 5.6e-10 39.8 9.7 9.9e-10 38.9 9.7 1.4 1 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx 1.2e-09 38.4 15.2 1.7e-06 28.0 2.9 2.2 2 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw 0.00021 20.9 15.6 0.00048 19.7 15.6 1.5 1 7TM_GPCR_Srt Serpentine type 7TM GPCR chemoreceptor Srt 0.0011 19.3 11.7 0.026 14.8 11.7 2.3 1 7tm_4 Olfactory receptor ------ inclusion threshold ------ 3.8 7.3 9.0 0.12 12.2 1.6 2.0 2 DUF3810 Protein of unknown function (DUF3810) 5.9 7.0 10.2 0.22 11.6 2.5 2.3 2 Tetraspanin Tetraspanin family Domain annotation for each model (and alignments): >> 7tm_1 7 transmembrane receptor (rhodopsin family) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.7 13.7 4.1e-50 1.3e-46 1 260 [] 23 280 .. 23 280 .. 0.92 Alignments for each domain: == domain 1 score: 159.7 bits; conditional E-value: 4.1e-50 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 1 gNllVilvilrnkklrtptnifllnLavaDllvll.lvlpfalvyallegdwvfgevlCklvt..aldvvnltasillltaisiDRYlaIvkplky 93 gN lV++vil+n+ +rt++n++llnLa+aD+ v++ ++ +l++a + d +g++lCkl+t + + ++as+++++ai+i+RY a+++pl + FUN_002402-T3 23 GNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVfFASRYTLIHAYNHPDGNVGTILCKLLTggTFGWIGSCASVFTMVAIAIERYYAVTRPLGN 118 8******************************99985666777788888999**********97446899*************************** PP xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 94 krirtkrralvlilvvWvlalllslppllfsgtktesaekeetvClidfpeeestwevsytlllsvlgfllpllvilvcyvrilrtlrksakkeks 189 ++ tk +v+i + W+++++l+lp +l +k+++ ++ + C+ ++p ++++ y ll++vl +p++v++v+y+r++ tl+ +++++ FUN_002402-T3 119 RATFTKDSLKVIISASWIFGIILCLPDFL---VKDFC--ESYRACVGNWPPAHAWMPKAYSLLWTVLLTAIPVSVMTVLYSRVILTLWVKPSRAIG 209 ***************************99...56787..789*********9889*********************************99999877 PP xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF 7tm_1 190 kkkksarker...kalktllvvvvvfvlcwlPyfilllldsllkeceseklvetallitlllayvnsclNPiiY 260 ++ +++ ++r ++++++lvv ++f++cw+ + +l ++ ++ l ++ i++ l+++ns +NPi+Y FUN_002402-T3 210 NDPSEQGRSRvrkRVTTMVLVVSIIFAFCWITESTDYILLMF---FPKLALGNATHVISSTLIMFNSSINPIVY 280 4444444444444**************************999...9999999*********************9 PP >> 7TM_GPCR_Srsx Serpentine type 7TM GPCR chemoreceptor Srsx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.8 12.8 1.8e-14 5.8e-11 2 256 .. 18 294 .. 17 295 .. 0.77 Alignments for each domain: == domain 1 score: 42.8 bits; conditional E-value: 1.8e-14 7TM_GPCR_Srsx 2 vvGliGNvllilltfkkkkLrskssiLicvqcladllclvgelvfvvlllt.....gtqlkreeCFlli..ivyvfgltaqsvllLvigiDlliav 90 vv l+GN+l+ +++k++ +r+ +++L+ +++ad+ ++v+ ++ + l++ + ++ C ll ++ +g +a+ +++i+i + +av FUN_002402-T3 18 VVALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVFF-ASRYTLIHaynhpDGNVGTILCKLLTggTFGWIGSCASVFTMVAIAIERYYAV 112 899********************************9776653.33333333000113344455686654447999********************* PP 7TM_GPCR_Srsx 91 kfPirYrllskekYllillifpvlyssiilvlgflqrdde.tiivCa....pplalagkas.eiftlssliinvivllv.ylvliiilkkkkek.. 177 + P+ r ++ l + + ++ +i+ + +fl+ d +C p a +ka+ ++t++ +i v+v+ v y +i++l k ++ FUN_002402-T3 113 TRPLGNRATFTKDSLKVIISASWIFGIILCLPDFLVKDFCeSYRACVgnwpPAHAWMPKAYsLLWTVLLTAIPVSVMTVlYSRVILTLWVKPSRai 208 *********9999***********************9975477778544434455556665378*********99986626666666666655578 PP 7TM_GPCR_Srsx 178 ....kkssskkvlkslkvtv....vififgWftstilntvllalteseevekliqayagilvllsfsqnffVtywrsseYrkafrel 256 +++ ++v k+++++v +if f+W+t ++ ++l+ + + ++ + ++ ++l+++++s n +V+ ++s+++r++++++ FUN_002402-T3 209 gndpSEQGRSRVRKRVTTMVlvvsIIFAFCWITESTDYILLM-FFPKLALGNATHVISSTLIMFNSSINPIVYALISHRFRDEVIRM 294 8888666666677776666633336899***98887776666.66677888899999**************************9987 PP >> 7TM_GPCR_Srx Serpentine type 7TM GPCR chemoreceptor Srx # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.9 9.7 3.1e-13 9.9e-10 6 228 .. 19 247 .. 15 276 .. 0.71 Alignments for each domain: == domain 1 score: 38.9 bits; conditional E-value: 3.1e-13 7TM_GPCR_Srx 6 iGlvlNllvliailklkslknsFgilclskaisnaiilliflfyvvPmtllqsell...kellnshliglialglYeisplsqllialNRfcavff 98 + lv N+lv +ilk+ +++ ++l l+ ai++++++++f+ ++ + + +++ + + l++ ++g+++++ ++s ++ + ia++R +av FUN_002402-T3 19 VALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVFFASRYTLIHAYNHPDGnvgTILCKLLTGGTFGWIGSCASVFTMVAIAIERYYAVTR 114 55788*********************************99999999999988887755566777789***************************** PP 7TM_GPCR_Srx 99 plkyekifsiknTkiiiviiwivslifitvlylpegCkllynpetltwsfee..teccktiswyldfllililviitlvlnlltaikli..lskkk 190 pl f++ + k+ii+++wi+ +i ++ +l+++ +y + + +w + + ++++ w + +l+ + + ++t++ ++++ + ++ FUN_002402-T3 115 PLGNRATFTKDSLKVIISASWIFGIILCLPDFLVKDFCESYRACVGNWPPAHawMPKAYSLLWTV-LLTAIPVSVMTVLYSRVILTLWVkpSRAIG 209 *****************************999999888899*******77653345555555555.444444444444444444444442222222 PP 7TM_GPCR_Srx 191 skstsseeskrrrkreinffkQsvlQdllflidlvnyf 228 + +++ s+ r++ +++ ++ s++ +++ +++++ y+ FUN_002402-T3 210 NDPSEQGRSRVRKRVTTMVLVVSIIFAFCWITESTDYI 247 22233333444444455555556655555555444443 PP >> 7TM_GPCR_Srw Serpentine type 7TM GPCR chemoreceptor Srw # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 4.6 2.3e-06 0.0073 2 136 .. 12 141 .. 11 158 .. 0.72 2 ! 28.0 2.9 5.4e-10 1.7e-06 192 318 .. 173 297 .. 165 298 .. 0.85 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 2.3e-06 7TM_GPCR_Srw 2 vefilsivgviinifHli.iLtrksmrtssinilmiGIaicDiltmlltiynkileliieleeseClppdsylkvlldlileslkdvsrrcstwlg 96 v+ ++ +v+++ n + + iL ++ mrt ++n+l+ ai+Di +++ +++ li+ +++ + + + k+l+ ++ + + +s++ + FUN_002402-T3 12 VQSVIVVVALVGNSLVCAvILKNRGMRT-TMNVLLLNLAIADITVVVFFASRYT--LIHAYNHPDGNVGTILCKLLTGG---TFGWIGSCASVFTM 101 5677888888888766650555666666.78************99999888887..77777666665555555555555...55555566699*** PP 7TM_GPCR_Srw 97 vlmAliRtlvvknplsnkiqklskpkfglliilivlllsl 136 v++A+ R+ v+ pl n++ + ++ +++ ++l FUN_002402-T3 102 VAIAIERYYAVTRPLGNRATFTKDSLKVIISASWIFGIIL 141 ******************9866555555555555555444 PP == domain 2 score: 28.0 bits; conditional E-value: 5.4e-10 7TM_GPCR_Srw 192 fllidgilskiipsillpiltilLiieLrkakksrkkls..kskkneksdkttkLVlfmTisffiaelplGiiyivkfifskssgirsileelevi 285 + l+ +l++ ip ++ +l i L+ ++ ++ +++ +++ t +Vl+++i+f + + yi+ ++f k + + vi FUN_002402-T3 173 YSLLWTVLLTAIPVSVMTVLYSRVILTLWVKPSRAIGNDpsEQGRSRVRKRVTTMVLVVSIIFAFCWITESTDYILLMFFPK----LALGNATHVI 264 55555666788888888888888888888776666666642344778999******************************99....67999999** PP 7TM_GPCR_Srw 286 fsllltinsisHflicllmSsqYRktvkklfgc 318 s+l+++ns++ +++ l+S++ R+ v++++++ FUN_002402-T3 265 SSTLIMFNSSINPIVYALISHRFRDEVIRMIRV 297 ******************************986 PP >> 7TM_GPCR_Srt Serpentine type 7TM GPCR chemoreceptor Srt # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 15.6 1.5e-07 0.00048 43 310 .. 18 301 .. 3 304 .. 0.74 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 1.5e-07 7TM_GPCR_Srt 43 ivlllLYipillvilkkkliksscykimllLailDilall.vnsiitGilaiq......GavfCsyPtliyiaGaiglglWmssclasilLavnRv 131 +v l+ +++ vilk+ ++++ ++l Lai Di+ ++ + s t i a++ G+ C+ + + G++g ++s ++ + +a++R FUN_002402-T3 18 VVALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVfFASRYTLIHAYNhpdgnvGTILCK----LLTGGTFGWIGSCASVFTMVAIAIERY 109 333334678899************************87651566666555543222222455554....24455555444444445677889**** PP 7TM_GPCR_Srt 132 lelnkkellkvlFekkktyivllllivYgiyallftkpvi.FsskylswffdPlifegkdkelYkniphtvnNllvvvlttllYlylcvllikklk 226 ++ + + F+k ++ +++ +++++gi +l v F +y + + + + ++ Y+ +++++ ++ v+++t+lY ++++l k + FUN_002402-T3 110 YAVTRPLGNRATFTKDSLKVIISASWIFGIILCLPDFLVKdFCESYRACVGNWPPAHAWMPKAYSLLWTVLLTAIPVSVMTVLYSRVILTLWVKPS 205 *****************************9988633322136666666665533335888899*********************988888877654 PP 7TM_GPCR_Srt 227 ks.........tssklskakrqillQsvllcvfnavaaliYvymqfiev...pelliligqllWqlssgcvaiiYltlNrtiRnevlkllllkkir 310 + +s ++ + +l+ s++++++ + ++ Y +++f+ ++ +i+ l ++s i+Y + + R+ev++++ + ++r FUN_002402-T3 206 RAigndpseqgRSRVRKRVTTMVLVVSIIFAFCWITESTDYILLMFFPKlalGNATHVISSTLIMFNSSINPIVYALISHRFRDEVIRMIRVTRTR 301 433333323234445566778899*********************9964222677889999999**************************987766 PP >> 7tm_4 Olfactory receptor # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 11.7 8e-06 0.026 2 277 .. 14 295 .. 13 297 .. 0.73 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 8e-06 7tm_4 2 clvyliillGnltilfvikteaslhqPmylflallalidlglsastlPtvlGiflvdareisfeacllqlffihkfsllesa....vllamavdrf 93 +++ +++l+Gn+ + vi ++ + m ++l la++d+ + + + i + + + l +l+ +f + s+ +++a+a++r+ FUN_002402-T3 14 SVIVVVALVGNSLVCAVILKNRGMRTTMNVLLLNLAIADITVVVFFASRYTLIHAYNHPDGNVGTILCKLLTGGTFGWIGSCasvfTMVAIAIERY 109 57889*************************************99999998889999999999999999999888887766541212467889**** PP 7tm_4 94 vaiysplryteiltnkvisriglvvlvrsvilvlplifllrrlkfcgsevlshsyclhaelaklscadikvnniyGlfvvvstlgldsllivlsyg 189 a+ +pl + +t+ + +i ++ +il lp fl++ + + ++ + + + + + + + + v v t +l s +i+ ++ FUN_002402-T3 110 YAVTRPLGNRATFTKDSLKVIISASWIFGIILCLP-DFLVKDFCESYRACVG-NWPPAHAWMPKAYSLLWTVLLTAIPVSVMT-VLYSRVILTLWV 202 ******************************99999.4666654332223332.233333333333333333444444444444.455666777788 PP 7tm_4 190 lilrtvlgiasreer...kkalntcgshvcavlafy..vPmiglsvvhrfgkkvsrllqvllanlyllfPPvlnPivysvktkeirdavvkil 277 + r++ + +s ++r +k ++t + v +++af + ++ f k +++ ++f +nPivy++ + + rd v++++ FUN_002402-T3 203 KPSRAIGNDPSEQGRsrvRKRVTTMVLVVSIIFAFCwiTESTDYILLMFFPKLALGNATHVISSTLIMFNSSINPIVYALISHRFRDEVIRMI 295 8889998889988883234566666666666666632134444445555666555566778899999************************97 PP >> DUF3810 Protein of unknown function (DUF3810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 1.0 0.48 1.5e+03 29 75 .. 15 60 .. 3 71 .. 0.56 2 ? 12.2 1.6 3.9e-05 0.12 13 78 .. 177 242 .. 169 279 .. 0.71 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.48 DUF3810 29 ylllillllvylvkilklkkkkkkkkkllkfllkillflsilyflFl 75 ++++++l+ +lv+++ + k++ ++++ ll+++++ +++++F FUN_002402-T3 15 VIVVVALVGNSLVCAV-ILKNRGMRTTMNVLLLNLAIADITVVVFFA 60 2334444444555555.444555556666666666665555555554 PP == domain 2 score: 12.2 bits; conditional E-value: 3.9e-05 DUF3810 13 lsrlfgllpfSvgdllylllillllvylvkilklkkkkkkkkkllkfllkillflsilyflFlllw 78 + l+ +p+Sv+ +ly +il l v+ +++ ++ ++++ k +++++l++si++++ ++ FUN_002402-T3 177 WTVLLTAIPVSVMTVLYSRVILTLWVKPSRAIGNDPSEQGRSRVRKRVTTMVLVVSIIFAFCWITE 242 5678899*************************5555555555555555555555555554444444 PP >> Tetraspanin Tetraspanin family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 2.5 7e-05 0.22 48 98 .. 7 60 .. 2 78 .. 0.88 2 ? -0.3 0.2 0.32 1e+03 56 80 .. 228 252 .. 171 293 .. 0.60 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 7e-05 xxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 48 vllivlGaviflvgflG...ccgalkesrcllllyfvlllllflaelaagilaf 98 +i++ +vi++v+++G +c+++ ++r + ++ +vlll l +a +++++++ FUN_002402-T3 7 KAVIAVQSVIVVVALVGnslVCAVILKNRGMRTTMNVLLLNLAIADITVVVFFA 60 56899999***************************************9888654 PP == domain 2 score: -0.3 bits; conditional E-value: 0.32 xxxxxxxxxxxxxxxxxxxxxxxxx RF Tetraspanin 56 viflvgflGccgalkesrcllllyf 80 v+++ ++ +c++ +ll++f FUN_002402-T3 228 VLVVSIIFAFCWITESTDYILLMFF 252 2222223444444444445555555 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (365 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1012 (0.0396164); expected 510.9 (0.02) Passed bias filter: 398 (0.0155803); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 8 (0.000313173); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.36u 0.40s 00:00:00.76 Elapsed: 00:00:00.42 # Mc/sec: 3501.30 // Query: FUN_002403-T1 [L=100] Description: FUN_002403 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0087 16.9 0.4 0.0097 16.8 0.4 1.1 1 OVT1 Major antigen, helical domain Domain annotation for each model (and alignments): >> OVT1 Major antigen, helical domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.4 3.8e-07 0.0097 28 95 .. 14 83 .. 4 88 .. 0.85 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 3.8e-07 OVT1 28 eelkrkllkdlenqrarldavtseldklqtey..esatkntvaieqtvkElkqqrDeiskqkdelsrqLf 95 ++k ++ ++e+qr r ++ se++k+ +++ ++++++ + + + E k+qr+e + + d s ++ FUN_002403-T1 14 SSTKGDISAEIEEQRFRTPITASECEKFDKSLvsDASHRKWAWVLKVFEERKKQRNEAVLKEDYYSESII 83 57899***********************99853377888999999999*********9998888877665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 877 (0.0343316); expected 510.9 (0.02) Passed bias filter: 533 (0.0208651); expected 510.9 (0.02) Passed Vit filter: 40 (0.00156586); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.28u 0.37s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1011.93 // Query: FUN_002404-T1 [L=1479] Description: FUN_002404 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-52 179.5 10.1 1.5e-52 179.5 10.1 2.3 2 GCP_C_terminal Gamma tubulin complex component C-terminal 3.2e-40 139.0 2.4 3.5e-40 138.9 0.2 2.2 3 GCP_N_terminal Gamma tubulin complex component N-terminal 9e-32 110.9 0.3 1.7e-31 109.9 0.3 1.5 1 GCP6_N Gamma-tubulin complex component 6 N-terminus ------ inclusion threshold ------ 0.14 12.9 0.4 0.8 10.5 0.1 2.6 2 GCP5-Mod21_C Gamma-Tubulin ring complex non-core subunit m Domain annotation for each model (and alignments): >> GCP_C_terminal Gamma tubulin complex component C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 3.3 0.44 2.8e+03 184 251 .. 417 496 .. 396 549 .. 0.55 2 ! 179.5 10.1 2.3e-56 1.5e-52 3 309 .] 1164 1466 .. 1163 1466 .. 0.86 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 0.44 GCP_C_terminal 184 eeklkkkasdldelieaHekfLdrilkkllLtkkqekllklleeilelilkFaealdrlylslsesa...............e 251 ++++ ++ l++ e +k +++ ++ lL+++ ++ k l ei eli k ++a++ +++++++ + FUN_002404-T1 417 VGTIQEMRNRLKQQKEDERKAIENERQRGLLEER-KRTEKALAEITELIQKAKDAVEV--KKREDLKmlkeqmedalknkalA 496 4444333444555555555566666666666555.55556666666666666666555..33333323333333333333330 PP == domain 2 score: 179.5 bits; conditional E-value: 2.3e-56 GCP_C_terminal 3 dhLkalkrylLLgqGdFisrLmealfdel...wkpasselrlnLtslLeealrssnaeqsdelkddlsfal.dlpevleeldarlepdslggl 91 +h+++ k+ l++++G+F+ L+++lf++l p + L+++ +al+ss ++ +e+ +++ fal lp+++ +++++g l FUN_002404-T1 1164 KHFNLFKKLLFMEDGEFSLSLSNQLFEKLtsgISPRDMCSATVLNGIVGKALQSSVYSEITEHAQHIAFALkTLPDIF-------KQNEMGTL 1249 6****************************77645555666777**********9976666777888888886666644.......4456789* PP GCP_C_terminal 92 dfltLeYkvpwplslvltpealekYqrlfrfLlrlkrvefalssvw........kkrkakssrsvllkkarllraemlhfvsqlqyYvlfevi 176 dfl L Y+v+wpl++v+t++++ kY+++f+f+lrlkr++ +l +vw +++ a+ s++l++++l+r+em+hfv++l+ Y+ ++++ FUN_002404-T1 1250 DFLELRYTVEWPLNIVITEKSIVKYNKIFSFMLRLKRLSWVLRDVWfhlkyiafSRDAAM---SPQLRQLQLFRHEMQHFVHNLEGYLSNQIL 1339 **********************************************97655442222222...33499************************* PP GCP_C_terminal 177 epsWkeleeklkkkasdldelieaHekfLdrilkkllLtkkqekllklleeilelilkFaealdrlylslsesaeeeeeeeleeeleerlkel 269 +++W+e++e l+ ++s+ld+l ++H+++L + +++ lL++k +++++++++ +lilk++ +l + ++++ ++ ++++ + + + + FUN_002404-T1 1340 NVTWSEFQEGLT-NVSSLDDLHNQHTEYLRKAIFRSLLNNKAAPVMTIISDMGKLILKLRTQLLASPWQQDP-----NTGHVSHPTFDVMFNT 1426 ***********6.5666******************************************9866552244333.....56778886678888** PP GCP_C_terminal 270 ekkFrkkvsellkvlralkeskdeedlrqLllrLdfneyY 309 +k F++ ++l++v+++l ++ ++ +++llr++fn++Y FUN_002404-T1 1427 HKAFKEYSRFLFTVVSKLVQRGYQSYWADFLLRINFNDFY 1466 *****************97777889**************9 PP >> GCP_N_terminal Gamma tubulin complex component N-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.9 0.2 5.5e-44 3.5e-40 1 282 [. 128 423 .. 128 472 .. 0.83 2 ? -3.3 0.0 1.1 7e+03 68 91 .. 1208 1231 .. 1188 1253 .. 0.86 3 ? -2.3 0.1 0.55 3.5e+03 64 174 .. 1344 1386 .. 1308 1400 .. 0.59 Alignments for each domain: == domain 1 score: 138.9 bits; conditional E-value: 5.5e-44 GCP_N_terminal 1 lrdllfllqGisgkyirfdesds..rivkdlripsvlppslrellsellelgtlyrrlrkfveeksssesglvlqalcaalqeeLteyyrliaql 93 + d + +l+G+++k++ fd+++ +++k++r+++++p+ l+++l +l+ +gt y +l+kf+ ++ + glvlqa+ a+q+ L+ y++++ ++ FUN_002404-T1 128 INDAINVLIGVPSKTFLFDKQTFsfHVSKHIRLSGTSPEMLSNVLARLSAMGTEYIQLNKFATHHRGQAAGLVLQAFLGAVQNYLHCYRATVLSV 222 67999************99955489********************************************************************** PP GCP_N_terminal 94 esqlleaskeiltLkrlvvwlqealerlrllsnlveeve.......kqnl.....kggallsllhe.atshGdpfvrellerlleevskpyleml 175 ++ +++ ++l + +++ ++lr+l+n++ e + g +ll++l++ +h++++ + +l +ll++ ++py + + FUN_002404-T1 223 DAPSVQSP------LQLSFAFEKLAKQLRFLANVCMCSEafkrapdD--PrvkfpAGVKLLTYLYQlCLEHSSSQFYPILLSLLRHSVMPYIAFV 309 ***99977......789999999999999999999877744455551..0555558**********7777************************* PP GCP_N_terminal 176 ekWileGeldDpynEFFveeneeeakeelteesssdlweekYelr....kemlPsflspelaekIlstGKslnflrescgdsew.........ve 257 ++W+++G+ +D ++EF++e +e+ ++++w + Y++ + +P fl + la+ I+ +GK++n+l+ +c + +e FUN_002404-T1 310 QTWVFKGVCNDMFGEFMIETDEQFLAY-----RDKHFWTQGYIMTgrdkLDCVPLFLGE-LADDIFVCGKTINLLKLCCPEHLLcdpgirlptME 398 ******************998888654.....7899******9998887788*******.******************88844335554433333 PP GCP_N_terminal 258 etas..eleygdslss.slsleelIdsa 282 t+s +l+ ++ + ++++ I++ FUN_002404-T1 399 VTFSmkRLSKIE---EeCKQYVGTIQEM 423 333333333333...1235555555544 PP == domain 2 score: -3.3 bits; conditional E-value: 1.1 GCP_N_terminal 68 sglvlqalcaalqeeLteyyrlia 91 +g v++al++++ e+te+ + ia FUN_002404-T1 1208 NGIVGKALQSSVYSEITEHAQHIA 1231 789999999999999999999887 PP == domain 3 score: -2.3 bits; conditional E-value: 0.55 GCP_N_terminal 64 sssesglvlqalcaalqeeLteyyrliaqlesqlleaskeiltLkrlvvwlqealerlrllsnlveevekqnlkggallsllhe.atshGdpf 155 s+++ gl +s+l + + +h + FUN_002404-T1 1344 SEFQEGL---------------------------------------------------------------------TNVSSLDDlHNQHTEYL 1367 3344444.....................................................................44455555444555555 PP GCP_N_terminal 156 vrellerlleevskpylem 174 ++++++ll++ ++p +++ FUN_002404-T1 1368 RKAIFRSLLNNKAAPVMTI 1386 5555555555555555555 PP >> GCP6_N Gamma-tubulin complex component 6 N-terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.9 0.3 2.7e-35 1.7e-31 199 315 .] 1 115 [. 1 115 [. 0.89 Alignments for each domain: == domain 1 score: 109.9 bits; conditional E-value: 2.7e-35 GCP6_N 199 ldvrLdLPpvPsnadlsglaikvpesldqseDEGFqsasnltpdsq...sep.sk.tpdvdvWeaaltyepskrrcWErvGcppgkkEepYlTEaG 289 ++v+L LP++Ps+ +++l + + e+++++eDEGF+s +++++s+ s++ s+ + ++d+W+aal++++++ ++WE+ G+++ kE+pYl EaG FUN_002404-T1 1 MQVKLSLPQLPSD--SNTLHSLATEQRESAEDEGFESL-ETSSNSSfssSDQaSVlHDNMDIWSAALKLPSQRCYTWEMNGRREMLKEKPYLSEAG 93 9***********9..99*******************98.66666655433331332578************************************* PP GCP6_N 290 reaFDklyrllegelrvlssallqlP 315 + +FD++y+++ +++ s+l+++P FUN_002404-T1 94 PVVFDAMYDTVMRQV----SYLVKSP 115 ***************....9999988 PP >> GCP5-Mod21_C Gamma-Tubulin ring complex non-core subunit mod21, C-terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.1 0.00012 0.8 6 68 .. 126 188 .. 121 189 .. 0.88 2 ? -2.9 0.0 2 1.3e+04 27 50 .. 468 489 .. 463 492 .. 0.78 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00012 GCP5-Mod21_C 6 siireviymLlGlpsslFlrrgskvEvrlsllpkiqhlsqealrsiLsefadyGselailrrl 68 +i + i L+G ps Fl +++ s+ + + s e+l+ +L + +G e l+++ FUN_002404-T1 126 TLINDAINVLIGVPSKTFLFDKQTFSFHVSKHIRLSGTSPEMLSNVLARLSAMGTEYIQLNKF 188 6899***********999888999999999999*********************997777765 PP == domain 2 score: -2.9 bits; conditional E-value: 2 GCP5-Mod21_C 27 gskvEvrlsllpkiqhlsqealrs 50 ++ vEv+ + +++l +++ ++ FUN_002404-T1 468 KDAVEVKKRE--DLKMLKEQMEDA 489 6778888887..999999999776 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1479 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 2253 (0.0881973); expected 510.9 (0.02) Passed bias filter: 651 (0.0254844); expected 510.9 (0.02) Passed Vit filter: 64 (0.00250538); expected 25.5 (0.001) Passed Fwd filter: 11 (0.000430613); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.55u 0.38s 00:00:00.93 Elapsed: 00:00:00.42 # Mc/sec: 14209.75 // Query: FUN_002405-T1 [L=454] Description: FUN_002405 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.7e-95 320.3 0.0 3.2e-95 320.1 0.0 1.0 1 p450 Cytochrome P450 Domain annotation for each model (and alignments): >> p450 Cytochrome P450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 320.1 0.0 1.2e-99 3.2e-95 1 432 [. 13 443 .. 13 452 .. 0.94 Alignments for each domain: == domain 1 score: 320.1 bits; conditional E-value: 1.2e-99 p450 1 Ppgptplplvgnllqlekkeelhsvltklqkkygpifrlklgskpvvvlsgpelvkevlikkgeefsgrpdealletlskafkgkgvlfang.ekw 95 Ppgp +lp++gn+ ++ + ++t+++k yg++fr++lg++ +vv+s +++ke+l++k+ +f+grp + +s k v+ ++ ++ FUN_002405-T1 13 PPGPFALPIFGNAYLMAC-PSRYINFTEMEKDYGEVFRIYLGTQLAVVIS-GDAIKEALVTKAVDFAGRPSLYSADVFSHDRKAPSVAIEDYsQRL 106 999*************96.566777*******************999999.79********************9999999**************** PP p450 96 rklRrlltptltsfgkl.sleeiveeeardlveklrkkagesselditellskaalnvicsilFgerfdlledekfsellkaveelsellssssvq 190 + lR ++ +tl +f + +i+ + ++l++++++k ge+ d+te + + + ++ c+ Fg+r + +d++ ++l+++ e++++l + + FUN_002405-T1 107 KHLRDISFATLKFF-TPdQQASIISDKLDRLIQNIHSKLGEP--QDVTEQILQTVGSAFCTMSFGSRNE-EDDPELKKLIEVDSEIFTMLTNGF-- 196 **************.434689*********************..9**********************88.********************8888.. PP p450 191 lldlfpllkylptkllkklkeavkklkdlldklieerretldsakkkrrdfldalllak.....kekkge.sklsdeelkatvlellfaGvdTtss 280 ++dlfp+lk +p+ + l+e +k+++++l k+ +e+ ++ + ++ d++d++l+ak k +++e +l+++ +++ + ++++a+++ + FUN_002405-T1 197 AVDLFPWLKHFPSTSIRSLRELCKERDEILGKIYHEHVQSNIVE--NPEDMTDVILKAKkeaedKGSSNEgVQLTQDRITMFMNDIFIASMNNITY 290 ********************************************..9************8765433334489************************ PP p450 281 tlswaLyeLaknPevqeklreEidevlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtlvivnlyalhrdpkv 376 +swaL++L+++Pevq l+eE+++v+g +r p+++d + l++l+a+i Et+Rl++++p+ +pR++t d++++gy+ipk+t+v+ n+++lh++ ++ FUN_002405-T1 291 IVSWALLYLIHYPEVQTTLQEELERVIGPNRLPELKDQECLHFLKATITETQRLSSHLPFVVPRKTTVDTTLQGYFIPKDTTVFANVWSLHHNLDI 386 ************************************************************************************************ PP p450 377 fpnPeeFdpeRFldekgnsrksf..aflPFGaGpRnClGerlArmelklflatlLqnF 432 +++Pe F+p+RFld++g++++++ f PFG GpR C G +A+m++ +l +lL ++ FUN_002405-T1 387 WEDPEDFKPQRFLDKDGTFVPPDegHFAPFGLGPRYCTGASMAKMMML-LLDNLLARY 443 *****************8766652269******************985.566666665 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (454 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 708 (0.0277158); expected 510.9 (0.02) Passed bias filter: 643 (0.0251713); expected 510.9 (0.02) Passed Vit filter: 48 (0.00187904); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.40s 00:00:00.75 Elapsed: 00:00:00.42 # Mc/sec: 4390.46 // Query: FUN_002406-T1 [L=288] Description: FUN_002406 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-38 130.7 10.1 8.2e-38 130.1 10.1 1.2 1 STIMATE STIMATE family ------ inclusion threshold ------ 0.044 14.0 0.1 0.073 13.3 0.1 1.3 1 DUF3332 Domain of unknown function (DUF3332) 0.12 12.7 0.1 0.22 11.8 0.1 1.4 1 TMEM154 TMEM154 protein family 0.33 11.6 4.7 0.2 12.3 1.2 2.1 2 DUF7420 Family of unknown function (DUF7420) 3 8.6 10.7 9.8 7.0 3.8 2.2 2 YrvL Regulatory protein YrvL Domain annotation for each model (and alignments): >> STIMATE STIMATE family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.1 10.1 1.6e-41 8.2e-38 1 123 [. 106 227 .. 106 228 .. 0.98 Alignments for each domain: == domain 1 score: 130.1 bits; conditional E-value: 1.6e-41 STIMATE 1 CswYllnlllDttlGvlilylllkllekllkklkleslesGeYgkpskvsawlkQllvyllilvlmKlvvllllllfeelekvgellLswleenpk 96 C+wYl+n+llD+t+G++++yl l++++ +++ ++++sl++GeYg+p++++aw+ Q+l+yl++++++K +++ll++l + + +v++++L +++++pk FUN_002406-T1 106 CTWYLINFLLDSTVGLVVIYLSLQFMQVVVRMYQWDSLRFGEYGNPPQCKAWAGQCLLYLCAVIVEKATITLLVQLEF-WVDVRKFILLPVKNHPK 200 *********************************************978**************************9977.99*************** PP STIMATE 97 lqlvlvmliiPlilNalqfwiiDsilk 123 ++l++vml+iP+++Na++fw++D++l+ FUN_002406-T1 201 VELFIVMLVIPFVFNAIMFWVVDNFLM 227 **************************8 PP >> DUF3332 Domain of unknown function (DUF3332) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.1 1.4e-05 0.073 57 114 .. 205 260 .. 199 279 .. 0.79 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 1.4e-05 DUF3332 57 iaalaDllifNsIEFWsGkNPiaekvgeiekvkgeldgeeykvektkngytiekeden 114 i +l+ ++fN I FW +N + k+++ ++ ++ ++ +kv+++k + ++ de+ FUN_002406-T1 205 IVMLVIPFVFNAIMFWVVDNFLMRKKKKLFQKEDTRNKV-SKVKYEK-RSVMNGSDEE 260 55666679****************999999999996666.7899888.4445555554 PP >> TMEM154 TMEM154 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 4.3e-05 0.22 63 104 .. 204 246 .. 195 260 .. 0.85 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 4.3e-05 TMEM154 63 filmviiPlvlliilllvv.vilitkykrkRaKddekseaesd 104 fi+m++iP v +i++ vv +l++k+k+ +K+d+++++++ FUN_002406-T1 204 FIVMLVIPFVFNAIMFWVVdNFLMRKKKKLFQKEDTRNKVSKV 246 89**********9999888469999999999999999998865 PP >> DUF7420 Family of unknown function (DUF7420) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.1 0.36 1.9e+03 49 73 .. 111 135 .. 101 140 .. 0.60 2 ? 12.3 1.2 3.9e-05 0.2 46 118 .. 163 240 .. 158 245 .. 0.87 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 0.36 DUF7420 49 vaalvevlvvtllvyllfsalnvnv 73 +++l +v +++yl++++++v v FUN_002406-T1 111 INFLLDSTVGLVVIYLSLQFMQVVV 135 5555555555555566666665544 PP == domain 2 score: 12.3 bits; conditional E-value: 3.9e-05 DUF7420 46 tvivaalvevlvvtllvyllf.....salnvnvnlltvvaaflvvyllrniaaYlvawgvwsifvrierkkmkkelee 118 ++a++ve +++tllv l f +++ ++v+ + v f+v+ ++ ++ ++ w+v + r+++k ++ke ++ FUN_002406-T1 163 LYLCAVIVEKATITLLVQLEFwvdvrKFILLPVKNHPKVELFIVMLVIPFVFNAIMFWVVDNFLMRKKKKLFQKEDTR 240 567999***********9977555557899**************************************9999998665 PP >> YrvL Regulatory protein YrvL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.7 0.6 0.0048 24 49 102 .. 83 134 .. 70 144 .. 0.77 2 ? 7.0 3.8 0.0019 9.8 51 99 .. 177 226 .. 160 229 .. 0.86 Alignments for each domain: == domain 1 score: 5.7 bits; conditional E-value: 0.0048 YrvL 49 fvlgllielllkilskillvkklskslllllafiiellftlltihliDelmdsv 102 ++g+l+ +++i+ +ll + l+ f+++ ++ l++i+l ++m+ v FUN_002406-T1 83 QAVGALLVHFANIFLASLL--RGDPCTWYLINFLLDSTVGLVVIYLSLQFMQVV 134 5688888889999999998..44455556889*******************976 PP == domain 2 score: 7.0 bits; conditional E-value: 0.0019 YrvL 51 lgllielllkilskill.vkklskslllllafiiellftlltihliDelm 99 l + +e+ + + ++ill vk+ +k l+++ ++i ++f+ + ++D+++ FUN_002406-T1 177 LLVQLEFWVDVRKFILLpVKNHPKVELFIVMLVIPFVFNAIMFWVVDNFL 226 344688899999999999*****************************996 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (288 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 990 (0.0387551); expected 510.9 (0.02) Passed bias filter: 527 (0.0206303); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 5 (0.000195733); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.31u 0.40s 00:00:00.71 Elapsed: 00:00:00.41 # Mc/sec: 2804.87 // Query: FUN_002407-T1 [L=134] Description: FUN_002407 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00037 21.1 0.0 0.00058 20.5 0.0 1.4 1 Peptidase_C1 Papain family cysteine protease Domain annotation for each model (and alignments): >> Peptidase_C1 Papain family cysteine protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 2.3e-08 0.00058 154 207 .. 33 91 .. 1 102 [. 0.62 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 2.3e-08 Peptidase_C1 154 G...vyket.....ecsk.telnhavllvGygtengkdyWivkNsWgtdwgekGYiriargkn 207 v++ + +cs+ hav+ y+ + + + NsWg++w ++G++r++++ + FUN_002407-T1 33 NsrrVLTRSyldsrRCSTsAPRGHAVVPTSYDAD----SFRLMNSWGDTWADHGFFRVQKSLS 91 3444333333333466665567888888888876....68899***************99866 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (134 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 523 (0.0204737); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.22u 0.43s 00:00:00.65 Elapsed: 00:00:00.39 # Mc/sec: 1383.67 // Query: FUN_002408-T1 [L=1317] Description: FUN_002408 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-65 222.7 0.0 2.3e-65 221.5 0.0 1.6 1 GT4-conflict Family 4 Glycosyltransferase in conflict sys 4e-21 75.8 0.0 2.6e-20 73.2 0.1 2.3 2 Glycos_transf_1 Glycosyl transferases group 1 1.7e-18 67.8 0.1 5.6e-16 59.6 0.0 4.0 3 Glyco_trans_1_4 Glycosyl transferases group 1 0.00075 19.3 0.0 20 4.9 0.0 4.3 4 CCB2_CCB4 Cofactor assembly of complex C subunit B, CC 0.0013 18.4 2.4 49 3.5 0.0 5.0 5 KPBB_C Phosphorylase b kinase C-terminal domain 0.0025 18.9 0.1 1.1 10.3 0.0 3.7 2 VWA_2 von Willebrand factor type A domain 0.0093 16.9 0.4 72 4.4 0.0 4.1 4 DUF7185 Family of unknown function (DUF7185) ------ inclusion threshold ------ 0.01 17.2 4.5 19 6.7 0.1 4.6 4 Pup Pup-like protein 0.011 15.6 0.0 2.8 7.8 0.0 3.3 3 UTP20 U3 small nucleolar RNA-associated protein 20 0.019 15.4 0.4 41 4.6 0.0 4.3 4 DUF6990 Family of unknown function (DUF6990) 0.066 13.2 0.4 92 3.0 0.0 4.0 4 PanZ Acetyltransferase (GNAT) domain, PanZ 0.077 13.2 0.0 12 6.2 0.0 3.8 3 VapC50_C VapC50 C-terminal domain 0.13 13.2 1.4 1.2e+02 3.6 0.0 3.9 3 FlgN FlgN protein 0.99 10.0 8.2 17 6.1 0.2 4.1 4 UPF0367 UPF0367 protein family Domain annotation for each model (and alignments): >> GT4-conflict Family 4 Glycosyltransferase in conflict systems # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 221.5 0.0 1.3e-68 2.3e-65 40 385 .] 7 338 .. 2 338 .. 0.91 Alignments for each domain: == domain 1 score: 221.5 bits; conditional E-value: 1.3e-68 GT4-conflict 40 seeeiadAkaagVrLvkaeaepgvsereslllrrpelpagvepdlviGHgrvtGpaAkalaedfypdakrvhfvHmapdelewlkekrdaaeraee 135 see++++A+ +V L+ka+++pg l++ p+ + d+viGHg G+ ++e pd+k +++vH++p+el+++k+ +++ ++++ FUN_002408-T1 7 SEEDERAAAGFRVCLLKAKKKPGYDPID-WLASVPK---DHHMDVVIGHGIRLGRQVLTIKEIC-PDCKWIQVVHTDPEELAMFKDYAGPTVKGAK 97 67888889999************99998.5566554...5567*******************99.********************999******** PP GT4-conflict 136 rekierelaakAdlvvaVGprLaeearrllseapgepkvleldpgfdveaeeeprtppeggklkvLllGRae..DaelKgldlAaravgrlakesr 229 +++ e+el++ Ad vvaVGp+L+e + l+++ + ++v++l+pg+ e+++ +++++e+++++vL++GR + D +Kg+d+A rav+ l + + FUN_002408-T1 98 KHQAEVELCELADQVVAVGPKLTEAFACYLHSCGKGQDVINLTPGIFSEFANINQAAEERETFRVLVFGRGDseDFLVKGYDIASRAVAMLKD--E 191 ********************************999*************9999999999************9988**************99988..4 PP GT4-conflict 230 derveLvvrGapaeeaeelrerlaeiagepalevtvrpytkdraeleadlrraslvlmPSraEGFGLvglEAiaagvPvLvsseSGlaelLeekls 325 +++ +Lv +Gap+++ ++++er+ + p ++ vr+ k+r+el++++ +a+lv+mPSr+E FGL++lEA++agvPvLvs +SGl++ L++ l FUN_002408-T1 192 ERSFKLVFVGAPDGDEDKVKERFLKEGILP-SQLIVRS-AKERNELAKQFYEADLVMMPSRTEAFGLAALEALSAGVPVLVSGNSGLGKALKKVL- 284 5559****************9999865555.6788887.7899***************************************************6. PP GT4-conflict 326 eeeaerlvvpvtgddeedaeewaraieevlrdlea.aferaaelreeLaerltWaaaaasL 385 ++++ v ++++ ++wa+ai+++ ++ ++ + ++a lr+ ae ++W+ +++L FUN_002408-T1 285 ---IGSYFVVNSENP----KKWAKAIRTICSKEKElRLREAIFLRQSYAETYQWEGQCNTL 338 ...455666657777....8*********988766156789999****999****998876 PP >> Glycos_transf_1 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.2 0.1 1.4e-23 2.6e-20 27 161 .. 175 313 .. 148 319 .. 0.84 2 ? -3.2 0.0 4 7.3e+03 21 57 .. 1176 1212 .. 1174 1214 .. 0.83 Alignments for each domain: == domain 1 score: 73.2 bits; conditional E-value: 1.4e-23 Glycos_transf_1 27 eKgldlllkafaklkeklkpdlklviaG..dgeeekklkklaeklglednvkflgfvsdedlpellkiadvfvlpsrsEgfGivllEAmaaglp 118 +Kg+d + +a+a lk++ + +klv++G dg+e+k ++ ++ l ++++ +++++l + + ad++ +psr+E+fG+++lEA++ag+p FUN_002408-T1 175 VKGYDIASRAVAMLKDE-ERSFKLVFVGapDGDEDKVKERFLKEGILPSQLIVRSAKERNELAKQFYEADLVMMPSRTEAFGLAALEALSAGVP 267 6*************986.***********88888666666666666677777777777************************************ PP Glycos_transf_1 119 viasdvgglrevvkdge..tGllvkpnnaealaeaiekllede.el 161 v++s ++gl + +k+ + ++v ++n++++a+ai+ + ++e el FUN_002408-T1 268 VLVSGNSGLGKALKKVLigSYFVVNSENPKKWAKAIRTICSKEkEL 313 ***************994444666666*************998433 PP == domain 2 score: -3.2 bits; conditional E-value: 4 Glycos_transf_1 21 vgrlekeKgldlllkafaklkeklkpdlklviaGdge 57 +gr ++ ++ +++f++ + + +++l ++++G+++ FUN_002408-T1 1176 YGRTPLMQAMHHSVDLFSHSQFANQKKLLFILCGGEP 1212 6777888889999999999988899999999999655 PP >> Glyco_trans_1_4 Glycosyl transferases group 1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.6 0.0 3.1e-19 5.6e-16 4 139 .. 162 307 .. 159 309 .. 0.79 2 ? 0.5 0.0 0.52 9.5e+02 77 122 .. 750 796 .. 675 804 .. 0.56 3 ? 2.1 0.0 0.17 3.1e+02 14 123 .. 1017 1132 .. 1010 1144 .. 0.62 Alignments for each domain: == domain 1 score: 59.6 bits; conditional E-value: 3.1e-19 Glyco_trans_1_4 4 ilfvGrl.ae..nekgvdllleavplvrkkerdvrlvivG..dgpeeeeeleelak..gledr...veftGfvedlaellaaadvfvlPslseg 87 +l +Gr +e +kg d+ +av+ ++++er ++lv+vG dg +e++++e+ g+ ++ v+ ++++la+ + +ad++++Ps++e FUN_002408-T1 162 VLVFGRGdSEdfLVKGYDIASRAVAMLKDEERSFKLVFVGapDG--DEDKVKERFLkeGILPSqliVRSAKERNELAKQFYEADLVMMPSRTEA 253 66777775446667**************88338*******4444..44588885533766655433444444588******************* PP Glyco_trans_1_4 88 fglkllEAmaaglPvVatdvggipevvedgeng..llvppgdpealaeailrll 139 fgl++lEA++ag+Pv ++ +g+ ++++ g ++v++++p+++a+ai+++ FUN_002408-T1 254 FGLAALEALSAGVPVLVSGNSGLGKALKKVLIGsyFVVNSENPKKWAKAIRTIC 307 ******************99899998877755566999************9876 PP == domain 2 score: 0.5 bits; conditional E-value: 0.52 Glyco_trans_1_4 77 dvfvlPsl...segfglkllEAmaaglPvVatdvggipevvedgengll 122 +v++ P+ ++gfg +l + a+ l a++ ++e++e+g++ ll FUN_002408-T1 750 EVVLQPCKlsgKRGFGGMVLSYTAHDLVGWASES-SVREAIEKGKQ-LL 796 4566666666666999999999999998888888.77898888875.55 PP == domain 3 score: 2.1 bits; conditional E-value: 0.17 Glyco_trans_1_4 14 ekgvdllleavplvrkker.dvrlvivGdgp.eeeeeleelakgledrveftGfved......laellaaa.dvfvlPsl...segfglkll 93 +k + l++++ ++++ + +vr+ G+ + + l ++++ + ++ +++d l+ l +++ +v+v P ++gfg +l FUN_002408-T1 1017 RKQLTELIDEMMDILER-NgAVRFRSWGRMDvLLK-VLDKATA--AAMLYYLQRRPDfarrfvLECLPQDCrEVVVQPRKlsgKRGFGGMVL 1104 58899999999888878.55899999996653222.3332221..22244444443321122133333333256666766776679999999 PP Glyco_trans_1_4 94 EAmaaglPvVatdvggipevvedgengllv 123 + a+ l a++ ++e++e+g++ ll+ FUN_002408-T1 1105 SYTAHDLVGWASES-SVREAMEKGKQ-LLA 1132 99999999888888.77888888875.555 PP >> CCB2_CCB4 Cofactor assembly of complex C subunit B, CCB2/CCB4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.8 0.0 0.047 85 124 168 .. 546 590 .. 524 608 .. 0.78 2 ? 2.3 0.0 0.068 1.2e+02 123 165 .. 715 760 .. 695 777 .. 0.77 3 ? 4.9 0.0 0.011 20 123 184 .. 882 943 .. 862 950 .. 0.83 4 ? 2.9 0.0 0.044 80 124 165 .. 1051 1095 .. 1030 1111 .. 0.78 Alignments for each domain: == domain 1 score: 2.8 bits; conditional E-value: 0.047 CCB2_CCB4 124 ilervlkkqkevyLvdlklypgrvefdylpentqavlvqplgdeg 168 +l +++ yL + + r f+ lp++++ v++qp ++ g FUN_002408-T1 546 VLDKATAATMLYYLKRRLDFARRFVFECLPQECREVVIQPHNRLG 590 5555555555666666669999999***************87655 PP == domain 2 score: 2.3 bits; conditional E-value: 0.068 CCB2_CCB4 123 ailervlkkqkevyLvdlklypgrvefdylpentqavlvqpl...g 165 ++l +++ yL + + r + lp++++ v++qp g FUN_002408-T1 715 KVLDKATAAAMLYYLQRRPDFARRFVLECLPQDCREVVLQPCklsG 760 556666666677889999999999999**************95553 PP == domain 3 score: 4.9 bits; conditional E-value: 0.011 CCB2_CCB4 123 ailervlkkqkevyLvdlklypgrvefdylpentqavlvqplgdegvlilgsnaprsftkkD 184 ++l +++ yL + + r + lp+++ v+vqp + +g g a s+t +D FUN_002408-T1 882 KVLDKATAAAMLYYLQRRPDFARRFVLECLPQDCLEVVVQPCKLSGKRGFGRMAVISYTAQD 943 556666666677889999999999999***************88888888888889999888 PP == domain 4 score: 2.9 bits; conditional E-value: 0.044 CCB2_CCB4 124 ilervlkkqkevyLvdlklypgrvefdylpentqavlvqpl...g 165 +l +++ yL + + r + lp++++ v+vqp g FUN_002408-T1 1051 VLDKATAAAMLYYLQRRPDFARRFVLECLPQDCREVVVQPRklsG 1095 56666666677889999999999999**************84443 PP >> KPBB_C Phosphorylase b kinase C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.3 0.0 0.24 4.4e+02 176 188 .. 44 56 .. 38 61 .. 0.86 2 ? 3.4 0.0 0.027 50 148 181 .. 511 544 .. 504 586 .. 0.90 3 ? 2.9 0.0 0.04 73 146 182 .. 679 715 .. 668 739 .. 0.82 4 ? 2.3 0.0 0.06 1.1e+02 146 182 .. 846 882 .. 835 906 .. 0.82 5 ? 3.5 0.0 0.027 49 143 182 .. 1011 1050 .. 1001 1074 .. 0.83 Alignments for each domain: == domain 1 score: 0.3 bits; conditional E-value: 0.24 KPBB_C 176 vldvlighAvrla 188 +dv+igh +rl+ FUN_002408-T1 44 HMDVVIGHGIRLG 56 59*********97 PP == domain 2 score: 3.4 bits; conditional E-value: 0.027 KPBB_C 148 yrqltiEaLeaLaaiveknpdlqiedtlvldvli 181 r+ +E + +++ i+e+n ++i +dvl+ FUN_002408-T1 511 SRKQGTELIDEMMDILERNGAVRIRTWWEMDVLL 544 688889**************************97 PP == domain 3 score: 2.9 bits; conditional E-value: 0.04 KPBB_C 146 peyrqltiEaLeaLaaiveknpdlqiedtlvldvlig 182 + r+ +E + +++ i+e+n +++ +dvl+ FUN_002408-T1 679 LSSRKQLTELIDEMMDILERNGAVRVRSWGRVDVLLK 715 56788889*******************9999999874 PP == domain 4 score: 2.3 bits; conditional E-value: 0.06 KPBB_C 146 peyrqltiEaLeaLaaiveknpdlqiedtlvldvlig 182 + r+ +E + +++ i+e+n +++ +dvl+ FUN_002408-T1 846 LSSRKQLTELIDEMMYILERNGAIRVRSWGRVDVLLK 882 56788889*******************9999999874 PP == domain 5 score: 3.5 bits; conditional E-value: 0.027 KPBB_C 143 ieapeyrqltiEaLeaLaaiveknpdlqiedtlvldvlig 182 i+ + r+ +E + +++ i+e+n +++ +dvl+ FUN_002408-T1 1011 IKMLSSRKQLTELIDEMMDILERNGAVRFRSWGRMDVLLK 1050 66667889999********************999999974 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.9 0.0 0.062 1.1e+02 3 17 .. 431 448 .. 429 532 .. 0.61 2 ! 10.3 0.0 0.00062 1.1 43 107 .. 1143 1210 .. 1115 1211 .. 0.78 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.062 VWA_2 3 fvlDnSgSmrngdy...g 17 +++D+S Smrn+ + FUN_002408-T1 431 ILVDVSVSMRNSAGdrvN 448 89********99553341 PP == domain 2 score: 10.3 bits; conditional E-value: 0.00062 VWA_2 43 vtfsdnpevliplt..kdkakllealrrleat.gggtdlaaAlqlarkalkkrrrknakriivlitDg 107 v+ ++++ + ++ + dk+++ e l+++e++ g t l +A++ +++ + +++n+k+ ++++++g FUN_002408-T1 1143 VQSASDILHKSTGKkeLDKKRVDELLKAVEPYiYGRTPLMQAMHHSVDLFSHSQFANQKKLLFILCGG 1210 555555544444432458999*******************************************9998 PP >> DUF7185 Family of unknown function (DUF7185) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.12 2.2e+02 10 43 .. 613 646 .. 604 660 .. 0.86 2 ? 4.4 0.0 0.039 72 10 42 .. 780 812 .. 772 825 .. 0.87 3 ? 3.8 0.0 0.06 1.1e+02 10 43 .. 948 981 .. 934 994 .. 0.82 4 ? -0.8 0.0 1.7 3.1e+03 10 39 .. 1115 1144 .. 1107 1157 .. 0.82 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.12 DUF7185 10 kidreirtaiaeGaivsdevrliralievvavev 43 + ++ +r+ai +G+ e+r r i++v+v FUN_002408-T1 613 ASESSVREAIEKGKQLLTEIRSERPDIKMVPVSE 646 56899*************************9974 PP == domain 2 score: 4.4 bits; conditional E-value: 0.039 DUF7185 10 kidreirtaiaeGaivsdevrliralievvave 42 + ++ +r+ai +G+ +e+r r i++v+v FUN_002408-T1 780 ASESSVREAIEKGKQLLAEIRSERPNIKMVPVS 812 56899**************************98 PP == domain 3 score: 3.8 bits; conditional E-value: 0.06 DUF7185 10 kidreirtaiaeGaivsdevrliralievvavev 43 + ++ +r+ai G+ +e+r r i++v+v FUN_002408-T1 948 ASESSVREAIEMGKQLLAEIRSERPNIKMVPVSK 981 56899**************************984 PP == domain 4 score: -0.8 bits; conditional E-value: 1.7 DUF7185 10 kidreirtaiaeGaivsdevrliralievv 39 + ++ +r+a+ +G+ +e+r r++ v+ FUN_002408-T1 1115 ASESSVREAMEKGKQLLAEIRSERTIRSVQ 1144 567899**************9999876665 PP >> Pup Pup-like protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 0.99 1.8e+03 43 56 .. 517 530 .. 499 537 .. 0.79 2 ? 6.7 0.1 0.01 19 16 63 .. 665 707 .. 653 708 .. 0.78 3 ? 3.6 0.0 0.1 1.8e+02 16 62 .. 832 873 .. 820 875 .. 0.77 4 ? 3.8 0.2 0.087 1.6e+02 16 56 .. 1000 1035 .. 987 1042 .. 0.66 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 0.99 Pup 43 alLDeIDevLEeNa 56 +l+De+ ++LE N FUN_002408-T1 517 ELIDEMMDILERNG 530 68999999***996 PP == domain 2 score: 6.7 bits; conditional E-value: 0.01 Pup 16 eveettaeaeassevkerkeelsedvDalLDeIDevLEeNaeeFVrsf 63 e +e+++ea+ ++++ rk+ +l+De+ ++LE N Vrs+ FUN_002408-T1 665 ENDEEKVEARHIKDLSSRKQL-----TELIDEMMDILERNGAVRVRSW 707 667777888888888888776.....678888889*****99888875 PP == domain 3 score: 3.6 bits; conditional E-value: 0.1 Pup 16 eveettaeaeassevkerkeelsedvDalLDeIDevLEeNaeeFVrs 62 e +e+++ea+ ++++ rk+ +l+De+ +LE N Vrs FUN_002408-T1 832 ENDEEKVEARHIKDLSSRKQL-----TELIDEMMYILERNGAIRVRS 873 667777788777888877776.....679999999****99888887 PP == domain 4 score: 3.8 bits; conditional E-value: 0.087 Pup 16 eveettaeaeassevkerkeelsedvDalLDeIDevLEeNa 56 e +e+++ea+ + ++ rk+ +l+De+ ++LE N FUN_002408-T1 1000 EKDEEEVEASHIKMLSSRKQL-----TELIDEMMDILERNG 1035 556666666555555555544.....567777778999885 PP >> UTP20 U3 small nucleolar RNA-associated protein 20 domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.041 76 65 122 .. 742 799 .. 738 806 .. 0.76 2 ? -1.0 0.0 0.78 1.4e+03 63 112 .. 907 957 .. 905 971 .. 0.77 3 ? 7.8 0.0 0.0015 2.8 80 159 .. 1092 1171 .. 1074 1194 .. 0.84 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.041 UTP20 65 evLGpkyLpfilkelksaLtrGyqlhVlsytvhalLealepeleegdlDscledilei 122 e+L +++ +++l+ k +rG+ Vlsyt h l+ +++ +++ + ++ei FUN_002408-T1 742 ECLPQDCREVVLQPCKLSGKRGFGGMVLSYTAHDLVGWASESSVREAIEKGKQLLAEI 799 56666666777888888889***************98886666666777777666666 PP == domain 2 score: -1.0 bits; conditional E-value: 0.78 UTP20 63 ilevLGpkyLpfilkelksaLtrGy.qlhVlsytvhalLealepeleegdl 112 +le+L +++L+++++ k +rG+ ++ V syt + l+ +++ + FUN_002408-T1 907 VLECLPQDCLEVVVQPCKLSGKRGFgRMAVISYTAQDLMGWASESSVREAI 957 678999999***************95689******9999766555444445 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0015 UTP20 80 ksaLtrGyqlhVlsytvhalLealepeleegdlDscledileiiledifgevaeekeveeikkkvkEakssksydtlell 159 k +rG+ Vlsyt h l+ +++ +++ + ++ei +e +v + ++ + + kE+ +++ + l+ + FUN_002408-T1 1092 KLSGKRGFGGMVLSYTAHDLVGWASESSVREAMEKGKQLLAEIRSERTIRSVQSASDILHKSTGKKELDKKRVDELLKAV 1171 555589****************999888889**********************999999999999999999988877766 PP >> DUF6990 Family of unknown function (DUF6990) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.6 0.0 0.022 41 97 132 .. 602 637 .. 578 645 .. 0.85 2 ? 1.0 0.0 0.28 5e+02 102 132 .. 774 804 .. 768 811 .. 0.89 3 ? 0.5 0.0 0.41 7.4e+02 100 132 .. 940 972 .. 931 1019 .. 0.88 4 ? 2.6 0.0 0.09 1.6e+02 102 134 .. 1109 1141 .. 1102 1150 .. 0.89 Alignments for each domain: == domain 1 score: 4.6 bits; conditional E-value: 0.022 DUF6990 97 irqlseraiewaseqdiekalkkyrelptdakgarp 132 + +e ++ wase +++a++k ++l t+ ++ rp FUN_002408-T1 602 VSYTAEDLMGWASESSVREAIEKGKQLLTEIRSERP 637 66778999**********************999998 PP == domain 2 score: 1.0 bits; conditional E-value: 0.28 DUF6990 102 eraiewaseqdiekalkkyrelptdakgarp 132 + ++ wase +++a++k ++l ++ ++ rp FUN_002408-T1 774 HDLVGWASESSVREAIEKGKQLLAEIRSERP 804 56899*******************9999998 PP == domain 3 score: 0.5 bits; conditional E-value: 0.41 DUF6990 100 lseraiewaseqdiekalkkyrelptdakgarp 132 ++ ++ wase +++a++ ++l ++ ++ rp FUN_002408-T1 940 TAQDLMGWASESSVREAIEMGKQLLAEIRSERP 972 5678899***********999999999999887 PP == domain 4 score: 2.6 bits; conditional E-value: 0.09 DUF6990 102 eraiewaseqdiekalkkyrelptdakgarplr 134 + ++ wase +++a++k ++l ++ ++ r +r FUN_002408-T1 1109 HDLVGWASESSVREAMEKGKQLLAEIRSERTIR 1141 57899***********************99998 PP >> PanZ Acetyltransferase (GNAT) domain, PanZ # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 2.9 5.2e+03 49 71 .. 492 513 .. 491 555 .. 0.64 2 ? 3.0 0.0 0.05 92 75 108 .. 624 654 .. 598 662 .. 0.79 3 ? 2.6 0.0 0.067 1.2e+02 79 108 .. 792 821 .. 773 829 .. 0.86 4 ? 2.1 0.0 0.097 1.8e+02 78 104 .. 959 985 .. 935 998 .. 0.84 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 2.9 PanZ 49 LLgavkvelsdeeaeLsdLcvRe 71 LLg+v+v+ ++ ++ ++dL R+ FUN_002408-T1 492 LLGTVRVATEGAHG-IKDLSSRK 513 78888888887665.67776654 PP == domain 2 score: 3.0 bits; conditional E-value: 0.05 PanZ 75 rRGvGqyLleevkrqlPevkewklasedlkalee 108 + G++Ll e++ + P++k ++++++ +++ FUN_002408-T1 624 K---GKQLLTEIRSERPDIKMVPVSEAAIMSVQS 654 4...99***************9999999888775 PP == domain 3 score: 2.6 bits; conditional E-value: 0.067 PanZ 79 GqyLleevkrqlPevkewklasedlkalee 108 G++Ll e++ + P++k ++++++ +++ FUN_002408-T1 792 GKQLLAEIRSERPNIKMVPVSKAGIMSVQS 821 99****************999999988776 PP == domain 4 score: 2.1 bits; conditional E-value: 0.097 PanZ 78 vGqyLleevkrqlPevkewklasedlk 104 +G++Ll e++ + P++k ++++++ FUN_002408-T1 959 MGKQLLAEIRSERPNIKMVPVSKAGIM 985 69***************9999988876 PP >> VapC50_C VapC50 C-terminal domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.48 8.7e+02 34 48 .. 519 533 .. 510 534 .. 0.88 2 ? 0.8 0.0 0.32 5.9e+02 34 48 .. 689 703 .. 679 706 .. 0.84 3 ? 6.2 0.0 0.0067 12 13 49 .. 1003 1039 .. 1000 1041 .. 0.84 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.48 VapC50_C 34 veelLdrLerqGlpq 48 ++e d+Ler+G+++ FUN_002408-T1 519 IDEMMDILERNGAVR 533 6899********986 PP == domain 2 score: 0.8 bits; conditional E-value: 0.32 VapC50_C 34 veelLdrLerqGlpq 48 ++e d+Ler+G+++ FUN_002408-T1 689 IDEMMDILERNGAVR 703 7999********987 PP == domain 3 score: 6.2 bits; conditional E-value: 0.0067 VapC50_C 13 paavlaavrrqrarlknPPltveelLdrLerqGlpqf 49 +++v a+ ++ +++k ++e d+Ler+G+++f FUN_002408-T1 1003 EEEVEASHIKMLSSRKQLTELIDEMMDILERNGAVRF 1039 566666666899999999999**************99 PP >> FlgN FlgN protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.5 0.0 0.067 1.2e+02 91 139 .. 679 727 .. 619 730 .. 0.86 2 ? 1.9 0.0 0.21 3.8e+02 92 139 .. 847 894 .. 819 896 .. 0.88 3 ? 3.6 0.0 0.065 1.2e+02 81 139 .. 1006 1062 .. 982 1065 .. 0.83 Alignments for each domain: == domain 1 score: 3.5 bits; conditional E-value: 0.067 FlgN 91 kelwqelkelleelkelnelNgelieqslefvnrslnilqgaakasntY 139 +++l+el+ e ++ e+Ng++ +s +v+ +l++l +a +a ++Y FUN_002408-T1 679 LSSRKQLTELIDEMMDILERNGAVRVRSWGRVDVLLKVLDKATAAAMLY 727 56789**********************************9999998888 PP == domain 2 score: 1.9 bits; conditional E-value: 0.21 FlgN 92 elwqelkelleelkelnelNgelieqslefvnrslnilqgaakasntY 139 +++l+el+ e + e+Ng++ +s +v+ +l++l +a +a ++Y FUN_002408-T1 847 SSRKQLTELIDEMMYILERNGAIRVRSWGRVDVLLKVLDKATAAAMLY 894 57899*********************************9999998888 PP == domain 3 score: 3.6 bits; conditional E-value: 0.065 FlgN 81 llakeedeeLkelwqelkelleelkelnelNgelieqslefvnrslnilqgaakasntY 139 + a ++ + +++l+el+ e ++ e+Ng++ +s + + +l++l +a +a ++Y FUN_002408-T1 1006 VEA--SHIKMLSSRKQLTELIDEMMDILERNGAVRFRSWGRMDVLLKVLDKATAAAMLY 1062 444..6777788999********************************999999998888 PP >> UPF0367 UPF0367 protein family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.2 0.0096 17 29 65 .. 617 653 .. 613 657 .. 0.94 2 ? 5.5 0.2 0.014 26 29 65 .. 784 820 .. 780 824 .. 0.94 3 ? -0.5 0.1 1.1 2e+03 29 62 .. 952 985 .. 949 989 .. 0.86 4 ? -0.9 0.0 1.4 2.5e+03 29 48 .. 1119 1138 .. 1117 1141 .. 0.88 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0096 UPF0367 29 eileamrsgspelleLtCekqeeKkiavlsseisAVq 65 +++ea+++g++ l e+++e+ K + v i++Vq FUN_002408-T1 617 SVREAIEKGKQLLTEIRSERPDIKMVPVSEAAIMSVQ 653 799*********************************9 PP == domain 2 score: 5.5 bits; conditional E-value: 0.014 UPF0367 29 eileamrsgspelleLtCekqeeKkiavlsseisAVq 65 +++ea+++g++ l e+++e+ + K + v i++Vq FUN_002408-T1 784 SVREAIEKGKQLLAEIRSERPNIKMVPVSKAGIMSVQ 820 799*********************************9 PP == domain 3 score: -0.5 bits; conditional E-value: 1.1 UPF0367 29 eileamrsgspelleLtCekqeeKkiavlsseis 62 +++ea++ g++ l e+++e+ + K + v i+ FUN_002408-T1 952 SVREAIEMGKQLLAEIRSERPNIKMVPVSKAGIM 985 6999******999*******99999988776665 PP == domain 4 score: -0.9 bits; conditional E-value: 1.4 UPF0367 29 eileamrsgspelleLtCek 48 +++eam++g++ l e+++e+ FUN_002408-T1 1119 SVREAMEKGKQLLAEIRSER 1138 699******99999999987 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (1317 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 936 (0.0366412); expected 510.9 (0.02) Passed bias filter: 775 (0.0303386); expected 510.9 (0.02) Passed Vit filter: 66 (0.00258368); expected 25.5 (0.001) Passed Fwd filter: 16 (0.000626346); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 14 [number of targets reported over threshold] # CPU time: 0.49u 0.41s 00:00:00.89 Elapsed: 00:00:00.43 # Mc/sec: 12235.61 // Query: FUN_002409-T1 [L=737] Description: FUN_002409 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00018 22.3 0.0 0.0013 19.5 0.0 2.1 2 VWA von Willebrand factor type A domain 0.00028 21.5 0.0 0.00067 20.3 0.0 1.6 1 Peptidase_C1 Papain family cysteine protease 0.0014 19.7 0.3 4.1 8.5 0.0 2.8 3 VWA_2 von Willebrand factor type A domain ------ inclusion threshold ------ 0.098 11.9 0.1 0.16 11.2 0.1 1.3 1 Peptidase_C1_2 Peptidase C1-like family Domain annotation for each model (and alignments): >> VWA von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.0 0.22 1.4e+03 3 15 .. 6 18 .. 5 42 .. 0.83 2 ! 19.5 0.0 2e-07 0.0013 62 139 .. 296 366 .. 242 405 .. 0.79 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.22 VWA 3 vfllDgSgsigee 15 +l+D Sgs++++ FUN_002409-T1 6 GILVDVSGSMRNN 18 68********654 PP == domain 2 score: 19.5 bits; conditional E-value: 2e-07 VWA 62 eellsavkslkykgggttntgkalkyalenlfkssagaRegapkvvvlltdGksqdgdveeaarelksagvkvfavgv 139 ++ll+av+ y +g t + +a+++ ++ + s+ +++k++++l+dG+++d ++++++l + gv+v+ + + FUN_002409-T1 296 DDLLEAVEP--YIYGRTP-LMQAMRHSVDLFSLSEFA---NHKKLLFILSDGQPTD-GWDPPVQQLSDLGVTVVSCLI 366 344444444..6777777.9*********66666666...****************.999*************98766 PP >> Peptidase_C1 Papain family cysteine protease # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 1e-07 0.00067 127 205 .. 549 636 .. 526 644 .. 0.73 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1e-07 Peptidase_C1 127 lkkavakngPvsvaidasekdfqlYks.......Gvyket.......ecsk.telnhavllvGygtengkdyWivkNsWgtdwgekGYiriarg 205 ++a+ +++Pv v+++ + +++ ++++ G+++ + + + + hav+l y+ + + NsWg+dw ++G++r++++ FUN_002409-T1 549 AMEAISAKRPVVVTFHLTGAQWDQFEKfydenpgGILTRSyldskpiS--TsGAGGHAVVLTSYDAD----SLRLMNSWGDDWADQGFFRVQNS 636 678899999999999988775544432111233378887755444322..235789********998....56789**************9965 PP >> VWA_2 von Willebrand factor type A domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.00065 4.1 3 24 .. 7 28 .. 5 51 .. 0.79 2 ! 8.4 0.0 0.00069 4.4 58 108 .] 291 342 .. 240 342 .. 0.87 3 ? -3.9 0.0 4 2.6e+04 72 86 .. 477 491 .. 468 497 .. 0.71 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.00065 VWA_2 3 fvlDnSgSmrngdygptrleaa 24 +++D+SgSmrn+ ++ + e+a FUN_002409-T1 7 ILVDVSGSMRNNAGSEVNEERA 28 89*********97655554444 PP == domain 2 score: 8.4 bits; conditional E-value: 0.00069 VWA_2 58 dkakllealrrleat.gggtdlaaAlqlarkalkkrrrknakriivlitDge 108 d + + + l+++e++ g t l +A++ +++ +++n+k+ +++++Dg+ FUN_002409-T1 291 DEKWVDDLLEAVEPYiYGRTPLMQAMRHSVDLFSLSEFANHKKLLFILSDGQ 342 5677888999999999**********************************96 PP == domain 3 score: -3.9 bits; conditional E-value: 4 VWA_2 72 tgggtdlaaAlqlar 86 ++ggt++a+A + FUN_002409-T1 477 QHGGTCYANASAAVM 491 379999999966554 PP >> Peptidase_C1_2 Peptidase C1-like family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 2.5e-05 0.16 359 427 .. 601 664 .. 592 670 .. 0.78 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 2.5e-05 Peptidase_C1_2 359 ltHamvltgvdvdddgkvtkwkvEnsWGedsGekGyfvmsde.wfdeyvyevvvdkkylpeellealeee 427 Ha+vlt+ d +++ nsWG+d ++G+f + ++ + ++v + l+e++++a+e++ FUN_002409-T1 601 GGHAVVLTSYDA------DSLRLMNSWGDDWADQGFFRVQNSnVLGLEFFDVFWTLDDLSEKEKKAYEHH 664 569999999998......568999*************776650555556888888899999998888875 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (737 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 843 (0.0330006); expected 510.9 (0.02) Passed bias filter: 806 (0.0315522); expected 510.9 (0.02) Passed Vit filter: 63 (0.00246624); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.39u 0.42s 00:00:00.81 Elapsed: 00:00:00.43 # Mc/sec: 6902.92 // Query: FUN_002410-T1 [L=292] Description: FUN_002410 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-28 100.6 0.0 7.8e-24 85.0 0.1 2.2 2 Pkinase Protein kinase domain 1e-20 74.7 0.0 1.9e-20 73.8 0.0 1.5 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.0033 17.1 0.0 0.0068 16.1 0.0 1.4 1 ABC1 ABC1 atypical kinase-like domain ------ inclusion threshold ------ 0.043 13.0 0.2 0.38 9.9 0.1 2.0 2 Pkinase_fungal Fungal protein kinase Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.0 0.1 1.2e-27 7.8e-24 1 152 [. 55 209 .. 55 212 .. 0.90 2 ! 14.3 0.0 4.4e-06 0.028 176 259 .. 210 286 .. 206 288 .. 0.80 Alignments for each domain: == domain 1 score: 85.0 bits; conditional E-value: 1.2e-27 Pkinase 1 yevleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdlls...... 90 y++++++G+Gsfg+ yka++ + ++++K+ +++ +++ ++ + ++iv+++++ e ++ ++++Ey+egg+++d+++ FUN_002410-T1 55 YRIEKTVGRGSFGVTYKATNIGGSFTFCLKMCGYVEEEILA-------LDLARNDNVKEIVKYYGAKLEGRKAFICMEYMEGGTVKDHIEqqrevl 143 7889****************************998766544.......78999999**********************************877777 PP Pkinase 91 ...rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLid.ekgelKitDFGlakelesss 152 + ++ ee++ ++++ il+gl++l s+g+vH D+K +N+L+ + ++K++DFGl++++e++ FUN_002410-T1 144 pvdAWPIIAEEKCFDLVSDILKGLAFLNSKGLVHGDIKGDNVLLVeSCTHVKLADFGLSRKIEEHV 209 76444458888*********************************956677***********99875 PP == domain 2 score: 14.3 bits; conditional E-value: 4.4e-06 Pkinase 176 kkvDvWslGvilyelltgkppfsaekekekvekeldqlekilkielkeklpepssiseeakdllkkllkkdpkkRltaeellqh 259 + DvW G++ +e+l+g+ ++ v +q + + ++ps+ s++ k++lk +++++ k+ ++a e+l++ FUN_002410-T1 210 DNRDVWKTGCLHIEMLNGERSSL---HDGFVFGGGQQ----GQRSVIPGKHFPSQASKKTKEFLKLIFCVNRKHLPSAAEMLHD 286 567****************9998...44444444444....233455678999**************************99985 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 73.8 0.0 2.9e-24 1.9e-20 3 156 .. 57 209 .. 55 239 .. 0.86 Alignments for each domain: == domain 1 score: 73.8 bits; conditional E-value: 2.9e-24 PK_Tyr_Ser-Thr 3 lkeklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk.. 95 +++++G+G+fG yk+t + + ++K++ ++ ee + ++l ++ + ++ivk++g+ +e+++ +i +ey+egG++k++++++ FUN_002410-T1 57 IEKTVGRGSFGVTYKATNI----GGSFTFCLKMC--GYVEE----EILALDLARNDNVKEIVKYYGAKLEGRKAFICMEYMEGGTVKDHIEQQre 141 7899************999....89999*****9..44444....2456788888899***********************************89 PP PK_Tyr_Ser-Thr 96 ......keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvse.kkvvkisDfGLardvekdd 156 + ++ ++l+ +i kG+++L+sk lvH d+ NvL+ e ++vk++DfGL+r++e++ FUN_002410-T1 142 vlpvdaWPIIAEEKCFDLVSDILKGLAFLNSKGLVHGDIKGDNVLLVEsCTHVKLADFGLSRKIEEHV 209 999887777888999*****************************97762569************4433 PP >> ABC1 ABC1 atypical kinase-like domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 1.1e-06 0.0068 143 222 .. 119 209 .. 115 217 .. 0.80 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 1.1e-06 ABC1 143 ervLtmeyvdGikiddleale...........eagidrkeiaeklvelfleqifedgffhaDphpGNllvr.kdgelvllDfGlmgeldekf 222 + ++ mey++G ++d+ + + a+ + ++++++++ ++ + +g++h D N+l+ + +++ l DfGl+++++e+ FUN_002410-T1 119 KAFICMEYMEGGTVKDHIEQQrevlpvdawpiIAEEKCFDLVSDILKGLA-FLNSKGLVHGDIKGDNVLLVeSCTHVKLADFGLSRKIEEHV 209 56789*********999888878888888777667777777777777544.47789***********87651566999**********9875 PP >> Pkinase_fungal Fungal protein kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.03 1.9e+02 184 207 .. 90 113 .. 52 141 .. 0.85 2 ? 9.9 0.1 6e-05 0.38 292 366 .. 160 226 .. 152 235 .. 0.77 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.03 Pkinase_fungal 184 keEaelLkeaeergvegvarlvah 207 +eE L +a++ +v++++++++ FUN_002410-T1 90 EEEILALDLARNDNVKEIVKYYGA 113 47888999************9975 PP == domain 2 score: 9.9 bits; conditional E-value: 6e-05 Pkinase_fungal 292 lrdaikahrsLyekagiLHrDISinNimiteeekegdrkglLIDLDlaielsessasgarertGTleFmaiellk 366 d +k++ L +g++H+DI N++++e+ + L D+ l+ +++e+ ++ + +tG l ie+l+ FUN_002410-T1 160 VSDILKGLAFLN-SKGLVHGDIKGDNVLLVES----CTHVKLADFGLSRKIEEHVDNRDVWKTGCL---HIEMLN 226 568889998888.9****************65....566889999999999987777777788765...366666 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (292 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 460 (0.0180074); expected 510.9 (0.02) Passed bias filter: 424 (0.0165982); expected 510.9 (0.02) Passed Vit filter: 44 (0.00172245); expected 25.5 (0.001) Passed Fwd filter: 4 (0.000156586); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.41 # Mc/sec: 2891.11 // Query: FUN_002411-T1 [L=89] Description: FUN_002411 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (89 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 400 (0.0156586); expected 510.9 (0.02) Passed bias filter: 317 (0.0124095); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.24u 0.40s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 903.64 // Query: FUN_002413-T1 [L=109] Description: FUN_002413 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (109 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 659 (0.0257976); expected 510.9 (0.02) Passed bias filter: 411 (0.0160893); expected 510.9 (0.02) Passed Vit filter: 16 (0.000626346); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.36s 00:00:00.63 Elapsed: 00:00:00.39 # Mc/sec: 1115.73 // Query: FUN_002414-T1 [L=64] Description: FUN_002414 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (64 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 317 (0.0124095); expected 510.9 (0.02) Passed bias filter: 313 (0.0122529); expected 510.9 (0.02) Passed Vit filter: 21 (0.000822079); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.22u 0.39s 00:00:00.61 Elapsed: 00:00:00.38 # Mc/sec: 676.20 // Query: FUN_002415-T1 [L=100] Description: FUN_002415 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.6e-05 24.9 0.0 1.8e-05 24.8 0.0 1.1 1 Pkinase Protein kinase domain 0.0056 16.5 0.0 0.0063 16.3 0.0 1.1 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 1.4e-09 1.8e-05 91 150 .. 32 92 .. 11 98 .. 0.81 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 1.4e-09 Pkinase 91 rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLidekge.lKitDFGlakeles 150 + +a+ +e++ ++ ++++l+ +Hs+ +H D+K eNi + g K +D G a ++ FUN_002415-T1 32 DGTAIAQETCLAFVGDLFTALDSMHSKARIHGDIKAENIVLVGCGSrQKPADSGAAGDIQG 92 456689999999****************************995555589999888887765 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.3 0.0 5e-07 0.0063 95 153 .. 26 91 .. 10 100 .] 0.78 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 5e-07 PK_Tyr_Ser-Thr 95 k......keklslkellklalqiAkGmeyLeskklvHrdlaarNv.LvsekkvvkisDfGLardve 153 + +++ +++ l ++ ++ +++ ++sk +H d+ a N+ Lv + k +D G a d++ FUN_002415-T1 26 QennpsdGTAIAQETCLAFVGDLFTALDSMHSKARIHGDIKAENIvLVGCGSRQKPADSGAAGDIQ 91 45555556788899999***************************7377788999999999888884 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (100 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 476 (0.0186338); expected 510.9 (0.02) Passed bias filter: 413 (0.0161675); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.35s 00:00:00.65 Elapsed: 00:00:00.40 # Mc/sec: 1000.18 // Query: FUN_002416-T1 [L=289] Description: FUN_002416 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (289 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 823 (0.0322177); expected 510.9 (0.02) Passed bias filter: 489 (0.0191427); expected 510.9 (0.02) Passed Vit filter: 27 (0.00105696); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.32u 0.39s 00:00:00.71 Elapsed: 00:00:00.42 # Mc/sec: 2805.05 // Query: FUN_002417-T1 [L=128] Description: FUN_002417 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-06 26.8 0.2 5.9e-06 26.4 0.2 1.1 1 Pkinase Protein kinase domain ------ inclusion threshold ------ 0.03 14.1 0.1 0.042 13.6 0.1 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.4 0.2 4.6e-10 5.9e-06 3 89 .. 44 123 .. 42 127 .. 0.89 Alignments for each domain: == domain 1 score: 26.4 bits; conditional E-value: 4.6e-10 Pkinase 3 vleklGeGsfgkVykaveketgkivAiKkikkekakkkkekkvlrEikilkklkhpnivrlidvfeekdelylvlEyveggelfdll 89 vlek+G+G+fg++yka+ +++ ++++Kk k + ++ +++ k+ k + iv ++++ + + +++Ey++g++ ++++ FUN_002417-T1 44 VLEKIGSGAFGECYKAYTSNDPSFFCVKKTKYKVNELLA-------LHLAKEGKVDTIVDYYGAKVQGGNANIFIEYLTGKKKTKVV 123 789**************************9998776544.......789999999***********************999876665 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 3.3e-06 0.042 4 85 .. 45 116 .. 43 124 .. 0.84 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 3.3e-06 PK_Tyr_Ser-Thr 4 keklGeGafGeVykgtlkeekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyveg 85 ek+G+GafGe yk++ + ++ +vK+ k + +e ++l k+ + + iv ++g+ +++++ i +ey++g FUN_002417-T1 45 LEKIGSGAFGECYKAYTS----NDPSFFCVKKTKYKVNEL------LALHLAKEGKVDTIVDYYGAKVQGGNANIFIEYLTG 116 589*************99....888889999997766665......4566677778899*********99999999999865 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (128 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 749 (0.0293208); expected 510.9 (0.02) Passed bias filter: 576 (0.0225484); expected 510.9 (0.02) Passed Vit filter: 32 (0.00125269); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.28u 0.36s 00:00:00.64 Elapsed: 00:00:00.40 # Mc/sec: 1297.68 // Query: FUN_002418-T1 [L=283] Description: FUN_002418 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-20 73.7 0.1 2e-19 70.5 0.0 2.0 2 Pkinase Protein kinase domain 6.4e-12 45.8 0.0 9.4e-12 45.3 0.0 1.2 1 PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase Domain annotation for each model (and alignments): >> Pkinase Protein kinase domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.5 0.0 1.5e-23 2e-19 3 152 .. 44 203 .. 42 208 .. 0.81 2 ? 1.6 0.0 0.017 2.1e+02 176 196 .. 205 225 .. 200 256 .. 0.91 Alignments for each domain: == domain 1 score: 70.5 bits; conditional E-value: 1.5e-23 Pkinase 3 vleklGeGsfgkVykaveketgkivAiKkikkekakkkke.kkvlrEikilkklk...hpnivrlidvfeekdelylvlEyveggelfdlls.... 90 v++++G+Gs+g+Vyka++k++ ++ + ++ k+ k +l+E+ l+ k + iv + ++ e+ + ++++E+++gg+l+d++ FUN_002418-T1 44 VVKEIGSGSSGVVYKAYQKRSTRHT----RNDSSFFCIKKtKYILDELLALSLAKkesIETIVDFRGAKVENGNAIIFMELMKGGTLTDHVLrqke 135 789**************87776654....333333333333668889877766664458999************************9998876676 PP Pkinase 91 .....rkgalseeeakkilkqilegleylHsegvvHrDlKpeNiLidekge.lKitDFGlakelesss 152 + ++ ee+++ +++ i+++l++lH++g+++ +K eNiL+ e+g +K++D G a +++ FUN_002418-T1 136 nlpagTWPIIAEETCSVYIRDIFTALDFLHRNGLFYGGIKGENILVYEDGShIKLADCGSAGDIQEPG 203 6765444458888**********************************88877*********9998765 PP == domain 2 score: 1.6 bits; conditional E-value: 0.017 Pkinase 176 kkvDvWslGvilyelltgkpp 196 ++ DvW ++++ +l+g++p FUN_002418-T1 205 ASKDVWESSCVFLGMLNGEMP 225 567***************998 PP >> PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.3 0.0 7.4e-16 9.4e-12 4 154 .. 45 201 .. 43 215 .. 0.80 Alignments for each domain: == domain 1 score: 45.3 bits; conditional E-value: 7.4e-16 PK_Tyr_Ser-Thr 4 keklGeGafGeVykgtlke...ekekkkikVavKtlkeeaseeekeefleeaklmkklshpnivkllgvcteeepllivteyvegGsLkefLrkk 95 +++G+G+ G Vyk++ k+ ++++++ ++K+ k +e l ++l kk s + iv + g+ +e+++ +i +e+++gG+L +++ ++ FUN_002418-T1 45 VKEIGSGSSGVVYKAYQKRstrHTRNDSSFFCIKKTKYILDE------LLALSLAKKESIETIVDFRGAKVENGNAIIFMELMKGGTLTDHVLRQ 133 589**************9955445555555667766444333......4578889999******************************9876666 PP PK_Tyr_Ser-Thr 96 ........keklslkellklalqiAkGmeyLeskklvHrdlaarNvLvsekk.vvkisDfGLardvek 154 + ++ ++++i ++++L+++ l + N+Lv e+ ++k++D G a d+++ FUN_002418-T1 134 kenlpagtWPIIAEETCSVYIRDIFTALDFLHRNGLFYGGIKGENILVYEDGsHIKLADCGSAGDIQE 201 4777777444455566667899**************************986559*******9998855 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (283 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 412 (0.0161284); expected 510.9 (0.02) Passed bias filter: 404 (0.0158152); expected 510.9 (0.02) Passed Vit filter: 26 (0.00101781); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.37s 00:00:00.68 Elapsed: 00:00:00.40 # Mc/sec: 2834.66 // Query: FUN_002419-T1 [L=93] Description: FUN_002419 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.18 12.1 1.5 0.98 9.7 0.2 2.0 2 Neuropeptide_S Neuropeptide S precursor protein 0.19 11.8 0.0 0.28 11.4 0.0 1.2 1 Choline_kin_N Choline kinase N terminus Domain annotation for each model (and alignments): >> Neuropeptide_S Neuropeptide S precursor protein # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.7 0.2 7.7e-05 0.98 5 39 .. 13 48 .. 10 54 .. 0.75 2 ? 2.9 0.1 0.01 1.3e+02 11 32 .. 50 73 .. 44 83 .. 0.70 Alignments for each domain: == domain 1 score: 9.7 bits; conditional E-value: 7.7e-05 Neuropeptide_S 5 ssklsgksDyf.LiLLssClarvgrseeLallKPll 39 +++++ s ++++ssC+a +++ L l+K l FUN_002419-T1 13 TCEVTSSSSCHiILVMSSCKAWLDPRSPLFLKKQLF 48 56666555544055589************9999775 PP == domain 2 score: 2.9 bits; conditional E-value: 0.01 Neuropeptide_S 11 ksDyfLiL..LssClarvgrseeL 32 k D +++L L sCl+++ L FUN_002419-T1 50 KDDRTVVLatLMSCLSAISHPMSL 73 666666654599***999776555 PP >> Choline_kin_N Choline kinase N terminus # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 2.2e-05 0.28 12 37 .. 30 60 .. 20 67 .. 0.92 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 2.2e-05 Choline_kin_N 12 svkaplDislPsdy.....FKqdilrllhtL 37 s+ka lD + P+++ FK+d +l+tL FUN_002419-T1 30 SCKAWLDPRSPLFLkkqlfFKDDRTVVLATL 60 8***************************999 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (93 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 510 (0.0199648); expected 510.9 (0.02) Passed bias filter: 392 (0.0153455); expected 510.9 (0.02) Passed Vit filter: 31 (0.00121354); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.25u 0.34s 00:00:00.59 Elapsed: 00:00:00.39 # Mc/sec: 972.60 // Query: FUN_002420-T1 [L=174] Description: FUN_002420 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.12 12.5 0.4 0.24 11.5 0.4 1.6 1 SAP SAP domain 0.21 12.2 0.0 0.44 11.1 0.0 1.5 1 Rsbr_N Rsbr N terminal Domain annotation for each model (and alignments): >> SAP SAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.4 1.9e-05 0.24 3 37 .] 30 66 .. 28 66 .. 0.92 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 1.9e-05 SAP 3 skltvseLKeeLkkrGLptsGk..KaeLieRLkeyle 37 s+l+ eL+ L+ r + +G Ka L++R++ey++ FUN_002420-T1 30 SSLKNEELRFWLRCREDSLKGLktKALLVKRVEEYVK 66 899999****************9***********975 PP >> Rsbr_N Rsbr N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 3.5e-05 0.44 4 49 .. 53 98 .. 51 106 .. 0.90 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 3.5e-05 Rsbr_N 4 nkdelvkewlkelkelrkeeylqkisdelyeetskefvdlilssvk 49 k+ lvk+ ++ +k+ r++++++ +de+y++ k v++++ss FUN_002420-T1 53 TKALLVKRVEEYVKSGRDQMVIDPDPDEIYTKRKKRIVNIMMSSTP 98 67889*************************************9976 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (174 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 478 (0.0187121); expected 510.9 (0.02) Passed bias filter: 393 (0.0153846); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.36s 00:00:00.62 Elapsed: 00:00:00.39 # Mc/sec: 1812.54 // Query: FUN_002421-T1 [L=167] Description: FUN_002421 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.11 13.2 0.0 0.18 12.4 0.0 1.3 1 Rsbr_N Rsbr N terminal 0.11 12.7 0.4 0.23 11.6 0.4 1.6 1 SAP SAP domain Domain annotation for each model (and alignments): >> Rsbr_N Rsbr N terminal # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 1.4e-05 0.18 4 51 .. 53 100 .. 51 106 .. 0.90 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 1.4e-05 Rsbr_N 4 nkdelvkewlkelkelrkeeylqkisdelyeetskefvdlilssvken 51 k+ lvk+ ++ +k+ r++++++ +de+y++ k v++++ss +++ FUN_002421-T1 53 TKALLVKRVEEYVKSGRDQMVIDPDPDEIYTKRKKRIVNVMMSSTTSS 100 67889**************************************98854 PP >> SAP SAP domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.4 1.8e-05 0.23 3 37 .] 30 66 .. 28 66 .. 0.92 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 1.8e-05 SAP 3 skltvseLKeeLkkrGLptsGk..KaeLieRLkeyle 37 s+l+ eL+ L+ r + +G Ka L++R++ey++ FUN_002421-T1 30 SSLKNEELRFWLRCREDSLKGLktKALLVKRVEEYVK 66 899999****************9***********975 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (167 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 776 (0.0303778); expected 510.9 (0.02) Passed bias filter: 614 (0.024036); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.26u 0.43s 00:00:00.69 Elapsed: 00:00:00.41 # Mc/sec: 1653.07 // Query: FUN_002422-T1 [L=88] Description: FUN_002422 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.17 11.9 0.1 0.2 11.7 0.1 1.1 1 UNC119_bdg UNC119-binding protein C5orf30 homologue Domain annotation for each model (and alignments): >> UNC119_bdg UNC119-binding protein C5orf30 homologue # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.1 7.7e-06 0.2 97 138 .. 23 66 .. 7 76 .. 0.68 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 7.7e-06 UNC119_bdg 97 hrssriykaksryy.qpydipavnGrrrrrmpssg.dkclksla 138 +++ r yk s + + ++Grr+ rmp s+ d ks++ FUN_002422-T1 23 AKAQRAYKIESFTCeKHFTDEDIDGRRKMRMPPSSlDMNRKSVP 66 567777777765541445666789*******8666155556655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (88 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 559 (0.021883); expected 510.9 (0.02) Passed bias filter: 449 (0.0175768); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 1 (3.91466e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.27u 0.34s 00:00:00.61 Elapsed: 00:00:00.39 # Mc/sec: 916.03 // Query: FUN_002424-T1 [L=399] Description: FUN_002424 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.073 14.1 0.8 0.073 14.1 0.8 4.4 6 CPG4 Chondroitin proteoglycan 4 0.11 12.9 0.1 0.21 11.9 0.1 1.5 1 DUF4218 Domain of unknown function (DUF4218) Domain annotation for each model (and alignments): >> CPG4 Chondroitin proteoglycan 4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.1 0.45 5.8e+03 72 89 .. 19 36 .. 15 41 .. 0.79 2 ? -2.0 1.5 0.6 7.6e+03 39 46 .. 61 70 .. 21 100 .. 0.56 3 ? 14.1 0.8 5.8e-06 0.073 2 59 .. 113 172 .. 112 185 .. 0.84 4 ? -0.8 0.1 0.26 3.3e+03 63 93 .. 201 230 .. 196 231 .. 0.80 5 ? -1.6 0.3 0.45 5.7e+03 13 23 .. 220 230 .. 209 265 .. 0.47 6 ? 4.2 2.3 0.0068 87 24 47 .. 317 347 .. 291 369 .. 0.61 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 0.45 CPG4 72 eqikClqeaaedvqkeCe 89 ++ +C q+a+e++ k C FUN_002424-T1 19 ANSSCSQRAFEIAGKSCV 36 667899999999999995 PP == domain 2 score: -2.0 bits; conditional E-value: 0.6 CPG4 39 eCvek..kkC 46 Cv++ +kC FUN_002424-T1 61 PCVRSivEKC 70 3444333444 PP == domain 3 score: 14.1 bits; conditional E-value: 5.8e-06 CPG4 2 ClrkClkplakllasleaaknvverlkkvCekleeaseCvek..kkCddktlfealtsaf 59 C +k l+ +k+ +s++++ v+ +C+k+++a eC+ + ++C+++ +ea + f FUN_002424-T1 113 CPEKVLQRTRKCAHSFHKEFREVKGSPSLCSKFTKARECIVRalQRCEKSPTVEATLKMF 172 9999999999**9999999999*****************988799**8877666555544 PP == domain 4 score: -0.8 bits; conditional E-value: 0.26 CPG4 63 CidkeekleeqikClqeaaedvqkeCeekCa 93 C ++e +++ + +C+ + + +q++ +++C FUN_002424-T1 201 CTEREYSFK-TRRCILSFVRALQSQPKKHCR 230 777777775.568999999999999999995 PP == domain 5 score: -1.6 bits; conditional E-value: 0.45 CPG4 13 llasleaaknv 23 +l+s +++ FUN_002424-T1 220 ALQSQPKKHCR 230 44333333332 PP == domain 6 score: 4.2 bits; conditional E-value: 0.0068 CPG4 24 verlkkvCekleeaseCvek...kkC....d 47 ++ k +C+k++ea++C ++ C + FUN_002424-T1 317 NKSDKSLCRKYAEAKRCTKNatlSLCkvtrE 347 3556789**********98742334554443 PP >> DUF4218 Domain of unknown function (DUF4218) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.1 1.7e-05 0.21 44 108 .. 270 336 .. 262 340 .. 0.82 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 1.7e-05 DUF4218 44 LateaklaGPvhyrnmypverkllrl.ksyvrnkarpeGciaeaylaeea.ltfcsryleeietkfn 108 ++e k++ +h++ yp + k + k+yv+ k e + +e+yl++++ ++c +y e + +n FUN_002424-T1 270 ASDEQKFCDGIHFQLSYPRNLKQNDCeKNYVEVKQACESSYVETYLKNKSdKSLCRKYAEAKRCTKN 336 56788999999*******98777766489*******************9935789999987665554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (399 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 1150 (0.0450186); expected 510.9 (0.02) Passed bias filter: 594 (0.0232531); expected 510.9 (0.02) Passed Vit filter: 38 (0.00148757); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.31u 0.36s 00:00:00.67 Elapsed: 00:00:00.39 # Mc/sec: 4074.94 // Query: FUN_002425-T1 [L=433] Description: FUN_002425 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- ------ inclusion threshold ------ 0.17 12.2 0.7 0.69 10.2 0.2 2.0 2 YkuI_C EAL-domain associated signalling protein domain Domain annotation for each model (and alignments): >> YkuI_C EAL-domain associated signalling protein domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.2 2.7e-05 0.69 25 90 .. 49 114 .. 31 137 .. 0.80 2 ? -0.3 0.0 0.046 1.2e+03 82 104 .. 221 245 .. 202 286 .. 0.78 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 2.7e-05 YkuI_C 25 klealyelaeklkqrlkellkklkkaedydelllalakeldevafrvyicdedGiqqssnvek.kdg 90 k + ++ l+e+l+ ++++++k k+ +d +l + ++++ + ++ + y+c+ dG+ s +k +d FUN_002425-T1 49 KHDCQLFLSERLTPCVHNIVEKCKNVADKANLEIMMSRAHNITSQKSYLCE-DGMLNSFKNFKsRDC 114 67788899******************************************6.677666655663554 PP == domain 2 score: -0.3 bits; conditional E-value: 0.046 YkuI_C 82 ssnvekkdgewklqkeyl..aknws 104 +n kk+ +w ++++y+ +kn + FUN_002425-T1 221 LQNQPKKHCRWAFMNKYYfcTKNIA 245 5788899999**9999983346655 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (433 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 911 (0.0356626); expected 510.9 (0.02) Passed bias filter: 485 (0.0189861); expected 510.9 (0.02) Passed Vit filter: 35 (0.00137013); expected 25.5 (0.001) Passed Fwd filter: 3 (0.00011744); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.35u 0.38s 00:00:00.73 Elapsed: 00:00:00.42 # Mc/sec: 4147.74 // Query: FUN_002426-T1 [L=226] Description: FUN_002426 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.00051 20.3 0.2 0.00051 20.3 0.2 2.0 2 PAN_1 PAN domain 0.0087 16.6 6.2 0.16 12.5 0.0 2.8 3 PAN_4 PAN domain Domain annotation for each model (and alignments): >> PAN_1 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.5 1.3 0.54 6.9e+03 30 38 .. 86 95 .. 72 99 .. 0.70 2 ! 20.3 0.2 4e-08 0.00051 11 57 .. 147 198 .. 127 213 .. 0.86 Alignments for each domain: == domain 1 score: -2.5 bits; conditional E-value: 0.54 PAN_1 30 rCaeekr.Cr 38 +C++ k+ Cr FUN_002426-T1 86 ACTNPKEcCR 95 5666666555 PP == domain 2 score: 20.3 bits; conditional E-value: 4e-08 PAN_1 11 legedkktvtvssaeeCaqrCaeekrCrsftYnek.....skkCllksessg 57 +g+ ++++++ s+++C C+ e+rC f+ ++ +k C+l +e ++ FUN_002426-T1 147 SDGHVIVQHKAFSLTHCSDFCLREPRCGGFNLETVshpkgKKLCELLDEVGN 198 455888888888**********************************999876 PP >> PAN_4 PAN domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 3.9 3.2 0.0064 81 30 48 .. 76 94 .. 72 95 .. 0.87 2 ? -1.6 0.0 0.33 4.3e+03 42 51 .] 122 131 .. 113 131 .. 0.75 3 ! 12.5 0.0 1.2e-05 0.16 15 50 .. 157 192 .. 147 193 .. 0.82 Alignments for each domain: == domain 1 score: 3.9 bits; conditional E-value: 0.0064 PAN_4 30 rCnawvfvkpglkgsearC 48 Cn++++++ ++++++ +C FUN_002426-T1 76 HCNGYSYQNLACTNPKECC 94 6********9999999988 PP == domain 2 score: -1.6 bits; conditional E-value: 0.33 PAN_4 42 kgsearCwLK 51 + +++C LK FUN_002426-T1 122 REIDRVCSLK 131 677899***9 PP == domain 3 score: 12.5 bits; conditional E-value: 1.2e-05 PAN_4 15 vdspeaCcaaCdedprCnawvfvkpglkgsearCwL 50 + s +C + C ++prC ++ + + + ++ C L FUN_002426-T1 157 AFSLTHCSDFCLREPRCGGFNLETVSHPKGKKLCEL 192 558899**************9999888888888876 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (226 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 502 (0.0196516); expected 510.9 (0.02) Passed bias filter: 358 (0.0140145); expected 510.9 (0.02) Passed Vit filter: 22 (0.000861225); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.23u 0.43s 00:00:00.66 Elapsed: 00:00:00.39 # Mc/sec: 2328.17 // Query: FUN_002427-T1 [L=220] Description: FUN_002427 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 0.0083 16.4 0.1 6.3 7.2 0.1 2.7 2 LEAP-2 Liver-expressed antimicrobial peptide 2 precursor ( ------ inclusion threshold ------ 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 DUF6810 Family of unknown function (DUF6810) Domain annotation for each model (and alignments): >> LEAP-2 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.0 0.0 0.0011 15 35 66 .. 78 111 .. 66 120 .. 0.70 2 ! 7.2 0.1 0.0005 6.3 32 66 .. 140 184 .. 130 194 .. 0.69 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0011 LEAP-2 35 lrrmt.PfwrgvslrPi.Gascrddsecitrlcr 66 ++ +t + ++s+rPi a+ +ds+ it c+ FUN_002427-T1 78 TKELTgTLPYALSMRPIlIAASSEDSQDITSACQ 111 444441345699****844667889999**9996 PP == domain 2 score: 7.2 bits; conditional E-value: 0.0005 LEAP-2 32 krrlrrmtPfwrgvslrPi..........Gascrddsecitrlcr 66 + r+r ++Pfw +v l + Ga se trlcr FUN_002427-T1 140 HDRRREISPFWLAVLLEDVqvevvgytgeGANITLSSEEDTRLCR 184 4588899******99876533333444445666666777777777 PP >> DUF6810 Family of unknown function (DUF6810) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 1.9e-05 0.24 44 88 .. 31 75 .. 6 87 .. 0.86 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 1.9e-05 DUF6810 44 iRfypshqeAvelGtalaeevsGedailsketstwkeGvkdrrea 88 i+ p++q+A++ Gt ee G +a + + + Gv++ + FUN_002427-T1 31 IKKRPNKQSAIKDGTGSKEEDRGREAVMREFVREYGKGVRQENVR 75 6666899********************************987554 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (220 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 585 (0.0229008); expected 510.9 (0.02) Passed bias filter: 443 (0.0173419); expected 510.9 (0.02) Passed Vit filter: 29 (0.00113525); expected 25.5 (0.001) Passed Fwd filter: 2 (7.82932e-05); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.37s 00:00:00.67 Elapsed: 00:00:00.40 # Mc/sec: 2200.58 // Query: FUN_002428-T1 [L=101] Description: FUN_002428 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (101 residues searched) Target model(s): 25545 (4079224 nodes) Passed MSV filter: 660 (0.0258368); expected 510.9 (0.02) Passed bias filter: 583 (0.0228225); expected 510.9 (0.02) Passed Vit filter: 37 (0.00144842); expected 25.5 (0.001) Passed Fwd filter: 0 (0); expected 0.3 (1e-05) Initial search space (Z): 25545 [actual number of targets] Domain search space (domZ): 0 [number of targets reported over threshold] # CPU time: 0.27u 0.37s 00:00:00.64 Elapsed: 00:00:00.39 # Mc/sec: 1039.62 //